PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
571,864 sequences; 207,016,062 total letters
Results from round 1
Query= sp|P29597|TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2
OS=Homo sapiens OX=9606 GN=TYK2 PE=1 SV=3
Length=1187
Score E
Sequences producing significant alignments: (Bits) Value
sp|P29597|TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 OS... 2455 0.0
sp|Q9R117|TYK2_MOUSE Non-receptor tyrosine-protein kinase TYK2 OS... 1919 0.0
sp|P23458|JAK1_HUMAN Tyrosine-protein kinase JAK1 OS=Homo sapiens... 1014 0.0
sp|P52332|JAK1_MOUSE Tyrosine-protein kinase JAK1 OS=Mus musculus... 1013 0.0
sp|O12990|JAK1_DANRE Tyrosine-protein kinase JAK1 OS=Danio rerio ... 990 0.0
sp|Q09178|JAK1_CYPCA Tyrosine-protein kinase JAK1 OS=Cyprinus car... 920 0.0
sp|Q75R65|JAK2_CHICK Tyrosine-protein kinase JAK2 OS=Gallus gallu... 781 0.0
sp|Q62689|JAK2_RAT Tyrosine-protein kinase JAK2 OS=Rattus norvegi... 765 0.0
sp|Q62120|JAK2_MOUSE Tyrosine-protein kinase JAK2 OS=Mus musculus... 764 0.0
sp|Q5RB23|JAK2_PONAB Tyrosine-protein kinase JAK2 OS=Pongo abelii... 759 0.0
sp|O60674|JAK2_HUMAN Tyrosine-protein kinase JAK2 OS=Homo sapiens... 759 0.0
sp|O19064|JAK2_PIG Tyrosine-protein kinase JAK2 OS=Sus scrofa OX=... 759 0.0
sp|P52333|JAK3_HUMAN Tyrosine-protein kinase JAK3 OS=Homo sapiens... 684 0.0
sp|Q62137|JAK3_MOUSE Tyrosine-protein kinase JAK3 OS=Mus musculus... 671 0.0
sp|Q63272|JAK3_RAT Tyrosine-protein kinase JAK3 OS=Rattus norvegi... 660 0.0
sp|O54967|ACK1_MOUSE Activated CDC42 kinase 1 OS=Mus musculus OX=... 182 3e-45
sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens OX=... 181 5e-45
sp|Q17R13|ACK1_BOVIN Activated CDC42 kinase 1 OS=Bos taurus OX=99... 179 2e-44
sp|Q5U2X5|ACK1_RAT Activated CDC42 kinase 1 OS=Rattus norvegicus ... 179 2e-44
sp|P24786|NTRK3_PIG NT-3 growth factor receptor OS=Sus scrofa OX=... 177 2e-44
sp|Q91044|NTRK3_CHICK NT-3 growth factor receptor OS=Gallus gallu... 177 4e-44
sp|Q5IS37|NTRK3_PANTR NT-3 growth factor receptor OS=Pan troglody... 174 2e-43
sp|Q5IFJ9|NTRK3_MACFA NT-3 growth factor receptor OS=Macaca fasci... 174 3e-43
sp|Q6VNS1|NTRK3_MOUSE NT-3 growth factor receptor OS=Mus musculus... 174 3e-43
sp|Q3UFB7|NTRK1_MOUSE High affinity nerve growth factor receptor ... 173 5e-43
sp|Q5IS82|NTRK3_SAIBB NT-3 growth factor receptor OS=Saimiri boli... 172 1e-42
sp|P35739|NTRK1_RAT High affinity nerve growth factor receptor OS... 171 2e-42
sp|Q63604|NTRK2_RAT BDNF/NT-3 growth factors receptor OS=Rattus n... 171 2e-42
sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens O... 164 9e-42
sp|Q16620|NTRK2_HUMAN BDNF/NT-3 growth factors receptor OS=Homo s... 169 9e-42
sp|F1N9Y5|KSYK_CHICK Tyrosine-protein kinase SYK OS=Gallus gallus... 166 9e-42
sp|P15209|NTRK2_MOUSE BDNF/NT-3 growth factors receptor OS=Mus mu... 169 9e-42
sp|P25911|LYN_MOUSE Tyrosine-protein kinase Lyn OS=Mus musculus O... 164 1e-41
sp|P53356|HTK16_HYDVU Tyrosine-protein kinase HTK16 OS=Hydra vulg... 168 1e-41
sp|Q91987|NTRK2_CHICK BDNF/NT-3 growth factors receptor OS=Gallus... 168 2e-41
sp|Q07014|LYN_RAT Tyrosine-protein kinase Lyn OS=Rattus norvegicu... 163 3e-41
sp|Q95KR7|LCK_SAISC Proto-oncogene tyrosine-protein kinase LCK OS... 163 3e-41
sp|P42679|MATK_HUMAN Megakaryocyte-associated tyrosine-protein ki... 163 3e-41
sp|Q61527|ERBB4_MOUSE Receptor tyrosine-protein kinase erbB-4 OS=... 169 3e-41
sp|Q5PXS1|LCK_AOTNA Tyrosine-protein kinase Lck OS=Aotus nancymaa... 162 4e-41
sp|Q14289|FAK2_HUMAN Protein-tyrosine kinase 2-beta OS=Homo sapie... 168 4e-41
sp|P41241|CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus musculus O... 161 5e-41
sp|P32577|CSK_RAT Tyrosine-protein kinase CSK OS=Rattus norvegicu... 161 5e-41
sp|P04629|NTRK1_HUMAN High affinity nerve growth factor receptor ... 167 5e-41
sp|P41242|MATK_MOUSE Megakaryocyte-associated tyrosine-protein ki... 162 6e-41
sp|Q16288|NTRK3_HUMAN NT-3 growth factor receptor OS=Homo sapiens... 166 7e-41
sp|P41240|CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo sapiens O... 160 7e-41
sp|P70600|FAK2_RAT Protein-tyrosine kinase 2-beta OS=Rattus norve... 167 8e-41
sp|Q0VBZ0|CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos taurus OX=... 160 1e-40
sp|Q15303|ERBB4_HUMAN Receptor tyrosine-protein kinase erbB-4 OS=... 167 1e-40
sp|P06240|LCK_MOUSE Proto-oncogene tyrosine-protein kinase LCK OS... 160 2e-40
sp|P42689|SRK3_SPOLA Tyrosine-protein kinase SRK3 (Fragment) OS=S... 156 2e-40
sp|P11273|ERBB_AVIEU Tyrosine-protein kinase transforming protein... 161 2e-40
sp|P41243|MATK_RAT Megakaryocyte-associated tyrosine-protein kina... 160 2e-40
sp|Q9QVP9|FAK2_MOUSE Protein-tyrosine kinase 2-beta OS=Mus muscul... 166 2e-40
sp|P42683|LCK_CHICK Proto-oncogene tyrosine-protein kinase LCK OS... 160 2e-40
sp|Q62956|ERBB4_RAT Receptor tyrosine-protein kinase erbB-4 OS=Ra... 166 2e-40
sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens OX=9... 166 3e-40
sp|P41239|CSK_CHICK Tyrosine-protein kinase CSK OS=Gallus gallus ... 158 4e-40
sp|Q01621|LCK_RAT Proto-oncogene tyrosine-protein kinase LCK OS=R... 159 4e-40
sp|P34152|FAK1_MOUSE Focal adhesion kinase 1 OS=Mus musculus OX=1... 165 5e-40
sp|P06239|LCK_HUMAN Tyrosine-protein kinase Lck OS=Homo sapiens O... 159 5e-40
sp|O35346|FAK1_RAT Focal adhesion kinase 1 OS=Rattus norvegicus O... 165 6e-40
sp|P42685|FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo sapiens O... 159 7e-40
sp|Q922K9|FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus musculus O... 159 7e-40
sp|P42690|SRK4_SPOLA Tyrosine-protein kinase isoform SRK4 OS=Spon... 159 7e-40
sp|P08631|HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo sapiens O... 159 1e-39
sp|Q24592|JAK_DROME Tyrosine-protein kinase hopscotch OS=Drosophi... 164 1e-39
sp|Q03142|FGFR4_MOUSE Fibroblast growth factor receptor 4 OS=Mus ... 162 1e-39
sp|P22455|FGFR4_HUMAN Fibroblast growth factor receptor 4 OS=Homo... 162 1e-39
sp|Q07407|FGFR1_DROME Fibroblast growth factor receptor homolog 1... 161 1e-39
sp|Q62662|FRK_RAT Tyrosine-protein kinase FRK OS=Rattus norvegicu... 157 2e-39
sp|Q24145|SHARK_DROME Tyrosine-protein kinase Shark OS=Drosophila... 162 2e-39
sp|Q498D6|FGFR4_RAT Fibroblast growth factor receptor 4 OS=Rattus... 161 3e-39
sp|P00522|ABL_DROME Tyrosine-protein kinase Abl OS=Drosophila mel... 163 3e-39
sp|Q91287|FGFR3_PLEWA Fibroblast growth factor receptor 3 OS=Pleu... 161 3e-39
sp|Q04589|FGFR1_RAT Fibroblast growth factor receptor 1 OS=Rattus... 161 4e-39
sp|P48025|KSYK_MOUSE Tyrosine-protein kinase SYK OS=Mus musculus ... 159 4e-39
sp|P21804|FGFR1_CHICK Fibroblast growth factor receptor 1 OS=Gall... 160 5e-39
sp|P43405|KSYK_HUMAN Tyrosine-protein kinase SYK OS=Homo sapiens ... 158 5e-39
sp|P00534|ERBB_ALV Tyrosine-protein kinase transforming protein e... 158 6e-39
sp|Q95YD4|KIN32_CAEEL Inactive tyrosine-protein kinase kin-32 OS=... 160 6e-39
sp|P00535|ERBB_AVIER Tyrosine-protein kinase transforming protein... 158 6e-39
sp|P50545|HCK_RAT Tyrosine-protein kinase HCK OS=Rattus norvegicu... 156 7e-39
sp|P08103|HCK_MOUSE Tyrosine-protein kinase HCK OS=Mus musculus O... 156 8e-39
sp|P11362|FGFR1_HUMAN Fibroblast growth factor receptor 1 OS=Homo... 160 9e-39
sp|P22182|FGFR1_XENLA Fibroblast growth factor receptor 1 OS=Xeno... 160 9e-39
sp|Q91009|NTRK1_CHICK High affinity nerve growth factor receptor ... 159 9e-39
sp|Q00944|FAK1_CHICK Focal adhesion kinase 1 OS=Gallus gallus OX=... 160 1e-38
sp|P16092|FGFR1_MOUSE Fibroblast growth factor receptor 1 OS=Mus ... 159 1e-38
sp|Q90Z00|FGR1A_DANRE Fibroblast growth factor receptor 1-A OS=Da... 159 1e-38
sp|Q95M30|HCK_MACFA Tyrosine-protein kinase HCK OS=Macaca fascicu... 154 2e-38
sp|P18460|FGFR3_CHICK Fibroblast growth factor receptor 3 OS=Gall... 158 2e-38
sp|Q91738|FAK1_XENLA Focal adhesion kinase 1 OS=Xenopus laevis OX... 159 2e-38
sp|P42688|SRK2_SPOLA Tyrosine-protein kinase SRK2 (Fragment) OS=S... 150 2e-38
sp|Q09147|FGFR2_DROME Fibroblast growth factor receptor homolog 2... 159 3e-38
sp|O42127|FGFR3_XENLA Fibroblast growth factor receptor 3 OS=Xeno... 158 3e-38
sp|P13388|XMRK_XIPMA Melanoma receptor tyrosine-protein kinase OS... 159 3e-38
sp|P22607|FGFR3_HUMAN Fibroblast growth factor receptor 3 OS=Homo... 158 3e-38
sp|P18461|FGFR2_CHICK Fibroblast growth factor receptor 2 OS=Gall... 158 4e-38
sp|Q9V9J3|SRC42_DROME Tyrosine-protein kinase Src42A OS=Drosophil... 154 4e-38
sp|Q90413|FGFR4_DANRE Fibroblast growth factor receptor 4 OS=Dani... 158 4e-38
sp|Q91147|FGFR2_NOTVI Fibroblast growth factor receptor 2 OS=Noto... 157 4e-38
sp|P43403|ZAP70_HUMAN Tyrosine-protein kinase ZAP-70 OS=Homo sapi... 155 4e-38
sp|Q91286|FGFR2_PLEWA Fibroblast growth factor receptor 2 OS=Pleu... 157 5e-38
sp|P21802|FGFR2_HUMAN Fibroblast growth factor receptor 2 OS=Homo... 157 5e-38
sp|P07949|RET_HUMAN Proto-oncogene tyrosine-protein kinase recept... 158 6e-38
sp|P21803|FGFR2_MOUSE Fibroblast growth factor receptor 2 OS=Mus ... 157 6e-38
sp|Q00655|KSYK_PIG Tyrosine-protein kinase SYK OS=Sus scrofa OX=9... 155 7e-38
sp|Q03351|NTRK3_RAT NT-3 growth factor receptor OS=Rattus norvegi... 157 7e-38
sp|Q91288|FGFR4_PLEWA Fibroblast growth factor receptor 4 OS=Pleu... 157 8e-38
sp|Q5RB22|ERBB3_PONAB Receptor tyrosine-protein kinase erbB-3 OS=... 158 8e-38
sp|Q61851|FGFR3_MOUSE Fibroblast growth factor receptor 3 OS=Mus ... 157 8e-38
sp|Q91285|FGFR1_PLEWA Fibroblast growth factor receptor 1 OS=Pleu... 156 1e-37
sp|Q62799|ERBB3_RAT Receptor tyrosine-protein kinase erbB-3 OS=Ra... 157 1e-37
sp|Q24488|ROR1_DROME Tyrosine-protein kinase transmembrane recept... 155 1e-37
sp|Q64725|KSYK_RAT Tyrosine-protein kinase SYK OS=Rattus norvegic... 154 1e-37
sp|Q03364|FGFR2_XENLA Fibroblast growth factor receptor 2 OS=Xeno... 156 1e-37
sp|P21860|ERBB3_HUMAN Receptor tyrosine-protein kinase erbB-3 OS=... 157 2e-37
sp|Q61526|ERBB3_MOUSE Receptor tyrosine-protein kinase erbB-3 OS=... 157 2e-37
sp|P55245|EGFR_MACMU Epidermal growth factor receptor OS=Macaca m... 157 2e-37
sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sap... 157 2e-37
sp|Q8JG38|FGFR2_DANRE Fibroblast growth factor receptor 2 OS=Dani... 155 2e-37
sp|Q01279|EGFR_MOUSE Epidermal growth factor receptor OS=Mus musc... 156 3e-37
sp|Q9I8X3|FGFR3_DANRE Fibroblast growth factor receptor 3 OS=Dani... 155 3e-37
sp|P43404|ZAP70_MOUSE Tyrosine-protein kinase ZAP-70 OS=Mus muscu... 152 4e-37
sp|G5EBZ8|ARK1_CAEEL Ack-related non-receptor tyrosine kinase OS=... 155 7e-37
sp|Q86PM4|FGFR_HYDVU Fibroblast growth factor receptor OS=Hydra v... 154 8e-37
sp|P42686|SRK1_SPOLA Tyrosine-protein kinase isoform SRK1 OS=Spon... 149 9e-37
sp|P0CY46|EGFR_APIME Epidermal growth factor receptor OS=Apis mel... 155 1e-36
sp|P17713|STK_HYDVU Tyrosine-protein kinase STK OS=Hydra vulgaris... 149 1e-36
sp|Q9H3Y6|SRMS_HUMAN Tyrosine-protein kinase Srms OS=Homo sapiens... 148 2e-36
sp|Q91743|FGFR4_XENLA Fibroblast growth factor receptor 4 OS=Xeno... 152 3e-36
sp|Q62371|DDR2_MOUSE Discoidin domain-containing receptor 2 OS=Mu... 152 3e-36
sp|Q62190|RON_MOUSE Macrophage-stimulating protein receptor OS=Mu... 153 4e-36
sp|Q62270|SRMS_MOUSE Tyrosine-protein kinase Srms OS=Mus musculus... 147 6e-36
sp|Q03145|EPHA2_MOUSE Ephrin type-A receptor 2 OS=Mus musculus OX... 151 7e-36
sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens OX... 151 8e-36
sp|P35546|RET_MOUSE Proto-oncogene tyrosine-protein kinase recept... 151 9e-36
sp|G3V9H8|RET_RAT Proto-oncogene tyrosine-protein kinase receptor... 151 9e-36
sp|P13406|FYN_XENLA Tyrosine-protein kinase Fyn OS=Xenopus laevis... 147 1e-35
sp|P00527|YES_AVISY Tyrosine-protein kinase transforming protein ... 146 1e-35
sp|P10447|ABL_FSVHY Tyrosine-protein kinase transforming protein ... 144 2e-35
sp|Q1KL86|EPHA2_MACFA Ephrin type-A receptor 2 OS=Macaca fascicul... 150 2e-35
sp|Q09YN5|MET_RABIT Hepatocyte growth factor receptor OS=Oryctola... 150 2e-35
sp|O02466|ILPR_BRALA Insulin-like peptide receptor OS=Branchiosto... 150 2e-35
sp|P16056|MET_MOUSE Hepatocyte growth factor receptor OS=Mus musc... 150 2e-35
sp|P27446|FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiphophorus he... 146 2e-35
sp|Q9VZI2|ACK_DROME Activated Cdc42 kinase Ack OS=Drosophila mela... 150 2e-35
sp|P09324|YES_CHICK Tyrosine-protein kinase Yes OS=Gallus gallus ... 146 2e-35
sp|P29321|EPHA8_RAT Ephrin type-A receptor 8 (Fragment) OS=Rattus... 142 2e-35
sp|P04412|EGFR_DROME Epidermal growth factor receptor OS=Drosophi... 150 3e-35
sp|P00521|ABL_MLVAB Tyrosine-protein kinase transforming protein ... 148 3e-35
sp|P10936|YES_XENLA Tyrosine-protein kinase Yes OS=Xenopus laevis... 145 4e-35
sp|Q90330|FGFR4_COTCO Fibroblast growth factor receptor 4 OS=Cotu... 147 4e-35
sp|Q2QLH6|MET_OTOGA Hepatocyte growth factor receptor OS=Otolemur... 150 4e-35
sp|A1A5H8|YES_DANRE Tyrosine-protein kinase yes OS=Danio rerio OX... 145 6e-35
sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens... 149 6e-35
sp|Q04912|RON_HUMAN Macrophage-stimulating protein receptor OS=Ho... 149 6e-35
sp|G5ECJ6|CSK1_CAEEL Tyrosine-protein kinase csk-1 OS=Caenorhabdi... 144 7e-35
sp|Q60553|ERBB2_MESAU Receptor tyrosine-protein kinase erbB-2 OS=... 149 7e-35
sp|Q2QLF1|MET_PANTR Hepatocyte growth factor receptor OS=Pan trog... 149 8e-35
sp|Q2IBD8|MET_PONAB Hepatocyte growth factor receptor OS=Pongo ab... 149 8e-35
sp|Q2IBF2|MET_GORGO Hepatocyte growth factor receptor OS=Gorilla ... 149 8e-35
sp|Q2IBA6|MET_CHLAE Hepatocyte growth factor receptor OS=Chloroce... 149 8e-35
sp|Q07DY1|MET_NOMLE Hepatocyte growth factor receptor OS=Nomascus... 149 8e-35
sp|P39688|FYN_MOUSE Tyrosine-protein kinase Fyn OS=Mus musculus O... 144 8e-35
sp|Q2QLC0|MET_PLEMO Hepatocyte growth factor receptor OS=Plecturo... 149 8e-35
sp|P08581|MET_HUMAN Hepatocyte growth factor receptor OS=Homo sap... 149 8e-35
sp|Q2QL89|MET_MICMU Hepatocyte growth factor receptor OS=Microceb... 149 8e-35
sp|Q2IBG7|MET_EULMM Hepatocyte growth factor receptor OS=Eulemur ... 149 8e-35
sp|A0M8R7|MET_PAPAN Hepatocyte growth factor receptor OS=Papio an... 148 8e-35
sp|Q2QLG5|MET_CALJA Hepatocyte growth factor receptor OS=Callithr... 148 9e-35
sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo sapiens O... 144 9e-35
sp|Q07DV8|MET_AOTNA Hepatocyte growth factor receptor OS=Aotus na... 148 9e-35
sp|Q09YH7|MET_SAIBB Hepatocyte growth factor receptor OS=Saimiri ... 148 1e-34
sp|Q07DZ1|MET_COLGU Hepatocyte growth factor receptor OS=Colobus ... 148 1e-34
sp|A1Y2K1|FYN_PIG Tyrosine-protein kinase Fyn OS=Sus scrofa OX=98... 144 1e-34
sp|P00520|ABL1_MOUSE Tyrosine-protein kinase ABL1 OS=Mus musculus... 148 1e-34
sp|Q09YL1|MET_ATEGE Hepatocyte growth factor receptor OS=Ateles g... 148 1e-34
sp|Q62844|FYN_RAT Tyrosine-protein kinase Fyn OS=Rattus norvegicu... 144 1e-34
sp|A0JNB0|FYN_BOVIN Tyrosine-protein kinase Fyn OS=Bos taurus OX=... 144 1e-34
sp|Q16832|DDR2_HUMAN Discoidin domain-containing receptor 2 OS=Ho... 147 1e-34
sp|P31693|SRC_RSVPA Tyrosine-protein kinase transforming protein ... 143 1e-34
sp|O18735|ERBB2_CANLF Receptor tyrosine-protein kinase erbB-2 OS=... 147 2e-34
sp|P29318|EPHA3_CHICK Ephrin type-A receptor 3 OS=Gallus gallus O... 147 2e-34
sp|Q1JPZ3|SRC_DANRE Proto-oncogene tyrosine-protein kinase Src OS... 143 2e-34
sp|Q26614|FGFR_STRPU Fibroblast growth factor receptor OS=Strongy... 147 2e-34
sp|P51813|BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX OS=Ho... 145 2e-34
sp|Q05688|IGF1R_BOVIN Insulin-like growth factor 1 receptor (Frag... 144 2e-34
sp|P06494|ERBB2_RAT Receptor tyrosine-protein kinase erbB-2 OS=Ra... 147 2e-34
sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src OS... 143 2e-34
sp|O13148|EPA4A_DANRE Ephrin type-A receptor 4a (Fragment) OS=Dan... 137 2e-34
sp|Q25410|MIPR_LYMST Putative molluscan insulin-related peptide(s... 147 2e-34
sp|P03949|ABL1_CAEEL Tyrosine-protein kinase abl-1 OS=Caenorhabdi... 147 2e-34
sp|Q09YK0|MET_MUNMU Hepatocyte growth factor receptor OS=Muntiacu... 147 2e-34
sp|Q6EWH2|FYNA_DANRE Tyrosine-protein kinase fyna OS=Danio rerio ... 143 2e-34
sp|Q2IBC0|MET_RHIFE Hepatocyte growth factor receptor OS=Rhinolop... 147 3e-34
sp|P04626|ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 OS=... 147 3e-34
sp|P51451|BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo sapiens O... 142 3e-34
sp|A1X150|MET_ECHTE Hepatocyte growth factor receptor OS=Echinops... 147 3e-34
sp|Q769I5|MET_BOVIN Hepatocyte growth factor receptor OS=Bos taur... 147 3e-34
sp|F1RDG9|FYNB_DANRE Tyrosine-protein kinase fynb OS=Danio rerio ... 142 3e-34
sp|P70424|ERBB2_MOUSE Receptor tyrosine-protein kinase erbB-2 OS=... 146 3e-34
sp|P63185|SRC_RSVSE Tyrosine-protein kinase transforming protein ... 142 3e-34
sp|P29320|EPHA3_HUMAN Ephrin type-A receptor 3 OS=Homo sapiens OX... 146 3e-34
sp|P00524|SRC_RSVSA Tyrosine-protein kinase transforming protein ... 142 4e-34
sp|Q09YI9|MET_SHEEP Hepatocyte growth factor receptor OS=Ovis ari... 146 4e-34
sp|Q00PJ8|MET_ATEAB Hepatocyte growth factor receptor OS=Atelerix... 146 4e-34
sp|Q8AXY6|MUSK_CHICK Muscle, skeletal receptor tyrosine protein k... 145 4e-34
sp|O08680|EPHA3_RAT Ephrin type-A receptor 3 OS=Rattus norvegicus... 145 5e-34
sp|Q2QLE0|MET_PIG Hepatocyte growth factor receptor OS=Sus scrofa... 146 5e-34
sp|Q9WUD9|SRC_RAT Proto-oncogene tyrosine-protein kinase Src OS=R... 142 5e-34
sp|P05480|SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src OS... 142 5e-34
sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens... 145 5e-34
sp|P54756|EPHA5_HUMAN Ephrin type-A receptor 5 OS=Homo sapiens OX... 145 6e-34
sp|P54755|EPHA5_CHICK Ephrin type-A receptor 5 OS=Gallus gallus O... 145 6e-34
sp|P42682|TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus musculus O... 141 6e-34
sp|P14084|SRC_AVISS Tyrosine-protein kinase transforming protein ... 142 6e-34
sp|P00526|SRC_RSVP Tyrosine-protein kinase transforming protein S... 141 7e-34
sp|P27447|YES_XIPHE Tyrosine-protein kinase Yes OS=Xiphophorus he... 141 7e-34
sp|P00525|SRC_AVISR Tyrosine-protein kinase transforming protein ... 141 7e-34
sp|Q8MY85|FGFR2_DUGJA Fibroblast growth factor receptor 2 OS=Duge... 144 7e-34
sp|P13115|SRC1_XENLA Tyrosine-protein kinase Src-1 OS=Xenopus lae... 141 7e-34
sp|Q2QLA9|MET_HORSE Hepatocyte growth factor receptor OS=Equus ca... 145 8e-34
sp|Q07E24|MET_MUSPF Hepatocyte growth factor receptor OS=Mustela ... 145 8e-34
sp|Q8MY86|FGFR1_DUGJA Fibroblast growth factor receptor 1 OS=Duge... 144 8e-34
sp|P29319|EPHA3_MOUSE Ephrin type-A receptor 3 OS=Mus musculus OX... 145 8e-34
sp|P00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src OS... 141 8e-34
sp|Q9YI66|TYRO3_DANRE Tyrosine-protein kinase receptor TYRO3 OS=D... 144 8e-34
sp|Q108U6|MET_LOXAF Hepatocyte growth factor receptor OS=Loxodont... 145 9e-34
sp|Q04736|YES_MOUSE Tyrosine-protein kinase Yes OS=Mus musculus O... 141 9e-34
sp|Q75ZY9|MET_CANLF Hepatocyte growth factor receptor OS=Canis lu... 145 1e-33
sp|Q07E01|MET_ORNAN Hepatocyte growth factor receptor OS=Ornithor... 145 1e-33
sp|P14085|SRC_AVIST Tyrosine-protein kinase transforming protein ... 141 1e-33
sp|P15054|SRC_AVIS2 Tyrosine-protein kinase transforming protein ... 142 1e-33
sp|Q4JIM5|ABL2_MOUSE Tyrosine-protein kinase ABL2 OS=Mus musculus... 145 1e-33
sp|Q02977|YRK_CHICK Proto-oncogene tyrosine-protein kinase Yrk OS... 141 1e-33
sp|P97523|MET_RAT Hepatocyte growth factor receptor OS=Rattus nor... 145 1e-33
sp|P07947|YES_HUMAN Tyrosine-protein kinase Yes OS=Homo sapiens O... 141 1e-33
sp|Q28923|YES_CANLF Tyrosine-protein kinase Yes OS=Canis lupus fa... 140 1e-33
sp|P13116|SRC2_XENLA Tyrosine-protein kinase Src-2 OS=Xenopus lae... 140 1e-33
sp|P54757|EPHA5_RAT Ephrin type-A receptor 5 OS=Rattus norvegicus... 144 1e-33
sp|P23049|SEA_AVIET Tyrosine-protein kinase transforming protein ... 137 2e-33
sp|Q60629|EPHA5_MOUSE Ephrin type-A receptor 5 OS=Mus musculus OX... 143 2e-33
sp|O13146|EPHA3_DANRE Ephrin type-A receptor 3 OS=Danio rerio OX=... 144 2e-33
sp|Q7YR43|DDR1_PANTR Epithelial discoidin domain-containing recep... 143 2e-33
sp|Q08345|DDR1_HUMAN Epithelial discoidin domain-containing recep... 143 2e-33
sp|P06213|INSR_HUMAN Insulin receptor OS=Homo sapiens OX=9606 GN=... 144 2e-33
sp|Q93105|INSR_AEDAE Insulin-like receptor OS=Aedes aegypti OX=71... 144 2e-33
sp|Q9I7F7|ACKL_DROME Activated Cdc42 kinase-like OS=Drosophila me... 144 2e-33
sp|P97504|BMX_MOUSE Cytoplasmic tyrosine-protein kinase BMX OS=Mu... 141 2e-33
sp|Q07E48|MET_DASNO Hepatocyte growth factor receptor OS=Dasypus ... 144 2e-33
sp|P33497|RYK_AVIR3 Tyrosine-protein kinase transforming protein ... 138 2e-33
sp|Q02858|TIE2_MOUSE Angiopoietin-1 receptor OS=Mus musculus OX=1... 143 2e-33
sp|P16277|BLK_MOUSE Tyrosine-protein kinase Blk OS=Mus musculus O... 139 2e-33
sp|Q06807|TIE2_BOVIN Angiopoietin-1 receptor OS=Bos taurus OX=991... 143 3e-33
sp|Q06806|TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mu... 143 3e-33
sp|P21709|EPHA1_HUMAN Ephrin type-A receptor 1 OS=Homo sapiens OX... 143 3e-33
sp|Q02763|TIE2_HUMAN Angiopoietin-1 receptor OS=Homo sapiens OX=9... 143 3e-33
sp|Q10656|EGL15_CAEEL Myoblast growth factor receptor egl-15 OS=C... 143 3e-33
sp|O76997|TRK1_LYMST Putative neurotrophin receptor LTRK 1 OS=Lym... 142 3e-33
sp|Q9PVZ4|INSR_XENLA Insulin receptor OS=Xenopus laevis OX=8355 G... 143 4e-33
sp|O15146|MUSK_HUMAN Muscle, skeletal receptor tyrosine-protein k... 142 4e-33
sp|Q07E37|MET_NEONE Hepatocyte growth factor receptor OS=Neofelis... 143 4e-33
sp|A0M8S8|MET_FELCA Hepatocyte growth factor receptor OS=Felis ca... 143 4e-33
sp|O45539|SRC2_CAEEL Tyrosine protein-kinase src-2 OS=Caenorhabdi... 138 5e-33
sp|Q95ZV7|DDRB_CAEEL Discoidin domain-containing receptor tyrosin... 141 5e-33
sp|Q4H3K6|FGFR_CIOIN Fibroblast growth factor receptor OS=Ciona i... 140 7e-33
sp|F1LM93|YES_RAT Tyrosine-protein kinase Yes OS=Rattus norvegicu... 138 8e-33
sp|Q95YM9|FGFR_HALRO Fibroblast growth factor receptor OS=Halocyn... 140 9e-33
sp|Q12866|MERTK_HUMAN Tyrosine-protein kinase Mer OS=Homo sapiens... 141 9e-33
sp|O42422|EPHA7_CHICK Ephrin type-A receptor 7 OS=Gallus gallus O... 141 1e-32
sp|O09127|EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus musculus OX... 141 1e-32
sp|P25020|SRC_RSVH1 Tyrosine-protein kinase transforming protein ... 137 1e-32
sp|P35590|TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 OS=Ho... 141 1e-32
sp|P00528|SRC64_DROME Tyrosine-protein kinase Src64B OS=Drosophil... 138 1e-32
sp|O73798|IGF1R_XENLA Insulin-like growth factor 1 receptor OS=Xe... 141 1e-32
sp|Q63474|DDR1_RAT Epithelial discoidin domain-containing recepto... 140 1e-32
sp|P08069|IGF1R_HUMAN Insulin-like growth factor 1 receptor OS=Ho... 141 1e-32
sp|Q13308|PTK7_HUMAN Inactive tyrosine-protein kinase 7 OS=Homo s... 141 1e-32
sp|P24062|IGF1R_RAT Insulin-like growth factor 1 receptor OS=Ratt... 141 2e-32
sp|Q15375|EPHA7_HUMAN Ephrin type-A receptor 7 OS=Homo sapiens OX... 140 2e-32
sp|P54759|EPHA7_RAT Ephrin type-A receptor 7 OS=Rattus norvegicus... 140 2e-32
sp|Q9VBW3|CAD96_DROME Tyrosine kinase receptor Cad96Ca OS=Drosoph... 139 2e-32
sp|Q06805|TIE1_BOVIN Tyrosine-protein kinase receptor Tie-1 OS=Bo... 140 2e-32
sp|Q60751|IGF1R_MOUSE Insulin-like growth factor 1 receptor OS=Mu... 141 2e-32
sp|Q8BKG3|PTK7_MOUSE Inactive tyrosine-protein kinase 7 OS=Mus mu... 140 2e-32
sp|P14617|INSRR_CAVPO Insulin receptor-related protein OS=Cavia p... 140 2e-32
sp|Q64434|PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus musculus OX... 134 4e-32
sp|P18106|FER_DROME Tyrosine-protein kinase Fer OS=Drosophila mel... 140 4e-32
sp|Q61772|EPHA7_MOUSE Ephrin type-A receptor 7 OS=Mus musculus OX... 139 4e-32
sp|P00541|FPS_AVISP Tyrosine-protein kinase transforming protein ... 135 5e-32
sp|Q9TTY2|FER_CANLF Tyrosine-protein kinase Fer OS=Canis lupus fa... 138 5e-32
sp|Q60805|MERTK_MOUSE Tyrosine-protein kinase Mer OS=Mus musculus... 139 6e-32
sp|Q91845|EPA4A_XENLA Ephrin type-A receptor 4-A OS=Xenopus laevi... 139 6e-32
sp|O73791|TIE2_DANRE Angiopoietin-1 receptor OS=Danio rerio OX=79... 139 6e-32
sp|Q07496|EPHA4_CHICK Ephrin type-A receptor 4 OS=Gallus gallus O... 139 7e-32
sp|Q60750|EPHA1_MOUSE Ephrin type-A receptor 1 OS=Mus musculus OX... 138 7e-32
sp|Q62838|MUSK_RAT Muscle, skeletal receptor tyrosine protein kin... 138 8e-32
sp|Q03137|EPHA4_MOUSE Ephrin type-A receptor 4 OS=Mus musculus OX... 138 1e-31
sp|Q03146|DDR1_MOUSE Epithelial discoidin domain-containing recep... 137 1e-31
sp|P54764|EPHA4_HUMAN Ephrin type-A receptor 4 OS=Homo sapiens OX... 137 1e-31
sp|P29322|EPHA8_HUMAN Ephrin type-A receptor 8 OS=Homo sapiens OX... 137 1e-31
sp|P00529|ROS_AVISU Tyrosine-protein kinase transforming protein ... 132 1e-31
sp|Q61006|MUSK_MOUSE Muscle, skeletal receptor tyrosine-protein k... 137 2e-31
sp|Q91694|EPA4B_XENLA Ephrin type-A receptor 4-B OS=Xenopus laevi... 137 2e-31
sp|H2KZU7|SVH2_CAEEL Tyrosine-protein kinase receptor svh-2 OS=Ca... 137 2e-31
sp|P08630|BTKL_DROME Tyrosine-protein kinase Btk OS=Drosophila me... 136 2e-31
sp|Q54I36|PYK3_DICDI Dual specificity protein kinase pyk3 OS=Dict... 137 3e-31
sp|P15127|INSR_RAT Insulin receptor OS=Rattus norvegicus OX=10116... 137 3e-31
sp|P15208|INSR_MOUSE Insulin receptor OS=Mus musculus OX=10090 GN... 137 3e-31
sp|P42687|SPK1_GIRTI Tyrosine-protein kinase SPK-1 OS=Girardia ti... 133 3e-31
sp|P57097|MERTK_RAT Tyrosine-protein kinase Mer OS=Rattus norvegi... 136 3e-31
sp|Q63132|ROS1_RAT Proto-oncogene tyrosine-protein kinase ROS OS=... 137 4e-31
sp|Q64716|INSRR_RAT Insulin receptor-related protein OS=Rattus no... 136 4e-31
sp|Q06187|BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo sapiens O... 134 4e-31
sp|P13368|7LESS_DROME Protein sevenless OS=Drosophila melanogaste... 137 4e-31
sp|Q25197|HTK7_HYDVU Putative insulin-like peptide receptor OS=Hy... 136 4e-31
sp|Q78DX7|ROS1_MOUSE Proto-oncogene tyrosine-protein kinase ROS O... 137 5e-31
sp|P09760|FER_RAT Tyrosine-protein kinase Fer OS=Rattus norvegicu... 135 5e-31
sp|P20806|7LESS_DROVI Protein sevenless OS=Drosophila virilis OX=... 137 5e-31
sp|Q9WTL4|INSRR_MOUSE Insulin receptor-related protein OS=Mus mus... 135 7e-31
sp|P70451|FER_MOUSE Tyrosine-protein kinase Fer OS=Mus musculus O... 135 7e-31
sp|P09208|INSR_DROME Insulin-like receptor OS=Drosophila melanoga... 136 7e-31
sp|G5EGK5|CAM1_CAEEL Tyrosine-protein kinase receptor cam-1 OS=Ca... 135 9e-31
sp|P14616|INSRR_HUMAN Insulin receptor-related protein OS=Homo sa... 135 1e-30
sp|Q05876|FYN_CHICK Tyrosine-protein kinase Fyn OS=Gallus gallus ... 132 1e-30
sp|Q10925|SID3_CAEEL Tyrosine-protein kinase sid-3 OS=Caenorhabdi... 134 2e-30
sp|P42681|TXK_HUMAN Tyrosine-protein kinase TXK OS=Homo sapiens O... 131 2e-30
sp|P00530|FPS_FUJSV Tyrosine-protein kinase transforming protein ... 134 2e-30
sp|Q6P6U0|FGR_RAT Tyrosine-protein kinase Fgr OS=Rattus norvegicu... 130 2e-30
sp|P00542|FES_FSVGA Tyrosine-protein kinase transforming protein ... 132 2e-30
sp|Q968Y9|INSR_CAEEL Insulin-like receptor OS=Caenorhabditis eleg... 134 3e-30
sp|P35991|BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus musculus O... 132 3e-30
sp|Q98949|TYRO3_CHICK Tyrosine-protein kinase receptor TYRO3 OS=G... 133 3e-30
sp|Q9Z139|ROR1_MOUSE Inactive tyrosine-protein kinase transmembra... 133 4e-30
sp|Q01973|ROR1_HUMAN Inactive tyrosine-protein kinase transmembra... 133 4e-30
sp|Q99ML2|TNK1_MOUSE Non-receptor tyrosine-protein kinase TNK1 OS... 131 4e-30
sp|P00543|FES_FSVST Tyrosine-protein kinase transforming protein ... 129 5e-30
sp|P14234|FGR_MOUSE Tyrosine-protein kinase Fgr OS=Mus musculus O... 129 6e-30
sp|G5EE56|SRC1_CAEEL Tyrosine protein-kinase src-1 OS=Caenorhabdi... 129 7e-30
sp|P42680|TEC_HUMAN Tyrosine-protein kinase Tec OS=Homo sapiens O... 130 8e-30
sp|Q13470|TNK1_HUMAN Non-receptor tyrosine-protein kinase TNK1 OS... 130 1e-29
sp|P08922|ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS O... 132 1e-29
sp|Q8CBF3|EPHB1_MOUSE Ephrin type-B receptor 1 OS=Mus musculus OX... 131 1e-29
sp|P09759|EPHB1_RAT Ephrin type-B receptor 1 OS=Rattus norvegicus... 131 1e-29
sp|P09769|FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo sapiens O... 128 1e-29
sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo sapiens OX... 131 2e-29
sp|Q91736|EPB1B_XENLA Ephrin type-B receptor 1-B (Fragment) OS=Xe... 130 2e-29
sp|Q91048|PTK7_CHICK Inactive tyrosine-protein kinase 7 OS=Gallus... 130 2e-29
sp|P14238|FES_FELCA Tyrosine-protein kinase Fes/Fps OS=Felis catu... 130 2e-29
sp|Q22146|FRK1_CAEEL Fer-related kinase 1 OS=Caenorhabditis elega... 125 3e-29
sp|Q8BYG9|EPHAA_MOUSE Ephrin type-A receptor 10 OS=Mus musculus O... 130 3e-29
sp|A0JM20|TYRO3_XENTR Tyrosine-protein kinase receptor TYRO3 OS=X... 130 3e-29
sp|P16591|FER_HUMAN Tyrosine-protein kinase Fer OS=Homo sapiens O... 129 3e-29
sp|Q91735|EPHB3_XENLA Ephrin type-B receptor 3 OS=Xenopus laevis ... 129 4e-29
sp|P24348|LET23_CAEEL Receptor tyrosine-protein kinase let-23 OS=... 130 4e-29
sp|Q2MHE4|HT1_ARATH Serine/threonine/tyrosine-protein kinase HT1 ... 124 4e-29
sp|Q9UF33|EPHA6_HUMAN Ephrin type-A receptor 6 OS=Homo sapiens OX... 129 6e-29
sp|P07332|FES_HUMAN Tyrosine-protein kinase Fes/Fps OS=Homo sapie... 129 6e-29
sp|Q07494|EPHB1_CHICK Ephrin type-B receptor 1 (Fragment) OS=Gall... 129 6e-29
sp|P54758|EPHA6_RAT Ephrin type-A receptor 6 OS=Rattus norvegicus... 129 6e-29
sp|P00544|FGR_FSVGR Tyrosine-protein kinase transforming protein ... 126 6e-29
sp|P24604|TEC_MOUSE Tyrosine-protein kinase Tec OS=Mus musculus O... 127 7e-29
sp|Q19238|YS3J_CAEEL Putative tyrosine-protein kinase F09A5.2 OS=... 128 7e-29
sp|P54763|EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus musculus OX... 129 7e-29
sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens OX... 129 9e-29
sp|P55146|TYRO3_RAT Tyrosine-protein kinase receptor TYRO3 OS=Rat... 128 9e-29
sp|Q13882|PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo sapiens OX... 124 1e-28
sp|P28693|EPHB2_CHICK Ephrin type-B receptor 2 OS=Gallus gallus O... 128 1e-28
sp|P29376|LTK_HUMAN Leukocyte tyrosine kinase receptor OS=Homo sa... 127 1e-28
sp|Q8JH64|BTK_CHICK Tyrosine-protein kinase BTK OS=Gallus gallus ... 126 1e-28
sp|Q62413|EPHA6_MOUSE Ephrin type-A receptor 6 OS=Mus musculus OX... 128 2e-28
sp|P55144|TYRO3_MOUSE Tyrosine-protein kinase receptor TYRO3 OS=M... 127 2e-28
sp|D2IYS2|TORSO_BOMMO Tyrosine-protein kinase receptor torso OS=B... 127 2e-28
sp|P16879|FES_MOUSE Tyrosine-protein kinase Fes/Fps OS=Mus muscul... 127 2e-28
sp|P08941|ROS1_CHICK Proto-oncogene tyrosine-protein kinase ROS O... 128 2e-28
sp|Q06418|TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3 OS=H... 127 2e-28
sp|Q90344|EPHB2_COTJA Ephrin type-B receptor 2 OS=Coturnix japoni... 127 2e-28
sp|Q54TM7|DRKD_DICDI Probable serine/threonine-protein kinase drk... 127 3e-28
sp|Q8QFP9|TYRO3_XENLA Tyrosine-protein kinase receptor TYRO3 OS=X... 126 4e-28
sp|Q03526|ITK_MOUSE Tyrosine-protein kinase ITK/TSK OS=Mus muscul... 125 4e-28
sp|P18475|TORSO_DROME Tyrosine-protein kinase receptor torso OS=D... 126 4e-28
sp|Q01887|RYK_MOUSE Tyrosine-protein kinase RYK OS=Mus musculus O... 124 5e-28
sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kinas... 125 5e-28
sp|Q91571|EPB1A_XENLA Ephrin type-B receptor 1-A OS=Xenopus laevi... 126 5e-28
sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase kin... 125 5e-28
sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kin... 125 6e-28
sp|O13147|EPHB3_DANRE Ephrin type-B receptor 3 (Fragment) OS=Dani... 122 7e-28
sp|Q9I8N6|CSF1R_DANRE Macrophage colony-stimulating factor 1 rece... 125 8e-28
sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens OX... 125 8e-28
sp|O73878|EPB4B_DANRE Ephrin type-B receptor 4b OS=Danio rerio OX... 125 1e-27
sp|P30530|UFO_HUMAN Tyrosine-protein kinase receptor UFO OS=Homo ... 125 1e-27
sp|O73792|TIE1_DANRE Tyrosine-protein kinase receptor Tie-1 (Frag... 114 1e-27
sp|P97793|ALK_MOUSE ALK tyrosine kinase receptor OS=Mus musculus ... 125 1e-27
sp|Q5JZY3|EPHAA_HUMAN Ephrin type-A receptor 10 OS=Homo sapiens O... 124 1e-27
sp|O73875|EPB4A_DANRE Ephrin type-B receptor 4a OS=Danio rerio OX... 124 1e-27
sp|P08923|LTK_MOUSE Leukocyte tyrosine kinase receptor OS=Mus mus... 124 1e-27
sp|P54761|EPHB4_MOUSE Ephrin type-B receptor 4 OS=Mus musculus OX... 124 2e-27
sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kina... 123 2e-27
sp|Q00993|UFO_MOUSE Tyrosine-protein kinase receptor UFO OS=Mus m... 124 2e-27
sp|P34925|RYK_HUMAN Tyrosine-protein kinase RYK OS=Homo sapiens O... 122 2e-27
sp|Q07497|EPHB5_CHICK Ephrin type-B receptor 5 OS=Gallus gallus O... 124 2e-27
sp|Q9UM73|ALK_HUMAN ALK tyrosine kinase receptor OS=Homo sapiens ... 124 2e-27
sp|Q61084|M3K3_MOUSE Mitogen-activated protein kinase kinase kina... 122 2e-27
sp|P0DV84|ALK_CANLF ALK tyrosine kinase receptor OS=Canis lupus f... 124 2e-27
sp|P80192|M3K9_HUMAN Mitogen-activated protein kinase kinase kina... 124 3e-27
sp|O22558|STY8_ARATH Serine/threonine-protein kinase STY8 OS=Arab... 120 5e-27
sp|Q66L42|M3K10_MOUSE Mitogen-activated protein kinase kinase kin... 122 6e-27
sp|P04048|KIT_FSVHZ Tyrosine-protein kinase transforming protein ... 117 6e-27
sp|P54753|EPHB3_HUMAN Ephrin type-B receptor 3 OS=Homo sapiens OX... 122 7e-27
sp|Q08881|ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=Homo sapie... 121 7e-27
sp|Q3U1V8|M3K9_MOUSE Mitogen-activated protein kinase kinase kina... 122 9e-27
sp|P54754|EPHB3_MOUSE Ephrin type-B receptor 3 OS=Mus musculus OX... 122 9e-27
sp|D3ZG83|M3K10_RAT Mitogen-activated protein kinase kinase kinas... 122 9e-27
sp|Q07498|EPHB3_CHICK Ephrin type-B receptor 3 (Fragment) OS=Gall... 122 1e-26
sp|Q21038|VER3_CAEEL Tyrosine-protein kinase receptor ver-3 OS=Ca... 122 1e-26
sp|Q17833|OLD1_CAEEL Tyrosine-protein kinase receptor old-1 OS=Ca... 119 2e-26
sp|F4JTP5|STY46_ARATH Serine/threonine-protein kinase STY46 OS=Ar... 119 2e-26
sp|P34892|KIN16_CAEEL Receptor-like tyrosine-protein kinase kin-1... 118 2e-26
sp|Q5XF79|PBL18_ARATH Probable serine/threonine-protein kinase PB... 116 3e-26
sp|Q02779|M3K10_HUMAN Mitogen-activated protein kinase kinase kin... 120 3e-26
sp|Q01974|ROR2_HUMAN Tyrosine-protein kinase transmembrane recept... 120 3e-26
sp|Q54PX0|Y4251_DICDI Probable serine/threonine-protein kinase DD... 117 6e-26
sp|Q08156|KIT_CHICK Mast/stem cell growth factor receptor Kit OS=... 119 7e-26
sp|Q9Z138|ROR2_MOUSE Tyrosine-protein kinase transmembrane recept... 119 8e-26
sp|Q9V6K3|ROR2_DROME Tyrosine-protein kinase transmembrane recept... 117 1e-25
sp|O76411|SCD2_CAEEL ALK tyrosine kinase receptor homolog scd-2 O... 118 2e-25
sp|Q28889|KIT_FELCA Mast/stem cell growth factor receptor Kit OS=... 117 2e-25
sp|P43481|KIT_BOVIN Mast/stem cell growth factor receptor Kit OS=... 117 2e-25
sp|Q28317|KIT_CAPHI Mast/stem cell growth factor receptor Kit OS=... 117 2e-25
sp|O97799|KIT_CANLF Mast/stem cell growth factor receptor Kit OS=... 117 2e-25
sp|Q2HWD6|KIT_PIG Mast/stem cell growth factor receptor Kit OS=Su... 117 3e-25
sp|G4N7X0|MST11_PYRO7 Mitogen-activated protein kinase kinae kina... 117 3e-25
sp|P10721|KIT_HUMAN Mast/stem cell growth factor receptor Kit OS=... 117 3e-25
sp|Q76II0|KIT_CALJA Mast/stem cell growth factor receptor Kit OS=... 117 3e-25
sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kina... 115 3e-25
sp|P05532|KIT_MOUSE Mast/stem cell growth factor receptor Kit OS=... 117 4e-25
sp|O61460|VAB1_CAEEL Ephrin receptor 1 OS=Caenorhabditis elegans ... 117 4e-25
sp|Q8RWL6|STY17_ARATH Serine/threonine-protein kinase STY17 OS=Ar... 115 4e-25
sp|F8W3R9|ALK_DANRE ALK tyrosine kinase receptor OS=Danio rerio O... 117 5e-25
sp|P00545|KFMS_FSVMD Tyrosine-protein kinase transforming protein... 116 5e-25
sp|Q5MD89|VGFR3_DANRE Vascular endothelial growth factor receptor... 117 5e-25
sp|A9SY39|M3K1A_PHYPA Mitogen-activated protein kinase kinase kin... 115 5e-25
sp|P13369|CSF1R_FELCA Macrophage colony-stimulating factor 1 rece... 115 8e-25
sp|P07333|CSF1R_HUMAN Macrophage colony-stimulating factor 1 rece... 115 8e-25
sp|P42159|RTK2_GEOCY Class II receptor tyrosine kinase OS=Geodia ... 114 9e-25
sp|Q9FGB1|CBC2_ARATH Serine/threonine-protein kinase 52 OS=Arabid... 111 9e-25
sp|Q55GU0|Y9955_DICDI Probable serine/threonine-protein kinase DD... 115 9e-25
sp|Q5PP29|PBL4_ARATH Probable serine/threonine-protein kinase PBL... 112 9e-25
sp|Q9ZQ31|STY13_ARATH Serine/threonine-protein kinase STY13 OS=Ar... 111 2e-24
sp|Q9ESL4|M3K20_MOUSE Mitogen-activated protein kinase kinase kin... 114 2e-24
sp|Q9SFB6|M3KE2_ARATH MAP3K epsilon protein kinase 2 OS=Arabidops... 115 2e-24
sp|Q9NYL2|M3K20_HUMAN Mitogen-activated protein kinase kinase kin... 114 2e-24
sp|F1QVU0|LTK_DANRE Tyrosine-protein kinase receptor OS=Danio rer... 115 2e-24
sp|Q91909|KIT_XENLA Mast/stem cell growth factor receptor-related... 114 2e-24
sp|Q7T2V3|M3K10_XENLA Mitogen-activated protein kinase kinase kin... 114 3e-24
sp|Q00495|CSF1R_RAT Macrophage colony-stimulating factor 1 recept... 114 3e-24
sp|P27450|CST_ARATH Probable serine/threonine-protein kinase CST ... 110 3e-24
sp|Q9LJD8|M3KE1_ARATH MAP3K epsilon protein kinase 1 OS=Arabidops... 114 3e-24
sp|P09581|CSF1R_MOUSE Macrophage colony-stimulating factor 1 rece... 113 4e-24
sp|P35968|VGFR2_HUMAN Vascular endothelial growth factor receptor... 114 4e-24
sp|Q8AXC6|KIT_TAKRU Mast/stem cell growth factor receptor Kit OS=... 113 5e-24
sp|Q21041|VER4_CAEEL Tyrosine-protein kinase receptor ver-4 OS=Ca... 113 5e-24
sp|Q8JFR5|KITA_DANRE Mast/stem cell growth factor receptor kita O... 113 6e-24
sp|Q8UVR8|CSF12_TAKRU Macrophage colony-stimulating factor 1 rece... 113 6e-24
sp|Q5XJV6|LMTK3_MOUSE Serine/threonine-protein kinase LMTK3 OS=Mu... 113 7e-24
sp|A0A078CGE6|M3KE1_BRANA MAP3K epsilon protein kinase 1 OS=Brass... 113 8e-24
sp|P34891|KIN15_CAEEL Receptor-like tyrosine-protein kinase kin-1... 110 8e-24
sp|Q9SSA4|CBC1_ARATH Serine/threonine-protein kinase 54 OS=Arabid... 108 1e-23
sp|Q65XV8|RK176_ORYSJ Receptor-like cytoplasmic kinase 176 OS=Ory... 108 1e-23
sp|Q54R82|MKKA_DICDI Mitogen-activated protein kinase kinase kina... 112 1e-23
sp|F4HRJ4|M3K3A_ARATH Mitogen-activated protein kinase kinase kin... 110 2e-23
sp|Q95UN8|M3KSL_DROME Mitogen-activated protein kinase kinase kin... 112 2e-23
sp|Q8AXB3|VGFR4_DANRE Vascular endothelial growth factor receptor... 111 2e-23
sp|Q0CL79|SEPH_ASPTN Cytokinesis protein sepH OS=Aspergillus terr... 111 2e-23
sp|Q9FZ36|M3K2_ARATH Mitogen-activated protein kinase kinase kina... 110 2e-23
sp|Q61083|M3K2_MOUSE Mitogen-activated protein kinase kinase kina... 110 2e-23
sp|Q96Q04|LMTK3_HUMAN Serine/threonine-protein kinase LMTK3 OS=Ho... 111 2e-23
sp|Q54Y55|SHKC_DICDI Dual specificity protein kinase shkC OS=Dict... 108 3e-23
sp|P52583|VGFR2_COTJA Vascular endothelial growth factor receptor... 111 3e-23
sp|P41892|CDC7_SCHPO Cell division control protein 7 OS=Schizosac... 110 3e-23
sp|Q9ASQ5|CRCK3_ARATH Calmodulin-binding receptor-like cytoplasmi... 108 4e-23
sp|Q40541|NPK1_TOBAC Mitogen-activated protein kinase kinase kina... 109 4e-23
sp|P28829|BYR2_SCHPO Protein kinase byr2 OS=Schizosaccharomyces p... 109 4e-23
sp|P79750|CSF11_TAKRU Macrophage colony-stimulating factor 1 rece... 110 5e-23
sp|Q9PUF6|PGFRA_CHICK Platelet-derived growth factor receptor alp... 109 7e-23
sp|P35918|VGFR2_MOUSE Vascular endothelial growth factor receptor... 109 1e-22
sp|Q8VDG6|M3K21_MOUSE Mitogen-activated protein kinase kinase kin... 108 1e-22
sp|P79701|VGFR3_COTCO Vascular endothelial growth factor receptor... 109 1e-22
sp|P20786|PGFRA_RAT Platelet-derived growth factor receptor alpha... 108 1e-22
sp|Q9CAD5|YODA_ARATH Mitogen-activated protein kinase kinase kina... 108 1e-22
sp|P26618|PGFRA_MOUSE Platelet-derived growth factor receptor alp... 108 2e-22
sp|P16234|PGFRA_HUMAN Platelet-derived growth factor receptor alp... 108 2e-22
sp|Q39008|M3K1_ARATH Mitogen-activated protein kinase kinase kina... 107 2e-22
sp|H2L099|GCK1_CAEEL Germinal center kinase 1 OS=Caenorhabditis e... 107 3e-22
sp|E9Q3S4|M3K19_MOUSE Mitogen-activated protein kinase kinase kin... 108 3e-22
sp|A0A0K3AV08|MLK1_CAEEL Mitogen-activated protein kinase kinase ... 107 3e-22
sp|Q13546|RIPK1_HUMAN Receptor-interacting serine/threonine-prote... 106 3e-22
sp|O64842|PBL12_ARATH Probable serine/threonine-protein kinase PB... 104 3e-22
sp|Q9LTC0|PBL19_ARATH Probable serine/threonine-protein kinase PB... 104 3e-22
sp|P26619|PGFRA_XENLA Platelet-derived growth factor receptor alp... 107 4e-22
sp|P36888|FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 O... 107 4e-22
sp|Q5TCX8|M3K21_HUMAN Mitogen-activated protein kinase kinase kin... 107 4e-22
sp|Q9LFP7|PBL34_ARATH Serine/threonine-protein kinase PBL34 OS=Ar... 105 5e-22
sp|A2QHV0|SEPH_ASPNC Cytokinesis protein sepH OS=Aspergillus nige... 107 5e-22
sp|Q54RR9|Y9844_DICDI Probable serine/threonine-protein kinase DD... 107 6e-22
sp|Q8AXC7|PGFRA_TAKRU Platelet-derived growth factor receptor alp... 106 6e-22
sp|Q8VYG0|LRL13_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 105 6e-22
sp|Q5GIT4|VGFR2_DANRE Vascular endothelial growth factor receptor... 107 6e-22
sp|Q8IR79|LIMK1_DROME LIM domain kinase 1 OS=Drosophila melanogas... 106 8e-22
sp|O14047|PPK11_SCHPO Serine/threonine-protein kinase ppk11 OS=Sc... 101 8e-22
sp|Q8QHL3|VGFR1_CHICK Vascular endothelial growth factor receptor... 106 1e-21
sp|Q54RZ7|Y1199_DICDI Probable serine/threonine-protein kinase DD... 106 1e-21
sp|Q5B4Z3|SEPH_EMENI Cytokinesis protein sepH OS=Emericella nidul... 106 1e-21
sp|Q9SRH7|PBL35_ARATH Serine/threonine-protein kinase PBL35 OS=Ar... 103 1e-21
sp|P53767|VGFR1_RAT Vascular endothelial growth factor receptor 1... 105 1e-21
sp|O22042|M3K3_ARATH Mitogen-activated protein kinase kinase kina... 104 1e-21
sp|P35969|VGFR1_MOUSE Vascular endothelial growth factor receptor... 105 1e-21
sp|O01798|SPE8_CAEEL Spermatocyte protein spe-8 OS=Caenorhabditis... 103 1e-21
sp|Q55A09|Y9963_DICDI Probable serine/threonine-protein kinase DD... 105 1e-21
sp|P10533|RMIL_AVII1 Serine/threonine-protein kinase-transforming... 101 1e-21
sp|Q4WXY0|BCK1_ASPFU Mitogen-activated protein kinase kinae kinas... 105 2e-21
sp|Q8I7I5|ROL3_CAEEL Protein roller-3 OS=Caenorhabditis elegans O... 105 2e-21
sp|B0XXN8|BCK1_ASPFC Mitogen-activated protein kinase kinae kinas... 105 2e-21
sp|Q9DE49|PGFRA_DANRE Platelet-derived growth factor receptor alp... 105 2e-21
sp|P23561|STE11_YEAST Serine/threonine-protein kinase STE11 OS=Sa... 104 2e-21
sp|A7A1P0|STE11_YEAS7 Serine/threonine-protein kinase STE11 OS=Sa... 104 2e-21
sp|Q61846|MELK_MOUSE Maternal embryonic leucine zipper kinase OS=... 103 2e-21
sp|Q54H45|DRKB_DICDI Probable serine/threonine-protein kinase drk... 104 2e-21
sp|O24527|SIK1_ARATH Serine/threonine-protein kinase 1 OS=Arabido... 104 2e-21
sp|O08775|VGFR2_RAT Vascular endothelial growth factor receptor 2... 105 2e-21
sp|Q54RB7|SHKA_DICDI Dual specificity protein kinase shkA OS=Dict... 103 2e-21
sp|P35917|VGFR3_MOUSE Vascular endothelial growth factor receptor... 104 3e-21
sp|Q91ZT1|VGFR3_RAT Vascular endothelial growth factor receptor 3... 104 3e-21
sp|Q10056|SHK2_SCHPO Serine/threonine-protein kinase shk2 OS=Schi... 103 3e-21
sp|Q55FT4|TSUA_DICDI Probable serine/threonine-protein kinase tsu... 105 3e-21
sp|P27636|CDC15_YEAST Cell division control protein 15 OS=Sacchar... 104 3e-21
sp|Q00342|FLT3_MOUSE Receptor-type tyrosine-protein kinase FLT3 O... 104 3e-21
sp|P00532|RAF_MSV36 Serine/threonine-protein kinase-transforming ... 99.8 3e-21
sp|F4JPX3|PBL20_ARATH Probable serine/threonine-protein kinase PB... 100 3e-21
sp|B5VNQ3|STE11_YEAS6 Serine/threonine-protein kinase STE11 OS=Sa... 103 3e-21
sp|Q9SII6|PIX13_ARATH Probable serine/threonine-protein kinase PI... 101 4e-21
sp|Q12852|M3K12_HUMAN Mitogen-activated protein kinase kinase kin... 103 4e-21
sp|Q60700|M3K12_MOUSE Mitogen-activated protein kinase kinase kin... 103 4e-21
sp|P17948|VGFR1_HUMAN Vascular endothelial growth factor receptor... 104 4e-21
sp|A7J1T2|M313A_XENLA Mitogen-activated protein kinase kinase kin... 103 4e-21
sp|P00531|MIL_AVIMH Serine/threonine-protein kinase-transforming ... 100 4e-21
sp|Q8GXZ3|PBL8_ARATH Probable serine/threonine-protein kinase PBL... 100 5e-21
sp|P11346|KRAF1_DROME Raf homolog serine/threonine-protein kinase... 103 5e-21
sp|O22040|ANP1_ARATH Mitogen-activated protein kinase kinase kina... 102 6e-21
sp|Q7T6Y2|YR831_MIMIV Putative serine/threonine-protein kinase/re... 103 6e-21
sp|A7J1T0|M313B_XENLA Mitogen-activated protein kinase kinase kin... 103 6e-21
sp|P27966|RMIL_AVEVR Serine/threonine-protein kinase-transforming... 100 6e-21
sp|G4NDR3|MCK1_PYRO7 Mitogen-activated protein kinase kinae kinas... 103 7e-21
sp|O49840|PBL3_ARATH Probable serine/threonine-protein kinase PBL... 100 7e-21
sp|Q06548|PBL9_ARATH Probable serine/threonine-protein kinase PBL... 100 7e-21
sp|Q54TA3|MRKC_DICDI Probable serine/threonine-protein kinase MAR... 102 9e-21
sp|Q9C9U5|SIS8_ARATH Probable serine/threonine-protein kinase SIS... 102 9e-21
sp|F4J0D2|PBL36_ARATH Serine/threonine-protein kinase PBL36 OS=Ar... 100 1e-20
sp|Q9LPQ3|M2K7_ARATH Mitogen-activated protein kinase kinase 7 OS... 97.8 1e-20
sp|Q63796|M3K12_RAT Mitogen-activated protein kinase kinase kinas... 102 1e-20
sp|O48814|BIK1_ARATH Serine/threonine-protein kinase BIK1 OS=Arab... 99.4 1e-20
sp|Q8IWU2|LMTK2_HUMAN Serine/threonine-protein kinase LMTK2 OS=Ho... 102 1e-20
sp|O81472|MP3K2_ARATH Mitogen-activated protein kinase kinase kin... 102 1e-20
sp|Q9UL54|TAOK2_HUMAN Serine/threonine-protein kinase TAO2 OS=Hom... 102 1e-20
sp|Q56UN5|M3K19_HUMAN Mitogen-activated protein kinase kinase kin... 102 1e-20
sp|P11345|RAF1_RAT RAF proto-oncogene serine/threonine-protein ki... 101 1e-20
sp|Q869T7|PAKF_DICDI Serine/threonine-protein kinase pakF OS=Dict... 102 2e-20
sp|P05625|RAF1_CHICK RAF proto-oncogene serine/threonine-protein ... 101 2e-20
sp|Q6ZQ29|TAOK2_MOUSE Serine/threonine-protein kinase TAO2 OS=Mus... 102 2e-20
sp|Q5R5M7|RAF1_PONAB RAF proto-oncogene serine/threonine-protein ... 100 2e-20
sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein ... 100 2e-20
sp|Q9C5H5|M3K5G_ARATH Mitogen-activated protein kinase kinase kin... 101 2e-20
sp|A7MBB4|M3K13_BOVIN Mitogen-activated protein kinase kinase kin... 101 2e-20
sp|Q54JG7|DST4_DICDI Serine/threonine-protein kinase dst4 OS=Dict... 99.8 2e-20
sp|Q9JLS3|TAOK2_RAT Serine/threonine-protein kinase TAO2 OS=Rattu... 101 2e-20
sp|P20792|DAF1_CAEEL Cell surface receptor daf-1 OS=Caenorhabditi... 100 3e-20
sp|Q1HKZ5|M3K13_MOUSE Mitogen-activated protein kinase kinase kin... 101 3e-20
sp|Q54XQ2|RCKA_DICDI RGS domain-containing serine/threonine-prote... 101 3e-20
sp|O14305|SID1_SCHPO Serine/threonine-protein kinase sid1 OS=Schi... 99.4 3e-20
sp|P43293|PBL11_ARATH Probable serine/threonine-protein kinase PB... 98.2 3e-20
sp|A7E3S4|RAF1_BOVIN RAF proto-oncogene serine/threonine-protein ... 100 3e-20
sp|Q54TA1|DRKC_DICDI Probable serine/threonine-protein kinase drk... 100 3e-20
sp|P23437|CDK2_XENLA Cyclin-dependent kinase 2 OS=Xenopus laevis ... 96.3 3e-20
sp|Q9SZ67|WRK19_ARATH Probable WRKY transcription factor 19 OS=Ar... 101 3e-20
sp|Q6GPK9|TAOK2_XENLA Serine/threonine-protein kinase TAO2 OS=Xen... 100 3e-20
sp|O61125|STK4_DICDI Serine/threonine-protein kinase 4 homolog A ... 99.0 3e-20
sp|P79749|PGFRB_TAKRU Platelet-derived growth factor receptor bet... 100 4e-20
sp|Q9Z2W1|STK25_MOUSE Serine/threonine-protein kinase 25 OS=Mus m... 98.2 4e-20
sp|Q5UQG7|YR818_MIMIV Putative serine/threonine-protein kinase/re... 101 4e-20
sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Hom... 100 4e-20
sp|O49839|PBL2_ARATH Probable serine/threonine-protein kinase PBL... 98.2 4e-20
sp|Q6QNF3|PGFRB_CANLF Platelet-derived growth factor receptor bet... 100 4e-20
sp|Q9XI96|PERK7_ARATH Proline-rich receptor-like protein kinase P... 100 4e-20
sp|P35916|VGFR3_HUMAN Vascular endothelial growth factor receptor... 100 4e-20
sp|Q9SY91|PBL15_ARATH Probable serine/threonine-protein kinase PB... 98.2 4e-20
sp|O43283|M3K13_HUMAN Mitogen-activated protein kinase kinase kin... 100 4e-20
sp|P28028|BRAF_MOUSE Serine/threonine-protein kinase B-raf OS=Mus... 100 4e-20
sp|Q04982|BRAF_CHICK Serine/threonine-protein kinase B-raf OS=Gal... 100 5e-20
sp|Q8T2I8|SEPA_DICDI Serine/threonine-protein kinase sepA OS=Dict... 100 5e-20
sp|P34908|BRAF_COTJA Serine/threonine-protein kinase B-raf OS=Cot... 100 5e-20
sp|Q9C6K9|LRL11_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 99.8 5e-20
sp|Q5R8X7|M3K13_PONAB Mitogen-activated protein kinase kinase kin... 100 5e-20
sp|C0LGQ7|Y4245_ARATH Probable LRR receptor-like serine/threonine... 100 5e-20
sp|Q9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 OS=Homo ... 98.2 5e-20
sp|Q80YP0|CDK3_MOUSE Cyclin-dependent kinase 3 OS=Mus musculus OX... 95.9 5e-20
sp|Q99N57|RAF1_MOUSE RAF proto-oncogene serine/threonine-protein ... 99.8 5e-20
sp|Q84M95|PBL28_ARATH Probable serine/threonine-protein kinase PB... 97.1 5e-20
sp|B0LT89|STK24_RAT Serine/threonine-protein kinase 24 OS=Rattus ... 97.8 5e-20
sp|Q3SWY6|STK25_BOVIN Serine/threonine-protein kinase 25 OS=Bos t... 97.8 5e-20
sp|Q99KH8|STK24_MOUSE Serine/threonine-protein kinase 24 OS=Mus m... 97.8 5e-20
sp|Q869X3|Y9851_DICDI Probable serine/threonine-protein kinase DD... 100 6e-20
sp|Q9XI87|VIK_ARATH Serine/threonine-protein kinase VIK OS=Arabid... 97.8 6e-20
sp|F1NBT0|STK10_CHICK Serine/threonine-protein kinase 10 OS=Gallu... 100 6e-20
sp|G5ED65|VER1_CAEEL Protein ver-1 OS=Caenorhabditis elegans OX=6... 100 6e-20
sp|Q9LDZ5|PBL21_ARATH Probable serine/threonine-protein kinase PB... 97.1 6e-20
sp|Q9SF86|PCRK1_ARATH Serine/threonine-protein kinase PCRK1 OS=Ar... 97.4 6e-20
sp|P09619|PGFRB_HUMAN Platelet-derived growth factor receptor bet... 100 7e-20
sp|Q55CA6|Y0146_DICDI Probable serine/threonine-protein kinase DD... 99.4 7e-20
sp|Q7ZYJ0|TAO1B_XENLA Serine/threonine-protein kinase TAO1-B OS=X... 100 7e-20
sp|Q55EC7|GEFX_DICDI RasGEF domain-containing serine/threonine-pr... 99.8 8e-20
sp|Q05030|PGFRB_RAT Platelet-derived growth factor receptor beta ... 99.8 8e-20
sp|Q91821|MELK_XENLA Maternal embryonic leucine zipper kinase OS=... 99.0 8e-20
sp|Q28GW8|MELK_XENTR Maternal embryonic leucine zipper kinase OS=... 99.0 9e-20
sp|P05622|PGFRB_MOUSE Platelet-derived growth factor receptor bet... 99.8 9e-20
sp|Q9SFT7|PBL26_ARATH Probable serine/threonine-protein kinase PB... 97.1 9e-20
sp|O61122|SVKA_DICDI Serine/threonine-protein kinase svkA OS=Dict... 97.8 9e-20
sp|F4HQ17|LRL14_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 99.0 9e-20
sp|Q9P289|STK26_HUMAN Serine/threonine-protein kinase 26 OS=Homo ... 97.1 1e-19
sp|Q9FPR3|EDR1_ARATH Serine/threonine-protein kinase EDR1 OS=Arab... 99.4 1e-19
sp|Q924U5|TESK2_RAT Dual specificity testis-specific protein kina... 98.2 1e-19
sp|Q55E58|PATS1_DICDI Probable serine/threonine-protein kinase pa... 100 1e-19
sp|Q99JT2|STK26_MOUSE Serine/threonine-protein kinase 26 OS=Mus m... 96.7 1e-19
sp|Q7T6X2|YR826_MIMIV Putative serine/threonine-protein kinase/re... 99.8 1e-19
sp|O00506|STK25_HUMAN Serine/threonine-protein kinase 25 OS=Homo ... 97.1 1e-19
sp|Q9ZUF4|RIPK_ARATH Serine/threonine-protein kinase RIPK OS=Arab... 97.1 1e-19
sp|P09560|RAF1_XENLA RAF proto-oncogene serine/threonine-protein ... 98.2 1e-19
sp|P18160|SPLA_DICDI Dual specificity protein kinase splA OS=Dict... 99.4 1e-19
sp|Q23915|KINX_DICDI Probable serine/threonine-protein kinase kin... 99.0 1e-19
sp|Q54VC0|Y9865_DICDI Probable serine/threonine-protein kinase DD... 96.3 2e-19
sp|Q8VCT9|TESK2_MOUSE Dual specificity testis-specific protein ki... 97.4 2e-19
sp|A8WYE4|PAR1_CAEBR Serine/threonine-protein kinase par-1 OS=Cae... 98.6 2e-19
sp|P53670|LIMK2_RAT LIM domain kinase 2 OS=Rattus norvegicus OX=1... 97.8 2e-19
sp|Q9TW45|PAR1_CAEEL Serine/threonine-protein kinase par-1 OS=Cae... 98.6 2e-19
sp|B4MR28|PTK7_DROWI Tyrosine-protein kinase-like otk OS=Drosophi... 98.6 2e-19
sp|Q86AT8|SPKA_DICDI Stress-activated protein kinase alpha OS=Dic... 97.8 2e-19
sp|O54785|LIMK2_MOUSE LIM domain kinase 2 OS=Mus musculus OX=1009... 97.4 3e-19
sp|P32562|CDC5_YEAST Cell cycle serine/threonine-protein kinase C... 97.4 3e-19
sp|Q9I9E0|TAOK3_CHICK Serine/threonine-protein kinase TAO3 OS=Gal... 97.8 3e-19
sp|Q55EI8|Y9956_DICDI Probable serine/threonine-protein kinase DD... 98.2 3e-19
sp|Q0WRY5|PBL7_ARATH Probable serine/threonine-protein kinase PBL... 94.7 3e-19
sp|Q14680|MELK_HUMAN Maternal embryonic leucine zipper kinase OS=... 97.4 3e-19
sp|Q27324|RYK1_DROME Tyrosine-protein kinase Drl OS=Drosophila me... 97.1 3e-19
sp|Q86HG9|Y9871_DICDI Probable serine/threonine-protein kinase DD... 97.8 3e-19
sp|Q8RWW0|ALE2_ARATH Receptor-like serine/threonine-protein kinas... 97.4 3e-19
sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapiens OX=9606... 97.1 4e-19
sp|Q9ZNQ8|PERK4_ARATH Proline-rich receptor-like protein kinase P... 96.7 4e-19
sp|Q9CAL8|PEK13_ARATH Proline-rich receptor-like protein kinase P... 97.1 4e-19
sp|F1QGZ6|MELK_DANRE Maternal embryonic leucine zipper kinase OS=... 96.7 4e-19
sp|Q10407|MKH1_SCHPO MAP kinase kinase kinase mkh1 OS=Schizosacch... 97.4 4e-19
sp|Q6DD27|TAOK3_XENLA Serine/threonine-protein kinase TAO3 OS=Xen... 97.4 4e-19
sp|Q8H186|PBL1_ARATH Probable serine/threonine-protein kinase PBL... 94.4 4e-19
sp|A9RVK2|M3K1B_PHYPA Mitogen-activated protein kinase kinase kin... 97.1 5e-19
sp|Q32L23|LIMK2_BOVIN LIM domain kinase 2 OS=Bos taurus OX=9913 G... 96.7 5e-19
sp|A6ZU08|TOS3_YEAS7 Serine/threonine-protein kinase TOS3 OS=Sacc... 95.9 5e-19
sp|C0LGD7|Y1684_ARATH Probable LRR receptor-like serine/threonine... 97.1 5e-19
sp|P43637|TOS3_YEAST Serine/threonine-protein kinase TOS3 OS=Sacc... 95.9 6e-19
sp|Q6NU21|TAO1A_XENLA Serine/threonine-protein kinase TAO1-A OS=X... 97.1 6e-19
sp|Q9LZF8|PCRK2_ARATH Serine/threonine-protein kinase PCRK2 OS=Ar... 94.7 6e-19
sp|P52497|SNF1_CANAX Carbon catabolite-derepressing protein kinas... 96.3 6e-19
sp|Q3TYD6|LMTK2_MOUSE Serine/threonine-protein kinase LMTK2 OS=Mu... 97.1 6e-19
sp|F4IS56|ILK1_ARATH Integrin-linked protein kinase 1 OS=Arabidop... 95.1 6e-19
sp|Q5R4F3|TAOK3_PONAB Serine/threonine-protein kinase TAO3 OS=Pon... 96.7 6e-19
sp|Q9M0T3|MP3K3_ARATH Mitogen-activated protein kinase kinase kin... 95.9 6e-19
sp|Q54DF2|MRKA_DICDI Probable serine/threonine-protein kinase MAR... 97.1 7e-19
sp|P08458|SPS1_YEAST Sporulation-specific protein 1 OS=Saccharomy... 95.1 7e-19
sp|P43298|TMK1_ARATH Receptor protein kinase TMK1 OS=Arabidopsis ... 96.7 7e-19
sp|Q0IHQ8|STK10_XENTR Serine/threonine-protein kinase 10 OS=Xenop... 96.7 7e-19
sp|Q8R4K2|IRAK4_MOUSE Interleukin-1 receptor-associated kinase 4 ... 94.7 7e-19
sp|H2KZW3|M3K20_CAEEL Mitogen-activated protein kinase kinase kin... 96.3 7e-19
sp|Q8GX23|PERK5_ARATH Proline-rich receptor-like protein kinase P... 95.9 8e-19
sp|P53666|LIMK2_CHICK LIM domain kinase 2 OS=Gallus gallus OX=903... 95.9 8e-19
sp|P53668|LIMK1_MOUSE LIM domain kinase 1 OS=Mus musculus OX=1009... 95.9 8e-19
sp|A4K2M3|STK4_PAPAN Serine/threonine-protein kinase 4 OS=Papio a... 94.7 9e-19
sp|Q54R58|YTYK2_DICDI Probable tyrosine-protein kinase DDB_G02833... 95.9 1e-18
sp|Q9LRY1|PBL25_ARATH Probable serine/threonine-protein kinase PB... 93.2 1e-18
sp|G4NEB8|MST7_PYRO7 Mitogen-activated protein kinase kinae MST7 ... 93.6 1e-18
sp|A4K2W5|STK4_AOTNA Serine/threonine-protein kinase 4 OS=Aotus n... 94.4 1e-18
sp|Q86I06|NEK3_DICDI Probable serine/threonine-protein kinase nek... 96.3 1e-18
sp|A0A2R6XIK6|PRAF_MARPO RAF-like serine/threonine-protein kinase... 96.3 1e-18
sp|Q9H2K8|TAOK3_HUMAN Serine/threonine-protein kinase TAO3 OS=Hom... 95.9 1e-18
sp|Q54H46|DRKA_DICDI Probable serine/threonine-protein kinase drk... 95.1 1e-18
sp|Q9FE20|PBS1_ARATH Serine/threonine-protein kinase PBS1 OS=Arab... 94.0 1e-18
sp|Q1PDV6|PBL27_ARATH Serine/threonine-protein kinase PBL27 OS=Ar... 94.4 1e-18
sp|Q9JI11|STK4_MOUSE Serine/threonine-protein kinase 4 OS=Mus mus... 94.4 1e-18
sp|Q9P0L2|MARK1_HUMAN Serine/threonine-protein kinase MARK1 OS=Ho... 95.5 1e-18
sp|P38692|KIC1_YEAST Serine/threonine-protein kinase KIC1 OS=Sacc... 95.9 1e-18
sp|A8X775|DLK1_CAEBR Mitogen-activated protein kinase kinase kina... 95.5 1e-18
sp|Q13043|STK4_HUMAN Serine/threonine-protein kinase 4 OS=Homo sa... 94.4 1e-18
sp|Q96S53|TESK2_HUMAN Dual specificity testis-specific protein ki... 94.7 1e-18
sp|A4K2T0|STK4_MACMU Serine/threonine-protein kinase 4 OS=Macaca ... 94.4 1e-18
sp|A4K2Y1|STK4_CHLAE Serine/threonine-protein kinase 4 OS=Chloroc... 94.0 1e-18
sp|P53669|LIMK1_RAT LIM domain kinase 1 OS=Rattus norvegicus OX=1... 95.1 1e-18
sp|Q80YE4|LMTK1_MOUSE Serine/threonine-protein kinase LMTK1 OS=Mu... 95.9 1e-18
sp|Q01389|BCK1_YEAST Serine/threonine-protein kinase BCK1/SLK1/SS... 95.9 1e-18
sp|P0DP15|SNF1_FUSVI Sucrose non-fermenting protein kinase 1 OS=F... 95.1 1e-18
sp|Q54IP4|SHKB_DICDI Dual specificity protein kinase shkB OS=Dict... 95.1 1e-18
sp|Q55CE0|MKCF_DICDI Probable serine/threonine-protein kinase mkc... 95.1 1e-18
sp|A4K2Q5|STK4_OTOGA Serine/threonine-protein kinase 4 OS=Otolemu... 94.0 2e-18
sp|Q5E9L6|STK4_BOVIN Serine/threonine-protein kinase 4 OS=Bos tau... 94.0 2e-18
sp|A4K2S1|STK4_LEMCA Serine/threonine-protein kinase 4 OS=Lemur c... 94.0 2e-18
sp|Q96L34|MARK4_HUMAN MAP/microtubule affinity-regulating kinase ... 95.1 2e-18
sp|Q9FIL7|CRCK1_ARATH Calmodulin-binding receptor-like cytoplasmi... 93.6 2e-18
sp|Q9V3Q6|M3K7_DROME Mitogen-activated protein kinase kinase kina... 95.1 2e-18
sp|D3ZGQ5|NEK8_RAT Serine/threonine-protein kinase Nek8 OS=Rattus... 95.1 2e-18
sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens OX=9606... 94.7 2e-18
sp|Q8CIP4|MARK4_MOUSE MAP/microtubule affinity-regulating kinase ... 95.1 2e-18
sp|Q86SG6|NEK8_HUMAN Serine/threonine-protein kinase Nek8 OS=Homo... 94.7 2e-18
sp|Q5E9Y0|CDK2_BOVIN Cyclin-dependent kinase 2 OS=Bos taurus OX=9... 90.9 2e-18
sp|A4K2P5|STK4_COLGU Serine/threonine-protein kinase 4 OS=Colobus... 94.0 2e-18
sp|P46573|PBL10_ARATH Probable serine/threonine-protein kinase PB... 92.8 2e-18
sp|Q9FX43|M2K9_ARATH Mitogen-activated protein kinase kinase 9 OS... 91.3 2e-18
sp|Q54QQ1|PHG2_DICDI Serine/threonine-protein kinase phg2 OS=Dict... 95.5 2e-18
sp|Q7SY52|STK10_DANRE Serine/threonine-protein kinase 10 OS=Danio... 95.1 2e-18
sp|P46549|SULU_CAEEL Serine/threonine-protein kinase SULU OS=Caen... 95.1 2e-18
sp|P0C5E2|LRL12_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 94.4 2e-18
sp|Q9SAJ2|RAF20_ARATH RAF-like serine/threonine-protein kinase 20... 95.1 2e-18
sp|Q6ZMQ8|LMTK1_HUMAN Serine/threonine-protein kinase LMTK1 OS=Ho... 95.1 2e-18
sp|Q9SIT1|TMK3_ARATH Receptor-like kinase TMK3 OS=Arabidopsis tha... 95.1 2e-18
sp|O08679|MARK2_RAT Serine/threonine-protein kinase MARK2 OS=Ratt... 94.4 3e-18
sp|Q9LK43|TMK4_ARATH Receptor-like kinase TMK4 OS=Arabidopsis tha... 94.7 3e-18
sp|O64768|RAF24_ARATH RAF-like serine/threonine-protein kinase 24... 95.1 3e-18
sp|Q54WS5|ROCO6_DICDI Probable serine/threonine-protein kinase ro... 95.1 3e-18
sp|Q9V422|RYK2_DROME Tyrosine-protein kinase Dnt OS=Drosophila me... 94.0 3e-18
sp|Q32MK0|MYLK3_HUMAN Myosin light chain kinase 3 OS=Homo sapiens... 94.4 3e-18
sp|Q6Z8C8|CDKF4_ORYSJ Cyclin-dependent kinase F-4 OS=Oryza sativa... 92.8 3e-18
sp|Q7L7X3|TAOK1_HUMAN Serine/threonine-protein kinase TAO1 OS=Hom... 94.7 3e-18
sp|Q00526|CDK3_HUMAN Cyclin-dependent kinase 3 OS=Homo sapiens OX... 90.5 3e-18
sp|Q8BYC6|TAOK3_MOUSE Serine/threonine-protein kinase TAO3 OS=Mus... 94.7 3e-18
sp|Q802A6|STK4_SQUAC Serine/threonine-protein kinase 3/4 OS=Squal... 93.2 3e-18
sp|Q91ZR4|NEK8_MOUSE Serine/threonine-protein kinase Nek8 OS=Mus ... 94.0 3e-18
sp|B7ZR30|STK10_XENLA Serine/threonine-protein kinase 10-A OS=Xen... 94.4 3e-18
sp|P24941|CDK2_HUMAN Cyclin-dependent kinase 2 OS=Homo sapiens OX... 90.1 3e-18
sp|Q03141|MARK3_MOUSE MAP/microtubule affinity-regulating kinase ... 94.4 3e-18
sp|Q95KV0|IKKB_BOVIN Inhibitor of nuclear factor kappa-B kinase s... 94.4 3e-18
sp|Q9HFW2|CLA4_EREGS Serine/threonine-protein kinase CLA4 OS=Erem... 94.4 3e-18
sp|O88664|TAOK1_RAT Serine/threonine-protein kinase TAO1 OS=Rattu... 94.4 3e-18
sp|Q38997|KIN10_ARATH SNF1-related protein kinase catalytic subun... 93.2 3e-18
sp|Q5F2E8|TAOK1_MOUSE Serine/threonine-protein kinase TAO1 OS=Mus... 94.4 3e-18
sp|Q5RDG7|MYLK3_PONAB Myosin light chain kinase 3 OS=Pongo abelii... 94.4 3e-18
sp|Q9FLJ8|Y5613_ARATH Probable receptor-like protein kinase At5g6... 94.4 3e-18
sp|Q94CG0|CIPKL_ARATH CBL-interacting serine/threonine-protein ki... 92.0 4e-18
sp|O88351|IKKB_MOUSE Inhibitor of nuclear factor kappa-B kinase s... 94.0 4e-18
sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Ho... 94.0 4e-18
sp|Q6NKZ9|Y4345_ARATH Probable receptor-like serine/threonine-pro... 92.4 4e-18
sp|P0C0K7|EPHB6_RAT Ephrin type-B receptor 6 OS=Rattus norvegicus... 94.4 4e-18
sp|Q3E8W4|ANX2_ARATH Receptor-like protein kinase ANXUR2 OS=Arabi... 94.0 4e-18
sp|Q1PE89|PBL24_ARATH Probable serine/threonine-protein kinase PB... 91.7 4e-18
sp|B4KPU0|PTK7_DROMO Tyrosine-protein kinase-like otk OS=Drosophi... 94.4 4e-18
sp|Q05609|CTR1_ARATH Serine/threonine-protein kinase CTR1 OS=Arab... 94.0 4e-18
sp|C0LGE0|Y1765_ARATH Probable LRR receptor-like serine/threonine... 94.4 4e-18
sp|Q9LW83|CE101_ARATH G-type lectin S-receptor-like serine/threon... 94.0 4e-18
sp|Q852Q2|OSK1_ORYSJ Serine/threonine protein kinase OSK1 OS=Oryz... 92.8 4e-18
sp|Q94C95|ATG1A_ARATH Serine/threonine-protein kinase ATG1a OS=Ar... 93.2 5e-18
sp|Q53UA7|TAOK3_RAT Serine/threonine-protein kinase TAO3 OS=Rattu... 94.0 5e-18
sp|O42565|LIMK1_XENLA LIM domain kinase 1 OS=Xenopus laevis OX=83... 93.2 5e-18
sp|Q9NGW9|MKCB_DICDI Probable serine/threonine-protein kinase mkc... 93.6 5e-18
sp|Q04759|KPCT_HUMAN Protein kinase C theta type OS=Homo sapiens ... 93.6 5e-18
sp|A8C984|MYLK3_DANRE Myosin light chain kinase 3 OS=Danio rerio ... 93.6 5e-18
sp|Q8VHF0|MARK3_RAT MAP/microtubule affinity-regulating kinase 3 ... 93.6 5e-18
sp|Q9ZUE0|PEK12_ARATH Proline-rich receptor-like protein kinase P... 93.6 5e-18
sp|O81906|B120_ARATH G-type lectin S-receptor-like serine/threoni... 93.6 5e-18
sp|P92958|KIN11_ARATH SNF1-related protein kinase catalytic subun... 92.4 5e-18
sp|Q9FID9|Y5389_ARATH Probable receptor-like protein kinase At5g3... 93.6 6e-18
sp|Q05512|MARK2_MOUSE Serine/threonine-protein kinase MARK2 OS=Mu... 93.6 6e-18
sp|B3MH43|PTK7_DROAN Tyrosine-protein kinase-like otk OS=Drosophi... 94.0 6e-18
sp|O49545|BAME1_ARATH Leucine-rich repeat receptor-like serine/th... 93.6 6e-18
sp|Q6J9G0|STYK1_HUMAN Tyrosine-protein kinase STYK1 OS=Homo sapie... 91.3 6e-18
sp|E9PT87|MYLK3_RAT Myosin light chain kinase 3 OS=Rattus norvegi... 93.2 6e-18
sp|Q93YN1|CRPK1_ARATH Cold-responsive protein kinase 1 OS=Arabido... 90.9 7e-18
sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase ... 93.2 7e-18
sp|O14920|IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase s... 93.2 7e-18
sp|Q9FLZ3|KIN12_ARATH SNF1-related protein kinase catalytic subun... 92.0 7e-18
sp|Q9LV48|PERK1_ARATH Proline-rich receptor-like protein kinase P... 92.8 7e-18
sp|O74456|PEF1_SCHPO Serine/threonine-protein kinase pef1 OS=Schi... 89.0 7e-18
sp|Q54XJ4|Y8901_DICDI Probable serine/threonine-protein kinase DD... 93.6 8e-18
sp|O55076|CDK2_CRIGR Cyclin-dependent kinase 2 OS=Cricetulus gris... 89.0 8e-18
sp|Q6P3Q4|STK4_XENTR Serine/threonine-protein kinase 4 OS=Xenopus... 91.7 8e-18
sp|Q8MVR1|GBPC_DICDI Cyclic GMP-binding protein C OS=Dictyosteliu... 93.6 8e-18
sp|Q3UIZ8|MYLK3_MOUSE Myosin light chain kinase 3 OS=Mus musculus... 92.8 8e-18
sp|A8XJW8|CST1_CAEBR Serine/threonine-protein kinase cst-1 OS=Cae... 91.7 8e-18
sp|P50527|STE20_SCHPO Serine/threonine-protein kinase shk1/pak1 O... 92.4 9e-18
sp|P14056|ARAF_RAT Serine/threonine-protein kinase A-Raf OS=Rattu... 92.4 9e-18
sp|O08678|MARK1_RAT Serine/threonine-protein kinase MARK1 OS=Ratt... 92.8 9e-18
sp|O01700|DLK1_CAEEL Mitogen-activated protein kinase kinase kina... 93.2 9e-18
sp|Q54JQ1|MKCC_DICDI Probable serine/threonine-protein kinase mkc... 93.2 9e-18
sp|Q8VHJ5|MARK1_MOUSE Serine/threonine-protein kinase MARK1 OS=Mu... 92.8 9e-18
sp|P04627|ARAF_MOUSE Serine/threonine-protein kinase A-Raf OS=Mus... 92.4 9e-18
sp|Q6PA14|STK4_XENLA Serine/threonine-protein kinase 4 OS=Xenopus... 91.7 9e-18
sp|Q9LT96|Y5977_ARATH Probable leucine-rich repeat receptor-like ... 93.2 9e-18
sp|Q9ASQ6|Y1972_ARATH Probable LRR receptor-like serine/threonine... 93.2 1e-17
sp|Q9LX66|HERK_ARATH Receptor-like protein kinase HERK 1 OS=Arabi... 92.8 1e-17
sp|P43450|CDK2_CARAU Cyclin-dependent kinase 2 OS=Carassius aurat... 89.0 1e-17
sp|P51954|NEK1_MOUSE Serine/threonine-protein kinase Nek1 OS=Mus ... 93.2 1e-17
sp|B4HNW4|PTK7_DROSE Tyrosine-protein kinase-like otk OS=Drosophi... 92.8 1e-17
sp|O70146|TESK1_MOUSE Dual specificity testis-specific protein ki... 92.0 1e-17
sp|Q9QY78|IKKB_RAT Inhibitor of nuclear factor kappa-B kinase sub... 92.4 1e-17
sp|Q60855|RIPK1_MOUSE Receptor-interacting serine/threonine-prote... 92.0 1e-17
sp|Q9NB31|CST1_CAEEL Serine/threonine-protein kinase cst-1 OS=Cae... 91.3 1e-17
sp|Q63572|TESK1_RAT Dual specificity testis-specific protein kina... 92.0 1e-17
sp|Q2QAV0|TIO_ARATH Serine/threonine-protein kinase TIO OS=Arabid... 92.8 1e-17
sp|P17157|PHO85_YEAST Cyclin-dependent protein kinase PHO85 OS=Sa... 88.6 1e-17
sp|Q69ZA1|CDK13_MOUSE Cyclin-dependent kinase 13 OS=Mus musculus ... 92.8 1e-17
sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo ... 92.4 1e-17
sp|E1BB52|CDK13_BOVIN Cyclin-dependent kinase 13 OS=Bos taurus OX... 92.8 1e-17
sp|Q9FN92|Y5597_ARATH Probable receptor-like protein kinase At5g5... 92.4 1e-17
sp|Q14004|CDK13_HUMAN Cyclin-dependent kinase 13 OS=Homo sapiens ... 92.8 1e-17
sp|Q6AWJ9|PTK7_DROME Tyrosine-protein kinase-like otk OS=Drosophi... 92.4 1e-17
sp|Q6J9G1|STYK1_MOUSE Tyrosine-protein kinase STYK1 OS=Mus muscul... 90.5 1e-17
sp|O65530|PEK14_ARATH Proline-rich receptor-like protein kinase P... 92.0 1e-17
sp|B4QC63|PTK7_DROSI Tyrosine-protein kinase-like otk OS=Drosophi... 92.4 1e-17
sp|Q9FID8|Y5900_ARATH Putative receptor-like protein kinase At5g3... 92.4 2e-17
sp|Q0KHQ5|TAO_DROME Serine/threonine-protein kinase Tao OS=Drosop... 92.4 2e-17
sp|P48963|CDK2_MESAU Cyclin-dependent kinase 2 OS=Mesocricetus au... 88.2 2e-17
sp|O19004|ARAF_PIG Serine/threonine-protein kinase A-Raf OS=Sus s... 91.7 2e-17
sp|Q9C660|PEK10_ARATH Proline-rich receptor-like protein kinase P... 92.0 2e-17
sp|Q5ZJK4|STK4_CHICK Serine/threonine-protein kinase 4 OS=Gallus ... 90.9 2e-17
sp|Q8QFP8|LIMK1_CHICK LIM domain kinase 1 OS=Gallus gallus OX=903... 91.7 2e-17
sp|P52304|POLO_DROME Serine/threonine-protein kinase polo OS=Dros... 91.3 2e-17
sp|Q8BTW9|PAK4_MOUSE Serine/threonine-protein kinase PAK 4 OS=Mus... 91.3 2e-17
sp|P51956|NEK3_HUMAN Serine/threonine-protein kinase Nek3 OS=Homo... 90.9 2e-17
sp|Q63699|CDK2_RAT Cyclin-dependent kinase 2 OS=Rattus norvegicus... 88.2 2e-17
sp|B4P5Q9|PTK7_DROYA Tyrosine-protein kinase-like otk OS=Drosophi... 92.0 2e-17
sp|Q54RV3|PAKG_DICDI Serine/threonine-protein kinase pakG OS=Dict... 92.0 2e-17
sp|Q86YV6|MYLK4_HUMAN Myosin light chain kinase family member 4 O... 89.4 2e-17
sp|Q2RA93|WNK6_ORYSJ Probable serine/threonine-protein kinase WNK... 90.1 2e-17
sp|Q8IVT5|KSR1_HUMAN Kinase suppressor of Ras 1 OS=Homo sapiens O... 92.0 2e-17
sp|Q6FKD4|PHO85_CANGA Negative regulator of the PHO system OS=Can... 87.8 2e-17
sp|Q61G93|ROL3_CAEBR Protein roller-3 OS=Caenorhabditis briggsae ... 92.4 2e-17
sp|Q9VXE5|PAKM_DROME Serine/threonine-protein kinase PAK mbt OS=D... 91.3 2e-17
sp|Q1ZXD6|ROCO5_DICDI Probable serine/threonine-protein kinase ro... 92.4 2e-17
sp|Q9N2L7|PLK2_CAEEL Serine/threonine-protein kinase plk-2 OS=Cae... 91.3 2e-17
sp|Q41328|PTI1_SOLLC Pto-interacting protein 1 OS=Solanum lycoper... 88.6 2e-17
sp|Q86IX1|DST1_DICDI Serine/threonine-protein kinase dst1 OS=Dict... 91.3 2e-17
sp|Q9LS95|PERK6_ARATH Putative proline-rich receptor-like protein... 91.3 2e-17
sp|Q9SGY7|PEK11_ARATH Putative proline-rich receptor-like protein... 91.3 2e-17
sp|Q55D99|PAKA_DICDI Serine/threonine-protein kinase pakA OS=Dict... 91.7 3e-17
sp|P06782|SNF1_YEAST Carbon catabolite-derepressing protein kinas... 90.9 3e-17
sp|O94168|SNF1_CANTR Carbon catabolite-derepressing protein kinas... 90.9 3e-17
sp|B5DE93|CDK12_XENTR Cyclin-dependent kinase 12 OS=Xenopus tropi... 91.7 3e-17
sp|Q9LSL5|LRK92_ARATH L-type lectin-domain containing receptor ki... 91.3 3e-17
sp|Q9GN62|PAR4_CAEEL Serine/threonine-protein kinase par-4 OS=Cae... 90.9 3e-17
sp|E1BK52|STK10_BOVIN Serine/threonine-protein kinase 10 OS=Bos t... 91.7 3e-17
sp|Q28DZ1|IKKA_XENTR Inhibitor of nuclear factor kappa-B kinase s... 91.3 3e-17
sp|Q9CAH1|Y1725_ARATH Putative receptor-like protein kinase At1g7... 89.7 3e-17
sp|Q02111|KPCT_MOUSE Protein kinase C theta type OS=Mus musculus ... 90.9 3e-17
sp|B3NS99|PTK7_DROER Tyrosine-protein kinase-like otk OS=Drosophi... 91.3 3e-17
sp|Q9M2S4|LRKS4_ARATH L-type lectin-domain containing receptor ki... 90.9 3e-17
sp|Q9H4B4|PLK3_HUMAN Serine/threonine-protein kinase PLK3 OS=Homo... 90.5 3e-17
sp|Q54TH6|Y9863_DICDI Probable serine/threonine-protein kinase DD... 90.5 3e-17
sp|Q00372|SNF1_CANGA Carbon catabolite-derepressing protein kinas... 90.5 4e-17
sp|Q556S2|PAKH_DICDI Serine/threonine-protein kinase pakH OS=Dict... 90.1 4e-17
sp|Q869N2|PAKB_DICDI Serine/threonine-protein kinase pakB OS=Dict... 90.9 4e-17
sp|Q92918|M4K1_HUMAN Mitogen-activated protein kinase kinase kina... 90.9 4e-17
sp|Q9SR05|ANX1_ARATH Receptor-like protein kinase ANXUR1 OS=Arabi... 90.9 4e-17
sp|Q1PEM5|PERK3_ARATH Proline-rich receptor-like protein kinase P... 89.7 4e-17
sp|Q9ZT07|RKS1_ARATH G-type lectin S-receptor-like serine/threoni... 90.9 4e-17
sp|P53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 OS=Homo... 90.1 4e-17
sp|Q54U31|SHKD_DICDI Dual specificity protein kinase shkD OS=Dict... 90.5 4e-17
sp|Q9VI13|PAK_DROME Serine/threonine-protein kinase Pak OS=Drosop... 90.5 4e-17
sp|Q9SFX0|PBL22_ARATH Probable serine/threonine-protein kinase PB... 88.2 5e-17
sp|Q96PY6|NEK1_HUMAN Serine/threonine-protein kinase Nek1 OS=Homo... 90.9 5e-17
sp|P97377|CDK2_MOUSE Cyclin-dependent kinase 2 OS=Mus musculus OX... 87.8 5e-17
sp|B4GBH0|PTK7_DROPE Tyrosine-protein kinase-like otk OS=Drosophi... 90.9 5e-17
sp|F4JZW1|PBL13_ARATH Serine/threonine-protein kinase PBL13 OS=Ar... 89.4 5e-17
sp|G5EFU0|PK2_CAEEL Serine/threonine-protein kinase pak-2 OS=Caen... 89.4 5e-17
sp|Q9M2Z1|BAME2_ARATH Leucine-rich repeat receptor-like serine/th... 90.5 5e-17
sp|O14299|WIS4_SCHPO MAP kinase kinase kinase wis4 OS=Schizosacch... 90.9 5e-17
sp|Q7ZZC8|NEK9_XENLA Serine/threonine-protein kinase Nek9 OS=Xeno... 90.5 5e-17
sp|E9PTG8|STK10_RAT Serine/threonine-protein kinase 10 OS=Rattus ... 90.5 6e-17
sp|Q9FN94|RLK0_ARATH Receptor-like protein kinase At5g59670 OS=Ar... 90.5 6e-17
sp|O55098|STK10_MOUSE Serine/threonine-protein kinase 10 OS=Mus m... 90.5 6e-17
sp|Q290N5|PTK7_DROPS Tyrosine-protein kinase-like otk OS=Drosophi... 90.5 6e-17
sp|Q1RMT8|IRAK4_BOVIN Interleukin-1 receptor-associated kinase 4 ... 89.0 6e-17
sp|Q14AX6|CDK12_MOUSE Cyclin-dependent kinase 12 OS=Mus musculus ... 90.9 6e-17
sp|Q9T020|Y4391_ARATH Probable receptor-like protein kinase At4g3... 90.5 6e-17
sp|Q61097|KSR1_MOUSE Kinase suppressor of Ras 1 OS=Mus musculus O... 90.1 6e-17
sp|Q15569|TESK1_HUMAN Dual specificity testis-specific protein ki... 89.7 6e-17
sp|Q9M8S2|LIPG2_ARATH Receptor-like kinase LIP2 OS=Arabidopsis th... 89.4 7e-17
sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Hom... 89.4 7e-17
sp|Q9WTQ0|KPCT_RAT Protein kinase C theta type OS=Rattus norvegic... 89.7 7e-17
sp|A8WZ92|SPE8_CAEBR Spermatocyte protein spe-8 OS=Caenorhabditis... 89.0 7e-17
sp|Q3MJK5|CDK12_RAT Cyclin-dependent kinase 12 OS=Rattus norvegic... 90.5 7e-17
sp|Q552C1|Y9957_DICDI Probable serine/threonine-protein kinase DD... 90.5 7e-17
sp|Q6CWQ4|IPL1_KLULA Spindle assembly checkpoint kinase OS=Kluyve... 87.4 7e-17
sp|P10398|ARAF_HUMAN Serine/threonine-protein kinase A-Raf OS=Hom... 89.4 7e-17
sp|O22833|LRK54_ARATH L-type lectin-domain containing receptor ki... 89.7 7e-17
sp|Q9R012|PLK2_RAT Serine/threonine-protein kinase PLK2 OS=Rattus... 89.7 8e-17
sp|B5X564|CDC2C_ARATH Cyclin-dependent kinase C-2 C OS=Arabidopsi... 89.4 8e-17
sp|Q9FFW5|PERK8_ARATH Proline-rich receptor-like protein kinase P... 89.4 8e-17
sp|P53351|PLK2_MOUSE Serine/threonine-protein kinase PLK2 OS=Mus ... 89.4 9e-17
sp|Q2TA25|PLK1_BOVIN Serine/threonine-protein kinase PLK1 OS=Bos ... 89.4 9e-17
sp|Q9HGY5|PHO85_CANAX Negative regulator of the PHO system OS=Can... 86.3 1e-16
sp|Q9NYV4|CDK12_HUMAN Cyclin-dependent kinase 12 OS=Homo sapiens ... 90.1 1e-16
sp|Q5R4L1|PLK2_PONAB Serine/threonine-protein kinase PLK2 OS=Pong... 89.4 1e-16
sp|Q8RWC9|CIPK1_ARATH CBL-interacting serine/threonine-protein ki... 87.8 1e-16
sp|Q9Z1J2|NEK4_MOUSE Serine/threonine-protein kinase Nek4 OS=Mus ... 89.4 1e-16
sp|Q5QNM6|CIPKD_ORYSJ Putative CBL-interacting protein kinase 13 ... 88.6 1e-16
sp|Q9M0X5|CRK25_ARATH Cysteine-rich receptor-like protein kinase ... 89.4 1e-16
sp|Q86AE1|Y9853_DICDI Probable serine/threonine-protein kinase DD... 88.6 1e-16
sp|Q54L00|LIMKA_DICDI Probable LIM domain-containing serine/threo... 89.0 1e-16
sp|Q9NYY3|PLK2_HUMAN Serine/threonine-protein kinase PLK2 OS=Homo... 89.0 1e-16
sp|Q86HN7|PLK_DICDI Probable serine/threonine-protein kinase PLK ... 89.4 1e-16
sp|D2H526|CDK12_AILME Cyclin-dependent kinase 12 OS=Ailuropoda me... 89.7 1e-16
sp|Q9SJT0|Y2214_ARATH Probable receptor-like protein kinase At2g2... 89.4 1e-16
sp|O64793|Y1675_ARATH G-type lectin S-receptor-like serine/threon... 89.4 1e-16
sp|Q5ZJB4|IKKA_CHICK Inhibitor of nuclear factor kappa-B kinase s... 89.0 1e-16
sp|Q2ULU3|STE20_ASPOR Serine/threonine-protein kinase ste20 OS=As... 89.0 1e-16
sp|Q8GZ99|HPCA1_ARATH Leucine-rich repeat receptor protein kinase... 89.0 1e-16
sp|E1BB50|CDK12_BOVIN Cyclin-dependent kinase 12 OS=Bos taurus OX... 89.4 1e-16
sp|Q6BRY2|PHO85_DEBHA Negative regulator of the PHO system OS=Deb... 85.9 2e-16
sp|Q05006|CDC22_MEDSA Cell division control protein 2 homolog 2 O... 85.1 2e-16
sp|P34331|PLK1_CAEEL Serine/threonine-protein kinase plk-1 OS=Cae... 88.6 2e-16
sp|Q9R0A5|NEK3_MOUSE Serine/threonine-protein kinase Nek3 OS=Mus ... 87.8 2e-16
sp|O54748|STK3_RAT Serine/threonine-protein kinase 3 OS=Rattus no... 87.8 2e-16
sp|Q4G3H4|IKKA_DANRE Inhibitor of nuclear factor kappa-B kinase s... 88.6 2e-16
sp|Q6GM53|IKKA_XENLA Inhibitor of nuclear factor kappa-B kinase s... 88.6 2e-16
sp|Q54QI2|Y9877_DICDI Serine/threonine-protein kinase DDB_G028382... 89.0 2e-16
sp|Q9STK6|WNK3_ARATH Probable serine/threonine-protein kinase WNK... 87.8 2e-16
sp|Q852Q1|OSK4_ORYSJ Serine/threonine protein kinase OSK4 OS=Oryz... 87.8 2e-16
sp|B8BBT7|OSK4_ORYSI Serine/threonine protein kinase OSK4 OS=Oryz... 87.8 2e-16
sp|Q76P07|Y7165_DICDI Probable serine/threonine-protein kinase DD... 88.6 2e-16
sp|Q9SX31|PERK9_ARATH Proline-rich receptor-like protein kinase P... 88.6 2e-16
sp|Q07292|KRAF1_CAEEL Raf homolog serine/threonine-protein kinase... 88.6 2e-16
sp|Q9GRT1|MKK4_LEIME Putative mitogen-activated protein kinase ki... 85.9 2e-16
sp|Q9LQQ8|PBL5_ARATH Probable serine/threonine-protein kinase PBL... 87.0 2e-16
sp|Q9LK03|PERK2_ARATH Proline-rich receptor-like protein kinase P... 88.6 2e-16
sp|Q852Q0|OSK3_ORYSJ Serine/threonine protein kinase OSK3 OS=Oryz... 87.8 2e-16
sp|A2XFF4|OSK3_ORYSI Serine/threonine protein kinase OSK3 OS=Oryz... 87.8 2e-16
sp|Q62673|PLK1_RAT Serine/threonine-protein kinase PLK1 OS=Rattus... 88.2 2e-16
sp|Q8VZJ9|CRCK2_ARATH Calmodulin-binding receptor-like cytoplasmi... 86.7 2e-16
sp|Q9C821|PEK15_ARATH Proline-rich receptor-like protein kinase P... 87.8 2e-16
sp|Q9JI10|STK3_MOUSE Serine/threonine-protein kinase 3 OS=Mus mus... 87.4 2e-16
sp|P51957|NEK4_HUMAN Serine/threonine-protein kinase Nek4 OS=Homo... 88.6 2e-16
sp|Q5R7G9|NUAK2_PONAB NUAK family SNF1-like kinase 2 OS=Pongo abe... 88.2 2e-16
sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo sapi... 88.2 2e-16
sp|F4JBP3|ATG1B_ARATH Serine/threonine-protein kinase ATG1b OS=Ar... 88.2 2e-16
sp|O22808|LYK5_ARATH Protein LYK5 OS=Arabidopsis thaliana OX=3702... 88.2 2e-16
sp|Q9SZD5|LRK59_ARATH L-type lectin-domain containing receptor ki... 88.2 2e-16
sp|Q54MY9|MKCA_DICDI Probable serine/threonine-protein kinase mkc... 88.6 2e-16
sp|Q6IP06|STK3_XENLA Serine/threonine-protein kinase 3 OS=Xenopus... 87.4 2e-16
sp|Q9SCZ4|FERON_ARATH Receptor-like protein kinase FERONIA OS=Ara... 88.2 2e-16
sp|Q55GV3|PAKC_DICDI Serine/threonine-protein kinase pakC OS=Dict... 87.0 2e-16
sp|Q8H1G6|PTI11_ARATH PTI1-like tyrosine-protein kinase 1 OS=Arab... 85.9 2e-16
sp|Q60806|PLK3_MOUSE Serine/threonine-protein kinase PLK3 OS=Mus ... 87.8 3e-16
sp|O49339|PTI12_ARATH PTI1-like tyrosine-protein kinase 2 OS=Arab... 85.9 3e-16
sp|Q751E8|PHO85_EREGS Negative regulator of the PHO system OS=Ere... 84.7 3e-16
sp|Q9FM85|PBL16_ARATH Probable serine/threonine-protein kinase PB... 86.3 3e-16
sp|Q5AG71|HSL1_CANAL Serine/threonine-protein kinase HSL1 OS=Cand... 88.6 3e-16
sp|Q07832|PLK1_MOUSE Serine/threonine-protein kinase PLK1 OS=Mus ... 87.4 3e-16
sp|P51958|CDK1_CARAU Cyclin-dependent kinase 1 OS=Carassius aurat... 84.7 3e-16
sp|Q9M9E0|LRKS1_ARATH L-type lectin-domain containing receptor ki... 87.8 3e-16
sp|Q7ZUQ3|STK3_DANRE Serine/threonine-protein kinase 3 OS=Danio r... 87.0 3e-16
sp|C0LGW2|PAM74_ARATH Probable LRR receptor-like serine/threonine... 88.2 3e-16
sp|Q54EY4|DST3_DICDI Serine/threonine-protein kinase dst3 OS=Dict... 87.0 3e-16
sp|Q9LFT8|CDKC1_ARATH Cyclin-dependent kinase C-1 OS=Arabidopsis ... 87.0 3e-16
sp|U4PR86|MELK_CAEEL Maternal embryonic leucine zipper kinase OS=... 87.4 3e-16
sp|C0LGL4|Y2289_ARATH Probable LRR receptor-like serine/threonine... 87.8 3e-16
sp|Q84SN3|CDKF3_ORYSJ Cyclin-dependent kinase F-3 OS=Oryza sativa... 86.3 4e-16
sp|Q9FIZ3|GSO2_ARATH LRR receptor-like serine/threonine-protein k... 87.8 4e-16
sp|Q13188|STK3_HUMAN Serine/threonine-protein kinase 3 OS=Homo sa... 86.7 4e-16
sp|P83104|M3K7L_DROME Putative mitogen-activated protein kinase k... 85.5 4e-16
sp|Q90XC2|NEK8_DANRE Serine/threonine-protein kinase Nek8 OS=Dani... 87.4 4e-16
sp|Q1PDW3|LIPG1_ARATH Receptor-like kinase LIP1 OS=Arabidopsis th... 87.0 4e-16
sp|Q61UC4|KRAF1_CAEBR Raf homolog serine/threonine-protein kinase... 87.4 4e-16
sp|I1RNG8|ATG1_GIBZE Serine/threonine-protein kinase ATG1 OS=Gibb... 87.8 4e-16
sp|Q9LSE1|CDG1_ARATH Serine/threonine-protein kinase CDG1 OS=Arab... 85.9 4e-16
sp|Q9FYK0|TMK2_ARATH Receptor-like kinase TMK2 OS=Arabidopsis tha... 87.4 4e-16
sp|P0C8M8|CCR1_MAIZE Probable serine/threonine-protein kinase CCR... 87.0 4e-16
sp|F4IRW0|ATG1C_ARATH Serine/threonine-protein kinase ATG1c OS=Ar... 87.0 5e-16
sp|J4W0G2|ATG1_BEAB2 Serine/threonine-protein kinase ATG1 OS=Beau... 87.4 5e-16
sp|Q863I2|OXSR1_PIG Serine/threonine-protein kinase OSR1 OS=Sus s... 86.3 5e-16
sp|O81833|SD11_ARATH G-type lectin S-receptor-like serine/threoni... 87.0 5e-16
sp|Q54XL6|FRAY1_DICDI Serine/threonine-protein kinase fray1 OS=Di... 86.7 5e-16
sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo... 87.4 5e-16
sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens ... 87.0 5e-16
sp|Q0D541|WNK5_ORYSJ Probable serine/threonine-protein kinase WNK... 84.3 5e-16
sp|Q9FN93|Y5596_ARATH Probable LRR receptor-like serine/threonine... 87.0 5e-16
sp|Q1DN93|ATG1_COCIM Serine/threonine-protein kinase ATG1 OS=Cocc... 87.4 5e-16
sp|P32490|MKK1_YEAST MAP kinase kinase MKK1/SSP32 OS=Saccharomyce... 86.3 6e-16
sp|Q8W4P1|CDKC2_ARATH Cyclin-dependent kinase C-2 OS=Arabidopsis ... 85.9 6e-16
sp|Q94C40|CIPKH_ARATH CBL-interacting serine/threonine-protein ki... 85.5 6e-16
sp|Q96285|LRK55_ARATH L-type lectin-domain containing receptor ki... 86.7 7e-16
sp|Q9BYT3|STK33_HUMAN Serine/threonine-protein kinase 33 OS=Homo ... 85.9 7e-16
sp|Q8S8Y8|WNK6_ARATH Probable serine/threonine-protein kinase WNK... 86.3 7e-16
sp|Q8RXG3|M2K5_ARATH Mitogen-activated protein kinase kinase 5 OS... 84.3 7e-16
sp|Q4WJJ0|MKK2_ASPFU Mitogen-activated protein kinase kinae mkk2 ... 85.9 7e-16
sp|B0XPE4|MKK2_ASPFC Mitogen-activated protein kinase kinae mkk2 ... 85.9 7e-16
sp|C0LGN2|Y3148_ARATH Probable leucine-rich repeat receptor-like ... 87.0 7e-16
sp|Q9FG33|LRKS5_ARATH Probable L-type lectin-domain containing re... 86.3 7e-16
sp|Q54M77|ROCO8_DICDI Probable serine/threonine-protein kinase ro... 87.0 7e-16
sp|O59790|ARK1_SCHPO Serine/threonine-protein kinase ark1 OS=Schi... 84.3 7e-16
sp|Q8AYC9|CHK1_CHICK Serine/threonine-protein kinase Chk1 OS=Gall... 85.5 8e-16
sp|Q39203|SD22_ARATH G-type lectin S-receptor-like serine/threoni... 86.7 8e-16
sp|Q9CAL2|CRK3_ARATH Cysteine-rich receptor-like protein kinase 3... 86.3 8e-16
sp|P0CD62|LIMKB_DICDI Probable LIM domain-containing serine/threo... 86.7 8e-16
sp|O80397|M2K4_ARATH Mitogen-activated protein kinase kinase 4 OS... 84.3 8e-16
sp|Q8TGI1|ATG1_PICPA Serine/threonine-protein kinase ATG1 OS=Koma... 86.7 8e-16
sp|Q8H1E3|PBL17_ARATH Probable serine/threonine-protein kinase PB... 85.1 8e-16
sp|Q8L4H4|NORK_MEDTR Nodulation receptor kinase OS=Medicago trunc... 86.7 8e-16
sp|Q9R011|PLK3_RAT Serine/threonine-protein kinase PLK3 OS=Rattus... 86.3 8e-16
sp|C0LGR6|Y4291_ARATH Probable LRR receptor-like serine/threonine... 86.7 8e-16
sp|Q5R495|OXSR1_PONAB Serine/threonine-protein kinase OSR1 OS=Pon... 85.5 9e-16
sp|O95747|OXSR1_HUMAN Serine/threonine-protein kinase OSR1 OS=Hom... 85.5 9e-16
sp|C0LGU5|Y5457_ARATH Probable LRR receptor-like serine/threonine... 85.9 9e-16
sp|Q924X7|STK33_MOUSE Serine/threonine-protein kinase 33 OS=Mus m... 85.5 9e-16
sp|Q0D5R3|CRK6_ORYSJ Cysteine-rich receptor-like protein kinase 6... 86.3 9e-16
sp|Q65X23|WNK2_ORYSJ Probable serine/threonine-protein kinase WNK... 85.9 9e-16
sp|Q755C4|IPL1_EREGS Spindle assembly checkpoint kinase OS=Eremot... 84.0 9e-16
sp|Q59W62|GIN4_CANAL Serine/threonine-protein kinase GIN4 OS=Cand... 86.7 9e-16
sp|Q9SIB6|PBL6_ARATH Probable serine/threonine-protein kinase PBL... 84.7 1e-15
sp|Q9SEZ7|CIPKG_ARATH CBL-interacting serine/threonine-protein ki... 85.1 1e-15
sp|Q869W6|MYLKG_DICDI Probable myosin light chain kinase DDB_G027... 83.6 1e-15
sp|A2VDU3|M3K7_BOVIN Mitogen-activated protein kinase kinase kina... 85.5 1e-15
sp|P22216|RAD53_YEAST Serine/threonine-protein kinase RAD53 OS=Sa... 86.3 1e-15
sp|Q06309|CRK1_LEIME Cell division protein kinase 2 homolog CRK1 ... 82.8 1e-15
sp|O22834|LRK53_ARATH Probable L-type lectin-domain containing re... 85.9 1e-15
sp|Q5RFL3|M3K7_PONAB Mitogen-activated protein kinase kinase kina... 85.9 1e-15
sp|Q95ZQ4|AAPK2_CAEEL 5'-AMP-activated protein kinase catalytic s... 85.9 1e-15
sp|Q62073|M3K7_MOUSE Mitogen-activated protein kinase kinase kina... 85.5 1e-15
sp|O14098|CTK1_SCHPO CTD kinase subunit alpha OS=Schizosaccharomy... 85.5 1e-15
sp|P46551|CDK12_CAEEL Cyclin-dependent kinase 12 OS=Caenorhabditi... 85.9 1e-15
sp|P0C8E4|M3K7_RAT Mitogen-activated protein kinase kinase kinase... 85.5 1e-15
sp|Q75DK7|STE20_EREGS Serine/threonine-protein kinase STE20 OS=Er... 86.3 1e-15
sp|Q8K1R7|NEK9_MOUSE Serine/threonine-protein kinase Nek9 OS=Mus ... 86.3 1e-15
sp|O43318|M3K7_HUMAN Mitogen-activated protein kinase kinase kina... 85.5 1e-15
sp|P70218|M4K1_MOUSE Mitogen-activated protein kinase kinase kina... 85.9 1e-15
sp|P05986|KAPC_YEAST cAMP-dependent protein kinase type 3 OS=Sacc... 84.0 1e-15
sp|D4AE59|STK11_RAT Serine/threonine-protein kinase STK11 OS=Ratt... 84.3 1e-15
sp|Q8C015|PAK5_MOUSE Serine/threonine-protein kinase PAK 5 OS=Mus... 85.9 1e-15
sp|D4A280|PAK5_RAT Serine/threonine-protein kinase PAK 5 OS=Rattu... 85.9 1e-15
sp|Q9FIU5|CRLK1_ARATH Calcium/calmodulin-regulated receptor-like ... 84.7 1e-15
sp|Q9SGP2|HSL1_ARATH Receptor-like protein kinase HSL1 OS=Arabido... 86.3 1e-15
sp|Q6P3R8|NEK5_HUMAN Serine/threonine-protein kinase Nek5 OS=Homo... 85.9 1e-15
sp|C0LGQ5|GSO1_ARATH LRR receptor-like serine/threonine-protein k... 86.3 1e-15
sp|Q8VYT3|Y4052_ARATH Probable LRR receptor-like serine/threonine... 85.5 1e-15
sp|C0LGT5|Y5169_ARATH Probable LRR receptor-like serine/threonine... 85.9 1e-15
sp|Q9ZVP5|M3K18_ARATH Mitogen-activated protein kinase kinase kin... 83.2 1e-15
sp|Q0GGW5|STK11_CHICK Serine/threonine-protein kinase STK11 OS=Ga... 84.3 1e-15
sp|P70032|PLK1_XENLA Serine/threonine-protein kinase PLK1 OS=Xeno... 85.5 1e-15
sp|P93749|Y2197_ARATH Probable protein kinase At2g41970 OS=Arabid... 83.6 1e-15
sp|Q9M020|LRK63_ARATH Lectin-domain containing receptor kinase VI... 85.5 1e-15
sp|P18161|SPLB_DICDI Dual specificity protein kinase splB OS=Dict... 86.3 1e-15
sp|Q8LKZ1|NORK_PEA Nodulation receptor kinase OS=Pisum sativum OX... 85.9 1e-15
sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo... 85.5 1e-15
sp|Q9SY89|Y1661_ARATH Putative G-type lectin S-receptor-like seri... 85.9 2e-15
sp|Q9M1Z9|LRK58_ARATH Putative L-type lectin-domain containing re... 85.1 2e-15
sp|O75011|NAK1_SCHPO Serine/threonine-protein kinase nak1 OS=Schi... 85.5 2e-15
sp|O81832|Y4729_ARATH G-type lectin S-receptor-like serine/threon... 85.5 2e-15
sp|Q5Z6X0|CIPKP_ORYSJ CBL-interacting protein kinase 25 OS=Oryza ... 84.7 2e-15
sp|Q6CVA2|STE20_KLULA Serine/threonine-protein kinase STE20 OS=Kl... 85.9 2e-15
sp|Q3ULB5|PAK6_MOUSE Serine/threonine-protein kinase PAK 6 OS=Mus... 85.5 2e-15
sp|P62205|PLK1_XENTR Serine/threonine-protein kinase PLK1 OS=Xeno... 85.1 2e-15
sp|Q9P286|PAK5_HUMAN Serine/threonine-protein kinase PAK 5 OS=Hom... 85.5 2e-15
sp|C0LGG6|Y5189_ARATH Probable LRR receptor-like protein kinase A... 85.5 2e-15
sp|Q9FLW0|Y5241_ARATH Probable receptor-like protein kinase At5g2... 85.5 2e-15
sp|Q9M8J5|M2K8_ARATH Mitogen-activated protein kinase kinase 8 OS... 82.4 2e-15
sp|Q9C823|Y1523_ARATH C-type lectin receptor-like tyrosine-protei... 84.7 2e-15
sp|Q8S9L6|CRK29_ARATH Cysteine-rich receptor-like protein kinase ... 85.1 2e-15
sp|P24583|KPC1_YEAST Protein kinase C-like 1 OS=Saccharomyces cer... 85.9 2e-15
sp|Q9WTK7|STK11_MOUSE Serine/threonine-protein kinase STK11 OS=Mu... 84.0 2e-15
sp|Q9LFG1|Y3359_ARATH Putative leucine-rich repeat receptor-like ... 85.5 2e-15
sp|Q5JK68|CDKC2_ORYSJ Cyclin-dependent kinase C-2 OS=Oryza sativa... 84.7 2e-15
sp|Q0VD22|STK33_BOVIN Serine/threonine-protein kinase 33 OS=Bos t... 84.3 2e-15
sp|Q63531|KS6A1_RAT Ribosomal protein S6 kinase alpha-1 OS=Rattus... 85.1 2e-15
sp|O22187|Y2232_ARATH Probable receptor-like protein kinase At2g2... 85.5 2e-15
sp|Q9SXB5|Y1135_ARATH G-type lectin S-receptor-like serine/threon... 85.5 2e-15
sp|P43294|MHK_ARATH Serine/threonine-protein kinase MHK OS=Arabid... 84.0 2e-15
sp|Q6DE87|CHK1_XENLA Serine/threonine-protein kinase Chk1 OS=Xeno... 84.3 2e-15
sp|Q66HE5|NUAK2_RAT NUAK family SNF1-like kinase 2 OS=Rattus norv... 85.1 2e-15
sp|Q5JLD8|CIPK8_ORYSJ CBL-interacting protein kinase 8 OS=Oryza s... 84.0 2e-15
sp|Q5R8Z4|PAK6_PONAB Serine/threonine-protein kinase PAK 6 OS=Pon... 85.1 2e-15
sp|Q64303|PAK2_RAT Serine/threonine-protein kinase PAK 2 OS=Rattu... 84.3 2e-15
sp|Q9NQU5|PAK6_HUMAN Serine/threonine-protein kinase PAK 6 OS=Hom... 84.7 2e-15
sp|Q6FV07|IPL1_CANGA Spindle assembly checkpoint kinase OS=Candid... 82.8 2e-15
sp|Q6P9R2|OXSR1_MOUSE Serine/threonine-protein kinase OSR1 OS=Mus... 84.3 2e-15
sp|A0A8I5ZNK2|OXSR1_RAT Serine/threonine-protein kinase OSR1 OS=R... 84.3 2e-15
sp|Q6I5Y0|CDKC1_ORYSJ Cyclin-dependent kinase C-1 OS=Oryza sativa... 84.3 2e-15
sp|Q8GUH1|PUB33_ARATH U-box domain-containing protein 33 OS=Arabi... 85.1 2e-15
sp|C0LGG9|Y5344_ARATH Probable LRR receptor-like serine/threonine... 85.1 2e-15
sp|Q8CIN4|PAK2_MOUSE Serine/threonine-protein kinase PAK 2 OS=Mus... 84.3 2e-15
sp|Q9FX99|Y1497_ARATH Probable receptor-like protein kinase At1g4... 84.7 2e-15
sp|Q29502|PAK2_RABIT Serine/threonine-protein kinase PAK 2 OS=Ory... 84.3 2e-15
sp|Q4P5N0|STE20_USTMA Serine/threonine-protein kinase SMU1 OS=Ust... 84.7 2e-15
sp|Q7RAH3|CDPK1_PLAYO Calcium-dependent protein kinase 1 OS=Plasm... 84.3 3e-15
sp|C0LGU1|Y5374_ARATH Probable LRR receptor-like serine/threonine... 85.1 3e-15
sp|Q08E52|PAK1_BOVIN Serine/threonine-protein kinase PAK 1 OS=Bos... 84.3 3e-15
sp|Q9SXB8|Y1133_ARATH G-type lectin S-receptor-like serine/threon... 84.7 3e-15
sp|Q9LK35|THE1_ARATH Receptor-like protein kinase THESEUS 1 OS=Ar... 84.7 3e-15
sp|G5EGT9|RYK_CAEEL Inactive tyrosine-protein kinase RYK OS=Caeno... 84.3 3e-15
sp|P0CY24|STE20_CANAL Serine/threonine-protein kinase CST20 OS=Ca... 85.1 3e-15
sp|Q66GN2|LRK64_ARATH Lectin-domain containing receptor kinase VI... 84.7 3e-15
sp|O88643|PAK1_MOUSE Serine/threonine-protein kinase PAK 1 OS=Mus... 84.0 3e-15
sp|Q39030|KPK2_ARATH Serine/threonine-protein kinase AtPK2/AtPK19... 83.6 3e-15
sp|Q13153|PAK1_HUMAN Serine/threonine-protein kinase PAK 1 OS=Hom... 84.0 3e-15
sp|C4YRB7|STE20_CANAW Serine/threonine-protein kinase CST20 OS=Ca... 85.1 3e-15
sp|Q9LVP0|Y5639_ARATH Probable leucine-rich repeat receptor-like ... 85.1 3e-15
sp|Q9URY1|PPK16_SCHPO Serine/threonine-protein kinase ppk16 OS=Sc... 84.3 3e-15
sp|Q54Y90|Y0133_DICDI Probable serine/threonine-protein kinase DD... 85.1 3e-15
sp|P0CY23|STE20_CANAX Serine/threonine-protein kinase CST20 OS=Ca... 85.1 3e-15
sp|P35465|PAK1_RAT Serine/threonine-protein kinase PAK 1 OS=Rattu... 84.0 3e-15
sp|Q6C7U8|PHO85_YARLI Negative regulator of the PHO system OS=Yar... 81.3 3e-15
sp|A0A509AHB6|CDPK1_PLABA Calcium-dependent protein kinase 1 OS=P... 84.0 3e-15
sp|Q13177|PAK2_HUMAN Serine/threonine-protein kinase PAK 2 OS=Hom... 84.0 3e-15
sp|P93050|RKF3_ARATH Probable LRR receptor-like serine/threonine-... 84.3 3e-15
sp|Q8AXB4|PAK3_XENLA Serine/threonine-protein kinase PAK 3 OS=Xen... 84.0 3e-15
sp|P51839|GUC2D_RAT Guanylate cyclase 2D OS=Rattus norvegicus OX=... 85.1 3e-15
sp|Q17850|PK1_CAEEL Serine/threonine-protein kinase pak-1 OS=Caen... 84.0 3e-15
sp|C0LGH2|Y1561_ARATH Probable LRR receptor-like serine/threonine... 84.7 3e-15
sp|Q5SUV5|MYLK4_MOUSE Myosin light chain kinase family member 4 O... 82.8 3e-15
sp|Q03147|CDK7_MOUSE Cyclin-dependent kinase 7 OS=Mus musculus OX... 82.0 3e-15
sp|C0LGD9|Y1756_ARATH Probable LRR receptor-like serine/threonine... 84.3 4e-15
sp|P50613|CDK7_HUMAN Cyclin-dependent kinase 7 OS=Homo sapiens OX... 82.0 4e-15
sp|Q9LPZ3|Y1141_ARATH G-type lectin S-receptor-like serine/threon... 84.3 4e-15
sp|A8X0C4|PAR4_CAEBR Serine/threonine-protein kinase par-4 OS=Cae... 84.0 4e-15
sp|C0LGG8|Y5343_ARATH Probable LRR receptor-like serine/threonine... 84.7 4e-15
sp|Q9R0G8|NRK_MOUSE Nik-related protein kinase OS=Mus musculus OX... 84.7 4e-15
sp|Q6I5Q6|RK185_ORYSJ Receptor-like cytoplasmic kinase 185 OS=Ory... 83.2 4e-15
sp|A8R7E6|CERK1_ARATH Chitin elicitor receptor kinase 1 OS=Arabid... 84.0 4e-15
sp|Q9NWZ3|IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 ... 83.2 4e-15
sp|O80623|Y2393_ARATH Probable receptor-like protein kinase At2g3... 84.3 4e-15
sp|A9S5R3|M2K1C_PHYPA Mitogen-activated protein kinase kinase 1c ... 81.6 4e-15
sp|Q8LST2|WNK7_ARATH Probable serine/threonine-protein kinase WNK... 83.6 4e-15
sp|P47735|RLK5_ARATH Receptor-like protein kinase 5 OS=Arabidopsi... 84.3 4e-15
sp|O04086|Y1105_ARATH Probable receptor-like protein kinase At1g1... 84.0 4e-15
sp|Q08942|NRKA_TRYBB Putative serine/threonine-protein kinase A O... 82.8 4e-15
sp|Q92241|PHO85_KLULA Negative regulator of the PHO system OS=Klu... 80.9 4e-15
sp|Q9LEU7|CIPK5_ARATH CBL-interacting serine/threonine-protein ki... 82.8 4e-15
sp|Q9Z1W9|STK39_MOUSE STE20/SPS1-related proline-alanine-rich pro... 83.6 4e-15
sp|O14427|CLA4_CANAX Serine/threonine-protein kinase CLA4 OS=Cand... 84.3 4e-15
sp|Q54B33|PAKE_DICDI Serine/threonine-protein kinase pakE OS=Dict... 84.3 5e-15
sp|Q5APR8|CLA4_CANAL Serine/threonine-protein kinase CLA4 OS=Cand... 84.3 5e-15
sp|Q9UEW8|STK39_HUMAN STE20/SPS1-related proline-alanine-rich pro... 83.6 5e-15
sp|O88506|STK39_RAT STE20/SPS1-related proline-alanine-rich prote... 83.6 5e-15
sp|F4JEQ2|PBL23_ARATH Probable serine/threonine-protein kinase PB... 82.0 5e-15
sp|Q12263|GIN4_YEAST Serine/threonine-protein kinase GIN4 OS=Sacc... 84.3 5e-15
sp|A8X5H5|GSK3_CAEBR Glycogen synthase kinase-3 OS=Caenorhabditis... 81.6 5e-15
sp|Q8C078|KKCC2_MOUSE Calcium/calmodulin-dependent protein kinase... 83.6 5e-15
sp|Q15131|CDK10_HUMAN Cyclin-dependent kinase 10 OS=Homo sapiens ... 81.6 5e-15
sp|C0LGI2|Y1677_ARATH Probable LRR receptor-like serine/threonine... 84.3 5e-15
sp|O13839|FIN1_SCHPO G2-specific protein kinase fin1 OS=Schizosac... 84.0 5e-15
sp|O64778|Y1142_ARATH G-type lectin S-receptor-like serine/threon... 84.0 5e-15
sp|Q552C6|ZAK2_DICDI Dual specificity protein kinase zak2 OS=Dict... 83.6 5e-15
sp|O64477|Y2913_ARATH G-type lectin S-receptor-like serine/threon... 84.0 5e-15
sp|O23304|BLUS1_ARATH Serine/threonine-protein kinase BLUS1 OS=Ar... 82.8 5e-15
sp|Q86CS2|ATG1_DICDI Serine/threonine-protein kinase atg1 OS=Dict... 83.6 5e-15
sp|C0LGH3|Y5614_ARATH Probable LRR receptor-like serine/threonine... 84.0 5e-15
sp|Q9LUT0|CARK1_ARATH Receptor-like cytoplasmic kinase 1 OS=Arabi... 81.6 5e-15
sp|O88831|KKCC2_RAT Calcium/calmodulin-dependent protein kinase k... 83.2 5e-15
sp|O64771|Y1148_ARATH G-type lectin S-receptor-like serine/threon... 84.0 6e-15
sp|O61661|CHK1_DROME Serine/threonine-protein kinase grp OS=Droso... 82.8 6e-15
sp|Q8INB9|AKT1_DROME RAC serine/threonine-protein kinase OS=Droso... 83.6 6e-15
sp|Q621J7|ZYG1_CAEBR Probable serine/threonine-protein kinase zyg... 83.6 6e-15
sp|Q9LP51|CIPKI_ARATH CBL-interacting serine/threonine-protein ki... 83.2 6e-15
sp|Q8W1D5|CIPKP_ARATH CBL-interacting serine/threonine-protein ki... 82.8 6e-15
sp|Q8BPM2|M4K5_MOUSE Mitogen-activated protein kinase kinase kina... 84.0 6e-15
sp|Q9M342|WAKLP_ARATH Wall-associated receptor kinase-like 15 OS=... 83.6 6e-15
sp|Q9HFF4|PPK1_SCHPO Serine/threonine-protein kinase ppk1 OS=Schi... 84.0 6e-15
sp|Q01919|KIN4_YEAST Serine/threonine-protein kinase KIN4 OS=Sacc... 83.6 6e-15
sp|Q7RZD3|STE20_NEUCR Serine/threonine-protein kinase ste20 OS=Ne... 84.0 6e-15
sp|O04533|LRK52_ARATH Putative L-type lectin-domain containing re... 83.2 6e-15
sp|Q2TBL8|CDK10_BOVIN Cyclin-dependent kinase 10 OS=Bos taurus OX... 81.3 7e-15
sp|Q2VWQ3|STE20_TALMA Serine/threonine-protein kinase pakA OS=Tal... 83.2 7e-15
sp|Q8GYA4|CRK10_ARATH Cysteine-rich receptor-like protein kinase ... 83.2 7e-15
sp|Q15831|STK11_HUMAN Serine/threonine-protein kinase STK11 OS=Ho... 82.0 7e-15
sp|O88866|HUNK_MOUSE Hormonally up-regulated neu tumor-associated... 83.6 7e-15
sp|Q3UMM4|CDK10_MOUSE Cyclin-dependent kinase 10 OS=Mus musculus ... 81.3 7e-15
sp|P34722|KPC1_CAEEL Protein kinase C-like 1 OS=Caenorhabditis el... 83.2 7e-15
sp|Q9Y4K4|M4K5_HUMAN Mitogen-activated protein kinase kinase kina... 83.6 7e-15
sp|Q9U2Q9|GSK3_CAEEL Glycogen synthase kinase-3 OS=Caenorhabditis... 81.3 7e-15
sp|Q9W739|CDK1_RANDY Cyclin-dependent kinase 1 OS=Rana dybowskii ... 80.5 7e-15
sp|P48562|CLA4_YEAST Serine/threonine-protein kinase CLA4 OS=Sacc... 83.6 7e-15
sp|Q9LXA5|LRK91_ARATH L-type lectin-domain containing receptor ki... 83.2 7e-15
sp|Q55FS2|STK4L_DICDI Serine/threonine-protein kinase 4 homolog B... 83.6 8e-15
sp|Q8VCR8|MYLK2_MOUSE Myosin light chain kinase 2, skeletal/cardi... 83.2 8e-15
sp|Q55GE6|ROCO7_DICDI Probable serine/threonine-protein kinase ro... 84.0 8e-15
sp|Q8KY50|STKP_STREE Serine/threonine-protein kinase StkP OS=Stre... 83.2 8e-15
sp|Q6C3J2|IPL1_YARLI Spindle assembly checkpoint kinase OS=Yarrow... 81.3 8e-15
sp|Q9LHP4|RGI1_ARATH LRR receptor-like serine/threonine-protein k... 83.6 8e-15
sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo sapi... 83.2 8e-15
sp|Q9SXB4|Y1130_ARATH G-type lectin S-receptor-like serine/threon... 83.2 8e-15
sp|Q4WHP3|STE20_ASPFU Serine/threonine-protein kinase ste20 OS=As... 83.2 8e-15
sp|Q9SJG2|Y2296_ARATH Probable receptor-like protein kinase At2g4... 82.4 8e-15
sp|A9SR33|M2K1B_PHYPA Mitogen-activated protein kinase kinase 1b ... 80.9 8e-15
sp|Q8T0S6|HIPPO_DROME Serine/threonine-protein kinase hippo OS=Dr... 83.2 8e-15
sp|C0LGV0|Y5487_ARATH Probable LRR receptor-like serine/threonine... 83.2 8e-15
sp|P13185|KIN1_YEAST Serine/threonine protein kinase KIN1 OS=Sacc... 83.6 9e-15
sp|F1LP90|MINK1_RAT Misshapen-like kinase 1 OS=Rattus norvegicus ... 83.6 9e-15
sp|A0A2I0BVG8|CDPK1_PLAFO Calcium-dependent protein kinase 1 OS=P... 82.4 9e-15
sp|P62343|CDPK1_PLAFK Calcium-dependent protein kinase 1 OS=Plasm... 82.4 9e-15
sp|P62344|CDPK1_PLAF7 Calcium-dependent protein kinase 1 OS=Plasm... 82.4 9e-15
sp|Q7YQL3|PAK3_PONPY Serine/threonine-protein kinase PAK 3 OS=Pon... 82.8 9e-15
sp|Q7YQL4|PAK3_PANTR Serine/threonine-protein kinase PAK 3 OS=Pan... 82.8 9e-15
sp|O75914|PAK3_HUMAN Serine/threonine-protein kinase PAK 3 OS=Hom... 82.8 9e-15
sp|Q09170|CDS1_SCHPO Serine/threonine-protein kinase cds1 OS=Schi... 82.0 9e-15
sp|Q62829|PAK3_RAT Serine/threonine-protein kinase PAK 3 OS=Rattu... 82.4 9e-15
sp|Q942F3|BRI1_ORYSJ Brassinosteroid LRR receptor kinase BRI1 OS=... 83.6 9e-15
sp|O22971|CIPKD_ARATH CBL-interacting serine/threonine-protein ki... 82.4 9e-15
sp|O64781|Y1639_ARATH G-type lectin S-receptor-like serine/threon... 83.2 9e-15
sp|A4IFM7|MYLK2_BOVIN Myosin light chain kinase 2, skeletal/cardi... 82.8 9e-15
sp|Q8SRF5|Y823_ENCCU Probable cell division protein kinase ECU08_... 79.3 9e-15
sp|Q9LYN8|EMS1_ARATH Leucine-rich repeat receptor protein kinase ... 83.6 9e-15
sp|Q61036|PAK3_MOUSE Serine/threonine-protein kinase PAK 3 OS=Mus... 82.4 9e-15
sp|Q4KM47|CDK10_RAT Cyclin-dependent kinase 10 OS=Rattus norvegic... 80.9 9e-15
sp|P07313|MYLK2_RABIT Myosin light chain kinase 2, skeletal/cardi... 82.8 9e-15
sp|P34099|KAPC_DICDI cAMP-dependent protein kinase catalytic subu... 82.8 1e-14
sp|P45894|AAPK1_CAEEL 5'-AMP-activated protein kinase catalytic s... 82.4 1e-14
sp|O65479|CRK20_ARATH Putative cysteine-rich receptor-like protei... 82.8 1e-14
sp|Q8N4C8|MINK1_HUMAN Misshapen-like kinase 1 OS=Homo sapiens OX=... 83.6 1e-14
sp|Q03963|E2AK2_MOUSE Interferon-induced, double-stranded RNA-act... 82.4 1e-14
sp|Q96RR4|KKCC2_HUMAN Calcium/calmodulin-dependent protein kinase... 82.4 1e-14
sp|O08815|SLK_RAT STE20-like serine/threonine-protein kinase OS=R... 83.2 1e-14
sp|Q9JM52|MINK1_MOUSE Misshapen-like kinase 1 OS=Mus musculus OX=... 83.2 1e-14
sp|O80888|M3K17_ARATH Mitogen-activated protein kinase kinase kin... 80.9 1e-14
sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo sa... 82.0 1e-14
sp|Q9TXJ0|CMK1_CAEEL Calcium/calmodulin-dependent protein kinase ... 80.5 1e-14
sp|P24100|CDKA1_ARATH Cyclin-dependent kinase A-1 OS=Arabidopsis ... 79.7 1e-14
sp|Q9SYA0|Y1150_ARATH G-type lectin S-receptor-like serine/threon... 82.8 1e-14
sp|Q38868|CDPK9_ARATH Calcium-dependent protein kinase 9 OS=Arabi... 82.0 1e-14
sp|Q91ZN7|CHK1_RAT Serine/threonine-protein kinase Chk1 OS=Rattus... 81.6 1e-14
sp|Q8BRK8|AAPK2_MOUSE 5'-AMP-activated protein kinase catalytic s... 82.0 1e-14
sp|O54988|SLK_MOUSE STE20-like serine/threonine-protein kinase OS... 83.2 1e-14
sp|D7UPN3|RLK10_ORYSJ LysM domain receptor-like kinase 10 OS=Oryz... 82.4 1e-14
sp|Q09137|AAPK2_RAT 5'-AMP-activated protein kinase catalytic sub... 82.0 1e-14
sp|Q8RWZ5|SD25_ARATH G-type lectin S-receptor-like serine/threoni... 82.8 1e-14
sp|C0LGP2|MEE39_ARATH Probable LRR receptor-like serine/threonine... 82.8 1e-14
sp|Q8RXC8|RBK2_ARATH Receptor-like cytosolic serine/threonine-pro... 81.6 1e-14
sp|Q8S8S7|PUB34_ARATH U-box domain-containing protein 34 OS=Arabi... 82.8 1e-14
sp|P20689|MYLK2_RAT Myosin light chain kinase 2, skeletal/cardiac... 82.4 1e-14
sp|O70405|ULK1_MOUSE Serine/threonine-protein kinase ULK1 OS=Mus ... 82.8 1e-14
sp|Q54HC6|ARKA_DICDI Ankyrin repeat-containing protein kinase A O... 83.2 1e-14
sp|Q54G43|SHKE_DICDI Dual specificity protein kinase shkE OS=Dict... 82.4 1e-14
sp|Q6BVA0|IPL1_DEBHA Spindle assembly checkpoint kinase OS=Debary... 81.3 1e-14
sp|Q04735|CDK16_MOUSE Cyclin-dependent kinase 16 OS=Mus musculus ... 81.6 1e-14
sp|Q54MV2|MRKB_DICDI Probable serine/threonine-protein kinase MAR... 82.4 1e-14
sp|Q8GWJ7|CRK19_ARATH Cysteine-rich receptor-like protein kinase ... 82.4 1e-14
sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo... 81.6 1e-14
sp|O75385|ULK1_HUMAN Serine/threonine-protein kinase ULK1 OS=Homo... 82.8 1e-14
sp|Q5PU49|KPCD_CANLF Protein kinase C delta type OS=Canis lupus f... 82.4 1e-14
sp|Q60680|IKKA_MOUSE Inhibitor of nuclear factor kappa-B kinase s... 82.4 1e-14
sp|O55092|SLK_CAVPO STE20-like serine/threonine-protein kinase OS... 82.8 1e-14
sp|Q63686|CDK16_RAT Cyclin-dependent kinase 16 OS=Rattus norvegic... 81.6 1e-14
sp|P87248|ATG1_COLLN Serine/threonine-protein kinase ATG1 OS=Coll... 82.4 1e-14
sp|Q9UIK4|DAPK2_HUMAN Death-associated protein kinase 2 OS=Homo s... 80.5 1e-14
sp|Q9WUT3|KS6A2_MOUSE Ribosomal protein S6 kinase alpha-2 OS=Mus ... 82.4 2e-14
sp|Q0UY20|ATG1_PHANO Serine/threonine-protein kinase atg1 OS=Phae... 82.4 2e-14
sp|O64556|Y2923_ARATH Putative leucine-rich repeat receptor-like ... 82.4 2e-14
sp|Q97PA9|STKP_STRPN Serine/threonine-protein kinase StkP OS=Stre... 82.0 2e-14
sp|Q3ZDQ4|ATG1_PODAS Serine/threonine-protein kinase ATG1 OS=Podo... 82.4 2e-14
sp|Q8DNS0|STKP_STRR6 Serine/threonine-protein kinase StkP OS=Stre... 82.0 2e-14
sp|Q04J43|STKP_STRP2 Serine/threonine-protein kinase StkP OS=Stre... 82.0 2e-14
sp|Q7TSC3|NEK5_MOUSE Serine/threonine-protein kinase Nek5 OS=Mus ... 82.0 2e-14
sp|Q0WVM4|Y2239_ARATH Probable LRR receptor-like serine/threonine... 82.0 2e-14
sp|Q9FII5|TDR_ARATH Leucine-rich repeat receptor-like protein kin... 82.4 2e-14
sp|O22476|BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 OS=Ara... 82.4 2e-14
sp|G5ECH7|CDK5_CAEEL Cyclin-dependent-like kinase 5 OS=Caenorhabd... 79.0 2e-14
sp|Q9SHI2|Y1723_ARATH Leucine-rich repeat receptor-like serine/th... 82.4 2e-14
sp|Q28948|AAPK2_PIG 5'-AMP-activated protein kinase catalytic sub... 81.6 2e-14
sp|P54646|AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic s... 81.6 2e-14
sp|P34112|CDK1_DICDI Cyclin-dependent kinase 1 OS=Dictyostelium d... 79.0 2e-14
sp|Q4WVG0|PKCA_ASPFU Protein kinase C OS=Aspergillus fumigatus (s... 82.4 2e-14
sp|Q9ZRF9|RPK1_ARATH Probable LRR receptor-like serine/threonine-... 81.6 2e-14
sp|Q00536|CDK16_HUMAN Cyclin-dependent kinase 16 OS=Homo sapiens ... 81.3 2e-14
sp|A0A0U1RPR8|GUC2D_MOUSE Guanylate cyclase D OS=Mus musculus OX=... 82.4 2e-14
sp|Q6ZLP5|CIPKN_ORYSJ CBL-interacting protein kinase 23 OS=Oryza ... 80.9 2e-14
sp|Q5RD00|AAPK2_PONAB 5'-AMP-activated protein kinase catalytic s... 81.6 2e-14
sp|Q9C6P3|CDPKX_ARATH Calcium-dependent protein kinase 33 OS=Arab... 81.3 2e-14
sp|Q54WJ0|STK11_DICDI Serine/threonine-protein kinase stk11 homol... 81.6 2e-14
sp|P42818|KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6 ... 80.9 2e-14
sp|Q0D4B2|CIPKL_ORYSJ CBL-interacting protein kinase 21 OS=Oryza ... 81.3 2e-14
sp|Q9ZR08|Y4230_ARATH G-type lectin S-receptor-like serine/threon... 82.0 2e-14
sp|Q641K5|NUAK1_MOUSE NUAK family SNF1-like kinase 1 OS=Mus muscu... 81.6 2e-14
sp|P13186|KIN2_YEAST Serine/threonine-protein kinase KIN2 OS=Sacc... 82.4 2e-14
sp|Q8BZ25|ANKK1_MOUSE Ankyrin repeat and protein kinase domain-co... 82.0 2e-14
sp|Q9SR87|LRK61_ARATH Probable L-type lectin-domain containing re... 81.6 2e-14
sp|Q13233|M3K1_HUMAN Mitogen-activated protein kinase kinase kina... 82.4 2e-14
sp|A3B529|CIPKS_ORYSJ CBL-interacting protein kinase 28 OS=Oryza ... 80.5 2e-14
sp|Q69Q47|CIPKO_ORYSJ CBL-interacting protein kinase 24 OS=Oryza ... 80.9 2e-14
sp|Q9SYS3|CRK40_ARATH Cysteine-rich receptor-like protein kinase ... 81.6 2e-14
sp|Q39192|SRK2D_ARATH Serine/threonine-protein kinase SRK2D OS=Ar... 79.7 2e-14
sp|P25323|MYLKA_DICDI Myosin light chain kinase A OS=Dictyosteliu... 79.0 2e-14
sp|Q6UD73|LYK3_MEDTR LysM domain receptor-like kinase 3 OS=Medica... 81.6 2e-14
sp|Q9S9M2|WAKLD_ARATH Wall-associated receptor kinase-like 4 OS=A... 81.6 2e-14
sp|Q54RB2|CDK11_DICDI Cyclin-dependent kinase 11 OS=Dictyostelium... 79.7 2e-14
sp|P0DL10|TD1_MAIZE Leucine-rich repeat receptor-like kinase prot... 82.0 2e-14
sp|Q9LZU4|CRK4_ARATH Cysteine-rich receptor-like protein kinase 4... 81.6 2e-14
sp|Q9ZVR7|PSKR1_ARATH Phytosulfokine receptor 1 OS=Arabidopsis th... 82.0 2e-14
sp|P07527|WEE1_SCHPO Mitosis inhibitor protein kinase wee1 OS=Sch... 82.0 2e-14
sp|P13863|CDK1_CHICK Cyclin-dependent kinase 1 OS=Gallus gallus O... 79.0 2e-14
sp|Q9H1R3|MYLK2_HUMAN Myosin light chain kinase 2, skeletal/cardi... 81.3 2e-14
sp|Q924I2|M4K3_RAT Mitogen-activated protein kinase kinase kinase... 81.6 2e-14
sp|Q91604|STK11_XENLA Serine/threonine-protein kinase stk11 OS=Xe... 80.5 2e-14
sp|Q9LFV3|CRLK2_ARATH Calcium/calmodulin-regulated receptor-like ... 80.5 2e-14
sp|P54645|AAPK1_RAT 5'-AMP-activated protein kinase catalytic sub... 81.3 2e-14
sp|O42632|KPC1_COCHE Protein kinase C-like OS=Cochliobolus hetero... 82.0 2e-14
sp|Q38772|CDC2A_ANTMA Cell division control protein 2 homolog A O... 78.6 3e-14
sp|Q9FJ55|CIPKJ_ARATH CBL-interacting serine/threonine-protein ki... 80.9 3e-14
sp|Q5GIG6|TNI3K_MOUSE Serine/threonine-protein kinase TNNI3K OS=M... 81.6 3e-14
sp|Q9ZWC8|BRL1_ARATH Serine/threonine-protein kinase BRI1-like 1 ... 82.0 3e-14
sp|Q8VDF3|DAPK2_MOUSE Death-associated protein kinase 2 OS=Mus mu... 79.7 3e-14
sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic s... 81.3 3e-14
sp|O35280|CHK1_MOUSE Serine/threonine-protein kinase Chk1 OS=Mus ... 80.9 3e-14
sp|F4I1N8|ATG1T_ARATH Serine/threonine-protein kinase ATG1t OS=Ar... 80.1 3e-14
sp|Q5EG47|AAPK1_MOUSE 5'-AMP-activated protein kinase catalytic s... 81.3 3e-14
sp|Q5JLQ9|CIPKU_ORYSJ CBL-interacting protein kinase 30 OS=Oryza ... 80.9 3e-14
sp|P51952|CDK7_RAT Cyclin-dependent kinase 7 (Fragment) OS=Rattus... 79.0 3e-14
sp|P10665|KS6AA_XENLA Ribosomal protein S6 kinase 2 alpha OS=Xeno... 81.6 3e-14
sp|Q7TQP6|TNI3K_RAT Serine/threonine-protein kinase TNNI3K OS=Rat... 81.6 3e-14
sp|O80939|LRK41_ARATH L-type lectin-domain containing receptor ki... 81.3 3e-14
sp|Q9SNA3|Y3463_ARATH Putative receptor-like protein kinase At3g4... 81.6 3e-14
sp|O43293|DAPK3_HUMAN Death-associated protein kinase 3 OS=Homo s... 80.5 3e-14
sp|Q19469|SAD1_CAEEL Serine/threonine kinase SAD-1 OS=Caenorhabdi... 81.6 3e-14
sp|Q68UT7|HUNK_PANTR Hormonally up-regulated neu tumor-associated... 81.3 3e-14
sp|Q9Y572|RIPK3_HUMAN Receptor-interacting serine/threonine-prote... 80.9 3e-14
sp|P18265|GSK3A_RAT Glycogen synthase kinase-3 alpha OS=Rattus no... 80.5 3e-14
sp|Q5RDH5|AAPK1_PONAB 5'-AMP-activated protein kinase catalytic s... 80.9 3e-14
sp|Q41639|CDC2_VIGAC Cell division control protein 2 homolog OS=V... 78.2 3e-14
sp|P53349|M3K1_MOUSE Mitogen-activated protein kinase kinase kina... 81.6 3e-14
sp|Q753D9|PKH3_EREGS Serine/threonine-protein kinase PKH3 OS=Erem... 81.3 3e-14
sp|Q2V419|CKB12_ARATH Cyclin-dependent kinase B1-2 OS=Arabidopsis... 78.6 3e-14
sp|Q9XEC8|CRK38_ARATH Cysteine-rich receptor-like protein kinase ... 81.3 3e-14
sp|Q9SA72|Y1357_ARATH Probable receptor-like protein kinase At1g3... 81.3 3e-14
sp|P18652|KS6AA_CHICK Ribosomal protein S6 kinase 2 alpha OS=Gall... 81.3 3e-14
sp|Q8BZN4|NUAK2_MOUSE NUAK family SNF1-like kinase 2 OS=Mus muscu... 80.9 3e-14
sp|P57058|HUNK_HUMAN Hormonally up-regulated neu tumor-associated... 81.3 3e-14
sp|Q75V57|SAPK9_ORYSJ Serine/threonine-protein kinase SAPK9 OS=Or... 79.3 3e-14
sp|Q7Z2Y5|NRK_HUMAN Nik-related protein kinase OS=Homo sapiens OX... 81.6 3e-14
sp|O08644|EPHB6_MOUSE Ephrin type-B receptor 6 OS=Mus musculus OX... 81.6 3e-14
sp|Q9LN59|WAKLK_ARATH Putative wall-associated receptor kinase-li... 81.3 3e-14
sp|Q15349|KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 OS=Homo... 81.3 3e-14
sp|P06244|KAPA_YEAST cAMP-dependent protein kinase type 1 OS=Sacc... 79.7 3e-14
sp|Q99JP0|M4K3_MOUSE Mitogen-activated protein kinase kinase kina... 81.3 4e-14
sp|O04534|LRK51_ARATH Putative L-type lectin-domain containing re... 80.9 4e-14
sp|Q9SYS7|CRK39_ARATH Putative cysteine-rich receptor-like protei... 80.9 4e-14
sp|Q6BNF3|STE20_DEBHA Serine/threonine-protein kinase STE20 OS=De... 81.3 4e-14
sp|Q75H77|SAPKA_ORYSJ Serine/threonine-protein kinase SAPK10 OS=O... 79.3 4e-14
sp|Q9SA25|WAKLG_ARATH Wall-associated receptor kinase-like 8 OS=A... 80.9 4e-14
sp|Q9Y884|SKH1_SCHPO MAP kinase kinase skh1/pek1 OS=Schizosacchar... 79.0 4e-14
sp|C0LGG7|Y1534_ARATH Probable LRR receptor-like serine/threonine... 81.3 4e-14
sp|A0A1D6E0S8|WAK17_MAIZE Wall-associated receptor kinase 17 OS=Z... 81.3 4e-14
sp|O65472|CRK12_ARATH Putative cysteine-rich receptor-like protei... 80.9 4e-14
sp|Q8IVH8|M4K3_HUMAN Mitogen-activated protein kinase kinase kina... 81.3 4e-14
sp|Q8RY67|WAKLO_ARATH Wall-associated receptor kinase-like 14 OS=... 80.9 4e-14
sp|O15111|IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase s... 80.9 4e-14
sp|Q8CFH6|SIK2_MOUSE Serine/threonine-protein kinase SIK2 OS=Mus ... 81.3 4e-14
sp|Q8GYQ5|MPK12_ARATH Mitogen-activated protein kinase 12 OS=Arab... 79.0 4e-14
sp|Q6C3D7|STE20_YARLI Serine/threonine-protein kinase STE20 OS=Ya... 81.3 4e-14
sp|Q9LDI3|CIPKO_ARATH CBL-interacting serine/threonine-protein ki... 79.7 5e-14
sp|Q21029|NSY1_CAEEL Mitogen-activated protein kinase kinase kina... 81.3 5e-14
sp|Q54GY6|KXCA_DICDI Kinase and exchange factor for Rac A OS=Dict... 81.3 5e-14
sp|P34556|CDK1_CAEEL Cyclin-dependent kinase 1 OS=Caenorhabditis ... 78.6 5e-14
sp|Q6PDN3|MYLK_MOUSE Myosin light chain kinase, smooth muscle OS=... 81.3 5e-14
sp|Q62925|M3K1_RAT Mitogen-activated protein kinase kinase kinase... 81.3 5e-14
sp|Q5REX1|SIK2_PONAB Serine/threonine-protein kinase SIK2 OS=Pong... 80.9 5e-14
sp|Q7X8C5|WAKLB_ARATH Wall-associated receptor kinase-like 2 OS=A... 80.5 5e-14
sp|Q39202|RLK1_ARATH G-type lectin S-receptor-like serine/threoni... 80.5 5e-14
sp|P50528|PLO1_SCHPO Serine/threonine-protein kinase plo1 OS=Schi... 80.5 5e-14
sp|Q52EB3|ATG1_PYRO7 Serine/threonine-protein kinase ATG1 OS=Pyri... 80.9 5e-14
sp|A9TF79|SRK2A_PHYPA Serine/threonine-protein kinase SRK2A OS=Ph... 78.6 5e-14
sp|P34101|FHKC_DICDI Probable serine/threonine-protein kinase fhk... 80.1 5e-14
sp|Q8N5S9|KKCC1_HUMAN Calcium/calmodulin-dependent protein kinase... 79.7 5e-14
sp|Q9LUL4|SRF7_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 7 OS=Arab... 80.5 5e-14
sp|Q9DG98|CDK1_ORYLU Cyclin-dependent kinase 1 OS=Oryzias luzonen... 77.8 6e-14
sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS... 80.9 6e-14
sp|Q21734|KS6A1_CAEEL Putative ribosomal protein S6 kinase alpha-... 80.5 6e-14
sp|G4N6Z6|MKK2_PYRO7 Mitogen-activated protein kinase kinae MKK2 ... 79.7 6e-14
sp|Q9DGD3|CDK1_ORYLA Cyclin-dependent kinase 1 OS=Oryzias latipes... 77.8 6e-14
sp|Q95KV1|IKKA_BOVIN Inhibitor of nuclear factor kappa-B kinase s... 80.5 6e-14
sp|Q9LIG2|RLK6_ARATH Receptor-like protein kinase At3g21340 OS=Ar... 80.5 6e-14
sp|Q69JN6|BRL1_ORYSJ Brassinosteroid LRR receptor kinase BRL1 OS=... 80.9 6e-14
sp|Q9SYM9|Y1853_ARATH Receptor-like serine/threonine-protein kina... 78.6 6e-14
sp|Q9SI06|Y5573_ARATH Putative leucine-rich repeat receptor-like ... 80.5 6e-14
sp|Q5XIT0|CDKL2_RAT Cyclin-dependent kinase-like 2 OS=Rattus norv... 79.7 6e-14
sp|Q38773|CDC2B_ANTMA Cell division control protein 2 homolog B (... 77.4 6e-14
sp|Q8BGW6|ST32A_MOUSE Serine/threonine-protein kinase 32A OS=Mus ... 79.0 6e-14
sp|Q6ZCZ2|BRL3_ORYSJ Brassinosteroid LRR receptor kinase BRL3 OS=... 80.9 6e-14
sp|Q9M345|LRK42_ARATH L-type lectin-domain containing receptor ki... 80.1 6e-14
sp|O65405|CRK28_ARATH Cysteine-rich receptor-like protein kinase ... 80.1 6e-14
sp|Q54XX5|Y9849_DICDI Probable serine/threonine-protein kinase DD... 80.5 6e-14
sp|Q9TZM3|LRK1_CAEEL Leucine-rich repeat serine/threonine-protein... 80.9 6e-14
sp|Q8VBY2|KKCC1_MOUSE Calcium/calmodulin-dependent protein kinase... 79.7 6e-14
sp|P52389|CDC2_VIGUN Cell division control protein 2 homolog OS=V... 77.4 6e-14
sp|Q6EU49|WNK4_ORYSJ Probable serine/threonine-protein kinase WNK... 80.1 6e-14
sp|Q9DGA2|CDK1_ORYJA Cyclin-dependent kinase 1 OS=Oryzias javanic... 77.4 6e-14
sp|O49717|CDPKF_ARATH Calcium-dependent protein kinase 15 OS=Arab... 79.7 7e-14
sp|Q8GUQ5|BRI1_SOLLC Brassinosteroid LRR receptor kinase OS=Solan... 80.5 7e-14
sp|Q02723|RKIN1_SECCE Carbon catabolite-derepressing protein kina... 79.7 7e-14
sp|Q7Z8E9|STE20_PYRO7 Serine/threonine-protein kinase MST20 OS=Py... 80.5 7e-14
sp|Q9LX29|ACR4L_ARATH Serine/threonine-protein kinase-like protei... 80.5 7e-14
sp|P97756|KKCC1_RAT Calcium/calmodulin-dependent protein kinase k... 79.7 7e-14
sp|O64784|Y1136_ARATH G-type lectin S-receptor-like serine/threon... 80.5 7e-14
sp|Q9LJF3|BRL3_ARATH Receptor-like protein kinase BRI1-like 3 OS=... 80.5 7e-14
sp|F4ICB6|IBS1_ARATH Protein IMPAIRED IN BABA-INDUCED STERILITY 1... 80.1 7e-14
sp|P87253|KPC1_NEUCR Protein kinase C-like OS=Neurospora crassa (... 80.5 7e-14
sp|Q8SQW2|CTK1_ENCCU Probable CTD kinase subunit alpha homolog OS... 77.8 7e-14
sp|P10666|KS6AB_XENLA Ribosomal protein S6 kinase 2 beta OS=Xenop... 79.7 8e-14
sp|O81069|Y2899_ARATH Probable leucine-rich repeat receptor-like ... 80.1 8e-14
sp|Q2NL51|GSK3A_MOUSE Glycogen synthase kinase-3 alpha OS=Mus mus... 79.3 8e-14
sp|P34117|CDK5_DICDI Cyclin-dependent kinase 5 homolog OS=Dictyos... 77.0 8e-14
sp|P50526|SSP1_SCHPO Serine/threonine-protein kinase ssp1 OS=Schi... 79.7 8e-14
sp|P51817|PRKX_HUMAN cAMP-dependent protein kinase catalytic subu... 78.2 8e-14
sp|Q5YJC2|GSK3B_SPECI Glycogen synthase kinase-3 beta OS=Spermoph... 79.0 8e-14
sp|Q9FZB8|Y5181_ARATH Probable LRR receptor-like serine/threonine... 80.1 8e-14
sp|A8X6H4|CMK1_CAEBR Calcium/calmodulin-dependent protein kinase ... 78.2 8e-14
sp|Q55GG4|Y9847_DICDI Probable serine/threonine-protein kinase DD... 80.5 8e-14
sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo... 80.1 8e-14
sp|O54784|DAPK3_MOUSE Death-associated protein kinase 3 OS=Mus mu... 79.0 8e-14
sp|Q9C7T7|CEPR2_ARATH Receptor protein-tyrosine kinase CEPR2 OS=A... 80.1 8e-14
sp|Q9SKB2|SBIR1_ARATH Leucine-rich repeat receptor-like serine/th... 79.7 8e-14
sp|Q7XR88|STRK1_ORYSJ Salt tolerance receptor-like cytoplasmic ki... 78.2 8e-14
sp|A2XW02|STRK1_ORYSI Salt tolerance receptor-like cytoplasmic ki... 78.2 8e-14
sp|P48609|CDK5_DROME Cyclin-dependent kinase 5 homolog OS=Drosoph... 77.0 8e-14
sp|P49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta OS=Homo sap... 78.6 8e-14
sp|Q14164|IKKE_HUMAN Inhibitor of nuclear factor kappa-B kinase s... 79.7 8e-14
sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo... 79.7 9e-14
sp|O95819|M4K4_HUMAN Mitogen-activated protein kinase kinase kina... 80.5 9e-14
sp|P18654|KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 OS=Mus ... 79.7 9e-14
sp|Q9WV60|GSK3B_MOUSE Glycogen synthase kinase-3 beta OS=Mus musc... 78.6 9e-14
sp|P28867|KPCD_MOUSE Protein kinase C delta type OS=Mus musculus ... 79.7 9e-14
sp|P54666|CC2H3_TRYBB Cell division control protein 2 homolog 3 O... 77.4 9e-14
sp|Q9C8I6|IOS1_ARATH LRR receptor-like serine/threonine-protein k... 80.1 9e-14
sp|Q9QUK0|CDKL2_MOUSE Cyclin-dependent kinase-like 2 OS=Mus muscu... 79.3 9e-14
sp|Q93Z30|BHP_ARATH Serine/threonine-protein kinase 12 OS=Arabido... 79.0 9e-14
sp|Q8BG48|ST17B_MOUSE Serine/threonine-protein kinase 17B OS=Mus ... 78.2 9e-14
sp|Q8VYA3|WAKLJ_ARATH Wall-associated receptor kinase-like 10 OS=... 79.7 9e-14
sp|O88764|DAPK3_RAT Death-associated protein kinase 3 OS=Rattus n... 79.0 9e-14
sp|Q9TTK0|CDKL2_RABIT Cyclin-dependent kinase-like 2 OS=Oryctolag... 79.3 9e-14
sp|Q55DD4|PAKD_DICDI Serine/threonine-protein kinase pakD OS=Dict... 80.1 9e-14
sp|P12965|MOS_XENLA Serine/threonine-protein kinase mos OS=Xenopu... 77.8 9e-14
sp|O22932|CIPKB_ARATH CBL-interacting serine/threonine-protein ki... 78.6 1e-13
sp|Q8C0V7|SMKW_MOUSE Putative sperm motility kinase W OS=Mus musc... 79.0 1e-13
sp|P06493|CDK1_HUMAN Cyclin-dependent kinase 1 OS=Homo sapiens OX... 77.0 1e-13
sp|Q8S8Y9|WNK2_ARATH Serine/threonine-protein kinase WNK2 OS=Arab... 79.3 1e-13
sp|P48734|CDK1_BOVIN Cyclin-dependent kinase 1 OS=Bos taurus OX=9... 77.0 1e-13
sp|Q12469|SKM1_YEAST Serine/threonine-protein kinase SKM1 OS=Sacc... 79.7 1e-13
sp|Q93ZS4|NIK3_ARATH Protein NSP-INTERACTING KINASE 3 OS=Arabidop... 79.3 1e-13
sp|Q9FJ54|CIPKK_ARATH CBL-interacting serine/threonine-protein ki... 78.6 1e-13
sp|Q7Y0B9|SAPK8_ORYSJ Serine/threonine-protein kinase SAPK8 OS=Or... 77.8 1e-13
sp|P93101|CDC2_OXYRB Cell division control protein 2 homolog OS=O... 76.6 1e-13
sp|P35567|CDK1A_XENLA Cyclin-dependent kinase 1-A OS=Xenopus laev... 77.0 1e-13
sp|Q55CL6|MP2K1_DICDI Dual specificity mitogen-activated protein ... 79.3 1e-13
sp|X5M8U1|GCY17_CAEEL Receptor-type guanylate cyclase gcy-17 OS=C... 79.7 1e-13
sp|Q5WA76|PUB70_ORYSJ U-box domain-containing protein 70 OS=Oryza... 79.7 1e-13
sp|P23572|CDK1_DROME Cyclin-dependent kinase 1 OS=Drosophila mela... 76.6 1e-13
sp|Q8SRU0|CSK2A_ENCCU Probable casein kinase II subunit alpha hom... 77.0 1e-13
sp|Q5N942|SAPK4_ORYSJ Serine/threonine-protein kinase SAPK4 OS=Or... 77.8 1e-13
sp|P28582|CDPK_DAUCA Calcium-dependent protein kinase OS=Daucus c... 79.0 1e-13
sp|Q03002|FRK1_YEAST Fatty acyl-CoA synthetase and RNA processing... 79.7 1e-13
sp|Q6FN53|STE20_CANGA Serine/threonine-protein kinase STE20 OS=Ca... 79.7 1e-13
sp|Q92772|CDKL2_HUMAN Cyclin-dependent kinase-like 2 OS=Homo sapi... 78.6 1e-13
sp|Q16975|KPC2_APLCA Calcium-independent protein kinase C OS=Aply... 79.3 1e-13
sp|P19525|E2AK2_HUMAN Interferon-induced, double-stranded RNA-act... 79.0 1e-13
sp|O81292|LRK43_ARATH L-type lectin-domain containing receptor ki... 79.3 1e-13
sp|Q8VYY5|NCRK_ARATH Receptor-like serine/threonine-protein kinas... 79.0 1e-13
sp|Q940H6|SRK2E_ARATH Serine/threonine-protein kinase SRK2E OS=Ar... 77.4 1e-13
sp|Q5R754|CDKL2_PONAB Cyclin-dependent kinase-like 2 OS=Pongo abe... 78.6 1e-13
sp|Q8IBS5|CDPK4_PLAF7 Calcium-dependent protein kinase 4 OS=Plasm... 79.0 1e-13
sp|O23082|CRK44_ARATH Cysteine-rich receptor-like protein kinase ... 77.8 1e-13
sp|Q9S7U9|M2K2_ARATH Mitogen-activated protein kinase kinase 2 OS... 77.4 1e-13
sp|Q4R7T5|CDKL2_MACFA Cyclin-dependent kinase-like 2 OS=Macaca fa... 79.0 1e-13
sp|Q99014|KPC1_HYPJE Protein kinase C-like OS=Hypocrea jecorina O... 79.7 1e-13
sp|Q54WW7|Y0010_DICDI Probable serine/threonine-protein kinase DD... 79.3 1e-13
sp|Q2PQN9|CDK5_GLOMM Cyclin-dependent kinase 5 homolog OS=Glossin... 76.3 1e-13
sp|Q9FXF2|RKF1_ARATH Probable LRR receptor-like serine/threonine-... 79.7 1e-13
sp|P83510|TNIK_MOUSE Traf2 and NCK-interacting protein kinase OS=... 79.7 1e-13
sp|Q9FIF1|LRK21_ARATH Probable L-type lectin-domain containing re... 79.3 1e-13
sp|O95382|M3K6_HUMAN Mitogen-activated protein kinase kinase kina... 79.7 1e-13
sp|Q39086|SD17_ARATH Receptor-like serine/threonine-protein kinas... 79.3 1e-13
sp|Q9FHG4|LRKS7_ARATH Probable L-type lectin-domain containing re... 79.0 1e-13
sp|Q9DGA5|CDK1_ORYCU Cyclin-dependent kinase 1 OS=Oryzias curvino... 76.6 1e-13
sp|P11681|ABL_CALVI Tyrosine-protein kinase ABL (Fragment) OS=Cal... 70.1 1e-13
sp|Q9IA88|SIK2_CHICK Serine/threonine-protein kinase SIK2 OS=Gall... 79.3 1e-13
sp|O49318|Y2317_ARATH Probable leucine-rich repeat receptor-like ... 79.3 1e-13
sp|Q9FIF0|LRK22_ARATH Putative L-type lectin-domain containing re... 79.0 1e-13
sp|P0C5D6|SAPK3_ORYSJ Serine/threonine-protein kinase SAPK3 OS=Or... 77.0 1e-13
sp|A2ZAB5|SAPK3_ORYSI Serine/threonine-protein kinase SAPK3 OS=Or... 77.0 1e-13
sp|Q9XEC7|CRK37_ARATH Cysteine-rich receptor-like protein kinase ... 79.0 1e-13
sp|P39951|CDK1_RAT Cyclin-dependent kinase 1 OS=Rattus norvegicus... 76.3 1e-13
sp|Q9SN43|CIPKC_ARATH CBL-interacting serine/threonine-protein ki... 78.6 1e-13
sp|Q5BBL3|STE20_EMENI Serine/threonine-protein kinase ste20 OS=Em... 79.3 1e-13
sp|P11440|CDK1_MOUSE Cyclin-dependent kinase 1 OS=Mus musculus OX... 76.3 1e-13
sp|Q9ZVM9|Y1461_ARATH Probable serine/threonine-protein kinase At... 78.6 1e-13
sp|Q7XUF4|CDKG2_ORYSJ Cyclin-dependent kinase G-2 OS=Oryza sativa... 79.0 1e-13
sp|A2XUW1|CDKG2_ORYSI Cyclin-dependent kinase G-2 OS=Oryza sativa... 79.0 1e-13
sp|Q940A2|P2C31_ARATH Protein kinase and PP2C-like domain-contain... 79.0 2e-13
sp|O74536|SNF1_SCHPO SNF1-like protein kinase ssp2 OS=Schizosacch... 78.6 2e-13
sp|Q8H1D6|RBK1_ARATH Receptor-like cytosolic serine/threonine-pro... 78.2 2e-13
sp|Q6ICW6|WNK11_ARATH Probable serine/threonine-protein kinase WN... 76.6 2e-13
>sp|P29597|TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2
OS=Homo sapiens OX=9606 GN=TYK2 PE=1 SV=3
Length=1187
Score = 2455 bits (6362), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1187/1187 (100%), Positives = 1187/1187 (100%), Gaps = 0/1187 (0%)
Query 1 MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI 60
MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI
Sbjct 1 MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI 60
Query 61 AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREP 120
AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREP
Sbjct 61 AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREP 120
Query 121 AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFK 180
AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFK
Sbjct 121 AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFK 180
Query 181 NESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRR 240
NESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRR
Sbjct 181 NESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRR 240
Query 241 FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP 300
FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP
Sbjct 241 FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP 300
Query 301 TDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHK 360
TDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHK
Sbjct 301 TDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHK 360
Query 361 AVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLV 420
AVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLV
Sbjct 361 AVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLV 420
Query 421 DGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP 480
DGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP
Sbjct 421 DGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP 480
Query 481 YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA 540
YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA
Sbjct 481 YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA 540
Query 541 GDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTR 600
GDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTR
Sbjct 541 GDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTR 600
Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660
TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS
Sbjct 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS
Sbjct 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780
ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA
Sbjct 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840
PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ
Sbjct 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI
Sbjct 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII
Sbjct 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI
Sbjct 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY
Sbjct 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC
Sbjct 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC 1187
PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC
Sbjct 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC 1187
>sp|Q9R117|TYK2_MOUSE Non-receptor tyrosine-protein kinase TYK2
OS=Mus musculus OX=10090 GN=Tyk2 PE=1 SV=3
Length=1184
Score = 1919 bits (4970), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 939/1177 (80%), Positives = 1023/1177 (87%), Gaps = 10/1177 (1%)
Query 12 SKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCF 71
SK G AQP+ G L VLLHW GP GGEPWVTFS++SLTAEEVCIHIAHKVGITPPC
Sbjct 17 SKADGTEAQPLVPTGCLMVLLHWPGPEGGEPWVTFSQTSLTAEEVCIHIAHKVGITPPCL 76
Query 72 NLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTE 131
NLFAL++AQA+VWLPPNHIL+ +D + LYFR+RFYFRNWHGMNP+EPAVYRCG PG E
Sbjct 77 NLFALYNAQAKVWLPPNHILDTSQD--MNLYFRMRFYFRNWHGMNPQEPAVYRCGFPGAE 134
Query 132 ASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHL 191
SSD+ QG+QLLD ASFEYLFEQGKHEF+NDV SL +LS+EEEIHHFKNESLGMAFLHL
Sbjct 135 TSSDRAEQGVQLLDSASFEYLFEQGKHEFMNDVVSLRDLSSEEEIHHFKNESLGMAFLHL 194
Query 192 CHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLS 251
CHLAL G+PLEE+A++ SFK+CIP SFR+HIRQH+ LTRLRL VFRRFLR F+PG LS
Sbjct 195 CHLALSRGVPLEEMAREISFKNCIPHSFRQHIRQHNVLTRLRLHRVFRRFLRAFRPGHLS 254
Query 252 QQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGP 311
QQ+VMVKYLATLERLAPRFG+ER+PVCHL +LAQ E +PCYI++SG DPGPE +GP
Sbjct 255 QQVVMVKYLATLERLAPRFGSERIPVCHLEVLAQPERDPCYIQNSGQTAGDPGPELPSGP 314
Query 312 PTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPRE 371
PTHEVLVTGTGGIQW P++ +E G+S NP S GKK KA KA + P+E
Sbjct 315 PTHEVLVTGTGGIQWHPLQ----TQESERGNSRGNPHGSRSGKKPKAPKAGEHLTESPQE 370
Query 372 PLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSS 431
P W YFCDF+DI+HVVLKE V IH QDNKCL L L S+A ALSFV+LVDGYFRLTADSS
Sbjct 371 PPWTYFCDFQDISHVVLKERRVHIHLQDNKCLLLCLCSQAEALSFVALVDGYFRLTADSS 430
Query 432 HYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRS 491
HYLCHEVAPPRLV SI++GIHGPL++PFVQAKL PEDGLYLI WSTSH +RLILTVA R+
Sbjct 431 HYLCHEVAPPRLVTSIQNGIHGPLMDPFVQAKLWPEDGLYLIQWSTSHLHRLILTVAHRN 490
Query 492 QA-PDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRC 550
A +G + LRLRKFPI QQ GAFVL+GWGRSF S+ +L ALQGC LRAGDDCF L C
Sbjct 491 PAFSNGPRGLRLRKFPITQQPGAFVLDGWGRSFASLGDLRLALQGCSLRAGDDCFPLHHC 550
Query 551 CLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRV 610
CLP+P E SNL+IMRG+RA R LNLSQLSFHRV Q EITQLSHLGQGTRTNVYEG LRV
Sbjct 551 CLPRPREISNLVIMRGSRAHTRPLNLSQLSFHRVHQDEITQLSHLGQGTRTNVYEGLLRV 610
Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670
G P+EGK+D+ P PG GQ+LRVVLKVLDPSHHDIALAFYETASLMSQVSH HL
Sbjct 611 ---GGPDEGKVDNGCPPEPGGTSGQQLRVVLKVLDPSHHDIALAFYETASLMSQVSHMHL 667
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730
AF+HGVCVRG ENI+VTE+VEHGPLDVWLRR+RG VPM WKMVVAQQLASALSYLE+KNL
Sbjct 668 AFLHGVCVRGSENIIVTEFVEHGPLDVWLRRQRGQVPMTWKMVVAQQLASALSYLEDKNL 727
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANS 790
VHGNVCGRNILLARLGL EGT+PFIKLSDPGVG GALSREERVERIPW APECL GG +S
Sbjct 728 VHGNVCGRNILLARLGLEEGTNPFIKLSDPGVGQGALSREERVERIPWTAPECLSGGTSS 787
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLT 850
L TA D WGFGATLLEICFDGEAPLQ R PSEKE FY ++H+LPEPS P+LATLT QCLT
Sbjct 788 LGTATDMWGFGATLLEICFDGEAPLQGRGPSEKERFYTKKHQLPEPSSPELATLTRQCLT 847
Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910
YEP QRPSFRTILRDLTRLQP NL VN DSPASDPTVFHKRYLKKIRDLGEGHFGK
Sbjct 848 YEPAQRPSFRTILRDLTRLQPQNLVGTSAVNSDSPASDPTVFHKRYLKKIRDLGEGHFGK 907
Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970
VSLYCYDPTNDGTGEMVAVKALK CGPQ RSGW++EI+ILRTLYHEHI+KYKGCCEDQG
Sbjct 908 VSLYCYDPTNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVKYKGCCEDQG 967
Query 971 EKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030
EKS+QLVMEYVPLGSLRDYLPRH +GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL
Sbjct 968 EKSVQLVMEYVPLGSLRDYLPRHCVGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1027
Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE KFYYASDVWSFGVT
Sbjct 1028 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSFGVT 1087
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
LYELLT+CDS+QSP KF ELIG QGQMTVLRLTELLERGERLPRPD+CPCE+YHLMKN
Sbjct 1088 LYELLTYCDSNQSPHMKFTELIGHTQGQMTVLRLTELLERGERLPRPDRCPCEIYHLMKN 1147
Query 1151 CWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC 1187
CWETEASFRPTF+NL+PIL+T EKYQGQ PSVFSVC
Sbjct 1148 CWETEASFRPTFQNLVPILQTAQEKYQGQVPSVFSVC 1184
>sp|P23458|JAK1_HUMAN Tyrosine-protein kinase JAK1 OS=Homo sapiens
OX=9606 GN=JAK1 PE=1 SV=2
Length=1154
Score = 1014 bits (2623), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 529/1130 (47%), Positives = 724/1130 (64%), Gaps = 54/1130 (5%)
Query 52 TAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRN 111
TAEE+CI A I+P C NLFAL+D ++W PN + + SL L++R+RFYF N
Sbjct 56 TAEELCIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTN 115
Query 112 WHGMNPREPAVYRCGPPGTEASSDQTA--QGMQLLDPASFEYLFEQGKHEFVNDVASLWE 169
WHG N E +V+R P + ++ LLD +S EYLF QG+++ V +A + +
Sbjct 116 WHGTNDNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRD 175
Query 170 LSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSAL 229
TE++ H +NE LGMA L + H A+ + L E+ K S+K IP + + IRQ + L
Sbjct 176 PKTEQDGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLL 235
Query 230 TRLRLRNVFRRFLRDFQ-----PGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLA 284
TR+R+ NVF+ FL++F +S + VKYLATLE L +G E L + +
Sbjct 236 TRMRINNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISS 295
Query 285 QAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSG 344
+ E + D G +EV+VTG GIQW + + + S
Sbjct 296 ENEMNWFHSNDGG------------NVLYYEVMVTGNLGIQW--------RHKPNVVSVE 335
Query 345 RNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLE 404
+ K HK + ++ RE W F F +ITH+V+KE VSI++QDNK +E
Sbjct 336 KEKNKLKRKKLENKHKK-DEEKNKIREE-WNNFSYFPEITHIVIKESVVSINKQDNKKME 393
Query 405 LSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKL 464
L L S ALSFVSLVDGYFRLTAD+ HYLC +VAPP +V +I++G HGP+ + KL
Sbjct 394 LKLSSHEEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKL 453
Query 465 R---PEDGLYLIHWSTSHPYRLILTVA--QRSQAPDGMQSLRLRKFPIEQQDGAFVLEGW 519
R E+G+Y++ WS + +++TV ++S+ G Q + + F IE Q G + L G
Sbjct 454 RQEGSEEGMYVLRWSCTDFDNILMTVTCFEKSEQVQGAQK-QFKNFQIEVQKGRYSLHGS 512
Query 520 GRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLII-MRGARASPRTLNLSQ 578
RSFPS+ +L + L+ +LR + F L+RCC P+P E SNL++ + A+ +SQ
Sbjct 513 DRSFPSLGDLMSHLKKQILRTDNISFMLKRCCQPKPREISNLLVATKKAQEWQPVYPMSQ 572
Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
LSF R+ +K++ Q HLG+GTRT++Y G L MD +D G ++++
Sbjct 573 LSFDRILKKDLVQGEHLGRGTRTHIYSGTL------------MDYKDD--EGTSEEKKIK 618
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V+LKVLDPSH DI+LAF+E AS+M QVSH H+ +++GVCVR ENIMV E+VE GPLD++
Sbjct 619 VILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLF 678
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ R+ + WK VA+QLASALSYLE+K+LVHGNVC +N+LLAR G+ PFIKLS
Sbjct 679 MHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSECGPFIKLS 738
Query 759 DPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
DPG+ + LSR+E +ERIPW+APEC+ N LS A DKW FG TL EIC++GE PL+ +
Sbjct 739 DPGIPITVLSRQECIERIPWIAPECVEDSKN-LSVAADKWSFGTTLWEICYNGEIPLKDK 797
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ EKE FY+ + R PSC +LA L ++C+ Y+P QRP FR I+RD+ +L+ N D++
Sbjct 798 TLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQN-PDIV 856
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
+ + DPT F KR+LK+IRDLGEGHFGKV L YDP D TGE VAVK+LK + G
Sbjct 857 SEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGG 916
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IG 996
H + K+EI+ILR LYHE+I+KYKG C + G ++L+ME++P GSL++YLP++ I
Sbjct 917 NHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKIN 976
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
L Q L +A QIC+GM YL ++ Y+HRDLAARNVL++++ VKIGDFGL KA+ EYY
Sbjct 977 LKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYT 1036
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
V++D DSPVFWYAPECL + KFY ASDVWSFGVTL+ELLT+CDS SP FL++IG
Sbjct 1037 VKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTH 1096
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
GQMTV RL L+ G+RLP P CP EVY LM+ CWE + S R +F+NLI
Sbjct 1097 GQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLI 1146
Score = 68.9 bits (167), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 66/289 (23%), Positives = 126/289 (44%), Gaps = 39/289 (13%)
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQV 665
R+R G G + ++ DP G + G++ V +K L P +A + ++ +
Sbjct 877 RIRDLGEGHFGKVELCRYDP--EGDNTGEQ--VAVKSLKPESGGNHIADLKKEIEILRNL 932
Query 666 SHTHLAFVHGVCVRGPEN--IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723
H ++ G+C N ++ E++ G L +L + + + + ++ A Q+ +
Sbjct 933 YHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMD 992
Query 724 YLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS-------REERVERI 776
YL ++ VH ++ RN+L+ + +K+ D G+ + +++R +
Sbjct 993 YLGSRQYVHRDLAARNVLVE-------SEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPV 1045
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEI---CFDGEAP----LQSRSPSEKEHFYQR 829
W APECL + A D W FG TL E+ C +P L+ P+ + R
Sbjct 1046 FWYAPECL--MQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTR 1103
Query 830 -------QHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
RLP P+CP ++ L +C ++P+ R SF+ ++ L
Sbjct 1104 LVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEAL 1152
>sp|P52332|JAK1_MOUSE Tyrosine-protein kinase JAK1 OS=Mus musculus
OX=10090 GN=Jak1 PE=1 SV=1
Length=1153
Score = 1013 bits (2619), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 529/1130 (47%), Positives = 728/1130 (64%), Gaps = 55/1130 (5%)
Query 52 TAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRN 111
TAEE+CI A + I+P C NLFAL+D ++W PN I+ + SL L++R+RFYF N
Sbjct 56 TAEELCIRAAQECSISPLCHNLFALYDESTKLWYAPNRIITVDDKTSLRLHYRMRFYFTN 115
Query 112 WHGMNPREPAVYRCGPPGTEASSDQ--TAQGMQLLDPASFEYLFEQGKHEFVNDVASLWE 169
WHG N E +V+R P + ++ + LLD +S EYLF QG+++ + +A + +
Sbjct 116 WHGTNDNEQSVWRHSPKKQKNGYEKKRVPEATPLLDASSLEYLFAQGQYDLIKCLAPIRD 175
Query 170 LSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSAL 229
TE++ H +NE LGMA L + H A+ + L E+ K S+K IP + + IRQ + L
Sbjct 176 PKTEQDGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLL 235
Query 230 TRLRLRNVFRRFLRDFQPGRLSQQMV---MVKYLATLER--LAPRFGTERVPVCHLRLLA 284
TR+R+ NVF+ FL++F + V VKYLATLE L +G E L + +
Sbjct 236 TRMRINNVFKDFLKEFNNKTICDSSVHDLKVKYLATLETSTLTKHYGAEIFETSMLLISS 295
Query 285 QAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSG 344
+ E C+ DSG +EV+VTG GIQW ++ N +
Sbjct 296 ENELSRCHSNDSGNV-------------LYEVMVTGNLGIQW---RQKPNVVPVEKEKNK 339
Query 345 RNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLE 404
+ + K K ++ RE W F F +ITH+V+KE VSI++QDNK +E
Sbjct 340 LKRKKLEYNKHKK-----DDERNKLREE-WNNFSYFPEITHIVIKESVVSINKQDNKNME 393
Query 405 LSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKL 464
L L SR ALSFVSLVDGYFRLTAD+ HYLC +VAPP +V +I++G HGP+ + KL
Sbjct 394 LKLSSREEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKL 453
Query 465 R---PEDGLYLIHWSTSHPYRLILTVA--QRSQAPDGMQSLRLRKFPIEQQDGAFVLEGW 519
R E+G+Y++ WS + +++TV ++S+ G + + + F IE Q G + L G
Sbjct 454 RQEGSEEGMYVLRWSCTDFDNILMTVTCFEKSEVLGGQK--QFKNFQIEVQKGRYSLHGS 511
Query 520 GRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLII-MRGARASPRTLNLSQ 578
FPS+R+L L+ +LR + F L+RCC P+P E SNL++ + A+ ++SQ
Sbjct 512 MDHFPSLRDLMNHLKKQILRTDNISFVLKRCCQPKPREISNLLVATKKAQEWQPVYSMSQ 571
Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
LSF R+ +K+I Q HLG+GTRT++Y G L +D +D G ++++
Sbjct 572 LSFDRILKKDIIQGEHLGRGTRTHIYSGTL------------LDYKDE--EGIAEEKKIK 617
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V+LKVLDPSH DI+LAF+E AS+M QVSH H+ +++GVCVR ENIMV E+VE GPLD++
Sbjct 618 VILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLF 677
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ R+ + WK VA+QLASALSYLE+K+LVHGNVC +N+LLAR G+ PFIKLS
Sbjct 678 MHRKSDALTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSDIGPFIKLS 737
Query 759 DPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
DPG+ + L+R+E +ERIPW+APEC+ N LS A DKW FG TL EIC++GE PL+ +
Sbjct 738 DPGIPVSVLTRQECIERIPWIAPECVEDSKN-LSVAADKWSFGTTLWEICYNGEIPLKDK 796
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ EKE FY+ + R PSC +LA L ++C+ Y+P QRP FR I+RD+ +L+ N D++
Sbjct 797 TLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQN-PDIV 855
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
+ + DPT F KR+LK+IRDLGEGHFGKV L YDP D TGE VAVK+LK + G
Sbjct 856 SEKQPTTEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGG 915
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IG 996
H + K+EI+ILR LYHE+I+KYKG C + G ++L+ME++P GSL++YLP++ I
Sbjct 916 NHIADLKKEIEILRNLYHENIVKYKGICMEDGGNGIKLIMEFLPSGSLKEYLPKNKNKIN 975
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
L Q L +A QIC+GM YL ++ Y+HRDLAARNVL++++ VKIGDFGL KA+ EYY
Sbjct 976 LKQQLKYAIQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYT 1035
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
V++D DSPVFWYAPECL + KFY ASDVWSFGVTL+ELLT+CDS SP FL++IG
Sbjct 1036 VKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDFSPMALFLKMIGPTH 1095
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
GQMTV RL + L+ G+RLP P CP EVY LM+ CWE + S R TF+NLI
Sbjct 1096 GQMTVTRLVKTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTTFQNLI 1145
>sp|O12990|JAK1_DANRE Tyrosine-protein kinase JAK1 OS=Danio rerio
OX=7955 GN=jak1 PE=1 SV=1
Length=1153
Score = 990 bits (2560), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 535/1162 (46%), Positives = 730/1162 (63%), Gaps = 65/1162 (6%)
Query 23 AAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQ 82
AM GL++ + A E F ++ TAE++C+ A + I+P C NLFAL++
Sbjct 29 TAMKGLEIHFYLADTHQLE----FFKACYTAEDLCVEAAKRCRISPLCHNLFALYEESQD 84
Query 83 VWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYR--CGPPGTEASSDQTAQG 140
+W PNH+ ++ + S+ L++R+RFYF NWHG + E V+R + +S +T +G
Sbjct 85 LWYAPNHVFKVTDETSIKLHYRMRFYFTNWHGTSEIESPVWRHTLSKQKSVLNSQKTTEG 144
Query 141 MQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGI 200
LLD AS +YLF QG+++F+ ++ + T+EE H +NE LGMA L + H A + +
Sbjct 145 TPLLDAASLDYLFAQGQYDFLRGLSPVRPTQTDEEHHEIENECLGMAVLAITHHAKSNNL 204
Query 201 PLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMV----- 255
PL +TS+K IP S R I+Q + LTR+R+ NVF+ FL +F + +
Sbjct 205 PLSGAGAETSYKRFIPDSLNRTIKQRNFLTRIRISNVFKNFLNEFNSKTIQDSNIGLYDL 264
Query 256 MVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHE 315
VKYL+TLE L G E +L++ ++EG P A P ++ G +E
Sbjct 265 KVKYLSTLETLTQGVGREIFKPKNLKVTGESEGSP--------AQMLPLGDNGMG---YE 313
Query 316 VLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVG--QPADRPREPL 373
V V GT GI W P + K K+ K G Q D+ ++
Sbjct 314 VQVYGTTGISW---------------RRKPAPNQLILKDKPKSKKIKGDKQWNDKKKDSG 358
Query 374 WAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHY 433
W F DF +ITH+V+K+ CV+I+RQDNK +EL L R AALSF +LVDGYFRLT D+ HY
Sbjct 359 WTLFSDFHEITHIVIKDCCVTIYRQDNKTMELDLFYRDAALSFAALVDGYFRLTVDAHHY 418
Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWS-TSHPYRLILTVAQ 489
LC +VAP +V ++ +G HGP+ + KLR E +G Y++ WS T + + ++ V
Sbjct 419 LCTDVAPSSVVQNLENGCHGPICTEYAIHKLRQEGNEEGTYVLRWSCTEYNFIIMTVVCI 478
Query 490 RSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRR 549
+ + + F IE + L G P+++EL LQG LLR + F LRR
Sbjct 479 ELDLCESRPVPQYKNFQIETSPQGYRLYGTDTFRPTLKELLEHLQGQLLRTDNLRFQLRR 538
Query 550 CCLPQPGETSNLIIMRGAR--ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
CC PQP E SNL++M R + +SQLSF R+ ++EI Q HLG+GTRTN+Y G
Sbjct 539 CCPPQPREISNLLVMTTDREPVPQKKTQVSQLSFDRILKEEIVQGEHLGRGTRTNIYAGI 598
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667
L+ K DDED L QE++VVLKVL H DI+LAF+ETAS+M Q+SH
Sbjct 599 LK---------PKSDDEDDL---GGYSQEVKVVLKVLGSGHRDISLAFFETASMMRQISH 646
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
H A ++GVCVR ENIMV E+V++GPLD+++RR+ + AWK VA+QLASALSYLE+
Sbjct 647 KHTALLYGVCVRHQENIMVEEFVQYGPLDLFMRRQTTPLSTAWKFQVAKQLASALSYLED 706
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGG 787
K +VHG VC +NIL+AR GL PFIKLSDPG+ + LSREE V+RIPW+APEC+
Sbjct 707 KKMVHGYVCSKNILVARDGLDGEGGPFIKLSDPGIPITVLSREECVDRIPWIAPECVKDT 766
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ 847
AN L+ A DKW FG TL EIC++GE PL+ + SEKE FY Q +L P C +LA L +
Sbjct 767 AN-LTIAADKWSFGTTLWEICYNGEIPLKDKKLSEKERFYAAQCQLATPDCDELAKLMTH 825
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS-DPTVFHKRYLKKIRDLGEG 906
C+TY+P QR FR I+RD+ ++ N + + P DPTVF KR+LKKIRDLGEG
Sbjct 826 CMTYDPRQRLFFRAIVRDIVMVEKQNPS----IQPVPMLEVDPTVFEKRFLKKIRDLGEG 881
Query 907 HFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC 966
HFGKV L YDP D TGE+VAVK+LK + + + +EI ILR LYHE+I+KYKG C
Sbjct 882 HFGKVELCRYDPRGDRTGELVAVKSLKPENREEQSNNLWREIHILRELYHENIVKYKGIC 941
Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDL 1024
++G +S++L+ME++P GSL++YLPR+ I L L ++ QIC+GM YL +++YIHRDL
Sbjct 942 NEEGGRSIKLIMEFLPAGSLKEYLPRNKAHINLKTLHNYSVQICQGMDYLGSRNYIHRDL 1001
Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084
AARNVL++N+ VKIGDFGL K++ + YY V++D DSPVFWYAPECL KFY ASDV
Sbjct 1002 AARNVLVENEGTVKIGDFGLTKSIKDNEGYYTVKDDLDSPVFWYAPECLIHCKFYRASDV 1061
Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144
WSFGVT+YELLT+CD+S SP + FL+LIG GQMTV RL ++LE G+RLPRPD C ++
Sbjct 1062 WSFGVTMYELLTYCDASCSPMSVFLKLIGPTHGQMTVTRLVKVLEEGKRLPRPDDCSEQL 1121
Query 1145 YHLMKNCWETEASFRPTFENLI 1166
Y+LM+ CWE R F++LI
Sbjct 1122 YNLMRRCWEATPEKRIDFKSLI 1143
>sp|Q09178|JAK1_CYPCA Tyrosine-protein kinase JAK1 OS=Cyprinus
carpio OX=7962 GN=jak1 PE=2 SV=1
Length=1156
Score = 920 bits (2379), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 520/1169 (44%), Positives = 708/1169 (61%), Gaps = 74/1169 (6%)
Query 22 MAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCF-NLFALFDAQ 80
+ M GL++ H+ P + + + + TAE++C+ + + C NLFAL +
Sbjct 28 LTVMKGLEI--HFYLPDTHQ--LEYFKDCHTAEDLCVEGCQEDATSHLCADNLFALSEES 83
Query 81 AQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCG--PPGTEASSDQTA 138
+W PNH +I + S+ L++R+RFYF NWH E V+R + S +
Sbjct 84 QDLWYAPNHAFKITEETSIKLHYRMRFYFTNWHAPVRTESPVWRHSLFKHKGVSVSPKGP 143
Query 139 QGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRH 198
+G LLD AS EYLF QG+++F+ +A + E E H +NE LGMA L + H A +
Sbjct 144 EGTPLLDAASLEYLFAQGQYDFLRGLAPVRAPQNEAEKHEIENECLGMAVLAITHHAKSN 203
Query 199 GIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDF-----QPGRLSQQ 253
+PL V +TS+K IP S R I+Q + NVF+ FL +F Q ++
Sbjct 204 DLPLSGVGAETSYKRFIPDSLNRTIKQRNFSHVYVYNNVFKNFLNEFNSKTIQDSNITLY 263
Query 254 MVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPT 313
+ VKYL+TLE L G E + L++ +++G P A T P + G
Sbjct 264 DLKVKYLSTLETLTQGLGRETIEPKILKVSGESDGSP--------ALTLPSGDDGLG--- 312
Query 314 HEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLF-------GKKAKAHKAVGQPA 366
+EV V+GT GI W R P ++ KK KA K +
Sbjct 313 YEVQVSGTTGISW-----------------RRKPVPNILIVKDKTKSKKNKADKQSKKEM 355
Query 367 DRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRL 426
+ R+ + F DF +ITH+V+KE C +I+ QDNK +EL L R AALSF +LVDGYFRL
Sbjct 356 TK-RKTVMTIFSDFFEITHIVIKESCATIYSQDNKTMELDLFYRDAALSFAALVDGYFRL 414
Query 427 TADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWS-TSHPYR 482
T D+ HYLC EVAP +V ++ +G HGP+ + KLR E +G Y++ WS T + Y
Sbjct 415 TVDAHHYLCTEVAPSSVVQNLENGCHGPICTEYAIHKLRQEGNEEGTYVLRWSCTDYNYI 474
Query 483 LILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGD 542
++ V + + + F IE + L G P+++EL LQG LR +
Sbjct 475 IMTVVCIEMDLCESRPVPQYKNFQIETSPQGYRLYGTDTFRPTLKELLEHLQGQNLRTEN 534
Query 543 DCFSLRRCCLPQPGETSNLIIMRGARA--SPRTLNLSQLSFHRVDQKEITQLSHLGQGTR 600
F L QP + SNL++M R S R +SQLSFHR+ ++EI Q HLG+GTR
Sbjct 535 LRFQPVLVGLGQPRKISNLLVMTRDREPDSQRQPQVSQLSFHRILKEEIVQGEHLGRGTR 594
Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660
TN+Y G L+++ D + G QE++V+LKVL H DI+LAF+ETAS
Sbjct 595 TNIYSGVLKLKSEDDDDMGGY------------SQEVKVILKVLGSGHRDISLAFFETAS 642
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
+M Q+SH H+A ++GVCVR ENIMV E+V++GPLD+++RR+ + AWK VA+QLA
Sbjct 643 MMRQISHKHIALLYGVCVRHQENIMVEEFVQYGPLDLFMRRQSIPLSTAWKFQVAKQLAG 702
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780
ALSYLE+K LVHGNVC +NIL+AR GL PFIKLSDPG+ + LSREE V+R+PW+A
Sbjct 703 ALSYLEDKKLVHGNVCSKNILVARDGLDGEGGPFIKLSDPGIPITVLSREECVDRLPWIA 762
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840
PEC+ AN LS A DKWGFG TL EIC++GE PL+ + +EKE FY Q +L P C +
Sbjct 763 PECVQDTAN-LSIAADKWGFGTTLWEICYNGEIPLKDKKLTEKERFYAAQCQLASPDCEE 821
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS-DPTVFHKRYLKK 899
LA L + C+TY+P QR FR I+RD+ ++ N + + P DPTVF KR+LKK
Sbjct 822 LAKLMTHCMTYDPRQRLFFRAIVRDIDMVEKQNPS----IQPVPMLEVDPTVFEKRFLKK 877
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
IRDLGEGHFGKV L YDP D TGE+VAVK+LK + + S +EI ILR LYHE+I
Sbjct 878 IRDLGEGHFGKVELCRYDPRGDRTGELVAVKSLKPENREEQSSNLWREIHILRELYHENI 937
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQ 1017
+KYKG ++G +S++L+ME++P GSL++YLPR+ I L LL +A QIC+GM L ++
Sbjct 938 VKYKGIWHEEGGRSIKLIMEFLPAGSLKEYLPRNKAHIDLKTLLNYAVQICQGMDLLASR 997
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+YIHRDLAARNVL++N+ VKIGDFGL K++ + YY V++D DSPVFWYAPECL K
Sbjct 998 NYIHRDLAARNVLVENENTVKIGDFGLTKSIKDNEGYYTVKDDLDSPVFWYAPECLIHCK 1057
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
FY ASDVWSFGVT+YELLT+CD S SP + FL +IG GQMTV RL ++LE G+RLP+P
Sbjct 1058 FYRASDVWSFGVTMYELLTYCDISCSPMSVFLTMIGPTHGQMTVTRLVKVLEEGKRLPKP 1117
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
D C +Y LM+ CWE R F+ LI
Sbjct 1118 DGCSDRLYCLMRRCWEATPEKRIDFKGLI 1146
>sp|Q75R65|JAK2_CHICK Tyrosine-protein kinase JAK2 OS=Gallus gallus
OX=9031 GN=JAK2 PE=2 SV=1
Length=1129
Score = 781 bits (2017), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 453/1204 (38%), Positives = 649/1204 (54%), Gaps = 138/1204 (11%)
Query 15 VGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLF 74
+G+ + P L+V L+++ G ++ F AEE+CI GI P N+F
Sbjct 24 LGNTSAPKQTEPLLQVYLYYSPGKTGGDYLQFPAGEYVAEEICIVACKACGIMPVYHNMF 83
Query 75 ALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASS 134
AL +VW PPNHI + L L +RIRFYF +W+ Y G+E+
Sbjct 84 ALMSETERVWYPPNHIFHVDEATRLKLLYRIRFYFPHWYCNGTSRACRYGI-IRGSESP- 141
Query 135 DQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHL 194
+LD YLF Q + +F++ + H + E LGMA L + +
Sbjct 142 --------VLDDLVMSYLFAQWRKDFLDGWIQM------PVTHETQEECLGMAVLDMMRV 187
Query 195 ALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQM 254
A V S+K +P+ R I+++ LTR R+R FR+F++ F + + +
Sbjct 188 AKEKDQTPLAVYNSVSYKMFLPKCVRAKIQEYHILTRKRIRYRFRKFIQQFGQCKATARN 247
Query 255 VMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTH 314
+ +KYL LE L F +E V +PG + +
Sbjct 248 LKLKYLINLETLQSAFYSEVFEV-----------------------KEPGGDPSGEESFA 284
Query 315 EVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLW 374
+++TG GGIQ S G+ ++
Sbjct 285 TIVITGNGGIQC---------------SRGKLKNCETLAEQD-----------------L 312
Query 375 AYFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFR 425
+CDF DI V +K+ V+IH+QD+K LE S ALSFVSL+DGY+R
Sbjct 313 QTYCDFPDIIDVSIKQASQEGSSERRIVTIHKQDSKNLEAEFQSLREALSFVSLIDGYYR 372
Query 426 LTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYR 482
LTAD+ HYLC EVAPP ++ +I+ HGP+ F KL+ + G Y++ S +
Sbjct 373 LTADAHHYLCKEVAPPSVLENIQSNCHGPIFMDFAINKLKKAGNQTGFYVLRCSPKDFKK 432
Query 483 LILTVA-QRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAG 541
LT A +R A D L + ++G + L G RSF ++++L Q +R+
Sbjct 433 YFLTFAIERENATDYKHCLITK-----NENGEYNLSGTKRSFGNLKDLLTCYQTETVRSD 487
Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASP-------RTLNLSQLSFHRVDQKEITQLSH 594
F +CC P+P + SNL++ R S + N+SQ+ FH++ +++
Sbjct 488 SIIFQFIKCCPPKPKDKSNLLVFRSNSVSDVPSSPTLQRHNVSQMVFHKIRNEDLIFEES 547
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ--ELRVVLKVLDPSHHDIA 652
LGQGT T +++G + G D GQ + V+LKVLD H + +
Sbjct 548 LGQGTFTKIFKGIRKEVG-------------------DYGQLHQTEVLLKVLDKVHRNYS 588
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
+F+E AS+MSQ+S+ HL +GVCV G ENI+V EYV+ G LD +L++ + + + WK+
Sbjct 589 ESFFEAASMMSQLSYKHLVLNYGVCVCGEENILVQEYVKFGSLDTYLKKNKNVINILWKL 648
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARL-GLAEGTSPFIKLSDPGVGLGALSREE 771
VA+QLA A+ +LE+K LVHGNVC +NILL R G PFIKLSDPG+ + L R+
Sbjct 649 EVAKQLALAMHFLEDKGLVHGNVCAKNILLIREEDRKSGNLPFIKLSDPGISITVLPRDI 708
Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
+ERIPW+ PEC+ LS A DKW FG TL EIC G+ PL + S K FY+ +H
Sbjct 709 LLERIPWVPPECIEN-PRQLSLATDKWSFGTTLWEICSGGDKPLSALDSSRKLQFYEDRH 767
Query 832 RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA----- 886
+LP P+ +LA L + C+ YEP RPSFR I+RDL L + ++LT N P
Sbjct 768 QLPAPNWTELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDY-ELLTENDMLPNIRTGA 826
Query 887 ---------SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L+
Sbjct 827 LGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST- 885
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL 997
+H +++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H L
Sbjct 886 EEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERL 945
Query 998 --AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+LLL+A QIC+GM YL + Y+HRDLA RN+L++N+ VKIGDFGL K +P+ EYY
Sbjct 946 DHKKLLLYASQICKGMEYLGTKRYVHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYY 1005
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI- 1114
+V+E G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG
Sbjct 1006 KVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGND 1065
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
QGQM V L ELL+ RLPRPD CP E+Y +MK CW + RPTF +L + + +
Sbjct 1066 KQGQMIVFHLIELLKNNGRLPRPDGCPDEIYAIMKECWNNNVAQRPTFRDLAQRVDQIRD 1125
Query 1175 KYQG 1178
G
Sbjct 1126 NMGG 1129
>sp|Q62689|JAK2_RAT Tyrosine-protein kinase JAK2 OS=Rattus norvegicus
OX=10116 GN=Jak2 PE=1 SV=1
Length=1132
Score = 765 bits (1976), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 451/1180 (38%), Positives = 641/1180 (54%), Gaps = 148/1180 (13%)
Query 31 LLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHI 90
L H G G+ ++ F AEE+C+ + GITP N+FAL ++W PPNH+
Sbjct 43 LYHSLGQAEGD-YLKFPNGEYVAEEICVAASKACGITPVYHNMFALMSETERIWYPPNHV 101
Query 91 LEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPP-GTEASSDQTAQGMQLLDPASF 149
I + +RIRFYF +W+ YR G G EA LLD
Sbjct 102 FHIDESTRHNILYRIRFYFPHWYCSGSNR--TYRYGVSRGAEAP---------LLDDFVM 150
Query 150 EYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKT 209
YLF Q +H+FV+ + H + E LGMA L + +A V
Sbjct 151 SYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLDMMRIAKEKDQTPLAVYNSI 204
Query 210 SFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPR 269
S+K +P+ R I+ + LTR R+R FRRF++ F + + + + +KYL LE L
Sbjct 205 SYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNLKLKYLINLETLQSA 264
Query 270 FGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEV----LVTGTGGIQ 325
F TE+ V ESA GP E+ ++TG GGIQ
Sbjct 265 FYTEQFEV---------------------------KESARGPSGEEIFATIIITGNGGIQ 297
Query 326 WWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITH 385
W S G++ ++ ++ +CDF DI
Sbjct 298 W---------------SRGKHKESETLTEQD-----------------LQLYCDFPDIID 325
Query 386 VVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCH 436
V +K+ V++H+QD K LE+ L S ALSFVSL+DGY+RLTAD+ HYLC
Sbjct 326 VSIKQANQECSTESRVVTVHKQDGKVLEIELSSLKEALSFVSLIDGYYRLTADAHHYLCK 385
Query 437 EVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQA 493
EVAPP ++ +I HGP+ F +KL+ + GLY++ S + LT A +
Sbjct 386 EVAPPAVLENIHSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVEREN 445
Query 494 PDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLP 553
+ + K ++G + L G R+F S+++L Q +R+ F +CC P
Sbjct 446 VIEYKHCLITK----NENGEYNLSGTKRNFSSLKDLLNCYQMETVRSDSIIFQFTKCCPP 501
Query 554 QPGETSNLIIMRGARASPRTL--------NLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605
+P + SNL++ R S L N++Q+ FH++ +++ LGQGT T +++
Sbjct 502 KPKDKSNLLVFRTNGVSDVQLSPTLQRHNNVNQMVFHKIRNEDLIFNESLGQGTFTKIFK 561
Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ--ELRVVLKVLDPSHHDIALAFYETASLMS 663
G R G D GQ E V+LKVLD +H + + +F+E AS+MS
Sbjct 562 GVRREVG-------------------DYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS 602
Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723
Q+SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+ VA+QLA A+
Sbjct 603 QLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLGVAKQLAWAMH 662
Query 724 YLENKNLVHGNVCGRNILLARL-GLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPE 782
+LE K+L+HGNVC +NILL R G PFIKLSDPG+ + L ++ ERIPW+ PE
Sbjct 663 FLEEKSLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE 722
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLA 842
C+ N L+ A DKW FG TL EIC G+ PL + K FY+ +H+LP P +LA
Sbjct 723 CIENPKN-LTLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDKHQLPAPKWTELA 781
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA--------------SD 888
L + C+ YEP RP+FR ++RDL L + ++LT N P D
Sbjct 782 NLINTCMDYEPDFRPAFRAVIRDLNSLFTPDY-ELLTENDMLPNMRIGALGFSGAFEDRD 840
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
PT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L+ +H +++EI
Sbjct 841 PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST-EEHLRDFEREI 899
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006
+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I +LL + Q
Sbjct 900 EILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQ 959
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
IC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V+E G+SP+F
Sbjct 960 ICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIF 1019
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQGQMTVLRLT 1125
WYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG QGQM V L
Sbjct 1020 WYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDKQGQMIVFHLI 1079
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
ELL+ RLPRP+ CP E+Y +M CW + RP+F +L
Sbjct 1080 ELLKNNGRLPRPEGCPDEIYVIMTECWNNNVNQRPSFRDL 1119
Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 92/361 (25%), Positives = 163/361 (45%), Gaps = 56/361 (16%)
Query 837 SCPQLATLTSQCLTYEPTQ----RPSFRTILRDLTRLQPHNLADVLTVNPD---SPASDP 889
+C Q+ T+ S + ++ T+ +P ++ +L + + ++DV ++P +
Sbjct 479 NCYQMETVRSDSIIFQFTKCCPPKPKDKS---NLLVFRTNGVSDV-QLSPTLQRHNNVNQ 534
Query 890 TVFHKRYLKKI---RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS---G 943
VFHK + + LG+G F K+ D G++ + L HR+
Sbjct 535 MVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGD-YGQLHETEVLLKVLDKAHRNYSES 593
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLL 1001
+ + ++ L H+H++ G C GE+++ LV E+V GSL YL ++ SI + L
Sbjct 594 FFEAASMMSQLSHKHLVLNYGVCV-CGEENI-LVQEFVKFGSLDTYLKKNKNSINILWKL 651
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL--DNDR------LVKIGDFGLAKAV-PEGH 1052
A+Q+ M +L + IH ++ A+N+LL + DR +K+ D G++ V P+
Sbjct 652 GVAKQLAWAMHFLEEKSLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDI 711
Query 1053 EYYRVREDGDSPVFWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111
R+ W PEC++ K A+D WSFG TL+E+ C P +
Sbjct 712 LQERIP--------WVPPECIENPKNLTLATDKWSFGTTLWEI---CSGGDKPLSA---- 756
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ R + E +LP P E+ +L+ C + E FRP F +I L +
Sbjct 757 -------LDSQRKLQFYEDKHQLPAPKWT--ELANLINTCMDYEPDFRPAFRAVIRDLNS 807
Query 1172 V 1172
+
Sbjct 808 L 808
>sp|Q62120|JAK2_MOUSE Tyrosine-protein kinase JAK2 OS=Mus musculus
OX=10090 GN=Jak2 PE=1 SV=3
Length=1132
Score = 764 bits (1973), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 452/1180 (38%), Positives = 643/1180 (54%), Gaps = 148/1180 (13%)
Query 31 LLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHI 90
L H G GE ++ F AEE+C+ + GITP N+FAL ++W PPNH+
Sbjct 43 LYHSLGQAEGE-YLKFPSGEYVAEEICVAASKACGITPVYHNMFALMSETERIWYPPNHV 101
Query 91 LEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPP-GTEASSDQTAQGMQLLDPASF 149
I + +RIRFYF +W+ YR G G EA LLD
Sbjct 102 FHIDESTRHDILYRIRFYFPHWYCSGSSR--TYRYGVSRGAEAP---------LLDDFVM 150
Query 150 EYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKT 209
YLF Q +H+FV+ + H + E LGMA L + +A V
Sbjct 151 SYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLDMMRIAKEKDQTPLAVYNSV 204
Query 210 SFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPR 269
S+K +P+ R I+ + LTR R+R FRRF++ F + + + + +KYL LE L
Sbjct 205 SYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNLKLKYLINLETLQSA 264
Query 270 FGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEV----LVTGTGGIQ 325
F TE+ V ESA GP E+ ++TG GGIQ
Sbjct 265 FYTEQFEV---------------------------KESARGPSGEEIFATIIITGNGGIQ 297
Query 326 WWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITH 385
W S G++ ++ ++ +CDF DI
Sbjct 298 W---------------SRGKHKESETLTEQDVQ-----------------LYCDFPDIID 325
Query 386 VVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCH 436
V +K+ V++H+QD K LE+ L S ALSFVSL+DGY+RLTAD+ HYLC
Sbjct 326 VSIKQANQECSNESRIVTVHKQDGKVLEIELSSLKEALSFVSLIDGYYRLTADAHHYLCK 385
Query 437 EVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQA 493
EVAPP ++ +I HGP+ F +KL+ + GLY++ S + LT A +
Sbjct 386 EVAPPAVLENIHSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVEREN 445
Query 494 PDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLP 553
+ + K ++G + L G R+F ++++L Q +R+ F +CC P
Sbjct 446 VIEYKHCLITK----NENGEYNLSGTKRNFSNLKDLLNCYQMETVRSDSIIFQFTKCCPP 501
Query 554 QPGETSNLIIMR-----GARASP---RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605
+P + SNL++ R + SP R N++Q+ FH++ +++ LGQGT T +++
Sbjct 502 KPKDKSNLLVFRTNGISDVQISPTLQRHNNVNQMVFHKIRNEDLIFNESLGQGTFTKIFK 561
Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ--ELRVVLKVLDPSHHDIALAFYETASLMS 663
G R G D GQ + V+LKVLD +H + + +F+E AS+MS
Sbjct 562 GVRREVG-------------------DYGQLHKTEVLLKVLDKAHRNYSESFFEAASMMS 602
Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723
Q+SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+ VA+QLA A+
Sbjct 603 QLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLGVAKQLAWAMH 662
Query 724 YLENKNLVHGNVCGRNILLARL-GLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPE 782
+LE K+L+HGNVC +NILL R G PFIKLSDPG+ + L ++ ERIPW+ PE
Sbjct 663 FLEEKSLIHGNVCAKNILLIREEDRRTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE 722
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLA 842
C+ N L+ A DKW FG TL EIC G+ PL + K FY+ +H+LP P +LA
Sbjct 723 CIENPKN-LNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDKHQLPAPKWTELA 781
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA--------------SD 888
L + C+ YEP RP+FR ++RDL L + ++LT N P D
Sbjct 782 NLINNCMDYEPDFRPAFRAVIRDLNSLFTPDY-ELLTENDMLPNMRIGALGFSGAFEDRD 840
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
PT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L+ +H +++EI
Sbjct 841 PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST-EEHLRDFEREI 899
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006
+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I +LL + Q
Sbjct 900 EILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQ 959
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
IC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V+E G+SP+F
Sbjct 960 ICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIF 1019
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQGQMTVLRLT 1125
WYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG QGQM V L
Sbjct 1020 WYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDKQGQMIVFHLI 1079
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
ELL+ RLPRP+ CP E+Y +M CW S RP+F +L
Sbjct 1080 ELLKSNGRLPRPEGCPDEIYVIMTECWNNNVSQRPSFRDL 1119
Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 93/361 (26%), Positives = 164/361 (45%), Gaps = 56/361 (16%)
Query 837 SCPQLATLTSQCLTYEPTQ----RPSFRTILRDLTRLQPHNLADVLTVNPD---SPASDP 889
+C Q+ T+ S + ++ T+ +P ++ +L + + ++DV ++P +
Sbjct 479 NCYQMETVRSDSIIFQFTKCCPPKPKDKS---NLLVFRTNGISDV-QISPTLQRHNNVNQ 534
Query 890 TVFHKRYLKKI---RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS---G 943
VFHK + + LG+G F K+ D G++ + L HR+
Sbjct 535 MVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGD-YGQLHKTEVLLKVLDKAHRNYSES 593
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLL 1001
+ + ++ L H+H++ G C GE+++ LV E+V GSL YL ++ SI + L
Sbjct 594 FFEAASMMSQLSHKHLVLNYGVCV-CGEENI-LVQEFVKFGSLDTYLKKNKNSINILWKL 651
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL--DNDR------LVKIGDFGLAKAV-PEGH 1052
A+Q+ M +L + IH ++ A+N+LL + DR +K+ D G++ V P+
Sbjct 652 GVAKQLAWAMHFLEEKSLIHGNVCAKNILLIREEDRRTGNPPFIKLSDPGISITVLPKDI 711
Query 1053 EYYRVREDGDSPVFWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111
R+ W PEC++ K A+D WSFG TL+E+ C P +
Sbjct 712 LQERIP--------WVPPECIENPKNLNLATDKWSFGTTLWEI---CSGGDKPLSA---- 756
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ R + E +LP P E+ +L+ NC + E FRP F +I L +
Sbjct 757 -------LDSQRKLQFYEDKHQLPAPKWT--ELANLINNCMDYEPDFRPAFRAVIRDLNS 807
Query 1172 V 1172
+
Sbjct 808 L 808
>sp|Q5RB23|JAK2_PONAB Tyrosine-protein kinase JAK2 OS=Pongo abelii
OX=9601 GN=JAK2 PE=2 SV=1
Length=1132
Score = 759 bits (1960), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 452/1208 (37%), Positives = 654/1208 (54%), Gaps = 144/1208 (12%)
Query 15 VGDGAQPMAAMGGLKVLLHWAGPGGGEP-WVTFSESSLTAEEVCIHIAHKVGITPPCFNL 73
+ A M + + ++ + G E ++TF AEE+CI + GITP N+
Sbjct 25 ISGNANSMKQIDPVLLVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNM 84
Query 74 FALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWH--GMNPREPAVYRCGPP-GT 130
FAL ++W PPNH+ I + +RIRFYF W+ G N YR G G
Sbjct 85 FALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPRWYCSGSN----RAYRHGISRGA 140
Query 131 EASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLH 190
EA LLD YLF Q +H+FV+ + H + E LGMA L
Sbjct 141 EAP---------LLDDFVMSYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLD 185
Query 191 LCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRL 250
+ +A + + S+K +P+ R I+ + LTR R+R FRRF++ F +
Sbjct 186 MMRIAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKA 245
Query 251 SQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAG 310
+ + + +KYL LE L F TE+ V ++ G P+ G E A
Sbjct 246 TARNLKLKYLINLETLQSAFYTEKFEV----------------KEPGSGPS--GEEIFAT 287
Query 311 PPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPR 370
+++TG GGIQW S G++ ++ ++
Sbjct 288 -----IIITGNGGIQW---------------SRGKHKESETLTEQD-------------- 313
Query 371 EPLWAYFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVD 421
+CDF +I V +K+ V+IH+QD K LE+ L S ALSFVSL+D
Sbjct 314 ---LQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREALSFVSLID 370
Query 422 GYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTS 478
GY+RLTAD+ HYLC EVAPP ++ +I+ HGP+ F +KL+ + GLY++ S
Sbjct 371 GYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPK 430
Query 479 HPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLL 538
+ LT A + + + K ++ + L G ++F S+++L Q +
Sbjct 431 DFNKYFLTFAVERENVIEYKHCLITK----NENEEYNLSGTKKNFSSLKDLLNCYQMETV 486
Query 539 RAGDDCFSLRRCCLPQPGETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEIT 590
R+ + F +CC P+P + SNL++ R S R +++Q+ FH++ +++
Sbjct 487 RSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLI 546
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ--ELRVVLKVLDPSH 648
LGQGT T +++G R G D GQ E V+LKVLD +H
Sbjct 547 FNESLGQGTFTKIFKGVRREVG-------------------DYGQLHETEVLLKVLDKAH 587
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ + +F+E AS+MS++SH HL +GVCV G ENI+V E+V+ G LD +L++ + + +
Sbjct 588 RNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINI 647
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL-GLAEGTSPFIKLSDPGVGLGAL 767
WK+ VA+QLA A+ +LE L+HGNVC +NILL R G PFIKLSDPG+ + L
Sbjct 648 LWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVL 707
Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
++ ERIPW+ PEC+ N L+ A DKW FG TL EIC G+ PL + K FY
Sbjct 708 PKDILQERIPWVPPECIENPKN-LNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFY 766
Query 828 QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA- 886
+ +H+LP P +LA L + C+ YEP RPSFR I+RDL L + ++LT N P
Sbjct 767 EDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDY-ELLTENDMLPNM 825
Query 887 -------------SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933
DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L+
Sbjct 826 RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQ 885
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993
+H +++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H
Sbjct 886 HST-EEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKH 944
Query 994 S--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
I +LL + QIC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+
Sbjct 945 KERIDHKKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQD 1004
Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111
EYY+V+E G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +
Sbjct 1005 KEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRM 1064
Query 1112 IGI-AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
IG QGQM V L ELL+ RLPRPD CP E+Y +M CW + RP+F +L +
Sbjct 1065 IGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVD 1124
Query 1171 TVHEKYQG 1178
+ + G
Sbjct 1125 QIRDNMAG 1132
>sp|O60674|JAK2_HUMAN Tyrosine-protein kinase JAK2 OS=Homo sapiens
OX=9606 GN=JAK2 PE=1 SV=2
Length=1132
Score = 759 bits (1960), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 451/1194 (38%), Positives = 650/1194 (54%), Gaps = 143/1194 (12%)
Query 28 LKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPP 87
L+V L+ + ++TF AEE+CI + GITP N+FAL ++W PP
Sbjct 39 LQVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNMFALMSETERIWYPP 98
Query 88 NHILEIPRDASLMLYFRIRFYFRNWH--GMNPREPAVYRCGPP-GTEASSDQTAQGMQLL 144
NH+ I + +RIRFYF W+ G N YR G G EA LL
Sbjct 99 NHVFHIDESTRHNVLYRIRFYFPRWYCSGSN----RAYRHGISRGAEAP---------LL 145
Query 145 DPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEE 204
D YLF Q +H+FV+ + H + E LGMA L + +A +
Sbjct 146 DDFVMSYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLDMMRIAKENDQTPLA 199
Query 205 VAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLE 264
+ S+K +P+ R I+ + LTR R+R FRRF++ F + + + + +KYL LE
Sbjct 200 IYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNLKLKYLINLE 259
Query 265 RLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGI 324
L F TE+ V ++ G P+ G E A +++TG GGI
Sbjct 260 TLQSAFYTEKFEV----------------KEPGSGPS--GEEIFAT-----IIITGNGGI 296
Query 325 QWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDIT 384
QW S G++ ++ ++ +CDF +I
Sbjct 297 QW---------------SRGKHKESETLTEQD-----------------LQLYCDFPNII 324
Query 385 HVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLC 435
V +K+ V+IH+QD K LE+ L S ALSFVSL+DGY+RLTAD+ HYLC
Sbjct 325 DVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYYRLTADAHHYLC 384
Query 436 HEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQ 492
EVAPP ++ +I+ HGP+ F +KL+ + GLY++ S + LT A +
Sbjct 385 KEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERE 444
Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552
+ + K ++ + L G ++F S+++L Q +R+ + F +CC
Sbjct 445 NVIEYKHCLITK----NENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCP 500
Query 553 PQPGETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVY 604
P+P + SNL++ R S R +++Q+ FH++ +++ LGQGT T ++
Sbjct 501 PKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIF 560
Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ--ELRVVLKVLDPSHHDIALAFYETASLM 662
+G R G D GQ E V+LKVLD +H + + +F+E AS+M
Sbjct 561 KGVRREVG-------------------DYGQLHETEVLLKVLDKAHRNYSESFFEAASMM 601
Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASAL 722
S++SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+ VA+QLA A+
Sbjct 602 SKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAM 661
Query 723 SYLENKNLVHGNVCGRNILLARL-GLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781
+LE L+HGNVC +NILL R G PFIKLSDPG+ + L ++ ERIPW+ P
Sbjct 662 HFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP 721
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL 841
EC+ N L+ A DKW FG TL EIC G+ PL + K FY+ +H+LP P +L
Sbjct 722 ECIENPKN-LNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAEL 780
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA--------------S 887
A L + C+ YEP RPSFR I+RDL L + ++LT N P
Sbjct 781 ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDY-ELLTENDMLPNMRIGALGFSGAFEDR 839
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L+ +H +++E
Sbjct 840 DPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST-EEHLRDFERE 898
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQ 1005
I+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I +LL +
Sbjct 899 IEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTS 958
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
QIC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V+E G+SP+
Sbjct 959 QICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPI 1018
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQGQMTVLRL 1124
FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG QGQM V L
Sbjct 1019 FWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHL 1078
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
ELL+ RLPRPD CP E+Y +M CW + RP+F +L + + + G
Sbjct 1079 IELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG 1132
>sp|O19064|JAK2_PIG Tyrosine-protein kinase JAK2 OS=Sus scrofa
OX=9823 GN=JAK2 PE=2 SV=1
Length=1131
Score = 759 bits (1959), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 450/1178 (38%), Positives = 644/1178 (55%), Gaps = 144/1178 (12%)
Query 31 LLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHI 90
L H G G+ ++ F AEE+C+ + GITP ++FAL + ++W PPNH+
Sbjct 43 LYHSLGKAEGD-YLKFPAGEYVAEEICVAASKACGITPVYHSMFALMNETERIWYPPNHV 101
Query 91 LEIPRDASLMLYFRIRFYFRNWH--GMNPREPAVYRCG-PPGTEASSDQTAQGMQLLDPA 147
+ + +RIRFYF W+ G N YR G G EA LLD
Sbjct 102 FHVDESTRHNVLYRIRFYFPYWYCNGSN----RTYRHGISRGAEAP---------LLDDF 148
Query 148 SFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAK 207
YLF Q +H+F L+ H + E LGMA L + +A ++
Sbjct 149 VMSYLFAQWRHDF------LYGWVKIPVTHETQEECLGMAVLDMMRIAKEKDQTPLDIYS 202
Query 208 KTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLA 267
S+K +P+ R I+ + LTR R+R FRRF+ F + + + + +KYL LE L
Sbjct 203 SVSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQFSHCKATARNLKLKYLINLETLQ 262
Query 268 PRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWW 327
F TE+ V ++ G P+ G E A +++TG GGIQW
Sbjct 263 SAFYTEQFEV----------------KEPGRGPS--GEEIFAT-----IIITGNGGIQW- 298
Query 328 PVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVV 387
S G++ ++ ++ +CDF DI V
Sbjct 299 --------------SRGKHKESETLTEQD-----------------LQLYCDFPDIIDVS 327
Query 388 LKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEV 438
+K+ V+IH+QD K LE+ L S ALSFVSL+DGY+RLTAD+ HYLC EV
Sbjct 328 IKQANQEGSNESRIVTIHKQDGKSLEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEV 387
Query 439 APPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPD 495
APP ++ +I+ HGP+ F +KL+ + GL+++ S + LT A +
Sbjct 388 APPMVLENIQSNCHGPISMDFAISKLKKAGNQTGLFVLRCSPKDFNKYFLTFAVERENVT 447
Query 496 GMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQP 555
+ + K ++G + L G ++F ++++L Q +R+ F +CC P+P
Sbjct 448 EYKHCLITK----NENGEYNLSGTRKNFSNLKDLLNCYQMETVRSDSIIFQFTKCCPPKP 503
Query 556 GETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
+ SNL++ R S R N++Q+ FH++ +++ LGQGT T +++G
Sbjct 504 KDKSNLLVFRTNGISDVPTSPTLQRHNNVNQMVFHKIRNEDLIFNESLGQGTFTKIFKGV 563
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQ--ELRVVLKVLDPSHHDIALAFYETASLMSQV 665
R G D GQ E V+LKVLD +H + + +F+E AS+MSQ+
Sbjct 564 RREVG-------------------DYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSQL 604
Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL 725
SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+ VA+QLA A+ +L
Sbjct 605 SHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWAMHFL 664
Query 726 ENKNLVHGNVCGRNILLARL-GLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECL 784
E K L+HGNVC +NILL R G PFIKLSDPG+ + L ++ ERIPW+ PEC+
Sbjct 665 EEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECI 724
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATL 844
N L+ A DKW FG TL EIC G+ PL + K FY+ +H+LP P +LA L
Sbjct 725 ENPKN-LNLATDKWSFGTTLWEICSGGDKPLNALDSQRKLQFYEDRHQLPAPKWTELANL 783
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA--------------SDPT 890
+ C+ YEP RPSFR I+RDL L + ++LT N P DPT
Sbjct 784 INNCMDYEPDFRPSFRAIIRDLNSLFTPDY-ELLTENDMLPNMRIGALGFSGAFEDRDPT 842
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L+ +H +++EI+I
Sbjct 843 QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST-EEHLRDFEREIEI 901
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQIC 1008
L++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I +LL + QIC
Sbjct 902 LKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQIC 961
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V+E G+SP+FWY
Sbjct 962 KGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWY 1021
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQGQMTVLRLTEL 1127
APE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG QGQM V L EL
Sbjct 1022 APESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL 1081
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L+ RLPRPD CP E+Y +M CW + RP+F +L
Sbjct 1082 LKNNGRLPRPDGCPDEIYIIMTECWNNNVNQRPSFRDL 1119
Score = 87.8 bits (216), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 95/364 (26%), Positives = 164/364 (45%), Gaps = 62/364 (17%)
Query 837 SCPQLATLTSQCLTYEPTQ----RPSFRTILRDLTRLQPHNLADVLTVNPDSPA------ 886
+C Q+ T+ S + ++ T+ +P ++ +L + + ++DV P SP
Sbjct 479 NCYQMETVRSDSIIFQFTKCCPPKPKDKS---NLLVFRTNGISDV----PTSPTLQRHNN 531
Query 887 SDPTVFHKRYLKKI---RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS- 942
+ VFHK + + LG+G F K+ D G++ + L HR+
Sbjct 532 VNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGD-YGQLHETEVLLKVLDKAHRNY 590
Query 943 --GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLA 998
+ + ++ L H+H++ G C GE+++ LV E+V GSL YL ++ SI +
Sbjct 591 SESFFEAASMMSQLSHKHLVLNYGVCV-CGEENI-LVQEFVKFGSLDTYLKKNKNSINIL 648
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL--DNDR------LVKIGDFGLAKAV-P 1049
L A+Q+ M +L + IH ++ A+N+LL + DR +K+ D G++ V P
Sbjct 649 WKLEVAKQLAWAMHFLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLP 708
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
+ R+ W PEC++ K A+D WSFG TL+E+ C P
Sbjct 709 KDILQERIP--------WVPPECIENPKNLNLATDKWSFGTTLWEI---CSGGDKP---- 753
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
+ R + E +LP P E+ +L+ NC + E FRP+F +I
Sbjct 754 -------LNALDSQRKLQFYEDRHQLPAPKWT--ELANLINNCMDYEPDFRPSFRAIIRD 804
Query 1169 LKTV 1172
L ++
Sbjct 805 LNSL 808
>sp|P52333|JAK3_HUMAN Tyrosine-protein kinase JAK3 OS=Homo sapiens
OX=9606 GN=JAK3 PE=1 SV=2
Length=1124
Score = 684 bits (1766), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 463/1200 (39%), Positives = 630/1200 (53%), Gaps = 150/1200 (13%)
Query 26 GGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWL 85
G L VLL GPG + ++FS AE++C+ A GI P +LFAL W
Sbjct 24 GALHVLLPARGPGPPQ-RLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWF 82
Query 86 PPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLD 145
PP+HI + ++ +L +RIRFYF NW G+ +R G AS+ +LD
Sbjct 83 PPSHIFSVEDASTQVLLYRIRFYFPNWFGLE----KCHRFGLRKDLASA--------ILD 130
Query 146 PASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEV 205
E+LF Q + + V+ + LS +E+ E L +A L L +A E+
Sbjct 131 LPVLEHLFAQHRSDLVSGRLPV-GLSLKEQ-----GECLSLAVLDLARMAREQAQRPGEL 184
Query 206 AKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLER 265
K S+K C+P S R I+ S +TR R+R RR LR + + +M KY+ LER
Sbjct 185 LKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLER 244
Query 266 LAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQ 325
L P E V G P + + V G GGI
Sbjct 245 LDPAGAAETFHV----------GLPGALGGHDG--------------LGLLRVAGDGGIA 280
Query 326 WWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITH 385
W E+EV QP FCDF +I
Sbjct 281 WTQGEQEVL-----------------------------QP-----------FCDFPEIVD 300
Query 386 VVLKE----------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLC 435
+ +K+ V++ R DN+ LE P ALSFV+LVDGYFRLT DS H+ C
Sbjct 301 ISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFC 360
Query 436 HEVAPPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTV-AQRS 491
EVAPPRL+ + + HGP+ F KL+ G Y++ S +LTV Q
Sbjct 361 KEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNP 420
Query 492 QAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCC 551
PD L +R+ P G F+L G R S+REL A L +L CC
Sbjct 421 LGPDYKGCL-IRRSPT----GTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCC 475
Query 552 LPQPGETSNLIIMRGARASPRT--------LNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603
+P+P E SNLI+++ + P + LSQ++FH++ + +LG G+ T +
Sbjct 476 IPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKI 535
Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663
Y G R E +V G R E V+LKV+D H + +F E ASLMS
Sbjct 536 YRG-CRHE---------------VVDGEARKTE--VLLKVMDAKHKNCMESFLEAASLMS 577
Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASAL 722
QVS+ HL +HGVC+ G ++ MV E+V G +D++LR+ RGH VP +WK+ V +QLA AL
Sbjct 578 QVSYRHLVLLHGVCMAG-DSTMVQEFVHLGAIDMYLRK-RGHLVPASWKLQVVKQLAYAL 635
Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPE 782
+YLE+K L HGNV R +LLAR G A+G+ PFIKLSDPGV LS E +RIPW+APE
Sbjct 636 NYLEDKGLPHGNVSARKVLLAREG-ADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPE 694
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLA 842
CL A +LS DKWGFGAT+ E+ P+ + P++K FY+ + +LP P +LA
Sbjct 695 CL-REAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELA 753
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA--------------SD 888
L QC+ YEP QRPSFR ++RDL L + + P + A D
Sbjct 754 LLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQD 813
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
PT+F +R+LK I LG+G+FG V L YDP D TG +VAVK L+ GP + +++EI
Sbjct 814 PTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHS-GPDQQRDFQREI 872
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQ 1006
IL+ L+ + I+KY+G G +SL+LVMEY+P G LRD+L RH L ++LLL++ Q
Sbjct 873 QILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQ 932
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
IC+GM YL ++ +HRDLAARN+L++++ VKI DFGLAK +P +YY VRE G SP+F
Sbjct 933 ICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIF 992
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
WYAPE L + F SDVWSFGV LYEL T+CD S SP +FL ++G + + RL E
Sbjct 993 WYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLE 1052
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
LLE G+RLP P CP EV+ LMK CW RP+F L P L + +G F+
Sbjct 1053 LLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAFTA 1112
>sp|Q62137|JAK3_MOUSE Tyrosine-protein kinase JAK3 OS=Mus musculus
OX=10090 GN=Jak3 PE=1 SV=2
Length=1100
Score = 671 bits (1730), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 448/1166 (38%), Positives = 601/1166 (52%), Gaps = 149/1166 (13%)
Query 44 VTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYF 103
++FS AE++C+ A GI P +LFAL W PP+HI I + +L +
Sbjct 41 LSFSFGDYLAEDLCVRAAKACGILPVYHSLFALATEDFSCWFPPSHIFCIEDVDTQVLVY 100
Query 104 RIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVND 163
R+RFYF +W G+ +R G D T+ +LD E+LF Q + + V+
Sbjct 101 RLRFYFPDWFGLE----TCHRFG-----LRKDLTSA---ILDLHVLEHLFAQHRSDLVSG 148
Query 164 VASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHI 223
+ LS +E+ E L +A L L +A E+ K S+K C+P S R I
Sbjct 149 RLPV-GLSMKEQ-----GEFLSLAVLDLAQMAREQAQRPGELLKTVSYKACLPPSLRDVI 202
Query 224 RQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLL 283
+ + +TR R+R LR + + +M KY+ LERL P TE V L
Sbjct 203 QGQNFVTRRRIRRTVVLALRRVVACQADRYALMAKYILDLERLHPAATTETFRVG----L 258
Query 284 AQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSS 343
A+ EP +R V G GI W SSG
Sbjct 259 PGAQEEPGLLR-----------------------VAGDNGISW------------SSGD- 282
Query 344 GRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKE----------HCV 393
+ L+ FCDF +I V +K+ V
Sbjct 283 ---------------------------QELFQTFCDFPEIVDVSIKQAPRVGPAGEHRLV 315
Query 394 SIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHG 453
++ R D LE P ALSFV+LVDGYFRL DS HY C EVAPPRL+ + HG
Sbjct 316 TVTRMDGHILEAEFPGLPEALSFVALVDGYFRLICDSRHYFCKEVAPPRLLEEEAELCHG 375
Query 454 PLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQ 510
P+ F KL+ G Y++ S +LT ++ + +R+ P
Sbjct 376 PITLDFAIHKLKAAGSLPGTYILRRSPQDYDSFLLTACVQTPLGPDYKGCLIRQDP---- 431
Query 511 DGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMR----- 565
GAF L G + S+REL AA LR +L CC P+P E SNLI++R
Sbjct 432 SGAFSLVGLSQPHRSLRELLAACWNSGLRVDGAALNLTSCCAPRPKEKSNLIVVRRGCTP 491
Query 566 --GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
SP L+QLSFH + + +LG G+ T ++ GR R G+ + +
Sbjct 492 APAPGCSPSCCALTQLSFHTIPTDSLEWHENLGHGSFTKIFRGRRREVVDGETHDSE--- 548
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
V+LKV+D H + +F E ASLMSQVS+ HL +HGVC+ G ++
Sbjct 549 ---------------VLLKVMDSRHRNCMESFLEAASLMSQVSYPHLVLLHGVCMAG-DS 592
Query 684 IMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
IMV E+V G +D++LR+ RGH V +WK+ V +QLA AL+YLE+K L HGNV R +LL
Sbjct 593 IMVQEFVYLGAIDMYLRK-RGHLVSASWKLQVTKQLAYALNYLEDKGLPHGNVSARKVLL 651
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
AR G +G PFIKLSDPGV LS E +RIPW+APECL A +L DKWGFGA
Sbjct 652 AREG-GDGNPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECL-QEAQTLCLEADKWGFGA 709
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
T E+ G A + S P++K FY+ Q +LP +LA L +QC+ Y+P +RPSFR I
Sbjct 710 TTWEVFSGGPAHITSLEPAKKLKFYEDQGQLPALKWTELAGLITQCMAYDPGRRPSFRAI 769
Query 863 LRDLTRLQPHNLADVLTVNPDSPA--------------SDPTVFHKRYLKKIRDLGEGHF 908
LRDL L + + P P+ DP +F +R+LK I LG+G+F
Sbjct 770 LRDLNGLITSDYELLSDPTPGIPSPRDELCGGAQLYACQDPAIFEERHLKYISLLGKGNF 829
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968
G V L YDP D TG +VAVK L+ GP + +++EI IL+ L+ + I+KY+G
Sbjct 830 GSVELCRYDPLGDNTGPLVAVKQLQHS-GPDQQRDFQREIQILKALHSDFIVKYRGVSYG 888
Query 969 QGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
G +SL+LVMEY+P G LRD+L RH L +LLLFA QIC+GM YL A+ +HRDLAA
Sbjct 889 PGRQSLRLVMEYLPSGCLRDFLQRHRARLHTDRLLLFAWQICKGMEYLGARRCVHRDLAA 948
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RN+L++++ VKI DFGLAK +P G +YY VRE G SP+FWYAPE L + F SDVWS
Sbjct 949 RNILVESEAHVKIADFGLAKLLPLGKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWS 1008
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
FGV LYEL T+CD S SP +FL ++G + + RL ELL G RLP P CP EV
Sbjct 1009 FGVVLYELFTYCDKSCSPSAEFLRMMGPEREGPPLCRLLELLAEGRRLPPPPTCPTEVQE 1068
Query 1147 LMKNCWETEASFRPTFENLIPILKTV 1172
LM+ CW RP F L P L +
Sbjct 1069 LMQLCWAPSPHDRPAFGTLSPQLDAL 1094
>sp|Q63272|JAK3_RAT Tyrosine-protein kinase JAK3 OS=Rattus norvegicus
OX=10116 GN=Jak3 PE=2 SV=2
Length=1100
Score = 660 bits (1704), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 439/1166 (38%), Positives = 601/1166 (52%), Gaps = 149/1166 (13%)
Query 44 VTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYF 103
++FS AE++C+ A GI P +LFAL W PP+HI I + +L +
Sbjct 41 LSFSFGDYLAEDLCVRAAKACGILPVYHSLFALATEDLSCWFPPSHIFSIEDVDTQVLVY 100
Query 104 RIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVND 163
R+RFYF W G+ +R G D T+ +LD E+LF Q + + V+
Sbjct 101 RLRFYFPGWFGLE----TCHRFG-----LHKDLTSA---ILDVHVLEHLFAQHRSDLVSG 148
Query 164 VASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHI 223
+ LS +++ E L +A L L +A + E+ K S+K C+P S R I
Sbjct 149 RLPV-GLSLKDQ-----GEFLSLAVLDLAQMARKQAQRPGELLKSVSYKACLPPSLRDLI 202
Query 224 RQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLL 283
+ S +TR R+R + LR + + +M KY+ LERL P TE V L
Sbjct 203 QGQSFVTRRRIRRTVVQALRRVVACQADRYALMAKYILDLERLHPAATTESFLVG----L 258
Query 284 AQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSS 343
A+ EP +R VTG GI W ++E
Sbjct 259 PGAQEEPGCLR-----------------------VTGDNGIAWSSKDQE----------- 284
Query 344 GRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKE----------HCV 393
L+ FCDF +I V +K+ V
Sbjct 285 -----------------------------LFQTFCDFPEIVDVSIKQAPRVGPAGEHRLV 315
Query 394 SIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHG 453
+I R D LE P ALSFV+LVDGYFRL DS H+ C EVAPPRL+ + HG
Sbjct 316 TITRMDGHILEAEFPGLPEALSFVALVDGYFRLICDSRHFFCKEVAPPRLLEEEAELCHG 375
Query 454 PLLEPFVQAKLRPEDGL---YLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQ 510
P+ F KL+ L Y++ S +LT ++ + +R+ P
Sbjct 376 PITLDFAIHKLKAAGSLPGSYILRRSPQDYDSFLLTACVQTPLGPDYKGCLIRQDP---- 431
Query 511 DGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARA- 569
GAF L G + S++EL A L+ +L CC+P+P E SNLI++R R
Sbjct 432 SGAFSLVGLSQLHRSLQELLTACWHSGLQVDGTALNLTSCCVPRPKEKSNLIVVRRGRNP 491
Query 570 ------SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
SP L++LSFH + + +LG G+ T ++ G R G+ + +
Sbjct 492 TPAPGHSPSCCALTKLSFHTIPADSLEWHENLGHGSFTKIFHGHRREVVDGETHDTE--- 548
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
V+LKV+D H + +F E ASLMSQVS+ HL +HGVC+ G ++
Sbjct 549 ---------------VLLKVMDSRHQNCMESFLEAASLMSQVSYPHLVLLHGVCMAG-DS 592
Query 684 IMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
IMV E+V G +D +LR+ RGH VP +WK+ V +QLA AL+YLE+K L HGNV R +LL
Sbjct 593 IMVQEFVYLGAIDTYLRK-RGHLVPASWKLQVTKQLAYALNYLEDKGLPHGNVSARKVLL 651
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
AR G+ +G PFIKLSDPGV LS E +RIPW+APECL A +L+ DKWGFGA
Sbjct 652 AREGV-DGNPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECL-QEAGTLNLEADKWGFGA 709
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
T E+ + S P++K FY+ + +LP +L L +QC+ Y+P +RPSFR I
Sbjct 710 TTWEVFSGAPMHITSLEPAKKLKFYEDRGQLPALKWTELEGLIAQCMAYDPGRRPSFRAI 769
Query 863 LRDLTRLQPHNLADVLTVNPDSP--------------ASDPTVFHKRYLKKIRDLGEGHF 908
LRDL L + + P P DP +F +R+LK I LG+G+F
Sbjct 770 LRDLNGLITSDYELLSDPTPGIPNPRDELCGGAQLYACQDPAIFEERHLKYISLLGKGNF 829
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968
G V L YDP D TG +VAVK L+ GP+ + +++EI IL+ L+ + I+KY+G
Sbjct 830 GSVELCRYDPLGDNTGPLVAVKQLQHS-GPEQQRDFQREIQILKALHCDFIVKYRGVSYG 888
Query 969 QGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
G +SL+LVMEY+P G LRD+L RH L +LLLFA QIC+GM YL A+ +HRDLAA
Sbjct 889 PGRQSLRLVMEYLPSGCLRDFLQRHRARLHNDRLLLFAWQICKGMEYLGARRCVHRDLAA 948
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RN+L++++ VKI DFGLAK +P G +YY VRE G SP+FWYAPE L + F SDVWS
Sbjct 949 RNILVESEAHVKIADFGLAKLLPLGKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWS 1008
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
FGV LYEL T+ D S SP T+FL ++G + + L ELL G RLP P CP EV
Sbjct 1009 FGVVLYELFTYSDKSCSPSTEFLRMMGPEREGSPLCHLLELLAEGRRLPPPSTCPTEVQE 1068
Query 1147 LMKNCWETEASFRPTFENLIPILKTV 1172
LM+ CW RP F+ L P L +
Sbjct 1069 LMQLCWSPNPQDRPAFDTLSPQLDAL 1094
>sp|O54967|ACK1_MOUSE Activated CDC42 kinase 1 OS=Mus musculus
OX=10090 GN=Tnk2 PE=1 SV=2
Length=1055
Score = 182 bits (461), Expect = 3e-45, Method: Compositional matrix adjust.
Identities = 109/279 (39%), Positives = 158/279 (57%), Gaps = 21/279 (8%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEI 948
+ ++ L+ + LG+G FG V +D G VAVK LK D P+ + +E+
Sbjct 120 LIGEKDLRLLEKLGDGSFGVVRRGEWD-APAGKTVSVAVKCLKPDVLSQPEAMDDFIREV 178
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006
+ + +L H ++I+ G +++V E PLGSL D L +H L L +A Q
Sbjct 179 NAMHSLDHRNLIRLYGVVL---TLPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQ 235
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+ EGMAYL ++ +IHRDLAARN+LL LVKIGDFGL +A+P+ ++Y ++E P
Sbjct 236 VAEGMAYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFA 295
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE LK F +ASD W FGVTL+E+ T+ Q P IG+ Q+ L +
Sbjct 296 WCAPESLKTRTFSHASDTWMFGVTLWEMFTY---GQEP------WIGLNGSQI----LHK 342
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + GERLPRP+ CP ++Y++M CW + RPTF L
Sbjct 343 IDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVAL 381
Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 78/255 (31%), Positives = 119/255 (47%), Gaps = 25/255 (10%)
Query 634 GQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
G+ + V +K L P S + F + M + H +L ++GV + P MVTE
Sbjct 150 GKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTLPMK-MVTELA 208
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L LR+ +GH + A Q+A ++YLE+K +H ++ RN+LLA
Sbjct 209 PLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMAYLESKRFIHRDLAARNLLLA------- 261
Query 751 TSPFIKLSDPGVGLGALS--------REERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
T +K+ D G+ + AL +E R W APE L + S A D W FG
Sbjct 262 TRDLVKIGDFGL-MRALPQNDDHYVMQEHRKVPFAWCAPESL--KTRTFSHASDTWMFGV 318
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEP-SCPQ-LATLTSQCLTYEPTQRPSF 859
TL E+ G+ P + S+ H ++ RLP P CPQ + + QC ++P RP+F
Sbjct 319 TLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTF 378
Query 860 RTILRDLTRLQPHNL 874
+ L QP ++
Sbjct 379 VALRDFLLEAQPTDM 393
>sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens
OX=9606 GN=TNK2 PE=1 SV=3
Length=1038
Score = 181 bits (458), Expect = 5e-45, Method: Compositional matrix adjust.
Identities = 108/279 (39%), Positives = 157/279 (56%), Gaps = 21/279 (8%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEI 948
+ ++ L+ + LG+G FG V +D G VAVK LK D P+ + +E+
Sbjct 120 LIGEKDLRLLEKLGDGSFGVVRRGEWD-APSGKTVSVAVKCLKPDVLSQPEAMDDFIREV 178
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006
+ + +L H ++I+ G +++V E PLGSL D L +H L L +A Q
Sbjct 179 NAMHSLDHRNLIRLYGVVL---TPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQ 235
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+ EGM YL ++ +IHRDLAARN+LL LVKIGDFGL +A+P+ ++Y ++E P
Sbjct 236 VAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFA 295
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE LK F +ASD W FGVTL+E+ T+ Q P IG+ Q+ L +
Sbjct 296 WCAPESLKTRTFSHASDTWMFGVTLWEMFTY---GQEP------WIGLNGSQI----LHK 342
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + GERLPRP+ CP ++Y++M CW + RPTF L
Sbjct 343 IDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVAL 381
Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 78/255 (31%), Positives = 118/255 (46%), Gaps = 25/255 (10%)
Query 634 GQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
G+ + V +K L P S + F + M + H +L ++GV + P MVTE
Sbjct 150 GKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMK-MVTELA 208
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L LR+ +GH + A Q+A + YLE+K +H ++ RN+LLA
Sbjct 209 PLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLA------- 261
Query 751 TSPFIKLSDPGVGLGALS--------REERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
T +K+ D G+ + AL +E R W APE L + S A D W FG
Sbjct 262 TRDLVKIGDFGL-MRALPQNDDHYVMQEHRKVPFAWCAPESL--KTRTFSHASDTWMFGV 318
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEP-SCPQ-LATLTSQCLTYEPTQRPSF 859
TL E+ G+ P + S+ H ++ RLP P CPQ + + QC ++P RP+F
Sbjct 319 TLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTF 378
Query 860 RTILRDLTRLQPHNL 874
+ L QP ++
Sbjct 379 VALRDFLLEAQPTDM 393
>sp|Q17R13|ACK1_BOVIN Activated CDC42 kinase 1 OS=Bos taurus OX=9913
GN=TNK2 PE=1 SV=1
Length=1039
Score = 179 bits (454), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 109/279 (39%), Positives = 154/279 (55%), Gaps = 21/279 (8%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEI 948
+ ++ L LG+G FG V +D G VAVK LK D P+ + +E+
Sbjct 120 LIGEKDLHLFEKLGDGSFGVVRRGEWD-APSGKTVSVAVKCLKPDVLSQPEAMDDFIREV 178
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006
+ + +L H ++I+ G ++ V E PLGSL D L +H L L +A Q
Sbjct 179 NAMHSLDHRNLIRLYGVVL---TPPMKTVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQ 235
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+ EGM YL A+ +IHRDLAARN+LL LVKIGDFGL +A+P+ ++Y ++E P
Sbjct 236 VAEGMGYLEAKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFA 295
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE LK F +ASD W FGVTL+E+ T+ Q P IG+ Q+ L +
Sbjct 296 WCAPESLKTRTFSHASDTWMFGVTLWEMFTY---GQEP------WIGLNGSQI----LHK 342
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + GERLPRP+ CP ++Y++M CW + RPTF L
Sbjct 343 IDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVAL 381
Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 77/255 (30%), Positives = 116/255 (45%), Gaps = 25/255 (10%)
Query 634 GQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
G+ + V +K L P S + F + M + H +L ++GV + P VTE
Sbjct 150 GKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKT-VTELA 208
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L LR+ +GH + A Q+A + YLE K +H ++ RN+LLA
Sbjct 209 PLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLEAKRFIHRDLAARNLLLA------- 261
Query 751 TSPFIKLSDPGVGLGALS--------REERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
T +K+ D G+ + AL +E R W APE L + S A D W FG
Sbjct 262 TRDLVKIGDFGL-MRALPQNDDHYVMQEHRKVPFAWCAPESL--KTRTFSHASDTWMFGV 318
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEP-SCPQ-LATLTSQCLTYEPTQRPSF 859
TL E+ G+ P + S+ H ++ RLP P CPQ + + QC ++P RP+F
Sbjct 319 TLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTF 378
Query 860 RTILRDLTRLQPHNL 874
+ L QP ++
Sbjct 379 VALRDFLLEAQPTDM 393
>sp|Q5U2X5|ACK1_RAT Activated CDC42 kinase 1 OS=Rattus norvegicus
OX=10116 GN=Tnk2 PE=2 SV=1
Length=1040
Score = 179 bits (454), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 108/279 (39%), Positives = 156/279 (56%), Gaps = 21/279 (8%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEI 948
+ ++ L+ + LG+G FG V +D G VAVK LK D P+ + +E+
Sbjct 120 LIGEKDLRLLEKLGDGSFGVVRRGEWD-APAGKTVSVAVKCLKPDVLSQPEAMDDFIREV 178
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006
+ + +L H ++I+ G +++V E PLGSL D L +H L L +A Q
Sbjct 179 NAMHSLDHRNLIRLYGVVL---TPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQ 235
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+ EGM YL ++ +IHRDLAARN+LL LVKIGDFGL +A+P+ +Y ++E P
Sbjct 236 VAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDGHYVMQEHRKVPFA 295
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE LK F +ASD W FGVTL+E+ T+ Q P IG+ Q+ L +
Sbjct 296 WCAPESLKTRTFSHASDTWMFGVTLWEMFTY---GQEP------WIGLNGSQI----LHK 342
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + GERLPRP+ CP ++Y++M CW + RPTF L
Sbjct 343 IDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVAL 381
Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 78/255 (31%), Positives = 118/255 (46%), Gaps = 25/255 (10%)
Query 634 GQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
G+ + V +K L P S + F + M + H +L ++GV + P MVTE
Sbjct 150 GKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMK-MVTELA 208
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L LR+ +GH + A Q+A + YLE+K +H ++ RN+LLA
Sbjct 209 PLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLA------- 261
Query 751 TSPFIKLSDPGVGLGALS--------REERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
T +K+ D G+ + AL +E R W APE L + S A D W FG
Sbjct 262 TRDLVKIGDFGL-MRALPQNDGHYVMQEHRKVPFAWCAPESL--KTRTFSHASDTWMFGV 318
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEP-SCPQ-LATLTSQCLTYEPTQRPSF 859
TL E+ G+ P + S+ H ++ RLP P CPQ + + QC ++P RP+F
Sbjct 319 TLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTF 378
Query 860 RTILRDLTRLQPHNL 874
+ L QP ++
Sbjct 379 VALRDFLLEAQPTDM 393
>sp|P24786|NTRK3_PIG NT-3 growth factor receptor OS=Sus scrofa
OX=9823 GN=NTRK3 PE=2 SV=1
Length=825
Score = 177 bits (450), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 111/287 (39%), Positives = 152/287 (53%), Gaps = 36/287 (13%)
Query 901 RDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
R+LGEG FGKV L CY+ + +VAVKALK D R +++E ++L L HEHI
Sbjct 542 RELGEGAFGKVFLAECYNLSPTKVKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHI 600
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLL 1002
+K+ G C D L +V EY+ G L +L H +GL+Q+L
Sbjct 601 VKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLH 658
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
A QIC GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV
Sbjct 659 IASQICSGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDV-YSTDYYRVGGHTM 717
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
P+ W PE + KF SDVWSFGV L+E+ T+ + P Q++
Sbjct 718 LPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY---GKQP-----------WFQLSNT 763
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ E + +G L RP CP EVY +M CW+ E R + + IL
Sbjct 764 EVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810
Score = 78.2 bits (191), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 63/238 (26%), Positives = 105/238 (44%), Gaps = 32/238 (13%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL--------------- 699
F A L++ + H H+ +GVC G IMV EY++HG L+ +L
Sbjct 585 FQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQP 644
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R+ +G + ++ + +A Q+ S + YL +++ VH ++ RN L+ G + +K+ D
Sbjct 645 RQAKGELGLSQMLHIASQICSGMVYLASQHFVHRDLATRNCLV-------GANLLVKIGD 697
Query 760 PGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ S + + I W+ PE + +T D W FG L EI G+
Sbjct 698 FGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGVILWEIFTYGKQ 755
Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
P S +E + L P CP ++ + C EP QR + + I + L L
Sbjct 756 PWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813
>sp|Q91044|NTRK3_CHICK NT-3 growth factor receptor OS=Gallus gallus
OX=9031 GN=NTRK3 PE=1 SV=2
Length=827
Score = 177 bits (448), Expect = 4e-44, Method: Compositional matrix adjust.
Identities = 114/289 (39%), Positives = 154/289 (53%), Gaps = 40/289 (14%)
Query 901 RDLGEGHFGKVSLY-CYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
R+LGEG FGKV L CY+ PTND +VAVKALK D R +++E ++L L HE
Sbjct 544 RELGEGAFGKVFLAECYNLSPTNDKM--LVAVKALK-DPTLAARKDFQREAELLTNLQHE 600
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQL 1000
HI+K+ G C D L +V EY+ G L +L H +GL+Q+
Sbjct 601 HIVKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQM 658
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
L A QI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV
Sbjct 659 LHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDV-YSTDYYRVGGH 717
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
P+ W PE + KF SDVWSFGV L+E+ T+ + P Q++
Sbjct 718 TMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY---GKQP-----------WFQLS 763
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ E + +G L RP CP EVY +M CW+ E R + + IL
Sbjct 764 NTEVIECITQGRVLERPRVCPKEVYDIMLGCWQREPQQRLNIKEIYKIL 812
Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 64/238 (27%), Positives = 106/238 (45%), Gaps = 32/238 (13%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL--------------- 699
F A L++ + H H+ +GVC G IMV EY++HG L+ +L
Sbjct 587 FQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQP 646
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R+ +G + ++ + +A Q+AS + YL +++ VH ++ RN L+ G + +K+ D
Sbjct 647 RQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV-------GANLLVKIGD 699
Query 760 PGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ S + + I W+ PE + +T D W FG L EI G+
Sbjct 700 FGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGVILWEIFTYGKQ 757
Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
P S +E + L P CP ++ + C EP QR + + I + L L
Sbjct 758 PWFQLSNTEVIECITQGRVLERPRVCPKEVYDIMLGCWQREPQQRLNIKEIYKILHAL 815
>sp|Q5IS37|NTRK3_PANTR NT-3 growth factor receptor OS=Pan troglodytes
OX=9598 GN=NTRK3 PE=2 SV=1
Length=825
Score = 174 bits (441), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 113/289 (39%), Positives = 153/289 (53%), Gaps = 40/289 (14%)
Query 901 RDLGEGHFGKVSLY-CYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
R+LGEG FGKV L CY+ PT D +VAVKALK D R +++E ++L L HE
Sbjct 542 RELGEGAFGKVFLAECYNLSPTKDKM--LVAVKALK-DPTLAARKDFQREAELLTNLQHE 598
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQL 1000
HI+K+ G C D L +V EY+ G L +L H +GL+Q+
Sbjct 599 HIVKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQM 656
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
L A QI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV
Sbjct 657 LHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDV-YSTDYYRVGGH 715
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
P+ W PE + KF SDVWSFGV L+E+ T+ + P Q++
Sbjct 716 TMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY---GKQP-----------WFQLS 761
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ E + +G L RP CP EVY +M CW+ E R + + IL
Sbjct 762 NTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810
Score = 80.9 bits (198), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 70/266 (26%), Positives = 116/266 (44%), Gaps = 35/266 (13%)
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
L P +D+ + V +K L F A L++ + H H+ +GVC G IMV
Sbjct 560 LSPTKDK---MLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMV 616
Query 687 TEYVEHGPLDVWL---------------RRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
EY++HG L+ +L R+ +G + ++ + +A Q+AS + YL +++ V
Sbjct 617 FEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFV 676
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785
H ++ RN L+ G + +K+ D G+ S + + I W+ PE +
Sbjct 677 HRDLATRNCLV-------GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESI- 728
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLAT 843
+T D W FG L EI G+ P S +E + L P CP ++
Sbjct 729 -MYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYD 787
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869
+ C EP QR + + I + L L
Sbjct 788 VMLGCWQREPQQRLNIKEIYKILHAL 813
>sp|Q5IFJ9|NTRK3_MACFA NT-3 growth factor receptor OS=Macaca fascicularis
OX=9541 GN=NTRK3 PE=2 SV=1
Length=825
Score = 174 bits (441), Expect = 3e-43, Method: Compositional matrix adjust.
Identities = 113/289 (39%), Positives = 153/289 (53%), Gaps = 40/289 (14%)
Query 901 RDLGEGHFGKVSLY-CYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
R+LGEG FGKV L CY+ PT D +VAVKALK D R +++E ++L L HE
Sbjct 542 RELGEGAFGKVFLAECYNLSPTKDKM--LVAVKALK-DPTLAARKDFQREAELLTNLQHE 598
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQL 1000
HI+K+ G C D L +V EY+ G L +L H +GL+Q+
Sbjct 599 HIVKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQM 656
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
L A QI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV
Sbjct 657 LHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDV-YSTDYYRVGGH 715
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
P+ W PE + KF SDVWSFGV L+E+ T+ + P Q++
Sbjct 716 TMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY---GKQP-----------WFQLS 761
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ E + +G L RP CP EVY +M CW+ E R + + IL
Sbjct 762 NTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810
Score = 80.9 bits (198), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 70/266 (26%), Positives = 116/266 (44%), Gaps = 35/266 (13%)
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
L P +D+ + V +K L F A L++ + H H+ +GVC G IMV
Sbjct 560 LSPTKDK---MLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMV 616
Query 687 TEYVEHGPLDVWL---------------RRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
EY++HG L+ +L R+ +G + ++ + +A Q+AS + YL +++ V
Sbjct 617 FEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFV 676
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785
H ++ RN L+ G + +K+ D G+ S + + I W+ PE +
Sbjct 677 HRDLATRNCLV-------GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM 729
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLAT 843
+T D W FG L EI G+ P S +E + L P CP ++
Sbjct 730 --YRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYD 787
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869
+ C EP QR + + I + L L
Sbjct 788 VMLGCWQREPQQRLNIKEIYKILHAL 813
>sp|Q6VNS1|NTRK3_MOUSE NT-3 growth factor receptor OS=Mus musculus
OX=10090 GN=Ntrk3 PE=1 SV=1
Length=825
Score = 174 bits (440), Expect = 3e-43, Method: Compositional matrix adjust.
Identities = 113/289 (39%), Positives = 153/289 (53%), Gaps = 40/289 (14%)
Query 901 RDLGEGHFGKVSLY-CYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
R+LGEG FGKV L CY+ PT D +VAVKALK D R +++E ++L L HE
Sbjct 542 RELGEGAFGKVFLAECYNLSPTKDKM--LVAVKALK-DPTLAARKDFQREAELLTNLQHE 598
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQL 1000
HI+K+ G C D L +V EY+ G L +L H +GL+Q+
Sbjct 599 HIVKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQM 656
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
L A QI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV
Sbjct 657 LHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDV-YSTDYYRVGGH 715
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
P+ W PE + KF SDVWSFGV L+E+ T+ + P Q++
Sbjct 716 TMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY---GKQP-----------WFQLS 761
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ E + +G L RP CP EVY +M CW+ E R + + IL
Sbjct 762 NTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810
Score = 80.9 bits (198), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 70/266 (26%), Positives = 116/266 (44%), Gaps = 35/266 (13%)
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
L P +D+ + V +K L F A L++ + H H+ +GVC G IMV
Sbjct 560 LSPTKDK---MLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMV 616
Query 687 TEYVEHGPLDVWL---------------RRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
EY++HG L+ +L R+ +G + ++ + +A Q+AS + YL +++ V
Sbjct 617 FEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFV 676
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785
H ++ RN L+ G + +K+ D G+ S + + I W+ PE +
Sbjct 677 HRDLATRNCLV-------GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM 729
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLAT 843
+T D W FG L EI G+ P S +E + L P CP ++
Sbjct 730 --YRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYD 787
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869
+ C EP QR + + I + L L
Sbjct 788 VMLGCWQREPQQRLNIKEIYKILHAL 813
>sp|Q3UFB7|NTRK1_MOUSE High affinity nerve growth factor receptor
OS=Mus musculus OX=10090 GN=Ntrk1 PE=1 SV=2
Length=799
Score = 173 bits (438), Expect = 5e-43, Method: Compositional matrix adjust.
Identities = 113/316 (36%), Positives = 159/316 (50%), Gaps = 46/316 (15%)
Query 887 SDPTVFHKRYLKKIR--DLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSG 943
SD V H + I +LGEG FGKV L CY+ ND +VAVKALK + R
Sbjct 501 SDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALK-EASENARQD 559
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------- 994
+++E ++L L H+HI+++ G C + G L +V EY+ G L +L H
Sbjct 560 FQREAELLTMLQHQHIVRFFGVCTEGG--PLLMVFEYMRHGDLNRFLRSHGPDAKLLAGG 617
Query 995 -------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
+GL QLL A Q+ GM YL + H++HRDLA RN L+ +VKIGDFG+++
Sbjct 618 EDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRD 677
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ +YYRV P+ W PE + KF SDVWSFGV L+E+ T+
Sbjct 678 I-YSTDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYGKQPWY---- 732
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
Q++ E + +G L RP CP +VY +M+ CW+ E R +
Sbjct 733 ----------QLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLS------ 776
Query 1168 ILKTVHEKYQ--GQAP 1181
+K VH + Q QAP
Sbjct 777 -MKDVHARLQALAQAP 791
Score = 80.5 bits (197), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 80/327 (24%), Positives = 129/327 (39%), Gaps = 52/327 (16%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
S H + +++I LG+G V+ ++D+D ++
Sbjct 500 FSDTCVHHIKRQDIILKWELGEGAFGKVFLAECY---------NLLNDQDKML------- 543
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K L + + F A L++ + H H+ GVC G +MV EY+ HG L
Sbjct 544 ---VAVKALKEASENARQDFQREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDL 600
Query 696 DVWLRRER--------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
+ +LR G + + + VA Q+A+ + YL + + VH ++ RN L
Sbjct 601 NRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCL 660
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAM 795
+ G +K+ D G+ S + + I W+ PE + ST
Sbjct 661 V-------GQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESIL--YRKFSTES 711
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEP 853
D W FG L EI G+ P S +E + L P +C P + + C EP
Sbjct 712 DVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREP 771
Query 854 TQRPSFRTILRDLTRL--QPHNLADVL 878
QR S + + L L P + DVL
Sbjct 772 QQRLSMKDVHARLQALAQAPPSYLDVL 798
>sp|Q5IS82|NTRK3_SAIBB NT-3 growth factor receptor OS=Saimiri
boliviensis boliviensis OX=39432 GN=NTRK3 PE=2 SV=1
Length=825
Score = 172 bits (436), Expect = 1e-42, Method: Compositional matrix adjust.
Identities = 112/289 (39%), Positives = 152/289 (53%), Gaps = 40/289 (14%)
Query 901 RDLGEGHFGKVSLY-CYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
R+LGEG FGKV L CY+ PT D +VAVKALK D R +++E ++L L HE
Sbjct 542 RELGEGAFGKVFLAECYNLSPTKDKM--LVAVKALK-DPTLAARKDFQREAELLTNLQHE 598
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQL 1000
HI+K+ G C D L +V EY+ G L +L H +GL+Q+
Sbjct 599 HIVKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPXQAKGELGLSQM 656
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
L A QI GM YL +QH++HRDLA RN + + LVKIGDFG+++ V +YYRV
Sbjct 657 LHIASQIASGMVYLASQHFVHRDLATRNCXVGANLLVKIGDFGMSRDV-YSTDYYRVGGH 715
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
P+ W PE + KF SDVWSFGV L+E+ T+ + P Q++
Sbjct 716 TMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY---GKQP-----------WFQLS 761
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ E + +G L RP CP EVY +M CW+ E R + + IL
Sbjct 762 NTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810
Score = 78.6 bits (192), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 69/266 (26%), Positives = 115/266 (43%), Gaps = 35/266 (13%)
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
L P +D+ + V +K L F A L++ + H H+ +GVC G IMV
Sbjct 560 LSPTKDK---MLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMV 616
Query 687 TEYVEHGPLDVWLR---------------RERGHVPMAWKMVVAQQLASALSYLENKNLV 731
EY++HG L+ +LR + +G + ++ + +A Q+AS + YL +++ V
Sbjct 617 FEYMKHGDLNKFLRAHGPDAMILVDGQPXQAKGELGLSQMLHIASQIASGMVYLASQHFV 676
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785
H ++ RN + G + +K+ D G+ S + + I W+ PE +
Sbjct 677 HRDLATRNCXV-------GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESI- 728
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLAT 843
+T D W FG L EI G+ P S +E + L P CP ++
Sbjct 729 -MYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYD 787
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869
+ C EP QR + + I + L L
Sbjct 788 VMLGCWQREPQQRLNIKEIYKILHAL 813
>sp|P35739|NTRK1_RAT High affinity nerve growth factor receptor
OS=Rattus norvegicus OX=10116 GN=Ntrk1 PE=1 SV=1
Length=799
Score = 171 bits (434), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 114/316 (36%), Positives = 160/316 (51%), Gaps = 46/316 (15%)
Query 887 SDPTVFHKRYLKKIR--DLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSG 943
SD V H + I +LGEG FGKV L CY+ ND +VAVKALK + R
Sbjct 501 SDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALK-ETSENARQD 559
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------- 994
+ +E ++L L H+HI+++ G C + G L +V EY+ G L +L H
Sbjct 560 FHREAELLTMLQHQHIVRFFGVCTEGG--PLLMVFEYMRHGDLNRFLRSHGPDAKLLAGG 617
Query 995 -------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
+GL QLL A Q+ GM YL + H++HRDLA RN L+ +VKIGDFG+++
Sbjct 618 EDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRD 677
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ +YYRV P+ W PE + KF SDVWSFGV L+E+ T+ + P
Sbjct 678 I-YSTDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTY---GKQPWY- 732
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
Q++ E + +G L RP CP +VY +M+ CW+ E R +
Sbjct 733 ----------QLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLS------ 776
Query 1168 ILKTVHEKYQ--GQAP 1181
+K VH + Q QAP
Sbjct 777 -MKDVHARLQALAQAP 791
Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 80/327 (24%), Positives = 130/327 (40%), Gaps = 52/327 (16%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
S H + +++I LG+G V+ ++D+D ++
Sbjct 500 FSDTCVHHIKRQDIILKWELGEGAFGKVFLAECY---------NLLNDQDKML------- 543
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K L + + F+ A L++ + H H+ GVC G +MV EY+ HG L
Sbjct 544 ---VAVKALKETSENARQDFHREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDL 600
Query 696 DVWLRRER--------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
+ +LR G + + + VA Q+A+ + YL + + VH ++ RN L
Sbjct 601 NRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCL 660
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAM 795
+ G +K+ D G+ S + + I W+ PE + ST
Sbjct 661 V-------GQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESIL--YRKFSTES 711
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEP 853
D W FG L EI G+ P S +E + L P +C P + + C EP
Sbjct 712 DVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREP 771
Query 854 TQRPSFRTILRDLTRL--QPHNLADVL 878
QR S + + L L P + DVL
Sbjct 772 QQRLSMKDVHARLQALAQAPPSYLDVL 798
>sp|Q63604|NTRK2_RAT BDNF/NT-3 growth factors receptor OS=Rattus
norvegicus OX=10116 GN=Ntrk2 PE=1 SV=1
Length=821
Score = 171 bits (433), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 110/295 (37%), Positives = 153/295 (52%), Gaps = 35/295 (12%)
Query 893 HKRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
H LK R+LGEG FGKV L CY+ + +VAVK LK D R + +E ++L
Sbjct 535 HNIVLK--RELGEGAFGKVFLAECYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELL 591
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------------IGL 997
L HEHI+K+ G C + L +V EY+ G L +L H +
Sbjct 592 TNLQHEHIVKFYGVCVEG--DPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 649
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+Q+L AQQI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV
Sbjct 650 SQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV-YSTDYYRV 708
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
P+ W PE + KF SDVWS GV L+E+ T+ + P
Sbjct 709 GGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTY---GKQP-----------WY 754
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
Q++ + E + +G L RP CP EVY LM CW+ E R +N+ +L+ +
Sbjct 755 QLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHTRKNIKNIHTLLQNL 809
Score = 87.4 bits (215), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 75/271 (28%), Positives = 121/271 (45%), Gaps = 41/271 (15%)
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
L P +D+ + V +K L + + F+ A L++ + H H+ +GVCV G IMV
Sbjct 559 LCPEQDK---ILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMV 615
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMV---------------VAQQLASALSYLENKNLV 731
EY++HG L+ +L R H P A M +AQQ+A+ + YL +++ V
Sbjct 616 FEYMKHGDLNKFL---RAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFV 672
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785
H ++ RN L+ G + +K+ D G+ S + + I W+ PE +
Sbjct 673 HRDLATRNCLV-------GENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESI- 724
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LAT 843
+T D W G L EI G+ P S +E + L P +CPQ +
Sbjct 725 -MYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYE 783
Query 844 LTSQCLTYEPTQRPSFR---TILRDLTRLQP 871
L C EP R + + T+L++L + P
Sbjct 784 LMLGCWQREPHTRKNIKNIHTLLQNLAKASP 814
>sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens
OX=9606 GN=LYN PE=1 SV=3
Length=512
Score = 164 bits (416), Expect = 9e-42, Method: Compositional matrix adjust.
Identities = 101/286 (35%), Positives = 152/286 (53%), Gaps = 28/286 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+K ++ LG G FG+V + Y N+ T VAVK LK G + +E ++++TL H
Sbjct 247 IKLVKRLGAGQFGEVWMGYY---NNSTK--VAVKTLKP--GTMSVQAFLEEANLMKTLQH 299
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAY 1013
+ +++ E+ + ++ EY+ GSL D+L G L +L+ F+ QI EGMAY
Sbjct 300 DKLVRLYAVV--TREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAY 357
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ ++YIHRDL A NVL+ + KI DFGLA+ + + Y RE P+ W APE +
Sbjct 358 IERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAI 415
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
F SDVWSFG+ LYE++T+ I T + L +G R
Sbjct 416 NFGCFTIKSDVWSFGILLYEIVTYGK--------------IPYPGRTNADVMTALSQGYR 461
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+PR + CP E+Y +MK CW+ +A RPTF+ L +L + +GQ
Sbjct 462 MPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQ 507
Score = 87.0 bits (214), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 64/241 (27%), Positives = 115/241 (48%), Gaps = 23/241 (10%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P + AF E A+LM + H L ++ V R ++TEY+ G L
Sbjct 271 KVAVKTLKPGTMSVQ-AFLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLD 329
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ + G + K++ + Q+A ++Y+E KN +H ++ N+L++ S K
Sbjct 330 FLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSE-------SLMCK 382
Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
++D G+ + E R I W APE + G ++ + D W FG L EI
Sbjct 383 IADFGLAR-VIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKS--DVWSFGILLYEIVTY 439
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSF---RTILRD 865
G+ P R+ ++ + +R+P +CP +L + C + +RP+F +++L D
Sbjct 440 GKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDD 499
Query 866 L 866
Sbjct 500 F 500
>sp|Q16620|NTRK2_HUMAN BDNF/NT-3 growth factors receptor OS=Homo
sapiens OX=9606 GN=NTRK2 PE=1 SV=1
Length=822
Score = 169 bits (428), Expect = 9e-42, Method: Compositional matrix adjust.
Identities = 109/295 (37%), Positives = 152/295 (52%), Gaps = 35/295 (12%)
Query 893 HKRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
H LK R+LGEG FGKV L CY+ + +VAVK LK D R + +E ++L
Sbjct 536 HNIVLK--RELGEGAFGKVFLAECYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELL 592
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------------IGL 997
L HEHI+K+ G C + L +V EY+ G L +L H +
Sbjct 593 TNLQHEHIVKFYGVCVEG--DPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 650
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+Q+L AQQI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV
Sbjct 651 SQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV-YSTDYYRV 709
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
P+ W PE + KF SDVWS GV L+E+ T+ + P
Sbjct 710 GGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTY---GKQP-----------WY 755
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
Q++ + E + +G L RP CP EVY LM CW+ E R + + +L+ +
Sbjct 756 QLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQNL 810
Score = 87.8 bits (216), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 75/271 (28%), Positives = 121/271 (45%), Gaps = 41/271 (15%)
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
L P +D+ + V +K L + + F+ A L++ + H H+ +GVCV G IMV
Sbjct 560 LCPEQDK---ILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMV 616
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMV---------------VAQQLASALSYLENKNLV 731
EY++HG L+ +L R H P A M +AQQ+A+ + YL +++ V
Sbjct 617 FEYMKHGDLNKFL---RAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFV 673
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785
H ++ RN L+ G + +K+ D G+ S + + I W+ PE +
Sbjct 674 HRDLATRNCLV-------GENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESI- 725
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LAT 843
+T D W G L EI G+ P S +E + L P +CPQ +
Sbjct 726 -MYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYE 784
Query 844 LTSQCLTYEPTQRPSFR---TILRDLTRLQP 871
L C EP R + + T+L++L + P
Sbjct 785 LMLGCWQREPHMRKNIKGIHTLLQNLAKASP 815
>sp|F1N9Y5|KSYK_CHICK Tyrosine-protein kinase SYK OS=Gallus gallus
OX=9031 GN=SYK PE=1 SV=2
Length=613
Score = 166 bits (421), Expect = 9e-42, Method: Compositional matrix adjust.
Identities = 103/290 (36%), Positives = 149/290 (51%), Gaps = 29/290 (10%)
Query 883 DSPASDPTVFHKRYLKKIR--------DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+SP +DP + + R +LG G+FG V Y + VAVK LK
Sbjct 327 ESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGA--KPVAVKILKN 384
Query 935 DCG-PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993
+ P + +E ++++ L + +I++ G CE + + LVME LG L +L ++
Sbjct 385 ESNDPAIKDELLREANVMQQLDNPYIVRMIGICEAE---AWMLVMEMAELGPLNKFLQKN 441
Query 994 S-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
+ + Q+ GM YL +++HRDLAARNVLL KI DFGL+KA+
Sbjct 442 RHVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLVTQHYAKISDFGLSKALSADE 501
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
YY+ + G PV WYAPEC+ YKF SDVWSFGV ++E ++ Q P
Sbjct 502 NYYKAQSHGKWPVKWYAPECMNFYKFSSKSDVWSFGVLMWEAFSY---GQKP------YK 552
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
G+ G+ + +++ERGER+ P+ CP EVY LMK CW RP F
Sbjct 553 GMKGGE-----VAQMIERGERMECPEACPVEVYDLMKLCWTYNVDDRPGF 597
Score = 89.4 bits (220), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 66/236 (28%), Positives = 108/236 (46%), Gaps = 24/236 (10%)
Query 639 VVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K+L +D A+ A++M Q+ + ++ + G+C ++V E E GPL+
Sbjct 377 VAVKILKNESNDPAIKDELLREANVMQQLDNPYIVRMIGIC-EAEAWMLVMEMAELGPLN 435
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L++ R HV + Q++ + YLE N VH ++ RN+LL T + K
Sbjct 436 KFLQKNR-HVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLV-------TQHYAK 487
Query 757 LSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+SD G+ ALS +E + + W APEC+ S+ D W FG + E
Sbjct 488 ISDFGLS-KALSADENYYKAQSHGKWPVKWYAPECM--NFYKFSSKSDVWSFGVLMWEAF 544
Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTI 862
G+ P + E +R R+ P +CP ++ L C TY RP F +
Sbjct 545 SYGQKPYKGMKGGEVAQMIERGERMECPEACPVEVYDLMKLCWTYNVDDRPGFVAV 600
>sp|P15209|NTRK2_MOUSE BDNF/NT-3 growth factors receptor OS=Mus
musculus OX=10090 GN=Ntrk2 PE=1 SV=1
Length=821
Score = 169 bits (428), Expect = 9e-42, Method: Compositional matrix adjust.
Identities = 109/295 (37%), Positives = 153/295 (52%), Gaps = 35/295 (12%)
Query 893 HKRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
H LK R+LGEG FGKV L CY+ + +VAVK LK D R + +E ++L
Sbjct 535 HNIVLK--RELGEGAFGKVFLAECYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELL 591
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------------IGL 997
L HEHI+K+ G C + L +V EY+ G L +L H +
Sbjct 592 TNLQHEHIVKFYGVCVEG--DPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 649
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+Q+L AQQI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV
Sbjct 650 SQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV-YSTDYYRV 708
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
P+ W PE + KF SDVWS GV L+E+ T+ + P
Sbjct 709 GGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTY---GKQP-----------WY 754
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
Q++ + E + +G L RP CP EVY LM CW+ E R +++ +L+ +
Sbjct 755 QLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHTRKNIKSIHTLLQNL 809
Score = 87.4 bits (215), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 76/271 (28%), Positives = 120/271 (44%), Gaps = 41/271 (15%)
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
L P +D+ + V +K L + + F+ A L++ + H H+ +GVCV G IMV
Sbjct 559 LCPEQDK---ILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMV 615
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMV---------------VAQQLASALSYLENKNLV 731
EY++HG L+ +L R H P A M +AQQ+A+ + YL +++ V
Sbjct 616 FEYMKHGDLNKFL---RAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFV 672
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785
H ++ RN L+ G + +K+ D G+ S + + I W+ PE +
Sbjct 673 HRDLATRNCLV-------GENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESI- 724
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LAT 843
+T D W G L EI G+ P S +E + L P +CPQ +
Sbjct 725 -MYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYE 783
Query 844 LTSQCLTYEPTQR---PSFRTILRDLTRLQP 871
L C EP R S T+L++L + P
Sbjct 784 LMLGCWQREPHTRKNIKSIHTLLQNLAKASP 814
>sp|P25911|LYN_MOUSE Tyrosine-protein kinase Lyn OS=Mus musculus
OX=10090 GN=Lyn PE=1 SV=4
Length=512
Score = 164 bits (415), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 100/286 (35%), Positives = 152/286 (53%), Gaps = 28/286 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+K ++ LG G FG+V + Y N+ T VAVK LK G + +E ++++TL H
Sbjct 247 IKLVKKLGAGQFGEVWMGYY---NNSTK--VAVKTLKP--GTMSVQAFLEEANLMKTLQH 299
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAY 1013
+ +++ E+ + ++ E++ GSL D+L G L +L+ F+ QI EGMAY
Sbjct 300 DKLVRLYAVV--TKEEPIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAY 357
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ ++YIHRDL A NVL+ + KI DFGLA+ + + Y RE P+ W APE +
Sbjct 358 IERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAI 415
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
F SDVWSFG+ LYE++T+ I T + L +G R
Sbjct 416 NFGCFTIKSDVWSFGILLYEIVTYGK--------------IPYPGRTNADVMSALSQGYR 461
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+PR + CP E+Y +MK CW+ +A RPTF+ L +L + +GQ
Sbjct 462 MPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQ 507
Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 62/241 (26%), Positives = 115/241 (48%), Gaps = 23/241 (10%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P + AF E A+LM + H L ++ V + ++TE++ G L
Sbjct 271 KVAVKTLKPGTMSVQ-AFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLD 329
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ + G + K++ + Q+A ++Y+E KN +H ++ N+L++ S K
Sbjct 330 FLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSE-------SLMCK 382
Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
++D G+ + E R I W APE + G ++ + D W FG L EI
Sbjct 383 IADFGLAR-VIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKS--DVWSFGILLYEIVTY 439
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSF---RTILRD 865
G+ P R+ ++ + +R+P +CP +L + C + +RP+F +++L D
Sbjct 440 GKIPYPGRTNADVMSALSQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDD 499
Query 866 L 866
Sbjct 500 F 500
>sp|P53356|HTK16_HYDVU Tyrosine-protein kinase HTK16 OS=Hydra
vulgaris OX=6087 GN=HTK16 PE=2 SV=1
Length=757
Score = 168 bits (425), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 102/268 (38%), Positives = 143/268 (53%), Gaps = 22/268 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
++LG G FG V + + G E+ VA+K L D Q + +E ++ L H I
Sbjct 488 KELGVGEFGSVIKGIW--LSPGGKEINVAMKTLHKDKMVQGEKEFLREALVMSQLNHPCI 545
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + LV E V +G+L DYL + I L L+A QI GM YL +
Sbjct 546 VSLLGVCLG---PPMILVQELVEMGALLDYLMDYQPEIQEVDLKLWASQIAFGMMYLELK 602
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
++HRDLAARN+LL N + VKI DFGL++AV G +YY+ ++ G PV WYAPE +
Sbjct 603 RFVHRDLAARNILLANKKQVKISDFGLSRAVGTGSDYYQAKQGGRWPVRWYAPESINYGT 662
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWS+G+TL+E+ T D + G+MT + LE RL +P
Sbjct 663 FSTKSDVWSYGITLWEMFTFGD--------------LPYGEMTGNEVVSFLEHCGRLEKP 708
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165
D+CP Y +M +CW + + RPTF L
Sbjct 709 DECPIHTYSIMLSCWHIDPNKRPTFNEL 736
Score = 90.9 bits (224), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 80/249 (32%), Positives = 120/249 (48%), Gaps = 29/249 (12%)
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALA----FYETASLMSQVSHTHLAFVHGVCVRGPE 682
L PG G+E+ V +K L H D + F A +MSQ++H + + GVC+ GP
Sbjct 504 LSPG---GKEINVAMKTL---HKDKMVQGEKEFLREALVMSQLNHPCIVSLLGVCL-GPP 556
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
I+V E VE G L +L + + + A Q+A + YLE K VH ++ RNILL
Sbjct 557 MILVQELVEMGALLDYLMDYQPEIQEVDLKLWASQIAFGMMYLELKRFVHRDLAARNILL 616
Query 743 ARLGLAEGTSPFIKLSDPG----VGLGA-LSREERVERIP--WLAPECLPGGANSLSTAM 795
A +K+SD G VG G+ + ++ R P W APE + G + ST
Sbjct 617 A-------NKKQVKISDFGLSRAVGTGSDYYQAKQGGRWPVRWYAPESINYG--TFSTKS 667
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEP 853
D W +G TL E+ G+ P + +E F + RL +P CP ++ C +P
Sbjct 668 DVWSYGITLWEMFTFGDLPYGEMTGNEVVSFLEHCGRLEKPDECPIHTYSIMLSCWHIDP 727
Query 854 TQRPSFRTI 862
+RP+F +
Sbjct 728 NKRPTFNEL 736
>sp|Q91987|NTRK2_CHICK BDNF/NT-3 growth factors receptor OS=Gallus
gallus OX=9031 GN=NTRK2 PE=1 SV=1
Length=818
Score = 168 bits (426), Expect = 2e-41, Method: Compositional matrix adjust.
Identities = 109/295 (37%), Positives = 152/295 (52%), Gaps = 35/295 (12%)
Query 893 HKRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
H LK R+LGEG FGKV L CY+ + +VAVK LK D R + +E ++L
Sbjct 532 HNIVLK--RELGEGAFGKVFLAECYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELL 588
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------------IGL 997
L HEHI+K+ G C + L +V EY+ G L +L H +
Sbjct 589 TNLQHEHIVKFYGVCVEG--DPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNRPAELTQ 646
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+Q+L AQQI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV
Sbjct 647 SQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV-YSTDYYRV 705
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
P+ W PE + KF SDVWS GV L+E+ T+ + P
Sbjct 706 GGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTY---GKQP-----------WY 751
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
Q++ + E + +G L RP CP EVY LM CW+ E R + + +L+ +
Sbjct 752 QLSNNEVIECITQGRVLQRPRTCPKEVYDLMLGCWQREPHMRLNIKEIHSLLQNL 806
Score = 84.3 bits (207), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 74/271 (27%), Positives = 120/271 (44%), Gaps = 41/271 (15%)
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
L P +D+ + V +K L + + F+ A L++ + H H+ +GVCV G IMV
Sbjct 556 LCPEQDK---ILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMV 612
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMV---------------VAQQLASALSYLENKNLV 731
EY++HG L+ +L R H P A M +AQQ+A+ + YL +++ V
Sbjct 613 FEYMKHGDLNKFL---RAHGPDAVLMAEGNRPAELTQSQMLHIAQQIAAGMVYLASQHFV 669
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785
H ++ RN L+ G + +K+ D G+ S + + I W+ PE +
Sbjct 670 HRDLATRNCLV-------GENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESI- 721
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLAT 843
+T D W G L EI G+ P S +E + L P +CP ++
Sbjct 722 -MYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPKEVYD 780
Query 844 LTSQCLTYEPTQRPSFRTI---LRDLTRLQP 871
L C EP R + + I L++L + P
Sbjct 781 LMLGCWQREPHMRLNIKEIHSLLQNLAKASP 811
>sp|Q07014|LYN_RAT Tyrosine-protein kinase Lyn OS=Rattus norvegicus
OX=10116 GN=Lyn PE=1 SV=3
Length=512
Score = 163 bits (413), Expect = 3e-41, Method: Compositional matrix adjust.
Identities = 99/286 (35%), Positives = 151/286 (53%), Gaps = 28/286 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+K ++ LG G FG+V + Y N+ T VAVK LK G + +E ++++TL H
Sbjct 247 IKLVKKLGAGQFGEVWMGYY---NNSTK--VAVKTLKP--GTMSAQAFLEEANLMKTLQH 299
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAY 1013
+ +++ E+ + ++ E++ GSL D+L + L +L+ F+ QI EGMAY
Sbjct 300 DKLVRLYAVV--TKEEPIYIITEFMAKGSLLDFLKSDEGSKVLLPKLIDFSAQIAEGMAY 357
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ ++YIHRDL A NVL+ + KI DFGLA+ + + Y RE P+ W APE +
Sbjct 358 IERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAI 415
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
F SDVWSFG+ LYE++T+ I T + L +G R
Sbjct 416 NFGCFTIKSDVWSFGILLYEIVTYGK--------------IPYPGRTNADVMTALSQGYR 461
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+PR + CP E+Y +MK CW+ A RPTF+ L +L + +GQ
Sbjct 462 MPRMENCPDELYDIMKMCWKESAEERPTFDYLQSVLDDFYTATEGQ 507
Score = 84.0 bits (206), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 63/241 (26%), Positives = 114/241 (47%), Gaps = 23/241 (10%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P A AF E A+LM + H L ++ V + ++TE++ G L
Sbjct 271 KVAVKTLKPGTMS-AQAFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLD 329
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ + G + K++ + Q+A ++Y+E KN +H ++ N+L++ S K
Sbjct 330 FLKSDEGSKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSE-------SLMCK 382
Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
++D G+ + E R I W APE + G ++ + D W FG L EI
Sbjct 383 IADFGLAR-VIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKS--DVWSFGILLYEIVTY 439
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSF---RTILRD 865
G+ P R+ ++ + +R+P +CP +L + C +RP+F +++L D
Sbjct 440 GKIPYPGRTNADVMTALSQGYRMPRMENCPDELYDIMKMCWKESAEERPTFDYLQSVLDD 499
Query 866 L 866
Sbjct 500 F 500
>sp|Q95KR7|LCK_SAISC Proto-oncogene tyrosine-protein kinase LCK
OS=Saimiri sciureus OX=9521 GN=LCK PE=1 SV=3
Length=509
Score = 163 bits (412), Expect = 3e-41, Method: Compositional matrix adjust.
Identities = 103/289 (36%), Positives = 150/289 (52%), Gaps = 29/289 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+ LK + LG G FG+V + Y N+ T VAVK+LK G + E ++++
Sbjct 242 RETLKLVERLGAGQFGEVWMGYY---NEHT--KVAVKSLKQ--GSMSPDAFLAEANLMKQ 294
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEG 1010
L H+ +++ E+ + ++ EY+ GSL D+L S + + +LL A QI EG
Sbjct 295 LQHKRLVRLYAVVT---EEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIVEG 351
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
MA+L ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W AP
Sbjct 352 MAFLEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKWTAP 409
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E + F SDVWSFG+ + E++TH I MT + + LER
Sbjct 410 EAINYGTFTIKSDVWSFGILMTEIVTHGR--------------IPYPGMTNPEVIQNLER 455
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
G R+PRPD CP E+Y LM CW RPTF+ L +L+ +GQ
Sbjct 456 GYRMPRPDNCPEELYKLMMQCWRERPDDRPTFDYLRSVLEDFFTATEGQ 504
Score = 85.1 bits (209), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 68/226 (30%), Positives = 108/226 (48%), Gaps = 25/226 (11%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
AF A+LM Q+ H L ++ V P I +TEY+E+G L +L+ G K++
Sbjct 284 AFLAEANLMKQLQHKRLVRLYAVVTEEPIYI-ITEYMENGSLVDFLKTPSGIKLTINKLL 342
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----- 767
+A Q+ +++LE +N +H ++ NIL++ + K++D GL L
Sbjct 343 DMAAQIVEGMAFLEERNYIHRDLRAANILVS-------DTLSCKIAD--FGLARLIEDNE 393
Query 768 --SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
+RE I W APE + G ++ + D W FG + EI G P + E
Sbjct 394 YTAREGAKFPIKWTAPEAINYGTFTIKS--DVWSFGILMTEIVTHGRIPYPGMTNPEVIQ 451
Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF---RTILRDL 866
+R +R+P P +CP +L L QC P RP+F R++L D
Sbjct 452 NLERGYRMPRPDNCPEELYKLMMQCWRERPDDRPTFDYLRSVLEDF 497
>sp|P42679|MATK_HUMAN Megakaryocyte-associated tyrosine-protein
kinase OS=Homo sapiens OX=9606 GN=MATK PE=1 SV=1
Length=507
Score = 163 bits (412), Expect = 3e-41, Method: Compositional matrix adjust.
Identities = 106/286 (37%), Positives = 153/286 (53%), Gaps = 37/286 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG V Y G+ VAVK +K D Q + E ++ + HE++++
Sbjct 241 IGEGEFGAVLQGEY------LGQKVAVKNIKCDVTAQ---AFLDETAVMTKMQHENLVRL 291
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
G QG L +VME+V G+L ++L R + AQLL F+ + EGM YL ++
Sbjct 292 LGVILHQG---LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKL 348
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDLAARN+L+ D + K+ DFGLAKA +G + R+ PV W APE LK KF
Sbjct 349 VHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRL------PVKWTAPEALKHGKFT 402
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SDVWSFGV L+E+ ++ ++P K M++ ++E +E+G R+ P+
Sbjct 403 SKSDVWSFGVLLWEVFSY---GRAPYPK-----------MSLKEVSEAVEKGYRMEPPEG 448
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
CP V+ LM +CWE E + RP F L K E AP+ S
Sbjct 449 CPGPVHVLMSSCWEAEPARRPPFRKLAE--KLARELRSAGAPASVS 492
Score = 87.4 bits (215), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 74/226 (33%), Positives = 109/226 (48%), Gaps = 24/226 (11%)
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAW 710
A AF + ++M+++ H +L + GV + I V E+V G L +LR R R V A
Sbjct 270 AQAFLDETAVMTKMQHENLVRLLGVILHQGLYI-VMEHVSKGNLVNFLRTRGRALVNTAQ 328
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ + +A + YLE+K LVH ++ RNIL++ +A K+SD G L++
Sbjct 329 LLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVA-------KVSDFG-----LAKA 376
Query 771 ER----VERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
ER R+P W APE L G ++ D W FG L E+ G AP S E
Sbjct 377 ERKGLDSSRLPVKWTAPEALKHG--KFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVS 434
Query 825 HFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTR 868
++ +R+ P CP + L S C EP +RP FR + L R
Sbjct 435 EAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLAR 480
>sp|Q61527|ERBB4_MOUSE Receptor tyrosine-protein kinase erbB-4
OS=Mus musculus OX=10090 GN=Erbb4 PE=1 SV=5
Length=1308
Score = 169 bits (428), Expect = 3e-41, Method: Compositional matrix adjust.
Identities = 108/305 (35%), Positives = 159/305 (52%), Gaps = 21/305 (7%)
Query 864 RDLTRLQPHNLADVLTVNPDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922
R L R L + LT + +P + + + LK+++ LG G FG V + P +
Sbjct 684 RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGET 743
Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982
VA+K L GP+ + E I+ ++ H H+++ G C ++QLV + +P
Sbjct 744 VKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCL---SPTIQLVTQLMP 800
Query 983 LGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040
G L DY+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI
Sbjct 801 HGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKIT 860
Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100
DFGLA+ + EG E + G P+ W A EC+ KF + SDVWS+GVT++EL+T
Sbjct 861 DFGLARLL-EGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMT---- 915
Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
G + + +LLE+GERLP+P C +VY +M CW +A RP
Sbjct 916 ----------FGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRP 965
Query 1161 TFENL 1165
F+ L
Sbjct 966 KFKEL 970
Score = 76.6 bits (187), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 69/302 (23%), Positives = 129/302 (43%), Gaps = 39/302 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+Q + + E+ ++ LG G VY+G EG E +P
Sbjct 706 NQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEG-----------ETVKIP------- 747
Query 637 LRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K+L+ + A + F + A +M+ + H HL + GVC+ P +VT+ + HG L
Sbjct 748 --VAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCL-SPTIQLVTQLMPHGCL 804
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
++ + ++ + Q+A + YLE + LVH ++ RN+L+ + +
Sbjct 805 LDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVK-------SPNHV 857
Query 756 KLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
K++D G+ L +E + I W+A EC+ + D W +G T+ E+
Sbjct 858 KITDFGLARLLEGDEKEYNADGGKMPIKWMALECI--HYRKFTHQSDVWSYGVTIWELMT 915
Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLT 867
G P E ++ RLP+P + + +C + RP F+ + + +
Sbjct 916 FGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFS 975
Query 868 RL 869
R+
Sbjct 976 RM 977
>sp|Q5PXS1|LCK_AOTNA Tyrosine-protein kinase Lck OS=Aotus nancymaae
OX=37293 GN=LCK PE=2 SV=4
Length=509
Score = 162 bits (411), Expect = 4e-41, Method: Compositional matrix adjust.
Identities = 103/289 (36%), Positives = 151/289 (52%), Gaps = 29/289 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+ LK + LG G FG+V + Y ND T VAVK+LK G + E ++++
Sbjct 242 RETLKLVERLGAGQFGEVWMGYY---NDHT--KVAVKSLKQ--GSMSPDAFLAEANLMKQ 294
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEG 1010
L H+ +++ ++ + ++ EY+ GSL D+L S + + +LL A QI EG
Sbjct 295 LQHQRLVRLYAVVT---QEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEG 351
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
MA++ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W AP
Sbjct 352 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKWTAP 409
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E + F SDVWSFG+ L E++TH I MT + + LER
Sbjct 410 EAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQNLER 455
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
G R+ RPD CP E+YHLM CW+ RPTF+ L +L+ +GQ
Sbjct 456 GYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLEDFFTATEGQ 504
Score = 80.1 bits (196), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 67/226 (30%), Positives = 108/226 (48%), Gaps = 25/226 (11%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
AF A+LM Q+ H L ++ V + P I +TEY+E+G L +L+ G K++
Sbjct 284 AFLAEANLMKQLQHQRLVRLYAVVTQEPIYI-ITEYMENGSLVDFLKTPSGIKLTINKLL 342
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----- 767
+A Q+A ++++E +N +H ++ NIL++ + K++D GL L
Sbjct 343 DMAAQIAEGMAFIEERNYIHRDLRAANILVS-------DTLSCKIAD--FGLARLIEDNE 393
Query 768 --SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
+RE I W APE + G ++ + D W FG L EI G P + E
Sbjct 394 YTAREGAKFPIKWTAPEAINYGTFTIKS--DVWSFGILLTEIVTHGRIPYPGMTNPEVIQ 451
Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF---RTILRDL 866
+R +R+ P +CP +L L C P RP+F R++L D
Sbjct 452 NLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLEDF 497
>sp|Q14289|FAK2_HUMAN Protein-tyrosine kinase 2-beta OS=Homo sapiens
OX=9606 GN=PTK2B PE=1 SV=2
Length=1009
Score = 168 bits (426), Expect = 4e-41, Method: Compositional matrix adjust.
Identities = 103/279 (37%), Positives = 154/279 (55%), Gaps = 28/279 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LGEG FG+V Y + G VAVK K DC ++ + E I++ L H HI+
Sbjct 429 RILGEGFFGEVYEGVYT-NHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIV 487
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQH 1018
K G E E+ ++ME P G L YL R+ S+ + L+L++ QIC+ MAYL + +
Sbjct 488 KLIGIIE---EEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESIN 544
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRD+A RN+L+ + VK+GDFGL++ + E +YY+ P+ W +PE + +F
Sbjct 545 CVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKA-SVTRLPIKWMSPESINFRRF 602
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE---LIGIAQGQMTVLRLTELLERGERLP 1135
ASDVW F V ++E+L+ P +LE +IG+ LE+G+RLP
Sbjct 603 TTASDVWMFAVCMWEILSFGKQ----PFFWLENKDVIGV-------------LEKGDRLP 645
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+PD CP +Y LM CW+ + S RP F L+ L V++
Sbjct 646 KPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQ 684
Score = 84.0 bits (206), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 66/245 (27%), Positives = 113/245 (46%), Gaps = 22/245 (9%)
Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+G+++ V +K D F A +M + H H+ + G+ P I + E
Sbjct 448 KGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWI-IMELYP 506
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
+G L +L R + + + ++ + Q+ A++YLE+ N VH ++ RNIL+A +
Sbjct 507 YGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVA-------S 559
Query 752 SPFIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATL 804
+KL D GL +E V R+P W++PE + +TA D W F +
Sbjct 560 PECVKLGD--FGLSRYIEDEDYYKASVTRLPIKWMSPESI--NFRRFTTASDVWMFAVCM 615
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC--PQLATLTSQCLTYEPTQRPSFRTI 862
EI G+ P + ++ RLP+P P L TL ++C Y+P+ RP F +
Sbjct 616 WEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTEL 675
Query 863 LRDLT 867
+ L+
Sbjct 676 VCSLS 680
>sp|P41241|CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus musculus
OX=10090 GN=Csk PE=1 SV=2
Length=450
Score = 161 bits (407), Expect = 5e-41, Method: Compositional matrix adjust.
Identities = 100/278 (36%), Positives = 146/278 (53%), Gaps = 35/278 (13%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
+ + LK ++ +G+G FG V L D G VAVK +K D Q + E ++
Sbjct 190 LNMKELKLLQTIGKGEFGDVML------GDYRGNKVAVKCIKNDATAQ---AFLAEASVM 240
Query 952 RTLYHEHIIKYKGC-CEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQI 1007
L H ++++ G E++G L +V EY+ GSL DYL R +G LL F+ +
Sbjct 241 TQLRHSNLVQLLGVIVEEKG--GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDV 298
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
CE M YL +++HRDLAARNVL+ D + K+ DFGL K E ++ G PV W
Sbjct 299 CEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------EASSTQDTGKLPVKW 352
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE L+E KF SDVWSFG+ L+E+ + + ++ + +
Sbjct 353 TAPEALREKKFSTKSDVWSFGILLWEIYSFGR--------------VPYPRIPLKDVVPR 398
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+E+G ++ PD CP VY +MKNCW +A+ RPTF L
Sbjct 399 VEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPTFLQL 436
Score = 78.2 bits (191), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 66/231 (29%), Positives = 106/231 (46%), Gaps = 20/231 (9%)
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLR-RERGHVPMA 709
A AF AS+M+Q+ H++L + GV V + +VTEY+ G L +LR R R +
Sbjct 230 AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD 289
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+ + + A+ YLE N VH ++ RN+L++ +A K+SD G+ A S
Sbjct 290 CLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVA-------KVSDFGLTKEASST 342
Query 770 EERVER-IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA-----PLQSRSPSEK 823
++ + + W APE L ST D W FG L EI G PL+ P +
Sbjct 343 QDTGKLPVKWTAPEALR--EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVE 400
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
+ + + P+ P + + C + RP+F + L ++ H L
Sbjct 401 KGY---KMDAPDGCPPAVYEVMKNCWHLDAATRPTFLQLREQLEHIKTHEL 448
>sp|P32577|CSK_RAT Tyrosine-protein kinase CSK OS=Rattus norvegicus
OX=10116 GN=Csk PE=1 SV=1
Length=450
Score = 161 bits (407), Expect = 5e-41, Method: Compositional matrix adjust.
Identities = 100/278 (36%), Positives = 146/278 (53%), Gaps = 35/278 (13%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
+ + LK ++ +G+G FG V L D G VAVK +K D Q + E ++
Sbjct 190 LNMKELKLLQTIGKGEFGDVML------GDYRGNKVAVKCIKNDATAQ---AFLAEASVM 240
Query 952 RTLYHEHIIKYKGC-CEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQI 1007
L H ++++ G E++G L +V EY+ GSL DYL R +G LL F+ +
Sbjct 241 TQLRHSNLVQLLGVIVEEKG--GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDV 298
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
CE M YL +++HRDLAARNVL+ D + K+ DFGL K E ++ G PV W
Sbjct 299 CEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------EASSTQDTGKLPVKW 352
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE L+E KF SDVWSFG+ L+E+ + + ++ + +
Sbjct 353 TAPEALREKKFSTKSDVWSFGILLWEIYSFGR--------------VPYPRIPLKDVVPR 398
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+E+G ++ PD CP VY +MKNCW +A+ RPTF L
Sbjct 399 VEKGYKMDAPDGCPPAVYDVMKNCWHLDAATRPTFLQL 436
Score = 78.2 bits (191), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 66/231 (29%), Positives = 106/231 (46%), Gaps = 20/231 (9%)
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLR-RERGHVPMA 709
A AF AS+M+Q+ H++L + GV V + +VTEY+ G L +LR R R +
Sbjct 230 AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD 289
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+ + + A+ YLE N VH ++ RN+L++ +A K+SD G+ A S
Sbjct 290 CLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVA-------KVSDFGLTKEASST 342
Query 770 EERVER-IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA-----PLQSRSPSEK 823
++ + + W APE L ST D W FG L EI G PL+ P +
Sbjct 343 QDTGKLPVKWTAPEALR--EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVE 400
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
+ + + P+ P + + C + RP+F + L ++ H L
Sbjct 401 KGY---KMDAPDGCPPAVYDVMKNCWHLDAATRPTFLQLREQLEHIRTHEL 448
>sp|P04629|NTRK1_HUMAN High affinity nerve growth factor receptor
OS=Homo sapiens OX=9606 GN=NTRK1 PE=1 SV=4
Length=796
Score = 167 bits (422), Expect = 5e-41, Method: Compositional matrix adjust.
Identities = 110/319 (34%), Positives = 160/319 (50%), Gaps = 46/319 (14%)
Query 887 SDPTVFH--KRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSG 943
SD V H +R + +LGEG FGKV L C++ + +VAVKALK + R
Sbjct 498 SDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALK-EASESARQD 556
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------- 994
+++E ++L L H+HI+++ G C + + L +V EY+ G L +L H
Sbjct 557 FQREAELLTMLQHQHIVRFFGVCTEG--RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGG 614
Query 995 -------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
+GL QLL A Q+ GM YL H++HRDLA RN L+ +VKIGDFG+++
Sbjct 615 EDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRD 674
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ +YYRV P+ W PE + KF SDVWSFGV L+E+ T+
Sbjct 675 I-YSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY---- 729
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
Q++ + + +G L RP CP EVY +M+ CW+ E R +
Sbjct 730 ----------QLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHS------ 773
Query 1168 ILKTVHEKYQ--GQAPSVF 1184
+K VH + Q QAP V+
Sbjct 774 -IKDVHARLQALAQAPPVY 791
Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 74/309 (24%), Positives = 123/309 (40%), Gaps = 50/309 (16%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
S H + +++I LG+G V+ + + L+P +D+
Sbjct 497 FSDACVHHIKRRDIVLKWELGEGAFGKVF----------------LAECHNLLPEQDK-- 538
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+ V +K L + F A L++ + H H+ GVC G +MV EY+ HG L
Sbjct 539 -MLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDL 597
Query 696 DVWLRRER--------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
+ +LR G + + + VA Q+A+ + YL + VH ++ RN L
Sbjct 598 NRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCL 657
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAM 795
+ G +K+ D G+ S + + I W+ PE + +T
Sbjct 658 V-------GQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESIL--YRKFTTES 708
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEP 853
D W FG L EI G+ P S +E + L P +C P++ + C EP
Sbjct 709 DVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREP 768
Query 854 TQRPSFRTI 862
QR S + +
Sbjct 769 QQRHSIKDV 777
>sp|P41242|MATK_MOUSE Megakaryocyte-associated tyrosine-protein
kinase OS=Mus musculus OX=10090 GN=Matk PE=1 SV=2
Length=505
Score = 162 bits (409), Expect = 6e-41, Method: Compositional matrix adjust.
Identities = 100/270 (37%), Positives = 147/270 (54%), Gaps = 35/270 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG V Y G+ VAVK +K D Q + E ++ L H ++++
Sbjct 239 IGEGEFGAVLQGEY------LGQKVAVKNIKCDVTAQ---AFLDETAVMTKLQHRNLVRL 289
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
G G L +VME+V G+L ++L R + +QLL FA + EGM YL ++
Sbjct 290 LGVILHHG---LYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKL 346
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDLAARN+L+ D + K+ DFGLAKA +G + R+ PV W APE LK +F
Sbjct 347 VHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRL------PVKWTAPEALKNGRFS 400
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SDVWSFGV L+E+ ++ ++P K M++ ++E +E+G R+ PD
Sbjct 401 SKSDVWSFGVLLWEVFSY---GRAPYPK-----------MSLKEVSEAVEKGYRMEPPDG 446
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
CP V+ LM +CWE E + RP F ++ L
Sbjct 447 CPGSVHTLMGSCWEAEPARRPPFRKIVEKL 476
Score = 91.3 bits (225), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 76/226 (34%), Positives = 110/226 (49%), Gaps = 24/226 (11%)
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAW 710
A AF + ++M+++ H +L + GV + I V E+V G L +LR R R V +
Sbjct 268 AQAFLDETAVMTKLQHRNLVRLLGVILHHGLYI-VMEHVSKGNLVNFLRTRGRALVSTSQ 326
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ A +A + YLE+K LVH ++ RNIL++ +A K+SD G L++
Sbjct 327 LLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVA-------KVSDFG-----LAKA 374
Query 771 ER----VERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
ER R+P W APE L G S+ D W FG L E+ G AP S E
Sbjct 375 ERKGLDSSRLPVKWTAPEALKNG--RFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVS 432
Query 825 HFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTR 868
++ +R+ P CP + TL C EP +RP FR I+ L R
Sbjct 433 EAVEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRKIVEKLGR 478
>sp|Q16288|NTRK3_HUMAN NT-3 growth factor receptor OS=Homo sapiens
OX=9606 GN=NTRK3 PE=1 SV=2
Length=839
Score = 166 bits (421), Expect = 7e-41, Method: Compositional matrix adjust.
Identities = 113/302 (37%), Positives = 155/302 (51%), Gaps = 52/302 (17%)
Query 901 RDLGEGHFGKVSLY-CYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
R+LGEG FGKV L CY+ PT D +VAVKALK D R +++E ++L L HE
Sbjct 542 RELGEGAFGKVFLAECYNLSPTKDKM--LVAVKALK-DPTLAARKDFQREAELLTNLQHE 598
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQL 1000
HI+K+ G C D L +V EY+ G L +L H +GL+Q+
Sbjct 599 HIVKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQM 656
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV----------PE 1050
L A QI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V P
Sbjct 657 LHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRLFNPS 716
Query 1051 GHEYYRVREDGDS---PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
G+++ E G P+ W PE + KF SDVWSFGV L+E+ T+ + P
Sbjct 717 GNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY---GKQP--- 770
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
Q++ + E + +G L RP CP EVY +M CW+ E R + +
Sbjct 771 --------WFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYK 822
Query 1168 IL 1169
IL
Sbjct 823 IL 824
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 70/280 (25%), Positives = 116/280 (41%), Gaps = 49/280 (18%)
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
L P +D+ + V +K L F A L++ + H H+ +GVC G IMV
Sbjct 560 LSPTKDK---MLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMV 616
Query 687 TEYVEHGPLDVWL---------------RRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
EY++HG L+ +L R+ +G + ++ + +A Q+AS + YL +++ V
Sbjct 617 FEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFV 676
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE--------------------E 771
H ++ RN L+ G + +K+ D G+ S +
Sbjct 677 HRDLATRNCLV-------GANLLVKIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGH 729
Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
+ I W+ PE + +T D W FG L EI G+ P S +E +
Sbjct 730 TMLPIRWMPPESI--MYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGR 787
Query 832 RLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
L P CP ++ + C EP QR + + I + L L
Sbjct 788 VLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 827
>sp|P41240|CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo sapiens
OX=9606 GN=CSK PE=1 SV=1
Length=450
Score = 160 bits (405), Expect = 7e-41, Method: Compositional matrix adjust.
Identities = 99/278 (36%), Positives = 146/278 (53%), Gaps = 35/278 (13%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
+ + LK ++ +G+G FG V L D G VAVK +K D Q + E ++
Sbjct 190 LNMKELKLLQTIGKGEFGDVML------GDYRGNKVAVKCIKNDATAQ---AFLAEASVM 240
Query 952 RTLYHEHIIKYKGC-CEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQI 1007
L H ++++ G E++G L +V EY+ GSL DYL R +G LL F+ +
Sbjct 241 TQLRHSNLVQLLGVIVEEKG--GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDV 298
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
CE M YL +++HRDLAARNVL+ D + K+ DFGL K E ++ G PV W
Sbjct 299 CEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------EASSTQDTGKLPVKW 352
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE L+E KF SDVWSFG+ L+E+ + + ++ + +
Sbjct 353 TAPEALREKKFSTKSDVWSFGILLWEIYSFGR--------------VPYPRIPLKDVVPR 398
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+E+G ++ PD CP VY +MKNCW +A+ RP+F L
Sbjct 399 VEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQL 436
Score = 79.3 bits (194), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 67/231 (29%), Positives = 106/231 (46%), Gaps = 20/231 (9%)
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLR-RERGHVPMA 709
A AF AS+M+Q+ H++L + GV V + +VTEY+ G L +LR R R +
Sbjct 230 AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD 289
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+ + + A+ YLE N VH ++ RN+L++ +A K+SD G+ A S
Sbjct 290 CLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVA-------KVSDFGLTKEASST 342
Query 770 EERVER-IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA-----PLQSRSPSEK 823
++ + + W APE L ST D W FG L EI G PL+ P +
Sbjct 343 QDTGKLPVKWTAPEALR--EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVE 400
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
+ + + P+ P + + C + RPSF + L ++ H L
Sbjct 401 KGY---KMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTHEL 448
>sp|P70600|FAK2_RAT Protein-tyrosine kinase 2-beta OS=Rattus norvegicus
OX=10116 GN=Ptk2b PE=1 SV=1
Length=1009
Score = 167 bits (423), Expect = 8e-41, Method: Compositional matrix adjust.
Identities = 104/279 (37%), Positives = 154/279 (55%), Gaps = 28/279 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LGEG FG+V Y + G VAVK K DC ++ + E I++ L H HI+
Sbjct 429 RILGEGFFGEVYEGVYT-NHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIV 487
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQH 1018
K G E E+ +VME P G L YL R+ S+ + L+L+A QIC+ MAYL + +
Sbjct 488 KLIGIIE---EEPTWIVMELYPYGELGHYLERNKNSLKVPTLVLYALQICKAMAYLESIN 544
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRD+A RN+L+ + VK+GDFGL++ + E +YY+ P+ W +PE + +F
Sbjct 545 CVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKA-SVTRLPIKWMSPESINFRRF 602
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE---LIGIAQGQMTVLRLTELLERGERLP 1135
ASDVW F V ++E+L S P +LE +IG+ LE+G+RLP
Sbjct 603 TTASDVWMFAVCMWEIL----SFGKQPFFWLENKDVIGV-------------LEKGDRLP 645
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+P+ CP +Y LM CW+ + S RP F L+ L +++
Sbjct 646 KPELCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDIYQ 684
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 68/247 (28%), Positives = 114/247 (46%), Gaps = 22/247 (9%)
Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+G+++ V +K D F A +M + H H+ + G+ P I V E
Sbjct 448 KGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWI-VMELYP 506
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
+G L +L R + + + ++ A Q+ A++YLE+ N VH ++ RNIL+A +
Sbjct 507 YGELGHYLERNKNSLKVPTLVLYALQICKAMAYLESINCVHRDIAVRNILVA-------S 559
Query 752 SPFIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATL 804
+KL D GL +E V R+P W++PE + +TA D W F +
Sbjct 560 PECVKLGD--FGLSRYIEDEDYYKASVTRLPIKWMSPESI--NFRRFTTASDVWMFAVCM 615
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC--PQLATLTSQCLTYEPTQRPSFRTI 862
EI G+ P + ++ RLP+P P L TL ++C Y+P+ RP F +
Sbjct 616 WEILSFGKQPFFWLENKDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDYDPSDRPRFTEL 675
Query 863 LRDLTRL 869
+ L+ +
Sbjct 676 VCSLSDI 682
>sp|Q0VBZ0|CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos taurus
OX=9913 GN=CSK PE=2 SV=1
Length=450
Score = 160 bits (404), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 97/272 (36%), Positives = 143/272 (53%), Gaps = 33/272 (12%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
LK ++ +G+G FG V L D G VAVK +K D Q + E ++ L H
Sbjct 195 LKLLQTIGKGEFGDVML------GDYRGNKVAVKCIKNDATAQ---AFLAEASVMTQLRH 245
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAY 1013
++++ G ++ + L +V EY+ GSL DYL R +G LL F+ +CE M Y
Sbjct 246 SNLVQLLGVIVEE-KSGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEY 304
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
L +++HRDLAARNVL+ D + K+ DFGL K E ++ G PV W APE L
Sbjct 305 LEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------EASSTQDTGKLPVKWTAPEAL 358
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+E KF SDVWSFG+ L+E+ + + ++ + + +E+G +
Sbjct 359 REKKFSTKSDVWSFGILLWEIYSFGR--------------VPYPRIPLKDVVPRVEKGYK 404
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ PD CP VY +MKNCW +A+ RP+F L
Sbjct 405 MDAPDGCPPAVYEVMKNCWHLDAATRPSFLQL 436
Score = 82.4 bits (202), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 68/231 (29%), Positives = 107/231 (46%), Gaps = 20/231 (9%)
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLR-RERGHVPMA 709
A AF AS+M+Q+ H++L + GV V + +VTEY+ G L +LR R R +
Sbjct 230 AQAFLAEASVMTQLRHSNLVQLLGVIVEEKSGLYIVTEYMAKGSLVDYLRSRGRSVLGGD 289
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+ + + A+ YLE N VH ++ RN+L++ +A K+SD G+ A S
Sbjct 290 CLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVA-------KVSDFGLTKEASST 342
Query 770 EERVER-IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA-----PLQSRSPSEK 823
++ + + W APE L ST D W FG L EI G PL+ P +
Sbjct 343 QDTGKLPVKWTAPEALR--EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVE 400
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
+ + + P+ P + + C + RPSF + L R++ H L
Sbjct 401 KGY---KMDAPDGCPPAVYEVMKNCWHLDAATRPSFLQLREQLERIKTHEL 448
>sp|Q15303|ERBB4_HUMAN Receptor tyrosine-protein kinase erbB-4
OS=Homo sapiens OX=9606 GN=ERBB4 PE=1 SV=1
Length=1308
Score = 167 bits (423), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 107/305 (35%), Positives = 159/305 (52%), Gaps = 21/305 (7%)
Query 864 RDLTRLQPHNLADVLTVNPDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922
R L R L + LT + +P + + + LK+++ LG G FG V + P +
Sbjct 684 RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGET 743
Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982
VA+K L GP+ + E I+ ++ H H+++ G C ++QLV + +P
Sbjct 744 VKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCL---SPTIQLVTQLMP 800
Query 983 LGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040
G L +Y+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI
Sbjct 801 HGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKIT 860
Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100
DFGLA+ + EG E + G P+ W A EC+ KF + SDVWS+GVT++EL+T
Sbjct 861 DFGLARLL-EGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMT---- 915
Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
G + + +LLE+GERLP+P C +VY +M CW +A RP
Sbjct 916 ----------FGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRP 965
Query 1161 TFENL 1165
F+ L
Sbjct 966 KFKEL 970
Score = 76.6 bits (187), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 70/309 (23%), Positives = 131/309 (42%), Gaps = 39/309 (13%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P +Q + + E+ ++ LG G VY+G EG E +P
Sbjct 699 TPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEG-----------ETVKIP 747
Query 630 GRDRGQELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
V +K+L+ + A + F + A +M+ + H HL + GVC+ P +VT+
Sbjct 748 ---------VAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCL-SPTIQLVTQ 797
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ HG L ++ + ++ + Q+A + YLE + LVH ++ RN+L+
Sbjct 798 LMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVK----- 852
Query 749 EGTSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGA 802
+ +K++D G+ L +E + I W+A EC+ + D W +G
Sbjct 853 --SPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECI--HYRKFTHQSDVWSYGV 908
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFR 860
T+ E+ G P E ++ RLP+P + + +C + RP F+
Sbjct 909 TIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFK 968
Query 861 TILRDLTRL 869
+ + +R+
Sbjct 969 ELAAEFSRM 977
>sp|P06240|LCK_MOUSE Proto-oncogene tyrosine-protein kinase LCK
OS=Mus musculus OX=10090 GN=Lck PE=1 SV=4
Length=509
Score = 160 bits (406), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 101/289 (35%), Positives = 147/289 (51%), Gaps = 29/289 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+ LK + LG G FG+V + Y+ VAVK+LK G + E ++++
Sbjct 242 RETLKLVERLGAGQFGEVWMGYYNGHTK-----VAVKSLKQ--GSMSPDAFLAEANLMKQ 294
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEG 1010
L H +++ ++ + ++ EY+ GSL D+L S + + +LL A QI EG
Sbjct 295 LQHPRLVRLYAVVT---QEPIYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQIAEG 351
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
MA++ Q+YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W AP
Sbjct 352 MAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKWTAP 409
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E + F SDVWSFG+ L E++TH I MT + + LER
Sbjct 410 EAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQNLER 455
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
G R+ RPD CP E+YHLM CW+ RPTF+ L +L +GQ
Sbjct 456 GYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLDDFFTATEGQ 504
Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 67/226 (30%), Positives = 108/226 (48%), Gaps = 25/226 (11%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
AF A+LM Q+ H L ++ V + P I +TEY+E+G L +L+ G K++
Sbjct 284 AFLAEANLMKQLQHPRLVRLYAVVTQEPIYI-ITEYMENGSLVDFLKTPSGIKLNVNKLL 342
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----- 767
+A Q+A ++++E +N +H ++ NIL++ + K++D GL L
Sbjct 343 DMAAQIAEGMAFIEEQNYIHRDLRAANILVS-------DTLSCKIAD--FGLARLIEDNE 393
Query 768 --SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
+RE I W APE + G ++ + D W FG L EI G P + E
Sbjct 394 YTAREGAKFPIKWTAPEAINYGTFTIKS--DVWSFGILLTEIVTHGRIPYPGMTNPEVIQ 451
Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF---RTILRDL 866
+R +R+ P +CP +L L C P RP+F R++L D
Sbjct 452 NLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLDDF 497
>sp|P42689|SRK3_SPOLA Tyrosine-protein kinase SRK3 (Fragment)
OS=Spongilla lacustris OX=6055 GN=SRK3 PE=2 SV=1
Length=334
Score = 156 bits (394), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 97/276 (35%), Positives = 148/276 (54%), Gaps = 28/276 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LG+G+FG+V ++ T VAVK LK D + QE +++ ++H +++
Sbjct 70 RKLGQGNFGEVWAGVWNGTT-----AVAVKTLKPDT--MEVKDFVQEAQVMKKIHHPNLL 122
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ C GE + +V E + GS+ +YL +I L Q++ + QI GM YL A
Sbjct 123 QLYAVCT-IGE-PIYIVTELMKYGSMLEYLKHGEGKNITLHQMVDMSAQIASGMTYLEAH 180
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
YIHRDLAARN+L+ + K+ DFGLA+ + E + Y RE P+ W APE +
Sbjct 181 SYIHRDLAARNILVGEGNVCKVADFGLARVIKE--DIYNPREGTKFPIKWTAPEAALYNR 238
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFGV + E++TH + MT ++ E ++RG R+P P
Sbjct 239 FTIKSDVWSFGVLISEIVTHGR--------------MPYPGMTNRQVLEAVDRGYRMPCP 284
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ CP +Y +M +CW+ E RPTFE+L +L+ +
Sbjct 285 EGCPDPLYKIMLSCWKHEPDDRPTFESLKNLLEDYY 320
Score = 86.3 bits (212), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 64/234 (27%), Positives = 108/234 (46%), Gaps = 22/234 (9%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K L P ++ F + A +M ++ H +L ++ VC G +VTE +++G + +
Sbjct 91 VAVKTLKPDTMEVK-DFVQEAQVMKKIHHPNLLQLYAVCTIGEPIYIVTELMKYGSMLEY 149
Query 699 LRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
L+ G +MV ++ Q+AS ++YLE + +H ++ RNIL+ G K+
Sbjct 150 LKHGEGKNITLHQMVDMSAQIASGMTYLEAHSYIHRDLAARNILV-------GEGNVCKV 202
Query 758 SDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+D GL + +E+ I W APE N + D W FG + EI
Sbjct 203 AD--FGLARVIKEDIYNPREGTKFPIKWTAPEA--ALYNRFTIKSDVWSFGVLISEIVTH 258
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
G P + + R +R+P P CP L + C +EP RP+F ++
Sbjct 259 GRMPYPGMTNRQVLEAVDRGYRMPCPEGCPDPLYKIMLSCWKHEPDDRPTFESL 312
>sp|P11273|ERBB_AVIEU Tyrosine-protein kinase transforming protein
erbB OS=Avian erythroblastosis virus (strain ts167) OX=103898
GN=V-ERBB PE=3 SV=1
Length=540
Score = 161 bits (408), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 107/307 (35%), Positives = 161/307 (52%), Gaps = 22/307 (7%)
Query 864 RDLTRL-QPHNLADVLTVNPDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
R L RL Q L + LT + ++P + + + KK++ LG G FG V + P +
Sbjct 97 RTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKVKVLGFGAFGTVYKGLWIPEGE 156
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VA+K L+ P+ E ++ ++ + H+ + G C ++QL+ + +
Sbjct 157 KVTIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS---TVQLITQLM 213
Query 982 PLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P G L DY+ H +IG LL + QI +GM YL +H +HRDLAARNVL+ + VKI
Sbjct 214 PYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERHMVHRDLAARNVLVKTPQHVKI 273
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLAK + + Y E G P+ W A E + + + SDVWS+GVT++EL+T
Sbjct 274 TDFGLAKQLGADEKEYHA-EGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTF-- 330
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
S P GI + ++ +LE+GERLP+P C +VY +M CW ++A R
Sbjct 331 --GSKPYD-----GIPASE-----ISSVLEKGERLPQPPICTIDVYMIMVKCWMSDADSR 378
Query 1160 PTFENLI 1166
P F LI
Sbjct 379 PKFRELI 385
Score = 73.9 bits (180), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 51/221 (23%), Positives = 108/221 (49%), Gaps = 18/221 (8%)
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
+ A +M+ V + H+ + G+C+ ++T+ + +G L ++R + ++ + +
Sbjct 181 DEAYVMASVDNPHVCRLLGICLTSTVQ-LITQLMPYGCLLDYIREHKDNIGSQYLLNWCV 239
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE 774
Q+A ++YLE +++VH ++ RN+L+ T +K++D G+ LGA +E E
Sbjct 240 QIAKGMNYLEERHMVHRDLAARNVLVK-------TPQHVKITDFGLAKQLGADEKEYHAE 292
Query 775 --RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
++P W+A E + + + D W +G T+ E+ G P SE ++
Sbjct 293 GGKVPIKWMALESILHRIYTHQS--DVWSYGVTVWELMTFGSKPYDGIPASEISSVLEKG 350
Query 831 HRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869
RLP+P + + +C + RP FR ++ + +++
Sbjct 351 ERLPQPPICTIDVYMIMVKCWMSDADSRPKFRELIAEFSKM 391
>sp|P41243|MATK_RAT Megakaryocyte-associated tyrosine-protein
kinase OS=Rattus norvegicus OX=10116 GN=Matk PE=2 SV=1
Length=467
Score = 160 bits (404), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 100/270 (37%), Positives = 145/270 (54%), Gaps = 34/270 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG V Y G+ VAVK +K D Q + E ++ L H ++++
Sbjct 200 IGEGEFGAVLQGEY------LGQKVAVKNIKCDVTAQ---AFLDETAVMTKLQHRNLVRL 250
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
G G L +VME+V G+L ++L R + +QLL FA + EGM YL ++
Sbjct 251 LGVILHHG---LYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKL 307
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDLAARN+L+ D + K+ DFGLAKA E + + PV W APE LK +F
Sbjct 308 VHRDLAARNILVSEDLVAKVSDFGLAKA-----ELRKGLDSSRLPVKWTAPEALKNGRFS 362
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SDVWSFGV L+E+ ++ ++P K M++ ++E +E+G R+ PD
Sbjct 363 SKSDVWSFGVLLWEVFSY---GRAPYPK-----------MSLKEVSEAVEKGYRMEPPDS 408
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
CP V+ LM +CWE E S RP F ++ L
Sbjct 409 CPGPVHTLMGSCWEAEPSRRPPFRKIVEKL 438
Score = 97.1 bits (240), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 75/222 (34%), Positives = 110/222 (50%), Gaps = 15/222 (7%)
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAW 710
A AF + ++M+++ H +L + GV + I V E+V G L +LR R R V +
Sbjct 229 AQAFLDETAVMTKLQHRNLVRLLGVILHHGLYI-VMEHVSKGNLVNFLRTRGRALVSTSQ 287
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ A +A + YLE+K LVH ++ RNIL++ +A K+SD G+ L +
Sbjct 288 LLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVA-------KVSDFGLAKAELRKG 340
Query 771 ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
R+P W APE L G S+ D W FG L E+ G AP S E +
Sbjct 341 LDSSRLPVKWTAPEALKNG--RFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVE 398
Query 829 RQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ +R+ P SCP + TL C EP++RP FR I+ L R
Sbjct 399 KGYRMEPPDSCPGPVHTLMGSCWEAEPSRRPPFRKIVEKLGR 440
>sp|Q9QVP9|FAK2_MOUSE Protein-tyrosine kinase 2-beta OS=Mus musculus
OX=10090 GN=Ptk2b PE=1 SV=2
Length=1009
Score = 166 bits (420), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 102/279 (37%), Positives = 153/279 (55%), Gaps = 28/279 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LGEG FG+V Y + G VAVK K DC ++ + E I++ L H HI+
Sbjct 429 RILGEGFFGEVYEGVYT-NHKGEKINVAVKTCKKDCTQDNKEKFMSEAVIMKNLDHPHIV 487
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQH 1018
K G E E+ ++ME P G L YL R+ S+ + L+L+ QIC+ MAYL + +
Sbjct 488 KLIGIIE---EEPTWIIMELYPYGELGHYLERNKNSLKVPTLVLYTLQICKAMAYLESIN 544
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRD+A RN+L+ + VK+GDFGL++ + E +YY+ P+ W +PE + +F
Sbjct 545 CVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKA-SVTRLPIKWMSPESINFRRF 602
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE---LIGIAQGQMTVLRLTELLERGERLP 1135
ASDVW F V ++E+L S P +LE +IG+ LE+G+RLP
Sbjct 603 TTASDVWMFAVCMWEIL----SFGKQPFFWLENKDVIGV-------------LEKGDRLP 645
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+P+ CP +Y LM CW+ + S RP F L+ L +++
Sbjct 646 KPELCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDIYQ 684
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 76/296 (26%), Positives = 127/296 (43%), Gaps = 43/296 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V ++E+ LG+G VYEG V +G+++ V +K
Sbjct 420 VAREEVVLNRILGEGFFGEVYEG---------------------VYTNHKGEKINVAVKT 458
Query 644 LDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
D F A +M + H H+ + G+ P I + E +G L +L R
Sbjct 459 CKKDCTQDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWI-IMELYPYGELGHYLERN 517
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ + + ++ Q+ A++YLE+ N VH ++ RNIL+A + +KL D
Sbjct 518 KNSLKVPTLVLYTLQICKAMAYLESINCVHRDIAVRNILVA-------SPECVKLGD--F 568
Query 763 GLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
GL +E V R+P W++PE + +TA D W F + EI G+ P
Sbjct 569 GLSRYIEDEDYYKASVTRLPIKWMSPESI--NFRRFTTASDVWMFAVCMWEILSFGKQPF 626
Query 816 QSRSPSEKEHFYQRQHRLPEPSC--PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ ++ RLP+P P L TL ++C Y+P+ RP F ++ L+ +
Sbjct 627 FWLENKDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDI 682
>sp|P42683|LCK_CHICK Proto-oncogene tyrosine-protein kinase LCK
OS=Gallus gallus OX=9031 GN=LCK PE=2 SV=2
Length=508
Score = 160 bits (406), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 98/286 (34%), Positives = 147/286 (51%), Gaps = 29/286 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
LK + LG G FG+V + Y+ VA+K LK G S + E ++++ L H
Sbjct 244 LKLVEKLGAGQFGEVWMGFYNGHTK-----VAIKNLKQ--GSMSPSAFLAEANLMKNLQH 296
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAY 1013
+++ ++ + ++ EY+ GSL D+L + + +LL A QI EGMA+
Sbjct 297 PRLVRLYAVV---TKEPIYIITEYMEKGSLVDFLKTSEGIKLSINKLLDMAAQIAEGMAF 353
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ A++YIHRDL A N+L+ KI DFGLA+ + + Y RE P+ W APE +
Sbjct 354 IEAKNYIHRDLRAANILVSEALCCKIADFGLARLIEDNE--YTAREGAKFPIKWTAPEAI 411
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
F SDVWSFG+ L E++T+ I MT + + LERG R
Sbjct 412 NYGTFTIKSDVWSFGILLTEIVTYGR--------------IPYPGMTNPEVIQNLERGYR 457
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+PD CP E+Y LM CW+ + RPTFE + +L+ +GQ
Sbjct 458 MPQPDNCPQELYELMMQCWKEQPEERPTFEYMKSVLEDFFTATEGQ 503
Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 69/226 (31%), Positives = 111/226 (49%), Gaps = 25/226 (11%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
AF A+LM + H L ++ V + P I +TEY+E G L +L+ G K++
Sbjct 283 AFLAEANLMKNLQHPRLVRLYAVVTKEPIYI-ITEYMEKGSLVDFLKTSEGIKLSINKLL 341
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----- 767
+A Q+A ++++E KN +H ++ NIL++ + K++D GL L
Sbjct 342 DMAAQIAEGMAFIEAKNYIHRDLRAANILVSE-------ALCCKIAD--FGLARLIEDNE 392
Query 768 --SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
+RE I W APE + G ++ + D W FG L EI G P + E
Sbjct 393 YTAREGAKFPIKWTAPEAINYGTFTIKS--DVWSFGILLTEIVTYGRIPYPGMTNPEVIQ 450
Query 826 FYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSF---RTILRDL 866
+R +R+P+P +CPQ L L QC +P +RP+F +++L D
Sbjct 451 NLERGYRMPQPDNCPQELYELMMQCWKEQPEERPTFEYMKSVLEDF 496
>sp|Q62956|ERBB4_RAT Receptor tyrosine-protein kinase erbB-4 OS=Rattus
norvegicus OX=10116 GN=Erbb4 PE=1 SV=3
Length=1308
Score = 166 bits (421), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 107/305 (35%), Positives = 159/305 (52%), Gaps = 21/305 (7%)
Query 864 RDLTRLQPHNLADVLTVNPDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922
R L R L + LT + +P + + + LK+++ LG G FG V + P +
Sbjct 684 RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGET 743
Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982
VA+K L GP+ + E I+ ++ H H+++ G C ++QLV + +P
Sbjct 744 VKIPVAIKILNETTGPKANVEFMDEALIMASVDHPHLVRLLGVCL---SPTIQLVTQLMP 800
Query 983 LGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040
G L +Y+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI
Sbjct 801 HGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKIT 860
Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100
DFGLA+ + EG E + G P+ W A EC+ KF + SDVWS+GVT++EL+T
Sbjct 861 DFGLARLL-EGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMT---- 915
Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
G + + +LLE+GERLP+P C +VY +M CW +A RP
Sbjct 916 ----------FGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYIVMVKCWMIDADSRP 965
Query 1161 TFENL 1165
F+ L
Sbjct 966 KFKEL 970
Score = 77.8 bits (190), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 70/302 (23%), Positives = 129/302 (43%), Gaps = 39/302 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+Q + + E+ ++ LG G VY+G EG E +P
Sbjct 706 NQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEG-----------ETVKIP------- 747
Query 637 LRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K+L+ + A + F + A +M+ V H HL + GVC+ P +VT+ + HG L
Sbjct 748 --VAIKILNETTGPKANVEFMDEALIMASVDHPHLVRLLGVCL-SPTIQLVTQLMPHGCL 804
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
++ + ++ + Q+A + YLE + LVH ++ RN+L+ + +
Sbjct 805 LEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVK-------SPNHV 857
Query 756 KLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
K++D G+ L +E + I W+A EC+ + D W +G T+ E+
Sbjct 858 KITDFGLARLLEGDEKEYNADGGKMPIKWMALECI--HYRKFTHQSDVWSYGVTIWELMT 915
Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLT 867
G P E ++ RLP+P + + +C + RP F+ + + +
Sbjct 916 FGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYIVMVKCWMIDADSRPKFKELAAEFS 975
Query 868 RL 869
R+
Sbjct 976 RM 977
>sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens
OX=9606 GN=PTK2 PE=1 SV=2
Length=1052
Score = 166 bits (419), Expect = 3e-40, Method: Compositional matrix adjust.
Identities = 104/282 (37%), Positives = 148/282 (52%), Gaps = 24/282 (9%)
Query 901 RDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
R +GEG FG V Y P N VA+K K R + QE +R H HI
Sbjct 426 RCIGEGQFGDVHQGIYMSPENPALA--VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 483
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+K G E + ++ME LG LR +L ++S+ LA L+L+A Q+ +AYL ++
Sbjct 484 VKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK 540
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
++HRD+AARNVL+ ++ VK+GDFGL++ + E YY+ + G P+ W APE + +
Sbjct 541 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYM-EDSTYYKASK-GKLPIKWMAPESINFRR 598
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F ASDVW FGV ++E+L H K ++IG +E GERLP P
Sbjct 599 FTSASDVWMFGVCMWEILMH-GVKPFQGVKNNDVIG-------------RIENGERLPMP 644
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
CP +Y LM CW + S RP F L L T+ E+ + Q
Sbjct 645 PNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQ 686
Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 64/224 (29%), Positives = 107/224 (48%), Gaps = 21/224 (9%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F + A M Q H H+ + GV P I + E G L +L+ + + +A ++
Sbjct 468 FLQEALTMRQFDHPHIVKLIGVITENPVWI-IMELCTLGELRSFLQVRKYSLDLASLILY 526
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
A QL++AL+YLE+K VH ++ RN+L++ ++ +KL D GL +
Sbjct 527 AYQLSTALAYLESKRFVHRDIAARNVLVS-------SNDCVKLGD--FGLSRYMEDSTYY 577
Query 775 R-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
+ I W+APE + ++A D W FG + EI G P Q ++
Sbjct 578 KASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 635
Query 828 QRQHRLP-EPSC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ RLP P+C P L +L ++C Y+P++RP F + L+ +
Sbjct 636 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679
>sp|P41239|CSK_CHICK Tyrosine-protein kinase CSK OS=Gallus gallus
OX=9031 GN=CSK PE=2 SV=1
Length=450
Score = 158 bits (400), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 99/282 (35%), Positives = 145/282 (51%), Gaps = 33/282 (12%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
LK ++ +G+G FG V L D G VAVK +K D Q + E ++ L H
Sbjct 195 LKLLQIIGKGEFGDVML------GDYRGNKVAVKCIKNDATAQ---AFLAEASVMTQLRH 245
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAY 1013
++++ G ++ + L +V EY+ GSL DYL R +G LL F+ +CE M Y
Sbjct 246 SNLVQLLGVIVEE-KSGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEY 304
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
L A +++HRDLAARNVL+ D + K+ DFGL K E ++ G PV W APE L
Sbjct 305 LEANNFVHRDLAARNVLVSEDNIAKVSDFGLTK------EASSTQDTGKLPVKWTAPEAL 358
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+E KF SDVWSFG+ L+E+ + + ++ + + +E+G +
Sbjct 359 REKKFSTKSDVWSFGILLWEIYSFGR--------------VPYPRIPLKDVVPRVEKGYK 404
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+ PD CP VY +MK CW + RP+F L L + EK
Sbjct 405 MDPPDGCPAIVYEVMKKCWTLDPGHRPSFHQLREQLVHIKEK 446
Score = 84.0 bits (206), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 67/228 (29%), Positives = 107/228 (47%), Gaps = 14/228 (6%)
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLR-RERGHVPMA 709
A AF AS+M+Q+ H++L + GV V + +VTEY+ G L +LR R R +
Sbjct 230 AQAFLAEASVMTQLRHSNLVQLLGVIVEEKSGLYIVTEYMAKGSLVDYLRSRGRSVLGGD 289
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+ + + A+ YLE N VH ++ RN+L++ +A K+SD G+ A S
Sbjct 290 CLLKFSLDVCEAMEYLEANNFVHRDLAARNVLVSEDNIA-------KVSDFGLTKEASST 342
Query 770 EERVER-IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
++ + + W APE L ST D W FG L EI G P + +
Sbjct 343 QDTGKLPVKWTAPEALR--EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVE 400
Query 829 RQHRLPEPS-CPQLA-TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
+ +++ P CP + + +C T +P RPSF + L ++ L
Sbjct 401 KGYKMDPPDGCPAIVYEVMKKCWTLDPGHRPSFHQLREQLVHIKEKEL 448
>sp|Q01621|LCK_RAT Proto-oncogene tyrosine-protein kinase LCK
OS=Rattus norvegicus OX=10116 GN=Lck PE=1 SV=3
Length=509
Score = 159 bits (403), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 100/289 (35%), Positives = 147/289 (51%), Gaps = 29/289 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+ LK + LG G FG+V + Y+ VAVK+LK G + E ++++
Sbjct 242 RETLKLVERLGAGQFGEVWMGYYNGHTK-----VAVKSLKQ--GSMSPDAFLAEANLMKQ 294
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEG 1010
L H +++ ++ + ++ EY+ GSL D+L S + + +LL A QI EG
Sbjct 295 LQHPRLVRLYAVVT---QEPIYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQIAEG 351
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
MA++ Q+YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W AP
Sbjct 352 MAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKWTAP 409
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E + F SDVWSFG+ L E++TH I MT + + LE+
Sbjct 410 EAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQNLEK 455
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
G R+ RPD CP E+YHLM CW+ RPTF+ L +L +GQ
Sbjct 456 GYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLDDFFTATEGQ 504
Score = 77.8 bits (190), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 66/226 (29%), Positives = 108/226 (48%), Gaps = 25/226 (11%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
AF A+LM Q+ H L ++ V + P I +TEY+E+G L +L+ G K++
Sbjct 284 AFLAEANLMKQLQHPRLVRLYAVVTQEPIYI-ITEYMENGSLVDFLKTPSGIKLNVNKLL 342
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----- 767
+A Q+A ++++E +N +H ++ NIL++ + K++D GL L
Sbjct 343 DMAAQIAEGMAFIEEQNYIHRDLRAANILVS-------DTLSCKIAD--FGLARLIEDNE 393
Query 768 --SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
+RE I W APE + G ++ + D W FG L EI G P + E
Sbjct 394 YTAREGAKFPIKWTAPEAINYGTFTIKS--DVWSFGILLTEIVTHGRIPYPGMTNPEVIQ 451
Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF---RTILRDL 866
++ +R+ P +CP +L L C P RP+F R++L D
Sbjct 452 NLEKGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLDDF 497
>sp|P34152|FAK1_MOUSE Focal adhesion kinase 1 OS=Mus musculus
OX=10090 GN=Ptk2 PE=1 SV=4
Length=1052
Score = 165 bits (417), Expect = 5e-40, Method: Compositional matrix adjust.
Identities = 104/282 (37%), Positives = 148/282 (52%), Gaps = 24/282 (9%)
Query 901 RDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
R +GEG FG V Y P N VA+K K R + QE +R H HI
Sbjct 426 RCIGEGQFGDVHQGVYLSPENPALA--VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 483
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+K G E + ++ME LG LR +L ++S+ LA L+L+A Q+ +AYL ++
Sbjct 484 VKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK 540
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
++HRD+AARNVL+ ++ VK+GDFGL++ + E YY+ + G P+ W APE + +
Sbjct 541 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYM-EDSTYYKASK-GKLPIKWMAPESINFRR 598
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F ASDVW FGV ++E+L H K ++IG +E GERLP P
Sbjct 599 FTSASDVWMFGVCMWEILMH-GVKPFQGVKNNDVIG-------------RIENGERLPMP 644
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
CP +Y LM CW + S RP F L L T+ E+ + Q
Sbjct 645 PNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQ 686
Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 64/224 (29%), Positives = 107/224 (48%), Gaps = 21/224 (9%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F + A M Q H H+ + GV P I + E G L +L+ + + +A ++
Sbjct 468 FLQEALTMRQFDHPHIVKLIGVITENPVWI-IMELCTLGELRSFLQVRKYSLDLASLILY 526
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
A QL++AL+YLE+K VH ++ RN+L++ ++ +KL D GL +
Sbjct 527 AYQLSTALAYLESKRFVHRDIAARNVLVS-------SNDCVKLGD--FGLSRYMEDSTYY 577
Query 775 R-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
+ I W+APE + ++A D W FG + EI G P Q ++
Sbjct 578 KASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 635
Query 828 QRQHRLP-EPSC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ RLP P+C P L +L ++C Y+P++RP F + L+ +
Sbjct 636 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679
>sp|P06239|LCK_HUMAN Tyrosine-protein kinase Lck OS=Homo sapiens
OX=9606 GN=LCK PE=1 SV=6
Length=509
Score = 159 bits (402), Expect = 5e-40, Method: Compositional matrix adjust.
Identities = 99/289 (34%), Positives = 149/289 (52%), Gaps = 29/289 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+ LK + LG G FG+V + Y+ VAVK+LK G + E ++++
Sbjct 242 RETLKLVERLGAGQFGEVWMGYYNGHTK-----VAVKSLKQ--GSMSPDAFLAEANLMKQ 294
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEG 1010
L H+ +++ ++ + ++ EY+ GSL D+L S + + +LL A QI EG
Sbjct 295 LQHQRLVRLYAVVT---QEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEG 351
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
MA++ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W AP
Sbjct 352 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKWTAP 409
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E + F SDVWSFG+ L E++TH I MT + + LER
Sbjct 410 EAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQNLER 455
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
G R+ RPD CP E+Y LM+ CW+ RPTF+ L +L+ +GQ
Sbjct 456 GYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATEGQ 504
Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 67/226 (30%), Positives = 108/226 (48%), Gaps = 25/226 (11%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
AF A+LM Q+ H L ++ V + P I +TEY+E+G L +L+ G K++
Sbjct 284 AFLAEANLMKQLQHQRLVRLYAVVTQEPIYI-ITEYMENGSLVDFLKTPSGIKLTINKLL 342
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----- 767
+A Q+A ++++E +N +H ++ NIL++ + K++D GL L
Sbjct 343 DMAAQIAEGMAFIEERNYIHRDLRAANILVS-------DTLSCKIAD--FGLARLIEDNE 393
Query 768 --SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
+RE I W APE + G ++ + D W FG L EI G P + E
Sbjct 394 YTAREGAKFPIKWTAPEAINYGTFTIKS--DVWSFGILLTEIVTHGRIPYPGMTNPEVIQ 451
Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF---RTILRDL 866
+R +R+ P +CP +L L C P RP+F R++L D
Sbjct 452 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 497
>sp|O35346|FAK1_RAT Focal adhesion kinase 1 OS=Rattus norvegicus
OX=10116 GN=Ptk2 PE=1 SV=1
Length=1055
Score = 165 bits (417), Expect = 6e-40, Method: Compositional matrix adjust.
Identities = 104/282 (37%), Positives = 148/282 (52%), Gaps = 24/282 (9%)
Query 901 RDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
R +GEG FG V Y P N VA+K K R + QE +R H HI
Sbjct 426 RCIGEGQFGDVHQGVYLSPENPALA--VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 483
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+K G E + ++ME LG LR +L ++S+ LA L+L+A Q+ +AYL ++
Sbjct 484 VKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK 540
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
++HRD+AARNVL+ ++ VK+GDFGL++ + E YY+ + G P+ W APE + +
Sbjct 541 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYM-EDSTYYKASK-GKLPIKWMAPESINFRR 598
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F ASDVW FGV ++E+L H K ++IG +E GERLP P
Sbjct 599 FTSASDVWMFGVCMWEILMH-GVKPFQGVKNNDVIG-------------RIENGERLPMP 644
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
CP +Y LM CW + S RP F L L T+ E+ + Q
Sbjct 645 PNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQ 686
Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 64/224 (29%), Positives = 107/224 (48%), Gaps = 21/224 (9%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F + A M Q H H+ + GV P I + E G L +L+ + + +A ++
Sbjct 468 FLQEALTMRQFDHPHIVKLIGVITENPVWI-IMELCTLGELRSFLQVRKYSLDLASLILY 526
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
A QL++AL+YLE+K VH ++ RN+L++ ++ +KL D GL +
Sbjct 527 AYQLSTALAYLESKRFVHRDIAARNVLVS-------SNDCVKLGD--FGLSRYMEDSTYY 577
Query 775 R-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
+ I W+APE + ++A D W FG + EI G P Q ++
Sbjct 578 KASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 635
Query 828 QRQHRLP-EPSC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ RLP P+C P L +L ++C Y+P++RP F + L+ +
Sbjct 636 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679
>sp|P42685|FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo sapiens
OX=9606 GN=FRK PE=1 SV=1
Length=505
Score = 159 bits (401), Expect = 7e-40, Method: Compositional matrix adjust.
Identities = 97/273 (36%), Positives = 145/273 (53%), Gaps = 27/273 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
++ ++ LG G FG+V ++ T VAVK LK G + + +E I++ L H
Sbjct 234 IQLLKRLGSGQFGEVWEGLWNNTTP-----VAVKTLKP--GSMDPNDFLREAQIMKNLRH 286
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAY 1013
+I+ C E + ++ E + GSL++YL + I L Q + A Q+ GMAY
Sbjct 287 PKLIQLYAVC--TLEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAY 344
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPEC 1072
L +++YIHRDLAARNVL+ + K+ DFGLA+ + + Y R + PV W APE
Sbjct 345 LESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEA 404
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
++ KF SDVWSFG+ LYE++T+ S MT ++ ++L +
Sbjct 405 IRSNKFSIKSDVWSFGILLYEIITYGKMPYSG--------------MTGAQVIQMLAQNY 450
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
RLP+P CP + Y++M CW E RPTFE L
Sbjct 451 RLPQPSNCPQQFYNIMLECWNAEPKERPTFETL 483
Score = 104 bits (259), Expect = 8e-22, Method: Compositional matrix adjust.
Identities = 81/296 (27%), Positives = 133/296 (45%), Gaps = 43/296 (15%)
Query 579 LSFHRVDQKEITQ-----LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
LS+ VDQ EI + L LG G V+EG ++ P
Sbjct 219 LSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGL-------------WNNTTP------- 258
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
V +K L P D F A +M + H L ++ VC ++TE + HG
Sbjct 259 -----VAVKTLKPGSMDPN-DFLREAQIMKNLRHPKLIQLYAVCTLEDPIYIITELMRHG 312
Query 694 PLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE--- 749
L +L+ + G + + ++ +A Q+AS ++YLE++N +H ++ RN+L+ + +
Sbjct 313 SLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVAD 372
Query 750 -GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
G + K+ + + SR E + W APE + +N S D W FG L EI
Sbjct 373 FGLARVFKVDNEDI---YESRHEIKLPVKWTAPEAIR--SNKFSIKSDVWSFGILLYEII 427
Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862
G+ P + ++ + +RLP+PS CP Q + +C EP +RP+F T+
Sbjct 428 TYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERPTFETL 483
>sp|Q922K9|FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus musculus
OX=10090 GN=Frk PE=1 SV=3
Length=512
Score = 159 bits (402), Expect = 7e-40, Method: Compositional matrix adjust.
Identities = 98/284 (35%), Positives = 147/284 (52%), Gaps = 27/284 (10%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
+D + ++ ++ LG G FG+V ++ T VAVK LK G + +
Sbjct 230 TADQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTP-----VAVKTLKP--GSMDPNDFL 282
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLL 1002
+E I+++L H +I+ C E + ++ E + GSL++YL I L Q +
Sbjct 283 REAQIMKSLRHPKLIQLYAVC--TLEDPIYIITELMRHGSLQEYLQNDGGSKIHLIQQVD 340
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDG 1061
A Q+ GMAYL +Q+YIHRDLAARNVL+ + K+ DFGLA+ + + Y + +
Sbjct 341 MAAQVASGMAYLESQNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESKHEI 400
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
PV W APE ++ KF SDVWSFG+ LYE++T+ S MT
Sbjct 401 KLPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGKMPYSG--------------MTG 446
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
++ ++L + RLP+P CP + Y +M CW E RPTFE L
Sbjct 447 AQVIQMLSQNYRLPQPSNCPQQFYSIMLECWNVEPKQRPTFETL 490
Score = 102 bits (255), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 80/304 (26%), Positives = 133/304 (44%), Gaps = 46/304 (15%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P L+ +D+ I L LG G V+EG ++ P
Sbjct 222 TPFDLSYKTADQWEIDRNSIQLLKRLGSGQFGEVWEGL-------------WNNTTP--- 265
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
V +K L P D F A +M + H L ++ VC ++TE
Sbjct 266 ---------VAVKTLKPGSMDPN-DFLREAQIMKSLRHPKLIQLYAVCTLEDPIYIITEL 315
Query 690 VEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ HG L +L+ + G + + ++ +A Q+AS ++YLE++N +H ++ RN+L+
Sbjct 316 MRHGSLQEYLQNDGGSKIHLIQQVDMAAQVASGMAYLESQNYIHRDLAARNVLV------ 369
Query 749 EGTSPFIKLSDPGVG-LGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGF 800
G K++D G+ + + E+ E + W APE + N S D W F
Sbjct 370 -GEHNIYKVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIR--TNKFSIKSDVWSF 426
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPS 858
G L EI G+ P + ++ + +RLP+PS CP Q ++ +C EP QRP+
Sbjct 427 GILLYEIITYGKMPYSGMTGAQVIQMLSQNYRLPQPSNCPQQFYSIMLECWNVEPKQRPT 486
Query 859 FRTI 862
F T+
Sbjct 487 FETL 490
>sp|P42690|SRK4_SPOLA Tyrosine-protein kinase isoform SRK4 OS=Spongilla
lacustris OX=6055 GN=SRK1 PE=2 SV=1
Length=506
Score = 159 bits (401), Expect = 7e-40, Method: Compositional matrix adjust.
Identities = 111/333 (33%), Positives = 168/333 (50%), Gaps = 44/333 (13%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP---------------ASDPTVFHK 894
TY T+R +F++I ++L AD L VN P A++ K
Sbjct 180 TYFVTRRLTFQSI-QELVAYYTQQ-ADGLCVNLKGPCMVMEKPQTAGLSKQANEEWEIEK 237
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+ +K +R LG G FG+V ++ T VAVK LK G + +E I++ L
Sbjct 238 KQIKLLRGLGAGQFGEVWEGLWNGTTS-----VAVKTLKP--GTMSIEEFLEEASIMKQL 290
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMA 1012
H +I+ C E+ + +V E + GSL +YL S+ L L+ Q+ GM+
Sbjct 291 RHPKLIQLYAVCTK--EEPIYIVTELMKHGSLLEYLRGDGRSLKLPDLVDMCSQVASGMS 348
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
YL Q+YIHRDLAARN+L+ ++ K+ DFGLA+ + E E Y + P+ W APE
Sbjct 349 YLEQQNYIHRDLAARNILVGEHKICKVADFGLARVIDE--EIYEAKLGAKFPIKWTAPEA 406
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+F SDVWSFG+ LYE++T+ + P MT ++ E +++
Sbjct 407 AMYSRFTIKSDVWSFGIVLYEVITY---GRFPYPG-----------MTNAQVLEQIQQSY 452
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
R+PRP CP ++Y +M +CW + + RPTFE L
Sbjct 453 RMPRPMGCPEKLYAIMMDCWREDPASRPTFETL 485
Score = 100 bits (248), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 103/405 (25%), Positives = 165/405 (41%), Gaps = 74/405 (18%)
Query 469 GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRE 528
G +LI S + P L+V R+R + I++ + +F S++E
Sbjct 144 GSFLIRDSDTTPGDFSLSVRDID---------RVRHYRIKKLENGTYFVTRRLTFQSIQE 194
Query 529 LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHR--VDQ 586
L A +A C +L+ C+ P+T LS+ + +++
Sbjct 195 LVAYYTQ---QADGLCVNLKGPCM--------------VMEKPQTAGLSKQANEEWEIEK 237
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
K+I L LG G V+EG S V +K L P
Sbjct 238 KQIKLLRGLGAGQFGEVWEGLWNGTTS-------------------------VAVKTLKP 272
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
I F E AS+M Q+ H L ++ VC + +VTE ++HG L +LR + +
Sbjct 273 GTMSIE-EFLEEASIMKQLRHPKLIQLYAVCTKEEPIYIVTELMKHGSLLEYLRGDGRSL 331
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ + + Q+AS +SYLE +N +H ++ RNIL+ G K++D GL
Sbjct 332 KLPDLVDMCSQVASGMSYLEQQNYIHRDLAARNILV-------GEHKICKVAD--FGLAR 382
Query 767 LSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ EE E I W APE + + D W FG L E+ G P +
Sbjct 383 VIDEEIYEAKLGAKFPIKWTAPEA--AMYSRFTIKSDVWSFGIVLYEVITYGRFPYPGMT 440
Query 820 PSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
++ Q+ +R+P P CP+ L + C +P RP+F T+
Sbjct 441 NAQVLEQIQQSYRMPRPMGCPEKLYAIMMDCWREDPASRPTFETL 485
>sp|P08631|HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo sapiens
OX=9606 GN=HCK PE=1 SV=5
Length=526
Score = 159 bits (401), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 94/286 (33%), Positives = 145/286 (51%), Gaps = 29/286 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
LK + LG G FG+V + Y+ VAVK +K G + E ++++TL H
Sbjct 262 LKLEKKLGAGQFGEVWMATYNKHTK-----VAVKTMKP--GSMSVEAFLAEANVMKTLQH 314
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAY 1013
+ ++K + + ++ E++ GSL D+L L +L+ F+ QI EGMA+
Sbjct 315 DKLVKLHAVVTKE---PIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAF 371
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W APE +
Sbjct 372 IEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAI 429
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
F SDVWSFG+ L E++T+ I M+ + LERG R
Sbjct 430 NFGSFTIKSDVWSFGILLMEIVTYGR--------------IPYPGMSNPEVIRALERGYR 475
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+PRP+ CP E+Y++M CW+ RPTFE + +L + + Q
Sbjct 476 MPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ 521
Score = 88.2 bits (217), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 65/234 (28%), Positives = 110/234 (47%), Gaps = 21/234 (9%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K + P + AF A++M + H L +H V + P I +TE++ G L
Sbjct 286 KVAVKTMKPGSMSVE-AFLAEANVMKTLQHDKLVKLHAVVTKEPIYI-ITEFMAKGSLLD 343
Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ + G P+ + + Q+A ++++E +N +H ++ NIL++ S K
Sbjct 344 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-------ASLVCK 396
Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
++D G+ + E R I W APE + G S + D W FG L+EI
Sbjct 397 IADFGLAR-VIEDNEYTAREGAKFPIKWTAPEAINFG--SFTIKSDVWSFGILLMEIVTY 453
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTI 862
G P S E +R +R+P P +CP +L + +C P +RP+F I
Sbjct 454 GRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYI 507
>sp|Q24592|JAK_DROME Tyrosine-protein kinase hopscotch OS=Drosophila
melanogaster OX=7227 GN=hop PE=1 SV=2
Length=1177
Score = 164 bits (415), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 161/574 (28%), Positives = 252/574 (44%), Gaps = 69/574 (12%)
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+++ V +K+L + + F+ A S + ++G+ + P MV EY +GP
Sbjct 608 KDVSVTMKMLKSDGN--FMEFFRLAQTWSLIQSPQFLKLYGLTLADPYT-MVMEYSRYGP 664
Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
L+ +L +V + + + L + YLE+ ++H + N+ + +
Sbjct 665 LNKFLH-SMPNVTLHCLLDLMHGLVRGMHYLEDNKIIHNYIRCSNLYVTKYD-PNSYVLD 722
Query 755 IKLSDPGVGLGALSREERVERIPWLAPECLPG-GANSLSTAMDKWGFGATLLEI---CFD 810
K+SDPG R R PW+ + A W F T+ EI C +
Sbjct 723 AKISDPGY-----PRPYRESDSPWIPVKYYRNLQAAKTDQFAQLWAFATTIYEIFSRCKE 777
Query 811 GEAPL-QSRSPSEKEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ L Q + +K L + CP + + + T+R S I L
Sbjct 778 DLSTLRQEQLLRQKNLDGNILKMLDQDICPAPIFETIMDGWSDDETKRFSHHDIFSRLNT 837
Query 869 LQPHNLADVL-------------TVNPDS-------PASD-----PTVFHKRYLKKIRDL 903
++ L + + TV S P S+ P R + + ++
Sbjct 838 IKAEILPNYMPPPEIATNGTGDETVIDRSDIPFLPFPRSNMLMVIPLTSECRVIYNMENM 897
Query 904 -GEGHFGKVSLYCYDPTN-DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
G GH+G V + + D E VA+K L Q + + +EI I+RTL H +I+K
Sbjct 898 IGRGHYGTVYKGHLEFNDKDQPREQVAIKMLNT---MQVSTDFHREIGIMRTLSHPNIVK 954
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019
+K EKS ++MEY+ GS YL + L +L+ FA I GM YL
Sbjct 955 FKYW----AEKSHCIIMEYLQSGSFDIYLRFTAPNLNNPRLVSFALDIANGMKYLSDMGL 1010
Query 1020 IHRDLAARNVLLDND---RLVKIGDFGLAK-AVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
IHRDLAARN+L+D++ VKI DFGLA+ A +G YY + D P+ WY+PE +
Sbjct 1011 IHRDLAARNILVDHNGDGDCVKISDFGLAQFANSDG--YYYAKSKRDIPIRWYSPEAIST 1068
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+F SDVWS+GVTL+E+ + + L+ I Q L L+ GERL
Sbjct 1069 CRFSSYSDVWSYGVTLFEMFSRGEEPN--------LVPIQTSQEDFL---NRLQSGERLN 1117
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
RP CP +Y LM+ CW RP+F ++ I+
Sbjct 1118 RPASCPDFIYDLMQLCWHATPRSRPSFATIVDII 1151
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 73/285 (26%), Positives = 121/285 (42%), Gaps = 40/285 (14%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
+G+G VY+G L P E +V +K+L+ ++
Sbjct 898 IGRGHYGTVYKGHLEFNDKDQPRE-------------------QVAIKMLNTMQ--VSTD 936
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F+ +M +SH ++ + + ++ EY++ G D++LR ++ +
Sbjct 937 FHREIGIMRTLSHPNIVKFKYWAEKS--HCIIMEYLQSGSFDIYLRFTAPNLNNPRLVSF 994
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS------ 768
A +A+ + YL + L+H ++ RNIL+ G +K+SD G+ A S
Sbjct 995 ALDIANGMKYLSDMGLIHRDLAARNILVDH----NGDGDCVKISDFGLAQFANSDGYYYA 1050
Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
+ +R I W +PE + S+ D W +G TL E+ GE P + +E F
Sbjct 1051 KSKRDIPIRWYSPEAI--STCRFSSYSDVWSYGVTLFEMFSRGEEPNLVPIQTSQEDFLN 1108
Query 829 RQH---RLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTR 868
R RL P SCP + L C P RPSF TI+ +TR
Sbjct 1109 RLQSGERLNRPASCPDFIYDLMQLCWHATPRSRPSFATIVDIITR 1153
Score = 45.8 bits (107), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 51/206 (25%), Positives = 84/206 (41%), Gaps = 31/206 (15%)
Query 976 LVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL- 1031
+VMEY G L +L HS + L LL + GM YL IH + N+ +
Sbjct 655 MVMEYSRYGPLNKFL--HSMPNVTLHCLLDLMHGLVRGMHYLEDNKIIHNYIRCSNLYVT 712
Query 1032 --DNDRLV---KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
D + V KI D G + YR + PV +Y L+ K + +W+
Sbjct 713 KYDPNSYVLDAKISDPGYPRP-------YRESDSPWIPVKYY--RNLQAAKTDQFAQLWA 763
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
F T+YE+ + C +L + Q Q+ LR L ++ D CP ++
Sbjct 764 FATTIYEIFSRCKE---------DLSTLRQEQL--LRQKNLDGNILKMLDQDICPAPIFE 812
Query 1147 LMKNCWETEASFRPTFENLIPILKTV 1172
+ + W + + R + ++ L T+
Sbjct 813 TIMDGWSDDETKRFSHHDIFSRLNTI 838
>sp|Q03142|FGFR4_MOUSE Fibroblast growth factor receptor 4 OS=Mus
musculus OX=10090 GN=Fgfr4 PE=1 SV=3
Length=799
Score = 162 bits (410), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 112/322 (35%), Positives = 160/322 (50%), Gaps = 42/322 (13%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADC 936
VN D P F + L + LGEG FG+V + DP+ VAVK LK +
Sbjct 447 VNLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPSRPDQTSTVAVKMLKDNA 506
Query 937 GPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----- 990
+ + E+++++ + H++II G C +G L +++E G+LR++L
Sbjct 507 SDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEG--PLYVIVECAAKGNLREFLRARRP 564
Query 991 ---------PRHSIG---LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
PR S G L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++K
Sbjct 565 PGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDDVMK 624
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
I DFGLA+ V +YY+ +G PV W APE L + + + SDVWSF + L+E+ T
Sbjct 625 IADFGLARGV-HHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFEILLWEIFT-- 681
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
L G + V L LL G R+ RP CP E+Y LM+ CW S
Sbjct 682 ------------LGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRECWHAAPSQ 729
Query 1159 RPTFENLI----PILKTVHEKY 1176
RPTF+ L+ +L V E+Y
Sbjct 730 RPTFKQLVEALDKVLLAVSEEY 751
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 70/282 (25%), Positives = 120/282 (43%), Gaps = 38/282 (13%)
Query 635 QELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
Q V +K+L + S D+A E + H ++ + GVC + ++ E
Sbjct 493 QTSTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAK 552
Query 693 GPLDVWLRRER-------------GHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCG 737
G L +LR R P+++ +V A Q+A + YLE++ +H ++
Sbjct 553 GNLREFLRARRPPGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDLAA 612
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSL 791
RN+L+ +K++D G+ G ++ R+P W+APE L +
Sbjct 613 RNVLVTE-------DDVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTH 665
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCL 849
+ D W F L EI G +P E + HR+ P+CP +L L +C
Sbjct 666 QS--DVWSFEILLWEIFTLGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRECW 723
Query 850 TYEPTQRPSFRTILRDLTR----LQPHNLADVLTVNPDSPAS 887
P+QRP+F+ ++ L + + L LT P SP++
Sbjct 724 HAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPFSPSN 765
>sp|P22455|FGFR4_HUMAN Fibroblast growth factor receptor 4 OS=Homo
sapiens OX=9606 GN=FGFR4 PE=1 SV=2
Length=802
Score = 162 bits (410), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 109/310 (35%), Positives = 156/310 (50%), Gaps = 42/310 (14%)
Query 892 FHKRYLKKIRDLGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
F + L + LGEG FG+V + DP VAVK LK + + + E+
Sbjct 462 FPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEM 521
Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--------------PRH 993
++++ + H++II G C +G L +++E G+LR++L PR
Sbjct 522 EVMKLIGRHKNIINLLGVCTQEG--PLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRS 579
Query 994 SIG---LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
S G L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ V
Sbjct 580 SEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGV-H 638
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
+YY+ +G PV W APE L + + + SDVWSFG+ L+E+ T
Sbjct 639 HIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFT-------------- 684
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI---- 1166
L G + V L LL G R+ RP CP E+Y LM+ CW S RPTF+ L+
Sbjct 685 LGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALD 744
Query 1167 PILKTVHEKY 1176
+L V E+Y
Sbjct 745 KVLLAVSEEY 754
Score = 67.4 bits (163), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 72/289 (25%), Positives = 122/289 (42%), Gaps = 38/289 (13%)
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
DP P D+ + V + + S D+A E + H ++ + GVC +
Sbjct 490 DPARP--DQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLY 547
Query 685 MVTEYVEHGPLDVWLRRER-------------GHVPMAWKMVV--AQQLASALSYLENKN 729
++ E G L +LR R P+++ ++V A Q+A + YLE++
Sbjct 548 VIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRK 607
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPEC 783
+H ++ RN+L+ + +K++D G+ G ++ R+P W+APE
Sbjct 608 CIHRDLAARNVLVTEDNV-------MKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA 660
Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-C-PQL 841
L + D W FG L EI G +P E + HR+ P C P+L
Sbjct 661 L--FDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPEL 718
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTR----LQPHNLADVLTVNPDSPA 886
L +C P+QRP+F+ ++ L + + L LT P SP+
Sbjct 719 YGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPS 767
>sp|Q07407|FGFR1_DROME Fibroblast growth factor receptor homolog
1 OS=Drosophila melanogaster OX=7227 GN=htl PE=1 SV=3
Length=729
Score = 161 bits (408), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 98/289 (34%), Positives = 149/289 (52%), Gaps = 44/289 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961
LGEG FG+V + + +VAVK +K + +E+++++ + H +II
Sbjct 422 LGEGAFGRVVMA------EVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIIN 475
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------------------HSIGLAQL 1000
GCC G L +++EY P G+L+D+L + H I L
Sbjct 476 LLGCCSQNG--PLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDL 533
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+ FA QI GM YL ++ IHRDLAARNVL+ +D ++KI DFGLA+ + + +YYR +
Sbjct 534 IKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDI-QSTDYYRKNTN 592
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
G P+ W APE L+E + SDVWS+G+ L+E++T+ Q PT M+
Sbjct 593 GRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTY--GQQPYPTI-----------MS 639
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
L L G+R+ +P KC +Y LM+ CW A RP F ++ +
Sbjct 640 AEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYM 688
Score = 64.7 bits (156), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 67/282 (24%), Positives = 113/282 (40%), Gaps = 43/282 (15%)
Query 639 VVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K++ H DIA E + H ++ + G C + ++ EY HG L
Sbjct 440 VAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLK 499
Query 697 VWLRRER------------------GHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCG 737
+L + R HV ++ A Q+A + YL ++ +H ++
Sbjct 500 DFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAA 559
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGANSL 791
RN+L++ +K++D G+ S R+ R+P W+APE L
Sbjct 560 RNVLVS-------DDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQ--EKFY 610
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY----QRQHRLPEPSCPQLATLTSQ 847
+ D W +G L EI G+ P + +E+ + Y QR + P + L Q
Sbjct 611 DSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEK-PAKCSMNIYILMRQ 669
Query 848 CLTYEPTQRPSFRTILRDLTRL--QPHNLADVLTVNPDSPAS 887
C + RP F I+ + +L + DV N D+P S
Sbjct 670 CWHFNADDRPPFTEIVEYMDKLLQTKEDYLDVDIANLDTPPS 711
>sp|Q62662|FRK_RAT Tyrosine-protein kinase FRK OS=Rattus norvegicus
OX=10116 GN=Frk PE=1 SV=3
Length=506
Score = 157 bits (397), Expect = 2e-39, Method: Compositional matrix adjust.
Identities = 97/273 (36%), Positives = 143/273 (52%), Gaps = 27/273 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
++ ++ LG G FG+V ++ T VAVK LK G + + +E I+++L H
Sbjct 235 IQLLKRLGSGQFGEVWEGLWNNTTP-----VAVKTLKP--GSMDPNDFLREAQIMKSLRH 287
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAY 1013
+I+ C E + ++ E + GSL++YL I L Q + A Q+ GMAY
Sbjct 288 PKLIQLYAVC--TLEDPIYIITELMRHGSLQEYLQNDGGSKIRLTQQVDMAAQVASGMAY 345
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPEC 1072
L +Q+YIHRDLAARNVL+ + K+ DFGLA+ + + Y + + PV W APE
Sbjct 346 LESQNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEA 405
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
++ KF SDVWSFG+ LYE++T+ S MT ++ +L +
Sbjct 406 IRTNKFSIKSDVWSFGILLYEIITYGKMPYSG--------------MTGAQVIHMLGQNY 451
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
RLP+P CP + Y +M CW E RPTFE L
Sbjct 452 RLPQPSNCPEQFYSIMMECWNVEPKQRPTFETL 484
Score = 107 bits (268), Expect = 6e-23, Method: Compositional matrix adjust.
Identities = 91/330 (28%), Positives = 142/330 (43%), Gaps = 61/330 (18%)
Query 579 LSFHRVDQKEITQ-----LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
LS+ VDQ EI + L LG G V+EG ++ P
Sbjct 220 LSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGL-------------WNNTTP------- 259
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
V +K L P D F A +M + H L ++ VC ++TE + HG
Sbjct 260 -----VAVKTLKPGSMDPN-DFLREAQIMKSLRHPKLIQLYAVCTLEDPIYIITELMRHG 313
Query 694 PLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752
L +L+ + G + + ++ +A Q+AS ++YLE++N +H ++ RN+L+ G
Sbjct 314 SLQEYLQNDGGSKIRLTQQVDMAAQVASGMAYLESQNYIHRDLAARNVLV-------GEH 366
Query 753 PFIKLSDPGVG-LGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATL 804
K++D G+ + + E+ E + W APE + N S D W FG L
Sbjct 367 NIYKVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIR--TNKFSIKSDVWSFGILL 424
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862
EI G+ P + ++ H + +RLP+PS CP Q ++ +C EP QRP+F T+
Sbjct 425 YEIITYGKMPYSGMTGAQVIHMLGQNYRLPQPSNCPEQFYSIMMECWNVEPKQRPTFETL 484
Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVF 892
L PDS SD F
Sbjct 485 HWKLEDY----------FEPDSSYSDTNNF 504
>sp|Q24145|SHARK_DROME Tyrosine-protein kinase Shark OS=Drosophila
melanogaster OX=7227 GN=Shark PE=1 SV=2
Length=939
Score = 162 bits (411), Expect = 2e-39, Method: Compositional matrix adjust.
Identities = 102/293 (35%), Positives = 158/293 (54%), Gaps = 40/293 (14%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM----VAVKALKADCGPQHRSGWKQEIDILRTLYH 956
R++G G FG V + G GE VA+K L + ++ + +E ++ L H
Sbjct 666 REIGHGEFGSVH-SGWLLRKSGAGEESRLEVAIKMLSDEHS--NKQEFLREASVMMRLEH 722
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAY 1013
+ I++ G +GE L +V E PLGS+ Y+ H A+L ++A QI GM Y
Sbjct 723 KCIVRLIGIA--KGEM-LMMVQELAPLGSMLQYILDHGHEITANAELKVWASQIACGMHY 779
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
L +QH++HRDLAARN+LL KI DFG+++++ G Y+ + G P+ WYAPE
Sbjct 780 LESQHFVHRDLAARNILLTARHQAKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESF 839
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
F +ASDVWSFGVT++E+ S +PP G+++ + +L++ GER
Sbjct 840 NLGIFSHASDVWSFGVTIWEMF----SLGAPP----------YGEISNVDAIKLVDSGER 885
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTF-------------ENLIPILKTVH 1173
LP+P+ CP +Y +M++CW+ RPTF +NL +++TVH
Sbjct 886 LPQPNLCPAYIYAVMQSCWKERPKDRPTFVYLTEFFARDPDYQNLPELVQTVH 938
Score = 68.2 bits (165), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 70/241 (29%), Positives = 104/241 (43%), Gaps = 23/241 (10%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G L V +K+L H + F AS+M ++ H + + G+ +G +MV E
Sbjct 686 GAGEESRLEVAIKMLSDEHSN-KQEFLREASVMMRLEHKCIVRLIGIA-KGEMLMMVQEL 743
Query 690 VEHGPLDVWLRRERGH--VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
G + ++ + GH A V A Q+A + YLE+++ VH ++ RNILL
Sbjct 744 APLGSMLQYIL-DHGHEITANAELKVWASQIACGMHYLESQHFVHRDLAARNILLTARHQ 802
Query 748 AEGTSPFIKLSDPGV--GLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGF 800
A K+SD G+ L S E + + I W APE G S A D W F
Sbjct 803 A-------KISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESFNLGI--FSHASDVWSF 853
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPS 858
G T+ E+ G P S + RLP+P+ CP + + C P RP+
Sbjct 854 GVTIWEMFSLGAPPYGEISNVDAIKLVDSGERLPQPNLCPAYIYAVMQSCWKERPKDRPT 913
Query 859 F 859
F
Sbjct 914 F 914
>sp|Q498D6|FGFR4_RAT Fibroblast growth factor receptor 4 OS=Rattus
norvegicus OX=10116 GN=Fgfr4 PE=1 SV=1
Length=800
Score = 161 bits (408), Expect = 3e-39, Method: Compositional matrix adjust.
Identities = 107/301 (36%), Positives = 153/301 (51%), Gaps = 42/301 (14%)
Query 901 RDLGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956
+ LGEG FG+V D + VAVK LK + + + E+++++ + H
Sbjct 469 KPLGEGCFGQVVRAEALGMDSSRPDQTSTVAVKMLKDNASDKDLADLISEMEMMKLIGRH 528
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--------------PRHSIG---LAQ 999
++II G C +G L +++EY G+LR++L PR S G
Sbjct 529 KNIINLLGVCTQEG--PLYVIVEYAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPA 586
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ V +YY+
Sbjct 587 LVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDDVMKIADFGLARGV-HHIDYYKKTS 645
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
+G PV W APE L + + + SDVWSFG+ L+E+ T L G +
Sbjct 646 NGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFT--------------LGGSPYPGI 691
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI----PILKTVHEK 1175
V L LL G R+ RP CP E+Y LM+ CW S RPTF+ L+ +L V E+
Sbjct 692 PVEELFSLLREGHRMERPPNCPSELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEE 751
Query 1176 Y 1176
Y
Sbjct 752 Y 752
Score = 70.5 bits (171), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 66/260 (25%), Positives = 114/260 (44%), Gaps = 34/260 (13%)
Query 635 QELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
Q V +K+L + S D+A E + H ++ + GVC + ++ EY
Sbjct 494 QTSTVAVKMLKDNASDKDLADLISEMEMMKLIGRHKNIINLLGVCTQEGPLYVIVEYAAK 553
Query 693 GPLDVWLRRER-------------GHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCG 737
G L +LR R P+++ +V A Q+A + YLE++ +H ++
Sbjct 554 GNLREFLRARRPPGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDLAA 613
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSL 791
RN+L+ +K++D G+ G ++ R+P W+APE L +
Sbjct 614 RNVLVTE-------DDVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTH 666
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCL 849
+ D W FG L EI G +P E + HR+ P+CP +L L +C
Sbjct 667 QS--DVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRECW 724
Query 850 TYEPTQRPSFRTILRDLTRL 869
P+QRP+F+ ++ L ++
Sbjct 725 HAAPSQRPTFKQLVEALDKV 744
>sp|P00522|ABL_DROME Tyrosine-protein kinase Abl OS=Drosophila
melanogaster OX=7227 GN=Abl PE=1 SV=3
Length=1620
Score = 163 bits (413), Expect = 3e-39, Method: Compositional matrix adjust.
Identities = 101/290 (35%), Positives = 154/290 (53%), Gaps = 27/290 (9%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
TV P SP D + + LG G +G+V Y+ G VAVK LK D
Sbjct 353 TVFPLSPEPDEWEICRTDIMMKHKLGGGQYGEV----YEAVWKRYGNTVAVKTLKEDT-- 406
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSI 995
+ +E I++ + H ++++ G C E ++ E++ G+L D+L R ++
Sbjct 407 MALKDFLEEAAIMKEMKHPNLVQLIGVCTR--EPPFYIITEFMSHGNLLDFLRSAGRETL 464
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
LL A QI GM+YL +++YIHRDLAARN L+ +++LVK+ DFGLA+ + + + Y
Sbjct 465 DAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMRD--DTY 522
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
P+ W APE L KF SDVW+FGV L+E+ T+ S P ++L +
Sbjct 523 TAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMS----PYPAIDLTDVY 578
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L++G R+ RP CP EVY LM+ CW+ +A+ RPTF+++
Sbjct 579 HK----------LDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSI 618
Score = 104 bits (260), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 70/218 (32%), Positives = 112/218 (51%), Gaps = 21/218 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMV 713
F E A++M ++ H +L + GVC R P ++TE++ HG L +LR R + +
Sbjct 412 FLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLY 471
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
+A Q+AS +SYLE++N +H ++ RN L+ G + +K++D GL L R++
Sbjct 472 MATQIASGMSYLESRNYIHRDLAARNCLV-------GDNKLVKVAD--FGLARLMRDDTY 522
Query 774 ER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
I W APE L N ST D W FG L EI G +P + ++ H
Sbjct 523 TAHAGAKFPIKWTAPEGL--AYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHK 580
Query 827 YQRQHRLPE-PSC-PQLATLTSQCLTYEPTQRPSFRTI 862
+ +R+ P C P++ L QC ++ T RP+F++I
Sbjct 581 LDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSI 618
>sp|Q91287|FGFR3_PLEWA Fibroblast growth factor receptor 3 OS=Pleurodeles
waltl OX=8319 GN=FGFR3 PE=2 SV=1
Length=796
Score = 161 bits (407), Expect = 3e-39, Method: Compositional matrix adjust.
Identities = 106/295 (36%), Positives = 150/295 (51%), Gaps = 42/295 (14%)
Query 901 RDLGEGHFGKVSL-----YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL- 954
+ LGEG FG+V + D N T VAVK LK D + S E+++++ +
Sbjct 461 KPLGEGCFGQVVMADAVGIEKDKPNKATS--VAVKMLKDDATDKDLSDLVSEMEMMKMIG 518
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGL 997
H++II G C G L +++EY G+LR+YL P +
Sbjct 519 KHKNIINLLGACTQDG--PLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKLPEEQLTF 576
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
L+ A Q+ GM YL +Q IHRDLAARNVL+ +D ++KI DFGLA+ V +YY+
Sbjct 577 KDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDV-HNIDYYKK 635
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
+G PV W APE L + + + SDVWSFGV L+E+ T L G
Sbjct 636 TTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFT--------------LGGSPYP 681
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ V L +LL+ G R+ +P C E+Y +M+ CW S RPTF+ L+ L V
Sbjct 682 GIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFKQLVEDLDRV 736
Score = 63.5 bits (153), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 72/284 (25%), Positives = 126/284 (44%), Gaps = 44/284 (15%)
Query 639 VVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPL 695
V +K+L D + D++ E + H ++ + G C + GP ++V EY G L
Sbjct 490 VAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLV-EYASKGNL 548
Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740
+LR R +P + +K +V A Q+A + YL ++ +H ++ RN+
Sbjct 549 REYLRARRPPGMDYSFDTCKLPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNV 608
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGANSLSTA 794
L+ + +K++D G+ + ++ R+P W+APE L + +
Sbjct 609 LVTDDNV-------MKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQS- 660
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYE 852
D W FG L EI G +P E + HR+ +P+ C +L + +C
Sbjct 661 -DVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAV 719
Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896
P+QRP+F+ ++ DL R VLTV D +V ++Y
Sbjct 720 PSQRPTFKQLVEDLDR--------VLTVTSTDEYLDLSVPFEQY 755
>sp|Q04589|FGFR1_RAT Fibroblast growth factor receptor 1 OS=Rattus
norvegicus OX=10116 GN=Fgfr1 PE=1 SV=1
Length=822
Score = 161 bits (407), Expect = 4e-39, Method: Compositional matrix adjust.
Identities = 102/293 (35%), Positives = 149/293 (51%), Gaps = 38/293 (13%)
Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956
+ LGEG FG+V L D VAVK LK+D + S E+++++ + H
Sbjct 482 KPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKH 541
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999
++II G C G L +++EY G+LR+YL P +
Sbjct 542 KNIINLLGACTQDG--PLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKD 599
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+
Sbjct 600 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDI-HHIDYYKKTT 658
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
+G PV W APE L + + + SDVWSFGV L+E+ T L G +
Sbjct 659 NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--------------LGGSPNPGV 704
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L +
Sbjct 705 PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWNAVPSQRPTFKQLVEDLDRI 757
Score = 67.0 bits (162), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 63/257 (25%), Positives = 112/257 (44%), Gaps = 34/257 (13%)
Query 638 RVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+V +K+L D + D++ E + H ++ + G C + ++ EY G L
Sbjct 510 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL 569
Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740
+L+ R H P ++ K +V A Q+A + YL +K +H ++ RN+
Sbjct 570 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV 629
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTA 794
L+ + +K++D G+ ++ R+P W+APE L + +
Sbjct 630 LVTEDNV-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQS- 681
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATLTSQCLTYE 852
D W FG L EI G +P E + HR+ +PS +L + C
Sbjct 682 -DVWSFGVLLWEIFTLGGSPNPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWNAV 740
Query 853 PTQRPSFRTILRDLTRL 869
P+QRP+F+ ++ DL R+
Sbjct 741 PSQRPTFKQLVEDLDRI 757
>sp|P48025|KSYK_MOUSE Tyrosine-protein kinase SYK OS=Mus musculus
OX=10090 GN=Syk PE=1 SV=2
Length=629
Score = 159 bits (401), Expect = 4e-39, Method: Compositional matrix adjust.
Identities = 103/289 (36%), Positives = 144/289 (50%), Gaps = 27/289 (9%)
Query 883 DSPASDPT------VFHKRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+SP +DP V+ R L + D LG G+FG V Y V + +A
Sbjct 343 ESPYADPEEIRPKEVYLDRSLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEA 402
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994
+ P + E ++++ L + +I++ G CE + S LVME LG L YL ++
Sbjct 403 N-DPALKDELLAEANVMQQLDNPYIVRMIGICEAE---SWMLVMEMAELGPLNKYLQQNR 458
Query 995 -IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
I ++ Q+ GM YL +++HRDLAARNVLL KI DFGL+KA+
Sbjct 459 HIKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN 518
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
YY+ + G PV WYAPEC+ YKF SDVWSFGV ++E ++ Q P
Sbjct 519 YYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSY---GQKPYRG------ 569
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
M +T +LE+GER+ P CP E+Y LM CW + RP F
Sbjct 570 -----MKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGF 613
Score = 87.0 bits (214), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 64/228 (28%), Positives = 108/228 (47%), Gaps = 25/228 (11%)
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
DP+ D LA A++M Q+ + ++ + G+C ++V E E GPL+ +L++ R
Sbjct 404 DPALKDELLA---EANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNR- 458
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
H+ + + Q++ + YLE N VH ++ RN+LL T + K+SD G+
Sbjct 459 HIKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLV-------TQHYAKISDFGLS- 510
Query 765 GALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
AL +E + + W APEC+ S+ D W FG + E G+ P +
Sbjct 511 KALRADENYYKAQTHGKWPVKWYAPECI--NYYKFSSKSDVWSFGVLMWEAFSYGQKPYR 568
Query 817 SRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862
SE ++ R+ P+ CP ++ L + C TY+ RP F +
Sbjct 569 GMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFTAV 616
>sp|P21804|FGFR1_CHICK Fibroblast growth factor receptor 1 OS=Gallus
gallus OX=9031 GN=FGFR1 PE=2 SV=1
Length=819
Score = 160 bits (406), Expect = 5e-39, Method: Compositional matrix adjust.
Identities = 102/293 (35%), Positives = 149/293 (51%), Gaps = 38/293 (13%)
Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956
+ LGEG FG+V L D VAVK LK+D + S E+++++ + H
Sbjct 480 KPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKH 539
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999
++II G C G L +++EY G+LR+YL P +
Sbjct 540 KNIINLLGACTQDG--PLYVIVEYASKGNLREYLQARRPPGMEYCYNPTRIPEEQLSFKD 597
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+
Sbjct 598 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDI-HHIDYYKKTT 656
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
+G PV W APE L + + + SDVWSFGV L+E+ T L G +
Sbjct 657 NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGV 702
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L +
Sbjct 703 PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 755
Score = 67.0 bits (162), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 62/257 (24%), Positives = 113/257 (44%), Gaps = 34/257 (13%)
Query 638 RVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+V +K+L D + D++ E + H ++ + G C + ++ EY G L
Sbjct 508 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL 567
Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740
+L+ R +P +++K +V A Q+A + YL +K +H ++ RN+
Sbjct 568 REYLQARRPPGMEYCYNPTRIPEEQLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNV 627
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTA 794
L+ + +K++D G+ ++ R+P W+APE L + +
Sbjct 628 LVTEDNV-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQS- 679
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATLTSQCLTYE 852
D W FG L EI G +P E + HR+ +PS +L + C
Sbjct 680 -DVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAV 738
Query 853 PTQRPSFRTILRDLTRL 869
P+QRP+F+ ++ DL R+
Sbjct 739 PSQRPTFKQLVEDLDRI 755
>sp|P43405|KSYK_HUMAN Tyrosine-protein kinase SYK OS=Homo sapiens
OX=9606 GN=SYK PE=1 SV=1
Length=635
Score = 158 bits (400), Expect = 5e-39, Method: Compositional matrix adjust.
Identities = 102/289 (35%), Positives = 144/289 (50%), Gaps = 27/289 (9%)
Query 883 DSPASDPT------VFHKRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+SP +DP V+ R L + D LG G+FG V Y V + +A
Sbjct 349 ESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEA 408
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994
+ P + E ++++ L + +I++ G CE + S LVME LG L YL ++
Sbjct 409 N-DPALKDELLAEANVMQQLDNPYIVRMIGICEAE---SWMLVMEMAELGPLNKYLQQNR 464
Query 995 -IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ ++ Q+ GM YL +++HRDLAARNVLL KI DFGL+KA+
Sbjct 465 HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN 524
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
YY+ + G PV WYAPEC+ YKF SDVWSFGV ++E ++ Q P
Sbjct 525 YYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSY---GQKPYRG------ 575
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
M +T +LE+GER+ P CP E+Y LM CW + RP F
Sbjct 576 -----MKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGF 619
Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 65/228 (29%), Positives = 108/228 (47%), Gaps = 25/228 (11%)
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
DP+ D LA A++M Q+ + ++ + G+C ++V E E GPL+ +L++ R
Sbjct 410 DPALKDELLA---EANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNR- 464
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
HV + + Q++ + YLE N VH ++ RN+LL T + K+SD G+
Sbjct 465 HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLV-------TQHYAKISDFGLS- 516
Query 765 GALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
AL +E + + W APEC+ S+ D W FG + E G+ P +
Sbjct 517 KALRADENYYKAQTHGKWPVKWYAPECI--NYYKFSSKSDVWSFGVLMWEAFSYGQKPYR 574
Query 817 SRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862
SE ++ R+ P+ CP ++ L + C TY+ RP F +
Sbjct 575 GMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAV 622
>sp|P00534|ERBB_ALV Tyrosine-protein kinase transforming protein
erbB OS=Avian leukosis virus OX=11864 GN=V-ERBB PE=2 SV=2
Length=634
Score = 158 bits (400), Expect = 6e-39, Method: Compositional matrix adjust.
Identities = 104/307 (34%), Positives = 157/307 (51%), Gaps = 22/307 (7%)
Query 864 RDLTRL-QPHNLADVLTVNPDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
R L RL Q L + LT + ++P + + + KK++ LG G FG V + P +
Sbjct 97 RTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKVKVLGSGAFGTVYKGLWIPEGE 156
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VA+K L+ P+ E ++ ++ + H+ + G C ++QL+ + +
Sbjct 157 KVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS---TVQLITQLM 213
Query 982 PLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P G L DY+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI
Sbjct 214 PYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLVHRDLAARNVLVKTPQHVKI 273
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLAK + + Y E G P+ W A E + + + SDVWS+GVT++EL+T
Sbjct 274 TDFGLAKLLGADEKEYHA-EGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGS 332
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
GI + ++ +LE+GERLP+P C +VY +M CW +A R
Sbjct 333 KPYD---------GIPASE-----ISSVLEKGERLPQPPICTIDVYMIMVKCWMIDADSR 378
Query 1160 PTFENLI 1166
P F LI
Sbjct 379 PKFRELI 385
Score = 73.9 bits (180), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 52/221 (24%), Positives = 107/221 (48%), Gaps = 18/221 (8%)
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
+ A +M+ V + H+ + G+C+ ++T+ + +G L ++R + ++ + +
Sbjct 181 DEAYVMASVDNPHVCRLLGICLTSTVQ-LITQLMPYGCLLDYIREHKDNIGSQYLLNWCV 239
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE 774
Q+A ++YLE + LVH ++ RN+L+ T +K++D G+ LGA +E E
Sbjct 240 QIAKGMNYLEERRLVHRDLAARNVLVK-------TPQHVKITDFGLAKLLGADEKEYHAE 292
Query 775 --RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
++P W+A E + + + D W +G T+ E+ G P SE ++
Sbjct 293 GGKVPIKWMALESILHRIYTHQS--DVWSYGVTVWELMTFGSKPYDGIPASEISSVLEKG 350
Query 831 HRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869
RLP+P + + +C + RP FR ++ + +++
Sbjct 351 ERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIAEFSKM 391
>sp|Q95YD4|KIN32_CAEEL Inactive tyrosine-protein kinase kin-32
OS=Caenorhabditis elegans OX=6239 GN=kin-32 PE=1 SV=1
Length=867
Score = 160 bits (406), Expect = 6e-39, Method: Compositional matrix adjust.
Identities = 101/309 (33%), Positives = 157/309 (51%), Gaps = 26/309 (8%)
Query 879 TVNPDSPAS-DPTVFHKRYLKKIRDL-GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC 936
T+ P +P + D + +R L +++L G G FG V Y VAVK K D
Sbjct 347 TIRPKTPNNIDSNIRLRRELITLKELIGGGQFGNVYKAVYHDLEKDERIAVAVKVCKTDA 406
Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-- 994
P QE ++R H +II+ G C DQ + LV+E P G LR+YL +
Sbjct 407 EPADTQLILQESSLMRNFRHSNIIQLIGVCVDQ---PMWLVLELAPKGELREYLQQEKDW 463
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ L L LF QIC+ + YLH+ ++HRD+AARN+L+ + + VK+ DFGL++A+ Y
Sbjct 464 LPLRILTLFCSQICDSLVYLHSTRFVHRDIAARNILVCSPQCVKLADFGLSRALDYDAVY 523
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
R G P+ W APE + +F ASDVW FGV ++E+ + +G+
Sbjct 524 TASR--GKLPIKWLAPESVNYRQFSMASDVWMFGVCMWEIFS---------------LGV 566
Query 1115 A-QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN-CWETEASFRPTFENLIPILKTV 1172
+T + +E+G R P P+KCP +Y+ +++ W E RPT + + I++ V
Sbjct 567 KPWAGVTNSDVIMHIEQGSRPPCPEKCPTALYNFIRSKMWAIEPHKRPTVDQIYAIIEDV 626
Query 1173 HEKYQGQAP 1181
++ P
Sbjct 627 RQQIIQNIP 635
Score = 68.2 bits (165), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 69/242 (29%), Positives = 108/242 (45%), Gaps = 23/242 (10%)
Query 632 DRGQELRVVLKV--LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
++ + + V +KV D D L E +SLM H+++ + GVCV P +V E
Sbjct 390 EKDERIAVAVKVCKTDAEPADTQLILQE-SSLMRNFRHSNIIQLIGVCVDQPM-WLVLEL 447
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
G L +L++E+ +P+ + Q+ +L YL + VH ++ RNIL+
Sbjct 448 APKGELREYLQQEKDWLPLRILTLFCSQICDSLVYLHSTRFVHRDIAARNILVC------ 501
Query 750 GTSP-FIKLSDPGVGLG----ALSREERVER-IPWLAPECLPGGANSLSTAMDKWGFGAT 803
SP +KL+D G+ A+ R + I WLAPE + S A D W FG
Sbjct 502 --SPQCVKLADFGLSRALDYDAVYTASRGKLPIKWLAPESV--NYRQFSMASDVWMFGVC 557
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ--LATLTSQCLTYEPTQRPSFR 860
+ EI G P + S+ ++ R P P CP + S+ EP +RP+
Sbjct 558 MWEIFSLGVKPWAGVTNSDVIMHIEQGSRPPCPEKCPTALYNFIRSKMWAIEPHKRPTVD 617
Query 861 TI 862
I
Sbjct 618 QI 619
>sp|P00535|ERBB_AVIER Tyrosine-protein kinase transforming protein
erbB OS=Avian erythroblastosis virus (strain ES4) OX=79685
GN=V-ERBB PE=3 SV=1
Length=604
Score = 158 bits (399), Expect = 6e-39, Method: Compositional matrix adjust.
Identities = 105/307 (34%), Positives = 159/307 (52%), Gaps = 22/307 (7%)
Query 864 RDLTRL-QPHNLADVLTVNPDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
R L RL Q L + LT + ++P + + + KK++ LG G FG + + P +
Sbjct 97 RTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKVKVLGSGAFGTIYKGLWIPEGE 156
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VA+K L+ P+ E ++ ++ + H+ + G C ++QL+ + +
Sbjct 157 KVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLM 213
Query 982 PLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P G L DY+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI
Sbjct 214 PYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLVHRDLAARNVLVKTPQHVKI 273
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLAK + + Y E G P+ W A E + + + SDVWS+GVT++EL+T
Sbjct 274 TDFGLAKLLGADEKEYHA-EGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTF-- 330
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
S P GI + ++ +LE+GERLP+P C +VY +M CW +A R
Sbjct 331 --GSKPYD-----GIPASE-----ISSVLEKGERLPQPPICTIDVYMIMVKCWMIDADSR 378
Query 1160 PTFENLI 1166
P F LI
Sbjct 379 PKFRELI 385
Score = 73.9 bits (180), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 52/221 (24%), Positives = 107/221 (48%), Gaps = 18/221 (8%)
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
+ A +M+ V + H+ + G+C+ ++T+ + +G L ++R + ++ + +
Sbjct 181 DEAYVMASVDNPHVCRLLGICLTSTVQ-LITQLMPYGCLLDYIREHKDNIGSQYLLNWCV 239
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE 774
Q+A ++YLE + LVH ++ RN+L+ T +K++D G+ LGA +E E
Sbjct 240 QIAKGMNYLEERRLVHRDLAARNVLVK-------TPQHVKITDFGLAKLLGADEKEYHAE 292
Query 775 --RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
++P W+A E + + + D W +G T+ E+ G P SE ++
Sbjct 293 GGKVPIKWMALESILHRIYTHQS--DVWSYGVTVWELMTFGSKPYDGIPASEISSVLEKG 350
Query 831 HRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869
RLP+P + + +C + RP FR ++ + +++
Sbjct 351 ERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIAEFSKM 391
>sp|P50545|HCK_RAT Tyrosine-protein kinase HCK OS=Rattus norvegicus
OX=10116 GN=Hck PE=1 SV=4
Length=524
Score = 156 bits (395), Expect = 7e-39, Method: Compositional matrix adjust.
Identities = 94/286 (33%), Positives = 144/286 (50%), Gaps = 29/286 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ + LG G FG+V + Y+ VAVK +K G + E ++++TL H
Sbjct 260 LQMEKKLGAGQFGEVWMATYNKHTK-----VAVKTMKP--GSMSVEAFLAEANLMKTLQH 312
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAY 1013
+ ++K ++ + +V E++ GSL D+L L +L+ F+ QI EGMA+
Sbjct 313 DKLVKLHAVV---SQEPIFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQISEGMAF 369
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W APE +
Sbjct 370 IEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNE--YTAREGAKFPIKWTAPEAI 427
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
F SDVWSFG+ L E++T+ I M+ + LE G R
Sbjct 428 NFGSFTIKSDVWSFGILLMEIVTYGR--------------IPYPGMSNPEVIRALEHGYR 473
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+PRPD CP E+Y +M CW+ RPTFE + +L + + Q
Sbjct 474 MPRPDNCPEELYSIMIRCWKNRPEERPTFEYIQSVLDDFYTATESQ 519
Score = 85.9 bits (211), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 65/233 (28%), Positives = 110/233 (47%), Gaps = 19/233 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K + P + AF A+LM + H L +H V + P +VTE++ G L
Sbjct 284 KVAVKTMKPGSMSVE-AFLAEANLMKTLQHDKLVKLHAVVSQEP-IFIVTEFMAKGSLLD 341
Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G P+ + + Q++ ++++E +N +H ++ NIL++ S K
Sbjct 342 FLKSEEGSKQPLPKLIDFSAQISEGMAFIEQRNYIHRDLRAANILVS-------ASLVCK 394
Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ +RE I W APE + G S + D W FG L+EI G
Sbjct 395 IADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFG--SFTIKSDVWSFGILLMEIVTYG 452
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTI 862
P S E + +R+P P +CP +L ++ +C P +RP+F I
Sbjct 453 RIPYPGMSNPEVIRALEHGYRMPRPDNCPEELYSIMIRCWKNRPEERPTFEYI 505
>sp|P08103|HCK_MOUSE Tyrosine-protein kinase HCK OS=Mus musculus
OX=10090 GN=Hck PE=1 SV=4
Length=524
Score = 156 bits (394), Expect = 8e-39, Method: Compositional matrix adjust.
Identities = 93/286 (33%), Positives = 145/286 (51%), Gaps = 29/286 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ + LG G FG+V + Y+ VAVK +K G + E +++++L H
Sbjct 260 LQMEKKLGAGQFGEVWMATYNKHTK-----VAVKTMKP--GSMSVEAFLAEANLMKSLQH 312
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAY 1013
+ ++K ++ + +V E++ GSL D+L L +L+ F+ QI EGMA+
Sbjct 313 DKLVKLHAVV---SQEPIFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQISEGMAF 369
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W APE +
Sbjct 370 IEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNE--YTAREGAKFPIKWTAPEAI 427
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
F SDVWSFG+ L E++T+ I M+ + LE G R
Sbjct 428 NFGSFTIKSDVWSFGILLMEIVTYGR--------------IPYPGMSNPEVIRALEHGYR 473
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+PRPD CP E+Y++M CW+ RPTFE + +L + + Q
Sbjct 474 MPRPDNCPEELYNIMIRCWKNRPEERPTFEYIQSVLDDFYTATESQ 519
Score = 85.9 bits (211), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 65/233 (28%), Positives = 109/233 (47%), Gaps = 19/233 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K + P + AF A+LM + H L +H V + P +VTE++ G L
Sbjct 284 KVAVKTMKPGSMSVE-AFLAEANLMKSLQHDKLVKLHAVVSQEP-IFIVTEFMAKGSLLD 341
Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G P+ + + Q++ ++++E +N +H ++ NIL++ S K
Sbjct 342 FLKSEEGSKQPLPKLIDFSAQISEGMAFIEQRNYIHRDLRAANILVS-------ASLVCK 394
Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ +RE I W APE + G S + D W FG L+EI G
Sbjct 395 IADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFG--SFTIKSDVWSFGILLMEIVTYG 452
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTI 862
P S E + +R+P P +CP +L + +C P +RP+F I
Sbjct 453 RIPYPGMSNPEVIRALEHGYRMPRPDNCPEELYNIMIRCWKNRPEERPTFEYI 505
>sp|P11362|FGFR1_HUMAN Fibroblast growth factor receptor 1 OS=Homo
sapiens OX=9606 GN=FGFR1 PE=1 SV=3
Length=822
Score = 160 bits (404), Expect = 9e-39, Method: Compositional matrix adjust.
Identities = 102/293 (35%), Positives = 149/293 (51%), Gaps = 38/293 (13%)
Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956
+ LGEG FG+V L D VAVK LK+D + S E+++++ + H
Sbjct 482 KPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKH 541
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999
++II G C G L +++EY G+LR+YL P +
Sbjct 542 KNIINLLGACTQDG--PLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKD 599
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+
Sbjct 600 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDI-HHIDYYKKTT 658
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
+G PV W APE L + + + SDVWSFGV L+E+ T L G +
Sbjct 659 NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGV 704
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L +
Sbjct 705 PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 757
Score = 66.6 bits (161), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 63/257 (25%), Positives = 112/257 (44%), Gaps = 34/257 (13%)
Query 638 RVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+V +K+L D + D++ E + H ++ + G C + ++ EY G L
Sbjct 510 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL 569
Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740
+L+ R H P ++ K +V A Q+A + YL +K +H ++ RN+
Sbjct 570 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV 629
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTA 794
L+ + +K++D G+ ++ R+P W+APE L + +
Sbjct 630 LVTEDNV-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQS- 681
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATLTSQCLTYE 852
D W FG L EI G +P E + HR+ +PS +L + C
Sbjct 682 -DVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAV 740
Query 853 PTQRPSFRTILRDLTRL 869
P+QRP+F+ ++ DL R+
Sbjct 741 PSQRPTFKQLVEDLDRI 757
>sp|P22182|FGFR1_XENLA Fibroblast growth factor receptor 1 OS=Xenopus
laevis OX=8355 GN=fgfr1 PE=1 SV=1
Length=812
Score = 160 bits (404), Expect = 9e-39, Method: Compositional matrix adjust.
Identities = 101/293 (34%), Positives = 148/293 (51%), Gaps = 38/293 (13%)
Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956
+ LGEG FG+V + D VAVK LK+D + S E+++++ + H
Sbjct 476 KPLGEGCFGQVVMAEAIGLDKEKPNKVTKVAVKMLKSDASEKDLSDLISEMEMMKMIGKH 535
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999
++II G C G L +++EY G+LR+YL P +
Sbjct 536 KNIINLLGACTQDG--PLYVIVEYTSKGNLREYLRARRPPAMEYCYNPTCVPDQLLSFKD 593
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+
Sbjct 594 LVSCAYQVARGMDYLASKKCIHRDLAARNVLVTEDNIMKIADFGLARDI-HHIDYYKKTT 652
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
+G PV W APE L + + + SDVWSFGV L+E+ T L G +
Sbjct 653 NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGV 698
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ L +LL+ G R+ +P C E+Y +MK+CW S RPTF L+ L +
Sbjct 699 PMEELFKLLKEGHRMDKPTNCTNELYMMMKDCWHAMPSQRPTFNQLVEDLDRI 751
Score = 68.2 bits (165), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 64/257 (25%), Positives = 112/257 (44%), Gaps = 34/257 (13%)
Query 638 RVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+V +K+L D S D++ E + H ++ + G C + ++ EY G L
Sbjct 504 KVAVKMLKSDASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYTSKGNL 563
Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740
+LR R VP +++K +V A Q+A + YL +K +H ++ RN+
Sbjct 564 REYLRARRPPAMEYCYNPTCVPDQLLSFKDLVSCAYQVARGMDYLASKKCIHRDLAARNV 623
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTA 794
L+ + +K++D G+ ++ R+P W+APE L + +
Sbjct 624 LVTEDNI-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQS- 675
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATLTSQCLTYE 852
D W FG L EI G +P E + HR+ +P+ +L + C
Sbjct 676 -DVWSFGVLLWEIFTLGGSPYPGVPMEELFKLLKEGHRMDKPTNCTNELYMMMKDCWHAM 734
Query 853 PTQRPSFRTILRDLTRL 869
P+QRP+F ++ DL R+
Sbjct 735 PSQRPTFNQLVEDLDRI 751
>sp|Q91009|NTRK1_CHICK High affinity nerve growth factor receptor
(Fragment) OS=Gallus gallus OX=9031 GN=NTRK1 PE=1 SV=1
Length=778
Score = 159 bits (403), Expect = 9e-39, Method: Compositional matrix adjust.
Identities = 99/275 (36%), Positives = 143/275 (52%), Gaps = 35/275 (13%)
Query 902 DLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+LGEG FGKV L C + +VAVKALK + R +++E ++L L HEHI+
Sbjct 498 ELGEGAFGKVFLAECSHLLPEQEKTLVAVKALK-EVTENARLDFQREAELLTVLQHEHIV 556
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----------------SIGLAQLLLFA 1004
K+ G C + L +V EY+ G L +L H + L+ +L A
Sbjct 557 KFYGVCTEG--DPLIMVFEYMKHGDLNRFLRSHGPDAKILDQGQGQPCGQLTLSHMLQIA 614
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
QI GM YL + H++HRDLA RN L+ +D +VKIGDFG+++ + +YYRV P
Sbjct 615 TQIASGMVYLASLHFVHRDLATRNCLVGHDLVVKIGDFGMSRDI-YSTDYYRVGGRTMLP 673
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+ W PE + KF SD+WSFGV L+E+ T+ + P Q++
Sbjct 674 IRWMPPESILYRKFTTESDIWSFGVVLWEIFTY---GKQP-----------WYQLSNTEA 719
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
E + +G L RP CP EVY +M++CW+ E R
Sbjct 720 IECITQGRELERPRTCPSEVYDIMQSCWQREPQQR 754
Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 65/240 (27%), Positives = 103/240 (43%), Gaps = 31/240 (13%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K L + L F A L++ + H H+ +GVC G IMV EY++HG L+ +
Sbjct 524 VAVKALKEVTENARLDFQREAELLTVLQHEHIVKFYGVCTEGDPLIMVFEYMKHGDLNRF 583
Query 699 LRRER--------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
LR G + ++ + +A Q+AS + YL + + VH ++ RN L+
Sbjct 584 LRSHGPDAKILDQGQGQPCGQLTLSHMLQIATQIASGMVYLASLHFVHRDLATRNCLV-- 641
Query 745 LGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKW 798
G +K+ D G+ S + + I W+ PE + +T D W
Sbjct 642 -----GHDLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESIL--YRKFTTESDIW 694
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQR 856
FG L EI G+ P S +E + L P +CP ++ + C EP QR
Sbjct 695 SFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRTCPSEVYDIMQSCWQREPQQR 754
>sp|Q00944|FAK1_CHICK Focal adhesion kinase 1 OS=Gallus gallus
OX=9031 GN=PTK2 PE=1 SV=2
Length=1053
Score = 160 bits (406), Expect = 1e-38, Method: Compositional matrix adjust.
Identities = 102/275 (37%), Positives = 141/275 (51%), Gaps = 24/275 (9%)
Query 901 RDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
R +GEG FG V Y P N VA+K K R + QE +R H HI
Sbjct 426 RCIGEGQFGDVHQGIYMSPENPAMA--VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 483
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+K G E + ++ME LG LR +L + S+ LA L+L+A Q+ +AYL ++
Sbjct 484 VKLIGVI---TENPVWIIMELCTLGELRSFLQVRKFSLDLASLILYAYQLSTALAYLESK 540
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
++HRD+AARNVL+ VK+GDFGL++ + E YY+ + G P+ W APE + +
Sbjct 541 RFVHRDIAARNVLVSATDCVKLGDFGLSRYM-EDSTYYKASK-GKLPIKWMAPESINFRR 598
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F ASDVW FGV ++E+L H K ++IG +E GERLP P
Sbjct 599 FTSASDVWMFGVCMWEILMH-GVKPFQGVKNNDVIG-------------RIENGERLPMP 644
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
CP +Y LM CW + S RP F L L T+
Sbjct 645 PNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679
Score = 88.2 bits (217), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 64/224 (29%), Positives = 106/224 (47%), Gaps = 21/224 (9%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F + A M Q H H+ + GV P I + E G L +L+ + + +A ++
Sbjct 468 FLQEALTMRQFDHPHIVKLIGVITENPVWI-IMELCTLGELRSFLQVRKFSLDLASLILY 526
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
A QL++AL+YLE+K VH ++ RN+L++ + +KL D GL +
Sbjct 527 AYQLSTALAYLESKRFVHRDIAARNVLVS-------ATDCVKLGD--FGLSRYMEDSTYY 577
Query 775 R-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
+ I W+APE + ++A D W FG + EI G P Q ++
Sbjct 578 KASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 635
Query 828 QRQHRLP-EPSC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ RLP P+C P L +L ++C Y+P++RP F + L+ +
Sbjct 636 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679
>sp|P16092|FGFR1_MOUSE Fibroblast growth factor receptor 1 OS=Mus
musculus OX=10090 GN=Fgfr1 PE=1 SV=2
Length=822
Score = 159 bits (403), Expect = 1e-38, Method: Compositional matrix adjust.
Identities = 102/293 (35%), Positives = 149/293 (51%), Gaps = 38/293 (13%)
Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956
+ LGEG FG+V L D VAVK LK+D + S E+++++ + H
Sbjct 482 KPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKH 541
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999
++II G C G L +++EY G+LR+YL P +
Sbjct 542 KNIINLLGACTQDG--PLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKD 599
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+
Sbjct 600 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDI-HHIDYYKKTT 658
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
+G PV W APE L + + + SDVWSFGV L+E+ T L G +
Sbjct 659 NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGV 704
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L +
Sbjct 705 PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 757
Score = 66.6 bits (161), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 63/257 (25%), Positives = 112/257 (44%), Gaps = 34/257 (13%)
Query 638 RVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+V +K+L D + D++ E + H ++ + G C + ++ EY G L
Sbjct 510 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL 569
Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740
+L+ R H P ++ K +V A Q+A + YL +K +H ++ RN+
Sbjct 570 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV 629
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTA 794
L+ + +K++D G+ ++ R+P W+APE L + +
Sbjct 630 LVTEDNV-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQS- 681
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATLTSQCLTYE 852
D W FG L EI G +P E + HR+ +PS +L + C
Sbjct 682 -DVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAV 740
Query 853 PTQRPSFRTILRDLTRL 869
P+QRP+F+ ++ DL R+
Sbjct 741 PSQRPTFKQLVEDLDRI 757
>sp|Q90Z00|FGR1A_DANRE Fibroblast growth factor receptor 1-A OS=Danio
rerio OX=7955 GN=fgfr1a PE=1 SV=2
Length=810
Score = 159 bits (402), Expect = 1e-38, Method: Compositional matrix adjust.
Identities = 100/285 (35%), Positives = 148/285 (52%), Gaps = 38/285 (13%)
Query 903 LGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEH 958
LGEG FG+V + D VAVK LK+D + S E+++++ + H++
Sbjct 471 LGEGCFGQVMMAEAMGMDKEKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKN 530
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQLL 1001
II G C G L +++E+ G+LR+YL P ++ + L+
Sbjct 531 IINLLGACTQDG--PLYVIVEFAAKGNLREYLRVRRPPGMEYCYNPDQVPVENMSIKDLV 588
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+ +G
Sbjct 589 SCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDI-HHIDYYKKTTNG 647
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
PV W APE L + + + SDVWSFGV L+E+ T L G + V
Sbjct 648 RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGVPV 693
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L +LL+ G R+ RP C E+Y +M++CW S RPTF+ L+
Sbjct 694 EELFKLLKEGHRMDRPSTCTHELYMMMRDCWHAVPSQRPTFKQLV 738
Score = 67.4 bits (163), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 68/271 (25%), Positives = 115/271 (42%), Gaps = 37/271 (14%)
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680
MD E P +R ++ V + D + D++ E + H ++ + G C +
Sbjct 487 MDKEKP-----NRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQD 541
Query 681 PENIMVTEYVEHGPLDVWLRRER----------GHVP---MAWKMVV--AQQLASALSYL 725
++ E+ G L +LR R VP M+ K +V A Q+A + YL
Sbjct 542 GPLYVIVEFAAKGNLREYLRVRRPPGMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYL 601
Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WL 779
+K +H ++ RN+L+ + +K++D G+ ++ R+P W+
Sbjct 602 ASKKCIHRDLAARNVLVTEDNV-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWM 654
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-C 838
APE L + + D W FG L EI G +P E + HR+ PS C
Sbjct 655 APEALFDRIYTHQS--DVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDRPSTC 712
Query 839 P-QLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+L + C P+QRP+F+ ++ DL R
Sbjct 713 THELYMMMRDCWHAVPSQRPTFKQLVEDLDR 743
>sp|Q95M30|HCK_MACFA Tyrosine-protein kinase HCK OS=Macaca fascicularis
OX=9541 GN=HCK PE=2 SV=3
Length=504
Score = 154 bits (390), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 93/286 (33%), Positives = 144/286 (50%), Gaps = 29/286 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
LK + LG G FG+V + Y+ VAVK +K G + E ++++TL H
Sbjct 240 LKLEKKLGAGQFGEVWMATYNKHTK-----VAVKTMKP--GSMSVEAFLAEANLMKTLQH 292
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAY 1013
+ ++K + + ++ E++ GSL D+L L +L+ F+ QI EGMA+
Sbjct 293 DKLVKLHAVVTKE---PIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAF 349
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W APE +
Sbjct 350 IEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNE--YTAREGAKFPIKWTAPEAI 407
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
SDVWSFG+ L E++T+ I M+ + LERG R
Sbjct 408 NFGSSTIKSDVWSFGILLMEIVTYGR--------------IPYPGMSNPEVIRALERGYR 453
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+PRP+ CP E+Y++M CW+ RPTFE + +L + + Q
Sbjct 454 MPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ 499
Score = 90.5 bits (223), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 65/233 (28%), Positives = 113/233 (48%), Gaps = 19/233 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K + P + AF A+LM + H L +H V + P I +TE++ G L
Sbjct 264 KVAVKTMKPGSMSVE-AFLAEANLMKTLQHDKLVKLHAVVTKEPIYI-ITEFMAKGSLLD 321
Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ + G P+ + + Q+A ++++E +N +H ++ NIL++ S K
Sbjct 322 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-------ASLVCK 374
Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ +RE I W APE + G++++ + D W FG L+EI G
Sbjct 375 IADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSSTIKS--DVWSFGILLMEIVTYG 432
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTI 862
P S E +R +R+P P +CP +L + +C P +RP+F I
Sbjct 433 RIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYI 485
>sp|P18460|FGFR3_CHICK Fibroblast growth factor receptor 3 OS=Gallus
gallus OX=9031 GN=FGFR3 PE=2 SV=1
Length=806
Score = 158 bits (400), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 115/351 (33%), Positives = 167/351 (48%), Gaps = 39/351 (11%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT-VFHKRYLKKIRD 902
L Q ++ E + T L +TRL + + V+ DP + L +
Sbjct 412 LKRQQVSLESNSSMNSNTPLVRITRLSSSDGPMLANVSELELPPDPKWELARSRLTLGKP 471
Query 903 LGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEH 958
LGEG FG+V + D VAVK LK D + S E+++++ + H++
Sbjct 472 LGEGCFGQVVMAEAIGIDKDKPNKAITVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 531
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQLL 1001
II G C G L +++EY G+LR+YL P + L+
Sbjct 532 IINLLGACTQDG--PLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKLPEEQLTFKDLV 589
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
A Q+ GM YL +Q IHRDLAARNVL+ D ++KI DFGLA+ V +YY+ +G
Sbjct 590 SCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDV-HNIDYYKKTTNG 648
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
PV W APE L + + + SDVWSFGV L+E+ T L G + V
Sbjct 649 RLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGIPV 694
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
L +LL+ G R+ +P C ++Y +M+ CW S RPTF+ L+ L V
Sbjct 695 EELFKLLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRV 745
Score = 64.3 bits (155), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 65/262 (25%), Positives = 117/262 (45%), Gaps = 36/262 (14%)
Query 634 GQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYV 690
+ + V +K+L D + D++ E + H ++ + G C + GP ++V EY
Sbjct 494 NKAITVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLV-EYA 552
Query 691 EHGPLDVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNV 735
G L +LR R +P + +K +V A Q+A + YL ++ +H ++
Sbjct 553 SKGNLREYLRARRPPGMDYSFDTCKLPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDL 612
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGAN 789
RN+L+ +K++D G+ + ++ R+P W+APE L
Sbjct 613 AARNVLVTE-------DNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVY 665
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQ 847
+ + D W FG L EI G +P E + HR+ +P+ C L + +
Sbjct 666 THQS--DVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRE 723
Query 848 CLTYEPTQRPSFRTILRDLTRL 869
C P+QRP+F+ ++ DL R+
Sbjct 724 CWHAVPSQRPTFKQLVEDLDRV 745
>sp|Q91738|FAK1_XENLA Focal adhesion kinase 1 OS=Xenopus laevis
OX=8355 GN=ptk2 PE=2 SV=2
Length=1068
Score = 159 bits (403), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 101/276 (37%), Positives = 144/276 (52%), Gaps = 26/276 (9%)
Query 901 RDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
R +GEG FG V Y P N VA+K K R + QE +R H HI
Sbjct 439 RCIGEGQFGDVHQGVYMSPENPAMA--VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 496
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+K G E + ++ME LG LR +L ++S+ LA L+L++ Q+ +AYL ++
Sbjct 497 VKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYSYQLSTALAYLESK 553
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
++HRD+AARNVL+ + VK+GDFGL++ + E YY+ + G P+ W APE + +
Sbjct 554 RFVHRDIAARNVLVSSSDCVKLGDFGLSRYM-EDSTYYKASK-GKLPIKWMAPESINFRR 611
Query 1078 FYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
F ASDVW FGV ++E+L + Q K ++IG +E GERLP
Sbjct 612 FTSASDVWMFGVCMWEILMYGVKPFQG--VKNNDVIG-------------RIENGERLPM 656
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P CP +Y LM CW + S RP F L L T+
Sbjct 657 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 692
Score = 87.8 bits (216), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 64/224 (29%), Positives = 107/224 (48%), Gaps = 21/224 (9%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F + A M Q H H+ + GV P I + E G L +L+ + + +A ++
Sbjct 481 FLQEALTMRQFDHPHIVKLIGVITENPVWI-IMELCTLGELRSFLQVRKYSLDLASLILY 539
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ QL++AL+YLE+K VH ++ RN+L++ +S +KL D GL +
Sbjct 540 SYQLSTALAYLESKRFVHRDIAARNVLVS-------SSDCVKLGD--FGLSRYMEDSTYY 590
Query 775 R-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
+ I W+APE + ++A D W FG + EI G P Q ++
Sbjct 591 KASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWEILMYGVKPFQGVKNNDVIGRI 648
Query 828 QRQHRLP-EPSC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ RLP P+C P L +L ++C Y+P++RP F + L+ +
Sbjct 649 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 692
>sp|P42688|SRK2_SPOLA Tyrosine-protein kinase SRK2 (Fragment)
OS=Spongilla lacustris OX=6055 GN=SRK2 PE=2 SV=1
Length=362
Score = 150 bits (380), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 110/328 (34%), Positives = 161/328 (49%), Gaps = 43/328 (13%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVN---PDSPASDPTV-----------FHKRYLKK 899
T+R F T L+DL + N +D L VN P P P + + +
Sbjct 40 TRRAVFNT-LKDLVQYY-QNESDGLCVNLRQPCRPLERPQIDLSHKTKDMWEISRDSITL 97
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
IR LG G FG+V ++ + VAVK LKA G + + E I++ L H +
Sbjct 98 IRKLGAGQFGEVYQGLWNNSTP-----VAVKTLKA--GTMQPAAFLAEAQIMKKLRHPKL 150
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQ 1017
I+ C QGE + ++ E + GSL DYL + + L QL+ A Q+ GMAYL
Sbjct 151 IQLYAVCT-QGE-PVYIITELMSKGSLLDYLQGEAGALKLPQLIDMAAQVAAGMAYLELH 208
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+YIHRDLAARN+L+ ++ + K+ DFGLA+ + Y E P+ W APE +
Sbjct 209 NYIHRDLAARNILVGDNNICKVADFGLARLIVSDD--YNATEGAKFPIKWTAPEAALFNR 266
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFG+ + EL+T+ I M+ + + L++G R+P P
Sbjct 267 FSIKSDVWSFGILITELVTYGR--------------IPYPGMSNAEVLQNLDKGYRMPCP 312
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165
P +Y +M +CW+ + RPTFE L
Sbjct 313 VTTPESLYQIMLDCWKRNPADRPTFEAL 340
Score = 88.6 bits (218), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 104/421 (25%), Positives = 173/421 (41%), Gaps = 73/421 (17%)
Query 471 YLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELG 530
+L+ S S P L++ Q D ++ R+RK +G F + F ++++L
Sbjct 2 FLVRESESKPGDYSLSI----QDGDNVKHYRIRKL----DEGGFFITRRA-VFNTLKDLV 52
Query 531 AALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEIT 590
Q + C +LR+ C P +L S +T ++ ++S + IT
Sbjct 53 QYYQN---ESDGLCVNLRQPCRPLERPQIDL--------SHKTKDMWEIS-----RDSIT 96
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ LG G VY+G + + P V +K L
Sbjct 97 LIRKLGAGQFGEVYQG---LWNNSTP----------------------VAVKTLKAGTMQ 131
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
A AF A +M ++ H L ++ VC +G ++TE + G L +L+ E G + +
Sbjct 132 PA-AFLAEAQIMKKLRHPKLIQLYAVCTQGEPVYIITELMSKGSLLDYLQGEAGALKLPQ 190
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ +A Q+A+ ++YLE N +H ++ RNIL+ G + K++D G+ +S +
Sbjct 191 LIDMAAQVAAGMAYLELHNYIHRDLAARNILV-------GDNNICKVADFGLARLIVSDD 243
Query 771 ERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
I W APE N S D W FG + E+ G P S +E
Sbjct 244 YNATEGAKFPIKWTAPEA--ALFNRFSIKSDVWSFGILITELVTYGRIPYPGMSNAEVLQ 301
Query 826 FYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI---LRDLTRL---QPHNLADV 877
+ +R+P P + P+ L + C P RP+F + L D L Q + ADV
Sbjct 302 NLDKGYRMPCPVTTPESLYQIMLDCWKRNPADRPTFEALQWRLEDFFVLDAGQYQHAADV 361
Query 878 L 878
L
Sbjct 362 L 362
>sp|Q09147|FGFR2_DROME Fibroblast growth factor receptor homolog
2 OS=Drosophila melanogaster OX=7227 GN=btl PE=2 SV=3
Length=1052
Score = 159 bits (402), Expect = 3e-38, Method: Compositional matrix adjust.
Identities = 100/292 (34%), Positives = 155/292 (53%), Gaps = 44/292 (15%)
Query 903 LGEGHFGKVSLYCYD--PTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTL-YHEH 958
LGEG FG+V + + P + E +VAVK +K + + +E+++++ + H +
Sbjct 718 LGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHIN 777
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------------------------ 994
II GCC G L +++EY P G+L+D+L ++
Sbjct 778 IINLLGCCSQGG--PLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQH 835
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+G +L FA QI GM YL ++ IHRDLAARNVL+ + ++KI DFGLA+ + + EY
Sbjct 836 LGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDI-QDTEY 894
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
YR +G P+ W APE L+E K+ SDVWS+GV L+E++T+ D P +
Sbjct 895 YRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQ----PYPHI----- 945
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
++ L L G+R+ +P KC +Y +M+ CW E+ RPTF L+
Sbjct 946 ----LSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELV 993
Score = 57.0 bits (136), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 59/262 (23%), Positives = 106/262 (40%), Gaps = 44/262 (17%)
Query 636 ELRVVLKVLDPSHHDIALA-FYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHG 693
E V +K++ H D +A +M + H ++ + G C +G ++ EY HG
Sbjct 742 ETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHG 801
Query 694 PLDVWLRRERGHVP--------------------MAWKMVV--AQQLASALSYLENKNLV 731
L +L++ R P + K + A Q+A + YL ++ +
Sbjct 802 NLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCI 861
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLP 785
H ++ RN+L++ +K++D G+ R+ R+P W+APE L
Sbjct 862 HRDLAARNVLVS-------DGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQ 914
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY----QRQHRLPEPSCPQL 841
+ D W +G L EI G+ P +E+ + Y QR + P +
Sbjct 915 --EKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEK-PAKCSLNI 971
Query 842 ATLTSQCLTYEPTQRPSFRTIL 863
+ QC +E RP+F ++
Sbjct 972 YVVMRQCWHFESCARPTFAELV 993
>sp|O42127|FGFR3_XENLA Fibroblast growth factor receptor 3 OS=Xenopus
laevis OX=8355 GN=fgfr3 PE=2 SV=1
Length=802
Score = 158 bits (399), Expect = 3e-38, Method: Compositional matrix adjust.
Identities = 102/293 (35%), Positives = 147/293 (50%), Gaps = 38/293 (13%)
Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956
+ LGEG FG+V + D VAVK LK D + S E+++++ + H
Sbjct 466 KPLGEGCFGQVVMAEAIGIDKERPNKPATVAVKMLKDDATDKDLSDLVSEMEMMKMIGKH 525
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999
++II G C G L +++EY GSLR+YL P +
Sbjct 526 KNIINLLGACTQDG--PLYVLVEYASKGSLREYLKARRPPGMDYSFDACKIPAEQLTFKD 583
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
L+ A Q+ GM YL +Q IHRDLAARNVL+ +D ++KI DFGLA+ + +YY+
Sbjct 584 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDI-HNIDYYKKTT 642
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
+G PV W APE L + + + SDVWS+GV L+E+ T L G +
Sbjct 643 NGRLPVKWMAPEALFDRIYTHHSDVWSYGVLLWEIFT--------------LGGSPYPGI 688
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
V L +LL+ G R+ +P C E+Y +M+ CW S RP F+ L+ L V
Sbjct 689 PVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPAFKQLVEDLDRV 741
Score = 61.6 bits (148), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 70/284 (25%), Positives = 127/284 (45%), Gaps = 44/284 (15%)
Query 639 VVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPL 695
V +K+L D + D++ E + H ++ + G C + GP ++V EY G L
Sbjct 495 VAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLV-EYASKGSL 553
Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740
+L+ R +P + +K +V A Q+A + YL ++ +H ++ RN+
Sbjct 554 REYLKARRPPGMDYSFDACKIPAEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNV 613
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGANSLSTA 794
L+ + +K++D G+ + ++ R+P W+APE L + +
Sbjct 614 LVTDDNV-------MKIADFGLARDIHNIDYYKKTTNGRLPVKWMAPEALFDRIYTHHS- 665
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYE 852
D W +G L EI G +P E + HR+ +P+ C +L + +C
Sbjct 666 -DVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAV 724
Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896
P+QRP+F+ ++ DL R VLTV + D +V ++Y
Sbjct 725 PSQRPAFKQLVEDLDR--------VLTVTSTNEYLDLSVAFEQY 760
>sp|P13388|XMRK_XIPMA Melanoma receptor tyrosine-protein kinase
OS=Xiphophorus maculatus OX=8083 GN=xmrk PE=2 SV=2
Length=1167
Score = 159 bits (402), Expect = 3e-38, Method: Compositional matrix adjust.
Identities = 105/301 (35%), Positives = 154/301 (51%), Gaps = 21/301 (7%)
Query 869 LQPHNLADVLTVNPDSPASD-PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
LQ L + LT + +P + + KK R LG G FG V ++P + V
Sbjct 681 LQEKELVEPLTPSGQAPNQAFLRILKETEFKKDRVLGSGAFGTVYKGLWNPDGENIRIPV 740
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K L+ P+ E ++ ++ H H+ + G C ++QLV + +P G L
Sbjct 741 AIKVLREATSPKVNQEVLDEAYVMASVDHPHVCRLLGICL---TSAVQLVTQLMPYGCLL 797
Query 988 DYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
DY+ +H I LL + QI +GM YL +H +HRDLAARNVLL N VKI DFGL+
Sbjct 798 DYVRQHQERICGQWLLNWCVQIAKGMNYLEERHLVHRDLAARNVLLKNPNHVKITDFGLS 857
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
K + + Y+ + G P+ W A E + ++ + + SDVWS+GVT++EL+T S P
Sbjct 858 KLLTADEKEYQA-DGGKVPIKWMALESILQWTYTHQSDVWSYGVTVWELMTF----GSKP 912
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ IA +LE GERLP+P C EVY ++ CW + S RP F L
Sbjct 913 YDGIPAKEIA----------SVLENGERLPQPPICTIEVYMIILKCWMIDPSSRPRFREL 962
Query 1166 I 1166
+
Sbjct 963 V 963
Score = 75.9 bits (185), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 59/247 (24%), Positives = 118/247 (48%), Gaps = 21/247 (9%)
Query 634 GQELR--VVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
G+ +R V +KVL + + + + A +M+ V H H+ + G+C+ +VT+ +
Sbjct 733 GENIRIPVAIKVLREATSPKVNQEVLDEAYVMASVDHPHVCRLLGICLTSAVQ-LVTQLM 791
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
+G L ++R+ + + W + Q+A ++YLE ++LVH ++ RN+LL
Sbjct 792 PYGCLLDYVRQHQERICGQWLLNWCVQIAKGMNYLEERHLVHRDLAARNVLLK------- 844
Query 751 TSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGATL 804
+K++D G+ L A +E + + I W+A E + + + D W +G T+
Sbjct 845 NPNHVKITDFGLSKLLTADEKEYQADGGKVPIKWMALESILQW--TYTHQSDVWSYGVTV 902
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTI 862
E+ G P E + RLP+P ++ + +C +P+ RP FR +
Sbjct 903 WELMTFGSKPYDGIPAKEIASVLENGERLPQPPICTIEVYMIILKCWMIDPSSRPRFREL 962
Query 863 LRDLTRL 869
+ + +++
Sbjct 963 VGEFSQM 969
>sp|P22607|FGFR3_HUMAN Fibroblast growth factor receptor 3 OS=Homo
sapiens OX=9606 GN=FGFR3 PE=1 SV=1
Length=806
Score = 158 bits (399), Expect = 3e-38, Method: Compositional matrix adjust.
Identities = 102/293 (35%), Positives = 147/293 (50%), Gaps = 38/293 (13%)
Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956
+ LGEG FG+V + D VAVK LK D + S E+++++ + H
Sbjct 476 KPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKH 535
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999
++II G C G L +++EY G+LR++L P +
Sbjct 536 KNIINLLGACTQGG--PLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKD 593
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
L+ A Q+ GM YL +Q IHRDLAARNVL+ D ++KI DFGLA+ V +YY+
Sbjct 594 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDV-HNLDYYKKTT 652
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
+G PV W APE L + + + SDVWSFGV L+E+ T L G +
Sbjct 653 NGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGI 698
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
V L +LL+ G R+ +P C ++Y +M+ CW S RPTF+ L+ L V
Sbjct 699 PVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRV 751
Score = 65.9 bits (159), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 64/265 (24%), Positives = 117/265 (44%), Gaps = 35/265 (13%)
Query 631 RDRGQE-LRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
+DR + + V +K+L D + D++ E + H ++ + G C +G ++
Sbjct 496 KDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLV 555
Query 688 EYVEHGPLDVWLRRERG-------------HVPMAWKMVV--AQQLASALSYLENKNLVH 732
EY G L +LR R + +K +V A Q+A + YL ++ +H
Sbjct 556 EYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIH 615
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPG 786
++ RN+L+ + +K++D G+ + ++ R+P W+APE L
Sbjct 616 RDLAARNVLVTEDNV-------MKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFD 668
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATL 844
+ + D W FG L EI G +P E + HR+ +P+ C L +
Sbjct 669 RVYTHQS--DVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMI 726
Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869
+C P+QRP+F+ ++ DL R+
Sbjct 727 MRECWHAAPSQRPTFKQLVEDLDRV 751
>sp|P18461|FGFR2_CHICK Fibroblast growth factor receptor 2 OS=Gallus
gallus OX=9031 GN=FGFR2 PE=2 SV=1
Length=823
Score = 158 bits (399), Expect = 4e-38, Method: Compositional matrix adjust.
Identities = 104/311 (33%), Positives = 155/311 (50%), Gaps = 43/311 (14%)
Query 892 FHKRYLKKIRDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
F + L + LGEG FG+V + D VAVK LK D + S E+
Sbjct 478 FPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKEAVTVAVKMLKDDATEKDLSDLVSEM 537
Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------------- 990
++++ + H++II G C G L +++EY G+LR+YL
Sbjct 538 EMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPPGMEYSFDINRV 595
Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
P + L+ Q+ GM YL +Q IHRDLAARNVL+ + ++KI DFGLA+ +
Sbjct 596 PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDI-N 654
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
+YY+ +G PV W APE L + + + SDVWSFGV ++E+ T
Sbjct 655 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT-------------- 700
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
L G + V L +LL+ G R+ +P C E+Y +M++CW+ S RPTF+ L+ L
Sbjct 701 LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWQAVPSQRPTFKQLVEDLD 760
Query 1171 -----TVHEKY 1176
T +E+Y
Sbjct 761 RILTLTTNEEY 771
Score = 71.2 bits (173), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 65/265 (25%), Positives = 119/265 (45%), Gaps = 35/265 (13%)
Query 631 RDRGQE-LRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
+DR +E + V +K+L D + D++ E + H ++ + G C + ++
Sbjct 507 KDRPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIV 566
Query 688 EYVEHGPLDVWLRRER----------GHVP---MAWKMVVA--QQLASALSYLENKNLVH 732
EY G L +LR R VP M +K +V+ QLA + YL ++ +H
Sbjct 567 EYASKGNLREYLRARRPPGMEYSFDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIH 626
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE--RIP--WLAPECLPG 786
++ RN+L+ + +K++D G+ + + ++ R+P W+APE L
Sbjct 627 RDLAARNVLVTENNV-------MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFD 679
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATL 844
+ + D W FG + EI G +P E + HR+ +P+ +L +
Sbjct 680 RVYTHQS--DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMM 737
Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869
C P+QRP+F+ ++ DL R+
Sbjct 738 MRDCWQAVPSQRPTFKQLVEDLDRI 762
>sp|Q9V9J3|SRC42_DROME Tyrosine-protein kinase Src42A OS=Drosophila
melanogaster OX=7227 GN=Src42A PE=1 SV=1
Length=517
Score = 154 bits (389), Expect = 4e-38, Method: Compositional matrix adjust.
Identities = 100/274 (36%), Positives = 137/274 (50%), Gaps = 30/274 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
LK +R LG G FG V ++ T VA+K LK+ G + E I++ L H
Sbjct 248 LKFVRKLGSGQFGDVWEGLWNNTTP-----VAIKTLKS--GTMDPKDFLAEAQIMKKLRH 300
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQICEGM 1011
+I+ C E+ + ++ E + GSL +YL S+ + L+ A QI GM
Sbjct 301 TKLIQLYAVC--TVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGM 358
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
AYL +Q+YIHRDLAARNVL+ + +VKI DFGLA+ + E Y R P+ W APE
Sbjct 359 AYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDE--YEARVGARFPIKWTAPE 416
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
KF SDVWSFG+ L EL+T+ I MT + +E G
Sbjct 417 AANYSKFSIKSDVWSFGILLTELVTYGR--------------IPYPGMTNAEVLTQVEHG 462
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
R+P+P C +Y +M CW + RPTFE L
Sbjct 463 YRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETL 496
Score = 91.7 bits (226), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 64/234 (27%), Positives = 112/234 (48%), Gaps = 23/234 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH---VPMAWK 711
F A +M ++ HT L ++ VC ++TE ++HG L +L+ G + M
Sbjct 288 FLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTL 347
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771
+ +A Q+A+ ++YLE++N +H ++ RN+L+ G +K++D GL L +E+
Sbjct 348 IDMAAQIAAGMAYLESQNYIHRDLAARNVLV-------GDGNIVKIAD--FGLARLIKED 398
Query 772 RVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
E I W APE + S D W FG L E+ G P + +E
Sbjct 399 EYEARVGARFPIKWTAPEA--ANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVL 456
Query 825 HFYQRQHRLPE-PSC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
+ +R+P+ P+C P+L + +C +P +RP+F T+ L + +D
Sbjct 457 TQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDFYTSDQSD 510
>sp|Q90413|FGFR4_DANRE Fibroblast growth factor receptor 4 OS=Danio
rerio OX=7955 GN=fgfr4 PE=1 SV=1
Length=922
Score = 158 bits (400), Expect = 4e-38, Method: Compositional matrix adjust.
Identities = 104/310 (34%), Positives = 156/310 (50%), Gaps = 42/310 (14%)
Query 892 FHKRYLKKIRDLGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
F + L + LGEG FG+V Y + N VAVK LK D + + E+
Sbjct 573 FPRENLTLGKPLGEGCFGQVVRAEAYGINKENQDHMATVAVKMLKDDATDKDLADLISEM 632
Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------------- 990
++++ + H++II G C G L +++EY GSLR+YL
Sbjct 633 ELMKVMDKHKNIINLLGVCTQDG--PLYVLVEYASKGSLREYLRARRPPGMDYTFDVTKV 690
Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
P + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ V +
Sbjct 691 PEEQLTFKDLVSCAYQVARGMEYLASKRCIHRDLAARNVLVTEDNVMKIADFGLARGVHQ 750
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
+YY+ +G PV W APE L + + + SDVWSFGV ++E+ T
Sbjct 751 -IDYYKKTTNGRMPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT-------------- 795
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP--- 1167
L G + V L +LL+ G R+ +P C E+Y M+ CW + RPTF+ L+
Sbjct 796 LGGSPYPGIPVEELFKLLKEGHRMDKPSNCTHELYMKMRECWHAVPTQRPTFKQLVEELD 855
Query 1168 -ILKTVHEKY 1176
+L ++ ++Y
Sbjct 856 RVLVSISDEY 865
Score = 71.6 bits (174), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 70/257 (27%), Positives = 116/257 (45%), Gaps = 36/257 (14%)
Query 639 VVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPL 695
V +K+L D + D+A E + H ++ + GVC + GP ++V EY G L
Sbjct 611 VAVKMLKDDATDKDLADLISEMELMKVMDKHKNIINLLGVCTQDGPLYVLV-EYASKGSL 669
Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740
+LR R VP + +K +V A Q+A + YL +K +H ++ RN+
Sbjct 670 REYLRARRPPGMDYTFDVTKVPEEQLTFKDLVSCAYQVARGMEYLASKRCIHRDLAARNV 729
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTA 794
L+ +K++D G+ G ++ R+P W+APE L + +
Sbjct 730 LVTE-------DNVMKIADFGLARGVHQIDYYKKTTNGRMPVKWMAPEALFDRVYTHQS- 781
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYE 852
D W FG + EI G +P E + HR+ +PS C +L +C
Sbjct 782 -DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPSNCTHELYMKMRECWHAV 840
Query 853 PTQRPSFRTILRDLTRL 869
PTQRP+F+ ++ +L R+
Sbjct 841 PTQRPTFKQLVEELDRV 857
>sp|Q91147|FGFR2_NOTVI Fibroblast growth factor receptor 2 OS=Notophthalmus
viridescens OX=8316 GN=FGFR2 PE=2 SV=1
Length=729
Score = 157 bits (396), Expect = 4e-38, Method: Compositional matrix adjust.
Identities = 112/343 (33%), Positives = 167/343 (49%), Gaps = 45/343 (13%)
Query 862 ILRDLTRLQPHNLADVLT-VNPDSPASDPT-VFHKRYLKKIRDLGEGHFGKVSL---YCY 916
++R TRL +N +L V+ DP + + L + LGEG FG+V +
Sbjct 352 LVRITTRLSSNNDTHLLAGVSEYELPEDPKWEYPREKLTLGKPLGEGCFGQVVMAEAVGI 411
Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQ 975
D VAVK LK D + S E+++++ + H++II G C G L
Sbjct 412 DKDRPKDAATVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLY 469
Query 976 LVMEYVPLGSLRDYL-----------------PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+++EY G+LR+YL P + L+ Q+ GM YL +Q
Sbjct 470 VIVEYASKGNLREYLRTRRPPGMEYSFDINRIPEEQMTFKDLVSCTYQLARGMEYLASQK 529
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRDLAARNVL+ ++KI DFGLA+ + +YY+ +G PV W APE L + +
Sbjct 530 CIHRDLAARNVLVTETNVMKIADFGLARDI-NNIDYYKKTTNGRLPVKWMAPEALFDRVY 588
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+ SDVWSFGV ++E+ T L G + V L +LL+ G R+ +P
Sbjct 589 THQSDVWSFGVLMWEIFT--------------LGGSPYPGIPVEELFKLLKEGHRMDKPG 634
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPIL-----KTVHEKY 1176
C E+Y +M +CW S RPTF+ L+ L +T +E+Y
Sbjct 635 NCTNELYTMMTDCWRAVPSQRPTFKQLVEDLDRILTQTTNEEY 677
Score = 72.0 bits (175), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 65/265 (25%), Positives = 121/265 (46%), Gaps = 35/265 (13%)
Query 631 RDRGQEL-RVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
+DR ++ V +K+L D + D++ E + H ++ + G C + ++
Sbjct 413 KDRPKDAATVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIV 472
Query 688 EYVEHGPLDVWLRRER----------GHVP---MAWKMVVA--QQLASALSYLENKNLVH 732
EY G L +LR R +P M +K +V+ QLA + YL ++ +H
Sbjct 473 EYASKGNLREYLRTRRPPGMEYSFDINRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIH 532
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE--RIP--WLAPECLPG 786
++ RN+L+ + +K++D G+ + + ++ R+P W+APE L
Sbjct 533 RDLAARNVLVTETNV-------MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFD 585
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATL 844
+ + D W FG + EI G +P E + HR+ +P +C +L T+
Sbjct 586 RVYTHQS--DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPGNCTNELYTM 643
Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869
+ C P+QRP+F+ ++ DL R+
Sbjct 644 MTDCWRAVPSQRPTFKQLVEDLDRI 668
>sp|P43403|ZAP70_HUMAN Tyrosine-protein kinase ZAP-70 OS=Homo
sapiens OX=9606 GN=ZAP70 PE=1 SV=1
Length=619
Score = 155 bits (393), Expect = 4e-38, Method: Compositional matrix adjust.
Identities = 114/333 (34%), Positives = 157/333 (47%), Gaps = 39/333 (12%)
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899
++ TL S T EP R D R P + T +SP SDP + L
Sbjct 283 RIDTLNSDGYTPEPA-----RITSPDKPRPMPMD-----TSVYESPYSDPEELKDKKLFL 332
Query 900 IRD--------LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
RD LG G+FG V Y VA+K LK +E I+
Sbjct 333 KRDNLLIADIELGCGNFGSVRQGVYRMRKKQID--VAIKVLKQGTEKADTEEMMREAQIM 390
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICE 1009
L + +I++ G C+ + +L LVME G L +L R I ++ + Q+
Sbjct 391 HQLDNPYIVRLIGVCQAE---ALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSM 447
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
GM YL ++++HRDLAARNVLL N KI DFGL+KA+ YY R G P+ WYA
Sbjct 448 GMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYA 507
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PEC+ KF SDVWS+GVT++E L++ Q P K M + +E
Sbjct 508 PECINFRKFSSRSDVWSYGVTMWEALSY---GQKPYKK-----------MKGPEVMAFIE 553
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
+G+R+ P +CP E+Y LM +CW + RP F
Sbjct 554 QGKRMECPPECPPELYALMSDCWIYKWEDRPDF 586
Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 68/242 (28%), Positives = 110/242 (45%), Gaps = 20/242 (8%)
Query 631 RDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
R R +++ V +KVL A +M Q+ + ++ + GVC + ++V E
Sbjct 358 RMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVC-QAEALMLVMEM 416
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
GPL +L +R +P++ + Q++ + YLE KN VH ++ RN+LL
Sbjct 417 AGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLV------ 470
Query 750 GTSPFIKLSDPGV--GLGA-----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+ K+SD G+ LGA +R + W APEC+ S+ D W +G
Sbjct 471 -NRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECI--NFRKFSSRSDVWSYGV 527
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP-EPSC-PQLATLTSQCLTYEPTQRPSFR 860
T+ E G+ P + E F ++ R+ P C P+L L S C Y+ RP F
Sbjct 528 TMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFL 587
Query 861 TI 862
T+
Sbjct 588 TV 589
>sp|Q91286|FGFR2_PLEWA Fibroblast growth factor receptor 2 OS=Pleurodeles
waltl OX=8319 GN=FGFR2 PE=2 SV=1
Length=824
Score = 157 bits (398), Expect = 5e-38, Method: Compositional matrix adjust.
Identities = 113/347 (33%), Positives = 165/347 (48%), Gaps = 47/347 (14%)
Query 857 PSFRTILRDLTRLQPHNLADVLTVN-PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL-- 913
P R R L+ H LA V P+ P + + + L + LGEG FG+V +
Sbjct 440 PLVRITTRLLSNTDTHLLAGVSEYELPEDPKWE---YPRDKLTLGKPLGEGCFGQVVMAE 496
Query 914 -YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGE 971
D VAVK LK D + S E+++++ + H++II G C G
Sbjct 497 AVGIDKDRPKDAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDG- 555
Query 972 KSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQLLLFAQQICEGMAYL 1014
L +++EY G+LR+YL P + L+ Q+ GM YL
Sbjct 556 -PLYVIVEYASKGNLREYLRTRRPPGMEYSFDIFRIPEEQMTFKDLVSCTYQLARGMEYL 614
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+Q IHRDLAARNVL+ ++KI DFGLA+ + +YY+ +G PV W APE L
Sbjct 615 ASQKCIHRDLAARNVLVTETNVIKIADFGLARDI-NNIDYYKKTTNGRLPVKWMAPEALF 673
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ + SDVWSFGV ++E+ T L G + V L +LL+ G R+
Sbjct 674 DRVYTLQSDVWSFGVLMWEIFT--------------LGGSPYPGIPVEELFKLLKEGHRM 719
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL-----KTVHEKY 1176
+P C E+Y +M +CW S RPTF+ L+ L +T +E+Y
Sbjct 720 VKPGNCTNELYTMMTDCWRAVPSQRPTFKQLVEDLDRILTQTTNEEY 766
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 67/265 (25%), Positives = 123/265 (46%), Gaps = 35/265 (13%)
Query 631 RDRGQE-LRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
+DR ++ + V +K+L D + D++ E + H ++ + G C + ++
Sbjct 502 KDRPKDAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIV 561
Query 688 EYVEHGPLDVWLRRERG----------HVP---MAWKMVVA--QQLASALSYLENKNLVH 732
EY G L +LR R +P M +K +V+ QLA + YL ++ +H
Sbjct 562 EYASKGNLREYLRTRRPPGMEYSFDIFRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIH 621
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE--RIP--WLAPECLPG 786
++ RN+L+ + IK++D G+ + + ++ R+P W+APE L
Sbjct 622 RDLAARNVLVTETNV-------IKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFD 674
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATL 844
+L + D W FG + EI G +P E + HR+ +P +C +L T+
Sbjct 675 RVYTLQS--DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMVKPGNCTNELYTM 732
Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869
+ C P+QRP+F+ ++ DL R+
Sbjct 733 MTDCWRAVPSQRPTFKQLVEDLDRI 757
>sp|P21802|FGFR2_HUMAN Fibroblast growth factor receptor 2 OS=Homo
sapiens OX=9606 GN=FGFR2 PE=1 SV=1
Length=821
Score = 157 bits (397), Expect = 5e-38, Method: Compositional matrix adjust.
Identities = 104/311 (33%), Positives = 154/311 (50%), Gaps = 43/311 (14%)
Query 892 FHKRYLKKIRDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
F + L + LGEG FG+V + D VAVK LK D + S E+
Sbjct 476 FPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEM 535
Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------------- 990
++++ + H++II G C G L +++EY G+LR+YL
Sbjct 536 EMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPPGMEYSYDINRV 593
Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
P + L+ Q+ GM YL +Q IHRDLAARNVL+ + ++KI DFGLA+ +
Sbjct 594 PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDI-N 652
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
+YY+ +G PV W APE L + + + SDVWSFGV ++E+ T
Sbjct 653 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT-------------- 698
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
L G + V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L
Sbjct 699 LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLD 758
Query 1171 -----TVHEKY 1176
T +E+Y
Sbjct 759 RILTLTTNEEY 769
Score = 69.3 bits (168), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 64/265 (24%), Positives = 119/265 (45%), Gaps = 35/265 (13%)
Query 631 RDRGQE-LRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
+D+ +E + V +K+L D + D++ E + H ++ + G C + ++
Sbjct 505 KDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIV 564
Query 688 EYVEHGPLDVWLRRER----------GHVP---MAWKMVVA--QQLASALSYLENKNLVH 732
EY G L +LR R VP M +K +V+ QLA + YL ++ +H
Sbjct 565 EYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIH 624
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE--RIP--WLAPECLPG 786
++ RN+L+ + +K++D G+ + + ++ R+P W+APE L
Sbjct 625 RDLAARNVLVTENNV-------MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFD 677
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATL 844
+ + D W FG + EI G +P E + HR+ +P+ +L +
Sbjct 678 RVYTHQS--DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMM 735
Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869
C P+QRP+F+ ++ DL R+
Sbjct 736 MRDCWHAVPSQRPTFKQLVEDLDRI 760
>sp|P07949|RET_HUMAN Proto-oncogene tyrosine-protein kinase receptor
Ret OS=Homo sapiens OX=9606 GN=RET PE=1 SV=3
Length=1114
Score = 158 bits (400), Expect = 6e-38, Method: Compositional matrix adjust.
Identities = 106/310 (34%), Positives = 146/310 (47%), Gaps = 43/310 (14%)
Query 892 FHKRYLKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
F ++ L + LGEG FGKV + VAVK LK + P E ++
Sbjct 719 FPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNV 778
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------------------- 990
L+ + H H+IK G C G L L++EY GSLR +L
Sbjct 779 LKQVNHPHVIKLYGACSQDG--PLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSS 836
Query 991 -----PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
++ + L+ FA QI +GM YL +HRDLAARN+L+ R +KI DFGL+
Sbjct 837 SLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLS 896
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ V E Y + R G PV W A E L ++ + SDVWSFGV L+E++T
Sbjct 897 RDVYEEDSYVK-RSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVT--------- 946
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L G + RL LL+ G R+ RPD C E+Y LM CW+ E RP F ++
Sbjct 947 -----LGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 1001
Query 1166 IPILKTVHEK 1175
L+ + K
Sbjct 1002 SKDLEKMMVK 1011
Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 64/241 (27%), Positives = 104/241 (43%), Gaps = 40/241 (17%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------------ 707
+++ QV+H H+ ++G C + +++ EY ++G L +LR R P
Sbjct 777 NVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSS 836
Query 708 -----------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
M + A Q++ + YL LVH ++ RNIL +AEG +K
Sbjct 837 SLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNIL-----VAEGRK--MK 889
Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+SD G+ + V+R + W+A E L + +T D W FG L EI
Sbjct 890 ISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESL--FDHIYTTQSDVWSFGVLLWEIVTL 947
Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
G P P + + HR+ P+ ++ L QC EP +RP F I +DL +
Sbjct 948 GGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEK 1007
Query 869 L 869
+
Sbjct 1008 M 1008
>sp|P21803|FGFR2_MOUSE Fibroblast growth factor receptor 2 OS=Mus
musculus OX=10090 GN=Fgfr2 PE=1 SV=4
Length=821
Score = 157 bits (397), Expect = 6e-38, Method: Compositional matrix adjust.
Identities = 104/311 (33%), Positives = 154/311 (50%), Gaps = 43/311 (14%)
Query 892 FHKRYLKKIRDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
F + L + LGEG FG+V + D VAVK LK D + S E+
Sbjct 476 FPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEM 535
Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------------- 990
++++ + H++II G C G L +++EY G+LR+YL
Sbjct 536 EMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPPGMEYSYDINRV 593
Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
P + L+ Q+ GM YL +Q IHRDLAARNVL+ + ++KI DFGLA+ +
Sbjct 594 PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDI-N 652
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
+YY+ +G PV W APE L + + + SDVWSFGV ++E+ T
Sbjct 653 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT-------------- 698
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
L G + V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L
Sbjct 699 LGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLD 758
Query 1171 -----TVHEKY 1176
T +E+Y
Sbjct 759 RILTLTTNEEY 769
Score = 68.9 bits (167), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 64/265 (24%), Positives = 119/265 (45%), Gaps = 35/265 (13%)
Query 631 RDRGQE-LRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
+D+ +E + V +K+L D + D++ E + H ++ + G C + ++
Sbjct 505 KDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIV 564
Query 688 EYVEHGPLDVWLRRER----------GHVP---MAWKMVVA--QQLASALSYLENKNLVH 732
EY G L +LR R VP M +K +V+ QLA + YL ++ +H
Sbjct 565 EYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIH 624
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE--RIP--WLAPECLPG 786
++ RN+L+ + +K++D G+ + + ++ R+P W+APE L
Sbjct 625 RDLAARNVLVTE-------NNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFD 677
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATL 844
+ + D W FG + EI G +P E + HR+ +P+ +L +
Sbjct 678 RVYTHQS--DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMM 735
Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869
C P+QRP+F+ ++ DL R+
Sbjct 736 MRDCWHAVPSQRPTFKQLVEDLDRI 760
>sp|Q00655|KSYK_PIG Tyrosine-protein kinase SYK OS=Sus scrofa
OX=9823 GN=SYK PE=1 SV=1
Length=628
Score = 155 bits (391), Expect = 7e-38, Method: Compositional matrix adjust.
Identities = 101/289 (35%), Positives = 144/289 (50%), Gaps = 27/289 (9%)
Query 883 DSPASDPT------VFHKRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+SP +DP V+ R L + D LG G+FG V Y V + +A
Sbjct 342 ESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEA 401
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994
+ P + E ++++ L + +I++ G CE + S LVME LG L YL ++
Sbjct 402 N-DPALKDELLAEANVMQQLDNPYIVRMIGICEAE---SWMLVMEMAELGPLNKYLQQNR 457
Query 995 -IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ ++ Q+ GM YL +++HRDLAARNVLL KI DFGL+KA+
Sbjct 458 HVKDKNIIELVHQVSMGMKYLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN 517
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
YY+ + G PV WYAPEC+ YKF SDVWSFGV ++E ++ Q P
Sbjct 518 YYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSY---GQKPYRG------ 568
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
M ++ +LE+GER+ P CP E+Y LM CW + RP F
Sbjct 569 -----MKGSEVSAMLEKGERMGCPPGCPREMYELMTLCWTYDVENRPGF 612
Score = 87.0 bits (214), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 65/228 (29%), Positives = 107/228 (47%), Gaps = 25/228 (11%)
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
DP+ D LA A++M Q+ + ++ + G+C ++V E E GPL+ +L++ R
Sbjct 403 DPALKDELLA---EANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNR- 457
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
HV + + Q++ + YLE N VH ++ RN+LL T + K+SD G+
Sbjct 458 HVKDKNIIELVHQVSMGMKYLEECNFVHRDLAARNVLLV-------TQHYAKISDFGLS- 509
Query 765 GALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
AL +E + + W APEC+ S+ D W FG + E G+ P +
Sbjct 510 KALRADENYYKAQTHGKWPVKWYAPECI--NYYKFSSKSDVWSFGVLMWEAFSYGQKPYR 567
Query 817 SRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTI 862
SE ++ R+ P CP ++ L + C TY+ RP F +
Sbjct 568 GMKGSEVSAMLEKGERMGCPPGCPREMYELMTLCWTYDVENRPGFVAV 615
>sp|Q03351|NTRK3_RAT NT-3 growth factor receptor OS=Rattus norvegicus
OX=10116 GN=Ntrk3 PE=1 SV=2
Length=864
Score = 157 bits (397), Expect = 7e-38, Method: Compositional matrix adjust.
Identities = 114/334 (34%), Positives = 158/334 (47%), Gaps = 77/334 (23%)
Query 894 KRYLKKIRDLGEGHFGKVSLY-CYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+R + R+LGEG FGKV L CY+ PT D +VAVKALK D R +++E ++
Sbjct 535 RRDIVLKRELGEGAFGKVFLAECYNLSPTKDKM--LVAVKALK-DPTLAARKDFQREAEL 591
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------------- 994
L L HEHI+K+ G C D L +V EY+ G L +L H
Sbjct 592 LTNLQHEHIVKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKG 649
Query 995 -IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV----- 1048
+GL+Q+L A QI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V
Sbjct 650 ELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDY 709
Query 1049 ------------------------------PEGHEYYRVREDGDS---PVFWYAPECLKE 1075
P G+++ E G P+ W PE +
Sbjct 710 YREGPYQKGPFSVSWQQQRLAASAASTLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMY 769
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+E+ T+ + P Q++ + E + +G L
Sbjct 770 RKFTTESDVWSFGVILWEIFTY---GKQP-----------WFQLSNTEVIECITQGRVLE 815
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
RP CP EVY +M CW+ E R + + IL
Sbjct 816 RPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 849
Score = 67.0 bits (162), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 72/305 (24%), Positives = 118/305 (39%), Gaps = 74/305 (24%)
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
L P +D+ + V +K L F A L++ + H H+ +GVC G IMV
Sbjct 560 LSPTKDK---MLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMV 616
Query 687 TEYVEHGPLDVWL---------------RRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
EY++HG L+ +L R+ +G + ++ + +A Q+AS + YL +++ V
Sbjct 617 FEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFV 676
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP---------- 777
H ++ RN L+ G + +K+ D G+ S RE ++ P
Sbjct 677 HRDLATRNCLV-------GANLLVKIGDFGMSRDVYSTDYYREGPYQKGPFSVSWQQQRL 729
Query 778 -------------------------------WLAPECLPGGANSLSTAMDKWGFGATLLE 806
W+ PE + +T D W FG L E
Sbjct 730 AASAASTLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGVILWE 787
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILR 864
I G+ P S +E + L P CP ++ + C EP QR + + I +
Sbjct 788 IFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYK 847
Query 865 DLTRL 869
L L
Sbjct 848 ILHAL 852
>sp|Q91288|FGFR4_PLEWA Fibroblast growth factor receptor 4 OS=Pleurodeles
waltl OX=8319 GN=FGFR4 PE=2 SV=1
Length=822
Score = 157 bits (396), Expect = 8e-38, Method: Compositional matrix adjust.
Identities = 106/319 (33%), Positives = 156/319 (49%), Gaps = 42/319 (13%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADCGPQ 939
D P F + L + LGEG FG+V Y + VA+K +K +
Sbjct 472 DLPLDSKWEFPRERLVLGKPLGEGCFGQVVRAEAYGINKDQPDKAITVAIKIVKDKGTDK 531
Query 940 HRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------- 990
S E+++++ + H++II G C G L +++EY G+LR++L
Sbjct 532 ELSDLISEMELMKLMGKHKNIINLLGVCTQDG--PLYMIVEYASKGNLREFLRARRPPSP 589
Query 991 ---------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
P + L+ + Q+ GMAYL ++ IHRDLAARNVL+ + ++KI D
Sbjct 590 DYTFDMTKVPEEQLSFQDLVSCSYQVARGMAYLESKRCIHRDLAARNVLVTGENVMKIAD 649
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLA+ V + +YY+ +G PV W APE L + + + SDVWSFGV +E+ T
Sbjct 650 FGLARGVHD-IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLTWEIFT----- 703
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
L G + V L +LL G R+ +P C E+Y LM+ CW S RPT
Sbjct 704 ---------LGGSPYPGIPVEELFKLLREGHRMDKPSNCTHELYMLMRECWHAAPSQRPT 754
Query 1162 FENLIP----ILKTVHEKY 1176
F+ L+ IL TV E+Y
Sbjct 755 FKQLVETLDRILATVAEEY 773
Score = 69.7 bits (169), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 65/260 (25%), Positives = 116/260 (45%), Gaps = 34/260 (13%)
Query 635 QELRVVLKVLDPSHHDIALA-FYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEH 692
+ + V +K++ D L+ LM + H ++ + GVC + M+ EY
Sbjct 515 KAITVAIKIVKDKGTDKELSDLISEMELMKLMGKHKNIINLLGVCTQDGPLYMIVEYASK 574
Query 693 GPLDVWLRRERGHVP-------------MAWKMVVA--QQLASALSYLENKNLVHGNVCG 737
G L +LR R P ++++ +V+ Q+A ++YLE+K +H ++
Sbjct 575 GNLREFLRARRPPSPDYTFDMTKVPEEQLSFQDLVSCSYQVARGMAYLESKRCIHRDLAA 634
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSL 791
RN+L+ + +K++D G+ G ++ R+P W+APE L +
Sbjct 635 RNVLVTGENV-------MKIADFGLARGVHDIDYYKKTSNGRLPVKWMAPEALFDRVYTH 687
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCL 849
+ D W FG EI G +P E + HR+ +PS C +L L +C
Sbjct 688 QS--DVWSFGVLTWEIFTLGGSPYPGIPVEELFKLLREGHRMDKPSNCTHELYMLMRECW 745
Query 850 TYEPTQRPSFRTILRDLTRL 869
P+QRP+F+ ++ L R+
Sbjct 746 HAAPSQRPTFKQLVETLDRI 765
>sp|Q5RB22|ERBB3_PONAB Receptor tyrosine-protein kinase erbB-3
OS=Pongo abelii OX=9601 GN=ERBB3 PE=2 SV=1
Length=1342
Score = 158 bits (400), Expect = 8e-38, Method: Compositional matrix adjust.
Identities = 98/277 (35%), Positives = 148/277 (53%), Gaps = 20/277 (7%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+F + LKK++ LG G FG V + P + V +K ++ G Q +
Sbjct 703 IFKETELKKLKVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLA 762
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQIC 1008
+ +L H HI++ G C SLQLV +Y+PLGSL D++ +H ++G LL + QI
Sbjct 763 IGSLDHAHIVRLLGLCPG---SSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIA 819
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+GM YL +HR+LAARNVLL + V++ DFG+A +P + E +P+ W
Sbjct 820 KGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDKQLLYSE-AKTPIKWM 878
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A E + K+ + SDVWS+GVT++EL+T + P L L + +LL
Sbjct 879 ALESIHFGKYTHQSDVWSYGVTVWELMTF----GAEPYAGLRLA----------EVPDLL 924
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
E+GERL +P C +VY +M CW + + RPTF+ L
Sbjct 925 EKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKEL 961
Score = 64.7 bits (156), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 73/298 (24%), Positives = 121/298 (41%), Gaps = 49/298 (16%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL- 644
+ E+ +L LG G V++G EG E +P V +KV+
Sbjct 706 ETELKKLKVLGSGVFGTVHKGVWIPEG-----------ESIKIP---------VCIKVIE 745
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D S A + + + H H+ + G+C G +VT+Y+ G L +R+ RG
Sbjct 746 DKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLC-PGSSLQLVTQYLPLGSLLDHVRQHRG 804
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEGTSPFIK 756
+ + Q+A + YLE +VH N+ RN+LL A G+A+ P K
Sbjct 805 ALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDK 864
Query 757 LSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
L E I W+A E + G + + D W +G T+ E+ G P
Sbjct 865 ---------QLLYSEAKTPIKWMALESIHFGKYTHQS--DVWSYGVTVWELMTFGAEPYA 913
Query 817 SRSPSEKEHFYQRQHRLPEPSCPQLATL-----TSQCLTYEPTQRPSFRTILRDLTRL 869
+E ++ RL + PQ+ T+ +C + RP+F+ + + TR+
Sbjct 914 GLRLAEVPDLLEKGERLAQ---PQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRM 968
>sp|Q61851|FGFR3_MOUSE Fibroblast growth factor receptor 3 OS=Mus
musculus OX=10090 GN=Fgfr3 PE=1 SV=1
Length=801
Score = 157 bits (396), Expect = 8e-38, Method: Compositional matrix adjust.
Identities = 101/293 (34%), Positives = 146/293 (50%), Gaps = 37/293 (13%)
Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956
+ LGEG FG+V + D VAVK LK D + S E+++++ + H
Sbjct 470 KPLGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKH 529
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999
++II G C G L +++EY G+LR++L P +
Sbjct 530 KNIINLLGACTQGG--PLYVLVEYAAKGNLREFLRARRPPGMDYSFDACRLPEEQLTCKD 587
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
L+ A Q+ GM YL +Q IHRDLAARNVL+ D ++KI DFGLA+ V +YY+
Sbjct 588 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDV-HNLDYYKKTT 646
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
+G PV W APE L + + + SDVWSFGV L+E+ T S P EL
Sbjct 647 NGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTPGGPSPYPGIPVEELF------- 699
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+LL+ G R+ +P C ++Y +M+ CW S RPTF+ L+ L +
Sbjct 700 ------KLLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRI 746
Score = 62.0 bits (149), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 66/266 (25%), Positives = 118/266 (44%), Gaps = 36/266 (14%)
Query 631 RDR-GQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
+DR + + V +K+L D + D++ E + H ++ + G C +G ++
Sbjct 490 KDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLV 549
Query 688 EYVEHGPLDVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVH 732
EY G L +LR R +P + K +V A Q+A + YL ++ +H
Sbjct 550 EYAAKGNLREFLRARRPPGMDYSFDACRLPEEQLTCKDLVSCAYQVARGMEYLASQKCIH 609
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPG 786
++ RN+L+ + +K++D G+ + ++ R+P W+APE L
Sbjct 610 RDLAARNVLVTEDNV-------MKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFD 662
Query 787 GANSLSTAMDKWGFGATLLEICF-DGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLAT 843
+ + D W FG L EI G +P E + HR+ +P SC L
Sbjct 663 RVYTHQS--DVWSFGVLLWEIFTPGGPSPYPGIPVEELFKLLKEGHRMDKPASCTHDLYM 720
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869
+ +C P+QRP+F+ ++ DL R+
Sbjct 721 IMRECWHAVPSQRPTFKQLVEDLDRI 746
>sp|Q91285|FGFR1_PLEWA Fibroblast growth factor receptor 1 OS=Pleurodeles
waltl OX=8319 GN=FGFR1 PE=2 SV=1
Length=816
Score = 156 bits (395), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 102/293 (35%), Positives = 150/293 (51%), Gaps = 38/293 (13%)
Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956
+ LGEG FG+V + D VAVK LK+D + S E+++++ + H
Sbjct 478 KPLGEGCFGQVVMGEAIGLDKEKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKH 537
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------------PRHS----IGLAQ 999
++II G C G L +++EY G+LR+YL P H +
Sbjct 538 KNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPPGMEYCYNPIHVSKDMLSFKD 595
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+
Sbjct 596 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDSVMKIADFGLARDI-HHIDYYKKTT 654
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
+G PV W APE L + + + SDVWSFGV L+E+ T L G +
Sbjct 655 NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGV 700
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L +
Sbjct 701 PVEELFKLLKEGHRMDKPGNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 753
Score = 68.2 bits (165), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 66/272 (24%), Positives = 117/272 (43%), Gaps = 37/272 (14%)
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680
+D E P +R ++ V + D + D++ E + H ++ + G C +
Sbjct 496 LDKEKP-----NRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQD 550
Query 681 PENIMVTEYVEHGPLDVWLRRERG----------HVP---MAWKMVV--AQQLASALSYL 725
++ EY G L +LR R HV +++K +V A Q+A + YL
Sbjct 551 GPLYVIVEYASKGNLREYLRARRPPGMEYCYNPIHVSKDMLSFKDLVSCAYQVARGMEYL 610
Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WL 779
+K +H ++ RN+L+ +K++D G+ ++ R+P W+
Sbjct 611 ASKKCIHRDLAARNVLVTE-------DSVMKIADFGLARDIHHIDYYKKTTNGRLPVKWM 663
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838
APE L + + D W FG L EI G +P E + HR+ +P +C
Sbjct 664 APEALFDRIYTHQS--DVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPGNC 721
Query 839 P-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+L + C P+QRP+F+ ++ DL R+
Sbjct 722 TNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 753
>sp|Q62799|ERBB3_RAT Receptor tyrosine-protein kinase erbB-3 OS=Rattus
norvegicus OX=10116 GN=Erbb3 PE=1 SV=3
Length=1339
Score = 157 bits (398), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 96/277 (35%), Positives = 148/277 (53%), Gaps = 20/277 (7%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+F + L+K++ LG G FG V + P + V +K ++ G Q +
Sbjct 701 IFKETELRKLKVLGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLA 760
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQIC 1008
+ +L H HI++ G C SLQLV +Y+PLGSL D++ +H ++G LL + QI
Sbjct 761 VGSLDHAHIVRLLGLCPG---SSLQLVTQYLPLGSLLDHVKQHRETLGPQLLLNWGVQIA 817
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+GM YL +HRDLA RNV+L + V++ DFG+A +P + + + +P+ W
Sbjct 818 KGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADLLPPDDKQL-LHSEAKTPIKWM 876
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A E + K+ + SDVWS+GVT++EL+T + P L L I +LL
Sbjct 877 ALESIHFGKYTHQSDVWSYGVTVWELMTF----GAEPYAGLRLAEIP----------DLL 922
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
E+GERL +P C +VY +M CW + + RPTF+ L
Sbjct 923 EKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKEL 959
Score = 60.5 bits (145), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 77/332 (23%), Positives = 136/332 (41%), Gaps = 53/332 (16%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL- 644
+ E+ +L LG G V++G EG E +P V +KV+
Sbjct 704 ETELRKLKVLGSGVFGTVHKGIWIPEG-----------ESIKIP---------VCIKVIE 743
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D S A + + + H H+ + G+C G +VT+Y+ G L +++ R
Sbjct 744 DKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLC-PGSSLQLVTQYLPLGSLLDHVKQHRE 802
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEGTSPFIK 756
+ + Q+A + YLE ++VH ++ RN++L A G+A+ P K
Sbjct 803 TLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADLLPPDDK 862
Query 757 LSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
L E I W+A E + G + + D W +G T+ E+ G P
Sbjct 863 ---------QLLHSEAKTPIKWMALESIHFGKYTHQS--DVWSYGVTVWELMTFGAEPYA 911
Query 817 SRSPSEKEHFYQRQHRLPEPSCPQLATL-----TSQCLTYEPTQRPSFRTILRDLTRLQ- 870
+E ++ RL + PQ+ T+ +C + RP+F+ + + TR+
Sbjct 912 GLRLAEIPDLLEKGERLAQ---PQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMAR 968
Query 871 --PHNLADVLTVNPDS-PASDPTVFHKRYLKK 899
P L P + PA++P+V + L++
Sbjct 969 DPPRYLVIKRASGPGTPPAAEPSVLTTKELQE 1000
>sp|Q24488|ROR1_DROME Tyrosine-protein kinase transmembrane receptor
Ror OS=Drosophila melanogaster OX=7227 GN=Ror PE=1 SV=1
Length=685
Score = 155 bits (391), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 104/281 (37%), Positives = 150/281 (53%), Gaps = 24/281 (9%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +LGEG FGKV N T VA+KALK + + + +K+EI+++ L H++I
Sbjct 413 LEELGEGAFGKVYKGQLLQPNKTTI-TVAIKALKENASVKTQQDFKREIELISDLKHQNI 471
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQL--LLFAQQICEGMAY 1013
+ G ++ + ++ EY+ G L ++L P L+QL L A QI EGM Y
Sbjct 472 VCILGVVLNK--EPYCMLFEYMANGDLHEFLISNSPTEGKSLSQLEFLQIALQISEGMQY 529
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
L A HY+HRDLAARN L++ +VKI DFGL++ + +YYRV+ PV W E +
Sbjct 530 LSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSS-DYYRVQSKSLLPVRWMPSESI 588
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
KF SDVWSFGV L+E+ ++ P F Q + ++R +L
Sbjct 589 LYGKFTTESDVWSFGVVLWEIYSY---GMQPYYGFSN-----QEVINLIRSRQL------ 634
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
L P+ CP VY LM CW ++ RPTF ++ LKT HE
Sbjct 635 LSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRLKTWHE 675
Score = 59.7 bits (143), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 69/289 (24%), Positives = 119/289 (41%), Gaps = 43/289 (15%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-D 645
+++ L LG+G VY+G+L L P + + V +K L +
Sbjct 408 QDVEFLEELGEGAFGKVYKGQL------------------LQPNK---TTITVAIKALKE 446
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR---- 701
+ F L+S + H ++ + GV + M+ EY+ +G L +L
Sbjct 447 NASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSPT 506
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
E + + +A Q++ + YL + VH ++ RN L+ GL +K+SD G
Sbjct 507 EGKSLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNE-GLV------VKISDFG 559
Query 762 VGLGALSRE-ERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
+ S + RV+ + W+ E + G +T D W FG L EI G P
Sbjct 560 LSRDIYSSDYYRVQSKSLLPVRWMPSESILYG--KFTTESDVWSFGVVLWEIYSYGMQPY 617
Query 816 QSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
S E + + + L P +CP + +L +C + +RP+F I
Sbjct 618 YGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDI 666
>sp|Q64725|KSYK_RAT Tyrosine-protein kinase SYK OS=Rattus norvegicus
OX=10116 GN=Syk PE=1 SV=1
Length=629
Score = 154 bits (389), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 101/289 (35%), Positives = 143/289 (49%), Gaps = 27/289 (9%)
Query 883 DSPASDPT------VFHKRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+SP +DP V+ R L + D LG G+FG V Y V + +A
Sbjct 343 ESPYADPEEIRPKEVYLDRKLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEA 402
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994
+ P + E ++++ L + +I++ G CE + S LVME G L YL ++
Sbjct 403 N-DPALKDELLAEANVMQQLDNPYIVRMIGICEAE---SWMLVMEMAAWGPLNKYLQQNR 458
Query 995 -IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
I ++ Q+ GM YL +++HRDLAARNVLL KI DFGL+KA+
Sbjct 459 HIKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN 518
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
YY+ + G PV WYAPEC+ +KF SDVWSFGV ++E ++ Q P
Sbjct 519 YYKAQTHGKWPVKWYAPECINYFKFSSKSDVWSFGVLMWEAFSY---GQKPYRG------ 569
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
M +T +LE+GER+ P CP E+Y LM CW + RP F
Sbjct 570 -----MKGSEVTAMLEKGERMGCPPGCPREMYDLMFLCWTYDVENRPGF 613
Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 63/228 (28%), Positives = 105/228 (46%), Gaps = 25/228 (11%)
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
DP+ D LA A++M Q+ + ++ + G+C ++V E GPL+ +L++ R
Sbjct 404 DPALKDELLA---EANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAAWGPLNKYLQQNR- 458
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
H+ + + Q++ + YLE N VH ++ RN+LL T + K+SD G+
Sbjct 459 HIKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLV-------TQHYAKISDFGLS- 510
Query 765 GALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
AL +E + + W APEC+ S+ D W FG + E G+ P +
Sbjct 511 KALRADENYYKAQTHGKWPVKWYAPECI--NYFKFSSKSDVWSFGVLMWEAFSYGQKPYR 568
Query 817 SRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTI 862
SE ++ R+ P CP ++ L C TY+ RP F +
Sbjct 569 GMKGSEVTAMLEKGERMGCPPGCPREMYDLMFLCWTYDVENRPGFAAV 616
>sp|Q03364|FGFR2_XENLA Fibroblast growth factor receptor 2 OS=Xenopus
laevis OX=8355 GN=fgfr2 PE=2 SV=1
Length=813
Score = 156 bits (394), Expect = 1e-37, Method: Compositional matrix adjust.
Identities = 104/311 (33%), Positives = 154/311 (50%), Gaps = 43/311 (14%)
Query 892 FHKRYLKKIRDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
F + L + LGEG FG+V + D VAVK LK + + + E+
Sbjct 466 FSRDKLTLGKPLGEGCFGQVVMAEALGIDKERPKESVTVAVKMLKDNATEKDLADLVSEM 525
Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------------- 990
++++ + H++II G C G +L +++EY G+LR YL
Sbjct 526 EMMKMIGKHKNIINLLGACTQGG--TLYVIVEYAAKGNLRQYLRARRPLEMEYSFDVTRV 583
Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
P + L+ QI GM YL +Q IHRDLAARNVL+ + ++KI DFGLA+ V
Sbjct 584 PDEQMTFKDLVSCTYQIARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDV-N 642
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
+YY+ +G PV W APE L + + + SDVWSFGV ++E+ T
Sbjct 643 NIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT-------------- 688
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
L G + V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L
Sbjct 689 LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAIPSHRPTFKQLVEDLD 748
Query 1171 -----TVHEKY 1176
T +E+Y
Sbjct 749 RILTLTTNEEY 759
Score = 67.8 bits (164), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 61/260 (23%), Positives = 114/260 (44%), Gaps = 34/260 (13%)
Query 635 QELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
+ + V +K+L + + D+A E + H ++ + G C +G ++ EY
Sbjct 500 ESVTVAVKMLKDNATEKDLADLVSEMEMMKMIGKHKNIINLLGACTQGGTLYVIVEYAAK 559
Query 693 GPLDVWLRRER----------GHVP---MAWKMVVA--QQLASALSYLENKNLVHGNVCG 737
G L +LR R VP M +K +V+ Q+A + YL ++ +H ++
Sbjct 560 GNLRQYLRARRPLEMEYSFDVTRVPDEQMTFKDLVSCTYQIARGMEYLASQKCIHRDLAA 619
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGANSL 791
RN+L+ + +K++D G+ + ++ R+P W+APE L +
Sbjct 620 RNVLVTENNV-------MKIADFGLARDVNNIDYYKKTSNGRLPVKWMAPEALFDRVYTH 672
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATLTSQCL 849
+ D W FG + EI G +P E + HR+ +P+ +L + C
Sbjct 673 QS--DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCW 730
Query 850 TYEPTQRPSFRTILRDLTRL 869
P+ RP+F+ ++ DL R+
Sbjct 731 HAIPSHRPTFKQLVEDLDRI 750
>sp|P21860|ERBB3_HUMAN Receptor tyrosine-protein kinase erbB-3
OS=Homo sapiens OX=9606 GN=ERBB3 PE=1 SV=1
Length=1342
Score = 157 bits (397), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 97/277 (35%), Positives = 148/277 (53%), Gaps = 20/277 (7%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+F + L+K++ LG G FG V + P + V +K ++ G Q +
Sbjct 703 IFKETELRKLKVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLA 762
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQIC 1008
+ +L H HI++ G C SLQLV +Y+PLGSL D++ +H ++G LL + QI
Sbjct 763 IGSLDHAHIVRLLGLCPG---SSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIA 819
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+GM YL +HR+LAARNVLL + V++ DFG+A +P + E +P+ W
Sbjct 820 KGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDKQLLYSE-AKTPIKWM 878
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A E + K+ + SDVWS+GVT++EL+T + P L L + +LL
Sbjct 879 ALESIHFGKYTHQSDVWSYGVTVWELMTF----GAEPYAGLRLA----------EVPDLL 924
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
E+GERL +P C +VY +M CW + + RPTF+ L
Sbjct 925 EKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKEL 961
Score = 64.3 bits (155), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 73/298 (24%), Positives = 121/298 (41%), Gaps = 49/298 (16%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL- 644
+ E+ +L LG G V++G EG E +P V +KV+
Sbjct 706 ETELRKLKVLGSGVFGTVHKGVWIPEG-----------ESIKIP---------VCIKVIE 745
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D S A + + + H H+ + G+C G +VT+Y+ G L +R+ RG
Sbjct 746 DKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLC-PGSSLQLVTQYLPLGSLLDHVRQHRG 804
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEGTSPFIK 756
+ + Q+A + YLE +VH N+ RN+LL A G+A+ P K
Sbjct 805 ALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDK 864
Query 757 LSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
L E I W+A E + G + + D W +G T+ E+ G P
Sbjct 865 ---------QLLYSEAKTPIKWMALESIHFGKYTHQS--DVWSYGVTVWELMTFGAEPYA 913
Query 817 SRSPSEKEHFYQRQHRLPEPSCPQLATL-----TSQCLTYEPTQRPSFRTILRDLTRL 869
+E ++ RL + PQ+ T+ +C + RP+F+ + + TR+
Sbjct 914 GLRLAEVPDLLEKGERLAQ---PQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRM 968
>sp|Q61526|ERBB3_MOUSE Receptor tyrosine-protein kinase erbB-3
OS=Mus musculus OX=10090 GN=Erbb3 PE=1 SV=2
Length=1339
Score = 157 bits (397), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 96/277 (35%), Positives = 148/277 (53%), Gaps = 20/277 (7%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+F + L+K++ LG G FG V + P + V +K ++ G Q +
Sbjct 701 IFKETELRKLKVLGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLA 760
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQIC 1008
+ +L H HI++ G C SLQLV +Y+PLGSL D++ +H ++G LL + QI
Sbjct 761 VGSLDHAHIVRLLGLCPG---SSLQLVTQYLPLGSLLDHVRQHRETLGPQLLLNWGVQIA 817
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+GM YL +HRDLA RNV+L + V++ DFG+A +P + + + +P+ W
Sbjct 818 KGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADLLPPDDKQL-LHSEAKTPIKWM 876
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A E + K+ + SDVWS+GVT++EL+T + P L L I +LL
Sbjct 877 ALESIHFGKYTHQSDVWSYGVTVWELMTF----GAEPYAGLRLAEIP----------DLL 922
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
E+GERL +P C +VY +M CW + + RPTF+ L
Sbjct 923 EKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKEL 959
Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 77/331 (23%), Positives = 133/331 (40%), Gaps = 53/331 (16%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL- 644
+ E+ +L LG G V++G EG E +P V +KV+
Sbjct 704 ETELRKLKVLGSGVFGTVHKGIWIPEG-----------ESIKIP---------VCIKVIE 743
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D S A + + + H H+ + G+C G +VT+Y+ G L +R+ R
Sbjct 744 DKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLC-PGSSLQLVTQYLPLGSLLDHVRQHRE 802
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEGTSPFIK 756
+ + Q+A + YLE ++VH ++ RN++L A G+A+ P K
Sbjct 803 TLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADLLPPDDK 862
Query 757 LSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
L E I W+A E + G + + D W +G T+ E+ G P
Sbjct 863 ---------QLLHSEAKTPIKWMALESIHFGKYTHQS--DVWSYGVTVWELMTFGAEPYA 911
Query 817 SRSPSEKEHFYQRQHRLPEPSCPQLATL-----TSQCLTYEPTQRPSFRTILRDLTRLQ- 870
+E ++ RL + PQ+ T+ +C + RP+F+ + + TR+
Sbjct 912 GLRLAEIPDLLEKGERLAQ---PQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMAR 968
Query 871 --PHNLADVLTVNPD-SPASDPTVFHKRYLK 898
P L P PA++P+ + L+
Sbjct 969 DPPRYLVIKRASGPGIPPAAEPSALSTKELQ 999
>sp|P55245|EGFR_MACMU Epidermal growth factor receptor OS=Macaca
mulatta OX=9544 GN=EGFR PE=2 SV=2
Length=1210
Score = 157 bits (396), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 109/308 (35%), Positives = 160/308 (52%), Gaps = 24/308 (8%)
Query 864 RDLTRL-QPHNLADVLTVNPDSPASDPT-VFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
R L RL Q L + LT + ++P + + KKI+ LG G FG V + P +
Sbjct 677 RTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGE 736
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VA+K L+ P+ E ++ ++ + H+ + G C ++QL+ + +
Sbjct 737 KVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLM 793
Query 982 PLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P G L DY+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI
Sbjct 794 PFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKI 853
Query 1040 GDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
DFGLAK + E EY+ E G P+ W A E + + + SDVWS+GVT++EL+T
Sbjct 854 TDFGLAKLLGAEEKEYH--AEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTF- 910
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
S P GI + ++ +LE+GERLP+P C +VY +M CW +A
Sbjct 911 ---GSKPYD-----GIPASE-----ISSILEKGERLPQPPICTIDVYMIMVKCWMIDADS 957
Query 1159 RPTFENLI 1166
RP F LI
Sbjct 958 RPKFRELI 965
Score = 72.0 bits (175), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 52/221 (24%), Positives = 105/221 (48%), Gaps = 18/221 (8%)
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
+ A +M+ V + H+ + G+C+ ++T+ + G L ++R + ++ + +
Sbjct 761 DEAYVMASVDNPHVCRLLGICLTSTVQ-LITQLMPFGCLLDYVREHKDNIGSQYLLNWCV 819
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE 774
Q+A ++YLE++ LVH ++ RN+L+ T +K++D G+ LGA +E E
Sbjct 820 QIAKGMNYLEDRRLVHRDLAARNVLVK-------TPQHVKITDFGLAKLLGAEEKEYHAE 872
Query 775 R----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
I W+A E + + + D W +G T+ E+ G P SE ++
Sbjct 873 GGKVPIKWMALESILHRIYTHQS--DVWSYGVTVWELMTFGSKPYDGIPASEISSILEKG 930
Query 831 HRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869
RLP+P + + +C + RP FR ++ + +++
Sbjct 931 ERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKM 971
>sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo
sapiens OX=9606 GN=EGFR PE=1 SV=2
Length=1210
Score = 157 bits (396), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 109/308 (35%), Positives = 160/308 (52%), Gaps = 24/308 (8%)
Query 864 RDLTRL-QPHNLADVLTVNPDSPASDPT-VFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
R L RL Q L + LT + ++P + + KKI+ LG G FG V + P +
Sbjct 677 RTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGE 736
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VA+K L+ P+ E ++ ++ + H+ + G C ++QL+ + +
Sbjct 737 KVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLM 793
Query 982 PLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P G L DY+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI
Sbjct 794 PFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKI 853
Query 1040 GDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
DFGLAK + E EY+ E G P+ W A E + + + SDVWS+GVT++EL+T
Sbjct 854 TDFGLAKLLGAEEKEYH--AEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTF- 910
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
S P GI + ++ +LE+GERLP+P C +VY +M CW +A
Sbjct 911 ---GSKPYD-----GIPASE-----ISSILEKGERLPQPPICTIDVYMIMVKCWMIDADS 957
Query 1159 RPTFENLI 1166
RP F LI
Sbjct 958 RPKFRELI 965
Score = 71.6 bits (174), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 52/221 (24%), Positives = 105/221 (48%), Gaps = 18/221 (8%)
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
+ A +M+ V + H+ + G+C+ ++T+ + G L ++R + ++ + +
Sbjct 761 DEAYVMASVDNPHVCRLLGICLTSTVQ-LITQLMPFGCLLDYVREHKDNIGSQYLLNWCV 819
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE 774
Q+A ++YLE++ LVH ++ RN+L+ T +K++D G+ LGA +E E
Sbjct 820 QIAKGMNYLEDRRLVHRDLAARNVLVK-------TPQHVKITDFGLAKLLGAEEKEYHAE 872
Query 775 R----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
I W+A E + + + D W +G T+ E+ G P SE ++
Sbjct 873 GGKVPIKWMALESILHRIYTHQS--DVWSYGVTVWELMTFGSKPYDGIPASEISSILEKG 930
Query 831 HRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869
RLP+P + + +C + RP FR ++ + +++
Sbjct 931 ERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKM 971
>sp|Q8JG38|FGFR2_DANRE Fibroblast growth factor receptor 2 OS=Danio
rerio OX=7955 GN=fgfr2 PE=1 SV=1
Length=817
Score = 155 bits (393), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 104/302 (34%), Positives = 153/302 (51%), Gaps = 38/302 (13%)
Query 892 FHKRYLKKIRDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
F + L + LGEG FG+V + D VAVK LK D + S E+
Sbjct 472 FSRDKLTLGKPLGEGCFGQVVMAEALGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEM 531
Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-------RHSIGLAQ- 999
++++ + H++II G C G L +++EY G+LR+YL +S +A+
Sbjct 532 EMMKMIGRHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPPGMEYSYDIARV 589
Query 1000 ---------LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
L+ Q+ GM YL +Q IHRDLAARNVL+ ++KI DFGLA+ V
Sbjct 590 SDEPLTFKDLVSCTYQVARGMEYLASQKCIHRDLAARNVLVTESNVMKIADFGLARDV-H 648
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
+YY+ +G PV W APE L + + + SDVWSFGV ++E+ T
Sbjct 649 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT-------------- 694
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
L G + V L +LL+ G R+ +P C E+Y +MK+CW +S RPTF+ L+ L
Sbjct 695 LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMKDCWHAISSHRPTFKQLVEDLD 754
Query 1171 TV 1172
+
Sbjct 755 RI 756
Score = 63.9 bits (154), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 60/265 (23%), Positives = 115/265 (43%), Gaps = 35/265 (13%)
Query 631 RDRGQE-LRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
+D+ +E + V +K+L D + D++ E + H ++ + G C + ++
Sbjct 501 KDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGRHKNIINLLGACTQDGPLYVIV 560
Query 688 EYVEHGPLDVWLRRER-------------GHVPMAWKMVVA--QQLASALSYLENKNLVH 732
EY G L +LR R P+ +K +V+ Q+A + YL ++ +H
Sbjct 561 EYASKGNLREYLRARRPPGMEYSYDIARVSDEPLTFKDLVSCTYQVARGMEYLASQKCIH 620
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPG 786
++ RN+L+ S +K++D G+ + ++ R+P W+APE L
Sbjct 621 RDLAARNVLVTE-------SNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFD 673
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATL 844
+ + D W FG + EI G +P E + HR+ +P+ +L +
Sbjct 674 RVYTHQS--DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMM 731
Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869
C + RP+F+ ++ DL R+
Sbjct 732 MKDCWHAISSHRPTFKQLVEDLDRI 756
>sp|Q01279|EGFR_MOUSE Epidermal growth factor receptor OS=Mus
musculus OX=10090 GN=Egfr PE=1 SV=1
Length=1210
Score = 156 bits (395), Expect = 3e-37, Method: Compositional matrix adjust.
Identities = 109/308 (35%), Positives = 160/308 (52%), Gaps = 24/308 (8%)
Query 864 RDLTRL-QPHNLADVLTVNPDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
R L RL Q L + LT + ++P + + + KKI+ LG G FG V + P +
Sbjct 679 RTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGE 738
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VA+K L+ P+ E ++ ++ + H+ + G C ++QL+ + +
Sbjct 739 KVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLM 795
Query 982 PLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P G L DY+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI
Sbjct 796 PYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKI 855
Query 1040 GDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
DFGLAK + E EY+ E G P+ W A E + + + SDVWS+GVT++EL+T
Sbjct 856 TDFGLAKLLGAEEKEYH--AEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTF- 912
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
S P GI ++ +LE+GERLP+P C +VY +M CW +A
Sbjct 913 ---GSKPYD-----GIPASD-----ISSILEKGERLPQPPICTIDVYMIMVKCWMIDADS 959
Query 1159 RPTFENLI 1166
RP F LI
Sbjct 960 RPKFRELI 967
Score = 72.4 bits (176), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 51/221 (23%), Positives = 105/221 (48%), Gaps = 18/221 (8%)
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
+ A +M+ V + H+ + G+C+ ++T+ + +G L ++R + ++ + +
Sbjct 763 DEAYVMASVDNPHVCRLLGICLTSTVQ-LITQLMPYGCLLDYVREHKDNIGSQYLLNWCV 821
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE 774
Q+A ++YLE++ LVH ++ RN+L+ T +K++D G+ LGA +E E
Sbjct 822 QIAKGMNYLEDRRLVHRDLAARNVLVK-------TPQHVKITDFGLAKLLGAEEKEYHAE 874
Query 775 R----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
I W+A E + + D W +G T+ E+ G P S+ ++
Sbjct 875 GGKVPIKWMALESIL--HRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASDISSILEKG 932
Query 831 HRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869
RLP+P + + +C + RP FR ++ + +++
Sbjct 933 ERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELILEFSKM 973
>sp|Q9I8X3|FGFR3_DANRE Fibroblast growth factor receptor 3 OS=Danio
rerio OX=7955 GN=fgfr3 PE=2 SV=1
Length=800
Score = 155 bits (391), Expect = 3e-37, Method: Compositional matrix adjust.
Identities = 115/364 (32%), Positives = 172/364 (47%), Gaps = 40/364 (11%)
Query 826 FYQRQHRLPEPSCPQLATL-TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884
+ Q LP P +L+ + ++ E + T L + RL + + V+
Sbjct 387 WINTQKTLPAPPVQKLSKFPLKRQVSLESNSSMNSNTPLVRIARLSSSDGPMLPNVSELE 446
Query 885 PASDPT-VFHKRYLKKIRDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQH 940
SDP F + L + LGEG FG+V + D VAVK LK D +
Sbjct 447 LPSDPKWEFTRTKLTLGKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKD 506
Query 941 RSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--------- 990
S E+++++ + H++II G C G L +++EY G+LR+YL
Sbjct 507 LSDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLYVLVEYASKGNLREYLRARRPPGMD 564
Query 991 --------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
P ++ L+ A Q+ GM YL ++ IHRD AARNVL+ D ++KI DF
Sbjct 565 YSFDTCKIPNETLTFKDLVSCAYQVARGMEYLASKKCIHRDPAARNVLVTEDNVMKIADF 624
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
GLA+ V +YY+ +G PV W APE L + + + SDVWS+GV L+E+ T
Sbjct 625 GLARDV-HNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFT------ 677
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
L G + V L +LL+ G R+ +P C E+Y +M+ CW S RPTF
Sbjct 678 --------LGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTF 729
Query 1163 ENLI 1166
L+
Sbjct 730 RQLV 733
Score = 64.3 bits (155), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 86/343 (25%), Positives = 146/343 (43%), Gaps = 54/343 (16%)
Query 558 TSNLIIMRGARAS----PRTLNLSQLSFHRVDQKEITQLS-HLGQGTRTNVYEGRLRVEG 612
SN ++R AR S P N+S+L + E T+ LG+ + + E
Sbjct 420 NSNTPLVRIARLSSSDGPMLPNVSELELPSDPKWEFTRTKLTLGKPLGEGCFGQVVMAEA 479
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHL 670
G +D E P P L V +K+L D + D++ E + H ++
Sbjct 480 IG------IDKEKPNKP-------LTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNI 526
Query 671 AFVHGVCVR-GPENIMVTEYVEHGPLDVWLRRER----------GHVP---MAWKMVV-- 714
+ G C + GP ++V EY G L +LR R +P + +K +V
Sbjct 527 INLLGACTQDGPLYVLV-EYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSC 585
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----RE 770
A Q+A + YL +K +H + RN+L+ + +K++D G+ + ++
Sbjct 586 AYQVARGMEYLASKKCIHRDPAARNVLVTEDNV-------MKIADFGLARDVHNIDYYKK 638
Query 771 ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
R+P W+APE L + + D W +G L EI G +P E +
Sbjct 639 TTNGRLPVKWMAPEALFDRVYTHQS--DVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLK 696
Query 829 RQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
HR+ +P+ C +L + +C P+QRP+FR ++ D R+
Sbjct 697 EGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDRV 739
>sp|P43404|ZAP70_MOUSE Tyrosine-protein kinase ZAP-70 OS=Mus musculus
OX=10090 GN=Zap70 PE=1 SV=3
Length=618
Score = 152 bits (385), Expect = 4e-37, Method: Compositional matrix adjust.
Identities = 123/377 (33%), Positives = 175/377 (46%), Gaps = 49/377 (13%)
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855
G L E+C + A +P+ H F Q Q R+ TL S T EP +
Sbjct 245 GLIYRLKEVCPNSSASAAVAAPTLPAHPSTFTQPQRRV--------DTLNSDGYTPEPAR 296
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP------TVFHKRYLKKIRD--LGEGH 907
S D R P + T +SP SDP +F KR + D LG G+
Sbjct 297 LASST----DKPRPMPMD-----TSVYESPYSDPEELKDKKLFLKRENLLVADIELGCGN 347
Query 908 FGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
FG V Y VA+K LK + +E I+ L + +I++ G C+
Sbjct 348 FGSVRQGVYRMRKKQID--VAIKVLKQGTEKADKDEMMREAQIMHQLDNPYIVRLIGVCQ 405
Query 968 DQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
+ +L LVME G L +L + I ++ + Q+ GM YL ++++HRDLA
Sbjct 406 AE---ALMLVMEMAGGGPLHKFLLGKKEEIPVSNVAELLHQVAMGMKYLEEKNFVHRDLA 462
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
ARNVLL N KI DFGL+KA+ YY R G P+ WYAPEC+ KF SDVW
Sbjct 463 ARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVW 522
Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
S+GVT++E ++ Q P K M + + +++G+R+ P +CP E+Y
Sbjct 523 SYGVTMWEAFSY---GQKPYKK-----------MKGPEVLDFIKQGKRMECPPECPPEMY 568
Query 1146 HLMKNCWETEASFRPTF 1162
LM +CW + RP F
Sbjct 569 ALMSDCWIYKWEDRPDF 585
Score = 86.7 bits (213), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 67/242 (28%), Positives = 110/242 (45%), Gaps = 20/242 (8%)
Query 631 RDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
R R +++ V +KVL A +M Q+ + ++ + GVC + ++V E
Sbjct 357 RMRKKQIDVAIKVLKQGTEKADKDEMMREAQIMHQLDNPYIVRLIGVC-QAEALMLVMEM 415
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
GPL +L ++ +P++ + Q+A + YLE KN VH ++ RN+LL
Sbjct 416 AGGGPLHKFLLGKKEEIPVSNVAELLHQVAMGMKYLEEKNFVHRDLAARNVLLV------ 469
Query 750 GTSPFIKLSDPGV--GLGA-----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+ K+SD G+ LGA +R + W APEC+ S+ D W +G
Sbjct 470 -NRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECI--NFRKFSSRSDVWSYGV 526
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP-EPSC-PQLATLTSQCLTYEPTQRPSFR 860
T+ E G+ P + E F ++ R+ P C P++ L S C Y+ RP F
Sbjct 527 TMWEAFSYGQKPYKKMKGPEVLDFIKQGKRMECPPECPPEMYALMSDCWIYKWEDRPDFL 586
Query 861 TI 862
T+
Sbjct 587 TV 588
>sp|G5EBZ8|ARK1_CAEEL Ack-related non-receptor tyrosine kinase
OS=Caenorhabditis elegans OX=6239 GN=ark-1 PE=2 SV=1
Length=1043
Score = 155 bits (391), Expect = 7e-37, Method: Compositional matrix adjust.
Identities = 94/272 (35%), Positives = 144/272 (53%), Gaps = 21/272 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
++LG+G FG V + + VAVK + +D S + QE I+ + HEH++
Sbjct 117 KELGQGEFGSVWQAGWKNSAGSDVIQVAVKCVGSDKLLATSSSFLQEAAIMTRMRHEHVV 176
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHA 1016
+ G D K + LV E GSL + L R S + L +A+QI GM+YL
Sbjct 177 RLYGVVLDT--KKIMLVSELATCGSLLECLHKPALRDSFPVHVLCDYAEQIAMGMSYLEL 234
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR--EDGDSPVFWYAPECLK 1074
Q IHRDLAARNVL+ + +LVKI DFGL++++ G +YYR + P+ W APEC+
Sbjct 235 QRLIHRDLAARNVLVFSPKLVKISDFGLSRSLGIGEDYYRSEFTPNLKLPIAWCAPECIN 294
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVW++GVT++E+ + + E+ + +L L + + E L
Sbjct 295 FLKFTSKSDVWAYGVTIWEMFS-----------YGEMPWKGRSGAQILELVD--RKKELL 341
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
RP CP ++Y ++K W + RPTF +++
Sbjct 342 TRPKACPEDIYDMLKETWTHQVQDRPTFSDIV 373
Score = 75.9 bits (185), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 60/225 (27%), Positives = 110/225 (49%), Gaps = 25/225 (11%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE--RGHVPMAWK 711
+F + A++M+++ H H+ ++GV + + ++V+E G L L + R P+
Sbjct 159 SFLQEAAIMTRMRHEHVVRLYGVVLDTKKIMLVSELATCGSLLECLHKPALRDSFPVHVL 218
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV--GLGALSR 769
A+Q+A +SYLE + L+H ++ RN+L+ + +K+SD G+ LG
Sbjct 219 CDYAEQIAMGMSYLELQRLIHRDLAARNVLVF-------SPKLVKISDFGLSRSLGIGED 271
Query 770 EERVERIP-------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
R E P W APEC+ ++ D W +G T+ E+ GE P + RS ++
Sbjct 272 YYRSEFTPNLKLPIAWCAPECI--NFLKFTSKSDVWAYGVTIWEMFSYGEMPWKGRSGAQ 329
Query 823 KEHFYQRQHRL---PEPSCPQ-LATLTSQCLTYEPTQRPSFRTIL 863
R+ L P+ +CP+ + + + T++ RP+F I+
Sbjct 330 ILELVDRKKELLTRPK-ACPEDIYDMLKETWTHQVQDRPTFSDIV 373
>sp|Q86PM4|FGFR_HYDVU Fibroblast growth factor receptor OS=Hydra
vulgaris OX=6087 GN=FGFR PE=2 SV=1
Length=816
Score = 154 bits (388), Expect = 8e-37, Method: Compositional matrix adjust.
Identities = 104/282 (37%), Positives = 148/282 (52%), Gaps = 31/282 (11%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHII 960
LGEG FG+V D N + VAVK LK DC Q + EI++++++ H +I+
Sbjct 480 LGEGAFGRVFRATARDLPNHTGVQTVAVKMLKEDCCEQDLKDFISEIEVMKSIGKHINIL 539
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------------SIGLAQLLLFAQQIC 1008
QG+ L +V+EY G+LR +L + I L L F Q+
Sbjct 540 NLLAVSSQQGK--LYIVVEYCRHGNLRSFLKDNRPVMQANSVITKKITLYDLTSFCLQVA 597
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
GM +L ++ IHRD+AARNVL+ L+KI DFGLA+ + E +YYR DG PV W
Sbjct 598 RGMNFLASKKCIHRDIAARNVLVGEGYLMKIADFGLARDIHE-QDYYRKCTDGRLPVKWM 656
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A E L + + SD+WSFG+ +E++T S GIA + +L +LL
Sbjct 657 AIEALFDRVYTTQSDIWSFGILAWEIVTFGGSPYP---------GIA-----LEKLFDLL 702
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
++G R+ RP C ++Y LM NCW+ S RPTF LI L+
Sbjct 703 KQGYRMERPLNCTDDMYTLMLNCWKEIPSKRPTFSQLIEDLE 744
Score = 58.5 bits (140), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 64/290 (22%), Positives = 116/290 (40%), Gaps = 35/290 (12%)
Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
+P Q + V + D D+ E + S H ++ + V + + +V
Sbjct 496 LPNHTGVQTVAVKMLKEDCCEQDLKDFISEIEVMKSIGKHINILNLLAVSSQQGKLYIVV 555
Query 688 EYVEHGPLDVWLRRER----GHVPMAWKMVVAQ------QLASALSYLENKNLVHGNVCG 737
EY HG L +L+ R + + K+ + Q+A +++L +K +H ++
Sbjct 556 EYCRHGNLRSFLKDNRPVMQANSVITKKITLYDLTSFCLQVARGMNFLASKKCIHRDIAA 615
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER--------IPWLAPECLPGGAN 789
RN+L+ G +K++D GL E+ R + W+A E L
Sbjct 616 RNVLV-------GEGYLMKIAD--FGLARDIHEQDYYRKCTDGRLPVKWMAIEALFDRV- 665
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQ 847
+T D W FG EI G +P + + ++ +R+ P +C + TL
Sbjct 666 -YTTQSDIWSFGILAWEIVTFGGSPYPGIALEKLFDLLKQGYRMERPLNCTDDMYTLMLN 724
Query 848 CLTYEPTQRPSFRTILRDLTRL----QPHNLADVLTVNPDSPASDPTVFH 893
C P++RP+F ++ DL R+ D+ + P+ S T H
Sbjct 725 CWKEIPSKRPTFSQLIEDLERMLLDASSTEYIDLQPIQPERTESFSTSLH 774
>sp|P42686|SRK1_SPOLA Tyrosine-protein kinase isoform SRK1 OS=Spongilla
lacustris OX=6055 GN=SRK1 PE=2 SV=1
Length=505
Score = 149 bits (377), Expect = 9e-37, Method: Compositional matrix adjust.
Identities = 98/282 (35%), Positives = 144/282 (51%), Gaps = 27/282 (10%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
A++ K +K +R LG G FG+V ++ T VAVK LK G +
Sbjct 229 ANEEWEIEKTQIKLLRRLGAGQFGEVWEGLWNGTTS-----VAVKTLKP--GTMSVEEFL 281
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLF 1003
QE I++ L H +I+ C E+ + +V E + GSL +YL + + QL+
Sbjct 282 QEASIMKRLRHPKLIQLYAVCTK--EEPIYIVTELMKYGSLLEYLRGEDGVLKIEQLVDV 339
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
A Q+ GM+YL Q+YIHRDLAARN+L+ + K+ DFGLA+ + E E Y
Sbjct 340 AAQVASGMSYLEQQNYIHRDLAARNILVGEHGICKVADFGLARVIDE--EIYEAHTGAKF 397
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
P+ W APE +F SDVWSFGV LYE++T+ + P MT
Sbjct 398 PIKWTAPEAAMYNRFTIKSDVWSFGVVLYEIITY---GRFPYPG-----------MTNPE 443
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ E +++ R+P P CP + + +M +CW + + RPTFE L
Sbjct 444 VLEKIQQNYRMPCPANCPKQFHDIMLDCWREDPASRPTFETL 485
Score = 102 bits (254), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 73/233 (31%), Positives = 111/233 (48%), Gaps = 21/233 (9%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K L P + F + AS+M ++ H L ++ VC + +VTE +++G L +
Sbjct 265 VAVKTLKPGTMSVE-EFLQEASIMKRLRHPKLIQLYAVCTKEEPIYIVTELMKYGSLLEY 323
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
LR E G + + + VA Q+AS +SYLE +N +H ++ RNIL+ G+ K++
Sbjct 324 LRGEDGVLKIEQLVDVAAQVASGMSYLEQQNYIHRDLAARNILVGEHGIC-------KVA 376
Query 759 DPGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
D GL + EE E I W APE N + D W FG L EI G
Sbjct 377 D--FGLARVIDEEIYEAHTGAKFPIKWTAPEA--AMYNRFTIKSDVWSFGVVLYEIITYG 432
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862
P + E Q+ +R+P P+ CP Q + C +P RP+F T+
Sbjct 433 RFPYPGMTNPEVLEKIQQNYRMPCPANCPKQFHDIMLDCWREDPASRPTFETL 485
>sp|P0CY46|EGFR_APIME Epidermal growth factor receptor OS=Apis
mellifera OX=7460 GN=Egfr PE=2 SV=1
Length=1292
Score = 155 bits (391), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 97/277 (35%), Positives = 141/277 (51%), Gaps = 20/277 (7%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+ + ++K LG G FG V + P + VA+K L G + E I
Sbjct 705 IIKEEEMRKGGILGYGAFGNVYKGVWVPEGENVKIPVAIKVLHDGTGANTSKEFLDEAYI 764
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQIC 1008
+ ++ H ++++ C + LV + +PLG L D++ R IG LL + QI
Sbjct 765 MASVEHPNLLQLLAVCM---TSQMMLVTQLMPLGCLLDFVRRFKDKIGSKALLNWCTQIA 821
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
GMAYL + +HRDLAARNVL+ VKI DFGLAK + E Y+ G P+ W
Sbjct 822 RGMAYLEERRLVHRDLAARNVLVQTPNCVKITDFGLAKLLDINEEQYKA-AGGKMPIKWL 880
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A EC++ F + SDVW+FGVT++E+LT+ G + + ELL
Sbjct 881 ALECIQHRVFTHKSDVWAFGVTIWEVLTY--------------GGRPYENVPARNVPELL 926
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
E+GERLP+P C +VY +M CW +A RP+F+ L
Sbjct 927 EKGERLPQPAICTIDVYMIMIKCWMLDAESRPSFKEL 963
Score = 84.0 bits (206), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 83/348 (24%), Positives = 152/348 (44%), Gaps = 42/348 (12%)
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
NL++L + ++E+ + LG G NVY+G EG E+ +P
Sbjct 699 NLAKLRI--IKEEEMRKGGILGYGAFGNVYKGVWVPEG-----------ENVKIP----- 740
Query 635 QELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
V +KVL D + + + F + A +M+ V H +L + VC+ + ++VT+ + G
Sbjct 741 ----VAIKVLHDGTGANTSKEFLDEAYIMASVEHPNLLQLLAVCMTS-QMMLVTQLMPLG 795
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L ++RR + + + Q+A ++YLE + LVH ++ RN+L+ T
Sbjct 796 CLLDFVRRFKDKIGSKALLNWCTQIARGMAYLEERRLVHRDLAARNVLVQ-------TPN 848
Query 754 FIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K++D G+ EE+ + I WLA EC+ + D W FG T+ E+
Sbjct 849 CVKITDFGLAKLLDINEEQYKAAGGKMPIKWLALECI--QHRVFTHKSDVWAFGVTIWEV 906
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRD 865
G P ++ ++ RLP+P+ + + +C + RPSF+ + D
Sbjct 907 LTYGGRPYENVPARNVPELLEKGERLPQPAICTIDVYMIMIKCWMLDAESRPSFKELAED 966
Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
++ + L + D P+ + + IR+L G +L
Sbjct 967 FAKMS-RDPGRYLAIKGDKYMRLPSYTLQDEKEMIRNLASAMDGPEAL 1013
>sp|P17713|STK_HYDVU Tyrosine-protein kinase STK OS=Hydra vulgaris
OX=6087 GN=STK PE=2 SV=1
Length=509
Score = 149 bits (376), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 95/288 (33%), Positives = 146/288 (51%), Gaps = 28/288 (10%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
A D + L+ R LG G FG+V ++ T VAVK LK G + +
Sbjct 229 AKDAWEIPRESLRLNRKLGAGQFGEVWAGVWNNTT-----QVAVKTLKP--GTMSPASFL 281
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLL 1002
E +++ L H+H+++ C D+ + + +V EY+ GSL DYL + ++ L L+
Sbjct 282 DEAGVMKKLRHKHLVQLYAICSDR--EPIYIVTEYMSGGSLLDYLSKGEGVNLQLPTLID 339
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
A Q+ GMA+L AQ YIHRDLAARN+L+ + + K+ DFGLA+ + + + Y E
Sbjct 340 MAAQVASGMAFLEAQGYIHRDLAARNILVGENYICKVADFGLARLIED--DEYTAHEGAK 397
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
P+ W APE +F SDVWSFG+ + E++T I MT
Sbjct 398 FPIKWTAPEAALYNRFTIKSDVWSFGILMAEIVTKGR--------------IPYPGMTNA 443
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ +E+G R+P CP +Y++M W + RPTF+ L +L+
Sbjct 444 QTIAEVEKGYRMPIMPGCPEPLYNIMLQTWNKDPENRPTFDYLQGVLE 491
Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 62/232 (27%), Positives = 108/232 (47%), Gaps = 22/232 (9%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P A +F + A +M ++ H HL ++ +C +VTEY+ G L
Sbjct 264 QVAVKTLKPGTMSPA-SFLDEAGVMKKLRHKHLVQLYAICSDREPIYIVTEYMSGGSLLD 322
Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L + G ++ + + +A Q+AS +++LE + +H ++ RNIL+ G + K
Sbjct 323 YLSKGEGVNLQLPTLIDMAAQVASGMAFLEAQGYIHRDLAARNILV-------GENYICK 375
Query 757 LSDPGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
++D GL L ++ I W APE N + D W FG + EI
Sbjct 376 VAD--FGLARLIEDDEYTAHEGAKFPIKWTAPEA--ALYNRFTIKSDVWSFGILMAEIVT 431
Query 810 DGEAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859
G P + ++ ++ +R+P P CP+ L + Q +P RP+F
Sbjct 432 KGRIPYPGMTNAQTIAEVEKGYRMPIMPGCPEPLYNIMLQTWNKDPENRPTF 483
>sp|Q9H3Y6|SRMS_HUMAN Tyrosine-protein kinase Srms OS=Homo sapiens
OX=9606 GN=SRMS PE=1 SV=1
Length=488
Score = 148 bits (374), Expect = 2e-36, Method: Compositional matrix adjust.
Identities = 102/277 (37%), Positives = 142/277 (51%), Gaps = 30/277 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
R LGEG+FG+V + G + VA+K +K+ + +EI L+ L HE +
Sbjct 234 RKLGEGYFGEVWEGLW------LGSLPVAIKVIKS--ANMKLTDLAKEIQTLKGLRHERL 285
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHA 1016
I+ C G + + +V E + G+L+ +L ++ L LL FA Q+ EGM+YL
Sbjct 286 IRLHAVC--SGGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLGFACQVAEGMSYLEE 343
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
Q +HRDLAARNVL+D+ K+ DFGLA+ + + + Y PV W APE
Sbjct 344 QRVVHRDLAARNVLVDDGLACKVADFGLARLLKD--DIYSPSSSSKIPVKWTAPEAANYR 401
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
F SDVWSFGV L+E+ T+ Q P +G MT + + RG RLPR
Sbjct 402 VFSQKSDVWSFGVLLHEVFTY---GQCP----------YEG-MTNHETLQQIMRGYRLPR 447
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
P CP EVY LM CW + RP+F L L +H
Sbjct 448 PAACPAEVYVLMLECWRSSPEERPSFATLREKLHAIH 484
Score = 79.3 bits (194), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 71/240 (30%), Positives = 110/240 (46%), Gaps = 22/240 (9%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
L V +KV+ ++ + E +L + H L +H VC G +VTE + G L
Sbjct 253 LPVAIKVIKSANMKLTDLAKEIQTLKG-LRHERLIRLHAVCSGGEPVYIVTELMRKGNLQ 311
Query 697 VWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+L G + + + A Q+A +SYLE + +VH ++ RN+L+ GLA
Sbjct 312 AFLGTPEGRALRLPPLLGFACQVAEGMSYLEEQRVVHRDLAARNVLVDD-GLA------C 364
Query 756 KLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
K++D GL L +++ +IP W APE S D W FG L E+
Sbjct 365 KVAD--FGLARLLKDDIYSPSSSSKIPVKWTAPEA--ANYRVFSQKSDVWSFGVLLHEVF 420
Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDL 866
G+ P + + E R +RLP P +CP ++ L +C P +RPSF T+ L
Sbjct 421 TYGQCPYEGMTNHETLQQIMRGYRLPRPAACPAEVYVLMLECWRSSPEERPSFATLREKL 480
>sp|Q91743|FGFR4_XENLA Fibroblast growth factor receptor 4 OS=Xenopus
laevis OX=8355 GN=fgfr4 PE=2 SV=1
Length=828
Score = 152 bits (383), Expect = 3e-36, Method: Compositional matrix adjust.
Identities = 103/300 (34%), Positives = 151/300 (50%), Gaps = 41/300 (14%)
Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956
+ LGEG FG+V Y + VAVK LK + + S E+++++ + H
Sbjct 494 KPLGEGCFGQVVRAEGYGIEKDRPEKPVTVAVKMLKDNGTDKDLSDLISEMELMKVIGKH 553
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999
++II G C +G L +++EY G+LR++L P +
Sbjct 554 KNIINLLGVCTQEG--PLFVIVEYASKGNLREFLRARRPPTPEDAFDITKVPEELLSFKD 611
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ V + +YY+
Sbjct 612 LVSCAYQVARGMEYLESKRCIHRDLAARNVLVAEDNVMKIADFGLARGVHD-IDYYKKTS 670
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
+G PV W APE L + + + SD+WSFGV +E+ T S P + EL
Sbjct 671 NGRLPVKWMAPEALFDRVYTHQSDIWSFGVLTWEIFT-LGGSPYPVIPYEELF------- 722
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF---ENLIPILKTVHEKY 1176
+LL G R+ +P C E+Y LM+ CW + RPTF E+L IL V E+Y
Sbjct 723 ------KLLREGHRMDKPSNCTHELYMLMRECWHAVPTQRPTFKQLEHLDRILTAVSEEY 776
Score = 70.5 bits (171), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 69/258 (27%), Positives = 117/258 (45%), Gaps = 35/258 (14%)
Query 631 RDRGQE-LRVVLKVLDPSHHDIALA-FYETASLMSQV-SHTHLAFVHGVCVRGPENIMVT 687
+DR ++ + V +K+L + D L+ LM + H ++ + GVC + ++
Sbjct 514 KDRPEKPVTVAVKMLKDNGTDKDLSDLISEMELMKVIGKHKNIINLLGVCTQEGPLFVIV 573
Query 688 EYVEHGPLDVWLRRERGHVP-------------MAWKMVV--AQQLASALSYLENKNLVH 732
EY G L +LR R P +++K +V A Q+A + YLE+K +H
Sbjct 574 EYASKGNLREFLRARRPPTPEDAFDITKVPEELLSFKDLVSCAYQVARGMEYLESKRCIH 633
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPG 786
++ RN+L+A + +K++D G+ G ++ R+P W+APE L
Sbjct 634 RDLAARNVLVAEDNV-------MKIADFGLARGVHDIDYYKKTSNGRLPVKWMAPEALFD 686
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATL 844
+ + D W FG EI G +P E + HR+ +PS C +L L
Sbjct 687 RVYTHQS--DIWSFGVLTWEIFTLGGSPYPVIPYEELFKLLREGHRMDKPSNCTHELYML 744
Query 845 TSQCLTYEPTQRPSFRTI 862
+C PTQRP+F+ +
Sbjct 745 MRECWHAVPTQRPTFKQL 762
>sp|Q62371|DDR2_MOUSE Discoidin domain-containing receptor 2 OS=Mus
musculus OX=10090 GN=Ddr2 PE=1 SV=2
Length=854
Score = 152 bits (383), Expect = 3e-36, Method: Compositional matrix adjust.
Identities = 99/299 (33%), Positives = 148/299 (49%), Gaps = 37/299 (12%)
Query 892 FHKRYLKKIRDLGEGHFGKVSL-------------YCYDPTNDGTGEMVAVKALKADCGP 938
F ++ L LGEG FG+V L + D + + +VAVK L+AD
Sbjct 558 FPRKLLAFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN-QPVLVAVKMLRADANK 616
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----- 993
R+ + +EI I+ L +II+ C E L ++ EY+ G L +L RH
Sbjct 617 NARNDFLKEIKIMSRLKDPNIIRLLAVC--ITEDPLCMITEYMENGDLNQFLSRHEPLSS 674
Query 994 -----SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
++ A L A QI GM YL + +++HRDLA RN L+ + +KI DFG+++ +
Sbjct 675 CSSDATVSYANLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNL 734
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
G +YYR++ P+ W + E + KF ASDVW+FGVTL+E T C Q P
Sbjct 735 YSG-DYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC---QEQPYSQ 790
Query 1109 LELIGIAQGQMTVLRLTELLERGER--LPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L + + R ++G + LP+P CP VY LM +CW E RP+F+ +
Sbjct 791 LSDEQVIENTGEFFR-----DQGRQIYLPQPALCPDSVYKLMLSCWRRETKHRPSFQEI 844
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 73/254 (29%), Positives = 113/254 (44%), Gaps = 34/254 (13%)
Query 634 GQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
Q + V +K+L + A F + +MS++ ++ + VC+ M+TEY+E+
Sbjct 600 NQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIRLLAVCITEDPLCMITEYMEN 659
Query 693 GPLDVWLRRER--------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
G L+ +L R V A +A Q+AS + YL + N VH ++ RN L+
Sbjct 660 GDLNQFLSRHEPLSSCSSDATVSYANLKFMATQIASGMKYLSSLNFVHRDLATRNCLV-- 717
Query 745 LGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKW 798
G + IK++D G+ S + V I W++ E + G +TA D W
Sbjct 718 -----GKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLG--KFTTASDVW 770
Query 799 GFGATLLE-ICFDGEAPLQSRSPSE----KEHFYQRQHR---LPEPS-CPQ-LATLTSQC 848
FG TL E F E P S + F++ Q R LP+P+ CP + L C
Sbjct 771 AFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQIYLPQPALCPDSVYKLMLSC 830
Query 849 LTYEPTQRPSFRTI 862
E RPSF+ I
Sbjct 831 WRRETKHRPSFQEI 844
>sp|Q62190|RON_MOUSE Macrophage-stimulating protein receptor OS=Mus
musculus OX=10090 GN=Mst1r PE=1 SV=3
Length=1378
Score = 153 bits (386), Expect = 4e-36, Method: Compositional matrix adjust.
Identities = 112/327 (34%), Positives = 168/327 (51%), Gaps = 37/327 (11%)
Query 854 TQRPSFRT---ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910
T P RT L+DL R+ + DVL + + V H + +G+GHFG
Sbjct 1024 TSVPLLRTESIRLQDLDRMLLAEVKDVLIPH------EQVVIHTDQV-----IGKGHFGV 1072
Query 911 VSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
V Y + T+ + A+K+L Q + +E ++R L+H +I+ G
Sbjct 1073 V--YHGEYTDGAQNQTHCAIKSLSRITEVQEVEAFLREGLLMRGLHHPNILALIGIMLPP 1130
Query 970 GEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027
E ++++ Y+ G L ++ P+ + + L+ F Q+ GM YL Q ++HRDLAAR
Sbjct 1131 -EGLPRVLLPYMRHGDLLHFIRSPQRNPTVKDLVSFGLQVACGMEYLAEQKFVHRDLAAR 1189
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS--PVFWYAPECLKEYKFYYASDVW 1085
N +LD VK+ DFGLA+ V + EYY VR+ + PV W A E L+ Y+F SDVW
Sbjct 1190 NCMLDESFTVKVADFGLARGVLD-KEYYSVRQHRHARLPVKWMALESLQTYRFTTKSDVW 1248
Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
SFGV L+ELLT +PP ++ L+ L +G RLP+P+ CP +Y
Sbjct 1249 SFGVLLWELLTR----GAPPYPHID----------PFDLSHFLAQGRRLPQPEYCPDSLY 1294
Query 1146 HLMKNCWETEASFRPTFENLIPILKTV 1172
H+M CWE + + RPTF L+ +K V
Sbjct 1295 HVMLRCWEADPAARPTFRALVLEVKQV 1321
Score = 75.1 bits (183), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 63/235 (27%), Positives = 107/235 (46%), Gaps = 22/235 (9%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENI--MVTEYVEHGPLDVWLRRERGHVPMAWK 711
AF LM + H ++ + G+ + PE + ++ Y+ HG L ++R + + +
Sbjct 1104 AFLREGLLMRGLHHPNILALIGIMLP-PEGLPRVLLPYMRHGDLLHFIRSPQRNPTVKDL 1162
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--- 768
+ Q+A + YL + VH ++ RN +L S +K++D G+ G L
Sbjct 1163 VSFGLQVACGMEYLAEQKFVHRDLAARNCMLDE-------SFTVKVADFGLARGVLDKEY 1215
Query 769 ---REERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
R+ R R+P W+A E L +T D W FG L E+ G P P +
Sbjct 1216 YSVRQHRHARLPVKWMALESL--QTYRFTTKSDVWSFGVLLWELLTRGAPPYPHIDPFDL 1273
Query 824 EHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
HF + RLP+P CP L + +C +P RP+FR ++ ++ ++ L D
Sbjct 1274 SHFLAQGRRLPQPEYCPDSLYHVMLRCWEADPAARPTFRALVLEVKQVVASLLGD 1328
>sp|Q62270|SRMS_MOUSE Tyrosine-protein kinase Srms OS=Mus musculus
OX=10090 GN=Srms PE=2 SV=2
Length=496
Score = 147 bits (370), Expect = 6e-36, Method: Compositional matrix adjust.
Identities = 104/278 (37%), Positives = 145/278 (52%), Gaps = 28/278 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LGEG FG+V ++ G+ VAVK +K+ + +EI+ L++L HE +I
Sbjct 238 RKLGEGFFGEV----WEGLWLGSIP-VAVKVIKS--ADMKLADLTKEIEALKSLRHERLI 290
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ C GE + +V E + G+L+ YL ++ L LL FA Q+ EGM+YL +
Sbjct 291 RLHAIC-SLGE-PVYIVTELMGKGNLQVYLGSSEGKALSLPHLLGFACQVAEGMSYLEER 348
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDLAARNVL+ +D K+ DFGLA+ + + + Y PV W APE
Sbjct 349 RVVHRDLAARNVLVGDDLTCKVADFGLARLLKD--DVYSPSSGSKIPVKWTAPEAANYRV 406
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFG+ LYE+ T+ Q P +G MT + + RG RLPRP
Sbjct 407 FSQKSDVWSFGILLYEVFTY---GQCP----------YEG-MTNHETLQQISRGYRLPRP 452
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
CP EVY LM CW+ RPTF L L ++ +
Sbjct 453 AVCPAEVYVLMVECWKGSPEERPTFAILREKLNAINRR 490
Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 70/237 (30%), Positives = 110/237 (46%), Gaps = 23/237 (10%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +KV+ + +A E +L S + H L +H +C G +VTE + G L V+
Sbjct 259 VAVKVIKSADMKLADLTKEIEALKS-LRHERLIRLHAICSLGEPVYIVTELMGKGNLQVY 317
Query 699 LRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
L G + + + A Q+A +SYLE + +VH ++ RN+L+ G K+
Sbjct 318 LGSSEGKALSLPHLLGFACQVAEGMSYLEERRVVHRDLAARNVLV-------GDDLTCKV 370
Query 758 SDPGVGLGALSREERVE-----RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+D GL L +++ +IP W APE S D W FG L E+
Sbjct 371 AD--FGLARLLKDDVYSPSSGSKIPVKWTAPEA--ANYRVFSQKSDVWSFGILLYEVFTY 426
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRD 865
G+ P + + E R +RLP P+ CP ++ L +C P +RP+F ILR+
Sbjct 427 GQCPYEGMTNHETLQQISRGYRLPRPAVCPAEVYVLMVECWKGSPEERPTF-AILRE 482
>sp|Q03145|EPHA2_MOUSE Ephrin type-A receptor 2 OS=Mus musculus
OX=10090 GN=Epha2 PE=1 SV=3
Length=977
Score = 151 bits (382), Expect = 7e-36, Method: Compositional matrix adjust.
Identities = 87/282 (31%), Positives = 143/282 (51%), Gaps = 18/282 (6%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
T H + + + +G G FG+V ++ VA+K LKA + R + E
Sbjct 607 TEIHPSCVARQKVIGAGEFGEVYKGTLKASSGKKEIPVAIKTLKAGYTEKQRVDFLSEAS 666
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQI 1007
I+ H +II+ +G K + ++ EY+ G+L +L + QL+ + I
Sbjct 667 IMGQFSHHNIIRLEGVVSKY--KPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGI 724
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
GM YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W
Sbjct 725 ASGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRW 784
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + KF ASDVWS+G+ ++E++T+ + + EL + + +
Sbjct 785 TAPEAISYRKFTSASDVWSYGIVMWEVMTYGER------PYWEL--------SNHEVMKA 830
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ G RLP P CP +Y LM CW+ E S RP F +++ IL
Sbjct 831 INDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVSIL 872
Score = 95.9 bits (237), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 75/260 (29%), Positives = 121/260 (47%), Gaps = 21/260 (8%)
Query 635 QELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+E+ V +K L + + + F AS+M Q SH ++ + GV + +++TEY+E+G
Sbjct 640 KEIPVAIKTLKAGYTEKQRVDFLSEASIMGQFSHHNIIRLEGVVSKYKPMMIITEYMENG 699
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
LD +LR + G + + + + +AS + YL N N VH ++ RNIL+ ++
Sbjct 700 ALDKFLREKDGEFSVLQLVGMLRGIASGMKYLANMNYVHRDLAARNILV-------NSNL 752
Query 754 FIKLSDPGVGLGALSREERVE-----RIP--WLAPECLPGGANSLSTAMDKWGFGATLLE 806
K+SD G+ E +IP W APE + ++A D W +G + E
Sbjct 753 VCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAI--SYRKFTSASDVWSYGIVMWE 810
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILR 864
+ GE P S E RLP P CP + L QC E ++RP F I+
Sbjct 811 VMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVS 870
Query 865 DLTRL--QPHNLADVLTVNP 882
L +L P +L + +P
Sbjct 871 ILDKLIRAPDSLKTLADFDP 890
>sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens
OX=9606 GN=EPHA2 PE=1 SV=2
Length=976
Score = 151 bits (381), Expect = 8e-36, Method: Compositional matrix adjust.
Identities = 90/283 (32%), Positives = 146/283 (52%), Gaps = 20/283 (7%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEI 948
T H + + + +G G FG+V T+ G E+ VA+K LKA + R + E
Sbjct 606 TEIHPSCVTRQKVIGAGEFGEVYKGMLK-TSSGKKEVPVAIKTLKAGYTEKQRVDFLGEA 664
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006
I+ H +II+ +G K + ++ EY+ G+L +L + QL+ +
Sbjct 665 GIMGQFSHHNIIRLEGVISKY--KPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRG 722
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+
Sbjct 723 IAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIR 782
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE + KF ASDVWSFG+ ++E++T+ + + EL + + +
Sbjct 783 WTAPEAISYRKFTSASDVWSFGIVMWEVMTYGER------PYWEL--------SNHEVMK 828
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ G RLP P CP +Y LM CW+ E + RP F +++ IL
Sbjct 829 AINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSIL 871
Score = 93.6 bits (231), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 83/306 (27%), Positives = 133/306 (43%), Gaps = 41/306 (13%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+T+ +G G VY+G L+ GK +E+ V +K L +
Sbjct 613 VTRQKVIGAGEFGEVYKGMLKTSS------GK--------------KEVPVAIKTLKAGY 652
Query 649 HDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
+ + F A +M Q SH ++ + GV + +++TEY+E+G LD +LR + G
Sbjct 653 TEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFS 712
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
+ + + + +A+ + YL N N VH ++ RNIL+ ++ K+SD G+
Sbjct 713 VLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILV-------NSNLVCKVSDFGLSRVLE 765
Query 768 SREERVE-----RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
E +IP W APE + ++A D W FG + E+ GE P S
Sbjct 766 DDPEATYTTSGGKIPIRWTAPEAI--SYRKFTSASDVWSFGIVMWEVMTYGERPYWELSN 823
Query 821 SEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLAD 876
E RLP P CP + L QC E +RP F I+ L +L P +L
Sbjct 824 HEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKT 883
Query 877 VLTVNP 882
+ +P
Sbjct 884 LADFDP 889
>sp|P35546|RET_MOUSE Proto-oncogene tyrosine-protein kinase receptor
Ret OS=Mus musculus OX=10090 GN=Ret PE=1 SV=2
Length=1115
Score = 151 bits (382), Expect = 9e-36, Method: Compositional matrix adjust.
Identities = 104/310 (34%), Positives = 143/310 (46%), Gaps = 43/310 (14%)
Query 892 FHKRYLKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
F ++ L + LGEG FGKV + VAVK LK + E ++
Sbjct 720 FPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNL 779
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------------------- 990
L+ + H H+IK G C G L L++EY GSLR +L
Sbjct 780 LKQVNHPHVIKLYGACSQDG--PLLLIVEYAKYGSLRGFLRDSRKIGPAYVSGGGSRNSS 837
Query 991 -----PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+ + L+ FA QI GM YL +HRDLAARN+L+ R +KI DFGL+
Sbjct 838 SLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLS 897
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ V E Y + + G PV W A E L ++ + SDVWSFGV L+E++T
Sbjct 898 RDVYEEDSYVK-KSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVT--------- 947
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L G + RL LL+ G R+ RPD C E+Y LM CW+ E RP F ++
Sbjct 948 -----LGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 1002
Query 1166 IPILKTVHEK 1175
L+ + K
Sbjct 1003 SKDLEKMMVK 1012
Score = 79.3 bits (194), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 67/241 (28%), Positives = 105/241 (44%), Gaps = 40/241 (17%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------------ 707
+L+ QV+H H+ ++G C + +++ EY ++G L +LR R P
Sbjct 778 NLLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIGPAYVSGGGSRNSS 837
Query 708 -----------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
M + A Q++ + YL LVH ++ RNIL +AEG +K
Sbjct 838 SLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNIL-----VAEGRK--MK 890
Query 757 LSDPGVGLGALSREERVE----RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+SD G+ + V+ RIP W+A E L + +T D W FG L EI
Sbjct 891 ISDFGLSRDVYEEDSYVKKSKGRIPVKWMAIESL--FDHIYTTQSDVWSFGVLLWEIVTL 948
Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
G P P + + HR+ P+ ++ L QC EP +RP F I +DL +
Sbjct 949 GGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEK 1008
Query 869 L 869
+
Sbjct 1009 M 1009
>sp|G3V9H8|RET_RAT Proto-oncogene tyrosine-protein kinase receptor
Ret OS=Rattus norvegicus OX=10116 GN=Ret PE=1 SV=1
Length=1115
Score = 151 bits (382), Expect = 9e-36, Method: Compositional matrix adjust.
Identities = 104/310 (34%), Positives = 143/310 (46%), Gaps = 43/310 (14%)
Query 892 FHKRYLKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
F ++ L + LGEG FGKV + VAVK LK + E ++
Sbjct 720 FPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNL 779
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------------------- 990
L+ + H H+IK G C G L L++EY GSLR +L
Sbjct 780 LKQVNHPHVIKLYGACSQDG--PLLLIVEYAKYGSLRGFLRDSRKIGPAYVSSGGSRNSS 837
Query 991 -----PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+ + L+ FA QI GM YL +HRDLAARN+L+ R +KI DFGL+
Sbjct 838 SLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLS 897
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ V E Y + + G PV W A E L ++ + SDVWSFGV L+E++T
Sbjct 898 RDVYEEDSYVK-KSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVT--------- 947
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L G + RL LL+ G R+ RPD C E+Y LM CW+ E RP F ++
Sbjct 948 -----LGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 1002
Query 1166 IPILKTVHEK 1175
L+ + K
Sbjct 1003 SKDLEKMMVK 1012
Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 67/241 (28%), Positives = 105/241 (44%), Gaps = 40/241 (17%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------------ 707
+L+ QV+H H+ ++G C + +++ EY ++G L +LR R P
Sbjct 778 NLLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIGPAYVSSGGSRNSS 837
Query 708 -----------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
M + A Q++ + YL LVH ++ RNIL +AEG +K
Sbjct 838 SLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNIL-----VAEGRK--MK 890
Query 757 LSDPGVGLGALSREERVE----RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+SD G+ + V+ RIP W+A E L + +T D W FG L EI
Sbjct 891 ISDFGLSRDVYEEDSYVKKSKGRIPVKWMAIESL--FDHIYTTQSDVWSFGVLLWEIVTL 948
Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
G P P + + HR+ P+ ++ L QC EP +RP F I +DL +
Sbjct 949 GGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEK 1008
Query 869 L 869
+
Sbjct 1009 M 1009
>sp|P13406|FYN_XENLA Tyrosine-protein kinase Fyn OS=Xenopus laevis
OX=8355 GN=fyn PE=2 SV=3
Length=537
Score = 147 bits (370), Expect = 1e-35, Method: Compositional matrix adjust.
Identities = 92/277 (33%), Positives = 139/277 (50%), Gaps = 29/277 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ I+ LG G FG+V + ++ VA+K LK G + +E I++ L H
Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAIKTLKP--GTMSPESFLEEAQIMKKLKH 323
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013
+ +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY
Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVARGMAY 380
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ +YIHRDL + N+L+ N + KI DFGLA+ + + Y R+ P+ W APE
Sbjct 381 IERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+F SDVWSFG+ L EL+T + M + E +ERG R
Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+P P CP ++ LM NCW+ + RPTFE L L+
Sbjct 485 MPCPQDCPISLHELMLNCWKKDPEERPTFEYLQGFLE 521
Score = 76.6 bits (187), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 65/230 (28%), Positives = 101/230 (44%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L
Sbjct 295 KVAIKTLKPGTMSPE-SFLEEAQIMKKLKHDKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 352
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G +V +A Q+A ++Y+E N +H ++ NIL+ G K
Sbjct 353 FLKDGEGRALKLPNLVDMAAQVARGMAYIERMNYIHRDLRSANILV-------GNGLICK 405
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
P + E +R +R+P P CP L L C +P +RP+F
Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMLNCWKKDPEERPTF 513
>sp|P00527|YES_AVISY Tyrosine-protein kinase transforming protein
Yes (Fragment) OS=Y73 avian sarcoma virus OX=11884 GN=V-YES
PE=3 SV=2
Length=528
Score = 146 bits (369), Expect = 1e-35, Method: Compositional matrix adjust.
Identities = 101/305 (33%), Positives = 150/305 (49%), Gaps = 32/305 (10%)
Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
H L V TV P + A D + L+ LG+G FG+V + ++ T VA
Sbjct 239 HKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK-----VA 293
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL D
Sbjct 294 IKTLK--LGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVS---EEPIYIVTEFMTKGSLLD 348
Query 989 YLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ ++ + KI DFGLA
Sbjct 349 FLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLA 408
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 409 RLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR------ 460
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ M + E +ERG R+P P CP ++ LMK CW+ + RPTFE +
Sbjct 461 --------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYI 512
Query 1166 IPILK 1170
L+
Sbjct 513 QSFLE 517
Score = 73.6 bits (179), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 61/217 (28%), Positives = 98/217 (45%), Gaps = 18/217 (8%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
AF + A +M ++ H L ++ V P I VTE++ G L +L+ G ++V
Sbjct 306 AFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEFMTKGSLLDFLKEGEGKFLKLPQLV 364
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
+A Q+A ++Y+E N +H ++ NIL+ G + K++D G+ E
Sbjct 365 DMAAQIADGMAYIERMNYIHRDLRAANILV-------GDNLVCKIADFGLARLIEDNEYT 417
Query 773 VER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
+ I W APE G ++ + D W FG L E+ G P E
Sbjct 418 ARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKGRVPYPGMVNREVLEQV 475
Query 828 QRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
+R +R+P P CP+ L L C +P +RP+F I
Sbjct 476 ERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYI 512
>sp|P10447|ABL_FSVHY Tyrosine-protein kinase transforming protein
Abl OS=Feline sarcoma virus (strain Hardy-Zuckerman 2) OX=11776
GN=ABL PE=2 SV=1
Length=439
Score = 144 bits (364), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 98/290 (34%), Positives = 142/290 (49%), Gaps = 27/290 (9%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
TV SP D + + LG G +G+V Y+ VAVK LK D
Sbjct 173 TVYGVSPNYDKWEMERTDITMKHKLGGGQYGEV----YEGVWKKYSLTVAVKTLKEDT-- 226
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSI 995
+ +E +++ + H ++++ G C E ++ E++ G+L DYL R +
Sbjct 227 MEVEEFLKEAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLDYLRECNRQEV 284
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
LL A QI M YL +++IHRDLAARN L+ + LVK+ DFGL++ + + Y
Sbjct 285 NAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT--GDTY 342
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
P+ W APE L KF SDVW+FGV L+E+ T+ SP GI
Sbjct 343 TAHAGTKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATY---GMSP------YPGID 393
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
Q + ELLE+ R+ RP+ CP +VY LM+ CW+ S RP F +
Sbjct 394 LSQ-----VYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPAFAEI 438
Score = 99.8 bits (247), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 78/287 (27%), Positives = 125/287 (44%), Gaps = 42/287 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+++ +IT LG G VYEG + L V +K
Sbjct 186 MERTDITMKHKLGGGQYGEVYEGVWK------------------------KYSLTVAVKT 221
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702
L ++ F + A++M ++ H +L + GVC R P ++TE++ +G L +LR
Sbjct 222 LKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECN 280
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
R V + +A Q++SA+ YLE KN +H ++ RN L+ G + +K++D G+
Sbjct 281 RQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV-------GENHLVKVADFGL 333
Query 763 G---LGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
G + P W APE L N S D W FG L EI G +P
Sbjct 334 SRLMTGDTYTAHAGTKFPIKWTAPESL--AYNKFSIKSDVWAFGVLLWEIATYGMSPYPG 391
Query 818 RSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTI 862
S+ ++ +R+ P CP+ + L C + P+ RP+F I
Sbjct 392 IDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPAFAEI 438
>sp|Q1KL86|EPHA2_MACFA Ephrin type-A receptor 2 OS=Macaca fascicularis
OX=9541 GN=EPHA2 PE=2 SV=1
Length=976
Score = 150 bits (379), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 87/283 (31%), Positives = 145/283 (51%), Gaps = 20/283 (7%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEI 948
T H + + + +G G FG+V T+ G E+ VA+K LKA + R + E
Sbjct 606 TEIHPSCVTRQKVIGAGEFGEVYKGTLK-TSSGKKEVPVAIKTLKAGYTEKQRVDFLGEA 664
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006
I+ H +II+ +G K + ++ E++ G+L +L + QL+ +
Sbjct 665 GIMGQFSHHNIIRLEGVISKY--KPMMIITEFMENGALDKFLREKDGEFSVLQLVGMLRG 722
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+
Sbjct 723 IAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIR 782
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE + KF ASDVWSFG+ ++E++T+ + +++ + +
Sbjct 783 WTAPEAISYRKFTSASDVWSFGIVMWEVMTYGER--------------PYWELSNHEVMK 828
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ G RLP P CP +Y LM CW+ E + RP F +++ IL
Sbjct 829 AINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSIL 871
Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 82/306 (27%), Positives = 133/306 (43%), Gaps = 41/306 (13%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+T+ +G G VY+G L+ GK +E+ V +K L +
Sbjct 613 VTRQKVIGAGEFGEVYKGTLKTSS------GK--------------KEVPVAIKTLKAGY 652
Query 649 HDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
+ + F A +M Q SH ++ + GV + +++TE++E+G LD +LR + G
Sbjct 653 TEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEFMENGALDKFLREKDGEFS 712
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
+ + + + +A+ + YL N N VH ++ RNIL+ ++ K+SD G+
Sbjct 713 VLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILV-------NSNLVCKVSDFGLSRVLE 765
Query 768 SREERVE-----RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
E +IP W APE + ++A D W FG + E+ GE P S
Sbjct 766 DDPEATYTTSGGKIPIRWTAPEAI--SYRKFTSASDVWSFGIVMWEVMTYGERPYWELSN 823
Query 821 SEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLAD 876
E RLP P CP + L QC E +RP F I+ L +L P +L
Sbjct 824 HEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKT 883
Query 877 VLTVNP 882
+ +P
Sbjct 884 LADFDP 889
>sp|Q09YN5|MET_RABIT Hepatocyte growth factor receptor OS=Oryctolagus
cuniculus OX=9986 GN=MET PE=3 SV=1
Length=1382
Score = 150 bits (380), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 98/284 (35%), Positives = 146/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + T+ + G+
Sbjct 1305 QPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISTIFSTFIGE 1348
Score = 62.0 bits (149), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1295 VYLLQGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISTI 1341
>sp|O02466|ILPR_BRALA Insulin-like peptide receptor OS=Branchiostoma
lanceolatum OX=7740 PE=2 SV=1
Length=1363
Score = 150 bits (380), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 108/327 (33%), Positives = 160/327 (49%), Gaps = 53/327 (16%)
Query 879 TVNPDSPASDPTVFHKRY------LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKA 931
+VNP+ +SD + + IR+LG+G FG V D D VAVK
Sbjct 970 SVNPEYMSSDDVYVPDEWEVPREKITLIRELGQGSFGMVYEGEAKDVVKDEPMVSVAVKT 1029
Query 932 LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP 991
+ + R + E +++T H++K G +G+ +L +VME + LG L++YL
Sbjct 1030 VNESASIRERIEFLNEASVMKTFNCHHVVKLMGVVS-KGQPTL-VVMELMALGDLKNYLR 1087
Query 992 RH----SIGLAQ-------------------------LLLFAQQICEGMAYLHAQHYIHR 1022
RH +GL+ ++ A I +GM+YL A+ ++HR
Sbjct 1088 RHRPEEDVGLSDSPASNEAKNSPFAENDNDLPPTFKDIIQMAGVIADGMSYLAAKKFVHR 1147
Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082
DLA RN ++ DR VKIGDFG+ + + E +YYR G PV W +PE LK F S
Sbjct 1148 DLACRNCMVAQDRTVKIGDFGMTRDIYET-DYYRKGGKGLLPVRWMSPESLKVGVFTSQS 1206
Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
DVWS+GV L+E+ T S P QG+ L +++ G L +P+ CP
Sbjct 1207 DVWSYGVVLWEMATLA----SQP---------YQGKSNEEVLKFVIDGG-MLEKPEGCPN 1252
Query 1143 EVYHLMKNCWETEASFRPTFENLIPIL 1169
++Y LMK CW+ S RPTF ++ IL
Sbjct 1253 KLYDLMKLCWQYRQSMRPTFLEIVEIL 1279
Score = 73.2 bits (178), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 80/326 (25%), Positives = 133/326 (41%), Gaps = 65/326 (20%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +++IT + LGQG+ VYEG E + ++P+V V +K
Sbjct 989 VPREKITLIRELGQGSFGMVYEG----------EAKDVVKDEPMV---------SVAVKT 1029
Query 644 LDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
++ S + F AS+M + H+ + GV +G ++V E + G L +LRR
Sbjct 1030 VNESASIRERIEFLNEASVMKTFNCHHVVKLMGVVSKGQPTLVVMELMALGDLKNYLRRH 1089
Query 703 R-------------------------GHVPMAWKMVV--AQQLASALSYLENKNLVHGNV 735
R +P +K ++ A +A +SYL K VH ++
Sbjct 1090 RPEEDVGLSDSPASNEAKNSPFAENDNDLPPTFKDIIQMAGVIADGMSYLAAKKFVHRDL 1149
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGAN 789
RN ++A+ +K+ D G+ + + + + W++PE L G
Sbjct 1150 ACRNCMVAQ-------DRTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKVGV- 1201
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQ 847
++ D W +G L E+ P Q +S E F L +P CP +L L
Sbjct 1202 -FTSQSDVWSYGVVLWEMATLASQPYQGKSNEEVLKFVIDGGMLEKPEGCPNKLYDLMKL 1260
Query 848 CLTYEPTQRPSFRTILRDLT-RLQPH 872
C Y + RP+F I+ L+ LQ H
Sbjct 1261 CWQYRQSMRPTFLEIVEILSPELQAH 1286
>sp|P16056|MET_MOUSE Hepatocyte growth factor receptor OS=Mus
musculus OX=10090 GN=Met PE=1 SV=1
Length=1379
Score = 150 bits (380), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 147/284 (52%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L + S + E I++ H ++
Sbjct 1082 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNV 1137
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1138 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1196
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1197 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1255
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1256 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITIYLLQGRRLL 1301
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + ++ + G+
Sbjct 1302 QPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISSIFSTFIGE 1345
Score = 62.0 bits (149), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1122 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1180
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1181 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1233
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1234 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1291
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1292 IYLLQGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISSI 1338
>sp|P27446|FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiphophorus
hellerii OX=8084 GN=fyn PE=2 SV=3
Length=537
Score = 146 bits (368), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 92/277 (33%), Positives = 140/277 (51%), Gaps = 29/277 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ I+ LG G FG+V + ++ T VAVK LK G + +E I++ L H
Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGTTK-----VAVKTLKP--GTMSPESFLEEAQIMKKLRH 323
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013
+ +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY
Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 380
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ +YIHRDL + N+L+ ++ + KI DFGLA+ + + Y R+ P+ W APE
Sbjct 381 IERMNYIHRDLRSANILVGDNLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+F SDVWSFG+ L EL+T + M + E +ERG R
Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+P P CP ++ LM CW+ + RPTFE L L+
Sbjct 485 MPCPQDCPASLHELMLQCWKKDPEERPTFEYLQAFLE 521
Score = 78.6 bits (192), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 66/230 (29%), Positives = 104/230 (45%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L
Sbjct 295 KVAVKTLKPGTMSPE-SFLEEAQIMKKLRHDKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 352
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G + K
Sbjct 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GDNLVCK 405
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
P + E +R +R+P P CP L L QC +P +RP+F
Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPASLHELMLQCWKKDPEERPTF 513
>sp|Q9VZI2|ACK_DROME Activated Cdc42 kinase Ack OS=Drosophila
melanogaster OX=7227 GN=Ack PE=1 SV=2
Length=1073
Score = 150 bits (378), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 97/287 (34%), Positives = 148/287 (52%), Gaps = 22/287 (8%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEI 948
+ H++ + LG+G FG V + + G VAVK LK+D P + +E+
Sbjct 117 LIHEKDITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREV 176
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQ 1005
+ L H ++++ G Q + ++ E GSL D L RH+ L + ++
Sbjct 177 QAMHALDHANLVRLYGVVLSQ---PMMMITELAERGSLLDTLRKQCRHT-SLTIIWNWSV 232
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
QI GMAYL + ++HRDLA RNVLL +KIGDFGL +A+P+ + Y + E P
Sbjct 233 QIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPF 292
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
W APE L+ +F +ASD W FGVTL+E+ + + +G+ Q+ L
Sbjct 293 PWCAPESLRFRQFSHASDTWMFGVTLWEMFSFGEDP---------WVGLNGSQI----LR 339
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
++ GERL +PD CP +VY +M CW+ + RPTF L L ++
Sbjct 340 KIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYLASM 386
Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 72/245 (29%), Positives = 110/245 (45%), Gaps = 26/245 (11%)
Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
VLK + + I F+ M + H +L ++GV + P +M+TE E G L L
Sbjct 157 VLKSDNLTQPGIIDDFFREVQAMHALDHANLVRLYGVVLSQPM-MMITELAERGSLLDTL 215
Query 700 RRERGHVPMA--WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
R++ H + W V Q+ + ++YLE K +H ++ RN+LLA IK+
Sbjct 216 RKQCRHTSLTIIWNWSV--QIVTGMAYLEQKRFLHRDLACRNVLLA-------AGNKIKI 266
Query 758 SDPGVGLGALSREE--------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
D G+ + AL +E+ + PW APE L S A D W FG TL E+
Sbjct 267 GDFGL-MRALPQEDDCYVMSEHKKVPFPWCAPESL--RFRQFSHASDTWMFGVTLWEMFS 323
Query 810 DGEAPLQSRSPSEKEHFYQRQ-HRLPEPSC--PQLATLTSQCLTYEPTQRPSFRTILRDL 866
GE P + S+ R+ RL +P P + + QC P +RP+F + L
Sbjct 324 FGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYL 383
Query 867 TRLQP 871
+ P
Sbjct 384 ASMSP 388
>sp|P09324|YES_CHICK Tyrosine-protein kinase Yes OS=Gallus gallus
OX=9031 GN=YES1 PE=1 SV=3
Length=541
Score = 146 bits (368), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 101/305 (33%), Positives = 150/305 (49%), Gaps = 32/305 (10%)
Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
H L V TV P + A D + L+ LG+G FG+V + ++ T VA
Sbjct 247 HKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK-----VA 301
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL D
Sbjct 302 IKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVVS---EEPIYIVTEFMTKGSLLD 356
Query 989 YLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ ++ + KI DFGLA
Sbjct 357 FLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLA 416
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 417 RLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR------ 468
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ M + E +ERG R+P P CP ++ LMK CW+ + RPTFE +
Sbjct 469 --------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYI 520
Query 1166 IPILK 1170
L+
Sbjct 521 QSFLE 525
Score = 76.6 bits (187), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 65/233 (28%), Positives = 105/233 (45%), Gaps = 19/233 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P + AF + A +M ++ H L ++ V P I VTE++ G L
Sbjct 299 KVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEFMTKGSLLD 356
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G ++V +A Q+A ++Y+E N +H ++ NIL+ G + K
Sbjct 357 FLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILV-------GDNLVCK 409
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 410 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 467
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
P E +R +R+P P CP+ L L C +P +RP+F I
Sbjct 468 RVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYI 520
>sp|P29321|EPHA8_RAT Ephrin type-A receptor 8 (Fragment) OS=Rattus
norvegicus OX=10116 GN=Epha8 PE=2 SV=1
Length=372
Score = 142 bits (358), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 89/264 (34%), Positives = 136/264 (52%), Gaps = 19/264 (7%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VA+KALKA + R + +E I+ H +II+ +G +G ++ +V EY+ GSL
Sbjct 31 VAIKALKAGYTERQRQDFLREAAIMGQFDHPNIIRLEGVVT-RGRLAM-IVTEYMENGSL 88
Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L H + QL+ + + GM YL YIHRDLAARN+L+D + K+ DFGL
Sbjct 89 DAFLRTHDGQFTILQLVGMLKGVGAGMRYLSDLGYIHRDLAARNILVDGRLVCKVSDFGL 148
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
++A+ + E G P+ W APE + F ASDVWSFGV ++E+L + +
Sbjct 149 SRALEDDPEAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYW- 207
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
MT + +E G RLP P CP ++ LM +CW + + RP F +
Sbjct 208 -------------NMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFSH 254
Query 1165 LIPILKT-VHEKYQGQAPSVFSVC 1187
++ +L+ VH +A + S C
Sbjct 255 VVSVLEALVHSPESLRATATVSRC 278
Score = 89.4 bits (220), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 80/286 (28%), Positives = 132/286 (46%), Gaps = 28/286 (10%)
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSH 667
++ GSG E G++ VPG+ +++ V +K L + + F A++M Q H
Sbjct 6 KIIGSG--ESGEVCYGRLQVPGQ---RDVPVAIKALKAGYTERQRQDFLREAAIMGQFDH 60
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
++ + GV RG ++VTEY+E+G LD +LR G + + + + + + + YL +
Sbjct 61 PNIIRLEGVVTRGRLAMIVTEYMENGSLDAFLRTHDGQFTILQLVGMLKGVGAGMRYLSD 120
Query 728 KNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIP--WL 779
+H ++ RNIL+ RL K+SD G+ E +IP W
Sbjct 121 LGYIHRDLAARNILVDGRL--------VCKVSDFGLSRALEDDPEAAYTTAGGKIPIRWT 172
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838
APE + + S+A D W FG + E+ GE P + + + + +RLP P C
Sbjct 173 APEAI--AFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNQDVISSVEEGYRLPAPMGC 230
Query 839 PQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVLTVN 881
P+ L L C + QRP F ++ L L P +L TV+
Sbjct 231 PRALHQLMLDCWHKDRAQRPRFSHVVSVLEALVHSPESLRATATVS 276
>sp|P04412|EGFR_DROME Epidermal growth factor receptor OS=Drosophila
melanogaster OX=7227 GN=Egfr PE=1 SV=3
Length=1426
Score = 150 bits (379), Expect = 3e-35, Method: Compositional matrix adjust.
Identities = 94/275 (34%), Positives = 142/275 (52%), Gaps = 20/275 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+K LG G FG+V + P + VA+K L G + + +E I+ + H
Sbjct 938 LRKGGVLGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASEEH 997
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYL 1014
+++K C + L+ + +PLG L DY+ R IG LL ++ QI +GM+YL
Sbjct 998 VNLLKLLAVCM---SSQMMLITQLMPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYL 1054
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+ +HRDLAARNVL+ LVKI DFGLAK + Y+ G P+ W A EC++
Sbjct 1055 EEKRLVHRDLAARNVLVQTPSLVKITDFGLAKLLSSDSNEYKA-AGGKMPIKWLALECIR 1113
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
F SDVW+FGVT++ELLT Q P + + +L+E G +L
Sbjct 1114 NRVFTSKSDVWAFGVTIWELLTF---GQRP-----------HENIPAKDIPDLIEVGLKL 1159
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+P+ C ++Y + +CW +A+ RPTF+ L +
Sbjct 1160 EQPEICSLDIYCTLLSCWHLDAAMRPTFKQLTTVF 1194
Score = 71.2 bits (173), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 93/413 (23%), Positives = 161/413 (39%), Gaps = 78/413 (19%)
Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
P + + V E+ + LG G VY+G EG E+ +P
Sbjct 920 PSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPEG-----------ENVKIP- 967
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
+ ++L + + + F A +M+ H +L + VC+ + +++T+ +
Sbjct 968 -------VAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKLLAVCMSS-QMMLITQLM 1019
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L ++R R + + + Q+A +SYLE K LVH ++ RN+L+
Sbjct 1020 PLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLVQ------- 1072
Query 751 TSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGATL 804
T +K++D G+ L + S E + I WLA EC+ ++ D W FG T+
Sbjct 1073 TPSLVKITDFGLAKLLSSDSNEYKAAGGKMPIKWLALECIRNRV--FTSKSDVWAFGVTI 1130
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL---ATLTSQCLTYEPTQRPSFRT 861
E+ G+ P ++ + + +L +P L TL S C + RP+F+
Sbjct 1131 WELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLS-CWHLDAAMRPTFKQ 1189
Query 862 IL-------RD-----------LTRLQPHNLAD----VLTVNPDSPASDPTVFHKRYLKK 899
+ RD TRL + D + + P + S+ YL+
Sbjct 1190 LTTVFAEFARDPGRYLAIPGDKFTRLPAYTSQDEKDLIRKLAPTTDGSEAIAKPDDYLQP 1249
Query 900 IRDLGEGH-------FGKVSLYCYDPTN----------DGTGEMVAVKALKAD 935
G H K++ YC DP+N D + V V L+ D
Sbjct 1250 KAAPGPSHRTDCTDEMPKLNRYCKDPSNKNSSTGDDERDSSAREVGVGNLRLD 1302
>sp|P00521|ABL_MLVAB Tyrosine-protein kinase transforming protein
Abl OS=Abelson murine leukemia virus OX=11788 GN=ABL PE=3
SV=1
Length=746
Score = 148 bits (374), Expect = 3e-35, Method: Compositional matrix adjust.
Identities = 96/292 (33%), Positives = 148/292 (51%), Gaps = 35/292 (12%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
+D T+ HK LG G +G+V Y+ VAVK LK D + +
Sbjct 126 TDITMKHK--------LGGGQYGEV----YEGVWKKYSLTVAVKTLKEDT--MEVEEFLK 171
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLF 1003
E +++ + H ++++ G C E ++ E++ G+L DYL R + LL
Sbjct 172 EAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYM 229
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
A QI M YL +++IHRDLAARN L+ + LVK+ DFGL++ + + Y
Sbjct 230 ATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDTYTAHAGAKF 287
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
P+ W APE L KF SDVW+FGV L+E+ T+ S P ++L +
Sbjct 288 PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMS----PYPGIDLS----------Q 333
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+ ELLE+ R+ RP+ CP +VY LM+ CW+ S RP+F + +T+ ++
Sbjct 334 VYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 385
Score = 99.4 bits (246), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 73/249 (29%), Positives = 118/249 (47%), Gaps = 19/249 (8%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
L V +K L ++ F + A++M ++ H +L + GVC R P ++TE++ +G L
Sbjct 152 LTVAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLL 210
Query 697 VWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+LR R V + +A Q++SA+ YLE KN +H ++ RN L+ G + +
Sbjct 211 DYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV-------GENHLV 263
Query 756 KLSDPGVG---LGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ G + P W APE L N S D W FG L EI
Sbjct 264 KVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESL--AYNKFSIKSDVWAFGVLLWEIATY 321
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL-T 867
G +P S+ ++ +R+ P CP+ + L C + P+ RPSF I + T
Sbjct 322 GMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFET 381
Query 868 RLQPHNLAD 876
Q +++D
Sbjct 382 MFQESSISD 390
>sp|P10936|YES_XENLA Tyrosine-protein kinase Yes OS=Xenopus laevis
OX=8355 GN=yes1 PE=2 SV=3
Length=537
Score = 145 bits (366), Expect = 4e-35, Method: Compositional matrix adjust.
Identities = 94/276 (34%), Positives = 142/276 (51%), Gaps = 39/276 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+V + ++ T VA+K LK G + QE I++ L H+ ++
Sbjct 277 LGQGCFGEVWIGTWNGTTK-----VAIKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPL 329
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHY 1019
E+ + +V EY+ GSL D+L + + L QL+ A QI +GMAY+ +Y
Sbjct 330 YAVVS---EEPIYIVTEYMIKGSLLDFLKEGNGKYLKLPQLVDMAAQIADGMAYIERMNY 386
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRDL A N+L+ ++ + KI DFGLA+ + + Y R+ P+ W APE +F
Sbjct 387 IHRDLRAANILVGDNLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFT 444
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ-----MTVLRLTELLERGERL 1134
SDVWSFG+ L EL +A+G+ M + E +ERG R+
Sbjct 445 IKSDVWSFGILLTEL-------------------VAKGRVPYPGMVNREVLEQVERGYRM 485
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
P P +CP ++ LMK CW+ + RPTFE + L+
Sbjct 486 PCPQRCPESLHELMKLCWKKDPDERPTFEYIQSFLE 521
Score = 77.0 bits (188), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 65/233 (28%), Positives = 106/233 (45%), Gaps = 19/233 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P + AF + A +M ++ H L ++ V P I VTEY+ G L
Sbjct 295 KVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEYMIKGSLLD 352
Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G ++ + + +A Q+A ++Y+E N +H ++ NIL+ G + K
Sbjct 353 FLKEGNGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILV-------GDNLVCK 405
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVAKG 463
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTI 862
P E +R +R+P P CP+ L L C +P +RP+F I
Sbjct 464 RVPYPGMVNREVLEQVERGYRMPCPQRCPESLHELMKLCWKKDPDERPTFEYI 516
>sp|Q90330|FGFR4_COTCO Fibroblast growth factor receptor 4 OS=Coturnix
coturnix OX=9091 GN=FGFR4 PE=2 SV=1
Length=713
Score = 147 bits (372), Expect = 4e-35, Method: Compositional matrix adjust.
Identities = 106/323 (33%), Positives = 158/323 (49%), Gaps = 42/323 (13%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKAD 935
V D P F + L + LGEG FG+V Y D VAVK LK +
Sbjct 361 VVEMDLPLDSKWEFPREKLVLGKPLGEGCFGQVVRAEAYGIDRQWPDRAVTVAVKMLKDN 420
Query 936 CGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---- 990
+ + E+++++ + H++II G C G L +++E+ G+LR+YL
Sbjct 421 ATDKDLADLISEMEMMKLMDKHKNIINLLGVCTQDG--PLYVIVEFAAKGNLREYLRARR 478
Query 991 ---PRHSIGLAQL----LLFAQ------QICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037
P ++ + +L L F Q+ GM YL ++ IHRDLAARNVL+ + ++
Sbjct 479 PPTPDYTFDITELHEEQLCFKDLVSCVYQVARGMEYLESRRCIHRDLAARNVLVTAENVM 538
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
KI DFGLA+ V +YY+ +G PV W APE L + + + SDVWSFG+ ++E+ T
Sbjct 539 KIADFGLARDV-HDIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILMWEIFT- 596
Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157
L G + V L +LL+ G R+ P C E+Y LM+ CW
Sbjct 597 -------------LGGSPYPGIPVEELFKLLKEGHRMDCPSNCTHELYMLMRECWHAVPL 643
Query 1158 FRPTFENLI----PILKTVHEKY 1176
RPTF+ L+ IL + E+Y
Sbjct 644 QRPTFKQLVEGLDKILAAISEEY 666
Score = 65.1 bits (157), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 63/261 (24%), Positives = 112/261 (43%), Gaps = 32/261 (12%)
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
DR + V + + + D+A E + H ++ + GVC + ++ E+
Sbjct 407 DRAVTVAVKMLKDNATDKDLADLISEMEMMKLMDKHKNIINLLGVCTQDGPLYVIVEFAA 466
Query 692 HGPLDVWLRRERGHVP-------------MAWKMVVA--QQLASALSYLENKNLVHGNVC 736
G L +LR R P + +K +V+ Q+A + YLE++ +H ++
Sbjct 467 KGNLREYLRARRPPTPDYTFDITELHEEQLCFKDLVSCVYQVARGMEYLESRRCIHRDLA 526
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANS 790
RN+L+ AE +K++D G+ ++ R+P W+APE L +
Sbjct 527 ARNVLVT----AENV---MKIADFGLARDVHDIDYYKKTSNGRLPVKWMAPEALFDRVYT 579
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQC 848
+ D W FG + EI G +P E + HR+ PS C +L L +C
Sbjct 580 HQS--DVWSFGILMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDCPSNCTHELYMLMREC 637
Query 849 LTYEPTQRPSFRTILRDLTRL 869
P QRP+F+ ++ L ++
Sbjct 638 WHAVPLQRPTFKQLVEGLDKI 658
>sp|Q2QLH6|MET_OTOGA Hepatocyte growth factor receptor OS=Otolemur
garnettii OX=30611 GN=MET PE=3 SV=1
Length=1382
Score = 150 bits (378), Expect = 4e-35, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 146/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD + VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDENFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348
Score = 62.4 bits (150), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 101/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L + +K++D G+ +E
Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------NFTVKVADFGLARDMYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341
>sp|A1A5H8|YES_DANRE Tyrosine-protein kinase yes OS=Danio rerio
OX=7955 GN=yes1 PE=1 SV=1
Length=546
Score = 145 bits (365), Expect = 6e-35, Method: Compositional matrix adjust.
Identities = 106/334 (32%), Positives = 159/334 (48%), Gaps = 42/334 (13%)
Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVL---------TVNPDSP--ASDPTVFHKRYLKK 899
Y T R F T+ + + H AD L TV P + A D + L+
Sbjct 225 YYITTRAQFDTLQKLVKHYTEH--ADGLCYRLTTVCPTVKPQTQGLAKDAWEIPRESLRL 282
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG+V + ++ T VA+K LK G + QE I++ L H+ +
Sbjct 283 ELKLGQGCFGEVWMGTWNGTTK-----VAIKTLKP--GTMSPEAFLQEAQIMKKLRHDKL 335
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA 1016
+ E+ + +V EY+ GSL D+L + L QL+ A QI +GMA++
Sbjct 336 VPLYAVVS---EEPIYIVTEYMGKGSLLDFLKEGEGKYLKLPQLVDMAAQIADGMAFIER 392
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+YIHRDL A N+L+ ++ + KI DFGLA+ + + Y R+ P+ W APE
Sbjct 393 MNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYG 450
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+F SDVWSFG+ L EL+T + M + E +ERG R+P
Sbjct 451 RFTIKSDVWSFGILLTELVTKGR--------------VPYPGMVNREVLEQVERGYRMPC 496
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
P CP ++ +M+ CW+ E RPTFE + L+
Sbjct 497 PQGCPESLHEMMRLCWKKEPDERPTFEYIQSFLE 530
Score = 75.1 bits (183), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 64/233 (27%), Positives = 105/233 (45%), Gaps = 19/233 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P AF + A +M ++ H L ++ V P I VTEY+ G L
Sbjct 304 KVAIKTLKPGTMSPE-AFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEYMGKGSLLD 361
Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G ++ + + +A Q+A ++++E N +H ++ NIL+ G + K
Sbjct 362 FLKEGEGKYLKLPQLVDMAAQIADGMAFIERMNYIHRDLRAANILV-------GDNLVCK 414
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 415 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 472
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
P E +R +R+P P CP+ L + C EP +RP+F I
Sbjct 473 RVPYPGMVNREVLEQVERGYRMPCPQGCPESLHEMMRLCWKKEPDERPTFEYI 525
>sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens
OX=9606 GN=ABL1 PE=1 SV=4
Length=1130
Score = 149 bits (375), Expect = 6e-35, Method: Compositional matrix adjust.
Identities = 97/300 (32%), Positives = 149/300 (50%), Gaps = 27/300 (9%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
TV SP D + + LG G +G+V Y+ VAVK LK D
Sbjct 224 TVYGVSPNYDKWEMERTDITMKHKLGGGQYGEV----YEGVWKKYSLTVAVKTLKEDT-- 277
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSI 995
+ +E +++ + H ++++ G C E ++ E++ G+L DYL R +
Sbjct 278 MEVEEFLKEAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLDYLRECNRQEV 335
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
LL A QI M YL +++IHRDLAARN L+ + LVK+ DFGL++ + + Y
Sbjct 336 NAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDTY 393
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
P+ W APE L KF SDVW+FGV L+E+ T+ S P ++L
Sbjct 394 TAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMS----PYPGIDLS--- 446
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
++ ELLE+ R+ RP+ CP +VY LM+ CW+ S RP+F + +T+ ++
Sbjct 447 -------QVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 499
Score = 98.2 bits (243), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 73/249 (29%), Positives = 118/249 (47%), Gaps = 19/249 (8%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
L V +K L ++ F + A++M ++ H +L + GVC R P ++TE++ +G L
Sbjct 266 LTVAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLL 324
Query 697 VWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+LR R V + +A Q++SA+ YLE KN +H ++ RN L+ G + +
Sbjct 325 DYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV-------GENHLV 377
Query 756 KLSDPGVG---LGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ G + P W APE L N S D W FG L EI
Sbjct 378 KVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESL--AYNKFSIKSDVWAFGVLLWEIATY 435
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL-T 867
G +P S+ ++ +R+ P CP+ + L C + P+ RPSF I + T
Sbjct 436 GMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFET 495
Query 868 RLQPHNLAD 876
Q +++D
Sbjct 496 MFQESSISD 504
>sp|Q04912|RON_HUMAN Macrophage-stimulating protein receptor OS=Homo
sapiens OX=9606 GN=MST1R PE=1 SV=3
Length=1400
Score = 149 bits (376), Expect = 6e-35, Method: Compositional matrix adjust.
Identities = 97/285 (34%), Positives = 151/285 (53%), Gaps = 24/285 (8%)
Query 888 DPTVFHKRYLK-KIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWK 945
D + H+R + R +G+GHFG V Y + + + A+K+L Q +
Sbjct 1072 DVLIPHERVVTHSDRVIGKGHFGVV--YHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFL 1129
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLF 1003
+E ++R L H +++ G E +++ Y+ G L ++ P+ + + L+ F
Sbjct 1130 REGLLMRGLNHPNVLALIGIMLPP-EGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISF 1188
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
Q+ GM YL Q ++HRDLAARN +LD VK+ DFGLA+ + + EYY V++ +
Sbjct 1189 GLQVARGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILD-REYYSVQQHRHA 1247
Query 1064 --PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
PV W A E L+ Y+F SDVWSFGV L+ELLT +PP + ++
Sbjct 1248 RLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTR----GAPPYRHID----------P 1293
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
LT L +G RLP+P+ CP +Y +M+ CWE + + RPTF L+
Sbjct 1294 FDLTHFLAQGRRLPQPEYCPDSLYQVMQQCWEADPAVRPTFRVLV 1338
Score = 76.6 bits (187), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 64/235 (27%), Positives = 108/235 (46%), Gaps = 22/235 (9%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENI--MVTEYVEHGPLDVWLRRERGHVPMAWK 711
AF LM ++H ++ + G+ + PE + ++ Y+ HG L ++R + + +
Sbjct 1127 AFLREGLLMRGLNHPNVLALIGIMLP-PEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDL 1185
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE- 770
+ Q+A + YL + VH ++ RN +L S +K++D G+ L RE
Sbjct 1186 ISFGLQVARGMEYLAEQKFVHRDLAARNCMLDE-------SFTVKVADFGLARDILDREY 1238
Query 771 -----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
R R+P W+A E L +T D W FG L E+ G P + P +
Sbjct 1239 YSVQQHRHARLPVKWMALESL--QTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDL 1296
Query 824 EHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
HF + RLP+P CP L + QC +P RP+FR ++ ++ ++ L D
Sbjct 1297 THFLAQGRRLPQPEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGD 1351
>sp|G5ECJ6|CSK1_CAEEL Tyrosine-protein kinase csk-1 OS=Caenorhabditis
elegans OX=6239 GN=csk-1 PE=1 SV=1
Length=539
Score = 144 bits (364), Expect = 7e-35, Method: Compositional matrix adjust.
Identities = 89/274 (32%), Positives = 138/274 (50%), Gaps = 31/274 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V L Y VA+K K G E + L H +++
Sbjct 289 IGHGEFGDVRLGTY------KNRKVALKVSKRH-GNGMLDSLLDEAKFMVGLSHPNLVTL 341
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
G D + ++ ++ EY+ G+L D L RH++ QL++FA IC+GM YL ++
Sbjct 342 VGVVLD--DVNVYMITEYMANGNLIDLLRSRGRHALERRQLMMFAMDICQGMCYLESKQI 399
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLA-KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRDLAARNVLLD+D + K+ DFGLA KA + H+ G P+ W APE L+ +F
Sbjct 400 VHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSHD----SASGKFPIKWTAPEALRHSQF 455
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SDVWSFG+ L+E+ + + ++ + + +E+G R+ P+
Sbjct 456 TTKSDVWSFGILLWEIFS--------------FGRVPYPRIPIQDVVRYIEKGYRMEAPE 501
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
CP E++ +M W A RP+F ++ L T+
Sbjct 502 GCPPEIFKVMNETWALSAQDRPSFGQVLQRLTTI 535
Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 67/241 (28%), Positives = 111/241 (46%), Gaps = 18/241 (7%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V LKV + + + + A M +SH +L + GV + M+TEY+ +G L +
Sbjct 306 KVALKVSKRHGNGMLDSLLDEAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMANGNL-I 364
Query 698 WLRRERGHVPMAWK--MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
L R RG + + M+ A + + YLE+K +VH ++ RN+LL +A
Sbjct 365 DLLRSRGRHALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVA------- 417
Query 756 KLSDPGVGLGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
K+SD G+ A S+ I W APE L + +T D W FG L EI G
Sbjct 418 KVSDFGLAKKANSQSHDSASGKFPIKWTAPEALR--HSQFTTKSDVWSFGILLWEIFSFG 475
Query 812 EAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
P + + ++ +R+ PE P++ + ++ RPSF +L+ LT +
Sbjct 476 RVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRLTTI 535
Query 870 Q 870
+
Sbjct 536 R 536
>sp|Q60553|ERBB2_MESAU Receptor tyrosine-protein kinase erbB-2
OS=Mesocricetus auratus OX=10036 GN=ERBB2 PE=2 SV=1
Length=1254
Score = 149 bits (375), Expect = 7e-35, Method: Compositional matrix adjust.
Identities = 92/278 (33%), Positives = 142/278 (51%), Gaps = 20/278 (7%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+ + L+K++ LG G FG V + P + VA+K L+ + P+ E +
Sbjct 714 ILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYV 773
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQIC 1008
+ L ++ + G C ++QLV + +P G L D++ H +G LL + QI
Sbjct 774 MAGLGSPYVSRLLGICL---TSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIA 830
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+GM+YL +HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W
Sbjct 831 KGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWI 889
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A E + +F + SDVWS+GVT++EL+T GI + + +LL
Sbjct 890 ALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYD---------GIPARE-----IPDLL 935
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
E+GERLP+P C +VY +M CW ++ RP F L+
Sbjct 936 EKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELV 973
Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 76/342 (22%), Positives = 142/342 (42%), Gaps = 46/342 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+Q + + E+ ++ LG G VY+G +G E+ +P
Sbjct 708 NQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDG-----------ENVKIP------- 749
Query 637 LRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +KVL + A + A +M+ + +++ + G+C+ +VT+ + +G L
Sbjct 750 --VAIKVLRENTSPKANKEILDEAYVMAGLGSPYVSRLLGICLTSTVQ-LVTQLMPYGCL 806
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R RG + + Q+A +SYLE+ LVH ++ RN+L+ + +
Sbjct 807 LDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVK-------SPNHV 859
Query 756 KLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
K++D GL L + E I W+A E + + D W +G T+ E+
Sbjct 860 KITD--FGLARLLDIDETEYHADGGKVPIKWIALESI--LRRRFTHQSDVWSYGVTVWEL 915
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRD 865
G P E ++ RLP+P + + +C + RP FR ++ +
Sbjct 916 MTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSE 975
Query 866 LTRLQPHNLADVLTVNPDSPASDP--TVFHKRYLKKIRDLGE 905
+R+ V+ N D S P + F++ L+ D+G+
Sbjct 976 FSRMARDPQRFVVIQNEDLGPSSPLDSTFYRSLLED-DDMGD 1016
>sp|Q2QLF1|MET_PANTR Hepatocyte growth factor receptor OS=Pan
troglodytes OX=9598 GN=MET PE=3 SV=1
Length=1390
Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 61.6 bits (148), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>sp|Q2IBD8|MET_PONAB Hepatocyte growth factor receptor OS=Pongo
abelii OX=9601 GN=MET PE=3 SV=1
Length=1390
Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 61.6 bits (148), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>sp|Q2IBF2|MET_GORGO Hepatocyte growth factor receptor OS=Gorilla
gorilla gorilla OX=9595 GN=MET PE=3 SV=1
Length=1390
Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 61.6 bits (148), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>sp|Q2IBA6|MET_CHLAE Hepatocyte growth factor receptor OS=Chlorocebus
aethiops OX=9534 GN=MET PE=1 SV=1
Length=1381
Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 61.6 bits (148), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>sp|Q07DY1|MET_NOMLE Hepatocyte growth factor receptor OS=Nomascus
leucogenys OX=61853 GN=MET PE=3 SV=1
Length=1390
Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 61.6 bits (148), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFT-------VKVADFGLARDMYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>sp|P39688|FYN_MOUSE Tyrosine-protein kinase Fyn OS=Mus musculus
OX=10090 GN=Fyn PE=1 SV=4
Length=537
Score = 144 bits (363), Expect = 8e-35, Method: Compositional matrix adjust.
Identities = 91/277 (33%), Positives = 139/277 (50%), Gaps = 29/277 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ I+ LG G FG+V + ++ VA+K LK G + +E I++ L H
Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAIKTLKP--GTMSPESFLEEAQIMKKLKH 323
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013
+ +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY
Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 380
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ +YIHRDL + N+L+ N + KI DFGLA+ + + Y R+ P+ W APE
Sbjct 381 IERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+F SDVWSFG+ L EL+T + M + E +ERG R
Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+P P CP ++ LM +CW+ + RPTFE L L+
Sbjct 485 MPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLE 521
Score = 77.4 bits (189), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 65/230 (28%), Positives = 102/230 (44%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L
Sbjct 295 KVAIKTLKPGTMSPE-SFLEEAQIMKKLKHDKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 352
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G K
Sbjct 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GNGLICK 405
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
P + E +R +R+P P CP L L C +P +RP+F
Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 513
>sp|Q2QLC0|MET_PLEMO Hepatocyte growth factor receptor OS=Plecturocebus
moloch OX=9523 GN=MET PE=3 SV=1
Length=1381
Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 61.2 bits (147), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>sp|P08581|MET_HUMAN Hepatocyte growth factor receptor OS=Homo
sapiens OX=9606 GN=MET PE=1 SV=4
Length=1390
Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 61.6 bits (148), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>sp|Q2QL89|MET_MICMU Hepatocyte growth factor receptor OS=Microcebus
murinus OX=30608 GN=MET PE=3 SV=1
Length=1382
Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348
Score = 62.0 bits (149), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341
>sp|Q2IBG7|MET_EULMM Hepatocyte growth factor receptor OS=Eulemur
macaco macaco OX=30603 GN=MET PE=3 SV=1
Length=1382
Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348
Score = 61.6 bits (148), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341
>sp|A0M8R7|MET_PAPAN Hepatocyte growth factor receptor OS=Papio
anubis OX=9555 GN=MET PE=3 SV=1
Length=1381
Score = 148 bits (374), Expect = 8e-35, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 61.6 bits (148), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>sp|Q2QLG5|MET_CALJA Hepatocyte growth factor receptor OS=Callithrix
jacchus OX=9483 GN=MET PE=3 SV=1
Length=1381
Score = 148 bits (374), Expect = 9e-35, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 61.6 bits (148), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo sapiens
OX=9606 GN=FYN PE=1 SV=3
Length=537
Score = 144 bits (363), Expect = 9e-35, Method: Compositional matrix adjust.
Identities = 91/277 (33%), Positives = 139/277 (50%), Gaps = 29/277 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ I+ LG G FG+V + ++ VA+K LK G + +E I++ L H
Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAIKTLKP--GTMSPESFLEEAQIMKKLKH 323
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013
+ +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY
Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 380
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ +YIHRDL + N+L+ N + KI DFGLA+ + + Y R+ P+ W APE
Sbjct 381 IERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+F SDVWSFG+ L EL+T + M + E +ERG R
Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+P P CP ++ LM +CW+ + RPTFE L L+
Sbjct 485 MPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLE 521
Score = 77.4 bits (189), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 65/230 (28%), Positives = 102/230 (44%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L
Sbjct 295 KVAIKTLKPGTMSPE-SFLEEAQIMKKLKHDKLVQLYAVVSEEPIYI-VTEYMNKGSLLD 352
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G K
Sbjct 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GNGLICK 405
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
P + E +R +R+P P CP L L C +P +RP+F
Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 513
>sp|Q07DV8|MET_AOTNA Hepatocyte growth factor receptor OS=Aotus
nancymaae OX=37293 GN=MET PE=3 SV=1
Length=1381
Score = 148 bits (374), Expect = 9e-35, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS--PVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 61.2 bits (147), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>sp|Q09YH7|MET_SAIBB Hepatocyte growth factor receptor OS=Saimiri
boliviensis boliviensis OX=39432 GN=MET PE=3 SV=1
Length=1381
Score = 148 bits (374), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 61.2 bits (147), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>sp|Q07DZ1|MET_COLGU Hepatocyte growth factor receptor OS=Colobus
guereza OX=33548 GN=MET PE=3 SV=1
Length=1381
Score = 148 bits (374), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 61.6 bits (148), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>sp|A1Y2K1|FYN_PIG Tyrosine-protein kinase Fyn OS=Sus scrofa OX=9823
GN=FYN PE=2 SV=2
Length=537
Score = 144 bits (363), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 91/277 (33%), Positives = 139/277 (50%), Gaps = 29/277 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ I+ LG G FG+V + ++ VA+K LK G + +E I++ L H
Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAIKTLKP--GTMSPESFLEEAQIMKKLKH 323
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013
+ +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY
Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 380
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ +YIHRDL + N+L+ N + KI DFGLA+ + + Y R+ P+ W APE
Sbjct 381 IERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+F SDVWSFG+ L EL+T + M + E +ERG R
Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+P P CP ++ LM +CW+ + RPTFE L L+
Sbjct 485 MPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLE 521
Score = 77.4 bits (189), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 65/230 (28%), Positives = 102/230 (44%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L
Sbjct 295 KVAIKTLKPGTMSPE-SFLEEAQIMKKLKHDKLVQLYAVVSEEPIYI-VTEYMNKGSLLD 352
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G K
Sbjct 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GNGLICK 405
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
P + E +R +R+P P CP L L C +P +RP+F
Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 513
>sp|P00520|ABL1_MOUSE Tyrosine-protein kinase ABL1 OS=Mus musculus
OX=10090 GN=Abl1 PE=1 SV=3
Length=1123
Score = 148 bits (373), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 98/292 (34%), Positives = 147/292 (50%), Gaps = 35/292 (12%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
+D T+ HK LG G +G+V Y+ VAVK LK D + +
Sbjct 240 TDITMKHK--------LGGGQYGEV----YEGVWKKYSLTVAVKTLKEDT--MEVEEFLK 285
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLF 1003
E +++ + H ++++ G C E ++ E++ G+L DYL R + LL
Sbjct 286 EAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYM 343
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
A QI M YL +++IHRDLAARN L+ + LVK+ DFGL++ + + Y
Sbjct 344 ATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDTYTAHAGAKF 401
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
P+ W APE L KF SDVW+FGV L+E+ T+ SP GI Q
Sbjct 402 PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATY---GMSP------YPGIDLSQ----- 447
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+ ELLE+ R+ RP+ CP +VY LM+ CW+ S RP+F + +T+ ++
Sbjct 448 VYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 499
Score = 98.2 bits (243), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 73/249 (29%), Positives = 118/249 (47%), Gaps = 19/249 (8%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
L V +K L ++ F + A++M ++ H +L + GVC R P ++TE++ +G L
Sbjct 266 LTVAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLL 324
Query 697 VWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+LR R V + +A Q++SA+ YLE KN +H ++ RN L+ G + +
Sbjct 325 DYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV-------GENHLV 377
Query 756 KLSDPGVG---LGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ G + P W APE L N S D W FG L EI
Sbjct 378 KVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESL--AYNKFSIKSDVWAFGVLLWEIATY 435
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL-T 867
G +P S+ ++ +R+ P CP+ + L C + P+ RPSF I + T
Sbjct 436 GMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFET 495
Query 868 RLQPHNLAD 876
Q +++D
Sbjct 496 MFQESSISD 504
>sp|Q09YL1|MET_ATEGE Hepatocyte growth factor receptor OS=Ateles
geoffroyi OX=9509 GN=MET PE=3 SV=1
Length=1381
Score = 148 bits (374), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T NDG AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSAFIGE 1347
Score = 61.2 bits (147), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>sp|Q62844|FYN_RAT Tyrosine-protein kinase Fyn OS=Rattus norvegicus
OX=10116 GN=Fyn PE=1 SV=1
Length=537
Score = 144 bits (362), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 91/277 (33%), Positives = 139/277 (50%), Gaps = 29/277 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ I+ LG G FG+V + ++ VA+K LK G + +E I++ L H
Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAIKTLKP--GTMSPESFLEEAQIMKKLKH 323
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013
+ +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY
Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 380
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ +YIHRDL + N+L+ N + KI DFGLA+ + + Y R+ P+ W APE
Sbjct 381 IERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+F SDVWSFG+ L EL+T + M + E +ERG R
Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+P P CP ++ LM +CW+ + RPTFE L L+
Sbjct 485 MPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLE 521
Score = 77.4 bits (189), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 65/230 (28%), Positives = 102/230 (44%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L
Sbjct 295 KVAIKTLKPGTMSPE-SFLEEAQIMKKLKHDKLVQLYAVVSEEPIYI-VTEYMNKGSLLD 352
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G K
Sbjct 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GNGLICK 405
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
P + E +R +R+P P CP L L C +P +RP+F
Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 513
>sp|A0JNB0|FYN_BOVIN Tyrosine-protein kinase Fyn OS=Bos taurus
OX=9913 GN=FYN PE=2 SV=1
Length=537
Score = 144 bits (362), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 91/277 (33%), Positives = 139/277 (50%), Gaps = 29/277 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ I+ LG G FG+V + ++ VA+K LK G + +E I++ L H
Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAIKTLKP--GTMSPESFLEEAQIMKKLKH 323
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013
+ +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY
Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 380
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ +YIHRDL + N+L+ N + KI DFGLA+ + + Y R+ P+ W APE
Sbjct 381 IERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+F SDVWSFG+ L EL+T + M + E +ERG R
Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+P P CP ++ LM +CW+ + RPTFE L L+
Sbjct 485 MPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLE 521
Score = 77.4 bits (189), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 65/230 (28%), Positives = 102/230 (44%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L
Sbjct 295 KVAIKTLKPGTMSPE-SFLEEAQIMKKLKHDKLVQLYAVVSEEPIYI-VTEYMNKGSLLD 352
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G K
Sbjct 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GNGLICK 405
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
P + E +R +R+P P CP L L C +P +RP+F
Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 513
>sp|Q16832|DDR2_HUMAN Discoidin domain-containing receptor 2 OS=Homo
sapiens OX=9606 GN=DDR2 PE=1 SV=2
Length=855
Score = 147 bits (370), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 96/298 (32%), Positives = 143/298 (48%), Gaps = 34/298 (11%)
Query 892 FHKRYLKKIRDLGEGHFGKVSL-------------YCYDPTNDGTGEMVAVKALKADCGP 938
F ++ L LGEG FG+V L + D + + +VAVK L+AD
Sbjct 558 FPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN-QPVLVAVKMLRADANK 616
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----- 993
R+ + +EI I+ L +II C + L ++ EY+ G L +L RH
Sbjct 617 NARNDFLKEIKIMSRLKDPNIIHLLAVC--ITDDPLCMITEYMENGDLNQFLSRHEPPNS 674
Query 994 ------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
++ L A QI GM YL + +++HRDLA RN L+ + +KI DFG+++
Sbjct 675 SSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRN 734
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ G +YYR++ P+ W + E + KF ASDVW+FGVTL+E T C Q P
Sbjct 735 LYSG-DYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC---QEQPYS 790
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L + + R R LP+P CP VY LM +CW + RP+F+ +
Sbjct 791 QLSDEQVIENTGEFFRDQ---GRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEI 845
Score = 72.0 bits (175), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 71/255 (28%), Positives = 113/255 (44%), Gaps = 35/255 (14%)
Query 634 GQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
Q + V +K+L + A F + +MS++ ++ + VC+ M+TEY+E+
Sbjct 600 NQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMEN 659
Query 693 GPLDVWLRR---------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
G L+ +L R + V +A Q+AS + YL + N VH ++ RN L+
Sbjct 660 GDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLV- 718
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDK 797
G + IK++D G+ S + V I W++ E + G +TA D
Sbjct 719 ------GKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLG--KFTTASDV 770
Query 798 WGFGATLLE-ICFDGEAPLQSRSPSE----KEHFYQ---RQHRLPEPS-CPQ-LATLTSQ 847
W FG TL E F E P S + F++ RQ LP+P+ CP + L
Sbjct 771 WAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLS 830
Query 848 CLTYEPTQRPSFRTI 862
C + RPSF+ I
Sbjct 831 CWRRDTKNRPSFQEI 845
>sp|P31693|SRC_RSVPA Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus (strain PA101T) OX=31667 GN=V-SRC
PE=3 SV=3
Length=523
Score = 143 bits (361), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 100/301 (33%), Positives = 151/301 (50%), Gaps = 34/301 (11%)
Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
H L +V T P + A D + L+ LG+G+FG+V + ++ T VA
Sbjct 236 HRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGYFGEVWMGTWNGTT-----RVA 290
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL D
Sbjct 291 IKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAMV---SEEPIYIVIEYMSKGSLLD 345
Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 346 FL-KGEMGKYLRLPQLVEMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 404
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R PV W APE +F SDVWSFG+ L EL T
Sbjct 405 ARLIEDNE--YTARPGARFPVKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 457
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ G+ G+ + + +ERG R+P P +CP ++ LM CW + RPTFE
Sbjct 458 ----VPYPGMVNGE-----VLDRVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEY 508
Query 1165 L 1165
L
Sbjct 509 L 509
Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 67/231 (29%), Positives = 107/231 (46%), Gaps = 21/231 (9%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ + P I++ EY+ G L
Sbjct 288 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAMVSEEPIYIVI-EYMSKGSLLD 345
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 346 FLKGEMGKYLRLPQLVEMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 398
Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
++D G+ + E R + W APE G ++ + D W FG L E+
Sbjct 399 VADFGLAR-LIEDNEYTARPGARFPVKWTAPEAALYGRFTIKS--DVWSFGILLTELTTK 455
Query 811 GEAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859
G P E +R +R+P P CP+ L L QC +P +RP+F
Sbjct 456 GRVPYPGMVNGEVLDRVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTF 506
>sp|O18735|ERBB2_CANLF Receptor tyrosine-protein kinase erbB-2
OS=Canis lupus familiaris OX=9615 GN=ERBB2 PE=2 SV=1
Length=1259
Score = 147 bits (372), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 89/278 (32%), Positives = 140/278 (50%), Gaps = 20/278 (7%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+ + L+K++ LG G FG V + P + VA+K L+ + P+ E +
Sbjct 713 ILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYV 772
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQIC 1008
+ + ++ + G C ++QLV + +P G L D++ H +G LL + QI
Sbjct 773 MAGVGSPYVSRLLGICL---TSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIA 829
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+GM+YL +HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W
Sbjct 830 KGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWM 888
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A E + +F + SDVWS+GVT++EL+T + + +LL
Sbjct 889 ALESIPPRRFTHQSDVWSYGVTVWELMT--------------FGAKPYDGIPAREIPDLL 934
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
E+GERLP+P C +VY +M CW ++ RP F L+
Sbjct 935 EKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELV 972
Score = 68.6 bits (166), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 84/366 (23%), Positives = 148/366 (40%), Gaps = 50/366 (14%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+Q + + E+ ++ LG G VY+G +G E+ +P
Sbjct 707 NQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDG-----------ENVKIP------- 748
Query 637 LRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +KVL + A + A +M+ V +++ + G+C+ +VT+ + +G L
Sbjct 749 --VAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQLMPYGCL 805
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R RG + + Q+A +SYLE+ LVH ++ RN+L+ + +
Sbjct 806 LDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVK-------SPNHV 858
Query 756 KLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
K++D GL L + E I W+A E +P + D W +G T+ E+
Sbjct 859 KITD--FGLARLLDIDETEYHADGGKVPIKWMALESIP--PRRFTHQSDVWSYGVTVWEL 914
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRD 865
G P E ++ RLP+P + + +C + RP FR ++ +
Sbjct 915 MTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVAE 974
Query 866 LTRLQPHNLADVLTVNPD-SPASDPTVFHKRYLKKIRDLG------EGHFGKVSLYCYDP 918
+R+ V+ N D PAS R L + D+G E + +C +P
Sbjct 975 FSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPEP 1034
Query 919 TNDGTG 924
T G
Sbjct 1035 TPGAGG 1040
>sp|P29318|EPHA3_CHICK Ephrin type-A receptor 3 OS=Gallus gallus
OX=9031 GN=EPHA3 PE=1 SV=1
Length=983
Score = 147 bits (371), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 87/270 (32%), Positives = 141/270 (52%), Gaps = 21/270 (8%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG+V S P+ VA+K LKA + R + E I+ H +II+
Sbjct 627 VGAGEFGEVCSGRLKLPSKKEIS--VAIKTLKAGYTEKQRRDFLGEASIMGQFDHPNIIR 684
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHY 1019
+G K + +V EY+ GSL +L +H + QL+ + I GM YL Y
Sbjct 685 LEGVVTKS--KPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGY 742
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W +PE + KF
Sbjct 743 VHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFT 802
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
ASD WS+G+ L+E++++ + P +M+ + + ++ G RLP P
Sbjct 803 SASDAWSYGIVLWEVMSY---GERP-----------YWEMSFQDVIKAVDEGYRLPPPMD 848
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
CP +Y LM +CW+ + + RP FE ++ IL
Sbjct 849 CPAALYQLMLDCWQKDRNNRPKFEQIVSIL 878
Score = 86.7 bits (213), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 68/245 (28%), Positives = 110/245 (45%), Gaps = 19/245 (8%)
Query 635 QELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+E+ V +K L + + F AS+M Q H ++ + GV + ++VTEY+E+G
Sbjct 646 KEISVAIKTLKAGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENG 705
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
LD +LR+ + + + + +AS + YL + VH ++ RNIL+ ++
Sbjct 706 SLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILI-------NSNL 758
Query 754 FIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLE 806
K+SD G+ E R +IP W +PE + ++A D W +G L E
Sbjct 759 VCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAI--AYRKFTSASDAWSYGIVLWE 816
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILR 864
+ GE P S + +RLP P CP L L C + RP F I+
Sbjct 817 VMSYGERPYWEMSFQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVS 876
Query 865 DLTRL 869
L +L
Sbjct 877 ILDKL 881
>sp|Q1JPZ3|SRC_DANRE Proto-oncogene tyrosine-protein kinase Src
OS=Danio rerio OX=7955 GN=src PE=1 SV=2
Length=534
Score = 143 bits (361), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 101/306 (33%), Positives = 151/306 (49%), Gaps = 34/306 (11%)
Query 872 HNLADVLTV-NPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
H+L DV V P + A D + L+ LG+G FG+V + ++ T VA
Sbjct 240 HSLTDVCPVLKPPTQGLARDAWEIPRDSLRLDVKLGQGCFGEVWMGTWNGTT-----RVA 294
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL D
Sbjct 295 IKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS---EEPIYIVTEYMGQGSLLD 349
Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ ++ + K+ DFGL
Sbjct 350 FL-KGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGL 408
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 409 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 461
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW E RPTFE
Sbjct 462 ---------VPYPGMVNREVLDQVERGYRMPCPAECPDSLHELMLTCWRKEPEERPTFEY 512
Query 1165 LIPILK 1170
L L+
Sbjct 513 LQGFLE 518
Score = 79.3 bits (194), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 69/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L
Sbjct 292 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMGQGSLLD 349
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ + G + ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 350 FLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILV-------GDNLVCK 402
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 403 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 460
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSF 859
P E +R +R+P P+ CP L L C EP +RP+F
Sbjct 461 RVPYPGMVNREVLDQVERGYRMPCPAECPDSLHELMLTCWRKEPEERPTF 510
>sp|Q26614|FGFR_STRPU Fibroblast growth factor receptor OS=Strongylocentrotus
purpuratus OX=7668 GN=FGFR PE=2 SV=1
Length=972
Score = 147 bits (370), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 99/304 (33%), Positives = 150/304 (49%), Gaps = 45/304 (15%)
Query 892 FHKRYLKKIRDLGEGHFGKV------SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
F + L + +GEG FGKV + C + T+ VAVK LKA+ + S
Sbjct 634 FPRDRLTVGKTIGEGAFGKVVIGEAVGIVCQEKTS-----TVAVKMLKANAMDREFSDLI 688
Query 946 QEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------------- 990
E+ +++ + + +II GCC +G +++E+ G+LRD+L
Sbjct 689 SELAMMKMIGKNPNIINLLGCCTQEGPP--YVIVEFAHHGNLRDFLRSRRPPEEYEKSIL 746
Query 991 --PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
++ L+ A Q+ GM +L ++ IHRDLAARNVL+ D +KI DFGLA+ +
Sbjct 747 LTTSQTLTNKDLMSMAYQVARGMDFLASKKCIHRDLAARNVLVTEDFEMKICDFGLARDI 806
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
++YR DG PV W APE L + F SDVWSFG+ L+E++T
Sbjct 807 -HYIDFYRKTTDGRLPVKWMAPEALFDRMFTTQSDVWSFGILLWEIMT------------ 853
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
L G + V ++ + L G+RL +P E+YH++ CW T RPTF L+
Sbjct 854 --LGGTPYPSVPVEQMFDYLRSGKRLEKPQNTSLEIYHILCECWRTSPGQRPTFCELVED 911
Query 1169 LKTV 1172
L +
Sbjct 912 LDRI 915
Score = 60.1 bits (144), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 60/221 (27%), Positives = 94/221 (43%), Gaps = 39/221 (18%)
Query 675 GVCVR-GPENIMVTEYVEHGPLDVWLRRERGHVPMAWK----------------MVVAQQ 717
G C + GP ++V E+ HG L +LR R P ++ M +A Q
Sbjct 708 GCCTQEGPPYVIV-EFAHHGNLRDFLRSRRP--PEEYEKSILLTTSQTLTNKDLMSMAYQ 764
Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF-IKLSDPGVGLGA----LSREER 772
+A + +L +K +H ++ RN+L+ T F +K+ D G+ R+
Sbjct 765 VARGMDFLASKKCIHRDLAARNVLV--------TEDFEMKICDFGLARDIHYIDFYRKTT 816
Query 773 VERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
R+P W+APE L +T D W FG L EI G P S + + +
Sbjct 817 DGRLPVKWMAPEAL--FDRMFTTQSDVWSFGILLWEIMTLGGTPYPSVPVEQMFDYLRSG 874
Query 831 HRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869
RL +P L + +C P QRP+F ++ DL R+
Sbjct 875 KRLEKPQNTSLEIYHILCECWRTSPGQRPTFCELVEDLDRI 915
>sp|P51813|BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX OS=Homo
sapiens OX=9606 GN=BMX PE=1 SV=1
Length=675
Score = 145 bits (366), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 93/278 (33%), Positives = 139/278 (50%), Gaps = 27/278 (10%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+++LG G FG V L + D VAVK +K G + QE + L H +
Sbjct 420 LKELGSGQFGVVQLGKWKGQYD-----VAVKMIKE--GSMSEDEFFQEAQTMMKLSHPKL 472
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQ 1017
+K+ G C E + +V EY+ G L +YL H GL +QLL +CEGMA+L +
Sbjct 473 VKFYGVCSK--EYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESH 530
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+IHRDLAARN L+D D VK+ DFG+ + V + Y PV W APE +K
Sbjct 531 QFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQ--YVSSVGTKFPVKWSAPEVFHYFK 588
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ SDVW+FG+ ++E+ + + P + VL++++ G RL RP
Sbjct 589 YSSKSDVWAFGILMWEVFS---LGKQP-------YDLYDNSQVVLKVSQ----GHRLYRP 634
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+Y +M +CW RPTF+ L+ ++ + EK
Sbjct 635 HLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLREK 672
Score = 65.5 bits (158), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 54/224 (24%), Positives = 98/224 (44%), Gaps = 18/224 (8%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F++ A M ++SH L +GVC + +VTEY+ +G L +LR + + + +
Sbjct 457 FFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEM 516
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ +++LE+ +H ++ RN L+ R +K+SD G+ L ++ V
Sbjct 517 CYDVCEGMAFLESHQFIHRDLAARNCLVDR-------DLCVKVSDFGMTRYVLD-DQYVS 568
Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
+ W APE S+ D W FG + E+ G+ P S+
Sbjct 569 SVGTKFPVKWSAPEVF--HYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVS 626
Query 829 RQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ HRL P + + + C P +RP+F+ +L + L+
Sbjct 627 QGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLR 670
>sp|Q05688|IGF1R_BOVIN Insulin-like growth factor 1 receptor (Fragment)
OS=Bos taurus OX=9913 GN=IGF1R PE=2 SV=1
Length=640
Score = 144 bits (364), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 95/286 (33%), Positives = 144/286 (50%), Gaps = 29/286 (10%)
Query 901 RDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
R+LG+G FG V D VA+K + + R + E +++ H+
Sbjct 276 RELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHV 335
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIG-------LAQLLLFAQQIC 1008
++ G QG+ +L ++ME + G L+ YL P L++++ A +I
Sbjct 336 VRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIA 393
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+GMAYL+A ++HRDLAARN ++ D VKIGDFG+ + + E +YYR G PV W
Sbjct 394 DGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYE-TDYYRKGGKGLLPVRWM 452
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
+PE LK+ F SDVWSFGV L+E+ T + G++ Q VLR +
Sbjct 453 SPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQ---------GLSNEQ--VLR---FV 498
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
G L +PD CP ++ LM+ CW+ RP+F +I +K E
Sbjct 499 MEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSVKDEME 544
Score = 84.0 bits (206), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 79/301 (26%), Positives = 127/301 (42%), Gaps = 46/301 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +++IT LGQG+ VYEG + G + DE E RV +K
Sbjct 267 VAREKITMSRELGQGSFGMVYEGVAK---------GVVKDE----------PETRVAIKT 307
Query 644 LD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
++ + + F AS+M + + H+ + GV +G +++ E + G L +LR
Sbjct 308 VNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSL 367
Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
R + P KM+ +A ++A ++YL VH ++ RN ++A
Sbjct 368 RPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAE-------DF 420
Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+ D G+ + + + + W++PE L G +T D W FG L EI
Sbjct 421 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTHSDVWSFGVVLWEI 478
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRD 865
E P Q S + F L +P +CP L L C Y P RPSF I+
Sbjct 479 ATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISS 538
Query 866 L 866
+
Sbjct 539 V 539
>sp|P06494|ERBB2_RAT Receptor tyrosine-protein kinase erbB-2 OS=Rattus
norvegicus OX=10116 GN=Erbb2 PE=1 SV=3
Length=1257
Score = 147 bits (371), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 89/278 (32%), Positives = 140/278 (50%), Gaps = 20/278 (7%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+ + L+K++ LG G FG V + P + VA+K L+ + P+ E +
Sbjct 716 ILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYV 775
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQIC 1008
+ + ++ + G C ++QLV + +P G L D++ H +G LL + QI
Sbjct 776 MAGVGSPYVSRLLGICL---TSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIA 832
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+GM+YL +HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W
Sbjct 833 KGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWM 891
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A E + +F + SDVWS+GVT++EL+T + + +LL
Sbjct 892 ALESILRRRFTHQSDVWSYGVTVWELMT--------------FGAKPYDGIPAREIPDLL 937
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
E+GERLP+P C +VY +M CW ++ RP F L+
Sbjct 938 EKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELV 975
Score = 64.3 bits (155), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 77/342 (23%), Positives = 142/342 (42%), Gaps = 46/342 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+Q + + E+ ++ LG G VY+G +G E+ +P
Sbjct 710 NQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDG-----------ENVKIP------- 751
Query 637 LRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +KVL + A + A +M+ V +++ + G+C+ +VT+ + +G L
Sbjct 752 --VAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQLMPYGCL 808
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R RG + + Q+A +SYLE+ LVH ++ RN+L+ + +
Sbjct 809 LDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVK-------SPNHV 861
Query 756 KLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
K++D GL L + E I W+A E + + D W +G T+ E+
Sbjct 862 KITD--FGLARLLDIDETEYHADGGKVPIKWMALESI--LRRRFTHQSDVWSYGVTVWEL 917
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRD 865
G P E ++ RLP+P + + +C + RP FR ++ +
Sbjct 918 MTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSE 977
Query 866 LTRLQPHNLADVLTVNPDSPASDP--TVFHKRYLKKIRDLGE 905
+R+ V+ N D S P + F++ L+ D+G+
Sbjct 978 FSRMARDPQRFVVIQNEDLGPSSPMDSTFYRSLLED-DDMGD 1018
>sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src
OS=Homo sapiens OX=9606 GN=SRC PE=1 SV=3
Length=536
Score = 143 bits (360), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 91/271 (34%), Positives = 136/271 (50%), Gaps = 29/271 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++
Sbjct 276 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQL 328
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHY 1019
E+ + +V EY+ GSL D+L + + L QL+ A QI GMAY+ +Y
Sbjct 329 YAVVS---EEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNY 385
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F
Sbjct 386 VHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFT 443
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SDVWSFG+ L EL T + M + + +ERG R+P P +
Sbjct 444 IKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPPE 489
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
CP ++ LM CW E RPTFE L L+
Sbjct 490 CPESLHDLMCQCWRKEPEERPTFEYLQAFLE 520
Score = 83.6 bits (205), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 71/230 (31%), Positives = 106/230 (46%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L
Sbjct 294 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 351
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 352 FLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 404
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 405 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 462
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859
P E +R +R+P P CP+ L L QC EP +RP+F
Sbjct 463 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTF 512
>sp|O13148|EPA4A_DANRE Ephrin type-A receptor 4a (Fragment) OS=Danio
rerio OX=7955 GN=epha4a PE=2 SV=1
Length=292
Score = 137 bits (345), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 79/254 (31%), Positives = 132/254 (52%), Gaps = 27/254 (11%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VA+K LKA + R + E I+ H +II+ +G K + ++ EY+ GSL
Sbjct 24 VAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIRLEGVVTKC--KPVMIITEYMENGSL 81
Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L ++ + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFG+
Sbjct 82 DAFLRKNDGRFTVIQLVGILRGIASGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGM 141
Query 1045 AKAVPEGHE-YYRVRE--------DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
++ + E + Y RE G P+ W APE + KF ASDVWS+G+ ++E++
Sbjct 142 SRVLEEDPDAAYTTREITGTYQSQGGKIPIRWTAPEAITYRKFTSASDVWSYGIVMWEVM 201
Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155
++ + M+ + + +E G RLP P CP ++ LM +CW+ E
Sbjct 202 SYGER--------------PYWDMSNQDVIKAIEEGYRLPPPMDCPVSLHQLMLDCWQKE 247
Query 1156 ASFRPTFENLIPIL 1169
+ RP F ++ +L
Sbjct 248 RAERPKFSQIVNML 261
Score = 93.2 bits (230), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 76/276 (28%), Positives = 125/276 (45%), Gaps = 40/276 (14%)
Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+PG+ +E+ V +K L + D F AS+M Q H ++ + GV + +++
Sbjct 16 MPGK---REICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIRLEGVVTKCKPVMII 72
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TEY+E+G LD +LR+ G + + + + +AS + YL + + VH ++ RNIL+
Sbjct 73 TEYMENGSLDAFLRKNDGRFTVIQLVGILRGIASGMKYLSDMSYVHRDLAARNILV---- 128
Query 747 LAEGTSPFIKLSDPGVG--------LGALSRE------ERVERIP--WLAPECLPGGANS 790
++ K+SD G+ +RE + +IP W APE +
Sbjct 129 ---NSNLVCKVSDFGMSRVLEEDPDAAYTTREITGTYQSQGGKIPIRWTAPEAIT--YRK 183
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQC 848
++A D W +G + E+ GE P S + + +RLP P CP L L C
Sbjct 184 FTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPVSLHQLMLDC 243
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884
E +RP F I+ N+ D L NP+S
Sbjct 244 WQKERAERPKFSQIV---------NMLDKLIRNPNS 270
>sp|Q25410|MIPR_LYMST Putative molluscan insulin-related peptide(s)
receptor OS=Lymnaea stagnalis OX=6523 PE=2 SV=1
Length=1607
Score = 147 bits (371), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 107/350 (31%), Positives = 169/350 (48%), Gaps = 42/350 (12%)
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901
+L C+ Y+ R T++ P +++L + SD + +K I+
Sbjct 991 VSLIVACVYYKQKIRSDDMTVISRNMNYVP---SEILYI------SDEWEVDRDKIKLIK 1041
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEM--VAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+LG+G FG V D E VAVK + R + +E ++ + H+
Sbjct 1042 ELGQGSFGMVYEGVAKGIRDDPNEEIPVAVKTVNDRASFSDRREFLKEATTMKEFHCHHV 1101
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----------LAQLLLFAQQICE 1009
+K G G+ +L ++ME + LG L++YL H L +L A +I +
Sbjct 1102 VKLLGVVS-TGQPAL-VIMELMALGDLKNYLRGHRPDEDHPGVMPPHLLDILQMAGEIAD 1159
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
GMAYL + ++HRDLAARN ++ +R VKIGDFG+ + + E +YYR G PV W A
Sbjct 1160 GMAYLADKKFVHRDLAARNCMVSEERTVKIGDFGMTRDIYET-DYYRKGGKGMLPVRWMA 1218
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE LK+ F SDVWS+GV ++E++T L ++ + + +
Sbjct 1219 PESLKDGVFTSLSDVWSYGVVMWEMVT--------------LAAQPYQGLSNEEVVKFIS 1264
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTF----ENLIPILKTVHEK 1175
G + P+ CP E+ +LM++CW + + RPTF E L+P LK EK
Sbjct 1265 DGYIMELPENCPNEMAYLMQHCWAKKPNQRPTFKAIIEYLLPKLKPSFEK 1314
Score = 79.3 bits (194), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 79/306 (26%), Positives = 134/306 (44%), Gaps = 45/306 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
VD+ +I + LGQG+ VYEG + G DD + +P V V
Sbjct 1032 VDRDKIKLIKELGQGSFGMVYEGVAK---------GIRDDPNEEIP--------VAVKTV 1074
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
D + F + A+ M + H+ + GV G +++ E + G L +LR R
Sbjct 1075 NDRASFSDRREFLKEATTMKEFHCHHVVKLLGVVSTGQPALVIMELMALGDLKNYLRGHR 1134
Query 704 ------GHVP--MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
G +P + + +A ++A ++YL +K VH ++ RN +++ E T +
Sbjct 1135 PDEDHPGVMPPHLLDILQMAGEIADGMAYLADKKFVHRDLAARNCMVSE----ERT---V 1187
Query 756 KLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
K+ D G+ + + + + W+APE L G ++ D W +G + E+
Sbjct 1188 KIGDFGMTRDIYETDYYRKGGKGMLPVRWMAPESLKDGV--FTSLSDVWSYGVVMWEMVT 1245
Query 810 DGEAPLQSRSPSEKEHFYQRQH--RLPEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDL 866
P Q S E F + LPE +CP ++A L C +P QRP+F+ I+ L
Sbjct 1246 LAAQPYQGLSNEEVVKFISDGYIMELPE-NCPNEMAYLMQHCWAKKPNQRPTFKAIIEYL 1304
Query 867 T-RLQP 871
+L+P
Sbjct 1305 LPKLKP 1310
>sp|P03949|ABL1_CAEEL Tyrosine-protein kinase abl-1 OS=Caenorhabditis
elegans OX=6239 GN=abl-1 PE=1 SV=4
Length=1224
Score = 147 bits (371), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 99/266 (37%), Positives = 136/266 (51%), Gaps = 27/266 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G +G V Y +D T +AVKALK D P H + E I++ L+H+++++
Sbjct 317 LGGGQYGDV-YEGYWKRHDCT---IAVKALKEDAMPLHE--FLAEAAIMKDLHHKNLVRL 370
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLHAQHY 1019
G C E ++ E++ G+L +YL R L L+ A QI GM+YL A+H+
Sbjct 371 LGVC--THEAPFYIITEFMCNGNLLEYLRRTDKSLLPPIILVQMASQIASGMSYLEARHF 428
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRDLAARN L+ +VKI DFGLA+ + E + Y P+ W APE L F
Sbjct 429 IHRDLAARNCLVSEHNIVKIADFGLARFMKE--DTYTAHAGAKFPIKWTAPEGLAFNTFS 486
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SDVW+FGV L+E+ T+ P +EL + LLE G R+ P
Sbjct 487 SKSDVWAFGVLLWEIATYG----MAPYPGVELSNVYG----------LLENGFRMDGPQG 532
Query 1140 CPCEVYHLMKNCWETEASFRPTFENL 1165
CP VY LM CW S RP F ++
Sbjct 533 CPPSVYRLMLQCWNWSPSDRPRFRDI 558
Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 81/300 (27%), Positives = 129/300 (43%), Gaps = 46/300 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+D+ EI + LG G +VYEG + + +D PL
Sbjct 306 LDRSEIIMHNKLGGGQYGDVYEGYWKRHDCTIAVKALKEDAMPL---------------- 349
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702
H+ F A++M + H +L + GVC ++TE++ +G L +LRR +
Sbjct 350 -----HE----FLAEAAIMKDLHHKNLVRLLGVCTHEAPFYIITEFMCNGNLLEYLRRTD 400
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ +P + +A Q+AS +SYLE ++ +H ++ RN L++ + +K++D
Sbjct 401 KSLLPPIILVQMASQIASGMSYLEARHFIHRDLAARNCLVSEHNI-------VKIAD--F 451
Query 763 GLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
GL +E+ I W APE L N+ S+ D W FG L EI G AP
Sbjct 452 GLARFMKEDTYTAHAGAKFPIKWTAPEGL--AFNTFSSKSDVWAFGVLLWEIATYGMAPY 509
Query 816 QSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
S + R+ P+ P + L QC + P+ RP FR I +L L N
Sbjct 510 PGVELSNVYGLLENGFRMDGPQGCPPSVYRLMLQCWNWSPSDRPRFRDIHFNLENLISSN 569
>sp|Q09YK0|MET_MUNMU Hepatocyte growth factor receptor OS=Muntiacus
muntjak OX=9888 GN=MET PE=3 SV=1
Length=1382
Score = 147 bits (371), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 144/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T ND AVK+L S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLASK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ V + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1305 QPEYCPDALYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348
Score = 60.8 bits (146), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1184 GFGLQVAKGMEYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDVYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1295 VYLLQGRRLLQPEYCPDALYEVMLKCWHPKAELRPSFSELVSRISAI 1341
>sp|Q6EWH2|FYNA_DANRE Tyrosine-protein kinase fyna OS=Danio rerio
OX=7955 GN=fyna PE=1 SV=2
Length=537
Score = 143 bits (360), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 91/277 (33%), Positives = 137/277 (49%), Gaps = 29/277 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ I+ LG G FG+V + ++ VAVK LK G + +E I++ L H
Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAVKTLKP--GTMSPESFLEEAQIMKKLRH 323
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013
+ +++ E+ + +V EY+ GSL D+L + L L+ A Q+ GMAY
Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMSKGSLLDFLKDGEGRGLKLPNLVDMAAQVAAGMAY 380
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ +YIHRDL + N+L+ + + KI DFGLA+ + + Y R+ P+ W APE
Sbjct 381 IERMNYIHRDLRSANILVGDSLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+F SDVWSFG+ L EL+T + M + E +ERG R
Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+P P CP ++ LM CW+ + RPTFE L L+
Sbjct 485 MPCPQDCPSSLHELMLQCWKRDPEERPTFEYLQAFLE 521
Score = 77.8 bits (190), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 67/230 (29%), Positives = 104/230 (45%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L
Sbjct 295 KVAVKTLKPGTMSPE-SFLEEAQIMKKLRHDKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 352
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G S K
Sbjct 353 FLKDGEGRGLKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GDSLVCK 405
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
P + E +R +R+P P CP L L QC +P +RP+F
Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPSSLHELMLQCWKRDPEERPTF 513
>sp|Q2IBC0|MET_RHIFE Hepatocyte growth factor receptor OS=Rhinolophus
ferrumequinum OX=59479 GN=MET PE=3 SV=1
Length=1381
Score = 147 bits (370), Expect = 3e-34, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T ND AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD + VK+ DFGLA+ V + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDENFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDHLYEVMLKCWHPKAEQRPSFAELVSRISAIFSAFIGE 1347
Score = 64.7 bits (156), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 56/227 (25%), Positives = 102/227 (45%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L + +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------NFTVKVADFGLARDVYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + QRPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDHLYEVMLKCWHPKAEQRPSFAELVSRISAI 1340
>sp|P04626|ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2
OS=Homo sapiens OX=9606 GN=ERBB2 PE=1 SV=1
Length=1255
Score = 147 bits (370), Expect = 3e-34, Method: Compositional matrix adjust.
Identities = 89/278 (32%), Positives = 140/278 (50%), Gaps = 20/278 (7%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+ + L+K++ LG G FG V + P + VA+K L+ + P+ E +
Sbjct 714 ILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYV 773
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQIC 1008
+ + ++ + G C ++QLV + +P G L D++ R +G LL + QI
Sbjct 774 MAGVGSPYVSRLLGICL---TSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIA 830
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+GM+YL +HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W
Sbjct 831 KGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWM 889
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A E + +F + SDVWS+GVT++EL+T + + +LL
Sbjct 890 ALESILRRRFTHQSDVWSYGVTVWELMT--------------FGAKPYDGIPAREIPDLL 935
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
E+GERLP+P C +VY +M CW ++ RP F L+
Sbjct 936 EKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELV 973
Score = 67.0 bits (162), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 86/369 (23%), Positives = 149/369 (40%), Gaps = 51/369 (14%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+Q + + E+ ++ LG G VY+G +G E+ +P
Sbjct 708 NQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDG-----------ENVKIP------- 749
Query 637 LRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +KVL + A + A +M+ V +++ + G+C+ +VT+ + +G L
Sbjct 750 --VAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQLMPYGCL 806
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R RG + + Q+A +SYLE+ LVH ++ RN+L+ + +
Sbjct 807 LDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVK-------SPNHV 859
Query 756 KLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
K++D GL L + E I W+A E + + D W +G T+ E+
Sbjct 860 KITD--FGLARLLDIDETEYHADGGKVPIKWMALESI--LRRRFTHQSDVWSYGVTVWEL 915
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRD 865
G P E ++ RLP+P + + +C + RP FR ++ +
Sbjct 916 MTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSE 975
Query 866 LTRLQPHNLADVLTVNPD-SPASDPTVFHKRYLKKIRDLG------EGHFGKVSLYCYDP 918
+R+ V+ N D PAS R L + D+G E + +C DP
Sbjct 976 FSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDP 1035
Query 919 TNDGTGEMV 927
G G MV
Sbjct 1036 A-PGAGGMV 1043
>sp|P51451|BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo sapiens
OX=9606 GN=BLK PE=1 SV=3
Length=505
Score = 142 bits (358), Expect = 3e-34, Method: Compositional matrix adjust.
Identities = 96/303 (32%), Positives = 146/303 (48%), Gaps = 32/303 (11%)
Query 882 PDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH 940
P +P A D ++ L+ +R LG G FG+V + Y VA+K LK G
Sbjct 225 PQNPWAQDEWEIPRQSLRLVRKLGSGQFGEVWMGYYK-----NNMKVAIKTLKE--GTMS 277
Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGL 997
+ E ++++ L HE +++ + + +V EY+ G L D+L + L
Sbjct 278 PEAFLGEANVMKALQHERLVRLYAVVTKE---PIYIVTEYMARGCLLDFLKTDEGSRLSL 334
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+L+ + QI EGMAY+ + IHRDL A N+L+ KI DFGLA+ + Y
Sbjct 335 PRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARII---DSEYTA 391
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
+E P+ W APE + F +DVWSFGV L E++T+ +
Sbjct 392 QEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGR--------------VPYP 437
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYH-LMKNCWETEASFRPTFENLIPILKTVHEKY 1176
M+ + LERG R+PRPD CP E+Y ++ CW + RPTFE L +L+ +
Sbjct 438 GMSNPEVIRNLERGYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEFLQSVLEDFYTAT 497
Query 1177 QGQ 1179
+ Q
Sbjct 498 ERQ 500
Score = 73.9 bits (180), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 60/226 (27%), Positives = 106/226 (47%), Gaps = 25/226 (11%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKM 712
AF A++M + H L ++ V + P I VTEY+ G L +L+ + G + + +
Sbjct 280 AFLGEANVMKALQHERLVRLYAVVTKEPIYI-VTEYMARGCLLDFLKTDEGSRLSLPRLI 338
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
++ Q+A ++Y+E N +H ++ NIL++ + K++D GL + E
Sbjct 339 DMSAQIAEGMAYIERMNSIHRDLRAANILVSE-------ALCCKIAD--FGLARIIDSEY 389
Query 773 VER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ I W APE + G ++ D W FG L+E+ G P S E
Sbjct 390 TAQEGAKFPIKWTAPEAIHFGVFTIKA--DVWSFGVLLMEVVTYGRVPYPGMSNPEVIRN 447
Query 827 YQRQHRLPEP-SCPQ--LATLTSQCLTYEPTQRPSF---RTILRDL 866
+R +R+P P +CP + ++C P +RP+F +++L D
Sbjct 448 LERGYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEFLQSVLEDF 493
>sp|A1X150|MET_ECHTE Hepatocyte growth factor receptor OS=Echinops
telfairi OX=9371 GN=MET PE=3 SV=1
Length=1380
Score = 147 bits (370), Expect = 3e-34, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 144/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T ND AVK+L S + E I++ H ++
Sbjct 1083 IGRGHFGCV----YHGTLLDNDDRKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1138
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ HS + L+ F Q+ +GM YL ++
Sbjct 1139 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHSPTVKDLIGFGLQVAKGMKYLASK 1197
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1198 KFVHRDLAARNCMLDGKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1256
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1257 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1302
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1303 QPEYCPDPLYEVMLKCWHPKAEMRPSFTELVSRISAIFSTFIGE 1346
Score = 62.0 bits (149), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 56/227 (25%), Positives = 102/227 (45%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1123 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HSPTVKDLI 1181
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +G +K++D G+ +E
Sbjct 1182 GFGLQVAKGMKYLASKKFVHRDLAARNCML------DGKFT-VKVADFGLARDMYDKEYY 1234
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1235 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1292
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1293 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFTELVSRISAI 1339
>sp|Q769I5|MET_BOVIN Hepatocyte growth factor receptor OS=Bos
taurus OX=9913 GN=MET PE=2 SV=1
Length=1384
Score = 147 bits (370), Expect = 3e-34, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 144/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T ND AVK+L S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLASK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ V + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISVIFSTFIGE 1348
Score = 60.8 bits (146), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1184 GFGLQVAKGMEYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDVYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISVI 1341
>sp|F1RDG9|FYNB_DANRE Tyrosine-protein kinase fynb OS=Danio rerio
OX=7955 GN=fynb PE=2 SV=1
Length=544
Score = 142 bits (359), Expect = 3e-34, Method: Compositional matrix adjust.
Identities = 91/277 (33%), Positives = 138/277 (50%), Gaps = 29/277 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ I+ LG G FG+V + ++ VA+K LK G + +E I++ L H
Sbjct 278 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAIKTLKP--GTMSPESFLEEAQIMKKLRH 330
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013
+ +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY
Sbjct 331 DKLVQLYAVVS---EEPIYIVTEYMGKGSLLDFLKDGEGRALKLPNLVDMAAQVAGGMAY 387
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ +YIHRDL + N+L+ + + KI DFGLA+ + + Y R+ P+ W APE
Sbjct 388 IERMNYIHRDLRSANILVGDSLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 445
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
KF SDVWSFG+ L EL+T + M + E +ERG R
Sbjct 446 LYGKFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 491
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ P CP ++ LM CW+ +A RPTFE L L+
Sbjct 492 MQCPQDCPSSLHELMVQCWKKDAEERPTFEYLQAFLE 528
Score = 73.2 bits (178), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 65/230 (28%), Positives = 101/230 (44%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L
Sbjct 302 KVAIKTLKPGTMSPE-SFLEEAQIMKKLRHDKLVQLYAVVSEEPIYI-VTEYMGKGSLLD 359
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G +V +A Q+A ++Y+E N +H ++ NIL+ G S K
Sbjct 360 FLKDGEGRALKLPNLVDMAAQVAGGMAYIERMNYIHRDLRSANILV-------GDSLVCK 412
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 413 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGKFTIKS--DVWSFGILLTELVTKG 470
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
P + E +R +R+ P CP L L QC + +RP+F
Sbjct 471 RVPYPGMNNREVLEQVERGYRMQCPQDCPSSLHELMVQCWKKDAEERPTF 520
>sp|P70424|ERBB2_MOUSE Receptor tyrosine-protein kinase erbB-2
OS=Mus musculus OX=10090 GN=Erbb2 PE=1 SV=3
Length=1256
Score = 146 bits (369), Expect = 3e-34, Method: Compositional matrix adjust.
Identities = 89/278 (32%), Positives = 140/278 (50%), Gaps = 20/278 (7%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+ + L+K++ LG G FG V + P + VA+K L+ + P+ E +
Sbjct 715 ILKETELRKLKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYV 774
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQIC 1008
+ + ++ + G C ++QLV + +P G L D++ H +G LL + QI
Sbjct 775 MAGVGSPYVSRLLGICL---TSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIA 831
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+GM+YL +HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W
Sbjct 832 KGMSYLEEVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWM 890
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A E + +F + SDVWS+GVT++EL+T + + +LL
Sbjct 891 ALESILRRRFTHQSDVWSYGVTVWELMT--------------FGAKPYDGIPAREIPDLL 936
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
E+GERLP+P C +VY +M CW ++ RP F L+
Sbjct 937 EKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELV 974
Score = 65.9 bits (159), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 79/342 (23%), Positives = 141/342 (41%), Gaps = 46/342 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+Q + + E+ +L LG G VY+G +G E+ +P
Sbjct 709 NQAQMRILKETELRKLKVLGSGAFGTVYKGIWIPDG-----------ENVKIP------- 750
Query 637 LRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +KVL + A + A +M+ V +++ + G+C+ +VT+ + +G L
Sbjct 751 --VAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQLMPYGCL 807
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R RG + + Q+A +SYLE LVH ++ RN+L+ + +
Sbjct 808 LDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVRLVHRDLAARNVLVK-------SPNHV 860
Query 756 KLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
K++D GL L + E I W+A E + + D W +G T+ E+
Sbjct 861 KITD--FGLARLLDIDETEYHADGGKVPIKWMALESI--LRRRFTHQSDVWSYGVTVWEL 916
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRD 865
G P E ++ RLP+P + + +C + RP FR ++ +
Sbjct 917 MTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSE 976
Query 866 LTRLQPHNLADVLTVNPDSPASDP--TVFHKRYLKKIRDLGE 905
+R+ V+ N D S P + F++ L+ D+GE
Sbjct 977 FSRMARDPQRFVVIQNEDLGPSSPMDSTFYRSLLED-DDMGE 1017
>sp|P63185|SRC_RSVSE Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus subgroup E (strain Schmidt-Ruppin)
OX=270623 GN=V-SRC PE=1 SV=3
Length=526
Score = 142 bits (358), Expect = 3e-34, Method: Compositional matrix adjust.
Identities = 98/301 (33%), Positives = 151/301 (50%), Gaps = 34/301 (11%)
Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
H L +V T P + A D + L+ LG+G FG+V + ++ T VA
Sbjct 239 HRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTT-----RVA 293
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK G + QE +++ L H+ +++ E+ + +V+EY+ GSL D
Sbjct 294 IKTLKP--GTMSPEAFLQEAQVMKKLRHKKLVQLYAVVS---EEPIYIVIEYMSKGSLLD 348
Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 349 FL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ G+ G+ + + +ERG R+P P +CP ++ LM CW + RPTFE
Sbjct 461 ----VPYPGMGNGE-----VLDRVERGYRMPCPPECPESLHDLMSQCWRRDPEERPTFEY 511
Query 1165 L 1165
L
Sbjct 512 L 512
Score = 83.2 bits (204), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 70/237 (30%), Positives = 109/237 (46%), Gaps = 19/237 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I++ EY+ G L
Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHKKLVQLYAVVSEEPIYIVI-EYMSKGSLLD 348
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866
P E +R +R+P P CP+ L L SQC +P +RP+F + L
Sbjct 460 RVPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMSQCWRRDPEERPTFEYLQAQL 516
>sp|P29320|EPHA3_HUMAN Ephrin type-A receptor 3 OS=Homo sapiens
OX=9606 GN=EPHA3 PE=1 SV=2
Length=983
Score = 146 bits (368), Expect = 3e-34, Method: Compositional matrix adjust.
Identities = 87/270 (32%), Positives = 141/270 (52%), Gaps = 21/270 (8%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG+V S P+ VA+K LK + R + E I+ H +II+
Sbjct 627 VGAGEFGEVCSGRLKLPSKKEIS--VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIR 684
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHY 1019
+G K + +V EY+ GSL +L +H + QL+ + I GM YL Y
Sbjct 685 LEGVVTKS--KPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGY 742
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W +PE + KF
Sbjct 743 VHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFT 802
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
ASDVWS+G+ L+E++++ + P +M+ + + ++ G RLP P
Sbjct 803 SASDVWSYGIVLWEVMSY---GERP-----------YWEMSNQDVIKAVDEGYRLPPPMD 848
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
CP +Y LM +CW+ + + RP FE ++ IL
Sbjct 849 CPAALYQLMLDCWQKDRNNRPKFEQIVSIL 878
Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 68/245 (28%), Positives = 110/245 (45%), Gaps = 19/245 (8%)
Query 635 QELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+E+ V +K L + + F AS+M Q H ++ + GV + ++VTEY+E+G
Sbjct 646 KEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENG 705
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
LD +LR+ + + + + +AS + YL + VH ++ RNIL+ ++
Sbjct 706 SLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILI-------NSNL 758
Query 754 FIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLE 806
K+SD G+ E R +IP W +PE + ++A D W +G L E
Sbjct 759 VCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAI--AYRKFTSASDVWSYGIVLWE 816
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILR 864
+ GE P S + +RLP P CP L L C + RP F I+
Sbjct 817 VMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVS 876
Query 865 DLTRL 869
L +L
Sbjct 877 ILDKL 881
>sp|P00524|SRC_RSVSA Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus subgroup A (strain Schmidt-Ruppin)
OX=269446 GN=V-SRC PE=1 SV=6
Length=526
Score = 142 bits (358), Expect = 4e-34, Method: Compositional matrix adjust.
Identities = 99/301 (33%), Positives = 151/301 (50%), Gaps = 34/301 (11%)
Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
H L +V T P + A D + L+ LG+G FG+V + ++ T VA
Sbjct 239 HRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTT-----RVA 293
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL D
Sbjct 294 IKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS---EEPIYIVIEYMSKGSLLD 348
Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 349 FL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ G+ G+ + + +ERG R+P P +CP ++ LM CW + RPTFE
Sbjct 461 ----VPYPGMGNGE-----VLDRVERGYRMPCPPECPESLHDLMCQCWRRDPEERPTFEY 511
Query 1165 L 1165
L
Sbjct 512 L 512
Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 69/237 (29%), Positives = 108/237 (46%), Gaps = 19/237 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I++ EY+ G L
Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVI-EYMSKGSLLD 348
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866
P E +R +R+P P CP+ L L QC +P +RP+F + L
Sbjct 460 RVPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMCQCWRRDPEERPTFEYLQAQL 516
>sp|Q09YI9|MET_SHEEP Hepatocyte growth factor receptor OS=Ovis
aries OX=9940 GN=MET PE=3 SV=1
Length=1384
Score = 146 bits (369), Expect = 4e-34, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 144/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T ND AVK+L S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLASK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS--PVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ V + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRIAAIFSAFIGE 1348
Score = 60.8 bits (146), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 99/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1184 GFGLQVAKGMEYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDVYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ + +
Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRIAAI 1341
>sp|Q00PJ8|MET_ATEAB Hepatocyte growth factor receptor OS=Atelerix
albiventris OX=9368 GN=MET PE=3 SV=1
Length=1382
Score = 146 bits (369), Expect = 4e-34, Method: Compositional matrix adjust.
Identities = 96/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T ND AVK+L S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD + VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDENFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348
Score = 61.2 bits (147), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 101/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L + +K++D G+ +E
Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------NFTVKVADFGLARDMYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1341
>sp|Q8AXY6|MUSK_CHICK Muscle, skeletal receptor tyrosine protein
kinase OS=Gallus gallus OX=9031 GN=MUSK PE=2 SV=1
Length=947
Score = 145 bits (367), Expect = 4e-34, Method: Compositional matrix adjust.
Identities = 93/313 (30%), Positives = 156/313 (50%), Gaps = 51/313 (16%)
Query 892 FHKRYLKKIRDLGEGHFGKV------SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
+ + ++ +RD+GEG FG+V L Y+P MVAVK LK + ++ ++
Sbjct 650 YPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFT-----MVAVKMLKEEASADMQADFQ 704
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ-- 999
+E ++ + +I+K G C K + L+ EY+ G L +YL PR+ L Q
Sbjct 705 REAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEYLRDRSPRNLCSLVQGG 762
Query 1000 -----------------LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
L A+Q+ GMAYL + ++HRDLA RN L+ + +VKI DF
Sbjct 763 LEARACLLNPLALCCTSQLCIAKQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADF 822
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
GL++ + +YY+ E+ P+ W PE + ++ SDVW++GV L+E+ ++
Sbjct 823 GLSRNMYSA-DYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSY----- 876
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
G+A ++ + G L PD CP E+Y+LM+ CW + RP+F
Sbjct 877 ----GMQPYYGMAHEEVIY-----YVRDGNILSCPDNCPLELYNLMRLCWSKLPADRPSF 927
Query 1163 ENLIPILKTVHEK 1175
++ IL+ ++E+
Sbjct 928 ASIHRILERMYER 940
Score = 77.4 bits (189), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 69/268 (26%), Positives = 120/268 (45%), Gaps = 39/268 (15%)
Query 639 VVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V +K+L + + D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+
Sbjct 686 VAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNE 745
Query 698 WLR-----------------RERGHVPMAW----KMVVAQQLASALSYLENKNLVHGNVC 736
+LR R P+A ++ +A+Q+A+ ++YL + VH ++
Sbjct 746 YLRDRSPRNLCSLVQGGLEARACLLNPLALCCTSQLCIAKQVAAGMAYLSERKFVHRDLA 805
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANS 790
RN L+ G + +K++D G+ S E I W+ PE + N
Sbjct 806 TRNCLV-------GENMVVKIADFGLSRNMYSADYYKANENDAIPIRWMPPESI--FYNR 856
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQC 848
+T D W +G L EI G P + E ++ + + L P +CP +L L C
Sbjct 857 YTTESDVWAYGVVLWEIFSYGMQPYYGMAHEEVIYYVRDGNILSCPDNCPLELYNLMRLC 916
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLAD 876
+ P RPSF +I R L R+ +A
Sbjct 917 WSKLPADRPSFASIHRILERMYERAVAS 944
>sp|O08680|EPHA3_RAT Ephrin type-A receptor 3 OS=Rattus norvegicus
OX=10116 GN=Epha3 PE=2 SV=1
Length=984
Score = 145 bits (367), Expect = 5e-34, Method: Compositional matrix adjust.
Identities = 88/270 (33%), Positives = 140/270 (52%), Gaps = 21/270 (8%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG+V S P+ VA+K LK + R + E I+ H +II+
Sbjct 628 VGAGEFGEVCSGRLKLPSKKEIS--VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIR 685
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHY 1019
+G K + +V EY+ GSL +L +H + QL+ + I GM YL Y
Sbjct 686 LEGVVTKS--KPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGY 743
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDLAARN+L++++ + K+ DFGL++ + + E G PV W +PE KF
Sbjct 744 VHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPVRWTSPEATAYRKFT 803
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
ASDVWS+G+ L+E++++ + P +M+ + + ++ G RLP P
Sbjct 804 SASDVWSYGIVLWEVMSY---GERP-----------YWEMSNQDVIKAVDEGYRLPLPMD 849
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
CP +Y LM +CW+ + + RP FE ++ IL
Sbjct 850 CPAALYQLMLDCWQKDRNNRPKFEQIVSIL 879
Score = 84.7 bits (208), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 68/245 (28%), Positives = 109/245 (44%), Gaps = 19/245 (8%)
Query 635 QELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+E+ V +K L + + F AS+M Q H ++ + GV + ++VTEY+E+G
Sbjct 647 KEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENG 706
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
LD +LR+ + + + + +AS + YL + VH ++ RNIL+ ++
Sbjct 707 SLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILI-------NSNL 759
Query 754 FIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLE 806
K+SD G+ E R +IP W +PE ++A D W +G L E
Sbjct 760 VCKVSDFGLSRVLEDDPEAAYTTRGGKIPVRWTSPEAT--AYRKFTSASDVWSYGIVLWE 817
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILR 864
+ GE P S + +RLP P CP L L C + RP F I+
Sbjct 818 VMSYGERPYWEMSNQDVIKAVDEGYRLPLPMDCPAALYQLMLDCWQKDRNNRPKFEQIVS 877
Query 865 DLTRL 869
L +L
Sbjct 878 ILDKL 882
>sp|Q2QLE0|MET_PIG Hepatocyte growth factor receptor OS=Sus scrofa
OX=9823 GN=MET PE=2 SV=1
Length=1381
Score = 146 bits (368), Expect = 5e-34, Method: Compositional matrix adjust.
Identities = 97/284 (34%), Positives = 143/284 (50%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T ND AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ V + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGE 1347
Score = 60.5 bits (145), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 99/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDVYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAI 1340
>sp|Q9WUD9|SRC_RAT Proto-oncogene tyrosine-protein kinase Src
OS=Rattus norvegicus OX=10116 GN=Src PE=1 SV=4
Length=536
Score = 142 bits (357), Expect = 5e-34, Method: Compositional matrix adjust.
Identities = 90/271 (33%), Positives = 136/271 (50%), Gaps = 29/271 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++
Sbjct 276 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQL 328
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHY 1019
E+ + +V EY+ GSL D+L + + L QL+ + QI GMAY+ +Y
Sbjct 329 YAVV---SEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNY 385
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F
Sbjct 386 VHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFT 443
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SDVWSFG+ L EL T + M + + +ERG R+P P +
Sbjct 444 IKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPPE 489
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
CP ++ LM CW E RPTFE L L+
Sbjct 490 CPESLHDLMCQCWRKEPEERPTFEYLQAFLE 520
Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L
Sbjct 294 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMNKGSLLD 351
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V ++ Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 352 FLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 404
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 405 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 462
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859
P E +R +R+P P CP+ L L QC EP +RP+F
Sbjct 463 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTF 512
>sp|P05480|SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src
OS=Mus musculus OX=10090 GN=Src PE=1 SV=5
Length=535
Score = 142 bits (357), Expect = 5e-34, Method: Compositional matrix adjust.
Identities = 90/271 (33%), Positives = 136/271 (50%), Gaps = 29/271 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++
Sbjct 275 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQL 327
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHY 1019
E+ + +V EY+ GSL D+L + + L QL+ + QI GMAY+ +Y
Sbjct 328 YAVV---SEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNY 384
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F
Sbjct 385 VHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFT 442
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SDVWSFG+ L EL T + M + + +ERG R+P P +
Sbjct 443 IKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPPE 488
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
CP ++ LM CW E RPTFE L L+
Sbjct 489 CPESLHDLMCQCWRKEPEERPTFEYLQAFLE 519
Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L
Sbjct 293 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMNKGSLLD 350
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V ++ Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 351 FLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 403
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 404 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 461
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859
P E +R +R+P P CP+ L L QC EP +RP+F
Sbjct 462 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTF 511
>sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens
OX=9606 GN=ABL2 PE=1 SV=1
Length=1182
Score = 145 bits (367), Expect = 5e-34, Method: Compositional matrix adjust.
Identities = 94/287 (33%), Positives = 145/287 (51%), Gaps = 27/287 (9%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
TV SP D + + LG G +G+V + + + VAVK LK D
Sbjct 270 TVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYS----LTVAVKTLKEDT-- 323
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSI 995
+ +E +++ + H ++++ G C E +V EY+P G+L DYL R +
Sbjct 324 MEVEEFLKEAAVMKEIKHPNLVQLLGVC--TLEPPFYIVTEYMPYGNLLDYLRECNREEV 381
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
LL A QI M YL +++IHRDLAARN L+ + +VK+ DFGL++ + + Y
Sbjct 382 TAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDTY 439
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
P+ W APE L F SDVW+FGV L+E+ T+ S P ++L
Sbjct 440 TAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMS----PYPGIDLS--- 492
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
++ +LLE+G R+ +P+ CP +VY LM+ CW+ + RP+F
Sbjct 493 -------QVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSF 532
Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 70/231 (30%), Positives = 109/231 (47%), Gaps = 18/231 (8%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
L V +K L ++ F + A++M ++ H +L + GVC P +VTEY+ +G L
Sbjct 312 LTVAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLL 370
Query 697 VWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+LR R V + +A Q++SA+ YLE KN +H ++ RN L+ G + +
Sbjct 371 DYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV-------GENHVV 423
Query 756 KLSDPGVG---LGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ G + P W APE L N+ S D W FG L EI
Sbjct 424 KVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESL--AYNTFSIKSDVWAFGVLLWEIATY 481
Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859
G +P S+ ++ +R+ PE P++ L C + P RPSF
Sbjct 482 GMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSF 532
>sp|P54756|EPHA5_HUMAN Ephrin type-A receptor 5 OS=Homo sapiens
OX=9606 GN=EPHA5 PE=1 SV=3
Length=1037
Score = 145 bits (366), Expect = 6e-34, Method: Compositional matrix adjust.
Identities = 89/273 (33%), Positives = 142/273 (52%), Gaps = 23/273 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
R +G G FG+V C G E+ VA+K LK + R + E I+ H +
Sbjct 679 RVIGAGEFGEV---CSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPN 735
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHA 1016
II +G K + +V EY+ GSL +L ++ + QL+ + I GM YL
Sbjct 736 IIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSD 793
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W APE +
Sbjct 794 MGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFR 853
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
KF ASDVWS+G+ ++E++++ + P +MT + + +E G RLP
Sbjct 854 KFTSASDVWSYGIVMWEVVSY---GERP-----------YWEMTNQDVIKAVEEGYRLPS 899
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P CP +Y LM +CW+ E + RP F+ ++ +L
Sbjct 900 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNML 932
Score = 90.1 bits (222), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 79/286 (28%), Positives = 129/286 (45%), Gaps = 33/286 (12%)
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSH 667
RV G+G E G++ +PG+ +EL V +K L + + F AS+M Q H
Sbjct 679 RVIGAG--EFGEVCSGRLKLPGK---RELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDH 733
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
++ + GV + ++VTEY+E+G LD +L++ G + + + + +++ + YL +
Sbjct 734 PNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSD 793
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIP--WLA 780
VH ++ RNIL+ ++ K+SD G+ E R +IP W A
Sbjct 794 MGYVHRDLAARNILI-------NSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTA 846
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP 839
PE + ++A D W +G + E+ GE P + + + +RLP P CP
Sbjct 847 PEAI--AFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCP 904
Query 840 -QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884
L L C E RP F I+ N+ D L NP S
Sbjct 905 AALYQLMLDCWQKERNSRPKFDEIV---------NMLDKLIRNPSS 941
>sp|P54755|EPHA5_CHICK Ephrin type-A receptor 5 OS=Gallus gallus
OX=9031 GN=EPHA5 PE=2 SV=1
Length=1013
Score = 145 bits (366), Expect = 6e-34, Method: Compositional matrix adjust.
Identities = 88/273 (32%), Positives = 141/273 (52%), Gaps = 23/273 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
R +G G FG+V C G E VA+K LK + R + E I+ H +
Sbjct 655 RVIGAGEFGEV---CSGRLKLQGKREFPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPN 711
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHA 1016
II +G K + +V EY+ GSL +L ++ + QL+ + I GM YL
Sbjct 712 IIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIASGMKYLSD 769
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W APE +
Sbjct 770 MGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFR 829
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
KF ASDVWS+G+ ++E++++ + P +MT + + +E G RLP
Sbjct 830 KFTSASDVWSYGIVMWEVMSY---GERP-----------YWEMTNQDVIKAVEEGYRLPS 875
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P CP +Y LM +CW+ + + RP F+ ++ +L
Sbjct 876 PMDCPAALYQLMLDCWQKDRNSRPKFDEIVSML 908
Score = 90.5 bits (223), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 84/317 (26%), Positives = 135/317 (43%), Gaps = 44/317 (14%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
IT +G G V GRL+++G +E V +K L +
Sbjct 651 ITIERVIGAGEFGEVCSGRLKLQGK---------------------REFPVAIKTLKVGY 689
Query 649 HDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
+ F AS+M Q H ++ + GV + ++VTEY+E+G LD +L++ G
Sbjct 690 TEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFT 749
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
+ + + + +AS + YL + VH ++ RNIL+ ++ K+SD G+
Sbjct 750 VIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILI-------NSNLVCKVSDFGLSRVLE 802
Query 768 SREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
E R +IP W APE + ++A D W +G + E+ GE P +
Sbjct 803 DDPEAAYTTRGGKIPIRWTAPEAI--AFRKFTSASDVWSYGIVMWEVMSYGERPYWEMTN 860
Query 821 SEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLAD 876
+ + +RLP P CP L L C + RP F I+ L +L P +L
Sbjct 861 QDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVSMLDKLIRNPSSLKT 920
Query 877 VLTVNPDSPASDPTVFH 893
+ VN S S+ V H
Sbjct 921 L--VNASSRVSNLLVEH 935
>sp|P42682|TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus musculus
OX=10090 GN=Txk PE=1 SV=1
Length=527
Score = 141 bits (356), Expect = 6e-34, Method: Compositional matrix adjust.
Identities = 98/292 (34%), Positives = 140/292 (48%), Gaps = 47/292 (16%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-----VAVKALKADCGPQHRSGWKQEIDIL 951
L ++++G G FG V L GE VA+KA+ G + +E ++
Sbjct 271 LAFVKEIGSGQFGVVHL----------GEWRAHIPVAIKAINE--GSMSEEDFIEEAKVM 318
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICE 1009
L H +++ G C Q K L +V E++ G L DYL L + LL + Q ICE
Sbjct 319 MKLSHSRLVQLYGVCIQQ--KPLYIVTEFMENGCLLDYLRERKGQLQKALLLSMCQDICE 376
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
GMAYL YIHRDLAARN L+ + +VKI DFG+A+ V + Y PV W
Sbjct 377 GMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARYVLDDE--YISSSGAKFPVKWCP 434
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM-----TVLRL 1124
PE K+ SDVWSFGV ++E+ T +G+M + L++
Sbjct 435 PEVFHFNKYSSKSDVWSFGVLMWEVFT-------------------EGKMPFENKSNLQV 475
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
E + +G RL RP P +Y +M +CW RPTF L+ +L + E +
Sbjct 476 VEAISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVLTEIAETW 527
Score = 89.0 bits (219), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 58/222 (26%), Positives = 105/222 (47%), Gaps = 16/222 (7%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F E A +M ++SH+ L ++GVC++ +VTE++E+G L +LR +G + A + +
Sbjct 311 FIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRERKGQLQKALLLSM 370
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
Q + ++YLE +H ++ RN L++ ++ +K+SD G+ L E
Sbjct 371 CQDICEGMAYLERSCYIHRDLAARNCLVS-------SACVVKISDFGMARYVLDDEYISS 423
Query 775 R-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
+ W PE N S+ D W FG + E+ +G+ P +++S + +
Sbjct 424 SGAKFPVKWCPPEVF--HFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISQ 481
Query 830 QHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869
RL P + + C P RP+F +L+ LT +
Sbjct 482 GFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVLTEI 523
>sp|P14084|SRC_AVISS Tyrosine-protein kinase transforming protein
Src OS=Avian sarcoma virus (strain S1) OX=11881 GN=V-SRC
PE=3 SV=3
Length=568
Score = 142 bits (358), Expect = 6e-34, Method: Compositional matrix adjust.
Identities = 91/272 (33%), Positives = 137/272 (50%), Gaps = 31/272 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++
Sbjct 273 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVRL 325
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLHAQH 1018
E+ + +V EY+ GSL D+L + +G L QL+ A QI GMAY+ +
Sbjct 326 YAVV---SEEPIYIVTEYMSKGSLLDFL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMN 381
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
Y+HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F
Sbjct 382 YVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRF 439
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SDVWSFG+ L EL T + M + + +ERG R+P P
Sbjct 440 TIKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPP 485
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+CP ++ LM CW + RPTFE L L+
Sbjct 486 ECPESLHDLMCQCWRKDPEERPTFEYLQAFLE 517
Score = 82.0 bits (201), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L
Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVRLYAVVSEEPIYI-VTEYMSKGSLLD 348
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859
P E +R +R+P P CP+ L L QC +P +RP+F
Sbjct 460 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTF 509
>sp|P00526|SRC_RSVP Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus subgroup C (strain Prague) OX=11888
GN=V-SRC PE=1 SV=3
Length=526
Score = 141 bits (356), Expect = 7e-34, Method: Compositional matrix adjust.
Identities = 98/301 (33%), Positives = 149/301 (50%), Gaps = 34/301 (11%)
Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
H LA+V T P + A D + L+ LG+G FG+V + ++ T VA
Sbjct 239 HRLANVCPTSKPQTQGLAKDAWEIPRESLRLEAKLGQGCFGEVWMGTWNDTT-----RVA 293
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL D
Sbjct 294 IKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVIEYMSKGSLLD 348
Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 349 FL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW + RPTF+
Sbjct 461 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFKY 511
Query 1165 L 1165
L
Sbjct 512 L 512
Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 69/237 (29%), Positives = 109/237 (46%), Gaps = 19/237 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I++ EY+ G L
Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVI-EYMSKGSLLD 348
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866
P E +R +R+P P CP+ L L QC +P +RP+F+ + L
Sbjct 460 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFKYLQAQL 516
>sp|P27447|YES_XIPHE Tyrosine-protein kinase Yes OS=Xiphophorus
hellerii OX=8084 GN=yes PE=2 SV=3
Length=544
Score = 141 bits (356), Expect = 7e-34, Method: Compositional matrix adjust.
Identities = 88/271 (32%), Positives = 138/271 (51%), Gaps = 29/271 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+V + ++ T VA+K LK G + +E I++ L H+ ++
Sbjct 284 LGQGCFGEVWMGTWNGTTK-----VAIKTLKP--GTMSPEAFLEEAQIMKKLRHDKLVPL 336
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHY 1019
E+ + +V E++ GSL D+L + L QL+ A QI +GMA++ +Y
Sbjct 337 YAVVS---EEPIYIVTEFMGKGSLLDFLKEGDGKHLKLPQLVDMASQIADGMAFIERMNY 393
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRDL A N+L+ ++ + KI DFGLA+ + + Y R+ P+ W APE +F
Sbjct 394 IHRDLRAANILVADNLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFT 451
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SDVWSFG+ L EL+T + M + E ++RG R+P P
Sbjct 452 IKSDVWSFGILLTELVTKGR--------------VPYPGMVNREVLEQVDRGYRMPCPQG 497
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
CP ++ +M+ CW+ E RPTFE + L+
Sbjct 498 CPESLHEMMRQCWKKEPDERPTFEYIQSFLE 528
Score = 78.6 bits (192), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 66/233 (28%), Positives = 105/233 (45%), Gaps = 19/233 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P AF E A +M ++ H L ++ V P I VTE++ G L
Sbjct 302 KVAIKTLKPGTMSPE-AFLEEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEFMGKGSLLD 359
Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G H+ + + +A Q+A ++++E N +H ++ NIL+A + K
Sbjct 360 FLKEGDGKHLKLPQLVDMASQIADGMAFIERMNYIHRDLRAANILVA-------DNLVCK 412
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 413 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 470
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
P E R +R+P P CP+ L + QC EP +RP+F I
Sbjct 471 RVPYPGMVNREVLEQVDRGYRMPCPQGCPESLHEMMRQCWKKEPDERPTFEYI 523
>sp|P00525|SRC_AVISR Tyrosine-protein kinase transforming protein
Src OS=Avian sarcoma virus (strain rASV1441) OX=11894 GN=V-SRC
PE=1 SV=3
Length=526
Score = 141 bits (356), Expect = 7e-34, Method: Compositional matrix adjust.
Identities = 99/301 (33%), Positives = 150/301 (50%), Gaps = 34/301 (11%)
Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
H L +V T P + A D + L+ LG+G FG+V + ++ T VA
Sbjct 239 HRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTT-----RVA 293
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL D
Sbjct 294 IKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS---EEPIYIVTEYMSKGSLLD 348
Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 349 FL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ G+ G+ + + +ERG R+P P +CP ++ LM CW + RPTFE
Sbjct 461 ----VPYPGMGNGE-----VLDRVERGYRMPCPPECPESLHDLMCQCWRRDPEERPTFEY 511
Query 1165 L 1165
L
Sbjct 512 L 512
Score = 82.8 bits (203), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L
Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 348
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859
P E +R +R+P P CP+ L L QC +P +RP+F
Sbjct 460 RVPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMCQCWRRDPEERPTF 509
>sp|Q8MY85|FGFR2_DUGJA Fibroblast growth factor receptor 2 OS=Dugesia
japonica OX=6161 GN=FGFR2 PE=2 SV=1
Length=887
Score = 144 bits (364), Expect = 7e-34, Method: Compositional matrix adjust.
Identities = 120/365 (33%), Positives = 170/365 (47%), Gaps = 54/365 (15%)
Query 837 SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896
S + LTS LT E TQRP IL++ N +L P++ +F +
Sbjct 539 SNTETNKLTSNSLTVE-TQRPQL--ILQN-----DANTKYIL------PSNIGWIFSRDS 584
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTL- 954
L +GEG FG V ++ + + VA+K L G Q QE+++++ +
Sbjct 585 LIIGSKIGEGAFGIVYSALVKSFSENSASVEVAIKTLHTSFGDQDVINLIQELEMMKIIG 644
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------PRHSIGLA----- 998
H HII G C D G +V+E G+LRD+L ++S GL
Sbjct 645 RHRHIISLYGACIDNGHP--YMVIELAKHGNLRDFLRAQRSQSKVGEIQNSGGLVTRLTV 702
Query 999 -QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
L F+ +I EGM YL ++ IHRDLAARNVL+D +KI DFGL + V YYR
Sbjct 703 TDFLRFSIEIAEGMEYLSSRKIIHRDLAARNVLVDQYVEMKIADFGLTRIV---ENYYRK 759
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQ 1116
DG P+ W APECL + + SDVWS+G+ L+E+ T Q+P PT ++ G+ Q
Sbjct 760 TTDGRLPIKWMAPECLLDRVYTVKSDVWSYGIVLWEIFTM---GQTPYPT--IQSDGMHQ 814
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
L G R +P E+Y LM W + R TF +I L +
Sbjct 815 A----------LRNGIRNEKPALASDEMYRLMLTIWNDDPLERHTFSEIIDKLTHIQLSN 864
Query 1177 QGQAP 1181
G +P
Sbjct 865 GGSSP 869
Score = 64.3 bits (155), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 54/231 (23%), Positives = 101/231 (44%), Gaps = 36/231 (16%)
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-----GHVPMAWKMVV------- 714
H H+ ++G C+ MV E +HG L +LR +R G + + +V
Sbjct 646 HRHIISLYGACIDNGHPYMVIELAKHGNLRDFLRAQRSQSKVGEIQNSGGLVTRLTVTDF 705
Query 715 ---AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--- 768
+ ++A + YL ++ ++H ++ RN+L+ + ++++ GL +
Sbjct 706 LRFSIEIAEGMEYLSSRKIIHRDLAARNVLVDQ---------YVEMKIADFGLTRIVENY 756
Query 769 -REERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP---LQSRSPSE 822
R+ R+P W+APECL ++ + D W +G L EI G+ P +QS +
Sbjct 757 YRKTTDGRLPIKWMAPECLLDRVYTVKS--DVWSYGIVLWEIFTMGQTPYPTIQSDGMHQ 814
Query 823 KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
R + P + ++ L +P +R +F I+ LT +Q N
Sbjct 815 ALRNGIRNEK-PALASDEMYRLMLTIWNDDPLERHTFSEIIDKLTHIQLSN 864
>sp|P13115|SRC1_XENLA Tyrosine-protein kinase Src-1 OS=Xenopus
laevis OX=8355 GN=src-a PE=2 SV=4
Length=532
Score = 141 bits (356), Expect = 7e-34, Method: Compositional matrix adjust.
Identities = 91/272 (33%), Positives = 136/272 (50%), Gaps = 31/272 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++
Sbjct 272 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQL 324
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLHAQH 1018
E+ + +V EY+ GSL D+L + +G L QL+ A QI GMAY+ +
Sbjct 325 YAVVS---EEPIYIVTEYISKGSLLDFL-KGEMGRYLRLPQLVDMAAQIASGMAYVERMN 380
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
Y+HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F
Sbjct 381 YVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRF 438
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SDVWSFG+ L EL T + M + + +ERG R+P P
Sbjct 439 TIKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPP 484
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
CP ++ LM CW + RPTFE L L+
Sbjct 485 DCPESLHDLMFQCWRKDPEERPTFEYLQAFLE 516
Score = 83.2 bits (204), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L
Sbjct 290 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYISKGSLLD 347
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 348 FLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 400
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 401 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 458
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859
P E +R +R+P P CP+ L L QC +P +RP+F
Sbjct 459 RVPYPGMVNREVLDQVERGYRMPCPPDCPESLHDLMFQCWRKDPEERPTF 508
>sp|Q2QLA9|MET_HORSE Hepatocyte growth factor receptor OS=Equus
caballus OX=9796 GN=MET PE=3 SV=1
Length=1381
Score = 145 bits (366), Expect = 8e-34, Method: Compositional matrix adjust.
Identities = 96/284 (34%), Positives = 144/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T ND AVK+L S + E I++ H ++
Sbjct 1084 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1347
Score = 60.8 bits (146), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1340
>sp|Q07E24|MET_MUSPF Hepatocyte growth factor receptor OS=Mustela
putorius furo OX=9669 GN=MET PE=3 SV=1
Length=1382
Score = 145 bits (366), Expect = 8e-34, Method: Compositional matrix adjust.
Identities = 96/284 (34%), Positives = 144/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T ND AVK+L S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348
Score = 60.8 bits (146), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1341
>sp|Q8MY86|FGFR1_DUGJA Fibroblast growth factor receptor 1 OS=Dugesia
japonica OX=6161 GN=FGFR1 PE=2 SV=1
Length=854
Score = 144 bits (364), Expect = 8e-34, Method: Compositional matrix adjust.
Identities = 94/295 (32%), Positives = 150/295 (51%), Gaps = 37/295 (13%)
Query 901 RDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEH 958
+ LGEG FG V D N VAVK ++ D + + +E++I++ + H +
Sbjct 555 KKLGEGAFGMVYEGIANDIGNRSNPIKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPN 614
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------------SIGLAQLLLFAQQ 1006
+I+ G C +G L++++E P G+LRD++ + + L ++ Q
Sbjct 615 VIQLLGLCTQKG--PLRVIVELAPYGNLRDFVRAKNKKYSKSKKIIGNFTSSILCTYSLQ 672
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I GM YL ++ +HRDL+ARN+L+ +KI DFGL + V YYR + DG PV
Sbjct 673 IARGMTYLASRSVVHRDLSARNILVGEHFEMKIADFGLTRIVDY---YYRKKTDGILPVK 729
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLELIGIAQGQMTVLRL 1124
W APE L E K+ SDVWS+G+ L+E+ T DS S P K ++LI
Sbjct 730 WMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDSPYSAILPEKVVDLI------------ 777
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+G + P+P+ E+Y LM++CW + RP F ++ IL + ++ +
Sbjct 778 ----RKGFQNPKPELANFEIYRLMQHCWSLSSENRPNFFEIVEILIDIIQRIDDE 828
Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 67/299 (22%), Positives = 129/299 (43%), Gaps = 49/299 (16%)
Query 632 DRGQELRVVLKVL-----DPSHHDIALAFYETASLMSQVS-HTHLAFVHGVCV-RGPENI 684
+R ++V +K++ D + HD F + +M + H ++ + G+C +GP +
Sbjct 575 NRSNPIKVAVKMMRDDFSDSNVHD----FVKEMEIMKHIGRHPNVIQLLGLCTQKGPLRV 630
Query 685 MVTEYVEHGPLDVWLRRER----------GHVPMAWKMVVAQQLASALSYLENKNLVHGN 734
+V E +G L ++R + G+ + + Q+A ++YL ++++VH +
Sbjct 631 IV-ELAPYGNLRDFVRAKNKKYSKSKKIIGNFTSSILCTYSLQIARGMTYLASRSVVHRD 689
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANS 790
+ RNIL+ G +K++D G V + + + + W+APE L
Sbjct 690 LSARNILV-------GEHFEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALL--EKK 740
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP--QLATLTSQC 848
+T D W +G L EI G++P + P + ++ + P+P ++ L C
Sbjct 741 YTTKSDVWSYGILLWEIFTLGDSPYSAILPEKVVDLIRKGFQNPKPELANFEIYRLMQHC 800
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK--RYLKKIRDLGE 905
+ RP+F I+ L D++ D P + ++H YLK D E
Sbjct 801 WSLSSENRPNFFEIVEILI--------DIIQRIDDEP--EENIYHSELNYLKMESDYLE 849
>sp|P29319|EPHA3_MOUSE Ephrin type-A receptor 3 OS=Mus musculus
OX=10090 GN=Epha3 PE=1 SV=1
Length=983
Score = 145 bits (365), Expect = 8e-34, Method: Compositional matrix adjust.
Identities = 87/270 (32%), Positives = 139/270 (51%), Gaps = 21/270 (8%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG+V S P+ VA+K LK + R + E I+ H +II+
Sbjct 627 VGAGEFGEVCSGRLKLPSKKEIS--VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIR 684
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHY 1019
+G K +V EY+ GSL +L +H + QL+ + I GM YL Y
Sbjct 685 LEGVVTKS--KPEMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGY 742
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W +PE + KF
Sbjct 743 VHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAMSYRKFT 802
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
ASDVWS+G+ L+E++++ + S QM+ + + ++ RLP P
Sbjct 803 SASDVWSYGIVLWEVMSYGERPYS--------------QMSNQDVIKAVDERYRLPPPMD 848
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
CP +Y LM +CW+ + + RP FE ++ IL
Sbjct 849 CPAALYQLMLDCWQKDRNNRPKFEQIVSIL 878
Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 68/245 (28%), Positives = 111/245 (45%), Gaps = 19/245 (8%)
Query 635 QELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+E+ V +K L + + F AS+M Q H ++ + GV + ++VTEY+E+G
Sbjct 646 KEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPEMIVTEYMENG 705
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
LD +LR+ + + + + +AS + YL + VH ++ RNIL+ ++
Sbjct 706 SLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILI-------NSNL 758
Query 754 FIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLE 806
K+SD G+ E R +IP W +PE + ++A D W +G L E
Sbjct 759 VCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAM--SYRKFTSASDVWSYGIVLWE 816
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILR 864
+ GE P S + ++RLP P CP L L C + RP F I+
Sbjct 817 VMSYGERPYSQMSNQDVIKAVDERYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVS 876
Query 865 DLTRL 869
L +L
Sbjct 877 ILDKL 881
>sp|P00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src
OS=Gallus gallus OX=9031 GN=SRC PE=1 SV=4
Length=533
Score = 141 bits (355), Expect = 8e-34, Method: Compositional matrix adjust.
Identities = 91/272 (33%), Positives = 137/272 (50%), Gaps = 31/272 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++
Sbjct 273 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQL 325
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLHAQH 1018
E+ + +V EY+ GSL D+L + +G L QL+ A QI GMAY+ +
Sbjct 326 YAVV---SEEPIYIVTEYMSKGSLLDFL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMN 381
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
Y+HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F
Sbjct 382 YVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRF 439
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SDVWSFG+ L EL T + M + + +ERG R+P P
Sbjct 440 TIKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPP 485
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+CP ++ LM CW + RPTFE L L+
Sbjct 486 ECPESLHDLMCQCWRKDPEERPTFEYLQAFLE 517
Score = 82.0 bits (201), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L
Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 348
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859
P E +R +R+P P CP+ L L QC +P +RP+F
Sbjct 460 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTF 509
>sp|Q9YI66|TYRO3_DANRE Tyrosine-protein kinase receptor TYRO3
OS=Danio rerio OX=7955 GN=tyro3 PE=2 SV=1
Length=874
Score = 144 bits (364), Expect = 8e-34, Method: Compositional matrix adjust.
Identities = 107/337 (32%), Positives = 167/337 (50%), Gaps = 32/337 (9%)
Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS--DPTVFHKRYLKKIRDLGEGHFGK 910
P + R+ R L P + D L +N D A D +F +R L R LG+G FG
Sbjct 453 PVSFTAARSFNRQFPEL-PESTLDSLGINSDLKAKLQDVLIF-ERLLTLGRMLGKGEFGS 510
Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIKYKGCC-ED 968
V + + + +G+ VAVK LK D +E ++ +H ++I+ G
Sbjct 511 VR-EAFLKSENNSGQKVAVKVLKTDINSSSDIEQCLKEAAYMKDFHHPNVIQLIGVSLHR 569
Query 969 QGEKSLQLVMEYVPL---GSLRDYLPRHSIG-----LAQLLL--FAQQICEGMAYLHAQH 1018
+ ++ L + M +P G L +L +G ++Q +L F I GM YL ++
Sbjct 570 RAQQRLPIPMVILPFMKHGDLHTFLLMSRLGDEPFTVSQQILIQFMLDIARGMEYLSNKN 629
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRDLAARN +L+ + V + DFGL+K + G +YYR PV W A E L + +
Sbjct 630 IIHRDLAARNCMLNENMSVCVADFGLSKKIYSG-DYYRQGSVSKLPVKWIALESLADNVY 688
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SDVW+FGVT++E++T Q+P G+ + + E L +GERL +P
Sbjct 689 TTQSDVWAFGVTMWEIMTR---GQTP------YPGVENSE-----IYEYLIKGERLKQPP 734
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
CP ++Y +M +CW RP+F++LI L+ + K
Sbjct 735 DCPADIYEIMHSCWSPVPKCRPSFQHLIDQLELLWAK 771
Score = 73.6 bits (179), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 73/259 (28%), Positives = 116/259 (45%), Gaps = 30/259 (12%)
Query 631 RDRGQELRV-VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV------RGPEN 683
+ GQ++ V VLK S DI E A+ M H ++ + GV + R P
Sbjct 520 NNSGQKVAVKVLKTDINSSSDIEQCLKE-AAYMKDFHHPNVIQLIGVSLHRRAQQRLPIP 578
Query 684 IMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQ----LASALSYLENKNLVHGNVCGR 738
+++ +++HG L +L R G P + Q +A + YL NKN++H ++ R
Sbjct 579 MVILPFMKHGDLHTFLLMSRLGDEPFTVSQQILIQFMLDIARGMEYLSNKNIIHRDLAAR 638
Query 739 NILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIP--WLAPECLPGGANSLS 792
N +L E S + ++D G+ G R+ V ++P W+A E L N +
Sbjct 639 NCMLN-----ENMS--VCVADFGLSKKIYSGDYYRQGSVSKLPVKWIALESL--ADNVYT 689
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLT 850
T D W FG T+ EI G+ P SE + + RL + P CP + + C +
Sbjct 690 TQSDVWAFGVTMWEIMTRGQTPYPGVENSEIYEYLIKGERLKQPPDCPADIYEIMHSCWS 749
Query 851 YEPTQRPSFRTILRDLTRL 869
P RPSF+ ++ L L
Sbjct 750 PVPKCRPSFQHLIDQLELL 768
>sp|Q108U6|MET_LOXAF Hepatocyte growth factor receptor OS=Loxodonta
africana OX=9785 GN=MET PE=3 SV=1
Length=1382
Score = 145 bits (366), Expect = 9e-34, Method: Compositional matrix adjust.
Identities = 95/282 (34%), Positives = 146/282 (52%), Gaps = 23/282 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G GHFG V Y ++G ++ AVK+L S + E I++ H +++
Sbjct 1085 IGRGHFGCV--YHGTLLDNGDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLS 1142
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ +
Sbjct 1143 LLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKF 1201
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKEYK 1077
+HRDLAARN +LD VK+ DFGLA+ V + EYY V + PV W A E L+ K
Sbjct 1202 VHRDLAARNCMLDEKFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESLQTQK 1260
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFGV L+EL+T +PP + +T L +G RL +P
Sbjct 1261 FTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLLQP 1306
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1307 EYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348
Score = 62.4 bits (150), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDVYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341
>sp|Q04736|YES_MOUSE Tyrosine-protein kinase Yes OS=Mus musculus
OX=10090 GN=Yes1 PE=1 SV=3
Length=541
Score = 141 bits (355), Expect = 9e-34, Method: Compositional matrix adjust.
Identities = 99/305 (32%), Positives = 147/305 (48%), Gaps = 32/305 (10%)
Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
H L V TV P + A D + L+ LG+G FG+V + ++ T VA
Sbjct 247 HKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK-----VA 301
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL D
Sbjct 302 IKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVVS---EEPIYIVTEFMSKGSLLD 356
Query 989 YLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ + + KI DFGLA
Sbjct 357 FLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLICKIADFGLA 416
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + Y R+ P+ W APE +F SDVWSFG+ EL+T
Sbjct 417 RLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGR------ 468
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ M + E +ERG R+P P CP ++ LM CW+ + RPTFE +
Sbjct 469 --------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYI 520
Query 1166 IPILK 1170
L+
Sbjct 521 QSFLE 525
Score = 73.9 bits (180), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 63/233 (27%), Positives = 106/233 (45%), Gaps = 19/233 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P + AF + A +M ++ H L ++ V P I VTE++ G L
Sbjct 299 KVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEFMSKGSLLD 356
Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G ++ + + +A Q+A ++Y+E N +H ++ NIL+ G + K
Sbjct 357 FLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILV-------GENLICK 409
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG E+ G
Sbjct 410 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILQTELVTKG 467
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
P E +R +R+P P CP+ L L + C +P +RP+F I
Sbjct 468 RVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYI 520
>sp|Q75ZY9|MET_CANLF Hepatocyte growth factor receptor OS=Canis
lupus familiaris OX=9615 GN=MET PE=1 SV=1
Length=1382
Score = 145 bits (366), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 96/284 (34%), Positives = 143/284 (50%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T ND AVK+L S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS--PVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW A RP+F L+ + + + G+
Sbjct 1305 QPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGE 1348
Score = 60.5 bits (145), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 99/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C RPSF ++ ++ +
Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAI 1341
>sp|Q07E01|MET_ORNAN Hepatocyte growth factor receptor OS=Ornithorhynchus
anatinus OX=9258 GN=MET PE=3 SV=1
Length=1382
Score = 145 bits (365), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 95/284 (33%), Positives = 144/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T ND AVK+L + S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICLRR-EGSPLVVLPYMKHGDLRNFIRNESHNPTVKDLIGFGLQVAKGMKYLASK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTSKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP ++ +M CW A RP+F L+ + + + G+
Sbjct 1305 QPEYCPDPLFEVMLKCWHPNAEMRPSFSELVSKIAVIFSTFIGE 1348
Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 54/224 (24%), Positives = 97/224 (43%), Gaps = 22/224 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRREGSPLVVLPYMKHGDLRNFIRNE-SHNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFT-------VKVADFGLARDMYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L ++ D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESL--QTQKFTSKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866
+ + RL +P CP L + +C RPSF ++ +
Sbjct 1295 VYLLQGRRLLQPEYCPDPLFEVMLKCWHPNAEMRPSFSELVSKI 1338
>sp|P14085|SRC_AVIST Tyrosine-protein kinase transforming protein
Src OS=Avian sarcoma virus (strain S2) OX=11882 GN=V-SRC
PE=3 SV=3
Length=557
Score = 141 bits (356), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 91/272 (33%), Positives = 137/272 (50%), Gaps = 31/272 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++
Sbjct 273 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQL 325
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLHAQH 1018
E+ + +V EY+ GSL D+L + +G L QL+ A QI GMAY+ +
Sbjct 326 YAVV---SEEPIYIVTEYMSKGSLLDFL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMN 381
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
Y+HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F
Sbjct 382 YVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRF 439
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SDVWSFG+ L EL T + M + + +ERG R+P P
Sbjct 440 TIKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPP 485
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+CP ++ LM CW + RPTFE L L+
Sbjct 486 ECPESLHDLMCQCWRKDPEERPTFEYLQAFLE 517
Score = 82.0 bits (201), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L
Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 348
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859
P E +R +R+P P CP+ L L QC +P +RP+F
Sbjct 460 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTF 509
>sp|P15054|SRC_AVIS2 Tyrosine-protein kinase transforming protein
Src OS=Avian sarcoma virus (strain PR2257) OX=11879 GN=V-SRC
PE=3 SV=3
Length=587
Score = 142 bits (357), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 99/306 (32%), Positives = 149/306 (49%), Gaps = 34/306 (11%)
Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
H L +V T P + A D + L+ LG+G FG+V + ++ T VA
Sbjct 239 HRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTT-----RVA 293
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL D
Sbjct 294 IKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS---EEPIYIVTEYMSKGSLLD 348
Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 349 FL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW + RPTFE
Sbjct 461 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEY 511
Query 1165 LIPILK 1170
L L+
Sbjct 512 LQAFLE 517
Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L
Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 348
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859
P E +R +R+P P CP+ L L QC +P +RP+F
Sbjct 460 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTF 509
>sp|Q4JIM5|ABL2_MOUSE Tyrosine-protein kinase ABL2 OS=Mus musculus
OX=10090 GN=Abl2 PE=1 SV=1
Length=1182
Score = 145 bits (365), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 93/287 (32%), Positives = 144/287 (50%), Gaps = 27/287 (9%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
TV SP D + + LG G +G+V + + + VAVK K D
Sbjct 270 TVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYS----LTVAVKTFKEDT-- 323
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSI 995
+ +E +++ + H ++++ G C E +V EY+P G+L DYL R +
Sbjct 324 MEVEEFLKEAAVMKEIKHPNLVQLLGVC--TLEPPFYIVTEYMPYGNLLDYLRECSREEV 381
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
LL A QI M YL +++IHRDLAARN L+ + +VK+ DFGL++ + + Y
Sbjct 382 TAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDTY 439
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
P+ W APE L F SDVW+FGV L+E+ T+ S P ++L
Sbjct 440 TAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMS----PYPGIDLS--- 492
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
++ +LLE+G R+ +P+ CP +VY LM+ CW+ + RP+F
Sbjct 493 -------QVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSF 532
Score = 93.6 bits (231), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 69/231 (30%), Positives = 108/231 (47%), Gaps = 18/231 (8%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
L V +K ++ F + A++M ++ H +L + GVC P +VTEY+ +G L
Sbjct 312 LTVAVKTFKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLL 370
Query 697 VWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+LR R V + +A Q++SA+ YLE KN +H ++ RN L+ G + +
Sbjct 371 DYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV-------GENHVV 423
Query 756 KLSDPGVG---LGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ G + P W APE L N+ S D W FG L EI
Sbjct 424 KVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESL--AYNTFSIKSDVWAFGVLLWEIATY 481
Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859
G +P S+ ++ +R+ PE P++ L C + P RPSF
Sbjct 482 GMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSF 532
>sp|Q02977|YRK_CHICK Proto-oncogene tyrosine-protein kinase Yrk
OS=Gallus gallus OX=9031 GN=YRK PE=2 SV=2
Length=536
Score = 141 bits (355), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 93/277 (34%), Positives = 139/277 (50%), Gaps = 29/277 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ ++ LG G FG+V + ++ T VAVK LK G + +E I++ L H
Sbjct 270 LQLLQKLGNGQFGEVWMGTWNGTTK-----VAVKTLKP--GTMSPEAFLEEAQIMKRLRH 322
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAY 1013
+ +++ E+ + +V E++ GSL D+L + L QL+ A QI GMAY
Sbjct 323 DKLVQLYAVVS---EEPIYIVTEFMSQGSLLDFLKDGDGRYLKLPQLVDMAAQIAAGMAY 379
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ +YIHRDL A N+L+ ++ + KI DFGLA+ + + Y R+ P+ W APE
Sbjct 380 IERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 437
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
KF SDVWSFG+ L EL+T + M + E +ERG R
Sbjct 438 LFGKFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 483
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ P CP ++ +M CW+ E RPTFE L L+
Sbjct 484 MQCPGGCPPSLHDVMVQCWKREPEERPTFEYLQSFLE 520
Score = 75.5 bits (184), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 64/233 (27%), Positives = 106/233 (45%), Gaps = 19/233 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P AF E A +M ++ H L ++ V P I VTE++ G L
Sbjct 294 KVAVKTLKPGTMSPE-AFLEEAQIMKRLRHDKLVQLYAVVSEEPIYI-VTEFMSQGSLLD 351
Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G ++ + + +A Q+A+ ++Y+E N +H ++ NIL+ G + K
Sbjct 352 FLKDGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILV-------GDNLVCK 404
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 405 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALFGKFTIKS--DVWSFGILLTELVTKG 462
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEPTQRPSFRTI 862
P + E +R +R+ P C P L + QC EP +RP+F +
Sbjct 463 RVPYPGMNNREVLEQVERGYRMQCPGGCPPSLHDVMVQCWKREPEERPTFEYL 515
>sp|P97523|MET_RAT Hepatocyte growth factor receptor OS=Rattus
norvegicus OX=10116 GN=Met PE=1 SV=1
Length=1382
Score = 145 bits (365), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 95/284 (33%), Positives = 146/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T +DG AVK+L + S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDSDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLVSK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITIYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+ L+ + ++ + G+
Sbjct 1305 QPEYCPDALYEVMLKCWHPKAEMRPSVSELVSRISSIFSTFIGE 1348
Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 54/227 (24%), Positives = 99/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1184 GFGLQVAKGMKYLVSKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPS ++ ++ +
Sbjct 1295 IYLLQGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSVSELVSRISSI 1341
>sp|P07947|YES_HUMAN Tyrosine-protein kinase Yes OS=Homo sapiens
OX=9606 GN=YES1 PE=1 SV=3
Length=543
Score = 141 bits (355), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 99/305 (32%), Positives = 147/305 (48%), Gaps = 32/305 (10%)
Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
H L V TV P + A D + L+ LG+G FG+V + ++ T VA
Sbjct 249 HKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK-----VA 303
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL D
Sbjct 304 IKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVVS---EEPIYIVTEFMSKGSLLD 358
Query 989 YLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ + + KI DFGLA
Sbjct 359 FLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLA 418
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + Y R+ P+ W APE +F SDVWSFG+ EL+T
Sbjct 419 RLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGR------ 470
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ M + E +ERG R+P P CP ++ LM CW+ + RPTFE +
Sbjct 471 --------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYI 522
Query 1166 IPILK 1170
L+
Sbjct 523 QSFLE 527
Score = 73.6 bits (179), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 63/233 (27%), Positives = 106/233 (45%), Gaps = 19/233 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P + AF + A +M ++ H L ++ V P I VTE++ G L
Sbjct 301 KVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEFMSKGSLLD 358
Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G ++ + + +A Q+A ++Y+E N +H ++ NIL+ G + K
Sbjct 359 FLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILV-------GENLVCK 411
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG E+ G
Sbjct 412 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILQTELVTKG 469
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
P E +R +R+P P CP+ L L + C +P +RP+F I
Sbjct 470 RVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYI 522
>sp|Q28923|YES_CANLF Tyrosine-protein kinase Yes OS=Canis lupus
familiaris OX=9615 GN=YES1 PE=1 SV=3
Length=539
Score = 140 bits (354), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 99/305 (32%), Positives = 146/305 (48%), Gaps = 32/305 (10%)
Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
H L V TV P + A D + L+ LG+G FG+V + ++ T VA
Sbjct 245 HKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK-----VA 299
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL D
Sbjct 300 IKTLK--LGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVS---EEPIYIVTEFMSKGSLLD 354
Query 989 YLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ + + KI DFGLA
Sbjct 355 FLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLA 414
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + Y R+ P+ W APE +F SDVWSFG+ EL T
Sbjct 415 RLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELTTKGR------ 466
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ M + E +ERG R+P P CP ++ LM CW+ + RPTFE +
Sbjct 467 --------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYI 518
Query 1166 IPILK 1170
L+
Sbjct 519 QSFLE 523
Score = 70.9 bits (172), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 59/217 (27%), Positives = 99/217 (46%), Gaps = 18/217 (8%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKM 712
AF + A +M ++ H L ++ V P I VTE++ G L +L+ G ++ + +
Sbjct 312 AFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEFMSKGSLLDFLKEGDGKYLKLPQLV 370
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
+A Q+A ++Y+E N +H ++ NIL+ G + K++D G+ E
Sbjct 371 DMAAQIADGMAYIERMNYIHRDLRAANILV-------GENLVCKIADFGLARLIEDNEYT 423
Query 773 VER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
+ I W APE G ++ + D W FG E+ G P E
Sbjct 424 ARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILQTELTTKGRVPYPGMVNREVLEQV 481
Query 828 QRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
+R +R+P P CP+ L L + C +P +RP+F I
Sbjct 482 ERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYI 518
>sp|P13116|SRC2_XENLA Tyrosine-protein kinase Src-2 OS=Xenopus
laevis OX=8355 GN=src-b PE=2 SV=3
Length=532
Score = 140 bits (354), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 91/272 (33%), Positives = 136/272 (50%), Gaps = 31/272 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++
Sbjct 272 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQL 324
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLHAQH 1018
E+ + +V EY+ GSL D+L + +G L QL+ A QI GMAY+ +
Sbjct 325 YAVVS---EEPIYIVTEYMSKGSLLDFL-KGEMGRYLRLPQLVDMAAQIASGMAYVERMN 380
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
Y+HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F
Sbjct 381 YVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRF 438
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SDVWSFG+ L EL T + M + + +ERG R+P P
Sbjct 439 TIKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPP 484
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
CP ++ LM CW + RPTFE L L+
Sbjct 485 DCPESLHDLMFQCWRKDPEERPTFEYLQAFLE 516
Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L
Sbjct 290 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 347
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 348 FLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 400
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 401 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 458
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859
P E +R +R+P P CP+ L L QC +P +RP+F
Sbjct 459 RVPYPGMVNREVLDQVERGYRMPCPPDCPESLHDLMFQCWRKDPEERPTF 508
>sp|P54757|EPHA5_RAT Ephrin type-A receptor 5 OS=Rattus norvegicus
OX=10116 GN=Epha5 PE=1 SV=1
Length=1005
Score = 144 bits (363), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 93/294 (32%), Positives = 149/294 (51%), Gaps = 31/294 (11%)
Query 888 DPTVFHKRYLKKI--------RDLGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCG 937
DPT + K+I R +G G FG+V C G E+ VA K LK
Sbjct 660 DPTQAVHEFGKEIEASCITIERVIGAGEFGEV---CSGRLKLPGKRELPVATKTLKVGYT 716
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995
+ R + E I+ H +II +G K + +V EY+ GSL +L ++
Sbjct 717 EKQRRDFLSEASIMGQFDHPNIIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQF 774
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL++ + + E
Sbjct 775 TVIQLVGMLRGIAAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAA 834
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
G P+ W APE + KF ASDVWS+G+ ++E++++ + P
Sbjct 835 YTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSY---GERP----------- 880
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+MT + + +E G RLP P CP +Y LM +CW+ + + RP F++++ +L
Sbjct 881 YWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDDIVNML 934
Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 79/286 (28%), Positives = 128/286 (45%), Gaps = 33/286 (12%)
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSH 667
RV G+G E G++ +PG+ +EL V K L + + F AS+M Q H
Sbjct 681 RVIGAG--EFGEVCSGRLKLPGK---RELPVATKTLKVGYTEKQRRDFLSEASIMGQFDH 735
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
++ + GV + ++VTEY+E+G LD +L++ G + + + + +A+ + YL +
Sbjct 736 PNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLSD 795
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIP--WLA 780
VH ++ RNIL+ ++ K+SD G+ E R +IP W A
Sbjct 796 MGYVHRDLAARNILI-------NSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTA 848
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP 839
PE + ++A D W +G + E+ GE P + + + +RLP P CP
Sbjct 849 PEAI--AFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCP 906
Query 840 -QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884
L L C + RP F I+ N+ D L NP S
Sbjct 907 AALYQLMLDCWQKDRNSRPKFDDIV---------NMLDKLIRNPSS 943
>sp|P23049|SEA_AVIET Tyrosine-protein kinase transforming protein
SEA OS=Avian erythroblastosis virus (strain S13) OX=11863
GN=V-SEA PE=3 SV=2
Length=370
Score = 137 bits (344), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 99/292 (34%), Positives = 145/292 (50%), Gaps = 39/292 (13%)
Query 901 RDLGEGHFGKVSLYCY-DPTNDGTGEM-VAVKALKADCGPQHRSGWKQEID-------IL 951
R +G GHFG V Y DP G + AVK+L HR + +E++ ++
Sbjct 64 RVIGRGHFGSVYHGTYMDPL---LGNLHCAVKSL-------HRITYLEEVEEFLREGILM 113
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICE 1009
+ +H ++ G C + L +V+ Y+ G LR ++ S + +L+ F Q+
Sbjct 114 KGFHHPQVLSLLGVCLPRHGLPL-VVLPYMRHGDLRHFVRAQERSPTVKELIGFGLQVAL 172
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE--DGDSPVFW 1067
GM YL + ++HRDLAARN +LD VK+ DFGLA+ V G EYY +R+ PV W
Sbjct 173 GMEYLAQKKFVHRDLAARNCMLDETLTVKVADFGLARDV-FGKEYYSIRQHRHAKLPVRW 231
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
A E L+ KF SDVWSFGV ++ELLT S ++ +
Sbjct 232 MALESLQTQKFTTKSDVWSFGVLMWELLTRGASPYP--------------EVDPYDMARY 277
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L RG RLP+P CP +Y +M +CW RP+F L+ L+ V +G+
Sbjct 278 LLRGRRLPQPQPCPDTLYGVMLSCWAPTPEERPSFSGLVCELERVLASLEGE 329
Score = 72.4 bits (176), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 59/226 (26%), Positives = 97/226 (43%), Gaps = 20/226 (9%)
Query 655 FYETASLMSQVSHTHLAFVHGVCV-RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F LM H + + GVC+ R ++V Y+ HG L ++R + + +
Sbjct 106 FLREGILMKGFHHPQVLSLLGVCLPRHGLPLVVLPYMRHGDLRHFVRAQERSPTVKELIG 165
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----- 768
Q+A + YL K VH ++ RN +L + +K++D G+
Sbjct 166 FGLQVALGMEYLAQKKFVHRDLAARNCML-------DETLTVKVADFGLARDVFGKEYYS 218
Query 769 -REERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
R+ R ++P W+A E L +T D W FG + E+ G +P P +
Sbjct 219 IRQHRHAKLPVRWMALESL--QTQKFTTKSDVWSFGVLMWELLTRGASPYPEVDPYDMAR 276
Query 826 FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ R RLP+P CP L + C P +RPSF ++ +L R+
Sbjct 277 YLLRGRRLPQPQPCPDTLYGVMLSCWAPTPEERPSFSGLVCELERV 322
>sp|Q60629|EPHA5_MOUSE Ephrin type-A receptor 5 OS=Mus musculus
OX=10090 GN=Epha5 PE=1 SV=2
Length=876
Score = 143 bits (361), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 87/273 (32%), Positives = 142/273 (52%), Gaps = 23/273 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
R +G G FG+V C G E+ VA+K LK + R + E I+ H +
Sbjct 518 RVIGAGEFGEV---CSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPN 574
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHA 1016
II +G K + +V EY+ GSL +L ++ + QL+ + I GM YL
Sbjct 575 IIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLSD 632
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W APE +
Sbjct 633 MGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFR 692
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
KF +SDVWS+G+ ++E++++ + P +MT + + +E G RLP
Sbjct 693 KFTSSSDVWSYGIVMWEVVSY---GERP-----------YWEMTNQDVIKAVEEGYRLPS 738
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P CP +Y LM +CW+ + + RP F+ ++ +L
Sbjct 739 PMDCPAALYQLMLDCWQKDRNSRPKFDEIVNML 771
Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 78/288 (27%), Positives = 131/288 (45%), Gaps = 37/288 (13%)
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSH 667
RV G+G E G++ +PG+ +EL V +K L + + F AS+M Q H
Sbjct 518 RVIGAG--EFGEVCSGRLKLPGK---RELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDH 572
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
++ + GV + ++VTEY+E+G LD +L++ G + + + + +A+ + YL +
Sbjct 573 PNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLSD 632
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-------RVERIP--W 778
VH ++ RNIL+ ++ K+SD GL + ++ R +IP W
Sbjct 633 MGYVHRDLAARNILI-------NSNLVCKVSD--FGLSRVLEDDPEAAYTTRGGKIPIRW 683
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-S 837
APE + +++ D W +G + E+ GE P + + + +RLP P
Sbjct 684 TAPEAI--AFRKFTSSSDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMD 741
Query 838 CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884
CP L L C + RP F I+ N+ D L NP S
Sbjct 742 CPAALYQLMLDCWQKDRNSRPKFDEIV---------NMLDKLIRNPSS 780
>sp|O13146|EPHA3_DANRE Ephrin type-A receptor 3 OS=Danio rerio
OX=7955 GN=epha3 PE=1 SV=1
Length=981
Score = 144 bits (362), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 93/293 (32%), Positives = 147/293 (50%), Gaps = 29/293 (10%)
Query 888 DPTVFHKRYLKKI--------RDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGP 938
DP + + K+I R +G G FG+V S P+ VA+K+LKA
Sbjct 609 DPNQAVRDFAKEIEVSNIRIERVIGAGEFGEVCSGRLRLPSKREI--QVAIKSLKAGYSE 666
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IG 996
R + E I+ H +II+ +G K + +V EY+ GSL +L +H
Sbjct 667 HQRRDFLSEASIMGQFDHPNIIRLEGVVTRC--KPVMIVTEYMENGSLDTFLKKHDGQFT 724
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
+ QLL + I GM YL +Y+HRDLAARN+L++ + + K+ DFGL++ + + E
Sbjct 725 VIQLLGMLRGIAAGMQYLSEMNYVHRDLAARNILVNRNLVCKVSDFGLSRVLEDDPEAAY 784
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
G P+ W APE + KF ASDVWS+G+ ++E++++ + P
Sbjct 785 TTRGGKIPIRWTAPEAITYRKFTSASDVWSYGIVMWEVISY---GERP-----------Y 830
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+M+ + + ++ G RLP P CP ++ LM +CWE S RP F ++ L
Sbjct 831 WEMSNQDVIKAVDEGYRLPAPMDCPVVLHQLMLDCWEKNRSDRPKFGQIVNTL 883
Score = 91.7 bits (226), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 71/245 (29%), Positives = 112/245 (46%), Gaps = 19/245 (8%)
Query 635 QELRVVLKVLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+E++V +K L + + F AS+M Q H ++ + GV R ++VTEY+E+G
Sbjct 651 REIQVAIKSLKAGYSEHQRRDFLSEASIMGQFDHPNIIRLEGVVTRCKPVMIVTEYMENG 710
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
LD +L++ G + + + + +A+ + YL N VH ++ RNIL+ R +
Sbjct 711 SLDTFLKKHDGQFTVIQLLGMLRGIAAGMQYLSEMNYVHRDLAARNILVNR-------NL 763
Query 754 FIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLE 806
K+SD G+ E R +IP W APE + ++A D W +G + E
Sbjct 764 VCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIT--YRKFTSASDVWSYGIVMWE 821
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILR 864
+ GE P S + +RLP P CP L L C + RP F I+
Sbjct 822 VISYGERPYWEMSNQDVIKAVDEGYRLPAPMDCPVVLHQLMLDCWEKNRSDRPKFGQIVN 881
Query 865 DLTRL 869
L RL
Sbjct 882 TLDRL 886
>sp|Q7YR43|DDR1_PANTR Epithelial discoidin domain-containing receptor
1 OS=Pan troglodytes OX=9598 GN=DDR1 PE=3 SV=1
Length=909
Score = 143 bits (361), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 99/309 (32%), Positives = 141/309 (46%), Gaps = 47/309 (15%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTND------------GTGEMVAVKALKADCGPQ 939
F + L+ LGEG FG+V L D D G +VAVK L+ D
Sbjct 601 FPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKN 660
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------ 993
R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L H
Sbjct 661 ARNDFLKEVKIMSRLKDPNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSAHQLEDKA 718
Query 994 --------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
+I LL A QI GM YL +++HRDLA RN L+ + +KI
Sbjct 719 AEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKI 778
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+L C
Sbjct 779 ADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCR 837
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER---LPRPDKCPCEVYHLMKNCWETEA 1156
+ + G + + E R L RP CP +Y LM CW E+
Sbjct 838 A---------QPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRES 888
Query 1157 SFRPTFENL 1165
RP F L
Sbjct 889 EQRPPFSQL 897
Score = 76.6 bits (187), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 76/270 (28%), Positives = 121/270 (45%), Gaps = 44/270 (16%)
Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+G L V +K+L P A F + +MS++ ++ + GVCV+ M+T+Y+E
Sbjct 642 KGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYME 701
Query 692 HGPLDVWLRRER------------GHVP----MAWKMV--VAQQLASALSYLENKNLVHG 733
+G L+ +L + G +++ M+ VA Q+AS + YL N VH
Sbjct 702 NGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHR 761
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGG 787
++ RN L+ G + IK++D G+ + + V I W+A EC+ G
Sbjct 762 DLATRNCLV-------GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG 814
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-----EHFYQRQHRLP----EPSC 838
+TA D W FG TL E+ A + E+ F++ Q R P+C
Sbjct 815 --KFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPAC 872
Query 839 PQ-LATLTSQCLTYEPTQRPSFRTILRDLT 867
PQ L L +C + E QRP F + R L
Sbjct 873 PQGLYELMLRCWSRESEQRPPFSQLHRFLA 902
>sp|Q08345|DDR1_HUMAN Epithelial discoidin domain-containing receptor
1 OS=Homo sapiens OX=9606 GN=DDR1 PE=1 SV=1
Length=913
Score = 143 bits (361), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 99/309 (32%), Positives = 141/309 (46%), Gaps = 47/309 (15%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTND------------GTGEMVAVKALKADCGPQ 939
F + L+ LGEG FG+V L D D G +VAVK L+ D
Sbjct 605 FPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKN 664
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------ 993
R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L H
Sbjct 665 ARNDFLKEVKIMSRLKDPNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSAHQLEDKA 722
Query 994 --------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
+I LL A QI GM YL +++HRDLA RN L+ + +KI
Sbjct 723 AEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKI 782
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+L C
Sbjct 783 ADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCR 841
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER---LPRPDKCPCEVYHLMKNCWETEA 1156
+ + G + + E R L RP CP +Y LM CW E+
Sbjct 842 A---------QPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRES 892
Query 1157 SFRPTFENL 1165
RP F L
Sbjct 893 EQRPPFSQL 901
Score = 76.6 bits (187), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 76/270 (28%), Positives = 121/270 (45%), Gaps = 44/270 (16%)
Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+G L V +K+L P A F + +MS++ ++ + GVCV+ M+T+Y+E
Sbjct 646 KGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYME 705
Query 692 HGPLDVWLRRER------------GHVP----MAWKMV--VAQQLASALSYLENKNLVHG 733
+G L+ +L + G +++ M+ VA Q+AS + YL N VH
Sbjct 706 NGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHR 765
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGG 787
++ RN L+ G + IK++D G+ + + V I W+A EC+ G
Sbjct 766 DLATRNCLV-------GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG 818
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-----EHFYQRQHRLP----EPSC 838
+TA D W FG TL E+ A + E+ F++ Q R P+C
Sbjct 819 --KFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPAC 876
Query 839 PQ-LATLTSQCLTYEPTQRPSFRTILRDLT 867
PQ L L +C + E QRP F + R L
Sbjct 877 PQGLYELMLRCWSRESEQRPPFSQLHRFLA 906
>sp|P06213|INSR_HUMAN Insulin receptor OS=Homo sapiens OX=9606
GN=INSR PE=1 SV=4
Length=1382
Score = 144 bits (363), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 94/283 (33%), Positives = 146/283 (52%), Gaps = 29/283 (10%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+R+LG+G FG V G E VAVK + + R + E +++ H
Sbjct 1026 LRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHH 1085
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------PRHSIGLAQLLLFAQQI 1007
+++ G +G+ +L +VME + G L+ YL R L +++ A +I
Sbjct 1086 VVRLLGVVS-KGQPTL-VVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEI 1143
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+GMAYL+A+ ++HRDLAARN ++ +D VKIGDFG+ + + E +YYR G PV W
Sbjct 1144 ADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYET-DYYRKGGKGLLPVRW 1202
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE LK+ F +SD+WSFGV L+E+ + + G++ Q + +
Sbjct 1203 MAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQ---------GLSNEQ-----VLKF 1248
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ G L +PD CP V LM+ CW+ RPTF ++ +LK
Sbjct 1249 VMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLK 1291
Score = 91.3 bits (225), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 82/301 (27%), Positives = 128/301 (43%), Gaps = 46/301 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +++IT L LGQG+ VYEG R G+ E RV +K
Sbjct 1018 VSREKITLLRELGQGSFGMVYEGNARDIIKGE-------------------AETRVAVKT 1058
Query 644 LDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
++ S + F AS+M + H+ + GV +G ++V E + HG L +LR
Sbjct 1059 VNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSL 1118
Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
R P +M+ +A ++A ++YL K VH ++ RN ++A
Sbjct 1119 RPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAH-------DF 1171
Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+ D G+ + + + + W+APE L G +T+ D W FG L EI
Sbjct 1172 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGV--FTTSSDMWSFGVVLWEI 1229
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQLAT-LTSQCLTYEPTQRPSFRTILRD 865
E P Q S + F L +P +CP+ T L C + P RP+F I+
Sbjct 1230 TSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNL 1289
Query 866 L 866
L
Sbjct 1290 L 1290
>sp|Q93105|INSR_AEDAE Insulin-like receptor OS=Aedes aegypti OX=7159
GN=InR PE=2 SV=2
Length=1393
Score = 144 bits (363), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 98/305 (32%), Positives = 155/305 (51%), Gaps = 35/305 (11%)
Query 880 VNPDSPASDPTV----FHKRYLKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKA 934
VNPD V + ++ ++ +LG+G FG V + + A+K +
Sbjct 1004 VNPDYAGVQYKVDDWEVERNHIIQLEELGQGSFGMVYKGILTQLRGEKCNQPCAIKTVNE 1063
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994
+ + + E +++ H+++ G QG+ +L ++ME + G L+ YL RH
Sbjct 1064 SATAREKDSFLLEASVMKQFNTHHVVRLLGVVS-QGDPTL-VIMELMANGDLKSYLRRHR 1121
Query 995 IG-------------LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
L Q++ A +I +GMAYL A+ ++HRDLAARN ++ +D VKIGD
Sbjct 1122 PDYENGEDPSPQPPTLRQIIQMAIEIADGMAYLSAKKFVHRDLAARNCMVADDMTVKIGD 1181
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FG+ + + E +YYR G PV W APE LK+ F +SDV+S+GV L+E+ T
Sbjct 1182 FGMTRDIYE-TDYYRKGTKGFLPVRWMAPESLKDGIFSSSSDVFSYGVVLWEMATLA--- 1237
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
S P + G+ Q VLR + G + RP+ CP +Y+LM+ CW+ + RPT
Sbjct 1238 -SQPYQ-----GLTNDQ--VLR---YVIDGGVMERPENCPDNLYNLMRRCWQHRPTARPT 1286
Query 1162 FENLI 1166
F +I
Sbjct 1287 FMEII 1291
Score = 77.0 bits (188), Expect = 8e-13, Method: Compositional matrix adjust.
Identities = 77/305 (25%), Positives = 128/305 (42%), Gaps = 52/305 (17%)
Query 584 VDQKEITQLSHLGQGTRTNVYEG---RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
V++ I QL LGQG+ VY+G +LR E P K +E +D
Sbjct 1020 VERNHIIQLEELGQGSFGMVYKGILTQLRGEKCNQPCAIKTVNESATAREKD-------- 1071
Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
+F AS+M Q + H+ + GV +G +++ E + +G L +LR
Sbjct 1072 -------------SFLLEASVMKQFNTHHVVRLLGVVSQGDPTLVIMELMANGDLKSYLR 1118
Query 701 R-----ERGHVP------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
R E G P + + +A ++A ++YL K VH ++ RN ++A
Sbjct 1119 RHRPDYENGEDPSPQPPTLRQIIQMAIEIADGMAYLSAKKFVHRDLAARNCMVA------ 1172
Query 750 GTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGANSLSTAMDKWGFGAT 803
+K+ D G+ R+ +P W+APE L G S++ D + +G
Sbjct 1173 -DDMTVKIGDFGMTRDIYETDYYRKGTKGFLPVRWMAPESLKDGI--FSSSSDVFSYGVV 1229
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRT 861
L E+ P Q + + + + P +CP L L +C + PT RP+F
Sbjct 1230 LWEMATLASQPYQGLTNDQVLRYVIDGGVMERPENCPDNLYNLMRRCWQHRPTARPTFME 1289
Query 862 ILRDL 866
I+ +L
Sbjct 1290 IISEL 1294
>sp|Q9I7F7|ACKL_DROME Activated Cdc42 kinase-like OS=Drosophila
melanogaster OX=7227 GN=Ack-like PE=1 SV=3
Length=1337
Score = 144 bits (363), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 94/272 (35%), Positives = 142/272 (52%), Gaps = 29/272 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+ LG G FG V + N+ VA+K L + + + +E I+ ++ HE+I+
Sbjct 137 KQLGTGEFGIVQQGVWSNGNERI--QVAIKCLCRERMQSNPMEFLKEAAIMHSIEHENIV 194
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-----FAQQICEGMAYLH 1015
+ G SL LV E L SL + L + ++ L + FA QIC GM YL
Sbjct 195 RLYGVV--LATDSLMLVTELAHLRSLLECLKDSGLRVSFLTIPTLCEFALQICNGMRYLE 252
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD--SPVFWYAPECL 1073
+ IHRDLAARN+L+ + VKI DFGL++A+ G +YY+ + + P+ W APEC+
Sbjct 253 QKRLIHRDLAARNILVFSKDKVKISDFGLSRALGVGKDYYKTNFNVNLKLPIAWCAPECI 312
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ-GQMTVLRLTELLE--R 1130
+F ASDVW+FGV L+E+ ++ G +T L++ E ++
Sbjct 313 NYLRFTNASDVWAFGVCLWEMFSY---------------GFQPWAALTGLQILEAIDAPN 357
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
+RL +PD CP E Y LM CW+ +A+ RP F
Sbjct 358 YQRLEQPDCCPSEYYTLMMKCWQDDAAKRPRF 389
Score = 66.6 bits (161), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 69/276 (25%), Positives = 115/276 (42%), Gaps = 39/276 (14%)
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-----DVWLRRERGHVP 707
+ F + A++M + H ++ ++GV + ++VTE L D LR +P
Sbjct 176 MEFLKEAAIMHSIEHENIVRLYGVVLATDSLMLVTELAHLRSLLECLKDSGLRVSFLTIP 235
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VG 763
+ + Q+ + + YLE K L+H ++ RNIL+ + +K+SD G +G
Sbjct 236 TLCEFAL--QICNGMRYLEQKRLIHRDLAARNILVF-------SKDKVKISDFGLSRALG 286
Query 764 LGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP---- 814
+G + I W APEC+ + A D W FG L E+ G P
Sbjct 287 VGKDYYKTNFNVNLKLPIAWCAPECI--NYLRFTNASDVWAFGVCLWEMFSYGFQPWAAL 344
Query 815 --LQSRSPSEKEHFYQRQHRLPEPSC--PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
LQ + ++ RL +P C + TL +C + +RP F I L ++
Sbjct 345 TGLQILEAIDAPNY----QRLEQPDCCPSEYYTLMMKCWQDDAAKRPRFGEIYDQLPDMK 400
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906
P L V VN P D ++ + + + D G
Sbjct 401 PEQLKAV--VNCTEPKKDHLLYRQGDIISVLDRNTG 434
>sp|P97504|BMX_MOUSE Cytoplasmic tyrosine-protein kinase BMX OS=Mus
musculus OX=10090 GN=Bmx PE=2 SV=1
Length=651
Score = 141 bits (356), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 90/278 (32%), Positives = 139/278 (50%), Gaps = 27/278 (10%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+++LG G FG V L + D VAVK +K G + QE + L H +
Sbjct 396 LKELGNGQFGVVQLGQWKGQYD-----VAVKMIKE--GAMSEDEFFQEAQTMMKLSHPKL 448
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQ 1017
+K+ G C + + +V EY+ G L +YL H GL QLL +CEGMA+L +
Sbjct 449 VKFYGVCSKK--YPIYIVTEYITNGCLLNYLKSHGKGLESCQLLEMCYDVCEGMAFLESH 506
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+IHRDLAARN L+D+D VK+ DFG+ + V + Y PV W APE +K
Sbjct 507 QFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQ--YVSSVGTKFPVKWSAPEVFHYFK 564
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ SDVW+FG+ ++E+ + + P + V+++++ G RL RP
Sbjct 565 YSSKSDVWAFGILMWEVFS---LGKQP-------YDLYDNSEVVVKVSQ----GHRLYRP 610
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+Y +M +CW RPTF+ L+ ++ + E+
Sbjct 611 QLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPLREQ 648
Score = 66.2 bits (160), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 57/230 (25%), Positives = 101/230 (44%), Gaps = 24/230 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F++ A M ++SH L +GVC + +VTEY+ +G L +L+ + + +
Sbjct 433 FFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSHGKGLESCQLLEM 492
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ +++LE+ +H ++ RN L+ + +K+SD G+ L ++ V
Sbjct 493 CYDVCEGMAFLESHQFIHRDLAARNCLV-------DSDLSVKVSDFGMTRYVLD-DQYVS 544
Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
+ W APE S+ D W FG + E+ G+ P SE
Sbjct 545 SVGTKFPVKWSAPEVF--HYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVS 602
Query 829 RQHRLPEPSCPQLATLTSQCLTYE-----PTQRPSFRTILRDLTRLQPHN 873
+ HRL PQLA+ T + Y P +RP+F+ +L + L+ +
Sbjct 603 QGHRLYR---PQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPLREQD 649
>sp|Q07E48|MET_DASNO Hepatocyte growth factor receptor OS=Dasypus
novemcinctus OX=9361 GN=MET PE=3 SV=1
Length=1381
Score = 144 bits (362), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 95/284 (33%), Positives = 144/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T +D AVK+L S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1305 QPEYCPDRLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348
Score = 62.0 bits (149), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 101/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP +L + +C + RPSF ++ ++ +
Sbjct 1295 VYLLQGRRLLQPEYCPDRLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341
>sp|P33497|RYK_AVIR3 Tyrosine-protein kinase transforming protein
RYK OS=Avian retrovirus RPL30 OX=31671 GN=V-RYK PE=2 SV=1
Length=442
Score = 138 bits (347), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 95/288 (33%), Positives = 143/288 (50%), Gaps = 29/288 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQE 947
V + L + LGEG FG V + +GT + VAVK +K D HR + E
Sbjct 38 VVIDRNALSLGKVLGEGEFGSV-MEGRLSQPEGTPQKVAVKTMKLD-NFSHREIEEFLSE 95
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSL---QLVMEYVPLGSLRDYLPRHSIGLA------ 998
++ H ++IK G C + + + +V+ ++ G L +L R + +A
Sbjct 96 AACIKDFDHPNVIKLLGVCIELSSQQIPKPMVVLPFMKYGDLHSFLLRSRLEMAPQFVPL 155
Query 999 -QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
LL F I GM YL ++ ++HRDLAARN +L +D V + DFGL+K + G +YYR
Sbjct 156 QMLLKFMVDIALGMEYLSSRQFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQ 214
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
PV W A E L + + SDVW+FGVT++E+ T +P G+
Sbjct 215 GRIAKMPVKWIAIESLADRVYTTKSDVWAFGVTMWEIATR---GMTP------YPGVQNH 265
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + E L G+RL +P+ C E+Y +M +CW E + RPTF L
Sbjct 266 E-----IYEYLFHGQRLKKPENCLDELYDIMSSCWRAEPADRPTFSQL 308
Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 81/329 (25%), Positives = 141/329 (43%), Gaps = 51/329 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+D+ ++ LG+G +V EGRL + G P++ + +K+
Sbjct 40 IDRNALSLGKVLGEGEFGSVMEGRLS-QPEGTPQKVAVK-----------------TMKL 81
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV-----RGPENIMVTEYVEHGPLDVW 698
+ SH +I F A+ + H ++ + GVC+ + P+ ++V ++++G L +
Sbjct 82 DNFSHREIE-EFLSEAACIKDFDHPNVIKLLGVCIELSSQQIPKPMVVLPFMKYGDLHSF 140
Query 699 LRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L R R VP+ + +A + YL ++ +H ++ RN +L R + +
Sbjct 141 LLRSRLEMAPQFVPLQMLLKFMVDIALGMEYLSSRQFLHRDLAARNCML-RDDMTVCVAD 199
Query 754 FIKLSDPGVGLGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
F LS + G R+ R+ ++P W+A E L +T D W FG T+ EI G
Sbjct 200 F-GLSKK-IYSGDYYRQGRIAKMPVKWIAIESL--ADRVYTTKSDVWAFGVTMWEIATRG 255
Query 812 EAPLQSRSPSEKEH------FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
P P + H F+ ++ + PE +L + S C EP RP+F +
Sbjct 256 MTPY----PGVQNHEIYEYLFHGQRLKKPENCLDELYDIMSSCWRAEPADRPTFSQLKVH 311
Query 866 LTRL-----QPHNLADVLTVNPDSPASDP 889
L +L P DV+ VN P P
Sbjct 312 LEKLLESLPAPRGSKDVIYVNTSLPEESP 340
>sp|Q02858|TIE2_MOUSE Angiopoietin-1 receptor OS=Mus musculus
OX=10090 GN=Tek PE=1 SV=2
Length=1122
Score = 143 bits (361), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 102/309 (33%), Positives = 148/309 (48%), Gaps = 43/309 (14%)
Query 888 DPTVFHKRYLKKIR---DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
DPT++ I+ +GEG+FG+V DG A+K +K +
Sbjct 810 DPTIYPVLDWNDIKFQDVIGEGNFGQV--LKARIKKDGLRMDAAIKRMKEYASKDDHRDF 867
Query 945 KQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---------- 993
E+++L L +H +II G CE +G L L +EY P G+L D+L +
Sbjct 868 AGELEVLCKLGHHPNIINLLGACEHRG--YLYLAIEYAPHGNLLDFLRKSRVLETDPAFA 925
Query 994 -------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
++ QLL FA + GM YL + +IHRDLAARN+L+ + + KI DFGL++
Sbjct 926 IANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYIAKIADFGLSR 985
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
G E Y + G PV W A E L + SDVWS+GV L+E+++
Sbjct 986 ----GQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVS---------- 1031
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L G MT L E L +G RL +P C EVY LM+ CW + RP+F ++
Sbjct 1032 ----LGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQIL 1087
Query 1167 PILKTVHEK 1175
L + E+
Sbjct 1088 VSLNRMLEE 1096
Score = 65.1 bits (157), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 79/335 (24%), Positives = 135/335 (40%), Gaps = 58/335 (17%)
Query 557 ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD- 615
+ L + R A+ +P L ++ + +++ + GQ + + + LR++ +
Sbjct 795 NSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKR 854
Query 616 -PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
E DD RD EL V+ K+ HH ++ +
Sbjct 855 MKEYASKDDH------RDFAGELEVLCKL---GHH------------------PNIINLL 887
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRER--------GHVPMAWKMVVAQQL-------A 719
G C + EY HG L +LR+ R + +QQL A
Sbjct 888 GACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVA 947
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA-LSREERVERIP- 777
+ YL K +H ++ RNIL+ G + K++D G+ G + ++ + R+P
Sbjct 948 RGMDYLSQKQFIHRDLAARNILV-------GENYIAKIADFGLSRGQEVYVKKTMGRLPV 1000
Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836
W+A E L + +T D W +G L EI G P + +E + +RL +P
Sbjct 1001 RWMAIESL--NYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKP 1058
Query 837 -SC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+C ++ L QC +P +RPSF IL L R+
Sbjct 1059 LNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRM 1093
>sp|P16277|BLK_MOUSE Tyrosine-protein kinase Blk OS=Mus musculus
OX=10090 GN=Blk PE=1 SV=4
Length=499
Score = 139 bits (350), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 93/298 (31%), Positives = 143/298 (48%), Gaps = 31/298 (10%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
A D ++ LK +R LG G FG+V + Y VA+K LK G +
Sbjct 224 AQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYK-----NNMKVAIKTLKE--GTMSPEAFL 276
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLL 1002
E ++++TL HE +++ + + +V EY+ G L D+L + L +L+
Sbjct 277 GEANVMKTLQHERLVRLYAVVTRE---PIYIVTEYMARGCLLDFLKTDEGSRLSLPRLID 333
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
+ Q+ EGMAY+ + IHRDL A N+L+ KI DFGLA+ + Y +E
Sbjct 334 MSAQVAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARII---DSEYTAQEGAK 390
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
P+ W APE + F +DVWSFGV L E++T+ + M+
Sbjct 391 FPIKWTAPEAIHFGVFTIKADVWSFGVLLMEIVTYGR--------------VPYPGMSNP 436
Query 1123 RLTELLERGERLPRPDKCPCEVYH-LMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+ LE G R+P P+ CP E+Y+ ++ CW RPTFE L +L+ + +GQ
Sbjct 437 EVIRSLEHGYRMPCPETCPPELYNDIITECWRGRPEERPTFEFLQSVLEDFYTATEGQ 494
Score = 72.0 bits (175), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 105/226 (46%), Gaps = 25/226 (11%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKM 712
AF A++M + H L ++ V R P I VTEY+ G L +L+ + G + + +
Sbjct 274 AFLGEANVMKTLQHERLVRLYAVVTREPIYI-VTEYMARGCLLDFLKTDEGSRLSLPRLI 332
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
++ Q+A ++Y+E N +H ++ NIL++ + K++D GL + E
Sbjct 333 DMSAQVAEGMAYIERMNSIHRDLRAANILVSE-------TLCCKIAD--FGLARIIDSEY 383
Query 773 VER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ I W APE + G ++ D W FG L+EI G P S E
Sbjct 384 TAQEGAKFPIKWTAPEAIHFGVFTIKA--DVWSFGVLLMEIVTYGRVPYPGMSNPEVIRS 441
Query 827 YQRQHRLPEP-SCPQ--LATLTSQCLTYEPTQRPSF---RTILRDL 866
+ +R+P P +CP + ++C P +RP+F +++L D
Sbjct 442 LEHGYRMPCPETCPPELYNDIITECWRGRPEERPTFEFLQSVLEDF 487
>sp|Q06807|TIE2_BOVIN Angiopoietin-1 receptor OS=Bos taurus OX=9913
GN=TEK PE=2 SV=1
Length=1125
Score = 143 bits (361), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 102/309 (33%), Positives = 148/309 (48%), Gaps = 43/309 (14%)
Query 888 DPTVFHKRYLKKIR---DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
DPT++ I+ +GEG+FG+V DG A+K +K +
Sbjct 813 DPTIYPVLDWNDIKFQDVIGEGNFGQV--LKARIKKDGLRMDAAIKRMKEYASKDDHRDF 870
Query 945 KQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---------- 993
E+++L L +H +II G CE +G L L +EY P G+L D+L +
Sbjct 871 AGELEVLCKLGHHPNIINLLGACEHRG--YLYLAIEYAPHGNLLDFLRKSRVLETDPAFA 928
Query 994 -------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
++ QLL FA + GM YL + +IHRDLAARN+L+ + + KI DFGL++
Sbjct 929 IANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSR 988
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
G E Y + G PV W A E L + SDVWS+GV L+E+++
Sbjct 989 ----GQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVS---------- 1034
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L G MT L E L +G RL +P C EVY LM+ CW + RP+F ++
Sbjct 1035 ----LGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQIL 1090
Query 1167 PILKTVHEK 1175
L + E+
Sbjct 1091 VSLNRMLEE 1099
Score = 64.3 bits (155), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 79/335 (24%), Positives = 135/335 (40%), Gaps = 58/335 (17%)
Query 557 ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD- 615
+ L + R A+ +P L ++ + +++ + GQ + + + LR++ +
Sbjct 798 NSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKR 857
Query 616 -PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
E DD RD EL V+ K+ HH +L+ H +
Sbjct 858 MKEYASKDDH------RDFAGELEVLCKL---GHHP------NIINLLGACEHRGYLY-- 900
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRER--------GHVPMAWKMVVAQQL-------A 719
+ EY HG L +LR+ R + +QQL A
Sbjct 901 ----------LAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVA 950
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA-LSREERVERIP- 777
+ YL K +H ++ RNIL+ G + K++D G+ G + ++ + R+P
Sbjct 951 RGMDYLSQKQFIHRDLAARNILV-------GENYVAKIADFGLSRGQEVYVKKTMGRLPV 1003
Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836
W+A E L + +T D W +G L EI G P + +E + +RL +P
Sbjct 1004 RWMAIESL--NYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKP 1061
Query 837 -SC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+C ++ L QC +P +RPSF IL L R+
Sbjct 1062 LNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRM 1096
>sp|Q06806|TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mus
musculus OX=10090 GN=Tie1 PE=1 SV=3
Length=1134
Score = 143 bits (361), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 99/281 (35%), Positives = 134/281 (48%), Gaps = 40/281 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961
+GEG+FG+V DG A+K LK + E+++L L +H +II
Sbjct 841 IGEGNFGQVIRAMIK--KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIIN 898
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-----------GLA------QLLLFA 1004
G CE++G L + +EY P G+L D+L + + G A QLL FA
Sbjct 899 LLGACENRG--YLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFA 956
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
GM YL + +IHRDLAARNVL+ + KI DFGL++ G E Y + G P
Sbjct 957 SDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSR----GEEVYVKKTMGRLP 1012
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
V W A E L + SDVWSFGV L+E+++ L G MT L
Sbjct 1013 VRWMAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCGMTCAEL 1058
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
E L +G R+ +P C EVY LM+ CW RP F +
Sbjct 1059 YEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQI 1099
Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 71/332 (21%), Positives = 129/332 (39%), Gaps = 54/332 (16%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
+ L + R + P L+ L + + +++ + GQ R + + L++ +
Sbjct 809 SGTLTLTRRPKPQPEPLSYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKML 868
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
+ + D RD EL V+ K+ HH ++ + G C
Sbjct 869 KEYASEND----HRDFAGELEVLCKL---GHH------------------PNIINLLGAC 903
Query 678 VRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLASAL 722
+ EY +G L +LR+ R + + A A+ +
Sbjct 904 ENRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGM 963
Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP--WL 779
YL K +H ++ RN+L+ G + K++D G+ G + ++ + R+P W+
Sbjct 964 QYLSEKQFIHRDLAARNVLV-------GENLASKIADFGLSRGEEVYVKKTMGRLPVRWM 1016
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838
A E L + +T D W FG L EI G P + +E + +R+ +P +C
Sbjct 1017 AIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNC 1074
Query 839 -PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
++ L QC P +RP F I L R+
Sbjct 1075 DDEVYELMRQCWRDRPYERPPFAQIALQLGRM 1106
>sp|P21709|EPHA1_HUMAN Ephrin type-A receptor 1 OS=Homo sapiens
OX=9606 GN=EPHA1 PE=1 SV=4
Length=976
Score = 143 bits (360), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 88/266 (33%), Positives = 134/266 (50%), Gaps = 22/266 (8%)
Query 903 LGEGHFGKVSLYCYD-PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG FG+V P+ D + VA+K LK + +E I+ H HI+
Sbjct 630 IGEGEFGEVYRGTLRLPSQDC--KTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 687
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHY 1019
+G + K + ++ E++ G+L +L L QL+ Q I GM YL +Y
Sbjct 688 LEGVVTKR--KPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNY 745
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDLAARN+L++ + K+ DFGL + + + Y + G P+ W APE + F
Sbjct 746 VHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYET-QGGKIPIRWTAPEAIAHRIFT 804
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
ASDVWSFG+ ++E+L+ D G+M+ + + +E G RLP P
Sbjct 805 TASDVWSFGIVMWEVLSFGDK--------------PYGEMSNQEVMKSIEDGYRLPPPVD 850
Query 1140 CPCEVYHLMKNCWETEASFRPTFENL 1165
CP +Y LMKNCW + + RP F+ L
Sbjct 851 CPAPLYELMKNCWAYDRARRPHFQKL 876
Score = 101 bits (252), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 73/236 (31%), Positives = 114/236 (48%), Gaps = 15/236 (6%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F A++M Q SH H+ + GV + +++TE++E+G LD +LR + + +
Sbjct 670 FLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAM 729
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF--IKLSDPGVGLGALSREER 772
Q +AS ++YL N N VH ++ RNIL+ + L S F +L D G + E +
Sbjct 730 LQGIASGMNYLSNHNYVHRDLAARNILVNQ-NLCCKVSDFGLTRLLDDFDG----TYETQ 784
Query 773 VERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
+IP W APE + +TA D W FG + E+ G+ P S E +
Sbjct 785 GGKIPIRWTAPEAI--AHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDG 842
Query 831 HRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVLTVNP 882
+RLP P CP L L C Y+ +RP F+ + L +L PH+L + +P
Sbjct 843 YRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRTIANFDP 898
>sp|Q02763|TIE2_HUMAN Angiopoietin-1 receptor OS=Homo sapiens
OX=9606 GN=TEK PE=1 SV=2
Length=1124
Score = 143 bits (360), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 102/309 (33%), Positives = 148/309 (48%), Gaps = 43/309 (14%)
Query 888 DPTVFHKRYLKKIR---DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
DPT++ I+ +GEG+FG+V DG A+K +K +
Sbjct 812 DPTIYPVLDWNDIKFQDVIGEGNFGQV--LKARIKKDGLRMDAAIKRMKEYASKDDHRDF 869
Query 945 KQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---------- 993
E+++L L +H +II G CE +G L L +EY P G+L D+L +
Sbjct 870 AGELEVLCKLGHHPNIINLLGACEHRG--YLYLAIEYAPHGNLLDFLRKSRVLETDPAFA 927
Query 994 -------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
++ QLL FA + GM YL + +IHRDLAARN+L+ + + KI DFGL++
Sbjct 928 IANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSR 987
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
G E Y + G PV W A E L + SDVWS+GV L+E+++
Sbjct 988 ----GQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVS---------- 1033
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L G MT L E L +G RL +P C EVY LM+ CW + RP+F ++
Sbjct 1034 ----LGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQIL 1089
Query 1167 PILKTVHEK 1175
L + E+
Sbjct 1090 VSLNRMLEE 1098
Score = 63.5 bits (153), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 76/307 (25%), Positives = 125/307 (41%), Gaps = 51/307 (17%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEG-SGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
+D +I +G+G V + R++ +G D +M + RD EL V+ K
Sbjct 819 LDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCK 878
Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+ HH +L+ H + + EY HG L +LR+
Sbjct 879 L---GHHP------NIINLLGACEHRGYLY------------LAIEYAPHGNLLDFLRKS 917
Query 703 R--------GHVPMAWKMVVAQQL-------ASALSYLENKNLVHGNVCGRNILLARLGL 747
R + +QQL A + YL K +H ++ RNIL+
Sbjct 918 RVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILV----- 972
Query 748 AEGTSPFIKLSDPGVGLGA-LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATL 804
G + K++D G+ G + ++ + R+P W+A E L + +T D W +G L
Sbjct 973 --GENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESL--NYSVYTTNSDVWSYGVLL 1028
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEPTQRPSFRTI 862
EI G P + +E + +RL +P +C ++ L QC +P +RPSF I
Sbjct 1029 WEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQI 1088
Query 863 LRDLTRL 869
L L R+
Sbjct 1089 LVSLNRM 1095
>sp|Q10656|EGL15_CAEEL Myoblast growth factor receptor egl-15
OS=Caenorhabditis elegans OX=6239 GN=egl-15 PE=1 SV=1
Length=1040
Score = 143 bits (360), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 101/318 (32%), Positives = 151/318 (47%), Gaps = 53/318 (17%)
Query 887 SDPT-VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
SDP + L + LGEG FG+V Y T + VAVK LK +
Sbjct 629 SDPVWEVERSKLSLVHMLGEGAFGEVWKATYKETENNEI-AVAVKKLKMSAHEKELIDLV 687
Query 946 QEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----------- 993
E++ + + HE++++ GCC G L +V+E G+LRD+L H
Sbjct 688 SEMETFKVIGEHENVLRLIGCC--TGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSS 745
Query 994 ----------------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031
++ L+ FA Q+ +GM +L ++ IHRDLAARNVL+
Sbjct 746 QELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLV 805
Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091
+ ++KI DFGL++ V ++YYR R +G P+ W A E L + SDVWS+GV L
Sbjct 806 GDGHVLKISDFGLSRDV-HCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLL 864
Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
+E++T L G + + L L+ G R+ P CP EVYHLM +C
Sbjct 865 WEIMT--------------LGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEVYHLMCSC 910
Query 1152 WETEASFRPTFENLIPIL 1169
W + RP+F+ ++ L
Sbjct 911 WREKLEERPSFKTIVDYL 928
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 46/170 (27%), Positives = 77/170 (45%), Gaps = 23/170 (14%)
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
+R V AW Q+A +++L +K ++H ++ RN+L+ G +K+SD G
Sbjct 771 QRHLVQFAW------QVAQGMNFLASKKIIHRDLAARNVLV-------GDGHVLKISDFG 817
Query 762 VGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
+ + +R I W+A E L +N + D W +G L EI G P
Sbjct 818 LSRDVHCNDYYRKRGNGRLPIKWMALEAL--DSNVYTVESDVWSYGVLLWEIMTLGGTPY 875
Query 816 QSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTIL 863
+ + E + +R+ P CPQ + L C + +RPSF+TI+
Sbjct 876 PTIAMPELYANLKEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIV 925
>sp|O76997|TRK1_LYMST Putative neurotrophin receptor LTRK 1 OS=Lymnaea
stagnalis OX=6523 PE=2 SV=1
Length=794
Score = 142 bits (358), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 91/291 (31%), Positives = 141/291 (48%), Gaps = 37/291 (13%)
Query 900 IRDLGEGHFGKVSL-YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+R +GEG FG+V L C +VAVK LK C + +++E ++L T+ H +
Sbjct 507 MRVIGEGAFGRVFLGTCAHLIQKNEFAIVAVKTLKGSCSDSLKRDFEREAEMLATIEHAN 566
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA------------------QL 1000
I+ + G C + + ++ E++ G L YL H A QL
Sbjct 567 IVTFYGVCTESDQ--WMMIFEFMENGDLNKYLRMHGPDAAFLKDRDSMDSDEGQLTREQL 624
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+ QI M YL QH++HRDLA RN L+ D +VK+GDFG+++ V +YYRV
Sbjct 625 MKIVLQIASAMEYLALQHFVHRDLATRNCLVGCDLVVKLGDFGMSRDV-YTTDYYRVEGT 683
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
PV W PE + F SDVWSFGVTL+E+ T+ + P ++ +
Sbjct 684 AMLPVRWMPPESIIYRTFTTESDVWSFGVTLWEVFTY---GKQPWFEY-----------S 729
Query 1121 VLRLTELLERGERLPRPDK-CPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ E ++ L RP + C VY +M+ CW+ R T +++ +L+
Sbjct 730 NSEVIEHIKNSRTLKRPPRTCTDGVYRVMQGCWKPNPQDRLTMKDIAELLR 780
Score = 71.2 bits (173), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 57/221 (26%), Positives = 95/221 (43%), Gaps = 32/221 (14%)
Query 639 VVLKVLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V +K L S D + F A +++ + H ++ +GVC + +M+ E++E+G L+
Sbjct 535 VAVKTLKGSCSDSLKRDFEREAEMLATIEHANIVTFYGVCTESDQWMMIFEFMENGDLNK 594
Query 698 WLR----------------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
+LR + G + M + Q+ASA+ YL ++ VH ++ RN L
Sbjct 595 YLRMHGPDAAFLKDRDSMDSDEGQLTREQLMKIVLQIASAMEYLALQHFVHRDLATRNCL 654
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGANSLSTAM 795
+ G +KL D G+ + R E +P W+ PE + + +T
Sbjct 655 V-------GCDLVVKLGDFGMSRDVYTTDYYRVEGTAMLPVRWMPPESII--YRTFTTES 705
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836
D W FG TL E+ G+ P S SE + L P
Sbjct 706 DVWSFGVTLWEVFTYGKQPWFEYSNSEVIEHIKNSRTLKRP 746
>sp|Q9PVZ4|INSR_XENLA Insulin receptor OS=Xenopus laevis OX=8355
GN=insr PE=1 SV=1
Length=1362
Score = 143 bits (361), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 92/283 (33%), Positives = 147/283 (52%), Gaps = 29/283 (10%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+R+LG+G FG V G E+ VAVK + + R + E +++ H
Sbjct 1015 LRELGQGSFGMVYEGIAKDIIKGEPEVRVAVKTVNESASLRERIEFLNEASVMKAFNCHH 1074
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------PRHSIGLAQLLLFAQQI 1007
+++ G +G+ +L ++ME + G L+ YL R + L +++ A +I
Sbjct 1075 VVRLLGVVS-KGQPTL-VIMELMAHGDLKSYLRSLRPDAENNPGRLAPTLKEIIQMAAEI 1132
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+GMAYL+A+ ++HRDLAARN ++ +D VKIGDFG+ + + E +YYR G PV W
Sbjct 1133 SDGMAYLNAKKFVHRDLAARNCMVADDYAVKIGDFGMTRDIYET-DYYRKGGKGLLPVRW 1191
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
+PE LK+ F SDVWSFGV L+E+ + + G++ Q + +
Sbjct 1192 MSPESLKDGVFTAFSDVWSFGVVLWEITSLAEQPYQ---------GLSNEQ-----VLKF 1237
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ G L P+ CP ++ LM+ CW+ RPTF +I +LK
Sbjct 1238 VMDGGSLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLK 1280
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 77/298 (26%), Positives = 124/298 (42%), Gaps = 46/298 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V + +I L LGQG+ VYEG + G+PE +RV +K
Sbjct 1007 VPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPE-------------------VRVAVKT 1047
Query 644 LDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
++ S + F AS+M + H+ + GV +G +++ E + HG L +LR
Sbjct 1048 VNESASLRERIEFLNEASVMKAFNCHHVVRLLGVVSKGQPTLVIMELMAHGDLKSYLRSL 1107
Query 703 R-------GHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
R G + K ++ A +++ ++YL K VH ++ RN ++A
Sbjct 1108 RPDAENNPGRLAPTLKEIIQMAAEISDGMAYLNAKKFVHRDLAARNCMVA-------DDY 1160
Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+ D G+ + + + + W++PE L G + D W FG L EI
Sbjct 1161 AVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTAFSDVWSFGVVLWEI 1218
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
E P Q S + F L PE P+L +L C Y P RP+F I+
Sbjct 1219 TSLAEQPYQGLSNEQVLKFVMDGGSLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEII 1276
>sp|O15146|MUSK_HUMAN Muscle, skeletal receptor tyrosine-protein
kinase OS=Homo sapiens OX=9606 GN=MUSK PE=1 SV=1
Length=869
Score = 142 bits (358), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 90/318 (28%), Positives = 156/318 (49%), Gaps = 53/318 (17%)
Query 892 FHKRYLKKIRDLGEGHFGKV------SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
+ + ++ +RD+GEG FG+V L Y+P MVAVK LK + ++ ++
Sbjct 570 YPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFT-----MVAVKMLKEEASADMQADFQ 624
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------- 994
+E ++ + +I+K G C K + L+ EY+ G L ++L S
Sbjct 625 REAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSD 682
Query 995 --------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040
+ A+ L A+Q+ GMAYL + ++HRDLA RN L+ + +VKI
Sbjct 683 LSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIA 742
Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100
DFGL++ + +YY+ E+ P+ W PE + ++ SDVW++GV L+E+ ++
Sbjct 743 DFGLSRNIYSA-DYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSY--- 798
Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
G+A ++ + G L P+ CP E+Y+LM+ CW + RP
Sbjct 799 ------GLQPYYGMAHEEVIY-----YVRDGNILSCPENCPVELYNLMRLCWSKLPADRP 847
Query 1161 TFENLIPILKTVHEKYQG 1178
+F ++ IL+ + E+ +G
Sbjct 848 SFTSIHRILERMCERAEG 865
Score = 77.8 bits (190), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 67/263 (25%), Positives = 117/263 (44%), Gaps = 41/263 (16%)
Query 639 VVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V +K+L + + D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+
Sbjct 606 VAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNE 665
Query 698 WLRRERGH-----------------------VPMAWKMVVAQQLASALSYLENKNLVHGN 734
+LR H + A ++ +A+Q+A+ ++YL + VH +
Sbjct 666 FLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRD 725
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGA 788
+ RN L+ G + +K++D G+ S E I W+ PE +
Sbjct 726 LATRNCLV-------GENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESI--FY 776
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTS 846
N +T D W +G L EI G P + E ++ + + L P +CP +L L
Sbjct 777 NRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMR 836
Query 847 QCLTYEPTQRPSFRTILRDLTRL 869
C + P RPSF +I R L R+
Sbjct 837 LCWSKLPADRPSFTSIHRILERM 859
>sp|Q07E37|MET_NEONE Hepatocyte growth factor receptor OS=Neofelis
nebulosa OX=61452 GN=MET PE=3 SV=1
Length=1382
Score = 143 bits (360), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 95/284 (33%), Positives = 144/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T +D AVK+L S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348
Score = 60.8 bits (146), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1341
>sp|A0M8S8|MET_FELCA Hepatocyte growth factor receptor OS=Felis
catus OX=9685 GN=MET PE=3 SV=1
Length=1382
Score = 143 bits (360), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 95/284 (33%), Positives = 144/284 (51%), Gaps = 27/284 (10%)
Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G GHFG V Y T +D AVK+L S + E I++ H ++
Sbjct 1085 IGRGHFGCV----YHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++
Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075
++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+
Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF SDVWSFGV L+EL+T +PP + +T L +G RL
Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348
Score = 60.8 bits (146), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++
Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183
Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+A + YL +K VH ++ RN +L +K++D G+ +E
Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236
Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++P W+A E L +T D W FG L E+ G P + +
Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + RL +P CP L + +C + RPSF ++ ++ +
Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1341
>sp|O45539|SRC2_CAEEL Tyrosine protein-kinase src-2 OS=Caenorhabditis
elegans OX=6239 GN=src-2 PE=1 SV=2
Length=507
Score = 138 bits (348), Expect = 5e-33, Method: Compositional matrix adjust.
Identities = 100/307 (33%), Positives = 149/307 (49%), Gaps = 42/307 (14%)
Query 875 ADVLTVNPDSP-----ASDPTVF--------HKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
AD L VN +P A T F +R ++ IR +G G FG+V ++
Sbjct 205 ADGLCVNLGAPCAKSEAPQTTTFTYDDQWEVDRRSVRLIRQIGAGQFGEVWEGRWN---- 260
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK-YKGCCEDQGEKSLQLVMEY 980
VAVK LKA G + + E I++ L H ++ Y C D+ L++
Sbjct 261 -VNVPVAVKKLKA--GTADPTDFLAEAQIMKKLRHPKLLSLYAVCTRDEP----ILIVTE 313
Query 981 VPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
+ +L +L R + QL+ + Q+ GMAYL ++IHRDLAARN+L++N VK
Sbjct 314 LMQENLLTFLQRRGRQCQMPQLVEISAQVAAGMAYLEEMNFIHRDLAARNILINNSLSVK 373
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
I DFGLA+ + + +E Y R P+ W APE +F SDVWSFG+ L E++T
Sbjct 374 IADFGLARILMKENE-YEARTGARFPIKWTAPEAANYNRFTTKSDVWSFGILLTEIVT-- 430
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
+ MT + + ++ G R+P P CP +Y +M+ CW ++
Sbjct 431 ------------FGRLPYPGMTNAEVLQQVDAGYRMPCPAGCPVTLYDIMQQCWRSDPDK 478
Query 1159 RPTFENL 1165
RPTFE L
Sbjct 479 RPTFETL 485
Score = 99.8 bits (247), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 107/415 (26%), Positives = 167/415 (40%), Gaps = 75/415 (18%)
Query 467 EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSV 526
E G +L+ S S + L L+V + D ++ R+R+ G F+ R F ++
Sbjct 144 EHGAFLVRDSESRQHDLSLSVREN----DSVKHYRIRQL---DHGGYFIARR--RPFATL 194
Query 527 RELGAALQGCLLRAGDD-CFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVD 585
+L A Q R D C +L C +P+T + VD
Sbjct 195 HDLIAHYQ----READGLCVNLGAPC--------------AKSEAPQTTTFTYDDQWEVD 236
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ + + +G G V+EGR V VP V +K L
Sbjct 237 RRSVRLIRQIGAGQFGEVWEGRWNVN----------------VP---------VAVKKLK 271
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
D F A +M ++ H L ++ VC R ++VTE ++ L RR R
Sbjct 272 AGTAD-PTDFLAEAQIMKKLRHPKLLSLYAVCTRDEPILIVTELMQENLLTFLQRRGR-Q 329
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
M + ++ Q+A+ ++YLE N +H ++ RNIL+ S +K++D G+
Sbjct 330 CQMPQLVEISAQVAAGMAYLEEMNFIHRDLAARNILI-------NNSLSVKIADFGLARI 382
Query 766 ALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ E R I W APE N +T D W FG L EI G P +
Sbjct 383 LMKENEYEARTGARFPIKWTAPEA--ANYNRFTTKSDVWSFGILLTEIVTFGRLPYPGMT 440
Query 820 PSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI---LRDLTRL 869
+E +R+P P+ CP L + QC +P +RP+F T+ L DL L
Sbjct 441 NAEVLQQVDAGYRMPCPAGCPVTLYDIMQQCWRSDPDKRPTFETLQWKLEDLFNL 495
>sp|Q95ZV7|DDRB_CAEEL Discoidin domain-containing receptor tyrosine
kinase B OS=Caenorhabditis elegans OX=6239 GN=ddr-2 PE=1
SV=1
Length=797
Score = 141 bits (356), Expect = 5e-33, Method: Compositional matrix adjust.
Identities = 92/272 (34%), Positives = 146/272 (54%), Gaps = 26/272 (10%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL----KADCGPQHRSGWKQEIDILRTLY 955
+ +G+G FG+V L + VAVK L +AD HR EI +L +L
Sbjct 530 VSRIGQGEFGEVDLCQLE------NRKVAVKKLHGISQADEFSFHR-----EIRVLGSLK 578
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYL 1014
H ++++ G C Q K + +MEY+ G L+ Y+ ++ +I +Q + Q+ G+AYL
Sbjct 579 HPNVVEVVGVCTIQ--KPILCIMEYMENGDLKSYILKNPTIQTSQCISICTQLAAGLAYL 636
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+ +++HRD+AARN L+D + VKI DFG+A+++ EYY+V P+ W A E L
Sbjct 637 ESCNFVHRDIAARNCLVDGEGNVKIADFGMARSL-YSQEYYKVEGKFVLPIRWMAWEALL 695
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF ASDVW FGVT++E+ + C +++ Q + L ++L
Sbjct 696 LGKFSTASDVWGFGVTMWEIFSLCSEKPYSDMTDDDVVENLQSMSSTGSLKQVLS----- 750
Query 1135 PRPDKCPCEVYH-LMKNCWETEASFRPTFENL 1165
RP CP ++Y+ + CW E+S RP+FEN+
Sbjct 751 -RPRMCPSKLYNEQILPCWNYESSRRPSFENV 781
Score = 77.4 bits (189), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 71/257 (28%), Positives = 115/257 (45%), Gaps = 34/257 (13%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L +F+ ++ + H ++ V GVC + + EY+E+G L
Sbjct 550 KVAVKKLHGISQADEFSFHREIRVLGSLKHPNVVEVVGVCTIQKPILCIMEYMENGDLKS 609
Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
++ + + + + + QLA+ L+YLE+ N VH ++ RN L+ EG +K+
Sbjct 610 YILKNPT-IQTSQCISICTQLAAGLAYLESCNFVHRDIAARNCLVD----GEGN---VKI 661
Query 758 SDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI-CFD 810
+D G+ S+E + V I W+A E L G STA D WGFG T+ EI
Sbjct 662 ADFGMARSLYSQEYYKVEGKFVLPIRWMAWEALLLG--KFSTASDVWGFGVTMWEIFSLC 719
Query 811 GEAPLQSRSPSEKEHFYQR-------QHRLPEPS-CPQLATLTSQ----CLTYEPTQRPS 858
E P + + Q + L P CP + L ++ C YE ++RPS
Sbjct 720 SEKPYSDMTDDDVVENLQSMSSTGSLKQVLSRPRMCP--SKLYNEQILPCWNYESSRRPS 777
Query 859 FRTI---LRDLTRLQPH 872
F + L+ L PH
Sbjct 778 FENVHLHLQSLVHTSPH 794
>sp|Q4H3K6|FGFR_CIOIN Fibroblast growth factor receptor OS=Ciona
intestinalis OX=7719 GN=FGFR PE=2 SV=1
Length=747
Score = 140 bits (354), Expect = 7e-33, Method: Compositional matrix adjust.
Identities = 98/291 (34%), Positives = 139/291 (48%), Gaps = 41/291 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMV--AVKALKADCGPQHRSGWKQEIDILRTL-YHEHI 959
+ EG FG+V G E V AVK LK+ + E+D ++ + H++I
Sbjct 383 IDEGFFGQVFRADLIRCAGGRKEKVDAAVKMLKSTRTEKDMLDLLTEMDQMKRVGKHKNI 442
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------------------IGLA 998
+ G C G L LV EY G+LRDYL R+ + L
Sbjct 443 VNLLGVCTQNG--ILWLVTEYAQKGNLRDYLRRNRPSELQYELSTPDSPAPPRDEPLTLR 500
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
L+ + Q+ GM YL + IHRDLAARNVL+ ND ++KI DFGLA+ + ++YYR
Sbjct 501 ALMSASHQVARGMEYLSQKKCIHRDLAARNVLVANDFVMKIADFGLARDI-RSNDYYRKE 559
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
G P W A E + + F +A+DVWSFG+ L+E+ + S P K +L+
Sbjct 560 TRGHLPYKWMALEAMTDNMFTHATDVWSFGILLWEIFS-LGGSPYPGVKTHDLV------ 612
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
L G+RL +P E+Y LM++CWE RP F L+ L
Sbjct 613 -------RFLRNGDRLEQPQFASSELYRLMRDCWEESPRRRPQFRQLVEDL 656
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 67/266 (25%), Positives = 111/266 (42%), Gaps = 38/266 (14%)
Query 633 RGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
R +++ +K+L + D+ E + H ++ + GVC + +VTEY
Sbjct 403 RKEKVDAAVKMLKSTRTEKDMLDLLTEMDQMKRVGKHKNIVNLLGVCTQNGILWLVTEYA 462
Query 691 EHGPLDVWLRRER-----------------GHVPMAWK--MVVAQQLASALSYLENKNLV 731
+ G L +LRR R P+ + M + Q+A + YL K +
Sbjct 463 QKGNLRDYLRRNRPSELQYELSTPDSPAPPRDEPLTLRALMSASHQVARGMEYLSQKKCI 522
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLP 785
H ++ RN+L+A +K++D G+ S R+E +P W+A E +
Sbjct 523 HRDLAARNVLVA-------NDFVMKIADFGLARDIRSNDYYRKETRGHLPYKWMALEAMT 575
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLAT 843
N + A D W FG L EI G +P + F + RL +P + +L
Sbjct 576 D--NMFTHATDVWSFGILLWEIFSLGGSPYPGVKTHDLVRFLRNGDRLEQPQFASSELYR 633
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869
L C P +RP FR ++ DL R+
Sbjct 634 LMRDCWEESPRRRPQFRQLVEDLDRM 659
>sp|F1LM93|YES_RAT Tyrosine-protein kinase Yes OS=Rattus norvegicus
OX=10116 GN=Yes1 PE=1 SV=1
Length=541
Score = 138 bits (348), Expect = 8e-33, Method: Compositional matrix adjust.
Identities = 104/334 (31%), Positives = 155/334 (46%), Gaps = 42/334 (13%)
Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVL---------TVNPDSP--ASDPTVFHKRYLKK 899
Y T R F T+ + + H AD L TV P + A D + L+
Sbjct 220 YYITTRAQFDTLQKLVKHYTEH--ADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRL 277
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG+V + ++ T VA+K LK G + QE I++ L H+ +
Sbjct 278 EVKLGQGCFGEVWMGTWNGTTK-----VAIKTLKP--GTMMPEAFLQEAQIMKKLRHDKL 330
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA 1016
+ E+ + +V E++ G L D+L + L QL+ A QI +GMAY+
Sbjct 331 VPLYAVVS---EEPIYIVTEFMSKGILLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIER 387
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+YIHRDL A N+L+ + + KI DFGLA+ + + Y R+ P+ W APE
Sbjct 388 MNYIHRDLRAANILVGENLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYG 445
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+F SDVWSFG+ EL+T + M + E +ERG R+P
Sbjct 446 RFTIKSDVWSFGILQTELVTKGR--------------VPYPGMVNREVLEQVERGYRMPC 491
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
P CP ++ LM CW+ + RPTFE + L+
Sbjct 492 PQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 525
Score = 72.8 bits (177), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 63/233 (27%), Positives = 106/233 (45%), Gaps = 19/233 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P + AF + A +M ++ H L ++ V P I VTE++ G L
Sbjct 299 KVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEFMSKGILLD 356
Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G ++ + + +A Q+A ++Y+E N +H ++ NIL+ G + K
Sbjct 357 FLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILV-------GENLVCK 409
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG E+ G
Sbjct 410 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILQTELVTKG 467
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
P E +R +R+P P CP+ L L + C +P +RP+F I
Sbjct 468 RVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYI 520
>sp|Q95YM9|FGFR_HALRO Fibroblast growth factor receptor OS=Halocynthia
roretzi OX=7729 GN=FGFR PE=2 SV=1
Length=763
Score = 140 bits (354), Expect = 9e-33, Method: Compositional matrix adjust.
Identities = 101/298 (34%), Positives = 143/298 (48%), Gaps = 48/298 (16%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGE--MVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956
+ L EG FG+V N+ E + AVK LK + + E+D ++ + H
Sbjct 385 VERLDEGFFGQVFKADLVTCNNTRKEKMVCAVKMLKGNRNEKDVLDLLTEMDQMKRVGKH 444
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR------------------------ 992
++II G C G L LV+EY G+LRDYL R
Sbjct 445 KNIINLLGVCTQNG--PLWLVIEYAAQGNLRDYLRRNRPQNTLCNLVLPSEGRNPDDELP 502
Query 993 --HSIGLAQ--LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
H L Q ++ FA Q+ G+ +L + IHRDLAARNVL+ + ++KI DFGLA+ +
Sbjct 503 VPHGDTLTQKDIVSFAFQVARGLEFLAQKKCIHRDLAARNVLVTEELVMKIADFGLARDI 562
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
+YYR G P W A E + + F +A+DVWSFGV L+E+ + S P K
Sbjct 563 -RSCDYYRKHTRGHLPYKWMALEAMSDNIFTHATDVWSFGVLLWEIFSLA-GSPYPGIKT 620
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
EL+ + L GERL +P E+Y LM++CWE + S RP F L+
Sbjct 621 HELV-------------KFLRSGERLDKPQYASQEMYRLMRDCWEEDPSKRPNFRTLV 665
Score = 69.3 bits (168), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 69/287 (24%), Positives = 118/287 (41%), Gaps = 45/287 (16%)
Query 619 GKMDDEDPLVPGRDRGQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676
G++ D + R +++ +K+L + + D+ E + H ++ + GV
Sbjct 394 GQVFKADLVTCNNTRKEKMVCAVKMLKGNRNEKDVLDLLTEMDQMKRVGKHKNIINLLGV 453
Query 677 CVRGPENIMVTEYVEHGPLDVWLRRER-------------GHVP-----------MAWKM 712
C + +V EY G L +LRR R G P + K
Sbjct 454 CTQNGPLWLVIEYAAQGNLRDYLRRNRPQNTLCNLVLPSEGRNPDDELPVPHGDTLTQKD 513
Query 713 VV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS-- 768
+V A Q+A L +L K +H ++ RN+L+ +K++D G+ S
Sbjct 514 IVSFAFQVARGLEFLAQKKCIHRDLAARNVLVTE-------ELVMKIADFGLARDIRSCD 566
Query 769 --REERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
R+ +P W+A E + N + A D W FG L EI +P E
Sbjct 567 YYRKHTRGHLPYKWMALEAM--SDNIFTHATDVWSFGVLLWEIFSLAGSPYPGIKTHELV 624
Query 825 HFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
F + RL +P + ++ L C +P++RP+FRT++ DL R+
Sbjct 625 KFLRSGERLDKPQYASQEMYRLMRDCWEEDPSKRPNFRTLVEDLDRM 671
>sp|Q12866|MERTK_HUMAN Tyrosine-protein kinase Mer OS=Homo sapiens
OX=9606 GN=MERTK PE=1 SV=2
Length=999
Score = 141 bits (356), Expect = 9e-33, Method: Compositional matrix adjust.
Identities = 97/288 (34%), Positives = 138/288 (48%), Gaps = 29/288 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEI 948
V + L + LGEG FG V + DGT VAVK +K D Q + E
Sbjct 580 VVIDRNLLILGKILGEGEFGSV-MEGNLKQEDGTSLKVAVKTMKLDNSSQREIEEFLSEA 638
Query 949 DILRTLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGSLRDYL--------PRHSIGL 997
++ H ++I+ G C QG +++ ++ G L YL P+H I L
Sbjct 639 ACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKH-IPL 697
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
LL F I GM YL ++++HRDLAARN +L +D V + DFGL+K + G +YYR
Sbjct 698 QTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQ 756
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
PV W A E L + + SDVW+FGVT++E+ T G+
Sbjct 757 GRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATR---------GMTPYPGVQNH 807
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+M + L G RL +P+ C E+Y +M +CW T+ RPTF L
Sbjct 808 EM-----YDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVL 850
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 81/306 (26%), Positives = 129/306 (42%), Gaps = 51/306 (17%)
Query 606 GRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKV--LDPSHHDIALAFYETASLM 662
G++ EG G EG + ED G L+V +K LD S F A+ M
Sbjct 590 GKILGEGEFGSVMEGNLKQED--------GTSLKVAVKTMKLDNSSQREIEEFLSEAACM 641
Query 663 SQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDVWL---RRERG--HVPMAWKM 712
SH ++ + GVC+ P+ +++ ++++G L +L R E G H+P+ +
Sbjct 642 KDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKHIPLQTLL 701
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPGVGL 764
+A + YL N+N +H ++ RN +L A GL++ +
Sbjct 702 KFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSK-----------KIYS 750
Query 765 GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
G R+ R+ ++P W+A E L ++ D W FG T+ EI G P E
Sbjct 751 GDYYRQGRIAKMPVKWIAIESL--ADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHE 808
Query 823 KEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL-----QPHNLA 875
+ HRL PE +L + C +P RP+F + L +L N A
Sbjct 809 MYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESLPDVRNQA 868
Query 876 DVLTVN 881
DV+ VN
Sbjct 869 DVIYVN 874
>sp|O42422|EPHA7_CHICK Ephrin type-A receptor 7 OS=Gallus gallus
OX=9031 GN=EPHA7 PE=2 SV=1
Length=993
Score = 141 bits (356), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 88/276 (32%), Positives = 142/276 (51%), Gaps = 21/276 (8%)
Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
+K R +G G FG+V S P VA+K LK + R + E I+
Sbjct 628 IKIERVIGAGEFGEVCSGRLKLPGKRDVA--VAIKTLKVGYTEKQRRDFLCEASIMGQFD 685
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAY 1013
H +++ +G K + +V+EY+ G+L +L +H + QL+ + I GM Y
Sbjct 686 HPNVVHLEGVVTRG--KPVMIVIEYMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRY 743
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
L Y+HRDLAARN+L++++ + K+ DFGL++ + + E G PV W APE +
Sbjct 744 LADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAI 803
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF ASDVWS+G+ ++E++++ + P M+ + + +E G R
Sbjct 804 QYRKFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMSNQDVIKAIEEGYR 849
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
LP P CP ++ LM +CW+ E RP FE ++ IL
Sbjct 850 LPAPMDCPAGLHQLMLDCWQKERGERPKFEQIVGIL 885
Score = 89.7 bits (221), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 83/294 (28%), Positives = 135/294 (46%), Gaps = 28/294 (10%)
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSH 667
RV G+G E G++ +PG+ +++ V +K L + + F AS+M Q H
Sbjct 632 RVIGAG--EFGEVCSGRLKLPGK---RDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDH 686
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
++ + GV RG ++V EY+E+G LD +LR+ G + + + + +A+ + YL +
Sbjct 687 PNVVHLEGVVTRGKPVMIVIEYMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLAD 746
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIP--WLA 780
VH ++ RNIL+ ++ K+SD G+ E V +IP W A
Sbjct 747 MGYVHRDLAARNILV-------NSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTA 799
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP 839
PE + ++A D W +G + E+ GE P S + + +RLP P CP
Sbjct 800 PEAIQ--YRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCP 857
Query 840 Q-LATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVLTV--NPDSPASD 888
L L C E +RP F I+ L ++ P++L L P SP D
Sbjct 858 AGLHQLMLDCWQKERGERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLD 911
>sp|O09127|EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus musculus
OX=10090 GN=Epha8 PE=1 SV=2
Length=1004
Score = 141 bits (355), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 90/264 (34%), Positives = 134/264 (51%), Gaps = 19/264 (7%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VA+KALKA + R + E I+ H +II+ +G +G ++ +V EY+ GSL
Sbjct 663 VAIKALKAGYTERQRQDFLSEAAIMGQFDHPNIIRLEGVVT-RGRLAM-IVTEYMENGSL 720
Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L H + QL+ + + GM YL YIHRDLAARNVL+D + K+ DFGL
Sbjct 721 DAFLRTHDGQFTIVQLVGMLRGVGAGMRYLSDLGYIHRDLAARNVLVDGRLVCKVSDFGL 780
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
++A+ + E G P+ W APE + F ASDVWSFGV ++E+L + +
Sbjct 781 SRALEDDPEAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERP--- 837
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
MT + +E G RLP P CP ++ LM +CW + + RP F +
Sbjct 838 -----------YWNMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFAH 886
Query 1165 LIPILKT-VHEKYQGQAPSVFSVC 1187
++ +L VH +A + S C
Sbjct 887 VVSVLDALVHSPESLRATATVSRC 910
Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 86/330 (26%), Positives = 139/330 (42%), Gaps = 54/330 (16%)
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
R R+ R + S++ ++ +G G V GRL+V G D
Sbjct 620 RAGRSFTREIEASRIHIEKI----------IGSGESGEVCYGRLQVPGQRD--------- 660
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPEN 683
VP V +K L + + F A++M Q H ++ + GV RG
Sbjct 661 ---VP---------VAIKALKAGYTERQRQDFLSEAAIMGQFDHPNIIRLEGVVTRGRLA 708
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL- 742
++VTEY+E+G LD +LR G + + + + + + + YL + +H ++ RN+L+
Sbjct 709 MIVTEYMENGSLDAFLRTHDGQFTIVQLVGMLRGVGAGMRYLSDLGYIHRDLAARNVLVD 768
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIP--WLAPECLPGGANSLSTAM 795
RL K+SD G+ E +IP W APE + + S+A
Sbjct 769 GRL--------VCKVSDFGLSRALEDDPEAAYTTAGGKIPIRWTAPEAI--AFRTFSSAS 818
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEP 853
D W FG + E+ GE P + + + + +RLP P CP+ L L C +
Sbjct 819 DVWSFGVVMWEVLAYGERPYWNMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDR 878
Query 854 TQRPSFRTILRDLTRL--QPHNLADVLTVN 881
QRP F ++ L L P +L TV+
Sbjct 879 AQRPRFAHVVSVLDALVHSPESLRATATVS 908
>sp|P25020|SRC_RSVH1 Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus (strain H-19) OX=11887 GN=V-SRC
PE=1 SV=3
Length=526
Score = 137 bits (346), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 96/301 (32%), Positives = 147/301 (49%), Gaps = 34/301 (11%)
Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
H L +V T P + A D + L+ LG+G FG+V + ++ T VA
Sbjct 239 HRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEAKLGQGCFGEVWMGTWNGTT-----RVA 293
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL D
Sbjct 294 IKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVIEYMSKGSLLD 348
Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 349 FL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ER R+P P +CP ++ LM CW + RPTF+
Sbjct 461 ---------VPYPGMVNREVLDQVERAYRMPCPPECPESLHDLMCQCWRKDPEERPTFKY 511
Query 1165 L 1165
L
Sbjct 512 L 512
Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 69/237 (29%), Positives = 109/237 (46%), Gaps = 19/237 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +K L P AF + A +M ++ H L ++ V P I++ EY+ G L
Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVI-EYMSKGSLLD 348
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K
Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866
P E +R +R+P P CP+ L L QC +P +RP+F+ + L
Sbjct 460 RVPYPGMVNREVLDQVERAYRMPCPPECPESLHDLMCQCWRKDPEERPTFKYLQAQL 516
>sp|P35590|TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 OS=Homo
sapiens OX=9606 GN=TIE1 PE=1 SV=1
Length=1138
Score = 141 bits (356), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 98/281 (35%), Positives = 134/281 (48%), Gaps = 40/281 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961
+GEG+FG+V DG A+K LK + E+++L L +H +II
Sbjct 845 IGEGNFGQVIRAMIK--KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIIN 902
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-----------GLA------QLLLFA 1004
G C+++G L + +EY P G+L D+L + + G A QLL FA
Sbjct 903 LLGACKNRG--YLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFA 960
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
GM YL + +IHRDLAARNVL+ + KI DFGL++ G E Y + G P
Sbjct 961 SDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSR----GEEVYVKKTMGRLP 1016
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
V W A E L + SDVWSFGV L+E+++ L G MT L
Sbjct 1017 VRWMAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCGMTCAEL 1062
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
E L +G R+ +P C EVY LM+ CW RP F +
Sbjct 1063 YEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQI 1103
Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 71/332 (21%), Positives = 129/332 (39%), Gaps = 54/332 (16%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
+ L + R + P L+ L + + +++ + GQ R + + L++ +
Sbjct 813 SGTLTLTRRPKLQPEPLSYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKML 872
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
+ + D RD EL V+ K+ HH ++ + G C
Sbjct 873 KEYASEND----HRDFAGELEVLCKL---GHH------------------PNIINLLGAC 907
Query 678 VRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLASAL 722
+ EY +G L +LR+ R + + A A+ +
Sbjct 908 KNRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGM 967
Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP--WL 779
YL K +H ++ RN+L+ G + K++D G+ G + ++ + R+P W+
Sbjct 968 QYLSEKQFIHRDLAARNVLV-------GENLASKIADFGLSRGEEVYVKKTMGRLPVRWM 1020
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838
A E L + +T D W FG L EI G P + +E + +R+ +P +C
Sbjct 1021 AIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNC 1078
Query 839 -PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
++ L QC P +RP F I L R+
Sbjct 1079 DDEVYELMRQCWRDRPYERPPFAQIALQLGRM 1110
>sp|P00528|SRC64_DROME Tyrosine-protein kinase Src64B OS=Drosophila
melanogaster OX=7227 GN=Src64B PE=1 SV=3
Length=552
Score = 138 bits (347), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 93/275 (34%), Positives = 137/275 (50%), Gaps = 32/275 (12%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
++ +R LG G+FG+V + + D VAVK L+ G + + QE I++ H
Sbjct 284 IQLLRKLGRGNFGEVFYGKWRNSID-----VAVKTLRE--GTMSTAAFLQEAAIMKKFRH 336
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMA 1012
++ C E+ + +V EY+ GSL D+L R G L+ A Q+ GM
Sbjct 337 NRLVALYAVCSQ--EEPIYIVQEYMSKGSLLDFL-REGDGRYLHFEDLIYIATQVASGME 393
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
YL ++ IHRDLAARNVL+ + + KI DFGLA+ + + + Y ++ PV W APE
Sbjct 394 YLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIAD--DEYCPKQGSRFPVKWTAPEA 451
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ KF SDVWS+G+ L EL T+ + M + E +ERG
Sbjct 452 IIYGKFSIKSDVWSYGILLMELFTYGQ--------------VPYPGMHSREVIENIERGF 497
Query 1133 RLPRPDK--CPCEVYHLMKNCWETEASFRPTFENL 1165
R+P+P P +Y L+ CW+ RPTFE L
Sbjct 498 RMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFL 532
Score = 89.0 bits (219), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 100/402 (25%), Positives = 161/402 (40%), Gaps = 67/402 (17%)
Query 469 GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRE 528
G +L+ S +P L+V DG + ++ + I+ D ++FPS++
Sbjct 184 GTFLVRPSEHNPNGYSLSVKDWE---DG-RGYHVKHYRIKPLDNGGYYIATNQTFPSLQA 239
Query 529 LGAALQGCLLRAGDDCFSLRRCC-LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587
L A L C L R C PQP +R PR+
Sbjct 240 LVMAYSKNALGL---CHILSRPCPKPQPQMWDLGPELRDKYEIPRS-------------- 282
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
EI L LG+G V+ G+ R + V +K L
Sbjct 283 EIQLLRKLGRGNFGEVFYGKWR-------------------------NSIDVAVKTLREG 317
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HV 706
A AF + A++M + H L ++ VC + +V EY+ G L +LR G ++
Sbjct 318 TMSTA-AFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYL 376
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ +A Q+AS + YLE+K L+H ++ RN+L+ +A K+ D G+
Sbjct 377 HFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVA-------KICDFGLARVI 429
Query 767 LSRE---ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
E ++ R P W APE + G S+ + D W +G L+E+ G+ P
Sbjct 430 ADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKS--DVWSYGILLMELFTYGQVPYPGMHSR 487
Query 822 EKEHFYQRQHRLPEPSC----PQLATLTSQCLTYEPTQRPSF 859
E +R R+P+P+ + L QC P +RP+F
Sbjct 488 EVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTF 529
>sp|O73798|IGF1R_XENLA Insulin-like growth factor 1 receptor OS=Xenopus
laevis OX=8355 GN=igf1r PE=1 SV=1
Length=1358
Score = 141 bits (356), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 92/282 (33%), Positives = 143/282 (51%), Gaps = 29/282 (10%)
Query 901 RDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
R+LG+G FG V D VA+K + + R + E +++ H+
Sbjct 999 RELGQGSFGMVYEGIAKGVVKDEAETKVAIKTVNEAASMRERIEFLNEASVMKEFNCHHV 1058
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------PRHSIGLAQLLLFAQQIC 1008
++ G QG+ +L ++ME + G L+ YL + + L +++ A +I
Sbjct 1059 VRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSLRPDTESNSGQPTPSLKKMIQMAGEIA 1116
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+GM+YL+A ++HRDLAARN ++ D VKIGDFG+ + + E +YYR G PV W
Sbjct 1117 DGMSYLNANKFVHRDLAARNCMVTEDFTVKIGDFGMTRDIYET-DYYRKGGKGLLPVRWM 1175
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
+PE LK+ F SDVWSFGV L+E+ T + G++ Q VLR +
Sbjct 1176 SPESLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQ---------GMSNEQ--VLR---FV 1221
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
G L +PD CP ++ LM+ CW+ RP+F +I +K
Sbjct 1222 MEGGLLEKPDNCPDMLFELMRMCWQFNPKMRPSFLEIISSIK 1263
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 79/302 (26%), Positives = 127/302 (42%), Gaps = 48/302 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +++IT LGQG+ VYEG + G + DE E +V +K
Sbjct 990 VPREKITMNRELGQGSFGMVYEGIAK---------GVVKDE----------AETKVAIKT 1030
Query 644 LD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
++ + + F AS+M + + H+ + GV +G +++ E + G L +LR
Sbjct 1031 VNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSL 1090
Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
R P KM+ +A ++A +SYL VH ++ RN ++ T
Sbjct 1091 RPDTESNSGQPTPSLKKMIQMAGEIADGMSYLNANKFVHRDLAARNCMV--------TED 1142
Query 754 F-IKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
F +K+ D G+ + + + + W++PE L G +T D W FG L E
Sbjct 1143 FTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTNSDVWSFGVVLWE 1200
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILR 864
I E P Q S + F L +P +CP L L C + P RPSF I+
Sbjct 1201 IATLAEQPYQGMSNEQVLRFVMEGGLLEKPDNCPDMLFELMRMCWQFNPKMRPSFLEIIS 1260
Query 865 DL 866
+
Sbjct 1261 SI 1262
>sp|Q63474|DDR1_RAT Epithelial discoidin domain-containing receptor
1 OS=Rattus norvegicus OX=10116 GN=Ddr1 PE=2 SV=1
Length=910
Score = 140 bits (354), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 99/309 (32%), Positives = 141/309 (46%), Gaps = 47/309 (15%)
Query 892 FHKRYLKKIRDLGEGHFGKVSL-YCYDPTNDGTGE-----------MVAVKALKADCGPQ 939
F + L+ LGEG FG+V L DP + T + +VAVK L+ D
Sbjct 602 FPRSRLRFKEKLGEGQFGEVHLCEVEDPQDLVTSDFPISVQKGHPLLVAVKILRPDATKN 661
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------ 993
R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L H
Sbjct 662 ARNDFLKEVKIMSRLKDLNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSAHQLENKV 719
Query 994 --------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
+I LL QI GM YL +++HRDLA RN L+ + +KI
Sbjct 720 TQGLPGDRESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKI 779
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+L C
Sbjct 780 ADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCR 838
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER---LPRPDKCPCEVYHLMKNCWETEA 1156
S + G + + E R L RP CP +Y LM CW E
Sbjct 839 S---------QPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQTLYELMLRCWSREP 889
Query 1157 SFRPTFENL 1165
RP F L
Sbjct 890 EQRPPFSQL 898
Score = 80.1 bits (196), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 77/270 (29%), Positives = 122/270 (45%), Gaps = 44/270 (16%)
Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+G L V +K+L P A F + +MS++ ++ + GVCV+ M+T+Y+E
Sbjct 643 KGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDLNIIRLLGVCVQDDPLCMITDYME 702
Query 692 HGPLDVWLR---------------RERGHVP-MAWKMV--VAQQLASALSYLENKNLVHG 733
+G L+ +L RE P +++ M+ V Q+AS + YL N VH
Sbjct 703 NGDLNQFLSAHQLENKVTQGLPGDRESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHR 762
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGG 787
++ RN L+ G + IK++D G+ + + V I W+A EC+ G
Sbjct 763 DLATRNCLV-------GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG 815
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-----EHFYQRQHRLP----EPSC 838
+TA D W FG TL E+ + + E+ F++ Q R P+C
Sbjct 816 --KFTTASDVWAFGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPAC 873
Query 839 PQ-LATLTSQCLTYEPTQRPSFRTILRDLT 867
PQ L L +C + EP QRP F + R L
Sbjct 874 PQTLYELMLRCWSREPEQRPPFSQLHRFLA 903
>sp|P08069|IGF1R_HUMAN Insulin-like growth factor 1 receptor OS=Homo
sapiens OX=9606 GN=IGF1R PE=1 SV=1
Length=1367
Score = 141 bits (356), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 95/286 (33%), Positives = 146/286 (51%), Gaps = 37/286 (13%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGE-----MVAVKALKADCGPQHRSGWKQEIDILRTLY 955
R+LG+G FG V Y+ G + VA+K + + R + E +++
Sbjct 1003 RELGQGSFGMV----YEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFN 1058
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIG-------LAQLLLFA 1004
H+++ G QG+ +L ++ME + G L+ YL P L++++ A
Sbjct 1059 CHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMA 1116
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+I +GMAYL+A ++HRDLAARN ++ D VKIGDFG+ + + E +YYR G P
Sbjct 1117 GEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYE-TDYYRKGGKGLLP 1175
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
V W +PE LK+ F SDVWSFGV L+E+ T + G++ Q VLR
Sbjct 1176 VRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQ---------GLSNEQ--VLR- 1223
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ G L +PD CP ++ LM+ CW+ RP+F +I +K
Sbjct 1224 --FVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK 1267
Score = 84.3 bits (207), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 79/301 (26%), Positives = 127/301 (42%), Gaps = 46/301 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +++IT LGQG+ VYEG + G + DE E RV +K
Sbjct 994 VAREKITMSRELGQGSFGMVYEGVAK---------GVVKDE----------PETRVAIKT 1034
Query 644 LD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
++ + + F AS+M + + H+ + GV +G +++ E + G L +LR
Sbjct 1035 VNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSL 1094
Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
R + P KM+ +A ++A ++YL VH ++ RN ++A
Sbjct 1095 RPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAE-------DF 1147
Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+ D G+ + + + + W++PE L G +T D W FG L EI
Sbjct 1148 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTYSDVWSFGVVLWEI 1205
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRD 865
E P Q S + F L +P +CP L L C Y P RPSF I+
Sbjct 1206 ATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISS 1265
Query 866 L 866
+
Sbjct 1266 I 1266
>sp|Q13308|PTK7_HUMAN Inactive tyrosine-protein kinase 7 OS=Homo
sapiens OX=9606 GN=PTK7 PE=1 SV=2
Length=1070
Score = 141 bits (355), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 101/353 (29%), Positives = 162/353 (46%), Gaps = 35/353 (10%)
Query 828 QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
+R + PE P++ +CL P Q +++ L T N S
Sbjct 733 KRLQKQPEGEEPEM-----ECLNGGPLQNGQPSAEIQEEVALTSLGSGPAAT-NKRHSTS 786
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE-MVAVKALKADCGPQHRSGWKQ 946
D F + L+ I LG+ FG+V L +G E +V VK+L++ Q + +++
Sbjct 787 DKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSK-DEQQQLDFRR 845
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIG 996
E+++ L H ++++ G C + + +V+EYV LG L+ +L +
Sbjct 846 ELEMFGKLNHANVVRLLGLCRE--AEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLS 903
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
Q + Q+ GM +L ++H+DLAARN L+ R VK+ GL+K V EYY
Sbjct 904 TKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDV-YNSEYYH 962
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
R+ P+ W +PE + E F SDVW+FGV ++E+ TH +
Sbjct 963 FRQ-AWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHG------------- 1008
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
GQ L +L RLP+P+ CP ++Y LM+ CW RP+F + L
Sbjct 1009 GQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 1061
Score = 77.0 bits (188), Expect = 8e-13, Method: Compositional matrix adjust.
Identities = 69/247 (28%), Positives = 108/247 (44%), Gaps = 25/247 (10%)
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
E V++K L L F + +++H ++ + G+C + MV EYV+ G L
Sbjct 824 ETLVLVKSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDL 883
Query 696 DVWLRRERGH------VPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILLARLGL 747
+LR + P++ K VA Q+A + +L N VH ++ RN L++
Sbjct 884 KQFLRISKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVS---- 939
Query 748 AEGTSPFIKLSDPGVGLGALSREE---RVERIP--WLAPECLPGGANSLSTAMDKWGFGA 802
+K+S G+ + E R +P W++PE + G ST D W FG
Sbjct 940 ---AQRQVKVSALGLSKDVYNSEYYHFRQAWVPLRWMSPEAILEG--DFSTKSDVWAFGV 994
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQR-QHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
+ E+ GE P ++ E Q + RLP+P CP +L L +C P RPSF
Sbjct 995 LMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSF 1054
Query 860 RTILRDL 866
I L
Sbjct 1055 SEIASAL 1061
>sp|P24062|IGF1R_RAT Insulin-like growth factor 1 receptor OS=Rattus
norvegicus OX=10116 GN=Igf1r PE=2 SV=2
Length=1370
Score = 141 bits (355), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 96/290 (33%), Positives = 148/290 (51%), Gaps = 37/290 (13%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGE-----MVAVKALKADCGPQHRSGWKQEIDILRTLY 955
R+LG+G FG V Y+ G + VA+K + + R + E +++
Sbjct 1004 RELGQGSFGMV----YEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFN 1059
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSI---------GLAQLLLFA 1004
H+++ G QG+ +L ++ME + G L+ YL R + L++++ A
Sbjct 1060 CHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSLRPEVENNLVLIPPSLSKMIQMA 1117
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+I +GMAYL+A ++HRDLAARN ++ D VKIGDFG+ + + E +YYR G P
Sbjct 1118 GEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYE-TDYYRKGGKGLLP 1176
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
V W +PE LK+ F SDVWSFGV L+E+ T + G++ Q VLR
Sbjct 1177 VRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQ---------GLSNEQ--VLR- 1224
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ G L +PD CP ++ LM+ CW+ RP+F +I +K E
Sbjct 1225 --FVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEME 1272
Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 80/298 (27%), Positives = 126/298 (42%), Gaps = 46/298 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +++IT LGQG+ VYEG + G + DE E RV +K
Sbjct 995 VAREKITMNRELGQGSFGMVYEGVAK---------GVVKDE----------PETRVAIKT 1035
Query 644 LD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
++ + + F AS+M + + H+ + GV +G +++ E + G L +LR
Sbjct 1036 VNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSL 1095
Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
R V P KM+ +A ++A ++YL VH ++ RN ++A
Sbjct 1096 RPEVENNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAE-------DF 1148
Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+ D G+ + + + + W++PE L G +T D W FG L EI
Sbjct 1149 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTHSDVWSFGVVLWEI 1206
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTIL 863
E P Q S + F L +P +CP L L C Y P RPSF I+
Sbjct 1207 ATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEII 1264
>sp|Q15375|EPHA7_HUMAN Ephrin type-A receptor 7 OS=Homo sapiens
OX=9606 GN=EPHA7 PE=1 SV=3
Length=998
Score = 140 bits (354), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 87/276 (32%), Positives = 143/276 (52%), Gaps = 21/276 (8%)
Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
+K R +G G FG+V S P VA+K LK + R + E I+
Sbjct 633 IKIERVIGAGEFGEVCSGRLKLPGKRDVA--VAIKTLKVGYTEKQRRDFLCEASIMGQFD 690
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAY 1013
H +++ +G K + +V+E++ G+L +L +H + QL+ + I GM Y
Sbjct 691 HPNVVHLEGVVTRG--KPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRY 748
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
L Y+HRDLAARN+L++++ + K+ DFGL++ + + E G PV W APE +
Sbjct 749 LADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAI 808
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF ASDVWS+G+ ++E++++ + P M+ + + +E G R
Sbjct 809 QYRKFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMSNQDVIKAIEEGYR 854
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
LP P CP ++ LM +CW+ E + RP FE ++ IL
Sbjct 855 LPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGIL 890
Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 82/294 (28%), Positives = 135/294 (46%), Gaps = 28/294 (10%)
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSH 667
RV G+G E G++ +PG+ +++ V +K L + + F AS+M Q H
Sbjct 637 RVIGAG--EFGEVCSGRLKLPGK---RDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDH 691
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
++ + GV RG ++V E++E+G LD +LR+ G + + + + +A+ + YL +
Sbjct 692 PNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLAD 751
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIP--WLA 780
VH ++ RNIL+ ++ K+SD G+ E V +IP W A
Sbjct 752 MGYVHRDLAARNILV-------NSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTA 804
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP 839
PE + ++A D W +G + E+ GE P S + + +RLP P CP
Sbjct 805 PEAIQ--YRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCP 862
Query 840 Q-LATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVLTV--NPDSPASD 888
L L C E +RP F I+ L ++ P++L L P SP D
Sbjct 863 AGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLD 916
>sp|P54759|EPHA7_RAT Ephrin type-A receptor 7 OS=Rattus norvegicus
OX=10116 GN=Epha7 PE=1 SV=1
Length=998
Score = 140 bits (354), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 87/276 (32%), Positives = 143/276 (52%), Gaps = 21/276 (8%)
Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
+K R +G G FG+V S P VA+K LK + R + E I+
Sbjct 633 IKIERVIGAGEFGEVCSGRLKLPGKRDVA--VAIKTLKVGYTEKQRRDFLCEASIMGQFD 690
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAY 1013
H +++ +G K + +V+E++ G+L +L +H + QL+ + I GM Y
Sbjct 691 HPNVVHLEGVVTRG--KPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRY 748
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
L Y+HRDLAARN+L++++ + K+ DFGL++ + + E G PV W APE +
Sbjct 749 LADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAI 808
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF ASDVWS+G+ ++E++++ + P M+ + + +E G R
Sbjct 809 QYRKFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMSNQDVIKAIEEGYR 854
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
LP P CP ++ LM +CW+ E + RP FE ++ IL
Sbjct 855 LPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGIL 890
Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 75/271 (28%), Positives = 126/271 (46%), Gaps = 24/271 (9%)
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSH 667
RV G+G E G++ +PG+ +++ V +K L + + F AS+M Q H
Sbjct 637 RVIGAG--EFGEVCSGRLKLPGK---RDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDH 691
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
++ + GV RG ++V E++E+G LD +LR+ G + + + + +A+ + YL +
Sbjct 692 PNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLAD 751
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIP--WLA 780
VH ++ RNIL+ ++ K+SD G+ E V +IP W A
Sbjct 752 MGYVHRDLAARNILV-------NSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTA 804
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP 839
PE + ++A D W +G + E+ GE P S + + +RLP P CP
Sbjct 805 PEAIQ--YRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCP 862
Query 840 Q-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
L L C E +RP F I+ L ++
Sbjct 863 AGLHQLMLDCWQKERAERPKFEQIVGILDKM 893
>sp|Q9VBW3|CAD96_DROME Tyrosine kinase receptor Cad96Ca OS=Drosophila
melanogaster OX=7227 GN=Cad96Ca PE=2 SV=2
Length=773
Score = 139 bits (351), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 99/296 (33%), Positives = 151/296 (51%), Gaps = 37/296 (13%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE---MVAVKALKADCGPQHRSGWKQEI 948
F + LK LGEG FG+V + + TN E VAVK LK R E+
Sbjct 465 FPRYRLKFFNILGEGAFGQV--WRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSEL 522
Query 949 DILRTLY-HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRH---SIGLAQ 999
+++++L H +++ GCC D+ +++EYV G L+ YL RH + G +
Sbjct 523 EVMKSLEPHINVVHLLGCCTDK--DPTFVILEYVNRGKLQTYLRSSRAERHYGNTHGKSN 580
Query 1000 LLL------FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+L F Q+ +GM YL ++ IHRDLAARN+L+ +D K+ DFG A+ V
Sbjct 581 VLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKI 640
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
Y R + +G P+ W A E L + F SD+WSFG+ ++E++T S+ P G
Sbjct 641 YER-KSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVT-LGSTPYP--------G 690
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
I+ V+R + G RL +P+ C E+Y++M CW + RP F +I +L
Sbjct 691 ISAAD--VMR---KVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQML 741
Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 57/223 (26%), Positives = 94/223 (42%), Gaps = 31/223 (14%)
Query 669 HLAFVH--GVCVRGPENIMVTEYVEHGPLDVWLRRER-----GHVPMAWKMVVA------ 715
H+ VH G C ++ EYV G L +LR R G+ ++ +
Sbjct 531 HINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRAERHYGNTHGKSNVLTSCDLTSF 590
Query 716 -QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE--ER 772
Q+A + YL ++ ++H ++ RNIL+ K++D G ++ + ER
Sbjct 591 MYQVAKGMDYLTSRGIIHRDLAARNILIT-------DDHTCKVADFGFARDVITSKIYER 643
Query 773 VER----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
I W+A E L N S D W FG + EI G P S ++ +
Sbjct 644 KSEGKLPIRWMATESLYD--NIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVR 701
Query 829 RQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+RL PE +L + C +++P +RP F I++ L +L
Sbjct 702 DGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKL 744
>sp|Q06805|TIE1_BOVIN Tyrosine-protein kinase receptor Tie-1 OS=Bos
taurus OX=9913 GN=TIE1 PE=2 SV=1
Length=1136
Score = 140 bits (354), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 98/281 (35%), Positives = 133/281 (47%), Gaps = 40/281 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961
+GEG+FG+V DG A+K LK + E+++L L +H +II
Sbjct 843 IGEGNFGQVIRAMIK--KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIIN 900
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-----------GLA------QLLLFA 1004
G CE++G L + +EY P G+L D+L + + G A QLL FA
Sbjct 901 LLGACENRG--YLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFA 958
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
GM YL + +IHRDLAARNVL+ + KI DFGL++ G E Y + G P
Sbjct 959 SDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSR----GEEVYVKKTMGRLP 1014
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
V W A E L + SDVWSFGV L+E+++ L G MT L
Sbjct 1015 VRWMAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCGMTCAEL 1060
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
E L + R+ +P C EVY LM+ CW RP F +
Sbjct 1061 YEKLPQAYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQI 1101
Score = 55.5 bits (132), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 72/332 (22%), Positives = 129/332 (39%), Gaps = 54/332 (16%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
+ L + R + P LN L + + +++ + GQ R + + L++ +
Sbjct 811 SGTLTLTRRPKPQPEPLNYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKML 870
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
+ + D RD EL V+ K+ HH ++ + G C
Sbjct 871 KEYASEND----HRDFAGELEVLCKL---GHH------------------PNIINLLGAC 905
Query 678 VRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLASAL 722
+ EY +G L +LR+ R + + A A+ +
Sbjct 906 ENRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGM 965
Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP--WL 779
YL K +H ++ RN+L+ G + K++D G+ G + ++ + R+P W+
Sbjct 966 QYLSEKQFIHRDLAARNVLV-------GENLASKIADFGLSRGEEVYVKKTMGRLPVRWM 1018
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838
A E L + +T D W FG L EI G P + +E + +R+ +P +C
Sbjct 1019 AIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQAYRMEQPRNC 1076
Query 839 -PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
++ L QC P +RP F I L R+
Sbjct 1077 DDEVYELMRQCWRDRPYERPPFAQIALQLGRM 1108
>sp|Q60751|IGF1R_MOUSE Insulin-like growth factor 1 receptor OS=Mus
musculus OX=10090 GN=Igf1r PE=1 SV=3
Length=1373
Score = 141 bits (355), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 95/291 (33%), Positives = 150/291 (52%), Gaps = 38/291 (13%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGE-----MVAVKALKADCGPQHRSGWKQEIDILRTLY 955
R+LG+G FG V Y+ G + VA+K + + R + E +++
Sbjct 1004 RELGQGSFGMV----YEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFN 1059
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSI-----GLAQLLLF 1003
H+++ G QG+ +L ++ME + G L+ YL ++++ L++++
Sbjct 1060 CHHVVRLLGVVS-QGQPTL-VIMELMTRGDLKSYLRSLRPEVEQNNLVLIPPSLSKMIQM 1117
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
A +I +GMAYL+A ++HRDLAARN ++ D VKIGDFG+ + + E +YYR G
Sbjct 1118 AGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYE-TDYYRKGGKGLL 1176
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
PV W +PE LK+ F SDVWSFGV L+E+ T + G++ Q VLR
Sbjct 1177 PVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQ---------GLSNEQ--VLR 1225
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ G L +PD CP ++ LM+ CW+ RP+F +I +K E
Sbjct 1226 ---FVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEME 1273
Score = 84.3 bits (207), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 80/299 (27%), Positives = 126/299 (42%), Gaps = 47/299 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +++IT LGQG+ VYEG + G + DE E RV +K
Sbjct 995 VAREKITMNRELGQGSFGMVYEGVAK---------GVVKDE----------PETRVAIKT 1035
Query 644 LD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
++ + + F AS+M + + H+ + GV +G +++ E + G L +LR
Sbjct 1036 VNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSL 1095
Query 703 RGHV---------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752
R V P KM+ +A ++A ++YL VH ++ RN ++A
Sbjct 1096 RPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAE-------D 1148
Query 753 PFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+K+ D G+ + + + + W++PE L G +T D W FG L E
Sbjct 1149 FTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTHSDVWSFGVVLWE 1206
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTIL 863
I E P Q S + F L +P +CP L L C Y P RPSF I+
Sbjct 1207 IATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEII 1265
>sp|Q8BKG3|PTK7_MOUSE Inactive tyrosine-protein kinase 7 OS=Mus
musculus OX=10090 GN=Ptk7 PE=1 SV=1
Length=1062
Score = 140 bits (354), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 91/301 (30%), Positives = 144/301 (48%), Gaps = 29/301 (10%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE-MVAVKALKADCGP 938
N A D F + L+ I LG+ FG+V L +G E +V VK+L++
Sbjct 771 TNKRHSAGDRMHFPRASLQPITTLGKSEFGEVFLAKAQGVEEGATETLVLVKSLQSR-DE 829
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------- 990
Q + +++E+++ L H ++++ G C + + +V+EYV LG L+ +L
Sbjct 830 QQQLDFRREVEMFGKLNHANVVRLLGLCRE--AEPHYMVLEYVDLGDLKQFLRISKNKDE 887
Query 991 --PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ Q + Q+ GM +L ++H+DLAARN L+ R VK+ GL+K V
Sbjct 888 KLKSQPLSTKQKVALCSQVALGMEHLSNNRFVHKDLAARNCLISAQRQVKVSALGLSKDV 947
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
EYY R+ P+ W +PE + E F SDVW+FGV ++E+ TH +
Sbjct 948 -YNSEYYHFRQ-AWVPLRWMSPEAVLEGDFSTKSDVWAFGVLMWEVFTHGEMPHG----- 1000
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
GQ L +L RLP+P+ CP ++Y LM+ CW RP+F +
Sbjct 1001 --------GQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWAPNPKDRPSFSEIAST 1052
Query 1169 L 1169
L
Sbjct 1053 L 1053
Score = 77.0 bits (188), Expect = 9e-13, Method: Compositional matrix adjust.
Identities = 69/247 (28%), Positives = 108/247 (44%), Gaps = 25/247 (10%)
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
E V++K L L F + +++H ++ + G+C + MV EYV+ G L
Sbjct 816 ETLVLVKSLQSRDEQQQLDFRREVEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDL 875
Query 696 DVWLRRERGH------VPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILLARLGL 747
+LR + P++ K VA Q+A + +L N VH ++ RN L++
Sbjct 876 KQFLRISKNKDEKLKSQPLSTKQKVALCSQVALGMEHLSNNRFVHKDLAARNCLIS---- 931
Query 748 AEGTSPFIKLSDPGVGLGALSREE---RVERIP--WLAPECLPGGANSLSTAMDKWGFGA 802
+K+S G+ + E R +P W++PE + G ST D W FG
Sbjct 932 ---AQRQVKVSALGLSKDVYNSEYYHFRQAWVPLRWMSPEAVLEG--DFSTKSDVWAFGV 986
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQR-QHRLPEPS-CP-QLATLTSQCLTYEPTQRPSF 859
+ E+ GE P ++ E Q + RLP+P CP +L L +C P RPSF
Sbjct 987 LMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWAPNPKDRPSF 1046
Query 860 RTILRDL 866
I L
Sbjct 1047 SEIASTL 1053
>sp|P14617|INSRR_CAVPO Insulin receptor-related protein OS=Cavia
porcellus OX=10141 GN=INSRR PE=3 SV=1
Length=1300
Score = 140 bits (354), Expect = 2e-32, Method: Compositional matrix adjust.
Identities = 95/291 (33%), Positives = 148/291 (51%), Gaps = 41/291 (14%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDG--TGEM---VAVKALKADCGPQHRSGWKQEI 948
+ + IR+LG+G FG V Y+ G GE VA+K + P+ R + +E
Sbjct 976 REQISIIRELGQGSFGMV----YEGVAKGLEAGEESTPVALKTVNELASPRERIEFLKEA 1031
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------------PRHSI 995
+++ H+++ G QG+ +L ++ME + G L+ +L PR ++
Sbjct 1032 SVMKAFQCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSHLRSLRPEAENNPGIPRPAL 1089
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
G ++ A +I +GMAYL A ++HRDLAARN ++ D VKIGDFG+ + V E +YY
Sbjct 1090 G--DMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYE-TDYY 1146
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
R G PV W APE LK+ F SDVWSFGV L+E++T + G++
Sbjct 1147 RKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQ---------GLS 1197
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
Q+ + + G L + CP ++ LM +CW+ RPTF ++
Sbjct 1198 NEQV-----LKFVMDGGVLEELEDCPHQLQELMSSCWQQNPRLRPTFTQIL 1243
Score = 75.1 bits (183), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 76/302 (25%), Positives = 125/302 (41%), Gaps = 44/302 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +++I+ + LGQG+ VYEG + +G+ + P+ L+ V ++
Sbjct 974 VPREQISIIRELGQGSFGMVYEGVAKGLEAGE-------ESTPVA--------LKTVNEL 1018
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
P + F + AS+M H+ + GV +G +++ E + G L LR R
Sbjct 1019 ASPRER---IEFLKEASVMKAFQCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLR 1075
Query 704 GHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
P M+ +A ++A ++YL VH ++ RN ++++
Sbjct 1076 PEAENNPGIPRPALGDMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQ-------DFT 1128
Query 755 IKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+K+ D G+ + + + + W+APE L G +T D W FG L EI
Sbjct 1129 VKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGI--FTTHSDVWSFGVVLWEIV 1186
Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSFRTILRDL 866
E P Q S + F L E CP QL L S C P RP+F IL +
Sbjct 1187 TLAEQPYQGLSNEQVLKFVMDGGVLEELEDCPHQLQELMSSCWQQNPRLRPTFTQILNSI 1246
Query 867 TR 868
+
Sbjct 1247 QK 1248
>sp|Q64434|PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus musculus
OX=10090 GN=Ptk6 PE=1 SV=1
Length=451
Score = 134 bits (338), Expect = 4e-32, Method: Compositional matrix adjust.
Identities = 93/275 (34%), Positives = 144/275 (52%), Gaps = 28/275 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+ LG G+FG+V ++ G VAVK + D H+ ++ EI ++ L H+HI+
Sbjct 195 KKLGAGYFGEV----FEALWKGQVH-VAVKVISRD-NLLHQHTFQAEIQAMKKLRHKHIL 248
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ ++ E +P G+L L ++ + +L+ FA Q+ EGM YL +Q
Sbjct 249 SLYAVA--TAGDPVYIITELMPKGNLLQLLRDSDEKALPILELVDFASQVAEGMCYLESQ 306
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+YIHRDLAARNVL+ + L K+GDFGLA+ V E + + + P W APE L
Sbjct 307 NYIHRDLAARNVLVTENNLCKVGDFGLARLVKED---IYLSHEHNVPYKWTAPEALSRGH 363
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ SDVWSFGV L+E+ + Q P G++ + T LR ++ G R+P P
Sbjct 364 YSIKSDVWSFGVLLHEIFS---RGQMPYP------GMSNHE-TFLR----VDAGYRMPCP 409
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+CP ++ LM +CW + RP F++L L +
Sbjct 410 LECPPNIHKLMLSCWSRDPKQRPCFKDLCEKLTGI 444
Score = 79.7 bits (195), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 68/239 (28%), Positives = 107/239 (45%), Gaps = 11/239 (5%)
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
+GQ + V +KV+ + F M ++ H H+ ++ V G ++TE +
Sbjct 211 KGQ-VHVAVKVISRDNLLHQHTFQAEIQAMKKLRHKHILSLYAVATAGDPVYIITELMPK 269
Query 693 GPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE-G 750
G L LR + +P+ + A Q+A + YLE++N +H ++ RN+L+ L + G
Sbjct 270 GNLLQLLRDSDEKALPILELVDFASQVAEGMCYLESQNYIHRDLAARNVLVTENNLCKVG 329
Query 751 TSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+L + LS E V W APE L G S+ + D W FG L EI
Sbjct 330 DFGLARLVKEDI---YLSHEHNVP-YKWTAPEALSRGHYSIKS--DVWSFGVLLHEIFSR 383
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEPTQRPSFRTILRDLT 867
G+ P S E +R+P P C P + L C + +P QRP F+ + LT
Sbjct 384 GQMPYPGMSNHETFLRVDAGYRMPCPLECPPNIHKLMLSCWSRDPKQRPCFKDLCEKLT 442
>sp|P18106|FER_DROME Tyrosine-protein kinase Fer OS=Drosophila
melanogaster OX=7227 GN=FER PE=1 SV=3
Length=1325
Score = 140 bits (352), Expect = 4e-32, Method: Compositional matrix adjust.
Identities = 94/271 (35%), Positives = 137/271 (51%), Gaps = 29/271 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G+FG V Y T VAVK + + + + QE IL+ H +I+K
Sbjct 1069 IGRGNFGDV----YKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKL 1124
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHYI 1020
G C + + + +VME V GSL YL ++S GL Q + + GM YL +++ I
Sbjct 1125 IGICVQK--QPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCI 1182
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVFWYAPECLKEYKF 1078
HRDLAARN L+D + VKI DFG+++ E EY + DG PV W APE L K+
Sbjct 1183 HRDLAARNCLVDLEHSVKISDFGMSR---EEEEY--IVSDGMKQIPVKWTAPEALNFGKY 1237
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
DVWS+G+ ++E+ + D+ S MT R E ++ G R+P P
Sbjct 1238 TSLCDVWSYGILMWEIFSKGDTPYSG--------------MTNSRARERIDTGYRMPTPK 1283
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P E+Y LM CW +A RP F+ + ++
Sbjct 1284 STPEEMYRLMLQCWAADAESRPHFDEIYNVV 1314
Score = 80.1 bits (196), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 64/241 (27%), Positives = 108/241 (45%), Gaps = 34/241 (14%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F + ++ Q H ++ + G+CV+ ++V E V G L +LR+ + +M +
Sbjct 1106 FLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGM 1165
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-- 772
+ A+ + YLE+KN +H ++ RN L+ +K+SD G +SREE
Sbjct 1166 CRDAAAGMRYLESKNCIHRDLAARNCLV-------DLEHSVKISDFG-----MSREEEEY 1213
Query 773 -----VERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
+++IP W APE L G ++ D W +G + EI G+ P + S
Sbjct 1214 IVSDGMKQIPVKWTAPEALNFG--KYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARE 1271
Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
+R+P P S P ++ L QC + RP F I +N+ D L + D
Sbjct 1272 RIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEI---------YNVVDALILRLD 1322
Query 884 S 884
+
Sbjct 1323 N 1323
>sp|Q61772|EPHA7_MOUSE Ephrin type-A receptor 7 OS=Mus musculus
OX=10090 GN=Epha7 PE=1 SV=2
Length=998
Score = 139 bits (351), Expect = 4e-32, Method: Compositional matrix adjust.
Identities = 86/276 (31%), Positives = 143/276 (52%), Gaps = 21/276 (8%)
Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
+K R +G G FG+V S P VA+K LK + R + E I+
Sbjct 633 IKIERVIGAGEFGEVCSGRLKLPGKRDVA--VAIKTLKVGYTEKQRRDFLCEASIMGQFD 690
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAY 1013
H +++ +G K + +V+E++ G+L +L +H + QL+ + I GM Y
Sbjct 691 HPNVVHLEGVVTRG--KPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRY 748
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
L Y+HRDLAARN+L++++ + K+ DFGL++ + + E G PV W APE +
Sbjct 749 LADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAI 808
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF ASDVWS+G+ ++E++++ + P M+ + + +E G R
Sbjct 809 QYRKFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMSNQDVIKAIEEGYR 854
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
LP P CP ++ LM +CW+ + + RP FE ++ IL
Sbjct 855 LPAPMDCPAGLHQLMLDCWQKDRAERPKFEQIVGIL 890
Score = 87.4 bits (215), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 74/271 (27%), Positives = 126/271 (46%), Gaps = 24/271 (9%)
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSH 667
RV G+G E G++ +PG+ +++ V +K L + + F AS+M Q H
Sbjct 637 RVIGAG--EFGEVCSGRLKLPGK---RDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDH 691
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
++ + GV RG ++V E++E+G LD +LR+ G + + + + +A+ + YL +
Sbjct 692 PNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLAD 751
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIP--WLA 780
VH ++ RNIL+ ++ K+SD G+ E V +IP W A
Sbjct 752 MGYVHRDLAARNILV-------NSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTA 804
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP 839
PE + ++A D W +G + E+ GE P S + + +RLP P CP
Sbjct 805 PEAIQ--YRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCP 862
Query 840 Q-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
L L C + +RP F I+ L ++
Sbjct 863 AGLHQLMLDCWQKDRAERPKFEQIVGILDKM 893
>sp|P00541|FPS_AVISP Tyrosine-protein kinase transforming protein
Fps OS=Avian sarcoma virus (strain PRCII) OX=11880 GN=V-FPS
PE=3 SV=1
Length=533
Score = 135 bits (341), Expect = 5e-32, Method: Compositional matrix adjust.
Identities = 88/274 (32%), Positives = 139/274 (51%), Gaps = 27/274 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G+FG+V + D T VAVK+ + P+ ++ + QE IL+ H +I++
Sbjct 278 IGRGNFGEV--FSGRLRADNTP--VAVKSCRETLPPELKAKFLQEARILKQYNHPNIVRL 333
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C + + + +VME V G +L + + +L+ + GM YL ++H I
Sbjct 334 IGVCTQK--QPIYIVMELVQGGDFLSFLRSKGPHLKMKELIKMMENAAAGMEYLESKHCI 391
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARN L+ +KI DFG+++ +G Y PV W APE L ++
Sbjct 392 HRDLAARNCLVTEKNTLKISDFGMSRQEEDG-VYASTGGMKQIPVKWTAPEALNYGRYSS 450
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWSFG+ L+E + L + ++ + E +E+G RL P++C
Sbjct 451 ESDVWSFGILLWEAFS--------------LGAVPYANLSNQQTREAIEQGVRLEPPEQC 496
Query 1141 PCEVYHLMKNCWETEASFRPTF----ENLIPILK 1170
P +VY LM+ CWE + RP+F ++LI I K
Sbjct 497 PEDVYRLMQRCWEYDPRRRPSFGAVHQDLIAIRK 530
Score = 86.3 bits (212), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 73/284 (26%), Positives = 127/284 (45%), Gaps = 40/284 (14%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
+G+G V+ GRLR D P+ ++ + L P ++
Sbjct 278 IGRGNFGEVFSGRLRA------------DNTPVA--------VKSCRETLPP---ELKAK 314
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F + A ++ Q +H ++ + GVC + +V E V+ G +LR + H+ M + +
Sbjct 315 FLQEARILKQYNHPNIVRLIGVCTQKQPIYIVMELVQGGDFLSFLRSKGPHLKMKELIKM 374
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSRE 770
+ A+ + YLE+K+ +H ++ RN L+ +K+SD G+ G +
Sbjct 375 MENAAAGMEYLESKHCIHRDLAARNCLVTEKNT-------LKISDFGMSRQEEDGVYAST 427
Query 771 ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
+++IP W APE L G S+ D W FG L E G P + S + +
Sbjct 428 GGMKQIPVKWTAPEALNYG--RYSSESDVWSFGILLWEAFSLGAVPYANLSNQQTREAIE 485
Query 829 RQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ RL P CP+ + L +C Y+P +RPSF + +DL ++
Sbjct 486 QGVRLEPPEQCPEDVYRLMQRCWEYDPRRRPSFGAVHQDLIAIR 529
>sp|Q9TTY2|FER_CANLF Tyrosine-protein kinase Fer OS=Canis lupus
familiaris OX=9615 GN=FER PE=2 SV=1
Length=823
Score = 138 bits (348), Expect = 5e-32, Method: Compositional matrix adjust.
Identities = 91/276 (33%), Positives = 139/276 (50%), Gaps = 27/276 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G+FG+V D T VAVK K D + + + QE IL+ H +I+K
Sbjct 569 LGKGNFGEV---YKGILKDKTA--VAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKL 623
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C + + + ++ME VP G +L + I L QL+ F+ GM+YL +++ I
Sbjct 624 IGVCTQR--QPIYIIMELVPGGDFLSFLRKKKDEIKLKQLVKFSLDAASGMSYLESKNCI 681
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARN L+ + ++KI DFG+++ G Y P+ W APE L ++
Sbjct 682 HRDLAARNCLVGENNVLKISDFGMSRQEDGG--VYSSSGLKQIPIKWTAPEALNYGRYSS 739
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA-QGQMTVLRLTELLERGERLPRPDK 1139
SDVWSFG+ L+E + +G+ MT + TE +ERG R+ P
Sbjct 740 ESDVWSFGILLWETFS---------------LGVCPYPGMTNQQATEQVERGYRISAPQH 784
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
CP +++ +M CW+ + RP F L L + +K
Sbjct 785 CPEDIFKIMMKCWDYKPENRPKFSELQKELTVIKKK 820
Score = 89.7 bits (221), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 60/229 (26%), Positives = 110/229 (48%), Gaps = 16/229 (7%)
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
++ + F + A ++ Q H ++ + GVC + ++ E V G +LR+++ + +
Sbjct 599 QELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPIYIIMELVPGGDFLSFLRKKKDEIKL 658
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---G 765
+ + AS +SYLE+KN +H ++ RN L+ G + +K+SD G+ G
Sbjct 659 KQLVKFSLDAASGMSYLESKNCIHRDLAARNCLV-------GENNVLKISDFGMSRQEDG 711
Query 766 ALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ +++IP W APE L G S+ D W FG L E G P + +
Sbjct 712 GVYSSSGLKQIPIKWTAPEALNYG--RYSSESDVWSFGILLWETFSLGVCPYPGMTNQQA 769
Query 824 EHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+R +R+ P CP+ + + +C Y+P RP F + ++LT ++
Sbjct 770 TEQVERGYRISAPQHCPEDIFKIMMKCWDYKPENRPKFSELQKELTVIK 818
>sp|Q60805|MERTK_MOUSE Tyrosine-protein kinase Mer OS=Mus musculus
OX=10090 GN=Mertk PE=1 SV=1
Length=994
Score = 139 bits (349), Expect = 6e-32, Method: Compositional matrix adjust.
Identities = 94/288 (33%), Positives = 139/288 (48%), Gaps = 29/288 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEI 948
V + L + LGEG FG V + DGT + VAVK +K D Q + E
Sbjct 575 VVIDRNLLVLGKVLGEGEFGSV-MEGNLKQEDGTSQKVAVKTMKLDNFSQREIEEFLSEA 633
Query 949 DILRTLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGSLRDYL--------PRHSIGL 997
++ H ++I+ G C QG +++ ++ G L +L P++ I L
Sbjct 634 ACMKDFNHPNVIRLLGVCIELSSQGIPKPMVILPFMKYGDLHTFLLYSRLNTGPKY-IHL 692
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
LL F I +GM YL ++++HRDLAARN +L +D V + DFGL+K + G +YYR
Sbjct 693 QTLLKFMMDIAQGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQ 751
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
PV W A E L + + SDVW+FGVT++E+ T G+
Sbjct 752 GRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEITTR---------GMTPYPGVQNH 802
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+M + L G RL +P+ C E+Y +M +CW + RPTF L
Sbjct 803 EM-----YDYLLHGHRLKQPEDCLDELYDIMYSCWSADPLDRPTFSVL 845
Score = 71.6 bits (174), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 75/317 (24%), Positives = 134/317 (42%), Gaps = 35/317 (11%)
Query 606 GRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664
G++ EG G EG + ED Q++ V LD F A+ M
Sbjct 585 GKVLGEGEFGSVMEGNLKQED------GTSQKVAVKTMKLDNFSQREIEEFLSEAACMKD 638
Query 665 VSHTHLAFVHGVCVR-----GPENIMVTEYVEHGPLDVWLRRER-----GHVPMAWKMVV 714
+H ++ + GVC+ P+ +++ ++++G L +L R ++ + +
Sbjct 639 FNHPNVIRLLGVCIELSSQGIPKPMVILPFMKYGDLHTFLLYSRLNTGPKYIHLQTLLKF 698
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+A + YL N+N +H ++ RN +L R + + F LS + G R+ R+
Sbjct 699 MMDIAQGMEYLSNRNFLHRDLAARNCML-RDDMTVCVADF-GLSK-KIYSGDYYRQGRIA 755
Query 775 RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832
++P W+A E L ++ D W FG T+ EI G P E + HR
Sbjct 756 KMPVKWIAIESL--ADRVYTSKSDVWAFGVTMWEITTRGMTPYPGVQNHEMYDYLLHGHR 813
Query 833 L--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
L PE +L + C + +P RP+F + RLQ L++ L PD+ +
Sbjct 814 LKQPEDCLDELYDIMYSCWSADPLDRPTFSVL-----RLQLEKLSESL---PDAQDKESI 865
Query 891 VF-HKRYLKKIRDLGEG 906
++ + + L+ + G
Sbjct 866 IYINTQLLESCEGIANG 882
>sp|Q91845|EPA4A_XENLA Ephrin type-A receptor 4-A OS=Xenopus laevis
OX=8355 GN=epha4-a PE=2 SV=1
Length=986
Score = 139 bits (349), Expect = 6e-32, Method: Compositional matrix adjust.
Identities = 87/277 (31%), Positives = 143/277 (52%), Gaps = 23/277 (8%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTL 954
+K + +G G FG+V C G E+ VA+K LKA + R + E I+
Sbjct 620 IKIEKVIGVGEFGEV---CSGRLKVPGKREIYVAIKTLKAGYTDKQRRDFLSEASIMGQF 676
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMA 1012
H +II +G K + ++ EY+ GSL +L ++ + QL+ + I GM
Sbjct 677 DHPNIIHLEGVVTKC--KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGILRGIGSGMK 734
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
YL Y+HRDLAARN+L++++ + K+ DFG+++ + + E G P+ W APE
Sbjct 735 YLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEA 794
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ KF ASDVWS+G+ ++E++++ + P M+ + + +E G
Sbjct 795 IAYRKFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMSNQDVIKAIEEGY 840
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
RLP P CP ++ LM +CW+ E S RP F ++ +L
Sbjct 841 RLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVSML 877
Score = 94.0 bits (232), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 74/259 (29%), Positives = 121/259 (47%), Gaps = 24/259 (9%)
Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
VPG+ +E+ V +K L + D F AS+M Q H ++ + GV + +++
Sbjct 641 VPGK---REIYVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMII 697
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TEY+E+G LD +LR+ G + + + + + S + YL + + VH ++ RNIL+
Sbjct 698 TEYMENGSLDAFLRKNDGRFTVIQLVGILRGIGSGMKYLSDMSYVHRDLAARNILV---- 753
Query 747 LAEGTSPFIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWG 799
++ K+SD G+ E R +IP W APE + ++A D W
Sbjct 754 ---NSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAI--AYRKFTSASDVWS 808
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRP 857
+G + E+ GE P S + + +RLP P CP L L C E + RP
Sbjct 809 YGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRP 868
Query 858 SFRTILRDLTRL--QPHNL 874
F I+ L +L P++L
Sbjct 869 KFGQIVSMLDKLIRNPNSL 887
>sp|O73791|TIE2_DANRE Angiopoietin-1 receptor OS=Danio rerio OX=7955
GN=tek PE=1 SV=1
Length=1116
Score = 139 bits (349), Expect = 6e-32, Method: Compositional matrix adjust.
Identities = 99/291 (34%), Positives = 141/291 (48%), Gaps = 40/291 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL-RTLYHEHIIK 961
LGEG+FG+V DG AVK +K + E+++L R H++II
Sbjct 822 LGEGNFGQV--LKARIRKDGLRMDAAVKRMKDYASQDDHRDFAGELEVLCRLGPHKNIIH 879
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFA 1004
G CE +G L L +E+ P G+L D+L + ++ QLL F+
Sbjct 880 LLGACEHRGY--LYLAIEFAPHGNLLDFLRKSRVLETDPAFAIAHRTASTLSSQQLLAFS 937
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+ GM+YL + +IHRDLAARNVL+ + + KI DFGL++ G E Y + G P
Sbjct 938 ADVARGMSYLSQKQFIHRDLAARNVLVGENFVAKIADFGLSR----GQEVYVKKTMGRLP 993
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
V W A E L + SDVWS+GV L+E+++ L G MT L
Sbjct 994 VRWMAIESLNYSVYTTNSDVWSYGVLLWEVVS--------------LGGTPYCGMTCAEL 1039
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
E L G RL +P C EVY LM+ CW + RP+F ++ L + E+
Sbjct 1040 YEKLPLGFRLEKPLNCDDEVYELMQQCWREKPFERPSFSQILLSLGRMLEE 1090
Score = 62.4 bits (150), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 78/312 (25%), Positives = 125/312 (40%), Gaps = 51/312 (16%)
Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG-SGDPEEGKMDDEDPLVPGRDRGQEL 637
L F + +I LG+G V + R+R +G D +M D RD EL
Sbjct 806 LVFPALQWSDIQFQDVLGEGNFGQVLKARIRKDGLRMDAAVKRMKDYASQDDHRDFAGEL 865
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V+ + L P H ++ + G C + E+ HG L
Sbjct 866 EVLCR-LGP--------------------HKNIIHLLGACEHRGYLYLAIEFAPHGNLLD 904
Query 698 WLRRER--------GHVPMAWKMVVAQQL-------ASALSYLENKNLVHGNVCGRNILL 742
+LR+ R + +QQL A +SYL K +H ++ RN+L+
Sbjct 905 FLRKSRVLETDPAFAIAHRTASTLSSQQLLAFSADVARGMSYLSQKQFIHRDLAARNVLV 964
Query 743 ARLGLAEGTSPFIKLSDPGVGLGA-LSREERVERIP--WLAPECLPGGANSLSTAMDKWG 799
G + K++D G+ G + ++ + R+P W+A E L + +T D W
Sbjct 965 -------GENFVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESL--NYSVYTTNSDVWS 1015
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEPTQRP 857
+G L E+ G P + +E RL +P +C ++ L QC +P +RP
Sbjct 1016 YGVLLWEVVSLGGTPYCGMTCAELYEKLPLGFRLEKPLNCDDEVYELMQQCWREKPFERP 1075
Query 858 SFRTILRDLTRL 869
SF IL L R+
Sbjct 1076 SFSQILLSLGRM 1087
>sp|Q07496|EPHA4_CHICK Ephrin type-A receptor 4 OS=Gallus gallus
OX=9031 GN=EPHA4 PE=1 SV=2
Length=986
Score = 139 bits (349), Expect = 7e-32, Method: Compositional matrix adjust.
Identities = 90/294 (31%), Positives = 148/294 (50%), Gaps = 31/294 (11%)
Query 888 DPTVFHKRYLKKI--------RDLGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCG 937
DP + + K+I + +G G FG+V C G E+ VA+K LKA
Sbjct 604 DPNQAVREFAKEIDASCIKIEKVIGVGEFGEV---CSGRLKVPGKREICVAIKTLKAGYT 660
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995
+ R + E I+ H +II +G K + ++ EY+ GSL +L ++
Sbjct 661 DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKC--KPVMIITEYMENGSLDAFLRKNDGRF 718
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFG+++ + + E
Sbjct 719 TVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAA 778
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
G P+ W APE + KF ASDVWS+G+ ++E++++ + P
Sbjct 779 YTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY---GERP----------- 824
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
M+ + + +E G RLP P CP ++ LM +CW+ E S RP F ++ +L
Sbjct 825 YWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNML 878
Score = 94.0 bits (232), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 94/357 (26%), Positives = 154/357 (43%), Gaps = 53/357 (15%)
Query 586 QKEITQLSHLGQGTRTNV----YE---------------GRLRVEGS-GDPEEGKMDDED 625
++E + HL QG RT V YE +++E G E G++
Sbjct 580 KQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGR 639
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
VPG+ +E+ V +K L + D F AS+M Q H ++ + GV + +
Sbjct 640 LKVPGK---REICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVM 696
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
++TEY+E+G LD +LR+ G + + + + + S + YL + + VH ++ RNIL+
Sbjct 697 IITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILV-- 754
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDK 797
++ K+SD G+ E R +IP W APE + ++A D
Sbjct 755 -----NSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAI--AYRKFTSASDV 807
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQ 855
W +G + E+ GE P S + + +RLP P CP L L C E +
Sbjct 808 WSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSD 867
Query 856 RPSFRTILRDLTRL--QPHNLA---------DVLTVNPDSPASDPTVFHKRYLKKIR 901
RP F I+ L +L P++L ++P SP V +L+ I+
Sbjct 868 RPKFGQIVNMLDKLIRNPNSLKRTGSESSRPSTALLDPSSPEFSAVVSVSDWLQAIK 924
>sp|Q60750|EPHA1_MOUSE Ephrin type-A receptor 1 OS=Mus musculus
OX=10090 GN=Epha1 PE=1 SV=2
Length=977
Score = 138 bits (348), Expect = 7e-32, Method: Compositional matrix adjust.
Identities = 87/266 (33%), Positives = 134/266 (50%), Gaps = 22/266 (8%)
Query 903 LGEGHFGKVSLYCYD-PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG FG+V P+ D + VA+K LK + + +E I+ H HI++
Sbjct 631 IGEGEFGEVYRGALRLPSQDC--KTVAIKTLKDTSPDGYWWNFLREATIMGQFNHPHILR 688
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019
+G + K + ++ E++ G+L +L LA QL+ I GM L +Y
Sbjct 689 LEGVITKR--KPIMIITEFMENGALDAFLKEREDQLAPGQLVAMLLGIASGMNCLSGHNY 746
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDLAARN+L++ + K+ DFGL + + + Y + G P+ W APE + F
Sbjct 747 VHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYET-QGGKIPIRWTAPEAIAHRIFT 805
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
ASDVWSFG+ ++E+L+ D G+M+ + + +E G RLP P
Sbjct 806 TASDVWSFGIVMWEVLSFGDK--------------PYGEMSNQEVMKSIEDGYRLPPPVD 851
Query 1140 CPCEVYHLMKNCWETEASFRPTFENL 1165
CP +Y LMKNCW + + RP F L
Sbjct 852 CPAPLYELMKNCWAYDRARRPHFLQL 877
Score = 90.1 bits (222), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 73/253 (29%), Positives = 116/253 (46%), Gaps = 16/253 (6%)
Query 639 VVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V +K L D S F A++M Q +H H+ + GV + +++TE++E+G LD
Sbjct 654 VAIKTLKDTSPDGYWWNFLREATIMGQFNHPHILRLEGVITKRKPIMIITEFMENGALDA 713
Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF--I 755
+L+ + + + +AS ++ L N VH ++ RNIL+ + L S F
Sbjct 714 FLKEREDQLAPGQLVAMLLGIASGMNCLSGHNYVHRDLAARNILVNQ-NLCCKVSDFGLT 772
Query 756 KLSDPGVGLGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
+L D G + E + +IP W APE + +TA D W FG + E+ G+
Sbjct 773 RLLDDFDG----TYETQGGKIPIRWTAPEAI--AHRIFTTASDVWSFGIVMWEVLSFGDK 826
Query 814 PLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL-- 869
P S E + +RLP P CP L L C Y+ +RP F + L +L
Sbjct 827 PYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFLQLQAHLEQLLT 886
Query 870 QPHNLADVLTVNP 882
PH+L + +P
Sbjct 887 DPHSLRTIANFDP 899
>sp|Q62838|MUSK_RAT Muscle, skeletal receptor tyrosine protein
kinase OS=Rattus norvegicus OX=10116 GN=Musk PE=1 SV=1
Length=868
Score = 138 bits (347), Expect = 8e-32, Method: Compositional matrix adjust.
Identities = 89/318 (28%), Positives = 155/318 (49%), Gaps = 53/318 (17%)
Query 892 FHKRYLKKIRDLGEGHFGKV------SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
+ + ++ +RD+GEG FG+V L Y+P MVAVK LK + ++ ++
Sbjct 569 YPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFT-----MVAVKMLKEEASADMQADFQ 623
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------- 994
+E ++ + +I+K G C K + L+ EY+ G L ++L S
Sbjct 624 REAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSD 681
Query 995 --------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040
+ A+ L A+Q+ GMAYL + ++HRDLA RN L+ + +VKI
Sbjct 682 LSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIA 741
Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100
DFGL++ + +YY+ + P+ W PE + ++ SDVW++GV L+E+ ++
Sbjct 742 DFGLSRNIYSA-DYYKADGNDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSY--- 797
Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
G+A ++ + G L P+ CP E+Y+LM+ CW + RP
Sbjct 798 ------GLQPYYGMAHEEVIY-----YVRDGNILACPENCPLELYNLMRLCWSKLPADRP 846
Query 1161 TFENLIPILKTVHEKYQG 1178
+F ++ IL+ + E+ +G
Sbjct 847 SFCSIHRILQRMCERAEG 864
Score = 77.0 bits (188), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 67/263 (25%), Positives = 120/263 (46%), Gaps = 41/263 (16%)
Query 639 VVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V +K+L + + D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+
Sbjct 605 VAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNE 664
Query 698 WLRRERGH-----------------------VPMAWKMVVAQQLASALSYLENKNLVHGN 734
+LR H + A ++ +A+Q+A+ ++YL + VH +
Sbjct 665 FLRSMSPHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRD 724
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGA 788
+ RN L+ G + +K++D G+ S + + + IP W+ PE +
Sbjct 725 LATRNCLV-------GENMVVKIADFGLSRNIYSADYYKADGNDAIPIRWMPPESI--FY 775
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTS 846
N +T D W +G L EI G P + E ++ + + L P +CP +L L
Sbjct 776 NRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILACPENCPLELYNLMR 835
Query 847 QCLTYEPTQRPSFRTILRDLTRL 869
C + P RPSF +I R L R+
Sbjct 836 LCWSKLPADRPSFCSIHRILQRM 858
>sp|Q03137|EPHA4_MOUSE Ephrin type-A receptor 4 OS=Mus musculus
OX=10090 GN=Epha4 PE=1 SV=2
Length=986
Score = 138 bits (347), Expect = 1e-31, Method: Compositional matrix adjust.
Identities = 78/245 (32%), Positives = 129/245 (53%), Gaps = 18/245 (7%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VA+K LKA + R + E I+ H +II +G K + ++ EY+ GSL
Sbjct 650 VAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKC--KPVMIITEYMENGSL 707
Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L ++ + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFG+
Sbjct 708 DAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGM 767
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
++ + + E G P+ W APE + KF ASDVWS+G+ ++E++++ + P
Sbjct 768 SRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY---GERP 824
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
M+ + + +E G RLP P CP ++ LM +CW+ E S RP F
Sbjct 825 -----------YWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQ 873
Query 1165 LIPIL 1169
++ +L
Sbjct 874 IVNML 878
Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 80/295 (27%), Positives = 133/295 (45%), Gaps = 33/295 (11%)
Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
VPG+ +E+ V +K L + D F AS+M Q H ++ + GV + +++
Sbjct 642 VPGK---REICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMII 698
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TEY+E+G LD +LR+ G + + + + + S + YL + + VH ++ RNIL+
Sbjct 699 TEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILV---- 754
Query 747 LAEGTSPFIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWG 799
++ K+SD G+ E R +IP W APE + ++A D W
Sbjct 755 ---NSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAI--AYRKFTSASDVWS 809
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRP 857
+G + E+ GE P S + + +RLP P CP L L C E + RP
Sbjct 810 YGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRP 869
Query 858 SFRTILRDLTRL--QPHNLA---------DVLTVNPDSPASDPTVFHKRYLKKIR 901
F I+ L +L P++L + ++P SP V +L+ I+
Sbjct 870 KFGQIVNMLDKLIRNPNSLKRTGSESSRPNTALLDPSSPEFSAVVSVGDWLQAIK 924
>sp|Q03146|DDR1_MOUSE Epithelial discoidin domain-containing receptor
1 OS=Mus musculus OX=10090 GN=Ddr1 PE=2 SV=2
Length=911
Score = 137 bits (346), Expect = 1e-31, Method: Compositional matrix adjust.
Identities = 98/309 (32%), Positives = 139/309 (45%), Gaps = 47/309 (15%)
Query 892 FHKRYLKKIRDLGEGHFGKVSL-YCYDPTN-----------DGTGEMVAVKALKADCGPQ 939
F + L+ LGEG FG+V L DP + G +VAVK L+ D
Sbjct 603 FPRSRLRFKEKLGEGQFGEVHLCEVEDPQDLVSSDFPISVHKGHPLLVAVKILRPDATKN 662
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------ 993
R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L
Sbjct 663 ARNDFLKEVKIMSRLKDPNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSARQLENKA 720
Query 994 --------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
+I LL QI GM YL +++HRDLA RN L+ + +KI
Sbjct 721 TQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKI 780
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+L C
Sbjct 781 ADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCR 839
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER---LPRPDKCPCEVYHLMKNCWETEA 1156
S + G + + E R L RP CP +Y LM CW E
Sbjct 840 S---------QPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQTLYELMLRCWSREP 890
Query 1157 SFRPTFENL 1165
RP F L
Sbjct 891 EQRPPFAQL 899
Score = 77.8 bits (190), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 76/270 (28%), Positives = 121/270 (45%), Gaps = 44/270 (16%)
Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+G L V +K+L P A F + +MS++ ++ + GVCV+ M+T+Y+E
Sbjct 644 KGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYME 703
Query 692 HGPLDVWLR---------------RERGHVP-MAWKMV--VAQQLASALSYLENKNLVHG 733
+G L+ +L E P +++ M+ V Q+AS + YL N VH
Sbjct 704 NGDLNQFLSARQLENKATQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHR 763
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGG 787
++ RN L+ G + IK++D G+ + + V I W+A EC+ G
Sbjct 764 DLATRNCLV-------GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG 816
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-----EHFYQRQHRLP----EPSC 838
+TA D W FG TL E+ + + E+ F++ Q R P+C
Sbjct 817 --KFTTASDVWAFGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPAC 874
Query 839 PQ-LATLTSQCLTYEPTQRPSFRTILRDLT 867
PQ L L +C + EP QRP F + R L
Sbjct 875 PQTLYELMLRCWSREPEQRPPFAQLHRFLA 904
>sp|P54764|EPHA4_HUMAN Ephrin type-A receptor 4 OS=Homo sapiens
OX=9606 GN=EPHA4 PE=1 SV=1
Length=986
Score = 137 bits (346), Expect = 1e-31, Method: Compositional matrix adjust.
Identities = 78/245 (32%), Positives = 129/245 (53%), Gaps = 18/245 (7%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VA+K LKA + R + E I+ H +II +G K + ++ EY+ GSL
Sbjct 650 VAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKC--KPVMIITEYMENGSL 707
Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L ++ + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFG+
Sbjct 708 DAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGM 767
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
++ + + E G P+ W APE + KF ASDVWS+G+ ++E++++ + P
Sbjct 768 SRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY---GERP 824
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
M+ + + +E G RLP P CP ++ LM +CW+ E S RP F
Sbjct 825 -----------YWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQ 873
Query 1165 LIPIL 1169
++ +L
Sbjct 874 IVNML 878
Score = 94.4 bits (233), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 81/295 (27%), Positives = 133/295 (45%), Gaps = 33/295 (11%)
Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
VPG+ +E+ V +K L + D F AS+M Q H ++ + GV + +++
Sbjct 642 VPGK---REICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMII 698
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TEY+E+G LD +LR+ G + + + + + S + YL + + VH ++ RNIL+
Sbjct 699 TEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILV---- 754
Query 747 LAEGTSPFIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWG 799
++ K+SD G+ E R +IP W APE + ++A D W
Sbjct 755 ---NSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAI--AYRKFTSASDVWS 809
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRP 857
+G + E+ GE P S + + +RLP P CP L L C E + RP
Sbjct 810 YGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRP 869
Query 858 SFRTILRDLTRL--QPHNLADVLT---------VNPDSPASDPTVFHKRYLKKIR 901
F I+ L +L P++L T ++P SP V +L+ I+
Sbjct 870 KFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVSVGDWLQAIK 924
>sp|P29322|EPHA8_HUMAN Ephrin type-A receptor 8 OS=Homo sapiens
OX=9606 GN=EPHA8 PE=1 SV=2
Length=1005
Score = 137 bits (346), Expect = 1e-31, Method: Compositional matrix adjust.
Identities = 82/248 (33%), Positives = 128/248 (52%), Gaps = 18/248 (7%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VA+KALKA + R + E I+ H +II+ +G +G ++ +V EY+ GSL
Sbjct 664 VAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVT-RGRLAM-IVTEYMENGSL 721
Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L H + QL+ + + GM YL Y+HRDLAARNVL+D++ + K+ DFGL
Sbjct 722 DTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGL 781
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
++ + + + G P+ W APE + F ASDVWSFGV ++E+L + +
Sbjct 782 SRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGER---- 837
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
MT + +E G RLP P CP ++ LM +CW + + RP F
Sbjct 838 ----------PYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQ 887
Query 1165 LIPILKTV 1172
++ +L +
Sbjct 888 IVSVLDAL 895
Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 87/329 (26%), Positives = 137/329 (42%), Gaps = 52/329 (16%)
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
R R+ R + S++ ++ +G G V GRLRV G D
Sbjct 621 RAGRSFTREIEASRIHIEKI----------IGSGDSGEVCYGRLRVPGQRD--------- 661
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPEN 683
VP V +K L + + F AS+M Q H ++ + GV RG
Sbjct 662 ---VP---------VAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLA 709
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
++VTEY+E+G LD +LR G + + + + + + + YL + VH ++ RN+L+
Sbjct 710 MIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLV- 768
Query 744 RLGLAEGTSPFIKLSDPGVGL-------GALSREERVERIPWLAPECLPGGANSLSTAMD 796
++ K+SD G+ A + I W APE + + S+A D
Sbjct 769 ------DSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAI--AFRTFSSASD 820
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPT 854
W FG + E+ GE P + + + + +RLP P CP L L C +
Sbjct 821 VWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRA 880
Query 855 QRPSFRTILRDLTRL--QPHNLADVLTVN 881
QRP F I+ L L P +L TV+
Sbjct 881 QRPRFSQIVSVLDALIRSPESLRATATVS 909
>sp|P00529|ROS_AVISU Tyrosine-protein kinase transforming protein
ros OS=UR2 avian sarcoma virus OX=354090 GN=V-ROS PE=3 SV=1
Length=402
Score = 132 bits (331), Expect = 1e-31, Method: Compositional matrix adjust.
Identities = 97/278 (35%), Positives = 135/278 (49%), Gaps = 37/278 (13%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG G FG+V D DG+GE VAVK LK Q +S + +E ++ H HI+
Sbjct 104 LGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMSKFDHPHIL 163
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQLLLFAQQICEG 1010
K G C + L++E + G L YL P ++ + IC+G
Sbjct 164 KLLGVCLLNEPQ--YLILELMEGGDLLSYLRGARKQKFQSPLLTLTDLLDICL--DICKG 219
Query 1011 MAYLHAQHYIHRDLAARNVLLDN------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
YL +IHRDLAARN L+ R+VKIGDFGLA+ + + ++YYR R +G P
Sbjct 220 CVYLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYK-NDYYRKRGEGLLP 278
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
V W APE L + F SDVW+FGV ++E LT Q P ++ + +
Sbjct 279 VRWMAPESLIDGVFTNHSDVWAFGVLVWETLT---LGQQPYPG-----------LSNIEV 324
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
+ G RL P+ CP ++ LM CW + RPTF
Sbjct 325 LHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTF 362
Score = 74.7 bits (182), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 74/294 (25%), Positives = 116/294 (39%), Gaps = 42/294 (14%)
Query 595 LGQGTRTNVYEGR---LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651
LG G VYEG + +GSG E RV +K L D
Sbjct 104 LGSGAFGEVYEGTALDILADGSG---------------------ESRVAVKTLKRGATDQ 142
Query 652 ALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH----- 705
+ F + A LMS+ H H+ + GVC+ ++ E +E G L +LR R
Sbjct 143 EKSEFLKEAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRGARKQKFQSP 202
Query 706 -VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + + + + YLE +H ++ RN L++ S +K+ D G+
Sbjct 203 LLTLTDLLDICLDICKGCVYLEKMRFIHRDLAARNCLVSEKQYGS-CSRVVKIGDFGLAR 261
Query 765 GALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ +R + W+APE L G + D W FG + E G+ P
Sbjct 262 DIYKNDYYRKRGEGLLPVRWMAPESLIDGV--FTNHSDVWAFGVLVWETLTLGQQPYPGL 319
Query 819 SPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
S E H + RL P +CP + L ++C +P RP+F I L ++
Sbjct 320 SNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEIR 373
>sp|Q61006|MUSK_MOUSE Muscle, skeletal receptor tyrosine-protein
kinase OS=Mus musculus OX=10090 GN=Musk PE=1 SV=1
Length=868
Score = 137 bits (345), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 89/318 (28%), Positives = 154/318 (48%), Gaps = 53/318 (17%)
Query 892 FHKRYLKKIRDLGEGHFGKV------SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
+ + ++ +RD+GEG FG+V L Y+P MVAVK LK + ++ ++
Sbjct 569 YPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFT-----MVAVKMLKEEASADMQADFQ 623
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------- 994
+E ++ + +I+K G C K + L+ EY+ G L ++L S
Sbjct 624 REAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSD 681
Query 995 --------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040
+ A+ L A+Q+ GMAYL + ++HRDLA RN L+ +VKI
Sbjct 682 LSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGETMVVKIA 741
Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100
DFGL++ + +YY+ + P+ W PE + ++ SDVW++GV L+E+ ++
Sbjct 742 DFGLSRNIYSA-DYYKADGNDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSY--- 797
Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
G+A ++ + G L P+ CP E+Y+LM+ CW + RP
Sbjct 798 ------GLQPYYGMAHEEVIY-----YVRDGNILACPENCPLELYNLMRLCWSKLPADRP 846
Query 1161 TFENLIPILKTVHEKYQG 1178
+F ++ IL+ + E+ +G
Sbjct 847 SFCSIHRILQRMCERAEG 864
Score = 77.4 bits (189), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 67/263 (25%), Positives = 120/263 (46%), Gaps = 41/263 (16%)
Query 639 VVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V +K+L + + D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+
Sbjct 605 VAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNE 664
Query 698 WLRRERGH-----------------------VPMAWKMVVAQQLASALSYLENKNLVHGN 734
+LR H + A ++ +A+Q+A+ ++YL + VH +
Sbjct 665 FLRSMSPHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRD 724
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGA 788
+ RN L+ G + +K++D G+ S + + + IP W+ PE +
Sbjct 725 LATRNCLV-------GETMVVKIADFGLSRNIYSADYYKADGNDAIPIRWMPPESI--FY 775
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTS 846
N +T D W +G L EI G P + E ++ + + L P +CP +L L
Sbjct 776 NRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILACPENCPLELYNLMR 835
Query 847 QCLTYEPTQRPSFRTILRDLTRL 869
C + P RPSF +I R L R+
Sbjct 836 LCWSKLPADRPSFCSIHRILQRM 858
>sp|Q91694|EPA4B_XENLA Ephrin type-A receptor 4-B OS=Xenopus laevis
OX=8355 GN=epha4-b PE=2 SV=1
Length=985
Score = 137 bits (345), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 89/294 (30%), Positives = 148/294 (50%), Gaps = 31/294 (11%)
Query 888 DPTVFHKRYLKKI--------RDLGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCG 937
DP + + K+I + +G G FG+V C G E+ VA+K LKA
Sbjct 603 DPNQAVREFAKEIDASCIKIEKVIGVGEFGEV---CSGRLKVPGKREIYVAIKTLKAGYT 659
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995
+ R + E I+ H +II +G K + ++ EY+ GSL +L ++
Sbjct 660 DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKC--KPVMIITEYMENGSLDAFLRKNDGRF 717
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFG+++ + + E
Sbjct 718 TVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAA 777
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
G P+ W APE + KF ASDVWS+G+ ++E++++ + P
Sbjct 778 YTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY---GERP----------- 823
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
M+ + + +E G RLP P CP ++ LM +CW+ + S RP F ++ +L
Sbjct 824 YWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKDRSDRPKFGQIVSML 877
Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 73/259 (28%), Positives = 121/259 (47%), Gaps = 24/259 (9%)
Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
VPG+ +E+ V +K L + D F AS+M Q H ++ + GV + +++
Sbjct 641 VPGK---REIYVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMII 697
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TEY+E+G LD +LR+ G + + + + + S + YL + + VH ++ RNIL+
Sbjct 698 TEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILV---- 753
Query 747 LAEGTSPFIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWG 799
++ K+SD G+ E R +IP W APE + ++A D W
Sbjct 754 ---NSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAI--AYRKFTSASDVWS 808
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRP 857
+G + E+ GE P S + + +RLP P CP L L C + + RP
Sbjct 809 YGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKDRSDRP 868
Query 858 SFRTILRDLTRL--QPHNL 874
F I+ L +L P++L
Sbjct 869 KFGQIVSMLDKLIRNPNSL 887
>sp|H2KZU7|SVH2_CAEEL Tyrosine-protein kinase receptor svh-2 OS=Caenorhabditis
elegans OX=6239 GN=svh-2 PE=1 SV=1
Length=1086
Score = 137 bits (345), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 94/290 (32%), Positives = 142/290 (49%), Gaps = 20/290 (7%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
F + K+ +G+GH+G V Y P+ E V K LK S + +E +
Sbjct 730 FKNLRVDKLDPIGQGHYGVVYKAMYSPSK-SLEEKVVCKYLKEG----KISEFYEEARTM 784
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICE 1009
H +I+K G D ++ EY+ G L+ ++ ++I + L FA I +
Sbjct 785 SEFDHPNILKLIGVALDDSSHLPIIITEYMAKGDLKSFIENVENTIKMRDLFEFAFDIAK 844
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
GM Y+H++ +IHRDLA RN LLD VKI DFGL + V E Y + D PV W+
Sbjct 845 GMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERDLPVRWFP 904
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE + E F SD+WSFGV ++EL T +P + I I + L+ +E
Sbjct 905 PE-ISEQGFGITSDIWSFGVVIWELFTR---GSTPYSNMASWILI----LPWLKESET-- 954
Query 1130 RGERLPRPDKCPCEVY-HLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
RL +P CP ++Y +M CW+ + RP F +L+ I+ V + +G
Sbjct 955 --NRLRKPPYCPEKLYTDVMLACWKANPAERPQFSDLVTIIPNVVKYMEG 1002
Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 57/236 (24%), Positives = 90/236 (38%), Gaps = 35/236 (15%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN--IMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
FYE A MS+ H ++ + GV + + I++TEY+ G L ++ + M
Sbjct 777 FYEEARTMSEFDHPNILKLIGVALDDSSHLPIIITEYMAKGDLKSFIENVENTIKMRDLF 836
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPGVGL 764
A +A ++Y+ +K +H ++ RN LL A GL +L
Sbjct 837 EFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETEL------- 889
Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS----- 819
+ ER + W PE G D W FG + E+ G P + +
Sbjct 890 -YVQMHERDLPVRWFPPEISEQG---FGITSDIWSFGVVIWELFTRGSTPYSNMASWILI 945
Query 820 -PSEKEHFYQRQHRLPEPSCPQ--LATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
P KE R + P CP+ + C P +RP F DL + P+
Sbjct 946 LPWLKESETNRLRK--PPYCPEKLYTDVMLACWKANPAERPQF----SDLVTIIPN 995
>sp|P08630|BTKL_DROME Tyrosine-protein kinase Btk OS=Drosophila
melanogaster OX=7227 GN=Btk PE=2 SV=2
Length=786
Score = 136 bits (343), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 104/323 (32%), Positives = 152/323 (47%), Gaps = 40/323 (12%)
Query 865 DLTRLQPHN---LADVLTVNP-DSP-------ASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
DL HN LA L +P D P + D H L + +LG G FG V
Sbjct 483 DLINYHRHNSGGLACRLKSSPCDRPVPPTAGLSHDKWEIHPMELMLMEELGSGQFGVVRR 542
Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
+ + D AVK +K G + +E ++ L H ++++ G C +
Sbjct 543 GKWRGSID-----TAVKMMKE--GTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKH--RP 593
Query 974 LQLVMEYVPLGSLRDYLPRHS---IGLAQLLL-FAQQICEGMAYLHAQHYIHRDLAARNV 1029
+ +V EY+ GSL +YL RH IG LLL Q+ +GM YL +YIHRDLAARN
Sbjct 594 IYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNC 653
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
L+ ++ +VK+ DFGLA+ V + + Y P+ W PE L +F SDVW++GV
Sbjct 654 LVGSENVVKVADFGLARYVLD--DQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGV 711
Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149
++E+ T C + G++ + E ++RG L +P C E+Y +MK
Sbjct 712 LMWEIFT-CGK-------------MPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMK 757
Query 1150 NCWETEASFRPTFENLIPILKTV 1172
CW RP F L+ L V
Sbjct 758 LCWSHGPEERPAFRVLMDQLALV 780
Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 66/233 (28%), Positives = 110/233 (47%), Gaps = 23/233 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER----GHVPMAW 710
F E A +M+++ H +L ++GVC + +VTEY++HG L +LRR G++ +
Sbjct 566 FIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLL 625
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
M + Q++ ++YLE N +H ++ RN L+ G+ +K++D G+ L +
Sbjct 626 DMCI--QVSKGMTYLERHNYIHRDLAARNCLV-------GSENVVKVADFGLARYVLDDQ 676
Query 771 ERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
I W PE L S+ D W +G + EI G+ P +E
Sbjct 677 YTSSGGTKFPIKWAPPEVL--NYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVE 734
Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
QR L +P SC ++ + C ++ P +RP+FR +L D L L D
Sbjct 735 RVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFR-VLMDQLALVAQTLTD 786
>sp|Q54I36|PYK3_DICDI Dual specificity protein kinase pyk3 OS=Dictyostelium
discoideum OX=44689 GN=pyk3 PE=1 SV=1
Length=1338
Score = 137 bits (345), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 130/547 (24%), Positives = 234/547 (43%), Gaps = 71/547 (13%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S + + H +L + G C ++I+ + L + R+ + MA + +++ +A
Sbjct 809 SKYTMIQHKNLGLLVGWC---GDSIIFESFKGMNSLHDLIHRDGLKIDMALFIKISKDIA 865
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL 779
S + L +K++ HGN+ R+I L R + + + P + +D L + E R ++
Sbjct 866 SVMGLLHSKDVAHGNLTSRSIYLDRFQIVKVSFPKLNATD----LNNPAIEPR-----YM 916
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ---SRSPSEKEHFYQRQHRLPEP 836
APE + +S ++D + + L E P + S + K + + ++P
Sbjct 917 APEMTRMEEDQISCSIDVYAYAFVLWE-ALTSHLPFRKFNDISVAAKVAYENLRPKIP-T 974
Query 837 SCPQLA-TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD----VLTVNPDSPASDPTV 891
SCP + L ++C P+ RP+F IL+ L+ + ++N D
Sbjct 975 SCPLIIRKLINRCWAPLPSDRPTFNDILKLFDHLEGKLFFSSPGILWSLNNDQEVERELQ 1034
Query 892 FHKRY-----------------LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+R+ + + +G G F V L ++ G VA+K LK
Sbjct 1035 KKERFNEITEFLRGKKEIKFDEVAIVEKVGAGSFANVFLGIWN------GYKVAIKILKN 1088
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994
+ + + +E+ L +H +++ + G C D + EY+ GSL D L
Sbjct 1089 E-SISNDEKFIKEVSSLIKSHHPNVVTFMGACIDPP----CIFTEYLQGGSLYDVLHIQK 1143
Query 995 IGLAQLLLFA--QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
I L L+++ + GM +LH+ +HRDL ++N+LLD + +KI DFGLA + +
Sbjct 1144 IKLNPLMMYKMIHDLSLGMEHLHSIQMLHRDLTSKNILLDEFKNIKIADFGLATTLSDD- 1202
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
+ G + W +PE K + DV+SFG+ +YE+ T F L
Sbjct 1203 ----MTLSGITNPRWRSPELTKGLVYNEKVDVYSFGLVVYEIYTG-------KIPFEGLD 1251
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
G A R P CP + L+ CW ++ S RP+F ++ L+T+
Sbjct 1252 GTASAAKAAF-------ENYRPAIPPDCPVSLRKLITKCWASDPSQRPSFTEILTELETM 1304
Query 1173 HEKYQGQ 1179
K+ Q
Sbjct 1305 KSKFIKQ 1311
Score = 67.0 bits (162), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 67/260 (26%), Positives = 120/260 (46%), Gaps = 30/260 (12%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-D 696
+V +K+L F + S + + H ++ G C+ P + TEY++ G L D
Sbjct 1080 KVAIKILKNESISNDEKFIKEVSSLIKSHHPNVVTFMGACIDPP--CIFTEYLQGGSLYD 1137
Query 697 VW-LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
V +++ + + M +KM+ L+ + +L + ++H ++ +NILL I
Sbjct 1138 VLHIQKIKLNPLMMYKMI--HDLSLGMEHLHSIQMLHRDLTSKNILLDEFK-------NI 1188
Query 756 KLSDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
K++D G+ LS + + I W +PE G + +D + FG + EI + G+
Sbjct 1189 KIADFGLA-TTLSDDMTLSGITNPRWRSPELTKGLV--YNEKVDVYSFGLVVYEI-YTGK 1244
Query 813 AP---LQSRSPSEKEHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTR 868
P L + + K F + +P P CP L L ++C +P+QRPSF IL +L
Sbjct 1245 IPFEGLDGTASAAKAAFENYRPAIP-PDCPVSLRKLITKCWASDPSQRPSFTEILTELET 1303
Query 869 LQPH-----NLADVLTVNPD 883
++ + + L NPD
Sbjct 1304 MKSKFIKQLSFLNDLIQNPD 1323
Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 52/210 (25%), Positives = 91/210 (43%), Gaps = 35/210 (17%)
Query 983 LGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040
+ SL D + R I +A + ++ I M LH++ H +L +R++ LD ++VK+
Sbjct 838 MNSLHDLIHRDGLKIDMALFIKISKDIASVMGLLHSKDVAHGNLTSRSIYLDRFQIVKVS 897
Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVF---WYAPEC--LKEYKFYYASDVWSFGVTLYELL 1095
F A D ++P + APE ++E + + DV+++ L+E L
Sbjct 898 -FPKLNAT-----------DLNNPAIEPRYMAPEMTRMEEDQISCSIDVYAYAFVLWEAL 945
Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR-PDKCPCEVYHLMKNCWET 1154
T S P KF ++ A+ LR P+ P CP + L+ CW
Sbjct 946 T----SHLPFRKFNDISVAAKVAYENLR-----------PKIPTSCPLIIRKLINRCWAP 990
Query 1155 EASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
S RPTF +++ + + K +P +
Sbjct 991 LPSDRPTFNDILKLFDHLEGKLFFSSPGIL 1020
>sp|P15127|INSR_RAT Insulin receptor OS=Rattus norvegicus OX=10116
GN=Insr PE=1 SV=1
Length=1383
Score = 137 bits (345), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 91/285 (32%), Positives = 148/285 (52%), Gaps = 33/285 (12%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+R+LG+G FG V Y + + GE+ VAVK + + R + E +++
Sbjct 1027 LRELGQGSFGMV--YEGNAKDIIKGEVETRVAVKTVNESASLRERIEFLNEASVMKGFTC 1084
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------PRHSIGLAQLLLFAQ 1005
H+++ G +G+ +L +VME + G L+ +L R L +++
Sbjct 1085 HHVVRLLGVVS-KGQPTL-VVMELMAHGDLKSHLRSLRPDAENNPGRPPPTLQEMIQMTA 1142
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
+I +GMAYL+A+ ++HRDLAARN ++ +D VKIGDFG+ + + E +YYR G PV
Sbjct 1143 EIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYET-DYYRKGGKGLLPV 1201
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
W +PE LK+ F +SD+WSFGV L+E+ + + G++ Q +
Sbjct 1202 RWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQ---------GLSNEQ-----VL 1247
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ + G L PD CP + LM+ CW+ RPTF ++ +LK
Sbjct 1248 KFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLK 1292
Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 79/301 (26%), Positives = 127/301 (42%), Gaps = 46/301 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +++IT L LGQG+ VYEG + D +G++ E RV +K
Sbjct 1019 VPREKITLLRELGQGSFGMVYEGNAK-----DIIKGEV--------------ETRVAVKT 1059
Query 644 LDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
++ S + F AS+M + H+ + GV +G ++V E + HG L LR
Sbjct 1060 VNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSL 1119
Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
R P +M+ + ++A ++YL K VH ++ RN ++A
Sbjct 1120 RPDAENNPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAH-------DF 1172
Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+ D G+ + + + + W++PE L G + + D W FG L EI
Sbjct 1173 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTASSDMWSFGVVLWEI 1230
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRD 865
E P Q S + F L P +CP+ L L C + P RP+F I+
Sbjct 1231 TSLAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNL 1290
Query 866 L 866
L
Sbjct 1291 L 1291
>sp|P15208|INSR_MOUSE Insulin receptor OS=Mus musculus OX=10090
GN=Insr PE=1 SV=2
Length=1372
Score = 137 bits (345), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 90/283 (32%), Positives = 144/283 (51%), Gaps = 29/283 (10%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+R+LG+G FG V G E VAVK + + R + E +++ H
Sbjct 1016 LRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHH 1075
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------PRHSIGLAQLLLFAQQI 1007
+++ G +G+ +L +VME + G L+ +L R L +++ +I
Sbjct 1076 VVRLLGVVS-KGQPTL-VVMELMAHGDLKSHLRSLRPDAENNPGRPPPTLQEMIQMTAEI 1133
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+GMAYL+A+ ++HRDLAARN ++ +D VKIGDFG+ + + E +YYR G PV W
Sbjct 1134 ADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYET-DYYRKGGKGLLPVRW 1192
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
+PE LK+ F +SD+WSFGV L+E+ + + G++ Q + +
Sbjct 1193 MSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQ---------GLSNEQ-----VLKF 1238
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ G L PD CP + LM+ CW+ RPTF ++ +LK
Sbjct 1239 VMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLK 1281
Score = 81.6 bits (200), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 78/301 (26%), Positives = 124/301 (41%), Gaps = 46/301 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +++IT L LGQG+ VYEG + G+ E RV +K
Sbjct 1008 VPREKITLLRELGQGSFGMVYEGNAKDIIKGE-------------------AETRVAVKT 1048
Query 644 LDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
++ S + F AS+M + H+ + GV +G ++V E + HG L LR
Sbjct 1049 VNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSL 1108
Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
R P +M+ + ++A ++YL K VH ++ RN ++A
Sbjct 1109 RPDAENNPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAH-------DF 1161
Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+ D G+ + + + + W++PE L G + + D W FG L EI
Sbjct 1162 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTASSDMWSFGVVLWEI 1219
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRD 865
E P Q S + F L P +CP+ L L C + P RP+F I+
Sbjct 1220 TSLAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNL 1279
Query 866 L 866
L
Sbjct 1280 L 1280
>sp|P42687|SPK1_GIRTI Tyrosine-protein kinase SPK-1 OS=Girardia
tigrina OX=6162 PE=2 SV=1
Length=497
Score = 133 bits (334), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 87/272 (32%), Positives = 134/272 (49%), Gaps = 31/272 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ ++G G FG V + G VA K L++ R + E I+ L H I
Sbjct 223 LNEIGRGFFGSVHRAKW-----GRSYEVAAKMLQS--SKAEREKFVLEAKIMHKLRHRKI 275
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHA 1016
++ G C + + + +++EY+ GSL++YL L Q++ +I EGMAYL +
Sbjct 276 VELLGVCTEPQDMPMLIIVEYMKNGSLKEYLKTPDGKKTNLNQMVHMMAEISEGMAYLES 335
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ +HRDL A N+L+ ND K+ DFGL + + +G + ++ P W APE K
Sbjct 336 EKVVHRDLRADNILVANDLTRKVADFGLTE-LTDGSLGDQEKKTLRFPYKWTAPEAAKSK 394
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
F SDVWS+G+ ++E+LT SS P E+I E + +G R+P
Sbjct 395 VFTSKSDVWSYGIVMFEILTWA-SSPYPDIPAKEVI-------------EKVSKGYRMPN 440
Query 1137 PDK------CPCEVYHLMKNCWETEASFRPTF 1162
P+K CP E+Y +M CW+ RPTF
Sbjct 441 PEKFITGVCCPDEIYKIMIWCWDANPEKRPTF 472
Score = 73.9 bits (180), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 64/264 (24%), Positives = 119/264 (45%), Gaps = 29/264 (11%)
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN---IMVTEYV 690
G+ V K+L S + F A +M ++ H + + GVC P++ +++ EY+
Sbjct 240 GRSYEVAAKMLQSSKAERE-KFVLEAKIMHKLRHRKIVELLGVCTE-PQDMPMLIIVEYM 297
Query 691 EHGPLDVWLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
++G L +L+ G +MV + +++ ++YLE++ +VH ++ NIL+A L
Sbjct 298 KNGSLKEYLKTPDGKKTNLNQMVHMMAEISEGMAYLESEKVVHRDLRADNILVAN-DLTR 356
Query 750 GTSPF--IKLSDPGVGLGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLL 805
+ F +L+D +G +E++ R P W APE + ++ D W +G +
Sbjct 357 KVADFGLTELTDGSLG----DQEKKTLRFPYKWTAPEA--AKSKVFTSKSDVWSYGIVMF 410
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------CP-QLATLTSQCLTYEPTQRP 857
EI +P E + +R+P P CP ++ + C P +RP
Sbjct 411 EILTWASSPYPDIPAKEVIEKVSKGYRMPNPEKFITGVCCPDEIYKIMIWCWDANPEKRP 470
Query 858 SFRTILRDLTRLQPHNLADVLTVN 881
+F + + L + D LT N
Sbjct 471 TFLVLQEKMDLL----IVDTLTNN 490
>sp|P57097|MERTK_RAT Tyrosine-protein kinase Mer OS=Rattus norvegicus
OX=10116 GN=Mertk PE=2 SV=1
Length=994
Score = 136 bits (343), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 93/288 (32%), Positives = 140/288 (49%), Gaps = 29/288 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEI 948
V + L + LGEG FG V + DGT + VAVK +K D + + E
Sbjct 575 VVVDRNLLILGKVLGEGEFGSV-MEGNLKQEDGTSQKVAVKTMKLDNFSLREIEEFLSEA 633
Query 949 DILRTLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGSLRDYL--------PRHSIGL 997
++ H ++I+ G C QG +++ ++ G L +L P+ SI L
Sbjct 634 ACMKDFNHPNVIRLLGVCIELSSQGIPKPMVILPFMKYGDLHTFLLYSRIESVPK-SIPL 692
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
LL F I +GM YL +++++HRDLAARN +L +D V + DFGL+K + G +YYR
Sbjct 693 QTLLKFMVDIAQGMEYLSSRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQ 751
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
PV W A E L + + SDVW+FGVT++E+ T G+
Sbjct 752 GRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATR---------GMTPYPGVQNH 802
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+M + L G RL +P+ C ++Y +M +CW + RPTF L
Sbjct 803 EM-----YDYLLHGHRLKQPEDCLDDLYEIMYSCWSADPLDRPTFSVL 845
Score = 69.7 bits (169), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 73/309 (24%), Positives = 130/309 (42%), Gaps = 38/309 (12%)
Query 606 GRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI--ALAFYETASLM 662
G++ EG G EG + ED G +V +K + + + F A+ M
Sbjct 585 GKVLGEGEFGSVMEGNLKQED--------GTSQKVAVKTMKLDNFSLREIEEFLSEAACM 636
Query 663 SQVSHTHLAFVHGVCVR-----GPENIMVTEYVEHGPLDVWLRRER-----GHVPMAWKM 712
+H ++ + GVC+ P+ +++ ++++G L +L R +P+ +
Sbjct 637 KDFNHPNVIRLLGVCIELSSQGIPKPMVILPFMKYGDLHTFLLYSRIESVPKSIPLQTLL 696
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
+A + YL ++N +H ++ RN +L R + + F LS + G R+ R
Sbjct 697 KFMVDIAQGMEYLSSRNFLHRDLAARNCML-RDDMTVCVADF-GLSKK-IYSGDYYRQGR 753
Query 773 VERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
+ ++P W+A E L ++ D W FG T+ EI G P E +
Sbjct 754 IAKMPVKWIAIESL--ADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLHG 811
Query 831 HRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASD 888
HRL PE L + C + +P RP+F + RLQ L++ L PD+ +
Sbjct 812 HRLKQPEDCLDDLYEIMYSCWSADPLDRPTFSVL-----RLQLEKLSESL---PDAQDKE 863
Query 889 PTVFHKRYL 897
++ L
Sbjct 864 SIIYINTQL 872
>sp|Q63132|ROS1_RAT Proto-oncogene tyrosine-protein kinase ROS
OS=Rattus norvegicus OX=10116 GN=Ros1 PE=2 SV=1
Length=2338
Score = 137 bits (345), Expect = 4e-31, Method: Compositional matrix adjust.
Identities = 96/261 (37%), Positives = 135/261 (52%), Gaps = 37/261 (14%)
Query 922 GTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC---EDQGEKSLQLV 977
G+GE+ VAVK LK Q + + +E ++ H +I+K G C E Q ++
Sbjct 1963 GSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLSEPQ-----YII 2017
Query 978 MEYVPLGSLRDYLPRHS--------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029
+E + G L YL + + LA L+ I +G YL H+IHRDLAARN
Sbjct 2018 LELMEGGDLLSYLRKARGTTLSGPLLTLADLVELCVDISKGCVYLEQMHFIHRDLAARNC 2077
Query 1030 LLD-----NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084
L+ + R+VKIGDFGLA+ + + H+YYR R +G PV W APE L + F SDV
Sbjct 2078 LVSVKDYTSPRVVKIGDFGLAREIYK-HDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDV 2136
Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144
WSFG+ ++E+LT Q P A + VL ++ G RL P CP ++
Sbjct 2137 WSFGILVWEILTL--GHQPYP---------AHSNLDVLN---YVQAGGRLEPPRNCPDDL 2182
Query 1145 YHLMKNCWETEASFRPTFENL 1165
++LM CW E RPTF N+
Sbjct 2183 WNLMFRCWAQEPDQRPTFYNI 2203
Score = 87.0 bits (214), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 80/289 (28%), Positives = 132/289 (46%), Gaps = 26/289 (9%)
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAF 672
G+ EG D + GR G E++V +K L D + F + A LMS+ +H ++
Sbjct 1949 GEVYEGTAVD----ILGRGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILK 2003
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH------VPMAWKMVVAQQLASALSYLE 726
GVC+ ++ E +E G L +LR+ RG + +A + + ++ YLE
Sbjct 2004 QLGVCLLSEPQYIILELMEGGDLLSYLRKARGTTLSGPLLTLADLVELCVDISKGCVYLE 2063
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSP-FIKLSDPGVGLGALSREERVER------IPWL 779
+ +H ++ RN L++ + + TSP +K+ D G+ + +R + W+
Sbjct 2064 QMHFIHRDLAARNCLVS---VKDYTSPRVVKIGDFGLAREIYKHDYYRKRGEGLLPVRWM 2120
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838
APE L G ++ D W FG + EI G P + S + ++ Q RL P +C
Sbjct 2121 APENLMDGI--FTSQSDVWSFGILVWEILTLGHQPYPAHSNLDVLNYVQAGGRLEPPRNC 2178
Query 839 P-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
P L L +C EP QRP+F I L + +L +V +PA
Sbjct 2179 PDDLWNLMFRCWAQEPDQRPTFYNIQDQLQLFRNVSLNNVSHCGQAAPA 2227
>sp|Q64716|INSRR_RAT Insulin receptor-related protein OS=Rattus
norvegicus OX=10116 GN=Insrr PE=1 SV=3
Length=1300
Score = 136 bits (343), Expect = 4e-31, Method: Compositional matrix adjust.
Identities = 94/283 (33%), Positives = 147/283 (52%), Gaps = 37/283 (13%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDG--TGEM---VAVKALKADCGPQHRSGWKQEIDILRTL 954
IR+LG+G FG V Y+ G GE VA+K + + R + +E +++
Sbjct 982 IRELGQGSFGMV----YEGLARGLEAGEESTPVALKTVNELASARERVEFLKEASVMKAF 1037
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQ-----LLLF 1003
H+++ G QG+ +L ++ME + G L+ +L ++ GL Q ++
Sbjct 1038 KCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSHLRSLRPEAENNPGLPQPALSDMIQM 1095
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
A +I +GMAYL A+ ++HRDLAARN ++ D VKIGDFG+ + V E +YYR G
Sbjct 1096 AGEIADGMAYLAAKKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYE-TDYYRKGGKGLL 1154
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
PV W APE LK+ F SDVWSFGV L+E++T + G++ Q+
Sbjct 1155 PVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQ---------GLSNEQV---- 1201
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ + G L + CP ++ LM+ CW+ RPTF +++
Sbjct 1202 -LKFVMDGGVLEEQEDCPIQLQELMRRCWQHTPRLRPTFVHIL 1243
Score = 73.9 bits (180), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 76/298 (26%), Positives = 121/298 (41%), Gaps = 46/298 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLR-VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
V +++I + LGQG+ VYEG R +E + + + L R+R
Sbjct 974 VPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASARER--------- 1024
Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+ F + AS+M H+ + GV +G +++ E + G L LR
Sbjct 1025 ----------VEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSL 1074
Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
R P M+ +A ++A ++YL K VH ++ RN ++++
Sbjct 1075 RPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQ-------DF 1127
Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+ D G+ + + + + W+APE L G +T D W FG L EI
Sbjct 1128 TVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGI--FTTHSDVWSFGVVLWEI 1185
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSFRTIL 863
E P Q S + F L E CP QL L +C + P RP+F IL
Sbjct 1186 VTLAEQPYQGLSNEQVLKFVMDGGVLEEQEDCPIQLQELMRRCWQHTPRLRPTFVHIL 1243
>sp|Q06187|BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo sapiens
OX=9606 GN=BTK PE=1 SV=3
Length=659
Score = 134 bits (338), Expect = 4e-31, Method: Compositional matrix adjust.
Identities = 89/279 (32%), Positives = 140/279 (50%), Gaps = 28/279 (10%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+++LG G FG V + D VA+K +K G + +E ++ L HE +
Sbjct 405 LKELGTGQFGVVKYGKWRGQYD-----VAIKMIKE--GSMSEDEFIEEAKVMMNLSHEKL 457
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ 1017
++ G C Q + + ++ EY+ G L +YL RH QLL + +CE M YL ++
Sbjct 458 VQLYGVCTKQ--RPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESK 515
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
++HRDLAARN L+++ +VK+ DFGL++ V + Y PV W PE L K
Sbjct 516 QFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDE--YTSSVGSKFPVRWSPPEVLMYSK 573
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SD+W+FGV ++E+ + L + + T E + +G RL RP
Sbjct 574 FSSKSDIWAFGVLMWEIYS--------------LGKMPYERFTNSETAEHIAQGLRLYRP 619
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP-ILKTVHEK 1175
+VY +M +CW +A RPTF+ L+ IL + E+
Sbjct 620 HLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 658
Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 81/317 (26%), Positives = 137/317 (43%), Gaps = 55/317 (17%)
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP-----E 617
+ + + +P T L S+ +D K++T L LG G V G+ R G D +
Sbjct 377 VSQQNKNAPSTAGLGYGSWE-IDPKDLTFLKELGTGQFGVVKYGKWR--GQYDVAIKMIK 433
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
EG M +++ F E A +M +SH L ++GVC
Sbjct 434 EGSMSEDE-----------------------------FIEEAKVMMNLSHEKLVQLYGVC 464
Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737
+ ++TEY+ +G L +LR R + + + + A+ YLE+K +H ++
Sbjct 465 TKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAA 524
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV---ERIP--WLAPECLPGGANSLS 792
RN L+ G+ +K+SD G+ L E + P W PE L + S
Sbjct 525 RNCLVNDQGV-------VKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVL--MYSKFS 575
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQ--RQHRLPEPSCPQLATLTSQCL 849
+ D W FG + EI G+ P + + SE EH Q R +R P + ++ T+ C
Sbjct 576 SKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYR-PHLASEKVYTIMYSCW 634
Query 850 TYEPTQRPSFRTILRDL 866
+ +RP+F+ +L ++
Sbjct 635 HEKADERPTFKILLSNI 651
>sp|P13368|7LESS_DROME Protein sevenless OS=Drosophila melanogaster
OX=7227 GN=sev PE=1 SV=2
Length=2554
Score = 137 bits (344), Expect = 4e-31, Method: Compositional matrix adjust.
Identities = 94/295 (32%), Positives = 139/295 (47%), Gaps = 38/295 (13%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
LK +R LG G FG+V + + VA+K+L+ G + QE ++ H
Sbjct 2209 LKLLRFLGSGAFGEVYEGQLKTEDSEEPQRVAIKSLRK--GASEFAELLQEAQLMSNFKH 2266
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------------PRHSIGLAQLLLFA 1004
E+I+ G C D +S+ L+ME++ G L YL P + L++LL
Sbjct 2267 ENIVCLVGICFDT--ESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMC 2324
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLL-------DNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ G +YL H++HRDLA RN L+ D R VKIGDFGLA+ + + +YYR
Sbjct 2325 IDVANGCSYLEDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKS-DYYRK 2383
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
+G PV W +PE L + F SDVW+FGV +E+LT + F L + +G
Sbjct 2384 EGEGLLPVRWMSPESLVDGLFTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEG 2443
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
RL +P C ++Y L+ CW T+ RP+F L +
Sbjct 2444 G--------------RLQQPPMCTEKLYSLLLLCWRTDPWERPSFRRCYNTLHAI 2484
Score = 84.7 bits (208), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 86/340 (25%), Positives = 143/340 (42%), Gaps = 49/340 (14%)
Query 557 ETSNLIIMRGARASPRTLNLSQLSF-HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615
+T ++ RA TL+ + ++ +++ ++ L LG G VYEG+L+ E S +
Sbjct 2176 QTQQQLMAVRNRAFSTTLSDADIALLPQINWSQLKLLRFLGSGAFGEVYEGQLKTEDSEE 2235
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675
P+ RV +K L + A E A LMS H ++ + G
Sbjct 2236 PQ--------------------RVAIKSLRKGASEFAELLQE-AQLMSNFKHENIVCLVG 2274
Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRERGH----------VPMAWKMVVAQQLASALSYL 725
+C ++ E++E G L +LR R + ++ + + +A+ SYL
Sbjct 2275 ICFDTESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMCIDVANGCSYL 2334
Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WL 779
E+ + VH ++ RN L+ + +K+ D G+ R+E +P W+
Sbjct 2335 EDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDYYRKEGEGLLPVRWM 2394
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--S 837
+PE L G +T D W FG EI G+ P +R+ E + RL +P
Sbjct 2395 SPESLVDGL--FTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEGGRLQQPPMC 2452
Query 838 CPQLATLTSQCLTYEPTQRPSFR-------TILRDLTRLQ 870
+L +L C +P +RPSFR I DL R Q
Sbjct 2453 TEKLYSLLLLCWRTDPWERPSFRRCYNTLHAISTDLRRTQ 2492
>sp|Q25197|HTK7_HYDVU Putative insulin-like peptide receptor OS=Hydra
vulgaris OX=6087 GN=HTK7 PE=2 SV=1
Length=1477
Score = 136 bits (343), Expect = 4e-31, Method: Compositional matrix adjust.
Identities = 100/312 (32%), Positives = 153/312 (49%), Gaps = 42/312 (13%)
Query 879 TVNPDSPAS------DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE----MVA 928
+VNP+ S D ++ ++ IR+LG+G FG V ++ G G+ VA
Sbjct 1020 SVNPEYMNSKEVYIPDEWELNREKIELIRELGQGSFGMV----FEGIAHGIGDHAELRVA 1075
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
VK + R QE I++ H++K G QG+ + +VME + G L+
Sbjct 1076 VKTTNENASIHDRIQILQEASIMKAFNCNHVVKLIGVVS-QGQPTF-VVMELMGRGDLKS 1133
Query 989 YLPRHS-------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
YL + ++ +I +GMAYL A+ ++H DLAARN ++ +D VKIGD
Sbjct 1134 YLKERRPDDGGIPLMRQEIYQMVAEIADGMAYLAARKFVHCDLAARNCMVASDFTVKIGD 1193
Query 1042 FGLAKAVPEGHEYYRVREDGDS--PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
FG+A+ + E + Y R+DG S P+ W APE LK+ F ASDVWSFGV L+E+ C
Sbjct 1194 FGMARDIYERNYY---RKDGKSLLPIRWMAPESLKDGIFSTASDVWSFGVVLWEI---CT 1247
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+ P QG+ L +L G L P+ C ++ M CW + R
Sbjct 1248 LASQP----------YQGKTNEQVLNFVLSNG-HLDYPEGCDYQLREFMSLCWHRDPKMR 1296
Query 1160 PTFENLIPILKT 1171
P+F ++ +L+
Sbjct 1297 PSFLEIVHVLEN 1308
Score = 90.5 bits (223), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 86/319 (27%), Positives = 137/319 (43%), Gaps = 50/319 (16%)
Query 567 ARASPRTLNLSQLSF---HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
A +P +N ++ +++++I + LGQG+ V+EG G GD
Sbjct 1019 ASVNPEYMNSKEVYIPDEWELNREKIELIRELGQGSFGMVFEGI--AHGIGDH------- 1069
Query 624 EDPLVPGRDRGQELRVVLKVLD--PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
ELRV +K + S HD + + AS+M + H+ + GV +G
Sbjct 1070 -----------AELRVAVKTTNENASIHD-RIQILQEASIMKAFNCNHVVKLIGVVSQGQ 1117
Query 682 ENIMVTEYVEHGPLDVWLRRER---GHVPMAWKMV--VAQQLASALSYLENKNLVHGNVC 736
+V E + G L +L+ R G +P+ + + + ++A ++YL + VH ++
Sbjct 1118 PTFVVMELMGRGDLKSYLKERRPDDGGIPLMRQEIYQMVAEIADGMAYLAARKFVHCDLA 1177
Query 737 GRNILLARLGLAEGTSPF-IKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGAN 789
RN ++A S F +K+ D G+ R + + I W+APE L G
Sbjct 1178 ARNCMVA--------SDFTVKIGDFGMARDIYERNYYRKDGKSLLPIRWMAPESLKDGI- 1228
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847
STA D W FG L EIC P Q ++ + +F L PE QL S
Sbjct 1229 -FSTASDVWSFGVVLWEICTLASQPYQGKTNEQVLNFVLSNGHLDYPEGCDYQLREFMSL 1287
Query 848 CLTYEPTQRPSFRTILRDL 866
C +P RPSF I+ L
Sbjct 1288 CWHRDPKMRPSFLEIVHVL 1306
>sp|Q78DX7|ROS1_MOUSE Proto-oncogene tyrosine-protein kinase ROS
OS=Mus musculus OX=10090 GN=Ros1 PE=1 SV=1
Length=2340
Score = 137 bits (344), Expect = 5e-31, Method: Compositional matrix adjust.
Identities = 95/258 (37%), Positives = 135/258 (52%), Gaps = 31/258 (12%)
Query 922 GTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
G+GE+ VAVK LK Q + + +E ++ H +I+K G C GE +++E
Sbjct 1964 GSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCL-LGEPQY-IILEL 2021
Query 981 VPLGSLRDYLPRH--------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032
+ G L YL + S+ L L+ I +G YL H+IHRDLAARN L+
Sbjct 2022 MEGGDLLSYLRKARGTTFHGPSLTLLDLVELCVDISKGCVYLEQMHFIHRDLAARNCLVS 2081
Query 1033 -----NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
+ R+VKIGDFGLA+ + + ++YYR R +G PV W APE L + F SDVWSF
Sbjct 2082 VKDYTSPRVVKIGDFGLAREIYK-NDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDVWSF 2140
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
G+ ++E+LT Q P A + VL ++ G RL P CP ++++L
Sbjct 2141 GILVWEILTL--GHQPYP---------AHSNLDVLN---YVQAGGRLEPPRNCPDDLWNL 2186
Query 1148 MKNCWETEASFRPTFENL 1165
M CW E RPTF N+
Sbjct 2187 MSQCWAQEPDQRPTFHNI 2204
Score = 90.1 bits (222), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 75/258 (29%), Positives = 121/258 (47%), Gaps = 21/258 (8%)
Query 636 ELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
E++V +K L D + F + A LMS+ +H ++ GVC+ G ++ E +E G
Sbjct 1967 EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLGEPQYIILELMEGGD 2026
Query 695 LDVWLRRERG---HVPMAWKMVVAQ---QLASALSYLENKNLVHGNVCGRNILLARLGLA 748
L +LR+ RG H P + + + ++ YLE + +H ++ RN L++ +
Sbjct 2027 LLSYLRKARGTTFHGPSLTLLDLVELCVDISKGCVYLEQMHFIHRDLAARNCLVS---VK 2083
Query 749 EGTSP-FIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFG 801
+ TSP +K+ D G+ + +R + W+APE L G ++ D W FG
Sbjct 2084 DYTSPRVVKIGDFGLAREIYKNDYYRKRGEGLLPVRWMAPENLMDGI--FTSQSDVWSFG 2141
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
+ EI G P + S + ++ Q RL P +CP L L SQC EP QRP+F
Sbjct 2142 ILVWEILTLGHQPYPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTF 2201
Query 860 RTILRDLTRLQPHNLADV 877
I L + L +V
Sbjct 2202 HNIQNQLQLFRNVFLNNV 2219
>sp|P09760|FER_RAT Tyrosine-protein kinase Fer OS=Rattus norvegicus
OX=10116 GN=Fer PE=1 SV=2
Length=823
Score = 135 bits (340), Expect = 5e-31, Method: Compositional matrix adjust.
Identities = 92/277 (33%), Positives = 139/277 (50%), Gaps = 29/277 (10%)
Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG+G+FG+V Y T D T VAVK K D + + + QE IL+ H +I+K
Sbjct 570 LGKGNFGEV----YKGTLKDKTP--VAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVK 623
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHY 1019
G C + + + ++ME VP G +L + + L QL+ F+ + GM YL ++
Sbjct 624 LIGVCTQR--QPVYIIMELVPGGDFLSFLRKRKDELKLKQLVRFSLDVAAGMLYLEGKNC 681
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRDLAARN L+ + +KI DFG+++ G Y P+ W APE L ++
Sbjct 682 IHRDLAARNCLVGENNTLKISDFGMSRQEDGG--VYSSSGLKQIPIKWTAPEALNYGRYS 739
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA-QGQMTVLRLTELLERGERLPRPD 1138
SDVWSFG+ L+E + +G+ MT + E +ERG R+ P
Sbjct 740 SESDVWSFGILLWETFS---------------LGVCPYPGMTNQQAREQVERGYRMSAPQ 784
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
CP E++ +M CW+ + RP F +L L + +K
Sbjct 785 NCPEEIFTIMMKCWDYKPENRPKFSDLHKELTAIKKK 821
Score = 87.8 bits (216), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 101/434 (23%), Positives = 182/434 (42%), Gaps = 86/434 (20%)
Query 449 DGIHGPLLEPFVQAK-LRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPI 507
D HG + P ++A+ L + G +L+ S P +L+V DG + R F I
Sbjct 460 DWYHGAI--PRIEAQELLKQQGDFLVRESHGKPGEYVLSVY-----SDGQR----RHFII 508
Query 508 EQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGA 567
+ D + EG G F ++ +L D F+ ++ + G ++++
Sbjct 509 QFVDNLYRFEGTG--FSNIPQLI-----------DHHFNTKQVITKKSG----VVLLNPI 551
Query 568 RASPR-TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+ LN +S + LG+G VY+G L+ D+ P
Sbjct 552 PKDKKWVLNHEDVSLGEL----------LGKGNFGEVYKGTLK-------------DKTP 588
Query 627 LVPG---RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
+ D QEL++ F + A ++ Q H ++ + GVC +
Sbjct 589 VAVKTCKEDLPQELKI--------------KFLQEAKILKQYDHPNIVKLIGVCTQRQPV 634
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
++ E V G +LR+ + + + + + +A+ + YLE KN +H ++ RN L+
Sbjct 635 YIIMELVPGGDFLSFLRKRKDELKLKQLVRFSLDVAAGMLYLEGKNCIHRDLAARNCLV- 693
Query 744 RLGLAEGTSPFIKLSDPGVGL---GALSREERVERIP--WLAPECLPGGANSLSTAMDKW 798
G + +K+SD G+ G + +++IP W APE L G S+ D W
Sbjct 694 ------GENNTLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYG--RYSSESDVW 745
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQR 856
FG L E G P + + +R +R+ P +CP ++ T+ +C Y+P R
Sbjct 746 SFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQNCPEEIFTIMMKCWDYKPENR 805
Query 857 PSFRTILRDLTRLQ 870
P F + ++LT ++
Sbjct 806 PKFSDLHKELTAIK 819
>sp|P20806|7LESS_DROVI Protein sevenless OS=Drosophila virilis
OX=7244 GN=sev PE=3 SV=1
Length=2594
Score = 137 bits (344), Expect = 5e-31, Method: Compositional matrix adjust.
Identities = 90/291 (31%), Positives = 141/291 (48%), Gaps = 34/291 (12%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L +R LG G FG+V ++ + VA+K+L+ G + QE ++ H
Sbjct 2224 LTLLRFLGSGAFGEVYEGQLQAEDEAQPQRVAIKSLRK--GASEFAELLQEAQLMSNFKH 2281
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---------PRHSIGLAQLLLFAQQI 1007
E+I+ G C D S+ L+ME++ G L YL + L +LL +
Sbjct 2282 ENIVCLIGICCD--TDSISLIMEHMEAGDLLSYLRAARPSSQEALSKLQLPELLSMCLDV 2339
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDND------RLVKIGDFGLAKAVPEGHEYYRVREDG 1061
G +Y+ H++HRDLA RN L+ + R+VKIGDFGLA+ + + +YYR +G
Sbjct 2340 ANGCSYMEDMHFVHRDLACRNCLVSDGAAIGGRRIVKIGDFGLARDIYKS-DYYRKEGEG 2398
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
PV W A E L + F SDVW+FGV +E+ T + F L + +G
Sbjct 2399 LLPVRWMALESLVDGLFSTQSDVWAFGVLCWEIFTLGQQPYAARNNFEVLAHVKEGG--- 2455
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
RL +P++CP ++Y L+ CW +E RP+F+ + L+ +
Sbjct 2456 -----------RLQQPERCPEKLYALLLQCWRSEPWERPSFKRCLSTLQAL 2495
Score = 91.3 bits (225), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 88/324 (27%), Positives = 139/324 (43%), Gaps = 42/324 (13%)
Query 564 MRGARASPRTLNLSQLSFH---RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620
+ AR+ +++LS +++ +T L LG G VYEG+L+ E P+
Sbjct 2196 LLAARSRTFSMSLSDADIALLPQINWNRLTLLRFLGSGAFGEVYEGQLQAEDEAQPQ--- 2252
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680
RV +K L + A + A LMS H ++ + G+C
Sbjct 2253 -----------------RVAIKSLRKGASEFA-ELLQEAQLMSNFKHENIVCLIGICCDT 2294
Query 681 PENIMVTEYVEHGPLDVWLRRER-------GHVPMAWKMVVAQQLASALSYLENKNLVHG 733
++ E++E G L +LR R + + + + +A+ SY+E+ + VH
Sbjct 2295 DSISLIMEHMEAGDLLSYLRAARPSSQEALSKLQLPELLSMCLDVANGCSYMEDMHFVHR 2354
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGG 787
++ RN L++ G A G +K+ D G+ R+E +P W+A E L G
Sbjct 2355 DLACRNCLVSD-GAAIGGRRIVKIGDFGLARDIYKSDYYRKEGEGLLPVRWMALESLVDG 2413
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLT 845
ST D W FG EI G+ P +R+ E + RL +P CP+ L L
Sbjct 2414 L--FSTQSDVWAFGVLCWEIFTLGQQPYAARNNFEVLAHVKEGGRLQQPERCPEKLYALL 2471
Query 846 SQCLTYEPTQRPSFRTILRDLTRL 869
QC EP +RPSF+ L L L
Sbjct 2472 LQCWRSEPWERPSFKRCLSTLQAL 2495
>sp|Q9WTL4|INSRR_MOUSE Insulin receptor-related protein OS=Mus
musculus OX=10090 GN=Insrr PE=1 SV=2
Length=1300
Score = 135 bits (341), Expect = 7e-31, Method: Compositional matrix adjust.
Identities = 94/283 (33%), Positives = 147/283 (52%), Gaps = 37/283 (13%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDG--TGEM---VAVKALKADCGPQHRSGWKQEIDILRTL 954
IR+LG+G FG V Y+ G GE VA+K + + R + +E +++
Sbjct 982 IRELGQGSFGMV----YEGLARGLEAGEESTPVALKTVNELASARERVEFLKEASVMKAF 1037
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQ-----LLLF 1003
H+++ G QG+ +L ++ME + G L+ +L ++ GL Q ++
Sbjct 1038 KCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSHLRSLRPEAENNPGLPQPALSDMIQM 1095
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
A +I +GMAYL A+ ++HRDLAARN ++ D VKIGDFG+ + V E +YYR G
Sbjct 1096 AGEIADGMAYLAAKKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYE-TDYYRKGGKGLL 1154
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
PV W APE LK+ F SDVWSFGV L+E++T + G++ Q+
Sbjct 1155 PVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQ---------GLSNEQV---- 1201
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ + G L + CP ++ LM+ CW+ RPTF +++
Sbjct 1202 -LKFVMDGGVLEELENCPIQLQELMRLCWQHSPRLRPTFVHIL 1243
Score = 73.6 bits (179), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 76/298 (26%), Positives = 121/298 (41%), Gaps = 46/298 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLR-VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
V +++I + LGQG+ VYEG R +E + + + L R+R
Sbjct 974 VPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASARER--------- 1024
Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+ F + AS+M H+ + GV +G +++ E + G L LR
Sbjct 1025 ----------VEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSL 1074
Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
R P M+ +A ++A ++YL K VH ++ RN ++++
Sbjct 1075 RPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQ-------DF 1127
Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+ D G+ + + + + W+APE L G +T D W FG L EI
Sbjct 1128 TVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGI--FTTHSDVWSFGVVLWEI 1185
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSFRTIL 863
E P Q S + F L E +CP QL L C + P RP+F IL
Sbjct 1186 VTLAEQPYQGLSNEQVLKFVMDGGVLEELENCPIQLQELMRLCWQHSPRLRPTFVHIL 1243
>sp|P70451|FER_MOUSE Tyrosine-protein kinase Fer OS=Mus musculus
OX=10090 GN=Fer PE=1 SV=2
Length=823
Score = 135 bits (339), Expect = 7e-31, Method: Compositional matrix adjust.
Identities = 90/267 (34%), Positives = 136/267 (51%), Gaps = 29/267 (11%)
Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG+G+FG+V Y T D T VA+K K D + + + QE IL+ H +I+K
Sbjct 570 LGKGNFGEV----YKGTLKDKTP--VAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVK 623
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHY 1019
G C + + + ++ME VP G +L + + L QL+ F+ + GM YL +++
Sbjct 624 LIGVCTQR--QPVYIIMELVPGGDFLTFLRKRKDELKLKQLVRFSLDVAAGMLYLESKNC 681
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRDLAARN L+ + +KI DFG+++ G Y P+ W APE L ++
Sbjct 682 IHRDLAARNCLVGENNTLKISDFGMSRQEDGG--VYSSSGLKQIPIKWTAPEALNYGRYS 739
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA-QGQMTVLRLTELLERGERLPRPD 1138
SDVWSFG+ L+E + +G+ MT + E +ERG R+ P
Sbjct 740 SESDVWSFGILLWETFS---------------LGVCPYPGMTNQQAREQVERGYRMSAPQ 784
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENL 1165
CP EV+ +M CW+ + RP F +L
Sbjct 785 NCPEEVFTIMMKCWDYKPENRPKFNDL 811
Score = 90.5 bits (223), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 104/453 (23%), Positives = 191/453 (42%), Gaps = 86/453 (19%)
Query 430 SSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAK-LRPEDGLYLIHWSTSHPYRLILTVA 488
SS +C ++ ++ D HG + P ++A+ L + G +L+ S P +L+V
Sbjct 441 SSTQVCDVISVGERPLAEHDWYHGAI--PRIEAQELLKQQGDFLVRESHGKPGEYVLSVY 498
Query 489 QRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLR 548
DG + R F I+ D + EG G F ++ +L D F+ +
Sbjct 499 -----SDGQR----RHFIIQFVDNLYRFEGTG--FSNIPQLI-----------DHHFNTK 536
Query 549 RCCLPQPGETSNLIIMRGARASPR-TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
+ + G ++++ + LN +S + LG+G VY+G
Sbjct 537 QVITKKSG----VVLLNPIPKDKKWVLNHEDVSLGEL----------LGKGNFGEVYKGT 582
Query 608 LRVEGSGDPEEGKMDDEDPLVPG---RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664
L+ D+ P+ D QEL++ F + A ++ Q
Sbjct 583 LK-------------DKTPVAIKTCKEDLPQELKI--------------KFLQEAKILKQ 615
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
H ++ + GVC + ++ E V G +LR+ + + + + + +A+ + Y
Sbjct 616 YDHPNIVKLIGVCTQRQPVYIIMELVPGGDFLTFLRKRKDELKLKQLVRFSLDVAAGMLY 675
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---GALSREERVERIP--WL 779
LE+KN +H ++ RN L+ G + +K+SD G+ G + +++IP W
Sbjct 676 LESKNCIHRDLAARNCLV-------GENNTLKISDFGMSRQEDGGVYSSSGLKQIPIKWT 728
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838
APE L G S+ D W FG L E G P + + +R +R+ P +C
Sbjct 729 APEALNYG--RYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQNC 786
Query 839 P-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P ++ T+ +C Y+P RP F + ++LT ++
Sbjct 787 PEEVFTIMMKCWDYKPENRPKFNDLHKELTVIK 819
>sp|P09208|INSR_DROME Insulin-like receptor OS=Drosophila melanogaster
OX=7227 GN=InR PE=1 SV=3
Length=2144
Score = 136 bits (342), Expect = 7e-31, Method: Compositional matrix adjust.
Identities = 95/294 (32%), Positives = 152/294 (52%), Gaps = 45/294 (15%)
Query 903 LGEGHFGKVS---LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG V L + P +G A+K + + + R+ + E +++ H+
Sbjct 1377 LGQGSFGMVYEGILKSFPP--NGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHV 1434
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------------IGLA------- 998
++ G C +G+ +L +VME + G L+ YL H IG+
Sbjct 1435 VRLLGVCS-RGQPAL-VVMELMKKGDLKSYLRAHRPEERDEAMMTYLNRIGVTGNVQPPT 1492
Query 999 --QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
++ A +I +GMAYL A+ ++HRDLAARN ++ +D VKIGDFG+ + + E +YYR
Sbjct 1493 YGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYET-DYYR 1551
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
G PV W PE L++ + ASDV+SFGV L+E+ T + P + G++
Sbjct 1552 KGTKGLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLA----AQPYQ-----GLSN 1602
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
Q VLR + G + RP+ CP ++ LM+ CW +S RP+F ++I L+
Sbjct 1603 EQ--VLR---YVIDGGVMERPENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLE 1651
Score = 66.2 bits (160), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 79/310 (25%), Positives = 128/310 (41%), Gaps = 58/310 (19%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V ++ I QL+ LGQG+ VYEG L+ S P G DR +K
Sbjct 1366 VLRENIIQLAPLGQGSFGMVYEGILK---SFPPN------------GVDR----ECAIKT 1406
Query 644 LDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
++ + D F AS+M + H+ + GVC RG ++V E ++ G L +LR
Sbjct 1407 VNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSYLRAH 1466
Query 703 R------------------GHV-PMAWKMV--VAQQLASALSYLENKNLVHGNVCGRNIL 741
R G+V P + + +A ++A ++YL K VH ++ RN +
Sbjct 1467 RPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCM 1526
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAM 795
+A +K+ D G+ + + + + W+ PE L G S+A
Sbjct 1527 VA-------DDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGV--YSSAS 1577
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEP 853
D + FG L E+ P Q S + + + P +CP L L +C +
Sbjct 1578 DVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCWHHRS 1637
Query 854 TQRPSFRTIL 863
+ RPSF I+
Sbjct 1638 SARPSFLDII 1647
>sp|G5EGK5|CAM1_CAEEL Tyrosine-protein kinase receptor cam-1 OS=Caenorhabditis
elegans OX=6239 GN=cam-1 PE=1 SV=1
Length=928
Score = 135 bits (339), Expect = 9e-31, Method: Compositional matrix adjust.
Identities = 96/281 (34%), Positives = 134/281 (48%), Gaps = 29/281 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG FG V Y M VAVK + D R+ +QEI + T H ++IK
Sbjct 596 IGEGQFGVVHSGIYTSGLFAPEPMAVAVKKCRHDATNAERAQLEQEIRAVATFDHPNVIK 655
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIG-----LAQLLLFAQQICEG 1010
G C + SL V EY+ G L + L H +G A+ L A QI G
Sbjct 656 LIGVC--YMDNSLLAVFEYMVHGDLHELLKVRVPPADHDMGGITEANAEFLYIATQIALG 713
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
M YL + ++HRDLA RN L+ + R +KI DFGL + G +YY++ PV W +
Sbjct 714 MEYLASMSFVHRDLATRNCLVGDTRTIKIADFGLMR-TSYGSDYYKMLHRSWMPVRWMSK 772
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E +++ +F ASDVWSFGVTL+E+ + + P G + Q + EL+
Sbjct 773 EAIEQGRFSEASDVWSFGVTLWEIWSF---GRQP------YEGASNQQ-----VIELVAN 818
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
L P CP +Y LM CW RPTF + L++
Sbjct 819 RHLLECPHNCPTNIYSLMVECWHENIERRPTFSEIRSRLQS 859
Score = 60.5 bits (145), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 61/231 (26%), Positives = 103/231 (45%), Gaps = 29/231 (13%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-------RERGHVPMAWK--M 712
++ H ++ + GVC + V EY+ HG L L+ + G + A +
Sbjct 645 VATFDHPNVIKLIGVCYMDNSLLAVFEYMVHGDLHELLKVRVPPADHDMGGITEANAEFL 704
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
+A Q+A + YL + + VH ++ RN L+ G + IK++D G+ + +
Sbjct 705 YIATQIALGMEYLASMSFVHRDLATRNCLV-------GDTRTIKIADFGLMRTSYGSDYY 757
Query 771 ERVER----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ + R + W++ E + G S A D W FG TL EI G P + S +
Sbjct 758 KMLHRSWMPVRWMSKEAIEQG--RFSEASDVWSFGVTLWEIWSFGRQPYEGASNQQVIEL 815
Query 827 YQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+H L P +CP + +L +C +RP+F I +RLQ +LA
Sbjct 816 VANRHLLECPHNCPTNIYSLMVECWHENIERRPTFSEI---RSRLQSWSLA 863
>sp|P14616|INSRR_HUMAN Insulin receptor-related protein OS=Homo
sapiens OX=9606 GN=INSRR PE=1 SV=2
Length=1297
Score = 135 bits (340), Expect = 1e-30, Method: Compositional matrix adjust.
Identities = 102/321 (32%), Positives = 161/321 (50%), Gaps = 50/321 (16%)
Query 879 TVNPDS-PASDPTV-----FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG--TGEM---V 927
+VNP+ ASD V + + IR+LG+G FG V Y+ G GE V
Sbjct 955 SVNPEYFSASDMYVPDEWEVPREQISIIRELGQGSFGMV----YEGLARGLEAGEESTPV 1010
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K + P+ + +E +++ H+++ G QG+ +L ++ME + G L+
Sbjct 1011 ALKTVNELASPRECIEFLKEASVMKAFKCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLK 1068
Query 988 DYL-------------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034
+L P+ ++G +++ A +I +GMAYL A ++HRDLAARN ++ D
Sbjct 1069 SHLRSLRPEAENNPGLPQPALG--EMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQD 1126
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
VKIGDFG+ + V E +YYR G PV W APE LK+ F SDVWSFGV L+E+
Sbjct 1127 FTVKIGDFGMTRDVYE-TDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEI 1185
Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154
+T + G++ Q+ + + G L + CP ++ LM CW+
Sbjct 1186 VTLAEQPYQ---------GLSNEQV-----LKFVMDGGVLEELEGCPLQLQELMSRCWQP 1231
Query 1155 EASFRPTFENLIPILKTVHEK 1175
RP+F + IL ++ E+
Sbjct 1232 NPRLRPSFTH---ILDSIQEE 1249
Score = 75.9 bits (185), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 78/300 (26%), Positives = 126/300 (42%), Gaps = 44/300 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +++I+ + LGQG+ VYEG R +G+ + P+ L+ V ++
Sbjct 974 VPREQISIIRELGQGSFGMVYEGLARGLEAGE-------ESTPVA--------LKTVNEL 1018
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
P + F + AS+M H+ + GV +G +++ E + G L LR R
Sbjct 1019 ASPRE---CIEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLR 1075
Query 704 GHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
P +M+ +A ++A ++YL VH ++ RN ++++
Sbjct 1076 PEAENNPGLPQPALGEMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQ-------DFT 1128
Query 755 IKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+K+ D G+ + + + + W+APE L G +T D W FG L EI
Sbjct 1129 VKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGI--FTTHSDVWSFGVVLWEIV 1186
Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSFRTILRDL 866
E P Q S + F L E CP QL L S+C P RPSF IL +
Sbjct 1187 TLAEQPYQGLSNEQVLKFVMDGGVLEELEGCPLQLQELMSRCWQPNPRLRPSFTHILDSI 1246
>sp|Q05876|FYN_CHICK Tyrosine-protein kinase Fyn OS=Gallus gallus
OX=9031 GN=FYN PE=1 SV=2
Length=534
Score = 132 bits (331), Expect = 1e-30, Method: Compositional matrix adjust.
Identities = 88/273 (32%), Positives = 136/273 (50%), Gaps = 29/273 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+ LG+G F +V + T +G + VA+K LK G + +E I++ L H+ ++
Sbjct 272 QKLGQGCFAEV----WRGTWNGNTK-VAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLV 324
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ + + +V EY+ GSL +L ++ L L+ A Q+ GMAY+
Sbjct 325 QLYAVVS---RRPIYIVTEYMSKGSLLIFLKDGEGRALKLPNLVDMAAQVAAGMAYIERM 381
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+YIHRDL + N+L+ N + KI DFGLA+ + + Y R+ P+ W APE +
Sbjct 382 NYIHRDLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGR 439
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFG+ L EL+T + M + E +ERG R+P P
Sbjct 440 FTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYRMPCP 485
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
CP ++ LM +CW+ + RPTFE L L+
Sbjct 486 QDCPISLHELMIHCWKKDPEERPTFEYLQGFLE 518
Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 66/230 (29%), Positives = 104/230 (45%), Gaps = 19/230 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P +F E A +M ++ H L ++ V R P I VTEY+ G L +
Sbjct 292 KVAIKTLKPGTMSPE-SFLEEAQIMKKLKHDKLVQLYAVVSRRPIYI-VTEYMSKGSLLI 349
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G K
Sbjct 350 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GNGLICK 402
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 403 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 460
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
P + E +R +R+P P CP L L C +P +RP+F
Sbjct 461 RVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 510
>sp|Q10925|SID3_CAEEL Tyrosine-protein kinase sid-3 OS=Caenorhabditis
elegans OX=6239 GN=sid-3 PE=1 SV=2
Length=1237
Score = 134 bits (338), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 90/264 (34%), Positives = 133/264 (50%), Gaps = 24/264 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG F V + +N GT VAVK L+ D P + E L L H +I+
Sbjct 113 IGEGSFAVVKRGTWTQSN-GTHVNVAVKILR-DISPNIMDDLRVEASHLLKLQHPSLIRL 170
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
G + +V E GSL D L + + +++L + QI + + +L ++H
Sbjct 171 YGIVR----QPAMMVFELCEGGSLLDRLRDDKKAILLVSRLHDYCMQIAKALQFLESKHC 226
Query 1020 IHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRD+AARN+LL D R VKI DFGL +A+ E + Y + P W PE L+ KF
Sbjct 227 VHRDVAARNILLARDERTVKICDFGLMRALKENEQMYTMAPQKKVPFAWCPPEALRHRKF 286
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+ASDVWS+GVT++E+ T F E + + VL+ ++ GERL +P
Sbjct 287 SHASDVWSYGVTIWEVFT-----------FGEEPWVGCRAIDVLK---NIDAGERLEKPK 332
Query 1139 KCPCEVYHLMKNCWETEASFRPTF 1162
C +Y +MKNCW+ + R F
Sbjct 333 YCSERIYQIMKNCWKFNPAERCKF 356
Score = 67.0 bits (162), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 72/247 (29%), Positives = 114/247 (46%), Gaps = 22/247 (9%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
+ G + V +K+L +I AS + ++ H L ++G+ VR P +MV E
Sbjct 128 QSNGTHVNVAVKILRDISPNIMDDLRVEASHLLKLQHPSLIRLYGI-VRQPA-MMVFELC 185
Query 691 EHGPLDVWLRRERGHVPMAWKM-VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
E G L LR ++ + + ++ Q+A AL +LE+K+ VH +V RNILLAR E
Sbjct 186 EGGSLLDRLRDDKKAILLVSRLHDYCMQIAKALQFLESKHCVHRDVAARNILLAR---DE 242
Query 750 GTSPFIKLSDPGVGLGALSREERV------ERIP--WLAPECLPGGANSLSTAMDKWGFG 801
T +K+ D G+ + AL E++ +++P W PE L S A D W +G
Sbjct 243 RT---VKICDFGL-MRALKENEQMYTMAPQKKVPFAWCPPEAL--RHRKFSHASDVWSYG 296
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSF 859
T+ E+ GE P + RL +P C + + + C + P +R F
Sbjct 297 VTIWEVFTFGEEPWVGCRAIDVLKNIDAGERLEKPKYCSERIYQIMKNCWKFNPAERCKF 356
Query 860 RTILRDL 866
I DL
Sbjct 357 GAIREDL 363
>sp|P42681|TXK_HUMAN Tyrosine-protein kinase TXK OS=Homo sapiens
OX=9606 GN=TXK PE=1 SV=3
Length=527
Score = 131 bits (329), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 91/289 (31%), Positives = 137/289 (47%), Gaps = 47/289 (16%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGE-----MVAVKALKADCGPQHRSGWKQEIDILRTL 954
I+++G G FG V L GE VA+KA+ G + +E ++ L
Sbjct 274 IKEIGSGQFGVVHL----------GEWRSHIQVAIKAINE--GSMSEEDFIEEAKVMMKL 321
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMA 1012
H +++ G C + K L +V E++ G L +YL + L + +L + Q ICEGM
Sbjct 322 SHSKLVQLYGVCIQR--KPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGME 379
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
YL YIHRDLAARN L+ + +VKI DFG+ + V + Y P+ W PE
Sbjct 380 YLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDE--YVSSFGAKFPIKWSPPEV 437
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM-----TVLRLTEL 1127
K+ SDVWSFGV ++E+ T +G+M + L++ E
Sbjct 438 FLFNKYSSKSDVWSFGVLMWEVFT-------------------EGKMPFENKSNLQVVEA 478
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
+ G RL RP P +Y +M +CW + RPTF L+ + + E +
Sbjct 479 ISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW 527
Score = 89.0 bits (219), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 60/223 (27%), Positives = 106/223 (48%), Gaps = 18/223 (8%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F E A +M ++SH+ L ++GVC++ +VTE++E+G L +LR +G + + V
Sbjct 311 FIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSV 370
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
Q + + YLE +H ++ RN L++ ++ +K+SD G+ L +E V
Sbjct 371 CQDICEGMEYLERNGYIHRDLAARNCLVS-------STCIVKISDFGMTRYVLD-DEYVS 422
Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
I W PE N S+ D W FG + E+ +G+ P +++S +
Sbjct 423 SFGAKFPIKWSPPEVFL--FNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAIS 480
Query 829 RQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869
RL P ++ + C +P RP+F +LR +T +
Sbjct 481 EGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEI 523
>sp|P00530|FPS_FUJSV Tyrosine-protein kinase transforming protein
Fps OS=Fujinami sarcoma virus OX=11885 GN=V-FPS PE=3 SV=1
Length=873
Score = 134 bits (336), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 90/276 (33%), Positives = 140/276 (51%), Gaps = 31/276 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G+FG+V + D T VAVK+ + P+ ++ + QE IL+ H +I++
Sbjct 618 IGRGNFGEV--FSGRLRADNTP--VAVKSCRETLPPELKAKFLQEARILKQCNHPNIVRL 673
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
G C + + + +VME V G +L PR + + +L+ + GM YL ++H
Sbjct 674 IGVCTQK--QPIYIVMELVQGGDFLSFLRSKGPR--LKMKKLIKMMENAAAGMEYLESKH 729
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRDLAARN L+ +KI DFG+++ +G Y PV W APE L +
Sbjct 730 CIHRDLAARNCLVTEKNTLKISDFGMSRQEEDG-VYASTGGMKQIPVKWTAPEALNYGWY 788
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SDVWSFG+ L+E + L + ++ + E +E+G RL P+
Sbjct 789 SSESDVWSFGILLWEAFS--------------LGAVPYANLSNQQTREAIEQGVRLEPPE 834
Query 1139 KCPCEVYHLMKNCWETEASFRPTF----ENLIPILK 1170
+CP +VY LM+ CWE + RP+F ++LI I K
Sbjct 835 QCPEDVYRLMQRCWEYDPHRRPSFGAVHQDLIAIRK 870
Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 72/280 (26%), Positives = 124/280 (44%), Gaps = 40/280 (14%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
+G+G V+ GRLR D P+ ++ + L P ++
Sbjct 618 IGRGNFGEVFSGRLRA------------DNTPVA--------VKSCRETLPP---ELKAK 654
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F + A ++ Q +H ++ + GVC + +V E V+ G +LR + + M + +
Sbjct 655 FLQEARILKQCNHPNIVRLIGVCTQKQPIYIVMELVQGGDFLSFLRSKGPRLKMKKLIKM 714
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSRE 770
+ A+ + YLE+K+ +H ++ RN L+ +K+SD G+ G +
Sbjct 715 MENAAAGMEYLESKHCIHRDLAARNCLVTEKNT-------LKISDFGMSRQEEDGVYAST 767
Query 771 ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
+++IP W APE L G S+ D W FG L E G P + S + +
Sbjct 768 GGMKQIPVKWTAPEALNYGW--YSSESDVWSFGILLWEAFSLGAVPYANLSNQQTREAIE 825
Query 829 RQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866
+ RL P CP+ + L +C Y+P +RPSF + +DL
Sbjct 826 QGVRLEPPEQCPEDVYRLMQRCWEYDPHRRPSFGAVHQDL 865
>sp|Q6P6U0|FGR_RAT Tyrosine-protein kinase Fgr OS=Rattus norvegicus
OX=10116 GN=Fgr PE=1 SV=1
Length=517
Score = 130 bits (328), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 91/288 (32%), Positives = 137/288 (48%), Gaps = 29/288 (10%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
A D + + R LG G FG V L ++ + VAVK LK G +
Sbjct 240 AKDAWEIDRNSIALDRRLGTGCFGDVWLGTWNCSTK-----VAVKTLKP--GTMSPKAFL 292
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLL 1002
+E I++ L H+ +++ E+ + +V E++ GSL D+L H++ L L+
Sbjct 293 EEAQIMKLLRHDKLVQLYAVV---SEEPIYIVTEFMCYGSLLDFLKDRKGHNLMLPNLVD 349
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
A Q+ EGMAY+ +YIHRDL A N+L+ + KI DFGLA+ + + Y ++
Sbjct 350 MAAQVAEGMAYMERMNYIHRDLRAANILVGEHLICKIADFGLARLIVDDE--YNPQQGTK 407
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
P+ W APE +F SDVWSFG+ L EL+T + M
Sbjct 408 FPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGR--------------VPYPGMNNR 453
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ E +E G +P P CP +Y +M+ W + RPTFE L L+
Sbjct 454 EVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLE 501
Score = 75.1 bits (183), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 64/233 (27%), Positives = 105/233 (45%), Gaps = 19/233 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P AF E A +M + H L ++ V P I VTE++ +G L
Sbjct 275 KVAVKTLKPGTMS-PKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYI-VTEFMCYGSLLD 332
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ +GH M +V +A Q+A ++Y+E N +H ++ NIL+ G K
Sbjct 333 FLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILV-------GEHLICK 385
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ + E ++ I W APE G ++ + D W FG L E+ G
Sbjct 386 IADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKS--DVWSFGILLTELITKG 443
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTI 862
P + E + + +P P CP L + Q +P +RP+F +
Sbjct 444 RVPYPGMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYL 496
>sp|P00542|FES_FSVGA Tyrosine-protein kinase transforming protein
Fes OS=Feline sarcoma virus (strain Gardner-Arnstein) OX=11774
GN=V-FES PE=3 SV=1
Length=609
Score = 132 bits (331), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 93/310 (30%), Positives = 149/310 (48%), Gaps = 24/310 (8%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
QP + +N P D V + L +G G+FG+V + D T +VAV
Sbjct 322 QPLTKKSGIVLNRAVP-KDKWVLNHEDLVLGEQIGRGNFGEV--FSGRLRADNT--LVAV 376
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K+ + P ++ + QE IL+ H +I++ G C + + + +VME V G +
Sbjct 377 KSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVCTQK--QPIYIVMELVQGGDFLTF 434
Query 990 LPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
L + + LL GM YL ++ IHRDLAARN L+ ++KI DFG+++
Sbjct 435 LRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSRE 494
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+G Y PV W APE L ++ SDVWSFG+ L+E + +S P
Sbjct 495 AADGI-YAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFS-LGASPYP--- 549
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
++ + E +E+G RLP P+ CP V+ LM+ CW E RP+F +
Sbjct 550 ----------NLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQ 599
Query 1168 ILKTVHEKYQ 1177
L+++ ++++
Sbjct 600 ELQSIRKRHR 609
Score = 100 bits (249), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 82/285 (29%), Positives = 127/285 (45%), Gaps = 40/285 (14%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
+G+G V+ GRLR + + LV ++ + L P DI
Sbjct 353 QIGRGNFGEVFSGRLRADNT-------------LVA-------VKSCRETLPP---DIKA 389
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F + A ++ Q SH ++ + GVC + +V E V+ G +LR E + M +
Sbjct 390 KFLQEAKILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQ 449
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGAL 767
+ A+ + YLE+K +H ++ RN L+ + +K+SD G+ G+ A
Sbjct 450 MVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNV-------LKISDFGMSREAADGIYAA 502
Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
S R + W APE L G S+ D W FG L E G +P + S + F
Sbjct 503 SGGLRQVPVKWTAPEALNYG--RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFV 560
Query 828 QRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
++ RLP P CP + L QC YEP QRPSF I ++L ++
Sbjct 561 EKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQELQSIR 605
>sp|Q968Y9|INSR_CAEEL Insulin-like receptor OS=Caenorhabditis
elegans OX=6239 GN=daf-2 PE=1 SV=2
Length=1846
Score = 134 bits (337), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 99/292 (34%), Positives = 137/292 (47%), Gaps = 50/292 (17%)
Query 904 GEGHFGKVSLYCYDPTNDGTGEMV-----------AVKALKADCGPQHRSGWKQEIDILR 952
GEG FGKV L GTG V A+K D + E +I++
Sbjct 1253 GEGSFGKVYL--------GTGNNVVSLMGDRFGPCAIKINVDDPASTENLNYLMEANIMK 1304
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------------IGL 997
I+K G + +VME + LG+LRDYL I
Sbjct 1305 NFKTNFIVKLYGVISTV--QPAMVVMEMMDLGNLRDYLRSKREDEVFNETDCNFFDIIPR 1362
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ +A QIC+GMAYL + + HRDLAARN +++ D VKIGDFG+A+ + H+YY+
Sbjct 1363 DKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFY-HDYYKP 1421
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
PV W +PE LK+ KF SDVWSFGV LYE++T P IG++
Sbjct 1422 SGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTL---GAQP------YIGLSND 1472
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ VL + + + +P+ C Y +MK CW RPTF L+ +L
Sbjct 1473 E--VLNYIGMARK--VIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLVHLL 1520
Score = 57.4 bits (137), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 54/250 (22%), Positives = 98/250 (39%), Gaps = 32/250 (13%)
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
DR + + V DP+ + L + A++M + ++GV ++V E ++
Sbjct 1274 DRFGPCAIKINVDDPASTE-NLNYLMEANIMKNFKTNFIVKLYGVISTVQPAMVVMEMMD 1332
Query 692 HGPLDVWLRRERGH-------------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGR 738
G L +LR +R +P A Q+ ++YLE+ H ++ R
Sbjct 1333 LGNLRDYLRSKREDEVFNETDCNFFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAAR 1392
Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLS 792
N ++ R +K+ D G+ + +R+ + W++PE L G
Sbjct 1393 NCMINR-------DETVKIGDFGMARDLFYHDYYKPSGKRMMPVRWMSPESLKDG--KFD 1443
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-LPEPSCPQ--LATLTSQCL 849
+ D W FG L E+ G P S E ++ + + +P C + + C
Sbjct 1444 SKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCW 1503
Query 850 TYEPTQRPSF 859
Y P RP+F
Sbjct 1504 RYSPRDRPTF 1513
>sp|P35991|BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus musculus
OX=10090 GN=Btk PE=1 SV=4
Length=659
Score = 132 bits (331), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 87/279 (31%), Positives = 139/279 (50%), Gaps = 28/279 (10%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+++LG G FG V + D VA+K ++ G + +E ++ L HE +
Sbjct 405 LKELGTGQFGVVKYGKWRGQYD-----VAIKMIRE--GSMSEDEFIEEAKVMMNLSHEKL 457
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ 1017
++ G C Q + + ++ EY+ G L +YL RH QLL + +CE M YL ++
Sbjct 458 VQLYGVCTKQ--RPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESK 515
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
++HRDLAARN L+++ +VK+ DFGL++ V + Y PV W PE L K
Sbjct 516 QFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDE--YTSSVGSKFPVRWSPPEVLMYSK 573
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SD+W+FGV ++E+ + L + + T E + +G RL RP
Sbjct 574 FSSKSDIWAFGVLMWEIYS--------------LGKMPYERFTNSETAEHIAQGLRLYRP 619
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP-ILKTVHEK 1175
VY +M +CW +A RP+F+ L+ IL + E+
Sbjct 620 HLASERVYTIMYSCWHEKADERPSFKILLSNILDVMDEE 658
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 82/317 (26%), Positives = 136/317 (43%), Gaps = 55/317 (17%)
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP-----E 617
+ + + +P T L S+ +D K++T L LG G V G+ R G D
Sbjct 377 VSKQNKNAPSTAGLGYGSWE-IDPKDLTFLKELGTGQFGVVKYGKWR--GQYDVAIKMIR 433
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
EG M +++ F E A +M +SH L ++GVC
Sbjct 434 EGSMSEDE-----------------------------FIEEAKVMMNLSHEKLVQLYGVC 464
Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737
+ ++TEY+ +G L +LR R + + + + A+ YLE+K +H ++
Sbjct 465 TKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAA 524
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV---ERIP--WLAPECLPGGANSLS 792
RN L+ G+ +K+SD G+ L E + P W PE L + S
Sbjct 525 RNCLVNDQGV-------VKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVL--MYSKFS 575
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQ--RQHRLPEPSCPQLATLTSQCL 849
+ D W FG + EI G+ P + + SE EH Q R +R P + ++ T+ C
Sbjct 576 SKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYR-PHLASERVYTIMYSCW 634
Query 850 TYEPTQRPSFRTILRDL 866
+ +RPSF+ +L ++
Sbjct 635 HEKADERPSFKILLSNI 651
>sp|Q98949|TYRO3_CHICK Tyrosine-protein kinase receptor TYRO3
OS=Gallus gallus OX=9031 GN=TYRO3 PE=1 SV=1
Length=873
Score = 133 bits (334), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 96/274 (35%), Positives = 134/274 (49%), Gaps = 28/274 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHI 959
R LG+G FG V +DG+ + VAVK LKAD + +E ++ H H+
Sbjct 509 RMLGKGEFGSVREALLK-LDDGSFQKVAVKMLKADIFTSTDIEEFLREAACMKEFDHPHV 567
Query 960 IKYKGCC-EDQGEKSLQLVMEYVPL---GSLRDYLPRHSIG-------LAQLLLFAQQIC 1008
K G + + L + M +P G L +L IG L LL F I
Sbjct 568 TKLIGVSLRSRPKGRLPIPMVILPFMKHGDLHAFLLMSRIGENPFNLPLQTLLKFMIDIA 627
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
GM YL ++++IHRDLAARN +LD + V + DFGL+K + G +YYR PV W
Sbjct 628 SGMEYLSSKNFIHRDLAARNCMLDENMNVSVADFGLSKKIYSG-DYYRQGCASKLPVKWL 686
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A E L + + SDVW+FGVT++E++T Q+P GI + + L
Sbjct 687 ALESLADNLYTTHSDVWAFGVTMWEIVTR---GQTP------YAGIENAE-----IYNYL 732
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
G RL +P +C +VY LM CW E RP+F
Sbjct 733 ISGNRLKQPPECLEDVYDLMCRCWHPEPKLRPSF 766
Score = 73.6 bits (179), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 78/291 (27%), Positives = 129/291 (44%), Gaps = 41/291 (14%)
Query 632 DRGQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PE 682
D G +V +K+L + DI F A+ M + H H+ + GV +R P
Sbjct 527 DDGSFQKVAVKMLKADIFTSTDIE-EFLREAACMKEFDHPHVTKLIGVSLRSRPKGRLPI 585
Query 683 NIMVTEYVEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737
+++ +++HG L +L R ++P+ + +AS + YL +KN +H ++
Sbjct 586 PMVILPFMKHGDLHAFLLMSRIGENPFNLPLQTLLKFMIDIASGMEYLSSKNFIHRDLAA 645
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIP--WLAPECLPGGANSL 791
RN +L + + ++D G+ G R+ ++P WLA E L N
Sbjct 646 RNCMLDE-------NMNVSVADFGLSKKIYSGDYYRQGCASKLPVKWLALESL--ADNLY 696
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCPQ-LATLTSQCL 849
+T D W FG T+ EI G+ P +E ++ +RL + P C + + L +C
Sbjct 697 TTHSDVWAFGVTMWEIVTRGQTPYAGIENAEIYNYLISGNRLKQPPECLEDVYDLMCRCW 756
Query 850 TYEPTQRPSFRTILRDLT----RLQPHNLA-DVLTVN----PDSPASDPTV 891
EP RPSF + L R+ +L+ D L VN +S SDP V
Sbjct 757 HPEPKLRPSFGVLRSQLEMIRGRMSTLSLSQDPLYVNIGKDKESSVSDPAV 807
>sp|Q9Z139|ROR1_MOUSE Inactive tyrosine-protein kinase transmembrane
receptor ROR1 OS=Mus musculus OX=10090 GN=Ror1 PE=2 SV=2
Length=937
Score = 133 bits (334), Expect = 4e-30, Method: Compositional matrix adjust.
Identities = 86/288 (30%), Positives = 141/288 (49%), Gaps = 37/288 (13%)
Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
++ + +LGE FGK+ + Y P D ++VA+K LK PQ + ++QE ++ L+
Sbjct 473 VRFMEELGECTFGKIYKGHLYLPGMD-HAQLVAIKTLKDYNNPQQWTEFQQEASLMAELH 531
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ------------ 999
H +I+ G E+ + ++ EY+ G L ++L P +G +
Sbjct 532 HPNIVCLLGAVTQ--EQPVCMLFEYMNQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDH 589
Query 1000 --LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
L A QI GM YL + ++H+DLAARN+L+ VKI D GL++ + +YYRV
Sbjct 590 GDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSA-DYYRV 648
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
+ P+ W PE + KF SD+WSFGV L+E+ + G +
Sbjct 649 QSKSSLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSF---------GLQPYYGFSNQ 699
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + E++ + + LP + CP +Y LM CW S RP F+++
Sbjct 700 E-----VIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDI 742
Score = 73.2 bits (178), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 73/295 (25%), Positives = 122/295 (41%), Gaps = 52/295 (18%)
Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651
+ LG+ T +Y+G L +PG D Q L + + D ++
Sbjct 476 MEELGECTFGKIYKGHL------------------YLPGMDHAQ-LVAIKTLKDYNNPQQ 516
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711
F + ASLM+++ H ++ + G + M+ EY+ G L +L H +
Sbjct 517 WTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYMNQGDLHEFLIMRSPHSDVGCS 576
Query 712 ----------------MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+ +A Q+A+ + YL + VH ++ RNIL+ G +
Sbjct 577 SDEDGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILI-------GEQLHV 629
Query 756 KLSDPGVGLGALSRE-ERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
K+SD G+ S + RV+ I W+ PE + G S+ D W FG L EI
Sbjct 630 KISDLGLSREIYSADYYRVQSKSSLPIRWMPPEAIMYG--KFSSDSDIWSFGVVLWEIFS 687
Query 810 DGEAPLQSRSPSEKEHFYQRQHRLP--EPSCPQLATLTSQCLTYEPTQRPSFRTI 862
G P S E +++ LP E P++ +L ++C P++RP F+ I
Sbjct 688 FGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDI 742
>sp|Q01973|ROR1_HUMAN Inactive tyrosine-protein kinase transmembrane
receptor ROR1 OS=Homo sapiens OX=9606 GN=ROR1 PE=1 SV=2
Length=937
Score = 133 bits (334), Expect = 4e-30, Method: Compositional matrix adjust.
Identities = 93/331 (28%), Positives = 156/331 (47%), Gaps = 38/331 (11%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV-S 912
Q+ S + R ++ N+ ++ +N P S ++ + +LGE FGK+
Sbjct 431 NQKSSSAPVQRQPKHVRGQNV-EMSMLNAYKPKSKAKELPLSAVRFMEELGECAFGKIYK 489
Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972
+ Y P D ++VA+K LK PQ + ++QE ++ L+H +I+ G E+
Sbjct 490 GHLYLPGMDH-AQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQ--EQ 546
Query 973 SLQLVMEYVPLGSLRDYL----PRHSIGLAQ--------------LLLFAQQICEGMAYL 1014
+ ++ EY+ G L ++L P +G + L A QI GM YL
Sbjct 547 PVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLHIAIQIAAGMEYL 606
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+ ++H+DLAARN+L+ VKI D GL++ + +YYRV+ P+ W PE +
Sbjct 607 SSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSA-DYYRVQSKSLLPIRWMPPEAIM 665
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SD+WSFGV L+E+ + G + + + E++ + + L
Sbjct 666 YGKFSSDSDIWSFGVVLWEIFSF---------GLQPYYGFSNQE-----VIEMVRKRQLL 711
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P + CP +Y LM CW S RP F+++
Sbjct 712 PCSEDCPPRMYSLMTECWNEIPSRRPRFKDI 742
Score = 74.3 bits (181), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 71/277 (26%), Positives = 119/277 (43%), Gaps = 34/277 (12%)
Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTH 669
+E G+ GK+ +PG D Q L + + D ++ F + ASLM+++ H +
Sbjct 476 MEELGECAFGKIYKGHLYLPGMDHAQ-LVAIKTLKDYNNPQQWTEFQQEASLMAELHHPN 534
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK----------------MV 713
+ + G + M+ EY+ G L +L H + +
Sbjct 535 IVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLH 594
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-ER 772
+A Q+A+ + YL + VH ++ RNIL+ G +K+SD G+ S + R
Sbjct 595 IAIQIAAGMEYLSSHFFVHKDLAARNILI-------GEQLHVKISDLGLSREIYSADYYR 647
Query 773 VER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
V+ I W+ PE + G S+ D W FG L EI G P S E
Sbjct 648 VQSKSLLPIRWMPPEAIMYG--KFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMV 705
Query 828 QRQHRLP--EPSCPQLATLTSQCLTYEPTQRPSFRTI 862
+++ LP E P++ +L ++C P++RP F+ I
Sbjct 706 RKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDI 742
>sp|Q99ML2|TNK1_MOUSE Non-receptor tyrosine-protein kinase TNK1
OS=Mus musculus OX=10090 GN=Tnk1 PE=1 SV=2
Length=666
Score = 131 bits (330), Expect = 4e-30, Method: Compositional matrix adjust.
Identities = 94/277 (34%), Positives = 135/277 (49%), Gaps = 28/277 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-----WKQEIDILRTLYHE 957
LG G FG V + G VAVK+L+ GP+ G + +E+ ++ L H
Sbjct 122 LGSGCFGVVHRGLWT-LPSGQSIPVAVKSLRV--GPEGPMGTELGDFLREVSVMMKLEHP 178
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLR----DYLPRHSIGLAQLLLFAQQICEGMAY 1013
H+++ G Q LQ+VME PLGSL P + +A L LF +Q+ MAY
Sbjct 179 HVLRLHGLVLGQ---PLQMVMELAPLGSLHARLTAPAPTPPLPVALLCLFLRQLAGAMAY 235
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
L + +HRDLA RN+LL + R++K+ DFGL + + Y + P W APE L
Sbjct 236 LGSCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESL 295
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
++ F ASDVW FGVTL+E+ + + + G L L L + R
Sbjct 296 RQGAFSSASDVWMFGVTLWEMFSGGEEPWA-------------GVPPYLILQRLEKDRAR 342
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
LP+P C +Y L CW + RP+F NL +L+
Sbjct 343 LPKPPLCSRALYSLALRCWAPHPADRPSFSNLEGLLQ 379
Score = 67.4 bits (163), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 71/221 (32%), Positives = 103/221 (47%), Gaps = 24/221 (11%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV--WLRRERGHVPMAWKM 712
F S+M ++ H H+ +HG+ + P MV E G L +P+A
Sbjct 165 FLREVSVMMKLEHPHVLRLHGLVLGQPLQ-MVMELAPLGSLHARLTAPAPTPPLPVALLC 223
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV--GLGALSRE 770
+ +QLA A++YL + LVH ++ RN+LLA + IK++D G+ LG +R
Sbjct 224 LFLRQLAGAMAYLGSCGLVHRDLATRNLLLA-------SPRMIKVADFGLVRPLGG-ARG 275
Query 771 ERVERIP------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK- 823
V P W APE L GA S+A D W FG TL E+ GE P P
Sbjct 276 RYVMGGPRPIPYAWCAPESLRQGA--FSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLIL 333
Query 824 EHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTI 862
+ + + RLP+P C + L +L +C P RPSF +
Sbjct 334 QRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFSNL 374
>sp|P00543|FES_FSVST Tyrosine-protein kinase transforming protein
Fes OS=Feline sarcoma virus (strain Snyder-Theilen) OX=11780
GN=V-FES PE=3 SV=1
Length=477
Score = 129 bits (323), Expect = 5e-30, Method: Compositional matrix adjust.
Identities = 91/310 (29%), Positives = 146/310 (47%), Gaps = 24/310 (8%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
QP + +N P D V + L +G G+FG+V + +VAV
Sbjct 190 QPLTKKSGIVLNRAVP-KDKWVLNHEDLVLGEQIGRGNFGEV----FSGRLRADNTLVAV 244
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K+ + P ++ + QE IL+ H +I++ G C + + + +VME V G +
Sbjct 245 KSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVCTQK--QPIYIVMELVQGGDFLTF 302
Query 990 LPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
L + + LL GM YL ++ IHRDLAARN L+ ++KI DFG+++
Sbjct 303 LRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSRE 362
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+G Y PV W APE L ++ SDVWSFG+ L+E + +S P
Sbjct 363 EADG-VYAASGGLRLVPVKWTAPEALNYGRYSSESDVWSFGILLWETFS-LGASPYP--- 417
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
++ + E +E+G RLP P+ CP V+ LM+ CW E RP+F
Sbjct 418 ----------NLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAFYQ 467
Query 1168 ILKTVHEKYQ 1177
L+++ ++++
Sbjct 468 ELQSIRKRHR 477
Score = 99.4 bits (246), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 81/285 (28%), Positives = 127/285 (45%), Gaps = 40/285 (14%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
+G+G V+ GRLR + + LV ++ + L P DI
Sbjct 221 QIGRGNFGEVFSGRLRADNT-------------LVA-------VKSCRETLPP---DIKA 257
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F + A ++ Q SH ++ + GVC + +V E V+ G +LR E + M +
Sbjct 258 KFLQEAKILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQ 317
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGAL 767
+ A+ + YLE+K +H ++ RN L+ + +K+SD G+ G+ A
Sbjct 318 MVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNV-------LKISDFGMSREEADGVYAA 370
Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
S R+ + W APE L G S+ D W FG L E G +P + S + F
Sbjct 371 SGGLRLVPVKWTAPEALNYG--RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFV 428
Query 828 QRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
++ RLP P CP + L QC YEP QRPSF ++L ++
Sbjct 429 EKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAFYQELQSIR 473
>sp|P14234|FGR_MOUSE Tyrosine-protein kinase Fgr OS=Mus musculus
OX=10090 GN=Fgr PE=1 SV=2
Length=517
Score = 129 bits (324), Expect = 6e-30, Method: Compositional matrix adjust.
Identities = 88/273 (32%), Positives = 132/273 (48%), Gaps = 29/273 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LG G FG V L ++ + VAVK LK G + +E I++ L H+ ++
Sbjct 255 RRLGTGCFGDVWLGTWNCSTK-----VAVKTLKP--GTMSPKAFLEEAQIMKLLRHDKLV 307
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ E+ + +V E++ GSL D+L ++ L L+ A Q+ EGMAY+
Sbjct 308 QLYAVV---SEEPIYIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQVAEGMAYMERM 364
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+YIHRDL A N+L+ + KI DFGLA+ + + Y ++ P+ W APE +
Sbjct 365 NYIHRDLRAANILVGEYLICKIADFGLARLIEDNE--YNPQQGTKFPIKWTAPEAALFGR 422
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFG+ L EL+T + M + E +E G +P P
Sbjct 423 FTVKSDVWSFGILLTELITKGR--------------VPYPGMNNREVLEQVEHGYHMPCP 468
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
CP +Y +M+ W + RPTFE L L+
Sbjct 469 PGCPASLYEVMEQAWRLDPEERPTFEYLQSFLE 501
Score = 69.3 bits (168), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 63/233 (27%), Positives = 102/233 (44%), Gaps = 19/233 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P AF E A +M + H L ++ V P I VTE++ +G L
Sbjct 275 KVAVKTLKPGTMS-PKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYI-VTEFMCYGSLLD 332
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ G M +V +A Q+A ++Y+E N +H ++ NIL+ G K
Sbjct 333 FLKDREGQNLMLPHLVDMAAQVAEGMAYMERMNYIHRDLRAANILV-------GEYLICK 385
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E ++ I W APE G ++ + D W FG L E+ G
Sbjct 386 IADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKS--DVWSFGILLTELITKG 443
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTI 862
P + E + + +P P CP L + Q +P +RP+F +
Sbjct 444 RVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEVMEQAWRLDPEERPTFEYL 496
>sp|G5EE56|SRC1_CAEEL Tyrosine protein-kinase src-1 OS=Caenorhabditis
elegans OX=6239 GN=src-1 PE=1 SV=1
Length=533
Score = 129 bits (324), Expect = 7e-30, Method: Compositional matrix adjust.
Identities = 92/272 (34%), Positives = 135/272 (50%), Gaps = 31/272 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LG+G+FG+V + G E VA+K +K G + QE I++ H +++
Sbjct 266 RKLGDGNFGEVWYGKWR----GIVE-VAIKTMKP--GTMSPEAFLQEAQIMKQCDHPNLV 318
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQH 1018
K C E+ ++ EY+ GSL YL ++G+ L+ A QI GM YL +
Sbjct 319 KLYAVCTR--EEPFYIITEYMINGSLLQYLRTDGSTLGIQALVDMAAQIANGMMYLEERK 376
Query 1019 YIHRDLAARNVLLDNDR----LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+HRDLAARNVL+ + +VK+ DFGLA+ + E + Y R P+ W APE
Sbjct 377 LVHRDLAARNVLVGDKISGVPVVKVADFGLARKLME-EDIYEARTGAKFPIKWTAPEAAT 435
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
F SDVWS+G+ LYE++T Q P M + E +E G R+
Sbjct 436 CGNFTVKSDVWSYGILLYEIMT---KGQVPYPG-----------MHNREVVEQVELGYRM 481
Query 1135 PRPDKCPCEVY-HLMKNCWETEASFRPTFENL 1165
P P CP ++Y ++ CW+ RPTF+ L
Sbjct 482 PMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTL 513
Score = 91.7 bits (226), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 64/235 (27%), Positives = 109/235 (46%), Gaps = 15/235 (6%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+ V +K + P AF + A +M Q H +L ++ VC R ++TEY+ +G L
Sbjct 285 VEVAIKTMKPGTMSPE-AFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLL 343
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+LR + + + + +A Q+A+ + YLE + LVH ++ RN+L +G P +K
Sbjct 344 QYLRTDGSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVL---VGDKISGVPVVK 400
Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
++D G+ + + R I W APE G + + D W +G L EI
Sbjct 401 VADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCG--NFTVKSDVWSYGILLYEIMTK 458
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ--LATLTSQCLTYEPTQRPSFRTI 862
G+ P E + +R+P P CP+ + +C P +RP+F T+
Sbjct 459 GQVPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTL 513
>sp|P42680|TEC_HUMAN Tyrosine-protein kinase Tec OS=Homo sapiens
OX=9606 GN=TEC PE=1 SV=2
Length=631
Score = 130 bits (327), Expect = 8e-30, Method: Compositional matrix adjust.
Identities = 89/277 (32%), Positives = 136/277 (49%), Gaps = 30/277 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+R+LG G FG V L + VA+KA++ G + +E ++ L H +
Sbjct 373 MRELGSGLFGVVRLGKWRAQYK-----VAIKAIRE--GAMCEEDFIEEAKVMMKLTHPKL 425
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQ 1017
++ G C Q K + +V E++ G L ++L + ++ LL Q +CEGM YL
Sbjct 426 VQLYGVCTQQ--KPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERN 483
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+IHRDLAARN L+ +VK+ DFG+A+ V + Y PV W PE +
Sbjct 484 SFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQ--YTSSSGAKFPVKWCPPEVFNYSR 541
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFGV ++E+ T + P K+ T + ++ RG RL +P
Sbjct 542 FSSKSDVWSFGVLMWEVFTE---GRMPFEKY-----------TNYEVVTMVTRGHRLYQP 587
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
VY +M CW+ + RP+FE+L L+T+ E
Sbjct 588 KLASNYVYEVMLRCWQEKPEGRPSFEDL---LRTIDE 621
Score = 94.4 bits (233), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 59/222 (27%), Positives = 102/222 (46%), Gaps = 16/222 (7%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F E A +M +++H L ++GVC + +VTE++E G L +LR+ +GH + +
Sbjct 410 FIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSM 469
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
Q + + YLE + +H ++ RN L++ G+ +K+SD G+ L +
Sbjct 470 CQDVCEGMEYLERNSFIHRDLAARNCLVSEAGV-------VKVSDFGMARYVLDDQYTSS 522
Query 775 R-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
+ W PE + S+ D W FG + E+ +G P + + E R
Sbjct 523 SGAKFPVKWCPPEVF--NYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTR 580
Query 830 QHRLPEPSCPQ--LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
HRL +P + + +C +P RPSF +LR + L
Sbjct 581 GHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDEL 622
>sp|Q13470|TNK1_HUMAN Non-receptor tyrosine-protein kinase TNK1
OS=Homo sapiens OX=9606 GN=TNK1 PE=1 SV=3
Length=666
Score = 130 bits (327), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 96/277 (35%), Positives = 136/277 (49%), Gaps = 29/277 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-----WKQEIDILRTLYHE 957
LG G FG V + G VAVK+L+ GP+ G + +E+ ++ L H
Sbjct 122 LGSGCFGVVHRGLWT-LPSGKSVPVAVKSLR--VGPEGPMGTELGDFLREVSVMMNLEHP 178
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAY 1013
H+++ G Q LQ+VME PLGSL L P + +A L LF +Q+ MAY
Sbjct 179 HVLRLHGLVLGQ---PLQMVMELAPLGSLHARLTAPAPTPPLLVALLCLFLRQLAGAMAY 235
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
L A+ +HRDLA RN+LL + R +K+ DFGL + + Y + P W APE L
Sbjct 236 LGARGLVHRDLATRNLLLASPRTIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESL 295
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ F ASDVW FGVTL+E+ + + + +L L + LE R
Sbjct 296 RHGAFSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLIL--------------QRLEDRAR 341
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
LPRP C +Y L CW + RP+F +L +L+
Sbjct 342 LPRPPLCSRALYSLALRCWAPHPADRPSFSHLEGLLQ 378
Score = 69.7 bits (169), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 71/217 (33%), Positives = 99/217 (46%), Gaps = 23/217 (11%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F S+M + H H+ +HG+ + P MV E G L L P+ ++
Sbjct 165 FLREVSVMMNLEHPHVLRLHGLVLGQPLQ-MVMELAPLGSLHARLTAPAPTPPLLVALLC 223
Query 715 A--QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV--GLGALSRE 770
+QLA A++YL + LVH ++ RN+LLA + IK++D G+ LG +R
Sbjct 224 LFLRQLAGAMAYLGARGLVHRDLATRNLLLA-------SPRTIKVADFGLVRPLGG-ARG 275
Query 771 ERVERIP------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
V P W APE L GA S+A D W FG TL E+ GE P P
Sbjct 276 RYVMGGPRPIPYAWCAPESLRHGA--FSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLIL 333
Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSF 859
+ + RLP P C + L +L +C P RPSF
Sbjct 334 QRLEDRARLPRPPLCSRALYSLALRCWAPHPADRPSF 370
>sp|P08922|ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS
OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3
Length=2347
Score = 132 bits (332), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 97/278 (35%), Positives = 139/278 (50%), Gaps = 32/278 (12%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG G FG+V D G+GE+ VAVK LK Q + + +E ++ H +I+
Sbjct 1951 LGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNIL 2010
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--------AQLLLFAQQICEGMA 1012
K G C + +++E + G L YL + + L+ I +G
Sbjct 2011 KQLGVCLLNEPQ--YIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCV 2068
Query 1013 YLHAQHYIHRDLAARNVLLD-----NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
YL H+IHRDLAARN L+ + R+VKIGDFGLA+ + + ++YYR R +G PV W
Sbjct 2069 YLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYK-NDYYRKRGEGLLPVRW 2127
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE L + F SDVWSFG+ ++E+LT Q P A + VL
Sbjct 2128 MAPESLMDGIFTTQSDVWSFGILIWEILTL--GHQPYP---------AHSNLDVLN---Y 2173
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
++ G RL P CP ++++LM CW E RPTF +
Sbjct 2174 VQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRI 2211
Score = 83.6 bits (205), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 69/247 (28%), Positives = 113/247 (46%), Gaps = 21/247 (9%)
Query 636 ELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
E++V +K L D + F + A LMS+ +H ++ GVC+ ++ E +E G
Sbjct 1974 EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGD 2033
Query 695 LDVWLRRERGHV------PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
L +LR+ R + + + ++ YLE + +H ++ RN L++ +
Sbjct 2034 LLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVS---VK 2090
Query 749 EGTSP-FIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFG 801
+ TSP +K+ D G+ + +R + W+APE L G +T D W FG
Sbjct 2091 DYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGI--FTTQSDVWSFG 2148
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
+ EI G P + S + ++ Q RL P +CP L L +QC EP QRP+F
Sbjct 2149 ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTF 2208
Query 860 RTILRDL 866
I L
Sbjct 2209 HRIQDQL 2215
>sp|Q8CBF3|EPHB1_MOUSE Ephrin type-B receptor 1 OS=Mus musculus
OX=10090 GN=Ephb1 PE=1 SV=1
Length=984
Score = 131 bits (330), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 82/279 (29%), Positives = 141/279 (51%), Gaps = 23/279 (8%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTL 954
++K +G G FG+V Y G E+ VA+K LKA + R + E I+
Sbjct 618 FVKIEEVIGAGEFGEV--YKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQF 675
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMA 1012
H +II+ +G + + ++ E++ G+L +L ++ + QL+ + I GM
Sbjct 676 DHPNIIRLEGVVTKS--RPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMK 733
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAP 1070
YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G PV W AP
Sbjct 734 YLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAP 793
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E + KF ASDVWS+G+ ++E+++ + M+ + +E+
Sbjct 794 EAIAYRKFTSASDVWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIEQ 839
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
RLP P CP ++ LM +CW+ + + RP F ++ L
Sbjct 840 DYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTL 878
Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 81/315 (26%), Positives = 141/315 (45%), Gaps = 50/315 (16%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653
+G G VY+GRL++ PG+ +E+ V +K L + +
Sbjct 625 IGAGEFGEVYKGRLKL------------------PGK---REIYVAIKTLKAGYSEKQRR 663
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F AS+M Q H ++ + GV + +++TE++E+G LD +LR+ G + +
Sbjct 664 DFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVG 723
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
+ + +A+ + YL N VH ++ RNIL+ ++ K+SD GL +++
Sbjct 724 MLRGIAAGMKYLSEMNYVHRDLAARNILV-------NSNLVCKVSD--FGLSRYLQDDTS 774
Query 774 E---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ +IP W APE + ++A D W +G + E+ GE P S +
Sbjct 775 DPTYTSSLGGKIPVRWTAPEAI--AYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQD 832
Query 823 KEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVL 878
+ ++ +RLP P CP L L C + RP F I+ L ++ P +L V
Sbjct 833 VINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVA 892
Query 879 TVN--PDSPASDPTV 891
T+ P P D ++
Sbjct 893 TITAVPSQPLLDRSI 907
>sp|P09759|EPHB1_RAT Ephrin type-B receptor 1 OS=Rattus norvegicus
OX=10116 GN=Ephb1 PE=1 SV=2
Length=984
Score = 131 bits (330), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 83/279 (30%), Positives = 142/279 (51%), Gaps = 23/279 (8%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTL 954
++K +G G FG+V Y G E+ VA+K LKA + R + E I+
Sbjct 618 FVKIEEVIGAGEFGEV--YKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQF 675
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMA 1012
H +II+ +G + + ++ E++ G+L +L ++ + QL+ + I GM
Sbjct 676 DHPNIIRLEGVVTKS--RPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMK 733
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAP 1070
YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G PV W AP
Sbjct 734 YLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAP 793
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E + KF ASDVWS+G+ ++E+++ + P M+ + +E+
Sbjct 794 EAIAYRKFTSASDVWSYGIVMWEVMSF---GERP-----------YWDMSNQDVINAIEQ 839
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
RLP P CP ++ LM +CW+ + + RP F ++ L
Sbjct 840 DYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTL 878
Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 81/315 (26%), Positives = 141/315 (45%), Gaps = 50/315 (16%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653
+G G VY+GRL++ PG+ +E+ V +K L + +
Sbjct 625 IGAGEFGEVYKGRLKL------------------PGK---REIYVAIKTLKAGYSEKQRR 663
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F AS+M Q H ++ + GV + +++TE++E+G LD +LR+ G + +
Sbjct 664 DFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVG 723
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
+ + +A+ + YL N VH ++ RNIL+ ++ K+SD GL +++
Sbjct 724 MLRGIAAGMKYLSEMNYVHRDLAARNILV-------NSNLVCKVSD--FGLSRYLQDDTS 774
Query 774 E---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ +IP W APE + ++A D W +G + E+ GE P S +
Sbjct 775 DPTYTSSLGGKIPVRWTAPEAI--AYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQD 832
Query 823 KEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVL 878
+ ++ +RLP P CP L L C + RP F I+ L ++ P +L V
Sbjct 833 VINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVA 892
Query 879 TVN--PDSPASDPTV 891
T+ P P D ++
Sbjct 893 TITAVPSQPLLDRSI 907
>sp|P09769|FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo sapiens
OX=9606 GN=FGR PE=1 SV=2
Length=529
Score = 128 bits (322), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 89/273 (33%), Positives = 131/273 (48%), Gaps = 29/273 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LG G FG V L ++ + VAVK LK G + +E +++ L H+ ++
Sbjct 267 RRLGTGCFGDVWLGTWNGSTK-----VAVKTLKP--GTMSPKAFLEEAQVMKLLRHDKLV 319
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ E+ + +V E++ GSL D+L + L QL+ A Q+ EGMAY+
Sbjct 320 QLYAVVS---EEPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERM 376
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+YIHRDL A N+L+ KI DFGLA+ + + + Y + P+ W APE +
Sbjct 377 NYIHRDLRAANILVGERLACKIADFGLARLIKD--DEYNPCQGSKFPIKWTAPEAALFGR 434
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFG+ L EL+T I M + E +E+G +P P
Sbjct 435 FTIKSDVWSFGILLTELITKGR--------------IPYPGMNKREVLEQVEQGYHMPCP 480
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
CP +Y M+ W + RPTFE L L+
Sbjct 481 PGCPASLYEAMEQTWRLDPEERPTFEYLQSFLE 513
Score = 70.1 bits (170), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 80/313 (26%), Positives = 129/313 (41%), Gaps = 49/313 (16%)
Query 560 NLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEG 619
NL+I P+TL L++ ++ + + IT LG G +V+ G GS
Sbjct 235 NLLIAPCTIMKPQTLGLAKDAWE-ISRSSITLERRLGTGCFGDVWLGTWN--GS------ 285
Query 620 KMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR 679
+V +K L P AF E A +M + H L ++ V
Sbjct 286 -----------------TKVAVKTLKPGTMS-PKAFLEEAQVMKLLRHDKLVQLYAVVSE 327
Query 680 GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGR 738
P I VTE++ HG L +L+ G ++V +A Q+A ++Y+E N +H ++
Sbjct 328 EPIYI-VTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAA 386
Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSL 791
NIL+ G K++D GL L +++ I W APE G ++
Sbjct 387 NILV-------GERLACKIAD--FGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGRFTI 437
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCL 849
+ D W FG L E+ G P + E ++ + +P P CP L Q
Sbjct 438 KS--DVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTW 495
Query 850 TYEPTQRPSFRTI 862
+P +RP+F +
Sbjct 496 RLDPEERPTFEYL 508
>sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo sapiens
OX=9606 GN=EPHB1 PE=1 SV=1
Length=984
Score = 131 bits (329), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 82/279 (29%), Positives = 141/279 (51%), Gaps = 23/279 (8%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTL 954
++K +G G FG+V Y G E+ VA+K LKA + R + E I+
Sbjct 618 FVKIEEVIGAGEFGEV--YKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQF 675
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMA 1012
H +II+ +G + + ++ E++ G+L +L ++ + QL+ + I GM
Sbjct 676 DHPNIIRLEGVVTKS--RPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMK 733
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAP 1070
YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G PV W AP
Sbjct 734 YLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAP 793
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E + KF ASDVWS+G+ ++E+++ + M+ + +E+
Sbjct 794 EAIAYRKFTSASDVWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIEQ 839
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
RLP P CP ++ LM +CW+ + + RP F ++ L
Sbjct 840 DYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTL 878
Score = 94.7 bits (234), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 81/315 (26%), Positives = 141/315 (45%), Gaps = 50/315 (16%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653
+G G VY+GRL++ PG+ +E+ V +K L + +
Sbjct 625 IGAGEFGEVYKGRLKL------------------PGK---REIYVAIKTLKAGYSEKQRR 663
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F AS+M Q H ++ + GV + +++TE++E+G LD +LR+ G + +
Sbjct 664 DFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVG 723
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
+ + +A+ + YL N VH ++ RNIL+ ++ K+SD GL +++
Sbjct 724 MLRGIAAGMKYLAEMNYVHRDLAARNILV-------NSNLVCKVSD--FGLSRYLQDDTS 774
Query 774 E---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ +IP W APE + ++A D W +G + E+ GE P S +
Sbjct 775 DPTYTSSLGGKIPVRWTAPEAI--AYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQD 832
Query 823 KEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVL 878
+ ++ +RLP P CP L L C + RP F I+ L ++ P +L V
Sbjct 833 VINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVA 892
Query 879 TVN--PDSPASDPTV 891
T+ P P D ++
Sbjct 893 TITAVPSQPLLDRSI 907
>sp|Q91736|EPB1B_XENLA Ephrin type-B receptor 1-B (Fragment) OS=Xenopus
laevis OX=8355 GN=ephb1-b PE=1 SV=1
Length=902
Score = 130 bits (328), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 73/247 (30%), Positives = 129/247 (52%), Gaps = 20/247 (8%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VA+K LKA + R + E I+ H +II+ +G + + ++ E++ G+L
Sbjct 566 VAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGAL 623
Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL
Sbjct 624 DSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGL 683
Query 1045 AKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
++ + + Y G PV W APE ++ KF ASDVWS+G+ ++E++++ +
Sbjct 684 SRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIRYRKFTSASDVWSYGIVMWEVMSYGER-- 741
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
M+ + +E+ RLP P CP ++ LM +CW+ + + RP F
Sbjct 742 ------------PYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRF 789
Query 1163 ENLIPIL 1169
++ L
Sbjct 790 GEIVNTL 796
Score = 90.5 bits (223), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 80/315 (25%), Positives = 140/315 (44%), Gaps = 50/315 (16%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653
+G G VY+GRL++ P + +E+ V +K L + +
Sbjct 543 IGAGEFGEVYKGRLKL------------------PSK---REISVAIKTLKAGYSEKQRR 581
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F AS+M Q H ++ + GV + +++TE++E+G LD +LR+ G + +
Sbjct 582 DFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVG 641
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
+ + +A+ + YL N VH ++ RNIL+ ++ K+SD GL +++
Sbjct 642 MLRGIAAGMKYLSEMNYVHRDLAARNILV-------NSNLVCKVSD--FGLSRYLQDDTS 692
Query 774 E---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ +IP W APE + ++A D W +G + E+ GE P S +
Sbjct 693 DPTYTSSLGGKIPVRWTAPEAI--RYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQD 750
Query 823 KEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVL 878
+ ++ +RLP P CP L L C + RP F I+ L ++ P +L V
Sbjct 751 VINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFGEIVNTLDKMIRNPASLKTVA 810
Query 879 TV--NPDSPASDPTV 891
T+ P P D ++
Sbjct 811 TIPAVPSQPLLDRSI 825
>sp|Q91048|PTK7_CHICK Inactive tyrosine-protein kinase 7 OS=Gallus
gallus OX=9031 GN=PTK7 PE=2 SV=1
Length=1051
Score = 130 bits (328), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 92/308 (30%), Positives = 141/308 (46%), Gaps = 29/308 (9%)
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE-MVAVKA 931
NL + A D F + L+ I LG G FG+V L D GE +V VK+
Sbjct 753 NLGSSSGASKRHSARDKMHFPRSNLQTITTLGRGEFGEVFLAKAKGAEDAEGEALVLVKS 812
Query 932 LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL- 990
L+ Q + +++E ++ L H ++++ G C + + +V+EYV LG L+ +L
Sbjct 813 LQTR-DEQLQLDFRREAEMFGKLNHVNVVRLLGLCREA--EPHYMVLEYVDLGDLKQFLR 869
Query 991 ---------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
+ + Q+ GM +L ++HRDLAARN L+ R VK+
Sbjct 870 ISKSKDESLKPQPLSTKHKVSLCTQVALGMEHLSNGRFVHRDLAARNCLVSAQRQVKVSA 929
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
L+K V EYY R+ P+ W PE + E +F SDVWSFGV ++E+ T +
Sbjct 930 LSLSKDV-YNSEYYHFRQ-AWIPLRWMPPEAVLEDEFSTKSDVWSFGVLMWEVFTQGEMP 987
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+P L G+ G+ +LP+P+ CP + LM+ CW RP+
Sbjct 988 YAPLADDEVLAGLKSGKT-------------KLPQPEGCPSRLTKLMQRCWAPSPKDRPS 1034
Query 1162 FENLIPIL 1169
F L L
Sbjct 1035 FSELAAAL 1042
Score = 70.9 bits (172), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 64/251 (25%), Positives = 105/251 (42%), Gaps = 21/251 (8%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
D E V++K L + L F A + +++H ++ + G+C + MV EY
Sbjct 799 AEDAEGEALVLVKSLQTRDEQLQLDFRREAEMFGKLNHVNVVRLLGLCREAEPHYMVLEY 858
Query 690 VEHGPLDVWLRRERGH------VPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNIL 741
V+ G L +LR + P++ K V+ Q+A + +L N VH ++ RN L
Sbjct 859 VDLGDLKQFLRISKSKDESLKPQPLSTKHKVSLCTQVALGMEHLSNGRFVHRDLAARNCL 918
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGA---NSLSTAMDKW 798
++ +K+S + + E R W+ +P A + ST D W
Sbjct 919 VS-------AQRQVKVSALSLSKDVYNSEYYHFRQAWIPLRWMPPEAVLEDEFSTKSDVW 971
Query 799 GFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQ 855
FG + E+ GE P + E + +LP+P CP +L L +C P
Sbjct 972 SFGVLMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLPQPEGCPSRLTKLMQRCWAPSPKD 1031
Query 856 RPSFRTILRDL 866
RPSF + L
Sbjct 1032 RPSFSELAAAL 1042
>sp|P14238|FES_FELCA Tyrosine-protein kinase Fes/Fps OS=Felis
catus OX=9685 GN=FES PE=3 SV=2
Length=820
Score = 130 bits (326), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 93/310 (30%), Positives = 149/310 (48%), Gaps = 24/310 (8%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
QP + +N P D V + L +G G+FG+V + D T +VAV
Sbjct 533 QPLTKKSGIVLNRAVP-KDKWVLNHEDLVLGEQIGRGNFGEV--FSGRLRADNT--LVAV 587
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K+ + P ++ + QE IL+ H +I++ G C + + + +VME V G +
Sbjct 588 KSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVCTQK--QPIYIVMELVQGGDFLTF 645
Query 990 LPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
L + + LL GM YL ++ IHRDLAARN L+ ++KI DFG+++
Sbjct 646 LRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSRE 705
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+G Y PV W APE L ++ SDVWSFG+ L+E + +S P
Sbjct 706 EADGI-YAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFS-LGASPYP--- 760
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
++ + E +E+G RLP P+ CP V+ LM+ CW E RP+F +
Sbjct 761 ----------NLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQ 810
Query 1168 ILKTVHEKYQ 1177
L+++ ++++
Sbjct 811 ELQSIRKRHR 820
Score = 99.4 bits (246), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 103/376 (27%), Positives = 161/376 (43%), Gaps = 67/376 (18%)
Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562
R F IE D + LEG G F S+ L LLR+ QP + I
Sbjct 500 RHFIIESADNLYRLEGDG--FASI----PLLVDHLLRS------------QQPLTKKSGI 541
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
++ RA P+ + ++ +++ +G+G V+ GRLR + +
Sbjct 542 VLN--RAVPKDKWV-------LNHEDLVLGEQIGRGNFGEVFSGRLRADNT--------- 583
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
LV ++ + L P DI F + A ++ Q SH ++ + GVC +
Sbjct 584 ----LVA-------VKSCRETLPP---DIKAKFLQEAKILKQYSHPNIVRLIGVCTQKQP 629
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+V E V+ G +LR E + M + + A+ + YLE+K +H ++ RN L+
Sbjct 630 IYIVMELVQGGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLV 689
Query 743 ARLGLAEGTSPFIKLSDPGV------GLGALSREERVERIPWLAPECLPGGANSLSTAMD 796
+ +K+SD G+ G+ A S R + W APE L G S+ D
Sbjct 690 TEKNV-------LKISDFGMSREEADGIYAASGGLRQVPVKWTAPEALNYG--RYSSESD 740
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPT 854
W FG L E G +P + S + F ++ RLP P CP + L QC YEP
Sbjct 741 VWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPG 800
Query 855 QRPSFRTILRDLTRLQ 870
QRPSF I ++L ++
Sbjct 801 QRPSFSAIYQELQSIR 816
>sp|Q22146|FRK1_CAEEL Fer-related kinase 1 OS=Caenorhabditis elegans
OX=6239 GN=frk-1 PE=1 SV=1
Length=390
Score = 125 bits (313), Expect = 3e-29, Method: Compositional matrix adjust.
Identities = 80/277 (29%), Positives = 137/277 (49%), Gaps = 27/277 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+ LGEG FG V + D G + VAVK ++A+ + R + +E ++R H+H++
Sbjct 135 KKLGEGAFGDVFIAELD---QGGKQEVAVKTMRAEATREARLRFMKEARLMRKYQHKHVV 191
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
K G E L +VMEY P GSL +L ++ + L + L F + +G+AYL I
Sbjct 192 KLIGVA--IHEHPLMIVMEYCPNGSLLSHLKKNKVSLIEKLRFTTEAADGIAYLERSKCI 249
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVFWYAPECLKEYKF 1078
HRD+AARN LL +KI DFG++ E ++++ P+ W APE ++E +
Sbjct 250 HRDIAARNCLLSAKNELKISDFGMSDNKDE------IKDETLEKVPIKWLAPETMQEKVY 303
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+ +D+W+FGV ++E+ + D ++ P G + +++ R+ PD
Sbjct 304 THKTDIWTFGVLVWEI--YSDGAEPYP-----------GLTKIQTRAKIVVNDYRMKMPD 350
Query 1139 KC-PCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
P + CW+ R T +++ L+ +E
Sbjct 351 GTHPTVADVVTGTCWQKNPEKRSTMDSIHKKLREFYE 387
Score = 78.6 bits (192), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 64/253 (25%), Positives = 117/253 (46%), Gaps = 25/253 (10%)
Query 625 DPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
D + D+G + V +K + + + L F + A LM + H H+ + GV +
Sbjct 144 DVFIAELDQGGKQEVAVKTMRAEATREARLRFMKEARLMRKYQHKHVVKLIGVAIHEHPL 203
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
++V EY +G L L++ + V + K+ + A ++YLE +H ++ RN LL+
Sbjct 204 MIVMEYCPNGSLLSHLKKNK--VSLIEKLRFTTEAADGIAYLERSKCIHRDIAARNCLLS 261
Query 744 RLGLAEGTSPFIKLSDPGVGLGALS-REERVERIP--WLAPECLPGGANSLSTAMDKWGF 800
+K+SD G+ ++E +E++P WLAPE + + T D W F
Sbjct 262 -------AKNELKISDFGMSDNKDEIKDETLEKVPIKWLAPETMQEKVYTHKT--DIWTF 312
Query 801 GATLLEICFDGEAP------LQSRSPSEKEHFYQRQHRLPEPSCPQLA-TLTSQCLTYEP 853
G + EI DG P +Q+R+ + + ++P+ + P +A +T C P
Sbjct 313 GVLVWEIYSDGAEPYPGLTKIQTRAKIVVNDY---RMKMPDGTHPTVADVVTGTCWQKNP 369
Query 854 TQRPSFRTILRDL 866
+R + +I + L
Sbjct 370 EKRSTMDSIHKKL 382
>sp|Q8BYG9|EPHAA_MOUSE Ephrin type-A receptor 10 OS=Mus musculus
OX=10090 GN=Epha10 PE=2 SV=2
Length=1007
Score = 130 bits (327), Expect = 3e-29, Method: Compositional matrix adjust.
Identities = 89/278 (32%), Positives = 128/278 (46%), Gaps = 23/278 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LG G FG + C G E+ VAV L+ C R + E L H HI
Sbjct 648 KSLGAGRFGTLCCGCLQ--LPGRQELPVAVHTLRDGCSDSQRLSFLAEALTLGQFDHSHI 705
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQ 1017
++ +G L +V EY+ LG+L D+L H L AQL+ + M YL
Sbjct 706 VRLEGVVTRG--NPLMIVTEYMNLGALDDFLRHHEGELVAAQLMGLLPGLASAMKYLSEM 763
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
Y+HR LAAR VL+ + L KI FG + + E G SP W APE L+
Sbjct 764 GYVHRGLAARRVLVSSGLLCKISGFG--RGPRDRAEAVYTTMSGRSPALWAAPETLQFGH 821
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F ASDVWSFG+ ++E++ + M+ + + +E G RLP P
Sbjct 822 FSSASDVWSFGIVMWEVMAFGER--------------PYWDMSGQDVIKAVEDGFRLPPP 867
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
CP +++ LM CW+ + S RP F + IL + ++
Sbjct 868 RNCPSQLHRLMLECWQKDPSERPRFSQIHSILSKMGQE 905
Score = 104 bits (260), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 91/275 (33%), Positives = 127/275 (46%), Gaps = 28/275 (10%)
Query 628 VPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+PGR QEL V + L D L+F A + Q H+H+ + GV RG ++V
Sbjct 665 LPGR---QELPVAVHTLRDGCSDSQRLSFLAEALTLGQFDHSHIVRLEGVVTRGNPLMIV 721
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TEY+ G LD +LR G + A M + LASA+ YL VH + R +L++ G
Sbjct 722 TEYMNLGALDDFLRHHEGELVAAQLMGLLPGLASAMKYLSEMGYVHRGLAARRVLVSS-G 780
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-----ERIP--WLAPECLPGGANSLSTAMDKWG 799
L K+S G G G R E V R P W APE L G S+A D W
Sbjct 781 L------LCKIS--GFGRGPRDRAEAVYTTMSGRSPALWAAPETLQFG--HFSSASDVWS 830
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRP 857
FG + E+ GE P S + + RLP P +CP QL L +C +P++RP
Sbjct 831 FGIVMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPSQLHRLMLECWQKDPSERP 890
Query 858 SFRTILRDLTRL----QPHNLADVLTVNPDSPASD 888
F I L+++ +P A + P +P +D
Sbjct 891 RFSQIHSILSKMGQEPEPSKCASTTCLRPPTPLAD 925
>sp|A0JM20|TYRO3_XENTR Tyrosine-protein kinase receptor TYRO3
OS=Xenopus tropicalis OX=8364 GN=tyro3 PE=2 SV=1
Length=881
Score = 130 bits (326), Expect = 3e-29, Method: Compositional matrix adjust.
Identities = 92/278 (33%), Positives = 134/278 (48%), Gaps = 30/278 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEH 958
R LG+G FG V D T + VAVK LKA+ C + +E ++ H +
Sbjct 507 RTLGKGEFGSVR-EAQLKMEDDTMQKVAVKMLKAEIFCSSDIEE-FLREAAFMKEFDHPN 564
Query 959 IIKYKGCCEDQGEKSL----QLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFAQQI 1007
+ K G K +++ ++ G L +L IG + L+ F I
Sbjct 565 VCKLIGVSLRSRTKGRLPVPMVILPFMKHGDLHTFLLMSRIGEEPIALPIQTLVRFMIDI 624
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
C GM YL ++++IHRDLA RN +L+ D V + DFGL+K + G +YYR PV W
Sbjct 625 CSGMEYLSSKNFIHRDLATRNCMLNEDMTVCVADFGLSKKIYSG-DYYRQGCASKLPVKW 683
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
A E L + + SDVW+FGVTL+E++T Q+P G+ + +
Sbjct 684 LALESLADNVYTVHSDVWAFGVTLWEIVTR---GQTP------YAGVENSE-----IYSY 729
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L G RL +P C E+Y +M CW TE RP+F +L
Sbjct 730 LTAGNRLKQPPDCLDELYEMMCQCWITEPKRRPSFVDL 767
Score = 74.3 bits (181), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 83/314 (26%), Positives = 132/314 (42%), Gaps = 57/314 (18%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S+L + Q++ T LG+G +V E +L KM+D D Q+
Sbjct 491 SKLKDVLIQQQQFTLGRTLGKGEFGSVREAQL-----------KMED--------DTMQK 531
Query 637 LRV-VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEY 689
+ V +LK DI F A+ M + H ++ + GV +R P +++ +
Sbjct 532 VAVKMLKAEIFCSSDIE-EFLREAAFMKEFDHPNVCKLIGVSLRSRTKGRLPVPMVILPF 590
Query 690 VEHGPLDVWLRRER-GHVPMAWKMVVAQQ----LASALSYLENKNLVHGNVCGRNILL-- 742
++HG L +L R G P+A + + + S + YL +KN +H ++ RN +L
Sbjct 591 MKHGDLHTFLLMSRIGEEPIALPIQTLVRFMIDICSGMEYLSSKNFIHRDLATRNCMLNE 650
Query 743 ------ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP--WLAPECLPGGANSLSTA 794
A GL++ + G R+ ++P WLA E L N +
Sbjct 651 DMTVCVADFGLSKK-----------IYSGDYYRQGCASKLPVKWLALESL--ADNVYTVH 697
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYE 852
D W FG TL EI G+ P SE + +RL +P +L + QC E
Sbjct 698 SDVWAFGVTLWEIVTRGQTPYAGVENSEIYSYLTAGNRLKQPPDCLDELYEMMCQCWITE 757
Query 853 PTQRPSFRTILRDL 866
P +RPSF + R L
Sbjct 758 PKRRPSFVDLKRRL 771
>sp|P16591|FER_HUMAN Tyrosine-protein kinase Fer OS=Homo sapiens
OX=9606 GN=FER PE=1 SV=2
Length=822
Score = 129 bits (325), Expect = 3e-29, Method: Compositional matrix adjust.
Identities = 91/277 (33%), Positives = 136/277 (49%), Gaps = 29/277 (10%)
Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG+G+FG+V Y T D T VAVK K D + + + QE IL+ H +I+K
Sbjct 569 LGKGNFGEV----YKGTLKDKTS--VAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVK 622
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHY 1019
G C + + + ++ME V G +L R + L QL+ F+ GM YL +++
Sbjct 623 LIGVCTQR--QPVYIIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLESKNC 680
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRDLAARN L+ + ++KI DFG+++ G Y P+ W APE L ++
Sbjct 681 IHRDLAARNCLVGENNVLKISDFGMSRQEDGG--VYSSSGLKQIPIKWTAPEALNYGRYS 738
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA-QGQMTVLRLTELLERGERLPRPD 1138
SDVWSFG+ L+E + +G+ MT + E +ERG R+ P
Sbjct 739 SESDVWSFGILLWETFS---------------LGVCPYPGMTNQQAREQVERGYRMSAPQ 783
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
CP ++ +M CW+ + RP F L L + K
Sbjct 784 HCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRK 820
Score = 89.7 bits (221), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 73/280 (26%), Positives = 127/280 (45%), Gaps = 40/280 (14%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LG+G VY+G L+ + S + K D +P QEL++
Sbjct 569 LGKGNFGEVYKGTLKDKTSVAVKTCKED-----LP-----QELKI--------------K 604
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F + A ++ Q H ++ + GVC + ++ E V G +LRR++ + + +
Sbjct 605 FLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQLVKF 664
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---GALSREE 771
+ A+ + YLE+KN +H ++ RN L+ G + +K+SD G+ G +
Sbjct 665 SLDAAAGMLYLESKNCIHRDLAARNCLV-------GENNVLKISDFGMSRQEDGGVYSSS 717
Query 772 RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
+++IP W APE L G S+ D W FG L E G P + + +R
Sbjct 718 GLKQIPIKWTAPEALNYG--RYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVER 775
Query 830 QHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLT 867
+R+ P CP+ ++ + +C Y+P RP F + ++LT
Sbjct 776 GYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELT 815
>sp|Q91735|EPHB3_XENLA Ephrin type-B receptor 3 OS=Xenopus laevis
OX=8355 GN=ephb3 PE=2 SV=1
Length=974
Score = 129 bits (325), Expect = 4e-29, Method: Compositional matrix adjust.
Identities = 79/273 (29%), Positives = 134/273 (49%), Gaps = 25/273 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDG--TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G FG+V C + VA+K LKA Q R + E I+ H +II
Sbjct 615 IGAGEFGEV---CRGKLKQAGRREQFVAIKTLKAGYTEQQRRDFLGEASIMGQFDHPNII 671
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018
+ +G + + ++ E++ G+L +L + + QL+ + I GM YL +
Sbjct 672 RLEGVVTR--SRPVMILTEFMENGALDSFLRMNDGQFTVIQLVGILRGIASGMKYLSEMN 729
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076
Y+HRDLAARN+L++++ + K+ DFGL++ + Y G P+ W APE +
Sbjct 730 YVHRDLAARNILVNSNLVCKVSDFGLSRFLENSRSDPTYTSALGGKIPIRWTAPEAISYR 789
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
KF ASDVWS+G+ ++E++++ + M+ + +E+ RLP
Sbjct 790 KFTSASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVINAIEQDYRLPP 835
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P CP ++ LM +CW + + RP F ++ L
Sbjct 836 PMDCPSALHQLMLDCWLRDRNLRPKFSQIVSSL 868
Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 68/241 (28%), Positives = 109/241 (45%), Gaps = 25/241 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F AS+M Q H ++ + GV R +++TE++E+G LD +LR G + + +
Sbjct 655 FLGEASIMGQFDHPNIIRLEGVVTRSRPVMILTEFMENGALDSFLRMNDGQFTVIQLVGI 714
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ +AS + YL N VH ++ RNIL+ ++ K+SD GL R +
Sbjct 715 LRGIASGMKYLSEMNYVHRDLAARNILV-------NSNLVCKVSD--FGLSRFLENSRSD 765
Query 775 ---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+IP W APE + ++A D W +G + E+ GE P S +
Sbjct 766 PTYTSALGGKIPIRWTAPEAI--SYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDV 823
Query 824 EHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
+ ++ +RLP P CP L L C + RP F I+ L +L N A + +
Sbjct 824 INAIEQDYRLPPPMDCPSALHQLMLDCWLRDRNLRPKFSQIVSSLDKL-IRNAASLKVTS 882
Query 882 P 882
P
Sbjct 883 P 883
>sp|P24348|LET23_CAEEL Receptor tyrosine-protein kinase let-23
OS=Caenorhabditis elegans OX=6239 GN=let-23 PE=1 SV=3
Length=1323
Score = 130 bits (326), Expect = 4e-29, Method: Compositional matrix adjust.
Identities = 91/274 (33%), Positives = 140/274 (51%), Gaps = 24/274 (9%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LG G FG V Y P ++ VA+K + D Q ++ ++ R L H+++
Sbjct 889 KKLGAGAFGTVFAGIYYPKRAKNVKIPVAIKVFQTD-QSQTDEMLEEATNMFR-LRHDNL 946
Query 960 IKYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHA 1016
+K G C D G L++V Y PLG+L+++L H ++G + +L+ QI GM YL
Sbjct 947 LKIIGFCMHDDG---LKIVTIYRPLGNLQNFLKLHKENLGAREQVLYCYQIASGMQYLEK 1003
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
Q +HRDLA RNVL+ V+I DFGL+K + + ++ G + W A E ++
Sbjct 1004 QRVVHRDLATRNVLVKKFNHVEITDFGLSKILKHDADSITIKS-GKVAIKWLAIEIFSKH 1062
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+ +ASDVW+FGVT +E++T QSP QG M+ + L+ G RL +
Sbjct 1063 CYTHASDVWAFGVTCWEIITF---GQSP----------YQG-MSTDSIHNFLKDGNRLSQ 1108
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
P C ++Y + CW + RP FE L K
Sbjct 1109 PPNCSQDLYQELLRCWMADPKSRPGFEILYERFK 1142
Score = 79.0 bits (193), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 67/242 (28%), Positives = 112/242 (46%), Gaps = 18/242 (7%)
Query 629 PGRDRGQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
P R + ++ V +KV D S D L E A+ M ++ H +L + G C+ +V
Sbjct 906 PKRAKNVKIPVAIKVFQTDQSQTDEML---EEATNMFRLRHDNLLKIIGFCMHDDGLKIV 962
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
T Y G L +L+ + ++ +++ Q+AS + YLE + +VH ++ RN+L+ +
Sbjct 963 TIYRPLGNLQNFLKLHKENLGAREQVLYCYQIASGMQYLEKQRVVHRDLATRNVLVKKFN 1022
Query 747 LAE----GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
E G S +K + + + +V I WLA E + + A D W FG
Sbjct 1023 HVEITDFGLSKILKHDADSITI----KSGKVA-IKWLAIEIF--SKHCYTHASDVWAFGV 1075
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCPQ-LATLTSQCLTYEPTQRPSFR 860
T EI G++P Q S +F + +RL + P+C Q L +C +P RP F
Sbjct 1076 TCWEIITFGQSPYQGMSTDSIHNFLKDGNRLSQPPNCSQDLYQELLRCWMADPKSRPGFE 1135
Query 861 TI 862
+
Sbjct 1136 IL 1137
>sp|Q2MHE4|HT1_ARATH Serine/threonine/tyrosine-protein kinase
HT1 OS=Arabidopsis thaliana OX=3702 GN=HT1 PE=1 SV=1
Length=390
Score = 124 bits (311), Expect = 4e-29, Method: Compositional matrix adjust.
Identities = 78/254 (31%), Positives = 125/254 (49%), Gaps = 25/254 (10%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
+MV + K + + +K E+ +L L+H +I+++ C + ++ EY+ G
Sbjct 113 KMVRIPTHKEETRAKLEQQFKSEVALLSRLFHPNIVQFIAAC--KKPPVYCIITEYMSQG 170
Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
+LR YL + +S+ + +L A I GM YLH+Q IHRDL + N+LL+++ VK+ D
Sbjct 171 NLRMYLNKKEPYSLSIETVLRLALDISRGMEYLHSQGVIHRDLKSNNLLLNDEMRVKVAD 230
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVF-WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100
FG + + E G+ + W APE +KE + DV+SFG+ L+EL T
Sbjct 231 FGTSCLETQCRE-----AKGNMGTYRWMAPEMIKEKPYTRKVDVYSFGIVLWELTTA--- 282
Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
+ QG V + E+ ER P P C + HL+K CW S RP
Sbjct 283 -----------LLPFQGMTPVQAAFAVAEKNERPPLPASCQPALAHLIKRCWSENPSKRP 331
Query 1161 TFENLIPILKTVHE 1174
F N++ +L+ E
Sbjct 332 DFSNIVAVLEKYDE 345
Score = 63.5 bits (153), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 61/250 (24%), Positives = 112/250 (45%), Gaps = 30/250 (12%)
Query 635 QELRVVLKVLDPSHHDIALA-----FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
Q V V P+H + A F +L+S++ H ++ C + P ++TEY
Sbjct 107 QRAVAVKMVRIPTHKEETRAKLEQQFKSEVALLSRLFHPNIVQFIAACKKPPVYCIITEY 166
Query 690 VEHGPLDVWL-RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ G L ++L ++E + + + +A ++ + YL ++ ++H ++ N+LL
Sbjct 167 MSQGNLRMYLNKKEPYSLSIETVLRLALDISRGMEYLHSQGVIHRDLKSNNLLL------ 220
Query 749 EGTSPFIKLSDPGVG-LGALSREER--VERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+K++D G L RE + + W+APE + + +D + FG L
Sbjct 221 -NDEMRVKVADFGTSCLETQCREAKGNMGTYRWMAPEMI--KEKPYTRKVDVYSFGIVLW 277
Query 806 EIC-----FDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEPTQRPS 858
E+ F G P+Q+ ++ R P P SC P LA L +C + P++RP
Sbjct 278 ELTTALLPFQGMTPVQAAFA-----VAEKNERPPLPASCQPALAHLIKRCWSENPSKRPD 332
Query 859 FRTILRDLTR 868
F I+ L +
Sbjct 333 FSNIVAVLEK 342
>sp|Q9UF33|EPHA6_HUMAN Ephrin type-A receptor 6 OS=Homo sapiens
OX=9606 GN=EPHA6 PE=1 SV=3
Length=1036
Score = 129 bits (324), Expect = 6e-29, Method: Compositional matrix adjust.
Identities = 94/342 (27%), Positives = 158/342 (46%), Gaps = 70/342 (20%)
Query 880 VNPDSPASDPTVFHKRYLKKI--------RDLGEGHFGKVSLYCYDPTND-GTGEM-VAV 929
++PD+ DP++ + K+I R +G G FG+V C G E+ VA+
Sbjct 607 IDPDT-YEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEV---CSGRLKTPGKREIPVAI 662
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ-------------------- 969
K LK + R + +E I+ H +II+ +G +
Sbjct 663 KTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFL 722
Query 970 --------------------GEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQI 1007
+ + +V+EY+ GSL +L +H + QL+ + I
Sbjct 723 NSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGI 782
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
GM YL Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W
Sbjct 783 ASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRW 842
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + KF ASD WS+G+ ++E++++ + P + E+ Q +L
Sbjct 843 TAPEAIAYRKFSSASDAWSYGIVMWEVMSY---GERP---YWEM----SNQDVILS---- 888
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+E G RLP P CP ++ LM +CW+ E + RP F +++ L
Sbjct 889 IEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFL 930
Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 88/341 (26%), Positives = 135/341 (40%), Gaps = 70/341 (21%)
Query 607 RLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQ 664
R+R+E G E G++ PG+ +E+ V +K L H D F AS+M Q
Sbjct 630 RIRIERVIGAGEFGEVCSGRLKTPGK---REIPVAIKTLKGGHMDRQRRDFLREASIMGQ 686
Query 665 VSHTHLAFVHGVCVR------------------------------------------GPE 682
H ++ + GV + G
Sbjct 687 FDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRP 746
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
++V EY+E+G LD +LR+ GH + + + + +AS + YL + VH ++ RNIL+
Sbjct 747 VMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILV 806
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIP--WLAPECLPGGANSLSTAM 795
++ K+SD G+ E +IP W APE + S+A
Sbjct 807 -------NSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAI--AYRKFSSAS 857
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEP 853
D W +G + E+ GE P S + + +RLP P CP L L C E
Sbjct 858 DAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKER 917
Query 854 TQRPSFRTILRDLTRL-----QPHNLADVLTVNPDSPASDP 889
RP F I+ L +L H L + + V P+SP P
Sbjct 918 NHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGEVP 958
>sp|P07332|FES_HUMAN Tyrosine-protein kinase Fes/Fps OS=Homo sapiens
OX=9606 GN=FES PE=1 SV=3
Length=822
Score = 129 bits (323), Expect = 6e-29, Method: Compositional matrix adjust.
Identities = 87/277 (31%), Positives = 138/277 (50%), Gaps = 23/277 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G+FG+V + D T +VAVK+ + P ++ + QE IL+ H +I++
Sbjct 567 IGRGNFGEV--FSGRLRADNT--LVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRL 622
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYI 1020
G C + + + +VME V G +L L LL GM YL ++ I
Sbjct 623 IGVCTQK--QPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCI 680
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARN L+ ++KI DFG+++ +G Y PV W APE L ++
Sbjct 681 HRDLAARNCLVTEKNVLKISDFGMSREEADG-VYAASGGLRQVPVKWTAPEALNYGRYSS 739
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWSFG+ L+E + +S P ++ + E +E+G RLP P+ C
Sbjct 740 ESDVWSFGILLWETFS-LGASPYP-------------NLSNQQTREFVEKGGRLPCPELC 785
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
P V+ LM+ CW E RP+F + L+++ ++++
Sbjct 786 PDAVFRLMEQCWAYEPGQRPSFSTIYQELQSIRKRHR 822
Score = 97.4 bits (241), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 81/285 (28%), Positives = 128/285 (45%), Gaps = 40/285 (14%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
+G+G V+ GRLR + + LV ++ + L P D+
Sbjct 566 QIGRGNFGEVFSGRLRADNT-------------LVA-------VKSCRETLPP---DLKA 602
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F + A ++ Q SH ++ + GVC + +V E V+ G +LR E + + +
Sbjct 603 KFLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQ 662
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGAL 767
+ A+ + YLE+K +H ++ RN L+ + +K+SD G+ G+ A
Sbjct 663 MVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNV-------LKISDFGMSREEADGVYAA 715
Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
S R + W APE L G S+ D W FG L E G +P + S + F
Sbjct 716 SGGLRQVPVKWTAPEALNYG--RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFV 773
Query 828 QRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
++ RLP P CP + L QC YEP QRPSF TI ++L ++
Sbjct 774 EKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQSIR 818
>sp|Q07494|EPHB1_CHICK Ephrin type-B receptor 1 (Fragment) OS=Gallus
gallus OX=9031 GN=EPHB1 PE=2 SV=2
Length=984
Score = 129 bits (324), Expect = 6e-29, Method: Compositional matrix adjust.
Identities = 81/279 (29%), Positives = 140/279 (50%), Gaps = 23/279 (8%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTL 954
++K +G G FG+V Y G E+ VA+K LKA + R + E I+
Sbjct 618 FVKIEEVIGAGEFGEV--YKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQF 675
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMA 1012
H +II+ +G + + ++ E++ G+L +L ++ + QL+ + I GM
Sbjct 676 DHPNIIRLEGVVTKS--RPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMK 733
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAP 1070
YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G PV W AP
Sbjct 734 YLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAP 793
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E + KF ASDVWS+G+ ++E+++ + M+ + +E+
Sbjct 794 EAIAYRKFTSASDVWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIEQ 839
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
RLP P CP ++ LM +CW+ + + RP ++ L
Sbjct 840 DYRLPPPMDCPAALHQLMLDCWQKDRNTRPRLAEIVNTL 878
Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 80/315 (25%), Positives = 140/315 (44%), Gaps = 50/315 (16%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653
+G G VY+GRL++ PG+ +E+ V +K L + +
Sbjct 625 IGAGEFGEVYKGRLKL------------------PGK---REIYVAIKTLKAGYSEKQRR 663
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F AS+M Q H ++ + GV + +++TE++E+G LD +LR+ G + +
Sbjct 664 DFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVG 723
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
+ + +A+ + YL N VH ++ RNIL+ ++ K+SD GL +++
Sbjct 724 MLRGIAAGMKYLAEMNYVHRDLAARNILV-------NSNLVCKVSD--FGLSRYLQDDTS 774
Query 774 E---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ +IP W APE + ++A D W +G + E+ GE P S +
Sbjct 775 DPTYTSSLGGKIPVRWTAPEAI--AYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQD 832
Query 823 KEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVL 878
+ ++ +RLP P CP L L C + RP I+ L ++ P +L V
Sbjct 833 VINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNTRPRLAEIVNTLDKMIRNPASLKTVA 892
Query 879 TVN--PDSPASDPTV 891
T+ P P D ++
Sbjct 893 TITAVPSQPLLDRSI 907
>sp|P54758|EPHA6_RAT Ephrin type-A receptor 6 OS=Rattus norvegicus
OX=10116 GN=Epha6 PE=2 SV=2
Length=1035
Score = 129 bits (324), Expect = 6e-29, Method: Compositional matrix adjust.
Identities = 94/342 (27%), Positives = 158/342 (46%), Gaps = 70/342 (20%)
Query 880 VNPDSPASDPTVFHKRYLKKI--------RDLGEGHFGKVSLYCYDPTND-GTGEM-VAV 929
++PD+ DP++ + K+I R +G G FG+V C G E+ VA+
Sbjct 606 IDPDT-YEDPSLAVHEFEKEIDPSRIRIERVIGAGEFGEV---CSGRLKTPGKREIPVAI 661
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ-------------------- 969
K LK + R + +E I+ H +II+ +G +
Sbjct 662 KTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFL 721
Query 970 --------------------GEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQI 1007
+ + +V+EY+ GSL +L +H + QL+ + I
Sbjct 722 NGIQAPHPVTAGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGI 781
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
GM YL Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W
Sbjct 782 ASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRW 841
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + KF ASDVWS+G+ ++E++++ + + E+ Q +L
Sbjct 842 TAPEAIAYRKFSSASDVWSYGIVMWEVMSYGER------PYWEM----SNQDVILS---- 887
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+E G RLP P CP ++ LM +CW+ E + RP F +++ L
Sbjct 888 IEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFL 929
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 88/341 (26%), Positives = 135/341 (40%), Gaps = 70/341 (21%)
Query 607 RLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQ 664
R+R+E G E G++ PG+ +E+ V +K L H D F AS+M Q
Sbjct 629 RIRIERVIGAGEFGEVCSGRLKTPGK---REIPVAIKTLKGGHMDRQRRDFLREASIMGQ 685
Query 665 VSHTHLAFVHGVCVR------------------------------------------GPE 682
H ++ + GV + G
Sbjct 686 FDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNGIQAPHPVTAGGSLPPRIPAGRP 745
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
++V EY+E+G LD +LR+ GH + + + + +AS + YL + VH ++ RNIL+
Sbjct 746 VMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILV 805
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIP--WLAPECLPGGANSLSTAM 795
++ K+SD G+ E +IP W APE + S+A
Sbjct 806 -------NSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAI--AYRKFSSAS 856
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEP 853
D W +G + E+ GE P S + + +RLP P C P L L C E
Sbjct 857 DVWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKER 916
Query 854 TQRPSFRTILRDLTRL-----QPHNLADVLTVNPDSPASDP 889
RP F I+ L +L H L + + V P+SP P
Sbjct 917 NHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGDVP 957
>sp|P00544|FGR_FSVGR Tyrosine-protein kinase transforming protein
Fgr OS=Feline sarcoma virus (strain Gardner-Rasheed) OX=11775
GN=V-FGR PE=3 SV=1
Length=545
Score = 126 bits (317), Expect = 6e-29, Method: Compositional matrix adjust.
Identities = 88/273 (32%), Positives = 129/273 (47%), Gaps = 29/273 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LG G FG V L ++ + VAVK LK G +E I++ L H+ ++
Sbjct 290 RRLGTGCFGDVWLGMWNGSTK-----VAVKTLKP--GTMSPKASLEEAQIMKLLRHDKLV 342
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQ 1017
+ E+ + +V E++ GSL ++L + L QL+ A Q+ EGMAY+
Sbjct 343 QLYAVVP---EEPIYIVTEFMCHGSLLEFLKDQEGQDLTLPQLVDMAAQVAEGMAYMERM 399
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
YIHRDL A N+L+ + KI DFGLA+ + + Y R+ P+ W APE +
Sbjct 400 DYIHRDLRAANILVGERLVCKIADFGLARLIEDNE--YNPRQGAKFPIKWTAPEAALFGR 457
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFG+ L EL++ + M + E +E G +P P
Sbjct 458 FTIKSDVWSFGILLTELISKGR--------------VPYPGMNNREVLEQVEHGYHMPCP 503
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
CP +Y M+ W + RPTFE L L+
Sbjct 504 PGCPASLYEAMEQTWRLDPEERPTFEYLQSFLE 536
Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 61/233 (26%), Positives = 100/233 (43%), Gaps = 19/233 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L P A E A +M + H L ++ V P I VTE++ HG L
Sbjct 310 KVAVKTLKPGTMS-PKASLEEAQIMKLLRHDKLVQLYAVVPEEPIYI-VTEFMCHGSLLE 367
Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ + G ++V +A Q+A ++Y+E + +H ++ NIL+ G K
Sbjct 368 FLKDQEGQDLTLPQLVDMAAQVAEGMAYMERMDYIHRDLRAANILV-------GERLVCK 420
Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ E + I W APE G ++ + D W FG L E+ G
Sbjct 421 IADFGLARLIEDNEYNPRQGAKFPIKWTAPEAALFGRFTIKS--DVWSFGILLTELISKG 478
Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTI 862
P + E + + +P P CP L Q +P +RP+F +
Sbjct 479 RVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYL 531
>sp|P24604|TEC_MOUSE Tyrosine-protein kinase Tec OS=Mus musculus
OX=10090 GN=Tec PE=1 SV=2
Length=630
Score = 127 bits (319), Expect = 7e-29, Method: Compositional matrix adjust.
Identities = 88/277 (32%), Positives = 134/277 (48%), Gaps = 30/277 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+R+LG G FG V L + VA+KA++ G + +E ++ L H +
Sbjct 372 MRELGSGLFGVVRLGKWRAQYK-----VAIKAIRE--GAMCEEDFIEEAKVMMKLTHPKL 424
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQ 1017
++ G C Q K + +V E++ G L ++L + ++ LL Q +CEGM YL
Sbjct 425 VQLYGVCTQQ--KPIYIVTEFMERGCLLNFLRQRQGHFSRDMLLSMCQDVCEGMEYLERN 482
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+IHRDLAARN L++ +VK+ DFG+A+ V + Y PV W PE +
Sbjct 483 SFIHRDLAARNCLVNEAGVVKVSDFGMARYVLDDQ--YTSSSGAKFPVKWCPPEVFNYSR 540
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFGV ++E+ T + P K T + ++ RG RL RP
Sbjct 541 FSSKSDVWSFGVLMWEIFTE---GRMPFEK-----------NTNYEVVTMVTRGHRLHRP 586
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+Y +M CW+ RP+ E+L L+T+ E
Sbjct 587 KLATKYLYEVMLRCWQERPEGRPSLEDL---LRTIDE 620
Score = 93.2 bits (230), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 60/222 (27%), Positives = 100/222 (45%), Gaps = 16/222 (7%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F E A +M +++H L ++GVC + +VTE++E G L +LR+ +GH + +
Sbjct 409 FIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDMLLSM 468
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
Q + + YLE + +H ++ RN L+ G+ +K+SD G+ L +
Sbjct 469 CQDVCEGMEYLERNSFIHRDLAARNCLVNEAGV-------VKVSDFGMARYVLDDQYTSS 521
Query 775 R-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
+ W PE + S+ D W FG + EI +G P + + E R
Sbjct 522 SGAKFPVKWCPPEVF--NYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTR 579
Query 830 QHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
HRL P+ + L + +C P RPS +LR + L
Sbjct 580 GHRLHRPKLATKYLYEVMLRCWQERPEGRPSLEDLLRTIDEL 621
>sp|Q19238|YS3J_CAEEL Putative tyrosine-protein kinase F09A5.2
OS=Caenorhabditis elegans OX=6239 GN=F09A5.2 PE=3 SV=3
Length=867
Score = 128 bits (322), Expect = 7e-29, Method: Compositional matrix adjust.
Identities = 88/265 (33%), Positives = 130/265 (49%), Gaps = 39/265 (15%)
Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVM 978
N+G E A+K L A Q+ + EID ++ L +H H+I GC + E +V+
Sbjct 507 NNGHYE-AAIKKLPAHADEQNHLDFFHEIDFMKRLGHHPHVISMLGCVSNPYEP--LIVV 563
Query 979 EYVPLGSLRDYLPRHS------------------IGLAQLLLFAQQICEGMAYLHAQHYI 1020
EY G L +L RH + + L+ A Q+ +GM+YL ++++I
Sbjct 564 EYCARGDLLKFLRRHKDYVLMNKTDDCPIEADMCLRIKDLVSIAWQVADGMSYLASKNFI 623
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARN+LL K+ DFGL + + + G P+ W + E LK Y+F
Sbjct 624 HRDLAARNILLTKSLTAKVSDFGLCRYMDSA---LYTAKGGRLPIKWMSVEALKLYEFST 680
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
+DVWSFGV L+E+ + D PT I Q M E L G RL +P KC
Sbjct 681 KTDVWSFGVLLFEIFSMGDVPY--PT-------IQQVDM-----LEHLLAGGRLSQPLKC 726
Query 1141 PCEVYHLMKNCWETEASFRPTFENL 1165
P E++++M+ CW + RP F +
Sbjct 727 PNEIFNIMQKCWAEKPEDRPEFNEM 751
Score = 78.6 bits (192), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 87/329 (26%), Positives = 141/329 (43%), Gaps = 55/329 (17%)
Query 575 NLSQLSFHRVDQKEI-TQLSHL-GQGTRTNVYEGRLRVEGSGDPEEGKM------DDEDP 626
N ++ +D K + Q HL G G NVY+G ++ GK+ + +
Sbjct 451 NANKKDIWEIDTKNLLVQEDHLLGNGAFANVYKGIVK---------GKIPLLVVNNSLNM 501
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHT-HLAFVHGVCVRGP-E 682
V + G + K+ P+H D L F+ M ++ H H+ + G CV P E
Sbjct 502 TVESENNGHYEAAIKKL--PAHADEQNHLDFFHEIDFMKRLGHHPHVISMLG-CVSNPYE 558
Query 683 NIMVTEYVEHGPLDVWLRRERGHV--------PMAWKMV--------VAQQLASALSYLE 726
++V EY G L +LRR + +V P+ M +A Q+A +SYL
Sbjct 559 PLIVVEYCARGDLLKFLRRHKDYVLMNKTDDCPIEADMCLRIKDLVSIAWQVADGMSYLA 618
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIP--WLAPE 782
+KN +H ++ RNILL + S K+SD G+ + + + R+P W++ E
Sbjct 619 SKNFIHRDLAARNILLTK-------SLTAKVSDFGLCRYMDSALYTAKGGRLPIKWMSVE 671
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-Q 840
L ST D W FG L EI G+ P + + RL +P CP +
Sbjct 672 ALK--LYEFSTKTDVWSFGVLLFEIFSMGDVPYPTIQQVDMLEHLLAGGRLSQPLKCPNE 729
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + +C +P RP F + ++T +
Sbjct 730 IFNIMQKCWAEKPEDRPEFNEMRGEITVM 758
>sp|P54763|EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus musculus
OX=10090 GN=Ephb2 PE=1 SV=3
Length=986
Score = 129 bits (323), Expect = 7e-29, Method: Compositional matrix adjust.
Identities = 82/273 (30%), Positives = 141/273 (52%), Gaps = 25/273 (9%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G FG+V S + P G E+ VA+K LK+ + R + E I+ H ++I
Sbjct 627 IGAGEFGEVCSGHLKLP---GKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVI 683
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018
+G + ++ E++ GSL +L ++ + QL+ + I GM YL +
Sbjct 684 HLEGVVTKS--TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMN 741
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076
Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G P+ W APE ++
Sbjct 742 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYR 801
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
KF ASDVWS+G+ ++E++++ + P MT + +E+ RLP
Sbjct 802 KFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMTNQDVINAIEQDYRLPP 847
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P CP ++ LM +CW+ + + RP F ++ L
Sbjct 848 PMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 880
Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 71/262 (27%), Positives = 125/262 (48%), Gaps = 28/262 (11%)
Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+PG+ +E+ V +K L + + F AS+M Q H ++ + GV + +++
Sbjct 642 LPGK---REIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMII 698
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TE++E+G LD +LR+ G + + + + +A+ + YL + N VH ++ RNIL+
Sbjct 699 TEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNL 758
Query 747 LAE----GTSPFIK--LSDPGV--GLGALSREERVERIP--WLAPECLPGGANSLSTAMD 796
+ + G S F++ SDP LG +IP W APE + ++A D
Sbjct 759 VCKVSDFGLSRFLEDDTSDPTYTSALGG--------KIPIRWTAPEAIQ--YRKFTSASD 808
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPT 854
W +G + E+ GE P + + + ++ +RLP P CP L L C +
Sbjct 809 VWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRN 868
Query 855 QRPSFRTILRDLTRL--QPHNL 874
RP F I+ L ++ P++L
Sbjct 869 HRPKFGQIVNTLDKMIRNPNSL 890
>sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens
OX=9606 GN=EPHB2 PE=1 SV=5
Length=1055
Score = 129 bits (323), Expect = 9e-29, Method: Compositional matrix adjust.
Identities = 82/273 (30%), Positives = 141/273 (52%), Gaps = 25/273 (9%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G FG+V S + P G E+ VA+K LK+ + R + E I+ H ++I
Sbjct 627 IGAGEFGEVCSGHLKLP---GKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVI 683
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018
+G + ++ E++ GSL +L ++ + QL+ + I GM YL +
Sbjct 684 HLEGVVTKS--TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMN 741
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076
Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G P+ W APE ++
Sbjct 742 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYR 801
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
KF ASDVWS+G+ ++E++++ + P MT + +E+ RLP
Sbjct 802 KFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMTNQDVINAIEQDYRLPP 847
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P CP ++ LM +CW+ + + RP F ++ L
Sbjct 848 PMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 880
Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 71/262 (27%), Positives = 125/262 (48%), Gaps = 28/262 (11%)
Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+PG+ +E+ V +K L + + F AS+M Q H ++ + GV + +++
Sbjct 642 LPGK---REIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMII 698
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TE++E+G LD +LR+ G + + + + +A+ + YL + N VH ++ RNIL+
Sbjct 699 TEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNL 758
Query 747 LAE----GTSPFIK--LSDPGV--GLGALSREERVERIP--WLAPECLPGGANSLSTAMD 796
+ + G S F++ SDP LG +IP W APE + ++A D
Sbjct 759 VCKVSDFGLSRFLEDDTSDPTYTSALGG--------KIPIRWTAPEAIQ--YRKFTSASD 808
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPT 854
W +G + E+ GE P + + + ++ +RLP P CP L L C +
Sbjct 809 VWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRN 868
Query 855 QRPSFRTILRDLTRL--QPHNL 874
RP F I+ L ++ P++L
Sbjct 869 HRPKFGQIVNTLDKMIRNPNSL 890
>sp|P55146|TYRO3_RAT Tyrosine-protein kinase receptor TYRO3 OS=Rattus
norvegicus OX=10116 GN=Tyro3 PE=1 SV=1
Length=880
Score = 128 bits (322), Expect = 9e-29, Method: Compositional matrix adjust.
Identities = 95/277 (34%), Positives = 132/277 (48%), Gaps = 28/277 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHI 959
R LG+G FG V DG+ VAVK LKAD + +E ++ H H+
Sbjct 512 RMLGKGEFGSVREAQLK-QEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHV 570
Query 960 IKYKGCC-EDQGEKSLQLVMEYVPL---GSLRDYLPRHSIG-------LAQLLLFAQQIC 1008
K G + + L + M +P G L +L IG L L+ F I
Sbjct 571 AKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLVRFMVDIA 630
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
GM YL ++++IHRDLAARN +L D V + DFGL++ + G +YYR PV W
Sbjct 631 CGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSG-DYYRQGCASKLPVKWL 689
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A E L + + SDVW+FGVT++E++T Q+P GI + + L
Sbjct 690 ALESLADNLYTVHSDVWAFGVTMWEIMTR---GQTP------YAGIENAE-----IYNYL 735
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
G RL +P +C EVY LM CW + RP+F L
Sbjct 736 ISGNRLKQPPECMEEVYDLMYQCWSADPKQRPSFTCL 772
Score = 78.2 bits (191), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 92/359 (26%), Positives = 159/359 (44%), Gaps = 60/359 (17%)
Query 606 GRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP---SHHDIALAFYETASL 661
GR+ +G G E ++ ED G ++V +K+L + DI F A+
Sbjct 511 GRMLGKGEFGSVREAQLKQED--------GSFVKVAVKMLKADIIASSDIE-EFLREAAC 561
Query 662 MSQVSHTHLAFVHGVCVRG------PENIMVTEYVEHGPLDVWLRRER-----GHVPMAW 710
M + H H+A + GV +R P +++ +++HG L +L R ++P+
Sbjct 562 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQT 621
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGA 766
+ +A + YL ++N +H ++ RN +LA + ++D G+ G
Sbjct 622 LVRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE-------DMTVCVADFGLSRKIYSGD 674
Query 767 LSREERVERIP--WLAPECLPGGANSLSTA-MDKWGFGATLLEICFDGEAPLQSRSPSEK 823
R+ ++P WLA E L A++L T D W FG T+ EI G+ P +E
Sbjct 675 YYRQGCASKLPVKWLALESL---ADNLYTVHSDVWAFGVTMWEIMTRGQTPYAGIENAEI 731
Query 824 EHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
++ +RL +P ++ L QC + +P QRPSF + R++ N+ L+V
Sbjct 732 YNYLISGNRLKQPPECMEEVYDLMYQCWSADPKQRPSFTCL-----RMELENILGHLSVL 786
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN----DGTGEMVAVKALKADC 936
S + DP Y+ R G L C + ++ DG+G M A+ + +DC
Sbjct 787 --STSQDPL-----YINIERAGQPAENGSPELPCGEQSSSEAGDGSG-MGAIGGIPSDC 837
>sp|Q13882|PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo sapiens
OX=9606 GN=PTK6 PE=1 SV=1
Length=451
Score = 124 bits (312), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 89/268 (33%), Positives = 135/268 (50%), Gaps = 28/268 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LG G+FG+V + VA+K + D H+ + EI ++ L H+HI+
Sbjct 195 RKLGSGYFGEVFEGLWKDRVQ-----VAIKVISRD-NLLHQQMLQSEIQAMKKLRHKHIL 248
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ ++ E + GSL + L + +++LL A Q+ EGM YL +Q
Sbjct 249 ALYAVV--SVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQ 306
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+YIHRDLAARN+L+ + L K+GDFGLA+ + E + D + P W APE L
Sbjct 307 NYIHRDLAARNILVGENTLCKVGDFGLARLIKED---VYLSHDHNIPYKWTAPEALSRGH 363
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ SDVWSFG+ L+E+ + Q P G++ + LR ++ G R+P P
Sbjct 364 YSTKSDVWSFGILLHEMFSR---GQVP------YPGMSNHE-AFLR----VDAGYRMPCP 409
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165
+CP V+ LM CW + RP F+ L
Sbjct 410 LECPPSVHKLMLTCWCRDPEQRPCFKAL 437
Score = 78.2 bits (191), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 65/220 (30%), Positives = 99/220 (45%), Gaps = 20/220 (9%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV-PMAWKMVVAQQLAS 720
M ++ H H+ ++ V G ++TE + G L LR V P++ + +A Q+A
Sbjct 239 MKKLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAE 298
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV----ERI 776
+ YLE++N +H ++ RNIL+ G + K+ D GL L +E+ I
Sbjct 299 GMCYLESQNYIHRDLAARNILV-------GENTLCKVGD--FGLARLIKEDVYLSHDHNI 349
Query 777 P--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834
P W APE L G ST D W FG L E+ G+ P S E +R+P
Sbjct 350 PYKWTAPEALSRG--HYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMP 407
Query 835 EP-SC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
P C P + L C +P QRP F+ + L+ +
Sbjct 408 CPLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFTSY 447
>sp|P28693|EPHB2_CHICK Ephrin type-B receptor 2 OS=Gallus gallus
OX=9031 GN=EPHB2 PE=1 SV=3
Length=1004
Score = 128 bits (321), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 82/273 (30%), Positives = 141/273 (52%), Gaps = 25/273 (9%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G FG+V S + P G E+ VA+K LK+ + R + E I+ H ++I
Sbjct 645 IGAGEFGEVCSGHLKLP---GKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVI 701
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018
+G + ++ E++ GSL +L ++ + QL+ + I GM YL +
Sbjct 702 HLEGVVTK--SSPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMN 759
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076
Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G P+ W APE ++
Sbjct 760 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYR 819
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
KF ASDVWS+G+ ++E++++ + P MT + +E+ RLP
Sbjct 820 KFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMTNQDVINAIEQDYRLPP 865
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P CP ++ LM +CW+ + + RP F ++ L
Sbjct 866 PMDCPNALHQLMLDCWQKDRNHRPKFGQIVNTL 898
Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 71/262 (27%), Positives = 125/262 (48%), Gaps = 28/262 (11%)
Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+PG+ +E+ V +K L + + F AS+M Q H ++ + GV + +++
Sbjct 660 LPGK---REIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMII 716
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TE++E+G LD +LR+ G + + + + +A+ + YL + N VH ++ RNIL+
Sbjct 717 TEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNL 776
Query 747 LAE----GTSPFIK--LSDPGV--GLGALSREERVERIP--WLAPECLPGGANSLSTAMD 796
+ + G S F++ SDP LG +IP W APE + ++A D
Sbjct 777 VCKVSDFGLSRFLEDDTSDPTYTSALGG--------KIPIRWTAPEAIQ--YRKFTSASD 826
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPT 854
W +G + E+ GE P + + + ++ +RLP P CP L L C +
Sbjct 827 VWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPNALHQLMLDCWQKDRN 886
Query 855 QRPSFRTILRDLTRL--QPHNL 874
RP F I+ L ++ P++L
Sbjct 887 HRPKFGQIVNTLDKMIRNPNSL 908
>sp|P29376|LTK_HUMAN Leukocyte tyrosine kinase receptor OS=Homo
sapiens OX=9606 GN=LTK PE=1 SV=3
Length=864
Score = 127 bits (320), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 94/300 (31%), Positives = 140/300 (47%), Gaps = 38/300 (13%)
Query 900 IRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+R LG G FG+V L P D + VA+K L C PQ + E I+ H+
Sbjct 513 LRALGHGAFGEVYEGLVIGLP-GDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQ 571
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------IGLAQLLLFAQQIC 1008
+I++ G + +++E + G ++ +L RHS + + LL AQ I
Sbjct 572 NIVRCVGLSLRATPR--LILLELMSGGDMKSFL-RHSRPHLGQPSPLVMRDLLQLAQDIA 628
Query 1009 EGMAYLHAQHYIHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
+G YL H+IHRD+AARN LL R+ KIGDFG+A+ + YYR + PV
Sbjct 629 QGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRA-SYYRRGDRALLPV 687
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
W PE E F +D WSFGV L+E+ + ++ G T +
Sbjct 688 KWMPPEAFLEGIFTSKTDSWSFGVLLWEIFS---------LGYMPYPG-----RTNQEVL 733
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
+ + G R+ P CP VY +M CW+ E RP+F +++ L +Y Q P V +
Sbjct 734 DFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERL-----QYCTQDPDVLN 788
Score = 80.9 bits (198), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 83/299 (28%), Positives = 124/299 (41%), Gaps = 42/299 (14%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +T L LG G VYEG + G D PL +V +K
Sbjct 505 VSPANVTLLRALGHGAFGEVYEGLVI---------GLPGDSSPL----------QVAIKT 545
Query 644 LDP--SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
L S D L F A ++S+ H ++ G+ +R +++ E + G + +LR
Sbjct 546 LPELCSPQD-ELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRH 604
Query 702 ERGHVPMAWKMV------VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
R H+ +V +AQ +A YLE + +H ++ RN LL+ G S
Sbjct 605 SRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLS----CAGPSRVA 660
Query 756 KLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
K+ D G+ + S R +R + W+ PE G ++ D W FG L EI
Sbjct 661 KIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGI--FTSKTDSWSFGVLLWEIFS 718
Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDL 866
G P R+ E F R+ P CP + + +QC +EP RPSF +IL L
Sbjct 719 LGYMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERL 777
>sp|Q8JH64|BTK_CHICK Tyrosine-protein kinase BTK OS=Gallus gallus
OX=9031 GN=BTK PE=1 SV=1
Length=657
Score = 126 bits (317), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 83/269 (31%), Positives = 133/269 (49%), Gaps = 27/269 (10%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+++LG G FG V + + VA+K ++ G + E ++ L HE +
Sbjct 403 LKELGTGQFGVVKYGKWRGQYN-----VAIKMIRE--GSMSEDEFIDEAKVMMNLSHEKL 455
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
++ G C Q + + ++ EY+ G L ++L + A+LL + +CE M YL ++
Sbjct 456 VQLYGVCTKQ--RPIFIITEYMANGCLLNFLRETQRRFQPAELLEMCKDVCEAMEYLESK 513
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
++HRDLAARN L+++ +VK+ DFGL++ V + Y PV W PE L K
Sbjct 514 QFLHRDLAARNCLVNDQGIVKVSDFGLSRYVLDDE--YTSSMGSKFPVRWSPPEVLLYSK 571
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFGV ++E+ + L + + TE + +G RL RP
Sbjct 572 FSSKSDVWSFGVLMWEVYS--------------LGKMPYERFNNSETTEHVIQGLRLYRP 617
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ VY +M +CW +A RPTF L+
Sbjct 618 QQASERVYAIMYSCWHEKAEERPTFSALL 646
Score = 79.7 bits (195), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 79/323 (24%), Positives = 140/323 (43%), Gaps = 54/323 (17%)
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE---EG 619
+ R +++P T L S+ +D K++T L LG G V G+ R + + + EG
Sbjct 375 VSRHQKSAPSTAGLGYGSWE-IDPKDLTFLKELGTGQFGVVKYGKWRGQYNVAIKMIREG 433
Query 620 KMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR 679
M +++ F + A +M +SH L ++GVC +
Sbjct 434 SMSEDE-----------------------------FIDEAKVMMNLSHEKLVQLYGVCTK 464
Query 680 GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRN 739
++TEY+ +G L +LR + A + + + + A+ YLE+K +H ++ RN
Sbjct 465 QRPIFIITEYMANGCLLNFLRETQRRFQPAELLEMCKDVCEAMEYLESKQFLHRDLAARN 524
Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTA 794
L+ G+ +K+SD G+ L E + W PE L + S+
Sbjct 525 CLVNDQGI-------VKVSDFGLSRYVLDDEYTSSMGSKFPVRWSPPEVLL--YSKFSSK 575
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSE-KEHFYQ--RQHRLPEPSCPQLATLTSQCLTY 851
D W FG + E+ G+ P + + SE EH Q R +R P+ + ++ + C
Sbjct 576 SDVWSFGVLMWEVYSLGKMPYERFNNSETTEHVIQGLRLYR-PQQASERVYAIMYSCWHE 634
Query 852 EPTQRPSFRTIL---RDLTRLQP 871
+ +RP+F +L D+T +P
Sbjct 635 KAEERPTFSALLGSIVDITDEEP 657
>sp|Q62413|EPHA6_MOUSE Ephrin type-A receptor 6 OS=Mus musculus
OX=10090 GN=Epha6 PE=1 SV=2
Length=1035
Score = 128 bits (321), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 94/342 (27%), Positives = 158/342 (46%), Gaps = 70/342 (20%)
Query 880 VNPDSPASDPTVFHKRYLKKI--------RDLGEGHFGKVSLYCYDPTND-GTGEM-VAV 929
++PD+ DP++ + K+I R +G G FG+V C G E+ VA+
Sbjct 606 IDPDT-YEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEV---CSGRLKTPGKREIPVAI 661
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ-------------------- 969
K LK + R + +E I+ H +II+ +G +
Sbjct 662 KTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFL 721
Query 970 --------------------GEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQI 1007
+ + +V+EY+ GSL +L +H + QL+ + I
Sbjct 722 NGIQAPHPVTAGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGI 781
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
GM YL Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W
Sbjct 782 ASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRW 841
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + KF ASD WS+G+ ++E++++ + P + E+ Q +L
Sbjct 842 TAPEAIAYRKFSSASDAWSYGIVMWEVMSY---GERP---YWEM----SNQDVILS---- 887
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+E G RLP P CP ++ LM +CW+ E + RP F +++ L
Sbjct 888 IEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFL 929
Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 87/341 (26%), Positives = 134/341 (39%), Gaps = 70/341 (21%)
Query 607 RLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQ 664
R+R+E G E G++ PG+ +E+ V +K L H D F AS+M Q
Sbjct 629 RIRIERVIGAGEFGEVCSGRLKTPGK---REIPVAIKTLKGGHMDRQRRDFLREASIMGQ 685
Query 665 VSHTHLAFVHGVCVR------------------------------------------GPE 682
H ++ + GV + G
Sbjct 686 FDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNGIQAPHPVTAGGSLPPRIPAGRP 745
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
++V EY+E+G LD +LR+ GH + + + + +AS + YL + VH ++ RNIL+
Sbjct 746 VMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILV 805
Query 743 ARLGLAEGTSPFIKLSDPGVGL-------GALSREERVERIPWLAPECLPGGANSLSTAM 795
++ K+SD G+ A + I W APE + S+A
Sbjct 806 -------NSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAI--AYRKFSSAS 856
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEP 853
D W +G + E+ GE P S + + +RLP P C P L L C E
Sbjct 857 DAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKER 916
Query 854 TQRPSFRTILRDLTRL-----QPHNLADVLTVNPDSPASDP 889
RP F I+ L +L H L + + V P+SP P
Sbjct 917 NHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGDVP 957
>sp|P55144|TYRO3_MOUSE Tyrosine-protein kinase receptor TYRO3
OS=Mus musculus OX=10090 GN=Tyro3 PE=1 SV=2
Length=880
Score = 127 bits (319), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 95/277 (34%), Positives = 132/277 (48%), Gaps = 28/277 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHI 959
R LG+G FG V DG+ VAVK LKAD + +E ++ H H+
Sbjct 512 RMLGKGEFGSVREAQLK-QEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHV 570
Query 960 IKYKGCC-EDQGEKSLQLVMEYVPL---GSLRDYLPRHSIG-------LAQLLLFAQQIC 1008
K G + + L + M +P G L +L IG L L+ F I
Sbjct 571 AKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLVRFMVDIA 630
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
GM YL ++++IHRDLAARN +L D V + DFGL++ + G +YYR PV W
Sbjct 631 CGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSG-DYYRQGCASKLPVKWL 689
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A E L + + SDVW+FGVT++E++T Q+P GI + + L
Sbjct 690 ALESLADNLYTVHSDVWAFGVTMWEIMTR---GQTP------YAGIENAE-----IYNYL 735
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
G RL +P +C EVY LM CW + RP+F L
Sbjct 736 IGGNRLKQPPECMEEVYDLMYQCWSADPKQRPSFTCL 772
Score = 74.7 bits (182), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 78/302 (26%), Positives = 136/302 (45%), Gaps = 45/302 (15%)
Query 606 GRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP---SHHDIALAFYETASL 661
GR+ +G G E ++ ED G ++V +K+L + DI F A+
Sbjct 511 GRMLGKGEFGSVREAQLKQED--------GSFVKVAVKMLKADIIASSDIE-EFLREAAC 561
Query 662 MSQVSHTHLAFVHGVCVRG------PENIMVTEYVEHGPLDVWLRRER-----GHVPMAW 710
M + H H+A + GV +R P +++ +++HG L +L R ++P+
Sbjct 562 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQT 621
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGA 766
+ +A + YL ++N +H ++ RN +LA + ++D G+ G
Sbjct 622 LVRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE-------DMTVCVADFGLSRKIYSGD 674
Query 767 LSREERVERIP--WLAPECLPGGANSLSTA-MDKWGFGATLLEICFDGEAPLQSRSPSEK 823
R+ ++P WLA E L A++L T D W FG T+ EI G+ P +E
Sbjct 675 YYRQGCASKLPVKWLALESL---ADNLYTVHSDVWAFGVTMWEIMTRGQTPYAGIENAEI 731
Query 824 EHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
++ +RL +P ++ L QC + +P QRPSF + +L + H VL+ +
Sbjct 732 YNYLIGGNRLKQPPECMEEVYDLMYQCWSADPKQRPSFTCLRMELENILGH--LSVLSTS 789
Query 882 PD 883
D
Sbjct 790 QD 791
>sp|D2IYS2|TORSO_BOMMO Tyrosine-protein kinase receptor torso
OS=Bombyx mori OX=7091 GN=tor PE=1 SV=1
Length=807
Score = 127 bits (319), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 93/312 (30%), Positives = 138/312 (44%), Gaps = 71/312 (23%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961
+GEG FG V P G+ VAVK LK + ++ E+++++++ H H++
Sbjct 445 IGEGAFGVVRRGTLAPG----GKSVAVKMLKEFPSQEEVRSFRSEMELMKSVGAHPHVVS 500
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--------PRHSIGLAQ-------------- 999
GCC G K L +V EY G L YL +H+
Sbjct 501 LVGCC--SGRKPL-IVAEYCSRGDLLSYLRSSWDIIVSKHTAKYYNNNMDSMDTSKLKVH 557
Query 1000 --------------------------LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033
LL F +QI GM +L + +HRDLAARNVL+
Sbjct 558 KEHTKLVVNKLYELQGPCETELTPLDLLSFCRQIAMGMEFLASNRIVHRDLAARNVLVTE 617
Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
D+ +KI DFGL++ + E ++ Y+ + +G PV W A E L + SDVWSFGV ++E
Sbjct 618 DKTLKIADFGLSRDIYEENQ-YKQKGNGKMPVKWMALESLTRRVYTTQSDVWSFGVVIWE 676
Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
++T + G ++ RL L G R+P+P C +Y +M+ CW
Sbjct 677 IVT--------------VGGSPYPEVPAARLVRSLRSGYRMPKPVNCSKPLYDIMRACWN 722
Query 1154 TEASFRPTFENL 1165
RPTF L
Sbjct 723 ASPRDRPTFPEL 734
Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 46/196 (23%), Positives = 82/196 (42%), Gaps = 22/196 (11%)
Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER 775
+Q+A + +L + +VH ++ RN+L+ +K++D G+ + ++
Sbjct 589 RQIAMGMEFLASNRIVHRDLAARNVLVTE-------DKTLKIADFGLSRDIYEENQYKQK 641
Query 776 ------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
+ W+A E L +T D W FG + EI G +P + +
Sbjct 642 GNGKMPVKWMALESL--TRRVYTTQSDVWSFGVVIWEIVTVGGSPYPEVPAARLVRSLRS 699
Query 830 QHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI---LRDLTRLQPHNLADVLTVNPDS 884
+R+P+P +C + L + C P RP+F + L DL N L V+ D
Sbjct 700 GYRMPKPVNCSKPLYDIMRACWNASPRDRPTFPELHQKLDDLLHSACANEYITLEVDVDE 759
Query 885 PASDPTVFHKRYLKKI 900
S P +RY+K +
Sbjct 760 APSTPK--PQRYIKML 773
>sp|P16879|FES_MOUSE Tyrosine-protein kinase Fes/Fps OS=Mus musculus
OX=10090 GN=Fes PE=1 SV=2
Length=822
Score = 127 bits (318), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 87/277 (31%), Positives = 137/277 (49%), Gaps = 23/277 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G+FG+V + D T VAVK+ + P ++ + QE IL+ H +I++
Sbjct 567 IGRGNFGEV--FSGRLRADNTP--VAVKSCRETLPPDLKAKFLQEARILKQYNHPNIVRL 622
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C + + + +VME V G +L + + LL GM YL ++ I
Sbjct 623 IGVCTQK--QPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCI 680
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARN L+ ++KI DFG+++ +G Y PV W APE L ++
Sbjct 681 HRDLAARNCLVTEKNVLKISDFGMSREEADGI-YAASAGLRQVPVKWTAPEALNYGRYSS 739
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWSFG+ L+E + +S P +T + E +E+G RLP P+ C
Sbjct 740 ESDVWSFGILLWETFS-LGASPYP-------------NLTNQQTREFVEKGHRLPCPELC 785
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
P V+ LM+ CW E RP+F + L ++ ++++
Sbjct 786 PDAVFRLMEQCWAYEPGQRPSFSIICQELHSIRKRHR 822
Score = 98.6 bits (244), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 79/281 (28%), Positives = 125/281 (44%), Gaps = 40/281 (14%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
+G+G V+ GRLR D P+ ++ + L P D+
Sbjct 566 QIGRGNFGEVFSGRLRA------------DNTPVA--------VKSCRETLPP---DLKA 602
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F + A ++ Q +H ++ + GVC + +V E V+ G +LR E + + +
Sbjct 603 KFLQEARILKQYNHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQ 662
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGAL 767
+ A+ + YLE+K +H ++ RN L+ + +K+SD G+ G+ A
Sbjct 663 MVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNV-------LKISDFGMSREEADGIYAA 715
Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
S R + W APE L G S+ D W FG L E G +P + + + F
Sbjct 716 SAGLRQVPVKWTAPEALNYG--RYSSESDVWSFGILLWETFSLGASPYPNLTNQQTREFV 773
Query 828 QRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866
++ HRLP P CP + L QC YEP QRPSF I ++L
Sbjct 774 EKGHRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSIICQEL 814
>sp|P08941|ROS1_CHICK Proto-oncogene tyrosine-protein kinase ROS
OS=Gallus gallus OX=9031 GN=ROS1 PE=1 SV=3
Length=2311
Score = 128 bits (321), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 96/278 (35%), Positives = 134/278 (48%), Gaps = 37/278 (13%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG G FG+V D DG+GE VAVK LK Q +S + +E ++ H HI+
Sbjct 1967 LGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMSKFDHPHIL 2026
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQLLLFAQQICEG 1010
K G C + L++E + G L YL P ++ + IC+G
Sbjct 2027 KLLGVCLLNEPQ--YLILELMEGGDLLSYLRGARKQKFQSPLLTLTDLLDICL--DICKG 2082
Query 1011 MAYLHAQHYIHRDLAARNVLLDN------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
YL +IHRDLAARN L+ R+VKIGDFGLA+ + + ++YYR R +G
Sbjct 2083 CVYLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYK-NDYYRKRGEGLIN 2141
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
V W APE L + F SDVW+FGV ++E LT Q P ++ + +
Sbjct 2142 VRWMAPESLIDGVFTNHSDVWAFGVLVWETLTL---GQQP-----------YPGLSNIEV 2187
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
+ G RL P+ CP ++ LM CW + RPTF
Sbjct 2188 LHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTF 2225
Score = 73.6 bits (179), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 75/294 (26%), Positives = 116/294 (39%), Gaps = 42/294 (14%)
Query 595 LGQGTRTNVYEGR---LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651
LG G VYEG + +GSG E RV +K L D
Sbjct 1967 LGSGAFGEVYEGTALDILADGSG---------------------ESRVAVKTLKRGATDQ 2005
Query 652 ALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH----- 705
+ F + A LMS+ H H+ + GVC+ ++ E +E G L +LR R
Sbjct 2006 EKSEFLKEAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRGARKQKFQSP 2065
Query 706 -VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + + + + YLE +H ++ RN L++ S +K+ D G+
Sbjct 2066 LLTLTDLLDICLDICKGCVYLEKMRFIHRDLAARNCLVSEKQYG-SCSRVVKIGDFGLAR 2124
Query 765 GAL------SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
R E + + W+APE L G + D W FG + E G+ P
Sbjct 2125 DIYKNDYYRKRGEGLINVRWMAPESLIDGV--FTNHSDVWAFGVLVWETLTLGQQPYPGL 2182
Query 819 SPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
S E H + RL P +CP + L ++C +P RP+F I L ++
Sbjct 2183 SNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEIR 2236
>sp|Q06418|TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3
OS=Homo sapiens OX=9606 GN=TYRO3 PE=1 SV=1
Length=890
Score = 127 bits (319), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 94/277 (34%), Positives = 132/277 (48%), Gaps = 28/277 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHI 959
R LG+G FG V DG+ VAVK LKAD + +E ++ H H+
Sbjct 522 RMLGKGEFGSVREAQLK-QEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHV 580
Query 960 IKYKGCC-EDQGEKSLQLVMEYVPL---GSLRDYLPRHSIG-------LAQLLLFAQQIC 1008
K G + + L + M +P G L +L IG L L+ F I
Sbjct 581 AKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLIRFMVDIA 640
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
GM YL ++++IHRDLAARN +L D V + DFGL++ + G +YYR PV W
Sbjct 641 CGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSG-DYYRQGCASKLPVKWL 699
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
A E L + + SDVW+FGVT++E++T Q+P GI + + L
Sbjct 700 ALESLADNLYTVQSDVWAFGVTMWEIMTR---GQTP------YAGIENAE-----IYNYL 745
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
G RL +P +C +VY LM CW + RP+F L
Sbjct 746 IGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCL 782
Score = 76.6 bits (187), Expect = 9e-13, Method: Compositional matrix adjust.
Identities = 91/357 (25%), Positives = 153/357 (43%), Gaps = 56/357 (16%)
Query 606 GRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP---SHHDIALAFYETASL 661
GR+ +G G E ++ ED G ++V +K+L + DI F A+
Sbjct 521 GRMLGKGEFGSVREAQLKQED--------GSFVKVAVKMLKADIIASSDIE-EFLREAAC 571
Query 662 MSQVSHTHLAFVHGVCVRG------PENIMVTEYVEHGPLDVWLRRER-----GHVPMAW 710
M + H H+A + GV +R P +++ +++HG L +L R ++P+
Sbjct 572 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQT 631
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGA 766
+ +A + YL ++N +H ++ RN +LA + ++D G+ G
Sbjct 632 LIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE-------DMTVCVADFGLSRKIYSGD 684
Query 767 LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
R+ ++P WLA E L N + D W FG T+ EI G+ P +E
Sbjct 685 YYRQGCASKLPVKWLALESL--ADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIY 742
Query 825 HFYQRQHRLPE-PSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
++ +RL + P C + + L QC + +P QRPSF + R++ N+ L+V
Sbjct 743 NYLIGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCL-----RMELENILGQLSVL- 796
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE---MVAVKALKADC 936
S + DP Y+ R G + L D G G+ M AV +DC
Sbjct 797 -SASQDPL-----YINIERAEEPTAGGSLELPGRDQPYSGAGDGSGMGAVGGTPSDC 847
>sp|Q90344|EPHB2_COTJA Ephrin type-B receptor 2 OS=Coturnix japonica
OX=93934 GN=EPHB2 PE=2 SV=1
Length=987
Score = 127 bits (319), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 82/273 (30%), Positives = 140/273 (51%), Gaps = 25/273 (9%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G FG+V S + P G E+ VA+K LK+ + R + E I+ H ++I
Sbjct 628 IGAGEFGEVCSGHLKLP---GKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVI 684
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018
+G + ++ E++ GSL +L ++ + QL+ + I GM YL +
Sbjct 685 HLEGVVTK--SSPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMN 742
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076
Y+HRDLAARN L++++ + K+ DFGL++ + + Y G P+ W APE ++
Sbjct 743 YVHRDLAARNTLVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYR 802
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
KF ASDVWS+G+ ++E++++ + P MT + +E+ RLP
Sbjct 803 KFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMTNQDVINAIEQDYRLPP 848
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P CP ++ LM +CW+ + + RP F ++ L
Sbjct 849 PMDCPNALHQLMLDCWQKDRNHRPKFGQIVNTL 881
Score = 87.0 bits (214), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 70/262 (27%), Positives = 124/262 (47%), Gaps = 28/262 (11%)
Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+PG+ +E+ V +K L + + F AS+M Q H ++ + GV + +++
Sbjct 643 LPGK---REIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMII 699
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TE++E+G LD +LR+ G + + + + +A+ + YL + N VH ++ RN L+
Sbjct 700 TEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNTLVNSNL 759
Query 747 LAE----GTSPFIK--LSDPGV--GLGALSREERVERIP--WLAPECLPGGANSLSTAMD 796
+ + G S F++ SDP LG +IP W APE + ++A D
Sbjct 760 VCKVSDFGLSRFLEDDTSDPTYTSALGG--------KIPIRWTAPEAIQ--YRKFTSASD 809
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPT 854
W +G + E+ GE P + + + ++ +RLP P CP L L C +
Sbjct 810 VWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPNALHQLMLDCWQKDRN 869
Query 855 QRPSFRTILRDLTRL--QPHNL 874
RP F I+ L ++ P++L
Sbjct 870 HRPKFGQIVNTLDKMIRNPNSL 891
>sp|Q54TM7|DRKD_DICDI Probable serine/threonine-protein kinase
drkD OS=Dictyostelium discoideum OX=44689 GN=drkD PE=2 SV=1
Length=1288
Score = 127 bits (319), Expect = 3e-28, Method: Compositional matrix adjust.
Identities = 96/285 (34%), Positives = 144/285 (51%), Gaps = 39/285 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G +G+V + G VAVK L D + S ++E+D+L L H +I+
Sbjct 857 IGRGGYGQVFRGSW------RGTEVAVKMLFNDNVNLKLISDLRKEVDLLCKLRHPNIVL 910
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI----GLAQLLLFAQQICEGMAYLHAQ 1017
+ G C + S +V EY+ GSL + L SI GL L F GM YLH++
Sbjct 911 FMGACTEPS--SPCIVTEYLSRGSLANILLDESIEMDWGLRLQLGF--DCARGMTYLHSR 966
Query 1018 H--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ IHRDL N+L+D+ VK+ DFGLA + H + + W APE L E
Sbjct 967 NPIIIHRDLKTDNLLVDDSWQVKVADFGLATV--KSHTFAKTM---CGTTGWVAPEVLAE 1021
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA-QGQMTVLRLTELLERGERL 1134
+ +DV+S+ + L+ELLT LI A + M V+R ++RGERL
Sbjct 1022 EGYTEKADVYSYAIVLWELLTR-------------LIPYAGKNTMQVVRS---IDRGERL 1065
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
P P CP + LM CWET+ + RP+F ++PI++ + ++Q +
Sbjct 1066 PMPAWCPPKYAALMNRCWETDPTHRPSFPEILPIMEGMISEFQKE 1110
Score = 55.1 bits (131), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 56/239 (23%), Positives = 101/239 (42%), Gaps = 20/239 (8%)
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
RG E+ V + D + + + L+ ++ H ++ G C +VTEY+
Sbjct 871 RGTEVAVKMLFNDNVNLKLISDLRKEVDLLCKLRHPNIVLFMGACTEPSSPCIVTEYLSR 930
Query 693 GPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEG 750
G L L E + ++ + A ++YL ++N ++H ++ N+L+
Sbjct 931 GSLANILLDESIEMDWGLRLQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLV-------D 983
Query 751 TSPFIKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLE 806
S +K++D GL + + + W+APE L + D + + L E
Sbjct 984 DSWQVKVAD--FGLATVKSHTFAKTMCGTTGWVAPEVL--AEEGYTEKADVYSYAIVLWE 1039
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-C-PQLATLTSQCLTYEPTQRPSFRTIL 863
+ P ++ + R RLP P+ C P+ A L ++C +PT RPSF IL
Sbjct 1040 L-LTRLIPYAGKNTMQVVRSIDRGERLPMPAWCPPKYAALMNRCWETDPTHRPSFPEIL 1097
>sp|Q8QFP9|TYRO3_XENLA Tyrosine-protein kinase receptor TYRO3
OS=Xenopus laevis OX=8355 GN=tyro3 PE=1 SV=1
Length=880
Score = 126 bits (317), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 93/285 (33%), Positives = 136/285 (48%), Gaps = 30/285 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEH 958
R LG+G FG V D T + VAVK LKA+ C + +E ++ H +
Sbjct 507 RTLGKGEFGSVR-EAQLKMEDDTMQKVAVKMLKAEIFCSSDIEE-FLREAAFMKEFDHPN 564
Query 959 IIKYKGCCEDQGEKSL----QLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFAQQI 1007
+ K G K +++ ++ G L +L IG + L+ F I
Sbjct 565 VCKLIGVSLRSRTKGRLPVPMVILPFMKHGDLHTFLLMSRIGEEPITLPVQTLVRFMIDI 624
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
C GM YL ++++IHRDLA RN +L+ D V + DFGL+K + G +YYR PV W
Sbjct 625 CSGMEYLSSKNFIHRDLATRNCMLNEDMTVCVADFGLSKKIYSG-DYYRQGCASKLPVKW 683
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
A E L + + SDVW+FGVTL+E+ T Q+P G+ + +
Sbjct 684 LALESLADNVYTVHSDVWAFGVTLWEIATL---GQTP------YAGVENSE-----IYSY 729
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
L G RL +P C E+Y +M CW TE RP+F +L L+ +
Sbjct 730 LIAGNRLKQPLDCLDELYEMMCQCWITEPKRRPSFVDLKQRLEAI 774
Score = 70.1 bits (170), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 79/303 (26%), Positives = 128/303 (42%), Gaps = 49/303 (16%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S+L + Q++ T LG+G +V E +L KM+D D Q+
Sbjct 491 SKLKDVLIQQQQFTLGRTLGKGEFGSVREAQL-----------KMED--------DTMQK 531
Query 637 LRV-VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEY 689
+ V +LK DI F A+ M + H ++ + GV +R P +++ +
Sbjct 532 VAVKMLKAEIFCSSDIE-EFLREAAFMKEFDHPNVCKLIGVSLRSRTKGRLPVPMVILPF 590
Query 690 VEHGPLDVWLRRER-GHVPMAWKMVVAQQ----LASALSYLENKNLVHGNVCGRNILLAR 744
++HG L +L R G P+ + + + S + YL +KN +H ++ RN +L
Sbjct 591 MKHGDLHTFLLMSRIGEEPITLPVQTLVRFMIDICSGMEYLSSKNFIHRDLATRNCMLNE 650
Query 745 LGLAEGTSPFIKLSDPGVGL----GALSREERVERIP--WLAPECLPGGANSLSTAMDKW 798
+ ++D G+ G R+ ++P WLA E L N + D W
Sbjct 651 -------DMTVCVADFGLSKKIYSGDYYRQGCASKLPVKWLALESL--ADNVYTVHSDVW 701
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQR 856
FG TL EI G+ P SE + +RL +P +L + QC EP +R
Sbjct 702 AFGVTLWEIATLGQTPYAGVENSEIYSYLIAGNRLKQPLDCLDELYEMMCQCWITEPKRR 761
Query 857 PSF 859
PSF
Sbjct 762 PSF 764
>sp|Q03526|ITK_MOUSE Tyrosine-protein kinase ITK/TSK OS=Mus musculus
OX=10090 GN=Itk PE=1 SV=1
Length=625
Score = 125 bits (313), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 83/280 (30%), Positives = 131/280 (47%), Gaps = 27/280 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L ++++G G FG V L + + VA+K ++ G + +E +++ L H
Sbjct 368 LTFVQEIGSGQFGLVHLGYW-----LNKDKVAIKTIQE--GAMSEEDFIEEAEVMMKLSH 420
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYL 1014
+++ G C +Q + LV E++ G L DYL R LL +CEGMAYL
Sbjct 421 PKLVQLYGVCLEQA--PICLVFEFMEHGCLSDYLRSQRGLFAAETLLGMCLDVCEGMAYL 478
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDLAARN L+ ++++K+ DFG+ + V + Y PV W +PE
Sbjct 479 EKACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQ--YTSSTGTKFPVKWASPEVFS 536
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
++ SDVWSFGV ++E+ + I + + E + G RL
Sbjct 537 FSRYSSKSDVWSFGVLMWEVFSEGK--------------IPYENRSNSEVVEDISTGFRL 582
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+P C VY +M +CW+ + RP F L+ L + E
Sbjct 583 YKPRLASCHVYQIMNHCWKEKPEDRPPFSQLLSQLAEIAE 622
Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 61/223 (27%), Positives = 103/223 (46%), Gaps = 18/223 (8%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F E A +M ++SH L ++GVC+ +V E++EHG L +LR +RG + +
Sbjct 408 FIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRSQRGLFAAETLLGM 467
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ ++YLE ++H ++ RN L+ G + IK+SD G+ L +
Sbjct 468 CLDVCEGMAYLEKACVIHRDLAARNCLV-------GENQVIKVSDFGMTRFVLDDQYTSS 520
Query 775 R-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
+ W +PE + S+ D W FG + E+ +G+ P ++RS SE
Sbjct 521 TGTKFPVKWASPEVF--SFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDIST 578
Query 830 QHRLPEP---SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
RL +P SC + + + C +P RP F +L L +
Sbjct 579 GFRLYKPRLASC-HVYQIMNHCWKEKPEDRPPFSQLLSQLAEI 620
>sp|P18475|TORSO_DROME Tyrosine-protein kinase receptor torso
OS=Drosophila melanogaster OX=7227 GN=tor PE=1 SV=2
Length=923
Score = 126 bits (317), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 73/187 (39%), Positives = 98/187 (52%), Gaps = 14/187 (7%)
Query 979 EYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
EY D PR + A LL AQQ+ GM +L +HRDLAARNVL+ DR +K
Sbjct 697 EYFDCLDSSDTKPRIPLKYADLLDIAQQVAVGMEFLAQNKVVHRDLAARNVLISVDRSIK 756
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
I DFGL++ V + Y + G P+ W A E L + SDVWSFGV LYE+ T
Sbjct 757 IADFGLSRDVYHENVYRKSGGSGKLPIKWLALESLTHQVYTSQSDVWSFGVLLYEITT-- 814
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
L G+ ++ L +LL +G R+ RP+ C E++ LM++CW + S
Sbjct 815 ------------LGGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQEMFSLMESCWSSVPSH 862
Query 1159 RPTFENL 1165
RPTF L
Sbjct 863 RPTFSAL 869
Score = 63.9 bits (154), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 53/186 (28%), Positives = 81/186 (44%), Gaps = 36/186 (19%)
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE--- 770
+AQQ+A + +L +VH ++ RN+L++ IK++D G LSR+
Sbjct 721 IAQQVAVGMEFLAQNKVVHRDLAARNVLIS-------VDRSIKIADFG-----LSRDVYH 768
Query 771 ERVER---------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
E V R I WLA E L ++ D W FG L EI G P S SPS
Sbjct 769 ENVYRKSGGSGKLPIKWLALESLTHQV--YTSQSDVWSFGVLLYEITTLGGMPYPSVSPS 826
Query 822 EKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
+ ++ HR+ PE ++ +L C + P+ RP+F + H L ++
Sbjct 827 DLLQLLRQGHRMKRPEGCTQEMFSLMESCWSSVPSHRPTFSAL--------KHRLGGMIL 878
Query 880 VNPDSP 885
D P
Sbjct 879 ATNDVP 884
Score = 36.6 bits (83), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 29/89 (33%), Positives = 44/89 (49%), Gaps = 8/89 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961
LGEG FG V Y VAVK LK + + +K EI +L+ + H +I+
Sbjct 481 LGEGAFGLVRRGVY------KKRQVAVKLLKDEPNDEDVYAFKCEIQMLKAVGKHPNIVG 534
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
G + + L++EY LGSL+++L
Sbjct 535 IVGYST-RFSNQMMLLIEYCSLGSLQNFL 562
>sp|Q01887|RYK_MOUSE Tyrosine-protein kinase RYK OS=Mus musculus
OX=10090 GN=Ryk PE=1 SV=2
Length=594
Score = 124 bits (312), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 95/317 (30%), Positives = 156/317 (49%), Gaps = 29/317 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRY-LKKIRDLGEGHFGKVSL-YCYDPTNDGTGE 925
R++ ++L V + + D + +R LK + L EG FG++ D + +
Sbjct 289 RIEKNDLRSVTLLEAKAKVKDIAISRERITLKDV--LQEGTFGRIFHGILVDEKDPNKEK 346
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
VK +K + E LR L+H +++ C ++GEK + +V+ Y+ G+
Sbjct 347 QTFVKTVKDQASEVQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPM-VVLPYMNWGN 405
Query 986 LRDYLPR---------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036
L+ +L + +I L+ A QI GM+YL + IHRDLAARN ++D+
Sbjct 406 LKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHRDLAARNCVIDDTLQ 465
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
VKI D L++ + +Y+ + ++ + PV W A E L +F ASDVW+FGVTL+EL+T
Sbjct 466 VKITDNALSRDLFP-MDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMT 524
Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156
Q+P + I +M L+ G R+ +P CP E++ +M CW +
Sbjct 525 ---LGQTP------YVDIDPFEMAA-----YLKDGYRIAQPINCPDELFAVMACCWALDP 570
Query 1157 SFRPTFENLIPILKTVH 1173
RP F+ L+ L H
Sbjct 571 EERPKFQQLVQCLTEFH 587
Score = 72.8 bits (177), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 66/265 (25%), Positives = 125/265 (47%), Gaps = 36/265 (14%)
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL-MSQVSHTHLAFVHGVCVR-GPENI 684
LV +D +E + +K + ++ + T S + + H +L + VC+ G + +
Sbjct 336 LVDEKDPNKEKQTFVKTVKDQASEVQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPM 395
Query 685 MVTEYVEHGPLDVWLRRER---GHVPMAWK----MVVAQQLASALSYLENKNLVHGNVCG 737
+V Y+ G L ++LR+ + + P A + +A Q+A +SYL + ++H ++
Sbjct 396 VVLPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHRDLAA 455
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSRE----------ERVER-IPWLAPECLPG 786
RN ++ + +K++D ALSR+ + R + W+A E L
Sbjct 456 RNCVI-------DDTLQVKITD-----NALSRDLFPMDYHCLGDNENRPVRWMALESLVN 503
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATL 844
N S+A D W FG TL E+ G+ P P E + + +R+ +P +CP +L +
Sbjct 504 --NEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAV 561
Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869
+ C +P +RP F+ +++ LT
Sbjct 562 MACCWALDPEERPKFQQLVQCLTEF 586
>sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kinase
11 OS=Rattus norvegicus OX=10116 GN=Map3k11 PE=1 SV=1
Length=850
Score = 125 bits (315), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 101/304 (33%), Positives = 145/304 (48%), Gaps = 43/304 (14%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ---HRSGWKQEI 948
F + L+++ +G G FGKV + GE+VAVKA + D +QE
Sbjct 115 FQELRLEEV--IGIGGFGKVYRGSW------RGELVAVKAARQDPDEDISVTAESVRQEA 166
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008
+ L H +II K C + E +L LVMEY G L L + L+ +A QI
Sbjct 167 RLFAMLAHPNIIALKAVCLE--EPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIA 224
Query 1009 EGMAYLHAQH---YIHRDLAARNVLL----DND----RLVKIGDFGLAKAVPEGHEYYRV 1057
GM YLH + IHRDL + N+LL + D + +KI DFGLA+ E H+ ++
Sbjct 225 RGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAR---EWHKTTQM 281
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
G W APE +K F SDVWSFGV L+ELLT P + ++ + +A G
Sbjct 282 SAAGT--YAWMAPEVIKASTFSKGSDVWSFGVLLWELLTG-----EVPYRGIDCLAVAYG 334
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
+ V +LT LP P CP LM +CW + RP F +++ L+ + +
Sbjct 335 -VAVNKLT--------LPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVL 385
Query 1178 GQAP 1181
+ P
Sbjct 386 REMP 389
Score = 68.6 bits (166), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 77/264 (29%), Positives = 120/264 (45%), Gaps = 26/264 (10%)
Query 630 GRDRGQELRVVLKVLDPSHHDIAL---AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
G RG+ + V DP DI++ + + A L + ++H ++ + VC+ P +V
Sbjct 135 GSWRGELVAVKAARQDP-DEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLV 193
Query 687 TEYVEHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKNLV---HGNVCGRNIL 741
EY GPL L RR HV + W A Q+A + YL + LV H ++ NIL
Sbjct 194 MEYAAGGPLSRALAGRRVPPHVLVNW----AVQIARGMHYLHCEALVPVIHRDLKSNNIL 249
Query 742 LARLGLAEGTS---PFIKLSDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMD 796
L L EG +K++D G+ ++ W+APE + A++ S D
Sbjct 250 L--LQPIEGDDMEHKTLKITDFGLAREWHKTTQMSAAGTYAWMAPEVI--KASTFSKGSD 305
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEP 853
W FG L E+ GE P + + + LP PS CP+ A L + C +P
Sbjct 306 VWSFGVLLWEL-LTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDP 364
Query 854 TQRPSFRTILRDLTRLQPHNLADV 877
+RP F +IL+ L L+ L ++
Sbjct 365 HRRPDFASILQQLEALEAQVLREM 388
>sp|Q91571|EPB1A_XENLA Ephrin type-B receptor 1-A OS=Xenopus laevis
OX=8355 GN=ephb1-a PE=1 SV=1
Length=985
Score = 126 bits (316), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 71/248 (29%), Positives = 127/248 (51%), Gaps = 20/248 (8%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VA+K LKA + R + E I+ H +II+ +G + + ++ E++ G+L
Sbjct 649 VAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGAL 706
Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL
Sbjct 707 DSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGL 766
Query 1045 AKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
++ + + Y G PV W A E + KF ASDVWS+G+ ++E++++ +
Sbjct 767 SRYLQDDTSDPTYTSSLGGKIPVRWTAQEAIAYRKFTSASDVWSYGIVMWEVMSYGER-- 824
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
M+ + +E+ RLP P CP ++ LM +CW+ + + RP
Sbjct 825 ------------PYWTMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRL 872
Query 1163 ENLIPILK 1170
++ L+
Sbjct 873 AEIVNTLR 880
Score = 84.7 bits (208), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 78/315 (25%), Positives = 138/315 (44%), Gaps = 50/315 (16%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653
+G G VY+GRL++ P + +E+ V +K L + +
Sbjct 626 IGAGEFGEVYKGRLKL------------------PSK---REISVAIKTLKAGYSEKQRR 664
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F AS+M Q H ++ + GV + +++TE++E+G LD +LR+ G + +
Sbjct 665 DFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVG 724
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
+ + +A+ + YL N VH ++ RNIL+ ++ K+SD GL +++
Sbjct 725 MLRGIAAGMKYLSEMNYVHRDLAARNILV-------NSNLVCKVSD--FGLSRYLQDDTS 775
Query 774 E---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ +IP W A E + ++A D W +G + E+ GE P + S +
Sbjct 776 DPTYTSSLGGKIPVRWTAQEAI--AYRKFTSASDVWSYGIVMWEVMSYGERPYWTMSNQD 833
Query 823 KEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVL 878
+ ++ +RLP P CP L L C + RP I+ L + P +L V
Sbjct 834 VINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRLAEIVNTLRPMIRNPASLKTVA 893
Query 879 TV--NPDSPASDPTV 891
T+ P P D ++
Sbjct 894 TIPAVPSQPLLDRSI 908
>sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase
kinase 11 OS=Mus musculus OX=10090 GN=Map3k11 PE=1 SV=1
Length=850
Score = 125 bits (315), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 101/304 (33%), Positives = 145/304 (48%), Gaps = 43/304 (14%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ---HRSGWKQEI 948
F + L+++ +G G FGKV + GE+VAVKA + D +QE
Sbjct 115 FQELRLEEV--IGIGGFGKVYRGSW------RGELVAVKAARQDPDEDISVTAESVRQEA 166
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008
+ L H +II K C + E +L LVMEY G L L + L+ +A QI
Sbjct 167 RLFAMLAHPNIIALKAVCLE--EPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIA 224
Query 1009 EGMAYLHAQH---YIHRDLAARNVLL----DND----RLVKIGDFGLAKAVPEGHEYYRV 1057
GM YLH + IHRDL + N+LL + D + +KI DFGLA+ E H+ ++
Sbjct 225 RGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAR---EWHKTTQM 281
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
G W APE +K F SDVWSFGV L+ELLT P + ++ + +A G
Sbjct 282 SAAGT--YAWMAPEVIKASTFSKGSDVWSFGVLLWELLTG-----EVPYRGIDCLAVAYG 334
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
+ V +LT LP P CP LM +CW + RP F +++ L+ + +
Sbjct 335 -VAVNKLT--------LPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVL 385
Query 1178 GQAP 1181
+ P
Sbjct 386 REMP 389
Score = 68.2 bits (165), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 77/264 (29%), Positives = 120/264 (45%), Gaps = 26/264 (10%)
Query 630 GRDRGQELRVVLKVLDPSHHDIAL---AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
G RG+ + V DP DI++ + + A L + ++H ++ + VC+ P +V
Sbjct 135 GSWRGELVAVKAARQDP-DEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLV 193
Query 687 TEYVEHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKNLV---HGNVCGRNIL 741
EY GPL L RR HV + W A Q+A + YL + LV H ++ NIL
Sbjct 194 MEYAAGGPLSRALAGRRVPPHVLVNW----AVQIARGMHYLHCEALVPVIHRDLKSNNIL 249
Query 742 LARLGLAEGTS---PFIKLSDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMD 796
L L EG +K++D G+ ++ W+APE + A++ S D
Sbjct 250 L--LQPIEGDDMEHKTLKITDFGLAREWHKTTQMSAAGTYAWMAPEVI--KASTFSKGSD 305
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEP 853
W FG L E+ GE P + + + LP PS CP+ A L + C +P
Sbjct 306 VWSFGVLLWEL-LTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDP 364
Query 854 TQRPSFRTILRDLTRLQPHNLADV 877
+RP F +IL+ L L+ L ++
Sbjct 365 HRRPDFASILQQLEALEAQVLREM 388
>sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase
kinase 11 OS=Homo sapiens OX=9606 GN=MAP3K11 PE=1 SV=1
Length=847
Score = 125 bits (315), Expect = 6e-28, Method: Compositional matrix adjust.
Identities = 101/304 (33%), Positives = 146/304 (48%), Gaps = 43/304 (14%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ---HRSGWKQEI 948
F + L+++ +G G FGKV + GE+VAVKA + D +QE
Sbjct 114 FQELRLEEV--IGIGGFGKVYRGSW------RGELVAVKAARQDPDEDISVTAESVRQEA 165
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008
+ L H +II K C + E +L LVMEY G L L + L+ +A QI
Sbjct 166 RLFAMLAHPNIIALKAVCLE--EPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIA 223
Query 1009 EGMAYLHAQH---YIHRDLAARNVLL----DND----RLVKIGDFGLAKAVPEGHEYYRV 1057
GM YLH + IHRDL + N+LL ++D + +KI DFGLA+ E H+ ++
Sbjct 224 RGMHYLHCEALVPVIHRDLKSNNILLLQPIESDDMEHKTLKITDFGLAR---EWHKTTQM 280
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
G W APE +K F SDVWSFGV L+ELLT P + ++ + +A G
Sbjct 281 SAAGT--YAWMAPEVIKASTFSKGSDVWSFGVLLWELLTG-----EVPYRGIDCLAVAYG 333
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
+ V +LT LP P CP LM +CW + RP F +++ L+ + +
Sbjct 334 -VAVNKLT--------LPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVL 384
Query 1178 GQAP 1181
+ P
Sbjct 385 REMP 388
Score = 67.4 bits (163), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 74/262 (28%), Positives = 120/262 (46%), Gaps = 22/262 (8%)
Query 630 GRDRGQELRVVLKVLDPSHHDIAL---AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
G RG+ + V DP DI++ + + A L + ++H ++ + VC+ P +V
Sbjct 134 GSWRGELVAVKAARQDP-DEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLV 192
Query 687 TEYVEHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKNLV---HGNVCGRNIL 741
EY GPL L RR HV + W A Q+A + YL + LV H ++ NIL
Sbjct 193 MEYAAGGPLSRALAGRRVPPHVLVNW----AVQIARGMHYLHCEALVPVIHRDLKSNNIL 248
Query 742 LAR-LGLAEGTSPFIKLSDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMDKW 798
L + + + +K++D G+ ++ W+APE + A++ S D W
Sbjct 249 LLQPIESDDMEHKTLKITDFGLAREWHKTTQMSAAGTYAWMAPEVI--KASTFSKGSDVW 306
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQ 855
FG L E+ GE P + + + LP PS CP+ A L + C +P +
Sbjct 307 SFGVLLWEL-LTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHR 365
Query 856 RPSFRTILRDLTRLQPHNLADV 877
RP F +IL+ L L+ L ++
Sbjct 366 RPDFASILQQLEALEAQVLREM 387
>sp|O13147|EPHB3_DANRE Ephrin type-B receptor 3 (Fragment) OS=Danio
rerio OX=7955 GN=ephb3 PE=2 SV=1
Length=500
Score = 122 bits (307), Expect = 7e-28, Method: Compositional matrix adjust.
Identities = 82/273 (30%), Positives = 131/273 (48%), Gaps = 25/273 (9%)
Query 903 LGEGHFGKVSLYCYDPTND-GTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G FG+V C G E VA+K LKA R + E I+ H ++I
Sbjct 193 IGAGEFGEV---CRGRLKQAGRKETTVAIKTLKAGYTEHQRRDFLSEASIMGQFDHPNVI 249
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018
+G + +V E++ G+L +L + + QL+ + I GM YL +
Sbjct 250 HLEGVLTRSC--PVLIVTEFMENGALDSFLRLNDGRFTVTQLVGMLRGIAAGMKYLSDMN 307
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076
Y+HRDLAARNVL++++ + K+ DFGL++ + + Y G P+ W APE +
Sbjct 308 YVHRDLAARNVLVNSNLVCKVSDFGLSRFLDDNSSDPTYTSSLGGKIPIRWTAPEAIAFR 367
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
KF ASDVWS+G+ ++E+++ + M+ + +E+ RLP
Sbjct 368 KFTSASDVWSYGIVMWEVMSFGER--------------PYWDMSNQDVMNAVEQDYRLPP 413
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P CP ++ LM CW E + RP F ++ L
Sbjct 414 PMDCPAVLHQLMLECWVKERNMRPRFGQIVSTL 446
Score = 88.2 bits (217), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 66/227 (29%), Positives = 106/227 (47%), Gaps = 22/227 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F AS+M Q H ++ + GV R ++VTE++E+G LD +LR G + + +
Sbjct 233 FLSEASIMGQFDHPNVIHLEGVLTRSCPVLIVTEFMENGALDSFLRLNDGRFTVTQLVGM 292
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFI--KLSDPGV--GLGA 766
+ +A+ + YL + N VH ++ RN+L+ + + G S F+ SDP LG
Sbjct 293 LRGIAAGMKYLSDMNYVHRDLAARNVLVNSNLVCKVSDFGLSRFLDDNSSDPTYTSSLGG 352
Query 767 LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+IP W APE + ++A D W +G + E+ GE P S +
Sbjct 353 --------KIPIRWTAPEAI--AFRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVM 402
Query 825 HFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ ++ +RLP P CP L L +C E RP F I+ L +
Sbjct 403 NAVEQDYRLPPPMDCPAVLHQLMLECWVKERNMRPRFGQIVSTLDKF 449
>sp|Q9I8N6|CSF1R_DANRE Macrophage colony-stimulating factor 1
receptor OS=Danio rerio OX=7955 GN=csf1r PE=2 SV=1
Length=977
Score = 125 bits (315), Expect = 8e-28, Method: Compositional matrix adjust.
Identities = 106/394 (27%), Positives = 169/394 (43%), Gaps = 89/394 (23%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS-PASDPTVFHKRYLKKIRDLGEGH 907
+ Y+ Q+P + + + +N ++P P ++ F + LK + LG G
Sbjct 538 MIYKYKQKPRYEIRWKIIEATNGNNYT---FIDPTQLPYNEKWEFPRDKLKLGKTLGAGA 594
Query 908 FGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKG- 964
FGKV Y + VAVK LKA P R E+ IL L H++I+ G
Sbjct 595 FGKVVEATAYGLGKEDNITRVAVKMLKASAHPDEREALMSELKILSHLGQHKNIVNLLGA 654
Query 965 -------------CC--------EDQGEKSLQLVM----------EYVPLGSLRDYL--- 990
CC + E L VM +Y + + R ++
Sbjct 655 CTHGGPVLVITEYCCHGDLLNFLRSKAENFLNFVMTIPNFPEPMTDYKNVSTERMFVRSD 714
Query 991 --------------------PRHS--------------IGLAQLLLFAQQICEGMAYLHA 1016
P +S + + LL F+ Q+ +G+ +L A
Sbjct 715 SGISSTCSDHYLDMRPVTSRPTNSALDSSSECQEDSWPLDMDDLLRFSSQVAQGLDFLAA 774
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
++ IHRD+AARNVLL N R+ KI DFGLA+ + Y V+ + PV W APE + E
Sbjct 775 KNCIHRDVAARNVLLTNSRVAKICDFGLARDIMNDSNYV-VKGNARLPVKWMAPESIFEC 833
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+ SDVWS+G+ L+E+ + +SP L + ++++ G ++ R
Sbjct 834 VYTVQSDVWSYGIMLWEIFSL---GKSPYPNIL----------VDSKFYKMIKCGYQMSR 880
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
PD P E+Y +MK CW +A+ RPTF + +++
Sbjct 881 PDFAPPEMYTIMKMCWNLDAAERPTFSKISQMIQ 914
Score = 57.8 bits (138), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 42/166 (25%), Positives = 76/166 (46%), Gaps = 22/166 (13%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ Q+A L +L KN +H +V RN+LL +A K+ D G+ ++ V
Sbjct 762 SSQVAQGLDFLAAKNCIHRDVAARNVLLTNSRVA-------KICDFGLARDIMNDSNYVV 814
Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
+ + W+APE + ++ + D W +G L EI G++P + K FY+
Sbjct 815 KGNARLPVKWMAPESIFECVYTVQS--DVWSYGIMLWEIFSLGKSPYPNILVDSK--FYK 870
Query 829 R-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
Q P+ + P++ T+ C + +RP+F I + + R+
Sbjct 871 MIKCGYQMSRPDFAPPEMYTIMKMCWNLDAAERPTFSKISQMIQRM 916
>sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens
OX=9606 GN=EPHB4 PE=1 SV=2
Length=987
Score = 125 bits (314), Expect = 8e-28, Method: Compositional matrix adjust.
Identities = 81/280 (29%), Positives = 136/280 (49%), Gaps = 25/280 (9%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTND-GTGE-MVAVKALKADCGPQHRSGWKQEIDILRT 953
Y+K +G G FG+V C G E VA+K LK + R + E I+
Sbjct 614 YVKIEEVIGAGEFGEV---CRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQ 670
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGM 1011
H +II+ +G + + ++ E++ G+L +L + + QL+ + I GM
Sbjct 671 FEHPNIIRLEGVVTNS--MPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYA 1069
YL Y+HRDLAARN+L++++ + K+ DFGL++ + E Y G P+ W A
Sbjct 729 RYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTA 788
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE + KF ASD WS+G+ ++E+++ + M+ + +E
Sbjct 789 PEAIAFRKFTSASDAWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIE 834
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ RLP P CP ++ LM +CW+ + + RP F ++ L
Sbjct 835 QDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSAL 874
Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 64/254 (25%), Positives = 113/254 (44%), Gaps = 24/254 (9%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F AS+M Q H ++ + GV +++TE++E+G LD +LR G + + +
Sbjct 661 FLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGM 720
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ +AS + YL + VH ++ RNIL+ ++ K+SD GL E +
Sbjct 721 LRGIASGMRYLAEMSYVHRDLAARNILV-------NSNLVCKVSD--FGLSRFLEENSSD 771
Query 775 ---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+IP W APE + ++A D W +G + E+ GE P S +
Sbjct 772 PTYTSSLGGKIPIRWTAPEAI--AFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDV 829
Query 824 EHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
+ ++ +RL P P CP L L C + RP F ++ L ++ + + +
Sbjct 830 INAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVAR 889
Query 882 PDSPASDPTVFHKR 895
+ AS P + ++
Sbjct 890 ENGGASHPLLDQRQ 903
>sp|O73878|EPB4B_DANRE Ephrin type-B receptor 4b OS=Danio rerio
OX=7955 GN=ephb4b PE=1 SV=2
Length=976
Score = 125 bits (314), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 83/280 (30%), Positives = 135/280 (48%), Gaps = 25/280 (9%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTN-DGTGE-MVAVKALKADCGPQHRSGWKQEIDILRT 953
++K +G G FG+V C G E VA+K LK + R + E I+
Sbjct 612 FVKIEEVIGAGEFGEV---CRGRLKVPGKKENYVAIKTLKGGYTDKQRRDFLSEASIMGQ 668
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGM 1011
H +II +G + ++ EY+ G+L +L + QL+ + I GM
Sbjct 669 FQHPNIIHLEGVI--TASCPVMILTEYMENGALDSFLRLNDGQFTPIQLVGMLRGIASGM 726
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYA 1069
YL ++HRDLAARN+L++++ + K+ DFGL++ + E Y G P+ W A
Sbjct 727 KYLSEMSFVHRDLAARNILVNSNLVCKVSDFGLSRFLTENSSDPTYTSSLGGKIPIRWTA 786
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE + KF ASDVWS+G+ ++E+++ + M+ + +E
Sbjct 787 PEAIAFRKFTSASDVWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIE 832
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ RLP P +CP ++ LM +CW+ E S RP F ++ L
Sbjct 833 QDYRLPPPPECPASLHQLMLDCWQKERSSRPRFCAIVSAL 872
Score = 87.8 bits (216), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 79/275 (29%), Positives = 123/275 (45%), Gaps = 31/275 (11%)
Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
VPG+ +E V +K L + D F AS+M Q H ++ + GV +++
Sbjct 634 VPGK---KENYVAIKTLKGGYTDKQRRDFLSEASIMGQFQHPNIIHLEGVITASCPVMIL 690
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TEY+E+G LD +LR G + + + +AS + YL + VH ++ RNIL+
Sbjct 691 TEYMENGALDSFLRLNDGQFTPIQLVGMLRGIASGMKYLSEMSFVHRDLAARNILV---- 746
Query 747 LAEGTSPFIKLSDPGVGLGALSREERVE---------RIP--WLAPECLPGGANSLSTAM 795
++ K+SD GL E + +IP W APE + ++A
Sbjct 747 ---NSNLVCKVSD--FGLSRFLTENSSDPTYTSSLGGKIPIRWTAPEAI--AFRKFTSAS 799
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEP 853
D W +G + E+ GE P S + + ++ +RL P P CP L L C E
Sbjct 800 DVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPECPASLHQLMLDCWQKER 859
Query 854 TQRPSFRTILRDLTRL--QPHNLADVLTVNPDSPA 886
+ RP F I+ L RL P +L + PD P+
Sbjct 860 SSRPRFCAIVSALDRLIRNPASLKITGRI-PDGPS 893
>sp|P30530|UFO_HUMAN Tyrosine-protein kinase receptor UFO OS=Homo
sapiens OX=9606 GN=AXL PE=1 SV=4
Length=894
Score = 125 bits (313), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 91/285 (32%), Positives = 134/285 (47%), Gaps = 31/285 (11%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDIL 951
HK L K LGEG FG V + D + VAVK +K A C + E +
Sbjct 534 HKVALGKT--LGEGEFGAVMEGQLN--QDDSILKVAVKTMKIAICTRSELEDFLSEAVCM 589
Query 952 RTLYHEHIIKYKGCCEDQGEK----SLQLVMEYVPLGSLRDYLPRHSIG-------LAQL 1000
+ H ++++ G C E+ + +++ ++ G L +L +G L
Sbjct 590 KEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGDQPVYLPTQML 649
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+ F I GM YL + +IHRDLAARN +L+ + V + DFGL+K + G +YYR
Sbjct 650 VKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNG-DYYRQGRI 708
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
PV W A E L + + SDVWSFGVT++E+ T Q+P G+ +
Sbjct 709 AKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATR---GQTP------YPGVENSE-- 757
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + L +G RL +P C +Y LM CWE RP+F L
Sbjct 758 ---IYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTEL 799
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 82/316 (26%), Positives = 135/316 (43%), Gaps = 55/316 (17%)
Query 600 RTNVYEGRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA---- 654
R V G+ EG G EG+++ +D + L+V +K + IA+
Sbjct 533 RHKVALGKTLGEGEFGAVMEGQLNQDDSI---------LKVAVKTMK-----IAICTRSE 578
Query 655 ---FYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEYVEHGPLDVWLRRER-- 703
F A M + H ++ + GVC +G P +++ +++HG L +L R
Sbjct 579 LEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLG 638
Query 704 ---GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
++P + +AS + YL K +H ++ RN +L E S + ++D
Sbjct 639 DQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLN-----ENMS--VCVADF 691
Query 761 GVGL----GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ G R+ R+ ++P W+A E L ++ D W FG T+ EI G+ P
Sbjct 692 GLSKKIYNGDYYRQGRIAKMPVKWIAIESL--ADRVYTSKSDVWSFGVTMWEIATRGQTP 749
Query 815 LQSRSPSEKEHFYQRQHRLPEPS--CPQLATLTSQCLTYEPTQRPSFRTILRDLTR---- 868
SE + ++ +RL +P+ L L S+C P RPSF + DL
Sbjct 750 YPGVENSEIYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTELREDLENTLKA 809
Query 869 LQPHNLAD-VLTVNPD 883
L P D +L VN D
Sbjct 810 LPPAQEPDEILYVNMD 825
>sp|O73792|TIE1_DANRE Tyrosine-protein kinase receptor Tie-1 (Fragment)
OS=Danio rerio OX=7955 GN=tie1 PE=1 SV=1
Length=184
Score = 114 bits (285), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 69/176 (39%), Positives = 90/176 (51%), Gaps = 18/176 (10%)
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
QLL FA + GM YL + +IHRDLAARNVL+ ++ + KI DFGL++ G E Y +
Sbjct 1 QLLQFAADVATGMHYLSDKQFIHRDLAARNVLVGDNLVAKIADFGLSR----GEEVYVKK 56
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
G PV W A E L + SDVWSFGV L+E+++ L G
Sbjct 57 TMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCG 102
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
MT L E L +G R+ +P C EVY LM+ CW RP F + L + E
Sbjct 103 MTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRMQE 158
Score = 59.7 bits (143), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 47/168 (28%), Positives = 79/168 (47%), Gaps = 14/168 (8%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERV 773
A +A+ + YL +K +H ++ RN+L+ G + K++D G+ G + ++ +
Sbjct 6 AADVATGMHYLSDKQFIHRDLAARNVLV-------GDNLVAKIADFGLSRGEEVYVKKTM 58
Query 774 ERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
R+P W+A E L + +T D W FG L EI G P + +E + +
Sbjct 59 GRLPVRWMAIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGY 116
Query 832 RLPEP-SC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
R+ +P +C ++ L QC P +RP F I L R+Q A V
Sbjct 117 RMEQPRNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRMQEARKAYV 164
>sp|P97793|ALK_MOUSE ALK tyrosine kinase receptor OS=Mus musculus
OX=10090 GN=Alk PE=1 SV=2
Length=1621
Score = 125 bits (314), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 100/330 (30%), Positives = 146/330 (44%), Gaps = 41/330 (12%)
Query 855 QRPSFR-TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV-S 912
Q P ++ + LR T + +N + S SD ++ + IR LG G FG+V
Sbjct 1078 QSPEYKLSKLRTSTIMTDYN-PNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYE 1136
Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972
ND + VAVK L C Q + E I+ H++I++ G
Sbjct 1137 GQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGV------- 1189
Query 973 SLQ-----LVMEYVPLGSLRDYL----PR----HSIGLAQLLLFAQQICEGMAYLHAQHY 1019
SLQ +++E + G L+ +L PR S+ + LL A+ I G YL H+
Sbjct 1190 SLQALPRFILLELMAGGDLKSFLRETRPRPNQPTSLAMLDLLHVARDIACGCQYLEENHF 1249
Query 1020 IHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+AARN LL R+ KIGDFG+A+ + YYR PV W PE E
Sbjct 1250 IHRDIAARNCLLTCPGAGRIAKIGDFGMARDIYRA-SYYRKGGCAMLPVKWMPPEAFMEG 1308
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
F +D WSFGV L+E+ + L + + + E + G R+
Sbjct 1309 IFTSKTDTWSFGVLLWEIFS--------------LGYMPYPSKSNQEVLEFVTSGGRMDP 1354
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
P CP VY +M CW+ + RP F ++
Sbjct 1355 PKNCPGPVYRIMTQCWQHQPEDRPNFAIIL 1384
Score = 84.3 bits (207), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 85/310 (27%), Positives = 135/310 (44%), Gaps = 42/310 (14%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
+T ++S L V +K IT + LG G VYEG++ SG P +D PL
Sbjct 1105 KTSSISDLK--EVPRKNITLIRGLGHGAFGEVYEGQV----SGMP-----NDPSPL---- 1149
Query 632 DRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
+V +K L + L F A ++S+ +H ++ GV ++ ++ E +
Sbjct 1150 ------QVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELM 1203
Query 691 EHGPLDVWLR--RERGHVPMAWKMV----VAQQLASALSYLENKNLVHGNVCGRNILLAR 744
G L +LR R R + P + M+ VA+ +A YLE + +H ++ RN LL
Sbjct 1204 AGGDLKSFLRETRPRPNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLT- 1262
Query 745 LGLAEGTSPFIKLSDPGVG----LGALSREERVERIP--WLAPECLPGGANSLSTAMDKW 798
G K+ D G+ + R+ +P W+ PE G ++ D W
Sbjct 1263 ---CPGAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGI--FTSKTDTW 1317
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQR 856
FG L EI G P S+S E F R+ P +CP + + +QC ++P R
Sbjct 1318 SFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDR 1377
Query 857 PSFRTILRDL 866
P+F IL +
Sbjct 1378 PNFAIILERI 1387
>sp|Q5JZY3|EPHAA_HUMAN Ephrin type-A receptor 10 OS=Homo sapiens
OX=9606 GN=EPHA10 PE=1 SV=2
Length=1008
Score = 124 bits (312), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 87/275 (32%), Positives = 127/275 (46%), Gaps = 23/275 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
R LG G FG++ C G E+ VAV L+ R G+ E L H HI
Sbjct 649 RSLGGGRFGELCCGCLQ--LPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHI 706
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQ 1017
++ +G +L +V EY+ G+L +L RH L QL+ + M YL
Sbjct 707 VRLEGVVTRG--STLMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEM 764
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
Y+HR LAAR+VL+ +D + KI FG + + E G SP W APE L+
Sbjct 765 GYVHRGLAARHVLVSSDLVCKISGFG--RGPRDRSEAVYTTMSGRSPALWAAPETLQFGH 822
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F ASDVWSFG+ ++E++ + M+ + + +E G RLP P
Sbjct 823 FSSASDVWSFGIIMWEVMAFGERP--------------YWDMSGQDVIKAVEDGFRLPPP 868
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
CP ++ LM +CW+ + RP F + IL +
Sbjct 869 RNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKM 903
Score = 105 bits (262), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 90/275 (33%), Positives = 125/275 (45%), Gaps = 28/275 (10%)
Query 628 VPGRDRGQELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+PGR QEL V + +L S D L F A + Q H+H+ + GV RG ++V
Sbjct 666 LPGR---QELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIV 722
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TEY+ HG LD +LRR G + M + LASA+ YL VH + R++L++
Sbjct 723 TEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVS--- 779
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-----ERIP--WLAPECLPGGANSLSTAMDKWG 799
+ K+S G G G R E V R P W APE L G S+A D W
Sbjct 780 ----SDLVCKIS--GFGRGPRDRSEAVYTTMSGRSPALWAAPETLQFG--HFSSASDVWS 831
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQLA-TLTSQCLTYEPTQRP 857
FG + E+ GE P S + + RLP P +CP L L C +P +RP
Sbjct 832 FGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERP 891
Query 858 SFRTILRDLTRL----QPHNLADVLTVNPDSPASD 888
F I L+++ +P A P +P +D
Sbjct 892 RFSQIHSILSKMVQDPEPPKCALTTCPRPPTPLAD 926
>sp|O73875|EPB4A_DANRE Ephrin type-B receptor 4a OS=Danio rerio
OX=7955 GN=ephb4a PE=1 SV=3
Length=987
Score = 124 bits (312), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 74/247 (30%), Positives = 122/247 (49%), Gaps = 20/247 (8%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VA+K LK + R + E I+ H +II +G + ++ E++ G+L
Sbjct 650 VAIKTLKGGYTDKQRRDFLAEASIMGQFQHPNIIHLEGII--TASCPVMILTEFMENGAL 707
Query 987 RDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
+L + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL
Sbjct 708 DSFLRLNDGQFTPIQLVGMLRGIASGMKYLSEMSYVHRDLAARNILVNSNLVCKVSDFGL 767
Query 1045 AKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
++ + E Y G P+ W APE + KF ASDVWS+G+ ++E+++ +
Sbjct 768 SRFLQENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTCASDVWSYGIVMWEVMSFGER-- 825
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
M+ + +E+ RLP P CP ++ LM +CW+ E + RP F
Sbjct 826 ------------PYWDMSNQDVINAIEQDYRLPPPPDCPTYLHQLMLDCWQKERTARPRF 873
Query 1163 ENLIPIL 1169
N++ L
Sbjct 874 ANIVSAL 880
Score = 84.7 bits (208), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 78/289 (27%), Positives = 123/289 (43%), Gaps = 46/289 (16%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653
+G G V GRLR+ PG+ +E V +K L + D
Sbjct 627 IGAGEFGEVCRGRLRI------------------PGK---KENYVAIKTLKGGYTDKQRR 665
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F AS+M Q H ++ + G+ +++TE++E+G LD +LR G +
Sbjct 666 DFLAEASIMGQFQHPNIIHLEGIITASCPVMILTEFMENGALDSFLRLNDGQFTPIQLVG 725
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
+ + +AS + YL + VH ++ RNIL+ ++ K+SD GL +E
Sbjct 726 MLRGIASGMKYLSEMSYVHRDLAARNILV-------NSNLVCKVSD--FGLSRFLQENSS 776
Query 774 E---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ +IP W APE + + A D W +G + E+ GE P S +
Sbjct 777 DPTYTSSLGGKIPIRWTAPEAI--AFRKFTCASDVWSYGIVMWEVMSFGERPYWDMSNQD 834
Query 823 KEHFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ ++ +RL P P CP L L C E T RP F I+ L +L
Sbjct 835 VINAIEQDYRLPPPPDCPTYLHQLMLDCWQKERTARPRFANIVSALDKL 883
>sp|P08923|LTK_MOUSE Leukocyte tyrosine kinase receptor OS=Mus
musculus OX=10090 GN=Ltk PE=1 SV=3
Length=888
Score = 124 bits (312), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 94/300 (31%), Positives = 140/300 (47%), Gaps = 38/300 (13%)
Query 900 IRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+R LG G FG+V L P D + VA+K L C Q + E I+ H+
Sbjct 509 LRALGHGAFGEVYEGLVTGLP-GDSSPLPVAIKTLPELCSHQDELDFLMEALIISKFSHQ 567
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------IGLAQLLLFAQQIC 1008
+I++ G + +++E + G ++ +L RHS + + LL AQ I
Sbjct 568 NIVRCVGLSFRSAPR--LILLELMSGGDMKSFL-RHSRPHPGQLAPLTMQDLLQLAQDIA 624
Query 1009 EGMAYLHAQHYIHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
+G YL H+IHRD+AARN LL R+ KIGDFG+A+ + + YYR PV
Sbjct 625 QGCHYLEENHFIHRDIAARNCLLSCSGASRVAKIGDFGMARDIYQA-SYYRKGGRTLLPV 683
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
W PE L E F +D WSFGV L+E+ + ++ G T +
Sbjct 684 KWMPPEALLEGLFTSKTDSWSFGVLLWEIFS---------LGYMPYPG-----HTNQEVL 729
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
+ + G R+ P CP VY +M CW+ + RP F + IL+ + +Y Q P V +
Sbjct 730 DFIATGNRMDPPRNCPGPVYRIMTQCWQHQPELRPDFGS---ILERI--QYCTQDPDVLN 784
Score = 80.9 bits (198), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 86/317 (27%), Positives = 130/317 (41%), Gaps = 44/317 (14%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +T L LG G VYEG + G D PL V +K
Sbjct 501 VSPANVTLLRALGHGAFGEVYEGLV---------TGLPGDSSPL----------PVAIKT 541
Query 644 LDP--SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
L SH D L F A ++S+ SH ++ G+ R +++ E + G + +LR
Sbjct 542 LPELCSHQD-ELDFLMEALIISKFSHQNIVRCVGLSFRSAPRLILLELMSGGDMKSFLRH 600
Query 702 ERGH----VPMAWK--MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
R H P+ + + +AQ +A YLE + +H ++ RN LL+ G S
Sbjct 601 SRPHPGQLAPLTMQDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLS----CSGASRVA 656
Query 756 KLSDPGVG----LGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
K+ D G+ + R+ +P W+ PE L G ++ D W FG L EI
Sbjct 657 KIGDFGMARDIYQASYYRKGGRTLLPVKWMPPEALLEGL--FTSKTDSWSFGVLLWEIFS 714
Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLT 867
G P + E F +R+ P +CP + + +QC ++P RP F +IL +
Sbjct 715 LGYMPYPGHTNQEVLDFIATGNRMDPPRNCPGPVYRIMTQCWQHQPELRPDFGSILERIQ 774
Query 868 RL--QPHNLADVLTVNP 882
P L L V P
Sbjct 775 YCTQDPDVLNSPLPVEP 791
>sp|P54761|EPHB4_MOUSE Ephrin type-B receptor 4 OS=Mus musculus
OX=10090 GN=Ephb4 PE=1 SV=2
Length=987
Score = 124 bits (312), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 81/280 (29%), Positives = 136/280 (49%), Gaps = 25/280 (9%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTND-GTGE-MVAVKALKADCGPQHRSGWKQEIDILRT 953
Y+K +G G FG+V C G E VA+K LK + R + E I+
Sbjct 614 YVKIEEVIGAGEFGEV---CRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQ 670
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGM 1011
H +II+ +G + + ++ E++ G+L +L + + QL+ + I GM
Sbjct 671 FEHPNIIRLEGVVTNS--VPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYA 1069
YL Y+HRDLAARN+L++++ + K+ DFGL++ + E Y G P+ W A
Sbjct 729 RYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTA 788
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE + KF ASD WS+G+ ++E+++ + M+ + +E
Sbjct 789 PEAIAFRKFTSASDAWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIE 834
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ RLP P CP ++ LM +CW+ + + RP F ++ L
Sbjct 835 QDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSAL 874
Score = 80.1 bits (196), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 64/248 (26%), Positives = 110/248 (44%), Gaps = 24/248 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F AS+M Q H ++ + GV +++TE++E+G LD +LR G + + +
Sbjct 661 FLSEASIMGQFEHPNIIRLEGVVTNSVPVMILTEFMENGALDSFLRLNDGQFTVIQLVGM 720
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ +AS + YL + VH ++ RNIL+ ++ K+SD GL E +
Sbjct 721 LRGIASGMRYLAEMSYVHRDLAARNILV-------NSNLVCKVSD--FGLSRFLEENSSD 771
Query 775 ---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+IP W APE + ++A D W +G + E+ GE P S +
Sbjct 772 PTYTSSLGGKIPIRWTAPEAI--AFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDV 829
Query 824 EHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
+ ++ +RL P P CP L L C + RP F ++ L ++ + + +
Sbjct 830 INAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVAR 889
Query 882 PDSPASDP 889
+ AS P
Sbjct 890 ENGGASHP 897
>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase
kinase 3 OS=Homo sapiens OX=9606 GN=MAP3K3 PE=1 SV=2
Length=626
Score = 123 bits (308), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 73/200 (37%), Positives = 114/200 (57%), Gaps = 11/200 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP----QHRSGWKQEIDILRTLYHEH 958
LG+G FG+V L CYD TG +A K ++ D + S + EI +L+ L HE
Sbjct 368 LGQGAFGRVYL-CYDVD---TGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHER 423
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQ 1017
I++Y GC D+ EK+L + MEY+P GS++D L + ++ + + +QI EGM+YLH+
Sbjct 424 IVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSN 483
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRD+ N+L D+ VK+GDFG +K + +R +P +W +PE +
Sbjct 484 MIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTP-YWMSPEVISGE 542
Query 1077 KFYYASDVWSFGVTLYELLT 1096
+ +DVWS G T+ E+LT
Sbjct 543 GYGRKADVWSLGCTVVEMLT 562
Score = 37.4 bits (85), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 62/257 (24%), Positives = 98/257 (38%), Gaps = 47/257 (18%)
Query 632 DRGQELRVVLKVLDPSHHDIAL---AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT- 687
D G+EL DP + + A L+ + H + +G C+R +T
Sbjct 383 DTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYG-CLRDRAEKTLTI 441
Query 688 --EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
EY+ G + L+ G + + +Q+ +SYL + +VH ++ G NIL
Sbjct 442 FMEYMPGGSVKDQLK-AYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSA 500
Query 746 GLAEGTSPFIKLSDPGV----------GLGALSREERVERIP-WLAPECLPGGANSLSTA 794
G +KL D G G G S V P W++PE + G
Sbjct 501 G-------NVKLGDFGASKRLQTICMSGTGMRS----VTGTPYWMSPEVISG--EGYGRK 547
Query 795 MDKWGFGATLLEICFDGEAPLQSRSP-SEKEHFYQRQHRLPEPSCPQLATLTSQC----- 848
D W G T++E+ L + P +E E +P+ PQL + S+
Sbjct 548 ADVWSLGCTVVEM-------LTEKPPWAEYEAMAAIFKIATQPTNPQLPSHISEHGRDFL 600
Query 849 --LTYEPTQRPSFRTIL 863
+ E QRPS +L
Sbjct 601 RRIFVEARQRPSAEELL 617
>sp|Q00993|UFO_MOUSE Tyrosine-protein kinase receptor UFO OS=Mus
musculus OX=10090 GN=Axl PE=1 SV=2
Length=888
Score = 124 bits (311), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 91/285 (32%), Positives = 134/285 (47%), Gaps = 31/285 (11%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDIL 951
HK L K LGEG FG V + D + VAVK +K A C + E +
Sbjct 528 HKVALGKT--LGEGEFGAVMEGQLN--QDDSILKVAVKTMKIAICTRSELEDFLSEAVCM 583
Query 952 RTLYHEHIIKYKGCC----EDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-------LAQL 1000
+ H ++++ G C + +G +++ ++ G L +L +G L
Sbjct 584 KEFDHPNVMRLIGVCFQGSDREGFPEPVVILPFMKHGDLHSFLLYSRLGDQPVFLPTQML 643
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+ F I GM YL + +IHRDLAARN +L+ + V + DFGL+K + G +YYR
Sbjct 644 VKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNG-DYYRQGRI 702
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
PV W A E L + + SDVWSFGVT++E+ T Q+P G+ +
Sbjct 703 AKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATR---GQTP------YPGVENSE-- 751
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + L +G RL +P C +Y LM CWE RP+F L
Sbjct 752 ---IYDYLRQGNRLKQPVDCLDGLYALMSRCWELNPRDRPSFAEL 793
Score = 76.3 bits (186), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 87/320 (27%), Positives = 139/320 (43%), Gaps = 55/320 (17%)
Query 600 RTNVYEGRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA---- 654
R V G+ EG G EG+++ +D + L+V +K + IA+
Sbjct 527 RHKVALGKTLGEGEFGAVMEGQLNQDDSI---------LKVAVKTMK-----IAICTRSE 572
Query 655 ---FYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEYVEHGPLDVWLRRER-G 704
F A M + H ++ + GVC +G PE +++ +++HG L +L R G
Sbjct 573 LEDFLSEAVCMKEFDHPNVMRLIGVCFQGSDREGFPEPVVILPFMKHGDLHSFLLYSRLG 632
Query 705 HVP--MAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
P + +M+V +AS + YL K +H ++ RN +L E S + ++D
Sbjct 633 DQPVFLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLN-----ENMS--VCVADF 685
Query 761 GVGL----GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ G R+ R+ ++P W+A E L ++ D W FG T+ EI G+ P
Sbjct 686 GLSKKIYNGDYYRQGRIAKMPVKWIAIESL--ADRVYTSKSDVWSFGVTMWEIATRGQTP 743
Query 815 LQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTR---- 868
SE + ++ +RL +P L L S+C P RPSF + DL
Sbjct 744 YPGVENSEIYDYLRQGNRLKQPVDCLDGLYALMSRCWELNPRDRPSFAELREDLENTLKA 803
Query 869 LQPHNLAD-VLTVNPDSPAS 887
L P D +L VN D S
Sbjct 804 LPPAQEPDEILYVNMDEGGS 823
>sp|P34925|RYK_HUMAN Tyrosine-protein kinase RYK OS=Homo sapiens
OX=9606 GN=RYK PE=1 SV=3
Length=607
Score = 122 bits (307), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 95/317 (30%), Positives = 155/317 (49%), Gaps = 29/317 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRY-LKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926
R++ ++L V + D + +R LK + L EG FG++ D E
Sbjct 302 RIEKNDLRSVTLLEAKGKVKDIAISRERITLKDV--LQEGTFGRIFHGILIDEKDPNKEK 359
Query 927 VA-VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
A VK +K + E LR L+H +++ C ++GEK + +++ Y+ G+
Sbjct 360 QAFVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPM-VILPYMNWGN 418
Query 986 LRDYLPR---------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036
L+ +L + +I L+ A QI GM+YL + IH+DLAARN ++D+
Sbjct 419 LKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTLQ 478
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
VKI D L++ + +Y+ + ++ + PV W A E L +F ASDVW+FGVTL+EL+T
Sbjct 479 VKITDNALSRDLFP-MDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMT 537
Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156
Q+P + I +M L+ G R+ +P CP E++ +M CW +
Sbjct 538 ---LGQTP------YVDIDPFEMAA-----YLKDGYRIAQPINCPDELFAVMACCWALDP 583
Query 1157 SFRPTFENLIPILKTVH 1173
RP F+ L+ L H
Sbjct 584 EERPKFQQLVQCLTEFH 600
Score = 74.3 bits (181), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 72/312 (23%), Positives = 144/312 (46%), Gaps = 39/312 (13%)
Query 583 RVDQKEITQLSHL-GQGTRTNVYEGRLRVEGSGDPEEGKMDD--EDPLVPGRDRGQELRV 639
R+++ ++ ++ L +G ++ R R+ +EG L+ +D +E +
Sbjct 302 RIEKNDLRSVTLLEAKGKVKDIAISRERITLKDVLQEGTFGRIFHGILIDEKDPNKEKQA 361
Query 640 VLKVLDPSHHDIALAFYETASL-MSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDV 697
+K + +I + T S + + H +L + VC+ G + +++ Y+ G L +
Sbjct 362 FVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKL 421
Query 698 WLRRER---GHVPMAWK----MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
+LR+ + + P A + +A Q+A +SYL + ++H ++ RN ++
Sbjct 422 FLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVI-------D 474
Query 751 TSPFIKLSDPGVGLGALSRE----------ERVER-IPWLAPECLPGGANSLSTAMDKWG 799
+ +K++D ALSR+ + R + W+A E L N S+A D W
Sbjct 475 DTLQVKITD-----NALSRDLFPMDYHCLGDNENRPVRWMALESLVN--NEFSSASDVWA 527
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRP 857
FG TL E+ G+ P P E + + +R+ +P +CP +L + + C +P +RP
Sbjct 528 FGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERP 587
Query 858 SFRTILRDLTRL 869
F+ +++ LT
Sbjct 588 KFQQLVQCLTEF 599
>sp|Q07497|EPHB5_CHICK Ephrin type-B receptor 5 OS=Gallus gallus
OX=9031 GN=EPHB5 PE=2 SV=1
Length=1002
Score = 124 bits (311), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 80/286 (28%), Positives = 144/286 (50%), Gaps = 25/286 (9%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDP-TNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRT 953
++K +G G FG+V C+ + G E VA+K LK+ + R + E I+
Sbjct 636 FIKIEEVIGSGEFGEV---CFGRLKHPGKREYTVAIKTLKSGYTDEQRREFLSEASIMGQ 692
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGM 1011
H ++I +G + + +V E++ GSL +L + + QL+ + I GM
Sbjct 693 FEHPNVIHLEGVVTKS--RPVMIVTEFMENGSLDSFLRQKEGQFSVLQLVGMLRGIAAGM 750
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE--GHEYYRVREDGDSPVFWYA 1069
YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + + Y P+ W A
Sbjct 751 RYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDASNPTYTGALGCKIPIRWTA 810
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE ++ KF +SDVWS+G+ ++E++++ + M+ + ++
Sbjct 811 PEAVQYRKFTSSSDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVINAID 856
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+ RLP P CP ++ LM +CW+ + RP FE ++ L + K
Sbjct 857 QDYRLPPPPDCPTVLHLLMLDCWQKDRVQRPKFEQIVSALDKMIRK 902
Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 72/252 (29%), Positives = 121/252 (48%), Gaps = 22/252 (9%)
Query 629 PGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
PG+ +E V +K L + D F AS+M Q H ++ + GV + ++VT
Sbjct 659 PGK---REYTVAIKTLKSGYTDEQRREFLSEASIMGQFEHPNVIHLEGVVTKSRPVMIVT 715
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
E++E+G LD +LR++ G + + + + +A+ + YL + N VH ++ RNIL+ +
Sbjct 716 EFMENGSLDSFLRQKEGQFSVLQLVGMLRGIAAGMRYLSDMNYVHRDLAARNILVNSNLV 775
Query 748 AE----GTSPFIK--LSDPGVGLGALSREERVERIP--WLAPECLPGGANSLSTAMDKWG 799
+ G S F++ S+P GAL +IP W APE + +++ D W
Sbjct 776 CKVSDFGLSRFLEDDASNPTY-TGALGC-----KIPIRWTAPEAVQ--YRKFTSSSDVWS 827
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQRP 857
+G + E+ GE P S + + + +RL P P CP L L C + QRP
Sbjct 828 YGIVMWEVMSYGERPYWDMSNQDVINAIDQDYRLPPPPDCPTVLHLLMLDCWQKDRVQRP 887
Query 858 SFRTILRDLTRL 869
F I+ L ++
Sbjct 888 KFEQIVSALDKM 899
>sp|Q9UM73|ALK_HUMAN ALK tyrosine kinase receptor OS=Homo sapiens
OX=9606 GN=ALK PE=1 SV=3
Length=1620
Score = 124 bits (312), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 104/350 (30%), Positives = 153/350 (44%), Gaps = 46/350 (13%)
Query 855 QRPSFR-TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV-S 912
Q P ++ + LR T + +N + S SD ++ + IR LG G FG+V
Sbjct 1074 QSPEYKLSKLRTSTIMTDYN-PNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYE 1132
Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972
ND + VAVK L C Q + E I+ H++I++ G
Sbjct 1133 GQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGV------- 1185
Query 973 SLQ-----LVMEYVPLGSLRDYL----PR----HSIGLAQLLLFAQQICEGMAYLHAQHY 1019
SLQ +++E + G L+ +L PR S+ + LL A+ I G YL H+
Sbjct 1186 SLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHF 1245
Query 1020 IHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+AARN LL R+ KIGDFG+A+ + YYR PV W PE E
Sbjct 1246 IHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRA-SYYRKGGCAMLPVKWMPPEAFMEG 1304
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
F +D WSFGV L+E+ + L + + + E + G R+
Sbjct 1305 IFTSKTDTWSFGVLLWEIFS--------------LGYMPYPSKSNQEVLEFVTSGGRMDP 1350
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
P CP VY +M CW+ + RP F ++ + +Y Q P V +
Sbjct 1351 PKNCPGPVYRIMTQCWQHQPEDRPNFAIILERI-----EYCTQDPDVINT 1395
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 85/310 (27%), Positives = 134/310 (43%), Gaps = 42/310 (14%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
+T ++S L V +K IT + LG G VYEG++ SG P +D PL
Sbjct 1101 KTSSISDL--KEVPRKNITLIRGLGHGAFGEVYEGQV----SGMP-----NDPSPL---- 1145
Query 632 DRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
+V +K L + L F A ++S+ +H ++ GV ++ ++ E +
Sbjct 1146 ------QVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELM 1199
Query 691 EHGPLDVWLR--RERGHVPMAWKMV----VAQQLASALSYLENKNLVHGNVCGRNILLAR 744
G L +LR R R P + M+ VA+ +A YLE + +H ++ RN LL
Sbjct 1200 AGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLT- 1258
Query 745 LGLAEGTSPFIKLSDPGVG----LGALSREERVERIP--WLAPECLPGGANSLSTAMDKW 798
G K+ D G+ + R+ +P W+ PE G ++ D W
Sbjct 1259 ---CPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGI--FTSKTDTW 1313
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQR 856
FG L EI G P S+S E F R+ P +CP + + +QC ++P R
Sbjct 1314 SFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDR 1373
Query 857 PSFRTILRDL 866
P+F IL +
Sbjct 1374 PNFAIILERI 1383
>sp|Q61084|M3K3_MOUSE Mitogen-activated protein kinase kinase
kinase 3 OS=Mus musculus OX=10090 GN=Map3k3 PE=1 SV=1
Length=626
Score = 122 bits (307), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 82/239 (34%), Positives = 127/239 (53%), Gaps = 20/239 (8%)
Query 868 RLQPHNLADVLTVN----PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923
RL+ + + LTV P S P + + L LG+G FG+V L CYD T
Sbjct 334 RLRSADSENALTVQERNVPTKSPSAPINWRRGKL-----LGQGAFGRVYL-CYDV---DT 384
Query 924 GEMVAVKALKADCGP----QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979
G +A K ++ D + S + EI +L+ L HE I++Y GC D+ EK L + ME
Sbjct 385 GRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKILTIFME 444
Query 980 YVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
Y+P GS++D L + ++ + + +QI EGM+YLH+ +HRD+ N+L D+ VK
Sbjct 445 YMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVK 504
Query 1039 IGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+GDFG +K + +R +P +W +PE + + +DVWS G T+ E+LT
Sbjct 505 LGDFGASKRLQTICMSGTGIRSVTGTP-YWMSPEVISGEGYGRKADVWSLGCTVVEMLT 562
Score = 37.7 bits (86), Expect = 0.67, Method: Compositional matrix adjust.
Identities = 47/193 (24%), Positives = 76/193 (39%), Gaps = 32/193 (17%)
Query 632 DRGQELRVVLKVLDPSHHDIAL---AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT- 687
D G+EL DP + + A L+ + H + +G C+R ++T
Sbjct 383 DTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYG-CLRDRAEKILTI 441
Query 688 --EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
EY+ G + L+ G + + +Q+ +SYL + +VH ++ G NIL
Sbjct 442 FMEYMPGGSVKDQLK-AYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSA 500
Query 746 GLAEGTSPFIKLSDPGV----------GLGALSREERVERIP-WLAPECLPGGANSLSTA 794
G +KL D G G G S V P W++PE + G
Sbjct 501 G-------NVKLGDFGASKRLQTICMSGTGIRS----VTGTPYWMSPEVISG--EGYGRK 547
Query 795 MDKWGFGATLLEI 807
D W G T++E+
Sbjct 548 ADVWSLGCTVVEM 560
>sp|P0DV84|ALK_CANLF ALK tyrosine kinase receptor OS=Canis lupus
familiaris OX=9615 GN=ALK PE=3 SV=1
Length=1631
Score = 124 bits (312), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 104/350 (30%), Positives = 153/350 (44%), Gaps = 46/350 (13%)
Query 855 QRPSFR-TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV-S 912
Q P ++ + LR T + +N + S SD ++ + IR LG G FG+V
Sbjct 1089 QSPEYKLSKLRTSTIMTDYN-PNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYE 1147
Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972
+D + VAVK L C Q + E I+ H++I++ G
Sbjct 1148 GQVSGVPSDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGV------- 1200
Query 973 SLQ-----LVMEYVPLGSLRDYL----PR----HSIGLAQLLLFAQQICEGMAYLHAQHY 1019
SLQ +++E + G L+ +L PR S+ + LL AQ I G YL H+
Sbjct 1201 SLQALPRFILLELMAGGDLKSFLRETRPRPNQPSSLAMLDLLHVAQDIACGCQYLEENHF 1260
Query 1020 IHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+AARN LL R+ KIGDFG+A+ + YYR PV W PE E
Sbjct 1261 IHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRA-SYYRKGGCAMLPVKWMPPEAFMEG 1319
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
F +D WSFGV L+E+ + L + + + E + G R+
Sbjct 1320 IFTSKTDTWSFGVLLWEIFS--------------LGYMPYPSKSNQEVLEFVTSGGRMDP 1365
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
P CP VY +M CW+ + RP F ++ + +Y Q P V +
Sbjct 1366 PKNCPGPVYRIMTQCWQHQPEDRPNFAIILERI-----EYCTQDPDVINT 1410
Score = 84.0 bits (206), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 86/310 (28%), Positives = 134/310 (43%), Gaps = 42/310 (14%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
+T ++S L V +K IT + LG G VYEG++ SG P D PL
Sbjct 1116 KTSSISDLK--EVPRKNITLIRGLGHGAFGEVYEGQV----SGVP-----SDPSPL---- 1160
Query 632 DRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
+V +K L + L F A ++S+ +H ++ GV ++ ++ E +
Sbjct 1161 ------QVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELM 1214
Query 691 EHGPLDVWLR--RERGHVPMAWKMV----VAQQLASALSYLENKNLVHGNVCGRNILLAR 744
G L +LR R R + P + M+ VAQ +A YLE + +H ++ RN LL
Sbjct 1215 AGGDLKSFLRETRPRPNQPSSLAMLDLLHVAQDIACGCQYLEENHFIHRDIAARNCLLT- 1273
Query 745 LGLAEGTSPFIKLSDPGVG----LGALSREERVERIP--WLAPECLPGGANSLSTAMDKW 798
G K+ D G+ + R+ +P W+ PE G ++ D W
Sbjct 1274 ---CPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGI--FTSKTDTW 1328
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQR 856
FG L EI G P S+S E F R+ P +CP + + +QC ++P R
Sbjct 1329 SFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDR 1388
Query 857 PSFRTILRDL 866
P+F IL +
Sbjct 1389 PNFAIILERI 1398
>sp|P80192|M3K9_HUMAN Mitogen-activated protein kinase kinase
kinase 9 OS=Homo sapiens OX=9606 GN=MAP3K9 PE=1 SV=3
Length=1104
Score = 124 bits (311), Expect = 3e-27, Method: Compositional matrix adjust.
Identities = 99/297 (33%), Positives = 145/297 (49%), Gaps = 43/297 (14%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG---PQHRSGWKQEI 948
F + L++I +G G FGKV + G+ VAVKA + D Q +QE
Sbjct 141 FAELTLEEI--IGIGGFGKVYRAFW------IGDEVAVKAARHDPDEDISQTIENVRQEA 192
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008
+ L H +II +G C E +L LVME+ G L L I L+ +A QI
Sbjct 193 KLFAMLKHPNIIALRGVC--LKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIA 250
Query 1009 EGMAYLHAQHY---IHRDLAARNVLL----DN----DRLVKIGDFGLAKAVPEGHEYYRV 1057
GM YLH + IHRDL + N+L+ +N ++++KI DFGLA+ E H ++
Sbjct 251 RGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLAR---EWHRTTKM 307
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
G W APE ++ F SDVWS+GV L+ELLT P + ++ + +A G
Sbjct 308 SAAGT--YAWMAPEVIRASMFSKGSDVWSYGVLLWELLTG-----EVPFRGIDGLAVAYG 360
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ + +L LP P CP LM++CW + RP+F N++ L T+ E
Sbjct 361 ----VAMNKLA-----LPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNILDQLTTIEE 408
Score = 71.6 bits (174), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 72/254 (28%), Positives = 119/254 (47%), Gaps = 28/254 (11%)
Query 634 GQELRVVLKVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
G E+ V DP DI+ + A L + + H ++ + GVC++ P +V E+
Sbjct 165 GDEVAVKAARHDPDE-DISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFA 223
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV---HGNVCGRNIL-LARLG 746
GPL+ L +R +P + A Q+A ++YL ++ +V H ++ NIL L ++
Sbjct 224 RGGPLNRVLSGKR--IPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVE 281
Query 747 LAEGTSPFIKLSDPGVGLGALSRE-ERVERIP------WLAPECLPGGANSLSTAMDKWG 799
+ ++ +K++D G L+RE R ++ W+APE + A+ S D W
Sbjct 282 NGDLSNKILKITDFG-----LAREWHRTTKMSAAGTYAWMAPEVI--RASMFSKGSDVWS 334
Query 800 FGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQR 856
+G L E+ GE P + + + LP PS CP+ A L C +P R
Sbjct 335 YGVLLWEL-LTGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSR 393
Query 857 PSFRTILRDLTRLQ 870
PSF IL LT ++
Sbjct 394 PSFTNILDQLTTIE 407
>sp|O22558|STY8_ARATH Serine/threonine-protein kinase STY8 OS=Arabidopsis
thaliana OX=3702 GN=STY8 PE=1 SV=2
Length=546
Score = 120 bits (302), Expect = 5e-27, Method: Compositional matrix adjust.
Identities = 83/281 (30%), Positives = 139/281 (49%), Gaps = 33/281 (12%)
Query 897 LKKIRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRT 953
LK + + G +G + YC + VA+K LK D + + QE+ I+R
Sbjct 286 LKIEKKVASGSYGDLHRGTYC--------SQEVAIKFLKPDRVNNEMLREFSQEVFIMRK 337
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGM 1011
+ H++++++ G C +L +V E++ GS+ D+L + + L LL A + +GM
Sbjct 338 VRHKNVVQFLGAC--TRSPTLCIVTEFMARGSIYDFLHKQKCAFKLQTLLKVALDVAKGM 395
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
+YLH + IHRDL N+L+D LVK+ DFG+A+ E V W APE
Sbjct 396 SYLHQNNIIHRDLKTANLLMDEHGLVKVADFGVARVQIESG----VMTAETGTYRWMAPE 451
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
++ + + +DV+S+ + L+ELLT P FL + A G ++++G
Sbjct 452 VIEHKPYNHKADVFSYAIVLWELLTG-----DIPYAFLTPLQAAVG---------VVQKG 497
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
R P K +V L++ CW + RP FE +I +L+ +
Sbjct 498 LRPKIPKKTHPKVKGLLERCWHQDPEQRPLFEEIIEMLQQI 538
Score = 73.6 bits (179), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 59/241 (24%), Positives = 112/241 (46%), Gaps = 22/241 (9%)
Query 639 VVLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K L P ++++ F + +M +V H ++ G C R P +VTE++ G +
Sbjct 310 VAIKFLKPDRVNNEMLREFSQEVFIMRKVRHKNVVQFLGACTRSPTLCIVTEFMARGSIY 369
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L +++ + + VA +A +SYL N++H ++ N+L+ GL +K
Sbjct 370 DFLHKQKCAFKLQTLLKVALDVAKGMSYLHQNNIIHRDLKTANLLMDEHGL-------VK 422
Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D GV G ++ E R W+APE + + D + + L E+ G
Sbjct 423 VADFGVARVQIESGVMTAETGTYR--WMAPEVIEH--KPYNHKADVFSYAIVLWEL-LTG 477
Query 812 EAPLQSRSPSEKE-HFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ P +P + Q+ R +P+ + P++ L +C +P QRP F I+ L +
Sbjct 478 DIPYAFLTPLQAAVGVVQKGLRPKIPKKTHPKVKGLLERCWHQDPEQRPLFEEIIEMLQQ 537
Query 869 L 869
+
Sbjct 538 I 538
>sp|Q66L42|M3K10_MOUSE Mitogen-activated protein kinase kinase
kinase 10 OS=Mus musculus OX=10090 GN=Map3k10 PE=1 SV=2
Length=940
Score = 122 bits (307), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 100/306 (33%), Positives = 149/306 (49%), Gaps = 47/306 (15%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW-----KQ 946
FH+ L++I +G G FGKV + GE VAVKA + D P+ +Q
Sbjct 95 FHELQLEEI--IGVGGFGKVYRAVW------RGEEVAVKAARLD--PERDPAVTAEQVRQ 144
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006
E + L H +II +G C +L LVMEY G+L L + L+ +A Q
Sbjct 145 EARLFGALQHPNIIALRGAC--LSPPNLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQ 202
Query 1007 ICEGMAYLHAQH---YIHRDLAARNVLL----DN----DRLVKIGDFGLAKAVPEGHEYY 1055
+ GM YLH IHRDL + N+L+ +N D ++KI DFGLA+ E H+
Sbjct 203 VARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAR---EWHKTT 259
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
++ G W APE ++ F +SDVWSFGV L+ELLT P + ++ + +A
Sbjct 260 KMSAAGT--YAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTG-----EVPYREIDALAVA 312
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
G + + +LT LP P CP L++ CW+ + RP F +++ L+ + +
Sbjct 313 YG-VAMNKLT--------LPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKQLEVIEQS 363
Query 1176 YQGQAP 1181
Q P
Sbjct 364 ALFQMP 369
Score = 65.1 bits (157), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 70/250 (28%), Positives = 108/250 (43%), Gaps = 26/250 (10%)
Query 633 RGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
RG+E+ V LDP A + A L + H ++ + G C+ P +V EY
Sbjct 118 RGEEVAVKAARLDPERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSPPNLCLVMEYA 177
Query 691 EHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745
G L L RR HV + W A Q+A ++YL N ++H ++ NIL+
Sbjct 178 RGGALSRVLAGRRVPPHVLVNW----AVQVARGMNYLHNDAPVPIIHRDLKSINILILEA 233
Query 746 ----GLAEGTSPFIKLSDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
LA+ +K++D G+ ++ W+APE + + S + D W
Sbjct 234 IENHNLADTV---LKITDFGLAREWHKTTKMSAAGTYAWMAPEVI--RLSLFSKSSDVWS 288
Query 800 FGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQR 856
FG L E+ GE P + + + LP PS CP+ A L +C +P R
Sbjct 289 FGVLLWEL-LTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGR 347
Query 857 PSFRTILRDL 866
P F +IL+ L
Sbjct 348 PDFGSILKQL 357
>sp|P04048|KIT_FSVHZ Tyrosine-protein kinase transforming protein
kit OS=Feline sarcoma virus (strain Hardy-Zuckerman 4) OX=11777
GN=V-KIT PE=3 SV=1
Length=370
Score = 117 bits (293), Expect = 6e-27, Method: Compositional matrix adjust.
Identities = 61/173 (35%), Positives = 99/173 (57%), Gaps = 14/173 (8%)
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ +
Sbjct 210 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 268
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
PV W APE + + + SDVWS+G+ L+EL + SS P G
Sbjct 269 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 315
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+ ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++ K
Sbjct 316 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQKNK 368
Score = 50.8 bits (120), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 39/168 (23%), Positives = 74/168 (44%), Gaps = 22/168 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A +++L +KN +H ++ RNILL K+ D G+ + V +
Sbjct 213 QVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIKNDSNYVVKG 265
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--- 827
+ W+APE + + + D W +G L E+ G +P K FY
Sbjct 266 NARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYKMI 321
Query 828 QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
+ R+ PE + ++ + C +P +RP+F+ I++ + + + N
Sbjct 322 KEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQKNKN 369
Score = 37.4 bits (85), Expect = 0.79, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689
+ V +K+L PS H E +LMS++ +H ++ + G C G +++TEY
Sbjct 56 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEY 110
Query 690 VEHGPLDVWLRRER 703
+G L +LRR+R
Sbjct 111 CCYGDLLNFLRRKR 124
>sp|P54753|EPHB3_HUMAN Ephrin type-B receptor 3 OS=Homo sapiens
OX=9606 GN=EPHB3 PE=1 SV=2
Length=998
Score = 122 bits (307), Expect = 7e-27, Method: Compositional matrix adjust.
Identities = 78/273 (29%), Positives = 135/273 (49%), Gaps = 25/273 (9%)
Query 903 LGEGHFGKVSLYCYDPTND-GTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G FG+V C G E+ VA+K LK + R + E I+ H +II
Sbjct 639 IGAGEFGEV---CRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNII 695
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018
+ +G + + ++ E++ +L +L + + QL+ + I GM YL +
Sbjct 696 RLEGVVTKS--RPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMN 753
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE--GHEYYRVREDGDSPVFWYAPECLKEY 1076
Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G P+ W APE +
Sbjct 754 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYR 813
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
KF ASDVWS+G+ ++E++++ + M+ + +E+ RLP
Sbjct 814 KFTSASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVINAVEQDYRLPP 859
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P CP ++ LM +CW + + RP F ++ L
Sbjct 860 PMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTL 892
Score = 83.6 bits (205), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 68/248 (27%), Positives = 115/248 (46%), Gaps = 14/248 (6%)
Query 629 PGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
PGR +E+ V +K L + + F AS+M Q H ++ + GV + +++T
Sbjct 655 PGR---REVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILT 711
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
E++E+ LD +LR G + + + + +A+ + YL N VH ++ RNIL+ +
Sbjct 712 EFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLV 771
Query 748 AE----GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+ G S F++ DP S ++ I W APE + ++A D W +G
Sbjct 772 CKVSDFGLSRFLE-DDPSDPTYTSSLGGKIP-IRWTAPEAI--AYRKFTSASDVWSYGIV 827
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRT 861
+ E+ GE P S + + ++ +RLP P CP L L C + RP F
Sbjct 828 MWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQ 887
Query 862 ILRDLTRL 869
I+ L +L
Sbjct 888 IVNTLDKL 895
>sp|Q08881|ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=Homo sapiens
OX=9606 GN=ITK PE=1 SV=1
Length=620
Score = 121 bits (303), Expect = 7e-27, Method: Compositional matrix adjust.
Identities = 82/280 (29%), Positives = 129/280 (46%), Gaps = 27/280 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L ++++G G FG V L + + VA+K ++ G + +E +++ L H
Sbjct 363 LTFVQEIGSGQFGLVHLGYW-----LNKDKVAIKTIRE--GAMSEEDFIEEAEVMMKLSH 415
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYL 1014
+++ G C +Q + LV E++ G L DYL R LL +CEGMAYL
Sbjct 416 PKLVQLYGVCLEQA--PICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYL 473
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDLAARN L+ ++++K+ DFG+ + V + Y PV W +PE
Sbjct 474 EEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQ--YTSSTGTKFPVKWASPEVFS 531
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
++ SDVWSFGV ++E+ + I + + E + G RL
Sbjct 532 FSRYSSKSDVWSFGVLMWEVFSEGK--------------IPYENRSNSEVVEDISTGFRL 577
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+P VY +M +CW+ RP F L+ L + E
Sbjct 578 YKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAE 617
Score = 90.5 bits (223), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 61/227 (27%), Positives = 104/227 (46%), Gaps = 16/227 (7%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F E A +M ++SH L ++GVC+ +V E++EHG L +LR +RG + +
Sbjct 403 FIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGM 462
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ ++YLE ++H ++ RN L+ G + IK+SD G+ L +
Sbjct 463 CLDVCEGMAYLEEACVIHRDLAARNCLV-------GENQVIKVSDFGMTRFVLDDQYTSS 515
Query 775 R-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
+ W +PE + S+ D W FG + E+ +G+ P ++RS SE
Sbjct 516 TGTKFPVKWASPEVF--SFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDIST 573
Query 830 QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
RL +P + + + + C P RP+F +LR L + L
Sbjct 574 GFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAESGL 620
>sp|Q3U1V8|M3K9_MOUSE Mitogen-activated protein kinase kinase
kinase 9 OS=Mus musculus OX=10090 GN=Map3k9 PE=2 SV=2
Length=1077
Score = 122 bits (306), Expect = 9e-27, Method: Compositional matrix adjust.
Identities = 98/297 (33%), Positives = 145/297 (49%), Gaps = 43/297 (14%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG---PQHRSGWKQEI 948
F + L++I +G G FGKV + G+ VAVKA + D Q +QE
Sbjct 134 FAELTLEEI--IGIGGFGKVYRAFW------AGDEVAVKAARHDPDEDISQTIENVRQEA 185
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008
+ L H +II +G C E +L LVME+ G L L I L+ +A QI
Sbjct 186 KLFAMLKHPNIIALRGVC--LKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIA 243
Query 1009 EGMAYLHAQHY---IHRDLAARNVLL----DN----DRLVKIGDFGLAKAVPEGHEYYRV 1057
GM YLH + IHRDL + N+L+ +N ++++KI DFGLA+ E H ++
Sbjct 244 RGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLAR---EWHRTTKM 300
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
G W APE ++ F SDVWS+GV L+ELLT P + ++ + +A G
Sbjct 301 SAAGT--YAWMAPEVIRASMFSKGSDVWSYGVLLWELLTG-----EVPFRGIDGLAVAYG 353
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ + +L LP P CP LM++CW + RP+F +++ L T+ E
Sbjct 354 ----VAMNKLA-----LPIPSTCPEPFAKLMEDCWNPDPHSRPSFTSILDQLTTIEE 401
Score = 72.0 bits (175), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 72/254 (28%), Positives = 120/254 (47%), Gaps = 28/254 (11%)
Query 634 GQELRVVLKVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
G E+ V DP DI+ + A L + + H ++ + GVC++ P +V E+
Sbjct 158 GDEVAVKAARHDPDE-DISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFA 216
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV---HGNVCGRNIL-LARLG 746
GPL+ L +R +P + A Q+A ++YL ++ +V H ++ NIL L ++
Sbjct 217 RGGPLNRVLSGKR--IPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVE 274
Query 747 LAEGTSPFIKLSDPGVGLGALSRE-ERVERIP------WLAPECLPGGANSLSTAMDKWG 799
+ ++ +K++D G L+RE R ++ W+APE + A+ S D W
Sbjct 275 NGDLSNKILKITDFG-----LAREWHRTTKMSAAGTYAWMAPEVI--RASMFSKGSDVWS 327
Query 800 FGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQR 856
+G L E+ GE P + + + LP PS CP+ A L C +P R
Sbjct 328 YGVLLWEL-LTGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSR 386
Query 857 PSFRTILRDLTRLQ 870
PSF +IL LT ++
Sbjct 387 PSFTSILDQLTTIE 400
>sp|P54754|EPHB3_MOUSE Ephrin type-B receptor 3 OS=Mus musculus
OX=10090 GN=Ephb3 PE=1 SV=2
Length=993
Score = 122 bits (306), Expect = 9e-27, Method: Compositional matrix adjust.
Identities = 75/269 (28%), Positives = 129/269 (48%), Gaps = 25/269 (9%)
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
VA+K LK + R + E I+ H +II+ +G + + ++ E++ +
Sbjct 656 FVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMILTEFMENCA 713
Query 986 LRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
L +L + + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFG
Sbjct 714 LDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFG 773
Query 1044 LAKAVPE--GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
L++ + + Y G P+ W APE + KF ASDVWS+G+ ++E++++ +
Sbjct 774 LSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGER- 832
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
M+ + +E+ RLP P CP ++ LM +CW + + RP
Sbjct 833 -------------PYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPK 879
Query 1162 FENLIPIL-----KTVHEKYQGQAPSVFS 1185
F ++ L K APS S
Sbjct 880 FSQIVNTLDKLIRNAASLKVTASAPSGMS 908
Score = 84.7 bits (208), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 72/269 (27%), Positives = 124/269 (46%), Gaps = 14/269 (5%)
Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+PGR +E+ V +K L + + F AS+M Q H ++ + GV + +++
Sbjct 649 LPGR---REVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIL 705
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TE++E+ LD +LR G + + + + +A+ + YL N VH ++ RNIL+
Sbjct 706 TEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNL 765
Query 747 LAE----GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+ + G S F++ DP S ++ I W APE + ++A D W +G
Sbjct 766 VCKVSDFGLSRFLE-DDPSDPTYTSSLGGKIP-IRWTAPEAI--AYRKFTSASDVWSYGI 821
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFR 860
+ E+ GE P S + + ++ +RLP P CP L L C + RP F
Sbjct 822 VMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFS 881
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDP 889
I+ L +L + + +T + S S P
Sbjct 882 QIVNTLDKLIRNAASLKVTASAPSGMSQP 910
>sp|D3ZG83|M3K10_RAT Mitogen-activated protein kinase kinase kinase
10 OS=Rattus norvegicus OX=10116 GN=Map3k10 PE=1 SV=3
Length=940
Score = 122 bits (305), Expect = 9e-27, Method: Compositional matrix adjust.
Identities = 100/306 (33%), Positives = 149/306 (49%), Gaps = 47/306 (15%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW-----KQ 946
FH+ L++I +G G FGKV + GE VAVKA + D P+ +Q
Sbjct 95 FHELQLEEI--IGVGGFGKVYRALW------RGEEVAVKAARLD--PERDPAVTAEQVRQ 144
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006
E + L H +II +G C +L LVMEY G+L L + L+ +A Q
Sbjct 145 EARLFGALQHPNIIALRGAC--LSPPNLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQ 202
Query 1007 ICEGMAYLHAQH---YIHRDLAARNVLL----DN----DRLVKIGDFGLAKAVPEGHEYY 1055
+ GM YLH IHRDL + N+L+ +N D ++KI DFGLA+ E H+
Sbjct 203 VARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAR---EWHKTT 259
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
++ G W APE ++ F +SDVWSFGV L+ELLT P + ++ + +A
Sbjct 260 KMSAAGT--YAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTG-----EVPYREIDALAVA 312
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
G + + +LT LP P CP L++ CW+ + RP F +++ L+ + +
Sbjct 313 YG-VAMNKLT--------LPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKQLEVIEQS 363
Query 1176 YQGQAP 1181
Q P
Sbjct 364 ALFQMP 369
Score = 65.1 bits (157), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 70/250 (28%), Positives = 108/250 (43%), Gaps = 26/250 (10%)
Query 633 RGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
RG+E+ V LDP A + A L + H ++ + G C+ P +V EY
Sbjct 118 RGEEVAVKAARLDPERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSPPNLCLVMEYA 177
Query 691 EHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745
G L L RR HV + W A Q+A ++YL N ++H ++ NIL+
Sbjct 178 RGGALSRVLAGRRVPPHVLVNW----AVQVARGMNYLHNDAPVPIIHRDLKSINILILEA 233
Query 746 ----GLAEGTSPFIKLSDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
LA+ +K++D G+ ++ W+APE + + S + D W
Sbjct 234 IENHNLADTV---LKITDFGLAREWHKTTKMSAAGTYAWMAPEVI--RLSLFSKSSDVWS 288
Query 800 FGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQR 856
FG L E+ GE P + + + LP PS CP+ A L +C +P R
Sbjct 289 FGVLLWEL-LTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGR 347
Query 857 PSFRTILRDL 866
P F +IL+ L
Sbjct 348 PDFGSILKQL 357
>sp|Q07498|EPHB3_CHICK Ephrin type-B receptor 3 (Fragment) OS=Gallus
gallus OX=9031 GN=EPHB3 PE=2 SV=1
Length=988
Score = 122 bits (305), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 78/273 (29%), Positives = 134/273 (49%), Gaps = 25/273 (9%)
Query 903 LGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G FG+V C G E+ VA+K LK + R + E I+ H +II
Sbjct 629 IGAGEFGEV---CRGRLKLPGRREIFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNII 685
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018
+G + + ++ E++ +L +L + + QL+ + I GM YL +
Sbjct 686 HLEGVVTKS--RPVMIITEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMN 743
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE--GHEYYRVREDGDSPVFWYAPECLKEY 1076
Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G P+ W APE +
Sbjct 744 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPADPTYTSSLGGKIPIRWTAPEAIAYR 803
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
KF ASDVWS+G+ ++E++++ + M+ + +E+ RLP
Sbjct 804 KFTSASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVINAVEQDYRLPP 849
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P CP ++ LM +CW + + RP F ++ L
Sbjct 850 PMDCPTALHQLMLDCWVRDRNLRPKFAQIVNTL 882
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 68/249 (27%), Positives = 116/249 (47%), Gaps = 14/249 (6%)
Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+PGR +E+ V +K L + + F AS+M Q H ++ + GV + +++
Sbjct 644 LPGR---REIFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIHLEGVVTKSRPVMII 700
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TE++E+ LD +LR G + + + + +A+ + YL N VH ++ RNIL+
Sbjct 701 TEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNL 760
Query 747 LAE----GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+ + G S F++ DP S ++ I W APE + ++A D W +G
Sbjct 761 VCKVSDFGLSRFLE-DDPADPTYTSSLGGKIP-IRWTAPEAI--AYRKFTSASDVWSYGI 816
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFR 860
+ E+ GE P S + + ++ +RLP P CP L L C + RP F
Sbjct 817 VMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFA 876
Query 861 TILRDLTRL 869
I+ L +L
Sbjct 877 QIVNTLDKL 885
>sp|Q21038|VER3_CAEEL Tyrosine-protein kinase receptor ver-3 OS=Caenorhabditis
elegans OX=6239 GN=ver-3 PE=2 SV=1
Length=1227
Score = 122 bits (305), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 66/176 (38%), Positives = 91/176 (52%), Gaps = 17/176 (10%)
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ LL QI +GMA+L +HRDLA RNVL+ ++V+I DFGL+K YYR
Sbjct 1005 SDLLSIGLQIAKGMAWLADVPCVHRDLACRNVLITKTKIVRIADFGLSKK-HTNKTYYRT 1063
Query 1058 REDGDS--PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
++ D+ PV W EC++E+KF SDVWSFG+ LYE+ T L G
Sbjct 1064 KKSKDTPLPVRWMPLECIEEFKFTQKSDVWSFGICLYEIFT--------------LGGTP 1109
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ E + G R +P+ C E+Y LMK CW+ RPTF + I +
Sbjct 1110 YPNCDTFNVIEFIRNGNRNKQPEYCHDEIYELMKVCWQFNPKDRPTFNDCITFFEN 1165
Score = 42.0 bits (97), Expect = 0.039, Method: Compositional matrix adjust.
Identities = 34/159 (21%), Positives = 67/159 (42%), Gaps = 19/159 (12%)
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--- 768
+ + Q+A +++L + VH ++ RN+L+ + + ++++D G+ +
Sbjct 1008 LSIGLQIAKGMAWLADVPCVHRDLACRNVLITK-------TKIVRIADFGLSKKHTNKTY 1060
Query 769 -REERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
R ++ + P W+ EC+ + D W FG L EI G P +
Sbjct 1061 YRTKKSKDTPLPVRWMPLECIEEF--KFTQKSDVWSFGICLYEIFTLGGTPYPNCDTFNV 1118
Query 824 EHFYQRQHRLPEPS-C-PQLATLTSQCLTYEPTQRPSFR 860
F + +R +P C ++ L C + P RP+F
Sbjct 1119 IEFIRNGNRNKQPEYCHDEIYELMKVCWQFNPKDRPTFN 1157
>sp|Q17833|OLD1_CAEEL Tyrosine-protein kinase receptor old-1 OS=Caenorhabditis
elegans OX=6239 GN=old-1 PE=2 SV=3
Length=502
Score = 119 bits (297), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 79/228 (35%), Positives = 117/228 (51%), Gaps = 29/228 (13%)
Query 970 GEKSLQLVMEYVPLGSLRDYL----------------PRHSIGLAQLLLFAQQICEGMAY 1013
GE+ + +V E+V G L +L + S+ L LL FA QI +GM Y
Sbjct 253 GERKM-IVSEFVENGDLLSFLRDNRIYFTNDQWTLETEQDSLSLVDLLSFAFQIAKGMEY 311
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE-DGDSPVFWYAPEC 1072
L +HRDLA RNVL+ +R+++I DFGLA+ + +YY+ + D P+ W APE
Sbjct 312 LIHVPCVHRDLALRNVLIKKNRIIRIADFGLARR-HKNKDYYKTQSVDTPLPIHWMAPES 370
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + F SDVWS+GV LYEL + +SP + +I Q + L G+
Sbjct 371 IDKLLFTQKSDVWSYGVCLYELFS---LGKSP---YENVIKYDQRDFYWKYVLSYLNEGK 424
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI----LKTVHEKY 1176
RL +P E+Y++MK CW+ + + R TF + I LKT +Y
Sbjct 425 RLAQPAHADAEIYNVMKLCWDLDMNSRTTFLDCIEFFEKELKTTSNEY 472
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 49/221 (22%), Positives = 95/221 (43%), Gaps = 41/221 (19%)
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM-AWKMVVAQ------------ 716
LA V G+ G ++V+E+VE+G L +LR R + W + Q
Sbjct 244 LALVGGITF-GERKMIVSEFVENGDLLSFLRDNRIYFTNDQWTLETEQDSLSLVDLLSFA 302
Query 717 -QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE----E 771
Q+A + YL + VH ++ RN+L+ + + I+++D G+ +++ +
Sbjct 303 FQIAKGMEYLIHVPCVHRDLALRNVLIKK-------NRIIRIADFGLARRHKNKDYYKTQ 355
Query 772 RVER---IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
V+ I W+APE + + D W +G L E+ G++P ++ ++ FY
Sbjct 356 SVDTPLPIHWMAPESIDKLL--FTQKSDVWSYGVCLYELFSLGKSPYENVIKYDQRDFYW 413
Query 829 RQ--------HRLPEP--SCPQLATLTSQCLTYEPTQRPSF 859
+ RL +P + ++ + C + R +F
Sbjct 414 KYVLSYLNEGKRLAQPAHADAEIYNVMKLCWDLDMNSRTTF 454
>sp|F4JTP5|STY46_ARATH Serine/threonine-protein kinase STY46 OS=Arabidopsis
thaliana OX=3702 GN=STY46 PE=1 SV=1
Length=575
Score = 119 bits (299), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 81/283 (29%), Positives = 142/283 (50%), Gaps = 33/283 (12%)
Query 895 RYLKKIRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDIL 951
++LK + G +G + YC + VA+K LK + + QE+ I+
Sbjct 288 KHLKFGHKIASGSYGDLYKGTYC--------SQEVAIKVLKPERLDSDLEKEFAQEVFIM 339
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICE 1009
R + H++++++ G C L +V E++P GS+ DYL + L L A IC+
Sbjct 340 RKVRHKNVVQFIGAC--TKPPHLCIVTEFMPGGSVYDYLHKQKGVFKLPTLFKVAIDICK 397
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
GM+YLH + IHRDL A N+L+D + +VK+ DFG+A+ + E G W A
Sbjct 398 GMSYLHQNNIIHRDLKAANLLMDENEVVKVADFGVARV--KAQTGVMTAETG--TYRWMA 453
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE ++ + + +DV+S+G+ L+ELLT P +++ + A G +++
Sbjct 454 PEVIEHKPYDHKADVFSYGIVLWELLT-----GKLPYEYMTPLQAAVG---------VVQ 499
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+G R P ++ L++ WE +++ RP F +I L+ +
Sbjct 500 KGLRPTIPKNTHPKLAELLERLWEHDSTQRPDFSEIIEQLQEI 542
Score = 75.9 bits (185), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 60/241 (25%), Positives = 110/241 (46%), Gaps = 22/241 (9%)
Query 639 VVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +KVL P D+ F + +M +V H ++ G C + P +VTE++ G +
Sbjct 314 VAIKVLKPERLDSDLEKEFAQEVFIMRKVRHKNVVQFIGACTKPPHLCIVTEFMPGGSVY 373
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L +++G + VA + +SYL N++H ++ N+L+ + +K
Sbjct 374 DYLHKQKGVFKLPTLFKVAIDICKGMSYLHQNNIIHRDLKAANLLM-------DENEVVK 426
Query 757 LSDPGVG-----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D GV G ++ E R W+APE + D + +G L E+ G
Sbjct 427 VADFGVARVKAQTGVMTAETGTYR--WMAPEVIE--HKPYDHKADVFSYGIVLWEL-LTG 481
Query 812 EAPLQSRSPSEKE-HFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ P + +P + Q+ R +P+ + P+LA L + ++ TQRP F I+ L
Sbjct 482 KLPYEYMTPLQAAVGVVQKGLRPTIPKNTHPKLAELLERLWEHDSTQRPDFSEIIEQLQE 541
Query 869 L 869
+
Sbjct 542 I 542
>sp|P34892|KIN16_CAEEL Receptor-like tyrosine-protein kinase kin-16
OS=Caenorhabditis elegans OX=6239 GN=kin-16 PE=2 SV=1
Length=495
Score = 118 bits (296), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 68/184 (37%), Positives = 93/184 (51%), Gaps = 20/184 (11%)
Query 988 DYLPRHSIG---LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
DY+ + S+ + LL F QI GM YL + +HRDLA RNVLL ++ ++I DFG+
Sbjct 283 DYVIKESLDSLTTSDLLSFGLQIANGMQYLASIPMVHRDLALRNVLLKKNKTIRIADFGM 342
Query 1045 AKAVPEGHEYY--RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
A+ E YY + +D PV W +PE KF SDVWSFG+ LYE+ T
Sbjct 343 ART-HENKSYYIPQKTKDAPVPVRWMSPEAFDTMKFTEKSDVWSFGICLYEIFT------ 395
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
L + + R+ E + G R P+P C E+Y LMK CW + RP F
Sbjct 396 --------LGQLPYPDVPSERIYEYMHSGRRCPQPQHCHVELYDLMKLCWHEKPELRPNF 447
Query 1163 ENLI 1166
N +
Sbjct 448 SNCV 451
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 44/157 (28%), Positives = 70/157 (45%), Gaps = 27/157 (17%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI 776
Q+A+ + YL + +VH ++ RN+LL + + I+++D G+ A + E + I
Sbjct 304 QIANGMQYLASIPMVHRDLALRNVLLKK-------NKTIRIADFGM---ARTHENKSYYI 353
Query 777 P-----------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
P W++PE + D W FG L EI G+ P PSE+ +
Sbjct 354 PQKTKDAPVPVRWMSPEAF--DTMKFTEKSDVWSFGICLYEIFTLGQLPYPD-VPSERIY 410
Query 826 FYQRQ-HRLPEPS-C-PQLATLTSQCLTYEPTQRPSF 859
Y R P+P C +L L C +P RP+F
Sbjct 411 EYMHSGRRCPQPQHCHVELYDLMKLCWHEKPELRPNF 447
>sp|Q5XF79|PBL18_ARATH Probable serine/threonine-protein kinase
PBL18 OS=Arabidopsis thaliana OX=3702 GN=PBL18 PE=2 SV=1
Length=387
Score = 116 bits (290), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 95/295 (32%), Positives = 136/295 (46%), Gaps = 32/295 (11%)
Query 895 RYLKKIRDLGEGHFGKV-----SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
R K +GEG FG V P+ G+G +VAVK LK++ G Q W E+
Sbjct 82 RNFKPNSMIGEGGFGCVYKGWIGERSLSPSKPGSGMVVAVKKLKSE-GFQGHKEWLTEVH 140
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQ 1006
L L+H +++K G C +GEK L LV EY+P GSL ++L R I + A
Sbjct 141 YLGRLHHMNLVKLIGYCL-EGEKRL-LVYEYMPKGSLENHLFRRGAEPIPWKTRMKVAFS 198
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G+++LH I+RD A N+LLD D K+ DFGLAKA P G + V
Sbjct 199 AARGLSFLHEAKVIYRDFKASNILLDVDFNAKLSDFGLAKAGPTGDRTH-VTTQVIGTQG 257
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG--------- 1117
+ APE + + SDV+SFGV L ELL+ PT +G+ +
Sbjct 258 YAAPEYIATGRLTSKSDVYSFGVVLLELLS------GRPTLDKSKVGVERNLVDWAIPYL 311
Query 1118 --QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ V R+ + G+ P K C ++ C TE RP +++ L+
Sbjct 312 VDRRKVFRIMDTKLGGQ---YPHKGACAAANIALRCLNTEPKLRPDMADVLSTLQ 363
Score = 55.1 bits (131), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 58/235 (25%), Positives = 97/235 (41%), Gaps = 36/235 (15%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK--MVVAQQLA 719
+ ++ H +L + G C+ G + ++V EY+ G L+ L R RG P+ WK M VA A
Sbjct 142 LGRLHHMNLVKLIGYCLEGEKRLLVYEYMPKGSLENHLFR-RGAEPIPWKTRMKVAFSAA 200
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERV 773
LS+L +++ + NILL KLSD G+ + + + +
Sbjct 201 RGLSFLHEAKVIYRDFKASNILL-------DVDFNAKLSDFGLAKAGPTGDRTHVTTQVI 253
Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-------HF 826
+ APE + G L++ D + FG LLE+ +S+ E+ +
Sbjct 254 GTQGYAAPEYIATG--RLTSKSDVYSFGVVLLELLSGRPTLDKSKVGVERNLVDWAIPYL 311
Query 827 YQRQH-----------RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
R+ + P A + +CL EP RP +L L +L+
Sbjct 312 VDRRKVFRIMDTKLGGQYPHKGACAAANIALRCLNTEPKLRPDMADVLSTLQQLE 366
>sp|Q02779|M3K10_HUMAN Mitogen-activated protein kinase kinase
kinase 10 OS=Homo sapiens OX=9606 GN=MAP3K10 PE=1 SV=3
Length=954
Score = 120 bits (301), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 100/306 (33%), Positives = 148/306 (48%), Gaps = 47/306 (15%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK-----Q 946
FH+ L++I +G G FGKV + GE VAVKA + D P+ Q
Sbjct 95 FHELQLEEI--IGVGGFGKVYRALW------RGEEVAVKAARLD--PEKDPAVTAEQVCQ 144
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006
E + L H +II +G C + L LVMEY G+L L + L+ +A Q
Sbjct 145 EARLFGALQHPNIIALRGACLNP--PHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQ 202
Query 1007 ICEGMAYLHAQH---YIHRDLAARNVLL----DN----DRLVKIGDFGLAKAVPEGHEYY 1055
+ GM YLH IHRDL + N+L+ +N D ++KI DFGLA+ E H+
Sbjct 203 VARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAR---EWHKTT 259
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
++ G W APE ++ F +SDVWSFGV L+ELLT P + ++ + +A
Sbjct 260 KMSAAGT--YAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTG-----EVPYREIDALAVA 312
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
G + + +LT LP P CP L++ CW+ + RP F +++ L+ + +
Sbjct 313 YG-VAMNKLT--------LPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQS 363
Query 1176 YQGQAP 1181
Q P
Sbjct 364 ALFQMP 369
Score = 63.9 bits (154), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 70/254 (28%), Positives = 110/254 (43%), Gaps = 26/254 (10%)
Query 633 RGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
RG+E+ V LDP A + A L + H ++ + G C+ P +V EY
Sbjct 118 RGEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRGACLNPPHLCLVMEYA 177
Query 691 EHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745
G L L RR HV + W A Q+A ++YL N ++H ++ NIL+
Sbjct 178 RGGALSRVLAGRRVPPHVLVNW----AVQVARGMNYLHNDAPVPIIHRDLKSINILILEA 233
Query 746 ----GLAEGTSPFIKLSDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
LA+ +K++D G+ ++ W+APE + + S + D W
Sbjct 234 IENHNLADTV---LKITDFGLAREWHKTTKMSAAGTYAWMAPEVI--RLSLFSKSSDVWS 288
Query 800 FGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQR 856
FG L E+ GE P + + + LP PS CP+ A L +C +P R
Sbjct 289 FGVLLWEL-LTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGR 347
Query 857 PSFRTILRDLTRLQ 870
P F +IL+ L ++
Sbjct 348 PDFGSILKRLEVIE 361
>sp|Q01974|ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor
ROR2 OS=Homo sapiens OX=9606 GN=ROR2 PE=1 SV=2
Length=943
Score = 120 bits (301), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 82/287 (29%), Positives = 130/287 (45%), Gaps = 35/287 (12%)
Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
++ + +LGE FGKV + + P + VA+K LK R ++ E + L
Sbjct 473 VRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQ 532
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ------------ 999
H +++ G ++ L ++ Y G L ++L P +G
Sbjct 533 HPNVVCLLGVVTK--DQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPP 590
Query 1000 -LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
+ QI GM YL + H +H+DLA RNVL+ + VKI D GL + V +YY++
Sbjct 591 DFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREV-YAADYYKLL 649
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
+ P+ W APE + KF SD+WS+GV L+E+ ++ G +
Sbjct 650 GNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSY---------GLQPYCGYSNQD 700
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ E++ + LP PD CP VY LM CW S RP F+++
Sbjct 701 -----VVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDI 742
Score = 57.0 bits (136), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 77/342 (23%), Positives = 136/342 (40%), Gaps = 67/342 (20%)
Query 548 RRCCLPQPGETSNL-IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606
RR + P + + +I + +A + ++LS + F + LG+ VY+G
Sbjct 441 RRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRF----------MEELGEDRFGKVYKG 490
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQV 665
L G+ Q V +K L D + + F A L +++
Sbjct 491 HLFGPAPGE-------------------QTQAVAIKTLKDKAEGPLREEFRHEAMLRARL 531
Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV----------------PMA 709
H ++ + GV + M+ Y HG L +L H P
Sbjct 532 QHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPD 591
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALS 768
+ +VAQ +A+ + YL + ++VH ++ RN+L+ +L +K+SD G+ +
Sbjct 592 FVHLVAQ-IAAGMEYLSSHHVVHKDLATRNVLVYDKLN--------VKISDLGLFREVYA 642
Query 769 RE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ + I W+APE + G S+ + D W +G L E+ G P S +
Sbjct 643 ADYYKLLGNSLLPIRWMAPEAIMYGKFSIDS--DIWSYGVVLWEVFSYGLQPYCGYSNQD 700
Query 823 KEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
+ + LP P CP + L +C P++RP F+ I
Sbjct 701 VVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDI 742
>sp|Q54PX0|Y4251_DICDI Probable serine/threonine-protein kinase
DDB_G0284251 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0284251
PE=3 SV=1
Length=496
Score = 117 bits (292), Expect = 6e-26, Method: Compositional matrix adjust.
Identities = 84/276 (30%), Positives = 137/276 (50%), Gaps = 28/276 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG+V + N TGE VA+K + ++ K E++IL L H +I+K
Sbjct 42 IGRGAFGQV----FKGLNGKTGEFVAIKQIDSNKIDESSLQSVKGEVEILHKLRHNNIVK 97
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-LLFAQQICEGMAYLHAQHYI 1020
G E Q + L ++EYV GSLRD + + +L +++ Q+ +G+AYLH+ I
Sbjct 98 VLGVVEVQAQ--LNFILEYVENGSLRDVIEKFGPLSEELCIIYLYQMLQGLAYLHSNKVI 155
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ A N+L+ + ++K+ DFG+A + + R G +P +W APE ++
Sbjct 156 HRDIKASNILITKEGVIKLADFGVASQI-DSESQLRFSVVG-TP-YWMAPESIEISGCSS 212
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
ASD+WS G T+ ELLT +PP L Q + R+ + P P
Sbjct 213 ASDIWSLGSTMIELLTG-----NPPYYTL------QPMAAMFRIVS----DQHPPFPTDI 257
Query 1141 PCEVYHLMKNCWETEASFRPTFENLI--PILKTVHE 1174
E + ++ + + RPT + L+ PI T+ +
Sbjct 258 SKEFLDYFQQSFKKDPTQRPTAQELLQHPIFFTLQK 293
Score = 60.8 bits (146), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 53/210 (25%), Positives = 95/210 (45%), Gaps = 17/210 (8%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
++ ++ H ++ V GV + + EYVE+G L + + G + ++ Q+
Sbjct 86 ILHKLRHNNIVKVLGVVEVQAQLNFILEYVENGSLRDVIEK-FGPLSEELCIIYLYQMLQ 144
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE---RVERIP 777
L+YL + ++H ++ NIL+ + G+ IKL+D GV S + V P
Sbjct 145 GLAYLHSNKVIHRDIKASNILITKEGV-------IKLADFGVASQIDSESQLRFSVVGTP 197
Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP-SEKEHFYQRQH-RLP 834
W+APE + + S+A D W G+T++E+ G P + P + QH P
Sbjct 198 YWMAPESIE--ISGCSSASDIWSLGSTMIEL-LTGNPPYYTLQPMAAMFRIVSDQHPPFP 254
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ Q +PTQRP+ + +L+
Sbjct 255 TDISKEFLDYFQQSFKKDPTQRPTAQELLQ 284
>sp|Q08156|KIT_CHICK Mast/stem cell growth factor receptor Kit
OS=Gallus gallus OX=9031 GN=KIT PE=2 SV=1
Length=960
Score = 119 bits (298), Expect = 7e-26, Method: Compositional matrix adjust.
Identities = 65/192 (34%), Positives = 110/192 (57%), Gaps = 17/192 (9%)
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
++ + LL F+ Q+ +GM++L +++ IHRDLAARN+LL + R+ KI DFGLA+ +
Sbjct 748 ALDVEDLLSFSYQVAKGMSFLASKNCIHRDLAARNILLTHGRITKICDFGLARDI-RNDS 806
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
Y V+ + PV W APE + + + SDVWS+G+ L+EL + SS P
Sbjct 807 NYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGILLWELFS-LGSSPYP--------- 856
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
G + ++++ G R+ P+ P E+Y +MK+CW+ + RPTF+ I++ +
Sbjct 857 ---GMPVDSKFYKMIKEGYRMFSPECSPPEMYDIMKSCWDADPLQRPTFKQ---IVQLIE 910
Query 1174 EKYQGQAPSVFS 1185
++ AP V++
Sbjct 911 QQLSDNAPRVYA 922
Score = 57.8 bits (138), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 41/161 (25%), Positives = 72/161 (45%), Gaps = 22/161 (14%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ Q+A +S+L +KN +H ++ RNILL K+ D G+ + V
Sbjct 758 SYQVAKGMSFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIRNDSNYVV 810
Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY- 827
+ + W+APE + + + D W +G L E+ G +P K FY
Sbjct 811 KGNARLPVKWMAPESIFNCVYTFES--DVWSYGILLWELFSLGSSPYPGMPVDSK--FYK 866
Query 828 --QRQHRLPEPSC--PQLATLTSQCLTYEPTQRPSFRTILR 864
+ +R+ P C P++ + C +P QRP+F+ I++
Sbjct 867 MIKEGYRMFSPECSPPEMYDIMKSCWDADPLQRPTFKQIVQ 907
Score = 37.0 bits (84), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689
+ V +K+L PS H E +LMS++ +H ++ + G C G +++TEY
Sbjct 604 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHINIVNLLGACTIGGPTLVITEY 658
Query 690 VEHGPLDVWLRRER 703
+G L +LRR+R
Sbjct 659 CCYGDLLNFLRRKR 672
>sp|Q9Z138|ROR2_MOUSE Tyrosine-protein kinase transmembrane receptor
ROR2 OS=Mus musculus OX=10090 GN=Ror2 PE=1 SV=2
Length=944
Score = 119 bits (298), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 81/287 (28%), Positives = 131/287 (46%), Gaps = 35/287 (12%)
Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
++ + +LGE FGKV + + P + VA+K LK R ++QE + L
Sbjct 473 VRFMEELGEDRFGKVYKGHLFGPAPGEPTQAVAIKTLKDKAEGPLREEFRQEAMLRARLQ 532
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ------------ 999
H +I+ G ++ L ++ Y G L ++L P +G
Sbjct 533 HPNIVCLLGVVTK--DQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPP 590
Query 1000 -LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
+ QI GM +L + H +H+DLA RNVL+ + V+I D GL + V +YY++
Sbjct 591 DFVHVVAQIAAGMEFLSSHHVVHKDLATRNVLVYDKLNVRISDLGLFREV-YSADYYKLM 649
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
+ P+ W +PE + KF SD+WS+GV L+E+ ++ G +
Sbjct 650 GNSLLPIRWMSPEAVMYGKFSIDSDIWSYGVVLWEVFSY---------GLQPYCGYSNQD 700
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ E++ + LP PD CP VY LM CW S RP F+++
Sbjct 701 -----VVEMIRSRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDI 742
Score = 60.1 bits (144), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 80/356 (22%), Positives = 143/356 (40%), Gaps = 70/356 (20%)
Query 548 RRCCLPQPGETSNL-IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606
RR + P + + +I + +A + ++LS + F + LG+ VY+G
Sbjct 441 RRQLMASPSQDMEMPLISQHKQAKLKEISLSTVRF----------MEELGEDRFGKVYKG 490
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQV 665
L G+P + V +K L D + + F + A L +++
Sbjct 491 HLFGPAPGEPTQA-------------------VAIKTLKDKAEGPLREEFRQEAMLRARL 531
Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV----------------PMA 709
H ++ + GV + M+ Y HG L +L H P
Sbjct 532 QHPNIVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPD 591
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALS 768
+ VVAQ +A+ + +L + ++VH ++ RN+L+ +L +++SD G+ S
Sbjct 592 FVHVVAQ-IAAGMEFLSSHHVVHKDLATRNVLVYDKLN--------VRISDLGLFREVYS 642
Query 769 RE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ + I W++PE + G S+ + D W +G L E+ G P S +
Sbjct 643 ADYYKLMGNSLLPIRWMSPEAVMYGKFSIDS--DIWSYGVVLWEVFSYGLQPYCGYSNQD 700
Query 823 KEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI---LRDLTRLQPHN 873
+ + LP P CP + L +C P++RP F+ I LR L +N
Sbjct 701 VVEMIRSRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRSWGNLSNYN 756
>sp|Q9V6K3|ROR2_DROME Tyrosine-protein kinase transmembrane receptor
Ror2 OS=Drosophila melanogaster OX=7227 GN=Nrk PE=1 SV=2
Length=724
Score = 117 bits (294), Expect = 1e-25, Method: Compositional matrix adjust.
Identities = 84/282 (30%), Positives = 130/282 (46%), Gaps = 34/282 (12%)
Query 900 IRDLGEGHFGKVSLYCYDP--TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+R LG+G FG+V P D +VAVK LK D Q + +++E +L H
Sbjct 444 VRSLGQGAFGRV-FQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHP 502
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--------------PRHSIGLAQLLLF 1003
+I++ G C + + L+ EY+ G L ++L R + LL
Sbjct 503 NIVRLLGVCALG--RPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQM 560
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
A I GM YL + ++HRDLA RN L++ VKI DFGL+ + +YY+ E+
Sbjct 561 AANIAAGMLYLSERKFVHRDLATRNCLINEHMAVKIADFGLSHKI-YLQDYYKGDENDFI 619
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
P+ W E + KF SDVW++G+ L+E+ + G+ +
Sbjct 620 PIRWMPLESILYNKFSLESDVWAYGICLWEVFSF---------ALQPYFGLTHEE----- 665
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + ++ G L PD P VY LM+ CW + S RP F +
Sbjct 666 VIKYIKEGNVLGCPDNTPLSVYALMRRCWNRKPSERPGFAEI 707
Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 76/324 (23%), Positives = 132/324 (41%), Gaps = 51/324 (16%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
+N+ +G + + R L +L + R D I + LGQG V++ R
Sbjct 416 VTNVSDAKGTKPNAR---LEKLEYPRGD---IVYVRSLGQGAFGRVFQAR---------- 459
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676
LVP + ++L V +K+L D + + + F A L+++ H ++ + GV
Sbjct 460 ------APGLVPDQ---EDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVRLLGV 510
Query 677 CVRGPENIMVTEYVEHGPLDVWLR------------RERGHVPMAWKMVVAQQLASALSY 724
C G ++ EY+ G L +LR ++R + + +A +A+ + Y
Sbjct 511 CALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQMAANIAAGMLY 570
Query 725 LENKNLVHGNVCGRNILLAR---LGLAE-GTSPFIKLSDPGVGLGALSREERVERIPWLA 780
L + VH ++ RN L+ + +A+ G S I L D G E I W+
Sbjct 571 LSERKFVHRDLATRNCLINEHMAVKIADFGLSHKIYLQDYYKG-----DENDFIPIRWMP 625
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840
E + N S D W +G L E+ P + E + + + L P
Sbjct 626 LESIL--YNKFSLESDVWAYGICLWEVFSFALQPYFGLTHEEVIKYIKEGNVLGCPDNTP 683
Query 841 LAT--LTSQCLTYEPTQRPSFRTI 862
L+ L +C +P++RP F I
Sbjct 684 LSVYALMRRCWNRKPSERPGFAEI 707
>sp|O76411|SCD2_CAEEL ALK tyrosine kinase receptor homolog scd-2
OS=Caenorhabditis elegans OX=6239 GN=scd-2 PE=1 SV=3
Length=1421
Score = 118 bits (296), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 83/298 (28%), Positives = 137/298 (46%), Gaps = 47/298 (16%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTL 954
+++ R LG G+FG+V Y +G +AVK + +S + E + T
Sbjct 976 IERGRVLGRGNFGEVYYGEY------SGVKLAVKMISRTFSASQASQSDFCNEALCMGTF 1029
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----------HSIGLAQLLLFA 1004
E++++ G D + + +EY+ G L ++ + ++ L+
Sbjct 1030 VDENVVRLIGI--DFEKVPYMIALEYMEGGDLLSFVKECRPNQVSLNPFQLAMSDLIKIC 1087
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDN---DRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
+ G L Y+HRD+AARN+LL R+ KI DFG+AK + G EYYR+
Sbjct 1088 CDVAAGCKCLETFGYVHRDIAARNILLTTRGPQRVAKIADFGMAKEITYGTEYYRINGRT 1147
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA-----Q 1116
P+ W PE + F SD+WSFGV +E+ + +G+ +
Sbjct 1148 MMPIKWTPPEAFIDGVFTTKSDIWSFGVLCWEVFS---------------LGVVPYPNRR 1192
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ +L LTE G RL P P VY LM++CW+T A+ RP F +++ I + + +
Sbjct 1193 NEEVMLMLTE----GARLEYPYGIPTRVYQLMRDCWKTAAADRPKFVDVVEIFQDIQD 1246
Score = 41.2 bits (95), Expect = 0.084, Method: Compositional matrix adjust.
Identities = 54/229 (24%), Positives = 83/229 (36%), Gaps = 24/229 (10%)
Query 684 IMVTEYVEHGPLDVWLRRERGH--------VPMAWKMVVAQQLASALSYLENKNLVHGNV 735
++ EY+E G L +++ R + + M+ + + +A+ LE VH ++
Sbjct 1048 MIALEYMEGGDLLSFVKECRPNQVSLNPFQLAMSDLIKICCDVAAGCKCLETFGYVHRDI 1107
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE--RVER-----IPWLAPECLPGGA 788
RNILL G K++D G+ E R+ I W PE G
Sbjct 1108 AARNILLT----TRGPQRVAKIADFGMAKEITYGTEYYRINGRTMMPIKWTPPEAFIDGV 1163
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC--PQLATLTS 846
+T D W FG E+ G P +R E RL P ++ L
Sbjct 1164 --FTTKSDIWSFGVLCWEVFSLGVVPYPNRRNEEVMLMLTEGARLEYPYGIPTRVYQLMR 1221
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895
C RP F ++ +Q + A V P PA T H +
Sbjct 1222 DCWKTAAADRPKFVDVVEIFQDIQ-DDPASVGMPFPIHPAVRATFAHSQ 1269
>sp|Q28889|KIT_FELCA Mast/stem cell growth factor receptor Kit
OS=Felis catus OX=9685 GN=KIT PE=2 SV=1
Length=978
Score = 117 bits (294), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%)
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ +
Sbjct 773 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 831
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
PV W APE + + + SDVWS+G+ L+EL + SS P G
Sbjct 832 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 878
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++
Sbjct 879 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 926
Score = 48.9 bits (115), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 38/161 (24%), Positives = 71/161 (44%), Gaps = 22/161 (14%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ Q+A +++L +KN +H ++ RNILL K+ D G+ + V
Sbjct 774 SYQVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIKNDSNYVV 826
Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY- 827
+ + W+APE + + + D W +G L E+ G +P K FY
Sbjct 827 KGNARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYK 882
Query 828 --QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ R+ PE + ++ + C +P +RP+F+ I++
Sbjct 883 MIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQ 923
Score = 37.0 bits (84), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689
+ V +K+L PS H E +LMS++ +H ++ + G C G +++TEY
Sbjct 619 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEY 673
Query 690 VEHGPLDVWLRRER 703
+G L +LRR+R
Sbjct 674 CCYGDLLNFLRRKR 687
>sp|P43481|KIT_BOVIN Mast/stem cell growth factor receptor Kit
OS=Bos taurus OX=9913 GN=KIT PE=2 SV=1
Length=977
Score = 117 bits (294), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%)
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ +
Sbjct 773 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 831
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
PV W APE + + + SDVWS+G+ L+EL + SS P G
Sbjct 832 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 878
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++
Sbjct 879 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 926
Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 44/194 (23%), Positives = 86/194 (44%), Gaps = 28/194 (14%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ Q+A +++L +KN +H ++ RNILL K+ D G+ + V
Sbjct 774 SYQVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIKNDSNYVV 826
Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY- 827
+ + W+APE + + + D W +G L E+ G +P K FY
Sbjct 827 KGNARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYK 882
Query 828 --QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL----RDLTRLQPHNLADVLT 879
+ R+ PE + ++ + C +P +RP+F+ I+ + ++ H +++
Sbjct 883 MIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLAN 942
Query 880 VNP--DSPASDPTV 891
+P ++PA D +V
Sbjct 943 CSPHRENPAVDHSV 956
Score = 36.6 bits (83), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689
+ V +K+L PS H E +LMS++ +H ++ + G C G +++TEY
Sbjct 619 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEY 673
Query 690 VEHGPLDVWLRRER 703
+G L +LRR+R
Sbjct 674 CCYGDLLNFLRRKR 687
>sp|Q28317|KIT_CAPHI Mast/stem cell growth factor receptor Kit
OS=Capra hircus OX=9925 GN=KIT PE=2 SV=1
Length=978
Score = 117 bits (294), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%)
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ +
Sbjct 774 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 832
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
PV W APE + + + SDVWS+G+ L+EL + SS P G
Sbjct 833 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 879
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++
Sbjct 880 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 927
Score = 50.8 bits (120), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 44/194 (23%), Positives = 86/194 (44%), Gaps = 28/194 (14%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ Q+A +++L +KN +H ++ RNILL K+ D G+ + V
Sbjct 775 SYQVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIKNDSNYVV 827
Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY- 827
+ + W+APE + + + D W +G L E+ G +P K FY
Sbjct 828 KGNARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYK 883
Query 828 --QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL----RDLTRLQPHNLADVLT 879
+ R+ PE + ++ + C +P +RP+F+ I+ + ++ H +++
Sbjct 884 MIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLAN 943
Query 880 VNP--DSPASDPTV 891
+P ++PA D +V
Sbjct 944 CSPHRENPAVDHSV 957
Score = 36.6 bits (83), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689
+ V +K+L PS H E +LMS++ +H ++ + G C G +++TEY
Sbjct 619 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEY 673
Query 690 VEHGPLDVWLRRER 703
+G L +LRR+R
Sbjct 674 CCYGDLLNFLRRKR 687
>sp|O97799|KIT_CANLF Mast/stem cell growth factor receptor Kit
OS=Canis lupus familiaris OX=9615 GN=KIT PE=2 SV=2
Length=979
Score = 117 bits (293), Expect = 2e-25, Method: Compositional matrix adjust.
Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%)
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ +
Sbjct 775 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 833
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
PV W APE + + + SDVWS+G+ L+EL + SS P G
Sbjct 834 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 880
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++
Sbjct 881 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 928
Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 48/195 (25%), Positives = 85/195 (44%), Gaps = 30/195 (15%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ Q+A +++L +KN +H ++ RNILL K+ D G+ + V
Sbjct 776 SYQVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIKNDSNYVV 828
Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY- 827
+ + W+APE + + + D W +G L E+ G +P K FY
Sbjct 829 KGNARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYK 884
Query 828 --QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILR-------DLTRLQPHNLAD 876
+ R+ PE + ++ + C +P +RP+F+ I++ D T NLA+
Sbjct 885 MIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISDSTNHIYSNLAN 944
Query 877 VLTVNPDSPASDPTV 891
+ NP+ P D +V
Sbjct 945 C-SPNPERPVVDHSV 958
Score = 36.6 bits (83), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689
+ V +K+L PS H E +LMS++ +H ++ + G C G +++TEY
Sbjct 621 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEY 675
Query 690 VEHGPLDVWLRRER 703
+G L +LRR+R
Sbjct 676 CCYGDLLNFLRRKR 689
>sp|Q2HWD6|KIT_PIG Mast/stem cell growth factor receptor Kit OS=Sus
scrofa OX=9823 GN=KIT PE=2 SV=1
Length=972
Score = 117 bits (293), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%)
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ +
Sbjct 768 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 826
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
PV W APE + + + SDVWS+G+ L+EL + SS P G
Sbjct 827 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 873
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++
Sbjct 874 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 921
Score = 51.2 bits (121), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 44/192 (23%), Positives = 85/192 (44%), Gaps = 28/192 (15%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A +++L +KN +H ++ RNILL K+ D G+ + V +
Sbjct 771 QVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIKNDSNYVVKG 823
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--- 827
+ W+APE + + + D W +G L E+ G +P K FY
Sbjct 824 NARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYKMI 879
Query 828 QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL----RDLTRLQPHNLADVLTVN 881
+ R+ PE + ++ + C +P +RP+F+ I+ + ++ H +++ +
Sbjct 880 KEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCS 939
Query 882 P--DSPASDPTV 891
P ++PA D +V
Sbjct 940 PHRENPAVDHSV 951
Score = 36.6 bits (83), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689
+ V +K+L PS H E +LMS++ +H ++ + G C G +++TEY
Sbjct 614 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEY 668
Query 690 VEHGPLDVWLRRER 703
+G L +LRR+R
Sbjct 669 CCYGDLLNFLRRKR 682
>sp|G4N7X0|MST11_PYRO7 Mitogen-activated protein kinase kinae
kinase MST11 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617
/ FGSC 8958) OX=242507 GN=MST11 PE=1 SV=1
Length=915
Score = 117 bits (293), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 71/211 (34%), Positives = 113/211 (54%), Gaps = 24/211 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRS---------GWKQEIDILR 952
+G+G FG V L + T GE++AVK ++A G ++ K+EI +LR
Sbjct 647 IGQGSFGCVYLALHAIT----GELLAVKQVEAPSPGANSQNDARKKSMIEALKREISLLR 702
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--FAQQICEG 1010
L H +I++Y GC + L + +EYVP GS++ L + L + L+ F +QI G
Sbjct 703 DLRHPNIVQYLGCG--SSAEYLNIFLEYVPGGSVQTMLNSYG-ALPEPLVRSFVRQILNG 759
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-----EGHEYYRVREDGDSPV 1065
++YLH + IHRD+ N+L+DN +KI DFG++K + G + R V
Sbjct 760 LSYLHEREIIHRDIKGANILVDNKGTIKISDFGISKKIEATNLLNGANNNKHRPSLQGSV 819
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
FW APE +K+ + +D+WS G + E++T
Sbjct 820 FWMAPEVVKQTSYTRKADIWSLGCLVVEMMT 850
Score = 43.1 bits (100), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 42/167 (25%), Positives = 70/167 (42%), Gaps = 24/167 (14%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV-TEYVEHGPLDVWLRRERGHVPMAWKM 712
A SL+ + H ++ G C E + + EYV G + L G +P
Sbjct 693 ALKREISLLRDLRHPNIVQYLG-CGSSAEYLNIFLEYVPGGSVQTMLN-SYGALPEPLVR 750
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-------- 764
+Q+ + LSYL + ++H ++ G NIL+ G IK+SD G+
Sbjct 751 SFVRQILNGLSYLHEREIIHRDIKGANILVDNKGT-------IKISDFGISKKIEATNLL 803
Query 765 -GALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
GA + + R + W+APE + S + D W G ++E+
Sbjct 804 NGANNNKHRPSLQGSVFWMAPEVV--KQTSYTRKADIWSLGCLVVEM 848
>sp|P10721|KIT_HUMAN Mast/stem cell growth factor receptor Kit
OS=Homo sapiens OX=9606 GN=KIT PE=1 SV=1
Length=976
Score = 117 bits (293), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%)
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ +
Sbjct 772 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 830
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
PV W APE + + + SDVWS+G+ L+EL + SS P G
Sbjct 831 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 877
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++
Sbjct 878 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 925
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 38/161 (24%), Positives = 71/161 (44%), Gaps = 22/161 (14%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ Q+A +++L +KN +H ++ RNILL K+ D G+ + V
Sbjct 773 SYQVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIKNDSNYVV 825
Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY- 827
+ + W+APE + + + D W +G L E+ G +P K FY
Sbjct 826 KGNARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYK 881
Query 828 --QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ R+ PE + ++ + C +P +RP+F+ I++
Sbjct 882 MIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQ 922
Score = 36.6 bits (83), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689
+ V +K+L PS H E +LMS++ +H ++ + G C G +++TEY
Sbjct 618 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEY 672
Query 690 VEHGPLDVWLRRER 703
+G L +LRR+R
Sbjct 673 CCYGDLLNFLRRKR 686
>sp|Q76II0|KIT_CALJA Mast/stem cell growth factor receptor Kit
OS=Callithrix jacchus OX=9483 GN=KIT PE=2 SV=1
Length=972
Score = 117 bits (293), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%)
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ +
Sbjct 768 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 826
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
PV W APE + + + SDVWS+G+ L+EL + SS P G
Sbjct 827 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 873
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++
Sbjct 874 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 921
Score = 49.3 bits (116), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 38/161 (24%), Positives = 72/161 (45%), Gaps = 22/161 (14%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ Q+A +++L +KN +H ++ RNILL + K+ D G+ + V
Sbjct 769 SYQVAKGMAFLASKNCIHRDLAARNILLTHGRIT-------KICDFGLARDIKNDSNYVV 821
Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY- 827
+ + W+APE + + + D W +G L E+ G +P K FY
Sbjct 822 KGNARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYK 877
Query 828 --QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ R+ PE + ++ + C +P +RP+F+ I++
Sbjct 878 MIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQ 918
Score = 36.6 bits (83), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 30/104 (29%), Positives = 51/104 (49%), Gaps = 19/104 (18%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689
+ V +K+L PS H E +LMS++ +H ++ + G C G +++TEY
Sbjct 614 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEY 668
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHG 733
+G L +LRR+R + ++Q A + L KNL+H
Sbjct 669 CCYGDLLNFLRRKRD------SFICSKQEDHAEAALY-KNLLHS 705
>sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase
kinase 2 OS=Homo sapiens OX=9606 GN=MAP3K2 PE=1 SV=2
Length=619
Score = 115 bits (289), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 69/199 (35%), Positives = 106/199 (53%), Gaps = 9/199 (5%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS----GWKQEIDILRTLYHEH 958
LG+G FG+V L CYD TG +AVK ++ D S + EI +L+ L HE
Sbjct 362 LGQGAFGRVYL-CYDV---DTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHER 417
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL-LFAQQICEGMAYLHAQ 1017
I++Y GC D EK+L + MEY+P GS++D L + + + +QI EG+ YLH+
Sbjct 418 IVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSN 477
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRD+ N+L D+ VK+GDFG +K + + +W +PE +
Sbjct 478 MIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEG 537
Query 1078 FYYASDVWSFGVTLYELLT 1096
+ +D+WS T+ E+LT
Sbjct 538 YGRKADIWSVACTVVEMLT 556
Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 43/192 (22%), Positives = 76/192 (40%), Gaps = 30/192 (16%)
Query 632 DRGQELRVVLKVLDPSHHDIAL---AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
D G+EL V DP + + A L+ + H + +G C+R P+ ++
Sbjct 377 DTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYG-CLRDPQEKTLSI 435
Query 689 YVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
++E+ P + + + + + +Q+ + YL + +VH ++ G NIL G
Sbjct 436 FMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTG 495
Query 747 LAEGTSPFIKLSDPGV----------GLGALSREERVERIP-WLAPECLPGGANSLSTAM 795
+KL D G G G S V P W++PE + G
Sbjct 496 -------NVKLGDFGASKRLQTICLSGTGMKS----VTGTPYWMSPEVISG--EGYGRKA 542
Query 796 DKWGFGATLLEI 807
D W T++E+
Sbjct 543 DIWSVACTVVEM 554
>sp|P05532|KIT_MOUSE Mast/stem cell growth factor receptor Kit
OS=Mus musculus OX=10090 GN=Kit PE=1 SV=3
Length=979
Score = 117 bits (292), Expect = 4e-25, Method: Compositional matrix adjust.
Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%)
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ +
Sbjct 774 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIRNDSNYV-VKGNAR 832
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
PV W APE + + + SDVWS+G+ L+EL + SS P G
Sbjct 833 LPVKWMAPESIFSCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 879
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++
Sbjct 880 KFYKMIKEGFRMVSPEHAPAEMYDVMKTCWDADPLKRPTFKQVVQLIE 927
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 45/188 (24%), Positives = 82/188 (44%), Gaps = 30/188 (16%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A +++L +KN +H ++ RNILL K+ D G+ + V +
Sbjct 777 QVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIRNDSNYVVKG 829
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--- 827
+ W+APE + + + D W +G L E+ G +P K FY
Sbjct 830 NARLPVKWMAPESIFSCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYKMI 885
Query 828 QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILR-------DLTRLQPHNLADVL 878
+ R+ PE + ++ + C +P +RP+F+ +++ D T+ NLA+
Sbjct 886 KEGFRMVSPEHAPAEMYDVMKTCWDADPLKRPTFKQVVQLIEKQISDSTKHIYSNLANC- 944
Query 879 TVNPDSPA 886
NP++P
Sbjct 945 NPNPENPV 952
Score = 37.4 bits (85), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 30/104 (29%), Positives = 51/104 (49%), Gaps = 19/104 (18%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689
+ V +K+L PS H E +LMS++ +H ++ + G C G +++TEY
Sbjct 621 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEY 675
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHG 733
+G L +LRR+R + ++Q A + L KNL+H
Sbjct 676 CCYGDLLNFLRRKRD------SFIFSKQEEQAEAALY-KNLLHS 712
>sp|O61460|VAB1_CAEEL Ephrin receptor 1 OS=Caenorhabditis elegans
OX=6239 GN=vab-1 PE=1 SV=1
Length=1122
Score = 117 bits (292), Expect = 4e-25, Method: Compositional matrix adjust.
Identities = 86/263 (33%), Positives = 123/263 (47%), Gaps = 32/263 (12%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
E VA+K LK+ + ++ + E I+ H ++I+ G + + +V EY+ G
Sbjct 743 ETVAIKTLKSGSSAKAKAEFLTEATIMGQFSHPNVIRLIGVV--TSAEPVMIVAEYMANG 800
Query 985 SLRDYLPR-----HSIGLAQLLLFAQQICEGMAYLHAQHYIHR-----DLAARNVLLDND 1034
SL +L + ++ I GM YL Y+HR DLAARNVLLD +
Sbjct 801 SLDQFLRNTDQRGEKVHWEKITEMLYGIASGMKYLTDMGYVHRVSFLRDLAARNVLLDME 860
Query 1035 RLVKIGDFGLAKAV-PEGH--EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091
KI DFGL++ V EG E G PV W APE + KF +SDVWSFGV +
Sbjct 861 LRCKIADFGLSRGVRSEGSSVEPEYTTNGGKIPVRWTAPEAITHRKFTPSSDVWSFGVVI 920
Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
+E+ C + P + I++ + G RLP P CP +Y + + C
Sbjct 921 WEV---CSFGERPYWDWTNQKVISEVMI-----------GYRLPPPMDCPMGLYRIAQWC 966
Query 1152 WETEASFRPTFENLIPILKTVHE 1174
W+ E RPTF L L T H+
Sbjct 967 WKMERHERPTFTQL---LATFHK 986
Score = 72.0 bits (175), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 72/257 (28%), Positives = 110/257 (43%), Gaps = 34/257 (13%)
Query 639 VVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V +K L A A F A++M Q SH ++ + GV ++V EY+ +G LD
Sbjct 745 VAIKTLKSGSSAKAKAEFLTEATIMGQFSHPNVIRLIGVVTSAEPVMIVAEYMANGSLDQ 804
Query 698 WLRR--ERGHVPMAWKMVVAQ--QLASALSYLENKNLVH-----GNVCGRNILLARLGLA 748
+LR +RG + W+ + +AS + YL + VH ++ RN+LL
Sbjct 805 FLRNTDQRGE-KVHWEKITEMLYGIASGMKYLTDMGYVHRVSFLRDLAARNVLL------ 857
Query 749 EGTSPFIKLSDPGVGLGALSREERVE--------RIP--WLAPECLPGGANSLSTAMDKW 798
K++D G+ G S VE +IP W APE + + + D W
Sbjct 858 -DMELRCKIADFGLSRGVRSEGSSVEPEYTTNGGKIPVRWTAPEAIT--HRKFTPSSDVW 914
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQR 856
FG + E+C GE P + + +RLP P CP L + C E +R
Sbjct 915 SFGVVIWEVCSFGERPYWDWTNQKVISEVMIGYRLPPPMDCPMGLYRIAQWCWKMERHER 974
Query 857 PSFRTILRDLTR--LQP 871
P+F +L + LQP
Sbjct 975 PTFTQLLATFHKYILQP 991
>sp|Q8RWL6|STY17_ARATH Serine/threonine-protein kinase STY17 OS=Arabidopsis
thaliana OX=3702 GN=STY17 PE=1 SV=1
Length=570
Score = 115 bits (287), Expect = 4e-25, Method: Compositional matrix adjust.
Identities = 77/283 (27%), Positives = 140/283 (49%), Gaps = 33/283 (12%)
Query 895 RYLKKIRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDIL 951
+ LK + + G +G++ YC + VA+K LK + + + QE+ I+
Sbjct 290 KQLKIEKKVACGSYGELFRGTYC--------SQEVAIKILKPERVNAEMLREFSQEVYIM 341
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICE 1009
R + H++++++ G C +L +V E++ GS+ D+L +H + LL A + +
Sbjct 342 RKVRHKNVVQFIGAC--TRSPNLCIVTEFMTRGSIYDFLHKHKGVFKIQSLLKVALDVSK 399
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
GM YLH + IHRDL N+L+D +VK+ DFG+A+ E V W A
Sbjct 400 GMNYLHQNNIIHRDLKTANLLMDEHEVVKVADFGVARVQTESG----VMTAETGTYRWMA 455
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE ++ + + +DV+S+ + L+ELLT P +L + A G +++
Sbjct 456 PEVIEHKPYDHRADVFSYAIVLWELLT-----GELPYSYLTPLQAAVG---------VVQ 501
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+G R P + ++ L++ CW+ + + RP F +I +L +
Sbjct 502 KGLRPKIPKETHPKLTELLEKCWQQDPALRPNFAEIIEMLNQL 544
Score = 73.2 bits (178), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 58/241 (24%), Positives = 108/241 (45%), Gaps = 22/241 (9%)
Query 639 VVLKVLDPSHHDIAL--AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K+L P + + F + +M +V H ++ G C R P +VTE++ G +
Sbjct 316 VAIKILKPERVNAEMLREFSQEVYIMRKVRHKNVVQFIGACTRSPNLCIVTEFMTRGSIY 375
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L + +G + + VA ++ ++YL N++H ++ N+L+ +K
Sbjct 376 DFLHKHKGVFKIQSLLKVALDVSKGMNYLHQNNIIHRDLKTANLLM-------DEHEVVK 428
Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D GV G ++ E R W+APE + D + + L E+ G
Sbjct 429 VADFGVARVQTESGVMTAETGTYR--WMAPEVIE--HKPYDHRADVFSYAIVLWEL-LTG 483
Query 812 EAPLQSRSPSEKE-HFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
E P +P + Q+ R +P+ + P+L L +C +P RP+F I+ L +
Sbjct 484 ELPYSYLTPLQAAVGVVQKGLRPKIPKETHPKLTELLEKCWQQDPALRPNFAEIIEMLNQ 543
Query 869 L 869
L
Sbjct 544 L 544
>sp|F8W3R9|ALK_DANRE ALK tyrosine kinase receptor OS=Danio rerio
OX=7955 GN=alk PE=2 SV=2
Length=1705
Score = 117 bits (292), Expect = 5e-25, Method: Compositional matrix adjust.
Identities = 91/294 (31%), Positives = 130/294 (44%), Gaps = 47/294 (16%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGT-GE----MVAVKALKADCGPQHRSGWKQEI 948
+R + R LG G FG+V Y+ G GE VAVK L C Q + E
Sbjct 1110 RRNISLTRGLGHGAFGEV----YEGLAVGIPGEPSPMQVAVKTLPEVCSEQDELDFLMEA 1165
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQ-----LVMEYVPLGSLRDYL----PR----HSI 995
I+ H++I++ G SLQ +++E + G L+ +L PR S+
Sbjct 1166 LIISKFSHQNIVRCIGV-------SLQALPHFILLELMAGGDLKSFLRETRPRLEHPSSL 1218
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGH 1052
+ LL A+ I G YL +IHRD+AARN LL R+ KIGDFG+A+ +
Sbjct 1219 TMVDLLNIARDIARGCQYLEENQFIHRDIAARNCLLTCKGPGRVAKIGDFGMARDIYRA- 1277
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
YYR PV W PE E F +D WSFGV L+E+ + L
Sbjct 1278 SYYRKGGRAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFS--------------LG 1323
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ + + E + G R+ P CP VY +M W+ + RP F ++
Sbjct 1324 YMPYPSRSNQEVLEFVTNGGRMDPPKNCPGPVYRIMTQSWQHQPEDRPNFSTIL 1377
Score = 77.4 bits (189), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 79/301 (26%), Positives = 125/301 (42%), Gaps = 40/301 (13%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
V ++ I+ LG G VYEG L V G+P ++V
Sbjct 1105 LKEVPRRNISLTRGLGHGAFGEVYEG-LAVGIPGEPSP------------------MQVA 1145
Query 641 LKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+K L + L F A ++S+ SH ++ GV ++ + ++ E + G L +L
Sbjct 1146 VKTLPEVCSEQDELDFLMEALIISKFSHQNIVRCIGVSLQALPHFILLELMAGGDLKSFL 1205
Query 700 RRERGHV--PMAWKMV----VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
R R + P + MV +A+ +A YLE +H ++ RN LL +G
Sbjct 1206 RETRPRLEHPSSLTMVDLLNIARDIARGCQYLEENQFIHRDIAARNCLLT----CKGPGR 1261
Query 754 FIKLSDPGVGL----GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
K+ D G+ + R+ +P W+ PE G ++ D W FG L EI
Sbjct 1262 VAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPPEAFMEGI--FTSKTDTWSFGVLLWEI 1319
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILRD 865
G P SRS E F R+ P +CP + + +Q ++P RP+F TIL
Sbjct 1320 FSLGYMPYPSRSNQEVLEFVTNGGRMDPPKNCPGPVYRIMTQSWQHQPEDRPNFSTILER 1379
Query 866 L 866
+
Sbjct 1380 I 1380
>sp|P00545|KFMS_FSVMD Tyrosine-protein kinase transforming protein
fms OS=Feline sarcoma virus (strain McDonough) OX=11778
GN=V-FMS PE=1 SV=2
Length=978
Score = 116 bits (291), Expect = 5e-25, Method: Compositional matrix adjust.
Identities = 61/176 (35%), Positives = 101/176 (57%), Gaps = 18/176 (10%)
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
L LL F+ Q+ +GMA+L +++ IHRD+AARNVLL + R+ KIGDFGLA+ + Y
Sbjct 784 LRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGRVAKIGDFGLARDIMNDSNYI- 842
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA- 1115
V+ + PV W APE + + + SDVWS+G+ L+E+ + +G+
Sbjct 843 VKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFS---------------LGLNP 887
Query 1116 -QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
G + + +L++ G ++ +P P +Y +M+ CW E + RPTF+ + +L+
Sbjct 888 YPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTRRPTFQQICSLLQ 943
Score = 52.4 bits (124), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 43/165 (26%), Positives = 75/165 (45%), Gaps = 22/165 (13%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV- 773
+ Q+A +++L +KN +H +V RN+LL +A K+ D G+ ++ +
Sbjct 791 SSQVAQGMAFLASKNCIHRDVAARNVLLTSGRVA-------KIGDFGLARDIMNDSNYIV 843
Query 774 ---ERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
R+P W+APE + ++ + D W +G L EI G P + K FY+
Sbjct 844 KGNARLPVKWMAPESIFDCVYTVQS--DVWSYGILLWEIFSLGLNPYPGILVNSK--FYK 899
Query 829 -----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
Q P + + ++ C EPT+RP+F+ I L +
Sbjct 900 LVKDGYQMAQPAFAPKNIYSIMQACWALEPTRRPTFQQICSLLQK 944
>sp|Q5MD89|VGFR3_DANRE Vascular endothelial growth factor receptor
3 OS=Danio rerio OX=7955 GN=flt4 PE=2 SV=1
Length=1357
Score = 117 bits (292), Expect = 5e-25, Method: Compositional matrix adjust.
Identities = 91/323 (28%), Positives = 142/323 (44%), Gaps = 73/323 (23%)
Query 903 LGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEH 958
LG G FGKV S++ +D + VAVK LK E+ IL + H +
Sbjct 872 LGHGAFGKVIEASIFGHD--KKSSANTVAVKMLKEGATASEHKALMSELKILIHIGNHLN 929
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---------------------------- 990
++ G C + L +++EY G+L ++L
Sbjct 930 VVNLLGACT-KPNGPLMVIVEYCKYGNLSNFLRAKREFFLPYRDRSPKTQSQVRRMIEAG 988
Query 991 ----------------PRHSIG--------LAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
PR ++ + L+ ++ Q+ GM +L ++ IHRDLAA
Sbjct 989 QASQSEHQPSTSSTNPPRVTVDDLWKTPLTIEDLICYSFQVARGMEFLASRKCIHRDLAA 1048
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RN+LL + +VKI DFGLA+ + + +Y R + + P+ W APE + + + SDVWS
Sbjct 1049 RNILLSENNVVKICDFGLARDIYKDPDYVR-KGNARLPLKWMAPESIFDKVYTSQSDVWS 1107
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
FGV L+E+ + +S P + E + L+ G R+ PD E+Y
Sbjct 1108 FGVLLWEIFS-LGASPYPGIQIDE------------DFCKRLKDGTRMRAPDNASPEIYG 1154
Query 1147 LMKNCWETEASFRPTFENLIPIL 1169
+M CW+ E RPTF L+ IL
Sbjct 1155 IMLACWQGEPRERPTFPALVEIL 1177
Score = 52.0 bits (123), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 41/168 (24%), Positives = 73/168 (43%), Gaps = 22/168 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V +
Sbjct 1028 QVARGMEFLASRKCIHRDLAARNILLSENNV-------VKICDFGLARDIYKDPDYVRKG 1080
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + ++ D W FG L EI G +P E F +R
Sbjct 1081 NARLPLKWMAPESIFDKV--YTSQSDVWSFGVLLWEIFSLGASPYPGIQIDED--FCKRL 1136
Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
+ R P+ + P++ + C EP +RP+F ++ L L N
Sbjct 1137 KDGTRMRAPDNASPEIYGIMLACWQGEPRERPTFPALVEILGDLLQEN 1184
>sp|A9SY39|M3K1A_PHYPA Mitogen-activated protein kinase kinase
kinase 1a OS=Physcomitrium patens OX=3218 GN=MEKK1a PE=2 SV=2
Length=759
Score = 115 bits (289), Expect = 5e-25, Method: Compositional matrix adjust.
Identities = 84/269 (31%), Positives = 132/269 (49%), Gaps = 31/269 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQ---EIDILRTLYHEH 958
LG G FG S+Y N G AVK + AD G R KQ EI +L + H +
Sbjct 432 LGSGTFG--SVYEGVARN---GTFFAVKEVNLADEGKLGRQAVKQLEREIALLSDIQHPN 486
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I++Y G ++ E L + +E + GSL + ++ + Q+ + +QI G+ YLH +
Sbjct 487 IVQYLGT--ERTEDKLYIFLELLNKGSLANLYRKYGLFYEQIKAYTEQILTGLKYLHDRK 544
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK-EYK 1077
IHRD+ N+L+D + +VK+ DFG+AK V E + + W APE + + +
Sbjct 545 IIHRDIKCANILVDTNGVVKLADFGMAKQV----EKFGFAKSFVGSAHWMAPEVVDPKQQ 600
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ +A+D+WS G T+ E+ T + PP LE I + + RGE P
Sbjct 601 YNFAADIWSLGCTVLEMAT-----EGPPFGELEFIAVFWK----------IGRGEAPLIP 645
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
D E+ + C + +AS RPT + L+
Sbjct 646 DDLEDELKDFIAQCLQVDASKRPTCDMLL 674
Score = 41.6 bits (96), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 68/299 (23%), Positives = 118/299 (39%), Gaps = 86/299 (29%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LG GT +VYEG R +E + DE L GR ++L +IAL
Sbjct 432 LGSGTFGSVYEGVARNGTFFAVKEVNLADEGKL--GRQAVKQL----------EREIAL- 478
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
+S + H ++ G + + E + G L L R+ G + ++ +
Sbjct 479 -------LSDIQHPNIVQYLGTERTEDKLYIFLELLNKGSL-ANLYRKYG---LFYEQIK 527
Query 715 A--QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
A +Q+ + L YL ++ ++H ++ NIL+ G+ +KL+D G+ ++
Sbjct 528 AYTEQILTGLKYLHDRKIIHRDIKCANILVDTNGV-------VKLADFGMA-------KQ 573
Query 773 VERIP----------WLAPECLPGGANSLSTAMDKWGFGATLLEICFD------------ 810
VE+ W+APE + + A D W G T+LE+ +
Sbjct 574 VEKFGFAKSFVGSAHWMAPEVV-DPKQQYNFAADIWSLGCTVLEMATEGPPFGELEFIAV 632
Query 811 ------GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
GEAPL +P+ +L +QCL + ++RP+ +L
Sbjct 633 FWKIGRGEAPL-----------------IPDDLEDELKDFIAQCLQVDASKRPTCDMLL 674
>sp|P13369|CSF1R_FELCA Macrophage colony-stimulating factor 1
receptor OS=Felis catus OX=9685 GN=CSF1R PE=2 SV=1
Length=980
Score = 115 bits (289), Expect = 8e-25, Method: Compositional matrix adjust.
Identities = 61/176 (35%), Positives = 101/176 (57%), Gaps = 18/176 (10%)
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
L LL F+ Q+ +GMA+L +++ IHRD+AARNVLL + R+ KIGDFGLA+ + Y
Sbjct 750 LRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGRVAKIGDFGLARDIMNDSNYI- 808
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA- 1115
V+ + PV W APE + + + SDVWS+G+ L+E+ + +G+
Sbjct 809 VKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFS---------------LGLNP 853
Query 1116 -QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
G + + +L++ G ++ +P P +Y +M+ CW E + RPTF+ + +L+
Sbjct 854 YPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTRRPTFQQICSLLQ 909
Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 40/159 (25%), Positives = 72/159 (45%), Gaps = 22/159 (14%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ Q+A +++L +KN +H +V RN+LL +A K+ D G+ ++ +
Sbjct 757 SSQVAQGMAFLASKNCIHRDVAARNVLLTSGRVA-------KIGDFGLARDIMNDSNYIV 809
Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
+ + W+APE + ++ + D W +G L EI G P + K FY+
Sbjct 810 KGNARLPVKWMAPESIFDCVYTVQS--DVWSYGILLWEIFSLGLNPYPGILVNSK--FYK 865
Query 829 -----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
Q P + + ++ C EPT+RP+F+ I
Sbjct 866 LVKDGYQMAQPAFAPKNIYSIMQACWALEPTRRPTFQQI 904
>sp|P07333|CSF1R_HUMAN Macrophage colony-stimulating factor 1
receptor OS=Homo sapiens OX=9606 GN=CSF1R PE=1 SV=2
Length=972
Score = 115 bits (289), Expect = 8e-25, Method: Compositional matrix adjust.
Identities = 61/176 (35%), Positives = 99/176 (56%), Gaps = 18/176 (10%)
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
L LL F+ Q+ +GMA+L +++ IHRD+AARNVLL N + KIGDFGLA+ + Y
Sbjct 752 LRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYI- 810
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA- 1115
V+ + PV W APE + + + SDVWS+G+ L+E+ + +G+
Sbjct 811 VKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFS---------------LGLNP 855
Query 1116 -QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
G + + +L++ G ++ +P P +Y +M+ CW E + RPTF+ + L+
Sbjct 856 YPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQICSFLQ 911
Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 42/159 (26%), Positives = 72/159 (45%), Gaps = 22/159 (14%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV- 773
+ Q+A +++L +KN +H +V RN+LL +A K+ D G+ ++ +
Sbjct 759 SSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVA-------KIGDFGLARDIMNDSNYIV 811
Query 774 ---ERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
R+P W+APE + ++ + D W +G L EI G P + K FY+
Sbjct 812 KGNARLPVKWMAPESIFDCVYTVQS--DVWSYGILLWEIFSLGLNPYPGILVNSK--FYK 867
Query 829 -----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
Q P + + ++ C EPT RP+F+ I
Sbjct 868 LVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQI 906
>sp|P42159|RTK2_GEOCY Class II receptor tyrosine kinase OS=Geodia
cydonium OX=6047 GN=TK PE=2 SV=2
Length=605
Score = 114 bits (285), Expect = 9e-25, Method: Compositional matrix adjust.
Identities = 74/226 (33%), Positives = 113/226 (50%), Gaps = 30/226 (13%)
Query 897 LKKIRDLGEGHFGKVSLY----------CY----DPTNDGTGEMVAVKALKADCGPQHRS 942
+++++ +G G FG V L C DP+ +VAVK LK D + R
Sbjct 346 IREVKQIGVGQFGAVVLAEMTGLSGSERCVPTKRDPSMLNGVALVAVKKLKPDVSEEVRQ 405
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-------- 994
+ +EI + L H+ I++ C K +VMEY+ G L +L ++
Sbjct 406 SFDKEIKFVSQLQHDSIVQLLAVCTH--SKHPFIVMEYMENGDLNQFLQKYQMVDDDSAL 463
Query 995 ----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
I + LL A QI GM YL + +Y+HRDLA RN L+ ++ +KI DFG+++ + E
Sbjct 464 YSNQIPPSTLLYMAVQIASGMVYLSSLNYVHRDLATRNCLVGSNFRIKISDFGMSRNLYE 523
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
YYRVR P+ W A E +F SD W++GVT++E+ T
Sbjct 524 -RVYYRVRGRAMLPIRWMATESFYG-RFSEKSDAWAYGVTVWEIYT 567
Score = 64.7 bits (156), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 50/186 (27%), Positives = 84/186 (45%), Gaps = 27/186 (15%)
Query 639 VVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V +K L P ++ +F + +SQ+ H + + VC +V EY+E+G L+
Sbjct 390 VAVKKLKPDVSEEVRQSFDKEIKFVSQLQHDSIVQLLAVCTHSKHPFIVMEYMENGDLNQ 449
Query 698 WLRRER----------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
+L++ + +P + + +A Q+AS + YL + N VH ++ RN L+
Sbjct 450 FLQKYQMVDDDSALYSNQIPPSTLLYMAVQIASGMVYLSSLNYVHRDLATRNCLV----- 504
Query 748 AEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFG 801
G++ IK+SD G+ R R I W+A E G S D W +G
Sbjct 505 --GSNFRIKISDFGMSRNLYERVYYRVRGRAMLPIRWMATESFYG---RFSEKSDAWAYG 559
Query 802 ATLLEI 807
T+ EI
Sbjct 560 VTVWEI 565
>sp|Q9FGB1|CBC2_ARATH Serine/threonine-protein kinase 52 OS=Arabidopsis
thaliana OX=3702 GN=CBC2 PE=1 SV=1
Length=385
Score = 111 bits (278), Expect = 9e-25, Method: Compositional matrix adjust.
Identities = 89/305 (29%), Positives = 137/305 (45%), Gaps = 56/305 (18%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ-HRS---------GWKQEIDILR 952
L G FG V YD G+ VAVK L D G + HRS + QE+ +
Sbjct 88 LARGTFGTVHRGIYD------GQDVAVKLL--DWGEEGHRSEAEIVSLRADFAQEVAVWH 139
Query 953 TLYHEHIIKYKGCCEDQGEKSLQL----------------VMEYVPLGSLRDYL---PRH 993
L H ++ K+ G G LQL V+EY+P G+L+ YL R
Sbjct 140 KLDHPNVTKFIGAT--MGASGLQLQTESGPLAMPNNICCVVVEYLPGGALKSYLIKNRRR 197
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ ++ A + G++YLH+Q +HRD+ N+LLD R VKI DFG+A+ V +
Sbjct 198 KLTFKIVVQLALDLARGLSYLHSQKIVHRDVKTENMLLDKTRTVKIADFGVAR-VEASNP 256
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
E G + + APE L + DV+SFG+ L+E+ +C P F E+
Sbjct 257 NDMTGETG--TLGYMAPEVLNGNPYNRKCDVYSFGICLWEI--YCCDMPYPDLTFSEVT- 311
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ ++ + R P CP + +MK CW+ RP + ++P+L+++
Sbjct 312 -----------SAVVRQNLRPDIPRCCPSALAAVMKRCWDANPDKRPEMDEVVPMLESID 360
Query 1174 EKYQG 1178
G
Sbjct 361 TTKGG 365
Score = 66.2 bits (160), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 87/329 (26%), Positives = 139/329 (42%), Gaps = 40/329 (12%)
Query 557 ETSNLIIMRGARASPRTLNLSQLSFHR-------VDQKEITQLSHLGQGTRTNVYEG--- 606
+T+ + I A +SP TLN R +D ++ + L +GT V+ G
Sbjct 43 DTTAVAIGGSASSSPVTLNGGGFVGKRKQRLEWEIDPSKLIIKTVLARGTFGTVHRGIYD 102
Query 607 --RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664
+ V+ EEG + + + D QE+ V K+ P+ A + L Q
Sbjct 103 GQDVAVKLLDWGEEGHRSEAEIVSLRADFAQEVAVWHKLDHPNVTKFIGATMGASGLQLQ 162
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV--AQQLASAL 722
LA + +C +V EY+ G L +L + R + +K+VV A LA L
Sbjct 163 TESGPLAMPNNICC------VVVEYLPGGALKSYLIKNRRR-KLTFKIVVQLALDLARGL 215
Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE----RIPW 778
SYL ++ +VH +V N+LL + + +K++D GV S + + +
Sbjct 216 SYLHSQKIVHRDVKTENMLLDK-------TRTVKIADFGVARVEASNPNDMTGETGTLGY 268
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEI-CFDGEAPLQSRSPSEKEHFYQRQHRLPE-P 836
+APE L G N + D + FG L EI C D P + SE RQ+ P+ P
Sbjct 269 MAPEVLNG--NPYNRKCDVYSFGICLWEIYCCD--MPYPDLTFSEVTSAVVRQNLRPDIP 324
Query 837 SC--PQLATLTSQCLTYEPTQRPSFRTIL 863
C LA + +C P +RP ++
Sbjct 325 RCCPSALAAVMKRCWDANPDKRPEMDEVV 353
>sp|Q55GU0|Y9955_DICDI Probable serine/threonine-protein kinase
DDB_G0267514 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0267514
PE=3 SV=1
Length=916
Score = 115 bits (288), Expect = 9e-25, Method: Compositional matrix adjust.
Identities = 90/280 (32%), Positives = 133/280 (48%), Gaps = 30/280 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--DCGPQHRSGWKQEIDILRTL 954
LK LGEG FG V + G VA+K +K D Q +++E+ IL L
Sbjct 662 LKISSKLGEGTFGVVYKGLW------RGSSVAIKQIKINEDVNNQVLEEFRKELTILSRL 715
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--FAQQICEGMA 1012
H +I+ C +L + EY+P GSL D L I + L A QI +GM
Sbjct 716 RHPNIVLLMAACT--APPNLCFITEYLPGGSLYDALHSKKIKMNMQLYKKLAIQIAQGMN 773
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
YLH IHRD+ + N+LLD VKI DFGL+K + E + + SP+ W +PE
Sbjct 774 YLHLSGVIHRDIKSLNLLLDEHMNVKICDFGLSKLKSKSTE---MTKSIGSPI-WMSPEL 829
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
L + DV++FG+ L+EL T L G+ Q+ + T+ L
Sbjct 830 LMGEDYTEKVDVYAFGIILWEL----------GTGELPYSGLDSVQLALAVTTKSL---- 875
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
R P P+ P ++ HL++ CW + RP+F ++ +L +
Sbjct 876 RPPIPNAWPYQLSHLIQACWHQDPLKRPSFTEILNLLNEI 915
Score = 62.8 bits (151), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 71/323 (22%), Positives = 127/323 (39%), Gaps = 41/323 (13%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
Q N++ G+ P + S + E+ S LG+GT VY+G R
Sbjct 627 QYNNQGNILKNSGSVVEPPSQQQQYFSDIEISFSELKISSKLGEGTFGVVYKGLWR---- 682
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVV-LKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672
G + + +K+ + ++ + F + +++S++ H ++
Sbjct 683 --------------------GSSVAIKQIKINEDVNNQVLEEFRKELTILSRLRHPNIVL 722
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVH 732
+ C P +TEY+ G L L ++ + M +A Q+A ++YL ++H
Sbjct 723 LMAACTAPPNLCFITEYLPGGSLYDALHSKKIKMNMQLYKKLAIQIAQGMNYLHLSGVIH 782
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---WLAPECLPGGAN 789
++ N+LL +K+ D G+ E + I W++PE L G
Sbjct 783 RDIKSLNLLLDE-------HMNVKICDFGLSKLKSKSTEMTKSIGSPIWMSPELLMG--E 833
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPSC--PQLATLTS 846
+ +D + FG L E+ GE P + + R P P+ QL+ L
Sbjct 834 DYTEKVDVYAFGIILWELG-TGELPYSGLDSVQLALAVTTKSLRPPIPNAWPYQLSHLIQ 892
Query 847 QCLTYEPTQRPSFRTILRDLTRL 869
C +P +RPSF IL L +
Sbjct 893 ACWHQDPLKRPSFTEILNLLNEI 915
>sp|Q5PP29|PBL4_ARATH Probable serine/threonine-protein kinase
PBL4 OS=Arabidopsis thaliana OX=3702 GN=PBL4 PE=2 SV=1
Length=412
Score = 112 bits (279), Expect = 9e-25, Method: Compositional matrix adjust.
Identities = 90/281 (32%), Positives = 131/281 (47%), Gaps = 19/281 (7%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+GEG FG V D P+ G+G +VAVK LK + HR W E+D L L+H
Sbjct 89 IGEGGFGYVYKGWIDERTLSPSKPGSGMVVAVKKLKEEGFQGHRQ-WLAEVDCLGRLHHM 147
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYL 1014
+++K G C +G+ LV EY+P GSL ++L R I + A G+A+L
Sbjct 148 NLVKLIGYCS-KGDHIRLLVYEYMPKGSLENHLFRRGAEPIPWRTRIKVAIGAARGLAFL 206
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H I+RD A N+LLD++ K+ DFGLAK P G + V + APE +
Sbjct 207 HEAQVIYRDFKASNILLDSEFNAKLSDFGLAKVGPTGDRTH-VSTQVMGTQGYAAPEYVA 265
Query 1075 EYKFYYASDVWSFGVTLYELLT---HCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLE 1129
+ SDV+SFGV L ELL+ D ++ + L I + V R+ +
Sbjct 266 TGRITAKSDVYSFGVVLLELLSGRLTVDKTKVGVERNLVDWAIPYLGDKRKVFRIMDTKL 325
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
G+ P K C + C E RP +++ L+
Sbjct 326 GGQ---YPHKGACLTANTALQCLNQEPKLRPKMSDVLSTLE 363
>sp|Q9ZQ31|STY13_ARATH Serine/threonine-protein kinase STY13 OS=Arabidopsis
thaliana OX=3702 GN=STY13 PE=1 SV=2
Length=411
Score = 111 bits (277), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 82/291 (28%), Positives = 138/291 (47%), Gaps = 44/291 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQH----RSGWKQEIDILRTLYHE 957
+G FGK+ Y+ GE VA+K L + + P+ ++QE+ +L L H
Sbjct 136 FAQGAFGKLYKGTYN------GEDVAIKILERPENSPEKAQFMEQQFQQEVSMLANLKHP 189
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ---ICEGMAYL 1014
+I+++ G C + +V EY GS+R +L R L L +Q + GMAY+
Sbjct 190 NIVRFIGAC--RKPMVWCIVTEYAKGGSVRQFLTRRQNRAVPLKLAVKQALDVARGMAYV 247
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP----VFWYAP 1070
H +++IHRDL + N+L+ D+ +KI DFG+A+ V+ +G +P W AP
Sbjct 248 HGRNFIHRDLKSDNLLISADKSIKIADFGVAR--------IEVQTEGMTPETGTYRWMAP 299
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT-ELLE 1129
E ++ + DV+SFG+ L+EL+T Q+ MT ++ ++
Sbjct 300 EMIQHRAYNQKVDVYSFGIVLWELITGLLPFQN---------------MTAVQAAFAVVN 344
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180
RG R P+ C + +M CW+ RP F ++ +L+ + A
Sbjct 345 RGVRPTVPNDCLPVLSDIMTRCWDANPEVRPCFVEVVKLLEAAETEIMTTA 395
Score = 59.3 bits (142), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 51/214 (24%), Positives = 96/214 (45%), Gaps = 17/214 (8%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL-RRERGHVPMAWKMVVAQQL 718
S+++ + H ++ G C + +VTEY + G + +L RR+ VP+ + A +
Sbjct 181 SMLANLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTRRQNRAVPLKLAVKQALDV 240
Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP- 777
A ++Y+ +N +H ++ N+L++ IK++D GV + E
Sbjct 241 ARGMAYVHGRNFIHRDLKSDNLLIS-------ADKSIKIADFGVARIEVQTEGMTPETGT 293
Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHR-- 832
W+APE + A + +D + FG L E+ G P Q+ + + R R
Sbjct 294 YRWMAPEMIQHRA--YNQKVDVYSFGIVLWEL-ITGLLPFQNMTAVQAAFAVVNRGVRPT 350
Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
+P P L+ + ++C P RP F +++ L
Sbjct 351 VPNDCLPVLSDIMTRCWDANPEVRPCFVEVVKLL 384
>sp|Q9ESL4|M3K20_MOUSE Mitogen-activated protein kinase kinase
kinase 20 OS=Mus musculus OX=10090 GN=Map3k20 PE=1 SV=1
Length=802
Score = 114 bits (286), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 87/282 (31%), Positives = 136/282 (48%), Gaps = 40/282 (14%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ + G G FG V Y + VAVK L ++E +IL L H
Sbjct 16 LQFFENCGGGSFGSV----YRAKWISQDKEVAVKKLLK---------IEKEAEILSVLSH 62
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAY 1013
+II++ G + + +V EY LGSL DY+ + + + ++ +A + +GM Y
Sbjct 63 RNIIQFYGVILE--PPNYGIVTEYASLGSLYDYINSNRSEEMDMEHIMTWATDVAKGMHY 120
Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
LH + IHRDL +RNV++ D ++KI DFG ++ V G P W AP
Sbjct 121 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLV---GTFP--WMAP 175
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E ++ D +S+GV L+E+LT + P K LE + +A ++E+
Sbjct 176 EVIQSLPVSETCDTYSYGVVLWEMLT-----REVPFKGLEGLQVAWL---------VVEK 221
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
ERL P CP L+ CWE +A RP+F+ +I IL+++
Sbjct 222 NERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESM 263
Score = 62.8 bits (151), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 61/234 (26%), Positives = 104/234 (44%), Gaps = 20/234 (9%)
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWK 711
L + A ++S +SH ++ +GV + P +VTEY G L ++ R + M
Sbjct 48 LKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMEHI 107
Query 712 MVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--GA 766
M A +A + YL + ++H ++ RN+++A G+ +K+ D G
Sbjct 108 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV-------LKICDFGASRFHNH 160
Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ V PW+APE + + +S D + +G L E+ E P + +
Sbjct 161 TTHMSLVGTFPWMAPEVIQ--SLPVSETCDTYSYGVVLWEM-LTREVPFKGLEGLQVAWL 217
Query 827 -YQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL-QPHNLAD 876
++ RL P SCP+ A L QC + +RPSF+ I+ L + NL D
Sbjct 218 VVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTNLPD 271
>sp|Q9SFB6|M3KE2_ARATH MAP3K epsilon protein kinase 2 OS=Arabidopsis
thaliana OX=3702 GN=MAP3KE2 PE=2 SV=1
Length=1367
Score = 115 bits (287), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 78/269 (29%), Positives = 136/269 (51%), Gaps = 28/269 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHII 960
++G+G +G+V Y + G+ VA+K + + G + + QEID+L+ L H++I+
Sbjct 25 EIGKGAYGRV----YIGLDLENGDFVAIKQVSLENIGQEDLNTIMQEIDLLKNLNHKNIV 80
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAYLHAQ 1017
KY G + + L +++EYV GSL + + + G + + ++ Q+ EG+ YLH Q
Sbjct 81 KYLGSLKTKTH--LHIILEYVENGSLANIIKPNKFGPFPESLVTVYIAQVLEGLVYLHEQ 138
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ N+L + LVK+ DFG+A + E + +P +W APE ++
Sbjct 139 GVIHRDIKGANILTTKEGLVKLADFGVATKLNEAD--FNTHSVVGTP-YWMAPEVIELSG 195
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
ASD+WS G T+ ELLT PP L Q + R+ + + P P
Sbjct 196 VCAASDIWSVGCTIIELLTCV-----PPYYDL------QPMPALYRIVQ----DDTPPIP 240
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
D ++ ++ C++ ++ RP + L+
Sbjct 241 DSLSPDITDFLRLCFKKDSRQRPDAKTLL 269
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 50/210 (24%), Positives = 87/210 (41%), Gaps = 17/210 (8%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLA 719
L+ ++H ++ G ++ EYVE+G L ++ + G P + V Q+
Sbjct 70 LLKNLNHKNIVKYLGSLKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVTVYIAQVL 129
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777
L YL + ++H ++ G NIL + GL +KL+D GV + +
Sbjct 130 EGLVYLHEQGVIHRDIKGANILTTKEGL-------VKLADFGVATKLNEADFNTHSVVGT 182
Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEI--CFDGEAPLQSRSPSEKEHFYQRQHRL 833
W+APE + + + A D W G T++E+ C LQ P+ +
Sbjct 183 PYWMAPEVIE--LSGVCAASDIWSVGCTIIELLTCVPPYYDLQPM-PALYRIVQDDTPPI 239
Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
P+ P + C + QRP +T+L
Sbjct 240 PDSLSPDITDFLRLCFKKDSRQRPDAKTLL 269
>sp|Q9NYL2|M3K20_HUMAN Mitogen-activated protein kinase kinase
kinase 20 OS=Homo sapiens OX=9606 GN=MAP3K20 PE=1 SV=3
Length=800
Score = 114 bits (285), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 87/282 (31%), Positives = 136/282 (48%), Gaps = 40/282 (14%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ + G G FG V Y + VAVK L ++E +IL L H
Sbjct 16 LQFFENCGGGSFGSV----YRAKWISQDKEVAVKKLLK---------IEKEAEILSVLSH 62
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAY 1013
+II++ G + + +V EY LGSL DY+ + + + ++ +A + +GM Y
Sbjct 63 RNIIQFYGVILE--PPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY 120
Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
LH + IHRDL +RNV++ D ++KI DFG ++ V G P W AP
Sbjct 121 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLV---GTFP--WMAP 175
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E ++ D +S+GV L+E+LT + P K LE + +A ++E+
Sbjct 176 EVIQSLPVSETCDTYSYGVVLWEMLT-----REVPFKGLEGLQVAW---------LVVEK 221
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
ERL P CP L+ CWE +A RP+F+ +I IL+++
Sbjct 222 NERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESM 263
Score = 62.4 bits (150), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 58/226 (26%), Positives = 101/226 (45%), Gaps = 19/226 (8%)
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWK 711
L + A ++S +SH ++ +GV + P +VTEY G L ++ R + M
Sbjct 48 LKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHI 107
Query 712 MVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--GA 766
M A +A + YL + ++H ++ RN+++A G+ +K+ D G
Sbjct 108 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV-------LKICDFGASRFHNH 160
Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ V PW+APE + + +S D + +G L E+ E P + +
Sbjct 161 TTHMSLVGTFPWMAPEVIQ--SLPVSETCDTYSYGVVLWEM-LTREVPFKGLEGLQVAWL 217
Query 827 -YQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
++ RL P SCP+ A L QC + +RPSF+ I+ L +
Sbjct 218 VVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESM 263
>sp|F1QVU0|LTK_DANRE Tyrosine-protein kinase receptor OS=Danio
rerio OX=7955 GN=ltk PE=1 SV=1
Length=1530
Score = 115 bits (287), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 92/310 (30%), Positives = 137/310 (44%), Gaps = 44/310 (14%)
Query 894 KRYLKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
++ + +R LG G FG+V + T VA+K L C Q + E I+
Sbjct 932 RKNITLLRALGHGAFGEVYEGQVLGMNGENTAMQVAIKTLPEICSEQDEMDFLMEALIMS 991
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL-----GSLRDYL----PRHS----IGLAQ 999
H++I++ G SLQ++ ++ L G ++ +L PR + + + +
Sbjct 992 KFSHQNIVRCIGV-------SLQILPRFILLELMTGGDMKSFLRLNRPRTNHSSSLSMLE 1044
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN---DRLVKIGDFGLAKAVPEGHEYYR 1056
LL A+ I G YL H+IHRD+AARN LL DR+ KIGDFG+A+ + YYR
Sbjct 1045 LLHMARDIALGCRYLEENHFIHRDIAARNCLLTCPGPDRVAKIGDFGMARDIYRA-SYYR 1103
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
PV W PE E F +D WSFGV L+E+ + L +
Sbjct 1104 KGGRAMLPVKWMPPEAFLEGIFTCKTDTWSFGVLLWEIFS--------------LGYMPY 1149
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
T + E + G R+ P CP VY +M CW+ RP F ++ + Y
Sbjct 1150 PCKTNQEVLEFVTGGGRMDPPKSCPGPVYRIMTQCWQHCPEHRPNFTTILERI-----NY 1204
Query 1177 QGQAPSVFSV 1186
Q P V +
Sbjct 1205 CTQDPDVINT 1214
Score = 70.1 bits (170), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 79/311 (25%), Positives = 128/311 (41%), Gaps = 42/311 (14%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
+ +LS+L V +K IT L LG G VYEG++ M+ E+
Sbjct 920 KAASLSELK--EVPRKNITLLRALGHGAFGEVYEGQVL----------GMNGEN------ 961
Query 632 DRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
++V +K L + + F A +MS+ SH ++ GV ++ ++ E +
Sbjct 962 ---TAMQVAIKTLPEICSEQDEMDFLMEALIMSKFSHQNIVRCIGVSLQILPRFILLELM 1018
Query 691 EHGPLDVWLRRERGHVPMAWKMV------VAQQLASALSYLENKNLVHGNVCGRNILLAR 744
G + +LR R + + +A+ +A YLE + +H ++ RN LL
Sbjct 1019 TGGDMKSFLRLNRPRTNHSSSLSMLELLHMARDIALGCRYLEENHFIHRDIAARNCLLT- 1077
Query 745 LGLAEGTSPFIKLSDPGVG----LGALSREERVERIP--WLAPECLPGGANSLSTAMDKW 798
G K+ D G+ + R+ +P W+ PE G + T D W
Sbjct 1078 ---CPGPDRVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPPEAFLEGIFTCKT--DTW 1132
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQR 856
FG L EI G P ++ E F R+ P SCP + + +QC + P R
Sbjct 1133 SFGVLLWEIFSLGYMPYPCKTNQEVLEFVTGGGRMDPPKSCPGPVYRIMTQCWQHCPEHR 1192
Query 857 PSFRTILRDLT 867
P+F TIL +
Sbjct 1193 PNFTTILERIN 1203
>sp|Q91909|KIT_XENLA Mast/stem cell growth factor receptor-related
protein Kit OS=Xenopus laevis OX=8355 GN=kit PE=2 SV=1
Length=954
Score = 114 bits (285), Expect = 2e-24, Method: Compositional matrix adjust.
Identities = 105/419 (25%), Positives = 177/419 (42%), Gaps = 99/419 (24%)
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS-PASDPTVFHKRYLKK 899
L + L Y+ Q+P + + + + +N + ++P P + F + L
Sbjct 523 LMCIAVAVLMYKYLQKPKYEIQWKVVEEINGNNY---VYIDPTQLPYDNKWEFPRDRLCF 579
Query 900 IRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHE 957
+ LG G FGKV Y + + VAVK LK R E+ +L L +H+
Sbjct 580 GKILGAGAFGKVVEATAYGLLKEDSRLTVAVKMLKPSAHSTEREALMSELKVLSYLGHHK 639
Query 958 HIIKYKG--------------CC--------------------EDQGEKSL--------- 974
+I+ G CC ED E +L
Sbjct 640 NIVNLLGACTVGGPTLVITEYCCYGDLLNYLRRKRDSFICPKFEDNSEAALYKNLLNTRD 699
Query 975 ---QLVMEYVPL-----------------GSLRDY-----LPRH---SIGLAQLLLFAQQ 1006
+ + EY+ + GS D +P ++ L+ F+ Q
Sbjct 700 MGCEGMSEYIDMKPAVSYVVPTKTDKRRSGSFGDQDVSVSIPEEDDLALDTEDLINFSYQ 759
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+ +GM +L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ + PV
Sbjct 760 VAQGMNFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIRNDSNYV-VKGNARLPVK 818
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP----PTKFLELIGIAQGQMTVL 1122
W APE + + + SDVWS+G+ L+E+ + SS P +KF ++I
Sbjct 819 WMAPESIFHCVYTFESDVWSYGILLWEIFS-LGSSPYPRIPVDSKFYKMI---------- 867
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
+ G R+ P+ P E+Y +M++CW ++ RPTF+ ++ +++ +G P
Sbjct 868 ------KDGYRMMSPECAPLEMYEIMRSCWNSDPLKRPTFKQIVQMVEQQLSDSKGNTP 920
Score = 53.1 bits (126), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 38/160 (24%), Positives = 73/160 (46%), Gaps = 20/160 (13%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+ Q+A +++L +KN +H ++ RNILL K+ D G+ + V
Sbjct 757 SYQVAQGMNFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIRNDSNYVV 809
Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF-- 826
+ + W+APE + + + D W +G L EI G +P R P + + +
Sbjct 810 KGNARLPVKWMAPESIFHCVYTFES--DVWSYGILLWEIFSLGSSPY-PRIPVDSKFYKM 866
Query 827 YQRQHRLPEPSCP--QLATLTSQCLTYEPTQRPSFRTILR 864
+ +R+ P C ++ + C +P +RP+F+ I++
Sbjct 867 IKDGYRMMSPECAPLEMYEIMRSCWNSDPLKRPTFKQIVQ 906
Score = 37.7 bits (86), Expect = 0.83, Method: Compositional matrix adjust.
Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 12/74 (16%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVS-------HTHLAFVHGVCVRGPENIMVTEY 689
L V +K+L PS H E +LMS++ H ++ + G C G +++TEY
Sbjct 606 LTVAVKMLKPSAHST-----EREALMSELKVLSYLGHHKNIVNLLGACTVGGPTLVITEY 660
Query 690 VEHGPLDVWLRRER 703
+G L +LRR+R
Sbjct 661 CCYGDLLNYLRRKR 674
>sp|Q7T2V3|M3K10_XENLA Mitogen-activated protein kinase kinase
kinase 10 OS=Xenopus laevis OX=8355 GN=map3k10 PE=1 SV=1
Length=1005
Score = 114 bits (285), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 95/294 (32%), Positives = 138/294 (47%), Gaps = 43/294 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ---HRSGWKQEIDILRTLYHEHI 959
+G G FGKV + E VAVKA++ D +QE I L H +I
Sbjct 124 IGVGGFGKVYKGLW------RDEEVAVKAVRHDPDEDINVTAENVRQEAKIFCMLCHPNI 177
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I G C L LVMEY G L L + L+ +A QI +GM YLH +
Sbjct 178 IALTGVC--LKPPHLCLVMEYARGGPLHRALAGKKVPAHVLVNWAVQIAKGMTYLHNEAI 235
Query 1020 ---IHRDLAARNVLL----DNDRL----VKIGDFGLAKAVPEGHEYYRVREDGDSPVF-W 1067
IHRDL + N+L+ +ND L + I DFGLA+ E+ + + + + W
Sbjct 236 VPIIHRDLGSSNILILEKAENDDLFNKTLNITDFGLAR------EWQKTTKMSAAGTYAW 289
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE ++ F +SDVWSFGV L+ELLT P + ++ + +A G + + +LT
Sbjct 290 MAPEVIRLSLFSKSSDVWSFGVLLWELLTG-----EVPYREIDALAVAYG-VAMNKLT-- 341
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
LP P CP +++ CW+ + RPTF ++ L T+ + Q P
Sbjct 342 ------LPIPSTCPEPFVRILEACWDPDPHSRPTFSCILEQLTTIEQSAMFQMP 389
Score = 65.9 bits (159), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 69/253 (27%), Positives = 109/253 (43%), Gaps = 22/253 (9%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
RD ++ V D + A + A + + H ++ + GVC++ P +V EY
Sbjct 138 RDEEVAVKAVRHDPDEDINVTAENVRQEAKIFCMLCHPNIIALTGVCLKPPHLCLVMEYA 197
Query 691 EHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKNLV---HGNVCGRNILLARL 745
GPL L ++ HV + W A Q+A ++YL N+ +V H ++ NIL+ L
Sbjct 198 RGGPLHRALAGKKVPAHVLVNW----AVQIAKGMTYLHNEAIVPIIHRDLGSSNILI--L 251
Query 746 GLAEGTSPFIK-LSDPGVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800
AE F K L+ GL ++ W+APE + + S + D W F
Sbjct 252 EKAENDDLFNKTLNITDFGLAREWQKTTKMSAAGTYAWMAPEVI--RLSLFSKSSDVWSF 309
Query 801 GATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRP 857
G L E+ GE P + + + LP PS CP+ + C +P RP
Sbjct 310 GVLLWEL-LTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFVRILEACWDPDPHSRP 368
Query 858 SFRTILRDLTRLQ 870
+F IL LT ++
Sbjct 369 TFSCILEQLTTIE 381
>sp|Q00495|CSF1R_RAT Macrophage colony-stimulating factor 1 receptor
OS=Rattus norvegicus OX=10116 GN=Csf1r PE=1 SV=1
Length=978
Score = 114 bits (284), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 62/185 (34%), Positives = 104/185 (56%), Gaps = 18/185 (10%)
Query 988 DYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
D P + L LL F+ Q+ +GMA+L +++ IHRD+AARNVLL + + KIGDFGLA+
Sbjct 741 DKEPSRPLELWDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGHVAKIGDFGLARD 800
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ Y V+ + PV W APE + + SDVWS+G+ L+E+ +
Sbjct 801 IMNDSNYV-VKGNARLPVKWMAPESILYCVYTVQSDVWSYGILLWEIFS----------- 848
Query 1108 FLELIGIA--QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+G+ G + + +L++ G ++ +P P +Y +M++CW+ E + RPTF+ +
Sbjct 849 ----LGLNPYPGILVNNKFYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPTFQQI 904
Query 1166 IPILK 1170
+L+
Sbjct 905 CFLLQ 909
Score = 53.9 bits (128), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 52/209 (25%), Positives = 93/209 (44%), Gaps = 35/209 (17%)
Query 686 VTEYVEHGPL-----DVWLRRERGHVPM----AWKMV-VAQQLASALSYLENKNLVHGNV 735
V YVE P+ D + +++ P W ++ + Q+A +++L +KN +H +V
Sbjct 718 VDTYVEMRPVSTSSSDSFFKQDLDKEPSRPLELWDLLHFSSQVAQGMAFLASKNCIHRDV 777
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGAN 789
RN+LL +A K+ D G+ ++ V + + W+APE +
Sbjct 778 AARNVLLTSGHVA-------KIGDFGLARDIMNDSNYVVKGNARLPVKWMAPESILYCVY 830
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-----RQHRLPEPSCPQLATL 844
++ + D W +G L EI G P + K FY+ Q P + + ++
Sbjct 831 TVQS--DVWSYGILLWEIFSLGLNPYPGILVNNK--FYKLVKDGYQMAQPVFAPKNIYSI 886
Query 845 TSQCLTYEPTQRPSFRTI---LRDLTRLQ 870
C EPT+RP+F+ I L++ RL+
Sbjct 887 MQSCWDLEPTRRPTFQQICFLLQEQARLE 915
>sp|P27450|CST_ARATH Probable serine/threonine-protein kinase
CST OS=Arabidopsis thaliana OX=3702 GN=CST PE=1 SV=2
Length=419
Score = 110 bits (275), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 83/282 (29%), Positives = 142/282 (50%), Gaps = 15/282 (5%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LG+G FGKV D P+ G+G +VA+K L ++ Q + W+ E++ L L H
Sbjct 92 LGQGGFGKVYRGWVDATTLAPSRVGSGMIVAIKRLNSES-VQGFAEWRSEVNFLGMLSHR 150
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI--CEGMAYLH 1015
+++K G C + +K L LV E++P GSL +L R + L I G+A+LH
Sbjct 151 NLVKLLGYCRE--DKELLLVYEFMPKGSLESHLFRRNDPFPWDLRIKIVIGAARGLAFLH 208
Query 1016 A--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ + I+RD A N+LLD++ K+ DFGLAK P E V + APE +
Sbjct 209 SLQREVIYRDFKASNILLDSNYDAKLSDFGLAKLGP-ADEKSHVTTRIMGTYGYAAPEYM 267
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVL-RLTELLERG 1131
Y SDV++FGV L E++T + + P L+ + +++ R+ +++++G
Sbjct 268 ATGHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLVDWLRPELSNKHRVKQIMDKG 327
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ K E+ + +C E + RP + ++ +L+ +
Sbjct 328 IKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEVLEHIQ 369
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 72/309 (23%), Positives = 121/309 (39%), Gaps = 52/309 (17%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
S LGQG VY G + D L P R G + V +K L+
Sbjct 90 SMLGQGGFGKVYRGWV--------------DATTLAPSR-VGSGMIVAIKRLNSESVQGF 134
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
+ + + +SH +L + G C E ++V E++ G L+ L R P ++
Sbjct 135 AEWRSEVNFLGMLSHRNLVKLLGYCREDKELLLVYEFMPKGSLESHLFRRNDPFPWDLRI 194
Query 713 VVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSR 769
+ A L++L + + +++ + NILL ++ KLSD G+ LG
Sbjct 195 KIVIGAARGLAFLHSLQREVIYRDFKASNILL-------DSNYDAKLSDFGLAKLGPADE 247
Query 770 EERV-ERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ V RI + APE + G L D + FG LLEI G ++ P +E
Sbjct 248 KSHVTTRIMGTYGYAAPEYMATG--HLYVKSDVFAFGVVLLEI-MTGLTAHNTKRPRGQE 304
Query 825 HFY-------QRQHRLPE------------PSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+HR+ + ++A +T C+ +P RP + ++
Sbjct 305 SLVDWLRPELSNKHRVKQIMDKGIKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEV 364
Query 866 LTRLQPHNL 874
L +Q N+
Sbjct 365 LEHIQGLNV 373
>sp|Q9LJD8|M3KE1_ARATH MAP3K epsilon protein kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=M3KE1 PE=1 SV=1
Length=1368
Score = 114 bits (285), Expect = 3e-24, Method: Compositional matrix adjust.
Identities = 79/269 (29%), Positives = 137/269 (51%), Gaps = 28/269 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHII 960
++G+G +G+V Y + G+ VA+K + + Q + QEID+L+ L H++I+
Sbjct 25 EIGKGAYGRV----YKGLDLENGDFVAIKQVSLENIVQEDLNTIMQEIDLLKNLNHKNIV 80
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAYLHAQ 1017
KY G + + L +++EYV GSL + + + G + + ++ Q+ EG+ YLH Q
Sbjct 81 KYLGSSKTKTH--LHIILEYVENGSLANIIKPNKFGPFPESLVAVYIAQVLEGLVYLHEQ 138
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ N+L + LVK+ DFG+A + E +P +W APE ++
Sbjct 139 GVIHRDIKGANILTTKEGLVKLADFGVATKLNEAD--VNTHSVVGTP-YWMAPEVIEMSG 195
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
ASD+WS G T+ ELLT C PP + +L Q + R+ + + P P
Sbjct 196 VCAASDIWSVGCTVIELLT-C----VPP--YYDL----QPMPALFRIVQ----DDNPPIP 240
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
D ++ ++ C++ ++ RP + L+
Sbjct 241 DSLSPDITDFLRQCFKKDSRQRPDAKTLL 269
Score = 59.7 bits (143), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 51/210 (24%), Positives = 88/210 (42%), Gaps = 17/210 (8%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLA 719
L+ ++H ++ G ++ EYVE+G L ++ + G P + V Q+
Sbjct 70 LLKNLNHKNIVKYLGSSKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVAVYIAQVL 129
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777
L YL + ++H ++ G NIL + GL +KL+D GV + +
Sbjct 130 EGLVYLHEQGVIHRDIKGANILTTKEGL-------VKLADFGVATKLNEADVNTHSVVGT 182
Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEI--CFDGEAPLQSRSPSEKEHFYQRQHRL 833
W+APE + + + A D W G T++E+ C LQ P+ +
Sbjct 183 PYWMAPEVIE--MSGVCAASDIWSVGCTVIELLTCVPPYYDLQPM-PALFRIVQDDNPPI 239
Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
P+ P + QC + QRP +T+L
Sbjct 240 PDSLSPDITDFLRQCFKKDSRQRPDAKTLL 269
>sp|P09581|CSF1R_MOUSE Macrophage colony-stimulating factor 1
receptor OS=Mus musculus OX=10090 GN=Csf1r PE=1 SV=3
Length=977
Score = 113 bits (283), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 60/176 (34%), Positives = 102/176 (58%), Gaps = 18/176 (10%)
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
L LL F+ Q+ +GMA+L +++ IHRD+AARNVLL + + KIGDFGLA+ + Y
Sbjct 750 LWDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGHVAKIGDFGLARDIMNDSNYV- 808
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA- 1115
V+ + PV W APE + + + SDVWS+G+ L+E+ + +G+
Sbjct 809 VKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFS---------------LGLNP 853
Query 1116 -QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
G + + +L++ G ++ +P P +Y +M++CW+ E + RPTF+ + +L+
Sbjct 854 YPGILVNNKFYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPTFQQICFLLQ 909
Score = 53.9 bits (128), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 45/176 (26%), Positives = 81/176 (46%), Gaps = 26/176 (15%)
Query 710 WKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
W ++ + Q+A +++L +KN +H +V RN+LL +A K+ D G+ ++
Sbjct 751 WDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGHVA-------KIGDFGLARDIMN 803
Query 769 REERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
V + + W+APE + ++ + D W +G L EI G P +
Sbjct 804 DSNYVVKGNARLPVKWMAPESIFDCVYTVQS--DVWSYGILLWEIFSLGLNPYPGILVNN 861
Query 823 KEHFYQ-----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI---LRDLTRLQ 870
K FY+ Q P + + ++ C EPT+RP+F+ I L++ RL+
Sbjct 862 K--FYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPTFQQICFLLQEQARLE 915
>sp|P35968|VGFR2_HUMAN Vascular endothelial growth factor receptor
2 OS=Homo sapiens OX=9606 GN=KDR PE=1 SV=2
Length=1356
Score = 114 bits (284), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 73/197 (37%), Positives = 103/197 (52%), Gaps = 20/197 (10%)
Query 971 EKSLQLVMEY-VPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029
EKSL V E P +D+L L L+ ++ Q+ +GM +L ++ IHRDLAARN+
Sbjct 980 EKSLSDVEEEEAPEDLYKDFLT-----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNI 1034
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
LL +VKI DFGLA+ + + +Y R + D P+ W APE + + + SDVWSFGV
Sbjct 1035 LLSEKNVVKICDFGLARDIYKDPDYVR-KGDARLPLKWMAPETIFDRVYTIQSDVWSFGV 1093
Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149
L+E+ + +S P K E L+ G R+ PD E+Y M
Sbjct 1094 LLWEIFS-LGASPYPGVKIDE------------EFCRRLKEGTRMRAPDYTTPEMYQTML 1140
Query 1150 NCWETEASFRPTFENLI 1166
+CW E S RPTF L+
Sbjct 1141 DCWHGEPSQRPTFSELV 1157
Score = 57.4 bits (137), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 50/199 (25%), Positives = 87/199 (44%), Gaps = 38/199 (19%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V +
Sbjct 1011 QVAKGMEFLASRKCIHRDLAARNILLSEKNV-------VKICDFGLARDIYKDPDYVRKG 1063
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--EHFYQ 828
+ W+APE + ++ + D W FG L EI G +P P K E F +
Sbjct 1064 DARLPLKWMAPETIFDRVYTIQS--DVWSFGVLLWEIFSLGASPY----PGVKIDEEFCR 1117
Query 829 R-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN---------- 873
R + R P+ + P++ C EP+QRP+F ++ L L N
Sbjct 1118 RLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDGKDYIV 1177
Query 874 --LADVLTVNPDSPASDPT 890
+++ L++ DS S PT
Sbjct 1178 LPISETLSMEEDSGLSLPT 1196
>sp|Q8AXC6|KIT_TAKRU Mast/stem cell growth factor receptor Kit
OS=Takifugu rubripes OX=31033 GN=kit PE=3 SV=1
Length=984
Score = 113 bits (283), Expect = 5e-24, Method: Compositional matrix adjust.
Identities = 58/173 (34%), Positives = 96/173 (55%), Gaps = 14/173 (8%)
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
S+ LL F+ Q+ +GM +L +++ IHRDLAARN+LL R+ KI DFGLA+ +
Sbjct 752 SLDTEDLLSFSYQVAKGMEFLTSKNCIHRDLAARNILLTQGRVAKICDFGLARDINTDSN 811
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
Y V+ + PV W +PE + E + + SDVWS+G+ L+E+ + +S
Sbjct 812 YV-VKGNARLPVKWMSPESIFECVYTFESDVWSYGILLWEIFSLGNSPYP---------- 860
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
G + +L++ G R+ P+ P E+Y +M++CW+ + RP F ++
Sbjct 861 ---GMPVDAKFYKLIKEGYRMDAPEFAPSEMYQIMRSCWDADPLNRPPFRKVV 910
Score = 48.1 bits (113), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 39/161 (24%), Positives = 71/161 (44%), Gaps = 22/161 (14%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L +KN +H ++ RNILL + +A K+ D G+ + V +
Sbjct 764 QVAKGMEFLTSKNCIHRDLAARNILLTQGRVA-------KICDFGLARDINTDSNYVVKG 816
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--- 827
+ W++PE + + + D W +G L EI G +P K FY
Sbjct 817 NARLPVKWMSPESIFECVYTFES--DVWSYGILLWEIFSLGNSPYPGMPVDAK--FYKLI 872
Query 828 QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
+ +R+ PE + ++ + C +P RP FR ++ +
Sbjct 873 KEGYRMDAPEFAPSEMYQIMRSCWDADPLNRPPFRKVVERI 913
Score = 42.4 bits (98), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 38/147 (26%), Positives = 65/147 (44%), Gaps = 8/147 (5%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS-PASDPTVFHKRYLKKIRDLGEGH 907
L Y+ Q+P ++ + + + +N + ++P P F ++ L+ + LG G
Sbjct 533 LFYKYMQKPKYQIQWKVIEGIHGNNY---VYIDPTQLPYDHQWEFPRKNLRFGKTLGSGA 589
Query 908 FGK-VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGC 965
FGK V Y N+ + VAVK LK+ + E+ +L L H +I+ G
Sbjct 590 FGKVVEATAYGLANEDSMMTVAVKMLKSSAHSTEKEALMSELKVLIYLGNHINIVNLLGA 649
Query 966 CEDQGEKSLQLVMEYVPLGSLRDYLPR 992
C G ++ EY G L ++L R
Sbjct 650 CTVGGPT--LVITEYCCFGDLLNFLRR 674
>sp|Q21041|VER4_CAEEL Tyrosine-protein kinase receptor ver-4 OS=Caenorhabditis
elegans OX=6239 GN=ver-4 PE=3 SV=2
Length=1216
Score = 113 bits (283), Expect = 5e-24, Method: Compositional matrix adjust.
Identities = 72/212 (34%), Positives = 101/212 (48%), Gaps = 31/212 (15%)
Query 980 YVPLGSLRDYLPRHSIGLAQLLL-------------FAQQICEGMAYLHAQHYIHRDLAA 1026
Y+ L ++R+ +P+ + QLL+ QI GM +L +HRDLA
Sbjct 986 YIFLTNVRENVPKREVEKEQLLIDEFNSLCTSDLLSIGLQIANGMDWLANIPCVHRDLAC 1045
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS--PVFWYAPECLKEYKFYYASDV 1084
RNVL+ ++++I DFGLAK + YYRVRE D+ PV W E + + F SDV
Sbjct 1046 RNVLISKTKIIRIADFGLAKKHTD-KAYYRVRESLDTPLPVRWMPLESITDLTFTQKSDV 1104
Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144
WS+G+ LYE+ T L G L E ++ G RP C +V
Sbjct 1105 WSYGICLYEIFT--------------LGGTPYPDCPNFSLVEYIKTGNINKRPSNCHKDV 1150
Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
Y +MK CW+ RPTF I + K H +Y
Sbjct 1151 YKIMKMCWQASPDDRPTFAECIKLFKN-HIQY 1181
>sp|Q8JFR5|KITA_DANRE Mast/stem cell growth factor receptor kita
OS=Danio rerio OX=7955 GN=kita PE=2 SV=2
Length=976
Score = 113 bits (282), Expect = 6e-24, Method: Compositional matrix adjust.
Identities = 64/205 (31%), Positives = 107/205 (52%), Gaps = 16/205 (8%)
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYIH 1021
G + +SL Y ++ + L + L LL F+ Q+ +GM +L +++ IH
Sbjct 716 GILSSENRRSLNKGDSYSDSDAVSEILQEDGLTLDTEDLLSFSYQVAKGMDFLASKNCIH 775
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RDLAARN+LL R+ KI DFGLA+ + Y V+ + PV W +PE + E + +
Sbjct 776 RDLAARNILLTQGRVAKICDFGLARDITTDSNYV-VKGNARLPVKWMSPESIFECVYTFE 834
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
SDVWS+G+ L+E+ + SS P G + ++++ G R+ P+ P
Sbjct 835 SDVWSYGILLWEIFS-LGSSPYP------------GMPVDSKFYKMIKEGYRMESPEFSP 881
Query 1142 CEVYHLMKNCWETEASFRPTFENLI 1166
E+Y +M +CW+ + RP+F ++
Sbjct 882 SEMYDIMHSCWDADPVKRPSFSKIV 906
Score = 51.6 bits (122), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 41/161 (25%), Positives = 72/161 (45%), Gaps = 22/161 (14%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L +KN +H ++ RNILL + +A K+ D G+ + V +
Sbjct 760 QVAKGMDFLASKNCIHRDLAARNILLTQGRVA-------KICDFGLARDITTDSNYVVKG 812
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--- 827
+ W++PE + + + D W +G L EI G +P K FY
Sbjct 813 NARLPVKWMSPESIFECVYTFES--DVWSYGILLWEIFSLGSSPYPGMPVDSK--FYKMI 868
Query 828 QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
+ +R+ PE S ++ + C +P +RPSF I+ +
Sbjct 869 KEGYRMESPEFSPSEMYDIMHSCWDADPVKRPSFSKIVEKI 909
Score = 34.7 bits (78), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 12/74 (16%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689
+ V +K+L PS H E +LMS++ +H ++ + G C G +++TEY
Sbjct 609 MTVAVKMLKPSAHAT-----EKEALMSELKVLSYLGNHINIVNLLGACTVGGPTLVITEY 663
Query 690 VEHGPLDVWLRRER 703
G L +LRR R
Sbjct 664 CCFGDLLNFLRRRR 677
>sp|Q8UVR8|CSF12_TAKRU Macrophage colony-stimulating factor 1
receptor 2 OS=Takifugu rubripes OX=31033 GN=csf1r2 PE=3 SV=1
Length=1019
Score = 113 bits (282), Expect = 6e-24, Method: Compositional matrix adjust.
Identities = 61/178 (34%), Positives = 99/178 (56%), Gaps = 20/178 (11%)
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ LL F+ Q+ +G+ +L ++ IHRD+AARNVLL + R+ KI DFGLA+ + + +
Sbjct 799 LSFGDLLSFSHQVAQGLDFLSTRNCIHRDVAARNVLLTDHRVAKICDFGLARDI-QNDDS 857
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS---SQSPPTKFLEL 1111
Y V+ + PV W APE + + + SDVWS+GV L+E+ + S + + T F ++
Sbjct 858 YIVQGNARLPVKWMAPESIFQCVYTVQSDVWSYGVLLWEIFSLGKSPYPNVAVDTHFYKM 917
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
I + G + +PD P E+Y LM +CW E + RPTF+ + ++
Sbjct 918 I----------------KDGRHMTQPDFAPVEMYQLMTHCWSLEPTDRPTFKMICQLI 959
Score = 62.8 bits (151), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 46/170 (27%), Positives = 81/170 (48%), Gaps = 22/170 (13%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV- 773
+ Q+A L +L +N +H +V RN+LL +A K+ D G+ + + +
Sbjct 808 SHQVAQGLDFLSTRNCIHRDVAARNVLLTDHRVA-------KICDFGLARDIQNDDSYIV 860
Query 774 ---ERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
R+P W+APE + ++ + D W +G L EI G++P + + HFY+
Sbjct 861 QGNARLPVKWMAPESIFQCVYTVQS--DVWSYGVLLWEIFSLGKSPYPNVAV--DTHFYK 916
Query 829 -----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
R P+ + ++ L + C + EPT RP+F+ I + + RL N
Sbjct 917 MIKDGRHMTQPDFAPVEMYQLMTHCWSLEPTDRPTFKMICQLIDRLLQSN 966
>sp|Q5XJV6|LMTK3_MOUSE Serine/threonine-protein kinase LMTK3 OS=Mus
musculus OX=10090 GN=Lmtk3 PE=1 SV=1
Length=1424
Score = 113 bits (282), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 79/232 (34%), Positives = 116/232 (50%), Gaps = 23/232 (10%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
P S S P +++L ++++G G FGKV L +D + V VK L+A GP +
Sbjct 118 PHSDISTPLGLSRQHLSYLQEIGSGWFGKVILGEV--FSDYSPAQVVVKELRASAGPLEQ 175
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIG- 996
+ E R+L H ++++ G C + L+ME+ LG L+ YL P +
Sbjct 176 RKFISEAQPYRSLQHPNVLQCLGVCVET--LPFLLIMEFCQLGDLKRYLRAQRPPEGMSP 233
Query 997 ------LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
L L +I G+A+LH+ +Y+H DLA RN LL +D V+IGD+GLA +
Sbjct 234 ELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSN-Y 292
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYA-------SDVWSFGVTLYELL 1095
+YY E P+ W APE L E + S+VWS GVTL+EL
Sbjct 293 KEDYYLTPERLWVPLRWAAPELLGELHGSFVLVDQSRESNVWSLGVTLWELF 344
Score = 38.9 bits (89), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 60/244 (25%), Positives = 92/244 (38%), Gaps = 39/244 (16%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV- 713
F A + H ++ GVCV +++ E+ + G L +LR +R M+ ++
Sbjct 178 FISEAQPYRSLQHPNVLQCLGVCVETLPFLLIMEFCQLGDLKRYLRAQRPPEGMSPELPP 237
Query 714 --------VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+ ++A L++L + N VH ++ RN LL + +++ D GL
Sbjct 238 RDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLT-------SDLTVRIGD--YGLA 288
Query 766 ALSREERVERIP--------WLAPECLPGGANSL-----STAMDKWGFGATLLEICFDGE 812
+ +E P W APE L S S + W G TL E+ G
Sbjct 289 HSNYKEDYYLTPERLWVPLRWAAPELLGELHGSFVLVDQSRESNVWSLGVTLWELFEFGA 348
Query 813 APLQSRSPSEKEHFYQRQH-------RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
P + S E F RQ RL P + C P QRPS +
Sbjct 349 QPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCW-RPPAQRPSASDLQLQ 407
Query 866 LTRL 869
LT L
Sbjct 408 LTYL 411
>sp|A0A078CGE6|M3KE1_BRANA MAP3K epsilon protein kinase 1 OS=Brassica
napus OX=3708 GN=M3KE1 PE=1 SV=1
Length=1299
Score = 113 bits (282), Expect = 8e-24, Method: Compositional matrix adjust.
Identities = 79/269 (29%), Positives = 135/269 (50%), Gaps = 28/269 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHII 960
++G+G +G+V Y + G+ VA+K + + Q + QEID+L+ L H++I+
Sbjct 25 EIGKGAYGRV----YIGLDLENGDFVAIKQVSLENIVQEDLNTIMQEIDLLKNLNHKNIV 80
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAYLHAQ 1017
KY G + + L +++EYV GSL + + + G + + ++ Q+ EG+ YLH Q
Sbjct 81 KYLGSLKTKTH--LHIILEYVENGSLANIIKPNKFGPFPESLVTVYIAQVLEGLVYLHEQ 138
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ N+L + LVK+ DFG+A + E +P +W APE ++
Sbjct 139 GVIHRDIKGANILTTKEGLVKLADFGVATKLNEAD--VNTHSVVGTP-YWMAPEVIEMSG 195
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
ASD+WS G T+ ELLT C PP L Q + R+ + + P P
Sbjct 196 VCAASDIWSVGCTVIELLT-C----VPPYYDL------QPMPALFRIVQ----DDSPPIP 240
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
D ++ ++ C++ ++ RP + L+
Sbjct 241 DSLSPDITDFLRQCFKKDSRQRPDAKTLL 269
Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 51/210 (24%), Positives = 88/210 (42%), Gaps = 17/210 (8%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLA 719
L+ ++H ++ G ++ EYVE+G L ++ + G P + V Q+
Sbjct 70 LLKNLNHKNIVKYLGSLKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVTVYIAQVL 129
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777
L YL + ++H ++ G NIL + GL +KL+D GV + +
Sbjct 130 EGLVYLHEQGVIHRDIKGANILTTKEGL-------VKLADFGVATKLNEADVNTHSVVGT 182
Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEI--CFDGEAPLQSRSPSEKEHFYQRQHRL 833
W+APE + + + A D W G T++E+ C LQ P+ +
Sbjct 183 PYWMAPEVIE--MSGVCAASDIWSVGCTVIELLTCVPPYYDLQPM-PALFRIVQDDSPPI 239
Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
P+ P + QC + QRP +T+L
Sbjct 240 PDSLSPDITDFLRQCFKKDSRQRPDAKTLL 269
>sp|P34891|KIN15_CAEEL Receptor-like tyrosine-protein kinase kin-15
OS=Caenorhabditis elegans OX=6239 GN=kin-15 PE=2 SV=1
Length=488
Score = 110 bits (274), Expect = 8e-24, Method: Compositional matrix adjust.
Identities = 63/179 (35%), Positives = 99/179 (55%), Gaps = 17/179 (9%)
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
S+ + LL F+ QI EGM YL + +HRDLA RNVLL+ ++ ++I DFGLA+ +
Sbjct 290 SLCTSDLLSFSYQIAEGMEYLASIPCVHRDLALRNVLLNKNKTIRIADFGLARKY-QVDG 348
Query 1054 YYRVREDGDSPV--FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111
YYR+ + +P+ W APE ++E K SDVWS+GV+LYE+ + L
Sbjct 349 YYRITKGVGTPMPARWMAPEVMREGKCTEKSDVWSYGVSLYEMFS--------------L 394
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ ++ + E + +G +LP P C ++Y MK W +A+FRP+F + +
Sbjct 395 GELPYSNVSNSDVFEHVVQGNQLPMPQYCHPKMYDRMKQFWNFDATFRPSFSKCVEFFE 453
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 66/297 (22%), Positives = 123/297 (41%), Gaps = 43/297 (14%)
Query 592 LSHLGQGTRTNVYEG-RLRVEGSGDP----EEGKMDDEDPLVPGRDRGQELRVVLKVLD- 645
LS T T+ + + V+ S DP +E ++DE L+ R + ++ +
Sbjct 163 LSMRTSNTETDTLQKLSVAVKQSNDPTQENQEKMIEDETKLMCAIGRNPNILAIIGAVTA 222
Query 646 ---PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDV 697
+ + + + F E L+ + F + P++I Y+ + D
Sbjct 223 NSGSARNLLIVEFVECGDLLKFLEEKKSIFKDELVYEKNGYLLPKSIRRKTYMFNENEDD 282
Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ + + + + Q+A + YL + VH ++ RN+LL + + I++
Sbjct 283 VIEESLDSLCTSDLLSFSYQIAEGMEYLASIPCVHRDLALRNVLLNK-------NKTIRI 335
Query 758 SDPGVGLGALSREERVE---RIP----------WLAPECLPGGANSLSTAMDKWGFGATL 804
+D G L+R+ +V+ RI W+APE + G + D W +G +L
Sbjct 336 ADFG-----LARKYQVDGYYRITKGVGTPMPARWMAPEVMREGK--CTEKSDVWSYGVSL 388
Query 805 LEICFDGEAPLQSRSPSEK-EHFYQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859
E+ GE P + S S+ EH Q Q +P+ P++ Q ++ T RPSF
Sbjct 389 YEMFSLGELPYSNVSNSDVFEHVVQGNQLPMPQYCHPKMYDRMKQFWNFDATFRPSF 445
>sp|Q9SSA4|CBC1_ARATH Serine/threonine-protein kinase 54 OS=Arabidopsis
thaliana OX=3702 GN=CBC1 PE=1 SV=1
Length=411
Score = 108 bits (271), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 83/304 (27%), Positives = 134/304 (44%), Gaps = 54/304 (18%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ-HRS---------GWKQEIDILR 952
+ G FG V YD G+ VAVK L D G + HRS + QE+ +
Sbjct 114 IARGTFGTVHRGIYD------GQDVAVKLL--DWGEEGHRSDAEIASLRAAFTQEVAVWH 165
Query 953 TLYHEHIIKYKGCCEDQGEKSLQ--------------LVMEYVPLGSLRDYL---PRHSI 995
L H ++ K+ G E S+Q +V+EY P G+L+ +L R +
Sbjct 166 KLDHPNVTKFIGAAMGTSEMSIQTENGQMGMPSNVCCVVVEYCPGGALKSFLIKTRRRKL 225
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
++ + + G++YLH+Q +HRD+ N+LLD R +KI DFG+A+
Sbjct 226 AFKVVIQLSLDLARGLSYLHSQKIVHRDVKTENMLLDKSRTLKIADFGVARLEASNPNDM 285
Query 1056 RVREDGDSPVFWY-APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
G++ Y APE L + DV+SFG+ L+E+ +C P F E+
Sbjct 286 ----TGETGTLGYMAPEVLNGSPYNRKCDVYSFGICLWEI--YCCDMPYPDLSFSEVT-- 337
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ ++ + R P CP + ++MK CW+ RP E ++ +L+ +
Sbjct 338 ----------SAVVRQNLRPEIPRCCPSSLANVMKRCWDANPEKRPEMEEVVAMLEAIDT 387
Query 1175 KYQG 1178
G
Sbjct 388 SKGG 391
Score = 59.7 bits (143), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 67/239 (28%), Positives = 104/239 (44%), Gaps = 28/239 (12%)
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
QE+ V K+ P+ A T+ + Q + + VC +V EY G
Sbjct 159 QEVAVWHKLDHPNVTKFIGAAMGTSEMSIQTENGQMGMPSNVCC------VVVEYCPGGA 212
Query 695 LDVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752
L +L + R +A+K+V+ + LA LSYL ++ +VH +V N+LL + S
Sbjct 213 LKSFLIKTR-RRKLAFKVVIQLSLDLARGLSYLHSQKIVHRDVKTENMLLDK-------S 264
Query 753 PFIKLSDPGVGLGALSREERVE----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI- 807
+K++D GV S + + ++APE L G + + D + FG L EI
Sbjct 265 RTLKIADFGVARLEASNPNDMTGETGTLGYMAPEVLNG--SPYNRKCDVYSFGICLWEIY 322
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSC--PQLATLTSQCLTYEPTQRPSFRTIL 863
C D P S SE RQ+ PE P C LA + +C P +RP ++
Sbjct 323 CCD--MPYPDLSFSEVTSAVVRQNLRPEIPRCCPSSLANVMKRCWDANPEKRPEMEEVV 379
>sp|Q65XV8|RK176_ORYSJ Receptor-like cytoplasmic kinase 176 OS=Oryza
sativa subsp. japonica OX=39947 GN=RLCK176 PE=1 SV=1
Length=395
Score = 108 bits (269), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 97/301 (32%), Positives = 143/301 (48%), Gaps = 29/301 (10%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LGEG FG V D PT GTG ++AVK L + HR W E++ L L H
Sbjct 76 LGEGGFGSVFKGWIDEKTLAPTKPGTGMVIAVKKLNQEGHQGHRE-WLAEVNYLGQLSHP 134
Query 958 HIIKYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGM 1011
++++ G C ED E+ L LV E++P GSL ++L R S L + A +G+
Sbjct 135 YLVRLVGYCVED--EQRL-LVYEFMPRGSLENHLFRRSTHFQPLSWNLRMKIALGAAKGL 191
Query 1012 AYLHAQHY--IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
A+LH+ I+RD NVLLD + K+ DFGLAK P G + + V + A
Sbjct 192 AFLHSDKVKVIYRDFKTSNVLLDANYDAKLSDFGLAKDGPTGDKSH-VSTRVMGTYGYAA 250
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQ----GQMTVLRL 1124
PE L SDV+SFGV L E+L+ + ++ PT L+ A+ + + R+
Sbjct 251 PEYLATGHLTTKSDVYSFGVVLLEMLSGRRALDKNRPTGEHNLVEWARPYLMSKRRIFRI 310
Query 1125 TELLERGE-RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE-KYQGQAPS 1182
+ G+ L + K L C EA RP E ++ +L+ + + K G P
Sbjct 311 LDARLGGQYSLAKAQKAAT----LALQCISVEAKNRPNMEQVVAVLEQLQDSKETGANPQ 366
Query 1183 V 1183
+
Sbjct 367 L 367
Score = 62.0 bits (149), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 75/322 (23%), Positives = 133/322 (41%), Gaps = 45/322 (14%)
Query 575 NLSQLSFH--RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
N+ +F+ R + S LG+G +V++G + DE L P +
Sbjct 54 NVKAFAFNELRTATRNFRPDSVLGEGGFGSVFKGWI--------------DEKTLAPTKP 99
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
G + + +K L+ H + + + Q+SH +L + G CV + ++V E++
Sbjct 100 -GTGMVIAVKKLNQEGHQGHREWLAEVNYLGQLSHPYLVRLVGYCVEDEQRLLVYEFMPR 158
Query 693 GPLDVWLRRERGHV-PMAW--KMVVAQQLASALSYL--ENKNLVHGNVCGRNILLARLGL 747
G L+ L R H P++W +M +A A L++L + +++ + N+LL
Sbjct 159 GSLENHLFRRSTHFQPLSWNLRMKIALGAAKGLAFLHSDKVKVIYRDFKTSNVLLDANYD 218
Query 748 AEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
A+ S F D G + + + APE L G L+T D + FG LLE+
Sbjct 219 AK-LSDFGLAKDGPTGDKSHVSTRVMGTYGYAAPEYLATG--HLTTKSDVYSFGVVLLEM 275
Query 808 CFDGEAPLQSRSPSEKEHFYQ----------RQHRLPE---------PSCPQLATLTSQC 848
G L P+ + + + R R+ + + ATL QC
Sbjct 276 -LSGRRALDKNRPTGEHNLVEWARPYLMSKRRIFRILDARLGGQYSLAKAQKAATLALQC 334
Query 849 LTYEPTQRPSFRTILRDLTRLQ 870
++ E RP+ ++ L +LQ
Sbjct 335 ISVEAKNRPNMEQVVAVLEQLQ 356
>sp|Q54R82|MKKA_DICDI Mitogen-activated protein kinase kinase
kinase A OS=Dictyostelium discoideum OX=44689 GN=mkkA PE=1 SV=2
Length=942
Score = 112 bits (279), Expect = 1e-23, Method: Compositional matrix adjust.
Identities = 79/295 (27%), Positives = 144/295 (49%), Gaps = 33/295 (11%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA---DCGPQHRS---GWKQ 946
H +K + LG G +G V Y N TGE+ AVK L+ + P+ ++ + +
Sbjct 166 HNIKWQKGQILGRGGYGSV----YLGLNKDTGELFAVKQLEIVDINSDPKLKNMILSFSK 221
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL-LFAQ 1005
EI+++R+L H++I++Y G DQ L + +EY+P GS+ L + ++ ++ +
Sbjct 222 EIEVMRSLRHDNIVRYLGTSLDQS--FLSVFLEYIPGGSISSLLGKFGAFSENVIKVYTK 279
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
QI +G+++LHA IHRD+ N+L+D +VK+ DFG +K+ ++ + +P
Sbjct 280 QILQGLSFLHANSIIHRDIKGANILIDTKGIVKLSDFGCSKSFSGIVSQFKSMQ--GTP- 336
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+W APE +K+ +SD+WS G + E+ T +Q P + EL +
Sbjct 337 YWMAPEVIKQTGHGRSSDIWSLGCVIVEMAT----AQPPWSNITELAAVMYH-------- 384
Query 1126 ELLERGERLPR-PDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQ 1177
+ +P P E + + C++ + RP L+ P + + + Q
Sbjct 385 --IASSNSIPNIPSHMSQEAFDFLNLCFKRDPKERPDANQLLKHPFIMNLDDNIQ 437
Score = 54.7 bits (130), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 55/242 (23%), Positives = 101/242 (42%), Gaps = 27/242 (11%)
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
++L +V DP ++ L+F + +M + H ++ G + + EY+ G
Sbjct 199 KQLEIVDINSDPKLKNMILSFSKEIEVMRSLRHDNIVRYLGTSLDQSFLSVFLEYIPGGS 258
Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+ L + K V +Q+ LS+L +++H ++ G NIL+ G+
Sbjct 259 ISSLLGKFGAFSENVIK-VYTKQILQGLSFLHANSIIHRDIKGANILIDTKGI------- 310
Query 755 IKLSDPGVGL---GALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+KLSD G G +S+ + ++ P W+APE + + S+ D W G ++E+
Sbjct 311 VKLSDFGCSKSFSGIVSQFKSMQGTPYWMAPEVIKQTGHGRSS--DIWSLGCVIVEM--- 365
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ--------CLTYEPTQRPSFRTI 862
A Q + E H S P + + SQ C +P +RP +
Sbjct 366 --ATAQPPWSNITELAAVMYHIASSNSIPNIPSHMSQEAFDFLNLCFKRDPKERPDANQL 423
Query 863 LR 864
L+
Sbjct 424 LK 425
>sp|F4HRJ4|M3K3A_ARATH Mitogen-activated protein kinase kinase
kinase 3 OS=Arabidopsis thaliana OX=3702 GN=MAPKKK3 PE=1 SV=1
Length=609
Score = 110 bits (275), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 84/295 (28%), Positives = 141/295 (48%), Gaps = 32/295 (11%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS----GWKQEIDILRT 953
KK + LG G FG+V Y N G+M A+K +K Q QEI++L
Sbjct 215 KKGKFLGSGTFGQV----YLGFNSEKGKMCAIKEVKVISDDQTSKECLKQLNQEINLLNQ 270
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012
L H +I++Y G + E++L + +EYV GS+ L + S + + +QI G+A
Sbjct 271 LCHPNIVQYYG--SELSEETLSVYLEYVSGGSIHKLLKDYGSFTEPVIQNYTRQILAGLA 328
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE- 1071
YLH ++ +HRD+ N+L+D + +K+ DFG+AK V + + SP +W APE
Sbjct 329 YLHGRNTVHRDIKGANILVDPNGEIKLADFGMAKHV---TAFSTMLSFKGSP-YWMAPEV 384
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + + +A D+WS G T+ E+ T S+ P ++F +G + ++ +
Sbjct 385 VMSQNGYTHAVDIWSLGCTILEMAT----SKPPWSQF-------EGVAAIFKIGNSKDTP 433
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAPSVF 1184
E PD + + ++ C + + RPT L+ P L+ P F
Sbjct 434 E---IPDHLSNDAKNFIRLCLQRNPTVRPTASQLLEHPFLRNTTRVASTSLPKDF 485
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 72/296 (24%), Positives = 121/296 (41%), Gaps = 50/296 (17%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LG GT VY G + E+GKM +E++V+ D + +
Sbjct 220 LGSGTFGQVYLGF-------NSEKGKMCAI----------KEVKVISD--DQTSKECLKQ 260
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
+ +L++Q+ H ++ +G + + EYV G + L+ + G
Sbjct 261 LNQEINLLNQLCHPNIVQYYGSELSEETLSVYLEYVSGGSIHKLLK-DYGSFTEPVIQNY 319
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREER 772
+Q+ + L+YL +N VH ++ G NIL+ G IKL+D G+ + A S
Sbjct 320 TRQILAGLAYLHGRNTVHRDIKGANILVDPNGE-------IKLADFGMAKHVTAFSTMLS 372
Query 773 VERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEIC--------FDGEAPLQSRSPSEK 823
+ P W+APE + N + A+D W G T+LE+ F+G A + S+
Sbjct 373 FKGSPYWMAPEVV-MSQNGYTHAVDIWSLGCTILEMATSKPPWSQFEGVAAIFKIGNSKD 431
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI-----LRDLTRLQPHNL 874
+P+ CL PT RP+ + LR+ TR+ +L
Sbjct 432 ------TPEIPDHLSNDAKNFIRLCLQRNPTVRPTASQLLEHPFLRNTTRVASTSL 481
>sp|Q95UN8|M3KSL_DROME Mitogen-activated protein kinase kinase
kinase OS=Drosophila melanogaster OX=7227 GN=slpr PE=1 SV=1
Length=1161
Score = 112 bits (279), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 95/284 (33%), Positives = 129/284 (45%), Gaps = 43/284 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVK---ALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G G F KV YD GE VA+K D + R QE + L HE+I
Sbjct 148 IGSGGFCKVHRGYYD------GEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKHENI 201
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
+G C + L LVMEY GSL L I L+ +A QI GM YLH +
Sbjct 202 AALRGVCLN---TKLCLVMEYARGGSLNRILA-GKIPPDVLVNWAIQIARGMNYLHNEAP 257
Query 1018 -HYIHRDLAARNVLLD--------NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
IHRDL + NVL+ + +KI DFGLA+ + Y R W
Sbjct 258 MSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREM-----YNTQRMSAAGTYAWM 312
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE + + SDVWS+GV L+EL+T P K + + +A G + V LT
Sbjct 313 PPEVISVSTYSKFSDVWSYGVLLWELIT-----GETPYKGFDPLSVAYG-VAVNTLT--- 363
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
LP P CP LMK+CW+T+ RP F+ ++ L+++
Sbjct 364 -----LPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESI 402
>sp|Q8AXB3|VGFR4_DANRE Vascular endothelial growth factor receptor
kdr-like OS=Danio rerio OX=7955 GN=kdrl PE=1 SV=1
Length=1302
Score = 111 bits (278), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 65/177 (37%), Positives = 98/177 (55%), Gaps = 14/177 (8%)
Query 990 LPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
L + + L L+ ++ Q+ +GM +L ++ IHRDLAARN+LL + +VKI DFGLA+ V
Sbjct 970 LYKKVLTLEDLICYSFQVAKGMEFLASRKCIHRDLAARNILLSENNVVKICDFGLARDVY 1029
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
+ +Y R + D P+ W APE + + + SDVWSFGV ++E+ + +S P
Sbjct 1030 KDPDYVR-KGDARLPLKWMAPEAIFDKIYTTQSDVWSFGVLMWEIFS-LGASPYP----- 1082
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
G+ + RL E G R+ P+ E+Y M +CW E S RPTF L+
Sbjct 1083 ---GLHIDEEFCCRLKE----GTRMKAPEYSSSEIYQTMLDCWHGEPSQRPTFTELV 1132
Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 41/164 (25%), Positives = 71/164 (43%), Gaps = 22/164 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V +
Sbjct 986 QVAKGMEFLASRKCIHRDLAARNILLSENNV-------VKICDFGLARDVYKDPDYVRKG 1038
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + +T D W FG + EI G +P E+ F R
Sbjct 1039 DARLPLKWMAPEAIFDKI--YTTQSDVWSFGVLMWEIFSLGASPYPGLHIDEE--FCCRL 1094
Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + PE S ++ C EP+QRP+F ++ L L
Sbjct 1095 KEGTRMKAPEYSSSEIYQTMLDCWHGEPSQRPTFTELVERLGDL 1138
>sp|Q0CL79|SEPH_ASPTN Cytokinesis protein sepH OS=Aspergillus
terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=sepH PE=3
SV=2
Length=1342
Score = 111 bits (278), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 73/199 (37%), Positives = 104/199 (52%), Gaps = 24/199 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V Y N TGE VAVK +K P +S + EID+L+ L H +I+KY
Sbjct 67 LGKGAFGSV----YRALNWNTGETVAVKQIKLADLP--KSELRLEIDLLKNLDHPNIVKY 120
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDY------LPRHSIGLAQLLLFAQQICEGMAYLHA 1016
+G + ++L +++EY GSL P + +GL + Q+ G+ YLH
Sbjct 121 QGFV--KSAETLNIILEYCENGSLHSIAKNFGRFPENLVGL-----YMSQVLHGLLYLHE 173
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
Q IHRD+ N+L + LVK+ DFG+A E V +P +W APE ++
Sbjct 174 QGVIHRDIKGANILTTKEGLVKLADFGVASRTTGLSESSVV----GTP-YWMAPEVIELS 228
Query 1077 KFYYASDVWSFGVTLYELL 1095
ASD+WS G T+ ELL
Sbjct 229 GATTASDIWSLGCTVIELL 247
Score = 63.2 bits (152), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 56/209 (27%), Positives = 90/209 (43%), Gaps = 17/209 (8%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
L+ + H ++ G ++ EY E+G L + + G P + Q+
Sbjct 108 LLKNLDHPNIVKYQGFVKSAETLNIILEYCENGSLHS-IAKNFGRFPENLVGLYMSQVLH 166
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIPW 778
L YL + ++H ++ G NIL + GL +KL+D GV LS V W
Sbjct 167 GLLYLHEQGVIHRDIKGANILTTKEGL-------VKLADFGVASRTTGLSESSVVGTPYW 219
Query 779 LAPECLP-GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQH-RLPE 835
+APE + GA +TA D W G T++E+ +G+ P + P H LP+
Sbjct 220 MAPEVIELSGA---TTASDIWSLGCTVIEL-LEGKPPYYNMQPMPALFRIVNDDHPPLPQ 275
Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ P + QC +P R S R +L+
Sbjct 276 GASPAVKDFLMQCFQKDPNLRVSARKLLK 304
>sp|Q9FZ36|M3K2_ARATH Mitogen-activated protein kinase kinase
kinase 2 OS=Arabidopsis thaliana OX=3702 GN=ANP2 PE=2 SV=1
Length=651
Score = 110 bits (275), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 77/294 (26%), Positives = 145/294 (49%), Gaps = 32/294 (11%)
Query 884 SPASDPTVFHKRYLK--KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA--LKADCGPQ 939
SP ++ TV K ++ K + +G G FG V Y N +GE++AVK + ++C +
Sbjct 53 SPPNNSTVQIKPPIRWRKGQLIGRGAFGTV----YMGMNLDSGELLAVKQVLITSNCASK 108
Query 940 HRSG-----WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993
++ ++E+ +L+ L H +I++Y G + +++L +++E+VP GS+ L +
Sbjct 109 EKTQAHIQELEEEVKLLKNLSHPNIVRYLGTVRE--DETLNILLEFVPGGSISSLLEKFG 166
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ + + + Q+ G+ YLH +HRD+ N+L+DN +K+ DFG +K V E
Sbjct 167 AFPESVVRTYTNQLLLGLEYLHNHAIMHRDIKGANILVDNQGCIKLADFGASKQVAELAT 226
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELI 1112
+ +P +W APE + + +++D+WS G T+ E++T ++P ++ E+
Sbjct 227 ISGAKSMKGTP-YWMAPEVILQTGHSFSADIWSVGCTVIEMVT----GKAPWSQQYKEIA 281
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
I T P PD + + C + E + RPT L+
Sbjct 282 AIFHIGTT----------KSHPPIPDNISSDANDFLLKCLQQEPNLRPTASELL 325
Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 58/219 (26%), Positives = 95/219 (43%), Gaps = 23/219 (11%)
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715
E L+ +SH ++ G VR E + ++ E+V G + L + G P +
Sbjct 120 EEVKLLKNLSHPNIVRYLGT-VREDETLNILLEFVPGGSISSLLEK-FGAFPESVVRTYT 177
Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-----LGALSRE 770
QL L YL N ++H ++ G NIL+ G IKL+D G L +S
Sbjct 178 NQLLLGLEYLHNHAIMHRDIKGANILVDNQGC-------IKLADFGASKQVAELATISGA 230
Query 771 ERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-- 827
+ ++ P W+APE + +S S D W G T++E+ G+AP + F+
Sbjct 231 KSMKGTPYWMAPEVILQTGHSFSA--DIWSVGCTVIEM-VTGKAPWSQQYKEIAAIFHIG 287
Query 828 -QRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ H +P+ +CL EP RP+ +L+
Sbjct 288 TTKSHPPIPDNISSDANDFLLKCLQQEPNLRPTASELLK 326
>sp|Q61083|M3K2_MOUSE Mitogen-activated protein kinase kinase
kinase 2 OS=Mus musculus OX=10090 GN=Map3k2 PE=1 SV=2
Length=619
Score = 110 bits (274), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 67/201 (33%), Positives = 106/201 (53%), Gaps = 13/201 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ------EIDILRTLYH 956
LG+G FG+V L CYD TG +AVK ++ + P+ K+ EI +L+ L H
Sbjct 362 LGQGAFGRVYL-CYDV---DTGRELAVKQVQFN--PESPETSKEVNALECEIQLLKNLLH 415
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL-LFAQQICEGMAYLH 1015
E I++Y GC D EK+L + ME P GS++D L + + + +QI EG+ YLH
Sbjct 416 ERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLH 475
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ +HRD+ N+L D+ +K+GDFG +K + + +W +PE +
Sbjct 476 SNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISG 535
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
+ +D+WS T+ E+LT
Sbjct 536 EGYGRKADIWSVACTVVEMLT 556
Score = 34.7 bits (78), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 43/192 (22%), Positives = 75/192 (39%), Gaps = 30/192 (16%)
Query 632 DRGQELRVVLKVLDPSHHDIAL---AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
D G+EL V +P + + A L+ + H + +G C+R P+ ++
Sbjct 377 DTGRELAVKQVQFNPESPETSKEVNALECEIQLLKNLLHERIVQYYG-CLRDPQEKTLSI 435
Query 689 YVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
++E P + + + + + +Q+ + YL + +VH ++ G NIL G
Sbjct 436 FMELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTG 495
Query 747 LAEGTSPFIKLSDPGV----------GLGALSREERVERIP-WLAPECLPGGANSLSTAM 795
IKL D G G G S V P W++PE + G
Sbjct 496 -------NIKLGDFGASKRLQTICLSGTGMKS----VTGTPYWMSPEVISG--EGYGRKA 542
Query 796 DKWGFGATLLEI 807
D W T++E+
Sbjct 543 DIWSVACTVVEM 554
>sp|Q96Q04|LMTK3_HUMAN Serine/threonine-protein kinase LMTK3 OS=Homo
sapiens OX=9606 GN=LMTK3 PE=1 SV=2
Length=1460
Score = 111 bits (278), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 77/227 (34%), Positives = 115/227 (51%), Gaps = 23/227 (10%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
+ P +++L ++++G G FGKV L +D T V VK L+A GP + +
Sbjct 123 TTPLGLSRQHLSYLQEIGSGWFGKVILGEI--FSDYTPAQVVVKELRASAGPLEQRKFIS 180
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLA------ 998
E R+L H ++++ G C + L+ME+ LG L+ YL R GL+
Sbjct 181 EAQPYRSLQHPNVLQCLGLCVET--LPFLLIMEFCQLGDLKRYLRAQRPPEGLSPELPPR 238
Query 999 ---QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
L +I G+A+LH+ +Y+H DLA RN LL +D V+IGD+GLA + +YY
Sbjct 239 DLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSN-YKEDYY 297
Query 1056 RVREDGDSPVFWYAPECLKEYKFYY-------ASDVWSFGVTLYELL 1095
E P+ W APE L E + S++WS GVTL+EL
Sbjct 298 LTPERLWIPLRWAAPELLGELHGTFMVVDQSRESNIWSLGVTLWELF 344
Score = 37.0 bits (84), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 63/263 (24%), Positives = 102/263 (39%), Gaps = 42/263 (16%)
Query 638 RVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+VV+K L S + F A + H ++ G+CV +++ E+ + G L
Sbjct 160 QVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLK 219
Query 697 VWLRRERGHVPMAWKMV---------VAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
+LR +R ++ ++ + ++A L++L + N VH ++ RN LL
Sbjct 220 RYLRAQRPPEGLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLT---- 275
Query 748 AEGTSPFIKLSDPGVGLGALSREERVERIP--------WLAPECLPGGANSLSTAMDK-- 797
+ +++ D GL + +E P W APE L G + +D+
Sbjct 276 ---SDLTVRIGD--YGLAHSNYKEDYYLTPERLWIPLRWAAPELL-GELHGTFMVVDQSR 329
Query 798 ----WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH-------RLPEPSCPQLATLTS 846
W G TL E+ G P + S E F RQ RL P +
Sbjct 330 ESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQ 389
Query 847 QCLTYEPTQRPSFRTILRDLTRL 869
C P QRPS + LT L
Sbjct 390 SCW-RPPAQRPSASDLQLQLTYL 411
>sp|Q54Y55|SHKC_DICDI Dual specificity protein kinase shkC OS=Dictyostelium
discoideum OX=44689 GN=shkC PE=3 SV=1
Length=506
Score = 108 bits (271), Expect = 3e-23, Method: Compositional matrix adjust.
Identities = 82/277 (30%), Positives = 133/277 (48%), Gaps = 31/277 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FGKV + VAVK L K + S +++E+ ++ +YH +I
Sbjct 30 IGTGSFGKVY------KGRCRQKAVAVKLLHKQNFDAATLSAFRKEVHLMSKIYHPNICL 83
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLF--AQQICEGMAYLHAQH- 1018
+ G C G +V E VP G+L L I L L A+ G+ +LH +
Sbjct 84 FMGACTIPGR--CVIVTELVPKGNLETLLHDQKIQLPLYLRMRMARDAALGINWLHESNP 141
Query 1019 -YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
++HRD+ + N+L+D + VKI DFGL+ A+ + H+ + + + APE + +
Sbjct 142 VFVHRDIKSSNLLVDENMRVKICDFGLS-ALKQKHKMLKDQSSAKGTPLYMAPEVMMFKE 200
Query 1078 FYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
F +SDV+SFG+ L+E+LT + S KF E + + + ER P
Sbjct 201 FNESSDVYSFGIVLWEILTRKEPFSHHRELEKFREAVCV---------------KHERPP 245
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P+ C + L++ CW+ E RP+F+ +I L V
Sbjct 246 IPNDCLDSLRRLIEKCWDKEPISRPSFKEIISALDHV 282
Score = 68.6 bits (166), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 65/252 (26%), Positives = 112/252 (44%), Gaps = 28/252 (11%)
Query 631 RDRGQELRVVLKVLDPSHHDIAL--AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+ R ++ V +K+L + D A AF + LMS++ H ++ G C ++VTE
Sbjct 40 KGRCRQKAVAVKLLHKQNFDAATLSAFRKEVHLMSKIYHPNICLFMGACTIPGRCVIVTE 99
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLG 746
V G L+ L ++ +P+ +M +A+ A +++L N VH ++ N+L+
Sbjct 100 LVPKGNLETLLHDQKIQLPLYLRMRMARDAALGINWLHESNPVFVHRDIKSSNLLVDE-- 157
Query 747 LAEGTSPFIKLSDPGVGLGALSREERVERIP--------WLAPECLPGGANSLSTAMDKW 798
+ +K+ D GL AL ++ ++ + ++APE + + + D +
Sbjct 158 -----NMRVKICD--FGLSALKQKHKMLKDQSSAKGTPLYMAPEVM--MFKEFNESSDVY 208
Query 799 GFGATLLEICFDGEAPLQSRSPSEK--EHFYQRQHRLPEPS--CPQLATLTSQCLTYEPT 854
FG L EI E P EK E + R P P+ L L +C EP
Sbjct 209 SFGIVLWEILTRKE-PFSHHRELEKFREAVCVKHERPPIPNDCLDSLRRLIEKCWDKEPI 267
Query 855 QRPSFRTILRDL 866
RPSF+ I+ L
Sbjct 268 SRPSFKEIISAL 279
>sp|P52583|VGFR2_COTJA Vascular endothelial growth factor receptor
2 OS=Coturnix japonica OX=93934 GN=KDR PE=1 SV=1
Length=1348
Score = 111 bits (277), Expect = 3e-23, Method: Compositional matrix adjust.
Identities = 62/177 (35%), Positives = 96/177 (54%), Gaps = 14/177 (8%)
Query 990 LPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
L ++ + + L+ ++ Q+ GM +L ++ IHRDLAARN+LL ++ +VKI DFGLA+ +
Sbjct 988 LCKNPLTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLSDNNVVKICDFGLARDIY 1047
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
+ +Y R + D P+ W APE + + + SDVWSFGV L+E+ + +S P K
Sbjct 1048 KDPDYVR-KGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFS-LGASPYPGVKID 1105
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
E L+ G R+ PD E+Y M +CW + RPTF L+
Sbjct 1106 E------------EFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGDPKQRPTFSELV 1150
Score = 53.1 bits (126), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 43/171 (25%), Positives = 76/171 (44%), Gaps = 26/171 (15%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V +
Sbjct 1004 QVARGMEFLASRKCIHRDLAARNILLS-------DNNVVKICDFGLARDIYKDPDYVRKG 1056
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--EHFYQ 828
+ W+APE + ++ + D W FG L EI G +P P K E F +
Sbjct 1057 DARLPLKWMAPETIFDRVYTIQS--DVWSFGVLLWEIFSLGASPY----PGVKIDEEFCR 1110
Query 829 R-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
R + R P+ + P++ C +P QRP+F ++ L L N+
Sbjct 1111 RLKEGTRMRAPDYTTPEMYQTMLDCWHGDPKQRPTFSELVEHLGNLLQANV 1161
>sp|P41892|CDC7_SCHPO Cell division control protein 7 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=cdc7
PE=1 SV=1
Length=1062
Score = 110 bits (276), Expect = 3e-23, Method: Compositional matrix adjust.
Identities = 73/195 (37%), Positives = 102/195 (52%), Gaps = 13/195 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG+G FG V Y N GE VAVK +K + S K EID+L+ L H +I+K
Sbjct 15 LGKGAFGAV----YRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVK 70
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYI 1020
Y+G Q SL +++EY GSLR I + L+ Q+ +G+ YLH Q I
Sbjct 71 YRGSY--QTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLLYLHNQGVI 128
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ N+L D +K+ DFG+A + ++ V SP +W APE ++
Sbjct 129 HRDIKGANILTTKDGTIKLADFGVATKINALEDHSVV----GSP-YWMAPEVIELVGATT 183
Query 1081 ASDVWSFGVTLYELL 1095
ASD+WS G T+ ELL
Sbjct 184 ASDIWSVGCTVIELL 198
Score = 65.5 bits (158), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 58/209 (28%), Positives = 91/209 (44%), Gaps = 17/209 (8%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
L+ + H ++ G ++ EY E+G L + + G +P + Q+
Sbjct 59 LLKNLDHPNIVKYRGSYQTNDSLCIILEYCENGSLRS-ICKNFGKIPENLVALYTFQVLQ 117
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIPW 778
L YL N+ ++H ++ G NIL + +GT IKL+D GV + AL V W
Sbjct 118 GLLYLHNQGVIHRDIKGANILTTK----DGT---IKLADFGVATKINALEDHSVVGSPYW 170
Query 779 LAPECLP-GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS 837
+APE + GA +TA D W G T++E+ DG P P+ + P PS
Sbjct 171 MAPEVIELVGA---TTASDIWSVGCTVIEL-LDGNPPYYDLDPTSALFRMVKDEHPPLPS 226
Query 838 CPQLA--TLTSQCLTYEPTQRPSFRTILR 864
A + QC +P R R +L+
Sbjct 227 NISSAAKSFLMQCFQKDPNLRIKTRKLLK 255
>sp|Q9ASQ5|CRCK3_ARATH Calmodulin-binding receptor-like cytoplasmic
kinase 3 OS=Arabidopsis thaliana OX=3702 GN=CRCK3 PE=2
SV=1
Length=510
Score = 108 bits (270), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 66/200 (33%), Positives = 103/200 (52%), Gaps = 13/200 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG V D G++VA+K K + R+ +K E+D+L + H +++K
Sbjct 231 IGEGGFGVVFKGVLD-----DGQVVAIKRAKKEHFENLRTEFKSEVDLLSKIGHRNLVKL 285
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHA--- 1016
G D+G++ L ++ EYV G+LRD+L + Q L +C G+ YLH+
Sbjct 286 LGYV-DKGDERL-IITEYVRNGTLRDHLDGARGTKLNFNQRLEIVIDVCHGLTYLHSYAE 343
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ IHRD+ + N+LL + K+ DFG A+ P + V + PE +K Y
Sbjct 344 RQIIHRDIKSSNILLTDSMRAKVADFGFARGGPTDSNQTHILTQVKGTVGYLDPEYMKTY 403
Query 1077 KFYYASDVWSFGVTLYELLT 1096
SDV+SFG+ L E+LT
Sbjct 404 HLTAKSDVYSFGILLVEILT 423
Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 51/205 (25%), Positives = 90/205 (44%), Gaps = 25/205 (12%)
Query 632 DRGQELRVVLKVLDPSH-HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
D GQ V +K H ++ F L+S++ H +L + G +G E +++TEYV
Sbjct 245 DDGQV--VAIKRAKKEHFENLRTEFKSEVDLLSKIGHRNLVKLLGYVDKGDERLIITEYV 302
Query 691 EHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLG 746
+G L L RG + ++ + + L+YL + + ++H ++ NILL
Sbjct 303 RNGTLRDHLDGARGTKLNFNQRLEIVIDVCHGLTYLHSYAERQIIHRDIKSSNILLT--- 359
Query 747 LAEGTSPFIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWG 799
S K++D G G + + + +L PE + L+ D +
Sbjct 360 ----DSMRAKVADFGFARGGPTDSNQTHILTQVKGTVGYLDPEYMK--TYHLTAKSDVYS 413
Query 800 FGATLLEICFDGEAPLQS-RSPSEK 823
FG L+EI G P+++ R P E+
Sbjct 414 FGILLVEI-LTGRRPVEAKRLPDER 437
>sp|Q40541|NPK1_TOBAC Mitogen-activated protein kinase kinase
kinase NPK1 OS=Nicotiana tabacum OX=4097 GN=NPK1 PE=1 SV=1
Length=690
Score = 109 bits (273), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 75/283 (27%), Positives = 134/283 (47%), Gaps = 30/283 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-------DCGPQHRSGWKQEIDILRTLY 955
+G G FG+V Y N +GE++A+K + + H ++E+++L+ L
Sbjct 86 IGCGAFGRV----YMGMNVDSGELLAIKEVSIAMNGASRERAQAHVRELEEEVNLLKNLS 141
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYL 1014
H +I++Y G + G SL +++E+VP GS+ L + S + + ++ +Q+ G+ YL
Sbjct 142 HPNIVRYLGTAREAG--SLNILLEFVPGGSISSLLGKFGSFPESVIRMYTKQLLLGLEYL 199
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H +HRD+ N+L+DN +K+ DFG +K V E + +P +W APE +
Sbjct 200 HKNGIMHRDIKGANILVDNKGCIKLADFGASKKVVELATMTGAKSMKGTP-YWMAPEVIL 258
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ +++D+WS G T+ E+ T PP +Q V L +
Sbjct 259 QTGHSFSADIWSVGCTIIEMATG-----KPP--------WSQQYQEVAALFHIGTTKSHP 305
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEK 1175
P P+ E + C + E R + NL+ P + H++
Sbjct 306 PIPEHLSAESKDFLLKCLQKEPHLRHSASNLLQHPFVTAEHQE 348
Score = 50.8 bits (120), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 54/218 (25%), Positives = 93/218 (43%), Gaps = 21/218 (10%)
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
E +L+ +SH ++ G ++ E+V G + L + G P + + +
Sbjct 132 EEVNLLKNLSHPNIVRYLGTAREAGSLNILLEFVPGGSISSLLGK-FGSFPESVIRMYTK 190
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-----VGLGALSREE 771
QL L YL ++H ++ G NIL+ G IKL+D G V L ++ +
Sbjct 191 QLLLGLEYLHKNGIMHRDIKGANILVDNKGC-------IKLADFGASKKVVELATMTGAK 243
Query 772 RVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--- 827
++ P W+APE + +S S D W G T++E+ G+ P + F+
Sbjct 244 SMKGTPYWMAPEVILQTGHSFSA--DIWSVGCTIIEMA-TGKPPWSQQYQEVAALFHIGT 300
Query 828 QRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ H +PE + +CL EP R S +L+
Sbjct 301 TKSHPPIPEHLSAESKDFLLKCLQKEPHLRHSASNLLQ 338
>sp|P28829|BYR2_SCHPO Protein kinase byr2 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=byr2 PE=1 SV=1
Length=659
Score = 109 bits (273), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 68/218 (31%), Positives = 108/218 (50%), Gaps = 23/218 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-------GWKQEIDILRTLY 955
+G G FG+V Y N +GE++AVK + D + + EI +L+ L
Sbjct 400 IGSGSFGQV----YLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELS 455
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYL 1014
HEHI++Y G + L + +EYVP GS+ L + S + F +Q +G+ YL
Sbjct 456 HEHIVQYLGS--NLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYL 513
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV---REDGDSPVFWYAPE 1071
H++ +HRD+ N+L+DN +KI DFG++K + + R FW APE
Sbjct 514 HSRGIVHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPE 573
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT------HCDSSQS 1103
+K+ +D+WS G + E+LT +CD Q+
Sbjct 574 VVKQTMHTEKTDIWSLGCLVIEMLTSKHPYPNCDQMQA 611
Score = 40.8 bits (94), Expect = 0.088, Method: Compositional matrix adjust.
Identities = 42/170 (25%), Positives = 69/170 (41%), Gaps = 20/170 (12%)
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
H + A +L+ ++SH H+ G + + EYV G + L
Sbjct 437 HAKLLDALAGEIALLQELSHEHIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEE 496
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---- 763
K + Q L L YL ++ +VH ++ G NIL+ G IK+SD G+
Sbjct 497 TLVKNFIKQTLK-GLEYLHSRGIVHRDIKGANILVDNKGK-------IKISDFGISKKLE 548
Query 764 LGALSREERVERIP------WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
L + S + R W+APE + ++ T D W G ++E+
Sbjct 549 LNSTSTKTGGARPSFQGSSFWMAPEVVKQTMHTEKT--DIWSLGCLVIEM 596
>sp|P79750|CSF11_TAKRU Macrophage colony-stimulating factor 1
receptor 1 OS=Takifugu rubripes OX=31033 GN=csf1r1 PE=3 SV=1
Length=975
Score = 110 bits (274), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 60/169 (36%), Positives = 99/169 (59%), Gaps = 16/169 (9%)
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ + LL F+ Q+ +G+ +L +++ IHRD+AARNVLL + R+ KI DFGLA+ + Y
Sbjct 754 LDIDDLLRFSLQVAQGLDFLASRNCIHRDVAARNVLLTDKRVAKICDFGLARDIMNDSNY 813
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIG 1113
V+ + PV W APE + + + SDVWS+G+ L+E+ + +SP P+ ++
Sbjct 814 V-VKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFS---LGKSPYPSMAVD--- 866
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
R ++++RG ++ +PD E+Y +MK CW E + RPTF
Sbjct 867 --------SRFYKMVKRGYQMSQPDFALPEIYMIMKMCWNLEPTERPTF 907
Score = 65.9 bits (159), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 44/164 (27%), Positives = 81/164 (49%), Gaps = 22/164 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A L +L ++N +H +V RN+LL +A K+ D G+ ++ V +
Sbjct 765 QVAQGLDFLASRNCIHRDVAARNVLLTDKRVA-------KICDFGLARDIMNDSNYVVKG 817
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-- 828
+ W+APE + ++ + D W +G L EI G++P S + + FY+
Sbjct 818 NARLPVKWMAPESIFDCVYTVQS--DVWSYGILLWEIFSLGKSPYPSMAVDSR--FYKMV 873
Query 829 -RQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
R +++ +P + P++ + C EPT+RP+F I + + RL
Sbjct 874 KRGYQMSQPDFALPEIYMIMKMCWNLEPTERPTFSMISQMINRL 917
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 47/168 (28%), Positives = 76/168 (45%), Gaps = 17/168 (10%)
Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS-PASDPTVFHKRYLKKIRDLGEGHFG 909
Y+ Q+P F + + + +N ++P P ++ F + LK + LG G FG
Sbjct 540 YKYKQKPRFEIRWKIIEAREGNNYT---FIDPTQLPYNEKWEFPRDKLKLGKVLGAGAFG 596
Query 910 KVSLYCYDPTNDGTGE------MVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKY 962
KV + T G GE VAVK LKA+ R E+ IL L +H++I+
Sbjct 597 KV----VEATAFGLGEDKDNTLRVAVKMLKANAHSDEREALMSELKILSHLGHHQNIVNL 652
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEG 1010
G C G + ++ EY LG L ++L + + L++ +I E
Sbjct 653 LGACTYGG--PVLVITEYCSLGDLLNFLRQKAETFVNLVMNIPEIMEN 698
Score = 35.8 bits (81), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 24/86 (28%), Positives = 42/86 (49%), Gaps = 2/86 (2%)
Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSH-THLAFVHGV 676
GK+ + G D+ LRV +K+L +H D A ++S + H ++ + G
Sbjct 596 GKVVEATAFGLGEDKDNTLRVAVKMLKANAHSDEREALMSELKILSHLGHHQNIVNLLGA 655
Query 677 CVRGPENIMVTEYVEHGPLDVWLRRE 702
C G +++TEY G L +LR++
Sbjct 656 CTYGGPVLVITEYCSLGDLLNFLRQK 681
>sp|Q9PUF6|PGFRA_CHICK Platelet-derived growth factor receptor
alpha OS=Gallus gallus OX=9031 GN=PDGFRA PE=2 SV=1
Length=1087
Score = 109 bits (273), Expect = 7e-23, Method: Compositional matrix adjust.
Identities = 63/179 (35%), Positives = 94/179 (53%), Gaps = 16/179 (9%)
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ L LL F Q+ GM +L +++ +HRDLAARNVLL ++VKI DFGLA+ + Y
Sbjct 790 LSLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNY 849
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ PV W APE + + + SDVWS+G+ L+E+ + L GI
Sbjct 850 VS-KGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFS--------------LGGI 894
Query 1115 AQ-GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
G M ++ G R+ +PD EVY +M CW E RP+F +L I++++
Sbjct 895 LYPGMMVDSTFYNKIKSGYRMAKPDHATNEVYEIMVKCWNNEPEKRPSFYHLSEIVESL 953
Score = 52.0 bits (123), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 40/154 (26%), Positives = 68/154 (44%), Gaps = 22/154 (14%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L +KN VH ++ RN+LLA+ +K+ D G+ + V +
Sbjct 801 QVARGMEFLASKNCVHRDLAARNVLLAQ-------GKIVKICDFGLARDIMHDSNYVSKG 853
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + N +T D W +G L EI G FY +
Sbjct 854 STFLPVKWMAPESI--FDNLYTTLSDVWSYGILLWEIFSLGGILYPGMMVDST--FYNKI 909
Query 830 --QHRLPEP--SCPQLATLTSQCLTYEPTQRPSF 859
+R+ +P + ++ + +C EP +RPSF
Sbjct 910 KSGYRMAKPDHATNEVYEIMVKCWNNEPEKRPSF 943
>sp|P35918|VGFR2_MOUSE Vascular endothelial growth factor receptor
2 OS=Mus musculus OX=10090 GN=Kdr PE=1 SV=2
Length=1345
Score = 109 bits (272), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 70/197 (36%), Positives = 103/197 (52%), Gaps = 20/197 (10%)
Query 971 EKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029
EKSL V E L +D+L L L+ ++ Q+ +GM +L ++ IHRDLAARN+
Sbjct 978 EKSLSDVEEEEASEELYKDFLT-----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNI 1032
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
LL +VKI DFGLA+ + + +Y R + D P+ W APE + + + SDVWSFGV
Sbjct 1033 LLSEKNVVKICDFGLARDIYKDPDYVR-KGDARLPLKWMAPETIFDRVYTIQSDVWSFGV 1091
Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149
L+E+ + +S P K E L+ G R+ PD E+Y M
Sbjct 1092 LLWEIFS-LGASPYPGVKIDE------------EFCRRLKEGTRMRAPDYTTPEMYQTML 1138
Query 1150 NCWETEASFRPTFENLI 1166
+CW + + RP+F L+
Sbjct 1139 DCWHEDPNQRPSFSELV 1155
Score = 57.4 bits (137), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 50/199 (25%), Positives = 86/199 (43%), Gaps = 38/199 (19%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V +
Sbjct 1009 QVAKGMEFLASRKCIHRDLAARNILLSEKNV-------VKICDFGLARDIYKDPDYVRKG 1061
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--EHFYQ 828
+ W+APE + ++ + D W FG L EI G +P P K E F +
Sbjct 1062 DARLPLKWMAPETIFDRVYTIQS--DVWSFGVLLWEIFSLGASPY----PGVKIDEEFCR 1115
Query 829 R-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN---------- 873
R + R P+ + P++ C +P QRPSF ++ L L N
Sbjct 1116 RLKEGTRMRAPDYTTPEMYQTMLDCWHEDPNQRPSFSELVEHLGNLLQANAQQDGKDYIV 1175
Query 874 --LADVLTVNPDSPASDPT 890
+++ L++ DS S PT
Sbjct 1176 LPMSETLSMEEDSGLSLPT 1194
>sp|Q8VDG6|M3K21_MOUSE Mitogen-activated protein kinase kinase
kinase 21 OS=Mus musculus OX=10090 GN=Map3k21 PE=1 SV=2
Length=1002
Score = 108 bits (271), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 99/319 (31%), Positives = 148/319 (46%), Gaps = 60/319 (19%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW-----KQ 946
F + LK++ +G G FG+V + G+ VAVKA + D P+ + ++
Sbjct 107 FERLELKEL--IGAGGFGQVYRATWQ------GQEVAVKAARRD--PEQDAAAAAESVRR 156
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------------ 994
E + L H +II+ +G C Q L LV+E+ G+L L +
Sbjct 157 EARLFAMLRHPNIIQLRGVCLRQ--PHLCLVLEFARGGALNRALAAAASDPRAPGPRRAR 214
Query 995 -IGLAQLLLFAQQICEGMAYLHAQHYI---HRDLAARNVLL------DN--DRLVKIGDF 1042
I L+ +A QI GM YLH + + HRDL + N+LL D+ ++ +KI DF
Sbjct 215 RIPPQVLVNWAVQIARGMLYLHEEAVVPILHRDLKSSNILLLEKIEHDDICNKTLKITDF 274
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
GLA+ E H R+ G W APE ++ F SD+WS+GV L+ELLT
Sbjct 275 GLAR---EWHRTTRMSAAGT--YAWMAPEVIRSSLFSKGSDIWSYGVLLWELLTG----- 324
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
P + ++ + +A G + V +LT LP P CP LMK CWE + RP+F
Sbjct 325 EVPYRGIDGLAVAYG-VAVNKLT--------LPIPSTCPEPFAKLMKECWEQDPHIRPSF 375
Query 1163 ENLIPILKTVHEKYQGQAP 1181
++ L + E P
Sbjct 376 ALILQQLTAIEEAVLTNMP 394
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 73/272 (27%), Positives = 118/272 (43%), Gaps = 35/272 (13%)
Query 633 RGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
+GQE+ V DP A A A L + + H ++ + GVC+R P +V E+
Sbjct 130 QGQEVAVKAARRDPEQDAAAAAESVRREARLFAMLRHPNIIQLRGVCLRQPHLCLVLEFA 189
Query 691 EHGPLDVWLRRERGH-----------VPMAWKMVVAQQLASALSYLENKNLV---HGNVC 736
G L+ L +P + A Q+A + YL + +V H ++
Sbjct 190 RGGALNRALAAAASDPRAPGPRRARRIPPQVLVNWAVQIARGMLYLHEEAVVPILHRDLK 249
Query 737 GRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSRE-ERVERI------PWLAPECLPGGA 788
NILL ++ + + +K++D G L+RE R R+ W+APE + +
Sbjct 250 SSNILLLEKIEHDDICNKTLKITDFG-----LAREWHRTTRMSAAGTYAWMAPEVI--RS 302
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLT 845
+ S D W +G L E+ GE P + + + LP PS CP+ A L
Sbjct 303 SLFSKGSDIWSYGVLLWEL-LTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLM 361
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
+C +P RPSF IL+ LT ++ L ++
Sbjct 362 KECWEQDPHIRPSFALILQQLTAIEEAVLTNM 393
>sp|P79701|VGFR3_COTCO Vascular endothelial growth factor receptor
3 OS=Coturnix coturnix OX=9091 GN=FLT4 PE=2 SV=1
Length=1379
Score = 109 bits (272), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 61/182 (34%), Positives = 98/182 (54%), Gaps = 14/182 (8%)
Query 988 DYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
D L + + + L+ ++ Q+ GM +L ++ IHRDLAARN+LL + +VKI DFGLA+
Sbjct 1014 DDLWQSPLTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLSENNVVKICDFGLARD 1073
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ + +Y R + P+ W APE + + + SDVWSFGV L+E+ + +S P +
Sbjct 1074 IYKDPDYVR-KGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFS-LGASPYPGVQ 1131
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
E + + G R+ P+ E+Y +M +CW + RPTF +L+
Sbjct 1132 INE------------EFCQRFKDGTRMRAPEYTTAEIYRIMLSCWHGDPKERPTFSDLVE 1179
Query 1168 IL 1169
IL
Sbjct 1180 IL 1181
Score = 54.7 bits (130), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 48/193 (25%), Positives = 86/193 (45%), Gaps = 27/193 (14%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V +
Sbjct 1032 QVARGMEFLASRKCIHRDLAARNILLSENNV-------VKICDFGLARDIYKDPDYVRKG 1084
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + +T D W FG L EI G +P +E+ F QR
Sbjct 1085 SARLPLKWMAPESIFDKV--YTTQSDVWSFGVLLWEIFSLGASPYPGVQINEE--FCQRF 1140
Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL----ADVLTVN 881
+ R PE + ++ + C +P +RP+F ++ L L N+ D + +N
Sbjct 1141 KDGTRMRAPEYTTAEIYRIMLSCWHGDPKERPTFSDLVEILGNLLQENVQQEGKDYIPLN 1200
Query 882 PDSPASDPTVFHK 894
DS +S+ F +
Sbjct 1201 -DSHSSEDDGFSQ 1212
>sp|P20786|PGFRA_RAT Platelet-derived growth factor receptor alpha
OS=Rattus norvegicus OX=10116 GN=Pdgfra PE=1 SV=2
Length=1088
Score = 108 bits (271), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 65/181 (36%), Positives = 92/181 (51%), Gaps = 23/181 (13%)
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ L LL F Q+ GM +L +++ +HRDLAARNVLL ++VKI DFGLA+ + Y
Sbjct 789 LTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNY 848
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ PV W APE + + + SDVWS+GV L+E+ + L G
Sbjct 849 VS-KGSTFLPVKWMAPESIFDNLYTTLSDVWSYGVLLWEIFS--------------LGGT 893
Query 1115 AQ-GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF-------ENLI 1166
G M ++ G R+ +PD EVY +M CW +E RP+F ENL+
Sbjct 894 PYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLL 953
Query 1167 P 1167
P
Sbjct 954 P 954
Score = 58.2 bits (139), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 44/166 (27%), Positives = 73/166 (44%), Gaps = 22/166 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L +KN VH ++ RN+LLA+ +K+ D G+ + V +
Sbjct 800 QVARGMEFLASKNCVHRDLAARNVLLAQ-------GKIVKICDFGLARDIMHDSNYVSKG 852
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + N +T D W +G L EI G P FY +
Sbjct 853 STFLPVKWMAPESI--FDNLYTTLSDVWSYGVLLWEIFSLGGTPYPGMMVDST--FYNKI 908
Query 830 --QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
+R+ +P + ++ + QC EP +RPSF + + L P
Sbjct 909 KSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLP 954
>sp|Q9CAD5|YODA_ARATH Mitogen-activated protein kinase kinase
kinase YODA OS=Arabidopsis thaliana OX=3702 GN=YDA PE=1 SV=1
Length=883
Score = 108 bits (270), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 93/293 (32%), Positives = 137/293 (47%), Gaps = 33/293 (11%)
Query 882 PDSPA-SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQ 939
P SPA ++ TV KK R LG G FG V L N +GEM A+K + P+
Sbjct 384 PRSPARAEATVSPGSRWKKGRLLGMGSFGHVYLGF----NSESGEMCAMKEVTLCSDDPK 439
Query 940 HRSGWKQ---EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-I 995
R +Q EI +L L H++I++Y G + + L + +EYV GS+ L +
Sbjct 440 SRESAQQLGQEISVLSRLRHQNIVQYYG--SETVDDKLYIYLEYVSGGSIYKLLQEYGQF 497
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
G + + QQI G+AYLHA++ +HRD+ N+L+D VK+ DFG+AK +
Sbjct 498 GENAIRNYTQQILSGLAYLHAKNTVHRDIKGANILVDPHGRVKVADFGMAKHITAQSGPL 557
Query 1056 RVREDGDSPVFWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ SP +W APE +K A D+WS G T+ E+ T PP E
Sbjct 558 SFK---GSP-YWMAPEVIKNSNGSNLAVDIWSLGCTVLEMAT-----TKPPWSQYE---- 604
Query 1115 AQGQMTVLRLTELLERGERLPR-PDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
G + ++ E LP PD E ++ C + + RPT L+
Sbjct 605 --GVPAMFKIGNSKE----LPDIPDHLSEEGKDFVRKCLQRNPANRPTAAQLL 651
Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 49/173 (28%), Positives = 80/173 (46%), Gaps = 12/173 (7%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V L DP + A + S++S++ H ++ +G + + EYV G +
Sbjct 431 VTLCSDDPKSRESAQQLGQEISVLSRLRHQNIVQYYGSETVDDKLYIYLEYVSGGSI-YK 489
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
L +E G QQ+ S L+YL KN VH ++ G NIL+ G +K++
Sbjct 490 LLQEYGQFGENAIRNYTQQILSGLAYLHAKNTVHRDIKGANILVDPHGR-------VKVA 542
Query 759 DPGVG--LGALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
D G+ + A S + P W+APE + +N + A+D W G T+LE+
Sbjct 543 DFGMAKHITAQSGPLSFKGSPYWMAPEVI-KNSNGSNLAVDIWSLGCTVLEMA 594
>sp|P26618|PGFRA_MOUSE Platelet-derived growth factor receptor
alpha OS=Mus musculus OX=10090 GN=Pdgfra PE=1 SV=3
Length=1089
Score = 108 bits (270), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 63/180 (35%), Positives = 92/180 (51%), Gaps = 21/180 (12%)
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ L LL F Q+ GM +L +++ +HRDLAARNVLL ++VKI DFGLA+ + Y
Sbjct 790 LTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNY 849
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ PV W APE + + + SDVWS+G+ L+E+ + + P
Sbjct 850 VS-KGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFS-LGGTPYP---------- 897
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF-------ENLIP 1167
G M ++ G R+ +PD EVY +M CW +E RP+F ENL+P
Sbjct 898 --GMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLP 955
Score = 57.8 bits (138), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 44/166 (27%), Positives = 73/166 (44%), Gaps = 22/166 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L +KN VH ++ RN+LLA+ +K+ D G+ + V +
Sbjct 801 QVARGMEFLASKNCVHRDLAARNVLLAQ-------GKIVKICDFGLARDIMHDSNYVSKG 853
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + N +T D W +G L EI G P FY +
Sbjct 854 STFLPVKWMAPESI--FDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDST--FYNKI 909
Query 830 --QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
+R+ +P + ++ + QC EP +RPSF + + L P
Sbjct 910 KSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLP 955
>sp|P16234|PGFRA_HUMAN Platelet-derived growth factor receptor
alpha OS=Homo sapiens OX=9606 GN=PDGFRA PE=1 SV=1
Length=1089
Score = 108 bits (269), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 63/180 (35%), Positives = 92/180 (51%), Gaps = 21/180 (12%)
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ L LL F Q+ GM +L +++ +HRDLAARNVLL ++VKI DFGLA+ + Y
Sbjct 790 LTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNY 849
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ PV W APE + + + SDVWS+G+ L+E+ + + P
Sbjct 850 VS-KGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFS-LGGTPYP---------- 897
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF-------ENLIP 1167
G M ++ G R+ +PD EVY +M CW +E RP+F ENL+P
Sbjct 898 --GMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLP 955
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 43/166 (26%), Positives = 73/166 (44%), Gaps = 22/166 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L +KN VH ++ RN+LLA+ +K+ D G+ + V +
Sbjct 801 QVARGMEFLASKNCVHRDLAARNVLLAQ-------GKIVKICDFGLARDIMHDSNYVSKG 853
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + N +T D W +G L EI G P FY +
Sbjct 854 STFLPVKWMAPESI--FDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDST--FYNKI 909
Query 830 --QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
+R+ +P + ++ + +C EP +RPSF + + L P
Sbjct 910 KSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLP 955
>sp|Q39008|M3K1_ARATH Mitogen-activated protein kinase kinase
kinase 1 OS=Arabidopsis thaliana OX=3702 GN=MEKK1 PE=1 SV=2
Length=608
Score = 107 bits (266), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 83/272 (31%), Positives = 131/272 (48%), Gaps = 36/272 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQ---EIDILRTLYHEH 958
LG G FG V Y+ + G G+ AVK + D G Q + +Q EI +L L H++
Sbjct 339 LGRGSFGSV----YEGIS-GDGDFFAVKEVSLLDQGSQAQECIQQLEGEIKLLSQLQHQN 393
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I++Y+G +D +L + +E V GSL R+ + + + L+ +QI +G+ YLH +
Sbjct 394 IVRYRGTAKDG--SNLYIFLELVTQGSLLKLYQRYQLRDSVVSLYTRQILDGLKYLHDKG 451
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL--KEY 1076
+IHRD+ N+L+D + VK+ DFGLAK ++ ++ +P FW APE + K+
Sbjct 452 FIHRDIKCANILVDANGAVKLADFGLAKV----SKFNDIKSCKGTP-FWMAPEVINRKDS 506
Query 1077 KFYYA-SDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
Y + +D+WS G T+ E+ T S P + L IG RG
Sbjct 507 DGYGSPADIWSLGCTVLEMCTGQIPYSDLEPVQALFRIG----------------RGTLP 550
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
PD + + C + RPT L+
Sbjct 551 EVPDTLSLDARLFILKCLKVNPEERPTAAELL 582
Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 67/279 (24%), Positives = 114/279 (41%), Gaps = 45/279 (16%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LG+G+ +VYEG + G GD K V D+G + + ++ L+
Sbjct 339 LGRGSFGSVYEG---ISGDGDFFAVKE------VSLLDQGSQAQECIQQLEGE------- 382
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
L+SQ+ H ++ G G + E V G L +R + + +
Sbjct 383 ----IKLLSQLQHQNIVRYRGTAKDGSNLYIFLELVTQGSL--LKLYQRYQLRDSVVSLY 436
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+Q+ L YL +K +H ++ NIL+ G +KL+D GL +S+ ++
Sbjct 437 TRQILDGLKYLHDKGFIHRDIKCANILVDANGA-------VKLAD--FGLAKVSKFNDIK 487
Query 775 RIP----WLAPECLP-GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
W+APE + ++ + D W G T+LE+C G+ P P + R
Sbjct 488 SCKGTPFWMAPEVINRKDSDGYGSPADIWSLGCTVLEMC-TGQIPYSDLEPVQALF---R 543
Query 830 QHRLPEPSCPQLATLTS-----QCLTYEPTQRPSFRTIL 863
R P P +L + +CL P +RP+ +L
Sbjct 544 IGRGTLPEVPDTLSLDARLFILKCLKVNPEERPTAAELL 582
>sp|H2L099|GCK1_CAEEL Germinal center kinase 1 OS=Caenorhabditis
elegans OX=6239 GN=gck-1 PE=1 SV=1
Length=653
Score = 107 bits (266), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 70/207 (34%), Positives = 112/207 (54%), Gaps = 13/207 (6%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP V + K+ R +G G FG+V Y ++ TG +VA+K + + +QE
Sbjct 29 DPEVI---FTKQER-IGRGSFGEV----YKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQE 80
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +L +++ KY G +G K L ++MEY+ GS D + + + + ++I
Sbjct 81 IQVLSQCDSQYVTKYFGSFL-KGSK-LWIIMEYLGGGSALDLTKSGKLDESHIAVILREI 138
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+G+ YLH++ IHRD+ A NVL+ VK+ DFG+A + E + R+ G SP FW
Sbjct 139 LKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVK-KRITFVG-SP-FW 195
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYEL 1094
APE +K+ + Y +D+WS G+T EL
Sbjct 196 MAPELIKQSSYDYKADIWSLGITAIEL 222
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 57/241 (24%), Positives = 102/241 (42%), Gaps = 34/241 (14%)
Query 639 VVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LD 696
V +K++D D + ++SQ ++ G ++G + ++ EY+ G LD
Sbjct 60 VAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALD 119
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+ + G + + V+ +++ L YL ++ +H ++ N+L++ G +K
Sbjct 120 L---TKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHG-------DVK 169
Query 757 LSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
++D GV G L+ E +RI W+APE + +S D W G T +E+ +
Sbjct 170 VADFGVA-GQLT-ETVKKRITFVGSPFWMAPELIK--QSSYDYKADIWSLGITAIELA-N 224
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-------SCPQLATLTSQCLTYEPTQRPSFRTIL 863
GE P P + P P S P CL +P RPS T+L
Sbjct 225 GEPPHSDLHPMRVLFLIPKN---PPPVLQGSQWSKP-FKEFVEMCLNKDPENRPSASTLL 280
Query 864 R 864
+
Sbjct 281 K 281
>sp|E9Q3S4|M3K19_MOUSE Mitogen-activated protein kinase kinase
kinase 19 OS=Mus musculus OX=10090 GN=Map3k19 PE=3 SV=1
Length=1311
Score = 108 bits (269), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 72/234 (31%), Positives = 121/234 (52%), Gaps = 22/234 (9%)
Query 876 DVLTVNPDSPASDPTVFHKR--YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933
+ LT N SD ++ H+ + K LG G +G V YC + G+++AVK +
Sbjct 1021 NFLTSNEKKTLSDKSLNHEEAIFWTKGEILGRGAYGTV--YCGLTS---LGQLIAVKQVA 1075
Query 934 ADCG-----PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
D + ++E+D+L+ L H +I+ Y G C + E +L + ME+VP GS+
Sbjct 1076 LDTSDKLATEKEYRKLQEEVDLLKALKHVNIVAYLGTCLE--ENTLSIFMEFVPGGSISS 1133
Query 989 YLPRHSIGLAQLLL--FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
+ R L +++ + +QI +G+AYLH +HRD+ NV+L ++K+ DFG AK
Sbjct 1134 IINRFG-PLPEMVFCKYTRQILQGVAYLHDNCVVHRDIKGNNVMLMPTGIIKLIDFGCAK 1192
Query 1047 AVP----EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+ G ++ +P +W APE + E + SD+WS G T++E+ T
Sbjct 1193 RLAWAGLNGTHSDMLKSMRGTP-YWMAPEVINESGYGRKSDIWSIGCTVFEMAT 1245
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 55/225 (24%), Positives = 89/225 (40%), Gaps = 27/225 (12%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
E L+ + H ++ G C+ + E+V G + + R G +P
Sbjct 1091 LQEEVDLLKALKHVNIVAYLGTCLEENTLSIFMEFVPGGSISSIINR-FGPLPEMVFCKY 1149
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-------VGLGAL 767
+Q+ ++YL + +VH ++ G N++L G+ IKL D G GL
Sbjct 1150 TRQILQGVAYLHDNCVVHRDIKGNNVMLMPTGI-------IKLIDFGCAKRLAWAGLNGT 1202
Query 768 SRE--ERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ + + P W+APE + + D W G T+ E+ G+ PL S
Sbjct 1203 HSDMLKSMRGTPYWMAPEVI--NESGYGRKSDIWSIGCTVFEMAT-GKPPLASMD-RMAA 1258
Query 825 HFYQRQHRLPEPSCPQ-----LATLTSQCLTYEPTQRPSFRTILR 864
FY HR P P A CLT + +RPS +L+
Sbjct 1259 MFYIGAHRGLMPPLPARFSEPAADFVRLCLTRDQHERPSALQLLK 1303
>sp|A0A0K3AV08|MLK1_CAEEL Mitogen-activated protein kinase kinase
kinase mlk-1 OS=Caenorhabditis elegans OX=6239 GN=mlk-1
PE=1 SV=1
Length=1059
Score = 107 bits (268), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 81/275 (29%), Positives = 123/275 (45%), Gaps = 53/275 (19%)
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQL 1000
K+E +++ L H +I++ G C + + L++E SLR+ +I L L
Sbjct 217 KREANLVNGLSHNNIVRLLGICLE--DPYFGLLLELCEGSSLRNVCRNLNSDAAIPLGVL 274
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN------------------------DRL 1036
+ +A Q+ EGM YL Q Y+HRDL A NVL+ D+L
Sbjct 275 IDWATQVAEGMEYLTKQGYVHRDLKADNVLVKEEVCLCMDEEMFQYAYCLKCGKRPFDKL 334
Query 1037 -VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+KI DFG+ + + + W APE KE + ASDVWS+GV L+ELL
Sbjct 335 QLKITDFGVTRKMTADANRFSTA----GTYAWLAPEAFKEGTWSEASDVWSYGVVLWELL 390
Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155
T + P QG + ++ +G+ L D CP LM++CW E
Sbjct 391 TR----EEP----------YQGHIPATIAFQIANKGQNLSIGDSCPDRWKKLMQDCWNLE 436
Query 1156 ASFRPTFENLIPILKTVHEKYQG----QAPSVFSV 1186
+FRP F L K ++++ +APS +V
Sbjct 437 PNFRPKFSTLAISFKQYAKEFKDTHLQRAPSKMAV 471
Score = 57.4 bits (137), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 70/305 (23%), Positives = 120/305 (39%), Gaps = 49/305 (16%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
+G G V++ ++++ + + G+M G G +++ LK + +
Sbjct 155 QIGHGATATVFKMDIKIKK--ELQNGRM--------GEAVGDQMKAALKRFNRHASNFRA 204
Query 654 AFYET----------ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-- 701
T A+L++ +SH ++ + G+C+ P ++ E E L R
Sbjct 205 DVVSTDEQLEQLKREANLVNGLSHNNIVRLLGICLEDPYFGLLLELCEGSSLRNVCRNLN 264
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR---LGLAE--------- 749
+P+ + A Q+A + YL + VH ++ N+L+ L + E
Sbjct 265 SDAAIPLGVLIDWATQVAEGMEYLTKQGYVHRDLKADNVLVKEEVCLCMDEEMFQYAYCL 324
Query 750 --GTSPF----IKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGF 800
G PF +K++D GV + R WLAPE G + S A D W +
Sbjct 325 KCGKRPFDKLQLKITDFGVTRKMTADANRFSTAGTYAWLAPEAFKEG--TWSEASDVWSY 382
Query 801 GATLLEICFDGEAPLQSRSPSEK--EHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQRP 857
G L E+ E P Q P+ + + Q+ SCP + L C EP RP
Sbjct 383 GVVLWEL-LTREEPYQGHIPATIAFQIANKGQNLSIGDSCPDRWKKLMQDCWNLEPNFRP 441
Query 858 SFRTI 862
F T+
Sbjct 442 KFSTL 446
>sp|Q13546|RIPK1_HUMAN Receptor-interacting serine/threonine-protein
kinase 1 OS=Homo sapiens OX=9606 GN=RIPK1 PE=1 SV=3
Length=671
Score = 106 bits (265), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 88/275 (32%), Positives = 129/275 (47%), Gaps = 32/275 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+L G FGKVSL C+ T G M+ K +H +E ++ L H ++K
Sbjct 22 ELDSGGFGKVSL-CFHRTQ---GLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVK 77
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G ++G+ SL VMEY+ G+L L S L+ +I EGM YLH + I
Sbjct 78 LLGVIIEEGKYSL--VMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMCYLHGKGVI 135
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAK----AVPEGHEYYRVRE-DGDSP-----VFWYAP 1070
H+DL N+L+DND +KI D GLA + E+ +RE DG + +++ AP
Sbjct 136 HKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMAP 195
Query 1071 ECLKEY--KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM-TVLRLTEL 1127
E L + K SDV+SF V L+ + + + ++ + ++ I G V +TE
Sbjct 196 EHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEY 255
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
CP E+ LMK CWE RPTF
Sbjct 256 ------------CPREIISLMKLCWEANPEARPTF 278
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 52/232 (22%), Positives = 95/232 (41%), Gaps = 32/232 (14%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
A E A +M+++ H+ + + GV + + +V EY+E G L L+ E P++ K
Sbjct 59 ALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMS-TPLSVKGR 117
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGALSR 769
+ ++ + YL K ++H ++ NIL+ IK++D G+ L+
Sbjct 118 IILEIIEGMCYLHGKGVIHKDLKPENILV-------DNDFHIKIADLGLASFKMWSKLNN 170
Query 770 EERVE-------------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
EE E + ++APE L + D + F L I F + P +
Sbjct 171 EEHNELREVDGTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAI-FANKEPYE 229
Query 817 SRSPSEKEHFYQRQHRLPEPS-----CP-QLATLTSQCLTYEPTQRPSFRTI 862
+ ++ + P+ CP ++ +L C P RP+F I
Sbjct 230 NAICEQQLIMCIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGI 281
>sp|O64842|PBL12_ARATH Probable serine/threonine-protein kinase
PBL12 OS=Arabidopsis thaliana OX=3702 GN=PBL12 PE=2 SV=1
Length=424
Score = 104 bits (259), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 97/285 (34%), Positives = 136/285 (48%), Gaps = 21/285 (7%)
Query 903 LGEGHFGKV-SLYCYDPTNDGT-GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LGEG FG V + D G + VAVKAL HR W EI L L ++H++
Sbjct 94 LGEGGFGPVYKGFIDDKVKPGIEAQPVAVKALDLHGHQGHRE-WLAEILFLGQLSNKHLV 152
Query 961 KYKG-CCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLA--QLLLFAQQICEGMAYLHA 1016
K G CCE E+ LV EY+P GSL + L R+S+ +A + A +G+A+LH
Sbjct 153 KLIGFCCE---EEQRVLVYEYMPRGSLENQLFRRNSLAMAWGIRMKIALGAAKGLAFLHE 209
Query 1017 QH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG-HEYYRVREDGDSPVFWYAPECL 1073
I+RD N+LLD+D K+ DFGLAK PEG H + R G + APE +
Sbjct 210 AEKPVIYRDFKTSNILLDSDYNAKLSDFGLAKDGPEGEHTHVTTRVMGTQG--YAAPEYI 267
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER--G 1131
+DV+SFGV L EL+T S + T+ + + + +LR LER
Sbjct 268 MTGHLTTMNDVYSFGVVLLELITGKRSMDNTRTRREQ--SLVEWARPMLRDQRKLERIID 325
Query 1132 ERLPRPDKCPCE--VYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
RL K L C +RPT ++ +L+++ E
Sbjct 326 PRLANQHKTEAAQVAASLAYKCLSQHPKYRPTMCEVVKVLESIQE 370
Score = 60.8 bits (146), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 81/329 (25%), Positives = 135/329 (41%), Gaps = 56/329 (17%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+ + L L LS RV ++ + LG+G VY+G + +D + P
Sbjct 69 TSQKLRLFTLSELRVITHNFSRSNMLGEGGFGPVYKGFI---------------DDKVKP 113
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G + V +K LD H + + Q+S+ HL + G C + ++V EY
Sbjct 114 GIEAQP---VAVKALDLHGHQGHREWLAEILFLGQLSNKHLVKLIGFCCEEEQRVLVYEY 170
Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARL 745
+ G L+ L R R + MAW +M +A A L++L K +++ + NILL
Sbjct 171 MPRGSLENQLFR-RNSLAMAWGIRMKIALGAAKGLAFLHEAEKPVIYRDFKTSNILL--- 226
Query 746 GLAEGTSPFIKLSDPGVGLGALSREER--VERI----PWLAPECLPGGANSLSTAMDKWG 799
+ KLSD G+ E R+ + APE + G L+T D +
Sbjct 227 ----DSDYNAKLSDFGLAKDGPEGEHTHVTTRVMGTQGYAAPEYIMTG--HLTTMNDVYS 280
Query 800 FGATLLEICFDGEAPLQSRSPSEKEH------FYQRQHRLPEPSCPQL------------ 841
FG LLE+ + +R+ E+ + Q +L P+L
Sbjct 281 FGVVLLELITGKRSMDNTRTRREQSLVEWARPMLRDQRKLERIIDPRLANQHKTEAAQVA 340
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
A+L +CL+ P RP+ +++ L +Q
Sbjct 341 ASLAYKCLSQHPKYRPTMCEVVKVLESIQ 369
>sp|Q9LTC0|PBL19_ARATH Probable serine/threonine-protein kinase
PBL19 OS=Arabidopsis thaliana OX=3702 GN=PBL19 PE=1 SV=1
Length=410
Score = 104 bits (259), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 110/382 (29%), Positives = 172/382 (45%), Gaps = 38/382 (10%)
Query 815 LQSRSPSEKEHFYQRQHR----LPEPSCPQLA--TLTSQCLTYEPTQRPSFRTILRDLTR 868
+S+ P +++ + R L + S P+L + TS P PS R+I +DL
Sbjct 7 FKSKKPRKQQKDNNKNKRKGKELLQNSAPELTNRSETSSFNLQTPRSLPSPRSI-KDLYT 65
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE--- 925
+ NL V + S A+ VF ++ + +GEG FG V Y ++G
Sbjct 66 EREQNLR-VFSYEELSKAT--YVFSRKLV-----IGEGGFGIV--YKGKILSNGDSSDPP 115
Query 926 -MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ--LVMEYVP 982
+VA+K L G Q W E+ L + H +++K G C + GE ++ LV EY+
Sbjct 116 LVVAIKKLNRQ-GLQGHKQWLAEVQFLGVVNHPNVVKLIGYCSEDGETGIERLLVYEYMS 174
Query 983 LGSLRDYL-PR--HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
SL D+L PR H++ + L EG+ YLH I+RD + NVLLD+ K+
Sbjct 175 NRSLEDHLFPRRSHTLPWKKRLEIMLGAAEGLTYLHDLKVIYRDFKSSNVLLDDQFCPKL 234
Query 1040 GDFGLAKAVPEGHEYY----RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
DFGLA+ P+G + RV G + APE ++ SDV+SFGV LYE++
Sbjct 235 SDFGLAREGPDGDNTHVTTARVGTHG-----YAAPEYVQTGHLRLKSDVYSFGVVLYEII 289
Query 1096 T--HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
T P + L + + R + +++ R P + L C +
Sbjct 290 TGRRTIERNKPVAERRLLDWVKEYPADSQRFSMIVDPRLRNNYPAAGARSLAKLADLCLK 349
Query 1154 TEASFRPTFENLIPILKTVHEK 1175
RPT E ++ LK + E+
Sbjct 350 KNDKERPTMEIVVERLKKIIEE 371
>sp|P26619|PGFRA_XENLA Platelet-derived growth factor receptor
alpha OS=Xenopus laevis OX=8355 GN=pdgfra PE=2 SV=1
Length=1087
Score = 107 bits (267), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 65/195 (33%), Positives = 101/195 (52%), Gaps = 19/195 (10%)
Query 982 PLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
PL +++ L + + LL F Q+ GM +L +++ +HRDLAARNVLL + ++VK
Sbjct 774 PLSEVKNILSDDGFEGLTVLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAHGKIVK 833
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
I DFGLA+ + Y + PV W APE + + + SDVWSFG+ L+E+ +
Sbjct 834 ICDFGLARDIMHDSNYVS-KGSTFLPVKWMAPESIFDNLYTTLSDVWSFGILLWEIFS-- 890
Query 1099 DSSQSPPTKFLELIGIAQGQMTV-LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157
L G M V ++ G R+ +PD EVY +M CW +E
Sbjct 891 ------------LGGTPYPGMIVDSTFYNKIKSGYRMAKPDHATHEVYDIMVKCWNSEPE 938
Query 1158 FRPTFENLIPILKTV 1172
RP+F +L I++++
Sbjct 939 KRPSFRHLSDIVESL 953
Score = 58.2 bits (139), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 45/166 (27%), Positives = 73/166 (44%), Gaps = 22/166 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L +KN VH ++ RN+LLA +K+ D G+ + V +
Sbjct 801 QVARGMEFLASKNCVHRDLAARNVLLAH-------GKIVKICDFGLARDIMHDSNYVSKG 853
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + N +T D W FG L EI G P FY +
Sbjct 854 STFLPVKWMAPESI--FDNLYTTLSDVWSFGILLWEIFSLGGTPYPGMIVDST--FYNKI 909
Query 830 --QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
+R+ +P + ++ + +C EP +RPSFR + + L P
Sbjct 910 KSGYRMAKPDHATHEVYDIMVKCWNSEPEKRPSFRHLSDIVESLLP 955
>sp|P36888|FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3
OS=Homo sapiens OX=9606 GN=FLT3 PE=1 SV=2
Length=993
Score = 107 bits (267), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 64/194 (33%), Positives = 101/194 (52%), Gaps = 18/194 (9%)
Query 978 MEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037
+EY L + + + LL FA Q+ +GM +L + +HRDLAARNVL+ + ++V
Sbjct 766 IEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVV 825
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
KI DFGLA+ + Y VR + PV W APE L E + SDVWS+G+ L+E+ +
Sbjct 826 KICDFGLARDIMSDSNYV-VRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFS- 883
Query 1098 CDSSQSPPTKFLELIGIA--QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155
+G+ G +L++ G ++ +P E+Y +M++CW +
Sbjct 884 --------------LGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFD 929
Query 1156 ASFRPTFENLIPIL 1169
+ RP+F NL L
Sbjct 930 SRKRPSFPNLTSFL 943
Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 54/209 (26%), Positives = 91/209 (44%), Gaps = 31/209 (15%)
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771
+ A Q+A + +LE K+ VH ++ RN+L+ +K+ D G+ +S
Sbjct 789 LCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTH-------GKVVKICDFGLARDIMSDSN 841
Query 772 RVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
V R + W+APE L G ++ + D W +G L EI G P P + +
Sbjct 842 YVVRGNARLPVKWMAPESLFEGIYTIKS--DVWSYGILLWEIFSLGVNPYPG-IPVDA-N 897
Query 826 FY---QRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD---V 877
FY Q ++ +P + ++ + C ++ +RPSF +LT LAD
Sbjct 898 FYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSF----PNLTSFLGCQLADAEEA 953
Query 878 LTVNPDSPASDP--TVFHKRYLKKIRDLG 904
+ N D S+ T ++R + DLG
Sbjct 954 MYQNVDGRVSECPHTYQNRRPFSREMDLG 982
>sp|Q5TCX8|M3K21_HUMAN Mitogen-activated protein kinase kinase
kinase 21 OS=Homo sapiens OX=9606 GN=MAP3K21 PE=1 SV=3
Length=1036
Score = 107 bits (267), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 96/328 (29%), Positives = 151/328 (46%), Gaps = 74/328 (23%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW-----K 945
F + LK++ +G G FG+V + G+ VAVKA + D P+ + +
Sbjct 120 AFERLELKEL--IGAGGFGQVYRATWQ------GQEVAVKAARQD--PEQDAAAAAESVR 169
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY---------------- 989
+E + L H +II+ +G C Q L LV+E+ G+L
Sbjct 170 REARLFAMLRHPNIIELRGVCLQQPH--LCLVLEFARGGALNRALAAANAAPDPRAPGPR 227
Query 990 ----LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI---HRDLAARNVLL------DN--D 1034
+P H L+ +A QI GM YLH + ++ HRDL + N+LL D+ +
Sbjct 228 RARRIPPHV-----LVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICN 282
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-WYAPECLKEYKFYYASDVWSFGVTLYE 1093
+ +KI DFGLA+ E++R + + + W APE +K F SD+WS+GV L+E
Sbjct 283 KTLKITDFGLAR------EWHRTTKMSTAGTYAWMAPEVIKSSLFSKGSDIWSYGVLLWE 336
Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
LLT P + ++ + +A G + V +LT LP P CP LMK CW+
Sbjct 337 LLTG-----EVPYRGIDGLAVAYG-VAVNKLT--------LPIPSTCPEPFAKLMKECWQ 382
Query 1154 TEASFRPTFENLIPILKTVHEKYQGQAP 1181
+ RP+F ++ L + + P
Sbjct 383 QDPHIRPSFALILEQLTAIEGAVMTEMP 410
Score = 53.9 bits (128), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 68/279 (24%), Positives = 104/279 (37%), Gaps = 61/279 (22%)
Query 633 RGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
+GQE+ V DP A A A L + + H ++ + GVC++ P +V E+
Sbjct 144 QGQEVAVKAARQDPEQDAAAAAESVRREARLFAMLRHPNIIELRGVCLQQPHLCLVLEFA 203
Query 691 EHGPLDVWLRRERG-----------------HVPMAWKMVVAQQLASALSYLENKNLV-- 731
G L+ L HV + W A Q+A + YL + V
Sbjct 204 RGGALNRALAAANAAPDPRAPGPRRARRIPPHVLVNW----AVQIARGMLYLHEEAFVPI 259
Query 732 -----------------HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
H ++C + + + GLA K+S G
Sbjct 260 LHRDLKSSNILLLEKIEHDDICNKTLKITDFGLAREWHRTTKMSTAGT------------ 307
Query 775 RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRL 833
W+APE + ++ S D W +G L E+ GE P + + + L
Sbjct 308 -YAWMAPEVI--KSSLFSKGSDIWSYGVLLWEL-LTGEVPYRGIDGLAVAYGVAVNKLTL 363
Query 834 PEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P PS CP+ A L +C +P RPSF IL LT ++
Sbjct 364 PIPSTCPEPFAKLMKECWQQDPHIRPSFALILEQLTAIE 402
>sp|Q9LFP7|PBL34_ARATH Serine/threonine-protein kinase PBL34 OS=Arabidopsis
thaliana OX=3702 GN=PBL34 PE=1 SV=1
Length=493
Score = 105 bits (261), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 94/286 (33%), Positives = 134/286 (47%), Gaps = 28/286 (10%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LGEG FG V + P GTG VAVK L D G Q W EI+ L L H
Sbjct 148 LGEGGFGCVFKGWIEENGTAPVKPGTGLTVAVKTLNPD-GLQGHKEWLAEINFLGNLLHP 206
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLH 1015
+++K G C + ++ LV E++P GSL ++L R S+ L + + A +G+++LH
Sbjct 207 NLVKLVGYCIEDDQR--LLVYEFMPRGSLENHLFRRSLPLPWSIRMKIALGAAKGLSFLH 264
Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPE 1071
+ I+RD N+LLD D K+ DFGLAK P EG + R G + APE
Sbjct 265 EEALKPVIYRDFKTSNILLDADYNAKLSDFGLAKDAPDEGKTHVSTRVMGT--YGYAAPE 322
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQ-MTVLRLTELLE 1129
+ SDV+SFGV L E+LT S ++ P L+ A+ + R LL+
Sbjct 323 YVMTGHLTSKSDVYSFGVVLLEMLTGRRSMDKNRPNGEHNLVEWARPHLLDKRRFYRLLD 382
Query 1130 RGERLPRPD-----KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
PR + K +V L C + RP +++ LK
Sbjct 383 -----PRLEGHFSIKGAQKVTQLAAQCLSRDPKIRPKMSDVVEALK 423
Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 85/360 (24%), Positives = 146/360 (41%), Gaps = 67/360 (19%)
Query 554 QP-GETSNLIIMRGARASPRT------LNLS----QLSFH--RVDQKEITQLSHLGQGTR 600
QP G+ S+ A +S T LN+S + +F+ ++ + S LG+G
Sbjct 94 QPVGQVSSTTTTSNAESSSSTPVISEELNISSHLRKFTFNDLKLSTRNFRPESLLGEGGF 153
Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660
V++G + G+ P+ PG L V +K L+P + +
Sbjct 154 GCVFKGWIEENGTA-----------PVKPGTG----LTVAVKTLNPDGLQGHKEWLAEIN 198
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
+ + H +L + G C+ + ++V E++ G L+ L R +P + +M +A A
Sbjct 199 FLGNLLHPNLVKLVGYCIEDDQRLLVYEFMPRGSLENHLFRRSLPLPWSIRMKIALGAAK 258
Query 721 ALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-----GALSREER 772
LS+L K +++ + NILL A KLSD G+ G R
Sbjct 259 GLSFLHEEALKPVIYRDFKTSNILLDADYNA-------KLSDFGLAKDAPDEGKTHVSTR 311
Query 773 V-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ--- 828
V + APE + G L++ D + FG LLE+ G + P+ + + +
Sbjct 312 VMGTYGYAAPEYVMTG--HLTSKSDVYSFGVVLLEM-LTGRRSMDKNRPNGEHNLVEWAR 368
Query 829 -------RQHRLPEP---------SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
R +RL +P ++ L +QCL+ +P RP ++ L L PH
Sbjct 369 PHLLDKRRFYRLLDPRLEGHFSIKGAQKVTQLAAQCLSRDPKIRPKMSDVVEALKPL-PH 427
>sp|A2QHV0|SEPH_ASPNC Cytokinesis protein sepH OS=Aspergillus
niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) OX=425011
GN=sepH PE=3 SV=1
Length=1336
Score = 107 bits (267), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 72/200 (36%), Positives = 101/200 (51%), Gaps = 23/200 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG+G FG V Y N TGE VAVK +K D EID+L+ L H +I+K
Sbjct 65 LGKGAFGSV----YRALNWNTGETVAVKQIKLVDLPKSELRVIMLEIDLLKNLDHPNIVK 120
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY------LPRHSIGLAQLLLFAQQICEGMAYLH 1015
Y+G + ++L +++EY GSL P + +GL + Q+ G+ YLH
Sbjct 121 YQGFV--KSAETLNIILEYCENGSLHSIAKNFGRFPENLVGL-----YMSQVLHGLLYLH 173
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
Q IHRD+ N+L + LVK+ DFG+A E V +P +W APE ++
Sbjct 174 EQGVIHRDIKGANILTTKEGLVKLADFGVASRTTGLSESSVV----GTP-YWMAPEVIEL 228
Query 1076 YKFYYASDVWSFGVTLYELL 1095
ASD+WS G T+ ELL
Sbjct 229 SGATTASDIWSLGCTVIELL 248
Score = 63.9 bits (154), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 59/229 (26%), Positives = 99/229 (43%), Gaps = 18/229 (8%)
Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
+K++D ++ + E L+ + H ++ G ++ EY E+G L +
Sbjct 90 IKLVDLPKSELRVIMLEI-DLLKNLDHPNIVKYQGFVKSAETLNIILEYCENGSLHS-IA 147
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G P + Q+ L YL + ++H ++ G NIL + GL +KL+D
Sbjct 148 KNFGRFPENLVGLYMSQVLHGLLYLHEQGVIHRDIKGANILTTKEGL-------VKLADF 200
Query 761 GVG--LGALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
GV LS V W+APE + GA +TA D W G T++E+ +G+ P +
Sbjct 201 GVASRTTGLSESSVVGTPYWMAPEVIELSGA---TTASDIWSLGCTVIEL-LEGKPPYYN 256
Query 818 RSPSEKE-HFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
P H LP+ + P + QC +P R S R +L+
Sbjct 257 LQPMPALFRIVNDDHPPLPQGASPAVKDFLMQCFQKDPNLRVSARKLLK 305
>sp|Q54RR9|Y9844_DICDI Probable serine/threonine-protein kinase
DDB_G0282963 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0282963
PE=3 SV=1
Length=1761
Score = 107 bits (267), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 75/287 (26%), Positives = 143/287 (50%), Gaps = 32/287 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I+ +G G F KV Y GE+VA+K LK + + +K+E DIL + +++
Sbjct 1479 IKKIGAGSFSKVYKAKY------MGEIVAIKVLKGEATSEQIELFKKEYDILSLVSSQNL 1532
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYLHAQ 1017
IK+ G C+ EK L++V EY GSL + + + ++ L+F Q +G+ LH
Sbjct 1533 IKFYGACK---EKKLRMVTEYCQHGSLYHIMSKRKMDISWPLVFKWMHQAVDGINSLHTM 1589
Query 1018 H--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV----FWYAPE 1071
+HRD+ ++N+L+++ +K+ DFGLAK ++ +S + + APE
Sbjct 1590 RPALVHRDIKSQNLLINSQFDLKVADFGLAKPT-------ELQTGSNSTIKGTMAYCAPE 1642
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLTELLE 1129
+ +DV+S G+ L+E+ T + Q P E+ Q+ ++ +
Sbjct 1643 LYNGISYSEKADVYSLGIVLWEITTRVITGKYQRPYEDNTEI--SFDFQIVIMS----SK 1696
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
+G R P P ++ +L++ CW + + RP+ + ++ + ++++ Y
Sbjct 1697 QGIRPTMPPNVPPKLSYLIQKCWNQDPNERPSCQQILLAITSLYDDY 1743
Score = 43.1 bits (100), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 64/254 (25%), Positives = 108/254 (43%), Gaps = 37/254 (15%)
Query 639 VVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +KVL + + I L F + ++S VS +L +G C + + MVTEY +HG L
Sbjct 1500 VAIKVLKGEATSEQIEL-FKKEYDILSLVSSQNLIKFYGAC-KEKKLRMVTEYCQHGSLY 1557
Query 697 VWLRRERGHVPMAWKMVVA--QQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTS 752
+ + + + ++W +V Q ++ L LVH ++ +N+L+ S
Sbjct 1558 HIMSKRK--MDISWPLVFKWMHQAVDGINSLHTMRPALVHRDIKSQNLLI--------NS 1607
Query 753 PF-IKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
F +K++D G+ L S + + APE G S S D + G L EI
Sbjct 1608 QFDLKVADFGLAKPTELQTGSNSTIKGTMAYCAPELYNGI--SYSEKADVYSLGIVLWEI 1665
Query 808 C---FDGEAPLQSRSPSEKEHFYQR---------QHRLPEPSCPQLATLTSQCLTYEPTQ 855
G+ +E +Q + +P P+L+ L +C +P +
Sbjct 1666 TTRVITGKYQRPYEDNTEISFDFQIVIMSSKQGIRPTMPPNVPPKLSYLIQKCWNQDPNE 1725
Query 856 RPSFRTILRDLTRL 869
RPS + IL +T L
Sbjct 1726 RPSCQQILLAITSL 1739
>sp|Q8AXC7|PGFRA_TAKRU Platelet-derived growth factor receptor
alpha OS=Takifugu rubripes OX=31033 GN=pdgfra PE=3 SV=1
Length=1062
Score = 106 bits (265), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 65/203 (32%), Positives = 100/203 (49%), Gaps = 29/203 (14%)
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
LL F Q+ +GM +L +++ +HRDLAARNVLL ++VKI DFGLA+ + + Y +
Sbjct 769 DLLSFTYQVAKGMEFLASKNCVHRDLAARNVLLSQGKIVKICDFGLARDIMHDNNYVS-K 827
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
PV W APE + + + SDVWS+G+ L+E+ + L G
Sbjct 828 GSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFS--------------LGGTPYPG 873
Query 1119 MTV-LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV----- 1172
M V ++ G R+ +P+ P +VY +M CW +E RP+F L + ++
Sbjct 874 MIVDSSFYNKIKSGYRMSKPEHAPQDVYDMMMKCWNSEPEKRPSFLGLSDTIASLLPSSY 933
Query 1173 --------HEKYQGQAPSVFSVC 1187
HE + P+V VC
Sbjct 934 KRHYERVNHEFLKSDHPAVTRVC 956
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 44/166 (27%), Positives = 73/166 (44%), Gaps = 22/166 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L +KN VH ++ RN+LL++ +K+ D G+ + V +
Sbjct 776 QVAKGMEFLASKNCVHRDLAARNVLLSQ-------GKIVKICDFGLARDIMHDNNYVSKG 828
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + N +T D W +G L EI G P FY +
Sbjct 829 STFLPVKWMAPESI--FDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMIVDSS--FYNKI 884
Query 830 --QHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
+R+ +P PQ + + +C EP +RPSF + + L P
Sbjct 885 KSGYRMSKPEHAPQDVYDMMMKCWNSEPEKRPSFLGLSDTIASLLP 930
>sp|Q8VYG0|LRL13_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE
PROTEIN KINASE-like 1.3 OS=Arabidopsis thaliana
OX=3702 GN=LRK10L-1.3 PE=2 SV=1
Length=686
Score = 105 bits (263), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 102/364 (28%), Positives = 164/364 (45%), Gaps = 28/364 (8%)
Query 826 FYQRQHRLP-EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884
F +R+ +L + + L+T T Y + P+ TI L P + + S
Sbjct 285 FIRRRKKLATQYTNKGLSTTTPYSSNYTMSNTPTSTTISGSNHSLVP----SISNLGNGS 340
Query 885 PASDPTVFHKRYLKKI-----RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
S VF L++ ++LG+G FG V Y DG VAVK L + +
Sbjct 341 VYSGIQVFSYEELEEATENFSKELGDGGFGTVY---YGTLKDG--RAVAVKRL-FERSLK 394
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----- 994
+K EIDIL++L H +++ GC + + L LV EY+ G+L ++L +
Sbjct 395 RVEQFKNEIDILKSLKHPNLVILYGC-TTRHSRELLLVYEYISNGTLAEHLHGNQAQSRP 453
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
I L A + ++YLHA IHRD+ N+LLD++ VK+ DFGL++ P +
Sbjct 454 ICWPARLQIAIETASALSYLHASGIIHRDVKTTNILLDSNYQVKVADFGLSRLFPMDQTH 513
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLEL 1111
G + PE + Y+ SDV+SFGV L EL++ D ++ L
Sbjct 514 ISTAPQGTPG--YVDPEYYQCYRLNEKSDVYSFGVVLSELISSKEAVDITRHRHDINLAN 571
Query 1112 IGIAQGQM-TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ I++ Q V L +L R P K V L C + E RP+ + ++ +L+
Sbjct 572 MAISKIQNDAVHELADLSLGFARDPSVKKMMSSVAELAFRCLQQERDVRPSMDEIVEVLR 631
Query 1171 TVHE 1174
+ +
Sbjct 632 VIQK 635
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 64/256 (25%), Positives = 109/256 (43%), Gaps = 48/256 (19%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDVWLRRERGHV-PMAW-- 710
F ++ + H +L ++G R E ++V EY+ +G L L + P+ W
Sbjct 399 FKNEIDILKSLKHPNLVILYGCTTRHSRELLLVYEYISNGTLAEHLHGNQAQSRPICWPA 458
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
++ +A + ASALSYL ++H +V NILL ++ +K++D G LSR
Sbjct 459 RLQIAIETASALSYLHASGIIHRDVKTTNILL-------DSNYQVKVADFG-----LSRL 506
Query 771 ERVERIPW-LAPECLPGGAN-------SLSTAMDKWGFGATLLEICFDGEA--------- 813
+++ AP+ PG + L+ D + FG L E+ EA
Sbjct 507 FPMDQTHISTAPQGTPGYVDPEYYQCYRLNEKSDVYSFGVVLSELISSKEAVDITRHRHD 566
Query 814 -PLQSRSPSEKEHFYQRQHRLP--------EPSCPQL----ATLTSQCLTYEPTQRPSFR 860
L + + S+ ++ H L +PS ++ A L +CL E RPS
Sbjct 567 INLANMAISKIQN--DAVHELADLSLGFARDPSVKKMMSSVAELAFRCLQQERDVRPSMD 624
Query 861 TILRDLTRLQPHNLAD 876
I+ L +Q ++D
Sbjct 625 EIVEVLRVIQKDGISD 640
>sp|Q5GIT4|VGFR2_DANRE Vascular endothelial growth factor receptor
2 OS=Danio rerio OX=7955 GN=kdr PE=1 SV=2
Length=1357
Score = 107 bits (266), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 63/172 (37%), Positives = 94/172 (55%), Gaps = 14/172 (8%)
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ + L+ ++ Q+ +GM +L ++ IHRDLAARN+LL + +VKI DFGLA+ V + +Y
Sbjct 1011 LTMEDLISYSFQVAKGMEFLASRKCIHRDLAARNILLSENSVVKICDFGLARDVYKDPDY 1070
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
R + D P+ W APE + + + SDVWSFGV L+E+ + +S P G+
Sbjct 1071 VR-KGDARLPLKWMAPETIFDRVYTTQSDVWSFGVLLWEIFS-LGASPYP--------GV 1120
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ RL E G R+ PD E+Y M +CW RPTF L+
Sbjct 1121 CIDESFCRRLKE----GTRMRAPDYATPEIYQTMLDCWLDRPLDRPTFTQLV 1168
Score = 52.4 bits (124), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 62/257 (24%), Positives = 98/257 (38%), Gaps = 47/257 (18%)
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG--VCVRGPEN 683
P +P R R V + DP D+ L + T L G VC R E
Sbjct 952 PRMPNR------REVQQDEDPREGDLGLG-----------TSTRLDICTGTAVCTRTGEQ 994
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
T E D W H+ M + + Q+A + +L ++ +H ++ RNILL+
Sbjct 995 TYKTLQDEQESSD-W-----DHLTMEDLISYSFQVAKGMEFLASRKCIHRDLAARNILLS 1048
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDK 797
+ +K+ D G+ + V + + W+APE + +T D
Sbjct 1049 E-------NSVVKICDFGLARDVYKDPDYVRKGDARLPLKWMAPETIFDRV--YTTQSDV 1099
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-----QHRLPEPSCPQLATLTSQCLTYE 852
W FG L EI G +P E F +R + R P+ + P++ C
Sbjct 1100 WSFGVLLWEIFSLGASPYPGVCIDES--FCRRLKEGTRMRAPDYATPEIYQTMLDCWLDR 1157
Query 853 PTQRPSFRTILRDLTRL 869
P RP+F ++ L L
Sbjct 1158 PLDRPTFTQLVEHLGNL 1174
>sp|Q8IR79|LIMK1_DROME LIM domain kinase 1 OS=Drosophila melanogaster
OX=7227 GN=LIMK1 PE=1 SV=1
Length=1257
Score = 106 bits (265), Expect = 8e-22, Method: Compositional matrix adjust.
Identities = 74/228 (32%), Positives = 117/228 (51%), Gaps = 43/228 (19%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG FGKV + T+ +GE++ +K L +AD + + + +E+ +LR L H H++K
Sbjct 407 LGEGFFGKV----FKVTHRQSGEVMVLKELHRAD--EEAQRNFIKEVAVLRLLDHRHVLK 460
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G +K L +V EYV G L++ + P + Q + A+ I GM+YLH+ +
Sbjct 461 FIGVL--YKDKKLHMVTEYVAGGCLKELIHDPAQVLPWPQRVRLARDIACGMSYLHSMNI 518
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAV-----PEGHEY---YRVREDGDSPV------ 1065
IHRDL + N L+ DR V + DFGLA++V P G+ Y + D+P+
Sbjct 519 IHRDLNSMNCLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTL 578
Query 1066 ------------------FWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+W APE +K K+ DV+SFG+ L E++
Sbjct 579 RRSKSRQRRQRYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEII 626
Score = 54.7 bits (130), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 67/276 (24%), Positives = 108/276 (39%), Gaps = 44/276 (16%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+VLK L + + F + +++ + H H+ GV + + MVTEYV G L
Sbjct 427 MVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKEL 486
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG--------RNILLARLGLAEG 750
+ +P ++ +A+ +A +SYL + N++H ++ R++++A GLA
Sbjct 487 IHDPAQVLPWPQRVRLARDIACGMSYLHSMNIIHRDLNSMNCLVREDRSVIVADFGLARS 546
Query 751 TS----PFIKLSDPGVGLGALSREER--------------------VERIPWLAPECLPG 786
P ++ G G GA S V W+APE + G
Sbjct 547 VDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKG 606
Query 787 GANSLSTAMDKWGFGATLLEICFDGEA-----PLQSRSPSEKEHFYQR-QHRLPEPSCPQ 840
+D + FG L EI EA P S ++ F ++ + PEP
Sbjct 607 L--KYDEKVDVFSFGIMLCEIIGRVEADPDFMPRNSDFSLNQQEFREKFCAQCPEP---- 660
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
+ C P RP F T+ L RL AD
Sbjct 661 FVKVAFVCCDLNPDMRPCFETLHVWLQRLADDLAAD 696
>sp|O14047|PPK11_SCHPO Serine/threonine-protein kinase ppk11 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=ppk11 PE=3 SV=1
Length=312
Score = 101 bits (251), Expect = 8e-22, Method: Compositional matrix adjust.
Identities = 66/209 (32%), Positives = 101/209 (48%), Gaps = 16/209 (8%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
K + ++ +G+G FG V + + + ++VA+K + D QEI+ L
Sbjct 1 MEKHQYRDLQLIGQGSFGSV----FRAQDVESSKIVALKVVDLDATKDQIETLTQEINFL 56
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEG 1010
L HI KY D L + MEY GS D L +++ +Q+ E
Sbjct 57 IDLNSVHITKYYASFVDGFR--LWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEA 114
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---FW 1067
+ YLH Q +HRD+ A N+L D LVK+ DFG++ + +R+ D V FW
Sbjct 115 LVYLHGQGKMHRDIKAANILTMKDGLVKLADFGVSGQLES------LRDKNDDFVGTPFW 168
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096
APE +K+ + Y +D+WS G+T YEL T
Sbjct 169 MAPEVVKQTGYNYKADIWSLGITAYELAT 197
Score = 40.4 bits (93), Expect = 0.080, Method: Compositional matrix adjust.
Identities = 56/235 (24%), Positives = 88/235 (37%), Gaps = 33/235 (14%)
Query 639 VVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LD 696
V LKV+D + D + + + ++ H+ + V G + EY + G LD
Sbjct 32 VALKVVDLDATKDQIETLTQEINFLIDLNSVHITKYYASFVDGFRLWITMEYCDGGSCLD 91
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
L + G V +Q+ AL YL + +H ++ NIL + GL +K
Sbjct 92 --LLKLSGTFSERVIAEVMRQVLEALVYLHGQGKMHRDIKAANILTMKDGL-------VK 142
Query 757 LSDPGVGLGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
L+D GV S ++ + W+APE + + D W G T E+ GE
Sbjct 143 LADFGVSGQLESLRDKNDDFVGTPFWMAPEVVK--QTGYNYKADIWSLGITAYELA-TGE 199
Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQL---------ATLTSQCLTYEPTQRPS 858
P P + +P+ S P L S CL P R +
Sbjct 200 PPYSGIHPMKVLLL------IPKHSPPSLERSKFSRAFCDFVSNCLKKNPKDRAT 248
>sp|Q8QHL3|VGFR1_CHICK Vascular endothelial growth factor receptor
1 OS=Gallus gallus OX=9031 GN=FLT1 PE=2 SV=1
Length=1327
Score = 106 bits (264), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 57/172 (33%), Positives = 94/172 (55%), Gaps = 14/172 (8%)
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ + L+ ++ Q+ GM +L ++ IHRDLAARN+LL + +VKI DFGLA+ + + +Y
Sbjct 987 LTMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDY 1046
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
R + D P+ W APE + + + SDVWS+GV L+E+ + +S P + E
Sbjct 1047 VR-KGDARLPLKWMAPESIFDKIYNTKSDVWSYGVLLWEIFS-LGASPYPGVQIDE---- 1100
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L+ G R+ P++ E+Y +M +CW + + RP F L+
Sbjct 1101 --------DFCSKLKEGTRMRAPEQATEEIYQIMLDCWRSNPNERPWFSELV 1144
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 22/164 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V +
Sbjct 998 QVARGMEFLSSRKCIHRDLAARNILLSE-------NNVVKICDFGLARDIYKNPDYVRKG 1050
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + +T D W +G L EI G +P E F +
Sbjct 1051 DARLPLKWMAPESIFDKI--YNTKSDVWSYGVLLWEIFSLGASPYPGVQID--EDFCSKL 1106
Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ R PE + ++ + C P +RP F +++ L L
Sbjct 1107 KEGTRMRAPEQATEEIYQIMLDCWRSNPNERPWFSELVKRLGDL 1150
>sp|Q54RZ7|Y1199_DICDI Probable serine/threonine-protein kinase
DDB_G0282895 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0282895
PE=3 SV=1
Length=1634
Score = 106 bits (264), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 74/273 (27%), Positives = 131/273 (48%), Gaps = 26/273 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ ++ LGEG +V + G+ VAVK + +E+ IL + H
Sbjct 1377 LQILQFLGEGALAEVHKGIWK------GKEVAVKIFNEGSFSFRLEDFLKEVAILGLISH 1430
Query 957 EHIIKYKGCC--EDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAY 1013
+++K KG C + + +V E + G+L + + ++ + L ++ +A + +G+AY
Sbjct 1431 PNLLKLKGACIAPRSHKSTFMIVTELMHKGTLLEVINKNKPLSLEDIIKYALSVAQGLAY 1490
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
LH+ +IHRD+ A N+L+D + K+GDFGL++ + V +P W +PECL
Sbjct 1491 LHSVDFIHRDIKAANILVDKNNNAKVGDFGLSRVIDNNFNMTAV---AGTPK-WESPECL 1546
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ ASDV+S+G+ L+EL T + FLE+ I + +V ++ +
Sbjct 1547 MGEAYTSASDVYSYGMMLFELATGDE-------PFLEIQSIVELARSV------CDKKLK 1593
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
P + L+K+C RPT +I
Sbjct 1594 PKISSSVPNFISSLIKDCLHNSPKKRPTMNQII 1626
Score = 61.6 bits (148), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 58/246 (24%), Positives = 116/246 (47%), Gaps = 25/246 (10%)
Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPEN-----IMV 686
+G+E V +K+ + L F + +++ +SH +L + G C+ P + ++V
Sbjct 1397 KGKE--VAVKIFNEGSFSFRLEDFLKEVAILGLISHPNLLKLKGACI-APRSHKSTFMIV 1453
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLAR 744
TE + G L + + + P++ + ++ A +A L+YL + + +H ++ NIL+ +
Sbjct 1454 TELMHKGTLLEVINKNK---PLSLEDIIKYALSVAQGLAYLHSVDFIHRDIKAANILVDK 1510
Query 745 LGLAE-GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
A+ G ++ D + A++ + W +PECL G A ++A D + +G
Sbjct 1511 NNNAKVGDFGLSRVIDNNFNMTAVAGTPK-----WESPECLMGEA--YTSASDVYSYGMM 1563
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE--PSCPQ-LATLTSQCLTYEPTQRPSFR 860
L E+ E L+ +S E + P+ S P +++L CL P +RP+
Sbjct 1564 LFELATGDEPFLEIQSIVELARSVCDKKLKPKISSSVPNFISSLIKDCLHNSPKKRPTMN 1623
Query 861 TILRDL 866
I++ L
Sbjct 1624 QIIQKL 1629
>sp|Q5B4Z3|SEPH_EMENI Cytokinesis protein sepH OS=Emericella nidulans
(strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194
/ M139) OX=227321 GN=sepH PE=3 SV=2
Length=1346
Score = 106 bits (264), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 72/200 (36%), Positives = 100/200 (50%), Gaps = 23/200 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG G FG V Y N TGE VAVK +K AD EID+L+ L H +I+K
Sbjct 66 LGRGAFGSV----YRALNWNTGETVAVKQIKLADLPKSELRVIMLEIDLLKNLDHPNIVK 121
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY------LPRHSIGLAQLLLFAQQICEGMAYLH 1015
Y+G + ++L +++EY GSL P +G+ + Q+ G+ YLH
Sbjct 122 YQGFV--KSAETLNIILEYCENGSLHSIAKNFGRFPETLVGV-----YMSQVLHGLLYLH 174
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
Q IHRD+ N+L + LVK+ DFG+A E V +P +W APE ++
Sbjct 175 DQGVIHRDIKGANILTTKEGLVKLADFGVASRTTGLSESSVV----GTP-YWMAPEVIEL 229
Query 1076 YKFYYASDVWSFGVTLYELL 1095
ASD+WS G T+ ELL
Sbjct 230 SGATTASDIWSLGCTVIELL 249
Score = 66.2 bits (160), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 62/234 (26%), Positives = 99/234 (42%), Gaps = 32/234 (14%)
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
ELRV++ +D L+ + H ++ G ++ EY E+G L
Sbjct 100 ELRVIMLEID---------------LLKNLDHPNIVKYQGFVKSAETLNIILEYCENGSL 144
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+ + G P V Q+ L YL ++ ++H ++ G NIL + GL +
Sbjct 145 HS-IAKNFGRFPETLVGVYMSQVLHGLLYLHDQGVIHRDIKGANILTTKEGL-------V 196
Query 756 KLSDPGVG--LGALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGATLLEICFDGE 812
KL+D GV LS V W+APE + GA +TA D W G T++E+ +G+
Sbjct 197 KLADFGVASRTTGLSESSVVGTPYWMAPEVIELSGA---TTASDIWSLGCTVIEL-LEGK 252
Query 813 APLQSRSPSEKE-HFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
P + P H LP+ + P + QC +P R S R +L+
Sbjct 253 PPYYNLQPMPALFRIVNDDHPPLPQGASPAVKDFLMQCFQKDPNLRVSARKLLK 306
>sp|Q9SRH7|PBL35_ARATH Serine/threonine-protein kinase PBL35 OS=Arabidopsis
thaliana OX=3702 GN=PBL35 PE=1 SV=1
Length=490
Score = 103 bits (258), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 93/286 (33%), Positives = 135/286 (47%), Gaps = 28/286 (10%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LGEG FG V + P GTG VAVK L D G Q W EI+ L L H
Sbjct 142 LGEGGFGCVFKGWVEENGTAPVKPGTGLTVAVKTLNPD-GLQGHKEWLAEINYLGNLLHP 200
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLH 1015
+++K G C + ++ LV E++P GSL ++L R S+ L + + A +G+++LH
Sbjct 201 NLVKLVGYCIEDDQR--LLVYEFMPRGSLENHLFRRSLPLPWSIRMKIALGAAKGLSFLH 258
Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPE 1071
+ I+RD N+LLD + K+ DFGLAK P EG + R G + APE
Sbjct 259 EEALKPVIYRDFKTSNILLDGEYNAKLSDFGLAKDAPDEGKTHVSTRVMGT--YGYAAPE 316
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQ-MTVLRLTELLE 1129
+ SDV+SFGV L E+LT S ++ P L+ A+ + R LL+
Sbjct 317 YVMTGHLTSKSDVYSFGVVLLEMLTGRRSMDKNRPNGEHNLVEWARPHLLDKRRFYRLLD 376
Query 1130 RGERLPRPD-----KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
PR + K +V L C ++ RP ++ +LK
Sbjct 377 -----PRLEGHFSVKGAQKVTQLAAQCLSRDSKIRPKMSEVVEVLK 417
>sp|P53767|VGFR1_RAT Vascular endothelial growth factor receptor
1 OS=Rattus norvegicus OX=10116 GN=Flt1 PE=2 SV=1
Length=1336
Score = 105 bits (263), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 63/184 (34%), Positives = 98/184 (53%), Gaps = 16/184 (9%)
Query 988 DY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
DY + + + + L+ ++ Q+ GM +L ++ IHRDLAARN+LL + +VKI DFGLA
Sbjct 985 DYSEISKQPLTMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLA 1044
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + +Y R R D P+ W APE + + + SDVWS+GV L+E+ + S P
Sbjct 1045 RDIYKNPDYVR-RGDTRLPLKWMAPESIFDKVYSTKSDVWSYGVLLWEIFS-LGGSPYP- 1101
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
G+ + RL E G R+ P+ E+Y +M +CW + RP F L
Sbjct 1102 -------GVQMDEDFCSRLKE----GMRMRTPEYATPEIYQIMLDCWHKDPKERPRFAEL 1150
Query 1166 IPIL 1169
+ L
Sbjct 1151 VEKL 1154
Score = 54.7 bits (130), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 52/203 (26%), Positives = 83/203 (41%), Gaps = 33/203 (16%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V R
Sbjct 1005 QVARGMEFLSSRKCIHRDLAARNILLSE-------NNVVKICDFGLARDIYKNPDYVRRG 1057
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + ST D W +G L EI G +P E F R
Sbjct 1058 DTRLPLKWMAPESIFDKV--YSTKSDVWSYGVLLWEIFSLGGSPYPG--VQMDEDFCSRL 1113
Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN----------LA 875
+ R PE + P++ + C +P +RP F ++ L L N L
Sbjct 1114 KEGMRMRTPEYATPEIYQIMLDCWHKDPKERPRFAELVEKLGDLLQANVQQDGKDYIPLN 1173
Query 876 DVLTVNPDSPASDPTVFHKRYLK 898
+LT N S PT F + + K
Sbjct 1174 AILTRNSGFTYSVPT-FSEDFFK 1195
Score = 45.1 bits (105), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 46/166 (28%), Positives = 65/166 (39%), Gaps = 17/166 (10%)
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV--NPDSPASDPTV------ 891
+L TLT C+ I R L R D L++ +PD D
Sbjct 758 ELITLTCTCVAATLFWLLLTLFI-RKLKRSSSEVKTDYLSIIMDPDEVPLDEQCERLPYD 816
Query 892 -----FHKRYLKKIRDLGEGHFGK-VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
F + LK + LG G FGK V + T VAVK LK
Sbjct 817 ASKWEFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALM 876
Query 946 QEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
E+ IL + +H +++ G C QG L +++EY G+L +YL
Sbjct 877 TELKILTHIGHHLNVVNLLGACTKQG-GPLMVIVEYCKYGNLSNYL 921
>sp|O22042|M3K3_ARATH Mitogen-activated protein kinase kinase
kinase 3 OS=Arabidopsis thaliana OX=3702 GN=ANP3 PE=1 SV=1
Length=651
Score = 104 bits (260), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 59/202 (29%), Positives = 107/202 (53%), Gaps = 15/202 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-------KADCGPQHRSGWKQEIDILRTLY 955
+G G FG+V Y N +GE++A+K + + H ++E+ +L+ L
Sbjct 74 IGCGAFGRV----YMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLKNLS 129
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYL 1014
H +I++Y G + SL ++ME+VP GS+ L + S ++++ +Q+ G+ YL
Sbjct 130 HPNIVRYLGTVRES--DSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLGLEYL 187
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H +HRD+ N+L+DN +++ DFG +K V E + +P +W APE +
Sbjct 188 HNNGIMHRDIKGANILVDNKGCIRLADFGASKKVVELATVNGAKSMKGTP-YWMAPEVIL 246
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ +++D+WS G T+ E+ T
Sbjct 247 QTGHSFSADIWSVGCTVIEMAT 268
Score = 53.9 bits (128), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 55/218 (25%), Positives = 96/218 (44%), Gaps = 21/218 (10%)
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
E L+ +SH ++ G ++ E+V G + L + G P ++ +
Sbjct 120 EEVQLLKNLSHPNIVRYLGTVRESDSLNILMEFVPGGSISSLLEK-FGSFPEPVIIMYTK 178
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-----VGLGALSREE 771
QL L YL N ++H ++ G NIL+ G I+L+D G V L ++ +
Sbjct 179 QLLLGLEYLHNNGIMHRDIKGANILVDNKGC-------IRLADFGASKKVVELATVNGAK 231
Query 772 RVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL--QSRSPSEKEHFYQ 828
++ P W+APE + +S S D W G T++E+ G+ P Q + + H +
Sbjct 232 SMKGTPYWMAPEVILQTGHSFSA--DIWSVGCTVIEMA-TGKPPWSEQYQQFAAVLHIGR 288
Query 829 RQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ +PE P+ +CL EP+ R S +L+
Sbjct 289 TKAHPPIPEDLSPEAKDFLMKCLHKEPSLRLSATELLQ 326
>sp|P35969|VGFR1_MOUSE Vascular endothelial growth factor receptor
1 OS=Mus musculus OX=10090 GN=Flt1 PE=1 SV=1
Length=1333
Score = 105 bits (263), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 63/184 (34%), Positives = 98/184 (53%), Gaps = 16/184 (9%)
Query 988 DY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
DY + + + + L+ ++ Q+ GM +L ++ IHRDLAARN+LL + +VKI DFGLA
Sbjct 985 DYSEISKQPLTMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLA 1044
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + +Y R R D P+ W APE + + + SDVWS+GV L+E+ + S P
Sbjct 1045 RDIYKNPDYVR-RGDTRLPLKWMAPESIFDKVYSTKSDVWSYGVLLWEIFS-LGGSPYP- 1101
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
G+ + RL E G R+ P+ E+Y +M +CW + RP F L
Sbjct 1102 -------GVQMDEDFCSRLKE----GMRMRTPEYATPEIYQIMLDCWHKDPKERPRFAEL 1150
Query 1166 IPIL 1169
+ L
Sbjct 1151 VEKL 1154
Score = 55.1 bits (131), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 50/195 (26%), Positives = 79/195 (41%), Gaps = 32/195 (16%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V R
Sbjct 1005 QVARGMEFLSSRKCIHRDLAARNILLSE-------NNVVKICDFGLARDIYKNPDYVRRG 1057
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + ST D W +G L EI G +P E F R
Sbjct 1058 DTRLPLKWMAPESIFDKV--YSTKSDVWSYGVLLWEIFSLGGSPYPG--VQMDEDFCSRL 1113
Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN----------LA 875
+ R PE + P++ + C +P +RP F ++ L L N L
Sbjct 1114 KEGMRMRTPEYATPEIYQIMLDCWHKDPKERPRFAELVEKLGDLLQANVQQDGKDYIPLN 1173
Query 876 DVLTVNPDSPASDPT 890
+LT N S PT
Sbjct 1174 AILTRNSSFTYSTPT 1188
Score = 44.7 bits (104), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 46/166 (28%), Positives = 65/166 (39%), Gaps = 17/166 (10%)
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV--NPDSPASDPTV------ 891
+L TLT C+ I R L R D L++ +PD D
Sbjct 759 ELITLTCTCVAATLFWLLLTLFI-RKLKRSSSEVKTDYLSIIMDPDEVPLDEQCERLPYD 817
Query 892 -----FHKRYLKKIRDLGEGHFGK-VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
F + LK + LG G FGK V + T VAVK LK
Sbjct 818 ASKWEFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALM 877
Query 946 QEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
E+ IL + +H +++ G C QG L +++EY G+L +YL
Sbjct 878 TELKILTHIGHHLNVVNLLGACTKQG-GPLMVIVEYCKYGNLSNYL 922
>sp|O01798|SPE8_CAEEL Spermatocyte protein spe-8 OS=Caenorhabditis
elegans OX=6239 GN=spe-8 PE=1 SV=2
Length=512
Score = 103 bits (257), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 67/200 (34%), Positives = 107/200 (54%), Gaps = 11/200 (6%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG FG+V + VAVK L + + + +E +++ TL H ++
Sbjct 221 KKLGEGQFGEVHKGSLKTSVFAAPVTVAVKTLHQNHLSANEKILFLREANVMLTLSHPNV 280
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
IK+ G C ++ + +VME+ SL D L + +L+ G+ YLH +
Sbjct 281 IKFYGVC--TMKEPIMIVMEFCDGKSLEDALLSKEEKVSAEDKILYLFHAACGIDYLHGK 338
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLA-KAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+AARN LL++ +++KI DFGL+ K V + R+ G PV + APE LK+
Sbjct 339 QVIHRDIAARNCLLNSKKILKISDFGLSVKGVA-----IKERKGGCLPVKYMAPETLKKG 393
Query 1077 KFYYASDVWSFGVTLYELLT 1096
+ ASD++S+G +YE+ T
Sbjct 394 LYSTASDIYSYGALMYEVYT 413
Score = 72.8 bits (177), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 67/292 (23%), Positives = 128/292 (44%), Gaps = 39/292 (13%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
+++ +++T LG+G V++G L+ P + V +K
Sbjct 211 QLNNEQVTLNKKLGEGQFGEVHKGSLKTSVFAAP--------------------VTVAVK 250
Query 643 VLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
L +H + + F A++M +SH ++ +GVC ++V E+ + L+ L
Sbjct 251 TLHQNHLSANEKILFLREANVMLTLSHPNVIKFYGVCTMKEPIMIVMEFCDGKSLEDALL 310
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ V K++ A + YL K ++H ++ RN LL + +K+SD
Sbjct 311 SKEEKVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLL-------NSKKILKISDF 363
Query 761 GVGLGALSREERVER---IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
G+ + ++ +ER + ++APE L G STA D + +GA + E+ DG+ P ++
Sbjct 364 GLSVKGVAIKERKGGCLPVKYMAPETLKKGL--YSTASDIYSYGALMYEVYTDGKTPFET 421
Query 818 ---RSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILR 864
R ++ ++ L E P +A + Q YE R S + I++
Sbjct 422 CGLRGNELRKAIIGKRISLAVEVELPVFIANIFEQSRQYETEDRISSKQIIQ 473
>sp|Q55A09|Y9963_DICDI Probable serine/threonine-protein kinase
DDB_G0272254 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0272254
PE=3 SV=1
Length=1331
Score = 105 bits (263), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 82/295 (28%), Positives = 136/295 (46%), Gaps = 40/295 (14%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR---S 942
+S T+ + +K +++G+GHF KV + G+ VAVK L ++
Sbjct 1062 SSSVTMINYSDIKIDKEIGKGHFSKV------LKGNWKGKDVAVKKLNSNKDKAREEMIQ 1115
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIG 996
+K E+++L +L H +++ C + +VME++P G+L + + + SI
Sbjct 1116 EFKAEVELLGSLQHPNLV----TCYGYSLNPMCIVMEFLPSGNLFELIHSKPSEQQQSIK 1171
Query 997 LAQLLLFAQ--QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
L L+ A I GM +LH ++ IHRDL + N+L+D +KI D G+A+
Sbjct 1172 LDSTLILAIAFDIARGMQHLHTRNIIHRDLKSSNLLMDKHFNIKIADLGIARETSFTQTM 1231
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ V W APE L+ + +DV+S+ + LYELLT + Q GI
Sbjct 1232 TTI-----GTVAWTAPEILRHESYNQKADVYSYAIVLYELLTGEEPYQ----------GI 1276
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+L + +G R PD C L+ CW + + RP+FE + L
Sbjct 1277 PPMNAGIL----VASKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITNYL 1327
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 52/241 (22%), Positives = 92/241 (38%), Gaps = 35/241 (15%)
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D + ++ F L+ + H +L +G + +V E++ G L + +
Sbjct 1107 DKAREEMIQEFKAEVELLGSLQHPNLVTCYGYSLN--PMCIVMEFLPSGNLFELIHSKPS 1164
Query 705 HVPMAWKM------VVAQQLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEG 750
+ K+ +A +A + +L +N++H ++ N+L+ A LG+A
Sbjct 1165 EQQQSIKLDSTLILAIAFDIARGMQHLHTRNIIHRDLKSSNLLMDKHFNIKIADLGIARE 1224
Query 751 TSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
TS ++ G + W APE L S + D + + L E+
Sbjct 1225 TSFTQTMTTIGT-------------VAWTAPEILR--HESYNQKADVYSYAIVLYEL-LT 1268
Query 811 GEAPLQSRSPSEKEHFYQRQH---RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
GE P Q P + LP+ P L C + +P +RPSF I LT
Sbjct 1269 GEEPYQGIPPMNAGILVASKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITNYLT 1328
Query 868 R 868
+
Sbjct 1329 K 1329
>sp|P10533|RMIL_AVII1 Serine/threonine-protein kinase-transforming
protein Rmil OS=Avian retrovirus IC10 OX=11874 GN=V-RMIL
PE=3 SV=1
Length=367
Score = 101 bits (252), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 79/277 (29%), Positives = 123/277 (44%), Gaps = 41/277 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK L PQ +K E+ +LR H +I+
Sbjct 73 IGSGSFGTV----YKGKWHGD---VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 125
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + L +V ++ SL +L + +L+ A+Q +GM YLHA+
Sbjct 126 FMGYST---KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSI 182
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPE---GHEYYRVREDGDSPVFWYAPECLK-- 1074
IHRDL + N+ L D VKIGDFGLA H++ E + W APE ++
Sbjct 183 IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQF----EQLSGSILWMAPEVIRMQ 238
Query 1075 -EYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
+ + + SDV++FG+ LYEL+T + + + F+ G ++ +R
Sbjct 239 DKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVR------ 292
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
CP + LM C + + RP F ++
Sbjct 293 --------SNCPKAMKRLMAECLKKKRDERPLFPQIL 321
Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 58/244 (24%), Positives = 103/244 (42%), Gaps = 24/244 (10%)
Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+L V P+ + AF ++ + H ++ G + P+ +VT++ E L L
Sbjct 94 MLNVTAPTPQQLQ-AFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHL 151
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
M + +A+Q A + YL K+++H ++ NI L +K+ D
Sbjct 152 HIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE-------DLTVKIGD 204
Query 760 PGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGATLLEICFDGE 812
G+ G+ E+ I W+APE + N S D + FG L E+ G+
Sbjct 205 FGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYEL-MTGQ 263
Query 813 APLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQRPSFRTILRD 865
P + + ++ F R + P+ S CP+ + L ++CL + +RP F IL
Sbjct 264 LPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILAS 323
Query 866 LTRL 869
+ L
Sbjct 324 IELL 327
>sp|Q4WXY0|BCK1_ASPFU Mitogen-activated protein kinase kinae kinase
bck1 OS=Aspergillus fumigatus (strain ATCC MYA-4609 /
CBS 101355 / FGSC A1100 / Af293) OX=330879 GN=bck1 PE=3 SV=1
Length=1617
Score = 105 bits (263), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 67/207 (32%), Positives = 109/207 (53%), Gaps = 23/207 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK---------ADCGPQHRSGWKQEIDILRT 953
+G+G +G+V L N GE++AVK ++ D + + QEID ++
Sbjct 1329 IGKGTYGRVYLGI----NADNGEVLAVKQVEINPRLAGQDTDRVKEMVAAMDQEIDTMQH 1384
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012
L H +I++Y GC ++GE S+ + +EY+ GS+ L +H + + +Q G+A
Sbjct 1385 LEHPNIVQYLGC--ERGEFSISIYLEYISGGSIGSCLRKHGKFEESVVKSLTRQTLSGLA 1442
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE--GHEYYRVREDGDSPVFWYAP 1070
YLH Q +HRDL A N+LLD D KI DFG++K + G++ + VFW AP
Sbjct 1443 YLHDQGILHRDLKADNILLDLDGTCKISDFGISKKTDDIYGNDSSNSMQGS---VFWMAP 1499
Query 1071 ECLKEYKFYYAS--DVWSFGVTLYELL 1095
E ++ Y++ D+WS G + E+
Sbjct 1500 EVIQSQGQGYSAKVDIWSLGCVVLEMF 1526
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 44/172 (26%), Positives = 73/172 (42%), Gaps = 17/172 (10%)
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV-TEYVEHGPLDVWLRRERGHVPM 708
++ A + M + H ++ G C RG +I + EY+ G + LR+ G
Sbjct 1370 EMVAAMDQEIDTMQHLEHPNIVQYLG-CERGEFSISIYLEYISGGSIGSCLRKH-GKFEE 1427
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----- 763
+ + +Q S L+YL ++ ++H ++ NILL G K+SD G+
Sbjct 1428 SVVKSLTRQTLSGLAYLHDQGILHRDLKADNILLDLDGT-------CKISDFGISKKTDD 1480
Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G S + W+APE + S +D W G +LE+ F G P
Sbjct 1481 IYGNDSSNSMQGSVFWMAPEVIQSQGQGYSAKVDIWSLGCVVLEM-FAGRRP 1531
>sp|Q8I7I5|ROL3_CAEEL Protein roller-3 OS=Caenorhabditis elegans
OX=6239 GN=rol-3 PE=1 SV=2
Length=2481
Score = 105 bits (263), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 75/270 (28%), Positives = 129/270 (48%), Gaps = 28/270 (10%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VA+K LK + Q + + +E +L L H +I+K G C G++ +++EY+ G+L
Sbjct 1998 VAIKKLKPNHSFQEKMMFMKEAILLNNLDHPNIVKELGVCITPGQE--LILLEYMEGGNL 2055
Query 987 RDYLPRHSIGLAQ--------LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
+L + + Q LL + I GM YL ++H++L+AR LL V
Sbjct 2056 LKFLQKSTPNEYQSSELSPRDLLSISVDIARGMNYLERLPHVHKNLSARKCLLAGRPGVT 2115
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
+ G++K + G + R + V W APE LK+++F SDVW++GV LYE+ +
Sbjct 2116 KLEMGMSKELSNG-QVNRSDLENMEIVRWMAPEVLKDFQFSSKSDVWAYGVLLYEVFSFG 2174
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE-VYHLMKNCWETEAS 1157
+ + G R+ + G LP P CP + +Y ++K C ++++
Sbjct 2175 E--------------VPYGDKDNRRIMTDVRNGSVLPIPSYCPSKRIYKVIKQCLTSDST 2220
Query 1158 FRPTFENLIPILKTVHE--KYQGQAPSVFS 1185
R F ++ I +T + K Q P F+
Sbjct 2221 KRANFATILKIFETFRDDQKCQDDKPIQFN 2250
Score = 83.6 bits (205), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 71/247 (29%), Positives = 120/247 (49%), Gaps = 27/247 (11%)
Query 635 QELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+++RV +K L P+H + F + A L++ + H ++ GVC+ + +++ EY+E G
Sbjct 1994 KDVRVAIKKLKPNHSFQEKMMFMKEAILLNNLDHPNIVKELGVCITPGQELILLEYMEGG 2053
Query 694 PLDVWLRRERGHVPMAWK---------MVVAQQLASALSYLENKNLVHGNVCGRNILLA- 743
L +L++ P ++ + ++ +A ++YLE VH N+ R LLA
Sbjct 2054 NLLKFLQKS---TPNEYQSSELSPRDLLSISVDIARGMNYLERLPHVHKNLSARKCLLAG 2110
Query 744 RLGLAE---GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800
R G+ + G S +LS+ V L E +E + W+APE L S+ D W +
Sbjct 2111 RPGVTKLEMGMSK--ELSNGQVNRSDL---ENMEIVRWMAPEVLKDF--QFSSKSDVWAY 2163
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP--QLATLTSQCLTYEPTQRP 857
G L E+ GE P + + LP PS CP ++ + QCLT + T+R
Sbjct 2164 GVLLYEVFSFGEVPYGDKDNRRIMTDVRNGSVLPIPSYCPSKRIYKVIKQCLTSDSTKRA 2223
Query 858 SFRTILR 864
+F TIL+
Sbjct 2224 NFATILK 2230
>sp|B0XXN8|BCK1_ASPFC Mitogen-activated protein kinase kinae kinase
bck1 OS=Aspergillus fumigatus (strain CBS 144.89 / FGSC
A1163 / CEA10) OX=451804 GN=bck1 PE=3 SV=1
Length=1617
Score = 105 bits (263), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 67/207 (32%), Positives = 109/207 (53%), Gaps = 23/207 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK---------ADCGPQHRSGWKQEIDILRT 953
+G+G +G+V L N GE++AVK ++ D + + QEID ++
Sbjct 1329 IGKGTYGRVYLGI----NADNGEVLAVKQVEINPRLAGQDTDRVKEMVAAMDQEIDTMQH 1384
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012
L H +I++Y GC ++GE S+ + +EY+ GS+ L +H + + +Q G+A
Sbjct 1385 LEHPNIVQYLGC--ERGEFSISIYLEYISGGSIGSCLRKHGKFEESVVKSLTRQTLSGLA 1442
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE--GHEYYRVREDGDSPVFWYAP 1070
YLH Q +HRDL A N+LLD D KI DFG++K + G++ + VFW AP
Sbjct 1443 YLHDQGILHRDLKADNILLDLDGTCKISDFGISKKTDDIYGNDSSNSMQGS---VFWMAP 1499
Query 1071 ECLKEYKFYYAS--DVWSFGVTLYELL 1095
E ++ Y++ D+WS G + E+
Sbjct 1500 EVIQSQGQGYSAKVDIWSLGCVVLEMF 1526
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 44/172 (26%), Positives = 73/172 (42%), Gaps = 17/172 (10%)
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV-TEYVEHGPLDVWLRRERGHVPM 708
++ A + M + H ++ G C RG +I + EY+ G + LR+ G
Sbjct 1370 EMVAAMDQEIDTMQHLEHPNIVQYLG-CERGEFSISIYLEYISGGSIGSCLRKH-GKFEE 1427
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----- 763
+ + +Q S L+YL ++ ++H ++ NILL G K+SD G+
Sbjct 1428 SVVKSLTRQTLSGLAYLHDQGILHRDLKADNILLDLDGT-------CKISDFGISKKTDD 1480
Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G S + W+APE + S +D W G +LE+ F G P
Sbjct 1481 IYGNDSSNSMQGSVFWMAPEVIQSQGQGYSAKVDIWSLGCVVLEM-FAGRRP 1531
>sp|Q9DE49|PGFRA_DANRE Platelet-derived growth factor receptor
alpha OS=Danio rerio OX=7955 GN=pdgfra PE=2 SV=1
Length=1059
Score = 105 bits (261), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 59/168 (35%), Positives = 88/168 (52%), Gaps = 16/168 (10%)
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
LL F Q+ GM +L +++ +HRDLAARNVLL ++VKI DFGLA+ + + Y +
Sbjct 766 DLLSFTYQVARGMEFLASKNCVHRDLAARNVLLSQGKIVKICDFGLARDIMHDNNYVS-K 824
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
PV W APE + + + SDVWS+G+ L+E+ + L G
Sbjct 825 GSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFS--------------LGGTPYPG 870
Query 1119 MTV-LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
M V ++ G R+ +P+ +VY LM CW +E RP+F +L
Sbjct 871 MVVDSSFYNKIKSGYRMTKPEHASSDVYELMMKCWNSEPEKRPSFHSL 918
Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 44/166 (27%), Positives = 73/166 (44%), Gaps = 22/166 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L +KN VH ++ RN+LL++ +K+ D G+ + V +
Sbjct 773 QVARGMEFLASKNCVHRDLAARNVLLSQ-------GKIVKICDFGLARDIMHDNNYVSKG 825
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + N +T D W +G L EI G P FY +
Sbjct 826 STFLPVKWMAPESI--FDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMVVDSS--FYNKI 881
Query 830 --QHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
+R+ PE + + L +C EP +RPSF ++ + L P
Sbjct 882 KSGYRMTKPEHASSDVYELMMKCWNSEPEKRPSFHSLSDTVASLLP 927
>sp|P23561|STE11_YEAST Serine/threonine-protein kinase STE11 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=STE11 PE=1 SV=3
Length=717
Score = 104 bits (259), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 53/155 (34%), Positives = 88/155 (57%), Gaps = 3/155 (2%)
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL 1002
+ E+++L+ L+HE+I+ Y G ++ G +L + +EYVP GS+ L + L+
Sbjct 500 ALQHEMNLLKELHHENIVTYYGASQEGG--NLNIFLEYVPGGSVSSMLNNYGPFEESLIT 557
Query 1003 -FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
F +QI G+AYLH ++ IHRD+ N+L+D VKI DFG++K + ++ R
Sbjct 558 NFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASL 617
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
VFW +PE +K+ +D+WS G + E+ T
Sbjct 618 QGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFT 652
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 39/177 (22%), Positives = 78/177 (44%), Gaps = 22/177 (12%)
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
H + A +L+ ++ H ++ +G G + EYV G + L + P
Sbjct 494 HRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLN---NYGP 550
Query 708 MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763
++ +Q+ ++YL KN++H ++ G NIL+ G +K++D G+
Sbjct 551 FEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGC-------VKITDFGISKK 603
Query 764 LGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
L L++++ + W++PE + A + D W G ++E+ F G+ P
Sbjct 604 LSPLNKKQNKRASLQGSVFWMSPEVVKQTAT--TAKADIWSTGCVVIEM-FTGKHPF 657
>sp|A7A1P0|STE11_YEAS7 Serine/threonine-protein kinase STE11 OS=Saccharomyces
cerevisiae (strain YJM789) OX=307796 GN=STE11
PE=3 SV=1
Length=717
Score = 104 bits (259), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 53/155 (34%), Positives = 88/155 (57%), Gaps = 3/155 (2%)
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL 1002
+ E+++L+ L+HE+I+ Y G ++ G +L + +EYVP GS+ L + L+
Sbjct 500 ALQHEMNLLKELHHENIVTYYGASQEGG--NLNIFLEYVPGGSVSSMLNNYGPFEESLIT 557
Query 1003 -FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
F +QI G+AYLH ++ IHRD+ N+L+D VKI DFG++K + ++ R
Sbjct 558 NFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASL 617
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
VFW +PE +K+ +D+WS G + E+ T
Sbjct 618 QGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFT 652
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 39/177 (22%), Positives = 78/177 (44%), Gaps = 22/177 (12%)
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
H + A +L+ ++ H ++ +G G + EYV G + L + P
Sbjct 494 HRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLN---NYGP 550
Query 708 MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763
++ +Q+ ++YL KN++H ++ G NIL+ G +K++D G+
Sbjct 551 FEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGC-------VKITDFGISKK 603
Query 764 LGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
L L++++ + W++PE + A + D W G ++E+ F G+ P
Sbjct 604 LSPLNKKQNKRASLQGSVFWMSPEVVKQTAT--TAKADIWSTGCVVIEM-FTGKHPF 657
>sp|Q61846|MELK_MOUSE Maternal embryonic leucine zipper kinase
OS=Mus musculus OX=10090 GN=Melk PE=1 SV=2
Length=643
Score = 103 bits (258), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 72/204 (35%), Positives = 111/204 (54%), Gaps = 12/204 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+Y + +G G F KV L C+ T GEMVA+K + + K EID L++L
Sbjct 9 KYYELYETIGTGGFAKVKLACHVLT----GEMVAIKIMDKNALGSDLPRVKTEIDALKSL 64
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAY 1013
H+HI + E + + + +V+EY P G L DY+ + + + + +QI +AY
Sbjct 65 RHQHICQLYHVLETKNK--IFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAY 122
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+H+Q Y HRDL N+L D + +K+ DFGL A P+G++ Y ++ S + + APE L
Sbjct 123 VHSQGYAHRDLKPENLLFDENHKLKLIDFGLC-AKPKGNKDYHLQTCCGS-LAYAAPE-L 179
Query 1074 KEYKFYYAS--DVWSFGVTLYELL 1095
+ K Y S DVWS G+ LY L+
Sbjct 180 IQGKSYLGSEADVWSMGILLYVLM 203
>sp|Q54H45|DRKB_DICDI Probable serine/threonine-protein kinase
drkB OS=Dictyostelium discoideum OX=44689 GN=drkB PE=3 SV=1
Length=690
Score = 104 bits (259), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 84/280 (30%), Positives = 136/280 (49%), Gaps = 36/280 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGT--GEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHI 959
+G+G+FG+V L GT G VAVK L A + + +EI++++ L H ++
Sbjct 397 IGKGNFGEVYL--------GTWRGSQVAVKKLPAHNINENILKEFHREINLMKNLRHPNV 448
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI--CEGMAYLHAQ 1017
I++ G C + + + EY+P GSL L I ++ L+ I +G+ YLH
Sbjct 449 IQFLGSCLISPD--ICICTEYMPRGSLYSILHNEKIKISWSLVKRMMIDAAKGIIYLHGS 506
Query 1018 H--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRDL + N+L+D + VK+ DFGL+ +G +P W +PE L+
Sbjct 507 TPVILHRDLKSHNLLVDENWKVKVADFGLSTIEQQG----ATMTACGTPC-WTSPEVLRS 561
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
++ +DV+SFG+ L+E C + Q P GI Q+ + + G R P
Sbjct 562 QRYTEKADVYSFGIILWE----CATRQDP------YFGIPPFQV----IFAVGREGMRPP 607
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
P P + L+K+C S RPT E + IL+++ K
Sbjct 608 TPKYGPPKYIQLLKDCLNENPSQRPTMEQCLEILESIETK 647
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 62/262 (24%), Positives = 109/262 (42%), Gaps = 31/262 (12%)
Query 630 GRDRGQELRVVLKVLDPSHH---DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
G RG + V +K L P+H+ +I F+ +LM + H ++ G C+ P+ +
Sbjct 408 GTWRGSQ--VAVKKL-PAHNINENILKEFHREINLMKNLRHPNVIQFLGSCLISPDICIC 464
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQL--ASALSYLENKN--LVHGNVCGRNILL 742
TEY+ G L L E+ + ++W +V + A + YL ++H ++ N+L+
Sbjct 465 TEYMPRGSLYSILHNEK--IKISWSLVKRMMIDAAKGIIYLHGSTPVILHRDLKSHNLLV 522
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKW 798
+ +K++D GL + ++ W +PE L + + D +
Sbjct 523 DE-------NWKVKVAD--FGLSTIEQQGATMTACGTPCWTSPEVLR--SQRYTEKADVY 571
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSC--PQLATLTSQCLTYEPTQ 855
FG L E C + P P + R+ R P P P+ L CL P+Q
Sbjct 572 SFGIILWE-CATRQDPYFGIPPFQVIFAVGREGMRPPTPKYGPPKYIQLLKDCLNENPSQ 630
Query 856 RPSFRTILRDLTRLQPHNLADV 877
RP+ L L ++ D+
Sbjct 631 RPTMEQCLEILESIETKGFDDI 652
>sp|O24527|SIK1_ARATH Serine/threonine-protein kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=SIK1 PE=1 SV=1
Length=836
Score = 104 bits (260), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 84/306 (27%), Positives = 136/306 (44%), Gaps = 31/306 (10%)
Query 865 DLTRLQPHNLADVLTVNPDSPA-SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923
D ++Q N T PDS DPT ++ + +LG+G +G V Y + T
Sbjct 220 DNRKMQQQNSKMSTTSLPDSITREDPTTKYEF----LNELGKGSYGSV----YKARDLKT 271
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
E+VAVK + G + + EI++L+ H ++++Y G QGE L +VMEY
Sbjct 272 SEIVAVKVISLTEGEEGYEEIRGEIEMLQQCNHPNVVRYLGSY--QGEDYLWIVMEYCGG 329
Query 984 GSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
GS+ D + ++ Q+ ++ +G+AYLH+ + +HRD+ N+LL VK+GD
Sbjct 330 GSVADLMNVTEEALEEYQIAYICREALKGLAYLHSIYKVHRDIKGGNILLTEQGEVKLGD 389
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FG+A + R W APE ++E ++ DVW+ GV+ E+
Sbjct 390 FGVAAQLT---RTMSKRNTFIGTPHWMAPEVIQENRYDGKVDVWALGVSAIEMAEGLPPR 446
Query 1102 QSP-PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
S P + L +I I M L +K + + C E RP
Sbjct 447 SSVHPMRVLFMISIEPAPM--------------LEDKEKWSLVFHDFVAKCLTKEPRLRP 492
Query 1161 TFENLI 1166
T ++
Sbjct 493 TAAEML 498
Score = 37.7 bits (86), Expect = 0.77, Method: Compositional matrix adjust.
Identities = 41/162 (25%), Positives = 64/162 (40%), Gaps = 24/162 (15%)
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG---ALSRE 770
+ ++ L+YL + VH ++ G NILL G +KL D GV +S+
Sbjct 351 ICREALKGLAYLHSIYKVHRDIKGGNILLTEQG-------EVKLGDFGVAAQLTRTMSKR 403
Query 771 ERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
P W+APE + N +D W G + +E+ +G P S P
Sbjct 404 NTFIGTPHWMAPEVIQ--ENRYDGKVDVWALGVSAIEMA-EGLPPRSSVHPMRVLFMISI 460
Query 830 QHRLPEPSCPQ-------LATLTSQCLTYEPTQRPSFRTILR 864
+ P P ++CLT EP RP+ +L+
Sbjct 461 E---PAPMLEDKEKWSLVFHDFVAKCLTKEPRLRPTAAEMLK 499
>sp|O08775|VGFR2_RAT Vascular endothelial growth factor receptor
2 OS=Rattus norvegicus OX=10116 GN=Kdr PE=1 SV=1
Length=1343
Score = 105 bits (261), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 69/197 (35%), Positives = 102/197 (52%), Gaps = 20/197 (10%)
Query 971 EKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029
EKSL V E L +D+L L L+ ++ Q+ +GM +L ++ IHRDLAARN+
Sbjct 976 EKSLSDVEEEEASEELYKDFLT-----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNI 1030
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
LL +VKI DFGLA+ + + +Y R + D P+ W APE + + + S VWSFGV
Sbjct 1031 LLSEKNVVKICDFGLARDIYKDPDYVR-KGDPRLPLKWMAPETIFDRIYTIQSGVWSFGV 1089
Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149
L+E+ + +S P K E + L+ G R+ PD E+Y M
Sbjct 1090 LLWEIFS-LGASPYPGVKIDE------------KFCRRLKEGTRMRAPDYTTPEMYQTML 1136
Query 1150 NCWETEASFRPTFENLI 1166
+CW + + RP F L+
Sbjct 1137 DCWHEDPNQRPAFSELV 1153
Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 47/197 (24%), Positives = 85/197 (43%), Gaps = 34/197 (17%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V +
Sbjct 1007 QVAKGMEFLASRKCIHRDLAARNILLSEKNV-------VKICDFGLARDIYKDPDYVRKG 1059
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + ++ + + W FG L EI G +P EK F +R
Sbjct 1060 DPRLPLKWMAPETIFDRIYTIQSGV--WSFGVLLWEIFSLGASPYPGVKIDEK--FCRRL 1115
Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN------------ 873
+ R P+ + P++ C +P QRP+F ++ L L N
Sbjct 1116 KEGTRMRAPDYTTPEMYQTMLDCWHEDPNQRPAFSELVEHLGNLLQANAQQDGKDYIVLP 1175
Query 874 LADVLTVNPDSPASDPT 890
+++ L++ DS S PT
Sbjct 1176 MSETLSMEEDSGLSLPT 1192
>sp|Q54RB7|SHKA_DICDI Dual specificity protein kinase shkA OS=Dictyostelium
discoideum OX=44689 GN=shkA PE=2 SV=1
Length=527
Score = 103 bits (256), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 73/276 (26%), Positives = 127/276 (46%), Gaps = 29/276 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEM--VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG+G FG V G + VAVK + + + +++E+ I+ ++H +I+
Sbjct 51 LGDGSFGTVY--------KGRCRLKDVAVKVMLKQVDQKTLTDFRKEVAIMSKIFHPNIV 102
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ G C K L + E + G+L L P + L + A+ G+ +LH+ +
Sbjct 103 LFLGACTSTPGK-LMICTELMK-GNLESLLLDPMVKLPLITRMRMAKDAALGVLWLHSSN 160
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+IHRDL N+L+D + VK+ DFGL++ G ++ W APE L+
Sbjct 161 PVFIHRDLKTSNLLVDANLTVKVCDFGLSQIKQRGENLKDGQDGAKGTPLWMAPEVLQGR 220
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
F +DV+SFG+ L+++ T + F + I + Q+ R
Sbjct 221 LFNEKADVYSFGLVLWQIFTRQELFPEFDNFFKFVAAICEKQL-------------RPSI 267
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
PD CP + L++ CW+ RP+FE ++ L+ +
Sbjct 268 PDDCPKSLKELIQKCWDPNPEVRPSFEGIVSELEEI 303
Score = 62.0 bits (149), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 71/299 (24%), Positives = 125/299 (42%), Gaps = 48/299 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ + EIT S LG G+ VY+GR R++ ++V+LK
Sbjct 40 ISETEITTESILGDGSFGTVYKGRCRLKDVA----------------------VKVMLKQ 77
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+D F + ++MS++ H ++ G C P +M+ + G L+ L
Sbjct 78 VD---QKTLTDFRKEVAIMSKIFHPNIVLFLGACTSTPGKLMICTELMKGNLESLLLDPM 134
Query 704 GHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILL-ARLGLAEGTSPFIKLSDP 760
+P+ +M +A+ A + +L + N +H ++ N+L+ A L + ++
Sbjct 135 VKLPLITRMRMAKDAALGVLWLHSSNPVFIHRDLKTSNLLVDANLTVKVCDFGLSQIKQR 194
Query 761 GVGLGALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
G L ++ + P W+APE L G + D + FG L +I Q
Sbjct 195 GENLK--DGQDGAKGTPLWMAPEVLQG--RLFNEKADVYSFGLVLWQI-----FTRQELF 245
Query 820 PSEKEHFY-------QRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
P E ++F+ ++Q R P CP+ L L +C P RPSF I+ +L +
Sbjct 246 P-EFDNFFKFVAAICEKQLRPSIPDDCPKSLKELIQKCWDPNPEVRPSFEGIVSELEEI 303
>sp|P35917|VGFR3_MOUSE Vascular endothelial growth factor receptor
3 OS=Mus musculus OX=10090 GN=Flt4 PE=1 SV=1
Length=1363
Score = 104 bits (260), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 58/175 (33%), Positives = 94/175 (54%), Gaps = 14/175 (8%)
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ + L+ ++ Q+ GM +L ++ IHRDLAARN+LL +VKI DFGLA+ + + +Y
Sbjct 1009 LTMEDLVCYSFQVARGMEFLASRKCIHRDLAARNILLSESDIVKICDFGLARDIYKDPDY 1068
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
R + P+ W APE + + + SDVWSFGV L+E+ + +S P + E
Sbjct 1069 VR-KGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFS-LGASPYPGVQINE---- 1122
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ L+ G R+ P+ + H+M++CW + RP F +L+ IL
Sbjct 1123 --------EFCQRLKDGTRMRAPELATPAIRHIMQSCWSGDPKARPAFSDLVEIL 1169
Score = 56.6 bits (135), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 43/164 (26%), Positives = 73/164 (45%), Gaps = 22/164 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L ++ +H ++ RNILL+ S +K+ D G+ + V +
Sbjct 1020 QVARGMEFLASRKCIHRDLAARNILLSE-------SDIVKICDFGLARDIYKDPDYVRKG 1072
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + +T D W FG L EI G +P +E+ F QR
Sbjct 1073 SARLPLKWMAPESIFDKV--YTTQSDVWSFGVLLWEIFSLGASPYPGVQINEE--FCQRL 1128
Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ R PE + P + + C + +P RP+F ++ L L
Sbjct 1129 KDGTRMRAPELATPAIRHIMQSCWSGDPKARPAFSDLVEILGDL 1172
>sp|Q91ZT1|VGFR3_RAT Vascular endothelial growth factor receptor
3 OS=Rattus norvegicus OX=10116 GN=Flt4 PE=1 SV=1
Length=1363
Score = 104 bits (260), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 58/175 (33%), Positives = 94/175 (54%), Gaps = 14/175 (8%)
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ + L+ ++ Q+ GM +L ++ IHRDLAARN+LL +VKI DFGLA+ + + +Y
Sbjct 1009 LTMEDLVCYSFQVARGMEFLASRKCIHRDLAARNILLSESDIVKICDFGLARDIYKDPDY 1068
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
R + P+ W APE + + + SDVWSFGV L+E+ + +S P + E
Sbjct 1069 VR-KGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFS-LGASPYPGVQINE---- 1122
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ L+ G R+ P+ + H+M++CW + RP F +L+ IL
Sbjct 1123 --------EFCQRLKDGTRMRAPELATPAIRHIMQSCWSGDPKARPAFSDLVEIL 1169
Score = 56.6 bits (135), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 43/164 (26%), Positives = 73/164 (45%), Gaps = 22/164 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L ++ +H ++ RNILL+ S +K+ D G+ + V +
Sbjct 1020 QVARGMEFLASRKCIHRDLAARNILLSE-------SDIVKICDFGLARDIYKDPDYVRKG 1072
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + +T D W FG L EI G +P +E+ F QR
Sbjct 1073 SARLPLKWMAPESIFDKV--YTTQSDVWSFGVLLWEIFSLGASPYPGVQINEE--FCQRL 1128
Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ R PE + P + + C + +P RP+F ++ L L
Sbjct 1129 KDGTRMRAPELATPAIRHIMQSCWSGDPKARPAFSDLVEILGDL 1172
>sp|Q10056|SHK2_SCHPO Serine/threonine-protein kinase shk2 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=shk2 PE=3 SV=1
Length=589
Score = 103 bits (257), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 78/249 (31%), Positives = 122/249 (49%), Gaps = 17/249 (7%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS-DPTVFHKRYLKKIRDLGEGH 907
+T P + S T+ R +T Q L + DS S DP Y LG+G
Sbjct 270 VTKVPVKADSKNTLSRRMTDRQA------LAMLKDSVTSHDPV----EYFNVKHKLGQGA 319
Query 908 FGKVSL-YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC 966
G V L G + VA+K++ C + + EI ++R H +I+ Y
Sbjct 320 SGSVYLAKVVGGKQLGIFDSVAIKSIDLQCQTR-KELILNEITVMRESIHPNIVTYLDSF 378
Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
+ E+ L +VMEY+ GSL D + + + AQ+ + C+G+ +LHA++ IHRD+ +
Sbjct 379 LVR-ERHLWVVMEYMNAGSLTDIIEKSKLTEAQIARICLETCKGIQHLHARNIIHRDIKS 437
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
NVLLDN +KI DFG A RV G +P +W APE +K+ ++ D+WS
Sbjct 438 DNVLLDNSGNIKITDFGFC-ARLSNRTNKRVTMVG-TP-YWMAPEVVKQNEYGTKVDIWS 494
Query 1087 FGVTLYELL 1095
G+ + E++
Sbjct 495 LGIMIIEMI 503
Score = 43.9 bits (102), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 57/278 (21%), Positives = 105/278 (38%), Gaps = 40/278 (14%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LGQG +VY ++ V G+ G V +K +D
Sbjct 315 LGQGASGSVYLAKV-------------------VGGKQLGIFDSVAIKSIDLQCQTRKEL 355
Query 655 FYETASLMSQVSHTHL-AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
++M + H ++ ++ VR +V EY+ G L + E+ + A
Sbjct 356 ILNEITVMRESIHPNIVTYLDSFLVRERHLWVVMEYMNAGSLTDII--EKSKLTEAQIAR 413
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-EER 772
+ + + +L +N++H ++ N+LL G IK++D G +R +R
Sbjct 414 ICLETCKGIQHLHARNIIHRDIKSDNVLLDNSG-------NIKITDFGFCARLSNRTNKR 466
Query 773 VERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
V + W+APE + N T +D W G ++E+ + E P P + +
Sbjct 467 VTMVGTPYWMAPEVVK--QNEYGTKVDIWSLGIMIIEM-IENEPPYLREDPIRALYLIAK 523
Query 830 QH----RLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
+ P L + + CLT + R + +L
Sbjct 524 NGTPTLKKPNLVSKNLKSFLNSCLTIDTIFRATAAELL 561
>sp|Q55FT4|TSUA_DICDI Probable serine/threonine-protein kinase
tsuA OS=Dictyostelium discoideum OX=44689 GN=tsuA PE=1 SV=1
Length=2247
Score = 105 bits (261), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 67/203 (33%), Positives = 106/203 (52%), Gaps = 16/203 (8%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYH 956
K I +GEG FGKV Y TG++VA K + K + +QEIDIL+ L H
Sbjct 6 KLIGQIGEGSFGKV----YKYRKKFTGQLVACKVISKKGKNEEDILSLRQEIDILKNLSH 61
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAY 1013
+II++ C E++ E LV EY G L + S+ L Q + + Q+ + Y
Sbjct 62 PNIIQFISCFENKNE--FTLVTEYAD-GDLSQIISEEKTLSVDLIQSICY--QLVIALNY 116
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
LH + IHRD+ +N+L+ + +K+ DFG AK + + +P++ APE +
Sbjct 117 LHYKKVIHRDIKPQNILITSGGQIKVCDFGFAKTISSNS--ILLTSLKGTPLYL-APEII 173
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
+E + Y +D+WS G+ LY++L
Sbjct 174 QEQPYDYKADLWSLGIILYQILV 196
Score = 40.4 bits (93), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 49/211 (23%), Positives = 84/211 (40%), Gaps = 19/211 (9%)
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
L+ + ++ +SH ++ E +VTEY + G L + E+ + +
Sbjct 47 LSLRQEIDILKNLSHPNIIQFISCFENKNEFTLVTEYAD-GDLSQIISEEKT-LSVDLIQ 104
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
+ QL AL+YL K ++H ++ +NIL+ G IK+ D G S
Sbjct 105 SICYQLVIALNYLHYKKVIHRDIKPQNILITSGGQ-------IKVCDFGFAKTISSNSIL 157
Query 773 VERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF-Y 827
+ + +LAPE + D W G L +I G P + S ++ H
Sbjct 158 LTSLKGTPLYLAPEII--QEQPYDYKADLWSLGIILYQILV-GSPPFSANSLADLVHMTL 214
Query 828 QRQHRLPEP--SCPQLATLTSQCLTYEPTQR 856
+ +P+ P L +L Q L P +R
Sbjct 215 ESNIEIPKELNKYPDLVSLFRQLLCKNPDKR 245
>sp|P27636|CDC15_YEAST Cell division control protein 15 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=CDC15 PE=1 SV=3
Length=974
Score = 104 bits (259), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 77/238 (32%), Positives = 119/238 (50%), Gaps = 26/238 (11%)
Query 872 HNLADVLTVN--PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+++AD VN P AS+ +V + +LK++ +G G +G V Y N T ++VA+
Sbjct 2 NSMADTDRVNLTPIQRASEKSV--QYHLKQV--IGRGSYGVV----YKAINKHTDQVVAI 53
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K + + + + EI +L+ L H +I+KY G E L +++EY GSLR
Sbjct 54 KEVVYE-NDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYE--LYILLEYCANGSLRRL 110
Query 990 LPRHSIGLAQ--LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
+ R S GL++ + Q G+ YLH + IHRD+ A N+LL D VK+ DFG++
Sbjct 111 ISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTI 170
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
V + W APE L SD+WS G T+ E+LT ++PP
Sbjct 171 VNSSALTLA------GTLNWMAPEILGNRGASTLSDIWSLGATVVEMLT-----KNPP 217
Score = 60.1 bits (144), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 51/207 (25%), Positives = 88/207 (43%), Gaps = 12/207 (6%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
SL+ ++H ++ HG + E ++ EY +G L + R + Q
Sbjct 72 SLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTL 131
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPW 778
L YL + ++H ++ NILL+ A+ T +KL+D GV S + + W
Sbjct 132 LGLKYLHGEGVIHRDIKAANILLS----ADNT---VKLADFGVSTIVNSSALTLAGTLNW 184
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838
+APE L G ST D W GAT++E+ P + + + + + P S
Sbjct 185 MAPEIL--GNRGASTLSDIWSLGATVVEM-LTKNPPYHNLTDANIYYAVENDTYYPPSSF 241
Query 839 PQ-LATLTSQCLTYEPTQRPSFRTILR 864
+ L S+C +RP+ +L+
Sbjct 242 SEPLKDFLSKCFVKNMYKRPTADQLLK 268
>sp|Q00342|FLT3_MOUSE Receptor-type tyrosine-protein kinase FLT3
OS=Mus musculus OX=10090 GN=Flt3 PE=1 SV=2
Length=1000
Score = 104 bits (259), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 60/177 (34%), Positives = 94/177 (53%), Gaps = 18/177 (10%)
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ LL FA Q+ +GM +L + +HRDLAARNVL+ + ++VKI DFGLA+ + Y
Sbjct 786 LTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDILSDSSY 845
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
VR + PV W APE L E + SDVWS+G+ L+E+ + +G+
Sbjct 846 V-VRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFS---------------LGV 889
Query 1115 A--QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
G +L++ G ++ +P +Y +M++CW ++ RP+F NL L
Sbjct 890 NPYPGIPVDANFYKLIQSGFKMEQPFYATEGIYFVMQSCWAFDSRKRPSFPNLTSFL 946
Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 42/159 (26%), Positives = 71/159 (45%), Gaps = 22/159 (14%)
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771
+ A Q+A + +LE K+ VH ++ RN+L+ +K+ D G+ LS
Sbjct 792 LCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTH-------GKVVKICDFGLARDILSDSS 844
Query 772 RVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
V R + W+APE L G ++ + D W +G L EI G P P + +
Sbjct 845 YVVRGNARLPVKWMAPESLFEGIYTIKS--DVWSYGILLWEIFSLGVNPYPG-IPVDA-N 900
Query 826 FY---QRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSF 859
FY Q ++ +P + + + C ++ +RPSF
Sbjct 901 FYKLIQSGFKMEQPFYATEGIYFVMQSCWAFDSRKRPSF 939
>sp|P00532|RAF_MSV36 Serine/threonine-protein kinase-transforming
protein raf OS=Murine sarcoma virus 3611 OX=11812 GN=V-RAF
PE=3 SV=1
Length=323
Score = 99.8 bits (247), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 79/276 (29%), Positives = 127/276 (46%), Gaps = 39/276 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+
Sbjct 30 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILL 82
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++
Sbjct 83 FMGYMT---KDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 139
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076
IHRD+ + N+ L VKIGDFGLA +V + S V W APE ++ +
Sbjct 140 IHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-VLWMAPEVIRMQDDN 198
Query 1077 KFYYASDVWSFGVTLYELL------THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
F + SDV+S+G+ LYEL+ H ++ + + ++G + RL +
Sbjct 199 PFSFQSDVYSYGIVLYELMAGELPYAHINNRD----QIIFMVGRGYASPDLSRLYK---- 250
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
CP + L+ +C + RP F ++
Sbjct 251 --------NCPKAIKRLVADCVKKVKEERPLFPQIL 278
Score = 62.8 bits (151), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 67/269 (25%), Positives = 119/269 (44%), Gaps = 27/269 (10%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688
G+ G +LKV+DP+ + AF +++ + H ++ G + +N+ +VT+
Sbjct 41 GKWHGDVAVKILKVVDPTPEQLQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 97
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ E L L + M + +A+Q A + YL KN++H ++ NI L
Sbjct 98 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF-----LH 152
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECL-PGGANSLSTAMDKWGFG 801
EG + +K+ D G+ G+ E+ + W+APE + N S D + +G
Sbjct 153 EGLT--VKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYG 210
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQ-RQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854
L E+ GE P + ++ F R + P+ S CP+ + L + C+
Sbjct 211 IVLYEL-MAGELPYAHINNRDQIIFMVGRGYASPDLSRLYKNCPKAIKRLVADCVKKVKE 269
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPD 883
+RP F IL + LQ H+L + P+
Sbjct 270 ERPLFPQILSSIELLQ-HSLPKINRSAPE 297
>sp|F4JPX3|PBL20_ARATH Probable serine/threonine-protein kinase
PBL20 OS=Arabidopsis thaliana OX=3702 GN=PBL20 PE=3 SV=1
Length=388
Score = 100 bits (250), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 96/296 (32%), Positives = 133/296 (45%), Gaps = 30/296 (10%)
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR--PSFRTILRDLTRLQPHN 873
+SR EKE R + S P+L T + PT R PS T ++DL + N
Sbjct 13 KSRGNMEKEKKNIRGREFLQKSAPELTTRKTTLSFNLPTPRSLPS-PTSIKDLYTDREQN 71
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE------MV 927
L V SD T R LK +GEG FG S+Y N G+ V
Sbjct 72 QNQNLRVFSFKELSDATCEFSRKLK----IGEGGFG--SVYKATINNPTVGDSHSSPLTV 125
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
AVK L H+ W E+ L + H ++++ G C + E+ LV E + SL
Sbjct 126 AVKKLNRQSLQGHKQ-WLAEVHFLGVVNHPNVVRLLGYCSEDRER--LLVYELMSNRSLE 182
Query 988 DYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L ++ Q L +G+AYLH I+RD + NVLL+ + K+ DFGL
Sbjct 183 DHLFTLRTLTLSWKQRLEIMLGAAQGLAYLHEIQVIYRDFKSSNVLLNEEFHPKLSDFGL 242
Query 1045 AKAVPEGHEYY----RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
A+ PEG + RV DG + APE + DV+SFGV LYE++T
Sbjct 243 AREGPEGDNTHVTTARVGTDG-----YAAPEYVITGHLKTHCDVYSFGVVLYEIIT 293
>sp|B5VNQ3|STE11_YEAS6 Serine/threonine-protein kinase STE11 OS=Saccharomyces
cerevisiae (strain AWRI1631) OX=545124 GN=STE11
PE=3 SV=2
Length=717
Score = 103 bits (257), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 53/153 (35%), Positives = 87/153 (57%), Gaps = 3/153 (2%)
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-F 1003
+ E+++L+ L+HE+I+ Y G ++ G +L + +EYVP GS+ L + L+ F
Sbjct 502 QHEMNLLKELHHENIVTYYGASQEGG--NLNIFLEYVPGGSVSSMLNNYGPFEESLITNF 559
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+QI G+AYLH + IHRD+ N+L+D VKI DFG++K + ++ R
Sbjct 560 TRQILIGVAYLHKKKIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQG 619
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
VFW +PE +K+ +D+WS G + E+ T
Sbjct 620 SVFWMSPEVVKQSATTAKADIWSTGCVVIEMFT 652
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 38/177 (21%), Positives = 77/177 (44%), Gaps = 22/177 (12%)
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
H + A +L+ ++ H ++ +G G + EYV G + L + P
Sbjct 494 HRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLN---NYGP 550
Query 708 MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763
++ +Q+ ++YL K ++H ++ G NIL+ G +K++D G+
Sbjct 551 FEESLITNFTRQILIGVAYLHKKKIIHRDIKGANILIDIKGC-------VKITDFGISKK 603
Query 764 LGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
L L++++ + W++PE + A + D W G ++E+ F G+ P
Sbjct 604 LSPLNKKQNKRASLQGSVFWMSPEVVKQSAT--TAKADIWSTGCVVIEM-FTGKHPF 657
>sp|Q9SII6|PIX13_ARATH Probable serine/threonine-protein kinase
PIX13 OS=Arabidopsis thaliana OX=3702 GN=PIX13 PE=1 SV=2
Length=414
Score = 101 bits (251), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 91/291 (31%), Positives = 133/291 (46%), Gaps = 18/291 (6%)
Query 895 RYLKKIRDLGEGHFGKVS---LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
R + LGEG FGKV L P G ++AVK L A+ Q W+ E++ L
Sbjct 85 RNFRSENVLGEGGFGKVFKGWLEDKTPGKQSNGTVIAVKKLNAESF-QGFEEWQCEVNFL 143
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQ 1006
+ H +++K G C + E L LV EY+ GSL ++L R + L L A
Sbjct 144 GRVSHPNLVKLLGYCLEGEE--LLLVYEYMQKGSLENHLFRKGSAVQPLSWEIRLKIAIG 201
Query 1007 ICEGMAYLHA--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE-YYRVREDGDS 1063
+G+A+LHA + I+RD A N+LLD KI DFGLAK P + + R G
Sbjct 202 AAKGLAFLHASEKQVIYRDFKASNILLDGSYNAKISDFGLAKLGPSASQSHITTRVMGTH 261
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVL 1122
+ APE + Y SDV+ FGV L E+LT + + PT L + ++
Sbjct 262 G--YAAPEYVATGHLYVKSDVYGFGVVLAEILTGLHALDPTRPTGQHNLTEWIKPHLSER 319
Query 1123 R-LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
R L +++ P K V L C E RP+ + ++ L+ +
Sbjct 320 RKLRSIMDPRLEGKYPFKSAFRVAQLALKCLGPEPKNRPSMKEVVESLELI 370
Score = 68.2 bits (165), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 82/314 (26%), Positives = 137/314 (44%), Gaps = 42/314 (13%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
I L+ L TR E L G G +G ++D+ PG+ + + +K L+
Sbjct 74 IFSLAELRASTRNFRSENVLGEGGFGKVFKGWLEDK---TPGKQSNGTV-IAVKKLNAES 129
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV-P 707
+ + + +VSH +L + G C+ G E ++V EY++ G L+ L R+ V P
Sbjct 130 FQGFEEWQCEVNFLGRVSHPNLVKLLGYCLEGEELLLVYEYMQKGSLENHLFRKGSAVQP 189
Query 708 MAW--KMVVAQQLASALSYL--ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
++W ++ +A A L++L K +++ + NILL S K+SD G+
Sbjct 190 LSWEIRLKIAIGAAKGLAFLHASEKQVIYRDFKASNILL-------DGSYNAKISDFGLA 242
Query 764 -LG-ALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGE 812
LG + S+ R+ + APE + G L D +GFG L EI D
Sbjct 243 KLGPSASQSHITTRVMGTHGYAAPEYVATG--HLYVKSDVYGFGVVLAEILTGLHALDPT 300
Query 813 APLQSRSPSE--KEHFYQRQH-----------RLPEPSCPQLATLTSQCLTYEPTQRPSF 859
P + +E K H +R+ + P S ++A L +CL EP RPS
Sbjct 301 RPTGQHNLTEWIKPHLSERRKLRSIMDPRLEGKYPFKSAFRVAQLALKCLGPEPKNRPSM 360
Query 860 RTILRDLTRLQPHN 873
+ ++ L ++ N
Sbjct 361 KEVVESLELIEAAN 374
>sp|Q12852|M3K12_HUMAN Mitogen-activated protein kinase kinase
kinase 12 OS=Homo sapiens OX=9606 GN=MAP3K12 PE=1 SV=2
Length=859
Score = 103 bits (258), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 79/262 (30%), Positives = 116/262 (44%), Gaps = 37/262 (14%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
GE VAVK + R + +I LR L H +II +KG C ++ME+
Sbjct 146 GEEVAVKKV--------RDLKETDIKHLRKLKHPNIITFKGVCTQA--PCYCILMEFCAQ 195
Query 984 GSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
G L + L + + L+ ++ I GM YLH IHRDL + N+L+ D +VKI DF
Sbjct 196 GQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDF 255
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
G +K + + + V W APE ++ D+WSFGV L+ELLT
Sbjct 256 GTSKELSD----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLT-----G 306
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
P K ++ I G + LP P CP L++ CW ++ RP+F
Sbjct 307 EIPYKDVDSSAIIWG---------VGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSF 357
Query 1163 ENLI--------PILKTVHEKY 1176
++ +L T E Y
Sbjct 358 RQILLHLDIASADVLSTPQETY 379
Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 71/260 (27%), Positives = 106/260 (41%), Gaps = 36/260 (14%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
GR G+E+ V KV D DI + ++ H ++ GVC + P ++ E+
Sbjct 142 GRFHGEEV-AVKKVRDLKETDI--------KHLRKLKHPNIITFKGVCTQAPCYCILMEF 192
Query 690 VEHGPLDVWLRRERGHVP---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
G L LR R P + W M +A ++YL ++H ++ N+L+
Sbjct 193 CAQGQLYEVLRAGRPVTPSLLVDWSMGIA----GGMNYLHLHKIIHRDLKSPNMLIT--- 245
Query 747 LAEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+K+SD G + ++ + W+APE + +S +D W FG
Sbjct 246 ----YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 299
Query 804 LLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFR 860
L E+ GE P + S LP PS CP L QC +P RPSFR
Sbjct 300 LWEL-LTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFR 358
Query 861 TILRDLTRLQPHNLADVLTV 880
IL L ADVL+
Sbjct 359 QILLHLDIAS----ADVLST 374
>sp|Q60700|M3K12_MOUSE Mitogen-activated protein kinase kinase
kinase 12 OS=Mus musculus OX=10090 GN=Map3k12 PE=1 SV=1
Length=888
Score = 103 bits (258), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 79/262 (30%), Positives = 116/262 (44%), Gaps = 37/262 (14%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
GE VAVK + R + +I LR L H +II +KG C ++ME+
Sbjct 179 GEEVAVKKV--------RDLKETDIKHLRKLKHPNIITFKGVCTQA--PCYCILMEFCAQ 228
Query 984 GSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
G L + L + + L+ ++ I GM YLH IHRDL + N+L+ D +VKI DF
Sbjct 229 GQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDF 288
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
G +K + + + V W APE ++ D+WSFGV L+ELLT
Sbjct 289 GTSKELSD----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG----- 339
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
P K ++ I G + LP P CP L++ CW ++ RP+F
Sbjct 340 EIPYKDVDSSAIIWG---------VGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSF 390
Query 1163 ENLI--------PILKTVHEKY 1176
++ +L T E Y
Sbjct 391 RQILLHLDIASADVLSTPQETY 412
Score = 63.5 bits (153), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 71/260 (27%), Positives = 106/260 (41%), Gaps = 36/260 (14%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
GR G+E+ V KV D DI + ++ H ++ GVC + P ++ E+
Sbjct 175 GRFHGEEV-AVKKVRDLKETDI--------KHLRKLKHPNIITFKGVCTQAPCYCILMEF 225
Query 690 VEHGPLDVWLRRERGHVP---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
G L LR R P + W M +A ++YL ++H ++ N+L+
Sbjct 226 CAQGQLYEVLRAGRPVTPSLLVDWSMGIA----GGMNYLHLHKIIHRDLKSPNMLIT--- 278
Query 747 LAEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+K+SD G + ++ + W+APE + +S +D W FG
Sbjct 279 ----YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 332
Query 804 LLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFR 860
L E+ GE P + S LP PS CP L QC +P RPSFR
Sbjct 333 LWEL-LTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFR 391
Query 861 TILRDLTRLQPHNLADVLTV 880
IL L ADVL+
Sbjct 392 QILLHLDIAS----ADVLST 407
>sp|P17948|VGFR1_HUMAN Vascular endothelial growth factor receptor
1 OS=Homo sapiens OX=9606 GN=FLT1 PE=1 SV=2
Length=1338
Score = 104 bits (259), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 62/182 (34%), Positives = 96/182 (53%), Gaps = 14/182 (8%)
Query 988 DYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
D + I + L+ ++ Q+ GM +L ++ IHRDLAARN+LL + +VKI DFGLA+
Sbjct 987 DGFYKEPITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLARD 1046
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ + +Y R + D P+ W APE + + + SDVWS+GV L+E+ + S P
Sbjct 1047 IYKNPDYVR-KGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFS-LGGSPYP--- 1101
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
G+ + RL E G R+ P+ E+Y +M +CW + RP F L+
Sbjct 1102 -----GVQMDEDFCSRLRE----GMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVE 1152
Query 1168 IL 1169
L
Sbjct 1153 KL 1154
Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 43/169 (25%), Positives = 72/169 (43%), Gaps = 22/169 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V +
Sbjct 1005 QVARGMEFLSSRKCIHRDLAARNILLSENNV-------VKICDFGLARDIYKNPDYVRKG 1057
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + ST D W +G L EI G +P E F R
Sbjct 1058 DTRLPLKWMAPESIFDKI--YSTKSDVWSYGVLLWEIFSLGGSPYPG--VQMDEDFCSRL 1113
Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
+ R PE S P++ + C +P +RP F ++ L L N+
Sbjct 1114 REGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQANV 1162
Score = 44.3 bits (103), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 45/166 (27%), Positives = 65/166 (39%), Gaps = 17/166 (10%)
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV--NPDSPASDPTV------ 891
+L TLT C+ I R + R D L++ +PD D
Sbjct 758 ELITLTCTCVAATLFWLLLTLFI-RKMKRSSSEIKTDYLSIIMDPDEVPLDEQCERLPYD 816
Query 892 -----FHKRYLKKIRDLGEGHFGK-VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
F + LK + LG G FGK V + T VAVK LK
Sbjct 817 ASKWEFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALM 876
Query 946 QEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
E+ IL + +H +++ G C QG L +++EY G+L +YL
Sbjct 877 TELKILTHIGHHLNVVNLLGACTKQG-GPLMVIVEYCKYGNLSNYL 921
>sp|A7J1T2|M313A_XENLA Mitogen-activated protein kinase kinase
kinase 13-A OS=Xenopus laevis OX=8355 GN=map3k13-a PE=2 SV=1
Length=961
Score = 103 bits (258), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 85/273 (31%), Positives = 122/273 (45%), Gaps = 39/273 (14%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI--LRTL 954
+ +++ LG G G V L + GE VA+K ++ ++E DI LR L
Sbjct 169 ISELQWLGSGAQGAVFLGKF------RGEEVAIKKVRE----------QKETDIKHLRKL 212
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAY 1013
H +II +KG C L+MEY G L + L +LL+ ++ I GM Y
Sbjct 213 KHPNIIAFKGVCTQA--PCYCLIMEYCAHGQLYEVLRAGRKVSPRLLVDWSNGIASGMNY 270
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
LH IHRDL + NVL+ + VKI DFG +K + + + V W APE +
Sbjct 271 LHLHKIIHRDLKSPNVLVTHTDTVKISDFGTSKELSDK----STKMSFAGTVAWMAPEVI 326
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ D+WSFGV L+ELLT P K ++ I G +
Sbjct 327 RNEPVSEKVDIWSFGVLLWELLT-----GEIPYKDVDSSAIIWG---------VGSNSLH 372
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
LP P CP LMK W ++ RP+F ++
Sbjct 373 LPVPSTCPDGFKILMKQTWHSKPRNRPSFRQIL 405
Score = 66.2 bits (160), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 77/308 (25%), Positives = 123/308 (40%), Gaps = 54/308 (18%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+A L Q V +EI++L LG G + V+ G+ R
Sbjct 147 GKAYSTDYKLQQQETWEVPFEEISELQWLGSGAQGAVFLGKFR----------------- 189
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
G+E+ + KV + DI + ++ H ++ GVC + P ++
Sbjct 190 -------GEEV-AIKKVREQKETDIKH--------LRKLKHPNIIAFKGVCTQAPCYCLI 233
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLAR 744
EY HG L LR R P +++V + +AS ++YL ++H ++ N+L+
Sbjct 234 MEYCAHGQLYEVLRAGRKVSP---RLLVDWSNGIASGMNYLHLHKIIHRDLKSPNVLVTH 290
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFG 801
+ +K+SD G + ++ + W+APE + +S +D W FG
Sbjct 291 -------TDTVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFG 341
Query 802 ATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPS 858
L E+ GE P + S LP PS CP L Q +P RPS
Sbjct 342 VLLWEL-LTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWHSKPRNRPS 400
Query 859 FRTILRDL 866
FR IL L
Sbjct 401 FRQILMHL 408
>sp|P00531|MIL_AVIMH Serine/threonine-protein kinase-transforming
protein mil OS=Avian retrovirus MH2 OX=11870 GN=V-MIL PE=3
SV=1
Length=380
Score = 100 bits (249), Expect = 4e-21, Method: Compositional matrix adjust.
Identities = 68/200 (34%), Positives = 102/200 (51%), Gaps = 17/200 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+
Sbjct 88 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILL 140
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++
Sbjct 141 FMGYMT---KDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 197
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076
IHRD+ + N+ L VKIGDFGLA +V + S + W APE ++
Sbjct 198 IHRDMKSNNIFLHGGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-ILWMAPEVIRMQDSN 256
Query 1077 KFYYASDVWSFGVTLYELLT 1096
F + SDV+S+G+ LYEL+T
Sbjct 257 PFSFQSDVYSYGIVLYELMT 276
Score = 64.7 bits (156), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 72/286 (25%), Positives = 126/286 (44%), Gaps = 32/286 (11%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688
G+ G +LKV+DP+ AF +++ + H ++ G + +N+ +VT+
Sbjct 99 GKWHGDVAVKILKVVDPTPEQFQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 155
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ E L L + M + +A+Q A + YL KN++H ++ NI L GL
Sbjct 156 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFL-HGGLT 214
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFG 801
+K+ D G+ G+ E+ I W+APE + +N S D + +G
Sbjct 215 ------VKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYG 268
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854
L E+ GE P + ++ F R + P+ S CP+ + L + CL
Sbjct 269 IVLYEL-MTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVRE 327
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+RP F IL + LQ H+L + + AS+P++ + + I
Sbjct 328 ERPLFPQILSSIALLQ-HSLPKI-----NRSASEPSLHRASHTEDI 367
>sp|Q8GXZ3|PBL8_ARATH Probable serine/threonine-protein kinase
PBL8 OS=Arabidopsis thaliana OX=3702 GN=PBL8 PE=1 SV=1
Length=410
Score = 100 bits (249), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 81/230 (35%), Positives = 118/230 (51%), Gaps = 14/230 (6%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LGEG FG V Y D G + VAVK L + HR W E++ L L H +++
Sbjct 75 LGEGGFGTVYKGYIDDNLRVGLKSLPVAVKVLNKEGLQGHRE-WLTEVNFLGQLRHPNLV 133
Query 961 KYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA 1016
K G CCED LV E++ GSL ++L R + + ++ ++ A +G+A+LH
Sbjct 134 KLIGYCCEDDHR---LLVYEFMLRGSLENHLFRKTTAPLSWSRRMMIALGAAKGLAFLHN 190
Query 1017 QH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
I+RD N+LLD+D K+ DFGLAKA P+G E + V + APE +
Sbjct 191 AERPVIYRDFKTSNILLDSDYTAKLSDFGLAKAGPQGDETH-VSTRVMGTYGYAAPEYVM 249
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR 1123
SDV+SFGV L E+LT S ++ P+K L+ A+ ++ R
Sbjct 250 TGHLTARSDVYSFGVVLLEMLTGRKSVDKTRPSKEQNLVDWARPKLNDKR 299
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 60/265 (23%), Positives = 109/265 (41%), Gaps = 40/265 (15%)
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+ L V +KVL+ + + + Q+ H +L + G C ++V E++ G
Sbjct 97 KSLPVAVKVLNKEGLQGHREWLTEVNFLGQLRHPNLVKLIGYCCEDDHRLLVYEFMLRGS 156
Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGLAEG 750
L+ L R + P++W +M++A A L++L N + +++ + NILL
Sbjct 157 LENHLFR-KTTAPLSWSRRMMIALGAAKGLAFLHNAERPVIYRDFKTSNILL-------D 208
Query 751 TSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+ KLSD G+ +E + + APE + G L+ D + FG L
Sbjct 209 SDYTAKLSDFGLAKAGPQGDETHVSTRVMGTYGYAAPEYVMTG--HLTARSDVYSFGVVL 266
Query 805 LEICFDGEAPLQSRSPSEKEHFY-------QRQHRLPEPSCPQL------------ATLT 845
LE+ G + PS++++ + +L + P+L +L
Sbjct 267 LEM-LTGRKSVDKTRPSKEQNLVDWARPKLNDKRKLLQIIDPRLENQYSVRAAQKACSLA 325
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQ 870
CL+ P RP ++ L LQ
Sbjct 326 YYCLSQNPKARPLMSDVVETLEPLQ 350
>sp|P11346|KRAF1_DROME Raf homolog serine/threonine-protein kinase
Raf OS=Drosophila melanogaster OX=7227 GN=Raf PE=1 SV=6
Length=739
Score = 103 bits (256), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 81/277 (29%), Positives = 127/277 (46%), Gaps = 29/277 (10%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHII 960
+G G FG V + + P VAVK L P +K E+ +L+ H +I+
Sbjct 435 IGSGSFGTVYRAHWHGP--------VAVKTLNVKTPSPAQLQAFKNEVAMLKKTRHCNIL 486
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ GC + SL +V ++ SL ++ L L+ +Q+ +GM YLHA++
Sbjct 487 LFMGCV---SKPSLAIVTQWCEGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYLHAKN 543
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK- 1077
IHRDL + N+ L D VKIGDFGLA A + + S + W APE ++ +
Sbjct 544 IIHRDLKSNNIFLHEDLSVKIGDFGLATAKTRWSGEKQANQPTGS-ILWMAPEVIRMQEL 602
Query 1078 --FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ + SDV++FG+ +YELL C K L + +G LL
Sbjct 603 NPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRG---------LLRPDMSQV 653
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
R D P + L ++C + RP F L+ +L+ +
Sbjct 654 RSD-APQALKRLAEDCIKYTPKDRPLFRPLLNMLENM 689
Score = 54.3 bits (129), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 58/245 (24%), Positives = 97/245 (40%), Gaps = 26/245 (11%)
Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
L V PS + AF +++ + H ++ G CV P +VT++ E L +
Sbjct 456 TLNVKTPSPAQLQ-AFKNEVAMLKKTRHCNILLFMG-CVSKPSLAIVTQWCEGSSLYKHV 513
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ + + +Q+A + YL KN++H ++ NI L E S +K+ D
Sbjct 514 HVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSNNIF-----LHEDLS--VKIGD 566
Query 760 PGVGLGAL--SREERVER----IPWLAPECLPGGA-NSLSTAMDKWGFGATLLEICFDGE 812
G+ S E++ + I W+APE + N S D + FG + E+ E
Sbjct 567 FGLATAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELL--AE 624
Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQ--------LATLTSQCLTYEPTQRPSFRTILR 864
++ + + L P Q L L C+ Y P RP FR +L
Sbjct 625 CLPYGHISNKDQILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLN 684
Query 865 DLTRL 869
L +
Sbjct 685 MLENM 689
>sp|O22040|ANP1_ARATH Mitogen-activated protein kinase kinase
kinase ANP1 OS=Arabidopsis thaliana OX=3702 GN=ANP1 PE=1 SV=2
Length=666
Score = 102 bits (255), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 70/274 (26%), Positives = 125/274 (46%), Gaps = 32/274 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-------KADCGPQHRSGWKQEIDILRTLY 955
+G G FG V Y N +GE++AVK + + H ++E+ +L+ L
Sbjct 75 IGRGAFGTV----YMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLS 130
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYL 1014
H +I++Y G + + +L +++E+VP GS+ L + + + + +Q+ G+ YL
Sbjct 131 HPNIVRYLGTVRE--DDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYL 188
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H +HRD+ N+L+DN +K+ DFG +K V E + +P +W APE +
Sbjct 189 HNHAIMHRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTP-YWMAPEVIL 247
Query 1075 EYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ +++D+WS G T+ E++T S Q + IG +
Sbjct 248 QTGHSFSADIWSVGCTVIEMVTGKAPWSQQYKEVAAIFFIGTTKSHP------------- 294
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
P PD + + C + + RPT L+
Sbjct 295 --PIPDTLSSDAKDFLLKCLQEVPNLRPTASELL 326
Score = 53.1 bits (126), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 52/218 (24%), Positives = 90/218 (41%), Gaps = 21/218 (10%)
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
E L+ +SH ++ G ++ E+V G + L + G P + +
Sbjct 121 EEVKLLKNLSHPNIVRYLGTVREDDTLNILLEFVPGGSISSLLEK-FGPFPESVVRTYTR 179
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-----LGALSREE 771
QL L YL N ++H ++ G NIL+ G IKL+D G L ++ +
Sbjct 180 QLLLGLEYLHNHAIMHRDIKGANILVDNKGC-------IKLADFGASKQVAELATMTGAK 232
Query 772 RVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
++ P W+APE + +S S D W G T++E+ G+AP + F+
Sbjct 233 SMKGTPYWMAPEVILQTGHSFSA--DIWSVGCTVIEMVT-GKAPWSQQYKEVAAIFFIGT 289
Query 831 HR----LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ +P+ +CL P RP+ +L+
Sbjct 290 TKSHPPIPDTLSSDAKDFLLKCLQEVPNLRPTASELLK 327
>sp|Q7T6Y2|YR831_MIMIV Putative serine/threonine-protein kinase/receptor
R831 OS=Acanthamoeba polyphaga mimivirus OX=212035
GN=MIMI_R831 PE=3 SV=2
Length=1624
Score = 103 bits (258), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 85/279 (30%), Positives = 134/279 (48%), Gaps = 31/279 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G +G+V Y GT V + + K RS + +E+ I+ +L H +++ +
Sbjct 792 LGTGGYGEV----YKSIWKGTEVAVKLISSKHVSKDMERSFF-EEVKIMTSLRHPNVVLF 846
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQHY 1019
++ +VME++ LGSL D L I A + A Q +GM +LH+
Sbjct 847 MAAS--TKSPNMCIVMEFMSLGSLYDLLGNELIPEIPYALKIKMAYQASKGMHFLHSSGI 904
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK-- 1077
+HRDL + N+LLD+ VK+ DFGL K E + + ++ + W APE L +
Sbjct 905 VHRDLKSLNLLLDSKWNVKVSDFGLTKVKSE-LDKKKTNDNIIGTIHWIAPEILNDSTEV 963
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
Y +DV+SFG+ L+ELLT + P K + IA ++V+R G R P
Sbjct 964 DYILADVYSFGIILWELLT-----REQPYKGMTPAAIA---VSVIR------DGMRPPIS 1009
Query 1138 DKC----PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
D+ E L+K CW ++ RPTF ++ L +
Sbjct 1010 DEAVTAHSIEYIDLIKQCWHSDTIIRPTFLEIMTRLSNI 1048
Score = 100 bits (249), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 80/264 (30%), Positives = 124/264 (47%), Gaps = 37/264 (14%)
Query 924 GEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982
G VAVK +K ++ E+ L L H +I+ + G C + ++ +V EY+
Sbjct 1385 GVDVAVKKFVKQKLSETQLLEFRAEMAFLSELKHSNIVTFIGACIKK--PNICIVTEYMR 1442
Query 983 LGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDNDRLVK 1038
+G+LRD L P I A L G+ YLH+ + +HRD+ N+L+D VK
Sbjct 1443 MGNLRDVLKNPDIKITFANKLKLLYGAAMGIDYLHSSNPMIVHRDIKPANILVDEHFNVK 1502
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPV-----FWYAPECLKEYKFYYASDVWSFGVTLYE 1093
I DFG A R++ED + W APE ++ K+ +DV+SFGV ++E
Sbjct 1503 IADFGFA----------RIKEDNTTMTRCGTPCWTAPEVIRGEKYCEKADVFSFGVVMWE 1552
Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
+LT + P A+ + L ++LE G R P CP E L+K CW
Sbjct 1553 VLT----GKEP---------FAECNFMKVSL-DILEGG-RPIIPSDCPHEFAKLIKKCWH 1597
Query 1154 TEASFRPTFENLIPILKTVHEKYQ 1177
+A RPT ++ L + E++
Sbjct 1598 AKAHKRPTMTEVVQQLMLITEQFD 1621
Score = 58.5 bits (140), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 56/251 (22%), Positives = 100/251 (40%), Gaps = 22/251 (9%)
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
+G E+ V L D+ +F+E +M+ + H ++ + P +V E++
Sbjct 806 KGTEVAVKLISSKHVSKDMERSFFEEVKIMTSLRHPNVVLFMAASTKSPNMCIVMEFMSL 865
Query 693 GPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G L L E +P A K+ +A Q + + +L + +VH ++ N+LL +
Sbjct 866 GSLYDLLGNELIPEIPYALKIKMAYQASKGMHFLHSSGIVHRDLKSLNLLL-------DS 918
Query 752 SPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+K+SD G+ + + + I W+APE L D + FG L
Sbjct 919 KWNVKVSDFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSFGIILW 978
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------CPQLATLTSQCLTYEPTQRPS 858
E+ E P + +P+ R P S + L QC + RP+
Sbjct 979 EL-LTREQPYKGMTPAAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQCWHSDTIIRPT 1037
Query 859 FRTILRDLTRL 869
F I+ L+ +
Sbjct 1038 FLEIMTRLSNI 1048
Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 50/225 (22%), Positives = 93/225 (41%), Gaps = 26/225 (12%)
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
L F + +S++ H+++ G C++ P +VTEY+ G L L+ + A K+
Sbjct 1404 LEFRAEMAFLSELKHSNIVTFIGACIKKPNICIVTEYMRMGNLRDVLKNPDIKITFANKL 1463
Query 713 VVAQQLASALSYLENKN--LVHGNVCGRNILLAR-LGLAEGTSPFIKLSDPGVGLGALSR 769
+ A + YL + N +VH ++ NIL+ + F ++ + +
Sbjct 1464 KLLYGAAMGIDYLHSSNPMIVHRDIKPANILVDEHFNVKIADFGFARIKEDNTTM----- 1518
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
R W APE + G D + FG + E+ L + P + +F +
Sbjct 1519 -TRCGTPCWTAPEVIRG--EKYCEKADVFSFGVVMWEV-------LTGKEPFAECNFMKV 1568
Query 830 QHRLPE------PS-CP-QLATLTSQCLTYEPTQRPSFRTILRDL 866
+ E PS CP + A L +C + +RP+ +++ L
Sbjct 1569 SLDILEGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTMTEVVQQL 1613
>sp|A7J1T0|M313B_XENLA Mitogen-activated protein kinase kinase
kinase 13-B OS=Xenopus laevis OX=8355 GN=map3k13-b PE=2 SV=1
Length=961
Score = 103 bits (256), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 84/273 (31%), Positives = 123/273 (45%), Gaps = 39/273 (14%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI--LRTL 954
+ +++ LG G G V L + GE VA+K ++ ++E DI LR L
Sbjct 171 ISELQWLGSGAQGAVFLGKF------RGEEVAIKKVRE----------QKETDIKHLRKL 214
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAY 1013
H +II +KG C ++MEY G L + L +LL+ ++ I GM Y
Sbjct 215 KHPNIIAFKGVCTQA--PCYCILMEYCAQGQLYEVLRAGRKVTPKLLVEWSTGIASGMNY 272
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
LH IHRDL + NVL+ + VKI DFG +K + + + V W APE +
Sbjct 273 LHLHKIIHRDLKSPNVLVTHADTVKISDFGTSKELSD----KSTKMSFAGTVAWMAPEVI 328
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ D+WSFGV L+ELLT P K ++ I G +
Sbjct 329 RNEPVSEKVDIWSFGVLLWELLT-----GEIPYKDVDSSAIIWG---------VGSNSLH 374
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
LP P CP LMK W+++ RP+F ++
Sbjct 375 LPVPSTCPDGFKILMKQTWQSKPRNRPSFRQIL 407
Score = 63.5 bits (153), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 77/308 (25%), Positives = 121/308 (39%), Gaps = 54/308 (18%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+A L Q V +EI++L LG G + V+ G+ R
Sbjct 149 GKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFR----------------- 191
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
G+E+ + KV + DI + ++ H ++ GVC + P ++
Sbjct 192 -------GEEV-AIKKVREQKETDIKH--------LRKLKHPNIIAFKGVCTQAPCYCIL 235
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLAR 744
EY G L LR R P K++V + +AS ++YL ++H ++ N+L+
Sbjct 236 MEYCAQGQLYEVLRAGRKVTP---KLLVEWSTGIASGMNYLHLHKIIHRDLKSPNVLVTH 292
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFG 801
+K+SD G + ++ + W+APE + +S +D W FG
Sbjct 293 ADT-------VKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFG 343
Query 802 ATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPS 858
L E+ GE P + S LP PS CP L Q +P RPS
Sbjct 344 VLLWEL-LTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPS 402
Query 859 FRTILRDL 866
FR IL L
Sbjct 403 FRQILMHL 410
>sp|P27966|RMIL_AVEVR Serine/threonine-protein kinase-transforming
protein Rmil OS=Avian rous-associated virus type 1 OX=11950
GN=V-RMIL PE=3 SV=1
Length=450
Score = 100 bits (250), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 79/277 (29%), Positives = 123/277 (44%), Gaps = 41/277 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK L PQ +K E+ +LR H +I+
Sbjct 89 IGSGSFGTV----YKGKWHGD---VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 141
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + L +V ++ SL +L + +L+ A+Q +GM YLHA+
Sbjct 142 FMGYST---KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSI 198
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPE---GHEYYRVREDGDSPVFWYAPECLK-- 1074
IHRDL + N+ L D VKIGDFGLA H++ E + W APE ++
Sbjct 199 IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQF----EQLSGSILWMAPEVIRMQ 254
Query 1075 -EYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
+ + + SDV++FG+ LYEL+T + + + F+ G ++ +R
Sbjct 255 DKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVR------ 308
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
CP + LM C + + RP F ++
Sbjct 309 --------SNCPKAMKRLMAECLKKKRDERPLFPQIL 337
Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 58/244 (24%), Positives = 103/244 (42%), Gaps = 24/244 (10%)
Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+L V P+ + AF ++ + H ++ G + P+ +VT++ E L L
Sbjct 110 MLNVTAPTPQQLQ-AFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHL 167
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
M + +A+Q A + YL K+++H ++ NI L +K+ D
Sbjct 168 HIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE-------DLTVKIGD 220
Query 760 PGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGATLLEICFDGE 812
G+ G+ E+ I W+APE + N S D + FG L E+ G+
Sbjct 221 FGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYEL-MTGQ 279
Query 813 APLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQRPSFRTILRD 865
P + + ++ F R + P+ S CP+ + L ++CL + +RP F IL
Sbjct 280 LPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILAS 339
Query 866 LTRL 869
+ L
Sbjct 340 IELL 343
>sp|G4NDR3|MCK1_PYRO7 Mitogen-activated protein kinase kinae kinase
MCK1 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617
/ FGSC 8958) OX=242507 GN=MCK1 PE=1 SV=1
Length=1528
Score = 103 bits (257), Expect = 7e-21, Method: Compositional matrix adjust.
Identities = 86/297 (29%), Positives = 143/297 (48%), Gaps = 47/297 (16%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL----KADCGPQHR--- 941
PT F R+ K + +G+G +G+V L N TGE +AVK + +A G + R
Sbjct 1233 PTTF--RWFKG-QLIGKGTYGRVYLGM----NATTGEFLAVKEVEVNPRAAAGDKKRMKE 1285
Query 942 --SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLA 998
+ QEI+ ++ L H +I++Y GC ++ E S+ + +EY+ GS+ L ++ +
Sbjct 1286 LVAALDQEIETMQHLDHVNIVQYLGC--ERKETSISIFLEYISGGSIGSCLRKNGKFEES 1343
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE--GHEYYR 1056
+ +Q G+AYLH + +HRDL A N+LLD D KI DFG++K G++
Sbjct 1344 VVQSLTRQTLSGLAYLHREGILHRDLKADNILLDVDGTAKISDFGISKKTDNIYGNDKSN 1403
Query 1057 VREDGDSPVFWYAPECLKEYKFYYAS--DVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ VFW APE ++ Y++ D+WS G + E+ + + P K + I
Sbjct 1404 SMQGS---VFWMAPEVIRSQGEGYSAKVDIWSLGCVVLEMF----AGRRPWAKEEAVGAI 1456
Query 1115 AQGQMTVLRLTELLERGERLPRPDK-----CPCEVYHLMKNCWETEASFRPTFENLI 1166
+ + GE P P+ P V +M +C+ ++ RPT L+
Sbjct 1457 YK-----------IANGEIPPIPEDVQDTISPIAVAFMM-DCFTVDSHDRPTANKLL 1501
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 43/172 (25%), Positives = 71/172 (41%), Gaps = 17/172 (10%)
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV-TEYVEHGPLDVWLRRERGHVPM 708
++ A + M + H ++ G C R +I + EY+ G + LR+ G
Sbjct 1285 ELVAALDQEIETMQHLDHVNIVQYLG-CERKETSISIFLEYISGGSIGSCLRKN-GKFEE 1342
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----- 763
+ + +Q S L+YL + ++H ++ NILL G A K+SD G+
Sbjct 1343 SVVQSLTRQTLSGLAYLHREGILHRDLKADNILLDVDGTA-------KISDFGISKKTDN 1395
Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G + W+APE + S +D W G +LE+ F G P
Sbjct 1396 IYGNDKSNSMQGSVFWMAPEVIRSQGEGYSAKVDIWSLGCVVLEM-FAGRRP 1446
>sp|O49840|PBL3_ARATH Probable serine/threonine-protein kinase
PBL3 OS=Arabidopsis thaliana OX=3702 GN=PBL3 PE=1 SV=1
Length=426
Score = 100 bits (249), Expect = 7e-21, Method: Compositional matrix adjust.
Identities = 79/207 (38%), Positives = 109/207 (53%), Gaps = 20/207 (10%)
Query 903 LGEGHFGKVSLYCYDPTN-----DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LGEG FG V D T G+G +VAVK LK + G Q W E++ L L H
Sbjct 89 LGEGGFGYVFKGWIDGTTLTASKPGSGIVVAVKKLKTE-GYQGHKEWLTEVNYLGQLSHP 147
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI------CEGM 1011
+++K G C +GE L LV E++P GSL ++L R AQ L +A ++ +G+
Sbjct 148 NLVKLVGYCV-EGENRL-LVYEFMPKGSLENHLFRRG---AQPLTWAIRMKVAIGAAKGL 202
Query 1012 AYLH--AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+LH I+RD A N+LLD + K+ DFGLAKA P G + + V + A
Sbjct 203 TFLHDAKSQVIYRDFKAANILLDAEFNSKLSDFGLAKAGPTGDKTH-VSTQVMGTHGYAA 261
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096
PE + + SDV+SFGV L ELL+
Sbjct 262 PEYVATGRLTAKSDVYSFGVVLLELLS 288
Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 68/265 (26%), Positives = 111/265 (42%), Gaps = 38/265 (14%)
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
G + V +K L + + + + Q+SH +L + G CV G ++V E++ G
Sbjct 113 GSGIVVAVKKLKTEGYQGHKEWLTEVNYLGQLSHPNLVKLVGYCVEGENRLLVYEFMPKG 172
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGLAE 749
L+ L R RG P+ W +M VA A L++L + +++ + NILL AE
Sbjct 173 SLENHLFR-RGAQPLTWAIRMKVAIGAAKGLTFLHDAKSQVIYRDFKAANILLD----AE 227
Query 750 GTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
S KLSD G+ + ++ + + APE + G L+ D + FG
Sbjct 228 FNS---KLSDFGLAKAGPTGDKTHVSTQVMGTHGYAAPEYVATG--RLTAKSDVYSFGVV 282
Query 804 LLEICFDGEAPLQSRSPSE--------------KEHFYQRQHRL----PEPSCPQLATLT 845
LLE+ A +S+ E ++ F RL P+ A+L
Sbjct 283 LLELLSGRRAVDKSKVGMEQSLVDWATPYLGDKRKLFRIMDTRLGGQYPQKGAYTAASLA 342
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQ 870
QCL + RP +L L +L+
Sbjct 343 LQCLNPDAKLRPKMSEVLAKLDQLE 367
>sp|Q06548|PBL9_ARATH Probable serine/threonine-protein kinase
PBL9 OS=Arabidopsis thaliana OX=3702 GN=PBL9 PE=1 SV=1
Length=410
Score = 100 bits (248), Expect = 7e-21, Method: Compositional matrix adjust.
Identities = 92/290 (32%), Positives = 136/290 (47%), Gaps = 28/290 (10%)
Query 903 LGEGHFGKV--------SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
LGEG FG V SL P GTG ++AVK L D G Q W E++ L
Sbjct 74 LGEGGFGCVFKGWIDEKSLTASRP---GTGLVIAVKKLNQD-GWQGHQEWLAEVNYLGQF 129
Query 955 YHEHIIKYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQIC 1008
H H++K G C ED+ LV E++P GSL ++L R + L L A
Sbjct 130 SHRHLVKLIGYCLEDEHR---LLVYEFMPRGSLENHLFRRGLYFQPLSWKLRLKVALGAA 186
Query 1009 EGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE-YYRVREDGDSPV 1065
+G+A+LH+ I+RD N+LLD++ K+ DFGLAK P G + + R G
Sbjct 187 KGLAFLHSSETRVIYRDFKTSNILLDSEYNAKLSDFGLAKDGPIGDKSHVSTRVMGTHG- 245
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR- 1123
+ APE L SDV+SFGV L ELL+ + ++ P+ L+ A+ + R
Sbjct 246 -YAAPEYLATGHLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRK 304
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ +++ + + C+V L C TE RP ++ L+ +
Sbjct 305 IFRVIDNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVVSHLEHIQ 354
Score = 60.5 bits (145), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 90/348 (26%), Positives = 144/348 (41%), Gaps = 66/348 (19%)
Query 568 RASPRTL-------NLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618
R SPRT NL SF + + S LG+G V++G +
Sbjct 38 RPSPRTEGEILQSPNLKSFSFAELKSATRNFRPDSVLGEGGFGCVFKGWI---------- 87
Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678
DE L R G L + +K L+ + + + Q SH HL + G C+
Sbjct 88 ----DEKSLTASRP-GTGLVIAVKKLNQDGWQGHQEWLAEVNYLGQFSHRHLVKLIGYCL 142
Query 679 RGPENIMVTEYVEHGPLDVWL-RRERGHVPMAWK--MVVAQQLASALSYLENKN--LVHG 733
++V E++ G L+ L RR P++WK + VA A L++L + +++
Sbjct 143 EDEHRLLVYEFMPRGSLENHLFRRGLYFQPLSWKLRLKVALGAAKGLAFLHSSETRVIYR 202
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVE-RI----PWLAPECLPGG 787
+ NILL + KLSD G+ G + + V R+ + APE L G
Sbjct 203 DFKTSNILL-------DSEYNAKLSDFGLAKDGPIGDKSHVSTRVMGTHGYAAPEYLATG 255
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--------------------EHFY 827
L+T D + FG LLE+ A ++R E+ ++
Sbjct 256 --HLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRKIFRVIDNRL 313
Query 828 QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
Q Q+ + E +C ++ATL+ +CLT E RP+ ++ L +Q N A
Sbjct 314 QDQYSM-EEAC-KVATLSLRCLTTEIKLRPNMSEVVSHLEHIQSLNAA 359
>sp|Q54TA3|MRKC_DICDI Probable serine/threonine-protein kinase
MARK-C OS=Dictyostelium discoideum OX=44689 GN=mrkC PE=3 SV=1
Length=773
Score = 102 bits (254), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 71/200 (36%), Positives = 107/200 (54%), Gaps = 14/200 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEH 958
+ LG G FGKV L TN T E VA+K +K + G Q + ++ EIDI++ L H +
Sbjct 50 KTLGNGTFGKVKL----GTNICTKENVAIKFIKNNKLSGKQKETCFR-EIDIMKLLDHPN 104
Query 959 IIKYKGCCEDQGEK-SLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHA 1016
I+K + + E+ + L++EYV G L DY+ R I + F +Q+ + Y HA
Sbjct 105 IVKLLDVVDKREEEGTTYLIVEYVSGGELFDYIVAREYIKEKEARKFFRQMISAIEYCHA 164
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL N+LLD++ +KI DFGL+ + G ++ E + APE LK
Sbjct 165 NLIVHRDLKPENLLLDSNGDIKISDFGLSNNIQPG----KLLESFCGSPLYAAPEILKAE 220
Query 1077 KFYY-ASDVWSFGVTLYELL 1095
K+ D+WS GV +Y +L
Sbjct 221 KYLGPPVDIWSLGVIMYAVL 240
>sp|Q9C9U5|SIS8_ARATH Probable serine/threonine-protein kinase
SIS8 OS=Arabidopsis thaliana OX=3702 GN=SIS8 PE=1 SV=1
Length=1030
Score = 102 bits (255), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 81/283 (29%), Positives = 131/283 (46%), Gaps = 34/283 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G +G+V D G VAVK L D + ++ E+ I++ L H +I+
Sbjct 754 IGLGSYGEVY------RGDWHGTEVAVKKFLDQDLTGEALEEFRSEVRIMKKLRHPNIVL 807
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018
+ G +L +V E++P GSL + P + + + L A GM YLH+ +
Sbjct 808 FMGAV--TRPPNLSIVTEFLPRGSLYRLIHRPNNQLDERRRLRMALDAARGMNYLHSCNP 865
Query 1019 -YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL + N+L+D + +VK+ DFGL++ H Y + W APE L+
Sbjct 866 MIVHRDLKSPNLLVDKNWVVKVCDFGLSRM---KHSTYLSSKSTAGTAEWMAPEVLRNEP 922
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKF--LELIGIAQGQMTVLRLTELLERGERLP 1135
DV+S+GV L+EL T Q P K ++++G Q RL
Sbjct 923 ADEKCDVYSYGVILWELFTL----QQPWGKMNPMQVVGAVGFQH------------RRLD 966
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
PD + L+ CW+T++ RP+F ++ LK + + G
Sbjct 967 IPDFVDPAIADLISKCWQTDSKLRPSFAEIMASLKRLQKPVTG 1009
Score = 60.8 bits (146), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 62/242 (26%), Positives = 102/242 (42%), Gaps = 20/242 (8%)
Query 639 VVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V K LD AL F +M ++ H ++ G R P +VTE++ G L
Sbjct 773 AVKKFLDQDLTGEALEEFRSEVRIMKKLRHPNIVLFMGAVTRPPNLSIVTEFLPRGSLYR 832
Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFI 755
+ R + ++ +A A ++YL + N +VH ++ N+L+ + + +
Sbjct 833 LIHRPNNQLDERRRLRMALDAARGMNYLHSCNPMIVHRDLKSPNLLVDK-------NWVV 885
Query 756 KLSDPGVGLGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
K+ D G+ LS + W+APE L D + +G L E+ F
Sbjct 886 KVCDFGLSRMKHSTYLSSKSTAGTAEWMAPEVLRN--EPADEKCDVYSYGVILWEL-FTL 942
Query 812 EAPLQSRSPSEKEHFYQRQHR---LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ P +P + QHR +P+ P +A L S+C + RPSF I+ L R
Sbjct 943 QQPWGKMNPMQVVGAVGFQHRRLDIPDFVDPAIADLISKCWQTDSKLRPSFAEIMASLKR 1002
Query 869 LQ 870
LQ
Sbjct 1003 LQ 1004
>sp|F4J0D2|PBL36_ARATH Serine/threonine-protein kinase PBL36 OS=Arabidopsis
thaliana OX=3702 GN=PBL36 PE=1 SV=2
Length=476
Score = 100 bits (250), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 75/205 (37%), Positives = 104/205 (51%), Gaps = 16/205 (8%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LGEG FG V + P GTG VAVK L D G Q W EI+ L L H
Sbjct 132 LGEGGFGCVFKGWIEENGTAPVKPGTGLTVAVKTLNPD-GLQGHKEWLAEINFLGNLVHP 190
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLH 1015
++K G C ++ ++ LV E++P GSL ++L R ++ L + + A +G+A+LH
Sbjct 191 SLVKLVGYCMEEDQR--LLVYEFMPRGSLENHLFRRTLPLPWSVRMKIALGAAKGLAFLH 248
Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPE 1071
+ I+RD N+LLD + K+ DFGLAK P E + R G + APE
Sbjct 249 EEAEKPVIYRDFKTSNILLDGEYNAKLSDFGLAKDAPDEKKSHVSTRVMGT--YGYAAPE 306
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
+ SDV+SFGV L E+LT
Sbjct 307 YVMTGHLTTKSDVYSFGVVLLEILT 331
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 78/313 (25%), Positives = 127/313 (41%), Gaps = 57/313 (18%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
S LG+G V++G + G+ P+ PG L V +K L+P
Sbjct 130 SLLGEGGFGCVFKGWIEENGTA-----------PVKPGTG----LTVAVKTLNPDGLQGH 174
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
+ + + + H L + G C+ + ++V E++ G L+ L R +P + +M
Sbjct 175 KEWLAEINFLGNLVHPSLVKLVGYCMEEDQRLLVYEFMPRGSLENHLFRRTLPLPWSVRM 234
Query 713 VVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+A A L++L K +++ + NILL A KLSD GL +
Sbjct 235 KIALGAAKGLAFLHEEAEKPVIYRDFKTSNILLDGEYNA-------KLSD--FGLAKDAP 285
Query 770 EERVERIP--------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+E+ + + APE + G L+T D + FG LLEI + +SR
Sbjct 286 DEKKSHVSTRVMGTYGYAAPEYVMTG--HLTTKSDVYSFGVVLLEILTGRRSVDKSRPNG 343
Query 822 EKE-------HFY--QRQHRLPEPSC--------PQLAT-LTSQCLTYEPTQRPSFRTIL 863
E+ H +R +RL +P Q AT + +QCL + RP ++
Sbjct 344 EQNLVEWVRPHLLDKKRFYRLLDPRLEGHYSIKGAQKATQVAAQCLNRDSKARPKMSEVV 403
Query 864 RDLTRLQPHNLAD 876
L L NL D
Sbjct 404 EALKPLP--NLKD 414
>sp|Q9LPQ3|M2K7_ARATH Mitogen-activated protein kinase kinase
7 OS=Arabidopsis thaliana OX=3702 GN=MKK7 PE=1 SV=1
Length=307
Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 62/204 (30%), Positives = 104/204 (51%), Gaps = 13/204 (6%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
++K+ LG G G V Y + TGE+ A+K++ D P +E++ILR
Sbjct 45 VEKLHVLGRGSSGIV----YKVHHKTTGEIYALKSVNGDMSPAFTRQLAREMEILRRTDS 100
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016
++++ +G E + ++MEY+ G+L R ++ QL F++QI +G++YLH+
Sbjct 101 PYVVRCQGIFEKPIVGEVSILMEYMDGGNLESL--RGAVTEKQLAGFSRQILKGLSYLHS 158
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE----C 1072
+HRD+ N+LL++ VKI DFG++K + +Y + +PE
Sbjct 159 LKIVHRDIKPANLLLNSRNEVKIADFGVSKIITRSLDYC---NSYVGTCAYMSPERFDSA 215
Query 1073 LKEYKFYYASDVWSFGVTLYELLT 1096
E YA D+WSFGV + EL
Sbjct 216 AGENSDVYAGDIWSFGVMILELFV 239
Score = 42.0 bits (97), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 47/186 (25%), Positives = 75/186 (40%), Gaps = 28/186 (15%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL-- 742
++ EY++ G L+ RG V ++Q+ LSYL + +VH ++ N+LL
Sbjct 120 ILMEYMDGGNLESL----RGAVTEKQLAGFSRQILKGLSYLHSLKIVHRDIKPANLLLNS 175
Query 743 ------ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMD 796
A G+++ + + + VG A ER + G NS A D
Sbjct 176 RNEVKIADFGVSKIITRSLDYCNSYVGTCAYMSPERFDS---------AAGENSDVYAGD 226
Query 797 KWGFGATLLEICFDGEAPL--QSRSPSEKEHF----YQRQHRLPEPSCPQLATLTSQCLT 850
W FG +LE+ F G PL Q + P + R PE + + CL
Sbjct 227 IWSFGVMILEL-FVGHFPLLPQGQRPDWATLMCVVCFGEPPRAPEGCSDEFRSFVDCCLR 285
Query 851 YEPTQR 856
E ++R
Sbjct 286 KESSER 291
>sp|Q63796|M3K12_RAT Mitogen-activated protein kinase kinase kinase
12 OS=Rattus norvegicus OX=10116 GN=Map3k12 PE=1 SV=1
Length=888
Score = 102 bits (254), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 79/262 (30%), Positives = 115/262 (44%), Gaps = 37/262 (14%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
GE VAVK + R + +I LR L H +II +KG C ++ME+
Sbjct 179 GEEVAVKKV--------RDLKETDIKHLRKLKHPNIITFKGVCTQA--PCYCILMEFCAQ 228
Query 984 GSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
G L + L + + L+ ++ I GM YLH IHRDL + N+L+ D +VKI DF
Sbjct 229 GQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDF 288
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
G +K + + + V W APE ++ D+WSFGV L+ELLT
Sbjct 289 GTSKELSD----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG----- 339
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
P K ++ I G + LP P CP L++ CW + RP+F
Sbjct 340 EIPYKDVDSSAIIWG---------VGSNSLHLPVPSSCPDGFKILLRQCWNRKPRNRPSF 390
Query 1163 ENLI--------PILKTVHEKY 1176
++ +L T E Y
Sbjct 391 RQILLHLDIASADVLSTPQETY 412
Score = 63.9 bits (154), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 71/260 (27%), Positives = 106/260 (41%), Gaps = 36/260 (14%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
GR G+E+ V KV D DI + ++ H ++ GVC + P ++ E+
Sbjct 175 GRFHGEEV-AVKKVRDLKETDI--------KHLRKLKHPNIITFKGVCTQAPCYCILMEF 225
Query 690 VEHGPLDVWLRRERGHVP---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
G L LR R P + W M +A ++YL ++H ++ N+L+
Sbjct 226 CAQGQLYEVLRAGRPVTPSLLVDWSMGIA----GGMNYLHLHKIIHRDLKSPNMLIT--- 278
Query 747 LAEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+K+SD G + ++ + W+APE + +S +D W FG
Sbjct 279 ----YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 332
Query 804 LLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFR 860
L E+ GE P + S LP PS CP L QC +P RPSFR
Sbjct 333 LWEL-LTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNRKPRNRPSFR 391
Query 861 TILRDLTRLQPHNLADVLTV 880
IL L ADVL+
Sbjct 392 QILLHLDIAS----ADVLST 407
>sp|O48814|BIK1_ARATH Serine/threonine-protein kinase BIK1 OS=Arabidopsis
thaliana OX=3702 GN=BIK1 PE=1 SV=1
Length=395
Score = 99.4 bits (246), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 92/290 (32%), Positives = 136/290 (47%), Gaps = 24/290 (8%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+GEG FG V D PT GTG ++AVK L + HR W EI+ L L H
Sbjct 73 IGEGGFGCVFKGWLDESTLTPTKPGTGLVIAVKKLNQEGFQGHRE-WLTEINYLGQLSHP 131
Query 958 HIIKYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLF-----AQQICEGM 1011
+++K G C ED+ LV E++ GSL ++L R L F A +G+
Sbjct 132 NLVKLIGYCLEDEHR---LLVYEFMQKGSLENHLFRRGAYFKPLPWFLRVNVALDAAKGL 188
Query 1012 AYLHAQ--HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH-EYYRVREDGDSPVFWY 1068
A+LH+ I+RD+ A N+LLD D K+ DFGLA+ P G Y R G +
Sbjct 189 AFLHSDPVKVIYRDIKASNILLDADYNAKLSDFGLARDGPMGDLSYVSTRVMGTYG--YA 246
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + SDV+SFGV L E+L+ + + P K L+ A+ +T R L
Sbjct 247 APEYMSSGHLNARSDVYSFGVLLLEILSGKRALDHNRPAKEENLVDWARPYLTSKRKVLL 306
Query 1128 L--ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+ R + P++ + + C E RPT + ++ L+ + +
Sbjct 307 IVDNRLDTQYLPEEA-VRMASVAVQCLSFEPKSRPTMDQVVRALQQLQDN 355
Score = 70.1 bits (170), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 76/291 (26%), Positives = 128/291 (44%), Gaps = 44/291 (15%)
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
DE L P + G L + +K L+ + + + Q+SH +L + G C+
Sbjct 87 DESTLTPTKP-GTGLVIAVKKLNQEGFQGHREWLTEINYLGQLSHPNLVKLIGYCLEDEH 145
Query 683 NIMVTEYVEHGPLDVWLRRERGHV-PMAW--KMVVAQQLASALSYLENK--NLVHGNVCG 737
++V E+++ G L+ L R + P+ W ++ VA A L++L + +++ ++
Sbjct 146 RLLVYEFMQKGSLENHLFRRGAYFKPLPWFLRVNVALDAAKGLAFLHSDPVKVIYRDIKA 205
Query 738 RNILLARLGLAEGTSPFIKLSDPGVG----LGALS--REERVERIPWLAPECLPGGANSL 791
NILL KLSD G+ +G LS + + APE + G L
Sbjct 206 SNILL-------DADYNAKLSDFGLARDGPMGDLSYVSTRVMGTYGYAAPEYMSSG--HL 256
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF------YQRQHR------------- 832
+ D + FG LLEI G+ L P+++E+ Y R
Sbjct 257 NARSDVYSFGVLLLEI-LSGKRALDHNRPAKEENLVDWARPYLTSKRKVLLIVDNRLDTQ 315
Query 833 -LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
LPE + ++A++ QCL++EP RP+ ++R L +LQ NL NP
Sbjct 316 YLPEEAV-RMASVAVQCLSFEPKSRPTMDQVVRALQQLQ-DNLGKPSQTNP 364
>sp|Q8IWU2|LMTK2_HUMAN Serine/threonine-protein kinase LMTK2 OS=Homo
sapiens OX=9606 GN=LMTK2 PE=1 SV=2
Length=1503
Score = 102 bits (255), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 90/286 (31%), Positives = 135/286 (47%), Gaps = 55/286 (19%)
Query 894 KRYLKKIRDLGEGHFGKVSL-YCYDPTNDGTGEMVA---VKALKADCGPQHRSGWKQEID 949
+ L I+++G G FGKV L Y TG VA VK LKA P+ + + + +
Sbjct 134 RHSLNYIQEIGNGWFGKVLLGEIY------TGTSVARVIVKELKASANPKEQDTFLKNGE 187
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQ 1006
L H +I++ G C + LV E+ LG L+ YL H G +Q +L +
Sbjct 188 PYYILQHPNILQCVGQCVEA--IPYLLVFEFCDLGDLKAYLRSEQEHMRGDSQTMLLQRM 245
Query 1007 ICE---GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED--- 1060
CE G+A +H H++H DLA RN L +D VK+GD+G+ + R +ED
Sbjct 246 ACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVKVGDYGIG--------FSRYKEDYIE 297
Query 1061 -GDSPVF---WYAPECLKEYKF-------YYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
D VF W APE + ++ S++WS GVTL+EL D++ P +
Sbjct 298 TDDKKVFPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVTLWELF---DNAAQPYSNLS 354
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPD-KCPCEV--YHLMKNCW 1152
L + Q V+R ER +LP+P + P Y +++ CW
Sbjct 355 NLDVLNQ----VIR-----ERDTKLPKPQLEQPYSDRWYEVLQFCW 391
Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 62/267 (23%), Positives = 116/267 (43%), Gaps = 37/267 (14%)
Query 638 RVVLKVL----DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
RV++K L +P D L E ++ H ++ G CV ++V E+ + G
Sbjct 164 RVIVKELKASANPKEQDTFLKNGEPYYILQ---HPNILQCVGQCVEAIPYLLVFEFCDLG 220
Query 694 PLDVWLRRERGHVPMAWKMVVAQ----QLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
L +LR E+ H+ + ++ Q ++A+ L+ + + +H ++ RN L
Sbjct 221 DLKAYLRSEQEHMRGDSQTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLT------ 274
Query 750 GTSPFIKLSDPGVGLGAL------SREERVERIPWLAPECLPGGANSLSTA-----MDKW 798
+ +K+ D G+G + +++V + W APE + + L TA + W
Sbjct 275 -SDLNVKVGDYGIGFSRYKEDYIETDDKKVFPLRWTAPELVTSFQDRLLTADQTKYSNIW 333
Query 799 GFGATLLEICFDGEAPLQSRSPSE--KEHFYQRQHRLPEPSCPQ-LATLTSQCLTY---E 852
G TL E+ + P + S + + +R +LP+P Q + + L +
Sbjct 334 SLGVTLWELFDNAAQPYSNLSNLDVLNQVIRERDTKLPKPQLEQPYSDRWYEVLQFCWLS 393
Query 853 PTQRPSFRTILRDLT--RLQPHNLADV 877
P +RP+ + R LT RLQ ++V
Sbjct 394 PEKRPAAEDVHRLLTYLRLQSQRDSEV 420
>sp|O81472|MP3K2_ARATH Mitogen-activated protein kinase kinase
kinase 9 OS=Arabidopsis thaliana OX=3702 GN=MEKK2 PE=1 SV=1
Length=773
Score = 102 bits (253), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 80/271 (30%), Positives = 134/271 (49%), Gaps = 34/271 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQ---EIDILRTLYHEH 958
L +G FG V Y+ ++ G+ AVK + D G Q + +Q EI +L L H++
Sbjct 507 LRQGSFGSV----YEAISED-GDFFAVKEVSLLDQGSQAQECIQQLEGEIALLSQLEHQN 561
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I++Y+G D+ +L + +E V GSL + R+ I + + L+ +QI +G+ YLH +
Sbjct 562 ILRYRGT--DKDGSNLYIFLELVTQGSLLELYRRYQIRDSLISLYTKQILDGLKYLHHKG 619
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL--KEY 1076
+IHRD+ +L+D + VK+ DFGLAK V + ++ +E +FW APE + K+
Sbjct 620 FIHRDIKCATILVDANGTVKLADFGLAK-VSKLNDIKSRKE----TLFWMAPEVINRKDN 674
Query 1077 KFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
Y + +D+WS G T+ E+ T Q P + + + + + RG
Sbjct 675 DGYRSPADIWSLGCTVLEMCT----GQIPYSDLEPVEALFR-----------IRRGTLPE 719
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
PD + H + C + RPT L+
Sbjct 720 VPDTLSLDARHFILKCLKLNPEERPTATELL 750
Score = 62.8 bits (151), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 60/214 (28%), Positives = 95/214 (44%), Gaps = 25/214 (12%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
+L+SQ+ H ++ G G + E V G L RR + + + +Q+
Sbjct 552 ALLSQLEHQNILRYRGTDKDGSNLYIFLELVTQGSLLELYRRY--QIRDSLISLYTKQIL 609
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR----EERVER 775
L YL +K +H ++ IL+ A GT +KL+D GL +S+ + R E
Sbjct 610 DGLKYLHHKGFIHRDIKCATILVD----ANGT---VKLAD--FGLAKVSKLNDIKSRKET 660
Query 776 IPWLAPECLPGGANS-LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834
+ W+APE + N + D W G T+LE+C G+ P P E F R+ LP
Sbjct 661 LFWMAPEVINRKDNDGYRSPADIWSLGCTVLEMCT-GQIPYSDLEPVEA-LFRIRRGTLP 718
Query 835 EPSCPQLATLTS-----QCLTYEPTQRPSFRTIL 863
E P +L + +CL P +RP+ +L
Sbjct 719 E--VPDTLSLDARHFILKCLKLNPEERPTATELL 750
>sp|Q9UL54|TAOK2_HUMAN Serine/threonine-protein kinase TAO2 OS=Homo
sapiens OX=9606 GN=TAOK2 PE=1 SV=2
Length=1235
Score = 102 bits (254), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 80/242 (33%), Positives = 121/242 (50%), Gaps = 32/242 (13%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDI 950
++ +R++G G FG V + D N E+VA+K + + G Q W+ +E+
Sbjct 25 EKLFSDLREIGHGSFGAV-YFARDVRNS---EVVAIKKM-SYSGKQSNEKWQDIIKEVRF 79
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQIC 1008
L+ L H + I+Y+GC E + LVMEY LGS D L H L ++ + A
Sbjct 80 LQKLRHPNTIQYRGCYLR--EHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAVTHGAL 136
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+G+AYLH+ + IHRD+ A N+LL LVK+GDFG A + + + +P +W
Sbjct 137 QGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSFV------GTP-YWM 189
Query 1069 APE---CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP----TKFLELIGIAQGQMTV 1121
APE + E ++ DVWS G+T EL + + PP L IAQ + V
Sbjct 190 APEVILAMDEGQYDGKVDVWSLGITCIEL-----AERKPPLFNMNAMSALYHIAQNESPV 244
Query 1122 LR 1123
L+
Sbjct 245 LQ 246
Score = 38.9 bits (89), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 44/186 (24%), Positives = 68/186 (37%), Gaps = 14/186 (8%)
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780
L+YL + N++H +V NILL+ GL +KL D G V W+A
Sbjct 138 GLAYLHSHNMIHRDVKAGNILLSEPGL-------VKLGDFGSASIMAPANSFVGTPYWMA 190
Query 781 PEC-LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-- 837
PE L +D W G T +E+ + S H Q + + +
Sbjct 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHW 250
Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRD---LTRLQPHNLADVLTVNPDSPASDPTVFHK 894
CL P RP+ +L+ L P + D++ D+ +
Sbjct 251 SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA-VRELDNLQY 309
Query 895 RYLKKI 900
R +KKI
Sbjct 310 RKMKKI 315
>sp|Q56UN5|M3K19_HUMAN Mitogen-activated protein kinase kinase
kinase 19 OS=Homo sapiens OX=9606 GN=MAP3K19 PE=2 SV=1
Length=1328
Score = 102 bits (254), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 63/205 (31%), Positives = 109/205 (53%), Gaps = 20/205 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-----CGPQHRSGWKQEIDILRTLYHE 957
LG+G +G V YC + G+++AVK + D + ++E+D+L+ L H
Sbjct 1067 LGKGAYGTV--YCGLTSQ---GQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHV 1121
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--FAQQICEGMAYLH 1015
+I+ Y G C E ++ + ME+VP GS+ + R L +++ + +QI +G+AYLH
Sbjct 1122 NIVAYLGTC--LQENTVSIFMEFVPGGSISSIINRFG-PLPEMVFCKYTKQILQGVAYLH 1178
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP----EGHEYYRVREDGDSPVFWYAPE 1071
+HRD+ NV+L ++K+ DFG A+ + G ++ +P +W APE
Sbjct 1179 ENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTP-YWMAPE 1237
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
+ E + SD+WS G T++E+ T
Sbjct 1238 VINESGYGRKSDIWSIGCTVFEMAT 1262
Score = 53.9 bits (128), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 63/251 (25%), Positives = 101/251 (40%), Gaps = 31/251 (12%)
Query 633 RGQELRVVLKVLDPSHHDIALAFY----ETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+GQ + V LD S+ A Y E L+ + H ++ G C++ + E
Sbjct 1082 QGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFME 1141
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+V G + + R G +P +Q+ ++YL +VH ++ G N++L G+
Sbjct 1142 FVPGGSISSIINR-FGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGI- 1199
Query 749 EGTSPFIKLSDPG-------VGLGALSRE--ERVERIP-WLAPECLPGGANSLSTAMDKW 798
IKL D G GL + + + P W+APE + + D W
Sbjct 1200 ------IKLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVI--NESGYGRKSDIW 1251
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-----LPEPSCPQLATLTSQCLTYEP 853
G T+ E+ G+ PL S FY HR LP+ A CLT +
Sbjct 1252 SIGCTVFEMA-TGKPPLASMD-RMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQ 1309
Query 854 TQRPSFRTILR 864
+RPS +L+
Sbjct 1310 HERPSALQLLK 1320
>sp|P11345|RAF1_RAT RAF proto-oncogene serine/threonine-protein
kinase OS=Rattus norvegicus OX=10116 GN=Raf1 PE=1 SV=1
Length=648
Score = 101 bits (251), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 69/200 (35%), Positives = 102/200 (51%), Gaps = 17/200 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+
Sbjct 355 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILL 407
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++
Sbjct 408 FMGY---MTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 464
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076
IHRD+ + N+ L VKIGDFGLA +V + S V W APE ++
Sbjct 465 IHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-VLWMAPEVIRMQDNN 523
Query 1077 KFYYASDVWSFGVTLYELLT 1096
F + SDV+S+G+ LYEL+T
Sbjct 524 PFSFQSDVYSYGIVLYELMT 543
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 70/286 (24%), Positives = 128/286 (45%), Gaps = 32/286 (11%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688
G+ G +LKV+DP+ + AF +++ + H ++ G + +N+ +VT+
Sbjct 366 GKWHGDVAVKILKVVDPTPEQLQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 422
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ E L L + M + +A+Q A + YL KN++H ++ NI L
Sbjct 423 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF-----LH 477
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANS-LSTAMDKWGFG 801
EG + +K+ D G+ G+ E+ + W+APE + N+ S D + +G
Sbjct 478 EGLT--VKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYG 535
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854
L E+ GE P + ++ F R + P+ S CP+ + L + C+
Sbjct 536 IVLYEL-MTGELPYSHINNRDQIIFMVGRGYASPDLSRLYKNCPKAMKRLVADCVKKVKE 594
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+RP F IL + LQ H+L + + AS+P++ + + I
Sbjct 595 ERPLFPQILSSIELLQ-HSLPKI-----NRSASEPSLHRAAHTEDI 634
>sp|Q869T7|PAKF_DICDI Serine/threonine-protein kinase pakF OS=Dictyostelium
discoideum OX=44689 GN=pakF PE=3 SV=1
Length=1176
Score = 102 bits (254), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 59/194 (30%), Positives = 105/194 (54%), Gaps = 13/194 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G +G V Y T+ G +A+K + + + EI+IL+ +I+ Y
Sbjct 400 LGDGAYGSV----YKGTHKDLGFTLAIKVI--EMKESESVSLQNEINILKNCKSPNIVSY 453
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G Q E + +++++ LGS+RD + ++ AQ+ + +G+ YLH+Q+ I
Sbjct 454 FGSL--QTESHIWILLDFCALGSIRDIIESTEKTLNEAQISFVVKNTLKGLIYLHSQNII 511
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ A NVLL VKI DFG+++ + + + +E +P+ W APE + + + Y
Sbjct 512 HRDVKAANVLLSEGCDVKIADFGVSEKLNGALD--QSKEMIGTPL-WMAPEVILKKNYDY 568
Query 1081 ASDVWSFGVTLYEL 1094
+D+WS G+T+ E+
Sbjct 569 KADIWSLGITIIEM 582
Score = 42.0 bits (97), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 41/153 (27%), Positives = 66/153 (43%), Gaps = 18/153 (12%)
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSRE 770
V + L YL ++N++H +V N+L L+EG +K++D GV GAL +
Sbjct 494 VVKNTLKGLIYLHSQNIIHRDVKAANVL-----LSEGCD--VKIADFGVSEKLNGALDQS 546
Query 771 ERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
+ + P W+APE + + D W G T++E+ DG P P
Sbjct 547 KEMIGTPLWMAPEVI--LKKNYDYKADIWSLGITIIEMA-DGLPPHIDLPPMRAMKMVPN 603
Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPS 858
P+ P L ++CL +P +R S
Sbjct 604 WPPPTFAEPKKWSPLLNDFLARCLVKDPEKRAS 636
>sp|P05625|RAF1_CHICK RAF proto-oncogene serine/threonine-protein
kinase OS=Gallus gallus OX=9031 GN=RAF1 PE=2 SV=1
Length=647
Score = 101 bits (251), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 68/200 (34%), Positives = 102/200 (51%), Gaps = 17/200 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+
Sbjct 355 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILL 407
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++
Sbjct 408 FMGY---MTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 464
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076
IHRD+ + N+ L VKIGDFGLA +V + S + W APE ++
Sbjct 465 IHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-ILWMAPEVIRMQDSN 523
Query 1077 KFYYASDVWSFGVTLYELLT 1096
F + SDV+S+G+ LYEL+T
Sbjct 524 PFSFQSDVYSYGIVLYELMT 543
Score = 65.1 bits (157), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 72/286 (25%), Positives = 127/286 (44%), Gaps = 32/286 (11%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688
G+ G +LKV+DP+ AF +++ + H ++ G + +N+ +VT+
Sbjct 366 GKWHGDVAVKILKVVDPTPEQFQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 422
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ E L L + M + +A+Q A + YL KN++H ++ NI L
Sbjct 423 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF-----LH 477
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFG 801
EG + +K+ D G+ G+ E+ I W+APE + +N S D + +G
Sbjct 478 EGLT--VKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYG 535
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854
L E+ GE P + ++ F R + P+ S CP+ + L + CL
Sbjct 536 IVLYEL-MTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVRE 594
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+RP F IL + LQ H+L + + AS+P++ + + I
Sbjct 595 ERPLFPQILSSIELLQ-HSLPKI-----NRSASEPSLHRASHTEDI 634
>sp|Q6ZQ29|TAOK2_MOUSE Serine/threonine-protein kinase TAO2 OS=Mus
musculus OX=10090 GN=Taok2 PE=1 SV=3
Length=1240
Score = 102 bits (253), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 72/209 (34%), Positives = 109/209 (52%), Gaps = 23/209 (11%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDI 950
++ +R++G G FG V + D N E+VA+K + + G Q W+ +E+
Sbjct 25 EKLFSDLREIGHGSFGAV-YFARDVRNS---EVVAIKKM-SYSGKQSNEKWQDIIKEVRF 79
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQIC 1008
L+ L H + I+Y+GC E + LVMEY LGS D L H L ++ + A
Sbjct 80 LQKLRHPNTIQYRGCYLR--EHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAVTHGAL 136
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+G+AYLH+ + IHRD+ A N+LL LVK+GDFG A + + + +P +W
Sbjct 137 QGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSFV------GTP-YWM 189
Query 1069 APE---CLKEYKFYYASDVWSFGVTLYEL 1094
APE + E ++ DVWS G+T EL
Sbjct 190 APEVILAMDEGQYDGKVDVWSLGITCIEL 218
Score = 37.7 bits (86), Expect = 0.81, Method: Compositional matrix adjust.
Identities = 44/186 (24%), Positives = 67/186 (36%), Gaps = 14/186 (8%)
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780
L+YL + N++H +V NILL+ GL +KL D G V W+A
Sbjct 138 GLAYLHSHNMIHRDVKAGNILLSEPGL-------VKLGDFGSASIMAPANSFVGTPYWMA 190
Query 781 PEC-LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-- 837
PE L +D W G T +E+ + S H Q + +
Sbjct 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPALQSGHW 250
Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRD---LTRLQPHNLADVLTVNPDSPASDPTVFHK 894
CL P RP+ +L+ L P + D++ D+ +
Sbjct 251 SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA-VRELDNLQY 309
Query 895 RYLKKI 900
R +KKI
Sbjct 310 RKMKKI 315
>sp|Q5R5M7|RAF1_PONAB RAF proto-oncogene serine/threonine-protein
kinase OS=Pongo abelii OX=9601 GN=RAF1 PE=2 SV=1
Length=648
Score = 100 bits (250), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 69/200 (35%), Positives = 102/200 (51%), Gaps = 17/200 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+
Sbjct 355 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILL 407
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++
Sbjct 408 FMGY---MTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 464
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076
IHRD+ + N+ L VKIGDFGLA +V + S V W APE ++
Sbjct 465 IHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-VLWMAPEVIRMQDNN 523
Query 1077 KFYYASDVWSFGVTLYELLT 1096
F + SDV+S+G+ LYEL+T
Sbjct 524 PFSFQSDVYSYGIVLYELMT 543
Score = 63.5 bits (153), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 70/286 (24%), Positives = 127/286 (44%), Gaps = 32/286 (11%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688
G+ G +LKV+DP+ AF +++ + H ++ G + +N+ +VT+
Sbjct 366 GKWHGDVAVKILKVVDPTPEQFQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 422
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ E L L + M + +A+Q A + YL KN++H ++ NI L
Sbjct 423 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF-----LH 477
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANS-LSTAMDKWGFG 801
EG + +K+ D G+ G+ E+ + W+APE + N+ S D + +G
Sbjct 478 EGLT--VKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYG 535
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854
L E+ GE P + ++ F R + P+ S CP+ + L + C+
Sbjct 536 IVLYEL-MTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKE 594
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+RP F IL + LQ H+L + + AS+P++ + + I
Sbjct 595 ERPLFPQILSSIELLQ-HSLPKI-----NRSASEPSLHRAAHTEDI 634
>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein
kinase OS=Homo sapiens OX=9606 GN=RAF1 PE=1 SV=1
Length=648
Score = 100 bits (250), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 69/200 (35%), Positives = 102/200 (51%), Gaps = 17/200 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+
Sbjct 355 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILL 407
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++
Sbjct 408 FMGY---MTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 464
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076
IHRD+ + N+ L VKIGDFGLA +V + S V W APE ++
Sbjct 465 IHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-VLWMAPEVIRMQDNN 523
Query 1077 KFYYASDVWSFGVTLYELLT 1096
F + SDV+S+G+ LYEL+T
Sbjct 524 PFSFQSDVYSYGIVLYELMT 543
Score = 63.5 bits (153), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 70/286 (24%), Positives = 127/286 (44%), Gaps = 32/286 (11%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688
G+ G +LKV+DP+ AF +++ + H ++ G + +N+ +VT+
Sbjct 366 GKWHGDVAVKILKVVDPTPEQFQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 422
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ E L L + M + +A+Q A + YL KN++H ++ NI L
Sbjct 423 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF-----LH 477
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANS-LSTAMDKWGFG 801
EG + +K+ D G+ G+ E+ + W+APE + N+ S D + +G
Sbjct 478 EGLT--VKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYG 535
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854
L E+ GE P + ++ F R + P+ S CP+ + L + C+
Sbjct 536 IVLYEL-MTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKE 594
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+RP F IL + LQ H+L + + AS+P++ + + I
Sbjct 595 ERPLFPQILSSIELLQ-HSLPKI-----NRSASEPSLHRAAHTEDI 634
>sp|Q9C5H5|M3K5G_ARATH Mitogen-activated protein kinase kinase
kinase 5 OS=Arabidopsis thaliana OX=3702 GN=MAPKKK5 PE=1 SV=1
Length=716
Score = 101 bits (251), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 82/286 (29%), Positives = 134/286 (47%), Gaps = 47/286 (16%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK--------ADCGPQHRSGWKQEID 949
KK + +G G FG V Y +N TG + A+K ++ A+C Q +QEI
Sbjct 347 KKGKLIGRGTFGSV----YVASNSETGALCAMKEVELFPDDPKSAECIKQ----LEQEIK 398
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--FAQQI 1007
+L L H +I++Y G + E + +EYV GS+ Y+ H + + ++ F + I
Sbjct 399 LLSNLQHPNIVQYFGS--ETVEDRFFIYLEYVHPGSINKYIRDHCGTMTESVVRNFTRHI 456
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
G+AYLH + +HRD+ N+L+D +VK+ DFG+AK + ++ SP +W
Sbjct 457 LSGLAYLHNKKTVHRDIKGANLLVDASGVVKLADFGMAKHLTGQRADLSLK---GSP-YW 512
Query 1068 YAPECLKEY-------KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
APE ++ +A D+WS G T+ E+ T PP + E G A
Sbjct 513 MAPELMQAVMQKDSNPDLAFAVDIWSLGCTIIEMFTG-----KPP--WSEFEGAA-AMFK 564
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
V+R + P P+ E ++ C++ + RPT L+
Sbjct 565 VMR--------DSPPIPESMSPEGKDFLRLCFQRNPAERPTASMLL 602
Score = 57.4 bits (137), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 17/228 (7%)
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
DP + + L+S + H ++ G + EYV G ++ ++R G
Sbjct 383 DPKSAECIKQLEQEIKLLSNLQHPNIVQYFGSETVEDRFFIYLEYVHPGSINKYIRDHCG 442
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763
+ + + + S L+YL NK VH ++ G N+L+ G+ +KL+D G+
Sbjct 443 TMTESVVRNFTRHILSGLAYLHNKKTVHRDIKGANLLVDASGV-------VKLADFGMAK 495
Query 764 -LGALSREERVERIP-WLAPECLPG-----GANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
L + ++ P W+APE + L+ A+D W G T++E+ F G+ P
Sbjct 496 HLTGQRADLSLKGSPYWMAPELMQAVMQKDSNPDLAFAVDIWSLGCTIIEM-FTGKPPWS 554
Query 817 SRSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
+ R +PE P+ C P +RP+ +L
Sbjct 555 EFEGAAAMFKVMRDSPPIPESMSPEGKDFLRLCFQRNPAERPTASMLL 602
>sp|A7MBB4|M3K13_BOVIN Mitogen-activated protein kinase kinase
kinase 13 OS=Bos taurus OX=9913 GN=MAP3K13 PE=2 SV=1
Length=966
Score = 101 bits (252), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 83/273 (30%), Positives = 120/273 (44%), Gaps = 39/273 (14%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI--LRTL 954
+ +++ LG G G V L + E VA+K ++ + E DI LR L
Sbjct 168 ISELQWLGSGAQGAVFLGKF------RAEEVAIKKVRE----------QNETDIKHLRKL 211
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAY 1013
H +II +KG C ++MEY G L + L +LL+ ++ I GM Y
Sbjct 212 KHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNY 269
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
LH IHRDL + NVL+ + VKI DFG +K + + + V W APE +
Sbjct 270 LHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDK----STKMSFAGTVAWMAPEVI 325
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ D+WSFGV L+ELLT P K ++ I G +
Sbjct 326 RNEPVSEKVDIWSFGVVLWELLT-----GEIPYKDVDSSAIIWG---------VGSNSLH 371
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
LP P CP LMK W+++ RP+F +
Sbjct 372 LPVPSTCPDGFKILMKQTWQSKTRNRPSFRQTL 404
Score = 62.0 bits (149), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 74/308 (24%), Positives = 119/308 (39%), Gaps = 54/308 (18%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+A L Q V +EI++L LG G + V+ G+ R E
Sbjct 146 GKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAEEVA------------ 193
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+ KV + + DI + ++ H ++ GVC + P ++
Sbjct 194 -------------IKKVREQNETDI--------KHLRKLKHPNIIAFKGVCTQAPCYCII 232
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLAR 744
EY HG L LR R P +++V + +AS ++YL ++H ++ N+L+
Sbjct 233 MEYCAHGQLYEVLRAGRKITP---RLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTH 289
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFG 801
+ +K+SD G + ++ + W+APE + +S +D W FG
Sbjct 290 -------TDAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFG 340
Query 802 ATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPS 858
L E+ GE P + S LP PS CP L Q + RPS
Sbjct 341 VVLWEL-LTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKTRNRPS 399
Query 859 FRTILRDL 866
FR L L
Sbjct 400 FRQTLMHL 407
>sp|Q54JG7|DST4_DICDI Serine/threonine-protein kinase dst4 OS=Dictyostelium
discoideum OX=44689 GN=dst4 PE=3 SV=1
Length=485
Score = 99.8 bits (247), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 85/294 (29%), Positives = 136/294 (46%), Gaps = 33/294 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR-TLYHEHIIK 961
+G+G FG V C + N+ E+VA+K L+ + + S K+EI IL+ T+ +I+K
Sbjct 27 IGQGSFG-VVCTCINTVNN---EVVAIKFLEME--GEENSSLKKEITILKNTVRCPYIVK 80
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHY 1019
Y GC E +L +VMEY GS+ D + SI L AQ+ QI EG+ YLH+
Sbjct 81 YHGCYIK--ENNLMIVMEYCDGGSILDIMQMCSITLTEAQIAAILYQIVEGLVYLHSNKI 138
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK-- 1077
+HRD+ A NVL++ K+ DFG++ + + ++ + SP +W +PE + K
Sbjct 139 LHRDIKAGNVLVNKLGQAKLADFGVSAILV--NTGFKQKTVVGSP-YWMSPEVISPPKGS 195
Query 1078 --FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ +D+WS G+T E+ + PP L + + + L
Sbjct 196 NGYDSKADIWSLGITAIEM-----AESKPPLFNLNPVKVI--------FVIPFRQAPTLE 242
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAPSVFSVC 1187
P E + C EA RP+ +L+ P +K E Q + C
Sbjct 243 VPGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFIKKGKEHSQPTISEMVEQC 296
Score = 59.3 bits (142), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 55/236 (23%), Positives = 105/236 (44%), Gaps = 18/236 (8%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K L+ + + E L + V ++ HG ++ ++V EY + G +
Sbjct 47 VAIKFLEMEGEENSSLKKEITILKNTVRCPYIVKYHGCYIKENNLMIVMEYCDGGSILDI 106
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
++ + A + Q+ L YL + ++H ++ N+L+ +LG A KL+
Sbjct 107 MQMCSITLTEAQIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQA-------KLA 159
Query 759 DPGVGLGALS---REERVERIP-WLAPECL--PGGANSLSTAMDKWGFGATLLEICFDGE 812
D GV ++ +++ V P W++PE + P G+N + D W G T +E+ + +
Sbjct 160 DFGVSAILVNTGFKQKTVVGSPYWMSPEVISPPKGSNGYDSKADIWSLGITAIEMA-ESK 218
Query 813 APLQSRSPSEKEHF--YQRQHRLPEPS--CPQLATLTSQCLTYEPTQRPSFRTILR 864
PL + +P + +++ L P P+ S CL E +RPS +L
Sbjct 219 PPLFNLNPVKVIFVIPFRQAPTLEVPGNWSPEFNDFISVCLNKEADKRPSAVDLLN 274
>sp|Q9JLS3|TAOK2_RAT Serine/threonine-protein kinase TAO2 OS=Rattus
norvegicus OX=10116 GN=Taok2 PE=1 SV=1
Length=1235
Score = 101 bits (252), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 72/209 (34%), Positives = 109/209 (52%), Gaps = 23/209 (11%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDI 950
++ +R++G G FG V + D N E+VA+K + + G Q W+ +E+
Sbjct 25 EKLFSDLREIGHGSFGAV-YFARDVRNS---EVVAIKKM-SYSGKQSNEKWQDIIKEVRF 79
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQIC 1008
L+ L H + I+Y+GC E + LVMEY LGS D L H L ++ + A
Sbjct 80 LQKLRHPNTIQYRGCYLR--EHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAVTHGAL 136
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+G+AYLH+ + IHRD+ A N+LL LVK+GDFG A + + + +P +W
Sbjct 137 QGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSFV------GTP-YWM 189
Query 1069 APE---CLKEYKFYYASDVWSFGVTLYEL 1094
APE + E ++ DVWS G+T EL
Sbjct 190 APEVILAMDEGQYDGKVDVWSLGITCIEL 218
Score = 38.1 bits (87), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 44/186 (24%), Positives = 67/186 (36%), Gaps = 14/186 (8%)
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780
L+YL + N++H +V NILL+ GL +KL D G V W+A
Sbjct 138 GLAYLHSHNMIHRDVKAGNILLSEPGL-------VKLGDFGSASIMAPANSFVGTPYWMA 190
Query 781 PEC-LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-- 837
PE L +D W G T +E+ + S H Q + +
Sbjct 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPALQSGHW 250
Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRD---LTRLQPHNLADVLTVNPDSPASDPTVFHK 894
CL P RP+ +L+ L P + D++ D+ +
Sbjct 251 SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA-VRELDNLQY 309
Query 895 RYLKKI 900
R +KKI
Sbjct 310 RKMKKI 315
>sp|P20792|DAF1_CAEEL Cell surface receptor daf-1 OS=Caenorhabditis
elegans OX=6239 GN=daf-1 PE=1 SV=1
Length=669
Score = 100 bits (250), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 105/372 (28%), Positives = 157/372 (42%), Gaps = 73/372 (20%)
Query 837 SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASD--PTVFHK 894
S P++A + Q T + SF + P+N+ D+L V ++ S PT HK
Sbjct 233 SVPEVAPIEQQGSTMSTSAGNSFPP------GIMPNNMKDMLDVLEETSGSGMGPTTLHK 286
Query 895 RYLK-KIR---DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+ +IR +G G FG VS D GE VAVK A P + EI
Sbjct 287 LTIGGQIRLTGRVGSGRFGNVS------RGDYRGEAVAVKVFNALDEPAFHK--ETEIFE 338
Query 951 LRTLYHEHIIKYKGCCE-DQG-EKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008
R L H ++++Y G D G L LV EY P GSL D+L +++ + +
Sbjct 339 TRMLRHPNVLRYIGSDRVDTGFVTELWLVTEYHPSGSLHDFLLENTVNIETYYNLMRSTA 398
Query 1009 EGMAYLHAQ----------HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-------G 1051
G+A+LH Q HRD+ ++N+++ ND IGD GL+ + PE
Sbjct 399 SGLAFLHNQIGGSKESNKPAMAHRDIKSKNIMVKNDLTCAIGDLGLSLSKPEDAASDIIA 458
Query 1052 HEYYRVREDGDSPVFWYAPECLKE------YKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+E Y+ V + APE L ++ Y +DV+SF + ++E L C+ P
Sbjct 459 NENYKC-----GTVRYLAPEILNSTMQFTVFESYQCADVYSFSLVMWETLCRCEDGDVLP 513
Query 1106 TKFLELIGIAQ--------GQMTVLRLTELLERGERLPRPDKCPC-----EVYHLM---K 1149
+ +I + QM + T L RP + P E+ H+M K
Sbjct 514 REAATVIPYIEWTDRDPQDAQMFDVVCTRRL-------RPTENPLWKDHPEMKHIMEIIK 566
Query 1150 NCWETEASFRPT 1161
CW S R T
Sbjct 567 TCWNGNPSARFT 578
>sp|Q1HKZ5|M3K13_MOUSE Mitogen-activated protein kinase kinase
kinase 13 OS=Mus musculus OX=10090 GN=Map3k13 PE=1 SV=1
Length=959
Score = 101 bits (251), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 83/273 (30%), Positives = 120/273 (44%), Gaps = 39/273 (14%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI--LRTL 954
+ +++ LG G G V L + E VA+K ++ + E DI LR L
Sbjct 167 ISELQWLGSGAQGAVFLGKF------RAEEVAIKKVRE----------QNETDIKHLRKL 210
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAY 1013
H +II +KG C ++MEY G L + L +LL+ ++ I GM Y
Sbjct 211 KHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNY 268
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
LH IHRDL + NVL+ + VKI DFG +K + + + V W APE +
Sbjct 269 LHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSD----KSTKMSFAGTVAWMAPEVI 324
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ D+WSFGV L+ELLT P K ++ I G +
Sbjct 325 RNEPVSEKVDIWSFGVVLWELLT-----GEIPYKDVDSSAIIWG---------VGSNSLH 370
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
LP P CP LMK W+++ RP+F +
Sbjct 371 LPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTL 403
Score = 64.3 bits (155), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 74/299 (25%), Positives = 118/299 (39%), Gaps = 54/299 (18%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L Q V +EI++L LG G + V+ G+ R E
Sbjct 154 LQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAEEV---------------------- 191
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+ KV + + DI + ++ H ++ GVC + P ++ EY HG L
Sbjct 192 ---AIKKVREQNETDI--------KHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQL 240
Query 696 DVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
LR R P +++V + +AS ++YL ++H ++ N+L+ +
Sbjct 241 YEVLRAGRKITP---RLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTH-------TD 290
Query 754 FIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+K+SD G + ++ + W+APE + +S +D W FG L E+
Sbjct 291 AVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVVLWEL-LT 347
Query 811 GEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866
GE P + S LP PS CP L Q +P RPSFR L L
Sbjct 348 GEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHL 406
>sp|Q54XQ2|RCKA_DICDI RGS domain-containing serine/threonine-protein
kinase A OS=Dictyostelium discoideum OX=44689 GN=rckA
PE=1 SV=1
Length=1125
Score = 101 bits (252), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 69/252 (27%), Positives = 118/252 (47%), Gaps = 25/252 (10%)
Query 924 GEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982
G+ VA+K L + C + +K+E+ ++ H+++ + G + +K L EY
Sbjct 863 GKDVAIKVLGPEVCVHFDLNEFKREVALMSIFKHDNLARCLGAGQ-YDDKYFHLT-EYCH 920
Query 983 LGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040
GSL YL R++I Q L FA I GM YLH+ IHRDL + N+LL +KI
Sbjct 921 NGSLFSYLRDQRNNISFGQRLHFALGIARGMRYLHSMSIIHRDLKSMNILLTKRLKIKIV 980
Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100
DFG ++ ++Y G W APE + DV+S+ + L+E+ T
Sbjct 981 DFGTSRV---ANKYNMTTHVGTQA--WMAPEIFTSRTYTNKVDVYSYAIILFEIFTRKS- 1034
Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
A + + + ++ +GER P + +++K CW+ + S RP
Sbjct 1035 --------------AYDENANINIPNMVMKGERPELPKDMQTSISNIIKKCWQQKPSNRP 1080
Query 1161 TFENLIPILKTV 1172
+F ++ L+++
Sbjct 1081 SFIKIVAYLESI 1092
Score = 67.0 bits (162), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 61/242 (25%), Positives = 108/242 (45%), Gaps = 22/242 (9%)
Query 630 GRDRGQELRVVLKVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
G+ +G++ V +KVL P H D+ F +LMS H +LA G + +
Sbjct 859 GQYKGKD--VAIKVLGPEVCVHFDLN-EFKREVALMSIFKHDNLARCLGAGQYDDKYFHL 915
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA-RL 745
TEY +G L +LR +R ++ ++ A +A + YL + +++H ++ NILL RL
Sbjct 916 TEYCHNGSLFSYLRDQRNNISFGQRLHFALGIARGMRYLHSMSIIHRDLKSMNILLTKRL 975
Query 746 GLAEGTSPFIKLSDPGVGLGA--LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
IK+ D G A + V W+APE + + + +D + +
Sbjct 976 K--------IKIVDFGTSRVANKYNMTTHVGTQAWMAPEIF--TSRTYTNKVDVYSYAII 1025
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRT 861
L EI F ++ + + + R LP+ ++ + +C +P+ RPSF
Sbjct 1026 LFEI-FTRKSAYDENANINIPNMVMKGERPELPKDMQTSISNIIKKCWQQKPSNRPSFIK 1084
Query 862 IL 863
I+
Sbjct 1085 IV 1086
>sp|O14305|SID1_SCHPO Serine/threonine-protein kinase sid1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=sid1 PE=1 SV=1
Length=471
Score = 99.4 bits (246), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 57/196 (29%), Positives = 102/196 (52%), Gaps = 10/196 (5%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+R LG G FG V + + +G+++A+K + + G + +QE+ +L ++
Sbjct 12 LRKLGSGSFGVV----WKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLSNCNSSNV 67
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I+Y GC D +L ++ME++ GS+ L + + + +++ G+ YLH Q+
Sbjct 68 IQYYGCFVDG--YTLWILMEHMDGGSVSGLLKMGRLNEQVISIILREVLYGLNYLHGQNK 125
Query 1020 IHRDLAARNVLLDNDR-LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ A N+LL + VK+ DFG+A + R FW APE +++ +
Sbjct 126 IHRDIKAANILLSSSTGNVKLADFGVAAQLSNAASR---RHTFVGTPFWMAPEVIQQTSY 182
Query 1079 YYASDVWSFGVTLYEL 1094
A+D+WS G+T E+
Sbjct 183 GLAADIWSLGITAIEM 198
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 52/221 (24%), Positives = 93/221 (42%), Gaps = 39/221 (18%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
++S + +++ +G V G ++ E+++ G + L+ R + + ++ +++
Sbjct 58 MLSNCNSSNVIQYYGCFVDGYTLWILMEHMDGGSVSGLLKMGRLNEQVI--SIILREVLY 115
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---GALSREERVERIP 777
L+YL +N +H ++ NILL+ ++ +KL+D GV A SR P
Sbjct 116 GLNYLHGQNKIHRDIKAANILLS------SSTGNVKLADFGVAAQLSNAASRRHTFVGTP 169
Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL-------------QSRSPSEK 823
W+APE + + L A D W G T +E+ +G P QS P
Sbjct 170 FWMAPEVIQQTSYGL--AADIWSLGITAIEMA-NGIPPRATMHPMRVIFEIPQSEPPKLD 226
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+HF P S CL P R S + +L+
Sbjct 227 DHF-----------SPTFRDFVSCCLDLNPNMRWSAKELLQ 256
>sp|P43293|PBL11_ARATH Probable serine/threonine-protein kinase
PBL11 OS=Arabidopsis thaliana OX=3702 GN=PBL11 PE=1 SV=2
Length=389
Score = 98.2 bits (243), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 95/292 (33%), Positives = 140/292 (48%), Gaps = 32/292 (11%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+GEG FG V D P+ GTG ++AVK L + HR W EI+ L L H
Sbjct 74 VGEGGFGCVFKGWIDESSLAPSKPGTGIVIAVKRLNQEGFQGHRE-WLAEINYLGQLDHP 132
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMA 1012
+++K G C + E+ LV E++ GSL ++L R L + A G+A
Sbjct 133 NLVKLIGYCLE--EEHRLLVYEFMTRGSLENHLFRRGTFYQPLSWNTRVRMALGAARGLA 190
Query 1013 YLH-AQ-HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG-HEYYRVREDGDSPVFWYA 1069
+LH AQ I+RD A N+LLD++ K+ DFGLA+ P G + + R G + A
Sbjct 191 FLHNAQPQVIYRDFKASNILLDSNYNAKLSDFGLARDGPMGDNSHVSTRVMGTQG--YAA 248
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT---HCDSSQSPPTKFLELIGIAQGQMT----VL 1122
PE L SDV+SFGV L ELL+ D +Q P L+ A+ +T +L
Sbjct 249 PEYLATGHLSVKSDVYSFGVVLLELLSGRRAIDKNQ--PVGEHNLVDWARPYLTNKRRLL 306
Query 1123 RLTELLERGE-RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
R+ + +G+ L R K L +C +A RPT ++ ++ +H
Sbjct 307 RVMDPRLQGQYSLTRALKIAV----LALDCISIDAKSRPTMNEIVKTMEELH 354
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 68/290 (23%), Positives = 116/290 (40%), Gaps = 41/290 (14%)
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
DE L P + G + + +K L+ + + + Q+ H +L + G C+
Sbjct 88 DESSLAPSKP-GTGIVIAVKRLNQEGFQGHREWLAEINYLGQLDHPNLVKLIGYCLEEEH 146
Query 683 NIMVTEYVEHGPLDVWL-RRERGHVPMAWKMVVAQQLASA--LSYLENKN--LVHGNVCG 737
++V E++ G L+ L RR + P++W V L +A L++L N +++ +
Sbjct 147 RLLVYEFMTRGSLENHLFRRGTFYQPLSWNTRVRMALGAARGLAFLHNAQPQVIYRDFKA 206
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVE-RI----PWLAPECLPGGANSL 791
NILL ++ KLSD G+ G + V R+ + APE L G L
Sbjct 207 SNILL-------DSNYNAKLSDFGLARDGPMGDNSHVSTRVMGTQGYAAPEYLATG--HL 257
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH-------FYQRQHRLPEPSCPQL--- 841
S D + FG LLE+ G + P + + + + RL P+L
Sbjct 258 SVKSDVYSFGVVLLEL-LSGRRAIDKNQPVGEHNLVDWARPYLTNKRRLLRVMDPRLQGQ 316
Query 842 ---------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
A L C++ + RP+ I++ + L A NP
Sbjct 317 YSLTRALKIAVLALDCISIDAKSRPTMNEIVKTMEELHIQKEASKEQQNP 366
>sp|A7E3S4|RAF1_BOVIN RAF proto-oncogene serine/threonine-protein
kinase OS=Bos taurus OX=9913 GN=RAF1 PE=2 SV=1
Length=648
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 68/200 (34%), Positives = 102/200 (51%), Gaps = 17/200 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+
Sbjct 355 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILL 407
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++
Sbjct 408 FMGY---MTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 464
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076
IHRD+ + N+ L VKIGDFGLA +V + S + W APE ++
Sbjct 465 IHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-ILWMAPEVIRMQDNN 523
Query 1077 KFYYASDVWSFGVTLYELLT 1096
F + SDV+S+G+ LYEL+T
Sbjct 524 PFSFQSDVYSYGIVLYELMT 543
Score = 64.3 bits (155), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 71/286 (25%), Positives = 127/286 (44%), Gaps = 32/286 (11%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688
G+ G +LKV+DP+ AF +++ + H ++ G + +N+ +VT+
Sbjct 366 GKWHGDVAVKILKVVDPTPEQFQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 422
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ E L L + M + +A+Q A + YL KN++H ++ NI L
Sbjct 423 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF-----LH 477
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANS-LSTAMDKWGFG 801
EG + +K+ D G+ G+ E+ I W+APE + N+ S D + +G
Sbjct 478 EGLT--VKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDNNPFSFQSDVYSYG 535
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854
L E+ GE P + ++ F R + P+ S CP+ + L + C+
Sbjct 536 IVLYEL-MTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKE 594
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+RP F IL + LQ H+L + + AS+P++ + + I
Sbjct 595 ERPLFPQILSSIELLQ-HSLPKI-----NRSASEPSLHRAAHTEDI 634
>sp|Q54TA1|DRKC_DICDI Probable serine/threonine-protein kinase
drkC OS=Dictyostelium discoideum OX=44689 GN=drkC PE=3 SV=1
Length=749
Score = 100 bits (250), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 76/249 (31%), Positives = 118/249 (47%), Gaps = 23/249 (9%)
Query 924 GEMVAVKALK--ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
G +VA+K K + + QE I+ L H +I ++ G C + E + +VMEY+
Sbjct 512 GIIVAIKKAKLLNEDDEDFLNELAQEATIMSQLRHPNICQFLGTCNNPPE--ILIVMEYM 569
Query 982 PLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDNDRLV 1037
PLGSL L P S+ ++ A I +GM YLH IHRDL + N+L+D V
Sbjct 570 PLGSLYRILHDPSISLDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDEHYRV 629
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
KI DFGL+ + + +P W APE L+ + +DV+SF + L+E++T
Sbjct 630 KISDFGLSTRFKKHLDKKTAMTPVGTPC-WTAPEVLRNDPYTEKADVFSFAIVLWEIVTR 688
Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157
D Q PT F +I + Q ++ R P + L+ CW +
Sbjct 689 EDPYQGMPT-FQIVISVGQHKL-------------RPIVPPQVSAPFTRLITECWSEDPQ 734
Query 1158 FRPTFENLI 1166
RP+F+ ++
Sbjct 735 QRPSFQEIV 743
Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 61/238 (26%), Positives = 102/238 (43%), Gaps = 25/238 (11%)
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
K+L+ D + A++MSQ+ H ++ G C PE ++V EY+ G L L
Sbjct 521 KLLNEDDEDFLNELAQEATIMSQLRHPNICQFLGTCNNPPEILIVMEYMPLGSLYRILHD 580
Query 702 ERGHVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ +A +A ++YL + ++H ++ N+L+ +K+SD
Sbjct 581 PSISLDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDE-------HYRVKISD 633
Query 760 PGVG------LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ L + V W APE L + + D + F L EI E
Sbjct 634 FGLSTRFKKHLDKKTAMTPVGTPCWTAPEVLRN--DPYTEKADVFSFAIVLWEIV-TRED 690
Query 814 PLQSRSPSEKEHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
P Q P+ + QH+L P+ S P L ++C + +P QRPSF+ I++ L
Sbjct 691 PYQGM-PTFQIVISVGQHKLRPIVPPQVSAP-FTRLITECWSEDPQQRPSFQEIVKRL 746
>sp|P23437|CDK2_XENLA Cyclin-dependent kinase 2 OS=Xenopus laevis
OX=8355 GN=cdk2 PE=1 SV=3
Length=297
Score = 96.3 bits (238), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 70/207 (34%), Positives = 106/207 (51%), Gaps = 19/207 (9%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955
+K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ L
Sbjct 4 FQKVEKIGEGTYGVV----YKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELN 59
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYV--PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013
H +I+K E L LV E++ L D I LA + + Q+ +G+A+
Sbjct 60 HPNIVKLLDVI--HTENKLYLVFEFLNQDLKKFMDGSNISGISLALVKSYLFQLLQGLAF 117
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070
H+ +HRDL +N+L+++D +K+ DFGLA+A VP + V WY AP
Sbjct 118 CHSHRVLHRDLKPQNLLINSDGAIKLADFGLARAFGVPVRTFTHEV------VTLWYRAP 171
Query 1071 ECLKEYKFY-YASDVWSFGVTLYELLT 1096
E L KFY A D+WS G E++T
Sbjct 172 EILLGCKFYSTAVDIWSLGCIFAEMIT 198
>sp|Q9SZ67|WRK19_ARATH Probable WRKY transcription factor 19 OS=Arabidopsis
thaliana OX=3702 GN=WRKY19 PE=1 SV=1
Length=1895
Score = 101 bits (252), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 84/274 (31%), Positives = 134/274 (49%), Gaps = 43/274 (16%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEID----ILRTLYHE 957
LG G G V Y+ + G+ A K + D G Q W Q+++ +L L H+
Sbjct 1632 LGRGSLGSV----YEGIS-ADGDFFAFKEVSLLDQGSQAHE-WIQQVEGGIALLSQLQHQ 1685
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+I++Y+G +D E +L + +E V GSLR R+ +G + + L+ +QI +G+ YLH +
Sbjct 1686 NIVRYRGTTKD--ESNLYIFLELVTQGSLRKLYQRNQLGDSVVSLYTRQILDGLKYLHDK 1743
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-WYAPECL--- 1073
+IHR++ NVL+D + VK+ DFGLAK + +R +P + W APE +
Sbjct 1744 GFIHRNIKCANVLVDANGTVKLADFGLAKVM----SLWR------TPYWNWMAPEVILNP 1793
Query 1074 KEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
K+Y Y +D+WS G T+ E+LT P LE IG A + +L ++
Sbjct 1794 KDYDGYGTPADIWSLGCTVLEMLTG-----QIPYSDLE-IGTALYNIGTGKLPKI----- 1842
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
PD + + C + RPT L+
Sbjct 1843 ----PDILSLDARDFILTCLKVNPEERPTAAELL 1872
Score = 52.4 bits (124), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 54/213 (25%), Positives = 89/213 (42%), Gaps = 24/213 (11%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQL 718
+L+SQ+ H ++ G + E V G L ++ R + G ++ + +Q+
Sbjct 1677 ALLSQLQHQNIVRYRGTTKDESNLYIFLELVTQGSLRKLYQRNQLGDSVVS---LYTRQI 1733
Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPW 778
L YL +K +H N+ N+L+ A GT +KL+D GL + R W
Sbjct 1734 LDGLKYLHDKGFIHRNIKCANVLVD----ANGT---VKLAD--FGLAKVMSLWRTPYWNW 1784
Query 779 LAPECL--PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836
+APE + P + T D W G T+LE+ G+ P S E P
Sbjct 1785 MAPEVILNPKDYDGYGTPADIWSLGCTVLEM-LTGQIPY---SDLEIGTALYNIGTGKLP 1840
Query 837 SCPQLATLTSQ-----CLTYEPTQRPSFRTILR 864
P + +L ++ CL P +RP+ +L
Sbjct 1841 KIPDILSLDARDFILTCLKVNPEERPTAAELLN 1873
>sp|Q6GPK9|TAOK2_XENLA Serine/threonine-protein kinase TAO2 OS=Xenopus
laevis OX=8355 GN=taok2 PE=2 SV=1
Length=1025
Score = 100 bits (250), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 81/236 (34%), Positives = 119/236 (50%), Gaps = 32/236 (14%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956
+R++G G FG V + D N+ E+VA+K + + G Q W+ +E+ L+ L H
Sbjct 31 LREIGHGSFGAV-YFARDIRNN---EVVAIKKM-SYSGKQSNEKWQDIIKEVKFLQKLRH 85
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014
+ I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL
Sbjct 86 PNTIEYKGCY--LREHTAWLVMEYC-LGSASDLLEVHKKPLQEMEIAAITHGALQGLAYL 142
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071
H + IHRD+ A N+LL LVK+GDFG A + + + +P +W APE
Sbjct 143 HNHNMIHRDVKAGNILLTEPGLVKLGDFGSASIMAPANSFV------GTP-YWMAPEVIL 195
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP----TKFLELIGIAQGQMTVLR 1123
+ E ++ DVWS G+T EL + + PP L IAQ + VL+
Sbjct 196 AMDEGQYDGKVDVWSLGITSIEL-----AERKPPLFNMNAMSALYHIAQNESPVLQ 246
Score = 41.2 bits (95), Expect = 0.066, Method: Compositional matrix adjust.
Identities = 46/184 (25%), Positives = 66/184 (36%), Gaps = 12/184 (7%)
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781
L+YL N N++H +V NILL GL +KL D G V W+AP
Sbjct 139 LAYLHNHNMIHRDVKAGNILLTEPGL-------VKLGDFGSASIMAPANSFVGTPYWMAP 191
Query 782 EC-LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--C 838
E L +D W G T +E+ + S H Q + + + +
Sbjct 192 EVILAMDEGQYDGKVDVWSLGITSIELAERKPPLFNMNAMSALYHIAQNESPVLQSNHWS 251
Query 839 PQLATLTSQCLTYEPTQRPSFRTIL--RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896
CL P RP+ +L R L R +P + L + R
Sbjct 252 EYFRNFVDSCLQKIPQDRPTSDMLLKHRFLQRERPQTVIMELIQRTKDAVRELDNLQYRK 311
Query 897 LKKI 900
+KKI
Sbjct 312 MKKI 315
>sp|O61125|STK4_DICDI Serine/threonine-protein kinase 4 homolog
A OS=Dictyostelium discoideum OX=44689 GN=krsA PE=1 SV=1
Length=461
Score = 99.0 bits (245), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 71/279 (25%), Positives = 131/279 (47%), Gaps = 33/279 (12%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+++ + LGEG +G V Y N TG +VA+K + D ++EI ++
Sbjct 17 EKFFTIVEKLGEGSYGSV----YKAINISTGIVVAIKKVSVD---NDLEDMEKEISFMKQ 69
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGM 1011
+I+ Y + E + +VME+ GS+ D + L+ Q+ + ++ + +G+
Sbjct 70 CKSPYIVTYYASFRKENE--VWIVMEHCGAGSVCDAMKITDKTLSEDQIAVVSRDVLQGL 127
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
AYLH+ IHRD+ A N+L+++ K+ DFG++ + + R+ FW APE
Sbjct 128 AYLHSVRKIHRDIKAGNILMNHKGESKLADFGVSGQLSDTMAK---RQTVIGTPFWMAPE 184
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
++E + Y +D+WS+G+T E+ ++S P F + +R+ ++
Sbjct 185 VIQEIGYDYKADIWSYGITCIEM------AESKPPLF---------NVHPMRVIFMIPNP 229
Query 1132 ER----LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
R L P+K E + C + RP+ E L+
Sbjct 230 SRPPPKLTEPEKWSPEFNDFLAKCLTRKPELRPSAEELL 268
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 34/180 (19%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSR 769
VV++ + L+YL + +H ++ NIL+ G + KL+D GV +++
Sbjct 118 VVSRDVLQGLAYLHSVRKIHRDIKAGNILMNHKGES-------KLADFGVSGQLSDTMAK 170
Query 770 EERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
+ V P W+APE + D W +G T +E+ +S+ P H +
Sbjct 171 RQTVIGTPFWMAPEVIQEIGYDYKA--DIWSYGITCIEMA-------ESKPPLFNVHPMR 221
Query 829 RQHRLPEPS------------CPQLATLTSQCLTYEPTQRPSFRTILRD--LTRLQPHNL 874
+P PS P+ ++CLT +P RPS +L+ +T+ + H+L
Sbjct 222 VIFMIPNPSRPPPKLTEPEKWSPEFNDFLAKCLTRKPELRPSAEELLKHPFITKAKSHSL 281
>sp|P79749|PGFRB_TAKRU Platelet-derived growth factor receptor
beta OS=Takifugu rubripes OX=31033 GN=pdgfrb PE=3 SV=1
Length=1048
Score = 100 bits (250), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 70/222 (32%), Positives = 105/222 (47%), Gaps = 29/222 (13%)
Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
++QG + LV+ P + D LL F+ Q+ +GM +L +++ +HRDLAA
Sbjct 776 QEQGGGRVDLVISDSPALTYDD-----------LLGFSYQVAKGMEFLASKNCVHRDLAA 824
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RNVL+ +LVKI DFGLA+ + Y + P+ W APE + + SDVWS
Sbjct 825 RNVLICEGKLVKICDFGLARDIMHDSNYIS-KGSTFLPLKWMAPESIFHNLYTTLSDVWS 883
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
+G+ L+E+ T + P EL L+RG R+ +P EVY
Sbjct 884 YGILLWEIFT-LGGTPYPDLPMNEL------------FYSPLKRGYRMAKPAHASDEVYE 930
Query 1147 LMKNCWETEASFRPTFENLI----PILKTVHEKYQGQAPSVF 1184
+MK CW+ RP F L+ +L ++K Q F
Sbjct 931 IMKRCWDETFEKRPDFSFLVHCVGDMLTDSYKKKYSQVNETF 972
Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 43/174 (25%), Positives = 77/174 (44%), Gaps = 30/174 (17%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L +KN VH ++ RN+L + EG +K+ D G+ + + +
Sbjct 804 QVAKGMEFLASKNCVHRDLAARNVL-----ICEGK--LVKICDFGLARDIMHDSNYISKG 856
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--- 827
+ W+APE + N +T D W +G L EI G P +E FY
Sbjct 857 STFLPLKWMAPESI--FHNLYTTLSDVWSYGILLWEIFTLGGTPYPDLPMNEL--FYSPL 912
Query 828 QRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
+R +R+ +P + ++ + +C +RP F ++ H + D+LT
Sbjct 913 KRGYRMAKPAHASDEVYEIMKRCWDETFEKRPDFSFLV--------HCVGDMLT 958
Score = 40.4 bits (93), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 35/108 (32%), Positives = 45/108 (42%), Gaps = 4/108 (4%)
Query 901 RDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY-HEH 958
R LG G FG+V + ++ + VAVK LKA E+ I+ L H +
Sbjct 600 RTLGSGAFGRVVEATAHGLSHSQSSIKVAVKMLKATARRSETQALMSELKIMSHLGPHLN 659
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006
I+ C G L LV EY G L DYL R+ Q L Q
Sbjct 660 IVNLLAACTKHG--PLYLVTEYCRYGDLVDYLHRNKHTFLQYYLDKNQ 705
>sp|Q9Z2W1|STK25_MOUSE Serine/threonine-protein kinase 25 OS=Mus
musculus OX=10090 GN=Stk25 PE=1 SV=2
Length=426
Score = 98.2 bits (243), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 77/274 (28%), Positives = 125/274 (46%), Gaps = 36/274 (13%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
K+ +G+G FG+V Y ++ T E+VA+K + + +QEI +L +
Sbjct 22 KLDRIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPY 77
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I +Y G + L ++MEY+ GS D L + + ++I +G+ YLH++
Sbjct 78 ITRYFGSYLKSTK--LWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSER 135
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ A NVLL VK+ DFG+A + + R FW APE +K+ +
Sbjct 136 KIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQ---IKRNTFVGTPFWMAPEVIKQSAY 192
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+ +D+WS G+T EL + PP L M VL L +P+ +
Sbjct 193 DFKADIWSLGITAIEL-----AKGEPPNSDLH-------PMRVLFL---------IPKNN 231
Query 1139 KCPCEVYH------LMKNCWETEASFRPTFENLI 1166
E +H ++ C + FRPT + L+
Sbjct 232 PPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELL 265
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 64/298 (21%), Positives = 121/298 (41%), Gaps = 60/298 (20%)
Query 583 RVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
RVD +E+ T+L +G+G+ VY+G +D+ V V +
Sbjct 13 RVDPEELFTKLDRIGKGSFGEVYKG--------------IDNHTKEV----------VAI 48
Query 642 KVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWL 699
K++D D + +++SQ ++ G ++ + ++ EY+ G LD+
Sbjct 49 KIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLL- 107
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ G + + + +++ L YL ++ +H ++ N+LL+ G +KL+D
Sbjct 108 --KPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQG-------DVKLAD 158
Query 760 PGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
GV G L+ R V W+APE + A D W G T +E+
Sbjct 159 FGVA-GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKA--DIWSLGITAIELA------ 209
Query 815 LQSRSPSEKEHFYQRQHRLPEPSCPQL--------ATLTSQCLTYEPTQRPSFRTILR 864
+ P+ H + +P+ + P L CL +P RP+ + +L+
Sbjct 210 -KGEPPNSDLHPMRVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLK 266
>sp|Q5UQG7|YR818_MIMIV Putative serine/threonine-protein kinase/receptor
R818 OS=Acanthamoeba polyphaga mimivirus OX=212035
GN=MIMI_R818 PE=3 SV=1
Length=1651
Score = 101 bits (251), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 80/287 (28%), Positives = 132/287 (46%), Gaps = 26/287 (9%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDI 950
FH+ L + LG G G+V + G VAVK L ++ +KQEI
Sbjct 790 FHE--LDFMESLGSGGSGEVFKAMWK------GTEVAVKKLVNSNITKDAERNFKQEIHR 841
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL---FAQQI 1007
+ +L H +++ + ++ +VME++ LGSL D L + +L A Q
Sbjct 842 MTSLRHPNVVLFMAASTR--PPNMCIVMEFMSLGSLYDLLGNELVTEIPPVLRIRIAYQA 899
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+GM +LH+ +HRDL + N+LLD+ VK+ DFGL K +ED + W
Sbjct 900 AKGMHFLHSSDIVHRDLKSLNLLLDSKWNVKVSDFGLTKIKDNNKGKSSTKEDSVCSIQW 959
Query 1068 YAPECLKEYK--FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
APE L E + Y +DV+SFG+ ++EL+ T+ IG++ + V +
Sbjct 960 TAPEVLSEKQDIDYILADVYSFGIIMWELM----------TRLRPYIGLSPAAIAVAVIR 1009
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ L + + + L+ CW + RP+F ++ L T+
Sbjct 1010 DNLRPEIQEEDINLMSSDYVELVNICWHKDTMIRPSFLEIMTKLSTL 1056
Score = 99.0 bits (245), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 80/269 (30%), Positives = 123/269 (46%), Gaps = 31/269 (12%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G +G V++ + N VAVK +K + ++ EI L L H HI
Sbjct 1398 KQIGVGSYGIVNMGKWKNIN------VAVKKFVKQKIDEKQMLEFRAEIAFLSQLRHPHI 1451
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018
I G C + ++ +V E++ GSLR+ + + Q G+ YLH
Sbjct 1452 ILMIGACLKR--PNICIVTEFMGNGSLRNVIKTTKPEWKLKIKMLYQTALGIGYLHNSDP 1509
Query 1019 -YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ N+L+D+ VKI DFG A+ E R +P W APE ++ K
Sbjct 1510 IIIHRDIKPSNILVDDSMNVKIADFGFARIKEENSVMTRC----GTPC-WTAPEIIRGEK 1564
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ DV+SFG+ ++E+LT C S F+++ M +L G R P
Sbjct 1565 YTEKVDVFSFGIVMWEVLT-CKEPFS-GCNFMKV------SMDIL-------EGARPQIP 1609
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
CP + LMK CW + RP+ E++I
Sbjct 1610 SDCPIDFTKLMKQCWHAKPDKRPSMEDVI 1638
Score = 59.7 bits (143), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 55/231 (24%), Positives = 99/231 (43%), Gaps = 34/231 (15%)
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
L F + +SQ+ H H+ + G C++ P +VTE++ +G L ++ + + KM
Sbjct 1434 LEFRAEIAFLSQLRHPHIILMIGACLKRPNICIVTEFMGNGSLRNVIKTTKPEWKLKIKM 1493
Query 713 VVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ Q A + YL N + ++H ++ NIL+ S +K++D G + E
Sbjct 1494 L--YQTALGIGYLHNSDPIIIHRDIKPSNILV-------DDSMNVKIAD--FGFARIKEE 1542
Query 771 ERVER---IP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
V P W APE + G + +D + FG + E+ L + P +F
Sbjct 1543 NSVMTRCGTPCWTAPEIIRG--EKYTEKVDVFSFGIVMWEV-------LTCKEPFSGCNF 1593
Query 827 YQRQHRLPEPSCPQL--------ATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + E + PQ+ L QC +P +RPS ++ L +
Sbjct 1594 MKVSMDILEGARPQIPSDCPIDFTKLMKQCWHAKPDKRPSMEDVIMGLNDM 1644
Score = 53.9 bits (128), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 56/246 (23%), Positives = 98/246 (40%), Gaps = 11/246 (4%)
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
+G E+ V V D F + M+ + H ++ R P +V E++
Sbjct 813 KGTEVAVKKLVNSNITKDAERNFKQEIHRMTSLRHPNVVLFMAASTRPPNMCIVMEFMSL 872
Query 693 GPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEG 750
G L L E +P ++ +A Q A + +L + ++VH ++ N+LL ++ +
Sbjct 873 GSLYDLLGNELVTEIPPVLRIRIAYQAAKGMHFLHSSDIVHRDLKSLNLLLDSKWNVKVS 932
Query 751 TSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K+ D G + ++E+ V I W APE L + D + FG + E+
Sbjct 933 DFGLTKIKDNNKGKSS-TKEDSVCSIQWTAPEVLSEKQDIDYILADVYSFGIIMWEL-MT 990
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ-------CLTYEPTQRPSFRTIL 863
P SP+ R + PE + ++S C + RPSF I+
Sbjct 991 RLRPYIGLSPAAIAVAVIRDNLRPEIQEEDINLMSSDYVELVNICWHKDTMIRPSFLEIM 1050
Query 864 RDLTRL 869
L+ L
Sbjct 1051 TKLSTL 1056
>sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo
sapiens OX=9606 GN=BRAF PE=1 SV=4
Length=766
Score = 100 bits (249), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 78/274 (28%), Positives = 123/274 (45%), Gaps = 35/274 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK L PQ +K E+ +LR H +I+
Sbjct 463 IGSGSFGTV----YKGKWHGD---VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 515
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + L +V ++ SL +L + +L+ A+Q +GM YLHA+
Sbjct 516 FMGYST---KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSI 572
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076
IHRDL + N+ L D VKIGDFGLA ++ + S + W APE ++ +
Sbjct 573 IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGS-ILWMAPEVIRMQDKN 631
Query 1077 KFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + SDV++FG+ LYEL+T + + + F+ G ++ +R
Sbjct 632 PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVR--------- 682
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
CP + LM C + + RP F ++
Sbjct 683 -----SNCPKAMKRLMAECLKKKRDERPLFPQIL 711
Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 60/254 (24%), Positives = 106/254 (42%), Gaps = 24/254 (9%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G+ G +L V P+ + AF ++ + H ++ G + P+ +VT++
Sbjct 474 GKWHGDVAVKMLNVTAPTPQQLQ-AFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQW 531
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
E L L M + +A+Q A + YL K+++H ++ NI L
Sbjct 532 CEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE----- 586
Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802
+K+ D G+ G+ E+ I W+APE + N S D + FG
Sbjct 587 --DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGI 644
Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855
L E+ G+ P + + ++ F R + P+ S CP+ + L ++CL + +
Sbjct 645 VLYEL-MTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDE 703
Query 856 RPSFRTILRDLTRL 869
RP F IL + L
Sbjct 704 RPLFPQILASIELL 717
>sp|O49839|PBL2_ARATH Probable serine/threonine-protein kinase
PBL2 OS=Arabidopsis thaliana OX=3702 GN=PBL2 PE=1 SV=1
Length=426
Score = 98.2 bits (243), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 78/207 (38%), Positives = 108/207 (52%), Gaps = 20/207 (10%)
Query 903 LGEGHFGKVSLYCYDPTN-----DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LGEG FG V D T+ G+G +VAVK LK + G Q W E++ L L H
Sbjct 92 LGEGGFGCVFKGWIDQTSLTASRPGSGIVVAVKQLKPE-GFQGHKEWLTEVNYLGQLSHP 150
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI------CEGM 1011
+++ G C +GE L LV E++P GSL ++L R AQ L +A ++ +G+
Sbjct 151 NLVLLVGYCA-EGENRL-LVYEFMPKGSLENHLFRRG---AQPLTWAIRMKVAVGAAKGL 205
Query 1012 AYLH--AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+LH I+RD A N+LLD D K+ DFGLAKA P G + V + A
Sbjct 206 TFLHEAKSQVIYRDFKAANILLDADFNAKLSDFGLAKAGPTGDNTH-VSTKVIGTHGYAA 264
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096
PE + + SDV+SFGV L EL++
Sbjct 265 PEYVATGRLTAKSDVYSFGVVLLELIS 291
Score = 56.2 bits (134), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 78/327 (24%), Positives = 127/327 (39%), Gaps = 57/327 (17%)
Query 575 NLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
NL +F+ + K Q + LG+G V++G + D+ L R
Sbjct 70 NLKAFTFNELKNATKNFRQDNLLGEGGFGCVFKGWI--------------DQTSLTASRP 115
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
G + V +K L P + + + Q+SH +L + G C G ++V E++
Sbjct 116 -GSGIVVAVKQLKPEGFQGHKEWLTEVNYLGQLSHPNLVLLVGYCAEGENRLLVYEFMPK 174
Query 693 GPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLA 748
G L+ L R RG P+ W +M VA A L++L +++ + NILL
Sbjct 175 GSLENHLFR-RGAQPLTWAIRMKVAVGAAKGLTFLHEAKSQVIYRDFKAANILL------ 227
Query 749 EGTSPF-IKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFG 801
+ F KLSD G+ + + + + APE + G L+ D + FG
Sbjct 228 --DADFNAKLSDFGLAKAGPTGDNTHVSTKVIGTHGYAAPEYVATG--RLTAKSDVYSFG 283
Query 802 ATLLEICFDGEAPLQSRSPSE--------------KEHFYQRQHRL----PEPSCPQLAT 843
LLE+ A S +E ++ F +L P+ A
Sbjct 284 VVLLELISGRRAMDNSNGGNEYSLVDWATPYLGDKRKLFRIMDTKLGGQYPQKGAFTAAN 343
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQ 870
L QCL + RP +L L +L+
Sbjct 344 LALQCLNPDAKLRPKMSEVLVTLEQLE 370
>sp|Q6QNF3|PGFRB_CANLF Platelet-derived growth factor receptor
beta OS=Canis lupus familiaris OX=9615 GN=PDGFRB PE=2 SV=1
Length=1103
Score = 100 bits (250), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 58/168 (35%), Positives = 87/168 (52%), Gaps = 14/168 (8%)
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ L+ F+ Q+ GM +L +++ +HRDLAARNVL+ +LVKI DFGLA+ + Y
Sbjct 798 LSYTDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNY 857
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ P+ W APE + + SDVWSFG+ L+E+ T T + EL
Sbjct 858 IS-KGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGG------TPYPELPMN 910
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
Q ++RG R+ +P E+Y +M+ CWE + RP F
Sbjct 911 EQ-------FYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPF 951
Score = 49.3 bits (116), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 42/155 (27%), Positives = 71/155 (46%), Gaps = 24/155 (15%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A+ + +L +KN VH ++ RN+L + EG +K+ D G+ + + +
Sbjct 809 QVANGMEFLASKNCVHRDLAARNVL-----ICEGK--LVKICDFGLARDIMRDSNYISKG 861
Query 776 -----IPWLAPECLPGGANSLSTAM-DKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-- 827
+ W+APE + NSL T + D W FG L EI G P E FY
Sbjct 862 STFLPLKWMAPESI---FNSLYTTLSDVWSFGILLWEIFTLGGTPYPEL--PMNEQFYNA 916
Query 828 -QRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSF 859
+R +R+ +P + ++ + +C + RP F
Sbjct 917 IKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPF 951
Score = 39.7 bits (91), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 4/102 (4%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLY-HEH 958
R LG G FG+V + M VAVK LK+ + E+ I+ L H +
Sbjct 604 RTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLN 663
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL 1000
++ G C G + ++ EY G L DYL R+ QL
Sbjct 664 VVNLLGACTKGG--PIYIITEYCRYGDLVDYLHRNKHTFLQL 703
>sp|Q9XI96|PERK7_ARATH Proline-rich receptor-like protein kinase
PERK7 OS=Arabidopsis thaliana OX=3702 GN=PERK7 PE=2 SV=1
Length=699
Score = 100 bits (248), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 74/207 (36%), Positives = 106/207 (51%), Gaps = 17/207 (8%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
K R LG+G FG V G+ +AVK+LKA G R ++ E++I+ ++H
Sbjct 336 FSKDRLLGQGGFGYVHKGILP-----NGKEIAVKSLKAGSGQGERE-FQAEVEIISRVHH 389
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAY 1013
H++ G C + G + L LV E++P +L +L S + L A +G+AY
Sbjct 390 RHLVSLVGYCSNAGGQRL-LVYEFLPNDTLEFHLHGKSGTVMDWPTRLKIALGSAKGLAY 448
Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-A 1069
LH IHRD+ A N+LLD++ K+ DFGLAK + + + R G F Y A
Sbjct 449 LHEDCHPKIIHRDIKASNILLDHNFEAKVADFGLAKLSQDNNTHVSTRVMG---TFGYLA 505
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096
PE K SDV+SFGV L EL+T
Sbjct 506 PEYASSGKLTEKSDVFSFGVMLLELIT 532
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 48/174 (28%), Positives = 77/174 (44%), Gaps = 26/174 (15%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDVWLRRERGHVPMAW--K 711
F ++S+V H HL + G C G + ++V E++ + L+ L + G V M W +
Sbjct 377 FQAEVEIISRVHHRHLVSLVGYCSNAGGQRLLVYEFLPNDTLEFHLHGKSGTV-MDWPTR 435
Query 712 MVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ +A A L+YL ++H ++ NILL A K++D GL LS
Sbjct 436 LKIALGSAKGLAYLHEDCHPKIIHRDIKASNILLDHNFEA-------KVAD--FGLAKLS 486
Query 769 REERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
++ +LAPE G L+ D + FG LLE+ G P+
Sbjct 487 QDNNTHVSTRVMGTFGYLAPEYASSG--KLTEKSDVFSFGVMLLEL-ITGRGPV 537
>sp|P35916|VGFR3_HUMAN Vascular endothelial growth factor receptor
3 OS=Homo sapiens OX=9606 GN=FLT4 PE=1 SV=3
Length=1363
Score = 100 bits (250), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 58/175 (33%), Positives = 90/175 (51%), Gaps = 14/175 (8%)
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ + L+ ++ Q+ GM +L ++ IHRDLAARN+LL +VKI DFGLA+ + + +Y
Sbjct 1009 LTMEDLVCYSFQVARGMEFLASRKCIHRDLAARNILLSESDVVKICDFGLARDIYKDPDY 1068
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
R + P+ W APE + + + SDVWSFGV L+E+ + +S P + E
Sbjct 1069 VR-KGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFS-LGASPYPGVQINE---- 1122
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ L G R+ P+ + +M NCW + RP F L+ IL
Sbjct 1123 --------EFCQRLRDGTRMRAPELATPAIRRIMLNCWSGDPKARPAFSELVEIL 1169
Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 43/164 (26%), Positives = 73/164 (45%), Gaps = 22/164 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A + +L ++ +H ++ RNILL+ S +K+ D G+ + V +
Sbjct 1020 QVARGMEFLASRKCIHRDLAARNILLSE-------SDVVKICDFGLARDIYKDPDYVRKG 1072
Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
+ W+APE + +T D W FG L EI G +P +E+ F QR
Sbjct 1073 SARLPLKWMAPESIFDKV--YTTQSDVWSFGVLLWEIFSLGASPYPGVQINEE--FCQRL 1128
Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ R PE + P + + C + +P RP+F ++ L L
Sbjct 1129 RDGTRMRAPELATPAIRRIMLNCWSGDPKARPAFSELVEILGDL 1172
>sp|Q9SY91|PBL15_ARATH Probable serine/threonine-protein kinase
PBL15 OS=Arabidopsis thaliana OX=3702 GN=PBL15 PE=1 SV=1
Length=424
Score = 98.2 bits (243), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 90/256 (35%), Positives = 122/256 (48%), Gaps = 24/256 (9%)
Query 857 PSFRTI-LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD-------LGEGHF 908
PSFR + DL+R + + L + +D F LK I LGEG F
Sbjct 54 PSFRRLSFADLSRSSSARINEDLA---QTLGADLVDFQMCELKMITQSFSGNYLLGEGGF 110
Query 909 GKV-SLYCYDPTNDG-TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG-C 965
GKV Y D + VAVK L + HR W E+ L L H +++K G C
Sbjct 111 GKVYKGYVDDYLRQSLKAQPVAVKLLDIEGLQGHRE-WLSEVIFLGQLKHPNLVKLIGYC 169
Query 966 CEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQH--YI 1020
CE E+ L+ E++P GSL ++L R S+ A L A +G+A+LH I
Sbjct 170 CE---EEERVLIYEFMPRGSLENHLFRRISLSLPWATRLKIAVAAAKGLAFLHDLESPII 226
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
+RD N+LLD+D K+ DFGLAK PEG + + V + APE +
Sbjct 227 YRDFKTSNILLDSDFTAKLSDFGLAKMGPEGSKSH-VTTRVMGTYGYAAPEYVSTGHLTT 285
Query 1081 ASDVWSFGVTLYELLT 1096
SDV+S+GV L ELLT
Sbjct 286 KSDVYSYGVVLLELLT 301
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 79/332 (24%), Positives = 131/332 (39%), Gaps = 64/332 (19%)
Query 572 RTLNLSQLSFHRVDQKEITQLSH----LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
+TL + F + K ITQ LG+G VY+G + +D L
Sbjct 78 QTLGADLVDFQMCELKMITQSFSGNYLLGEGGFGKVYKGYV---------------DDYL 122
Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
R + V +K+LD + + Q+ H +L + G C E +++
Sbjct 123 ---RQSLKAQPVAVKLLDIEGLQGHREWLSEVIFLGQLKHPNLVKLIGYCCEEEERVLIY 179
Query 688 EYVEHGPLDVWL-RRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLAR 744
E++ G L+ L RR +P A ++ +A A L++L + +++ + NILL
Sbjct 180 EFMPRGSLENHLFRRISLSLPWATRLKIAVAAAKGLAFLHDLESPIIYRDFKTSNILL-- 237
Query 745 LGLAEGTSPFI-KLSDPGVGLGAL----SREERVERI----PWLAPECLPGGANSLSTAM 795
S F KLSD GL + S+ R+ + APE + G L+T
Sbjct 238 ------DSDFTAKLSD--FGLAKMGPEGSKSHVTTRVMGTYGYAAPEYVSTG--HLTTKS 287
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEK------EHFYQRQHRLPEPSCPQLA------- 842
D + +G LLE+ A +SR +++ + + RL P+LA
Sbjct 288 DVYSYGVVLLELLTGRRATEKSRPKNQQNIIDWSKPYLTSSRRLRCVMDPRLAGQYSVKA 347
Query 843 -----TLTSQCLTYEPTQRPSFRTILRDLTRL 869
L QC++ P RP ++ L L
Sbjct 348 AKDTALLALQCVSPNPKDRPKMLAVVEALESL 379
>sp|O43283|M3K13_HUMAN Mitogen-activated protein kinase kinase
kinase 13 OS=Homo sapiens OX=9606 GN=MAP3K13 PE=1 SV=1
Length=966
Score = 100 bits (249), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 83/273 (30%), Positives = 120/273 (44%), Gaps = 39/273 (14%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI--LRTL 954
+ +++ LG G G V L + E VA+K ++ + E DI LR L
Sbjct 168 ISELQWLGSGAQGAVFLGKF------RAEEVAIKKVRE----------QNETDIKHLRKL 211
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAY 1013
H +II +KG C ++MEY G L + L +LL+ ++ I GM Y
Sbjct 212 KHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNY 269
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
LH IHRDL + NVL+ + VKI DFG +K + + + V W APE +
Sbjct 270 LHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDK----STKMSFAGTVAWMAPEVI 325
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ D+WSFGV L+ELLT P K ++ I G +
Sbjct 326 RNEPVSEKVDIWSFGVVLWELLT-----GEIPYKDVDSSAIIWG---------VGSNSLH 371
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
LP P CP LMK W+++ RP+F +
Sbjct 372 LPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTL 404
Score = 65.1 bits (157), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 75/308 (24%), Positives = 120/308 (39%), Gaps = 54/308 (18%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+A L Q V +EI++L LG G + V+ G+ R E
Sbjct 146 GKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAEEVA------------ 193
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+ KV + + DI + ++ H ++ GVC + P ++
Sbjct 194 -------------IKKVREQNETDIKH--------LRKLKHPNIIAFKGVCTQAPCYCII 232
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLAR 744
EY HG L LR R P +++V + +AS ++YL ++H ++ N+L+
Sbjct 233 MEYCAHGQLYEVLRAGRKITP---RLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTH 289
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFG 801
+ +K+SD G + ++ + W+APE + +S +D W FG
Sbjct 290 -------TDAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFG 340
Query 802 ATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPS 858
L E+ GE P + S LP PS CP L Q +P RPS
Sbjct 341 VVLWEL-LTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPS 399
Query 859 FRTILRDL 866
FR L L
Sbjct 400 FRQTLMHL 407
>sp|P28028|BRAF_MOUSE Serine/threonine-protein kinase B-raf OS=Mus
musculus OX=10090 GN=Braf PE=1 SV=4
Length=751
Score = 100 bits (248), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 78/274 (28%), Positives = 123/274 (45%), Gaps = 35/274 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK L PQ +K E+ +LR H +I+
Sbjct 448 IGSGSFGTV----YKGKWHGD---VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 500
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + L +V ++ SL +L + +L+ A+Q +GM YLHA+
Sbjct 501 FMGYST---KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSI 557
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076
IHRDL + N+ L D VKIGDFGLA ++ + S + W APE ++ +
Sbjct 558 IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGS-ILWMAPEVIRMQDKN 616
Query 1077 KFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + SDV++FG+ LYEL+T + + + F+ G ++ +R
Sbjct 617 PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVR--------- 667
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
CP + LM C + + RP F ++
Sbjct 668 -----SNCPKAMKRLMAECLKKKRDERPLFPQIL 696
Score = 52.4 bits (124), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 60/254 (24%), Positives = 106/254 (42%), Gaps = 24/254 (9%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G+ G +L V P+ + AF ++ + H ++ G + P+ +VT++
Sbjct 459 GKWHGDVAVKMLNVTAPTPQQLQ-AFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQW 516
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
E L L M + +A+Q A + YL K+++H ++ NI L
Sbjct 517 CEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE----- 571
Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802
+K+ D G+ G+ E+ I W+APE + N S D + FG
Sbjct 572 --DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGI 629
Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855
L E+ G+ P + + ++ F R + P+ S CP+ + L ++CL + +
Sbjct 630 VLYEL-MTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDE 688
Query 856 RPSFRTILRDLTRL 869
RP F IL + L
Sbjct 689 RPLFPQILASIELL 702
>sp|Q04982|BRAF_CHICK Serine/threonine-protein kinase B-raf OS=Gallus
gallus OX=9031 GN=BRAF PE=1 SV=2
Length=766
Score = 100 bits (248), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 78/274 (28%), Positives = 123/274 (45%), Gaps = 35/274 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK L PQ +K E+ +LR H +I+
Sbjct 463 IGSGSFGTV----YKGKWHGD---VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 515
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + L +V ++ SL +L + +L+ A+Q +GM YLHA+
Sbjct 516 FMGYST---KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSI 572
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076
IHRDL + N+ L D VKIGDFGLA ++ + S + W APE ++ +
Sbjct 573 IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGS-ILWMAPEVIRMQDKN 631
Query 1077 KFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + SDV++FG+ LYEL+T + + + F+ G ++ +R
Sbjct 632 PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVR--------- 682
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
CP + LM C + + RP F ++
Sbjct 683 -----SNCPKAMKRLMAECLKKKRDERPLFPQIL 711
Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 60/254 (24%), Positives = 106/254 (42%), Gaps = 24/254 (9%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G+ G +L V P+ + AF ++ + H ++ G + P+ +VT++
Sbjct 474 GKWHGDVAVKMLNVTAPTPQQLQ-AFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQW 531
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
E L L M + +A+Q A + YL K+++H ++ NI L
Sbjct 532 CEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE----- 586
Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802
+K+ D G+ G+ E+ I W+APE + N S D + FG
Sbjct 587 --DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGI 644
Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855
L E+ G+ P + + ++ F R + P+ S CP+ + L ++CL + +
Sbjct 645 VLYEL-MTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDE 703
Query 856 RPSFRTILRDLTRL 869
RP F IL + L
Sbjct 704 RPLFPQILASIELL 717
>sp|Q8T2I8|SEPA_DICDI Serine/threonine-protein kinase sepA OS=Dictyostelium
discoideum OX=44689 GN=sepA PE=2 SV=1
Length=1167
Score = 100 bits (250), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 63/196 (32%), Positives = 102/196 (52%), Gaps = 13/196 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIK 961
+G+G FG V Y + G+ VA+K + P+ + G EID+L+ L H +I+K
Sbjct 24 IGKGGFGTV----YQGLDIEDGDFVAIKQINLTKIPKDQLQGIMNEIDLLKNLNHANIVK 79
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL-LFAQQICEGMAYLHAQHYI 1020
Y + + +L +V+EYV GSL + + L+ ++ +Q+ EG+ YLH Q +
Sbjct 80 YIKYVKTKD--NLYIVLEYVENGSLSGIIKKFGKFPETLVCVYIRQVLEGLVYLHEQGVV 137
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ N+L + +K+ DFG+A + V +P +W APE ++
Sbjct 138 HRDIKGANILTTKEGKIKLADFGVATKFDDTSAAAVV----GTP-YWMAPEIIELNGATT 192
Query 1081 ASDVWSFGVTLYELLT 1096
SD+WS G T+ ELLT
Sbjct 193 KSDIWSVGCTVIELLT 208
Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 56/192 (29%), Positives = 84/192 (44%), Gaps = 16/192 (8%)
Query 678 VRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736
V+ +N+ +V EYVE+G L +++ G P V +Q+ L YL + +VH ++
Sbjct 84 VKTKDNLYIVLEYVENGSLSGIIKK-FGKFPETLVCVYIRQVLEGLVYLHEQGVVHRDIK 142
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTA 794
G NIL + G IKL+D GV S V W+APE + N +T
Sbjct 143 GANILTTKEGK-------IKLADFGVATKFDDTSAAAVVGTPYWMAPEIIE--LNGATTK 193
Query 795 MDKWGFGATLLEICFDGEAPLQS--RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYE 852
D W G T++E+ G P + P+ LPE P L QC +
Sbjct 194 SDIWSVGCTVIEL-LTGSPPYYDLGQMPALFRIVQDDCPPLPEGISPPLKDWLMQCFQKD 252
Query 853 PTQRPSFRTILR 864
P R S + +L+
Sbjct 253 PNLRISAQKLLK 264
>sp|P34908|BRAF_COTJA Serine/threonine-protein kinase B-raf OS=Coturnix
japonica OX=93934 GN=BRAF PE=2 SV=1
Length=807
Score = 100 bits (248), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 78/274 (28%), Positives = 123/274 (45%), Gaps = 35/274 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK L PQ +K E+ +LR H +I+
Sbjct 503 IGSGSFGTV----YKGKWHGD---VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 555
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + L +V ++ SL +L + +L+ A+Q +GM YLHA+
Sbjct 556 FMGYST---KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSI 612
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076
IHRDL + N+ L D VKIGDFGLA ++ + S + W APE ++ +
Sbjct 613 IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGS-ILWMAPEVIRMQDKN 671
Query 1077 KFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + SDV++FG+ LYEL+T + + + F+ G ++ +R
Sbjct 672 PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVR--------- 722
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
CP + LM C + + RP F ++
Sbjct 723 -----SNCPKAMKRLMAECLKKKRDERPLFPQIL 751
Score = 52.0 bits (123), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 60/254 (24%), Positives = 106/254 (42%), Gaps = 24/254 (9%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G+ G +L V P+ + AF ++ + H ++ G + P+ +VT++
Sbjct 514 GKWHGDVAVKMLNVTAPTPQQLQ-AFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQW 571
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
E L L M + +A+Q A + YL K+++H ++ NI L
Sbjct 572 CEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE----- 626
Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802
+K+ D G+ G+ E+ I W+APE + N S D + FG
Sbjct 627 --DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGI 684
Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855
L E+ G+ P + + ++ F R + P+ S CP+ + L ++CL + +
Sbjct 685 VLYEL-MTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDE 743
Query 856 RPSFRTILRDLTRL 869
RP F IL + L
Sbjct 744 RPLFPQILASIELL 757
>sp|Q9C6K9|LRL11_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE
PROTEIN KINASE-like 1.1 OS=Arabidopsis thaliana
OX=3702 GN=LRK10L-1.1 PE=2 SV=1
Length=629
Score = 99.8 bits (247), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 86/293 (29%), Positives = 135/293 (46%), Gaps = 23/293 (8%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
K R LG+G FG V Y DG VAVK L + + + EI+IL L+H
Sbjct 291 FSKDRLLGDGGFGTVY---YGKVRDG--REVAVKRL-YEHNYRRLEQFMNEIEILTRLHH 344
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEG 1010
++++ GC + + L LV E++P G++ D+L + + + L A +
Sbjct 345 KNLVSLYGCTSRRS-RELLLVYEFIPNGTVADHLYGENTPHQGFLTWSMRLSIAIETASA 403
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
+AYLHA IHRD+ N+LLD + VK+ DFGL++ +P + G + P
Sbjct 404 LAYLHASDIIHRDVKTTNILLDRNFGVKVADFGLSRLLPSDVTHVSTAPQGTPG--YVDP 461
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
E + Y SDV+SFGV L EL++ D S+ L + I + Q EL
Sbjct 462 EYHRCYHLTDKSDVYSFGVVLVELISSKPAVDISRCKSEINLSSLAINKIQNHATH--EL 519
Query 1128 LERGERLPRPD---KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
+++ + K V L C + + + RPT E ++ LK + + Q
Sbjct 520 IDQNLGYATNEGVRKMTTMVAELAFQCLQQDNTMRPTMEQVVHELKGIQNEEQ 572
Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 58/248 (23%), Positives = 105/248 (42%), Gaps = 43/248 (17%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDVWLRRE----RGHVPMA 709
F +++++ H +L ++G R E ++V E++ +G + L E +G + +
Sbjct 332 FMNEIEILTRLHHKNLVSLYGCTSRRSRELLLVYEFIPNGTVADHLYGENTPHQGFLTWS 391
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
++ +A + ASAL+YL +++H +V NILL R + +K++D G+ S
Sbjct 392 MRLSIAIETASALAYLHASDIIHRDVKTTNILLDR-------NFGVKVADFGLSRLLPSD 444
Query 770 EERVERIPWLAPECLPGGAN-------SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
V AP+ PG + L+ D + FG L+E+ A SR SE
Sbjct 445 VTHVS----TAPQGTPGYVDPEYHRCYHLTDKSDVYSFGVVLVELISSKPAVDISRCKSE 500
Query 823 --------KEHFYQRQHRLPEPS------------CPQLATLTSQCLTYEPTQRPSFRTI 862
+ H L + + +A L QCL + T RP+ +
Sbjct 501 INLSSLAINKIQNHATHELIDQNLGYATNEGVRKMTTMVAELAFQCLQQDNTMRPTMEQV 560
Query 863 LRDLTRLQ 870
+ +L +Q
Sbjct 561 VHELKGIQ 568
>sp|Q5R8X7|M3K13_PONAB Mitogen-activated protein kinase kinase
kinase 13 OS=Pongo abelii OX=9601 GN=MAP3K13 PE=2 SV=1
Length=966
Score = 100 bits (249), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 83/273 (30%), Positives = 120/273 (44%), Gaps = 39/273 (14%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI--LRTL 954
+ +++ LG G G V L + E VA+K ++ + E DI LR L
Sbjct 168 ISELQWLGSGAQGAVFLGKF------RAEEVAIKKVRE----------QNETDIKHLRKL 211
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAY 1013
H +II +KG C ++MEY G L + L +LL+ ++ I GM Y
Sbjct 212 KHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNY 269
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
LH IHRDL + NVL+ + VKI DFG +K + + + V W APE +
Sbjct 270 LHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDK----STKMSFAGTVAWLAPEVI 325
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ D+WSFGV L+ELLT P K ++ I G +
Sbjct 326 RNEPVSEKVDIWSFGVVLWELLT-----GEIPYKDVDSSAIIWG---------VGSNSLH 371
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
LP P CP LMK W+++ RP+F +
Sbjct 372 LPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTL 404
Score = 65.9 bits (159), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 75/299 (25%), Positives = 118/299 (39%), Gaps = 54/299 (18%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L Q V +EI++L LG G + V+ G+ R E
Sbjct 155 LQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAEEVA--------------------- 193
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+ KV + + DI + ++ H ++ GVC + P ++ EY HG L
Sbjct 194 ----IKKVREQNETDI--------KHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQL 241
Query 696 DVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
LR R P +++V + +AS ++YL ++H ++ N+L+ +
Sbjct 242 YEVLRAGRKITP---RLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTH-------TD 291
Query 754 FIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+K+SD G + ++ + WLAPE + +S +D W FG L E+
Sbjct 292 AVKISDFGTSKELSDKSTKMSFAGTVAWLAPEVIRN--EPVSEKVDIWSFGVVLWEL-LT 348
Query 811 GEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866
GE P + S LP PS CP L Q +P RPSFR L L
Sbjct 349 GEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHL 407
>sp|C0LGQ7|Y4245_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At4g20450 OS=Arabidopsis thaliana OX=3702
GN=At4g20450 PE=1 SV=1
Length=898
Score = 100 bits (249), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 72/203 (35%), Positives = 108/203 (53%), Gaps = 16/203 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LGEG FG V + ND E VAVK L ++ Q +K E+D+L ++H +++
Sbjct 595 RPLGEGGFGVV---YHGNVNDN--EQVAVKVL-SESSAQGYKQFKAEVDLLLRVHHINLV 648
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHA 1016
G C D+G+ L L+ EY+ G+L+ +L R + L A + +G+ YLH
Sbjct 649 TLVGYC-DEGQH-LVLIYEYMSNGNLKQHLSGENSRSPLSWENRLRIAAETAQGLEYLHI 706
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRD+ + N+LLDN+ K+GDFGL+++ P G E + SP + PE
Sbjct 707 GCKPPMIHRDIKSMNILLDNNFQAKLGDFGLSRSFPVGSETHVSTNVAGSPGY-LDPEYY 765
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
+ SDV+SFGV L E++T
Sbjct 766 RTNWLTEKSDVFSFGVVLLEIIT 788
Score = 52.4 bits (124), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 64/237 (27%), Positives = 97/237 (41%), Gaps = 35/237 (15%)
Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660
TN +E L G G G ++D + +V +KVL S F
Sbjct 590 TNNFERPLGEGGFGVVYHGNVNDNE------------QVAVKVLSESSAQGYKQFKAEVD 637
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQL 718
L+ +V H +L + G C G +++ EY+ +G L L E P++W ++ +A +
Sbjct 638 LLLRVHHINLVTLVGYCDEGQHLVLIYEYMSNGNLKQHLSGENSRSPLSWENRLRIAAET 697
Query 719 ASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGALSR-E 770
A L YL ++H ++ NILL A KL D G+ +G+ +
Sbjct 698 AQGLEYLHIGCKPPMIHRDIKSMNILLDNNFQA-------KLGDFGLSRSFPVGSETHVS 750
Query 771 ERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
V P +L PE N L+ D + FG LLEI Q+R EK H
Sbjct 751 TNVAGSPGYLDPEYYR--TNWLTEKSDVFSFGVVLLEIITSQPVIDQTR---EKSHI 802
>sp|Q9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 OS=Homo
sapiens OX=9606 GN=STK24 PE=1 SV=1
Length=443
Score = 98.2 bits (243), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 77/274 (28%), Positives = 125/274 (46%), Gaps = 36/274 (13%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
K+ +G+G FG+V + ++ T ++VA+K + + +QEI +L +
Sbjct 38 KLEKIGKGSFGEV----FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPY 93
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ KY G + L ++MEY+ GS D L + Q+ ++I +G+ YLH++
Sbjct 94 VTKYYGSY--LKDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEK 151
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ A NVLL VK+ DFG+A + + R FW APE +K+ +
Sbjct 152 KIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQ---IKRNTFVGTPFWMAPEVIKQSAY 208
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+D+WS G+T EL + PP L M VL L +P+ +
Sbjct 209 DSKADIWSLGITAIEL-----ARGEPPHSELH-------PMKVLFL---------IPKNN 247
Query 1139 KCPCE------VYHLMKNCWETEASFRPTFENLI 1166
E + ++ C E SFRPT + L+
Sbjct 248 PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELL 281
Score = 54.7 bits (130), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 74/330 (22%), Positives = 133/330 (40%), Gaps = 67/330 (20%)
Query 544 CFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603
+ RR LP PG ++NL +A P L T+L +G+G+ V
Sbjct 11 ALNKRRATLPHPGGSTNL------KADPEEL--------------FTKLEKIGKGSFGEV 50
Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLM 662
++G +D+ R Q++ V +K++D D + +++
Sbjct 51 FKG--------------IDN---------RTQKV-VAIKIIDLEEAEDEIEDIQQEITVL 86
Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWLRRERGHVPMAWKMVVAQQLASA 721
SQ ++ +G ++ + ++ EY+ G LD+ E G + + +++
Sbjct 87 SQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL---EPGPLDETQIATILREILKG 143
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS-----REERVERI 776
L YL ++ +H ++ N+LL+ G +KL+D GV G L+ R V
Sbjct 144 LDYLHSEKKIHRDIKAANVLLSEHG-------EVKLADFGVA-GQLTDTQIKRNTFVGTP 195
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH--RLP 834
W+APE + A + D W G T +E+ GE P P + + + L
Sbjct 196 FWMAPEVIKQSA--YDSKADIWSLGITAIELA-RGEPPHSELHPMKVLFLIPKNNPPTLE 252
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
L CL EP+ RP+ + +L+
Sbjct 253 GNYSKPLKEFVEACLNKEPSFRPTAKELLK 282
>sp|Q80YP0|CDK3_MOUSE Cyclin-dependent kinase 3 OS=Mus musculus
OX=10090 GN=Cdk3 PE=1 SV=3
Length=304
Score = 95.9 bits (237), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 69/205 (34%), Positives = 103/205 (50%), Gaps = 15/205 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955
+K+ +GEG +G V Y N TG++VA+K ++ D + S +EI +L+ L
Sbjct 4 FQKVEKIGEGTYGVV----YKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKELK 59
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013
H +IIK EK L +V E++ L D P + L + + Q+ EG+++
Sbjct 60 HPNIIKLLDVVHR--EKKLYMVFEFLTQDLKRHMDSSPTSELPLPVVKSYLAQLLEGVSF 117
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072
H+ IHRDL +N+LLD +K+ DFGLA+A Y + WY APE
Sbjct 118 CHSHRVIHRDLKPQNLLLDGLGAIKLADFGLARAFGVPLRTY----THEVVTLWYRAPEI 173
Query 1073 LKEYKFY-YASDVWSFGVTLYELLT 1096
L KFY A D+WS G E++T
Sbjct 174 LLGSKFYSTAVDIWSIGCIFAEMVT 198
Score = 42.0 bits (97), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 67/307 (22%), Positives = 116/307 (38%), Gaps = 65/307 (21%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-LDPSHH 649
++ +G+GT VY+ R +V G +L + K+ LD
Sbjct 6 KVEKIGEGTYGVVYKARNKVTG-----------------------QLVALKKIRLDLEAE 42
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
+ SL+ ++ H ++ + V R + MV E++ +P+
Sbjct 43 GVPSTAVREISLLKELKHPNIIKLLDVVHREKKLYMVFEFLTQDLKRHMDSSPTSELPLP 102
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLG 765
QL +S+ + ++H ++ +N+LL LG IKL+D G+ G+
Sbjct 103 VVKSYLAQLLEGVSFCHSHRVIHRDLKPQNLLLDGLGA-------IKLADFGLARAFGVP 155
Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEA------- 813
+ V + + APE L G+ STA+D W G E+ F G++
Sbjct 156 LRTYTHEVVTLWYRAPEILL-GSKFYSTAVDIWSIGCIFAEMVTGKALFPGDSEIDQLFR 214
Query 814 -------------PLQSRSPSEKEHFYQRQHRLPEPSCPQLA----TLTSQCLTYEPTQR 856
P S+ P + F + + E P L L + L Y+P+QR
Sbjct 215 IFRTLGTPSEATWPGVSQMPDYQSSFPKWSRKGLEEIVPSLGPEGKDLLLRLLQYDPSQR 274
Query 857 PSFRTIL 863
S +T L
Sbjct 275 ISAKTAL 281
>sp|Q99N57|RAF1_MOUSE RAF proto-oncogene serine/threonine-protein
kinase OS=Mus musculus OX=10090 GN=Raf1 PE=1 SV=2
Length=648
Score = 99.8 bits (247), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 68/199 (34%), Positives = 102/199 (51%), Gaps = 17/199 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+
Sbjct 355 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILL 407
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++
Sbjct 408 FMGY---MTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 464
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076
IHRD+ + N+ L VKIGDFGLA +V + S V W APE ++ +
Sbjct 465 IHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-VLWMAPEVIRMQDDN 523
Query 1077 KFYYASDVWSFGVTLYELL 1095
F + SDV+S+G+ LYEL+
Sbjct 524 PFSFQSDVYSYGIVLYELM 542
Score = 62.8 bits (151), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 70/286 (24%), Positives = 127/286 (44%), Gaps = 32/286 (11%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688
G+ G +LKV+DP+ + AF +++ + H ++ G + +N+ +VT+
Sbjct 366 GKWHGDVAVKILKVVDPTPEQLQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 422
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ E L L + M + +A+Q A + YL KN++H ++ NI L
Sbjct 423 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF-----LH 477
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFG 801
EG + +K+ D G+ G+ E+ + W+APE + N S D + +G
Sbjct 478 EGLT--VKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYG 535
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854
L E+ GE P + ++ F R + P+ S CP+ + L + C+
Sbjct 536 IVLYEL-MAGELPYAHINNRDQIIFMVGRGYASPDLSRLYKNCPKAMKRLVADCVKKVKE 594
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+RP F IL + LQ H+L + + AS+P++ + + I
Sbjct 595 ERPLFPQILSSIELLQ-HSLPKI-----NRSASEPSLHRAAHTEDI 634
>sp|Q84M95|PBL28_ARATH Probable serine/threonine-protein kinase
PBL28 OS=Arabidopsis thaliana OX=3702 GN=PBL28 PE=2 SV=1
Length=375
Score = 97.1 bits (240), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 83/228 (36%), Positives = 116/228 (51%), Gaps = 33/228 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL------KADCGPQHRSGWKQEIDILRTLYH 956
LG+G FG+V Y T TGE+VA+K + KAD + R E+DIL L H
Sbjct 82 LGKGGFGRV----YQGTLK-TGEVVAIKKMDLPTFKKADGEREFRV----EVDILSRLDH 132
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGM 1011
+++ G C D K LV EY+ G+L+D+L + I A++ L A +G+
Sbjct 133 PNLVSLIGYCADG--KHRFLVYEYMQNGNLQDHL--NGIKEAKISWPIRLRIALGAAKGL 188
Query 1012 AYLHAQH-----YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
AYLH+ +HRD + NVLLD++ KI DFGLAK +PEG + V
Sbjct 189 AYLHSSSSVGIPIVHRDFKSTNVLLDSNYNAKISDFGLAKLMPEGKDTC-VTARVLGTFG 247
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLT---HCDSSQSPPTKFLEL 1111
++ PE K SD+++FGV L ELLT D +Q P + L L
Sbjct 248 YFDPEYTSTGKLTLQSDIYAFGVVLLELLTGRRAVDLTQGPNEQNLVL 295
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 70/304 (23%), Positives = 120/304 (39%), Gaps = 64/304 (21%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LG+G VY+G L+ +G+ K D P D +E RV + +L
Sbjct 82 LGKGGFGRVYQGTLK---TGEVVAIKKMDL-PTFKKADGEREFRVEVDIL---------- 127
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
S++ H +L + G C G +V EY+++G L L + ++W ++
Sbjct 128 --------SRLDHPNLVSLIGYCADGKHRFLVYEYMQNGNLQDHLNGIK-EAKISWPIRL 178
Query 713 VVAQQLASALSYLENKN-----LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----- 762
+A A L+YL + + +VH + N+LL ++ K+SD G+
Sbjct 179 RIALGAAKGLAYLHSSSSVGIPIVHRDFKSTNVLL-------DSNYNAKISDFGLAKLMP 231
Query 763 -GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
G + + PE G +L + D + FG LLE+ A ++ P+
Sbjct 232 EGKDTCVTARVLGTFGYFDPEYTSTGKLTLQS--DIYAFGVVLLELLTGRRAVDLTQGPN 289
Query 822 EKEHFYQRQH--------------RLPEPS-----CPQLATLTSQCLTYEPTQRPSFRTI 862
E+ Q ++ LP S A L S+C+ E +RPS
Sbjct 290 EQNLVLQVRNILNDRKKLRKVIDVELPRNSYSMEAITMFADLASRCIRIESKERPSVMDC 349
Query 863 LRDL 866
+++L
Sbjct 350 VKEL 353
>sp|B0LT89|STK24_RAT Serine/threonine-protein kinase 24 OS=Rattus
norvegicus OX=10116 GN=Stk24 PE=2 SV=1
Length=431
Score = 97.8 bits (242), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 77/274 (28%), Positives = 125/274 (46%), Gaps = 36/274 (13%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
K+ +G+G FG+V + ++ T ++VA+K + + +QEI +L +
Sbjct 26 KLEKIGKGSFGEV----FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPY 81
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ KY G + L ++MEY+ GS D L + Q+ ++I +G+ YLH++
Sbjct 82 VTKYYGSY--LKDTKLWIIMEYLGGGSALDLLEPGPLDEIQIATILREILKGLDYLHSEK 139
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ A NVLL VK+ DFG+A + + R FW APE +K+ +
Sbjct 140 KIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQ---IKRNTFVGTPFWMAPEVIKQSAY 196
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+D+WS G+T EL + PP L M VL L +P+ +
Sbjct 197 DSKADIWSLGITAIEL-----AKGEPPHSELH-------PMKVLFL---------IPKNN 235
Query 1139 KCPCE------VYHLMKNCWETEASFRPTFENLI 1166
E + ++ C E SFRPT + L+
Sbjct 236 PPTLEGSYSRPLKEFVEACLNKEPSFRPTAKELL 269
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 68/305 (22%), Positives = 127/305 (42%), Gaps = 48/305 (16%)
Query 570 SPRTLNLSQLSFHRVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
SP L + + D +E+ T+L +G+G+ V++G +D+
Sbjct 4 SPVQSGLPGMQTLKADPEELFTKLEKIGKGSFGEVFKG--------------IDN----- 44
Query 629 PGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
R Q++ V +K++D D + +++SQ ++ +G ++ + ++
Sbjct 45 ----RTQKV-VAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIM 99
Query 688 EYVEHGP-LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
EY+ G LD+ E G + + +++ L YL ++ +H ++ N+LL+ G
Sbjct 100 EYLGGGSALDLL---EPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHG 156
Query 747 LAEGTSPFIKLSDPGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
+KL+D GV G L+ R V W+APE + A + D W G
Sbjct 157 -------EVKLADFGVA-GQLTDTQIKRNTFVGTPFWMAPEVIKQSA--YDSKADIWSLG 206
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSF 859
T +E+ GE P P + + + L L CL EP+ RP+
Sbjct 207 ITAIELA-KGEPPHSELHPMKVLFLIPKNNPPTLEGSYSRPLKEFVEACLNKEPSFRPTA 265
Query 860 RTILR 864
+ +L+
Sbjct 266 KELLK 270
>sp|Q3SWY6|STK25_BOVIN Serine/threonine-protein kinase 25 OS=Bos
taurus OX=9913 GN=STK25 PE=2 SV=1
Length=426
Score = 97.8 bits (242), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 77/274 (28%), Positives = 124/274 (45%), Gaps = 36/274 (13%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
K+ +G+G FG+V Y ++ T E+VA+K + + +QEI +L +
Sbjct 22 KLDRIGKGSFGEV----YKGIDNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPY 77
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I +Y G + L ++MEY+ GS D L + + ++I +G+ YLH++
Sbjct 78 ITRYFGSYLKSTK--LWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSER 135
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ A NVLL VK+ DFG+A + + R FW APE +K+ +
Sbjct 136 KIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQ---IKRNTFVGTPFWMAPEVIKQSAY 192
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+ +D+WS G+T EL + PP L M VL L +P+
Sbjct 193 DFKADIWSLGITAIEL-----AKGEPPNSDLH-------PMRVLFL---------IPKNS 231
Query 1139 KCPCEVYH------LMKNCWETEASFRPTFENLI 1166
E +H ++ C + FRPT + L+
Sbjct 232 PPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELL 265
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 66/298 (22%), Positives = 124/298 (42%), Gaps = 60/298 (20%)
Query 583 RVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
RVD +E+ T+L +G+G+ VY+G +D+ R +E+ V +
Sbjct 13 RVDPEELFTKLDRIGKGSFGEVYKG--------------IDN---------RTKEV-VAI 48
Query 642 KVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWL 699
K++D D + +++SQ ++ G ++ + ++ EY+ G LD+
Sbjct 49 KIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLL- 107
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ G + + + +++ L YL ++ +H ++ N+LL+ G +KL+D
Sbjct 108 --KPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQG-------DVKLAD 158
Query 760 PGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
GV G L+ R V W+APE + A D W G T +E+
Sbjct 159 FGVA-GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKA--DIWSLGITAIELA------ 209
Query 815 LQSRSPSEKEHFYQRQHRLPEPSCPQL--------ATLTSQCLTYEPTQRPSFRTILR 864
+ P+ H + +P+ S P L CL +P RP+ + +L+
Sbjct 210 -KGEPPNSDLHPMRVLFLIPKNSPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLK 266
>sp|Q99KH8|STK24_MOUSE Serine/threonine-protein kinase 24 OS=Mus
musculus OX=10090 GN=Stk24 PE=1 SV=1
Length=431
Score = 97.8 bits (242), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 77/274 (28%), Positives = 125/274 (46%), Gaps = 36/274 (13%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
K+ +G+G FG+V + ++ T ++VA+K + + +QEI +L +
Sbjct 26 KLEKIGKGSFGEV----FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPY 81
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ KY G + L ++MEY+ GS D L + Q+ ++I +G+ YLH++
Sbjct 82 VTKYYGSY--LKDTKLWIIMEYLGGGSALDLLEPGPLDEIQIATILREILKGLDYLHSEK 139
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ A NVLL VK+ DFG+A + + R FW APE +K+ +
Sbjct 140 KIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQ---IKRNTFVGTPFWMAPEVIKQSAY 196
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+D+WS G+T EL + PP L M VL L +P+ +
Sbjct 197 DSKADIWSLGITAIEL-----AKGEPPHSELH-------PMKVLFL---------IPKNN 235
Query 1139 KCPCE------VYHLMKNCWETEASFRPTFENLI 1166
E + ++ C E SFRPT + L+
Sbjct 236 PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELL 269
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 56/244 (23%), Positives = 102/244 (42%), Gaps = 23/244 (9%)
Query 630 GRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
G D + V +K++D D + +++SQ ++ +G ++ + ++ E
Sbjct 41 GIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIME 100
Query 689 YVEHGP-LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
Y+ G LD+ E G + + +++ L YL ++ +H ++ N+LL+ G
Sbjct 101 YLGGGSALDLL---EPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHG- 156
Query 748 AEGTSPFIKLSDPGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+KL+D GV G L+ R V W+APE + A + D W G
Sbjct 157 ------EVKLADFGVA-GQLTDTQIKRNTFVGTPFWMAPEVIKQSA--YDSKADIWSLGI 207
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
T +E+ GE P P + + + L L CL EP+ RP+ +
Sbjct 208 TAIELA-KGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAK 266
Query 861 TILR 864
+L+
Sbjct 267 ELLK 270
>sp|Q869X3|Y9851_DICDI Probable serine/threonine-protein kinase
DDB_G0275165 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0275165
PE=3 SV=1
Length=921
Score = 100 bits (248), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 83/278 (30%), Positives = 133/278 (48%), Gaps = 33/278 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWK---QEIDILRTLYHEH 958
+G G FGKV + G+ + +K + +D P K +EI L+ L H +
Sbjct 29 IGSGGFGKVYQGVLN------GKEIGIKKITISDNDPNRDILLKFLEREIYTLKMLSHPN 82
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--FAQQICEGMAYLHA 1016
+IK+ G E E+SL L+ E V G L Y+ SI + L A+ I MAYLH
Sbjct 83 VIKFYGIAE--KERSLFLLTELVSGGDLHWYIKNKSIDITWKLKVKIARDIAASMAYLHE 140
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRDL + N+L+ + ++K+ D GLA+ + + + D W APE L
Sbjct 141 NGVIHRDLKSTNLLVAENWVIKVCDMGLARKMDKSEKSKMTICGTDD---WMAPEVLIGE 197
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
++ + DV+SFG+ L EL+T + + P E +G+ Q L+++
Sbjct 198 EYDASCDVFSFGMVLIELITRENLT---PRIRNEDLGVDQK----FFLSKV--------- 241
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
P CP E+ L+ C + S RP+ N++ +L+ + E
Sbjct 242 PADCPKELLRLVSECCKVAPSGRPSASNILGLLEYILE 279
Score = 61.6 bits (148), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 69/286 (24%), Positives = 123/286 (43%), Gaps = 40/286 (14%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
D+ + LS +G G VY+G L G++ G + ++ +
Sbjct 19 DEIKFDPLSIIGSGGFGKVYQGVLN--------------------GKEIGIK-KITISDN 57
Query 645 DPSHHDIALAFYE-TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
DP + DI L F E + +SH ++ +G+ + ++TE V G L +++ +
Sbjct 58 DP-NRDILLKFLEREIYTLKMLSHPNVIKFYGIAEKERSLFLLTELVSGGDLHWYIKNKS 116
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ K+ +A+ +A++++YL ++H ++ N+L+A + IK+ D G+
Sbjct 117 IDITWKLKVKIARDIAASMAYLHENGVIHRDLKSTNLLVAENWV-------IKVCDMGLA 169
Query 764 LGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
E+ I W+APE L G + D + FG L+E+ L R
Sbjct 170 RKMDKSEKSKMTICGTDDWMAPEVLIG--EEYDASCDVFSFGMVLIELI--TRENLTPRI 225
Query 820 PSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTIL 863
+E Q+ P+ CP +L L S+C P+ RPS IL
Sbjct 226 RNEDLGVDQKFFLSKVPADCPKELLRLVSECCKVAPSGRPSASNIL 271
>sp|Q9XI87|VIK_ARATH Serine/threonine-protein kinase VIK OS=Arabidopsis
thaliana OX=3702 GN=VIK PE=1 SV=1
Length=438
Score = 97.8 bits (242), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 84/282 (30%), Positives = 133/282 (47%), Gaps = 34/282 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHII 960
+G+G FG++ + G VAVK + ++ E+D+L L H +I+
Sbjct 168 IGKGSFGEIVKAYW------RGTPVAVKRILPSLSDDRLVIQDFRHEVDLLVKLRHPNIV 221
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
++ G ++ K L L+ EY+ G L YL + + + FA I GM YLH +
Sbjct 222 QFLGAVTER--KPLMLITEYLRGGDLHQYLKEKGGLTPTTAVNFALDIARGMTYLHNEPN 279
Query 1018 HYIHRDLAARNVLLDNDRL--VKIGDFGLAK--AVPEGHEYYRVREDGDSPVFWY-APEC 1072
IHRDL RNVLL N +K+GDFGL+K V H+ Y++ G++ + Y APE
Sbjct 280 VIIHRDLKPRNVLLVNSSADHLKVGDFGLSKLIKVQNSHDVYKMT--GETGSYRYMAPEV 337
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
K ++ DV+SF + LYE+L PP E A+ R T
Sbjct 338 FKHRRYDKKVDVFSFAMILYEML-----EGEPPFANHEPYEAAKHVSDGHRPTF------ 386
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
R C ++ L+ CW+ + + RP+F +++ L+ + E
Sbjct 387 ---RSKGCTPDLRELIVKCWDADMNQRPSFLDILKRLEKIKE 425
Score = 60.1 bits (144), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 63/249 (25%), Positives = 109/249 (44%), Gaps = 27/249 (11%)
Query 639 VVLKVLDPSHHDIALA---FYETASLMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGP 694
V +K + PS D L F L+ ++ H ++ F+ V R P +++TEY+ G
Sbjct 186 VAVKRILPSLSDDRLVIQDFRHEVDLLVKLRHPNIVQFLGAVTERKPL-MLITEYLRGGD 244
Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENK--NLVHGNVCGRNILLARLGLAEGTS 752
L +L+ + G P + A +A ++YL N+ ++H ++ RN+LL ++
Sbjct 245 LHQYLKEKGGLTPTT-AVNFALDIARGMTYLHNEPNVIIHRDLKPRNVLLV-----NSSA 298
Query 753 PFIKLSDPGVG-LGALSREERVERIP-------WLAPECLPGGANSLSTAMDKWGFGATL 804
+K+ D G+ L + V ++ ++APE +D + F L
Sbjct 299 DHLKVGDFGLSKLIKVQNSHDVYKMTGETGSYRYMAPEVFK--HRRYDKKVDVFSFAMIL 356
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSC-PQLATLTSQCLTYEPTQRPSFRT 861
E+ +GE P + P E HR C P L L +C + QRPSF
Sbjct 357 YEM-LEGEPPFANHEPYEAAKHVSDGHRPTFRSKGCTPDLRELIVKCWDADMNQRPSFLD 415
Query 862 ILRDLTRLQ 870
IL+ L +++
Sbjct 416 ILKRLEKIK 424
>sp|F1NBT0|STK10_CHICK Serine/threonine-protein kinase 10 OS=Gallus
gallus OX=9031 GN=STK10 PE=3 SV=2
Length=969
Score = 100 bits (248), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 68/201 (34%), Positives = 106/201 (53%), Gaps = 19/201 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+LG+G FGKV Y N TG + A K ++ + EI+IL T H HI+K
Sbjct 41 ELGDGAFGKV----YKAKNKETGALAAAKVIETK-NEDELEDYMVEIEILATCDHPHIVK 95
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019
G +G+ L +++E+ P G++ + GL Q+ + +Q+ E + YLH++
Sbjct 96 LLGAFYWEGK--LWIMIEFCPGGAVDATMLELDRGLTEPQIQVICRQMLEALHYLHSKKI 153
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVFWYAP-----ECL 1073
IHRDL A NVLL D +K+ DFG+ AK V + + R+ +W AP E +
Sbjct 154 IHRDLKAGNVLLTQDGDIKLADFGVSAKNV----KTLQKRDSFIGTPYWMAPEVVMCETM 209
Query 1074 KEYKFYYASDVWSFGVTLYEL 1094
K+ + Y +D+WS G+TL E+
Sbjct 210 KDTPYDYKADIWSLGITLIEM 230
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 46/176 (26%), Positives = 77/176 (44%), Gaps = 18/176 (10%)
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV-RGPENIMVTEYVEHGPLD-VWL 699
KV++ + D + +++ H H+ + G G IM+ E+ G +D L
Sbjct 65 KVIETKNEDELEDYMVEIEILATCDHPHIVKLLGAFYWEGKLWIMI-EFCPGGAVDATML 123
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+RG + V+ +Q+ AL YL +K ++H ++ N+LL + G IKL+D
Sbjct 124 ELDRG-LTEPQIQVICRQMLEALHYLHSKKIIHRDLKAGNVLLTQDG-------DIKLAD 175
Query 760 PGV---GLGALSREERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808
GV + L + + P W+APE C D W G TL+E+
Sbjct 176 FGVSAKNVKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMA 231
>sp|G5ED65|VER1_CAEEL Protein ver-1 OS=Caenorhabditis elegans
OX=6239 GN=ver-1 PE=2 SV=1
Length=1083
Score = 100 bits (248), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 77/297 (26%), Positives = 125/297 (42%), Gaps = 55/297 (19%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
FHK L+ + +G GHFG V GT +VAVK+ + +E+ ++
Sbjct 798 FHKDSLEILEPIGSGHFGVVRRGILK----GTKTVVAVKSSSYRSSIGFQKVIVEELKLM 853
Query 952 RTL-YHEHIIKYKGC-CEDQGEKSLQLVMEYVPLGSLRDYLPR----------------- 992
+ H +++ G ++ L ++MEY+ G+LRD+L +
Sbjct 854 SAIPKHPNVLALVGAITKNLRHGELYILMEYIDGGNLRDFLQQRRNVFIDELHDNFDENI 913
Query 993 -------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+S+ L+ A QI GM +L +H +L R VL+ + ++I D+G+
Sbjct 914 PLIRPDFNSLSTTDLVGIAHQIANGMEWLGNVPCVHGNLCCRKVLISKTKTIRITDYGVG 973
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
R+ S + W APE ++ F SDVWSFG+ LYE+ T
Sbjct 974 D-----------RQRKSSSMRWMAPEAIEHQMFSSKSDVWSFGICLYEIFT--------- 1013
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
L G + + ++ G R +P+ CP +Y LM+ CW RP F
Sbjct 1014 -----LGGTPYPTCVTENILKHIKNGSRNLQPEYCPSALYDLMQLCWRAPPQDRPKF 1065
Score = 61.2 bits (147), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 47/163 (29%), Positives = 72/163 (44%), Gaps = 22/163 (13%)
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
+A Q+A+ + +L N VHGN+C R +L+++ + I+++D GVG R+ +
Sbjct 931 IAHQIANGMEWLGNVPCVHGNLCCRKVLISK-------TKTIRITDYGVG----DRQRKS 979
Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS-RSPSEKEHFYQRQHR 832
+ W+APE + S+ D W FG L EI G P + + + +H
Sbjct 980 SSMRWMAPEAIE--HQMFSSKSDVWSFGICLYEIFTLGGTPYPTCVTENILKHIKNGSRN 1037
Query 833 LPEPSCPQ-LATLTSQCLTYEPTQRPSFRTI-------LRDLT 867
L CP L L C P RP F L+DLT
Sbjct 1038 LQPEYCPSALYDLMQLCWRAPPQDRPKFSLCSELIEKQLKDLT 1080
>sp|Q9LDZ5|PBL21_ARATH Probable serine/threonine-protein kinase
PBL21 OS=Arabidopsis thaliana OX=3702 GN=PBL21 PE=1 SV=1
Length=381
Score = 97.1 bits (240), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 91/313 (29%), Positives = 143/313 (46%), Gaps = 43/313 (14%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R +++ LGEG FG+V Y D +G++VA+K L D G Q + E+ +L L
Sbjct 76 RNFREVNLLGEGGFGRV----YKGRLD-SGQVVAIKQLNPD-GLQGNREFIVEVLMLSLL 129
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICE 1009
+H +++ G C G++ L LV EY+P+GSL D+L + + + A
Sbjct 130 HHPNLVTLIGYCT-SGDQRL-LVYEYMPMGSLEDHLFDLESNQEPLSWNTRMKIAVGAAR 187
Query 1010 GMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G+ YLH I+RDL + N+LLD + K+ DFGLAK P G + V
Sbjct 188 GIEYLHCTANPPVIYRDLKSANILLDKEFSPKLSDFGLAKLGPVGDRTH-VSTRVMGTYG 246
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL---- 1122
+ APE K SD++ FGV L EL+T K ++L G QG+ ++
Sbjct 247 YCAPEYAMSGKLTVKSDIYCFGVVLLELITG--------RKAIDL-GQKQGEQNLVTWSR 297
Query 1123 -------RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV--- 1172
+ L++ R P +C ++ C EA +RP +++ L+ +
Sbjct 298 PYLKDQKKFGHLVDPSLRGKYPRRCLNYAIAIIAMCLNEEAHYRPFIGDIVVALEYLAAQ 357
Query 1173 ---HEKYQGQAPS 1182
HE +PS
Sbjct 358 SRSHEARNVSSPS 370
Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 71/267 (27%), Positives = 112/267 (42%), Gaps = 51/267 (19%)
Query 557 ETSNLIIMRGARASP------RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRV 610
E+ + I++ G SP R+ +L+ + +E+ + LG+G VY+GRL
Sbjct 43 ESISGILVNGKVNSPIPGGGARSFTFKELAAATRNFREV---NLLGEGGFGRVYKGRL-- 97
Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670
D GQ V +K L+P F ++S + H +L
Sbjct 98 ---------------------DSGQV--VAIKQLNPDGLQGNREFIVEVLMLSLLHHPNL 134
Query 671 AFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAW--KMVVAQQLASALSYLE- 726
+ G C G + ++V EY+ G L D E P++W +M +A A + YL
Sbjct 135 VTLIGYCTSGDQRLLVYEYMPMGSLEDHLFDLESNQEPLSWNTRMKIAVGAARGIEYLHC 194
Query 727 --NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERVE-RIPWLAPE 782
N +++ ++ NILL + SP KLSD G+ LG + V R+
Sbjct 195 TANPPVIYRDLKSANILLDK-----EFSP--KLSDFGLAKLGPVGDRTHVSTRVMGTYGY 247
Query 783 CLPGGANS--LSTAMDKWGFGATLLEI 807
C P A S L+ D + FG LLE+
Sbjct 248 CAPEYAMSGKLTVKSDIYCFGVVLLEL 274
>sp|Q9SF86|PCRK1_ARATH Serine/threonine-protein kinase PCRK1 OS=Arabidopsis
thaliana OX=3702 GN=PCRK1 PE=1 SV=1
Length=418
Score = 97.4 bits (241), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 71/204 (35%), Positives = 103/204 (50%), Gaps = 13/204 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG FG V D + ++ VAVK L G Q W E++ L + H +++K
Sbjct 90 IGEGGFGCVFRGTVRNLEDSSVKIEVAVKQL-GKRGLQGHKEWVTEVNFLGIVEHTNLVK 148
Query 962 YKGCCEDQGEKSLQ--LVMEYVPLGSLRDYLPRHSIGLAQL---LLFAQQICEGMAYLHA 1016
G C + E+ +Q LV EY+P S+ +L S+ + L AQ G+ YLH
Sbjct 149 LLGYCAEDDERGIQRLLVYEYMPNRSVEFHLSPRSLTVLTWDLRLRIAQDAARGLTYLHE 208
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPEC 1072
+ I RD + N+LLD D K+ DFGLA+ P EG + V D + + APE
Sbjct 209 EMEFQIIFRDFKSSNILLDEDWKAKLSDFGLARLGPSEGLTH--VSTDVVGTMGYAAPEY 266
Query 1073 LKEYKFYYASDVWSFGVTLYELLT 1096
++ + SDVW +GV LYEL+T
Sbjct 267 IQTGRLTSKSDVWGYGVFLYELIT 290
Score = 51.2 bits (121), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 55/239 (23%), Positives = 101/239 (42%), Gaps = 33/239 (14%)
Query 659 ASLMSQVSHTHLAFVHGVCV----RGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
+ + V HT+L + G C RG + ++V EY+ + ++ L R + W ++
Sbjct 135 VNFLGIVEHTNLVKLLGYCAEDDERGIQRLLVYEYMPNRSVEFHLS-PRSLTVLTWDLRL 193
Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+AQ A L+YL + ++ + NILL A+ + + P GL +S
Sbjct 194 RIAQDAARGLTYLHEEMEFQIIFRDFKSSNILLDEDWKAKLSDFGLARLGPSEGLTHVS- 252
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ- 828
+ V + + APE + G L++ D WG+G L E+ G P+ P ++ +
Sbjct 253 TDVVGTMGYAAPEYIQTG--RLTSKSDVWGYGVFLYEL-ITGRRPVDRNRPKGEQKLLEW 309
Query 829 --------RQHRL----------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
R+ +L P S +LA + ++CL RP +L + ++
Sbjct 310 VRPYLSDTRKFKLILDPRLEGKYPIKSVQKLAVVANRCLVRNSKARPKMSEVLEMVNKI 368
>sp|P09619|PGFRB_HUMAN Platelet-derived growth factor receptor
beta OS=Homo sapiens OX=9606 GN=PDGFRB PE=1 SV=1
Length=1106
Score = 100 bits (248), Expect = 7e-20, Method: Compositional matrix adjust.
Identities = 58/168 (35%), Positives = 87/168 (52%), Gaps = 14/168 (8%)
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ L+ F+ Q+ GM +L +++ +HRDLAARNVL+ +LVKI DFGLA+ + Y
Sbjct 798 LSYMDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNY 857
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ P+ W APE + + SDVWSFG+ L+E+ T T + EL
Sbjct 858 IS-KGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGG------TPYPELPMN 910
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
Q ++RG R+ +P E+Y +M+ CWE + RP F
Sbjct 911 EQ-------FYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPF 951
Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 42/155 (27%), Positives = 73/155 (47%), Gaps = 24/155 (15%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A+ + +L +KN VH ++ RN+L + EG +K+ D G+ + + +
Sbjct 809 QVANGMEFLASKNCVHRDLAARNVL-----ICEGK--LVKICDFGLARDIMRDSNYISKG 861
Query 776 -----IPWLAPECLPGGANSLSTAM-DKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-- 827
+ W+APE + NSL T + D W FG L EI G P +E+ FY
Sbjct 862 STFLPLKWMAPESI---FNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQ--FYNA 916
Query 828 -QRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSF 859
+R +R+ +P + ++ + +C + RP F
Sbjct 917 IKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPF 951
Score = 38.5 bits (88), Expect = 0.55, Method: Compositional matrix adjust.
Identities = 29/95 (31%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLY-HEH 958
R LG G FG+V + M VAVK LK+ + E+ I+ L H +
Sbjct 604 RTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLN 663
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993
++ G C G + ++ EY G L DYL R+
Sbjct 664 VVNLLGACTKGG--PIYIITEYCRYGDLVDYLHRN 696
>sp|Q55CA6|Y0146_DICDI Probable serine/threonine-protein kinase
DDB_G0270146 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0270146
PE=3 SV=1
Length=635
Score = 99.4 bits (246), Expect = 7e-20, Method: Compositional matrix adjust.
Identities = 75/267 (28%), Positives = 126/267 (47%), Gaps = 28/267 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G F V + N +G+ VA+K K+ + S E DIL+ L HE+I++
Sbjct 83 IGKGAFATV----FKGLNTLSGDFVAIKRFEKSKISNEQHSSVSTEFDILQRLNHENIVR 138
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLHAQHYI 1020
G ++ E + + +EY+ GSL L L+ + + + +G+ YLH + I
Sbjct 139 ILG--REENENYIYIFLEYMENGSLSTILNNFGTFPESLICNYVENVLKGLVYLHQEGVI 196
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLA-KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
HRD+ A N+L++ K+ DFG A + + E + Y V +P +W APE ++
Sbjct 197 HRDIKAANILINKAGEAKLSDFGTAGEIIKESDKRYSVV---GTP-YWMAPEVIEISGHC 252
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SD+WS G T+ EL T PP L +G + R+ + +R P PD
Sbjct 253 QVSDIWSLGCTIIELFTSY-----PPYFDLNPLG------AMYRICQ----DDRPPLPDD 297
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLI 1166
E+ + ++ C+ R T + L+
Sbjct 298 ISSELANFLERCFCKSTEERATAKELL 324
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 47/228 (21%), Positives = 92/228 (40%), Gaps = 21/228 (9%)
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
K+ + H ++ F ++ +++H ++ + G + EY+E+G L L
Sbjct 112 KISNEQHSSVSTEF----DILQRLNHENIVRILGREENENYIYIFLEYMENGSLSTILNN 167
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
G P + + + L YL + ++H ++ NIL+ + G A KLSD G
Sbjct 168 -FGTFPESLICNYVENVLKGLVYLHQEGVIHRDIKAANILINKAGEA-------KLSDFG 219
Query 762 VGLGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ ++ + W+APE + + D W G T++E+ F P
Sbjct 220 TAGEIIKESDKRYSVVGTPYWMAPEVIEISGH--CQVSDIWSLGCTIIEL-FTSYPPYFD 276
Query 818 RSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
+P + + R LP+ +LA +C +R + + +L
Sbjct 277 LNPLGAMYRICQDDRPPLPDDISSELANFLERCFCKSTEERATAKELL 324
>sp|Q7ZYJ0|TAO1B_XENLA Serine/threonine-protein kinase TAO1-B
OS=Xenopus laevis OX=8355 GN=taok1-b PE=2 SV=1
Length=1001
Score = 100 bits (248), Expect = 7e-20, Method: Compositional matrix adjust.
Identities = 80/239 (33%), Positives = 119/239 (50%), Gaps = 32/239 (13%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956
+R++G G FG V + +D T E+VA+K + + G Q W+ +E+ L+ + H
Sbjct 31 LREIGHGSFGAV-YFAHDAR---TSEVVAIKKM-SYSGKQSNEKWQDIIKEVKFLQRIQH 85
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014
+ I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL
Sbjct 86 PNSIEYKGCY--LREHTAWLVMEYC-LGSASDLLEVHKKPLQEIEIAAITHGALQGLAYL 142
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071
H+ + IHRD+ A N+LL VK+ DFG A V + + +P +W APE
Sbjct 143 HSHNLIHRDIKAGNILLTEPGQVKLADFGSASIVSPANSFV------GTP-YWMAPEVIL 195
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP----TKFLELIGIAQGQMTVLRLTE 1126
+ E ++ DVWS G+T EL + + PP L IAQ + L+ TE
Sbjct 196 AMDEGQYDGKVDVWSLGITCVEL-----AERKPPLFNMNAMSALYHIAQNESPTLQSTE 249
Score = 35.4 bits (80), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 26/88 (30%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781
L+YL + NL+H ++ NILL G +KL+D G V W+AP
Sbjct 139 LAYLHSHNLIHRDIKAGNILLTEPGQ-------VKLADFGSASIVSPANSFVGTPYWMAP 191
Query 782 EC-LPGGANSLSTAMDKWGFGATLLEIC 808
E L +D W G T +E+
Sbjct 192 EVILAMDEGQYDGKVDVWSLGITCVELA 219
>sp|Q55EC7|GEFX_DICDI RasGEF domain-containing serine/threonine-protein
kinase X OS=Dictyostelium discoideum OX=44689 GN=gefX
PE=2 SV=1
Length=960
Score = 99.8 bits (247), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 61/195 (31%), Positives = 101/195 (52%), Gaps = 11/195 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FG V CY G VA+K ++ P++ +E+ +L++L H I+ +
Sbjct 27 IGKGSFGSVFRGCY------LGLDVAIKKIEKADDPEYLKYIDREVSMLQSLRHPFIVNF 80
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G C L +V E+V G +R L + IG + + A + + M +LHA+ IH
Sbjct 81 SGICVHSS--GLYIVTEFVSGGDVRQLLKKTPPIGWDKRVSIAVDLAKAMVFLHAKKIIH 138
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RDL ++N+LLD + +++ DFG A+ + + + G W APE L + +
Sbjct 139 RDLKSKNILLDEFQRIRLCDFGFARMSEQTKKSRHMTMCGTEG--WVAPEILLGMSYDTS 196
Query 1082 SDVWSFGVTLYELLT 1096
DV+S+GV L EL+T
Sbjct 197 CDVFSYGVVLAELIT 211
Score = 71.2 bits (173), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 69/253 (27%), Positives = 110/253 (43%), Gaps = 38/253 (15%)
Query 637 LRVVLKVLDPSHHDIALAFYE-TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
L V +K ++ + L + + S++ + H + G+CV +VTE+V G +
Sbjct 43 LDVAIKKIEKADDPEYLKYIDREVSMLQSLRHPFIVNFSGICVHSSGLYIVTEFVSGGDV 102
Query 696 DVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L++ P+ W ++ +A LA A+ +L K ++H ++ +NILL
Sbjct 103 RQLLKKTP---PIGWDKRVSIAVDLAKAMVFLHAKKIIHRDLKSKNILLDEFQR------ 153
Query 754 FIKLSDPGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
I+L D G +S + + R W+APE L G S T+ D + +G L E
Sbjct 154 -IRLCD--FGFARMSEQTKKSRHMTMCGTEGWVAPEILLGM--SYDTSCDVFSYGVVLAE 208
Query 807 ICFDGEAP---LQSRSPS-----EKEHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQRP 857
+ G P L RSP E Q+ P CP +L ++ +C YEP RP
Sbjct 209 L-ITGRKPGVDLWVRSPETCFDINPEELKQKSI----PGCPSELISVCVECCLYEPLTRP 263
Query 858 SFRTILRDLTRLQ 870
F IL L Q
Sbjct 264 KFDEILSQLKVCQ 276
>sp|Q05030|PGFRB_RAT Platelet-derived growth factor receptor beta
OS=Rattus norvegicus OX=10116 GN=Pdgfrb PE=2 SV=2
Length=1097
Score = 99.8 bits (247), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 65/188 (35%), Positives = 94/188 (50%), Gaps = 19/188 (10%)
Query 980 YVPLGSLRDY---LPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034
YVP R Y L S + L+ F+ Q+ GM +L +++ +HRDLAARNVL+
Sbjct 777 YVPSAPERTYRATLINDSPVLSYTDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEG 836
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
+LVKI DFGLA+ + Y + P+ W APE + + SDVWSFG+ L+E+
Sbjct 837 KLVKICDFGLARDIMRDSNYIS-KGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEI 895
Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154
T T + EL Q ++RG R+ +P E+Y +M+ CWE
Sbjct 896 FTLGG------TPYPELPMNDQ-------FYNAIKRGYRMAQPAHASDEIYEIMQKCWEE 942
Query 1155 EASFRPTF 1162
+ RP F
Sbjct 943 KFETRPPF 950
Score = 49.3 bits (116), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 41/155 (26%), Positives = 73/155 (47%), Gaps = 24/155 (15%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A+ + +L +KN VH ++ RN+L + EG +K+ D G+ + + +
Sbjct 808 QVANGMEFLASKNCVHRDLAARNVL-----ICEGK--LVKICDFGLARDIMRDSNYISKG 860
Query 776 -----IPWLAPECLPGGANSLSTAM-DKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-- 827
+ W+APE + NSL T + D W FG L EI G P +++ FY
Sbjct 861 STFLPLKWMAPESI---FNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQ--FYNA 915
Query 828 -QRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSF 859
+R +R+ +P + ++ + +C + RP F
Sbjct 916 IKRGYRMAQPAHASDEIYEIMQKCWEEKFETRPPF 950
Score = 38.5 bits (88), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 29/95 (31%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLY-HEH 958
R LG G FG+V + M VAVK LK+ + E+ I+ L H +
Sbjct 603 RTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLN 662
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993
++ G C G + ++ EY G L DYL R+
Sbjct 663 VVNLLGACTKGG--PIYIITEYCRYGDLVDYLHRN 695
>sp|Q91821|MELK_XENLA Maternal embryonic leucine zipper kinase
OS=Xenopus laevis OX=8355 GN=melk PE=1 SV=2
Length=651
Score = 99.0 bits (245), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 70/204 (34%), Positives = 108/204 (53%), Gaps = 12/204 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+Y + +G G F KV L ++ TGE VA+K + + K EID ++ L
Sbjct 11 KYYELHETVGTGGFAKVKL----ASHLITGEKVAIKIMDKESLGDDLPRVKTEIDAMKNL 66
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAY 1013
H+H+ + E K + +V+EY P G L DY+ + + + +F +QI +AY
Sbjct 67 SHQHVCRLYHVIE--TPKKIFMVLEYCPGGELFDYIIAKDRLTEEEARVFFRQIVSAVAY 124
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+H+Q Y HRDL N+L+D D+ +K+ DFGL A P+G Y + SP + APE +
Sbjct 125 IHSQGYAHRDLKPENLLIDEDQNLKLIDFGLC-AKPKGGLDYHLMTCCGSPAY-AAPELI 182
Query 1074 KEYKFYYAS--DVWSFGVTLYELL 1095
+ K Y S D+WS GV +Y L+
Sbjct 183 QG-KAYIGSEADIWSMGVLMYALM 205
>sp|Q28GW8|MELK_XENTR Maternal embryonic leucine zipper kinase
OS=Xenopus tropicalis OX=8364 GN=melk PE=2 SV=1
Length=652
Score = 99.0 bits (245), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 70/204 (34%), Positives = 108/204 (53%), Gaps = 12/204 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+Y + +G G F KV L ++ TGE VA+K + + K EID ++ L
Sbjct 11 KYYELHETIGTGGFAKVKL----ASHLTTGEKVAIKIMDKESLGDDLPRVKTEIDAMKNL 66
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAY 1013
H+H+ + E + + +V+EY P G L DY+ + + + +F +QI +AY
Sbjct 67 SHQHVCRLYHVIETPNK--IFMVLEYCPGGELFDYIIAKDRLTEDEARVFFRQIVSAVAY 124
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+H+Q Y HRDL N+L+D D+ +K+ DFGL A P+G Y + SP + APE L
Sbjct 125 IHSQGYAHRDLKPENLLIDEDQNLKLIDFGLC-AKPKGGLDYHLMTCCGSPAY-AAPE-L 181
Query 1074 KEYKFYYAS--DVWSFGVTLYELL 1095
+ K Y S D+WS GV +Y L+
Sbjct 182 IQGKAYIGSEADIWSMGVLMYALM 205
Score = 35.0 bits (79), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 54/234 (23%), Positives = 96/234 (41%), Gaps = 19/234 (8%)
Query 638 RVVLKVLDPSHHDIALAFYETA-SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL- 695
+V +K++D L +T M +SH H+ ++ V + MV EY G L
Sbjct 38 KVAIKIMDKESLGDDLPRVKTEIDAMKNLSHQHVCRLYHVIETPNKIFMVLEYCPGGELF 97
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
D + ++R A V +Q+ SA++Y+ ++ H ++ N+L+ +
Sbjct 98 DYIIAKDRLTEDEA--RVFFRQIVSAVAYIHSQGYAHRDLKPENLLIDE-------DQNL 148
Query 756 KLSDPGVGL---GALSREERV--ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
KL D G+ G L + APE + G A + + D W G L+
Sbjct 149 KLIDFGLCAKPKGGLDYHLMTCCGSPAYAAPELIQGKA-YIGSEADIWSMGV-LMYALMC 206
Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
G P + + + ++ +P+ P L SQ L +P +R S + +L
Sbjct 207 GYLPFDDDNVMVLYKKIMRGKYEIPKWLSPGSVLLLSQMLQVDPKKRISVKHLL 260
>sp|P05622|PGFRB_MOUSE Platelet-derived growth factor receptor
beta OS=Mus musculus OX=10090 GN=Pdgfrb PE=1 SV=2
Length=1098
Score = 99.8 bits (247), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 65/188 (35%), Positives = 94/188 (50%), Gaps = 19/188 (10%)
Query 980 YVPLGSLRDY---LPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034
YVP R Y L S + L+ F+ Q+ GM +L +++ +HRDLAARNVL+
Sbjct 777 YVPSAPERTYRATLINDSPVLSYTDLVGFSYQVANGMDFLASKNCVHRDLAARNVLICEG 836
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
+LVKI DFGLA+ + Y + P+ W APE + + SDVWSFG+ L+E+
Sbjct 837 KLVKICDFGLARDIMRDSNYIS-KGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEI 895
Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154
T T + EL Q ++RG R+ +P E+Y +M+ CWE
Sbjct 896 FTLGG------TPYPELPMNDQ-------FYNAIKRGYRMAQPAHASDEIYEIMQKCWEE 942
Query 1155 EASFRPTF 1162
+ RP F
Sbjct 943 KFETRPPF 950
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 41/155 (26%), Positives = 73/155 (47%), Gaps = 24/155 (15%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775
Q+A+ + +L +KN VH ++ RN+L + EG +K+ D G+ + + +
Sbjct 808 QVANGMDFLASKNCVHRDLAARNVL-----ICEGK--LVKICDFGLARDIMRDSNYISKG 860
Query 776 -----IPWLAPECLPGGANSLSTAM-DKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-- 827
+ W+APE + NSL T + D W FG L EI G P +++ FY
Sbjct 861 STFLPLKWMAPESI---FNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQ--FYNA 915
Query 828 -QRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSF 859
+R +R+ +P + ++ + +C + RP F
Sbjct 916 IKRGYRMAQPAHASDEIYEIMQKCWEEKFETRPPF 950
Score = 38.1 bits (87), Expect = 0.58, Method: Compositional matrix adjust.
Identities = 29/95 (31%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLY-HEH 958
R LG G FG+V + M VAVK LK+ + E+ I+ L H +
Sbjct 603 RTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLN 662
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993
++ G C G + ++ EY G L DYL R+
Sbjct 663 VVNLLGACTKGG--PIYIITEYCRYGDLVDYLHRN 695
>sp|Q9SFT7|PBL26_ARATH Probable serine/threonine-protein kinase
PBL26 OS=Arabidopsis thaliana OX=3702 GN=PBL26 PE=2 SV=1
Length=414
Score = 97.1 bits (240), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 89/279 (32%), Positives = 134/279 (48%), Gaps = 22/279 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG+V Y + TG +VAVK L + G Q + E+ +L L+H+H++
Sbjct 85 IGEGGFGRV----YKGKLEKTGMIVAVKQLDRN-GLQGNKEFIVEVLMLSLLHHKHLVNL 139
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
G C D G++ L LV EY+ GSL D+L + + + A G+ YLH +
Sbjct 140 IGYCAD-GDQRL-LVYEYMSRGSLEDHLLDLTPDQIPLDWDTRIRIALGAAMGLEYLHDK 197
Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
I+RDL A N+LLD + K+ DFGLAK P G + + V + APE +
Sbjct 198 ANPPVIYRDLKAANILLDGEFNAKLSDFGLAKLGPVGDKQH-VSSRVMGTYGYCAPEYQR 256
Query 1075 EYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTV-LRLTELLER 1130
+ SDV+SFGV L EL+T D+++ P L+ AQ R EL +
Sbjct 257 TGQLTTKSDVYSFGVVLLELITGRRVIDTTR--PKDEQNLVTWAQPVFKEPSRFPELADP 314
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P+K + + C + EA+ RP +++ L
Sbjct 315 SLEGVFPEKALNQAVAVAAMCLQEEATVRPLMSDVVTAL 353
Score = 57.8 bits (138), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 75/311 (24%), Positives = 122/311 (39%), Gaps = 65/311 (21%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
K Q +G+G VY+G+L G + V +K LD
Sbjct 77 KNFRQECLIGEGGFGRVYKGKLEKTG------------------------MIVAVKQLDR 112
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGH 705
+ F ++S + H HL + G C G + ++V EY+ G L D L
Sbjct 113 NGLQGNKEFIVEVLMLSLLHHKHLVNLIGYCADGDQRLLVYEYMSRGSLEDHLLDLTPDQ 172
Query 706 VPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+P+ W ++ +A A L YL +K +++ ++ NILL A KLSD
Sbjct 173 IPLDWDTRIRIALGAAMGLEYLHDKANPPVIYRDLKAANILLDGEFNA-------KLSDF 225
Query 761 GVG-LGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ LG + ++ V + APE G L+T D + FG LLE+ G
Sbjct 226 GLAKLGPVGDKQHVSSRVMGTYGYCAPEYQRTG--QLTTKSDVYSFGVVLLEL-ITGRRV 282
Query 815 LQSRSPSEKEHF-------YQRQHRLPEPSCP------------QLATLTSQCLTYEPTQ 855
+ + P ++++ ++ R PE + P Q + + CL E T
Sbjct 283 IDTTRPKDEQNLVTWAQPVFKEPSRFPELADPSLEGVFPEKALNQAVAVAAMCLQEEATV 342
Query 856 RPSFRTILRDL 866
RP ++ L
Sbjct 343 RPLMSDVVTAL 353
>sp|O61122|SVKA_DICDI Serine/threonine-protein kinase svkA OS=Dictyostelium
discoideum OX=44689 GN=svkA PE=1 SV=1
Length=478
Score = 97.8 bits (242), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 103/211 (49%), Gaps = 13/211 (6%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
S DP + R K +G+G FG+V + N T E +A+K + +
Sbjct 3 SKKGDPEELYVRQEK----IGKGSFGEV----FKGINKKTNETIAIKTIDLEDAEDEIED 54
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLF 1003
+QEI++L + KY G +G K L ++MEY+ GS+ D + + +
Sbjct 55 IQQEINVLSQCESPFVTKYFGSFL-KGSK-LWIIMEYLAGGSVLDLMKPGPFDEGYIAII 112
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+++ +G+ YLH++ IHRD+ A NVLL VK+ DFG++ + + R
Sbjct 113 LRELLKGLEYLHSEGKIHRDIKAANVLLSASGDVKLADFGVSGQL---TDQMTKRNTFVG 169
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
FW APE +K+ + +D+WS G+T E+
Sbjct 170 TPFWMAPEVIKQTGYDSKADIWSMGITALEM 200
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 63/273 (23%), Positives = 111/273 (41%), Gaps = 42/273 (15%)
Query 614 GDPEEGKMDDED-------PLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQV 665
GDPEE + E + G ++ + +K +D D + +++SQ
Sbjct 6 GDPEELYVRQEKIGKGSFGEVFKGINKKTNETIAIKTIDLEDAEDEIEDIQQEINVLSQC 65
Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWLRRERGHVPMAWKMVVAQQLASALSY 724
+ G ++G + ++ EY+ G LD+ + G + ++ ++L L Y
Sbjct 66 ESPFVTKYFGSFLKGSKLWIIMEYLAGGSVLDLM---KPGPFDEGYIAIILRELLKGLEY 122
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS-----REERVERIPWL 779
L ++ +H ++ N+LL+ G +KL+D GV G L+ R V W+
Sbjct 123 LHSEGKIHRDIKAANVLLSASG-------DVKLADFGVS-GQLTDQMTKRNTFVGTPFWM 174
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP 839
APE + + D W G T LE+ GE P P + +P+ P
Sbjct 175 APEVI--KQTGYDSKADIWSMGITALEMA-KGEPPRADLHP------MRALFLIPKDPPP 225
Query 840 QLATLTSQ--------CLTYEPTQRPSFRTILR 864
L S+ CL +P QRP+ + +L+
Sbjct 226 TLEGNFSKGFKEFCALCLNKDPNQRPTAKDLLK 258
>sp|F4HQ17|LRL14_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE
PROTEIN KINASE-like 1.4 OS=Arabidopsis thaliana
OX=3702 GN=LRK10L-1.4 PE=2 SV=2
Length=663
Score = 99.0 bits (245), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 79/283 (28%), Positives = 135/283 (48%), Gaps = 18/283 (6%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R+LG+G FG V Y DG VAVK L + + +K EI+IL++L H +++
Sbjct 338 RELGDGGFGTVY---YGVLKDGRA--VAVKRL-YERSLKRVEQFKNEIEILKSLKHPNLV 391
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLH 1015
GC + + L LV EY+ G+L ++L + + L A + +++LH
Sbjct 392 ILYGCTS-RHSRELLLVYEYISNGTLAEHLHGNRAEARPLCWSTRLNIAIETASALSFLH 450
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ IHRD+ N+LLD++ VK+ DFGL++ P + G + PE +
Sbjct 451 IKGIIHRDIKTTNILLDDNYQVKVADFGLSRLFPMDQTHISTAPQGTPG--YVDPEYYQC 508
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF-LELIGIAQGQMTVLRLTELLERG--- 1131
Y+ SDV+SFGV L EL++ ++ + + L +A ++ L EL++
Sbjct 509 YQLNEKSDVYSFGVVLTELISSKEAVDITRHRHDINLANMAVSKIQNNALHELVDSSLGY 568
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ P + V L C + E RP + ++ IL+ + +
Sbjct 569 DNDPEVRRKMMAVAELAFRCLQQERDVRPAMDEIVEILRGIKD 611
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 46/171 (27%), Positives = 78/171 (46%), Gaps = 24/171 (14%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDVWLRRERGHV-PMAW-- 710
F ++ + H +L ++G R E ++V EY+ +G L L R P+ W
Sbjct 375 FKNEIEILKSLKHPNLVILYGCTSRHSRELLLVYEYISNGTLAEHLHGNRAEARPLCWST 434
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
++ +A + ASALS+L K ++H ++ NILL + +K++D G LSR
Sbjct 435 RLNIAIETASALSFLHIKGIIHRDIKTTNILL-------DDNYQVKVADFG-----LSRL 482
Query 771 ERVERIPW-LAPECLPGGAN-------SLSTAMDKWGFGATLLEICFDGEA 813
+++ AP+ PG + L+ D + FG L E+ EA
Sbjct 483 FPMDQTHISTAPQGTPGYVDPEYYQCYQLNEKSDVYSFGVVLTELISSKEA 533
>sp|Q9P289|STK26_HUMAN Serine/threonine-protein kinase 26 OS=Homo
sapiens OX=9606 GN=STK26 PE=1 SV=2
Length=416
Score = 97.1 bits (240), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 73/268 (27%), Positives = 121/268 (45%), Gaps = 24/268 (9%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
K+ +G+G FG+V + ++ T ++VA+K + + +QEI +L +
Sbjct 26 KLERIGKGSFGEV----FKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSY 81
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ KY G +G K L ++MEY+ GS D L Q+ ++I +G+ YLH++
Sbjct 82 VTKYYGSYL-KGSK-LWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEK 139
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ A NVLL VK+ DFG+A + + R FW APE +++ +
Sbjct 140 KIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIK---RNTFVGTPFWMAPEVIQQSAY 196
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+D+WS G+T EL + PP M +R+ L+ +
Sbjct 197 DSKADIWSLGITAIEL-----AKGEPPN----------SDMHPMRVLFLIPKNNPPTLVG 241
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ C + SFRPT + L+
Sbjct 242 DFTKSFKEFIDACLNKDPSFRPTAKELL 269
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 65/310 (21%), Positives = 129/310 (42%), Gaps = 58/310 (19%)
Query 570 SPRTLNLSQLSFHRVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
SP + + + + D +E+ T+L +G+G+ V++G +D+
Sbjct 4 SPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKG--------------IDN----- 44
Query 629 PGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
R Q++ V +K++D D + +++SQ +++ +G ++G + ++
Sbjct 45 ----RTQQV-VAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIM 99
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
EY+ G LR G + +++ L YL ++ +H ++ N+LL+ G
Sbjct 100 EYLGGGSALDLLRA--GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQG- 156
Query 748 AEGTSPFIKLSDPGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+KL+D GV G L+ R V W+APE + A + D W G
Sbjct 157 ------DVKLADFGVA-GQLTDTQIKRNTFVGTPFWMAPEVIQQSA--YDSKADIWSLGI 207
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLA--------TLTSQCLTYEPT 854
T +E+ + P+ H + +P+ + P L CL +P+
Sbjct 208 TAIELA-------KGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPS 260
Query 855 QRPSFRTILR 864
RP+ + +L+
Sbjct 261 FRPTAKELLK 270
>sp|Q9FPR3|EDR1_ARATH Serine/threonine-protein kinase EDR1 OS=Arabidopsis
thaliana OX=3702 GN=EDR1 PE=1 SV=1
Length=933
Score = 99.4 bits (246), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 81/275 (29%), Positives = 125/275 (45%), Gaps = 28/275 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G +G+V Y GT E+ K L D + ++ E+ I+R L H +++ +
Sbjct 675 IGLGSYGEV----YHADWHGT-EVAVKKFLDQDFSGAALAEFRSEVRIMRRLRHPNVVFF 729
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH-- 1018
G +L +V E++P GSL L P+ I + + A + GM LH
Sbjct 730 LGAV--TRPPNLSIVTEFLPRGSLYRILHRPKSHIDERRRIKMALDVAMGMNCLHTSTPT 787
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRDL N+L+DN+ VK+GDFGL++ H + + W APE L+
Sbjct 788 IVHRDLKTPNLLVDNNWNVKVGDFGLSRL---KHNTFLSSKSTAGTPEWMAPEVLRNEPS 844
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
DV+SFGV L+EL T L L M V+ R RL P
Sbjct 845 NEKCDVYSFGVILWELAT------------LRLPWRGMNPMQVVGAVGFQNR--RLEIPK 890
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ V ++ CW+T+ + RP+F L +LK ++
Sbjct 891 ELDPVVGRIILECWQTDPNLRPSFAQLTEVLKPLN 925
Score = 55.5 bits (132), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 61/246 (25%), Positives = 103/246 (42%), Gaps = 27/246 (11%)
Query 639 VVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V K LD ALA F +M ++ H ++ F G R P +VTE++ G L
Sbjct 694 AVKKFLDQDFSGAALAEFRSEVRIMRRLRHPNVVFFLGAVTRPPNLSIVTEFLPRGSLYR 753
Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENK--NLVHGNVCGRNILLARLGLAEGTSPFI 755
L R + H+ ++ +A +A ++ L +VH ++ N+L+ + +
Sbjct 754 ILHRPKSHIDERRRIKMALDVAMGMNCLHTSTPTIVHRDLKTPNLLV-------DNNWNV 806
Query 756 KLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--- 808
K+ D G+ LS + W+APE L + + D + FG L E+
Sbjct 807 KVGDFGLSRLKHNTFLSSKSTAGTPEWMAPEVLRNEPS--NEKCDVYSFGVILWELATLR 864
Query 809 --FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF---RTIL 863
+ G P+Q F R+ +P+ P + + +C +P RPSF +L
Sbjct 865 LPWRGMNPMQVVGAV---GFQNRRLEIPKELDPVVGRIILECWQTDPNLRPSFAQLTEVL 921
Query 864 RDLTRL 869
+ L RL
Sbjct 922 KPLNRL 927
>sp|Q924U5|TESK2_RAT Dual specificity testis-specific protein
kinase 2 OS=Rattus norvegicus OX=10116 GN=Tesk2 PE=2 SV=1
Length=570
Score = 98.2 bits (243), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 74/281 (26%), Positives = 125/281 (44%), Gaps = 33/281 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G F +V + + +G+ V ALK + +R+ +E+ ++ L H +I+++
Sbjct 64 IGSGFFSEV----FKVRHRASGQ---VMALKMNTLSSNRANLLKEMQLMNRLSHPNILRF 116
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G C QG+ L + EY+ G+L L + + + A I G++YLH + H
Sbjct 117 MGVCVHQGQ--LHALTEYINSGNLEQLLDSNLYLPWTVRVKLAYDIAVGLSYLHFKGIFH 174
Query 1022 RDLAARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
RDL ++N L+ D + DFGLA+ +P+ SP FW APE L++ +
Sbjct 175 RDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGSEKLAVVGSP-FWMAPEVLRDEPY 233
Query 1079 YYASDVWSFGVTLYELLT--HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+DV+S+G+ L E++ D P T+ L A M
Sbjct 234 NEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMV---------------- 277
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
CP + L NC + RP+FE + L+ + + Q
Sbjct 278 -GDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLEEIMSRLQ 317
Score = 62.4 bits (150), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 68/262 (26%), Positives = 111/262 (42%), Gaps = 36/262 (14%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
R GQ + + + L + ++ + LM+++SH ++ GVCV + +TEY+
Sbjct 78 RASGQVMALKMNTLSSNRANL----LKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYI 133
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR------ 744
G L+ L ++P ++ +A +A LSYL K + H ++ +N L+ R
Sbjct 134 NSGNLEQLLDSNL-YLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYS 192
Query 745 -----LGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
GLAE K+ D +G L+ V W+APE L + D +
Sbjct 193 AVVADFGLAE------KIPDASIGSEKLA---VVGSPFWMAPEVL--RDEPYNEKADVFS 241
Query 800 FGATLLEIC--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQR 856
+G L EI + R+ + + QH + + CP LT C +P R
Sbjct 242 YGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGD--CPSDFLQLTFNCCNMDPKLR 299
Query 857 PSFRTILRDL----TRLQPHNL 874
PSF I + L +RLQ L
Sbjct 300 PSFEEIGKTLEEIMSRLQEEEL 321
>sp|Q55E58|PATS1_DICDI Probable serine/threonine-protein kinase
pats1 OS=Dictyostelium discoideum OX=44689 GN=pats1 PE=3 SV=1
Length=3184
Score = 100 bits (248), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 85/264 (32%), Positives = 131/264 (50%), Gaps = 46/264 (17%)
Query 924 GEMVAVKALKA-----------DCG-PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
G+ VAVK LK D + + +++E ++ L H +I++ KG C D
Sbjct 2268 GQTVAVKKLKTIENLDSPIEINDISLSKAFNEFRRECWVMSELEHPNIVQLKGLCLD--- 2324
Query 972 KSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQH--YIHRDLAAR 1027
L +V EY+P G+L +L + + + L L A I GMA+LH+ IHRDL +
Sbjct 2325 -PLCIVTEYLPHGNLYSFLHKPEMEFSWLFRLKVALDISSGMAFLHSSTPPIIHRDLKSP 2383
Query 1028 NVLL-----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK-FYYA 1081
N+LL + + K+ DFGL+ G ++ ++P+ W APE L + K
Sbjct 2384 NILLASINENAQTIAKVVDFGLS-----GLQHTITNRGVENPL-WLAPEILNKTKEASTQ 2437
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
+DV++FGV L+EL+T D F E+ G MT++ E + GER P+ CP
Sbjct 2438 TDVYAFGVILWELVTRKD-------YFGEI-----GFMTLIE--EKVINGERPKIPEDCP 2483
Query 1142 CEVYHLMKNCWETEASFRPTFENL 1165
L+ CW+T+AS RP F +
Sbjct 2484 EMYSKLIVECWQTDASQRPKFSEI 2507
Score = 69.7 bits (169), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 66/242 (27%), Positives = 114/242 (47%), Gaps = 21/242 (9%)
Query 649 HDIALA-----FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+DI+L+ F +MS++ H ++ + G+C+ P I VTEY+ HG L +L +
Sbjct 2289 NDISLSKAFNEFRRECWVMSELEHPNIVQLKGLCL-DPLCI-VTEYLPHGNLYSFLHKPE 2346
Query 704 GHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
+++ VA ++S +++L + ++H ++ NILLA + E K+ D G
Sbjct 2347 MEFSWLFRLKVALDISSGMAFLHSSTPPIIHRDLKSPNILLASIN--ENAQTIAKVVDFG 2404
Query 762 V-GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC----FDGEAPLQ 816
+ GL VE WLAPE L ST D + FG L E+ + GE
Sbjct 2405 LSGLQHTITNRGVENPLWLAPEIL-NKTKEASTQTDVYAFGVILWELVTRKDYFGEIGFM 2463
Query 817 SRSPSEKEHFYQRQHRLPEPSCPQL-ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ E++ + ++PE CP++ + L +C + +QRP F I L ++
Sbjct 2464 TL--IEEKVINGERPKIPE-DCPEMYSKLIVECWQTDASQRPKFSEIEDRLIKIAEAMFP 2520
Query 876 DV 877
D+
Sbjct 2521 DI 2522
>sp|Q99JT2|STK26_MOUSE Serine/threonine-protein kinase 26 OS=Mus
musculus OX=10090 GN=Stk26 PE=1 SV=1
Length=416
Score = 96.7 bits (239), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 73/268 (27%), Positives = 121/268 (45%), Gaps = 24/268 (9%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
K+ +G+G FG+V + ++ T ++VA+K + + +QEI +L +
Sbjct 26 KLERIGKGSFGEV----FKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSY 81
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ KY G +G K L ++MEY+ GS D L Q+ ++I +G+ YLH++
Sbjct 82 VTKYYGSYL-KGSK-LWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEK 139
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ A NVLL VK+ DFG+A + + R FW APE +++ +
Sbjct 140 KIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQ---IKRNTFVGTPFWMAPEVIQQSAY 196
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+D+WS G+T EL + PP M +R+ L+ +
Sbjct 197 DSKADIWSLGITAIEL-----AKGEPPN----------SDMHPMRVLFLIPKNNPPTLIG 241
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ C + SFRPT + L+
Sbjct 242 DFTKSFKEFIDACLNKDPSFRPTAKELL 269
Score = 49.3 bits (116), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 65/310 (21%), Positives = 129/310 (42%), Gaps = 58/310 (19%)
Query 570 SPRTLNLSQLSFHRVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
SP + + + + D +E+ T+L +G+G+ V++G +D+
Sbjct 4 SPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKG--------------IDN----- 44
Query 629 PGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
R Q++ V +K++D D + +++SQ +++ +G ++G + ++
Sbjct 45 ----RTQQV-VAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIM 99
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
EY+ G LR G + +++ L YL ++ +H ++ N+LL+ G
Sbjct 100 EYLGGGSALDLLRA--GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQG- 156
Query 748 AEGTSPFIKLSDPGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+KL+D GV G L+ R V W+APE + A + D W G
Sbjct 157 ------DVKLADFGVA-GQLTDTQIKRNTFVGTPFWMAPEVIQQSA--YDSKADIWSLGI 207
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--------ATLTSQCLTYEPT 854
T +E+ + P+ H + +P+ + P L CL +P+
Sbjct 208 TAIELA-------KGEPPNSDMHPMRVLFLIPKNNPPTLIGDFTKSFKEFIDACLNKDPS 260
Query 855 QRPSFRTILR 864
RP+ + +L+
Sbjct 261 FRPTAKELLK 270
>sp|Q7T6X2|YR826_MIMIV Putative serine/threonine-protein kinase/receptor
R826 OS=Acanthamoeba polyphaga mimivirus OX=212035
GN=MIMI_R826 PE=3 SV=2
Length=1657
Score = 99.8 bits (247), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 75/248 (30%), Positives = 122/248 (49%), Gaps = 27/248 (11%)
Query 927 VAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
VA+K +K H G ++EI L+ L+H +II G + ++ +V EY+ G+
Sbjct 1423 VAIKKFIKQKIDENHLLGIREEIAFLKKLHHPNIITMVGAS--LKKPNICIVTEYMAKGN 1480
Query 986 LRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGD 1041
LRD + + L Q + I +G++YLH+ IHRD+ N+L+D + VKI D
Sbjct 1481 LRDAMRTCTPKLEWHQKIKILVNIAKGISYLHSFDPPIIHRDIKPSNILIDENWNVKIAD 1540
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FG A+ E R +P W APE ++ + DV+SFG+ ++E+LT
Sbjct 1541 FGFARIKEENAIMTRC----GTPC-WTAPEIIRNDIYDEKVDVFSFGIVMWEVLT----C 1591
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ P IG +++T + R P CP E LM+ CW +++ RPT
Sbjct 1592 KEP------FIG-----ANFMKITMDILEDVRPKIPQDCPEEFAKLMRKCWHAKSTKRPT 1640
Query 1162 FENLIPIL 1169
+++I +L
Sbjct 1641 MDDVIIVL 1648
Score = 95.1 bits (235), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 89/295 (30%), Positives = 135/295 (46%), Gaps = 45/295 (15%)
Query 891 VFHKRYLKKIRD--------------LGEGHFGKVSLYCYDPTNDGT--GEMVAVKALKA 934
+F R+ K I D LG G FG+V + GT G VAVK +
Sbjct 766 IFSLRFRKGISDDWEIDFHELELGEQLGTGAFGEV--------HKGTWRGTEVAVKMISP 817
Query 935 D--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992
D +K E+ ++ TL H +++ + + + +VME++ LGSL D L
Sbjct 818 DKTITKDIERNFKDEVRVMTTLRHPNVVLFMAASTKPPK--MCIVMEFMALGSLHDLLKN 875
Query 993 H---SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
I A + A Q +GM +LH+ HRDL + N+LLD VK+ DFGL K
Sbjct 876 ELIPDIPFALKVKIAYQASKGMHFLHSSGITHRDLKSLNLLLDIKWNVKVSDFGLTKFKS 935
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYK--FYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ + G + W APE L E + Y SDV+SFG+ ++EL+T + P
Sbjct 936 DVKSINPEKFAG--TIQWTAPEILSEDREVDYILSDVYSFGIIMWELIT-----RDQPYF 988
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
+ IA ++V+R ++L R + P E L+ +CW + + RPTF
Sbjct 989 GMSPAAIA---VSVIRDNYRPVISDQL-RSEVAP-EYIELLTSCWHFDPTIRPTF 1038
Score = 64.7 bits (156), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 61/256 (24%), Positives = 108/256 (42%), Gaps = 26/256 (10%)
Query 630 GRDRGQELRVVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
G RG E V +K++ P DI F + +M+ + H ++ + P+ +V
Sbjct 803 GTWRGTE--VAVKMISPDKTITKDIERNFKDEVRVMTTLRHPNVVLFMAASTKPPKMCIV 860
Query 687 TEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
E++ G L L+ E +P A K+ +A Q + + +L + + H ++ N+LL
Sbjct 861 MEFMALGSLHDLLKNELIPDIPFALKVKIAYQASKGMHFLHSSGITHRDLKSLNLLL--- 917
Query 746 GLAEGTSPFIKLSDPGV-----GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800
+K+SD G+ + +++ E+ I W APE L D + F
Sbjct 918 ----DIKWNVKVSDFGLTKFKSDVKSINPEKFAGTIQWTAPEILSEDREVDYILSDVYSF 973
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------CPQLATLTSQCLTYEP 853
G + E+ + P SP+ R + P S P+ L + C ++P
Sbjct 974 GIIMWEL-ITRDQPYFGMSPAAIAVSVIRDNYRPVISDQLRSEVAPEYIELLTSCWHFDP 1032
Query 854 TQRPSFRTILRDLTRL 869
T RP+F I+ L+ L
Sbjct 1033 TIRPTFLEIMTRLSNL 1048
Score = 44.3 bits (103), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 51/248 (21%), Positives = 103/248 (42%), Gaps = 35/248 (14%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+ + + +D +H L E + + ++ H ++ + G ++ P +VTEY+ G L
Sbjct 1427 KFIKQKIDENH---LLGIREEIAFLKKLHHPNIITMVGASLKKPNICIVTEYMAKGNLRD 1483
Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFI 755
+R + K+ + +A +SYL + + ++H ++ NIL+ + +
Sbjct 1484 AMRTCTPKLEWHQKIKILVNIAKGISYLHSFDPPIIHRDIKPSNILIDE-------NWNV 1536
Query 756 KLSDPGVGLGALSREERVER---IP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
K++D G + E + P W APE + + +D + FG + E+
Sbjct 1537 KIAD--FGFARIKEENAIMTRCGTPCWTAPEIIRN--DIYDEKVDVFSFGIVMWEV---- 1588
Query 812 EAPLQSRSPSEKEHFYQRQHRLPE---PSCPQ-----LATLTSQCLTYEPTQRPSFRTIL 863
L + P +F + + E P PQ A L +C + T+RP+ ++
Sbjct 1589 ---LTCKEPFIGANFMKITMDILEDVRPKIPQDCPEEFAKLMRKCWHAKSTKRPTMDDVI 1645
Query 864 RDLTRLQP 871
L + P
Sbjct 1646 IVLAKFCP 1653
>sp|O00506|STK25_HUMAN Serine/threonine-protein kinase 25 OS=Homo
sapiens OX=9606 GN=STK25 PE=1 SV=1
Length=426
Score = 97.1 bits (240), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 61/196 (31%), Positives = 99/196 (51%), Gaps = 9/196 (5%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
K+ +G+G FG+V Y ++ T E+VA+K + + +QEI +L +
Sbjct 22 KLDRIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPY 77
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I +Y G + L ++MEY+ GS D L + + ++I +G+ YLH++
Sbjct 78 ITRYFGSYLKSTK--LWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSER 135
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ A NVLL VK+ DFG+A + + R FW APE +K+ +
Sbjct 136 KIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQ---IKRNTFVGTPFWMAPEVIKQSAY 192
Query 1079 YYASDVWSFGVTLYEL 1094
+ +D+WS G+T EL
Sbjct 193 DFKADIWSLGITAIEL 208
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 66/298 (22%), Positives = 123/298 (41%), Gaps = 60/298 (20%)
Query 583 RVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
RVD +E+ T+L +G+G+ VY+G +D+ V V +
Sbjct 13 RVDPEELFTKLDRIGKGSFGEVYKG--------------IDNHTKEV----------VAI 48
Query 642 KVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWL 699
K++D D + +++SQ ++ G ++ + ++ EY+ G LD+
Sbjct 49 KIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLL- 107
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ G + + + +++ L YL ++ +H ++ N+LL+ G +KL+D
Sbjct 108 --KPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQG-------DVKLAD 158
Query 760 PGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
GV G L+ R V W+APE + A D W G T +E+
Sbjct 159 FGVA-GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKA--DIWSLGITAIELA------ 209
Query 815 LQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ--------CLTYEPTQRPSFRTILR 864
+ P+ H + +P+ S P L S+ CL +P RP+ + +L+
Sbjct 210 -KGEPPNSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLK 266
>sp|Q9ZUF4|RIPK_ARATH Serine/threonine-protein kinase RIPK OS=Arabidopsis
thaliana OX=3702 GN=RIPK PE=1 SV=1
Length=462
Score = 97.1 bits (240), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 88/253 (35%), Positives = 123/253 (49%), Gaps = 24/253 (9%)
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD-------LGEGHFGKV- 911
R + D++ + L++ L+++ SD VF LK I LGEG FG V
Sbjct 45 RLSILDMSNPSSNTLSEDLSIS--LAGSDLHVFTLAELKVITQSFSSTNFLGEGGFGPVH 102
Query 912 SLYCYDPTNDG-TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG-CCEDQ 969
+ D G + VAVK L + HR W E+ L L H++++K G CCE
Sbjct 103 KGFIDDKLRPGLKAQPVAVKLLDLEGLQGHRE-WLTEVMFLGQLKHKNLVKLIGYCCE-- 159
Query 970 GEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQH--YIHRDL 1024
E+ LV E++P GSL + L R S+ + + A G+ +LH I+RD
Sbjct 160 -EEHRTLVYEFMPRGSLENQLFRRYSASLPWSTRMKIAHGAATGLQFLHEAENPVIYRDF 218
Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHE-YYRVREDGDSPVFWYAPECLKEYKFYYASD 1083
A N+LLD+D K+ DFGLAK PEG + + R G + APE + SD
Sbjct 219 KASNILLDSDYTAKLSDFGLAKDGPEGDDTHVSTRVMGTQG--YAAPEYIMTGHLTARSD 276
Query 1084 VWSFGVTLYELLT 1096
V+SFGV L ELLT
Sbjct 277 VYSFGVVLLELLT 289
Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 72/289 (25%), Positives = 121/289 (42%), Gaps = 41/289 (14%)
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
G G +G +DD+ L PG + V +K+LD + + Q+ H +L
Sbjct 97 GFGPVHKGFIDDK--LRPGL---KAQPVAVKLLDLEGLQGHREWLTEVMFLGQLKHKNLV 151
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWL-RRERGHVPMAWKMVVAQQLASALSYL-ENKN 729
+ G C +V E++ G L+ L RR +P + +M +A A+ L +L E +N
Sbjct 152 KLIGYCCEEEHRTLVYEFMPRGSLENQLFRRYSASLPWSTRMKIAHGAATGLQFLHEAEN 211
Query 730 -LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIP-WLAPE 782
+++ + NILL A KLSD G+ ++ RV + APE
Sbjct 212 PVIYRDFKASNILLDSDYTA-------KLSDFGLAKDGPEGDDTHVSTRVMGTQGYAAPE 264
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE---------HFYQRQHRL 833
+ G L+ D + FG LLE+ + + RS E+ + ++ R+
Sbjct 265 YIMTG--HLTARSDVYSFGVVLLELLTGRRSVDKKRSSREQNLVDWARPMLNDPRKLSRI 322
Query 834 PEP---------SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
+P + ATL QCL++ P RP ++ L L+ +N
Sbjct 323 MDPRLEGQYSETGARKAATLAYQCLSHRPKNRPCMSAVVSILNDLKDYN 371
>sp|P09560|RAF1_XENLA RAF proto-oncogene serine/threonine-protein
kinase OS=Xenopus laevis OX=8355 GN=raf1 PE=2 SV=1
Length=638
Score = 98.2 bits (243), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 68/200 (34%), Positives = 101/200 (51%), Gaps = 17/200 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+
Sbjct 346 IGSGSFGTV----YKGKWHGD---VAVKILKVTDPTPEQLQAFRNEVAVLRKTRHVNILL 398
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++
Sbjct 399 FMGY---MTKDNLAIVTQWCEGSSLYYHLHVLDTKFQMFQLIDIARQTAQGMDYLHAKNI 455
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076
IHRD+ + N+ L VKIGDFGLA +V E + W APE ++
Sbjct 456 IHRDMKSNNIFLHEGLTVKIGDFGLATVKTRWSGSQQV-EQLTGSILWMAPEVIRMQDNN 514
Query 1077 KFYYASDVWSFGVTLYELLT 1096
F + SDV+S+G+ LYEL+T
Sbjct 515 PFSFQSDVYSYGIVLYELMT 534
Score = 57.0 bits (136), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 79/337 (23%), Positives = 133/337 (39%), Gaps = 59/337 (18%)
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615
G+ N I RG R S + + E+ S +G G+ VY+G+
Sbjct 315 GQEKNKIRARGQRDSSY--------YWEIIASEVMLSSRIGSGSFGTVYKGKWH------ 360
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675
G +LKV DP+ + AF +++ + H ++ G
Sbjct 361 ------------------GDVAVKILKVTDPTPEQLQ-AFRNEVAVLRKTRHVNILLFMG 401
Query 676 VCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGN 734
+ +N+ +VT++ E L L M + +A+Q A + YL KN++H +
Sbjct 402 YMTK--DNLAIVTQWCEGSSLYYHLHVLDTKFQMFQLIDIARQTAQGMDYLHAKNIIHRD 459
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGA 788
+ NI L EG + +K+ D G+ G+ E+ I W+APE +
Sbjct 460 MKSNNIF-----LHEGLT--VKIGDFGLATVKTRWSGSQQVEQLTGSILWMAPEVIRMQD 512
Query 789 NS-LSTAMDKWGFGATLLEICFDGEAPLQS-RSPSEKEHFYQRQHRLPEPS-----CPQ- 840
N+ S D + +G L E+ GE P R + R +P+ S CP+
Sbjct 513 NNPFSFQSDVYSYGIVLYEL-MTGELPYSHIRDRDQIIFLVGRGGVVPDLSKLYKNCPKA 571
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
+ L + + +RP F IL + LQ H+L +
Sbjct 572 MKRLVADSIKKLRDERPLFPQILSSIELLQ-HSLPKI 607
>sp|P18160|SPLA_DICDI Dual specificity protein kinase splA OS=Dictyostelium
discoideum OX=44689 GN=splA PE=1 SV=3
Length=2410
Score = 99.4 bits (246), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 88/297 (30%), Positives = 135/297 (45%), Gaps = 46/297 (15%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTLYHEH 958
+ +G+G FG+V + T+ VA+K + D S ++ E+ IL L H +
Sbjct 2119 QTIGKGFFGEVKRGYWRETD------VAIKIIYRDQFKTKSSLVMFQNEVGILSKLRHPN 2172
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ----LLLFAQQICEGMAYL 1014
++++ G C GE +V E++ GSLR +L H L Q L A I +GM YL
Sbjct 2173 VVQFLGACTAGGEDHHCIVTEWMGGGSLRQFLTDHFNLLEQNPHIRLKLALDIAKGMNYL 2232
Query 1015 HAQH--YIHRDLAARNVLLDN-------------DRLVKIGDFGLAKAVPEGHEYYRVRE 1059
H +HRDL++RN+LLD+ D KI DFGL++ E +
Sbjct 2233 HGWTPPILHRDLSSRNILLDHNIDPKNPVVSSRQDIKCKISDFGLSRLKME-QASQMTQS 2291
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
G P + APE K SDV+S+G+ L+ELLT S P Q M
Sbjct 2292 VGCIP--YMAPEVFKGDSNSEKSDVYSYGMVLFELLT----SDEP-----------QQDM 2334
Query 1120 TVLRLTELLE-RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+++ L R P P + ++ CW++ RPTF+ +I LK + ++
Sbjct 2335 KPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQIIVHLKEMEDQ 2391
Score = 60.5 bits (145), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 62/255 (24%), Positives = 113/255 (44%), Gaps = 38/255 (15%)
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPEN--IMVTEYVEHGPLDVWLR------RERG 704
+ F ++S++ H ++ G C G E+ +VTE++ G L +L +
Sbjct 2156 VMFQNEVGILSKLRHPNVVQFLGACTAGGEDHHCIVTEWMGGGSLRQFLTDHFNLLEQNP 2215
Query 705 HVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFI------- 755
H+ ++ +A +A ++YL ++H ++ RNILL + +P +
Sbjct 2216 HI----RLKLALDIAKGMNYLHGWTPPILHRDLSSRNILLDHN--IDPKNPVVSSRQDIK 2269
Query 756 -KLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
K+SD GL L E+ V IP++APE G +NS + D + +G L E+
Sbjct 2270 CKISD--FGLSRLKMEQASQMTQSVGCIPYMAPEVFKGDSNSEKS--DVYSYGMVLFELL 2325
Query 809 FDGEAPLQSRSPSEKEHFYQRQ-HRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRD 865
E P Q P + H + +R P P + + + +QC P RP+F+ I+
Sbjct 2326 TSDE-PQQDMKPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQIIVH 2384
Query 866 LTRLQPHNLADVLTV 880
L ++ ++ +V
Sbjct 2385 LKEMEDQGVSSFASV 2399
>sp|Q23915|KINX_DICDI Probable serine/threonine-protein kinase
kinX OS=Dictyostelium discoideum OX=44689 GN=kinX PE=3 SV=2
Length=1094
Score = 99.0 bits (245), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 77/279 (28%), Positives = 130/279 (47%), Gaps = 32/279 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ----EIDILRTLY 955
I ++G G FGKV Y G VA+K + +R ++ EI+ ++
Sbjct 25 ISEIGSGGFGKVFKGEY------LGAPVAIKKIHILPDDPNRVDLEKFLNREIETIKLFT 78
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--FAQQICEGMAY 1013
H ++I++ G E+ G L +V E + G L+ YL SI L L A + M+Y
Sbjct 79 HPNVIQFVGISENNG--ILFIVTELIEGGDLQYYLKNQSIDLPWFLRANIALDVSLAMSY 136
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
LH++ +HRDL + N+L+D + +K+ DFG A+ V E + D+ W +PE +
Sbjct 137 LHSKSIVHRDLKSTNLLVDKNWKIKVCDFGFARIVEEDNNKSMTICGTDN---WMSPEMI 193
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ SD++SFG+ L E++ S+ P ++ L E + R +
Sbjct 194 TGLDYDERSDIFSFGIVLLEII-----SRVKPAPYMRDASFG--------LAEDIVRNQL 240
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+P CP + L NC + + RP+F+ + LK +
Sbjct 241 IPT--DCPESLIDLTFNCCSVDPNNRPSFKEISQTLKQI 277
Score = 58.5 bits (140), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 56/234 (24%), Positives = 102/234 (44%), Gaps = 20/234 (9%)
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
DP+ D+ + +H ++ G+ +VTE +E G L +L+ +
Sbjct 57 DPNRVDLEKFLNREIETIKLFTHPNVIQFVGISENNGILFIVTELIEGGDLQYYLKNQSI 116
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+P + +A ++ A+SYL +K++VH ++ N+L+ + IK+ D G
Sbjct 117 DLPWFLRANIALDVSLAMSYLHSKSIVHRDLKSTNLLVDKNWK-------IKVCD--FGF 167
Query 765 GALSREERVERIP------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE-APLQS 817
+ E+ + + W++PE + G D + FG LLEI + AP
Sbjct 168 ARIVEEDNNKSMTICGTDNWMSPEMITGL--DYDERSDIFSFGIVLLEIISRVKPAPYMR 225
Query 818 RSPSEKEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ R +P CP+ L LT C + +P RPSF+ I + L +++
Sbjct 226 DASFGLAEDIVRNQLIP-TDCPESLIDLTFNCCSVDPNNRPSFKEISQTLKQIK 278
>sp|Q54VC0|Y9865_DICDI Probable serine/threonine-protein kinase
DDB_G0280461 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0280461
PE=3 SV=1
Length=418
Score = 96.3 bits (238), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 84/292 (29%), Positives = 131/292 (45%), Gaps = 40/292 (14%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW---KQEIDILRTLY-- 955
+ +G F KV Y G V VK +K D S W K+EI IL+ L
Sbjct 18 NEFSKGSFAKVYKGSY------YGNPVCVKVIKKDTLIDKES-WVFLKREIGILKNLLNQ 70
Query 956 -HEHIIKYKGCCEDQGEKS--LQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEG 1010
H++II++ G GEK L LV E + G L + L H I + + A+ I EG
Sbjct 71 GHKNIIRFIGI----GEKDSLLFLVTELINGGDLGNILLDHKFHIPWSLRVKIAKDIAEG 126
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
M YLH++ +HRDL + N+LL + +KI DFG AK + + D + +P
Sbjct 127 MEYLHSKQIMHRDLKSNNLLLGRNWTIKICDFGFAKEITIQNPLSMTICGTDE---FMSP 183
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E + ++ Y++D++SFG+ L EL+T + P + I + Q +
Sbjct 184 EVILGIQYSYSADIYSFGMVLLELITRSKLDERLPQNNFD-IDYEELQNKI--------- 233
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182
P +CP E L C + + RP+F +++ L + K + P
Sbjct 234 ------PSECPREFLELSMKCCNYDPNDRPSFTDIVQTLDQLAIKLVKETPD 279
Score = 69.7 bits (169), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 59/239 (25%), Positives = 113/239 (47%), Gaps = 23/239 (10%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
+L++Q H ++ G+ + +VTE + G L L + H+P + ++ +A+ +A
Sbjct 66 NLLNQ-GHKNIIRFIGIGEKDSLLFLVTELINGGDLGNILLDHKFHIPWSLRVKIAKDIA 124
Query 720 SALSYLENKNLVHGNVCGRNILLAR---LGLAE-GTSPFIKLSDPGVGLGALSREERVER 775
+ YL +K ++H ++ N+LL R + + + G + I + +P + + +E
Sbjct 125 EGMEYLHSKQIMHRDLKSNNLLLGRNWTIKICDFGFAKEITIQNP-LSMTICGTDE---- 179
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--EHFYQRQHRL 833
+++PE + G S S D + FG LLE+ + L R P + + Q+++
Sbjct 180 --FMSPEVILGIQYSYSA--DIYSFGMVLLELI--TRSKLDERLPQNNFDIDYEELQNKI 233
Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA-SDPTV 891
P + L+ +C Y+P RPSF I++ L +L ++ PD P S P V
Sbjct 234 PSECPREFLELSMKCCNYDPNDRPSFTDIVQTLDQLA----IKLVKETPDGPYPSTPIV 288
>sp|Q8VCT9|TESK2_MOUSE Dual specificity testis-specific protein
kinase 2 OS=Mus musculus OX=10090 GN=Tesk2 PE=1 SV=1
Length=570
Score = 97.4 bits (241), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 77/282 (27%), Positives = 126/282 (45%), Gaps = 39/282 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G F +V + + +G+ V ALK + +R+ +E+ ++ L H +I+++
Sbjct 64 IGSGFFSEV----FKVRHRASGQ---VMALKMNTLSSNRANLLKEMQLMNRLSHPNILRF 116
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G C QG+ L + EY+ G+L L + + A I G++YLH + H
Sbjct 117 MGVCVHQGQ--LHALTEYINSGNLEQLLDSDLYLPWTVRVKLAYDIAVGLSYLHFKGIFH 174
Query 1022 RDLAARNVLLDNDR---LVKIGDFGLAKAVPE---GHEYYRVREDGDSPVFWYAPECLKE 1075
RDL ++N L+ D + DFGLA+ +P+ G E V SP FW APE L++
Sbjct 175 RDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGREKLAVV---GSP-FWMAPEVLRD 230
Query 1076 YKFYYASDVWSFGVTLYELLT--HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ +DV+S+G+ L E++ D P T+ L A M
Sbjct 231 EPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMV------------- 277
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
CP + L NC + RP+FE + LK + +
Sbjct 278 ----GDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLKEIMSR 315
Score = 60.8 bits (146), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 63/251 (25%), Positives = 104/251 (41%), Gaps = 28/251 (11%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
R GQ + + + L + ++ + LM+++SH ++ GVCV + +TEY+
Sbjct 78 RASGQVMALKMNTLSSNRANL----LKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYI 133
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR------ 744
G L+ L + ++P ++ +A +A LSYL K + H ++ +N L+ R
Sbjct 134 NSGNLEQLLDSDL-YLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYS 192
Query 745 -----LGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
GLAE K+ D +G L+ V W+APE L + D +
Sbjct 193 AVVADFGLAE------KIPDASIGREKLA---VVGSPFWMAPEVL--RDEPYNEKADVFS 241
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQRPS 858
+G L EI +A +E + CP LT C +P RPS
Sbjct 242 YGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVGDCPSDFLQLTFNCCNMDPKLRPS 301
Query 859 FRTILRDLTRL 869
F I + L +
Sbjct 302 FEEIGKTLKEI 312
>sp|A8WYE4|PAR1_CAEBR Serine/threonine-protein kinase par-1 OS=Caenorhabditis
briggsae OX=6238 GN=par-1 PE=3 SV=1
Length=1088
Score = 98.6 bits (244), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 70/208 (34%), Positives = 104/208 (50%), Gaps = 13/208 (6%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDI 950
H K ++ +G+G+F KV L + T G VA+K + K P +E+ I
Sbjct 123 VHVGKYKLLKTIGKGNFAKVKLAKHVIT----GHEVAIKIIDKTALNPSSLQKLFREVKI 178
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICE 1009
++ L H +I+K E E++L LV+EY G + DYL H + + +QI
Sbjct 179 MKQLDHPNIVKLYQVMET--EQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS 236
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ YLH+++ IHRDL A N+LLD D +KI DFG + G++ G P + A
Sbjct 237 AVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFC--GSPP--YAA 292
Query 1070 PECLKEYKFYYAS-DVWSFGVTLYELLT 1096
PE K+ DVWS GV LY L++
Sbjct 293 PELFSGKKYDGPEVDVWSLGVILYTLVS 320
Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 54/236 (23%), Positives = 99/236 (42%), Gaps = 22/236 (9%)
Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K++D + + + + +M Q+ H ++ ++ V +V EY G +
Sbjct 154 VAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVF 213
Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+L H M K A+ Q+ SA+ YL +KN++H ++ N+LL +
Sbjct 214 DYLV---AHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQ-------DMN 263
Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
IK++D G S +++ P+ APE G +D W G +L
Sbjct 264 IKIADFGFS-NTFSLGNKLDTFCGSPPYAAPELF-SGKKYDGPEVDVWSLGV-ILYTLVS 320
Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
G P ++ E +E + ++R+P L + L P +R S I++D
Sbjct 321 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKD 376
>sp|P53670|LIMK2_RAT LIM domain kinase 2 OS=Rattus norvegicus
OX=10116 GN=Limk2 PE=2 SV=1
Length=638
Score = 97.8 bits (242), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 76/281 (27%), Positives = 125/281 (44%), Gaps = 38/281 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+ T+ TG+++ +K L C + + + E+ ++R+L H +++K+
Sbjct 337 LGKGFFGQA----IKVTHKATGKVMVMKEL-IRCDEETQKTFLTEVKVMRSLDHPNVLKF 391
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G +K L L+ EY+ G+L+D+L Q + FA+ I GMAYLH+ IH
Sbjct 392 IGVL--YKDKKLNLLTEYIEGGTLKDFLRNVDPFPWQQKVRFAKGIASGMAYLHSMCIIH 449
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---------------- 1065
RDL + N L+ D+ V + DFGL++ + E + V +
Sbjct 450 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRPPVEKAATKKRTLRKSDRKKRYTVVGN 509
Query 1066 -FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+W APE L + DV+SFG+ L E++ + + L+ G L
Sbjct 510 PYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDF-----GLNVKLFW 564
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + P CP + L C + E RP F L
Sbjct 565 EKFV--------PTDCPPAFFPLAAICCKLEPESRPAFSKL 597
Score = 53.9 bits (128), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 61/248 (25%), Positives = 102/248 (41%), Gaps = 31/248 (13%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+V+K L + F +M + H ++ GV + + ++TEY+E G L +
Sbjct 357 MVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDF 416
Query 699 LRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNIL-------------LA 743
LR P W+ V A+ +AS ++YL + ++H ++ N L L+
Sbjct 417 LRNVD---PFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLS 473
Query 744 RLGLAEGTSPFI-KLSDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWG 799
RL + E P + K + L R++R + W+APE L G S +D +
Sbjct 474 RLIVEERKRPPVEKAATKKRTLRKSDRKKRYTVVGNPYWMAPEMLNG--KSYDETVDVFS 531
Query 800 FGATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854
FG L EI A P + F+++ +P P L + C EP
Sbjct 532 FGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEK--FVPTDCPPAFFPLAAICCKLEPE 589
Query 855 QRPSFRTI 862
RP+F +
Sbjct 590 SRPAFSKL 597
>sp|Q9TW45|PAR1_CAEEL Serine/threonine-protein kinase par-1 OS=Caenorhabditis
elegans OX=6239 GN=par-1 PE=1 SV=1
Length=1192
Score = 98.6 bits (244), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 70/208 (34%), Positives = 104/208 (50%), Gaps = 13/208 (6%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDI 950
H K ++ +G+G+F KV L + T G VA+K + K P +E+ I
Sbjct 165 VHVGKYKLLKTIGKGNFAKVKLAKHVIT----GHEVAIKIIDKTALNPSSLQKLFREVKI 220
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICE 1009
++ L H +I+K E E++L LV+EY G + DYL H + + +QI
Sbjct 221 MKQLDHPNIVKLYQVMET--EQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS 278
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ YLH+++ IHRDL A N+LLD D +KI DFG + G++ G P + A
Sbjct 279 AVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTF--CGSPP--YAA 334
Query 1070 PECLKEYKFYYAS-DVWSFGVTLYELLT 1096
PE K+ DVWS GV LY L++
Sbjct 335 PELFSGKKYDGPEVDVWSLGVILYTLVS 362
Score = 47.8 bits (112), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 54/236 (23%), Positives = 99/236 (42%), Gaps = 22/236 (9%)
Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K++D + + + + +M Q+ H ++ ++ V +V EY G +
Sbjct 196 VAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVF 255
Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+L H M K A+ Q+ SA+ YL +KN++H ++ N+LL +
Sbjct 256 DYLV---AHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQ-------DMN 305
Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
IK++D G S +++ P+ APE G +D W G +L
Sbjct 306 IKIADFGFS-NTFSLGNKLDTFCGSPPYAAPELF-SGKKYDGPEVDVWSLGV-ILYTLVS 362
Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
G P ++ E +E + ++R+P L + L P +R S I++D
Sbjct 363 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKD 418
>sp|B4MR28|PTK7_DROWI Tyrosine-protein kinase-like otk OS=Drosophila
willistoni OX=7260 GN=otk PE=3 SV=1
Length=1059
Score = 98.6 bits (244), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 69/258 (27%), Positives = 120/258 (47%), Gaps = 34/258 (13%)
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
+V VKAL Q +++++D+LR L H+ I++ G C ++ LV+EY G
Sbjct 806 LVMVKALNKVKDEQACQEFRRQLDLLRALSHKGIVRLYGLCREKDPH--YLVLEYTDWGD 863
Query 986 LRDYL------------------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027
L+ +L P + +Q+L A QI GM ++ + HRDLA R
Sbjct 864 LKQFLLATAGKVNTATTATSSTTPLPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATR 923
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
N ++ ++ +VK+ L K EY++ R + P+ W APEC++E ++ SD++S+
Sbjct 924 NCVISSEFIVKVSYPALCKD-KYSREYHKHR-NSLLPIRWLAPECIQEDEYTTKSDIFSY 981
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
GV ++EL +++ P I + Q L+ T + P + +
Sbjct 982 GVVVWELFNQ--ATKLPHEDLTNEQVIEKSQDGTLKWT----------VAESTPESLKEI 1029
Query 1148 MKNCWETEASFRPTFENL 1165
+ +CW RP+F L
Sbjct 1030 LLSCWSVNPKQRPSFSQL 1047
Score = 55.5 bits (132), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 61/258 (24%), Positives = 105/258 (41%), Gaps = 39/258 (15%)
Query 639 VVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V++K L+ + A F L+ +SH + ++G+C + +V EY + G L
Sbjct 807 VMVKALNKVKDEQACQEFRRQLDLLRALSHKGIVRLYGLCREKDPHYLVLEYTDWGDLKQ 866
Query 698 WLRRERGHV--------------PMAWKMV--VAQQLASALSYLENKNLVHGNVCGRNIL 741
+L G V P+ V VA Q+A + + H ++ RN +
Sbjct 867 FLLATAGKVNTATTATSSTTPLPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRNCV 926
Query 742 LARLGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAM 795
+ +S FI K+S P + SRE R I WLAPEC+ + +T
Sbjct 927 I--------SSEFIVKVSYPALCKDKYSREYHKHRNSLLPIRWLAPECIQ--EDEYTTKS 976
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH-----RLPEPSCPQLATLTSQCLT 850
D + +G + E+ F+ L + ++ + Q + E + L + C +
Sbjct 977 DIFSYGVVVWEL-FNQATKLPHEDLTNEQVIEKSQDGTLKWTVAESTPESLKEILLSCWS 1035
Query 851 YEPTQRPSFRTILRDLTR 868
P QRPSF + L++
Sbjct 1036 VNPKQRPSFSQLGAALSK 1053
>sp|Q86AT8|SPKA_DICDI Stress-activated protein kinase alpha OS=Dictyostelium
discoideum OX=44689 GN=spkA-1 PE=1 SV=1
Length=638
Score = 97.8 bits (242), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 80/297 (27%), Positives = 138/297 (46%), Gaps = 25/297 (8%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ + L+ LG G GKV Y G+ VA+K LK+ + +K+E
Sbjct 344 NIINDNELEYTEKLGAGSSGKVYKGLY------RGKEVAIKVLKSMTESKEIEEFKKEFQ 397
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQI 1007
I+ + +H++ + G E L +VME GSL + +S IG + FA +
Sbjct 398 IMSAIRSKHVVHFYGAV---LEPKLCMVMENCSRGSLYHVMDNNSLDIGWERTFRFAIET 454
Query 1008 CEGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
G+ LH +HRDL + N+L+++ +K+ DFGL++ + V+ G
Sbjct 455 VRGIECLHKWDPPIVHRDLKSLNLLVNDKWEIKVCDFGLSRFNTGSNLETLVKMRG---T 511
Query 1066 FWY-APECLKEYKFYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVL 1122
F Y APE +F SDV+S V L+EL+T C + + P +++ L Q
Sbjct 512 FAYCAPEVYYGEQFSGKSDVYSIAVILWELVTRCINGRYERPFSEYKNL------QHDFQ 565
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+ + ++ R P+ CP + L+++CW+ RPT +++ L T+ +Y+
Sbjct 566 IIIQTAKKNLRPTIPNACPESLVSLIQDCWDPNLENRPTCTDILSRLVTIENEYRSN 622
>sp|O54785|LIMK2_MOUSE LIM domain kinase 2 OS=Mus musculus OX=10090
GN=Limk2 PE=1 SV=2
Length=638
Score = 97.4 bits (241), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 77/281 (27%), Positives = 125/281 (44%), Gaps = 38/281 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+ T+ TG+++ +K L C + + + E+ ++R+L H +++K+
Sbjct 337 LGKGFFGQA----IKVTHKATGKVMVMKEL-IRCDEETQKTFLTEVKVMRSLDHPNVLKF 391
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G +K L L+ EY+ G+L+D+L Q + FA+ I GMAYLH+ IH
Sbjct 392 IGVL--YKDKKLNLLTEYIEGGTLKDFLRSVDPFPWQQKVRFAKGISSGMAYLHSMCIIH 449
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE---------YYRVREDGDSPV------- 1065
RDL + N L+ D+ V + DFGL++ + E + R D
Sbjct 450 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRPPVEKATTKKRTLRKSDRKKRYTVVGN 509
Query 1066 -FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+W APE L + DV+SFG+ L E++ + + L+ G L
Sbjct 510 PYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDF-----GLNVKLFW 564
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + P CP + L C + E RP F L
Sbjct 565 EKFV--------PTDCPPAFFPLAAICCKLEPESRPAFSKL 597
Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 60/248 (24%), Positives = 102/248 (41%), Gaps = 31/248 (13%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+V+K L + F +M + H ++ GV + + ++TEY+E G L +
Sbjct 357 MVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDF 416
Query 699 LRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNIL-------------LA 743
LR P W+ V A+ ++S ++YL + ++H ++ N L L+
Sbjct 417 LRSVD---PFPWQQKVRFAKGISSGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLS 473
Query 744 RLGLAEGTSPFI-KLSDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWG 799
RL + E P + K + L R++R + W+APE L G S +D +
Sbjct 474 RLIVEERKRPPVEKATTKKRTLRKSDRKKRYTVVGNPYWMAPEMLNG--KSYDETVDVFS 531
Query 800 FGATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854
FG L EI A P + F+++ +P P L + C EP
Sbjct 532 FGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEK--FVPTDCPPAFFPLAAICCKLEPE 589
Query 855 QRPSFRTI 862
RP+F +
Sbjct 590 SRPAFSKL 597
>sp|P32562|CDC5_YEAST Cell cycle serine/threonine-protein kinase
CDC5/MSD2 OS=Saccharomyces cerevisiae (strain ATCC 204508
/ S288c) OX=559292 GN=CDC5 PE=1 SV=1
Length=705
Score = 97.4 bits (241), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 67/198 (34%), Positives = 104/198 (53%), Gaps = 15/198 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQH-RSGWKQEIDILRTLYHEHII 960
LGEG F + C+ D +GE+ A K + KA + R EI I +++ H +I+
Sbjct 88 LGEGGFAR----CFQ-IKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIV 142
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA-QLLLFAQQICEGMAYLHAQHY 1019
++ C ED + ++ +++E P GSL + L R + ++ F QIC + Y+H++
Sbjct 143 QFIDCFED--DSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRV 200
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL--KEYK 1077
IHRDL N+ D++ +KIGDFGLA + +E R +P + APE L K
Sbjct 201 IHRDLKLGNIFFDSNYNLKIGDFGLAAVL--ANESERKYTICGTPN-YIAPEVLMGKHSG 257
Query 1078 FYYASDVWSFGVTLYELL 1095
+ D+WS GV LY LL
Sbjct 258 HSFEVDIWSLGVMLYALL 275
Score = 45.1 bits (105), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 49/216 (23%), Positives = 90/216 (42%), Gaps = 22/216 (10%)
Query 661 LMSQV----SHTHLAFVHGV-CVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
L+S++ S +H V + C N+ ++ E +G L L+R + +
Sbjct 126 LLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFT 185
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
Q + A+ Y+ ++ ++H ++ NI ++ +K+ D G+ + ER
Sbjct 186 TQ-ICGAIKYMHSRRVIHRDLKLGNIFF-------DSNYNLKIGDFGLAAVLANESERKY 237
Query 775 RI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE-KEHFYQR 829
I ++APE L G + S +D W G L + G+ P Q+R + E R
Sbjct 238 TICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLI-GKPPFQARDVNTIYERIKCR 296
Query 830 QHRLP--EPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
P +P + L L+ +P +RPS I+
Sbjct 297 DFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIM 332
>sp|Q9I9E0|TAOK3_CHICK Serine/threonine-protein kinase TAO3 OS=Gallus
gallus OX=9031 GN=TAOK3 PE=2 SV=2
Length=898
Score = 97.8 bits (242), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 74/203 (36%), Positives = 104/203 (51%), Gaps = 23/203 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956
+ ++G G FG V Y TN T E+VAVK + + G Q W+ +E+ L+ L H
Sbjct 27 LHEIGHGSFGAV----YFATNSHTNEVVAVKKM-SYSGKQTNEKWQDIIKEVKFLQQLKH 81
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014
+ I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL
Sbjct 82 PNTIEYKGCY--LKEHTAWLVMEYC-LGSASDMLEVHKKPLQEVEIAAITHGALQGLAYL 138
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071
H+ IHRD+ A N+LL VK+ DFG A V + + +P +W APE
Sbjct 139 HSHCKIHRDIKAGNILLTEPGQVKLADFGSASIVSPANSFV------GTP-YWMAPEVIL 191
Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094
+ E ++ DVWS G+T EL
Sbjct 192 AMDEGQYDGKVDVWSLGITCIEL 214
>sp|Q55EI8|Y9956_DICDI Probable serine/threonine-protein kinase
DDB_G0268876 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0268876
PE=3 SV=1
Length=1385
Score = 98.2 bits (243), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 79/260 (30%), Positives = 121/260 (47%), Gaps = 25/260 (10%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
G +AVK + + E I+ L H++I+ G G+ + LV +Y
Sbjct 779 GYEIAVKQFNEEELGFSEREFHSEATIMSVLRHDNIVHCVGGSAQPGK--MYLVCDYYSR 836
Query 984 GSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
GSL + + L A+++ A Q+ +GM YLH+ IHRDL N+L+D D ++I D
Sbjct 837 GSLYSVITANICPLSNARIVHLALQVAKGMNYLHSLGIIHRDLKPGNLLIDQDWNIRISD 896
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDS 1100
FGL++ V R+ + +P + A E LK Y +DV+SF L+E C S
Sbjct 897 FGLSRVVDN-----RMTKTVGTPCYM-AVEVLKGLTDYSQQADVYSFAFVLWE----CIS 946
Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
Q P F ++ I+ +LE R P PD C E L+ CW + RP
Sbjct 947 RQIPYKDFAQIQWISM----------VLEDSFRPPIPDSCLPEFRDLITMCWTSNPDDRP 996
Query 1161 TFENLIPILKTVHEKYQGQA 1180
+F+ +I L+ + K Q Q
Sbjct 997 SFQQIITYLENLRLKMQDQG 1016
Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 55/233 (24%), Positives = 102/233 (44%), Gaps = 17/233 (7%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F+ A++MS + H ++ G + + +V +Y G L + + A + +
Sbjct 799 FHSEATIMSVLRHDNIVHCVGGSAQPGKMYLVCDYYSRGSLYSVITANICPLSNARIVHL 858
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
A Q+A ++YL + ++H ++ N+L+ + I++SD G+ +R +
Sbjct 859 ALQVAKGMNYLHSLGIIHRDLKPGNLLIDQ-------DWNIRISDFGLSRVVDNRMTKTV 911
Query 775 RIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE-KEHFYQRQHR 832
P ++A E L G + S D + F L E C + P + + + + R
Sbjct 912 GTPCYMAVEVLKGLTD-YSQQADVYSFAFVLWE-CISRQIPYKDFAQIQWISMVLEDSFR 969
Query 833 LPEP-SC-PQLATLTSQCLTYEPTQRPSFRTILRDLT----RLQPHNLADVLT 879
P P SC P+ L + C T P RPSF+ I+ L ++Q + +LT
Sbjct 970 PPIPDSCLPEFRDLITMCWTSNPDDRPSFQQIITYLENLRLKMQDQGIYQILT 1022
>sp|Q0WRY5|PBL7_ARATH Probable serine/threonine-protein kinase
PBL7 OS=Arabidopsis thaliana OX=3702 GN=PBL7 PE=1 SV=1
Length=378
Score = 94.7 bits (234), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 77/212 (36%), Positives = 109/212 (51%), Gaps = 19/212 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG+V Y T + A+K L + G Q + E+ +L L+H +++
Sbjct 79 IGEGGFGRV----YKGYLASTSQTAAIKQLDHN-GLQGNREFLVEVLMLSLLHHPNLVNL 133
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017
G C D G++ L LV EY+PLGSL D+L S G L + A +G+ YLH +
Sbjct 134 IGYCAD-GDQRL-LVYEYMPLGSLEDHLHDISPGKQPLDWNTRMKIAAGAAKGLEYLHDK 191
Query 1018 HY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
I+RDL N+LLD+D K+ DFGLAK P G + + V + APE
Sbjct 192 TMPPVIYRDLKCSNILLDDDYFPKLSDFGLAKLGPVGDKSH-VSTRVMGTYGYCAPEYAM 250
Query 1075 EYKFYYASDVWSFGVTLYELLT---HCDSSQS 1103
+ SDV+SFGV L E++T DSS+S
Sbjct 251 TGQLTLKSDVYSFGVVLLEIITGRKAIDSSRS 282
Score = 54.3 bits (129), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 63/237 (27%), Positives = 99/237 (42%), Gaps = 35/237 (15%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KMVVAQQ 717
++S + H +L + G C G + ++V EY+ G L+ L G P+ W +M +A
Sbjct 121 MLSLLHHPNLVNLIGYCADGDQRLLVYEYMPLGSLEDHLHDISPGKQPLDWNTRMKIAAG 180
Query 718 LASALSYLENKNL---VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERV 773
A L YL +K + ++ ++ NILL F KLSD G+ LG + + V
Sbjct 181 AAKGLEYLHDKTMPPVIYRDLKCSNILL-------DDDYFPKLSDFGLAKLGPVGDKSHV 233
Query 774 E-RIPWLAPECLPGGANS--LSTAMDKWGFGATLLEICFDGEAPLQSRSPSE-------- 822
R+ C P A + L+ D + FG LLEI +A SRS E
Sbjct 234 STRVMGTYGYCAPEYAMTGQLTLKSDVYSFGVVLLEIITGRKAIDSSRSTGEQNLVAWAR 293
Query 823 -----KEHFYQR-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ F Q Q + P Q + + C+ +P RP ++ L+ L
Sbjct 294 PLFKDRRKFSQMADPMLQGQYPPRGLYQALAVAAMCVQEQPNLRPLIADVVTALSYL 350
>sp|Q14680|MELK_HUMAN Maternal embryonic leucine zipper kinase
OS=Homo sapiens OX=9606 GN=MELK PE=1 SV=3
Length=651
Score = 97.4 bits (241), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 71/204 (35%), Positives = 108/204 (53%), Gaps = 12/204 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+Y + +G G F KV L C+ T GEMVA+K + + K EI+ L+ L
Sbjct 9 KYYELHETIGTGGFAKVKLACHILT----GEMVAIKIMDKNTLGSDLPRIKTEIEALKNL 64
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAY 1013
H+HI + E + + +V+EY P G L DY+ + + + + +QI +AY
Sbjct 65 RHQHICQLYHVLETANK--IFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAY 122
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+H+Q Y HRDL N+L D +K+ DFGL A P+G++ Y ++ S + + APE L
Sbjct 123 VHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC-AKPKGNKDYHLQTCCGS-LAYAAPE-L 179
Query 1074 KEYKFYYAS--DVWSFGVTLYELL 1095
+ K Y S DVWS G+ LY L+
Sbjct 180 IQGKSYLGSEADVWSMGILLYVLM 203
>sp|Q27324|RYK1_DROME Tyrosine-protein kinase Drl OS=Drosophila
melanogaster OX=7227 GN=drl PE=2 SV=1
Length=610
Score = 97.1 bits (240), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 94/390 (24%), Positives = 163/390 (42%), Gaps = 58/390 (15%)
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQ--HRLPEPSCPQLATLTSQCLTYEPTQRPSF 859
+TL+ I + + P R PS H + RLP S +T + T P++
Sbjct 258 STLILIAYCAKGP-SKRHPSNGVHLIKTSSFQRLPTIS----STAHNSIYVCPSTITPTY 312
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY----LKKIRD-----LGEGHFGK 910
T+ R + +P F++R ++K R + EG+FG+
Sbjct 313 ATLTRPFREYE----------------HEPEEFNRRLQELTVQKCRVRLSCLVQEGNFGR 356
Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970
+ Y+ + V VK + + QE +L H +++ G +
Sbjct 357 IYRGTYNDCQE-----VLVKTVAQHASQLQVNLLLQESMMLYEASHPNVLSVLGISIEDY 411
Query 971 EKSLQLVMEYVPLGSLRDYL--PRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
L + +L+ +L P + S+ Q +L Q+ M +LH IH+D+AA
Sbjct 412 ATPFVLYAATGSVRNLKSFLQDPSYARSVTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAA 471
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD-SPVFWYAPECLKEYKFYYASDVW 1085
RN ++D+ VK+ D L++ + G Y DG+ P+ W + E L++ + SDVW
Sbjct 472 RNCVIDDQLRVKLTDSALSRDLFPGD--YNSLGDGEYRPIKWLSLEALQKSHYNEGSDVW 529
Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
SFGV ++E+ T L + ++ + L+ G RL +P CP E++
Sbjct 530 SFGVLMWEMCT--------------LGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELF 575
Query 1146 HLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+M CW + + RP+F L L H +
Sbjct 576 TIMAYCWASMPAERPSFSQLQICLSEFHTQ 605
Score = 64.3 bits (155), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 47/167 (28%), Positives = 76/167 (46%), Gaps = 27/167 (16%)
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
V +++ QLA A+ +L N ++H ++ RN ++ +KL+D
Sbjct 440 VTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVI-------DDQLRVKLTD-----S 487
Query 766 ALSRE-----------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
ALSR+ I WL+ E L + + D W FG + E+C G+ P
Sbjct 488 ALSRDLFPGDYNSLGDGEYRPIKWLSLEALQ--KSHYNEGSDVWSFGVLMWEMCTLGKLP 545
Query 815 LQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
P E EH+ + +RL +P +CP +L T+ + C P +RPSF
Sbjct 546 YAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 592
>sp|Q86HG9|Y9871_DICDI Probable serine/threonine-protein kinase
DDB_G0271682 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0271682
PE=3 SV=2
Length=1024
Score = 97.8 bits (242), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 78/282 (28%), Positives = 129/282 (46%), Gaps = 38/282 (13%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEH 958
I+ +G G G+V Y + G VAVK + K+ + +++E+ IL+ L H +
Sbjct 363 IKKIGSGACGEVCQY------EWKGTPVAVKTIFKSLLRKDKKEEFEKEVSILKCLRHPN 416
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH 1015
++ + G C G +L ++ EY+ GSLRD L + + L+ + + +GM YLH
Sbjct 417 VVLFMGTCLLNG--NLAIITEYLNRGSLRDVLTTMNKSELSLSVKVKMLIDVAQGMNYLH 474
Query 1016 AQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRDL + N+L+DN+ VK+ DFGL++ + G G + W APE
Sbjct 475 TYSPPIIHRDLKSLNLLVDNNFNVKVSDFGLSRFISGGIGSSAKTFCG--TLSWIAPEVF 532
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ DV+SFG+ L+E+LTH P+ + + ++
Sbjct 533 NGSGYTTKVDVYSFGIVLWEILTH-----KQPSGNISATSLGHPEL-------------- 573
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
P CP L+K C RP F ++ LK ++ +
Sbjct 574 ---PSNCPQSFSDLIKECCNRNPDQRPNFSQILLKLKLMYNQ 612
Score = 64.3 bits (155), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 55/218 (25%), Positives = 94/218 (43%), Gaps = 27/218 (12%)
Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQ 717
S++ + H ++ G C+ ++TEY+ G L DV + + ++ K+ +
Sbjct 406 VSILKCLRHPNVVLFMGTCLLNGNLAIITEYLNRGSLRDVLTTMNKSELSLSVKVKMLID 465
Query 718 LASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGALSR 769
+A ++YL + ++H + L L L + +K+SD G+ G+G+ S
Sbjct 466 VAQGMNYLHTYSPPIIHRD-------LKSLNLLVDNNFNVKVSDFGLSRFISGGIGS-SA 517
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
+ + W+APE G +T +D + FG L EI L + PS
Sbjct 518 KTFCGTLSWIAPEVFNGSG--YTTKVDVYSFGIVLWEI-------LTHKQPSGNISATSL 568
Query 830 QHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866
H +CPQ + L +C P QRP+F IL L
Sbjct 569 GHPELPSNCPQSFSDLIKECCNRNPDQRPNFSQILLKL 606
Score = 40.8 bits (94), Expect = 0.083, Method: Compositional matrix adjust.
Identities = 32/140 (23%), Positives = 65/140 (46%), Gaps = 19/140 (14%)
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP-ECLKEYKFYYASDVWSFGVTL 1091
N+ +K+ DFGL++ + +E G+ F Y+P E L + SD++S + L
Sbjct 887 NEIKIKVHDFGLSRFNTQENEESLKEIKGN---FLYSPPELLSLNTYSNKSDIYSLSIVL 943
Query 1092 YELLTHC-DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP-RP---DKCPCEVYH 1146
YEL C + P ++T+ +++ + +L RP + P E+
Sbjct 944 YELFETCLTKTYKKPYH----------EVTLDFDFQIIHKTSKLNLRPTISNNMPNEISK 993
Query 1147 LMKNCWETEASFRPTFENLI 1166
+++ W +++ RP+ + +I
Sbjct 994 ILQQGWFSDSVLRPSLDTII 1013
>sp|Q8RWW0|ALE2_ARATH Receptor-like serine/threonine-protein kinase
ALE2 OS=Arabidopsis thaliana OX=3702 GN=ALE2 PE=1 SV=1
Length=744
Score = 97.4 bits (241), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 74/200 (37%), Positives = 102/200 (51%), Gaps = 15/200 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LGEG FG+V + DGT VAVK L D + R + E+++L L+H +++
Sbjct 353 RVLGEGGFGRVYQGSME---DGT--EVAVKLLTRDNQNRDRE-FIAEVEMLSRLHHRNLV 406
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ--- 1017
K G C + ++ L+ E V GS+ +L ++ L A G+AYLH
Sbjct 407 KLIGICIEG--RTRCLIYELVHNGSVESHLHEGTLDWDARLKIALGAARGLAYLHEDSNP 464
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKEY 1076
IHRD A NVLL++D K+ DFGLA+ EG ++ R G F Y APE
Sbjct 465 RVIHRDFKASNVLLEDDFTPKVSDFGLAREATEGSQHISTRVMG---TFGYVAPEYAMTG 521
Query 1077 KFYYASDVWSFGVTLYELLT 1096
SDV+S+GV L ELLT
Sbjct 522 HLLVKSDVYSYGVVLLELLT 541
>sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapiens OX=9606
GN=LIMK2 PE=1 SV=1
Length=638
Score = 97.1 bits (240), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 76/281 (27%), Positives = 124/281 (44%), Gaps = 38/281 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+ T+ TG+++ +K L C + + + E+ ++R+L H +++K+
Sbjct 337 LGKGFFGQA----IKVTHKATGKVMVMKEL-IRCDEETQKTFLTEVKVMRSLDHPNVLKF 391
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G +K L L+ EY+ G+L+D+L Q + FA+ I GMAYLH+ IH
Sbjct 392 IGVL--YKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAYLHSMCIIH 449
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE---------YYRVREDGDSPV------- 1065
RDL + N L+ D+ V + DFGL++ + E + R D
Sbjct 450 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGN 509
Query 1066 -FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+W APE L + D++SFG+ L E++ + + L+ G L
Sbjct 510 PYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDF-----GLNVKLFW 564
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + P CP + L C E RP F L
Sbjct 565 EKFV--------PTDCPPAFFPLAAICCRLEPESRPAFSKL 597
Score = 53.9 bits (128), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 61/248 (25%), Positives = 102/248 (41%), Gaps = 31/248 (13%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+V+K L + F +M + H ++ GV + + ++TEY+E G L +
Sbjct 357 MVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDF 416
Query 699 LRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNIL-------------LA 743
L R P W+ V A+ +AS ++YL + ++H ++ N L L+
Sbjct 417 L---RSMDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLS 473
Query 744 RLGLAE-GTSPFIKLSDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWG 799
RL + E +P K + L R++R + W+APE L G S +D +
Sbjct 474 RLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWMAPEMLNG--KSYDETVDIFS 531
Query 800 FGATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854
FG L EI A P + F+++ +P P L + C EP
Sbjct 532 FGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEK--FVPTDCPPAFFPLAAICCRLEPE 589
Query 855 QRPSFRTI 862
RP+F +
Sbjct 590 SRPAFSKL 597
>sp|Q9ZNQ8|PERK4_ARATH Proline-rich receptor-like protein kinase
PERK4 OS=Arabidopsis thaliana OX=3702 GN=PERK4 PE=1 SV=1
Length=633
Score = 96.7 bits (239), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 69/201 (34%), Positives = 104/201 (52%), Gaps = 18/201 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V +G+ VAVK+LKA G R ++ E+DI+ ++H +++
Sbjct 290 LGQGGFGYVHKGVLP-----SGKEVAVKSLKAGSGQGERE-FQAEVDIISRVHHRYLVSL 343
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL---LLFAQQICEGMAYLHAQ-- 1017
G C G++ LV E+VP +L +L ++ + + L A +G+AYLH
Sbjct 344 VGYCIADGQR--MLVYEFVPNKTLEYHLHGKNLPVMEFSTRLRIALGAAKGLAYLHEDCH 401
Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075
IHRD+ + N+LLD + + DFGLAK + + + R G F Y APE
Sbjct 402 PRIIHRDIKSANILLDFNFDAMVADFGLAKLTSDNNTHVSTRVMG---TFGYLAPEYASS 458
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
K SDV+S+GV L EL+T
Sbjct 459 GKLTEKSDVFSYGVMLLELIT 479
Score = 38.5 bits (88), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 59/260 (23%), Positives = 98/260 (38%), Gaps = 44/260 (17%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K L F ++S+V H +L + G C+ + ++V E+V + L+
Sbjct 309 VAVKSLKAGSGQGEREFQAEVDIISRVHHRYLVSLVGYCIADGQRMLVYEFVPNKTLEYH 368
Query 699 LRRERGHV-PMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILL--------ARLG 746
L + V + ++ +A A L+YL ++H ++ NILL A G
Sbjct 369 LHGKNLPVMEFSTRLRIALGAAKGLAYLHEDCHPRIIHRDIKSANILLDFNFDAMVADFG 428
Query 747 LAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
LA+ TS V +G +LAPE G L+ D + +G LLE
Sbjct 429 LAKLTSDNNTHVSTRV-MGTFG---------YLAPEYASSG--KLTEKSDVFSYGVMLLE 476
Query 807 IC----------------FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ----LATLTS 846
+ D PL +R+ + RL PQ + T +
Sbjct 477 LITGKRPVDNSITMDDTLVDWARPLMARALEDGNFNELADARLEGNYNPQEMARMVTCAA 536
Query 847 QCLTYEPTQRPSFRTILRDL 866
+ + +RP I+R L
Sbjct 537 ASIRHSGRKRPKMSQIVRAL 556
>sp|Q9CAL8|PEK13_ARATH Proline-rich receptor-like protein kinase
PERK13 OS=Arabidopsis thaliana OX=3702 GN=PERK13 PE=1 SV=1
Length=710
Score = 97.1 bits (240), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 72/201 (36%), Positives = 102/201 (51%), Gaps = 18/201 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG C G++VAVK LK G R +K E++I+ ++H H++
Sbjct 359 LGEGGFG-----CVYKGKLNDGKLVAVKQLKVGSGQGDRE-FKAEVEIISRVHHRHLVSL 412
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
G C E+ L+ EYVP +L +L R + A+ + A +G+AYLH
Sbjct 413 VGYCIADSER--LLIYEYVPNQTLEHHLHGKGRPVLEWARRVRIAIGSAKGLAYLHEDCH 470
Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075
IHRD+ + N+LLD++ ++ DFGLAK + R G F Y APE +
Sbjct 471 PKIIHRDIKSANILLDDEFEAQVADFGLAKLNDSTQTHVSTRVMG---TFGYLAPEYAQS 527
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
K SDV+SFGV L EL+T
Sbjct 528 GKLTDRSDVFSFGVVLLELIT 548
Score = 43.9 bits (102), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 50/184 (27%), Positives = 77/184 (42%), Gaps = 37/184 (20%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F ++S+V H HL + G C+ E +++ EYV + L+ L +G + W ++
Sbjct 394 FKAEVEIISRVHHRHLVSLVGYCIADSERLLIYEYVPNQTLEHHL-HGKGRPVLEWARRV 452
Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPG 761
+A A L+YL ++H ++ NILL A GLA KL+D
Sbjct 453 RIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDDEFEAQVADFGLA-------KLND-- 503
Query 762 VGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
S + V +LAPE G L+ D + FG LLE+ G P+
Sbjct 504 ------STQTHVSTRVMGTFGYLAPEYAQSG--KLTDRSDVFSFGVVLLEL-ITGRKPVD 554
Query 817 SRSP 820
P
Sbjct 555 QYQP 558
>sp|F1QGZ6|MELK_DANRE Maternal embryonic leucine zipper kinase
OS=Danio rerio OX=7955 GN=melk PE=2 SV=1
Length=676
Score = 96.7 bits (239), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 73/197 (37%), Positives = 105/197 (53%), Gaps = 14/197 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G F KV L + TGE VA+K + K D G K EI+ ++ L H+H+ +
Sbjct 19 IGSGGFAKVKL----GRHKLTGEKVAIKIMEKKDLG-DDLPRVKIEIEAMKNLSHQHVCR 73
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
E + + +V+EY P G L DY+ + + + +F +QI +AY+H+Q Y
Sbjct 74 LYHVIETTSK--IYMVLEYCPGGELFDYIIAKDRLSEEETRVFFRQIISALAYVHSQGYA 131
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDL N+L+D D +K+ DFGL A P+G + + SP + APE L + K Y
Sbjct 132 HRDLKPENLLIDEDHNLKLIDFGLC-AKPKGGLGFELLTCCGSPAY-AAPE-LIQGKAYI 188
Query 1081 AS--DVWSFGVTLYELL 1095
S DVWS GV LY LL
Sbjct 189 GSEADVWSMGVLLYALL 205
>sp|Q10407|MKH1_SCHPO MAP kinase kinase kinase mkh1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=mkh1
PE=3 SV=1
Length=1116
Score = 97.4 bits (241), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 73/216 (34%), Positives = 112/216 (52%), Gaps = 41/216 (19%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG------------WKQEIDI 950
+G G +GKV L N TGE++AVK ++ PQ +G EI +
Sbjct 831 IGNGTYGKVFL----AMNINTGELIAVKQVEI---PQTINGRHDQLRKDIVDSINAEISM 883
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS----LRDYLPRHSIGLAQLLLF-AQ 1005
+ L H +I++Y G ++ E + + +EYV GS LR+Y P QL+ F ++
Sbjct 884 IADLDHLNIVQYLGF--EKTETDISIFLEYVSGGSIGRCLRNYGPFEE----QLVRFVSR 937
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD--- 1062
Q+ G++YLH++ IHRDL A N+L+D D + KI DFG++K H D +
Sbjct 938 QVLYGLSYLHSKGIIHRDLKADNLLIDFDGVCKISDFGISK-----HSDNVYDNDANLSM 992
Query 1063 -SPVFWYAPECL-KEYKFYYAS-DVWSFGVTLYELL 1095
+FW APE + +++ Y A DVWS G + E+L
Sbjct 993 QGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEML 1028
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 54/240 (23%), Positives = 94/240 (39%), Gaps = 38/240 (16%)
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D DI + S+++ + H ++ G + + EYV G + LR
Sbjct 867 DQLRKDIVDSINAEISMIADLDHLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLR---N 923
Query 705 HVPMAWKMV--VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ P ++V V++Q+ LSYL +K ++H ++ N+L+ G+ K+SD G+
Sbjct 924 YGPFEEQLVRFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDFDGVC-------KISDFGI 976
Query 763 GLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
+ + + I W+APE + S +D W G +LE+ L
Sbjct 977 SKHSDNVYDNDANLSMQGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEM-------LA 1029
Query 817 SRSPSEKEHFYQRQHRL-------PEPS------CPQLATLTSQCLTYEPTQRPSFRTIL 863
R P + Q +L P PS P+ + C T RP+ +L
Sbjct 1030 GRRPWSTDEAIQAMFKLGTEKKAPPIPSELVSQVSPEAIQFLNACFTVNADVRPTAEELL 1089
>sp|Q6DD27|TAOK3_XENLA Serine/threonine-protein kinase TAO3 OS=Xenopus
laevis OX=8355 GN=taok3 PE=2 SV=1
Length=896
Score = 97.4 bits (241), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 85/265 (32%), Positives = 125/265 (47%), Gaps = 40/265 (15%)
Query 878 LTVNPDSP----ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933
L +PD+ DP +R + ++G G FG V Y TN T E+VAVK +
Sbjct 5 LVKDPDNADLFCKEDP----ERIFVDLHEIGHGSFGAV----YFATNSTTNEIVAVKKM- 55
Query 934 ADCGPQHRSGWK---QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
+ G Q W+ +E+ L+ L H + I+YKGC + + LVMEY LGS D L
Sbjct 56 SYSGKQMNEKWQDIIKEVKFLQQLKHPNTIEYKGCY--LKDHTAWLVMEYC-LGSASDLL 112
Query 991 PRHSIGLAQLLLFA--QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
H L ++ + A +G+AYLH+ + IHRD+ A N+LL VK+ DFG A
Sbjct 113 EVHKKPLQEVEIAAITHGALQGLAYLHSHNMIHRDIKAGNILLTEPGQVKLADFGSASKS 172
Query 1049 PEGHEYYRVREDGDSPVFWYAPE---CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + +P +W APE + E ++ D+WS G+T EL + + PP
Sbjct 173 SPANSFV------GTP-YWMAPEVILAMDEGQYDGKIDIWSLGITCIEL-----AERKPP 220
Query 1106 ----TKFLELIGIAQGQMTVLRLTE 1126
L IAQ + L+ E
Sbjct 221 LFNMNAMSALYHIAQNESPTLQSNE 245
Score = 36.6 bits (83), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 8/88 (9%)
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781
L+YL + N++H ++ NILL G +KL+D G + V W+AP
Sbjct 135 LAYLHSHNMIHRDIKAGNILLTEPGQ-------VKLADFGSASKSSPANSFVGTPYWMAP 187
Query 782 EC-LPGGANSLSTAMDKWGFGATLLEIC 808
E L +D W G T +E+
Sbjct 188 EVILAMDEGQYDGKIDIWSLGITCIELA 215
>sp|Q8H186|PBL1_ARATH Probable serine/threonine-protein kinase
PBL1 OS=Arabidopsis thaliana OX=3702 GN=PBL1 PE=1 SV=1
Length=389
Score = 94.4 bits (233), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 92/288 (32%), Positives = 135/288 (47%), Gaps = 31/288 (11%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+GEG FG V D PT +G ++AVK L D HR W EI+ L L H
Sbjct 67 VGEGGFGCVFRGWLDETTLTPTKSSSGLVIAVKRLNPDGFQGHRE-WLTEINYLGQLSHP 125
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSL---------RDYLPRHSIGLAQLLLFAQQIC 1008
+++K G C + ++ LV E++ GSL +D+ P I ++ L A
Sbjct 126 NLVKLIGYCLEDEQR--LLVYEFMHKGSLENHLFANGNKDFKPLSWILRIKVALDA---A 180
Query 1009 EGMAYLHAQ--HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE-YYRVREDGDSPV 1065
+G+A+LH+ I+RD+ A N+LLD+D K+ DFGLA+ P G + Y R G
Sbjct 181 KGLAFLHSDPVKVIYRDIKASNILLDSDFNAKLSDFGLARDGPMGEQSYVSTRVMG---T 237
Query 1066 FWY-APECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR 1123
F Y APE + SDV+SFGV L ELL + + P K L+ A+ +T R
Sbjct 238 FGYAAPEYVSTGHLNARSDVYSFGVVLLELLCGRQALDHNRPAKEQNLVDWARPYLTSRR 297
Query 1124 LTELL--ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
L+ R +P+ + + C E RPT + ++ L
Sbjct 298 KVLLIVDTRLNSQYKPEGA-VRLASIAVQCLSFEPKSRPTMDQVVRAL 344
Score = 65.1 bits (157), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 69/280 (25%), Positives = 124/280 (44%), Gaps = 44/280 (16%)
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
DE L P + L + +K L+P + + + Q+SH +L + G C+ +
Sbjct 81 DETTLTPTKS-SSGLVIAVKRLNPDGFQGHREWLTEINYLGQLSHPNLVKLIGYCLEDEQ 139
Query 683 NIMVTEYVEHGPLD--VWLRRERGHVPMAW--KMVVAQQLASALSYLENK--NLVHGNVC 736
++V E++ G L+ ++ + P++W ++ VA A L++L + +++ ++
Sbjct 140 RLLVYEFMHKGSLENHLFANGNKDFKPLSWILRIKVALDAAKGLAFLHSDPVKVIYRDIK 199
Query 737 GRNILLARLGLAEGTSPF-IKLSDPGVGL-GALSREERVER-----IPWLAPECLPGGAN 789
NILL S F KLSD G+ G + + V + APE + G
Sbjct 200 ASNILL--------DSDFNAKLSDFGLARDGPMGEQSYVSTRVMGTFGYAAPEYVSTG-- 249
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-------HFYQRQHRL--------- 833
L+ D + FG LLE+ +A +R E+ + R+ L
Sbjct 250 HLNARSDVYSFGVVLLELLCGRQALDHNRPAKEQNLVDWARPYLTSRRKVLLIVDTRLNS 309
Query 834 ---PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
PE + +LA++ QCL++EP RP+ ++R L +LQ
Sbjct 310 QYKPEGAV-RLASIAVQCLSFEPKSRPTMDQVVRALVQLQ 348
>sp|A9RVK2|M3K1B_PHYPA Mitogen-activated protein kinase kinase
kinase 1b OS=Physcomitrium patens OX=3218 GN=MEKK1b PE=2 SV=2
Length=764
Score = 97.1 bits (240), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 77/270 (29%), Positives = 122/270 (45%), Gaps = 33/270 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQ---EIDILRTLYHEH 958
+G G FG V Y+ D G AVK + D G + KQ EI +L + H +
Sbjct 437 IGSGTFGSV----YEGI-DNNGMFFAVKEVSLKDQGKVGQEAIKQLEHEIALLSDIQHPN 491
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I++Y G D ++ L + +E V GSL ++ Q+ + +QI G+ YLH +
Sbjct 492 IVQYLGTERD--DEKLYIFLELVSKGSLASLYKKYYFVYDQVRAYTKQILSGLKYLHDRK 549
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ N+L+D + +VK+ DFG+AK V + + + W APE + +
Sbjct 550 IIHRDIKCANILVDTNGVVKLADFGMAKQV----DKLGLLKSFMGSAHWMAPEVVNPKRQ 605
Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ-GQMTVLRLTELLERGERLPR 1136
Y + +D+WS G T+ E+ T G A G++ + + GE
Sbjct 606 YNFLADIWSLGCTVLEMAT----------------GDAPFGELECHSVLWKVGNGEGPLI 649
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
PD E+ + C E RPT + L+
Sbjct 650 PDDLEDEMKDFISKCLEVTVGNRPTCDMLL 679
Score = 41.2 bits (95), Expect = 0.077, Method: Compositional matrix adjust.
Identities = 57/228 (25%), Positives = 99/228 (43%), Gaps = 42/228 (18%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
+G GT +VYEG ++ +G M V +D+G+ + +K L+ H+IAL
Sbjct 437 IGSGTFGSVYEG---IDNNG------MFFAVKEVSLKDQGKVGQEAIKQLE---HEIAL- 483
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
+S + H ++ G + + E V G L ++ + V
Sbjct 484 -------LSDIQHPNIVQYLGTERDDEKLYIFLELVSKGSLASLYKKYY----FVYDQVR 532
Query 715 A--QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-----LGAL 767
A +Q+ S L YL ++ ++H ++ NIL+ G+ +KL+D G+ LG L
Sbjct 533 AYTKQILSGLKYLHDRKIIHRDIKCANILVDTNGV-------VKLADFGMAKQVDKLGLL 585
Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
+ + W+APE + + D W G T+LE+ G+AP
Sbjct 586 --KSFMGSAHWMAPEVV-NPKRQYNFLADIWSLGCTVLEMA-TGDAPF 629
>sp|Q32L23|LIMK2_BOVIN LIM domain kinase 2 OS=Bos taurus OX=9913
GN=LIMK2 PE=2 SV=1
Length=638
Score = 96.7 bits (239), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 76/281 (27%), Positives = 125/281 (44%), Gaps = 38/281 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+ T+ TG+++ + L C + + + E+ ++R+L H +++K+
Sbjct 337 LGKGFFGQA----IKVTHKATGKVMVMNEL-IRCDEETQKTFLTEVKVMRSLDHPNVLKF 391
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G +K L L+ EY+ G+L+D+L Q + FA+ I GMAYLH+ IH
Sbjct 392 IGVL--YKDKKLNLLTEYIEGGTLKDFLRNVDPFPWQQKVRFAKGIASGMAYLHSMCIIH 449
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE---------YYRVREDGDSPV------- 1065
RDL + N L+ D+ V + DFGL++ + E + R D
Sbjct 450 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKKPPVEKATTKKRTLRKSDRKKRYTVVGN 509
Query 1066 -FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+W APE L + DV+SFG+ L E++ + + L+ G L
Sbjct 510 PYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDF-----GLNVKLFW 564
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + P++CP + L C E RP F L
Sbjct 565 EKFV--------PEECPPAFFPLAAICCRLEPESRPAFSKL 597
Score = 54.7 bits (130), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 61/248 (25%), Positives = 102/248 (41%), Gaps = 31/248 (13%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+V+ L + F +M + H ++ GV + + ++TEY+E G L +
Sbjct 357 MVMNELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDF 416
Query 699 LRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNIL-------------LA 743
LR P W+ V A+ +AS ++YL + ++H ++ N L L+
Sbjct 417 LRNVD---PFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLS 473
Query 744 RLGLAEGTSPFI-KLSDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWG 799
RL + E P + K + L R++R + W+APE L G S +D +
Sbjct 474 RLIVEERKKPPVEKATTKKRTLRKSDRKKRYTVVGNPYWMAPEMLNG--KSYDETVDVFS 531
Query 800 FGATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854
FG L EI A P + F+++ +PE P L + C EP
Sbjct 532 FGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEK--FVPEECPPAFFPLAAICCRLEPE 589
Query 855 QRPSFRTI 862
RP+F +
Sbjct 590 SRPAFSKL 597
>sp|A6ZU08|TOS3_YEAS7 Serine/threonine-protein kinase TOS3 OS=Saccharomyces
cerevisiae (strain YJM789) OX=307796 GN=TOS3 PE=3
SV=1
Length=560
Score = 95.9 bits (237), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 70/224 (31%), Positives = 108/224 (48%), Gaps = 40/224 (18%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW-----------KQEIDIL 951
LG G +GKV L + GTG +VA+K L + RSG+ QEI+++
Sbjct 56 LGNGQYGKVKL----ARDLGTGALVAIKILNRF---EKRSGYSLQLKVENPRVNQEIEVM 108
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA----QLLLFAQQ- 1006
+ +HE++++ D + LV+EY G ++ + P + + + +L F Q
Sbjct 109 KRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVK-WCPENKMEIKAVGPSILTFQQSR 167
Query 1007 -----ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG-------HEY 1054
+ G+ YLH+Q HRD+ N+L+ ++ VKI DFG+A + G HE
Sbjct 168 KVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQ 227
Query 1055 YRVREDGDSPVFWYAPECL---KEYKFYYASDVWSFGVTLYELL 1095
+P F +APE KEY A D+WS GVT+Y LL
Sbjct 228 LLKSRALGTPAF-FAPELCSTEKEYSCSSAIDIWSLGVTIYCLL 270
Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 47/198 (24%), Positives = 82/198 (41%), Gaps = 41/198 (21%)
Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP-----ENIMVTEYVEHGPL 695
++V+ HH+ + YE +++ T + V C RGP EN M + V GP
Sbjct 105 IEVMKRCHHENVVELYE---ILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAV--GPS 159
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+ ++ R V + S L YL ++ + H ++ N+L++ G +
Sbjct 160 ILTFQQSRK---------VVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGT-------V 203
Query 756 KLSDPGVGLGALSREERVERI-------------PWLAPE-CLPGGANSLSTAMDKWGFG 801
K+SD GV + + ++ + APE C S S+A+D W G
Sbjct 204 KISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLG 263
Query 802 ATLLEICFDGEAPLQSRS 819
T+ + F G+ P + S
Sbjct 264 VTIYCLLF-GKLPFNANS 280
>sp|C0LGD7|Y1684_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g06840 OS=Arabidopsis thaliana OX=3702
GN=At1g06840 PE=1 SV=2
Length=953
Score = 97.1 bits (240), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 87/290 (30%), Positives = 138/290 (48%), Gaps = 39/290 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961
+G+G +GKV Y T G+G +VA+K +A G Q + EI++L L+H +++
Sbjct 631 IGQGGYGKV----YKGT-LGSGTVVAIK--RAQEGSLQGEKEFLTEIELLSRLHHRNLVS 683
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI------CEGMAYLH 1015
G C+++GE+ LV EY+ G+LRD + S+ L + L FA ++ +G+ YLH
Sbjct 684 LLGFCDEEGEQ--MLVYEYMENGTLRDNI---SVKLKEPLDFAMRLRIALGSAKGILYLH 738
Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVP----EGHEYYRVREDGDSPVFWY 1068
+ HRD+ A N+LLD+ K+ DFGL++ P EG V +
Sbjct 739 TEANPPIFHRDIKASNILLDSRFTAKVADFGLSRLAPVPDMEGISPQHVSTVVKGTPGYL 798
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT---KFLELIGIAQGQMTVLRLT 1125
PE ++ SDV+S GV L EL T P T + I IA ++L
Sbjct 799 DPEYFLTHQLTDKSDVYSLGVVLLELFT----GMQPITHGKNIVREINIAYESGSILSTV 854
Query 1126 ELLERGERLPR-PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ +R+ PD+C + L C E RP+ ++ L+ + E
Sbjct 855 D-----KRMSSVPDECLEKFATLALRCCREETDARPSMAEVVRELEIIWE 899
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 73/295 (25%), Positives = 116/295 (39%), Gaps = 50/295 (17%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
+ +GQG VY+G L GSG K E L +G++
Sbjct 629 TQIGQGGYGKVYKGTL---GSGTVVAIKRAQEGSL-----QGEK---------------- 664
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWK 711
F L+S++ H +L + G C E ++V EY+E+G L D + + + A +
Sbjct 665 -EFLTEIELLSRLHHRNLVSLLGFCDEEGEQMLVYEYMENGTLRDNISVKLKEPLDFAMR 723
Query 712 MVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGL 764
+ +A A + YL N + H ++ NILL A+ G S + D G+
Sbjct 724 LRIALGSAKGILYLHTEANPPIFHRDIKASNILLDSRFTAKVADFGLSRLAPVPDME-GI 782
Query 765 GALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS------ 817
V+ P +L PE + L+ D + G LLE+ F G P+
Sbjct 783 SPQHVSTVVKGTPGYLDPEYFL--THQLTDKSDVYSLGVVLLEL-FTGMQPITHGKNIVR 839
Query 818 ------RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
S S +R +P+ + ATL +C E RPS ++R+L
Sbjct 840 EINIAYESGSILSTVDKRMSSVPDECLEKFATLALRCCREETDARPSMAEVVREL 894
>sp|P43637|TOS3_YEAST Serine/threonine-protein kinase TOS3 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=TOS3 PE=1 SV=1
Length=560
Score = 95.9 bits (237), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 70/224 (31%), Positives = 108/224 (48%), Gaps = 40/224 (18%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW-----------KQEIDIL 951
LG G +GKV L + GTG +VA+K L + RSG+ QEI+++
Sbjct 56 LGNGQYGKVKL----ARDLGTGALVAIKILNRF---EKRSGYSLQLKVENPRVNQEIEVM 108
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA----QLLLFAQQ- 1006
+ +HE++++ D + LV+EY G ++ + P + + + +L F Q
Sbjct 109 KRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVK-WCPENKMEIKAVGPSILTFQQSR 167
Query 1007 -----ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG-------HEY 1054
+ G+ YLH+Q HRD+ N+L+ ++ VKI DFG+A + G HE
Sbjct 168 KVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQ 227
Query 1055 YRVREDGDSPVFWYAPECL---KEYKFYYASDVWSFGVTLYELL 1095
+P F +APE KEY A D+WS GVT+Y LL
Sbjct 228 LLKSRALGTPAF-FAPELCSTEKEYSCSSAIDIWSLGVTIYCLL 270
Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 47/198 (24%), Positives = 82/198 (41%), Gaps = 41/198 (21%)
Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP-----ENIMVTEYVEHGPL 695
++V+ HH+ + YE +++ T + V C RGP EN M + V GP
Sbjct 105 IEVMKRCHHENVVELYE---ILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAV--GPS 159
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+ ++ R V + S L YL ++ + H ++ N+L++ G +
Sbjct 160 ILTFQQSRK---------VVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGT-------V 203
Query 756 KLSDPGVGLGALSREERVERI-------------PWLAPE-CLPGGANSLSTAMDKWGFG 801
K+SD GV + + ++ + APE C S S+A+D W G
Sbjct 204 KISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLG 263
Query 802 ATLLEICFDGEAPLQSRS 819
T+ + F G+ P + S
Sbjct 264 VTIYCLLF-GKLPFNANS 280
>sp|Q6NU21|TAO1A_XENLA Serine/threonine-protein kinase TAO1-A
OS=Xenopus laevis OX=8355 GN=taok1-a PE=2 SV=1
Length=1001
Score = 97.1 bits (240), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 78/245 (32%), Positives = 120/245 (49%), Gaps = 32/245 (13%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDI 950
++ +R++G G FG V + +D + T E+VA+K + + G Q W+ +E+
Sbjct 25 EKLFSDLREIGHGSFGAV-YFAHDAS---TREVVAIKKM-SYSGKQSNEKWQDIVKEVKF 79
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQIC 1008
L+ + H + I+YKGC E + LVMEY LGS D L H L ++ + A
Sbjct 80 LQRIKHPNSIEYKGCY--LREHTAWLVMEYC-LGSASDLLEVHKKPLQEIEIAAITHGAL 136
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+G+AYLH+ + IHRD+ A N+LL VK+ DFG A + + +P +W
Sbjct 137 QGLAYLHSHNLIHRDIKAGNILLTEPGQVKLADFGSASIASPANSFV------GTP-YWM 189
Query 1069 APE---CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP----TKFLELIGIAQGQMTV 1121
APE + E ++ DVWS G+T EL + + PP L IAQ +
Sbjct 190 APEVILAMDEGQYDGKVDVWSLGITCIEL-----AERKPPLFNMNAMSALYHIAQNESPT 244
Query 1122 LRLTE 1126
L+ E
Sbjct 245 LQSNE 249
Score = 37.4 bits (85), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 27/88 (31%), Positives = 38/88 (43%), Gaps = 8/88 (9%)
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781
L+YL + NL+H ++ NILL G +KL+D G A V W+AP
Sbjct 139 LAYLHSHNLIHRDIKAGNILLTEPGQ-------VKLADFGSASIASPANSFVGTPYWMAP 191
Query 782 EC-LPGGANSLSTAMDKWGFGATLLEIC 808
E L +D W G T +E+
Sbjct 192 EVILAMDEGQYDGKVDVWSLGITCIELA 219
>sp|Q9LZF8|PCRK2_ARATH Serine/threonine-protein kinase PCRK2 OS=Arabidopsis
thaliana OX=3702 GN=PCRK2 PE=1 SV=1
Length=420
Score = 94.7 bits (234), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 69/203 (34%), Positives = 101/203 (50%), Gaps = 11/203 (5%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG FG V D + ++ VAVK L G Q W E++ L + H +++K
Sbjct 87 IGEGGFGCVFWGTIKNLEDPSKKIEVAVKQL-GKRGLQGHKEWVTEVNFLGVVEHSNLVK 145
Query 962 YKGCCEDQGEKSLQ--LVMEYVPLGSLRDYL-PRHSIGLAQ--LLLFAQQICEGMAYLHA 1016
G C + E+ +Q LV EY+P S+ +L PR L L AQ G+ YLH
Sbjct 146 LLGHCAEDDERGIQRLLVYEYMPNQSVEFHLSPRSPTVLTWDLRLRIAQDAARGLTYLHE 205
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ I RD + N+LLD + K+ DFGLA+ P + V D + + APE +
Sbjct 206 EMDFQIIFRDFKSSNILLDENWTAKLSDFGLARLGPSPGSSH-VSTDVVGTMGYAAPEYI 264
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
+ + SDVW +GV +YEL+T
Sbjct 265 QTGRLTSKSDVWGYGVFIYELIT 287
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 60/266 (23%), Positives = 111/266 (42%), Gaps = 33/266 (12%)
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV----RGPENIMVT 687
D +++ V +K L + + + V H++L + G C RG + ++V
Sbjct 105 DPSKKIEVAVKQLGKRGLQGHKEWVTEVNFLGVVEHSNLVKLLGHCAEDDERGIQRLLVY 164
Query 688 EYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILL 742
EY+ + ++ L R + W ++ +AQ A L+YL + ++ + NILL
Sbjct 165 EYMPNQSVEFHLS-PRSPTVLTWDLRLRIAQDAARGLTYLHEEMDFQIIFRDFKSSNILL 223
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
A+ + + P G +S + V + + APE + G L++ D WG+G
Sbjct 224 DENWTAKLSDFGLARLGPSPGSSHVS-TDVVGTMGYAAPEYIQTG--RLTSKSDVWGYGV 280
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQ---------RQHRL-PEP---------SCPQLAT 843
+ E+ G PL P ++ + R+ RL +P S +LA
Sbjct 281 FIYEL-ITGRRPLDRNKPKGEQKLLEWVRPYLSDTRRFRLIVDPRLEGKYMIKSVQKLAV 339
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + CLT RP +L +T++
Sbjct 340 VANLCLTRNAKARPKMSEVLEMVTKI 365
>sp|P52497|SNF1_CANAX Carbon catabolite-derepressing protein kinase
OS=Candida albicans OX=5476 GN=SNF1 PE=2 SV=2
Length=620
Score = 96.3 bits (238), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 77/219 (35%), Positives = 111/219 (51%), Gaps = 17/219 (8%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQ 939
P PA++P RY + ++ LGEG FGKV L + GTG+ VA+K + K
Sbjct 39 PIDPAANPANRIGRY-QILKTLGEGSFGKVKL----AQHLGTGQKVALKIINRKTLAKSD 93
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLA 998
+ ++EI LR L H HIIK + + E + +V+E+ L DY+ R +
Sbjct 94 MQGRVEREISYLRLLRHPHIIKLYDVIKSKDE--IIMVIEFAG-KELFDYIVQRGKMPED 150
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
+ F QQI + Y H +HRDL N+LLD+ VKI DFGL+ + +G+ ++
Sbjct 151 EARRFFQQIIAAVEYCHRHKIVHRDLKPENLLLDDQLNVKIADFGLSNIMTDGN---FLK 207
Query 1059 EDGDSPVFWYAPECLKEYKFYYA--SDVWSFGVTLYELL 1095
SP + APE + K Y DVWS GV LY +L
Sbjct 208 TSCGSPNYMPAPEVISG-KLYAGPEVDVWSAGVILYVML 245
Score = 34.3 bits (77), Expect = 9.0, Method: Compositional matrix adjust.
Identities = 49/241 (20%), Positives = 89/241 (37%), Gaps = 21/241 (9%)
Query 634 GQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
G +V LK+++ + D+ S + + H H+ ++ V E IMV E+
Sbjct 74 GTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEFA 133
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
D + +RG +P QQ+ +A+ Y +VH ++ N+LL
Sbjct 134 GKELFDYIV--QRGKMPEDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLLL-------D 184
Query 751 TSPFIKLSDPGVGLGALSREERVERIPWLAPECLPG-----GANSLSTAMDKWGFGATLL 805
+K++D GL + + + +P +P G +D W G +L
Sbjct 185 DQLNVKIAD--FGLSNIMTDGNFLKTSCGSPNYMPAPEVISGKLYAGPEVDVWSAG-VIL 241
Query 806 EICFDGEAPLQSR-SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ G P P+ + + LP L ++ L P R + I+
Sbjct 242 YVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSAGAKHLLTRMLVVNPLNRITIHEIME 301
Query 865 D 865
D
Sbjct 302 D 302
>sp|Q3TYD6|LMTK2_MOUSE Serine/threonine-protein kinase LMTK2 OS=Mus
musculus OX=10090 GN=Lmtk2 PE=1 SV=3
Length=1471
Score = 97.1 bits (240), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 86/283 (30%), Positives = 132/283 (47%), Gaps = 49/283 (17%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG-EMVAVKALKADCGPQHRSGWKQEIDILR 952
+ L I+++G G FGKV L T GT V VK LK P+ + + + +
Sbjct 133 RHSLNYIQEIGSGWFGKVLL---GETYTGTSVARVIVKELKVSASPKEQDTFLKSGEPYY 189
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009
L H ++++ G C + LV E+ LG L+ YL H G +Q +L + CE
Sbjct 190 ILQHPNVLQCVGQCVEA--IPYLLVFEFCDLGDLKAYLHNEQEHVRGDSQTMLLQRMACE 247
Query 1010 ---GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED----GD 1062
G+A +H H++H DLA RN L +D VK+GD+G+ + R +ED D
Sbjct 248 IAAGLAAMHKLHFLHSDLALRNCYLTSDLNVKVGDYGIG--------FSRYKEDYIETDD 299
Query 1063 SPVF---WYAPECLKEYKFYYA-------SDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
VF W APE + ++ S++WS GVTL+EL + + P +L
Sbjct 300 KKVFPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVTLWELFNN---AAQPYANLSDLD 356
Query 1113 GIAQGQMTVLRLTELLERGERLPRPD-KCPCEV--YHLMKNCW 1152
+ Q V+R ER +LP+P + P Y +++ CW
Sbjct 357 VLNQ----VIR-----ERDMKLPKPQLEQPYSDRWYEVLQFCW 390
>sp|F4IS56|ILK1_ARATH Integrin-linked protein kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=ILK1 PE=1 SV=1
Length=479
Score = 95.1 bits (235), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 71/259 (27%), Positives = 115/259 (44%), Gaps = 22/259 (8%)
Query 923 TGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
G V+VK L D P+ + ++ E+ +L + H ++I++ G + +V+EY
Sbjct 215 NGTRVSVKILDKDSYSDPERINAFRHELTLLEKVRHPNVIQFVGAVTQN--IPMMIVVEY 272
Query 981 VPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRL 1036
P G L YL + + ++ L FA I GM YLH IH DL +N+LLD
Sbjct 273 NPKGDLSVYLQKKGRLSPSKALRFALDIARGMNYLHECKPDPIIHCDLKPKNILLDRGGQ 332
Query 1037 VKIGDFGLAKAVPEGHEYYRV---REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
+KI FG+ + + +V + D ++ APE K+ F D SFGV LYE
Sbjct 333 LKISGFGMIRLSKISQDKAKVANHKAHIDLSNYYIAPEVYKDEIFDLRVDAHSFGVILYE 392
Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
+ P + + + +G+ V + + P ++ L++ CW
Sbjct 393 ITEGVPVFHPRPPEEVARMMCLEGKRPVFKT-----------KSRSYPPDIKELIEKCWH 441
Query 1154 TEASFRPTFENLIPILKTV 1172
EA RPTF +I L +
Sbjct 442 PEAGIRPTFSEIIIRLDKI 460
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 58/247 (23%), Positives = 102/247 (41%), Gaps = 19/247 (8%)
Query 638 RVVLKVLDPSHH---DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
RV +K+LD + + AF +L+ +V H ++ G + ++V EY G
Sbjct 218 RVSVKILDKDSYSDPERINAFRHELTLLEKVRHPNVIQFVGAVTQNIPMMIVVEYNPKGD 277
Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLG-LAEG 750
L V+L++ +G + + + A +A ++YL ++H ++ +NILL R G L
Sbjct 278 LSVYLQK-KGRLSPSKALRFALDIARGMNYLHECKPDPIIHCDLKPKNILLDRGGQLKIS 336
Query 751 TSPFIKLSDPGVGLGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
I+LS ++ + + ++APE L +D FG L EI
Sbjct 337 GFGMIRLSKISQDKAKVANHKAHIDLSNYYIAPEVYKDEIFDLR--VDAHSFGVILYEIT 394
Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLP------EPSCPQLATLTSQCLTYEPTQRPSFRTI 862
+G R P E + + P P + L +C E RP+F I
Sbjct 395 -EGVPVFHPRPPEEVARMMCLEGKRPVFKTKSRSYPPDIKELIEKCWHPEAGIRPTFSEI 453
Query 863 LRDLTRL 869
+ L ++
Sbjct 454 IIRLDKI 460
>sp|Q5R4F3|TAOK3_PONAB Serine/threonine-protein kinase TAO3 OS=Pongo
abelii OX=9601 GN=TAOK3 PE=2 SV=1
Length=898
Score = 96.7 bits (239), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 73/203 (36%), Positives = 102/203 (50%), Gaps = 23/203 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956
+ ++G G FG V Y TN T E+VA+K + + G Q W+ +E+ LR L H
Sbjct 27 LHEIGHGSFGAV----YFATNAHTNEVVAIKKM-SYSGKQTHEKWQDILKEVKFLRQLKH 81
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014
+ I+YKGC E + LVMEY LGS D L H L ++ + A G+AYL
Sbjct 82 PNTIEYKGCY--LKEHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALHGLAYL 138
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071
H+ IHRD+ A N+LL VK+ DFG A + + +P +W APE
Sbjct 139 HSHALIHRDIKAGNILLTEPGQVKLADFGSASVASPANSFV------GTP-YWMAPEVIL 191
Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094
+ E ++ DVWS G+T EL
Sbjct 192 AMDEGQYDGKVDVWSLGITCIEL 214
Score = 36.6 bits (83), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 47/204 (23%), Positives = 72/204 (35%), Gaps = 22/204 (11%)
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781
L+YL + L+H ++ NILL G +KL+D G A V W+AP
Sbjct 135 LAYLHSHALIHRDIKAGNILLTEPGQ-------VKLADFGSASVASPANSFVGTPYWMAP 187
Query 782 EC-LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--C 838
E L +D W G T +E+ A + S H Q + +
Sbjct 188 EVILAMDEGQYDGKVDVWSLGITCIELAERKPALFNMNAMSALYHIAQNDSPTLQSNEWT 247
Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898
CL P +RP+ +LR H+ V D P +R
Sbjct 248 DSFRRFVDYCLQKIPQERPTSAELLR-------HDF-----VRRDRPLRVLIDLIQRTKD 295
Query 899 KIRDLGEGHFGKVSLYCYDPTNDG 922
+R+L + K+ + T +G
Sbjct 296 AVRELDNLQYRKMKKILFQETRNG 319
>sp|Q9M0T3|MP3K3_ARATH Mitogen-activated protein kinase kinase
kinase 3 OS=Arabidopsis thaliana OX=3702 GN=MEKK3 PE=2 SV=1
Length=560
Score = 95.9 bits (237), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 72/271 (27%), Positives = 122/271 (45%), Gaps = 34/271 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQ---EIDILRTLYHEH 958
LG G + V Y+ ++ G+ AVK + D G Q + +Q EI +L L H++
Sbjct 309 LGRGSYASV----YEAISED-GDFFAVKEVSLLDKGIQAQECIQQLEGEIALLSQLQHQN 363
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I++Y+G +D + L + +E V GS++ R+ + + L+ +QI G+ YLH +
Sbjct 364 IVRYRGTAKDVSK--LYIFLELVTQGSVQKLYERYQLSYTVVSLYTRQILAGLNYLHDKG 421
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
++HRD+ N+L+D + VK+ DFGLA+A + +FW APE +
Sbjct 422 FVHRDIKCANMLVDANGTVKLADFGLAEA-----SKFNDIMSCKGTLFWMAPEVINRKDS 476
Query 1079 Y---YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+D+WS G T+ E+ T I + ++ + RG
Sbjct 477 DGNGSPADIWSLGCTVLEMCTG---------------QIPYSDLKPIQAAFKIGRGTLPD 521
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
PD + H + C + RPT L+
Sbjct 522 VPDTLSLDARHFILTCLKVNPEERPTAAELL 552
Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 53/214 (25%), Positives = 92/214 (43%), Gaps = 25/214 (12%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
+L+SQ+ H ++ G + + E V G V ER + + +Q+
Sbjct 354 ALLSQLQHQNIVRYRGTAKDVSKLYIFLELVTQG--SVQKLYERYQLSYTVVSLYTRQIL 411
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER---- 775
+ L+YL +K VH ++ N+L+ A GT +KL+D GL S+ +
Sbjct 412 AGLNYLHDKGFVHRDIKCANMLVD----ANGT---VKLAD--FGLAEASKFNDIMSCKGT 462
Query 776 IPWLAPECLP-GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834
+ W+APE + ++ + D W G T+LE+C G+ P P + + R
Sbjct 463 LFWMAPEVINRKDSDGNGSPADIWSLGCTVLEMC-TGQIPYSDLKPIQAAF---KIGRGT 518
Query 835 EPSCPQLATLTSQ-----CLTYEPTQRPSFRTIL 863
P P +L ++ CL P +RP+ +L
Sbjct 519 LPDVPDTLSLDARHFILTCLKVNPEERPTAAELL 552
>sp|Q54DF2|MRKA_DICDI Probable serine/threonine-protein kinase
MARK-A OS=Dictyostelium discoideum OX=44689 GN=mrkA PE=3 SV=1
Length=1060
Score = 97.1 bits (240), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 67/201 (33%), Positives = 105/201 (52%), Gaps = 14/201 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEH 958
I+ +G G FGKV L + E VA+K + K P+ ++E+ I++ L+H +
Sbjct 112 IKTIGRGQFGKVKLGYHKKI---PNEKVAIKIINKGKLDPETLKMVQREVRIMKLLHHPN 168
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQ 1017
II+ E ++L L+MEY G + D++ H + +Q F QI + Y H++
Sbjct 169 IIRLYEVIE--TSRALYLIMEYAGEGEVMDFMIAHGVLTESQARTFFTQIVSAINYCHSK 226
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL--KE 1075
+HRDL N+LLD +R +KI DFGL+ G ++ SP + +PE + KE
Sbjct 227 RAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGS---YLKTFCGSPTYA-SPELILRKE 282
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
Y + DVWS GV L+ L+T
Sbjct 283 YNG-PSVDVWSMGVVLFVLVT 302
>sp|P08458|SPS1_YEAST Sporulation-specific protein 1 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SPS1
PE=1 SV=2
Length=490
Score = 95.1 bits (235), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 67/200 (34%), Positives = 102/200 (51%), Gaps = 19/200 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G+FG V Y + T E+VA+K + + + QEI L L I Y
Sbjct 24 IGRGNFGDV----YKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNY 79
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GL--AQLLLFAQQICEGMAYLHAQHY 1019
+ + S+ +VMEY GS D L R + GL ++ ++ G+ YLH Q
Sbjct 80 IATMLE--DVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRK 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVFWYAPE--CLKE 1075
IHRD+ A N+LL+ + +VK+GDFG++ GH ++ D +P +W APE C +
Sbjct 138 IHRDIKAANILLNEEGMVKLGDFGVS-----GHIRSTLKRDTFVGTP-YWMAPEVVCCEV 191
Query 1076 YKFYYASDVWSFGVTLYELL 1095
+ +D+WS G+T YELL
Sbjct 192 DGYNEKADIWSLGITTYELL 211
Score = 51.2 bits (121), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 58/243 (24%), Positives = 93/243 (38%), Gaps = 23/243 (9%)
Query 632 DRGQELRVVLKVLDPSHHD-----IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
DR + V +KV++ H D +A + A L S + ++A + +V
Sbjct 37 DRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIA----TMLEDVSMWIV 92
Query 687 TEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
EY G L+R + +P + ++ L YL + +H ++ NILL
Sbjct 93 MEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEE 152
Query 746 GLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
G+ +KL D GV L R+ V W+APE + + + D W G
Sbjct 153 GM-------VKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGI 205
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
T E+ G PL P + ++ +L P + CL P RPS
Sbjct 206 TTYEL-LKGLPPLSKYDPMKVMTNLPKRKPPKLQGPFSDAAKDFVAGCLVKTPADRPSAY 264
Query 861 TIL 863
+L
Sbjct 265 NLL 267
>sp|P43298|TMK1_ARATH Receptor protein kinase TMK1 OS=Arabidopsis
thaliana OX=3702 GN=TMK1 PE=1 SV=1
Length=942
Score = 96.7 bits (239), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 78/222 (35%), Positives = 107/222 (48%), Gaps = 22/222 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
LG G FG V +DGT +AVK ++ + + +K EI +L + H H++
Sbjct 594 LGSGGFGVV---YKGELHDGT--KIAVKRMENGVIAGKGFAEFKSEIAVLTKVRHRHLVT 648
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYLH 1015
G C D EK LV EY+P G+L +L S + Q L A + G+ YLH
Sbjct 649 LLGYCLDGNEK--LLVYEYMPQGTLSRHLFEWSEEGLKPLLWKQRLTLALDVARGVEYLH 706
Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APE 1071
Q +IHRDL N+LL +D K+ DFGL + PEG R G F Y APE
Sbjct 707 GLAHQSFIHRDLKPSNILLGDDMRAKVADFGLVRLAPEGKGSIETRIAG---TFGYLAPE 763
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELI 1112
+ DV+SFGV L EL+T S +S P + + L+
Sbjct 764 YAVTGRVTTKVDVYSFGVILMELITGRKSLDESQPEESIHLV 805
Score = 62.4 bits (150), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 65/247 (26%), Positives = 109/247 (44%), Gaps = 41/247 (17%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD--VWLRRERGHVPMAWK- 711
F +++++V H HL + G C+ G E ++V EY+ G L ++ E G P+ WK
Sbjct 631 FKSEIAVLTKVRHRHLVTLLGYCLDGNEKLLVYEYMPQGTLSRHLFEWSEEGLKPLLWKQ 690
Query 712 -MVVAQQLASALSY---LENKNLVHGNVCGRNILLA---RLGLAEGTSPFIKLSDPGVGL 764
+ +A +A + Y L +++ +H ++ NILL R +A+ ++L+ G G
Sbjct 691 RLTLALDVARGVEYLHGLAHQSFIHRDLKPSNILLGDDMRAKVAD--FGLVRLAPEGKG- 747
Query 765 GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
S E R+ +LAPE G ++T +D + FG L+E+ G L P E
Sbjct 748 ---SIETRIAGTFGYLAPEYAVTG--RVTTKVDVYSFGVILMEL-ITGRKSLDESQPEES 801
Query 824 EH---FYQRQHRLPEPSCPQ------------------LATLTSQCLTYEPTQRPSFRTI 862
H +++R + E S + +A L C EP QRP
Sbjct 802 IHLVSWFKRMYINKEASFKKAIDTTIDLDEETLASVHTVAELAGHCCAREPYQRPDMGHA 861
Query 863 LRDLTRL 869
+ L+ L
Sbjct 862 VNILSSL 868
>sp|Q0IHQ8|STK10_XENTR Serine/threonine-protein kinase 10 OS=Xenopus
tropicalis OX=8364 GN=stk10 PE=2 SV=1
Length=951
Score = 96.7 bits (239), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 85/287 (30%), Positives = 134/287 (47%), Gaps = 42/287 (15%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I +LG+G FGKV Y N TG + A K ++ + + EI+IL T H I
Sbjct 39 IGELGDGAFGKV----YKAKNKETGILAAAKVIETK-NEEELEDYMVEIEILATCNHHFI 93
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQ 1017
+K G +G+ L +++E+ P G++ + GL + + +Q+ EG+ YLH+
Sbjct 94 VKLLGSYYWEGK--LWIMIEFCPGGAVDAIMLELDRGLKEPEIRTICRQMLEGLTYLHSM 151
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVFWYAP-----E 1071
IHRDL A NVLL D +K+ DFG+ AK V + + R+ +W AP E
Sbjct 152 KMIHRDLKAGNVLLTLDGDIKLADFGVSAKNV----KTLQRRDSFIGTPYWMAPEVVMCE 207
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE----LIGIAQGQMTVLRLTEL 1127
+K+ + Y +D+WS G+TL E+ + PP L L+ IA+ +
Sbjct 208 TMKDAPYDYKADIWSLGITLIEM-----AQIEPPHHELNPMRVLLKIAKSEPPT------ 256
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTV 1172
L P K E ++ +K + RP+ L+ P +K V
Sbjct 257 ------LSSPSKWSPEFHNFLKTALDKNPETRPSAAQLLEHPFVKKV 297
Score = 39.3 bits (90), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 29/103 (28%), Positives = 45/103 (44%), Gaps = 14/103 (14%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV---GLGALSR 769
+ +Q+ L+YL + ++H ++ N+LL G IKL+D GV + L R
Sbjct 136 TICRQMLEGLTYLHSMKMIHRDLKAGNVLLTLDG-------DIKLADFGVSAKNVKTLQR 188
Query 770 EERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808
+ P W+APE C D W G TL+E+
Sbjct 189 RDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIEMA 231
>sp|Q8R4K2|IRAK4_MOUSE Interleukin-1 receptor-associated kinase
4 OS=Mus musculus OX=10090 GN=Irak4 PE=1 SV=1
Length=459
Score = 94.7 bits (234), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 71/202 (35%), Positives = 100/202 (50%), Gaps = 19/202 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC---GPQHRSGWKQEIDILRTLYHEHI 959
+GEG FG V C + T +VAVK L A + + + QEI ++ T HE++
Sbjct 192 MGEGGFGVVYKGCVNNT------IVAVKKLGAMVEISTEELKQQFDQEIKVMATCQHENL 245
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLH 1015
++ G D +L LV Y+P GSL D L + AQ G+ +LH
Sbjct 246 VELLGFSSDS--DNLCLVYAYMPNGSLLDRLSCLDGTPPLSWHTRCKVAQGTANGIRFLH 303
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLK 1074
H+IHRD+ + N+LLD D KI DFGLA+A R G + + APE L+
Sbjct 304 ENHHIHRDIKSANILLDKDFTAKISDFGLARASARLAQTVMTSRIVGTTA--YMAPEALR 361
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ SD++SFGV L EL+T
Sbjct 362 G-EITPKSDIYSFGVVLLELIT 382
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 53/243 (22%), Positives = 100/243 (41%), Gaps = 33/243 (14%)
Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+++ S ++ F + +M+ H +L + G +V Y+ +G L L
Sbjct 218 MVEISTEELKQQFDQEIKVMATCQHENLVELLGFSSDSDNLCLVYAYMPNGSLLDRLSCL 277
Query 703 RGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G P++W + VAQ A+ + +L + +H ++ NILL + A K+SD
Sbjct 278 DGTPPLSWHTRCKVAQGTANGIRFLHENHHIHRDIKSANILLDKDFTA-------KISDF 330
Query 761 GVGLGA--LSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ + L++ RI ++APE L G ++ D + FG LLE+ A
Sbjct 331 GLARASARLAQTVMTSRIVGTTAYMAPEALRG---EITPKSDIYSFGVVLLELITGLAAV 387
Query 815 LQSRSPS---------------EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859
++R P +++ ++ S + + SQCL + +RP
Sbjct 388 DENREPQLLLDIKEEIEDEEKTIEDYTDEKMSDADPASVEAMYSAASQCLHEKKNRRPDI 447
Query 860 RTI 862
+
Sbjct 448 AKV 450
>sp|H2KZW3|M3K20_CAEEL Mitogen-activated protein kinase kinase
kinase zak-1 OS=Caenorhabditis elegans OX=6239 GN=zak-1 PE=2
SV=1
Length=745
Score = 96.3 bits (238), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 80/277 (29%), Positives = 123/277 (44%), Gaps = 43/277 (16%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + DG+ +A+K + ++E +IL + H++II++
Sbjct 37 IGVGTFGAVFSGNW-TLPDGSQRTIALKKVFV---------LEKEAEILSKIRHKNIIQF 86
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQ---------LLLFAQQICEGMA 1012
G C+ G +V EY GSL D++ S A ++ +A QI G+
Sbjct 87 YGICKATGNDFF-IVTEYAEKGSLYDFIHSEESQSFASSSGGNSFDVVVKWASQIASGIQ 145
Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH IHRDL ++NV+LD + + KI DFG +K + H G + W +
Sbjct 146 YLHYDAVDTIIHRDLKSKNVVLDKNLVCKICDFGTSKDLT--HSCTAPSWGGTAA--WMS 201
Query 1070 PE-CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE L+ A+DVWS+GV L+E+L S + P + E T +
Sbjct 202 PEMILQSEGLTTATDVWSYGVVLWEIL----SKEVPYKDYSEF----------RIFTMIT 247
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ G L P CP + LM NCW+ R +
Sbjct 248 QSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQI 284
>sp|Q8GX23|PERK5_ARATH Proline-rich receptor-like protein kinase
PERK5 OS=Arabidopsis thaliana OX=3702 GN=PERK5 PE=2 SV=1
Length=670
Score = 95.9 bits (237), Expect = 8e-19, Method: Compositional matrix adjust.
Identities = 73/203 (36%), Positives = 101/203 (50%), Gaps = 22/203 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V +G+ VAVK+LK G R ++ E+DI+ ++H H++
Sbjct 318 LGQGGFGYVHKGVLP-----SGKEVAVKSLKLGSGQGERE-FQAEVDIISRVHHRHLVSL 371
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017
G C G++ LV E++P +L +L H G L + A G+AYLH
Sbjct 372 VGYCISGGQR--LLVYEFIPNNTLEFHL--HGKGRPVLDWPTRVKIALGSARGLAYLHED 427
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECL 1073
IHRD+ A N+LLD K+ DFGLAK + + + R G F Y APE
Sbjct 428 CHPRIIHRDIKAANILLDFSFETKVADFGLAKLSQDNYTHVSTRVMG---TFGYLAPEYA 484
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
K SDV+SFGV L EL+T
Sbjct 485 SSGKLSDKSDVFSFGVMLLELIT 507
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 50/173 (29%), Positives = 76/173 (44%), Gaps = 25/173 (14%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F ++S+V H HL + G C+ G + ++V E++ + L+ L +G + W V
Sbjct 353 FQAEVDIISRVHHRHLVSLVGYCISGGQRLLVYEFIPNNTLEFHLHG-KGRPVLDWPTRV 411
Query 715 AQQLASA--LSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
L SA L+YL ++H ++ NILL S K++D GL LS+
Sbjct 412 KIALGSARGLAYLHEDCHPRIIHRDIKAANILLD-------FSFETKVAD--FGLAKLSQ 462
Query 770 EERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
+ +LAPE G LS D + FG LLE+ G PL
Sbjct 463 DNYTHVSTRVMGTFGYLAPEYASSG--KLSDKSDVFSFGVMLLEL-ITGRPPL 512
>sp|P53666|LIMK2_CHICK LIM domain kinase 2 OS=Gallus gallus OX=9031
GN=LIMK2 PE=2 SV=1
Length=642
Score = 95.9 bits (237), Expect = 8e-19, Method: Compositional matrix adjust.
Identities = 63/211 (30%), Positives = 105/211 (50%), Gaps = 25/211 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+ T+ TG+++ +K L C + + + E+ ++R+L H +++K+
Sbjct 337 LGKGFFGQA----IKVTHKATGKVMVMKEL-IRCDEETQKTFLTEVKVMRSLDHPNVLKF 391
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G +K L L+ EY+ G+L+D+L Q + FA+ I GMAYLH+ IH
Sbjct 392 IGVL--YKDKKLNLLTEYIEGGTLKDFLRNADPFPWQQKVSFAKGIASGMAYLHSMCIIH 449
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE---------YYRVREDGDSPV------- 1065
RDL + N L+ D+ V + DFGL++ + E + R D
Sbjct 450 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKKPTLEKPSAKKRTLRKSDRKKRYTVVGN 509
Query 1066 -FWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+W APE L + D++SFG+ L E++
Sbjct 510 PYWMAPEMLNGQSYDETVDIFSFGIVLCEII 540
Score = 57.8 bits (138), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 62/250 (25%), Positives = 100/250 (40%), Gaps = 35/250 (14%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+V+K L + F +M + H ++ GV + + ++TEY+E G L +
Sbjct 357 MVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDF 416
Query 699 LRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNIL-------------LA 743
LR P W K+ A+ +AS ++YL + ++H ++ N L L+
Sbjct 417 LRNAD---PFPWQQKVSFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLS 473
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAMDK 797
RL + E P L P L + +R +R W+APE L G S +D
Sbjct 474 RLIVEERKKP--TLEKPSAKKRTLRKSDRKKRYTVVGNPYWMAPEMLNG--QSYDETVDI 529
Query 798 WGFGATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYE 852
+ FG L EI A P + F+++ +P P L + C E
Sbjct 530 FSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEK--FVPADCPPAFFPLAAICCRLE 587
Query 853 PTQRPSFRTI 862
P RP F +
Sbjct 588 PESRPPFSKL 597
>sp|P53668|LIMK1_MOUSE LIM domain kinase 1 OS=Mus musculus OX=10090
GN=Limk1 PE=1 SV=1
Length=647
Score = 95.9 bits (237), Expect = 8e-19, Method: Compositional matrix adjust.
Identities = 79/296 (27%), Positives = 133/296 (45%), Gaps = 41/296 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+ T+ TGE++ +K L R+ K E+ ++R L H +++K+
Sbjct 345 LGKGCFGQA----IKVTHRETGEVMVMKELIRFDEETQRTFLK-EVKVMRCLEHPNVLKF 399
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYI 1020
G +K L + EY+ G+LR + +Q + FA+ I GMAYLH+ + I
Sbjct 400 IGVL--YKDKRLNFITEYIKGGTLRGIIKNMDSQYPWSQRVSFAKDIASGMAYLHSMNII 457
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAV---------------PEGHEYYRVREDGDSPV 1065
HRDL + N L+ +R V + DFGLA+ + P+ + Y V +
Sbjct 458 HRDLNSHNCLVRENRNVVVADFGLARLMIDEKNQSEDLRSLKKPDRKKRYTVVGNP---- 513
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+W APE + + DV+SFG+ L E++ ++ + ++ L +
Sbjct 514 YWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDF---------GLNVR 564
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
L+R P CP + + C + + RP+F L L+T+ G P
Sbjct 565 GFLDRY----CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETLRMHLSGHLP 616
Score = 66.2 bits (160), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 60/251 (24%), Positives = 110/251 (44%), Gaps = 22/251 (9%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+V+K L + F + +M + H ++ GV + +TEY++ G L
Sbjct 365 MVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGI 424
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNV----C----GRNILLARLGLAEG 750
++ P + ++ A+ +AS ++YL + N++H ++ C RN+++A GLA
Sbjct 425 IKNMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLAR- 483
Query 751 TSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAMDKWGFGATL 804
I + L +L + +R +R W+APE + G S +D + FG L
Sbjct 484 --LMIDEKNQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMING--RSYDEKVDVFSFGIVL 539
Query 805 LEIC--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSC-PQLATLTSQCLTYEPTQRPSFRT 861
EI + + R+ + R P+C P +T +C +P +RPSF
Sbjct 540 CEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVK 599
Query 862 ILRDLTRLQPH 872
+ + L L+ H
Sbjct 600 LEQWLETLRMH 610
>sp|A4K2M3|STK4_PAPAN Serine/threonine-protein kinase 4 OS=Papio
anubis OX=9555 GN=STK4 PE=3 SV=1
Length=487
Score = 94.7 bits (234), Expect = 9e-19, Method: Compositional matrix adjust.
Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V Y + TG++VA+K + + Q +EI I++ H+
Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 144 RKIHRDIKAGNILLNTEGQAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 201 YNCVADIWSLGITAIEM 217
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/228 (24%), Positives = 84/228 (37%), Gaps = 21/228 (9%)
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
P D+ E S+M Q H+ +G + + +V EY G + +R
Sbjct 62 PVESDLQEIIKEI-SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKT 120
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763
+ + Q L YL +H ++ NILL G A KL+D GV
Sbjct 121 LTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGQA-------KLADFGVAGQ 173
Query 764 -LGALSREERVERIP-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+++ V P W+APE + G N ++ D W G T +E+ +G+ P P
Sbjct 174 LTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHP 229
Query 821 SEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R PE QCL P QR + +L+
Sbjct 230 MRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQ 277
>sp|Q54R58|YTYK2_DICDI Probable tyrosine-protein kinase DDB_G0283397
OS=Dictyostelium discoideum OX=44689 GN=DDB_G0283397
PE=3 SV=1
Length=918
Score = 95.9 bits (237), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 87/290 (30%), Positives = 127/290 (44%), Gaps = 37/290 (13%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK--ALKADCGPQHRSGWKQEIDILR 952
R L +++G+G FGKV + G+ VA+K L + +E+ I+
Sbjct 175 RELTVEKEIGQGFFGKVYKARW------RGKSVALKKITLIKFRDLTETEIFDKEVSIMS 228
Query 953 TLYHEHIIKYKGCCEDQG-EKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQIC 1008
L H + + G C G ++MEY+ GSLR L S + + L A+ I
Sbjct 229 KLCHPTCVMFIGACSLDGPSNDRSIIMEYMEGGSLRRLLDEKSSYHLPPSLQLSIARDIA 288
Query 1009 EGMAYLHAQH----YIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDS 1063
EGM YLH +HRDL + N+LL++ V KI DFGL+K + G
Sbjct 289 EGMNYLHTNFKEGPIVHRDLTSSNILLNSSYTVAKINDFGLSKEMKPGPTEMTA---AMG 345
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
+ W APEC K + DV+SF + L+E++T D M LR
Sbjct 346 SLAWMAPECFKAENYTEKVDVYSFAIILWEIVTCRD---------------PYNGMEPLR 390
Query 1124 LTELLERGE-RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
L L + RLP P V L+ CW S RP+F+ ++ IL +
Sbjct 391 LAFLASVEDYRLPLNGFPPYWV-ELISKCWNITPSLRPSFKEILQILNQI 439
Score = 77.8 bits (190), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 78/312 (25%), Positives = 135/312 (43%), Gaps = 54/312 (17%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S L H + +E+T +GQG VY+ R R G+ +
Sbjct 165 STLKKHEIPSRELTVEKEIGQGFFGKVYKARWR--------------------GKSVALK 204
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSH-THLAFVHGVCVRGPEN--IMVTEYVEHG 693
++K D + +I F + S+MS++ H T + F+ + GP N ++ EY+E G
Sbjct 205 KITLIKFRDLTETEI---FDKEVSIMSKLCHPTCVMFIGACSLDGPSNDRSIIMEYMEGG 261
Query 694 PLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKN----LVHGNVCGRNILLARLGLA 748
L L + H+P + ++ +A+ +A ++YL +VH ++ NILL
Sbjct 262 SLRRLLDEKSSYHLPPSLQLSIARDIAEGMNYLHTNFKEGPIVHRDLTSSNILL------ 315
Query 749 EGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+ K++D G+ G + + W+APEC A + + +D + F L
Sbjct 316 NSSYTVAKINDFGLSKEMKPGPTEMTAAMGSLAWMAPECFK--AENYTEKVDVYSFAIIL 373
Query 805 LEIC-----FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQRPS 858
EI ++G PL+ + E + RLP P L S+C P+ RPS
Sbjct 374 WEIVTCRDPYNGMEPLRLAFLASVEDY-----RLPLNGFPPYWVELISKCWNITPSLRPS 428
Query 859 FRTILRDLTRLQ 870
F+ IL+ L +++
Sbjct 429 FKEILQILNQIE 440
>sp|Q9LRY1|PBL25_ARATH Probable serine/threonine-protein kinase
PBL25 OS=Arabidopsis thaliana OX=3702 GN=PBL25 PE=2 SV=1
Length=381
Score = 93.2 bits (230), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 96/319 (30%), Positives = 151/319 (47%), Gaps = 37/319 (12%)
Query 875 ADVLTVNPDSPASD--PTVFHKRYL----KKIRD---LGEGHFGKVSLYCYDPTNDGTGE 925
+V+ N + P+++ +F R L K R +GEG FG+V Y + +
Sbjct 34 GEVVAKNANGPSNNMGARIFTFRELATATKNFRQECLIGEGGFGRV----YKGKLENPAQ 89
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
+VAVK L + G Q + + E+ +L L+H +++ G C D G++ L LV EY+PLGS
Sbjct 90 VVAVKQLDRN-GLQGQREFLVEVLMLSLLHHRNLVNLIGYCAD-GDQRL-LVYEYMPLGS 146
Query 986 LRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLV 1037
L D+L G L + A +G+ YLH + I+RDL + N+LLD + +
Sbjct 147 LEDHLLDLEPGQKPLDWNTRIKIALGAAKGIEYLHDEADPPVIYRDLKSSNILLDPEYVA 206
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
K+ DFGLAK P G + V + APE + SDV+SFGV L EL++
Sbjct 207 KLSDFGLAKLGPVGDTLH-VSSRVMGTYGYCAPEYQRTGYLTNKSDVYSFGVVLLELISG 265
Query 1098 ---CDSSQSPPTKFLELIG----IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
D+ + P+ L+ I + +L + L RG+ P+K + +
Sbjct 266 RRVIDTMR--PSHEQNLVTWALPIFRDPTRYWQLADPLLRGD---YPEKSLNQAIAVAAM 320
Query 1151 CWETEASFRPTFENLIPIL 1169
C E + RP ++I L
Sbjct 321 CLHEEPTVRPLMSDVITAL 339
Score = 55.8 bits (133), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 81/346 (23%), Positives = 136/346 (39%), Gaps = 63/346 (18%)
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEG 612
P T+ ++ + A + +F + K Q +G+G VY+G+L
Sbjct 29 PKRTTGEVVAKNANGPSNNMGARIFTFRELATATKNFRQECLIGEGGFGRVYKGKL---- 84
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672
E+P V +K LD + F ++S + H +L
Sbjct 85 -----------ENP---------AQVVAVKQLDRNGLQGQREFLVEVLMLSLLHHRNLVN 124
Query 673 VHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN 729
+ G C G + ++V EY+ G L D L E G P+ W ++ +A A + YL ++
Sbjct 125 LIGYCADGDQRLLVYEYMPLGSLEDHLLDLEPGQKPLDWNTRIKIALGAAKGIEYLHDEA 184
Query 730 ---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERV-ERIPWLAPECL 784
+++ ++ NILL +A KLSD G+ LG + V R+ C
Sbjct 185 DPPVIYRDLKSSNILLDPEYVA-------KLSDFGLAKLGPVGDTLHVSSRVMGTYGYCA 237
Query 785 PGGANS--LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH--------------FYQ 828
P + L+ D + FG LLE+ G + + PS +++ ++Q
Sbjct 238 PEYQRTGYLTNKSDVYSFGVVLLEL-ISGRRVIDTMRPSHEQNLVTWALPIFRDPTRYWQ 296
Query 829 RQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
L PE S Q + + CL EPT RP ++ L+ L
Sbjct 297 LADPLLRGDYPEKSLNQAIAVAAMCLHEEPTVRPLMSDVITALSFL 342
>sp|G4NEB8|MST7_PYRO7 Mitogen-activated protein kinase kinae MST7
OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC
8958) OX=242507 GN=MST7 PE=1 SV=1
Length=415
Score = 93.6 bits (231), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 77/281 (27%), Positives = 133/281 (47%), Gaps = 34/281 (12%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ I+DLG G+ G VS + PTN ++A K + + + R +E+ I+ +
Sbjct 61 LEVIKDLGSGNGGTVSKVRHIPTN----TVMARKVIHVEAKREMRKRIVRELQIMHSCNS 116
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYL 1014
E+I+ + G ++ + + MEY +GSL D + R I + L A+ G+ YL
Sbjct 117 EYIVTFYGAFLNENNDVI-MCMEYADVGSL-DRVSRVFGPIRVDVLGKIAEATLGGLTYL 174
Query 1015 HAQHYI-HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+A+H+I HRD+ N+L+++ +K+ DFG++ G + + + APE +
Sbjct 175 YAKHHIMHRDIKPSNILVNSRGSIKLCDFGVS-----GELINSIADTFVGTSTYMAPERI 229
Query 1074 KEYKFYYASDVWSFGVTLYELLT---------HCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+ K+ SDVWSFG+++ EL ++S P L+L+ Q V
Sbjct 230 QGEKYTVKSDVWSFGLSIMELAIGKFPFAASEQLSDAESAPAGILDLL-----QQIV--- 281
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
E +LP+ D P + +++ C RPT E L
Sbjct 282 ---HEPAPKLPKSDAFPQILEDMIQKCLYKNPDDRPTPEEL 319
>sp|A4K2W5|STK4_AOTNA Serine/threonine-protein kinase 4 OS=Aotus
nancymaae OX=37293 GN=STK4 PE=3 SV=1
Length=487
Score = 94.4 bits (233), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V Y + TG++VA+K + + Q +EI I++ H+
Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSHHV 85
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 201 YNCVADIWSLGITAIEM 217
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q H+ +G + + +V EY G + +R + + Q
Sbjct 75 SIMQQCDSHHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL +H ++ NILL G A KL+D GV +++ V
Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187
Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830
P W+APE + G N ++ D W G T +E+ +G+ P P
Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R PE QCL P QR + +L+
Sbjct 244 FRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQ 277
>sp|Q86I06|NEK3_DICDI Probable serine/threonine-protein kinase
nek3 OS=Dictyostelium discoideum OX=44689 GN=nek3 PE=3 SV=1
Length=1123
Score = 96.3 bits (238), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 71/285 (25%), Positives = 133/285 (47%), Gaps = 50/285 (18%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEH 958
I+ +G+G FG+ L G ++ +K + + P+ RS E+++L L HE+
Sbjct 7 IKTIGKGSFGRAILV----KRKSDGLLLVLKEINVMEMQPKERSDAMNEVNLLSMLDHEN 62
Query 959 IIKY------KGCCEDQGEKSLQLVMEYVPLGSL-----RDYLPRHSIGLAQLLLFAQQI 1007
II Y GC L ++MEY G + + L + ++L + QI
Sbjct 63 IIGYYDSFILNGC--------LYIIMEYANAGDINLEIKKRTLQNKTFSEFEILSWFSQI 114
Query 1008 CEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
C+ + Y+ +++ +HRDL +N+ L + D +K+GDFG+AK + E +P
Sbjct 115 CKALQYISSRNILHRDLKTQNIFLSIVNGDYFIKLGDFGIAKIL--NSETSLASTVLGTP 172
Query 1065 VFWYAPECLKEYKFY-YASDVWSFGVTLYELLT--HCDSSQSPPTKFLELIGIAQGQMTV 1121
++ +PE ++ K Y + SD+WS G LYEL T H ++ + P L+++
Sbjct 173 -YYLSPELIQNEKGYDHKSDIWSLGCVLYELTTLKHAFNAANLPALVLKIL--------- 222
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+G P P ++ +L+ + + + RP+ +++
Sbjct 223 --------KGTYPPIPSHYSNDLRNLISSMLQIDPKNRPSVNDIL 259
Score = 37.7 bits (86), Expect = 0.85, Method: Compositional matrix adjust.
Identities = 47/219 (21%), Positives = 89/219 (41%), Gaps = 25/219 (11%)
Query 659 ASLMSQVSHTHL-----AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
+L+S + H ++ +F+ C+ ++ EY G +++ +++ +
Sbjct 52 VNLLSMLDHENIIGYYDSFILNGCLY-----IIMEYANAGDINLEIKKRTLQNKTFSEFE 106
Query 714 VAQ---QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ Q+ AL Y+ ++N++H ++ +NI L+ + G FIKL D G+ L+ E
Sbjct 107 ILSWFSQICKALQYISSRNILHRDLKTQNIFLS---IVNGDY-FIKLGDFGIA-KILNSE 161
Query 771 ERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
+ +L+PE + D W G L E+ A + P+
Sbjct 162 TSLASTVLGTPYYLSPELI-QNEKGYDHKSDIWSLGCVLYELTTLKHAFNAANLPALVLK 220
Query 826 FYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
+ + +P L L S L +P RPS IL
Sbjct 221 ILKGTYPPIPSHYSNDLRNLISSMLQIDPKNRPSVNDIL 259
>sp|A0A2R6XIK6|PRAF_MARPO RAF-like serine/threonine-protein kinase
PRAF OS=Marchantia polymorpha OX=3197 GN=PRAF PE=1 SV=1
Length=1680
Score = 96.3 bits (238), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 88/297 (30%), Positives = 135/297 (45%), Gaps = 41/297 (14%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-----GPQHR---SGWKQEI 948
L+++R+LG G FG V + T+ VA+K +KA C Q R W++
Sbjct 1389 LEELRELGSGTFGTVYHGKWRGTD------VAIKRIKASCFAGRPSEQERLIEDFWREAC 1442
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQ 1006
+ L L+H +++ + G D +L V EY+ GSL+ L + +I + LL A
Sbjct 1443 N-LGHLHHPNVVAFYGVVADGPGGTLATVTEYMVNGSLKQVLQKKDRTIDRRKRLLIAMD 1501
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLD----NDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
GM YLH ++ +H DL N+L++ + + K+GD GL+K + VR G
Sbjct 1502 AAFGMEYLHGKNIVHFDLKCENLLVNMRDPHRPICKVGDLGLSKVKHQTMVSGGVR--GT 1559
Query 1063 SPVFWYAPECLKEYKFYYAS--DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
P W APE L DV+SFG+ ++ELLT + P K G G +
Sbjct 1560 LP--WMAPELLNGNSSLVTEKVDVFSFGIVMWELLT----GEEPYDKM--HYGAIIGGIV 1611
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
L L+ P C LM+ CW E + RP+F ++ L+T+ Q
Sbjct 1612 NNTLRPLI--------PSWCDPAWRSLMERCWANEPAVRPSFSDIAKELRTMAAALQ 1660
Score = 75.1 bits (183), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 74/317 (23%), Positives = 131/317 (41%), Gaps = 54/317 (17%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG-QELRV 639
+ ++ +L LG GT VY G+ R G D + ++
Sbjct 1381 LQTIKNADLEELRELGSGTFGTVYHGKWR--------------------GTDVAIKRIKA 1420
Query 640 VLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEYVEHGPLD 696
PS + + F+ A + + H ++ +GV GP + VTEY+ +G L
Sbjct 1421 SCFAGRPSEQERLIEDFWREACNLGHLHHPNVVAFYGVVADGPGGTLATVTEYMVNGSLK 1480
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
L+++ + ++++A A + YL KN+VH ++ N+L + + + P K
Sbjct 1481 QVLQKKDRTIDRRKRLLIAMDAAFGMEYLHGKNIVHFDLKCENLL---VNMRDPHRPICK 1537
Query 757 LSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
+ D +GL + + V +PW+APE L G ++ ++ +D + FG + E+
Sbjct 1538 VGD--LGLSKVKHQTMVSGGVRGTLPWMAPELLNGNSSLVTEKVDVFSFGIVMWEL---- 1591
Query 812 EAPLQSRSPSEKEHF---------YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
L P +K H+ + +P P +L +C EP RPSF I
Sbjct 1592 ---LTGEEPYDKMHYGAIIGGIVNNTLRPLIPSWCDPAWRSLMERCWANEPAVRPSFSDI 1648
Query 863 LRDL----TRLQPHNLA 875
++L LQP A
Sbjct 1649 AKELRTMAAALQPKTQA 1665
>sp|Q9H2K8|TAOK3_HUMAN Serine/threonine-protein kinase TAO3 OS=Homo
sapiens OX=9606 GN=TAOK3 PE=1 SV=2
Length=898
Score = 95.9 bits (237), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 72/203 (35%), Positives = 102/203 (50%), Gaps = 23/203 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956
+ ++G G FG V Y TN T E+VA+K + + G Q W+ +E+ LR L H
Sbjct 27 LHEIGHGSFGAV----YFATNAHTSEVVAIKKM-SYSGKQTHEKWQDILKEVKFLRQLKH 81
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014
+ I+YKGC E + LVMEY LGS D L H L ++ + A G+AYL
Sbjct 82 PNTIEYKGCY--LKEHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALHGLAYL 138
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071
H+ IHRD+ A N+LL VK+ DFG A + + +P +W APE
Sbjct 139 HSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFV------GTP-YWMAPEVIL 191
Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094
+ E ++ D+WS G+T EL
Sbjct 192 AMDEGQYDGKVDIWSLGITCIEL 214
>sp|Q54H46|DRKA_DICDI Probable serine/threonine-protein kinase
drkA OS=Dictyostelium discoideum OX=44689 GN=drkA PE=3 SV=1
Length=642
Score = 95.1 bits (235), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 80/278 (29%), Positives = 131/278 (47%), Gaps = 38/278 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGT--GEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHI 959
+G+G++G+V L GT G VAVK L A + + +EI++++ L H ++
Sbjct 380 IGKGNYGEVYL--------GTWRGSQVAVKKLPAHNINENILKEFHREINLMKNLRHPNV 431
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI--CEGMAYLHAQ 1017
I++ G C + + + EY+P GSL L ++ L LL I +G+ YLH
Sbjct 432 IQFLGSCLIPPD--ICICTEYMPRGSLYSILHDQALQLQWSLLIKMMIDAAKGVIYLHNS 489
Query 1018 H--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRDL + N+L+D + VK+ DFGL+ +G +P W +PE L+
Sbjct 490 TPVILHRDLKSHNLLVDENWKVKVADFGLSTIEQQG----ATMTACGTPC-WTSPEVLRS 544
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
++ +DV+SFG+ L+E T D PP + + +G G R
Sbjct 545 QRYTEKADVYSFGIILWECATRQDPYFGIPPFQVIFAVG---------------REGMRP 589
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P P P + L+ +C S RPT E + L+++
Sbjct 590 PVPQNGPPKYIQLLIDCLNENPSHRPTMEQCLERLESI 627
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 67/315 (21%), Positives = 131/315 (42%), Gaps = 43/315 (14%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVE-GSGDPEEGKMDDEDPLVPGRDRGQELRV 639
+++ D+ + TQ+ G ++++ ++ V G G+ E + G RG + V
Sbjct 352 YYKPDKNDYTQIK---DGKDIDIHQIKIGVRIGKGNYGEVYL--------GTWRGSQ--V 398
Query 640 VLKVLDPSHH---DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+K L P+H+ +I F+ +LM + H ++ G C+ P+ + TEY+ G L
Sbjct 399 AVKKL-PAHNINENILKEFHREINLMKNLRHPNVIQFLGSCLIPPDICICTEYMPRGSLY 457
Query 697 VWLRRERGHVPMAWKMVVAQQL--ASALSYLENKN--LVHGNVCGRNILLARLGLAEGTS 752
L + + + W +++ + A + YL N ++H ++ N+L+ +
Sbjct 458 SILHDQA--LQLQWSLLIKMMIDAAKGVIYLHNSTPVILHRDLKSHNLLVDE-------N 508
Query 753 PFIKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+K++D GL + ++ W +PE L + + D + FG L E C
Sbjct 509 WKVKVAD--FGLSTIEQQGATMTACGTPCWTSPEVLR--SQRYTEKADVYSFGIILWE-C 563
Query 809 FDGEAPLQSRSPSEKEHFYQRQHR---LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ P P + R+ +P+ P+ L CL P+ RP+ L
Sbjct 564 ATRQDPYFGIPPFQVIFAVGREGMRPPVPQNGPPKYIQLLIDCLNENPSHRPTMEQCLER 623
Query 866 LTRLQPHNLADVLTV 880
L + +D+ V
Sbjct 624 LESIDSSGYSDLQYV 638
>sp|Q9FE20|PBS1_ARATH Serine/threonine-protein kinase PBS1 OS=Arabidopsis
thaliana OX=3702 GN=PBS1 PE=1 SV=1
Length=456
Score = 94.0 bits (232), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 73/205 (36%), Positives = 105/205 (51%), Gaps = 22/205 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG+V Y D TG++VAVK L + G Q + E+ +L L+H +++
Sbjct 92 LGEGGFGRV----YKGRLDSTGQVVAVKQLDRN-GLQGNREFLVEVLMLSLLHHPNLVNL 146
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
G C D G++ L LV E++PLGSL D+L + ++ + A +G+ +LH +
Sbjct 147 IGYCAD-GDQRL-LVYEFMPLGSLEDHLHDLPPDKEALDWNMRMKIAAGAAKGLEFLHDK 204
Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG---HEYYRVREDGDSPVFWYAPE 1071
I+RD + N+LLD K+ DFGLAK P G H RV + APE
Sbjct 205 ANPPVIYRDFKSSNILLDEGFHPKLSDFGLAKLGPTGDKSHVSTRVM----GTYGYCAPE 260
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
+ SDV+SFGV EL+T
Sbjct 261 YAMTGQLTVKSDVYSFGVVFLELIT 285
>sp|Q1PDV6|PBL27_ARATH Serine/threonine-protein kinase PBL27 OS=Arabidopsis
thaliana OX=3702 GN=PBL27 PE=1 SV=1
Length=513
Score = 94.4 bits (233), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 74/213 (35%), Positives = 112/213 (53%), Gaps = 19/213 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG+V Y + TG++VAVK L + G Q + E+ +L L+H +++
Sbjct 89 LGEGGFGRV----YKGRLETTGQIVAVKQLDRN-GLQGNREFLVEVLMLSLLHHPNLVNL 143
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
G C D G++ L LV EY+PLGSL D+L + + + + A +G+ YLH +
Sbjct 144 IGYCAD-GDQRL-LVYEYMPLGSLEDHLHDLPPDKEPLDWSTRMTIAAGAAKGLEYLHDK 201
Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
I+RDL + N+LL + K+ DFGLAK P G + + V + APE
Sbjct 202 ANPPVIYRDLKSSNILLGDGYHPKLSDFGLAKLGPVGDKTH-VSTRVMGTYGYCAPEYAM 260
Query 1075 EYKFYYASDVWSFGVTLYELLT---HCDSSQSP 1104
+ SDV+SFGV EL+T D++++P
Sbjct 261 TGQLTLKSDVYSFGVVFLELITGRKAIDNARAP 293
Score = 54.3 bits (129), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 75/317 (24%), Positives = 124/317 (39%), Gaps = 59/317 (19%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LG+G VY+GRL G V +K LD +
Sbjct 89 LGEGGFGRVYKGRLETTGQ------------------------IVAVKQLDRNGLQGNRE 124
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--K 711
F ++S + H +L + G C G + ++V EY+ G L+ L P+ W +
Sbjct 125 FLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEYMPLGSLEDHLHDLPPDKEPLDWSTR 184
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSRE 770
M +A A L YL +K + V R++ + + L +G P KLSD G+ LG + +
Sbjct 185 MTIAAGAAKGLEYLHDK--ANPPVIYRDLKSSNILLGDGYHP--KLSDFGLAKLGPVGDK 240
Query 771 ERVE-RIPWLAPECLPGGA--NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE----- 822
V R+ C P A L+ D + FG LE+ +A +R+P E
Sbjct 241 THVSTRVMGTYGYCAPEYAMTGQLTLKSDVYSFGVVFLELITGRKAIDNARAPGEHNLVA 300
Query 823 -KEHFYQRQHRLPEPSCPQLA------------TLTSQCLTYEPTQRPSFRTILRDLTRL 869
++ + + P+ + P L + + CL + RP ++ LT L
Sbjct 301 WARPLFKDRRKFPKMADPSLQGRYPMRGLYQALAVAAMCLQEQAATRPLIGDVVTALTYL 360
Query 870 QPHNLADVLTVNPDSPA 886
T +P++P+
Sbjct 361 ASQ------TFDPNAPS 371
>sp|Q9JI11|STK4_MOUSE Serine/threonine-protein kinase 4 OS=Mus
musculus OX=10090 GN=Stk4 PE=1 SV=1
Length=487
Score = 94.4 bits (233), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V Y + TG++VA+K + + Q +EI I++ H+
Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 201 YNCVADIWSLGITAIEM 217
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q H+ +G + + +V EY G + +R + + Q
Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL +H ++ NILL G A KL+D GV +++ V
Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187
Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830
P W+APE + G N ++ D W G T +E+ +G+ P P
Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R PE QCL P QR + +L+
Sbjct 244 FRKPELWSDNFMDFVKQCLVKSPEQRATATQLLQ 277
>sp|Q9P0L2|MARK1_HUMAN Serine/threonine-protein kinase MARK1 OS=Homo
sapiens OX=9606 GN=MARK1 PE=1 SV=2
Length=795
Score = 95.5 bits (236), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 69/199 (35%), Positives = 100/199 (50%), Gaps = 13/199 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G+G+F KV L + T G VAVK + K P +E+ I++ L H +I
Sbjct 64 KTIGKGNFAKVKLARHVLT----GREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQH 1018
+K E EK+L LVMEY G + DYL H + + +QI + Y H ++
Sbjct 120 VKLFEVIET--EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 177
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRDL A N+LLD D +KI DFG + G++ G P + APE + K+
Sbjct 178 IVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTF--CGSPP--YAAPELFQGKKY 233
Query 1079 YYAS-DVWSFGVTLYELLT 1096
DVWS GV LY L++
Sbjct 234 DGPEVDVWSLGVILYTLVS 252
Score = 34.7 bits (78), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 51/236 (22%), Positives = 93/236 (39%), Gaps = 22/236 (9%)
Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K++D + + + +M ++H ++ + V +V EY G +
Sbjct 86 VAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVF 145
Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+L H M K A+ Q+ SA+ Y K +VH ++ N+LL
Sbjct 146 DYLV---AHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLL-------DGDMN 195
Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
IK++D G + +++ P+ APE G +D W G L +
Sbjct 196 IKIADFGFS-NEFTVGNKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLV-S 252
Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
G P ++ E +E + ++R+P L + L P +R S I++D
Sbjct 253 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKD 308
>sp|P38692|KIC1_YEAST Serine/threonine-protein kinase KIC1 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=KIC1 PE=1 SV=1
Length=1080
Score = 95.9 bits (237), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 66/209 (32%), Positives = 101/209 (48%), Gaps = 15/209 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
K+ +G G FG V Y N TG + A+K L D ++EI L +L
Sbjct 23 FKRTEVIGRGKFGVV----YKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQ 78
Query 957 -EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH 1015
+I +Y G + SL ++ME+ GSLR L I + + +++ + +H
Sbjct 79 ISNITRYYGSY--LKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIH 136
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ IHRD+ A NVL+ N+ VK+ DFG+A V R + +P +W APE + E
Sbjct 137 KDNVIHRDIKAANVLITNEGNVKLCDFGVAAQV--NQTSLRRQTMAGTP-YWMAPEVIME 193
Query 1076 YKFYYAS-DVWSFGVTLYELLT----HCD 1099
+Y D+WS G+T YE+ T +CD
Sbjct 194 GVYYDTKVDIWSLGITTYEIATGNPPYCD 222
Score = 41.2 bits (95), Expect = 0.065, Method: Compositional matrix adjust.
Identities = 34/128 (27%), Positives = 55/128 (43%), Gaps = 14/128 (11%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
++ E+ G L LR G + + V+ ++L AL + N++H ++ N+L+
Sbjct 97 IIMEHCAGGSLRSLLRP--GKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITN 154
Query 745 LGLAEGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800
G +KL D GV +L R+ W+APE + G T +D W
Sbjct 155 EG-------NVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGV-YYDTKVDIWSL 206
Query 801 GATLLEIC 808
G T EI
Sbjct 207 GITTYEIA 214
>sp|A8X775|DLK1_CAEBR Mitogen-activated protein kinase kinase
kinase dlk-1 OS=Caenorhabditis briggsae OX=6238 GN=dlk-1 PE=3
SV=1
Length=857
Score = 95.5 bits (236), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 71/227 (31%), Positives = 110/227 (48%), Gaps = 34/227 (15%)
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQ 1005
EI LR L H++II++ G C +VMEY P G L L + ++ Q+ + +
Sbjct 98 EIKHLRHLRHKNIIEFLGVCSKS--PCYCIVMEYCPKGQLCTVLRQKNLITRQMFSDWVK 155
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS-- 1063
+I +GM YLH IHRDL + N+L+ + +KI DFG + +++ DS
Sbjct 156 EIADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTS----------HLQKKNDSTM 205
Query 1064 -----PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
V W APE +K+ DV+SFGV L+E+LT ++P IAQ
Sbjct 206 MSFCGTVSWMAPEMIKKEPCNEKVDVYSFGVVLWEMLTR----ETP------YANIAQMA 255
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ T +L LP P++ P + L+K C + RP+F ++
Sbjct 256 IIFGVGTNILN----LPMPEEAPRGLVLLIKQCLSQKGRNRPSFSHI 298
Score = 40.4 bits (93), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 50/214 (23%), Positives = 88/214 (41%), Gaps = 22/214 (10%)
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726
H ++ GVC + P +V EY G L LR++ + V +++A + YL
Sbjct 107 HKNIIEFLGVCSKSPCYCIVMEYCPKGQLCTVLRQKNLITRQMFSDWV-KEIADGMHYLH 165
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER----IPWLAPE 782
++H ++ NIL++ AE + IK+ D G + + + W+APE
Sbjct 166 QNKVIHRDLKSPNILIS----AEDS---IKICDFGTSHLQKKNDSTMMSFCGTVSWMAPE 218
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-----LPEPS 837
+ + +D + FG L E+ E P + ++ + +PE +
Sbjct 219 MIK--KEPCNEKVDVYSFGVVLWEM-LTRETPYA--NIAQMAIIFGVGTNILNLPMPEEA 273
Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
L L QCL+ + RPSF I + +P
Sbjct 274 PRGLVLLIKQCLSQKGRNRPSFSHIRQHWEIFKP 307
>sp|Q13043|STK4_HUMAN Serine/threonine-protein kinase 4 OS=Homo
sapiens OX=9606 GN=STK4 PE=1 SV=2
Length=487
Score = 94.4 bits (233), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V Y + TG++VA+K + + Q +EI I++ H+
Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 201 YNCVADIWSLGITAIEM 217
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q H+ +G + + +V EY G + +R + + Q
Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL +H ++ NILL G A KL+D GV +++ V
Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187
Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830
P W+APE + G N ++ D W G T +E+ +G+ P P
Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R PE QCL P QR + +L+
Sbjct 244 FRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQ 277
>sp|Q96S53|TESK2_HUMAN Dual specificity testis-specific protein
kinase 2 OS=Homo sapiens OX=9606 GN=TESK2 PE=1 SV=1
Length=571
Score = 94.7 bits (234), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 76/284 (27%), Positives = 127/284 (45%), Gaps = 39/284 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G F +V + + +G+ V ALK + +R+ +E+ ++ L H +I+++
Sbjct 64 IGSGFFSEV----FKVRHRASGQ---VMALKMNTLSSNRANMLKEVQLMNRLSHPNILRF 116
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G C QG+ L + EY+ G+L L + + + A I G++YLH + H
Sbjct 117 MGVCVHQGQ--LHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFH 174
Query 1022 RDLAARNVLLDNDR---LVKIGDFGLAKAVPE---GHEYYRVREDGDSPVFWYAPECLKE 1075
RDL ++N L+ D + DFGLA+ +P+ G E V SP FW APE L++
Sbjct 175 RDLTSKNCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVV---GSP-FWMAPEVLRD 230
Query 1076 YKFYYASDVWSFGVTLYELLT--HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ +DV+S+G+ L E++ D P T+ L A M
Sbjct 231 EPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMV------------- 277
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
CP + L NC + RP+F + L+ + + Q
Sbjct 278 ----GDCPPDFLQLTFNCCNMDPKLRPSFVEIGKTLEEILSRLQ 317
Score = 63.2 bits (152), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 68/258 (26%), Positives = 111/258 (43%), Gaps = 36/258 (14%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
R GQ + + + L + ++ + LM+++SH ++ GVCV + +TEY+
Sbjct 78 RASGQVMALKMNTLSSNRANM----LKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYI 133
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR------ 744
G L+ L H+P ++ +A +A LSYL K + H ++ +N L+ R
Sbjct 134 NSGNLEQLLDSNL-HLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYS 192
Query 745 -----LGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
GLAE K+ D +G L+ V W+APE L + D +
Sbjct 193 AVVADFGLAE------KIPDVSMGSEKLA---VVGSPFWMAPEVL--RDEPYNEKADVFS 241
Query 800 FGATLLEIC--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSC-PQLATLTSQCLTYEPTQR 856
+G L EI + R+ + + QH + + C P LT C +P R
Sbjct 242 YGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGD--CPPDFLQLTFNCCNMDPKLR 299
Query 857 PSF----RTILRDLTRLQ 870
PSF +T+ L+RLQ
Sbjct 300 PSFVEIGKTLEEILSRLQ 317
>sp|A4K2T0|STK4_MACMU Serine/threonine-protein kinase 4 OS=Macaca
mulatta OX=9544 GN=STK4 PE=3 SV=1
Length=487
Score = 94.4 bits (233), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V Y + TG++VA+K + + Q +EI I++ H+
Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 201 YNCVADIWSLGITAIEM 217
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q H+ +G + + +V EY G + +R + + Q
Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL +H ++ NILL G A KL+D GV +++ V
Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187
Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830
P W+APE + G N ++ D W G T +E+ +G+ P P
Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R PE QCL P QR + +L+
Sbjct 244 FRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQ 277
>sp|A4K2Y1|STK4_CHLAE Serine/threonine-protein kinase 4 OS=Chlorocebus
aethiops OX=9534 GN=STK4 PE=3 SV=1
Length=487
Score = 94.0 bits (232), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V Y + TG++VA+K + + Q +EI I++ H+
Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 201 YNCVADIWSLGITAIEM 217
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q H+ +G + + +V EY G + +R + + Q
Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL +H ++ NILL G A KL+D GV +++ V
Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187
Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830
P W+APE + G N ++ D W G T +E+ +G+ P P
Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R PE QCL P QR + +L+
Sbjct 244 FRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQ 277
>sp|P53669|LIMK1_RAT LIM domain kinase 1 OS=Rattus norvegicus
OX=10116 GN=Limk1 PE=1 SV=1
Length=647
Score = 95.1 bits (235), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 79/296 (27%), Positives = 133/296 (45%), Gaps = 41/296 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+ T+ TGE++ +K L R+ K E+ ++R L H +++K+
Sbjct 345 LGKGCFGQA----IKVTHRETGEVMVMKELIRFDEETQRTFLK-EVKVMRCLEHPNVLKF 399
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYI 1020
G +K L + EY+ G+LR + +Q + FA+ I GMAYLH+ + I
Sbjct 400 IGVLYK--DKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNII 457
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAV---------------PEGHEYYRVREDGDSPV 1065
HRDL + N L+ +R V + DFGLA+ + P+ + Y V +
Sbjct 458 HRDLNSHNCLVRENRNVVVADFGLARLMIDEKGQSEDLRSLKKPDRKKRYTVVGNP---- 513
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+W APE + + DV+SFG+ L E++ ++ + ++ L +
Sbjct 514 YWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDF---------GLNVR 564
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
L+R P CP + + C + + RP+F L L+T+ G P
Sbjct 565 GFLDRY----CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETLRMHLAGHLP 616
Score = 65.5 bits (158), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 64/261 (25%), Positives = 114/261 (44%), Gaps = 23/261 (9%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+V+K L + F + +M + H ++ GV + +TEY++ G L
Sbjct 365 MVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGI 424
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNV----C----GRNILLARLGLAEG 750
++ P + ++ A+ +AS ++YL + N++H ++ C RN+++A GLA
Sbjct 425 IKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLAR- 483
Query 751 TSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAMDKWGFGATL 804
I L +L + +R +R W+APE + G S +D + FG L
Sbjct 484 --LMIDEKGQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMING--RSYDEKVDVFSFGIVL 539
Query 805 LEIC--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSC-PQLATLTSQCLTYEPTQRPSFRT 861
EI + + R+ + R P+C P +T +C +P +RPSF
Sbjct 540 CEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVK 599
Query 862 ILRDLTRLQPHNLADVLTVNP 882
+ + L L+ H LA L + P
Sbjct 600 LEQWLETLRMH-LAGHLPLGP 619
>sp|Q80YE4|LMTK1_MOUSE Serine/threonine-protein kinase LMTK1 OS=Mus
musculus OX=10090 GN=Aatk PE=1 SV=1
Length=1365
Score = 95.9 bits (237), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 74/220 (34%), Positives = 111/220 (50%), Gaps = 20/220 (9%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
T + L ++++G G FGKV + + + +G V VK LK Q + + +E
Sbjct 119 TDLGRHSLLYLKEIGHGWFGKV--FLGEVHSGVSGTQVVVKELKVSASVQEQMQFLEEAQ 176
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQI 1007
R L H ++++ C + LVME+ PLG L+ YL R + +A L Q++
Sbjct 177 PYRALQHSNLLQCLAQCAEV--TPYLLVMEFCPLGDLKGYLRSCRVTESMAPDPLTLQRM 234
Query 1008 -CE---GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD- 1062
CE G+ +LH +Y+H DLA RN LL D VK+GD+GL+ + E Y V D
Sbjct 235 ACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLSHC--KYREDYLVTADQLW 292
Query 1063 SPVFWYAPECLKE-------YKFYYASDVWSFGVTLYELL 1095
P+ W APE + E +S+VWS GVT++EL
Sbjct 293 VPLRWIAPELVDEVHGNLLVVDQTKSSNVWSLGVTIWELF 332
>sp|Q01389|BCK1_YEAST Serine/threonine-protein kinase BCK1/SLK1/SSP31
OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=BCK1 PE=1 SV=1
Length=1478
Score = 95.9 bits (237), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 68/207 (33%), Positives = 106/207 (51%), Gaps = 27/207 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS----------GWKQEIDILR 952
+G+G FG V L C + T TGEM+AVK ++ P++ S + E+ L+
Sbjct 1181 IGKGSFGAVYL-CLNVT---TGEMMAVKQVEV---PKYSSQNEAILSTVEALRSEVSTLK 1233
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYV---PLGSLRDYLPRHSIGLAQLLLFAQQICE 1009
L H +I++Y G + L +EYV +GSL R L + L Q+ +
Sbjct 1234 DLDHLNIVQYLGF--ENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHL--TTQVLK 1289
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
G+AYLH++ +HRD+ A N+LLD D + KI DFG+++ + + + G VFW A
Sbjct 1290 GLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGT--VFWMA 1347
Query 1070 PECLKEYKFYYAS-DVWSFGVTLYELL 1095
PE + + Y A D+WS G + E+
Sbjct 1348 PEMVDTKQGYSAKVDIWSLGCIVLEMF 1374
Score = 43.1 bits (100), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 61/248 (25%), Positives = 103/248 (42%), Gaps = 31/248 (13%)
Query 636 ELRVVLKVLDPSHHDIALAFYETA-SLMSQVSH----THLAFVHGVCVRGPENI--MVTE 688
E+ V +V P + A T +L S+VS HL V + NI + E
Sbjct 1199 EMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLE 1258
Query 689 YVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
YV G + +R R P+ + Q+ L+YL +K ++H ++ N+LL + G+
Sbjct 1259 YVAGGSVGSLIRMYGRFDEPLIKHLTT--QVLKGLAYLHSKGILHRDMKADNLLLDQDGI 1316
Query 748 AEGTSPFIKLSDPGVGLGA---LSREERVER--IPWLAPECLPGGANSLSTAMDKWGFGA 802
K+SD G+ + S + R + W+APE + S +D W G
Sbjct 1317 C-------KISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMV-DTKQGYSAKVDIWSLGC 1368
Query 803 TLLEICFDGEAP---LQSRSPSEKEHFYQRQHRLPEPSCPQLA----TLTSQCLTYEPTQ 855
+LE+ F G+ P L+ + K + +PE + P ++ C P +
Sbjct 1369 IVLEM-FAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEK 1427
Query 856 RPSFRTIL 863
RP+ +L
Sbjct 1428 RPTANELL 1435
>sp|P0DP15|SNF1_FUSVI Sucrose non-fermenting protein kinase 1
OS=Fusarium virguliforme OX=232082 GN=SNF1 PE=3 SV=1
Length=698
Score = 95.1 bits (235), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 76/204 (37%), Positives = 106/204 (52%), Gaps = 17/204 (8%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK--ALKADCGPQHRSGWKQEIDILRTLY 955
K +R LGEG FGKV L ++ GTG+ VA+K A K ++EI+ L+ L
Sbjct 63 KVLRTLGEGSFGKVKLAIHN----GTGQQVALKIIARKKLISRDMAGRVEREIEYLQLLR 118
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYL 1014
H HIIK + E + +V+EY G L DY+ +H + A+ F QQ+ + Y
Sbjct 119 HPHIIKLYTVIKTPNE--IIMVLEYAG-GELFDYIVQHGRMKEAEARRFFQQMLCAVEYC 175
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H +HRDL N+LLD + VKI DFGL+ + +G+ ++ SP + APE +
Sbjct 176 HRHKIVHRDLKPENLLLDENLNVKIADFGLSNIMTDGN---FLKTSCGSPNY-AAPEVIG 231
Query 1075 EYKFYYAS--DVWSFGVTLYELLT 1096
K Y DVWS GV LY LL
Sbjct 232 G-KLYAGPEVDVWSCGVILYVLLV 254
>sp|Q54IP4|SHKB_DICDI Dual specificity protein kinase shkB OS=Dictyostelium
discoideum OX=44689 GN=shkB PE=3 SV=1
Length=653
Score = 95.1 bits (235), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 80/280 (29%), Positives = 133/280 (48%), Gaps = 34/280 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIK 961
LG G FG V G+ VA+K L ++ + +K+E+ ++ L + H++
Sbjct 180 LGSGAFGSVYKGIV------RGKEVAIKKLTQTVFEENTMNEFKKEVSLMAKLRNPHLLL 233
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHA 1016
+ G C + L +V E +P GS+ L I + +L A+ GM +LHA
Sbjct 234 FMGAC--TAPEDLSIVTELMPKGSVHSLLRAKEDTSDFITFKRAILIARDTVLGMTWLHA 291
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ +H DL N+L+D + +VK+ DFGL+K + P+ + ++ SP++ APE L
Sbjct 292 SNILHLDLKPANLLVDQNWVVKVADFGLSKYMKPDSKD--KLLGQAGSPLY-MAPEMLVN 348
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE-LLERGERL 1134
+ DV+SF + L+ELLT Q P K + +L E ++ + R
Sbjct 349 QPYDGKVDVFSFSILLWELLTK----QEPYNKLYS---------SYPQLVEGVVNKKNRP 395
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIP--ILKTV 1172
PD P + L+ CW+ S RP+F + IL+T+
Sbjct 396 IIPDYFPTRLKDLLARCWDHYPSRRPSFAEISKQRILETI 435
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 82/387 (21%), Positives = 160/387 (41%), Gaps = 46/387 (12%)
Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
+I+ G+ T +S S D++EI + + R + R GSG
Sbjct 135 VILNGSLTEDSTSTISPDSTKNRDEEEIIRW----EIDRNEISYNREAKLGSGAF----- 185
Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
+ G RG+E+ + + F + SLM+++ + HL G C P
Sbjct 186 ---GSVYKGIVRGKEVAIKKLTQTVFEENTMNEFKKEVSLMAKLRNPHLLLFMGACT-AP 241
Query 682 ENI-MVTEYVEHGPLDVWLRRER---GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737
E++ +VTE + G + LR + + +++A+ +++L N++H ++
Sbjct 242 EDLSIVTELMPKGSVHSLLRAKEDTSDFITFKRAILIARDTVLGMTWLHASNILHLDLKP 301
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI-------PWLAPECLPGGANS 790
N+L+ + + +K++D GL + + +++ ++APE L
Sbjct 302 ANLLVDQ-------NWVVKVAD--FGLSKYMKPDSKDKLLGQAGSPLYMAPEMLVN--QP 350
Query 791 LSTAMDKWGFGATLLEICFDGE--APLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTS 846
+D + F L E+ E L S P E +++R +P+ +L L +
Sbjct 351 YDGKVDVFSFSILLWELLTKQEPYNKLYSSYPQLVEGVVNKKNRPIIPDYFPTRLKDLLA 410
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+C + P++RPSF I + R+ L D L ++ +S + + Y+ K
Sbjct 411 RCWDHYPSRRPSFAEISKQ--RILETILIDGLILD----SSARQFWSQYYMGKEEVPWNS 464
Query 907 HFGKVSLYCYDPTNDGTGEMVAVKALK 933
SLYC +N + + + +K LK
Sbjct 465 FIVNFSLYCGFESN-LSADDIKIKFLK 490
>sp|Q55CE0|MKCF_DICDI Probable serine/threonine-protein kinase
mkcF OS=Dictyostelium discoideum OX=44689 GN=mkcF PE=3 SV=1
Length=677
Score = 95.1 bits (235), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 89/325 (27%), Positives = 144/325 (44%), Gaps = 39/325 (12%)
Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923
R LT + L T P+SD K+ +K +G G +GKV YD
Sbjct 372 RILTGISTEFLGQASTTIRVIPSSDI----KKRIKFTHMVGRGQYGKVYDALYDK----- 422
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
+ V VK + P+ + QEI L H +I+KY C L +V E++
Sbjct 423 -KRVCVKVVNYST-PKEQHNVLQEIGFLTQCDHPNILKYN--CSVLYGSDLFIVSEFIQG 478
Query 984 GSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
G+L H Q+ ++ + ++YLH + IHRD+ A NV++ D VK+ DF
Sbjct 479 GTLEQASASSHVFKETQVGFIGLELLKAISYLHEKKLIHRDIKAANVMVSTDGEVKLIDF 538
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
GL +V +G + V SP ++ +PE ++ + Y SD+WSFG+ + ELL +
Sbjct 539 GLCASVEKGGSQHMV----GSP-YYMSPEMIRGEECSYPSDIWSFGICILELLF-----K 588
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
PP + +M + + G P+ +C ++ ++ C+E+ R T
Sbjct 589 KPPHR--------DSRMKAMFYNAI--NGIDFPKI-RCSIDLKDMLWQCFESNPEKRSTV 637
Query 1163 ENLI--PILKTVHEKYQGQAPSVFS 1185
+ L+ P K K Q SVF+
Sbjct 638 DKLMRHPFFKRCESK--SQMKSVFT 660
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 53/233 (23%), Positives = 100/233 (43%), Gaps = 20/233 (9%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
RV +KV++ S + ++Q H ++ + + G + +V+E+++ G L+
Sbjct 424 RVCVKVVNYSTPKEQHNVLQEIGFLTQCDHPNILKYNCSVLYGSDLFIVSEFIQGGTLEQ 483
Query 698 WLRRERGHVPMAWKM-VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
HV ++ + +L A+SYL K L+H ++ N++++ G +K
Sbjct 484 A--SASSHVFKETQVGFIGLELLKAISYLHEKKLIHRDIKAANVMVSTDGE-------VK 534
Query 757 LSDPGV--GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
L D G+ + + V +++PE + G S D W FG +LE+ F
Sbjct 535 LIDFGLCASVEKGGSQHMVGSPYYMSPEMIRG--EECSYPSDIWSFGICILELLFKKPPH 592
Query 815 LQSRSPSEKEHFYQRQHRL--PEPSCP-QLATLTSQCLTYEPTQRPSFRTILR 864
SR K FY + + P+ C L + QC P +R + ++R
Sbjct 593 RDSRM---KAMFYNAINGIDFPKIRCSIDLKDMLWQCFESNPEKRSTVDKLMR 642
>sp|A4K2Q5|STK4_OTOGA Serine/threonine-protein kinase 4 OS=Otolemur
garnettii OX=30611 GN=STK4 PE=3 SV=1
Length=487
Score = 94.0 bits (232), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V Y + TG++VA+K + + Q +EI I++ H+
Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 201 YNCVADIWSLGITAIEM 217
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q H+ +G + + +V EY G + +R + + Q
Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL +H ++ NILL G A KL+D GV +++ V
Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187
Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830
P W+APE + G N ++ D W G T +E+ +G+ P P
Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R PE QCL P QR + +L+
Sbjct 244 FRKPELWSDNFTDFVRQCLVKSPDQRATATQLLQ 277
>sp|Q5E9L6|STK4_BOVIN Serine/threonine-protein kinase 4 OS=Bos
taurus OX=9913 GN=STK4 PE=2 SV=1
Length=487
Score = 94.0 bits (232), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V Y + TG++VA+K + + Q +EI I++ H+
Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 201 YNCVADIWSLGITAIEM 217
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q H+ +G + + +V EY G + +R + + Q
Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL +H ++ NILL G A KL+D GV +++ V
Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187
Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830
P W+APE + G N ++ D W G T +E+ +G+ P P
Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R PE QCL P QR + +L+
Sbjct 244 FRKPELWSDSFMDFVKQCLVKSPEQRATATQLLQ 277
>sp|A4K2S1|STK4_LEMCA Serine/threonine-protein kinase 4 OS=Lemur
catta OX=9447 GN=STK4 PE=3 SV=1
Length=487
Score = 94.0 bits (232), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V Y + TG++VA+K + + Q +EI I++ H+
Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 201 YNCVADIWSLGITAIEM 217
Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q H+ +G + + +V EY G + +R + + Q
Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL +H ++ NILL G A KL+D GV +++ V
Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187
Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830
P W+APE + G N ++ D W G T +E+ +G+ P P
Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R PE QCL P QR + +L+
Sbjct 244 FRKPELWSDNFMDFVRQCLVKSPDQRATATQLLQ 277
>sp|Q96L34|MARK4_HUMAN MAP/microtubule affinity-regulating kinase
4 OS=Homo sapiens OX=9606 GN=MARK4 PE=1 SV=1
Length=752
Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 72/215 (33%), Positives = 105/215 (49%), Gaps = 16/215 (7%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSG 943
P P V + R L R +G+G+F KV L + TG VA+K + K P
Sbjct 50 PEEQPHVGNYRLL---RTIGKGNFAKVKLARHI----LTGREVAIKIIDKTQLNPSSLQK 102
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLL 1002
+E+ I++ L H +I+K E EK+L LVMEY G + DYL H + +
Sbjct 103 LFREVRIMKGLNHPNIVKLFEVIET--EKTLYLVMEYASAGEVFDYLVSHGRMKEKEARA 160
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
+QI + Y H ++ +HRDL A N+LLD + +KI DFG + G + G
Sbjct 161 KFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTF--CGS 218
Query 1063 SPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096
P + APE + K+ D+WS GV LY L++
Sbjct 219 PP--YAAPELFQGKKYDGPEVDIWSLGVILYTLVS 251
Score = 40.8 bits (94), Expect = 0.086, Method: Compositional matrix adjust.
Identities = 52/236 (22%), Positives = 97/236 (41%), Gaps = 22/236 (9%)
Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K++D + + + + +M ++H ++ + V +V EY G +
Sbjct 85 VAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVF 144
Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+L H M K A+ Q+ SA+ Y KN+VH ++ N+LL AE
Sbjct 145 DYLV---SHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD----AEAN--- 194
Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
IK++D G + +++ P+ APE G +D W G L +
Sbjct 195 IKIADFGFS-NEFTLGSKLDTFCGSPPYAAPELFQGKKYD-GPEVDIWSLGVILYTL-VS 251
Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
G P + E +E + ++R+P ++ + L P +R + I++D
Sbjct 252 GSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKD 307
>sp|Q9FIL7|CRCK1_ARATH Calmodulin-binding receptor-like cytoplasmic
kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CRCK1 PE=1
SV=1
Length=470
Score = 93.6 bits (231), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 68/204 (33%), Positives = 102/204 (50%), Gaps = 14/204 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK-ALKADCGPQHRSGWKQEIDILRTLYHEH 958
+ +GEG FG V D DGT +VA+K A K + G +K EI L + H +
Sbjct 150 VHQIGEGGFGTVFKGKLD---DGT--IVAIKRARKNNYGKSWLLEFKNEIYTLSKIEHMN 204
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLH 1015
++K G E EK + V+EYV G+LR++L + + +A+ L A + + YLH
Sbjct 205 LVKLYGFLEHGDEKVI--VVEYVANGNLREHLDGLRGNRLEMAERLEIAIDVAHALTYLH 262
Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
IHRD+ A N+L+ N K+ DFG A+ V E + + P+
Sbjct 263 TYTDSPIIHRDIKASNILITNKLRAKVADFGFARLVSEDLGATHISTQVKGSAGYVDPDY 322
Query 1073 LKEYKFYYASDVWSFGVTLYELLT 1096
L+ ++ SDV+SFGV L E+LT
Sbjct 323 LRTFQLTDKSDVYSFGVLLVEILT 346
Score = 56.2 bits (134), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 55/238 (23%), Positives = 102/238 (43%), Gaps = 28/238 (12%)
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWK 711
L F +S++ H +L ++G G E ++V EYV +G L L RG+ + MA +
Sbjct 188 LEFKNEIYTLSKIEHMNLVKLYGFLEHGDEKVIVVEYVANGNLREHLDGLRGNRLEMAER 247
Query 712 MVVAQQLASALSYLENKN---LVHGNVCGRNILLA-RLGLAEGTSPFIKLSDPGVGLGAL 767
+ +A +A AL+YL ++H ++ NIL+ +L F +L +G +
Sbjct 248 LEIAIDVAHALTYLHTYTDSPIIHRDIKASNILITNKLRAKVADFGFARLVSEDLGATHI 307
Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF- 826
S + + ++ P+ L L+ D + FG L+EI G P++ + P +
Sbjct 308 STQVKGS-AGYVDPDYLR--TFQLTDKSDVYSFGVLLVEI-LTGRRPIELKRPRKDRLTV 363
Query 827 ------------------YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
+ +++R ++ L S+C+T RP+ + I L
Sbjct 364 KWALRRLKDDEAVLIMDPFLKRNRAAIEVAEKMLRLASECVTPTRATRPAMKGIAEKL 421
>sp|Q9V3Q6|M3K7_DROME Mitogen-activated protein kinase kinase
kinase 7 OS=Drosophila melanogaster OX=7227 GN=Tak1 PE=2 SV=1
Length=678
Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 77/283 (27%), Positives = 131/283 (46%), Gaps = 38/283 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G +G V + ++VAVK A + ++E+ L + H +II
Sbjct 25 VGHGSYGVVCKAVW------RDKLVAVKEFFASA---EQKDIEKEVKQLSRVKHPNIIAL 75
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA--- 1016
G Q ++ L+ME+ GSL ++L + + LA + +A+Q EG+AYLHA
Sbjct 76 HGISSYQ--QATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMTP 133
Query 1017 QHYIHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ IHRD+ N+LL N R +KI DFG + + + W APE +
Sbjct 134 KPLIHRDVKPLNLLLTNKGRNLKICDFGTVA------DKSTMMTNNRGSAAWMAPEVFEG 187
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
K+ D++S+ + L+E+L S+ P K ++ Q + + +GER P
Sbjct 188 SKYTEKCDIFSWAIVLWEVL-----SRKQPFKGIDNAYTIQWK---------IYKGERPP 233
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
CP + LM CW+T RP+ + ++ ++ + + Y G
Sbjct 234 LLTTCPKRIEDLMTACWKTVPEDRPSMQYIVGVMHEIVKDYTG 276
Score = 42.7 bits (99), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 47/209 (22%), Positives = 85/209 (41%), Gaps = 15/209 (7%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLAS 720
+S+V H ++ +HG+ ++ E+ E G L +L + + +A M A+Q A
Sbjct 64 LSRVKHPNIIALHGISSYQQATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAE 123
Query 721 ALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP 777
L+YL K L+H +V N+LL G F ++D +
Sbjct 124 GLAYLHAMTPKPLIHRDVKPLNLLLTNKGRNLKICDFGTVADKSTMM-----TNNRGSAA 178
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ--SRSPSEKEHFYQRQHRLPE 835
W+APE G + + W A +L + P + + + + Y+ +
Sbjct 179 WMAPEVFEGSKYTEKCDIFSW---AIVLWEVLSRKQPFKGIDNAYTIQWKIYKGERPPLL 235
Query 836 PSCPQ-LATLTSQCLTYEPTQRPSFRTIL 863
+CP+ + L + C P RPS + I+
Sbjct 236 TTCPKRIEDLMTACWKTVPEDRPSMQYIV 264
>sp|D3ZGQ5|NEK8_RAT Serine/threonine-protein kinase Nek8 OS=Rattus
norvegicus OX=10116 GN=Nek8 PE=1 SV=1
Length=698
Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 64/203 (32%), Positives = 108/203 (53%), Gaps = 17/203 (8%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYH 956
++IR +G G FG V L C + ++V +K + + + R + E +L+ L H
Sbjct 5 ERIRVVGRGAFGIVHL-CLRKADQ---KLVIIKQIPVEQMTKEERQAAQNECQVLKLLNH 60
Query 957 EHIIKY-KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMA 1012
++I+Y + ED K+L + MEY P G+L +++ + L + +L F QI +
Sbjct 61 PNVIEYYENFLED---KALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALH 117
Query 1013 YLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
++H +HRDL +N+LLD R+ VKIGDFG++K + + Y V +P + +PE
Sbjct 118 HVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVV---GTPCY-ISPE 173
Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094
+ + SD+W+ G LYEL
Sbjct 174 LCEGKPYNQKSDIWALGCVLYEL 196
>sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens OX=9606
GN=LIMK1 PE=1 SV=3
Length=647
Score = 94.7 bits (234), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 80/292 (27%), Positives = 135/292 (46%), Gaps = 33/292 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+ T+ TGE++ +K L R+ + +E+ ++R L H +++K+
Sbjct 345 LGKGCFGQA----IKVTHRETGEVMVMKELIRFDEETQRT-FLKEVKVMRCLEHPNVLKF 399
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYI 1020
G +K L + EY+ G+LR + +Q + FA+ I GMAYLH+ + I
Sbjct 400 IGVLYK--DKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNII 457
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLA------KAVPEGHEYYRV--REDGDSPV---FWYA 1069
HRDL + N L+ ++ V + DFGLA K PEG + R+ + V +W A
Sbjct 458 HRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMA 517
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE + + DV+SFG+ L E++ ++ + ++ L + L+
Sbjct 518 PEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDF---------GLNVRGFLD 568
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
R P CP + + C + + RP+F L L+T+ G P
Sbjct 569 RY----CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHLP 616
Score = 67.4 bits (163), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 66/266 (25%), Positives = 113/266 (42%), Gaps = 33/266 (12%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+V+K L + F + +M + H ++ GV + +TEY++ G L
Sbjct 365 MVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGI 424
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL-------------LARL 745
++ P + ++ A+ +AS ++YL + N++H ++ N L LARL
Sbjct 425 IKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARL 484
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAMDKWG 799
+ E T P GL +L + +R +R W+APE + G S +D +
Sbjct 485 MVDEKTQP--------EGLRSLKKPDRKKRYTVVGNPYWMAPEMING--RSYDEKVDVFS 534
Query 800 FGATLLEIC--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSC-PQLATLTSQCLTYEPTQR 856
FG L EI + + R+ + R P+C P +T +C +P +R
Sbjct 535 FGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKR 594
Query 857 PSFRTILRDLTRLQPHNLADVLTVNP 882
PSF + L L+ H LA L + P
Sbjct 595 PSFVKLEHWLETLRMH-LAGHLPLGP 619
>sp|Q8CIP4|MARK4_MOUSE MAP/microtubule affinity-regulating kinase
4 OS=Mus musculus OX=10090 GN=Mark4 PE=1 SV=1
Length=752
Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 72/215 (33%), Positives = 105/215 (49%), Gaps = 16/215 (7%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSG 943
P P V + R L R +G+G+F KV L + T G VA+K + K P
Sbjct 50 PEEQPHVGNYRLL---RTIGKGNFAKVKLARHILT----GREVAIKIIDKTQLNPSSLQK 102
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLL 1002
+E+ I++ L H +I+K E EK+L LVMEY G + DYL H + +
Sbjct 103 LFREVRIMKGLNHPNIVKLFEVIET--EKTLYLVMEYASAGEVFDYLVSHGRMKEKEARA 160
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
+QI + Y H ++ +HRDL A N+LLD + +KI DFG + G + G
Sbjct 161 KFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTF--CGS 218
Query 1063 SPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096
P + APE + K+ D+WS GV LY L++
Sbjct 219 PP--YAAPELFQGKKYDGPEVDIWSLGVILYTLVS 251
Score = 41.2 bits (95), Expect = 0.073, Method: Compositional matrix adjust.
Identities = 52/236 (22%), Positives = 97/236 (41%), Gaps = 22/236 (9%)
Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K++D + + + + +M ++H ++ + V +V EY G +
Sbjct 85 VAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVF 144
Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+L H M K A+ Q+ SA+ Y KN+VH ++ N+LL AE
Sbjct 145 DYLV---SHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD----AEAN--- 194
Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
IK++D G + +++ P+ APE G +D W G L +
Sbjct 195 IKIADFGFS-NEFTLGSKLDTFCGSPPYAAPELFQGKKYD-GPEVDIWSLGVILYTL-VS 251
Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
G P + E +E + ++R+P ++ + L P +R + I++D
Sbjct 252 GSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKD 307
>sp|Q86SG6|NEK8_HUMAN Serine/threonine-protein kinase Nek8 OS=Homo
sapiens OX=9606 GN=NEK8 PE=1 SV=1
Length=692
Score = 94.7 bits (234), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 64/203 (32%), Positives = 108/203 (53%), Gaps = 17/203 (8%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYH 956
++IR +G G FG V L C + ++V +K + + + R + E +L+ L H
Sbjct 5 ERIRVVGRGAFGIVHL-CLRKADQ---KLVIIKQIPVEQMTKEERQAAQNECQVLKLLNH 60
Query 957 EHIIKY-KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMA 1012
++I+Y + ED K+L + MEY P G+L +++ + L + +L F QI +
Sbjct 61 PNVIEYYENFLED---KALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALH 117
Query 1013 YLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
++H +HRDL +N+LLD R+ VKIGDFG++K + + Y V +P + +PE
Sbjct 118 HVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVV---GTPCY-ISPE 173
Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094
+ + SD+W+ G LYEL
Sbjct 174 LCEGKPYNQKSDIWALGCVLYEL 196
>sp|Q5E9Y0|CDK2_BOVIN Cyclin-dependent kinase 2 OS=Bos taurus
OX=9913 GN=CDK2 PE=2 SV=1
Length=298
Score = 90.9 bits (224), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 68/207 (33%), Positives = 104/207 (50%), Gaps = 19/207 (9%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955
+K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ L
Sbjct 4 FQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYV--PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013
H +I+K E L LV E++ L D I L + + Q+ +G+A+
Sbjct 60 HPNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAF 117
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070
H+ +HRDL +N+L++ D +K+ DFGLA+A VP + V WY AP
Sbjct 118 CHSHRVLHRDLKPQNLLINADGSIKLADFGLARAFGVPVRTYTHEVV------TLWYRAP 171
Query 1071 ECLKEYKFY-YASDVWSFGVTLYELLT 1096
E L K+Y A D+WS G E++T
Sbjct 172 EILLGCKYYSTAVDIWSLGCIFAEMVT 198
Score = 35.8 bits (81), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 55/251 (22%), Positives = 103/251 (41%), Gaps = 46/251 (18%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
SL+ +++H ++ + V + +V E++ +P+ QL
Sbjct 53 SLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLL 112
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREERVER 775
L++ + ++H ++ +N+L+ A+G+ IKL+D G+ G+ + V
Sbjct 113 QGLAFCHSHRVLHRDLKPQNLLIN----ADGS---IKLADFGLARAFGVPVRTYTHEVVT 165
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQS------RSPSEKE 824
+ + APE L G STA+D W G E+ F G++ + + E
Sbjct 166 LWYRAPEIL-LGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDE 224
Query 825 HFYQRQHRLPE--PSCPQLA----------------TLTSQCLTYEPTQRPSFRTIL--- 863
+ +P+ PS P+ A +L SQ L Y+P +R S + L
Sbjct 225 VVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHP 284
Query 864 --RDLTRLQPH 872
+D+T+ PH
Sbjct 285 FFQDVTKPVPH 295
>sp|A4K2P5|STK4_COLGU Serine/threonine-protein kinase 4 OS=Colobus
guereza OX=33548 GN=STK4 PE=3 SV=1
Length=487
Score = 94.0 bits (232), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V Y + TG++VA+K + + Q +EI I++ H+
Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLQSTLKGLEYLHFM 143
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 201 YNCVADIWSLGITAIEM 217
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 53/214 (25%), Positives = 80/214 (37%), Gaps = 20/214 (9%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q H+ +G + + +V EY G + +R + V Q
Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLQSTL 134
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL +H ++ NILL G A KL+D GV +++ V
Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187
Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830
P W+APE + G N ++ D W G T +E+ +G+ P P
Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R PE QCL P QR + +L+
Sbjct 244 FRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQ 277
>sp|P46573|PBL10_ARATH Probable serine/threonine-protein kinase
PBL10 OS=Arabidopsis thaliana OX=3702 GN=PBL10 PE=1 SV=2
Length=412
Score = 92.8 bits (229), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 87/288 (30%), Positives = 132/288 (46%), Gaps = 24/288 (8%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LGEG FG V D + GTG ++AVK L D G Q W E++ L H
Sbjct 75 LGEGGFGSVFKGWIDEQTLTASKPGTGVVIAVKKLNQD-GWQGHQEWLAEVNYLGQFSHP 133
Query 958 HIIKYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGM 1011
+++K G C ED+ LV E++P GSL ++L R L L A +G+
Sbjct 134 NLVKLIGYCLEDEHR---LLVYEFMPRGSLENHLFRRGSYFQPLSWTLRLKVALGAAKGL 190
Query 1012 AYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
A+LH I+RD N+LLD++ K+ DFGLAK P G + + V + A
Sbjct 191 AFLHNAETSVIYRDFKTSNILLDSEYNAKLSDFGLAKDGPTGDKSH-VSTRIMGTYGYAA 249
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT---HCDSSQSPPTKFLELIGIAQGQMTVLR-LT 1125
PE L SDV+S+GV L E+L+ D ++ P + +L+ A+ + R L
Sbjct 250 PEYLATGHLTTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQ--KLVEWARPLLANKRKLF 307
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+++ + + C+V L C E RP ++ L+ +
Sbjct 308 RVIDNRLQDQYSMEEACKVATLALRCLTFEIKLRPNMNEVVSHLEHIQ 355
Score = 59.7 bits (143), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 86/348 (25%), Positives = 146/348 (42%), Gaps = 66/348 (19%)
Query 568 RASPRTL-------NLSQLSFH--RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618
R +PRT NL +F + + S LG+G +V++G +
Sbjct 39 RTNPRTEGEILQSPNLKSFTFAELKAATRNFRPDSVLGEGGFGSVFKGWI---------- 88
Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678
DE L + G + + +K L+ + + + Q SH +L + G C+
Sbjct 89 ----DEQTLTASKP-GTGVVIAVKKLNQDGWQGHQEWLAEVNYLGQFSHPNLVKLIGYCL 143
Query 679 RGPENIMVTEYVEHGPLDVWL-RRERGHVPMAW--KMVVAQQLASALSYLEN--KNLVHG 733
++V E++ G L+ L RR P++W ++ VA A L++L N ++++
Sbjct 144 EDEHRLLVYEFMPRGSLENHLFRRGSYFQPLSWTLRLKVALGAAKGLAFLHNAETSVIYR 203
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVE-RI----PWLAPECLPGG 787
+ NILL + KLSD G+ G + V RI + APE L G
Sbjct 204 DFKTSNILL-------DSEYNAKLSDFGLAKDGPTGDKSHVSTRIMGTYGYAAPEYLATG 256
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--------------------EHFY 827
L+T D + +G LLE+ A ++R P E+ ++
Sbjct 257 --HLTTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLLANKRKLFRVIDNRL 314
Query 828 QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
Q Q+ + E +C ++ATL +CLT+E RP+ ++ L +Q N A
Sbjct 315 QDQYSMEE-AC-KVATLALRCLTFEIKLRPNMNEVVSHLEHIQTLNEA 360
>sp|Q9FX43|M2K9_ARATH Mitogen-activated protein kinase kinase
9 OS=Arabidopsis thaliana OX=3702 GN=MKK9 PE=1 SV=1
Length=310
Score = 91.3 bits (225), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 65/208 (31%), Positives = 104/208 (50%), Gaps = 20/208 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+K+ LG G+ G V Y + T E+ A+K + D P +E++ILR
Sbjct 47 LEKLNVLGCGNGGIV----YKVRHKTTSEIYALKTVNGDMDPIFTRQLMREMEILRRTDS 102
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016
+++K G E + ++MEY+ G+L R + +L FA+QI +G++YLHA
Sbjct 103 PYVVKCHGIFEKPVVGEVSILMEYMDGGTLESL--RGGVTEQKLAGFAKQILKGLSYLHA 160
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---FWYAPE-- 1071
+HRD+ N+LL++ VKI DFG++K + R + +S V + +PE
Sbjct 161 LKIVHRDIKPANLLLNSKNEVKIADFGVSKIL------VRSLDSCNSYVGTCAYMSPERF 214
Query 1072 ---CLKEYKFYYASDVWSFGVTLYELLT 1096
YA D+WSFG+ + ELL
Sbjct 215 DSESSGGSSDIYAGDIWSFGLMMLELLV 242
>sp|Q54QQ1|PHG2_DICDI Serine/threonine-protein kinase phg2 OS=Dictyostelium
discoideum OX=44689 GN=phg2 PE=1 SV=1
Length=1387
Score = 95.5 bits (236), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 71/292 (24%), Positives = 133/292 (46%), Gaps = 34/292 (12%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLY 955
L+ I+ +G G + KV Y + VA+K ++ ++ + +K+E DIL T+
Sbjct 807 LEYIKRIGSGTYSKVYKGKY------RDKFVAIKTMRGSNMTTEQIESFKKECDILSTIQ 860
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAY 1013
+I + G C ++ + L +V+EY G+L L P + + ++ EG+ Y
Sbjct 861 SPLLISFYGSCIEESQ--LSMVVEYCSKGTLHKVLNNPLLDFDWDKWFKWMTEVVEGVRY 918
Query 1014 LHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
LH+ + +HRDL N+L+ +D K+ DFGL + + + G + + APE
Sbjct 919 LHSMNPPMVHRDLKTLNILISSDWTAKLCDFGLTRTMTMTNVSTLGMLRGT--MAYTAPE 976
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSS-------QSPPTKFLELIGIAQGQMTVLRL 1124
F SDV+S GV ++E + C S + P + +++I + ++
Sbjct 977 IYDGLLFNTKSDVYSLGVIMWEAIQRCISGVYLRPFHEHPISMDIQIIILTSKNKVRPKI 1036
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
+E CP ++ L+ CW+ RP + ++ IL T+ + +
Sbjct 1037 SE------------NCPEQLKTLITRCWDENPDKRPNCDEILEILLTMKQAH 1076
>sp|Q7SY52|STK10_DANRE Serine/threonine-protein kinase 10 OS=Danio
rerio OX=7955 GN=stk10 PE=2 SV=1
Length=974
Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 63/202 (31%), Positives = 104/202 (51%), Gaps = 17/202 (8%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I +LG+G FGKV Y N TG + A K ++ + + EIDIL + H++I
Sbjct 40 IGELGDGAFGKV----YKAQNKETGVLAAAKVIETK-SEEELEDYMVEIDILASCNHQYI 94
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQ 1017
+K + L +++E+ P G++ + GL Q+ + +Q+ E + YLH+
Sbjct 95 VKLLDAF--FFDNKLSIMIEFCPGGAVDAIMLELDRGLQEPQIRVICKQMLEALQYLHSM 152
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP-----EC 1072
IHRDL A N+LL D +K+ DFG++ + + + R+ +W AP E
Sbjct 153 KIIHRDLKAGNILLTLDGDIKLADFGVS---AKNTKTLQRRDSFIGTPYWMAPEVVMCET 209
Query 1073 LKEYKFYYASDVWSFGVTLYEL 1094
+K+ + Y +D+WS G+TL EL
Sbjct 210 MKDAPYDYKADIWSLGITLIEL 231
Score = 42.4 bits (98), Expect = 0.036, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 45/103 (44%), Gaps = 14/103 (14%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV---GLGALSR 769
V+ +Q+ AL YL + ++H ++ NILL G IKL+D GV L R
Sbjct 137 VICKQMLEALQYLHSMKIIHRDLKAGNILLTLDG-------DIKLADFGVSAKNTKTLQR 189
Query 770 EERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808
+ P W+APE C D W G TL+E+
Sbjct 190 RDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIELA 232
>sp|P46549|SULU_CAEEL Serine/threonine-protein kinase SULU OS=Caenorhabditis
elegans OX=6239 GN=kin-18 PE=1 SV=1
Length=982
Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 69/209 (33%), Positives = 106/209 (51%), Gaps = 24/209 (11%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDI 950
+RY + +R++G G FG V + YD N+ T VA+K + G Q W +E+
Sbjct 28 QRY-QDLREIGHGSFGAV-YFAYDKKNEQT---VAIKKMNF-SGKQAVEKWNDILKEVSF 81
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQIC 1008
L T+ H HI+ YK C + + LVMEY +GS D + G+ ++ + A Q
Sbjct 82 LNTVVHPHIVDYKACF--LKDTTCWLVMEYC-IGSAADIVDVLRKGMREVEIAAICSQTL 138
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+ + YLH+ IHRD+ A N+LL + +VK+ DFG A V + +P F+
Sbjct 139 DALRYLHSLKRIHRDIKAGNILLSDHAIVKLADFGSASLVDPAQTFI------GTP-FFM 191
Query 1069 APE---CLKEYKFYYASDVWSFGVTLYEL 1094
APE + E + +D+WS G+T EL
Sbjct 192 APEVILAMDEGHYTDRADIWSLGITCIEL 220
>sp|P0C5E2|LRL12_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE
PROTEIN KINASE-like 1.2 OS=Arabidopsis thaliana
OX=3702 GN=LRK10L-1.2 PE=2 SV=3
Length=651
Score = 94.4 bits (233), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 82/295 (28%), Positives = 134/295 (45%), Gaps = 18/295 (6%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
++LG+G FG V Y DG VAVK L D + ++ E++IL L H +++
Sbjct 345 KELGDGGFGTVY---YGKLKDGRS--VAVKRL-YDNNFKRAEQFRNEVEILTGLRHPNLV 398
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PR---HSIGLAQLLLFAQQICEGMAYLH 1015
GC Q + L LV EYV G+L D+L P+ S+ + L A + + YLH
Sbjct 399 ALFGCSSKQS-RDLLLVYEYVANGTLADHLHGPQANPSSLPWSIRLKIAVETASALKYLH 457
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
A IHRD+ + N+LLD + VK+ DFGL++ P + G + P+
Sbjct 458 ASKIIHRDVKSNNILLDQNFNVKVADFGLSRLFPMDKTHVSTAPQGTPG--YVDPDYHLC 515
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERG--- 1131
Y+ SDV+SF V L EL++ + + P + + L +A ++ L ++++
Sbjct 516 YQLSNKSDVYSFAVVLMELISSLPAVDITRPRQEINLSNMAVVKIQNHELRDMVDPSLGF 575
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
+ R + V L C +++ RP ++ L + G V V
Sbjct 576 DTDTRVRQTVIAVAELAFQCLQSDKDLRPCMSHVQDTLTRIQNNGFGSEMDVVDV 630
Score = 54.7 bits (130), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 69/282 (24%), Positives = 115/282 (41%), Gaps = 47/282 (17%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM-VTEYVEHGPLDV 697
V +K L ++ A F +++ + H +L + G + +++ V EYV +G L
Sbjct 366 VAVKRLYDNNFKRAEQFRNEVEILTGLRHPNLVALFGCSSKQSRDLLLVYEYVANGTLAD 425
Query 698 WLRRERGH---VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
L + + +P + ++ +A + ASAL YL ++H +V NILL + +
Sbjct 426 HLHGPQANPSSLPWSIRLKIAVETASALKYLHASKIIHRDVKSNNILLDQ-------NFN 478
Query 755 IKLSDPGVGLGALSREERVERI-PWLAPECLPGGAN-------SLSTAMDKWGFGATLLE 806
+K++D G LSR +++ AP+ PG + LS D + F L+E
Sbjct 479 VKVADFG-----LSRLFPMDKTHVSTAPQGTPGYVDPDYHLCYQLSNKSDVYSFAVVLME 533
Query 807 I-----CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL---------------ATLTS 846
+ D P Q + S + H L + P L A L
Sbjct 534 LISSLPAVDITRPRQEINLSNMAVVKIQNHELRDMVDPSLGFDTDTRVRQTVIAVAELAF 593
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLA---DVLTVNPDSP 885
QCL + RP + LTR+Q + DV+ VN P
Sbjct 594 QCLQSDKDLRPCMSHVQDTLTRIQNNGFGSEMDVVDVNKSGP 635
>sp|Q9SAJ2|RAF20_ARATH RAF-like serine/threonine-protein kinase
20 OS=Arabidopsis thaliana OX=3702 GN=RAF20 PE=1 SV=1
Length=1248
Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 88/297 (30%), Positives = 131/297 (44%), Gaps = 39/297 (13%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---- 946
+ L+++R+LG G FG V + G VA+K +K C S ++
Sbjct 958 IIKNEDLEELRELGSGTFGTVYHGKW------RGSDVAIKRIKKSCFAGRSSEQERLTGE 1011
Query 947 ---EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLL 1001
E +IL L+H +++ + G +D +L V EY+ GSLR L R L + L
Sbjct 1012 FWGEAEILSKLHHPNVVAFYGVVKDGPGGTLATVTEYMVDGSLRHVLVRKDRHLDRRKRL 1071
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDR-LVKIGDFGLAKAVPEGHEYYRV 1057
+ A GM YLH+++ +H DL N+L+ D R + K+GDFGL+K V
Sbjct 1072 IIAMDAAFGMEYLHSKNTVHFDLKCDNLLVNLKDPSRPICKVGDFGLSKIKRNTLVSGGV 1131
Query 1058 REDGDSPVFWYAPECLK--EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
R G P W APE L K DV+SFG+ L+E+LT + P + I
Sbjct 1132 R--GTLP--WMAPELLNGSSSKVSEKVDVFSFGIVLWEILTGEE-----PYANMHYGAII 1182
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
G ++ R P C E LM+ CW RP+F + L+ +
Sbjct 1183 GG---------IVNNTLRPTIPGFCDDEWRTLMEECWAPNPMARPSFTEIAGRLRVM 1230
Score = 79.3 bits (194), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 79/301 (26%), Positives = 125/301 (42%), Gaps = 58/301 (19%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ +++ +L LG GT VY G+ R D ++ + GR QE
Sbjct 959 IKNEDLEELRELGSGTFGTVYHGKWR---GSDVAIKRI--KKSCFAGRSSEQER------ 1007
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEYVEHGPLDVWLRR 701
+ F+ A ++S++ H ++ +GV GP + VTEY+ G L L R
Sbjct 1008 -------LTGEFWGEAEILSKLHHPNVVAFYGVVKDGPGGTLATVTEYMVDGSLRHVLVR 1060
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
+ H+ ++++A A + YL +KN VH ++ N+L + L + + P K+ D
Sbjct 1061 KDRHLDRRKRLIIAMDAAFGMEYLHSKNTVHFDLKCDNLL---VNLKDPSRPICKVGD-- 1115
Query 762 VGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
GL + R V +PW+APE L G ++ +S +D + FG L EI GE P
Sbjct 1116 FGLSKIKRNTLVSGGVRGTLPWMAPELLNGSSSKVSEKVDVFSFGIVLWEI-LTGEEP-- 1172
Query 817 SRSPSEKEHFYQRQH----------RLPEPSCP-----QLATLTSQCLTYEPTQRPSFRT 861
Y H P+ P + TL +C P RPSF
Sbjct 1173 ----------YANMHYGAIIGGIVNNTLRPTIPGFCDDEWRTLMEECWAPNPMARPSFTE 1222
Query 862 I 862
I
Sbjct 1223 I 1223
>sp|Q6ZMQ8|LMTK1_HUMAN Serine/threonine-protein kinase LMTK1 OS=Homo
sapiens OX=9606 GN=AATK PE=1 SV=2
Length=1374
Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 69/220 (31%), Positives = 106/220 (48%), Gaps = 20/220 (9%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG-TGEMVAVKALKADCGPQHRSGWKQEI 948
T + L ++++G G FGKV L N G + V VK L+A Q + + +E+
Sbjct 118 TDVGRHSLLYLKEIGRGWFGKVFL---GEVNSGISSAQVVVKELQASASVQEQMQFLEEV 174
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA------QLLL 1002
R L H ++++ C + LVME+ PLG L+ YL + + L
Sbjct 175 QPYRALKHSNLLQCLAQCAEV--TPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPRTLQR 232
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
A ++ G+ +LH +++H DLA RN LL D VKIGD+GLA +Y+ +
Sbjct 233 MACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCK-YREDYFVTADQLW 291
Query 1063 SPVFWYAPECLKEYKFYY-------ASDVWSFGVTLYELL 1095
P+ W APE + E + +VWS GVT++EL
Sbjct 292 VPLRWIAPELVDEVHSNLLVVDQTKSGNVWSLGVTIWELF 331
Score = 35.0 bits (79), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 60/248 (24%), Positives = 99/248 (40%), Gaps = 31/248 (13%)
Query 638 RVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+VV+K L S + F E + H++L C ++V E+ G L
Sbjct 152 QVVVKELQASASVQEQMQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLK 211
Query 697 VWLRRERGHVPMAWKMVVAQQLASALS----YLENKNLVHGNVCGRNILLARLGLAEGTS 752
+LR R MA Q++A ++ +L N VH ++ RN LL A+ T
Sbjct 212 GYLRSCRVAESMAPDPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLT----ADLT- 266
Query 753 PFIKLSDPGVGLGALSREERVER----IP--WLAPECLPGGANSL-----STAMDKWGFG 801
+K+ D G+ + V +P W+APE + ++L + + + W G
Sbjct 267 --VKIGDYGLAHCKYREDYFVTADQLWVPLRWIAPELVDEVHSNLLVVDQTKSGNVWSLG 324
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTS-------QCLTYEPT 854
T+ E+ G P S + + R+ +L P PQL S Q +P
Sbjct 325 VTIWELFELGTQPYPQHSDQQVLAYTVREQQLKLPK-PQLQLTLSDRWYEVMQFCWLQPE 383
Query 855 QRPSFRTI 862
QRP+ +
Sbjct 384 QRPTAEEV 391
>sp|Q9SIT1|TMK3_ARATH Receptor-like kinase TMK3 OS=Arabidopsis
thaliana OX=3702 GN=TMK3 PE=1 SV=1
Length=943
Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 69/205 (34%), Positives = 99/205 (48%), Gaps = 21/205 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
LG G FG V +DGT +AVK +++ + + +K EI +L + H H++
Sbjct 591 LGRGGFGTV---YKGELHDGT--KIAVKRMESSVVSDKGLTEFKSEITVLTKMRHRHLVA 645
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQLLLFAQQICEGMAYLH 1015
G C D E+ LV EY+P G+L +L R + + L A + G+ YLH
Sbjct 646 LLGYCLDGNER--LLVYEYMPQGTLSQHLFHWKEEGRKPLDWTRRLAIALDVARGVEYLH 703
Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APE 1071
Q +IHRDL N+LL +D K+ DFGL + P+G R G F Y APE
Sbjct 704 TLAHQSFIHRDLKPSNILLGDDMRAKVSDFGLVRLAPDGKYSIETRVAG---TFGYLAPE 760
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
+ D++S GV L EL+T
Sbjct 761 YAVTGRVTTKVDIFSLGVILMELIT 785
Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 63/249 (25%), Positives = 101/249 (41%), Gaps = 44/249 (18%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--RERGHVPMAW-- 710
F ++++++ H HL + G C+ G E ++V EY+ G L L +E G P+ W
Sbjct 628 FKSEITVLTKMRHRHLVALLGYCLDGNERLLVYEYMPQGTLSQHLFHWKEEGRKPLDWTR 687
Query 711 KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--- 764
++ +A +A + YL ++ +H ++ NILL G K+SD G+
Sbjct 688 RLAIALDVARGVEYLHTLAHQSFIHRDLKPSNILL-------GDDMRAKVSDFGLVRLAP 740
Query 765 -GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
G S E RV +LAPE G ++T +D + G L+E+ G L P +
Sbjct 741 DGKYSIETRVAGTFGYLAPEYAVTG--RVTTKVDIFSLGVILMEL-ITGRKALDETQPED 797
Query 823 KEHFYQRQHRLPEP----------------------SCPQLATLTSQCLTYEPTQRPSFR 860
H R+ S ++ L C EP QRP
Sbjct 798 SVHLVTWFRRVAASKDENAFKNAIDPNISLDDDTVASIEKVWELAGHCCAREPYQRPDMA 857
Query 861 TILRDLTRL 869
I+ L+ L
Sbjct 858 HIVNVLSSL 866
>sp|O08679|MARK2_RAT Serine/threonine-protein kinase MARK2 OS=Rattus
norvegicus OX=10116 GN=Mark2 PE=1 SV=1
Length=722
Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 76/232 (33%), Positives = 115/232 (50%), Gaps = 18/232 (8%)
Query 870 QPHNLADVLTVNPDSPASD--PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+P + +++L + ++D P + + R LK I G+G+F KV L + T G+ V
Sbjct 27 KPSSKSNMLRGRNSATSADEQPHIGNYRLLKTI---GKGNFAKVKLARHILT----GKEV 79
Query 928 AVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
AVK + K +E+ I++ L H +I+K E EK+L LVMEY G +
Sbjct 80 AVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIET--EKTLYLVMEYASGGEV 137
Query 987 RDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
DYL H + + +QI + Y H + +HRDL A N+LLD D +KI DFG +
Sbjct 138 FDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFS 197
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096
G++ G P + APE + K+ DVWS GV LY L++
Sbjct 198 NEFTFGNKLDTF--CGSPP--YAAPELFQGKKYDGPEVDVWSLGVILYTLVS 245
Score = 40.8 bits (94), Expect = 0.089, Method: Compositional matrix adjust.
Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 22/236 (9%)
Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K++D + + + + +M ++H ++ + V +V EY G +
Sbjct 79 VAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVF 138
Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+L H M K A+ Q+ SA+ Y K +VH ++ N+LL
Sbjct 139 DYLV---AHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLL-------DADMN 188
Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
IK++D G + +++ P+ APE G +D W G L +
Sbjct 189 IKIADFGFS-NEFTFGNKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLV-S 245
Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
G P ++ E +E + ++R+P L + L P++R + I++D
Sbjct 246 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKD 301
>sp|Q9LK43|TMK4_ARATH Receptor-like kinase TMK4 OS=Arabidopsis
thaliana OX=3702 GN=TMK4 PE=1 SV=1
Length=928
Score = 94.7 bits (234), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 73/205 (36%), Positives = 103/205 (50%), Gaps = 21/205 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG G FG V Y + +DGT AVK ++ A G + S ++ EI +L + H H++
Sbjct 584 LGRGGFGVV--YAGE-LHDGT--KTAVKRMECAAMGNKGMSEFQAEIAVLTKVRHRHLVA 638
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYLH 1015
G C + E+ LV EY+P G+L +L S + Q + A + G+ YLH
Sbjct 639 LLGYCVNGNER--LLVYEYMPQGNLGQHLFEWSELGYSPLTWKQRVSIALDVARGVEYLH 696
Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APE 1071
+ Q +IHRDL N+LL +D K+ DFGL K P+G R G F Y APE
Sbjct 697 SLAQQSFIHRDLKPSNILLGDDMRAKVADFGLVKNAPDGKYSVETRLAG---TFGYLAPE 753
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
+ DV++FGV L E+LT
Sbjct 754 YAATGRVTTKVDVYAFGVVLMEILT 778
Score = 68.2 bits (165), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 64/235 (27%), Positives = 101/235 (43%), Gaps = 42/235 (18%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR--ERGHVPMAWK- 711
F +++++V H HL + G CV G E ++V EY+ G L L E G+ P+ WK
Sbjct 621 FQAEIAVLTKVRHRHLVALLGYCVNGNERLLVYEYMPQGNLGQHLFEWSELGYSPLTWKQ 680
Query 712 -MVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
+ +A +A + YL + ++ +H ++ NILL G K++D G+ A
Sbjct 681 RVSIALDVARGVEYLHSLAQQSFIHRDLKPSNILL-------GDDMRAKVADFGLVKNAP 733
Query 768 SREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ VE +LAPE G ++T +D + FG L+EI G L P E
Sbjct 734 DGKYSVETRLAGTFGYLAPEYAATG--RVTTKVDVYAFGVVLMEI-LTGRKALDDSLPDE 790
Query 823 KEHFYQ-------RQHRLPEP-------------SCPQLATLTSQCLTYEPTQRP 857
+ H + +P+ S ++A L C EP QRP
Sbjct 791 RSHLVTWFRRILINKENIPKALDQTLEADEETMESIYRVAELAGHCTAREPQQRP 845
>sp|O64768|RAF24_ARATH RAF-like serine/threonine-protein kinase
24 OS=Arabidopsis thaliana OX=3702 GN=RAF24 PE=1 SV=1
Length=1257
Score = 95.1 bits (235), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 93/297 (31%), Positives = 135/297 (45%), Gaps = 40/297 (13%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-----GPQHR--SG 943
V L+++++LG G FG V Y GT VA+K +K C Q R S
Sbjct 968 VIKNDDLEELKELGSGTFGTV----YHGKWRGTD--VAIKRIKRSCFIGRSSEQERLTSE 1021
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLL 1001
+ E +IL L+H +++ + G +D +L V EY+ GSLR L RH + + L
Sbjct 1022 FWHEAEILSKLHHPNVMAFYGVVKDGPGGTLATVTEYMVNGSLRHVLLSNRH-LDRRKRL 1080
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDR-LVKIGDFGLAKAVPEGHEYYRV 1057
+ A GM YLH++ +H DL N+L+ D R + K+GDFGL+K V
Sbjct 1081 IIAMDAAFGMEYLHSKSIVHFDLKCDNLLVNLKDPARPICKVGDFGLSKIKRNTLVTGGV 1140
Query 1058 REDGDSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
R G P W APE L K DV+SFG+ L+E+LT + P + I
Sbjct 1141 R--GTLP--WMAPELLSGSSSKVSEKVDVFSFGIVLWEILTGEE-----PYANMHYGAII 1191
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
G ++ R P+ C E LM+ CW + RP F + L+T+
Sbjct 1192 GG---------IVNNTLRPTVPNYCDPEWRMLMEQCWAPDPFVRPAFPEIARRLRTM 1239
Score = 79.3 bits (194), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 84/331 (25%), Positives = 135/331 (41%), Gaps = 59/331 (18%)
Query 564 MRGARASPRTLNLS------------QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
++GA ++ TLN S + ++ +L LG GT VY G+ R
Sbjct 937 IKGAESTDATLNAGVPLIDFMAADSGMRSLQVIKNDDLEELKELGSGTFGTVYHGKWR-- 994
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
G K + GR QE + F+ A ++S++ H ++
Sbjct 995 --GTDVAIKRIKRSCFI-GRSSEQER-------------LTSEFWHEAEILSKLHHPNVM 1038
Query 672 FVHGVCVRGPENIM--VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729
+GV GP + VTEY+ +G L L R H+ ++++A A + YL +K+
Sbjct 1039 AFYGVVKDGPGGTLATVTEYMVNGSLRHVLLSNR-HLDRRKRLIIAMDAAFGMEYLHSKS 1097
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECL 784
+VH ++ N+L+ L + P K+ D GL + R V +PW+APE L
Sbjct 1098 IVHFDLKCDNLLV---NLKDPARPICKVGD--FGLSKIKRNTLVTGGVRGTLPWMAPELL 1152
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF---------YQRQHRLPE 835
G ++ +S +D + FG L EI L P H+ + +P
Sbjct 1153 SGSSSKVSEKVDVFSFGIVLWEI-------LTGEEPYANMHYGAIIGGIVNNTLRPTVPN 1205
Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
P+ L QC +P RP+F I R L
Sbjct 1206 YCDPEWRMLMEQCWAPDPFVRPAFPEIARRL 1236
>sp|Q54WS5|ROCO6_DICDI Probable serine/threonine-protein kinase
roco6 OS=Dictyostelium discoideum OX=44689 GN=roco6 PE=3 SV=1
Length=2147
Score = 95.1 bits (235), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 85/292 (29%), Positives = 139/292 (48%), Gaps = 49/292 (17%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--DCGPQHRSGWKQEIDILRTLYHEHII 960
+G G GK+ + T MVAVK L+ + P+ S +++EI ++ L H +++
Sbjct 1362 IGRGASGKIYRANLNDT------MVAVKQLEVVGEDAPRIFSEFRREIHVMSDLKHSNVV 1415
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IG------LAQLLLFAQQICEGMAY 1013
G +VMEY+ G L +L HS IG A +L A I +GM +
Sbjct 1416 NLLGFTL----SPFTMVMEYIDCGDLHKFL--HSPIGDQLNGNWALILKLALDIAKGMEF 1469
Query 1014 LHAQH--YIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
LH+ +HRDL + NVLL D K+GDFGL+ + +++R + W
Sbjct 1470 LHSVTPPLLHRDLKSPNVLLSMKDGVYTAKVGDFGLSSRMFIQALKHKLRNFPVGNITWV 1529
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
APE L+E ++ SDV++FG+ L+ELLT + P +F +++ L E
Sbjct 1530 APEILREEEYTVKSDVYAFGLILHELLTR----KHPYREF---------NYSMVSLQE-- 1574
Query 1129 ERGERLPRPDKCPC--------EVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ + RP P E L+++CW+++ RPTF ++ +K +
Sbjct 1575 DAIKNGLRPTISPSYTQTVTGHEYCGLIQDCWDSDIDRRPTFNKIVKRIKQI 1626
>sp|Q9V422|RYK2_DROME Tyrosine-protein kinase Dnt OS=Drosophila
melanogaster OX=7227 GN=dnt PE=2 SV=2
Length=584
Score = 94.0 bits (232), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 71/267 (27%), Positives = 120/267 (45%), Gaps = 24/267 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
L EG FG+V Y+ T D V VK + QE +L H I+
Sbjct 323 LQEGTFGRVYRGTYNDTQD-----VLVKTVAQHASQMQVLLLLQEGMLLYGASHPGILSV 377
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
G + L +L+ +L ++ Q+++ A Q+ + +LH+
Sbjct 378 LGVSIEDHTTPFVLYPALNNTRNLKQFLLDPACARTVTTIQIVMMASQLSMALDHLHSHG 437
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+H+D+A RN ++D+ VK+ D L++ + +Y + + + PV W + E L+ +F
Sbjct 438 VVHKDIATRNCVIDDQLRVKLSDSSLSRDLFPS-DYNCLGDSENRPVKWMSLEALQHKQF 496
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
ASD W+FGV ++EL C S++ P ++ + L+ G RL +P
Sbjct 497 SEASDSWAFGVLMWEL---CTSAKQP-----------YAEVDPFEMEHYLKDGYRLAQPF 542
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENL 1165
CP E++ +M CW + RPTF L
Sbjct 543 NCPDELFTIMAYCWALLPAERPTFAQL 569
Score = 64.3 bits (155), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 44/157 (28%), Positives = 73/157 (46%), Gaps = 19/157 (12%)
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-------L 764
+++A QL+ AL +L + +VH ++ RN ++ +KLSD +
Sbjct 420 VMMASQLSMALDHLHSHGVVHKDIATRNCVI-------DDQLRVKLSDSSLSRDLFPSDY 472
Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
L E + W++ E L S A D W FG + E+C + P P E E
Sbjct 473 NCLGDSEN-RPVKWMSLEALQH--KQFSEASDSWAFGVLMWELCTSAKQPYAEVDPFEME 529
Query 825 HFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859
H+ + +RL +P +CP +L T+ + C P +RP+F
Sbjct 530 HYLKDGYRLAQPFNCPDELFTIMAYCWALLPAERPTF 566
>sp|Q32MK0|MYLK3_HUMAN Myosin light chain kinase 3 OS=Homo sapiens
OX=9606 GN=MYLK3 PE=1 SV=3
Length=819
Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 72/202 (36%), Positives = 101/202 (50%), Gaps = 23/202 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG+V + T TG +A K +K + R K EI+I+ L H ++I+
Sbjct 521 LGGGRFGQV----HRCTEKSTGLPLAAKIIKVKSA-KDREDVKNEINIMNQLSHVNLIQL 575
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020
E + S LVMEYV G L D + L +L +LF +QICEG+ YLH + +
Sbjct 576 YDAFESK--HSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYIL 633
Query 1021 HRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVRE----DGDSPVFWYAPECLK 1074
H DL N+L N +KI DFGLA+ Y+ RE + +P F APE +
Sbjct 634 HLDLKPENILCVNQTGHQIKIIDFGLAR-------RYKPREKLKVNFGTPEF-LAPEVVN 685
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ +D+WS GV Y LL+
Sbjct 686 YEFVSFPTDMWSVGVITYMLLS 707
>sp|Q6Z8C8|CDKF4_ORYSJ Cyclin-dependent kinase F-4 OS=Oryza sativa
subsp. japonica OX=39947 GN=CDKF-4 PE=2 SV=1
Length=459
Score = 92.8 bits (229), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 67/206 (33%), Positives = 101/206 (49%), Gaps = 21/206 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
K I+++G+G FG V + N GE+VAVK +K +E+ LR + H
Sbjct 4 FKMIKEVGDGTFGSV----WRAINKQNGEVVAVKKMKRKYYSFEECMSLREVKSLRRMNH 59
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLH 1015
+I+K K + L +MEY+ + R A++ + QI + +AY+H
Sbjct 60 PNIVKLKEVIREND--ILYFIMEYMECNLYQLMKDRVKPFSEAEVRNWCFQIFQALAYMH 117
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAK---AVPEGHEYYRVREDGDSPVFWY-APE 1071
+ Y HRDL N+L+ D ++K+ DFGLA+ +VP EY R WY APE
Sbjct 118 QRGYFHRDLKPENLLVSKD-VIKLADFGLAREVTSVPPYTEYVSTR--------WYRAPE 168
Query 1072 CLKEYKFY-YASDVWSFGVTLYELLT 1096
L + Y A D+W+ G + ELLT
Sbjct 169 VLLQSSIYDSAVDMWAMGAIMAELLT 194
>sp|Q7L7X3|TAOK1_HUMAN Serine/threonine-protein kinase TAO1 OS=Homo
sapiens OX=9606 GN=TAOK1 PE=1 SV=1
Length=1001
Score = 94.7 bits (234), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 78/239 (33%), Positives = 115/239 (48%), Gaps = 32/239 (13%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956
+R++G G FG V Y + T E+VA+K + + G Q W+ +E+ L+ + H
Sbjct 31 LREIGHGSFGAV----YFARDVRTNEVVAIKKM-SYSGKQSTEKWQDIIKEVKFLQRIKH 85
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014
+ I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL
Sbjct 86 PNSIEYKGCY--LREHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQGLAYL 142
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071
H+ IHRD+ A N+LL VK+ DFG A + + +P +W APE
Sbjct 143 HSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFV------GTP-YWMAPEVIL 195
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP----TKFLELIGIAQGQMTVLRLTE 1126
+ E ++ DVWS G+T EL + + PP L IAQ + L+ E
Sbjct 196 AMDEGQYDGKVDVWSLGITCIEL-----AERKPPLFNMNAMSALYHIAQNESPTLQSNE 249
Score = 34.7 bits (78), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 37/89 (42%), Gaps = 8/89 (9%)
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780
L+YL + ++H ++ NILL G +KL+D G A V W+A
Sbjct 138 GLAYLHSHTMIHRDIKAGNILLTEPGQ-------VKLADFGSASMASPANSFVGTPYWMA 190
Query 781 PEC-LPGGANSLSTAMDKWGFGATLLEIC 808
PE L +D W G T +E+
Sbjct 191 PEVILAMDEGQYDGKVDVWSLGITCIELA 219
>sp|Q00526|CDK3_HUMAN Cyclin-dependent kinase 3 OS=Homo sapiens
OX=9606 GN=CDK3 PE=1 SV=1
Length=305
Score = 90.5 bits (223), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 64/205 (31%), Positives = 104/205 (51%), Gaps = 15/205 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955
+K+ +GEG +G V Y N TG++VA+K ++ D + S +EI +L+ L
Sbjct 4 FQKVEKIGEGTYGVV----YKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELK 59
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013
H +I++ + E+ L LV E++ L D P + L + + Q+ +G+++
Sbjct 60 HPNIVRLLDVVHN--ERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSF 117
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072
H+ IHRDL +N+L++ +K+ DFGLA+A Y + WY APE
Sbjct 118 CHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTY----THEVVTLWYRAPEI 173
Query 1073 LKEYKFY-YASDVWSFGVTLYELLT 1096
L KFY A D+WS G E++T
Sbjct 174 LLGSKFYTTAVDIWSIGCIFAEMVT 198
Score = 38.1 bits (87), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 58/268 (22%), Positives = 106/268 (40%), Gaps = 43/268 (16%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
R+ GQ + + LD + SL+ ++ H ++ + V + +V E+
Sbjct 23 NRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEF 82
Query 690 VEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ L ++ G +P+ QL +S+ + ++H ++ +N+L+ LG
Sbjct 83 LSQD-LKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGA- 140
Query 749 EGTSPFIKLSDPGV----GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
IKL+D G+ G+ + V + + APE L G+ +TA+D W G
Sbjct 141 ------IKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILL-GSKFYTTAVDIWSIGCIF 193
Query 805 LEIC-----FDGEA--------------------PLQSRSPSEKEHFYQRQHRLPEPSCP 839
E+ F G++ P ++ P K F + + E P
Sbjct 194 AEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWTRKGLEEIVP 253
Query 840 QLA----TLTSQCLTYEPTQRPSFRTIL 863
L L Q L Y+P+QR + +T L
Sbjct 254 NLEPEGRDLLMQLLQYDPSQRITAKTAL 281
>sp|Q8BYC6|TAOK3_MOUSE Serine/threonine-protein kinase TAO3 OS=Mus
musculus OX=10090 GN=Taok3 PE=1 SV=2
Length=898
Score = 94.7 bits (234), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 72/203 (35%), Positives = 102/203 (50%), Gaps = 23/203 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956
+ ++G G FG V Y TN T E+VAVK + + G Q W+ +E+ L+ L H
Sbjct 27 LHEIGHGSFGAV----YFATNAHTNEVVAVKKM-SYSGKQTHEKWQDILKEVKFLQQLKH 81
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014
+ I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL
Sbjct 82 PNTIEYKGCY--LKEHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQGLAYL 138
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071
H IHRD+ A N+LL VK+ DFG A + + +P +W APE
Sbjct 139 HFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFV------GTP-YWMAPEVIL 191
Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094
+ E ++ D+WS G+T EL
Sbjct 192 AMDEGQYDGKVDIWSLGITCIEL 214
>sp|Q802A6|STK4_SQUAC Serine/threonine-protein kinase 3/4 OS=Squalus
acanthias OX=7797 GN=STK4 PE=2 SV=1
Length=491
Score = 93.2 bits (230), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 64/229 (28%), Positives = 108/229 (47%), Gaps = 18/229 (8%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
R PH + ++ DS P + + LGEG +G V + + +G++V
Sbjct 7 RQHPHPRRSLKKLSEDSLTKQP----EEVFDVLEKLGEGSYGSV----FKAIHKESGQVV 58
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K + + Q +EI I++ H++KY G + L +VMEY GS+
Sbjct 59 AIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTD--LWIVMEYCGAGSVS 113
Query 988 DYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
D + + L + + Q +G+ YLH IHRD+ A N+LL+N+ K+ DFG+A
Sbjct 114 DLIRIRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNNEGHAKLADFGVA 173
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
+ + R FW APE ++E + +D+WS G++ E+
Sbjct 174 GQLTDT---MAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGISAIEM 219
Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 51/214 (24%), Positives = 81/214 (38%), Gaps = 20/214 (9%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q H+ +G + + +V EY G + +R + + Q
Sbjct 77 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDLIRIRNKTLTEDEIATILQSTL 136
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL +H ++ NILL G A KL+D GV +++ V
Sbjct 137 KGLEYLHFMRKIHRDIKAGNILLNNEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 189
Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830
P W+APE + G N ++ D W G + +E+ +G+ P P
Sbjct 190 PFWMAPEVIQEIGYNCVA---DIWSLGISAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 245
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R PE + QCL P QR + +L+
Sbjct 246 FRKPELWTDEFTDFVKQCLVKNPEQRAAATQLLQ 279
>sp|Q91ZR4|NEK8_MOUSE Serine/threonine-protein kinase Nek8 OS=Mus
musculus OX=10090 GN=Nek8 PE=1 SV=1
Length=698
Score = 94.0 bits (232), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 64/203 (32%), Positives = 108/203 (53%), Gaps = 17/203 (8%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYH 956
++IR +G G FG V L C + ++V +K + + + R + E +L+ L H
Sbjct 5 ERIRVVGRGAFGIVHL-CLRKADQ---KLVILKQIPVEQMTKEERQAAQNECQVLKLLNH 60
Query 957 EHIIKY-KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMA 1012
++I+Y + ED K+L + MEY P G+L +++ + L + +L F QI +
Sbjct 61 PNVIEYYENFLED---KALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALH 117
Query 1013 YLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
++H +HRDL +N+LLD R+ VKIGDFG++K + + Y V +P + +PE
Sbjct 118 HVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVV---GTPCY-ISPE 173
Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094
+ + SD+W+ G LYEL
Sbjct 174 LCEGKPYNQKSDIWALGCVLYEL 196
>sp|B7ZR30|STK10_XENLA Serine/threonine-protein kinase 10-A OS=Xenopus
laevis OX=8355 GN=stk10-a PE=1 SV=1
Length=950
Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 68/203 (33%), Positives = 106/203 (52%), Gaps = 19/203 (9%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I +LG+G FGKV Y N TG + A K ++ + + EI+IL T H I
Sbjct 39 IGELGDGAFGKV----YKAKNRETGILAAAKVIETK-NEEELEDYMVEIEILATCNHHFI 93
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQ 1017
+K G +G+ L +++E+ P G++ + GL + + +Q+ E +AYLH+
Sbjct 94 VKLLGAFYWEGK--LWIMIEFCPGGAVDAVMLELDRGLKEPEIKTICRQMLEALAYLHSM 151
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVFWYAPEC---- 1072
IHRDL A NVLL D +K+ DFG+ AK V + + R+ +W APE
Sbjct 152 KIIHRDLKAGNVLLTLDGDIKLADFGVSAKNV----KTLQRRDSFIGTPYWMAPEVVMCE 207
Query 1073 -LKEYKFYYASDVWSFGVTLYEL 1094
+K+ + Y +D+WS G+TL E+
Sbjct 208 TMKDAPYDYKADIWSLGITLIEM 230
Score = 40.8 bits (94), Expect = 0.096, Method: Compositional matrix adjust.
Identities = 40/133 (30%), Positives = 60/133 (45%), Gaps = 17/133 (13%)
Query 684 IMVTEYVEHGPLD-VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
IM+ E+ G +D V L +RG K + +Q+ AL+YL + ++H ++ N+LL
Sbjct 108 IMI-EFCPGGAVDAVMLELDRGLKEPEIK-TICRQMLEALAYLHSMKIIHRDLKAGNVLL 165
Query 743 ARLGLAEGTSPFIKLSDPGV---GLGALSREERVERIP-WLAPE---CLPGGANSLSTAM 795
G IKL+D GV + L R + P W+APE C
Sbjct 166 TLDG-------DIKLADFGVSAKNVKTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKA 218
Query 796 DKWGFGATLLEIC 808
D W G TL+E+
Sbjct 219 DIWSLGITLIEMA 231
>sp|P24941|CDK2_HUMAN Cyclin-dependent kinase 2 OS=Homo sapiens
OX=9606 GN=CDK2 PE=1 SV=2
Length=298
Score = 90.1 bits (222), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 65/205 (32%), Positives = 102/205 (50%), Gaps = 15/205 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955
+K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ L
Sbjct 4 FQKVEKIGEGTYGVV----YKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYV--PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013
H +I+K E L LV E++ L D I L + + Q+ +G+A+
Sbjct 60 HPNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAF 117
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072
H+ +HRDL +N+L++ + +K+ DFGLA+A Y + WY APE
Sbjct 118 CHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTY----THEVVTLWYRAPEI 173
Query 1073 LKEYKFY-YASDVWSFGVTLYELLT 1096
L K+Y A D+WS G E++T
Sbjct 174 LLGCKYYSTAVDIWSLGCIFAEMVT 198
Score = 35.8 bits (81), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 65/321 (20%), Positives = 122/321 (38%), Gaps = 70/321 (22%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-LDPSHH 649
++ +G+GT VY+ R ++ G E+ + K+ LD
Sbjct 6 KVEKIGEGTYGVVYKARNKLTG-----------------------EVVALKKIRLDTETE 42
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
+ SL+ +++H ++ + V + +V E++ +P+
Sbjct 43 GVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLP 102
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLG 765
QL L++ + ++H ++ +N+L+ T IKL+D G+ G+
Sbjct 103 LIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI-------NTEGAIKLADFGLARAFGVP 155
Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQS--- 817
+ V + + APE L G STA+D W G E+ F G++ +
Sbjct 156 VRTYTHEVVTLWYRAPEIL-LGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFR 214
Query 818 ---RSPSEKEHFYQRQHRLPE--PSCPQLA----------------TLTSQCLTYEPTQR 856
+ E + +P+ PS P+ A +L SQ L Y+P +R
Sbjct 215 IFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKR 274
Query 857 PSFRTIL-----RDLTRLQPH 872
S + L +D+T+ PH
Sbjct 275 ISAKAALAHPFFQDVTKPVPH 295
>sp|Q03141|MARK3_MOUSE MAP/microtubule affinity-regulating kinase
3 OS=Mus musculus OX=10090 GN=Mark3 PE=1 SV=2
Length=753
Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 72/211 (34%), Positives = 103/211 (49%), Gaps = 16/211 (8%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQE 947
P + + R LK I G+G+F KV L + T G VA+K + K P +E
Sbjct 51 PHIGNYRLLKTI---GKGNFAKVKLARHILT----GREVAIKIIDKTQLNPTSLQKLFRE 103
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQ 1006
+ I++ L H +I+K E EK+L L+MEY G + DYL H + + +Q
Sbjct 104 VRIMKILNHPNIVKLFEVIET--EKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 161
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I + Y H + +HRDL A N+LLD D +KI DFG + G + G P
Sbjct 162 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGSKLDTF--CGSPP-- 217
Query 1067 WYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096
+ APE + K+ DVWS GV LY L++
Sbjct 218 YAAPELFQGKKYDGPEVDVWSLGVILYTLVS 248
Score = 40.8 bits (94), Expect = 0.095, Method: Compositional matrix adjust.
Identities = 49/236 (21%), Positives = 93/236 (39%), Gaps = 22/236 (9%)
Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K++D + + + +M ++H ++ + V ++ EY G +
Sbjct 82 VAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVF 141
Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+L H M K A+ Q+ SA+ Y K +VH ++ N+LL
Sbjct 142 DYLV---AHGRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLL-------DADMN 191
Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
IK++D G + +++ P+ APE G +D W G L +
Sbjct 192 IKIADFGFS-NEFTVGSKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLV-S 248
Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
G P ++ E +E + ++R+P L + L P +R + I++D
Sbjct 249 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMKD 304
>sp|Q95KV0|IKKB_BOVIN Inhibitor of nuclear factor kappa-B kinase
subunit beta OS=Bos taurus OX=9913 GN=IKBKB PE=2 SV=1
Length=756
Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 69/207 (33%), Positives = 100/207 (48%), Gaps = 23/207 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + N TGE +A+K + + P++R W EI I+R L H +++
Sbjct 21 LGTGGFGNVIRW----HNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLNHPNVVAA 76
Query 963 KGCCEDQGEKSLQ------LVMEYVPLGSLRDYLPR--HSIGLAQ--LLLFAQQICEGMA 1012
+ E G +SL L MEY G LR YL + + GL + +L I +
Sbjct 77 RDVPE--GMQSLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALR 134
Query 1013 YLHAQHYIHRDLAARNVLLDN--DRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH IHRDL N++L RL+ KI D G AK + +G + + + A
Sbjct 135 YLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGS----LCTSFVGTLQYLA 190
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096
PE L++ K+ D WSFG +E +T
Sbjct 191 PELLEQQKYTVTVDYWSFGTLAFECIT 217
>sp|Q9HFW2|CLA4_EREGS Serine/threonine-protein kinase CLA4 OS=Eremothecium
gossypii (strain ATCC 10895 / CBS 109.51 / FGSC
9923 / NRRL Y-1056) OX=284811 GN=CLA4 PE=3 SV=1
Length=793
Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 69/232 (30%), Positives = 108/232 (47%), Gaps = 33/232 (14%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLY------CYDPT--------NDGTGEMVAVKAL 932
+DP+ F + I G+G G V L YD ND G+ VA+K +
Sbjct 492 TDPSPF----FQMIEKAGQGASGSVYLAQRLKIPPYDENSGVSQHELNDNIGDKVAIKQM 547
Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992
P+ + EI +++ H++I+ + + E L +VMEY+ GSL D +
Sbjct 548 ILSKQPR-KELIVNEILVMKDSQHKNIVNFLEAYL-KTEDDLWVVMEYMEGGSLTDVI-E 604
Query 993 HSIGL---------AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
+SIG Q+ ++ C+G+ +LH +H IHRD+ + NVLLD VKI DFG
Sbjct 605 NSIGSDASESPMTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTHGRVKITDFG 664
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+ + R +W APE +K+ ++ DVWS G+ E+L
Sbjct 665 FCAKLTDKRSK---RATMVGTPYWMAPEVVKQREYDEKVDVWSLGIMTIEML 713
Score = 39.7 bits (91), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 51/214 (24%), Positives = 89/214 (42%), Gaps = 33/214 (15%)
Query 685 MVTEYVEHGPLDVWLRRERG----HVPMAWKMV--VAQQLASALSYLENKNLVHGNVCGR 738
+V EY+E G L + G PM + + ++ L +L +K+++H ++
Sbjct 589 VVMEYMEGGSLTDVIENSIGSDASESPMTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSD 648
Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLS 792
N+LL G +K++D G A ++R +R W+APE +
Sbjct 649 NVLLDTHGR-------VKITD--FGFCAKLTDKRSKRATMVGTPYWMAPEVV--KQREYD 697
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLT-----SQ 847
+D W G +E+ +GE P + P K + + P+ P+L +L S
Sbjct 698 EKVDVWSLGIMTIEM-LEGEPPYLNEEPL-KALYLIATNGTPKLKHPELLSLEIKRFLSV 755
Query 848 CLTYEPTQRPSFRTILRDL---TRLQPHNLADVL 878
CL + R S +L T +P LA++L
Sbjct 756 CLCVDVRYRASTEELLHHSFFETSCEPEELANLL 789
>sp|O88664|TAOK1_RAT Serine/threonine-protein kinase TAO1 OS=Rattus
norvegicus OX=10116 GN=Taok1 PE=1 SV=1
Length=1001
Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 78/239 (33%), Positives = 115/239 (48%), Gaps = 32/239 (13%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956
+R++G G FG V Y + T E+VA+K + + G Q W+ +E+ L+ + H
Sbjct 31 LREIGHGSFGAV----YFARDVRTNEVVAIKKM-SYSGKQSTEKWQDIIKEVKFLQRIKH 85
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014
+ I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL
Sbjct 86 PNSIEYKGCY--LREHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQGLAYL 142
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071
H+ IHRD+ A N+LL VK+ DFG A + + +P +W APE
Sbjct 143 HSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFV------GTP-YWMAPEVIL 195
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP----TKFLELIGIAQGQMTVLRLTE 1126
+ E ++ DVWS G+T EL + + PP L IAQ + L+ E
Sbjct 196 AMDEGQYDGKVDVWSLGITCIEL-----AERKPPLFNMNAMSALYHIAQNESPTLQSNE 249
Score = 34.7 bits (78), Expect = 7.6, Method: Compositional matrix adjust.
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781
L+YL + ++H ++ NILL G +KL+D G A V W+AP
Sbjct 139 LAYLHSHTMIHRDIKAGNILLTEPGQ-------VKLADFGSASMASPANSFVGTPYWMAP 191
Query 782 EC-LPGGANSLSTAMDKWGFGATLLEIC 808
E L +D W G T +E+
Sbjct 192 EVILAMDEGQYDGKVDVWSLGITCIELA 219
>sp|Q38997|KIN10_ARATH SNF1-related protein kinase catalytic subunit
alpha KIN10 OS=Arabidopsis thaliana OX=3702 GN=KIN10
PE=1 SV=3
Length=512
Score = 93.2 bits (230), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 74/200 (37%), Positives = 100/200 (50%), Gaps = 16/200 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEH 958
R LG G FG+V + + TG VA+K L + + ++EI ILR H H
Sbjct 23 RTLGIGSFGRVKI----AEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPH 78
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
II+ E + + LVMEYV G L DY+ + + + F QQI G+ Y H
Sbjct 79 IIRLYEVIETPTD--IYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRN 136
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL N+LLD+ VKI DFGL+ + +GH ++ SP + APE + K
Sbjct 137 MVVHRDLKPENLLLDSKCNVKIADFGLSNIMRDGH---FLKTSCGSPNY-AAPEVISG-K 191
Query 1078 FYYA--SDVWSFGVTLYELL 1095
Y DVWS GV LY LL
Sbjct 192 LYAGPEVDVWSCGVILYALL 211
Score = 34.3 bits (77), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 57/263 (22%), Positives = 99/263 (38%), Gaps = 20/263 (8%)
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726
H H+ ++ V + +V EYV G L ++ E+G + QQ+ S + Y
Sbjct 76 HPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIV-EKGRLQEDEARNFFQQIISGVEYCH 134
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-----WLAP 781
+VH ++ N+LL + +K++D GL + R+ + + AP
Sbjct 135 RNMVVHRDLKPENLLL-------DSKCNVKIAD--FGLSNIMRDGHFLKTSCGSPNYAAP 185
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQ 840
E + G + +D W G L + G P + P+ + + LP P
Sbjct 186 EVISGKLYA-GPEVDVWSCGVILYALLC-GTLPFDDENIPNLFKKIKGGIYTLPSHLSPG 243
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
L + L +P +R + I R Q H L L V P + L+++
Sbjct 244 ARDLIPRMLVVDPMKRVTIPEI-RQHPWFQAH-LPRYLAVPPPDTVQQAKKIDEEILQEV 301
Query 901 RDLGEGHFGKVSLYCYDPTNDGT 923
++G + NDGT
Sbjct 302 INMGFDRNHLIESLRNRTQNDGT 324
>sp|Q5F2E8|TAOK1_MOUSE Serine/threonine-protein kinase TAO1 OS=Mus
musculus OX=10090 GN=Taok1 PE=1 SV=1
Length=1001
Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 78/239 (33%), Positives = 115/239 (48%), Gaps = 32/239 (13%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956
+R++G G FG V Y + T E+VA+K + + G Q W+ +E+ L+ + H
Sbjct 31 LREIGHGSFGAV----YFARDVRTNEVVAIKKM-SYSGKQSTEKWQDIIKEVKFLQRIKH 85
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014
+ I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL
Sbjct 86 PNSIEYKGCY--LREHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQGLAYL 142
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071
H+ IHRD+ A N+LL VK+ DFG A + + +P +W APE
Sbjct 143 HSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFV------GTP-YWMAPEVIL 195
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP----TKFLELIGIAQGQMTVLRLTE 1126
+ E ++ DVWS G+T EL + + PP L IAQ + L+ E
Sbjct 196 AMDEGQYDGKVDVWSLGITCIEL-----AERKPPLFNMNAMSALYHIAQNESPTLQSNE 249
Score = 34.7 bits (78), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781
L+YL + ++H ++ NILL G +KL+D G A V W+AP
Sbjct 139 LAYLHSHTMIHRDIKAGNILLTEPGQ-------VKLADFGSASMASPANSFVGTPYWMAP 191
Query 782 EC-LPGGANSLSTAMDKWGFGATLLEIC 808
E L +D W G T +E+
Sbjct 192 EVILAMDEGQYDGKVDVWSLGITCIELA 219
>sp|Q5RDG7|MYLK3_PONAB Myosin light chain kinase 3 OS=Pongo abelii
OX=9601 GN=MYLK3 PE=2 SV=3
Length=819
Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 72/202 (36%), Positives = 101/202 (50%), Gaps = 23/202 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG+V + T TG +A K +K + R K EI+I+ L H ++I+
Sbjct 521 LGGGRFGQV----HRCTEKSTGLPLAAKIIKVKSA-KDREDVKNEINIMNQLSHVNLIQL 575
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020
E + S LVMEYV G L D + L +L +LF +QICEG+ YLH + +
Sbjct 576 YDAFESK--HSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYIL 633
Query 1021 HRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVRE----DGDSPVFWYAPECLK 1074
H DL N+L N +KI DFGLA+ Y+ RE + +P F APE +
Sbjct 634 HLDLKPENILCVNQTGHQIKIIDFGLAR-------RYKPREKLKVNFGTPEF-LAPEVVN 685
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ +D+WS GV Y LL+
Sbjct 686 YEFVSFPTDMWSVGVITYMLLS 707
Score = 34.3 bits (77), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 39/170 (23%), Positives = 72/170 (42%), Gaps = 11/170 (6%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
++M+Q+SH +L ++ +V EYV+ G L + E+ H+ ++ +Q+
Sbjct 562 NIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQIC 621
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE---RVERI 776
+ YL ++H ++ NIL T IK+ D G+ RE+
Sbjct 622 EGVHYLHQHYILHLDLKPENILCVNQ-----TGHQIKIIDFGLARRYKPREKLKVNFGTP 676
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+LAPE + +S D W G + + G +P + +E +F
Sbjct 677 EFLAPEVV--NYEFVSFPTDMWSVG-VITYMLLSGLSPFLGETDAETMNF 723
>sp|Q9FLJ8|Y5613_ARATH Probable receptor-like protein kinase At5g61350
OS=Arabidopsis thaliana OX=3702 GN=At5g61350 PE=2 SV=1
Length=842
Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 72/206 (35%), Positives = 101/206 (49%), Gaps = 26/206 (13%)
Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963
G G FGKV Y DG G VA+K + Q + ++ EI +L L H H++
Sbjct 532 GVGGFGKV----YIGEIDG-GTQVAIKR-GSQSSEQGINEFQTEIQMLSKLRHRHLVSLI 585
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYL---------PRHSIGLAQLLLFAQQICEGMAYL 1014
G C++ K + LV EY+ G LRD+L P ++ Q L G+ YL
Sbjct 586 GFCDEN--KEMILVYEYMSNGPLRDHLYGSKENDPNPIPTLSWKQRLEICIGSARGLHYL 643
Query 1015 H---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP--EGHEYYRVREDGDSPVFWYA 1069
H AQ IHRD+ N+LLD + + K+ DFGL+K P EGH V+ +
Sbjct 644 HTGAAQGIIHRDVKTTNILLDENLVAKVSDFGLSKDAPMDEGHVSTAVK----GSFGYLD 699
Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095
PE + + SDV+SFGV L+E+L
Sbjct 700 PEYFRRQQLTDKSDVYSFGVVLFEVL 725
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 47/168 (28%), Positives = 72/168 (43%), Gaps = 24/168 (14%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP-----MA 709
F ++S++ H HL + G C E I+V EY+ +GPL L + + P ++
Sbjct 566 FQTEIQMLSKLRHRHLVSLIGFCDENKEMILVYEYMSNGPLRDHLYGSKENDPNPIPTLS 625
Query 710 WKMVVAQQLASA--LSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
WK + + SA L YL + ++H +V NILL +A K+SD G+
Sbjct 626 WKQRLEICIGSARGLHYLHTGAAQGIIHRDVKTTNILLDENLVA-------KVSDFGLSK 678
Query 765 GALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
A E V +L PE L+ D + FG L E+
Sbjct 679 DAPMDEGHVSTAVKGSFGYLDPEYFR--RQQLTDKSDVYSFGVVLFEV 724
>sp|Q94CG0|CIPKL_ARATH CBL-interacting serine/threonine-protein
kinase 21 OS=Arabidopsis thaliana OX=3702 GN=CIPK21 PE=1 SV=1
Length=416
Score = 92.0 bits (227), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 74/199 (37%), Positives = 106/199 (53%), Gaps = 15/199 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEH 958
R +GEG+F KV L YD TN G VAVK + Q S K+EI ++ L H +
Sbjct 16 RTIGEGNFAKVKL-GYDTTN---GTYVAVKIIDKALVIQKGLESQVKREIRTMKLLNHPN 71
Query 959 IIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
I++ E G K+ + +VMEYV G L D L R + + QQ+ + + Y H +
Sbjct 72 IVQIH---EVIGTKTKICIVMEYVSGGQLSDRLGRQKMKESDARKLFQQLIDAVDYCHNR 128
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
HRDL +N+LLD+ +K+ DFGL+ AVP+ + + SP + APE +
Sbjct 129 GVYHRDLKPQNLLLDSKGNLKVSDFGLS-AVPKSGDM--LSTACGSPC-YIAPELIMNKG 184
Query 1078 FYYAS-DVWSFGVTLYELL 1095
+ A+ DVWS GV L+ELL
Sbjct 185 YSGAAVDVWSCGVILFELL 203
Score = 43.5 bits (101), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 41/151 (27%), Positives = 68/151 (45%), Gaps = 17/151 (11%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA 721
M ++H ++ +H V + +V EYV G L L R++ A K+ QQL A
Sbjct 64 MKLLNHPNIVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQKMKESDARKLF--QQLIDA 121
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---- 777
+ Y N+ + H ++ +N+LL G +K+SD GL A+ + +
Sbjct 122 VDYCHNRGVYHRDLKPQNLLLDSKG-------NLKVSD--FGLSAVPKSGDMLSTACGSP 172
Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
++APE + S A+D W G L E+
Sbjct 173 CYIAPELIMNKGYS-GAAVDVWSCGVILFEL 202
>sp|O88351|IKKB_MOUSE Inhibitor of nuclear factor kappa-B kinase
subunit beta OS=Mus musculus OX=10090 GN=Ikbkb PE=1 SV=1
Length=757
Score = 94.0 bits (232), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 68/207 (33%), Positives = 101/207 (49%), Gaps = 23/207 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + N TGE +A+K + + P++R+ W EI I+R L H +++
Sbjct 21 LGTGGFGNVIRW----HNQATGEQIAIKQCRQELSPKNRNRWCLEIQIMRRLNHPNVVAA 76
Query 963 KGCCEDQGEKSLQ------LVMEYVPLGSLRDYLPR--HSIGLAQ--LLLFAQQICEGMA 1012
+ E G ++L L MEY G LR YL + + GL + +L I +
Sbjct 77 RDVPE--GMQNLAPNDLPLLAMEYCQGGDLRRYLNQFENCCGLREGAVLTLLSDIASALR 134
Query 1013 YLHAQHYIHRDLAARNVLLDN--DRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH IHRDL N++L RL+ KI D G AK + +G + + + A
Sbjct 135 YLHENRIIHRDLKPENIVLQQGEKRLIHKIIDLGYAKELDQGS----LCTSFVGTLQYLA 190
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096
PE L++ K+ D WSFG +E +T
Sbjct 191 PELLEQQKYTVTVDYWSFGTLAFECIT 217
>sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo
sapiens OX=9606 GN=MARK2 PE=1 SV=2
Length=788
Score = 94.0 bits (232), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 73/211 (35%), Positives = 104/211 (49%), Gaps = 16/211 (8%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQE 947
P + + R LK I G+G+F KV L + T G+ VAVK + K +E
Sbjct 48 PHIGNYRLLKTI---GKGNFAKVKLARHILT----GKEVAVKIIDKTQLNSSSLQKLFRE 100
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQ 1006
+ I++ L H +I+K E EK+L LVMEY G + DYL H + + +Q
Sbjct 101 VRIMKVLNHPNIVKLFEVIET--EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 158
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I + Y H + +HRDL A N+LLD D +KI DFG + G++ G P
Sbjct 159 IVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTF--CGSPP-- 214
Query 1067 WYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096
+ APE + K+ DVWS GV LY L++
Sbjct 215 YAAPELFQGKKYDGPEVDVWSLGVILYTLVS 245
Score = 40.4 bits (93), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 22/236 (9%)
Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K++D + + + + +M ++H ++ + V +V EY G +
Sbjct 79 VAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVF 138
Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+L H M K A+ Q+ SA+ Y K +VH ++ N+LL
Sbjct 139 DYLV---AHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLL-------DADMN 188
Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
IK++D G + +++ P+ APE G +D W G L +
Sbjct 189 IKIADFGFS-NEFTFGNKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLV-S 245
Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
G P ++ E +E + ++R+P L + L P++R + I++D
Sbjct 246 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKD 301
>sp|Q6NKZ9|Y4345_ARATH Probable receptor-like serine/threonine-protein
kinase At4g34500 OS=Arabidopsis thaliana OX=3702 GN=At4g34500
PE=2 SV=1
Length=437
Score = 92.4 bits (228), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 78/278 (28%), Positives = 127/278 (46%), Gaps = 19/278 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG +G V Y D ++ G + AVK L + G Q +K E++ + + H++++
Sbjct 151 IGEGGYGVV--YRADFSD---GSVAAVKNLLNNKG-QAEKEFKVEVEAIGKVRHKNLVGL 204
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
G C D + LV EY+ G+L +L P + + A +G+AYLH
Sbjct 205 MGYCADSAQSQRMLVYEYIDNGNLEQWLHGDVGPVSPLTWDIRMKIAIGTAKGLAYLHEG 264
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECL 1073
+HRD+ + N+LLD K+ DFGLAK + Y R G F Y +PE
Sbjct 265 LEPKVVHRDVKSSNILLDKKWNAKVSDFGLAKLLGSETSYVTTRVMG---TFGYVSPEYA 321
Query 1074 KEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
SDV+SFGV L E++T S P + L+ +G + R E+++
Sbjct 322 STGMLNECSDVYSFGVLLMEIITGRSPVDYSRPPGEMNLVDWFKGMVASRRGEEVIDPKI 381
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ P + + C + ++S RP +I +L+
Sbjct 382 KTSPPPRALKRALLVCLRCIDLDSSKRPKMGQIIHMLE 419
Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 63/233 (27%), Positives = 104/233 (45%), Gaps = 41/233 (18%)
Query 662 MSQVSHTHLAFVHGVCVRGPEN--IMVTEYVEHGPLDVWLRRERGHV-PMAW--KMVVAQ 716
+ +V H +L + G C ++ ++V EY+++G L+ WL + G V P+ W +M +A
Sbjct 193 IGKVRHKNLVGLMGYCADSAQSQRMLVYEYIDNGNLEQWLHGDVGPVSPLTWDIRMKIAI 252
Query 717 QLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSR-- 769
A L+YL +VH +V NILL + A K+SD G+ LG+ +
Sbjct 253 GTAKGLAYLHEGLEPKVVHRDVKSSNILLDKKWNA-------KVSDFGLAKLLGSETSYV 305
Query 770 EERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ-SRSPSE----- 822
RV +++PE G L+ D + FG L+EI G +P+ SR P E
Sbjct 306 TTRVMGTFGYVSPEYASTGM--LNECSDVYSFGVLLMEI-ITGRSPVDYSRPPGEMNLVD 362
Query 823 -----------KEHFYQRQHRLPEPSCPQLATLTS-QCLTYEPTQRPSFRTIL 863
+E + P P + A L +C+ + ++RP I+
Sbjct 363 WFKGMVASRRGEEVIDPKIKTSPPPRALKRALLVCLRCIDLDSSKRPKMGQII 415
>sp|P0C0K7|EPHB6_RAT Ephrin type-B receptor 6 OS=Rattus norvegicus
OX=10116 GN=Ephb6 PE=3 SV=3
Length=1013
Score = 94.4 bits (233), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 73/290 (25%), Positives = 132/290 (46%), Gaps = 36/290 (12%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DPT Y+K +G G FG+V P + VA++AL A + +
Sbjct 658 DPT-----YIKIEEVIGAGSFGEVRRGRLQPRGRRE-QAVAIQALWAGGAESLKMTFLGR 711
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ- 1006
+L H +I++ +G + + ++ E + LG L +L + + L L A Q
Sbjct 712 AALLGQFQHPNILRLEGVVTR--SRPVMVLTELMELGPLDSFLRQREGQFSSLQLVAMQR 769
Query 1007 -ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
+ M YL + ++HR L+AR+VL+++ + K+ G + P+G S +
Sbjct 770 GVAAAMQYLSSFAFVHRALSARSVLVNSHLVCKVARLGHS---PQG---------SSSLL 817
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
W APE + K+ +SDVWSFG+ ++E++++ + M+ +
Sbjct 818 RWAAPEVITHGKYTTSSDVWSFGILMWEVMSYGER--------------PYWDMSDQEVL 863
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+E+ RLP P CP ++ LM + W+ + + RP F+ L+ + K
Sbjct 864 NAIEQEFRLPPPPGCPTGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRK 913
Score = 74.7 bits (182), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 61/250 (24%), Positives = 109/250 (44%), Gaps = 34/250 (14%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
R R ++ + + + + F A+L+ Q H ++ + GV R +++TE +
Sbjct 684 RGRREQAVAIQALWAGGAESLKMTFLGRAALLGQFQHPNILRLEGVVTRSRPVMVLTELM 743
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL--------L 742
E GPLD +LR+ G + + + +A+A+ YL + VH + R++L +
Sbjct 744 ELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRALSARSVLVNSHLVCKV 803
Query 743 ARLGLA-EGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
ARLG + +G+S ++ W APE + G +T+ D W FG
Sbjct 804 ARLGHSPQGSSSLLR---------------------WAAPEVITHG--KYTTSSDVWSFG 840
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSF 859
+ E+ GE P S E + +++ RL P P CP L L + +RP F
Sbjct 841 ILMWEVMSYGERPYWDMSDQEVLNAIEQEFRLPPPPGCPTGLHLLMLDTWQKDRARRPHF 900
Query 860 RTILRDLTRL 869
++ ++
Sbjct 901 DQLVAAFDKM 910
>sp|Q3E8W4|ANX2_ARATH Receptor-like protein kinase ANXUR2 OS=Arabidopsis
thaliana OX=3702 GN=ANX2 PE=1 SV=1
Length=858
Score = 94.0 bits (232), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 79/276 (29%), Positives = 129/276 (47%), Gaps = 26/276 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FGKV Y DG G VA+K + Q + ++ EI++L L H+H++
Sbjct 527 IGVGGFGKV----YKGVIDG-GTKVAIKKSNPNS-EQGLNEFETEIELLSRLRHKHLVSL 580
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA--- 1016
G C++ GE + L+ +Y+ LG+LR++L R + + L A G+ YLH
Sbjct 581 IGYCDEGGE--MCLIYDYMSLGTLREHLYNTKRPQLTWKRRLEIAIGAARGLHYLHTGAK 638
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE---GHEYYRVREDGDSPVFWYAPECL 1073
IHRD+ N+LLD + + K+ DFGL+K P GH V+ + PE
Sbjct 639 YTIIHRDVKTTNILLDENWVAKVSDFGLSKTGPNMNGGHVTTVVK----GSFGYLDPEYF 694
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR---LTELLER 1130
+ + SDV+SFGV L+E+L C P+ E + + M R L ++++
Sbjct 695 RRQQLTEKSDVYSFGVVLFEVL--CARPALNPSLSKEQVSLGDWAMNCKRKGTLEDIIDP 752
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ +C + + C RPT +++
Sbjct 753 NLKGKINPECLKKFADTAEKCLSDSGLDRPTMGDVL 788
Score = 42.4 bits (98), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 42/175 (24%), Positives = 74/175 (42%), Gaps = 9/175 (5%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K +P+ F L+S++ H HL + G C G E ++ +Y+ G L
Sbjct 545 KVAIKKSNPNSEQGLNEFETEIELLSRLRHKHLVSLIGYCDEGGEMCLIYDYMSLGTLRE 604
Query 698 WLRRERGHVPMAWK--MVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752
L + + WK + +A A L YL ++H +V NILL +A+ +
Sbjct 605 HLYNTK-RPQLTWKRRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILLDENWVAKVSD 663
Query 753 PFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+ + P + G ++ + +L PE L+ D + FG L E+
Sbjct 664 FGLSKTGPNMNGGHVTTVVK-GSFGYLDPEYFR--RQQLTEKSDVYSFGVVLFEV 715
>sp|Q1PE89|PBL24_ARATH Probable serine/threonine-protein kinase
PBL24 OS=Arabidopsis thaliana OX=3702 GN=PBL24 PE=2 SV=1
Length=389
Score = 91.7 bits (226), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 77/219 (35%), Positives = 110/219 (50%), Gaps = 21/219 (10%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
A+ F + +L +GEG FG+V Y + TG++VAVK L + G Q +
Sbjct 65 ATATNSFRQEFL-----IGEGGFGRV----YKGKMEKTGQVVAVKQLDRN-GLQGNREFL 114
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL----- 1000
EI L L+H ++ G C D G++ L LV E++PLGSL D+L +G L
Sbjct 115 VEIFRLSLLHHPNLANLIGYCLD-GDQRL-LVHEFMPLGSLEDHLLDVVVGQQPLDWNSR 172
Query 1001 LLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ A +G+ YLH + I+RD + N+LL+ D K+ DFGLAK G + V
Sbjct 173 IRIALGAAKGLEYLHEKANPPVIYRDFKSSNILLNVDFDAKLSDFGLAKLGSVG-DTQNV 231
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+ APE K + SDV+SFGV L EL+T
Sbjct 232 SSRVVGTYGYCAPEYHKTGQLTVKSDVYSFGVVLLELIT 270
Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 69/283 (24%), Positives = 111/283 (39%), Gaps = 43/283 (15%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DV 697
V +K LD + F +S + H +LA + G C+ G + ++V E++ G L D
Sbjct 97 VAVKQLDRNGLQGNREFLVEIFRLSLLHHPNLANLIGYCLDGDQRLLVHEFMPLGSLEDH 156
Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTS 752
L G P+ W ++ +A A L YL K +++ + NILL
Sbjct 157 LLDVVVGQQPLDWNSRIRIALGAAKGLEYLHEKANPPVIYRDFKSSNILL-------NVD 209
Query 753 PFIKLSDPGVG-LGALSREERVE-RIPWLAPECLPG--GANSLSTAMDKWGFGATLLEIC 808
KLSD G+ LG++ + V R+ C P L+ D + FG LLE+
Sbjct 210 FDAKLSDFGLAKLGSVGDTQNVSSRVVGTYGYCAPEYHKTGQLTVKSDVYSFGVVLLEL- 268
Query 809 FDGEAPLQSRSPSEKEHFYQ-------------------RQHRLPEPSCPQLATLTSQCL 849
G+ + + P +++ Q PE S Q + + CL
Sbjct 269 ITGKRVIDTTRPCHEQNLVTWAQPIFREPNRFPELADPLLQGEFPEKSLNQAVAIAAMCL 328
Query 850 TYEPTQRPSFRTILRDLTRL-----QPHNLADVLTVNPDSPAS 887
EP RP ++ L+ + P L +NP SP +
Sbjct 329 QEEPIVRPLISDVVTALSFMSTETGSPSGLTGT-ALNPLSPKT 370
>sp|B4KPU0|PTK7_DROMO Tyrosine-protein kinase-like otk OS=Drosophila
mojavensis OX=7230 GN=otk PE=3 SV=1
Length=1045
Score = 94.4 bits (233), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 70/254 (28%), Positives = 120/254 (47%), Gaps = 30/254 (12%)
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
+V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY G
Sbjct 795 LVMVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPH--YMVLEYTDWGD 852
Query 986 LRDYLPRHS--------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031
L+ +L + + +QLL A QI GM ++ + HRDLA RN ++
Sbjct 853 LKQFLLATAGKVNTATATSSPPPLTTSQLLAVAYQIARGMDAIYRARFTHRDLATRNCVI 912
Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091
++ +VK+ L K EY++ R + PV W APEC++E ++ SD+++F V +
Sbjct 913 SSEFIVKVAYPALCKD-KYSREYHKHR-NTLLPVRWLAPECIQEDEYTTKSDIFAFAVVV 970
Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
+EL TK L ++ Q+ L LE PD + ++ +C
Sbjct 971 WELFNQA-------TK-LPHEDLSNEQVVQRSLANTLEWSVAEGTPDG----LKEILLSC 1018
Query 1152 WETEASFRPTFENL 1165
W T RP+F L
Sbjct 1019 WLTNPKERPSFSQL 1032
Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 62/258 (24%), Positives = 103/258 (40%), Gaps = 37/258 (14%)
Query 636 ELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+L V++K L+ + A F L+ +SH + + G+C + MV EY + G
Sbjct 793 DLLVMVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDWGD 852
Query 695 LDVWLRRERGHVPMAWK------------MVVAQQLASALSYLENKNLVHGNVCGRNILL 742
L +L G V A + VA Q+A + + H ++ RN ++
Sbjct 853 LKQFLLATAGKVNTATATSSPPPLTTSQLLAVAYQIARGMDAIYRARFTHRDLATRNCVI 912
Query 743 ARLGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMD 796
+S FI K++ P + SRE R + WLAPEC+ + +T D
Sbjct 913 --------SSEFIVKVAYPALCKDKYSREYHKHRNTLLPVRWLAPECIQ--EDEYTTKSD 962
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR------QHRLPEPSCPQLATLTSQCLT 850
+ F + E+ F+ L S E QR + + E + L + C
Sbjct 963 IFAFAVVVWEL-FNQATKLPHEDLS-NEQVVQRSLANTLEWSVAEGTPDGLKEILLSCWL 1020
Query 851 YEPTQRPSFRTILRDLTR 868
P +RPSF + L++
Sbjct 1021 TNPKERPSFSQLGAALSK 1038
>sp|Q05609|CTR1_ARATH Serine/threonine-protein kinase CTR1 OS=Arabidopsis
thaliana OX=3702 GN=CTR1 PE=1 SV=1
Length=821
Score = 94.0 bits (232), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 79/280 (28%), Positives = 130/280 (46%), Gaps = 42/280 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V + G VAVK L + D + + + +E+ I++ L H +I+
Sbjct 557 IGAGSFGTVHRAEW------HGSDVAVKILMEQDFHAERVNEFLREVAIMKRLRHPNIVL 610
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G +L +V EY+ GSL L R + + L A + +GM YLH +
Sbjct 611 FMGAVTQ--PPNLSIVTEYLSRGSLYRLLHKSGAREQLDERRRLSMAYDVAKGMNYLHNR 668
Query 1018 H--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ +HRDL + N+L+D VK+ DFGL++ + + + +P W APE L++
Sbjct 669 NPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRL--KASTFLSSKSAAGTPE-WMAPEVLRD 725
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSP-----PTKFLELIGIAQGQMTVLRLTELLER 1130
SDV+SFGV L+EL T Q P P + + +G +
Sbjct 726 EPSNEKSDVYSFGVILWELATL----QQPWGNLNPAQVVAAVGF---------------K 766
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+RL P +V +++ CW E RP+F ++ +L+
Sbjct 767 CKRLEIPRNLNPQVAAIIEGCWTNEPWKRPSFATIMDLLR 806
Score = 65.5 bits (158), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 63/246 (26%), Positives = 114/246 (46%), Gaps = 22/246 (9%)
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
G ++ V + + H + F ++M ++ H ++ G + P +VTEY+ G
Sbjct 572 GSDVAVKILMEQDFHAERVNEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRG 631
Query 694 PLDVWLRRE--RGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAE 749
L L + R + ++ +A +A ++YL N+N +VH ++ N+L+ +
Sbjct 632 SLYRLLHKSGAREQLDERRRLSMAYDVAKGMNYLHNRNPPIVHRDLKSPNLLVDK----- 686
Query 750 GTSPFIKLSDPGVG-LGA---LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+K+ D G+ L A LS + W+APE L ++ + D + FG L
Sbjct 687 --KYTVKVCDFGLSRLKASTFLSSKSAAGTPEWMAPEVLRDEPSNEKS--DVYSFGVILW 742
Query 806 EICFDGEAPLQSRSPSE---KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
E+ + P + +P++ F ++ +P PQ+A + C T EP +RPSF TI
Sbjct 743 ELA-TLQQPWGNLNPAQVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNEPWKRPSFATI 801
Query 863 LRDLTR 868
+ DL R
Sbjct 802 M-DLLR 806
>sp|C0LGE0|Y1765_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g07650 OS=Arabidopsis thaliana OX=3702
GN=At1g07650 PE=1 SV=1
Length=1014
Score = 94.4 bits (233), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 86/289 (30%), Positives = 132/289 (46%), Gaps = 38/289 (13%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R +GEG FG S+Y + + G+++AVK L A +R + EI ++ L H +++
Sbjct 682 RKIGEGGFG--SVYKGELSE---GKLIAVKQLSAKSRQGNRE-FVNEIGMISALQHPNLV 735
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSL------RDYLPRHSIGLAQLLLFAQQICEGMAYL 1014
K GCC + + L LV EY+ L +D R + + I +G+ +L
Sbjct 736 KLYGCCVEGNQ--LILVYEYLENNCLSRALFGKDESSRLKLDWSTRKKIFLGIAKGLTFL 793
Query 1015 HAQHYI---HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
H + I HRD+ A NVLLD D KI DFGLAK +G+ + R G + + APE
Sbjct 794 HEESRIKIVHRDIKASNVLLDKDLNAKISDFGLAKLNDDGNTHISTRIAG--TIGYMAPE 851
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQMTVLRLTELLER 1130
+DV+SFGV E+++ ++ PT+ F+ L+ A L ER
Sbjct 852 YAMRGYLTEKADVYSFGVVALEIVSGKSNTNFRPTEDFVYLLDWAY---------VLQER 902
Query 1131 GERLPRPDKCPCEVYH-----LMKN----CWETEASFRPTFENLIPILK 1170
G L D Y LM N C + RPT ++ +++
Sbjct 903 GSLLELVDPTLASDYSEEEAMLMLNVALMCTNASPTLRPTMSQVVSLIE 951
Score = 53.9 bits (128), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 78/328 (24%), Positives = 130/328 (40%), Gaps = 64/328 (20%)
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
+RG T L Q+ D ++T+ +G+G +VY+G L EGK+
Sbjct 656 LRGLDLQTGTFTLRQIK-AATDNFDVTR--KIGEGGFGSVYKGEL--------SEGKL-- 702
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
+ +K L F ++S + H +L ++G CV G +
Sbjct 703 ---------------IAVKQLSAKSRQGNREFVNEIGMISALQHPNLVKLYGCCVEGNQL 747
Query 684 IMVTEYVEHGPLDVWL--RRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVC 736
I+V EY+E+ L L + E + + W + + +A L++L ++ +VH ++
Sbjct 748 ILVYEYLENNCLSRALFGKDESSRLKLDWSTRKKIFLGIAKGLTFLHEESRIKIVHRDIK 807
Query 737 GRNILLARLGLAEGTSPF--IKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTA 794
N+LL + L S F KL+D G I ++APE G L+
Sbjct 808 ASNVLLDK-DLNAKISDFGLAKLNDDG---NTHISTRIAGTIGYMAPEYAMRGY--LTEK 861
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEK-------EHFYQRQHRLPEPSCPQLATLTSQ 847
D + FG LEI G++ R P+E + Q + L E P LA+ S+
Sbjct 862 ADVYSFGVVALEIV-SGKSNTNFR-PTEDFVYLLDWAYVLQERGSLLELVDPTLASDYSE 919
Query 848 ------------CLTYEPTQRPSFRTIL 863
C PT RP+ ++
Sbjct 920 EEAMLMLNVALMCTNASPTLRPTMSQVV 947
>sp|Q9LW83|CE101_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase CES101 OS=Arabidopsis thaliana OX=3702
GN=CES101 PE=2 SV=2
Length=850
Score = 94.0 bits (232), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 76/219 (35%), Positives = 105/219 (48%), Gaps = 24/219 (11%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG---TGEMVAVKALKADCGPQHRSGW 944
+ F Y LGEG FG P G GE VA+K L G Q +
Sbjct 518 ESVAFATDYFSDANKLGEGGFG--------PVYKGRLIDGEEVAIKRLSLASG-QGLVEF 568
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLL 1002
K E ++ L H +++K GCC ++ EK L+ EY+P SL +L P I L L
Sbjct 569 KNEAMLIAKLQHTNLVKLLGCCVEKDEK--MLIYEYMPNKSLDYFLFDPLRKIVLDWKLR 626
Query 1003 F--AQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
F + I +G+ YLH IHRD+ A N+LLD D KI DFG+A+ G + +
Sbjct 627 FRIMEGIIQGLLYLHKYSRLKVIHRDIKAGNILLDEDMNPKISDFGMARIF--GAQESKA 684
Query 1058 REDGDSPVFWY-APECLKEYKFYYASDVWSFGVTLYELL 1095
+ F Y +PE +E F SDV+SFGV + E++
Sbjct 685 NTKRVAGTFGYMSPEYFREGLFSAKSDVFSFGVLMLEII 723
Score = 54.7 bits (130), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 66/271 (24%), Positives = 110/271 (41%), Gaps = 46/271 (17%)
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
P+ GR E V +K L + + F A L++++ HT+L + G CV E ++
Sbjct 540 PVYKGRLIDGE-EVAIKRLSLASGQGLVEFKNEAMLIAKLQHTNLVKLLGCCVEKDEKML 598
Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKM--VVAQQLASALSYLENKN---LVHGNVCGRNI 740
+ EY+ + LD +L + + WK+ + + + L YL + ++H ++ NI
Sbjct 599 IYEYMPNKSLDYFLFDPLRKIVLDWKLRFRIMEGIIQGLLYLHKYSRLKVIHRDIKAGNI 658
Query 741 LLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIP----WLAPECLPGGANSLSTA 794
L L E +P K+SD G+ GA + +R+ +++PE G S
Sbjct 659 L-----LDEDMNP--KISDFGMARIFGAQESKANTKRVAGTFGYMSPEYFREGL--FSAK 709
Query 795 MDKWGFGATLLEIC---------FDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------- 837
D + FG +LEI D E PL R + +PS
Sbjct 710 SDVFSFGVLMLEIICGRKNNSFHHDSEGPLNLIVHVWNLFKENRVREVIDPSLGDSAVEN 769
Query 838 -----CPQLATLTSQCLTYEPTQRPSFRTIL 863
C Q+A L C+ RPS ++
Sbjct 770 PQVLRCVQVALL---CVQQNADDRPSMLDVV 797
>sp|Q852Q2|OSK1_ORYSJ Serine/threonine protein kinase OSK1 OS=Oryza
sativa subsp. japonica OX=39947 GN=OSK1 PE=1 SV=1
Length=505
Score = 92.8 bits (229), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 73/200 (37%), Positives = 100/200 (50%), Gaps = 16/200 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEH 958
+ LG G FGKV + + TG VA+K L + + K+EI ILR H H
Sbjct 18 KTLGIGSFGKVKI----AEHILTGHKVAIKILNRRKIKSMEMEEKVKREIKILRLFMHPH 73
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
II+ + + + +VMEYV G L DY+ + + + F QQI G+ Y H
Sbjct 74 IIRLYEVIDTPAD--IYVVMEYVKSGELFDYIVEKGRLQEEEARRFFQQIISGVEYCHRN 131
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL N+LLD+ VKI DFGL+ + +GH ++ SP + APE + K
Sbjct 132 MVVHRDLKPENLLLDSKCNVKIADFGLSNVMRDGH---FLKTSCGSPNY-AAPEVISG-K 186
Query 1078 FYYA--SDVWSFGVTLYELL 1095
Y DVWS GV LY LL
Sbjct 187 LYAGPEVDVWSCGVILYALL 206
Score = 34.7 bits (78), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 45/202 (22%), Positives = 81/202 (40%), Gaps = 18/202 (9%)
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726
H H+ ++ V + +V EYV+ G L ++ E+G + QQ+ S + Y
Sbjct 71 HPHIIRLYEVIDTPADIYVVMEYVKSGELFDYIV-EKGRLQEEEARRFFQQIISGVEYCH 129
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-----WLAP 781
+VH ++ N+LL + +K++D GL + R+ + + AP
Sbjct 130 RNMVVHRDLKPENLLL-------DSKCNVKIAD--FGLSNVMRDGHFLKTSCGSPNYAAP 180
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQ 840
E + G + +D W G L + G P + P+ + + LP P
Sbjct 181 EVISGKLYA-GPEVDVWSCGVILYALLC-GTLPFDDENIPNLFKKIKGGIYTLPSHLSPL 238
Query 841 LATLTSQCLTYEPTQRPSFRTI 862
L + L +P +R + R I
Sbjct 239 ARDLIPRMLVVDPMKRITIREI 260
>sp|Q94C95|ATG1A_ARATH Serine/threonine-protein kinase ATG1a OS=Arabidopsis
thaliana OX=3702 GN=ATG1A PE=1 SV=1
Length=626
Score = 93.2 bits (230), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 68/200 (34%), Positives = 106/200 (53%), Gaps = 17/200 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G F V L + +G VAVK + K P+ R +EI IL T+ H +II+
Sbjct 16 IGSGSFAVVWL----AKHRSSGLEVAVKEIDKKLLSPKVRDNLLKEISILSTIDHPNIIR 71
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ E G++ + LV+EY G L Y+ RH + A F +Q+ G+ L +H+I
Sbjct 72 FYEAIE-TGDR-IFLVLEYCSGGDLAGYINRHGKVPEAVAKHFMRQLALGLQVLQEKHFI 129
Query 1021 HRDLAARNVLLDNDR---LVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLKEY 1076
HRDL +N+LL + L+KIGDFG A+++ PE + E + APE ++
Sbjct 130 HRDLKPQNLLLSSKEVTPLLKIGDFGFARSLTPES-----MAETFCGSPLYMAPEIIRNQ 184
Query 1077 KFYYASDVWSFGVTLYELLT 1096
K+ +D+WS G L++L+T
Sbjct 185 KYDAKADLWSAGAILFQLVT 204
Score = 57.4 bits (137), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 60/246 (24%), Positives = 100/246 (41%), Gaps = 22/246 (9%)
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
K+L P D L + S++S + H ++ + G +V EY G L ++ R
Sbjct 44 KLLSPKVRDNLL---KEISILSTIDHPNIIRFYEAIETGDRIFLVLEYCSGGDLAGYINR 100
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
G VP A +QLA L L+ K+ +H ++ +N+LL+ ++ +P +K+ D G
Sbjct 101 -HGKVPEAVAKHFMRQLALGLQVLQEKHFIHRDLKPQNLLLS----SKEVTPLLKIGDFG 155
Query 762 VGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+L+ E E ++APE + D W GA L ++ G+ P
Sbjct 156 FA-RSLTPESMAETFCGSPLYMAPEIIRN--QKYDAKADLWSAGAILFQLV-TGKPPFDG 211
Query 818 RSPSEKEHFYQRQHRLPEPSC------PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
+ + H R L P P L L P +R +FR + +P
Sbjct 212 NNHIQLFHNIVRDTELKFPEDTRNEIHPDCVDLCRSLLRRNPIERLTFREFFNHMFLREP 271
Query 872 HNLADV 877
+ DV
Sbjct 272 RQIPDV 277
>sp|Q53UA7|TAOK3_RAT Serine/threonine-protein kinase TAO3 OS=Rattus
norvegicus OX=10116 GN=Taok3 PE=1 SV=1
Length=898
Score = 94.0 bits (232), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 71/203 (35%), Positives = 102/203 (50%), Gaps = 23/203 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956
+ ++G G FG V Y TN T E+VA+K + + G Q W+ +E+ L+ L H
Sbjct 27 LHEIGHGSFGAV----YFATNAHTNEVVAIKKM-SYSGKQTHEKWQDILKEVRFLQQLKH 81
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014
+ I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL
Sbjct 82 PNTIEYKGCY--LKEHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQGLAYL 138
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071
H IHRD+ A N+LL VK+ DFG A + + +P +W APE
Sbjct 139 HFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFV------GTP-YWMAPEVIL 191
Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094
+ E ++ D+WS G+T EL
Sbjct 192 AMDEGQYDGKVDIWSLGITCIEL 214
Score = 34.7 bits (78), Expect = 7.8, Method: Compositional matrix adjust.
Identities = 49/214 (23%), Positives = 75/214 (35%), Gaps = 42/214 (20%)
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781
L+YL +L+H ++ NILL G +KL+D G A V W+AP
Sbjct 135 LAYLHFHSLIHRDIKAGNILLTEPGQ-------VKLADFGSASMASPANSFVGTPYWMAP 187
Query 782 EC-LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840
E L +D W G T +E+ + S H Q P
Sbjct 188 EVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQN-------DSPT 240
Query 841 LAT---------LTSQCLTYEPTQRPSFRTILR-DLTRLQ--PHNLADVLTVNPDSPASD 888
L + CL P +RP+ +LR D R + P L D++ D+
Sbjct 241 LQSREWTDSFRRFVDYCLHKIPQERPAAAELLRHDFIRRERPPRVLIDLIQRTKDA---- 296
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922
+R+L + K+ + T +G
Sbjct 297 -----------VRELDNLQYRKMKKILFQETRNG 319
>sp|O42565|LIMK1_XENLA LIM domain kinase 1 OS=Xenopus laevis OX=8355
GN=limk1 PE=2 SV=1
Length=615
Score = 93.2 bits (230), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 62/199 (31%), Positives = 100/199 (50%), Gaps = 13/199 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG+ T+ TGE++ +K L R+ K E+ ++R L H H++K+
Sbjct 320 LGRGCFGQA----IKVTHRVTGEVMVMKELIRFDEETQRTFLK-EVKVMRCLEHPHVLKF 374
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYI 1020
G +K L + EY+P G+LR + Q + FA+ I GM YLH+ + I
Sbjct 375 IGVL--YKDKRLNFITEYIPGGTLRRVIKSMDTHCPWNQRVSFARDIAAGMTYLHSMNII 432
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV----FWYAPECLKEY 1076
HRDL + N L+ D + + +FGL++ +PE R V +W APE +
Sbjct 433 HRDLNSHNCLVREDGGLVVANFGLSRLIPEETRDLRKDRRKRYTVVGNPYWMAPEMINGR 492
Query 1077 KFYYASDVWSFGVTLYELL 1095
+ + DV+SFG+ + E++
Sbjct 493 SYDESVDVFSFGIVICEII 511
Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/228 (22%), Positives = 90/228 (39%), Gaps = 9/228 (4%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+V+K L + F + +M + H H+ GV + +TEY+ G L
Sbjct 340 MVMKELIRFDEETQRTFLKEVKVMRCLEHPHVLKFIGVLYKDKRLNFITEYIPGGTLRRV 399
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG----LAEGTSPF 754
++ H P ++ A+ +A+ ++YL + N++H ++ N L+ G G S
Sbjct 400 IKSMDTHCPWNQRVSFARDIAAGMTYLHSMNIIHRDLNSHNCLVREDGGLVVANFGLSRL 459
Query 755 IKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--FDGE 812
I + R V W+APE + G S ++D + FG + EI + +
Sbjct 460 IPEETRDLRKDRRKRYTVVGNPYWMAPEMING--RSYDESVDVFSFGIVICEIIGLVNAD 517
Query 813 APLQSRSPSEKEHFYQRQHRLPEPSC-PQLATLTSQCLTYEPTQRPSF 859
R+ + R P+C P C +P +RP F
Sbjct 518 PDYLPRTMDFGLNVRAFLDRFCPPNCPPGFFPSAVLCCDLDPEKRPRF 565
>sp|Q9NGW9|MKCB_DICDI Probable serine/threonine-protein kinase
mkcB OS=Dictyostelium discoideum OX=44689 GN=mkcB PE=2 SV=1
Length=714
Score = 93.6 bits (231), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 63/218 (29%), Positives = 107/218 (49%), Gaps = 17/218 (8%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
+P + K Y K +G+G FG V Y + +VA+K + Q + ++ E
Sbjct 430 EPALLKKMY-KDSDQVGKGGFGTV----YFAKSTKEKRLVAIKKMPHVTKRQQQQNFR-E 483
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
IL H +I+K C D+ + +L +VME++ G+ + L A+++
Sbjct 484 AAILAKCDHPNIVKLHTCHIDK-DSNLWIVMEFMEGGTFEEAAKAWKFNENNLAYVAKEL 542
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+G+ YLH H +HRDL + N+++ + VK+ DFGL + V + V SP FW
Sbjct 543 LKGLQYLHENHMVHRDLKSANIMMSVEGKVKLIDFGLCEDVATSTPMHMV----GSP-FW 597
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
APE +++ D+WSF ++L E+ ++Q PP
Sbjct 598 MAPEMIQQKYHSTPVDIWSFAISLLEM-----ANQRPP 630
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 39/162 (24%), Positives = 74/162 (46%), Gaps = 26/162 (16%)
Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKM-- 712
+ A+++++ H ++ +H + N+ +V E++E G + + AWK
Sbjct 481 FREAAILAKCDHPNIVKLHTCHIDKDSNLWIVMEFMEGGTFEEAAK--------AWKFNE 532
Query 713 ----VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV--GLGA 766
VA++L L YL ++VH ++ NI+++ G +KL D G+ +
Sbjct 533 NNLAYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEGK-------VKLIDFGLCEDVAT 585
Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ V W+APE + + ST +D W F +LLE+
Sbjct 586 STPMHMVGSPFWMAPEMIQQKYH--STPVDIWSFAISLLEMA 625
>sp|Q04759|KPCT_HUMAN Protein kinase C theta type OS=Homo sapiens
OX=9606 GN=PRKCQ PE=1 SV=3
Length=706
Score = 93.6 bits (231), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 70/209 (33%), Positives = 103/209 (49%), Gaps = 23/209 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI-LRTLYHEHIIK 961
LG+G FGKV L + TN + A+KALK D ++ + +L EH
Sbjct 386 LGKGSFGKVFLAEFKKTN----QFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFL 441
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
C Q +++L VMEY+ G L ++ H L++ +A +I G+ +LH++ +
Sbjct 442 THMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIV 501
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WYAPECLKE 1075
+RDL N+LLD D +KI DFG+ K G D + F + APE L
Sbjct 502 YRDLKLDNILLDKDGHIKIADFGMCKENMLG--------DAKTNTFCGTPDYIAPEILLG 553
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
K+ ++ D WSFGV LYE+L QSP
Sbjct 554 QKYNHSVDWWSFGVLLYEMLI----GQSP 578
>sp|A8C984|MYLK3_DANRE Myosin light chain kinase 3 OS=Danio rerio
OX=7955 GN=mylk3 PE=2 SV=1
Length=715
Score = 93.6 bits (231), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 71/202 (35%), Positives = 105/202 (52%), Gaps = 23/202 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG+V C + + +G +A K +K G + R K EI ++ L H ++I+
Sbjct 410 LGGGRFGQVH-KCAELS---SGLTLAAKIIKVR-GMKERDEVKNEIGVMNQLNHVNLIQL 464
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020
E + +L L+MEYV G L + + S L +L ++F +QICEG+ YLH Q+ +
Sbjct 465 YDAFESRT--NLTLIMEYVEGGELFERIIDESYQLTELDAIVFTRQICEGVQYLHQQYIL 522
Query 1021 HRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVRE----DGDSPVFWYAPECLK 1074
H DL N+L N +KI DFGLA+ YR RE + +P F APE +
Sbjct 523 HLDLKPENILCVNSTGNQIKIIDFGLARK-------YRPREKLKVNFGTPEFL-APEVVN 574
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ +D+WS GV Y LL+
Sbjct 575 YDFVSFPTDMWSVGVITYMLLS 596
Score = 35.4 bits (80), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 37/165 (22%), Positives = 69/165 (42%), Gaps = 11/165 (7%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
+M+Q++H +L ++ ++ EYVE G L + E + +V +Q+
Sbjct 452 VMNQLNHVNLIQLYDAFESRTNLTLIMEYVEGGELFERIIDESYQLTELDAIVFTRQICE 511
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---P 777
+ YL + ++H ++ NIL T IK+ D G+ RE+
Sbjct 512 GVQYLHQQYILHLDLKPENILCVN-----STGNQIKIIDFGLARKYRPREKLKVNFGTPE 566
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+LAPE + + +S D W G + + G +P + +E
Sbjct 567 FLAPEVV--NYDFVSFPTDMWSVG-VITYMLLSGLSPFMGDNDAE 608
>sp|Q8VHF0|MARK3_RAT MAP/microtubule affinity-regulating kinase
3 OS=Rattus norvegicus OX=10116 GN=Mark3 PE=1 SV=1
Length=797
Score = 93.6 bits (231), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 72/211 (34%), Positives = 103/211 (49%), Gaps = 16/211 (8%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQE 947
P + + R LK I G+G+F KV L + T G VA+K + K P +E
Sbjct 51 PHIGNYRLLKTI---GKGNFAKVKLARHILT----GREVAIKIIDKTQLNPTSLQKLFRE 103
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQ 1006
+ I++ L H +I+K E EK+L L+MEY G + DYL H + + +Q
Sbjct 104 VRIMKILNHPNIVKLFEVIET--EKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 161
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I + Y H + +HRDL A N+LLD D +KI DFG + G + G P
Sbjct 162 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKITDFGFSNEFTVGSKLDTF--CGSPP-- 217
Query 1067 WYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096
+ APE + K+ DVWS GV LY L++
Sbjct 218 YAAPELFQGKKYDGPEVDVWSLGVILYTLVS 248
Score = 40.0 bits (92), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 49/236 (21%), Positives = 93/236 (39%), Gaps = 22/236 (9%)
Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K++D + + + +M ++H ++ + V ++ EY G +
Sbjct 82 VAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVF 141
Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+L H M K A+ Q+ SA+ Y K +VH ++ N+LL
Sbjct 142 DYLV---AHGRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLL-------DADMN 191
Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
IK++D G + +++ P+ APE G +D W G L +
Sbjct 192 IKITDFGFS-NEFTVGSKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLV-S 248
Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
G P ++ E +E + ++R+P L + L P +R + I++D
Sbjct 249 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMKD 304
>sp|Q9ZUE0|PEK12_ARATH Proline-rich receptor-like protein kinase
PERK12 OS=Arabidopsis thaliana OX=3702 GN=PERK12 PE=2 SV=2
Length=720
Score = 93.6 bits (231), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 74/204 (36%), Positives = 101/204 (50%), Gaps = 24/204 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG C G++VAVK LKA G R +K E++I+ ++H H++
Sbjct 377 LGEGGFG-----CVYKGTLQDGKVVAVKQLKAGSGQGDRE-FKAEVEIISRVHHRHLVSL 430
Query 963 KG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHA 1016
G C DQ L+ EYV +L +L H GL L + A +G+AYLH
Sbjct 431 VGYCISDQHR---LLIYEYVSNQTLEHHL--HGKGLPVLEWSKRVRIAIGSAKGLAYLHE 485
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072
IHRD+ + N+LLD++ ++ DFGLA+ + R G F Y APE
Sbjct 486 DCHPKIIHRDIKSANILLDDEYEAQVADFGLARLNDTTQTHVSTRVMG---TFGYLAPEY 542
Query 1073 LKEYKFYYASDVWSFGVTLYELLT 1096
K SDV+SFGV L EL+T
Sbjct 543 ASSGKLTDRSDVFSFGVVLLELVT 566
Score = 41.2 bits (95), Expect = 0.070, Method: Compositional matrix adjust.
Identities = 66/269 (25%), Positives = 106/269 (39%), Gaps = 50/269 (19%)
Query 574 LNLSQLSFHRVDQKEITQ----LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
L Q F + EITQ + LG+G VY+G L ++GK+
Sbjct 352 LGSGQTHFSYEELAEITQGFARKNILGEGGFGCVYKGTL--------QDGKV-------- 395
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
V +K L F ++S+V H HL + G C+ +++ EY
Sbjct 396 ---------VAVKQLKAGSGQGDREFKAEVEIISRVHHRHLVSLVGYCISDQHRLLIYEY 446
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASA--LSYLENK---NLVHGNVCGRNILLAR 744
V + L+ L +G + W V + SA L+YL ++H ++ NILL
Sbjct 447 VSNQTLEHHLHG-KGLPVLEWSKRVRIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDD 505
Query 745 LGLAEGTSPFIKLSDPGVG-LGALSREERVERI----PWLAPECLPGGANSLSTAMDKWG 799
A+ ++D G+ L ++ R+ +LAPE G L+ D +
Sbjct 506 EYEAQ-------VADFGLARLNDTTQTHVSTRVMGTFGYLAPEYASSG--KLTDRSDVFS 556
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
FG LLE+ G P+ P +E +
Sbjct 557 FGVVLLELV-TGRKPVDQTQPLGEESLVE 584
>sp|O81906|B120_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase B120 OS=Arabidopsis thaliana OX=3702 GN=B120
PE=2 SV=1
Length=849
Score = 93.6 bits (231), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 86/281 (31%), Positives = 129/281 (46%), Gaps = 18/281 (6%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
K +LG G FG V + G +AVK L G Q +K EI ++ L H +
Sbjct 531 KENELGRGGFGPVYKGVLED-----GREIAVKRLSGKSG-QGVDEFKNEIILIAKLQHRN 584
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYL 1014
+++ GCC + EK LV EY+P SL +L + I + I G+ YL
Sbjct 585 LVRLLGCCFEGEEK--MLVYEYMPNKSLDFFLFDETKQALIDWKLRFSIIEGIARGLLYL 642
Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAP 1070
H IHRDL NVLLD + KI DFG+A+ +E VR G + +P
Sbjct 643 HRDSRLRIIHRDLKVSNVLLDAEMNPKISDFGMARIFGGNQNEANTVRVVGTYG--YMSP 700
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E E F SDV+SFGV L E+++ ++ ++ LIG A T R EL++
Sbjct 701 EYAMEGLFSVKSDVYSFGVLLLEIVSGKRNTSLRSSEHGSLIGYAWYLYTHGRSEELVDP 760
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
R+ + H+ C + A+ RP +++ +L++
Sbjct 761 KIRVTCSKREALRCIHVAMLCVQDSAAERPNMASVLLMLES 801
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 42/161 (26%), Positives = 74/161 (46%), Gaps = 14/161 (9%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM-- 712
F L++++ H +L + G C G E ++V EY+ + LD +L E + WK+
Sbjct 570 FKNEIILIAKLQHRNLVRLLGCCFEGEEKMLVYEYMPNKSLDFFLFDETKQALIDWKLRF 629
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSRE 770
+ + +A L YL + + + R++ ++ + L +P K+SD G+ G E
Sbjct 630 SIIEGIARGLLYLHRDSRLR--IIHRDLKVSNVLLDAEMNP--KISDFGMARIFGGNQNE 685
Query 771 ERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
R+ +++PE G S D + FG LLEI
Sbjct 686 ANTVRVVGTYGYMSPEYAMEGL--FSVKSDVYSFGVLLLEI 724
>sp|P92958|KIN11_ARATH SNF1-related protein kinase catalytic subunit
alpha KIN11 OS=Arabidopsis thaliana OX=3702 GN=KIN11
PE=1 SV=1
Length=512
Score = 92.4 bits (228), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 72/200 (36%), Positives = 100/200 (50%), Gaps = 16/200 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEH 958
+ LG G FGKV + + TG VA+K L + + ++EI ILR H H
Sbjct 24 KTLGIGSFGKVKI----AEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPH 79
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
II+ E + + +VMEYV G L DY+ + + + F QQI G+ Y H
Sbjct 80 IIRQYEVIETTSD--IYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRN 137
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL N+LLD+ +KI DFGL+ + +GH ++ SP + APE + K
Sbjct 138 MVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDGH---FLKTSCGSPNY-AAPEVISG-K 192
Query 1078 FYYA--SDVWSFGVTLYELL 1095
Y DVWS GV LY LL
Sbjct 193 LYAGPEVDVWSCGVILYALL 212
>sp|Q9FID9|Y5389_ARATH Probable receptor-like protein kinase At5g38990
OS=Arabidopsis thaliana OX=3702 GN=At5g38990 PE=2 SV=1
Length=880
Score = 93.6 bits (231), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 67/202 (33%), Positives = 97/202 (48%), Gaps = 16/202 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V Y DG +VAVK L+ Q + E+++L L H H++
Sbjct 531 IGVGGFGSV----YKGRIDGGATLVAVKRLEITSN-QGAKEFDTELEMLSKLRHVHLVSL 585
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ--QIC----EGMAYLHA 1016
G C+D E + LV EY+P G+L+D+L R L + + +IC G+ YLH
Sbjct 586 IGYCDDDNE--MVLVYEYMPHGTLKDHLFRRDKASDPPLSWKRRLEICIGAARGLQYLHT 643
Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRD+ N+LLD + + K+ DFGL++ P V + PE
Sbjct 644 GAKYTIIHRDIKTTNILLDENFVAKVSDFGLSRVGPTSASQTHVSTVVKGTFGYLDPEYY 703
Query 1074 KEYKFYYASDVWSFGVTLYELL 1095
+ SDV+SFGV L E+L
Sbjct 704 RRQILTEKSDVYSFGVVLLEVL 725
Score = 51.2 bits (121), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 57/209 (27%), Positives = 91/209 (44%), Gaps = 23/209 (11%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
GR G V +K L+ + + A F ++S++ H HL + G C E ++V EY
Sbjct 542 GRIDGGATLVAVKRLEITSNQGAKEFDTELEMLSKLRHVHLVSLIGYCDDDNEMVLVYEY 601
Query 690 VEHGPL-DVWLRRERGHV-PMAWK--MVVAQQLASALSYLENK---NLVHGNVCGRNILL 742
+ HG L D RR++ P++WK + + A L YL ++H ++ NILL
Sbjct 602 MPHGTLKDHLFRRDKASDPPLSWKRRLEICIGAARGLQYLHTGAKYTIIHRDIKTTNILL 661
Query 743 ARLGLAEGTSPFIKLSDPG---VGLGALSREERVERIP----WLAPECLPGGANSLSTAM 795
+A K+SD G VG + S+ + +L PE L+
Sbjct 662 DENFVA-------KVSDFGLSRVGPTSASQTHVSTVVKGTFGYLDPEYYR--RQILTEKS 712
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKE 824
D + FG LLE+ +QS P + +
Sbjct 713 DVYSFGVVLLEVLCCRPIRMQSVPPEQAD 741
>sp|Q05512|MARK2_MOUSE Serine/threonine-protein kinase MARK2 OS=Mus
musculus OX=10090 GN=Mark2 PE=1 SV=3
Length=776
Score = 93.6 bits (231), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 76/232 (33%), Positives = 114/232 (49%), Gaps = 18/232 (8%)
Query 870 QPHNLADVLTVNPDSPASD--PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+P + +++L + ++D P + + R LK I G+G+F KV L + TG+ V
Sbjct 27 KPSSKSNMLRGRNSATSADEQPHIGNYRLLKTI---GKGNFAKVKLARHI----LTGKEV 79
Query 928 AVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
AVK + K +E+ I++ L H +I+K E EK+L LVMEY G +
Sbjct 80 AVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIET--EKTLYLVMEYASGGEV 137
Query 987 RDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
DYL H + + +QI + Y H + +HRDL A N+LLD D +KI DFG +
Sbjct 138 FDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFS 197
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096
G++ G P + APE + K DVWS GV LY L++
Sbjct 198 NEFTFGNKLDTF--CGSPP--YAAPELFQGKKIDGPEVDVWSLGVILYTLVS 245
Score = 39.7 bits (91), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 22/236 (9%)
Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K++D + + + + +M ++H ++ + V +V EY G +
Sbjct 79 VAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVF 138
Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+L H M K A+ Q+ SA+ Y K +VH ++ N+LL
Sbjct 139 DYLV---AHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLL-------DADMN 188
Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
IK++D G + +++ P+ APE G +D W G L +
Sbjct 189 IKIADFGFS-NEFTFGNKLDTFCGSPPYAAPELFQGKKID-GPEVDVWSLGVILYTLV-S 245
Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
G P ++ E +E + ++R+P L + L P++R + I++D
Sbjct 246 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKD 301
>sp|B3MH43|PTK7_DROAN Tyrosine-protein kinase-like otk OS=Drosophila
ananassae OX=7217 GN=otk PE=3 SV=1
Length=1037
Score = 94.0 bits (232), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 64/257 (25%), Positives = 122/257 (47%), Gaps = 32/257 (12%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY G
Sbjct 784 QLVLVKALNKVKDEQACQEFRRQLDLLRGISHKGVVRLFGLCREKDPH--YMVLEYTDWG 841
Query 985 SLRDYLPRHS----------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARN 1028
L+ +L + + +Q+L A QI GM ++ + HRDLA RN
Sbjct 842 DLKQFLLATAGKVNTASAAATSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRN 901
Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
++ ++ +VK+ L K EY++ R + P+ W APEC++E ++ SD++++G
Sbjct 902 CVISSEFIVKVSYPALCKD-KYSREYHKHR-NTLLPIRWLAPECIQEDEYTTKSDIFAYG 959
Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148
V ++EL +++ P + I + Q L T + P + ++
Sbjct 960 VVVWELFNQ--ATKLPHEELTNEQVIQKSQAGTLEWT----------VAESTPDSLREIL 1007
Query 1149 KNCWETEASFRPTFENL 1165
+CW + RP+F L
Sbjct 1008 LSCWVSNPKERPSFSQL 1024
Score = 53.9 bits (128), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 60/256 (23%), Positives = 102/256 (40%), Gaps = 37/256 (14%)
Query 639 VVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V++K L+ + A F L+ +SH + + G+C + MV EY + G L
Sbjct 786 VLVKALNKVKDEQACQEFRRQLDLLRGISHKGVVRLFGLCREKDPHYMVLEYTDWGDLKQ 845
Query 698 WLRRERGHVPMAWK--------------MVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+L G V A + VA Q+A + + H ++ RN ++
Sbjct 846 FLLATAGKVNTASAAATSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRNCVI- 904
Query 744 RLGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDK 797
+S FI K+S P + SRE R I WLAPEC+ + +T D
Sbjct 905 -------SSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQ--EDEYTTKSDI 955
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH-----RLPEPSCPQLATLTSQCLTYE 852
+ +G + E+ F+ L + ++ + Q + E + L + C
Sbjct 956 FAYGVVVWEL-FNQATKLPHEELTNEQVIQKSQAGTLEWTVAESTPDSLREILLSCWVSN 1014
Query 853 PTQRPSFRTILRDLTR 868
P +RPSF + L++
Sbjct 1015 PKERPSFSQLGAALSK 1030
>sp|O49545|BAME1_ARATH Leucine-rich repeat receptor-like serine/threonine-protein
kinase BAM1 OS=Arabidopsis thaliana OX=3702
GN=BAM1 PE=1 SV=1
Length=1003
Score = 93.6 bits (231), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 84/271 (31%), Positives = 127/271 (47%), Gaps = 38/271 (14%)
Query 923 TGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
G++VAVK L A G H G+ EI L + H HI++ G C + E +L LV EY+
Sbjct 715 NGDLVAVKRLAAMSRGSSHDHGFNAEIQTLGRIRHRHIVRLLGFCSNH-ETNL-LVYEYM 772
Query 982 PLGSLRDYL-----------PRHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAAR 1027
P GSL + L R+ I L + +G+ YLH + +HRD+ +
Sbjct 773 PNGSLGEVLHGKKGGHLHWDTRYKIAL--------EAAKGLCYLHHDCSPLIVHRDVKSN 824
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
N+LLD++ + DFGLAK + + + S + APE K SDV+SF
Sbjct 825 NILLDSNFEAHVADFGLAKFLQDSGTSECMSAIAGS-YGYIAPEYAYTLKVDEKSDVYSF 883
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQ--GQMTVLRLTELLERGERLPRPDKCP---- 1141
GV L EL+T + P +F + + I Q +MT +L+ + PR P
Sbjct 884 GVVLLELVT----GRKPVGEFGDGVDIVQWVRKMTDSNKDSVLKVLD--PRLSSIPIHEV 937
Query 1142 CEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
V+++ C E +A RPT ++ IL +
Sbjct 938 THVFYVAMLCVEEQAVERPTMREVVQILTEI 968
Score = 43.1 bits (100), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 60/253 (24%), Positives = 105/253 (42%), Gaps = 45/253 (18%)
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGH 705
S HD F + ++ H H+ + G C N++V EY+ +G L +V ++ GH
Sbjct 731 SSHD--HGFNAEIQTLGRIRHRHIVRLLGFCSNHETNLLVYEYMPNGSLGEVLHGKKGGH 788
Query 706 VPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILL--------ARLGLAEGTSPF 754
+ + +A + A L YL + +VH +V NILL A GLA+ F
Sbjct 789 LHWDTRYKIALEAAKGLCYLHHDCSPLIVHRDVKSNNILLDSNFEAHVADFGLAK----F 844
Query 755 IKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLST--AMDKWGFGATLLEICF--- 809
++ S + A++ ++APE A +L D + FG LLE+
Sbjct 845 LQDSGTSECMSAIAGS-----YGYIAPEY----AYTLKVDEKSDVYSFGVVLLELVTGRK 895
Query 810 ------DGEAPLQ---SRSPSEKEHFYQ----RQHRLPEPSCPQLATLTSQCLTYEPTQR 856
DG +Q + S K+ + R +P + + C+ + +R
Sbjct 896 PVGEFGDGVDIVQWVRKMTDSNKDSVLKVLDPRLSSIPIHEVTHVFYVAMLCVEEQAVER 955
Query 857 PSFRTILRDLTRL 869
P+ R +++ LT +
Sbjct 956 PTMREVVQILTEI 968
>sp|Q6J9G0|STYK1_HUMAN Tyrosine-protein kinase STYK1 OS=Homo sapiens
OX=9606 GN=STYK1 PE=1 SV=4
Length=422
Score = 91.3 bits (225), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 76/273 (28%), Positives = 122/273 (45%), Gaps = 43/273 (16%)
Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKG 964
G + ++ DP+ + V +KALK G + I + L H+++++ +G
Sbjct 126 GPIFRANMNTGDPSKPKS---VILKALKEPAGLHEVQDFLGRIQFHQYLGKHKNLVQLEG 182
Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLF----------AQQICEGMA 1012
CC ++ L +V+E V G L +L R + LL+ +Q+ +
Sbjct 183 CCTEK--LPLYMVLEDVAQGDLLSFLWTCRRDVMTMDGLLYDLTEKQVYHIGKQVLLALE 240
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAP 1070
+L +H H D+AARN+L+ +D K+ GLA V Y R + P+ W AP
Sbjct 241 FLQEKHLFHGDVAARNILMQSDLTAKLCGLGLAYEV-----YTRGAISSTQTIPLKWLAP 295
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLTELL 1128
E L +DVWSFG+ LYE++T + PPT L E L
Sbjct 296 ERLLLRPASIRADVWSFGILLYEMVTLGAPPYPEVPPTSIL----------------EHL 339
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+R + + RP C +Y +MK+CW + RP+
Sbjct 340 QRRKIMKRPSSCTHTMYSIMKSCWRWREADRPS 372
Score = 56.2 bits (134), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 61/214 (29%), Positives = 90/214 (42%), Gaps = 29/214 (14%)
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV--------PMAWKMV--VAQ 716
H +L + G C MV E V G L +L R V + K V + +
Sbjct 174 HKNLVQLEGCCTEKLPLYMVLEDVAQGDLLSFLWTCRRDVMTMDGLLYDLTEKQVYHIGK 233
Query 717 QLASALSYLENKNLVHGNVCGRNILL-----ARL-GLAEGTSPFIKLSDPGVGLGALSRE 770
Q+ AL +L+ K+L HG+V RNIL+ A+L GL + + GA+S
Sbjct 234 QVLLALEFLQEKHLFHGDVAARNILMQSDLTAKLCGLGLAYEVYTR--------GAISST 285
Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
+ + + WLAPE L S+ D W FG L E+ G P P+ QR+
Sbjct 286 QTIP-LKWLAPERLLLRPASIRA--DVWSFGILLYEMVTLGAPPYPEVPPTSILEHLQRR 342
Query 831 HRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
+ P SC + ++ C + RPS R +
Sbjct 343 KIMKRPSSCTHTMYSIMKSCWRWREADRPSPREL 376
>sp|E9PT87|MYLK3_RAT Myosin light chain kinase 3 OS=Rattus norvegicus
OX=10116 GN=Mylk3 PE=1 SV=1
Length=786
Score = 93.2 bits (230), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 79/244 (32%), Positives = 113/244 (46%), Gaps = 38/244 (16%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRD--------------LGEGHFGKVSLYCYDPTN 920
A+ V D A+ P F R + I+D LG G FG+V + T
Sbjct 447 AEAAIVVLDDSAAPPAPFEHRVVS-IKDTLISTSYTVSQHEVLGGGRFGQV----HRCTE 501
Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
TG +A K +K + R K EI+I+ L H ++I+ E + S L+MEY
Sbjct 502 RSTGLALAAKIIKVK-NIKDREDVKNEINIMNQLSHVNLIQLYDAFESK--NSFTLIMEY 558
Query 981 VPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYIHRDLAARNVLL--DNDRL 1036
V G L D + L +L +LF +QICEG+ YLH + +H DL N+L
Sbjct 559 VDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQ 618
Query 1037 VKIGDFGLAKAVPEGHEYYRVRE----DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
+KI DFGLA+ Y+ RE + +P F APE + + +D+WS GV Y
Sbjct 619 IKIIDFGLAR-------RYKPREKLKVNFGTPEF-LAPEVVNYEFVSFPTDMWSVGVITY 670
Query 1093 ELLT 1096
LL+
Sbjct 671 MLLS 674
Score = 34.7 bits (78), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 38/170 (22%), Positives = 72/170 (42%), Gaps = 11/170 (6%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
++M+Q+SH +L ++ ++ EYV+ G L + E+ H+ ++ +Q+
Sbjct 529 NIMNQLSHVNLIQLYDAFESKNSFTLIMEYVDGGELFDRITDEKYHLTELDVVLFTRQIC 588
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776
+ YL ++H ++ NIL T IK+ D G+ RE+
Sbjct 589 EGVHYLHQHYILHLDLKPENIL-----CVSQTGHQIKIIDFGLARRYKPREKLKVNFGTP 643
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+LAPE + +S D W G + + G +P + +E +F
Sbjct 644 EFLAPEVV--NYEFVSFPTDMWSVG-VITYMLLSGLSPFLGETDAETMNF 690
>sp|Q93YN1|CRPK1_ARATH Cold-responsive protein kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=CRPK1 PE=1 SV=1
Length=390
Score = 90.9 bits (224), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 76/287 (26%), Positives = 127/287 (44%), Gaps = 39/287 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---EIDILRTLYHEHI 959
+GEG FG V C G++ A+K L A + R G K+ EI+++ + HE++
Sbjct 47 IGEGGFGSVYKGCLKD-----GKLAAIKVLSA----ESRQGVKEFLTEINVISEIQHENL 97
Query 960 IKYKGCC-------------EDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006
+K GCC E+ L Y G D+ R +I +
Sbjct 98 VKLYGCCVEGNHRILVYNFLENNSLDKTLLAGGYTRSGIQFDWSSRANICVG-------- 149
Query 1007 ICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+ +G+A+LH + H IHRD+ A N+LLD KI DFGLA+ +P + R G
Sbjct 150 VAKGLAFLHEEVRPHIIHRDIKASNILLDKYLSPKISDFGLARLMPPNMTHVSTRVAG-- 207
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVL 1122
+ + APE + +D++SFGV L E+++ + + PT++ L+ A
Sbjct 208 TIGYLAPEYAVRGQLTRKADIYSFGVLLMEIVSGRSNKNTRLPTEYQYLLERAWELYERN 267
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
L +L++ G + C + C + RP+ ++ +L
Sbjct 268 ELVDLVDSGLNGVFDAEEACRYLKIGLLCTQDSPKLRPSMSTVVRLL 314
Score = 60.8 bits (146), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 66/259 (25%), Positives = 108/259 (42%), Gaps = 43/259 (17%)
Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
+KVL F +++S++ H +L ++G CV G I+V ++E+ LD L
Sbjct 68 IKVLSAESRQGVKEFLTEINVISEIQHENLVKLYGCCVEGNHRILVYNFLENNSLDKTLL 127
Query 701 R---ERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752
R + W + + +A L++L + +++H ++ NILL + S
Sbjct 128 AGGYTRSGIQFDWSSRANICVGVAKGLAFLHEEVRPHIIHRDIKASNILLDKY-----LS 182
Query 753 PFIKLSDPGVGL----GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
P K+SD G+ RV I +LAPE G L+ D + FG L+EI
Sbjct 183 P--KISDFGLARLMPPNMTHVSTRVAGTIGYLAPEYAVRG--QLTRKADIYSFGVLLMEI 238
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL-------------------PEPSCPQLATLTSQC 848
G + +R P+E ++ +R L E +C L + C
Sbjct 239 -VSGRSNKNTRLPTEYQYLLERAWELYERNELVDLVDSGLNGVFDAEEACRYLK-IGLLC 296
Query 849 LTYEPTQRPSFRTILRDLT 867
P RPS T++R LT
Sbjct 297 TQDSPKLRPSMSTVVRLLT 315
>sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase
3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5
Length=753
Score = 93.2 bits (230), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 72/211 (34%), Positives = 103/211 (49%), Gaps = 16/211 (8%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQE 947
P + + R LK I G+G+F KV L + T G VA+K + K P +E
Sbjct 51 PHIGNYRLLKTI---GKGNFAKVKLARHILT----GREVAIKIIDKTQLNPTSLQKLFRE 103
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQ 1006
+ I++ L H +I+K E EK+L L+MEY G + DYL H + + +Q
Sbjct 104 VRIMKILNHPNIVKLFEVIET--EKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQ 161
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I + Y H + +HRDL A N+LLD D +KI DFG + G + G P
Sbjct 162 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTF--CGSPP-- 217
Query 1067 WYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096
+ APE + K+ DVWS GV LY L++
Sbjct 218 YAAPELFQGKKYDGPEVDVWSLGVILYTLVS 248
Score = 38.5 bits (88), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 48/236 (20%), Positives = 93/236 (39%), Gaps = 22/236 (9%)
Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K++D + + + +M ++H ++ + V ++ EY G +
Sbjct 82 VAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVF 141
Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+L H M K ++ Q+ SA+ Y K +VH ++ N+LL
Sbjct 142 DYLV---AHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLL-------DADMN 191
Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
IK++D G + +++ P+ APE G +D W G L +
Sbjct 192 IKIADFGFS-NEFTVGGKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLV-S 248
Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
G P ++ E +E + ++R+P L + L P +R + I++D
Sbjct 249 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKD 304
>sp|O14920|IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase
subunit beta OS=Homo sapiens OX=9606 GN=IKBKB PE=1 SV=1
Length=756
Score = 93.2 bits (230), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 68/207 (33%), Positives = 100/207 (48%), Gaps = 23/207 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + N TGE +A+K + + P++R W EI I+R L H +++
Sbjct 21 LGTGGFGNVIRW----HNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVVAA 76
Query 963 KGCCEDQGEKSLQ------LVMEYVPLGSLRDYLPR--HSIGLAQ--LLLFAQQICEGMA 1012
+ E G ++L L MEY G LR YL + + GL + +L I +
Sbjct 77 RDVPE--GMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALR 134
Query 1013 YLHAQHYIHRDLAARNVLLDN--DRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH IHRDL N++L RL+ KI D G AK + +G + + + A
Sbjct 135 YLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGS----LCTSFVGTLQYLA 190
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096
PE L++ K+ D WSFG +E +T
Sbjct 191 PELLEQQKYTVTVDYWSFGTLAFECIT 217
>sp|Q9FLZ3|KIN12_ARATH SNF1-related protein kinase catalytic subunit
alpha KIN12 OS=Arabidopsis thaliana OX=3702 GN=KIN12
PE=2 SV=1
Length=494
Score = 92.0 bits (227), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 71/200 (36%), Positives = 100/200 (50%), Gaps = 17/200 (9%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK----ADCGPQHRSGWKQEIDILRTLYH 956
+ LG G F KV L + TG VA+K L + G + + ++EI ILR L H
Sbjct 23 KTLGHGSFAKVKLALHV----ATGHKVAIKILNRSKIKNMGIEIKV--QREIKILRFLMH 76
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLH 1015
HII+ E + + +VMEYV G L DY+ + + + QQI G+ Y H
Sbjct 77 PHIIRQYEVIETPND--IYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCH 134
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRDL NVLLD+ +KI DFGL+ + +GH ++ SP + APE +
Sbjct 135 RNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGH---FLKTSCGSPNY-AAPEVISG 190
Query 1076 YKFYYASDVWSFGVTLYELL 1095
+ D+WS GV LY LL
Sbjct 191 KPYGPDVDIWSCGVILYALL 210
>sp|Q9LV48|PERK1_ARATH Proline-rich receptor-like protein kinase
PERK1 OS=Arabidopsis thaliana OX=3702 GN=PERK1 PE=1 SV=1
Length=652
Score = 92.8 bits (229), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 72/201 (36%), Positives = 103/201 (51%), Gaps = 18/201 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V +G+ VAVK LKA G R ++ E++I+ ++H H++
Sbjct 286 LGQGGFGYVHKGILP-----SGKEVAVKQLKAGSGQGERE-FQAEVEIISRVHHRHLVSL 339
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
G C G + L LV E+VP +L +L R ++ + L A +G++YLH
Sbjct 340 IGYCM-AGVQRL-LVYEFVPNNNLEFHLHGKGRPTMEWSTRLKIALGSAKGLSYLHEDCN 397
Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075
IHRD+ A N+L+D K+ DFGLAK + + + R G F Y APE
Sbjct 398 PKIIHRDIKASNILIDFKFEAKVADFGLAKIASDTNTHVSTRVMG---TFGYLAPEYAAS 454
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
K SDV+SFGV L EL+T
Sbjct 455 GKLTEKSDVFSFGVVLLELIT 475
Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 49/183 (27%), Positives = 79/183 (43%), Gaps = 27/183 (15%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F ++S+V H HL + G C+ G + ++V E+V + L+ L +G M W ++
Sbjct 321 FQAEVEIISRVHHRHLVSLIGYCMAGVQRLLVYEFVPNNNLEFHL-HGKGRPTMEWSTRL 379
Query 713 VVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+A A LSYL N ++H ++ NIL+ A K++D G+ A
Sbjct 380 KIALGSAKGLSYLHEDCNPKIIHRDIKASNILIDFKFEA-------KVADFGLAKIASDT 432
Query 770 EERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
V +LAPE G L+ D + FG LLE+ + R P +
Sbjct 433 NTHVSTRVMGTFGYLAPEYAASG--KLTEKSDVFSFGVVLLEL-------ITGRRPVDAN 483
Query 825 HFY 827
+ Y
Sbjct 484 NVY 486
>sp|O74456|PEF1_SCHPO Serine/threonine-protein kinase pef1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=pef1 PE=3 SV=2
Length=288
Score = 89.0 bits (219), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 60/205 (29%), Positives = 105/205 (51%), Gaps = 17/205 (8%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+++ LGEG + V Y N TGE+VA+K ++ D S +EI +++ L H
Sbjct 4 QRLEKLGEGTYAHV----YKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELRHP 59
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----SIGLAQLLLFAQQICEGMAY 1013
+I+ Q E L LV EY+ L+ Y+ + ++ +Q+ F QQ+ +G+++
Sbjct 60 NIMSLSDVL--QTENKLMLVFEYME-KDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISF 116
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072
H +HRDL +N+L+++ +K+ DFGLA+++ + + WY AP+
Sbjct 117 CHENRVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTF----SNEVVTLWYRAPDV 172
Query 1073 LKEYKFYYAS-DVWSFGVTLYELLT 1096
L + Y S D+WS G + E+ T
Sbjct 173 LLGSRVYSTSIDIWSVGCIMAEMAT 197
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/227 (24%), Positives = 97/227 (43%), Gaps = 44/227 (19%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV--LDPSH 648
+L LG+GT +VY+G+ RV G V LKV +D
Sbjct 5 RLEKLGEGTYAHVYKGQNRVTGE------------------------IVALKVIRIDADE 40
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP---LDVWLRRERGH 705
+ A E SLM ++ H ++ + V + ++V EY+E +D + +G
Sbjct 41 GTPSTAIREI-SLMKELRHPNIMSLSDVLQTENKLMLVFEYMEKDLKKYMDTY--GNQGA 97
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG---- 761
+P + QQL +S+ ++H ++ +N+L+ G +KL+D G
Sbjct 98 LPPSQVKNFTQQLLKGISFCHENRVLHRDLKPQNLLINSRGE-------LKLADFGLARS 150
Query 762 VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+G+ + V + + AP+ L G+ ST++D W G + E+
Sbjct 151 IGIPVNTFSNEVVTLWYRAPDVLL-GSRVYSTSIDIWSVGCIMAEMA 196
>sp|Q54XJ4|Y8901_DICDI Probable serine/threonine-protein kinase
DDB_G0278901 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0278901
PE=3 SV=1
Length=1495
Score = 93.6 bits (231), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 69/239 (29%), Positives = 114/239 (48%), Gaps = 22/239 (9%)
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL-LFAQ 1005
EI++L+ L H +I++Y +VME++ GSL + RH + L+ ++
Sbjct 72 EINLLKVLSHHNIVRYYEHIPSSSHS--YIVMEFIENGSLEKIIKRHGLLPESLVTVYIA 129
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
Q+ G+ YLH Q IHRD+ A N+L+ D +K+ DFG+A V + +P
Sbjct 130 QVLNGLEYLHRQGVIHRDIKAANLLISTDGSIKLADFGVATKVSDLSSDNPDDTFAGTP- 188
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+W APE ++ A DVWS G T+ ELLT +PP G+A +
Sbjct 189 YWMAPEVIQMQGISTACDVWSLGCTIIELLTG-----TPP-----YFGLAPAAALYKIVQ 238
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKY-QGQAP 1181
E + P P + + NC++ + + R + + L+ P +K+V + + QAP
Sbjct 239 E-----DHPPIPPGISAALKDFLLNCFKKDENIRSSAKQLLHHPWVKSVQIRNPETQAP 292
Score = 56.6 bits (135), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 45/161 (28%), Positives = 82/161 (51%), Gaps = 24/161 (15%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENI-------MVTEYVEHGPLDVWLRRERGHVPMAWKM 712
SLM++++ + H + VR E+I +V E++E+G L+ ++R G +P +
Sbjct 68 SLMAEINLLKVLSHHNI-VRYYEHIPSSSHSYIVMEFIENGSLEKIIKR-HGLLPESLVT 125
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-----LGAL 767
V Q+ + L YL + ++H ++ N+L++ G IKL+D GV L +
Sbjct 126 VYIAQVLNGLEYLHRQGVIHRDIKAANLLISTDG-------SIKLADFGVATKVSDLSSD 178
Query 768 SREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+ ++ P W+APE + +STA D W G T++E+
Sbjct 179 NPDDTFAGTPYWMAPEVI--QMQGISTACDVWSLGCTIIEL 217
>sp|O55076|CDK2_CRIGR Cyclin-dependent kinase 2 OS=Cricetulus
griseus OX=10029 GN=CDK2 PE=1 SV=1
Length=298
Score = 89.0 bits (219), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 65/205 (32%), Positives = 102/205 (50%), Gaps = 15/205 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955
+K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ L
Sbjct 4 FQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYV--PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013
H +I+K E L LV E++ L D I L + + Q+ +G+A+
Sbjct 60 HPNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASAVTGIPLPLIKSYLFQLLQGLAF 117
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072
H+ +HRDL +N+L++ + +K+ DFGLA+A Y + WY APE
Sbjct 118 CHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTY----THEVVTLWYRAPEI 173
Query 1073 LKEYKFY-YASDVWSFGVTLYELLT 1096
L K+Y A D+WS G E++T
Sbjct 174 LLGCKYYSTAVDIWSLGCIFAEMVT 198
Score = 37.0 bits (84), Expect = 0.91, Method: Compositional matrix adjust.
Identities = 49/194 (25%), Positives = 83/194 (43%), Gaps = 46/194 (24%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREER 772
QL L++ + ++H ++ +N+L+ AEG+ IKL+D G+ G+ +
Sbjct 110 QLLQGLAFCHSHRVLHRDLKPQNLLIN----AEGS---IKLADFGLARAFGVPVRTYTHE 162
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQS------RSPS 821
V + + APE L G STA+D W G E+ F G++ + +
Sbjct 163 VVTLWYRAPEIL-LGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGT 221
Query 822 EKEHFYQRQHRLPE--PSCPQLA----------------TLTSQCLTYEPTQRPSFRTIL 863
E + +P+ PS P+ A +L SQ L Y+P +R S + L
Sbjct 222 PDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAAL 281
Query 864 -----RDLTRLQPH 872
+D+T+ PH
Sbjct 282 AHPFFQDVTKPVPH 295
>sp|Q6P3Q4|STK4_XENTR Serine/threonine-protein kinase 4 OS=Xenopus
tropicalis OX=8364 GN=stk4 PE=2 SV=1
Length=485
Score = 91.7 bits (226), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 58/197 (29%), Positives = 98/197 (50%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V Y ++ T ++VA+K + + Q +EI I++ H+
Sbjct 33 LEKLGEGSYGSV----YKASHKETSQIVAIKQIPVESDLQE---IIKEIAIMQQCDSLHV 85
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VME+ GS+ D L + ++ + Q +G+ YLH
Sbjct 86 VKYYGSYFKNTD--LWIVMEFCGGGSISDIIRLRKQTLKEDETATILQSTLKGLEYLHFM 143
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+++ K+ DFG+A + + R FW APE ++E
Sbjct 144 RKIHRDIKAGNILLNSEGTAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVIQEIG 200
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 201 YNCVADIWSLGITAIEM 217
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 54/228 (24%), Positives = 87/228 (38%), Gaps = 21/228 (9%)
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
P D+ E A +M Q H+ +G + + +V E+ G + +R +
Sbjct 62 PVESDLQEIIKEIA-IMQQCDSLHVVKYYGSYFKNTDLWIVMEFCGGGSISDIIRLRKQT 120
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763
+ + Q L YL +H ++ NILL +EGT+ KL+D GV
Sbjct 121 LKEDETATILQSTLKGLEYLHFMRKIHRDIKAGNILLN----SEGTA---KLADFGVAGQ 173
Query 764 -LGALSREERVERIP-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+++ V P W+APE + G N ++ D W G T +E+ +G+ P P
Sbjct 174 LTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYAEIHP 229
Query 821 SEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R PE + CL P R S +L+
Sbjct 230 MRAIFMIPSNPPPTFRKPELWSKDFVDFINLCLVKNPELRSSATELLQ 277
>sp|Q8MVR1|GBPC_DICDI Cyclic GMP-binding protein C OS=Dictyostelium
discoideum OX=44689 GN=gbpC PE=1 SV=1
Length=2631
Score = 93.6 bits (231), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 76/242 (31%), Positives = 120/242 (50%), Gaps = 28/242 (12%)
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLL 1001
++ E+ + L H +++K G C + L + +EYV GSL L SI ++ L
Sbjct 944 FRHEVYYMSGLNHPNVMKISGFCI----QPLCMALEYVRYGSLYSLLSNSSIEISWGLRL 999
Query 1002 LFAQQICEGMAYLHAQH--YIHRDLAARNVLLD-----NDRLVKIGDFGLAKAVPEGHEY 1054
A +I +GM +LH+ + IHRDL + N+LL+ + + I DFG + A+ G
Sbjct 1000 QIASEIAKGMQHLHSHNPPVIHRDLKSPNILLNGITEGQNSVATIIDFGTSTALYGGAAL 1059
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
R D P+ W PE L + SDV+SFG+ L+EL T P +F
Sbjct 1060 IRCV---DQPL-WLGPEVLAGTAYSEPSDVYSFGIILWELYTRA----HPFDEF------ 1105
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
Q + +L + + RG R P CP E L+++CW E + RPTF +++ IL + +
Sbjct 1106 -QFGQWMSKLEDEIIRGLRPTIPPTCPPEYVELIQSCWTHEPNSRPTFTSIVEILGQIKK 1164
Query 1175 KY 1176
K+
Sbjct 1165 KF 1166
Score = 67.4 bits (163), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 75/271 (28%), Positives = 121/271 (45%), Gaps = 39/271 (14%)
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672
+G+ E DD D L+ R L+V H++ +Y MS ++H ++
Sbjct 919 NGNGEVMVYDDPDQLIEDR---------LRVFREFRHEV---YY-----MSGLNHPNVMK 961
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--L 730
+ G C++ M EYV +G L L + ++ +A ++A + +L + N +
Sbjct 962 ISGFCIQPL--CMALEYVRYGSLYSLLSNSSIEISWGLRLQIASEIAKGMQHLHSHNPPV 1019
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGV-----GLGALSREERVERIPWLAPECLP 785
+H ++ NILL G+ EG + + D G G AL R V++ WL PE L
Sbjct 1020 IHRDLKSPNILLN--GITEGQNSVATIIDFGTSTALYGGAALIR--CVDQPLWLGPEVLA 1075
Query 786 GGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP- 839
G A S D + FG L E+ FD Q S E E + +P P+CP
Sbjct 1076 GTA--YSEPSDVYSFGIILWELYTRAHPFDEFQFGQWMSKLEDEIIRGLRPTIP-PTCPP 1132
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ L C T+EP RP+F +I+ L +++
Sbjct 1133 EYVELIQSCWTHEPNSRPTFTSIVEILGQIK 1163
>sp|Q3UIZ8|MYLK3_MOUSE Myosin light chain kinase 3 OS=Mus musculus
OX=10090 GN=Mylk3 PE=1 SV=1
Length=795
Score = 92.8 bits (229), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 78/244 (32%), Positives = 113/244 (46%), Gaps = 38/244 (16%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRD--------------LGEGHFGKVSLYCYDPTN 920
A+ V D A+ P F R + I+D LG G FG+V + T
Sbjct 456 AEAAIVVLDDSAAPPAPFEHRVVS-IKDTLISAGYTVSQHEVLGGGRFGQV----HRCTE 510
Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
TG +A K +K + R K E++I+ L H ++I+ E + S L+MEY
Sbjct 511 RSTGLALAAKIIKVK-NVKDREDVKNEVNIMNQLSHVNLIQLYDAFESK--SSFTLIMEY 567
Query 981 VPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYIHRDLAARNVLL--DNDRL 1036
V G L D + L +L +LF +QICEG+ YLH + +H DL N+L
Sbjct 568 VDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQ 627
Query 1037 VKIGDFGLAKAVPEGHEYYRVRE----DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
+KI DFGLA+ Y+ RE + +P F APE + + +D+WS GV Y
Sbjct 628 IKIIDFGLAR-------RYKPREKLKVNFGTPEF-LAPEVVNYEFVSFPTDMWSVGVITY 679
Query 1093 ELLT 1096
LL+
Sbjct 680 MLLS 683
Score = 35.0 bits (79), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 38/170 (22%), Positives = 72/170 (42%), Gaps = 11/170 (6%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
++M+Q+SH +L ++ ++ EYV+ G L + E+ H+ ++ +Q+
Sbjct 538 NIMNQLSHVNLIQLYDAFESKSSFTLIMEYVDGGELFDRITDEKYHLTELDVVLFTRQIC 597
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776
+ YL ++H ++ NIL T IK+ D G+ RE+
Sbjct 598 EGVHYLHQHYILHLDLKPENIL-----CVSQTGHQIKIIDFGLARRYKPREKLKVNFGTP 652
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+LAPE + +S D W G + + G +P + +E +F
Sbjct 653 EFLAPEVV--NYEFVSFPTDMWSVG-VITYMLLSGLSPFLGETDAETMNF 699
>sp|A8XJW8|CST1_CAEBR Serine/threonine-protein kinase cst-1 OS=Caenorhabditis
briggsae OX=6238 GN=cst-1 PE=3 SV=2
Length=494
Score = 91.7 bits (226), Expect = 8e-18, Method: Compositional matrix adjust.
Identities = 57/194 (29%), Positives = 97/194 (50%), Gaps = 14/194 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG +G V + + +G ++A+K + D Q +EI I++ ++++KY
Sbjct 41 LGEGSYGSV----HKAIHKESGHVLAIKKVPVDTDLQE---IIKEISIMQQCKSKYVVKY 93
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G + L +VMEY GS+ D + R + ++ + +G+ YLH I
Sbjct 94 YGSYFKNSD--LWIVMEYCGAGSISDIMRARRKPLSEKEISAVLRDTLKGLQYLHDLKKI 151
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ A N+LL+ D + K+ DFG+A + + R FW APE ++E +
Sbjct 152 HRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIEEIGYDT 208
Query 1081 ASDVWSFGVTLYEL 1094
+D+WS G+T E+
Sbjct 209 KADIWSLGITAIEM 222
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 50/213 (23%), Positives = 81/213 (38%), Gaps = 21/213 (10%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q ++ +G + + +V EY G + +R R + V +
Sbjct 80 SIMQQCKSKYVVKYYGSYFKNSDLWIVMEYCGAGSISDIMRARRKPLSEKEISAVLRDTL 139
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL + +H ++ NILL G+A KL+D GV +++ V
Sbjct 140 KGLQYLHDLKKIHRDIKAGNILLNTDGIA-------KLADFGVAGQLTDTMAKRNTVIGT 192
Query 777 P-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ----H 831
P W+APE + T D W G T +E+ +G P P +
Sbjct 193 PFWMAPEVIE--EIGYDTKADIWSLGITAIEMA-EGRPPYSDIHPMRAIFMIPTKPPPTF 249
Query 832 RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ PE + CL +P +R +T LR
Sbjct 250 KKPEEWSSEFNDFIRCCLIKKPEER---KTALR 279
>sp|P50527|STE20_SCHPO Serine/threonine-protein kinase shk1/pak1
OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812
GN=shk1 PE=1 SV=2
Length=658
Score = 92.4 bits (228), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 67/280 (24%), Positives = 133/280 (48%), Gaps = 15/280 (5%)
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
Q+ S SE +H + + P + +T T + + PS + + R Q ++ A
Sbjct 310 QTLSTSETKHI-RPNNSTPYQRRAETSTKPKAVATPQKVEAPSAPRLQKRAPRQQSNDSA 368
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935
+ + +PT+ ++ ++K +G+G G V Y GT VA+K + +
Sbjct 369 VLAKLQSICNPKNPTLLYRNFVK----IGQGASGDV----YSARQVGTNLSVAIKKMNIN 420
Query 936 CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI 995
P+ + EI ++++ +H++I+ + + E L +VMEY+ GSL + + +++
Sbjct 421 QQPK-KEFIVNEILVMKSHHHKNIVNFIDTFFYKSE--LWMVMEYMRGGSLTEVVTNNTL 477
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
Q+ ++ EG+ +LH +HRD+ + N+LL +K+ DFG + + +
Sbjct 478 SEGQIAAICKETLEGLQHLHENGIVHRDIKSDNILLSLQGDIKLTDFGFCAQI-DSNMTK 536
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
R G +W APE + ++ + DVWS G+ E++
Sbjct 537 RTTMVGTP--YWMAPEVVTRKEYGFKVDVWSLGIMAIEMV 574
Score = 42.0 bits (97), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 58/245 (24%), Positives = 92/245 (38%), Gaps = 24/245 (10%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
R G L V +K ++ + +M H ++ E MV EY
Sbjct 403 ARQVGTNLSVAIKKMNINQQPKKEFIVNEILVMKSHHHKNIVNFIDTFFYKSELWMVMEY 462
Query 690 VEHGPL-DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ G L +V +A + ++ L +L +VH ++ NILL+ G
Sbjct 463 MRGGSLTEVVTNNTLSEGQIA---AICKETLEGLQHLHENGIVHRDIKSDNILLSLQG-- 517
Query 749 EGTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
IKL+D G + R V W+APE + +D W G
Sbjct 518 -----DIKLTDFGFCAQIDSNMTKRTTMVGTPYWMAPEVV--TRKEYGFKVDVWSLGIMA 570
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT-----LTSQCLTYEPTQRPSF 859
+E+ +GE P + +P + P+ S P+L + S+ LT P QRPS
Sbjct 571 IEMV-EGEPPYLNENPLRALYLIATIG-TPKISRPELLSSVFHDFLSKSLTVNPKQRPSS 628
Query 860 RTILR 864
+LR
Sbjct 629 GELLR 633
>sp|P14056|ARAF_RAT Serine/threonine-protein kinase A-Raf OS=Rattus
norvegicus OX=10116 GN=Araf PE=1 SV=1
Length=604
Score = 92.4 bits (228), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 70/257 (27%), Positives = 118/257 (46%), Gaps = 34/257 (13%)
Query 927 VAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
VAVK LK A + +K E+ +LR H +I+ + G G ++ ++ S
Sbjct 331 VAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG---FAIITQWCEGSS 387
Query 986 LRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
L +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L VKIGDFG
Sbjct 388 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFG 447
Query 1044 LAKAVPEGHEYYRVREDGDSP-------VFWYAPECLKEYK---FYYASDVWSFGVTLYE 1093
LA + R G P V W A E ++ + + SDV+++GV LYE
Sbjct 448 LATV--------KTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYE 499
Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
L+T ++ + + +G ++ L+++ CP + L+ +C +
Sbjct 500 LMTGSLPYSHIGSRDQIIFMVGRGYLSP-DLSKIFS---------NCPKAMRRLLTDCLK 549
Query 1154 TEASFRPTFENLIPILK 1170
+ RP F ++ ++
Sbjct 550 FQREERPLFPQILATIE 566
Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 67/255 (26%), Positives = 106/255 (42%), Gaps = 24/255 (9%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
GR G VLKV P+ A AF ++ + H ++ G R P ++T++
Sbjct 325 GRWHGDVAVKVLKVAQPTAEQ-AQAFKNEMQVLRKTRHVNILLFMGFMTR-PGFAIITQW 382
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
E L L M + VA+Q A + YL KN++H ++ NI L E
Sbjct 383 CEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIF-----LHE 437
Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802
G + +K+ D G+ GA E+ + W+A E + N S D + +G
Sbjct 438 GLT--VKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 495
Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855
L E+ G P ++ F R + P+ S CP+ + L + CL ++ +
Sbjct 496 VLYEL-MTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRRLLTDCLKFQREE 554
Query 856 RPSFRTILRDLTRLQ 870
RP F IL + LQ
Sbjct 555 RPLFPQILATIELLQ 569
>sp|O08678|MARK1_RAT Serine/threonine-protein kinase MARK1 OS=Rattus
norvegicus OX=10116 GN=Mark1 PE=1 SV=1
Length=793
Score = 92.8 bits (229), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 69/199 (35%), Positives = 99/199 (50%), Gaps = 13/199 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G+G+F KV L + T G VAVK + K P +E+ I++ L H +I
Sbjct 64 KTIGKGNFAKVKLARHVLT----GREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQH 1018
+K E EK+L LVMEY G + DYL H + + +QI + Y H +
Sbjct 120 VKLFEVIET--EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKC 177
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRDL A N+LLD D +KI DFG + G++ G P + APE + K+
Sbjct 178 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTF--CGSPP--YAAPELFQGKKY 233
Query 1079 YYAS-DVWSFGVTLYELLT 1096
DVWS GV LY L++
Sbjct 234 DGPEVDVWSLGVILYTLVS 252
>sp|O01700|DLK1_CAEEL Mitogen-activated protein kinase kinase
kinase dlk-1 OS=Caenorhabditis elegans OX=6239 GN=dlk-1 PE=1
SV=4
Length=928
Score = 93.2 bits (230), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 71/223 (32%), Positives = 107/223 (48%), Gaps = 26/223 (12%)
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQ 1005
EI LR L H++II++ G C +VMEY G L L R++I + +
Sbjct 171 EIKHLRHLRHQNIIEFLGVCSKS--PCYCIVMEYCSKGQLCTVLKSRNTITRELFAQWVK 228
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS-- 1063
+I +GM YLH IHRDL + N+L+ + +KI DFG + H ++ S
Sbjct 229 EIADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTS------HMQKKMDSTMMSFC 282
Query 1064 -PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
V W APE +K+ DV+SFGV L+E+LT ++P IAQ +
Sbjct 283 GTVSWMAPEMIKKQPCNEKVDVYSFGVVLWEMLTR----ETP------YANIAQMAIIFG 332
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
T +L LP P++ P + L+K C + RP+F ++
Sbjct 333 VGTNILS----LPMPEEAPKGLVLLIKQCLSQKGRNRPSFSHI 371
Score = 40.8 bits (94), Expect = 0.083, Method: Compositional matrix adjust.
Identities = 49/215 (23%), Positives = 86/215 (40%), Gaps = 22/215 (10%)
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726
H ++ GVC + P +V EY G L L + R + +++A + YL
Sbjct 180 HQNIIEFLGVCSKSPCYCIVMEYCSKGQLCTVL-KSRNTITRELFAQWVKEIADGMHYLH 238
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER----IPWLAPE 782
++H ++ NIL++ AE + IK+ D G + + + W+APE
Sbjct 239 QNKVIHRDLKSPNILIS----AEDS---IKICDFGTSHMQKKMDSTMMSFCGTVSWMAPE 291
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-----LPEPS 837
+ + +D + FG L E+ E P + ++ + +PE +
Sbjct 292 MIK--KQPCNEKVDVYSFGVVLWEM-LTRETPYA--NIAQMAIIFGVGTNILSLPMPEEA 346
Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
L L QCL+ + RPSF I + +P
Sbjct 347 PKGLVLLIKQCLSQKGRNRPSFSHIRQHWEIFKPE 381
>sp|Q54JQ1|MKCC_DICDI Probable serine/threonine-protein kinase
mkcC OS=Dictyostelium discoideum OX=44689 GN=mkcC PE=3 SV=1
Length=891
Score = 93.2 bits (230), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 74/275 (27%), Positives = 126/275 (46%), Gaps = 30/275 (11%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
K+ K ++ +G G FG S++ T D +A+K + R+ EI L
Sbjct 613 KKLYKNLKQIGSGGFG--SVFLAKSTVDKCE--IAIKKIAHVSAKAQRTNL-NEIGFLNF 667
Query 954 LYHEHIIKY--KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011
H +I+ Y +D ++ + MEY+ G+L + H+ + + A+ + EG+
Sbjct 668 CKHPNIVSYLRSHLVDD----TIWIAMEYMQGGTLTEASQGHTFNESCIAYVAKGMLEGL 723
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
YLHA + +HRD+ + N+++ D +KI DFGL + +E V G SP FW +PE
Sbjct 724 MYLHAHNIVHRDIKSGNIMMTIDGKIKIVDFGLC---VDANERKLVHMAG-SP-FWMSPE 778
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
++ + +D+WSF + L EL ++ PP + L + T E
Sbjct 779 MIRGESYGCPTDIWSFAICLLEL-----ANGEPPHRKSSLTAM---------FTTATEGC 824
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L +P++ H + C E + S R T E L+
Sbjct 825 AGLDKPERWTEHFTHFLNLCLEMDPSKRSTAEQLL 859
Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 48/188 (26%), Positives = 77/188 (41%), Gaps = 23/188 (12%)
Query 685 MVTEYVEHGPLDVWLRRERGHV-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+ EY++ G L +GH + VA+ + L YL N+VH ++ NI++
Sbjct 688 IAMEYMQGGTL---TEASQGHTFNESCIAYVAKGMLEGLMYLHAHNIVHRDIKSGNIMMT 744
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSRE-ERVERIP-WLAPECLPGGANSLSTAMDKWGFG 801
G IK+ D G+ + A R+ + P W++PE + G S D W F
Sbjct 745 IDGK-------IKIVDFGLCVDANERKLVHMAGSPFWMSPEMIRG--ESYGCPTDIWSFA 795
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQH-----RLPEPSCPQLATLTSQCLTYEPTQR 856
LLE+ +GE P R S F PE + CL +P++R
Sbjct 796 ICLLELA-NGEPP--HRKSSLTAMFTTATEGCAGLDKPERWTEHFTHFLNLCLEMDPSKR 852
Query 857 PSFRTILR 864
+ +L+
Sbjct 853 STAEQLLK 860
>sp|Q8VHJ5|MARK1_MOUSE Serine/threonine-protein kinase MARK1 OS=Mus
musculus OX=10090 GN=Mark1 PE=1 SV=2
Length=795
Score = 92.8 bits (229), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 69/199 (35%), Positives = 99/199 (50%), Gaps = 13/199 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G+G+F KV L + T G VAVK + K P +E+ I++ L H +I
Sbjct 64 KTIGKGNFAKVKLARHVLT----GREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQH 1018
+K E EK+L LVMEY G + DYL H + + +QI + Y H +
Sbjct 120 VKLFEVIET--EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKC 177
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRDL A N+LLD D +KI DFG + G++ G P + APE + K+
Sbjct 178 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTF--CGSPP--YAAPELFQGKKY 233
Query 1079 YYAS-DVWSFGVTLYELLT 1096
DVWS GV LY L++
Sbjct 234 DGPEVDVWSLGVILYTLVS 252
Score = 34.7 bits (78), Expect = 7.4, Method: Compositional matrix adjust.
Identities = 51/236 (22%), Positives = 93/236 (39%), Gaps = 22/236 (9%)
Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K++D + + + +M ++H ++ + V +V EY G +
Sbjct 86 VAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVF 145
Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+L H M K A+ Q+ SA+ Y K +VH ++ N+LL
Sbjct 146 DYLV---AHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLL-------DADMN 195
Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
IK++D G + +++ P+ APE G +D W G L +
Sbjct 196 IKIADFGFS-NEFTVGNKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLV-S 252
Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
G P ++ E +E + ++R+P L + L P +R S I++D
Sbjct 253 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKD 308
>sp|P04627|ARAF_MOUSE Serine/threonine-protein kinase A-Raf OS=Mus
musculus OX=10090 GN=Araf PE=1 SV=2
Length=604
Score = 92.4 bits (228), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 70/257 (27%), Positives = 118/257 (46%), Gaps = 34/257 (13%)
Query 927 VAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
VAVK LK A + +K E+ +LR H +I+ + G G ++ ++ S
Sbjct 331 VAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG---FAIITQWCEGSS 387
Query 986 LRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
L +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L VKIGDFG
Sbjct 388 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFG 447
Query 1044 LAKAVPEGHEYYRVREDGDSP-------VFWYAPECLKEYK---FYYASDVWSFGVTLYE 1093
LA + R G P V W A E ++ + + SDV+++GV LYE
Sbjct 448 LATV--------KTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYE 499
Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
L+T ++ + + +G ++ L+++ CP + L+ +C +
Sbjct 500 LMTGSLPYSHIGSRDQIIFMVGRGYLSP-DLSKIFS---------NCPKAMRRLLTDCLK 549
Query 1154 TEASFRPTFENLIPILK 1170
+ RP F ++ ++
Sbjct 550 FQREERPLFPQILATIE 566
Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 67/255 (26%), Positives = 106/255 (42%), Gaps = 24/255 (9%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
GR G VLKV P+ A AF ++ + H ++ G R P ++T++
Sbjct 325 GRWHGDVAVKVLKVAQPTAEQ-AQAFKNEMQVLRKTRHVNILLFMGFMTR-PGFAIITQW 382
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
E L L M + VA+Q A + YL KN++H ++ NI L E
Sbjct 383 CEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIF-----LHE 437
Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802
G + +K+ D G+ GA E+ + W+A E + N S D + +G
Sbjct 438 GLT--VKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 495
Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855
L E+ G P ++ F R + P+ S CP+ + L + CL ++ +
Sbjct 496 VLYEL-MTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRRLLTDCLKFQREE 554
Query 856 RPSFRTILRDLTRLQ 870
RP F IL + LQ
Sbjct 555 RPLFPQILATIELLQ 569
>sp|Q6PA14|STK4_XENLA Serine/threonine-protein kinase 4 OS=Xenopus
laevis OX=8355 GN=stk4 PE=2 SV=1
Length=485
Score = 91.7 bits (226), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V Y ++ T ++VA+K + + Q +EI I++ H+
Sbjct 33 LEKLGEGSYGSV----YKASHKETSQIVAIKQIPVESDLQE---IIKEISIMQQCDSPHV 85
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VME+ GS+ D L + ++ ++ Q +G+ YLH
Sbjct 86 VKYYGSYFKNTD--LWIVMEFCGGGSVSDIIRLRKQTLNEDEIATILQSTLKGLEYLHFM 143
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL + K+ DFG+A + + R FW APE ++E
Sbjct 144 RKIHRDIKAGNILLSCEGTAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVIQEIG 200
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 201 YNCVADIWSLGITAIEM 217
Score = 43.5 bits (101), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 51/214 (24%), Positives = 83/214 (39%), Gaps = 20/214 (9%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q H+ +G + + +V E+ G + +R + + + Q
Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEFCGGGSVSDIIRLRKQTLNEDEIATILQSTL 134
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL +H ++ NILL+ EGT+ KL+D GV +++ V
Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLS----CEGTA---KLADFGVAGQLTDTMAKRNTVIGT 187
Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830
P W+APE + G N ++ D W G T +E+ +G+ P P
Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYAEIHPMRAIFMIPSNPPPT 243
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R PE + CL P R S +L+
Sbjct 244 FRKPELWSKDFVDFINLCLVKNPELRSSATELLQ 277
>sp|Q9LT96|Y5977_ARATH Probable leucine-rich repeat receptor-like
protein kinase At5g49770 OS=Arabidopsis thaliana OX=3702
GN=At5g49770 PE=1 SV=1
Length=946
Score = 93.2 bits (230), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 82/262 (31%), Positives = 129/262 (49%), Gaps = 21/262 (8%)
Query 923 TGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
G+++A+K +A G Q +K EI++L ++H++++K G C DQ E+ LV EY+
Sbjct 655 NGQVIAIK--RAQQGSMQGAFEFKTEIELLSRVHHKNVVKLLGFCFDQKEQ--MLVYEYI 710
Query 982 PLGSLRDYLP-RHSIGL--AQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDR 1035
P GSLRD L ++ + L + L A +G+AYLH IHRD+ + N+LLD
Sbjct 711 PNGSLRDGLSGKNGVKLDWTRRLKIALGSGKGLAYLHELADPPIIHRDVKSNNILLDEHL 770
Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
K+ DFGL+K V + E V + + PE + SDV+ FGV + ELL
Sbjct 771 TAKVADFGLSKLVGD-PEKAHVTTQVKGTMGYLDPEYYMTNQLTEKSDVYGFGVVMLELL 829
Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLR----LTELLERGERLPRPDKCPCEVY-HLMKN 1150
T +SP + ++ + +M R L ELL+ + E Y +
Sbjct 830 T----GKSPIDRGSYVVKEVKKKMDKSRNLYDLQELLDTTIIQNSGNLKGFEKYVDVALQ 885
Query 1151 CWETEASFRPTFENLIPILKTV 1172
C E E RPT ++ L+++
Sbjct 886 CVEPEGVNRPTMSEVVQELESI 907
Score = 49.3 bits (116), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 59/244 (24%), Positives = 100/244 (41%), Gaps = 40/244 (16%)
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW- 710
A F L+S+V H ++ + G C E ++V EY+ +G L L + G V + W
Sbjct 672 AFEFKTEIELLSRVHHKNVVKLLGFCFDQKEQMLVYEYIPNGSLRDGLSGKNG-VKLDWT 730
Query 711 -KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--L 764
++ +A L+YL + ++H +V NILL A K++D G+ +
Sbjct 731 RRLKIALGSGKGLAYLHELADPPIIHRDVKSNNILLDEHLTA-------KVADFGLSKLV 783
Query 765 GALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
G + ++ +L PE N L+ D +GFG +LE+ G++P+ S
Sbjct 784 GDPEKAHVTTQVKGTMGYLDPEYYM--TNQLTEKSDVYGFGVVMLEL-LTGKSPIDRGSY 840
Query 821 SEKE---------HFYQRQHRLPEPSCPQLATLTS---------QCLTYEPTQRPSFRTI 862
KE + Y Q L L QC+ E RP+ +
Sbjct 841 VVKEVKKKMDKSRNLYDLQELLDTTIIQNSGNLKGFEKYVDVALQCVEPEGVNRPTMSEV 900
Query 863 LRDL 866
+++L
Sbjct 901 VQEL 904
>sp|Q9ASQ6|Y1972_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g29720 OS=Arabidopsis thaliana OX=3702
GN=RFK1 PE=2 SV=3
Length=1019
Score = 93.2 bits (230), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 85/280 (30%), Positives = 136/280 (49%), Gaps = 27/280 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG V +DGT ++AVK L + +R + EI ++ L H +++K
Sbjct 679 LGEGGFGSV---FKGELSDGT--IIAVKQLSSKSSQGNRE-FVNEIGMISGLNHPNLVKL 732
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA----YLH-- 1015
GCC ++ + L LV EY+ SL L ++S+ L Q+IC G+A +LH
Sbjct 733 YGCCVERDQ--LLLVYEYMENNSLALALFGQNSLKLDWAA--RQKICVGIARGLEFLHDG 788
Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
A +HRD+ NVLLD D KI DFGLA+ H + + G + + APE
Sbjct 789 SAMRMVHRDIKTTNVLLDTDLNAKISDFGLARLHEAEHTHISTKVAG--TIGYMAPEYAL 846
Query 1075 EYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ +DV+SFGV E+++ ++ Q + LI A +T+ + ++LE +R
Sbjct 847 WGQLTEKADVYSFGVVAMEIVSGKSNTKQQGNADSVSLINWA---LTLQQTGDILEIVDR 903
Query 1134 LPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170
+ + E ++K C + S RPT + +L+
Sbjct 904 MLEGEFNRSEAVRMIKVALVCTNSSPSLRPTMSEAVKMLE 943
Score = 38.5 bits (88), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 41/164 (25%), Positives = 72/164 (44%), Gaps = 22/164 (13%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMV 713
F ++S ++H +L ++G CV + ++V EY+E+ L + L + + A +
Sbjct 714 FVNEIGMISGLNHPNLVKLYGCCVERDQLLLVYEYMENNSLALALFGQNSLKLDWAARQK 773
Query 714 VAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ +A L +L + + +VH ++ N+LL T K+SD GL L
Sbjct 774 ICVGIARGLEFLHDGSAMRMVHRDIKTTNVLL-------DTDLNAKISD--FGLARLHEA 824
Query 771 ERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
E I ++APE G L+ D + FG +EI
Sbjct 825 EHTHISTKVAGTIGYMAPEYALWG--QLTEKADVYSFGVVAMEI 866
>sp|Q9LX66|HERK_ARATH Receptor-like protein kinase HERK 1 OS=Arabidopsis
thaliana OX=3702 GN=HERK1 PE=1 SV=1
Length=830
Score = 92.8 bits (229), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 75/230 (33%), Positives = 118/230 (51%), Gaps = 27/230 (12%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHE 957
R++G G FGKV NDGT VAVK P+ + G ++ EI++L H
Sbjct 489 RNIGVGGFGKV---YKGELNDGT--KVAVKR----GNPKSQQGLAEFRTEIEMLSQFRHR 539
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ-QICEGMA---- 1012
H++ G C++ E + L+ EY+ G+++ +L + GL L + +IC G A
Sbjct 540 HLVSLIGYCDENNE--MILIYEYMENGTVKSHL--YGSGLPSLTWKQRLEICIGAARGLH 595
Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH ++ IHRD+ + N+LLD + + K+ DFGL+K PE + + V +
Sbjct 596 YLHTGDSKPVIHRDVKSANILLDENFMAKVADFGLSKTGPELDQTH-VSTAVKGSFGYLD 654
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
PE + + SDV+SFGV L+E+L C PT E++ +A+ M
Sbjct 655 PEYFRRQQLTDKSDVYSFGVVLFEVL--CARPVIDPTLPREMVNLAEWAM 702
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 61/252 (24%), Positives = 99/252 (39%), Gaps = 28/252 (11%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K +P F ++SQ H HL + G C E I++ EY+E+G +
Sbjct 509 KVAVKRGNPKSQQGLAEFRTEIEMLSQFRHRHLVSLIGYCDENNEMILIYEYMENGTVKS 568
Query 698 WLRRERGHVPMAWK--MVVAQQLASALSYL---ENKNLVHGNVCGRNILLARLGLAEGTS 752
L G + WK + + A L YL ++K ++H +V NILL +A+
Sbjct 569 HLYGS-GLPSLTWKQRLEICIGAARGLHYLHTGDSKPVIHRDVKSANILLDENFMAKVAD 627
Query 753 PFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI---- 807
LS G L V+ +L PE L+ D + FG L E+
Sbjct 628 --FGLSKTGPELDQTHVSTAVKGSFGYLDPEYFR--RQQLTDKSDVYSFGVVLFEVLCAR 683
Query 808 -CFDGEAPLQSRSPSEKEHFYQRQHRLPE------------PSCPQLATLTSQCLTYEPT 854
D P + + +E +Q++ +L + S + A +CL
Sbjct 684 PVIDPTLPREMVNLAEWAMKWQKKGQLDQIIDQSLRGNIRPDSLRKFAETGEKCLADYGV 743
Query 855 QRPSFRTILRDL 866
RPS +L +L
Sbjct 744 DRPSMGDVLWNL 755
>sp|P43450|CDK2_CARAU Cyclin-dependent kinase 2 OS=Carassius auratus
OX=7957 GN=cdk2 PE=1 SV=1
Length=298
Score = 89.0 bits (219), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 65/205 (32%), Positives = 100/205 (49%), Gaps = 15/205 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955
+K+ +GEG +G V Y N TGE VA+K ++ D + S +EI +L+ L
Sbjct 4 FQKVEKIGEGTYGVV----YKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELN 59
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYV--PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013
H +I+K E L LV E++ L D I L + + Q+ +G+A+
Sbjct 60 HPNIVKLHDVI--HTENKLYLVFEFLHQDLKRFMDSSTVTGISLPLVKSYLFQLLQGLAF 117
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072
H+ +HRDL +N+L++ +K+ DFGLA+A Y + WY APE
Sbjct 118 CHSHRVLHRDLKPQNLLINAQGEIKLADFGLARAFGVPVRTY----THEVVTLWYRAPEI 173
Query 1073 LKEYKFY-YASDVWSFGVTLYELLT 1096
L K+Y A D+WS G E++T
Sbjct 174 LLGCKYYSTAVDIWSLGCIFAEMIT 198
Score = 34.7 bits (78), Expect = 5.3, Method: Compositional matrix adjust.
Identities = 68/328 (21%), Positives = 127/328 (39%), Gaps = 62/328 (19%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDP-EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
++ +G+GT VY+ + +V G ++ ++D E VP
Sbjct 6 KVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVP-------------------- 45
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
+ A E SL+ +++H ++ +H V + +V E++ + +
Sbjct 46 --STAIREI-SLLKELNHPNIVKLHDVIHTENKLYLVFEFLHQDLKRFMDSSTVTGISLP 102
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLG 765
QL L++ + ++H ++ +N+L+ A+G IKL+D G+ G+
Sbjct 103 LVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLIN----AQGE---IKLADFGLARAFGVP 155
Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQSRSP 820
+ V + + APE L G STA+D W G E+ F G+
Sbjct 156 VRTYTHEVVTLWYRAPEILLG-CKYYSTAVDIWSLGCIFAEMITRKALFPGD-------- 206
Query 821 SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR-DLTRLQP-------H 872
SE + ++ L P +TS P +PSF R DL+++ P
Sbjct 207 SEIDQLFRIFRTLGTPDESIWPGVTSM-----PDYKPSFPKWARQDLSKVVPPLDEDGRD 261
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKI 900
L +L +P+ S R+ + +
Sbjct 262 LLGQMLIYDPNKRISAKNALVHRFFRDV 289
>sp|P51954|NEK1_MOUSE Serine/threonine-protein kinase Nek1 OS=Mus
musculus OX=10090 GN=Nek1 PE=1 SV=2
Length=1203
Score = 93.2 bits (230), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 58/201 (29%), Positives = 102/201 (51%), Gaps = 11/201 (5%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+++ +GEG FGK L T DG ++ + + + R ++E+ +L + H +
Sbjct 6 RLQKIGEGSFGKAVLV--KSTEDGRHYVIKEINI-SRMSDKERQESRREVAVLANMKHPN 62
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLH 1015
I++YK E+ G SL +VM+Y G L + L Q+L + QIC + ++H
Sbjct 63 IVQYKESFEENG--SLYIVMDYCEGGDLFKRINAQKGALFQEDQILDWFVQICLALKHVH 120
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ +HRD+ ++N+ L D V++GDFG+A+ + E R ++ +PE +
Sbjct 121 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELART---CIGTPYYLSPEICEN 177
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
+ SD+W+ G LYEL T
Sbjct 178 KPYNNKSDIWALGCVLYELCT 198
>sp|B4HNW4|PTK7_DROSE Tyrosine-protein kinase-like otk OS=Drosophila
sechellia OX=7238 GN=otk PE=3 SV=1
Length=1029
Score = 92.8 bits (229), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 63/259 (24%), Positives = 123/259 (47%), Gaps = 31/259 (12%)
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
G ++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY
Sbjct 774 GLDQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPH--YMVLEYT 831
Query 982 PLGSLRDYLPRHS---------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
G L+ +L + + +Q+L A QI GM ++ + HRDLA
Sbjct 832 DWGDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLAT 891
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RN ++ ++ +VK+ L K EY++ R + P+ W APEC++E ++ SD+++
Sbjct 892 RNCVISSEFIVKVSYPALCKD-KYSREYHKHR-NTLLPIRWLAPECIQEDEYTTKSDIFA 949
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
+GV ++EL +++ P + + + Q L + + P +
Sbjct 950 YGVVVWELFNQ--ATKLPHEELTNEQVVQRSQAGSLEWS----------VAEATPDSLRE 997
Query 1147 LMKNCWETEASFRPTFENL 1165
++ +CW + RP+F L
Sbjct 998 ILLSCWVSNPKERPSFSQL 1016
Score = 55.5 bits (132), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 64/259 (25%), Positives = 103/259 (40%), Gaps = 44/259 (17%)
Query 639 VVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V++K L+ + A F L+ +SH + + G+C + MV EY + G L
Sbjct 779 VLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDWGDLKQ 838
Query 698 WLRRERGHVPMAWK-------------MVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+L G V A + VA Q+A + + H ++ RN ++
Sbjct 839 FLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRNCVI-- 896
Query 745 LGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKW 798
+S FI K+S P + SRE R I WLAPEC+ + +T D +
Sbjct 897 ------SSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQ--EDEYTTKSDIF 948
Query 799 GFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQH------RLPEPSCPQLATLTSQCL 849
+G + E+ F+ L P E+ E QR + E + L + C
Sbjct 949 AYGVVVWEL-FNQATKL----PHEELTNEQVVQRSQAGSLEWSVAEATPDSLREILLSCW 1003
Query 850 TYEPTQRPSFRTILRDLTR 868
P +RPSF + L++
Sbjct 1004 VSNPKERPSFSQLGAALSK 1022
>sp|O70146|TESK1_MOUSE Dual specificity testis-specific protein
kinase 1 OS=Mus musculus OX=10090 GN=Tesk1 PE=1 SV=3
Length=627
Score = 92.0 bits (227), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 63/199 (32%), Positives = 102/199 (51%), Gaps = 16/199 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G F +V Y + +G+++ +K K P +RS +E+ ++ L H +I+++
Sbjct 58 IGAGFFSEV----YKVRHRQSGQVMVLKMNKL---PSNRSNTLREVQLMNRLRHPNILRF 110
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G C QG+ L + EY+ G+L L + L A I +G+ YLHA+ H
Sbjct 111 MGVCVHQGQ--LHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIAQGLRYLHAKGVFH 168
Query 1022 RDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVFWYAPECLKEY 1076
RDL ++N L+ D +GDFGLA+ +P E R SP +W APE L+
Sbjct 169 RDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGTRKEPLAVVGSP-YWMAPEVLRGE 227
Query 1077 KFYYASDVWSFGVTLYELL 1095
+ +DV++FG+ L EL+
Sbjct 228 LYDEKADVFAFGIVLCELI 246
Score = 44.7 bits (104), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 63/264 (24%), Positives = 107/264 (41%), Gaps = 51/264 (19%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
R GQ + + + L PS+ L LM+++ H ++ GVCV + +TEY+
Sbjct 72 RQSGQVMVLKMNKL-PSNRSNTL---REVQLMNRLRHPNILRFMGVCVHQGQLHALTEYM 127
Query 691 EHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLAR---- 744
G L+ L P++W ++ +A +A L YL K + H ++ +N L+ R
Sbjct 128 NGGTLEQLLSSPE---PLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRREDRG 184
Query 745 -------LGLAEGTSPFIKLS--DPGVGLGALSREERVERIPWLAPECLPGGANSLSTAM 795
GLAE + + + +P +G+ W+APE L G
Sbjct 185 FTAVVGDFGLAEKIPVYREGTRKEPLAVVGSPY---------WMAPEVLRG--ELYDEKA 233
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---------HRLPEPSCP-QLATLT 845
D + FG L E L +R P++ ++ + + L CP L
Sbjct 234 DVFAFGIVLCE--------LIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLA 285
Query 846 SQCLTYEPTQRPSFRTILRDLTRL 869
C + EP+ R F I + L ++
Sbjct 286 IHCCSMEPSTRAPFTEITQHLEQI 309
>sp|Q9QY78|IKKB_RAT Inhibitor of nuclear factor kappa-B kinase
subunit beta OS=Rattus norvegicus OX=10116 GN=Ikbkb PE=1 SV=1
Length=757
Score = 92.4 bits (228), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 68/207 (33%), Positives = 100/207 (48%), Gaps = 23/207 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + N TGE +A+K + + P++R W EI I+R L H +++
Sbjct 21 LGTGGFGNVIRW----HNQVTGEQIAIKQCRQELSPKNRDRWCLEIQIMRRLNHPNVVAA 76
Query 963 KGCCEDQGEKSLQ------LVMEYVPLGSLRDYLPR--HSIGLAQ--LLLFAQQICEGMA 1012
+ E G ++L L MEY G LR YL + + GL + +L I +
Sbjct 77 RDVPE--GMQNLAPNDLPLLAMEYCQGGDLRRYLNQFENCCGLREGAILTLLSDIASALR 134
Query 1013 YLHAQHYIHRDLAARNVLLDN--DRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH IHRDL N++L RL+ KI D G AK + +G + + + A
Sbjct 135 YLHENRIIHRDLKPENIVLQQGEKRLIHKIIDLGYAKELDQGS----LCTSFVGTLQYLA 190
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096
PE L++ K+ D WSFG +E +T
Sbjct 191 PELLEQQKYTVTVDYWSFGTLAFECIT 217
>sp|Q60855|RIPK1_MOUSE Receptor-interacting serine/threonine-protein
kinase 1 OS=Mus musculus OX=10090 GN=Ripk1 PE=1 SV=1
Length=656
Score = 92.0 bits (227), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 79/275 (29%), Positives = 124/275 (45%), Gaps = 31/275 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
DL G FGKVSL CY ++ G ++ K ++ +E ++ L H ++K
Sbjct 22 DLDSGGFGKVSL-CYHRSH---GFVILKKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVVK 77
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G ++G SL VMEY+ G+L L + L+ + EGM YLH + I
Sbjct 78 LLGIIIEEGNYSL--VMEYMEKGNLMHVLKTQIDVPLSLKGRIIVEAIEGMCYLHDKGVI 135
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLA------KAVPEGHEYYR-----VREDGDSPVFWYA 1069
H+DL N+L+D D +KI D G+A K E + +++ +++ A
Sbjct 136 HKDLKPENILVDRDFHIKIADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMA 195
Query 1070 PECLKEY--KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
PE L + K SDV+SFG+ L+ + + ++ +I I G + E+
Sbjct 196 PEHLNDINAKPTEKSDVYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNRP--NVEEI 253
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
LE CP E+ LM+ CW+ RPTF
Sbjct 254 LEY---------CPREIISLMERCWQAIPEDRPTF 279
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 57/284 (20%), Positives = 117/284 (41%), Gaps = 40/284 (14%)
Query 639 VVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V+LK + P+ + E +M ++ H+ + + G+ + +V EY+E G L
Sbjct 42 VILKKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVVKLLGIIIEEGNYSLVMEYMEKGNL- 100
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+ + + + VP++ K + + + YL +K ++H ++ NIL+ R IK
Sbjct 101 MHVLKTQIDVPLSLKGRIIVEAIEGMCYLHDKGVIHKDLKPENILVDR-------DFHIK 153
Query 757 LSDPGVG------------------LGALSREERVERIPWLAPECLPGGANSLSTAMDKW 798
++D GV + + +++ + ++APE L + D +
Sbjct 154 IADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMAPEHLNDINAKPTEKSDVY 213
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-----CP-QLATLTSQCLTYE 852
FG L I F + P ++ +E+ + P CP ++ +L +C
Sbjct 214 SFGIVLWAI-FAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPREIISLMERCWQAI 272
Query 853 PTQRPSFRTILRD-----LTRLQPHNLADVLTVNPDSPASDPTV 891
P RP+F I + L+ + + DV ++ + P P +
Sbjct 273 PEDRPTFLGIEEEFRPFYLSHFEEYVEEDVASLKKEYPDQSPVL 316
>sp|Q9NB31|CST1_CAEEL Serine/threonine-protein kinase cst-1 OS=Caenorhabditis
elegans OX=6239 GN=cst-1 PE=1 SV=1
Length=497
Score = 91.3 bits (225), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 57/194 (29%), Positives = 97/194 (50%), Gaps = 14/194 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG +G V + + +G ++A+K + D Q +EI I++ ++++KY
Sbjct 41 LGEGSYGSV----HKAIHRESGHVLAIKKVPVDTDLQE---IIKEISIMQQCKSKYVVKY 93
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G + L +VMEY GS+ D + R + ++ + +G+ YLH I
Sbjct 94 YGSYFKHSD--LWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKI 151
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ A N+LL+ D + K+ DFG+A + + R FW APE ++E +
Sbjct 152 HRDIKAGNILLNTDGIAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIEEIGYDT 208
Query 1081 ASDVWSFGVTLYEL 1094
+D+WS G+T E+
Sbjct 209 KADIWSLGITAIEM 222
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 50/213 (23%), Positives = 81/213 (38%), Gaps = 21/213 (10%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q ++ +G + + +V EY G + +R R + V +
Sbjct 80 SIMQQCKSKYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTL 139
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL + +H ++ NILL G+A KL+D GV +++ V
Sbjct 140 KGLQYLHDLKKIHRDIKAGNILLNTDGIA-------KLADFGVAGQLTDTMAKRNTVIGT 192
Query 777 P-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ----H 831
P W+APE + T D W G T +E+ +G P P +
Sbjct 193 PFWMAPEVIE--EIGYDTKADIWSLGITAIEMA-EGRPPYSDIHPMRAIFMIPTKPPPTF 249
Query 832 RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ PE + CL +P +R +T LR
Sbjct 250 KKPEEWSSEFNDFIRSCLIKKPEER---KTALR 279
>sp|Q63572|TESK1_RAT Dual specificity testis-specific protein
kinase 1 OS=Rattus norvegicus OX=10116 GN=Tesk1 PE=1 SV=1
Length=628
Score = 92.0 bits (227), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 63/201 (31%), Positives = 102/201 (51%), Gaps = 16/201 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G F +V Y + +G+++ +K K P +RS +E+ ++ L H +I+++
Sbjct 58 IGAGFFSEV----YKVRHRQSGQVMVLKMNKL---PSNRSNTLREVQLMNRLRHPNILRF 110
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G C QG+ L + EY+ G+L L + L A I +G+ YLHA+ H
Sbjct 111 MGVCVHQGQ--LHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIAQGLRYLHAKGVFH 168
Query 1022 RDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVFWYAPECLKEY 1076
RDL ++N L+ D +GDFGLA+ +P E R SP +W APE L+
Sbjct 169 RDLTSKNCLVRREDGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSP-YWMAPEVLRGE 227
Query 1077 KFYYASDVWSFGVTLYELLTH 1097
+ +DV++FG+ L EL+
Sbjct 228 LYDEKADVFAFGIVLCELIAR 248
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 66/263 (25%), Positives = 104/263 (40%), Gaps = 49/263 (19%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
R GQ + + + L PS+ L LM+++ H ++ GVCV + +TEY+
Sbjct 72 RQSGQVMVLKMNKL-PSNRSNTL---REVQLMNRLRHPNILRFMGVCVHQGQLHALTEYM 127
Query 691 EHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLAR---- 744
G L+ L P++W ++ +A +A L YL K + H ++ +N L+ R
Sbjct 128 NGGTLEQLLSSPE---PLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRREDGG 184
Query 745 -------LGLAEGTSPFIKLSDPGVGLGALSREERVERIP-WLAPECLPGGANSLSTAMD 796
GLAE P GA V P W+APE L G D
Sbjct 185 FTAVVGDFGLAEKI--------PVYREGARKEPLAVVGSPYWMAPEVLRG--ELYDEKAD 234
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---------HRLPEPSCP-QLATLTS 846
+ FG L E L +R P++ ++ + + L CP L
Sbjct 235 VFAFGIVLCE--------LIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAI 286
Query 847 QCLTYEPTQRPSFRTILRDLTRL 869
C + EP+ R F I + L ++
Sbjct 287 HCCSMEPSARAPFTEITQHLEQI 309
>sp|Q2QAV0|TIO_ARATH Serine/threonine-protein kinase TIO OS=Arabidopsis
thaliana OX=3702 GN=TIO PE=1 SV=1
Length=1322
Score = 92.8 bits (229), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 67/197 (34%), Positives = 102/197 (52%), Gaps = 12/197 (6%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK-ALKADCGPQHRSGWKQEIDILRTLYHEH 958
I +GEG FG+V Y TG+ VA+K +K + +QEI+ILR L HE+
Sbjct 9 IELVGEGSFGRV----YKGRRKYTGQTVAMKFIMKQGKTDKDIHSLRQEIEILRKLKHEN 64
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQ 1017
II+ E+ E +V E+ G L + L + Q+ A+Q+ + + YLH+
Sbjct 65 IIEMLDSFENARE--FCVVTEFAQ-GELFEILEDDKCLPEEQVQAIAKQLVKALDYLHSN 121
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ +N+L+ +VK+ DFG A+A+ +R +P + APE +KE
Sbjct 122 RIIHRDMKPQNILIGAGSVVKLCDFGFARAMSTN--TVVLRSIKGTP-LYMAPELVKEQP 178
Query 1078 FYYASDVWSFGVTLYEL 1094
+ D+WS GV LYEL
Sbjct 179 YDRTVDLWSLGVILYEL 195
Score = 37.7 bits (86), Expect = 0.81, Method: Compositional matrix adjust.
Identities = 44/187 (24%), Positives = 76/187 (41%), Gaps = 20/187 (11%)
Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
E +VTE+ + G L L ++ +P +A+QL AL YL + ++H ++ +NIL
Sbjct 77 EFCVVTEFAQ-GELFEILEDDKC-LPEEQVQAIAKQLVKALDYLHSNRIIHRDMKPQNIL 134
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP----WLAPECLPGGANSLSTAMDK 797
+ G +KL D G + + I ++APE + +D
Sbjct 135 I-------GAGSVVKLCDFGFARAMSTNTVVLRSIKGTPLYMAPELVK--EQPYDRTVDL 185
Query 798 WGFGATLLEICFDGEAPLQSRSP-SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
W G L E+ + G+ P + S + H + + P+ + L EP R
Sbjct 186 WSLGVILYEL-YVGQPPFYTNSVYALIRHIVKDPVKYPDEMSTYFESFLKGLLNKEPHSR 244
Query 857 ---PSFR 860
P+ R
Sbjct 245 LTWPALR 251
>sp|P17157|PHO85_YEAST Cyclin-dependent protein kinase PHO85 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=PHO85 PE=1 SV=2
Length=305
Score = 88.6 bits (218), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 63/209 (30%), Positives = 101/209 (48%), Gaps = 20/209 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
K++ LG G + V Y N TG VA+K +K D S +EI +++ L H
Sbjct 7 FKQLEKLGNGTYATV----YKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKH 62
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFAQQICE 1009
E+I++ E L LV E++ L+ Y+ ++G L + F Q+ +
Sbjct 63 ENIVRLYDVI--HTENKLTLVFEFMD-NDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQ 119
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068
G+A+ H +HRDL +N+L++ +K+GDFGLA+A + + WY
Sbjct 120 GLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTF----SSEVVTLWYR 175
Query 1069 APECLKEYKFYYAS-DVWSFGVTLYELLT 1096
AP+ L + Y S D+WS G L E++T
Sbjct 176 APDVLMGSRTYSTSIDIWSCGCILAEMIT 204
Score = 44.7 bits (104), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 76/330 (23%), Positives = 131/330 (40%), Gaps = 66/330 (20%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDP-EEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ QL LG GT VY+G + G +E K+D E+ G + ++
Sbjct 6 QFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEE--------GTPSTAIREI--- 54
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
SLM ++ H ++ ++ V + +V E++++ R G+
Sbjct 55 -------------SLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNT 101
Query 707 PMAWKMVVAQ----QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
P ++ + + QL L++ ++H ++ +N+L+ + G +KL D G+
Sbjct 102 PRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQ-------LKLGDFGL 154
Query 763 ----GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
G+ + V + + AP+ L G+ + ST++D W G L E+ G+
Sbjct 155 ARAFGIPVNTFSSEVVTLWYRAPDVL-MGSRTYSTSIDIWSCGCILAEMI-TGKPLFPGT 212
Query 819 SPSEKEHFYQRQHRLPEPSC-PQLATLTSQCLTYEPT--QRPSFRTILRDLTR-LQPH-- 872
+ E+ P S P + L Y P QRP RDL + LQPH
Sbjct 213 NDEEQLKLIFDIMGTPNESLWPSVTKLPK----YNPNIQQRPP-----RDLRQVLQPHTK 263
Query 873 -----NLAD----VLTVNPDSPASDPTVFH 893
NL D +L +NPD S H
Sbjct 264 EPLDGNLMDFLHGLLQLNPDMRLSAKQALH 293
>sp|Q69ZA1|CDK13_MOUSE Cyclin-dependent kinase 13 OS=Mus musculus
OX=10090 GN=Cdk13 PE=1 SV=3
Length=1511
Score = 92.8 bits (229), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 68/212 (32%), Positives = 103/212 (49%), Gaps = 31/212 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958
+GEG +G+V Y + TGEMVA+K ++ D + G+ +EI ILR L H+
Sbjct 711 IGEGTYGQV----YKARDKDTGEMVALKKVRLD---NEKEGFPITAIREIKILRQLTHQS 763
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL----------FAQQIC 1008
II K D+ E +L + + +Y+ +GL + L F +Q+
Sbjct 764 IINMKEIVTDK-EDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLM 822
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK--AVPEGHEYYRVREDGDSPVF 1066
EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ + E Y
Sbjct 823 EGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYT-----NKVITL 877
Query 1067 WYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096
WY P L E ++ A DVWS G L EL T
Sbjct 878 WYRPPELLLGEERYTPAIDVWSCGCILGELFT 909
Score = 35.8 bits (81), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 57/242 (24%), Positives = 92/242 (38%), Gaps = 54/242 (22%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
VD+ +I + +G+GT VY+ R D + G+M V LK
Sbjct 702 VDKFDIIGI--IGEGTYGQVYKAR-------DKDTGEM-----------------VALKK 735
Query 644 --LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI----------MVTEYVE 691
LD + ++ Q++H + + + + + +V EY++
Sbjct 736 VRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMD 795
Query 692 HGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
H D+ E G V + + +QL L Y KN +H ++ NILL G
Sbjct 796 H---DLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQ-- 850
Query 750 GTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKWGFGATLL 805
IKL+D G+ S E R ++ W P L G + A+D W G L
Sbjct 851 -----IKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILG 905
Query 806 EI 807
E+
Sbjct 906 EL 907
>sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo
sapiens OX=9606 GN=STK10 PE=1 SV=1
Length=968
Score = 92.4 bits (228), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 60/200 (30%), Positives = 105/200 (53%), Gaps = 17/200 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+LG+G FGKV Y N TG + A K ++ + + EI+IL T H +I+K
Sbjct 41 ELGDGAFGKV----YKAKNKETGALAAAKVIETK-SEEELEDYIVEIEILATCDHPYIVK 95
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019
G G+ L +++E+ P G++ + GL Q+ + +Q+ E + +LH++
Sbjct 96 LLGAYYHDGK--LWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRI 153
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP-----ECLK 1074
IHRDL A NVL+ + +++ DFG++ + + + R+ +W AP E +K
Sbjct 154 IHRDLKAGNVLMTLEGDIRLADFGVS---AKNLKTLQKRDSFIGTPYWMAPEVVMCETMK 210
Query 1075 EYKFYYASDVWSFGVTLYEL 1094
+ + Y +D+WS G+TL E+
Sbjct 211 DTPYDYKADIWSLGITLIEM 230
Score = 42.0 bits (97), Expect = 0.039, Method: Compositional matrix adjust.
Identities = 38/133 (29%), Positives = 62/133 (47%), Gaps = 17/133 (13%)
Query 684 IMVTEYVEHGPLD-VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
IM+ E+ G +D + L +RG + VV +Q+ AL++L +K ++H ++ N+L+
Sbjct 108 IMI-EFCPGGAVDAIMLELDRG-LTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLM 165
Query 743 ARLGLAEGTSPFIKLSDPGV---GLGALSREERVERIP-WLAPE---CLPGGANSLSTAM 795
G I+L+D GV L L + + P W+APE C
Sbjct 166 TLEG-------DIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKA 218
Query 796 DKWGFGATLLEIC 808
D W G TL+E+
Sbjct 219 DIWSLGITLIEMA 231
>sp|E1BB52|CDK13_BOVIN Cyclin-dependent kinase 13 OS=Bos taurus
OX=9913 GN=CDK13 PE=3 SV=1
Length=1512
Score = 92.8 bits (229), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 68/212 (32%), Positives = 103/212 (49%), Gaps = 31/212 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958
+GEG +G+V Y + TGEMVA+K ++ D + G+ +EI ILR L H+
Sbjct 712 IGEGTYGQV----YKARDKDTGEMVALKKVRLD---NEKEGFPITAIREIKILRQLTHQS 764
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL----------FAQQIC 1008
II K D+ E +L + + +Y+ +GL + L F +Q+
Sbjct 765 IINMKEIVTDK-EDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLM 823
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK--AVPEGHEYYRVREDGDSPVF 1066
EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ + E Y
Sbjct 824 EGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYT-----NKVITL 878
Query 1067 WYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096
WY P L E ++ A DVWS G L EL T
Sbjct 879 WYRPPELLLGEERYTPAIDVWSCGCILGELFT 910
Score = 36.2 bits (82), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 57/242 (24%), Positives = 92/242 (38%), Gaps = 54/242 (22%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
VD+ +I + +G+GT VY+ R D + G+M V LK
Sbjct 703 VDKFDIIGI--IGEGTYGQVYKAR-------DKDTGEM-----------------VALKK 736
Query 644 --LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI----------MVTEYVE 691
LD + ++ Q++H + + + + + +V EY++
Sbjct 737 VRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMD 796
Query 692 HGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
H D+ E G V + + +QL L Y KN +H ++ NILL G
Sbjct 797 H---DLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQ-- 851
Query 750 GTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKWGFGATLL 805
IKL+D G+ S E R ++ W P L G + A+D W G L
Sbjct 852 -----IKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILG 906
Query 806 EI 807
E+
Sbjct 907 EL 908
>sp|Q9FN92|Y5597_ARATH Probable receptor-like protein kinase At5g59700
OS=Arabidopsis thaliana OX=3702 GN=At5g59700 PE=1 SV=1
Length=829
Score = 92.4 bits (228), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 76/230 (33%), Positives = 117/230 (51%), Gaps = 27/230 (12%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHE 957
R +G G FGKV +DGT VAVK P+ + G ++ EI++L H
Sbjct 486 RAIGVGGFGKV---YKGELHDGT--KVAVKR----ANPKSQQGLAEFRTEIEMLSQFRHR 536
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ-QICEGMA---- 1012
H++ G C++ E + LV EY+ G+L+ +L + GL L + +IC G A
Sbjct 537 HLVSLIGYCDENNE--MILVYEYMENGTLKSHL--YGSGLLSLSWKQRLEICIGSARGLH 592
Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH A+ IHRD+ + N+LLD + + K+ DFGL+K PE + + V +
Sbjct 593 YLHTGDAKPVIHRDVKSANILLDENLMAKVADFGLSKTGPEIDQTH-VSTAVKGSFGYLD 651
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
PE + + SDV+SFGV ++E+L C PT E++ +A+ M
Sbjct 652 PEYFRRQQLTEKSDVYSFGVVMFEVL--CARPVIDPTLTREMVNLAEWAM 699
Score = 47.4 bits (111), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 9/175 (5%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K +P F ++SQ H HL + G C E I+V EY+E+G L
Sbjct 506 KVAVKRANPKSQQGLAEFRTEIEMLSQFRHRHLVSLIGYCDENNEMILVYEYMENGTLKS 565
Query 698 WLRRERGHVPMAWKMVVAQQLASA--LSYL---ENKNLVHGNVCGRNILLARLGLAEGTS 752
L G + ++WK + + SA L YL + K ++H +V NILL +A+
Sbjct 566 HLYGS-GLLSLSWKQRLEICIGSARGLHYLHTGDAKPVIHRDVKSANILLDENLMAKVAD 624
Query 753 PFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+ + P + +S + +L PE L+ D + FG + E+
Sbjct 625 FGLSKTGPEIDQTHVSTAVK-GSFGYLDPEYFR--RQQLTEKSDVYSFGVVMFEV 676
>sp|Q14004|CDK13_HUMAN Cyclin-dependent kinase 13 OS=Homo sapiens
OX=9606 GN=CDK13 PE=1 SV=2
Length=1512
Score = 92.8 bits (229), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 68/212 (32%), Positives = 103/212 (49%), Gaps = 31/212 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958
+GEG +G+V Y + TGEMVA+K ++ D + G+ +EI ILR L H+
Sbjct 711 IGEGTYGQV----YKARDKDTGEMVALKKVRLD---NEKEGFPITAIREIKILRQLTHQS 763
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL----------FAQQIC 1008
II K D+ E +L + + +Y+ +GL + L F +Q+
Sbjct 764 IINMKEIVTDK-EDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLM 822
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK--AVPEGHEYYRVREDGDSPVF 1066
EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ + E Y
Sbjct 823 EGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYT-----NKVITL 877
Query 1067 WYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096
WY P L E ++ A DVWS G L EL T
Sbjct 878 WYRPPELLLGEERYTPAIDVWSCGCILGELFT 909
Score = 38.1 bits (87), Expect = 0.73, Method: Compositional matrix adjust.
Identities = 65/277 (23%), Positives = 102/277 (37%), Gaps = 68/277 (25%)
Query 549 RCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRL 608
+ C P+ GET I G R VD+ +I + +G+GT VY+ R
Sbjct 681 KICGPRYGETKEKDIDWGKRC--------------VDKFDIIGI--IGEGTYGQVYKAR- 723
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV--LDPSHHDIALAFYETASLMSQVS 666
D + G+M V LK LD + ++ Q++
Sbjct 724 ------DKDTGEM-----------------VALKKVRLDNEKEGFPITAIREIKILRQLT 760
Query 667 HTHLAFVHGVCVRGPENI----------MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA- 715
H + + + + + +V EY++H D+ E G V + +
Sbjct 761 HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDH---DLMGLLESGLVHFNENHIKSF 817
Query 716 -QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-- 772
+QL L Y KN +H ++ NILL G IKL+D G+ S E R
Sbjct 818 MRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQ-------IKLADFGLARLYSSEESRPY 870
Query 773 VERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
++ W P L G + A+D W G L E+
Sbjct 871 TNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGEL 907
>sp|Q6AWJ9|PTK7_DROME Tyrosine-protein kinase-like otk OS=Drosophila
melanogaster OX=7227 GN=otk PE=1 SV=1
Length=1033
Score = 92.4 bits (228), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 63/259 (24%), Positives = 123/259 (47%), Gaps = 31/259 (12%)
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
G ++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY
Sbjct 778 GLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPH--YMVLEYT 835
Query 982 PLGSLRDYLPRHS---------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
G L+ +L + + +Q+L A QI GM ++ + HRDLA
Sbjct 836 DWGDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLAT 895
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RN ++ ++ +VK+ L K EY++ R + P+ W APEC++E ++ SD+++
Sbjct 896 RNCVISSEFIVKVSYPALCKD-KYSREYHKHR-NTLLPIRWLAPECIQEDEYTTKSDIFA 953
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
+GV ++EL +++ P + + + Q L + + P +
Sbjct 954 YGVVVWELFNQ--ATKLPHEELTNEQVVQRSQAGSLEWS----------VAEATPDSLRE 1001
Query 1147 LMKNCWETEASFRPTFENL 1165
++ +CW + RP+F L
Sbjct 1002 ILLSCWVSNPKERPSFSQL 1020
Score = 56.6 bits (135), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 66/264 (25%), Positives = 105/264 (40%), Gaps = 44/264 (17%)
Query 634 GQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
G E V++K L+ + A F L+ +SH + + G+C + MV EY +
Sbjct 778 GLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDW 837
Query 693 GPLDVWLRRERGHVPMAWK-------------MVVAQQLASALSYLENKNLVHGNVCGRN 739
G L +L G V A + VA Q+A + + H ++ RN
Sbjct 838 GDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRN 897
Query 740 ILLARLGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLST 793
++ +S FI K+S P + SRE R I WLAPEC+ + +T
Sbjct 898 CVI--------SSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQ--EDEYTT 947
Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQH------RLPEPSCPQLATL 844
D + +G + E+ F+ L P E+ E QR + E + L +
Sbjct 948 KSDIFAYGVVVWEL-FNQATKL----PHEELTNEQVVQRSQAGSLEWSVAEATPDSLREI 1002
Query 845 TSQCLTYEPTQRPSFRTILRDLTR 868
C P +RPSF + L++
Sbjct 1003 LLSCWVSNPKERPSFSQLGAALSK 1026
>sp|Q6J9G1|STYK1_MOUSE Tyrosine-protein kinase STYK1 OS=Mus musculus
OX=10090 GN=Styk1 PE=2 SV=2
Length=429
Score = 90.5 bits (223), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 73/269 (27%), Positives = 116/269 (43%), Gaps = 34/269 (13%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
V +KAL+ G Q + I + L H+++++ +GCC ++ L +++E V G
Sbjct 149 VVLKALEDPVGLQEVQDFIGRIQFYQYLGKHKNLVQLEGCCTER--LPLYMMLEDVVPGD 206
Query 986 LRDYL--PRHSIGLAQLLLF----------AQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033
L +L R + LL+ +QI + +L +H H D+AARN+L+ +
Sbjct 207 LLSFLWTCRRDVMTMDGLLYDLTEKQIYHIGKQILLALEFLQEKHLFHGDVAARNILIQS 266
Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
D K+ GLA V H P+ W APE L D+WSFG+ LYE
Sbjct 267 DLTPKLCHLGLAYEV-HAHGAISSARSSTIPLKWLAPERLLLRPASIRGDIWSFGILLYE 325
Query 1094 LLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
++T + PPT L + L+R + + RP C +Y++MK C
Sbjct 326 MVTLGAPPYPEVPPTSIL----------------QYLQRKKIMKRPSSCSHAMYNIMKCC 369
Query 1152 WETEASFRPTFENLIPILKTVHEKYQGQA 1180
W RP L+ L+ +A
Sbjct 370 WRWSEDSRPLLGQLLQRLEAASRSADDKA 398
Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 50/165 (30%), Positives = 69/165 (42%), Gaps = 25/165 (15%)
Query 714 VAQQLASALSYLENKNLVHGNVCGRNIL--------LARLGLAEGTSPFIKLSDPGVGLG 765
+ +Q+ AL +L+ K+L HG+V RNIL L LGLA G
Sbjct 236 IGKQILLALEFLQEKHLFHGDVAARNILIQSDLTPKLCHLGLAYEVHAH----------G 285
Query 766 ALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
A+S R IP WLAPE L S+ D W FG L E+ G P P+
Sbjct 286 AIS-SARSSTIPLKWLAPERLLLRPASIRG--DIWSFGILLYEMVTLGAPPYPEVPPTSI 342
Query 824 EHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866
+ QR+ + P SC + + C + RP +L+ L
Sbjct 343 LQYLQRKKIMKRPSSCSHAMYNIMKCCWRWSEDSRPLLGQLLQRL 387
>sp|O65530|PEK14_ARATH Proline-rich receptor-like protein kinase
PERK14 OS=Arabidopsis thaliana OX=3702 GN=PERK14 PE=2 SV=1
Length=731
Score = 92.0 bits (227), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 71/201 (35%), Positives = 100/201 (50%), Gaps = 15/201 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG V G VAVK LK R ++ E+D + ++H+H++
Sbjct 395 LGEGGFGYVHKGVLK-----NGTEVAVKQLKIGSYQGERE-FQAEVDTISRVHHKHLVSL 448
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMAYLH---A 1016
G C + G+K L LV E+VP +L +L + + + L A +G+AYLH +
Sbjct 449 VGYCVN-GDKRL-LVYEFVPKDTLEFHLHENRGSVLEWEMRLRIAVGAAKGLAYLHEDCS 506
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075
IHRD+ A N+LLD+ K+ DFGLAK + + + F Y APE
Sbjct 507 PTIIHRDIKAANILLDSKFEAKVSDFGLAKFFSDTNSSFTHISTRVVGTFGYMAPEYASS 566
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
K SDV+SFGV L EL+T
Sbjct 567 GKVTDKSDVYSFGVVLLELIT 587
Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 51/187 (27%), Positives = 79/187 (42%), Gaps = 31/187 (17%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K L + F +S+V H HL + G CV G + ++V E+V L+
Sbjct 414 VAVKQLKIGSYQGEREFQAEVDTISRVHHKHLVSLVGYCVNGDKRLLVYEFVPKDTLEFH 473
Query 699 LRRERGHVPMAWKM--VVAQQLASALSYLE---NKNLVHGNVCGRNILL--------ARL 745
L RG V + W+M +A A L+YL + ++H ++ NILL +
Sbjct 474 LHENRGSV-LEWEMRLRIAVGAAKGLAYLHEDCSPTIIHRDIKAANILLDSKFEAKVSDF 532
Query 746 GLA----EGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
GLA + S F +S VG ++APE G ++ D + FG
Sbjct 533 GLAKFFSDTNSSFTHISTRVVGT-----------FGYMAPEYASSG--KVTDKSDVYSFG 579
Query 802 ATLLEIC 808
LLE+
Sbjct 580 VVLLELI 586
>sp|B4QC63|PTK7_DROSI Tyrosine-protein kinase-like otk OS=Drosophila
simulans OX=7240 GN=otk PE=3 SV=1
Length=1029
Score = 92.4 bits (228), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 63/259 (24%), Positives = 123/259 (47%), Gaps = 31/259 (12%)
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
G ++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY
Sbjct 774 GLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPH--YMVLEYT 831
Query 982 PLGSLRDYLPRHS---------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
G L+ +L + + +Q+L A QI GM ++ + HRDLA
Sbjct 832 DWGDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLAT 891
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RN ++ ++ +VK+ L K EY++ R + P+ W APEC++E ++ SD+++
Sbjct 892 RNCVISSEFIVKVSYPALCKD-KYSREYHKHR-NTLLPIRWLAPECIQEDEYTTKSDIFA 949
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
+GV ++EL +++ P + + + Q L + + P +
Sbjct 950 YGVVVWELFNQ--ATKLPHEELTNEQVVQRSQAGSLEWS----------VAEATPDSLRE 997
Query 1147 LMKNCWETEASFRPTFENL 1165
++ +CW + RP+F L
Sbjct 998 ILLSCWVSNPKERPSFSQL 1016
Score = 56.6 bits (135), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 66/264 (25%), Positives = 105/264 (40%), Gaps = 44/264 (17%)
Query 634 GQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
G E V++K L+ + A F L+ +SH + + G+C + MV EY +
Sbjct 774 GLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDW 833
Query 693 GPLDVWLRRERGHVPMAWK-------------MVVAQQLASALSYLENKNLVHGNVCGRN 739
G L +L G V A + VA Q+A + + H ++ RN
Sbjct 834 GDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRN 893
Query 740 ILLARLGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLST 793
++ +S FI K+S P + SRE R I WLAPEC+ + +T
Sbjct 894 CVI--------SSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQ--EDEYTT 943
Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQH------RLPEPSCPQLATL 844
D + +G + E+ F+ L P E+ E QR + E + L +
Sbjct 944 KSDIFAYGVVVWEL-FNQATKL----PHEELTNEQVVQRSQAGSLEWSVAEATPDSLREI 998
Query 845 TSQCLTYEPTQRPSFRTILRDLTR 868
C P +RPSF + L++
Sbjct 999 LLSCWVSNPKERPSFSQLGAALSK 1022
>sp|Q9FID8|Y5900_ARATH Putative receptor-like protein kinase At5g39000
OS=Arabidopsis thaliana OX=3702 GN=At5g39000 PE=3 SV=1
Length=873
Score = 92.4 bits (228), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 66/202 (33%), Positives = 98/202 (49%), Gaps = 16/202 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V Y DG +VAVK L+ Q ++ E+++L L H H++
Sbjct 524 IGVGGFGSV----YKGQIDGGATLVAVKRLEITSN-QGAKEFETELEMLSKLRHVHLVSL 578
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ--QIC----EGMAYLHA 1016
G C++ E + LV EY+P G+L+D+L R L + + +IC G+ YLH
Sbjct 579 IGYCDEDNE--MVLVYEYMPHGTLKDHLFRRDKTSDPPLSWKRRLEICIGAARGLQYLHT 636
Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRD+ N+LLD + + K+ DFGL++ P V + PE
Sbjct 637 GAKYTIIHRDIKTTNILLDENFVTKVSDFGLSRVGPTSASQTHVSTVVKGTFGYLDPEYY 696
Query 1074 KEYKFYYASDVWSFGVTLYELL 1095
+ SDV+SFGV L E+L
Sbjct 697 RRQVLTEKSDVYSFGVVLLEVL 718
Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 63/240 (26%), Positives = 102/240 (43%), Gaps = 36/240 (15%)
Query 601 TNVYEGRL--RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYET 658
TN +E +L V G G +G++D G V +K L+ + + A F
Sbjct 515 TNDFEDKLIIGVGGFGSVYKGQID-----------GGATLVAVKRLEITSNQGAKEFETE 563
Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRER-GHVPMAWK--MVV 714
++S++ H HL + G C E ++V EY+ HG L D RR++ P++WK + +
Sbjct 564 LEMLSKLRHVHLVSLIGYCDEDNEMVLVYEYMPHGTLKDHLFRRDKTSDPPLSWKRRLEI 623
Query 715 AQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG---VGLGALS 768
A L YL ++H ++ NILL + K+SD G VG + S
Sbjct 624 CIGAARGLQYLHTGAKYTIIHRDIKTTNILLDE-------NFVTKVSDFGLSRVGPTSAS 676
Query 769 REERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ + +L PE L+ D + FG LLE+ +QS P + +
Sbjct 677 QTHVSTVVKGTFGYLDPEYYR--RQVLTEKSDVYSFGVVLLEVLCCRPIRMQSVPPEQAD 734
>sp|Q0KHQ5|TAO_DROME Serine/threonine-protein kinase Tao OS=Drosophila
melanogaster OX=7227 GN=Tao PE=1 SV=1
Length=1039
Score = 92.4 bits (228), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 72/211 (34%), Positives = 110/211 (52%), Gaps = 27/211 (13%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDI 950
++ + +R++G G FG V Y + T E+VA+K + + G Q + W+ +EI
Sbjct 24 EKIFEDLREIGHGSFGAV----YYARCNLTREIVAIKKM-SYTGKQSQEKWQDILKEIRF 78
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC-- 1008
LR L H + I+YKGC E + LVMEY +GS D + H L + + A IC
Sbjct 79 LRQLNHPNTIEYKGCY--LRESTAWLVMEYC-VGSASDIIEVHKKPLHEDEIAA--ICLG 133
Query 1009 --EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G++YLH+ IHRD+ A N+LL ++ +VK+ DFG A + + +P +
Sbjct 134 VLSGLSYLHSLGRIHRDIKAGNILLTDNGVVKLADFGSAAIKCPANSFV------GTP-Y 186
Query 1067 WYAPE---CLKEYKFYYASDVWSFGVTLYEL 1094
W APE + E ++ DVWS G+T EL
Sbjct 187 WMAPEVILAMDEGQYDGKVDVWSLGITCIEL 217
Score = 36.6 bits (83), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 46/190 (24%), Positives = 70/190 (37%), Gaps = 20/190 (11%)
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL 779
S LSYL + +H ++ NILL G+ +KL+D G V W+
Sbjct 136 SGLSYLHSLGRIHRDIKAGNILLTDNGV-------VKLADFGSAAIKCPANSFVGTPYWM 188
Query 780 APEC-LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838
APE L +D W G T +E+ + S H Q + P+
Sbjct 189 APEVILAMDEGQYDGKVDVWSLGITCIELAERKPPYFNMNAMSALYHIAQNE----SPTL 244
Query 839 PQ------LATLTSQCLTYEPTQRPSFRTILRD--LTRLQPHNLADVLTVNPDSPASDPT 890
P+ + CL P +RPS +L +TR + + L S +
Sbjct 245 PKNDWSDAFCSFVELCLKKMPAERPSSAKLLTHAYVTRPRSDTVLLELIARTKSAVRELD 304
Query 891 VFHKRYLKKI 900
+ R +KKI
Sbjct 305 NLNYRKMKKI 314
>sp|P48963|CDK2_MESAU Cyclin-dependent kinase 2 OS=Mesocricetus
auratus OX=10036 GN=CDK2 PE=2 SV=1
Length=298
Score = 88.2 bits (217), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 61/203 (30%), Positives = 100/203 (49%), Gaps = 11/203 (5%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955
+K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ L
Sbjct 4 FQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH 1015
H +I+K + + L + + L D I L + + Q+ +G+A+ H
Sbjct 60 HPNIVKLLDVIHTENKLYLVFELLHQDLKKFMDASAVTGIPLPLIKSYLFQLLQGLAFCH 119
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074
+ +HRDL +N+L++ + +K+ DFGLA+A Y + WY APE L
Sbjct 120 SHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTY----THEVVTLWYRAPEILL 175
Query 1075 EYKFY-YASDVWSFGVTLYELLT 1096
K+Y A D+WS G E++T
Sbjct 176 GCKYYSTAVDIWSLGCIFAEMVT 198
Score = 37.0 bits (84), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 49/194 (25%), Positives = 83/194 (43%), Gaps = 46/194 (24%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREER 772
QL L++ + ++H ++ +N+L+ AEG+ IKL+D G+ G+ +
Sbjct 110 QLLQGLAFCHSHRVLHRDLKPQNLLIN----AEGS---IKLADFGLARAFGVPVRTYTHE 162
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQS------RSPS 821
V + + APE L G STA+D W G E+ F G++ + +
Sbjct 163 VVTLWYRAPEIL-LGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGT 221
Query 822 EKEHFYQRQHRLPE--PSCPQLA----------------TLTSQCLTYEPTQRPSFRTIL 863
E + +P+ PS P+ A +L SQ L Y+P +R S + L
Sbjct 222 PDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAAL 281
Query 864 -----RDLTRLQPH 872
+D+T+ PH
Sbjct 282 AHPFFQDVTKPVPH 295
>sp|O19004|ARAF_PIG Serine/threonine-protein kinase A-Raf OS=Sus
scrofa OX=9823 GN=ARAF PE=2 SV=1
Length=606
Score = 91.7 bits (226), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 74/261 (28%), Positives = 115/261 (44%), Gaps = 42/261 (16%)
Query 927 VAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
VAVK LK A + +K E+ +LR H +I+ + G G ++ ++ S
Sbjct 333 VAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG---FAIITQWCEGSS 389
Query 986 LRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
L +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L VKIGDFG
Sbjct 390 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFG 449
Query 1044 LAKAVPEGHEYYRVREDGDSP-------VFWYAPECLKEYK---FYYASDVWSFGVTLYE 1093
LA + R G P V W A E ++ + + SDV+++GV LYE
Sbjct 450 LATV--------KTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYE 501
Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK----CPCEVYHLMK 1149
L+T L I + ++ RG P K CP + L+
Sbjct 502 LMTGS----------LPYSHIGSRDQIIF----MVGRGYLSPDLSKISSNCPKAMRRLLS 547
Query 1150 NCWETEASFRPTFENLIPILK 1170
+C + + RP F ++ ++
Sbjct 548 DCLKFQREERPLFPQILATIE 568
Score = 59.7 bits (143), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 68/255 (27%), Positives = 106/255 (42%), Gaps = 24/255 (9%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
GR G VLKV P+ A AF ++ + H ++ G R P ++T++
Sbjct 327 GRWHGDVAVKVLKVAQPTAEQ-AQAFKNEMQVLRKTRHVNILLFMGFMTR-PGFAIITQW 384
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
E L L M + VA+Q A + YL KN++H ++ NI L E
Sbjct 385 CEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIF-----LHE 439
Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802
G + +K+ D G+ GA E+ + W+A E + N S D + +G
Sbjct 440 GLT--VKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 497
Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855
L E+ G P ++ F R + P+ S CP+ + L S CL ++ +
Sbjct 498 VLYEL-MTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREE 556
Query 856 RPSFRTILRDLTRLQ 870
RP F IL + LQ
Sbjct 557 RPLFPQILATIELLQ 571
>sp|Q9C660|PEK10_ARATH Proline-rich receptor-like protein kinase
PERK10 OS=Arabidopsis thaliana OX=3702 GN=PERK10 PE=1 SV=2
Length=762
Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 72/212 (34%), Positives = 102/212 (48%), Gaps = 25/212 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG+V +VAVK LK G R +K E+D + ++H +++
Sbjct 436 LGEGGFGRVYKGVLP-----DERVVAVKQLKIGGGQGDRE-FKAEVDTISRVHHRNLLSM 489
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL-----AQLLLFAQQICEGMAYLHAQ 1017
G C + + L+ +YVP +L Y H+ G A + A G+AYLH
Sbjct 490 VGYCISENRR--LLIYDYVPNNNL--YFHLHAAGTPGLDWATRVKIAAGAARGLAYLHED 545
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECL 1073
IHRD+ + N+LL+N+ + DFGLAK + + + R G F Y APE
Sbjct 546 CHPRIIHRDIKSSNILLENNFHALVSDFGLAKLALDCNTHITTRVMG---TFGYMAPEYA 602
Query 1074 KEYKFYYASDVWSFGVTLYELLTH---CDSSQ 1102
K SDV+SFGV L EL+T D+SQ
Sbjct 603 SSGKLTEKSDVFSFGVVLLELITGRKPVDASQ 634
Score = 35.8 bits (81), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 44/184 (24%), Positives = 74/184 (40%), Gaps = 21/184 (11%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F +S+V H +L + G C+ +++ +YV + L L G + W ++
Sbjct 471 FKAEVDTISRVHHRNLLSMVGYCISENRRLLIYDYVPNNNLYFHL-HAAGTPGLDWATRV 529
Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+A A L+YL ++H ++ NILL A +SD G+ AL
Sbjct 530 KIAAGAARGLAYLHEDCHPRIIHRDIKSSNILLENNFHA-------LVSDFGLAKLALDC 582
Query 770 EERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++APE G L+ D + FG LLE+ G P+ + P E
Sbjct 583 NTHITTRVMGTFGYMAPEYASSG--KLTEKSDVFSFGVVLLEL-ITGRKPVDASQPLGDE 639
Query 825 HFYQ 828
+
Sbjct 640 SLVE 643
>sp|Q5ZJK4|STK4_CHICK Serine/threonine-protein kinase 4 OS=Gallus
gallus OX=9031 GN=STK4 PE=2 SV=1
Length=486
Score = 90.9 bits (224), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 58/197 (29%), Positives = 96/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V + + TG++VA+K + + Q +EI I++ H+
Sbjct 32 LEKLGEGSYGSV----FKAIHKETGQVVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 84
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 85 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEEEIATIVQSTLKGLEYLHFM 142
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW AP ++E
Sbjct 143 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPGVIQEIG 199
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 200 YNCVADIWSLGITAIEM 216
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 51/214 (24%), Positives = 79/214 (37%), Gaps = 20/214 (9%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q H+ +G + + +V EY G + +R + + Q
Sbjct 74 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEEEIATIVQSTL 133
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL +H ++ NILL G A KL+D GV +++ V
Sbjct 134 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 186
Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830
P W+AP + G N ++ D W G T +E+ +G+ P P
Sbjct 187 PFWMAPGVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 242
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R PE QCL P QR + +L+
Sbjct 243 FRKPELWSDAFTDFVKQCLVKSPEQRATAIQLLQ 276
>sp|Q8QFP8|LIMK1_CHICK LIM domain kinase 1 OS=Gallus gallus OX=9031
GN=LIMK1 PE=1 SV=1
Length=662
Score = 91.7 bits (226), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 80/289 (28%), Positives = 129/289 (45%), Gaps = 45/289 (16%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+ T+ TGE++ +K L R+ K E+ ++R L H +++K+
Sbjct 352 LGKGCFGQA----IKVTHRETGEVMVMKELIRFDEETQRTFLK-EVKVMRCLEHPNVLKF 406
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYI 1020
G EK L + EY+ G+LR + +Q + FA+ I GMAYLH+ + I
Sbjct 407 IGVL--YKEKRLNFITEYIKGGTLRGLIKSMDSHYPWSQRVSFAKDIAAGMAYLHSMNII 464
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAV---------------PEGHEYYRVREDGDSPV 1065
HRDL + N L+ ++ V + DFGLA+ + P+ + Y V +
Sbjct 465 HRDLNSHNCLVRENKSVVVADFGLARLMVDEKNQPEHLQNLKKPDRKKRYTVVGNP---- 520
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELL--THCDSSQSPPTKFLELIGIAQGQMTVLR 1123
+W APE + + D++SFG+ L E++ D P T L
Sbjct 521 YWMAPEMINGRSYDEKVDIFSFGIVLCEIIGRVSADPDYLPRTTDFG-----------LN 569
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ LER P CP + + C + + RP+F L L+T+
Sbjct 570 VRGFLERY----CPPACPPSFFPIAACCCDLDPEKRPSFSKLEQWLETL 614
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 59/256 (23%), Positives = 105/256 (41%), Gaps = 32/256 (13%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+V+K L + F + +M + H ++ GV + +TEY++ G L
Sbjct 372 MVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKEKRLNFITEYIKGGTLRGL 431
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL-------------LARL 745
++ H P + ++ A+ +A+ ++YL + N++H ++ N L LARL
Sbjct 432 IKSMDSHYPWSQRVSFAKDIAAGMAYLHSMNIIHRDLNSHNCLVRENKSVVVADFGLARL 491
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAMDKWG 799
+ E P L L + +R +R W+APE + G S +D +
Sbjct 492 MVDEKNQP--------EHLQNLKKPDRKKRYTVVGNPYWMAPEMING--RSYDEKVDIFS 541
Query 800 FGATLLEIC--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSC-PQLATLTSQCLTYEPTQR 856
FG L EI + R+ + R P+C P + + C +P +R
Sbjct 542 FGIVLCEIIGRVSADPDYLPRTTDFGLNVRGFLERYCPPACPPSFFPIAACCCDLDPEKR 601
Query 857 PSFRTILRDLTRLQPH 872
PSF + + L L+ H
Sbjct 602 PSFSKLEQWLETLRMH 617
>sp|P52304|POLO_DROME Serine/threonine-protein kinase polo OS=Drosophila
melanogaster OX=7227 GN=polo PE=1 SV=2
Length=576
Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 68/217 (31%), Positives = 108/217 (50%), Gaps = 12/217 (6%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
D P + ++ K++R G+G F K CY+ + T ++ A K + +H
Sbjct 11 DIPDRLVDINQRKTYKRMRFFGKGGFAK----CYEIIDVETDDVFAGKIVSKKLMIKHNQ 66
Query 943 GWK--QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQ 999
K QEI I R+L H +I+K+ ED +++ +V+E S+ + + R SI +
Sbjct 67 KEKTAQEITIHRSLNHPNIVKFHNYFEDS--QNIYIVLELCKKRSMMELHKRRKSITEFE 124
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
+ QI +G+ YLH IHRDL N+ L++ VKIGDFGLA + +E R +
Sbjct 125 CRYYIYQIIQGVKYLHDNRIIHRDLKLGNLFLNDLLHVKIGDFGLATRIE--YEGERKKT 182
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+P + APE L + + D+WS G +Y LL
Sbjct 183 LCGTPN-YIAPEILTKKGHSFEVDIWSIGCVMYTLLV 218
>sp|Q8BTW9|PAK4_MOUSE Serine/threonine-protein kinase PAK 4 OS=Mus
musculus OX=10090 GN=Pak4 PE=1 SV=1
Length=593
Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 71/237 (30%), Positives = 111/237 (47%), Gaps = 21/237 (9%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
L V+P P S YL +GEG G V + T +G++VAVK K D
Sbjct 312 LVVDPGDPRS--------YLDNFIKIGEGSTGIVCIA----TVRSSGKLVAVK--KMDLR 357
Query 938 PQHRSGWK-QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996
Q R E+ I+R HE++++ E L +VME++ G+L D + +
Sbjct 358 KQQRRELLFNEVVIMRDYRHENVVEMYNSYLVGDE--LWVVMEFLEGGALTDIVTHTRMN 415
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
Q+ + + +A LHAQ IHRD+ + ++LL +D VK+ DFG V E R
Sbjct 416 EEQIAAVCLAVLQALAVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQV--SKEVPR 473
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELI 1112
+ +P +W APE + + D+WS GV + E++ PP K +++I
Sbjct 474 RKSLVGTP-YWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMI 529
>sp|P51956|NEK3_HUMAN Serine/threonine-protein kinase Nek3 OS=Homo
sapiens OX=9606 GN=NEK3 PE=1 SV=2
Length=506
Score = 90.9 bits (224), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 70/270 (26%), Positives = 127/270 (47%), Gaps = 27/270 (10%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+R +GEG FG+ L ++ +N +M A+K ++ + ++E +L + H +I
Sbjct 7 LRMIGEGSFGRALLVQHESSN----QMFAMKEIRLPKSFSNTQNSRKEAVLLAKMKHPNI 62
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLHA 1016
+ +K E +G L +VMEY G L + + L +L + Q+C G+ ++H
Sbjct 63 VAFKESFEAEGH--LYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHK 120
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ +HRD+ ++N+ L + VK+GDFG A+ + + +P ++ PE +
Sbjct 121 KRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACTY--VGTP-YYVPPEIWENL 177
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+ SD+WS G LYEL T Q+ K L ++ + QG ++ P
Sbjct 178 PYNNKSDIWSLGCILYELCTLKHPFQANSWKNL-ILKVCQGCIS--------------PL 222
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
P E+ L+K ++ S RP+ L+
Sbjct 223 PSHYSYELQFLVKQMFKRNPSHRPSATTLL 252
>sp|Q63699|CDK2_RAT Cyclin-dependent kinase 2 OS=Rattus norvegicus
OX=10116 GN=Cdk2 PE=1 SV=1
Length=298
Score = 88.2 bits (217), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 64/205 (31%), Positives = 102/205 (50%), Gaps = 15/205 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955
+K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ L
Sbjct 4 FQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYV--PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013
H +I+K E L LV E++ L D + L + + Q+ +G+A+
Sbjct 60 HPNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGLPLPLIKSYLFQLLQGLAF 117
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072
H+ +HRDL +N+L++ + +K+ DFGLA+A Y + WY APE
Sbjct 118 CHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTY----THEVVTLWYRAPEI 173
Query 1073 LKEYKFY-YASDVWSFGVTLYELLT 1096
L K+Y A D+WS G E++T
Sbjct 174 LLGCKYYSTAVDIWSLGCIFAEMVT 198
Score = 37.0 bits (84), Expect = 0.99, Method: Compositional matrix adjust.
Identities = 49/194 (25%), Positives = 83/194 (43%), Gaps = 46/194 (24%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREER 772
QL L++ + ++H ++ +N+L+ AEG+ IKL+D G+ G+ +
Sbjct 110 QLLQGLAFCHSHRVLHRDLKPQNLLIN----AEGS---IKLADFGLARAFGVPVRTYTHE 162
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQS------RSPS 821
V + + APE L G STA+D W G E+ F G++ + +
Sbjct 163 VVTLWYRAPEIL-LGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGT 221
Query 822 EKEHFYQRQHRLPE--PSCPQLA----------------TLTSQCLTYEPTQRPSFRTIL 863
E + +P+ PS P+ A +L SQ L Y+P +R S + L
Sbjct 222 PDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAAL 281
Query 864 -----RDLTRLQPH 872
+D+T+ PH
Sbjct 282 AHPFFQDVTKPVPH 295
>sp|B4P5Q9|PTK7_DROYA Tyrosine-protein kinase-like otk OS=Drosophila
yakuba OX=7245 GN=otk PE=3 SV=1
Length=1033
Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 63/259 (24%), Positives = 122/259 (47%), Gaps = 31/259 (12%)
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
G ++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY
Sbjct 778 GLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPH--YMVLEYT 835
Query 982 PLGSLRDYLPRHS---------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
G L+ +L + + +Q+L A QI GM ++ + HRDLA
Sbjct 836 DWGDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLAT 895
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RN ++ ++ +VK+ L K EY++ R + P+ W APEC++E ++ SD+++
Sbjct 896 RNCVISSEFIVKVSYPALCKD-KYSREYHKHR-NTLLPIRWLAPECIQEDEYTTKSDIFA 953
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
+GV ++EL +++ P + + + Q L + + P +
Sbjct 954 YGVVVWELFNQ--ATKLPHEELTNEQVVQRSQAGSLEWS----------VAESTPDSLRE 1001
Query 1147 LMKNCWETEASFRPTFENL 1165
++ +CW RP+F L
Sbjct 1002 ILLSCWVANPKERPSFSQL 1020
Score = 56.6 bits (135), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 66/264 (25%), Positives = 105/264 (40%), Gaps = 44/264 (17%)
Query 634 GQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
G E V++K L+ + A F L+ +SH + + G+C + MV EY +
Sbjct 778 GLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDW 837
Query 693 GPLDVWLRRERGHVPMAWK-------------MVVAQQLASALSYLENKNLVHGNVCGRN 739
G L +L G V A + VA Q+A + + H ++ RN
Sbjct 838 GDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRN 897
Query 740 ILLARLGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLST 793
++ +S FI K+S P + SRE R I WLAPEC+ + +T
Sbjct 898 CVI--------SSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQ--EDEYTT 947
Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQH------RLPEPSCPQLATL 844
D + +G + E+ F+ L P E+ E QR + E + L +
Sbjct 948 KSDIFAYGVVVWEL-FNQATKL----PHEELTNEQVVQRSQAGSLEWSVAESTPDSLREI 1002
Query 845 TSQCLTYEPTQRPSFRTILRDLTR 868
C P +RPSF + L++
Sbjct 1003 LLSCWVANPKERPSFSQLGAALSK 1026
>sp|Q54RV3|PAKG_DICDI Serine/threonine-protein kinase pakG OS=Dictyostelium
discoideum OX=44689 GN=pakG PE=3 SV=1
Length=1179
Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 60/197 (30%), Positives = 103/197 (52%), Gaps = 20/197 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G +G V Y + T ++A+K++ + ++EI IL+ ++I+ Y
Sbjct 145 LGTGSYGTV----YKAIHKDTNFVLAIKSIPI----KESEEIEKEISILKKCKSQNIVSY 196
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G + QG+ +L ++MEY S+RD L S+ Q+ + QQ +G+ YLH + I
Sbjct 197 FGSGQ-QGD-NLWILMEYCSANSIRDMLELTEKSLTEKQISVILQQALKGLHYLHQSNII 254
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---FWYAPECLKEYK 1077
HRD+ A N+L++ D +VK+ DFG++ + + +R + V W APE +K
Sbjct 255 HRDIKAANILINEDAIVKLADFGVSSQLEDS-----LRGEASQLVGTPLWMAPEIIKRQN 309
Query 1078 FYYASDVWSFGVTLYEL 1094
+ D+WS G+T E+
Sbjct 310 YNNKCDIWSLGITAIEM 326
Score = 38.1 bits (87), Expect = 0.74, Method: Compositional matrix adjust.
Identities = 40/158 (25%), Positives = 65/158 (41%), Gaps = 25/158 (16%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSRE 770
V+ QQ L YL N++H ++ NIL+ + +KL+D GV L R
Sbjct 236 VILQQALKGLHYLHQSNIIHRDIKAANILINEDAI-------VKLADFGVSSQLEDSLRG 288
Query 771 ERVERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
E + + W+APE + + + D W G T +E+ + PL + P+
Sbjct 289 EASQLVGTPLWMAPEII--KRQNYNNKCDIWSLGITAIEMA-ESFPPLYTMPPTRAMLMI 345
Query 828 QRQHRLPEPS-------CPQLATLTSQCLTYEPTQRPS 858
+ P P+ +L QC +P +RPS
Sbjct 346 PNK---PPPTLSKPHHFSKELNDFIGQCCQKDPEKRPS 380
>sp|Q86YV6|MYLK4_HUMAN Myosin light chain kinase family member
4 OS=Homo sapiens OX=9606 GN=MYLK4 PE=1 SV=2
Length=388
Score = 89.4 bits (220), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 69/208 (33%), Positives = 105/208 (50%), Gaps = 23/208 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+ K LG G FG+V + TG +A K +K G + + K EI ++ L H
Sbjct 106 VSKTEILGGGRFGQV----HKCEETATGLKLAAKIIKTR-GMKDKEEVKNEISVMNQLDH 160
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYL 1014
++I+ E + + + LVMEYV G L D + S L +L +LF +QICEG+ ++
Sbjct 161 ANLIQLYDAFESKND--IVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHM 218
Query 1015 HAQHYIHRDLAARNVLLDN--DRLVKIGDFGLAKAVPEGHEYYRVRE----DGDSPVFWY 1068
H + +H DL N+L N + +KI DFGLA+ Y+ RE + +P F
Sbjct 219 HQMYILHLDLKPENILCVNRDAKQIKIIDFGLARR-------YKPREKLKVNFGTPEF-L 270
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLT 1096
APE + + +D+WS GV Y LL+
Sbjct 271 APEVVNYDFVSFPTDMWSVGVIAYMLLS 298
>sp|Q2RA93|WNK6_ORYSJ Probable serine/threonine-protein kinase
WNK6 OS=Oryza sativa subsp. japonica OX=39947 GN=WNK6 PE=2
SV=1
Length=439
Score = 90.1 bits (222), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 72/248 (29%), Positives = 118/248 (48%), Gaps = 23/248 (9%)
Query 876 DVLTVNPDSPASDPTVFHK----RYLKKIRDLGEGHFGKVSLYCYDPTNDGT----GEMV 927
DV P+ P DP V RYL+ +G G K +D DG G++
Sbjct 10 DVADEQPEPPDEDPDVAEADPTGRYLRYREIIGSGS-SKTVYKAFDAV-DGIEVAWGKVE 67
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
+ + R + EI +L++L H+HI+K D +++ +V E G+LR
Sbjct 68 INERIMGSSKELQR--LRTEIQLLKSLQHKHILKLYASWVDTNRRTVNIVTELFTSGNLR 125
Query 988 DYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFG 1043
+Y +H + + + +A+QI G+ YLH+Q IHRDL N+ ++ N VKIGDFG
Sbjct 126 EYRTKHKKVDMKAMRRWAKQILTGLEYLHSQKPPIIHRDLKCDNIFINGNHGKVKIGDFG 185
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
LA + + R + + APE E + D++SFG+ + E++T C+ S
Sbjct 186 LAMVMQQ-----RKTRSIQGTIEFMAPELFGE-NYNELVDIYSFGMCMLEMVT-CECPYS 238
Query 1104 PPTKFLEL 1111
F+++
Sbjct 239 ECKGFIQI 246
>sp|Q8IVT5|KSR1_HUMAN Kinase suppressor of Ras 1 OS=Homo sapiens
OX=9606 GN=KSR1 PE=1 SV=3
Length=923
Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 77/287 (27%), Positives = 137/287 (48%), Gaps = 42/287 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ-HRSGWKQEIDILRTLYHEHIIK 961
+G+G +G+V + GE VA++ L+ D Q H +K+E+ R HE+++
Sbjct 619 IGQGRWGRVHRGRWH------GE-VAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVL 671
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G C + L ++ + +L ++ P+ S+ + + AQ+I +GM YLHA+
Sbjct 672 FMGACMNPPH--LAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGI 729
Query 1020 IHRDLAARNVLLDNDRLV--KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+H+DL ++NV DN ++V G FG++ V EG +++ D + + APE ++E
Sbjct 730 VHKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDW-LCYLAPEIVREMT 788
Query 1078 ---------FYYASDVWSFGVTLYELLTHCD---SSQSPPTKFLELIGIAQGQMTVLRLT 1125
F A+DV++FG YEL D +Q+ + IG +G VL
Sbjct 789 PGKDEDQLPFSKAADVYAFGTVWYELQAR-DWPLKNQAAEASIWQ-IGSGEGMKRVLTSV 846
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
L + EV ++ CW + RP+F L+ +L+ +
Sbjct 847 SLGK-------------EVSEILSACWAFDLQERPSFSLLMDMLEKL 880
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 54/261 (21%), Positives = 110/261 (42%), Gaps = 34/261 (13%)
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
E+ + L +D + D F + Q H ++ G C+ P ++T + + L
Sbjct 635 EVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTL 694
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
++R + + + +AQ++ + YL K +VH ++ +N+ + +
Sbjct 695 HSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFY--------DNGKV 746
Query 756 KLSDPGV-GLGALSREERVER--------IPWLAPECL----PGGANS---LSTAMDKWG 799
++D G+ G+ + RE R E + +LAPE + PG S A D +
Sbjct 747 VITDFGLFGISGVVREGRRENQLKLSHDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYA 806
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQ------RQHRLPEPSC-PQLATLTSQCLTYE 852
FG E+ + PL+++ + + +Q + L S +++ + S C ++
Sbjct 807 FGTVWYELQAR-DWPLKNQ--AAEASIWQIGSGEGMKRVLTSVSLGKEVSEILSACWAFD 863
Query 853 PTQRPSFRTILRDLTRLQPHN 873
+RPSF ++ L +L N
Sbjct 864 LQERPSFSLLMDMLEKLPKLN 884
>sp|Q6FKD4|PHO85_CANGA Negative regulator of the PHO system OS=Candida
glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761
/ NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=PHO85 PE=3 SV=1
Length=302
Score = 87.8 bits (216), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 63/209 (30%), Positives = 100/209 (48%), Gaps = 20/209 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
K++ LG G + V Y N TG VA+K +K D S +EI +++ L H
Sbjct 6 FKQLEKLGNGTYATV----YKGLNKSTGVYVALKEVKLDSEEGTPSTAIREISLMKELKH 61
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFAQQICE 1009
++I++ E L LV EY+ L+ Y+ ++G + + F Q+ E
Sbjct 62 DNIVRLYDVI--HTENKLTLVFEYMD-NDLKKYMDSRTVGNAPRGLEMNLVKYFQWQLLE 118
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068
G+A+ H +HRDL +N+L+ +K+GDFGLA+A + + WY
Sbjct 119 GLAFCHENKILHRDLKPQNLLITKRGQLKLGDFGLARAFGIPVNTF----SSEVVTLWYR 174
Query 1069 APECLKEYKFYYAS-DVWSFGVTLYELLT 1096
AP+ L + Y S D+WS G L E++T
Sbjct 175 APDVLMGSRTYSTSIDIWSCGCILAEMIT 203
Score = 46.2 bits (108), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 71/319 (22%), Positives = 128/319 (40%), Gaps = 64/319 (20%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--VLD 645
+ QL LG GT VY+G + G + V LK LD
Sbjct 5 QFKQLEKLGNGTYATVYKGLNKSTG------------------------VYVALKEVKLD 40
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ A E SLM ++ H ++ ++ V + +V EY+++ R G+
Sbjct 41 SEEGTPSTAIREI-SLMKELKHDNIVRLYDVIHTENKLTLVFEYMDNDLKKYMDSRTVGN 99
Query 706 VPMAWKMVVAQ----QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
P +M + + QL L++ ++H ++ +N+L+ + G +KL D G
Sbjct 100 APRGLEMNLVKYFQWQLLEGLAFCHENKILHRDLKPQNLLITKRGQ-------LKLGDFG 152
Query 762 V----GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ G+ + V + + AP+ L G+ + ST++D W G L E+ +
Sbjct 153 LARAFGIPVNTFSSEVVTLWYRAPDVL-MGSRTYSTSIDIWSCGCILAEMITGKPLFPGT 211
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL-RDL-TRLQPH--- 872
+ + + + E + P + +L P P+F+ L +DL LQP+
Sbjct 212 NDEEQLKLIFDKMGTPNETTWPGVTSL--------PKYNPNFQQRLPKDLKAELQPYVKE 263
Query 873 ----NLAD----VLTVNPD 883
N+ D +L +NPD
Sbjct 264 PLDDNVIDLLHGLLQLNPD 282
>sp|Q61G93|ROL3_CAEBR Protein roller-3 OS=Caenorhabditis briggsae
OX=6238 GN=rol-3 PE=3 SV=3
Length=2439
Score = 92.4 bits (228), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 74/265 (28%), Positives = 123/265 (46%), Gaps = 30/265 (11%)
Query 927 VAVKALKADCGPQH--RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
VAVK L+ R + +E +L L H +I+K G C G+ +++EY+ G
Sbjct 1960 VAVKQLRPKSANHDFDRMMFMKEAILLNNLDH-NIVKELGVCVSPGQG--LILLEYMEGG 2016
Query 985 SLRDYLPRHS--------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036
+L ++L + + LL + I GM YL ++H++L+AR LL
Sbjct 2017 NLLNFLRESAPSEMQASELSTRDLLAISVDIARGMNYLERLPHVHKNLSARKCLLSGRPG 2076
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
V + G+ +A+ +G E RV + V W APE K+ F SDVW++GV LYE+ +
Sbjct 2077 VAKLEMGMPRALSKG-EINRVDLESMQSVKWMAPEVFKDLMFTSKSDVWAYGVLLYEIFS 2135
Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLR-LTELLERGERLPRPDKCPC-EVYHLMKNCWET 1154
+ G M R +T++ + LP P CP ++ +MK C +
Sbjct 2136 FGEE--------------PYGSMDSRRVITDVRDGNLTLPVPPYCPSKKICKVMKMCLIS 2181
Query 1155 EASFRPTFENLIPILKTVHEKYQGQ 1179
+ + R +F ++ I +T + Q Q
Sbjct 2182 DPNKRASFATILKIFETCRDDQQSQ 2206
Score = 70.9 bits (172), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 68/248 (27%), Positives = 119/248 (48%), Gaps = 27/248 (11%)
Query 635 QELRVVLKVLDP--SHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
++++V +K L P ++HD + F + A L++ + H ++ GVCV + +++ EY+E
Sbjct 1956 KQVKVAVKQLRPKSANHDFDRMMFMKEAILLNNLDH-NIVKELGVCVSPGQGLILLEYME 2014
Query 692 HGPLDVWLRRERGHVPMAWK------MVVAQQLASALSYLENKNLVHGNVCGRNILLA-R 744
G L +LR A + + ++ +A ++YLE VH N+ R LL+ R
Sbjct 2015 GGNLLNFLRESAPSEMQASELSTRDLLAISVDIARGMNYLERLPHVHKNLSARKCLLSGR 2074
Query 745 LGLAEGTSPFIKLSDP-GVGLGALSRE--ERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
G+A+ +++ P + G ++R E ++ + W+APE ++ D W +G
Sbjct 2075 PGVAK-----LEMGMPRALSKGEINRVDLESMQSVKWMAPEVFKDLM--FTSKSDVWAYG 2127
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP---EPSCP--QLATLTSQCLTYEPTQR 856
L EI GE P S S + R L P CP ++ + CL +P +R
Sbjct 2128 VLLYEIFSFGEEPYGSMD-SRRVITDVRDGNLTLPVPPYCPSKKICKVMKMCLISDPNKR 2186
Query 857 PSFRTILR 864
SF TIL+
Sbjct 2187 ASFATILK 2194
>sp|Q9VXE5|PAKM_DROME Serine/threonine-protein kinase PAK mbt
OS=Drosophila melanogaster OX=7227 GN=mbt PE=1 SV=2
Length=639
Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 64/211 (30%), Positives = 101/211 (48%), Gaps = 16/211 (8%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
A DP + L +GEG G V + T+ TG VAVK K D Q R
Sbjct 361 AGDP----RENLDHFNKIGEGSTGTVCIA----TDKSTGRQVAVK--KMDLRKQQRRELL 410
Query 946 -QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA 1004
E+ I+R +H +I++ E L +VMEY+ G+L D + + Q+
Sbjct 411 FNEVVIMRDYHHPNIVETYSSFLVNDE--LWVVMEYLEGGALTDIVTHSRMDEEQIATVC 468
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+Q + +AYLH+Q IHRD+ + ++LL D VK+ DFG V E + + +P
Sbjct 469 KQCLKALAYLHSQGVIHRDIKSDSILLAADGRVKLSDFGFCAQV--SQELPKRKSLVGTP 526
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+W +PE + + D+WS G+ + E++
Sbjct 527 -YWMSPEVISRLPYGPEVDIWSLGIMVIEMV 556
Score = 46.6 bits (109), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 59/246 (24%), Positives = 102/246 (41%), Gaps = 32/246 (13%)
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
D+ +V +K +D + +M H ++ + + E +V EY+E
Sbjct 387 DKSTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYHHPNIVETYSSFLVNDELWVVMEYLE 446
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G L + R + V +Q AL+YL ++ ++H ++ +ILLA A+G
Sbjct 447 GGALTDIVTHSR--MDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLA----ADGR 500
Query 752 SPFIKLSDPG----VGLGALSREERVERIPWLAPEC---LPGGANSLSTAMDKWGFGATL 804
+KLSD G V R+ V W++PE LP G +D W G +
Sbjct 501 ---VKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVISRLPYGPE-----VDIWSLGIMV 552
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------CPQLATLTSQCLTYEPTQRP 857
+E+ DGE P + P + +R + P+ P+L + + L +P QR
Sbjct 553 IEMV-DGEPPFFNEPPLQA---MRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRA 608
Query 858 SFRTIL 863
+ +L
Sbjct 609 TAAELL 614
>sp|Q1ZXD6|ROCO5_DICDI Probable serine/threonine-protein kinase
roco5 OS=Dictyostelium discoideum OX=44689 GN=roco5 PE=3 SV=1
Length=2800
Score = 92.4 bits (228), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 78/282 (28%), Positives = 128/282 (45%), Gaps = 39/282 (14%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-----WKQEIDIL 951
L+ I +GEG FG V G++VA+K + D G + +++E+ +
Sbjct 2175 LEIIEKVGEGGFGIVY------KGKLRGQLVAIKQITIDSGQAEAASEIYREFRREVWLS 2228
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICE 1009
TL H I+ KG C D +VMEY+P G+L +L + SI L A I +
Sbjct 2229 NTLTHPSIVSLKGYCLD----PCCIVMEYIPNGTLYSHLRKSFSSITWQLKLKIAINIAD 2284
Query 1010 GMAYLH--AQHYIHRDLAARNVLLDNDR----LVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+ ++H HRDL + N+L+ +D + K+ DFG +AV + D S
Sbjct 2285 AIKHMHGFTPKICHRDLKSPNILMLSDMNAAVVCKVSDFGETRAVVTS----ALGRDKLS 2340
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
W +PE ++ ++ +DV+SFG+ L+E+LT P +A + +
Sbjct 2341 NPIWLSPEIMRGDEYTEKADVYSFGIVLWEILTGLLPFDEYP--------VAHSSF-MYQ 2391
Query 1124 LTELLERGERLPRPDKCPC---EVYHLMKNCWETEASFRPTF 1162
L + + G R P C + L+ +CW+ + RPTF
Sbjct 2392 LEDEITNGLRPTIPQNSVCGHPDFITLITDCWQNDPLKRPTF 2433
Score = 58.9 bits (141), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 67/274 (24%), Positives = 114/274 (42%), Gaps = 32/274 (12%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETAS----LMSQVSHTHLAFVHGVCVRGPENIM 685
G+ RGQ + + +D + A Y L + ++H + + G C+ +
Sbjct 2192 GKLRGQLVAIKQITIDSGQAEAASEIYREFRREVWLSNTLTHPSIVSLKGYCLD--PCCI 2249
Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLA 743
V EY+ +G L LR+ + K+ +A +A A+ ++ + H ++ NIL+
Sbjct 2250 VMEYIPNGTLYSHLRKSFSSITWQLKLKIAINIADAIKHMHGFTPKICHRDLKSPNILM- 2308
Query 744 RLGLAEGTSPFI-KLSDPG----VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKW 798
L++ + + K+SD G V AL R++ I WL+PE + G + + D +
Sbjct 2309 ---LSDMNAAVVCKVSDFGETRAVVTSALGRDKLSNPI-WLSPEIMRG--DEYTEKADVY 2362
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE---PSCPQ--------LATLTSQ 847
FG L EI G P + YQ + + P+ PQ TL +
Sbjct 2363 SFGIVLWEI-LTGLLPFDEYPVAHSSFMYQLEDEITNGLRPTIPQNSVCGHPDFITLITD 2421
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
C +P +RP+F I L + N A T N
Sbjct 2422 CWQNDPLKRPTFIDIHSRLLIMSGLNPATATTTN 2455
>sp|Q9N2L7|PLK2_CAEEL Serine/threonine-protein kinase plk-2 OS=Caenorhabditis
elegans OX=6239 GN=plk-2 PE=1 SV=1
Length=632
Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 71/217 (33%), Positives = 106/217 (49%), Gaps = 13/217 (6%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQH 940
PD P K +K + LG+G F +CY+ N TGE+ A K + KA Q+
Sbjct 21 PDVPDVILDGERKTRYEKGKFLGKGGFA----HCYELRNKSTGELFAGKVVPKALLIKQY 76
Query 941 -RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLA 998
R QE+ I R L H +++K ED+ ++ + +E P SL + + R ++
Sbjct 77 QRDKMAQEVQIHRNLQHRNVVKLYHFFEDKS--NVYITLELCPRRSLMELHKRRKAVTEP 134
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
+ F QI EG+ YLH +HRDL N+ L+++ VKIGDFGLA R +
Sbjct 135 EARYFTYQIVEGVLYLHNLKIVHRDLKLGNLFLNDELQVKIGDFGLATTCDNDE---RKK 191
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+P + APE L + + D+W+ G LY LL
Sbjct 192 TLCGTPN-YIAPEVLNKIGHSFEVDLWAIGCILYILL 227
>sp|Q41328|PTI1_SOLLC Pto-interacting protein 1 OS=Solanum lycopersicum
OX=4081 GN=PTI1 PE=1 SV=2
Length=354
Score = 88.6 bits (218), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 82/296 (28%), Positives = 131/296 (44%), Gaps = 33/296 (11%)
Query 897 LKKIRD-------LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
LK I D +GEG +G+V +G A+K L D Q + ++
Sbjct 61 LKDITDNFGSKALIGEGSYGRVYHGVLK-----SGRAAAIKKL--DSSKQPDREFLAQVS 113
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQ 999
++ L E++++ G C D G + L EY P GSL D L P + AQ
Sbjct 114 MVSRLKDENVVELLGYCVDGGFRVL--AYEYAPNGSLHDILHGRKGVKGAQPGPVLSWAQ 171
Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYY 1055
+ A +G+ YLH + H IHRD+ + N+LL +D + KI DF L+ P+ +
Sbjct 172 RVKIAVGAAKGLEYLHEKAQPHIIHRDIKSSNILLFDDDVAKIADFDLSNQAPDMAARLH 231
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGI 1114
R G ++APE + SDV+SFGV L ELLT + P L+
Sbjct 232 STRVLG--TFGYHAPEYAMTGQLSSKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTW 289
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
A +++ ++ + ++ P K ++ + C + EA FRP ++ L+
Sbjct 290 ATPRLSEDKVKQCVDARLNTDYPPKAIAKMAAVAALCVQYEADFRPNMSIVVKALQ 345
Score = 46.2 bits (108), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 62/247 (25%), Positives = 102/247 (41%), Gaps = 35/247 (14%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRE--RGHVP---M 708
F S++S++ ++ + G CV G ++ EY +G L D+ R+ +G P +
Sbjct 108 FLAQVSMVSRLKDENVVELLGYCVDGGFRVLAYEYAPNGSLHDILHGRKGVKGAQPGPVL 167
Query 709 AW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+W ++ +A A L YL K +++H ++ NILL +A+ LS+
Sbjct 168 SWAQRVKIAVGAAKGLEYLHEKAQPHIIHRDIKSSNILLFDDDVAKIAD--FDLSNQAPD 225
Query 764 LGALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ A RV + APE G LS+ D + FG LLE+ G P+ P
Sbjct 226 MAARLHSTRVLGTFGYHAPEYAMTG--QLSSKSDVYSFGVVLLEL-LTGRKPVDHTLPRG 282
Query 823 KEHFYQ-RQHRLPEPSCPQL--ATLTSQ---------------CLTYEPTQRPSFRTILR 864
++ RL E Q A L + C+ YE RP+ +++
Sbjct 283 QQSLVTWATPRLSEDKVKQCVDARLNTDYPPKAIAKMAAVAALCVQYEADFRPNMSIVVK 342
Query 865 DLTRLQP 871
L L P
Sbjct 343 ALQPLLP 349
>sp|Q86IX1|DST1_DICDI Serine/threonine-protein kinase dst1 OS=Dictyostelium
discoideum OX=44689 GN=dst1 PE=3 SV=1
Length=737
Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 64/214 (30%), Positives = 108/214 (50%), Gaps = 19/214 (9%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
PD P T++H + LG+G FG+V + + G++VA+K + D +
Sbjct 22 PDDPQ---TIYHIQ-----ERLGKGSFGQV----FKAVHFANGKVVAIKIISLD-DQEAI 68
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQL 1000
++EI IL + +I++Y G + L +VMEY GS+ D L +I ++
Sbjct 69 KDVRKEISILAECNYPNIVQYFGSY--FKDHQLWIVMEYCGGGSVSDLLQVIDTISEDEI 126
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
L ++ +G+ YLH IHRD+ N+LL++ VK+ DFG++ + + R
Sbjct 127 ALICREALKGLNYLHEFKKIHRDIKGGNILLNDRGEVKLADFGVSAQL---FNTFSKRNT 183
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
+W APE ++E K+ +DVWS G+T E+
Sbjct 184 FVGTPYWMAPEVIQENKYDGKADVWSLGITAIEM 217
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 40/166 (24%), Positives = 65/166 (39%), Gaps = 30/166 (18%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSR 769
++ ++ L+YL +H ++ G NILL G +KL+D GV S+
Sbjct 128 LICREALKGLNYLHEFKKIHRDIKGGNILLNDRGE-------VKLADFGVSAQLFNTFSK 180
Query 770 EERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
P W+APE + N D W G T +E+ + P+ H +
Sbjct 181 RNTFVGTPYWMAPEVI--QENKYDGKADVWSLGITAIEMA-------EGLPPNSNVHPMR 231
Query 829 RQHRLPEPSCPQLAT----------LTSQCLTYEPTQRPSFRTILR 864
+P P L S+CLT +P +RP+ + +L
Sbjct 232 VIFMIPREESPALTDKSIWSDKFQDFISKCLTKDPAERPTAKELLN 277
>sp|Q9LS95|PERK6_ARATH Putative proline-rich receptor-like protein
kinase PERK6 OS=Arabidopsis thaliana OX=3702 GN=PERK6 PE=2
SV=2
Length=700
Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 75/227 (33%), Positives = 106/227 (47%), Gaps = 18/227 (8%)
Query 877 VLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC 936
L N + D + + R LG+G FG V G+ +AVK+LKA
Sbjct 317 ALGFNKSTFTYDELAAATQGFSQSRLLGQGGFGYVHKGILP-----NGKEIAVKSLKAGS 371
Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-- 994
G R ++ E+DI+ ++H ++ G C G++ LV E++P +L +L S
Sbjct 372 GQGERE-FQAEVDIISRVHHRFLVSLVGYCIAGGQR--MLVYEFLPNDTLEFHLHGKSGK 428
Query 995 -IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
+ L A +G+AYLH IHRD+ A N+LLD K+ DFGLAK +
Sbjct 429 VLDWPTRLKIALGSAKGLAYLHEDCHPRIIHRDIKASNILLDESFEAKVADFGLAKLSQD 488
Query 1051 GHEYYRVREDGDSPVFWY-APECLKEYKFYYASDVWSFGVTLYELLT 1096
+ R G F Y APE K SDV+SFGV L EL+T
Sbjct 489 NVTHVSTRIMG---TFGYLAPEYASSGKLTDRSDVFSFGVMLLELVT 532
Score = 45.8 bits (107), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 46/166 (28%), Positives = 76/166 (46%), Gaps = 24/166 (14%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F ++S+V H L + G C+ G + ++V E++ + L+ L + G V + W ++
Sbjct 378 FQAEVDIISRVHHRFLVSLVGYCIAGGQRMLVYEFLPNDTLEFHLHGKSGKV-LDWPTRL 436
Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+A A L+YL ++H ++ NILL S K++D GL LS+
Sbjct 437 KIALGSAKGLAYLHEDCHPRIIHRDIKASNILLDE-------SFEAKVAD--FGLAKLSQ 487
Query 770 EERVE---RI----PWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ RI +LAPE G L+ D + FG LLE+
Sbjct 488 DNVTHVSTRIMGTFGYLAPEYASSG--KLTDRSDVFSFGVMLLELV 531
>sp|Q9SGY7|PEK11_ARATH Putative proline-rich receptor-like protein
kinase PERK11 OS=Arabidopsis thaliana OX=3702 GN=PERK11
PE=2 SV=2
Length=718
Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 88/289 (30%), Positives = 137/289 (47%), Gaps = 39/289 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG C G+ VA+K LK+ +R +K E++I+ ++H H++
Sbjct 376 VGEGGFG-----CVYKGILFEGKPVAIKQLKSVSAEGYRE-FKAEVEIISRVHHRHLVSL 429
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLHAQ-- 1017
G C E+ L+ E+VP +L +L ++ + ++ + A +G+AYLH
Sbjct 430 VGYC--ISEQHRFLIYEFVPNNTLDYHLHGKNLPVLEWSRRVRIAIGAAKGLAYLHEDCH 487
Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075
IHRD+ + N+LLD++ ++ DFGLA+ + R G F Y APE
Sbjct 488 PKIIHRDIKSSNILLDDEFEAQVADFGLARLNDTAQSHISTRVMG---TFGYLAPEYASS 544
Query 1076 YKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
K SDV+SFGV L EL+T D+SQ P L+ A+ RL E +E+G+
Sbjct 545 GKLTDRSDVFSFGVVLLELITGRKPVDTSQ--PLGEESLVEWAR-----PRLIEAIEKGD 597
Query 1133 -------RLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILKT 1171
RL D EVY +++ +C A RP ++ L T
Sbjct 598 ISEVVDPRLEN-DYVESEVYKMIETAASCVRHSALKRPRMVQVVRALDT 645
Score = 42.7 bits (99), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 21/184 (11%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F ++S+V H HL + G C+ ++ E+V + LD L + V + W ++
Sbjct 411 FKAEVEIISRVHHRHLVSLVGYCISEQHRFLIYEFVPNNTLDYHLHGKNLPV-LEWSRRV 469
Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALS 768
+A A L+YL ++H ++ NILL A+ ++D G+ L +
Sbjct 470 RIAIGAAKGLAYLHEDCHPKIIHRDIKSSNILLDDEFEAQ-------VADFGLARLNDTA 522
Query 769 REERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ R+ +LAPE G L+ D + FG LLE+ G P+ + P +E
Sbjct 523 QSHISTRVMGTFGYLAPEYASSGK--LTDRSDVFSFGVVLLEL-ITGRKPVDTSQPLGEE 579
Query 825 HFYQ 828
+
Sbjct 580 SLVE 583
>sp|Q55D99|PAKA_DICDI Serine/threonine-protein kinase pakA OS=Dictyostelium
discoideum OX=44689 GN=pakA PE=1 SV=1
Length=1197
Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 62/235 (26%), Positives = 117/235 (50%), Gaps = 30/235 (13%)
Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE 925
LT P L D+++++ DP K+ I +GEG G+V ++ N T +
Sbjct 890 LTDEPPVTLNDLISLD------DP----KKIYYNINKIGEGGAGEV----FEAINSRTNQ 935
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
+A+K +K Q+ EI +++ HE+I++Y E L + ME++ G
Sbjct 936 TIAIKKMKLKA--QNLKTVINEIGMMKNSNHENIVQYIDSYIVADE--LWVAMEFMSGGC 991
Query 986 LRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
L + L ++ + +Q+ Q++ G+ Y+H + IHRD+ + N+L+ + +K+ DF
Sbjct 992 LTEVLDQYRDIQLNESQIAFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADF 1051
Query 1043 GLAKAVPEGHEYYRVREDGDSPV---FWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
G A + + +R++ +S V +W APE ++ + + DVWS G+ E+
Sbjct 1052 GYAAQLTQ------IRQERNSVVGTPYWMAPELIRGNNYDFKVDVWSLGIMTREM 1100
Score = 39.7 bits (91), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 31/105 (30%), Positives = 48/105 (46%), Gaps = 14/105 (13%)
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS-REER 772
V Q++ L Y+ N +H ++ NIL+ G + IKL+D G R+ER
Sbjct 1012 VCQEVLRGLEYIHKFNRIHRDIKSDNILI-------GANGEIKLADFGYAAQLTQIRQER 1064
Query 773 VERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
+ W+APE + G N+ +D W G E+ +GE P
Sbjct 1065 NSVVGTPYWMAPELIRG--NNYDFKVDVWSLGIMTREMA-EGEPP 1106
>sp|P06782|SNF1_YEAST Carbon catabolite-derepressing protein kinase
OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=SNF1 PE=1 SV=1
Length=633
Score = 90.9 bits (224), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 78/220 (35%), Positives = 108/220 (49%), Gaps = 19/220 (9%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGP 938
NP S +D H + ++ LGEG FGKV L Y T TG+ VA+K + K
Sbjct 41 NPKSSLADGA--HIGNYQIVKTLGEGSFGKVKL-AYHTT---TGQKVALKIINKKVLAKS 94
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGL 997
+ ++EI LR L H HIIK + + E + +V+EY L DY+ R +
Sbjct 95 DMQGRIEREISYLRLLRHPHIIKLYDVIKSKDE--IIMVIEYAG-NELFDYIVQRDKMSE 151
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ F QQI + Y H +HRDL N+LLD VKI DFGL+ + +G+ +
Sbjct 152 QEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGN---FL 208
Query 1058 REDGDSPVFWYAPECLKEYKFYYA--SDVWSFGVTLYELL 1095
+ SP + APE + K Y DVWS GV LY +L
Sbjct 209 KTSCGSPNY-AAPEVISG-KLYAGPEVDVWSCGVILYVML 246
Score = 41.6 bits (96), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 55/241 (23%), Positives = 98/241 (41%), Gaps = 30/241 (12%)
Query 638 RVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+V LK+++ + D+ S + + H H+ ++ V E IMV EY +
Sbjct 80 KVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNEL 139
Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
D ++R++ A + QQ+ SA+ Y +VH ++ N+LL
Sbjct 140 FDYIVQRDKMSEQEARRFF--QQIISAVEYCHRHKIVHRDLKPENLLLDE-------HLN 190
Query 755 IKLSDPGVGLGALSREERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATL-LEIC 808
+K++D GL + + + + APE + G + +D W G L + +C
Sbjct 191 VKIAD--FGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYVMLC 247
Query 809 ----FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
FD E+ P ++ + LP+ P A L + L P R S I++
Sbjct 248 RRLPFDDESI-----PVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQ 302
Query 865 D 865
D
Sbjct 303 D 303
>sp|O94168|SNF1_CANTR Carbon catabolite-derepressing protein kinase
OS=Candida tropicalis OX=5482 GN=SNF1 PE=3 SV=1
Length=619
Score = 90.9 bits (224), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 77/219 (35%), Positives = 109/219 (50%), Gaps = 18/219 (8%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQ 939
P P +P RY + I+ LGEG FGKV L + GTG+ VA+K + K
Sbjct 38 PIDPNVNPANRIGRY-QIIKTLGEGSFGKVKL----AQHVGTGQKVALKIINRKTLAKSD 92
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLA 998
+ ++EI LR L H HIIK + + E + +V+E+ L DY+ R +
Sbjct 93 MQGRVEREISYLRLLRHPHIIKLYDVIKSKDE--IIMVIEFAG-KELFDYIVQRGKMPED 149
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
+ F QQI + Y H +HRDL N+LLD+ VKI DFGL+ + +G+ ++
Sbjct 150 EARRFFQQIIAAVEYCHRHKIVHRDLKPENLLLDDQLNVKIADFGLSNIMTDGN---FLK 206
Query 1059 EDGDSPVFWYAPECLKEYKFYYA--SDVWSFGVTLYELL 1095
SP + APE + K Y DVWS GV LY +L
Sbjct 207 TSCGSPNY-AAPEVISG-KLYAGPEVDVWSSGVILYVML 243
Score = 37.4 bits (85), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 51/241 (21%), Positives = 92/241 (38%), Gaps = 22/241 (9%)
Query 634 GQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
G +V LK+++ + D+ S + + H H+ ++ V E IMV E+
Sbjct 73 GTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEFA 132
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
D + +RG +P QQ+ +A+ Y +VH ++ N+LL
Sbjct 133 GKELFDYIV--QRGKMPEDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLLL-------D 183
Query 751 TSPFIKLSDPGVGLGALSREERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATLL 805
+K++D GL + + + + APE + G + +D W G +L
Sbjct 184 DQLNVKIAD--FGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSSGV-IL 239
Query 806 EICFDGEAPLQSR-SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ G P P+ + + LP P L ++ L P R + I+
Sbjct 240 YVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSPGAKHLLTRMLVVNPLNRITIHEIME 299
Query 865 D 865
D
Sbjct 300 D 300
>sp|B5DE93|CDK12_XENTR Cyclin-dependent kinase 12 OS=Xenopus tropicalis
OX=8364 GN=cdk12 PE=2 SV=1
Length=1239
Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 67/215 (31%), Positives = 103/215 (48%), Gaps = 37/215 (17%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958
+GEG +G+V Y + TGE+VA+K ++ D + G+ +EI ILR L H+
Sbjct 716 IGEGTYGQV----YKAKDKDTGELVALKKVRLD---NEKEGFPITAIREIKILRQLIHKS 768
Query 959 IIKYKGCCEDQGEK--------SLQLVMEYVPLGSLRDYLPRHSIGLAQ-----LLLFAQ 1005
++ K D+ + + LV EY+ D + GL Q + F +
Sbjct 769 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMD----HDLMGLLESGLVQFSEDHIKSFMK 824
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK--AVPEGHEYYRVREDGDS 1063
Q+ EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ + E Y
Sbjct 825 QLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYSSEESRPYT-----NKV 879
Query 1064 PVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096
WY P L E ++ A DVWS G L EL T
Sbjct 880 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFT 914
Score = 37.0 bits (84), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 16/129 (12%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILL 742
+V EY++H D+ E G V + + + +QL L Y KN +H ++ NILL
Sbjct 794 LVFEYMDH---DLMGLLESGLVQFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILL 850
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKW 798
G IKL+D G+ S E R ++ W P L G + A+D W
Sbjct 851 NNSGQ-------IKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVW 903
Query 799 GFGATLLEI 807
G L E+
Sbjct 904 SCGCILGEL 912
>sp|Q9LSL5|LRK92_ARATH L-type lectin-domain containing receptor
kinase IX.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK92 PE=1
SV=1
Length=675
Score = 91.3 bits (225), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 71/211 (34%), Positives = 105/211 (50%), Gaps = 33/211 (16%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LGEG FG V Y+ MVAVK L D Q ++ + E+ I+ L H +++
Sbjct 354 RKLGEGGFGAV----YEGNLKEINTMVAVKKLSGDS-RQGKNEFLNEVKIISKLRHRNLV 408
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------PRHSIGLAQLLLFAQQICE 1009
+ G C ++ E L+ E VP GSL +L R+ IGL +
Sbjct 409 QLIGWCNEKNE--FLLIYELVPNGSLNSHLFGKRPNLLSWDIRYKIGLG--------LAS 458
Query 1010 GMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+ YLH Q +HRD+ A N++LD++ VK+GDFGLA+ + HE G + F
Sbjct 459 ALLYLHEEWDQCVLHRDIKASNIMLDSEFNVKLGDFGLARLM--NHE-LGSHTTGLAGTF 515
Query 1067 WY-APECLKEYKFYYASDVWSFGVTLYELLT 1096
Y APE + + SD++SFG+ L E++T
Sbjct 516 GYMAPEYVMKGSASKESDIYSFGIVLLEIVT 546
>sp|Q9GN62|PAR4_CAEEL Serine/threonine-protein kinase par-4 OS=Caenorhabditis
elegans OX=6239 GN=par-4 PE=1 SV=2
Length=617
Score = 90.9 bits (224), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 76/240 (32%), Positives = 122/240 (51%), Gaps = 21/240 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW---KQEIDILRTLYHEHI 959
+G G +GKV C D T AVK +K D + +GW + E+ ILR + H ++
Sbjct 189 IGTGSYGKVK-ECIDMY---TLTRRAVKIMKYDKLRKITNGWENIRSEMSILRRMNHRNV 244
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMAYL 1014
IK + + +V EY +GS++ L R +IG + + ++C+G+ YL
Sbjct 245 IKLIEIFNIPAKGKVYMVFEYC-IGSVQQLLDMEPARRLTIGESHAIFI--ELCQGLNYL 301
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL- 1073
H++ H+D+ N+L+ D VKI DFG+A+ + R + +P F PEC+
Sbjct 302 HSKRVSHKDIKPGNLLVSIDFTVKICDFGVAEQINLFQRDGRCTKVNGTPKFQ-PPECIY 360
Query 1074 KEYKFY--YASDVWSFGVTLYELLTHCDSSQSPP-TKFLELIGIAQGQM-TVLRLTELLE 1129
+ F+ Y +D+WS GVTLY L++ + P K E IG QM T ++LT+ L+
Sbjct 361 GNHDFFDGYKADMWSAGVTLYNLVSGKYPFEKPVLLKLYECIGTEPLQMPTNVQLTKDLQ 420
>sp|E1BK52|STK10_BOVIN Serine/threonine-protein kinase 10 OS=Bos
taurus OX=9913 GN=STK10 PE=3 SV=3
Length=966
Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 60/200 (30%), Positives = 105/200 (53%), Gaps = 17/200 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+LG+G FGKV Y N TG + A K ++ + + + EI+IL T H +I+K
Sbjct 41 ELGDGAFGKV----YKAKNKETGALAAAKVIETN-SEEELEDYIVEIEILATCDHPYIVK 95
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019
G G+ L +++E+ P G++ + GL Q+ + +Q+ E + +LH +
Sbjct 96 LLGAYYYDGK--LWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALTFLHGKKI 153
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP-----ECLK 1074
IHRDL A NVL+ + +++ DFG++ + + + R+ +W AP E +K
Sbjct 154 IHRDLKAGNVLMTLEGDIRLADFGVS---AKNLKTLQKRDSFIGTPYWMAPEVVMCETMK 210
Query 1075 EYKFYYASDVWSFGVTLYEL 1094
+ + Y +D+WS G+TL E+
Sbjct 211 DTPYDYKADIWSLGITLIEM 230
Score = 41.6 bits (96), Expect = 0.056, Method: Compositional matrix adjust.
Identities = 30/103 (29%), Positives = 47/103 (46%), Gaps = 14/103 (14%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV---GLGALSR 769
VV +Q+ AL++L K ++H ++ N+L+ G I+L+D GV L L +
Sbjct 136 VVCRQMLEALTFLHGKKIIHRDLKAGNVLMTLEG-------DIRLADFGVSAKNLKTLQK 188
Query 770 EERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808
+ P W+APE C D W G TL+E+
Sbjct 189 RDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMA 231
>sp|Q28DZ1|IKKA_XENTR Inhibitor of nuclear factor kappa-B kinase
subunit alpha OS=Xenopus tropicalis OX=8364 GN=chuk PE=2
SV=1
Length=743
Score = 91.3 bits (225), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 24/206 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V LY N TGE+ A+K+ + + +++ W QEI I++ L H +++K
Sbjct 21 LGTGGFGNVCLY----QNRETGELKAIKSCRLELSMKNKERWCQEIQIMKRLNHPNVVK- 75
Query 963 KGCCEDQGEKSL------QLVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMA 1012
CE E L MEY G LR L P + GL +Q+L I G+
Sbjct 76 --ACEVPPEMDFLVNDVPHLAMEYCAGGDLRKLLNKPENCCGLKESQVLNLMSDIGSGIQ 133
Query 1013 YLHAQHYIHRDLAARNVLLD--NDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH + IHRDL N++L N + V KI D G AK + +G + + + A
Sbjct 134 YLHEKRIIHRDLKPENIVLQECNGKTVHKIIDLGYAKDLDQG----SLCTSFVGTLQYLA 189
Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095
PE + + D WSFG ++E +
Sbjct 190 PELFENKPYSVTVDYWSFGTMVFECI 215
>sp|Q9CAH1|Y1725_ARATH Putative receptor-like protein kinase At1g72540
OS=Arabidopsis thaliana OX=3702 GN=At1g72540 PE=2 SV=1
Length=450
Score = 89.7 bits (221), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 76/211 (36%), Positives = 103/211 (49%), Gaps = 19/211 (9%)
Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTL 954
K LGEG FG+V + D G + VAVKALK + G HR W E+ IL L
Sbjct 84 FSKYNFLGEGGFGEVYKGFVDDSLKTGLKDQPVAVKALKREGGQGHRE-WLAEVIILGQL 142
Query 955 YHEHIIKYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL------AQLLLFAQQI 1007
H H++ G CCED LV EY+ G+L D+L + G ++LL A
Sbjct 143 KHPHLVNLVGYCCEDDER---LLVYEYMERGNLEDHLFQKYGGALPWLTRVKILLGA--- 196
Query 1008 CEGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
+G+ +LH Q I+RD N+LL +D K+ DFGLA E + + +
Sbjct 197 AKGLEFLHKQEKPVIYRDFKPSNILLSSDFSSKLSDFGLATDGSEEEDSNFTKSVMGTEG 256
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+ APE + SDV+SFGV L E+LT
Sbjct 257 YA-APEYISAGNLTTMSDVFSFGVVLLEMLT 286
Score = 60.1 bits (144), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 63/241 (26%), Positives = 104/241 (43%), Gaps = 52/241 (22%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719
++ Q+ H HL + G C E ++V EY+E G L D ++ G +P ++ + A
Sbjct 138 ILGQLKHPHLVNLVGYCCEDDERLLVYEYMERGNLEDHLFQKYGGALPWLTRVKILLGAA 197
Query 720 SALSYL--ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER----- 772
L +L + K +++ + NILL+ ++ +S KLSD G+ E+
Sbjct 198 KGLEFLHKQEKPVIYRDFKPSNILLS----SDFSS---KLSDFGLATDGSEEEDSNFTKS 250
Query 773 -VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
+ + APE + G +L+T D + FG LLE+ L +R EK + QR
Sbjct 251 VMGTEGYAAPEYISAG--NLTTMSDVFSFGVVLLEM-------LTARKAVEK-YRAQRGR 300
Query 832 RLPEPSCPQL--------------------------ATLTSQCLTYEPTQRPSFRTILRD 865
L E + P L A L QCL++ P RP+ T+++
Sbjct 301 NLVEWARPMLKDPNKLERIIDPSLEGKYSVEGIRKAAALAYQCLSHNPKSRPTMTTVVKT 360
Query 866 L 866
L
Sbjct 361 L 361
>sp|Q02111|KPCT_MOUSE Protein kinase C theta type OS=Mus musculus
OX=10090 GN=Prkcq PE=1 SV=1
Length=707
Score = 90.9 bits (224), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 68/209 (33%), Positives = 103/209 (49%), Gaps = 23/209 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI-LRTLYHEHIIK 961
LG+G FGKV L + TN + A+KALK D ++ + +L EH
Sbjct 386 LGKGSFGKVFLAEFKRTN----QFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFL 441
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
C Q +++L VMEY+ G L ++ H L++ +A ++ G+ +LH++ +
Sbjct 442 THMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEVILGLQFLHSKGIV 501
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WYAPECLKE 1075
+RDL N+LLD D +KI DFG+ K G D + F + APE L
Sbjct 502 YRDLKLDNILLDRDGHIKIADFGMCKENMLG--------DAKTNTFCGTPDYIAPEILLG 553
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
K+ ++ D WSFGV +YE+L QSP
Sbjct 554 QKYNHSVDWWSFGVLVYEMLI----GQSP 578
>sp|B3NS99|PTK7_DROER Tyrosine-protein kinase-like otk OS=Drosophila
erecta OX=7220 GN=otk PE=3 SV=1
Length=1033
Score = 91.3 bits (225), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 62/256 (24%), Positives = 122/256 (48%), Gaps = 31/256 (12%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY G
Sbjct 781 QLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPH--YMVLEYTDWG 838
Query 985 SLRDYLPRHS---------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029
L+ +L + + +Q+L A QI GM ++ + HRDLA RN
Sbjct 839 DLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRNC 898
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
++ ++ +VK+ L K EY++ R + P+ W APEC++E ++ SD++++GV
Sbjct 899 VISSEFIVKVSYPALCKD-KYSREYHKHR-NTLLPIRWLAPECIQEDEYTTKSDIFAYGV 956
Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149
++EL +++ P + + + Q L + + P + ++
Sbjct 957 VVWELFNQ--ATKLPHEELTNEQVVQRSQAGSLEWS----------VAEATPDSLREILL 1004
Query 1150 NCWETEASFRPTFENL 1165
+CW + RP+F L
Sbjct 1005 SCWVSNPKERPSFSQL 1020
Score = 55.5 bits (132), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 65/262 (25%), Positives = 104/262 (40%), Gaps = 44/262 (17%)
Query 636 ELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
E V++K L+ + A F L+ +SH + + G+C + MV EY + G
Sbjct 780 EQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDWGD 839
Query 695 LDVWLRRERGHVPMAWK-------------MVVAQQLASALSYLENKNLVHGNVCGRNIL 741
L +L G V A + VA Q+A + + H ++ RN +
Sbjct 840 LKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRNCV 899
Query 742 LARLGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAM 795
+ +S FI K+S P + SRE R I WLAPEC+ + +T
Sbjct 900 I--------SSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQ--EDEYTTKS 949
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQH------RLPEPSCPQLATLTS 846
D + +G + E+ F+ L P E+ E QR + E + L +
Sbjct 950 DIFAYGVVVWEL-FNQATKL----PHEELTNEQVVQRSQAGSLEWSVAEATPDSLREILL 1004
Query 847 QCLTYEPTQRPSFRTILRDLTR 868
C P +RPSF + L++
Sbjct 1005 SCWVSNPKERPSFSQLGAALSK 1026
>sp|Q9M2S4|LRKS4_ARATH L-type lectin-domain containing receptor
kinase S.4 OS=Arabidopsis thaliana OX=3702 GN=LECRKS4 PE=2
SV=1
Length=684
Score = 90.9 bits (224), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 75/221 (34%), Positives = 106/221 (48%), Gaps = 25/221 (11%)
Query 889 PTVFHKRYLKKIRD-------LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
P F R LKK + LG G FGKV Y G+ E VAVK + + R
Sbjct 331 PHRFSYRELKKATNGFGDKELLGSGGFGKV----YKGKLPGSDEFVAVKRISHESRQGVR 386
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGL 997
+ E+ + L H ++++ G C + + L LV +++P GSL YL P +
Sbjct 387 E-FMSEVSSIGHLRHRNLVQLLGWCRRRDD--LLLVYDFMPNGSLDMYLFDENPEVILTW 443
Query 998 AQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
Q + + G+ YLH Q IHRD+ A NVLLD++ ++GDFGLAK G +
Sbjct 444 KQRFKIIKGVASGLLYLHEGWEQTVIHRDIKAANVLLDSEMNGRVGDFGLAKLYEHGSDP 503
Query 1055 YRVREDGDSPVFWY-APECLKEYKFYYASDVWSFGVTLYEL 1094
R G F Y APE K K ++DV++FG L E+
Sbjct 504 GATRVVG---TFGYLAPELTKSGKLTTSTDVYAFGAVLLEV 541
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 65/255 (25%), Positives = 111/255 (44%), Gaps = 43/255 (17%)
Query 582 HRVDQKEITQLSH-------LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
HR +E+ + ++ LG G VY+G+L PG D
Sbjct 332 HRFSYRELKKATNGFGDKELLGSGGFGKVYKGKL--------------------PGSD-- 369
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
E V ++ S + F S + + H +L + G C R + ++V +++ +G
Sbjct 370 -EFVAVKRISHESRQGVR-EFMSEVSSIGHLRHRNLVQLLGWCRRRDDLLLVYDFMPNGS 427
Query 695 LDVWLRRERGHVPMAWK--MVVAQQLASALSYLE---NKNLVHGNVCGRNILL-ARLGLA 748
LD++L E V + WK + + +AS L YL + ++H ++ N+LL + +
Sbjct 428 LDMYLFDENPEVILTWKQRFKIIKGVASGLLYLHEGWEQTVIHRDIKAANVLLDSEMNGR 487
Query 749 EGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
G KL + G GA V +LAPE G L+T+ D + FGA LLE+
Sbjct 488 VGDFGLAKLYEHGSDPGA---TRVVGTFGYLAPELTKSG--KLTTSTDVYAFGAVLLEVA 542
Query 809 FDGEAPLQSRSPSEK 823
G P+++ + E+
Sbjct 543 C-GRRPIETSALPEE 556
>sp|Q9H4B4|PLK3_HUMAN Serine/threonine-protein kinase PLK3 OS=Homo
sapiens OX=9606 GN=PLK3 PE=1 SV=2
Length=646
Score = 90.5 bits (223), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 70/225 (31%), Positives = 109/225 (48%), Gaps = 14/225 (6%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933
LA + T +P +DP + YLK R LG+G F + CY+ T+ TG AVK +
Sbjct 41 LAGLPTSDPGRLITDPRS-GRTYLKG-RLLGKGGFAR----CYEATDTETGSAYAVKVIP 94
Query 934 AD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YL 990
P R EI++ R L H HI+++ ED ++ + +E SL +
Sbjct 95 QSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDA--DNIYIFLELCSRKSLAHIWK 152
Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
RH++ ++ + +QI G+ YLH + +HRDL N + + +K+GDFGLA +
Sbjct 153 ARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEP 212
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+ R + +P + APE L +DVWS G +Y LL
Sbjct 213 PEQ--RKKTICGTPNY-VAPEVLLRQGHGPEADVWSLGCVMYTLL 254
>sp|Q54TH6|Y9863_DICDI Probable serine/threonine-protein kinase
DDB_G0281745 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0281745
PE=3 SV=1
Length=597
Score = 90.5 bits (223), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 73/279 (26%), Positives = 127/279 (46%), Gaps = 36/279 (13%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
++G G +G VSL + G VA+K L + + ++E+ IL+ + H I++
Sbjct 339 EIGSGKYGSVSLGYW------LGTPVAIKKLHEN-NEETEILVQRELQILKEIRHPQIVQ 391
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019
+ G ++ ++ + ++ E++ G L D L I L + L + I + +LHA+
Sbjct 392 FLGVSRNEKDE-IHIITEFMDGGDLFDALIFGDIPLTWKEKLRISLDIAQSCRFLHARGI 450
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPE--GHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL ++N+LL +R K+ D GLA+ E Y V + W APE +
Sbjct 451 LHRDLKSQNILLSTNRRAKLCDLGLARMFEERINKRYTCVGTE-----IWMAPEVCLDQS 505
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ A DV+SFG+ L E++T + P + A L++ P
Sbjct 506 YSTAVDVFSFGIVLVEIITEKIPDERFPQHRFQFDAPA-----------FLKK-----VP 549
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
+CP + L +C + RP+F I +L T+ Y
Sbjct 550 KECPPDFSKLCVDCTKYNPKERPSF---IKVLDTIQNIY 585
Score = 69.3 bits (168), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 62/249 (25%), Positives = 116/249 (47%), Gaps = 40/249 (16%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDV 697
V +K L ++ + + ++ ++ H + GV + I ++TE+++ G D+
Sbjct 358 VAIKKLHENNEETEILVQRELQILKEIRHPQIVQFLGVSRNEKDEIHIITEFMDGG--DL 415
Query 698 WLRRERGHVPMAWK--MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+ G +P+ WK + ++ +A + +L + ++H ++ +NILL+ T+
Sbjct 416 FDALIFGDIPLTWKEKLRISLDIAQSCRFLHARGILHRDLKSQNILLS-------TNRRA 468
Query 756 KLSDPGVGLGALSREERVERI-------PWLAPE-CLPGGANSLSTAMDKWGFGATLLEI 807
KL D G+ A EER+ + W+APE CL S STA+D + FG L+EI
Sbjct 469 KLCDLGL---ARMFEERINKRYTCVGTEIWMAPEVCL---DQSYSTAVDVFSFGIVLVEI 522
Query 808 CFDGEAPLQSRSPSEK--EHFYQRQ-----HRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
+ + P E+ +H +Q ++P+ P + L C Y P +RPSF
Sbjct 523 -------ITEKIPDERFPQHRFQFDAPAFLKKVPKECPPDFSKLCVDCTKYNPKERPSFI 575
Query 861 TILRDLTRL 869
+L + +
Sbjct 576 KVLDTIQNI 584
>sp|Q00372|SNF1_CANGA Carbon catabolite-derepressing protein kinase
OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM
3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=SNF1
PE=3 SV=2
Length=612
Score = 90.5 bits (223), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 73/201 (36%), Positives = 102/201 (51%), Gaps = 17/201 (8%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHE 957
++ LGEG FGKV L Y T TG+ VA+K + K + ++EI LR L H
Sbjct 42 VKTLGEGSFGKVKL-AYHVT---TGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHP 97
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHA 1016
HIIK + + E + +V+EY L DY+ R+ + + F QQI + Y H
Sbjct 98 HIIKLYDVIKSKDE--IIMVIEYAG-NELFDYIVQRNKMSEQEARRFFQQIISAVEYCHR 154
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL N+LLD VKI DFGL+ + +G+ ++ SP + APE +
Sbjct 155 HKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGN---FLKTSCGSPNY-AAPEVISG- 209
Query 1077 KFYYA--SDVWSFGVTLYELL 1095
K Y DVWS GV LY +L
Sbjct 210 KLYAGPEVDVWSCGVILYVML 230
Score = 42.4 bits (98), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 64/289 (22%), Positives = 116/289 (40%), Gaps = 39/289 (13%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP--- 646
++S L G+R Y+ V+ G+ GK+ + G+ +V LK+++
Sbjct 25 NKVSSLADGSRVGNYQ---IVKTLGEGSFGKVKLAYHVTTGQ------KVALKIINKKVL 75
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
+ D+ S + + H H+ ++ V E IMV EY + D ++R +
Sbjct 76 AKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRNKMSE 135
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
A + QQ+ SA+ Y +VH ++ N+LL +K++D GL
Sbjct 136 QEARRFF--QQIISAVEYCHRHKIVHRDLKPENLLLDE-------HLNVKIAD--FGLSN 184
Query 767 LSREERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATL-LEIC----FDGEAPLQ 816
+ + + + APE + G + +D W G L + +C FD E+
Sbjct 185 IMTDGNFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYVMLCRRLPFDDESI-- 241
Query 817 SRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
P ++ + LP+ P + L + L P R S I++D
Sbjct 242 ---PVLFKNISNGVYTLPKFLSPGASDLIKRMLIVNPLNRISIHEIMQD 287
>sp|Q556S2|PAKH_DICDI Serine/threonine-protein kinase pakH OS=Dictyostelium
discoideum OX=44689 GN=pakH-1 PE=3 SV=1
Length=513
Score = 90.1 bits (222), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 60/200 (30%), Positives = 95/200 (48%), Gaps = 25/200 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA----DCGPQHRSGWKQEIDILRTLYHEH 958
LGEG FG V Y + + +A+K + D P + EI IL+ + +
Sbjct 48 LGEGSFGSV----YRAIHKSSNTSIAIKEFEIFEANDVEPISK-----EIQILKKCNNPY 98
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA----QLLLFAQQICEGMAYL 1014
++ Y G + + ++M+Y L S D + SIG ++ L QQ G+ YL
Sbjct 99 VVSYFGSIMLKNK--YWILMDYCSLSSFNDIM--QSIGKTFKEKEISLILQQSLLGLVYL 154
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H++ IHRD+ + N+LLD VKI DFG+++ + + +P +W APE L
Sbjct 155 HSKQIIHRDIKSANILLDETGQVKIADFGVSQQI---QSTFSKGSIAGTP-YWMAPEILN 210
Query 1075 EYKFYYASDVWSFGVTLYEL 1094
+ + DVWS G+ EL
Sbjct 211 QTDYNNKIDVWSLGIVAIEL 230
Score = 54.7 bits (130), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 39/151 (26%), Positives = 68/151 (45%), Gaps = 17/151 (11%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSRE 770
++ QQ L YL +K ++H ++ NILL G +K++D GV + + +
Sbjct 142 LILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQ-------VKIADFGVSQQIQSTFSK 194
Query 771 ERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
+ P W+APE L + +D W G +E+ DGE PL +P + R
Sbjct 195 GSIAGTPYWMAPEIL--NQTDYNNKIDVWSLGIVAIELA-DGEPPLSEVNPMRAMYMIGR 251
Query 830 Q----HRLPEPSCPQLATLTSQCLTYEPTQR 856
+ + P+ P+ + +CLT + +R
Sbjct 252 RPPPTFKDPKKWSPEFVSFVDKCLTKDINER 282
>sp|Q869N2|PAKB_DICDI Serine/threonine-protein kinase pakB OS=Dictyostelium
discoideum OX=44689 GN=pakB PE=1 SV=1
Length=852
Score = 90.9 bits (224), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 85/292 (29%), Positives = 138/292 (47%), Gaps = 38/292 (13%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DPT K + + +GEG G+V + TN+ VA+K K Q+ E
Sbjct 564 DPT---KLFGEGSTKIGEGAAGEVFVVTQLKTNN----KVAIK--KMPLNQQNMKLIVTE 614
Query 948 IDILRTLYHEHIIKYKGC--CEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGL--AQLLL 1002
I I+++ H++II Y D SL + ME++ G L + L + +S+ L AQ+
Sbjct 615 IGIMKSCRHQNIIDYIDSYLVGD----SLWVAMEFMGGGCLTEILEQFNSVKLVEAQIAY 670
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
+ +G+AY+H+QH IHRD+ + N+LL +D VK+ DFG A + + + RV G
Sbjct 671 VCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAAQLTKSKQ-KRVTIVGT 729
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQMTV 1121
+W APE ++ + D+WS G+ E+ S PP + L LI T
Sbjct 730 P--YWMAPELIRGQNYDRKVDIWSLGIMAMEMAESEPPYMSFPPLRALFLI-------TT 780
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKT 1171
+ +L ++ +K + +K C + + RP + L+ P LKT
Sbjct 781 KGIPDLKDQ-------NKWSDDFKDFVKKCLDKDVENRPEAKVLLNHPFLKT 825
Score = 35.0 bits (79), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 29/111 (26%), Positives = 52/111 (47%), Gaps = 14/111 (13%)
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREER 772
V + L+Y+ +++ +H ++ NILL G+ +KL+D G S+++R
Sbjct 671 VCAETLKGLAYIHSQHRIHRDIKSDNILL-------GSDGSVKLADFGYAAQLTKSKQKR 723
Query 773 VERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
V + W+APE + G + +D W G +E+ + E P S P
Sbjct 724 VTIVGTPYWMAPELIRG--QNYDRKVDIWSLGIMAMEMA-ESEPPYMSFPP 771
>sp|Q92918|M4K1_HUMAN Mitogen-activated protein kinase kinase
kinase kinase 1 OS=Homo sapiens OX=9606 GN=MAP4K1 PE=1 SV=1
Length=833
Score = 90.9 bits (224), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 63/214 (29%), Positives = 112/214 (52%), Gaps = 17/214 (8%)
Query 888 DPTVFHKR---YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
DP +F++ + ++ LG G +G+V + + +G++VA+K +K + S
Sbjct 5 DPDIFNRDPRDHYDLLQRLGGGTYGEV----FKARDKVSGDLVALKMVKMEPD-DDVSTL 59
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLF 1003
++EI IL+T H +I+ Y G + L + ME+ GSL+D Y S+ Q+
Sbjct 60 QKEILILKTCRHANIVAYHGSY--LWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYV 117
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+++ +G+AYLH+Q IHRD+ N+L+++ V++ DFG++ + G R +
Sbjct 118 CREVLQGLAYLHSQKKIHRDIKGANILINDAGEVRLADFGISAQI--GATLARRLSFIGT 175
Query 1064 PVFWYAPECLK---EYKFYYASDVWSFGVTLYEL 1094
P +W APE + + D+WS G+T EL
Sbjct 176 P-YWMAPEVAAVALKGGYNELCDIWSLGITAIEL 208
Score = 42.7 bits (99), Expect = 0.025, Method: Compositional matrix adjust.
Identities = 55/236 (23%), Positives = 94/236 (40%), Gaps = 45/236 (19%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
F+R + L LG GT V++ R +V G V
Sbjct 9 FNRDPRDHYDLLQRLGGGTYGEVFKARDKVSGD------------------------LVA 44
Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWL 699
LK++ D + ++ H ++ HG + + + E+ G L D++
Sbjct 45 LKMVKMEPDDDVSTLQKEILILKTCRHANIVAYHGSYLWLQKLWICMEFCGAGSLQDIY- 103
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ G + V +++ L+YL ++ +H ++ G NIL+ G ++L+D
Sbjct 104 -QVTGSLSELQISYVCREVLQGLAYLHSQKKIHRDIKGANILINDAG-------EVRLAD 155
Query 760 PGVG--LGA-LSREERVERIP-WLAPE----CLPGGANSLSTAMDKWGFGATLLEI 807
G+ +GA L+R P W+APE L GG N L D W G T +E+
Sbjct 156 FGISAQIGATLARRLSFIGTPYWMAPEVAAVALKGGYNELC---DIWSLGITAIEL 208
>sp|Q9SR05|ANX1_ARATH Receptor-like protein kinase ANXUR1 OS=Arabidopsis
thaliana OX=3702 GN=ANX1 PE=1 SV=1
Length=850
Score = 90.9 bits (224), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 67/202 (33%), Positives = 104/202 (51%), Gaps = 21/202 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FGKV Y DGT + VAVK + Q + ++ EI++L L H+H++
Sbjct 523 IGVGGFGKV----YKGVIDGTTK-VAVKKSNPNS-EQGLNEFETEIELLSRLRHKHLVSL 576
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA--- 1016
G C++ GE + LV +Y+ G+LR++L + + + L A G+ YLH
Sbjct 577 IGYCDEGGE--MCLVYDYMAFGTLREHLYNTKKPQLTWKRRLEIAIGAARGLHYLHTGAK 634
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE---GHEYYRVREDGDSPVFWYAPECL 1073
IHRD+ N+L+D + + K+ DFGL+K P GH V+ + PE
Sbjct 635 YTIIHRDVKTTNILVDENWVAKVSDFGLSKTGPNMNGGHVTTVVK----GSFGYLDPEYF 690
Query 1074 KEYKFYYASDVWSFGVTLYELL 1095
+ + SDV+SFGV L+E+L
Sbjct 691 RRQQLTEKSDVYSFGVVLFEIL 712
Score = 43.5 bits (101), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 60/262 (23%), Positives = 102/262 (39%), Gaps = 27/262 (10%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K +P+ F L+S++ H HL + G C G E +V +Y+ G L
Sbjct 541 KVAVKKSNPNSEQGLNEFETEIELLSRLRHKHLVSLIGYCDEGGEMCLVYDYMAFGTLRE 600
Query 698 WLRRERGHVPMAWK--MVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752
L + + WK + +A A L YL ++H +V NIL+ +A+ +
Sbjct 601 HLYNTK-KPQLTWKRRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILVDENWVAKVSD 659
Query 753 PFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI----- 807
+ + P + G ++ + +L PE L+ D + FG L EI
Sbjct 660 FGLSKTGPNMNGGHVTTVVK-GSFGYLDPEYFR--RQQLTEKSDVYSFGVVLFEILCARP 716
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL------------ATLTSQCLTYEPTQ 855
+ P + S + +R+ L + P L A +CL +
Sbjct 717 ALNPSLPKEQVSLGDWAMNCKRKGNLEDIIDPNLKGKINAECLKKFADTAEKCLNDSGLE 776
Query 856 RPSFRTILRDLT-RLQPHNLAD 876
RP+ +L +L LQ AD
Sbjct 777 RPTMGDVLWNLEFALQLQETAD 798
>sp|Q1PEM5|PERK3_ARATH Proline-rich receptor-like protein kinase
PERK3 OS=Arabidopsis thaliana OX=3702 GN=PERK3 PE=2 SV=2
Length=513
Score = 89.7 bits (221), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 68/201 (34%), Positives = 100/201 (50%), Gaps = 18/201 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG V + N+ VAVK LK Q ++ E++I+ ++H +++
Sbjct 189 LGEGGFGFVYKGILNNGNE-----VAVKQLKVGSA-QGEKEFQAEVNIISQIHHRNLVSL 242
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
G C ++ LV E+VP +L +L R ++ + L A +G++YLH
Sbjct 243 VGYCIAGAQR--LLVYEFVPNNTLEFHLHGKGRPTMEWSLRLKIAVSSSKGLSYLHENCN 300
Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075
IHRD+ A N+L+D K+ DFGLAK + + + R G F Y APE
Sbjct 301 PKIIHRDIKAANILIDFKFEAKVADFGLAKIALDTNTHVSTRVMG---TFGYLAPEYAAS 357
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
K SDV+SFGV L EL+T
Sbjct 358 GKLTEKSDVYSFGVVLLELIT 378
Score = 53.9 bits (128), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 48/183 (26%), Positives = 81/183 (44%), Gaps = 27/183 (15%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F +++SQ+ H +L + G C+ G + ++V E+V + L+ L +G M W ++
Sbjct 224 FQAEVNIISQIHHRNLVSLVGYCIAGAQRLLVYEFVPNNTLEFHL-HGKGRPTMEWSLRL 282
Query 713 VVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+A + LSYL N ++H ++ NIL+ A K++D G+ AL
Sbjct 283 KIAVSSSKGLSYLHENCNPKIIHRDIKAANILIDFKFEA-------KVADFGLAKIALDT 335
Query 770 EERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
V +LAPE G L+ D + FG LLE+ + R P +
Sbjct 336 NTHVSTRVMGTFGYLAPEYAASG--KLTEKSDVYSFGVVLLEL-------ITGRRPVDAN 386
Query 825 HFY 827
+ Y
Sbjct 387 NVY 389
>sp|Q9ZT07|RKS1_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase RKS1 OS=Arabidopsis thaliana OX=3702 GN=RKS1
PE=3 SV=3
Length=833
Score = 90.9 bits (224), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 71/202 (35%), Positives = 102/202 (50%), Gaps = 18/202 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V Y E +AVK L + G Q +K E+ ++ L H ++++
Sbjct 521 LGAGGFGPV----YKGVLQNRME-IAVKRLSRNSG-QGMEEFKNEVKLISKLQHRNLVRI 574
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017
GCC + EK LV EY+P SL DY H A+L + + I G+ YLH
Sbjct 575 LGCCVELEEK--MLVYEYLPNKSL-DYFIFHEEQRAELDWPKRMEIVRGIARGILYLHQD 631
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL A N+LLD++ + KI DFG+A+ + G++ + APE
Sbjct 632 SRLRIIHRDLKASNILLDSEMIPKISDFGMAR-IFGGNQMEGCTSRVVGTFGYMAPEYAM 690
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
E +F SDV+SFGV + E++T
Sbjct 691 EGQFSIKSDVYSFGVLMLEIIT 712
Score = 50.8 bits (120), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 45/184 (24%), Positives = 81/184 (44%), Gaps = 20/184 (11%)
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+ + +K L + F L+S++ H +L + G CV E ++V EY+ +
Sbjct 536 NRMEIAVKRLSRNSGQGMEEFKNEVKLISKLQHRNLVRILGCCVELEEKMLVYEYLPNKS 595
Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAE 749
LD ++ E + W +M + + +A + YL + ++H ++ NILL
Sbjct 596 LDYFIFHEEQRAELDWPKRMEIVRGIARGILYLHQDSRLRIIHRDLKASNILL------- 648
Query 750 GTSPFIKLSDPGVG--LGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGAT 803
+ K+SD G+ G E R+ ++APE G S+ + D + FG
Sbjct 649 DSEMIPKISDFGMARIFGGNQMEGCTSRVVGTFGYMAPEYAMEGQFSIKS--DVYSFGVL 706
Query 804 LLEI 807
+LEI
Sbjct 707 MLEI 710
>sp|P53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 OS=Homo
sapiens OX=9606 GN=PLK1 PE=1 SV=1
Length=603
Score = 90.1 bits (222), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 77/267 (29%), Positives = 118/267 (44%), Gaps = 28/267 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960
LG+G F K C++ ++ T E+ A K + P R EI I R+L H+H++
Sbjct 59 LGKGGFAK----CFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVV 114
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G ED + +V+E SL + + R ++ + + +QI G YLH
Sbjct 115 GFHGFFEDND--FVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRV 172
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRDL N+ L+ D VKIGDFGLA V E R + +P + APE L +
Sbjct 173 IHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGE--RKKTLCGTPN-YIAPEVLSKKGHS 229
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+ DVWS G +Y L L+G + + L+ T L + P
Sbjct 230 FEVDVWSIGCIMYTL----------------LVGKPPFETSCLKETYLRIKKNEYSIPKH 273
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLI 1166
L++ +T+ + RPT L+
Sbjct 274 INPVAASLIQKMLQTDPTARPTINELL 300
Score = 43.9 bits (102), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 46/211 (22%), Positives = 84/211 (40%), Gaps = 16/211 (8%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+ ++H H+ HG +V E L + L + R + +Q+
Sbjct 103 SIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSL-LELHKRRKALTEPEARYYLRQIV 161
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776
YL ++H R++ L L L E +K+ D G+ ER + +
Sbjct 162 LGCQYLHRNRVIH-----RDLKLGNLFLNEDLE--VKIGDFGLATKVEYDGERKKTLCGT 214
Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLP 834
++APE L +S +D W G + + G+ P ++ E + ++ +P
Sbjct 215 PNYIAPEVLSKKGHSFE--VDVWSIGCIMYTLLV-GKPPFETSCLKETYLRIKKNEYSIP 271
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ P A+L + L +PT RP+ +L D
Sbjct 272 KHINPVAASLIQKMLQTDPTARPTINELLND 302
>sp|Q54U31|SHKD_DICDI Dual specificity protein kinase shkD OS=Dictyostelium
discoideum OX=44689 GN=shkD PE=3 SV=1
Length=744
Score = 90.5 bits (223), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 73/290 (25%), Positives = 128/290 (44%), Gaps = 29/290 (10%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQH 940
P AS P + + LG+G FG V G+ VAVK K
Sbjct 262 PKRKASGPPEILPEEIDRTDFLGQGSFGSVY------KGKCRGQEVAVKIPRKQKLSLYE 315
Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS---LRDYLPRHSIGL 997
+ ++ E+ I+ ++H +++ + G C G+ +Q+V E L + + L
Sbjct 316 LTSFRHEVKIMSKIFHPNVVLFLGACTQSGK--MQIVTELCQTDLEKLLHNDRTKKEFSL 373
Query 998 AQLLLFAQQICEGMAYLHA-QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
+ + A+ GM +LH +H DL N+L+D + VK+ DFG ++ + EG E+
Sbjct 374 FRRMQMAKDAALGMNWLHGITRIVHNDLKTANLLVDINLRVKVTDFGFSQ-IKEGEEFQD 432
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
G +P+ W APE + + +DV+SFG+ L+E+LT ++P +
Sbjct 433 KAAKG-TPL-WMAPEVMMGNPYNEKADVYSFGIILWEILT----KEAP---------YSH 477
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ + + ER P P + HL++ CW+ RP+F ++
Sbjct 478 HKDYDIFFNAICNEKERPPIPADTLPSLRHLIQTCWDHNPQNRPSFSEIL 527
Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 74/300 (25%), Positives = 126/300 (42%), Gaps = 58/300 (19%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+EI + LGQG+ +VY+G+ R GQE+ V + P
Sbjct 275 EEIDRTDFLGQGSFGSVYKGKCR------------------------GQEVAVKI----P 306
Query 647 SHHDIAL----AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
++L +F +MS++ H ++ G C + + +VTE + L+ L +
Sbjct 307 RKQKLSLYELTSFRHEVKIMSKIFHPNVVLFLGACTQSGKMQIVTELCQTD-LEKLLHND 365
Query 703 RGHVPMAW--KMVVAQQLASALSYLEN-KNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R + +M +A+ A +++L +VH ++ N LL + L +K++D
Sbjct 366 RTKKEFSLFRRMQMAKDAALGMNWLHGITRIVHNDLKTAN-LLVDINLR------VKVTD 418
Query 760 PG---VGLGALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G + G +++ + P W+APE + G N + D + FG L EI EAP
Sbjct 419 FGFSQIKEGEEFQDKAAKGTPLWMAPEVMMG--NPYNEKADVYSFGIILWEI-LTKEAPY 475
Query 816 QSRSPSEKEHFYQ----RQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + F+ + R P P + P L L C + P RPSF IL L +
Sbjct 476 SHHK--DYDIFFNAICNEKERPPIPADTLPSLRHLIQTCWDHNPQNRPSFSEILFRLNEI 533
>sp|Q9VI13|PAK_DROME Serine/threonine-protein kinase Pak OS=Drosophila
melanogaster OX=7227 GN=Pak PE=1 SV=1
Length=704
Score = 90.5 bits (223), Expect = 4e-17, Method: Compositional matrix adjust.
Identities = 60/203 (30%), Positives = 97/203 (48%), Gaps = 12/203 (6%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
R K+ +G+G G V Y TG VA+K + P+ + EI ++R
Sbjct 427 NRKYTKMEKIGQGASGTV----YTAIESSTGMEVAIKQMNLSQQPK-KELIINEILVMRE 481
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013
H +++ Y E L +VMEY+P GSL D + + Q+ +++ + + +
Sbjct 482 NKHPNVVNYLDSYLVSEE--LWVVMEYLPGGSLTDVVTETCMDEGQIAAVCREVLQALEF 539
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
LHA IHRD+ + N+LL D VK+ DFG A+ PE + R G +W APE
Sbjct 540 LHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPE--QSKRTTMVGTP--YWMAPEV 595
Query 1073 LKEYKFYYASDVWSFGVTLYELL 1095
+ ++ D+WS G+ E++
Sbjct 596 VTRKQYGPKVDLWSLGIMAIEMV 618
>sp|Q9SFX0|PBL22_ARATH Probable serine/threonine-protein kinase
PBL22 OS=Arabidopsis thaliana OX=3702 GN=PBL22 PE=2 SV=1
Length=381
Score = 88.2 bits (217), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 82/277 (30%), Positives = 131/277 (47%), Gaps = 25/277 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FG V Y D +G++VA+K L D G Q + E+ +L +H +++
Sbjct 81 IGKGGFGSV----YKGRLD-SGQVVAIKQLNPD-GHQGNQEFIVEVCMLSVFHHPNLVTL 134
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHS-IGLAQLLLFAQQICEGMAYLHAQ 1017
G C ++ LV EY+P+GSL D+L P + + + A G+ YLH +
Sbjct 135 IGYCTSGAQR--LLVYEYMPMGSLEDHLFDLEPDQTPLSWYTRMKIAVGAARGIEYLHCK 192
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
I+RDL + N+LLD + VK+ DFGLAK P G+ + V + APE
Sbjct 193 ISPSVIYRDLKSANILLDKEFSVKLSDFGLAKVGPVGNRTH-VSTRVMGTYGYCAPEYAM 251
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLR----LTELLE 1129
+ SD++SFGV L EL++ + S P L+ A+ + + L + L
Sbjct 252 SGRLTIKSDIYSFGVVLLELISGRKAIDLSKPNGEQYLVAWARPYLKDPKKFGLLVDPLL 311
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
RG+ R C + + C EA+ RP +++
Sbjct 312 RGKFSKR---CLNYAISITEMCLNDEANHRPKIGDVV 345
Score = 56.6 bits (135), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 81/345 (23%), Positives = 134/345 (39%), Gaps = 69/345 (20%)
Query 553 PQPGETSNLIIMRGARASP------RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606
P+ + + I++ G SP R+ +L+ K + + +G+G +VY+G
Sbjct 36 PRGTGSKSGILVNGKVNSPKPGGGARSFTFKELA---AATKNFREGNIIGKGGFGSVYKG 92
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS 666
RL D GQ V +K L+P H F ++S
Sbjct 93 RL-----------------------DSGQV--VAIKQLNPDGHQGNQEFIVEVCMLSVFH 127
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAW--KMVVAQQLASALS 723
H +L + G C G + ++V EY+ G L D E P++W +M +A A +
Sbjct 128 HPNLVTLIGYCTSGAQRLLVYEYMPMGSLEDHLFDLEPDQTPLSWYTRMKIAVGAARGIE 187
Query 724 YLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERVE-RIPW 778
YL K ++++ ++ NILL + +KLSD G+ +G + V R+
Sbjct 188 YLHCKISPSVIYRDLKSANILLDK-------EFSVKLSDFGLAKVGPVGNRTHVSTRVMG 240
Query 779 LAPECLPGGANS--LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836
C P A S L+ D + FG LLE+ +A S+ E+ + L +P
Sbjct 241 TYGYCAPEYAMSGRLTIKSDIYSFGVVLLELISGRKAIDLSKPNGEQYLVAWARPYLKDP 300
Query 837 S-----------------CPQLA-TLTSQCLTYEPTQRPSFRTIL 863
C A ++T CL E RP ++
Sbjct 301 KKFGLLVDPLLRGKFSKRCLNYAISITEMCLNDEANHRPKIGDVV 345
>sp|Q96PY6|NEK1_HUMAN Serine/threonine-protein kinase Nek1 OS=Homo
sapiens OX=9606 GN=NEK1 PE=1 SV=2
Length=1258
Score = 90.9 bits (224), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 57/201 (28%), Positives = 102/201 (51%), Gaps = 11/201 (5%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+++ +GEG FGK L T DG ++ + + + R ++E+ +L + H +
Sbjct 6 RLQKIGEGSFGKAILV--KSTEDGRQYVIKEINI-SRMSSKEREESRREVAVLANMKHPN 62
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLH 1015
I++Y+ E+ G SL +VM+Y G L + L Q+L + QIC + ++H
Sbjct 63 IVQYRESFEENG--SLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH 120
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ +HRD+ ++N+ L D V++GDFG+A+ + E R ++ +PE +
Sbjct 121 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELART---CIGTPYYLSPEICEN 177
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
+ SD+W+ G LYEL T
Sbjct 178 KPYNNKSDIWALGCVLYELCT 198
>sp|P97377|CDK2_MOUSE Cyclin-dependent kinase 2 OS=Mus musculus
OX=10090 GN=Cdk2 PE=1 SV=2
Length=346
Score = 87.8 bits (216), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 65/207 (31%), Positives = 101/207 (49%), Gaps = 15/207 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955
+K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ L
Sbjct 4 FQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYV--PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013
H +I+K E L LV E++ L D I L + + Q+ +G+A+
Sbjct 60 HPNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAF 117
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072
H+ +HRDL +N+L++ + +K+ DFGLA+A Y + WY APE
Sbjct 118 CHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTY----THEVVTLWYRAPEI 173
Query 1073 LKEYKFY-YASDVWSFGVTLYELLTHC 1098
L K+Y A D+WS G E+ C
Sbjct 174 LLGCKYYSTAVDIWSLGCIFAEMHLVC 200
Score = 33.9 bits (76), Expect = 8.3, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 12/95 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREER 772
QL L++ + ++H ++ +N+L+ AEG+ IKL+D G+ G+ +
Sbjct 110 QLLQGLAFCHSHRVLHRDLKPQNLLIN----AEGS---IKLADFGLARAFGVPVRTYTHE 162
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
V + + APE L G STA+D W G E+
Sbjct 163 VVTLWYRAPEILLG-CKYYSTAVDIWSLGCIFAEM 196
>sp|B4GBH0|PTK7_DROPE Tyrosine-protein kinase-like otk OS=Drosophila
persimilis OX=7234 GN=otk PE=3 SV=1
Length=1035
Score = 90.9 bits (224), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 65/255 (25%), Positives = 120/255 (47%), Gaps = 30/255 (12%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY G
Sbjct 783 QLVLVKALNKVKDEQACQEFRRQLDLLRGISHKGVVRLFGLCREKDPH--YMVLEYTDWG 840
Query 985 SLRDYLPRHS--------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030
L+ +L + + +Q+L A QI GM ++ HRDLA RN +
Sbjct 841 DLKQFLLATAGKVNTATATSSPPALTTSQVLAVAYQIARGMDAIYRSRCTHRDLATRNCV 900
Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
+ ++ +VK+ L K EY++ R + PV W APEC++E ++ SD++++GV
Sbjct 901 ISSEFVVKVSYPALCKD-KYSREYHKHR-NTLLPVRWLAPECIQEDEYTTKSDIFAYGVL 958
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
++EL +++ P + I + Q L T + P + ++ +
Sbjct 959 VWELFNQ--ATKLPHEELTSEQVIQRSQAGTLEWT----------VAEATPDSLKEILLS 1006
Query 1151 CWETEASFRPTFENL 1165
CW RP+F L
Sbjct 1007 CWLANPKERPSFSQL 1021
Score = 53.1 bits (126), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 61/260 (23%), Positives = 103/260 (40%), Gaps = 41/260 (16%)
Query 636 ELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
E V++K L+ + A F L+ +SH + + G+C + MV EY + G
Sbjct 782 EQLVLVKALNKVKDEQACQEFRRQLDLLRGISHKGVVRLFGLCREKDPHYMVLEYTDWGD 841
Query 695 LDVWLRRERGHVPMAWK------------MVVAQQLASALSYLENKNLVHGNVCGRNILL 742
L +L G V A + VA Q+A + + H ++ RN ++
Sbjct 842 LKQFLLATAGKVNTATATSSPPALTTSQVLAVAYQIARGMDAIYRSRCTHRDLATRNCVI 901
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDK 797
+ + +K+S P + SRE R + WLAPEC+ + +T D
Sbjct 902 S-------SEFVVKVSYPALCKDKYSREYHKHRNTLLPVRWLAPECIQ--EDEYTTKSDI 952
Query 798 WGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQH------RLPEPSCPQLATLTSQC 848
+ +G + E+ F+ L P E+ E QR + E + L + C
Sbjct 953 FAYGVLVWEL-FNQATKL----PHEELTSEQVIQRSQAGTLEWTVAEATPDSLKEILLSC 1007
Query 849 LTYEPTQRPSFRTILRDLTR 868
P +RPSF + L++
Sbjct 1008 WLANPKERPSFSQLGSALSK 1027
>sp|F4JZW1|PBL13_ARATH Serine/threonine-protein kinase PBL13 OS=Arabidopsis
thaliana OX=3702 GN=PBL13 PE=1 SV=1
Length=494
Score = 89.4 bits (220), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 78/203 (38%), Positives = 102/203 (50%), Gaps = 15/203 (7%)
Query 903 LGEGHFGKVSL-YCYDPTNDG-TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LGEG FG V + D G + VAVK L D HR + E+ L L H +++
Sbjct 82 LGEGGFGPVHKGFIDDKLRPGLKAQPVAVKLLDLDGLQGHRE-FMTEVMCLGKLKHPNLV 140
Query 961 KYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGL--AQLLLFAQQICEGMAYLHA 1016
K G CCE E LV E++P GSL L R S+ L L A + +G+ +LH
Sbjct 141 KLIGYCCE---EAHRLLVYEFMPRGSLESQLFRRCSLPLPWTTRLNIAYEAAKGLQFLHE 197
Query 1017 QH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE-YYRVREDGDSPVFWYAPECL 1073
I+RD A N+LLD+D K+ DFGLAK P+G + + R G + APE +
Sbjct 198 AEKPIIYRDFKASNILLDSDYTAKLSDFGLAKDGPQGDDTHVSTRVMGTQG--YAAPEYI 255
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
SDV+SFGV L ELLT
Sbjct 256 MTGHLTAKSDVYSFGVVLLELLT 278
Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 73/290 (25%), Positives = 118/290 (41%), Gaps = 45/290 (16%)
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
G G +G +DD+ L PG + Q V +K+LD F + ++ H +L
Sbjct 86 GFGPVHKGFIDDK--LRPGL-KAQP--VAVKLLDLDGLQGHREFMTEVMCLGKLKHPNLV 140
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN-- 727
+ G C ++V E++ G L+ L R R +P+ W ++ +A + A L +L
Sbjct 141 KLIGYCCEEAHRLLVYEFMPRGSLESQLFR-RCSLPLPWTTRLNIAYEAAKGLQFLHEAE 199
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVE-RI----PWLAP 781
K +++ + NILL A KLSD G+ G + V R+ + AP
Sbjct 200 KPIIYRDFKASNILLDSDYTA-------KLSDFGLAKDGPQGDDTHVSTRVMGTQGYAAP 252
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ------------- 828
E + G L+ D + FG LLE+ G + S KE +
Sbjct 253 EYIMTG--HLTAKSDVYSFGVVLLEL-LTGRKSVDIARSSRKETLVEWARPMLNDARKLG 309
Query 829 ------RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
+ + E + ATL QCL Y P RP T++ L ++ +
Sbjct 310 RIMDPRLEDQYSETGARKAATLAYQCLRYRPKTRPDISTVVSVLQDIKDY 359
>sp|G5EFU0|PK2_CAEEL Serine/threonine-protein kinase pak-2 OS=Caenorhabditis
elegans OX=6239 GN=pak-2 PE=2 SV=1
Length=522
Score = 89.4 bits (220), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 60/199 (30%), Positives = 97/199 (49%), Gaps = 10/199 (5%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L + +GEG G V T ++VAVK + Q R E+ ILR H
Sbjct 231 LTDYKQIGEGSTGVVEAAY----KISTKQIVAVKRMNLRKQ-QRRELLFNEVSILRQYQH 285
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016
+I+++ E L +VME++ GSL D + + Q+ ++Q+ + +LHA
Sbjct 286 PNIVRFFSSHLVDDE--LWVVMEFMEGGSLTDIVTATRMTEPQIATISRQVLGALDFLHA 343
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ IHRD+ + ++LL D VK+ DFG + E E R R +P +W A E +
Sbjct 344 RKVIHRDIKSDSILLKRDGTVKLTDFGFCGQLSE--EVPRRRSLVGTP-YWTAAEVIARE 400
Query 1077 KFYYASDVWSFGVTLYELL 1095
+ +D+WSFG+ L E++
Sbjct 401 PYDTRADIWSFGIMLIEMV 419
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/223 (25%), Positives = 93/223 (42%), Gaps = 30/223 (13%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
+ S++ Q H ++ + E +V E++E G L + R P +
Sbjct 273 LFNEVSILRQYQHPNIVRFFSSHLVDDELWVVMEFMEGGSLTDIVTATRMTEPQI--ATI 330
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
++Q+ AL +L + ++H ++ +ILL R G +KL+D G G LS E
Sbjct 331 SRQVLGALDFLHARKVIHRDIKSDSILLKRDGT-------VKLTDFGF-CGQLSEEVPRR 382
Query 775 R----IP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP--------S 821
R P W A E + T D W FG L+E+ +GE P + P
Sbjct 383 RSLVGTPYWTAAEVI--AREPYDTRADIWSFGIMLIEMV-EGEPPFFNDQPFQAMKRIRD 439
Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
E E + R ++ +L+ L S C+ + +R + +LR
Sbjct 440 EHEARFSRHAKV----SVELSELLSHCIVKDVNKRWPAKDLLR 478
>sp|Q9M2Z1|BAME2_ARATH Leucine-rich repeat receptor-like serine/threonine-protein
kinase BAM2 OS=Arabidopsis thaliana OX=3702
GN=BAM2 PE=1 SV=1
Length=1002
Score = 90.5 bits (223), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 82/272 (30%), Positives = 127/272 (47%), Gaps = 42/272 (15%)
Query 924 GEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982
G++VAVK L G H G+ EI L + H HI++ G C + E +L LV EY+P
Sbjct 712 GDLVAVKRLATMSHGSSHDHGFNAEIQTLGRIRHRHIVRLLGFCSNH-ETNL-LVYEYMP 769
Query 983 LGSLRDYL-----------PRHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARN 1028
GSL + L R+ I L + +G+ YLH + +HRD+ + N
Sbjct 770 NGSLGEVLHGKKGGHLHWNTRYKIAL--------EAAKGLCYLHHDCSPLIVHRDVKSNN 821
Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
+LLD++ + DFGLAK + + + S + APE K SDV+SFG
Sbjct 822 ILLDSNFEAHVADFGLAKFLQDSGTSECMSAIAGS-YGYIAPEYAYTLKVDEKSDVYSFG 880
Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQ--------GQMTVLRLTELLERGERLPRPDKC 1140
V L EL+T + P +F + + I Q + VL++ +L R +P +
Sbjct 881 VVLLELIT----GKKPVGEFGDGVDIVQWVRSMTDSNKDCVLKVIDL--RLSSVPVHEV- 933
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
V+++ C E +A RPT ++ IL +
Sbjct 934 -THVFYVALLCVEEQAVERPTMREVVQILTEI 964
Score = 43.9 bits (102), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 57/247 (23%), Positives = 104/247 (42%), Gaps = 45/247 (18%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKM 712
F + ++ H H+ + G C N++V EY+ +G L +V ++ GH+ +
Sbjct 732 GFNAEIQTLGRIRHRHIVRLLGFCSNHETNLLVYEYMPNGSLGEVLHGKKGGHLHWNTRY 791
Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPG 761
+A + A L YL + +VH +V NILL A GLA+ F++ S
Sbjct 792 KIALEAAKGLCYLHHDCSPLIVHRDVKSNNILLDSNFEAHVADFGLAK----FLQDSGTS 847
Query 762 VGLGALSREERVERIPWLAPECLPGGANSLST--AMDKWGFGATLLEICFDGEAP----- 814
+ A++ ++APE A +L D + FG LLE+ G+ P
Sbjct 848 ECMSAIAGS-----YGYIAPEY----AYTLKVDEKSDVYSFGVVLLEL-ITGKKPVGEFG 897
Query 815 --------LQSRSPSEKEHFYQ----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
++S + S K+ + R +P + + C+ + +RP+ R +
Sbjct 898 DGVDIVQWVRSMTDSNKDCVLKVIDLRLSSVPVHEVTHVFYVALLCVEEQAVERPTMREV 957
Query 863 LRDLTRL 869
++ LT +
Sbjct 958 VQILTEI 964
>sp|O14299|WIS4_SCHPO MAP kinase kinase kinase wis4 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=wis4
PE=3 SV=1
Length=1401
Score = 90.9 bits (224), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 85/279 (30%), Positives = 128/279 (46%), Gaps = 40/279 (14%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD- 902
L+ Q L E R I R+ T L+ + VL D +VF R K+
Sbjct 979 LSIQLLQKETMLRIDELEIERNNTLLERLAIGHVL---------DDSVFRNRDFIKLASS 1029
Query 903 -------LGEGHFGKVSLY--CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---EIDI 950
+GHF + ++ Y N TG+++AVK +K RS Q E+ +
Sbjct 1030 FSNITIRWQQGHFVRSGMFGDVYTGVNMETGDLLAVKEIKLQDSRTFRSTVDQIHNEMTV 1089
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL-LFAQQICE 1009
L L H +++ Y G E EK + + ME+ GSL D L I +L ++ Q+ E
Sbjct 1090 LERLNHPNVVTYYGV-EVHREK-VYIFMEFCQGGSLADLLAHGRIEDENVLKVYVVQLLE 1147
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV--PEGHEYYRVREDGDSPVF- 1066
G+AY+H+QH +HRD+ N+LLD+ ++K DFG A V P E VR + P
Sbjct 1148 GLAYIHSQHILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPE---VRYEDIQPELQ 1204
Query 1067 -------WYAPECLKEYKF--YYASDVWSFGVTLYELLT 1096
+ APE + K + A D+WS G + E++T
Sbjct 1205 HLAGTPMYMAPEIILGTKKGDFGAMDIWSLGCVILEMMT 1243
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 68/266 (26%), Positives = 109/266 (41%), Gaps = 41/266 (15%)
Query 614 GDPEEG-KMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672
GD G M+ D L + Q+ R +D H+++ +++ +++H ++
Sbjct 1049 GDVYTGVNMETGDLLAVKEIKLQDSRTFRSTVDQIHNEM--------TVLERLNHPNVVT 1100
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVH 732
+GV V + + E+ + G L L R K+ V Q L L+Y+ +++++H
Sbjct 1101 YYGVEVHREKVYIFMEFCQGGSLADLLAHGRIEDENVLKVYVVQ-LLEGLAYIHSQHILH 1159
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA---LSREERVERIP-----------W 778
++ NILL G+ IK SD G L E R E I +
Sbjct 1160 RDIKPANILLDHRGM-------IKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAGTPMY 1212
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838
+APE + G AMD W G +LE+ G P S +E Y + PS
Sbjct 1213 MAPEIILGTKKGDFGAMDIWSLGCVILEM-MTGSTPW-SEMDNEWAIMYHVA-AMHTPSI 1269
Query 839 PQLATLTS-------QCLTYEPTQRP 857
PQ ++S QC +P QRP
Sbjct 1270 PQNEKISSLARDFIEQCFERDPEQRP 1295
>sp|Q7ZZC8|NEK9_XENLA Serine/threonine-protein kinase Nek9 OS=Xenopus
laevis OX=8355 GN=nek9 PE=2 SV=1
Length=944
Score = 90.5 bits (223), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 80/277 (29%), Positives = 128/277 (46%), Gaps = 30/277 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEH 958
IR LG G +G+ +LY T D + +V K + A + R EI IL L H++
Sbjct 37 IRVLGHGAYGEATLY--RRTEDDS--LVVWKEVGLARLSEKERRDALNEIVILSLLQHDN 92
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMAYLH 1015
II Y D +L + +EY G+L D + L Q +L + QI ++ +H
Sbjct 93 IIAYYNHFLDS--NTLLIELEYCNGGNLFDKIVHQKAQLFQEETVLWYLFQIVSAVSCIH 150
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRD+ N+ L L+K+GD+GLAK + Y + E +++ +PE +
Sbjct 151 KAGILHRDIKTLNIFLTKANLIKLGDYGLAKQLS---SEYSMAETCVGTLYYMSPEICQG 207
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL-IGIAQGQMTVLRLTELLERGERL 1134
K+ + SD+W+ G LYELLT + + T L L + I QG V + +
Sbjct 208 VKYSFKSDIWAVGCVLYELLTLTRTFDA--TNPLNLCVKIVQGNWAVGLDNTVYTQ---- 261
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PIL 1169
E+ ++ C E + RPT + ++ PIL
Sbjct 262 --------ELIEVVHACLEQDPEKRPTADEILERPIL 290
>sp|E9PTG8|STK10_RAT Serine/threonine-protein kinase 10 OS=Rattus
norvegicus OX=10116 GN=Stk10 PE=1 SV=1
Length=967
Score = 90.5 bits (223), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 60/200 (30%), Positives = 104/200 (52%), Gaps = 17/200 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+LG+G FGKV Y N TG + A K ++ + + EI+IL T H +I+K
Sbjct 41 ELGDGAFGKV----YKAKNKETGALAAAKVIETK-SEEELEDYIVEIEILATCDHPYIVK 95
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019
G G+ L +++E+ P G++ + GL Q+ + +Q+ E + +LH +
Sbjct 96 LLGAYYYDGK--LWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRI 153
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP-----ECLK 1074
IHRDL A NVL+ + +++ DFG++ + + + R+ +W AP E +K
Sbjct 154 IHRDLKAGNVLMTLEGDIRLADFGVS---AKNLKTLQKRDSFIGTPYWMAPEVVLCETMK 210
Query 1075 EYKFYYASDVWSFGVTLYEL 1094
+ + Y +D+WS G+TL E+
Sbjct 211 DAPYDYKADIWSLGITLIEM 230
Score = 40.8 bits (94), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 30/103 (29%), Positives = 47/103 (46%), Gaps = 14/103 (14%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV---GLGALSR 769
VV +Q+ AL++L K ++H ++ N+L+ G I+L+D GV L L +
Sbjct 136 VVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEG-------DIRLADFGVSAKNLKTLQK 188
Query 770 EERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808
+ P W+APE C D W G TL+E+
Sbjct 189 RDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWSLGITLIEMA 231
>sp|Q9FN94|RLK0_ARATH Receptor-like protein kinase At5g59670 OS=Arabidopsis
thaliana OX=3702 GN=At5g59670 PE=1 SV=1
Length=868
Score = 90.5 bits (223), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 93/327 (28%), Positives = 145/327 (44%), Gaps = 27/327 (8%)
Query 856 RPSFRTILRDLTRLQPH-NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
R TI++ L RL P ++ DV N S + + R LG+G FG V
Sbjct 523 RKKMSTIVKGL-RLPPRTSMVDVTFSNKKSKRFTYSEVVQVTKNFQRVLGKGGFGMV--- 578
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG-CCEDQGEKS 973
Y T G+ E VAVK L + Q +K E+D+L ++H +++ G CCE
Sbjct 579 -YHGTVKGS-EQVAVKVL-SQSSTQGSKEFKAEVDLLLRVHHTNLVSLVGYCCEGD---Y 632
Query 974 LQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAA 1026
L LV E++P G L+ +L I + L A + G+ YLH +HRD+
Sbjct 633 LALVYEFLPNGDLKQHLSGKGGNSIINWSIRLRIALEAALGLEYLHIGCTPPMVHRDVKT 692
Query 1027 RNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
N+LLD + K+ DFGL+++ EG G + + PEC + SDV+
Sbjct 693 ANILLDENFKAKLADFGLSRSFQGEGESQESTTIAG--TLGYLDPECYHSGRLGEKSDVY 750
Query 1086 SFGVTLYELLTH--CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE 1143
SFG+ L E++T+ + S + + +G QM + E+++ R
Sbjct 751 SFGIVLLEMITNQPVINQTSGDSHITQWVGF---QMNRGDILEIMDPNLRKDYNINSAWR 807
Query 1144 VYHLMKNCWETEASFRPTFENLIPILK 1170
L +C +S RP+ +I LK
Sbjct 808 ALELAMSCAYPSSSKRPSMSQVIHELK 834
Score = 54.7 bits (130), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 70/265 (26%), Positives = 105/265 (40%), Gaps = 54/265 (20%)
Query 563 IMRGARASPRT----LNLSQLSFHRVDQKEITQLSH-----LGQGTRTNVYEGRLRVEGS 613
I++G R PRT + S R E+ Q++ LG+G VY G ++
Sbjct 529 IVKGLRLPPRTSMVDVTFSNKKSKRFTYSEVVQVTKNFQRVLGKGGFGMVYHGTVK---- 584
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
G E +V +KVL S + F L+ +V HT+L +
Sbjct 585 --------------------GSE-QVAVKVLSQSSTQGSKEFKAEVDLLLRVHHTNLVSL 623
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NK 728
G C G +V E++ +G L L + G+ + W ++ +A + A L YL
Sbjct 624 VGYCCEGDYLALVYEFLPNGDLKQHLSGKGGNSIINWSIRLRIALEAALGLEYLHIGCTP 683
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPE 782
+VH +V NILL A KL+D G+ E E + +L PE
Sbjct 684 PMVHRDVKTANILLDENFKA-------KLADFGLSRSFQGEGESQESTTIAGTLGYLDPE 736
Query 783 CLPGGANSLSTAMDKWGFGATLLEI 807
C G L D + FG LLE+
Sbjct 737 CYHSG--RLGEKSDVYSFGIVLLEM 759
>sp|O55098|STK10_MOUSE Serine/threonine-protein kinase 10 OS=Mus
musculus OX=10090 GN=Stk10 PE=1 SV=2
Length=966
Score = 90.5 bits (223), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 60/200 (30%), Positives = 104/200 (52%), Gaps = 17/200 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+LG+G FGKV Y N TG + A K ++ + + EI+IL T H +I+K
Sbjct 41 ELGDGAFGKV----YKAKNKETGALAAAKVIETK-SEEELEDYIVEIEILATCDHPYIVK 95
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019
G G+ L +++E+ P G++ + GL Q+ + +Q+ E + +LH +
Sbjct 96 LLGAYYYDGK--LWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRI 153
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP-----ECLK 1074
IHRDL A NVL+ + +++ DFG++ + + + R+ +W AP E +K
Sbjct 154 IHRDLKAGNVLMTLEGDIRLADFGVS---AKNLKTLQKRDSFIGTPYWMAPEVVLCETMK 210
Query 1075 EYKFYYASDVWSFGVTLYEL 1094
+ + Y +D+WS G+TL E+
Sbjct 211 DAPYDYKADIWSLGITLIEM 230
Score = 40.8 bits (94), Expect = 0.094, Method: Compositional matrix adjust.
Identities = 30/103 (29%), Positives = 47/103 (46%), Gaps = 14/103 (14%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV---GLGALSR 769
VV +Q+ AL++L K ++H ++ N+L+ G I+L+D GV L L +
Sbjct 136 VVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEG-------DIRLADFGVSAKNLKTLQK 188
Query 770 EERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808
+ P W+APE C D W G TL+E+
Sbjct 189 RDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWSLGITLIEMA 231
>sp|Q290N5|PTK7_DROPS Tyrosine-protein kinase-like otk OS=Drosophila
pseudoobscura pseudoobscura OX=46245 GN=otk PE=3 SV=2
Length=1037
Score = 90.5 bits (223), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 65/255 (25%), Positives = 120/255 (47%), Gaps = 30/255 (12%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY G
Sbjct 785 QLVLVKALNKVKDEQACQEFRRQLDLLRGISHKGVVRLFGLCREKDPH--YMVLEYTDWG 842
Query 985 SLRDYLPRHS--------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030
L+ +L + + +Q+L A QI GM ++ HRDLA RN +
Sbjct 843 DLKQFLLATAGKVNTATATSSPPALTTSQVLAVAYQIARGMDAIYRSRCTHRDLATRNCV 902
Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
+ ++ +VK+ L K EY++ R + PV W APEC++E ++ SD++++GV
Sbjct 903 ISSEFVVKVSYPALCKD-KYSREYHKHR-NTLLPVRWLAPECIQEDEYTTKSDIFAYGVL 960
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
++EL +++ P + I + Q L T + P + ++ +
Sbjct 961 VWELFNQ--ATKLPHEELTSEQVIQRSQAGTLEWT----------VAEATPDSLKEILLS 1008
Query 1151 CWETEASFRPTFENL 1165
CW RP+F L
Sbjct 1009 CWLANPKERPSFSQL 1023
Score = 53.1 bits (126), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 61/260 (23%), Positives = 103/260 (40%), Gaps = 41/260 (16%)
Query 636 ELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
E V++K L+ + A F L+ +SH + + G+C + MV EY + G
Sbjct 784 EQLVLVKALNKVKDEQACQEFRRQLDLLRGISHKGVVRLFGLCREKDPHYMVLEYTDWGD 843
Query 695 LDVWLRRERGHVPMAWK------------MVVAQQLASALSYLENKNLVHGNVCGRNILL 742
L +L G V A + VA Q+A + + H ++ RN ++
Sbjct 844 LKQFLLATAGKVNTATATSSPPALTTSQVLAVAYQIARGMDAIYRSRCTHRDLATRNCVI 903
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDK 797
+ + +K+S P + SRE R + WLAPEC+ + +T D
Sbjct 904 S-------SEFVVKVSYPALCKDKYSREYHKHRNTLLPVRWLAPECIQ--EDEYTTKSDI 954
Query 798 WGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQH------RLPEPSCPQLATLTSQC 848
+ +G + E+ F+ L P E+ E QR + E + L + C
Sbjct 955 FAYGVLVWEL-FNQATKL----PHEELTSEQVIQRSQAGTLEWTVAEATPDSLKEILLSC 1009
Query 849 LTYEPTQRPSFRTILRDLTR 868
P +RPSF + L++
Sbjct 1010 WLANPKERPSFSQLGSALSK 1029
>sp|Q1RMT8|IRAK4_BOVIN Interleukin-1 receptor-associated kinase
4 OS=Bos taurus OX=9913 GN=IRAK4 PE=2 SV=1
Length=461
Score = 89.0 bits (219), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 89/306 (29%), Positives = 132/306 (43%), Gaps = 43/306 (14%)
Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP------SFRTILRDLTRLQPHNLA 875
+ E F LP+ + TL S+ Q+P +++ D Q + L
Sbjct 90 QNEFFAPASLLLPDAVPKNVNTLPSKVTVVAVQQKPKPLCGKDRTSVISDENPEQNYVLP 149
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRD----------------LGEGHFGKV-SLYCYDP 918
D + S T FH +++D +GEG FG V Y +
Sbjct 150 DSSSPENTSLEFSDTRFHSFSFFELKDVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNR 209
Query 919 TNDGTGEMVAVKALKA--DCGPQH-RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
T VAVK L A D + + + QEI ++ HE++++ G D + L
Sbjct 210 T-------VAVKKLAAMVDISTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDD--LC 260
Query 976 LVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031
LV Y+P GSL D L + AQ G++YLH H+IHRD+ + N+LL
Sbjct 261 LVYVYMPNGSLLDRLSCLDGTPPLSWNMRCKIAQGAANGLSYLHENHHIHRDIKSANILL 320
Query 1032 DNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
D D KI DFGLA+A + R G + + APE L+ + SD++SFGV
Sbjct 321 DEDFTAKISDFGLARASEKFAQTVMTSRIVGTTA--YMAPEALRG-EITPKSDIYSFGVV 377
Query 1091 LYELLT 1096
L E++T
Sbjct 378 LLEIIT 383
Score = 63.5 bits (153), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 57/257 (22%), Positives = 107/257 (42%), Gaps = 37/257 (14%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
+R ++ + ++D S ++ F + +M++ H +L + G G + +V Y+
Sbjct 207 NNRTVAVKKLAAMVDISTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYM 266
Query 691 EHGPLDVWLRRERGHVPMAWKM--VVAQQLASALSYLENKNLVHGNVCGRNILL------ 742
+G L L G P++W M +AQ A+ LSYL + +H ++ NILL
Sbjct 267 PNGSLLDRLSCLDGTPPLSWNMRCKIAQGAANGLSYLHENHHIHRDIKSANILLDEDFTA 326
Query 743 --ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800
+ GLA + F + + V ++APE L G ++ D + F
Sbjct 327 KISDFGLARASEKFAQ---------TVMTSRIVGTTAYMAPEALRG---EITPKSDIYSF 374
Query 801 GATLLEICFDGEAPLQSRSPS---------------EKEHFYQRQHRLPEPSCPQLATLT 845
G LLEI A + R P +++ ++ + + S + ++
Sbjct 375 GVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYVDRKMNDIDSTSIETMYSVA 434
Query 846 SQCLTYEPTQRPSFRTI 862
SQCL + +RP + +
Sbjct 435 SQCLHEKKNKRPDIKKV 451
>sp|Q14AX6|CDK12_MOUSE Cyclin-dependent kinase 12 OS=Mus musculus
OX=10090 GN=Cdk12 PE=1 SV=2
Length=1484
Score = 90.9 bits (224), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 67/215 (31%), Positives = 102/215 (47%), Gaps = 37/215 (17%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958
+GEG +G+V Y + TGE+VA+K ++ D + G+ +EI ILR L H+
Sbjct 729 IGEGTYGQV----YKAKDKDTGELVALKKVRLD---NEKEGFPITAIREIKILRQLVHQS 781
Query 959 IIKYKGCCEDQGEK--------SLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQI 1007
++ K D+ + + LV EY+ +G L L S + F +Q+
Sbjct 782 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSED--HIKSFMKQL 839
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED----GDS 1063
EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ Y E
Sbjct 840 MEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLAR-------LYNSEESRPYTNKV 892
Query 1064 PVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096
WY P L E ++ A DVWS G L EL T
Sbjct 893 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFT 927
Score = 35.8 bits (81), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 16/129 (12%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILL 742
+V EY++H D+ E G V + + + +QL L Y KN +H ++ NILL
Sbjct 807 LVFEYMDH---DLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILL 863
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKW 798
G IKL+D G+ S E R ++ W P L G + A+D W
Sbjct 864 NNSGQ-------IKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVW 916
Query 799 GFGATLLEI 807
G L E+
Sbjct 917 SCGCILGEL 925
>sp|Q9T020|Y4391_ARATH Probable receptor-like protein kinase At4g39110
OS=Arabidopsis thaliana OX=3702 GN=At4g39110 PE=3 SV=1
Length=878
Score = 90.5 bits (223), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 75/205 (37%), Positives = 101/205 (49%), Gaps = 28/205 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHEHI 959
+G G FG V + D DGT VAVK PQ G ++ EI +L L H H+
Sbjct 532 IGVGGFGNVYIGTLD---DGT--KVAVKR----GNPQSEQGITEFQTEIQMLSKLRHRHL 582
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ-QICEGMA----YL 1014
+ G C++ E + LV E++ G RD+L + LA L + +IC G A YL
Sbjct 583 VSLIGYCDENSE--MILVYEFMSNGPFRDHL--YGKNLAPLTWKQRLEICIGSARGLHYL 638
Query 1015 H---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-AP 1070
H AQ IHRD+ + N+LLD + K+ DFGL+K V G + G F Y P
Sbjct 639 HTGTAQGIIHRDVKSTNILLDEALVAKVADFGLSKDVAFGQNHVSTAVKGS---FGYLDP 695
Query 1071 ECLKEYKFYYASDVWSFGVTLYELL 1095
E + + SDV+SFGV L E L
Sbjct 696 EYFRRQQLTDKSDVYSFGVVLLEAL 720
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 69/297 (23%), Positives = 117/297 (39%), Gaps = 39/297 (13%)
Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651
LS L + T+ + V G G+ G +DD +V +K +P
Sbjct 516 LSELQEATKNFEASQIIGVGGFGNVYIGTLDDG------------TKVAVKRGNPQSEQG 563
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711
F ++S++ H HL + G C E I+V E++ +GP L + P+ WK
Sbjct 564 ITEFQTEIQMLSKLRHRHLVSLIGYCDENSEMILVYEFMSNGPFRDHLYG-KNLAPLTWK 622
Query 712 MVVAQQLASA--LSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ + SA L YL + ++H +V NILL L + F D G
Sbjct 623 QRLEICIGSARGLHYLHTGTAQGIIHRDVKSTNILLDE-ALVAKVADFGLSKDVAFGQNH 681
Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE-IC----FDGEAPLQSRSPS 821
+S + +L PE L+ D + FG LLE +C + + P + + +
Sbjct 682 VSTAVK-GSFGYLDPEYFR--RQQLTDKSDVYSFGVVLLEALCARPAINPQLPREQVNLA 738
Query 822 EKEHFYQRQ---HRLPEP---------SCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
E ++R+ ++ +P S + A +CL RP+ +L +L
Sbjct 739 EWAMQWKRKGLLEKIIDPHLAGTINPESMKKFAEAAEKCLEDYGVDRPTMGDVLWNL 795
>sp|Q61097|KSR1_MOUSE Kinase suppressor of Ras 1 OS=Mus musculus
OX=10090 GN=Ksr1 PE=1 SV=1
Length=873
Score = 90.1 bits (222), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 75/283 (27%), Positives = 132/283 (47%), Gaps = 38/283 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ-HRSGWKQEIDILRTLYHEHIIK 961
+G+G +G+V + GE VA++ L+ D Q H +K+E+ R HE+++
Sbjct 569 IGQGRWGRVHRGRWH------GE-VAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVL 621
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G C + L ++ + +L ++ P+ S+ + + AQ+I +GM YLHA+
Sbjct 622 FMGACMNPPH--LAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGI 679
Query 1020 IHRDLAARNVLLDNDRLV--KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY- 1076
+H+DL ++NV DN ++V G FG++ V E +++ D + + APE ++E
Sbjct 680 VHKDLKSKNVFYDNGKVVITDFGLFGISGVVREERRENQLKLSHDW-LCYLAPEIVREMI 738
Query 1077 --------KFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
F A+DV++FG YEL P + IG +G VL L
Sbjct 739 PGRDEDQLPFSKAADVYAFGTVWYELQARDWPFKHQPAEALIWQIGSGEGVRRVLASVSL 798
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ EV ++ CW + RP+F L+ +L+
Sbjct 799 GK-------------EVGEILSACWAFDLQERPSFSLLMDMLE 828
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 41/188 (22%), Positives = 79/188 (42%), Gaps = 24/188 (13%)
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
E+ + L +D + D F + Q H ++ G C+ P ++T + + L
Sbjct 585 EVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTL 644
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
++R + + + +AQ++ + YL K +VH ++ +N+ + +
Sbjct 645 HSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFY--------DNGKV 696
Query 756 KLSDPGV-GLGALSREERVER--------IPWLAPEC----LPGGANS---LSTAMDKWG 799
++D G+ G+ + REER E + +LAPE +PG S A D +
Sbjct 697 VITDFGLFGISGVVREERRENQLKLSHDWLCYLAPEIVREMIPGRDEDQLPFSKAADVYA 756
Query 800 FGATLLEI 807
FG E+
Sbjct 757 FGTVWYEL 764
>sp|Q15569|TESK1_HUMAN Dual specificity testis-specific protein
kinase 1 OS=Homo sapiens OX=9606 GN=TESK1 PE=1 SV=2
Length=626
Score = 89.7 bits (221), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 80/295 (27%), Positives = 126/295 (43%), Gaps = 50/295 (17%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G F +V Y + +G+++ +K K P +R +E+ ++ L H +I+++
Sbjct 63 IGAGFFSEV----YKVRHRQSGQVMVLKMNKL---PSNRGNTLREVQLMNRLRHPNILRF 115
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G C QG+ L + EY+ G+L L + L A I G+ YLH++ H
Sbjct 116 MGVCVHQGQ--LHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIARGLRYLHSKGVFH 173
Query 1022 RDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVFWYAPECLKEY 1076
RDL ++N L+ D +GDFGLA+ +P E R SP +W APE L+
Sbjct 174 RDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSP-YWMAPEVLRGE 232
Query 1077 KFYYASDVWSFGVTLYELLTH--CDSSQSPPTK--------FLELIGIAQGQMTVLRLTE 1126
+ +DV++FG+ L EL+ D P T+ F L+G
Sbjct 233 LYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVG------------- 279
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
D CP L +C E S R F + L+ + E+ AP
Sbjct 280 -----------DDCPLPFLLLAIHCCNLEPSTRAPFTEITQHLEWILEQLPEPAP 323
Score = 46.6 bits (109), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 81/319 (25%), Positives = 121/319 (38%), Gaps = 73/319 (23%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
R L + S RVD + +G G + VY+ R R SG KM+ +P
Sbjct 42 RALRSAVSSLARVDDFHCAE--KIGAGFFSEVYKVRHR--QSGQVMVLKMNK----LPS- 92
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+RG LR V LM+++ H ++ GVCV + +TEY+
Sbjct 93 NRGNTLREV-------------------QLMNRLRHPNILRFMGVCVHQGQLHALTEYMN 133
Query 692 HGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLAR----- 744
G L+ L P++W ++ +A +A L YL +K + H ++ +N L+ R
Sbjct 134 GGTLEQLLSSPE---PLSWPVRLHLALDIARGLRYLHSKGVFHRDLTSKNCLVRREDRGF 190
Query 745 ------LGLAEGTSPFIKLSDPGVGLGALSREERVERIP-WLAPECLPGGANSLSTAMDK 797
GLAE P GA V P W+APE L G D
Sbjct 191 TAVVGDFGLAEKI--------PVYREGARKEPLAVVGSPYWMAPEVLRG--ELYDEKADV 240
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---------HRLPEPSCP-QLATLTSQ 847
+ FG L E L +R P++ ++ + + L CP L
Sbjct 241 FAFGIVLCE--------LIARVPADPDYLPRTEDFGLDVPAFRTLVGDDCPLPFLLLAIH 292
Query 848 CLTYEPTQRPSFRTILRDL 866
C EP+ R F I + L
Sbjct 293 CCNLEPSTRAPFTEITQHL 311
>sp|Q9M8S2|LIPG2_ARATH Receptor-like kinase LIP2 OS=Arabidopsis
thaliana OX=3702 GN=LIP2 PE=1 SV=1
Length=558
Score = 89.4 bits (220), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 73/203 (36%), Positives = 104/203 (51%), Gaps = 16/203 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG+V Y T TG++VAVK L G ++ E+ L L H +++K
Sbjct 70 LGEGGFGRV----YKGTLKSTGQVVAVKQLDK-HGLHGNKEFQAEVLSLGQLDHPNLVKL 124
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHS---IGLAQLLLFAQQICEGMAYLHAQ 1017
G C D G++ L LV +Y+ GSL+D+L P+ + + A +G+ YLH +
Sbjct 125 IGYCAD-GDQRL-LVYDYISGGSLQDHLHEPKADSDPMDWTTRMQIAYAAAQGLDYLHDK 182
Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECL 1073
I+RDL A N+LLD+D K+ DFGL K P G + + + APE
Sbjct 183 ANPPVIYRDLKASNILLDDDFSPKLSDFGLHKLGPGTGDKMMALSSRVMGTYGYSAPEYT 242
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
+ SDV+SFGV L EL+T
Sbjct 243 RGGNLTLKSDVYSFGVVLLELIT 265
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 61/238 (26%), Positives = 103/238 (43%), Gaps = 37/238 (16%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV-PMAW--KMVVAQQL 718
+ Q+ H +L + G C G + ++V +Y+ G L L + PM W +M +A
Sbjct 113 LGQLDHPNLVKLIGYCADGDQRLLVYDYISGGSLQDHLHEPKADSDPMDWTTRMQIAYAA 172
Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD-------PGVGLGALSREE 771
A L YL +K + V R++ + + L + SP KLSD PG G ++
Sbjct 173 AQGLDYLHDK--ANPPVIYRDLKASNILLDDDFSP--KLSDFGLHKLGPGTGDKMMALSS 228
Query 772 RVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF---- 826
RV + APE GG +L+ D + FG LLE+ G L + P+++++
Sbjct 229 RVMGTYGYSAPEYTRGG--NLTLKSDVYSFGVVLLELIT-GRRALDTTRPNDEQNLVSWA 285
Query 827 ---YQRQHRLPEPSCP------------QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
++ R P+ + P Q + S C+ E + RP ++ L+ L
Sbjct 286 QPIFRDPKRYPDMADPVLENKFSERGLNQAVAIASMCVQEEASARPLISDVMVALSFL 343
>sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo
sapiens OX=9606 GN=PAK4 PE=1 SV=1
Length=591
Score = 89.4 bits (220), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 69/237 (29%), Positives = 111/237 (47%), Gaps = 21/237 (9%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
L V+P P S YL +GEG G V + T +G++VAVK K D
Sbjct 310 LVVDPGDPRS--------YLDNFIKIGEGSTGIVCIA----TVRSSGKLVAVK--KMDLR 355
Query 938 PQHRSGWK-QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996
Q R E+ I+R HE++++ E L +VME++ G+L D + +
Sbjct 356 KQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDE--LWVVMEFLEGGALTDIVTHTRMN 413
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
Q+ + + ++ LHAQ IHRD+ + ++LL +D VK+ DFG V E R
Sbjct 414 EEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQV--SKEVPR 471
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELI 1112
+ +P +W APE + + D+WS G+ + E++ PP K +++I
Sbjct 472 RKSLVGTP-YWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMI 527
>sp|Q9WTQ0|KPCT_RAT Protein kinase C theta type OS=Rattus norvegicus
OX=10116 GN=Prkcq PE=1 SV=2
Length=707
Score = 89.7 bits (221), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 68/209 (33%), Positives = 102/209 (49%), Gaps = 23/209 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI-LRTLYHEHIIK 961
LG+G FGKV L + T + A+KALK D ++ + +L EH
Sbjct 386 LGKGSFGKVFLAEFKRTK----QFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFL 441
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
C Q +++L VMEY+ G L ++ H L++ +A ++ G+ +LH++ +
Sbjct 442 THMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEVILGLQFLHSKGIV 501
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WYAPECLKE 1075
+RDL N+LLD D +KI DFG+ K G D + F + APE L
Sbjct 502 YRDLKLDNILLDRDGHIKIADFGMCKENMLG--------DAKTNTFCGTPDYIAPEILLG 553
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
K+ ++ D WSFGV LYE+L QSP
Sbjct 554 QKYNHSVDWWSFGVLLYEMLI----GQSP 578
>sp|A8WZ92|SPE8_CAEBR Spermatocyte protein spe-8 OS=Caenorhabditis
briggsae OX=6238 GN=spe-8 PE=2 SV=2
Length=479
Score = 89.0 bits (219), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 52/142 (37%), Positives = 82/142 (58%), Gaps = 10/142 (7%)
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLH 1015
++IK+ G C ++ + +VME+ SL D L + +L+ G+ YLH
Sbjct 244 NVIKFYGVC--TMKEPIMIVMEFCDGSSLEDVLLSKESKVSSEDKILYLFHAACGIDYLH 301
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLA-KAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+H IHRD+AARN LL++ +++KI DFGL+ K V + R+ G PV + APE LK
Sbjct 302 GKHVIHRDIAARNCLLNSKKVLKISDFGLSVKGVA-----IKERKGGCLPVKYMAPETLK 356
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ + ASD++S+G +YE+ T
Sbjct 357 KGFYSTASDIYSYGALVYEVYT 378
Score = 62.4 bits (150), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 50/198 (25%), Positives = 91/198 (46%), Gaps = 17/198 (9%)
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHG 733
+GVC ++V E+ + L+ L + V K++ A + YL K+++H
Sbjct 249 YGVCTMKEPIMIVMEFCDGSSLEDVLLSKESKVSSEDKILYLFHAACGIDYLHGKHVIHR 308
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER---IPWLAPECLPGGANS 790
++ RN LL + +K+SD G+ + ++ +ER + ++APE L G
Sbjct 309 DIAARNCLL-------NSKKVLKISDFGLSVKGVAIKERKGGCLPVKYMAPETLKKGF-- 359
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQS---RSPSEKEHFYQRQHRLP-EPSCPQLA-TLT 845
STA D + +GA + E+ DG+ P +S R ++ + L + CP+ +
Sbjct 360 YSTASDIYSYGALVYEVYTDGKTPFESCGLRGNELRKAIIGKSVILTIDVECPEFVKAIF 419
Query 846 SQCLTYEPTQRPSFRTIL 863
Q Y+ QR S + I+
Sbjct 420 EQSRLYDTEQRISSKRII 437
>sp|Q3MJK5|CDK12_RAT Cyclin-dependent kinase 12 OS=Rattus norvegicus
OX=10116 GN=Cdk12 PE=1 SV=1
Length=1484
Score = 90.5 bits (223), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 67/215 (31%), Positives = 102/215 (47%), Gaps = 37/215 (17%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958
+GEG +G+V Y + TGE+VA+K ++ D + G+ +EI ILR L H+
Sbjct 729 IGEGTYGQV----YKAKDKDTGELVALKKVRLD---NEKEGFPITAIREIKILRQLVHQS 781
Query 959 IIKYKGCCEDQGEK--------SLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQI 1007
++ K D+ + + LV EY+ +G L L S + F +Q+
Sbjct 782 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSED--HIKSFMKQL 839
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED----GDS 1063
EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ Y E
Sbjct 840 MEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLAR-------LYNSEESRPYTNKV 892
Query 1064 PVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096
WY P L E ++ A DVWS G L EL T
Sbjct 893 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFT 927
Score = 36.2 bits (82), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 16/129 (12%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILL 742
+V EY++H D+ E G V + + + +QL L Y KN +H ++ NILL
Sbjct 807 LVFEYMDH---DLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILL 863
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKW 798
G IKL+D G+ S E R ++ W P L G + A+D W
Sbjct 864 NNSGQ-------IKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVW 916
Query 799 GFGATLLEI 807
G L E+
Sbjct 917 SCGCILGEL 925
>sp|Q552C1|Y9957_DICDI Probable serine/threonine-protein kinase
DDB_G0276181 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0276181
PE=3 SV=1
Length=1555
Score = 90.5 bits (223), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 76/285 (27%), Positives = 125/285 (44%), Gaps = 47/285 (16%)
Query 913 LYCYDPTND--------GTGE--MVAVKALK--ADCGPQHRSGWKQEIDILRTLYHEHII 960
L +P+ND G+G +VAVK L AD P+ + E+ +L H +++
Sbjct 1034 LIARNPSNDIINKDAIIGSGPQIIVAVKKLHPLADPSPEMIQDFYNEVRVLSMFNHPNVV 1093
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
KY G C S+ VMEYVP G+L D L P I +L A I +G+ YLH+
Sbjct 1094 KYVGGCTKIANWSI--VMEYVPGGNLMDVLANPVLVIPYKLVLRMALDIAKGLHYLHSLG 1151
Query 1019 YIHRDLAARNVLLDNDRL-----VKIGDFG--LAKAVPEGHEYYRVREDGDS-------- 1063
+H D+ + N+L+ + +K+ DF + ++ + R GD+
Sbjct 1152 ILHLDMKSPNLLVSSLSTSAKVNIKVADFNTCINRSRITAGFFNRHTGSGDNNKVEKDSK 1211
Query 1064 --PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
W APE ++ + DV+SF + ++E++T + P + + Q+
Sbjct 1212 KGTTLWMAPEVIRGAMYSEKCDVYSFAIIMWEMVT-----RKLPYSHIAFNCEVEDQVL- 1265
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+G R P P C LM+ CW+ + RP F+ +I
Sbjct 1266 --------KGLRPPIPMHCNKNYTDLMEQCWDDDPENRPYFDTII 1302
Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 64/265 (24%), Positives = 107/265 (40%), Gaps = 30/265 (11%)
Query 634 GQELRVVLKVL----DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G ++ V +K L DPS I FY ++S +H ++ G C + +V EY
Sbjct 1053 GPQIIVAVKKLHPLADPSPEMIQ-DFYNEVRVLSMFNHPNVVKYVGGCTKIANWSIVMEY 1111
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
V G L L +P + +A +A L YL + ++H ++ N+L++ L +
Sbjct 1112 VPGGNLMDVLANPVLVIPYKLVLRMALDIAKGLHYLHSLGILHLDMKSPNLLVSSLSTSA 1171
Query 750 GTSPFIKLSDPG-------VGLGALSR------EERVER------IPWLAPECLPGGANS 790
+ IK++D + G +R +VE+ W+APE + G
Sbjct 1172 KVN--IKVADFNTCINRSRITAGFFNRHTGSGDNNKVEKDSKKGTTLWMAPEVIRGAM-- 1227
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQLAT-LTSQC 848
S D + F + E+ E E + R P P C + T L QC
Sbjct 1228 YSEKCDVYSFAIIMWEMVTRKLPYSHIAFNCEVEDQVLKGLRPPIPMHCNKNYTDLMEQC 1287
Query 849 LTYEPTQRPSFRTILRDLTRLQPHN 873
+P RP F TI+ ++++ N
Sbjct 1288 WDDDPENRPYFDTIIHSISKMIESN 1312
>sp|Q6CWQ4|IPL1_KLULA Spindle assembly checkpoint kinase OS=Kluyveromyces
lactis (strain ATCC 8585 / CBS 2359 / DSM 70799
/ NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=IPL1 PE=3 SV=1
Length=361
Score = 87.4 bits (215), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 57/197 (29%), Positives = 104/197 (53%), Gaps = 13/197 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960
LG+G FGKV YC + TG + A+KA++ Q+ + +++E++I + H+++
Sbjct 106 LGKGKFGKV--YCV--KHRETGLICALKAMEKKEIVQYTIQKQFRREVEIQGSFKHKNLT 161
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G D EK + L+MEYV G L +L + + F Q+ + Y+H+++
Sbjct 162 QLYGFFYD--EKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDYMHSKNI 219
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRD+ N+L+ + +K+ DFG + +G + R+ + + +PE +K ++
Sbjct 220 LHRDIKPENILIGFNNTIKLTDFGWSVYNEDGQK----RKTLCGTIDYLSPELIKSREYN 275
Query 1080 YASDVWSFGVTLYELLT 1096
DVW+ GV YELL
Sbjct 276 NKVDVWALGVLTYELLV 292
Score = 59.7 bits (143), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 53/216 (25%), Positives = 91/216 (42%), Gaps = 21/216 (10%)
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
+ I F + H +L ++G ++ EYV +G L +L+ G +
Sbjct 138 QYTIQKQFRREVEIQGSFKHKNLTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNN-GPLN 196
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--- 764
Q+A+AL Y+ +KN++H ++ NIL+ G + IKL+D G +
Sbjct 197 ETLASYFVYQMANALDYMHSKNILHRDIKPENILI-------GFNNTIKLTDFGWSVYNE 249
Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
R+ I +L+PE + + + +D W G E+ G P + + KE
Sbjct 250 DGQKRKTLCGTIDYLSPELIK--SREYNNKVDVWALGVLTYELLV-GSPPFEEDT---KE 303
Query 825 HFYQRQHR----LPEPSCPQLATLTSQCLTYEPTQR 856
Y+R R P PQ L + L +EP++R
Sbjct 304 MTYRRILRCDLKFPLNVSPQARDLIVRLLQFEPSKR 339
>sp|P10398|ARAF_HUMAN Serine/threonine-protein kinase A-Raf OS=Homo
sapiens OX=9606 GN=ARAF PE=1 SV=2
Length=606
Score = 89.4 bits (220), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 75/261 (29%), Positives = 118/261 (45%), Gaps = 42/261 (16%)
Query 927 VAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
VAVK LK + + +K E+ +LR H +I+ + G G ++ ++ S
Sbjct 333 VAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG---FAIITQWCEGSS 389
Query 986 LRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
L +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L VKIGDFG
Sbjct 390 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFG 449
Query 1044 LAKAVPEGHEYYRVREDGDSP-------VFWYAPECLKEYK---FYYASDVWSFGVTLYE 1093
LA + R G P V W A E ++ + + SDV+++GV LYE
Sbjct 450 LATV--------KTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYE 501
Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK----CPCEVYHLMK 1149
L+T S P IG ++ ++ RG P K CP + L+
Sbjct 502 LMT-----GSLPYSH---IGCRD------QIIFMVGRGYLSPDLSKISSNCPKAMRRLLS 547
Query 1150 NCWETEASFRPTFENLIPILK 1170
+C + + RP F ++ ++
Sbjct 548 DCLKFQREERPLFPQILATIE 568
Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 68/255 (27%), Positives = 106/255 (42%), Gaps = 24/255 (9%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
GR G VLKV P+ A AF ++ + H ++ G R P ++T++
Sbjct 327 GRWHGDVAVKVLKVSQPTAEQ-AQAFKNEMQVLRKTRHVNILLFMGFMTR-PGFAIITQW 384
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
E L L M + VA+Q A + YL KN++H ++ NI L E
Sbjct 385 CEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIF-----LHE 439
Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802
G + +K+ D G+ GA E+ + W+A E + N S D + +G
Sbjct 440 GLT--VKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 497
Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855
L E+ G P ++ F R + P+ S CP+ + L S CL ++ +
Sbjct 498 VLYEL-MTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREE 556
Query 856 RPSFRTILRDLTRLQ 870
RP F IL + LQ
Sbjct 557 RPLFPQILATIELLQ 571
>sp|O22833|LRK54_ARATH L-type lectin-domain containing receptor
kinase V.4 OS=Arabidopsis thaliana OX=3702 GN=LECRK54 PE=2
SV=1
Length=658
Score = 89.7 bits (221), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 64/200 (32%), Positives = 103/200 (52%), Gaps = 18/200 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+V + T G+ +AVK + D Q + EI + L H+++++
Sbjct 340 LGKGGFGQV----FKGTLPGSDAEIAVKRISHDS-KQGMQEFLAEISTIGRLRHQNLVRL 394
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH--- 1015
+G C + E L LV +++P GSL YL + + Q + I + YLH
Sbjct 395 QGYCRYKEE--LYLVYDFMPNGSLDKYLYHRANQEQLTWNQRFKIIKDIASALCYLHHEW 452
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074
Q IHRD+ NVL+D+ ++GDFGLAK +G++ R G FWY APE ++
Sbjct 453 VQVVIHRDIKPANVLIDHQMNARLGDFGLAKLYDQGYDPQTSRVAG---TFWYIAPELIR 509
Query 1075 EYKFYYASDVWSFGVTLYEL 1094
+ +DV++FG+ + E+
Sbjct 510 SGRATTGTDVYAFGLFMLEV 529
Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 45/197 (23%), Positives = 87/197 (44%), Gaps = 14/197 (7%)
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
G + + +K + F S + ++ H +L + G C E +V +++ +G
Sbjct 355 GSDAEIAVKRISHDSKQGMQEFLAEISTIGRLRHQNLVRLQGYCRYKEELYLVYDFMPNG 414
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLA-RLGL 747
LD +L + W + + + +ASAL YL + + ++H ++ N+L+ ++
Sbjct 415 SLDKYLYHRANQEQLTWNQRFKIIKDIASALCYLHHEWVQVVIHRDIKPANVLIDHQMNA 474
Query 748 AEGTSPFIKLSDPGVGLGALSREERVERIPW-LAPECLPGGANSLSTAMDKWGFGATLLE 806
G KL D G + RV W +APE + G +T D + FG +LE
Sbjct 475 RLGDFGLAKLYDQGYD----PQTSRVAGTFWYIAPELIRSG--RATTGTDVYAFGLFMLE 528
Query 807 ICFDGEAPLQSRSPSEK 823
+ G ++ R+ S++
Sbjct 529 VSC-GRRLIERRTASDE 544
>sp|Q9R012|PLK2_RAT Serine/threonine-protein kinase PLK2 OS=Rattus
norvegicus OX=10116 GN=Plk2 PE=1 SV=1
Length=682
Score = 89.7 bits (221), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 76/283 (27%), Positives = 130/283 (46%), Gaps = 32/283 (11%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWK 945
DPT KRY + + LG+G F K CY+ T+ ++ A K + P R
Sbjct 72 DPTT-GKRYCRG-KVLGKGGFAK----CYEMTDLTNNKVYAAKIIPHSRVAKPHQREKID 125
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFA 1004
+EI++ R L+H+H++++ ED+ +++ +++EY S+ L R + ++ +
Sbjct 126 KEIELHRILHHKHVVQFYHYFEDK--ENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 183
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDS 1063
+QI G+ YLH Q +HRDL N ++ +K+GDFGLA + P H R R +
Sbjct 184 RQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEH---RRRTICGT 240
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
P + +PE L + SD+W+ G +Y + L+G + T L+
Sbjct 241 PNYL-SPEVLNKQGHGCESDIWALGCVMYTM----------------LLGRPPFETTNLK 283
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
T R R P HL+ + RP+ +++I
Sbjct 284 ETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDII 326
>sp|B5X564|CDC2C_ARATH Cyclin-dependent kinase C-2 C OS=Arabidopsis
thaliana OX=3702 GN=CDC2C PE=1 SV=1
Length=644
Score = 89.4 bits (220), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 67/205 (33%), Positives = 100/205 (49%), Gaps = 15/205 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLY 955
+K+ +G+G + V + TG+MVA+K +K D P+ +EI ILR L
Sbjct 105 FQKLEKIGQGTYSSV----FRAREVETGKMVALKKVKFDNLQPESIRFMAREILILRKLN 160
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013
H +I+K +G + S+ LV EY+ L L P Q+ + +Q+ G+ +
Sbjct 161 HPNIMKLEGIVTSRASSSIYLVFEYMEHDLAGLSSN-PDIRFTEPQIKCYMKQLLWGLEH 219
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWY-APE 1071
H + IHRD+ A N+L++N ++K+GDFGLA V P R WY APE
Sbjct 220 CHMRGVIHRDIKASNILVNNKGVLKLGDFGLANVVTPSNKNQLTSR----VVTLWYRAPE 275
Query 1072 CLKEYKFYYAS-DVWSFGVTLYELL 1095
L Y S D+WS G E+L
Sbjct 276 LLMGSTSYGVSVDLWSVGCVFAEIL 300
>sp|Q9FFW5|PERK8_ARATH Proline-rich receptor-like protein kinase
PERK8 OS=Arabidopsis thaliana OX=3702 GN=PERK8 PE=1 SV=1
Length=681
Score = 89.4 bits (220), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 91/292 (31%), Positives = 131/292 (45%), Gaps = 37/292 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG C G VAVK LK G Q +K E++I+ ++H H++
Sbjct 345 LGEGGFG-----CVYKGVLSDGREVAVKQLKI-GGSQGEREFKAEVEIISRVHHRHLVTL 398
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017
G C E+ LV +YVP +L +L H+ G + + A G+AYLH
Sbjct 399 VGYC--ISEQHRLLVYDYVPNNTLHYHL--HAPGRPVMTWETRVRVAAGAARGIAYLHED 454
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRD+ + N+LLDN + DFGLAK E V + APE
Sbjct 455 CHPRIIHRDIKSSNILLDNSFEALVADFGLAKIAQELDLNTHVSTRVMGTFGYMAPEYAT 514
Query 1075 EYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQ---GQ-MTVLRLTEL 1127
K +DV+S+GV L EL+T D+SQ P L+ A+ GQ + EL
Sbjct 515 SGKLSEKADVYSYGVILLELITGRKPVDTSQ--PLGDESLVEWARPLLGQAIENEEFDEL 572
Query 1128 LERGERLPRPDK--CPCEVYHLMK---NCWETEASFRPTFENLIPILKTVHE 1174
++ PR K P E++ +++ C A+ RP ++ L T+ E
Sbjct 573 VD-----PRLGKNFIPGEMFRMVEAAAACVRHSAAKRPKMSQVVRALDTLEE 619
Score = 43.1 bits (100), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 58/251 (23%), Positives = 97/251 (39%), Gaps = 47/251 (19%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F ++S+V H HL + G C+ ++V +YV + L L G M W ++
Sbjct 380 FKAEVEIISRVHHRHLVTLVGYCISEQHRLLVYDYVPNNTLHYHLHAP-GRPVMTWETRV 438
Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPG 761
VA A ++YL ++H ++ NILL A GLA K++
Sbjct 439 RVAAGAARGIAYLHEDCHPRIIHRDIKSSNILLDNSFEALVADFGLA-------KIAQE- 490
Query 762 VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP- 820
+ L + ++APE G LS D + +G LLE+ G P+ + P
Sbjct 491 LDLNTHVSTRVMGTFGYMAPEYATSG--KLSEKADVYSYGVILLEL-ITGRKPVDTSQPL 547
Query 821 ----------------SEKEHFYQ-RQHRLPEPSCP----QLATLTSQCLTYEPTQRPSF 859
E E F + RL + P ++ + C+ + +RP
Sbjct 548 GDESLVEWARPLLGQAIENEEFDELVDPRLGKNFIPGEMFRMVEAAAACVRHSAAKRPKM 607
Query 860 RTILRDLTRLQ 870
++R L L+
Sbjct 608 SQVVRALDTLE 618
>sp|P53351|PLK2_MOUSE Serine/threonine-protein kinase PLK2 OS=Mus
musculus OX=10090 GN=Plk2 PE=1 SV=1
Length=682
Score = 89.4 bits (220), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 76/283 (27%), Positives = 130/283 (46%), Gaps = 32/283 (11%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWK 945
DPT KRY + + LG+G F K CY+ T+ ++ A K + P R
Sbjct 72 DPTT-GKRYCRG-KVLGKGGFAK----CYEMTDLTNNKVYAAKIIPHSRVAKPHQREKID 125
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFA 1004
+EI++ R L+H+H++++ ED+ +++ +++EY S+ L R + ++ +
Sbjct 126 KEIELHRLLHHKHVVQFYHYFEDK--ENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 183
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDS 1063
+QI G+ YLH Q +HRDL N ++ +K+GDFGLA + P H R R +
Sbjct 184 RQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEH---RRRTICGT 240
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
P + +PE L + SD+W+ G +Y + L+G + T L+
Sbjct 241 PNYL-SPEVLNKQGHGCESDIWALGCVMYTM----------------LLGRPPFETTNLK 283
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
T R R P HL+ + RP+ +++I
Sbjct 284 ETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDII 326
>sp|Q2TA25|PLK1_BOVIN Serine/threonine-protein kinase PLK1 OS=Bos
taurus OX=9913 GN=PLK1 PE=2 SV=2
Length=602
Score = 89.4 bits (220), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 76/267 (28%), Positives = 117/267 (44%), Gaps = 28/267 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960
LG+G F K C++ ++ T E+ A K + P + EI I R+L H+H++
Sbjct 57 LGKGGFAK----CFEISDADTKEVFAGKIVPKSLLLKPHQKEKMSMEISIHRSLAHQHVV 112
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G ED + +V+E SL + + R ++ + + +QI G YLH
Sbjct 113 GFHGFFEDND--FVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHGNRV 170
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRDL N+ L+ D VKIGDFGLA V E R + +P + APE L +
Sbjct 171 IHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGE--RKKTLCGTPN-YIAPEVLSKKGHS 227
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+ DVWS G +Y L L+G + + L+ T L + P
Sbjct 228 FEVDVWSIGCIMYTL----------------LVGKPPFETSCLKETYLRIKNNEYSIPKH 271
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLI 1166
L+K + + + RPT L+
Sbjct 272 INPVASSLIKKMLQPDPTARPTIHELL 298
Score = 40.8 bits (94), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 45/211 (21%), Positives = 83/211 (39%), Gaps = 16/211 (8%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+ ++H H+ HG +V E L + L + R + +Q+
Sbjct 101 SIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSL-LELHKRRKALTEPEARYYLRQIV 159
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776
YL ++H R++ L L L E +K+ D G+ ER + +
Sbjct 160 LGCQYLHGNRVIH-----RDLKLGNLFLNEDLE--VKIGDFGLATKVEYDGERKKTLCGT 212
Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLP 834
++APE L +S +D W G + + G+ P ++ E ++ +P
Sbjct 213 PNYIAPEVLSKKGHSFE--VDVWSIGCIMYTLLV-GKPPFETSCLKETYLRIKNNEYSIP 269
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ P ++L + L +PT RP+ +L D
Sbjct 270 KHINPVASSLIKKMLQPDPTARPTIHELLND 300
>sp|Q9HGY5|PHO85_CANAX Negative regulator of the PHO system OS=Candida
albicans OX=5476 GN=PHO85 PE=3 SV=1
Length=326
Score = 86.3 bits (212), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 62/206 (30%), Positives = 99/206 (48%), Gaps = 17/206 (8%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+++ LGEG + V Y N TG +VA+K + D S +EI +++ L H
Sbjct 8 FQQLEKLGEGTYATV----YKGRNRATGALVALKEISLDSEEGTPSTAIREISLMKELDH 63
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----SIGLAQLLLFAQQICEGMA 1012
E+I+ E L LV EY+ L+ Y+ H ++ L + F Q+ +G+
Sbjct 64 ENIVTLYDVI--HTENKLTLVFEYMD-KDLKKYMEVHGQQSALDLKVVKSFMFQLLKGIM 120
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APE 1071
+ H +HRDL +N+L++N +K+GDFGLA+A + + WY AP+
Sbjct 121 FCHDNRVLHRDLKPQNLLINNKGELKLGDFGLARAFGIPFNTF----SNEVVTLWYRAPD 176
Query 1072 CLKEYKFYYAS-DVWSFGVTLYELLT 1096
L + Y S D+WS G E+ T
Sbjct 177 VLLGSRAYTTSIDIWSAGCIFAEMCT 202
Score = 41.2 bits (95), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 51/227 (22%), Positives = 96/227 (42%), Gaps = 38/227 (17%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ QL LG+GT VY+GR R G+ LV ++ LD
Sbjct 7 QFQQLEKLGEGTYATVYKGRNRATGA-------------LVALKEIS---------LDSE 44
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
+ A E SLM ++ H ++ ++ V + +V EY++ L ++
Sbjct 45 EGTPSTAIREI-SLMKELDHENIVTLYDVIHTENKLTLVFEYMDKD-LKKYMEVHGQQSA 102
Query 708 MAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV--- 762
+ K+V + QL + + + ++H ++ +N+L+ G +KL D G+
Sbjct 103 LDLKVVKSFMFQLLKGIMFCHDNRVLHRDLKPQNLLINNKGE-------LKLGDFGLARA 155
Query 763 -GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
G+ + V + + AP+ L G + + +T++D W G E+C
Sbjct 156 FGIPFNTFSNEVVTLWYRAPDVLLG-SRAYTTSIDIWSAGCIFAEMC 201
>sp|Q9NYV4|CDK12_HUMAN Cyclin-dependent kinase 12 OS=Homo sapiens
OX=9606 GN=CDK12 PE=1 SV=2
Length=1490
Score = 90.1 bits (222), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 67/215 (31%), Positives = 101/215 (47%), Gaps = 37/215 (17%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958
+GEG +G+V Y + TGE+VA+K ++ D + G+ +EI ILR L H
Sbjct 733 IGEGTYGQV----YKAKDKDTGELVALKKVRLD---NEKEGFPITAIREIKILRQLIHRS 785
Query 959 IIKYKGCCEDQGEK--------SLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQI 1007
++ K D+ + + LV EY+ +G L L S + F +Q+
Sbjct 786 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSED--HIKSFMKQL 843
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED----GDS 1063
EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ Y E
Sbjct 844 MEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLAR-------LYNSEESRPYTNKV 896
Query 1064 PVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096
WY P L E ++ A DVWS G L EL T
Sbjct 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFT 931
Score = 35.8 bits (81), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 16/129 (12%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILL 742
+V EY++H D+ E G V + + + +QL L Y KN +H ++ NILL
Sbjct 811 LVFEYMDH---DLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILL 867
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKW 798
G IKL+D G+ S E R ++ W P L G + A+D W
Sbjct 868 NNSGQ-------IKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVW 920
Query 799 GFGATLLEI 807
G L E+
Sbjct 921 SCGCILGEL 929
>sp|Q5R4L1|PLK2_PONAB Serine/threonine-protein kinase PLK2 OS=Pongo
abelii OX=9601 GN=PLK2 PE=3 SV=1
Length=685
Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 76/283 (27%), Positives = 130/283 (46%), Gaps = 32/283 (11%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWK 945
DPT KRY + + LG+G F K CY+ T+ ++ A K + P R
Sbjct 75 DPTT-GKRYCRG-KVLGKGGFAK----CYEMTDLTNNKVYAAKIIPHSRVAKPHQREKID 128
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFA 1004
+EI++ R L+H+H++++ ED+ +++ +++EY S+ L R + ++ +
Sbjct 129 KEIELHRILHHKHVVQFYHYFEDK--ENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 186
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDS 1063
+QI G+ YLH Q +HRDL N ++ +K+GDFGLA + P H R R +
Sbjct 187 RQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEH---RRRTICGT 243
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
P + +PE L + SD+W+ G +Y + L+G + T L+
Sbjct 244 PNYL-SPEVLNKQGHGCESDIWALGCVMYTM----------------LLGRPPFETTNLK 286
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
T R R P HL+ + RP+ +++I
Sbjct 287 ETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDII 329
>sp|Q8RWC9|CIPK1_ARATH CBL-interacting serine/threonine-protein
kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CIPK1 PE=1 SV=2
Length=444
Score = 87.8 bits (216), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 74/208 (36%), Positives = 106/208 (51%), Gaps = 23/208 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRS-GWKQEIDILRTLYHEH 958
R LGEG+FGKV + D +G AVK + K+ + S K+EI L+ L H H
Sbjct 24 RTLGEGNFGKVK-FAKDTV---SGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLKHPH 79
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQ 1017
I++ + + + +VME V G L D + + + QQ+ +G++Y H++
Sbjct 80 IVRLHEVLASKTK--INMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSK 137
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG------DSPVFWYAPE 1071
HRDL NVLLD +KI DFGL+ A+P+ R+DG SP + APE
Sbjct 138 GVFHRDLKLENVLLDAKGHIKITDFGLS-ALPQ-----HFRDDGLLHTTCGSP-NYVAPE 190
Query 1072 CLKEYKFY-YASDVWSFGVTLYELLTHC 1098
L + ASD+WS GV LY +LT C
Sbjct 191 VLANRGYDGAASDIWSCGVILYVILTGC 218
Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 56/232 (24%), Positives = 90/232 (39%), Gaps = 32/232 (14%)
Query 641 LKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-D 696
+K++D S + +L + + H H+ +H V + MV E V G L D
Sbjct 48 VKIIDKSRIADLNFSLQIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFD 107
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+ + KM QQL +SY +K + H ++ N+LL G IK
Sbjct 108 RIVSNGKLTETDGRKMF--QQLIDGISYCHSKGVFHRDLKLENVLLDAKG-------HIK 158
Query 757 LSDPGVGLGALSREERVERI--------PWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
++D GL AL + R + + ++APE L A D W G +L +
Sbjct 159 ITD--FGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRGYD-GAASDIWSCGV-ILYVI 214
Query 809 FDGEAPLQSRSPSEKEHFYQRQHR----LPEPSCPQLATLTSQCLTYEPTQR 856
G P R+ + YQ+ + +P P T+ + L P R
Sbjct 215 LTGCLPFDDRNLAV---LYQKICKGDPPIPRWLSPGARTMIKRMLDPNPVTR 263
>sp|Q9Z1J2|NEK4_MOUSE Serine/threonine-protein kinase Nek4 OS=Mus
musculus OX=10090 GN=Nek4 PE=1 SV=1
Length=792
Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 61/200 (31%), Positives = 101/200 (51%), Gaps = 10/200 (5%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+R +G G +G+V+L + DG ++ L+ + + R +QE +L L H +I
Sbjct 9 MRVVGRGSYGEVTLVKH--RRDGKQYVIKKLNLR-NASSRERRAAEQEAQLLSQLKHPNI 65
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLHA 1016
+ YK E G+ L +VM + G L L L +Q++ + QI + YLH
Sbjct 66 VTYKESWEG-GDGLLYIVMGFCEGGDLYRKLKEQKGQLLPESQVVEWFVQIAMALQYLHE 124
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+H +HRDL +NV L ++K+GD G+A+ + E H G +P ++ +PE
Sbjct 125 KHILHRDLKTQNVFLTRTNIIKVGDLGIARVL-ENHGDMASTLIG-TP-YYMSPELFSNK 181
Query 1077 KFYYASDVWSFGVTLYELLT 1096
+ Y SDVW+ G +YE+ T
Sbjct 182 PYNYKSDVWALGCCVYEMAT 201
Score = 42.0 bits (97), Expect = 0.042, Method: Compositional matrix adjust.
Identities = 50/219 (23%), Positives = 95/219 (43%), Gaps = 18/219 (8%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEYVEHGPLDVWLRRERGHV-PMAW 710
A + A L+SQ+ H ++ + G + ++ V + E G L L+ ++G + P +
Sbjct 49 AAEQEAQLLSQLKHPNI-VTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPESQ 107
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ Q+A AL YL K+++H ++ +N+ L R + IK+ D G+ +
Sbjct 108 VVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNI-------IKVGDLGIARVLENHG 160
Query 771 ERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ + +++PE + + D W G + E+ A S
Sbjct 161 DMASTLIGTPYYMSPELFSNKPYNYKS--DVWALGCCVYEMATLKHAFNAKDMNSLVYRI 218
Query 827 YQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ + +P+ +LA L L+ P +RPS R+ILR
Sbjct 219 IEGKLPPMPKVYSTELAELIRTMLSRRPEERPSVRSILR 257
>sp|Q5QNM6|CIPKD_ORYSJ Putative CBL-interacting protein kinase
13 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK13 PE=3
SV=1
Length=511
Score = 88.6 bits (218), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 68/204 (33%), Positives = 104/204 (51%), Gaps = 24/204 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYHEH 958
LG+G+F KV Y N TGE VA+K ++ + +SG K+EI +LR + H H
Sbjct 31 LGQGNFAKV----YHARNVATGEEVAIKVMEKE--KIFKSGLTAHIKREIAVLRRVRHPH 84
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I++ + + VMEYV G L + R + A + QQ+ +A+ HA+
Sbjct 85 IVQLYEVMATK--LRIYFVMEYVRGGELFARVARGRLPEADARRYFQQLVSAVAFCHARG 142
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WYAPECL 1073
HRD+ N+L+D+ +K+ DFGL+ AV +G +R DG F + APE L
Sbjct 143 VFHRDIKPENLLVDDAGDLKVSDFGLS-AVADG-----MRRDGLFHTFCGTPAYVAPEVL 196
Query 1074 KEYKFYYA-SDVWSFGVTLYELLT 1096
+ A +D+WS GV L+ L+
Sbjct 197 SRRGYDAAGADLWSCGVVLFVLMA 220
Score = 50.8 bits (120), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 55/218 (25%), Positives = 93/218 (43%), Gaps = 28/218 (13%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
+++ +V H H+ ++ V V EYV G L + R RG +P A QQL
Sbjct 75 AVLRRVRHPHIVQLYEVMATKLRIYFVMEYVRGGEL--FARVARGRLPEADARRYFQQLV 132
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776
SA+++ + + H ++ N+L+ G +K+SD GL A++ R + +
Sbjct 133 SAVAFCHARGVFHRDIKPENLLVDDAGD-------LKVSD--FGLSAVADGMRRDGLFHT 183
Query 777 -----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
++APE L + A D W G L + G P Q R+ + Y++ H
Sbjct 184 FCGTPAYVAPEVLSRRGYDAAGA-DLWSCGVVLF-VLMAGYLPFQDRNLA---GMYRKIH 238
Query 832 ----RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
R P+ P+L L L P +R + I+ +
Sbjct 239 KGDFRCPKWFSPELIRLLRGVLVTNPQRRATAEGIMEN 276
>sp|Q9M0X5|CRK25_ARATH Cysteine-rich receptor-like protein kinase
25 OS=Arabidopsis thaliana OX=3702 GN=CRK25 PE=3 SV=1
Length=675
Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 85/283 (30%), Positives = 128/283 (45%), Gaps = 29/283 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG+V TGE VA+K L + Q +K E+D++ L H ++ K
Sbjct 353 LGHGGFGEVY-----KGQLITGETVAIKRL-SQGSTQGAEEFKNEVDVVAKLQHRNLAKL 406
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
G C D EK LV E+VP SL +L R + + + I G+ YLH
Sbjct 407 LGYCLDGEEK--ILVYEFVPNKSLDYFLFDNEKRRVLDWQRRYKIIEGIARGILYLHRDS 464
Query 1019 ---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074
IHRDL A N+LLD D KI DFG+A+ G + + + Y +PE
Sbjct 465 RLTIIHRDLKASNILLDADMHPKISDFGMARIF--GVDQTQANTKRIVGTYGYMSPEYAI 522
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL------TELL 1128
K+ SDV+SFGV + EL+T +S F E G+ V +L EL+
Sbjct 523 HGKYSVKSDVYSFGVLVLELITGKKNSS-----FYEEDGLGDLVTYVWKLWVENSPLELV 577
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ R H+ C + ++S RP+ ++++ ++ +
Sbjct 578 DEAMRGNFQTNEVIRCIHIALLCVQEDSSERPSMDDILVMMNS 620
Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 70/304 (23%), Positives = 121/304 (40%), Gaps = 50/304 (16%)
Query 517 EGWGRSFPS-VRELGAALQGCLLRAGDDCFSL-RRCCLPQPGETSNLIIMRGARASPRTL 574
+G G++ V + + C+L G C+ L RR ET +L S TL
Sbjct 276 KGKGKNLTVIVTAIAVPVSVCVLLLGAMCWLLARRRNNKLSAETEDL--DEDGITSTETL 333
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
Q S + ++ + LG G VY+G+L + G
Sbjct 334 QF-QFSAIEAATNKFSESNKLGHGGFGEVYKGQL-------------------ITGE--- 370
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
V +K L A F +++++ H +LA + G C+ G E I+V E+V +
Sbjct 371 ---TVAIKRLSQGSTQGAEEFKNEVDVVAKLQHRNLAKLLGYCLDGEEKILVYEFVPNKS 427
Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAE 749
LD +L + W + + + +A + YL + ++H ++ NILL
Sbjct 428 LDYFLFDNEKRRVLDWQRRYKIIEGIARGILYLHRDSRLTIIHRDLKASNILL------- 480
Query 750 GTSPFIKLSDPGVG--LGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGAT 803
K+SD G+ G + +RI +++PE G S+ + D + FG
Sbjct 481 DADMHPKISDFGMARIFGVDQTQANTKRIVGTYGYMSPEYAIHGKYSVKS--DVYSFGVL 538
Query 804 LLEI 807
+LE+
Sbjct 539 VLEL 542
>sp|Q86AE1|Y9853_DICDI Probable serine/threonine-protein kinase
DDB_G0271538 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0271538
PE=3 SV=1
Length=527
Score = 88.6 bits (218), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 82/290 (28%), Positives = 129/290 (44%), Gaps = 34/290 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--DCGPQHRSGWKQEIDILRTLYHEHI 959
++G G FG+V Y G VAVK L P + +EI IL+ + H +I
Sbjct 38 EIGRGSFGQVQKASY------FGTDVAVKQLSTLVSIDPDYFKFMLREIKILKGMRHPNI 91
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL---FAQQICEGMAYLHA 1016
++Y G C +G +V EY+ G L ++ + L A I +YLH+
Sbjct 92 VQYIGACCHEGR--YMIVTEYIKGGDLHQFIKARGVSNISWTLRMKLALDIASAFSYLHS 149
Query 1017 QHYIHRDLAARNVLLDN--DRL--VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+ I RDL A+N+L+D D L K+ DFG A+ + +G + + G +PE
Sbjct 150 KKVIFRDLKAKNILVDEIGDGLYRAKVIDFGFAR-IFDGKDTNNLTICGSENTM--SPEV 206
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL-LERG 1131
+ + + DV+S+GV L EL+ C S + Q + T + ++ LE+
Sbjct 207 IVGSSYNDSCDVYSYGVLLLELI--CGSR----------VVKTQLKRTPMNAFDMNLEKA 254
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
E L P+ CP L K C RPTF+ ++ LK + + P
Sbjct 255 EHLA-PESCPRAFMDLAKWCCSYNPKDRPTFKIVVEGLKVLTNQQLKDLP 303
Score = 73.9 bits (180), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 67/268 (25%), Positives = 118/268 (44%), Gaps = 15/268 (6%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G D + L +DP + L ++ + H ++ G C ++VTEY
Sbjct 54 GTDVAVKQLSTLVSIDPDYFKFML---REIKILKGMRHPNIVQYIGACCHEGRYMIVTEY 110
Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
++ G L +++ RG ++W +M +A +ASA SYL +K ++ ++ +NIL+ +G
Sbjct 111 IKGGDLHQFIK-ARGVSNISWTLRMKLALDIASAFSYLHSKKVIFRDLKAKNILVDEIGD 169
Query 748 AEGTSPFIKLSDPGVGLGALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+ I + G + + ++PE + G +S + + D + +G LLE
Sbjct 170 GLYRAKVIDFGFARIFDGKDTNNLTICGSENTMSPEVIVG--SSYNDSCDVYSYGVLLLE 227
Query 807 -ICFDGEAPLQ-SRSPSE--KEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRT 861
IC Q R+P + + +H PE SCP+ L C +Y P RP+F+
Sbjct 228 LICGSRVVKTQLKRTPMNAFDMNLEKAEHLAPE-SCPRAFMDLAKWCCSYNPKDRPTFKI 286
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDP 889
++ L L L D+ P DP
Sbjct 287 VVEGLKVLTNQQLKDLPVKGKSKPYIDP 314
>sp|Q54L00|LIMKA_DICDI Probable LIM domain-containing serine/threonine-protein
kinase DDB_G0287001 OS=Dictyostelium discoideum
OX=44689 GN=DDB_G0287001 PE=3 SV=1
Length=650
Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 72/255 (28%), Positives = 115/255 (45%), Gaps = 24/255 (9%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH--IIKYKGCCEDQGEKSLQLVMEYV 981
G VA+K ++ + + +E+ I+ + +H ++ G Q +K L V E V
Sbjct 407 GRDVAIKVYSSENFCFNIEEFDREVTIMSLIDSDHPNFTRFYGA-NKQNKKYLFHVSELV 465
Query 982 PLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
GSLRD L LA L A I M +LH+ IHRDL + NVL+ D K+
Sbjct 466 KSGSLRDLLLDKEKPLAYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKV 525
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFG ++ V + G S + +PE K + DV++FG+ L+E++
Sbjct 526 IDFGTSRNVDLAKQM--TLNLGTS--CYMSPELFKGNGYDETCDVYAFGIVLWEII---- 577
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
++ P + + + L+ +GER P CP E L+K CW + R
Sbjct 578 -ARKEPYE----------NINSWSIPVLVAKGERPTIPADCPSEYSKLIKACWTDKPKKR 626
Query 1160 PTFENLIPILKTVHE 1174
P+F+ + LK + E
Sbjct 627 PSFKEICDTLKKISE 641
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 56/228 (25%), Positives = 104/228 (46%), Gaps = 28/228 (12%)
Query 655 FYETASLMSQVSHTHLAFV--HGVCVRGPENIM-VTEYVEHGPL-DVWLRRERGHVPMAW 710
F ++MS + H F +G + + + V+E V+ G L D+ L +E+ P+A+
Sbjct 427 FDREVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSELVKSGSLRDLLLDKEK---PLAY 483
Query 711 --KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDP-GVG 763
++ +A +A+A+ +L + ++H ++ N+L+ A+ GTS + L+ +
Sbjct 484 FTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLAKQMTLN 543
Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
LG +++PE G N D + FG L EI E P ++ +
Sbjct 544 LGTSC---------YMSPELFKG--NGYDETCDVYAFGIVLWEIIARKE-PYENINSWSI 591
Query 824 EHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ R P+ CP + + L C T +P +RPSF+ I L ++
Sbjct 592 PVLVAKGERPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTLKKI 639
>sp|Q9NYY3|PLK2_HUMAN Serine/threonine-protein kinase PLK2 OS=Homo
sapiens OX=9606 GN=PLK2 PE=1 SV=3
Length=685
Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 76/283 (27%), Positives = 130/283 (46%), Gaps = 32/283 (11%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWK 945
DPT KRY + + LG+G F K CY+ T+ ++ A K + P R
Sbjct 75 DPTT-GKRYCRG-KVLGKGGFAK----CYEMTDLTNNKVYAAKIIPHSRVAKPHQREKID 128
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFA 1004
+EI++ R L+H+H++++ ED+ +++ +++EY S+ L R + ++ +
Sbjct 129 KEIELHRILHHKHVVQFYHYFEDK--ENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 186
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDS 1063
+QI G+ YLH Q +HRDL N ++ +K+GDFGLA + P H R R +
Sbjct 187 RQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEH---RRRTICGT 243
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
P + +PE L + SD+W+ G +Y + L+G + T L+
Sbjct 244 PNYL-SPEVLNKQGHGCESDIWALGCVMYTM----------------LLGRPPFETTNLK 286
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
T R R P HL+ + RP+ +++I
Sbjct 287 ETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDII 329
>sp|Q86HN7|PLK_DICDI Probable serine/threonine-protein kinase
PLK OS=Dictyostelium discoideum OX=44689 GN=PLK PE=3 SV=1
Length=978
Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 65/197 (33%), Positives = 100/197 (51%), Gaps = 15/197 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960
LG+G F K CY T T + A K + + RS K EI I +L HE+I+
Sbjct 169 LGKGGFAK----CYLMTEVETNRIYAAKIIPKSTLQKTRARSKLKSEIKIHSSLSHENIV 224
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
K++ C E+ E+++ +++E ++ D + R + + + Q+ + YLH +
Sbjct 225 KFEHCFEN--EENVYILLELCNQKTVMDIHKKRKYLMEYETKYYVYQVIMAVQYLHNNNI 282
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRDL N+ +DN R +K+GDFGL+ V G R + +P + APE L +
Sbjct 283 IHRDLKLGNLFIDNMR-IKLGDFGLSTKVEHGE---RKKTICGTPNYI-APEILDNSNGH 337
Query 1080 -YASDVWSFGVTLYELL 1095
Y DVWS G+ LY LL
Sbjct 338 SYEVDVWSIGIILYTLL 354
Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 53/214 (25%), Positives = 95/214 (44%), Gaps = 27/214 (13%)
Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
+ S +SH ++ F H C EN+ + + + + + ++R ++ Q+
Sbjct 214 IHSSLSHENIVKFEH--CFENEENVYILLELCNQKTVMDIHKKRKYLMEYETKYYVYQVI 271
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776
A+ YL N N++H ++ N+ + + IKL D G+ + ER + I
Sbjct 272 MAVQYLHNNNIIHRDLKLGNLFIDNMR--------IKLGDFGLS-TKVEHGERKKTICGT 322
Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR--QHRL 833
++APE L +N S +D W G L + G+ P ++ S+ +H YQR Q++
Sbjct 323 PNYIAPEIL-DNSNGHSYEVDVWSIGIILYTLLI-GKPPFET---SDVKHTYQRIKQNQY 377
Query 834 PEPSCPQLA----TLTSQCLTYEPTQRPSFRTIL 863
P P ++ +L L P QRP+ IL
Sbjct 378 SFPDEPIISHYGKSLIISILNPVPEQRPNLTQIL 411
>sp|D2H526|CDK12_AILME Cyclin-dependent kinase 12 OS=Ailuropoda
melanoleuca OX=9646 GN=CDK12 PE=3 SV=1
Length=1491
Score = 89.7 bits (221), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 67/215 (31%), Positives = 101/215 (47%), Gaps = 37/215 (17%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958
+GEG +G+V Y + TGE+VA+K ++ D + G+ +EI ILR L H
Sbjct 734 IGEGTYGQV----YKAKDKDTGELVALKKVRLD---NEKEGFPITAIREIKILRQLIHRS 786
Query 959 IIKYKGCCEDQGEK--------SLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQI 1007
++ K D+ + + LV EY+ +G L L S + F +Q+
Sbjct 787 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSED--HIKSFMKQL 844
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED----GDS 1063
EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ Y E
Sbjct 845 MEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLAR-------LYNSEESRPYTNKV 897
Query 1064 PVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096
WY P L E ++ A DVWS G L EL T
Sbjct 898 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFT 932
Score = 35.8 bits (81), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 16/129 (12%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILL 742
+V EY++H D+ E G V + + + +QL L Y KN +H ++ NILL
Sbjct 812 LVFEYMDH---DLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILL 868
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKW 798
G IKL+D G+ S E R ++ W P L G + A+D W
Sbjct 869 NNSGQ-------IKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVW 921
Query 799 GFGATLLEI 807
G L E+
Sbjct 922 SCGCILGEL 930
>sp|Q9SJT0|Y2214_ARATH Probable receptor-like protein kinase At2g21480
OS=Arabidopsis thaliana OX=3702 GN=At2g21480 PE=3 SV=1
Length=871
Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 71/203 (35%), Positives = 96/203 (47%), Gaps = 24/203 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHEHI 959
+G G FG V + D DGT VA+K PQ G + EI +L L H H+
Sbjct 531 IGVGGFGNVYIGTID---DGT--QVAIKR----GNPQSEQGITEFHTEIQMLSKLRHRHL 581
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAYLH- 1015
+ G C++ E + LV EY+ G RD+L ++ Q L G+ YLH
Sbjct 582 VSLIGYCDENAE--MILVYEYMSNGPFRDHLYGKNLSPLTWKQRLEICIGAARGLHYLHT 639
Query 1016 --AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072
AQ IHRD+ + N+LLD + K+ DFGL+K V G + G F Y PE
Sbjct 640 GTAQGIIHRDVKSTNILLDEALVAKVADFGLSKDVAFGQNHVSTAVKGS---FGYLDPEY 696
Query 1073 LKEYKFYYASDVWSFGVTLYELL 1095
+ + SDV+SFGV L E L
Sbjct 697 FRRQQLTDKSDVYSFGVVLLEAL 719
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 68/297 (23%), Positives = 117/297 (39%), Gaps = 39/297 (13%)
Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651
LS L + T+ + V G G+ G +DD +V +K +P
Sbjct 515 LSELQEVTKNFDASEIIGVGGFGNVYIGTIDDG------------TQVAIKRGNPQSEQG 562
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711
F+ ++S++ H HL + G C E I+V EY+ +GP L + P+ WK
Sbjct 563 ITEFHTEIQMLSKLRHRHLVSLIGYCDENAEMILVYEYMSNGPFRDHLYG-KNLSPLTWK 621
Query 712 --MVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ + A L YL + ++H +V NILL L + F D G
Sbjct 622 QRLEICIGAARGLHYLHTGTAQGIIHRDVKSTNILLDE-ALVAKVADFGLSKDVAFGQNH 680
Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE-IC----FDGEAPLQSRSPS 821
+S + +L PE L+ D + FG LLE +C + + P + + +
Sbjct 681 VSTAVK-GSFGYLDPEYFR--RQQLTDKSDVYSFGVVLLEALCARPAINPQLPREQVNLA 737
Query 822 EKEHFYQRQ---HRLPEP---------SCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
E ++++ ++ +P S + A +CL RP+ +L +L
Sbjct 738 EWAMLWKQKGLLEKIIDPHLVGAVNPESMKKFAEAAEKCLADYGVDRPTMGDVLWNL 794
>sp|O64793|Y1675_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g67520 OS=Arabidopsis thaliana OX=3702
GN=At1g67520 PE=2 SV=3
Length=818
Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 75/201 (37%), Positives = 101/201 (50%), Gaps = 18/201 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG V Y N GE VA+K L G Q +K E ++ L H ++++
Sbjct 502 LGEGGFGPV--YKGKLLN---GEEVAIKRLSLASG-QGLVEFKNEAILIAKLQHTNLVQV 555
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLF--AQQICEGMAYLHAQ- 1017
GCC ++ EK L+ EY+ SL +L P L L F + I +G+ YLH
Sbjct 556 LGCCIEKDEK--MLIYEYMQNKSLDYFLFDPLRKNVLDWTLRFRIMEGIIQGLLYLHKYS 613
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074
IHRD+ A N+LLD D KI DFGLA+ G E R + F Y +PE +
Sbjct 614 RLKVIHRDIKASNILLDEDMNPKISDFGLARIF--GAEETRANTKRVAGTFGYMSPEYFR 671
Query 1075 EYKFYYASDVWSFGVTLYELL 1095
E F SDV+SFGV + E++
Sbjct 672 EGLFSAKSDVFSFGVLMLEII 692
Score = 52.4 bits (124), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 21/193 (11%)
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
P+ G+ E V +K L + + F A L++++ HT+L V G C+ E ++
Sbjct 509 PVYKGKLLNGE-EVAIKRLSLASGQGLVEFKNEAILIAKLQHTNLVQVLGCCIEKDEKML 567
Query 686 VTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNI 740
+ EY+++ LD +L + W + + + + L YL + ++H ++ NI
Sbjct 568 IYEYMQNKSLDYFLFDPLRKNVLDWTLRFRIMEGIIQGLLYLHKYSRLKVIHRDIKASNI 627
Query 741 LLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIP----WLAPECLPGGANSLSTA 794
L L E +P K+SD G+ GA +R+ +++PE G S
Sbjct 628 L-----LDEDMNP--KISDFGLARIFGAEETRANTKRVAGTFGYMSPEYFREGL--FSAK 678
Query 795 MDKWGFGATLLEI 807
D + FG +LEI
Sbjct 679 SDVFSFGVLMLEI 691
>sp|Q5ZJB4|IKKA_CHICK Inhibitor of nuclear factor kappa-B kinase
subunit alpha OS=Gallus gallus OX=9031 GN=CHUK PE=2 SV=1
Length=759
Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 66/212 (31%), Positives = 104/212 (49%), Gaps = 25/212 (12%)
Query 899 KIRD-LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
++RD LG G FG V LY + TG VA+K+ + + +++ W EIDI++ L H
Sbjct 30 EMRDRLGTGGFGNVCLY----QHQDTGARVAIKSCRLELSVKNKDRWCHEIDIMKKLNHP 85
Query 958 HIIKYKGCCEDQGEKSL------QLVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQI 1007
++++ CE E + L MEY G LR L P + GL +Q+L I
Sbjct 86 NVVR---ACEVPEEMNFLVNDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDI 142
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDND--RLV-KIGDFGLAKAVPEGHEYYRVREDGDSP 1064
G+ YLH IHRDL N++L ++ +++ KI D G AK + +G +
Sbjct 143 GSGIQYLHENRIIHRDLKPENIVLQDEGGKIIHKIIDLGYAKDLDQG----SLCTSFVGT 198
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+ + APE + + D WSFG ++E +
Sbjct 199 LQYLAPELFENKSYSVTVDYWSFGTMVFECIA 230
>sp|Q2ULU3|STE20_ASPOR Serine/threonine-protein kinase ste20 OS=Aspergillus
oryzae (strain ATCC 42149 / RIB 40) OX=510516
GN=ste20 PE=3 SV=1
Length=848
Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 57/208 (27%), Positives = 102/208 (49%), Gaps = 14/208 (7%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DPT K Y + +G+G G V + ++GTG VA+K + D P+ + E
Sbjct 562 DPT---KMYYN-LNKIGQGASGGV----FTAYHNGTGSCVAIKQMNLDLQPK-KDLIINE 612
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +++ H++I+ + + L +VMEY+ GSL D + + + Q+ ++
Sbjct 613 IIVMKDSKHKNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMSEGQIAAVCRET 670
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
G+ +LH++ IHRD+ + N+LL D +K+ DFG + + H R +W
Sbjct 671 LNGLQHLHSKGVIHRDIKSDNILLSLDGNIKLTDFGFCAQINDSHNK---RNTMVGTPYW 727
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095
APE + ++ D+WS G+ E++
Sbjct 728 MAPEVVTRKEYGRKVDIWSLGIMAIEMI 755
Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 42/165 (25%), Positives = 69/165 (42%), Gaps = 18/165 (11%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719
+M H ++ + G + +V EY+E G L DV +A V ++
Sbjct 615 VMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVVTFNIMSEGQIA---AVCRETL 671
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERVER 775
+ L +L +K ++H ++ NILL+ G IKL+D G + R V
Sbjct 672 NGLQHLHSKGVIHRDIKSDNILLSLDG-------NIKLTDFGFCAQINDSHNKRNTMVGT 724
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
W+APE + +D W G +E+ +GE P + SP
Sbjct 725 PYWMAPEVV--TRKEYGRKVDIWSLGIMAIEM-IEGEPPYLTESP 766
>sp|Q8GZ99|HPCA1_ARATH Leucine-rich repeat receptor protein kinase
HPCA1 OS=Arabidopsis thaliana OX=3702 GN=HPCA1 PE=1 SV=1
Length=953
Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 62/181 (34%), Positives = 96/181 (53%), Gaps = 12/181 (7%)
Query 923 TGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
G+++A+K +A G Q +K EI++L ++H+++++ G C D+ E+ LV EY+
Sbjct 652 NGQLIAIK--RAQQGSLQGGLEFKTEIELLSRVHHKNVVRLLGFCFDRNEQ--MLVYEYI 707
Query 982 PLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDR 1035
GSL+D L S + + L A +G+AYLH IHRD+ + N+LLD +
Sbjct 708 SNGSLKDSLSGKSGIRLDWTRRLKIALGSGKGLAYLHELADPPIIHRDIKSNNILLDENL 767
Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
K+ DFGL+K V + E V + + PE + SDV+ FGV L ELL
Sbjct 768 TAKVADFGLSKLVGD-PEKTHVTTQVKGTMGYLDPEYYMTNQLTEKSDVYGFGVVLLELL 826
Query 1096 T 1096
T
Sbjct 827 T 827
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 64/289 (22%), Positives = 114/289 (39%), Gaps = 60/289 (21%)
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW- 710
L F L+S+V H ++ + G C E ++V EY+ +G L L + G + + W
Sbjct 669 GLEFKTEIELLSRVHHKNVVRLLGFCFDRNEQMLVYEYISNGSLKDSLSGKSG-IRLDWT 727
Query 711 -KMVVAQQLASALSY---LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--L 764
++ +A L+Y L + ++H ++ NILL A K++D G+ +
Sbjct 728 RRLKIALGSGKGLAYLHELADPPIIHRDIKSNNILLDENLTA-------KVADFGLSKLV 780
Query 765 GALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
G + ++ +L PE N L+ D +GFG LLE+ L RSP
Sbjct 781 GDPEKTHVTTQVKGTMGYLDPEYYM--TNQLTEKSDVYGFGVVLLEL-------LTGRSP 831
Query 821 SEKEHFYQRQHRLPEPSCPQL------------------------ATLTSQCLTYEPTQR 856
E+ + R+ + L L +C+ E R
Sbjct 832 IERGKYVVREVKTKMNKSRSLYDLQELLDTTIIASSGNLKGFEKYVDLALRCVEEEGVNR 891
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
PS +++++ N+ + +NP+ SD + Y I+ G+
Sbjct 892 PSMGEVVKEI-----ENIMQLAGLNPN---SDSATSSRTYEDAIKGSGD 932
>sp|E1BB50|CDK12_BOVIN Cyclin-dependent kinase 12 OS=Bos taurus
OX=9913 GN=CDK12 PE=3 SV=1
Length=1264
Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 67/213 (31%), Positives = 101/213 (47%), Gaps = 33/213 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958
+GEG +G+V Y + TGE+VA+K ++ D + G+ +EI ILR L H
Sbjct 733 IGEGTYGQV----YKAKDKDTGELVALKKVRLD---NEKEGFPITAIREIKILRQLIHRS 785
Query 959 IIKYKGCCEDQGEK--------SLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQI 1007
++ K D+ + + LV EY+ +G L L S + F +Q+
Sbjct 786 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSED--HIKSFMKQL 843
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK--AVPEGHEYYRVREDGDSPV 1065
EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ E Y
Sbjct 844 MEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYT-----NKVIT 898
Query 1066 FWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096
WY P L E ++ A DVWS G L EL T
Sbjct 899 LWYRPPELLLGEERYTPAIDVWSCGCILGELFT 931
Score = 36.2 bits (82), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 16/129 (12%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILL 742
+V EY++H D+ E G V + + + +QL L Y KN +H ++ NILL
Sbjct 811 LVFEYMDH---DLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILL 867
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKW 798
G IKL+D G+ S E R ++ W P L G + A+D W
Sbjct 868 NNSGQ-------IKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVW 920
Query 799 GFGATLLEI 807
G L E+
Sbjct 921 SCGCILGEL 929
>sp|Q6BRY2|PHO85_DEBHA Negative regulator of the PHO system OS=Debaryomyces
hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394
/ JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=PHO85 PE=3
SV=2
Length=330
Score = 85.9 bits (211), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 61/206 (30%), Positives = 100/206 (49%), Gaps = 17/206 (8%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+++ LGEG + V Y N G++VA+K + D S +EI +++ L H
Sbjct 8 FQQLEKLGEGTYATV----YKGRNRTNGQLVALKEINLDSEEGTPSTAIREISLMKELDH 63
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----SIGLAQLLLFAQQICEGMA 1012
E+I+ E L LV E++ L+ Y+ H ++ L + F Q+ +G+
Sbjct 64 ENIVTLYDVI--HTENKLTLVFEFMD-KDLKKYMEAHGNQGALDLKIVKSFIFQLLKGIM 120
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APE 1071
+ H +HRDL +N+L++N +K+GDFGLA+A + + WY AP+
Sbjct 121 FCHDNRVLHRDLKPQNLLINNKGELKLGDFGLARAFGIPFNTF----SNEVVTLWYRAPD 176
Query 1072 CLKEYKFYYAS-DVWSFGVTLYELLT 1096
L + Y AS D+WS G E+ T
Sbjct 177 VLLGSRAYTASIDIWSAGCIFAEMCT 202
Score = 38.9 bits (89), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 48/227 (21%), Positives = 93/227 (41%), Gaps = 38/227 (17%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ QL LG+GT VY+GR R GQ + + LD
Sbjct 7 QFQQLEKLGEGTYATVYKGR----------------------NRTNGQLVALKEINLDSE 44
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
+ A E SLM ++ H ++ ++ V + +V E+++ L ++
Sbjct 45 EGTPSTAIREI-SLMKELDHENIVTLYDVIHTENKLTLVFEFMDKD-LKKYMEAHGNQGA 102
Query 708 MAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV--- 762
+ K+V + QL + + + ++H ++ +N+L+ G +KL D G+
Sbjct 103 LDLKIVKSFIFQLLKGIMFCHDNRVLHRDLKPQNLLINNKGE-------LKLGDFGLARA 155
Query 763 -GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
G+ + V + + AP+ L G + + + ++D W G E+C
Sbjct 156 FGIPFNTFSNEVVTLWYRAPDVLLG-SRAYTASIDIWSAGCIFAEMC 201
>sp|Q05006|CDC22_MEDSA Cell division control protein 2 homolog
2 OS=Medicago sativa OX=3879 GN=CDC2B PE=2 SV=1
Length=294
Score = 85.1 bits (209), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 65/208 (31%), Positives = 102/208 (49%), Gaps = 20/208 (10%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYH 956
+K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ + H
Sbjct 5 EKVEKIGEGTYGVV----YKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLG--SLRDYLPRHSIGLAQLLLFAQQICEGMAYL 1014
+I++ + EK L LV EY+ L D P + Q+ +F QI G+AY
Sbjct 61 RNIVRLQDVV--HSEKRLYLVFEYLDLDLKKFMDSSPEFAKDQRQIKMFLYQILCGIAYC 118
Query 1015 HAQHYIHRDLAARNVLLD-NDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070
H+ +HRDL +N+L+D + VK+ DFGLA+A +P + V WY AP
Sbjct 119 HSHRVLHRDLKPQNLLIDRSSNAVKLADFGLARAFGIPVRTFTHEV------VTLWYRAP 172
Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTH 1097
E L + Y DVWS G E++
Sbjct 173 EILLGSRHYSTPVDVWSVGCIFAEMINQ 200
>sp|P34331|PLK1_CAEEL Serine/threonine-protein kinase plk-1 OS=Caenorhabditis
elegans OX=6239 GN=plk-1 PE=1 SV=3
Length=649
Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 73/218 (33%), Positives = 110/218 (50%), Gaps = 14/218 (6%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQH 940
P+ PA Y +K R LG+G F +CY+ TN T E+VA K + K+ Q+
Sbjct 23 PEVPALIADKDRGTYYEKGRFLGKGGFA----HCYELTNRATREVVAGKVVPKSMLVKQY 78
Query 941 RSGW--KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGL 997
+ + I I R L H +I+K ED ++ + +E SL + + R ++
Sbjct 79 QRDKVDNERILIHRELGHINIVKLFNFFEDN--LNVYITLELCARRSLMELHKRRKAVTE 136
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ F QI +G+ YLH + IHRD+ N+ L++D +VKIGDFGLA V G E R
Sbjct 137 PEARYFTHQIVDGVLYLHDLNIIHRDMKLGNLFLNDDLVVKIGDFGLATTV-NGDE--RK 193
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+ +P + APE L + + D+W+ G LY LL
Sbjct 194 KTLCGTPN-YIAPEVLNKAGHSFEVDIWAVGCILYILL 230
Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 43/172 (25%), Positives = 77/172 (45%), Gaps = 16/172 (9%)
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
L + R V Q+ + YL + N++H R++ L L L + +K+
Sbjct 127 LHKRRKAVTEPEARYFTHQIVDGVLYLHDLNIIH-----RDMKLGNLFLNDDL--VVKIG 179
Query 759 DPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
D G+ ++ +ER + + ++APE L +S +D W G L + F G+ P
Sbjct 180 DFGLAT-TVNGDERKKTLCGTPNYIAPEVLNKAGHSFE--VDIWAVGCILYILLF-GQPP 235
Query 815 LQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+S+S E + +P + A+L + L EPT+RP+ + + RD
Sbjct 236 FESKSLEETYSRIRHNNYTIPSIATQPAASLIRKMLDPEPTRRPTAKQVQRD 287
>sp|Q9R0A5|NEK3_MOUSE Serine/threonine-protein kinase Nek3 OS=Mus
musculus OX=10090 GN=Nek3 PE=1 SV=2
Length=511
Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 73/270 (27%), Positives = 125/270 (46%), Gaps = 29/270 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+R +G+G FG+ L + +N T M ++ LK+D ++E +L + H +I
Sbjct 7 LRVIGQGSFGRALLVLQESSNQ-TFAMKEIRLLKSDTQTS-----RKEAVLLAKMKHPNI 60
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLHA 1016
+ +K E +G L +VMEY G L + + L +L + QIC G+ ++H
Sbjct 61 VAFKESFEAEG--YLYIVMEYCDGGDLMQRIKQQKGKLFPEDTILNWFIQICLGVNHIHK 118
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ +HRD+ ++NV L ++ VK+GDFG A+ + + +P ++ PE +
Sbjct 119 RRVLHRDIKSKNVFLTHNGKVKLGDFGSARLLSSPMAFACTYV--GTP-YYVPPEIWENL 175
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+ SD+WS G LYEL Q+ K L ++ I QG + P
Sbjct 176 PYNNKSDIWSLGCILYELCALKHPFQANSWKNL-ILKICQGPIH--------------PL 220
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
P C++ L+K + S RP+ L+
Sbjct 221 PALYSCKLQGLVKQMLKRNPSHRPSATTLL 250
>sp|O54748|STK3_RAT Serine/threonine-protein kinase 3 OS=Rattus
norvegicus OX=10116 GN=Stk3 PE=1 SV=1
Length=491
Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 56/197 (28%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V + + +G++VA+K + + Q +EI I++ ++
Sbjct 30 LEKLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDVQE---IIKEISIMQQCDSPYV 82
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ + +G+ YLH
Sbjct 83 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFM 140
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 141 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVIQEIG 197
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 198 YNCVADIWSLGITSIEM 214
>sp|Q4G3H4|IKKA_DANRE Inhibitor of nuclear factor kappa-B kinase
subunit alpha OS=Danio rerio OX=7955 GN=chuk PE=1 SV=1
Length=758
Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 64/202 (32%), Positives = 96/202 (48%), Gaps = 19/202 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V LY N T E +AVK + + +++ W + I I++ L H +++
Sbjct 21 LGTGGFGHVYLY----QNQETSEKIAVKLCRLELNSKNKDRWSRGIQIMKKLKHLNVVTA 76
Query 963 KGCCEDQGEKSLQ----LVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMAYL 1014
K E+ +L L MEY G LR L P + GL +++L + G+ YL
Sbjct 77 KDVPEEMMHIALNDLPLLAMEYCSKGDLRKLLSKPENCCGLKESEVLSLLNDVGSGIQYL 136
Query 1015 HAQHYIHRDLAARNVLLD--NDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
H IHRDL N++L N +LV KI D G AK + +G + + + APE
Sbjct 137 HENKIIHRDLKPENIVLQEINGKLVHKIIDLGYAKDLDQGS----LCTSFVGTLQYLAPE 192
Query 1072 CLKEYKFYYASDVWSFGVTLYE 1093
+ + D WSFG ++E
Sbjct 193 LFEGKSYTVTVDFWSFGTMIFE 214
>sp|Q6GM53|IKKA_XENLA Inhibitor of nuclear factor kappa-B kinase
subunit alpha OS=Xenopus laevis OX=8355 GN=chuk PE=2 SV=1
Length=743
Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 67/206 (33%), Positives = 97/206 (47%), Gaps = 24/206 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V LY N TGE+ A+K+ + + +++ W QEI I++ L H +++K
Sbjct 21 LGTGGFGNVCLY----QNRETGELKAIKSCRLELSVKNKERWCQEIQIMKRLNHPNVVK- 75
Query 963 KGCCEDQGEKSL------QLVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMA 1012
C+ E L MEY G LR L P + GL +Q+L I G+
Sbjct 76 --ACDVPPEMDFLVNDVPHLAMEYCAGGDLRKLLNKPENCCGLKESQVLNLISDIGSGIQ 133
Query 1013 YLHAQHYIHRDLAARNVLLD--NDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH IHRDL N++L N + V KI D G AK + +G + + + A
Sbjct 134 YLHENRIIHRDLKPENIVLQECNGKTVHKIIDLGYAKDLDQGS----LCTSFVGTLQYLA 189
Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095
PE + + D WSFG +E +
Sbjct 190 PELFENKPYSVTVDYWSFGTMAFECI 215
>sp|Q54QI2|Y9877_DICDI Serine/threonine-protein kinase DDB_G0283821
OS=Dictyostelium discoideum OX=44689 GN=DDB_G0283821 PE=3
SV=1
Length=941
Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 63/198 (32%), Positives = 99/198 (50%), Gaps = 15/198 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G FGKV + N TG+ A+K + K + QEI +L+TL H +I+K
Sbjct 19 VGKGAFGKV----FKALNAETGDFCAIKQIEKTIISEKQLPSIIQEIKLLQTLQHPNIVK 74
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLHAQHYI 1020
+ E + L +E++ GSL R+ LL + Q+ +G+AYLH + I
Sbjct 75 FIESYE--TSRYLYFALEFIEGGSLAKIAKRYGCFQEPLLSRYFSQVLKGLAYLHEKGVI 132
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK--EYKF 1078
HRD+ + N+L+ + ++K+ DFG + V +P FW APE ++
Sbjct 133 HRDIKSDNILITKEGVIKLADFGSCTYSAIDRKLTVV----GTP-FWMAPEVIQMDMNAR 187
Query 1079 YYASDVWSFGVTLYELLT 1096
A D+WS G TL E+LT
Sbjct 188 STACDIWSLGCTLLEMLT 205
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 34/93 (37%), Positives = 50/93 (54%), Gaps = 9/93 (10%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-VGLGALSREERVER 775
Q+ L+YL K ++H ++ NIL+ + G+ IKL+D G A+ R+ V
Sbjct 118 QVLKGLAYLHEKGVIHRDIKSDNILITKEGV-------IKLADFGSCTYSAIDRKLTVVG 170
Query 776 IP-WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
P W+APE + N+ STA D W G TLLE+
Sbjct 171 TPFWMAPEVIQMDMNARSTACDIWSLGCTLLEM 203
>sp|Q9STK6|WNK3_ARATH Probable serine/threonine-protein kinase
WNK3 OS=Arabidopsis thaliana OX=3702 GN=WNK3 PE=2 SV=1
Length=516
Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 73/216 (34%), Positives = 109/216 (50%), Gaps = 19/216 (9%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD---CGPQHRSGW 944
DPT + RY K++ LG+G F +V Y + G VA +K D C +
Sbjct 16 DPTGRYGRY-KEV--LGKGAFKEV----YRAFDQLEGIEVAWNQVKLDDKFCSSEDLDRL 68
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLF 1003
E+ +L+TL H+ IIK+ D ++ L+ E G+LR Y +H + L L +
Sbjct 69 YSEVHLLKTLKHKSIIKFYTSWIDHQHMTINLITEVFTSGNLRQYRKKHKCVDLRALKKW 128
Query 1004 AQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
++QI EG+ YLH+ IHRDL N+ ++ N VKIGD GLA + + V
Sbjct 129 SRQILEGLVYLHSHDPPVIHRDLKCDNIFINGNQGEVKIGDLGLAAILHRARSAHSVI-- 186
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+P F APE L E + D+++FG+ L EL+T
Sbjct 187 -GTPEFM-APE-LYEEDYNVLVDIYAFGMCLLELVT 219
>sp|Q852Q1|OSK4_ORYSJ Serine/threonine protein kinase OSK4 OS=Oryza
sativa subsp. japonica OX=39947 GN=OSK4 PE=1 SV=1
Length=509
Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 71/200 (36%), Positives = 97/200 (49%), Gaps = 16/200 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEH 958
R LG G FGKV + + TG VA+K L + + K+EI ILR H H
Sbjct 21 RTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKREIKILRLFIHPH 76
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
II+ + + +VMEY G L DY+ + + + QQI G+ Y H
Sbjct 77 IIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQIISGVEYCHRN 134
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL N+LLD+ VK+ DFGL+ + +GH ++ SP + APE + K
Sbjct 135 MVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGH---FLKTSCGSPNYA-APEVISG-K 189
Query 1078 FYYA--SDVWSFGVTLYELL 1095
Y DVWS GV LY LL
Sbjct 190 LYAGPEVDVWSCGVILYALL 209
>sp|B8BBT7|OSK4_ORYSI Serine/threonine protein kinase OSK4 OS=Oryza
sativa subsp. indica OX=39946 GN=OSK4 PE=3 SV=1
Length=509
Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 71/200 (36%), Positives = 97/200 (49%), Gaps = 16/200 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEH 958
R LG G FGKV + + TG VA+K L + + K+EI ILR H H
Sbjct 21 RTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKREIKILRLFIHPH 76
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
II+ + + +VMEY G L DY+ + + + QQI G+ Y H
Sbjct 77 IIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQIISGVEYCHRN 134
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL N+LLD+ VK+ DFGL+ + +GH ++ SP + APE + K
Sbjct 135 MVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGH---FLKTSCGSPNYA-APEVISG-K 189
Query 1078 FYYA--SDVWSFGVTLYELL 1095
Y DVWS GV LY LL
Sbjct 190 LYAGPEVDVWSCGVILYALL 209
>sp|Q76P07|Y7165_DICDI Probable serine/threonine-protein kinase
DDB_G0277165 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0277165
PE=3 SV=1
Length=833
Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 66/198 (33%), Positives = 99/198 (50%), Gaps = 9/198 (5%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+ LG+G GKV L + T G + K L + P R ++EI +++ + H + +
Sbjct 13 KTLGQGTTGKVKLGFHKDTGFKVGIKIINKELLIN-KPSMRRKIEREIVLMKLIDHPNAM 71
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
K E K L L++EYV G L DYL + + + L F QQI G+ Y H+++
Sbjct 72 KMYEVYET--SKYLFLILEYVEGGELFDYLVEKGGLESGEALFFFQQIIIGLEYCHSRNI 129
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
HRDL N+LL D+ +KI DFG+ V + + SP + +PE + +
Sbjct 130 CHRDLKPENLLLSGDKRIKIADFGMGSIV---RKDMLLHTSCGSP-HYASPEVVSGIDYD 185
Query 1080 -YASDVWSFGVTLYELLT 1096
+DVWS GV LY LLT
Sbjct 186 GQKADVWSCGVILYALLT 203
Score = 38.1 bits (87), Expect = 0.56, Method: Compositional matrix adjust.
Identities = 47/214 (22%), Positives = 90/214 (42%), Gaps = 30/214 (14%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
LM + H + ++ V ++ EYVE G L +L E+G + + QQ+
Sbjct 61 LMKLIDHPNAMKMYEVYETSKYLFLILEYVEGGELFDYLV-EKGGLESGEALFFFQQIII 119
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP--- 777
L Y ++N+ H ++ N+LL+ IK++D G+G++ R++ +
Sbjct 120 GLEYCHSRNICHRDLKPENLLLS-------GDKRIKIAD--FGMGSIVRKDMLLHTSCGS 170
Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR--- 832
+ +PE + G + D W G L A L + P + E+ + ++
Sbjct 171 PHYASPEVV-SGIDYDGQKADVWSCGVILY-------ALLTGKLPFDDENIRRLLNKVKN 222
Query 833 ----LPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
+P L ++ LT +P++R S + I
Sbjct 223 GAFSMPPYIHKDAQDLLTKMLTVDPSKRISIKEI 256
>sp|Q9SX31|PERK9_ARATH Proline-rich receptor-like protein kinase
PERK9 OS=Arabidopsis thaliana OX=3702 GN=PERK9 PE=1 SV=1
Length=708
Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 71/209 (34%), Positives = 103/209 (49%), Gaps = 20/209 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG C G +VAVK LK G R +K E++ L ++H H++
Sbjct 383 LGEGGFG-----CVYKGILPDGRVVAVKQLKIGGGQGDRE-FKAEVETLSRIHHRHLVSI 436
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ--- 1017
G C G++ L L+ +YV L +L + + A + A G+AYLH
Sbjct 437 VGHC-ISGDRRL-LIYDYVSNNDLYFHLHGEKSVLDWATRVKIAAGAARGLAYLHEDCHP 494
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKEY 1076
IHRD+ + N+LL+++ ++ DFGLA+ + + + R G F Y APE
Sbjct 495 RIIHRDIKSSNILLEDNFDARVSDFGLARLALDCNTHITTRVIG---TFGYMAPEYASSG 551
Query 1077 KFYYASDVWSFGVTLYELLTH---CDSSQ 1102
K SDV+SFGV L EL+T D+SQ
Sbjct 552 KLTEKSDVFSFGVVLLELITGRKPVDTSQ 580
Score = 51.2 bits (121), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 45/182 (25%), Positives = 77/182 (42%), Gaps = 18/182 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F +S++ H HL + G C+ G +++ +YV + L L E+ + A ++ +
Sbjct 418 FKAEVETLSRIHHRHLVSIVGHCISGDRRLLIYDYVSNNDLYFHLHGEKSVLDWATRVKI 477
Query 715 AQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771
A A L+YL ++H ++ NILL A ++SD G+ AL
Sbjct 478 AAGAARGLAYLHEDCHPRIIHRDIKSSNILLEDNFDA-------RVSDFGLARLALDCNT 530
Query 772 RVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ ++APE G L+ D + FG LLE+ G P+ + P E
Sbjct 531 HITTRVIGTFGYMAPEYASSG--KLTEKSDVFSFGVVLLEL-ITGRKPVDTSQPLGDESL 587
Query 827 YQ 828
+
Sbjct 588 VE 589
>sp|Q07292|KRAF1_CAEEL Raf homolog serine/threonine-protein kinase
OS=Caenorhabditis elegans OX=6239 GN=lin-45 PE=1 SV=2
Length=813
Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 72/280 (26%), Positives = 125/280 (45%), Gaps = 30/280 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y GT VA+K L D P + +K E+ +L+ H +++
Sbjct 487 VGSGSFGTV----YRGEFFGT---VAIKKLNVVDPTPSQMAAFKNEVAVLKKTRHLNVLL 539
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G E + ++ ++ SL ++ PR + ++ +Q+ GM YLH++
Sbjct 540 FMGWVR---EPEIAIITQWCEGSSLYRHIHVQEPRVEFEMGAIIDILKQVSLGMNYLHSK 596
Query 1018 HYIHRDLAARNV-LLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLK- 1074
+ IHRDL N+ L+D+ VKIGDFGLA + + ++ + W APE ++
Sbjct 597 NIIHRDLKTNNIFLMDDMSTVKIGDFGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRM 656
Query 1075 --EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + SDV+SFG+ +YE+L + L I + + R +
Sbjct 657 QDDNPYTPQSDVYSFGICMYEIL----------SSHLPYSNINNRDQILFMVGRGYLRPD 706
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
R P + L NC + + RP F ++ L+ +
Sbjct 707 RSKIRHDTPKSMLKLYDNCIMFDRNERPVFGEVLERLRDI 746
Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/246 (22%), Positives = 104/246 (42%), Gaps = 31/246 (13%)
Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVW 698
L V+DP+ +A AF +++ + H ++ G VR PE ++T++ E L +
Sbjct 509 LNVVDPTPSQMA-AFKNEVAVLKKTRHLNVLLFMG-WVREPEIAIITQWCEGSSLYRHIH 566
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
++ R M + + +Q++ ++YL +KN++H ++ NI L +K+
Sbjct 567 VQEPRVEFEMGAIIDILKQVSLGMNYLHSKNIIHRDLKTNNIFLM------DDMSTVKIG 620
Query 759 DPGVGLGALSREERVE----------RIPWLAPECLP-GGANSLSTAMDKWGFGATLLEI 807
D GL + + V I W+APE + N + D + FG + EI
Sbjct 621 D--FGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGICMYEI 678
Query 808 CFDGEAPLQSRSPSEKEHF-----YQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFR 860
P + + ++ F Y R R + + + L C+ ++ +RP F
Sbjct 679 -LSSHLPYSNINNRDQILFMVGRGYLRPDRSKIRHDTPKSMLKLYDNCIMFDRNERPVFG 737
Query 861 TILRDL 866
+L L
Sbjct 738 EVLERL 743
>sp|Q9GRT1|MKK4_LEIME Putative mitogen-activated protein kinase
kinase 4 OS=Leishmania mexicana OX=5665 GN=MKK4 PE=1 SV=2
Length=350
Score = 85.9 bits (211), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 63/216 (29%), Positives = 113/216 (52%), Gaps = 18/216 (8%)
Query 885 PASDPTVFHKRYLKKIR---DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH- 940
P SD V +K + +R +LG+G GKV + + T GE A+K + D
Sbjct 59 PKSD-AVMNKIKFEDLRIGSELGKGSQGKVRVAQHKLT----GEKYAMKYIAFDGDSDDM 113
Query 941 RSGWKQEIDILRTLYHEHIIK-YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ 999
RS + E+ + + H +++ Y+ D L +V+EY+ G++ + + RH G ++
Sbjct 114 RSALEAELRQVAAVKHHNVVSSYEAFFRD---GRLYIVLEYMDCGTMNNLIDRHPEGFSE 170
Query 1000 LLL--FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+L A+++ +G+ +LH + IHRD+ NVL + +KI DFG+AK + G + +
Sbjct 171 DMLAYIARELFKGLEFLHHLNMIHRDIKPANVLANTKGEIKISDFGVAKTL-SGGDLQTL 229
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
G P + +PE ++ + + SD+WS G+T+ E
Sbjct 230 SAQGSVP--YMSPERIQSKPYSFNSDIWSAGLTIAE 263
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 43/191 (23%), Positives = 77/191 (40%), Gaps = 14/191 (7%)
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
G++ + D D+ A ++ V H ++ + R +V EY++ G
Sbjct 96 GEKYAMKYIAFDGDSDDMRSALEAELRQVAAVKHHNVVSSYEAFFRDGRLYIVLEYMDCG 155
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
++ + R +A++L L +L + N++H ++ N+L T
Sbjct 156 TMNNLIDRHPEGFSEDMLAYIARELFKGLEFLHHLNMIHRDIKPANVL-------ANTKG 208
Query 754 FIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
IK+SD GV G L +P+++PE + S ++ D W G T+ E F
Sbjct 209 EIKISDFGVAKTLSGGDLQTLSAQGSVPYMSPERIQSKPYSFNS--DIWSAGLTIAECAF 266
Query 810 DGEAPLQSRSP 820
E P S P
Sbjct 267 R-EYPFASLKP 276
>sp|Q9LQQ8|PBL5_ARATH Probable serine/threonine-protein kinase
PBL5 OS=Arabidopsis thaliana OX=3702 GN=PBL5 PE=2 SV=1
Length=423
Score = 87.0 bits (214), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 89/300 (30%), Positives = 139/300 (46%), Gaps = 31/300 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FGKV + T + ++VA+K L + G Q + E+ L H +++K
Sbjct 109 LGEGGFGKV----FKGTIEKLDQVVAIKQLDRN-GVQGIREFVVEVLTLSLADHPNLVKL 163
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017
G C +G++ L LV EY+P GSL D+L G L + A G+ YLH +
Sbjct 164 IGFCA-EGDQRL-LVYEYMPQGSLEDHLHVLPSGKKPLDWNTRMKIAAGAARGLEYLHDR 221
Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG---HEYYRVREDGDSPVFWYAPE 1071
I+RDL N+LL D K+ DFGLAK P G H RV + AP+
Sbjct 222 MTPPVIYRDLKCSNILLGEDYQPKLSDFGLAKVGPSGDKTHVSTRVM----GTYGYCAPD 277
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIA----QGQMTVLRLTE 1126
+ + SD++SFGV L EL+T + + T K L+G A + + ++ +
Sbjct 278 YAMTGQLTFKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLFKDRRNFPKMVD 337
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV-HEKYQGQAPSVFS 1185
L +G+ P + + + C + + + RP +++ L + KY +PS S
Sbjct 338 PLLQGQ---YPVRGLYQALAISAMCVQEQPTMRPVVSDVVLALNFLASSKYDPNSPSSSS 394
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 64/274 (23%), Positives = 111/274 (41%), Gaps = 35/274 (13%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K LD + F +S H +L + G C G + ++V EY+ G L+
Sbjct 129 VAIKQLDRNGVQGIREFVVEVLTLSLADHPNLVKLIGFCAEGDQRLLVYEYMPQGSLEDH 188
Query 699 LR-RERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
L G P+ W +M +A A L YL ++ + V R++ + + L E P
Sbjct 189 LHVLPSGKKPLDWNTRMKIAAGAARGLEYLHDR--MTPPVIYRDLKCSNILLGEDYQP-- 244
Query 756 KLSDPGVG-LGALSREERVE-RIPWLAPECLPGGA--NSLSTAMDKWGFGATLLEICFDG 811
KLSD G+ +G + V R+ C P A L+ D + FG LLE+
Sbjct 245 KLSDFGLAKVGPSGDKTHVSTRVMGTYGYCAPDYAMTGQLTFKSDIYSFGVVLLELITGR 304
Query 812 EAPLQSRSPSEKEH------FYQRQHRLPEPSCP------------QLATLTSQCLTYEP 853
+A +++ ++ ++ + P+ P Q +++ C+ +P
Sbjct 305 KAIDNTKTRKDQNLVGWARPLFKDRRNFPKMVDPLLQGQYPVRGLYQALAISAMCVQEQP 364
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
T RP ++ L L +P+SP+S
Sbjct 365 TMRPVVSDVVLALNFLASSKY------DPNSPSS 392
>sp|Q9LK03|PERK2_ARATH Proline-rich receptor-like protein kinase
PERK2 OS=Arabidopsis thaliana OX=3702 GN=PERK2 PE=2 SV=3
Length=717
Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 68/201 (34%), Positives = 98/201 (49%), Gaps = 18/201 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V G+ VAVK LK R ++ E+ I+ ++H H++
Sbjct 360 LGQGGFGYVFKGMLR-----NGKEVAVKQLKEGSSQGERE-FQAEVGIISRVHHRHLVAL 413
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
G C ++ LV E+VP +L +L R ++ + L A +G++YLH
Sbjct 414 VGYCIADAQR--LLVYEFVPNNTLEFHLHGKGRPTMEWSSRLKIAVGSAKGLSYLHENCN 471
Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075
IHRD+ A N+L+D K+ DFGLAK + + + R G F Y APE
Sbjct 472 PKIIHRDIKASNILIDFKFEAKVADFGLAKIASDTNTHVSTRVMG---TFGYLAPEYASS 528
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
K SDV+SFGV L EL+T
Sbjct 529 GKLTEKSDVFSFGVVLLELIT 549
Score = 51.6 bits (122), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 68/266 (26%), Positives = 104/266 (39%), Gaps = 54/266 (20%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
P PG L I +G T N +LS ++ + LGQG V++G LR
Sbjct 327 PSPGLALGLGIYQG------TFNYEELSRA---TNGFSEANLLGQGGFGYVFKGMLR--- 374
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672
G+E V +K L F ++S+V H HL
Sbjct 375 --------------------NGKE--VAVKQLKEGSSQGEREFQAEVGIISRVHHRHLVA 412
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---N 727
+ G C+ + ++V E+V + L+ L +G M W ++ +A A LSYL N
Sbjct 413 LVGYCIADAQRLLVYEFVPNNTLEFHL-HGKGRPTMEWSSRLKIAVGSAKGLSYLHENCN 471
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPE 782
++H ++ NIL+ A K++D G+ A V +LAPE
Sbjct 472 PKIIHRDIKASNILIDFKFEA-------KVADFGLAKIASDTNTHVSTRVMGTFGYLAPE 524
Query 783 CLPGGANSLSTAMDKWGFGATLLEIC 808
G L+ D + FG LLE+
Sbjct 525 YASSG--KLTEKSDVFSFGVVLLELI 548
>sp|Q852Q0|OSK3_ORYSJ Serine/threonine protein kinase OSK3 OS=Oryza
sativa subsp. japonica OX=39947 GN=OSK3 PE=1 SV=1
Length=508
Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 71/200 (36%), Positives = 97/200 (49%), Gaps = 16/200 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEH 958
R LG G FGKV + + TG VA+K L + + K+EI ILR H H
Sbjct 21 RTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKREIKILRLFIHPH 76
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
II+ + + +VMEY G L DY+ + + + QQI G+ Y H
Sbjct 77 IIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQIISGVEYCHRN 134
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL N+LLD+ VK+ DFGL+ + +GH ++ SP + APE + K
Sbjct 135 MVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGH---FLKTSCGSPNYA-APEVISG-K 189
Query 1078 FYYA--SDVWSFGVTLYELL 1095
Y DVWS GV LY LL
Sbjct 190 LYAGPEVDVWSCGVILYALL 209
>sp|A2XFF4|OSK3_ORYSI Serine/threonine protein kinase OSK3 OS=Oryza
sativa subsp. indica OX=39946 GN=OSK3 PE=3 SV=1
Length=508
Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 71/200 (36%), Positives = 97/200 (49%), Gaps = 16/200 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEH 958
R LG G FGKV + + TG VA+K L + + K+EI ILR H H
Sbjct 21 RTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKREIKILRLFIHPH 76
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
II+ + + +VMEY G L DY+ + + + QQI G+ Y H
Sbjct 77 IIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQIISGVEYCHRN 134
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL N+LLD+ VK+ DFGL+ + +GH ++ SP + APE + K
Sbjct 135 MVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGH---FLKTSCGSPNYA-APEVISG-K 189
Query 1078 FYYA--SDVWSFGVTLYELL 1095
Y DVWS GV LY LL
Sbjct 190 LYAGPEVDVWSCGVILYALL 209
>sp|Q62673|PLK1_RAT Serine/threonine-protein kinase PLK1 OS=Rattus
norvegicus OX=10116 GN=Plk1 PE=2 SV=2
Length=603
Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 76/269 (28%), Positives = 119/269 (44%), Gaps = 28/269 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEH 958
R LG+G F K C++ ++ T E+ K + P + EI I R+L H+H
Sbjct 57 RFLGKGGFAK----CFEISDSDTKEVFPGKIVPKSLLLKPHQKEKMSMEISIHRSLAHQH 112
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
++ + G ED + +V+E SL + + R ++ + + +QI G YLH
Sbjct 113 VVGFHGFFEDSD--FVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRN 170
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRDL N+ L+ D VKIGDFGLA V +E R + +P + APE L +
Sbjct 171 QVIHRDLKLGNLFLNEDLEVKIGDFGLATKVE--YEGERKKTLCGTPN-YIAPEVLSKKG 227
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ DVWS G +Y L L+G + + L+ T L + P
Sbjct 228 HSFEVDVWSIGCIMYTL----------------LVGKPPFETSCLKETYLRIKKNEYSIP 271
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L++ +T+ + RPT L+
Sbjct 272 KHINPVAASLIQKMLQTDPTARPTIHELL 300
Score = 43.9 bits (102), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 46/211 (22%), Positives = 84/211 (40%), Gaps = 16/211 (8%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+ ++H H+ HG +V E L + L + R + +Q+
Sbjct 103 SIHRSLAHQHVVGFHGFFEDSDFVFVVLELCRRRSL-LELHKRRKALTEPEARYYLRQIV 161
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776
YL ++H R++ L L L E +K+ D G+ ER + +
Sbjct 162 LGCQYLHRNQVIH-----RDLKLGNLFLNEDLE--VKIGDFGLATKVEYEGERKKTLCGT 214
Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLP 834
++APE L +S +D W G + + G+ P ++ E + ++ +P
Sbjct 215 PNYIAPEVLSKKGHSFE--VDVWSIGCIMYTLLV-GKPPFETSCLKETYLRIKKNEYSIP 271
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ P A+L + L +PT RP+ +L D
Sbjct 272 KHINPVAASLIQKMLQTDPTARPTIHELLND 302
>sp|Q8VZJ9|CRCK2_ARATH Calmodulin-binding receptor-like cytoplasmic
kinase 2 OS=Arabidopsis thaliana OX=3702 GN=CRCK2 PE=2
SV=1
Length=411
Score = 86.7 bits (213), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 67/207 (32%), Positives = 97/207 (47%), Gaps = 23/207 (11%)
Query 903 LGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHEH 958
+G+G FG V + D G+ AVK K + + EI L + H
Sbjct 125 IGQGGFGTVYKVKLRD------GKTFAVKRAKKSMHDDRQGADAEFMSEIQTLAQVTHLS 178
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH 1015
++KY G EK LV+EYV G+LRD+L ++ +A L A + + YLH
Sbjct 179 LVKYYGFVVHNDEK--ILVVEYVANGTLRDHLDCKEGKTLDMATRLDIATDVAHAITYLH 236
Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE---GHEYYRVREDGDSPVFWYA 1069
IHRD+ + N+LL + K+ DFG A+ P+ G + + G + +
Sbjct 237 MYTQPPIIHRDIKSSNILLTENYRAKVADFGFARLAPDTDSGATHVSTQVKGTAG--YLD 294
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096
PE L Y+ SDV+SFGV L ELLT
Sbjct 295 PEYLTTYQLTEKSDVYSFGVLLVELLT 321
Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 52/178 (29%), Positives = 84/178 (47%), Gaps = 15/178 (8%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAWKMV 713
F ++QV+H L +G V E I+V EYV +G L L +E + MA ++
Sbjct 164 FMSEIQTLAQVTHLSLVKYYGFVVHNDEKILVVEYVANGTLRDHLDCKEGKTLDMATRLD 223
Query 714 VAQQLASALSYLENKN---LVHGNVCGRNILLA---RLGLAEGTSPFIKLSDPGVGLGAL 767
+A +A A++YL ++H ++ NILL R +A+ F +L+ P GA
Sbjct 224 IATDVAHAITYLHMYTQPPIIHRDIKSSNILLTENYRAKVADF--GFARLA-PDTDSGAT 280
Query 768 SREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ-SRSPSEK 823
+V+ +L PE L L+ D + FG L+E+ G P++ SR E+
Sbjct 281 HVSTQVKGTAGYLDPEYLT--TYQLTEKSDVYSFGVLLVEL-LTGRRPIELSRGQKER 335
>sp|Q9C821|PEK15_ARATH Proline-rich receptor-like protein kinase
PERK15 OS=Arabidopsis thaliana OX=3702 GN=PERK15 PE=2 SV=1
Length=509
Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 68/201 (34%), Positives = 101/201 (50%), Gaps = 18/201 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V DGT +VA+K LK+ G R ++ EI + ++H H++
Sbjct 149 LGQGGFGYVHRGVL---VDGT--LVAIKQLKSGSGQGERE-FQAEIQTISRVHHRHLVSL 202
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
G C ++ LV E+VP +L +L R + ++ + A +G+AYLH
Sbjct 203 LGYCITGAQR--LLVYEFVPNKTLEFHLHEKERPVMEWSKRMKIALGAAKGLAYLHEDCN 260
Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075
IHRD+ A N+L+D+ K+ DFGLA++ + + R G F Y APE
Sbjct 261 PKTIHRDVKAANILIDDSYEAKLADFGLARSSLDTDTHVSTRIMG---TFGYLAPEYASS 317
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
K SDV+S GV L EL+T
Sbjct 318 GKLTEKSDVFSIGVVLLELIT 338
Score = 54.3 bits (129), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 79/175 (45%), Gaps = 19/175 (11%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL-RRERGHVPMAWKMV 713
F +S+V H HL + G C+ G + ++V E+V + L+ L +ER + + +M
Sbjct 184 FQAEIQTISRVHHRHLVSLLGYCITGAQRLLVYEFVPNKTLEFHLHEKERPVMEWSKRMK 243
Query 714 VAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+A A L+YL N +H +V NIL+ S KL+D G+ +L +
Sbjct 244 IALGAAKGLAYLHEDCNPKTIHRDVKAANILI-------DDSYEAKLADFGLARSSLDTD 296
Query 771 ERVE-RI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
V RI +LAPE G L+ D + G LLE+ G P+ P
Sbjct 297 THVSTRIMGTFGYLAPEYASSG--KLTEKSDVFSIGVVLLEL-ITGRRPVDKSQP 348
>sp|Q9JI10|STK3_MOUSE Serine/threonine-protein kinase 3 OS=Mus
musculus OX=10090 GN=Stk3 PE=1 SV=1
Length=497
Score = 87.4 bits (215), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 56/197 (28%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V + + +G++VA+K + + Q +EI I++ ++
Sbjct 30 LEKLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQE---IIKEISIMQQCDSPYV 82
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ + +G+ YLH
Sbjct 83 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFM 140
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 141 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 197
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 198 YNCVADIWSLGITSIEM 214
>sp|P51957|NEK4_HUMAN Serine/threonine-protein kinase Nek4 OS=Homo
sapiens OX=9606 GN=NEK4 PE=1 SV=2
Length=841
Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 62/200 (31%), Positives = 101/200 (51%), Gaps = 10/200 (5%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+R +G+G +G+V+L + DG ++ L+ + + R +QE +L L H +I
Sbjct 9 LRVVGKGSYGEVTLVKH--RRDGKQYVIKKLNLR-NASSRERRAAEQEAQLLSQLKHPNI 65
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLHA 1016
+ YK E G+ L +VM + G L L L Q++ + QI + YLH
Sbjct 66 VTYKESWEG-GDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHE 124
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+H +HRDL +NV L ++K+GD G+A+ V E H G +P ++ +PE
Sbjct 125 KHILHRDLKTQNVFLTRTNIIKVGDLGIAR-VLENHCDMASTLIG-TP-YYMSPELFSNK 181
Query 1077 KFYYASDVWSFGVTLYELLT 1096
+ Y SDVW+ G +YE+ T
Sbjct 182 PYNYKSDVWALGCCVYEMAT 201
Score = 43.9 bits (102), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 52/220 (24%), Positives = 95/220 (43%), Gaps = 20/220 (9%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEYVEHGPLDVWLRRERGHVPMAWK 711
A + A L+SQ+ H ++ + G + ++ V + E G L L+ ++G + +
Sbjct 49 AAEQEAQLLSQLKHPNI-VTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQL-LPEN 106
Query 712 MVVA--QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
VV Q+A AL YL K+++H ++ +N+ L R + IK+ D G+ +
Sbjct 107 QVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNI-------IKVGDLGIARVLENH 159
Query 770 EERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
+ + +++PE + + D W G + E+ A S
Sbjct 160 CDMASTLIGTPYYMSPELFSNKPYNYKS--DVWALGCCVYEMATLKHAFNAKDMNSLVYR 217
Query 826 FYQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ + +P P+LA L L+ P +RPS R+ILR
Sbjct 218 IIEGKLPPMPRDYSPELAELIRTMLSKRPEERPSVRSILR 257
>sp|Q5R7G9|NUAK2_PONAB NUAK family SNF1-like kinase 2 OS=Pongo
abelii OX=9601 GN=NUAK2 PE=2 SV=1
Length=628
Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 62/200 (31%), Positives = 100/200 (50%), Gaps = 15/200 (8%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHE 957
+ LG+G +GKV + +G +VA+K+++ D Q ++EI+I+ +L H
Sbjct 56 LETLGKGTYGKVK-----KARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHP 110
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHA 1016
HII E+ + + +VMEY G L DY+ R + + F +QI + Y H
Sbjct 111 HIIAIHEVFENSSK--IVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQ 168
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL N+LLD + +KI DFGL+ H+ ++ SP++ +PE +
Sbjct 169 NRVVHRDLKLENILLDANGNIKIADFGLSNLY---HQGKFLQTFCGSPLY-ASPEIVNGK 224
Query 1077 KFYYAS-DVWSFGVTLYELL 1095
+ D WS GV LY L+
Sbjct 225 PYTGPEVDSWSLGVLLYILV 244
Score = 41.2 bits (95), Expect = 0.066, Method: Compositional matrix adjust.
Identities = 41/159 (26%), Positives = 65/159 (41%), Gaps = 15/159 (9%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
+MS ++H H+ +H V + ++V EY G L ++ ER + +Q+ S
Sbjct 103 IMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYI-SERQQLSEREARHFFRQIVS 161
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---- 776
A+ Y +VH ++ NILL G IK++D GL L + + +
Sbjct 162 AVHYCHQNRVVHRDLKLENILLDANG-------NIKIAD--FGLSNLYHQGKFLQTFCGS 212
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
P A + G +D W G LL I G P
Sbjct 213 PLYASPEIVNGKPYTGPEVDSWSLG-VLLYILVHGTMPF 250
>sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo
sapiens OX=9606 GN=NUAK2 PE=1 SV=1
Length=628
Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 62/200 (31%), Positives = 100/200 (50%), Gaps = 15/200 (8%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHE 957
+ LG+G +GKV + +G +VA+K+++ D Q ++EI+I+ +L H
Sbjct 56 LETLGKGTYGKVK-----KARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHP 110
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHA 1016
HII E+ + + +VMEY G L DY+ R + + F +QI + Y H
Sbjct 111 HIIAIHEVFENSSK--IVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQ 168
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL N+LLD + +KI DFGL+ H+ ++ SP++ +PE +
Sbjct 169 NRVVHRDLKLENILLDANGNIKIADFGLSNLY---HQGKFLQTFCGSPLY-ASPEIVNGK 224
Query 1077 KFYYAS-DVWSFGVTLYELL 1095
+ D WS GV LY L+
Sbjct 225 PYTGPEVDSWSLGVLLYILV 244
Score = 41.2 bits (95), Expect = 0.064, Method: Compositional matrix adjust.
Identities = 41/159 (26%), Positives = 65/159 (41%), Gaps = 15/159 (9%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
+MS ++H H+ +H V + ++V EY G L ++ ER + +Q+ S
Sbjct 103 IMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYI-SERQQLSEREARHFFRQIVS 161
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---- 776
A+ Y +VH ++ NILL G IK++D GL L + + +
Sbjct 162 AVHYCHQNRVVHRDLKLENILLDANG-------NIKIAD--FGLSNLYHQGKFLQTFCGS 212
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
P A + G +D W G LL I G P
Sbjct 213 PLYASPEIVNGKPYTGPEVDSWSLG-VLLYILVHGTMPF 250
>sp|F4JBP3|ATG1B_ARATH Serine/threonine-protein kinase ATG1b OS=Arabidopsis
thaliana OX=3702 GN=ATG1B PE=2 SV=1
Length=711
Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 74/235 (31%), Positives = 118/235 (50%), Gaps = 29/235 (12%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHI 959
R +G G F V ++ + G +VA+K + A + + EI ILR + H +I
Sbjct 24 RQIGSGSFSVV----WEGRHLVHGTVVAIKEIAMARLNKKLQESLMSEIIILRKINHPNI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018
I++ E G+ + LV+EY G L Y+ +H S+ A F Q+ G+ L +
Sbjct 80 IRFIDMIEAPGK--INLVLEYCKGGDLSMYIHKHGSVPEATAKHFMLQLAAGLQVLRDNN 137
Query 1019 YIHRDLAARNVLL---DNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL +N+LL DND +KI DFG A+++ P G + E + APE ++
Sbjct 138 IIHRDLKPQNLLLSTDDNDAALKIADFGFARSLQPRG-----LAETLCGSPLYMAPEIMQ 192
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM--TVLRLTEL 1127
K+ +D+WS G L++L+T ++P T G +Q Q+ ++R TEL
Sbjct 193 LQKYDAKADLWSVGAILFQLVT----GRTPFT------GNSQIQLLQNIIRSTEL 237
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 50/208 (24%), Positives = 89/208 (43%), Gaps = 18/208 (9%)
Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
++ +++H ++ F+ + G N +V EY + G L +++ + G VP A QLA
Sbjct 70 ILRKINHPNIIRFIDMIEAPGKIN-LVLEYCKGGDLSMYIHKH-GSVPEATAKHFMLQLA 127
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR---EERVERI 776
+ L L + N++H ++ +N+LL+ + +K++D G R E
Sbjct 128 AGLQVLRDNNIIHRDLKPQNLLLS----TDDNDAALKIADFGFARSLQPRGLAETLCGSP 183
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836
++APE + D W GA L ++ G P S + R L P
Sbjct 184 LYMAPEIMQ--LQKYDAKADLWSVGAILFQLV-TGRTPFTGNSQIQLLQNIIRSTELHFP 240
Query 837 S-CPQLAT----LTSQCLTYEPTQRPSF 859
+ C L+T L + L P +R +F
Sbjct 241 ADCRDLSTDCKDLCQKLLRRNPVERLTF 268
>sp|O22808|LYK5_ARATH Protein LYK5 OS=Arabidopsis thaliana OX=3702
GN=LYK5 PE=2 SV=1
Length=664
Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 69/264 (26%), Positives = 122/264 (46%), Gaps = 24/264 (9%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
G+ AVK +K D EI++L+ L H +II+ G C +G LV EY
Sbjct 389 GDDAAVKVIKGDVS-------SSEINLLKKLNHSNIIRLSGFCIREGTS--YLVFEYSEN 439
Query 984 GSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLV 1037
GS+ D+L + S+ Q + A+ + E + YLH +IH++L + N+LLD++
Sbjct 440 GSISDWLHSSGKKSLTWKQRVEIARDVAEALDYLHNYITPPHIHKNLESTNILLDSNFRA 499
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT- 1096
KI +FG+A+ + EG ++ + + APE ++ DV++FGV + ELL+
Sbjct 500 KIANFGVARILDEGDLDLQLTRHVEGTQGYLAPEYVENGVITSKLDVFAFGVAVLELLSG 559
Query 1097 ------HCDSSQSPPTKFL--ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148
H + L + + G+ +L E ++ P + + L
Sbjct 560 REAVTIHKKKEGEEEVEMLCKVINSVLGGENVREKLKEFMDPSLGNEYPLELAYTMAQLA 619
Query 1149 KNCWETEASFRPTFENLIPILKTV 1172
K+C T+ + RP+ ++ L +
Sbjct 620 KSCVATDLNSRPSVTQVLTTLSMI 643
Score = 57.8 bits (138), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 47/167 (28%), Positives = 82/167 (49%), Gaps = 24/167 (14%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK--MVVAQQ 717
+L+ +++H+++ + G C+R + +V EY E+G + WL G + WK + +A+
Sbjct 407 NLLKKLNHSNIIRLSGFCIREGTSYLVFEYSENGSISDWL-HSSGKKSLTWKQRVEIARD 465
Query 718 LASALSYLENKNL---VHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPGVGLGA 766
+A AL YL N +H N+ NILL A G+A ++ D G
Sbjct 466 VAEALDYLHNYITPPHIHKNLESTNILLDSNFRAKIANFGVA-------RILDEGDLDLQ 518
Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
L+R + +LAPE + G +++ +D + FG +LE+ EA
Sbjct 519 LTRHVEGTQ-GYLAPEYVENGV--ITSKLDVFAFGVAVLELLSGREA 562
>sp|Q9SZD5|LRK59_ARATH L-type lectin-domain containing receptor
kinase V.9 OS=Arabidopsis thaliana OX=3702 GN=LECRK59 PE=2
SV=1
Length=669
Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 68/199 (34%), Positives = 99/199 (50%), Gaps = 17/199 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FGKV Y T + +AVK + D R + EI + L H ++++
Sbjct 350 LGKGGFGKV----YKGTLSTSNMDIAVKKVSHDSRQGMRE-FVAEIATIGRLRHPNLVRL 404
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH---A 1016
G C +GE L LV + +P GSL +L P S+ +Q + + G+ YLH
Sbjct 405 LGYCRRKGE--LYLVYDCMPKGSLDKFLYHQPEQSLDWSQRFKIIKDVASGLCYLHHQWV 462
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075
Q IHRD+ NVLLD+ K+GDFGLAK G + G F Y +PE +
Sbjct 463 QVIIHRDIKPANVLLDDSMNGKLGDFGLAKLCEHGFDPQTSNVAG---TFGYISPELSRT 519
Query 1076 YKFYYASDVWSFGVTLYEL 1094
K +SDV++FG+ + E+
Sbjct 520 GKASTSSDVFAFGILMLEI 538
>sp|Q54MY9|MKCA_DICDI Probable serine/threonine-protein kinase
mkcA OS=Dictyostelium discoideum OX=44689 GN=mkcA PE=2 SV=1
Length=860
Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 73/290 (25%), Positives = 129/290 (44%), Gaps = 35/290 (12%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
D PT K+ +G+G FG V Y D + +A+K L P R
Sbjct 571 DQICKKPTNEMKKLYTFREKVGKGGFGTV--YLVRNNMDKSKSRIAIKKL-----PHVRK 623
Query 943 GWKQ----EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA 998
K+ EI +L H +II Y E + + ME++ G+L + ++ +
Sbjct 624 KEKKFNVKEIRVLEFTNHPNIITYYNSHMLHDE--VWIAMEFMEGGTLAEASNQYPFQES 681
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
+ A+++ +G+AYLH +HRDL ++N+++ +K+ DFGL + +G R+R
Sbjct 682 NIAYVAREVLQGLAYLHGIQLVHRDLKSQNIMMTTSGEIKLIDFGLCANLSKGE---RIR 738
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
G SP+ W PE +++ + Y D+WS + L EL + + P K + ++G
Sbjct 739 MCG-SPI-WMPPEMIQQKQHGYTCDIWSTAICLLELANRNNKLRKNPIKTMFMVG----- 791
Query 1119 MTVLRLTELLERGERLP--RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
G + P P K E + ++ C + + RP+ + L+
Sbjct 792 ----------SEGIKDPFEDPHKWSDEFHDIINKCLQMDPHKRPSAQELL 831
Score = 38.5 bits (88), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 22/160 (14%)
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
VA+++ L+YL LVH ++ +NI++ TS IKL D G+ LS+ ER+
Sbjct 686 VAREVLQGLAYLHGIQLVHRDLKSQNIMMT-------TSGEIKLIDFGL-CANLSKGERI 737
Query 774 ERI---PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
W+ PE + + + D W LLE+ + R K F
Sbjct 738 RMCGSPIWMPPEMIQQKQHGYTC--DIWSTAICLLELANRNN---KLRKNPIKTMFMVGS 792
Query 831 HRLPEPS------CPQLATLTSQCLTYEPTQRPSFRTILR 864
+ +P + + ++CL +P +RPS + +L+
Sbjct 793 EGIKDPFEDPHKWSDEFHDIINKCLQMDPHKRPSAQELLK 832
>sp|Q6IP06|STK3_XENLA Serine/threonine-protein kinase 3 OS=Xenopus
laevis OX=8355 GN=stk3 PE=2 SV=1
Length=493
Score = 87.4 bits (215), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 56/197 (28%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V + + +G++VA+K + + Q +EI I++ ++
Sbjct 29 LEKLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQE---IIKEISIMQQCDSHYV 81
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ + +G+ YLH
Sbjct 82 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILRSTLKGLEYLHFM 139
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 140 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVIQEIG 196
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 197 YNCVADIWSLGITSIEM 213
>sp|Q9SCZ4|FERON_ARATH Receptor-like protein kinase FERONIA OS=Arabidopsis
thaliana OX=3702 GN=FER PE=1 SV=1
Length=895
Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 77/227 (34%), Positives = 109/227 (48%), Gaps = 26/227 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHE 957
R LG G FGKV Y DG VA+K P G ++ EI++L L H
Sbjct 540 RVLGVGGFGKV----YRGEIDGGTTKVAIKR----GNPMSEQGVHEFQTEIEMLSKLRHR 591
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYL 1014
H++ G CE+ E + LV +Y+ G++R++L + S+ Q L G+ YL
Sbjct 592 HLVSLIGYCEENCE--MILVYDYMAHGTMREHLYKTQNPSLPWKQRLEICIGAARGLHYL 649
Query 1015 H--AQH-YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWY-A 1069
H A+H IHRD+ N+LLD + K+ DFGL+K P H + G F Y
Sbjct 650 HTGAKHTIIHRDVKTTNILLDEKWVAKVSDFGLSKTGPTLDHTHVSTVVKGS---FGYLD 706
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
PE + + SDV+SFGV L+E L C PT E + +A+
Sbjct 707 PEYFRRQQLTEKSDVYSFGVVLFEAL--CARPALNPTLAKEQVSLAE 751
Score = 41.2 bits (95), Expect = 0.073, Method: Compositional matrix adjust.
Identities = 47/182 (26%), Positives = 74/182 (41%), Gaps = 9/182 (5%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G G +V +K +P F ++S++ H HL + G C E I+V +Y
Sbjct 553 GEIDGGTTKVAIKRGNPMSEQGVHEFQTEIEMLSKLRHRHLVSLIGYCEENCEMILVYDY 612
Query 690 VEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARL 745
+ HG + L + + +P ++ + A L YL ++H +V NILL
Sbjct 613 MAHGTMREHLYKTQNPSLPWKQRLEICIGAARGLHYLHTGAKHTIIHRDVKTTNILLDEK 672
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+A+ S F LS G L V+ +L PE L+ D + FG L
Sbjct 673 WVAK-VSDF-GLSKTGPTLDHTHVSTVVKGSFGYLDPEYFR--RQQLTEKSDVYSFGVVL 728
Query 805 LE 806
E
Sbjct 729 FE 730
>sp|Q55GV3|PAKC_DICDI Serine/threonine-protein kinase pakC OS=Dictyostelium
discoideum OX=44689 GN=pakC PE=1 SV=2
Length=477
Score = 87.0 bits (214), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 63/239 (26%), Positives = 116/239 (49%), Gaps = 22/239 (9%)
Query 864 RDLTRLQPHNLADV-----LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918
R + + NL+ + LT++ DPT +K K +GEG G+V +
Sbjct 170 RTMEKSNSQNLSALPDESNLTLSDLVTKEDPTKIYKNMTK----IGEGAAGEV----FVA 221
Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978
T+ + VA+K K + + EI I++T +H++I+ Y ++ L + M
Sbjct 222 TSSKNNKRVAIK--KIEINNDNAKLLVTEIAIMKTSHHDNIVNYIDSY-IVNDRELWVAM 278
Query 979 EYVPLGSLRDYLPR-HSIGLA--QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035
E++ G L D L +I ++ Q+ ++ + + Y+H+ H IHRD+ + N+LL ++
Sbjct 279 EFMGGGCLTDILEAFDNIKMSEIQIAYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEG 338
Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
VKI DFG A + + + R +W APE ++ + + D+WS G+ + E+
Sbjct 339 SVKIADFGYAAQLTQKQQK---RNTVVGTPYWMAPELIRGHDYGVKVDIWSLGIMMMEM 394
Score = 43.9 bits (102), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 61/331 (18%), Positives = 135/331 (41%), Gaps = 40/331 (12%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRT--LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605
++ L +P E +++ + R ++ NLS L D+ +T + + T +Y+
Sbjct 150 KQEVLDKPSEWLSVLEFQAGRTMEKSNSQNLSALP----DESNLTLSDLVTKEDPTKIYK 205
Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV 665
++ G+ G++ V + + RV +K ++ ++ + L E A + +
Sbjct 206 NMTKI---GEGAAGEV-----FVATSSKNNK-RVAIKKIEINNDNAKLLVTEIAIMKTSH 256
Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHG----PLDVWLRRERGHVPMAWKMVVAQQLASA 721
+ ++ V E + E++ G L+ + + + +A+ V ++ A
Sbjct 257 HDNIVNYIDSYIVNDRELWVAMEFMGGGCLTDILEAFDNIKMSEIQIAY---VVKETLKA 313
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---- 777
L Y+ + + +H ++ NILL +EG+ +K++D G ++++ +
Sbjct 314 LQYIHSLHRIHRDIKSDNILLG----SEGS---VKIADFGYAAQLTQKQQKRNTVVGTPY 366
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS 837
W+APE + G + +D W G ++E+ +GE P P + P
Sbjct 367 WMAPELIRG--HDYGVKVDIWSLGIMMMEMA-EGEPPYMDFPPLRALFLITTKGIPPLKE 423
Query 838 CPQLAT----LTSQCLTYEPTQRPSFRTILR 864
+ + S+CL RP +L+
Sbjct 424 TTKWSKTFQDFFSKCLDINVANRPDATDLLK 454
>sp|Q8H1G6|PTI11_ARATH PTI1-like tyrosine-protein kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=PTI11 PE=1 SV=1
Length=361
Score = 85.9 bits (211), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 80/285 (28%), Positives = 127/285 (45%), Gaps = 28/285 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG--WKQEIDILRTLYHEHII 960
+GEG +G+V Y NDG VAV K D P+ + + ++ ++ L HE++I
Sbjct 74 IGEGSYGRVY---YATLNDG----VAVALKKLDVAPEAETDTEFLSQVSMVSRLKHENLI 126
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQLLLFAQQICEG 1010
+ G C D + L E+ +GSL D L P ++ + A + G
Sbjct 127 QLLGFCVDGNLRVL--AYEFATMGSLHDILHGRKGVQGAQPGPTLDWITRVKIAVEAARG 184
Query 1011 MAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH + IHRD+ + NVLL D KI DF L+ P+ R+ F
Sbjct 185 LEYLHEKSQPPVIHRDIRSSNVLLFEDYKAKIADFNLSNQAPDNAA--RLHSTRVLGTFG 242
Query 1068 Y-APECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
Y APE + SDV+SFGV L ELLT + P L+ A +++ ++
Sbjct 243 YHAPEYAMTGQLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRLSEDKVK 302
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ ++ + P K ++ + C + EA FRP ++ L+
Sbjct 303 QCIDPKLKADYPPKAVAKLAAVAALCVQYEAEFRPNMSIVVKALQ 347
Score = 40.4 bits (93), Expect = 0.081, Method: Compositional matrix adjust.
Identities = 65/262 (25%), Positives = 106/262 (40%), Gaps = 36/262 (14%)
Query 639 VVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-D 696
V LK LD + + F S++S++ H +L + G CV G ++ E+ G L D
Sbjct 93 VALKKLDVAPEAETDTEFLSQVSMVSRLKHENLIQLLGFCVDGNLRVLAYEFATMGSLHD 152
Query 697 VWLRRE--RGHVP---MAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLG 746
+ R+ +G P + W ++ +A + A L YL K+ ++H ++ N+LL
Sbjct 153 ILHGRKGVQGAQPGPTLDWITRVKIAVEAARGLEYLHEKSQPPVIHRDIRSSNVLLFEDY 212
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
A+ LS+ A RV + APE G L+ D + FG LL
Sbjct 213 KAKIAD--FNLSNQAPDNAARLHSTRVLGTFGYHAPEYAMTG--QLTQKSDVYSFGVVLL 268
Query 806 EICFDGEAPLQSRSPSEKEHFYQ-RQHRLPEPSCPQ-----------------LATLTSQ 847
E+ G P+ P ++ RL E Q LA + +
Sbjct 269 EL-LTGRKPVDHTMPRGQQSLVTWATPRLSEDKVKQCIDPKLKADYPPKAVAKLAAVAAL 327
Query 848 CLTYEPTQRPSFRTILRDLTRL 869
C+ YE RP+ +++ L L
Sbjct 328 CVQYEAEFRPNMSIVVKALQPL 349
>sp|Q60806|PLK3_MOUSE Serine/threonine-protein kinase PLK3 OS=Mus
musculus OX=10090 GN=Plk3 PE=1 SV=2
Length=631
Score = 87.8 bits (216), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 67/220 (30%), Positives = 105/220 (48%), Gaps = 17/220 (8%)
Query 882 PDSPA---SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--C 936
PD P +DP R K R LG+G F + CY+ T+ +G AVK +
Sbjct 47 PDPPGRLITDP--LSGRTYTKGRLLGKGGFAR----CYEATDTESGIAYAVKVIPQSRVA 100
Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSI 995
P R EI++ R L H HI+++ ED ++ + +E SL + RH++
Sbjct 101 KPHQREKILNEIELHRDLQHRHIVRFSHHFEDA--DNIYIFLELCSRKSLAHIWKARHTL 158
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
++ + +QI G+ YLH + +HRDL N + ++ +K+GDFGLA + +
Sbjct 159 LEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQ-- 216
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
R + +P + APE L +DVWS G +Y LL
Sbjct 217 RKKTICGTPNY-VAPEVLLRQGHGPEADVWSLGCVMYTLL 255
>sp|O49339|PTI12_ARATH PTI1-like tyrosine-protein kinase 2 OS=Arabidopsis
thaliana OX=3702 GN=PTI12 PE=1 SV=1
Length=366
Score = 85.9 bits (211), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 76/283 (27%), Positives = 127/283 (45%), Gaps = 24/283 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG +G+V Y NDG VA+K L + + + ++ ++ L HE++I+
Sbjct 77 IGEGSYGRV---YYATLNDGKA--VALKKLDVAPEAETNTEFLNQVSMVSRLKHENLIQL 131
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQLLLFAQQICEGMA 1012
G C D+ + L E+ +GSL D L P ++ + A + G+
Sbjct 132 VGYCVDENLRVL--AYEFATMGSLHDILHGRKGVQGAQPGPTLDWLTRVKIAVEAARGLE 189
Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068
YLH + IHRD+ + NVLL D K+ DF L+ P+ R+ F Y
Sbjct 190 YLHEKVQPPVIHRDIRSSNVLLFEDYQAKVADFNLSNQAPDNAA--RLHSTRVLGTFGYH 247
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + SDV+SFGV L ELLT + P L+ A +++ ++ +
Sbjct 248 APEYAMTGQLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRLSEDKVKQC 307
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
++ + P K ++ + C + E+ FRP ++ L+
Sbjct 308 VDPKLKGEYPPKSVAKLAAVAALCVQYESEFRPNMSIVVKALQ 350
Score = 37.0 bits (84), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 62/262 (24%), Positives = 105/262 (40%), Gaps = 36/262 (14%)
Query 639 VVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-D 696
V LK LD + + F S++S++ H +L + G CV ++ E+ G L D
Sbjct 96 VALKKLDVAPEAETNTEFLNQVSMVSRLKHENLIQLVGYCVDENLRVLAYEFATMGSLHD 155
Query 697 VWLRRE--RGHVP---MAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLG 746
+ R+ +G P + W ++ +A + A L YL K ++H ++ N+LL
Sbjct 156 ILHGRKGVQGAQPGPTLDWLTRVKIAVEAARGLEYLHEKVQPPVIHRDIRSSNVLLFEDY 215
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
A+ LS+ A RV + APE G L+ D + FG LL
Sbjct 216 QAKVAD--FNLSNQAPDNAARLHSTRVLGTFGYHAPEYAMTG--QLTQKSDVYSFGVVLL 271
Query 806 EICFDGEAPLQSRSPSEKEHFY------------------QRQHRLPEPSCPQLATLTSQ 847
E+ G P+ P ++ + + P S +LA + +
Sbjct 272 EL-LTGRKPVDHTMPRGQQSLVTWATPRLSEDKVKQCVDPKLKGEYPPKSVAKLAAVAAL 330
Query 848 CLTYEPTQRPSFRTILRDLTRL 869
C+ YE RP+ +++ L L
Sbjct 331 CVQYESEFRPNMSIVVKALQPL 352
>sp|Q751E8|PHO85_EREGS Negative regulator of the PHO system OS=Eremothecium
gossypii (strain ATCC 10895 / CBS 109.51 / FGSC
9923 / NRRL Y-1056) OX=284811 GN=PHO85 PE=3 SV=2
Length=301
Score = 84.7 bits (208), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 63/209 (30%), Positives = 102/209 (49%), Gaps = 22/209 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
K++ LG G + V Y N TG VA+K +K D S +EI +++ L H
Sbjct 7 FKQLERLGNGTYATV----YKGLNKTTGLYVALKEVKLDSEEGTPSTAIREISLMKELKH 62
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--------PRHSIGLAQLLLFAQQIC 1008
E+I++ E L LV E++ L+ ++ PR + L+ + F Q+
Sbjct 63 ENIVRLYDVI--HTENKLTLVFEFMD-NDLKKFMDSRLDREMPR-GLELSLVKYFQWQLL 118
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+G+A+ H +HRDL +N+L++N +K+GDFGLA+A + + WY
Sbjct 119 QGVAFCHENRILHRDLKPQNLLINNKGQLKLGDFGLARAFGIPVNTF----SSEVVTLWY 174
Query 1069 -APECLKEYKFYYAS-DVWSFGVTLYELL 1095
AP+ L + Y S D+WS G L E++
Sbjct 175 RAPDVLMGSRTYCTSIDIWSCGCILAEMI 203
>sp|Q9FM85|PBL16_ARATH Probable serine/threonine-protein kinase
PBL16 OS=Arabidopsis thaliana OX=3702 GN=PBL16 PE=1 SV=1
Length=408
Score = 86.3 bits (212), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 89/272 (33%), Positives = 124/272 (46%), Gaps = 25/272 (9%)
Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI-------RDLGEGHFGKVSLYC 915
++++ +L P N +V + DS A+ F LK I R LG G FG V
Sbjct 36 IKEVQKL-PSNPKEVEDLRRDSAANPLIAFTYEELKNITSNFRQDRVLGGGGFGSV-YKG 93
Query 916 YDPTNDGTGEM-----VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG-CCEDQ 969
+ + G E+ VAVK D Q W E+ L L H +++K G CCED
Sbjct 94 FIKEDLGDQEVPEPLPVAVKVHDGDNSFQGHREWLAEVIFLGQLSHPNLVKLIGYCCEDN 153
Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSI---GLAQLLLFAQQICEGMAYLH--AQHYIHRDL 1024
L+ EY+ GS+ + L + A + A +G+A+LH + I+RD
Sbjct 154 HR---VLIYEYMARGSVENNLFSRVLLPLSWAIRMKIAFGAAKGLAFLHEAKKPVIYRDF 210
Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084
N+LLD D K+ DFGLAK P G + + V + APE + SDV
Sbjct 211 KTSNILLDMDYNAKLSDFGLAKDGPVGDKSH-VSTRIMGTYGYAAPEYIMTGHLTPGSDV 269
Query 1085 WSFGVTLYELLTHCDS-SQSPPTKFLELIGIA 1115
+SFGV L ELLT S +S PT+ LI A
Sbjct 270 YSFGVVLLELLTGRKSLDKSRPTREQNLIDWA 301
Score = 50.4 bits (119), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 66/268 (25%), Positives = 110/268 (41%), Gaps = 31/268 (12%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQL 718
+ Q+SH +L + G C +++ EY+ G ++ L R +P++W +M +A
Sbjct 133 FLGQLSHPNLVKLIGYCCEDNHRVLIYEYMARGSVENNL-FSRVLLPLSWAIRMKIAFGA 191
Query 719 ASALSYLE--NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI 776
A L++L K +++ + NILL + S F D VG + +
Sbjct 192 AKGLAFLHEAKKPVIYRDFKTSNILL-DMDYNAKLSDFGLAKDGPVGDKSHVSTRIMGTY 250
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--------Q 828
+ APE + G L+ D + FG LLE+ G L P+ +++ +
Sbjct 251 GYAAPEYIMTG--HLTPGSDVYSFGVVLLEL-LTGRKSLDKSRPTREQNLIDWALPLLKE 307
Query 829 RQHRL----PEPSCP-------QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
++ L P+ +C + A L CL P RP R I+ L LQ +
Sbjct 308 KKKVLNIVDPKMNCEYPVKAVQKAAMLAYHCLNRNPKARPLMRDIVDSLEPLQATE-EEA 366
Query 878 LTVNPDSPASDPTV--FHKRYLKKIRDL 903
L V P A + K LKK+ +L
Sbjct 367 LLVPPVQKAVITIIDEMPKNGLKKVEEL 394
>sp|Q5AG71|HSL1_CANAL Serine/threonine-protein kinase HSL1 OS=Candida
albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=HSL1
PE=1 SV=2
Length=1462
Score = 88.6 bits (218), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 67/214 (31%), Positives = 109/214 (51%), Gaps = 29/214 (14%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-----KADCGPQHRS----------GWK 945
R LG G G+V L N TG++ AVK + K P+++ G +
Sbjct 69 RTLGRGSTGRVRL----AKNTTTGQLAAVKIVPKSNFKKLENPKYKRSKEDATRLPYGIE 124
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFA 1004
+EI I++ + H +I+ E++ + L L++EY+ G L DYL R + + + +
Sbjct 125 REIIIMKLISHPNIMGLYDVWENKND--LYLILEYIEGGELFDYLIKRGKLQEYEAINYF 182
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK-AVPEGHEYYRVREDGDS 1063
+QI G+ YLH + HRDL N+LLD ++ +KI DFG+A V E ++ E
Sbjct 183 KQIINGINYLHQFNICHRDLKPENLLLDFNKNIKIADFGMAALEVKE-----KLLETSCG 237
Query 1064 PVFWYAPECLKEYKFYYA-SDVWSFGVTLYELLT 1096
+ +PE + ++ A SD+WS G+ L+ LLT
Sbjct 238 SPHYASPEIVAGKNYHGAPSDIWSCGIILFALLT 271
Score = 36.2 bits (82), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 38/162 (23%), Positives = 72/162 (44%), Gaps = 21/162 (13%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
+M +SH ++ ++ V + ++ EY+E G L +L + RG + + +Q+ +
Sbjct 129 IMKLISHPNIMGLYDVWENKNDLYLILEYIEGGELFDYLIK-RGKLQEYEAINYFKQIIN 187
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP--- 777
++YL N+ H ++ N+LL + IK++D G+ AL +E++
Sbjct 188 GINYLHQFNICHRDLKPENLLL-------DFNKNIKIAD--FGMAALEVKEKLLETSCGS 238
Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGE 812
+ +PE + G N D W G L + FD E
Sbjct 239 PHYASPEIV-AGKNYHGAPSDIWSCGIILFALLTGHLPFDDE 279
>sp|Q07832|PLK1_MOUSE Serine/threonine-protein kinase PLK1 OS=Mus
musculus OX=10090 GN=Plk1 PE=1 SV=2
Length=603
Score = 87.4 bits (215), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 76/269 (28%), Positives = 119/269 (44%), Gaps = 28/269 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEH 958
R LG+G F K C++ ++ T E+ A K + P + EI I R+L H+H
Sbjct 57 RFLGKGGFAK----CFEISDADTKEVFAGKIVPKSLLLKPHQKEKMSMEISIHRSLAHQH 112
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
++ + ED + +V+E SL + + R ++ + + +QI G YLH
Sbjct 113 VVGFHDFFEDSD--FVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRN 170
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRDL N+ L+ D VKIGDFGLA V +E R + +P + APE L +
Sbjct 171 QVIHRDLKLGNLFLNEDLEVKIGDFGLATKVE--YEGERKKTLCGTPN-YIAPEVLSKKG 227
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ DVWS G +Y L L+G + + L+ T L + P
Sbjct 228 HSFEVDVWSIGCIMYTL----------------LVGKPPFETSCLKETYLRIKKNEYSIP 271
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L++ +T+ + RPT L+
Sbjct 272 KHINPVAASLIQKMLQTDPTARPTIHELL 300
Score = 41.6 bits (96), Expect = 0.055, Method: Compositional matrix adjust.
Identities = 36/155 (23%), Positives = 66/155 (43%), Gaps = 15/155 (10%)
Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER 775
+Q+ YL ++H R++ L L L E +K+ D G+ ER +
Sbjct 158 RQIVLGCQYLHRNQVIH-----RDLKLGNLFLNEDLE--VKIGDFGLATKVEYEGERKKT 210
Query 776 I----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQ 830
+ ++APE L +S +D W G + + G+ P ++ E + +
Sbjct 211 LCGTPNYIAPEVLSKKGHSFE--VDVWSIGCIMYTLLV-GKPPFETSCLKETYLRIKKNE 267
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ +P+ P A+L + L +PT RP+ +L D
Sbjct 268 YSIPKHINPVAASLIQKMLQTDPTARPTIHELLND 302
>sp|P51958|CDK1_CARAU Cyclin-dependent kinase 1 OS=Carassius auratus
OX=7957 GN=cdk1 PE=1 SV=1
Length=302
Score = 84.7 bits (208), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 70/235 (30%), Positives = 110/235 (47%), Gaps = 27/235 (11%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957
KI +GEG +G V Y N TG++VA+K ++ + + S +EI +L+ L H
Sbjct 6 KIEKIGEGTYGVV----YKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHP 61
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL------LFAQQICEGM 1011
++++ E L LV E++ + L+ YL SI Q + + QI EG+
Sbjct 62 NVVRLLDVL--MQESKLYLVFEFLSM-DLKKYL--DSIPSGQFMDPMLVKSYLYQILEGI 116
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-AP 1070
+ H + +HRDL +N+L+DN ++K+ DFGLA+A Y + WY AP
Sbjct 117 LFCHCRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVPVRVYT----HEVVTLWYRAP 172
Query 1071 EC-LKEYKFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQM 1119
E L ++ DVWS G EL T H DS + +G ++
Sbjct 173 EVLLGASRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNEV 227
>sp|Q9M9E0|LRKS1_ARATH L-type lectin-domain containing receptor
kinase S.1 OS=Arabidopsis thaliana OX=3702 GN=LECRKS1 PE=1
SV=1
Length=656
Score = 87.8 bits (216), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 67/202 (33%), Positives = 101/202 (50%), Gaps = 16/202 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LG G FGKV Y E +AVK + D R + EI + L H++++
Sbjct 365 RLLGSGGFGKV----YRGILSNNSE-IAVKCVNHDSKQGLRE-FMAEISSMGRLQHKNLV 418
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH-- 1015
+ +G C + E L LV +Y+P GSL ++ P+ + + + EG+ YLH
Sbjct 419 QMRGWCRRKNE--LMLVYDYMPNGSLNQWIFDNPKEPMPWRRRRQVINDVAEGLNYLHHG 476
Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
Q IHRD+ + N+LLD++ ++GDFGLAK G R G + + APE
Sbjct 477 WDQVVIHRDIKSSNILLDSEMRGRLGDFGLAKLYEHGGAPNTTRVVG--TLGYLAPELAS 534
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
ASDV+SFGV + E+++
Sbjct 535 ASAPTEASDVYSFGVVVLEVVS 556
Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 47/168 (28%), Positives = 82/168 (49%), Gaps = 13/168 (8%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F S M ++ H +L + G C R E ++V +Y+ +G L+ W+ + PM W +
Sbjct 402 FMAEISSMGRLQHKNLVQMRGWCRRKNELMLVYDYMPNGSLNQWI-FDNPKEPMPWRRRR 460
Query 713 VVAQQLASALSYLE---NKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALS 768
V +A L+YL ++ ++H ++ NILL + + G KL + G GA +
Sbjct 461 QVINDVAEGLNYLHHGWDQVVIHRDIKSSNILLDSEMRGRLGDFGLAKLYEHG---GAPN 517
Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
V + +LAPE A++ + A D + FG +LE+ G P++
Sbjct 518 TTRVVGTLGYLAPEL--ASASAPTEASDVYSFGVVVLEVV-SGRRPIE 562
>sp|Q7ZUQ3|STK3_DANRE Serine/threonine-protein kinase 3 OS=Danio
rerio OX=7955 GN=stk3 PE=2 SV=1
Length=492
Score = 87.0 bits (214), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 56/197 (28%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V + + +G++VA+K + + Q +EI I++ ++
Sbjct 29 LEKLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQE---IIKEISIMQQCDSPYV 81
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D L ++ ++ + +G+ YLH
Sbjct 82 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLKSTLKGLEYLHFM 139
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 140 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 196
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 197 YNCVADIWSLGITSIEM 213
>sp|C0LGW2|PAM74_ARATH Probable LRR receptor-like serine/threonine-protein
kinase PAM74 OS=Arabidopsis thaliana OX=3702 GN=PAM74
PE=1 SV=1
Length=884
Score = 88.2 bits (217), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 57/181 (31%), Positives = 93/181 (51%), Gaps = 11/181 (6%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
E VAVK L + Q +K E+D+L ++H +++ G C+++ L L+ E++P
Sbjct 601 SEQVAVKVL-SQSSSQGYKHFKAEVDLLLRVHHTNLVSLVGYCDERDH--LALIYEFLPK 657
Query 984 GSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRL 1036
G LR +L S I L A + G+ YLH+ +HRD+ N+LLD
Sbjct 658 GDLRQHLSGKSGGSFINWGNRLRIALEAALGLEYLHSGCTPPIVHRDIKTTNILLDEQLK 717
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
K+ DFGL+++ P G E + +P + PE + + SDV+SFG+ L E++T
Sbjct 718 AKLADFGLSRSFPIGGETHISTVVAGTPGY-LDPEYYQTTRLGEKSDVYSFGIVLLEIIT 776
Query 1097 H 1097
+
Sbjct 777 N 777
Score = 40.8 bits (94), Expect = 0.085, Method: Compositional matrix adjust.
Identities = 57/203 (28%), Positives = 82/203 (40%), Gaps = 21/203 (10%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G G E +V +KVL S F L+ +V HT+L + G C ++ E+
Sbjct 596 GTINGSE-QVAVKVLSQSSSQGYKHFKAEVDLLLRVHHTNLVSLVGYCDERDHLALIYEF 654
Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744
+ G L L + G + W ++ +A + A L YL + +VH ++ NILL
Sbjct 655 LPKGDLRQHLSGKSGGSFINWGNRLRIALEAALGLEYLHSGCTPPIVHRDIKTTNILLDE 714
Query 745 LGLAEGTSPFIKLSDPGVGL-----GALSREERVERIP-WLAPECLPGGANSLSTAMDKW 798
A KL+D G+ G V P +L PE L D +
Sbjct 715 QLKA-------KLADFGLSRSFPIGGETHISTVVAGTPGYLDPEYYQ--TTRLGEKSDVY 765
Query 799 GFGATLLEICFDGEAPLQSRSPS 821
FG LLEI + QSRS S
Sbjct 766 SFGIVLLEIITNQPVIDQSRSKS 788
>sp|Q54EY4|DST3_DICDI Serine/threonine-protein kinase dst3 OS=Dictyostelium
discoideum OX=44689 GN=dst3 PE=3 SV=1
Length=562
Score = 87.0 bits (214), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 61/200 (31%), Positives = 101/200 (51%), Gaps = 15/200 (8%)
Query 903 LGEGHFGKVS----LYCYDPTNDGTGEMVAVKALKADCGPQHRS-GWKQEIDILR-TLYH 956
+G G FG V + D ++G ++A K ++ + + +EIDIL+ ++
Sbjct 29 VGSGSFGTVCACRWMKKKDRESNG-NRLIACKFVEVNADDVETNLNLVKEIDILKESMDC 87
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYL 1014
+I++YKGC L +VMEY GSL D + L + + + +G+ YL
Sbjct 88 PYIVEYKGCYLKSS--MLLIVMEYCKGGSLLDIIELCGKRLIEEEIAAVCAGVVKGLVYL 145
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H++ HRD+ A NVLLD + L K+ DFG++ +G + V SP +W APE +
Sbjct 146 HSKRTTHRDIKAGNVLLDEEGLPKLADFGVSTIAEQGQKMNTVI---GSP-YWMAPEIIM 201
Query 1075 EYKFYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 202 GQGYDQKADIWSLGITAIEI 221
Score = 43.5 bits (101), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 52/197 (26%), Positives = 80/197 (41%), Gaps = 37/197 (19%)
Query 684 IMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLASA-------LSYLENKNLVHGNV 735
++V EY + G L D+ + + K ++ +++A+ L YL +K H ++
Sbjct 104 LIVMEYCKGGSLLDI--------IELCGKRLIEEEIAAVCAGVVKGLVYLHSKRTTHRDI 155
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---WLAPECLPGGANSLS 792
N+LL GL KL+D GV A ++ I W+APE + G
Sbjct 156 KAGNVLLDEEGLP-------KLADFGVSTIAEQGQKMNTVIGSPYWMAPEIIMGQG--YD 206
Query 793 TAMDKWGFGATLLEIC------FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTS 846
D W G T +EI FD P SR H ++P P+
Sbjct 207 QKADIWSLGITAIEIAELVPPRFD--VP-PSRVIFTIPHQPPPSLKIPSDWSPEFNDFVK 263
Query 847 QCLTYEPTQRPSFRTIL 863
QCL+ P RPS + +L
Sbjct 264 QCLSMNPALRPSAQQLL 280
>sp|Q9LFT8|CDKC1_ARATH Cyclin-dependent kinase C-1 OS=Arabidopsis
thaliana OX=3702 GN=CDKC-1 PE=1 SV=1
Length=505
Score = 87.0 bits (214), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 67/221 (30%), Positives = 105/221 (48%), Gaps = 33/221 (15%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILR 952
+K+ +GEG +G+V Y TGE+VA+K ++ D R G+ +EI IL+
Sbjct 26 FEKLEQIGEGTYGQV----YMAKEIKTGEIVALKKIRMD---NEREGFPITAIREIKILK 78
Query 953 TLYHEHIIKYKGCC-------EDQGEKS-------LQLVMEYVP--LGSLRDYLPRHSIG 996
L+HE++I+ K +DQG+ + +V EY+ L L D P
Sbjct 79 KLHHENVIQLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLAD-RPGLRFT 137
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
+ Q+ + +Q+ G+ Y H +HRD+ N+L+DN+ +K+ DFGLA++ H
Sbjct 138 VPQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGNL 197
Query 1057 VREDGDSPVFWYAPE--CLKEYKFYYASDVWSFGVTLYELL 1095
WY P L K+ A D+WS G ELL
Sbjct 198 TNR---VITLWYRPPELLLGATKYGPAIDMWSVGCIFAELL 235
>sp|U4PR86|MELK_CAEEL Maternal embryonic leucine zipper kinase
OS=Caenorhabditis elegans OX=6239 GN=pig-1 PE=1 SV=1
Length=706
Score = 87.4 bits (215), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 67/199 (34%), Positives = 101/199 (51%), Gaps = 12/199 (6%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+LG G FGKV L + TN + VA+K + + E+D LR L H++I +
Sbjct 16 ELGSGGFGKVRLATHLLTN----QKVAIKIIDKKQLGHDLPRVQTEMDALRNLSHQNICR 71
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020
E E +VMEY G + DY+ R + ++ F +Q+ +A++H+Q Y
Sbjct 72 LYHYIET--EDKFFIVMEYCSGGEMFDYIVRKERLEESEARHFFRQLVSAIAFVHSQGYA 129
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH-EYYRVREDGDSPVFWYAPECLK--EYK 1077
HRDL N+LL D +K+ DFGL +G + + + SP + APE ++ +YK
Sbjct 130 HRDLKPENLLLTEDLHLKLIDFGLCAKTEKGRIDKHNLDTCCGSPAY-AAPELIQGLQYK 188
Query 1078 FYYASDVWSFGVTLYELLT 1096
A DVWS G+ LY LL
Sbjct 189 GNEA-DVWSMGILLYTLLV 206
>sp|C0LGL4|Y2289_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At2g28960 OS=Arabidopsis thaliana OX=3702
GN=At2g28960 PE=1 SV=1
Length=880
Score = 87.8 bits (216), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 64/203 (32%), Positives = 103/203 (51%), Gaps = 16/203 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LGEG FG V Y +GT + +AVK L + Q +K E+++L ++H +++
Sbjct 577 RVLGEGGFGVV----YHGILNGT-QPIAVKLL-SQSSVQGYKEFKAEVELLLRVHHVNLV 630
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLHA 1016
G C++ E +L L+ EY P G L+ +L G + L + +G+ YLH
Sbjct 631 SLVGYCDE--ESNLALLYEYAPNGDLKQHLSGERGGSPLKWSSRLKIVVETAQGLEYLHT 688
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+HRD+ N+LLD K+ DFGL+++ P G E + +P + PE
Sbjct 689 GCKPPMVHRDVKTTNILLDEHFQAKLADFGLSRSFPVGGETHVSTAVAGTPGYL-DPEYY 747
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
+ + SDV+SFG+ L E++T
Sbjct 748 RTNRLNEKSDVYSFGIVLLEIIT 770
Score = 47.4 bits (111), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 56/199 (28%), Positives = 79/199 (40%), Gaps = 23/199 (12%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+ +K+L S F L+ +V H +L + G C ++ EY +G L
Sbjct 598 IAVKLLSQSSVQGYKEFKAEVELLLRVHHVNLVSLVGYCDEESNLALLYEYAPNGDLKQH 657
Query 699 LRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSP 753
L ERG P+ W ++ + + A L YL +VH +V NILL A
Sbjct 658 LSGERGGSPLKWSSRLKIVVETAQGLEYLHTGCKPPMVHRDVKTTNILLDEHFQA----- 712
Query 754 FIKLSDPGVGL-----GALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
KL+D G+ G V P +L PE N L+ D + FG LLEI
Sbjct 713 --KLADFGLSRSFPVGGETHVSTAVAGTPGYLDPEYY--RTNRLNEKSDVYSFGIVLLEI 768
Query 808 CFDGEAPLQSRSPSEKEHF 826
Q+R EK H
Sbjct 769 ITSRPVIQQTR---EKPHI 784
>sp|Q84SN3|CDKF3_ORYSJ Cyclin-dependent kinase F-3 OS=Oryza sativa
subsp. japonica OX=39947 GN=CDKF-3 PE=2 SV=1
Length=433
Score = 86.3 bits (212), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 71/210 (34%), Positives = 101/210 (48%), Gaps = 24/210 (11%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+RY K IR++G+G G V + N T E+VAVK +K +E+ L+
Sbjct 2 ERY-KVIREIGDGTCGNV----FRAYNTETNEIVAVKKMKRKFFQWEECISLREVKALQK 56
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGM 1011
L H +I+K K + E L + E + +L D + ++ + F QI +G+
Sbjct 57 LNHPNIVKLKEVTMENHE--LFFIFENMEC-NLYDVIRERQAAFSEEEIRNFMVQILQGL 113
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV---PEGHEYYRVREDGDSPVFWY 1068
AY+H Y HRDL N+L+ D VKI DFGLA+ V P +Y R WY
Sbjct 114 AYMHNNGYFHRDLKPENLLV-TDGTVKIADFGLAREVSSSPPYTDYVSTR--------WY 164
Query 1069 -APECLKEYKFYY-ASDVWSFGVTLYELLT 1096
APE L + Y A D+W+ G L EL T
Sbjct 165 RAPEVLLQSSAYTPAIDMWAVGAILAELFT 194
>sp|Q9FIZ3|GSO2_ARATH LRR receptor-like serine/threonine-protein
kinase GSO2 OS=Arabidopsis thaliana OX=3702 GN=GSO2 PE=1
SV=2
Length=1252
Score = 87.8 bits (216), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 65/220 (30%), Positives = 103/220 (47%), Gaps = 16/220 (7%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
D + YL + +G G GKV Y + N GE +AVK + + +E
Sbjct 939 DDIMEATHYLNEEFMIGSGGSGKV--YKAELKN---GETIAVKKILWKDDLMSNKSFNRE 993
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSIGLAQL 1000
+ L T+ H H++K G C + + L+ EY+ GS+ D+L + +G
Sbjct 994 VKTLGTIRHRHLVKLMGYCSSKADGLNLLIYEYMANGSVWDWLHANENTKKKEVLGWETR 1053
Query 1001 LLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
L A + +G+ YLH +HRD+ + NVLLD++ +GDFGLAK + ++
Sbjct 1054 LKIALGLAQGVEYLHYDCVPPIVHRDIKSSNVLLDSNIEAHLGDFGLAKILTGNYDTNTE 1113
Query 1058 REDGDSPVFWY-APECLKEYKFYYASDVWSFGVTLYELLT 1096
+ + Y APE K SDV+S G+ L E++T
Sbjct 1114 SNTMFAGSYGYIAPEYAYSLKATEKSDVYSMGIVLMEIVT 1153
>sp|Q13188|STK3_HUMAN Serine/threonine-protein kinase 3 OS=Homo
sapiens OX=9606 GN=STK3 PE=1 SV=2
Length=491
Score = 86.7 bits (213), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 56/197 (28%), Positives = 97/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V + + +G++VA+K + + Q +EI I++ ++
Sbjct 30 LEKLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQE---IIKEISIMQQCDSPYV 82
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQ 1017
+KY G + L +VMEY GS+ D + + L + + + +G+ YLH
Sbjct 83 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFM 140
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E
Sbjct 141 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVIQEIG 197
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+WS G+T E+
Sbjct 198 YNCVADIWSLGITSIEM 214
>sp|P83104|M3K7L_DROME Putative mitogen-activated protein kinase
kinase kinase 7-like OS=Drosophila melanogaster OX=7227 GN=Takl1
PE=2 SV=1
Length=393
Score = 85.5 bits (210), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 76/254 (30%), Positives = 125/254 (49%), Gaps = 33/254 (13%)
Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGL 997
+ ++EI L + HE++I+ G + G+K L+MEY+ GSL +YL + +
Sbjct 48 KKNAEREITHLSEIDHENVIRVIGRASN-GKKDY-LLMEYLEEGSLHNYLYGDDKWEYTV 105
Query 998 AQLLLFAQQICEGMAYLHA--QHYIHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEY 1054
Q + +A Q + +AYLH+ + +HRD+ +N+LL N +KI DFGLA +
Sbjct 106 EQAVRWALQCAKALAYLHSLDRPIVHRDIKPQNMLLYNQHEDLKICDFGLATDMSNN--- 162
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ D + + APE +K K+ DV+SFG+ L+EL+T + P LE
Sbjct 163 ---KTDMQGTLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMT-----RQLPYSHLE---N 211
Query 1115 AQGQMTVLRLTELLERGERLP----RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
Q +++ + GE+LP R D CP + LM+ C + RP+ + I K
Sbjct 212 PNSQYAIMK---AISSGEKLPMEAVRSD-CPEGIKQLMECCMDINPEKRPSMKE---IEK 264
Query 1171 TVHEKYQGQAPSVF 1184
+ E+Y+ F
Sbjct 265 FLGEQYESGTDEDF 278
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 52/245 (21%), Positives = 101/245 (41%), Gaps = 30/245 (12%)
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
Q + +K+ D I + +S++ H ++ V G G ++ ++ EY+E G
Sbjct 31 QNQEIAVKIFDFLEETIKKNAEREITHLSEIDHENVIRVIGRASNGKKDYLLMEYLEEGS 90
Query 695 LDVWLRRERGHVPMAWKMVVAQ------QLASALSYLE--NKNLVHGNVCGRNILLARLG 746
L +L + W+ V Q Q A AL+YL ++ +VH ++ +N+LL
Sbjct 91 LHNYL-----YGDDKWEYTVEQAVRWALQCAKALAYLHSLDRPIVHRDIKPQNMLLY--- 142
Query 747 LAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+K+ D G+ + + ++ + ++APE + + D + FG L
Sbjct 143 ---NQHEDLKICDFGLATDMSNNKTDMQGTLRYMAPEAIKHL--KYTAKCDVYSFGIMLW 197
Query 806 EICFDGEAPLQSRSPSEKEHFYQ---RQHRLP----EPSCPQ-LATLTSQCLTYEPTQRP 857
E+ +P+ + + +LP CP+ + L C+ P +RP
Sbjct 198 ELMTRQLPYSHLENPNSQYAIMKAISSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRP 257
Query 858 SFRTI 862
S + I
Sbjct 258 SMKEI 262
>sp|Q90XC2|NEK8_DANRE Serine/threonine-protein kinase Nek8 OS=Danio
rerio OX=7955 GN=nek8 PE=2 SV=1
Length=697
Score = 87.4 bits (215), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 77/277 (28%), Positives = 128/277 (46%), Gaps = 36/277 (13%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYH 956
+K + +G G FG V L C T+ +V +K + + R + E +L+ L H
Sbjct 5 EKTKVVGRGAFGIVHL-CRRRTDSA---LVILKEIPVEQMTRDERLAAQNECQVLKLLSH 60
Query 957 EHIIKY-KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMA 1012
+II+Y + ED K+L + MEY P G+L DY+ + L +L QI +
Sbjct 61 PNIIEYYENFLED---KALMIAMEYAPGGTLADYIQKRCNSLLDEDTILHSFVQILLALY 117
Query 1013 YLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
++H + +HRDL +N+LLD ++ VKIGDFG++K + + Y V +P + +PE
Sbjct 118 HVHNKLILHRDLKTQNILLDKHQMIVKIGDFGISKILVSKSKAYTVV---GTPCY-ISPE 173
Query 1072 CLKEYKFYYASDVWSFGVTLYEL--LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
+ + SD+W+ G LYEL L + + P L+++
Sbjct 174 LCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMS---------------- 217
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
G P D+ E+ L+ N + S RP ++
Sbjct 218 -GTFAPISDRYSPELRQLILNMLNLDPSKRPQLNEIM 253
>sp|Q1PDW3|LIPG1_ARATH Receptor-like kinase LIP1 OS=Arabidopsis
thaliana OX=3702 GN=LIP1 PE=1 SV=1
Length=636
Score = 87.0 bits (214), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 72/202 (36%), Positives = 99/202 (49%), Gaps = 15/202 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG+V Y T TG++VAVK L G + E+ L L H +++K
Sbjct 80 LGEGGFGRV----YKGTLQSTGQLVAVKQLDKH-GLHGNKEFLAEVLSLAKLEHPNLVKL 134
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017
G C D G++ L LV EYV GSL+D+L G + + A +G+ YLH +
Sbjct 135 IGYCAD-GDQRL-LVFEYVSGGSLQDHLYEQKPGQKPMDWITRMKIAFGAAQGLDYLHDK 192
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
I+RDL A N+LLD + K+ DFGL P + + + APE +
Sbjct 193 VTPAVIYRDLKASNILLDAEFYPKLCDFGLHNLEPGTGDSLFLSSRVMDTYGYSAPEYTR 252
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
SDV+SFGV L EL+T
Sbjct 253 GDDLTVKSDVYSFGVVLLELIT 274
Score = 65.1 bits (157), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 61/240 (25%), Positives = 103/240 (43%), Gaps = 42/240 (18%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAW--KMVVAQQL 718
++++ H +L + G C G + ++V EYV G L L ++ G PM W +M +A
Sbjct 123 LAKLEHPNLVKLIGYCADGDQRLLVFEYVSGGSLQDHLYEQKPGQKPMDWITRMKIAFGA 182
Query 719 ASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD-------PGVGLGALS 768
A L YL +K +++ ++ NILL + KL D PG G
Sbjct 183 AQGLDYLHDKVTPAVIYRDLKASNILL-------DAEFYPKLCDFGLHNLEPGTGDSLFL 235
Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF-- 826
++ + APE G + L+ D + FG LLE+ G + + P+++++
Sbjct 236 SSRVMDTYGYSAPEYTRG--DDLTVKSDVYSFGVVLLEL-ITGRRAIDTTKPNDEQNLVA 292
Query 827 -----YQRQHRLPEPSCP------------QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
++ R P+ + P Q +TS CL EPT RP ++ L+ L
Sbjct 293 WAQPIFKDPKRYPDMADPLLRKNFSERGLNQAVAITSMCLQEEPTARPLISDVMVALSFL 352
>sp|Q61UC4|KRAF1_CAEBR Raf homolog serine/threonine-protein kinase
OS=Caenorhabditis briggsae OX=6238 GN=lin-45 PE=3 SV=2
Length=811
Score = 87.4 bits (215), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 72/280 (26%), Positives = 126/280 (45%), Gaps = 30/280 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V Y GT VA+K L D P + +K E+ +L+ H +++
Sbjct 485 VGSGSFGTV----YRGEFFGT---VAIKKLNVVDPTPSQMAAFKNEVAVLKKTRHLNVLL 537
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G E + ++ ++ SL ++ PR ++ ++ +Q+ GM YLH++
Sbjct 538 FMGWVR---EPEIAIITQWCEGSSLYRHIHVQEPRVEFEMSAVIDILKQVSLGMNYLHSK 594
Query 1018 HYIHRDLAARNV-LLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLK- 1074
+ IHRDL N+ L+D+ VKIGDFGLA + + ++ + W APE ++
Sbjct 595 NIIHRDLKTNNIFLMDDMSTVKIGDFGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRM 654
Query 1075 --EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + SDV+SFGV +YE+L + L I + + + +
Sbjct 655 QDDNPYTPQSDVYSFGVCMYEIL----------SSHLPYSNINNRDQILFMVGRGYLKPD 704
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
R P + L NC + + RP F ++ L+ +
Sbjct 705 RSKIRTDTPKSLMKLYDNCIMFDRNERPVFGEVLERLRDI 744
Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 57/246 (23%), Positives = 107/246 (43%), Gaps = 31/246 (13%)
Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVW 698
L V+DP+ +A AF +++ + H ++ G VR PE ++T++ E L +
Sbjct 507 LNVVDPTPSQMA-AFKNEVAVLKKTRHLNVLLFMG-WVREPEIAIITQWCEGSSLYRHIH 564
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
++ R M+ + + +Q++ ++YL +KN++H ++ NI L +K+
Sbjct 565 VQEPRVEFEMSAVIDILKQVSLGMNYLHSKNIIHRDLKTNNIFLM------DDMSTVKIG 618
Query 759 DPGVGLGALSREERVE----------RIPWLAPECLP-GGANSLSTAMDKWGFGATLLEI 807
D GL + + V I W+APE + N + D + FG + EI
Sbjct 619 D--FGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGVCMYEI 676
Query 808 CFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQRPSFR 860
P + + ++ F R + P+ S P+ L L C+ ++ +RP F
Sbjct 677 -LSSHLPYSNINNRDQILFMVGRGYLKPDRSKIRTDTPKSLMKLYDNCIMFDRNERPVFG 735
Query 861 TILRDL 866
+L L
Sbjct 736 EVLERL 741
>sp|I1RNG8|ATG1_GIBZE Serine/threonine-protein kinase ATG1 OS=Gibberella
zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075
/ NRRL 31084 / PH-1) OX=229533 GN=ATG1 PE=3 SV=1
Length=944
Score = 87.8 bits (216), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 80/316 (25%), Positives = 137/316 (43%), Gaps = 73/316 (23%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHII 960
++G+G F +V L + T VA+K+++ + + R EI IL+TL H HI+
Sbjct 29 EIGKGSFAQVYLGWHKETKAA----VAIKSVELERLNKKLRENLYSEIQILKTLRHPHIV 84
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSL------RDYLPRH--------------SIGLAQL 1000
C E + L+MEY LG L R+ L H + GL ++
Sbjct 85 ALHDCIESTSH--INLIMEYCELGDLSLFIKKREKLATHPATHDMARKYPSMPNSGLHEV 142
Query 1001 LL--FAQQICEGMAYLHAQHYIHRDLAARNVLL-----------------DNDRLV---- 1037
++ F +Q+ + +L +++Y+HRD+ +N+LL D L+
Sbjct 143 VIRHFLKQLTSALEFLRSKNYVHRDVKPQNLLLLPSQPFRDQRSRPVMQASQDSLIPISG 202
Query 1038 -------KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
K+ DFG A+ +P + SP++ APE L+ ++ +D+WS G
Sbjct 203 LASLPMLKLADFGFARVLPSTSLADTL---CGSPLYM-APEILRYERYDAKADLWSVGTV 258
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
LYE+ S+ PP + A+ + +LR E E + PR E+ L+++
Sbjct 259 LYEM-----STGRPPFR-------ARNHVELLRKIEAAEDVIKFPREVSITPELKALIRS 306
Query 1151 CWETEASFRPTFENLI 1166
+ R +FEN
Sbjct 307 LLKRSPVERLSFENFF 322
Score = 39.7 bits (91), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 64/261 (25%), Positives = 103/261 (39%), Gaps = 58/261 (22%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVP------ 707
Y ++ + H H+ +H C+ +I ++ EY E G L +++++
Sbjct 68 LYSEIQILKTLRHPHIVALHD-CIESTSHINLIMEYCELGDLSLFIKKREKLATHPATHD 126
Query 708 MAWK-----------MVVA---QQLASALSYLENKNLVHGNVCGRNILL----------A 743
MA K +V+ +QL SAL +L +KN VH +V +N+LL +
Sbjct 127 MARKYPSMPNSGLHEVVIRHFLKQLTSALEFLRSKNYVHRDVKPQNLLLLPSQPFRDQRS 186
Query 744 R-------------LGLAEGTSPFIKLSDPGVG--LGALSREERVERIP-WLAPECLPGG 787
R GLA + P +KL+D G L + S + + P ++APE L
Sbjct 187 RPVMQASQDSLIPISGLA--SLPMLKLADFGFARVLPSTSLADTLCGSPLYMAPEIL--R 242
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE---KEHFYQRQHRLPEPS--CPQLA 842
D W G L E+ G P ++R+ E K + + P P+L
Sbjct 243 YERYDAKADLWSVGTVLYEMS-TGRPPFRARNHVELLRKIEAAEDVIKFPREVSITPELK 301
Query 843 TLTSQCLTYEPTQRPSFRTIL 863
L L P +R SF
Sbjct 302 ALIRSLLKRSPVERLSFENFF 322
>sp|Q9LSE1|CDG1_ARATH Serine/threonine-protein kinase CDG1 OS=Arabidopsis
thaliana OX=3702 GN=CDG1 PE=1 SV=1
Length=432
Score = 85.9 bits (211), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 70/203 (34%), Positives = 103/203 (51%), Gaps = 19/203 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V TG+ +AVK L G Q + E+ +L L+H +++
Sbjct 80 IGRGGFGTVY-----KGRLSTGQNIAVKMLD-QSGIQGDKEFLVEVLMLSLLHHRNLVHL 133
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017
G C +G++ L +V EY+PLGS+ D+L S G L + A +G+A+LH +
Sbjct 134 FGYCA-EGDQRL-VVYEYMPLGSVEDHLYDLSEGQEALDWKTRMKIALGAAKGLAFLHNE 191
Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECL 1073
I+RDL N+LLD+D K+ DFGLAK P + + R G + APE
Sbjct 192 AQPPVIYRDLKTSNILLDHDYKPKLSDFGLAKFGPSDDMSHVSTRVMGTHG--YCAPEYA 249
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
K SD++SFGV L EL++
Sbjct 250 NTGKLTLKSDIYSFGVVLLELIS 272
Score = 44.3 bits (103), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 59/222 (27%), Positives = 90/222 (41%), Gaps = 36/222 (16%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
S +G+G VY+GRL GQ + V K+LD S
Sbjct 78 SLIGRGGFGTVYKGRLST-----------------------GQNIAV--KMLDQSGIQGD 112
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAWK 711
F ++S + H +L + G C G + ++V EY+ G ++ L G + WK
Sbjct 113 KEFLVEVLMLSLLHHRNLVHLFGYCAEGDQRLVVYEYMPLGSVEDHLYDLSEGQEALDWK 172
Query 712 --MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALS 768
M +A A L++L N+ V R++ + + L P KLSD G+ G
Sbjct 173 TRMKIALGAAKGLAFLHNE--AQPPVIYRDLKTSNILLDHDYKP--KLSDFGLAKFGPSD 228
Query 769 REERVE-RIPWLAPECLPGGANS--LSTAMDKWGFGATLLEI 807
V R+ C P AN+ L+ D + FG LLE+
Sbjct 229 DMSHVSTRVMGTHGYCAPEYANTGKLTLKSDIYSFGVVLLEL 270
>sp|Q9FYK0|TMK2_ARATH Receptor-like kinase TMK2 OS=Arabidopsis
thaliana OX=3702 GN=TMK2 PE=1 SV=1
Length=886
Score = 87.4 bits (215), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 71/205 (35%), Positives = 100/205 (49%), Gaps = 21/205 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
LG G FG V +DGT +AVK +++ + +K EI +L + H +++
Sbjct 553 LGRGGFGIV---YKGELHDGT--KIAVKRMESSIISGKGLDEFKSEIAVLTRVRHRNLVV 607
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSL-RDYLPRHSIGLAQL-----LLFAQQICEGMAYLH 1015
G C + E+ LV +Y+P G+L R GL L L+ A + G+ YLH
Sbjct 608 LHGYCLEGNER--LLVYQYMPQGTLSRHIFYWKEEGLRPLEWTRRLIIALDVARGVEYLH 665
Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APE 1071
Q +IHRDL N+LL +D K+ DFGL + PEG + + G F Y APE
Sbjct 666 TLAHQSFIHRDLKPSNILLGDDMHAKVADFGLVRLAPEGTQSIETKIAG---TFGYLAPE 722
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
+ DV+SFGV L ELLT
Sbjct 723 YAVTGRVTTKVDVYSFGVILMELLT 747
Score = 63.5 bits (153), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 59/235 (25%), Positives = 107/235 (46%), Gaps = 42/235 (18%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD--VWLRRERGHVPMAW-- 710
F +++++V H +L +HG C+ G E ++V +Y+ G L ++ +E G P+ W
Sbjct 590 FKSEIAVLTRVRHRNLVVLHGYCLEGNERLLVYQYMPQGTLSRHIFYWKEEGLRPLEWTR 649
Query 711 KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--- 764
++++A +A + YL ++ +H ++ NILL G K++D G+
Sbjct 650 RLIIALDVARGVEYLHTLAHQSFIHRDLKPSNILL-------GDDMHAKVADFGLVRLAP 702
Query 765 -GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
G S E ++ +LAPE G ++T +D + FG L+E+ G L E
Sbjct 703 EGTQSIETKIAGTFGYLAPEYAVTG--RVTTKVDVYSFGVILMEL-LTGRKALDVARSEE 759
Query 823 KEHF--YQRQHRLPEPSCPQ------------------LATLTSQCLTYEPTQRP 857
+ H + R+ + + S P+ +A L +QC + EP RP
Sbjct 760 EVHLATWFRRMFINKGSFPKAIDEAMEVNEETLRSINIVAELANQCSSREPRDRP 814
>sp|P0C8M8|CCR1_MAIZE Probable serine/threonine-protein kinase
CCRP1 OS=Zea mays OX=4577 GN=CCRP1 PE=1 SV=1
Length=626
Score = 87.0 bits (214), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 67/214 (31%), Positives = 111/214 (52%), Gaps = 16/214 (7%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
++PT+ R K R LG+G F K CY+ TN +++A K + + R+ K
Sbjct 28 GTEPTI---RKYSKGRMLGKGGFAK----CYEVTNLENKKVLAGKIICKASLTKSRAKQK 80
Query 946 --QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLL 1002
EI I ++L H +I++++ EDQ +++ +++E P SL D + R + ++
Sbjct 81 LISEIKIHKSLRHSNIVEFEHVFEDQ--ENVYILLELCPNQSLHDLIKRRKRLTEIEVQC 138
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
+ Q+ G+ YLH++ IHRDL N+LL++ +KI DFGLA + E R+
Sbjct 139 YTLQLICGLKYLHSRRVIHRDLKLGNLLLNDKMELKICDFGLAAKLEFDGEK---RKTVC 195
Query 1063 SPVFWYAPECLK-EYKFYYASDVWSFGVTLYELL 1095
+ APE ++ + Y D WS GV +Y LL
Sbjct 196 GTPNYIAPEVIEGKGGHSYEVDTWSLGVIIYTLL 229
Score = 35.0 bits (79), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 37/158 (23%), Positives = 69/158 (44%), Gaps = 22/158 (14%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI 776
QL L YL ++ ++H R++ L L L + +K+ D G+ E+ + +
Sbjct 142 QLICGLKYLHSRRVIH-----RDLKLGNLLLNDKME--LKICDFGLAAKLEFDGEKRKTV 194
Query 777 ----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR--- 829
++APE + G S +D W G + + G P ++ S+ + Y+R
Sbjct 195 CGTPNYIAPEVIEGKGGH-SYEVDTWSLGVIIYTLLV-GRPPFET---SDVKQTYKRIKA 249
Query 830 -QHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILR 864
++ P+ L + LT +P++RPS IL+
Sbjct 250 CEYSFPDHVSVSDTAKNLVQKMLTLDPSKRPSLDEILQ 287
>sp|F4IRW0|ATG1C_ARATH Serine/threonine-protein kinase ATG1c OS=Arabidopsis
thaliana OX=3702 GN=ATG1C PE=2 SV=1
Length=733
Score = 87.0 bits (214), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 74/235 (31%), Positives = 116/235 (49%), Gaps = 29/235 (12%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHI 959
R +G G F V ++ + G VA+K + D + + EI ILR + H +I
Sbjct 16 RQIGSGSFSVV----WEARHRVDGTEVAIKEIAMDRLNKKLQESLMSEIFILRRINHPNI 71
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLHAQH 1018
I+ + G+ + LV+EY G L Y+ RH I A F QQ+ G+ L +
Sbjct 72 IRLIDMIKSPGK--VHLVLEYCKGGDLSVYVQRHGIVPEATAKHFMQQLAAGLQVLRDNN 129
Query 1019 YIHRDLAARNVLL---DNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL +N+LL +ND +KI DFG A+++ P G + E + APE ++
Sbjct 130 IIHRDLKPQNLLLSTNENDADLKIADFGFARSLQPRG-----LAETLCGSPLYMAPEIMQ 184
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM--TVLRLTEL 1127
K+ +D+WS G L++L+T ++P T G +Q Q+ ++R TEL
Sbjct 185 LQKYDAKADLWSVGAILFQLVT----GRTPFT------GNSQIQLLQNIIRSTEL 229
Score = 47.4 bits (111), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 60/275 (22%), Positives = 111/275 (40%), Gaps = 40/275 (15%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
+G G+ + V+E R RV+G+ E+ + +D + +
Sbjct 17 QIGSGSFSVVWEARHRVDGT----------------------EVAIKEIAMDRLNKKLQE 54
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKM 712
+ ++ +++H ++ + + ++ P + +V EY + G L V+++R G VP A
Sbjct 55 SLMSEIFILRRINHPNIIRLIDM-IKSPGKVHLVLEYCKGGDLSVYVQRH-GIVPEATAK 112
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR--- 769
QQLA+ L L + N++H ++ +N+LL+ +K++D G R
Sbjct 113 HFMQQLAAGLQVLRDNNIIHRDLKPQNLLLS----TNENDADLKIADFGFARSLQPRGLA 168
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
E ++APE + D W GA L ++ G P S + R
Sbjct 169 ETLCGSPLYMAPEIMQ--LQKYDAKADLWSVGAILFQLV-TGRTPFTGNSQIQLLQNIIR 225
Query 830 QHRLPEP-SCPQLA----TLTSQCLTYEPTQRPSF 859
L P C L+ L + L P +R +F
Sbjct 226 STELHFPGDCRDLSLDCIDLCQKLLRRNPVERLTF 260
>sp|J4W0G2|ATG1_BEAB2 Serine/threonine-protein kinase ATG1 OS=Beauveria
bassiana (strain ARSEF 2860) OX=655819 GN=ATG1 PE=2
SV=1
Length=930
Score = 87.4 bits (215), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 79/316 (25%), Positives = 138/316 (44%), Gaps = 73/316 (23%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHI 959
R++G+G F +V + + + VA+K+++ + + + EI IL+TL H HI
Sbjct 27 REIGKGSFAQVYMGWHKESKAA----VAIKSVELERLNKKLKENLYGEIQILKTLRHPHI 82
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSL------RDYLPRH--------------SIGLAQ 999
+ C E + L+MEY LG L RD L H + GL +
Sbjct 83 VALHDCVESSTH--INLIMEYCELGDLSLFIKKRDKLITHPATHDMARKYPSAPNSGLHE 140
Query 1000 LLL--FAQQICEGMAYLHAQHYIHRDLAARNVLL-----------------DNDRLV--- 1037
+++ F +Q+ + +L A++Y+HRD+ +N+LL D L+
Sbjct 141 VVIRHFLKQLSSALEFLRAKNYVHRDVKPQNLLLLPSQAFREERALPIMEASQDSLIPIS 200
Query 1038 --------KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
K+ DFG A+ +P + SP++ APE L+ ++ +D+WS G
Sbjct 201 GLASLPMLKLADFGFARVLPSTSLADTL---CGSPLYM-APEILRYERYDAKADLWSVGT 256
Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149
LYE++T PP + A+ + +LR E E + PR ++ L++
Sbjct 257 VLYEMITG-----RPPFR-------ARNHVELLRKIEAAEDVIKFPREVSVTPDLKALVR 304
Query 1150 NCWETEASFRPTFENL 1165
+ + R +FEN
Sbjct 305 SLLKRSPVERLSFENF 320
Score = 42.0 bits (97), Expect = 0.042, Method: Compositional matrix adjust.
Identities = 63/259 (24%), Positives = 99/259 (38%), Gaps = 54/259 (21%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVP------ 707
Y ++ + H H+ +H CV +I ++ EY E G L +++++ +
Sbjct 67 LYGEIQILKTLRHPHIVALHD-CVESSTHINLIMEYCELGDLSLFIKKRDKLITHPATHD 125
Query 708 MAWKMVVA--------------QQLASALSYLENKNLVHGNVCGRNILL---------AR 744
MA K A +QL+SAL +L KN VH +V +N+LL
Sbjct 126 MARKYPSAPNSGLHEVVIRHFLKQLSSALEFLRAKNYVHRDVKPQNLLLLPSQAFREERA 185
Query 745 LGLAEGTS------------PFIKLSDPGVG--LGALSREERVERIP-WLAPECLPGGAN 789
L + E + P +KL+D G L + S + + P ++APE L
Sbjct 186 LPIMEASQDSLIPISGLASLPMLKLADFGFARVLPSTSLADTLCGSPLYMAPEIL--RYE 243
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE---KEHFYQRQHRLPE--PSCPQLATL 844
D W G L E+ G P ++R+ E K + + P P L L
Sbjct 244 RYDAKADLWSVGTVLYEM-ITGRPPFRARNHVELLRKIEAAEDVIKFPREVSVTPDLKAL 302
Query 845 TSQCLTYEPTQRPSFRTIL 863
L P +R SF
Sbjct 303 VRSLLKRSPVERLSFENFF 321
>sp|Q863I2|OXSR1_PIG Serine/threonine-protein kinase OSR1 OS=Sus
scrofa OX=9823 GN=OXSR1 PE=2 SV=1
Length=529
Score = 86.3 bits (212), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 62/200 (31%), Positives = 98/200 (49%), Gaps = 15/200 (8%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
E VA+K + + +EI + +H +I+ Y + E L LVM+ + G
Sbjct 41 EKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGG 98
Query 985 SLRDYLP------RHSIGL---AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035
S+ D + H G+ A + +++ EG+ YLH IHRD+ A N+LL D
Sbjct 99 SVLDIIKHIVAKGEHKSGVLDEATIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG 158
Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092
V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T
Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAI 218
Query 1093 ELLTHCDS-SQSPPTKFLEL 1111
EL T + PP K L L
Sbjct 219 ELATGAAPYHKYPPMKVLML 238
Score = 37.7 bits (86), Expect = 0.70, Method: Compositional matrix adjust.
Identities = 54/227 (24%), Positives = 87/227 (38%), Gaps = 30/227 (13%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWL------RRERGHVPMAWKMVV 714
MSQ H ++ + V E +V + + G LD+ + G + A +
Sbjct 67 MSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEATIATI 126
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALSRE 770
+++ L YL +H +V NILL G + G S F L+ G R+
Sbjct 127 LREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAF--LATGGDITRNKVRK 184
Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------LQS 817
V W+APE + D W FG T +E+ G AP LQ+
Sbjct 185 TFVGTPCWMAPEVME-QVRGYDFKADIWSFGITAIELA-TGAAPYHKYPPMKVLMLTLQN 242
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
PS + ++ + + + S CL +P +RP+ +LR
Sbjct 243 DPPSLETGVQDKE--MLKKYGKSFRKMISLCLQKDPEKRPTAAELLR 287
>sp|O81833|SD11_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase SD1-1 OS=Arabidopsis thaliana OX=3702
GN=SD11 PE=1 SV=1
Length=815
Score = 87.0 bits (214), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 73/205 (36%), Positives = 103/205 (50%), Gaps = 24/205 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG G FG P G G+ +AVK L A+ G Q +K E+ ++ L H ++
Sbjct 506 LGRGGFG--------PVYKGKLEDGQEIAVKRLSANSG-QGVEEFKNEVKLIAKLQHRNL 556
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMAYLH 1015
++ GCC QGE+ + L+ EY+P SL ++ R S L + + + G+ YLH
Sbjct 557 VRLLGCCI-QGEECM-LIYEYMPNKSLDFFIFDERRSTELDWKKRMNIINGVARGILYLH 614
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA-PE 1071
IHRDL A NVLLDND KI DFGLAK+ G + + + Y PE
Sbjct 615 QDSRLRIIHRDLKAGNVLLDNDMNPKISDFGLAKSF--GGDQSESSTNRVVGTYGYMPPE 672
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
+ F SDV+SFGV + E++T
Sbjct 673 YAIDGHFSVKSDVFSFGVLVLEIIT 697
Score = 53.9 bits (128), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 50/194 (26%), Positives = 88/194 (45%), Gaps = 23/194 (12%)
Query 626 PLVPGR-DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
P+ G+ + GQE+ V K L + F L++++ H +L + G C++G E +
Sbjct 513 PVYKGKLEDGQEIAV--KRLSANSGQGVEEFKNEVKLIAKLQHRNLVRLLGCCIQGEECM 570
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWK--MVVAQQLASALSYLENKN---LVHGNVCGRN 739
++ EY+ + LD ++ ER + WK M + +A + YL + ++H ++ N
Sbjct 571 LIYEYMPNKSLDFFIFDERRSTELDWKKRMNIINGVARGILYLHQDSRLRIIHRDLKAGN 630
Query 740 ILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERI----PWLAPECLPGGANSLST 793
+L L +P K+SD G+ G E R+ ++ PE G S
Sbjct 631 VL-----LDNDMNP--KISDFGLAKSFGGDQSESSTNRVVGTYGYMPPEYAIDG--HFSV 681
Query 794 AMDKWGFGATLLEI 807
D + FG +LEI
Sbjct 682 KSDVFSFGVLVLEI 695
>sp|Q54XL6|FRAY1_DICDI Serine/threonine-protein kinase fray1 OS=Dictyostelium
discoideum OX=44689 GN=fray1 PE=3 SV=1
Length=574
Score = 86.7 bits (213), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 79/277 (29%), Positives = 129/277 (47%), Gaps = 34/277 (12%)
Query 900 IRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHE 957
I +GEG G+V YC E VA+K ++ D PQ +E+ ++ H
Sbjct 100 IEPIGEGTEGRVFKAYCIP-----LKENVAIKVVELDKMDPQFVKDVIKEVKVMNGNNHP 154
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFA--QQICEGMAYL 1014
++I Y + + L LVM+Y+ GSL D + ++ G+ ++L + + +G+ YL
Sbjct 155 NLIHYHTSFLENNQ--LWLVMDYLGGGSLADIMKFKYPDGIPEVLAVTVLKSLLKGLEYL 212
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H+ IHRDL + N+L+ D +++ DFG++ A+ E + + +P W APE +
Sbjct 213 HSHQRIHRDLKSDNILIGEDGAIELADFGVS-AMFEKNTCCSRKTIVGTPC-WMAPEIIS 270
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQMTVLRLTELLERGER 1133
E + D+WSFG+T EL+ PP+K + + G L+ E
Sbjct 271 ERGYNQGVDIWSFGITAIELIRGKPPGYDLPPSKV--FMNLLFGNSPSLQEEE------- 321
Query 1134 LPRPDKCPCEVYHLMKN----CWETEASFRPTFENLI 1166
DK C HL K+ C + E S RP L+
Sbjct 322 ----DKGVCS--HLYKDLVDKCLQKEPSKRPNASKLL 352
Score = 50.8 bits (120), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 58/238 (24%), Positives = 96/238 (40%), Gaps = 26/238 (11%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DV 697
V L +DP + +M+ +H +L H + + +V +Y+ G L D+
Sbjct 128 VELDKMDPQ---FVKDVIKEVKVMNGNNHPNLIHYHTSFLENNQLWLVMDYLGGGSLADI 184
Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ +P + V + L L YL + +H ++ NIL+ G I+L
Sbjct 185 MKFKYPDGIPEVLAVTVLKSLLKGLEYLHSHQRIHRDLKSDNILIGEDGA-------IEL 237
Query 758 SDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
+D GV SR+ V W+APE + + +D W FG T +E+ G+
Sbjct 238 ADFGVSAMFEKNTCCSRKTIVGTPCWMAPEII--SERGYNQGVDIWSFGITAIEL-IRGK 294
Query 813 APLQSRSPSE--KEHFYQRQHRLPEPS----CPQL-ATLTSQCLTYEPTQRPSFRTIL 863
P PS+ + L E C L L +CL EP++RP+ +L
Sbjct 295 PPGYDLPPSKVFMNLLFGNSPSLQEEEDKGVCSHLYKDLVDKCLQKEPSKRPNASKLL 352
>sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo
sapiens OX=9606 GN=NEK9 PE=1 SV=2
Length=979
Score = 87.4 bits (215), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 78/278 (28%), Positives = 132/278 (47%), Gaps = 30/278 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEH 958
IR LG G FG+ +LY T D + +V K + + R EI IL L H++
Sbjct 55 IRVLGRGAFGEATLY--RRTEDDS--LVVWKEVDLTRLSEKERRDALNEIVILALLQHDN 110
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMAYLH 1015
II Y D +L + +EY G+L D + R L + ++ + QI ++ +H
Sbjct 111 IIAYYNHFMDN--TTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIH 168
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRD+ N+ L L+K+GD+GLAK + + Y + E ++ +PE +
Sbjct 169 KAGILHRDIKTLNIFLTKANLIKLGDYGLAKKL---NSEYSMAETLVGTPYYMSPELCQG 225
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL-IGIAQGQMTVLRLTELLERGERL 1134
K+ + SD+W+ G ++ELLT + + T L L + I QG +R E+ L
Sbjct 226 VKYNFKSDIWAVGCVIFELLTLKRTFDA--TNPLNLCVKIVQG----IRAMEVDSSQYSL 279
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILK 1170
E+ ++ +C + + RPT + L+ P+L+
Sbjct 280 --------ELIQMVHSCLDQDPEQRPTADELLDRPLLR 309
>sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens
OX=9606 GN=PRKCD PE=1 SV=2
Length=676
Score = 87.0 bits (214), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 76/217 (35%), Positives = 104/217 (48%), Gaps = 22/217 (10%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG--PQHRSGWKQEI 948
+FHK LG+G FGKV L G GE A+KALK D E
Sbjct 350 IFHKV-------LGKGSFGKVLL----GELKGRGEYFAIKALKKDVVLIDDDVECTMVEK 398
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQI 1007
+L TL E+ C Q + L VME++ G L ++ + L + +A +I
Sbjct 399 RVL-TLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEI 457
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
G+ +LH++ I+RDL NVLLD D +KI DFG+ K G R +P +
Sbjct 458 MCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGES--RASTFCGTPDY- 514
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
APE L+ K+ ++ D WSFGV LYE+L QSP
Sbjct 515 IAPEILQGLKYTFSVDWWSFGVLLYEMLI----GQSP 547
>sp|Q0D541|WNK5_ORYSJ Probable serine/threonine-protein kinase
WNK5 OS=Oryza sativa subsp. japonica OX=39947 GN=WNK5 PE=2
SV=1
Length=327
Score = 84.3 bits (207), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 64/184 (35%), Positives = 95/184 (52%), Gaps = 16/184 (9%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
V ++AL AD P E+ +LR+L+HEHII + D+ L + E GSL
Sbjct 86 VRLRAL-ADRDPAMVERLHAEVRLLRSLHHEHIIGFHKVWLDRDAGVLNFITEVCTSGSL 144
Query 987 RDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDF 1042
R+Y RH + + L +A+QI G+ +LH IHRDL NV ++ N VKIGD
Sbjct 145 REYRDRHRHVSVKALKKWARQILLGLDHLHTHDPCIIHRDLNCSNVFINGNTGQVKIGDL 204
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT------ 1096
GLA V + H + + +P F APE E + + D++S+G+ + E++T
Sbjct 205 GLAAIVDKTHVAHTIL---GTPEFM-APELYTE-TYTESVDIYSYGMCVLEMVTREMPYA 259
Query 1097 HCDS 1100
CDS
Sbjct 260 ECDS 263
>sp|Q9FN93|Y5596_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At5g59680 OS=Arabidopsis thaliana OX=3702
GN=At5g59680 PE=1 SV=1
Length=887
Score = 87.0 bits (214), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 58/180 (32%), Positives = 92/180 (51%), Gaps = 11/180 (6%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
E VAVK L + Q +K E+D+L ++H +++ G C D+G+ L L+ E+VP G
Sbjct 603 EQVAVKLL-SQSSTQGYKEFKAEVDLLLRVHHTNLVSLVGYC-DEGDH-LALIYEFVPNG 659
Query 985 SLRDYLP----RHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLV 1037
LR +L + + L A + G+ YLH +HRD+ N+LLD
Sbjct 660 DLRQHLSGKGGKPIVNWGTRLRIAAEAALGLEYLHIGCTPPMVHRDVKTTNILLDEHYKA 719
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
K+ DFGL+++ P G E + +P + PE + SDV+SFG+ L E++T+
Sbjct 720 KLADFGLSRSFPVGGESHVSTVIAGTPGY-LDPEYYHTSRLSEKSDVYSFGIVLLEMITN 778
Score = 41.6 bits (96), Expect = 0.052, Method: Compositional matrix adjust.
Identities = 57/210 (27%), Positives = 87/210 (41%), Gaps = 24/210 (11%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G G E +V +K+L S F L+ +V HT+L + G C G ++ E+
Sbjct 597 GTVNGSE-QVAVKLLSQSSTQGYKEFKAEVDLLLRVHHTNLVSLVGYCDEGDHLALIYEF 655
Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLAR 744
V +G L L + G + W ++ +A + A L YL +VH +V NILL
Sbjct 656 VPNGDLRQHLSGKGGKPIVNWGTRLRIAAEAALGLEYLHIGCTPPMVHRDVKTTNILLDE 715
Query 745 LGLAEGTSPFIKLSDPGVGLG-ALSREERVERI-----PWLAPECLPGGANSLSTAMDKW 798
A KL+D G+ + E V + +L PE + LS D +
Sbjct 716 HYKA-------KLADFGLSRSFPVGGESHVSTVIAGTPGYLDPEYY--HTSRLSEKSDVY 766
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
FG LLE+ + ++R K H Q
Sbjct 767 SFGIVLLEMITNQAVIDRNR---RKSHITQ 793
>sp|Q1DN93|ATG1_COCIM Serine/threonine-protein kinase ATG1 OS=Coccidioides
immitis (strain RS) OX=246410 GN=ATG1 PE=3 SV=1
Length=969
Score = 87.4 bits (215), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 68/250 (27%), Positives = 110/250 (44%), Gaps = 63/250 (25%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHE 957
KI ++G G F V Y ++ VA+KA+ + P+ + K EI+IL+ L H
Sbjct 32 KIEEIGRGSFATV----YQGIHNKYRSCVAIKAVNISSLNPKLKDNLKLEIEILKGLQHP 87
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSL------RDYLPRHSI--------------GL 997
HI+ C D+ + LVMEY LG L RD L +H + GL
Sbjct 88 HIVALIDC--DESTSCIHLVMEYCALGDLSLFIRKRDTLSKHELTRDMIAKYPNPPAGGL 145
Query 998 AQLLL--FAQQICEGMAYLHAQHYIHRDLAARNVLLD-------------------NDR- 1035
++++ F +Q+ + +L + IHRDL +N+LL+ D
Sbjct 146 NEVIVRHFLKQLASALQFLRTKDLIHRDLKPQNLLLNPPPSTYAKGLLRIVPYKTREDSF 205
Query 1036 ----------LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
++KI DFG A+++P + E + APE L+ K+ +D+W
Sbjct 206 TPLVGVESLPMLKIADFGFARSLPATS----LAETLCGSPLYMAPEILRYEKYDAKADLW 261
Query 1086 SFGVTLYELL 1095
S G L+E++
Sbjct 262 SVGTVLFEMV 271
>sp|P32490|MKK1_YEAST MAP kinase kinase MKK1/SSP32 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MKK1
PE=1 SV=1
Length=508
Score = 86.3 bits (212), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 58/197 (29%), Positives = 95/197 (48%), Gaps = 13/197 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG G VS C + + L D P+++ +E+ R+ E+I++Y
Sbjct 227 LGEGAGGSVS-KCKLKNGSKIFALKVINTLNTD--PEYQKQIFRELQFNRSFQSEYIVRY 283
Query 963 KGCCEDQGEKSLQLVMEYVPLGSL----RDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQ 1017
G D S+ + MEY+ SL ++ L R I L A+ + G++YLH +
Sbjct 284 YGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEK 343
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ +N+LL+ + VK+ DFG++ G + F+ APE ++
Sbjct 344 KVIHRDIKPQNILLNENGQVKLCDFGVS-----GEAVNSLATTFTGTSFYMAPERIQGQP 398
Query 1078 FYYASDVWSFGVTLYEL 1094
+ SDVWS G+T+ E+
Sbjct 399 YSVTSDVWSLGLTILEV 415
Score = 40.4 bits (93), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 42/166 (25%), Positives = 70/166 (42%), Gaps = 25/166 (15%)
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR--EE 771
+A+ + LSYL K ++H ++ +NILL G +KL D GV A++
Sbjct 329 IAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQ-------VKLCDFGVSGEAVNSLATT 381
Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-------- 823
++APE + G S+++ D W G T+LE+ +G+ P S +
Sbjct 382 FTGTSFYMAPERIQGQPYSVTS--DVWSLGLTILEVA-NGKFPCSSEKMAANIAPFELLM 438
Query 824 --EHFYQRQHRLPEPS---CPQLATLTSQCLTYEPTQRPSFRTILR 864
F PE + P + CL + +RPS R ++
Sbjct 439 WILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMIN 484
>sp|Q8W4P1|CDKC2_ARATH Cyclin-dependent kinase C-2 OS=Arabidopsis
thaliana OX=3702 GN=CDKC-2 PE=1 SV=2
Length=513
Score = 85.9 bits (211), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 67/222 (30%), Positives = 104/222 (47%), Gaps = 33/222 (15%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILR 952
+K+ +GEG +G+V Y TGE+VA+K ++ D R G+ +EI IL+
Sbjct 26 FEKLEQIGEGTYGQV----YMAKEIKTGEIVALKKIRMD---NEREGFPITAIREIKILK 78
Query 953 TLYHEHIIKYKGCC-------EDQGEK-------SLQLVMEYVP--LGSLRDYLPRHSIG 996
L+HE++I K +DQG+ + +V EY+ L L D P
Sbjct 79 KLHHENVIHLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLAD-RPGLRFT 137
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
+ Q+ + +Q+ G+ Y H +HRD+ N+L+DN+ +K+ DFGLA++ H
Sbjct 138 VPQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGNL 197
Query 1057 VREDGDSPVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096
WY P L K+ A D+WS G ELL
Sbjct 198 TNR---VITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLN 236
>sp|Q94C40|CIPKH_ARATH CBL-interacting serine/threonine-protein
kinase 17 OS=Arabidopsis thaliana OX=3702 GN=CIPK17 PE=1 SV=1
Length=432
Score = 85.5 bits (210), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 70/208 (34%), Positives = 103/208 (50%), Gaps = 23/208 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW--KQEIDILRTLYHEH 958
R LGEG+ KV + TGE A+K ++ C + + K+EI L+ L H +
Sbjct 15 RTLGEGNSAKVKF----AIDTLTGESFAIKIIEKSCITRLNVSFQIKREIRTLKVLKHPN 70
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
I++ + + + +V+E V G L D + + + Q QQ+ +G++Y H +
Sbjct 71 IVRLHEVLASKTK--IYMVLECVTGGDLFDRIVSKGKLSETQGRKMFQQLIDGVSYCHNK 128
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG------DSPVFWYAPE 1071
HRDL NVLLD +KI DFGL+ ++Y REDG SP + APE
Sbjct 129 GVFHRDLKLENVLLDAKGHIKITDFGLSAL----SQHY--REDGLLHTTCGSPN-YVAPE 181
Query 1072 CLKEYKFY-YASDVWSFGVTLYELLTHC 1098
L + ASD+WS GV LY +LT C
Sbjct 182 VLANEGYDGAASDIWSCGVILYVILTGC 209
Score = 37.7 bits (86), Expect = 0.75, Method: Compositional matrix adjust.
Identities = 43/152 (28%), Positives = 63/152 (41%), Gaps = 21/152 (14%)
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLASALS 723
+ H ++ +H V + MV E V G L D + + + KM QQL +S
Sbjct 66 LKHPNIVRLHEVLASKTKIYMVLECVTGGDLFDRIVSKGKLSETQGRKMF--QQLIDGVS 123
Query 724 YLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI------- 776
Y NK + H ++ N+LL G IK++D GL ALS+ R + +
Sbjct 124 YCHNKGVFHRDLKLENVLLDAKG-------HIKITD--FGLSALSQHYREDGLLHTTCGS 174
Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
++APE L A D W G L I
Sbjct 175 PNYVAPEVLANEGYD-GAASDIWSCGVILYVI 205
>sp|Q96285|LRK55_ARATH L-type lectin-domain containing receptor
kinase V.5 OS=Arabidopsis thaliana OX=3702 GN=LECRK55 PE=1
SV=1
Length=661
Score = 86.7 bits (213), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 85/295 (29%), Positives = 137/295 (46%), Gaps = 35/295 (12%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
K+ + LG+G FG+V Y T G+ +AVK D Q S + EI + L H
Sbjct 338 FKEKQLLGKGGFGQV----YKGTLPGSDAEIAVKRTSHDS-RQGMSEFLAEISTIGRLRH 392
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMA 1012
++++ G C + ++L LV +Y+P GSL YL R + Q + + +
Sbjct 393 PNLVRLLGYCRHK--ENLYLVYDYMPNGSLDKYLNRSENQERLTWEQRFRIIKDVATALL 450
Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068
+LH Q IHRD+ NVL+DN+ ++GDFGLAK +G + + G F Y
Sbjct 451 HLHQEWVQVIIHRDIKPANVLIDNEMNARLGDFGLAKLYDQGFDPETSKVAG---TFGYI 507
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
APE L+ + ++DV++FG+ + E++ C + +E + V + EL
Sbjct 508 APEFLRTGRATTSTDVYAFGLVMLEVV--CGR------RIIERRAAENEEYLVDWILELW 559
Query 1129 ERG------ERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILKTVHE 1174
E G E R ++ +V ++K C AS RP ++ IL V +
Sbjct 560 ENGKIFDAAEESIRQEQNRGQVELVLKLGVLCSHQAASIRPAMSVVMRILNGVSQ 614
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 62/258 (24%), Positives = 107/258 (41%), Gaps = 48/258 (19%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAW--K 711
F S + ++ H +L + G C R EN+ +V +Y+ +G LD +L R + W +
Sbjct 380 FLAEISTIGRLRHPNLVRLLGYC-RHKENLYLVYDYMPNGSLDKYLNRSENQERLTWEQR 438
Query 712 MVVAQQLASALSYLEN---KNLVHGNVCGRNILL-----ARLGLAEGTSPFIKLSDPGVG 763
+ + +A+AL +L + ++H ++ N+L+ ARL G KL D G
Sbjct 439 FRIIKDVATALLHLHQEWVQVIIHRDIKPANVLIDNEMNARL----GDFGLAKLYDQGFD 494
Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ ++APE L G + ST D + FG +LE+ G ++ R+ +
Sbjct 495 ---PETSKVAGTFGYIAPEFLRTGRATTST--DVYAFGLVMLEVVC-GRRIIERRAAENE 548
Query 824 EHFY---------------------QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
E+ Q Q+R +L L C + RP+ +
Sbjct 549 EYLVDWILELWENGKIFDAAEESIRQEQNRGQVELVLKLGVL---CSHQAASIRPAMSVV 605
Query 863 LRDLTRLQ--PHNLADVL 878
+R L + P NL DV+
Sbjct 606 MRILNGVSQLPDNLLDVV 623
>sp|Q9BYT3|STK33_HUMAN Serine/threonine-protein kinase 33 OS=Homo
sapiens OX=9606 GN=STK33 PE=1 SV=1
Length=514
Score = 85.9 bits (211), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 61/206 (30%), Positives = 99/206 (48%), Gaps = 19/206 (9%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
R LG+G FG V + T+ T A+K + K G ++E++IL+++ HEHI
Sbjct 120 RILGKGSFGIV----IEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHI 175
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQH 1018
I + E K + LVME G L++ L R + Q + +AYLH
Sbjct 176 IHLEQVFETP--KKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNND 233
Query 1019 YIHRDLAARNVLL------DNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+HRDL N+++ DN+ + +K+ DFGLA + ++ +P++ A
Sbjct 234 IVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA-VKKQSRSEAMLQATCGTPIY-MA 291
Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095
PE + + + D+WS GV +Y LL
Sbjct 292 PEVISAHDYSQQCDIWSIGVVMYMLL 317
Score = 53.9 bits (128), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 45/168 (27%), Positives = 78/168 (46%), Gaps = 13/168 (8%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
+++ V H H+ + V + +V E E G L L R +GH + Q LA
Sbjct 165 NILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDR-KGHFSENETRWIIQSLA 223
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF---IKLSDPGVGLGALSREERVERI 776
SA++YL N ++VH ++ NI++ + L + + IK++D G+ + SR E + +
Sbjct 224 SAIAYLHNNDIVHRDLKLENIMV-KSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQA 282
Query 777 P-----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
++APE + A+ S D W G + + GE P + S
Sbjct 283 TCGTPIYMAPEVI--SAHDYSQQCDIWSIGVVMY-MLLRGEPPFLASS 327
>sp|Q8S8Y8|WNK6_ARATH Probable serine/threonine-protein kinase
WNK6 OS=Arabidopsis thaliana OX=3702 GN=WNK6 PE=2 SV=1
Length=567
Score = 86.3 bits (212), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 66/223 (30%), Positives = 110/223 (49%), Gaps = 20/223 (9%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD---CG 937
+P+ DPT RY++ +G+G F V Y ++ G VA ++ D
Sbjct 15 DPEVLEVDPTF---RYIRYKEVIGKGAFKTV----YKAFDEVDGIEVAWNQVRIDDVLQS 67
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIG 996
P E+ +L++L H +II++ D K++ ++ E GSLR Y +H +
Sbjct 68 PNCLERLYSEVRLLKSLKHNNIIRFYNSWIDDKNKTVNIITELFTSGSLRHYRKKHRKVN 127
Query 997 LAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFGLAKAVPEGHE 1053
+ + +A+QI G+ YLH Q IHRDL N+ ++ N VKIGD GLA + + +
Sbjct 128 MKAVKNWARQILMGLRYLHGQEPPIIHRDLKCDNIFINGNHGEVKIGDLGLATVMEQANA 187
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+ +P F APE E + +D++SFG+ + E++T
Sbjct 188 KSVI----GTPEFM-APELYDE-NYNELADIYSFGMCMLEMVT 224
>sp|Q8RXG3|M2K5_ARATH Mitogen-activated protein kinase kinase
5 OS=Arabidopsis thaliana OX=3702 GN=MKK5 PE=1 SV=2
Length=348
Score = 84.3 bits (207), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 57/203 (28%), Positives = 105/203 (52%), Gaps = 17/203 (8%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+++ +G G G V + PT+ A+K + + R +EI+ILR++ H
Sbjct 70 LERVNRIGSGAGGTVYKVIHTPTS----RPFALKVIYGNHEDTVRRQICREIEILRSVDH 125
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016
+++K + GE +Q+++E++ GSL H +L ++QI G+AYLH
Sbjct 126 PNVVKCHDMFDHNGE--IQVLLEFMDQGSLEGA---HIWQEQELADLSRQILSGLAYLHR 180
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK-- 1074
+H +HRD+ N+L+++ + VKI DFG+++ + + + + + +PE +
Sbjct 181 RHIVHRDIKPSNLLINSAKNVKIADFGVSRILAQTMDPC---NSSVGTIAYMSPERINTD 237
Query 1075 -EYKFY--YASDVWSFGVTLYEL 1094
+ Y YA DVWS GV++ E
Sbjct 238 LNHGRYDGYAGDVWSLGVSILEF 260
Score = 38.5 bits (88), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 51/240 (21%), Positives = 101/240 (42%), Gaps = 32/240 (13%)
Query 641 LKVLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD--- 696
LKV+ +H D + ++ V H ++ H + E ++ E+++ G L+
Sbjct 98 LKVIYGNHEDTVRRQICREIEILRSVDHPNVVKCHDMFDHNGEIQVLLEFMDQGSLEGAH 157
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+W +E + ++Q+ S L+YL +++VH ++ N+L+ ++ +K
Sbjct 158 IWQEQELADL--------SRQILSGLAYLHRRHIVHRDIKPSNLLI-------NSAKNVK 202
Query 757 LSDPGVG-LGALSRE---ERVERIPWLAPECLPGGANS---LSTAMDKWGFGATLLEICF 809
++D GV + A + + V I +++PE + N A D W G ++LE +
Sbjct 203 IADFGVSRILAQTMDPCNSSVGTIAYMSPERINTDLNHGRYDGYAGDVWSLGVSILEF-Y 261
Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT-----LTSQCLTYEPTQRPSFRTILR 864
G P + P P A+ S CL +P +R S + +L+
Sbjct 262 LGRFPFAVSRQGDWASLMCAICMSQPPEAPATASQEFRHFVSCCLQSDPPKRWSAQQLLQ 321
>sp|Q4WJJ0|MKK2_ASPFU Mitogen-activated protein kinase kinae mkk2
OS=Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355
/ FGSC A1100 / Af293) OX=330879 GN=mkk2 PE=3 SV=1
Length=503
Score = 85.9 bits (211), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 59/213 (28%), Positives = 100/213 (47%), Gaps = 19/213 (9%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
++ + ++ LGEG G V+ C DG + A+K + D P + +E++ +
Sbjct 207 EQKKIIELGSLGEGAGGAVT-RCK--LKDGK-TVFALKIITTDPNPDVKKQIVRELNFNK 262
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQI 1007
EHI +Y G D+ ++ + ME+ GSL G L A+ +
Sbjct 263 DCASEHICRYYGAFMDKSTGTISIAMEFCEGGSLDSIYKEVKKLGGRTGEKVLGKIAEGV 322
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV-- 1065
G+ YLH++ IHRD+ N+LL + VK+ DFG++ + + D ++ +
Sbjct 323 LNGLTYLHSRKIIHRDIKPSNILLCRNGQVKLCDFGVSGE-------FGTKGDANTFIGT 375
Query 1066 -FWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
++ APE + + SDVWS GVTL E+ H
Sbjct 376 SYYMAPERITGQSYTITSDVWSLGVTLLEVAQH 408
Score = 41.2 bits (95), Expect = 0.063, Method: Compositional matrix adjust.
Identities = 52/234 (22%), Positives = 96/234 (41%), Gaps = 44/234 (19%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+QK+I +L LG+G V +L+ +GK LK++
Sbjct 207 EQKKIIELGSLGEGAGGAVTRCKLK--------DGKT----------------VFALKII 242
Query 645 --DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEYVEHGPLDVWLR 700
DP + D+ + + H+ +G + + E+ E G LD +
Sbjct 243 TTDP-NPDVKKQIVRELNFNKDCASEHICRYYGAFMDKSTGTISIAMEFCEGGSLDSIYK 301
Query 701 RER---GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ G +A+ + + L+YL ++ ++H ++ NILL R G +KL
Sbjct 302 EVKKLGGRTGEKVLGKIAEGVLNGLTYLHSRKIIHRDIKPSNILLCRNGQ-------VKL 354
Query 758 SDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
D GV ++ + I ++APE + G + ++++ D W G TLLE+
Sbjct 355 CDFGVSGEFGTKGDANTFIGTSYYMAPERITGQSYTITS--DVWSLGVTLLEVA 406
>sp|B0XPE4|MKK2_ASPFC Mitogen-activated protein kinase kinae mkk2
OS=Aspergillus fumigatus (strain CBS 144.89 / FGSC A1163
/ CEA10) OX=451804 GN=mkk2 PE=3 SV=1
Length=503
Score = 85.9 bits (211), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 59/213 (28%), Positives = 100/213 (47%), Gaps = 19/213 (9%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
++ + ++ LGEG G V+ C DG + A+K + D P + +E++ +
Sbjct 207 EQKKIIELGSLGEGAGGAVT-RCK--LKDGK-TVFALKIITTDPNPDVKKQIVRELNFNK 262
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQI 1007
EHI +Y G D+ ++ + ME+ GSL G L A+ +
Sbjct 263 DCASEHICRYYGAFMDKSTGTISIAMEFCEGGSLDSIYKEVKKLGGRTGEKVLGKIAEGV 322
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV-- 1065
G+ YLH++ IHRD+ N+LL + VK+ DFG++ + + D ++ +
Sbjct 323 LNGLTYLHSRKIIHRDIKPSNILLCRNGQVKLCDFGVSGE-------FGTKGDANTFIGT 375
Query 1066 -FWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
++ APE + + SDVWS GVTL E+ H
Sbjct 376 SYYMAPERITGQSYTITSDVWSLGVTLLEVAQH 408
Score = 41.2 bits (95), Expect = 0.063, Method: Compositional matrix adjust.
Identities = 52/234 (22%), Positives = 96/234 (41%), Gaps = 44/234 (19%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+QK+I +L LG+G V +L+ +GK LK++
Sbjct 207 EQKKIIELGSLGEGAGGAVTRCKLK--------DGKT----------------VFALKII 242
Query 645 --DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEYVEHGPLDVWLR 700
DP + D+ + + H+ +G + + E+ E G LD +
Sbjct 243 TTDP-NPDVKKQIVRELNFNKDCASEHICRYYGAFMDKSTGTISIAMEFCEGGSLDSIYK 301
Query 701 RER---GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ G +A+ + + L+YL ++ ++H ++ NILL R G +KL
Sbjct 302 EVKKLGGRTGEKVLGKIAEGVLNGLTYLHSRKIIHRDIKPSNILLCRNGQ-------VKL 354
Query 758 SDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
D GV ++ + I ++APE + G + ++++ D W G TLLE+
Sbjct 355 CDFGVSGEFGTKGDANTFIGTSYYMAPERITGQSYTITS--DVWSLGVTLLEVA 406
>sp|C0LGN2|Y3148_ARATH Probable leucine-rich repeat receptor-like
serine/threonine-protein kinase At3g14840 OS=Arabidopsis
thaliana OX=3702 GN=LRR-RLK PE=1 SV=1
Length=1020
Score = 87.0 bits (214), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 81/241 (34%), Positives = 118/241 (49%), Gaps = 32/241 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG V DGT ++AVK L A +R + EI ++ L H H++K
Sbjct 678 IGEGGFGPVH---KGIMTDGT--VIAVKQLSAKSKQGNRE-FLNEIAMISALQHPHLVKL 731
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLL---FAQQIC----EGMAY 1013
GCC + + L LV EY+ SL L P+ + Q+ L Q+IC G+AY
Sbjct 732 YGCCVEGDQ--LLLVYEYLENNSLARALFGPQET----QIPLNWPMRQKICVGIARGLAY 785
Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
LH + +HRD+ A NVLLD + KI DFGLAK E + + R G + AP
Sbjct 786 LHEESRLKIVHRDIKATNVLLDKELNPKISDFGLAKLDEEENTHISTRVAG--TYGYMAP 843
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-----FLELIGIAQGQMTVLRLT 1125
E +DV+SFGV E++ H S+ S +K L+ + + + Q T+L +
Sbjct 844 EYAMRGHLTDKADVYSFGVVALEIV-HGKSNTSSRSKADTFYLLDWVHVLREQNTLLEVV 902
Query 1126 E 1126
+
Sbjct 903 D 903
Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 68/254 (27%), Positives = 115/254 (45%), Gaps = 46/254 (18%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAWKM- 712
F +++S + H HL ++G CV G + ++V EY+E+ L L + +P+ W M
Sbjct 713 FLNEIAMISALQHPHLVKLYGCCVEGDQLLLVYEYLENNSLARALFGPQETQIPLNWPMR 772
Query 713 -VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ +A L+YL ++ +VH ++ N+LL + +P K+SD GL L
Sbjct 773 QKICVGIARGLAYLHEESRLKIVHRDIKATNVLLDK-----ELNP--KISD--FGLAKLD 823
Query 769 REERV---ERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
EE R+ ++APE G L+ D + FG LEI G++ SRS +
Sbjct 824 EEENTHISTRVAGTYGYMAPEYAMRG--HLTDKADVYSFGVVALEIVH-GKSNTSSRSKA 880
Query 822 EK------EHFYQRQHRLPEPSCPQLATLTSQ------------CLTYEPTQRPSFRTIL 863
+ H + Q+ L E P+L T ++ C + P RPS T+
Sbjct 881 DTFYLLDWVHVLREQNTLLEVVDPRLGTDYNKQEALMMIQIGMLCTSPAPGDRPSMSTV- 939
Query 864 RDLTRLQPHNLADV 877
++ L+ H+ +V
Sbjct 940 --VSMLEGHSTVNV 951
>sp|Q9FG33|LRKS5_ARATH Probable L-type lectin-domain containing
receptor kinase S.5 OS=Arabidopsis thaliana OX=3702 GN=LECRKS5
PE=2 SV=1
Length=652
Score = 86.3 bits (212), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 71/237 (30%), Positives = 115/237 (49%), Gaps = 40/237 (17%)
Query 883 DSPASDPTVFHKRYLKKI-------RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935
D+ A++P F R LK+ LG+G FG V + G +AVK + ++
Sbjct 309 DNCAANPQKFKLRELKRATGNFGAENKLGQGGFGMVFKGKWQ------GRDIAVKRV-SE 361
Query 936 CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----- 990
Q + + EI + L H +++K G C ++ K LV EY+P GSL YL
Sbjct 362 KSHQGKQEFIAEITTIGNLNHRNLVKLLGWCYER--KEYLLVYEYMPNGSLDKYLFLEDK 419
Query 991 --------PRHSI--GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040
R +I GL+Q L + CE + +HRD+ A NV+LD+D K+G
Sbjct 420 SRSNLTWETRKNIITGLSQALEYLHNGCE-------KRILHRDIKASNVMLDSDFNAKLG 472
Query 1041 DFGLAKAVPEGH-EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
DFGLA+ + + ++ +E +P + APE + +DV++FGV + E+++
Sbjct 473 DFGLARMIQQSEMTHHSTKEIAGTPGY-MAPETFLNGRATVETDVYAFGVLMLEVVS 528
Score = 57.4 bits (137), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 62/274 (23%), Positives = 117/274 (43%), Gaps = 43/274 (16%)
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+ G+ +G+++ V K + H F + + ++H +L + G C E ++V
Sbjct 344 VFKGKWQGRDIAV--KRVSEKSHQGKQEFIAEITTIGNLNHRNLVKLLGWCYERKEYLLV 401
Query 687 TEYVEHGPLDVWL---RRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNI 740
EY+ +G LD +L + R ++ + + L+ AL YL N K ++H ++ N+
Sbjct 402 YEYMPNGSLDKYLFLEDKSRSNLTWETRKNIITGLSQALEYLHNGCEKRILHRDIKASNV 461
Query 741 LL-----ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAM 795
+L A+LG G + I+ S+ + S +E ++APE G ++ T
Sbjct 462 MLDSDFNAKLG-DFGLARMIQQSE----MTHHSTKEIAGTPGYMAPETFLNGRATVET-- 514
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ----------RQHRLPEPSCPQLATLT 845
D + FG +LE+ G+ P + ++ R + + + P + L
Sbjct 515 DVYAFGVLMLEVV-SGKKPSYVLVKDNQNNYNNSIVNWLWELYRNGTITDAADPGMGNLF 573
Query 846 SQ------------CLTYEPTQRPSFRTILRDLT 867
+ C P QRPS +T+L+ LT
Sbjct 574 DKEEMKSVLLLGLACCHPNPNQRPSMKTVLKVLT 607
>sp|Q54M77|ROCO8_DICDI Probable serine/threonine-protein kinase
roco8 OS=Dictyostelium discoideum OX=44689 GN=roco8 PE=3 SV=1
Length=1867
Score = 87.0 bits (214), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 69/244 (28%), Positives = 117/244 (48%), Gaps = 37/244 (15%)
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLA 998
+++E+ ++ L H +I+ KG C + +VMEY+ +GSL +L + +
Sbjct 1639 FRREVWLMSGLSHSNIVLMKGFCFE----PYAIVMEYMDIGSLSSFLKKKKEDGQVLDWQ 1694
Query 999 QLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD------NDRLVKIGDFGLAKAVPE 1050
LL I GMA+LH +HRDL + N+LL N+ K+ DFGL++++ +
Sbjct 1695 MLLKIVTDIASGMAFLHNITPPLVHRDLKSPNILLASHPTNPNEISAKVSDFGLSRSIVQ 1754
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
V D+P W +PE LK ++ SD++SFG+ L+E C + P +F +
Sbjct 1755 NFSSKVV----DNPT-WQSPEVLKGMEYNEKSDIYSFGMILWE----CYHLELPFDEF-D 1804
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
++ + +L G R C L+ CW + + RP+F + ILK
Sbjct 1805 FKFMSTLEDNIL-------SGLRPSINQNCNRMYSSLITKCWNADPNLRPSFNS---ILK 1854
Query 1171 TVHE 1174
T++E
Sbjct 1855 TLNE 1858
Score = 67.4 bits (163), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 65/226 (29%), Positives = 109/226 (48%), Gaps = 26/226 (12%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR--ERGHVPMAWKMV--VAQ 716
LMS +SH+++ + G C P I V EY++ G L +L++ E G V + W+M+ +
Sbjct 1645 LMSGLSHSNIVLMKGFCFE-PYAI-VMEYMDIGSLSSFLKKKKEDGQV-LDWQMLLKIVT 1701
Query 717 QLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSP---FIKLSDPGVGLGALSR-- 769
+AS +++L N LVH ++ NILLA + T+P K+SD G+ +
Sbjct 1702 DIASGMAFLHNITPPLVHRDLKSPNILLA----SHPTNPNEISAKVSDFGLSRSIVQNFS 1757
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATL-----LEICFDGEAPLQSRSPSEKE 824
+ V+ W +PE L G + D + FG L LE+ FD E + S E
Sbjct 1758 SKVVDNPTWQSPEVLKGME--YNEKSDIYSFGMILWECYHLELPFD-EFDFKFMSTLEDN 1814
Query 825 HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ + + ++L ++C +P RPSF +IL+ L ++
Sbjct 1815 ILSGLRPSINQNCNRMYSSLITKCWNADPNLRPSFNSILKTLNEIK 1860
>sp|O59790|ARK1_SCHPO Serine/threonine-protein kinase ark1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=ark1 PE=1 SV=2
Length=355
Score = 84.3 bits (207), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 66/220 (30%), Positives = 102/220 (46%), Gaps = 18/220 (8%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
P S FH + + LG+G FG+V Y TG +VA+K L Q +
Sbjct 74 PSSAGPQWREFHIGMFEIGKPLGKGKFGRV----YLAKEKKTGFIVALKTLHKSELVQSK 129
Query 942 --SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIG 996
++EI+I L H++I++ G D EK + L++E+ G L +L R S
Sbjct 130 IEKQVRREIEIQSNLRHKNILRLYGHFHD--EKRIYLILEFAGRGELYQHLRRAKRFSEE 187
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
+A +F Q+ ++YLH +H IHRD+ N+LL D +K+ DFG + P
Sbjct 188 VASKYIF--QMANALSYLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNR---- 241
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
R + + PE ++ + D+WS GV YE L
Sbjct 242 -RTTLCGTLDYLPPEMVEGKEHTEKVDLWSLGVLTYEFLV 280
Score = 52.4 bits (124), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 55/209 (26%), Positives = 92/209 (44%), Gaps = 17/209 (8%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLA 719
+ S + H ++ ++G ++ E+ G L LRR +R +A K + Q+A
Sbjct 140 IQSNLRHKNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIF--QMA 197
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--REERVERIP 777
+ALSYL K+++H ++ NILL G IKLSD G + A S R +
Sbjct 198 NALSYLHKKHVIHRDIKPENILL-------GIDGEIKLSDFGWSVHAPSNRRTTLCGTLD 250
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS--PSEKEHFYQRQHRLPE 835
+L PE + G + + +D W G E G P + S + + + ++P
Sbjct 251 YLPPEMVEGKEH--TEKVDLWSLGVLTYEFLV-GAPPFEDMSGHSATYKRIAKVDLKIPS 307
Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILR 864
P L S+ L + P +R S ++R
Sbjct 308 FVPPDARDLISRLLQHNPEKRMSLEQVMR 336
>sp|Q8AYC9|CHK1_CHICK Serine/threonine-protein kinase Chk1 OS=Gallus
gallus OX=9031 GN=CHEK1 PE=1 SV=1
Length=476
Score = 85.5 bits (210), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 70/200 (35%), Positives = 98/200 (49%), Gaps = 13/200 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
++ LGEG +G+V L N T E VAVK + K+EI I + L HE++
Sbjct 12 VQTLGEGAYGEVQL----AVNRRTEEAVAVKIVDMKRAADCPENIKKEICINKMLNHENV 67
Query 960 IKYKGCCEDQGEKSLQ-LVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+K+ G + E + Q L +EY G L D + P + + F QQ+ G+ YLH+
Sbjct 68 VKFYG---HRREGATQYLFLEYCSGGELFDRIEPDIGMPEPEAQRFFQQLIAGVVYLHSM 124
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEY 1076
HRDL N+LLD +KI DFGLA G E + G P + APE L+
Sbjct 125 GITHRDLKPENLLLDERDNLKISDFGLATVFKHNGRERLLNKMCGTLP--YVAPELLRRP 182
Query 1077 KFYYA-SDVWSFGVTLYELL 1095
+F DVW+ GV L +L
Sbjct 183 EFRAEPVDVWACGVVLTAML 202
>sp|Q39203|SD22_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase SD2-2 OS=Arabidopsis thaliana OX=3702
GN=SD22 PE=1 SV=1
Length=797
Score = 86.7 bits (213), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 65/199 (33%), Positives = 99/199 (50%), Gaps = 16/199 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + T G+ VAVK L+ + S ++ E+ + + H ++++
Sbjct 467 VGHGGFGAV----FKGTLPGSSTFVAVKRLERPGSGE--SEFRAEVCTIGNIQHVNLVRL 520
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL---LLFAQQICEGMAYLHA--- 1016
+G C + + LV +Y+P GSL YL R S L A +G+AYLH
Sbjct 521 RGFCSENLHR--LLVYDYMPQGSLSSYLSRTSPKLLSWETRFRIALGTAKGIAYLHEGCR 578
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IH D+ N+LLD+D K+ DFGLAK + G ++ RV + APE +
Sbjct 579 DCIIHCDIKPENILLDSDYNAKVSDFGLAKLL--GRDFSRVLATMRGTWGYVAPEWISGL 636
Query 1077 KFYYASDVWSFGVTLYELL 1095
+DV+SFG+TL EL+
Sbjct 637 PITTKADVYSFGMTLLELI 655
Score = 41.6 bits (96), Expect = 0.057, Method: Compositional matrix adjust.
Identities = 44/163 (27%), Positives = 72/163 (44%), Gaps = 20/163 (12%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F + + H +L + G C ++V +Y+ G L +L R + ++W +
Sbjct 502 FRAEVCTIGNIQHVNLVRLRGFCSENLHRLLVYDYMPQGSLSSYLSRTSPKL-LSWETRF 560
Query 713 VVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LG-A 766
+A A ++YL ++H ++ NILL A K+SD G+ LG
Sbjct 561 RIALGTAKGIAYLHEGCRDCIIHCDIKPENILLDSDYNA-------KVSDFGLAKLLGRD 613
Query 767 LSREERVERIPW--LAPECLPGGANSLSTAMDKWGFGATLLEI 807
SR R W +APE + G ++T D + FG TLLE+
Sbjct 614 FSRVLATMRGTWGYVAPEWISGLP--ITTKADVYSFGMTLLEL 654
>sp|Q9CAL2|CRK3_ARATH Cysteine-rich receptor-like protein kinase
3 OS=Arabidopsis thaliana OX=3702 GN=CRK3 PE=2 SV=1
Length=646
Score = 86.3 bits (212), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 70/208 (34%), Positives = 104/208 (50%), Gaps = 17/208 (8%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
Y LG+G G S+Y TN G+ VAVK L + Q + E++++ +
Sbjct 322 YFSDKNKLGQG--GSGSVYKGVLTN---GKTVAVKRLFFNT-KQWVDHFFNEVNLISQVD 375
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGM 1011
H++++K GC G +SL LV EY+ SL DYL + A+ EGM
Sbjct 376 HKNLVKLLGC-SITGPESL-LVYEYIANQSLHDYLFVRKDVQPLNWAKRFKIILGTAEGM 433
Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
AYLH + IHRD+ N+LL++D +I DFGLA+ PE + G + +
Sbjct 434 AYLHEESNLRIIHRDIKLSNILLEDDFTPRIADFGLARLFPEDKTHISTAIAG--TLGYM 491
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLT 1096
APE + K +DV+SFGV + E++T
Sbjct 492 APEYVVRGKLTEKADVYSFGVLMIEVIT 519
Score = 55.1 bits (131), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 43/163 (26%), Positives = 81/163 (50%), Gaps = 19/163 (12%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F+ +L+SQV H +L + G + GPE+++V EY+ + L +L + P+ W +
Sbjct 364 FFNEVNLISQVDHKNLVKLLGCSITGPESLLVYEYIANQSLHDYLFVRKDVQPLNWAKRF 423
Query 713 VVAQQLASALSYL-ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771
+ A ++YL E NL + R+I L+ + L + +P +++D GL L E+
Sbjct 424 KIILGTAEGMAYLHEESNL---RIIHRDIKLSNILLEDDFTP--RIAD--FGLARLFPED 476
Query 772 RVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+ + ++APE + G L+ D + FG ++E+
Sbjct 477 KTHISTAIAGTLGYMAPEYVVRG--KLTEKADVYSFGVLMIEV 517
>sp|P0CD62|LIMKB_DICDI Probable LIM domain-containing serine/threonine-protein
kinase DDB_G0286997 OS=Dictyostelium discoideum
OX=44689 GN=DDB_G0286997 PE=3 SV=1
Length=966
Score = 86.7 bits (213), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 73/276 (26%), Positives = 119/276 (43%), Gaps = 30/276 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH--II 960
+ G GKV Y G VA+K ++ + + +E+ I+ + +H
Sbjct 708 IAAGASGKVYKGIYK------GRDVAIKVYSSENFCFNIDEFDREVTIMSLIDSDHPNFT 761
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQH 1018
++ G Q +K L V E V GSLRD L L L A I M +LH+
Sbjct 762 RFYGA-NKQNKKYLFHVSELVKSGSLRDLLLDKEKPLLYFTQLSIASDIANAMKHLHSIG 820
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRDL + NVL+ D K+ DFG ++ V + G S + +PE K +
Sbjct 821 VIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLAK--HMTMNLGTS--CYMSPELFKGNGY 876
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
DV++FG+ L+E++ + ++ + + ++ +G+R P
Sbjct 877 DETCDVYAFGIVLWEIIARKEPYEN---------------INSWSIPVMVAKGDRPTIPA 921
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
CP E L+K CW + RP+F+ + LK + E
Sbjct 922 DCPSEYSKLIKACWTDKPKKRPSFKEICDTLKKISE 957
Score = 45.8 bits (107), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 55/228 (24%), Positives = 103/228 (45%), Gaps = 28/228 (12%)
Query 655 FYETASLMSQVSHTHLAFV--HGVCVRGPENIM-VTEYVEHGPL-DVWLRRERGHVPMAW 710
F ++MS + H F +G + + + V+E V+ G L D+ L +E+ P+ +
Sbjct 743 FDREVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSELVKSGSLRDLLLDKEK---PLLY 799
Query 711 --KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSD-PGVG 763
++ +A +A+A+ +L + ++H ++ N+L+ A+ GTS + L+ +
Sbjct 800 FTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLAKHMTMN 859
Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
LG +++PE G N D + FG L EI E P ++ +
Sbjct 860 LGTSC---------YMSPELFKG--NGYDETCDVYAFGIVLWEIIARKE-PYENINSWSI 907
Query 824 EHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ R P+ CP + + L C T +P +RPSF+ I L ++
Sbjct 908 PVMVAKGDRPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTLKKI 955
>sp|O80397|M2K4_ARATH Mitogen-activated protein kinase kinase
4 OS=Arabidopsis thaliana OX=3702 GN=MKK4 PE=1 SV=1
Length=366
Score = 84.3 bits (207), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 59/208 (28%), Positives = 107/208 (51%), Gaps = 19/208 (9%)
Query 894 KRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
K Y +R +G G G V + P++ + A+K + + R +EI+IL
Sbjct 74 KNYSDLVRGNRIGSGAGGTVYKVIHRPSS----RLYALKVIYGNHEETVRRQICREIEIL 129
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011
R + H +++K + GE +Q+++E++ GSL H QL ++QI G+
Sbjct 130 RDVNHPNVVKCHEMFDQNGE--IQVLLEFMDKGSLEGA---HVWKEQQLADLSRQILSGL 184
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
AYLH++H +HRD+ N+L+++ + VKI DFG+++ + + + + + +PE
Sbjct 185 AYLHSRHIVHRDIKPSNLLINSAKNVKIADFGVSRILAQTMDPC---NSSVGTIAYMSPE 241
Query 1072 ----CLKEYKFY-YASDVWSFGVTLYEL 1094
L + K+ YA D+WS GV++ E
Sbjct 242 RINTDLNQGKYDGYAGDIWSLGVSILEF 269
Score = 39.7 bits (91), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 50/240 (21%), Positives = 104/240 (43%), Gaps = 32/240 (13%)
Query 641 LKVLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD--- 696
LKV+ +H + + ++ V+H ++ H + + E ++ E+++ G L+
Sbjct 107 LKVIYGNHEETVRRQICREIEILRDVNHPNVVKCHEMFDQNGEIQVLLEFMDKGSLEGAH 166
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
VW ++ + ++Q+ S L+YL ++++VH ++ N+L+ ++ +K
Sbjct 167 VWKEQQLADL--------SRQILSGLAYLHSRHIVHRDIKPSNLLI-------NSAKNVK 211
Query 757 LSDPGVG-LGALSRE---ERVERIPWLAPECLPGGANSLS---TAMDKWGFGATLLEICF 809
++D GV + A + + V I +++PE + N A D W G ++LE +
Sbjct 212 IADFGVSRILAQTMDPCNSSVGTIAYMSPERINTDLNQGKYDGYAGDIWSLGVSILEF-Y 270
Query 810 DGEAPLQSRSPSEKEHF-----YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
G P + + P + P+ S CL EP +R S +L+
Sbjct 271 LGRFPFPVSRQGDWASLMCAICMSQPPEAPATASPEFRHFISCCLQREPGKRRSAMQLLQ 330
>sp|Q8TGI1|ATG1_PICPA Serine/threonine-protein kinase ATG1 OS=Komagataella
pastoris OX=4922 GN=ATG1 PE=3 SV=1
Length=796
Score = 86.7 bits (213), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 78/315 (25%), Positives = 133/315 (42%), Gaps = 67/315 (21%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959
++G G F V Y N T VA+K++ + + EI IL+ L H H+
Sbjct 14 EIGRGSFANV----YKGYNSKTQVSVAIKSVIKSRLRNKKLIENLEVEISILKNLKHPHV 69
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------------------PRHSIGL 997
+ C +Q + L+MEY LG L ++ P +S GL
Sbjct 70 VALLDC--EQSKHYFHLLMEYCSLGDLSYFITKREELISNHPLITGVFKKYPSPENSKGL 127
Query 998 AQLLL--FAQQICEGMAYLHAQHYIHRDLAARNVLLD--------NDR---------LVK 1038
+++ F QQ+ + +L +Q+ +HRD+ +N+LL DR ++K
Sbjct 128 NEVITINFVQQLASALKFLRSQNLVHRDIKPQNLLLSPPVSREVFEDRKYTGLWELPVLK 187
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
I DFG A+ +P + E + APE L+ K+ +D+WS G +YE+
Sbjct 188 IADFGFARFLPATS----MAETLCGSPLYMAPEILRYEKYNAKADLWSVGAVVYEM---- 239
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
S +PP A + +LR E + P+ + P E+ L+ + +A+
Sbjct 240 -SVGTPPFP-------AHNHVELLRNIERQKDKISFPKVAQVPPEIIQLICGLLKQQATE 291
Query 1159 RPTFENLI--PILKT 1171
R +F+ P++ T
Sbjct 292 RMSFQEFFNDPVITT 306
Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 60/206 (29%), Positives = 92/206 (45%), Gaps = 31/206 (15%)
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLA------------RLGLAEGTSPFIKLSDPGV 762
QQLASAL +L ++NLVH ++ +N+LL+ GL E P +K++D G
Sbjct 136 VQQLASALKFLRSQNLVHRDIKPQNLLLSPPVSREVFEDRKYTGLWE--LPVLKIADFGF 193
Query 763 G--LGALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
L A S E + P ++APE L + D W GA + E+ G P + +
Sbjct 194 ARFLPATSMAETLCGSPLYMAPEIL--RYEKYNAKADLWSVGAVVYEMSV-GTPPFPAHN 250
Query 820 PSEKEHFYQRQH-RLPEPSC----PQLATLTSQCLTYEPTQRPSFRTILRD---LTRLQP 871
E +RQ ++ P P++ L L + T+R SF+ D T+LQP
Sbjct 251 HVELLRNIERQKDKISFPKVAQVPPEIIQLICGLLKQQATERMSFQEFFNDPVITTKLQP 310
Query 872 HNLADVLTVNPDSPASDPTVFHKRYL 897
+ +L P + D +F YL
Sbjct 311 CSDEPLL---PQNQHIDENLFISEYL 333
>sp|Q8H1E3|PBL17_ARATH Probable serine/threonine-protein kinase
PBL17 OS=Arabidopsis thaliana OX=3702 GN=PBL17 PE=1 SV=1
Length=442
Score = 85.1 bits (209), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 79/240 (33%), Positives = 112/240 (47%), Gaps = 19/240 (8%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYL--KKIRD---LGEGHFGKVSLYCYDPTN--D 921
L P N+ D L NP D + + + K+ R LGEG FG V D +
Sbjct 58 LAPKNIKD-LQSNPGYENVDIFTYEEMKIATKQFRPDYILGEGGFGVVYKGVIDESVRVG 116
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG-CCEDQGEKSLQLVMEY 980
VA+K L + G Q W E++ L L H +++K G CCED LV EY
Sbjct 117 FKSTKVAIKELNPE-GFQGDREWLAEVNYLGQLSHPNLVKLIGYCCEDDHR---LLVYEY 172
Query 981 VPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHA--QHYIHRDLAARNVLLDNDR 1035
+ +GSL +L R ++ + + A +G+A+LH + I+RDL N+LLD
Sbjct 173 MAMGSLEKHLFRRVGCTLTWTKRMKIALDAAKGLAFLHGAERSIIYRDLKTANILLDEGY 232
Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
K+ DFGLAK P G + + V + APE + SDV+ FGV L E+L
Sbjct 233 NAKLSDFGLAKDGPRGDQTH-VSTRVMGTYGYAAPEYVMTGHLTSRSDVYGFGVLLLEML 291
Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 66/265 (25%), Positives = 113/265 (43%), Gaps = 40/265 (15%)
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+ +V +K L+P + + + Q+SH +L + G C ++V EY+ G
Sbjct 118 KSTKVAIKELNPEGFQGDREWLAEVNYLGQLSHPNLVKLIGYCCEDDHRLLVYEYMAMGS 177
Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHG---NVCGRNILLARLGLAE 749
L+ L R G + W +M +A A L++L HG ++ R++ A + L E
Sbjct 178 LEKHLFRRVG-CTLTWTKRMKIALDAAKGLAFL------HGAERSIIYRDLKTANILLDE 230
Query 750 GTSPFIKLSDPGVGL-GALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGAT 803
G + KLSD G+ G + V + APE + G L++ D +GFG
Sbjct 231 GYNA--KLSDFGLAKDGPRGDQTHVSTRVMGTYGYAAPEYVMTG--HLTSRSDVYGFGVL 286
Query 804 LLEICFDGEAPLQSRSPSEKE---------HFYQRQHRLPEP---------SCPQLATLT 845
LLE+ A +SR+ E + ++ R+ +P + ++A L
Sbjct 287 LLEMLLGKRAMDKSRACREHNLVEWARPLLNHNKKLLRIIDPRMDGQYGTKALMKVAGLA 346
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQ 870
QCL+ P RP ++ L L+
Sbjct 347 YQCLSQNPKGRPLMNHVVEVLETLK 371
>sp|Q8L4H4|NORK_MEDTR Nodulation receptor kinase OS=Medicago truncatula
OX=3880 GN=NORK PE=1 SV=2
Length=925
Score = 86.7 bits (213), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 78/278 (28%), Positives = 129/278 (46%), Gaps = 28/278 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG V Y T D G+ VAVK +++ Q + E+++L + HE+++
Sbjct 602 IGEGGFGSV----YRGTLDD-GQEVAVK-VRSSTSTQGTREFDNELNLLSAIQHENLVPL 655
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHA- 1016
G C + ++ L V ++ GSL D L R + L A G+AYLH
Sbjct 656 LGYCNEYDQQIL--VYPFMSNGSLLDRLYGEASKRKILDWPTRLSIALGAARGLAYLHTF 713
Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECL 1073
+ IHRD+ + N+LLD K+ DFG +K P EG Y + G + + PE
Sbjct 714 PGRSVIHRDVKSSNILLDQSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAG--YLDPEYY 771
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSP-----PTKFLELIGIAQGQMTVLRLTELL 1128
K + SDV+SFGV L E++ S + P P L+ A+ + ++ E++
Sbjct 772 KTQQLSEKSDVFSFGVVLLEIV----SGREPLNIKRPRIEWSLVEWAKPYIRASKVDEIV 827
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ G + + V + C E +++RP +++
Sbjct 828 DPGIKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIV 865
Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 88/381 (23%), Positives = 139/381 (36%), Gaps = 89/381 (23%)
Query 513 AFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPR 572
+ LEG+G+++P + +L + DD F ++ P
Sbjct 550 SITLEGFGKTYPMATNIIFSLP-----SKDDFF------------------IKSVSVKPF 586
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
TL ++Q + +G+G +VY G L D
Sbjct 587 TL-------EYIEQATEQYKTLIGEGGFGSVYRGTL-----------------------D 616
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
GQE V +KV + F +L+S + H +L + G C + I+V ++ +
Sbjct 617 DGQE--VAVKVRSSTSTQGTREFDNELNLLSAIQHENLVPLLGYCNEYDQQILVYPFMSN 674
Query 693 GPLDVWLRRERGHVP----MAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLA 743
G L L R G + W ++ +A A L+YL ++++H +V NILL
Sbjct 675 GSL---LDRLYGEASKRKILDWPTRLSIALGAARGLAYLHTFPGRSVIHRDVKSSNILLD 731
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+ A+ P G +S E R +L PE LS D + FG
Sbjct 732 QSMCAKVADFGFSKYAPQEGDSYVSLEVR-GTAGYLDPEYYK--TQQLSEKSDVFSFGVV 788
Query 804 LLEICFDGEAPLQSRSPS------EKEHFYQRQHRLPEPSCP------------QLATLT 845
LLEI G PL + P E Y R ++ E P ++ +
Sbjct 789 LLEIV-SGREPLNIKRPRIEWSLVEWAKPYIRASKVDEIVDPGIKGGYHAEALWRVVEVA 847
Query 846 SQCLTYEPTQRPSFRTILRDL 866
QCL T RP I+R+L
Sbjct 848 LQCLEPYSTYRPCMVDIVREL 868
>sp|Q9R011|PLK3_RAT Serine/threonine-protein kinase PLK3 OS=Rattus
norvegicus OX=10116 GN=Plk3 PE=1 SV=2
Length=647
Score = 86.3 bits (212), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 69/231 (30%), Positives = 108/231 (47%), Gaps = 14/231 (6%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
R +P LA T + +DP R K R LG+G F + CY+ T+ T
Sbjct 35 RSEPGVLAGPQTPDASRLITDPR--SGRTYIKGRLLGKGGFAR----CYEATDTETSIAY 88
Query 928 AVKALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
AVK + P R EI++ R L H HI+++ ED ++ + +E S
Sbjct 89 AVKVIPQSRVAKPHQREKIINEIELHRDLQHRHIVRFSHHFEDA--DNIYIFLELCSRKS 146
Query 986 LRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
L + RH++ ++ + +QI G+ YLH + +HRDL N + ++ +K+GDFGL
Sbjct 147 LAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGL 206
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
A + + R + +P + APE L +DVWS G +Y LL
Sbjct 207 AARLEPPEQ--RKKTICGTPNY-VAPEVLLRQGHGPEADVWSLGCVMYTLL 254
>sp|C0LGR6|Y4291_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At4g29180 OS=Arabidopsis thaliana OX=3702
GN=At4g29180 PE=1 SV=2
Length=913
Score = 86.7 bits (213), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 65/212 (31%), Positives = 106/212 (50%), Gaps = 26/212 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK------------ADCGPQHRSGWKQEIDI 950
+G+G FG V L + DGT +AVK + + Q ++ E ++
Sbjct 573 IGKGGFGIVYLGSLE---DGT--EIAVKMINDSSFGKSKGSSSSSSSSQVSKEFQVEAEL 627
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQI 1007
L T++H ++ + G C+D +S+ L+ EY+ G+L+DYL + + + L A
Sbjct 628 LLTVHHRNLASFVGYCDDG--RSMALIYEYMANGNLQDYLSSENAEDLSWEKRLHIAIDS 685
Query 1008 CEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+G+ YLH +HRD+ N+LL+++ KI DFGL+K PE + V +P
Sbjct 686 AQGLEYLHHGCRPPIVHRDVKTANILLNDNLEAKIADFGLSKVFPEDDLSHVVTAVMGTP 745
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+ PE +K SDV+SFG+ L EL+T
Sbjct 746 GY-VDPEYYNTFKLNEKSDVYSFGIVLLELIT 776
Score = 39.3 bits (90), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 67/278 (24%), Positives = 106/278 (38%), Gaps = 46/278 (17%)
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
++ F A L+ V H +LA G C G ++ EY+ +G L +L E ++W
Sbjct 617 VSKEFQVEAELLLTVHHRNLASFVGYCDDGRSMALIYEYMANGNLQDYLSSENAE-DLSW 675
Query 711 --KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
++ +A A L YL + +VH +V NILL A K++D GL
Sbjct 676 EKRLHIAIDSAQGLEYLHHGCRPPIVHRDVKTANILLNDNLEA-------KIAD--FGLS 726
Query 766 ALSREERVERIPWLAPECLPGGAN-------SLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ E+ + + A PG + L+ D + FG LLE+ G+ +
Sbjct 727 KVFPEDDLSHVV-TAVMGTPGYVDPEYYNTFKLNEKSDVYSFGIVLLEL-ITGKRSIMKT 784
Query 819 SPSEKE---HFYQ--------------RQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
EK H+ + R H S + + C+ T RP+
Sbjct 785 DDGEKMNVVHYVEPFLKMGDIDGVVDPRLHGDFSSNSAWKFVEVAMSCVRDRGTNRPNTN 844
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898
I+ DL + LA L P S V ++Y K
Sbjct 845 QIVSDLKQC----LAAELAREPKSNHEKKEVVKEKYTK 878
>sp|Q5R495|OXSR1_PONAB Serine/threonine-protein kinase OSR1 OS=Pongo
abelii OX=9601 GN=OXSR1 PE=2 SV=1
Length=527
Score = 85.5 bits (210), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 61/200 (31%), Positives = 98/200 (49%), Gaps = 15/200 (8%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
E VA+K + + +EI + +H +I+ Y + E L LVM+ + G
Sbjct 41 EKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGG 98
Query 985 SLRDYLP------RHSIGL---AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035
S+ D + H G+ + + +++ EG+ YLH IHRD+ A N+LL D
Sbjct 99 SVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG 158
Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092
V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T
Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAI 218
Query 1093 ELLTHCDS-SQSPPTKFLEL 1111
EL T + PP K L L
Sbjct 219 ELATGAAPYHKYPPMKVLML 238
Score = 37.7 bits (86), Expect = 0.71, Method: Compositional matrix adjust.
Identities = 42/169 (25%), Positives = 66/169 (39%), Gaps = 23/169 (14%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALS 768
+ +++ L YL +H +V NILL G + G S F L+ G
Sbjct 125 TILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAF--LATGGDITRNKV 182
Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------L 815
R+ V W+APE + D W FG T +E+ G AP L
Sbjct 183 RKTFVGTPCWMAPEVME-QVRGYDFKADIWSFGITAIELA-TGAAPYHKYPPMKVLMLTL 240
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
Q+ PS + ++ + + + S CL +P +RP+ +LR
Sbjct 241 QNDPPSLETGVQDKE--MLKKYGKSFRKMISLCLQKDPEKRPTAAELLR 287
>sp|O95747|OXSR1_HUMAN Serine/threonine-protein kinase OSR1 OS=Homo
sapiens OX=9606 GN=OXSR1 PE=1 SV=1
Length=527
Score = 85.5 bits (210), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 61/200 (31%), Positives = 98/200 (49%), Gaps = 15/200 (8%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
E VA+K + + +EI + +H +I+ Y + E L LVM+ + G
Sbjct 41 EKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGG 98
Query 985 SLRDYLP------RHSIGL---AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035
S+ D + H G+ + + +++ EG+ YLH IHRD+ A N+LL D
Sbjct 99 SVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG 158
Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092
V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T
Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAI 218
Query 1093 ELLTHCDS-SQSPPTKFLEL 1111
EL T + PP K L L
Sbjct 219 ELATGAAPYHKYPPMKVLML 238
Score = 37.7 bits (86), Expect = 0.75, Method: Compositional matrix adjust.
Identities = 42/169 (25%), Positives = 66/169 (39%), Gaps = 23/169 (14%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALS 768
+ +++ L YL +H +V NILL G + G S F L+ G
Sbjct 125 TILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAF--LATGGDITRNKV 182
Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------L 815
R+ V W+APE + D W FG T +E+ G AP L
Sbjct 183 RKTFVGTPCWMAPEVME-QVRGYDFKADIWSFGITAIELA-TGAAPYHKYPPMKVLMLTL 240
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
Q+ PS + ++ + + + S CL +P +RP+ +LR
Sbjct 241 QNDPPSLETGVQDKE--MLKKYGKSFRKMISLCLQKDPEKRPTAAELLR 287
>sp|C0LGU5|Y5457_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At5g45780 OS=Arabidopsis thaliana OX=3702
GN=At5g45780 PE=1 SV=1
Length=614
Score = 85.9 bits (211), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 84/296 (28%), Positives = 134/296 (45%), Gaps = 26/296 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V Y P G +VAVK LK D ++ E++++ H ++++
Sbjct 306 LGQGGFGMV-YKGYLPN----GTVVAVKRLK-DPIYTGEVQFQTEVEMIGLAVHRNLLRL 359
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRD-----YLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
G C E+ LV Y+P GS+ D Y + S+ + + A G+ YLH Q
Sbjct 360 FGFCMTPEER--MLVYPYMPNGSVADRLRDNYGEKPSLDWNRRISIALGAARGLVYLHEQ 417
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRD+ A N+LLD +GDFGLAK + + + G + APE L
Sbjct 418 CNPKIIHRDVKAANILLDESFEAIVGDFGLAKLLDQRDSHVTTAVRG--TIGHIAPEYLS 475
Query 1075 EYKFYYASDVWSFGVTLYELLT---HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ +DV+ FGV + EL+T D K + ++ + R E+++R
Sbjct 476 TGQSSEKTDVFGFGVLILELITGHKMIDQGNGQVRKGM-ILSWVRTLKAEKRFAEMVDRD 534
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK----YQGQAPSV 1183
+ D EV L C + + RP ++ +L+ + E+ Y+ +APSV
Sbjct 535 LKGEFDDLVLEEVVELALLCTQPHPNLRPRMSQVLKVLEGLVEQCEGGYEARAPSV 590
>sp|Q924X7|STK33_MOUSE Serine/threonine-protein kinase 33 OS=Mus
musculus OX=10090 GN=Stk33 PE=1 SV=2
Length=491
Score = 85.5 bits (210), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 58/206 (28%), Positives = 99/206 (48%), Gaps = 18/206 (9%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
R LG+G FG V ++ + TG A+K + K G ++E+ IL+T+ H+HI
Sbjct 115 RILGQGSFGMV----FEAIDKETGAKWAIKKVNKEKAGSSAMKLLEREVSILKTVNHQHI 170
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I + E + + LVME G L+ + R + L Q + +AYLH +
Sbjct 171 IHLEQVFE--SPQKMYLVMELCEDGELKAVMDQRGHFSENETRLIIQSLASAIAYLHNKD 228
Query 1019 YIHRDLAARNVLL------DNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+HRDL N+++ DN+ + +K+ DFGL+ ++ +P++ A
Sbjct 229 IVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPIY-MA 287
Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095
PE + + + D+WS GV ++ LL
Sbjct 288 PEVINAHDYSQQCDIWSIGVIMFILL 313
Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 57/248 (23%), Positives = 105/248 (42%), Gaps = 24/248 (10%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S++ V+H H+ + V + +V E E G L + +RGH ++ Q LA
Sbjct 160 SILKTVNHQHIIHLEQVFESPQKMYLVMELCEDGELKAVMD-QRGHFSENETRLIIQSLA 218
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777
SA++YL NK++VH ++ NI++ + + + + GL R E +
Sbjct 219 SAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQT 278
Query 778 ------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-Q 830
++APE + A+ S D W G + I GE P + S + ++ +
Sbjct 279 TCGTPIYMAPEVI--NAHDYSQQCDIWSIGVIMF-ILLCGEPPFLANSEEKLYELIKKGE 335
Query 831 HRLPEP---SCPQLATLT-SQCLTYEPTQRPSFRTILRD-------LTRLQPHNLADVLT 879
R P S A T Q + +P R + + +L + L+ +P N+ +++
Sbjct 336 LRFENPVWESVSDSAKNTLKQLMKVDPAHRITAKELLDNQWLTGNTLSSARPTNVLEMMK 395
Query 880 VNPDSPAS 887
++P S
Sbjct 396 EWKNNPES 403
>sp|Q0D5R3|CRK6_ORYSJ Cysteine-rich receptor-like protein kinase
6 OS=Oryza sativa subsp. japonica OX=39947 GN=CRK6 PE=1 SV=1
Length=695
Score = 86.3 bits (212), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 81/279 (29%), Positives = 128/279 (46%), Gaps = 21/279 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FG V G+ +AVK L Q K E+ ++ LYH+++++
Sbjct 369 IGQGGFGMVYKGVLP-----DGQEIAVKRL-CQSSRQGIGELKSELILVAKLYHKNLVRL 422
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLR----DYLPRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017
G C +Q EK L V EY+P GSL D + + I G+ YLH
Sbjct 423 IGVCLEQQEKIL--VYEYMPNGSLDIVLFDTDKNRELDWGKRFKIINGIARGLQYLHEDS 480
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRDL A N+LLD D KI DFGLAK + G + V + APE
Sbjct 481 QLKIVHRDLKASNILLDFDYSPKISDFGLAK-IFGGDQSEDVTNRIAGTYGYMAPEYAMR 539
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLRLTELLE--RGE 1132
+ SDV+SFGV + E++T ++ S + + ++L+ + T + EL++ G+
Sbjct 540 GNYSIKSDVFSFGVLVLEIITGRRNTGSYDSGQDVDLLNLVWEHWTRGNVVELIDPSMGD 599
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
P C H+ C + + + RPT ++ +L +
Sbjct 600 HPPIEQMLKC--IHIGLLCVQKKPASRPTISSVNIMLSS 636
Score = 53.1 bits (126), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 47/158 (30%), Positives = 76/158 (48%), Gaps = 20/158 (13%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQL 718
L++++ H +L + GVC+ E I+V EY+ +G LD+ L + + W + + +
Sbjct 410 LVAKLYHKNLVRLIGVCLEQQEKILVYEYMPNGSLDIVLFDTDKNRELDWGKRFKIINGI 469
Query 719 ASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERV 773
A L YL + +VH ++ NILL SP K+SD G+ G E+
Sbjct 470 ARGLQYLHEDSQLKIVHRDLKASNILLDF-----DYSP--KISDFGLAKIFGGDQSEDVT 522
Query 774 ERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
RI ++APE G S+ + D + FG +LEI
Sbjct 523 NRIAGTYGYMAPEYAMRGNYSIKS--DVFSFGVLVLEI 558
>sp|Q65X23|WNK2_ORYSJ Probable serine/threonine-protein kinase
WNK2 OS=Oryza sativa subsp. japonica OX=39947 GN=WNK2 PE=2
SV=1
Length=621
Score = 85.9 bits (211), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 72/241 (30%), Positives = 117/241 (49%), Gaps = 27/241 (11%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935
D+L P+ DPT + RY + LG+G F V Y + G VA +K
Sbjct 10 DLLDTEPEFAEVDPTARYGRYTEV---LGKGAFKTV----YKAFDQLEGLEVAWNQIK-- 60
Query 936 CGPQHRSG-----WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
G R+ + E+ +L+TL H++IIK+ D+ ++ + E G+LR Y
Sbjct 61 VGDILRNNDDLERLRSEVRLLKTLKHKNIIKFYNSWLDKKNNNINFITEVFTSGTLRQYR 120
Query 991 PRH-SIGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFGLAK 1046
+H + + L +++QI G+ YLH+ IHRDL N+ ++ N VKIGD GLA
Sbjct 121 IKHKKVDVRALKKWSRQILSGLVYLHSHDPPVIHRDLKCDNIFVNGNQGEVKIGDLGLAT 180
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT----HCDSSQ 1102
+ + + +P F APE E ++ D+++FG+ L EL+T +C+ S
Sbjct 181 ILDNARSAHSII---GTPEFM-APELYDE-EYNELVDIYAFGMCLLELVTFEYPYCECSN 235
Query 1103 S 1103
+
Sbjct 236 A 236
>sp|Q755C4|IPL1_EREGS Spindle assembly checkpoint kinase OS=Eremothecium
gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923
/ NRRL Y-1056) OX=284811 GN=IPL1 PE=3 SV=1
Length=367
Score = 84.0 bits (206), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 69/260 (27%), Positives = 122/260 (47%), Gaps = 29/260 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHII 960
LG+G FG+V YC +G + A+KA++ Q+ +++E++I +L H ++
Sbjct 115 LGKGKFGRV--YCVRHIE--SGFVCALKAMEKKDIIQYNIEKQFRREVEIQSSLRHPNLT 170
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G D EK + L+MEY+ G L +L R + Q+ + + Y+H ++
Sbjct 171 QLYGYFHD--EKRVYLLMEYLVNGELYKHLKGRSHFNDVVASYYVYQMADALDYMHERNI 228
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRD+ N+++ + +K+ DFG + P+G + R+ V + +PE ++ ++
Sbjct 229 LHRDIKPENIIIGFNNTIKLTDFGWSVITPKGSK----RKTLCGTVDYLSPELIRSREYN 284
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
DVW+ GV YELL SPP + + L +L+R L PD
Sbjct 285 EKVDVWALGVLTYELLV-----GSPP---------FEEESKELTYKRILKRN--LIFPDH 328
Query 1140 CPCEVYHLMKNCWETEASFR 1159
E HL+ E + R
Sbjct 329 VDTEARHLISRLLEYDPGDR 348
Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 51/225 (23%), Positives = 93/225 (41%), Gaps = 21/225 (9%)
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D ++I F + S + H +L ++G ++ EY+ +G L L+ R
Sbjct 144 DIIQYNIEKQFRREVEIQSSLRHPNLTQLYGYFHDEKRVYLLMEYLVNGELYKHLK-GRS 202
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG--- 761
H Q+A AL Y+ +N++H ++ NI++ G + IKL+D G
Sbjct 203 HFNDVVASYYVYQMADALDYMHERNILHRDIKPENIII-------GFNNTIKLTDFGWSV 255
Query 762 VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ R+ + +L+PE + + + +D W G E+ G P + S
Sbjct 256 ITPKGSKRKTLCGTVDYLSPELI--RSREYNEKVDVWALGVLTYELLV-GSPPFEEES-- 310
Query 822 EKEHFYQRQHR----LPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
KE Y+R + P+ + L S+ L Y+P R + +
Sbjct 311 -KELTYKRILKRNLIFPDHVDTEARHLISRLLEYDPGDRIPLKEV 354
>sp|Q59W62|GIN4_CANAL Serine/threonine-protein kinase GIN4 OS=Candida
albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=GIN4
PE=1 SV=1
Length=1349
Score = 86.7 bits (213), Expect = 9e-16, Method: Compositional matrix adjust.
Identities = 71/207 (34%), Positives = 105/207 (51%), Gaps = 21/207 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRS--------GWKQEIDIL 951
+ LG G G+V L T+ TG+ AVK + K++ + G ++EI I+
Sbjct 32 KTLGRGATGRVLL----ATHQTTGQKAAVKVVSKSELQDEETEKNGDGLPYGIEREIIIM 87
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEG 1010
+ L H ++++ E K+L LV+EYV G L D L R + + + + +QI G
Sbjct 88 KLLTHPNVLRLYDVWE--TSKALYLVLEYVEGGELFDLLVERGPLPEVEAIKYFRQIILG 145
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
AY HA HRDL N+LLD+ VK+ DFG+A G ++ E + AP
Sbjct 146 TAYCHALGICHRDLKPENLLLDSQLNVKLADFGMAALESNG----KLLETSCGSPHYAAP 201
Query 1071 ECLKEYKFY-YASDVWSFGVTLYELLT 1096
E + K++ ASDVWS GV L+ LLT
Sbjct 202 EIVSGLKYHGAASDVWSCGVILFALLT 228
>sp|Q9SIB6|PBL6_ARATH Probable serine/threonine-protein kinase
PBL6 OS=Arabidopsis thaliana OX=3702 GN=PBL6 PE=2 SV=1
Length=424
Score = 84.7 bits (208), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 69/202 (34%), Positives = 100/202 (50%), Gaps = 16/202 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FGKV Y + ++VA+K L + G Q + E+ L H +++K
Sbjct 104 LGEGGFGKV----YKGFIEKINQVVAIKQLDRN-GAQGIREFVVEVLTLSLADHPNLVKL 158
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
G C +G + L LV EY+PLGSL ++L ++ + + A G+ YLH
Sbjct 159 IGFCA-EGVQRL-LVYEYMPLGSLDNHLHDLPSGKNPLAWNTRMKIAAGAARGLEYLHDT 216
Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
I+RDL N+L+D K+ DFGLAK P G E + V + AP+
Sbjct 217 MKPPVIYRDLKCSNILIDEGYHAKLSDFGLAKVGPRGSETH-VSTRVMGTYGYCAPDYAL 275
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ + SDV+SFGV L EL+T
Sbjct 276 TGQLTFKSDVYSFGVVLLELIT 297
Score = 50.4 bits (119), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 64/256 (25%), Positives = 105/256 (41%), Gaps = 29/256 (11%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K LD + F +S H +L + G C G + ++V EY+ G LD
Sbjct 124 VAIKQLDRNGAQGIREFVVEVLTLSLADHPNLVKLIGFCAEGVQRLLVYEYMPLGSLDNH 183
Query 699 LRR-ERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
L G P+AW +M +A A L YL + + V R++ + + + EG
Sbjct 184 LHDLPSGKNPLAWNTRMKIAAGAARGLEYLH--DTMKPPVIYRDLKCSNILIDEGYHA-- 239
Query 756 KLSDPGVG-LGALSREERVE-RIPWLAPECLPGGA--NSLSTAMDKWGFGATLLEICFDG 811
KLSD G+ +G E V R+ C P A L+ D + FG LLE+
Sbjct 240 KLSDFGLAKVGPRGSETHVSTRVMGTYGYCAPDYALTGQLTFKSDVYSFGVVLLELITGR 299
Query 812 EAPLQSRSPS-------------EKEHFYQRQHRLPEPSCP-----QLATLTSQCLTYEP 853
+A +R+ + ++++F + L E P Q + + C+ +P
Sbjct 300 KAYDNTRTRNHQSLVEWANPLFKDRKNFKKMVDPLLEGDYPVRGLYQALAIAAMCVQEQP 359
Query 854 TQRPSFRTILRDLTRL 869
+ RP ++ L L
Sbjct 360 SMRPVIADVVMALDHL 375
>sp|Q9SEZ7|CIPKG_ARATH CBL-interacting serine/threonine-protein
kinase 16 OS=Arabidopsis thaliana OX=3702 GN=CIPK16 PE=1 SV=1
Length=469
Score = 85.1 bits (209), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 72/226 (32%), Positives = 114/226 (50%), Gaps = 23/226 (10%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
+S S +F K + ++ LG G+F KV Y T TG+ VA+K +K D + R
Sbjct 3 ESNRSSTVLFDKYNIGRL--LGTGNFAKV----YHGTEISTGDDVAIKVIKKDHVFKRRG 56
Query 943 GWKQ---EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ 999
+Q EI ++R L H ++++ + +K + VMEYV G L + + R L +
Sbjct 57 MMEQIEREIAVMRLLRHPNVVELREVM--ATKKKIFFVMEYVNGGELFEMIDRDG-KLPE 113
Query 1000 LLL--FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYR 1056
L + QQ+ + + H++ HRD+ N+LLD + +K+ DFGL A +PEG R
Sbjct 114 DLARKYFQQLISAVDFCHSRGVFHRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRR 173
Query 1057 VREDG------DSPVFWYAPECLKEYKFYYA-SDVWSFGVTLYELL 1095
D +P + APE L+ + A +D+WS G+ LY LL
Sbjct 174 GSSDDLLHTRCGTPA-YVAPEVLRNKGYDGAMADIWSCGIVLYALL 218
>sp|Q869W6|MYLKG_DICDI Probable myosin light chain kinase DDB_G0275057
OS=Dictyostelium discoideum OX=44689 GN=DDB_G0275057
PE=3 SV=1
Length=349
Score = 83.6 bits (205), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 66/200 (33%), Positives = 94/200 (47%), Gaps = 15/200 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
++LG G F V + T T + VA+K + K +H ++EIDI++ + HE++
Sbjct 60 KELGRGAFSVVR----EGTRKTTSDKVALKYIEKKFVKKKHIEQLRREIDIMKKVKHENV 115
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ K E + L LVME V G L + R S +Q+C G+ YLH+Q
Sbjct 116 LSLKEIFE--SDSHLTLVMELVTGGELFYKIVERGSFTEKGARNVVRQVCAGVEYLHSQG 173
Query 1019 YIHRDLAARNVLLDN---DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
HRDL N+L + D +KI DFGL+K G E + APE L
Sbjct 174 IAHRDLKPENLLCNGEGEDMTIKIADFGLSKIFGTG----EALETSCGTPDYVAPEVLTG 229
Query 1076 YKFYYASDVWSFGVTLYELL 1095
+ A D+WS GV Y LL
Sbjct 230 GSYDNAVDMWSIGVITYILL 249
Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 53/216 (25%), Positives = 89/216 (41%), Gaps = 20/216 (9%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
+M +V H ++ + + +V E V G L + ERG V +Q+ +
Sbjct 106 IMKKVKHENVLSLKEIFESDSHLTLVMELVTGGEL-FYKIVERGSFTEKGARNVVRQVCA 164
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREERVERI 776
+ YL ++ + H ++ N+L EG IK++D G+ G G + E
Sbjct 165 GVEYLHSQGIAHRDLKPENLLCN----GEGEDMTIKIADFGLSKIFGTGE-ALETSCGTP 219
Query 777 PWLAPECLPGGANSLSTAMDKWGFGA-TLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLP 834
++APE L GG S A+D W G T + +C G P + S + E + P
Sbjct 220 DYVAPEVLTGG--SYDNAVDMWSIGVITYILLC--GFPPFYASSQNLLFEKILTADYDFP 275
Query 835 EPSCPQLA----TLTSQCLTYEPTQRPSFRTILRDL 866
EP ++ + +P QR + + L DL
Sbjct 276 EPEWTHVSEHAKAFIRNLIVKDPDQRHTAKQCLDDL 311
>sp|A2VDU3|M3K7_BOVIN Mitogen-activated protein kinase kinase
kinase 7 OS=Bos taurus OX=9913 GN=MAP3K7 PE=2 SV=1
Length=579
Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 78/275 (28%), Positives = 124/275 (45%), Gaps = 40/275 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + + VA+K ++++ R + E+ L + H +I+K
Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
G C + + LVMEY GSL + L P A + + Q +G+AYLH+
Sbjct 93 YGACLN----PVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148
Query 1019 ---YIHRDLAARNVLL-DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL N+LL ++KI DFG A + + + G + W APE +
Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTACDI----QTHMTNNKGSAA--WMAPEVFE 202
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ DV+S+G+ L+E++T + P F E+ G A R+ + G R
Sbjct 203 GSNYSEKCDVFSWGIILWEVITR----RKP---FDEIGGPA------FRIMWAVHNGTRP 249
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P P + LM CW + S RP+ E ++ I+
Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIM 284
Score = 43.9 bits (102), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 57/233 (24%), Positives = 103/233 (44%), Gaps = 35/233 (15%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------ 707
AF +S+V+H ++ ++G C+ +V EY E G L L G P
Sbjct 73 AFIVELRQLSRVNHPNIVKLYGACLNPV--CLVMEYAEGGSLYNVLH---GAEPLPYYTA 127
Query 708 ---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
M+W + +Q +A L ++ K L+H ++ N+LL +A GT +K+ D G
Sbjct 128 AHAMSWCLQCSQGVA-YLHSMQPKALIHRDLKPPNLLL----VAGGT--VLKICDFGTAC 180
Query 765 GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ + W+APE G ++ S D + +G L E+ + + P+ +
Sbjct 181 DIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFR 238
Query 824 EHFYQRQ-------HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ LP+P + +L ++C + +P+QRPS I++ +T L
Sbjct 239 IMWAVHNGTRPPLIKNLPKP----IESLMTRCWSKDPSQRPSMEEIVKIMTHL 287
>sp|P22216|RAD53_YEAST Serine/threonine-protein kinase RAD53 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=RAD53 PE=1 SV=1
Length=821
Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 83/300 (28%), Positives = 138/300 (46%), Gaps = 35/300 (12%)
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906
QCL R R+ L++ +++ L + S ++ T K + +G+G
Sbjct 153 QCLEQNKVDR--IRSNLKNTSKIASPGLT---SSTASSMVANKTGIFKDFSIIDEVVGQG 207
Query 907 HFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC 966
F V TG+ AVK + + G +E+++L+ L H I++ KG
Sbjct 208 AFATVK----KAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFY 263
Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
ED +S +VME+V G L D++ H ++G ++QI + Y+H+ HRDL
Sbjct 264 ED--TESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLK 321
Query 1026 ARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK--------- 1074
N+L++ D LVKI DFGLAK +G+ + G + + APE ++
Sbjct 322 PDNILIEQDDPVLVKITDFGLAKV--QGNGSFMKTFCG--TLAYVAPEVIRGKDTSVSPD 377
Query 1075 --EYKFYYAS--DVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIA---QGQMTVLRLTE 1126
E + Y+S D+WS G +Y +LT H S S + + IG +G + R++E
Sbjct 378 EYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISE 437
>sp|Q06309|CRK1_LEIME Cell division protein kinase 2 homolog CRK1
OS=Leishmania mexicana OX=5665 GN=CRK1 PE=2 SV=1
Length=301
Score = 82.8 bits (203), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 64/202 (32%), Positives = 101/202 (50%), Gaps = 22/202 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIK 961
+GEG +G V Y + T VA+K ++ D + +EI +L+ L HE+I+K
Sbjct 11 IGEGTYGVV----YKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRHENIVK 66
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHY 1019
C E L +V EY+ L L+ YL R + L A + F + + G+A+ H +
Sbjct 67 LLDVC--HSEHRLTIVFEYLDL-DLKKYLDRENGNLDAATIQHFMRDLLRGVAFCHQRSV 123
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAK--AVPEGHEYYRVREDGDSPV-FWYAPE--CLK 1074
+HRDL +N+L+ ++ +K+GDFGL + A+P VR+ + V WY P L
Sbjct 124 LHRDLKPQNLLISREKELKLGDFGLGRSFAIP-------VRKFTNEVVTLWYRPPDVLLG 176
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
++ DVWS G E+ T
Sbjct 177 SMQYGPPVDVWSVGCIFSEMAT 198
Score = 36.6 bits (83), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 40/184 (22%), Positives = 75/184 (41%), Gaps = 13/184 (7%)
Query 630 GRDRGQELRVVLKV--LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
RD V LK LD + SL+ ++ H ++ + VC +V
Sbjct 22 ARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRHENIVKLLDVCHSEHRLTIVF 81
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
EY++ L +L RE G++ A + L +++ ++++H ++ +N+L++R
Sbjct 82 EYLDLD-LKKYLDRENGNLDAATIQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISR--- 137
Query 748 AEGTSPFIKLSDPGVG--LGALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATL 804
+KL D G+G R+ E + W P + G+ +D W G
Sbjct 138 ----EKELKLGDFGLGRSFAIPVRKFTNEVVTLWYRPPDVLLGSMQYGPPVDVWSVGCIF 193
Query 805 LEIC 808
E+
Sbjct 194 SEMA 197
>sp|O22834|LRK53_ARATH Probable L-type lectin-domain containing
receptor kinase V.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK53
PE=3 SV=1
Length=664
Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 77/283 (27%), Positives = 124/283 (44%), Gaps = 23/283 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG V + T G+ +AVK + D R EI + L H ++++
Sbjct 341 LGEGGFGPV----FKGTLSGSNAKIAVKRVSHDSSQGMRE-LLAEISTIGRLRHPNLVRL 395
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH--- 1015
G C + E L LV +++P GSL YL + + +Q + + ++YLH
Sbjct 396 LGYCRYKEE--LYLVYDFLPNGSLDKYLYGTSDQKQLSWSQRFKIIKDVASALSYLHHGW 453
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074
IHRD+ NVL+D+ +GDFGLAK +G++ R G F Y APE ++
Sbjct 454 IHVVIHRDIKPANVLIDDKMNASLGDFGLAKVYDQGYDPQTSRVAG---TFGYMAPEIMR 510
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ +DV++FG+ + E+ CD P E + + +++E
Sbjct 511 TGRPTMGTDVYAFGMFMLEV--SCDRKLFEPRAESEEAILTNWAINCWENGDIVEAATER 568
Query 1135 PRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILKTVHE 1174
R D ++ ++K C RP ++ IL V E
Sbjct 569 IRQDNDKGQLELVLKLGVLCSHEAEEVRPDMATVVKILNGVSE 611
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 49/208 (24%), Positives = 96/208 (46%), Gaps = 20/208 (10%)
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS---HTHLAFVHGVCVRGPE 682
P+ G G ++ +K + HD + E + +S + H +L + G C E
Sbjct 348 PVFKGTLSGSNAKIAVKRVS---HDSSQGMRELLAEISTIGRLRHPNLVRLLGYCRYKEE 404
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCG 737
+V +++ +G LD +L ++W + + + +ASALSYL + ++H ++
Sbjct 405 LYLVYDFLPNGSLDKYLYGTSDQKQLSWSQRFKIIKDVASALSYLHHGWIHVVIHRDIKP 464
Query 738 RNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAM 795
N+L+ ++ + G K+ D G + RV ++APE + G ++ T
Sbjct 465 ANVLIDDKMNASLGDFGLAKVYDQGYD----PQTSRVAGTFGYMAPEIMRTGRPTMGT-- 518
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEK 823
D + FG +LE+ D + + R+ SE+
Sbjct 519 DVYAFGMFMLEVSCDRKL-FEPRAESEE 545
>sp|Q5RFL3|M3K7_PONAB Mitogen-activated protein kinase kinase
kinase 7 OS=Pongo abelii OX=9601 GN=MAP3K7 PE=2 SV=1
Length=606
Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 79/284 (28%), Positives = 127/284 (45%), Gaps = 40/284 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + + VA+K ++++ R + E+ L + H +I+K
Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
G C + + LVMEY GSL + L P A + + Q +G+AYLH+
Sbjct 93 YGACLN----PVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148
Query 1019 ---YIHRDLAARNVLL-DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL N+LL ++KI DFG A + + + G + W APE +
Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTACDI----QTHMTNNKGSAA--WMAPEVFE 202
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ DV+S+G+ L+E++T + P F E+ G A R+ + G R
Sbjct 203 GSNYSEKCDVFSWGIILWEVITR----RKP---FDEIGGPA------FRIMWAVHNGTRP 249
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P P + LM CW + S RP+ E ++ I+ + + G
Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293
Score = 43.9 bits (102), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 57/233 (24%), Positives = 103/233 (44%), Gaps = 35/233 (15%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------ 707
AF +S+V+H ++ ++G C+ +V EY E G L L G P
Sbjct 73 AFIVELRQLSRVNHPNIVKLYGACLNPV--CLVMEYAEGGSLYNVLH---GAEPLPYYTA 127
Query 708 ---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
M+W + +Q +A L ++ K L+H ++ N+LL +A GT +K+ D G
Sbjct 128 AHAMSWCLQCSQGVA-YLHSMQPKALIHRDLKPPNLLL----VAGGT--VLKICDFGTAC 180
Query 765 GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ + W+APE G ++ S D + +G L E+ + + P+ +
Sbjct 181 DIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFR 238
Query 824 EHFYQRQ-------HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ LP+P + +L ++C + +P+QRPS I++ +T L
Sbjct 239 IMWAVHNGTRPPLIKNLPKP----IESLMTRCWSKDPSQRPSMEEIVKIMTHL 287
>sp|Q95ZQ4|AAPK2_CAEEL 5'-AMP-activated protein kinase catalytic
subunit alpha-2 OS=Caenorhabditis elegans OX=6239 GN=aak-2
PE=1 SV=2
Length=626
Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 71/198 (36%), Positives = 96/198 (48%), Gaps = 16/198 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSG-WKQEIDILRTLYHEHII 960
LG G FGKV + ++ T VAVK L + G ++EI L H HII
Sbjct 93 LGVGTFGKVKVGIHETTQ----YKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHPHII 148
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019
+ + + ++ME+V G L DY+ +H + A+ F QQI G+ Y H
Sbjct 149 RLYQVISTPSD--IFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMV 206
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDL N+LLD VKI DFGL+ + +G +R SP + APE + K Y
Sbjct 207 VHRDLKPENLLLDEQNNVKIADFGLSNIMTDGD---FLRTSCGSP-NYAAPEVISG-KLY 261
Query 1080 YA--SDVWSFGVTLYELL 1095
DVWS GV LY LL
Sbjct 262 AGPEVDVWSCGVILYALL 279
>sp|Q62073|M3K7_MOUSE Mitogen-activated protein kinase kinase
kinase 7 OS=Mus musculus OX=10090 GN=Map3k7 PE=1 SV=1
Length=579
Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 79/284 (28%), Positives = 127/284 (45%), Gaps = 40/284 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + + VA+K ++++ R + E+ L + H +I+K
Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
G C + + LVMEY GSL + L P A + + Q +G+AYLH+
Sbjct 93 YGACLN----PVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148
Query 1019 ---YIHRDLAARNVLL-DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL N+LL ++KI DFG A + + + G + W APE +
Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTACDI----QTHMTNNKGSAA--WMAPEVFE 202
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ DV+S+G+ L+E++T + P F E+ G A R+ + G R
Sbjct 203 GSNYSEKCDVFSWGIILWEVITR----RKP---FDEIGGPA------FRIMWAVHNGTRP 249
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P P + LM CW + S RP+ E ++ I+ + + G
Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293
Score = 43.9 bits (102), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 57/233 (24%), Positives = 103/233 (44%), Gaps = 35/233 (15%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------ 707
AF +S+V+H ++ ++G C+ +V EY E G L L G P
Sbjct 73 AFIVELRQLSRVNHPNIVKLYGACLNPV--CLVMEYAEGGSLYNVLH---GAEPLPYYTA 127
Query 708 ---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
M+W + +Q +A L ++ K L+H ++ N+LL +A GT +K+ D G
Sbjct 128 AHAMSWCLQCSQGVA-YLHSMQPKALIHRDLKPPNLLL----VAGGT--VLKICDFGTAC 180
Query 765 GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ + W+APE G ++ S D + +G L E+ + + P+ +
Sbjct 181 DIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFR 238
Query 824 EHFYQRQ-------HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ LP+P + +L ++C + +P+QRPS I++ +T L
Sbjct 239 IMWAVHNGTRPPLIKNLPKP----IESLMTRCWSKDPSQRPSMEEIVKIMTHL 287
>sp|O14098|CTK1_SCHPO CTD kinase subunit alpha OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=lsk1 PE=1
SV=1
Length=593
Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 73/233 (31%), Positives = 113/233 (48%), Gaps = 42/233 (18%)
Query 884 SPASDPT---VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH 940
SP S P + K +KI +GEG +GKV Y N TG++VA+K ++ + Q
Sbjct 261 SPPSGPIYTYTYPKPAYEKIDQIGEGTYGKV----YKAINTVTGDLVALKRIRLE---QE 313
Query 941 RSGWK----QEIDILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEY-------VPLGSLRD 988
+ G+ +E+ IL+ L H++I++ E EKS + +V EY V L S
Sbjct 314 KDGFPITTVREVKILQRLRHKNIVR---LLEIMVEKSSVYMVFEYMDHDLTGVLLNSQLH 370
Query 989 YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK-- 1046
+ P + ++QI E +AYLH + +HRD+ N+LL+N+ +K DFGLA+
Sbjct 371 FTP------GNIKHLSKQIFEALAYLHHRGVLHRDIKGSNILLNNNGDLKFADFGLARFN 424
Query 1047 -AVPEGHEYYRVREDGDSPVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096
+ + RV W+ P L E + A D+WS G + EL T
Sbjct 425 TSSKSANYTNRV------ITLWFRPPELLLGETAYDTAVDIWSAGCIVMELFT 471
Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 43/163 (26%), Positives = 76/163 (47%), Gaps = 15/163 (9%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
++ ++ H ++ + + V MV EY++H V L + P K + ++Q+
Sbjct 327 ILQRLRHKNIVRLLEIMVEKSSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHL-SKQIFE 385
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-----ERVER 775
AL+YL ++ ++H ++ G NILL G +K +D G+ S + RV
Sbjct 386 ALAYLHHRGVLHRDIKGSNILLNNNGD-------LKFADFGLARFNTSSKSANYTNRVIT 438
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ W P L G + TA+D W G ++E+ F G+ Q R
Sbjct 439 L-WFRPPELLLGETAYDTAVDIWSAGCIVMEL-FTGKPFFQGR 479
>sp|P46551|CDK12_CAEEL Cyclin-dependent kinase 12 OS=Caenorhabditis
elegans OX=6239 GN=cdk-12 PE=1 SV=4
Length=730
Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 65/210 (31%), Positives = 101/210 (48%), Gaps = 27/210 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958
+GEG +G+V Y N+ TGE VA+K ++ + + G+ +EI ILR L+H++
Sbjct 317 IGEGTYGQV----YKAVNNLTGEQVALKRVRLE---NEKEGFPITAIREIKILRQLHHKN 369
Query 959 IIKYKGCCED--------QGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQIC 1008
I++ D + + LV EYV L L + Q+ +Q+
Sbjct 370 IVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQLL 429
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
EG+AY+H ++HRD+ N+L++N +KI D GLA+ + Y R WY
Sbjct 430 EGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESRLYTNR----VITLWY 485
Query 1069 APE--CLKEYKFYYASDVWSFGVTLYELLT 1096
P L + ++ A DVWS G L EL T
Sbjct 486 RPPELLLGDERYGPAIDVWSTGCMLGELFT 515
Score = 36.6 bits (83), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 63/285 (22%), Positives = 115/285 (40%), Gaps = 49/285 (17%)
Query 541 GDDCFSLRRCCLPQPGETSNL-----IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHL 595
G S R+ LP P ++ + I R A+ R + S+++ + T L +
Sbjct 260 GGASSSKRQDPLPMPPDSKRIATRPVITTRRGHATNRPSDSD--SWYKTNLTHYTMLDQI 317
Query 596 GQGTRTNVYEGRLRVEGSGDP-EEGKMDDED---PLVPGRD----RGQELRVVLKVLDPS 647
G+GT VY+ + G + ++++E P+ R+ R + +++++D
Sbjct 318 GEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRLMDIV 377
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
DI+ M ++ T F +V EYV+H + + +E
Sbjct 378 IDDIS---------MDELKRTRANFY-----------LVFEYVDHDLIGLLESKELVDFN 417
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
+ +QL L+Y+ N +H ++ NIL+ G +K++D +GL L
Sbjct 418 KDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGE-------LKIAD--LGLARL 468
Query 768 -SREERV--ERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+E R+ R+ W P L G A+D W G L E+
Sbjct 469 WEKESRLYTNRVITLWYRPPELLLGDERYGPAIDVWSTGCMLGEL 513
>sp|P0C8E4|M3K7_RAT Mitogen-activated protein kinase kinase kinase
7 OS=Rattus norvegicus OX=10116 GN=Map3k7 PE=1 SV=1
Length=606
Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 79/284 (28%), Positives = 127/284 (45%), Gaps = 40/284 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + + VA+K ++++ R + E+ L + H +I+K
Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
G C + + LVMEY GSL + L P A + + Q +G+AYLH+
Sbjct 93 YGACLN----PVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148
Query 1019 ---YIHRDLAARNVLL-DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL N+LL ++KI DFG A + + + G + W APE +
Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTACDI----QTHMTNNKGSAA--WMAPEVFE 202
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ DV+S+G+ L+E++T + P F E+ G A R+ + G R
Sbjct 203 GSNYSEKCDVFSWGIILWEVITR----RKP---FDEIGGPA------FRIMWAVHNGTRP 249
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P P + LM CW + S RP+ E ++ I+ + + G
Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293
Score = 43.9 bits (102), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 57/233 (24%), Positives = 103/233 (44%), Gaps = 35/233 (15%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------ 707
AF +S+V+H ++ ++G C+ +V EY E G L L G P
Sbjct 73 AFIVELRQLSRVNHPNIVKLYGACLNPV--CLVMEYAEGGSLYNVLH---GAEPLPYYTA 127
Query 708 ---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
M+W + +Q +A L ++ K L+H ++ N+LL +A GT +K+ D G
Sbjct 128 AHAMSWCLQCSQGVA-YLHSMQPKALIHRDLKPPNLLL----VAGGT--VLKICDFGTAC 180
Query 765 GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ + W+APE G ++ S D + +G L E+ + + P+ +
Sbjct 181 DIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFR 238
Query 824 EHFYQRQ-------HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ LP+P + +L ++C + +P+QRPS I++ +T L
Sbjct 239 IMWAVHNGTRPPLIKNLPKP----IESLMTRCWSKDPSQRPSMEEIVKIMTHL 287
>sp|Q75DK7|STE20_EREGS Serine/threonine-protein kinase STE20 OS=Eremothecium
gossypii (strain ATCC 10895 / CBS 109.51 / FGSC
9923 / NRRL Y-1056) OX=284811 GN=STE20 PE=3 SV=2
Length=970
Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 54/208 (26%), Positives = 102/208 (49%), Gaps = 14/208 (7%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP+ ++ +K +G+G G V Y GT VA+K + + P+ + E
Sbjct 678 DPSKIYRNLVK----IGQGASGGV----YTAYEIGTNASVAIKQMNLEKQPK-KELIINE 728
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +++ H +I+ + +G+ L ++MEY+ GSL D + + Q+ +++
Sbjct 729 ILVMKGSRHNNIVNFIDSYLLKGD--LWVIMEYMEGGSLTDVVTHCILTEGQIAAVSRET 786
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
G+ +LH++ IHRD+ + N+LL D +K+ DFG + +E R +W
Sbjct 787 LRGLHFLHSKGVIHRDIKSDNILLSMDGNIKLTDFGFCAQI---NETNLKRTTMVGTPYW 843
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095
APE + ++ D+WS G+ + E++
Sbjct 844 MAPEVVSRKEYGPKVDIWSLGIMIIEMI 871
Score = 40.4 bits (93), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 45/192 (23%), Positives = 76/192 (40%), Gaps = 26/192 (14%)
Query 685 MVTEYVEHGPLDVWLRR---ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
++ EY+E G L + G + V+++ L +L +K ++H ++ NIL
Sbjct 755 VIMEYMEGGSLTDVVTHCILTEGQI-----AAVSRETLRGLHFLHSKGVIHRDIKSDNIL 809
Query 742 LARLGLAEGTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSLSTAMDK 797
L+ G IKL+D G + L R V W+APE + +D
Sbjct 810 LSMDG-------NIKLTDFGFCAQINETNLKRTTMVGTPYWMAPEVV--SRKEYGPKVDI 860
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH----RLPEPSCPQLATLTSQCLTYEP 853
W G ++E+ +GE P + +P + + + P L S CL P
Sbjct 861 WSLGIMIIEM-IEGEPPYLNETPLRALYLIATNGTPKLKDADSLSPVLKRFLSWCLQVSP 919
Query 854 TQRPSFRTILRD 865
R + +L D
Sbjct 920 NDRATAMELLYD 931
>sp|Q8K1R7|NEK9_MOUSE Serine/threonine-protein kinase Nek9 OS=Mus
musculus OX=10090 GN=Nek9 PE=1 SV=2
Length=984
Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 61/201 (30%), Positives = 100/201 (50%), Gaps = 13/201 (6%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEH 958
IR LG G FG+ +LY T D + +V K + + R EI IL L H++
Sbjct 55 IRVLGRGAFGEATLY--RRTEDDS--LVVWKEVDLTRLSEKERRDALNEIVILALLQHDN 110
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMAYLH 1015
II Y D +L + +EY G+L D + R L + ++ + QI ++ +H
Sbjct 111 IIAYYNHFMDN--TTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIH 168
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRD+ N+ L L+K+GD+GLAK + + Y + E ++ +PE +
Sbjct 169 KAGILHRDIKTLNIFLTKANLIKLGDYGLAKKL---NSEYSMAETLVGTPYYMSPELCQG 225
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
K+ + SD+W+ G ++ELLT
Sbjct 226 VKYNFKSDIWAVGCVIFELLT 246
>sp|O43318|M3K7_HUMAN Mitogen-activated protein kinase kinase
kinase 7 OS=Homo sapiens OX=9606 GN=MAP3K7 PE=1 SV=1
Length=606
Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 79/284 (28%), Positives = 127/284 (45%), Gaps = 40/284 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + + VA+K ++++ R + E+ L + H +I+K
Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
G C + + LVMEY GSL + L P A + + Q +G+AYLH+
Sbjct 93 YGACLN----PVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148
Query 1019 ---YIHRDLAARNVLL-DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL N+LL ++KI DFG A + + + G + W APE +
Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTACDI----QTHMTNNKGSAA--WMAPEVFE 202
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ DV+S+G+ L+E++T + P F E+ G A R+ + G R
Sbjct 203 GSNYSEKCDVFSWGIILWEVITR----RKP---FDEIGGPA------FRIMWAVHNGTRP 249
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P P + LM CW + S RP+ E ++ I+ + + G
Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293
Score = 43.9 bits (102), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 57/233 (24%), Positives = 103/233 (44%), Gaps = 35/233 (15%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------ 707
AF +S+V+H ++ ++G C+ +V EY E G L L G P
Sbjct 73 AFIVELRQLSRVNHPNIVKLYGACLNPV--CLVMEYAEGGSLYNVLH---GAEPLPYYTA 127
Query 708 ---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
M+W + +Q +A L ++ K L+H ++ N+LL +A GT +K+ D G
Sbjct 128 AHAMSWCLQCSQGVA-YLHSMQPKALIHRDLKPPNLLL----VAGGT--VLKICDFGTAC 180
Query 765 GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ + W+APE G ++ S D + +G L E+ + + P+ +
Sbjct 181 DIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFR 238
Query 824 EHFYQRQ-------HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ LP+P + +L ++C + +P+QRPS I++ +T L
Sbjct 239 IMWAVHNGTRPPLIKNLPKP----IESLMTRCWSKDPSQRPSMEEIVKIMTHL 287
>sp|P70218|M4K1_MOUSE Mitogen-activated protein kinase kinase
kinase kinase 1 OS=Mus musculus OX=10090 GN=Map4k1 PE=1 SV=1
Length=827
Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 61/214 (29%), Positives = 111/214 (52%), Gaps = 17/214 (8%)
Query 888 DPTVFHK---RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
DP +F+K + ++ LG G +G+V + + + ++VA+K +K + +
Sbjct 5 DPDIFNKDPREHYDLLQRLGGGTYGEV----FKARDKVSKDLVALKMVKMEPD-DDVATL 59
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLF 1003
++EI +L+T H +I+ Y G + L + ME+ GSL+D Y S+ Q+
Sbjct 60 QKEILMLKTCRHANIVAYHG--SYLWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYV 117
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+++ +G+AYLH++ IHRD+ N+L+++ VK+ DFG++ + G R +
Sbjct 118 CREVLQGLAYLHSEKKIHRDIKGANILINDCGEVKLADFGISAQI--GATLARRLSFIGT 175
Query 1064 PVFWYAPECLK---EYKFYYASDVWSFGVTLYEL 1094
P +W APE + + D+WS G+T EL
Sbjct 176 P-YWMAPEVAAVALKGGYNELCDIWSLGITAIEL 208
Score = 44.3 bits (103), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 47/187 (25%), Positives = 82/187 (44%), Gaps = 21/187 (11%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
RD+ + V LK++ D + ++ H ++ HG + + + E+
Sbjct 34 ARDKVSKDLVALKMVKMEPDDDVATLQKEILMLKTCRHANIVAYHGSYLWLQKLWICMEF 93
Query 690 VEHGPL-DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
G L D++ + G + V +++ L+YL ++ +H ++ G NIL+ G
Sbjct 94 CGAGSLQDIY--QVTGSLSELQISYVCREVLQGLAYLHSEKKIHRDIKGANILINDCG-- 149
Query 749 EGTSPFIKLSDPGVG--LGA-LSREERVERIP-WLAPE----CLPGGANSLSTAMDKWGF 800
+KL+D G+ +GA L+R P W+APE L GG N L D W
Sbjct 150 -----EVKLADFGISAQIGATLARRLSFIGTPYWMAPEVAAVALKGGYNELC---DIWSL 201
Query 801 GATLLEI 807
G T +E+
Sbjct 202 GITAIEL 208
>sp|P05986|KAPC_YEAST cAMP-dependent protein kinase type 3 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=TPK3 PE=1 SV=2
Length=398
Score = 84.0 bits (206), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 64/200 (32%), Positives = 99/200 (50%), Gaps = 17/200 (9%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTLYHE 957
+R LG G FG+V L ++ G A+K LK + + E +L + H
Sbjct 91 LRTLGTGSFGRVHLI----RSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHP 146
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL--LFAQQICEGMAYLH 1015
II+ G +D + + +VM+Y+ G L L R S + +A ++C + YLH
Sbjct 147 FIIRMWGTFQDS--QQVFMVMDYIEGGELFSLL-RKSQRFPNPVAKFYAAEVCLALEYLH 203
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
++ I+RDL N+LLD + +KI DFG AK VP+ Y + D + APE +
Sbjct 204 SKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVT--YTLCGTPD----YIAPEVVST 257
Query 1076 YKFYYASDVWSFGVTLYELL 1095
+ + D WSFGV +YE+L
Sbjct 258 KPYNKSVDWWSFGVLIYEML 277
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 45/197 (23%), Positives = 84/197 (43%), Gaps = 11/197 (6%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
++S VSH + + G + MV +Y+E G L LR+ + P A ++
Sbjct 139 MLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQ-RFPNPVAKFYAAEVCL 197
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-WL 779
AL YL +K++++ ++ NILL + G IK++D G + P ++
Sbjct 198 ALEYLHSKDIIYRDLKPENILLDKNG-------HIKITDFGFAKYVPDVTYTLCGTPDYI 250
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP 839
APE + + ++D W FG + E+ S + E+ + + P P
Sbjct 251 APEVV--STKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHP 308
Query 840 QLATLTSQCLTYEPTQR 856
L + +T + ++R
Sbjct 309 DAQDLLKKLITRDLSER 325
>sp|D4AE59|STK11_RAT Serine/threonine-protein kinase STK11 OS=Rattus
norvegicus OX=10116 GN=Stk11 PE=1 SV=2
Length=436
Score = 84.3 bits (207), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 96/198 (48%), Gaps = 6/198 (3%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG +GKV D + +K K P + K+EI +LR L H ++I+
Sbjct 55 LGEGSYGKVK-EVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHRNVIQL 113
Query 963 KGCCEDQGEKSLQLVMEYVPLG--SLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
++ ++ + +VMEY G + D +P + Q + +Q+ +G+ YLH+Q +
Sbjct 114 VDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFRQLIDGLEYLHSQGIV 173
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
H+D+ N+LL + +KI D G+A+A+ R SP F PE +
Sbjct 174 HKDIKPGNLLLTTNGTLKISDLGVAEALHPFAVDDTCRTSQGSPAFQ-PPEIANGLDTFS 232
Query 1080 -YASDVWSFGVTLYELLT 1096
+ D+WS GVTLY + T
Sbjct 233 GFKVDIWSAGVTLYNITT 250
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 56/210 (27%), Positives = 87/210 (41%), Gaps = 15/210 (7%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
MV EY G ++ P+ +QL L YL ++ +VH ++ N+LL
Sbjct 127 MVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFRQLIDGLEYLHSQGIVHKDIKPGNLLLT- 185
Query 745 LGLAEGTSPFIKLSDPGVGLG----ALSREERVER-IPWLAPECLPGGANSLST-AMDKW 798
T+ +K+SD GV A+ R + P P + G ++ S +D W
Sbjct 186 ------TNGTLKISDLGVAEALHPFAVDDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIW 239
Query 799 GFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857
G TL I G P + + + E+ + +P P L+ L L YEP +R
Sbjct 240 SAGVTLYNIT-TGLYPFEGDNIYKLFENIGRGDFTIPCDCAPPLSDLLRGMLEYEPAKRF 298
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
S R I + + H LA+ L P SP +
Sbjct 299 SIRQIRQHSWFRKKHPLAEALVPIPPSPDT 328
>sp|Q8C015|PAK5_MOUSE Serine/threonine-protein kinase PAK 5 OS=Mus
musculus OX=10090 GN=Pak5 PE=1 SV=1
Length=719
Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 63/223 (28%), Positives = 105/223 (47%), Gaps = 28/223 (13%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
L V+P P + YL +GEG G V + T TG+ VAVK K D
Sbjct 438 LVVSPGDP--------REYLDNFIKIGEGSTGIVCI----ATEKHTGKQVAVK--KMDLR 483
Query 938 PQHRSGWK-QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996
Q R E+ I+R +H++++ E L +VME++ G+L D + +
Sbjct 484 KQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDE--LWVVMEFLEGGALTDIVTHTRMN 541
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG----LAKAVPEGH 1052
Q+ + + ++YLH Q IHRD+ + ++LL +D +K+ DFG ++K VP+
Sbjct 542 EEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPK-- 599
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
R+ +W APE + + D+WS G+ + E++
Sbjct 600 -----RKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMI 637
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 52/191 (27%), Positives = 81/191 (42%), Gaps = 24/191 (13%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-D 696
+V +K +D + +M H ++ ++ + G E +V E++E G L D
Sbjct 474 QVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTD 533
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+ +A V + ALSYL N+ ++H ++ +ILL G IK
Sbjct 534 IVTHTRMNEEQIA---TVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGR-------IK 583
Query 757 LSDPG----VGLGALSREERVERIPWLAPEC---LPGGANSLSTAMDKWGFGATLLEICF 809
LSD G V R+ V W+APE LP G T +D W G ++E+
Sbjct 584 LSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYG-----TEVDIWSLGIMVIEM-I 637
Query 810 DGEAPLQSRSP 820
DGE P + P
Sbjct 638 DGEPPYFNEPP 648
>sp|D4A280|PAK5_RAT Serine/threonine-protein kinase PAK 5 OS=Rattus
norvegicus OX=10116 GN=Pak5 PE=1 SV=1
Length=718
Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 63/223 (28%), Positives = 105/223 (47%), Gaps = 28/223 (13%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
L V+P P + YL +GEG G V + T TG+ VAVK K D
Sbjct 437 LVVSPGDP--------REYLDNFIKIGEGSTGIVCI----ATEKHTGKQVAVK--KMDLR 482
Query 938 PQHRSGWK-QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996
Q R E+ I+R +H++++ E L +VME++ G+L D + +
Sbjct 483 KQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDE--LWVVMEFLEGGALTDIVTHTRMN 540
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG----LAKAVPEGH 1052
Q+ + + ++YLH Q IHRD+ + ++LL +D +K+ DFG ++K VP+
Sbjct 541 EEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPK-- 598
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
R+ +W APE + + D+WS G+ + E++
Sbjct 599 -----RKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMI 636
Score = 52.0 bits (123), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 52/191 (27%), Positives = 81/191 (42%), Gaps = 24/191 (13%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-D 696
+V +K +D + +M H ++ ++ + G E +V E++E G L D
Sbjct 473 QVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTD 532
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+ +A V + ALSYL N+ ++H ++ +ILL G IK
Sbjct 533 IVTHTRMNEEQIA---TVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGR-------IK 582
Query 757 LSDPG----VGLGALSREERVERIPWLAPEC---LPGGANSLSTAMDKWGFGATLLEICF 809
LSD G V R+ V W+APE LP G T +D W G ++E+
Sbjct 583 LSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYG-----TEVDIWSLGIMVIEM-I 636
Query 810 DGEAPLQSRSP 820
DGE P + P
Sbjct 637 DGEPPYFNEPP 647
>sp|Q9FIU5|CRLK1_ARATH Calcium/calmodulin-regulated receptor-like
kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CRLK1 PE=1 SV=1
Length=440
Score = 84.7 bits (208), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 65/220 (30%), Positives = 105/220 (48%), Gaps = 24/220 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FG V TGE+VAVK L D Q ++ E+ +L L+H +++
Sbjct 119 IGQGAFGPVY-----KAQMSTGEIVAVKVLATDS-KQGEKEFQTEVMLLGRLHHRNLVNL 172
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019
G C ++G+ L+ Y+ GSL +L +H + + A + G+ YLH
Sbjct 173 IGYCAEKGQH--MLIYVYMSKGSLASHLYSEKHEPLSWDLRVYIALDVARGLEYLHDGAV 230
Query 1020 ---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA-PECLKE 1075
IHRD+ + N+LLD ++ DFGL++ +R F Y PE +
Sbjct 231 PPVIHRDIKSSNILLDQSMRARVADFGLSREEMVDKHAANIR-----GTFGYLDPEYIST 285
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
F SDV+ FGV L+EL+ + ++P +EL+ +A
Sbjct 286 RTFTKKSDVYGFGVLLFELI----AGRNPQQGLMELVELA 321
Score = 60.5 bits (145), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 63/258 (24%), Positives = 112/258 (43%), Gaps = 43/258 (17%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +KVL F L+ ++ H +L + G C +++++ Y+ G L
Sbjct 138 VAVKVLATDSKQGEKEFQTEVMLLGRLHHRNLVNLIGYCAEKGQHMLIYVYMSKGSLASH 197
Query 699 LRRERGHVPMAW--KMVVAQQLASALSYLENKNL---VHGNVCGRNILLARLGLAEGTSP 753
L E+ H P++W ++ +A +A L YL + + +H ++ NILL + S
Sbjct 198 LYSEK-HEPLSWDLRVYIALDVARGLEYLHDGAVPPVIHRDIKSSNILLDQ-------SM 249
Query 754 FIKLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+++D G LSREE V++ +L PE + + + D +GFG L
Sbjct 250 RARVADFG-----LSREEMVDKHAANIRGTFGYLDPEYIS--TRTFTKKSDVYGFGVLLF 302
Query 806 EICFDGEAP---------LQSRSPSEK---EHFYQRQ--HRLPEPSCPQLATLTSQCLTY 851
E+ G P L + + EK E + R ++A +C++
Sbjct 303 EL-IAGRNPQQGLMELVELAAMNAEEKVGWEEIVDSRLDGRYDLQEVNEVAAFAYKCISR 361
Query 852 EPTQRPSFRTILRDLTRL 869
P +RP+ R I++ LTR+
Sbjct 362 APRKRPNMRDIVQVLTRV 379
>sp|Q9SGP2|HSL1_ARATH Receptor-like protein kinase HSL1 OS=Arabidopsis
thaliana OX=3702 GN=HSL1 PE=1 SV=1
Length=996
Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 69/217 (32%), Positives = 104/217 (48%), Gaps = 33/217 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-------KADCGPQ-------HRSGWKQEI 948
+G G GKV Y TN GE VAVK L DC P+ ++ E+
Sbjct 682 IGAGASGKV--YKVVLTN---GETVAVKRLWTGSVKETGDCDPEKGYKPGVQDEAFEAEV 736
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA------QLLL 1002
+ L + H++I+K CC + K LV EY+P GSL D L G+ +++L
Sbjct 737 ETLGKIRHKNIVKLWCCCSTRDCK--LLVYEYMPNGSLGDLLHSSKGGMLGWQTRFKIIL 794
Query 1003 FAQQICEGMAYLHAQHY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
A EG++YLH +HRD+ + N+L+D D ++ DFG+AKAV + +
Sbjct 795 DA---AEGLSYLHHDSVPPIVHRDIKSNNILIDGDYGARVADFGVAKAVDLTGKAPKSMS 851
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+ APE + SD++SFGV + E++T
Sbjct 852 VIAGSCGYIAPEYAYTLRVNEKSDIYSFGVVILEIVT 888
>sp|Q6P3R8|NEK5_HUMAN Serine/threonine-protein kinase Nek5 OS=Homo
sapiens OX=9606 GN=NEK5 PE=1 SV=1
Length=708
Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 57/202 (28%), Positives = 99/202 (49%), Gaps = 14/202 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEH 958
I+ +G+G FGK Y + +K + + P Q + K+E+ +L + H +
Sbjct 7 IKAIGQGAFGKA----YLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKHPN 62
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLH 1015
I+ + ++ G L +VMEY G L + R L Q+L + QI G+ ++H
Sbjct 63 IVAFFNSFQENGR--LFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIH 120
Query 1016 AQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+ +HRD+ A+N+ L + +V K+GDFG+A+ + E R ++ +PE +
Sbjct 121 DRKILHRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELART---CIGTPYYLSPEICQ 177
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ +D+WS G LYEL T
Sbjct 178 NKPYNNKTDIWSLGCVLYELCT 199
Score = 45.8 bits (107), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 51/220 (23%), Positives = 90/220 (41%), Gaps = 34/220 (15%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQL 718
L+ ++ H ++ +V EY + G L + R+RG V + ++ Q+
Sbjct 54 LLEKMKHPNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRG-VLFSEDQILGWFVQI 112
Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI-- 776
+ L ++ ++ ++H ++ +NI L++ G+ KL D G+ L+ + R
Sbjct 113 SLGLKHIHDRKILHRDIKAQNIFLSKNGMV------AKLGDFGIAR-VLNNSMELARTCI 165
Query 777 ---PWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQSRSPSEKEHFYQ 828
+L+PE + T D W G L E+C F+G Q + HF
Sbjct 166 GTPYYLSPEICQNKPYNNKT--DIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHF-- 221
Query 829 RQHRLPEPSCP----QLATLTSQCLTYEPTQRPSFRTILR 864
P P +L +L SQ P RPS +IL+
Sbjct 222 ------APISPGFSRELHSLISQLFQVSPRDRPSINSILK 255
>sp|C0LGQ5|GSO1_ARATH LRR receptor-like serine/threonine-protein
kinase GSO1 OS=Arabidopsis thaliana OX=3702 GN=GSO1 PE=1
SV=1
Length=1249
Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 79/282 (28%), Positives = 122/282 (43%), Gaps = 34/282 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G GKV Y + N GE VAVK + + +E+ L + H H++K
Sbjct 957 IGSGGSGKV--YKAELEN---GETVAVKKILWKDDLMSNKSFSREVKTLGRIRHRHLVKL 1011
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---------PRHSIGLAQLLLFAQQICEGMAY 1013
G C + E L+ EY+ GS+ D+L + + L A + +G+ Y
Sbjct 1012 MGYCSSKSEGLNLLIYEYMKNGSIWDWLHEDKPVLEKKKKLLDWEARLRIAVGLAQGVEY 1071
Query 1014 LH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-A 1069
LH +HRD+ + NVLLD++ +GDFGLAK + E + + + Y A
Sbjct 1072 LHHDCVPPIVHRDIKSSNVLLDSNMEAHLGDFGLAKVLTENCDTNTDSNTWFACSYGYIA 1131
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKF-------LELIGIAQGQM 1119
PE K SDV+S G+ L E++T DS LE+ G A+ ++
Sbjct 1132 PEYAYSLKATEKSDVYSMGIVLMEIVTGKMPTDSVFGAEMDMVRWVETHLEVAGSARDKL 1191
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+L L LP + C+V + C +T RP+
Sbjct 1192 IDPKLKPL------LPFEEDAACQVLEIALQCTKTSPQERPS 1227
Score = 35.0 bits (79), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 25/101 (25%), Positives = 48/101 (48%), Gaps = 12/101 (12%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEHGPLDVWLRR-----ERGHV 706
+F + ++ H HL + G C E N+++ EY+++G + WL E+
Sbjct 992 SFSREVKTLGRIRHRHLVKLMGYCSSKSEGLNLLIYEYMKNGSIWDWLHEDKPVLEKKKK 1051
Query 707 PMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILL 742
+ W ++ +A LA + YL + +VH ++ N+LL
Sbjct 1052 LLDWEARLRIAVGLAQGVEYLHHDCVPPIVHRDIKSSNVLL 1092
>sp|Q8VYT3|Y4052_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At4g30520 OS=Arabidopsis thaliana OX=3702
GN=At4g30520 PE=1 SV=1
Length=648
Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 66/198 (33%), Positives = 94/198 (47%), Gaps = 13/198 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V G G MVAVK LK G S ++ E++++ H+++++
Sbjct 309 LGAGGFGNVY-----RGKLGDGTMVAVKRLKDINGTSGDSQFRMELEMISLAVHKNLLRL 363
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ---H 1018
G C GE+ LV Y+P GS+ L + ++ A G+ YLH Q
Sbjct 364 IGYCATSGER--LLVYPYMPNGSVASKLKSKPALDWNMRKRIAIGAARGLLYLHEQCDPK 421
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ A N+LLD +GDFGLAK + + G V APE L +
Sbjct 422 IIHRDVKAANILLDECFEAVVGDFGLAKLLNHADSHVTTAVRG--TVGHIAPEYLSTGQS 479
Query 1079 YYASDVWSFGVTLYELLT 1096
+DV+ FG+ L EL+T
Sbjct 480 SEKTDVFGFGILLLELIT 497
>sp|C0LGT5|Y5169_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At5g16900 OS=Arabidopsis thaliana OX=3702
GN=At5g16900 PE=1 SV=1
Length=866
Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 63/204 (31%), Positives = 105/204 (51%), Gaps = 16/204 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R +GEG FG V + ND E VAVK L ++ +K E+++L ++H +++
Sbjct 577 RVIGEGGFGVV---YHGYLNDS--EQVAVKVLSPSSSQGYKE-FKAEVELLLRVHHINLV 630
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHS---IGLAQLLLFAQQICEGMAYLHA 1016
G C++Q L L+ EY+ G L+ +L +H + L A + G+ YLH+
Sbjct 631 SLVGYCDEQAH--LALIYEYMANGDLKSHLSGKHGDCVLKWENRLSIAVETALGLEYLHS 688
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+HRD+ + N+LLD K+ DFGL+++ G E + +P + PE
Sbjct 689 GCKPLMVHRDVKSMNILLDEHFQAKLADFGLSRSFSVGEESHVSTGVVGTPGYL-DPEYY 747
Query 1074 KEYKFYYASDVWSFGVTLYELLTH 1097
+ Y+ SDV+SFG+ L E++T+
Sbjct 748 RTYRLTEKSDVYSFGIVLLEIITN 771
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 63/240 (26%), Positives = 96/240 (40%), Gaps = 35/240 (15%)
Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660
TN +E + G G G ++D + +V +KVL PS F
Sbjct 572 TNNFERVIGEGGFGVVYHGYLNDSE------------QVAVKVLSPSSSQGYKEFKAEVE 619
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQL 718
L+ +V H +L + G C ++ EY+ +G L L + G + W ++ +A +
Sbjct 620 LLLRVHHINLVSLVGYCDEQAHLALIYEYMANGDLKSHLSGKHGDCVLKWENRLSIAVET 679
Query 719 ASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER--- 772
A L YL + +VH +V NILL A KL+D G+ EE
Sbjct 680 ALGLEYLHSGCKPLMVHRDVKSMNILLDEHFQA-------KLADFGLSRSFSVGEESHVS 732
Query 773 --VERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
V P +L PE L+ D + FG LLEI + Q+ +E H +R
Sbjct 733 TGVVGTPGYLDPEYY--RTYRLTEKSDVYSFGIVLLEIITNQPVLEQA---NENRHIAER 787
>sp|Q9ZVP5|M3K18_ARATH Mitogen-activated protein kinase kinase
kinase 18 OS=Arabidopsis thaliana OX=3702 GN=MAPKKK18 PE=1
SV=1
Length=339
Score = 83.2 bits (204), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 70/209 (33%), Positives = 106/209 (51%), Gaps = 29/209 (14%)
Query 901 RDLGEGHFGKVSL-YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ-EIDILRTLYHEH 958
+ LG G VS C++ +GE +AVK+ + HRS + Q E IL +L +
Sbjct 7 KTLGRGSTATVSAATCHE-----SGETLAVKSAEF-----HRSEFLQREAKILSSLNSPY 56
Query 959 IIKYKGC------CEDQGE-KSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICE 1009
+I Y+GC + GE + L+MEY P G+L D ++ I A+++ + +QI
Sbjct 57 VIGYRGCEITREPFHNNGEATTYSLLMEYAPYGTLTDVATKNGGFIDEARVVKYTRQILL 116
Query 1010 GMAYLHAQHYI-HRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFW 1067
G+ Y+H I H D+ NVL+ + KI DFG AK V PE E R +P F
Sbjct 117 GLEYIHNSKGIAHCDIKGSNVLVGENGEAKIADFGCAKWVEPEITEPVR-----GTPAF- 170
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096
APE + + SD+W+ G T+ E++T
Sbjct 171 MAPEAARGERQGKESDIWAVGCTVIEMVT 199
Score = 39.3 bits (90), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 47/214 (22%), Positives = 88/214 (41%), Gaps = 27/214 (13%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN-KNLVHGNVCGRNILLA 743
++ EY +G L + G + A + +Q+ L Y+ N K + H ++ G N+L+
Sbjct 81 LLMEYAPYGTLTDVATKNGGFIDEARVVKYTRQILLGLEYIHNSKGIAHCDIKGSNVLVG 140
Query 744 RLGLAE----GTSPFI--KLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDK 797
G A+ G + ++ ++++P G A +APE G + D
Sbjct 141 ENGEAKIADFGCAKWVEPEITEPVRGTPAF-----------MAPEAARGERQGKES--DI 187
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCP---QLATLTSQCLTYE 852
W G T++E+ + + + Y+ + LPE C Q +CL E
Sbjct 188 WAVGCTVIEMVTGSQPWIGADFTDPVSVLYRVGYLGELPELPCSLTEQAKDFLGKCLKKE 247
Query 853 PTQRPSFRTILRD--LTRLQPHNLADVLTVNPDS 884
T+R + +L L +P + ++T +P S
Sbjct 248 ATERWTASQLLNHPFLVNKEPELVTGLVTNSPTS 281
>sp|Q0GGW5|STK11_CHICK Serine/threonine-protein kinase STK11 OS=Gallus
gallus OX=9031 GN=STK11 PE=2 SV=1
Length=440
Score = 84.3 bits (207), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 60/198 (30%), Positives = 97/198 (49%), Gaps = 6/198 (3%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG +GKV D + +K K P + K+EI +LR L H+++I+
Sbjct 55 LGEGSYGKVK-EMLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQL 113
Query 963 KGCCEDQGEKSLQLVMEYVPLG--SLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
++ ++ + +VMEY G + D +P + Q + Q+ +G+ YLH+Q +
Sbjct 114 VDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVFQAHGYFCQLIDGLEYLHSQGIV 173
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
H+D+ N+LL + +KI D G+A+A+ E R SP F PE +
Sbjct 174 HKDIKPGNLLLTTNGTLKISDLGVAEALHPFAEDDTCRTSQGSPAFQ-PPEIANGLDTFS 232
Query 1080 -YASDVWSFGVTLYELLT 1096
+ D+WS GVTLY + T
Sbjct 233 GFKVDIWSAGVTLYNITT 250
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 47/181 (26%), Positives = 75/181 (41%), Gaps = 21/181 (12%)
Query 717 QLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPGVGLGALS 768
QL L YL ++ +VH ++ N+LL + LG+AE PF + G+
Sbjct 159 QLIDGLEYLHSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEALHPFAEDDTCRTSQGS-- 216
Query 769 REERVERIPWLAPECLPGGANSLST-AMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHF 826
P P + G ++ S +D W G TL I G P + + + E+
Sbjct 217 --------PAFQPPEIANGLDTFSGFKVDIWSAGVTLYNIT-TGLYPFEGDNIYKLFENI 267
Query 827 YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
+ +PE P L+ L L Y+P +R S + I + + H A+ L P SP
Sbjct 268 GKGDFTIPEDCGPPLSDLLRGMLEYDPAKRFSIQQIRQHNWFRKKHAQAETLVPIPPSPE 327
Query 887 S 887
+
Sbjct 328 T 328
>sp|P70032|PLK1_XENLA Serine/threonine-protein kinase PLK1 OS=Xenopus
laevis OX=8355 GN=plk1 PE=1 SV=1
Length=598
Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 63/197 (32%), Positives = 96/197 (49%), Gaps = 12/197 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960
LG+G F K CY+ T+ + E+ A K + P + EI I R+L H H++
Sbjct 50 LGKGGFAK----CYEITDLESREVFAGKIVPKTMLLKPHQKDKMTMEIAIQRSLDHRHVV 105
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G ED + +V+E SL + + R ++ + + +Q G YLH+
Sbjct 106 GFHGFFEDND--FVYVVLELCRRRSLLELHKRRKAVTEPEARYYLKQTISGCQYLHSNRV 163
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRDL N+ L+++ VKIGDFGLA V E R + +P + APE L +
Sbjct 164 IHRDLKLGNLFLNDEMEVKIGDFGLATKVEYDGE--RKKTLCGTPN-YIAPEVLGKKGHS 220
Query 1080 YASDVWSFGVTLYELLT 1096
+ D+WS G +Y LL
Sbjct 221 FEVDIWSIGCIMYTLLV 237
Score = 42.0 bits (97), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 47/211 (22%), Positives = 83/211 (39%), Gaps = 16/211 (8%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
++ + H H+ HG +V E L + L + R V +Q
Sbjct 94 AIQRSLDHRHVVGFHGFFEDNDFVYVVLELCRRRSL-LELHKRRKAVTEPEARYYLKQTI 152
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776
S YL + ++H R++ L L L + +K+ D G+ ER + +
Sbjct 153 SGCQYLHSNRVIH-----RDLKLGNLFLNDEME--VKIGDFGLATKVEYDGERKKTLCGT 205
Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLP 834
++APE L G S +D W G + + G+ P ++ E + ++ +P
Sbjct 206 PNYIAPEVL--GKKGHSFEVDIWSIGCIMYTLLV-GKPPFETSCLKETYMRIKKNEYSIP 262
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ P A L + L +PT RP+ +L D
Sbjct 263 KHINPVAAALIQKMLRSDPTSRPTIDDLLND 293
>sp|P93749|Y2197_ARATH Probable protein kinase At2g41970 OS=Arabidopsis
thaliana OX=3702 GN=At2g41970 PE=2 SV=1
Length=365
Score = 83.6 bits (205), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 73/283 (26%), Positives = 127/283 (45%), Gaps = 25/283 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG +G+V +C GE VA+K L A + S + ++ ++ L H+H ++
Sbjct 79 IGEGSYGRV--FC----GKFKGEAVAIKKLDASSSEEPDSDFTSQLSVVSRLKHDHFVEL 132
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQLLLFAQQICEGMA 1012
G C + + L+ ++ GSL D L P + Q + A +G+
Sbjct 133 LGYCLEANNRI--LIYQFATKGSLHDVLHGRKGVQGAEPGPVLNWNQRVKIAYGAAKGLE 190
Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWY 1068
+LH + +HRD+ + NVLL +D + K+ DF L A + + R G ++
Sbjct 191 FLHEKVQPPIVHRDVRSSNVLLFDDFVAKMADFNLTNASSDTAARLHSTRVLGT--FGYH 248
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + SDV+SFGV L ELLT + P L+ A +++ ++ +
Sbjct 249 APEYAMTGQITQKSDVYSFGVVLLELLTGRKPVDHTMPKGQQSLVTWATPRLSEDKVKQC 308
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
++ P K ++ + C + EA FRP ++ L+
Sbjct 309 IDPKLNNDFPPKAVAKLAAVAALCVQYEADFRPNMTIVVKALQ 351
Score = 39.3 bits (90), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 62/271 (23%), Positives = 111/271 (41%), Gaps = 38/271 (14%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
G+ +G+ V +K LD S + + F S++S++ H H + G C+ I++ +
Sbjct 90 GKFKGEA--VAIKKLDASSSEEPDSDFTSQLSVVSRLKHDHFVELLGYCLEANNRILIYQ 147
Query 689 YVEHGPL-DVWLRRE--RGHVP---MAW--KMVVAQQLASALSYLENK---NLVHGNVCG 737
+ G L DV R+ +G P + W ++ +A A L +L K +VH +V
Sbjct 148 FATKGSLHDVLHGRKGVQGAEPGPVLNWNQRVKIAYGAAKGLEFLHEKVQPPIVHRDVRS 207
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-ERIPWLAPECLPGGANSLSTAMD 796
N+LL +A+ L++ A RV + APE G ++ D
Sbjct 208 SNVLLFDDFVAKMAD--FNLTNASSDTAARLHSTRVLGTFGYHAPEYAMTG--QITQKSD 263
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFY------------------QRQHRLPEPSC 838
+ FG LLE+ G P+ P ++ + + P +
Sbjct 264 VYSFGVVLLEL-LTGRKPVDHTMPKGQQSLVTWATPRLSEDKVKQCIDPKLNNDFPPKAV 322
Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+LA + + C+ YE RP+ +++ L L
Sbjct 323 AKLAAVAALCVQYEADFRPNMTIVVKALQPL 353
>sp|Q9M020|LRK63_ARATH Lectin-domain containing receptor kinase
VI.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK63 PE=2 SV=1
Length=688
Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 67/213 (31%), Positives = 107/213 (50%), Gaps = 25/213 (12%)
Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---EIDILR 952
K+ R +G G FG V P++D +AVK + P G ++ EI+ L
Sbjct 361 FKENRIVGTGGFGTVFRGNLSSPSSD----QIAVKKIT----PNSMQGVREFIAEIESLG 412
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHS---IGLAQLLLFAQQ 1006
L H++++ +G C+ + + L L+ +Y+P GSL L PR S + A+
Sbjct 413 RLRHKNLVNLQGWCKQKND--LLLIYDYIPNGSLDSLLYSRPRQSGVVLSWNARFKIAKG 470
Query 1007 ICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
I G+ YLH + IHRD+ NVL+++D ++GDFGLA+ G + G
Sbjct 471 IASGLLYLHEEWEKVVIHRDIKPSNVLIEDDMNPRLGDFGLARLYERGSQSNTTVVVG-- 528
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+ + APE + K ASDV++FGV L E+++
Sbjct 529 TIGYMAPELARNGKSSSASDVFAFGVLLLEIVS 561
Score = 53.9 bits (128), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 62/262 (24%), Positives = 112/262 (43%), Gaps = 48/262 (18%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
++ +K + P+ F + ++ H +L + G C + + +++ +Y+ +G LD
Sbjct 387 QIAVKKITPNSMQGVREFIAEIESLGRLRHKNLVNLQGWCKQKNDLLLIYDYIPNGSLDS 446
Query 698 WL--RRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEG 750
L R + V ++W + +A+ +AS L YL K ++H ++ N+L + +
Sbjct 447 LLYSRPRQSGVVLSWNARFKIAKGIASGLLYLHEEWEKVVIHRDIKPSNVL-----IEDD 501
Query 751 TSPFIKLSDPGVG----LGALSREE-RVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+P +L D G+ G+ S V I ++APE G + S+A D + FG LL
Sbjct 502 MNP--RLGDFGLARLYERGSQSNTTVVVGTIGYMAPELARNGKS--SSASDVFAFGVLLL 557
Query 806 EICFDGEAPLQSRSPSEKEHFY--------QRQHRLPEPSCPQLA------------TLT 845
EI + R P++ F+ + + P+L +
Sbjct 558 EI-------VSGRRPTDSGTFFLADWVMELHARGEILHAVDPRLGFGYDGVEARLALVVG 610
Query 846 SQCLTYEPTQRPSFRTILRDLT 867
C PT RPS RT+LR L
Sbjct 611 LLCCHQRPTSRPSMRTVLRYLN 632
>sp|P18161|SPLB_DICDI Dual specificity protein kinase splB OS=Dictyostelium
discoideum OX=44689 GN=splB PE=2 SV=2
Length=1155
Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 81/283 (29%), Positives = 129/283 (46%), Gaps = 36/283 (13%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEH 958
I+ +GEG F +V + G VA+K LK Q + + +E+ L+ H++
Sbjct 856 IQKVGEGAFSEVWEGWWK------GIHVAIKKLKIIGDEEQFKERFIREVQNLKKGNHQN 909
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEGM 1011
I+ + G C K ++ EY+ GSL + L P+ +L A + G+
Sbjct 910 IVMFIGACY----KPACIITEYMAGGSLYNILHNPNSSTPKVKYSFPLVLKMATDMALGL 965
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAP 1070
+LH+ +HRDL ++N+LLD +KI DFGL++ EG + G W P
Sbjct 966 LHLHSITIVHRDLTSQNILLDELGNIKISDFGLSREKSREGS--MTMTNGGICNPRWRPP 1023
Query 1071 ECLKEYKFYYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E K Y DV+ F + ++E+LT + P F +L G +Q V
Sbjct 1024 ELTKNLGHYSEKVDVYCFSLVVWEILT----GEIP---FSDLDG-SQASAQVAY------ 1069
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
G R P P+ C E+ L+ CWE + + RP F ++ LK +
Sbjct 1070 AGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKLKEI 1112
Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 62/229 (27%), Positives = 92/229 (40%), Gaps = 39/229 (17%)
Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP-------MAWKMVVAQQL 718
+H ++ G C + ++TEY+ G L L P + KM A +
Sbjct 906 NHQNIVMFIGACYKPA--CIITEYMAGGSLYNILHNPNSSTPKVKYSFPLVLKM--ATDM 961
Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE---- 774
A L +L + +VH ++ +NILL LG IK+SD G LSRE+ E
Sbjct 962 ALGLLHLHSITIVHRDLTSQNILLDELG-------NIKISDFG-----LSREKSREGSMT 1009
Query 775 -------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP---LQSRSPSEKE 824
W PE L S +D + F + EI GE P L S +
Sbjct 1010 MTNGGICNPRWRPPE-LTKNLGHYSEKVDVYCFSLVVWEI-LTGEIPFSDLDGSQASAQV 1067
Query 825 HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
+ + +PE P+L L +QC +P RP F I+ L + +N
Sbjct 1068 AYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKLKEISWNN 1116
>sp|Q8LKZ1|NORK_PEA Nodulation receptor kinase OS=Pisum sativum
OX=3888 GN=NORK PE=1 SV=1
Length=924
Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 78/278 (28%), Positives = 130/278 (47%), Gaps = 28/278 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG V Y T D G+ VAVK +++ Q + E+++L + HE+++
Sbjct 601 IGEGGFGSV----YRGTLDD-GQEVAVK-VRSATSTQGTREFDNELNLLSAIQHENLVPL 654
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHA- 1016
G C + ++ L V ++ GSL D L R + L A G+AYLH
Sbjct 655 LGYCNEYDQQIL--VYPFMSNGSLLDRLYGEPAKRKILDWPTRLSIALGAARGLAYLHTF 712
Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECL 1073
+ IHRD+ + N+LLD+ K+ DFG +K P EG Y + G + + PE
Sbjct 713 PGRSVIHRDVKSSNILLDHSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAG--YLDPEYY 770
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSP-----PTKFLELIGIAQGQMTVLRLTELL 1128
K + SDV+SFGV L E++ S + P P L+ A+ + ++ E++
Sbjct 771 KTQQLSEKSDVFSFGVVLLEIV----SGREPLNIKRPRVEWSLVEWAKPYIRASKVDEIV 826
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ G + + V + C E +++RP +++
Sbjct 827 DPGIKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIV 864
Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 68/259 (26%), Positives = 102/259 (39%), Gaps = 30/259 (12%)
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
D GQE V +KV + F +L+S + H +L + G C + I+V ++
Sbjct 615 DDGQE--VAVKVRSATSTQGTREFDNELNLLSAIQHENLVPLLGYCNEYDQQILVYPFMS 672
Query 692 HGPLDVWLRRE---RGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARL 745
+G L L E R + ++ +A A L+YL ++++H +V NILL
Sbjct 673 NGSLLDRLYGEPAKRKILDWPTRLSIALGAARGLAYLHTFPGRSVIHRDVKSSNILLDHS 732
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
A+ P G +S E R +L PE LS D + FG LL
Sbjct 733 MCAKVADFGFSKYAPQEGDSYVSLEVR-GTAGYLDPEYYK--TQQLSEKSDVFSFGVVLL 789
Query 806 EICFDGEAPLQSRSPS------EKEHFYQRQHRLPEPSCP------------QLATLTSQ 847
EI G PL + P E Y R ++ E P ++ + Q
Sbjct 790 EIV-SGREPLNIKRPRVEWSLVEWAKPYIRASKVDEIVDPGIKGGYHAEALWRVVEVALQ 848
Query 848 CLTYEPTQRPSFRTILRDL 866
CL T RP I+R+L
Sbjct 849 CLEPYSTYRPCMVDIVREL 867
>sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo
sapiens OX=9606 GN=RPS6KA1 PE=1 SV=2
Length=735
Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 64/219 (29%), Positives = 113/219 (52%), Gaps = 13/219 (6%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGP 938
V S +DP+ F + ++ LG+G FGKV L T +G + A+K LK A
Sbjct 50 VKAGSEKADPSHF-----ELLKVLGQGSFGKVFL-VRKVTRPDSGHLYAMKVLKKATLKV 103
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA 998
+ R K E DIL + H ++K + +G+ L L+++++ G L L + +
Sbjct 104 RDRVRTKMERDILADVNHPFVVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTE 161
Query 999 Q-LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ + + ++ G+ +LH+ I+RDL N+LLD + +K+ DFGL+K E ++ +
Sbjct 162 EDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKK 218
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
V + APE + +++D WS+GV ++E+LT
Sbjct 219 AYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLT 257
Score = 60.1 bits (144), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 58/189 (31%), Positives = 86/189 (46%), Gaps = 23/189 (12%)
Query 946 QEIDIL-RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA 1004
+EI+IL R H +II K +D K + LV E + G L D + R + F
Sbjct 458 EEIEILLRYGQHPNIITLKDVYDDG--KHVYLVTELMRGGELLDKILRQKFFSEREASFV 515
Query 1005 -QQICEGMAYLHAQHYIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
I + + YLH+Q +HRDL N+L N ++I DFG AK + E
Sbjct 516 LHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRA--------E 567
Query 1060 DG--DSPVF---WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LI 1112
+G +P + + APE LK + D+WS G+ LY +L + P+ E L
Sbjct 568 NGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILT 627
Query 1113 GIAQGQMTV 1121
I G+ T+
Sbjct 628 RIGSGKFTL 636
>sp|Q9SY89|Y1661_ARATH Putative G-type lectin S-receptor-like
serine/threonine-protein kinase At1g61610 OS=Arabidopsis thaliana
OX=3702 GN=At1g61610 PE=3 SV=1
Length=842
Score = 85.9 bits (211), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 79/282 (28%), Positives = 125/282 (44%), Gaps = 28/282 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V N G +AVK L Q +K EI ++ L H ++++
Sbjct 531 LGQGGFGTVY-----KGNFSEGREIAVKRLSGK-SKQGLEEFKNEILLIAKLQHRNLVRL 584
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017
GCC + EK L+ EY+P SL +L + S+ + I G+ YLH
Sbjct 585 LGCCIEDNEK--MLLYEYMPNKSLDRFLFDESKQGSLDWRKRWEVIGGIARGLLYLHRDS 642
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV------FWYA 1069
IHRDL A N+LLD + KI DFG+A+ + R+D + + + A
Sbjct 643 RLKIIHRDLKASNILLDTEMNPKISDFGMARI-------FNYRQDHANTIRVVGTYGYMA 695
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE E F SDV+SFGV + E+++ + T LIG A + + E+++
Sbjct 696 PEYAMEGIFSEKSDVYSFGVLILEIVSGRKNVSFRGTDHGSLIGYAWHLWSQGKTKEMID 755
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ R H+ C + RP +++ +L++
Sbjct 756 PIVKDTRDVTEAMRCIHVGMLCTQDSVIHRPNMGSVLLMLES 797
Score = 42.0 bits (97), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 42/164 (26%), Positives = 71/164 (43%), Gaps = 20/164 (12%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F L++++ H +L + G C+ E +++ EY+ + LD +L E + W +
Sbjct 566 FKNEILLIAKLQHRNLVRLLGCCIEDNEKMLLYEYMPNKSLDRFLFDESKQGSLDWRKRW 625
Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
V +A L YL + ++H ++ NILL T K+SD G+ R
Sbjct 626 EVIGGIARGLLYLHRDSRLKIIHRDLKASNILL-------DTEMNPKISDFGMARIFNYR 678
Query 770 EERVERI------PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
++ I ++APE G S D + FG +LEI
Sbjct 679 QDHANTIRVVGTYGYMAPEYAMEGI--FSEKSDVYSFGVLILEI 720
>sp|Q9M1Z9|LRK58_ARATH Putative L-type lectin-domain containing
receptor kinase V.8 OS=Arabidopsis thaliana OX=3702 GN=LECRK58
PE=3 SV=1
Length=626
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 65/207 (31%), Positives = 106/207 (51%), Gaps = 18/207 (9%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
K+ + LG+G FG+V + T G+ +AVK D Q S + EI + L H
Sbjct 303 FKEKQLLGKGGFGQV----FKGTLPGSNAEIAVKRTSHDS-RQGMSEFLAEISTIGRLRH 357
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMA 1012
++++ G C + ++L LV ++ P GSL YL R+ + Q + + +
Sbjct 358 PNLVRLLGYCRHK--ENLYLVYDFTPNGSLDKYLDRNENQERLTWEQRFKIIKDVASALL 415
Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068
+LH Q IHRD+ NVL+D++ +IGDFGLAK +G + R G F Y
Sbjct 416 HLHQEWVQIIIHRDIKPANVLIDHEMNARIGDFGLAKLYDQGLDPQTSRVAG---TFGYI 472
Query 1069 APECLKEYKFYYASDVWSFGVTLYELL 1095
APE L+ + ++DV++FG+ + E++
Sbjct 473 APELLRTGRATTSTDVYAFGLVMLEVV 499
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 47/178 (26%), Positives = 84/178 (47%), Gaps = 16/178 (9%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAW--K 711
F S + ++ H +L + G C R EN+ +V ++ +G LD +L R + W +
Sbjct 345 FLAEISTIGRLRHPNLVRLLGYC-RHKENLYLVYDFTPNGSLDKYLDRNENQERLTWEQR 403
Query 712 MVVAQQLASALSYLEN---KNLVHGNVCGRNILLA-RLGLAEGTSPFIKLSDPGVGLGAL 767
+ + +ASAL +L + ++H ++ N+L+ + G KL D G+
Sbjct 404 FKIIKDVASALLHLHQEWVQIIIHRDIKPANVLIDHEMNARIGDFGLAKLYDQGLD---- 459
Query 768 SREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ RV ++APE L G + ST D + FG +LE+ G ++ R+P +E
Sbjct 460 PQTSRVAGTFGYIAPELLRTGRATTST--DVYAFGLVMLEVVC-GRRMIERRAPENEE 514
>sp|O75011|NAK1_SCHPO Serine/threonine-protein kinase nak1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=nak1 PE=1 SV=1
Length=652
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 61/202 (30%), Positives = 99/202 (49%), Gaps = 13/202 (6%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH-- 956
K+ +G G +G V Y + T E VA+K L D S ++E+ +L L
Sbjct 12 KLELVGRGSYGAV----YRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQSD 67
Query 957 -EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH 1015
E+IIKY G +L ++M+Y GS+R + I + L ++ + + ++H
Sbjct 68 VENIIKYHGSY--LVGTNLWIIMDYCHGGSVRTLMEAGPISEPCISLILRETLQALKFIH 125
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
IHRD+ A N+L+ VK+ DFG+A E + R R +W APE +++
Sbjct 126 HAGIIHRDIKAANILVSMSGNVKLCDFGVAA---ELNINRRKRITFIGTPYWMAPEVIRD 182
Query 1076 YKFYYA-SDVWSFGVTLYELLT 1096
+ Y +D+WS G+T YE+ T
Sbjct 183 GQEYNVMADIWSLGITAYEIAT 204
Score = 41.2 bits (95), Expect = 0.067, Method: Compositional matrix adjust.
Identities = 41/178 (23%), Positives = 77/178 (43%), Gaps = 18/178 (10%)
Query 639 VVLKVL--DPSHHDIALAFYETASL--MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
V +K+L D +++ E A L + Q ++ HG + G ++ +Y G
Sbjct 36 VAIKILNLDTDEDEVSDIQKEVAVLSELKQSDVENIIKYHGSYLVGTNLWIIMDYCHGGS 95
Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+ + E G + ++ ++ AL ++ + ++H ++ NIL++ G
Sbjct 96 VRTLM--EAGPISEPCISLILRETLQALKFIHHAGIIHRDIKAANILVSMSG-------N 146
Query 755 IKLSDPGVGLG-ALSREERVERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+KL D GV ++R +R+ I W+APE + G + D W G T EI
Sbjct 147 VKLCDFGVAAELNINRRKRITFIGTPYWMAPEVIRDG-QEYNVMADIWSLGITAYEIA 203
>sp|O81832|Y4729_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At4g27290 OS=Arabidopsis thaliana OX=3702
GN=At4g27290 PE=3 SV=4
Length=783
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 70/204 (34%), Positives = 100/204 (49%), Gaps = 22/204 (11%)
Query 903 LGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG V +L C G+ VAVK L + Q +K EI ++ L H ++
Sbjct 471 LGQGGFGPVYKGTLAC--------GQEVAVKRL-SRTSRQGVEEFKNEIKLIAKLQHRNL 521
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015
+K G C D+ E+ L+ EY P SL ++ R + + + + I GM YLH
Sbjct 522 VKILGYCVDEEER--MLIYEYQPNKSLDSFIFDKERRRELDWPKRVEIIKGIARGMLYLH 579
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
IHRDL A NVLLD+D KI DFGLA+ + G E + +PE
Sbjct 580 EDSRLRIIHRDLKASNVLLDSDMNAKISDFGLARTLG-GDETEANTTRVVGTYGYMSPEY 638
Query 1073 LKEYKFYYASDVWSFGVTLYELLT 1096
+ F SDV+SFGV + E+++
Sbjct 639 QIDGYFSLKSDVFSFGVLVLEIVS 662
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 45/185 (24%), Positives = 83/185 (45%), Gaps = 22/185 (12%)
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
GQE V +K L + F L++++ H +L + G CV E +++ EY +
Sbjct 487 GQE--VAVKRLSRTSRQGVEEFKNEIKLIAKLQHRNLVKILGYCVDEEERMLIYEYQPNK 544
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLA 748
LD ++ + + W ++ + + +A + YL + ++H ++ N+LL
Sbjct 545 SLDSFIFDKERRRELDWPKRVEIIKGIARGMLYLHEDSRLRIIHRDLKASNVLL------ 598
Query 749 EGTSPFIKLSDPGVG--LGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGA 802
+ K+SD G+ LG E R+ +++PE G SL + D + FG
Sbjct 599 -DSDMNAKISDFGLARTLGGDETEANTTRVVGTYGYMSPEYQIDGYFSLKS--DVFSFGV 655
Query 803 TLLEI 807
+LEI
Sbjct 656 LVLEI 660
>sp|Q5Z6X0|CIPKP_ORYSJ CBL-interacting protein kinase 25 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK25 PE=2 SV=1
Length=514
Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 67/205 (33%), Positives = 103/205 (50%), Gaps = 20/205 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG----WKQEIDILRTLYHEH 958
+GEG+F KV Y + TGE VA+K + D R G K+EI +++ L H +
Sbjct 27 VGEGNFAKV----YLGRHRATGEEVAIKVM--DKEKLVRLGATELIKREIAVMQRLRHPN 80
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL------FAQQICEGMA 1012
+++ ++ + + +VMEYV G+L Y R G A L F QQ+ +A
Sbjct 81 VVRIHEVMANK--RRICVVMEYVRGGALYRYFRRGPSGGAAGLREHEARRFFQQLVSAVA 138
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Y H++ HRD+ N+L+D +K+ DFGL+ ++ +P+F APE
Sbjct 139 YCHSRGVFHRDIKLDNLLVDEQGNLKVADFGLSALADMERREAHLQTVCGTPLFL-APEV 197
Query 1073 LKEYKFYYA-SDVWSFGVTLYELLT 1096
K + A +DVW+ GV LY LLT
Sbjct 198 FKRRGYDGAKADVWACGVVLYVLLT 222
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 67/257 (26%), Positives = 102/257 (40%), Gaps = 41/257 (16%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYE----TASLMSQVSHTHLAFVHGVCVRGPENIM 685
GR R V +KV+D + L E ++M ++ H ++ +H V +
Sbjct 38 GRHRATGEEVAIKVMDKEKL-VRLGATELIKREIAVMQRLRHPNVVRIHEVMANKRRICV 96
Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVA----QQLASALSYLENKNLVHGNVCGRNIL 741
V EYV G L + RR + A QQL SA++Y ++ + H ++ N+L
Sbjct 97 VMEYVRGGALYRYFRRGPSGGAAGLREHEARRFFQQLVSAVAYCHSRGVFHRDIKLDNLL 156
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVER-------IP-WLAPECLPGGANSLST 793
+ G +K++D GL AL+ ER E P +LAPE +
Sbjct 157 VDEQG-------NLKVAD--FGLSALADMERREAHLQTVCGTPLFLAPEVFKRRGYDGAK 207
Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-------QRQHRLPEPSCPQLATLTS 846
A D W G L + L R P EH Q Q + P P LA L
Sbjct 208 A-DVWACGVVLYVL-------LTGRKPFPDEHVSRLYRLIGQNQFQCPPSFSPDLARLVR 259
Query 847 QCLTYEPTQRPSFRTIL 863
+ L +P +R + I+
Sbjct 260 RLLQPDPDRRITIPEIM 276
>sp|Q6CVA2|STE20_KLULA Serine/threonine-protein kinase STE20 OS=Kluyveromyces
lactis (strain ATCC 8585 / CBS 2359 / DSM 70799
/ NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=STE20 PE=3
SV=1
Length=989
Score = 85.9 bits (211), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 55/208 (26%), Positives = 103/208 (50%), Gaps = 14/208 (7%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP+ +K +K +G+G G V Y GT VA+K + + P+ + E
Sbjct 693 DPSKLYKNLIK----IGQGASGGV----YTAYELGTNASVAIKQMNLEKQPK-KELIVNE 743
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +++ H +I+ + +G+ L +VMEY+ GSL D + + Q+ +++
Sbjct 744 ILVMKGSKHNNIVNFIDSYLFRGD--LWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRET 801
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+G+ +LH++ IHRD+ + N+LL + +K+ DFG + +E R +W
Sbjct 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQI---NEVNLKRTTMVGTPYW 858
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095
APE + ++ D+WS G+ + E++
Sbjct 859 MAPEVVSRKEYGPKVDIWSLGIMIIEMI 886
Score = 42.4 bits (98), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 55/229 (24%), Positives = 97/229 (42%), Gaps = 30/229 (13%)
Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMV--VAQ 716
+M H ++ F+ RG + +V EY+E G L DV H + + V++
Sbjct 746 VMKGSKHNNIVNFIDSYLFRG-DLWVVMEYMEGGSLTDVVT-----HCILTEGQIGAVSR 799
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREER 772
+ L +L +K ++H ++ NILL+ G IKL+D G + L R
Sbjct 800 ETLKGLQFLHSKGVIHRDIKSDNILLSMNG-------DIKLTDFGFCAQINEVNLKRTTM 852
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH- 831
V W+APE + +D W G ++E+ +GE P + +P +
Sbjct 853 VGTPYWMAPEVV--SRKEYGPKVDIWSLGIMIIEM-IEGEPPYLNETPLRALYLIATNGT 909
Query 832 -RLPEPS--CPQLATLTSQCLTYEPTQRPSFRTILRD--LTRLQPHNLA 875
+L +P ++A + CL +P R + +L D +T + N +
Sbjct 910 PKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTS 958
>sp|Q3ULB5|PAK6_MOUSE Serine/threonine-protein kinase PAK 6 OS=Mus
musculus OX=10090 GN=Pak6 PE=2 SV=1
Length=682
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 63/213 (30%), Positives = 105/213 (49%), Gaps = 24/213 (11%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP + Y+K +GEG G V L +G VAVK + Q R E
Sbjct 403 DPRLLLDSYVK----IGEGSTGIVCLA----REKHSGRQVAVKMMDLRKQ-QRRELLFNE 453
Query 948 IDILRTLYHEHIIK-YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006
+ I+R H ++++ YK GE+ L ++ME++ G+L D + + + Q+ +
Sbjct 454 VVIMRDYQHLNVVEMYKSYLV--GEE-LWVLMEFLQGGALTDIISQVRLNEEQIATVCEA 510
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG----LAKAVPEGHEYYRVREDGD 1062
+ + +AYLHAQ IHRD+ + ++LL D VK+ DFG ++K VP+ R+
Sbjct 511 VLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPK-------RKSLV 563
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+W APE + + D+WS G+ + E++
Sbjct 564 GTPYWMAPEVISRSLYATEVDIWSLGIMVIEMV 596
Score = 47.4 bits (111), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 57/249 (23%), Positives = 106/249 (43%), Gaps = 34/249 (14%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
R++ +V +K++D + +M H ++ ++ + G E ++ E+
Sbjct 425 AREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHLNVVEMYKSYLVGEELWVLMEF 484
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
++ G L + + R + V + + AL+YL + ++H ++ +ILL G
Sbjct 485 LQGGALTDIISQVR--LNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDG--- 539
Query 750 GTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSL-STAMDKWGFGATL 804
+KLSD G + R+ V W+APE + + SL +T +D W G +
Sbjct 540 ----RVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVI---SRSLYATEVDIWSLGIMV 592
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT----------LTSQCLTYEPT 854
+E+ DGE P S SP Q RL + + P+L + L EP
Sbjct 593 IEMV-DGEPPYFSDSP------VQAMKRLRDSAPPKLKNSYKVSPVLRDFLDRMLVREPQ 645
Query 855 QRPSFRTIL 863
+R + + +L
Sbjct 646 ERATAQELL 654
>sp|P62205|PLK1_XENTR Serine/threonine-protein kinase PLK1 OS=Xenopus
tropicalis OX=8364 GN=plk1 PE=2 SV=1
Length=598
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 73/267 (27%), Positives = 119/267 (45%), Gaps = 28/267 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960
LG+G F K CY+ T+ + E+ A K + P + EI I R+L H H++
Sbjct 50 LGKGGFAK----CYEITDLESREVFAGKIVPKTMLLKPHQKDKMTMEIAIQRSLDHRHVV 105
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G ED + +V+E SL + + R ++ + + +Q G YLH+
Sbjct 106 GFHGFFEDND--FVYVVLELCRRRSLLELHKRRKAVTEPEARYYLKQTILGCQYLHSNRV 163
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRDL N+ L+++ VKIGDFGLA V E R + +P + APE L +
Sbjct 164 IHRDLKLGNLFLNDEMEVKIGDFGLATKVEYDGE--RKKTLCGTPN-YIAPEVLGKKGHS 220
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+ D+WS G +Y L L+G + + L+ T + + P
Sbjct 221 FEVDIWSIGCIMYTL----------------LVGKPPFETSCLKETYMRIKKNEYSVPKH 264
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLI 1166
L++ +E + RPT ++L+
Sbjct 265 INPMATALIQKMLRSEPTSRPTIDDLL 291
Score = 39.7 bits (91), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 46/211 (22%), Positives = 81/211 (38%), Gaps = 16/211 (8%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
++ + H H+ HG +V E L + L + R V +Q
Sbjct 94 AIQRSLDHRHVVGFHGFFEDNDFVYVVLELCRRRSL-LELHKRRKAVTEPEARYYLKQTI 152
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776
YL + ++H R++ L L L + +K+ D G+ ER + +
Sbjct 153 LGCQYLHSNRVIH-----RDLKLGNLFLNDEME--VKIGDFGLATKVEYDGERKKTLCGT 205
Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLP 834
++APE L G S +D W G + + G+ P ++ E + ++ +P
Sbjct 206 PNYIAPEVL--GKKGHSFEVDIWSIGCIMYTLLV-GKPPFETSCLKETYMRIKKNEYSVP 262
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ P L + L EPT RP+ +L D
Sbjct 263 KHINPMATALIQKMLRSEPTSRPTIDDLLND 293
>sp|Q9P286|PAK5_HUMAN Serine/threonine-protein kinase PAK 5 OS=Homo
sapiens OX=9606 GN=PAK5 PE=1 SV=1
Length=719
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 63/223 (28%), Positives = 104/223 (47%), Gaps = 28/223 (13%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
L V+P P + YL +GEG G V + T TG+ VAVK K D
Sbjct 438 LVVSPGDP--------REYLANFIKIGEGSTGIVCI----ATEKHTGKQVAVK--KMDLR 483
Query 938 PQHRSGWK-QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996
Q R E+ I+R +H++++ E L +VME++ G+L D + +
Sbjct 484 KQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDE--LWVVMEFLEGGALTDIVTHTRMN 541
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG----LAKAVPEGH 1052
Q+ + ++YLH Q IHRD+ + ++LL +D +K+ DFG ++K VP+
Sbjct 542 EEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPK-- 599
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
R+ +W APE + + D+WS G+ + E++
Sbjct 600 -----RKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMI 637
Score = 51.2 bits (121), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 52/191 (27%), Positives = 81/191 (42%), Gaps = 24/191 (13%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-D 696
+V +K +D + +M H ++ ++ + G E +V E++E G L D
Sbjct 474 QVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTD 533
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+ +A V + ALSYL N+ ++H ++ +ILL G IK
Sbjct 534 IVTHTRMNEEQIA---TVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGR-------IK 583
Query 757 LSDPG----VGLGALSREERVERIPWLAPEC---LPGGANSLSTAMDKWGFGATLLEICF 809
LSD G V R+ V W+APE LP G T +D W G ++E+
Sbjct 584 LSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYG-----TEVDIWSLGIMVIEM-I 637
Query 810 DGEAPLQSRSP 820
DGE P + P
Sbjct 638 DGEPPYFNEPP 648
>sp|C0LGG6|Y5189_ARATH Probable LRR receptor-like protein kinase
At1g51890 OS=Arabidopsis thaliana OX=3702 GN=At1g51890 PE=1
SV=2
Length=876
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 62/204 (30%), Positives = 103/204 (50%), Gaps = 17/204 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LG+G FG V D T VAVK L ++ +K E+++L ++H H++
Sbjct 574 RVLGKGGFGTVYHGNLDDT------QVAVKMLSHSSAQGYKE-FKAEVELLLRVHHRHLV 626
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQL---LLFAQQICEGMAYLHA 1016
G C+D +L L+ EY+ G LR+ + +HS+ + + A + +G+ YLH
Sbjct 627 GLVGYCDDG--DNLALIYEYMEKGDLRENMSGKHSVNVLSWETRMQIAVEAAQGLEYLHN 684
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+HRD+ N+LL+ K+ DFGL+++ P E + + +P + PE
Sbjct 685 GCRPPMVHRDVKPTNILLNERSQAKLADFGLSRSFPVDGESHVMTVVAGTPGY-LDPEYY 743
Query 1074 KEYKFYYASDVWSFGVTLYELLTH 1097
+ SDV+SFGV L E++T+
Sbjct 744 RTNWLSEKSDVYSFGVVLLEIVTN 767
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 61/219 (28%), Positives = 87/219 (40%), Gaps = 33/219 (15%)
Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660
T +E L G G G +DD +V +K+L S F
Sbjct 569 TKNFERVLGKGGFGTVYHGNLDDT-------------QVAVKMLSHSSAQGYKEFKAEVE 615
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQL 718
L+ +V H HL + G C G ++ EY+E G L + + ++W +M +A +
Sbjct 616 LLLRVHHRHLVGLVGYCDDGDNLALIYEYMEKGDLRENMSGKHSVNVLSWETRMQIAVEA 675
Query 719 ASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVE 774
A L YL N +VH +V NILL A KL+D G+ + E V
Sbjct 676 AQGLEYLHNGCRPPMVHRDVKPTNILLNERSQA-------KLADFGLSRSFPVDGESHVM 728
Query 775 RIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ +L PE N LS D + FG LLEI
Sbjct 729 TVVAGTPGYLDPEYY--RTNWLSEKSDVYSFGVVLLEIV 765
>sp|Q9FLW0|Y5241_ARATH Probable receptor-like protein kinase At5g24010
OS=Arabidopsis thaliana OX=3702 GN=At5g24010 PE=1 SV=1
Length=824
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 61/188 (32%), Positives = 93/188 (49%), Gaps = 14/188 (7%)
Query 938 PQHRSG---WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994
P R G + EI IL + H H++ G CE+Q E + LV EY+ G L+ +L +
Sbjct 521 PGSRQGLPEFLSEITILSKIRHRHLVSLVGYCEEQSE--MILVYEYMDKGPLKSHLYGST 578
Query 995 ---IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ Q L G+ YLH +Q IHRD+ + N+LLDN+ + K+ DFGL+++
Sbjct 579 NPPLSWKQRLEVCIGAARGLHYLHTGSSQGIIHRDIKSTNILLDNNYVAKVADFGLSRSG 638
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
P E + V + PE + + SDV+SFGV L+E+L C P
Sbjct 639 PCIDETH-VSTGVKGSFGYLDPEYFRRQQLTDKSDVYSFGVVLFEVL--CARPAVDPLLV 695
Query 1109 LELIGIAQ 1116
E + +A+
Sbjct 696 REQVNLAE 703
Score = 47.4 bits (111), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 42/158 (27%), Positives = 71/158 (45%), Gaps = 9/158 (6%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK--M 712
F +++S++ H HL + G C E I+V EY++ GPL L + P++WK +
Sbjct 530 FLSEITILSKIRHRHLVSLVGYCEEQSEMILVYEYMDKGPLKSHLYGST-NPPLSWKQRL 588
Query 713 VVAQQLASALSYL---ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
V A L YL ++ ++H ++ NILL +A+ + S P + +S
Sbjct 589 EVCIGAARGLHYLHTGSSQGIIHRDIKSTNILLDNNYVAKVADFGLSRSGPCIDETHVST 648
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+ +L PE L+ D + FG L E+
Sbjct 649 GVK-GSFGYLDPEYFR--RQQLTDKSDVYSFGVVLFEV 683
>sp|Q9M8J5|M2K8_ARATH Mitogen-activated protein kinase kinase
8 OS=Arabidopsis thaliana OX=3702 GN=MKK8 PE=3 SV=2
Length=309
Score = 82.4 bits (202), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 67/217 (31%), Positives = 101/217 (47%), Gaps = 26/217 (12%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
F L +I LG G+ G V + + T E+ A+K +K + S +EI+
Sbjct 46 NTFSVANLDRISVLGSGNGGTV----FKVKDKTTSEIYALKKVKENWD----STSLREIE 97
Query 950 ILRTLYHEHIIKYKGCCED-QGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008
ILR + ++ K ++ GE S+ +M+Y+ LGSL + QL L ++Q+
Sbjct 98 ILRMVNSPYVAKCHDIFQNPSGEVSI--LMDYMDLGSLESL---RGVTEKQLALMSRQVL 152
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE---------GHEYYRVRE 1059
EG YLH +HRD+ N+L + VKI DFG++K V G Y E
Sbjct 153 EGKNYLHEHKIVHRDIKPANLLRSSKEEVKIADFGVSKIVVRSLNKCNSFVGTFAYMSPE 212
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
DS E + YA D+WSFG+T+ E+L
Sbjct 213 RLDSEADGVTEE---DKSNVYAGDIWSFGLTMLEILV 246
>sp|Q9C823|Y1523_ARATH C-type lectin receptor-like tyrosine-protein
kinase At1g52310 OS=Arabidopsis thaliana OX=3702 GN=At1g52310
PE=2 SV=1
Length=552
Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 75/254 (30%), Positives = 120/254 (47%), Gaps = 15/254 (6%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
G VAVK LK Q + + EI LYH +++ KGCC D GE+ +V E++
Sbjct 290 GTKVAVKRLKRS-SFQRKKEFYSEIRRAAKLYHPNVVAIKGCCYDHGERF--IVYEFIAS 346
Query 984 GSLRDYL---PR--HSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDR 1035
G L +L PR S+ L A + +G+A+LH + +HRD+ A NVLLD +
Sbjct 347 GPLDRWLHHVPRGGRSLDWNMRLNIATTLAQGIAFLHDKVKPQVVHRDIRASNVLLDEEF 406
Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+ GL+K VP R G + + APE + + SDV+SFGV L E++
Sbjct 407 GAHLMGVGLSKFVPWEVMQERTVMAGGTYGY-LAPEYVYRNELTTKSDVYSFGVLLLEIV 465
Query 1096 THCDSSQSPPTK--FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE-VYHLMKNCW 1152
+ +Q+ + + + A + R E+L+ P+ C + V L+ +C
Sbjct 466 SGRRPTQAVNSSVGWQSIFEWATPLVQANRWLEILDPVITCGLPEACVVQKVVDLVYSCT 525
Query 1153 ETEASFRPTFENLI 1166
+ S RP +++
Sbjct 526 QNVPSMRPRMSHVV 539
Score = 57.8 bits (138), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 57/198 (29%), Positives = 88/198 (44%), Gaps = 26/198 (13%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L S FY +++ H ++ + G C E +V E++ GPLD
Sbjct 292 KVAVKRLKRSSFQRKKEFYSEIRRAAKLYHPNVVAIKGCCYDHGERFIVYEFIASGPLDR 351
Query 698 WLRRE-RGHVPMAWKM--VVAQQLASALSYLENK---NLVHGNVCGRNILL-----ARLG 746
WL RG + W M +A LA +++L +K +VH ++ N+LL A L
Sbjct 352 WLHHVPRGGRSLDWNMRLNIATTLAQGIAFLHDKVKPQVVHRDIRASNVLLDEEFGAHL- 410
Query 747 LAEGTSPFI---KLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+ G S F+ + + V G +LAPE + N L+T D + FG
Sbjct 411 MGVGLSKFVPWEVMQERTVMAGGT--------YGYLAPEYVY--RNELTTKSDVYSFGVL 460
Query 804 LLEICFDGEAPLQSRSPS 821
LLEI G P Q+ + S
Sbjct 461 LLEI-VSGRRPTQAVNSS 477
>sp|Q8S9L6|CRK29_ARATH Cysteine-rich receptor-like protein kinase
29 OS=Arabidopsis thaliana OX=3702 GN=CRK29 PE=2 SV=1
Length=679
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 68/203 (33%), Positives = 97/203 (48%), Gaps = 16/203 (8%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+LG G FG V + G+ +AVK L + G Q + +K EI +L L H ++++
Sbjct 362 ELGRGGFGSVYKGVFPQ-----GQEIAVKRLSGNSG-QGDNEFKNEILLLAKLQHRNLVR 415
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
G C QGE+ L LV E++ SL ++ R + I G+ YLH
Sbjct 416 LIGFCI-QGEERL-LVYEFIKNASLDQFIFDTEKRQLLDWVVRYKMIGGIARGLLYLHED 473
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECL 1073
IHRDL A N+LLD + KI DFGLAK G +R + APE
Sbjct 474 SRFRIIHRDLKASNILLDQEMNPKIADFGLAKLFDSGQTMTHRFTSRIAGTYGYMAPEYA 533
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
+F +DV+SFGV + E++T
Sbjct 534 MHGQFSVKTDVFSFGVLVIEIIT 556
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 49/190 (26%), Positives = 86/190 (45%), Gaps = 28/190 (15%)
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
+GQE+ V K L + F L++++ H +L + G C++G E ++V E++++
Sbjct 378 QGQEIAV--KRLSGNSGQGDNEFKNEILLLAKLQHRNLVRLIGFCIQGEERLLVYEFIKN 435
Query 693 GPLDVWL----RRERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILL--- 742
LD ++ +R+ + +KM+ +A L YL + ++H ++ NILL
Sbjct 436 ASLDQFIFDTEKRQLLDWVVRYKMIGG--IARGLLYLHEDSRFRIIHRDLKASNILLDQE 493
Query 743 -----ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDK 797
A GLA KL D G + ++APE G S+ T D
Sbjct 494 MNPKIADFGLA-------KLFDSGQTMTHRFTSRIAGTYGYMAPEYAMHGQFSVKT--DV 544
Query 798 WGFGATLLEI 807
+ FG ++EI
Sbjct 545 FSFGVLVIEI 554
>sp|P24583|KPC1_YEAST Protein kinase C-like 1 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PKC1 PE=1
SV=3
Length=1151
Score = 85.9 bits (211), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 70/265 (26%), Positives = 117/265 (44%), Gaps = 28/265 (11%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK---------- 899
T++ Q + + +L++ L P + T + SP T ++ K+
Sbjct 763 TFQIEQDHASKEVLQETVSLAPTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKRRKVSLD 822
Query 900 ----IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH---RSGWKQEIDILR 952
++ LG+G+FGKV L + T + A+K LK D Q+ S ++ L
Sbjct 823 NFVLLKVLGKGNFGKVIL----SKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLL 878
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
+H C Q E + ME++ G L ++ + + + +A ++ +
Sbjct 879 ATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALK 938
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVFWYAP 1070
Y H I+RDL N+LL + +KI D+GL K +Y R +P F AP
Sbjct 939 YFHDNGVIYRDLKLENILLTPEGHIKIADYGLCK----DEMWYGNRTSTFCGTPEF-MAP 993
Query 1071 ECLKEYKFYYASDVWSFGVTLYELL 1095
E LKE ++ A D W+FGV LY++L
Sbjct 994 EILKEQEYTKAVDWWAFGVLLYQML 1018
>sp|Q9WTK7|STK11_MOUSE Serine/threonine-protein kinase STK11 OS=Mus
musculus OX=10090 GN=Stk11 PE=1 SV=1
Length=436
Score = 84.0 bits (206), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 96/198 (48%), Gaps = 6/198 (3%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG +GKV D + +K K P + K+EI +LR L H ++I+
Sbjct 55 LGEGSYGKVK-EVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHRNVIQL 113
Query 963 KGCCEDQGEKSLQLVMEYVPLG--SLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
++ ++ + +VMEY G + D +P + Q + +Q+ +G+ YLH+Q +
Sbjct 114 VDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFRQLIDGLEYLHSQGIV 173
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
H+D+ N+LL + +KI D G+A+A+ R SP F PE +
Sbjct 174 HKDIKPGNLLLTTNGTLKISDLGVAEALHPFAVDDTCRTSQGSPAFQ-PPEIANGLDTFS 232
Query 1080 -YASDVWSFGVTLYELLT 1096
+ D+WS GVTLY + T
Sbjct 233 GFKVDIWSAGVTLYNITT 250
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 56/210 (27%), Positives = 87/210 (41%), Gaps = 15/210 (7%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
MV EY G ++ P+ +QL L YL ++ +VH ++ N+LL
Sbjct 127 MVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFRQLIDGLEYLHSQGIVHKDIKPGNLLLT- 185
Query 745 LGLAEGTSPFIKLSDPGVGLG----ALSREERVER-IPWLAPECLPGGANSLST-AMDKW 798
T+ +K+SD GV A+ R + P P + G ++ S +D W
Sbjct 186 ------TNGTLKISDLGVAEALHPFAVDDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIW 239
Query 799 GFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857
G TL I G P + + + E+ + +P P L+ L L YEP +R
Sbjct 240 SAGVTLYNIT-TGLYPFEGDNIYKLFENIGRGDFTIPCDCGPPLSDLLRGMLEYEPAKRF 298
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
S R I + + H LA+ L P SP +
Sbjct 299 SIRQIRQHSWFRKKHPLAEALVPIPPSPDT 328
>sp|Q9LFG1|Y3359_ARATH Putative leucine-rich repeat receptor-like
serine/threonine-protein kinase At3g53590 OS=Arabidopsis
thaliana OX=3702 GN=At3g53590 PE=1 SV=2
Length=937
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 82/262 (31%), Positives = 120/262 (46%), Gaps = 49/262 (19%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV-FHKRYLKKIRDLGEGHFGKVS 912
T++ FRTI R++ ++ + ++ SD T F L +G G +GKV
Sbjct 584 TKKRVFRTISREIKGVKKFSFVEL---------SDATNGFDSSTL-----IGRGSYGKV- 628
Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972
Y E VA+K + Q + EID+L L+H +++ G D GE+
Sbjct 629 ---YKGILSNKTE-VAIKR-GEETSLQSEKEFLNEIDLLSRLHHRNLVSLIGYSSDIGEQ 683
Query 973 SLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI------CEGMAYLHAQH---YIHRD 1023
LV EY+P G++RD+L S A L F+ + +G+ YLH + IHRD
Sbjct 684 --MLVYEYMPNGNVRDWL---SANAADTLSFSMRSHVALGSAKGILYLHTEANPPVIHRD 738
Query 1024 LAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD----SPVF-----WYAPECLK 1074
+ N+LLD K+ DFGL++ P E DG+ S V + PE
Sbjct 739 IKTSNILLDCQLHAKVADFGLSRLAPAFGE-----GDGEPAHVSTVVRGTPGYLDPEYFM 793
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ SDV+SFGV L ELLT
Sbjct 794 TQQLTVRSDVYSFGVVLLELLT 815
Score = 34.3 bits (77), Expect = 8.8, Method: Compositional matrix adjust.
Identities = 57/237 (24%), Positives = 92/237 (39%), Gaps = 33/237 (14%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMV 713
F L+S++ H +L + G E ++V EY+ +G + WL + + +
Sbjct 655 FLNEIDLLSRLHHRNLVSLIGYSSDIGEQMLVYEYMPNGNVRDWLSANAADTLSFSMRSH 714
Query 714 VAQQLASALSYLE---NKNLVHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPGV 762
VA A + YL N ++H ++ NILL A GL+ F G
Sbjct 715 VALGSAKGILYLHTEANPPVIHRDIKTSNILLDCQLHAKVADFGLSRLAPAF------GE 768
Query 763 GLGALSREERVER-IP-WLAPECLPGGANSLSTAMDKWGFGATLLEIC------FDGEAP 814
G G + V R P +L PE L+ D + FG LLE+ F+G
Sbjct 769 GDGEPAHVSTVVRGTPGYLDPEYF--MTQQLTVRSDVYSFGVVLLELLTGMHPFFEGTHI 826
Query 815 L-QSRSPSEKEHFY----QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
+ + R+ +E R + +LA L C P RP ++++L
Sbjct 827 IREVRTANECGTVLSVADSRMGQCSPDKVKKLAELALWCCEDRPETRPPMSKVVKEL 883
>sp|Q5JK68|CDKC2_ORYSJ Cyclin-dependent kinase C-2 OS=Oryza sativa
subsp. japonica OX=39947 GN=CDKC-2 PE=2 SV=1
Length=513
Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 64/223 (29%), Positives = 106/223 (48%), Gaps = 34/223 (15%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILR 952
+K+ +GEG +G+V + TN E+VA+K ++ D R G+ +EI IL+
Sbjct 25 FEKLEQIGEGTYGQVYMAKETETN----EIVALKKIRMD---NEREGFPITAIREIKILK 77
Query 953 TLYHEHIIKYKGCC-------EDQGEK--------SLQLVMEYVP--LGSLRDYLPRHSI 995
L+H+++I+ K ++QG+ S+ +V EY+ L L D P
Sbjct 78 KLHHQNVIQLKEIVTSPGPERDEQGKPIEGNKYKGSIYMVFEYMDHDLTGLAD-RPGMRF 136
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ Q+ + +Q+ G+ Y H +HRD+ N+L+DN+ +K+ DFGLA++ H
Sbjct 137 TVPQIKCYMRQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSFSSDHNGN 196
Query 1056 RVREDGDSPVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096
WY P L ++ A D+WS G ELL
Sbjct 197 LTNR---VITLWYRPPELLLGSTRYGPAVDMWSVGCIFAELLN 236
>sp|Q0VD22|STK33_BOVIN Serine/threonine-protein kinase 33 OS=Bos
taurus OX=9913 GN=STK33 PE=2 SV=1
Length=486
Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 67/225 (30%), Positives = 104/225 (46%), Gaps = 22/225 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LG+G FG V + D + + V KA G ++E+DIL+++ HEHII
Sbjct 120 RILGQGSFGMV-IEAIDKERETKWAIKKVNKEKA--GSSAVKLLEREVDILKSVKHEHII 176
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019
+ E K + LVME G L++ L R + Q + +AYLH +
Sbjct 177 HLEQVFETP--KKMYLVMELCEDGELKEILERKGHFSENETRWIIQSLASAIAYLHNKDI 234
Query 1020 IHRDLAARNVLLD------NDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
+HRDL N+++ N+ + +K+ DFGLA G ++ +P++ AP
Sbjct 235 VHRDLKLENIMVKSSFIDANNEMNLNIKVTDFGLA-VKKHGRSEVMLQTTCGTPIY-MAP 292
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSS---QSPPTKFLELI 1112
E + + + D+WS GV +Y LL C + S K ELI
Sbjct 293 EVINAHDYSQQCDIWSIGVIMYILL--CGKAPFMASSEEKLFELI 335
Score = 56.2 bits (134), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 54/247 (22%), Positives = 109/247 (44%), Gaps = 23/247 (9%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
++ V H H+ + V + +V E E G L L R +GH + Q LAS
Sbjct 166 ILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILER-KGHFSENETRWIIQSLAS 224
Query 721 ALSYLENKNLVHGNVCGRNILLAR--LGLAEGTSPFIKLSDPGVGLGALSREERVERIP- 777
A++YL NK++VH ++ NI++ + + IK++D G+ + R E + +
Sbjct 225 AIAYLHNKDIVHRDLKLENIMVKSSFIDANNEMNLNIKVTDFGLAVKKHGRSEVMLQTTC 284
Query 778 ----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---- 829
++APE + A+ S D W G ++ I G+AP + S + ++
Sbjct 285 GTPIYMAPEVI--NAHDYSQQCDIWSIGV-IMYILLCGKAPFMASSEEKLFELIKKGELH 341
Query 830 -QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD-------LTRLQPHNLADVLTVN 881
++ + ++ Q + +P R + + +L + ++ +P N+ +++
Sbjct 342 FKNSIWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNTVSSARPTNVLEMMKEW 401
Query 882 PDSPASD 888
++P SD
Sbjct 402 KNNPESD 408
>sp|Q63531|KS6A1_RAT Ribosomal protein S6 kinase alpha-1 OS=Rattus
norvegicus OX=10116 GN=Rps6ka1 PE=1 SV=1
Length=735
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 64/219 (29%), Positives = 112/219 (51%), Gaps = 13/219 (6%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGP 938
V S +DP+ F + ++ LG+G FGKV L T G + A+K LK A
Sbjct 50 VKAGSEKADPSHF-----ELLKVLGQGSFGKVFL-VRKVTRPDNGHLYAMKVLKKATLKV 103
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA 998
+ R K E DIL + H ++K + +G+ L L+++++ G L L + +
Sbjct 104 RDRVRTKMERDILADVNHPFVVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTE 161
Query 999 Q-LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ + + ++ G+ +LH+ I+RDL N+LLD + +K+ DFGL+K E ++ +
Sbjct 162 EDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKK 218
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
V + APE + +++D WS+GV ++E+LT
Sbjct 219 AYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLMFEMLT 257
Score = 62.0 bits (149), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 61/191 (32%), Positives = 90/191 (47%), Gaps = 27/191 (14%)
Query 946 QEIDIL-RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLL 1001
+EI+IL R H +II K +D K + LV E + G L D + R S A +
Sbjct 458 EEIEILLRYGQHPNIITLKDVYDDS--KHVYLVTELMRGGELLDKILRQKFFSEREASFV 515
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRV 1057
L+ I + + YLH+Q +HRDL N+L N ++I DFG AK +
Sbjct 516 LYT--ISKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRA------- 566
Query 1058 REDG--DSPVF---WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE-- 1110
E+G +P + + APE LK + D+WS GV LY +L + P+ E
Sbjct 567 -ENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGYTPFANGPSDTPEEI 625
Query 1111 LIGIAQGQMTV 1121
L I+ G+ T+
Sbjct 626 LTRISSGKFTL 636
>sp|O22187|Y2232_ARATH Probable receptor-like protein kinase At2g23200
OS=Arabidopsis thaliana OX=3702 GN=At2g23200 PE=3 SV=1
Length=834
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 66/202 (33%), Positives = 99/202 (49%), Gaps = 21/202 (10%)
Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G FG Y Y DGT A+K K G Q ++ EI +L + H H++
Sbjct 494 IGKGGFG----YVYKAILPDGTK--AAIKRGKTGSG-QGILEFQTEIQVLSRIRHRHLVS 546
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQ- 1017
G CE+ E + LV E++ G+L+++L S+ Q L G+ YLH+
Sbjct 547 LTGYCEENSE--MILVYEFMEKGTLKEHLYGSNLPSLTWKQRLEICIGAARGLDYLHSSG 604
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECL 1073
IHRD+ + N+LLD + K+ DFGL+K + + G F Y PE L
Sbjct 605 SEGAIIHRDVKSTNILLDEHNIAKVADFGLSKIHNQDESNISINIKG---TFGYLDPEYL 661
Query 1074 KEYKFYYASDVWSFGVTLYELL 1095
+ +K SDV++FGV L E+L
Sbjct 662 QTHKLTEKSDVYAFGVVLLEVL 683
Score = 54.7 bits (130), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 61/243 (25%), Positives = 99/243 (41%), Gaps = 40/243 (16%)
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP-MAWK 711
L F ++S++ H HL + G C E I+V E++E G L L ++P + WK
Sbjct 527 LEFQTEIQVLSRIRHRHLVSLTGYCEENSEMILVYEFMEKGTLKEHLY--GSNLPSLTWK 584
Query 712 --MVVAQQLASALSYLENKN----LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+ + A L YL + ++H +V NILL +A K++D G+
Sbjct 585 QRLEICIGAARGLDYLHSSGSEGAIIHRDVKSTNILLDEHNIA-------KVADFGLSKI 637
Query 766 ALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF-----DGEAPL 815
E + +L PE L + L+ D + FG LLE+ F D P
Sbjct 638 HNQDESNISINIKGTFGYLDPEYLQ--THKLTEKSDVYAFGVVLLEVLFARPAIDPYLPH 695
Query 816 QSRSPSEKEHFYQRQHRLPE------------PSCPQLATLTSQCLTYEPTQRPSFRTIL 863
+ + SE F + + + E S + + +CL +RPS R ++
Sbjct 696 EEVNLSEWVMFCKSKGTIDEILDPSLIGQIETNSLKKFMEIAEKCLKEYGDERPSMRDVI 755
Query 864 RDL 866
DL
Sbjct 756 WDL 758
>sp|Q9SXB5|Y1135_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g11303 OS=Arabidopsis thaliana OX=3702
GN=At1g11303 PE=3 SV=1
Length=820
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 86/282 (30%), Positives = 124/282 (44%), Gaps = 34/282 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG P G G+ +AVK L G Q E+ ++ L H ++
Sbjct 515 LGQGGFG--------PVYKGMLLEGQEIAVKRLSQASG-QGLEELVTEVVVISKLQHRNL 565
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLF--AQQICEGMAYLH 1015
+K GCC E+ LV E++P SL Y+ PR + L F IC G+ YLH
Sbjct 566 VKLFGCCIAGEER--MLVYEFMPKKSLDFYIFDPREAKLLDWNTRFEIINGICRGLLYLH 623
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
IHRDL A N+LLD + + KI DFGLA+ P + R + + APE
Sbjct 624 RDSRLRIIHRDLKASNILLDENLIPKISDFGLARIFPGNEDEANTRRVVGT-YGYMAPEY 682
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI---GIAQGQMTVLRLTELLE 1129
F SDV+S GV L E+++ +S S + I G G + +L E
Sbjct 683 AMGGLFSEKSDVFSLGVILLEIISGRRNSHSTLLAHVWSIWNEGEINGMVDPEIFDQLFE 742
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ R KC H+ C + A+ RP+ + +L +
Sbjct 743 KEIR-----KC----VHIALLCVQDAANDRPSVSTVCMMLSS 775
Score = 41.6 bits (96), Expect = 0.053, Method: Compositional matrix adjust.
Identities = 41/158 (26%), Positives = 69/158 (44%), Gaps = 20/158 (13%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQL 718
++S++ H +L + G C+ G E ++V E++ LD ++ R + W + + +
Sbjct 556 VISKLQHRNLVKLFGCCIAGEERMLVYEFMPKKSLDFYIFDPREAKLLDWNTRFEIINGI 615
Query 719 ASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERV 773
L YL + ++H ++ NIL L E P K+SD G+ E
Sbjct 616 CRGLLYLHRDSRLRIIHRDLKASNIL-----LDENLIP--KISDFGLARIFPGNEDEANT 668
Query 774 ERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
R+ ++APE GG S D + G LLEI
Sbjct 669 RRVVGTYGYMAPEYAMGGL--FSEKSDVFSLGVILLEI 704
>sp|P43294|MHK_ARATH Serine/threonine-protein kinase MHK OS=Arabidopsis
thaliana OX=3702 GN=MHK PE=2 SV=2
Length=443
Score = 84.0 bits (206), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 70/211 (33%), Positives = 96/211 (45%), Gaps = 21/211 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
VF K + +LG+G G V Y N T E+VAVK +K +E+
Sbjct 5 VVFVMCRYKILEELGDGTCGSV----YKAVNLETYEVVAVKKMKRKFYYWEECVNLREVK 60
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQIC 1008
LR L H HIIK K + E L + E + R ++ F Q+
Sbjct 61 ALRKLNHPHIIKLKEIVREHNE--LFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQML 118
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV---PEGHEYYRVREDGDSPV 1065
+G+A++H Y HRDL N+L+ N+ ++KI DFGLA+ V P EY R
Sbjct 119 QGLAHMHKNGYFHRDLKPENLLVTNN-ILKIADFGLAREVASMPPYTEYVSTR------- 170
Query 1066 FWY-APECLKEYKFYY-ASDVWSFGVTLYEL 1094
WY APE L + Y A D+W+ G L EL
Sbjct 171 -WYRAPEVLLQSSLYTPAVDMWAVGAILAEL 200
>sp|Q6DE87|CHK1_XENLA Serine/threonine-protein kinase Chk1 OS=Xenopus
laevis OX=8355 GN=chek1 PE=1 SV=2
Length=474
Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 73/204 (36%), Positives = 103/204 (50%), Gaps = 21/204 (10%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK----ADCGPQHRSGWKQEIDILRTLY 955
++ LGEG +G+V L N T E VAVK + ADC P++ K+EI I R L
Sbjct 12 VQTLGEGAYGEVQL----AVNRKTEEAVAVKIVDMTRAADC-PEN---IKKEICINRMLS 63
Query 956 HEHIIKYKGCCEDQGEKSLQ-LVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAY 1013
H +I+++ G + E ++Q L +EY G L D + P + F QQ+ G+ Y
Sbjct 64 HTNIVRFYG---HRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEY 120
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPEC 1072
LH+ HRD+ N+LLD +KI DFGLA G E + G P + APE
Sbjct 121 LHSIGITHRDIKPENLLLDERDQLKISDFGLATVFRHNGKERLLNKMCGTLP--YVAPEL 178
Query 1073 LKEYKFYYA-SDVWSFGVTLYELL 1095
+K F+ DVWS G+ L +L
Sbjct 179 IKSRAFHADPVDVWSCGIVLTAML 202
Score = 36.6 bits (83), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 71/295 (24%), Positives = 119/295 (40%), Gaps = 36/295 (12%)
Query 632 DRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
+R E V +K++D + D + + +SHT++ +G G + EY
Sbjct 28 NRKTEEAVAVKIVDMTRAADCPENIKKEICINRMLSHTNIVRFYGHRREGNIQYLFLEYC 87
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L + + G +P QQL + + YL + + H ++ N+LL
Sbjct 88 RGGELFDRIEPDVG-MPEQDAQKFFQQLIAGVEYLHSIGITHRDIKPENLLL-------D 139
Query 751 TSPFIKLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGA 802
+K+SD GL + R ER +P++APE + A + +D W G
Sbjct 140 ERDQLKISD--FGLATVFRHNGKERLLNKMCGTLPYVAPELIKSRAFH-ADPVDVWSCGI 196
Query 803 TLLEICFDGEAPLQSRSPSEKEH--FYQRQHRL---PEPSCPQLATLTSQCLTYEPTQRP 857
L + GE P + +E+ + ++ H L + S LA L + LT P R
Sbjct 197 VLTAM-LAGELPWDQPNEVCQEYCDWKEKNHYLTPWKKISATPLA-LLCKMLTENPQSRI 254
Query 858 SFRTILRD--LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR-DLGEGHFG 909
+ I +D T + L ++ S SD +V K+IR D+ HF
Sbjct 255 TIPDIKKDRWFTEIIKKGLKRSRVISGGS--SDSSVL----CKQIRSDIDISHFS 303
>sp|Q66HE5|NUAK2_RAT NUAK family SNF1-like kinase 2 OS=Rattus
norvegicus OX=10116 GN=Nuak2 PE=1 SV=1
Length=630
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 71/233 (30%), Positives = 109/233 (47%), Gaps = 22/233 (9%)
Query 874 LADVLTVNPDSPASDPTV---FHKRYLKK----IRDLGEGHFGKVSLYCYDPTNDGTGEM 926
LAD L +P V HK L+ + LG+G +GKV + +G +
Sbjct 27 LADRLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVK-----KARESSGRL 81
Query 927 VAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
VA+K+++ D Q ++EI+I+ +L H HII E+ + + +VMEY G
Sbjct 82 VAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVFENSSK--IVIVMEYASRG 139
Query 985 SLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
L DY+ R + F +QI + Y H +HRDL N+LLD +KI DFG
Sbjct 140 DLYDYISERPRLNERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDASGNIKIADFG 199
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELL 1095
L+ H+ ++ SP++ +PE + + D WS GV LY L+
Sbjct 200 LSNLY---HKGKFLQTFCGSPLY-ASPEIVNGKPYVGPEVDSWSLGVLLYILV 248
Score = 41.6 bits (96), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 42/159 (26%), Positives = 66/159 (42%), Gaps = 15/159 (9%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
+MS ++H H+ +H V + ++V EY G L ++ ER + +Q+ S
Sbjct 107 IMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYI-SERPRLNERDARHFFRQIVS 165
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---- 776
AL Y +VH ++ NILL G IK++D GL L + + +
Sbjct 166 ALHYCHQNGIVHRDLKLENILLDASG-------NIKIAD--FGLSNLYHKGKFLQTFCGS 216
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
P A + G + +D W G LL I G P
Sbjct 217 PLYASPEIVNGKPYVGPEVDSWSLG-VLLYILVHGTMPF 254
>sp|Q5JLD8|CIPK8_ORYSJ CBL-interacting protein kinase 8 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK8 PE=2 SV=1
Length=446
Score = 84.0 bits (206), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 62/200 (31%), Positives = 102/200 (51%), Gaps = 13/200 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG--WKQEIDILRTLYHEH 958
R +GEG F KV N +GE VA+K + +H+ K+EI I++ + H +
Sbjct 17 RTIGEGTFAKVKF----AQNTESGESVAMKVVDRSSILKHKMADQIKREISIMKLVRHPN 72
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQ 1017
+++ + K + +++E++ G L D + RH + A + QQ+ +G+ + H++
Sbjct 73 VVRLHEVLASR--KKIFIILEFITGGELFDKIIRHGRLNEADARRYFQQLIDGVDFCHSK 130
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
HRDL N+LLD+ +KI DFGL+ +G +R +P + APE L
Sbjct 131 GVYHRDLKPENLLLDSQGNLKISDFGLSAWPAQGGAL--LRTTCGTPNY-VAPEVLSHKG 187
Query 1078 FYYA-SDVWSFGVTLYELLT 1096
+ A +D WS GV LY LL
Sbjct 188 YDGALADTWSCGVILYVLLA 207
Score = 36.2 bits (82), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 20/175 (11%)
Query 639 VVLKVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +KV+D S H +A S+M V H ++ +H V + ++ E++ G L
Sbjct 39 VAMKVVDRSSILKHKMADQIKREISIMKLVRHPNVVRLHEVLASRKKIFIILEFITGGEL 98
Query 696 -DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
D +R R + A + QQL + + +K + H ++ N+LL G
Sbjct 99 FDKIIRHGRLNEADARRYF--QQLIDGVDFCHSKGVYHRDLKPENLLLDSQG-------N 149
Query 755 IKLSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+K+SD G+ GAL R ++APE L + A D W G L
Sbjct 150 LKISDFGLSAWPAQGGALLRTT-CGTPNYVAPEVLSHKGYDGALA-DTWSCGVIL 202
>sp|Q5R8Z4|PAK6_PONAB Serine/threonine-protein kinase PAK 6 OS=Pongo
abelii OX=9601 GN=PAK6 PE=2 SV=1
Length=681
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 63/213 (30%), Positives = 105/213 (49%), Gaps = 24/213 (11%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP + Y+K +GEG G V L +G VAVK + Q R E
Sbjct 402 DPRLLLDSYVK----IGEGSTGIVCLA----REKHSGRQVAVKMMDLRKQ-QRRELLFNE 452
Query 948 IDILRTLYHEHIIK-YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006
+ I+R H ++++ YK GE+ L ++ME++ G+L D + + + Q+ +
Sbjct 453 VVIMRDYQHFNVVEMYKSYLV--GEE-LWVLMEFLQGGALTDIVSQVRLNEEQIATVCEA 509
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG----LAKAVPEGHEYYRVREDGD 1062
+ + +AYLHAQ IHRD+ + ++LL D VK+ DFG ++K VP+ R+
Sbjct 510 VLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPK-------RKSLV 562
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+W APE + + D+WS G+ + E++
Sbjct 563 GTPYWMAPEVISRSLYATEVDIWSLGIMVIEMV 595
Score = 47.4 bits (111), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 56/246 (23%), Positives = 105/246 (43%), Gaps = 28/246 (11%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
R++ +V +K++D + +M H ++ ++ + G E ++ E+
Sbjct 424 AREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELWVLMEF 483
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
++ G L + + R + V + + AL+YL + ++H ++ +ILL G
Sbjct 484 LQGGALTDIVSQVRLNEEQI--ATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGR-- 539
Query 750 GTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSL-STAMDKWGFGATL 804
+KLSD G + R+ V W+APE + + SL +T +D W G +
Sbjct 540 -----VKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVI---SRSLYATEVDIWSLGIMV 591
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------CPQLATLTSQCLTYEPTQRP 857
+E+ DGE P S SP + +R P P P L + L +P +R
Sbjct 592 IEMV-DGEPPYFSDSPVQA---MKRLRDSPPPKLKNSHKVSPVLRDFLERMLVRDPQERA 647
Query 858 SFRTIL 863
+ + +L
Sbjct 648 TAQELL 653
>sp|Q64303|PAK2_RAT Serine/threonine-protein kinase PAK 2 OS=Rattus
norvegicus OX=10116 GN=Pak2 PE=1 SV=1
Length=524
Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 60/209 (29%), Positives = 100/209 (48%), Gaps = 16/209 (8%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP + RY K +G+G G V + T+ G+ VA+K + P+ + E
Sbjct 244 DPKKKYTRYEK----IGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINE 294
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +++ L + +I+ + E L +VMEY+ GSL D + + AQ+ ++
Sbjct 295 ILVMKELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCREC 352
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066
+ + +LHA IHRD+ + NVLL + VK+ DFG A+ PE + R +
Sbjct 353 LQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 408
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095
W APE + + D+WS G+ E++
Sbjct 409 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 437
Score = 37.4 bits (85), Expect = 0.82, Method: Compositional matrix adjust.
Identities = 49/215 (23%), Positives = 90/215 (42%), Gaps = 26/215 (12%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719
+M ++ + ++ + G E +V EY+ G L DV +A V ++
Sbjct 297 VMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIA---AVCRECL 353
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777
AL +L ++H ++ N+LL EG+ +KL+D G A E+ +R
Sbjct 354 QALEFLHANQVIHRDIKSDNVLLG----MEGS---VKLTD--FGFCAQITPEQSKRSTMV 404
Query 778 ----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---- 829
W+APE + A +D W G +E+ +GE P + +P +
Sbjct 405 GTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNGTP 461
Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ + PE P ++CL + +R S + +L+
Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496
>sp|Q9NQU5|PAK6_HUMAN Serine/threonine-protein kinase PAK 6 OS=Homo
sapiens OX=9606 GN=PAK6 PE=1 SV=1
Length=681
Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 63/213 (30%), Positives = 105/213 (49%), Gaps = 24/213 (11%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP + Y+K +GEG G V L +G VAVK + Q R E
Sbjct 402 DPRLLLDSYVK----IGEGSTGIVCLA----REKHSGRQVAVKMMDLRKQ-QRRELLFNE 452
Query 948 IDILRTLYHEHIIK-YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006
+ I+R H ++++ YK GE+ L ++ME++ G+L D + + + Q+ +
Sbjct 453 VVIMRDYQHFNVVEMYKSYLV--GEE-LWVLMEFLQGGALTDIVSQVRLNEEQIATVCEA 509
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG----LAKAVPEGHEYYRVREDGD 1062
+ + +AYLHAQ IHRD+ + ++LL D VK+ DFG ++K VP+ R+
Sbjct 510 VLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPK-------RKSLV 562
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+W APE + + D+WS G+ + E++
Sbjct 563 GTPYWMAPEVISRSLYATEVDIWSLGIMVIEMV 595
Score = 47.4 bits (111), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 56/246 (23%), Positives = 105/246 (43%), Gaps = 28/246 (11%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
R++ +V +K++D + +M H ++ ++ + G E ++ E+
Sbjct 424 AREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELWVLMEF 483
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
++ G L + + R + V + + AL+YL + ++H ++ +ILL G
Sbjct 484 LQGGALTDIVSQVRLNEEQI--ATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGR-- 539
Query 750 GTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSL-STAMDKWGFGATL 804
+KLSD G + R+ V W+APE + + SL +T +D W G +
Sbjct 540 -----VKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVI---SRSLYATEVDIWSLGIMV 591
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------CPQLATLTSQCLTYEPTQRP 857
+E+ DGE P S SP + +R P P P L + L +P +R
Sbjct 592 IEMV-DGEPPYFSDSPVQA---MKRLRDSPPPKLKNSHKVSPVLRDFLERMLVRDPQERA 647
Query 858 SFRTIL 863
+ + +L
Sbjct 648 TAQELL 653
>sp|Q6FV07|IPL1_CANGA Spindle assembly checkpoint kinase OS=Candida
glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC
0622 / NRRL Y-65 / CBS 138) OX=284593 GN=IPL1 PE=3 SV=1
Length=358
Score = 82.8 bits (203), Expect = 2e-15, Method: Composition-based stats.
Identities = 76/249 (31%), Positives = 127/249 (51%), Gaps = 27/249 (11%)
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDP----TVFHKRYLKKI---RDLGEGHFGKVS 912
R L++ R +P ++ + ++P+S + T +K LK R LG+G FGKV
Sbjct 57 RLFLKNQER-KPLGVSPLSNLSPNSLGRNSLEKSTYNNKLSLKDFEVGRKLGKGKFGKV- 114
Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGCCEDQG 970
YC + +G + A+KA++ + Q K+E+DI + H +IIK D
Sbjct 115 -YCV--RHKKSGFICALKAIEKNEILQFNLLKQLKREVDIQLGMDHPNIIKLYAHFHD-- 169
Query 971 EKSLQLVMEYVPLG----SLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
EK + L+ME+ G SL++ P + + LA ++ QI + + Y+H + IHRD+
Sbjct 170 EKRVYLLMEHSINGELYKSLKNNGPFNDV-LASHYIY--QIADALHYMHKKRIIHRDVKP 226
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
NVL+ D +VK+ DFG + PEG + R+ + + +PE + ++ DVW+
Sbjct 227 ENVLIGFDNVVKLADFGWSILNPEGSK----RKTLCGTIDYLSPEMITPREYDEQVDVWA 282
Query 1087 FGVTLYELL 1095
GV YEL+
Sbjct 283 LGVLAYELV 291
Score = 39.7 bits (91), Expect = 0.14, Method: Composition-based stats.
Identities = 40/150 (27%), Positives = 61/150 (41%), Gaps = 20/150 (13%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---GALSREERV 773
Q+A AL Y+ K ++H +V N+L+ G +KL+D G + R+
Sbjct 206 QIADALHYMHKKRIIHRDVKPENVLI-------GFDNVVKLADFGWSILNPEGSKRKTLC 258
Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR- 832
I +L+PE + +D W G E+ G P + S KE Y+R +
Sbjct 259 GTIDYLSPEMIT--PREYDEQVDVWALGVLAYELVV-GVPPFEENS---KELTYKRILKC 312
Query 833 ---LPEPSCPQLATLTSQCLTYEPTQRPSF 859
PE L S+ L + TQR S
Sbjct 313 DLNFPESISKDAKDLISKLLVTDTTQRLSL 342
>sp|Q6P9R2|OXSR1_MOUSE Serine/threonine-protein kinase OSR1 OS=Mus
musculus OX=10090 GN=Oxsr1 PE=1 SV=1
Length=527
Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 61/200 (31%), Positives = 97/200 (49%), Gaps = 15/200 (8%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
E VA+K + + +EI + +H +I+ Y + E L LVM+ + G
Sbjct 41 ERVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGG 98
Query 985 SLRDYLP------RHSIGLAQ---LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035
S+ D + H G+ + +++ EG+ YLH IHRD+ A N+LL D
Sbjct 99 SVLDIIKHIVAKGEHKSGVLDEPTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG 158
Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092
V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T
Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAI 218
Query 1093 ELLTHCDS-SQSPPTKFLEL 1111
EL T + PP K L L
Sbjct 219 ELATGAAPYHKYPPMKVLML 238
Score = 37.7 bits (86), Expect = 0.73, Method: Compositional matrix adjust.
Identities = 42/169 (25%), Positives = 66/169 (39%), Gaps = 23/169 (14%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALS 768
+ +++ L YL +H +V NILL G + G S F L+ G
Sbjct 125 TILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAF--LATGGDITRNKV 182
Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------L 815
R+ V W+APE + D W FG T +E+ G AP L
Sbjct 183 RKTFVGTPCWMAPEVME-QVRGYDFKADIWSFGITAIELA-TGAAPYHKYPPMKVLMLTL 240
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
Q+ PS + ++ + + + S CL +P +RP+ +LR
Sbjct 241 QNDPPSLETGVQDKE--MLKKYGKSFRKMISLCLQKDPEKRPTAAELLR 287
>sp|A0A8I5ZNK2|OXSR1_RAT Serine/threonine-protein kinase OSR1
OS=Rattus norvegicus OX=10116 GN=Oxsr1 PE=1 SV=1
Length=528
Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 61/200 (31%), Positives = 98/200 (49%), Gaps = 15/200 (8%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
E VA+K + + +EI + +H +I+ Y + E L LVM+ + G
Sbjct 41 ERVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGG 98
Query 985 SLRDYLP------RHSIGL---AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035
S+ D + H G+ + + +++ EG+ YLH IHRD+ A N+LL D
Sbjct 99 SVLDIIKHIVAKGEHKGGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG 158
Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092
V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T
Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAI 218
Query 1093 ELLTHCDS-SQSPPTKFLEL 1111
EL T + PP K L L
Sbjct 219 ELATGAAPYHKYPPMKVLML 238
Score = 37.4 bits (85), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 42/169 (25%), Positives = 65/169 (38%), Gaps = 23/169 (14%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALS 768
+ +++ L YL +H +V NILL G + G S F L+ G
Sbjct 125 TILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAF--LATGGDITRNKV 182
Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------L 815
R+ V W+APE + D W FG T +E+ G AP L
Sbjct 183 RKTFVGTPCWMAPEVME-QVRGYDFKADIWSFGITAIELA-TGAAPYHKYPPMKVLMLTL 240
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
Q+ PS ++ + + + S CL +P +RP+ +LR
Sbjct 241 QNDPPSLDTGVQDKE--MLKKYGKSFRKMISLCLQKDPEKRPTAAELLR 287
>sp|Q6I5Y0|CDKC1_ORYSJ Cyclin-dependent kinase C-1 OS=Oryza sativa
subsp. japonica OX=39947 GN=CDKC-1 PE=2 SV=1
Length=519
Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 65/223 (29%), Positives = 105/223 (47%), Gaps = 34/223 (15%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILR 952
+K+ +GEG +G+V Y T E+VA+K ++ D R G+ +EI IL+
Sbjct 25 FEKLEQIGEGTYGQV----YMARETETQEIVALKKIRMD---NEREGFPITAIREIKILK 77
Query 953 TLYHEHIIKYKGCC-------EDQGEK--------SLQLVMEYVP--LGSLRDYLPRHSI 995
L+H+++I+ K ++QG+ S+ +V EY+ L L D P
Sbjct 78 KLHHQNVIQLKEIVTSPGPERDEQGKPIHGNKYKGSIYMVFEYMDHDLTGLAD-RPGMRF 136
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ Q+ + +Q+ G+ Y H +HRD+ N+L+DN+ +K+ DFGLA++ H
Sbjct 137 TVPQIKCYMKQLLTGLHYCHINQVLHRDIKGSNLLIDNEGNLKLADFGLARSFSNDHNGN 196
Query 1056 RVREDGDSPVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096
WY P L K+ A D+WS G ELL
Sbjct 197 LTNR---VITLWYRPPELLLGSTKYGPAVDMWSVGCIFAELLN 236
>sp|Q8GUH1|PUB33_ARATH U-box domain-containing protein 33 OS=Arabidopsis
thaliana OX=3702 GN=PUB33 PE=2 SV=2
Length=834
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 64/202 (32%), Positives = 95/202 (47%), Gaps = 21/202 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG +G + + T VA+K L + Q ++QE+D+L + H +II
Sbjct 487 IGEGGYGSIYVGLLRHTQ------VAIKMLNPNSS-QGPVEYQQEVDVLSKMRHPNIITL 539
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLH--- 1015
G C + LV EY+P GSL D L + + A +IC + +LH
Sbjct 540 IGACPE----GWSLVYEYLPGGSLEDRLTCKDNSPPLSWQNRVRIATEICAALVFLHSNK 595
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLK 1074
A +H DL N+LLD++ + K+ DFG + P G + VR D V + PE
Sbjct 596 AHSLVHGDLKPANILLDSNLVSKLSDFGTCSLLHPNGSK--SVRTDVTGTVAYLDPEASS 653
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ SDV+SFG+ L LLT
Sbjct 654 SGELTPKSDVYSFGIILLRLLT 675
Score = 49.3 bits (116), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 49/181 (27%), Positives = 89/181 (49%), Gaps = 22/181 (12%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K+L+P+ + + + ++S++ H ++ + G C G +V EY+ G L+
Sbjct 504 QVAIKMLNPNSSQGPVEYQQEVDVLSKMRHPNIITLIGACPEGWS--LVYEYLPGGSLED 561
Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYL-ENK--NLVHGNVCGRNILLARLGLAEGTS 752
L + P++W ++ +A ++ +AL +L NK +LVHG++ NILL ++
Sbjct 562 RLTCKDNSPPLSWQNRVRIATEICAALVFLHSNKAHSLVHGDLKPANILL-------DSN 614
Query 753 PFIKLSDPGVGL-----GALS-REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
KLSD G G+ S R + + +L PE G L+ D + FG LL
Sbjct 615 LVSKLSDFGTCSLLHPNGSKSVRTDVTGTVAYLDPEASSSG--ELTPKSDVYSFGIILLR 672
Query 807 I 807
+
Sbjct 673 L 673
>sp|C0LGG9|Y5344_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g53440 OS=Arabidopsis thaliana OX=3702
GN=At1g53440 PE=2 SV=2
Length=1035
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 78/285 (27%), Positives = 125/285 (44%), Gaps = 35/285 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG V G +AVK L + +R + EI ++ L H +++K
Sbjct 673 IGEGGFGPVYKGVL-----ADGMTIAVKQLSSKSKQGNRE-FVTEIGMISALQHPNLVKL 726
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLR-------------DYLPRHSIGLAQLLLFAQQICE 1009
GCC + K L LV EY+ SL D+ R+ + + I +
Sbjct 727 YGCCIEG--KELLLVYEYLENNSLARALFGTEKQRLHLDWSTRNKVCIG--------IAK 776
Query 1010 GMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G+AYLH + +HRD+ A NVLLD KI DFGLAK E + + R G +
Sbjct 777 GLAYLHEESRLKIVHRDIKATNVLLDLSLNAKISDFGLAKLDEEENTHISTRIAG--TIG 834
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+ APE +DV+SFGV E+++ +++ P +F+ L+ A L
Sbjct 835 YMAPEYAMRGYLTDKADVYSFGVVCLEIVSGKSNTNYRPKEEFIYLLDWAYVLQEQGSLL 894
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
EL++ K + ++ C + RP +++ +L+
Sbjct 895 ELVDPDLGTSFSKKEAMRMLNIALLCTNPSPTLRPPMSSVVSMLQ 939
Score = 58.2 bits (139), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 70/270 (26%), Positives = 111/270 (41%), Gaps = 48/270 (18%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+ + +K L F ++S + H +L ++G C+ G E ++V EY+E+ L
Sbjct 690 MTIAVKQLSSKSKQGNREFVTEIGMISALQHPNLVKLYGCCIEGKELLLVYEYLENNSLA 749
Query 697 VWL---RRERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEG 750
L ++R H+ + + V +A L+YL ++ +VH ++ N+LL L L
Sbjct 750 RALFGTEKQRLHLDWSTRNKVCIGIAKGLAYLHEESRLKIVHRDIKATNVLL-DLSLNAK 808
Query 751 TSPFIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGAT 803
S F GL L EE I ++APE G L+ D + FG
Sbjct 809 ISDF--------GLAKLDEEENTHISTRIAGTIGYMAPEYAMRGY--LTDKADVYSFGVV 858
Query 804 LLEICFDGEAPLQSRSPSEK-------EHFYQRQHRLPEPSCPQLATLTSQ--------- 847
LEI G++ R P E+ + Q Q L E P L T S+
Sbjct 859 CLEIV-SGKSNTNYR-PKEEFIYLLDWAYVLQEQGSLLELVDPDLGTSFSKKEAMRMLNI 916
Query 848 ---CLTYEPTQRP---SFRTILRDLTRLQP 871
C PT RP S ++L+ ++QP
Sbjct 917 ALLCTNPSPTLRPPMSSVVSMLQGKIKVQP 946
>sp|Q8CIN4|PAK2_MOUSE Serine/threonine-protein kinase PAK 2 OS=Mus
musculus OX=10090 GN=Pak2 PE=1 SV=1
Length=524
Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 60/209 (29%), Positives = 100/209 (48%), Gaps = 16/209 (8%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP + RY K +G+G G V + T+ G+ VA+K + P+ + E
Sbjct 244 DPKKKYTRYEK----IGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINE 294
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +++ L + +I+ + E L +VMEY+ GSL D + + AQ+ ++
Sbjct 295 ILVMKELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCREC 352
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066
+ + +LHA IHRD+ + NVLL + VK+ DFG A+ PE + R +
Sbjct 353 LQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 408
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095
W APE + + D+WS G+ E++
Sbjct 409 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 437
Score = 37.4 bits (85), Expect = 0.84, Method: Compositional matrix adjust.
Identities = 49/215 (23%), Positives = 90/215 (42%), Gaps = 26/215 (12%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719
+M ++ + ++ + G E +V EY+ G L DV +A V ++
Sbjct 297 VMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIA---AVCRECL 353
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777
AL +L ++H ++ N+LL EG+ +KL+D G A E+ +R
Sbjct 354 QALEFLHANQVIHRDIKSDNVLLG----MEGS---VKLTD--FGFCAQITPEQSKRSTMV 404
Query 778 ----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---- 829
W+APE + A +D W G +E+ +GE P + +P +
Sbjct 405 GTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNGTP 461
Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ + PE P ++CL + +R S + +L+
Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496
>sp|Q9FX99|Y1497_ARATH Probable receptor-like protein kinase At1g49730
OS=Arabidopsis thaliana OX=3702 GN=At1g49730 PE=2 SV=1
Length=663
Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 64/203 (32%), Positives = 102/203 (50%), Gaps = 19/203 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FG V + NDG + AVK + Q + +EI +L L+H +++
Sbjct 333 IGQGGFGTVYKAEF---NDGL--IAAVKKMNK-VSEQAEQDFCREIGLLAKLHHRNLVAL 386
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL-----AQLLLFAQQICEGMAYLHAQ 1017
KG C ++ E+ L V +Y+ GSL+D+L H+IG + A + + YLH
Sbjct 387 KGFCINKKERFL--VYDYMKNGSLKDHL--HAIGKPPPSWGTRMKIAIDVANALEYLHFY 442
Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR-VREDGDSPVFWYAPECL 1073
HRD+ + N+LLD + + K+ DFGLA + +G + V D + PE +
Sbjct 443 CDPPLCHRDIKSSNILLDENFVAKLSDFGLAHSSRDGSVCFEPVNTDIRGTPGYVDPEYV 502
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
+ SDV+S+GV L EL+T
Sbjct 503 VTQELTEKSDVYSYGVVLLELIT 525
>sp|Q29502|PAK2_RABIT Serine/threonine-protein kinase PAK 2 OS=Oryctolagus
cuniculus OX=9986 GN=PAK2 PE=1 SV=1
Length=524
Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 60/209 (29%), Positives = 100/209 (48%), Gaps = 16/209 (8%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP + RY K +G+G G V + T+ G+ VA+K + P+ + E
Sbjct 244 DPKKKYTRYEK----IGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINE 294
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +++ L + +I+ + E L +VMEY+ GSL D + + AQ+ ++
Sbjct 295 ILVMKELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCREC 352
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066
+ + +LHA IHRD+ + NVLL + VK+ DFG A+ PE + R +
Sbjct 353 LQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 408
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095
W APE + + D+WS G+ E++
Sbjct 409 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 437
Score = 37.4 bits (85), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 49/215 (23%), Positives = 90/215 (42%), Gaps = 26/215 (12%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719
+M ++ + ++ + G E +V EY+ G L DV +A V ++
Sbjct 297 VMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIA---AVCRECL 353
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777
AL +L ++H ++ N+LL EG+ +KL+D G A E+ +R
Sbjct 354 QALEFLHANQVIHRDIKSDNVLLG----MEGS---VKLTD--FGFCAQITPEQSKRSTMV 404
Query 778 ----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---- 829
W+APE + A +D W G +E+ +GE P + +P +
Sbjct 405 GTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNGTP 461
Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ + PE P ++CL + +R S + +L+
Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496
>sp|Q4P5N0|STE20_USTMA Serine/threonine-protein kinase SMU1 OS=Ustilago
maydis (strain 521 / FGSC 9021) OX=237631 GN=SMU1
PE=3 SV=1
Length=746
Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 60/209 (29%), Positives = 104/209 (50%), Gaps = 14/209 (7%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
+DPT + R L+KI G+G G V + GT VA+K + + P+ +
Sbjct 466 ADPTKLY-RSLQKI---GQGASGGV----FTAYQVGTNVSVAIKQMNLEQQPK-KDLIIN 516
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006
EI +++ H +I+ + +G+ L +VMEY+ GSL D + + + Q+ +++
Sbjct 517 EILVMKESRHRNIVNFIDSFLFKGD--LWVVMEYMEGGSLTDVVTCNIMTEGQIAAVSRE 574
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+ EG+ +LH IHRD+ + NVLL +K+ DFG + E + R G +
Sbjct 575 VLEGLRHLHQHGVIHRDIKSDNVLLSLQGDIKLTDFGFCAQIGES-QAKRTTMVGTP--Y 631
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095
W APE + ++ D+WS G+ E++
Sbjct 632 WMAPEVVTRKEYGPKVDIWSLGIMCIEMV 660
Score = 34.3 bits (77), Expect = 9.1, Method: Compositional matrix adjust.
Identities = 39/168 (23%), Positives = 71/168 (42%), Gaps = 24/168 (14%)
Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLR---RERGHVPMAWKMVVAQ 716
+M + H ++ F+ +G + +V EY+E G L + G + V++
Sbjct 520 VMKESRHRNIVNFIDSFLFKG-DLWVVMEYMEGGSLTDVVTCNIMTEGQI-----AAVSR 573
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREER 772
++ L +L ++H ++ N+LL+ G IKL+D G +G R
Sbjct 574 EVLEGLRHLHQHGVIHRDIKSDNVLLSLQG-------DIKLTDFGFCAQIGESQAKRTTM 626
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
V W+APE + +D W G +E+ +GE P + +P
Sbjct 627 VGTPYWMAPEVV--TRKEYGPKVDIWSLGIMCIEMV-EGEPPYLNENP 671
>sp|Q7RAH3|CDPK1_PLAYO Calcium-dependent protein kinase 1 OS=Plasmodium
yoelii yoelii OX=73239 GN=CDPK1 PE=3 SV=3
Length=535
Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 67/210 (32%), Positives = 99/210 (47%), Gaps = 21/210 (10%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---------QEID 949
K+R LG G +G+V L C + + +K + D G + EI
Sbjct 59 KVRKLGSGAYGEV-LLCKEKNGHSEKAIKVIKKSQFDKGRYNDDNKNIEKFHEEIYNEIS 117
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQIC 1008
+L++L H +IIK ED+ K LV E+ G L + RH +QI
Sbjct 118 LLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQIL 175
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
G+ YLH + +HRD+ N+LL+N +KI DFGL+ + Y++R D
Sbjct 176 SGICYLHKHNIVHRDIKPENILLENKNSLLNIKIVDFGLSSFFSKD---YKLR-DRLGTA 231
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
++ APE LK+ K+ DVWS GV +Y LL
Sbjct 232 YYIAPEVLKK-KYNEKCDVWSCGVIMYILL 260
Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 51/227 (22%), Positives = 88/227 (39%), Gaps = 29/227 (13%)
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVWL 699
K ++ H +I Y SL+ + H ++ + V +VTE+ E G L +
Sbjct 103 KNIEKFHEEI----YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIIN 158
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R + A + +Q+ S + YL N+VH ++ NILL E + + +
Sbjct 159 RHKFDECDAA---NIMKQILSGICYLHKHNIVHRDIKPENILL------ENKNSLLNIKI 209
Query 760 PGVGLGALSRE-----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATL-LEIC----F 809
GL + + +R+ ++APE L N D W G + + +C F
Sbjct 210 VDFGLSSFFSKDYKLRDRLGTAYYIAPEVLKKKYNE---KCDVWSCGVIMYILLCGYPPF 266
Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
G+ EK +Y + S + L LTY+ +R
Sbjct 267 GGQNDQDIIKKVEKGKYYFDFNDWKNIS-DEAKELIKLMLTYDYNKR 312
>sp|C0LGU1|Y5374_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At5g37450 OS=Arabidopsis thaliana OX=3702
GN=At5g37450 PE=1 SV=1
Length=959
Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 68/209 (33%), Positives = 107/209 (51%), Gaps = 23/209 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEH 958
+ +G G +GKV Y G G +VAVK +A+ G Q + + EI++L L+H +
Sbjct 634 LSQIGRGGYGKV----YKGHLPG-GLVVAVK--RAEQGSLQGQKEFFTEIELLSRLHHRN 686
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH 1015
++ G C+ +GE+ LV EY+P GSL+D L R + LA L A G+ YLH
Sbjct 687 LVSLLGYCDQKGEQ--MLVYEYMPNGSLQDALSARFRQPLSLALRLRIALGSARGILYLH 744
Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----W 1067
+ IHRD+ N+LLD+ K+ DFG++K + + V+ D + + +
Sbjct 745 TEADPPIIHRDIKPSNILLDSKMNPKVADFGISKLI--ALDGGGVQRDHVTTIVKGTPGY 802
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096
PE ++ SDV+S G+ E+LT
Sbjct 803 VDPEYYLSHRLTEKSDVYSLGIVFLEILT 831
Score = 38.1 bits (87), Expect = 0.55, Method: Compositional matrix adjust.
Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 4/92 (4%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMV 713
F+ L+S++ H +L + G C + E ++V EY+ +G L D R R + +A ++
Sbjct 672 FFTEIELLSRLHHRNLVSLLGYCDQKGEQMLVYEYMPNGSLQDALSARFRQPLSLALRLR 731
Query 714 VAQQLASALSYLENKN---LVHGNVCGRNILL 742
+A A + YL + ++H ++ NILL
Sbjct 732 IALGSARGILYLHTEADPPIIHRDIKPSNILL 763
>sp|Q08E52|PAK1_BOVIN Serine/threonine-protein kinase PAK 1 OS=Bos
taurus OX=9913 GN=PAK1 PE=1 SV=1
Length=544
Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 63/237 (27%), Positives = 105/237 (44%), Gaps = 28/237 (12%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDL----------------GEGHFGKVSLYCYDPT 919
D LT N + P + + L+K+R + G+G G V Y
Sbjct 232 DALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV----YTAM 287
Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979
+ TG+ VA+K + P+ + EI ++R + +I+ Y E L +VME
Sbjct 288 DVATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVME 344
Query 980 YVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
Y+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+LL D VK+
Sbjct 345 YLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKL 404
Query 1040 GDFGL-AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
DFG A+ PE + R +W APE + + D+WS G+ E++
Sbjct 405 TDFGFCAQITPEQSK----RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI 457
Score = 34.3 bits (77), Expect = 9.5, Method: Compositional matrix adjust.
Identities = 40/150 (27%), Positives = 64/150 (43%), Gaps = 26/150 (17%)
Query 680 GPENIMVTEYVEHGPL-DVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736
G E +V EY+ G L DV + G + V ++ AL +L + ++H ++
Sbjct 336 GDELWVVMEYLAGGSLTDVVTETCMDEGQI-----AAVCRECLQALEFLHSNQVIHRDIK 390
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANS 790
NILL G +KL+D G A E+ +R W+APE + A
Sbjct 391 SDNILLGMDG-------SVKLTD--FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-- 439
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+D W G +E+ +GE P + +P
Sbjct 440 YGPKVDIWSLGIMAIEM-IEGEPPYLNENP 468
>sp|Q9SXB8|Y1133_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g11330 OS=Arabidopsis thaliana OX=3702
GN=At1g11330 PE=1 SV=3
Length=842
Score = 84.7 bits (208), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 88/289 (30%), Positives = 124/289 (43%), Gaps = 41/289 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG P G G+ +AVK L G Q E+ ++ L H ++
Sbjct 530 LGQGGFG--------PVYKGKLPEGQEIAVKRLSRKSG-QGLEELMNEVVVISKLQHRNL 580
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015
+K GCC + E+ LV EY+P SL YL + + + IC G+ YLH
Sbjct 581 VKLLGCCIEGEER--MLVYEYMPKKSLDAYLFDPMKQKILDWKTRFNIMEGICRGLLYLH 638
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
IHRDL A N+LLD + KI DFGLA+ + R + + +PE
Sbjct 639 RDSRLKIIHRDLKASNILLDENLNPKISDFGLARIFRANEDEANTRRVVGTYGY-MSPEY 697
Query 1073 LKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
E F SDV+S GV E+++ +SS L L+ A +L G
Sbjct 698 AMEGFFSEKSDVFSLGVIFLEIISGRRNSSSHKEENNLNLLAYAW---------KLWNDG 748
Query 1132 E--RLPRP---DKC----PCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
E L P DKC + H+ C + A+ RP N+I +L T
Sbjct 749 EAASLADPAVFDKCFEKEIEKCVHIGLLCVQEVANDRPNVSNVIWMLTT 797
Score = 41.6 bits (96), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 57/226 (25%), Positives = 89/226 (39%), Gaps = 45/226 (20%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
+ LGQG VY+G+L PE GQE+ V K L
Sbjct 528 NKLGQGGFGPVYKGKL-------PE----------------GQEIAV--KRLSRKSGQGL 562
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK- 711
++S++ H +L + G C+ G E ++V EY+ LD +L + WK
Sbjct 563 EELMNEVVVISKLQHRNLVKLLGCCIEGEERMLVYEYMPKKSLDAYLFDPMKQKILDWKT 622
Query 712 -MVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LG 765
+ + + L YL + ++H ++ NIL L E +P K+SD G+
Sbjct 623 RFNIMEGICRGLLYLHRDSRLKIIHRDLKASNIL-----LDENLNP--KISDFGLARIFR 675
Query 766 ALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
A E R+ +++PE G S D + G LEI
Sbjct 676 ANEDEANTRRVVGTYGYMSPEYAMEGF--FSEKSDVFSLGVIFLEI 719
>sp|Q9LK35|THE1_ARATH Receptor-like protein kinase THESEUS 1 OS=Arabidopsis
thaliana OX=3702 GN=THE1 PE=1 SV=1
Length=855
Score = 84.7 bits (208), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 69/203 (34%), Positives = 99/203 (49%), Gaps = 23/203 (11%)
Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHEH 958
LG G FG+V Y T DGT VAVK P+ G ++ EI++L L H H
Sbjct 516 LGVGGFGRV----YKGTLEDGTK--VAVKR----GNPRSEQGMAEFRTEIEMLSKLRHRH 565
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI---GLAQLLLFAQQICEGMAYLH 1015
++ G C+++ E + LV EY+ G LR +L + Q L G+ YLH
Sbjct 566 LVSLIGYCDERSE--MILVYEYMANGPLRSHLYGADLPPLSWKQRLEICIGAARGLHYLH 623
Query 1016 ---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+Q IHRD+ N+LLD + + K+ DFGL+K P + + V + PE
Sbjct 624 TGASQSIIHRDVKTTNILLDENLVAKVADFGLSKTGPSLDQTH-VSTAVKGSFGYLDPEY 682
Query 1073 LKEYKFYYASDVWSFGVTLYELL 1095
+ + SDV+SFGV L E+L
Sbjct 683 FRRQQLTEKSDVYSFGVVLMEVL 705
Score = 44.3 bits (103), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 61/258 (24%), Positives = 102/258 (40%), Gaps = 40/258 (16%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K +P F ++S++ H HL + G C E I+V EY+ +GPL
Sbjct 534 KVAVKRGNPRSEQGMAEFRTEIEMLSKLRHRHLVSLIGYCDERSEMILVYEYMANGPL-- 591
Query 698 WLRRERGHV------PMAWK--MVVAQQLASALSYL---ENKNLVHGNVCGRNILLARLG 746
R H+ P++WK + + A L YL +++++H +V NILL
Sbjct 592 -----RSHLYGADLPPLSWKQRLEICIGAARGLHYLHTGASQSIIHRDVKTTNILLDE-N 645
Query 747 LAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
L + F LS G L V+ +L PE L+ D + FG L+
Sbjct 646 LVAKVADF-GLSKTGPSLDQTHVSTAVKGSFGYLDPEYFR--RQQLTEKSDVYSFGVVLM 702
Query 806 EI-----CFDGEAPLQSRSPSEKEHFYQRQHRLPE------------PSCPQLATLTSQC 848
E+ + P + + +E +Q++ L + S + +C
Sbjct 703 EVLCCRPALNPVLPREQVNIAEWAMAWQKKGLLDQIMDSNLTGKVNPASLKKFGETAEKC 762
Query 849 LTYEPTQRPSFRTILRDL 866
L RPS +L +L
Sbjct 763 LAEYGVDRPSMGDVLWNL 780
>sp|G5EGT9|RYK_CAEEL Inactive tyrosine-protein kinase RYK OS=Caenorhabditis
elegans OX=6239 GN=lin-18 PE=1 SV=1
Length=583
Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 49/171 (29%), Positives = 92/171 (54%), Gaps = 18/171 (11%)
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD--NDRL-VKIGDFGLAKAVPEGHEYY 1055
QL+ A Q+ +A++H +H D+AARN L+ N RL V++ D L++ + +Y+
Sbjct 414 QLVSLATQVSSAVAHIHKYRIVHNDIAARNCLIAEVNGRLQVQLCDSALSRDLFPA-DYH 472
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
+ ++ + P+ W +PE + + A+DVWS GV L+EL++ L G
Sbjct 473 CLGDNENRPLKWMSPEAIANELYSSAADVWSLGVLLWELMS--------------LGGSP 518
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
++ + ++ +G+RL +P+ CP ++Y +M CW + RP+ E ++
Sbjct 519 HAEIDPEEVYTMILKGKRLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQVV 569
Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 47/164 (29%), Positives = 72/164 (44%), Gaps = 15/164 (9%)
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLA----RLGLAEGTSPFIKLSDPGVGLGALSR 769
+A Q++SA++++ +VH ++ RN L+A RL + S + P
Sbjct 418 LATQVSSAVAHIHKYRIVHNDIAARNCLIAEVNGRLQVQLCDSALSRDLFPADYHCLGDN 477
Query 770 EERVERIPWLAPECLPGGANSL-STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
E R + W++PE + AN L S+A D W G L E+ G +P P E
Sbjct 478 ENR--PLKWMSPEAI---ANELYSSAADVWSLGVLLWELMSLGGSPHAEIDPEEVYTMIL 532
Query 829 RQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTI---LRDLT 867
+ RL +P +CP QL + C RPS + LRD
Sbjct 533 KGKRLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQVVHGLRDFN 576
>sp|P0CY24|STE20_CANAL Serine/threonine-protein kinase CST20 OS=Candida
albicans (strain SC5314 / ATCC MYA-2876) OX=237561
GN=CST20 PE=3 SV=1
Length=1228
Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 56/195 (29%), Positives = 103/195 (53%), Gaps = 13/195 (7%)
Query 903 LGEGHFGKVSLY--CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G+G G V L D +N +VA+K + + P+ + EI +++ H +I+
Sbjct 957 IGQGASGGVFLAHDVRDKSN-----IVAIKQMNLEQQPK-KELIINEILVMKGSSHPNIV 1010
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ +G+ L ++MEY+ GSL D + + Q+ + ++ +G+ +LH++ I
Sbjct 1011 NFIDSYLLKGD--LWVIMEYMEGGSLTDIVTHSVMTEGQIGVVCRETLKGLKFLHSKGVI 1068
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ + N+LL+ D +KI DFG + E + R+ G +P +W APE + ++
Sbjct 1069 HRDIKSDNILLNMDGNIKITDFGFCAQINEINS-KRITMVG-TP-YWMAPEIVSRKEYGP 1125
Query 1081 ASDVWSFGVTLYELL 1095
DVWS G+ + E+L
Sbjct 1126 KVDVWSLGIMIIEML 1140
Score = 38.9 bits (89), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 43/169 (25%), Positives = 74/169 (44%), Gaps = 26/169 (15%)
Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM--VVAQQ 717
+M SH ++ F+ ++G + ++ EY+E G L + H M VV ++
Sbjct 1000 VMKGSSHPNIVNFIDSYLLKG-DLWVIMEYMEGGSLTDIVT----HSVMTEGQIGVVCRE 1054
Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP 777
L +L +K ++H ++ NILL G IK++D G A E +RI
Sbjct 1055 TLKGLKFLHSKGVIHRDIKSDNILLNMDG-------NIKITD--FGFCAQINEINSKRIT 1105
Query 778 ------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
W+APE + +D W G ++E+ +GE P + +P
Sbjct 1106 MVGTPYWMAPEIV--SRKEYGPKVDVWSLGIMIIEM-LEGEPPYLNETP 1151
>sp|Q66GN2|LRK64_ARATH Lectin-domain containing receptor kinase
VI.4 OS=Arabidopsis thaliana OX=3702 GN=LECRK64 PE=2 SV=1
Length=691
Score = 84.7 bits (208), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 66/209 (32%), Positives = 104/209 (50%), Gaps = 18/209 (9%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
K+ R +G G FG V Y + + +AVK + + R + EI+ L L H
Sbjct 363 FKENRVVGTGGFGIV----YRGNIRSSSDQIAVKKITPNSMQGVRE-FVAEIESLGRLRH 417
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHS---IGLAQLLLFAQQICEG 1010
++++ +G C+ + + L L+ +Y+P GSL L PR S + A+ I G
Sbjct 418 KNLVNLQGWCKHRND--LLLIYDYIPNGSLDSLLYSKPRRSGAVLSWNARFQIAKGIASG 475
Query 1011 MAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH Q IHRD+ NVL+D+D ++GDFGLA+ G + G + +
Sbjct 476 LLYLHEEWEQIVIHRDVKPSNVLIDSDMNPRLGDFGLARLYERGSQSCTTVVVG--TIGY 533
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096
APE + ASDV++FGV L E+++
Sbjct 534 MAPELARNGNSSSASDVFAFGVLLLEIVS 562
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 58/267 (22%), Positives = 110/267 (41%), Gaps = 40/267 (15%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G R ++ +K + P+ F + ++ H +L + G C + +++ +Y
Sbjct 380 GNIRSSSDQIAVKKITPNSMQGVREFVAEIESLGRLRHKNLVNLQGWCKHRNDLLLIYDY 439
Query 690 VEHGPLD--VWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILL 742
+ +G LD ++ + R ++W + +A+ +AS L YL + ++H +V N+L+
Sbjct 440 IPNGSLDSLLYSKPRRSGAVLSWNARFQIAKGIASGLLYLHEEWEQIVIHRDVKPSNVLI 499
Query 743 -ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
+ + G +L + G V I ++APE G + S+A D + FG
Sbjct 500 DSDMNPRLGDFGLARLYERG---SQSCTTVVVGTIGYMAPELARNGNS--SSASDVFAFG 554
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY--------QRQHRLPEPSCPQLATLTSQ------ 847
LLEI + R P++ F+ Q + P+L + +
Sbjct 555 VLLLEI-------VSGRKPTDSGTFFIADWVMELQASGEILSAIDPRLGSGYDEGEARLA 607
Query 848 ------CLTYEPTQRPSFRTILRDLTR 868
C ++P RP R +LR L R
Sbjct 608 LAVGLLCCHHKPESRPLMRMVLRYLNR 634
>sp|O88643|PAK1_MOUSE Serine/threonine-protein kinase PAK 1 OS=Mus
musculus OX=10090 GN=Pak1 PE=1 SV=1
Length=545
Score = 84.0 bits (206), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 63/237 (27%), Positives = 105/237 (44%), Gaps = 28/237 (12%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDL----------------GEGHFGKVSLYCYDPT 919
D LT N + P + + L+K+R + G+G G V Y
Sbjct 233 DALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTPFEKIGQGASGTV----YTAM 288
Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979
+ TG+ VA+K + P+ + EI ++R + +I+ Y E L +VME
Sbjct 289 DVATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVME 345
Query 980 YVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
Y+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+LL D VK+
Sbjct 346 YLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKL 405
Query 1040 GDFGL-AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
DFG A+ PE + R +W APE + + D+WS G+ E++
Sbjct 406 TDFGFCAQITPEQSK----RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI 458
Score = 34.3 bits (77), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 40/150 (27%), Positives = 64/150 (43%), Gaps = 26/150 (17%)
Query 680 GPENIMVTEYVEHGPL-DVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736
G E +V EY+ G L DV + G + V ++ AL +L + ++H ++
Sbjct 337 GDELWVVMEYLAGGSLTDVVTETCMDEGQI-----AAVCRECLQALEFLHSNQVIHRDIK 391
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANS 790
NILL G +KL+D G A E+ +R W+APE + A
Sbjct 392 SDNILLGMDG-------SVKLTD--FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-- 440
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+D W G +E+ +GE P + +P
Sbjct 441 YGPKVDIWSLGIMAIEM-IEGEPPYLNENP 469
>sp|Q39030|KPK2_ARATH Serine/threonine-protein kinase AtPK2/AtPK19
OS=Arabidopsis thaliana OX=3702 GN=ATPK2 PE=1 SV=2
Length=471
Score = 83.6 bits (205), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 80/279 (29%), Positives = 120/279 (43%), Gaps = 23/279 (8%)
Query 827 YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD--- 883
Y R H L PS +L LT T+ L + + D + N D
Sbjct 68 YSRSHSLVGPSLVVSHSLKMNKLTLRETED---SVDLVECVEGESIKENDEFSGNDDTDS 124
Query 884 --SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQ 939
SP V + ++ +G+G FGKV Y T E+ A+K ++ D
Sbjct 125 EKSPEEVSGVVGIEDFEVLKVVGQGAFGKV----YQVRKKDTSEIYAMKVMRKDKIVEKN 180
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ 999
H K E DIL + H I++ K Q + L LV++++ G L L +
Sbjct 181 HAEYMKAERDILTKIDHPFIVQLKYSF--QTKYRLYLVLDFINGGHLFFQLYHQGLFRED 238
Query 1000 LL-LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
L ++ +I +++LH + +HRDL N+L+D D V + DFGLAK E R
Sbjct 239 LARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDVDGHVMLTDFGLAKEFEEN-----TR 293
Query 1059 EDGDSPVFWY-APECLKEYKFYYASDVWSFGVTLYELLT 1096
+ Y APE ++ A+D WS G+ LYE+LT
Sbjct 294 SNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLT 332
Score = 34.3 bits (77), Expect = 9.0, Method: Compositional matrix adjust.
Identities = 36/150 (24%), Positives = 62/150 (41%), Gaps = 19/150 (13%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
V ++ SA+S+L K ++H ++ NIL+ G + L+D G+ A EE
Sbjct 242 VYTAEIVSAVSHLHEKGIMHRDLKPENILMDVDG-------HVMLTDFGL---AKEFEEN 291
Query 773 VER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
++APE + G + A D W G L E+ G+ P ++
Sbjct 292 TRSNSMCGTTEYMAPEIVRGKGH--DKAADWWSVGILLYEM-LTGKPPFLGSKGKIQQKI 348
Query 827 YQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
+ + +LP+ + L L EP +R
Sbjct 349 VKDKIKLPQFLSNEAHALLKGLLQKEPERR 378
>sp|Q13153|PAK1_HUMAN Serine/threonine-protein kinase PAK 1 OS=Homo
sapiens OX=9606 GN=PAK1 PE=1 SV=2
Length=545
Score = 84.0 bits (206), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 63/237 (27%), Positives = 105/237 (44%), Gaps = 28/237 (12%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDL----------------GEGHFGKVSLYCYDPT 919
D LT N + P + + L+K+R + G+G G V Y
Sbjct 233 DALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV----YTAM 288
Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979
+ TG+ VA+K + P+ + EI ++R + +I+ Y E L +VME
Sbjct 289 DVATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVME 345
Query 980 YVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
Y+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+LL D VK+
Sbjct 346 YLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKL 405
Query 1040 GDFGL-AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
DFG A+ PE + R +W APE + + D+WS G+ E++
Sbjct 406 TDFGFCAQITPEQSK----RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI 458
Score = 33.9 bits (76), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 40/150 (27%), Positives = 64/150 (43%), Gaps = 26/150 (17%)
Query 680 GPENIMVTEYVEHGPL-DVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736
G E +V EY+ G L DV + G + V ++ AL +L + ++H ++
Sbjct 337 GDELWVVMEYLAGGSLTDVVTETCMDEGQI-----AAVCRECLQALEFLHSNQVIHRDIK 391
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANS 790
NILL G +KL+D G A E+ +R W+APE + A
Sbjct 392 SDNILLGMDG-------SVKLTD--FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-- 440
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+D W G +E+ +GE P + +P
Sbjct 441 YGPKVDIWSLGIMAIEM-IEGEPPYLNENP 469
>sp|C4YRB7|STE20_CANAW Serine/threonine-protein kinase CST20 OS=Candida
albicans (strain WO-1) OX=294748 GN=CST20 PE=3 SV=2
Length=1224
Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 56/195 (29%), Positives = 103/195 (53%), Gaps = 13/195 (7%)
Query 903 LGEGHFGKVSLY--CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G+G G V L D +N +VA+K + + P+ + EI +++ H +I+
Sbjct 953 IGQGASGGVFLAHDVRDKSN-----IVAIKQMNLEQQPK-KELIINEILVMKGSSHPNIV 1006
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ +G+ L ++MEY+ GSL D + + Q+ + ++ +G+ +LH++ I
Sbjct 1007 NFIDSYLLKGD--LWVIMEYMEGGSLTDIVTHSVMTEGQIGVVCRETLKGLKFLHSKGVI 1064
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ + N+LL+ D +KI DFG + E + R+ G +P +W APE + ++
Sbjct 1065 HRDIKSDNILLNMDGNIKITDFGFCAQINEINS-KRITMVG-TP-YWMAPEIVSRKEYGP 1121
Query 1081 ASDVWSFGVTLYELL 1095
DVWS G+ + E+L
Sbjct 1122 KVDVWSLGIMIIEML 1136
Score = 38.9 bits (89), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 43/169 (25%), Positives = 74/169 (44%), Gaps = 26/169 (15%)
Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM--VVAQQ 717
+M SH ++ F+ ++G + ++ EY+E G L + H M VV ++
Sbjct 996 VMKGSSHPNIVNFIDSYLLKG-DLWVIMEYMEGGSLTDIVT----HSVMTEGQIGVVCRE 1050
Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP 777
L +L +K ++H ++ NILL G IK++D G A E +RI
Sbjct 1051 TLKGLKFLHSKGVIHRDIKSDNILLNMDG-------NIKITD--FGFCAQINEINSKRIT 1101
Query 778 ------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
W+APE + +D W G ++E+ +GE P + +P
Sbjct 1102 MVGTPYWMAPEIV--SRKEYGPKVDVWSLGIMIIEM-LEGEPPYLNETP 1147
>sp|Q9LVP0|Y5639_ARATH Probable leucine-rich repeat receptor-like
protein kinase At5g63930 OS=Arabidopsis thaliana OX=3702
GN=At5g63930 PE=1 SV=1
Length=1102
Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 61/182 (34%), Positives = 90/182 (49%), Gaps = 13/182 (7%)
Query 924 GEMVAVKALKAD--CGPQHR--SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979
G +AVK L ++ G + + ++ EI L + H +I+K G C QG L+ E
Sbjct 826 GYTLAVKKLASNHEGGNNNNVDNSFRAEILTLGNIRHRNIVKLHGFCNHQGSN--LLLYE 883
Query 980 YVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDND 1034
Y+P GSL + L P ++ ++ A +G+AYLH HRD+ + N+LLD+
Sbjct 884 YMPKGSLGEILHDPSCNLDWSKRFKIALGAAQGLAYLHHDCKPRIFHRDIKSNNILLDDK 943
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
+GDFGLAK + H G + APE K SD++S+GV L EL
Sbjct 944 FEAHVGDFGLAKVIDMPHSKSMSAIAGSYG--YIAPEYAYTMKVTEKSDIYSYGVVLLEL 1001
Query 1095 LT 1096
LT
Sbjct 1002 LT 1003
>sp|Q9URY1|PPK16_SCHPO Serine/threonine-protein kinase ppk16 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=ppk16 PE=1 SV=1
Length=672
Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 64/196 (33%), Positives = 91/196 (46%), Gaps = 16/196 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK- 961
+GEG FGKV L + TN LK+ C Q +EI R L H +I +
Sbjct 37 VGEGSFGKVYLAAHLLTNTKV-------VLKSSCRKQ-AIILAREIHHHRRLLHPNITRL 88
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020
Y+ C E + L MEY P G L D++ R + Q+C + YLH Q +
Sbjct 89 YEVVC---TEDRIYLAMEYCPNGELYDWVAREKRLDEKTTCRIMWQLCCAIQYLHRQGCV 145
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
HRDL N+ LD VK+GDFG ++ + G V + APE ++ +K+
Sbjct 146 HRDLKLENIFLDKAYNVKLGDFGFSRDSDCSRRTFMNTRCGT--VAYCAPELVQGHKYIG 203
Query 1080 YASDVWSFGVTLYELL 1095
D+WS G+ +Y LL
Sbjct 204 ECVDIWSLGIIMYALL 219
>sp|Q54Y90|Y0133_DICDI Probable serine/threonine-protein kinase
DDB_G0278665 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0278665
PE=3 SV=1
Length=1090
Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 64/232 (28%), Positives = 109/232 (47%), Gaps = 28/232 (12%)
Query 942 SGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLA 998
S +++E+++ + L +H +I+ + G C LV+EY+ GSL YL P ++
Sbjct 228 SEFEKELEMHKELLHHPNIVHFVGFCVSPK----CLVLEYIEGGSLDKYLHNPNYTFSPQ 283
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL-----DNDRLVKIGDFGLAKAVPEGHE 1053
L A I +GM +LH +H DL +N L+ + +K+ DFGLA +
Sbjct 284 LRLKMANDIAKGMCFLHRNEILHLDLKPQNFLVVSISPEAPVSIKLADFGLATS--SSRS 341
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
+Y +G + +PE + KF A+DVWS+G L E+LT+ Q
Sbjct 342 FYGPTVEGS--FLYMSPEVFTQKKFSRAADVWSYGACLIEILTNKRPYQE---------- 389
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
Q+ L L + E G P + ++ +++ C+ + + RP FEN+
Sbjct 390 --YDQLGYLELARVREEGLPPMIPPEIEGDLRKIIEACFHRDHTKRPNFENI 439
Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 51/204 (25%), Positives = 85/204 (42%), Gaps = 15/204 (7%)
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726
H ++ G CV +V EY+E G LD +L ++ +A +A + +L
Sbjct 243 HPNIVHFVGFCVS--PKCLVLEYIEGGSLDKYLHNPNYTFSPQLRLKMANDIAKGMCFLH 300
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVE-RIPWLAPE 782
++H ++ +N L+ + S IKL+D G+ + SR VE +++PE
Sbjct 301 RNEILHLDLKPQNFLVVSISPEAPVS--IKLADFGLATSS-SRSFYGPTVEGSFLYMSPE 357
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ-- 840
S A D W +GA L+EI + + E R+ LP P+
Sbjct 358 VF--TQKKFSRAADVWSYGACLIEILTNKRPYQEYDQLGYLELARVREEGLPPMIPPEIE 415
Query 841 --LATLTSQCLTYEPTQRPSFRTI 862
L + C + T+RP+F I
Sbjct 416 GDLRKIIEACFHRDHTKRPNFENI 439
>sp|P0CY23|STE20_CANAX Serine/threonine-protein kinase CST20 OS=Candida
albicans OX=5476 GN=CST20 PE=3 SV=1
Length=1230
Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 56/195 (29%), Positives = 103/195 (53%), Gaps = 13/195 (7%)
Query 903 LGEGHFGKVSLY--CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G+G G V L D +N +VA+K + + P+ + EI +++ H +I+
Sbjct 959 IGQGASGGVFLAHDVRDKSN-----IVAIKQMNLEQQPK-KELIINEILVMKGSSHPNIV 1012
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ +G+ L ++MEY+ GSL D + + Q+ + ++ +G+ +LH++ I
Sbjct 1013 NFIDSYLLKGD--LWVIMEYMEGGSLTDIVTHSVMTEGQIGVVCRETLKGLKFLHSKGVI 1070
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ + N+LL+ D +KI DFG + E + R+ G +P +W APE + ++
Sbjct 1071 HRDIKSDNILLNMDGNIKITDFGFCAQINEINS-KRITMVG-TP-YWMAPEIVSRKEYGP 1127
Query 1081 ASDVWSFGVTLYELL 1095
DVWS G+ + E+L
Sbjct 1128 KVDVWSLGIMIIEML 1142
Score = 38.9 bits (89), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 43/169 (25%), Positives = 74/169 (44%), Gaps = 26/169 (15%)
Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM--VVAQQ 717
+M SH ++ F+ ++G + ++ EY+E G L + H M VV ++
Sbjct 1002 VMKGSSHPNIVNFIDSYLLKG-DLWVIMEYMEGGSLTDIVT----HSVMTEGQIGVVCRE 1056
Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP 777
L +L +K ++H ++ NILL G IK++D G A E +RI
Sbjct 1057 TLKGLKFLHSKGVIHRDIKSDNILLNMDG-------NIKITD--FGFCAQINEINSKRIT 1107
Query 778 ------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
W+APE + +D W G ++E+ +GE P + +P
Sbjct 1108 MVGTPYWMAPEIV--SRKEYGPKVDVWSLGIMIIEM-LEGEPPYLNETP 1153
>sp|P35465|PAK1_RAT Serine/threonine-protein kinase PAK 1 OS=Rattus
norvegicus OX=10116 GN=Pak1 PE=1 SV=3
Length=544
Score = 84.0 bits (206), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 63/237 (27%), Positives = 105/237 (44%), Gaps = 28/237 (12%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDL----------------GEGHFGKVSLYCYDPT 919
D LT N + P + + L+K+R + G+G G V Y
Sbjct 232 DALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV----YTAM 287
Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979
+ TG+ VA+K + P+ + EI ++R + +I+ Y E L +VME
Sbjct 288 DVATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVME 344
Query 980 YVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
Y+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+LL D VK+
Sbjct 345 YLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKL 404
Query 1040 GDFGL-AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
DFG A+ PE + R +W APE + + D+WS G+ E++
Sbjct 405 TDFGFCAQITPEQSK----RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI 457
Score = 33.9 bits (76), Expect = 9.9, Method: Compositional matrix adjust.
Identities = 40/150 (27%), Positives = 64/150 (43%), Gaps = 26/150 (17%)
Query 680 GPENIMVTEYVEHGPL-DVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736
G E +V EY+ G L DV + G + V ++ AL +L + ++H ++
Sbjct 336 GDELWVVMEYLAGGSLTDVVTETCMDEGQI-----AAVCRECLQALEFLHSNQVIHRDIK 390
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANS 790
NILL G +KL+D G A E+ +R W+APE + A
Sbjct 391 SDNILLGMDG-------SVKLTD--FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-- 439
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+D W G +E+ +GE P + +P
Sbjct 440 YGPKVDIWSLGIMAIEM-IEGEPPYLNENP 468
>sp|Q6C7U8|PHO85_YARLI Negative regulator of the PHO system OS=Yarrowia
lipolytica (strain CLIB 122 / E 150) OX=284591 GN=PHO85
PE=3 SV=1
Length=294
Score = 81.3 bits (199), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 58/206 (28%), Positives = 98/206 (48%), Gaps = 17/206 (8%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+++ LGEG + V Y N TG++VA+K + D S +EI +++ L H
Sbjct 7 FQQLEKLGEGTYATV----YKGRNRTTGQLVALKEINLDSEEGTPSTAIREISLMKELKH 62
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----SIGLAQLLLFAQQICEGMA 1012
E+I+ E L LV EY+ L+ ++ + ++ Q+ F Q+ G+
Sbjct 63 ENIVTLYDVI--HTENKLNLVFEYMD-KDLKKFMDTNGNKGALETKQVKWFMYQLLRGIL 119
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APE 1071
+ H +HRDL +N+L++ +K+ DFGLA+A + + WY AP+
Sbjct 120 FCHDNRVLHRDLKPQNLLINAKGQLKLADFGLARAFGIPVNTF----SNEVVTLWYRAPD 175
Query 1072 CLKEYKFYYAS-DVWSFGVTLYELLT 1096
L + Y S D+WS G + E+ T
Sbjct 176 VLLGSRTYSTSIDIWSAGCIMAEMFT 201
>sp|A0A509AHB6|CDPK1_PLABA Calcium-dependent protein kinase 1
OS=Plasmodium berghei (strain Anka) OX=5823 GN=CDPK1 PE=1 SV=1
Length=523
Score = 84.0 bits (206), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 67/210 (32%), Positives = 98/210 (47%), Gaps = 21/210 (10%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---------QEID 949
K+R LG G +G+V L C + + +K + D G EI
Sbjct 59 KVRKLGSGAYGEV-LLCKEKNGHSEKAIKVIKKSQFDKGRYSDDNKNIEKFHEEIYNEIS 117
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQIC 1008
+L++L H +IIK ED+ K LV E+ G L + RH +QI
Sbjct 118 LLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQIL 175
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
G+ YLH + +HRD+ N+LL+N +KI DFGL+ + Y++R D
Sbjct 176 SGICYLHKHNIVHRDIKPENILLENKNSLLNIKIVDFGLSSFFSKD---YKLR-DRLGTA 231
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
++ APE LK+ K+ DVWS GV +Y LL
Sbjct 232 YYIAPEVLKK-KYNEKCDVWSCGVIMYILL 260
Score = 38.5 bits (88), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 52/227 (23%), Positives = 90/227 (40%), Gaps = 29/227 (13%)
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVWL 699
K ++ H +I Y SL+ + H ++ + V +VTE+ E G L +
Sbjct 103 KNIEKFHEEI----YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIIN 158
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R + A + +Q+ S + YL N+VH ++ NILL E + + +
Sbjct 159 RHKFDECDAA---NIMKQILSGICYLHKHNIVHRDIKPENILL------ENKNSLLNIKI 209
Query 760 PGVGLGA-LSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATL-LEIC----F 809
GL + S++ +R+ ++APE L N D W G + + +C F
Sbjct 210 VDFGLSSFFSKDYKLRDRLGTAYYIAPEVLKKKYNE---KCDVWSCGVIMYILLCGYPPF 266
Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
G+ EK +Y + S + L LTY+ +R
Sbjct 267 GGQNDQDIIKKVEKGKYYFDFNDWKNIS-DEAKELIKLMLTYDYNKR 312
>sp|Q13177|PAK2_HUMAN Serine/threonine-protein kinase PAK 2 OS=Homo
sapiens OX=9606 GN=PAK2 PE=1 SV=3
Length=524
Score = 84.0 bits (206), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 60/209 (29%), Positives = 100/209 (48%), Gaps = 16/209 (8%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP + RY K +G+G G V + T+ G+ VA+K + P+ + E
Sbjct 244 DPKKKYTRYEK----IGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINE 294
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +++ L + +I+ + E L +VMEY+ GSL D + + AQ+ ++
Sbjct 295 ILVMKELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCREC 352
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066
+ + +LHA IHRD+ + NVLL + VK+ DFG A+ PE + R +
Sbjct 353 LQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 408
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095
W APE + + D+WS G+ E++
Sbjct 409 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 437
Score = 37.7 bits (86), Expect = 0.78, Method: Compositional matrix adjust.
Identities = 49/215 (23%), Positives = 90/215 (42%), Gaps = 26/215 (12%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719
+M ++ + ++ + G E +V EY+ G L DV +A V ++
Sbjct 297 VMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIA---AVCRECL 353
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777
AL +L ++H ++ N+LL EG+ +KL+D G A E+ +R
Sbjct 354 QALEFLHANQVIHRDIKSDNVLLG----MEGS---VKLTD--FGFCAQITPEQSKRSTMV 404
Query 778 ----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---- 829
W+APE + A +D W G +E+ +GE P + +P +
Sbjct 405 GTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNGTP 461
Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ + PE P ++CL + +R S + +L+
Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496
>sp|P93050|RKF3_ARATH Probable LRR receptor-like serine/threonine-protein
kinase RKF3 OS=Arabidopsis thaliana OX=3702 GN=RKF3
PE=2 SV=1
Length=617
Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 87/298 (29%), Positives = 138/298 (46%), Gaps = 56/298 (19%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G +G V DGT VA K K +C + + E++++ ++ H +++
Sbjct 289 IGRGGYGNV---FKGALPDGT--QVAFKRFK-NCSAGGDANFAHEVEVIASIRHVNLLAL 342
Query 963 KGCCED----QGEKSLQLVMEYVPLGSLRDYL-------------PRHSIGLAQLLLFAQ 1005
+G C +G + + +V + V GSL D+L R ++G+A+
Sbjct 343 RGYCTATTPYEGHQRI-IVCDLVSNGSLHDHLFGDLEAQLAWPLRQRIALGMAR------ 395
Query 1006 QICEGMAYLH--AQ-HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
G+AYLH AQ IHRD+ A N+LLD K+ DFGLAK PEG + R G
Sbjct 396 ----GLAYLHYGAQPSIIHRDIKASNILLDERFEAKVADFGLAKFNPEGMTHMSTRVAGT 451
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQG 1117
+ + APE + SDV+SFGV L ELL+ D P + +A
Sbjct 452 --MGYVAPEYALYGQLTEKSDVYSFGVVLLELLSRRKAIVTDEEGQP-------VSVADW 502
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEV---YHLMKN-CWETEASFRPTFENLIPILKT 1171
+++R + L+ E P+K P EV Y L+ C + RPT + ++ +L++
Sbjct 503 AWSLVREGQTLDVVED-GMPEKGPPEVLEKYVLIAVLCSHPQLHARPTMDQVVKMLES 559
>sp|Q8AXB4|PAK3_XENLA Serine/threonine-protein kinase PAK 3 OS=Xenopus
laevis OX=8355 GN=pak3 PE=2 SV=1
Length=564
Score = 84.0 bits (206), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 71/262 (27%), Positives = 117/262 (45%), Gaps = 25/262 (10%)
Query 836 PSCPQLATLTSQCLT-YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894
P PQ S T Y T R ++ + D L+ L +++V DP +
Sbjct 238 PVTPQPENSNSSTSTLYRNTDRQRKKSKMTDEEILE--KLRSIVSV------GDPKKKYT 289
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R+ K +G+G G V Y + TG+ VA+K + P+ + EI ++R
Sbjct 290 RFEK----IGQGASGTV----YTAIDIATGQEVAIKQMNLQQQPK-KELIINEILVMREN 340
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYL 1014
+ +I+ Y E L +VMEY+ GSL D + + Q+ ++ + + +L
Sbjct 341 KNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFL 398
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
H+ IHRD+ + N+LL D VK+ DFG A+ PE + R +W APE +
Sbjct 399 HSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK----RSTMVGTPYWMAPEVV 454
Query 1074 KEYKFYYASDVWSFGVTLYELL 1095
+ D+WS G+ E++
Sbjct 455 TRKAYGPKVDIWSLGIMAIEMV 476
Score = 34.3 bits (77), Expect = 9.3, Method: Compositional matrix adjust.
Identities = 40/150 (27%), Positives = 64/150 (43%), Gaps = 26/150 (17%)
Query 680 GPENIMVTEYVEHGPL-DVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736
G E +V EY+ G L DV + G + V ++ AL +L + ++H ++
Sbjct 355 GDELWVVMEYLAGGSLTDVVTETCMDEGQI-----AAVCRECLQALDFLHSNQVIHRDIK 409
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANS 790
NILL G +KL+D G A E+ +R W+APE + A
Sbjct 410 SDNILL-------GMDGSVKLTD--FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-- 458
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+D W G +E+ +GE P + +P
Sbjct 459 YGPKVDIWSLGIMAIEMV-EGEPPYLNENP 487
>sp|P51839|GUC2D_RAT Guanylate cyclase 2D OS=Rattus norvegicus
OX=10116 GN=Gucy2d PE=1 SV=2
Length=1110
Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 76/272 (28%), Positives = 122/272 (45%), Gaps = 31/272 (11%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
GE V +K +A P R + +R + HE++ + G G + +V+E+
Sbjct 577 GEWVWLKKFEAGTAPDLRPSSLSLLRKMREMRHENVTAFLGLF--VGPEVSAMVLEHCAR 634
Query 984 GSLRDYLPRHSIGL-----AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
GSL D L + L A LLL + G+ YLH +H+ H L +RN ++D ++K
Sbjct 635 GSLEDLLRNEDLRLDWTFKASLLL---DLIRGLRYLHHRHFPHGRLKSRNCVVDTRFVLK 691
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK-------EYKFYYASDVWSFGVTL 1091
I D G A+ + E H +R + + W APE L+ K + DV+S G+ L
Sbjct 692 ITDHGYAEFL-ESHCSFR-PQPAPEELLWTAPELLRGPRRPWGPGKATFKGDVFSLGIIL 749
Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
E+LT + PP L + + ++ L PD+ P E LM+ C
Sbjct 750 QEVLT-----RDPPYCSWGL----SAEEIIRKVASPPPLCRPLVSPDQGPLECIQLMQLC 800
Query 1152 WETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183
WE RP+ + + K+++ QG+ SV
Sbjct 801 WEEAPDDRPSLDQIYTQFKSIN---QGKKTSV 829
Score = 40.0 bits (92), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 57/222 (26%), Positives = 86/222 (39%), Gaps = 32/222 (14%)
Query 662 MSQVSHTHLAFVHGVCVRGPE-NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
M ++ H ++ G+ V GPE + MV E+ G L+ LR E + +K + L
Sbjct 604 MREMRHENVTAFLGLFV-GPEVSAMVLEHCARGSLEDLLRNEDLRLDWTFKASLLLDLIR 662
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-----EERVER 775
L YL +++ HG + RN ++ T +K++D G S + E
Sbjct 663 GLRYLHHRHFPHGRLKSRNCVV-------DTRFVLKITDHGYAEFLESHCSFRPQPAPEE 715
Query 776 IPWLAPECL-----PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
+ W APE L P G + D + G L E+ + P S S +E R+
Sbjct 716 LLWTAPELLRGPRRPWGPGKATFKGDVFSLGIILQEV-LTRDPPYCSWGLSAEEII--RK 772
Query 831 HRLPEPSCPQLAT----------LTSQCLTYEPTQRPSFRTI 862
P P C L + L C P RPS I
Sbjct 773 VASPPPLCRPLVSPDQGPLECIQLMQLCWEEAPDDRPSLDQI 814
>sp|Q17850|PK1_CAEEL Serine/threonine-protein kinase pak-1 OS=Caenorhabditis
elegans OX=6239 GN=pak-1 PE=1 SV=2
Length=572
Score = 84.0 bits (206), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 59/205 (29%), Positives = 97/205 (47%), Gaps = 18/205 (9%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R +K+ +G G G V Y T VA+K + P+ + EI ++R
Sbjct 293 RKYRKVDKIGSGASGSV----YTAIEISTEAEVAIKQMNLKDQPK-KELIINEILVMREN 347
Query 955 YHEHIIKYKG---CCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011
H +I+ Y C++ L +VMEY+ GSL D + + + +++ + +
Sbjct 348 KHANIVNYLDSYLVCDE-----LWVVMEYLAGGSLTDVVTECQMEDGIIAAVCREVLQAL 402
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVFWYAP 1070
+LH++H IHRD+ + N+LL D VK+ DFG A+ PE R R +W AP
Sbjct 403 EFLHSRHVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPE----QRKRTTMVGTPYWMAP 458
Query 1071 ECLKEYKFYYASDVWSFGVTLYELL 1095
E + ++ DVWS G+ E++
Sbjct 459 EVVTRKQYGPKVDVWSLGIMAIEMV 483
Score = 37.4 bits (85), Expect = 0.91, Method: Compositional matrix adjust.
Identities = 31/112 (28%), Positives = 53/112 (47%), Gaps = 16/112 (14%)
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER- 772
V +++ AL +L +++++H ++ NILL G +KL+D G LS E+R
Sbjct 394 VCREVLQALEFLHSRHVIHRDIKSDNILL-------GMDGSVKLTDFGF-CAQLSPEQRK 445
Query 773 ----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
V W+APE + +D W G +E+ +GE P + +P
Sbjct 446 RTTMVGTPYWMAPEVV--TRKQYGPKVDVWSLGIMAIEMV-EGEPPYLNENP 494
>sp|C0LGH2|Y1561_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g56130 OS=Arabidopsis thaliana OX=3702
GN=At1g56130 PE=2 SV=2
Length=1032
Score = 84.7 bits (208), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 67/208 (32%), Positives = 99/208 (48%), Gaps = 32/208 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG V N G +VAVK L Q + + EI + ++ H +++K
Sbjct 700 LGEGGFGPVY-----KGNLNDGRVVAVKLLSVGS-RQGKGQFVAEIVAISSVLHRNLVKL 753
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLR-----------DYLPRHSIGLAQLLLFAQQICEGM 1011
GCC +GE + LV EY+P GSL D+ R+ I L + G+
Sbjct 754 YGCCF-EGEHRM-LVYEYLPNGSLDQALFGDKTLHLDWSTRYEICLG--------VARGL 803
Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
YLH + +HRD+ A N+LLD+ + +I DFGLAK + + R G + +
Sbjct 804 VYLHEEASVRIVHRDVKASNILLDSRLVPQISDFGLAKLYDDKKTHISTRVAG--TIGYL 861
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLT 1096
APE +DV++FGV EL++
Sbjct 862 APEYAMRGHLTEKTDVYAFGVVALELVS 889
Score = 43.9 bits (102), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 55/209 (26%), Positives = 88/209 (42%), Gaps = 32/209 (15%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K+L F +S V H +L ++G C G ++V EY+ +G LD
Sbjct 719 VAVKLLSVGSRQGKGQFVAEIVAISSVLHRNLVKLYGCCFEGEHRMLVYEYLPNGSLDQA 778
Query 699 LRRERG-HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILL-ARLGLAEGTSP 753
L ++ H+ + + + +A L YL + +VH +V NILL +RL
Sbjct 779 LFGDKTLHLDWSTRYEICLGVARGLVYLHEEASVRIVHRDVKASNILLDSRL-------- 830
Query 754 FIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
++SD GL L +++ I +LAPE G L+ D + FG LE
Sbjct 831 VPQISD--FGLAKLYDDKKTHISTRVAGTIGYLAPEYAMRG--HLTEKTDVYAFGVVALE 886
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
L S P+ E+ + + L E
Sbjct 887 --------LVSGRPNSDENLEEEKKYLLE 907
>sp|Q5SUV5|MYLK4_MOUSE Myosin light chain kinase family member
4 OS=Mus musculus OX=10090 GN=Mylk4 PE=1 SV=2
Length=386
Score = 82.8 bits (203), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 66/202 (33%), Positives = 103/202 (51%), Gaps = 24/202 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG+V + TG +A K +K G + + K EI ++ L H ++I+
Sbjct 113 LGGGRFGQV----HKCEEKATGLKLAAKIIKTR-GAKDKEDVKNEISVMNQLDHVNLIQL 167
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020
E + + + LVM+ V G L D + + L +L +LF +QICEG+ Y+H + +
Sbjct 168 YDAFESKHD--IILVMD-VEGGELFDRIIDENCNLTELDTILFMKQICEGIRYMHQMYIL 224
Query 1021 HRDLAARNVLLDN--DRLVKIGDFGLAKAVPEGHEYYRVRE----DGDSPVFWYAPECLK 1074
H DL N+L N + +KI DFGLA+ Y+ RE + +P F APE +
Sbjct 225 HLDLKPENILCVNRDAKQIKIIDFGLAR-------RYKPREKLKVNFGTPEF-LAPEVVN 276
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+++D+WS GV Y LL+
Sbjct 277 YDFVSFSTDMWSVGVITYMLLS 298
>sp|Q03147|CDK7_MOUSE Cyclin-dependent kinase 7 OS=Mus musculus
OX=10090 GN=Cdk7 PE=1 SV=2
Length=346
Score = 82.0 bits (201), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 72/234 (31%), Positives = 111/234 (47%), Gaps = 27/234 (12%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ----EID 949
KRY +K+ LGEG F V Y + T ++VA+K +K + + G + EI
Sbjct 10 KRY-EKLDFLGEGQFATV----YKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIK 64
Query 950 ILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQ 1006
+L+ L H +II G + G KS + LV +++ L + +S+ L + + +
Sbjct 65 LLQELSHPNII---GLLDAFGHKSNISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLM 120
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+G+ YLH +HRDL N+LLD + ++K+ DFGLAK+ + Y
Sbjct 121 TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAY----THQVVTR 176
Query 1067 WY-APECLKEYKFY-YASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIG 1113
WY APE L + Y D+W+ G L ELL DS T+ E +G
Sbjct 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLG 230
>sp|C0LGD9|Y1756_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g07560 OS=Arabidopsis thaliana OX=3702
GN=At1g07560 PE=1 SV=1
Length=871
Score = 84.3 bits (207), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 63/201 (31%), Positives = 101/201 (50%), Gaps = 13/201 (6%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LG+G FG V Y +GT E VAVK L ++ +K E+++L +YH +++
Sbjct 574 RVLGKGGFGMV----YHGYINGTEE-VAVKLLSPSSAQGYKE-FKTEVELLLRVYHTNLV 627
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQ-- 1017
G C+++ L L+ +Y+ G L+ + SI L A G+ YLH
Sbjct 628 SLVGYCDEKDH--LALIYQYMVNGDLKKHFSGSSIISWVDRLNIAVDAASGLEYLHIGCK 685
Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRD+ + N+LLD+ K+ DFGL+++ P G E + V + E +
Sbjct 686 PLIVHRDVKSSNILLDDQLQAKLADFGLSRSFPIGDESH-VSTLVAGTFGYLDHEYYQTN 744
Query 1077 KFYYASDVWSFGVTLYELLTH 1097
+ SDV+SFGV L E++T+
Sbjct 745 RLSEKSDVYSFGVVLLEIITN 765
Score = 39.3 bits (90), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 53/189 (28%), Positives = 78/189 (41%), Gaps = 24/189 (13%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G G E V +K+L PS F L+ +V HT+L + G C ++ +Y
Sbjct 587 GYINGTE-EVAVKLLSPSSAQGYKEFKTEVELLLRVYHTNLVSLVGYCDEKDHLALIYQY 645
Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLAR 744
+ +G L + G ++W ++ +A AS L YL +VH +V NILL
Sbjct 646 MVNGDLK---KHFSGSSIISWVDRLNIAVDAASGLEYLHIGCKPLIVHRDVKSSNILLDD 702
Query 745 LGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP-----WLAPECLPGGANSLSTAMDKW 798
A KL+D G+ + E V + +L E N LS D +
Sbjct 703 QLQA-------KLADFGLSRSFPIGDESHVSTLVAGTFGYLDHEYYQ--TNRLSEKSDVY 753
Query 799 GFGATLLEI 807
FG LLEI
Sbjct 754 SFGVVLLEI 762
>sp|P50613|CDK7_HUMAN Cyclin-dependent kinase 7 OS=Homo sapiens
OX=9606 GN=CDK7 PE=1 SV=1
Length=346
Score = 82.0 bits (201), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 72/234 (31%), Positives = 112/234 (48%), Gaps = 27/234 (12%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ----EID 949
KRY +K+ LGEG F V Y + T ++VA+K +K + + G + EI
Sbjct 10 KRY-EKLDFLGEGQFATV----YKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIK 64
Query 950 ILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQ 1006
+L+ L H +II G + G KS + LV +++ L + +S+ L + + +
Sbjct 65 LLQELSHPNII---GLLDAFGHKSNISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLM 120
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+G+ YLH +HRDL N+LLD + ++K+ DFGLAK+ + Y +
Sbjct 121 TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQ----VVTR 176
Query 1067 WY-APECLKEYKFY-YASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIG 1113
WY APE L + Y D+W+ G L ELL DS T+ E +G
Sbjct 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLG 230
>sp|Q9LPZ3|Y1141_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g11410 OS=Arabidopsis thaliana OX=3702
GN=At1g11410 PE=3 SV=3
Length=845
Score = 84.3 bits (207), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 72/205 (35%), Positives = 101/205 (49%), Gaps = 24/205 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDG---TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG G FG P G G +AVK L G Q +K E+ ++ L H ++
Sbjct 529 LGAGGFG--------PVYKGVLQNGMEIAVKRLSKSSG-QGMEEFKNEVKLISKLQHRNL 579
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYL 1014
++ GCC + EK LV EY+P SL DY H A+L + + I G+ YL
Sbjct 580 VRILGCCVEFEEK--MLVYEYLPNKSL-DYFIFHEEQRAELDWPKRMGIIRGIGRGILYL 636
Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
H IHRDL A NVLLDN+ + KI DFGLA+ + G++ + +PE
Sbjct 637 HQDSRLRIIHRDLKASNVLLDNEMIPKIADFGLAR-IFGGNQIEGSTNRVVGTYGYMSPE 695
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
+ +F SDV+SFGV + E++T
Sbjct 696 YAMDGQFSIKSDVYSFGVLILEIIT 720
Score = 46.6 bits (109), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 52/228 (23%), Positives = 96/228 (42%), Gaps = 32/228 (14%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+LS + T ++ +L G G +G + + G E+ V K L S
Sbjct 512 ELSTIATATNNFAFQNKLGAGGFGPVYKGVLQN----------GMEIAV--KRLSKSSGQ 559
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
F L+S++ H +L + G CV E ++V EY+ + LD ++ E + W
Sbjct 560 GMEEFKNEVKLISKLQHRNLVRILGCCVEFEEKMLVYEYLPNKSLDYFIFHEEQRAELDW 619
Query 711 --KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763
+M + + + + YL + ++H ++ N+LL + K++D G+
Sbjct 620 PKRMGIIRGIGRGILYLHQDSRLRIIHRDLKASNVLLDNEMIP-------KIADFGLARI 672
Query 764 LGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
G E R+ +++PE G S+ + D + FG +LEI
Sbjct 673 FGGNQIEGSTNRVVGTYGYMSPEYAMDGQFSIKS--DVYSFGVLILEI 718
>sp|A8X0C4|PAR4_CAEBR Serine/threonine-protein kinase par-4 OS=Caenorhabditis
briggsae OX=6238 GN=par-4 PE=3 SV=2
Length=649
Score = 84.0 bits (206), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 61/205 (30%), Positives = 102/205 (50%), Gaps = 19/205 (9%)
Query 903 LGEGHFGKVS--LYCYDPTNDGTGEMVAVKALKADCGPQHRSGW---KQEIDILRTLYHE 957
+G G +GKV + Y T A K +K + + +GW + E+ ILR L H
Sbjct 203 IGTGSYGKVKEVIDIYTITRR------AAKIMKYEKLRKIPNGWDNIRSEMSILRRLNHR 256
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYL 1014
+I+K + + ++ EY +GS+++ + P H + + + ++C G+ YL
Sbjct 257 NIVKLIEVFNLPEKGKVYMIFEYC-IGSVQNLIDMEPAHRLSIGESHAIFLELCHGLNYL 315
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL- 1073
H++ H+D+ N+LL D VKI DFG+A+ + R + +P F PEC+
Sbjct 316 HSKRVSHKDIKPGNLLLSIDMTVKICDFGVAEQICLFQSDGRCTKVNGTPKFQ-PPECVY 374
Query 1074 --KEYKFYYASDVWSFGVTLYELLT 1096
EY Y D+WS GVTLY +++
Sbjct 375 GNHEYFDGYKVDMWSAGVTLYNMVS 399
>sp|C0LGG8|Y5343_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g53430 OS=Arabidopsis thaliana OX=3702
GN=At1g53430 PE=1 SV=1
Length=1038
Score = 84.7 bits (208), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 73/244 (30%), Positives = 113/244 (46%), Gaps = 38/244 (16%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG V G +AVK L + +R + EI ++ L H +++K
Sbjct 675 IGEGGFGPVYKGVL-----ADGMTIAVKQLSSKSKQGNRE-FVTEIGMISALQHPNLVKL 728
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLR-------------DYLPRHSIGLAQLLLFAQQICE 1009
GCC + K L LV EY+ SL D+ R+ I + I +
Sbjct 729 YGCCIEG--KELLLVYEYLENNSLARALFGTEKQRLHLDWSTRNKICIG--------IAK 778
Query 1010 GMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G+AYLH + +HRD+ A NVLLD KI DFGLAK + + + R G +
Sbjct 779 GLAYLHEESRLKIVHRDIKATNVLLDLSLNAKISDFGLAKLNDDENTHISTRIAG--TIG 836
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIG---IAQGQMTVL 1122
+ APE +DV+SFGV E+++ +++ P +F+ L+ + Q Q ++L
Sbjct 837 YMAPEYAMRGYLTDKADVYSFGVVCLEIVSGKSNTNYRPKEEFVYLLDWAYVLQEQGSLL 896
Query 1123 RLTE 1126
L +
Sbjct 897 ELVD 900
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 68/270 (25%), Positives = 111/270 (41%), Gaps = 48/270 (18%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+ + +K L F ++S + H +L ++G C+ G E ++V EY+E+ L
Sbjct 692 MTIAVKQLSSKSKQGNREFVTEIGMISALQHPNLVKLYGCCIEGKELLLVYEYLENNSLA 751
Query 697 VWL---RRERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEG 750
L ++R H+ + + + +A L+YL ++ +VH ++ N+LL L L
Sbjct 752 RALFGTEKQRLHLDWSTRNKICIGIAKGLAYLHEESRLKIVHRDIKATNVLL-DLSLNAK 810
Query 751 TSPFIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGAT 803
S F GL L+ +E I ++APE G L+ D + FG
Sbjct 811 ISDF--------GLAKLNDDENTHISTRIAGTIGYMAPEYAMRGY--LTDKADVYSFGVV 860
Query 804 LLEICFDGEAPLQSRSPSEK-------EHFYQRQHRLPEPSCPQLATLTSQ--------- 847
LEI G++ R P E+ + Q Q L E P L T S+
Sbjct 861 CLEIV-SGKSNTNYR-PKEEFVYLLDWAYVLQEQGSLLELVDPDLGTSFSKKEAMRMLNI 918
Query 848 ---CLTYEPTQRP---SFRTILRDLTRLQP 871
C PT RP S ++L ++QP
Sbjct 919 ALLCTNPSPTLRPPMSSVVSMLEGKIKVQP 948
>sp|Q9R0G8|NRK_MOUSE Nik-related protein kinase OS=Mus musculus
OX=10090 GN=Nrk PE=1 SV=2
Length=1455
Score = 84.7 bits (208), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 79/301 (26%), Positives = 131/301 (44%), Gaps = 56/301 (19%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-------------QHRSGWK-- 945
+ +G G +G++ L ++ TG +VAVK + A P Q GW+
Sbjct 29 KAIGLGTYGRIFLGIHE----KTGSLVAVKVMSARKTPLPEIGRRVRVNKYQKSVGWRYS 84
Query 946 -------QEIDILRTL-YHEHIIKYKGCCEDQG----EKSLQLVMEYVPLGSLRDYLP-- 991
E+++LR +H++I+ + G + L +VME GS+ D +
Sbjct 85 DEEEDLRTELNLLRKYSFHKNIVTFYGAFFKLNPPGHQHQLWMVMELCAAGSVTDVVRMT 144
Query 992 -RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
S+ + ++I +G+A+LHA IHRD+ +NVLL +D VKI DFG++ V
Sbjct 145 RNQSLKEDWIAYICREILQGLAHLHAHQVIHRDIKGQNVLLTHDAEVKIVDFGVSAQVSR 204
Query 1051 GHEYYRVREDGDSPVFWYAPECLK-----EYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ R +W APE + + Y SDVWS G+T E+ + +PP
Sbjct 205 TNGR---RNSFIGTPYWMAPEVIHCDEDPRCSYDYRSDVWSVGITAIEM-----AEGAPP 256
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L+ + + +LR + R + + M+NC FRPT N+
Sbjct 257 LCKLQPL---EALCVILREAAPKVKSSGWSR------KFQNFMENCMIKNFLFRPTSGNM 307
Query 1166 I 1166
+
Sbjct 308 L 308
Score = 37.0 bits (84), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 46/200 (23%), Positives = 74/200 (37%), Gaps = 29/200 (15%)
Query 632 DRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
D ++LR L +L S H + FY ++ H H + MV E
Sbjct 85 DEEEDLRTELNLLRKYSFHKNIVTFYGAFFKLNPPGHQHQLW------------MVMELC 132
Query 691 EHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
G + +R R + W + +++ L++L ++H ++ G+N+LL
Sbjct 133 AAGSVTDVVRMTRNQSLKEDWIAYICREILQGLAHLHAHQVIHRDIKGQNVLLTH----- 187
Query 750 GTSPFIKLSDPGVGLGALSREERVERIP----WLAPE---CLPGGANSLSTAMDKWGFGA 802
+K+ D GV R W+APE C S D W G
Sbjct 188 --DAEVKIVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIHCDEDPRCSYDYRSDVWSVGI 245
Query 803 TLLEICFDGEAPLQSRSPSE 822
T +E+ +G PL P E
Sbjct 246 TAIEMA-EGAPPLCKLQPLE 264
>sp|Q6I5Q6|RK185_ORYSJ Receptor-like cytoplasmic kinase 185 OS=Oryza
sativa subsp. japonica OX=39947 GN=RLCK185 PE=1 SV=1
Length=491
Score = 83.2 bits (204), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 69/202 (34%), Positives = 102/202 (50%), Gaps = 17/202 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG+V Y N G+ VAVK L + G Q + E+ +L L+H++++
Sbjct 86 LGEGGFGRV--YKGHLEN---GQAVAVKQLDRN-GLQGNREFLVEVLMLSLLHHDNLVNL 139
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
G C D G++ L LV E++PLGSL D+L + + + A +G+ +LH +
Sbjct 140 IGYCAD-GDQRL-LVYEFMPLGSLEDHLHDIPPDKEPLDWNTRMKIAAGAAKGLEFLHDK 197
Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
I+RD + N+LL K+ DFGLAK P G + + V + APE
Sbjct 198 ANPPVIYRDFKSSNILLGEGYHPKLSDFGLAKLGPVGDKTH-VSTRVMGTYGYCAPEYAM 256
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ SDV+SFGV EL+T
Sbjct 257 TGQLTVKSDVYSFGVVFLELIT 278
>sp|A8R7E6|CERK1_ARATH Chitin elicitor receptor kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=CERK1 PE=1 SV=1
Length=617
Score = 84.0 bits (206), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 81/288 (28%), Positives = 130/288 (45%), Gaps = 40/288 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FG V Y + GE A+K + + Q + E+ +L ++H ++++
Sbjct 328 IGQGGFGAV-YYA-----ELRGEKAAIKKMDMEASKQ----FLAELKVLTRVHHVNLVRL 377
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018
G C E SL LV EYV G+L +L R + + + A G+ Y+H
Sbjct 378 IGYCV---EGSLFLVYEYVENGNLGQHLHGSGREPLPWTKRVQIALDSARGLEYIHEHTV 434
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075
Y+HRD+ + N+L+D K+ DFGL K G R G F Y APE +
Sbjct 435 PVYVHRDIKSANILIDQKFRAKVADFGLTKLTEVGGSATR----GAMGTFGYMAPETVYG 490
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV----LRLTELLERG 1131
+ DV++FGV LYEL+ S++ K E +G +G + V + T+ E
Sbjct 491 -EVSAKVDVYAFGVVLYELI----SAKGAVVKMTEAVGEFRGLVGVFEESFKETDKEEAL 545
Query 1132 ERLPRP---DKCPCEVYHLM----KNCWETEASFRPTFENLIPILKTV 1172
++ P D P + + M K C + A RP+ ++ L T+
Sbjct 546 RKIIDPRLGDSYPFDSVYKMAELGKACTQENAQLRPSMRYIVVALSTL 593
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 60/247 (24%), Positives = 101/247 (41%), Gaps = 44/247 (18%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F ++++V H +L + G CV G +V EYVE+G L L G P+ W ++
Sbjct 359 FLAELKVLTRVHHVNLVRLIGYCVEGSL-FLVYEYVENGNLGQHLHGS-GREPLPWTKRV 416
Query 713 VVAQQLASALSYLENKNL---VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LG 765
+A A L Y+ + VH ++ NIL+ + A K++D G+ +G
Sbjct 417 QIALDSARGLEYIHEHTVPVYVHRDIKSANILIDQKFRA-------KVADFGLTKLTEVG 469
Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC---------------FD 810
+ + ++APE + G +S +D + FG L E+ F
Sbjct 470 GSATRGAMGTFGYMAPETVYG---EVSAKVDVYAFGVVLYELISAKGAVVKMTEAVGEFR 526
Query 811 GEAPL--QSRSPSEKEHFYQR------QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
G + +S ++KE ++ P S ++A L C RPS R I
Sbjct 527 GLVGVFEESFKETDKEEALRKIIDPRLGDSYPFDSVYKMAELGKACTQENAQLRPSMRYI 586
Query 863 LRDLTRL 869
+ L+ L
Sbjct 587 VVALSTL 593
>sp|Q9NWZ3|IRAK4_HUMAN Interleukin-1 receptor-associated kinase
4 OS=Homo sapiens OX=9606 GN=IRAK4 PE=1 SV=1
Length=460
Score = 83.2 bits (204), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 68/202 (34%), Positives = 98/202 (49%), Gaps = 19/202 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--DCGPQH-RSGWKQEIDILRTLYHEHI 959
+GEG FG V + T VAVK L A D + + + QEI ++ HE++
Sbjct 192 MGEGGFGVVYKGYVNNTT------VAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENL 245
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLH 1015
++ G D + L LV Y+P GSL D L + AQ G+ +LH
Sbjct 246 VELLGFSSDGDD--LCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLH 303
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLK 1074
H+IHRD+ + N+LLD KI DFGLA+A + R G + + APE L+
Sbjct 304 ENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTA--YMAPEALR 361
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ SD++SFGV L E++T
Sbjct 362 G-EITPKSDIYSFGVVLLEIIT 382
Score = 57.0 bits (136), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 54/243 (22%), Positives = 104/243 (43%), Gaps = 33/243 (14%)
Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
++D + ++ F + +M++ H +L + G G + +V Y+ +G L L
Sbjct 218 MVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCL 277
Query 703 RGHVPMAWKM--VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G P++W M +AQ A+ +++L + +H ++ NILL A K+SD
Sbjct 278 DGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTA-------KISDF 330
Query 761 GVGLGA--LSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ + ++ RI ++APE L G ++ D + FG LLEI A
Sbjct 331 GLARASEKFAQTVMTSRIVGTTAYMAPEALRG---EITPKSDIYSFGVVLLEIITGLPAV 387
Query 815 LQSRSPS---------------EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859
+ R P +++ ++ + S + ++ SQCL + +RP
Sbjct 388 DEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDI 447
Query 860 RTI 862
+ +
Sbjct 448 KKV 450
>sp|O80623|Y2393_ARATH Probable receptor-like protein kinase At2g39360
OS=Arabidopsis thaliana OX=3702 GN=At2g39360 PE=1 SV=1
Length=815
Score = 84.3 bits (207), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 67/205 (33%), Positives = 101/205 (49%), Gaps = 26/205 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHEHI 959
+G G FGKV Y E VAVK PQ R G +K E+++L H H+
Sbjct 493 IGVGGFGKV----YKGVLRDKTE-VAVKR----GAPQSRQGLAEFKTEVEMLTQFRHRHL 543
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQLLLFAQQICEGMAY 1013
+ G C++ E + +V EY+ G+L+D+L PR S Q L G+ Y
Sbjct 544 VSLIGYCDENSE--MIIVYEYMEKGTLKDHLYDLDDKPRLS--WRQRLEICVGAARGLHY 599
Query 1014 LHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
LH + IHRD+ + N+LLD++ + K+ DFGL+K P+ + + V + P
Sbjct 600 LHTGSTRAIIHRDVKSANILLDDNFMAKVADFGLSKTGPDLDQTH-VSTAVKGSFGYLDP 658
Query 1071 ECLKEYKFYYASDVWSFGVTLYELL 1095
E L + SDV+SFGV + E++
Sbjct 659 EYLTRQQLTEKSDVYSFGVVMLEVV 683
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 57/236 (24%), Positives = 94/236 (40%), Gaps = 29/236 (12%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F +++Q H HL + G C E I+V EY+E G L L ++W ++
Sbjct 528 FKTEVEMLTQFRHRHLVSLIGYCDENSEMIIVYEYMEKGTLKDHLYDLDDKPRLSWRQRL 587
Query 713 VVAQQLASALSYL---ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+ A L YL + ++H +V NILL +A+ LS G L
Sbjct 588 EICVGAARGLHYLHTGSTRAIIHRDVKSANILLDDNFMAKVAD--FGLSKTGPDLDQTHV 645
Query 770 EERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
V+ +L PE L L+ D + FG +LE+ G + P EK + +
Sbjct 646 STAVKGSFGYLDPEYLT--RQQLTEKSDVYSFGVVMLEVVC-GRPVIDPSLPREKVNLIE 702
Query 829 ------RQHRLPEPSCPQLA------------TLTSQCLTYEPTQRPSFRTILRDL 866
++ +L + P L +T +CL+ +RP+ +L +L
Sbjct 703 WAMKLVKKGKLEDIIDPFLVGKVKLEEVKKYCEVTEKCLSQNGIERPAMGDLLWNL 758
>sp|A9S5R3|M2K1C_PHYPA Mitogen-activated protein kinase kinase
1c OS=Physcomitrium patens OX=3218 GN=MKK1c PE=3 SV=1
Length=346
Score = 81.6 bits (200), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 77/286 (27%), Positives = 134/286 (47%), Gaps = 24/286 (8%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ +R LG+G G V L + TN A+KA++ + R QE+ I + +
Sbjct 70 LELVRFLGKGAGGTVQLVRHKWTNVN----YALKAIQMNINETVRKQIVQELKINQVTHQ 125
Query 957 E--HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAY 1013
+ +I++ G + +++EY+ GSL D + + I L + A Q+ +G+ Y
Sbjct 126 QCPYIVECFHSFYHNG--VISMILEYMDRGSLSDIIKQQKQIPEPYLAVIASQVLKGLEY 183
Query 1014 LH-AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
LH +H IHRD+ N+L+++ VKI DFG++ + R+ + +PE
Sbjct 184 LHQVRHIIHRDIKPSNLLINHKGEVKISDFGVSAVLVHS---LAQRDTFVGTCTYMSPER 240
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE-LLERG 1131
L+ + Y SD+WS G+TL E C P + G+ +G L E ++ +
Sbjct 241 LQGRSYAYDSDLWSLGLTLLE----CALGTFP----YKPAGMEEGWQNFFILMECIVNQP 292
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEK 1175
PDK E +++C S RP+ +L+ P L+ +E+
Sbjct 293 PAAASPDKFSPEFCSFIESCIRKCPSERPSTTDLLKHPFLQKYNEE 338
Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 50/198 (25%), Positives = 89/198 (45%), Gaps = 32/198 (16%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN-KNLVHGNVCGRNILLA 743
M+ EY++ G L +++++ +P + V+A Q+ L YL ++++H ++ N+L+
Sbjct 145 MILEYMDRGSLSDIIKQQK-QIPEPYLAVIASQVLKGLEYLHQVRHIIHRDIKPSNLLIN 203
Query 744 RLGLAEGTSPFIKLSDPGVGLGAL----SREERVERIPWLAPECLPGGANSLSTAMDKWG 799
G +K+SD GV + R+ V +++PE L G S + D W
Sbjct 204 HKGE-------VKISDFGVSAVLVHSLAQRDTFVGTCTYMSPERLQG--RSYAYDSDLWS 254
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-------------PEPSCPQLATLTS 846
G TLLE C G P + P+ E +Q L P+ P+ +
Sbjct 255 LGLTLLE-CALGTFPYK---PAGMEEGWQNFFILMECIVNQPPAAASPDKFSPEFCSFIE 310
Query 847 QCLTYEPTQRPSFRTILR 864
C+ P++RPS +L+
Sbjct 311 SCIRKCPSERPSTTDLLK 328
>sp|Q8LST2|WNK7_ARATH Probable serine/threonine-protein kinase
WNK7 OS=Arabidopsis thaliana OX=3702 GN=WNK7 PE=2 SV=1
Length=557
Score = 83.6 bits (205), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 73/276 (26%), Positives = 132/276 (48%), Gaps = 26/276 (9%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD---CG 937
+P+ DPT RY++ +G+G K +D + G VA ++ D
Sbjct 15 DPEVLEIDPTC---RYIRYKEVIGKGA-SKTVFKGFDEVD---GIEVAWNQVRIDDLLQS 67
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIG 996
P E+ +L++L H++II++ D K++ ++ E GSLR Y +H +
Sbjct 68 PDCLERLYSEVRLLKSLKHKNIIRFYNSWIDDKNKTVNIITELFTSGSLRQYRKKHRKVN 127
Query 997 LAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFGLAKAVPEGHE 1053
+ + +A+QI G+ YLH+Q IHRD+ N+ ++ N VKIGD GLA + + +
Sbjct 128 MKAVKCWARQILTGLKYLHSQDPPIIHRDIKCDNIFINGNHGEVKIGDLGLATVMEQANA 187
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFL 1109
+ +P F APE E + +D++SFG+ + E++T +C+ S
Sbjct 188 KSVI----GTPEFM-APELYDE-NYNELADIYSFGMCMLEMVTFEYPYCECRNSAQIYKK 241
Query 1110 ELIGIAQGQMTVLRLTELLERGER--LPRPDKCPCE 1143
GI ++ ++ E+++ E+ LP ++ E
Sbjct 242 VSSGIKPASLSKVKDPEVMKFIEKCLLPASERLSAE 277
>sp|P47735|RLK5_ARATH Receptor-like protein kinase 5 OS=Arabidopsis
thaliana OX=3702 GN=RLK5 PE=1 SV=1
Length=999
Score = 84.3 bits (207), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 63/191 (33%), Positives = 92/191 (48%), Gaps = 20/191 (10%)
Query 924 GEMVAVKALKADC---------GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
GE+VAVK L +R + E++ L T+ H+ I++ CC G+ L
Sbjct 705 GEVVAVKKLNKSVKGGDDEYSSDSLNRDVFAAEVETLGTIRHKSIVRLWCCCS-SGDCKL 763
Query 975 QLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAA 1026
LV EY+P GSL D L +G + L A EG++YLH +HRD+ +
Sbjct 764 -LVYEYMPNGSLADVLHGDRKGGVVLGWPERLRIALDAAEGLSYLHHDCVPPIVHRDVKS 822
Query 1027 RNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
N+LLD+D K+ DFG+AK G + + APE + + SD++
Sbjct 823 SNILLDSDYGAKVADFGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEKSDIY 882
Query 1086 SFGVTLYELLT 1096
SFGV L EL+T
Sbjct 883 SFGVVLLELVT 893
>sp|O04086|Y1105_ARATH Probable receptor-like protein kinase At1g11050
OS=Arabidopsis thaliana OX=3702 GN=At1g11050 PE=2 SV=1
Length=625
Score = 84.0 bits (206), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 73/268 (27%), Positives = 118/268 (44%), Gaps = 25/268 (9%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGC--CEDQGEKSLQLVMEYV 981
G ++AVK + + Q + ++ E++I+ L H +++ +GC +D E LV +Y+
Sbjct 317 GSVIAVKKV-IESEFQGDAEFRNEVEIISNLKHRNLVPLRGCSMVDDDSESQRYLVYDYM 375
Query 982 PLGSLRDYL-PRHS-----IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLD 1032
G+L D+L PR + Q + +G+AYLH HRD+ N+LLD
Sbjct 376 SNGNLDDHLFPRGETTKMPLSWPQRKSIILDVAKGLAYLHYGVKPAIYHRDIKGTNILLD 435
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
D ++ DFGLAK EG + R G + APE + SDV+SFGV +
Sbjct 436 VDMRARVADFGLAKQSREGESHLTTRVAGTHG--YLAPEYALYGQLTEKSDVYSFGVVIL 493
Query 1093 ELLTHCD----SSQSPPTKFL------ELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
E++ S+ P FL L+ + + L + L E G L P
Sbjct 494 EIMCGRKALDLSTSGSPNTFLITDWAWSLVKAGKTE-EALEQSLLREEGSGLSNPKGIME 552
Query 1143 EVYHLMKNCWETEASFRPTFENLIPILK 1170
+ C + RPT + + +L+
Sbjct 553 RFLQVGILCAHVLVALRPTILDALKMLE 580
>sp|Q08942|NRKA_TRYBB Putative serine/threonine-protein kinase
A OS=Trypanosoma brucei brucei OX=5702 GN=NRKA PE=2 SV=1
Length=431
Score = 82.8 bits (203), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 81/292 (28%), Positives = 127/292 (43%), Gaps = 52/292 (18%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ-EIDILRT 953
+YL K +G G +G+ Y + DG+ + K + Q + Q EI L
Sbjct 19 KYLNK-GIVGLGSYGEA--YVAESVEDGS--LCVAKVMDLSKMSQRDKRYAQSEIKCLAN 73
Query 954 LYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIGLAQ-------LLLFAQ 1005
H +II+Y ED E L +VME+ G+L + + G A+ L LF Q
Sbjct 74 CNHPNIIRY---IEDHEENDRLLIVMEFADSGNLDEQIKLRGSGDARYFQEHEALFLFLQ 130
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
+C + Y+H+ +HRD+ + NVLL + LVK+GDFG + H+Y ED S V
Sbjct 131 -LCLALDYIHSHKMLHRDIKSANVLLTSTGLVKLGDFGFS------HQY----EDTVSGV 179
Query 1066 ---------FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
++ APE ++ +DVWS GV LYE++ P L G+
Sbjct 180 VASTFCGTPYYLAPELWNNKRYNKKADVWSLGVLLYEIM-----GMKKPFSASNLKGL-- 232
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
++++L G P PD E ++ + + RP+ + I
Sbjct 233 -------MSKVLA-GTYAPLPDSFSSEFKRVVDGILVADPNDRPSVREIFQI 276
>sp|Q92241|PHO85_KLULA Negative regulator of the PHO system OS=Kluyveromyces
lactis (strain ATCC 8585 / CBS 2359 / DSM 70799
/ NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=PHO85 PE=3
SV=2
Length=304
Score = 80.9 bits (198), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 59/208 (28%), Positives = 100/208 (48%), Gaps = 20/208 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
K++ +G G + V Y N TG VA+K +K D S +EI +++ L H
Sbjct 7 FKQLEKVGNGTYATV----YKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKH 62
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFAQQICE 1009
++I++ E L LV E++ L+ ++ + G + + F Q+ +
Sbjct 63 DNIVRLFDVI--HTENKLTLVFEFMD-NDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 119
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068
G+A+ H +HRDL +N+L++N +K+GDFGLA+A + + WY
Sbjct 120 GVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFS----SEVVTLWYR 175
Query 1069 APECLKEYKFYYAS-DVWSFGVTLYELL 1095
AP+ L + Y S D+WS G L E++
Sbjct 176 APDVLMGSRNYCTSIDIWSCGCILAEMI 203
Score = 41.2 bits (95), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 65/304 (21%), Positives = 116/304 (38%), Gaps = 50/304 (16%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--VLD 645
+ QL +G GT VY+G + G + V LK LD
Sbjct 6 QFKQLEKVGNGTYATVYKGLNKTTG------------------------VYVALKEVKLD 41
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ A E SLM ++ H ++ + V + +V E++++ R +G+
Sbjct 42 SEEGTPSTAIREI-SLMKELKHDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGN 100
Query 706 VPMAWKMVVAQ----QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
+M + + QL +++ ++H ++ +N+L+ G +KL D G
Sbjct 101 SHKGLEMDLVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQ-------LKLGDFG 153
Query 762 V----GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ G+ + V + + AP+ L G N T++D W G L E+ S
Sbjct 154 LARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN-YCTSIDIWSCGCILAEMIMGKPLFPGS 212
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
+ + + E + PQ+ +Q Y P P RDL +L +N +V
Sbjct 213 NDEEQLKLIFDTMGTPVEQTWPQV----TQLAKYNPLLPPHMP---RDLKQLLQNNTEEV 265
Query 878 LTVN 881
L N
Sbjct 266 LDDN 269
>sp|Q9LEU7|CIPK5_ARATH CBL-interacting serine/threonine-protein
kinase 5 OS=Arabidopsis thaliana OX=3702 GN=CIPK5 PE=1 SV=1
Length=445
Score = 82.8 bits (203), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 68/208 (33%), Positives = 104/208 (50%), Gaps = 23/208 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD---CGPQHRSGWKQEIDILRTLYHE 957
R LG+G F KV Y GE VA+K + D P K+EI I++ + H
Sbjct 16 RLLGKGTFAKV----YYGKEIIGGECVAIKVINKDQVMKRPGMMEQIKREISIMKLVRHP 71
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+I++ K + + + VME+V G L + + + + QQ+ + Y H++
Sbjct 72 NIVELKEVMATKTK--IFFVMEFVKGGELFCKISKGKLHEDAARRYFQQLISAVDYCHSR 129
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG------DSPVFWYAPE 1071
HRDL N+LLD + +KI DFGL+ A+PE ++ +DG +P + APE
Sbjct 130 GVSHRDLKPENLLLDENGDLKISDFGLS-ALPE-----QILQDGLLHTQCGTPAY-VAPE 182
Query 1072 CLKEYKFYYA-SDVWSFGVTLYELLTHC 1098
LK+ + A +D+WS GV LY LL C
Sbjct 183 VLKKKGYDGAKADIWSCGVVLYVLLAGC 210
Score = 43.9 bits (102), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 52/214 (24%), Positives = 88/214 (41%), Gaps = 22/214 (10%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M V H ++ + V + V E+V+ G L + + + H A + QQL
Sbjct 63 SIMKLVRHPNIVELKEVMATKTKIFFVMEFVKGGELFCKISKGKLHEDAARRYF--QQLI 120
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776
SA+ Y ++ + H ++ N+LL G +K+SD GL AL + + +
Sbjct 121 SAVDYCHSRGVSHRDLKPENLLLDENGD-------LKISD--FGLSALPEQILQDGLLHT 171
Query 777 -----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQ 830
++APE L + A D W G L + G P Q + + ++
Sbjct 172 QCGTPAYVAPEVLKKKGYDGAKA-DIWSCGVVLY-VLLAGCLPFQDENLMNMYRKIFRAD 229
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
P P+ L S+ L +P +R S I+R
Sbjct 230 FEFPPWFSPEARRLISKLLVVDPDRRISIPAIMR 263
>sp|Q9Z1W9|STK39_MOUSE STE20/SPS1-related proline-alanine-rich
protein kinase OS=Mus musculus OX=10090 GN=Stk39 PE=1 SV=1
Length=556
Score = 83.6 bits (205), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 75/256 (29%), Positives = 116/256 (45%), Gaps = 24/256 (9%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
E VA+K + + +EI + H +++ Y + E L LVM+ + G
Sbjct 99 ERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDE--LWLVMKLLSGG 156
Query 985 SLRDYLP------RHSIGLAQLLLFA---QQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035
S+ D + H G+ + + A +++ EG+ YLH IHRDL A N+LL D
Sbjct 157 SMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDG 216
Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092
V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T
Sbjct 217 SVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAI 276
Query 1093 ELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERG-ERLPRPDKCPCEVYHLMKN 1150
EL T + PP K L L T+ LE G E K L+
Sbjct 277 ELATGAAPYHKYPPMKVLML--------TLQNDPPTLETGVEDKEMMKKYGKSFRKLLSL 328
Query 1151 CWETEASFRPTFENLI 1166
C + + S RPT L+
Sbjct 329 CLQKDPSKRPTAAELL 344
Score = 40.0 bits (92), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 53/227 (23%), Positives = 89/227 (39%), Gaps = 30/227 (13%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWL------RRERGHVPMAWKMVV 714
MSQ SH ++ + V E +V + + G LD+ + G + A +
Sbjct 125 MSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATI 184
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALSRE 770
+++ L YL +H ++ NILL G + G S F L+ G R+
Sbjct 185 LKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAF--LATGGDVTRNKVRK 242
Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------LQS 817
V W+APE + D W FG T +E+ G AP LQ+
Sbjct 243 TFVGTPCWMAPEVME-QVRGYDFKADMWSFGITAIELA-TGAAPYHKYPPMKVLMLTLQN 300
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
P+ + ++ + + L S CL +P++RP+ +L+
Sbjct 301 DPPTLETGVEDKE--MMKKYGKSFRKLLSLCLQKDPSKRPTAAELLK 345
>sp|O14427|CLA4_CANAX Serine/threonine-protein kinase CLA4 OS=Candida
albicans OX=5476 GN=CLA4 PE=3 SV=1
Length=971
Score = 84.3 bits (207), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 58/204 (28%), Positives = 100/204 (49%), Gaps = 10/204 (5%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
K + + G+G G V L N+ +A+K + D P+ + EI +++
Sbjct 677 KPLFRIVEKAGQGASGNVYLAEMIKDNN---RKIAIKQMDLDAQPR-KELIINEILVMKD 732
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGM 1011
H++I+ + G+ L ++MEY+ GSL + + + L Q+ + +G+
Sbjct 733 SQHKNIVNFLDSYL-IGDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIATICFETLKGL 791
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
+LH +H IHRD+ + NVLLD VKI DFG + + R G +P +W APE
Sbjct 792 QHLHKKHIIHRDIKSDNVLLDAYGNVKITDFGFCAKLTD-QRNKRATMVG-TP-YWMAPE 848
Query 1072 CLKEYKFYYASDVWSFGVTLYELL 1095
+K+ ++ DVWS G+ E++
Sbjct 849 VVKQKEYDEKVDVWSLGIMTIEMI 872
Score = 35.8 bits (81), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 34/167 (20%), Positives = 67/167 (40%), Gaps = 19/167 (11%)
Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
+M H ++ F+ + E ++ EY++ G L + + + +
Sbjct 729 VMKDSQHKNIVNFLDSYLIGDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIATICFETL 788
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777
L +L K+++H ++ N+LL G +K++D G A ++R +R
Sbjct 789 KGLQHLHKKHIIHRDIKSDNVLLDAYG-------NVKITD--FGFCAKLTDQRNKRATMV 839
Query 778 ----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
W+APE + +D W G +E+ +GE P + P
Sbjct 840 GTPYWMAPEVV--KQKEYDEKVDVWSLGIMTIEM-IEGEPPYLNEEP 883
>sp|Q54B33|PAKE_DICDI Serine/threonine-protein kinase pakE OS=Dictyostelium
discoideum OX=44689 GN=pakE PE=3 SV=1
Length=926
Score = 84.3 bits (207), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 54/194 (28%), Positives = 101/194 (52%), Gaps = 12/194 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G +G V + TN +A+K L P ++EID+L+ +++ Y
Sbjct 656 LGQGGYGAVFKVLHRETNFP----LAIKVLS--ITPTRIKDIEKEIDLLKKCRCPNVLSY 709
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G + + L ++M++ +GS+ D + ++ Q+ + + G+ YLH++ +
Sbjct 710 YGSISSKLTE-LWILMDHCAVGSINDMMKICCDTLDEEQIAVVTLNVLNGLGYLHSKGIV 768
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
H D+ A N+LL D+ +KI DFG+++ + EY + SP++ APE + + +
Sbjct 769 HLDVKAANILLTEDKQIKIADFGVSQQL--QTEYGQANVYIGSPLYM-APEVILKAPYNS 825
Query 1081 ASDVWSFGVTLYEL 1094
+D+WS G+TL EL
Sbjct 826 KADIWSLGITLIEL 839
Score = 39.7 bits (91), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 42/166 (25%), Positives = 66/166 (40%), Gaps = 32/166 (19%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
VV + + L YL +K +VH +V NILL IK++D GV L E
Sbjct 750 VVTLNVLNGLGYLHSKGIVHLDVKAANILLTE-------DKQIKIADFGVS-QQLQTEYG 801
Query 773 VERI-----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
+ ++APE + ++ D W G TL+E+ + R P+
Sbjct 802 QANVYIGSPLYMAPEVILKAP--YNSKADIWSLGITLIELA-------EGRPPNRGLRSM 852
Query 828 QRQHRLPEPSCPQLA----------TLTSQCLTYEPTQRPSFRTIL 863
+ +P P+L+ + CL +P QRPS +L
Sbjct 853 NQLVEIPNMPPPKLSNPKDWSPCFNNFLATCLVKDPVQRPSVIDLL 898
>sp|Q5APR8|CLA4_CANAL Serine/threonine-protein kinase CLA4 OS=Candida
albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=CLA4
PE=1 SV=1
Length=976
Score = 84.3 bits (207), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 57/198 (29%), Positives = 98/198 (49%), Gaps = 10/198 (5%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ G+G G V L N+ +A+K + D P+ + EI +++ H++I
Sbjct 688 VEKAGQGASGNVYLAEMIKDNN---RKIAIKQMDLDAQPR-KELIINEILVMKDSQHKNI 743
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQ 1017
+ + G+ L ++MEY+ GSL + + + L Q+ + +G+ +LH +
Sbjct 744 VNFLDSYL-IGDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIATICFETLKGLQHLHKK 802
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
H IHRD+ + NVLLD VKI DFG + + R G +P +W APE +K+ +
Sbjct 803 HIIHRDIKSDNVLLDAYGNVKITDFGFCAKLTD-QRNKRATMVG-TP-YWMAPEVVKQKE 859
Query 1078 FYYASDVWSFGVTLYELL 1095
+ DVWS G+ E++
Sbjct 860 YDEKVDVWSLGIMTIEMI 877
Score = 35.8 bits (81), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 34/167 (20%), Positives = 67/167 (40%), Gaps = 19/167 (11%)
Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
+M H ++ F+ + E ++ EY++ G L + + + +
Sbjct 734 VMKDSQHKNIVNFLDSYLIGDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIATICFETL 793
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777
L +L K+++H ++ N+LL G +K++D G A ++R +R
Sbjct 794 KGLQHLHKKHIIHRDIKSDNVLLDAYG-------NVKITD--FGFCAKLTDQRNKRATMV 844
Query 778 ----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
W+APE + +D W G +E+ +GE P + P
Sbjct 845 GTPYWMAPEVV--KQKEYDEKVDVWSLGIMTIEM-IEGEPPYLNEEP 888
>sp|Q9UEW8|STK39_HUMAN STE20/SPS1-related proline-alanine-rich
protein kinase OS=Homo sapiens OX=9606 GN=STK39 PE=1 SV=3
Length=545
Score = 83.6 bits (205), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 62/200 (31%), Positives = 98/200 (49%), Gaps = 15/200 (8%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
E VA+K + + +EI + H +++ Y + E L LVM+ + G
Sbjct 87 ERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDE--LWLVMKLLSGG 144
Query 985 SLRDYLP------RHSIGLAQLLLFA---QQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035
S+ D + H G+ + + A +++ EG+ YLH IHRDL A N+LL D
Sbjct 145 SMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDG 204
Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092
V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T
Sbjct 205 SVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAI 264
Query 1093 ELLTHCDS-SQSPPTKFLEL 1111
EL T + PP K L L
Sbjct 265 ELATGAAPYHKYPPMKVLML 284
Score = 39.7 bits (91), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 53/227 (23%), Positives = 89/227 (39%), Gaps = 30/227 (13%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWL------RRERGHVPMAWKMVV 714
MSQ SH ++ + V E +V + + G LD+ + G + A +
Sbjct 113 MSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATI 172
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALSRE 770
+++ L YL +H ++ NILL G + G S F L+ G R+
Sbjct 173 LKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAF--LATGGDVTRNKVRK 230
Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------LQS 817
V W+APE + D W FG T +E+ G AP LQ+
Sbjct 231 TFVGTPCWMAPEVME-QVRGYDFKADMWSFGITAIELA-TGAAPYHKYPPMKVLMLTLQN 288
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
P+ + ++ + + L S CL +P++RP+ +L+
Sbjct 289 DPPTLETGVEDKE--MMKKYGKSFRKLLSLCLQKDPSKRPTAAELLK 333
>sp|O88506|STK39_RAT STE20/SPS1-related proline-alanine-rich protein
kinase OS=Rattus norvegicus OX=10116 GN=Stk39 PE=1 SV=2
Length=553
Score = 83.6 bits (205), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 75/256 (29%), Positives = 116/256 (45%), Gaps = 24/256 (9%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
E VA+K + + +EI + H +++ Y + E L LVM+ + G
Sbjct 96 ERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDE--LWLVMKLLSGG 153
Query 985 SLRDYLP------RHSIGLAQLLLFA---QQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035
S+ D + H G+ + + A +++ EG+ YLH IHRDL A N+LL D
Sbjct 154 SMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDG 213
Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092
V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T
Sbjct 214 SVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAI 273
Query 1093 ELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERG-ERLPRPDKCPCEVYHLMKN 1150
EL T + PP K L L T+ LE G E K L+
Sbjct 274 ELATGAAPYHKYPPMKVLML--------TLQNDPPTLETGVEDKEMMKKYGKSFRKLLSL 325
Query 1151 CWETEASFRPTFENLI 1166
C + + S RPT L+
Sbjct 326 CLQKDPSKRPTAAELL 341
Score = 39.7 bits (91), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 53/227 (23%), Positives = 89/227 (39%), Gaps = 30/227 (13%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWL------RRERGHVPMAWKMVV 714
MSQ SH ++ + V E +V + + G LD+ + G + A +
Sbjct 122 MSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATI 181
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALSRE 770
+++ L YL +H ++ NILL G + G S F L+ G R+
Sbjct 182 LKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAF--LATGGDVTRNKVRK 239
Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------LQS 817
V W+APE + D W FG T +E+ G AP LQ+
Sbjct 240 TFVGTPCWMAPEVME-QVRGYDFKADMWSFGITAIELA-TGAAPYHKYPPMKVLMLTLQN 297
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
P+ + ++ + + L S CL +P++RP+ +L+
Sbjct 298 DPPTLETGVEDKE--MMKKYGKSFRKLLSLCLQKDPSKRPTAAELLK 342
>sp|F4JEQ2|PBL23_ARATH Probable serine/threonine-protein kinase
PBL23 OS=Arabidopsis thaliana OX=3702 GN=PBL23 PE=2 SV=1
Length=386
Score = 82.0 bits (201), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 68/203 (33%), Positives = 100/203 (49%), Gaps = 17/203 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG+V Y + ++VAVK L + G Q + E+ +L L+H++++
Sbjct 88 LGEGGFGRV----YKGQIETPEQVVAVKQLDRN-GYQGNREFLVEVMMLSLLHHQNLVNL 142
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQLLLFAQQICEGMAYLHA 1016
G C D G++ + LV EY+ GSL D+L + + + A G+ YLH
Sbjct 143 VGYCAD-GDQRI-LVYEYMQNGSLEDHLLELARNKKKPLDWDTRMKVAAGAARGLEYLHE 200
Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
I+RD A N+LLD + K+ DFGLAK P G E + V + APE
Sbjct 201 TADPPVIYRDFKASNILLDEEFNPKLSDFGLAKVGPTGGETH-VSTRVMGTYGYCAPEYA 259
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
+ SDV+SFGV E++T
Sbjct 260 LTGQLTVKSDVYSFGVVFLEMIT 282
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 66/262 (25%), Positives = 107/262 (41%), Gaps = 40/262 (15%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD-- 696
V +K LD + + F ++S + H +L + G C G + I+V EY+++G L+
Sbjct 108 VAVKQLDRNGYQGNREFLVEVMMLSLLHHQNLVNLVGYCADGDQRILVYEYMQNGSLEDH 167
Query 697 -VWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEG 750
+ L R + P+ W +M VA A L YL +++ + NIL L E
Sbjct 168 LLELARNKKK-PLDWDTRMKVAAGAARGLEYLHETADPPVIYRDFKASNIL-----LDEE 221
Query 751 TSPFIKLSDPGVG-LGALSREERVE-RIPWLAPECLPGGA--NSLSTAMDKWGFGATLLE 806
+P KLSD G+ +G E V R+ C P A L+ D + FG LE
Sbjct 222 FNP--KLSDFGLAKVGPTGGETHVSTRVMGTYGYCAPEYALTGQLTVKSDVYSFGVVFLE 279
Query 807 ICFDGEAPLQSRSPSEKEH--------FYQRQH-----------RLPEPSCPQLATLTSQ 847
+ G + + P+E+++ F R+ + P Q + +
Sbjct 280 M-ITGRRVIDTTKPTEEQNLVTWASPLFKDRRKFTLMADPLLEGKYPIKGLYQALAVAAM 338
Query 848 CLTYEPTQRPSFRTILRDLTRL 869
CL E RP ++ L L
Sbjct 339 CLQEEAATRPMMSDVVTALEYL 360
>sp|Q12263|GIN4_YEAST Serine/threonine-protein kinase GIN4 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=GIN4 PE=1 SV=1
Length=1142
Score = 84.3 bits (207), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 73/217 (34%), Positives = 103/217 (47%), Gaps = 38/217 (18%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGW---------------KQ 946
LG G GKV L N TG+ AVK + KA + SG ++
Sbjct 25 LGLGSTGKVQL----ARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIER 80
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL------RDYLPRHSIGLAQL 1000
EI I++ L H ++++ E + L LV+EY G L R LP H +
Sbjct 81 EIIIMKLLNHPNVLRLYDVWETNTD--LYLVLEYAEKGELFNLLVERGPLPEH-----EA 133
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+ F +QI G++Y HA +HRDL N+LLD+ +KI DFG+A EG ++ E
Sbjct 134 IRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEG----KLLET 189
Query 1061 GDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLT 1096
+ APE + + +ASDVWS GV L+ LLT
Sbjct 190 SCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLT 226
>sp|A8X5H5|GSK3_CAEBR Glycogen synthase kinase-3 OS=Caenorhabditis
briggsae OX=6238 GN=gsk-3 PE=3 SV=1
Length=359
Score = 81.6 bits (200), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 69/209 (33%), Positives = 103/209 (49%), Gaps = 35/209 (17%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V L TN EMVA+K + D ++R E+ I+R L H +I+K
Sbjct 42 IGNGSFGVVFLAKLSTTN----EMVAIKKVLQDKRFKNR-----ELQIMRKLNHPNIVKL 92
Query 963 KGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRH------SIGLAQLLLFAQQICEGMA 1012
K G+K L L++EYVP R + RH SI + + L+ Q+ +A
Sbjct 93 KYFFYSSGDKKDELYLNLILEYVPETVYR--VARHYSKQRQSIPMIYVKLYMYQLLRSLA 150
Query 1013 YLHAQHYIHRDLAARNVLLDNDR-LVKIGDFGLAKAVPEGHEYYRVREDGDSPV----FW 1067
Y+H+ HRD+ +N+L+D + ++K+ DFG AK Y VR + + ++
Sbjct 151 YIHSIGICHRDIKPQNLLIDPETGILKLCDFGSAK--------YLVRNEPNVSYICSRYY 202
Query 1068 YAPECLKEYKFYYAS-DVWSFGVTLYELL 1095
APE + Y S DVWS G + ELL
Sbjct 203 RAPELIFGATNYTNSIDVWSAGTVIAELL 231
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 65/323 (20%), Positives = 133/323 (41%), Gaps = 66/323 (20%)
Query 573 TLNLSQLSFHRVDQK-EITQLSH--LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
T+ ++ ++ VDQ+ EI+ +G G+ V+ +L + + D+
Sbjct 17 TMVVASVATDGVDQQVEISYYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKVLQDK----- 71
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
R + +EL+++ K+ P+ + FY + ++ +++ + PE V
Sbjct 72 -RFKNRELQIMRKLNHPNIVKLKYFFYSSGDKKDEL------YLNLILEYVPET--VYRV 122
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
H ++R +PM + + QL +L+Y+ + + H ++ +N+L+ +
Sbjct 123 ARH------YSKQRQSIPMIYVKLYMYQLLRSLAYIHSIGICHRDIKPQNLLI------D 170
Query 750 GTSPFIKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+ +KL D G + E V I + APE + G N + ++D W G + E
Sbjct 171 PETGILKLCDFGSAKYLVRNEPNVSYICSRYYRAPELIFGATN-YTNSIDVWSAGTVIAE 229
Query 807 I-----CFDGEA------------------PLQSRSPSEKE--------HFYQRQHRLPE 835
+ F G++ +QS +P+ KE H + + R+
Sbjct 230 LLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIQSMNPNYKEFKFPQIKAHPWNKVFRVHT 289
Query 836 PSCPQLATLTSQCLTYEPTQRPS 858
P+ + L S+ + Y PT RP+
Sbjct 290 PA--EAIDLISKIIEYTPTSRPT 310
>sp|Q8C078|KKCC2_MOUSE Calcium/calmodulin-dependent protein kinase
kinase 2 OS=Mus musculus OX=10090 GN=Camkk2 PE=1 SV=2
Length=588
Score = 83.6 bits (205), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 52/150 (35%), Positives = 77/150 (51%), Gaps = 6/150 (4%)
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ 1005
QEI IL+ L H +++K +D E L +V E V G + + + Q + Q
Sbjct 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQ 294
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
+ +G+ YLH Q IHRD+ N+L+ D +KI DFG++ +G + G +P
Sbjct 295 DLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF-KGSDALLSNTVG-TPA 352
Query 1066 FWYAPECLKEYKFYY---ASDVWSFGVTLY 1092
F APE L E + + A DVW+ GVTLY
Sbjct 353 FM-APESLSETRKIFSGKALDVWAMGVTLY 381
>sp|Q15131|CDK10_HUMAN Cyclin-dependent kinase 10 OS=Homo sapiens
OX=9606 GN=CDK10 PE=1 SV=1
Length=360
Score = 81.6 bits (200), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 70/214 (33%), Positives = 101/214 (47%), Gaps = 26/214 (12%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDI 950
+ +K+ +GEG +G V Y + T E+VA+K ++ D + + G +EI +
Sbjct 37 KEFEKLNRIGEGTYGIV----YRARDTQTDEIVALKKVRMD---KEKDGIPISSLREITL 89
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQIC 1008
L L H +I++ K +S+ LVM Y L SL + +P AQ+ Q+
Sbjct 90 LLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPT-PFSEAQVKCIVLQVL 148
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP---V 1065
G+ YLH IHRDL N+L+ + VK DFGLA+A Y V +P
Sbjct 149 RGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARA-------YGVPVKPMTPKVVT 201
Query 1066 FWY-APECLKEYKFYYAS-DVWSFGVTLYELLTH 1097
WY APE L S D+W+ G L ELL H
Sbjct 202 LWYRAPELLLGTTTQTTSIDMWAVGCILAELLAH 235
>sp|C0LGI2|Y1677_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g67720 OS=Arabidopsis thaliana OX=3702
GN=At1g67720 PE=1 SV=1
Length=929
Score = 84.3 bits (207), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 66/203 (33%), Positives = 98/203 (48%), Gaps = 17/203 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+ +G G FG V Y DG + VAVK + AD + E+ +L ++H +++
Sbjct 610 KKVGRGSFGSV---YYGRMKDG--KEVAVK-ITADPSSHLNRQFVTEVALLSRIHHRNLV 663
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA 1016
G CE+ + L V EY+ GSL D+L S + L AQ +G+ YLH
Sbjct 664 PLIGYCEEADRRIL--VYEYMHNGSLGDHLHGSSDYKPLDWLTRLQIAQDAAKGLEYLHT 721
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRD+ + N+LLD + K+ DFGL++ E + V V + PE
Sbjct 722 GCNPSIIHRDVKSSNILLDINMRAKVSDFGLSRQTEE--DLTHVSSVAKGTVGYLDPEYY 779
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
+ SDV+SFGV L+ELL+
Sbjct 780 ASQQLTEKSDVYSFGVVLFELLS 802
Score = 56.6 bits (135), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 59/233 (25%), Positives = 101/233 (43%), Gaps = 45/233 (19%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
+G+G+ +VY GR++ G+E+ V + DPS H +
Sbjct 612 VGRGSFGSVYYGRMK-----------------------DGKEVAVKITA-DPSSH-LNRQ 646
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F +L+S++ H +L + G C I+V EY+ +G L L + P+ W ++
Sbjct 647 FVTEVALLSRIHHRNLVPLIGYCEEADRRILVYEYMHNGSLGDHLHGSSDYKPLDWLTRL 706
Query 713 VVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA--- 766
+AQ A L YL N +++H +V NILL + K+SD G+
Sbjct 707 QIAQDAAKGLEYLHTGCNPSIIHRDVKSSNILL-------DINMRAKVSDFGLSRQTEED 759
Query 767 LSREERVER--IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
L+ V + + +L PE + L+ D + FG L E+ G+ P+ +
Sbjct 760 LTHVSSVAKGTVGYLDPEYY--ASQQLTEKSDVYSFGVVLFEL-LSGKKPVSA 809
>sp|O13839|FIN1_SCHPO G2-specific protein kinase fin1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=fin1
PE=3 SV=1
Length=722
Score = 84.0 bits (206), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 75/307 (24%), Positives = 133/307 (43%), Gaps = 55/307 (18%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG++ Y G ++A K + + Q + E++ILR L H +I++
Sbjct 10 IGHGSFGRI----YKVQRLKDGALLAQKEIHFGNITRQEKQYIADEVNILRNLKHPNIVQ 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLH- 1015
Y G ++ + + L MEY G L + + R+ ++L F Q+ + H
Sbjct 66 YCGEELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLLLALYRCHY 125
Query 1016 ------------------AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
Q +HRD+ N+ LD + VK+GDFGL+K + +
Sbjct 126 GENAPACDSQWPREIFHPKQSVLHRDIKPANIFLDENNSVKLGDFGLSKLLDNTRVF--T 183
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE--LLTHCDSSQSPPTKFLELI-GI 1114
+ +P ++ +PE ++ + SDVW+ G ++E +LTH +S +LEL I
Sbjct 184 QSYVGTP-YYMSPEIIRSSPYSAKSDVWALGCVIFEICMLTHPFEGRS----YLELQRNI 238
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTV 1172
QG ++ +V+ L+++C E + RPT L+ PIL +
Sbjct 239 CQGNLSCW--------------DHHYSDDVFLLIRHCLEVNSDLRPTTYQLLRSPILSDI 284
Query 1173 HEKYQGQ 1179
K + +
Sbjct 285 RSKLESE 291
>sp|O64778|Y1142_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61420 OS=Arabidopsis thaliana OX=3702
GN=At1g61420 PE=3 SV=2
Length=807
Score = 84.0 bits (206), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 68/204 (33%), Positives = 102/204 (50%), Gaps = 22/204 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG P G G+ +AVK L + G Q + + EI ++ L H+++
Sbjct 500 LGQGGFG--------PVYKGKLQDGKEIAVKRLSSSSG-QGKEEFMNEIVLISKLQHKNL 550
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015
++ GCC +GE+ L L+ E++ SL +L R I + L Q I G+ YLH
Sbjct 551 VRILGCCI-EGEEKL-LIYEFMLNNSLDTFLFDSRKRLEIDWPKRLDIIQGIARGIHYLH 608
Query 1016 AQHY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+ IHRDL N+LLD KI DFGLA+ + +G EY + + APE
Sbjct 609 RDSHLKVIHRDLKVSNILLDEKMNPKISDFGLAR-MYQGTEYQDNTRRVVGTLGYMAPEY 667
Query 1073 LKEYKFYYASDVWSFGVTLYELLT 1096
F SD++SFGV + E+++
Sbjct 668 AWTGMFSEKSDIYSFGVLMLEIIS 691
>sp|Q552C6|ZAK2_DICDI Dual specificity protein kinase zak2 OS=Dictyostelium
discoideum OX=44689 GN=zak2 PE=1 SV=1
Length=635
Score = 83.6 bits (205), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 124/524 (24%), Positives = 208/524 (40%), Gaps = 112/524 (21%)
Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALSREERV 773
L LS+L ++H ++ NI+L + G+ + G+S + D G + S
Sbjct 108 LTETLSFLHKHQILHRDIKPSNIILDKNGVLKLIDFGSSIIDQQQDDGDNICKESSFAIT 167
Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-------FDGEAPLQSRSPSEKEHF 826
++APE + + D W G T+LEI FDG P+
Sbjct 168 GTHTYMAPEV--KKLHRSTKKSDVWSLGCTVLEIVGGNPKKIFDG-IPI----------- 213
Query 827 YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL--RDLTRLQPHNLADVLTVNP-- 882
+P + +CL +P +R +L R ++ + N + P
Sbjct 214 ------IPNHVSEIMVDFIKRCLIIDPNKRSHMEELLTHRLISSMVGQNKNRENNIEPKF 267
Query 883 --DSPASD-PTVFHKRY-----------LKKIRDL---GEGHFGKVSLYCYDPTNDGTGE 925
D +S P F R+ LK +D G+G F V Y+ T
Sbjct 268 NNDYLSSKFPERFAPRFEKPKWEIEFNELKFNKDDTVGGDGFFSVVKKGYYNETE----- 322
Query 926 MVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGCCE--DQGEKSLQLVMEYV 981
VA+K +K G + E+ I+ L H +I+++ C D E + +V E++
Sbjct 323 -VAIKLIKKAHGENVTVCDTFYHEVLIISNLRHPNIVQFIAACIKFDNKEVNHCIVSEWM 381
Query 982 PLGSLRDYLPRHSIGL-------AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL--- 1031
G+L ++ L ++LL I +GM Y H Q IHRDL + NVLL
Sbjct 382 SGGNLSQFISNERKILEINPHLRVKILL---DIAKGMLYSHRQGIIHRDLTSNNVLLNFR 438
Query 1032 -----------------DNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
D+D ++ K+ DFGL+ E ++R G S + + APE L
Sbjct 439 KKKLLNNNSSNNDEQFYDSDEIIAKVCDFGLSSNQSESK---KLR--GGS-IHYMAPENL 492
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
SD++SFG+ ++++ ++ SP T + + +M + E L +
Sbjct 493 NGSPINEKSDIYSFGLLVWQMFSYA----SPNTIY------SPKEMASMVSDEKLNYRPQ 542
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPT-FENLIPILKTVHEKY 1176
+P P + L+ CW+ RP F +I LK +++ Y
Sbjct 543 IPF--NVPLKFKELITQCWDRNPLNRPKDFSEIIDKLKDINQIY 584
Score = 54.7 bits (130), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 45/183 (25%), Positives = 84/183 (46%), Gaps = 34/183 (19%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV-PL 983
++VAVK + + + E DIL + +I +Y ED + + + MEY+
Sbjct 40 DIVAVKIINK------KFFKRNETDILEKIRLFNIPRYYSHAED--DNYIYIYMEYIEDK 91
Query 984 GSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
LR ++++ + E +++LH +HRD+ N++LD + ++K+ DFG
Sbjct 92 KQLR-------FKESEIISMIADLTETLSFLHKHQILHRDIKPSNIILDKNGVLKLIDFG 144
Query 1044 LAKAVPEGHEYYRVREDGDSPV-----------FWYAPECLKEYKFYYASDVWSFGVTLY 1092
+ + ++DGD+ + APE K ++ SDVWS G T+
Sbjct 145 SSIIDQQ-------QDDGDNICKESSFAITGTHTYMAPEVKKLHRSTKKSDVWSLGCTVL 197
Query 1093 ELL 1095
E++
Sbjct 198 EIV 200
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 51/266 (19%), Positives = 104/266 (39%), Gaps = 33/266 (12%)
Query 635 QELRVVLKVLDPSHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPE----NIMVT 687
E V +K++ +H + + FY ++S + H ++ C++ + +V+
Sbjct 319 NETEVAIKLIKKAHGENVTVCDTFYHEVLIISNLRHPNIVQFIAACIKFDNKEVNHCIVS 378
Query 688 EYVEHGPLDVWLRRERGHVPMA--WKMVVAQQLASALSYLENKNLVHGNVCGRNILL--- 742
E++ G L ++ ER + + ++ + +A + Y + ++H ++ N+LL
Sbjct 379 EWMSGGNLSQFISNERKILEINPHLRVKILLDIAKGMLYSHRQGIIHRDLTSNNVLLNFR 438
Query 743 -----------ARLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIPWLAPECLPGGANS 790
+ K+ D G+ + S++ R I ++APE L G
Sbjct 439 KKKLLNNNSSNNDEQFYDSDEIIAKVCDFGLSSNQSESKKLRGGSIHYMAPENLNGSP-- 496
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP-----QLATLT 845
++ D + FG + ++ F +P SP E + P P + L
Sbjct 497 INEKSDIYSFGLLVWQM-FSYASPNTIYSPKEMASMVSDEKLNYRPQIPFNVPLKFKELI 555
Query 846 SQCLTYEPTQRP-SFRTILRDLTRLQ 870
+QC P RP F I+ L +
Sbjct 556 TQCWDRNPLNRPKDFSEIIDKLKDIN 581
>sp|O64477|Y2913_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At2g19130 OS=Arabidopsis thaliana OX=3702
GN=At2g19130 PE=2 SV=1
Length=828
Score = 84.0 bits (206), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 86/291 (30%), Positives = 132/291 (45%), Gaps = 37/291 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V ++D +AVK L+ Q ++ E+ + T+ H ++++
Sbjct 499 LGGGGFGSVFKGALPDSSD-----IAVKRLEGI--SQGEKQFRTEVVTIGTIQHVNLVRL 551
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLF--AQQICEGMAYLHA 1016
+G C +G K L LV +Y+P GSL +L I L L F A G+AYLH
Sbjct 552 RGFCS-EGSKKL-LVYDYMPNGSLDSHLFLNQVEEKIVLGWKLRFQIALGTARGLAYLHD 609
Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ IH D+ N+LLD+ K+ DFGLAK V G ++ RV + APE +
Sbjct 610 ECRDCIIHCDIKPENILLDSQFCPKVADFGLAKLV--GRDFSRVLTTMRGTRGYLAPEWI 667
Query 1074 KEYKFYYASDVWSFGVTLYELLT---HCDSSQSPPTKFL----ELIGIAQGQMTVL---R 1123
+DV+S+G+ L+EL++ + + S++ +F I G + L R
Sbjct 668 SGVAITAKADVYSYGMMLFELVSGRRNTEQSENEKVRFFPSWAATILTKDGDIRSLVDPR 727
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
L E + R K C C + E S RP ++ IL+ V E
Sbjct 728 LEGDAVDIEEVTRACKVACW-------CIQDEESHRPAMSQVVQILEGVLE 771
Score = 44.3 bits (103), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 53/212 (25%), Positives = 90/212 (42%), Gaps = 36/212 (17%)
Query 640 VLKVLDPSHHDIALAFYETAS-----------LMSQVSHTHLAFVHGVCVRGPENIMVTE 688
V K P DIA+ E S + + H +L + G C G + ++V +
Sbjct 507 VFKGALPDSSDIAVKRLEGISQGEKQFRTEVVTIGTIQHVNLVRLRGFCSEGSKKLLVYD 566
Query 689 YVEHGPLD--VWLRRERGHVPMAWKM--VVAQQLASALSYLENK---NLVHGNVCGRNIL 741
Y+ +G LD ++L + + + WK+ +A A L+YL ++ ++H ++ NIL
Sbjct 567 YMPNGSLDSHLFLNQVEEKIVLGWKLRFQIALGTARGLAYLHDECRDCIIHCDIKPENIL 626
Query 742 LARLGLAEGTSPFI-KLSDPGVGLGALSREERVERI-----PWLAPECLPGGANSLSTAM 795
L S F K++D G+ RV +LAPE + G A ++
Sbjct 627 L--------DSQFCPKVADFGLAKLVGRDFSRVLTTMRGTRGYLAPEWISGVA--ITAKA 676
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
D + +G L E+ QS +EK F+
Sbjct 677 DVYSYGMMLFELVSGRRNTEQSE--NEKVRFF 706
>sp|O23304|BLUS1_ARATH Serine/threonine-protein kinase BLUS1 OS=Arabidopsis
thaliana OX=3702 GN=BLUS1 PE=1 SV=1
Length=487
Score = 82.8 bits (203), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 53/186 (28%), Positives = 93/186 (50%), Gaps = 25/186 (13%)
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
+VA+KA+ D ++E + L H +I+ C ++ L +VM ++ GS
Sbjct 41 VVAIKAIDLDQSRADFDSLRRETKTMSLLSHPNILN--AYCSFTVDRCLWVVMPFMSCGS 98
Query 986 LRDY--------LPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037
L LP + I + F ++ ++YLH Q ++HRD+ A N+L+D+D V
Sbjct 99 LHSIVSSSFPSGLPENCISV-----FLKETLNAISYLHDQGHLHRDIKAGNILVDSDGSV 153
Query 1038 KIGDFGLAKAVPE--------GHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFG 1088
K+ DFG++ ++ E R+ + +P +W APE + + Y + +D+WSFG
Sbjct 154 KLADFGVSASIYEPVTSSSGTTSSSLRLTDIAGTP-YWMAPEVVHSHTGYGFKADIWSFG 212
Query 1089 VTLYEL 1094
+T EL
Sbjct 213 ITALEL 218
Score = 36.6 bits (83), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 44/181 (24%), Positives = 69/181 (38%), Gaps = 38/181 (21%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS---- 768
V ++ +A+SYL ++ +H ++ NIL+ G +KL+D GV
Sbjct 118 VFLKETLNAISYLHDQGHLHRDIKAGNILVDSDG-------SVKLADFGVSASIYEPVTS 170
Query 769 ---------REERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
R + P W+APE + A D W FG T LE+ G PL
Sbjct 171 SSGTTSSSLRLTDIAGTPYWMAPEVVHSHTGYGFKA-DIWSFGITALELAH-GRPPLSHL 228
Query 819 SP--------SEKEHFYQRQHRLPEPS-------CPQLATLTSQCLTYEPTQRPSFRTIL 863
P +++ HF + S + CL +PT+RPS +L
Sbjct 229 PPLKSLLMKITKRFHFSDYEINTSGSSKKGNKKFSKAFREMVGLCLEQDPTKRPSAEKLL 288
Query 864 R 864
+
Sbjct 289 K 289
>sp|Q86CS2|ATG1_DICDI Serine/threonine-protein kinase atg1 OS=Dictyostelium
discoideum OX=44689 GN=atg1 PE=3 SV=1
Length=668
Score = 83.6 bits (205), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 58/203 (29%), Positives = 97/203 (48%), Gaps = 17/203 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK----ADCGPQHRSGWKQEIDILRTLYHEH 958
+G G F +V Y + T E A+K + AD + EI IL+ L H +
Sbjct 13 IGWGAFAQV----YKGFSIKTNEPFAIKVVDVCRLADKNSKLTENLNYEIRILKELSHTN 68
Query 959 IIK-YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016
I++ Y E+ + ++ME G Y+ H + + L F +Q+ G+ +L
Sbjct 69 IVRLYDVLNEETDPTFIYMIMECCEGGDFSKYIRTHKKLTEEKALYFMKQLANGLKFLRQ 128
Query 1017 QHYIHRDLAARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ +HRDL +N+LL +D ++KIGDFG AK + + + + + + APE L
Sbjct 129 KQIVHRDLKPQNLLLSDDSEHPILKIGDFGFAKFI----DPFSLSDTFCGSPLYMAPEIL 184
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
+ +D+WS G+ LYE+L
Sbjct 185 HRKNYTVKADLWSVGIILYEMLV 207
Score = 41.2 bits (95), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 48/205 (23%), Positives = 86/205 (42%), Gaps = 15/205 (7%)
Query 661 LMSQVSHTHLAFVHGVCVR--GPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQ 717
++ ++SHT++ ++ V P I M+ E E G ++R + + + +Q
Sbjct 60 ILKELSHTNIVRLYDVLNEETDPTFIYMIMECCEGGDFSKYIRTHK-KLTEEKALYFMKQ 118
Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVER 775
LA+ L +L K +VH ++ +N+LL+ + P +K+ D G + S +
Sbjct 119 LANGLKFLRQKQIVHRDLKPQNLLLS----DDSEHPILKIGDFGFAKFIDPFSLSDTFCG 174
Query 776 IP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRL 833
P ++APE L + + D W G L E+ GE S S P ++ +L
Sbjct 175 SPLYMAPEIL--HRKNYTVKADLWSVGIILYEMLV-GEPAYNSGSVPDLLNQLQNKKIKL 231
Query 834 PEPSCPQLATLTSQCLTYEPTQRPS 858
P L L + +R S
Sbjct 232 PSHISSDCQNLIYSLLQIDVEKRIS 256
>sp|C0LGH3|Y5614_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g56140 OS=Arabidopsis thaliana OX=3702
GN=At1g56140 PE=2 SV=2
Length=1033
Score = 84.0 bits (206), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 69/208 (33%), Positives = 98/208 (47%), Gaps = 32/208 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG V NDG VAVK L Q + + EI + + H +++K
Sbjct 699 LGEGGFGPV---YKGKLNDG--REVAVKLLSVGS-RQGKGQFVAEIVAISAVQHRNLVKL 752
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLR-----------DYLPRHSIGLAQLLLFAQQICEGM 1011
GCC +GE L LV EY+P GSL D+ R+ I L + G+
Sbjct 753 YGCCY-EGEHRL-LVYEYLPNGSLDQALFGEKTLHLDWSTRYEICLG--------VARGL 802
Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
YLH + +HRD+ A N+LLD+ + K+ DFGLAK + + R G + +
Sbjct 803 VYLHEEARLRIVHRDVKASNILLDSKLVPKVSDFGLAKLYDDKKTHISTRVAG--TIGYL 860
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLT 1096
APE +DV++FGV EL++
Sbjct 861 APEYAMRGHLTEKTDVYAFGVVALELVS 888
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 63/236 (27%), Positives = 97/236 (41%), Gaps = 44/236 (19%)
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
G G +GK++D GR+ V +K+L F +S V H +L
Sbjct 703 GFGPVYKGKLND------GRE------VAVKLLSVGSRQGKGQFVAEIVAISAVQHRNLV 750
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENK-- 728
++G C G ++V EY+ +G LD L E+ H+ + + + +A L YL +
Sbjct 751 KLYGCCYEGEHRLLVYEYLPNGSLDQALFGEKTLHLDWSTRYEICLGVARGLVYLHEEAR 810
Query 729 -NLVHGNVCGRNILLARLGLAEGTSPFI-KLSDPGVGLGALSREERVE-------RIPWL 779
+VH +V NILL S + K+SD GL L +++ I +L
Sbjct 811 LRIVHRDVKASNILL--------DSKLVPKVSD--FGLAKLYDDKKTHISTRVAGTIGYL 860
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
APE G L+ D + FG LE L S P+ E+ + L E
Sbjct 861 APEYAMRG--HLTEKTDVYAFGVVALE--------LVSGRPNSDENLEDEKRYLLE 906
>sp|Q9LUT0|CARK1_ARATH Receptor-like cytoplasmic kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=CARK1 PE=1 SV=1
Length=364
Score = 81.6 bits (200), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 87/322 (27%), Positives = 138/322 (43%), Gaps = 38/322 (12%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRD-------LGEGHFGKVSLYCYDPTNDGT 923
P NL V+ + P S A+ P L+ I D +GEG +G+V +
Sbjct 41 PKNLP-VIQMQPISVAAIPA----DELRDITDNYGSKSLIGEGSYGRVFYGILK-----S 90
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
G+ A+K L D Q + ++ ++ L E+++ G C D + L EY P
Sbjct 91 GKAAAIKKL--DSSKQPDQEFLAQVSMVSRLRQENVVALLGYCVDGPLRVL--AYEYAPN 146
Query 984 GSLRDYL----------PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVL 1030
GSL D L P + Q + A G+ YLH + H IHRD+ + NVL
Sbjct 147 GSLHDILHGRKGVKGAQPGPVLSWHQRVKIAVGAARGLEYLHEKANPHVIHRDIKSSNVL 206
Query 1031 LDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
L +D + KI DF L+ P+ + R G ++APE SDV+SFGV
Sbjct 207 LFDDDVAKIADFDLSNQAPDMAARLHSTRVLGT--FGYHAPEYAMTGTLSTKSDVYSFGV 264
Query 1090 TLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148
L ELLT + P ++ A +++ ++ + ++ P K ++ +
Sbjct 265 VLLELLTGRKPVDHTLPRGQQSVVTWATPKLSEDKVKQCVDARLNGEYPPKAVAKLAAVA 324
Query 1149 KNCWETEASFRPTFENLIPILK 1170
C + EA FRP ++ L+
Sbjct 325 ALCVQYEADFRPNMSIVVKALQ 346
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 49/178 (28%), Positives = 82/178 (46%), Gaps = 17/178 (10%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRE--RGHVP---M 708
F S++S++ ++ + G CV GP ++ EY +G L D+ R+ +G P +
Sbjct 109 FLAQVSMVSRLRQENVVALLGYCVDGPLRVLAYEYAPNGSLHDILHGRKGVKGAQPGPVL 168
Query 709 AW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+W ++ +A A L YL N +++H ++ N+LL +A+ LS+
Sbjct 169 SWHQRVKIAVGAARGLEYLHEKANPHVIHRDIKSSNVLLFDDDVAKIAD--FDLSNQAPD 226
Query 764 LGALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+ A RV + APE G +LST D + FG LLE+ G P+ P
Sbjct 227 MAARLHSTRVLGTFGYHAPEYAMTG--TLSTKSDVYSFGVVLLEL-LTGRKPVDHTLP 281
>sp|O88831|KKCC2_RAT Calcium/calmodulin-dependent protein kinase
kinase 2 OS=Rattus norvegicus OX=10116 GN=Camkk2 PE=1 SV=1
Length=587
Score = 83.2 bits (204), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 52/150 (35%), Positives = 77/150 (51%), Gaps = 6/150 (4%)
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ 1005
QEI IL+ L H +++K +D E L +V E V G + + + Q + Q
Sbjct 234 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQ 293
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
+ +G+ YLH Q IHRD+ N+L+ D +KI DFG++ +G + G +P
Sbjct 294 DLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF-KGSDALLSNTVG-TPA 351
Query 1066 FWYAPECLKEYKFYY---ASDVWSFGVTLY 1092
F APE L E + + A DVW+ GVTLY
Sbjct 352 FM-APESLSETRKIFSGKALDVWAMGVTLY 380
>sp|O64771|Y1148_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61480 OS=Arabidopsis thaliana OX=3702
GN=At1g61480 PE=2 SV=2
Length=809
Score = 84.0 bits (206), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 68/201 (34%), Positives = 99/201 (49%), Gaps = 16/201 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V G+ +AVK L + G Q + + EI ++ L H+++++
Sbjct 502 LGQGGFGSVY-----KGKLQDGKEIAVKRLSSSSG-QGKEEFMNEIVLISKLQHKNLVRI 555
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017
GCC +GE+ L LV E++ SL +L R I + + I G+ YLH
Sbjct 556 LGCC-IEGEERL-LVYEFLLNKSLDTFLFDSRKRLEIDWPKRFNIIEGIARGLHYLHRDS 613
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
IHRDL N+LLD KI DFGLA+ + +G EY + + APE
Sbjct 614 CLRVIHRDLKVSNILLDEKMNPKISDFGLAR-MYQGTEYQDNTRRVAGTLGYMAPEYAWT 672
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
F SD++SFGV L E++T
Sbjct 673 GMFSEKSDIYSFGVILLEIIT 693
>sp|O61661|CHK1_DROME Serine/threonine-protein kinase grp OS=Drosophila
melanogaster OX=7227 GN=grp PE=1 SV=2
Length=512
Score = 82.8 bits (203), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 64/197 (32%), Positives = 100/197 (51%), Gaps = 14/197 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG +G+V L N TGE VA+K + P + ++E+ I + L +HI+++
Sbjct 28 LGEGAYGEVKLLI----NRQTGEAVAMKMVDLKKHPDAANSVRKEVCIQKMLQDKHILRF 83
Query 963 KGCCEDQGEKSLQLV-MEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQHY 1019
G + + S++ + +EY G L D + +G+ Q + Q+ G+ YLH +
Sbjct 84 FG---KRSQGSVEYIFLEYAAGGELFDRI-EPDVGMPQHEAQRYFTQLLSGLNYLHQRGI 139
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N+LLD VKI DFG+A +G E + G P + APE L++
Sbjct 140 AHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLP--YVAPEVLQKAYH 197
Query 1079 YYASDVWSFGVTLYELL 1095
+D+WS GV L +L
Sbjct 198 AQPADLWSCGVILVTML 214
Score = 36.6 bits (83), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 47/200 (24%), Positives = 81/200 (41%), Gaps = 24/200 (12%)
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
E L+ R G+ V +K++D H D A + + + + H+ G +G
Sbjct 35 EVKLLINRQTGEA--VAMKMVDLKKHPDAANSVRKEVCIQKMLQDKHILRFFGKRSQGSV 92
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+ EY G L + + G +P QL S L+YL + + H ++ N+LL
Sbjct 93 EYIFLEYAAGGELFDRIEPDVG-MPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENLLL 151
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSR--------EERVERIPWLAPECLPGGANSLSTA 794
+K+SD G+ + R ++R +P++APE L + +
Sbjct 152 DE-------HDNVKISD--FGMATMFRCKGKERLLDKRCGTLPYVAPEVLQKAYH--AQP 200
Query 795 MDKWGFGATLLEICFDGEAP 814
D W G L+ + GE P
Sbjct 201 ADLWSCGVILVTM-LAGELP 219
>sp|Q8INB9|AKT1_DROME RAC serine/threonine-protein kinase OS=Drosophila
melanogaster OX=7227 GN=Akt PE=1 SV=3
Length=611
Score = 83.6 bits (205), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 64/199 (32%), Positives = 95/199 (48%), Gaps = 12/199 (6%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHE 957
++ LG+G FGKV L C + T ++ A+K LK + Q + E +L++ H
Sbjct 269 LKVLGKGTFGKVIL-CRE---KATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHP 324
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA-QLLLFAQQICEGMAYLHA 1016
+I K Q L VM+YV G L +L I + + +I + YLH+
Sbjct 325 FLISLKYSF--QTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHS 382
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
Q I+RDL N+LLD D +K+ DFGL K E Y R + + APE L +
Sbjct 383 QGIIYRDLKLENLLLDKDGHIKVADFGLCK---EDITYGRTTKTFCGTPEYLAPEVLDDN 439
Query 1077 KFYYASDVWSFGVTLYELL 1095
+ A D W GV +YE++
Sbjct 440 DYGQAVDWWGTGVVMYEMI 458
Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 39/139 (28%), Positives = 62/139 (45%), Gaps = 17/139 (12%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
V +YV G L L ER + A+ + SAL YL ++ +++ ++ N+LL +
Sbjct 341 FVMQYVNGGELFWHLSHERIFTEDRTRFYGAE-IISALGYLHSQGIIYRDLKLENLLLDK 399
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGF 800
G IK++D G+ ++ + +LAPE L N A+D WG
Sbjct 400 DG-------HIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDD--NDYGQAVDWWGT 450
Query 801 GATLLE-ICFDGEAPLQSR 818
G + E IC G P +R
Sbjct 451 GVVMYEMIC--GRLPFYNR 467
>sp|Q621J7|ZYG1_CAEBR Probable serine/threonine-protein kinase
zyg-1 OS=Caenorhabditis briggsae OX=6238 GN=zyg-1 PE=3 SV=1
Length=709
Score = 83.6 bits (205), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 67/217 (31%), Positives = 109/217 (50%), Gaps = 26/217 (12%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+ ++ +G+G FG V Y N GE VA+K + + Q R K+EI ++ L H
Sbjct 13 FQNLQQIGQGGFGVV--YSAQREN---GEKVAIKKI-GNAASQTR--IKEEIKTMKLLRH 64
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLH 1015
+I+++ + GE LVME GSL DY+ + + + + +Q+ + Y+H
Sbjct 65 RNIVQFYETFFENGE--TYLVMELCEGGSLMDYVKQKGPLDDSTAVHILRQLIAAVKYIH 122
Query 1016 AQHYIHRDLAARNVLLDNDR----LVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAP 1070
++ +HRDL+A NV + + VK+GDFGLA + + G V G + AP
Sbjct 123 DENILHRDLSAGNVFIKDATKSTITVKLGDFGLATNLGQHGTACTIVGTPG-----FIAP 177
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ + + A+DV+S G LY +LT +PPTK
Sbjct 178 QVFGQ-NYDQAADVYSLGAVLYTMLTK----HTPPTK 209
>sp|Q9LP51|CIPKI_ARATH CBL-interacting serine/threonine-protein
kinase 18 OS=Arabidopsis thaliana OX=3702 GN=CIPK18 PE=1 SV=1
Length=520
Score = 83.2 bits (204), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 77/234 (33%), Positives = 114/234 (49%), Gaps = 33/234 (14%)
Query 879 TVNPDSPAS-----DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933
++P SP S + + K L K+ LG G F KV Y N +G+ VA+K +
Sbjct 53 NISPQSPRSPRSPRNNILMGKYELGKL--LGHGTFAKV----YLAQNIKSGDKVAIKVI- 105
Query 934 ADCGPQHRSGW----KQEIDILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRD 988
D +SG K+EI ILR + H +I+ E KS + VMEYV G L +
Sbjct 106 -DKEKIMKSGLVAHIKREISILRRVRHPYIVH---LFEVMATKSKIYFVMEYVGGGELFN 161
Query 989 YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ + + + QQ+ +++ H + HRDL N+LLDN +K+ DFGL+ AV
Sbjct 162 TVAKGRLPEETARRYFQQLISSVSFCHGRGVYHRDLKPENLLLDNKGNLKVSDFGLS-AV 220
Query 1049 PEGHEYYRVREDGDSPVF-----WYAPECLKEYKFYYA-SDVWSFGVTLYELLT 1096
E ++R+DG F + APE L + A +DVWS GV L+ L+
Sbjct 221 AE-----QLRQDGLCHTFCGTPAYIAPEVLTRKGYDAAKADVWSCGVILFVLMA 269
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 53/240 (22%), Positives = 97/240 (40%), Gaps = 25/240 (10%)
Query 638 RVVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+V +KV+D + S++ +V H ++ + V + V EYV G
Sbjct 99 KVAIKVIDKEKIMKSGLVAHIKREISILRRVRHPYIVHLFEVMATKSKIYFVMEYVGGGE 158
Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
L + +G +P QQL S++S+ + + H ++ N+LL G
Sbjct 159 L--FNTVAKGRLPEETARRYFQQLISSVSFCHGRGVYHRDLKPENLLLDNKG-------N 209
Query 755 IKLSDPGVGLGALSREERVERI--------PWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+K+SD GL A++ + R + + ++APE L + A D W G L
Sbjct 210 LKVSD--FGLSAVAEQLRQDGLCHTFCGTPAYIAPEVLTRKGYDAAKA-DVWSCGVILF- 265
Query 807 ICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ G P ++ + Y+ + R P L L ++ L P R + I+++
Sbjct 266 VLMAGHIPFYDKNIMVMYKKIYKGEFRCPRWFSSDLVRLLTRLLDTNPDTRITIPEIMKN 325
>sp|Q8W1D5|CIPKP_ARATH CBL-interacting serine/threonine-protein
kinase 25 OS=Arabidopsis thaliana OX=3702 GN=CIPK25 PE=2 SV=1
Length=488
Score = 82.8 bits (203), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 66/207 (32%), Positives = 105/207 (51%), Gaps = 26/207 (13%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYH 956
R LG+G FGKV Y TGE VA+K + D R G K+EI I+R + H
Sbjct 47 RLLGKGTFGKV----YYGKEITTGESVAIKIINKD--QVKREGMMEQIKREISIMRLVRH 100
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016
+I++ K + + + +MEYV G L + + + + QQ+ + + H+
Sbjct 101 PNIVELKEVMATKTK--IFFIMEYVKGGELFSKIVKGKLKEDSARKYFQQLISAVDFCHS 158
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG------DSPVFWYAP 1070
+ HRDL N+L+D + +K+ DFGL+ A+PE ++ +DG +P + AP
Sbjct 159 RGVSHRDLKPENLLVDENGDLKVSDFGLS-ALPE-----QILQDGLLHTQCGTPAY-VAP 211
Query 1071 ECLKEYKFYYAS-DVWSFGVTLYELLT 1096
E L++ + A D+WS G+ LY LL
Sbjct 212 EVLRKKGYDGAKGDIWSCGIILYVLLA 238
Score = 38.1 bits (87), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 48/214 (22%), Positives = 88/214 (41%), Gaps = 22/214 (10%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M V H ++ + V + + EYV+ G L + + +G + QQL
Sbjct 93 SIMRLVRHPNIVELKEVMATKTKIFFIMEYVKGGEL--FSKIVKGKLKEDSARKYFQQLI 150
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776
SA+ + ++ + H ++ N+L+ G +K+SD GL AL + + +
Sbjct 151 SAVDFCHSRGVSHRDLKPENLLVDENGD-------LKVSD--FGLSALPEQILQDGLLHT 201
Query 777 -----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQ 830
++APE L + D W G +L + G P Q + + ++ +
Sbjct 202 QCGTPAYVAPEVLRKKGYDGAKG-DIWSCG-IILYVLLAGFLPFQDENLMKMYRKIFKSE 259
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
P P+ L S+ L +P +R S I+R
Sbjct 260 FEYPPWFSPESKRLISKLLVVDPNKRISIPAIMR 293
>sp|Q8BPM2|M4K5_MOUSE Mitogen-activated protein kinase kinase
kinase kinase 5 OS=Mus musculus OX=10090 GN=Map4k5 PE=1 SV=2
Length=847
Score = 84.0 bits (206), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 68/224 (30%), Positives = 105/224 (47%), Gaps = 25/224 (11%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
AD+L NP H L ++ +G G +G V Y N TGE+ AVK +K
Sbjct 9 ADILRRNPQ---------HDYEL--VQRVGSGTYGDV----YKARNVHTGELAAVKIIKL 53
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRH 993
+ G S +QEI +++ H +I+ Y G + L + MEY GSL+D Y
Sbjct 54 EPGDDF-SLIQQEIFMVKECKHCNIVAYFGSY--LSREKLWICMEYCGGGSLQDIYHVTG 110
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ Q+ ++ +G+AYLH + +HRD+ N+LL + VK+ DFG+A +
Sbjct 111 PLSEMQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITAT-- 168
Query 1054 YYRVREDGDSPVFWYAPECL---KEYKFYYASDVWSFGVTLYEL 1094
R+ +W APE K + D+W+ G+T EL
Sbjct 169 -IAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIEL 211
Score = 40.0 bits (92), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 49/190 (26%), Positives = 75/190 (39%), Gaps = 26/190 (14%)
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSRE 770
V ++ L+YL K +H ++ G NILL G +KL+D GV +++
Sbjct 120 VCRETLQGLAYLHTKGKMHRDIKGANILLTDHG-------DVKLADFGVAAKITATIAKR 172
Query 771 ERVERIP-WLAPECLP----GGANSLSTAMDKWGFGATLLEI------CFDGEAPLQSRS 819
+ P W+APE GG N L D W G T +E+ FD P+++
Sbjct 173 KSFIGTPYWMAPEVAAVEKNGGYNQLC---DIWAVGITAIELGELQPPMFDLH-PMRALF 228
Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
K +F + + LT P +RP+ +L QP L+ L
Sbjct 229 LMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVGQP-GLSRALA 287
Query 880 VNPDSPASDP 889
V S+P
Sbjct 288 VELLDKVSNP 297
>sp|Q9M342|WAKLP_ARATH Wall-associated receptor kinase-like 15
OS=Arabidopsis thaliana OX=3702 GN=WAKL15 PE=2 SV=2
Length=639
Score = 83.6 bits (205), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 79/258 (31%), Positives = 118/258 (46%), Gaps = 43/258 (17%)
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917
S R + R+L + L + T A+D F K L LG G FG+V
Sbjct 322 SVRKLHRNLLSINSTGLDRIFTGKEIVKATDN--FAKSNL-----LGFGGFGEVF----- 369
Query 918 PTNDGTGEMVAVKALKADCGPQHRSGWK--QEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
N G VAVK K +S ++ E+ IL + H++++K GCC + +
Sbjct 370 KGNLDDGTTVAVKRAKLG---NEKSIYQIVNEVQILCQVSHKNLVKLLGCCIEL--EMPV 424
Query 976 LVMEYVPLGSL--------------RDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH--- 1018
LV E+VP G+L D+LP L + L+ A Q +G+ YLH+
Sbjct 425 LVYEFVPNGTLFEHIYGGGGGGGGLYDHLP-----LRRRLMIAHQTAQGLDYLHSSSSPP 479
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRD+ + N+LLD + VK+ DFGL++ + G + + PE ++
Sbjct 480 IYHRDVKSSNILLDENLDVKVADFGLSRLGVSDVSHVTTCAQG--TLGYLDPEYYLNFQL 537
Query 1079 YYASDVWSFGVTLYELLT 1096
SDV+SFGV L+ELLT
Sbjct 538 TDKSDVYSFGVVLFELLT 555
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 55/254 (22%), Positives = 102/254 (40%), Gaps = 36/254 (14%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
AS R L+ + LS + I + + T L G G+ +G +DD +
Sbjct 321 ASVRKLHRNLLSINSTGLDRIFTGKEIVKATDNFAKSNLLGFGGFGEVFKGNLDDGTTVA 380
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
R + + + ++++ ++ QVSH +L + G C+ ++V E
Sbjct 381 VKRAKLGNEKSIYQIVNE------------VQILCQVSHKNLVKLLGCCIELEMPVLVYE 428
Query 689 YVEHGPLDVWLRRER-------GHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGR 738
+V +G L + H+P+ ++++A Q A L YL + + + H +V
Sbjct 429 FVPNGTLFEHIYGGGGGGGGLYDHLPLRRRLMIAHQTAQGLDYLHSSSSPPIYHRDVKSS 488
Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLST 793
NILL + +K++D G+ +S V + +L PE L+
Sbjct 489 NILLDE-------NLDVKVADFGLSRLGVSDVSHVTTCAQGTLGYLDPEYYLNF--QLTD 539
Query 794 AMDKWGFGATLLEI 807
D + FG L E+
Sbjct 540 KSDVYSFGVVLFEL 553
>sp|Q9HFF4|PPK1_SCHPO Serine/threonine-protein kinase ppk1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=ppk1 PE=1 SV=2
Length=1023
Score = 84.0 bits (206), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 73/220 (33%), Positives = 103/220 (47%), Gaps = 33/220 (15%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGT----GEMVAVK---ALKADCGPQHRSGWKQEIDILRT 953
R +G G FGKV L P + T V +K + K +C S +E+ IL+
Sbjct 496 RTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIVLSTKQNC---QTSRLMREVAILKG 552
Query 954 L--YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICEG 1010
L H HI+KY + + +V++YV G L DY L R + + Q+ G
Sbjct 553 LGNNHPHIVKYLDFVKTKHH--FGIVLDYVNGGELFDYILARRRLEDSVACRLFAQLISG 610
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH-----EYYRVREDGD--- 1062
+AYLH++ +HRDL N+LLD +R + I DFG A GH E+ E D
Sbjct 611 VAYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTF--GHFNTLSEHSLPTEKPDLFS 668
Query 1063 ----SPVFWYAPECLKEYKFYYA---SDVWSFGVTLYELL 1095
SP + APE + YA +D+WS GV LY +L
Sbjct 669 TSCGSPC-YAAPELVNCKSGMYAGTQADIWSCGVILYAML 707
>sp|Q01919|KIN4_YEAST Serine/threonine-protein kinase KIN4 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=KIN4 PE=1 SV=1
Length=800
Score = 83.6 bits (205), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 67/201 (33%), Positives = 99/201 (49%), Gaps = 14/201 (7%)
Query 903 LGEGHFGKVSL-YCYDPTNDGTGEMVAVKALKADC---GPQHRSGWKQEIDILRTLYHEH 958
LGEG FGKV L + +++ + VA+K ++ D +EI+ L+ L H +
Sbjct 52 LGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPN 111
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHA 1016
II + Q K + +V+E+V G Y+ R + LFAQ I G+ Y+H
Sbjct 112 IIYLEEVL--QNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLIS-GVNYMHY 168
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ +HRDL N+LLD + I DFG E +E ++ SP + APE +
Sbjct 169 KGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNEL--MKTSCGSPCYA-APELVVST 225
Query 1077 KFYYA--SDVWSFGVTLYELL 1095
K Y A +DVWS GV LY +L
Sbjct 226 KAYEARKADVWSCGVILYAML 246
>sp|Q7RZD3|STE20_NEUCR Serine/threonine-protein kinase ste20 OS=Neurospora
crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71
/ DSM 1257 / FGSC 987) OX=367110 GN=stk-4 PE=3 SV=1
Length=954
Score = 84.0 bits (206), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 55/208 (26%), Positives = 101/208 (49%), Gaps = 14/208 (7%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP ++ + K +G+G G V Y G+ +VA+K + + P+ + E
Sbjct 669 DPREIYRGFTK----IGQGASGGV----YTGHERGSNRLVAIKQMNLEQQPK-KDLIINE 719
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +++ H +I+ + GE L +VMEY+ GSL D + + + Q+ ++
Sbjct 720 ILVMKESSHPNIVNFIDSYLCAGE--LWVVMEYMEGGSLTDVVTFNIMTEGQIASVCRET 777
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
G+ +LH++ IHRD+ + N+LL + +K+ DFG + E + R G +W
Sbjct 778 LRGLQHLHSKGVIHRDIKSDNILLSMEGNIKLTDFGFCATINEA-QSKRTTMVGTP--YW 834
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095
APE + ++ D+WS G+ E++
Sbjct 835 MAPEVVTRKEYGRKVDIWSLGIMAIEMI 862
Score = 43.1 bits (100), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 52/206 (25%), Positives = 85/206 (41%), Gaps = 38/206 (18%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA-FVHGVCVRGPENIMVTE 688
G +RG V +K ++ +M + SH ++ F+ G E +V E
Sbjct 691 GHERGSNRLVAIKQMNLEQQPKKDLIINEILVMKESSHPNIVNFIDSYLCAG-ELWVVME 749
Query 689 YVEHGPL-DVWLRRERGHVPMAWKMVVAQQLAS-------ALSYLENKNLVHGNVCGRNI 740
Y+E G L DV + + ++ Q+AS L +L +K ++H ++ NI
Sbjct 750 YMEGGSLTDV----------VTFNIMTEGQIASVCRETLRGLQHLHSKGVIHRDIKSDNI 799
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTA 794
LL+ G IKL+D G A E + +R W+APE +
Sbjct 800 LLSMEG-------NIKLTD--FGFCATINEAQSKRTTMVGTPYWMAPEVV--TRKEYGRK 848
Query 795 MDKWGFGATLLEICFDGEAPLQSRSP 820
+D W G +E+ +GE P + SP
Sbjct 849 VDIWSLGIMAIEM-IEGEPPYLTESP 873
>sp|O04533|LRK52_ARATH Putative L-type lectin-domain containing
receptor kinase V.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK52
PE=3 SV=1
Length=656
Score = 83.2 bits (204), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 66/202 (33%), Positives = 99/202 (49%), Gaps = 23/202 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---EIDILRTLYHEHI 959
LG+G FGKV + + +AVK + D R G ++ EI + L H +
Sbjct 340 LGKGGFGKV----FKGILPLSSIPIAVKKISHDS----RQGMREFLAEIATIGRLRHPDL 391
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH- 1015
++ G C +GE L LV +++P GSL +L P + +Q + + G+ YLH
Sbjct 392 VRLLGYCRRKGE--LYLVYDFMPKGSLDKFLYNQPNQILDWSQRFNIIKDVASGLCYLHQ 449
Query 1016 --AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072
Q IHRD+ N+LLD + K+GDFGLAK G + G F Y +PE
Sbjct 450 QWVQVIIHRDIKPANILLDENMNAKLGDFGLAKLCDHGIDSQTSNVAG---TFGYISPEL 506
Query 1073 LKEYKFYYASDVWSFGVTLYEL 1094
+ K +SDV++FGV + E+
Sbjct 507 SRTGKSSTSSDVFAFGVFMLEI 528
>sp|Q2TBL8|CDK10_BOVIN Cyclin-dependent kinase 10 OS=Bos taurus
OX=9913 GN=CDK10 PE=2 SV=1
Length=361
Score = 81.3 bits (199), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 69/214 (32%), Positives = 101/214 (47%), Gaps = 26/214 (12%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDI 950
+ +K+ +GEG +G V Y + T E+VA+K ++ D + + G +EI +
Sbjct 35 KEFEKLNRIGEGTYGIV----YRARDTHTDEIVALKKVRMD---KEKDGVPISSLREITL 87
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQIC 1008
L L H +I++ K +S+ LVM Y L SL + +P AQ+ Q+
Sbjct 88 LLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPT-PFSEAQVKCIVLQVL 146
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP---V 1065
G+ YLH IHRDL N+L+ + VK DFGLA+A Y + +P
Sbjct 147 RGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARA-------YGIPVKPMTPKVVT 199
Query 1066 FWY-APECLKEYKFYYAS-DVWSFGVTLYELLTH 1097
WY APE L S D+W+ G L ELL H
Sbjct 200 LWYRAPELLLGTTTQTTSIDMWAVGCILAELLAH 233
>sp|Q2VWQ3|STE20_TALMA Serine/threonine-protein kinase pakA OS=Talaromyces
marneffei OX=37727 GN=pakA PE=3 SV=1
Length=642
Score = 83.2 bits (204), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 57/208 (27%), Positives = 103/208 (50%), Gaps = 14/208 (7%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DPT K+Y + +G+G G V Y+ TN T + VA+K + D P+ + E
Sbjct 356 DPT---KKYYN-LNKIGQGASGGV-FTAYE-TN--TNKCVAIKQMNLDLQPK-KDLIINE 406
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +++ H++I+ + + L +VMEY+ GSL D + + + Q+ ++
Sbjct 407 ILVMKDSKHKNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMSEGQIAAVCRET 464
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
G+ +LH++ IHRD+ + N+LL D +K+ DFG + ++ R +W
Sbjct 465 LSGLQHLHSKGVIHRDIKSDNILLSMDGEIKLTDFGFCAQI---NDSQNKRNTMVGTPYW 521
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095
APE + ++ D+WS G+ E++
Sbjct 522 MAPEVVTRKEYGRKVDIWSLGIMAIEMI 549
Score = 39.3 bits (90), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 43/165 (26%), Positives = 69/165 (42%), Gaps = 18/165 (11%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719
+M H ++ + G + +V EY+E G L DV +A V ++
Sbjct 409 VMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVVTFNIMSEGQIA---AVCRETL 465
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERVER 775
S L +L +K ++H ++ NILL+ G IKL+D G + R V
Sbjct 466 SGLQHLHSKGVIHRDIKSDNILLSMDGE-------IKLTDFGFCAQINDSQNKRNTMVGT 518
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
W+APE + +D W G +E+ +GE P + SP
Sbjct 519 PYWMAPEVV--TRKEYGRKVDIWSLGIMAIEM-IEGEPPYLTESP 560
>sp|Q8GYA4|CRK10_ARATH Cysteine-rich receptor-like protein kinase
10 OS=Arabidopsis thaliana OX=3702 GN=CRK10 PE=1 SV=3
Length=669
Score = 83.2 bits (204), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 84/284 (30%), Positives = 132/284 (46%), Gaps = 31/284 (11%)
Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G FG+V Y T +DGT VAVK L G Q +K E+ ++ L H ++++
Sbjct 354 IGQGGFGEV----YKGTLSDGT--EVAVKRLSKSSG-QGEVEFKNEVVLVAKLQHRNLVR 406
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
G C D E+ L V EYVP SL +L + + + + G+ YLH
Sbjct 407 LLGFCLDGEERVL--VYEYVPNKSLDYFLFDPAKKGQLDWTRRYKIIGGVARGILYLHQD 464
Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF----WYAP 1070
IHRDL A N+LLD D KI DFG+A+ E+ S + + +P
Sbjct 465 SRLTIIHRDLKASNILLDADMNPKIADFGMARIFGLDQT-----EENTSRIVGTYGYMSP 519
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL-ELIGIAQGQMTVLRLTELLE 1129
E ++ SDV+SFGV + E+++ +S T +L+ A G + R EL++
Sbjct 520 EYAMHGQYSMKSDVYSFGVLVLEIISGKKNSSFYQTDGAHDLVSYAWGLWSNGRPLELVD 579
Query 1130 RG--ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
E R + C H+ C + + + RPT ++ +L +
Sbjct 580 PAIVENCQRNEVVRC--VHIGLLCVQEDPAERPTLSTIVLMLTS 621
Score = 51.2 bits (121), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 64/270 (24%), Positives = 109/270 (40%), Gaps = 63/270 (23%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K L S + F L++++ H +L + G C+ G E ++V EYV + LD +
Sbjct 373 VAVKRLSKSSGQGEVEFKNEVVLVAKLQHRNLVRLLGFCLDGEERVLVYEYVPNKSLDYF 432
Query 699 LRR--ERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSP 753
L ++G + + + +A + YL + ++H ++ NIL L +P
Sbjct 433 LFDPAKKGQLDWTRRYKIIGGVARGILYLHQDSRLTIIHRDLKASNIL-----LDADMNP 487
Query 754 FIKLSDPGVG--LGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
K++D G+ G EE RI +++PE G S+ + D + FG +LEI
Sbjct 488 --KIADFGMARIFGLDQTEENTSRIVGTYGYMSPEYAMHGQYSMKS--DVYSFGVLVLEI 543
Query 808 CFDGEAPLQSRSPSEKEHFYQ------------------RQHRLPEPS------------ 837
S + FYQ R L +P+
Sbjct 544 I----------SGKKNSSFYQTDGAHDLVSYAWGLWSNGRPLELVDPAIVENCQRNEVVR 593
Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
C + L C+ +P +RP+ TI+ LT
Sbjct 594 CVHIGLL---CVQEDPAERPTLSTIVLMLT 620
>sp|Q15831|STK11_HUMAN Serine/threonine-protein kinase STK11 OS=Homo
sapiens OX=9606 GN=STK11 PE=1 SV=1
Length=433
Score = 82.0 bits (201), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 95/198 (48%), Gaps = 6/198 (3%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG +GKV D + +K K P + K+EI +LR L H+++I+
Sbjct 55 LGEGSYGKVK-EVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQL 113
Query 963 KGCCEDQGEKSLQLVMEYVPLG--SLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
++ ++ + +VMEY G + D +P + Q + Q+ +G+ YLH+Q +
Sbjct 114 VDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIV 173
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
H+D+ N+LL +KI D G+A+A+ R SP F PE +
Sbjct 174 HKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQ-PPEIANGLDTFS 232
Query 1080 -YASDVWSFGVTLYELLT 1096
+ D+WS GVTLY + T
Sbjct 233 GFKVDIWSAGVTLYNITT 250
Score = 43.5 bits (101), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 48/188 (26%), Positives = 73/188 (39%), Gaps = 21/188 (11%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL-- 742
MV EY G ++ P+ QL L YL ++ +VH ++ N+LL
Sbjct 127 MVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTT 186
Query 743 ------ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLST-AM 795
+ LG+AE PF G+ P P + G ++ S +
Sbjct 187 GGTLKISDLGVAEALHPFAADDTCRTSQGS----------PAFQPPEIANGLDTFSGFKV 236
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854
D W G TL I G P + + + E+ + + +P P L+ L L YEP
Sbjct 237 DIWSAGVTLYNIT-TGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPA 295
Query 855 QRPSFRTI 862
+R S R I
Sbjct 296 KRFSIRQI 303
>sp|O88866|HUNK_MOUSE Hormonally up-regulated neu tumor-associated
kinase OS=Mus musculus OX=10090 GN=Hunk PE=2 SV=1
Length=714
Score = 83.6 bits (205), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 69/213 (32%), Positives = 98/213 (46%), Gaps = 18/213 (8%)
Query 893 HKR---YLKKIRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKAL---KADCGPQHRSGW 944
HKR YL R LGEG F KV L+ TGE VA+K + +A
Sbjct 55 HKRVGNYLIGSRKLGEGSFAKVREGLHVL------TGEKVAIKVIDKKRAKKDTYVTKNL 108
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLF 1003
++E I + + H +I + E E S LVME P G+L + + + A+ +
Sbjct 109 RREGQIQQMIRHPNITQLLDILET--ENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRY 166
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+Q+ + +LH +HRDL N+LLD D +K+ DFGL+ S
Sbjct 167 IRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGS 226
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
P + APE L K+ DVWS GV +Y +LT
Sbjct 227 PAYA-APELLARKKYGPKIDVWSIGVNMYAMLT 258
>sp|Q3UMM4|CDK10_MOUSE Cyclin-dependent kinase 10 OS=Mus musculus
OX=10090 GN=Cdk10 PE=1 SV=1
Length=360
Score = 81.3 bits (199), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 70/214 (33%), Positives = 101/214 (47%), Gaps = 26/214 (12%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDI 950
+ +K+ +GEG +G V Y + T E+VA+K ++ D + + G +EI +
Sbjct 37 KEFEKLNRIGEGTYGIV----YRARDTQTDEIVALKKVRMD---KEKDGIPISSLREITL 89
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQIC 1008
L L H +I++ K +S+ LVM Y L SL + +P AQ+ Q+
Sbjct 90 LLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPT-PFSEAQVKCIMLQVL 148
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP---V 1065
G+ YLH IHRDL N+L+ + VK DFGLA+A Y V +P
Sbjct 149 RGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARA-------YGVPVKPMTPKVVT 201
Query 1066 FWY-APECLKEYKFYYAS-DVWSFGVTLYELLTH 1097
WY APE L S D+W+ G L ELL H
Sbjct 202 LWYRAPELLLGTTTQTTSIDMWAVGCILAELLAH 235
>sp|P34722|KPC1_CAEEL Protein kinase C-like 1 OS=Caenorhabditis
elegans OX=6239 GN=tpa-1 PE=1 SV=2
Length=704
Score = 83.2 bits (204), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 71/220 (32%), Positives = 99/220 (45%), Gaps = 38/220 (17%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH- 958
++ LG+G FGKV L G E A+K LK D E D Y E
Sbjct 378 LKVLGKGSFGKVMLV----ELKGKNEFYAMKCLKKDV--------ILEDDDTECTYIERR 425
Query 959 -IIKYKGC-------CEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICE 1009
+I C C Q + L VMEY+ G L ++ + A+ +A +I
Sbjct 426 VLILASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVV 485
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF--- 1066
+ +LH + I+RDL NVLLD D +K+ DFG+AK RE+G + F
Sbjct 486 ALQFLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMN-------RENGMASTFCGT 538
Query 1067 --WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
+ +PE +K + A D WSFGV +YE+L QSP
Sbjct 539 PDYISPEIIKGQLYNEAVDFWSFGVLMYEMLV----GQSP 574
>sp|Q9Y4K4|M4K5_HUMAN Mitogen-activated protein kinase kinase
kinase kinase 5 OS=Homo sapiens OX=9606 GN=MAP4K5 PE=1 SV=3
Length=846
Score = 83.6 bits (205), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 66/224 (29%), Positives = 106/224 (47%), Gaps = 25/224 (11%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
AD+L NP ++ + ++ +G G +G V Y N TGE+ AVK +K
Sbjct 9 ADILRRNP-----------QQDYELVQRVGSGTYGDV----YKARNVHTGELAAVKIIKL 53
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRH 993
+ G S +QEI +++ H +I+ Y G + L + MEY GSL+D Y
Sbjct 54 EPGDDF-SLIQQEIFMVKECKHCNIVAYFGSY--LSREKLWICMEYCGGGSLQDIYHVTG 110
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ Q+ ++ +G+AYLH + +HRD+ N+LL + VK+ DFG+A +
Sbjct 111 PLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITAT-- 168
Query 1054 YYRVREDGDSPVFWYAPECL---KEYKFYYASDVWSFGVTLYEL 1094
R+ +W APE K + D+W+ G+T EL
Sbjct 169 -IAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIEL 211
Score = 40.8 bits (94), Expect = 0.088, Method: Compositional matrix adjust.
Identities = 51/194 (26%), Positives = 77/194 (40%), Gaps = 33/194 (17%)
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSRE 770
V ++ L+YL K +H ++ G NILL G +KL+D GV +++
Sbjct 120 VCRETLQGLAYLHTKGKMHRDIKGANILLTDHG-------DVKLADFGVAAKITATIAKR 172
Query 771 ERVERIP-WLAPECLP----GGANSLSTAMDKWGFGATLLEI------CFDGEAPLQSRS 819
+ P W+APE GG N L D W G T +E+ FD P+++
Sbjct 173 KSFIGTPYWMAPEVAAVEKNGGYNQLC---DIWAVGITAIELGELQPPMFDLH-PMRALF 228
Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
K +F + + LT P +RP+ +L QP L+ L
Sbjct 229 LMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQP-GLSRALA 287
Query 880 V-------NPDSPA 886
V NPD+ A
Sbjct 288 VELLDKVNNPDNHA 301
>sp|Q9U2Q9|GSK3_CAEEL Glycogen synthase kinase-3 OS=Caenorhabditis
elegans OX=6239 GN=gsk-3 PE=1 SV=1
Length=362
Score = 81.3 bits (199), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 69/209 (33%), Positives = 102/209 (49%), Gaps = 35/209 (17%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V L TN EMVA+K + D ++R E+ I+R L H +I+K
Sbjct 42 IGNGSFGVVFLAKLSTTN----EMVAIKKVLQDKRFKNR-----ELQIMRKLNHPNIVKL 92
Query 963 KGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRH------SIGLAQLLLFAQQICEGMA 1012
K GEK L L++EYVP R + RH I + + L+ Q+ +A
Sbjct 93 KYFFYSSGEKKDELYLNLILEYVPETVYR--VARHYSKQRQQIPMIYVKLYMYQLLRSLA 150
Query 1013 YLHAQHYIHRDLAARNVLLDNDR-LVKIGDFGLAKAVPEGHEYYRVREDGDSPV----FW 1067
Y+H+ HRD+ +N+L+D + ++K+ DFG AK Y VR + + ++
Sbjct 151 YIHSIGICHRDIKPQNLLIDPESGVLKLCDFGSAK--------YLVRNEPNVSYICSRYY 202
Query 1068 YAPECLKEYKFYYAS-DVWSFGVTLYELL 1095
APE + Y S DVWS G + ELL
Sbjct 203 RAPELIFGATNYTNSIDVWSAGTVMAELL 231
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 66/325 (20%), Positives = 131/325 (40%), Gaps = 70/325 (22%)
Query 573 TLNLSQLSFHRVDQK-EITQLSH--LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
T+ ++ ++ VDQ+ EI+ +G G+ V+ +L + + D+
Sbjct 17 TMVVASVATDGVDQQVEISYYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKVLQDK----- 71
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
R + +EL+++ K+ P+ + FY + ++ ++ EY
Sbjct 72 -RFKNRELQIMRKLNHPNIVKLKYFFYSSGEKKDELYLN----------------LILEY 114
Query 690 VEHGPLDVW--LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
V V ++R +PM + + QL +L+Y+ + + H ++ +N+L+
Sbjct 115 VPETVYRVARHYSKQRQQIPMIYVKLYMYQLLRSLAYIHSIGICHRDIKPQNLLI----- 169
Query 748 AEGTSPFIKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGFGATL 804
+ S +KL D G + E V I + APE + G N + ++D W G +
Sbjct 170 -DPESGVLKLCDFGSAKYLVRNEPNVSYICSRYYRAPELIFGATN-YTNSIDVWSAGTVM 227
Query 805 LEI-----CFDGEA------------------PLQSRSPSEKE--------HFYQRQHRL 833
E+ F G++ +QS +P+ KE H + + R+
Sbjct 228 AELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIQSMNPNYKEFKFPQIKAHPWNKVFRV 287
Query 834 PEPSCPQLATLTSQCLTYEPTQRPS 858
P+ + L S+ + Y PT RP+
Sbjct 288 HTPA--EAIDLISKIIEYTPTSRPT 310
>sp|Q9W739|CDK1_RANDY Cyclin-dependent kinase 1 OS=Rana dybowskii
OX=71582 GN=CDK1 PE=2 SV=1
Length=302
Score = 80.5 bits (197), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 70/236 (30%), Positives = 117/236 (50%), Gaps = 29/236 (12%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957
KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L H
Sbjct 6 KIEKIGEGTYGVV----YKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61
Query 958 HIIKYKGCCED--QGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLL--FAQQICEGM 1011
+I+ C D + L L+ E++ + L+ YL G L +L+ + QI +G+
Sbjct 62 NIV----CLLDVLMQDSRLYLIFEFLSM-DLKKYLDSIPSGQYLEAMLVKSYLYQILQGI 116
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWYA 1069
+ HA+ +HRDL +N+L+D+ ++K+ DFGLA+A +P RV +++ A
Sbjct 117 IFCHARRVLHRDLKPQNLLIDSKGVIKLADFGLARAFGIP-----VRVYTHEVVTLWYRA 171
Query 1070 PEC-LKEYKFYYASDVWSFGVTLYEL-----LTHCDSSQSPPTKFLELIGIAQGQM 1119
PE L ++ DVWS G E+ L H DS + EL G ++
Sbjct 172 PEVLLGSVRYSTPVDVWSIGTIFAEIASKKPLFHGDSEIDQLFRISELWGTPNNEV 227
>sp|P48562|CLA4_YEAST Serine/threonine-protein kinase CLA4 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=CLA4 PE=1 SV=1
Length=842
Score = 83.6 bits (205), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 53/180 (29%), Positives = 90/180 (50%), Gaps = 13/180 (7%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
G+ VA+K + P+ + EI +++ H++I+ + + + L +VME++
Sbjct 588 GDKVAIKQMVLSKQPR-KELIVNEILVMKDSRHKNIVNFLEAYL-RTDDDLWVVMEFMEG 645
Query 984 GSLRDYLPR-------HS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035
GSL D + HS + Q+ ++ C+G+ +LH +H IHRD+ + NVLLD
Sbjct 646 GSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRA 705
Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
VKI DFG + + R +W APE +K+ ++ DVWS G+ E+L
Sbjct 706 RVKITDFGFCARLTDKRSK---RATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEML 762
Score = 39.7 bits (91), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 31/143 (22%), Positives = 63/143 (44%), Gaps = 25/143 (17%)
Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENKNLVHGNVCGRNILLA 743
+T+ +E+ P + + H P+ + + ++ L +L +K+++H ++ N+LL
Sbjct 648 LTDIIENSPTN-----DNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLL- 701
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAMDK 797
T +K++D G A ++R +R W+APE + +D
Sbjct 702 ------DTRARVKITD--FGFCARLTDKRSKRATMVGTPYWMAPEVV--KQREYDEKIDV 751
Query 798 WGFGATLLEICFDGEAPLQSRSP 820
W G +E+ +GE P + P
Sbjct 752 WSLGIMTIEM-LEGEPPYLNEDP 773
>sp|Q9LXA5|LRK91_ARATH L-type lectin-domain containing receptor
kinase IX.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK91 PE=1
SV=1
Length=651
Score = 83.2 bits (204), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 84/290 (29%), Positives = 134/290 (46%), Gaps = 40/290 (14%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LGEG FG V Y + MVA+K A Q + + E+ I+ +L H +++
Sbjct 339 RKLGEGGFGAV----YRGYLNSLDMMVAIKKF-AGGSKQGKREFVTEVKIISSLRHRNLV 393
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------------RHSIGLAQLLLFAQQIC 1008
+ G C ++ E ++ E++P GSL +L + ++GLA LL+ +
Sbjct 394 QLIGWCHEKDE--FLMIYEFMPNGSLDAHLFGKKPHLAWHVRCKITLGLASALLYLHEEW 451
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
E Q +HRD+ A NV+LD++ K+GDFGLA+ + HE + G + F Y
Sbjct 452 E-------QCVVHRDIKASNVMLDSNFNAKLGDFGLARLMD--HE-LGPQTTGLAGTFGY 501
Query 1069 -APECLKEYKFYYASDVWSFGVTLYELLT---HCDSSQS---PPTKFLELIGIAQGQMTV 1121
APE + + SDV+SFGV E++T D Q P T +E + G+ V
Sbjct 502 MAPEYISTGRASKESDVYSFGVVTLEIVTGRKSVDRRQGRVEPVTNLVEKMWDLYGKGEV 561
Query 1122 LR-LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ + E L G + +C V C + + RP+ + I +L
Sbjct 562 ITAIDEKLRIGGFDEKQAECLMIVGLW---CAHPDVNTRPSIKQAIQVLN 608
Score = 42.4 bits (98), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 40/158 (25%), Positives = 69/158 (44%), Gaps = 9/158 (6%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F ++S + H +L + G C E +M+ E++ +G LD L ++ H+ + +
Sbjct 377 FVTEVKIISSLRHRNLVQLIGWCHEKDEFLMIYEFMPNGSLDAHLFGKKPHLAWHVRCKI 436
Query 715 AQQLASALSYLE---NKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSRE 770
LASAL YL + +VH ++ N++L + G +L D +G
Sbjct 437 TLGLASALLYLHEEWEQCVVHRDIKASNVMLDSNFNAKLGDFGLARLMDHELGPQTTG-- 494
Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
++APE + G S + D + FG LEI
Sbjct 495 -LAGTFGYMAPEYISTGRASKES--DVYSFGVVTLEIV 529
>sp|Q55FS2|STK4L_DICDI Serine/threonine-protein kinase 4 homolog
B OS=Dictyostelium discoideum OX=44689 GN=krsB PE=3 SV=1
Length=1105
Score = 83.6 bits (205), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 55/197 (28%), Positives = 96/197 (49%), Gaps = 14/197 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I LG G FG V Y T TG +VAVK + + Q +EI+I++ +++
Sbjct 26 IECLGRGSFGSV----YKATYKKTGNIVAVKLVPINEDFQE---ILKEINIMKQCKSKYV 78
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
++Y G +++ ++MEY GS+ D + + Q+ L +G+ YLH
Sbjct 79 VQYYGNYFK--DETCWIIMEYCAFGSVSDMMNITNRVLNEEQIALVCYSTLKGLYYLHRN 136
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ N+L+ + K+ DFG++ + E R R F+ APE ++E
Sbjct 137 SKIHRDIKPGNILVSEEGECKLADFGVSGQL---SERTRKRNTVIGTPFFLAPEVIQEVG 193
Query 1078 FYYASDVWSFGVTLYEL 1094
+ +D+W+ G++ E+
Sbjct 194 YDNKADIWALGISAIEM 210
Score = 38.5 bits (88), Expect = 0.46, Method: Compositional matrix adjust.
Identities = 53/244 (22%), Positives = 90/244 (37%), Gaps = 37/244 (15%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V L P + D E ++M Q ++ +G + ++ EY G +
Sbjct 47 NIVAVKLVPINEDFQEILKE-INIMKQCKSKYVVQYYGNYFKDETCWIIMEYCAFGSVSD 105
Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ + +V L YL + +H ++ NIL++ G KL
Sbjct 106 MMNITNRVLNEEQIALVCYSTLKGLYYLHRNSKIHRDIKPGNILVSEEGEC-------KL 158
Query 758 SDPGVGLGALSREERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEIC---- 808
+D GV G LS R +LAPE + D W G + +E+
Sbjct 159 ADFGVS-GQLSERTRKRNTVIGTPFFLAPEVIQEVG--YDNKADIWALGISAIEMAEFHP 215
Query 809 -FDGEAPLQ-------SRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
+ P++ S SP+ KE P P+ + + CL E +QRPS +
Sbjct 216 PYHDLHPMRVLFMIPTSTSPTLKE---------PHKWSPEFSDFIALCLAKEQSQRPSAK 266
Query 861 TILR 864
+L+
Sbjct 267 DLLK 270
>sp|Q8VCR8|MYLK2_MOUSE Myosin light chain kinase 2, skeletal/cardiac
muscle OS=Mus musculus OX=10090 GN=Mylk2 PE=1 SV=2
Length=613
Score = 83.2 bits (204), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 61/198 (31%), Positives = 99/198 (50%), Gaps = 15/198 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V C T TG +A K +K P+ + EI+++ L H ++I+
Sbjct 308 LGGGKFGAV-CTC---TERATGLKLAAKVIKKQT-PKDKEMVLLEIEVMNQLNHRNLIQL 362
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020
E E + L MEY+ G L + + L ++ ++F +QIC+G+ ++H +
Sbjct 363 YAAIETSHE--IILFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVL 420
Query 1021 HRDLAARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
H DL N+L N LVKI DFGLA+ + +++ + +P F +PE + +
Sbjct 421 HLDLKPENILCVNTTGHLVKIIDFGLARRY---NPNEKLKVNFGTPEF-LSPEVVNYDQI 476
Query 1079 YYASDVWSFGVTLYELLT 1096
+D+WS GV Y LL+
Sbjct 477 SDKTDMWSLGVITYMLLS 494
Score = 38.5 bits (88), Expect = 0.43, Method: Compositional matrix adjust.
Identities = 40/180 (22%), Positives = 75/180 (42%), Gaps = 24/180 (13%)
Query 632 DRGQELRVVLKVLD---PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+R L++ KV+ P ++ L E +M+Q++H +L ++ E I+ E
Sbjct 321 ERATGLKLAAKVIKKQTPKDKEMVLLEIE---VMNQLNHRNLIQLYAAIETSHEIILFME 377
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
Y+E G L + E H+ MV +Q+ + ++ ++H ++ NIL
Sbjct 378 YIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNT--- 434
Query 749 EGTSPFIKLSDPGVGLGALSREERVERIP-------WLAPECLPGGANSLSTAMDKWGFG 801
T +K+ D G R E++ +L+PE + + +S D W G
Sbjct 435 --TGHLVKIID----FGLARRYNPNEKLKVNFGTPEFLSPEVV--NYDQISDKTDMWSLG 486
>sp|Q55GE6|ROCO7_DICDI Probable serine/threonine-protein kinase
roco7 OS=Dictyostelium discoideum OX=44689 GN=roco7 PE=3 SV=1
Length=2615
Score = 84.0 bits (206), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 81/332 (24%), Positives = 148/332 (45%), Gaps = 58/332 (17%)
Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926
T++ ++LA +T N + + P LK LG G + V ++ G
Sbjct 1749 TKIDIYSLAFEVTFNSNKFSVIP----YETLKFGPQLGSGSYANVYRGIWN------GSE 1798
Query 927 VAVKALKADCGPQHRSG----WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982
VA+K L D G + + ++ E I L H + + G LV E +
Sbjct 1799 VAIKVLNFDDGHANTTEKYREFRNEAHITGELRHANTVSLMGV----SLSPFCLVTELLQ 1854
Query 983 LGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHA--QHYIHRDLAARNVLL---DNDR 1035
G L ++ + +L A + +GM +LH+ +HRDL + N+LL D
Sbjct 1855 YGDLAKFIRNTAETFSWGTVLKLAIDVAKGMNFLHSCKPMIVHRDLKSANILLGGSSMDN 1914
Query 1036 LV-KIGDFGLA-----KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
LV K+GDFGL+ K V +G + + R W APEC+ + ++ D++S+ +
Sbjct 1915 LVAKVGDFGLSIKPIGKEV-KGRKVWNWR--------WLAPECMGDGQYTEKIDIYSYAI 1965
Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE----RGERLPRPDKCPCEVY 1145
L+E++T P ++++ L+ ++E +G R P++CP ++
Sbjct 1966 VLWEIITR----DLPFEEYVDQ----------LKWNSIIEDKIMKGLRPTIPNECPPDMK 2011
Query 1146 HLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
L+ +CW + RP+F +++ L T+ + +
Sbjct 2012 QLITDCWSGDPKKRPSFNSILERLSTMQKTFN 2043
Score = 58.5 bits (140), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 57/252 (23%), Positives = 112/252 (44%), Gaps = 21/252 (8%)
Query 633 RGQELRVVLKVLDPSHHDIALAFYE---TASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G E+ + + D H + + E A + ++ H + + GV + +VTE
Sbjct 1795 NGSEVAIKVLNFDDGHANTTEKYREFRNEAHITGELRHANTVSLMGVSLS--PFCLVTEL 1852
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGL 747
+++G L ++R + +A +A +++L + +VH ++ NILL G
Sbjct 1853 LQYGDLAKFIRNTAETFSWGTVLKLAIDVAKGMNFLHSCKPMIVHRDLKSANILL---GG 1909
Query 748 AEGTSPFIKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGFGATL 804
+ + K+ D G+ + + +E + ++ WLAPEC+ G + +D + + L
Sbjct 1910 SSMDNLVAKVGDFGLSIKPIGKEVKGRKVWNWRWLAPECM--GDGQYTEKIDIYSYAIVL 1967
Query 805 LEIC-----FDGEAP-LQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPS 858
EI F+ L+ S E + + +P P + L + C + +P +RPS
Sbjct 1968 WEIITRDLPFEEYVDQLKWNSIIEDKIMKGLRPTIPNECPPDMKQLITDCWSGDPKKRPS 2027
Query 859 FRTILRDLTRLQ 870
F +IL L+ +Q
Sbjct 2028 FNSILERLSTMQ 2039
>sp|Q8KY50|STKP_STREE Serine/threonine-protein kinase StkP OS=Streptococcus
pneumoniae OX=1313 GN=stkP PE=1 SV=1
Length=659
Score = 83.2 bits (204), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 63/209 (30%), Positives = 100/209 (48%), Gaps = 11/209 (5%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEI 948
+F RY + ++ +G G V L D DG E VAVK L+ + P + +++E
Sbjct 7 IFAGRY-RIVKQIGRGGMADVYL-AKDLILDG--EEVAVKVLRTNYQTDPIAVARFQREA 62
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQI 1007
+ L H HI++ E+ G++ L MEYV L+ Y+ H + + + +QI
Sbjct 63 RAMADLDHPHIVRITDIGEEDGQQ--YLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMRQI 120
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
M H + +HRDL +N+LL D K+ DFG+A A E G V +
Sbjct 121 LLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVAFAETSLTQTNSMLGS--VHY 178
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+PE + K SD+++ G+ YE+LT
Sbjct 179 LSPEQARGSKATVQSDIYAMGIIFYEMLT 207
Score = 35.0 bits (79), Expect = 5.0, Method: Compositional matrix adjust.
Identities = 43/192 (22%), Positives = 87/192 (45%), Gaps = 27/192 (14%)
Query 639 VVLKVLDPSHHD--IALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +KVL ++ IA+A F A M+ + H H+ + + + + EYV L
Sbjct 39 VAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDL 98
Query 696 DVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
+++ H P++ + V +Q+ A+ + +VH ++ +NILL G A
Sbjct 99 KRYIKE---HYPLSNEEAVRIMRQILLAMRLAHTRGIVHRDLKPQNILLTPDGTA----- 150
Query 754 FIKLSDPGVGLG----ALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLE-- 806
K++D G+ + +L++ + + +L+PE G ++ + D + G E
Sbjct 151 --KVTDFGIAVAFAETSLTQTNSMLGSVHYLSPEQARGSKATVQS--DIYAMGIIFYEML 206
Query 807 ---ICFDGEAPL 815
I +DG++ +
Sbjct 207 TGHIPYDGDSAV 218
>sp|Q6C3J2|IPL1_YARLI Spindle assembly checkpoint kinase OS=Yarrowia
lipolytica (strain CLIB 122 / E 150) OX=284591 GN=IPL1
PE=3 SV=1
Length=371
Score = 81.3 bits (199), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 64/225 (28%), Positives = 104/225 (46%), Gaps = 21/225 (9%)
Query 879 TVNPDSPASDPTVFHKRYLKKI---RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--K 933
T +P SP + T F L + LG+G FGKV L + TG + A+K + K
Sbjct 78 TTDPPSPLTGITGFRNYSLDDFEIGKALGKGKFGKVYLV----KDKKTGFVSALKCMEKK 133
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--- 990
+++E++I L H ++++ G D+ + L++EYV G L L
Sbjct 134 ELVEGNVEKQFRREVEIQSNLRHTNVLRLFGHFHDKDR--VYLILEYVVHGELYKLLRNQ 191
Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
R + A ++ Q+ E + YLH ++ IHRD+ N+LL + +KI DFG + P
Sbjct 192 KRFTESTASSYIY--QMSEALLYLHGKNIIHRDIKPENILLHFNDTIKISDFGWSVHAPS 249
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
R + + PE ++ + DVWS G+ +YE L
Sbjct 250 NR-----RSTLCGTMDYLPPEIVQSRPYDKNVDVWSLGILMYEFL 289
Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 57/231 (25%), Positives = 97/231 (42%), Gaps = 23/231 (10%)
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
++ F + S + HT++ + G ++ EYV HG L LR ++
Sbjct 139 NVEKQFRREVEIQSNLRHTNVLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTEST 198
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS- 768
+ Q ++ AL YL KN++H ++ NILL + IK+SD G + A S
Sbjct 199 ASSYIYQ-MSEALLYLHGKNIIHRDIKPENILLH-------FNDTIKISDFGWSVHAPSN 250
Query 769 -REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE-ICFDGEAPLQSRSPSEKEHF 826
R + +L PE + + +D W G + E +C G P + P +
Sbjct 251 RRSTLCGTMDYLPPEIV--QSRPYDKNVDVWSLGILMYEFLC--GAPPFE--EPGGAQAT 304
Query 827 YQR----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD--LTRLQP 871
Y+R R+P A L + LT +P +R + + + + RL+P
Sbjct 305 YRRIVKLDLRIPPYVSADAADLIKRMLTLDPAKRFKLKDMHKHPWIVRLRP 355
>sp|Q9LHP4|RGI1_ARATH LRR receptor-like serine/threonine-protein
kinase RGI1 OS=Arabidopsis thaliana OX=3702 GN=RGI1 PE=1
SV=1
Length=1141
Score = 83.6 bits (205), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 90/298 (30%), Positives = 138/298 (46%), Gaps = 35/298 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQH-------RSGWKQEIDILRTL 954
+G+G G V Y D N GE++AVK L A H R + E+ L T+
Sbjct 792 IGKGCSGVV--YRADVDN---GEVIAVKKLWPAMVNGGHDEKTKNVRDSFSAEVKTLGTI 846
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLA-----QLLLFAQQIC 1008
H++I+++ GCC ++ + L+ +Y+P GSL L R L ++LL A Q
Sbjct 847 RHKNIVRFLGCCWNRNTR--LLMYDYMPNGSLGSLLHERRGSSLDWDLRYRILLGAAQ-- 902
Query 1009 EGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
G+AYLH +HRD+ A N+L+ D I DFGLAK V EG + R
Sbjct 903 -GLAYLHHDCLPPIVHRDIKANNILIGLDFEPYIADFGLAKLVDEG-DIGRCSNTVAGSY 960
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVL 1122
+ APE K SDV+S+GV + E+LT D + ++ + +G + VL
Sbjct 961 GYIAPEYGYSMKITEKSDVYSYGVVVLEVLTGKQPIDPTVPEGIHLVDWVRQNRGSLEVL 1020
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180
T L R E D+ +V C + RPT +++ +LK + ++ + A
Sbjct 1021 DST-LRSRTE--AEADEM-MQVLGTALLCVNSSPDERPTMKDVAAMLKEIKQEREEYA 1074
Score = 34.7 bits (78), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 48/203 (24%), Positives = 84/203 (41%), Gaps = 29/203 (14%)
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D ++ +F + + H ++ G C +++ +Y+ +G L L RG
Sbjct 826 DEKTKNVRDSFSAEVKTLGTIRHKNIVRFLGCCWNRNTRLLMYDYMPNGSLGSLLHERRG 885
Query 705 HVPMAWKMVVAQQLASA--LSYLENKNL---VHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ W + L +A L+YL + L VH ++ NIL +GL P+I
Sbjct 886 S-SLDWDLRYRILLGAAQGLAYLHHDCLPPIVHRDIKANNIL---IGL--DFEPYI---- 935
Query 760 PGVGLGALSREERVERIP--------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
GL L E + R ++APE G + ++ D + +G +LE+ G
Sbjct 936 ADFGLAKLVDEGDIGRCSNTVAGSYGYIAPEY--GYSMKITEKSDVYSYGVVVLEV-LTG 992
Query 812 EAPLQSRSPSEKEHF--YQRQHR 832
+ P+ P E H + RQ+R
Sbjct 993 KQPIDPTVP-EGIHLVDWVRQNR 1014
>sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo
sapiens OX=9606 GN=NUAK1 PE=1 SV=1
Length=661
Score = 83.2 bits (204), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 58/197 (29%), Positives = 98/197 (50%), Gaps = 14/197 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960
LG+G +GKV T +G +VA+K+++ D Q ++EI+I+ +L H HII
Sbjct 61 LGKGTYGKVK----RATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHII 116
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
E++ + + ++MEY G L DY+ R + + F +QI + Y H
Sbjct 117 SIYEVFENKDK--IVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGV 174
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDL N+LLD++ +KI DFGL+ ++ + + + +PE + +
Sbjct 175 VHRDLKLENILLDDNCNIKIADFGLSNL----YQKDKFLQTFCGSPLYASPEIVNGRPYR 230
Query 1080 YAS-DVWSFGVTLYELL 1095
D W+ GV LY L+
Sbjct 231 GPEVDSWALGVLLYTLV 247
Score = 37.0 bits (84), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 14/153 (9%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
+MS ++H H+ ++ V + +++ EY G L ++ ER + +Q+ S
Sbjct 106 IMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYI-SERRRLSERETRHFFRQIVS 164
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---- 776
A+ Y +VH ++ NILL + IK++D GL L ++++ +
Sbjct 165 AVHYCHKNGVVHRDLKLENILL-------DDNCNIKIAD--FGLSNLYQKDKFLQTFCGS 215
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
P A + G +D W G L + +
Sbjct 216 PLYASPEIVNGRPYRGPEVDSWALGVLLYTLVY 248
>sp|Q9SXB4|Y1130_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g11300 OS=Arabidopsis thaliana OX=3702
GN=At1g11300 PE=2 SV=1
Length=820
Score = 83.2 bits (204), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 72/211 (34%), Positives = 98/211 (46%), Gaps = 22/211 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG P G G+ +AVK L G Q E+ ++ L H ++
Sbjct 515 LGQGGFG--------PVYKGKLQEGQEIAVKRLSRASG-QGLEELVNEVVVISKLQHRNL 565
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLF--AQQICEGMAYLH 1015
+K GCC E+ LV E++P SL YL R + L F IC G+ YLH
Sbjct 566 VKLLGCCIAGEER--MLVYEFMPKKSLDYYLFDSRRAKLLDWKTRFNIINGICRGLLYLH 623
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
IHRDL A N+LLD + + KI DFGLA+ P + R + + APE
Sbjct 624 RDSRLRIIHRDLKASNILLDENLIPKISDFGLARIFPGNEDEANTRRVVGTYGY-MAPEY 682
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
F SDV+S GV L E+++ +S S
Sbjct 683 AMGGLFSEKSDVFSLGVILLEIISGRRNSNS 713
Score = 43.5 bits (101), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 57/226 (25%), Positives = 89/226 (39%), Gaps = 45/226 (20%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
+ LGQG VY+G+L+ GQE+ V K L +
Sbjct 513 NKLGQGGFGPVYKGKLQ-----------------------EGQEIAV--KRLSRASGQGL 547
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK- 711
++S++ H +L + G C+ G E ++V E++ LD +L R + WK
Sbjct 548 EELVNEVVVISKLQHRNLVKLLGCCIAGEERMLVYEFMPKKSLDYYLFDSRRAKLLDWKT 607
Query 712 -MVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LG 765
+ + L YL + ++H ++ NIL L E P K+SD G+
Sbjct 608 RFNIINGICRGLLYLHRDSRLRIIHRDLKASNIL-----LDENLIP--KISDFGLARIFP 660
Query 766 ALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
E R+ ++APE GG S D + G LLEI
Sbjct 661 GNEDEANTRRVVGTYGYMAPEYAMGGL--FSEKSDVFSLGVILLEI 704
>sp|Q4WHP3|STE20_ASPFU Serine/threonine-protein kinase ste20 OS=Aspergillus
fumigatus (strain ATCC MYA-4609 / CBS 101355 /
FGSC A1100 / Af293) OX=330879 GN=ste20 PE=3 SV=2
Length=815
Score = 83.2 bits (204), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 55/208 (26%), Positives = 98/208 (47%), Gaps = 14/208 (7%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DPT + K +G+G G V Y GT VA+K + D P+ + E
Sbjct 529 DPTKLYYNLNK----IGQGASGGV----YTAYQHGTNNCVAIKQMNLDLQPK-KELIINE 579
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +++ H++I+ + + L +VMEY+ GSL D + + + Q+ ++
Sbjct 580 ILVMKDSKHKNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMTEGQIAAVCRET 637
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
G+ +LH++ IHRD+ + N+LL D +K+ DFG + ++ R +W
Sbjct 638 LNGLQHLHSKGVIHRDIKSDNILLSLDGNIKLTDFGFCAQI---NDSQNKRNTMVGTPYW 694
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095
APE + ++ D+WS G+ E++
Sbjct 695 MAPEVVTRKEYGRKVDIWSLGIMAIEMI 722
Score = 37.0 bits (84), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 42/165 (25%), Positives = 69/165 (42%), Gaps = 18/165 (11%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719
+M H ++ + G + +V EY+E G L DV +A V ++
Sbjct 582 VMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVVTFNIMTEGQIA---AVCRETL 638
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERVER 775
+ L +L +K ++H ++ NILL+ G IKL+D G + R V
Sbjct 639 NGLQHLHSKGVIHRDIKSDNILLSLDG-------NIKLTDFGFCAQINDSQNKRNTMVGT 691
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
W+APE + +D W G +E+ +GE P + SP
Sbjct 692 PYWMAPEVV--TRKEYGRKVDIWSLGIMAIEM-IEGEPPYLTESP 733
>sp|Q9SJG2|Y2296_ARATH Probable receptor-like protein kinase At2g42960
OS=Arabidopsis thaliana OX=3702 GN=At2g42960 PE=3 SV=1
Length=494
Score = 82.4 bits (202), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 81/284 (29%), Positives = 130/284 (46%), Gaps = 25/284 (9%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG +G V Y N G VAVK L + G Q ++ E++ + + H+++
Sbjct 186 VNVLGEGGYGVV--YRGKLVN---GTEVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNL 239
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYL 1014
++ G C + + LV EYV G+L +L ++ + + +AYL
Sbjct 240 VRLLGYCIEGVHR--MLVYEYVNSGNLEQWLHGAMRQHGNLTWEARMKIITGTAQALAYL 297
Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-AP 1070
H +HRD+ A N+L+D++ K+ DFGLAK + G + R G F Y AP
Sbjct 298 HEAIEPKVVHRDIKASNILIDDEFNAKLSDFGLAKLLDSGESHITTRVMG---TFGYVAP 354
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E SD++SFGV L E +T D P + L+ + + R E+++
Sbjct 355 EYANTGLLNEKSDIYSFGVLLLEAITGRDPVDYGRPANEVNLVEWLKMMVGTRRAEEVVD 414
Query 1130 RGERL-PRPDKCPCEVYHLMK-NCWETEASFRPTFENLIPILKT 1171
RL PRP K + L+ C + EA RP + +L++
Sbjct 415 --PRLEPRPSKSALKRALLVSLRCVDPEAEKRPRMSQVARMLES 456
Score = 53.5 bits (127), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 61/234 (26%), Positives = 94/234 (40%), Gaps = 39/234 (17%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR---RERGHVPMAWKMVVAQQL 718
+ V H +L + G C+ G ++V EYV G L+ WL R+ G++ +M +
Sbjct 231 IGHVRHKNLVRLLGYCIEGVHRMLVYEYVNSGNLEQWLHGAMRQHGNLTWEARMKIITGT 290
Query 719 ASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE- 774
A AL+YL +VH ++ NIL+ A KLSD G+ S E +
Sbjct 291 AQALAYLHEAIEPKVVHRDIKASNILIDDEFNA-------KLSDFGLAKLLDSGESHITT 343
Query 775 ----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-- 828
++APE G L+ D + FG LLE G P+ P+ + + +
Sbjct 344 RVMGTFGYVAPEYANTGL--LNEKSDIYSFGVLLLE-AITGRDPVDYGRPANEVNLVEWL 400
Query 829 ---------------RQHRLPEPSCPQLATLTS-QCLTYEPTQRPSFRTILRDL 866
R P S + A L S +C+ E +RP + R L
Sbjct 401 KMMVGTRRAEEVVDPRLEPRPSKSALKRALLVSLRCVDPEAEKRPRMSQVARML 454
>sp|A9SR33|M2K1B_PHYPA Mitogen-activated protein kinase kinase
1b OS=Physcomitrium patens OX=3218 GN=MKK1b PE=2 SV=2
Length=342
Score = 80.9 bits (198), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 60/201 (30%), Positives = 100/201 (50%), Gaps = 13/201 (6%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ +R LG+G G V L + TND + A+K ++ + R QE+ I + H
Sbjct 66 LEAVRVLGKGAGGSVQLVRHKWTND----IYALKGIQMNINETVRKQIVQELKINQLTLH 121
Query 957 E--HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAY 1013
+ +I+K G + +V+EY+ GSL D + + I L + + Q+ +G+ Y
Sbjct 122 QCPYIVKCYHSFYHNG--IISIVLEYMDRGSLADIIKQTKQIPEPYLAVISNQVLKGLNY 179
Query 1014 LH-AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
LH +H IHRD+ N+L++ VKI DFG++ + R+ + +PE
Sbjct 180 LHQVRHIIHRDIKPSNLLINQKGEVKISDFGVSAVLISSMAQ---RDTFVGTYTYMSPER 236
Query 1073 LKEYKFYYASDVWSFGVTLYE 1093
L + Y SD+WS G+T+ E
Sbjct 237 LGGQSYAYDSDIWSLGLTILE 257
>sp|Q8T0S6|HIPPO_DROME Serine/threonine-protein kinase hippo OS=Drosophila
melanogaster OX=7227 GN=hpo PE=1 SV=1
Length=669
Score = 83.2 bits (204), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 54/194 (28%), Positives = 94/194 (48%), Gaps = 14/194 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG +G V Y + + +VA+K + + +EI I++ ++++Y
Sbjct 48 LGEGSYGSV----YKAVHKESSSIVAIKLVPVESDLHE---IIKEISIMQQCDSPYVVRY 100
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G Q + L + MEY GS+ D L + ++ ++ +G+ YLH + I
Sbjct 101 YGSYFKQYD--LWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKI 158
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 159 HRDIKAANILLNTEGYAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVIEEIGYDC 215
Query 1081 ASDVWSFGVTLYEL 1094
+D+WS G+T E+
Sbjct 216 VADIWSLGITALEM 229
Score = 41.6 bits (96), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 47/213 (22%), Positives = 83/213 (39%), Gaps = 20/213 (9%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S+M Q ++ +G + + + EY G + +R + + +
Sbjct 87 SIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTL 146
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
L YL + +H ++ NILL T + KL+D GV +++ V
Sbjct 147 QGLVYLHLRRKIHRDIKAANILL-------NTEGYAKLADFGVAGQLTDTMAKRNTVIGT 199
Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830
P W+APE + G + ++ D W G T LE+ +G+ P P ++
Sbjct 200 PFWMAPEVIEEIGYDCVA---DIWSLGITALEMA-EGKPPYGEIHPMRAIFMIPQKPPPS 255
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
R P+ + S+CL EP R + +L
Sbjct 256 FREPDRWSTEFIDFVSKCLVKEPDDRATATELL 288
>sp|C0LGV0|Y5487_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At5g48740 OS=Arabidopsis thaliana OX=3702
GN=At5g48740 PE=1 SV=1
Length=895
Score = 83.2 bits (204), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 71/249 (29%), Positives = 110/249 (44%), Gaps = 26/249 (10%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
QR R I R ++Q N + + + A+ R K++ +G G FG V
Sbjct 573 QRNKERDITRAQLKMQNWNASRIFSHKEIKSAT-------RNFKEV--IGRGSFGAV--- 620
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
DG V V+ + G + E+ +L + H++++ ++G C + K
Sbjct 621 YRGKLPDGKQVAVKVRFDRTQLGAD---SFINEVHLLSQIRHQNLVSFEGFCYE--PKRQ 675
Query 975 QLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAA 1026
LV EY+ GSL D+L RHS+ L A +G+ YLH IHRD+ +
Sbjct 676 ILVYEYLSGGSLADHLYGPRSKRHSLNWVSRLKVAVDAAKGLDYLHNGSEPRIIHRDVKS 735
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
N+LLD D K+ DFGL+K + + + + PE + SDV+S
Sbjct 736 SNILLDKDMNAKVSDFGLSKQFTKADASH-ITTVVKGTAGYLDPEYYSTLQLTEKSDVYS 794
Query 1087 FGVTLYELL 1095
FGV L EL+
Sbjct 795 FGVVLLELI 803
Score = 45.4 bits (106), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 53/179 (30%), Positives = 73/179 (41%), Gaps = 28/179 (16%)
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---RRERGHVPM 708
A +F L+SQ+ H +L G C I+V EY+ G L L R +R +
Sbjct 644 ADSFINEVHLLSQIRHQNLVSFEGFCYEPKRQILVYEYLSGGSLADHLYGPRSKRHSLNW 703
Query 709 AWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
++ VA A L YL N + ++H +V NILL + A K+SD GL
Sbjct 704 VSRLKVAVDAAKGLDYLHNGSEPRIIHRDVKSSNILLDKDMNA-------KVSD--FGLS 754
Query 766 ALSREERVERIP--------WLAPECLPGGANSLSTAMDKWGFGATLLE-ICFDGEAPL 815
+ I +L PE L+ D + FG LLE IC G PL
Sbjct 755 KQFTKADASHITTVVKGTAGYLDPEYY--STLQLTEKSDVYSFGVVLLELIC--GREPL 809
>sp|P13185|KIN1_YEAST Serine/threonine protein kinase KIN1 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=KIN1 PE=1 SV=3
Length=1064
Score = 83.6 bits (205), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 71/242 (29%), Positives = 105/242 (43%), Gaps = 47/242 (19%)
Query 889 PTVFHKRYLKK---IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW- 944
P FH++ L + +G G GKV L + TN+ + +A KA H+
Sbjct 109 PKQFHRKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFL---HKEQML 165
Query 945 ---KQEIDIL-----------------------RTLYHEHIIKYKGCCEDQGEKSLQLVM 978
K E D+L + LYH HI + C ++
Sbjct 166 PPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNH--FYMLF 223
Query 979 EYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037
EYV G L DY+ +H SI Q FA+ I + YLHA + +HRDL N+++ + +
Sbjct 224 EYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEI 283
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDS---PVFWYAPECLKEYKFYYAS-DVWSFGVTLYE 1093
KI DFGL+ Y R+ + +++ APE LK + DVWSFGV L+
Sbjct 284 KIIDFGLSN-------IYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFV 336
Query 1094 LL 1095
L+
Sbjct 337 LV 338
Score = 47.4 bits (111), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 52/209 (25%), Positives = 92/209 (44%), Gaps = 14/209 (7%)
Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQL 718
ASL + H H+ + +C M+ EYV G L ++ + G + A+ +
Sbjct 195 ASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYII-QHGSIREHQARKFARGI 253
Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER---VER 775
ASAL YL N+VH ++ NI+++ S IK+ D G+ SR++
Sbjct 254 ASALIYLHANNIVHRDLKIENIMIS-------DSSEIKIIDFGLSNIYDSRKQLHTFCGS 306
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE-KEHFYQRQHRLP 834
+ + APE L + +D W FG L + G+ P + S E Q + P
Sbjct 307 LYFAAPELLKANPYT-GPEVDVWSFGVVLF-VLVCGKVPFDDENSSVLHEKIKQGKVEYP 364
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
+ ++ +L S+ L +P +R + + ++
Sbjct 365 QHLSIEVISLLSKMLVVDPKRRATLKQVV 393
>sp|F1LP90|MINK1_RAT Misshapen-like kinase 1 OS=Rattus norvegicus
OX=10116 GN=Mink1 PE=1 SV=2
Length=1336
Score = 83.6 bits (205), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 62/206 (30%), Positives = 101/206 (49%), Gaps = 24/206 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961
+G G +G+V Y + TG++ A+K + D KQEI++L+ +H +I
Sbjct 31 VGNGTYGQV----YKGRHVKTGQLAAIKVM--DVTEDEEEEIKQEINMLKKYSHHRNIAT 84
Query 962 YKGCCEDQ----GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ----LLLFAQQICEGMAY 1013
Y G + + L LVME+ GS+ D L +++ G A + ++I G+A+
Sbjct 85 YYGAFIKKSPPGNDDQLWLVMEFCGAGSVTD-LVKNTKGNALKEDCIAYICREILRGLAH 143
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
LHA IHRD+ +NVLL + VK+ DFG++ + R +W APE +
Sbjct 144 LHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---DRTVGRRNTFIGTPYWMAPEVI 200
Query 1074 K-----EYKFYYASDVWSFGVTLYEL 1094
+ + Y SD+WS G+T E+
Sbjct 201 ACDENPDATYDYRSDIWSLGITAIEM 226
Score = 37.0 bits (84), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 42/191 (22%), Positives = 80/191 (42%), Gaps = 22/191 (12%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG--PENI----MVTEYVEH 692
+KV+D + + E L H ++A +G ++ P N +V E+
Sbjct 51 AAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGA 110
Query 693 GPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G + ++ +G+ + + +++ L++L ++H ++ G+N+LL
Sbjct 111 GSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTE------- 163
Query 752 SPFIKLSDPGVGLG---ALSREERVERIP-WLAPECLPGGANSLST---AMDKWGFGATL 804
+ +KL D GV + R P W+APE + N +T D W G T
Sbjct 164 NAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITA 223
Query 805 LEICFDGEAPL 815
+E+ +G PL
Sbjct 224 IEMA-EGAPPL 233
>sp|A0A2I0BVG8|CDPK1_PLAFO Calcium-dependent protein kinase 1
OS=Plasmodium falciparum (isolate NF54) OX=5843 GN=PDCK1 PE=1
SV=1
Length=524
Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 67/212 (32%), Positives = 100/212 (47%), Gaps = 23/212 (11%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK-----------ALKADCGPQHRSGWKQE 947
K+R LG G +G+V L C + G + +K K +C + E
Sbjct 58 KVRKLGSGAYGEV-LLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEIYNE 116
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQ 1006
I +L++L H +IIK ED+ K LV E+ G L + RH +Q
Sbjct 117 ISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQ 174
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDS 1063
I G+ YLH + +HRD+ N+LL+N +KI DFGL+ + + ++R D
Sbjct 175 ILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDN---KLR-DRLG 230
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
++ APE L++ K+ DVWS GV LY LL
Sbjct 231 TAYYIAPEVLRK-KYNEKCDVWSCGVILYILL 261
Score = 38.5 bits (88), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 54/232 (23%), Positives = 90/232 (39%), Gaps = 29/232 (13%)
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVWLRRE 702
D H +I Y SL+ + H ++ + V +VTE+ E G L + R +
Sbjct 107 DKIHEEI----YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHK 162
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
A + +Q+ S + YL N+VH ++ NILL E + +
Sbjct 163 FDECDAA---NIMKQILSGICYLHKHNIVHRDIKPENILL------ENKHSLLNIKIVDF 213
Query 763 GLGA-LSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATL-LEIC----FDGE 812
GL + S++ +R+ ++APE L N D W G L + +C F G+
Sbjct 214 GLSSFFSKDNKLRDRLGTAYYIAPEVLRKKYNE---KCDVWSCGVILYILLCGYPPFGGQ 270
Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
EK +Y + S + L LTY+ +R + + L
Sbjct 271 NDQDIIKKVEKGKYYFDFNDWKNIS-EEAKELIKLMLTYDYNKRITAKEALN 321
>sp|P62343|CDPK1_PLAFK Calcium-dependent protein kinase 1 OS=Plasmodium
falciparum (isolate K1 / Thailand) OX=5839 GN=CDPK1
PE=1 SV=2
Length=524
Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 67/212 (32%), Positives = 100/212 (47%), Gaps = 23/212 (11%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK-----------ALKADCGPQHRSGWKQE 947
K+R LG G +G+V L C + G + +K K +C + E
Sbjct 58 KVRKLGSGAYGEV-LLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEIYNE 116
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQ 1006
I +L++L H +IIK ED+ K LV E+ G L + RH +Q
Sbjct 117 ISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQ 174
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDS 1063
I G+ YLH + +HRD+ N+LL+N +KI DFGL+ + + ++R D
Sbjct 175 ILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDN---KLR-DRLG 230
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
++ APE L++ K+ DVWS GV LY LL
Sbjct 231 TAYYIAPEVLRK-KYNEKCDVWSCGVILYILL 261
Score = 38.5 bits (88), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 54/232 (23%), Positives = 90/232 (39%), Gaps = 29/232 (13%)
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVWLRRE 702
D H +I Y SL+ + H ++ + V +VTE+ E G L + R +
Sbjct 107 DKIHEEI----YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHK 162
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
A + +Q+ S + YL N+VH ++ NILL E + +
Sbjct 163 FDECDAA---NIMKQILSGICYLHKHNIVHRDIKPENILL------ENKHSLLNIKIVDF 213
Query 763 GLGA-LSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATL-LEIC----FDGE 812
GL + S++ +R+ ++APE L N D W G L + +C F G+
Sbjct 214 GLSSFFSKDNKLRDRLGTAYYIAPEVLRKKYNE---KCDVWSCGVILYILLCGYPPFGGQ 270
Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
EK +Y + S + L LTY+ +R + + L
Sbjct 271 NDQDIIKKVEKGKYYFDFNDWKNIS-EEAKELIKLMLTYDYNKRITAKEALN 321
>sp|P62344|CDPK1_PLAF7 Calcium-dependent protein kinase 1 OS=Plasmodium
falciparum (isolate 3D7) OX=36329 GN=CDPK1 PE=1 SV=2
Length=524
Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 67/212 (32%), Positives = 100/212 (47%), Gaps = 23/212 (11%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK-----------ALKADCGPQHRSGWKQE 947
K+R LG G +G+V L C + G + +K K +C + E
Sbjct 58 KVRKLGSGAYGEV-LLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEIYNE 116
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQ 1006
I +L++L H +IIK ED+ K LV E+ G L + RH +Q
Sbjct 117 ISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQ 174
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDS 1063
I G+ YLH + +HRD+ N+LL+N +KI DFGL+ + + ++R D
Sbjct 175 ILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDN---KLR-DRLG 230
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
++ APE L++ K+ DVWS GV LY LL
Sbjct 231 TAYYIAPEVLRK-KYNEKCDVWSCGVILYILL 261
Score = 38.5 bits (88), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 54/232 (23%), Positives = 90/232 (39%), Gaps = 29/232 (13%)
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVWLRRE 702
D H +I Y SL+ + H ++ + V +VTE+ E G L + R +
Sbjct 107 DKIHEEI----YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHK 162
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
A + +Q+ S + YL N+VH ++ NILL E + +
Sbjct 163 FDECDAA---NIMKQILSGICYLHKHNIVHRDIKPENILL------ENKHSLLNIKIVDF 213
Query 763 GLGA-LSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATL-LEIC----FDGE 812
GL + S++ +R+ ++APE L N D W G L + +C F G+
Sbjct 214 GLSSFFSKDNKLRDRLGTAYYIAPEVLRKKYNE---KCDVWSCGVILYILLCGYPPFGGQ 270
Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
EK +Y + S + L LTY+ +R + + L
Sbjct 271 NDQDIIKKVEKGKYYFDFNDWKNIS-EEAKELIKLMLTYDYNKRITAKEALN 321
>sp|Q7YQL3|PAK3_PONPY Serine/threonine-protein kinase PAK 3 OS=Pongo
pygmaeus OX=9600 GN=PAK3 PE=2 SV=1
Length=559
Score = 82.8 bits (203), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 59/209 (28%), Positives = 98/209 (47%), Gaps = 16/209 (8%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP + R+ K +G+G G V Y + TG+ VA+K + P+ + E
Sbjct 278 DPKKKYTRFEK----IGQGASGTV----YTALDIATGQEVAIKQMNLQQQPK-KELIINE 328
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I ++R + +I+ Y E L +VMEY+ GSL D + + Q+ ++
Sbjct 329 ILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCREC 386
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066
+ + +LH+ IHRD+ + N+LL D VK+ DFG A+ PE + R +
Sbjct 387 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 442
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095
W APE + + D+WS G+ E++
Sbjct 443 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 471
>sp|Q7YQL4|PAK3_PANTR Serine/threonine-protein kinase PAK 3 OS=Pan
troglodytes OX=9598 GN=PAK3 PE=2 SV=1
Length=559
Score = 82.8 bits (203), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 59/209 (28%), Positives = 98/209 (47%), Gaps = 16/209 (8%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP + R+ K +G+G G V Y + TG+ VA+K + P+ + E
Sbjct 278 DPKKKYTRFEK----IGQGASGTV----YTALDIATGQEVAIKQMNLQQQPK-KELIINE 328
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I ++R + +I+ Y E L +VMEY+ GSL D + + Q+ ++
Sbjct 329 ILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCREC 386
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066
+ + +LH+ IHRD+ + N+LL D VK+ DFG A+ PE + R +
Sbjct 387 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 442
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095
W APE + + D+WS G+ E++
Sbjct 443 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 471
>sp|O75914|PAK3_HUMAN Serine/threonine-protein kinase PAK 3 OS=Homo
sapiens OX=9606 GN=PAK3 PE=1 SV=2
Length=559
Score = 82.8 bits (203), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 59/209 (28%), Positives = 98/209 (47%), Gaps = 16/209 (8%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP + R+ K +G+G G V Y + TG+ VA+K + P+ + E
Sbjct 278 DPKKKYTRFEK----IGQGASGTV----YTALDIATGQEVAIKQMNLQQQPK-KELIINE 328
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I ++R + +I+ Y E L +VMEY+ GSL D + + Q+ ++
Sbjct 329 ILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCREC 386
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066
+ + +LH+ IHRD+ + N+LL D VK+ DFG A+ PE + R +
Sbjct 387 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 442
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095
W APE + + D+WS G+ E++
Sbjct 443 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 471
>sp|Q09170|CDS1_SCHPO Serine/threonine-protein kinase cds1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=cds1 PE=1 SV=2
Length=460
Score = 82.0 bits (201), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 77/244 (32%), Positives = 111/244 (45%), Gaps = 19/244 (8%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAV----KALKADCGPQHRSGWKQEIDILRTLY 955
IR LG G F V L N G + + K L + +++EIDIL++L+
Sbjct 170 IRTLGSGTFAVVKLAV--EVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSLH 227
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYL 1014
H +++ E+ E L +VMEYV G L D+L + SI +Q+ E + +L
Sbjct 228 HPGVVQCHEIFENDDE--LFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHL 285
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H Q HRD+ N+L+ ND +KI DFGLAK + H E + + APE LK
Sbjct 286 HKQGVTHRDIKPENILITNDFHLKISDFGLAKVI---HGTGTFLETFCGTMGYLAPEVLK 342
Query 1075 EYK------FYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
+ D+WS G LY +LT + S K +ELI + L E+
Sbjct 343 SKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEI 402
Query 1128 LERG 1131
E G
Sbjct 403 SEEG 406
>sp|Q62829|PAK3_RAT Serine/threonine-protein kinase PAK 3 OS=Rattus
norvegicus OX=10116 GN=Pak3 PE=1 SV=1
Length=544
Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 59/209 (28%), Positives = 98/209 (47%), Gaps = 16/209 (8%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP + R+ K +G+G G V Y + TG+ VA+K + P+ + E
Sbjct 263 DPKKKYTRFEK----IGQGASGTV----YTALDIATGQEVAIKQMNLQQQPK-KELIINE 313
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I ++R + +I+ Y E L +VMEY+ GSL D + + Q+ ++
Sbjct 314 ILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCREC 371
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066
+ + +LH+ IHRD+ + N+LL D VK+ DFG A+ PE + R +
Sbjct 372 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 427
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095
W APE + + D+WS G+ E++
Sbjct 428 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 456
Score = 33.9 bits (76), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 40/150 (27%), Positives = 64/150 (43%), Gaps = 26/150 (17%)
Query 680 GPENIMVTEYVEHGPL-DVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736
G E +V EY+ G L DV + G + V ++ AL +L + ++H ++
Sbjct 335 GDELWVVMEYLAGGSLTDVVTETCMDEGQI-----AAVCRECLQALDFLHSNQVIHRDIK 389
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANS 790
NILL G +KL+D G A E+ +R W+APE + A
Sbjct 390 SDNILL-------GMDGSVKLTD--FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-- 438
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+D W G +E+ +GE P + +P
Sbjct 439 YGPKVDIWSLGIMAIEMV-EGEPPYLNENP 467
>sp|Q942F3|BRI1_ORYSJ Brassinosteroid LRR receptor kinase BRI1
OS=Oryza sativa subsp. japonica OX=39947 GN=BRI1 PE=1 SV=1
Length=1121
Score = 83.6 bits (205), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 81/288 (28%), Positives = 132/288 (46%), Gaps = 33/288 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V G++VA+K L G R + E++ + + H +++
Sbjct 813 IGSGGFGDVY-----KAQLKDGKVVAIKKLIHVSGQGDRE-FTAEMETIGKIKHRNLVPL 866
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQIC----EGMAYLHAQ 1017
G C+ GE+ L LV +Y+ GSL D L R IG ++I G+A+LH
Sbjct 867 LGYCK-AGEERL-LVYDYMKFGSLEDVLHDRKKIGKKLNWEARRKIAVGAARGLAFLHHN 924
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H IHRD+ + NVL+D ++ DFG+A+ + + V +P + PE +
Sbjct 925 CIPHIIHRDMKSSNVLIDEQLEARVSDFGMARLMSVVDTHLSVSTLAGTPGY-VPPEYYQ 983
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE------LIGIAQGQMTVLRLTELL 1128
++ DV+S+GV L ELLT PPT + L+G + Q T L++T++
Sbjct 984 SFRCTTKGDVYSYGVVLLELLTG-----KPPTDSADFGEDNNLVGWVK-QHTKLKITDVF 1037
Query 1129 ERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILKTVH 1173
+ E L E+ +K C + S RPT ++ + K +
Sbjct 1038 DP-ELLKEDPSVELELLEHLKIACACLDDRPSRRPTMLKVMAMFKEIQ 1084
Score = 35.4 bits (80), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 52/264 (20%), Positives = 110/264 (42%), Gaps = 39/264 (15%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAW--K 711
F + ++ H +L + G C G E ++V +Y++ G L DV R++ + W +
Sbjct 848 FTAEMETIGKIKHRNLVPLLGYCKAGEERLLVYDYMKFGSLEDVLHDRKKIGKKLNWEAR 907
Query 712 MVVAQQLASALSYLENK---NLVHGNVCGRNILL-----ARLGLAEGTSPFIKLSDPGVG 763
+A A L++L + +++H ++ N+L+ AR+ G + + + D +
Sbjct 908 RKIAVGAARGLAFLHHNCIPHIIHRDMKSSNVLIDEQLEARVS-DFGMARLMSVVDTHLS 966
Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ L+ ++ PE + +T D + +G LLE+ G+ P S E
Sbjct 967 VSTLAGTP-----GYVPPEYYQ--SFRCTTKGDVYSYGVVLLEL-LTGKPPTDSADFGED 1018
Query 824 EHF--YQRQH---RLPEPSCPQL--------------ATLTSQCLTYEPTQRPSFRTILR 864
+ + +QH ++ + P+L + CL P++RP+ ++
Sbjct 1019 NNLVGWVKQHTKLKITDVFDPELLKEDPSVELELLEHLKIACACLDDRPSRRPTMLKVMA 1078
Query 865 DLTRLQPHNLADVLTVNPDSPASD 888
+Q + D T + + + D
Sbjct 1079 MFKEIQAGSTVDSKTSSAAAGSID 1102
>sp|O22971|CIPKD_ARATH CBL-interacting serine/threonine-protein
kinase 13 OS=Arabidopsis thaliana OX=3702 GN=CIPK13 PE=1 SV=2
Length=502
Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 76/233 (33%), Positives = 115/233 (49%), Gaps = 33/233 (14%)
Query 879 TVNPDSPASDPT-----VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933
T P+SP S T + K + K+ LG G F KV Y N +GE VA+K +
Sbjct 36 TSTPESPRSPRTPQGSILMDKYEIGKL--LGHGSFAKV----YLARNIHSGEDVAIKVI- 88
Query 934 ADCGPQHRSGW----KQEIDILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRD 988
D +SG K+EI ILR + H +I+ E K+ + +VMEYV G L +
Sbjct 89 -DKEKIVKSGLAGHIKREISILRRVRHPYIVH---LLEVMATKTKIYIVMEYVRGGELYN 144
Query 989 YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ R + + QQ+ +A+ H++ HRDL N+LLD+ VK+ DFGL+ V
Sbjct 145 TVARGRLREGTARRYFQQLISSVAFCHSRGVYHRDLKLENLLLDDKGNVKVSDFGLS-VV 203
Query 1049 PEGHEYYRVREDGDSPVF-----WYAPECLKEYKFYYA-SDVWSFGVTLYELL 1095
E +++++G F + APE L + A +D+WS GV L+ L+
Sbjct 204 SE-----QLKQEGICQTFCGTPAYLAPEVLTRKGYEGAKADIWSCGVILFVLM 251
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 76/304 (25%), Positives = 125/304 (41%), Gaps = 49/304 (16%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
SPRT S L +D+ EI +L LG G+ VY R SG+ K+ D++ +V
Sbjct 44 SPRTPQGSIL----MDKYEIGKL--LGHGSFAKVYLAR--NIHSGEDVAIKVIDKEKIVK 95
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G R + S++ +V H ++ + V + +V EY
Sbjct 96 SGLAGHIKREI-------------------SILRRVRHPYIVHLLEVMATKTKIYIVMEY 136
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
V G L + R R A + QQL S++++ ++ + H ++ N+LL G
Sbjct 137 VRGGELYNTVARGRLREGTARRYF--QQLISSVAFCHSRGVYHRDLKLENLLLDDKG--- 191
Query 750 GTSPFIKLSDPGVGLGALSREERVERI--------PWLAPECLPGGANSLSTAMDKWGFG 801
+K+SD GL +S + + E I +LAPE L + A D W G
Sbjct 192 ----NVKVSD--FGLSVVSEQLKQEGICQTFCGTPAYLAPEVLTRKGYEGAKA-DIWSCG 244
Query 802 ATLLEICFDGEAPLQSRSP-SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
L + G P ++ Y+ Q + P+ P+LA L ++ L P R +
Sbjct 245 VILF-VLMAGYLPFDDKNILVMYTKIYKGQFKCPKWFSPELARLVTRMLDTNPDTRITIP 303
Query 861 TILR 864
I++
Sbjct 304 EIMK 307
>sp|O64781|Y1639_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61390 OS=Arabidopsis thaliana OX=3702
GN=At1g61390 PE=3 SV=1
Length=831
Score = 83.2 bits (204), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 66/203 (33%), Positives = 99/203 (49%), Gaps = 22/203 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG P G G+ +AVK L + G Q + EI ++ L H+++
Sbjct 526 LGQGGFG--------PVYKGKLVDGKEIAVKRLSSSSG-QGTDEFMNEIRLISKLQHKNL 576
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015
++ GCC +GE+ L L+ EY+ SL +L + I + Q + G+ YLH
Sbjct 577 VRLLGCCI-KGEEKL-LIYEYLVNKSLDVFLFDSTLKFEIDWQKRFNIIQGVARGLLYLH 634
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
IHRDL N+LLD + KI DFGLA+ + +G +Y + + APE
Sbjct 635 RDSRLRVIHRDLKVSNILLDEKMIPKISDFGLAR-MSQGTQYQDNTRRVVGTLGYMAPEY 693
Query 1073 LKEYKFYYASDVWSFGVTLYELL 1095
F SD++SFGV L E++
Sbjct 694 AWTGVFSEKSDIYSFGVLLLEII 716
Score = 57.0 bits (136), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 61/244 (25%), Positives = 103/244 (42%), Gaps = 43/244 (18%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
+NL + R + + LGQG VY+G+L V G++
Sbjct 505 VNLFDMHTIRTATNNFSSSNKLGQGGFGPVYKGKL-------------------VDGKE- 544
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ +K L S F L+S++ H +L + G C++G E +++ EY+ +
Sbjct 545 -----IAVKRLSSSSGQGTDEFMNEIRLISKLQHKNLVRLLGCCIKGEEKLLIYEYLVNK 599
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
LDV+L + W + + Q +A L YL + + V R++ ++ + L E
Sbjct 600 SLDVFLFDSTLKFEIDWQKRFNIIQGVARGLLYLHRDSRLR--VIHRDLKVSNILLDEKM 657
Query 752 SPFIKLSDPGVGLGALSREER--------VERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
P K+SD GL +S+ + V + ++APE G S D + FG
Sbjct 658 IP--KISD--FGLARMSQGTQYQDNTRRVVGTLGYMAPEYAWTGV--FSEKSDIYSFGVL 711
Query 804 LLEI 807
LLEI
Sbjct 712 LLEI 715
>sp|A4IFM7|MYLK2_BOVIN Myosin light chain kinase 2, skeletal/cardiac
muscle OS=Bos taurus OX=9913 GN=MYLK2 PE=2 SV=1
Length=623
Score = 82.8 bits (203), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 61/198 (31%), Positives = 99/198 (50%), Gaps = 15/198 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V C T TG +A K +K P+ + EI+++ L H ++I+
Sbjct 318 LGGGKFGAV-CTC---TEKATGLKLAAKVIKKQT-PKDKEMVLLEIEVMNQLNHRNLIQL 372
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020
E E + L MEY+ G L + + L ++ ++F +QIC+G+ ++H +
Sbjct 373 YAAIETPHE--IVLFMEYIEGGELFERIVDEDYQLTEVDTMVFVRQICDGILFMHKMRVL 430
Query 1021 HRDLAARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
H DL N+L N LVKI DFGLA+ + +++ + +P F +PE + +
Sbjct 431 HLDLKPENILCVNTTGHLVKIIDFGLARRY---NPNEKLKVNFGTPEF-LSPEVVNYDQI 486
Query 1079 YYASDVWSFGVTLYELLT 1096
+D+WS GV Y LL+
Sbjct 487 SDKTDMWSLGVITYMLLS 504
Score = 34.7 bits (78), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 38/172 (22%), Positives = 69/172 (40%), Gaps = 27/172 (16%)
Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
V+K P ++ L E +M+Q++H +L ++ E ++ EY+E G L +
Sbjct 342 VIKKQTPKDKEMVLLEIE---VMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERI 398
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL----------LARLGLAE 749
E + MV +Q+ + ++ ++H ++ NIL + GLA
Sbjct 399 VDEDYQLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLAR 458
Query 750 GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
+P KL V G +L+PE + + +S D W G
Sbjct 459 RYNPNEKLK---VNFGTPE---------FLSPEVV--NYDQISDKTDMWSLG 496
>sp|Q8SRF5|Y823_ENCCU Probable cell division protein kinase ECU08_0230
OS=Encephalitozoon cuniculi (strain GB-M1) OX=284813
GN=ECU08_0230 PE=3 SV=1
Length=265
Score = 79.3 bits (194), Expect = 9e-15, Method: Composition-based stats.
Identities = 61/202 (30%), Positives = 100/202 (50%), Gaps = 27/202 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G +G+V Y+ + T E VA+K ++ + +EI IL+ L H +II
Sbjct 10 IGSGTYGEV----YEAIDTETKEKVALKRIRLNEKEGMPGTALREISILKKLSHRNIISL 65
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ----LLLFAQQICEGMAYLHAQH 1018
+ L +V ++ DY + IG+ + L Q IC G+ YLH +
Sbjct 66 VSII--HTDALLTMVFPFI------DYELKKYIGMNTGKNIMELVNQLIC-GVHYLHRMN 116
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECL---K 1074
+HRDL +N+L+ +D ++KI DFGL++++ E + WY +PE L
Sbjct 117 VVHRDLKPQNILVTSDGVLKIADFGLSRSL----EIRVPPYSSEVVTLWYRSPELLMGST 172
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
Y+FY D+WS G +YE++T
Sbjct 173 SYRFYV--DIWSLGCIIYEMIT 192
>sp|Q9LYN8|EMS1_ARATH Leucine-rich repeat receptor protein kinase
EMS1 OS=Arabidopsis thaliana OX=3702 GN=EMS1 PE=1 SV=1
Length=1192
Score = 83.6 bits (205), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 69/212 (33%), Positives = 104/212 (49%), Gaps = 24/212 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTL 954
+ K +G+G FG V C GE VAVK L ++ Q + E++ L +
Sbjct 916 HFSKKNIIGDGGFGTVYKACL------PGEKTVAVKKL-SEAKTQGNREFMAEMETLGKV 968
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI------C 1008
H +++ G C EK LV EY+ GSL +L R+ G+ ++L +++++
Sbjct 969 KHPNLVSLLGYCSFSEEK--LLVYEYMVNGSLDHWL-RNQTGMLEVLDWSKRLKIAVGAA 1025
Query 1009 EGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
G+A+LH H IHRD+ A N+LLD D K+ DFGLA+ + + G
Sbjct 1026 RGLAFLHHGFIPHIIHRDIKASNILLDGDFEPKVADFGLARLISACESHVSTVIAG---T 1082
Query 1066 FWYA-PECLKEYKFYYASDVWSFGVTLYELLT 1096
F Y PE + + DV+SFGV L EL+T
Sbjct 1083 FGYIPPEYGQSARATTKGDVYSFGVILLELVT 1114
Score = 47.4 bits (111), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 63/264 (24%), Positives = 111/264 (42%), Gaps = 40/264 (15%)
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
E V +K L + F + +V H +L + G C E ++V EY+ +G L
Sbjct 939 EKTVAVKKLSEAKTQGNREFMAEMETLGKVKHPNLVSLLGYCSFSEEKLLVYEYMVNGSL 998
Query 696 DVWLRRERGHVP-MAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAE 749
D WLR + G + + W ++ +A A L++L + +++H ++ NILL +
Sbjct 999 DHWLRNQTGMLEVLDWSKRLKIAVGAARGLAFLHHGFIPHIIHRDIKASNILL------D 1052
Query 750 GT-SPFIKLSDPGVGLGALSREERVERI-----PWLAPECLPGGANSLSTAMDKWGFGAT 803
G P K++D G+ + E V + ++ PE G + +T D + FG
Sbjct 1053 GDFEP--KVADFGLARLISACESHVSTVIAGTFGYIPPEY--GQSARATTKGDVYSFGVI 1108
Query 804 LLEICFDGEAPLQSRSPSEKEHF----YQRQHR-----LPEPSCPQLATLTSQ------- 847
LLE+ E SE + Q+ ++ + +P +A SQ
Sbjct 1109 LLELVTGKEPTGPDFKESEGGNLVGWAIQKINQGKAVDVIDPLLVSVALKNSQLRLLQIA 1168
Query 848 --CLTYEPTQRPSFRTILRDLTRL 869
CL P +RP+ +L+ L +
Sbjct 1169 MLCLAETPAKRPNMLDVLKALKEI 1192
>sp|Q61036|PAK3_MOUSE Serine/threonine-protein kinase PAK 3 OS=Mus
musculus OX=10090 GN=Pak3 PE=1 SV=2
Length=559
Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 59/209 (28%), Positives = 98/209 (47%), Gaps = 16/209 (8%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP + R+ K +G+G G V Y + TG+ VA+K + P+ + E
Sbjct 278 DPKKKYTRFEK----IGQGASGTV----YTALDIATGQEVAIKQMNLQQQPK-KELIINE 328
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I ++R + +I+ Y E L +VMEY+ GSL D + + Q+ ++
Sbjct 329 ILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCREC 386
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066
+ + +LH+ IHRD+ + N+LL D VK+ DFG A+ PE + R +
Sbjct 387 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 442
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095
W APE + + D+WS G+ E++
Sbjct 443 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 471
Score = 34.3 bits (77), Expect = 9.3, Method: Compositional matrix adjust.
Identities = 40/150 (27%), Positives = 64/150 (43%), Gaps = 26/150 (17%)
Query 680 GPENIMVTEYVEHGPL-DVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736
G E +V EY+ G L DV + G + V ++ AL +L + ++H ++
Sbjct 350 GDELWVVMEYLAGGSLTDVVTETCMDEGQI-----AAVCRECLQALDFLHSNQVIHRDIK 404
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANS 790
NILL G +KL+D G A E+ +R W+APE + A
Sbjct 405 SDNILL-------GMDGSVKLTD--FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-- 453
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+D W G +E+ +GE P + +P
Sbjct 454 YGPKVDIWSLGIMAIEMV-EGEPPYLNENP 482
>sp|Q4KM47|CDK10_RAT Cyclin-dependent kinase 10 OS=Rattus norvegicus
OX=10116 GN=Cdk10 PE=2 SV=1
Length=358
Score = 80.9 bits (198), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 70/214 (33%), Positives = 101/214 (47%), Gaps = 26/214 (12%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDI 950
+ +K+ +GEG +G V Y + T E+VA+K ++ D + + G +EI +
Sbjct 35 KEFEKLNRIGEGTYGIV----YRARDTQTDEIVALKKVRMD---KEKDGIPISSLREITL 87
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQIC 1008
L L H +I++ K +S+ LVM Y L SL + +P AQ+ Q+
Sbjct 88 LLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPT-PFSEAQVKCILLQVL 146
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP---V 1065
G+ YLH IHRDL N+L+ + VK DFGLA+A Y V +P
Sbjct 147 RGLQYLHRSFIIHRDLKVSNLLMTDKGCVKTADFGLARA-------YGVPVKPMTPKVVT 199
Query 1066 FWY-APECLKEYKFYYAS-DVWSFGVTLYELLTH 1097
WY APE L S D+W+ G L ELL H
Sbjct 200 LWYRAPELLLGTTTQTTSIDMWAVGCILAELLAH 233
>sp|P07313|MYLK2_RABIT Myosin light chain kinase 2, skeletal/cardiac
muscle OS=Oryctolagus cuniculus OX=9986 GN=MYLK2 PE=1
SV=3
Length=608
Score = 82.8 bits (203), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 61/198 (31%), Positives = 99/198 (50%), Gaps = 15/198 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V C T TG +A K +K P+ + EI+++ L H ++I+
Sbjct 303 LGGGKFGAV-CTC---TEKSTGLKLAAKVIKKQT-PKDKEMVMLEIEVMNQLNHRNLIQL 357
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020
E E + L MEY+ G L + + L ++ ++F +QIC+G+ ++H +
Sbjct 358 YAAIETPHE--IVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVL 415
Query 1021 HRDLAARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
H DL N+L N LVKI DFGLA+ + +++ + +P F +PE + +
Sbjct 416 HLDLKPENILCVNTTGHLVKIIDFGLARRY---NPNEKLKVNFGTPEF-LSPEVVNYDQI 471
Query 1079 YYASDVWSFGVTLYELLT 1096
+D+WS GV Y LL+
Sbjct 472 SDKTDMWSLGVITYMLLS 489
Score = 35.4 bits (80), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 38/172 (22%), Positives = 70/172 (41%), Gaps = 27/172 (16%)
Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
V+K P ++ + E +M+Q++H +L ++ E ++ EY+E G L +
Sbjct 327 VIKKQTPKDKEMVMLEIE---VMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERI 383
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL----------LARLGLAE 749
E H+ MV +Q+ + ++ ++H ++ NIL + GLA
Sbjct 384 VDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLAR 443
Query 750 GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
+P KL V G +L+PE + + +S D W G
Sbjct 444 RYNPNEKLK---VNFGTPE---------FLSPEVV--NYDQISDKTDMWSLG 481
>sp|P34099|KAPC_DICDI cAMP-dependent protein kinase catalytic
subunit OS=Dictyostelium discoideum OX=44689 GN=pkaC PE=1 SV=2
Length=648
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 65/203 (32%), Positives = 99/203 (49%), Gaps = 17/203 (8%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTL 954
K+IR +G G FGKV Y T DG A+K L Q + E IL ++
Sbjct 336 FKQIRVIGTGTFGKV--YLIQNTKDGC--YYAMKCLNKAYVVQLKQVEHLNSEKSILSSI 391
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL--LFAQQICEGMA 1012
+H I+ +D EK L L+ EYV G + +L R S+ + +A +I +
Sbjct 392 HHPFIVNLYQAFQD--EKKLYLLFEYVAGGEVFTHL-RKSMKFSNSTAKFYAAEIVLALE 448
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+LH Q+ ++RDL N+L+DN +KI DFG AK V + R +P + APE
Sbjct 449 FLHKQNIVYRDLKPENLLIDNQGHIKITDFGFAKRVED-----RTFTLCGTPEYL-APEI 502
Query 1073 LKEYKFYYASDVWSFGVTLYELL 1095
++ A D W+ G+ ++E+L
Sbjct 503 IQSKGHGKAVDWWALGILIFEML 525
Score = 38.5 bits (88), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 34/150 (23%), Positives = 64/150 (43%), Gaps = 11/150 (7%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S++S + H + ++ + ++ EYV G + LR+ K A+ +
Sbjct 386 SILSSIHHPFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAE-IV 444
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-W 778
AL +L +N+V+ ++ N+L+ G IK++D G R + P +
Sbjct 445 LALEFLHKQNIVYRDLKPENLLIDNQG-------HIKITDFGFAKRVEDRTFTLCGTPEY 497
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEIC 808
LAPE + + A+D W G + E+
Sbjct 498 LAPEIIQSKGH--GKAVDWWALGILIFEML 525
>sp|P45894|AAPK1_CAEEL 5'-AMP-activated protein kinase catalytic
subunit alpha-1 OS=Caenorhabditis elegans OX=6239 GN=aak-1
PE=2 SV=2
Length=589
Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 75/228 (33%), Positives = 111/228 (49%), Gaps = 25/228 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK----ADCGPQHRSGWKQEIDILRTLYHEH 958
+G+G FG V T+ TG VA+K L G +++ + EID L+ L H H
Sbjct 30 IGKGAFGAVK----RGTHIQTGYDVAIKILNRGRMKGLGTVNKT--RNEIDNLQKLTHPH 83
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQ 1017
I + + + LVME V G L Y+ R ++ + + + QQI G++Y H
Sbjct 84 ITRLFRVISTPSD--IFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNH 141
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL N+LLD ++ +KI DFGL+ + +G + SP + APE + K
Sbjct 142 MIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGD---LLSTACGSP-NYAAPELISN-K 196
Query 1078 FYYA--SDVWSFGVTLYELL--THCDSSQSPPTKFLELIGIAQGQMTV 1121
Y D+WS GV LY +L T Q+ PT F + I G+ TV
Sbjct 197 LYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAK---IKSGRYTV 241
Score = 40.4 bits (93), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 46/212 (22%), Positives = 84/212 (40%), Gaps = 24/212 (11%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA 721
+ +++H H+ + V + +V E V G L ++ R +G +P+ QQ+ S
Sbjct 76 LQKLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITR-KGALPIRESRRYFQQIISG 134
Query 722 LSYLENKNLVHGNV--------CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
+SY N +VH ++ +NI +A GL+ + LS G + E +
Sbjct 135 VSYCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGDLLS-TACGSPNYAAPELI 193
Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHR 832
++ PE +D W G L + G P ++ P+ ++
Sbjct 194 SNKLYVGPE------------VDLWSCGVILYAMLC-GTLPFDDQNVPTLFAKIKSGRYT 240
Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+P Q A L S L +P +R + I+
Sbjct 241 VPYSMEKQAADLISTMLQVDPVKRADVKRIVN 272
>sp|O65479|CRK20_ARATH Putative cysteine-rich receptor-like protein
kinase 20 OS=Arabidopsis thaliana OX=3702 GN=CRK20 PE=2
SV=2
Length=666
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 86/289 (30%), Positives = 129/289 (45%), Gaps = 34/289 (12%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I LG+G FG+V + +G VAVK L + G Q ++ E+ ++ L H ++
Sbjct 347 INKLGQGGFGEVYKGTFP-----SGVQVAVKRLSKNSG-QGEKEFENEVVVVAKLQHRNL 400
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYL 1014
+K G C + EK L V E+VP SL DY QL I G+ YL
Sbjct 401 VKLLGYCLEGEEKIL--VYEFVPNKSL-DYFLFDPTMQGQLDWSRRYKIIGGIARGILYL 457
Query 1015 HAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
H IHRDL A N+LLD D K+ DFG+A+ R + + APE
Sbjct 458 HQDSRLTIIHRDLKAGNILLDADMNPKVADFGMARIFGMDQTEANTRRVVGT-YGYMAPE 516
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL-RL------ 1124
KF SDV+SFGV + E+++ +S ++ G +T RL
Sbjct 517 YAMYGKFSMKSDVYSFGVLVLEIVSGMKNS-----SLDQMDGSISNLVTYTWRLWSNGSP 571
Query 1125 TELLE--RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+EL++ G+ + C H+ C + +A+ RPT ++ +L T
Sbjct 572 SELVDPSFGDNYQTSEITRC--IHIALLCVQEDANDRPTMSAIVQMLTT 618
Score = 43.9 bits (102), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 44/182 (24%), Positives = 83/182 (46%), Gaps = 20/182 (11%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
++V +K L + F +++++ H +L + G C+ G E I+V E+V + LD
Sbjct 367 VQVAVKRLSKNSGQGEKEFENEVVVVAKLQHRNLVKLLGYCLEGEEKILVYEFVPNKSLD 426
Query 697 VWLR--RERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGT 751
+L +G + + + + +A + YL + ++H ++ NIL L
Sbjct 427 YFLFDPTMQGQLDWSRRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNIL-----LDADM 481
Query 752 SPFIKLSDPGVG--LGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLL 805
+P K++D G+ G E R+ ++APE G S+ + D + FG +L
Sbjct 482 NP--KVADFGMARIFGMDQTEANTRRVVGTYGYMAPEYAMYGKFSMKS--DVYSFGVLVL 537
Query 806 EI 807
EI
Sbjct 538 EI 539
>sp|Q8N4C8|MINK1_HUMAN Misshapen-like kinase 1 OS=Homo sapiens
OX=9606 GN=MINK1 PE=1 SV=2
Length=1332
Score = 83.6 bits (205), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 62/206 (30%), Positives = 101/206 (49%), Gaps = 24/206 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961
+G G +G+V Y + TG++ A+K + D KQEI++L+ +H +I
Sbjct 31 VGNGTYGQV----YKGRHVKTGQLAAIKVM--DVTEDEEEEIKQEINMLKKYSHHRNIAT 84
Query 962 YKGCCEDQ----GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ----LLLFAQQICEGMAY 1013
Y G + + L LVME+ GS+ D L +++ G A + ++I G+A+
Sbjct 85 YYGAFIKKSPPGNDDQLWLVMEFCGAGSVTD-LVKNTKGNALKEDCIAYICREILRGLAH 143
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
LHA IHRD+ +NVLL + VK+ DFG++ + R +W APE +
Sbjct 144 LHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---DRTVGRRNTFIGTPYWMAPEVI 200
Query 1074 K-----EYKFYYASDVWSFGVTLYEL 1094
+ + Y SD+WS G+T E+
Sbjct 201 ACDENPDATYDYRSDIWSLGITAIEM 226
Score = 36.6 bits (83), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 42/191 (22%), Positives = 80/191 (42%), Gaps = 22/191 (12%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG--PENI----MVTEYVEH 692
+KV+D + + E L H ++A +G ++ P N +V E+
Sbjct 51 AAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGA 110
Query 693 GPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G + ++ +G+ + + +++ L++L ++H ++ G+N+LL
Sbjct 111 GSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTE------- 163
Query 752 SPFIKLSDPGVGLG---ALSREERVERIP-WLAPECLPGGANSLST---AMDKWGFGATL 804
+ +KL D GV + R P W+APE + N +T D W G T
Sbjct 164 NAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITA 223
Query 805 LEICFDGEAPL 815
+E+ +G PL
Sbjct 224 IEMA-EGAPPL 233
>sp|Q03963|E2AK2_MOUSE Interferon-induced, double-stranded RNA-activated
protein kinase OS=Mus musculus OX=10090 GN=Eif2ak2
PE=1 SV=2
Length=515
Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 69/253 (27%), Positives = 117/253 (46%), Gaps = 33/253 (13%)
Query 878 LTVNPDSPASDPTVFHKRY---LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+ V+PD + R+ + I ++G G FG+V + + G+ A+K +K
Sbjct 220 VKVSPDDVQRNKYTLDARFNSDFEDIEEIGLGGFGQV----FKAKHRIDGKRYAIKRVKY 275
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED--------------QGEKSLQLVMEY 980
+ + E+ L L H +I++Y C E + L + ME+
Sbjct 276 NT-----EKAEHEVQALAELNHVNIVQYHSCWEGVDYDPEHSMSDTSRYKTRCLFIQMEF 330
Query 981 VPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037
G+L ++ + + A +L +QI G+ Y+H++ IHRDL N+ L ++R +
Sbjct 331 CDKGTLEQWMRNRNQSKVDKALILDLYEQIVTGVEYIHSKGLIHRDLKPGNIFLVDERHI 390
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
KIGDFGLA A+ E R R G + + +PE L + D+++ G+ L ELL
Sbjct 391 KIGDFGLATAL-ENDGKSRTRRTG--TLQYMSPEQLFLKHYGKEVDIFALGLILAELLHT 447
Query 1098 CDSSQSPPTKFLE 1110
C ++S KF E
Sbjct 448 C-FTESEKIKFFE 459
>sp|Q96RR4|KKCC2_HUMAN Calcium/calmodulin-dependent protein kinase
kinase 2 OS=Homo sapiens OX=9606 GN=CAMKK2 PE=1 SV=2
Length=588
Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 52/150 (35%), Positives = 77/150 (51%), Gaps = 6/150 (4%)
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ 1005
QEI IL+ L H +++K +D E L +V E V G + + + Q + Q
Sbjct 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQ 294
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
+ +G+ YLH Q IHRD+ N+L+ D +KI DFG++ +G + G +P
Sbjct 295 DLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF-KGSDALLSNTVG-TPA 352
Query 1066 FWYAPECLKEYKFYY---ASDVWSFGVTLY 1092
F APE L E + + A DVW+ GVTLY
Sbjct 353 FM-APESLSETRKIFSGKALDVWAMGVTLY 381
>sp|O08815|SLK_RAT STE20-like serine/threonine-protein kinase
OS=Rattus norvegicus OX=10116 GN=Slk PE=1 SV=1
Length=1206
Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 61/205 (30%), Positives = 99/205 (48%), Gaps = 23/205 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I +LG+G FGKV Y N T + A K + + + EIDIL + H +I
Sbjct 37 IGELGDGAFGKV----YKAQNKETNVLAAAKVIDTKS-EEELEDYMVEIDILASCDHPNI 91
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQ 1017
+K E +L +++E+ G++ + + +Q+ + +Q E + YLH
Sbjct 92 VKLLDAF--YYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDN 149
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---FWYAPECL- 1073
IHRDL A N+L D +K+ DFG++ + R + DS + +W APE +
Sbjct 150 KIIHRDLKAGNILFTLDGDIKLADFGVS------AKNTRTIQRRDSFIGTPYWMAPEVVM 203
Query 1074 ----KEYKFYYASDVWSFGVTLYEL 1094
K+ + Y +DVWS G+TL E+
Sbjct 204 CETSKDRPYDYKADVWSLGITLIEM 228
Score = 40.4 bits (93), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 38/132 (29%), Positives = 57/132 (43%), Gaps = 16/132 (12%)
Query 685 MVTEYVEHGPLD-VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
++ E+ G +D V L ER + + VV +Q AL+YL + ++H ++ NIL
Sbjct 106 ILIEFCAGGAVDAVMLELERP-LTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFT 164
Query 744 RLGLAEGTSPFIKLSDPGVGLG---ALSREERVERIP-WLAPE---CLPGGANSLSTAMD 796
G IKL+D GV + R + P W+APE C D
Sbjct 165 LDG-------DIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKAD 217
Query 797 KWGFGATLLEIC 808
W G TL+E+
Sbjct 218 VWSLGITLIEMA 229
>sp|Q9JM52|MINK1_MOUSE Misshapen-like kinase 1 OS=Mus musculus
OX=10090 GN=Mink1 PE=1 SV=3
Length=1308
Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 62/206 (30%), Positives = 101/206 (49%), Gaps = 24/206 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961
+G G +G+V Y + TG++ A+K + D KQEI++L+ +H +I
Sbjct 31 VGNGTYGQV----YKGRHVKTGQLAAIKVM--DVTEDEEEEIKQEINMLKKYSHHRNIAT 84
Query 962 YKGCCEDQ----GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ----LLLFAQQICEGMAY 1013
Y G + + L LVME+ GS+ D L +++ G A + ++I G+A+
Sbjct 85 YYGAFIKKSPPGNDDQLWLVMEFCGAGSVTD-LVKNTKGNALKEDCIAYICREILRGLAH 143
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
LHA IHRD+ +NVLL + VK+ DFG++ + R +W APE +
Sbjct 144 LHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---DRTVGRRNTFIGTPYWMAPEVI 200
Query 1074 K-----EYKFYYASDVWSFGVTLYEL 1094
+ + Y SD+WS G+T E+
Sbjct 201 ACDENPDATYDYRSDIWSLGITAIEM 226
Score = 37.0 bits (84), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 42/191 (22%), Positives = 80/191 (42%), Gaps = 22/191 (12%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG--PENI----MVTEYVEH 692
+KV+D + + E L H ++A +G ++ P N +V E+
Sbjct 51 AAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGA 110
Query 693 GPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G + ++ +G+ + + +++ L++L ++H ++ G+N+LL
Sbjct 111 GSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTE------- 163
Query 752 SPFIKLSDPGVGLG---ALSREERVERIP-WLAPECLPGGANSLST---AMDKWGFGATL 804
+ +KL D GV + R P W+APE + N +T D W G T
Sbjct 164 NAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITA 223
Query 805 LEICFDGEAPL 815
+E+ +G PL
Sbjct 224 IEMA-EGAPPL 233
>sp|O80888|M3K17_ARATH Mitogen-activated protein kinase kinase
kinase 17 OS=Arabidopsis thaliana OX=3702 GN=MAPKKK17 PE=1
SV=1
Length=372
Score = 80.9 bits (198), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 65/215 (30%), Positives = 101/215 (47%), Gaps = 33/215 (15%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ-EIDILRTLYHEHI 959
R LG G V Y + E++AVK+ + HRS + Q E IL +L ++
Sbjct 7 RILGRGSTATV----YAAAGHNSDEILAVKSSEV-----HRSEFLQREAKILSSLSSPYV 57
Query 960 IKYKGC---CEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYL 1014
I Y+G E G L+MEY P G+L D + + +++ + + I +G+ Y+
Sbjct 58 IGYRGSETKRESNGVVMYNLLMEYAPYGTLTDAAAKDGGRVDETRVVKYTRDILKGLEYI 117
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF----WYAP 1070
H++ +H D+ NV++ KI DFG AK RV +SPV + AP
Sbjct 118 HSKGIVHCDVKGSNVVISEKGEAKIADFGCAK---------RVDPVFESPVMGTPAFMAP 168
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
E + K SD+W+ G T+ E++T SPP
Sbjct 169 EVARGEKQGKESDIWAVGCTMIEMVTG-----SPP 198
Score = 37.0 bits (84), Expect = 0.95, Method: Compositional matrix adjust.
Identities = 48/216 (22%), Positives = 82/216 (38%), Gaps = 32/216 (15%)
Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVT-----EYVEHGPLDVWLRRERGHVPMAWKMV 713
A ++S +S ++ G + N +V EY +G L ++ G V +
Sbjct 46 AKILSSLSSPYVIGYRGSETKRESNGVVMYNLLMEYAPYGTLTDAAAKDGGRVDETRVVK 105
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
+ + L Y+ +K +VH +V G N++++ G A K++D G R + V
Sbjct 106 YTRDILKGLEYIHSKGIVHCDVKGSNVVISEKGEA-------KIAD----FGCAKRVDPV 154
Query 774 ERIP------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--EH 825
P ++APE G + D W G T++E+ G P E
Sbjct 155 FESPVMGTPAFMAPEVARGEKQGKES--DIWAVGCTMIEM-VTGSPPWTKADSREDPVSV 211
Query 826 FYQRQHRLPEPSCPQL-----ATLTSQCLTYEPTQR 856
Y+ + P P L +CL E +R
Sbjct 212 LYRVGYSSETPELPCLLAEEAKDFLEKCLKREANER 247
>sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo
sapiens OX=9606 GN=GSK3A PE=1 SV=2
Length=483
Score = 82.0 bits (201), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 70/211 (33%), Positives = 104/211 (49%), Gaps = 33/211 (16%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I+ +G G FG V Y T E+VA+K + D ++R E+ I+R L H +I
Sbjct 122 IKVIGNGSFGVV----YQARLAETRELVAIKKVLQDKRFKNR-----ELQIMRKLDHCNI 172
Query 960 IKYKGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRH------SIGLAQLLLFAQQICE 1009
++ + GEK L LV+EYVP R + RH +I + + ++ Q+
Sbjct 173 VRLRYFFYSSGEKKDELYLNLVLEYVPETVYR--VARHFTKAKLTIPILYVKVYMYQLFR 230
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGH---EYYRVREDGDSPV 1065
+AY+H+Q HRD+ +N+L+D D V K+ DFG AK + G Y R
Sbjct 231 SLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR------- 283
Query 1066 FWYAPECLKEYKFYYAS-DVWSFGVTLYELL 1095
++ APE + Y +S DVWS G L ELL
Sbjct 284 YYRAPELIFGATDYTSSIDVWSAGCVLAELL 314
Score = 36.6 bits (83), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 31/128 (24%), Positives = 59/128 (46%), Gaps = 12/128 (9%)
Query 685 MVTEYVEHGPLDVW--LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+V EYV V + + +P+ + V QL +L+Y+ ++ + H ++ +N+L+
Sbjct 193 LVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLV 252
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWG 799
+ + +KL D G + E V I + APE + GA ++++D W
Sbjct 253 ------DPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELI-FGATDYTSSIDVWS 305
Query 800 FGATLLEI 807
G L E+
Sbjct 306 AGCVLAEL 313
>sp|Q9TXJ0|CMK1_CAEEL Calcium/calmodulin-dependent protein kinase
type 1 OS=Caenorhabditis elegans OX=6239 GN=cmk-1 PE=1 SV=1
Length=348
Score = 80.5 bits (197), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 65/215 (30%), Positives = 97/215 (45%), Gaps = 16/215 (7%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
PA + T+ K + + LG G F KV L + G+M AVK +
Sbjct 12 PAPNATIREKYDFRDV--LGTGAFSKVFLA---ESKSDAGQMYAVKCIDKKALKGKEESL 66
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLF 1003
+ EI +LR L H +I++ +++ + + LVME V G L D + + S
Sbjct 67 ENEIKVLRKLRHNNIVQLFDTYDEK--QFVYLVMELVTGGELFDRIVAKGSYTEQDASNL 124
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+Q+ E + ++H +HRDL N+L D D + I DFGL+K G V
Sbjct 125 IRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKTEDSG-----VMAT 179
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+ APE L++ + A DVWS GV Y LL
Sbjct 180 ACGTPGYVAPEVLQQKPYGKAVDVWSIGVIAYILL 214
>sp|P24100|CDKA1_ARATH Cyclin-dependent kinase A-1 OS=Arabidopsis
thaliana OX=3702 GN=CDKA-1 PE=1 SV=1
Length=294
Score = 79.7 bits (195), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 20/208 (10%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYH 956
+K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ + H
Sbjct 5 EKVEKIGEGTYGVV----YKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR--DYLPRHSIGLAQLLLFAQQICEGMAYL 1014
+I+K + EK L LV EY+ L + D P S L + + QI G+AY
Sbjct 61 SNIVKLQDVV--HSEKRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYC 118
Query 1015 HAQHYIHRDLAARNVLLD-NDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070
H+ +HRDL +N+L+D +K+ DFGLA+A +P + V WY AP
Sbjct 119 HSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEV------VTLWYRAP 172
Query 1071 EC-LKEYKFYYASDVWSFGVTLYELLTH 1097
E L + + D+WS G E+++
Sbjct 173 EILLGSHHYSTPVDIWSVGCIFAEMISQ 200
>sp|Q9SYA0|Y1150_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61500 OS=Arabidopsis thaliana OX=3702
GN=At1g61500 PE=2 SV=2
Length=804
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 83/284 (29%), Positives = 130/284 (46%), Gaps = 25/284 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V G+ +AVK L + G Q + + EI ++ L H ++++
Sbjct 497 LGQGGFGSVY-----KGKLQDGKEIAVKRLSSSSG-QGKEEFMNEIVLISKLQHRNLVRV 550
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017
GCC ++ EK L+ E++ SL +L R I + Q I G+ YLH
Sbjct 551 LGCCIEEEEK--LLIYEFMVNKSLDTFLFDSRKRLEIDWPKRFDIIQGIARGLLYLHHDS 608
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
IHRDL N+LLD KI DFGLA+ + +G EY + + +PE
Sbjct 609 RLRVIHRDLKVSNILLDEKMNPKISDFGLAR-MYQGTEYQDNTRRVVGTLGYMSPEYAWT 667
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
F SD++SFGV + E+++ S+ S + LI A + R +LL++
Sbjct 668 GMFSEKSDIYSFGVLMLEIISGEKISRFSYGVEGKTLIAYAWESWSEYRGIDLLDQ---- 723
Query 1135 PRPDKC-PCEVYHLMKN---CWETEASFRPTFENLIPILKTVHE 1174
D C P EV ++ C + + + RP L+ +L T +
Sbjct 724 DLADSCHPLEVGRCIQIGLLCVQHQPADRPNTLELLAMLTTTSD 767
>sp|Q38868|CDPK9_ARATH Calcium-dependent protein kinase 9 OS=Arabidopsis
thaliana OX=3702 GN=CPK9 PE=1 SV=1
Length=541
Score = 82.0 bits (201), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 67/209 (32%), Positives = 104/209 (50%), Gaps = 30/209 (14%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHE- 957
++LG G FG V+ C T + TG+ A K++ K + ++EI I++ L +
Sbjct 95 KELGRGQFG-VTYLC---TENSTGKKYACKSISKKKLVTKADKDDMRREIQIMQHLSGQP 150
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-------YLPRHSIGLAQLLLFAQQICEG 1010
+I+++KG ED EK++ LVME G L D Y R + + + ++ +IC
Sbjct 151 NIVEFKGAYED--EKAVNLVMELCAGGELFDRIIAKGHYTERAAASVCRQIVNVVKICHF 208
Query 1011 MAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
M LH RDL N LL D L+K DFGL+ + EG +V D ++
Sbjct 209 MGVLH------RDLKPENFLLSSKDEKALIKATDFGLSVFIEEG----KVYRDIVGSAYY 258
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096
APE L+ ++ D+WS G+ LY LL+
Sbjct 259 VAPEVLRR-RYGKEVDIWSAGIILYILLS 286
>sp|Q91ZN7|CHK1_RAT Serine/threonine-protein kinase Chk1 OS=Rattus
norvegicus OX=10116 GN=Chek1 PE=2 SV=1
Length=476
Score = 81.6 bits (200), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 67/199 (34%), Positives = 97/199 (49%), Gaps = 11/199 (6%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
++ LGEG +G+V L N T E VAVK + K+EI I + L HE++
Sbjct 12 VQTLGEGAYGEVQL----AVNRITEEAVAVKIVDMKRAIDCPENIKKEICINKMLNHENV 67
Query 960 IKYKGCCEDQGEKSLQ-LVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+K+ G + E ++Q L +EY G L D + P + F Q+ G+ YLH
Sbjct 68 VKFYG---HRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGI 124
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
HRD+ N+LLD +KI DFGLA V + R+ + + APE LK +
Sbjct 125 GITHRDIKPENLLLDERDNLKISDFGLA-TVFRHNNRERLLNKMCGTLPYVAPELLKRKE 183
Query 1078 FYYA-SDVWSFGVTLYELL 1095
F+ DVWS G+ L +L
Sbjct 184 FHAEPVDVWSCGIVLTAML 202
>sp|Q8BRK8|AAPK2_MOUSE 5'-AMP-activated protein kinase catalytic
subunit alpha-2 OS=Mus musculus OX=10090 GN=Prkaa2 PE=1 SV=3
Length=552
Score = 82.0 bits (201), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 73/201 (36%), Positives = 95/201 (47%), Gaps = 22/201 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957
LG G FGKV + + TG VAVK L + RS K+EI L+ H
Sbjct 22 LGVGTFGKVKI----GEHQLTGHKVAVKILNRQ---KIRSLDVVGKIKREIQNLKLFRHP 74
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016
HIIK + +VMEYV G L DY+ +H + + QQI + Y H
Sbjct 75 HIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHR 132
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE +
Sbjct 133 HMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 187
Query 1077 KFYYA--SDVWSFGVTLYELL 1095
+ Y D+WS GV LY LL
Sbjct 188 RLYAGPEVDIWSCGVILYALL 208
Score = 35.4 bits (80), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 62/262 (24%), Positives = 105/262 (40%), Gaps = 24/262 (9%)
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726
H H+ ++ V + MV EYV G L ++ + G V + QQ+ SA+ Y
Sbjct 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKH-GRVEEVEARRLFQQILSAVDYCH 131
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-----WLAP 781
+VH ++ N+LL A K++D GL + + R + AP
Sbjct 132 RHMVVHRDLKPENVLLDAQMNA-------KIAD--FGLSNMMSDGEFLRTSCGSPNYAAP 182
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQ 840
E + G + +D W G L + G P P+ + +P+
Sbjct 183 EVISGRLYA-GPEVDIWSCGVILYALLC-GTLPFDDEHVPTLFKKIRGGVFYIPDYLNRS 240
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+ATL L +P +R + + I R+ + +L L P+ P+ D V +K++
Sbjct 241 VATLLMHMLQVDPLKRATIKDI-REHEWFK-QDLPSYLF--PEDPSYDANVIDDEAVKEV 296
Query 901 RDLGEGHFGKV--SLYCYDPTN 920
+ E +V SLY DP +
Sbjct 297 CEKFECTESEVMNSLYSGDPQD 318
>sp|O54988|SLK_MOUSE STE20-like serine/threonine-protein kinase
OS=Mus musculus OX=10090 GN=Slk PE=1 SV=2
Length=1233
Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 61/205 (30%), Positives = 99/205 (48%), Gaps = 23/205 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I +LG+G FGKV Y N T + A K + + + EIDIL + H +I
Sbjct 37 IGELGDGAFGKV----YKAQNKETNVLAAAKVIDTK-SEEELEDYMVEIDILASCDHPNI 91
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQ 1017
+K E +L +++E+ G++ + + +Q+ + +Q E + YLH
Sbjct 92 VKLLDAF--YYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDN 149
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---FWYAPECL- 1073
IHRDL A N+L D +K+ DFG++ + R + DS + +W APE +
Sbjct 150 KIIHRDLKAGNILFTLDGDIKLADFGVS------AKNTRTIQRRDSFIGTPYWMAPEVVM 203
Query 1074 ----KEYKFYYASDVWSFGVTLYEL 1094
K+ + Y +DVWS G+TL E+
Sbjct 204 CETSKDRPYDYKADVWSLGITLIEM 228
Score = 40.4 bits (93), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 31/104 (30%), Positives = 44/104 (42%), Gaps = 14/104 (13%)
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG---ALS 768
VV +Q AL+YL + ++H ++ NIL G IKL+D GV +
Sbjct 133 QVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDG-------DIKLADFGVSAKNTRTIQ 185
Query 769 REERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808
R + P W+APE C D W G TL+E+
Sbjct 186 RRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMA 229
>sp|D7UPN3|RLK10_ORYSJ LysM domain receptor-like kinase 10 OS=Oryza
sativa subsp. japonica OX=39947 GN=RLK10 PE=2 SV=1
Length=605
Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 80/286 (28%), Positives = 124/286 (43%), Gaps = 33/286 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FG V + GE A+K + G Q + E+ +L ++H ++++
Sbjct 323 IGQGGFGSVYY------AELRGEKTAIKKM----GMQATQEFLAELKVLTHVHHLNLVRL 372
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH- 1018
G C E L LV E++ G+L +L R + A + A G+ YLH +H
Sbjct 373 IGYCV---ENCLFLVYEFIDNGNLSQHLQRTGYAPLSWATRVQIALDSARGLEYLH-EHV 428
Query 1019 ---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG--HEYYRVREDGDSPVFWYAPECL 1073
Y+HRD+ + N+LLD D KI DFGLAK G + R G F Y P
Sbjct 429 VPVYVHRDIKSANILLDKDFRAKIADFGLAKLTEVGSMSQSLSTRVAG---TFGYMPPEA 485
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR-------LTE 1126
+ + DV++FGV LYELL+ + E G+ L L E
Sbjct 486 RYGEVSPKVDVYAFGVVLYELLSAKQAIVRSSESVSESKGLVFLFEEALSAPNPTEALDE 545
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
L++ + P ++ L K+C E RPT +++ L +
Sbjct 546 LIDPSLQGDYPVDSALKIASLAKSCTHEEPGMRPTMRSVVVALMAL 591
>sp|Q09137|AAPK2_RAT 5'-AMP-activated protein kinase catalytic
subunit alpha-2 OS=Rattus norvegicus OX=10116 GN=Prkaa2 PE=1
SV=1
Length=552
Score = 82.0 bits (201), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 73/201 (36%), Positives = 95/201 (47%), Gaps = 22/201 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957
LG G FGKV + + TG VAVK L + RS K+EI L+ H
Sbjct 22 LGVGTFGKVKI----GEHQLTGHKVAVKILNRQ---KIRSLDVVGKIKREIQNLKLFRHP 74
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016
HIIK + +VMEYV G L DY+ +H + + QQI + Y H
Sbjct 75 HIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHR 132
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE +
Sbjct 133 HMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 187
Query 1077 KFYYA--SDVWSFGVTLYELL 1095
+ Y D+WS GV LY LL
Sbjct 188 RLYAGPEVDIWSCGVILYALL 208
Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 24/262 (9%)
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726
H H+ ++ V + MV EYV G L ++ + G V + QQ+ SA+ Y
Sbjct 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKH-GRVEEVEARRLFQQILSAVDYCH 131
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-----WLAP 781
+VH ++ N+LL A K++D GL + + R + AP
Sbjct 132 RHMVVHRDLKPENVLLDAQMNA-------KIAD--FGLSNMMSDGEFLRTSCGSPNYAAP 182
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQ 840
E + G + +D W G L + G P P+ + +PE
Sbjct 183 EVISGRLYA-GPEVDIWSCGVILYALLC-GTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS 240
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+ATL L +P +R + + I R+ + +L L P+ P+ D V +K++
Sbjct 241 IATLLMHMLQVDPLKRATIKDI-REHEWFK-QDLPSYLF--PEDPSYDANVIDDEAVKEV 296
Query 901 RDLGEGHFGKV--SLYCYDPTN 920
+ E +V SLY DP +
Sbjct 297 CEKFECTESEVMNSLYSGDPQD 318
>sp|Q8RWZ5|SD25_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase SD2-5 OS=Arabidopsis thaliana OX=3702
GN=SD25 PE=1 SV=1
Length=821
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 79/297 (27%), Positives = 136/297 (46%), Gaps = 55/297 (19%)
Query 903 LGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG V +GT G +AVK L+ Q + ++ E+ I+ +++H H+
Sbjct 499 LGQGGFGSVY--------EGTLPDGSRLAVKKLEGI--GQGKKEFRAEVSIIGSIHHLHL 548
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYL 1014
++ +G C + + L E++ GSL ++ R G L A +G+AYL
Sbjct 549 VRLRGFCAEGAHR--LLAYEFLSKGSLERWIFRKKDGDVLLDWDTRFNIALGTAKGLAYL 606
Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP--EGHEYYRVREDGDSPVFWYA 1069
H +H D+ N+LLD++ K+ DFGLAK + + H + +R + A
Sbjct 607 HEDCDARIVHCDIKPENILLDDNFNAKVSDFGLAKLMTREQSHVFTTMR----GTRGYLA 662
Query 1070 PECLKEYKFYYASDVWSFGVTLYELL---THCDSSQS------PPTKFL-----ELIGIA 1115
PE + Y SDV+S+G+ L EL+ + D S++ P F +L+ I
Sbjct 663 PEWITNYAISEKSDVYSYGMVLLELIGGRKNYDPSETSEKCHFPSFAFKKMEEGKLMDIV 722
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
G+M + +T+ ER+ R K C + + RP+ ++ +L+ V
Sbjct 723 DGKMKNVDVTD-----ERVQRAMKTALW-------CIQEDMQTRPSMSKVVQMLEGV 767
Score = 55.5 bits (132), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 53/185 (29%), Positives = 84/185 (45%), Gaps = 25/185 (14%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL-RRERGHVPMAW--K 711
F S++ + H HL + G C G ++ E++ G L+ W+ R++ G V + W +
Sbjct 533 FRAEVSIIGSIHHLHLVRLRGFCAEGAHRLLAYEFLSKGSLERWIFRKKDGDVLLDWDTR 592
Query 712 MVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+A A L+YL + +VH ++ NILL A K+SD G+ ++
Sbjct 593 FNIALGTAKGLAYLHEDCDARIVHCDIKPENILLDDNFNA-------KVSDFGLA-KLMT 644
Query 769 REE-------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
RE+ R R +LAPE + A +S D + +G LLE+ G S
Sbjct 645 REQSHVFTTMRGTR-GYLAPEWITNYA--ISEKSDVYSYGMVLLEL-IGGRKNYDPSETS 700
Query 822 EKEHF 826
EK HF
Sbjct 701 EKCHF 705
>sp|C0LGP2|MEE39_ARATH Probable LRR receptor-like serine/threonine-protein
kinase MEE39 OS=Arabidopsis thaliana OX=3702 GN=MEE39
PE=1 SV=1
Length=878
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 63/204 (31%), Positives = 102/204 (50%), Gaps = 15/204 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LGEG FG V Y +G+ E VAVK L + Q +K E+++L ++H +++
Sbjct 570 RPLGEGGFGVV----YHGDLNGS-EQVAVKLL-SQTSAQGYKEFKAEVELLLRVHHINLV 623
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHS---IGLAQLLLFAQQICEGMAYLHA 1016
G C++Q L+ EY+ G L +L +H + L A + G+ YLH
Sbjct 624 NLVGYCDEQDH--FALIYEYMSNGDLHQHLSGKHGGSVLNWGTRLQIAIEAALGLEYLHT 681
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+HRD+ + N+LLD + KI DFGL+++ G + +V + + PE
Sbjct 682 GCKPAMVHRDVKSTNILLDEEFKAKIADFGLSRSFQVGGDQSQVSTVVAGTLGYLDPEYY 741
Query 1074 KEYKFYYASDVWSFGVTLYELLTH 1097
+ SDV+SFG+ L E++T+
Sbjct 742 LTSELSEKSDVYSFGILLLEIITN 765
Score = 38.1 bits (87), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 53/201 (26%), Positives = 83/201 (41%), Gaps = 22/201 (11%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G G E +V +K+L + F L+ +V H +L + G C ++ EY
Sbjct 583 GDLNGSE-QVAVKLLSQTSAQGYKEFKAEVELLLRVHHINLVNLVGYCDEQDHFALIYEY 641
Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744
+ +G L L + G + W ++ +A + A L YL +VH +V NILL
Sbjct 642 MSNGDLHQHLSGKHGGSVLNWGTRLQIAIEAALGLEYLHTGCKPAMVHRDVKSTNILLDE 701
Query 745 LGLAEGTSPFIKLSDPGVGL-----GALSREERVE--RIPWLAPECLPGGANSLSTAMDK 797
A K++D G+ G S+ V + +L PE + LS D
Sbjct 702 EFKA-------KIADFGLSRSFQVGGDQSQVSTVVAGTLGYLDPEYYL--TSELSEKSDV 752
Query 798 WGFGATLLEICFDGEAPLQSR 818
+ FG LLEI + Q+R
Sbjct 753 YSFGILLLEIITNQRVIDQTR 773
>sp|Q8RXC8|RBK2_ARATH Receptor-like cytosolic serine/threonine-protein
kinase RBK2 OS=Arabidopsis thaliana OX=3702 GN=RBK2
PE=1 SV=1
Length=460
Score = 81.6 bits (200), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 56/179 (31%), Positives = 92/179 (51%), Gaps = 10/179 (6%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
G+++AVK L + + + E+ I+ + H + K+ GCC + G + LV PL
Sbjct 165 GKLIAVKRLTKGTPDEQTAEFLSELGIIAHVDHPNTAKFIGCCIEGG---MHLVFRLSPL 221
Query 984 GSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLV 1037
GSL L ++ + ++ A +G+ YLH + IHRD+ A N+LL D
Sbjct 222 GSLGSLLHGPSKYKLTWSRRYNVALGTADGLVYLHEGCQRRIIHRDIKADNILLTEDFQP 281
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+I DFGLAK +P+ ++ V + + ++APE +DV++FGV L EL+T
Sbjct 282 QICDFGLAKWLPKQLTHHNVSK-FEGTFGYFAPEYFMHGIVDEKTDVFAFGVLLLELIT 339
>sp|Q8S8S7|PUB34_ARATH U-box domain-containing protein 34 OS=Arabidopsis
thaliana OX=3702 GN=PUB34 PE=3 SV=1
Length=801
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 82/291 (28%), Positives = 138/291 (47%), Gaps = 35/291 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG +GKV Y + D T AVK ++ D P+ + + +E+++L L H H++
Sbjct 448 IGEGGYGKV----YQCSLDSTP--AAVKVVRLDT-PEKKQEFLKEVEVLSQLRHPHVVLL 500
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ-----QICEGMAYLHAQ 1017
G C + G LV EY+ GSL +Y+ H L F + ++ G+A+LH+
Sbjct 501 LGACPENG----CLVYEYLENGSLEEYI-FHRKNKPPLPWFIRFRVIFEVACGLAFLHSS 555
Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAV----PEGHEYYRVREDGDSPVFWYAP 1070
+HRDL N+LL+ + + KI D GLAK V P+ YR + + + P
Sbjct 556 KPEPIVHRDLKPGNILLNRNYVSKIADVGLAKLVTDVAPDNVTMYRNSVLAGT-LHYIDP 614
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E + SD+++FG+ + +LLT + P+ + + A + T LTE+L++
Sbjct 615 EYHRTGTIRPKSDLYAFGIIILQLLTARN-----PSGIVPAVENAVKKGT---LTEMLDK 666
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN-LIPILKTVHEKYQGQA 1180
P E+ + C E RP ++ +IP+LK + E +
Sbjct 667 SV-TDWPLAETEELARIGLKCAEFRCRDRPDLKSEVIPVLKRLVETANSKV 716
Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 45/183 (25%), Positives = 83/183 (45%), Gaps = 35/183 (19%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAW--K 711
F + ++SQ+ H H+ + G C PEN +V EY+E+G L+ ++ + P+ W +
Sbjct 482 FLKEVEVLSQLRHPHVVLLLGAC---PENGCLVYEYLENGSLEEYIFHRKNKPPLPWFIR 538
Query 712 MVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
V ++A L++L + +VH ++ NILL R ++ K++D VGL L
Sbjct 539 FRVIFEVACGLAFLHSSKPEPIVHRDLKPGNILLNRNYVS-------KIAD--VGLAKLV 589
Query 769 REERVERIPWLAPECLPGG----------ANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ + + L G ++ D + FG +L++ L +R
Sbjct 590 TDVAPDNVTMYRNSVLAGTLHYIDPEYHRTGTIRPKSDLYAFGIIILQL-------LTAR 642
Query 819 SPS 821
+PS
Sbjct 643 NPS 645
>sp|P20689|MYLK2_RAT Myosin light chain kinase 2, skeletal/cardiac
muscle OS=Rattus norvegicus OX=10116 GN=Mylk2 PE=1 SV=2
Length=610
Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 61/198 (31%), Positives = 99/198 (50%), Gaps = 15/198 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V C T TG +A K +K P+ + EI+++ L H ++I+
Sbjct 305 LGGGKFGAV-CTC---TERSTGLKLAAKVIKKQT-PKDKEMVLLEIEVMNQLNHRNLIQL 359
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020
E E + L MEY+ G L + + L ++ ++F +QIC+G+ ++H +
Sbjct 360 YSAIETSHE--IILFMEYIEGGELFERIVDEDYQLTEVDTMVFVRQICDGILFMHKMRVL 417
Query 1021 HRDLAARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
H DL N+L N LVKI DFGLA+ + +++ + +P F +PE + +
Sbjct 418 HLDLKPENILCVNTTGHLVKIIDFGLARRY---NPNEKLKVNFGTPEF-LSPEVVNYDQI 473
Query 1079 YYASDVWSFGVTLYELLT 1096
+D+WS GV Y LL+
Sbjct 474 SDKTDMWSLGVITYMLLS 491
Score = 35.4 bits (80), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 39/180 (22%), Positives = 74/180 (41%), Gaps = 24/180 (13%)
Query 632 DRGQELRVVLKVLD---PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+R L++ KV+ P ++ L E +M+Q++H +L ++ E I+ E
Sbjct 318 ERSTGLKLAAKVIKKQTPKDKEMVLLEIE---VMNQLNHRNLIQLYSAIETSHEIILFME 374
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
Y+E G L + E + MV +Q+ + ++ ++H ++ NIL
Sbjct 375 YIEGGELFERIVDEDYQLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNT--- 431
Query 749 EGTSPFIKLSDPGVGLGALSREERVERIP-------WLAPECLPGGANSLSTAMDKWGFG 801
T +K+ D G R E++ +L+PE + + +S D W G
Sbjct 432 --TGHLVKIID----FGLARRYNPNEKLKVNFGTPEFLSPEVV--NYDQISDKTDMWSLG 483
>sp|O70405|ULK1_MOUSE Serine/threonine-protein kinase ULK1 OS=Mus
musculus OX=10090 GN=Ulk1 PE=1 SV=1
Length=1051
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 60/180 (33%), Positives = 87/180 (48%), Gaps = 16/180 (9%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VAVK + + ++ +EI IL+ L HE+I+ E S+ LVMEY G L
Sbjct 43 VAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEM--ANSVYLVMEYCNGGDL 100
Query 987 RDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN---------DRL 1036
DYL ++ + LF QQI M LH++ IHRDL +N+LL N +
Sbjct 101 ADYLHTMRTLSEDTVRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIR 160
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
VKI DFG A+ + SP++ APE + + +D+WS G +Y+ LT
Sbjct 161 VKIADFGFARYL---QSNMMAATLCGSPMYM-APEVIMSQHYDGKADLWSIGTIVYQCLT 216
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 39/178 (22%), Positives = 76/178 (43%), Gaps = 9/178 (5%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
++ ++ H ++ ++ +V EY G L +L R ++ + QQ+A
Sbjct 66 ILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFL-QQIAG 124
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---- 776
A+ L +K ++H ++ +NILL+ G I++ G + +
Sbjct 125 AMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAATLCGS 184
Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833
++APE + + D W G T++ C G+AP Q+ SP + FY++ L
Sbjct 185 PMYMAPEVI--MSQHYDGKADLWSIG-TIVYQCLTGKAPFQASSPQDLRLFYEKNKTL 239
>sp|Q54HC6|ARKA_DICDI Ankyrin repeat-containing protein kinase
A OS=Dictyostelium discoideum OX=44689 GN=arkA PE=1 SV=1
Length=1460
Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 71/287 (25%), Positives = 128/287 (45%), Gaps = 23/287 (8%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
L+ +G G GKV Y G +VA+K LK+ R + +E +L +L
Sbjct 1112 LEYTEKIGSGASGKVFKGIY------RGRVVAIKVLKSADDEMTREDFLKEFGVLASLES 1165
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016
I+ G E + LVMEY GS+ + ++ + F QQ+ G+ LH
Sbjct 1166 HTIVGLYGVVL---EPKICLVMEYCSNGSIYHSIRKNPPSWERFFSFVQQMLAGINALHQ 1222
Query 1017 Q--HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+HRD+ N L++++ VK+ DFGL++ E ++ + G S + APE +
Sbjct 1223 STPQVLHRDIKTLNFLVNHNNKVKVADFGLSRFNTESNQETLNKTRGTS--VYCAPEVFE 1280
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
++ SD++S G+ ++E++ +C + E ++ L+ +R+
Sbjct 1281 GKEYNERSDMYSMGIVMWEIV-YCVVYGCYMIPYQEY----NKMFNAFQVALLVNSSKRV 1335
Query 1135 PRPDKCPCEVYHLMKN----CWETEASFRPTFENLIPILKTVHEKYQ 1177
RP P V ++K+ W+ + S RPT + L ++Y+
Sbjct 1336 LRP-TIPIGVPQVLKDLIYCLWDHDVSSRPTATEAMTALAVCEKEYK 1381
>sp|Q54G43|SHKE_DICDI Dual specificity protein kinase shkE OS=Dictyostelium
discoideum OX=44689 GN=shkE PE=3 SV=1
Length=710
Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 70/267 (26%), Positives = 118/267 (44%), Gaps = 32/267 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G +GKV Y T G V V + + +S +K E++I++ ++H +++
Sbjct 243 LGGGAYGKV----YKATCRGKKVAVKVPKKQTLSESELKS-FKNEVEIMKQIFHPNVVLC 297
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ-HYIH 1021
G C G+ + + L L L + + G+ +LH + IH
Sbjct 298 LGACTKPGKVMIVSELMQTDLEKLIHSSEVEPPPLYERMKMCLDAALGINWLHGICNIIH 357
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP---VFWYAPECLKEYKF 1078
RDL N+++ D+ VKIGDFG ++ + G D P + APE + +++F
Sbjct 358 RDLKLANLMISKDKTVKIGDFGFSQVIKTG----TTLSDQKGPKGTALYMAPEVMMKHEF 413
Query 1079 YYASDVWSFGVTLYELLTHCDS---SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+DV+SFG+ LYE+ T C+ S F + I + R P
Sbjct 414 NEKADVYSFGLILYEMAT-CEELFPEYSEIDPFYDAI---------------CNKKLRPP 457
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTF 1162
PD P + L++ CW+ + + RP+F
Sbjct 458 IPDSFPKSLKTLIQKCWDHDPNKRPSF 484
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 52/232 (22%), Positives = 105/232 (45%), Gaps = 31/232 (13%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
+F +M Q+ H ++ G C + + ++V+E ++ + E P+ +M
Sbjct 278 SFKNEVEIMKQIFHPNVVLCLGACTKPGKVMIVSELMQTDLEKLIHSSEVEPPPLYERMK 337
Query 714 VAQQLASALSYLENKNLVHG--NVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGAL 767
+ A +++L HG N+ R++ LA L +++ + +K+ D G + G
Sbjct 338 MCLDAALGINWL------HGICNIIHRDLKLANLMISKDKT--VKIGDFGFSQVIKTGTT 389
Query 768 SREERVER--IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP--SEK 823
+++ + ++APE + + + D + FG L E+ A + P SE
Sbjct 390 LSDQKGPKGTALYMAPEVM--MKHEFNEKADVYSFGLILYEM-----ATCEELFPEYSEI 442
Query 824 EHFY----QRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ FY ++ R P P S P+ L TL +C ++P +RPSF + + + +
Sbjct 443 DPFYDAICNKKLRPPIPDSFPKSLKTLIQKCWDHDPNKRPSFNEVTQRMNEV 494
>sp|Q6BVA0|IPL1_DEBHA Spindle assembly checkpoint kinase OS=Debaryomyces
hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394
/ JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=IPL1 PE=3
SV=2
Length=412
Score = 81.3 bits (199), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 57/195 (29%), Positives = 88/195 (45%), Gaps = 7/195 (4%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G GKV YC G + V A K + +++EI+I L H I +
Sbjct 154 LGKGKLGKV--YCVKHKTSGYIAALKVMAKKDLIDLKLEKNFRREIEIQSNLIHPKISRL 211
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G D K++ L++EY G L +L + A + Q+ + YLH +H IH
Sbjct 212 YGFFYDH--KNVYLILEYSIHGELYHHLKVQRRFNDATASHYIYQVALALDYLHTKHIIH 269
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RD+ N+LL D +K+ DFG + R+ G + + PE ++ + Y
Sbjct 270 RDIKPENILLSTDNCIKLSDFGWSVKSSPSSSTKRLTICG--TLDYLPPEMIESNEHDYT 327
Query 1082 SDVWSFGVTLYELLT 1096
D+WS G+ YE L
Sbjct 328 VDIWSLGILCYEFLV 342
Score = 40.0 bits (92), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 49/218 (22%), Positives = 85/218 (39%), Gaps = 23/218 (11%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F + S + H ++ ++G ++ EY HG L L+ +R +
Sbjct 193 FRREIEIQSNLIHPKISRLYGFFYDHKNVYLILEYSIHGELYHHLKVQRRFNDATASHYI 252
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-----VGLGALSR 769
Q +A AL YL K+++H ++ NILL+ T IKLSD G + R
Sbjct 253 YQ-VALALDYLHTKHIIHRDIKPENILLS-------TDNCIKLSDFGWSVKSSPSSSTKR 304
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
+ +L PE + +N +D W G E G+ P + +K Y+R
Sbjct 305 LTICGTLDYLPPEMIE--SNEHDYTVDIWSLGILCYEFLV-GKPPFEE---IDKNSTYKR 358
Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
++P + L + L P +R + ++
Sbjct 359 IAKVDLKIPSFLSSEATDLILRLLQKSPKKRITLAEVM 396
>sp|Q04735|CDK16_MOUSE Cyclin-dependent kinase 16 OS=Mus musculus
OX=10090 GN=Cdk16 PE=1 SV=1
Length=496
Score = 81.6 bits (200), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 60/202 (30%), Positives = 94/202 (47%), Gaps = 15/202 (7%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
K+ LGEG + V Y + T +VA+K ++ + +E+ +L+ L H +
Sbjct 167 KLDKLGEGTYATV----YKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHAN 222
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHA 1016
I+ EKSL LV EY+ L+ YL + I + + LF Q+ G+AY H
Sbjct 223 IVTLHDII--HTEKSLTLVFEYLD-KDLKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHR 279
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--CLK 1074
Q +HRDL +N+L++ +K+ DFGLA+A + Y + WY P L
Sbjct 280 QKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTY----SNEVVTLWYRPPDILLG 335
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ D+W G YE+ T
Sbjct 336 STDYSTQIDMWGVGCIFYEMAT 357
Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 61/271 (23%), Positives = 106/271 (39%), Gaps = 57/271 (21%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
R ++LS++ F +++ +L LG+GT VY+G+ K+ D
Sbjct 150 RRVSLSEIGFGKLET--YIKLDKLGEGTYATVYKGK-----------SKLTDN------- 189
Query 632 DRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
V LK + H + A A E SL+ + H ++ +H + +V EY
Sbjct 190 ------LVALKEIRLEHEEGAPCTAIRE-VSLLKDLKHANIVTLHDIIHTEKSLTLVFEY 242
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
++ L +L + M + QL L+Y + ++H ++ +N+L+ G
Sbjct 243 LDKD-LKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERG--- 298
Query 750 GTSPFIKLSDPGVGLGALSREERVERIP-----------WLAPECLPGGANSLSTAMDKW 798
+KL+D G+ R + IP W P + G+ ST +D W
Sbjct 299 ----ELKLADFGLA--------RAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMW 346
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
G G E+ G + E+ HF R
Sbjct 347 GVGCIFYEMA-TGRPLFPGSTVEEQLHFIFR 376
>sp|Q54MV2|MRKB_DICDI Probable serine/threonine-protein kinase
MARK-B OS=Dictyostelium discoideum OX=44689 GN=mrkB PE=3 SV=1
Length=715
Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 62/198 (31%), Positives = 98/198 (49%), Gaps = 11/198 (6%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+ +G G KV + TN TG+ A+K K + R ++EI IL+ L H++II
Sbjct 69 KTIGSGTSSKVKI----GTNILTGKQYAIKITKPK-RIKERKEIEREISILKRLKHDNII 123
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ + + L++E V G L DY+ R + + F +Q+ G+ Y H+
Sbjct 124 QLHDAIYEDDVGRICLILELVSGGELFDYIVARGRLSEKEGRKFFRQMLCGLIYCHSNMV 183
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
HRDL N+L+D D +KI DFG + + G+ + SPV+ PE L E ++
Sbjct 184 CHRDLKLENLLVDEDGNLKISDFGYSNIIKPGN---LLSTFCGSPVYA-PPEILLEKRYN 239
Query 1080 -YASDVWSFGVTLYELLT 1096
D+WS GV LY ++T
Sbjct 240 GNEVDIWSMGVILYAMVT 257
>sp|Q8GWJ7|CRK19_ARATH Cysteine-rich receptor-like protein kinase
19 OS=Arabidopsis thaliana OX=3702 GN=CRK19 PE=1 SV=2
Length=645
Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 84/289 (29%), Positives = 132/289 (46%), Gaps = 34/289 (12%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I LG+G FG+V Y T +G VAVK L G Q ++ E+ ++ L H ++
Sbjct 329 INKLGQGGFGEV----YKGTL-SSGLQVAVKRLSKTSG-QGEKEFENEVVVVAKLQHRNL 382
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL----AQLLLFAQQICEGMAYLH 1015
+K G C + EK L V E+VP SL +L ++ + + I G+ YLH
Sbjct 383 VKLLGYCLEGEEKIL--VYEFVPNKSLDHFLFDSTMKMKLDWTRRYKIIGGIARGILYLH 440
Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
IHRDL A N+LLD+D KI DFG+A+ R + + +PE
Sbjct 441 QDSRLTIIHRDLKAGNILLDDDMNPKIADFGMARIFGMDQTEAMTRRVVGT-YGYMSPEY 499
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL--RL------ 1124
+F SDV+SFGV + E+++ +S L + + G + RL
Sbjct 500 AMYGQFSMKSDVYSFGVLVLEIISGMKNSS------LYQMDESVGNLVTYTWRLWSNGSP 553
Query 1125 TELLE--RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+EL++ G+ + C H+ C + +A RPT +++ +L T
Sbjct 554 SELVDPSFGDNYQTSEITRC--IHIALLCVQEDAEDRPTMSSIVQMLTT 600
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/227 (24%), Positives = 96/227 (42%), Gaps = 45/227 (20%)
Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651
++ LGQG VY+G L SG L+V +K L +
Sbjct 329 INKLGQGGFGEVYKGTL---SSG----------------------LQVAVKRLSKTSGQG 363
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW- 710
F +++++ H +L + G C+ G E I+V E+V + LD +L + + W
Sbjct 364 EKEFENEVVVVAKLQHRNLVKLLGYCLEGEEKILVYEFVPNKSLDHFLFDSTMKMKLDWT 423
Query 711 -KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--L 764
+ + +A + YL + ++H ++ NIL L + +P K++D G+
Sbjct 424 RRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNIL-----LDDDMNP--KIADFGMARIF 476
Query 765 GALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
G E R+ +++PE G S+ + D + FG +LEI
Sbjct 477 GMDQTEAMTRRVVGTYGYMSPEYAMYGQFSMKS--DVYSFGVLVLEI 521
>sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo
sapiens OX=9606 GN=CHEK1 PE=1 SV=2
Length=476
Score = 81.6 bits (200), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 68/200 (34%), Positives = 99/200 (50%), Gaps = 13/200 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
++ LGEG +G+V L N T E VAVK + K+EI I + L HE++
Sbjct 12 VQTLGEGAYGEVQL----AVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENV 67
Query 960 IKYKGCCEDQGEKSLQ-LVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHA 1016
+K+ G + E ++Q L +EY G L D + IG+ + F Q+ G+ YLH
Sbjct 68 VKFYG---HRREGNIQYLFLEYCSGGELFDRI-EPDIGMPEPDAQRFFHQLMAGVVYLHG 123
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
HRD+ N+LLD +KI DFGLA V + R+ + + APE LK
Sbjct 124 IGITHRDIKPENLLLDERDNLKISDFGLA-TVFRYNNRERLLNKMCGTLPYVAPELLKRR 182
Query 1077 KFYYA-SDVWSFGVTLYELL 1095
+F+ DVWS G+ L +L
Sbjct 183 EFHAEPVDVWSCGIVLTAML 202
>sp|O75385|ULK1_HUMAN Serine/threonine-protein kinase ULK1 OS=Homo
sapiens OX=9606 GN=ULK1 PE=1 SV=2
Length=1050
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 60/180 (33%), Positives = 86/180 (48%), Gaps = 16/180 (9%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VAVK + + ++ +EI IL+ L HE+I+ E S+ LVMEY G L
Sbjct 43 VAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEM--ANSVYLVMEYCNGGDL 100
Query 987 RDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR---------L 1036
DYL ++ + LF QQI M LH++ IHRDL +N+LL N
Sbjct 101 ADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIR 160
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
VKI DFG A+ + SP++ APE + + +D+WS G +Y+ LT
Sbjct 161 VKIADFGFARYL---QSNMMAATLCGSPMYM-APEVIMSQHYDGKADLWSIGTIVYQCLT 216
Score = 46.6 bits (109), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 43/178 (24%), Positives = 81/178 (46%), Gaps = 9/178 (5%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
++ ++ H ++ ++ +V EY G L +L R ++ + QQ+A
Sbjct 66 ILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFL-QQIAG 124
Query 721 ALSYLENKNLVHGNVCGRNILLARLG--LAEGTSPFIKLSDPGVG--LGALSREERVERI 776
A+ L +K ++H ++ +NILL+ A S +K++D G L + +
Sbjct 125 AMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGS 184
Query 777 P-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833
P ++APE + + D W G T++ C G+AP Q+ SP + FY++ L
Sbjct 185 PMYMAPEVI--MSQHYDGKADLWSIG-TIVYQCLTGKAPFQASSPQDLRLFYEKNKTL 239
>sp|Q5PU49|KPCD_CANLF Protein kinase C delta type OS=Canis lupus
familiaris OX=9615 GN=PRKCD PE=2 SV=1
Length=674
Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 71/226 (31%), Positives = 105/226 (46%), Gaps = 34/226 (15%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
D +FHK LG+G FGKV L G E A+KALK D +
Sbjct 345 DNFIFHKV-------LGKGSFGKVLLV----ELKGKKEFFAIKALKKDVVLI-------D 386
Query 948 IDILRTLYHEHIIKYKG--------CCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLA 998
D+ T+ + ++ C Q + L VME++ G L ++ + L
Sbjct 387 DDVECTMVEKRVLALAWENPFLTHLFCTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELY 446
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
+ +A +I G+ +LH + I+RDL NV+LD D +KI DFG+ K G + +
Sbjct 447 RATFYAAEIVCGLQFLHNKGIIYRDLKLDNVMLDQDGHIKIADFGMCKENIFGEK--QAS 504
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
+P + APE L+ K+ ++ D WSFGV LYE+L QSP
Sbjct 505 TFCGTPDY-IAPEILQGLKYSFSVDWWSFGVLLYEMLI----GQSP 545
Score = 42.7 bits (99), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 42/183 (23%), Positives = 82/183 (45%), Gaps = 19/183 (10%)
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
V E++ G L ++ +++G + A ++ L +L NK +++ ++ N++L
Sbjct 422 FFVMEFLNGGDL-MYHIQDKGRFELYRATFYAAEIVCGLQFLHNKGIIYRDLKLDNVMLD 480
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWG 799
+ G IK++D G+ + E++ ++APE L G S S +D W
Sbjct 481 QDG-------HIKIADFGMCKENIFGEKQASTFCGTPDYIAPEILQGLKYSFS--VDWWS 531
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859
FG L E+ G++P E E F R+ P P+ T S+ + + +R +
Sbjct 532 FGVLLYEMLI-GQSPFH--GDDEDELF--ESIRVDTPHYPRWITKESKDILEKLLERDTT 586
Query 860 RTI 862
+ +
Sbjct 587 KRL 589
>sp|Q60680|IKKA_MOUSE Inhibitor of nuclear factor kappa-B kinase
subunit alpha OS=Mus musculus OX=10090 GN=Chuk PE=1 SV=1
Length=745
Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 63/206 (31%), Positives = 96/206 (47%), Gaps = 24/206 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG VSLY + + +A+K+ + + ++R W EI I++ L H +++K
Sbjct 21 LGTGGFGNVSLYQHRELDLK----IAIKSCRLELSSKNRERWCHEIQIMKKLDHANVVK- 75
Query 963 KGCCEDQGEKSLQ------LVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMA 1012
C+ E + L MEY G LR L P + GL +Q+L I G+
Sbjct 76 --ACDVPEELNFLINDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIR 133
Query 1013 YLHAQHYIHRDLAARNVLLDN---DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH IHRDL N++L + + KI D G AK V +G + + + A
Sbjct 134 YLHENKIIHRDLKPENIVLQDVGGKTIHKIIDLGYAKDVDQG----SLCTSFVGTLQYLA 189
Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095
PE + + D WSFG ++E +
Sbjct 190 PELFENKPYTATVDYWSFGTMVFECI 215
>sp|O55092|SLK_CAVPO STE20-like serine/threonine-protein kinase
OS=Cavia porcellus OX=10141 GN=SLK PE=1 SV=1
Length=1231
Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 61/205 (30%), Positives = 99/205 (48%), Gaps = 23/205 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I +LG+G FGKV Y N T + A K + + + EIDIL + H +I
Sbjct 37 IGELGDGAFGKV----YKAQNKETNVLAAAKVIDTKS-EEELEDYMVEIDILASCDHPNI 91
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQ 1017
+K E +L +++E+ G++ + + +Q+ + +Q E + YLH
Sbjct 92 VKLLDAF--YYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDN 149
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---FWYAPECL- 1073
IHRDL A N+L D +K+ DFG++ + R + DS + +W APE +
Sbjct 150 KIIHRDLKAGNILFTLDGDIKLADFGVS------AKNTRTIQRRDSFIGTPYWMAPEVVM 203
Query 1074 ----KEYKFYYASDVWSFGVTLYEL 1094
K+ + Y +DVWS G+TL E+
Sbjct 204 CETSKDRPYDYKADVWSLGITLIEM 228
Score = 40.8 bits (94), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 31/103 (30%), Positives = 44/103 (43%), Gaps = 14/103 (14%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG---ALSR 769
VV +Q AL+YL + ++H ++ NIL G IKL+D GV + R
Sbjct 134 VVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDG-------DIKLADFGVSAKNTRTIQR 186
Query 770 EERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808
+ P W+APE C D W G TL+E+
Sbjct 187 RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMA 229
>sp|Q63686|CDK16_RAT Cyclin-dependent kinase 16 OS=Rattus norvegicus
OX=10116 GN=Cdk16 PE=1 SV=2
Length=496
Score = 81.6 bits (200), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 60/202 (30%), Positives = 94/202 (47%), Gaps = 15/202 (7%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
K+ LGEG + V Y + T +VA+K ++ + +E+ +L+ L H +
Sbjct 167 KLDKLGEGTYATV----YKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHAN 222
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHA 1016
I+ EKSL LV EY+ L+ YL + I + + LF Q+ G+AY H
Sbjct 223 IVTLHDII--HTEKSLTLVFEYLD-KDLKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHR 279
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--CLK 1074
Q +HRDL +N+L++ +K+ DFGLA+A + Y + WY P L
Sbjct 280 QKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTY----SNEVVTLWYRPPDILLG 335
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ D+W G YE+ T
Sbjct 336 STDYSTQIDMWGVGCIFYEMAT 357
Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 61/271 (23%), Positives = 106/271 (39%), Gaps = 57/271 (21%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
R ++LS++ F +++ +L LG+GT VY+G+ K+ D
Sbjct 150 RRVSLSEIGFGKLET--YIKLDKLGEGTYATVYKGK-----------SKLTDN------- 189
Query 632 DRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
V LK + H + A A E SL+ + H ++ +H + +V EY
Sbjct 190 ------LVALKEIRLEHEEGAPCTAIRE-VSLLKDLKHANIVTLHDIIHTEKSLTLVFEY 242
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
++ L +L + M + QL L+Y + ++H ++ +N+L+ G
Sbjct 243 LDKD-LKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERG--- 298
Query 750 GTSPFIKLSDPGVGLGALSREERVERIP-----------WLAPECLPGGANSLSTAMDKW 798
+KL+D G+ R + IP W P + G+ ST +D W
Sbjct 299 ----ELKLADFGLA--------RAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMW 346
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
G G E+ G + E+ HF R
Sbjct 347 GVGCIFYEMA-TGRPLFPGSTVEEQLHFIFR 376
>sp|P87248|ATG1_COLLN Serine/threonine-protein kinase ATG1 OS=Colletotrichum
lindemuthianum OX=290576 GN=ATG1 PE=3 SV=1
Length=675
Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 78/316 (25%), Positives = 130/316 (41%), Gaps = 73/316 (23%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHII 960
++G+G F +V Y + + VA+K+++ + R EI IL+TL H HI+
Sbjct 30 EIGKGSFAQV----YSGHHKNSKAAVAIKSVEMGRLNNKLRENLYGEIQILKTLRHPHIV 85
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSI-----------------GLAQL 1000
C E + LVMEY LG L ++ RH GL ++
Sbjct 86 ALHDCVESATH--INLVMEYCELGDLSFFIKKRDRHGTNAATEDMARKYPVTPGSGLHEV 143
Query 1001 LL--FAQQICEGMAYLHAQHYIHRDLAARNVLL-----------------DNDRLV---- 1037
+ F QQ+ + +L ++Y+HRD+ +N+LL ND L+
Sbjct 144 VTRHFLQQLASALKFLREKNYVHRDVKPQNLLLLPSPGFRKENSRPILTASNDSLIPNAG 203
Query 1038 -------KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
K+ DFG A+ +P + SP++ APE L+ ++ +D+WS G
Sbjct 204 LASLPMLKLADFGFARVLPSTSLADTL---CGSPLYM-APEILRYERYDAKADLWSVGTV 259
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
LYE++T PP + A+ + +LR E E + P+ ++ L+
Sbjct 260 LYEMIT-----GRPPFR-------ARNHVELLRKIEATEDKVKYPKDAVVSKDLVKLIGK 307
Query 1151 CWETEASFRPTFENLI 1166
R FE+
Sbjct 308 LLTRNPVERMRFEDFF 323
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 68/263 (26%), Positives = 102/263 (39%), Gaps = 58/263 (22%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGH------VP 707
Y ++ + H H+ +H CV +I +V EY E G L ++++ H
Sbjct 69 LYGEIQILKTLRHPHIVALHD-CVESATHINLVMEYCELGDLSFFIKKRDRHGTNAATED 127
Query 708 MAWKMVVA--------------QQLASALSYLENKNLVHGNVCGRNILL----------- 742
MA K V QQLASAL +L KN VH +V +N+LL
Sbjct 128 MARKYPVTPGSGLHEVVTRHFLQQLASALKFLREKNYVHRDVKPQNLLLLPSPGFRKENS 187
Query 743 ------------ARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIP-WLAPECLPGG 787
GLA + P +KL+D G L + S + + P ++APE L
Sbjct 188 RPILTASNDSLIPNAGLA--SLPMLKLADFGFARVLPSTSLADTLCGSPLYMAPEIL--R 243
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE---KEHFYQRQHRLPEPSC--PQLA 842
D W G L E+ G P ++R+ E K + + + P+ + L
Sbjct 244 YERYDAKADLWSVGTVLYEM-ITGRPPFRARNHVELLRKIEATEDKVKYPKDAVVSKDLV 302
Query 843 TLTSQCLTYEPTQRPSFRTILRD 865
L + LT P +R F D
Sbjct 303 KLIGKLLTRNPVERMRFEDFFND 325
>sp|Q9UIK4|DAPK2_HUMAN Death-associated protein kinase 2 OS=Homo
sapiens OX=9606 GN=DAPK2 PE=1 SV=1
Length=370
Score = 80.5 bits (197), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 66/227 (29%), Positives = 110/227 (48%), Gaps = 26/227 (11%)
Query 884 SPASDPTVFHKRYLKKIRDLGE----GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
SP +P F ++ ++ D+GE G F V C + + TG A K +K
Sbjct 8 SPNMEP--FKQQKVEDFYDIGEELGSGQFAIVK-KCREKS---TGLEYAAKFIKKRQSRA 61
Query 940 HRSG-----WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RH 993
R G ++E+ ILR + H ++I E++ + + L++E V G L D+L +
Sbjct 62 SRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTD--VVLILELVSGGELFDFLAQKE 119
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL----VKIGDFGLAKAVP 1049
S+ + F +QI +G+ YLH + H DL N++L + + +K+ DFGLA +
Sbjct 120 SLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIE 179
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+G E+ + +P F APE + +D+WS GV Y LL+
Sbjct 180 DGVEFKNI---FGTPEF-VAPEIVNYEPLGLEADMWSIGVITYILLS 222
Score = 35.4 bits (80), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 42/171 (25%), Positives = 71/171 (42%), Gaps = 18/171 (11%)
Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQ 717
S++ QV H ++ +H V + +++ E V G L D ++E A + +Q
Sbjct 75 VSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFI--KQ 132
Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE--- 774
+ ++YL K + H ++ NI+L + P IKL D G+ A E+ VE
Sbjct 133 ILDGVNYLHTKKIAHFDLKPENIMLLDKNIP---IPHIKLIDFGL---AHEIEDGVEFKN 186
Query 775 ---RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
++APE + L D W G + I G +P + E
Sbjct 187 IFGTPEFVAPEIV--NYEPLGLEADMWSIGV-ITYILLSGASPFLGDTKQE 234
>sp|Q9WUT3|KS6A2_MOUSE Ribosomal protein S6 kinase alpha-2 OS=Mus
musculus OX=10090 GN=Rps6ka2 PE=1 SV=1
Length=733
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 62/212 (29%), Positives = 108/212 (51%), Gaps = 13/212 (6%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWK 945
+DP+ F + ++ LG+G +GKV L T G++ A+K LK A + R K
Sbjct 54 ADPSQF-----ELLKVLGQGSYGKVFL-VRKVTGSDAGQLYAMKVLKKATLKVRDRVRSK 107
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ-LLLFA 1004
E DIL + H I+K + +G+ L L+++++ G L L + + + + +
Sbjct 108 MERDILAEVNHPFIVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYL 165
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
++ + +LH I+RDL N+LLD + +KI DFGL+K E ++ +
Sbjct 166 AELALALDHLHGLGIIYRDLKPENILLDEEGHIKITDFGLSK---EATDHDKRAYSFCGT 222
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+ + APE + ++D WSFGV ++E+LT
Sbjct 223 IEYMAPEVVNRRGHTQSADWWSFGVLMFEMLT 254
Score = 63.9 bits (154), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 62/185 (34%), Positives = 86/185 (46%), Gaps = 29/185 (16%)
Query 946 QEIDIL-RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLL 1001
+EI+IL R H +II K +D K + LVME + G L D + R S A +
Sbjct 455 EEIEILLRYGQHPNIITLKDVYDDG--KYVYLVMELMRGGELLDRILRQRCFSEREASDV 512
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRV 1057
L+ I M YLH+Q +HRDL N+L N ++I DFG AK +
Sbjct 513 LYT--IARTMDYLHSQGVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLRA------- 563
Query 1058 REDG--DSPVF---WYAPECLKEYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKF 1108
E+G +P + + APE LK + A DVWS G+ LY +L + P +
Sbjct 564 -ENGLLMTPCYTANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPDDTPEEI 622
Query 1109 LELIG 1113
L IG
Sbjct 623 LARIG 627
>sp|Q0UY20|ATG1_PHANO Serine/threonine-protein kinase atg1 OS=Phaeosphaeria
nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)
OX=321614 GN=ATG1 PE=3 SV=2
Length=972
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 75/321 (23%), Positives = 134/321 (42%), Gaps = 78/321 (24%)
Query 897 LKKIRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRT 953
K++ +G+G F +V ++ T + VA+K++ + + + EI ILR+
Sbjct 30 FKRMDHIGKGSFAEVYRGIHIVPNTQQEKRQSVAIKSVNMNKLNKKLKDNLVSEISILRS 89
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI------------------ 995
L+H HI+ C E + ++ME+ LG L ++ + +
Sbjct 90 LHHPHIVSLIDCHETPSR--MHIIMEFCELGDLSAFIKKRADLVNHPQTQRMIEKYPNPA 147
Query 996 --GLAQLLL--FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR---------------- 1035
GL ++++ FA+Q+ + +L +++YIHRDL +N+LL+
Sbjct 148 VGGLNEVIVRHFAKQMASALEFLRSKNYIHRDLKPQNLLLNPSSVYYSQSGTLERMPLAA 207
Query 1036 ---------------LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
++KI DFG A+ +P + E + APE L+ K+
Sbjct 208 DASSLLPATGIESLPMLKIADFGFARILPTTS----LAETLCGSPLYMAPEILRYEKYDA 263
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
+D+WS G L+E++ C PP + A + +LR E ER + + P+
Sbjct 264 KADLWSVGTVLFEMM--C---ARPPFR-------ANNHVELLRKIE--ERKDHIRFPEGI 309
Query 1141 PCEVYHLMKNCWETEASFRPT 1161
C MKN +PT
Sbjct 310 VCS--RAMKNLIRALLKRKPT 328
Score = 41.2 bits (95), Expect = 0.073, Method: Compositional matrix adjust.
Identities = 71/334 (21%), Positives = 125/334 (37%), Gaps = 85/334 (25%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
++ H+G+G+ VY G +VP + + V +K ++ + +
Sbjct 32 RMDHIGKGSFAEVYRGIH------------------IVPNTQQEKRQSVAIKSVNMNKLN 73
Query 651 IALA--FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHV- 706
L S++ + H H+ + C P + ++ E+ E G L ++++ V
Sbjct 74 KKLKDNLVSEISILRSLHHPHIVSLID-CHETPSRMHIIMEFCELGDLSAFIKKRADLVN 132
Query 707 -PMAWKMV------------------VAQQLASALSYLENKNLVHGNVCGRNIL------ 741
P +M+ A+Q+ASAL +L +KN +H ++ +N+L
Sbjct 133 HPQTQRMIEKYPNPAVGGLNEVIVRHFAKQMASALEFLRSKNYIHRDLKPQNLLLNPSSV 192
Query 742 -------LARLGLAEGTS-----------PFIKLSDPGVG--LGALSREERVERIP-WLA 780
L R+ LA S P +K++D G L S E + P ++A
Sbjct 193 YYSQSGTLERMPLAADASSLLPATGIESLPMLKIADFGFARILPTTSLAETLCGSPLYMA 252
Query 781 PECLPGGANSLSTAMDKWGFGATLLEIC-------FDGEAPLQSRSPSEKEHFYQRQHRL 833
PE L D W G L E+ + L + K+H R
Sbjct 253 PEIL--RYEKYDAKADLWSVGTVLFEMMCARPPFRANNHVELLRKIEERKDHI-----RF 305
Query 834 PEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRD 865
PE C + + L L +PT+R S+ + D
Sbjct 306 PEGIVCSRAMKNLIRALLKRKPTERMSYDSFFSD 339
>sp|O64556|Y2923_ARATH Putative leucine-rich repeat receptor-like
serine/threonine-protein kinase At2g19230 OS=Arabidopsis
thaliana OX=3702 GN=At2g19230 PE=1 SV=3
Length=877
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/203 (30%), Positives = 102/203 (50%), Gaps = 18/203 (9%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LG+G FGKV GE VA+K L ++ ++ E+++L ++H+++I
Sbjct 573 RVLGQGGFGKVYYGVL------RGEQVAIKMLSKSSAQGYKE-FRAEVELLLRVHHKNLI 625
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLH-- 1015
G C + + + L+ EY+ G+L DYL + + + L + +G+ YLH
Sbjct 626 ALIGYCHEGDQ--MALIYEYIGNGTLGDYLSGKNSSILSWEERLQISLDAAQGLEYLHNG 683
Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECL 1073
+HRD+ N+L++ KI DFGL+++ EG +V + + + PE
Sbjct 684 CKPPIVHRDVKPTNILINEKLQAKIADFGLSRSFTLEGDS--QVSTEVAGTIGYLDPEHY 741
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
+F SDV+SFGV L E++T
Sbjct 742 SMQQFSEKSDVYSFGVVLLEVIT 764
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 63/254 (25%), Positives = 102/254 (40%), Gaps = 54/254 (21%)
Query 588 EITQLSH-----LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
EI ++++ LGQG VY G LR E +V +K
Sbjct 563 EIVEITNNFERVLGQGGFGKVYYGVLRGE--------------------------QVAIK 596
Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+L S F L+ +V H +L + G C G + ++ EY+ +G L +L +
Sbjct 597 MLSKSSAQGYKEFRAEVELLLRVHHKNLIALIGYCHEGDQMALIYEYIGNGTLGDYLSGK 656
Query 703 RGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ ++W ++ ++ A L YL N +VH +V NIL+ A K+
Sbjct 657 NSSI-LSWEERLQISLDAAQGLEYLHNGCKPPIVHRDVKPTNILINEKLQA-------KI 708
Query 758 SDPGVGLG-ALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
+D G+ L + +V I +L PE S D + FG LLE+
Sbjct 709 ADFGLSRSFTLEGDSQVSTEVAGTIGYLDPEHY--SMQQFSEKSDVYSFGVVLLEVI--T 764
Query 812 EAPLQSRSPSEKEH 825
P+ SRS +E+
Sbjct 765 GQPVISRSRTEENR 778
>sp|Q97PA9|STKP_STRPN Serine/threonine-protein kinase StkP OS=Streptococcus
pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
OX=170187 GN=stkP PE=1 SV=1
Length=659
Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 63/209 (30%), Positives = 99/209 (47%), Gaps = 11/209 (5%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEI 948
+F RY + ++ +G G V L D DG E VAVK L+ + P + +++E
Sbjct 7 IFAGRY-RIVKQIGRGGMADVYL-AKDLILDG--EEVAVKVLRTNYQTDPIAVARFQREA 62
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQI 1007
+ L H HI++ E+ G++ L MEYV L+ Y+ H + + + QI
Sbjct 63 RAMADLDHPHIVRITDIGEEDGQQ--YLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQI 120
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
M H + +HRDL +N+LL D K+ DFG+A A E G V +
Sbjct 121 LLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVAFAETSLTQTNSMLGS--VHY 178
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+PE + K SD+++ G+ YE+LT
Sbjct 179 LSPEQARGSKATVQSDIYAMGIIFYEMLT 207
Score = 35.0 bits (79), Expect = 5.3, Method: Compositional matrix adjust.
Identities = 52/222 (23%), Positives = 96/222 (43%), Gaps = 39/222 (18%)
Query 639 VVLKVLDPSHHD--IALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +KVL ++ IA+A F A M+ + H H+ + + + + EYV L
Sbjct 39 VAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDL 98
Query 696 DVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
+++ H P++ + V Q+ A+ + +VH ++ +NILL G A
Sbjct 99 KRYIKE---HYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTA----- 150
Query 754 FIKLSDPGVGLG----ALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLE-- 806
K++D G+ + +L++ + + +L+PE G ++ + D + G E
Sbjct 151 --KVTDFGIAVAFAETSLTQTNSMLGSVHYLSPEQARGSKATVQS--DIYAMGIIFYEML 206
Query 807 ---ICFDGEAPLQSRSPSEKEHFYQRQHRLP-----EPSCPQ 840
I +DG++ + +HF Q LP PS PQ
Sbjct 207 TGHIPYDGDSAVT----IALQHF---QKPLPSVIAENPSVPQ 241
>sp|Q3ZDQ4|ATG1_PODAS Serine/threonine-protein kinase ATG1 OS=Podospora
anserina OX=2587412 GN=ATG1 PE=2 SV=1
Length=941
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 76/318 (24%), Positives = 130/318 (41%), Gaps = 75/318 (24%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHI 959
+++G+G F +V Y + TG +VA+K+++ + + + EI IL+TL H HI
Sbjct 30 KEIGKGSFAQV----YSGRHKVTGALVAIKSVELSRLNKKLKENLYGEIKILKTLRHPHI 85
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSL--------------------RDYLPRHSIGLAQ 999
+ C E + L+MEY LG L R Y H+ GL +
Sbjct 86 VALHDCVESATH--INLIMEYCELGDLSLFIKKREKLITHSATRDIARRYPIEHNQGLHE 143
Query 1000 LLL--FAQQICEGMAYLHAQHYIHRDLAARNVLL-------------------DNDRLV- 1037
++ F +Q+ + +L +++HRD+ +N+LL D L+
Sbjct 144 VITRHFLKQLASALKFLREGNFVHRDVKPQNLLLLPSPLFRETHHSAKQILSASYDSLMP 203
Query 1038 ----------KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
K+ DFG A+ +P + E + APE L+ ++ +D+WS
Sbjct 204 AAGLPSLPMLKLADFGFARVLPSTS----LAETLCGSPLYMAPEILRYERYDAKADLWSV 259
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
G LYE+ T PP + A + +LR E E + PR E+ L
Sbjct 260 GTVLYEMATG-----RPPFR-------AGNHVELLRKIEAAEDQVKFPRESVVSPELKSL 307
Query 1148 MKNCWETEASFRPTFENL 1165
++ + R +F +
Sbjct 308 VRALLKRNPVERISFADF 325
Score = 47.8 bits (112), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 74/319 (23%), Positives = 122/319 (38%), Gaps = 82/319 (26%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
+G+G+ VY GR +V G+ V +K ++ S + L
Sbjct 32 IGKGSFAQVYSGRHKVTGA------------------------LVAIKSVELSRLNKKLK 67
Query 655 --FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWK 711
Y ++ + H H+ +H CV +I ++ EY E G L +++++ + +
Sbjct 68 ENLYGEIKILKTLRHPHIVALHD-CVESATHINLIMEYCELGDLSLFIKKREKLITHSAT 126
Query 712 MVVA--------------------QQLASALSYLENKNLVHGNVCGRNILL--------- 742
+A +QLASAL +L N VH +V +N+LL
Sbjct 127 RDIARRYPIEHNQGLHEVITRHFLKQLASALKFLREGNFVHRDVKPQNLLLLPSPLFRET 186
Query 743 ---ARLGLAEG-----------TSPFIKLSDPGVG--LGALSREERVERIP-WLAPECLP 785
A+ L+ + P +KL+D G L + S E + P ++APE L
Sbjct 187 HHSAKQILSASYDSLMPAAGLPSLPMLKLADFGFARVLPSTSLAETLCGSPLYMAPEIL- 245
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE---KEHFYQRQHRLPEPSC--PQ 840
D W G L E+ G P ++ + E K + Q + P S P+
Sbjct 246 -RYERYDAKADLWSVGTVLYEMA-TGRPPFRAGNHVELLRKIEAAEDQVKFPRESVVSPE 303
Query 841 LATLTSQCLTYEPTQRPSF 859
L +L L P +R SF
Sbjct 304 LKSLVRALLKRNPVERISF 322
>sp|Q8DNS0|STKP_STRR6 Serine/threonine-protein kinase StkP OS=Streptococcus
pneumoniae (strain ATCC BAA-255 / R6) OX=171101
GN=stkP PE=1 SV=1
Length=659
Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 63/209 (30%), Positives = 99/209 (47%), Gaps = 11/209 (5%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEI 948
+F RY + ++ +G G V L D DG E VAVK L+ + P + +++E
Sbjct 7 IFAGRY-RIVKQIGRGGMADVYL-AKDLILDG--EEVAVKVLRTNYQTDPIAVARFQREA 62
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQI 1007
+ L H HI++ E+ G++ L MEYV L+ Y+ H + + + QI
Sbjct 63 RAMADLDHPHIVRITDIGEEDGQQ--YLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQI 120
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
M H + +HRDL +N+LL D K+ DFG+A A E G V +
Sbjct 121 LLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVAFAETSLTQTNSMLGS--VHY 178
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+PE + K SD+++ G+ YE+LT
Sbjct 179 LSPEQARGSKATVQSDIYAMGIIFYEMLT 207
>sp|Q04J43|STKP_STRP2 Serine/threonine-protein kinase StkP OS=Streptococcus
pneumoniae serotype 2 (strain D39 / NCTC 7466)
OX=373153 GN=stkP PE=1 SV=1
Length=659
Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 63/209 (30%), Positives = 99/209 (47%), Gaps = 11/209 (5%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEI 948
+F RY + ++ +G G V L D DG E VAVK L+ + P + +++E
Sbjct 7 IFAGRY-RIVKQIGRGGMADVYL-AKDLILDG--EEVAVKVLRTNYQTDPIAVARFQREA 62
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQI 1007
+ L H HI++ E+ G++ L MEYV L+ Y+ H + + + QI
Sbjct 63 RAMADLDHPHIVRITDIGEEDGQQ--YLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQI 120
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
M H + +HRDL +N+LL D K+ DFG+A A E G V +
Sbjct 121 LLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVAFAETSLTQTNSMLGS--VHY 178
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+PE + K SD+++ G+ YE+LT
Sbjct 179 LSPEQARGSKATVQSDIYAMGIIFYEMLT 207
>sp|Q7TSC3|NEK5_MOUSE Serine/threonine-protein kinase Nek5 OS=Mus
musculus OX=10090 GN=Nek5 PE=2 SV=1
Length=627
Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 55/201 (27%), Positives = 98/201 (49%), Gaps = 16/201 (8%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I+ +GEG FGKV Y + +K + + + K E+ +L + H +I
Sbjct 7 IKIIGEGTFGKV----YLAKDKSESSHCVIKEISL---TKEKEASKNEVILLARMEHPNI 59
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA 1016
+ + ++ G L +VMEY G L + R Q+L + QI G+ ++H
Sbjct 60 VTFFSSFQENGR--LFIVMEYCDGGDLMQRIQRQRGVMFSEDQILCWFVQISLGLKHIHD 117
Query 1017 QHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ +HRD+ ++N+ L + +V K+GDFG A+ + + E + +P ++ +PE +
Sbjct 118 RKILHRDIKSQNIFLSKNGMVAKLGDFGTARTLNDSMELAQTC--AGTP-YYLSPEICQN 174
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
+ +D+WS G LYEL T
Sbjct 175 RPYNNKTDIWSLGCVLYELCT 195
Score = 40.8 bits (94), Expect = 0.084, Method: Compositional matrix adjust.
Identities = 53/254 (21%), Positives = 103/254 (41%), Gaps = 42/254 (17%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETAS-----LMSQVSHTHLAFVHGVCVRGPENI 684
+D+ + V+K +I+L + AS L++++ H ++
Sbjct 21 AKDKSESSHCVIK-------EISLTKEKEASKNEVILLARMEHPNIVTFFSSFQENGRLF 73
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILL 742
+V EY + G L ++R+RG V + ++ Q++ L ++ ++ ++H ++ +NI L
Sbjct 74 IVMEYCDGGDLMQRIQRQRG-VMFSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFL 132
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP----WLAPECLPGGANSLSTAMDKW 798
++ G+ KL D G E + +L+PE + T D W
Sbjct 133 SKNGMV------AKLGDFGTARTLNDSMELAQTCAGTPYYLSPEICQNRPYNNKT--DIW 184
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE----PSCP----QLATLTSQCLT 850
G L E+C + P E +F+ ++ + P P L +L Q
Sbjct 185 SLGCVLYELC-------TLKHPFESNNFHHLVLKICQGRVAPISPHFSRDLQSLIPQLFR 237
Query 851 YEPTQRPSFRTILR 864
P RPS ++L+
Sbjct 238 VSPQDRPSVTSLLK 251
>sp|Q0WVM4|Y2239_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At2g23950 OS=Arabidopsis thaliana OX=3702
GN=At2g23950 PE=1 SV=1
Length=634
Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 65/198 (33%), Positives = 93/198 (47%), Gaps = 13/198 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + G G +VAVK LK G S ++ E++++ H ++++
Sbjct 305 LGAGGFGNVYRGKF-----GDGTVVAVKRLKDVNGTSGNSQFRTELEMISLAVHRNLLRL 359
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ---H 1018
G C E+ LV Y+ GS+ L + ++ A G+ YLH Q
Sbjct 360 IGYCASSSER--LLVYPYMSNGSVASRLKAKPALDWNTRKKIAIGAARGLFYLHEQCDPK 417
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ A N+LLD +GDFGLAK + HE V V APE L +
Sbjct 418 IIHRDVKAANILLDEYFEAVVGDFGLAKLL--NHEDSHVTTAVRGTVGHIAPEYLSTGQS 475
Query 1079 YYASDVWSFGVTLYELLT 1096
+DV+ FG+ L EL+T
Sbjct 476 SEKTDVFGFGILLLELIT 493
>sp|Q9FII5|TDR_ARATH Leucine-rich repeat receptor-like protein
kinase TDR OS=Arabidopsis thaliana OX=3702 GN=TDR PE=1 SV=1
Length=1041
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/188 (32%), Positives = 91/188 (48%), Gaps = 20/188 (11%)
Query 923 TGEMVAVKAL---KADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLV 977
GE++AVK L + G R SG E+D+L + H +I++ GCC ++ L+
Sbjct 740 NGEIIAVKKLWGKNKENGKIRRRKSGVLAEVDVLGNVRHRNIVRLLGCCTNR--DCTMLL 797
Query 978 MEYVPLGSLRDYL---PRHSIGLAQ---LLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028
EY+P GSL D L + A+ L A + +G+ YLH +HRDL N
Sbjct 798 YEYMPNGSLDDLLHGGDKTMTAAAEWTALYQIAIGVAQGICYLHHDCDPVIVHRDLKPSN 857
Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
+LLD D ++ DFG+AK + V + APE + SD++S+G
Sbjct 858 ILLDADFEARVADFGVAKLIQTDESMSVVA----GSYGYIAPEYAYTLQVDKKSDIYSYG 913
Query 1089 VTLYELLT 1096
V L E++T
Sbjct 914 VILLEIIT 921
>sp|O22476|BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 OS=Arabidopsis
thaliana OX=3702 GN=BRI1 PE=1 SV=1
Length=1196
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 78/293 (27%), Positives = 131/293 (45%), Gaps = 27/293 (9%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
FH L +G G FG V G VA+K L G R + E++ +
Sbjct 883 FHNDSL-----IGSGGFGDVYKAILK-----DGSAVAIKKLIHVSGQGDRE-FMAEMETI 931
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHS---IGLAQLLLFAQQ 1006
+ H +++ G C+ E+ LV E++ GSL D L P+ + + + A
Sbjct 932 GKIKHRNLVPLLGYCKVGDER--LLVYEFMKYGSLEDVLHDPKKAGVKLNWSTRRKIAIG 989
Query 1007 ICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
G+A+LH + H IHRD+ + NVLLD + ++ DFG+A+ + + V +
Sbjct 990 SARGLAFLHHNCSPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGT 1049
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
P + PE + ++ DV+S+GV L ELLT + SP L+G + Q LR
Sbjct 1050 PG-YVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKRPTDSPDFGDNNLVGWVK-QHAKLR 1107
Query 1124 LTELLERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILKTVH 1173
++++ + E + E+ +K C + A RPT ++ + K +
Sbjct 1108 ISDVFDP-ELMKEDPALEIELLQHLKVAVACLDDRAWRRPTMVQVMAMFKEIQ 1159
>sp|G5ECH7|CDK5_CAEEL Cyclin-dependent-like kinase 5 OS=Caenorhabditis
elegans OX=6239 GN=cdk-5 PE=1 SV=1
Length=292
Score = 79.0 bits (193), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 24/205 (12%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957
K+ +GEG +G V + N +GE+VA+K ++ D + S +EI ILR L H
Sbjct 6 KMEKIGEGTYGTV----FKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHR 61
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVP------LGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011
++++ E L LV EY SL Y+ + A+ L+ Q+ G+
Sbjct 62 NVVRLYDVV--HSENKLTLVFEYCDQDLKKFFDSLNGYMDAQT---ARSLML--QLLRGL 114
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-AP 1070
++ HA H +HRDL +N+L++ + +K+ DFGLA+A + + WY P
Sbjct 115 SFCHAHHVLHRDLKPQNLLINTNGTLKLADFGLARAFGVPVRCF----SAEVVTLWYRPP 170
Query 1071 ECLKEYKFYYAS-DVWSFGVTLYEL 1094
+ L K Y S D+WS G E+
Sbjct 171 DVLFGAKLYNTSIDMWSAGCIFAEI 195
>sp|Q9SHI2|Y1723_ARATH Leucine-rich repeat receptor-like serine/threonine-protein
kinase At1g17230 OS=Arabidopsis thaliana
OX=3702 GN=At1g17230 PE=1 SV=2
Length=1101
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 73/219 (33%), Positives = 98/219 (45%), Gaps = 28/219 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
LG G G V Y G GE++AVK L + G + ++ EI L + H +I+K
Sbjct 805 LGRGACGTV----YKAEMSG-GEVIAVKKLNSRGEGASSDNSFRAEISTLGKIRHRNIVK 859
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-------FAQQICEGMAYL 1014
G C Q S L+ EY+ GSL + L R G LL A EG+ YL
Sbjct 860 LYGFCYHQ--NSNLLLYEYMSKGSLGEQLQR---GEKNCLLDWNARYRIALGAAEGLCYL 914
Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
H +HRD+ + N+LLD +GDFGLAK + Y + + APE
Sbjct 915 HHDCRPQIVHRDIKSNNILLDERFQAHVGDFGLAKLID--LSYSKSMSAVAGSYGYIAPE 972
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
K D++SFGV L EL+T PP + LE
Sbjct 973 YAYTMKVTEKCDIYSFGVVLLELITG-----KPPVQPLE 1006
Score = 43.1 bits (100), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 43/173 (25%), Positives = 75/173 (43%), Gaps = 20/173 (12%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--K 711
+F S + ++ H ++ ++G C N+++ EY+ G L L+R + + W +
Sbjct 841 SFRAEISTLGKIRHRNIVKLYGFCYHQNSNLLLYEYMSKGSLGEQLQRGEKNCLLDWNAR 900
Query 712 MVVAQQLASALSYLENK---NLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGAL 767
+A A L YL + +VH ++ NILL R G KL D L
Sbjct 901 YRIALGAAEGLCYLHHDCRPQIVHRDIKSNNILLDERFQAHVGDFGLAKLID-------L 953
Query 768 SREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
S + + + ++APE ++ D + FG LLE+ G+ P+Q
Sbjct 954 SYSKSMSAVAGSYGYIAPEY--AYTMKVTEKCDIYSFGVVLLEL-ITGKPPVQ 1003
>sp|Q28948|AAPK2_PIG 5'-AMP-activated protein kinase catalytic
subunit alpha-2 OS=Sus scrofa OX=9823 GN=PRKAA2 PE=2 SV=2
Length=552
Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 73/201 (36%), Positives = 95/201 (47%), Gaps = 22/201 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957
LG G FGKV + + TG VAVK L + RS K+EI L+ H
Sbjct 22 LGVGTFGKVKI----GEHQLTGHKVAVKILNRQ---KIRSLDVVGKIKREIQNLKLFRHP 74
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016
HIIK + +VMEYV G L DY+ +H + + QQI + Y H
Sbjct 75 HIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE +
Sbjct 133 HMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 187
Query 1077 KFYYA--SDVWSFGVTLYELL 1095
+ Y D+WS GV LY LL
Sbjct 188 RLYAGPEVDIWSCGVILYALL 208
Score = 36.6 bits (83), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 24/262 (9%)
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726
H H+ ++ V + MV EYV G L ++ + G V + QQ+ SA+ Y
Sbjct 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKH-GRVEEMEARRLFQQILSAVDYCH 131
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-----WLAP 781
+VH ++ N+LL A K++D GL + + R + AP
Sbjct 132 RHMVVHRDLKPENVLLDAQMNA-------KIAD--FGLSNMMSDGEFLRTSCGSPNYAAP 182
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQ 840
E + G + +D W G L + G P P+ + +PE
Sbjct 183 EVISGRLYA-GPEVDIWSCGVILYALLC-GTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS 240
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+ATL L +P +R + + I R+ + +L L P+ P+ D V +K++
Sbjct 241 VATLLMHMLQVDPLKRATIKDI-REHEWFK-QDLPSYLF--PEDPSYDANVIDDEAVKEV 296
Query 901 RDLGEGHFGKV--SLYCYDPTN 920
+ E +V SLY DP +
Sbjct 297 CEKFECTESEVMNSLYSGDPQD 318
>sp|P54646|AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic
subunit alpha-2 OS=Homo sapiens OX=9606 GN=PRKAA2 PE=1 SV=2
Length=552
Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 73/201 (36%), Positives = 95/201 (47%), Gaps = 22/201 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957
LG G FGKV + + TG VAVK L + RS K+EI L+ H
Sbjct 22 LGVGTFGKVKI----GEHQLTGHKVAVKILNRQ---KIRSLDVVGKIKREIQNLKLFRHP 74
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016
HIIK + +VMEYV G L DY+ +H + + QQI + Y H
Sbjct 75 HIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE +
Sbjct 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 187
Query 1077 KFYYA--SDVWSFGVTLYELL 1095
+ Y D+WS GV LY LL
Sbjct 188 RLYAGPEVDIWSCGVILYALL 208
Score = 36.2 bits (82), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 24/262 (9%)
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726
H H+ ++ V + MV EYV G L ++ + G V + QQ+ SA+ Y
Sbjct 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKH-GRVEEMEARRLFQQILSAVDYCH 131
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-----WLAP 781
+VH ++ N+LL A K++D GL + + R + AP
Sbjct 132 RHMVVHRDLKPENVLLDAHMNA-------KIAD--FGLSNMMSDGEFLRTSCGSPNYAAP 182
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQ 840
E + G + +D W G L + G P P+ + +PE
Sbjct 183 EVISGRLYA-GPEVDIWSCGVILYALLC-GTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS 240
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+ATL L +P +R + + I R+ + +L L P+ P+ D V +K++
Sbjct 241 VATLLMHMLQVDPLKRATIKDI-REHEWFK-QDLPSYLF--PEDPSYDANVIDDEAVKEV 296
Query 901 RDLGEGHFGKV--SLYCYDPTN 920
+ E +V SLY DP +
Sbjct 297 CEKFECTESEVMNSLYSGDPQD 318
>sp|P34112|CDK1_DICDI Cyclin-dependent kinase 1 OS=Dictyostelium
discoideum OX=44689 GN=cdk1 PE=2 SV=1
Length=296
Score = 79.0 bits (193), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 64/202 (32%), Positives = 97/202 (48%), Gaps = 15/202 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+K+ LGEG +GKV Y TG MVA+K ++ + + + EI +L+ + H
Sbjct 11 QKLEKLGEGTYGKV----YKAKEKATGRMVALKKIRLEDDGVPSTALR-EISLLKEVPHP 65
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLHA 1016
+++ Q L LV EY+ L+ Y+ QL+ + Q+ +G+AY H
Sbjct 66 NVVSLFDVLHCQNR--LYLVFEYLD-QDLKKYMDSVPALCPQLIKSYLYQLLKGLAYSHG 122
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075
+HRDL +N+L+D +K+ DFGLA+AV Y + WY APE L
Sbjct 123 HRILHRDLKPQNLLIDRQGALKLADFGLARAVSIPVRVYT----HEIVTLWYRAPEVLLG 178
Query 1076 YKFYYA-SDVWSFGVTLYELLT 1096
K Y D+WS G E+L
Sbjct 179 SKSYSVPVDMWSVGCIFGEMLN 200
Score = 36.2 bits (82), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 66/309 (21%), Positives = 111/309 (36%), Gaps = 73/309 (24%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+L LG+GT VY+ + + G V LK +
Sbjct 12 KLEKLGEGTYGKVYKAKEKATGR------------------------MVALKKIRLEDDG 47
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
+ SL+ +V H ++ + V +V EY LD L++ VP
Sbjct 48 VPSTALREISLLKEVPHPNVVSLFDVLHCQNRLYLVFEY-----LDQDLKKYMDSVPALC 102
Query 711 KMVVAQ---QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VG 763
++ QL L+Y ++H ++ +N+L+ R G +KL+D G V
Sbjct 103 PQLIKSYLYQLLKGLAYSHGHRILHRDLKPQNLLIDRQGA-------LKLADFGLARAVS 155
Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGEAPLQS- 817
+ + + + APE L G+ S S +D W G E+ F G+ +
Sbjct 156 IPVRVYTHEIVTLWYRAPEVLL-GSKSYSVPVDMWSVGCIFGEMLNKKPLFSGDCEIDQI 214
Query 818 -----RSPSEKEHFYQRQHRLPE-----------------PSCPQLA-TLTSQCLTYEPT 854
+ + + +LPE P C LA L ++ L YEP+
Sbjct 215 FRIFRVLGTPDDSIWPGVTKLPEYVSTFPNWPGQPYNKIFPRCEPLALDLIAKMLQYEPS 274
Query 855 QRPSFRTIL 863
+R S + L
Sbjct 275 KRISAKEAL 283
>sp|Q4WVG0|PKCA_ASPFU Protein kinase C OS=Aspergillus fumigatus
(strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) OX=330879
GN=pkcA PE=1 SV=1
Length=1106
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/198 (30%), Positives = 91/198 (46%), Gaps = 14/198 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH-----RSGWKQEIDILRTLYHE 957
LG+G+FGKV L T ++ A+K LK + ++ K+ I H
Sbjct 787 LGKGNFGKVML----AETKSTKKLYAIKVLKKEFIIENDEVESTKSEKRVFLIANKERHP 842
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
++ C Q E + VMEY+ G L ++ R GL + +A ++ + Y H
Sbjct 843 FLLNLHACF--QTETRVYFVMEYISGGDLMLHIQRGQFGLKRAQFYAAEVLLALKYFHEN 900
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
I+RDL N+LL D +KI D+GL K E Y + APE L + K
Sbjct 901 GVIYRDLKLDNILLTLDGHIKIADYGLCK---ENMWYGSTTSTFCGTPEFMAPEILLDKK 957
Query 1078 FYYASDVWSFGVTLYELL 1095
+ A D W+FGV +Y++L
Sbjct 958 YGRAVDWWAFGVLIYQML 975
>sp|Q9ZRF9|RPK1_ARATH Probable LRR receptor-like serine/threonine-protein
kinase RPK1 OS=Arabidopsis thaliana OX=3702 GN=RPK1
PE=1 SV=1
Length=540
Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 73/288 (25%), Positives = 120/288 (42%), Gaps = 21/288 (7%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
Y +G G FG PTN + ++V + D + EI L +
Sbjct 260 YFSNSNCIGHGGFGSTYKAEVSPTNVFAVKRLSVGRFQGD------QQFHAEISALEMVR 313
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMA 1012
H +++ G + E + L+ Y+ G+L+D++ S I L A + ++
Sbjct 314 HPNLVMLIGYHASETE--MFLIYNYLSGGNLQDFIKERSKAAIEWKVLHKIALDVARALS 371
Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068
YLH Q +HRD+ N+LLDN+ + DFGL+K + + G + F Y
Sbjct 372 YLHEQCSPKVLHRDIKPSNILLDNNYNAYLSDFGLSKLLGTSQSHVTT---GVAGTFGYV 428
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
APE + +DV+S+G+ L EL++ D S S ++ A ++ +
Sbjct 429 APEYAMTCRVSEKADVYSYGIVLLELISDKRALDPSFSSHENGFNIVSWAHMMLSQGKAK 488
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
E+ G P EV HL C S RPT + + +LK +
Sbjct 489 EVFTTGLWETGPPDDLVEVLHLALKCTVDSLSIRPTMKQAVRLLKRIQ 536
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 59/248 (24%), Positives = 95/248 (38%), Gaps = 37/248 (15%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV- 713
F+ S + V H +L + G E ++ Y+ G L +++ ER + WK++
Sbjct 302 FHAEISALEMVRHPNLVMLIGYHASETEMFLIYNYLSGGNLQDFIK-ERSKAAIEWKVLH 360
Query 714 -VAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLG 765
+A +A ALSYL + ++H ++ NILL A G S + S V G
Sbjct 361 KIALDVARALSYLHEQCSPKVLHRDIKPSNILLDNNYNAYLSDFGLSKLLGTSQSHVTTG 420
Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-- 823
++APE +S D + +G LLE+ D A S S E
Sbjct 421 VAGT------FGYVAPEY--AMTCRVSEKADVYSYGIVLLELISDKRALDPSFSSHENGF 472
Query 824 -----EHFYQRQHRL------------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
H Q + P ++ L +C + RP+ + +R L
Sbjct 473 NIVSWAHMMLSQGKAKEVFTTGLWETGPPDDLVEVLHLALKCTVDSLSIRPTMKQAVRLL 532
Query 867 TRLQPHNL 874
R+QP L
Sbjct 533 KRIQPSRL 540
>sp|Q00536|CDK16_HUMAN Cyclin-dependent kinase 16 OS=Homo sapiens
OX=9606 GN=CDK16 PE=1 SV=1
Length=496
Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/202 (30%), Positives = 94/202 (47%), Gaps = 15/202 (7%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
K+ LGEG + V Y + T +VA+K ++ + +E+ +L+ L H +
Sbjct 167 KLDKLGEGTYATV----YKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHAN 222
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHA 1016
I+ EKSL LV EY+ L+ YL + I + + LF Q+ G+AY H
Sbjct 223 IVTLHDII--HTEKSLTLVFEYLD-KDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHR 279
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--CLK 1074
Q +HRDL +N+L++ +K+ DFGLA+A + Y + WY P L
Sbjct 280 QKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTY----SNEVVTLWYRPPDILLG 335
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ D+W G YE+ T
Sbjct 336 STDYSTQIDMWGVGCIFYEMAT 357
Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 61/271 (23%), Positives = 106/271 (39%), Gaps = 57/271 (21%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
R ++LS++ F +++ +L LG+GT VY+G+ K+ D
Sbjct 150 RRVSLSEIGFGKLET--YIKLDKLGEGTYATVYKGK-----------SKLTDN------- 189
Query 632 DRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
V LK + H + A A E SL+ + H ++ +H + +V EY
Sbjct 190 ------LVALKEIRLEHEEGAPCTAIRE-VSLLKDLKHANIVTLHDIIHTEKSLTLVFEY 242
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
++ L +L + M + QL L+Y + ++H ++ +N+L+ G
Sbjct 243 LDKD-LKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERG--- 298
Query 750 GTSPFIKLSDPGVGLGALSREERVERIP-----------WLAPECLPGGANSLSTAMDKW 798
+KL+D G+ R + IP W P + G+ ST +D W
Sbjct 299 ----ELKLADFGLA--------RAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMW 346
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
G G E+ G + E+ HF R
Sbjct 347 GVGCIFYEMA-TGRPLFPGSTVEEQLHFIFR 376
>sp|A0A0U1RPR8|GUC2D_MOUSE Guanylate cyclase D OS=Mus musculus
OX=10090 GN=Gucy2d PE=2 SV=1
Length=1117
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 75/266 (28%), Positives = 120/266 (45%), Gaps = 25/266 (9%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
GE V +K +A P R + LR + HE++ + G G ++ V+E+
Sbjct 577 GEWVWLKKFEAGVAPDLRPSSLSFLRKLREMRHENVTAFLGLFVGPGVSAM--VLEHCAR 634
Query 984 GSLRDYLPRHSIGL-----AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
GSL D L ++ L A LLL + G+ YLH + + H L +RN ++D ++K
Sbjct 635 GSLEDLLQNENLRLDWTFKASLLL---DLIRGLRYLHHRRFPHGRLKSRNCVVDTRFVLK 691
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK-EYKFYYASDVWSFGVTLYELLTH 1097
I D G A+ + E H R + + W APE L+ K + DV+S + L E+LT
Sbjct 692 ITDHGYAEFL-ESHCSSR-PQPAPEELLWTAPELLRGPGKATFKGDVFSLAIILQEVLT- 748
Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157
+ PP L + + ++ L PD+ P E LM+ CWE
Sbjct 749 ----RDPPYCSWGL----SAEEIIRKVASPPPLCRPLVSPDQGPLECIQLMQLCWEEAPD 800
Query 1158 FRPTFENLIPILKTVHEKYQGQAPSV 1183
RP+ + + K+++ QG+ SV
Sbjct 801 DRPSLDQIYTQFKSIN---QGKKTSV 823
>sp|Q6ZLP5|CIPKN_ORYSJ CBL-interacting protein kinase 23 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK23 PE=2 SV=1
Length=450
Score = 80.9 bits (198), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 64/205 (31%), Positives = 100/205 (49%), Gaps = 23/205 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEH 958
R LGEG F KV N +GE VA+K L D +H+ + K+EI ++ + H +
Sbjct 17 RTLGEGTFAKVKF----ARNADSGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 72
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+I+ + + + +VME V G L D + R + + QQ+ + Y H++
Sbjct 73 VIRMHEVMASKTK--IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSR 130
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG------DSPVFWYAPE 1071
HRDL N+LLD +K+ DFGL+ + VREDG +P + APE
Sbjct 131 GVYHRDLKPENLLLDASGTLKVSDFGLSALSQQ------VREDGLLHTTCGTPNY-VAPE 183
Query 1072 CLKEYKFYYA-SDVWSFGVTLYELL 1095
+ + A +D+WS GV L+ L+
Sbjct 184 VINNKGYDGAKADLWSCGVILFVLM 208
Score = 41.2 bits (95), Expect = 0.052, Method: Compositional matrix adjust.
Identities = 61/241 (25%), Positives = 101/241 (42%), Gaps = 30/241 (12%)
Query 639 VVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K+LD H + S M + H ++ +H V + +V E V G L
Sbjct 39 VAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRMHEVMASKTKIYIVMELVTGGEL 98
Query 696 -DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
D R R A K QQL +A+ Y ++ + H ++ N+LL A GT
Sbjct 99 FDKIASRGRLKEDDARKYF--QQLINAVDYCHSRGVYHRDLKPENLLLD----ASGT--- 149
Query 755 IKLSDPGVGLGALSREERVERI--------PWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+K+SD GL ALS++ R + + ++APE + + A D W G L
Sbjct 150 LKVSD--FGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA-DLWSCGVILF- 205
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQ-RPSFRTILRD 865
+ G P + S Y++ + + SCP + +++ L + PS R + +
Sbjct 206 VLMAGYLPFED---SNLMSLYKKIFK-ADFSCPSWFSTSAKKLIKKILDPNPSTRITIAE 261
Query 866 L 866
L
Sbjct 262 L 262
>sp|Q5RD00|AAPK2_PONAB 5'-AMP-activated protein kinase catalytic
subunit alpha-2 OS=Pongo abelii OX=9601 GN=PRKAA2 PE=2 SV=1
Length=552
Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 73/201 (36%), Positives = 95/201 (47%), Gaps = 22/201 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957
LG G FGKV + + TG VAVK L + RS K+EI L+ H
Sbjct 22 LGVGTFGKVKI----GEHQLTGHKVAVKILNRQ---KIRSLDVVGKIKREIQNLKLFRHP 74
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016
HIIK + +VMEYV G L DY+ +H + + QQI + Y H
Sbjct 75 HIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE +
Sbjct 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSNIMSDG-EF--LRTSCGSPNYA-APEVISG- 187
Query 1077 KFYYA--SDVWSFGVTLYELL 1095
+ Y D+WS GV LY LL
Sbjct 188 RLYAGPEVDIWSCGVILYALL 208
Score = 35.8 bits (81), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 24/262 (9%)
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726
H H+ ++ V + MV EYV G L ++ + G V + QQ+ SA+ Y
Sbjct 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKH-GRVEEMEARRLFQQILSAVDYCH 131
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-----WLAP 781
+VH ++ N+LL A K++D GL + + R + AP
Sbjct 132 RHMVVHRDLKPENVLLDAHMNA-------KIAD--FGLSNIMSDGEFLRTSCGSPNYAAP 182
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQ 840
E + G + +D W G L + G P P+ + +PE
Sbjct 183 EVISGRLYA-GPEVDIWSCGVILYALLC-GTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS 240
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+ATL L +P +R + + I R+ + +L L P+ P+ D V +K++
Sbjct 241 VATLLMHMLQVDPLKRATIKDI-REHEWFK-QDLPSYLF--PEDPSYDANVIDDEAVKEV 296
Query 901 RDLGEGHFGKV--SLYCYDPTN 920
+ E +V SLY DP +
Sbjct 297 CEKFECTESEVMNSLYSGDPQD 318
>sp|Q9C6P3|CDPKX_ARATH Calcium-dependent protein kinase 33 OS=Arabidopsis
thaliana OX=3702 GN=CPK33 PE=1 SV=1
Length=521
Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 68/209 (33%), Positives = 103/209 (49%), Gaps = 30/209 (14%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHE- 957
++LG G FG V+ C T TG+ A K++ K + ++EI I++ L +
Sbjct 77 KELGRGQFG-VTYLC---TEKSTGKRFACKSISKKKLVTKGDKEDMRREIQIMQHLSGQP 132
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-------YLPRHSIGLAQLLLFAQQICEG 1010
+I+++KG ED EK++ LVME G L D Y R + + + ++ IC
Sbjct 133 NIVEFKGAYED--EKAVNLVMELCAGGELFDRILAKGHYSERAAASVCRQIVNVVNIC-- 188
Query 1011 MAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
H +HRDL N LL D L+K DFGL+ + EG RV +D ++
Sbjct 189 ----HFMGVMHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEG----RVYKDIVGSAYY 240
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096
APE LK ++ D+WS G+ LY LL+
Sbjct 241 VAPEVLKR-RYGKEIDIWSAGIILYILLS 268
>sp|Q54WJ0|STK11_DICDI Serine/threonine-protein kinase stk11 homolog
OS=Dictyostelium discoideum OX=44689 GN=lkb1 PE=3 SV=1
Length=586
Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 62/201 (31%), Positives = 104/201 (52%), Gaps = 19/201 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK---ADCGPQHRSGWKQEIDILRTLYHEHI 959
LGEG +GKV D + T + VAVK LK P + +EI+I + L+++HI
Sbjct 46 LGEGAYGKVK----DGMDSFTQKRVAVKILKRARLKKIPGGEASVLKEINITKKLHNKHI 101
Query 960 IKYKG--CCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYL 1014
IK E++G+ L +V EYV G+ ++ L P + Q +Q+ E Y+
Sbjct 102 IKLIDHFIIEEKGK--LYIVYEYVGGGTSQNILENAPNGRLPPHQSQFIFRQLIEACEYI 159
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H+Q +HRD+ N+L + ++K+ DFG+A+ + ++ + SP F P L
Sbjct 160 HSQKILHRDIKPDNILFTHANVLKLSDFGVAEDSSQLEDFECLSRSYGSPAF--QPPELT 217
Query 1075 EYKFYYAS---DVWSFGVTLY 1092
+++ ++ D+W+ GVTLY
Sbjct 218 QFQTTFSPFKIDIWAMGVTLY 238
>sp|P42818|KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6
OS=Arabidopsis thaliana OX=3702 GN=ATPK1 PE=1 SV=1
Length=465
Score = 80.9 bits (198), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 63/201 (31%), Positives = 97/201 (48%), Gaps = 15/201 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHE 957
++ +G+G FGKV Y T E+ A+K ++ D H K E DIL + H
Sbjct 137 MKVVGKGAFGKV----YQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHP 192
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL-LFAQQICEGMAYLHA 1016
I++ K Q + L LV++++ G L L + L ++ +I +++LH
Sbjct 193 FIVQLKYSF--QTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHE 250
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075
+ +HRDL N+L+D D V + DFGLAK E R + Y APE ++
Sbjct 251 KGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEEN-----TRSNSMCGTTEYMAPEIVRG 305
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
A+D WS G+ LYE+LT
Sbjct 306 KGHDKAADWWSVGILLYEMLT 326
Score = 35.0 bits (79), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 35/150 (23%), Positives = 62/150 (41%), Gaps = 19/150 (13%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
V ++ SA+S+L K ++H ++ NIL+ T + L+D G+ A EE
Sbjct 236 VYTAEIVSAVSHLHEKGIMHRDLKPENILM-------DTDGHVMLTDFGL---AKEFEEN 285
Query 773 VER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
++APE + G + A D W G L E+ G+ P ++
Sbjct 286 TRSNSMCGTTEYMAPEIVRGKGH--DKAADWWSVGILLYEM-LTGKPPFLGSKGKIQQKI 342
Query 827 YQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
+ + +LP+ + + L EP +R
Sbjct 343 VKDKIKLPQFLSNEAHAILKGLLQKEPERR 372
>sp|Q0D4B2|CIPKL_ORYSJ CBL-interacting protein kinase 21 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK21 PE=2 SV=2
Length=525
Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 67/206 (33%), Positives = 102/206 (50%), Gaps = 23/206 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEH 958
R LGEGHFGKV L + TG A+K L + K+EI L+ L H +
Sbjct 91 RALGEGHFGKVKL----ARHADTGAAFAIKILDRQRILAMKIDEQIKREIATLKLLKHPN 146
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+++ + + + +V+EYV G L D + + + + QQ+ + ++Y H +
Sbjct 147 VVRLHEVSASKTK--IYMVLEYVNGGELFDKIALKGKLSEKEGRKLFQQLMDAVSYCHEK 204
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG------DSPVFWYAPE 1071
HRDL NVL+D +K+ DFGL+ A+P+ R+DG SP + APE
Sbjct 205 GVYHRDLKPENVLVDAKGNIKVSDFGLS-ALPQNQ-----RKDGLLHTTCGSP-NYIAPE 257
Query 1072 CLKEYKFYYA-SDVWSFGVTLYELLT 1096
L + + SD+WS GV LY +LT
Sbjct 258 VLLNRGYDGSLSDIWSCGVILYVMLT 283
Score = 38.9 bits (89), Expect = 0.32, Method: Compositional matrix adjust.
Identities = 55/208 (26%), Positives = 87/208 (42%), Gaps = 35/208 (17%)
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVWLRRERGHVPMAWKMVVAQQLASAL 722
+ H ++ +H V + MV EYV G L + L+ G + + QQL A+
Sbjct 142 LKHPNVVRLHEVSASKTKIYMVLEYVNGGELFDKIALK---GKLSEKEGRKLFQQLMDAV 198
Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI------ 776
SY K + H ++ N+L+ A+G IK+SD GL AL + +R + +
Sbjct 199 SYCHEKGVYHRDLKPENVLVD----AKGN---IKVSD--FGLSALPQNQRKDGLLHTTCG 249
Query 777 --PWLAPECL--PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR--- 829
++APE L G SLS D W G +L + G P ++ YQ+
Sbjct 250 SPNYIAPEVLLNRGYDGSLS---DIWSCG-VILYVMLTGNLPFDDQNTVV---LYQKILK 302
Query 830 -QHRLPEPSCPQLATLTSQCLTYEPTQR 856
R+P+ P + + L P R
Sbjct 303 GDARIPKWLSPGAQDILRKILDPNPITR 330
>sp|Q9ZR08|Y4230_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At4g03230 OS=Arabidopsis thaliana OX=3702
GN=At4g03230 PE=3 SV=3
Length=852
Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 87/281 (31%), Positives = 131/281 (47%), Gaps = 29/281 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V Y G E +AVK L + C Q +K E+ ++ L H ++++
Sbjct 538 LGQGGFGPV----YKGMFPGDQE-IAVKRL-SRCSGQGLEEFKNEVVLIAKLQHRNLVRL 591
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ------ICEGMAYLHA 1016
G C GE+ L L+ EY+P SL ++ L Q L + + I G+ YLH
Sbjct 592 LGYCV-AGEEKL-LLYEYMPHKSLDFFIFDRK--LCQRLDWKMRCNIILGIARGLLYLHQ 647
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRDL N+LLD + KI DFGLA+ + G E + +PE
Sbjct 648 DSRLRIIHRDLKTSNILLDEEMNPKISDFGLAR-IFGGSETSANTNRVVGTYGYMSPEYA 706
Query 1074 KEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
E F + SDV+SFGV + E ++ ++ P K L L+G A R ELL++
Sbjct 707 LEGLFSFKSDVFSFGVVVIETISGKRNTGFHEPEKSLSLLGHAWDLWKAERGIELLDQAL 766
Query 1133 RLPRPDKCPCEVYHLMKN----CWETEASFRPTFENLIPIL 1169
+ + C E + N C + + + RPT N++ +L
Sbjct 767 Q----ESCETEGFLKCLNVGLLCVQEDPNDRPTMSNVVFML 803
Score = 45.8 bits (107), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 42/163 (26%), Positives = 74/163 (45%), Gaps = 20/163 (12%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM-- 712
F L++++ H +L + G CV G E +++ EY+ H LD ++ + + WKM
Sbjct 573 FKNEVVLIAKLQHRNLVRLLGYCVAGEEKLLLYEYMPHKSLDFFIFDRKLCQRLDWKMRC 632
Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGAL 767
+ +A L YL + ++H ++ NIL L E +P K+SD G+ G
Sbjct 633 NIILGIARGLLYLHQDSRLRIIHRDLKTSNIL-----LDEEMNP--KISDFGLARIFGGS 685
Query 768 SREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLE 806
R+ +++PE G S + D + FG ++E
Sbjct 686 ETSANTNRVVGTYGYMSPEYALEGLFSFKS--DVFSFGVVVIE 726
>sp|Q641K5|NUAK1_MOUSE NUAK family SNF1-like kinase 1 OS=Mus musculus
OX=10090 GN=Nuak1 PE=1 SV=1
Length=658
Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 65/229 (28%), Positives = 106/229 (46%), Gaps = 18/229 (8%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDL----GEGHFGKVSLYCYDPTNDGTGEMVAVK 930
A V P P HK LK +L G+G +GKV T +G +VA+K
Sbjct 30 ATAAPVEPRKPHGVKRHHHKHNLKHRYELQETLGKGTYGKVKR----ATERFSGRVVAIK 85
Query 931 ALKADCGPQHRS--GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+++ D ++EI+I+ +L H HII E++ + + ++MEY G L D
Sbjct 86 SIRKDKIKDELDMVHIRREIEIMSSLNHPHIISIYEVFENKDK--IVIIMEYASKGELYD 143
Query 989 YLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
Y+ R + + F +QI + Y H +HRDL N+LLD++ +KI DFGL+
Sbjct 144 YISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNL 203
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELL 1095
++ + + + +PE + + D W+ GV LY L+
Sbjct 204 ----YQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLI 248
Score = 37.0 bits (84), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 14/153 (9%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
+MS ++H H+ ++ V + +++ EY G L ++ ER + +Q+ S
Sbjct 107 IMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYI-SERRRLSERETRHFFRQIVS 165
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---- 776
A+ Y +VH ++ NILL + IK++D GL L ++++ +
Sbjct 166 AVHYCHKNGVVHRDLKLENILL-------DDNCNIKIAD--FGLSNLYQKDKFLQTFCGS 216
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
P A + G +D W G L + +
Sbjct 217 PLYASPEIVNGRPYRGPEVDSWALGVLLYTLIY 249
>sp|P13186|KIN2_YEAST Serine/threonine-protein kinase KIN2 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=KIN2 PE=1 SV=3
Length=1147
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 67/233 (29%), Positives = 101/233 (43%), Gaps = 35/233 (15%)
Query 892 FHKRYLKK---IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQE 947
FH+R L + +G G GKV L + T + + +A KA QH K E
Sbjct 91 FHRRSLGDWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNE 150
Query 948 IDIL-----------------------RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
+IL + LYH HI + C ++ EYV G
Sbjct 151 SEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNH--FYMLFEYVSGG 208
Query 985 SLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
L DY+ +H S+ FA+ I + YLHA + +HRDL N+++ + +KI DFG
Sbjct 209 QLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFG 268
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELL 1095
L+ +Y + +++ APE LK + D+WSFG+ LY L+
Sbjct 269 LSNIF----DYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLV 317
Score = 38.9 bits (89), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 50/211 (24%), Positives = 95/211 (45%), Gaps = 18/211 (9%)
Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQL 718
ASL + H H+ + +C M+ EYV G L ++ + G + A+ +
Sbjct 174 ASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYII-QHGSLKEHHARKFARGI 232
Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER---VER 775
ASAL YL N+VH ++ NI+++ G IK+ D G+ R++
Sbjct 233 ASALQYLHANNIVHRDLKIENIMISSSG-------EIKIIDFGLSNIFDYRKQLHTFCGS 285
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATL-LEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834
+ + APE L + +D W FG L + +C G+ P + S H ++ ++
Sbjct 286 LYFAAPELLKAQPYT-GPEVDIWSFGIVLYVLVC--GKVPFDDEN-SSILHEKIKKGKVD 341
Query 835 EPS--CPQLATLTSQCLTYEPTQRPSFRTIL 863
PS ++ +L ++ + +P +R + + ++
Sbjct 342 YPSHLSIEVISLLTRMIVVDPLRRATLKNVV 372
>sp|Q8BZ25|ANKK1_MOUSE Ankyrin repeat and protein kinase domain-containing
protein 1 OS=Mus musculus OX=10090 GN=Ankk1 PE=2
SV=1
Length=745
Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 66/223 (30%), Positives = 105/223 (47%), Gaps = 24/223 (11%)
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEG 1010
+ + +HI+ G C+ + L +VME++ GSL LP HS+ L +
Sbjct 87 MEKIKFQHIVSIYGVCK----QPLGIVMEFMASGSLEKTLPTHSLCWPLKLRIIHETSLA 142
Query 1011 MAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG-HEYYRVREDGDSPVFW 1067
M +LH+ +H DL N+LLDN+ VKI DFGL+K + + + Y R + +
Sbjct 143 MNFLHSIKPPLLHLDLKPGNILLDNNMHVKISDFGLSKWMEQSTQKQYIERSALRGTLSY 202
Query 1068 YAPECLKEYKFYYAS--DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
PE E DV+SF + ++E+LT Q P L ++ I ++R+
Sbjct 203 IPPEMFLENNKAPGPEYDVYSFAIVIWEILT-----QKKPYAGLNMMTI------IIRVA 251
Query 1126 ELLERGERLPRPDKCPCEVY---HLMKNCWETEASFRPTFENL 1165
+ R D+ P EV+ +LMK CW+ + RP F N+
Sbjct 252 AGM-RPSLQDVSDEWPEEVHQMVNLMKRCWDQDPKKRPCFLNV 293
Score = 35.8 bits (81), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 50/251 (20%), Positives = 96/251 (38%), Gaps = 35/251 (14%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
+E A M ++ H+ ++GVC + P I V E++ G L+ L P+ +++
Sbjct 80 LFEEAVKMEKIKFQHIVSIYGVC-KQPLGI-VMEFMASGSLEKTLPTHSLCWPLKLRIIH 137
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREER 772
LA + L+H ++ NILL + +K+SD G+ + ++++
Sbjct 138 ETSLAMNFLHSIKPPLLHLDLKPGNILL-------DNNMHVKISDFGLSKWMEQSTQKQY 190
Query 773 VER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--------FDGEAPLQSR 818
+ER + ++ PE + D + F + EI + +
Sbjct 191 IERSALRGTLSYIPPEMFLENNKAPGPEYDVYSFAIVIWEILTQKKPYAGLNMMTIIIRV 250
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + PE Q+ L +C +P +RP F + + D+L
Sbjct 251 AAGMRPSLQDVSDEWPE-EVHQMVNLMKRCWDQDPKKRPCFLNVAVE---------TDML 300
Query 879 TVNPDSPASDP 889
SP +DP
Sbjct 301 LSLFQSPMTDP 311
>sp|Q9SR87|LRK61_ARATH Probable L-type lectin-domain containing
receptor kinase VI.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK61
PE=2 SV=1
Length=693
Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 68/210 (32%), Positives = 107/210 (51%), Gaps = 19/210 (9%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+ K+ +G G FG V Y + ++ G +AVK + ++ R + EI+ L L
Sbjct 366 KKFKESEIIGTGGFGIV--YRGNLSSSGP---IAVKKITSNSLQGVRE-FMAEIESLGRL 419
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLF--AQQIC 1008
H++++ +G C+ + E L L+ +Y+P GSL L R+ I L + F + I
Sbjct 420 GHKNLVNLQGWCKHKNE--LLLIYDYIPNGSLDSLLYQTPRRNGIVLPWDVRFEIIKGIA 477
Query 1009 EGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
G+ YLH Q +HRD+ NVL+D D K+GDFGLA+ G + G +
Sbjct 478 SGLLYLHEEWEQIVVHRDVKPSNVLIDEDMNAKLGDFGLARLYERGTLTQTTKIVG--TL 535
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+ APE + K ASDV++FGV L E++
Sbjct 536 GYMAPELTRNGKGSTASDVFAFGVLLLEIV 565
Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 58/238 (24%), Positives = 97/238 (41%), Gaps = 48/238 (20%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL----RRERGHVPMAWKMVVAQQ 717
+ ++ H +L + G C E +++ +Y+ +G LD L RR +P + + +
Sbjct 416 LGRLGHKNLVNLQGWCKHKNELLLIYDYIPNGSLDSLLYQTPRRNGIVLPWDVRFEIIKG 475
Query 718 LASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGALSRE 770
+AS L YL + +VH +V N+L+ A KL D G+ G L++
Sbjct 476 IASGLLYLHEEWEQIVVHRDVKPSNVLIDEDMNA-------KLGDFGLARLYERGTLTQT 528
Query 771 ER-VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
+ V + ++APE G STA D + FG LLEI + P+ E+F+
Sbjct 529 TKIVGTLGYMAPELTRNGKG--STASDVFAFGVLLLEI-------VCGNKPTNAENFFLA 579
Query 830 QHRLPEPSCPQLATLTSQ--------------------CLTYEPTQRPSFRTILRDLT 867
+ + + + Q C +P RPS R +LR L
Sbjct 580 DWVMEFHTNGGILCVVDQNLGSSFNGREAKLALVVGLLCCHQKPKFRPSMRMVLRYLN 637
>sp|Q13233|M3K1_HUMAN Mitogen-activated protein kinase kinase
kinase 1 OS=Homo sapiens OX=9606 GN=MAP3K1 PE=1 SV=4
Length=1512
Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 64/243 (26%), Positives = 119/243 (49%), Gaps = 23/243 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDP--TVFHKRYLK-----KIRDLGEGHFGKVSLYCYDPTN 920
+LQ N D++ + D+P + P T + Y + K + +G G F CY +
Sbjct 1207 QLQVENGEDIIIIQQDTPETLPGHTKAKQPYREDTEWLKGQQIGLGAFSS----CYQAQD 1262
Query 921 DGTGEMVAVKAL---KADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGC-CEDQGEKSL 974
GTG ++AVK + + Q ++EI ++ L H +II+ G CE + +
Sbjct 1263 VGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCE---KSNY 1319
Query 975 QLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033
L +E++ GS+ L ++ +++ + +Q+ G++YLH IHRD+ N+L+D+
Sbjct 1320 NLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDS 1379
Query 1034 D-RLVKIGDFG-LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091
+ ++I DFG A+ +G + + + APE L+ ++ + DVWS G +
Sbjct 1380 TGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAI 1439
Query 1092 YEL 1094
E+
Sbjct 1440 IEM 1442
Score = 49.3 bits (116), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 52/227 (23%), Positives = 95/227 (42%), Gaps = 16/227 (7%)
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHG-VCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
++ A E +MS ++H ++ + G C + N+ + E++ G + L + G
Sbjct 1284 QEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFI-EWMAGGSV-AHLLSKYGAF 1341
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF---IKLSDPGVG 763
+ + +QL LSYL ++H +V G N+L+ G + F +L+ G G
Sbjct 1342 KESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTG 1401
Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE- 822
G + + + I ++APE L G + D W G ++E+ + P + S
Sbjct 1402 AGEF-QGQLLGTIAFMAPEVLRG--QQYGRSCDVWSVGCAIIEMAC-AKPPWNAEKHSNH 1457
Query 823 -----KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
K +P P L + +CL +P RP R +L+
Sbjct 1458 LALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLK 1504
>sp|A3B529|CIPKS_ORYSJ CBL-interacting protein kinase 28 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK28 PE=2 SV=2
Length=435
Score = 80.5 bits (197), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 71/221 (32%), Positives = 108/221 (49%), Gaps = 31/221 (14%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD----CGPQHRSGWK 945
+V +RY+ R LG+G FGKV Y N +G+ VA+K + + G + K
Sbjct 5 SVLMERYVIG-RQLGQGTFGKV----YYARNLSSGQSVAIKMIDKEKILKVGLMEQ--IK 57
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA 1004
+EI I+R + H ++++ E KS + +EY G L + R + +
Sbjct 58 REISIMRLVRHPNVLQ---LFEVMATKSNIYFALEYAKGGELFHKMARAKLNEESARNYF 114
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG--- 1061
QQ+ M Y H++ HRDL N+LLD + +K+ DFGL+ A+ E R+DG
Sbjct 115 QQLISAMDYCHSRGVYHRDLKPENLLLDENETLKVSDFGLS-ALAESR-----RQDGLLH 168
Query 1062 ---DSPVFWYAPECLKEYKFYYAS--DVWSFGVTLYELLTH 1097
+P + APE L K Y S DVWS GV L+ L+ +
Sbjct 169 TACGTPAY-VAPEVLSR-KGYSGSKADVWSCGVILFVLVAN 207
Score = 41.6 bits (96), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 72/313 (23%), Positives = 119/313 (38%), Gaps = 49/313 (16%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LGQGT VY R SG KM D++ ++ + +++ +I
Sbjct 16 QLGQGTFGKVYYAR--NLSSGQSVAIKMIDKEKILK-----------VGLMEQIKREI-- 60
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
S+M V H ++ + V EY + G L + R + + A
Sbjct 61 ------SIMRLVRHPNVLQLFEVMATKSNIYFALEYAKGGELFHKMARAKLNEESARNYF 114
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
QQL SA+ Y ++ + H ++ N+LL + +K+SD GL AL+ R
Sbjct 115 --QQLISAMDYCHSRGVYHRDLKPENLLL-------DENETLKVSD--FGLSALAESRRQ 163
Query 774 ERI--------PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-E 824
+ + ++APE L S S A D W G L + P R+ +
Sbjct 164 DGLLHTACGTPAYVAPEVLSRKGYSGSKA-DVWSCGVILF-VLVANYLPFHDRNIIQMYR 221
Query 825 HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP------HNLADVL 878
+ ++R P +L L L +P+ R S I R +P +N
Sbjct 222 KIAKAEYRCPRHFSAELKELLYGILDPDPSTRMSISRIKRSAWYRKPIAISALNNETGKK 281
Query 879 TVNPDSPASDPTV 891
+ ++P S PT+
Sbjct 282 SCTSEAPFSGPTI 294
>sp|Q69Q47|CIPKO_ORYSJ CBL-interacting protein kinase 24 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK24 PE=1 SV=1
Length=453
Score = 80.9 bits (198), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/199 (30%), Positives = 98/199 (49%), Gaps = 13/199 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTLYHEH 958
R +G+G F KV + TG VA+K L D HR K+EI I++ + H +
Sbjct 22 RTIGQGTFAKVKF----AVDADTGAAVAMKVLDKDTILNHRMLHQIKREISIMKIVRHPN 77
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQ 1017
I++ G+ + +++E + G L D + R + + + QQ+ + + Y H++
Sbjct 78 IVRLNEVL--AGKTKIYIILELITGGELFDKIARQGKLRENEARKYFQQLIDAINYCHSK 135
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
HRDL N+LLD+ +K+ DFGL+ +G + +P + APE L
Sbjct 136 GVYHRDLKPENLLLDSRGNLKVSDFGLSTLAQKGVGL--LHTTCGTP-NYVAPEVLSNNG 192
Query 1078 FY-YASDVWSFGVTLYELL 1095
+ A+DVWS GV LY L+
Sbjct 193 YDGSAADVWSCGVILYVLM 211
Score = 38.9 bits (89), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 55/232 (24%), Positives = 89/232 (38%), Gaps = 12/232 (5%)
Query 639 VVLKVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +KVLD +H + S+M V H ++ ++ V + ++ E + G L
Sbjct 44 VAMKVLDKDTILNHRMLHQIKREISIMKIVRHPNIVRLNEVLAGKTKIYIILELITGGEL 103
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPF 754
+ R+ G + QQL A++Y +K + H ++ N+LL +R L
Sbjct 104 FDKIARQ-GKLRENEARKYFQQLIDAINYCHSKGVYHRDLKPENLLLDSRGNLKVSDFGL 162
Query 755 IKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
L+ GVGL ++APE L S A D W G +L + G P
Sbjct 163 STLAQKGVGL----LHTTCGTPNYVAPEVLSNNGYDGSAA-DVWSCG-VILYVLMAGYLP 216
Query 815 LQSRS-PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ P+ + Q P P +L + L P R + I D
Sbjct 217 FEEDDLPTLYDKITAGQFSCPYWFSPGATSLIHRILDPNPKTRITIEQIRED 268
>sp|Q9SYS3|CRK40_ARATH Cysteine-rich receptor-like protein kinase
40 OS=Arabidopsis thaliana OX=3702 GN=CRK40 PE=2 SV=1
Length=654
Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 64/201 (32%), Positives = 97/201 (48%), Gaps = 16/201 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V + G+ VAVK L G Q +K E+ +L L H++++K
Sbjct 354 LGQGGFGTVYKGTFP-----NGQEVAVKRLTKGSG-QGDMEFKNEVSLLTRLQHKNLVKL 407
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017
G C ++G++ + LV E+VP SL ++ R + + I G+ YLH
Sbjct 408 LGFC-NEGDEEI-LVYEFVPNSSLDHFIFDEDKRSLLTWEVRFRIIEGIARGLLYLHEDS 465
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
IHRDL A N+LLD + K+ DFG A+ + + + APE L
Sbjct 466 QLKIIHRDLKASNILLDAEMNPKVADFGTARLFDSDETRAETKRIAGTRGY-MAPEYLNH 524
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
+ SDV+SFGV L E+++
Sbjct 525 GQISAKSDVYSFGVMLLEMIS 545
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 56/186 (30%), Positives = 87/186 (47%), Gaps = 22/186 (12%)
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
GQE V +K L + F SL++++ H +L + G C G E I+V E+V +
Sbjct 369 NGQE--VAVKRLTKGSGQGDMEFKNEVSLLTRLQHKNLVKLLGFCNEGDEEILVYEFVPN 426
Query 693 GPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGL 747
LD ++ E + W + + + +A L YL + ++H ++ NILL
Sbjct 427 SSLDHFIFDEDKRSLLTWEVRFRIIEGIARGLLYLHEDSQLKIIHRDLKASNILLD---- 482
Query 748 AEGTSPFIKLSDPGVGLGALSREERVE--RIP----WLAPECLPGGANSLSTAMDKWGFG 801
AE +P K++D G S E R E RI ++APE L G +S D + FG
Sbjct 483 AE-MNP--KVADFGTARLFDSDETRAETKRIAGTRGYMAPEYLNHG--QISAKSDVYSFG 537
Query 802 ATLLEI 807
LLE+
Sbjct 538 VMLLEM 543
>sp|Q39192|SRK2D_ARATH Serine/threonine-protein kinase SRK2D OS=Arabidopsis
thaliana OX=3702 GN=SRK2D PE=1 SV=1
Length=362
Score = 79.7 bits (195), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 77/229 (34%), Positives = 111/229 (48%), Gaps = 24/229 (10%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935
D T +P P P + ++D+G G+FG L T+ T E+VAVK ++
Sbjct 2 DPATNSPIMPIDLPIMHDSDRYDFVKDIGSGNFGVARLM----TDRVTKELVAVKYIER- 56
Query 936 CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PR 992
G + ++EI R+L H +I+++K L +VMEY G L + + R
Sbjct 57 -GEKIDENVQREIINHRSLRHPNIVRFKEVI--LTPSHLAIVMEYAAGGELYERICNAGR 113
Query 993 HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVP 1049
S A+ F QQ+ G++Y HA HRDL N LLD RL KI DFG +K+
Sbjct 114 FSEDEARF--FFQQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRL-KICDFGYSKS-- 168
Query 1050 EGHEYYRVREDGDSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELLT 1096
+ + + +P + APE L +EY A DVWS GVTLY +L
Sbjct 169 -SVLHSQPKSTVGTPA-YIAPEILLRQEYDGKLA-DVWSCGVTLYVMLV 214
>sp|P25323|MYLKA_DICDI Myosin light chain kinase A OS=Dictyostelium
discoideum OX=44689 GN=mlkA PE=1 SV=2
Length=295
Score = 79.0 bits (193), Expect = 2e-14, Method: Composition-based stats.
Identities = 67/199 (34%), Positives = 94/199 (47%), Gaps = 15/199 (8%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHII 960
+LG G F V Y N T + A+K + K++ G + K E+DIL+ + H +II
Sbjct 13 ELGRGAFSIV----YLGENKQTKQRYAIKVINKSELGKDYEKNLKMEVDILKKVNHPNII 68
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
K D EK L LVME V G L D + + S A ++I + YLH +
Sbjct 69 ALKELF-DTPEK-LYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGLNI 126
Query 1020 IHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL N+LL +N V I DFGL+K + + V + + APE L
Sbjct 127 VHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQT----LVMQTACGTPSYVAPEVLNAT 182
Query 1077 KFYYASDVWSFGVTLYELL 1095
+ D+WS GV Y LL
Sbjct 183 GYDKEVDMWSIGVITYILL 201
>sp|Q6UD73|LYK3_MEDTR LysM domain receptor-like kinase 3 OS=Medicago
truncatula OX=3880 GN=LYK3 PE=1 SV=1
Length=620
Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 81/286 (28%), Positives = 126/286 (44%), Gaps = 34/286 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FG V + GE A+K + Q S + E+ +L ++H ++++
Sbjct 328 IGQGGFGAVYY------AELRGEKTAIKKMDV----QASSEFLCELKVLTHVHHLNLVRL 377
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017
G C E SL LV E++ G+L YL H IG L + A G+ Y+H
Sbjct 378 IGYCV---EGSLFLVYEHIDNGNLGQYL--HGIGTEPLPWSSRVQIALDSARGLEYIHEH 432
Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
YIHRD+ + N+L+D + K+ DFGL K + G+ R G F Y P
Sbjct 433 TVPVYIHRDVKSANILIDKNLRGKVADFGLTKLIEVGNSTLHTRLVG---TFGYMPPEYA 489
Query 1075 EY-KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+Y DV++FGV LYEL+T ++ E G+ Q L + LE +
Sbjct 490 QYGDVSPKIDVYAFGVVLYELITAKNAVLKTGESVAESKGLVQLFEEALHRMDPLEGLRK 549
Query 1134 L--PR-----PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
L PR P ++ L + C RP+ +++ L T+
Sbjct 550 LVDPRLKENYPIDSVLKMAQLGRACTRDNPLLRPSMRSIVVALMTL 595
>sp|Q9S9M2|WAKLD_ARATH Wall-associated receptor kinase-like 4
OS=Arabidopsis thaliana OX=3702 GN=WAKL4 PE=2 SV=2
Length=761
Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 76/252 (30%), Positives = 114/252 (45%), Gaps = 23/252 (9%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
G +VAVK KA + E+ +L + H +I+K GCC + + LV E+VP
Sbjct 446 GRIVAVKRSKA-MDEDKVEEFINEVVVLAQINHRNIVKLLGCCLET--EVPVLVYEFVPN 502
Query 984 GSL----RDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI---HRDLAARNVLLDNDRL 1036
G L RD + + L A +I ++YLH+ HRD+ N+LLD
Sbjct 503 GDLCKRLRDECDDYIMTWEVRLHIAIEIAGALSYLHSAASFPIYHRDIKTTNILLDEKYQ 562
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA-PECLKEYKFYYASDVWSFGVTLYELL 1095
VK+ DFG +++V + + G F Y PE + KF SDV+SFGV L EL+
Sbjct 563 VKVSDFGTSRSVTIDQTHLTTQVAG---TFGYVDPEYFQSSKFTDKSDVYSFGVVLVELI 619
Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE-RGERLPRPDKCPCE----VYHLMKN 1150
T + S ++ E G A + ++ L+ ER+ D+C + V L K
Sbjct 620 TGKNPSSRVQSE--ENRGFAAHFVAAVKENRFLDIVDERI--KDECNLDQVMAVAKLAKR 675
Query 1151 CWETEASFRPTF 1162
C + RP
Sbjct 676 CLNRKGKKRPNM 687
Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 72/305 (24%), Positives = 124/305 (41%), Gaps = 65/305 (21%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LGQG + VY+G L V GR V +K D
Sbjct 430 LGQGGQGTVYKGML-------------------VDGR------IVAVKRSKAMDEDKVEE 464
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F +++Q++H ++ + G C+ ++V E+V +G L LR E M W ++
Sbjct 465 FINEVVVLAQINHRNIVKLLGCCLETEVPVLVYEFVPNGDLCKRLRDECDDYIMTWEVRL 524
Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+A ++A ALSYL + + H ++ NILL +K+SD G
Sbjct 525 HIAIEIAGALSYLHSAASFPIYHRDIKTTNILLDE-------KYQVKVSDFGTSRSVTID 577
Query 770 EERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ + ++ PE ++ + D + FG L+E+ G+ P SR SE+
Sbjct 578 QTHLTTQVAGTFGYVDPEYFQ--SSKFTDKSDVYSFGVVLVEL-ITGKNP-SSRVQSEEN 633
Query 825 -----HFYQ--RQHRL---------PEPSCPQ---LATLTSQCLTYEPTQRPSFRTILRD 865
HF +++R E + Q +A L +CL + +RP+ R + +
Sbjct 634 RGFAAHFVAAVKENRFLDIVDERIKDECNLDQVMAVAKLAKRCLNRKGKKRPNMREVSVE 693
Query 866 LTRLQ 870
L R++
Sbjct 694 LERIR 698
>sp|Q54RB2|CDK11_DICDI Cyclin-dependent kinase 11 OS=Dictyostelium
discoideum OX=44689 GN=cdk11 PE=3 SV=1
Length=358
Score = 79.7 bits (195), Expect = 2e-14, Method: Composition-based stats.
Identities = 62/207 (30%), Positives = 106/207 (51%), Gaps = 18/207 (9%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILR 952
KK+ + EG FG V YC + T E+VA+K +K + + R G +EI +L
Sbjct 52 FKKLYTINEGAFGVV--YC--AQDKETEEIVALKKIKME---REREGIPITSVREIKVLM 104
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQICEG 1010
L H++I++ K + S+ + ME++ L L + + + + +++ QQ+ G
Sbjct 105 ELKHDNIVQIKEIVLGKNINSIFMAMEFIDHDLRGLMEVIKKPFLP-SEIKTLIQQLLNG 163
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
++Y+H IHRDL N+L N ++KI DFGLA+ E + G +++ AP
Sbjct 164 VSYMHDNWVIHRDLKTANLLYTNKGVLKIADFGLAR---EYGSPLKPLSKGVVTLWYRAP 220
Query 1071 ECLKEYKFYY-ASDVWSFGVTLYELLT 1096
E L + + Y A D+WS G E+++
Sbjct 221 ELLLDTEIYTPAIDIWSVGCIFAEIIS 247
>sp|P0DL10|TD1_MAIZE Leucine-rich repeat receptor-like kinase
protein THICK TASSEL DWARF1 OS=Zea mays OX=4577 GN=TD1 PE=2
SV=1
Length=996
Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 81/288 (28%), Positives = 122/288 (42%), Gaps = 24/288 (8%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
LK+ +G+G G V Y G E+ + + CG H G+ E+ L + H
Sbjct 703 LKEDNIIGKGGAGIV----YHGVTRGGAELAIKRLVGRGCG-DHDRGFTAEVTTLGRIRH 757
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMAY 1013
+I++ G ++ E +L L+ EY+P GSL + L G A + G+ Y
Sbjct 758 RNIVRLLGFVSNR-EANL-LLYEYMPNGSLGEMLHGGKGGHLGWEARARVAAEAARGLCY 815
Query 1014 LH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
LH A IHRD+ + N+LLD+ + DFGLAK + G + AP
Sbjct 816 LHHDCAPRIIHRDVKSNNILLDSAFEAHVADFGLAKFLGGGGATSECMSAIAGSYGYIAP 875
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ------GQMTVLRL 1124
E + SDV+SFGV L EL+T + P F + + I
Sbjct 876 EYAYTLRVDEKSDVYSFGVVLLELIT----GRRPVGSFGDGVDIVHWVRKVTADAAAAEE 931
Query 1125 TELLERGERL-PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
LL RL P P ++Y + C E ++ RPT ++ +L T
Sbjct 932 PVLLVADRRLAPEPVPLLADLYRVAMACVEEASTARPTMREVVHMLST 979
>sp|Q9LZU4|CRK4_ARATH Cysteine-rich receptor-like protein kinase
4 OS=Arabidopsis thaliana OX=3702 GN=CRK4 PE=2 SV=1
Length=676
Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 83/287 (29%), Positives = 127/287 (44%), Gaps = 35/287 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+V + +G VAVK L G R + E+ ++ L H ++++
Sbjct 357 LGQGGFGEVYKGIFP-----SGVQVAVKRLSKTSGQGERE-FANEVIVVAKLQHRNLVRL 410
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ------ICEGMAYLHA 1016
G C ++ E+ L V E+VP SL DY S + LL + ++ I G+ YLH
Sbjct 411 LGFCLERDERIL--VYEFVPNKSL-DYFIFDST-MQSLLDWTRRYKIIGGIARGILYLHQ 466
Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRDL A N+LL +D KI DFG+A+ R + + +PE
Sbjct 467 DSRLTIIHRDLKAGNILLGDDMNAKIADFGMARIFGMDQTEANTRRIVGT-YGYMSPEYA 525
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+F SDV+SFGV + E++ S + ++ G + G + V L G
Sbjct 526 MYGQFSMKSDVYSFGVLVLEII-----SGKKNSNVYQMDGTSAGNL-VTYTWRLWSNGSP 579
Query 1134 LPRPDKCPCEVY---------HLMKNCWETEASFRPTFENLIPILKT 1171
L D + Y H+ C + EA RPT ++ +L T
Sbjct 580 LELVDPSFRDNYRINEVSRCIHIALLCVQEEAEDRPTMSAIVQMLTT 626
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 61/269 (23%), Positives = 110/269 (41%), Gaps = 55/269 (20%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
++V +K L + F +++++ H +L + G C+ E I+V E+V + LD
Sbjct 374 VQVAVKRLSKTSGQGEREFANEVIVVAKLQHRNLVRLLGFCLERDERILVYEFVPNKSLD 433
Query 697 VWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGT 751
++ + W + + +A + YL + ++H ++ NILL G
Sbjct 434 YFIFDSTMQSLLDWTRRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNILL-------GD 486
Query 752 SPFIKLSDPGVG--LGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLL 805
K++D G+ G E RI +++PE G S+ + D + FG +L
Sbjct 487 DMNAKIADFGMARIFGMDQTEANTRRIVGTYGYMSPEYAMYGQFSMKS--DVYSFGVLVL 544
Query 806 EIC----------FDGE----------------APLQSRSPSEKEHFYQRQHRLPEPS-C 838
EI DG +PL+ PS ++++ R+ E S C
Sbjct 545 EIISGKKNSNVYQMDGTSAGNLVTYTWRLWSNGSPLELVDPSFRDNY-----RINEVSRC 599
Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+A L C+ E RP+ I++ LT
Sbjct 600 IHIALL---CVQEEAEDRPTMSAIVQMLT 625
>sp|Q9ZVR7|PSKR1_ARATH Phytosulfokine receptor 1 OS=Arabidopsis
thaliana OX=3702 GN=PSKR1 PE=1 SV=4
Length=1008
Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 61/183 (33%), Positives = 92/183 (50%), Gaps = 17/183 (9%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
G+ VA+K L DCG R ++ E++ L H +++ +G C + ++ L+ Y+
Sbjct 756 GKKVAIKKLSGDCGQIERE-FEAEVETLSRAQHPNLVLLRGFCFYKNDR--LLIYSYMEN 812
Query 984 GSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDR 1035
GSL +L + G A L L AQ +G+ YLH H +HRD+ + N+LLD +
Sbjct 813 GSLDYWLHERNDGPALLKWKTRLRIAQGAAKGLLYLHEGCDPHILHRDIKSSNILLDENF 872
Query 1036 LVKIGDFGLAKAVP--EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
+ DFGLA+ + E H V D + + PE + Y DV+SFGV L E
Sbjct 873 NSHLADFGLARLMSPYETH----VSTDLVGTLGYIPPEYGQASVATYKGDVYSFGVVLLE 928
Query 1094 LLT 1096
LLT
Sbjct 929 LLT 931
Score = 57.4 bits (137), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 52/188 (28%), Positives = 82/188 (44%), Gaps = 28/188 (15%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K L I F +S+ H +L + G C + +++ Y+E+G LD
Sbjct 758 KVAIKKLSGDCGQIEREFEAEVETLSRAQHPNLVLLRGFCFYKNDRLLIYSYMENGSLDY 817
Query 698 WL-RRERGHVPMAWK--MVVAQQLASALSYLE---NKNLVHGNVCGRNIL--------LA 743
WL R G + WK + +AQ A L YL + +++H ++ NIL LA
Sbjct 818 WLHERNDGPALLKWKTRLRIAQGAAKGLLYLHEGCDPHILHRDIKSSNILLDENFNSHLA 877
Query 744 RLGLAEGTSPF-IKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
GLA SP+ +S VG + ++ PE G A+ + D + FG
Sbjct 878 DFGLARLMSPYETHVSTDLVG-----------TLGYIPPEY--GQASVATYKGDVYSFGV 924
Query 803 TLLEICFD 810
LLE+ D
Sbjct 925 VLLELLTD 932
>sp|P07527|WEE1_SCHPO Mitosis inhibitor protein kinase wee1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=wee1 PE=1 SV=1
Length=877
Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 64/206 (31%), Positives = 101/206 (49%), Gaps = 22/206 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLY 955
+ + LG G F +V DP AVK LK GP+ R+ QE+ I R L
Sbjct 566 FRNVTLLGSGEFSEV-FQVEDPVEKTLK--YAVKKLKVKFSGPKERNRLLQEVSIQRALK 622
Query 956 -HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ-----QICE 1009
H+HI++ E G L + +E GSL +L L++L F ++
Sbjct 623 GHDHIVELMDSWEHGG--FLYMQVELCENGSLDRFLEEQG-QLSRLDEFRVWKILVEVAL 679
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFW 1067
G+ ++H ++Y+H DL NV++ + +KIGDFG+A VP G E +GD +
Sbjct 680 GLQFIHHKNYVHLDLKPANVMITFEGTLKIGDFGMASVWPVPRGME-----REGD--CEY 732
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYE 1093
APE L + + +D++S G+T++E
Sbjct 733 IAPEVLANHLYDKPADIFSLGITVFE 758
Score = 34.7 bits (78), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 39/135 (29%), Positives = 63/135 (47%), Gaps = 27/135 (20%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPM-----AWKMVVAQQLASALSYLENKNLVHGNVCGRN 739
M E E+G LD +L E+G + WK++V ++A L ++ +KN VH ++ N
Sbjct 642 MQVELCENGSLDRFLE-EQGQLSRLDEFRVWKILV--EVALGLQFIHHKNYVHLDLKPAN 698
Query 740 ILLARLGLAEGTSPFIKLSDPGVGL-----GALSREERVERIPWLAPECLPGGANSL-ST 793
+++ EGT +K+ D G+ + RE E ++APE L AN L
Sbjct 699 VMIT----FEGT---LKIGDFGMASVWPVPRGMEREGDCE---YIAPEVL---ANHLYDK 745
Query 794 AMDKWGFGATLLEIC 808
D + G T+ E
Sbjct 746 PADIFSLGITVFEAA 760
>sp|P13863|CDK1_CHICK Cyclin-dependent kinase 1 OS=Gallus gallus
OX=9031 GN=CDK1 PE=1 SV=1
Length=303
Score = 79.0 bits (193), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 63/216 (29%), Positives = 108/216 (50%), Gaps = 27/216 (13%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957
KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L+H
Sbjct 6 KIEKIGEGTYGVV----YKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELHHP 61
Query 958 HIIKYKGCCED--QGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGM 1011
+I+ C +D + L L+ E++ + L+ YL + +++ + QI +G+
Sbjct 62 NIV----CLQDVLMQDARLYLIFEFLSM-DLKKYLDTIPSGQYLDRSRVKSYLYQILQGI 116
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-AP 1070
+ H++ +HRDL +N+L+D+ ++K+ DFGLA+A Y + WY +P
Sbjct 117 VFCHSRRVLHRDLKPQNLLIDDKGVIKLADFGLARAFGIPVRVYT----HEVVTLWYRSP 172
Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLT-----HCDS 1100
E L Y D+WS G EL T H DS
Sbjct 173 EVLLGSALYSTPVDIWSIGTIFAELATKKPLFHGDS 208
>sp|Q9H1R3|MYLK2_HUMAN Myosin light chain kinase 2, skeletal/cardiac
muscle OS=Homo sapiens OX=9606 GN=MYLK2 PE=1 SV=3
Length=596
Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/198 (30%), Positives = 99/198 (50%), Gaps = 15/198 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V C + TG +A K +K P+ + EI+++ L H ++I+
Sbjct 291 LGGGKFGAV-CTCME---KATGLKLAAKVIKKQT-PKDKEMVLLEIEVMNQLNHRNLIQL 345
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020
E E + L MEY+ G L + + L ++ ++F +QIC+G+ ++H +
Sbjct 346 YAAIETPHE--IVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVL 403
Query 1021 HRDLAARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
H DL N+L N LVKI DFGLA+ + +++ + +P F +PE + +
Sbjct 404 HLDLKPENILCVNTTGHLVKIIDFGLARRY---NPNEKLKVNFGTPEF-LSPEVVNYDQI 459
Query 1079 YYASDVWSFGVTLYELLT 1096
+D+WS GV Y LL+
Sbjct 460 SDKTDMWSMGVITYMLLS 477
Score = 36.2 bits (82), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 37/169 (22%), Positives = 70/169 (41%), Gaps = 21/169 (12%)
Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
V+K P ++ L E +M+Q++H +L ++ E ++ EY+E G L +
Sbjct 315 VIKKQTPKDKEMVLLEIE---VMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERI 371
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
E H+ MV +Q+ + ++ ++H ++ NIL T +K+ D
Sbjct 372 VDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNT-----TGHLVKIID 426
Query 760 PGVGLGALSREERVERIP-------WLAPECLPGGANSLSTAMDKWGFG 801
G R E++ +L+PE + + +S D W G
Sbjct 427 ----FGLARRYNPNEKLKVNFGTPEFLSPEVV--NYDQISDKTDMWSMG 469
>sp|Q924I2|M4K3_RAT Mitogen-activated protein kinase kinase kinase
kinase 3 OS=Rattus norvegicus OX=10116 GN=Map4k3 PE=1 SV=2
Length=873
Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 56/199 (28%), Positives = 102/199 (51%), Gaps = 14/199 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I+ +G G +G V Y N TGE+ A+K +K + G + + +QEI +++ H +I
Sbjct 19 IQRIGSGTYGDV----YKARNVNTGELAAIKVIKLEPG-EDFAVVQQEIIMMKDCKHANI 73
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ Y G + + L + ME+ GSL+D Y + Q+ +++ +G+ YLH++
Sbjct 74 VAYFGSYLRRDK--LWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKG 131
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL---KE 1075
+HRD+ N+LL ++ VK+ DFG++ + R+ +W APE ++
Sbjct 132 KMHRDIKGANILLTDNGHVKLADFGVSAQITAT---IAKRKSFIGTPYWMAPEVAAVERK 188
Query 1076 YKFYYASDVWSFGVTLYEL 1094
+ D+W+ G+T EL
Sbjct 189 GGYNQLCDLWAVGITAIEL 207
Score = 41.2 bits (95), Expect = 0.072, Method: Compositional matrix adjust.
Identities = 73/322 (23%), Positives = 122/322 (38%), Gaps = 59/322 (18%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
R Q++ + +G GT +VY+ R + G+ + +
Sbjct 10 RNPQEDFELIQRIGSGTYGDVYKAR----------------------NVNTGELAAIKVI 47
Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRR 701
L+P D A+ E +M H ++ G +R + + E+ G L D++
Sbjct 48 KLEPGE-DFAVVQQEII-MMKDCKHANIVAYFGSYLRRDKLWICMEFCGGGSLQDIY--H 103
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
G + V+++ L YL +K +H ++ G NILL G +KL+D G
Sbjct 104 VTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNG-------HVKLADFG 156
Query 762 VG---LGALSREERVERIP-WLAPECLP----GGANSLSTAMDKWGFGATLLEIC----- 808
V +++ + P W+APE GG N L D W G T +E+
Sbjct 157 VSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLC---DLWAVGITAIELAELQPP 213
Query 809 -FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD-- 865
FD P+++ K +F + + LT P +RP+ +L+
Sbjct 214 MFDLH-PMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPF 272
Query 866 ----LTRLQPHNLADVLTVNPD 883
LTR L D + NPD
Sbjct 273 VTQPLTRSLAIELLDKVN-NPD 293
>sp|Q91604|STK11_XENLA Serine/threonine-protein kinase stk11 OS=Xenopus
laevis OX=8355 GN=stk11 PE=1 SV=1
Length=432
Score = 80.5 bits (197), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/198 (30%), Positives = 95/198 (48%), Gaps = 6/198 (3%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG +GKV D + +K K P + K+EI +LR L H ++I+
Sbjct 58 LGEGSYGKVK-EMLDSDTLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHRNVIQL 116
Query 963 KGCCEDQGEKSLQLVMEYVPLG--SLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
++ ++ + +VMEY G + D + + Q + Q+ +G+ YLH+Q +
Sbjct 117 VDVLYNEEKQKMYMVMEYCVCGMQEMLDSVQDKHFPVFQAHGYFCQLIDGLEYLHSQGIV 176
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
H+D+ N+LL D +KI D G+A+A+ E R SP F PE +
Sbjct 177 HKDIKPGNLLLTTDGTLKISDLGVAEALHPFAEGDTCRTSQGSPAFQ-PPEIANGLDTFS 235
Query 1080 -YASDVWSFGVTLYELLT 1096
+ D+WS GVTLY + T
Sbjct 236 GFKVDIWSAGVTLYNITT 253
Score = 48.1 bits (113), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 53/213 (25%), Positives = 86/213 (40%), Gaps = 21/213 (10%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL-- 742
MV EY G ++ + H P+ QL L YL ++ +VH ++ N+LL
Sbjct 130 MVMEYCVCGMQEMLDSVQDKHFPVFQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTT 189
Query 743 ------ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLST-AM 795
+ LG+AE PF + G+ P P + G ++ S +
Sbjct 190 DGTLKISDLGVAEALHPFAEGDTCRTSQGS----------PAFQPPEIANGLDTFSGFKV 239
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854
D W G TL I G P + + + E+ + + +PE P L+ L L Y+P
Sbjct 240 DIWSAGVTLYNIT-TGLYPFEGDNIYKLFENIGKGDYSIPEECGPLLSDLLRGMLEYDPA 298
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
+R S + I + + H D + P SP +
Sbjct 299 KRFSIQQIRQHNWFRKKHPHMDPIVPIPPSPET 331
>sp|Q9LFV3|CRLK2_ARATH Calcium/calmodulin-regulated receptor-like
kinase 2 OS=Arabidopsis thaliana OX=3702 GN=CRLK2 PE=2 SV=1
Length=436
Score = 80.5 bits (197), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 62/220 (28%), Positives = 99/220 (45%), Gaps = 23/220 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V GE+ A K ++ R ++ E+ +L L+H +++
Sbjct 120 LGQGSFGPVYKAVMP-----NGELAAAKVHGSNSSQGDRE-FQTEVSLLGRLHHRNLVNL 173
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
G C D+ + L+ E++ GSL + L + + L A I G+ YLH
Sbjct 174 TGYCVDKSHR--MLIYEFMSNGSLENLLYGGEGMQVLNWEERLQIALDISHGIEYLHEGA 231
Query 1019 Y---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
IHRDL + N+LLD+ K+ DFGL+K + R+ + P +
Sbjct 232 VPPVIHRDLKSANILLDHSMRAKVADFGLSKEMV----LDRMTSGLKGTHGYMDPTYIST 287
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
K+ SD++SFGV + EL+T P +E I +A
Sbjct 288 NKYTMKSDIYSFGVIILELITAI----HPQQNLMEYINLA 323
Score = 42.4 bits (98), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 50/240 (21%), Positives = 100/240 (42%), Gaps = 39/240 (16%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F SL+ ++ H +L + G CV +++ E++ +G L+ L G + W ++
Sbjct 155 FQTEVSLLGRLHHRNLVNLTGYCVDKSHRMLIYEFMSNGSLENLLYGGEGMQVLNWEERL 214
Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+A ++ + YL ++H ++ NILL S K++D G LS+
Sbjct 215 QIALDISHGIEYLHEGAVPPVIHRDLKSANILLDH-------SMRAKVADFG-----LSK 262
Query 770 EERVERIP--------WLAPECLPGGANSLSTAMDKWGFGATLLEIC--------FDGEA 813
E ++R+ ++ P + N + D + FG +LE+
Sbjct 263 EMVLDRMTSGLKGTHGYMDPTYI--STNKYTMKSDIYSFGVIILELITAIHPQQNLMEYI 320
Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQ---LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
L S SP + Q + S + LA + ++C+ P +RPS + + + +++
Sbjct 321 NLASMSPDGIDEILD-QKLVGNASIEEVRLLAKIANRCVHKTPRKRPSIGEVTQFILKIK 379
>sp|P54645|AAPK1_RAT 5'-AMP-activated protein kinase catalytic
subunit alpha-1 OS=Rattus norvegicus OX=10116 GN=Prkaa1 PE=1
SV=2
Length=559
Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 72/201 (36%), Positives = 98/201 (49%), Gaps = 22/201 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957
LG G FGKV + ++ TG VAVK L + RS ++EI L+ H
Sbjct 33 LGVGTFGKVKV----GKHELTGHKVAVKILNRQ---KIRSLDVVGKIRREIQNLKLFRHP 85
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016
HIIK + + +VMEYV G L DY+ ++ + + QQI G+ Y H
Sbjct 86 HIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 143
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE +
Sbjct 144 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 198
Query 1077 KFYYA--SDVWSFGVTLYELL 1095
+ Y D+WS GV LY LL
Sbjct 199 RLYAGPEVDIWSSGVILYALL 219
>sp|O42632|KPC1_COCHE Protein kinase C-like OS=Cochliobolus heterostrophus
OX=5016 GN=PKC1 PE=3 SV=1
Length=1174
Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 58/198 (29%), Positives = 91/198 (46%), Gaps = 14/198 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957
LG+G+FGKV L T ++ A+K LK + ++ K+ I H
Sbjct 855 LGKGNFGKVML----AETKTTKQLYAIKVLKKEFIIENDEVESTRSEKRVFLIANKERHP 910
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
++ C Q E + VMEY+ G L ++ R G + +A ++C + Y H
Sbjct 911 FLLNLHACF--QTETRVYFVMEYISGGDLMLHIQRGQFGTKRAQFYAAEVCLALKYFHEN 968
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
I+RDL N++L D +K+ D+GL K E Y + APE L + K
Sbjct 969 GVIYRDLKLDNIMLTLDGHIKVADYGLCK---EEMWYGSTTSTFCGTPEFMAPEILLDKK 1025
Query 1078 FYYASDVWSFGVTLYELL 1095
+ A D W+FGV +Y++L
Sbjct 1026 YGRAVDWWAFGVLIYQML 1043
>sp|Q38772|CDC2A_ANTMA Cell division control protein 2 homolog
A OS=Antirrhinum majus OX=4151 GN=CDC2A PE=2 SV=2
Length=294
Score = 78.6 bits (192), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 64/208 (31%), Positives = 101/208 (49%), Gaps = 20/208 (10%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYH 956
+K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ + H
Sbjct 5 EKVEKIGEGTYGVV----YKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR--DYLPRHSIGLAQLLLFAQQICEGMAYL 1014
+I++ + EK L LV EY+ L + D P S + +F QI G+AY
Sbjct 61 GNIVRLQDVV--HSEKRLYLVFEYLDLDLKKHMDSCPEFSQDPRLVKMFLYQILRGIAYC 118
Query 1015 HAQHYIHRDLAARNVLLD-NDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070
H+ +HRDL +N+L+D +K+ DFGLA+A +P + V WY AP
Sbjct 119 HSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHEV------VTLWYRAP 172
Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTH 1097
E L + Y DVWS G E++
Sbjct 173 EILLGSRHYSTPVDVWSVGCIFAEMVNQ 200
>sp|Q9FJ55|CIPKJ_ARATH CBL-interacting serine/threonine-protein
kinase 19 OS=Arabidopsis thaliana OX=3702 GN=CIPK19 PE=1 SV=1
Length=483
Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 69/207 (33%), Positives = 103/207 (50%), Gaps = 26/207 (13%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYH 956
R LG G F KV Y N +GE VA+K + D +SG K+EI ILR + H
Sbjct 32 RLLGHGTFAKV----YLARNAQSGESVAIKVI--DKEKVLKSGLIAHIKREISILRRVRH 85
Query 957 EHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH 1015
+I++ E KS + VMEYV G L + + + + + QQ+ +++ H
Sbjct 86 PNIVQ---LFEVMATKSKIYFVMEYVKGGELFNKVAKGRLKEEMARKYFQQLISAVSFCH 142
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WYAP 1070
+ HRDL N+LLD + +K+ DFGL+ AV + ++R+DG F + AP
Sbjct 143 FRGVYHRDLKPENLLLDENGNLKVSDFGLS-AVSD-----QIRQDGLFHTFCGTPAYVAP 196
Query 1071 ECLKEYKFYYAS-DVWSFGVTLYELLT 1096
E L + A D+WS GV L+ L+
Sbjct 197 EVLARKGYDGAKVDIWSCGVILFVLMA 223
Score = 40.8 bits (94), Expect = 0.077, Method: Compositional matrix adjust.
Identities = 52/213 (24%), Positives = 90/213 (42%), Gaps = 22/213 (10%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S++ +V H ++ + V + V EYV+ G L + + R MA K QQL
Sbjct 78 SILRRVRHPNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAKGRLKEEMARKYF--QQLI 135
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776
SA+S+ + + H ++ N+LL G +K+SD GL A+S + R + +
Sbjct 136 SAVSFCHFRGVYHRDLKPENLLLDENG-------NLKVSD--FGLSAVSDQIRQDGLFHT 186
Query 777 -----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP-SEKEHFYQRQ 830
++APE L +D W G L + G P R+ + + Y+
Sbjct 187 FCGTPAYVAPEVLARKGYD-GAKVDIWSCGVILF-VLMAGFLPFHDRNVMAMYKKIYRGD 244
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
R P ++ L + L +P +R + I+
Sbjct 245 FRCPRWFPVEINRLLIRMLETKPERRFTMPDIM 277
>sp|Q5GIG6|TNI3K_MOUSE Serine/threonine-protein kinase TNNI3K
OS=Mus musculus OX=10090 GN=Tnni3k PE=2 SV=4
Length=834
Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 66/229 (29%), Positives = 112/229 (49%), Gaps = 18/229 (8%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
ADVL + + P+ + +I +G G FGKV ++VA+K +A
Sbjct 442 ADVLLLRAELPSRFHLQLSEIEFHEI--IGSGSFGKVY------KGRCRNKIVAIKRYRA 493
Query 935 D--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-- 990
+ C + +E+ IL L H ++++ G C D + +V +Y+ GSL L
Sbjct 494 NTYCSKSDVDMFCREVSILCQLNHPCVVQFVGACLDDPSQ-FAIVTQYISGGSLFSLLHE 552
Query 991 PRHSIGLAQLLLFAQQICEGMAYLHA--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ + L L+ A + +GM YLH+ Q IHRDL + N+LL D + DFG ++ +
Sbjct 553 QKRILDLQSKLIIAVDVAKGMEYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFL 612
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLT 1096
E ++ G+ + W APE + ++ +DV+S+ + L+ELLT
Sbjct 613 QSLDEDNMTKQPGN--LRWMAPEVFTQCTRYTIKADVFSYALCLWELLT 659
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 72/328 (22%), Positives = 127/328 (39%), Gaps = 67/328 (20%)
Query 557 ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616
E ++++++R S L LS++ FH + +G G+ VY+GR R
Sbjct 440 EKADVLLLRAELPSRFHLQLSEIEFHEI----------IGSGSFGKVYKGRCR------- 482
Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676
+ R R S D+ + F S++ Q++H + G
Sbjct 483 -------NKIVAIKRYRANTY--------CSKSDVDM-FCREVSILCQLNHPCVVQFVGA 526
Query 677 CVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN--KNLVHG 733
C+ P +VT+Y+ G L L ++ + + K+++A +A + YL + + ++H
Sbjct 527 CLDDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHSLTQPIIHR 586
Query 734 NVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALSREERVERIP----WLAPECLP 785
++ NILL G A G S F++ D E+ + + P W+APE
Sbjct 587 DLNSHNILLYEDGHAVVADFGESRFLQSLD----------EDNMTKQPGNLRWMAPEVFT 636
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH-------RLPEPSC 838
+ D + + L E+ GE P P+ H +P+P
Sbjct 637 -QCTRYTIKADVFSYALCLWEL-LTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPIS 694
Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDL 866
L + C P RP F ++R L
Sbjct 695 SLLMRGWNAC----PEGRPEFSEVVRKL 718
>sp|Q9ZWC8|BRL1_ARATH Serine/threonine-protein kinase BRI1-like
1 OS=Arabidopsis thaliana OX=3702 GN=BRL1 PE=1 SV=1
Length=1166
Score = 82.0 bits (201), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 84/286 (29%), Positives = 128/286 (45%), Gaps = 33/286 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG+V G +VA+K L G R + E++ + + H +++
Sbjct 865 VGSGGFGEVY-----KAQLRDGSVVAIKKLIRITGQGDRE-FMAEMETIGKIKHRNLVPL 918
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-------FAQQICEGMAYLH 1015
G C+ GE+ L LV EY+ GSL L S + L A G+A+LH
Sbjct 919 LGYCK-VGEERL-LVYEYMKWGSLETVLHEKSSKKGGIYLNWAARKKIAIGAARGLAFLH 976
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
H IHRD+ + NVLLD D ++ DFG+A+ V + V +P + PE
Sbjct 977 HSCIPHIIHRDMKSSNVLLDEDFEARVSDFGMARLVSALDTHLSVSTLAGTPGY-VPPEY 1035
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLE---LIGIAQGQMTVLRLTEL 1127
+ ++ DV+S+GV L ELL S + P P +F E L+G A+ R E+
Sbjct 1036 YQSFRCTAKGDVYSYGVILLELL----SGKKPIDPGEFGEDNNLVGWAKQLYREKRGAEI 1091
Query 1128 LERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170
L+ L E++H +K C + RPT L+ + K
Sbjct 1092 LD--PELVTDKSGDVELFHYLKIASQCLDDRPFKRPTMIQLMAMFK 1135
Score = 38.9 bits (89), Expect = 0.42, Method: Compositional matrix adjust.
Identities = 55/248 (22%), Positives = 100/248 (40%), Gaps = 55/248 (22%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---RRERGHVPMAW- 710
F + ++ H +L + G C G E ++V EY++ G L+ L ++G + + W
Sbjct 900 FMAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKWGSLETVLHEKSSKKGGIYLNWA 959
Query 711 -KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--L 764
+ +A A L++L + +++H ++ N+LL A ++SD G+ +
Sbjct 960 ARKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDEDFEA-------RVSDFGMARLV 1012
Query 765 GALSREERVERIP----WLAPE------CLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
AL V + ++ PE C G D + +G LLE+ G+ P
Sbjct 1013 SALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKG--------DVYSYGVILLEL-LSGKKP 1063
Query 815 LQSRSPSEKEHFY------QRQHRLPEPSCPQLAT-------------LTSQCLTYEPTQ 855
+ E + R+ R E P+L T + SQCL P +
Sbjct 1064 IDPGEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELFHYLKIASQCLDDRPFK 1123
Query 856 RPSFRTIL 863
RP+ ++
Sbjct 1124 RPTMIQLM 1131
>sp|Q8VDF3|DAPK2_MOUSE Death-associated protein kinase 2 OS=Mus
musculus OX=10090 GN=Dapk2 PE=1 SV=1
Length=370
Score = 79.7 bits (195), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 62/205 (30%), Positives = 100/205 (49%), Gaps = 20/205 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-----WKQEIDILRTLYH 956
+LG G F V C + + TG A K +K R G ++E+ ILR + H
Sbjct 28 ELGSGQFAIVK-KCREKS---TGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVLH 83
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLH 1015
+II E++ + + L++E V G L D+L + S+ + F +QI +G+ YLH
Sbjct 84 PNIITLHDVYENRTD--VVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLH 141
Query 1016 AQHYIHRDLAARNVLLDNDRL----VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
+ H DL N++L + + +K+ DFGLA + +G E+ + +P F APE
Sbjct 142 TKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNI---FGTPEF-VAPE 197
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
+ +D+WS GV Y LL+
Sbjct 198 IVNYEPLGLEADMWSIGVITYILLS 222
Score = 35.4 bits (80), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 42/171 (25%), Positives = 71/171 (42%), Gaps = 18/171 (11%)
Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQ 717
S++ QV H ++ +H V + +++ E V G L D ++E A + +Q
Sbjct 75 VSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFI--KQ 132
Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE--- 774
+ ++YL K + H ++ NI+L + P IKL D G+ A E+ VE
Sbjct 133 ILDGVNYLHTKKIAHFDLKPENIMLLDKNIP---IPHIKLIDFGL---AHEIEDGVEFKN 186
Query 775 ---RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
++APE + L D W G + I G +P + E
Sbjct 187 IFGTPEFVAPEIV--NYEPLGLEADMWSIGV-ITYILLSGASPFLGDTKQE 234
>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic
subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4
Length=559
Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 72/201 (36%), Positives = 98/201 (49%), Gaps = 22/201 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957
LG G FGKV + ++ TG VAVK L + RS ++EI L+ H
Sbjct 33 LGVGTFGKVKV----GKHELTGHKVAVKILNRQ---KIRSLDVVGKIRREIQNLKLFRHP 85
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016
HIIK + + +VMEYV G L DY+ ++ + + QQI G+ Y H
Sbjct 86 HIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 143
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE +
Sbjct 144 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 198
Query 1077 KFYYA--SDVWSFGVTLYELL 1095
+ Y D+WS GV LY LL
Sbjct 199 RLYAGPEVDIWSSGVILYALL 219
>sp|O35280|CHK1_MOUSE Serine/threonine-protein kinase Chk1 OS=Mus
musculus OX=10090 GN=Chek1 PE=1 SV=2
Length=476
Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 68/200 (34%), Positives = 98/200 (49%), Gaps = 13/200 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
++ LGEG +G+V L N T E VAVK + K+EI I + L HE++
Sbjct 12 VQTLGEGAYGEVQL----AVNRITEEAVAVKIVDMKRAIDCPENIKKEICINKMLSHENV 67
Query 960 IKYKGCCEDQGEKSLQ-LVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHA 1016
+K+ G + E +Q L +EY G L D + IG+ + F Q+ G+ YLH
Sbjct 68 VKFYG---HRREGHIQYLFLEYCSGGELFDRI-EPDIGMPEQDAQRFFHQLMAGVVYLHG 123
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
HRD+ N+LLD +KI DFGLA V + R+ + + APE LK
Sbjct 124 IGITHRDIKPENLLLDERDNLKISDFGLA-TVFRHNNRERLLNKMCGTLPYVAPELLKRK 182
Query 1077 KFYYA-SDVWSFGVTLYELL 1095
+F+ DVWS G+ L +L
Sbjct 183 EFHAEPVDVWSCGIVLTAML 202
>sp|F4I1N8|ATG1T_ARATH Serine/threonine-protein kinase ATG1t OS=Arabidopsis
thaliana OX=3702 GN=At1g49180 PE=2 SV=1
Length=408
Score = 80.1 bits (196), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 57/178 (32%), Positives = 90/178 (51%), Gaps = 11/178 (6%)
Query 923 TGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
TGE +K + R E++ L ++ H +II+ +D + L +V+EY
Sbjct 29 TGEEAVMKCFDLSKLNRNLRDCLNNELEFLSSVDHPNIIRLLHVSQD--DDFLVMVLEYC 86
Query 982 PLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLHAQHYIHRDLAARNVLLD---NDRLV 1037
G+L Y+ R+ + F +QI G+ +H H IHRDL N+L+D +D ++
Sbjct 87 DGGTLSSYIQRYGRVEEDIAKRFMKQIGAGLEIIHDNHIIHRDLKPENILIDGSGDDLVL 146
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
KI DF LA+ + G V SP F+ APE L+ ++ +D+WS G L+ELL
Sbjct 147 KIADFSLARKLHPGKYLETV---CGSP-FYMAPEVLQFQRYNEKADMWSVGAILFELL 200
>sp|Q5EG47|AAPK1_MOUSE 5'-AMP-activated protein kinase catalytic
subunit alpha-1 OS=Mus musculus OX=10090 GN=Prkaa1 PE=1 SV=2
Length=559
Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 72/201 (36%), Positives = 98/201 (49%), Gaps = 22/201 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957
LG G FGKV + ++ TG VAVK L + RS ++EI L+ H
Sbjct 33 LGVGTFGKVKV----GKHELTGHKVAVKILNRQ---KIRSLDVVGKIRREIQNLKLFRHP 85
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016
HIIK + + +VMEYV G L DY+ ++ + + QQI G+ Y H
Sbjct 86 HIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 143
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE +
Sbjct 144 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 198
Query 1077 KFYYA--SDVWSFGVTLYELL 1095
+ Y D+WS GV LY LL
Sbjct 199 RLYAGPEVDIWSSGVILYALL 219
>sp|Q5JLQ9|CIPKU_ORYSJ CBL-interacting protein kinase 30 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK30 PE=2 SV=1
Length=476
Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 75/227 (33%), Positives = 110/227 (48%), Gaps = 32/227 (14%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
++ + D V RY K R LG G F KV Y TGE VA+K D RS
Sbjct 4 ETTSQDSQVIMGRY-KLGRLLGRGTFAKV----YKAYKLATGEAVAIKVF--DKEAVQRS 56
Query 943 GW----KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSI 995
G K+E+D++R ++H H+I+ + + VMEY G L L PR
Sbjct 57 GTVEQVKREVDVMRRVHHRHVIRLHEVMATRSR--IYFVMEYASGGELFTRLSRSPRFPE 114
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+A+ + QQ+ + + H++ HRDL N+LLD +K+ DFGL+ A+ G
Sbjct 115 PVARR--YFQQLITAVEFCHSRGVYHRDLKPENLLLDARGDLKVTDFGLS-ALDGG---- 167
Query 1056 RVREDG------DSPVFWYAPECLKEYKFYYA-SDVWSFGVTLYELL 1095
+R DG +P + APE L + + A +D+WS GV L+ LL
Sbjct 168 -LRGDGLLHTTCGTPAY-VAPEVLLKRGYDGAKADIWSCGVILFVLL 212
>sp|P51952|CDK7_RAT Cyclin-dependent kinase 7 (Fragment) OS=Rattus
norvegicus OX=10116 GN=Cdk7 PE=1 SV=2
Length=329
Score = 79.0 bits (193), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 69/230 (30%), Positives = 109/230 (47%), Gaps = 26/230 (11%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ----EIDILRT 953
+K+ LGEG F V Y + T ++VA+K +K + + G + EI +L+
Sbjct 5 EKLDFLGEGQFATV----YKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQE 60
Query 954 LYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEG 1010
L H +II G + G KS + LV +++ L + +S+ L + + + +G
Sbjct 61 LSHPNII---GLLDAFGHKSNISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQG 116
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-A 1069
+ YLH +HRDL N+LLD + ++K+ DFGLAK+ + Y + WY A
Sbjct 117 LEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNWAYTHQ----VVTRWYRA 172
Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIG 1113
PE L + Y D+W+ G L ELL DS T+ E +G
Sbjct 173 PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLG 222
>sp|P10665|KS6AA_XENLA Ribosomal protein S6 kinase 2 alpha OS=Xenopus
laevis OX=8355 GN=rps6ka PE=1 SV=1
Length=733
Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 57/199 (29%), Positives = 105/199 (53%), Gaps = 8/199 (4%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEH 958
++ LG+G FGKV L T ++ A+K LK A + R K E DIL ++H
Sbjct 65 LKVLGQGSFGKVFL-VRKITPPDANQLYAMKVLKKATLKVRDRVRTKMERDILADVHHPF 123
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ-LLLFAQQICEGMAYLHAQ 1017
+++ + +G+ L L+++++ G L L + + + + + ++ G+ +LH+
Sbjct 124 VVRLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSL 181
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
I+RDL N+LLD + +K+ DFGL+K E ++ + V + APE +
Sbjct 182 GIIYRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKKAYSFCGTVEYMAPEVVNRQG 238
Query 1078 FYYASDVWSFGVTLYELLT 1096
+++D WS+GV ++E+LT
Sbjct 239 HSHSADWWSYGVLMFEMLT 257
Score = 59.7 bits (143), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 57/195 (29%), Positives = 90/195 (46%), Gaps = 32/195 (16%)
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKS 973
C + GT AVK + + + +EI+ILR H +II K ++ S
Sbjct 430 CKRCVHKGTNMEYAVKVID-----KTKRDPSEEIEILRRYGQHPNIIALKDVYKEGN--S 482
Query 974 LQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030
+ +V E + G L D + R S A +LF +C+ + LH+Q +HRDL N+L
Sbjct 483 IYVVTELMRGGELLDRILRQKFFSEREASSVLFT--VCKTVENLHSQGVVHRDLKPSNIL 540
Query 1031 LDND----RLVKIGDFGLAKAVPEGHEYYRVREDGD---SPVF---WYAPECLKEYKFYY 1080
++ ++I DFG AK ++R D +P + + APE LK +
Sbjct 541 YVDESGDPESIRICDFGFAK---------QLRADNGLLMTPCYTANFVAPEVLKRQGYDE 591
Query 1081 ASDVWSFGVTLYELL 1095
D+WS G+ LY +L
Sbjct 592 GCDIWSLGILLYTML 606
>sp|Q7TQP6|TNI3K_RAT Serine/threonine-protein kinase TNNI3K OS=Rattus
norvegicus OX=10116 GN=Tnni3k PE=2 SV=3
Length=835
Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 66/229 (29%), Positives = 112/229 (49%), Gaps = 18/229 (8%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
ADVL + + P+ + +I +G G FGKV ++VA+K +A
Sbjct 443 ADVLLLRAELPSRFHLQLSEIEFHEI--IGSGSFGKVY------KGRCRNKIVAIKRYRA 494
Query 935 D--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-- 990
+ C + +E+ IL L H ++++ G C D + +V +Y+ GSL L
Sbjct 495 NTYCSKSDVDMFCREVSILCQLNHPCVVQFVGACLDDPSQ-FAIVTQYISGGSLFSLLHE 553
Query 991 PRHSIGLAQLLLFAQQICEGMAYLHA--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ + L L+ A + +GM YLH+ Q IHRDL + N+LL D + DFG ++ +
Sbjct 554 QKRILDLQSKLIIAVDVAKGMEYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFL 613
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLT 1096
E ++ G+ + W APE + ++ +DV+S+ + L+ELLT
Sbjct 614 QSLDEDNMTKQPGN--LRWMAPEVFTQCTRYTIKADVFSYSLCLWELLT 660
Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 71/328 (22%), Positives = 126/328 (38%), Gaps = 67/328 (20%)
Query 557 ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616
E ++++++R S L LS++ FH + +G G+ VY+GR R
Sbjct 441 EKADVLLLRAELPSRFHLQLSEIEFHEI----------IGSGSFGKVYKGRCR------- 483
Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676
+ R R S D+ + F S++ Q++H + G
Sbjct 484 -------NKIVAIKRYRANTY--------CSKSDVDM-FCREVSILCQLNHPCVVQFVGA 527
Query 677 CVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN--KNLVHG 733
C+ P +VT+Y+ G L L ++ + + K+++A +A + YL + + ++H
Sbjct 528 CLDDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHSLTQPIIHR 587
Query 734 NVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALSREERVERIP----WLAPECLP 785
++ NILL G A G S F++ D E+ + + P W+APE
Sbjct 588 DLNSHNILLYEDGHAVVADFGESRFLQSLD----------EDNMTKQPGNLRWMAPEVFT 637
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH-------RLPEPSC 838
+ D + + L E+ GE P P+ H +P+P
Sbjct 638 -QCTRYTIKADVFSYSLCLWEL-LTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPIS 695
Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDL 866
L + C P RP F ++ L
Sbjct 696 SLLIRGWNAC----PEGRPEFSEVVSKL 719
>sp|O80939|LRK41_ARATH L-type lectin-domain containing receptor
kinase IV.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK41 PE=2
SV=1
Length=675
Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 67/201 (33%), Positives = 98/201 (49%), Gaps = 21/201 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---EIDILRTLYHEHI 959
LG G FG V Y GT +AVK + + R G K+ EI + + H ++
Sbjct 353 LGTGGFGSV----YKGVMPGTKLEIAVKRVSHES----RQGMKEFVAEIVSIGRMSHRNL 404
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA 1016
+ G C +GE L LV +Y+P GSL YL P ++ Q + + G+ YLH
Sbjct 405 VPLLGYCRRRGE--LLLVYDYMPNGSLDKYLYNTPEVTLNWKQRIKVILGVASGLFYLHE 462
Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
Q IHRD+ A NVLLD + ++GDFGLA+ G + G + + APE
Sbjct 463 EWEQVVIHRDVKASNVLLDGELNGRLGDFGLARLYDHGSDPQTTHVVG--TLGYLAPEHT 520
Query 1074 KEYKFYYASDVWSFGVTLYEL 1094
+ + A+DV++FG L E+
Sbjct 521 RTGRATMATDVFAFGAFLLEV 541
Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 51/185 (28%), Positives = 82/185 (44%), Gaps = 20/185 (11%)
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
G +L + +K + F + ++SH +L + G C R E ++V +Y+ +G
Sbjct 368 GTKLEIAVKRVSHESRQGMKEFVAEIVSIGRMSHRNLVPLLGYCRRRGELLLVYDYMPNG 427
Query 694 PLDVWLRRERGHVPMAWK--MVVAQQLASALSYLE---NKNLVHGNVCGRNILL-----A 743
LD +L V + WK + V +AS L YL + ++H +V N+LL
Sbjct 428 SLDKYLYNTP-EVTLNWKQRIKVILGVASGLFYLHEEWEQVVIHRDVKASNVLLDGELNG 486
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
RLG + SDP V + +LAPE G +++T D + FGA
Sbjct 487 RLGDFGLARLYDHGSDP-------QTTHVVGTLGYLAPEHTRTGRATMAT--DVFAFGAF 537
Query 804 LLEIC 808
LLE+
Sbjct 538 LLEVA 542
>sp|Q9SNA3|Y3463_ARATH Putative receptor-like protein kinase At3g46340
OS=Arabidopsis thaliana OX=3702 GN=At3g46340 PE=1 SV=1
Length=889
Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 61/204 (30%), Positives = 103/204 (50%), Gaps = 15/204 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LGEG FG V Y +G+ + VAVK L + Q +K E+++L ++H +++
Sbjct 589 RPLGEGGFGVV----YHGDINGSSQQVAVKLL-SQSSTQGYKEFKAEVELLLRVHHINLV 643
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQL---LLFAQQICEGMAYLHA 1016
G C+++ L L+ EY+ L+ +L +H + + L A G+ YLH
Sbjct 644 SLVGYCDERDH--LALIYEYMSNKDLKHHLSGKHGGSVLKWNTRLQIAVDAALGLEYLHI 701
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+HRD+ + N+LLD+ K+ DFGL+++ G E +P + PE
Sbjct 702 GCRPSMVHRDVKSTNILLDDQFTAKMADFGLSRSFQLGDESQVSTVVAGTPGY-LDPEYY 760
Query 1074 KEYKFYYASDVWSFGVTLYELLTH 1097
+ + SDV+SFG+ L E++T+
Sbjct 761 RTGRLAEMSDVYSFGIVLLEIITN 784
Score = 41.6 bits (96), Expect = 0.055, Method: Compositional matrix adjust.
Identities = 50/189 (26%), Positives = 77/189 (41%), Gaps = 20/189 (11%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G G +V +K+L S F L+ +V H +L + G C ++ EY
Sbjct 602 GDINGSSQQVAVKLLSQSSTQGYKEFKAEVELLLRVHHINLVSLVGYCDERDHLALIYEY 661
Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLAR 744
+ + L L + G + W ++ +A A L YL ++VH +V NILL
Sbjct 662 MSNKDLKHHLSGKHGGSVLKWNTRLQIAVDAALGLEYLHIGCRPSMVHRDVKSTNILLDD 721
Query 745 LGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP-----WLAPECLPGGANSLSTAMDKW 798
A K++D G+ L E +V + +L PE G L+ D +
Sbjct 722 QFTA-------KMADFGLSRSFQLGDESQVSTVVAGTPGYLDPEYYRTG--RLAEMSDVY 772
Query 799 GFGATLLEI 807
FG LLEI
Sbjct 773 SFGIVLLEI 781
>sp|O43293|DAPK3_HUMAN Death-associated protein kinase 3 OS=Homo
sapiens OX=9606 GN=DAPK3 PE=1 SV=1
Length=454
Score = 80.5 bits (197), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 62/205 (30%), Positives = 102/205 (50%), Gaps = 20/205 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-----WKQEIDILRTLYH 956
+LG G F V C GTG+ A K +K R G ++E++ILR + H
Sbjct 18 ELGSGQFAIVR-KC---RQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRH 73
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLH 1015
+II E++ + + L++E V G L D+L + S+ + F +QI +G+ YLH
Sbjct 74 PNIITLHDIFENKTD--VVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131
Query 1016 AQHYIHRDLAARNVLLDNDRL----VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
++ H DL N++L + + +K+ DFG+A + G+E+ + +P F APE
Sbjct 132 SKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNI---FGTPEF-VAPE 187
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
+ +D+WS GV Y LL+
Sbjct 188 IVNYEPLGLEADMWSIGVITYILLS 212
>sp|Q19469|SAD1_CAEEL Serine/threonine kinase SAD-1 OS=Caenorhabditis
elegans OX=6239 GN=sad-1 PE=1 SV=2
Length=914
Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 63/200 (32%), Positives = 97/200 (49%), Gaps = 17/200 (9%)
Query 901 RDLGEGHFG--KVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHE 957
+ LG+G G K +C TG VA+K + K ++EI I++ + H
Sbjct 51 KTLGKGQTGLVKTGTHCI------TGRKVAIKIVNKEKLSESVLQKVEREIAIMKLIEHP 104
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA-QLLLFAQQICEGMAYLHA 1016
H++ E++ K L L++E+V G L DYL R ++ + F +QI + + HA
Sbjct 105 HVLHLYDVYENK--KYLYLLLEHVSGGELFDYLVRKGRLMSKEARKFFRQIISALDFCHA 162
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ HRDL N+LLD +K+ DFG+A EG + E + PE ++
Sbjct 163 HNICHRDLKPENLLLDERNNIKVADFGMASLQVEGS----MLETSCGSPHYACPEVIRGE 218
Query 1077 KFY-YASDVWSFGVTLYELL 1095
K+ +DVWS GV LY LL
Sbjct 219 KYDGRKADVWSCGVILYALL 238
>sp|Q68UT7|HUNK_PANTR Hormonally up-regulated neu tumor-associated
kinase OS=Pan troglodytes OX=9598 GN=HUNK PE=3 SV=1
Length=714
Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 68/213 (32%), Positives = 98/213 (46%), Gaps = 18/213 (8%)
Query 893 HKR---YLKKIRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKAL---KADCGPQHRSGW 944
HKR YL R LGEG F KV L+ TGE VA+K + +A
Sbjct 55 HKRVGNYLIGSRKLGEGSFAKVREGLHVL------TGEKVAIKVIDKKRAKKDTYVTKNL 108
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLF 1003
++E I + + H +I + E E S LVME P G+L + + + ++ +
Sbjct 109 RREGQIQQMIRHPNITQLLDILET--ENSYYLVMELCPGGNLMHKIYEKKRLEESEARRY 166
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+Q+ + +LH +HRDL N+LLD D +K+ DFGL+ S
Sbjct 167 IRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGS 226
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
P + APE L K+ DVWS GV +Y +LT
Sbjct 227 PAYA-APELLARKKYGPKIDVWSIGVNMYAMLT 258
>sp|Q9Y572|RIPK3_HUMAN Receptor-interacting serine/threonine-protein
kinase 3 OS=Homo sapiens OX=9606 GN=RIPK3 PE=1 SV=2
Length=518
Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 83/297 (28%), Positives = 135/297 (45%), Gaps = 36/297 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FG V + + G VAVK + + +E+ + +L +E +++
Sbjct 27 VGKGGFGTV----FRAQHRKWGYDVAVKIVNSKA-------ISREVKAMASLDNEFVLRL 75
Query 963 KGCCE----DQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYL 1014
+G E DQ K LV +++ GSL L PR L +LL +++ GM YL
Sbjct 76 EGVIEKVNWDQDPKPA-LVTKFMENGSLSGLLQSQCPRPWPLLCRLL---KEVVLGMFYL 131
Query 1015 HAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
H Q+ +HRDL NVLLD + VK+ DFGL+ E G + + + APE
Sbjct 132 HDQNPVLLHRDLKPSNVLLDPELHVKLADFGLSTFQGGSQSGTGSGEPGGT-LGYLAPEL 190
Query 1073 LKEY--KFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLTELLE 1129
K ASDV+SFG+ ++ +L + + P+ E + Q + + L EL +
Sbjct 191 FVNVNRKASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAVCNRQNRPS---LAELPQ 247
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
G P + + LM+ CW +E RP+F+ +P V + + + S
Sbjct 248 AGPETPGLEG----LKELMQLCWSSEPKDRPSFQECLPKTDEVFQMVENNMNAAVST 300
Score = 43.5 bits (101), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 61/251 (24%), Positives = 106/251 (42%), Gaps = 51/251 (20%)
Query 649 HDIALAFYETASL------MSQVSHTHLAFVHGVCVR-----GPENIMVTEYVEHGPLDV 697
+D+A+ + ++ M+ + + + + GV + P+ +VT+++E+G L
Sbjct 45 YDVAVKIVNSKAISREVKAMASLDNEFVLRLEGVIEKVNWDQDPKPALVTKFMENGSLSG 104
Query 698 WLRRERGHVPMAWKMV--VAQQLASALSYLENKN--LVHGNVCGRNILLA---RLGLAE- 749
L+ + P W ++ + +++ + YL ++N L+H ++ N+LL + LA+
Sbjct 105 LLQSQ---CPRPWPLLCRLLKEVVLGMFYLHDQNPVLLHRDLKPSNVLLDPELHVKLADF 161
Query 750 GTSPFIKLS-------DPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
G S F S +PG LG +LAPE STA D + FG
Sbjct 162 GLSTFQGGSQSGTGSGEPGGTLG------------YLAPELFVNVNRKASTASDVYSFGI 209
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHR-----LPE-----PSCPQLATLTSQCLTYE 852
+ + E L + E RQ+R LP+ P L L C + E
Sbjct 210 LMWAVLAGREVELPTEPSLVYEAVCNRQNRPSLAELPQAGPETPGLEGLKELMQLCWSSE 269
Query 853 PTQRPSFRTIL 863
P RPSF+ L
Sbjct 270 PKDRPSFQECL 280
>sp|P18265|GSK3A_RAT Glycogen synthase kinase-3 alpha OS=Rattus
norvegicus OX=10116 GN=Gsk3a PE=1 SV=1
Length=483
Score = 80.5 bits (197), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 70/211 (33%), Positives = 103/211 (49%), Gaps = 33/211 (16%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I+ +G G FG V Y T E+VA+K + D ++R E+ I+R L H +I
Sbjct 122 IKVIGNGSFGVV----YQARLAETRELVAIKKVLQDKRFKNR-----ELQIMRKLDHCNI 172
Query 960 IKYKGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRH------SIGLAQLLLFAQQICE 1009
++ + GEK L LV+EYVP R + RH I + + ++ Q+
Sbjct 173 VRLRYFFYSSGEKKDELYLNLVLEYVPETVYR--VARHFTKAKLIIPIIYVKVYMYQLFR 230
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGH---EYYRVREDGDSPV 1065
+AY+H+Q HRD+ +N+L+D D V K+ DFG AK + G Y R
Sbjct 231 SLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR------- 283
Query 1066 FWYAPECLKEYKFYYAS-DVWSFGVTLYELL 1095
++ APE + Y +S DVWS G L ELL
Sbjct 284 YYRAPELIFGATDYTSSIDVWSAGCVLAELL 314
Score = 36.2 bits (82), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 31/128 (24%), Positives = 59/128 (46%), Gaps = 12/128 (9%)
Query 685 MVTEYVEHGPLDVW--LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+V EYV V + + +P+ + V QL +L+Y+ ++ + H ++ +N+L+
Sbjct 193 LVLEYVPETVYRVARHFTKAKLIIPIIYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLV 252
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWG 799
+ + +KL D G + E V I + APE + GA ++++D W
Sbjct 253 ------DPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELI-FGATDYTSSIDVWS 305
Query 800 FGATLLEI 807
G L E+
Sbjct 306 AGCVLAEL 313
>sp|Q5RDH5|AAPK1_PONAB 5'-AMP-activated protein kinase catalytic
subunit alpha-1 (Fragment) OS=Pongo abelii OX=9601 GN=PRKAA1
PE=2 SV=2
Length=554
Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 72/201 (36%), Positives = 98/201 (49%), Gaps = 22/201 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957
LG G FGKV + ++ TG VAVK L + RS ++EI L+ H
Sbjct 28 LGVGTFGKVKV----GKHELTGHKVAVKILNRQ---KIRSLDVVGKIRREIQNLKLFRHP 80
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016
HIIK + + +VMEYV G L DY+ ++ + + QQI G+ Y H
Sbjct 81 HIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 138
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE +
Sbjct 139 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 193
Query 1077 KFYYA--SDVWSFGVTLYELL 1095
+ Y D+WS GV LY LL
Sbjct 194 RLYAGPEVDIWSSGVILYALL 214
>sp|Q41639|CDC2_VIGAC Cell division control protein 2 homolog
OS=Vigna aconitifolia OX=3918 GN=CDC2 PE=2 SV=1
Length=294
Score = 78.2 bits (191), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 64/207 (31%), Positives = 101/207 (49%), Gaps = 20/207 (10%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYH 956
+K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ + H
Sbjct 5 EKVEKIGEGTYGVV----YKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR--DYLPRHSIGLAQLLLFAQQICEGMAYL 1014
+I++ + EK L LV EY+ L + D P Q+ +F QI G+AY
Sbjct 61 RNIVRLQDVV--HSEKRLYLVFEYLDLDLKKHMDSSPEFVKDPRQVKMFLYQILCGIAYC 118
Query 1015 HAQHYIHRDLAARNVLLD-NDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070
H+ +HRDL +N+L+D +K+ DFGLA+A +P + V WY AP
Sbjct 119 HSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEV------VTLWYRAP 172
Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLT 1096
E L + Y DVWS G E++
Sbjct 173 EILLGSRHYSTPVDVWSVGCIFAEMVN 199
>sp|P53349|M3K1_MOUSE Mitogen-activated protein kinase kinase
kinase 1 OS=Mus musculus OX=10090 GN=Map3k1 PE=1 SV=3
Length=1493
Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 64/243 (26%), Positives = 119/243 (49%), Gaps = 23/243 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDP--TVFHKRYLK-----KIRDLGEGHFGKVSLYCYDPTN 920
+LQ N D++ + D+P + P T + Y + K + +G G F CY +
Sbjct 1188 QLQVENGEDIIIIQQDTPETLPGHTKAKQPYREDAEWLKGQQIGLGAFSS----CYQAQD 1243
Query 921 DGTGEMVAVKAL---KADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGC-CEDQGEKSL 974
GTG ++AVK + + Q ++EI ++ L H +II+ G CE + +
Sbjct 1244 VGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMGHLNHPNIIRMLGATCE---KSNY 1300
Query 975 QLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033
L +E++ GS+ L ++ +++ + +Q+ G++YLH IHRD+ N+L+D+
Sbjct 1301 NLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDS 1360
Query 1034 D-RLVKIGDFG-LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091
+ ++I DFG A+ +G + + + APE L+ ++ + DVWS G +
Sbjct 1361 TGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAI 1420
Query 1092 YEL 1094
E+
Sbjct 1421 IEM 1423
Score = 47.8 bits (112), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 49/226 (22%), Positives = 90/226 (40%), Gaps = 14/226 (6%)
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
++ A E +M ++H ++ + G + E++ G + L + G
Sbjct 1265 QEEVVEALREEIRMMGHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSV-AHLLSKYGAFK 1323
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF---IKLSDPGVGL 764
+ + +QL LSYL ++H +V G N+L+ G + F +L+ G G
Sbjct 1324 ESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGA 1383
Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE-- 822
G + + + I ++APE L G + D W G ++E+ + P + S
Sbjct 1384 GEF-QGQLLGTIAFMAPEVLRG--QQYGRSCDVWSVGCAIIEMAC-AKPPWNAEKHSNHL 1439
Query 823 ----KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
K +P P L + +CL +P RP R +L+
Sbjct 1440 ALIFKIASATTAPSIPSHLSPGLRDVAVRCLELQPQDRPPSRELLK 1485
>sp|Q753D9|PKH3_EREGS Serine/threonine-protein kinase PKH3 OS=Eremothecium
gossypii (strain ATCC 10895 / CBS 109.51 / FGSC
9923 / NRRL Y-1056) OX=284811 GN=PKH3 PE=3 SV=1
Length=726
Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 55/159 (35%), Positives = 76/159 (48%), Gaps = 14/159 (9%)
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLF 1003
K +++L H IIK DQ ++L VM+ P G L L R + A +
Sbjct 59 KNTLNLLGQANHPGIIKLYYTFHDQ--ENLYFVMDLAPGGELLQLLRRQRVFSEAWARHY 116
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
Q+ + + Y+H+ IHRDL NVLLD + + I DFG A V + DGD
Sbjct 117 MCQLVDTVEYIHSMGVIHRDLKPENVLLDKEGRLMIADFGAAYTVGQSD----AGSDGDK 172
Query 1064 PVF-------WYAPECLKEYKFYYASDVWSFGVTLYELL 1095
P + +PE L E K YY+SDVW+ G LY+ L
Sbjct 173 PATSFVGTAEYVSPELLLENKSYYSSDVWALGCMLYQFL 211
Score = 41.6 bits (96), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 53/214 (25%), Positives = 90/214 (42%), Gaps = 12/214 (6%)
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715
T +L+ Q +H + ++ EN+ V + G L LRR+R AW
Sbjct 60 NTLNLLGQANHPGIIKLY-YTFHDQENLYFVMDLAPGGELLQLLRRQRV-FSEAWARHYM 117
Query 716 QQLASALSYLENKNLVHGNVCGRNILL---ARLGLAE-GTSPFIKLSDPGVGLGALSREE 771
QL + Y+ + ++H ++ N+LL RL +A+ G + + SD G G
Sbjct 118 CQLVDTVEYIHSMGVIHRDLKPENVLLDKEGRLMIADFGAAYTVGQSDAGSD-GDKPATS 176
Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQ 830
V +++PE L + S+ D W G L + G P + ++ E E
Sbjct 177 FVGTAEYVSPELLLENKSYYSS--DVWALGCMLYQF-LQGTPPFRGQNEMETFEQIVNLD 233
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ P+ P A L S+ L +P+QR + I +
Sbjct 234 YTWRIPANPLAAGLVSKILVLDPSQRYTLEQIKK 267
>sp|Q2V419|CKB12_ARATH Cyclin-dependent kinase B1-2 OS=Arabidopsis
thaliana OX=3702 GN=CDKB1-2 PE=1 SV=2
Length=311
Score = 78.6 bits (192), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 68/222 (31%), Positives = 104/222 (47%), Gaps = 35/222 (16%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH-----------RSGWKQ 946
+K+ +GEG +GKV Y TG++VA+K + + + Q
Sbjct 5 EKLEKVGEGTYGKV----YKAMEKTTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSQ 60
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIG--------- 996
I I+R L EH+I+ K KS L LV EY+ L+ ++ H G
Sbjct 61 SIYIVRLLCVEHVIQSKDSTVSHSPKSNLYLVFEYLD-TDLKKFIDSHRKGSNPRPLEAS 119
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR-LVKIGDFGLAKAVPEGHEYY 1055
L Q +F Q+ +G+A+ H+ +HRDL +N+LLD D+ ++KI D GL++A + Y
Sbjct 120 LVQRFMF--QLFKGVAHCHSHGVLHRDLKPQNLLLDKDKGILKIADLGLSRAFTVPLKAY 177
Query 1056 RVREDGDSPVFWY-APECLKEYKFY-YASDVWSFGVTLYELL 1095
+ WY APE L Y A D+WS G E++
Sbjct 178 ----THEIVTLWYRAPEVLLGSTHYSTAVDIWSVGCIFAEMI 215
>sp|Q9XEC8|CRK38_ARATH Cysteine-rich receptor-like protein kinase
38 OS=Arabidopsis thaliana OX=3702 GN=CRK38 PE=3 SV=1
Length=648
Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 69/202 (34%), Positives = 101/202 (50%), Gaps = 18/202 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FG V Y G GE +AVK L G Q ++ E+ +L L H +++K
Sbjct 345 IGQGGFGSV----YKGKLPG-GEEIAVKRLTRGSG-QGEIEFRNEVLLLTRLQHRNLVKL 398
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA----YLHAQ- 1017
G C ++G++ + LV E+VP SL ++ L +I EG+A YLH
Sbjct 399 LGFC-NEGDEEI-LVYEFVPNSSLDHFIFDEEKRLLLTWDMRARIIEGVARGLVYLHEDS 456
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074
IHRDL A N+LLD K+ DFG+A+ R+ + F Y APE ++
Sbjct 457 QLRIIHRDLKASNILLDAYMNPKVADFGMARLFNMDQTRAVTRKVVGT--FGYMAPEYVR 514
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
F +DV+SFGV L E++T
Sbjct 515 NRTFSVKTDVYSFGVVLLEMIT 536
Score = 51.6 bits (122), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 55/215 (26%), Positives = 96/215 (45%), Gaps = 32/215 (15%)
Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663
+E ++ G G +GK+ PG G+E+ V K L + F L++
Sbjct 341 FENKIGQGGFGSVYKGKL-------PG---GEEIAV--KRLTRGSGQGEIEFRNEVLLLT 388
Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM--VVAQQLASA 721
++ H +L + G C G E I+V E+V + LD ++ E + + W M + + +A
Sbjct 389 RLQHRNLVKLLGFCNEGDEEILVYEFVPNSSLDHFIFDEEKRLLLTWDMRARIIEGVARG 448
Query 722 LSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERVER-- 775
L YL + ++H ++ NILL +P K++D G+ L + + V R
Sbjct 449 LVYLHEDSQLRIIHRDLKASNILLDAY-----MNP--KVADFGMARLFNMDQTRAVTRKV 501
Query 776 ---IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
++APE + + S D + FG LLE+
Sbjct 502 VGTFGYMAPEYVRN--RTFSVKTDVYSFGVVLLEM 534
>sp|Q9SA72|Y1357_ARATH Probable receptor-like protein kinase At1g30570
OS=Arabidopsis thaliana OX=3702 GN=At1g30570 PE=3 SV=1
Length=849
Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 80/282 (28%), Positives = 128/282 (45%), Gaps = 26/282 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHEHI 959
+G G FGKV DGT ++A+K P + G ++ EI +L L H H+
Sbjct 526 IGVGGFGKV---YRGELEDGT--LIAIKR----ATPHSQQGLAEFETEIVMLSRLRHRHL 576
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI---GLAQLLLFAQQICEGMAYLHA 1016
+ G C++ E + LV EY+ G+LR +L ++ Q L G+ YLH
Sbjct 577 VSLIGFCDEHNE--MILVYEYMANGTLRSHLFGSNLPPLSWKQRLEACIGSARGLHYLHT 634
Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ IHRD+ N+LLD + + K+ DFGL+KA P ++ V + PE
Sbjct 635 GSERGIIHRDVKTTNILLDENFVAKMSDFGLSKAGPS-MDHTHVSTAVKGSFGYLDPEYF 693
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ + SDV+SFGV L+E + C + PT + I +A+ ++ + L +
Sbjct 694 RRQQLTEKSDVYSFGVVLFEAV--CARAVINPTLPKDQINLAEWALSWQKQRNLESIIDS 751
Query 1134 LPRPDKCP--CEVY-HLMKNCWETEASFRPTFENLIPILKTV 1172
R + P E Y + + C E RP ++ L+ V
Sbjct 752 NLRGNYSPESLEKYGEIAEKCLADEGKNRPMMGEVLWSLEYV 793
Score = 45.4 bits (106), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 66/258 (26%), Positives = 105/258 (41%), Gaps = 46/258 (18%)
Query 648 HHDIALAFYETASLM-SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
H LA +ET +M S++ H HL + G C E I+V EY+ +G L R H+
Sbjct 553 HSQQGLAEFETEIVMLSRLRHRHLVSLIGFCDEHNEMILVYEYMANGTL-------RSHL 605
Query 707 ------PMAWKMVVAQQLASA--LSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFI 755
P++WK + + SA L YL + ++H +V NILL +A+ + +
Sbjct 606 FGSNLPPLSWKQRLEACIGSARGLHYLHTGSERGIIHRDVKTTNILLDENFVAKMSDFGL 665
Query 756 KLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE-ICFDGEAP 814
+ P + +S + +L PE L+ D + FG L E +C A
Sbjct 666 SKAGPSMDHTHVSTAVK-GSFGYLDPEYFR--RQQLTEKSDVYSFGVVLFEAVC--ARAV 720
Query 815 LQSRSPSEKEHF------YQRQHRL-------------PEPSCPQLATLTSQCLTYEPTQ 855
+ P ++ + +Q+Q L PE S + + +CL E
Sbjct 721 INPTLPKDQINLAEWALSWQKQRNLESIIDSNLRGNYSPE-SLEKYGEIAEKCLADEGKN 779
Query 856 RPSFRTILRDLTR-LQPH 872
RP +L L LQ H
Sbjct 780 RPMMGEVLWSLEYVLQIH 797
>sp|P18652|KS6AA_CHICK Ribosomal protein S6 kinase 2 alpha OS=Gallus
gallus OX=9031 GN=RPS6KA PE=2 SV=1
Length=752
Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 63/219 (29%), Positives = 112/219 (51%), Gaps = 13/219 (6%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGP 938
V S +DP+ F + ++ LG+G FGKV L T + + A+K LK A
Sbjct 68 VKEGSEKADPSQF-----ELLKVLGQGSFGKVFL-VRKITPPDSNHLYAMKVLKKATLKV 121
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA 998
+ R K E DIL + H ++K + +G+ L L+++++ G L L + +
Sbjct 122 RDRVRTKIERDILADVNHPFVVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTE 179
Query 999 Q-LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ + + ++ G+ +LH+ I+RDL N+LLD + +K+ DFGL+K E ++ +
Sbjct 180 EDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKK 236
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
V + APE + +++D WS+GV ++E+LT
Sbjct 237 AYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLT 275
Score = 66.2 bits (160), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 60/189 (32%), Positives = 87/189 (46%), Gaps = 23/189 (12%)
Query 946 QEIDIL-RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLF 1003
+EI+IL R H +II K +D K + LV E + G L D + R +
Sbjct 475 EEIEILLRYGQHPNIITLKDVYDDG--KYVYLVTELMRGGELLDKILRQKFFSEREASSV 532
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
IC+ + YLH+Q +HRDL N+L N ++I DFG AK + E
Sbjct 533 LHTICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRA--------E 584
Query 1060 DG--DSPVF---WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LI 1112
+G +P + + APE LK + D+WS GV LY +L C + P+ E L
Sbjct 585 NGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILT 644
Query 1113 GIAQGQMTV 1121
I G+ +V
Sbjct 645 RIGGGKFSV 653
>sp|Q8BZN4|NUAK2_MOUSE NUAK family SNF1-like kinase 2 OS=Mus musculus
OX=10090 GN=Nuak2 PE=1 SV=2
Length=639
Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 70/239 (29%), Positives = 108/239 (45%), Gaps = 26/239 (11%)
Query 874 LADVLTVNPDSPASDPTV---FHKRYLKK----IRDLGEGHFGKVSLYCYDPTNDGTGEM 926
LAD L +P V HK L+ + LG+G +GKV + +G +
Sbjct 27 LADGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVK-----KARESSGRL 81
Query 927 VAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCED------QGEKSLQLVM 978
VA+K+++ D Q ++EI+I+ +L H HII + + +VM
Sbjct 82 VAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVGRSRLVTVFENSSKIVIVM 141
Query 979 EYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037
EY G L DY+ R + F +QI + Y H +HRDL N+LLD + +
Sbjct 142 EYASRGDLYDYISERPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNI 201
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELL 1095
KI DFGL+ H+ ++ SP++ +PE + + D WS GV LY L+
Sbjct 202 KIADFGLSNLY---HKGKFLQTFCGSPLY-ASPEIVNGKPYVGPEVDSWSLGVLLYILV 256
Score = 35.8 bits (81), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 46/167 (28%), Positives = 69/167 (41%), Gaps = 23/167 (14%)
Query 661 LMSQVSHTHLAFVHGV----CVRGPEN----IMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
+MS ++H H+ +H V V EN ++V EY G L ++ ER +
Sbjct 107 IMSSLNHPHIIAIHEVGRSRLVTVFENSSKIVIVMEYASRGDLYDYIS-ERPRLSERDAR 165
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
+Q+ SAL Y +VH ++ NILL A G IK++D GL L + +
Sbjct 166 HFFRQIVSALHYCHQNGIVHRDLKLENILLD----ANGN---IKIAD--FGLSNLYHKGK 216
Query 773 VERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
+ P A + G + +D W G LL I G P
Sbjct 217 FLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLG-VLLYILVHGTMPF 262
>sp|P57058|HUNK_HUMAN Hormonally up-regulated neu tumor-associated
kinase OS=Homo sapiens OX=9606 GN=HUNK PE=1 SV=1
Length=714
Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 68/213 (32%), Positives = 98/213 (46%), Gaps = 18/213 (8%)
Query 893 HKR---YLKKIRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKAL---KADCGPQHRSGW 944
HKR YL R LGEG F KV L+ TGE VA+K + +A
Sbjct 55 HKRVGNYLIGSRKLGEGSFAKVREGLHVL------TGEKVAIKVIDKKRAKKDTYVTKNL 108
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLF 1003
++E I + + H +I + E E S LVME P G+L + + + ++ +
Sbjct 109 RREGQIQQMIRHPNITQLLDILET--ENSYYLVMELCPGGNLMHKIYEKKRLEESEARRY 166
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+Q+ + +LH +HRDL N+LLD D +K+ DFGL+ S
Sbjct 167 IRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGS 226
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
P + APE L K+ DVWS GV +Y +LT
Sbjct 227 PAYA-APELLARKKYGPKIDVWSIGVNMYAMLT 258
>sp|Q75V57|SAPK9_ORYSJ Serine/threonine-protein kinase SAPK9 OS=Oryza
sativa subsp. japonica OX=39947 GN=SAPK9 PE=1 SV=1
Length=361
Score = 79.3 bits (194), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 74/222 (33%), Positives = 109/222 (49%), Gaps = 24/222 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
++++G G+FG L N +G++VAVK + D G + ++EI R+L H +I
Sbjct 25 VKEIGSGNFGVARLM----RNRASGDLVAVKYI--DRGEKIDENVQREIINHRSLRHPNI 78
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA 1016
I++K L +VMEY G L + + R S A+ F QQ+ G++Y H+
Sbjct 79 IRFKEVI--LTPTHLAIVMEYASGGELFERICSAGRFSEDEARF--FFQQLISGVSYCHS 134
Query 1017 QHYIHRDLAARNVLLDNDRL--VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL- 1073
HRDL N LLD +KI DFG +K+ + + + +P + APE L
Sbjct 135 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKS---SVLHSQPKSTVGTPA-YIAPEVLL 190
Query 1074 -KEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLELI 1112
KEY A DVWS GVTLY +L + P P F + I
Sbjct 191 KKEYDGKIA-DVWSCGVTLYVMLVGAYPFEDPEDPKNFRKTI 231
>sp|Q7Z2Y5|NRK_HUMAN Nik-related protein kinase OS=Homo sapiens
OX=9606 GN=NRK PE=1 SV=2
Length=1582
Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 76/301 (25%), Positives = 132/301 (44%), Gaps = 56/301 (19%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-------------QHRSGWK-- 945
+ +G G +G++ L ++ TG AVK + A P Q GW+
Sbjct 29 KTIGLGTYGRIYLGLHE----KTGAFTAVKVMNARKTPLPEIGRRVRVNKYQKSVGWRYS 84
Query 946 -------QEIDILRTL-YHEHIIKYKGC---CEDQGEK-SLQLVMEYVPLGSLRDYL--- 990
E+++LR +H++I+ + G G++ L +VME GS+ D +
Sbjct 85 DEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPGQRHQLWMVMELCAAGSVTDVVRMT 144
Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
S+ + ++I +G+A+LHA IHRD+ +NVLL ++ VK+ DFG++ V
Sbjct 145 SNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKGQNVLLTHNAEVKLVDFGVSAQVSR 204
Query 1051 GHEYYRVREDGDSPVFWYAPECLK-----EYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ R +W APE + + Y SDVWS G+T E+ + +PP
Sbjct 205 TNGR---RNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDVWSVGITAIEM-----AEGAPP 256
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L+ + + +LR + + R + ++ M+ C FRPT N+
Sbjct 257 LCNLQPL---EALFVILRESAPTVKSSGWSR------KFHNFMEKCTIKNFLFRPTSANM 307
Query 1166 I 1166
+
Sbjct 308 L 308
Score = 37.4 bits (85), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 49/200 (25%), Positives = 76/200 (38%), Gaps = 29/200 (15%)
Query 632 DRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTH-LAFVHGVCVRGPENIMVTEY 689
D ++LR L +L S H ++FY +S H L V +C G VT
Sbjct 85 DEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPGQRHQLWMVMELCAAG----SVT-- 138
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
DV + W + +++ L++L ++H ++ G+N+LL
Sbjct 139 ------DVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKGQNVLLTH----- 187
Query 750 GTSPFIKLSDPGVGLGALSREERVERIP----WLAPE---CLPGGANSLSTAMDKWGFGA 802
+ +KL D GV R W+APE C S D W G
Sbjct 188 --NAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDVWSVGI 245
Query 803 TLLEICFDGEAPLQSRSPSE 822
T +E+ +G PL + P E
Sbjct 246 TAIEMA-EGAPPLCNLQPLE 264
>sp|O08644|EPHB6_MOUSE Ephrin type-B receptor 6 OS=Mus musculus
OX=10090 GN=Ephb6 PE=2 SV=4
Length=1014
Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 73/290 (25%), Positives = 131/290 (45%), Gaps = 36/290 (12%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DPT Y+K +G G FG+V P + VA++AL A + +
Sbjct 659 DPT-----YIKIEEVIGAGSFGEVRRGRLQPRGRRE-QAVAIQALWAGGAESLKMTFLGR 712
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ- 1006
+L H +I++ +G + + ++ E + LG L +L + + L L A Q
Sbjct 713 AALLGQFQHPNILRLEGVVTK--SRPVMVLTELMELGPLDSFLRQREGQFSSLQLVAMQR 770
Query 1007 -ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
+ M YL + ++HR L+AR+VL+++ + K+ G + P+G S +
Sbjct 771 GVAAAMQYLSSFAFVHRALSARSVLVNSHLVCKVARLGHS---PQGS---------SSLL 818
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
W APE + K+ +SDVWSFG+ ++E++++ + M +
Sbjct 819 RWAAPEVITHGKYTTSSDVWSFGILMWEVMSYGER--------------PYWDMNEQEVL 864
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+E+ RLP P CP ++ LM + W+ + + RP F+ L+ + K
Sbjct 865 NAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRK 914
Score = 65.5 bits (158), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 50/212 (24%), Positives = 94/212 (44%), Gaps = 32/212 (15%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
R R ++ + + + + F A+L+ Q H ++ + GV + +++TE +
Sbjct 685 RGRREQAVAIQALWAGGAESLKMTFLGRAALLGQFQHPNILRLEGVVTKSRPVMVLTELM 744
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL--------L 742
E GPLD +LR+ G + + + +A+A+ YL + VH + R++L +
Sbjct 745 ELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRALSARSVLVNSHLVCKV 804
Query 743 ARLGLA-EGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
ARLG + +G+S ++ W APE + G +T+ D W FG
Sbjct 805 ARLGHSPQGSSSLLR---------------------WAAPEVITHG--KYTTSSDVWSFG 841
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833
+ E+ GE P + E + +++ RL
Sbjct 842 ILMWEVMSYGERPYWDMNEQEVLNAIEQEFRL 873
>sp|Q9LN59|WAKLK_ARATH Putative wall-associated receptor kinase-like
11 OS=Arabidopsis thaliana OX=3702 GN=WAKL11 PE=3 SV=2
Length=788
Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 70/260 (27%), Positives = 114/260 (44%), Gaps = 18/260 (7%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
G VAVK K + E+ IL + H H++K GCC + + LV E++P
Sbjct 473 GRTVAVKKSKV-VDEDKLEEFINEVVILSQINHRHVVKLLGCCLET--EVPTLVYEFIPN 529
Query 984 GSLRDYLPRHSIGLAQL----LLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRL 1036
G+L ++ S + L A I ++YLH+ HRD+ + N+LLD
Sbjct 530 GNLFQHIHEESDDYTKTWGMRLRIAVDIAGALSYLHSAASSPIYHRDIKSTNILLDEKYR 589
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
K+ DFG +++V H ++ G V + PE ++ SDV+SFGV L EL+T
Sbjct 590 TKVSDFGTSRSVTIDHTHWTTVISG--TVGYVDPEYYGSSQYTDKSDVYSFGVVLVELIT 647
Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE----VYHLMKNCW 1152
+ + E+ G+A ++ E + R D C E V +L + C
Sbjct 648 G-EKPVITVSNSQEIRGLADHFRVAMKENRFFEIMDARIR-DGCKPEQVMAVANLARRCL 705
Query 1153 ETEASFRPTFENLIPILKTV 1172
++ RP + L+ +
Sbjct 706 NSKGKKRPCMRKVFTDLEKI 725
Score = 62.8 bits (151), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 76/328 (23%), Positives = 128/328 (39%), Gaps = 74/328 (23%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LGQG + VY+G L + ++ K+ DED L
Sbjct 457 LGQGGQGTVYKGMLVDGRTVAVKKSKVVDEDKLEE------------------------- 491
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM-- 712
F ++SQ++H H+ + G C+ +V E++ +G L + E W M
Sbjct 492 FINEVVILSQINHRHVVKLLGCCLETEVPTLVYEFIPNGNLFQHIHEESDDYTKTWGMRL 551
Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+A +A ALSYL + + H ++ NILL K+SD G SR
Sbjct 552 RIAVDIAGALSYLHSAASSPIYHRDIKSTNILLDE-------KYRTKVSDFGT-----SR 599
Query 770 EERVERIPW----------LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
++ W + PE G++ + D + FG L+E+ GE P+ + S
Sbjct 600 SVTIDHTHWTTVISGTVGYVDPEYY--GSSQYTDKSDVYSFGVVLVEL-ITGEKPVITVS 656
Query 820 PSEK-----EHF--YQRQHRLPE-------PSCP-----QLATLTSQCLTYEPTQRPSFR 860
S++ +HF +++R E C +A L +CL + +RP R
Sbjct 657 NSQEIRGLADHFRVAMKENRFFEIMDARIRDGCKPEQVMAVANLARRCLNSKGKKRPCMR 716
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASD 888
+ DL ++ ++ + D A D
Sbjct 717 KVFTDLEKILASQEDSLVNIENDDGADD 744
>sp|Q15349|KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 OS=Homo
sapiens OX=9606 GN=RPS6KA2 PE=1 SV=2
Length=733
Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 62/212 (29%), Positives = 110/212 (52%), Gaps = 13/212 (6%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWK 945
+DP+ F + ++ LG+G +GKV L +D G++ A+K LK A + R K
Sbjct 54 ADPSQF-----ELLKVLGQGSYGKVFLVRKVKGSDA-GQLYAMKVLKKATLKVRDRVRSK 107
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ-LLLFA 1004
E DIL + H I+K + +G+ L L+++++ G L L + + + + +
Sbjct 108 MERDILAEVNHPFIVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYL 165
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
++ + +LH+ I+RDL N+LLD + +KI DFGL+K E ++ +
Sbjct 166 AELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSK---EAIDHDKRAYSFCGT 222
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+ + APE + ++D WSFGV ++E+LT
Sbjct 223 IEYMAPEVVNRRGHTQSADWWSFGVLMFEMLT 254
Score = 62.8 bits (151), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 64/232 (28%), Positives = 100/232 (43%), Gaps = 44/232 (19%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL-RTLYHEHII 960
D+G G + C + T AVK + + + +EI+IL R H +II
Sbjct 420 DIGVGSYS----VCKRCVHKATDTEYAVKIID-----KSKRDPSEEIEILLRYGQHPNII 470
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ--------ICEGMA 1012
K +D K + LVME + G L D + R F+++ I + M
Sbjct 471 TLKDVYDDG--KFVYLVMELMRGGELLDRILRQR-------YFSEREASDVLCTITKTMD 521
Query 1013 YLHAQHYIHRDLAARNVLLDND----RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-- 1066
YLH+Q +HRDL N+L ++ +++ DFG AK + G+ +P +
Sbjct 522 YLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLM------TPCYTA 575
Query 1067 -WYAPECLKEYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELIG 1113
+ APE LK + A D+WS G+ LY +L + P + L IG
Sbjct 576 NFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIG 627
>sp|P06244|KAPA_YEAST cAMP-dependent protein kinase type 1 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=TPK1 PE=1 SV=3
Length=397
Score = 79.7 bits (195), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 62/200 (31%), Positives = 99/200 (50%), Gaps = 17/200 (9%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTLYHE 957
+R LG G FG+V L + G A+K LK + + + E +L + H
Sbjct 90 LRTLGTGSFGRVHLI----RSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHP 145
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL--LFAQQICEGMAYLH 1015
II+ G +D + + ++M+Y+ G L L R S + +A ++C + YLH
Sbjct 146 FIIRMWGTFQDA--QQIFMIMDYIEGGELFSLL-RKSQRFPNPVAKFYAAEVCLALEYLH 202
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
++ I+RDL N+LLD + +KI DFG AK VP+ Y + D + APE +
Sbjct 203 SKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVT--YTLCGTPD----YIAPEVVST 256
Query 1076 YKFYYASDVWSFGVTLYELL 1095
+ + D WSFG+ +YE+L
Sbjct 257 KPYNKSIDWWSFGILIYEML 276
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 45/197 (23%), Positives = 84/197 (43%), Gaps = 11/197 (6%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
++S V+H + + G + M+ +Y+E G L LR+ + P A ++
Sbjct 138 MLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQ-RFPNPVAKFYAAEVCL 196
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-WL 779
AL YL +K++++ ++ NILL + G IK++D G + P ++
Sbjct 197 ALEYLHSKDIIYRDLKPENILLDKNG-------HIKITDFGFAKYVPDVTYTLCGTPDYI 249
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP 839
APE + + ++D W FG + E+ S + E + R P
Sbjct 250 APEVV--STKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNE 307
Query 840 QLATLTSQCLTYEPTQR 856
+ L S+ +T + +QR
Sbjct 308 DVKDLLSRLITRDLSQR 324
>sp|Q99JP0|M4K3_MOUSE Mitogen-activated protein kinase kinase
kinase kinase 3 OS=Mus musculus OX=10090 GN=Map4k3 PE=1 SV=4
Length=894
Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 56/199 (28%), Positives = 102/199 (51%), Gaps = 14/199 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I+ +G G +G V Y N TGE+ A+K +K + G + + +QEI +++ H +I
Sbjct 19 IQRIGSGTYGDV----YKARNVNTGELAAIKVIKLEPG-EDFAVVQQEIIMMKDCKHPNI 73
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ Y G + + L + ME+ GSL+D Y + Q+ +++ +G+ YLH++
Sbjct 74 VAYFGSYLRRDK--LWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKG 131
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL---KE 1075
+HRD+ N+LL ++ VK+ DFG++ + R+ +W APE ++
Sbjct 132 KMHRDIKGANILLTDNGHVKLADFGVSAQITAT---IAKRKSFIGTPYWMAPEVAAVERK 188
Query 1076 YKFYYASDVWSFGVTLYEL 1094
+ D+W+ G+T EL
Sbjct 189 GGYNQLCDLWAVGITAIEL 207
Score = 40.8 bits (94), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 67/304 (22%), Positives = 115/304 (38%), Gaps = 52/304 (17%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
R Q++ + +G GT +VY+ R + G+ + +
Sbjct 10 RNPQEDFELIQRIGSGTYGDVYKAR----------------------NVNTGELAAIKVI 47
Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRR 701
L+P D A+ E +M H ++ G +R + + E+ G L D++
Sbjct 48 KLEPGE-DFAVVQQEII-MMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIY--H 103
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
G + V+++ L YL +K +H ++ G NILL G +KL+D G
Sbjct 104 VTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNG-------HVKLADFG 156
Query 762 VG---LGALSREERVERIP-WLAPECLP----GGANSLSTAMDKWGFGATLLEIC----- 808
V +++ + P W+APE GG N L D W G T +E+
Sbjct 157 VSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLC---DLWAVGITAIELAELQPP 213
Query 809 -FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
FD P+++ K +F + + LT P +RP+ +L+
Sbjct 214 MFDLH-PMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKKRPNAEKLLQHPF 272
Query 868 RLQP 871
QP
Sbjct 273 VTQP 276
>sp|O04534|LRK51_ARATH Putative L-type lectin-domain containing
receptor kinase V.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK51
PE=3 SV=1
Length=666
Score = 80.9 bits (198), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 65/207 (31%), Positives = 99/207 (48%), Gaps = 21/207 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---EIDILRT 953
K LG+G FGKV Y T + +AVK + D R G ++ EI +
Sbjct 344 FKDTEVLGKGGFGKV----YKGTLPVSNVEIAVKMVSHDS----RQGMREFIAEIATIGR 395
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEG 1010
L H ++++ +G C +GE L LV + + GSL +L G +Q + + G
Sbjct 396 LRHPNLVRLQGYCRHKGE--LYLVYDCMAKGSLDKFLYHQQTGNLDWSQRFKIIKDVASG 453
Query 1011 MAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH Q IHRD+ N+LLD + K+GDFGLAK G + G + +
Sbjct 454 LYYLHQQWVQVIIHRDIKPANILLDANMNAKLGDFGLAKLCDHGTDPQTSHVAG--TLGY 511
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYEL 1094
+PE + K SDV++FG+ + E+
Sbjct 512 ISPELSRTGKASTRSDVFAFGIVMLEI 538
>sp|Q9SYS7|CRK39_ARATH Putative cysteine-rich receptor-like protein
kinase 39 OS=Arabidopsis thaliana OX=3702 GN=CRK39 PE=3
SV=1
Length=659
Score = 80.9 bits (198), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 66/201 (33%), Positives = 97/201 (48%), Gaps = 16/201 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V Y N G+ VAVK L G Q +K E+ +L L H +++K
Sbjct 359 LGQGGFGTV--YKGTLLN---GQEVAVKRLTKGSG-QGDIEFKNEVSLLTRLQHRNLVKL 412
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017
G C ++G++ + LV E+VP SL ++ R + + I G+ YLH
Sbjct 413 LGFC-NEGDEQI-LVYEFVPNSSLDHFIFDDEKRSLLTWEMRYRIIEGIARGLLYLHEDS 470
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
IHRDL A N+LLD + K+ DFG A+ + + + APE L
Sbjct 471 QLKIIHRDLKASNILLDAEMNPKVADFGTARLFDSDETRAETKRIAGTRGY-MAPEYLNH 529
Query 1076 YKFYYASDVWSFGVTLYELLT 1096
+ SDV+SFGV L E+++
Sbjct 530 GQISAKSDVYSFGVMLLEMIS 550
Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 78/299 (26%), Positives = 124/299 (41%), Gaps = 57/299 (19%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
E + + LGQG VY+G L GQE V +K L
Sbjct 352 EFSSENTLGQGGFGTVYKGTLL-----------------------NGQE--VAVKRLTKG 386
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
+ F SL++++ H +L + G C G E I+V E+V + LD ++ +
Sbjct 387 SGQGDIEFKNEVSLLTRLQHRNLVKLLGFCNEGDEQILVYEFVPNSSLDHFIFDDEKRSL 446
Query 708 MAWKM--VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ W+M + + +A L YL + ++H ++ NILL AE +P K++D G
Sbjct 447 LTWEMRYRIIEGIARGLLYLHEDSQLKIIHRDLKASNILLD----AE-MNP--KVADFGT 499
Query 763 GLGALSREERVE--RIP----WLAPECLPGGANSLSTAMDKWGFGATLLEIC-------F 809
S E R E RI ++APE L G +S D + FG LLE+ F
Sbjct 500 ARLFDSDETRAETKRIAGTRGYMAPEYLNHG--QISAKSDVYSFGVMLLEMISGERNNSF 557
Query 810 DGE---APLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTIL 863
+GE A R K + +P +L + C+ PT+RP+ +++
Sbjct 558 EGEGLAAFAWKRWVEGKPEIIIDPFLIEKPRNEIIKLIQIGLLCVQENPTKRPTMSSVI 616
>sp|Q6BNF3|STE20_DEBHA Serine/threonine-protein kinase STE20 OS=Debaryomyces
hansenii (strain ATCC 36239 / CBS 767 / BCRC
21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=STE20
PE=3 SV=2
Length=1079
Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 56/208 (27%), Positives = 104/208 (50%), Gaps = 13/208 (6%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP +K +K +G+G G V Y N + + VA+K + + P+ + E
Sbjct 796 DPNELYKDLMK----IGQGASGGV--YIAHDVNHRS-QTVAIKQMNLEQQPK-KELIINE 847
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +++ HE+I+ + +G+ L +VMEY+ GSL + + + Q+ ++
Sbjct 848 ILVMKGSKHENIVNFIDSYLLRGD--LWVVMEYMEGGSLTEIVTHSVMTEGQIGAVCRET 905
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+G+ +LH++ IHRD+ + N+LL+ D +K+ DFG + +E R +W
Sbjct 906 LKGLRFLHSKGVIHRDIKSDNILLNIDGNIKMTDFGFCAQI---NEINLKRTTMVGTPYW 962
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095
APE + ++ DVWS G+ + E++
Sbjct 963 MAPEVVSRKEYGPKVDVWSLGIMIIEMI 990
Score = 37.7 bits (86), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 22/167 (13%)
Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQ 717
+M H ++ F+ +RG + +V EY+E G L + H M + V ++
Sbjct 850 VMKGSKHENIVNFIDSYLLRG-DLWVVMEYMEGGSLTEIVT----HSVMTEGQIGAVCRE 904
Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERV 773
L +L +K ++H ++ NILL G IK++D G + L R V
Sbjct 905 TLKGLRFLHSKGVIHRDIKSDNILLNIDG-------NIKMTDFGFCAQINEINLKRTTMV 957
Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
W+APE + +D W G ++E+ +GE P + +P
Sbjct 958 GTPYWMAPEVV--SRKEYGPKVDVWSLGIMIIEM-IEGEPPYLNETP 1001
>sp|Q75H77|SAPKA_ORYSJ Serine/threonine-protein kinase SAPK10
OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK10 PE=1 SV=1
Length=362
Score = 79.3 bits (194), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 79/239 (33%), Positives = 115/239 (48%), Gaps = 27/239 (11%)
Query 885 PASDPTVFHK--RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
P D + H RY + +RD+G G+FG L + G++VAVK ++ G +
Sbjct 10 PGMDMPIMHDGDRY-ELVRDIGSGNFGVARLM----RSRADGQLVAVKYIER--GDKIDE 62
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQ 999
++EI R+L H +II++K L +VMEY G L + + R S A+
Sbjct 63 NVQREIINHRSLRHPNIIRFKEVI--LTPTHLAIVMEYASGGELFERICNAGRFSEDEAR 120
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL--VKIGDFGLAKAVPEGHEYYRV 1057
F QQ+ G++Y H+ HRDL N LLD +KI DFG +K+ + +
Sbjct 121 F--FFQQLISGVSYCHSMQVCHRDLKLENTLLDGSTAPRLKICDFGYSKS---SVLHSQP 175
Query 1058 REDGDSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLELI 1112
+ +P + APE L KEY A DVWS GVTLY +L + P P F + I
Sbjct 176 KSTVGTPA-YIAPEVLLKKEYDGKIA-DVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 232
Score = 34.3 bits (77), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 46/191 (24%), Positives = 75/191 (39%), Gaps = 37/191 (19%)
Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER 775
QQL S +SY + VC R++ L L T+P +K+ D G ++ +
Sbjct 124 QQLISGVSYCHSM-----QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST 178
Query 776 I---PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832
+ ++APE L A D W G TL + G P + P E ++F + R
Sbjct 179 VGTPAYIAPEVLLKKEYDGKIA-DVWSCGVTLY-VMLVGAYPFE--DPDEPKNFRKTIQR 234
Query 833 L--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
+ + S P ++ +C RDL +A + NP + S P
Sbjct 235 ILGVQYSIPDYVHISPEC---------------RDL-------IARIFVANPATRISIPE 272
Query 891 V-FHKRYLKKI 900
+ H +LK +
Sbjct 273 IRNHPWFLKNL 283
>sp|Q9SA25|WAKLG_ARATH Wall-associated receptor kinase-like 8
OS=Arabidopsis thaliana OX=3702 GN=WAKL8 PE=2 SV=1
Length=720
Score = 80.9 bits (198), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 73/263 (28%), Positives = 123/263 (47%), Gaps = 13/263 (5%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
G +VAVK KA ++ + EI +L + H +++K GCC + + LV E++P
Sbjct 412 GMIVAVKKSKA-LKEENLEEFINEIILLSQINHRNVVKILGCCLET--EVPILVYEFIPN 468
Query 984 GSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQHYI---HRDLAARNVLLDNDRL 1036
+L D+L S + L A ++ + ++YLH+ I HRD+ + N+LLD
Sbjct 469 RNLFDHLHNPSEDFPMSWEVRLCIACEVADALSYLHSAVSIPIYHRDVKSTNILLDEKHR 528
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
K+ DFG++++V + G + + PE L+ F SDV+SFGV L ELLT
Sbjct 529 AKVSDFGISRSVAIDDTHLTTIVQG--TIGYVDPEYLQSNHFTGKSDVYSFGVLLIELLT 586
Query 1097 HCDSSQSPPTKFLELIGIAQGQ-MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155
+ + ++G + M RL E+L+ + + V L + C
Sbjct 587 GEKPVSLLRRQEVRMLGAYFLEAMRNDRLHEILDARIKEECDREEVLAVAKLARRCLSLN 646
Query 1156 ASFRPTFENLIPILKTVHEKYQG 1178
+ RPT ++ L + K +G
Sbjct 647 SEHRPTMRDVFIELDRMQSKRKG 669
Score = 62.0 bits (149), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 74/304 (24%), Positives = 124/304 (41%), Gaps = 63/304 (21%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LGQG + VY+G L ED ++ + + L+ +
Sbjct 396 LGQGGQGTVYKGML---------------EDGMIVAVKKSKALK----------EENLEE 430
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F L+SQ++H ++ + G C+ I+V E++ + L L PM+W ++
Sbjct 431 FINEIILLSQINHRNVVKILGCCLETEVPILVYEFIPNRNLFDHLHNPSEDFPMSWEVRL 490
Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+A ++A ALSYL + + H +V NILL A K+SD G+
Sbjct 491 CIACEVADALSYLHSAVSIPIYHRDVKSTNILLDEKHRA-------KVSDFGISRSVAID 543
Query 770 EERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ + I ++ PE L +N + D + FG L+E+ GE P+ E
Sbjct 544 DTHLTTIVQGTIGYVDPEYLQ--SNHFTGKSDVYSFGVLLIEL-LTGEKPVSLLRRQEVR 600
Query 825 ----HFYQ--RQHRLPE-------PSCPQ-----LATLTSQCLTYEPTQRPSFRTILRDL 866
+F + R RL E C + +A L +CL+ RP+ R + +L
Sbjct 601 MLGAYFLEAMRNDRLHEILDARIKEECDREEVLAVAKLARRCLSLNSEHRPTMRDVFIEL 660
Query 867 TRLQ 870
R+Q
Sbjct 661 DRMQ 664
>sp|Q9Y884|SKH1_SCHPO MAP kinase kinase skh1/pek1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=skh1
PE=3 SV=1
Length=363
Score = 79.0 bits (193), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 59/200 (30%), Positives = 90/200 (45%), Gaps = 14/200 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG G V GT + A+K + A + +E+ I R+ +I
Sbjct 82 MNSLGEGVSGSVR----KCRIRGTQMIFAMKTVLAAPNTALQKQLLRELKINRSCTSPYI 137
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQICEGMAYL 1014
+KY G C + E L + MEY GSL R G L A + G++YL
Sbjct 138 VKYYGACYNNAECQLNIAMEYCGAGSLDAIYKRVRSQGGRTGERPLGKIAFGVLSGLSYL 197
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H + IHRD+ N+LL + VK+ DFG++ G + ++ APE +
Sbjct 198 HDRKIIHRDIKPSNILLTSKGQVKLCDFGVS-----GELVNSLAGTFTGTSYYMAPERIS 252
Query 1075 EYKFYYASDVWSFGVTLYEL 1094
+ +SD+WS G+TL E+
Sbjct 253 GGSYTISSDIWSLGLTLMEV 272
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 51/193 (26%), Positives = 83/193 (43%), Gaps = 27/193 (14%)
Query 631 RDRGQELRVVLK-VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE---NIMV 686
R RG ++ +K VL + + + + ++ +G C E NI +
Sbjct 97 RIRGTQMIFAMKTVLAAPNTALQKQLLRELKINRSCTSPYIVKYYGACYNNAECQLNIAM 156
Query 687 TEYVEHGPLDVWLRRER------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNI 740
EY G LD +R R G P+ +A + S LSYL ++ ++H ++ NI
Sbjct 157 -EYCGAGSLDAIYKRVRSQGGRTGERPLG---KIAFGVLSGLSYLHDRKIIHRDIKPSNI 212
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDK 797
LL G +KL D GV G L ++APE + GG+ ++S+ D
Sbjct 213 LLTSKGQ-------VKLCDFGVS-GELVNSLAGTFTGTSYYMAPERISGGSYTISS--DI 262
Query 798 WGFGATLLEICFD 810
W G TL+E+ +
Sbjct 263 WSLGLTLMEVALN 275
>sp|C0LGG7|Y1534_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g53420 OS=Arabidopsis thaliana OX=3702
GN=At1g53420 PE=2 SV=2
Length=953
Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 85/288 (30%), Positives = 133/288 (46%), Gaps = 41/288 (14%)
Query 903 LGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+GEG FG V L+ DGT ++AVK L +R + EI ++ L+H ++
Sbjct 630 IGEGGFGPVYKGKLF------DGT--IIAVKQLSTGSKQGNRE-FLNEIGMISALHHPNL 680
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLL---FAQQIC----EG 1010
+K GCC + G+ L LV E+V SL L P+ + QL L ++IC G
Sbjct 681 VKLYGCCVEGGQ--LLLVYEFVENNSLARALFGPQET----QLRLDWPTRRKICIGVARG 734
Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+AYLH + +HRD+ A NVLLD KI DFGLAK E + R G F
Sbjct 735 LAYLHEESRLKIVHRDIKATNVLLDKQLNPKISDFGLAKLDEEDSTHISTRIAG---TFG 791
Query 1068 Y-APECLKEYKFYYASDVWSFGVTLYELL----THCDSSQSPPTKFLELIGIAQGQMTVL 1122
Y APE +DV+SFG+ E++ + S++ ++ + + + + +L
Sbjct 792 YMAPEYAMRGHLTDKADVYSFGIVALEIVHGRSNKIERSKNNTFYLIDWVEVLREKNNLL 851
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
L + G R + +M C +E RP+ ++ +L+
Sbjct 852 ELVD-PRLGSEYNREEAMTMIQIAIM--CTSSEPCERPSMSEVVKMLE 896
Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 62/250 (25%), Positives = 107/250 (43%), Gaps = 57/250 (23%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH--------GPLDVWLRRERGHV 706
F ++S + H +L ++G CV G + ++V E+VE+ GP + LR +
Sbjct 665 FLNEIGMISALHHPNLVKLYGCCVEGGQLLLVYEFVENNSLARALFGPQETQLRLDW--- 721
Query 707 PMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
P K+ + +A L+YL ++ +VH ++ N+LL + +P K+SD G
Sbjct 722 PTRRKICIG--VARGLAYLHEESRLKIVHRDIKATNVLLDK-----QLNP--KISD--FG 770
Query 764 LGALSREERV---ERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
L L E+ RI ++APE G L+ D + FG LEI ++
Sbjct 771 LAKLDEEDSTHISTRIAGTFGYMAPEYAMRG--HLTDKADVYSFGIVALEIVHGRSNKIE 828
Query 817 SRSPSEKEHFY--------QRQHRLPEPSCPQLAT------------LTSQCLTYEPTQR 856
S+ FY + ++ L E P+L + + C + EP +R
Sbjct 829 R---SKNNTFYLIDWVEVLREKNNLLELVDPRLGSEYNREEAMTMIQIAIMCTSSEPCER 885
Query 857 PSFRTILRDL 866
PS +++ L
Sbjct 886 PSMSEVVKML 895
>sp|A0A1D6E0S8|WAK17_MAIZE Wall-associated receptor kinase 17
OS=Zea mays OX=4577 GN=WAK17 PE=1 SV=1
Length=856
Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 11/160 (7%)
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQ 999
+ EI IL + H +++K GCC + + LV E++ G+L ++ + +
Sbjct 568 FVNEIAILSQIDHPNVVKLLGCCLET--QVPLLVYEFISNGTLFQHIHNRNATRPLTWED 625
Query 1000 LLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
L A + + +AYLH+ IHRD+ + N+LLD + + KI DFG +++VP +
Sbjct 626 CLRIAAETADALAYLHSASSIPIIHRDIKSSNILLDGNFVAKIADFGASRSVPFDQTHIT 685
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
G + + PE + + SDV+SFGV L ELLT
Sbjct 686 TLIQGT--IGYLDPEYFQSSQLTEKSDVYSFGVVLAELLT 723
Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 62/302 (21%), Positives = 122/302 (40%), Gaps = 41/302 (14%)
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
KV D S + F +++SQ+ H ++ + G C+ ++V E++ +G L +
Sbjct 558 KVFDESQVE---QFVNEIAILSQIDHPNVVKLLGCCLETQVPLLVYEFISNGTLFQHIHN 614
Query 702 ERGHVPMAWK--MVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIK 756
P+ W+ + +A + A AL+YL + + ++H ++ NILL +A K
Sbjct 615 RNATRPLTWEDCLRIAAETADALAYLHSASSIPIIHRDIKSSNILLDGNFVA-------K 667
Query 757 LSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G + + I +L PE ++ L+ D + FG L E+
Sbjct 668 IADFGASRSVPFDQTHITTLIQGTIGYLDPEYFQ--SSQLTEKSDVYSFGVVLAEL-LTR 724
Query 812 EAPLQSRSPSEKEHFYQ------RQHRL------------PEPSCPQLATLTSQCLTYEP 853
+ P+ + P + + + RL E C +A L+ +CL +
Sbjct 725 QKPISAARPEDSCNLAMHLVVLFNKGRLLQEIEPHILAEAGEDQCYAVAELSVRCLNVKG 784
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
+RP+ + L L+ D D + + +++L + R + +VS
Sbjct 785 EERPAMVVVASVLQELRRSFTIDQAVGIKDESIQENSEQEEKHLHESRSIPSLQSSEVST 844
Query 914 YC 915
C
Sbjct 845 QC 846
>sp|O65472|CRK12_ARATH Putative cysteine-rich receptor-like protein
kinase 12 OS=Arabidopsis thaliana OX=3702 GN=CRK12 PE=3
SV=3
Length=659
Score = 80.9 bits (198), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 72/206 (35%), Positives = 97/206 (47%), Gaps = 20/206 (10%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
K LG+G FG+V Y T G VAVK L + Q +K E+ ++ L H +
Sbjct 338 KTNKLGQGGFGEV----YKGTLVN-GTEVAVKRL-SKTSEQGAQEFKNEVVLVAKLQHRN 391
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAY 1013
++K G C + EK L V E+VP SL DY QL I G+ Y
Sbjct 392 LVKLLGYCLEPEEKIL--VYEFVPNKSL-DYFLFDPTKQGQLDWTKRYNIIGGITRGILY 448
Query 1014 LHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA- 1069
LH IHRDL A N+LLD D + KI DFG+A+ G + + F Y
Sbjct 449 LHQDSRLTIIHRDLKASNILLDADMIPKIADFGMARI--SGIDQSVANTKRIAGTFGYMP 506
Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095
PE + +F SDV+SFGV + E++
Sbjct 507 PEYVIHGQFSMKSDVYSFGVLILEII 532
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 68/321 (21%), Positives = 124/321 (39%), Gaps = 53/321 (17%)
Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
TL+ QL F ++ + + + LGQG VY+G L V G+
Sbjct 318 TLHFQQLDFKTIEVATENFAKTNKLGQGGFGEVYKGTL-VNGT----------------- 359
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
V +K L + A F L++++ H +L + G C+ E I+V E+V
Sbjct 360 -------EVAVKRLSKTSEQGAQEFKNEVVLVAKLQHRNLVKLLGYCLEPEEKILVYEFV 412
Query 691 EHGPLDVWLR--RERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745
+ LD +L ++G + + + + + YL + ++H ++ NILL
Sbjct 413 PNKSLDYFLFDPTKQGQLDWTKRYNIIGGITRGILYLHQDSRLTIIHRDLKASNILLDA- 471
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ + F G+ + + ++ PE + G S+ + D + FG +L
Sbjct 472 DMIPKIADFGMARISGIDQSVANTKRIAGTFGYMPPEYVIHGQFSMKS--DVYSFGVLIL 529
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP-QLATLTSQ----------------- 847
EI + ++ ++ E+ RL P +L LT
Sbjct 530 EIICGKKNRSFYQADTKAENLVTYVWRLWTNGSPLELVDLTISENCQTEEVIRCIHIALL 589
Query 848 CLTYEPTQRPSFRTILRDLTR 868
C+ +P RP+ TI+ LT
Sbjct 590 CVQEDPKDRPNLSTIMMMLTN 610
>sp|Q8IVH8|M4K3_HUMAN Mitogen-activated protein kinase kinase
kinase kinase 3 OS=Homo sapiens OX=9606 GN=MAP4K3 PE=1 SV=1
Length=894
Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 56/199 (28%), Positives = 102/199 (51%), Gaps = 14/199 (7%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I+ +G G +G V Y N TGE+ A+K +K + G + + +QEI +++ H +I
Sbjct 19 IQRIGSGTYGDV----YKARNVNTGELAAIKVIKLEPG-EDFAVVQQEIIMMKDCKHPNI 73
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ Y G + + L + ME+ GSL+D Y + Q+ +++ +G+ YLH++
Sbjct 74 VAYFGSYLRRDK--LWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKG 131
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL---KE 1075
+HRD+ N+LL ++ VK+ DFG++ + R+ +W APE ++
Sbjct 132 KMHRDIKGANILLTDNGHVKLADFGVSAQITAT---IAKRKSFIGTPYWMAPEVAAVERK 188
Query 1076 YKFYYASDVWSFGVTLYEL 1094
+ D+W+ G+T EL
Sbjct 189 GGYNQLCDLWAVGITAIEL 207
Score = 41.2 bits (95), Expect = 0.069, Method: Compositional matrix adjust.
Identities = 73/322 (23%), Positives = 122/322 (38%), Gaps = 59/322 (18%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
R Q++ + +G GT +VY+ R + G+ + +
Sbjct 10 RNPQEDFELIQRIGSGTYGDVYKAR----------------------NVNTGELAAIKVI 47
Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRR 701
L+P D A+ E +M H ++ G +R + + E+ G L D++
Sbjct 48 KLEPGE-DFAVVQQEII-MMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIY--H 103
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
G + V+++ L YL +K +H ++ G NILL G +KL+D G
Sbjct 104 VTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNG-------HVKLADFG 156
Query 762 VG---LGALSREERVERIP-WLAPECLP----GGANSLSTAMDKWGFGATLLEIC----- 808
V +++ + P W+APE GG N L D W G T +E+
Sbjct 157 VSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLC---DLWAVGITAIELAELQPP 213
Query 809 -FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL---- 863
FD P+++ K +F + + LT P +RP+ +L
Sbjct 214 MFDLH-PMRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPF 272
Query 864 --RDLTRLQPHNLADVLTVNPD 883
+ LTR L D + NPD
Sbjct 273 VTQHLTRSLAIELLDKVN-NPD 293
>sp|Q8RY67|WAKLO_ARATH Wall-associated receptor kinase-like 14
OS=Arabidopsis thaliana OX=3702 GN=WAKL14 PE=2 SV=2
Length=708
Score = 80.9 bits (198), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 67/207 (32%), Positives = 101/207 (49%), Gaps = 26/207 (13%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK-----QEIDILRTLY 955
+ LG G +G V Y ND E VA+K L+ HR EI +L ++
Sbjct 352 QKLGIGAYGTV--YRGKLQND---EWVAIKRLR------HRDSESLDQVMNEIKLLSSVS 400
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGL--AQLLLFAQQICEGMA 1012
H ++++ GCC +QG+ LV EY+P G+L ++L R GL L A Q + +A
Sbjct 401 HPNLVRLLGCCIEQGDP--VLVYEYMPNGTLSEHLQRDRGSGLPWTLRLTVATQTAKAIA 458
Query 1013 YLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH+ HRD+ + N+LLD D K+ DFGL++ + G +
Sbjct 459 YLHSSMNPPIYHRDIKSTNILLDYDFNSKVADFGLSRLGMTESSHISTAPQGTPG--YLD 516
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096
P+ + + SDV+SFGV L E++T
Sbjct 517 PQYHQCFHLSDKSDVYSFGVVLAEIIT 543
Score = 55.1 bits (131), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 22/158 (14%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLA 719
L+S VSH +L + G C+ + ++V EY+ +G L L+R+RG +P ++ VA Q A
Sbjct 395 LLSSVSHPNLVRLLGCCIEQGDPVLVYEYMPNGTLSEHLQRDRGSGLPWTLRLTVATQTA 454
Query 720 SALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI 776
A++YL N + H ++ NILL + K++D G+ ++ +
Sbjct 455 KAIAYLHSSMNPPIYHRDIKSTNILLDYDFNS-------KVADFGLSRLGMTESSHIST- 506
Query 777 PWLAPECLPGGAN-------SLSTAMDKWGFGATLLEI 807
AP+ PG + LS D + FG L EI
Sbjct 507 ---APQGTPGYLDPQYHQCFHLSDKSDVYSFGVVLAEI 541
>sp|O15111|IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase
subunit alpha OS=Homo sapiens OX=9606 GN=CHUK PE=1 SV=2
Length=745
Score = 80.9 bits (198), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 62/206 (30%), Positives = 96/206 (47%), Gaps = 24/206 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V LY + + +A+K+ + + ++R W EI I++ L H +++K
Sbjct 21 LGTGGFGNVCLYQHRELDLK----IAIKSCRLELSTKNRERWCHEIQIMKKLNHANVVK- 75
Query 963 KGCCEDQGEKSLQ------LVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMA 1012
C+ E ++ L MEY G LR L P + GL +Q+L I G+
Sbjct 76 --ACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIR 133
Query 1013 YLHAQHYIHRDLAARNVLLDN---DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH IHRDL N++L + + KI D G AK V +G + + + A
Sbjct 134 YLHENKIIHRDLKPENIVLQDVGGKIIHKIIDLGYAKDVDQG----SLCTSFVGTLQYLA 189
Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095
PE + + D WSFG ++E +
Sbjct 190 PELFENKPYTATVDYWSFGTMVFECI 215
>sp|Q8CFH6|SIK2_MOUSE Serine/threonine-protein kinase SIK2 OS=Mus
musculus OX=10090 GN=Sik2 PE=1 SV=1
Length=931
Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 63/196 (32%), Positives = 91/196 (46%), Gaps = 13/196 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG+G+F V L + T VA+K + K+ + +E+ I++ L H HIIK
Sbjct 26 LGKGNFAVVKLGRHRTTKTE----VAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIK 81
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020
E + L LV EY G + DYL H + ++ QI + Y H + +
Sbjct 82 LYQVMETKS--MLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKVV 139
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDL A N+LLDN+ +KI DFG G G P + APE + ++
Sbjct 140 HRDLKAENLLLDNNMNIKIADFGFGNFFKTGE--LLATWCGSPP--YAAPEVFEGQQYEG 195
Query 1081 AS-DVWSFGVTLYELL 1095
D+WS GV LY L+
Sbjct 196 PQLDIWSMGVVLYVLV 211
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 48/192 (25%), Positives = 79/192 (41%), Gaps = 19/192 (10%)
Query 630 GRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
GR R + V +K++D S D Y +M + H H+ ++ V +VT
Sbjct 37 GRHRTTKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVT 96
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
EY ++G + +L G + + Q+ SA+ Y + +VH ++ N+LL
Sbjct 97 EYAKNGEIFDYLAN-HGRLNESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLL----- 150
Query 748 AEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+ IK++D G G + E P+ APE G +D W G L
Sbjct 151 --DNNMNIKIADFGFGNFFKTGELLATWCGSPPYAAPEVFEGQQYE-GPQLDIWSMGVVL 207
Query 805 -LEIC----FDG 811
+ +C FDG
Sbjct 208 YVLVCGALPFDG 219
>sp|Q8GYQ5|MPK12_ARATH Mitogen-activated protein kinase 12 OS=Arabidopsis
thaliana OX=3702 GN=MPK12 PE=1 SV=1
Length=372
Score = 79.0 bits (193), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 65/212 (31%), Positives = 97/212 (46%), Gaps = 21/212 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILR 952
++Y+ IR +G G G V N TGE VA+K + A +EI +LR
Sbjct 38 RKYVPPIRPIGRGACGIVCA----AVNSVTGEKVAIKKIGNAFDNIIDAKRTLREIKLLR 93
Query 953 TLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICE 1009
+ HE++I K + + +V E + R ++ Q Q+
Sbjct 94 HMDHENVITIKDIVRPPQRDIFNDVYIVYELMDTDLQRILRSNQTLTSDQCRFLVYQLLR 153
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH---EYYRVREDGDSPVF 1066
G+ Y+H+ + +HRDL NVLL++ +KIGDFGLA+ + EY R
Sbjct 154 GLKYVHSANILHRDLRPSNVLLNSKNELKIGDFGLARTTSDTDFMTEYVVTR-------- 205
Query 1067 WY-APECLKEYKFYYAS-DVWSFGVTLYELLT 1096
WY APE L Y A+ D+WS G L E++T
Sbjct 206 WYRAPELLLNCSEYTAAIDIWSVGCILGEIMT 237
>sp|Q6C3D7|STE20_YARLI Serine/threonine-protein kinase STE20 OS=Yarrowia
lipolytica (strain CLIB 122 / E 150) OX=284591 GN=STE20
PE=3 SV=1
Length=1125
Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 56/208 (27%), Positives = 103/208 (50%), Gaps = 14/208 (7%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DPT ++ +K +G+G G V Y+ G+ VA+K + + P+ + E
Sbjct 839 DPTKLYRNLVK----IGQGASGGV-FTAYE---VGSNLSVAIKQMNLEHQPK-KELIINE 889
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +++ H++I+ + G+ L +VMEY+ GSL D + + + +Q+ ++
Sbjct 890 ILVMKDSKHKNIVNFIDSYLHGGD--LWVVMEYMEGGSLTDVVTYNMMTESQIGAVCRET 947
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
G+ +LH++ IHRD+ + NVLL +K+ DFG + E + R G +W
Sbjct 948 LLGLQHLHSKGVIHRDIKSDNVLLSMRGEIKLTDFGFCAQINESN-LKRTTMVGTP--YW 1004
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095
APE + ++ D+WS G+ E++
Sbjct 1005 MAPEVVSRKEYGSKVDIWSLGIMSIEMI 1032
Score = 44.7 bits (104), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 47/199 (24%), Positives = 80/199 (40%), Gaps = 32/199 (16%)
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
G L V +K ++ H +M H ++ + G + +V EY+E G
Sbjct 865 GSNLSVAIKQMNLEHQPKKELIINEILVMKDSKHKNIVNFIDSYLHGGDLWVVMEYMEGG 924
Query 694 PL-DVWLRRERGHVPMAWKMVVAQQLAS-------ALSYLENKNLVHGNVCGRNILLARL 745
L DV + + M+ Q+ + L +L +K ++H ++ N+LL+
Sbjct 925 SLTDV----------VTYNMMTESQIGAVCRETLLGLQHLHSKGVIHRDIKSDNVLLSMR 974
Query 746 GLAEGTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
G IKL+D G + L R V W+APE + + +D W G
Sbjct 975 G-------EIKLTDFGFCAQINESNLKRTTMVGTPYWMAPEVV--SRKEYGSKVDIWSLG 1025
Query 802 ATLLEICFDGEAPLQSRSP 820
+E+ +GE P + SP
Sbjct 1026 IMSIEM-IEGEPPYLNESP 1043
>sp|Q9LDI3|CIPKO_ARATH CBL-interacting serine/threonine-protein
kinase 24 OS=Arabidopsis thaliana OX=3702 GN=CIPK24 PE=1 SV=1
Length=446
Score = 79.7 bits (195), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 60/199 (30%), Positives = 102/199 (51%), Gaps = 13/199 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEH 958
R +GEG F KV N TG+ VA+K + ++R K+EI I++ + H +
Sbjct 15 RTIGEGTFAKVKF----ARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPN 70
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ 1017
I++ + + +V+E+V G L D + + + ++ + QQ+ + +A+ H +
Sbjct 71 IVRLYEVLASPSK--IYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCK 128
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
HRDL N+LLD + +K+ DFGL+ EG E +R +P + APE L
Sbjct 129 GVYHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVEL--LRTTCGTP-NYVAPEVLSGQG 185
Query 1078 FY-YASDVWSFGVTLYELL 1095
+ A+D+WS GV L+ +L
Sbjct 186 YDGSAADIWSCGVILFVIL 204
Score = 37.0 bits (84), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 59/219 (27%), Positives = 93/219 (42%), Gaps = 31/219 (14%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQL 718
S+M V H ++ ++ V + +V E+V G L D + + R + K QQL
Sbjct 61 SIMKIVRHPNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYF--QQL 118
Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI-- 776
A+++ K + H ++ N+LL T+ +K+SD GL AL +E VE +
Sbjct 119 VDAVAHCHCKGVYHRDLKPENLLL-------DTNGNLKVSD--FGLSALP-QEGVELLRT 168
Query 777 -----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
++APE L G S A D W G L + G P S ++ Y R+
Sbjct 169 TCGTPNYVAPEVLSGQGYDGSAA-DIWSCGVILF-VILAGYLPF---SETDLPGLY-RKI 222
Query 832 RLPEPSCP-----QLATLTSQCLTYEPTQRPSFRTILRD 865
E SCP ++ L + L P R + I +D
Sbjct 223 NAAEFSCPPWFSAEVKFLIHRILDPNPKTRIQIQGIKKD 261
>sp|Q21029|NSY1_CAEEL Mitogen-activated protein kinase kinase
kinase nsy-1 OS=Caenorhabditis elegans OX=6239 GN=nsy-1 PE=1
SV=4
Length=1498
Score = 81.3 bits (199), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 75/272 (28%), Positives = 125/272 (46%), Gaps = 29/272 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G +G V Y + T + VK ++ + + +EI + TL H +I++Y
Sbjct 670 LGKGTYGTV----YAARDMDTQRQIVVKEIEVKYDEEVQP-LMEEISLHSTLCHANIVQY 724
Query 963 KGC---CEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQ 1017
GC +D + ME+VP GSL L + + + +QI EG+ YLH
Sbjct 725 LGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKYLHEL 784
Query 1018 HYIHRDLAARNVLLDN-DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRD+ NVL++ + KI DFG K + + V E + + APE +
Sbjct 785 KIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNP---VTETFTGTLQYMAPEVIDHG 841
Query 1077 KFYYA--SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ Y +D+WSFG T+ E+ T PP F+E+ Q + R+
Sbjct 842 QRGYGAPADIWSFGCTMVEMAT-----GRPP--FVEM---QNPQAAMFRVGMF---KTHP 888
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
P P + + + +K+C+ EA RP+ ++L+
Sbjct 889 PIPTEITEKCRNFIKSCFLPEACDRPSAKDLL 920
Score = 57.8 bits (138), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 56/250 (22%), Positives = 99/250 (40%), Gaps = 22/250 (9%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN-----I 684
RD + ++V+K ++ + + E SL S + H ++ G + G + +
Sbjct 681 ARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFL 740
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+ E+V G L LR + G + +Q+ L YL +VH ++ G N+L+
Sbjct 741 IFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLV-- 798
Query 745 LGLAEGTSPFIKLSDPGV-----GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
S K+SD G GL ++ E + ++APE + G D W
Sbjct 799 ----NTYSGVCKISDFGTCKRLAGLNPVT-ETFTGTLQYMAPEVIDHGQRGYGAPADIWS 853
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHF----YQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855
FG T++E+ G P + F ++ +P + C E
Sbjct 854 FGCTMVEMA-TGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACD 912
Query 856 RPSFRTILRD 865
RPS + +L+D
Sbjct 913 RPSAKDLLQD 922
>sp|Q54GY6|KXCA_DICDI Kinase and exchange factor for Rac A OS=Dictyostelium
discoideum OX=44689 GN=kxcA PE=3 SV=1
Length=1311
Score = 81.3 bits (199), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 77/316 (24%), Positives = 138/316 (44%), Gaps = 69/316 (22%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G+FG V Y G VA+K + + P + ++E+ LR + H ++ +
Sbjct 24 IGKGNFGCVYRGNY------LGVEVAIKQIPSFDDPDYCKYTEREVKALRYIRHPFVVHF 77
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
G C + E L+ E++ LR YL P+ L+++ + A + + +LH+++
Sbjct 78 FGAC--KHESGFYLITEFIEGLDLRRYLKSVPKPPKWLSRVNI-ALGVAKTFLFLHSKNL 134
Query 1020 IHRDLAARNVLLDNDR-LVKIGDFGLAKAVPEGHEY------------------------ 1054
+HRDL ++N+LLD R +K+ DFG A+ G +Y
Sbjct 135 LHRDLKSKNILLDISRNQIKLCDFGFARV---GSQYSNGSDSSSSEDESDSECVNGAAGG 191
Query 1055 ----------------YRVREDG--DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
YR+R +P F PE L + K+ ++ DV+SFG+ EL+T
Sbjct 192 GGDDVYKNNGNGKPANYRLRRMSICGTPSFM-PPEILLQQKYDWSVDVFSFGILCTELIT 250
Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156
+ + +Q + + EL +P P+ CP + Y L C +
Sbjct 251 LKRPGKDYWVR-------SQNNGFDINIEEL---NVNIPSPNDCPIQFYDLALKCCSYKH 300
Query 1157 SFRPTFENLIPILKTV 1172
+ RP F ++ IL+++
Sbjct 301 TNRPMFSTIVTILESI 316
>sp|P34556|CDK1_CAEEL Cyclin-dependent kinase 1 OS=Caenorhabditis
elegans OX=6239 GN=cdk-1 PE=1 SV=1
Length=332
Score = 78.6 bits (192), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 64/218 (29%), Positives = 101/218 (46%), Gaps = 26/218 (12%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEI 948
+V+ K+ +GEG +G V Y N T MVA+K ++ + + S +EI
Sbjct 15 SVYTLNDFTKLEKIGEGTYGVV----YKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREI 70
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR--------DYLPRHSIGLAQL 1000
+L+ L H +++ + E L L+ E++ R +YLP L L
Sbjct 71 SLLKELQHPNVVGLEAVI--MQENRLFLIFEFLSFDLKRYMDQLGKDEYLP-----LETL 123
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+ QI + M + H + IHRDL +N+L+DN+ +K+ DFGLA+A+ Y
Sbjct 124 KSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYT---- 179
Query 1061 GDSPVFWY-APECLKEYKFY-YASDVWSFGVTLYELLT 1096
+ WY APE L + Y D+WS G E+ T
Sbjct 180 HEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEMAT 217
>sp|Q6PDN3|MYLK_MOUSE Myosin light chain kinase, smooth muscle
OS=Mus musculus OX=10090 GN=Mylk PE=1 SV=3
Length=1941
Score = 81.3 bits (199), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 71/256 (28%), Positives = 112/256 (44%), Gaps = 36/256 (14%)
Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911
E + P + D +P +TVN + SD +R LG G FG+V
Sbjct 1448 EKPEEPKDEVEVSDDDEKEPEVDYRTVTVNTEQKVSDVYDIEER-------LGSGKFGQV 1500
Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
+ TG++ A K KA + + +QEI I+ L+H +++ C D E
Sbjct 1501 ----FRLVEKKTGKIWAGKFFKAYSA-KEKDNIRQEISIMNCLHHPKLVQ----CVDAFE 1551
Query 972 KSLQLVM--EYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQHYIHRDLAAR 1027
+ +VM E V G L + + L + + + +QI EG+ Y+H Q +H DL
Sbjct 1552 EKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPE 1611
Query 1028 NVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WYAPECLKEYKFYY 1080
N++ N +K+ DFGLA+ R+ G V + APE + Y
Sbjct 1612 NIMCVNKTGTRIKLIDFGLAR---------RLENAGSLKVLFGTPEFVAPEVINYEPIGY 1662
Query 1081 ASDVWSFGVTLYELLT 1096
A+D+WS GV Y L++
Sbjct 1663 ATDMWSIGVICYILVS 1678
>sp|Q62925|M3K1_RAT Mitogen-activated protein kinase kinase kinase
1 OS=Rattus norvegicus OX=10116 GN=Map3k1 PE=1 SV=1
Length=1493
Score = 81.3 bits (199), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 63/244 (26%), Positives = 118/244 (48%), Gaps = 25/244 (10%)
Query 868 RLQPHNLADVLTVNPDSP--------ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919
+LQ N D++ + D+P A++P +LK + +G G F CY
Sbjct 1188 QLQVENGEDIIIIQQDTPETLPGHTKANEPYREDTEWLKG-QQIGLGAFSS----CYQAQ 1242
Query 920 NDGTGEMVAVKAL---KADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGC-CEDQGEKS 973
+ GTG ++AVK + + Q ++EI ++ L H +II+ G CE + +
Sbjct 1243 DVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCE---KSN 1299
Query 974 LQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032
L +E++ S+ L ++ +++ + +Q+ G++YLH IHRD+ N+L+D
Sbjct 1300 YNLFIEWMAGASVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLID 1359
Query 1033 ND-RLVKIGDFG-LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
+ + ++I DFG A+ +G + + + APE L+ ++ + DVWS G
Sbjct 1360 STGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCA 1419
Query 1091 LYEL 1094
+ E+
Sbjct 1420 IIEM 1423
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 52/227 (23%), Positives = 94/227 (41%), Gaps = 16/227 (7%)
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHG-VCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
++ A E +MS ++H ++ + G C + N+ + E++ G L + G
Sbjct 1265 QEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFI-EWMA-GASVAHLLSKYGAF 1322
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF---IKLSDPGVG 763
+ + +QL LSYL ++H +V G N+L+ G + F +L+ G G
Sbjct 1323 KESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTG 1382
Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE- 822
G + + + I ++APE L G + D W G ++E+ + P + S
Sbjct 1383 AGEF-QGQLLGTIAFMAPEVLRG--QQYGRSCDVWSVGCAIIEMAC-AKPPWNAEKHSNH 1438
Query 823 -----KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
K +P P L + +CL +P RP R +L+
Sbjct 1439 LALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLK 1485
>sp|Q5REX1|SIK2_PONAB Serine/threonine-protein kinase SIK2 OS=Pongo
abelii OX=9601 GN=SIK2 PE=2 SV=1
Length=925
Score = 80.9 bits (198), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 63/196 (32%), Positives = 91/196 (46%), Gaps = 13/196 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG+G+F V L + T VA+K + K+ + +E+ I++ L H HIIK
Sbjct 26 LGKGNFAVVKLGRHRITKTE----VAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIK 81
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020
E + L LV EY G + DYL H + ++ QI + Y H + +
Sbjct 82 LYQVMETKS--MLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIV 139
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDL A N+LLDN+ +KI DF G R G P + APE + ++
Sbjct 140 HRDLKAENLLLDNNMNIKIADFSFGNFFKSGELLATWR--GSPP--YAAPEVFEGQQYEG 195
Query 1081 AS-DVWSFGVTLYELL 1095
D+WS GV LY L+
Sbjct 196 PQLDIWSMGVVLYVLV 211
Score = 45.4 bits (106), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 48/192 (25%), Positives = 78/192 (41%), Gaps = 19/192 (10%)
Query 630 GRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
GR R + V +K++D S D Y +M + H H+ ++ V +VT
Sbjct 37 GRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVT 96
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
EY ++G + +L G + + Q+ SA+ Y + +VH ++ N+LL
Sbjct 97 EYAKNGEIFDYLAN-HGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLL----- 150
Query 748 AEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+ IK++D G S E P+ APE G +D W G L
Sbjct 151 --DNNMNIKIADFSFGNFFKSGELLATWRGSPPYAAPEVFEGQQYE-GPQLDIWSMGVVL 207
Query 805 -LEIC----FDG 811
+ +C FDG
Sbjct 208 YVLVCGALPFDG 219
>sp|Q7X8C5|WAKLB_ARATH Wall-associated receptor kinase-like 2
OS=Arabidopsis thaliana OX=3702 GN=WAKL2 PE=2 SV=1
Length=748
Score = 80.5 bits (197), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 60/181 (33%), Positives = 87/181 (48%), Gaps = 14/181 (8%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
G +VAVK KA + E+ +L + H +I+K GCC + + LV E+VP
Sbjct 438 GRIVAVKRSKA-VDEDRVEEFINEVVVLAQINHRNIVKLLGCCLET--EVPVLVYEFVPN 494
Query 984 GSL----RDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI---HRDLAARNVLLDNDRL 1036
G L D +++ L A +I ++YLH+ HRD+ N+LLD
Sbjct 495 GDLCKRLHDESDDYTMTWEVRLHIAIEIAGALSYLHSAASFPIYHRDIKTTNILLDERNR 554
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA-PECLKEYKFYYASDVWSFGVTLYELL 1095
K+ DFG +++V + + G F Y PE + KF SDV+SFGV L ELL
Sbjct 555 AKVSDFGTSRSVTIDQTHLTTQVAG---TFGYVDPEYFQSSKFTEKSDVYSFGVVLVELL 611
Query 1096 T 1096
T
Sbjct 612 T 612
Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 70/305 (23%), Positives = 122/305 (40%), Gaps = 65/305 (21%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LGQG + VY+G L V GR V +K D
Sbjct 422 LGQGGQGTVYKGML-------------------VDGR------IVAVKRSKAVDEDRVEE 456
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712
F +++Q++H ++ + G C+ ++V E+V +G L L E M W ++
Sbjct 457 FINEVVVLAQINHRNIVKLLGCCLETEVPVLVYEFVPNGDLCKRLHDESDDYTMTWEVRL 516
Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+A ++A ALSYL + + H ++ NILL A K+SD G
Sbjct 517 HIAIEIAGALSYLHSAASFPIYHRDIKTTNILLDERNRA-------KVSDFGTSRSVTID 569
Query 770 EERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ + ++ PE ++ + D + FG L+E+ GE P SR SE+
Sbjct 570 QTHLTTQVAGTFGYVDPEYFQ--SSKFTEKSDVYSFGVVLVEL-LTGEKP-SSRVRSEEN 625
Query 825 -----HFYQ--RQHRLPE------------PSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
HF + +++R+ + +A L +CL + +RP+ R + +
Sbjct 626 RGLAAHFVEAVKENRVLDIVDDRIKDECNMDQVMSVANLARRCLNRKGKKRPNMREVSIE 685
Query 866 LTRLQ 870
L ++
Sbjct 686 LEMIR 690
>sp|Q39202|RLK1_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase RLK1 OS=Arabidopsis thaliana OX=3702 GN=RLK1
PE=2 SV=2
Length=832
Score = 80.5 bits (197), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 78/291 (27%), Positives = 127/291 (44%), Gaps = 16/291 (5%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+LG G FG V Y G+ VAVK L + +K E+ ++ ++H+++++
Sbjct 536 ELGRGAFGIV-YKGYLEVAGGSEVTVAVKKLDR-LDLDNEKEFKNEVKVIGQIHHKNLVR 593
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH--- 1015
G C + +S +V E++P G+L ++L PR S + + A I G+ YLH
Sbjct 594 LIGFCNEG--QSQMIVYEFLPQGTLANFLFRRPRPSWEDRKNIAVA--IARGILYLHEEC 649
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
++ IH D+ +N+LLD +I DFGLAK + Y G + APE +
Sbjct 650 SEQIIHCDIKPQNILLDEYYTPRISDFGLAKLLLMNQTYTLTNIRGTKG--YVAPEWFRN 707
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
DV+S+GV L E++ C + LI A RL +L E
Sbjct 708 SPITSKVDVYSYGVMLLEIV--CCKKAVDLEDNVILINWAYDCFRQGRLEDLTEDDSEAM 765
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
+ + C + E RP N+ +L+ V + + PS +S
Sbjct 766 NDMETVERYVKIAIWCIQEEHGMRPNMRNVTQMLEGVIQVFDPPNPSPYST 816
Score = 51.2 bits (121), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 61/252 (24%), Positives = 108/252 (43%), Gaps = 45/252 (18%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
A + LNL ++ + + LG+G VY+G L V G
Sbjct 509 ATTTANELNLRVFTYGELAEATRDFTEELGRGAFGIVYKGYLEVAG-------------- 554
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
G E+ V +K LD D F ++ Q+ H +L + G C G ++V
Sbjct 555 -------GSEVTVAVKKLDRLDLDNEKEFKNEVKVIGQIHHKNLVRLIGFCNEGQSQMIV 607
Query 687 TEYVEHGPLDVWL-RRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNI 740
E++ G L +L RR R +W + +A +A + YL ++ ++H ++ +NI
Sbjct 608 YEFLPQGTLANFLFRRPRP----SWEDRKNIAVAIARGILYLHEECSEQIIHCDIKPQNI 663
Query 741 LLARLGLAEGTSPFIKLSDPGVG-LGALSREERVERI----PWLAPECLPGGANSLSTAM 795
L L E +P ++SD G+ L +++ + I ++APE +++ +
Sbjct 664 L-----LDEYYTP--RISDFGLAKLLLMNQTYTLTNIRGTKGYVAPEWFRNSP--ITSKV 714
Query 796 DKWGFGATLLEI 807
D + +G LLEI
Sbjct 715 DVYSYGVMLLEI 726
>sp|P50528|PLO1_SCHPO Serine/threonine-protein kinase plo1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=plo1 PE=1 SV=1
Length=683
Score = 80.5 bits (197), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 74/282 (26%), Positives = 123/282 (44%), Gaps = 33/282 (12%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ--E 947
+F+ RY +GEG F + C+ D G + A K + ++ K E
Sbjct 38 NIFYTRY----DCIGEGGFAR----CFR-VKDNYGNIYAAKVIAKRSLQNDKTKLKLFGE 88
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006
I + +++ H +I+ + C ED ++ L++E SL + L R + ++ Q
Sbjct 89 IKVHQSMSHPNIVGFIDCFEDST--NIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQ 146
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I + Y+H + IHRDL N++LD VKIGDFGLA + + E R +P
Sbjct 147 ILGALKYMHKKRVIHRDLKLGNIMLDESNNVKIGDFGLAALLMDDEE--RKMTICGTPN- 203
Query 1067 WYAPECLKEYK--FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+ APE L K + D+WS GV +Y LL PP + E+ T+ R
Sbjct 204 YIAPEILFNSKEGHSFEVDLWSAGVVMYALLI-----GKPPFQDKEV-------KTIYR- 250
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
++ P E L+ + + S RP+ ++++
Sbjct 251 -KIKANSYSFPSNVDISAEAKDLISSLLTHDPSIRPSIDDIV 291
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 51/198 (26%), Positives = 86/198 (43%), Gaps = 23/198 (12%)
Query 677 CVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNV 735
C NI ++ E EH L + L R+R + + Q+ AL Y+ K ++H
Sbjct 106 CFEDSTNIYLILELCEHKSL-MELLRKRKQLTEPEVRYLMMQILGALKYMHKKRVIH--- 161
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSL 791
R++ L + L E + +K+ D G+ + EER I ++APE L
Sbjct 162 --RDLKLGNIMLDESNN--VKIGDFGLAALLMDDEERKMTICGTPNYIAPEILFNSKEGH 217
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ--RQHRLPEPSCPQLAT----LT 845
S +D W G + + G+ P Q + E + Y+ + + PS ++ L
Sbjct 218 SFEVDLWSAGVVMYALLI-GKPPFQDK---EVKTIYRKIKANSYSFPSNVDISAEAKDLI 273
Query 846 SQCLTYEPTQRPSFRTIL 863
S LT++P+ RPS I+
Sbjct 274 SSLLTHDPSIRPSIDDIV 291
>sp|Q52EB3|ATG1_PYRO7 Serine/threonine-protein kinase ATG1 OS=Pyricularia
oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
OX=242507 GN=ATG1 PE=1 SV=1
Length=982
Score = 80.9 bits (198), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 76/317 (24%), Positives = 128/317 (40%), Gaps = 75/317 (24%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHII 960
++G+G F +V Y + +G VA+K+++ A + + EI+IL+TL H HI+
Sbjct 24 EIGKGSFAQV----YMGKHKVSGAAVAIKSVELARLNKKLKENLYGEINILKTLRHPHIV 79
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSL--------------------RDYLPRHSIGLAQL 1000
C E + L+MEY LG L R Y + GL ++
Sbjct 80 ALHDCVESATH--INLMMEYCELGDLSLFIKKREKLSTNPATHDMARKYPNVPNSGLNEV 137
Query 1001 LL--FAQQICEGMAYLHAQHYIHRDLAARNVLL-------------------DNDRLV-- 1037
++ F +Q+ + +L + +HRD+ +N+LL D LV
Sbjct 138 VIRHFLKQLSSALKFLRESNLVHRDVKPQNLLLLPSPEFREVNKLARPILTASQDSLVPV 197
Query 1038 ---------KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
K+ DFG A+ +P + E + APE L+ ++ +D+WS G
Sbjct 198 AGLASLPMLKLADFGFARVLPSTS----LAETLCGSPLYMAPEILRYERYDAKADLWSVG 253
Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148
L+E++ PP + A + +LR E E + PR E+ L
Sbjct 254 TVLFEMIVG-----RPPFR-------ASNHVELLRKIEAAEDVIKFPRETTISSEMKGLT 301
Query 1149 KNCWETEASFRPTFENL 1165
+ + R +FEN
Sbjct 302 RALLKRNPVERISFENF 318
Score = 40.4 bits (93), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 75/323 (23%), Positives = 126/323 (39%), Gaps = 86/323 (27%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
+ +G+G+ VY G+ +V G+ V +K ++ + +
Sbjct 23 AEIGKGSFAQVYMGKHKVSGAA------------------------VAIKSVELARLNKK 58
Query 653 LA--FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLR--------- 700
L Y +++ + H H+ +H CV +I ++ EY E G L ++++
Sbjct 59 LKENLYGEINILKTLRHPHIVALHD-CVESATHINLMMEYCELGDLSLFIKKREKLSTNP 117
Query 701 ------RERGHVPMAWKMVVA-----QQLASALSYLENKNLVHGNVCGRNIL-------- 741
R+ +VP + V +QL+SAL +L NLVH +V +N+L
Sbjct 118 ATHDMARKYPNVPNSGLNEVVIRHFLKQLSSALKFLRESNLVHRDVKPQNLLLLPSPEFR 177
Query 742 ----LAR-------------LGLAEGTSPFIKLSDPGVG--LGALSREERVERIP-WLAP 781
LAR GLA + P +KL+D G L + S E + P ++AP
Sbjct 178 EVNKLARPILTASQDSLVPVAGLA--SLPMLKLADFGFARVLPSTSLAETLCGSPLYMAP 235
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE---KEHFYQRQHRLPEPSC 838
E L D W G L E+ G P ++ + E K + + P +
Sbjct 236 EIL--RYERYDAKADLWSVGTVLFEMIV-GRPPFRASNHVELLRKIEAAEDVIKFPRETT 292
Query 839 --PQLATLTSQCLTYEPTQRPSF 859
++ LT L P +R SF
Sbjct 293 ISSEMKGLTRALLKRNPVERISF 315
>sp|A9TF79|SRK2A_PHYPA Serine/threonine-protein kinase SRK2A OS=Physcomitrium
patens OX=3218 GN=SRK2A PE=1 SV=1
Length=349
Score = 78.6 bits (192), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 79/231 (34%), Positives = 114/231 (49%), Gaps = 27/231 (12%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
H RY + ++D+G G+FG L + T E+VAVK ++ G + ++EI R
Sbjct 9 HDRY-ELVKDIGSGNFGVARLM----RDKKTRELVAVKYIER--GEKIDENVQREIINHR 61
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009
+L H +I+++K L +VMEY G L + + R S A+ F QQ+
Sbjct 62 SLRHPNIVRFKEVM--LTPTHLAIVMEYAAGGELFERICNAGRFSEDEARF--FFQQLIS 117
Query 1010 GMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G++Y H+ HRDL N LLD RL KI DFG +K+ + + + +P
Sbjct 118 GVSYCHSMQICHRDLKLENTLLDGSPAPRL-KICDFGYSKS---SLLHSQPKSTVGTPA- 172
Query 1067 WYAPECL--KEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLELIG 1113
+ APE L KEY A DVWS GVTLY +L + P P F + IG
Sbjct 173 YIAPEVLSKKEYDGKIA-DVWSCGVTLYVMLVGAYPFEDPEDPRNFRKTIG 222
>sp|P34101|FHKC_DICDI Probable serine/threonine-protein kinase
fhkC OS=Dictyostelium discoideum OX=44689 GN=fhkC PE=3 SV=2
Length=595
Score = 80.1 bits (196), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 74/220 (34%), Positives = 103/220 (47%), Gaps = 20/220 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL---KADCGPQHRSGWKQEIDILRTLYHEHI 959
LG G+F V L TG A+K + K + + E+++L + H++I
Sbjct 224 LGTGNFASVRL----GVEKETGNKYAIKIIDKKKMSMTSKRKDSLMDEVNVLTKVKHQNI 279
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I K E Q K+L LV+E V G L D + +Q+C+ + YLH+
Sbjct 280 ISIKEVFETQ--KNLYLVLELVTGGELFDKIVSERKFQEDTCRYILKQLCDSVRYLHSNG 337
Query 1019 YIHRDLAARNVLLD--NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK-- 1074
HRDL N+LL N L+KI DFGL++A+ EG Y + +P + APE L
Sbjct 338 IAHRDLKPENILLATPNSFLLKISDFGLSRAMDEGT-YMKTM--CGTPQY-VAPEILTKG 393
Query 1075 EYKFYYAS-DVWSFGVTLYELLTHCDSSQSPPTK-FLELI 1112
E + Y S D+WS GV Y LL P TK F E I
Sbjct 394 EREGYGKSVDLWSIGVITYILLCGFPPFGDPQTKDFFEKI 433
>sp|Q8N5S9|KKCC1_HUMAN Calcium/calmodulin-dependent protein kinase
kinase 1 OS=Homo sapiens OX=9606 GN=CAMKK1 PE=1 SV=2
Length=505
Score = 79.7 bits (195), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 50/150 (33%), Positives = 79/150 (53%), Gaps = 6/150 (4%)
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ 1005
QEI IL+ L H +++K +D E +L LV + + G + + Q L+ +
Sbjct 198 QEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFSEEQARLYLR 257
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
+ G+ YLH Q +HRD+ N+LL +D VKI DFG++ EG++ ++ +P
Sbjct 258 DVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF-EGND-AQLSSTAGTPA 315
Query 1066 FWYAPECLKEYKFYY---ASDVWSFGVTLY 1092
F APE + + + A DVW+ GVTLY
Sbjct 316 FM-APEAISDSGQSFSGKALDVWATGVTLY 344
>sp|Q9LUL4|SRF7_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 7 OS=Arabidopsis
thaliana OX=3702 GN=SRF7 PE=1 SV=1
Length=717
Score = 80.5 bits (197), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 73/278 (26%), Positives = 130/278 (47%), Gaps = 41/278 (15%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-WKQEIDILRTLYHEHIIK 961
LGEG FG+V ++ G+++AVK + + P + + + + + L HE++ K
Sbjct 425 LGEGTFGRVYRAQFE-----DGKVLAVKKIDSSALPTDTADDFTEIVSKIAHLDHENVTK 479
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------------PRHSI--GLAQLLLFAQQ 1006
G C + G+ +V E+ GSL D+L PR I G A+ L + +
Sbjct 480 LDGYCSEHGQH--LVVYEFHRNGSLHDFLHLAEEESKPLIWNPRVKIALGTARALEYLHE 537
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+C + +H+++ + N+LLD++ + D GLA +P +E ++G
Sbjct 538 VC-------SPSIVHKNIKSANILLDSELNPHLSDSGLASFLPTANELLNQNDEG----- 585
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQM-TVL 1122
+ APE ++ SDV+SFGV + ELLT DS++S + L+ A Q+ +
Sbjct 586 YSAPETSMSGQYSLKSDVYSFGVVMLELLTGRKPFDSTRSRSEQ--SLVRWATPQLHDID 643
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
L ++++ + P K ++ C + E FRP
Sbjct 644 ALGKMVDPALKGLYPVKSLSRFADVIALCVQPEPEFRP 681
>sp|Q9DG98|CDK1_ORYLU Cyclin-dependent kinase 1 OS=Oryzias luzonensis
OX=104659 GN=cdk1 PE=2 SV=1
Length=303
Score = 77.8 bits (190), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 66/215 (31%), Positives = 109/215 (51%), Gaps = 25/215 (12%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957
KI +GEG +G V Y + TG++VA+K ++ + + S +E+ +L+ L H
Sbjct 6 KIEKIGEGTYGVV----YKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLL--FAQQICEGMAY 1013
++++ E L L+ E++ + L+ YL G + +L+ + QI EG+ +
Sbjct 62 NVVRLLDVL--MQESRLYLIFEFLSM-DLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWYAPE 1071
H + +HRDL +N+L+DN ++K+ DFGLA+A VP RV +++ APE
Sbjct 119 CHRRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVP-----VRVYTHEVVTLWYRAPE 173
Query 1072 C-LKEYKFYYASDVWSFGVTLYELLT-----HCDS 1100
L ++ DVWS G EL T H DS
Sbjct 174 VLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDS 208
>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase
OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1
Length=1235
Score = 80.9 bits (198), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 60/205 (29%), Positives = 99/205 (48%), Gaps = 23/205 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I +LG+G FGKV Y N T + A K + + + EIDIL + H +I
Sbjct 37 IGELGDGAFGKV----YKAQNKETSVLAAAKVIDTK-SEEELEDYMVEIDILASCDHPNI 91
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQ 1017
+K E +L +++E+ G++ + + +Q+ + +Q + + YLH
Sbjct 92 VKLLDAF--YYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDN 149
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---FWYAPECL- 1073
IHRDL A N+L D +K+ DFG++ + R + DS + +W APE +
Sbjct 150 KIIHRDLKAGNILFTLDGDIKLADFGVS------AKNTRTIQRRDSFIGTPYWMAPEVVM 203
Query 1074 ----KEYKFYYASDVWSFGVTLYEL 1094
K+ + Y +DVWS G+TL E+
Sbjct 204 CETSKDRPYDYKADVWSLGITLIEM 228
Score = 40.4 bits (93), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 31/103 (30%), Positives = 44/103 (43%), Gaps = 14/103 (14%)
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG---ALSR 769
VV +Q AL+YL + ++H ++ NIL G IKL+D GV + R
Sbjct 134 VVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDG-------DIKLADFGVSAKNTRTIQR 186
Query 770 EERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808
+ P W+APE C D W G TL+E+
Sbjct 187 RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMA 229
>sp|Q21734|KS6A1_CAEEL Putative ribosomal protein S6 kinase alpha-1
OS=Caenorhabditis elegans OX=6239 GN=rskn-1 PE=3 SV=4
Length=784
Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 61/205 (30%), Positives = 103/205 (50%), Gaps = 10/205 (5%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRT 953
R + ++ LG+G FGKV L D +G + A+K LK A + R K E +IL
Sbjct 102 RQFELLKVLGQGSFGKVFLVRKVRGRD-SGHVYAMKVLKKATLKVRDRQRTKLERNILAH 160
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ-LLLFAQQICEGMA 1012
+ H I+K + +G+ L L+++++ G L L + + + + ++ +
Sbjct 161 ISHPFIVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALE 218
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK-AVPEGHEYYRVREDGDSPVFWYAPE 1071
+LH+ ++RDL N+LLD D +K+ DFGL+K A+ + Y V + APE
Sbjct 219 HLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFC----GTVEYMAPE 274
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
+ A+D WS GV ++E+LT
Sbjct 275 VINRRGHSMAADFWSLGVLMFEMLT 299
Score = 67.8 bits (164), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 26/191 (14%)
Query 946 QEIDIL-RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGL-AQLLL 1002
+E+DIL R +H+ ++K ED E ++ ++ E G L D L + S+G ++
Sbjct 494 EEVDILLRHSHHQFVVKLFDVYED--ETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAA 551
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLL---DND-RLVKIGDFGLAKAVPEGHEYYRVR 1058
+ + YLH+Q HRDL A N+L D D ++I DFG AK
Sbjct 552 IMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRA-------- 603
Query 1059 EDGD--SPVF---WYAPECLKEYKFYYASDVWSFGVTLYELLTHCD----SSQSPPTKFL 1109
E+G +P + + APE L++ + + DVWS GV L+ +LT C P + L
Sbjct 604 ENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQIL 663
Query 1110 ELIGIAQGQMT 1120
+ +G + MT
Sbjct 664 QRVGDGKISMT 674
>sp|G4N6Z6|MKK2_PYRO7 Mitogen-activated protein kinase kinae MKK2
OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC
8958) OX=242507 GN=MKK2 PE=1 SV=1
Length=527
Score = 79.7 bits (195), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 83/181 (46%), Gaps = 9/181 (5%)
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
G + A+K + A+ P + +E+D EHI +Y G ED ++ + ME+
Sbjct 248 GGKTVFALKVITANPDPDVKKQIMRELDFNIQCASEHICRYYGAFEDPSTATISIAMEFC 307
Query 982 PLGSLRDYLPR-----HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036
GSL G L A+ + G+ YL+++ IHRD+ N+LL +
Sbjct 308 EGGSLDSIYKEVKRLGGRTGEKVLGKIAEGVLRGLTYLNSKKIIHRDIKPSNILLCRNGD 367
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
VK+ DFG++ E G S ++ APE + + SDVWS GVTL E+
Sbjct 368 VKLCDFGVSGDFGTKGEANTFI--GTS--YYMAPERITGQSYTITSDVWSTGVTLLEVAQ 423
Query 1097 H 1097
H
Sbjct 424 H 424
Score = 44.3 bits (103), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 46/181 (25%), Positives = 78/181 (43%), Gaps = 22/181 (12%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT---EYVEHG 693
L+V+ DP D+ Q + H+ +G P ++ E+ E G
Sbjct 255 LKVITANPDP---DVKKQIMRELDFNIQCASEHICRYYG-AFEDPSTATISIAMEFCEGG 310
Query 694 PLDVW---LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
LD ++R G +A+ + L+YL +K ++H ++ NILL R G
Sbjct 311 SLDSIYKEVKRLGGRTGEKVLGKIAEGVLRGLTYLNSKKIIHRDIKPSNILLCRNG---- 366
Query 751 TSPFIKLSDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+KL D GV ++ E I ++APE + G + ++++ D W G TLLE+
Sbjct 367 ---DVKLCDFGVSGDFGTKGEANTFIGTSYYMAPERITGQSYTITS--DVWSTGVTLLEV 421
Query 808 C 808
Sbjct 422 A 422
>sp|Q9DGD3|CDK1_ORYLA Cyclin-dependent kinase 1 OS=Oryzias latipes
OX=8090 GN=cdk1 PE=2 SV=1
Length=303
Score = 77.8 bits (190), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 66/215 (31%), Positives = 109/215 (51%), Gaps = 25/215 (12%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957
KI +GEG +G V Y + TG++VA+K ++ + + S +E+ +L+ L H
Sbjct 6 KIEKIGEGTYGVV----YKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLL--FAQQICEGMAY 1013
++++ E L L+ E++ + L+ YL G + +L+ + QI EG+ +
Sbjct 62 NVVRLLDVL--MQESRLYLIFEFLSM-DLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWYAPE 1071
H + +HRDL +N+L+DN ++K+ DFGLA+A VP RV +++ APE
Sbjct 119 CHRRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVP-----VRVYTHEVVTLWYRAPE 173
Query 1072 C-LKEYKFYYASDVWSFGVTLYELLT-----HCDS 1100
L ++ DVWS G EL T H DS
Sbjct 174 VLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDS 208
>sp|Q95KV1|IKKA_BOVIN Inhibitor of nuclear factor kappa-B kinase
subunit alpha OS=Bos taurus OX=9913 GN=CHUK PE=1 SV=1
Length=740
Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 62/206 (30%), Positives = 95/206 (46%), Gaps = 24/206 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V LY + + +A+K+ + + ++R W EI I++ L H +++K
Sbjct 21 LGTGGFGNVCLYQHRELDLK----IAIKSCRLELSTKNRERWCHEIQIMKKLNHANVVK- 75
Query 963 KGCCEDQGEKSLQ------LVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMA 1012
C+ E + L MEY G LR L P + GL +Q+L I G+
Sbjct 76 --ACDVPEELNFLINDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIR 133
Query 1013 YLHAQHYIHRDLAARNVLLDN---DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH IHRDL N++L + + KI D G AK V +G + + + A
Sbjct 134 YLHENKIIHRDLKPENIVLQDVGGKIMHKIIDLGYAKDVDQG----SLCTSFVGTLQYLA 189
Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095
PE + + D WSFG ++E +
Sbjct 190 PELFENKPYTATVDYWSFGTMVFECI 215
>sp|Q9LIG2|RLK6_ARATH Receptor-like protein kinase At3g21340 OS=Arabidopsis
thaliana OX=3702 GN=At3g21340 PE=1 SV=1
Length=899
Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 63/204 (31%), Positives = 104/204 (51%), Gaps = 16/204 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LG+G FG V Y T + T E VAVK L ++ +K E+++L ++H++++
Sbjct 596 RVLGKGGFGMV----YHGTVNNT-EQVAVKMLSHSSSQGYKE-FKAEVELLLRVHHKNLV 649
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLHA 1016
G C D+GE +L L+ EY+ G LR+++ G L + +G+ YLH
Sbjct 650 GLVGYC-DEGE-NLALIYEYMANGDLREHMSGKRGGSILNWETRLKIVVESAQGLEYLHN 707
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+HRD+ N+LL+ K+ DFGL+++ P E + +P + PE
Sbjct 708 GCKPPMVHRDVKTTNILLNEHLHAKLADFGLSRSFPIEGETHVSTVVAGTPGY-LDPEYY 766
Query 1074 KEYKFYYASDVWSFGVTLYELLTH 1097
+ SDV+SFG+ L E++T+
Sbjct 767 RTNWLNEKSDVYSFGIVLLEIITN 790
Score = 46.6 bits (109), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 64/239 (27%), Positives = 97/239 (41%), Gaps = 35/239 (15%)
Query 599 TRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYET 658
T TN +E L G G G +++ + +V +K+L S F
Sbjct 589 TMTNNFERVLGKGGFGMVYHGTVNNTE------------QVAVKMLSHSSSQGYKEFKAE 636
Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQ 716
L+ +V H +L + G C G ++ EY+ +G L + +RG + W ++ +
Sbjct 637 VELLLRVHHKNLVGLVGYCDEGENLALIYEYMANGDLREHMSGKRGGSILNWETRLKIVV 696
Query 717 QLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREER 772
+ A L YL N +VH +V NILL A KL+D G+ + E
Sbjct 697 ESAQGLEYLHNGCKPPMVHRDVKTTNILLNEHLHA-------KLADFGLSRSFPIEGETH 749
Query 773 VERIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
V + +L PE N L+ D + FG LLEI + QSR EK H
Sbjct 750 VSTVVAGTPGYLDPEYYR--TNWLNEKSDVYSFGIVLLEIITNQLVINQSR---EKPHI 803
>sp|Q69JN6|BRL1_ORYSJ Brassinosteroid LRR receptor kinase BRL1
OS=Oryza sativa subsp. japonica OX=39947 GN=BRL1 PE=2 SV=1
Length=1214
Score = 80.9 bits (198), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 81/301 (27%), Positives = 133/301 (44%), Gaps = 34/301 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG+V G +VA+K L G R + E++ + + H +++
Sbjct 918 IGSGGFGEVY-----KAKLKDGSVVAIKKLIHFTGQGDRE-FTAEMETIGKIKHRNLVPL 971
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-------FAQQICEGMAYLH 1015
G C+ E+ LV EY+ GSL L H A + L A G+A+LH
Sbjct 972 LGYCKIGDER--LLVYEYMKHGSLDVVL--HDKAKASVKLDWSARKKIAIGSARGLAFLH 1027
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
H IHRD+ + NVLLDN+ ++ DFG+A+ + + V +P + PE
Sbjct 1028 HSCIPHIIHRDMKSSNVLLDNNLDARVSDFGMARLMNALDTHLSVSTLAGTP-GYVPPEY 1086
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLE--LIGIAQGQMTVLRLTELL 1128
+ ++ DV+S+GV L ELL S + P PT+F + L+G + + R +E+
Sbjct 1087 YQSFRCTTKGDVYSYGVVLLELL----SGKKPIDPTEFGDNNLVGWVKQMVKENRSSEIF 1142
Query 1129 ERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
+ L E+Y +K C + + RPT ++ + K + FS
Sbjct 1143 D--PTLTDRKSGEAELYQYLKIACECLDDRPNRRPTMIQVMAMFKELQLDSDSDILDGFS 1200
Query 1186 V 1186
+
Sbjct 1201 I 1201
Score = 44.7 bits (104), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 55/252 (22%), Positives = 103/252 (41%), Gaps = 36/252 (14%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAW--K 711
F + ++ H +L + G C G E ++V EY++HG LDV L + + V + W +
Sbjct 953 FTAEMETIGKIKHRNLVPLLGYCKIGDERLLVYEYMKHGSLDVVLHDKAKASVKLDWSAR 1012
Query 712 MVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGA 766
+A A L++L + +++H ++ N+LL + ++SD G+ + A
Sbjct 1013 KKIAIGSARGLAFLHHSCIPHIIHRDMKSSNVLLDN-------NLDARVSDFGMARLMNA 1065
Query 767 LSREERVERIPWLAPECLPGGANSL--STAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
L V + P S +T D + +G LLE+ G+ P+ +
Sbjct 1066 LDTHLSVSTLAGTPGYVPPEYYQSFRCTTKGDVYSYGVVLLEL-LSGKKPIDPTEFGDNN 1124
Query 825 HF-----YQRQHRLPEPSCPQLA-------------TLTSQCLTYEPTQRPSFRTILRDL 866
+++R E P L + +CL P +RP+ ++
Sbjct 1125 LVGWVKQMVKENRSSEIFDPTLTDRKSGEAELYQYLKIACECLDDRPNRRPTMIQVMAMF 1184
Query 867 TRLQPHNLADVL 878
LQ + +D+L
Sbjct 1185 KELQLDSDSDIL 1196
>sp|Q9SYM9|Y1853_ARATH Receptor-like serine/threonine-protein
kinase At1g78530 OS=Arabidopsis thaliana OX=3702 GN=At1g78530
PE=2 SV=1
Length=355
Score = 78.6 bits (192), Expect = 6e-14, Method: Composition-based stats.
Identities = 84/290 (29%), Positives = 128/290 (44%), Gaps = 25/290 (9%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
HK K I LG G FG V D D T AVK L + R G+ +E++ +
Sbjct 73 HKLSNKDI--LGSGGFGTVYRLVID---DST--TFAVKRLNRGTSERDR-GFHRELEAMA 124
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGM 1011
+ H +I+ G L+ E +P GSL +L R ++ A A G+
Sbjct 125 DIKHRNIVTLHGYFTSPHYN--LLIYELMPNGSLDSFLHGRKALDWASRYRIAVGAARGI 182
Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+YLH H IHRD+ + N+LLD++ ++ DFGLA + + G F Y
Sbjct 183 SYLHHDCIPHIIHRDIKSSNILLDHNMEARVSDFGLATLMEPDKTHVSTFVAG---TFGY 239
Query 1069 -APECLKEYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELI-GIAQGQMTVL 1122
APE K DV+SFGV L ELLT D TK + + G+ + Q +
Sbjct 240 LAPEYFDTGKATMKGDVYSFGVVLLELLTGRKPTDDEFFEEGTKLVTWVKGVVRDQREEV 299
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ L RG + ++ +V+ + C E E + RP ++ +L+ +
Sbjct 300 VIDNRL-RGSSVQENEEMN-DVFGIAMMCLEPEPAIRPAMTEVVKLLEYI 347
Score = 45.1 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 45/183 (25%), Positives = 78/183 (43%), Gaps = 29/183 (16%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F+ M+ + H ++ +HG N+++ E + +G LD +L R + A +
Sbjct 115 GFHRELEAMADIKHRNIVTLHGYFTSPHYNLLIYELMPNGSLDSFL-HGRKALDWASRYR 173
Query 714 VAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+A A +SYL + +++H ++ NILL A ++SD GL L
Sbjct 174 IAVGAARGISYLHHDCIPHIIHRDIKSSNILLDHNMEA-------RVSD--FGLATLMEP 224
Query 771 ERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
++ +LAPE G ++ D + FG LLE+ L R P++
Sbjct 225 DKTHVSTFVAGTFGYLAPEYFDTGKATMKG--DVYSFGVVLLEL-------LTGRKPTDD 275
Query 824 EHF 826
E F
Sbjct 276 EFF 278
>sp|Q9SI06|Y5573_ARATH Putative leucine-rich repeat receptor-like
serine/threonine-protein kinase At2g04300 OS=Arabidopsis
thaliana OX=3702 GN=At2g04300 PE=3 SV=2
Length=892
Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 64/204 (31%), Positives = 106/204 (52%), Gaps = 20/204 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V + ND E VAVK L ++ +K E+++L ++H++++
Sbjct 588 LGKGGFGMV---YHGTVNDA--EQVAVKMLSPSSSQGYKE-FKAEVELLLRVHHKNLVGL 641
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017
G C D+GE +L L+ EY+ G L++++ + G++ L L + +G+ YLH
Sbjct 642 VGYC-DEGE-NLSLIYEYMAKGDLKEHMLGNQ-GVSILDWKTRLKIVAESAQGLEYLHNG 698
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECL 1073
+HRD+ N+LLD K+ DFGL+++ P EG RV + PE
Sbjct 699 CKPPMVHRDVKTTNILLDEHFQAKLADFGLSRSFPLEGET--RVDTVVAGTPGYLDPEYY 756
Query 1074 KEYKFYYASDVWSFGVTLYELLTH 1097
+ SDV+SFG+ L E++T+
Sbjct 757 RTNWLNEKSDVYSFGIVLLEIITN 780
Score = 54.3 bits (129), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 67/237 (28%), Positives = 97/237 (41%), Gaps = 35/237 (15%)
Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660
TN +E L G G G ++D + +V +K+L PS F
Sbjct 581 TNNFEKILGKGGFGMVYHGTVNDAE------------QVAVKMLSPSSSQGYKEFKAEVE 628
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK--MVVAQQL 718
L+ +V H +L + G C G ++ EY+ G L + +G + WK + + +
Sbjct 629 LLLRVHHKNLVGLVGYCDEGENLSLIYEYMAKGDLKEHMLGNQGVSILDWKTRLKIVAES 688
Query 719 ASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVE 774
A L YL N +VH +V NILL A KL+D G+ L E RV+
Sbjct 689 AQGLEYLHNGCKPPMVHRDVKTTNILLDEHFQA-------KLADFGLSRSFPLEGETRVD 741
Query 775 RIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ +L PE N L+ D + FG LLEI + QSR EK H
Sbjct 742 TVVAGTPGYLDPEYYR--TNWLNEKSDVYSFGIVLLEIITNQHVINQSR---EKPHI 793
>sp|Q5XIT0|CDKL2_RAT Cyclin-dependent kinase-like 2 OS=Rattus
norvegicus OX=10116 GN=Cdkl2 PE=2 SV=1
Length=507
Score = 79.7 bits (195), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 60/198 (30%), Positives = 101/198 (51%), Gaps = 16/198 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG +G V + C N +G +VA+K L++D + +EI +L+ L HE+++
Sbjct 10 VGEGSYGMV-MKC---RNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65
Query 962 YKGCCEDQGEKSLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
C+ + K LV E+V L L+ + + Q LF QI G+ + H+ +
Sbjct 66 LLEVCKKK--KRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLF--QIINGIGFCHSHN 121
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEYK 1077
IHRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L + K
Sbjct 122 IIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVK 178
Query 1078 FYYASDVWSFGVTLYELL 1095
+ A D+W+ G + E+L
Sbjct 179 YGKAVDIWAIGCLVIEML 196
Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 58/238 (24%), Positives = 98/238 (41%), Gaps = 54/238 (23%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ---- 716
L+ Q+ H +L + VC + +V E+V+H LD + P V Q
Sbjct 54 LLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILD-----DLKLFPNGLDYQVVQKYLF 108
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVER 775
Q+ + + + + N++H ++ NIL+++ G+ +KL D G A E +
Sbjct 109 QIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFARTLAAPGEVYTDY 161
Query 776 IP---WLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGEAP----------LQS 817
+ + APE L G A+D W G ++E+ F GE+ L +
Sbjct 162 VATRWYRAPELLVGDV-KYGKAVDIWAIGCLVIEMLMGQPLFPGESDIDQLHHIMTCLGN 220
Query 818 RSPSEKEHFYQR----QHRLPE-------------PSCPQLA-TLTSQCLTYEPTQRP 857
P +E FY+ RLPE P P++ +L +CL +P +RP
Sbjct 221 LIPRHQELFYKNPVFAGVRLPEIKDIEAEPLESRYPKLPEVVISLAKKCLHIDPDKRP 278
>sp|Q38773|CDC2B_ANTMA Cell division control protein 2 homolog
B (Fragment) OS=Antirrhinum majus OX=4151 GN=CDC2B PE=2 SV=1
Length=280
Score = 77.4 bits (189), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 66/212 (31%), Positives = 99/212 (47%), Gaps = 21/212 (10%)
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
Y + T E +A+K ++ + + S +EI +L+ ++HE+I+ K EK
Sbjct 5 VYKARDIETNEDIALKKIRLEQEDEGVPSTAIREISLLKEMHHENIVNLKDVV--HREKR 62
Query 974 LQLVMEYVPLGSLR--DYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031
L LV EY+ L + D P S L + +F QI G+AY H+ +HRDL +N+L+
Sbjct 63 LYLVFEYLDLDLKKHMDSCPEFSQDLHMVKMFLCQILRGVAYCHSHRVLHRDLKPQNLLI 122
Query 1032 DN-DRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-APECLKEYKFYYA-SDVWS 1086
D +K+ DFGLA+A +P + V WY APE L + Y DVWS
Sbjct 123 DRGSNTIKLADFGLARAFGIPVRTFTHEVV------TLWYRAPEVLLGSRHYSTPVDVWS 176
Query 1087 FGVTLYELLTH-----CDSSQSPPTKFLELIG 1113
G E++ DS K +IG
Sbjct 177 VGCIFAEMVNQKPLFPGDSEIDELHKIFRIIG 208
>sp|Q8BGW6|ST32A_MOUSE Serine/threonine-protein kinase 32A OS=Mus
musculus OX=10090 GN=Stk32a PE=2 SV=1
Length=398
Score = 79.0 bits (193), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 82/262 (31%), Positives = 125/262 (48%), Gaps = 42/262 (16%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQH--RSGWKQEIDILRTLYH 956
+R +G+G FGKV C ND T +M A+K + K C ++ R+ +K E+ I++ L H
Sbjct 26 LRAIGKGSFGKV---CIVRKND-TKKMYAMKYMNKQKCVERNEVRNVFK-ELQIMQGLEH 80
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLH 1015
++ +D E+ + +V++ + G LR +L ++ + LF ++ + YL
Sbjct 81 PFLVNLWYSFQD--EEDMFMVVDLLLGGDLRYHLQQNVHFQEDTVKLFICELAMALDYLQ 138
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-- 1073
+Q IHRD+ N+LLD V I DF +A +P+ V G P + APE
Sbjct 139 SQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPKETRITTVA--GTKP--YMAPEMFTS 194
Query 1074 -KEYKFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGI----------AQG 1117
KE + +A D WS GVT YELL H SS S E++ + A
Sbjct 195 RKETGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSK----EIVNMFETAIVTYPSAWS 250
Query 1118 QMTVLRLTELLERGERLPRPDK 1139
Q V L +LLE P PD+
Sbjct 251 QEMVSLLKKLLE-----PNPDQ 267
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 43/171 (25%), Positives = 73/171 (43%), Gaps = 18/171 (11%)
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI 776
+LA AL YL+++ ++H ++ NILL G + ++D + L +E R+ +
Sbjct 129 ELAMALDYLQSQRIIHRDMKPDNILLDEHG-------HVHITDFNIA-AMLPKETRITTV 180
Query 777 ----PWLAPECLPGGANS-LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH----FY 827
P++APE + S A+D W G T E+ G P RS + + F
Sbjct 181 AGTKPYMAPEMFTSRKETGYSFAVDWWSLGVTAYEL-LRGRRPYHIRSSTSSKEIVNMFE 239
Query 828 QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
P ++ +L + L P QR S T +++ + N VL
Sbjct 240 TAIVTYPSAWSQEMVSLLKKLLEPNPDQRFSHLTDIQNFPYMSDMNWDAVL 290
>sp|Q6ZCZ2|BRL3_ORYSJ Brassinosteroid LRR receptor kinase BRL3
OS=Oryza sativa subsp. japonica OX=39947 GN=BRL3 PE=2 SV=1
Length=1214
Score = 80.9 bits (198), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 82/285 (29%), Positives = 131/285 (46%), Gaps = 35/285 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG+V G +VAVK L G R + E++ + + H +++
Sbjct 919 IGSGGFGEVY-----KAKLKDGNIVAVKKLMHFTGQGDRE-FTAEMETIGKIKHRNLVPL 972
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-------FAQQICEGMAYLH 1015
G C+ E+ LV EY+ GSL L H G A + L A G+A+LH
Sbjct 973 LGYCKIGDER--LLVYEYMKNGSLDFVL--HDKGEANMDLNWATRKKIAIGSARGLAFLH 1028
Query 1016 ---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
H IHRD+ + NVLLD + + DFG+A+ + + V +P + PE
Sbjct 1029 HSCVPHIIHRDMKSSNVLLDGNFDAYVSDFGMARLMNALDSHLTVSMLSGTPG-YVPPEY 1087
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLE--LIGIAQGQMTVLRLTELL 1128
++++ DV+S+GV L ELLT + P PT+F + L+G + QM R +E+
Sbjct 1088 CQDFRCTTKGDVYSYGVVLLELLT----GKKPIDPTEFGDSNLVGWVK-QMVEDRCSEIY 1142
Query 1129 ERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170
+ L E+Y +K C + + + RPT ++ + K
Sbjct 1143 D--PTLMATTSSELELYQYLKIACRCLDDQPNRRPTMIQVMTMFK 1185
Score = 35.4 bits (80), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 58/263 (22%), Positives = 107/263 (41%), Gaps = 50/263 (19%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM----AW 710
F + ++ H +L + G C G E ++V EY+++G LD L ++G M A
Sbjct 954 FTAEMETIGKIKHRNLVPLLGYCKIGDERLLVYEYMKNGSLDFVL-HDKGEANMDLNWAT 1012
Query 711 KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LG 765
+ +A A L++L + +++H ++ N+LL +G +SD G+ +
Sbjct 1013 RKKIAIGSARGLAFLHHSCVPHIIHRDMKSSNVLL------DGNFD-AYVSDFGMARLMN 1065
Query 766 ALSREERVERIPWLAPECLPGGANSL--STAMDKWGFGATLLEICFDGEAPLQSRSPSE- 822
AL V + P +T D + +G LLE+ G+ P+ P+E
Sbjct 1066 ALDSHLTVSMLSGTPGYVPPEYCQDFRCTTKGDVYSYGVVLLEL-LTGKKPID---PTEF 1121
Query 823 ---------KEHFYQRQHRLPEPSCPQLATLTSQ------------CLTYEPTQRPSFRT 861
K+ R + +P+ +AT +S+ CL +P +RP+
Sbjct 1122 GDSNLVGWVKQMVEDRCSEIYDPTL--MATTSSELELYQYLKIACRCLDDQPNRRPTMIQ 1179
Query 862 ILRDLTRLQ---PHNLADVLTVN 881
++ Q N D ++N
Sbjct 1180 VMTMFKEFQVDSGSNFLDDFSLN 1202
>sp|Q9M345|LRK42_ARATH L-type lectin-domain containing receptor
kinase IV.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK42 PE=2
SV=1
Length=677
Score = 80.1 bits (196), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 66/200 (33%), Positives = 97/200 (49%), Gaps = 15/200 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG+V Y T VAVK + D Q + EI + + H +++
Sbjct 353 LGSGGFGRV----YRGILPTTKLEVAVKRVSHDS-KQGMKEFVAEIVSIGRMSHRNLVPL 407
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA--- 1016
G C +GE L LV +Y+P GSL YL P ++ Q + + G+ YLH
Sbjct 408 LGYCRRRGE--LLLVYDYMPNGSLDKYLYNNPETTLDWKQRSTIIKGVASGLFYLHEEWE 465
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
Q IHRD+ A NVLLD D ++GDFGLA+ G + G + + APE +
Sbjct 466 QVVIHRDVKASNVLLDADFNGRLGDFGLARLYDHGSDPQTTHVVG--TLGYLAPEHSRTG 523
Query 1077 KFYYASDVWSFGVTLYELLT 1096
+ +DV++FG L E+++
Sbjct 524 RATTTTDVYAFGAFLLEVVS 543
Score = 50.8 bits (120), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 61/235 (26%), Positives = 98/235 (42%), Gaps = 41/235 (17%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM--VVAQQLA 719
+ ++SH +L + G C R E ++V +Y+ +G LD +L + WK + + +A
Sbjct 396 IGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNNP-ETTLDWKQRSTIIKGVA 454
Query 720 SALSYLE---NKNLVHGNVCGRNILL-----ARLGLAEGTSPFIKLSDPGVGLGALSREE 771
S L YL + ++H +V N+LL RLG + SDP
Sbjct 455 SGLFYLHEEWEQVVIHRDVKASNVLLDADFNGRLGDFGLARLYDHGSDP-------QTTH 507
Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-- 829
V + +LAPE G + +T D + FGA LLE+ G P++ S S+
Sbjct 508 VVGTLGYLAPEHSRTGRATTTT--DVYAFGAFLLEVV-SGRRPIEFHSASDDTFLLVEWV 564
Query 830 -----QHRLPEPSCPQLAT-------------LTSQCLTYEPTQRPSFRTILRDL 866
+ + E P+L + L C +P RPS R +L+ L
Sbjct 565 FSLWLRGNIMEAKDPKLGSSGYDLEEVEMVLKLGLLCSHSDPRARPSMRQVLQYL 619
>sp|O65405|CRK28_ARATH Cysteine-rich receptor-like protein kinase
28 OS=Arabidopsis thaliana OX=3702 GN=CRK28 PE=3 SV=2
Length=683
Score = 80.1 bits (196), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 68/206 (33%), Positives = 100/206 (49%), Gaps = 20/206 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+LG G FG V Y G G+ +AVK L G Q S +K EI +L L H +++
Sbjct 365 NELGRGGFGSV----YKGVFSG-GQEIAVKRLSCTSG-QGDSEFKNEILLLAKLQHRNLV 418
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ------ICEGMAYL 1014
+ G C + E+ L V E++ SL +++ + QLL + + + G+ YL
Sbjct 419 RLLGFCIEGQERIL--VYEFIKNASLDNFI--FDLKKRQLLDWGVRYKMIGGVARGLLYL 474
Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWYAP 1070
H IHRDL A N+LLD + KI DFGLAK + +R + AP
Sbjct 475 HEDSRYRIIHRDLKASNILLDQEMNPKIADFGLAKLYDTDQTSTHRFTSKIAGTYGYMAP 534
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLT 1096
E +F +DV+SFGV + E++T
Sbjct 535 EYAIYGQFSVKTDVFSFGVLVIEIIT 560
Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 53/206 (26%), Positives = 88/206 (43%), Gaps = 29/206 (14%)
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
GQE+ V K L + F L++++ H +L + G C+ G E I+V E++++
Sbjct 383 GQEIAV--KRLSCTSGQGDSEFKNEILLLAKLQHRNLVRLLGFCIEGQERILVYEFIKNA 440
Query 694 PLDVWLRRERGHVPMAW----KMVVAQQLASALSYLENKN---LVHGNVCGRNILL---- 742
LD ++ + + W KM+ +A L YL + ++H ++ NILL
Sbjct 441 SLDNFIFDLKKRQLLDWGVRYKMIGG--VARGLLYLHEDSRYRIIHRDLKASNILLDQEM 498
Query 743 ----ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKW 798
A GLA KL D + ++APE G S+ T D +
Sbjct 499 NPKIADFGLA-------KLYDTDQTSTHRFTSKIAGTYGYMAPEYAIYGQFSVKT--DVF 549
Query 799 GFGATLLEICFDGEAPLQSRSPSEKE 824
FG ++EI G+ RS ++E
Sbjct 550 SFGVLVIEI-ITGKGNNNGRSNDDEE 574
>sp|Q54XX5|Y9849_DICDI Probable serine/threonine-protein kinase
DDB_G0278535 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0278535
PE=3 SV=1
Length=848
Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 78/288 (27%), Positives = 122/288 (42%), Gaps = 26/288 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G GKV Y G+ VAVK LK+ +K+E I+ ++ + ++ +
Sbjct 535 LGSGSSGKVYKGLYK------GKEVAVKVLKSITTQSQLEEFKKEFQIMGSIRSQFMVTF 588
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLH--AQH 1018
G C E L +VMEY SL + ++ IG + F Q+ G+ LH
Sbjct 589 YGAC---IEPKLCMVMEYCSRDSLYHVMNTKKYDIGWDRFFQFTMQMTLGVQCLHNWTPQ 645
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKEYK 1077
+HRD + N+L++ D K+ DFGL++ + + G F Y +PE
Sbjct 646 IVHRDFKSLNLLVNEDWECKVSDFGLSRFNTADNLETLSKIRG---TFAYCSPEVAVGNG 702
Query 1078 FYYA--SDVWSFGVTLYELLTHC-DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
Y SD++S G+ +EL+T + S P + E I +L E G R
Sbjct 703 SLYTTKSDIYSIGIVFWELVTRVINGEYSRP--YSEYSHIKMDFQIMLNSKE----GLRP 756
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182
P P + L K C E + RP+ E +I L + +Y +
Sbjct 757 TLPQNTPPGLEALYKQCVNQEQTLRPSCEEIIETLNRLRHEYMSSKTT 804
Score = 41.2 bits (95), Expect = 0.080, Method: Compositional matrix adjust.
Identities = 70/317 (22%), Positives = 112/317 (35%), Gaps = 59/317 (19%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L+ L +D E+ LG G+ VY+G L G++
Sbjct 516 LTNLEHWVIDHSELEYTLKLGSGSSGKVYKG--------------------LYKGKE--- 552
Query 636 ELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
V +KVL L F + +M + + +G C+ P+ MV EY
Sbjct 553 ---VAVKVLKSITTQSQLEEFKKEFQIMGSIRSQFMVTFYGACIE-PKLCMVMEYCSRDS 608
Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGLAEGTS 752
L + ++ + Q+ + L N +VH + N+L+
Sbjct 609 LYHVMNTKKYDIGWDRFFQFTMQMTLGVQCLHNWTPQIVHRDFKSLNLLV-------NED 661
Query 753 PFIKLSDPGVG-LGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
K+SD G+ E + +I + +PE G + +T D + G E+
Sbjct 662 WECKVSDFGLSRFNTADNLETLSKIRGTFAYCSPEVAVGNGSLYTTKSDIYSIGIVFWEL 721
Query 808 C---FDGEAPLQSRSPSEKEHFYQR-----------QHRLPEPSCPQLATLTSQCLTYEP 853
+GE SR SE H + LP+ + P L L QC+ E
Sbjct 722 VTRVINGEY---SRPYSEYSHIKMDFQIMLNSKEGLRPTLPQNTPPGLEALYKQCVNQEQ 778
Query 854 TQRPSFRTILRDLTRLQ 870
T RPS I+ L RL+
Sbjct 779 TLRPSCEEIIETLNRLR 795
>sp|Q9TZM3|LRK1_CAEEL Leucine-rich repeat serine/threonine-protein
kinase 1 OS=Caenorhabditis elegans OX=6239 GN=lrk-1 PE=1
SV=6
Length=2393
Score = 80.9 bits (198), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 98/338 (29%), Positives = 141/338 (42%), Gaps = 82/338 (24%)
Query 882 PDSPASD---PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM--VAVKALK-AD 935
PD+ +D H LK+ R LG G FG V N GE+ VA K L+ D
Sbjct 1676 PDTVFADIENALTIHPDQLKRSRMLGRGAFGFVFRATVRQPN---GELCEVAQKMLEPVD 1732
Query 936 CGPQHR-----------SGWK---------------QEIDILRTLYHEHIIKYKGCCEDQ 969
GP R WK QE+ +L + H ++I G C
Sbjct 1733 PGPGGRPSALAAYKAAADKWKRDSMEFACRAYCTSRQELSLLSRMKHPNVIGLVGVCT-- 1790
Query 970 GEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHAQHYIHRDL 1024
L LV+E PLG+L L H + L + A Q+ + YLH+ H I+RDL
Sbjct 1791 --FPLSLVVELAPLGALNQLLGSHRKAGTKLSLGVIKESAVQVARALEYLHSAHIIYRDL 1848
Query 1025 AARNVL---------LDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLK 1074
+ NVL D L+K+GD+G++++V P G +G + APE ++
Sbjct 1849 KSENVLGWRFPAPFSPQTDVLLKLGDYGISRSVLPSGGAKGFGGTEG-----FMAPEIVR 1903
Query 1075 ---EYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
E ++ D +SFG+ LYELLT +S + + L+ G VL ELL
Sbjct 1904 FNGEEEYTQKVDCFSFGMFLYELLTLKFPFESEEHVKERMLD------GARPVLLPHELL 1957
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
LP P + L+ +CW RP+ L+
Sbjct 1958 -----LPTP------MLDLLVHCWSAHPESRPSSSQLV 1984
>sp|Q8VBY2|KKCC1_MOUSE Calcium/calmodulin-dependent protein kinase
kinase 1 OS=Mus musculus OX=10090 GN=Camkk1 PE=1 SV=1
Length=505
Score = 79.7 bits (195), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 51/150 (34%), Positives = 79/150 (53%), Gaps = 6/150 (4%)
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ 1005
QEI IL+ L H +++K +D E +L LV + + G + + Q L+ +
Sbjct 198 QEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFPEEQARLYLR 257
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
I G+ YLH Q +HRD+ N+LL +D VKI DFG++ EG++ ++ +P
Sbjct 258 DIILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF-EGND-AQLSSTAGTPA 315
Query 1066 FWYAPECLKEYKFYY---ASDVWSFGVTLY 1092
F APE + + + A DVW+ GVTLY
Sbjct 316 FM-APEAISDSGQSFSGKALDVWATGVTLY 344
>sp|P52389|CDC2_VIGUN Cell division control protein 2 homolog
OS=Vigna unguiculata OX=3917 GN=CDC2 PE=2 SV=1
Length=294
Score = 77.4 bits (189), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 64/207 (31%), Positives = 101/207 (49%), Gaps = 20/207 (10%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYH 956
+K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ + H
Sbjct 5 EKVEKIGEGTYGVV----YKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR--DYLPRHSIGLAQLLLFAQQICEGMAYL 1014
+I++ + EK L LV EY+ L + D P Q+ +F QI G+AY
Sbjct 61 RNIVRLQDVV--HSEKRLYLVFEYLDLDLKKHMDSSPEFVKDPRQVKMFLYQILCGIAYC 118
Query 1015 HAQHYIHRDLAARNVLLD-NDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070
H+ +HRDL +N+L+D +K+ DFGLA+A +P + V WY AP
Sbjct 119 HSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEV------VTLWYRAP 172
Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLT 1096
E L + Y DVWS G E++
Sbjct 173 EILLGSRHYSTPVDVWSVGCLFAEMVN 199
>sp|Q6EU49|WNK4_ORYSJ Probable serine/threonine-protein kinase
WNK4 OS=Oryza sativa subsp. japonica OX=39947 GN=WNK4 PE=2
SV=1
Length=612
Score = 80.1 bits (196), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 65/216 (30%), Positives = 105/216 (49%), Gaps = 20/216 (9%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD---CGPQHRSGW 944
DPT +RY++ LG G V Y ++ G VA ++ D P +
Sbjct 19 DPT---RRYIRYNEVLGRGAMKTV----YKAFDEVEGIEVAWSQVEIDEVMQSPDNLERL 71
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLF 1003
E+ +L++L HE+++K+ D +K++ ++ E GSLR Y +H + L + +
Sbjct 72 YSEVHLLKSLKHENVMKFYNYWVDDQKKTINVITELFTSGSLRQYRQKHPRVDLKAIKNW 131
Query 1004 AQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
A+Q+ G+ YLH IHRDL N+ ++ N VKIGD GLA + R +
Sbjct 132 ARQVLRGLDYLHTHQPPIIHRDLKCDNIFVNGNHGEVKIGDLGLATVMLTP----RAKSV 187
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+P F APE E + D++SFG+ + E+ T
Sbjct 188 IGTPEFM-APELYDE-NYDELVDIYSFGMCMLEMFT 221
>sp|Q9DGA2|CDK1_ORYJA Cyclin-dependent kinase 1 OS=Oryzias javanicus
OX=123683 GN=cdk1 PE=2 SV=1
Length=303
Score = 77.4 bits (189), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 66/215 (31%), Positives = 109/215 (51%), Gaps = 25/215 (12%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957
KI +GEG +G V Y + TG++VA+K ++ + + S +E+ +L+ L H
Sbjct 6 KIEKIGEGTYGVV----YKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLL--FAQQICEGMAY 1013
++++ E L L+ E++ + L+ YL G + +L+ + QI EG+ +
Sbjct 62 NVVRLLDVL--MQESRLYLIFEFLSM-DLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWYAPE 1071
H + +HRDL +N+L+DN ++K+ DFGLA+A VP RV +++ APE
Sbjct 119 CHRRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVP-----VRVYTHEVVTLWYRAPE 173
Query 1072 C-LKEYKFYYASDVWSFGVTLYELLT-----HCDS 1100
L ++ DVWS G EL T H DS
Sbjct 174 VLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDS 208
>sp|O49717|CDPKF_ARATH Calcium-dependent protein kinase 15 OS=Arabidopsis
thaliana OX=3702 GN=CPK15 PE=2 SV=1
Length=554
Score = 79.7 bits (195), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 83/296 (28%), Positives = 132/296 (45%), Gaps = 34/296 (11%)
Query 815 LQSRSPSEK-EHFYQRQHRLPE-PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
+QS P+ + E+ R P+ P PQ+ T T ++ +P + I + QP
Sbjct 20 VQSSIPTNQPENHVSRDVLKPQKPPSPQIPTTTQSNHHHQQESKPVNQQIEKKHVLTQP- 78
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932
L ++ ++ P ++ ++LG G FG Y + TG A K++
Sbjct 79 -LKPIVFRETETILGKPFEEIRKLYTLGKELGRGQFG----ITYTCKENSTGNTYACKSI 133
Query 933 --KADCGPQHRSGWKQEIDILRTLY-HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD- 988
+ Q K+EI I++ L E+I++ KG ED+ +S+ LVME L D
Sbjct 134 LKRKLTRKQDIDDVKREIQIMQYLSGQENIVEIKGAYEDR--QSIHLVMELCGGSELFDR 191
Query 989 ------YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKI 1039
Y + + G+ + +L QIC H IHRDL N LL D + ++K
Sbjct 192 IIAQGHYSEKAAAGVIRSVLNVVQIC------HFMGVIHRDLKPENFLLASTDENAMLKA 245
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
DFGL+ + EG +V D ++ APE L+ + D+WS G+ LY LL
Sbjct 246 TDFGLSVFIEEG----KVYRDIVGSAYYVAPEVLRR-SYGKEIDIWSAGIILYILL 296
>sp|Q8GUQ5|BRI1_SOLLC Brassinosteroid LRR receptor kinase OS=Solanum
lycopersicum OX=4081 GN=CURL3 PE=1 SV=1
Length=1207
Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 76/251 (30%), Positives = 118/251 (47%), Gaps = 26/251 (10%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
FH L +G G FG V G +VA+K L G R + E++ +
Sbjct 888 FHNDSL-----VGSGGFGDVY-----KAQLKDGSVVAIKKLIHVSGQGDRE-FTAEMETI 936
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQIC-- 1008
+ H +++ G C+ GE+ L LV EY+ GSL D L R IG+ ++I
Sbjct 937 GKIKHRNLVPLLGYCK-VGEERL-LVYEYMKYGSLEDVLHDRKKIGIKLNWPARRKIAIG 994
Query 1009 --EGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
G+A+LH H IHRD+ + NVLLD + ++ DFG+A+ + + V +
Sbjct 995 AARGLAFLHHNCIPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGT 1054
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI----AQGQM 1119
P + PE + ++ DV+S+GV L ELLT + S L+G A+G++
Sbjct 1055 PG-YVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFGDNNLVGWVKLHAKGKI 1113
Query 1120 TVLRLTELLER 1130
T + ELL+
Sbjct 1114 TDVFDRELLKE 1124
Score = 36.6 bits (83), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 24/94 (26%), Positives = 49/94 (52%), Gaps = 6/94 (6%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAW--K 711
F + ++ H +L + G C G E ++V EY+++G L DV R++ + + W +
Sbjct 929 FTAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKYGSLEDVLHDRKKIGIKLNWPAR 988
Query 712 MVVAQQLASALSYLENK---NLVHGNVCGRNILL 742
+A A L++L + +++H ++ N+LL
Sbjct 989 RKIAIGAARGLAFLHHNCIPHIIHRDMKSSNVLL 1022
>sp|Q02723|RKIN1_SECCE Carbon catabolite-derepressing protein
kinase OS=Secale cereale OX=4550 GN=RKIN1 PE=2 SV=1
Length=502
Score = 79.7 bits (195), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 73/208 (35%), Positives = 97/208 (47%), Gaps = 21/208 (10%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILR- 952
YL KI LG G F KV + + T VA+K L + P+ K+EI ILR
Sbjct 15 YLGKI--LGVGTFAKVII----AEHKHTRHKVAIKVLNRRQMRAPEMEEKAKREIKILRL 68
Query 953 --TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICE 1009
L H HII+ K + +VMEY G L DY L + + + QQI
Sbjct 69 FIDLIHPHIIRVYEVI--VTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQIIS 126
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ Y H +HRDL N+LLD+ VK+ DFGL+ + +GH + + + A
Sbjct 127 AVEYCHRNKVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGH----FLKTSCGSLNYAA 182
Query 1070 PECLKEYKFYYAS--DVWSFGVTLYELL 1095
PE + K Y DVWS GV LY LL
Sbjct 183 PEVISG-KLYAGPEIDVWSCGVILYALL 209
Score = 38.9 bits (89), Expect = 0.32, Method: Compositional matrix adjust.
Identities = 55/238 (23%), Positives = 96/238 (40%), Gaps = 26/238 (11%)
Query 638 RVVLKVLD------PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+V +KVL+ P + A + L + H H+ V+ V V + +V EY +
Sbjct 39 KVAIKVLNRRQMRAPEMEEKAKREIKILRLFIDLIHPHIIRVYEVIVTPKDIFVVMEYCQ 98
Query 692 HGPL-DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
+G L D L + R A + QQ+ SA+ Y +VH ++ N+LL
Sbjct 99 NGDLLDYILEKRRLQEDEARRTF--QQIISAVEYCHRNKVVHRDLKPENLLL-------D 149
Query 751 TSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ +KL+D GL + + + + + APE + G + +D W G L
Sbjct 150 SKYNVKLAD--FGLSNVMHDGHFLKTSCGSLNYAAPEVISGKLYA-GPEIDVWSCGVILY 206
Query 806 EICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
+ G P + P+ + + LP + L S+ L +P +R + I
Sbjct 207 AL-LCGAVPFDDDNIPNLFKKIKGGTYILPIYLSDLVRDLISRMLIVDPMKRITIGEI 263
>sp|Q7Z8E9|STE20_PYRO7 Serine/threonine-protein kinase MST20 OS=Pyricularia
oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
OX=242507 GN=MST20 PE=3 SV=3
Length=914
Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 53/208 (25%), Positives = 100/208 (48%), Gaps = 14/208 (7%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DP ++ + K +G+G G V Y G+ +VA+K + + P+ + E
Sbjct 629 DPREIYRSFTK----IGQGASGGV----YTGHERGSNRLVAIKQMNLEQQPK-KDLIINE 679
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +++ H +I+ + GE L +VME++ GSL D + + + Q+ ++
Sbjct 680 ILVMKDSSHPNIVNFIDSYLCGGE--LWVVMEFMEGGSLTDVVTFNIMTEGQIASVCRET 737
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
G+ +LH++ IHRD+ + N+LL + +K+ DFG + +E R +W
Sbjct 738 LLGLQHLHSKGVIHRDIKSDNILLSMEGNIKLTDFGFCATI---NEAQNKRTTMVGTPYW 794
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095
APE + ++ D+WS G+ E++
Sbjct 795 MAPEVVTRKEYGRKVDIWSLGIMAIEMI 822
Score = 41.6 bits (96), Expect = 0.057, Method: Compositional matrix adjust.
Identities = 50/205 (24%), Positives = 83/205 (40%), Gaps = 36/205 (18%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G +RG V +K ++ +M SH ++ + G E +V E+
Sbjct 651 GHERGSNRLVAIKQMNLEQQPKKDLIINEILVMKDSSHPNIVNFIDSYLCGGELWVVMEF 710
Query 690 VEHGPL-DVWLRRERGHVPMAWKMVVAQQLAS-------ALSYLENKNLVHGNVCGRNIL 741
+E G L DV + + ++ Q+AS L +L +K ++H ++ NIL
Sbjct 711 MEGGSLTDV----------VTFNIMTEGQIASVCRETLLGLQHLHSKGVIHRDIKSDNIL 760
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAM 795
L+ G IKL+D G A E + +R W+APE + +
Sbjct 761 LSMEG-------NIKLTD--FGFCATINEAQNKRTTMVGTPYWMAPEVV--TRKEYGRKV 809
Query 796 DKWGFGATLLEICFDGEAPLQSRSP 820
D W G +E+ +GE P + SP
Sbjct 810 DIWSLGIMAIEM-IEGEPPYLTESP 833
>sp|Q9LX29|ACR4L_ARATH Serine/threonine-protein kinase-like protein
ACR4 OS=Arabidopsis thaliana OX=3702 GN=ACR4 PE=1 SV=1
Length=895
Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 75/250 (30%), Positives = 114/250 (46%), Gaps = 41/250 (16%)
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
DL LQ A V T A+D K+ +G+G F S DGT
Sbjct 487 DLDELQKRRRARVFTYEELEKAADG-------FKEESIVGKGSF---SCVYKGVLRDGT- 535
Query 925 EMVAVK-ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
VAVK A+ + ++ + ++ E+D+L L H H++ G CE+ GE+ LV E++
Sbjct 536 -TVAVKRAIMSSDKQKNSNEFRTELDLLSRLNHAHLLSLLGYCEECGER--LLVYEFMAH 592
Query 984 GSLRDYLPRHSIGLAQLL------LFAQQICEGMAYLHAQH---YIHRDLAARNVLLDND 1034
GSL ++L + L + L A Q G+ YLH IHRD+ + N+L+D +
Sbjct 593 GSLHNHLHGKNKALKEQLDWVKRVTIAVQAARGIEYLHGYACPPVIHRDIKSSNILIDEE 652
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF--------WYAPECLKEYKFYYASDVWS 1086
++ DFGL+ P D SP+ + PE + + SDV+S
Sbjct 653 HNARVADFGLSLLGP---------VDSGSPLAELPAGTLGYLDPEYYRLHYLTTKSDVYS 703
Query 1087 FGVTLYELLT 1096
FGV L E+L+
Sbjct 704 FGVLLLEILS 713
Score = 43.5 bits (101), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 53/222 (24%), Positives = 90/222 (41%), Gaps = 33/222 (15%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
S +G+G+ + VY+G LR G + V ++ +
Sbjct 516 SIVGKGSFSCVYKGVLR-----------------------DGTTVAVKRAIMSSDKQKNS 552
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP--MAW 710
F L+S+++H HL + G C E ++V E++ HG L L + + + W
Sbjct 553 NEFRTELDLLSRLNHAHLLSLLGYCEECGERLLVYEFMAHGSLHNHLHGKNKALKEQLDW 612
Query 711 --KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
++ +A Q A + YL ++H ++ NIL+ A + L P V G
Sbjct 613 VKRVTIAVQAARGIEYLHGYACPPVIHRDIKSSNILIDEEHNARVADFGLSLLGP-VDSG 671
Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+ E + +L PE + L+T D + FG LLEI
Sbjct 672 SPLAELPAGTLGYLDPEYYR--LHYLTTKSDVYSFGVLLLEI 711
>sp|P97756|KKCC1_RAT Calcium/calmodulin-dependent protein kinase
kinase 1 OS=Rattus norvegicus OX=10116 GN=Camkk1 PE=1 SV=1
Length=505
Score = 79.7 bits (195), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 51/150 (34%), Positives = 79/150 (53%), Gaps = 6/150 (4%)
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ 1005
QEI IL+ L H +++K +D E +L LV + + G + + Q L+ +
Sbjct 198 QEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFPEEQARLYLR 257
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
I G+ YLH Q +HRD+ N+LL +D VKI DFG++ EG++ ++ +P
Sbjct 258 DIILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF-EGND-AQLSSTAGTPA 315
Query 1066 FWYAPECLKEYKFYY---ASDVWSFGVTLY 1092
F APE + + + A DVW+ GVTLY
Sbjct 316 FM-APEAISDTGQSFSGKALDVWATGVTLY 344
>sp|O64784|Y1136_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61360 OS=Arabidopsis thaliana OX=3702
GN=At1g61360 PE=2 SV=1
Length=821
Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 65/204 (32%), Positives = 96/204 (47%), Gaps = 16/204 (8%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LG+G FG V G+ +AVK L + Q + EI ++ L H ++
Sbjct 501 LNKLGQGGFGTVY-----KGKLQDGKEIAVKRLTSS-SVQGTEEFMNEIKLISKLQHRNL 554
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLR----DYLPRHSIGLAQLLLFAQQICEGMAYLH 1015
++ GCC D GE+ L LV EY+ SL D + I A Q I G+ YLH
Sbjct 555 LRLLGCCID-GEEKL-LVYEYMVNKSLDIFIFDLKKKLEIDWATRFNIIQGIARGLLYLH 612
Query 1016 AQHY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+ +HRDL N+LLD KI DFGLA+ G+++ + + +PE
Sbjct 613 RDSFLRVVHRDLKVSNILLDEKMNPKISDFGLARLF-HGNQHQDSTGSVVGTLGYMSPEY 671
Query 1073 LKEYKFYYASDVWSFGVTLYELLT 1096
F SD++SFGV + E++T
Sbjct 672 AWTGTFSEKSDIYSFGVLMLEIIT 695
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 59/244 (24%), Positives = 105/244 (43%), Gaps = 43/244 (18%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
LN ++ + + L+ LGQG VY+G+L ++GK
Sbjct 483 LNFFEIHDLQTATNNFSVLNKLGQGGFGTVYKGKL--------QDGK------------- 521
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ +K L S F L+S++ H +L + G C+ G E ++V EY+ +
Sbjct 522 ----EIAVKRLTSSSVQGTEEFMNEIKLISKLQHRNLLRLLGCCIDGEEKLLVYEYMVNK 577
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
LD+++ + + + W + + Q +A L YL + + V R++ ++ + L E
Sbjct 578 SLDIFIFDLKKKLEIDWATRFNIIQGIARGLLYLHRDSFLR--VVHRDLKVSNILLDEKM 635
Query 752 SPFIKLSDPGVGLGAL--------SREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+P K+SD GL L S V + +++PE G + S D + FG
Sbjct 636 NP--KISD--FGLARLFHGNQHQDSTGSVVGTLGYMSPEYAWTG--TFSEKSDIYSFGVL 689
Query 804 LLEI 807
+LEI
Sbjct 690 MLEI 693
>sp|Q9LJF3|BRL3_ARATH Receptor-like protein kinase BRI1-like 3
OS=Arabidopsis thaliana OX=3702 GN=BRL3 PE=1 SV=1
Length=1164
Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 82/285 (29%), Positives = 126/285 (44%), Gaps = 32/285 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V G +VA+K L G R + E++ + + H +++
Sbjct 864 IGSGGFGDVY-----KAKLADGSVVAIKKLIQVTGQGDRE-FMAEMETIGKIKHRNLVPL 917
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL------LFAQQICEGMAYLHA 1016
G C+ GE+ L LV EY+ GSL L + L A G+A+LH
Sbjct 918 LGYCK-IGEERL-LVYEYMKYGSLETVLHEKTKKGGIFLDWSARKKIAIGAARGLAFLHH 975
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
H IHRD+ + NVLLD D + ++ DFG+A+ V + V +P + PE
Sbjct 976 SCIPHIIHRDMKSSNVLLDQDFVARVSDFGMARLVSALDTHLSVSTLAGTP-GYVPPEYY 1034
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLE---LIGIAQGQMTVLRLTELL 1128
+ ++ DV+S+GV L ELL S + P P +F E L+G A+ R E+L
Sbjct 1035 QSFRCTAKGDVYSYGVILLELL----SGKKPIDPEEFGEDNNLVGWAKQLYREKRGAEIL 1090
Query 1129 ERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170
+ L E+ H +K C + RPT ++ + K
Sbjct 1091 D--PELVTDKSGDVELLHYLKIASQCLDDRPFKRPTMIQVMTMFK 1133
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 58/260 (22%), Positives = 110/260 (42%), Gaps = 57/260 (22%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL--RRERGHVPMAW-- 710
F + ++ H +L + G C G E ++V EY+++G L+ L + ++G + + W
Sbjct 899 FMAEMETIGKIKHRNLVPLLGYCKIGEERLLVYEYMKYGSLETVLHEKTKKGGIFLDWSA 958
Query 711 KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LG 765
+ +A A L++L + +++H ++ N+LL + +A ++SD G+ +
Sbjct 959 RKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDQDFVA-------RVSDFGMARLVS 1011
Query 766 ALSREERVERIP----WLAPE------CLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
AL V + ++ PE C G D + +G LLE+ G+ P+
Sbjct 1012 ALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKG--------DVYSYGVILLEL-LSGKKPI 1062
Query 816 QSRSPSEKEHFY------QRQHRLPEPSCPQLAT-------------LTSQCLTYEPTQR 856
E + R+ R E P+L T + SQCL P +R
Sbjct 1063 DPEEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELLHYLKIASQCLDDRPFKR 1122
Query 857 PSF---RTILRDLTRLQPHN 873
P+ T+ ++L ++ N
Sbjct 1123 PTMIQVMTMFKELVQVDTEN 1142
>sp|F4ICB6|IBS1_ARATH Protein IMPAIRED IN BABA-INDUCED STERILITY
1 OS=Arabidopsis thaliana OX=3702 GN=IBS1 PE=3 SV=1
Length=709
Score = 80.1 bits (196), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 63/209 (30%), Positives = 98/209 (47%), Gaps = 12/209 (6%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDI 950
F +K+ +G+G + V + TG +VA+K ++ D P+ +EI I
Sbjct 126 FRSDAFEKLEKIGQGTYSSV----FRARETETGRIVALKKVRFDNFEPESVRFMAREILI 181
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQIC 1008
LR L H +IIK +G + S+ LV EY+ L L I Q+ + +Q+
Sbjct 182 LRKLNHPNIIKLEGIVTSKLSCSIHLVFEYME-HDLTGLLSSPDIDFTTPQIKCYMKQLL 240
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
G+ + HA+ +HRD+ N+L++N+ ++K+ DFGLA + WY
Sbjct 241 SGLDHCHARGVMHRDIKGSNLLVNNEGILKVADFGLANFCNASGNKQPL--TSRVVTLWY 298
Query 1069 A-PECLKEYKFYYAS-DVWSFGVTLYELL 1095
PE L Y AS D+WS G ELL
Sbjct 299 RPPELLLGATEYGASVDLWSVGCVFAELL 327
>sp|P87253|KPC1_NEUCR Protein kinase C-like OS=Neurospora crassa
(strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
FGSC 987) OX=367110 GN=NCU06544 PE=3 SV=2
Length=1142
Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 90/198 (45%), Gaps = 14/198 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957
LG+G+FGKV L + ++ A+K LK + ++ K+ I H
Sbjct 823 LGKGNFGKVML----AETKKSRKLYAIKVLKKEFIIENDEVESIRSEKRVFLIANRERHP 878
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ C Q E + VMEY+ G L ++ R G + +A ++C + Y H
Sbjct 879 FLTNLHACF--QTETRVYFVMEYISGGDLMLHIQRGMFGTKRAQFYAAEVCLALKYFHEN 936
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
I+RDL N+LL D +KI D+GL K E Y + APE L + K
Sbjct 937 GVIYRDLKLDNILLTLDGHIKIADYGLCK---EDMWYGSTTSTFCGTPEFMAPEILLDKK 993
Query 1078 FYYASDVWSFGVTLYELL 1095
+ A D W+FGV +Y++L
Sbjct 994 YGRAVDWWAFGVLIYQML 1011
>sp|Q8SQW2|CTK1_ENCCU Probable CTD kinase subunit alpha homolog
OS=Encephalitozoon cuniculi (strain GB-M1) OX=284813 GN=CTK1
PE=3 SV=1
Length=329
Score = 77.8 bits (190), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 67/245 (27%), Positives = 111/245 (45%), Gaps = 22/245 (9%)
Query 885 PASDPTVF-HKRY------LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
PA + + H+R+ +KIR +GEG FG+V L G K K G
Sbjct 3 PAEEGEILAHRRFTATKMEYEKIRIIGEGTFGQVIL-----ARKGRARYALKKVSKEKEG 57
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL 997
+ +E+ +LR + H I++ + G + +V Y P L ++ + +
Sbjct 58 LSVTT--IREVQVLRAMGHPSIVRLIEVVVEPG-GDIYMVFPYFPY-DLNRFIRSNKMTC 113
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+++ QI +G+ Y+H++ +HRDL + N+LLD I DFG+A+ + Y
Sbjct 114 SEIKHIFYQIAQGVCYIHSKGIMHRDLKSANILLDQKLNASIADFGMARYTTKTGAY--- 170
Query 1058 REDGDSPVFWYAPEC-LKEYKFYYASDVWSFGVTLYEL-LTHCDSSQSPPTKFLELIGIA 1115
G +++ APE L + YA D+WS G L E+ L H S LE++ A
Sbjct 171 -TPGMVTLWYRAPEILLGSSSYTYAVDIWSLGCILTEMYLGHMIFQGSTEMLQLEMVIHA 229
Query 1116 QGQMT 1120
G +
Sbjct 230 CGSIN 234
>sp|P10666|KS6AB_XENLA Ribosomal protein S6 kinase 2 beta OS=Xenopus
laevis OX=8355 PE=2 SV=1
Length=629
Score = 79.7 bits (195), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 57/199 (29%), Positives = 104/199 (52%), Gaps = 8/199 (4%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEH 958
++ LG+G FGKV L T ++ A+K LK A + R K E DIL ++H
Sbjct 65 LKVLGQGSFGKVFL-VRKITPPDANQLYAMKVLKKATLKVRDRVRTKMERDILADVHHPF 123
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ-LLLFAQQICEGMAYLHAQ 1017
+++ + +G+ L L+++++ G L L + + + + + ++ G+ +LH+
Sbjct 124 VVRLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSL 181
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
I+RDL N+LLD + +K+ DFGL+K E ++ + V + APE +
Sbjct 182 GIIYRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKKAYSFCGTVEYMAPEVVNRQG 238
Query 1078 FYYASDVWSFGVTLYELLT 1096
+ +D WS+GV ++E+LT
Sbjct 239 HSHGADWWSYGVLMFEMLT 257
Score = 61.2 bits (147), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 59/194 (30%), Positives = 91/194 (47%), Gaps = 30/194 (15%)
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKS 973
C + GT AVK + + + +EI+ILR H +II K E+ S
Sbjct 430 CKRCVHKGTNMEYAVKVID-----KSKRDPSEEIEILRRYGQHPNIITLKDVYEECN--S 482
Query 974 LQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030
+ LV E + G L D + R S A +LF +C+ + YLH+Q +HRDL N+L
Sbjct 483 IYLVTELMRGGELLDRILRQKFFSEREACSVLFT--VCKTVEYLHSQGVVHRDLKPSNIL 540
Query 1031 LDND----RLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVF---WYAPECLKEYKFYYA 1081
++ ++I DFG +K + E+G +P + + APE LK +
Sbjct 541 YVDESGDPESIRICDFGFSKQLRA--------ENGLLMTPCYTANFVAPEVLKRQGYDEG 592
Query 1082 SDVWSFGVTLYELL 1095
D+WS G+ LY +L
Sbjct 593 CDIWSLGILLYTML 606
>sp|O81069|Y2899_ARATH Probable leucine-rich repeat receptor-like
protein kinase At2g28990 OS=Arabidopsis thaliana OX=3702
GN=At2g28990 PE=1 SV=1
Length=884
Score = 80.1 bits (196), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 62/204 (30%), Positives = 98/204 (48%), Gaps = 16/204 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+ LGEG FG V + E VAVK L + Q +K E+++L ++H +++
Sbjct 581 KALGEGGFGVVYHGFVNVI-----EQVAVKLL-SQSSSQGYKHFKAEVELLMRVHHINLV 634
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA----QLLLFAQQICEGMAYLHA 1016
G C D+GE L L+ EY+P G L+ +L G L G+ YLH
Sbjct 635 SLVGYC-DEGEH-LALIYEYMPNGDLKQHLSGKHGGFVLSWESRLKIVLDAALGLEYLHT 692
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+HRD+ N+LLD K+ DFGL+++ P G+E +P + PE
Sbjct 693 GCVPPMVHRDIKTTNILLDQHLQAKLADFGLSRSFPIGNEKNVSTVVAGTPGYL-DPEYY 751
Query 1074 KEYKFYYASDVWSFGVTLYELLTH 1097
+ SD++SFG+ L E++++
Sbjct 752 QTNWLTEKSDIYSFGIVLLEIISN 775
Score = 45.8 bits (107), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 54/202 (27%), Positives = 85/202 (42%), Gaps = 23/202 (11%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K+L S F L+ +V H +L + G C G ++ EY+ +G L
Sbjct 601 QVAVKLLSQSSSQGYKHFKAEVELLMRVHHINLVSLVGYCDEGEHLALIYEYMPNGDLKQ 660
Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752
L + G ++W ++ + A L YL +VH ++ NILL + A
Sbjct 661 HLSGKHGGFVLSWESRLKIVLDAALGLEYLHTGCVPPMVHRDIKTTNILLDQHLQA---- 716
Query 753 PFIKLSDPGVGLG-ALSREERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATLLE 806
KL+D G+ + E+ V + +L PE N L+ D + FG LLE
Sbjct 717 ---KLADFGLSRSFPIGNEKNVSTVVAGTPGYLDPEYYQ--TNWLTEKSDIYSFGIVLLE 771
Query 807 ICFDGEAPLQSRSPSEKEHFYQ 828
I + QSR EK H +
Sbjct 772 IISNRPIIQQSR---EKPHIVE 790
>sp|Q2NL51|GSK3A_MOUSE Glycogen synthase kinase-3 alpha OS=Mus
musculus OX=10090 GN=Gsk3a PE=1 SV=2
Length=490
Score = 79.3 bits (194), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 71/212 (33%), Positives = 104/212 (49%), Gaps = 35/212 (17%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I+ +G G FG V Y T E+VA+K + D ++R E+ I+R L H +I
Sbjct 122 IKVIGNGSFGVV----YQARLAETRELVAIKKVLQDKRFKNR-----ELQIMRKLDHCNI 172
Query 960 IKYKGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRHSIGLAQLL-------LFAQQIC 1008
++ + GEK L LV+EYVP R + RH A+L+ ++ Q+
Sbjct 173 VRLRYFFYSSGEKKDELYLNLVLEYVPETVYR--VARH-FTKAKLITPIIYIKVYMYQLF 229
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGH---EYYRVREDGDSP 1064
+AY+H+Q HRD+ +N+L+D D V K+ DFG AK + G Y R
Sbjct 230 RSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR------ 283
Query 1065 VFWYAPECLKEYKFYYAS-DVWSFGVTLYELL 1095
++ APE + Y +S DVWS G L ELL
Sbjct 284 -YYRAPELIFGATDYTSSIDVWSAGCVLAELL 314
Score = 35.0 bits (79), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 31/128 (24%), Positives = 58/128 (45%), Gaps = 12/128 (9%)
Query 685 MVTEYVEHGPLDVW--LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+V EYV V + + P+ + V QL +L+Y+ ++ + H ++ +N+L+
Sbjct 193 LVLEYVPETVYRVARHFTKAKLITPIIYIKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLV 252
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWG 799
+ + +KL D G + E V I + APE + GA ++++D W
Sbjct 253 ------DPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELI-FGATDYTSSIDVWS 305
Query 800 FGATLLEI 807
G L E+
Sbjct 306 AGCVLAEL 313
>sp|P34117|CDK5_DICDI Cyclin-dependent kinase 5 homolog OS=Dictyostelium
discoideum OX=44689 GN=cdk5 PE=2 SV=2
Length=292
Score = 77.0 bits (188), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 63/201 (31%), Positives = 96/201 (48%), Gaps = 16/201 (8%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK-QEIDILRTLYHE 957
KI LGEG +G V Y N TGE+VA+K ++ D + +EI +L+ L H
Sbjct 6 KIEKLGEGTYGIV----YKAKNRETGEIVALKRIRLDSEDEGVPCTAIREISLLKELKHP 61
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+I++ E+ L LV EY+ L+ YL I + F Q+ +G+A+ H
Sbjct 62 NIVRLHDVI--HTERKLTLVFEYLD-QDLKKYLDECGGEISKPTIKSFMYQLLKGVAFCH 118
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074
+HRDL +N+L++ +K+ DFGLA+A Y + WY AP+ L
Sbjct 119 DHRVLHRDLKPQNLLINRKGELKLADFGLARAFGIPVRTY----SHEVVTLWYRAPDVLM 174
Query 1075 -EYKFYYASDVWSFGVTLYEL 1094
K+ D+WS G E+
Sbjct 175 GSRKYSTPIDIWSAGCIFAEM 195
Score = 38.9 bits (89), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 49/224 (22%), Positives = 92/224 (41%), Gaps = 37/224 (17%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDP-EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+++ LG+GT VY+ + R G + ++D ED VP
Sbjct 5 SKIEKLGEGTYGIVYKAKNRETGEIVALKRIRLDSEDEGVP------------------- 45
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
A E SL+ ++ H ++ +H V + +V EY++ L +L G +
Sbjct 46 ---CTAIREI-SLLKELKHPNIVRLHDVIHTERKLTLVFEYLDQD-LKKYLDECGGEISK 100
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GL 764
QL +++ + ++H ++ +N+L+ R G +KL+D G+ G+
Sbjct 101 PTIKSFMYQLLKGVAFCHDHRVLHRDLKPQNLLINRKGE-------LKLADFGLARAFGI 153
Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ V + + AP+ L G+ ST +D W G E+
Sbjct 154 PVRTYSHEVVTLWYRAPDVL-MGSRKYSTPIDIWSAGCIFAEMA 196
>sp|P50526|SSP1_SCHPO Serine/threonine-protein kinase ssp1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=ssp1 PE=1 SV=1
Length=652
Score = 79.7 bits (195), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 64/221 (29%), Positives = 107/221 (48%), Gaps = 36/221 (16%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL----------KADCGPQHRSGWKQEID 949
I++LG G GKV L + T E++A+K + +A+ Q + ++EI
Sbjct 138 IKELGRGMHGKVKL----GRDTVTRELLAIKIIPKTERRPKLGRANASSQ-KEKVRREIA 192
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR-DYLPRHSIGLAQLLLFAQQIC 1008
IL+ H ++++ + +D + LV+EY+ G + + +++ + + +
Sbjct 193 ILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQYFRDVV 252
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD------ 1062
G+ YLH Q IHRD+ N+LL++ VKI DFG++ G + ED D
Sbjct 253 LGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAG-----LNEDNDVELAKT 307
Query 1063 --SPVFWYAPE-CLKEY-----KFYYASDVWSFGVTLYELL 1095
+P F +APE C + K A DVW+ GVTL+ LL
Sbjct 308 VGTPAF-FAPELCWTDLDRPRPKISEAIDVWALGVTLFCLL 347
Score = 35.0 bits (79), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 44/154 (29%), Positives = 64/154 (42%), Gaps = 28/154 (18%)
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA---LSREERVERIP 777
L YL + ++H ++ N+LL +S +K+SD GV A L+ + VE
Sbjct 254 GLEYLHYQGIIHRDIKPANLLL-------NSSNCVKISDFGVSYIANAGLNEDNDVELAK 306
Query 778 ------WLAPEC----LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
+ APE L +S A+D W G TL + F G P + E E F
Sbjct 307 TVGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLF-GRCPFN--ASMEYELFD 363
Query 828 Q-RQHRLPEPSCPQLA----TLTSQCLTYEPTQR 856
+ RL PS P + L + L +P QR
Sbjct 364 KIVNERLNIPSTPDIGEEGRDLLKRLLCKDPEQR 397
>sp|P51817|PRKX_HUMAN cAMP-dependent protein kinase catalytic
subunit PRKX OS=Homo sapiens OX=9606 GN=PRKX PE=1 SV=1
Length=358
Score = 78.2 bits (191), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 63/228 (28%), Positives = 107/228 (47%), Gaps = 21/228 (9%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
A L +P++ + +P V+ + + +G G FG+V L + T + ALK
Sbjct 27 APALCPSPEALSPEPPVYSLQDFDTLATVGTGTFGRVHL-----VKEKTAKHFF--ALKV 79
Query 935 DCGP-----QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
P + E +L+ + H +I+ D E+ L ++MEYVP G L Y
Sbjct 80 MSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHD--ERFLYMLMEYVPGGELFSY 137
Query 990 L-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
L R L ++ +I + YLH++ ++RDL N+LLD D +K+ DFG AK +
Sbjct 138 LRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKL 197
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+ R +P + APE ++ A D W+ G+ ++E+L+
Sbjct 198 VD-----RTWTLCGTPEY-LAPEVIQSKGHGRAVDWWALGILIFEMLS 239
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 45/162 (28%), Positives = 71/162 (44%), Gaps = 12/162 (7%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S++ +VSH L + M+ EYV G L +LR RG + + ++
Sbjct 99 SVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRN-RGRFSSTTGLFYSAEII 157
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-W 778
A+ YL +K +V+ ++ NILL R G IKL+D G + R + P +
Sbjct 158 CAIEYLHSKEIVYRDLKPENILLDRDG-------HIKLTDFGFAKKLVDRTWTLCGTPEY 210
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
LAPE + + A+D W G + E+ G P +P
Sbjct 211 LAPEVIQSKGH--GRAVDWWALGILIFEM-LSGFPPFFDDNP 249
>sp|Q5YJC2|GSK3B_SPECI Glycogen synthase kinase-3 beta OS=Spermophilus
citellus OX=9997 GN=GSK3B PE=2 SV=1
Length=420
Score = 79.0 bits (193), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 70/208 (34%), Positives = 100/208 (48%), Gaps = 33/208 (16%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V Y +GE+VA+K + D ++R E+ I+R L H +I++
Sbjct 62 IGNGSFGVV----YQAKLCDSGELVAIKKVLQDKRFKNR-----ELQIMRKLDHCNIVRL 112
Query 963 KGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRHSIGLAQLL------LFAQQICEGMA 1012
+ GEK L LV++YVP R + RH Q L L+ Q+ +A
Sbjct 113 RYFFYSSGEKKDVVYLNLVLDYVPETVYR--VARHYSRAKQTLPVIYVKLYMYQLFRSLA 170
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGH---EYYRVREDGDSPVFWY 1068
Y+H+ HRD+ +N+LLD D V K+ DFG AK + G Y R ++
Sbjct 171 YIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR-------YYR 223
Query 1069 APECLKEYKFYYAS-DVWSFGVTLYELL 1095
APE + Y +S DVWS G L ELL
Sbjct 224 APELIFGATDYTSSIDVWSAGCVLAELL 251
Score = 35.4 bits (80), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 27/110 (25%), Positives = 52/110 (47%), Gaps = 10/110 (9%)
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
R + +P+ + + QL +L+Y+ + + H ++ +N+LL + + +KL D
Sbjct 148 RAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLL------DPDTAVLKLCDF 201
Query 761 GVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
G + E V I + APE + GA ++++D W G L E+
Sbjct 202 GSAKQLVRGEPNVSYICSRYYRAPELI-FGATDYTSSIDVWSAGCVLAEL 250
>sp|Q9FZB8|Y5181_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g51810 OS=Arabidopsis thaliana OX=3702
GN=At1g51810 PE=1 SV=1
Length=871
Score = 80.1 bits (196), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 71/236 (30%), Positives = 116/236 (49%), Gaps = 33/236 (14%)
Query 883 DSPASDPTVFHKRYLKKI-------------RDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
DS +S+PT+ K KK + LG+G FG V Y + +GT E VAV
Sbjct 552 DSRSSEPTIVTKN--KKFTYAEVLTMTNNFQKILGKGGFGIV----YYGSVNGT-EQVAV 604
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K L ++ +K E+++L ++H++++ G CE +G+K L L+ EY+ G L ++
Sbjct 605 KMLSHSSAQGYKQ-FKAEVELLLRVHHKNLVGLVGYCE-EGDK-LALIYEYMANGDLDEH 661
Query 990 LPRHSIG----LAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDF 1042
+ G L A + +G+ YLH +HRD+ N+LL+ K+ DF
Sbjct 662 MSGKRGGSILNWGTRLKIALEAAQGLEYLHNGCKPLMVHRDVKTTNILLNEHFDTKLADF 721
Query 1043 GLAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
GL+++ P EG + G + + PE + SDV+SFGV L ++T+
Sbjct 722 GLSRSFPIEGETHVSTVVAG--TIGYLDPEYYRTNWLTEKSDVYSFGVVLLVMITN 775
Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 60/213 (28%), Positives = 89/213 (42%), Gaps = 34/213 (16%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
G G E +V +K+L S F L+ +V H +L + G C G + ++ EY
Sbjct 594 GSVNGTE-QVAVKMLSHSSAQGYKQFKAEVELLLRVHHKNLVGLVGYCEEGDKLALIYEY 652
Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLAR 744
+ +G LD + +RG + W ++ +A + A L YL N +VH +V NILL
Sbjct 653 MANGDLDEHMSGKRGGSILNWGTRLKIALEAAQGLEYLHNGCKPLMVHRDVKTTNILLNE 712
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVE-----------RIPWLAPECLPGGANSLST 793
KL+D G LSR +E I +L PE N L+
Sbjct 713 -------HFDTKLADFG-----LSRSFPIEGETHVSTVVAGTIGYLDPEYYR--TNWLTE 758
Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
D + FG LL + + Q+R EK H
Sbjct 759 KSDVYSFGVVLLVMITNQPVIDQNR---EKRHI 788
>sp|A8X6H4|CMK1_CAEBR Calcium/calmodulin-dependent protein kinase
type 1 OS=Caenorhabditis briggsae OX=6238 GN=cmk-1 PE=3
SV=4
Length=356
Score = 78.2 bits (191), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 66/218 (30%), Positives = 98/218 (45%), Gaps = 18/218 (8%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
++PA ++ K + + LG G F KV L + G++ AVK +
Sbjct 10 NTPAPTSSIREKYDFRDV--LGTGAFSKVFL---AESKTDVGQLYAVKCIDKKALKGKEE 64
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRD-YLPRHSIGLAQL 1000
+ EI +LR L H +I++ E EK + LVME V G L D + + S
Sbjct 65 SLENEIKVLRKLRHNNIVQ---LFETYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDA 121
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+Q+ E ++++H +HRDL N+L D D + I DFGL+K G V
Sbjct 122 SNLIRQVLEAVSFMHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKTEDSG-----V 176
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+ APE L++ + A DVWS GV Y LL
Sbjct 177 MATACGTPGYVAPEVLQQKPYGKAVDVWSIGVIAYILL 214
>sp|Q55GG4|Y9847_DICDI Probable serine/threonine-protein kinase
DDB_G0267686 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0267686
PE=3 SV=1
Length=2230
Score = 80.5 bits (197), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 71/284 (25%), Positives = 127/284 (45%), Gaps = 28/284 (10%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+ LGEG KV + + VAVK L+++ Q + +E++I+ +L H+
Sbjct 1952 LNKLGEGTSAKVYRATW------RNQEVAVKVLRSEPESQKLLDFLKELEIMSSLRSPHV 2005
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ + G D + ++MEY +L + + + + FA ++ G+ LH+
Sbjct 2006 VYFYGMVLD---PKICMIMEYCSNQTLYHLMHLQMNFTWDWVFKFAIEMVRGVNCLHSWK 2062
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075
+HRDL + N+L+ ++ +K+ DFGL++ R F Y APE
Sbjct 2063 PVIVHRDLKSLNLLVSDNWTIKVADFGLSRFATAKSASNRTTRG----TFAYCAPEVF-- 2116
Query 1076 YKFYYAS-DVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
Y + D++S G+ L+EL C S + P ++F + Q L + +
Sbjct 2117 YGIHTTKGDIFSIGIILWELAVRCIKSKYEKPFSEFKHI------QYDFQILVQTSKFNL 2170
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
R P CP +L+ NCWE+ RP+ ++ L + +KY
Sbjct 2171 RPTIPQNCPEAFSNLISNCWESSPDNRPSCPEILDSLLDMEKKY 2214
Score = 38.9 bits (89), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 68/306 (22%), Positives = 118/306 (39%), Gaps = 57/306 (19%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+D +EI L+ LG+GT VY R QE+ V +
Sbjct 1944 IDGEEIVFLNKLGEGTSAKVYRATW------------------------RNQEVAVKVLR 1979
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+P + L F + +MS + H+ + +G+ V P+ M+ EY + L L +
Sbjct 1980 SEPESQKL-LDFLKELEIMSSLRSPHVVYFYGM-VLDPKICMIMEYCSNQTL-YHLMHLQ 2036
Query 704 GHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
+ W A ++ ++ L + +VH ++ N+L++ + IK++D G
Sbjct 2037 MNFTWDWVFKFAIEMVRGVNCLHSWKPVIVHRDLKSLNLLVSD-------NWTIKVADFG 2089
Query 762 VG--LGALSREERVER--IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ A S R R + APE G +T D + G L E+
Sbjct 2090 LSRFATAKSASNRTTRGTFAYCAPEVFYGIH---TTKGDIFSIGIILWELAVRCIKSKYE 2146
Query 818 RSPSEKEHF------------YQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILR 864
+ SE +H + + +P+ +CP+ + L S C P RPS IL
Sbjct 2147 KPFSEFKHIQYDFQILVQTSKFNLRPTIPQ-NCPEAFSNLISNCWESSPDNRPSCPEILD 2205
Query 865 DLTRLQ 870
L ++
Sbjct 2206 SLLDME 2211
>sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo
sapiens OX=9606 GN=SIK2 PE=1 SV=1
Length=926
Score = 80.1 bits (196), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 63/196 (32%), Positives = 91/196 (46%), Gaps = 13/196 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG+G+F V L + T VA+K + K+ + +E+ I++ L H HIIK
Sbjct 26 LGKGNFAVVKLGRHRITKTE----VAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIK 81
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020
E + L LV EY G + DYL H + ++ QI + Y H + +
Sbjct 82 LYQVMETKS--MLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIV 139
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDL A N+LLDN+ +KI DFG G G P + APE + ++
Sbjct 140 HRDLKAENLLLDNNMNIKIADFGFGNFFKSGE--LLATWCGSPP--YAAPEVFEGQQYEG 195
Query 1081 AS-DVWSFGVTLYELL 1095
D+WS GV LY L+
Sbjct 196 PQLDIWSMGVVLYVLV 211
Score = 47.8 bits (112), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 49/192 (26%), Positives = 79/192 (41%), Gaps = 19/192 (10%)
Query 630 GRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
GR R + V +K++D S D Y +M + H H+ ++ V +VT
Sbjct 37 GRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVT 96
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
EY ++G + +L G + + Q+ SA+ Y + +VH ++ N+LL
Sbjct 97 EYAKNGEIFDYLAN-HGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLL----- 150
Query 748 AEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+ IK++D G G S E P+ APE G +D W G L
Sbjct 151 --DNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYE-GPQLDIWSMGVVL 207
Query 805 -LEIC----FDG 811
+ +C FDG
Sbjct 208 YVLVCGALPFDG 219
>sp|O54784|DAPK3_MOUSE Death-associated protein kinase 3 OS=Mus
musculus OX=10090 GN=Dapk3 PE=1 SV=1
Length=448
Score = 79.0 bits (193), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 63/205 (31%), Positives = 99/205 (48%), Gaps = 20/205 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-----WKQEIDILRTLYH 956
+LG G F V C GTG A K +K P R G ++E+ ILR + H
Sbjct 18 ELGSGQFAIVR-KC---QQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIRH 73
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLH 1015
+II E++ + + L++E V G L D+L + S+ + F +QI +G+ YLH
Sbjct 74 PNIITLHDVFENKTD--VVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131
Query 1016 AQHYIHRDLAARNVLLDNDRL----VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
++ H DL N++L + +K+ DFG+A + G E+ + +P F APE
Sbjct 132 SKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNI---FGTPEF-VAPE 187
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
+ +D+WS GV Y LL+
Sbjct 188 IVNYEPLGLEADMWSIGVITYILLS 212
Score = 37.7 bits (86), Expect = 0.59, Method: Compositional matrix adjust.
Identities = 39/166 (23%), Positives = 71/166 (43%), Gaps = 10/166 (6%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S++ ++ H ++ +H V + +++ E V G L +L E+ + +Q+
Sbjct 66 SILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLA-EKESLTEDEATQFLKQIL 124
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIP 777
+ YL +K + H ++ NI+L SP IKL D G+ + A S + + P
Sbjct 125 DGVHYLHSKRIAHFDLKPENIMLLD---KHAASPRIKLIDFGIAHRIEAGSEFKNIFGTP 181
Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
++APE + L D W G + I G +P + E
Sbjct 182 EFVAPEIV--NYEPLGLEADMWSIG-VITYILLSGASPFLGETKQE 224
>sp|Q9C7T7|CEPR2_ARATH Receptor protein-tyrosine kinase CEPR2
OS=Arabidopsis thaliana OX=3702 GN=CEPR2 PE=1 SV=1
Length=977
Score = 80.1 bits (196), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 69/213 (32%), Positives = 98/213 (46%), Gaps = 37/213 (17%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ--EIDILRTLYHEHII 960
+G G GKV Y G VAVK LK G + E++IL + H +++
Sbjct 689 IGSGSAGKV----YRVDLKKGGGTVAVKWLKRGGGEEGDGTEVSVAEMEILGKIRHRNVL 744
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLR--------------DYLPRHSIGLAQLLLFAQQ 1006
K C +G + LV E++ G+L D+L R+ I +
Sbjct 745 KLYACLVGRGSR--YLVFEFMENGNLYQALGNNIKGGLPELDWLKRYKIAVGA------- 795
Query 1007 ICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+G+AYLH IHRD+ + N+LLD D KI DFG+AK +G+E+ V
Sbjct 796 -AKGIAYLHHDCCPPIIHRDIKSSNILLDGDYESKIADFGVAKVADKGYEWSCVAGTHG- 853
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+ APE +K SDV+SFGV L EL+T
Sbjct 854 ---YMAPELAYSFKATEKSDVYSFGVVLLELVT 883
>sp|Q9SKB2|SBIR1_ARATH Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein
kinase SOBIR1 OS=Arabidopsis thaliana
OX=3702 GN=SOBIR1 PE=1 SV=1
Length=641
Score = 79.7 bits (195), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 50/124 (40%), Positives = 66/124 (53%), Gaps = 9/124 (7%)
Query 976 LVMEYVPLGSLRDYLPRHSIGLAQLL-----LFAQQICEGMAYLHAQH---YIHRDLAAR 1027
LV EY+ GSL+D L G +L+ A I G+ YLH H IHRDL
Sbjct 434 LVYEYMEKGSLQDILTDVQAGNQELMWPARHKIALGIAAGLEYLHMDHNPRIIHRDLKPA 493
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
NVLLD+D +I DFGLAKA+P+ + + V + APE + +KF D++SF
Sbjct 494 NVLLDDDMEARISDFGLAKAMPDAVTHITTSHVAGT-VGYIAPEFYQTHKFTDKCDIYSF 552
Query 1088 GVTL 1091
GV L
Sbjct 553 GVIL 556
>sp|Q7XR88|STRK1_ORYSJ Salt tolerance receptor-like cytoplasmic
kinase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=STRK1
PE=1 SV=2
Length=361
Score = 78.2 bits (191), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 68/211 (32%), Positives = 101/211 (48%), Gaps = 27/211 (13%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEH 958
R +G G F V L + G A+K C + HR+ ++QE+++L +L H H
Sbjct 71 RVIGHGGFSTVYLASLSSSRLG--------AVKVHCSSERLHRA-FRQELEVLLSLRHPH 121
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI--GLAQLLLFAQ------QICEG 1010
I++ G C+++ E LV EY P G L + L + G+A +L +A+ Q+
Sbjct 122 IVRLLGYCDERDEG--VLVFEYAPNGDLHERLHCSEVAGGVASVLPWARRVAIAFQVAMA 179
Query 1011 MAYLHAQHY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--VREDGDSPV 1065
+ YLH + IH D+ A NVLLD + K+ DFG A R R SP
Sbjct 180 LEYLHESRHPAVIHGDIKASNVLLDANMNAKLCDFGFAHVGFSATVGCRPSARAVMGSP- 238
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+ P ++ SDV+SFGV L EL+T
Sbjct 239 GYVDPHLIRSGVATKKSDVYSFGVLLLELVT 269
Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 61/251 (24%), Positives = 97/251 (39%), Gaps = 54/251 (22%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-------- 705
AF + ++ + H H+ + G C E ++V EY +G L ER H
Sbjct 106 AFRQELEVLLSLRHPHIVRLLGYCDERDEGVLVFEYAPNGDL-----HERLHCSEVAGGV 160
Query 706 ---VPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+P A ++ +A Q+A AL YL ++HG++ N+LL + KL D
Sbjct 161 ASVLPWARRVAIAFQVAMALEYLHESRHPAVIHGDIKASNVLL-------DANMNAKLCD 213
Query 760 PG---VGLGAL-----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G VG A S + ++ P + G + + D + FG LLE+
Sbjct 214 FGFAHVGFSATVGCRPSARAVMGSPGYVDPHLIRSGVATKKS--DVYSFGVLLLELVTGK 271
Query 812 EAPLQSR------------SPSEKEHFYQR----QHRLPEPSCPQLATLTSQCLTYEPTQ 855
EA + S + R +H E + +A L QC+ P
Sbjct 272 EAVCRDTGRRLTAAVGPMLSEGKVADVVDRRLGGEHDGAEAAV--MAELAMQCIGDSPGL 329
Query 856 RPSFRTILRDL 866
RPS ++R L
Sbjct 330 RPSMADVVRAL 340
>sp|A2XW02|STRK1_ORYSI Salt tolerance receptor-like cytoplasmic
kinase 1 OS=Oryza sativa subsp. indica OX=39946 GN=OsI_16820
PE=2 SV=1
Length=361
Score = 78.2 bits (191), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 68/211 (32%), Positives = 101/211 (48%), Gaps = 27/211 (13%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEH 958
R +G G F V L + G A+K C + HR+ ++QE+++L +L H H
Sbjct 71 RVIGHGGFSTVYLASLSSSRLG--------AVKVHCSSERLHRA-FRQELEVLLSLRHPH 121
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI--GLAQLLLFAQ------QICEG 1010
I++ G C+++ E LV EY P G L + L + G+A +L +A+ Q+
Sbjct 122 IVRLLGYCDERDEG--VLVFEYAPNGDLHERLHCSEVAGGVASVLPWARRVAIAFQVAMA 179
Query 1011 MAYLHAQHY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--VREDGDSPV 1065
+ YLH + IH D+ A NVLLD + K+ DFG A R R SP
Sbjct 180 LEYLHESRHPAVIHGDIKASNVLLDANMNAKLCDFGFAHVGFSATVGCRPSARAVMGSP- 238
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+ P ++ SDV+SFGV L EL+T
Sbjct 239 GYVDPHLIRSGVATKKSDVYSFGVLLLELVT 269
Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 61/251 (24%), Positives = 97/251 (39%), Gaps = 54/251 (22%)
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-------- 705
AF + ++ + H H+ + G C E ++V EY +G L ER H
Sbjct 106 AFRQELEVLLSLRHPHIVRLLGYCDERDEGVLVFEYAPNGDL-----HERLHCSEVAGGV 160
Query 706 ---VPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+P A ++ +A Q+A AL YL ++HG++ N+LL + KL D
Sbjct 161 ASVLPWARRVAIAFQVAMALEYLHESRHPAVIHGDIKASNVLL-------DANMNAKLCD 213
Query 760 PG---VGLGAL-----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G VG A S + ++ P + G + + D + FG LLE+
Sbjct 214 FGFAHVGFSATVGCRPSARAVMGSPGYVDPHLIRSGVATKKS--DVYSFGVLLLELVTGK 271
Query 812 EAPLQSR------------SPSEKEHFYQR----QHRLPEPSCPQLATLTSQCLTYEPTQ 855
EA + S + R +H E + +A L QC+ P
Sbjct 272 EAVCRDTGRRLTAAVGPMLSEGKVADVVDRRLGGEHDGAEAAV--MAELAMQCIGDSPGL 329
Query 856 RPSFRTILRDL 866
RPS ++R L
Sbjct 330 RPSMADVVRAL 340
>sp|P48609|CDK5_DROME Cyclin-dependent kinase 5 homolog OS=Drosophila
melanogaster OX=7227 GN=Cdk5 PE=1 SV=2
Length=294
Score = 77.0 bits (188), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 62/201 (31%), Positives = 101/201 (50%), Gaps = 16/201 (8%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957
K+ +GEG +G V + N T E+VA+K ++ D + S +EI +L+ L H+
Sbjct 6 KMEKIGEGTYGTV----FKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHK 61
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015
+I++ +K L LV E+ L+ Y + I +A F Q+ G+A+ H
Sbjct 62 NIVRLIDVL--HSDKKLTLVFEHCD-QDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCH 118
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA-PECLK 1074
+ + +HRDL +N+L++ + +K+ DFGLA+A + Y + WY P+ L
Sbjct 119 SHNVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVKCY----SAEVVTLWYRPPDVLF 174
Query 1075 EYKFYYAS-DVWSFGVTLYEL 1094
K Y S D+WS G L EL
Sbjct 175 GAKLYTTSIDMWSAGCILAEL 195
>sp|P49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta OS=Homo
sapiens OX=9606 GN=GSK3B PE=1 SV=2
Length=420
Score = 78.6 bits (192), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 70/208 (34%), Positives = 100/208 (48%), Gaps = 33/208 (16%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V Y +GE+VA+K + D ++R E+ I+R L H +I++
Sbjct 62 IGNGSFGVV----YQAKLCDSGELVAIKKVLQDKRFKNR-----ELQIMRKLDHCNIVRL 112
Query 963 KGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRHSIGLAQLL------LFAQQICEGMA 1012
+ GEK L LV++YVP R + RH Q L L+ Q+ +A
Sbjct 113 RYFFYSSGEKKDEVYLNLVLDYVPETVYR--VARHYSRAKQTLPVIYVKLYMYQLFRSLA 170
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGH---EYYRVREDGDSPVFWY 1068
Y+H+ HRD+ +N+LLD D V K+ DFG AK + G Y R ++
Sbjct 171 YIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR-------YYR 223
Query 1069 APECLKEYKFYYAS-DVWSFGVTLYELL 1095
APE + Y +S DVWS G L ELL
Sbjct 224 APELIFGATDYTSSIDVWSAGCVLAELL 251
Score = 35.8 bits (81), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 27/110 (25%), Positives = 52/110 (47%), Gaps = 10/110 (9%)
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
R + +P+ + + QL +L+Y+ + + H ++ +N+LL + + +KL D
Sbjct 148 RAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLL------DPDTAVLKLCDF 201
Query 761 GVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
G + E V I + APE + GA ++++D W G L E+
Sbjct 202 GSAKQLVRGEPNVSYICSRYYRAPELI-FGATDYTSSIDVWSAGCVLAEL 250
>sp|Q14164|IKKE_HUMAN Inhibitor of nuclear factor kappa-B kinase
subunit epsilon OS=Homo sapiens OX=9606 GN=IKBKE PE=1 SV=1
Length=716
Score = 79.7 bits (195), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 61/206 (30%), Positives = 95/206 (46%), Gaps = 16/206 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G V Y N +GE+VAVK + R +E ++LR L H++I+K
Sbjct 15 LGQGATASV----YKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLRKLNHQNIVKL 70
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMAYLHAQH 1018
E G + LVMEY GSL L P ++ GL + L+ + + GM +L
Sbjct 71 FAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVVAGMNHLRENG 130
Query 1019 YIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPEC 1072
+HRD+ N++ + + K+ DFG A+ + + ++ V E+ P +
Sbjct 131 IVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYLHPDMYERAVL 190
Query 1073 LK--EYKFYYASDVWSFGVTLYELLT 1096
K + F D+WS GVTLY T
Sbjct 191 RKPQQKAFGVTVDLWSIGVTLYHAAT 216
>sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo
sapiens OX=9606 GN=RPS6KA3 PE=1 SV=1
Length=740
Score = 79.7 bits (195), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 62/212 (29%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWK 945
+DP+ F + ++ LG+G FGKV L +D ++ A+K LK A + R K
Sbjct 63 ADPSQF-----ELLKVLGQGSFGKVFLVKKISGSDAR-QLYAMKVLKKATLKVRDRVRTK 116
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ-LLLFA 1004
E DIL + H I+K + +G+ L L+++++ G L L + + + + +
Sbjct 117 MERDILVEVNHPFIVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYL 174
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
++ + +LH+ I+RDL N+LLD + +K+ DFGL+K E ++ +
Sbjct 175 AELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK---ESIDHEKKAYSFCGT 231
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
V + APE + ++D WSFGV ++E+LT
Sbjct 232 VEYMAPEVVNRRGHTQSADWWSFGVLMFEMLT 263
Score = 65.5 bits (158), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 62/185 (34%), Positives = 87/185 (47%), Gaps = 29/185 (16%)
Query 946 QEIDIL-RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLL 1001
+EI+IL R H +II K +D K + +V E + G L D + R S A +
Sbjct 462 EEIEILLRYGQHPNIITLKDVYDDG--KYVYVVTELMKGGELLDKILRQKFFSEREASAV 519
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRV 1057
LF I + + YLHAQ +HRDL N+L N ++I DFG AK +
Sbjct 520 LFT--ITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRA------- 570
Query 1058 REDG--DSPVF---WYAPECLKEYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKF 1108
E+G +P + + APE LK + A D+WS GV LY +LT + P +
Sbjct 571 -ENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEI 629
Query 1109 LELIG 1113
L IG
Sbjct 630 LARIG 634
>sp|O95819|M4K4_HUMAN Mitogen-activated protein kinase kinase
kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP4K4 PE=1 SV=2
Length=1239
Score = 80.5 bits (197), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 58/205 (28%), Positives = 99/205 (48%), Gaps = 22/205 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961
+G G +G+V Y + TG++ A+K + D K EI++L+ +H +I
Sbjct 31 VGNGTYGQV----YKGRHVKTGQLAAIKVM--DVTEDEEEEIKLEINMLKKYSHHRNIAT 84
Query 962 YKGCCEDQG----EKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYL 1014
Y G + + L LVME+ GS+ D + +++ + +++I G+A+L
Sbjct 85 YYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHL 144
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H H IHRD+ +NVLL + VK+ DFG++ + R +W APE +
Sbjct 145 HIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---DRTVGRRNTFIGTPYWMAPEVIA 201
Query 1075 -----EYKFYYASDVWSFGVTLYEL 1094
+ + Y SD+WS G+T E+
Sbjct 202 CDENPDATYDYRSDLWSCGITAIEM 226
Score = 41.2 bits (95), Expect = 0.073, Method: Compositional matrix adjust.
Identities = 55/253 (22%), Positives = 99/253 (39%), Gaps = 32/253 (13%)
Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP------ENIMVTEYVEHGP 694
+KV+D + + E L H ++A +G ++ + +V E+ G
Sbjct 53 IKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGS 112
Query 695 LDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
+ ++ +G+ + W +++++ L++L +++H ++ G+N+LL +
Sbjct 113 ITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTE-------NA 165
Query 754 FIKLSDPGVGLG---ALSREERVERIP-WLAPECLPGGANSLST---AMDKWGFGATLLE 806
+KL D GV + R P W+APE + N +T D W G T +E
Sbjct 166 EVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIE 225
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ------CLTYEPTQRPSFR 860
+ +G PL P R P P CL QRPS
Sbjct 226 MA-EGAPPLCDMHPMRALFLIPRN---PPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTE 281
Query 861 TILRD-LTRLQPH 872
+L+ R QP+
Sbjct 282 QLLKHPFIRDQPN 294
>sp|P18654|KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 OS=Mus
musculus OX=10090 GN=Rps6ka3 PE=1 SV=2
Length=740
Score = 79.7 bits (195), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 62/212 (29%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWK 945
+DP+ F + ++ LG+G FGKV L +D ++ A+K LK A + R K
Sbjct 63 ADPSQF-----ELLKVLGQGSFGKVFLVKKISGSDAR-QLYAMKVLKKATLKVRDRVRTK 116
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ-LLLFA 1004
E DIL + H I+K + +G+ L L+++++ G L L + + + + +
Sbjct 117 MERDILVEVNHPFIVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYL 174
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
++ + +LH+ I+RDL N+LLD + +K+ DFGL+K E ++ +
Sbjct 175 AELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK---ESIDHEKKAYSFCGT 231
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
V + APE + ++D WSFGV ++E+LT
Sbjct 232 VEYMAPEVVNRRGHTQSADWWSFGVLMFEMLT 263
Score = 65.5 bits (158), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 62/185 (34%), Positives = 87/185 (47%), Gaps = 29/185 (16%)
Query 946 QEIDIL-RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLL 1001
+EI+IL R H +II K +D K + +V E + G L D + R S A +
Sbjct 462 EEIEILLRYGQHPNIITLKDVYDDG--KYVYVVTELMKGGELLDKILRQKFFSEREASAV 519
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRV 1057
LF I + + YLHAQ +HRDL N+L N ++I DFG AK +
Sbjct 520 LFT--ITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRA------- 570
Query 1058 REDG--DSPVF---WYAPECLKEYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKF 1108
E+G +P + + APE LK + A D+WS GV LY +LT + P +
Sbjct 571 -ENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEI 629
Query 1109 LELIG 1113
L IG
Sbjct 630 LARIG 634
>sp|Q9WV60|GSK3B_MOUSE Glycogen synthase kinase-3 beta OS=Mus
musculus OX=10090 GN=Gsk3b PE=1 SV=2
Length=420
Score = 78.6 bits (192), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 70/208 (34%), Positives = 100/208 (48%), Gaps = 33/208 (16%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V Y +GE+VA+K + D ++R E+ I+R L H +I++
Sbjct 62 IGNGSFGVV----YQAKLCDSGELVAIKKVLQDKRFKNR-----ELQIMRKLDHCNIVRL 112
Query 963 KGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRHSIGLAQLL------LFAQQICEGMA 1012
+ GEK L LV++YVP R + RH Q L L+ Q+ +A
Sbjct 113 RYFFYSSGEKKDEVYLNLVLDYVPETVYR--VARHYSRAKQTLPVIYVKLYMYQLFRSLA 170
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGH---EYYRVREDGDSPVFWY 1068
Y+H+ HRD+ +N+LLD D V K+ DFG AK + G Y R ++
Sbjct 171 YIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR-------YYR 223
Query 1069 APECLKEYKFYYAS-DVWSFGVTLYELL 1095
APE + Y +S DVWS G L ELL
Sbjct 224 APELIFGATDYTSSIDVWSAGCVLAELL 251
Score = 35.8 bits (81), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 27/110 (25%), Positives = 52/110 (47%), Gaps = 10/110 (9%)
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
R + +P+ + + QL +L+Y+ + + H ++ +N+LL + + +KL D
Sbjct 148 RAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLL------DPDTAVLKLCDF 201
Query 761 GVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
G + E V I + APE + GA ++++D W G L E+
Sbjct 202 GSAKQLVRGEPNVSYICSRYYRAPELI-FGATDYTSSIDVWSAGCVLAEL 250
>sp|P28867|KPCD_MOUSE Protein kinase C delta type OS=Mus musculus
OX=10090 GN=Prkcd PE=1 SV=3
Length=674
Score = 79.7 bits (195), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 66/216 (31%), Positives = 100/216 (46%), Gaps = 37/216 (17%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FGKV L G + A+K LK D + D+ T+ + ++
Sbjct 353 LGKGSFGKVLL----AELKGKDKYFAIKCLKKDVVLI-------DDDVECTMVEKRVLAL 401
Query 963 KG--------CCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAY 1013
C Q + L VME++ G L ++ + L + +A +I G+ +
Sbjct 402 AWESPFLTHLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQF 461
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WY 1068
LH++ I+RDL NV+LD D +KI DFG+ K G +G + F +
Sbjct 462 LHSKGIIYRDLKLDNVMLDRDGHIKIADFGMCKENIFG--------EGRASTFCGTPDYI 513
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
APE L+ K+ ++ D WSFGV LYE+L QSP
Sbjct 514 APEILQGLKYSFSVDWWSFGVLLYEMLI----GQSP 545
>sp|P54666|CC2H3_TRYBB Cell division control protein 2 homolog
3 OS=Trypanosoma brucei brucei OX=5702 GN=CRK3 PE=3 SV=1
Length=311
Score = 77.4 bits (189), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 67/202 (33%), Positives = 96/202 (48%), Gaps = 26/202 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ----EIDILRTLYHEH 958
LGEG +G V Y + TG++VA+K ++ D + G Q E+ IL+ ++H +
Sbjct 29 LGEGTYGVV----YRAVDRATGQIVALKKVRLD---RTDEGIPQTALREVSILQEIHHPN 81
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--FAQQICEGMAYLHA 1016
I+ G+ L L+ EYV L+ L + L Q+ EG+++ H
Sbjct 82 IVNLLDVICADGK--LYLIFEYVD-HDLKKALEKRGGAFTGTTLKKIIYQLLEGLSFCHR 138
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-APECL 1073
+HRDL N+L+ D VKI DFGLA+A +P H Y + WY APE L
Sbjct 139 HRIVHRDLKPANILVTTDNSVKIADFGLARAFQIPM-HTYTH-----EVVTLWYRAPEIL 192
Query 1074 KEYKFYY-ASDVWSFGVTLYEL 1094
K Y A D+WS G EL
Sbjct 193 LGEKHYTPAVDMWSIGCIFAEL 214
Score = 37.0 bits (84), Expect = 1.00, Method: Compositional matrix adjust.
Identities = 57/269 (21%), Positives = 100/269 (37%), Gaps = 44/269 (16%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
R GQ + + LD + I S++ ++ H ++ + V + ++ EYV
Sbjct 43 RATGQIVALKKVRLDRTDEGIPQTALREVSILQEIHHPNIVNLLDVICADGKLYLIFEYV 102
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
+H +R K ++ QL LS+ +VH ++ NIL+
Sbjct 103 DHDLKKALEKRGGAFTGTTLKKII-YQLLEGLSFCHRHRIVHRDLKPANILVT------- 154
Query 751 TSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
T +K++D G+ + + V + + APE L G + A+D W G E
Sbjct 155 TDNSVKIADFGLARAFQIPMHTYTHEVVTLWYRAPEILL-GEKHYTPAVDMWSIGCIFAE 213
Query 807 -----ICFDGEAPLQSR--------SPSEKEHFYQRQHRLPE-----------PSCPQLA 842
+ F G++ + +P + E + LP+ P L
Sbjct 214 LARGKVLFRGDSEIGQLFEIFQVLGTPMDAEGSWLGVSSLPDYRDVFPKWSGKPLTQVLP 273
Query 843 TLT-------SQCLTYEPTQRPSFRTILR 864
TL SQ L Y P +R S + L+
Sbjct 274 TLDGDAVDLLSQMLRYNPAERISAKAALQ 302
>sp|Q9C8I6|IOS1_ARATH LRR receptor-like serine/threonine-protein
kinase IOS1 OS=Arabidopsis thaliana OX=3702 GN=IOS1 PE=1
SV=1
Length=894
Score = 80.1 bits (196), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 75/279 (27%), Positives = 128/279 (46%), Gaps = 22/279 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R LG G FG V Y N+ E VAVK L ++ +K E+++L ++H+ +
Sbjct 590 RVLGRGGFGVV---YYGVLNN---EPVAVKMLTESTALGYKQ-FKAEVELLLRVHHKDLT 642
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA 1016
G CE +G+K + L+ E++ G L+++L + L A + +G+ YLH
Sbjct 643 CLVGYCE-EGDK-MSLIYEFMANGDLKEHLSGKRGPSILTWEGRLRIAAESAQGLEYLHN 700
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+HRD+ N+LL+ K+ DFGL+++ P G E + +P + PE
Sbjct 701 GCKPQIVHRDIKTTNILLNEKFQAKLADFGLSRSFPLGTETHVSTIVAGTPGY-LDPEYY 759
Query 1074 KEYKFYYASDVWSFGVTLYELLTH--CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ SDV+SFGV L EL+T+ + + E +G+ + + + + +G
Sbjct 760 RTNWLTEKSDVFSFGVVLLELVTNQPVIDMKREKSHIAEWVGLMLSRGDINSIVDPKLQG 819
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ P +V C +S RPT ++ LK
Sbjct 820 DFDP---NTIWKVVETAMTCLNPSSSRRPTMTQVVMDLK 855
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 51/181 (28%), Positives = 77/181 (43%), Gaps = 20/181 (11%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K+L S F L+ +V H L + G C G + ++ E++ +G L
Sbjct 610 VAVKMLTESTALGYKQFKAEVELLLRVHHKDLTCLVGYCEEGDKMSLIYEFMANGDLKEH 669
Query 699 LRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSP 753
L +RG + W ++ +A + A L YL N +VH ++ NILL A
Sbjct 670 LSGKRGPSILTWEGRLRIAAESAQGLEYLHNGCKPQIVHRDIKTTNILLNEKFQA----- 724
Query 754 FIKLSDPGVGLG-ALSREERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
KL+D G+ L E V I +L PE N L+ D + FG LLE+
Sbjct 725 --KLADFGLSRSFPLGTETHVSTIVAGTPGYLDPEYYR--TNWLTEKSDVFSFGVVLLEL 780
Query 808 C 808
Sbjct 781 V 781
>sp|Q9QUK0|CDKL2_MOUSE Cyclin-dependent kinase-like 2 OS=Mus musculus
OX=10090 GN=Cdkl2 PE=2 SV=1
Length=568
Score = 79.3 bits (194), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 60/198 (30%), Positives = 101/198 (51%), Gaps = 16/198 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG +G V + C N +G +VA+K L++D + +EI +L+ L HE+++
Sbjct 10 VGEGSYGMV-MKC---RNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65
Query 962 YKGCCEDQGEKSLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
C+ + K LV E+V L L+ + + Q LF QI G+ + H+ +
Sbjct 66 LLEVCKKK--KRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLF--QIINGIGFCHSHN 121
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEYK 1077
IHRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L + K
Sbjct 122 IIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVK 178
Query 1078 FYYASDVWSFGVTLYELL 1095
+ A D+W+ G + E+L
Sbjct 179 YGKAVDIWAIGCLVIEML 196
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 60/245 (24%), Positives = 101/245 (41%), Gaps = 54/245 (22%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ---- 716
L+ Q+ H +L + VC + +V E+V+H LD + P V Q
Sbjct 54 LLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILD-----DLKLFPNGLDYQVVQKYLF 108
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVER 775
Q+ + + + + N++H ++ NIL+++ G+ +KL D G A E +
Sbjct 109 QIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFARTLAAPGEVYTDY 161
Query 776 IP---WLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGEAP----------LQS 817
+ + APE L G A+D W G ++E+ F GE+ L +
Sbjct 162 VATRWYRAPELLVGDV-KYGKAVDIWAIGCLVIEMLMGQPLFPGESDIDQLHHIMTCLGN 220
Query 818 RSPSEKEHFYQR----QHRLPE-------------PSCPQ-LATLTSQCLTYEPTQRPSF 859
P +E FY+ RLPE P P+ + +L +CL +P +RP
Sbjct 221 LIPRHQELFYKNPVFAGVRLPEVKDAEAEPLESRYPKLPEAVISLAKKCLHIDPDKRPFC 280
Query 860 RTILR 864
+LR
Sbjct 281 ADLLR 285
>sp|Q93Z30|BHP_ARATH Serine/threonine-protein kinase 12 OS=Arabidopsis
thaliana OX=3702 GN=BHP PE=1 SV=1
Length=459
Score = 79.0 bits (193), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 73/268 (27%), Positives = 118/268 (44%), Gaps = 48/268 (18%)
Query 924 GEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
G VAVK L + + E+ +L+ L H +I+++ G + +V EY+
Sbjct 178 GIQVAVKKLDDEVLSDDDQVRKFHDELALLQRLRHPNIVQFLGAVTQSN--PMMIVTEYL 235
Query 982 PLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLV 1037
P G LR+ L R + A + +A I GM+YLH IHRDL N+L D+ +
Sbjct 236 PRGDLRELLKRKGQLKPATAVRYALDIARGMSYLHEIKGDPIIHRDLEPSNILRDDSGHL 295
Query 1038 KIGDFGLAKAVPEGHEYYRVREDG-----DSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
K+ DFG++K V V+ED D + APE ++ +DV+SF + +
Sbjct 296 KVADFGVSKLVT-------VKEDKPFTCQDISCRYIAPEVFTSEEYDTKADVFSFALIVQ 348
Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL--TELLERGERLPRP-DKCPCEVY---- 1145
E++ +G+M +E E RP K P + Y
Sbjct 349 EMI--------------------EGRMPFAEKEDSEASEAYAGKHRPLFKAPSKNYPHGL 388
Query 1146 -HLMKNCWETEASFRPTFENLIPILKTV 1172
L++ CW + + RPTF +I L+++
Sbjct 389 KTLIEECWHEKPAKRPTFREIIKRLESI 416
Score = 68.6 bits (166), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 64/252 (25%), Positives = 114/252 (45%), Gaps = 27/252 (11%)
Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
++V +K LD S D F++ +L+ ++ H ++ G + ++VTEY+ G
Sbjct 179 IQVAVKKLDDEVLSDDDQVRKFHDELALLQRLRHPNIVQFLGAVTQSNPMMIVTEYLPRG 238
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYL---ENKNLVHGNVCGRNILLARLGLAEG 750
L L+R +G + A + A +A +SYL + ++H ++ NIL
Sbjct 239 DLRELLKR-KGQLKPATAVRYALDIARGMSYLHEIKGDPIIHRDLEPSNIL-------RD 290
Query 751 TSPFIKLSDPGVGLGALSREER---VERIP--WLAPECLPGGANSLSTAMDKWGFGATLL 805
S +K++D GV +E++ + I ++APE + T D + F +
Sbjct 291 DSGHLKVADFGVSKLVTVKEDKPFTCQDISCRYIAPEVF--TSEEYDTKADVFSFALIVQ 348
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHR----LPEPSCPQ-LATLTSQCLTYEPTQRPSFR 860
E+ +G P + SE Y +HR P + P L TL +C +P +RP+FR
Sbjct 349 EM-IEGRMPFAEKEDSEASEAYAGKHRPLFKAPSKNYPHGLKTLIEECWHEKPAKRPTFR 407
Query 861 TILRDLTRLQPH 872
I++ L + H
Sbjct 408 EIIKRLESILHH 419
>sp|Q8BG48|ST17B_MOUSE Serine/threonine-protein kinase 17B OS=Mus
musculus OX=10090 GN=Stk17b PE=1 SV=1
Length=372
Score = 78.2 bits (191), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 70/242 (29%), Positives = 111/242 (46%), Gaps = 27/242 (11%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
R +++ +LT P +P F+ Y ++LG G F V + TG+
Sbjct 5 RFDCRSVSGLLTTTPQTPIKTEN-FNNFYTLTPKELGRGKFAVVR----QCISKSTGQEY 59
Query 928 AVKALKA-----DCGPQHRSGWKQEIDILRTLYH-EHIIKYKGCCEDQGEKSLQLVMEYV 981
A K+LK DC R+ EI +L H+I E+ E + LV+EY
Sbjct 60 AAKSLKKRRRGQDC----RAEILHEIAVLELARSCPHVINLHEVYENATE--IILVLEYA 113
Query 982 PLGSLRDY-LPR--HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR--- 1035
G + + LP + ++ +QI EG+ YLH + +H DL +N+LL +
Sbjct 114 AGGEIFNLCLPELAEMVSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLG 173
Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+KI DFG+++ + E +RE +P + APE L A+D+W+ G+ Y LL
Sbjct 174 DIKIVDFGMSRKIGNASE---LREIMGTPEYL-APEILNYDPITTATDMWNIGIIAYMLL 229
Query 1096 TH 1097
TH
Sbjct 230 TH 231
Score = 43.1 bits (100), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 49/177 (28%), Positives = 76/177 (43%), Gaps = 27/177 (15%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
R RGQ+ R A +E A L S H+ +H V E I+V EY
Sbjct 67 RRRGQDCR-------------AEILHEIAVLELARSCPHVINLHEVYENATEIILVLEYA 113
Query 691 EHGPL-DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
G + ++ L V + + +Q+ + YL N+VH ++ +NILL+ +
Sbjct 114 AGGEIFNLCLPELAEMVSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSI---- 169
Query 750 GTSPF--IKLSDPGVG--LGALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFG 801
P IK+ D G+ +G S + P +LAPE L + ++TA D W G
Sbjct 170 --YPLGDIKIVDFGMSRKIGNASELREIMGTPEYLAPEIL--NYDPITTATDMWNIG 222
>sp|Q8VYA3|WAKLJ_ARATH Wall-associated receptor kinase-like 10
OS=Arabidopsis thaliana OX=3702 GN=WAKL10 PE=2 SV=1
Length=769
Score = 79.7 bits (195), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 69/221 (31%), Positives = 103/221 (47%), Gaps = 25/221 (11%)
Query 891 VFHKRYLKK-------IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
VF+ R L+K R LGEG G+ ++Y + G +VAVK K
Sbjct 420 VFNSRELEKATENFSLTRILGEG--GQGTVYKGMLVD---GRIVAVKKSKV-VDEDKLEE 473
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--- 1000
+ E+ IL + H +I+K GCC + LV E++P G+L ++L S
Sbjct 474 FINEVVILSQINHRNIVKLLGCCLETDVP--ILVYEFIPNGNLFEHLHDDSDDYTMTTWE 531
Query 1001 --LLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
L A I ++YLH+ HRD+ + N++LD K+ DFG ++ V H +
Sbjct 532 VRLRIAVDIAGALSYLHSAASSPIYHRDIKSTNIMLDEKHRAKVSDFGTSRTVTVDHTHL 591
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
G V + PE + +F SDV+SFGV L EL+T
Sbjct 592 TTVVSG--TVGYMDPEYFQSSQFTDKSDVYSFGVVLAELIT 630
Score = 44.3 bits (103), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 71/342 (21%), Positives = 133/342 (39%), Gaps = 77/342 (23%)
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
G S R N +L + +T++ LG+G + VY+G L ++ K+ DED
Sbjct 413 GNVDSTRVFNSRELE-KATENFSLTRI--LGEGGQGTVYKGMLVDGRIVAVKKSKVVDED 469
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
L F ++SQ++H ++ + G C+ I+
Sbjct 470 KLEE-------------------------FINEVVILSQINHRNIVKLLGCCLETDVPIL 504
Query 686 VTEYVEHGPLDVWLRRERGHVPM-AW--KMVVAQQLASALSYLENKN---LVHGNVCGRN 739
V E++ +G L L + M W ++ +A +A ALSYL + + H ++ N
Sbjct 505 VYEFIPNGNLFEHLHDDSDDYTMTTWEVRLRIAVDIAGALSYLHSAASSPIYHRDIKSTN 564
Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE----------RIPWLAPECLPGGAN 789
I+L A K+SD G SR V+ + ++ PE ++
Sbjct 565 IMLDEKHRA-------KVSDFGT-----SRTVTVDHTHLTTVVSGTVGYMDPEYFQ--SS 610
Query 790 SLSTAMDKWGFGATLLEICFDGEAPL------QSRSPSEKEHFYQRQHRLPE-------- 835
+ D + FG L E+ GE + + R+ + +++RL +
Sbjct 611 QFTDKSDVYSFGVVLAEL-ITGEKSVSFLRSQEYRTLATYFTLAMKENRLSDIIDARIRD 669
Query 836 ----PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
A + +CL + +RPS R + +L +++ ++
Sbjct 670 GCKLNQVTAAAKIARKCLNMKGRKRPSMRQVSMELEKIRSYS 711
>sp|O88764|DAPK3_RAT Death-associated protein kinase 3 OS=Rattus
norvegicus OX=10116 GN=Dapk3 PE=1 SV=1
Length=448
Score = 79.0 bits (193), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 63/205 (31%), Positives = 99/205 (48%), Gaps = 20/205 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-----WKQEIDILRTLYH 956
+LG G F V C GTG A K +K P R G ++E+ ILR + H
Sbjct 18 ELGSGQFAIVR-KC---QQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIRH 73
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLH 1015
+II E++ + + L++E V G L D+L + S+ + F +QI +G+ YLH
Sbjct 74 PNIITLHDVFENKTD--VVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131
Query 1016 AQHYIHRDLAARNVLLDNDRL----VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
++ H DL N++L + +K+ DFG+A + G E+ + +P F APE
Sbjct 132 SKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNI---FGTPEF-VAPE 187
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
+ +D+WS GV Y LL+
Sbjct 188 IVNYEPLGLEADMWSIGVITYILLS 212
Score = 37.7 bits (86), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 39/166 (23%), Positives = 71/166 (43%), Gaps = 10/166 (6%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S++ ++ H ++ +H V + +++ E V G L +L E+ + +Q+
Sbjct 66 SILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLA-EKESLTEDEATQFLKQIL 124
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIP 777
+ YL +K + H ++ NI+L SP IKL D G+ + A S + + P
Sbjct 125 DGVHYLHSKRIAHFDLKPENIMLLD---KHAASPRIKLIDFGIAHRIEAGSEFKNIFGTP 181
Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
++APE + L D W G + I G +P + E
Sbjct 182 EFVAPEIV--NYEPLGLEADMWSIG-VITYILLSGASPFLGETKQE 224
>sp|Q9TTK0|CDKL2_RABIT Cyclin-dependent kinase-like 2 OS=Oryctolagus
cuniculus OX=9986 GN=CDKL2 PE=2 SV=1
Length=566
Score = 79.3 bits (194), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 63/199 (32%), Positives = 102/199 (51%), Gaps = 18/199 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG +G V + C N +G +VA+K L++D + +EI +L+ L HE+++
Sbjct 10 VGEGSYGMV-MKC---RNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL----AQLLLFAQQICEGMAYLHAQ 1017
C+ + K LV E+V ++ D L GL Q LF QI G+ + H+
Sbjct 66 LLEVCKKK--KRWYLVFEFVD-HTILDDLELFPNGLDDQVVQKYLF--QIINGIGFCHSH 120
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEY 1076
+ IHRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L +
Sbjct 121 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDV 177
Query 1077 KFYYASDVWSFGVTLYELL 1095
K+ A DVW+ G + E+L
Sbjct 178 KYGKAVDVWAIGCLVTEML 196
Score = 41.6 bits (96), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 56/236 (24%), Positives = 96/236 (41%), Gaps = 52/236 (22%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ---- 716
L+ Q+ H +L + VC + +V E+V+H LD + P V Q
Sbjct 54 LLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILD-----DLELFPNGLDDQVVQKYLF 108
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVER 775
Q+ + + + + N++H ++ NIL+++ G+ +KL D G A E +
Sbjct 109 QIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFARTLAAPGEVYTDY 161
Query 776 IP---WLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGEAPLQ----------S 817
+ + APE L G A+D W G + E+ F G++ + +
Sbjct 162 VATRWYRAPELLVGDV-KYGKAVDVWAIGCLVTEMLMGEPLFPGDSDIDQLYLIMRCLGN 220
Query 818 RSPSEKEHFYQR----QHRLPEPS--------CPQLA----TLTSQCLTYEPTQRP 857
P +E FY+ RLPE P+L+ L +CL +P +RP
Sbjct 221 LIPRHQELFYKNPVFAGVRLPEIKESEPLERRYPKLSEVVIDLAKKCLHVDPDKRP 276
>sp|Q55DD4|PAKD_DICDI Serine/threonine-protein kinase pakD OS=Dictyostelium
discoideum OX=44689 GN=pakD PE=3 SV=1
Length=1678
Score = 80.1 bits (196), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 66/224 (29%), Positives = 101/224 (45%), Gaps = 41/224 (18%)
Query 897 LKKIRDL-GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
L K+R++ G G GKV Y N TGE VA+K +K D EI ++
Sbjct 1375 LYKVREVVGGGSTGKV----YVGENSITGEKVAIKKMKVDNNNIKNII--NEISTMKNSK 1428
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL------------------ 997
H+++IKY + L+MEY+ GSL D L + I +
Sbjct 1429 HKNVIKY--VSSHLVINHIWLIMEYMSYGSLTD-LISNCINIQCNGNNQQQQQQQQQQQT 1485
Query 998 ----AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ + QQ+ +GM Y+H H HRD+ + N+LL D VKI DFG +
Sbjct 1486 YFIESHIAYICQQVLQGMDYIHKGHRTHRDIKSDNILLGKDGSVKIADFGFVANLT---- 1541
Query 1054 YYRVREDGDSPV---FWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
R + +S V ++ APE ++ ++ + D+WS G+ EL
Sbjct 1542 --RKKLQRNSVVGTPYFMAPELIRGNQYNHKVDIWSLGILAREL 1583
Score = 34.3 bits (77), Expect = 9.4, Method: Compositional matrix adjust.
Identities = 37/160 (23%), Positives = 65/160 (41%), Gaps = 20/160 (13%)
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSR 769
+ QQ+ + Y+ + H ++ NILL + G +K++D G + L R
Sbjct 1495 ICQQVLQGMDYIHKGHRTHRDIKSDNILLGKDG-------SVKIADFGFVANLTRKKLQR 1547
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
V ++APE + G N + +D W G E+ +GE P ++ P + F
Sbjct 1548 NSVVGTPYFMAPELIRG--NQYNHKVDIWSLGILARELS-EGEPPY-AKYPPVRALFLLT 1603
Query 830 QHRLPEPSCPQ-----LATLTSQCLTYEPTQRPSFRTILR 864
+P+ P + CL + +RP +LR
Sbjct 1604 LEGVPDFKEPNKWSSDFIEFVNLCLNLDDKRRPDAHYLLR 1643
>sp|P12965|MOS_XENLA Serine/threonine-protein kinase mos OS=Xenopus
laevis OX=8355 GN=mos PE=2 SV=1
Length=359
Score = 77.8 bits (190), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 80/306 (26%), Positives = 127/306 (42%), Gaps = 50/306 (16%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHE 957
+ LG G FG V Y GE VA+K +K R + E++ R L H
Sbjct 66 LEPLGSGGFGSVYRATY------RGETVALKKVKRSTKNSLASRQSFWAELNAAR-LRHP 118
Query 958 HIIKY----KGCCEDQGEKSLQLVMEYVPLGSL--RDYLPRHSIGLAQLLLFAQQICEGM 1011
H+++ C D G ++MEY G+L R Y +G + +A+ + +G+
Sbjct 119 HVVRVVAASASCPGDPGCPG-TIIMEYTGTGTLHQRIYGRSPPLGAEICMRYARHVADGL 177
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-------YRVREDGDSP 1064
+LH +H DL NVLL L KIGDFG ++ + EG E ++R G +
Sbjct 178 RFLHRDGVVHLDLKPANVLLAPGDLCKIGDFGCSQRLREGDEAAGGEPCCTQLRHVGGT- 236
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
APE LK +D++SF +TL++++ ++ L G Q + +
Sbjct 237 YTHRAPELLKGEPVTAKADIYSFAITLWQMV----------SRELPYTGDRQCVLYAVVA 286
Query 1125 TELLERGERLPRPDKCPC--------EVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
+L RP+ P ++++CW RP E L+ L+
Sbjct 287 YDL--------RPEMGPLFSHTEEGRAARTIVQSCWAARPQERPNAEQLLERLEQECAMC 338
Query 1177 QGQAPS 1182
G PS
Sbjct 339 TGGPPS 344
>sp|O22932|CIPKB_ARATH CBL-interacting serine/threonine-protein
kinase 11 OS=Arabidopsis thaliana OX=3702 GN=CIPK11 PE=1 SV=1
Length=435
Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 70/231 (30%), Positives = 112/231 (48%), Gaps = 28/231 (12%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL---KA 934
+ + S ++ +F K L K+ LG G F KV + + TG+ VAVK L K
Sbjct 4 IEIAAGSGDNNDALFGKYELGKL--LGCGAFAKV----FHARDRRTGQSVAVKILNKKKL 57
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994
P + K+EI I+R L H +I+K + + + ME+V G L + + +H
Sbjct 58 LTNPALANNIKREISIMRRLSHPNIVKLHEVMATKSK--IFFAMEFVKGGELFNKISKHG 115
Query 995 IGLAQLL--LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
L++ L + QQ+ + Y HA+ HRDL N+L+D + +K+ DFGL+ +
Sbjct 116 -RLSEDLSRRYFQQLISAVGYCHARGVYHRDLKPENLLIDENGNLKVSDFGLSALTDQ-- 172
Query 1053 EYYRVREDG------DSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096
+R DG +P + APE L + + A DVWS G+ L+ L+
Sbjct 173 ----IRPDGLLHTLCGTPA-YVAPEILSKKGYEGAKVDVWSCGIVLFVLVA 218
Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 58/248 (23%), Positives = 101/248 (41%), Gaps = 25/248 (10%)
Query 631 RDRGQELRVVLKVLDP----SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
RDR V +K+L+ ++ +A S+M ++SH ++ +H V +
Sbjct 39 RDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHPNIVKLHEVMATKSKIFFA 98
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
E+V+ G L + + G + QQL SA+ Y + + H ++ N+L+ G
Sbjct 99 MEFVKGGELFNKISKH-GRLSEDLSRRYFQQLISAVGYCHARGVYHRDLKPENLLIDENG 157
Query 747 LAEGTSPFIKLSDPGVGLGALSREERVERI--------PWLAPECLPGGANSLSTAMDKW 798
+K+SD GL AL+ + R + + ++APE L +D W
Sbjct 158 -------NLKVSD--FGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYE-GAKVDVW 207
Query 799 GFGATLLEICFDGEAPLQS-RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857
G L + G P + + Y+ ++R P P L S+ L P R
Sbjct 208 SCGIVLF-VLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRFVSRLLDINPETRI 266
Query 858 SFRTILRD 865
+ IL+D
Sbjct 267 TIDEILKD 274
>sp|Q8C0V7|SMKW_MOUSE Putative sperm motility kinase W OS=Mus
musculus OX=10090 GN=Stk-ps2 PE=5 SV=2
Length=499
Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 69/207 (33%), Positives = 98/207 (47%), Gaps = 26/207 (13%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
K + LG G FG V L C+ T +VA+K + + ++ G + EI L L H
Sbjct 15 KVLFTLGHGSFGTVKLACHLKTK----ALVAIKMV--ELSKKNIRGIRAEIATLEKLQHP 68
Query 958 HIIKYKGCCEDQ---GEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEG 1010
+II C Q K + +V EY+P G+L D + P H ++ Q+
Sbjct 69 NII-----CLFQVLVTSKHINIVTEYIPGGNLFDIIKEDGPMHEEEARRIF---GQVVSA 120
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
+ Y H Q +H+D+ A+N+L D + VKI DFGLA G R+ G F AP
Sbjct 121 VKYCHNQDIVHQDIKAQNILRDEEGNVKIIDFGLAIRCRSG--TLLKRQCGTKSCF--AP 176
Query 1071 E-CLKEYKFYYASDVWSFGVTLYELLT 1096
E L+E +DVWS GV LY + T
Sbjct 177 ELVLQEPYDGKKADVWSLGVLLYFITT 203
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 60/231 (26%), Positives = 98/231 (42%), Gaps = 17/231 (7%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K+++ S +I E A+L ++ H ++ + V V +VTEY+ G L
Sbjct 40 VAIKMVELSKKNIRGIRAEIATL-EKLQHPNIICLFQVLVTSKHINIVTEYIPGGNL-FD 97
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ +E G + + Q+ SA+ Y N+++VH ++ +NIL G +K+
Sbjct 98 IIKEDGPMHEEEARRIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEG-------NVKII 150
Query 759 DPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
D G+ + G L + + + APE + A D W G LL G P
Sbjct 151 DFGLAIRCRSGTLLKRQCGTK-SCFAPELVLQEPYDGKKA-DVWSLG-VLLYFITTGYYP 207
Query 815 LQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ + E +E + +P QL L Q LT P RPS I R
Sbjct 208 FRGSTMKEMEEKIATGTYDIPTHVSGQLENLIHQILTVPPEMRPSIEDIER 258
>sp|P06493|CDK1_HUMAN Cyclin-dependent kinase 1 OS=Homo sapiens
OX=9606 GN=CDK1 PE=1 SV=3
Length=297
Score = 77.0 bits (188), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 62/234 (26%), Positives = 113/234 (48%), Gaps = 25/234 (11%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957
KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L H
Sbjct 6 KIEKIGEGTYGVV----YKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAY 1013
+I+ + + L L+ E++ + L+ YL P + + + + QI +G+ +
Sbjct 62 NIVSLQDVL--MQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWYAPE 1071
H++ +HRDL +N+L+D+ +K+ DFGLA+A +P RV +++ +PE
Sbjct 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP-----IRVYTHEVVTLWYRSPE 173
Query 1072 C-LKEYKFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQM 1119
L ++ D+WS G EL T H DS + +G ++
Sbjct 174 VLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV 227
>sp|Q8S8Y9|WNK2_ARATH Serine/threonine-protein kinase WNK2 OS=Arabidopsis
thaliana OX=3702 GN=WNK2 PE=1 SV=1
Length=568
Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 56/164 (34%), Positives = 90/164 (55%), Gaps = 10/164 (6%)
Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SI 995
P+ + +EI +L+TL H++I+K+ D S+ V E G+LR Y RH +
Sbjct 63 NPEELEKFFREIHLLKTLNHQNIMKFYTSWVDTNNLSINFVTELFTSGTLRQYRLRHRRV 122
Query 996 GLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFGLAKAVPEGH 1052
+ + + +QI +G+ YLH++ IHRDL N+ ++ N VKIGD GLA + + H
Sbjct 123 NIRAVKQWCKQILKGLLYLHSRSPPIIHRDLKCDNIFINGNQGEVKIGDLGLAAILRKSH 182
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
VR G +P F APE E ++ DV++FG+ + E++T
Sbjct 183 A---VRCVG-TPEF-MAPEVYDE-EYNELVDVYAFGMCVLEMVT 220
>sp|P48734|CDK1_BOVIN Cyclin-dependent kinase 1 OS=Bos taurus
OX=9913 GN=CDK1 PE=2 SV=2
Length=297
Score = 77.0 bits (188), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 61/215 (28%), Positives = 108/215 (50%), Gaps = 25/215 (12%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957
KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L H
Sbjct 6 KIEKIGEGTYGVV----YKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAY 1013
+I+ + + L L+ E++ + L+ YL P + + + + QI +G+ +
Sbjct 62 NIVSLQDVL--MQDSRLYLIFEFLSM-DLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVF 118
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWYAPE 1071
H++ +HRDL +N+L+D+ +K+ DFGLA+A +P RV +++ +PE
Sbjct 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP-----IRVYTHEVVTLWYRSPE 173
Query 1072 C-LKEYKFYYASDVWSFGVTLYELLT-----HCDS 1100
L ++ D+WS G EL T H DS
Sbjct 174 VLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDS 208
>sp|Q12469|SKM1_YEAST Serine/threonine-protein kinase SKM1 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=SKM1 PE=1 SV=1
Length=655
Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 53/184 (29%), Positives = 89/184 (48%), Gaps = 17/184 (9%)
Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY-KGCCEDQGEKSLQLVMEYV 981
GE VA+K ++ P+ + E+ ++ E+I+ + + D E L ++MEY+
Sbjct 399 VGERVAIKQIRLSEQPK-KQLIMNELLVMNDSRQENIVNFLEAYIIDDEE--LWVIMEYM 455
Query 982 PLGSLRDYLP--------RHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031
G L D L HS + Q+ ++ C+G+ +LH + IHRD+ + N+LL
Sbjct 456 EGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILL 515
Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091
++ LVKI DFG + E R +W APE + + + DVWS G+ L
Sbjct 516 NSQGLVKITDFGFCVELTEKRSK---RATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIML 572
Query 1092 YELL 1095
E++
Sbjct 573 IEMI 576
Score = 52.0 bits (123), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 51/212 (24%), Positives = 84/212 (40%), Gaps = 30/212 (14%)
Query 670 LAFVHGVCVRGPENIMVTEYVEHG----PLDVWLRRERGH--VPMAWKMV--VAQQLASA 721
+ F+ + E ++ EY+E G LD R G P+ + + ++
Sbjct 435 VNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQG 494
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---- 777
L +L NK ++H ++ NILL GL +K++D G + E+R +R
Sbjct 495 LKFLHNKKIIHRDIKSDNILLNSQGL-------VKITDFGFCVELT--EKRSKRATMVGT 545
Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR----QH 831
W+APE + +D W G L+E+ +GE P + P + + +
Sbjct 546 PYWMAPEIV--NQKGYDEKVDVWSLGIMLIEM-IEGEPPYLNEDPLKALYLIANNGSPKL 602
Query 832 RLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
R PE Q CL R S R +L
Sbjct 603 RHPESVSKQTKQFLDACLQVNVESRASVRKLL 634
>sp|Q93ZS4|NIK3_ARATH Protein NSP-INTERACTING KINASE 3 OS=Arabidopsis
thaliana OX=3702 GN=NIK3 PE=1 SV=1
Length=632
Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 67/203 (33%), Positives = 97/203 (48%), Gaps = 19/203 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG-PQHRSGWKQEIDILRTLYHEHIIK 961
LG G +G V NDGT +VAVK LK DC ++ E++ + H ++++
Sbjct 307 LGRGGYGIV---YKGHLNDGT--LVAVKRLK-DCNIAGGEVQFQTEVETISLALHRNLLR 360
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHA 1016
+G C E+ L V Y+P GS+ L + ++ ++ A G+ YLH
Sbjct 361 LRGFCSSNQERIL--VYPYMPNGSVASRLKDNIRGEPALDWSRRKKIAVGTARGLVYLHE 418
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
Q IHRD+ A N+LLD D +GDFGLAK + H V V APE L
Sbjct 419 QCDPKIIHRDVKAANILLDEDFEAVVGDFGLAKLLD--HRDSHVTTAVRGTVGHIAPEYL 476
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
+ +DV+ FG+ L EL+T
Sbjct 477 STGQSSEKTDVFGFGILLLELIT 499
>sp|Q9FJ54|CIPKK_ARATH CBL-interacting serine/threonine-protein
kinase 20 OS=Arabidopsis thaliana OX=3702 GN=CIPK20 PE=1 SV=1
Length=439
Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 63/201 (31%), Positives = 96/201 (48%), Gaps = 14/201 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYH 956
R LG+G F KV Y N TGE VA+K + D + G K+EI ++R + H
Sbjct 16 RLLGQGTFAKV----YHARNIKTGESVAIKVI--DKQKVAKVGLIDQIKREISVMRLVRH 69
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016
H++ + + + MEYV G L D + + + + QQ+ + Y H+
Sbjct 70 PHVVFLHEVMASKTK--IYFAMEYVKGGELFDKVSKGKLKENIARKYFQQLIGAIDYCHS 127
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ HRDL N+LLD + +KI DFGL+ + + +P + APE + +
Sbjct 128 RGVYHRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPAY-VAPEVIGKK 186
Query 1077 KFYYA-SDVWSFGVTLYELLT 1096
+ A +DVWS GV LY LL
Sbjct 187 GYDGAKADVWSCGVVLYVLLA 207
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 65/280 (23%), Positives = 107/280 (38%), Gaps = 43/280 (15%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LGQGT VY R G E + D+ + +V L +D +I
Sbjct 18 LGQGTFAKVYHARNIKTG-----------ESVAIKVIDKQKVAKVGL--IDQIKREI--- 61
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
S+M V H H+ F+H V + EYV+ G L + + +G +
Sbjct 62 -----SVMRLVRHPHVVFLHEVMASKTKIYFAMEYVKGGEL--FDKVSKGKLKENIARKY 114
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
QQL A+ Y ++ + H ++ N+LL G +K+SD GL AL ++ +
Sbjct 115 FQQLIGAIDYCHSRGVYHRDLKPENLLLDENGD-------LKISD--FGLSALRESKQQD 165
Query 775 RI--------PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EH 825
+ ++APE + G D W G L + G P ++ E
Sbjct 166 GLLHTTCGTPAYVAPEVI-GKKGYDGAKADVWSCGVVLY-VLLAGFLPFHEQNLVEMYRK 223
Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ + + P P++ L S+ L P R I+ +
Sbjct 224 ITKGEFKCPNWFPPEVKKLLSRILDPNPNSRIKIEKIMEN 263
>sp|Q7Y0B9|SAPK8_ORYSJ Serine/threonine-protein kinase SAPK8 OS=Oryza
sativa subsp. japonica OX=39947 GN=SAPK8 PE=1 SV=1
Length=371
Score = 77.8 bits (190), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 78/238 (33%), Positives = 115/238 (48%), Gaps = 25/238 (11%)
Query 885 PASDPTVFHK--RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
P D + H RY + +RD+G G+FG L + T E+VAVK ++ G +
Sbjct 20 PGMDMPIMHDSDRY-ELVRDIGSGNFGVARLM----RDRRTMELVAVKYIER--GEKIDD 72
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLL 1001
++EI R+L H +II++K L +VMEY G L + + ++ +
Sbjct 73 NVQREIINHRSLKHPNIIRFKEVI--LTPTHLAIVMEYASGGELFERICKNVRFSEDEAR 130
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVR 1058
F QQ+ G++Y H+ HRDL N LLD RL KI DFG +K+ + + +
Sbjct 131 YFFQQLISGVSYCHSMQVCHRDLKLENTLLDGSPAPRL-KICDFGYSKS---SVLHSQPK 186
Query 1059 EDGDSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLELI 1112
+P + APE L KEY A DVWS GVTLY ++ + P P F + I
Sbjct 187 STVGTPA-YIAPEVLLKKEYDGKTA-DVWSCGVTLYVMVVGAYPFEDPEEPKNFRKTI 242
Score = 34.3 bits (77), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 35/138 (25%), Positives = 59/138 (43%), Gaps = 14/138 (10%)
Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER 775
QQL S +SY + VC R++ L L +P +K+ D G ++ +
Sbjct 134 QQLISGVSYCHSM-----QVCHRDLKLENTLLDGSPAPRLKICDFGYSKSSVLHSQPKST 188
Query 776 I---PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832
+ ++APE L TA D W G TL + G P + P E ++F + R
Sbjct 189 VGTPAYIAPEVLLKKEYDGKTA-DVWSCGVTLY-VMVVGAYPFE--DPEEPKNFRKTIQR 244
Query 833 L--PEPSCPQLATLTSQC 848
+ + S P+ ++ +C
Sbjct 245 ILNVQYSIPENVDISPEC 262
>sp|P93101|CDC2_OXYRB Cell division control protein 2 homolog
OS=Oxybasis rubra OX=3560 GN=CDC2 PE=2 SV=1
Length=294
Score = 76.6 bits (187), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 63/208 (30%), Positives = 100/208 (48%), Gaps = 20/208 (10%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYH 956
+K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ + H
Sbjct 5 EKVEKIGEGTYGVV----YKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR--DYLPRHSIGLAQLLLFAQQICEGMAYL 1014
+I++ + EK L LV EY+ L + D P + + F QI G+AY
Sbjct 61 GNIVRLQDVV--HSEKRLYLVFEYLDLDLKKHMDSCPDFAKDPRMIKRFLYQILRGIAYC 118
Query 1015 HAQHYIHRDLAARNVLLD-NDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070
H+ +HRDL +N+L+D +K+ DFGLA+A +P + V WY AP
Sbjct 119 HSHRVLHRDLKPQNLLIDRQTNALKLADFGLARAFGIPVRTFTHEV------VTLWYRAP 172
Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTH 1097
E L + Y DVWS G E++
Sbjct 173 EILLGSRHYSTPVDVWSVGCIFAEMVNQ 200
>sp|P35567|CDK1A_XENLA Cyclin-dependent kinase 1-A OS=Xenopus
laevis OX=8355 GN=cdk1-a PE=1 SV=1
Length=302
Score = 77.0 bits (188), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 66/235 (28%), Positives = 113/235 (48%), Gaps = 27/235 (11%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957
KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L H
Sbjct 6 KIEKIGEGTYGVV----YKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61
Query 958 HIIKYKGCCED--QGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLL--FAQQICEGM 1011
+I+ C D + L L+ E++ + L+ YL G + +L+ + QI +G+
Sbjct 62 NIV----CLLDVLMQDSRLYLIFEFLSM-DLKKYLDSIPSGQYIDTMLVKSYLYQILQGI 116
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-AP 1070
+ H++ +HRDL +N+L+D+ ++K+ DFGLA+A Y + WY AP
Sbjct 117 VFCHSRRVLHRDLKPQNLLIDSKGVIKLADFGLARAFGIPVRVYT----HEVVTLWYRAP 172
Query 1071 EC-LKEYKFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQM 1119
E L ++ DVWS G E+ T H DS + +G ++
Sbjct 173 EVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEV 227
>sp|Q55CL6|MP2K1_DICDI Dual specificity mitogen-activated protein
kinase kinase 1 OS=Dictyostelium discoideum OX=44689 GN=mekA
PE=1 SV=1
Length=660
Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 60/200 (30%), Positives = 100/200 (50%), Gaps = 13/200 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
LK IR LG G G V L ++ + G +A+K + D R E+ L +
Sbjct 292 LKIIRVLGRGAGGVVKLAYHETS----GTYIALKVITLDIQENIRKQIILELKTLHKTSY 347
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLH 1015
+I+ + +G S+ + +E++ LGSL D + + S I L A Q+ +G+ YLH
Sbjct 348 PYIVSFYDAFYTEG--SIFIALEFMELGSLSDIMKKTSTIPEPVLGKIAFQVLQGLVYLH 405
Query 1016 AQ-HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR-VREDGDSPVFWYAPECL 1073
+ H IHRD+ N+L++N KI DFG++ + H + V G V + +PE +
Sbjct 406 RKLHLIHRDIKPSNILVNNKGEAKIADFGVSGQLQ--HTLSKAVTWVG--TVTYMSPERI 461
Query 1074 KEYKFYYASDVWSFGVTLYE 1093
+ + S++WS G+T+ E
Sbjct 462 SGRSYSFDSEIWSLGLTILE 481
>sp|X5M8U1|GCY17_CAEEL Receptor-type guanylate cyclase gcy-17
OS=Caenorhabditis elegans OX=6239 GN=gcy-17 PE=2 SV=1
Length=1088
Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 70/274 (26%), Positives = 133/274 (49%), Gaps = 27/274 (10%)
Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972
Y Y N+ E+VA A K D PQ + E+ +R+L H+++ K+ G C + +
Sbjct 564 FYIYQVRNN---EVVA--ANKHDFRPQLTDVERSELRQMRSLDHDNLNKFIGLCLNS--Q 616
Query 973 SLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYLHAQH-YIHRDLAARNV 1029
L + Y GSL D + R S+ + + + + I G+ ++H + H L++R+
Sbjct 617 QLLSIWRYCSRGSLADVISRSSMQMDSFFMLSLIRDIANGLGFIHTSMLHFHGYLSSRSC 676
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFYYASDVWSFG 1088
L+D+ VKI DFGL +E + + + W+APE L+ + +D++SFG
Sbjct 677 LIDDRWQVKISDFGL-------NEVRGMDKLSTENMLWWAPEVLRGLEQRSKEADIYSFG 729
Query 1089 VTLYELLTHCDSS--QSPPTKFLELI-GIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
+ E++T + ++ K E+I + +G +R + L + + P V
Sbjct 730 IICSEVITRSSAFDLENRKEKPEEIIYQLKKGGFNAIRPSLLTDEALEIN-----PALV- 783
Query 1146 HLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
HL+++CW + S RP + + +L+ +++ +G
Sbjct 784 HLIRDCWTEKPSERPPIDQVRSLLRGMNDGKKGN 817
Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 57/236 (24%), Positives = 95/236 (40%), Gaps = 33/236 (14%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA 721
M + H +L G+C+ + + + Y G L + R + + + + + +A+
Sbjct 597 MRSLDHDNLNKFIGLCLNSQQLLSIWRYCSRGSLADVISRSSMQMDSFFMLSLIRDIANG 656
Query 722 LSYLENKNL-VHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREERVERI 776
L ++ L HG + R+ L+ +K+SD G+ G+ LS E +
Sbjct 657 LGFIHTSMLHFHGYLSSRSCLI-------DDRWQVKISDFGLNEVRGMDKLS----TENM 705
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA-PLQSRSPSEKEHFYQRQH---R 832
W APE L G S D + FG E+ A L++R +E YQ +
Sbjct 706 LWWAPEVLRG-LEQRSKEADIYSFGIICSEVITRSSAFDLENRKEKPEEIIYQLKKGGFN 764
Query 833 LPEPSC---------PQLATLTSQCLTYEPTQRP---SFRTILRDLTRLQPHNLAD 876
PS P L L C T +P++RP R++LR + + NL D
Sbjct 765 AIRPSLLTDEALEINPALVHLIRDCWTEKPSERPPIDQVRSLLRGMNDGKKGNLMD 820
>sp|Q5WA76|PUB70_ORYSJ U-box domain-containing protein 70 OS=Oryza
sativa subsp. japonica OX=39947 GN=PUB70 PE=1 SV=1
Length=805
Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 61/205 (30%), Positives = 98/205 (48%), Gaps = 23/205 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG V VA+K L+ D Q +S ++QE+ IL + H H++
Sbjct 451 IGEGGFGCVYKGIL------RNMTVAIKVLRPD-SLQGQSQFEQEVSILSRVRHPHLVTL 503
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
G C + S LV E++P GSL D+L R ++ + +IC + +LH
Sbjct 504 LGACSE----SSTLVYEFLPNGSLEDFLMCSDKRQTLTWQARIRIIAEICSALIFLHKNK 559
Query 1019 ---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH----EYYRVREDGDSPVFWYAPE 1071
+H DL N+LL + + K+ DFG+++ + + YR +P++ PE
Sbjct 560 PHPVVHGDLKPANILLGVNLVSKLSDFGISRLLIQSSTNNTTLYRTMHPVGTPLYM-DPE 618
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
L + SDV+SFG+ + LLT
Sbjct 619 FLSTGELTPQSDVYSFGIVVLRLLT 643
Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 49/196 (25%), Positives = 88/196 (45%), Gaps = 27/196 (14%)
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+ + V +KVL P F + S++S+V H HL + G C + +V E++ +G
Sbjct 465 RNMTVAIKVLRPDSLQGQSQFEQEVSILSRVRHPHLVTLLGAC--SESSTLVYEFLPNGS 522
Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAE 749
L+ +L + W ++ + ++ SAL +L +VHG++ NILL
Sbjct 523 LEDFLMCSDKRQTLTWQARIRIIAEICSALIFLHKNKPHPVVHGDLKPANILL------- 575
Query 750 GTSPFIKLSDPGVG---LGALSREERVERIP-------WLAPECLPGGANSLSTAMDKWG 799
G + KLSD G+ + + + + R ++ PE L G L+ D +
Sbjct 576 GVNLVSKLSDFGISRLLIQSSTNNTTLYRTMHPVGTPLYMDPEFLSTG--ELTPQSDVYS 633
Query 800 FGATLLEICFDGEAPL 815
FG +L + G+ P+
Sbjct 634 FGIVVLRL-LTGKPPV 648
>sp|P23572|CDK1_DROME Cyclin-dependent kinase 1 OS=Drosophila
melanogaster OX=7227 GN=Cdk1 PE=1 SV=1
Length=297
Score = 76.6 bits (187), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 63/208 (30%), Positives = 100/208 (48%), Gaps = 20/208 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955
+KI +GEG +G V Y N TG++VA+K ++ + + S +EI +L+ L
Sbjct 4 FEKIEKIGEGTYGVV----YKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELK 59
Query 956 HEHIIKYKGCCED--QGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLL-FAQQICEG 1010
HE+I+ C ED E + L+ E++ L D LP ++L+ + QI
Sbjct 60 HENIV----CLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSA 115
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-A 1069
+ + H + +HRDL +N+L+D L+K+ DFGL ++ Y + WY A
Sbjct 116 ILFCHRRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYT----HEIVTLWYRA 171
Query 1070 PECLKEYKFYYA-SDVWSFGVTLYELLT 1096
PE L Y D+WS G E+ T
Sbjct 172 PEVLLGSPRYSCPVDIWSIGCIFAEMAT 199
Score = 37.0 bits (84), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 64/317 (20%), Positives = 125/317 (39%), Gaps = 76/317 (24%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ ++ +G+GT VY+GR R+ G ++ +++ +D VP
Sbjct 2 EDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVP---------------- 45
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ A E SL+ ++ H ++ + V + ++ E+ L + L++
Sbjct 46 ------STAIREI-SLLKELKHENIVCLEDVLMEENRIYLIFEF-----LSMDLKKYMDS 93
Query 706 VPMAWKM------VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+P+ M Q+ SA+ + + ++H ++ +N+L+ + GL IK++D
Sbjct 94 LPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSGL-------IKVAD 146
Query 760 PGVG--LGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FD 810
G+G G R + + + APE L G S +D W G E+ F
Sbjct 147 FGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPR-YSCPVDIWSIGCIFAEMATRKPLFQ 205
Query 811 GEAPLQS--------RSPSEK-----EHFYQRQHRLPEPSCPQLAT-----------LTS 846
G++ + ++P+E ++ P S QL L
Sbjct 206 GDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDANGIDLIQ 265
Query 847 QCLTYEPTQRPSFRTIL 863
+ L Y+P R S + IL
Sbjct 266 KMLIYDPVHRISAKDIL 282
>sp|Q8SRU0|CSK2A_ENCCU Probable casein kinase II subunit alpha
homolog OS=Encephalitozoon cuniculi (strain GB-M1) OX=284813
GN=CKA1 PE=3 SV=1
Length=319
Score = 77.0 bits (188), Expect = 1e-13, Method: Composition-based stats.
Identities = 54/177 (31%), Positives = 93/177 (53%), Gaps = 20/177 (11%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
E + +KALK P ++ +E+ ILR L H++IIK D + L+ EY+
Sbjct 59 EKIVIKALK----PVRKAKICREVLILRNLSHKNIIKLMDVVVDPESQIYSLIFEYI--- 111
Query 985 SLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL-VKIGDF 1042
DY + ++ +++QI ++Y H+ IHRD+ +N++++ R +KI D+
Sbjct 112 EHEDYAKIFEKLCYKDIVEYSRQILSALSYCHSMGIIHRDIKPQNMVINQARRELKIIDW 171
Query 1043 GLAKAVPEGHEYYRVREDGDSPV---FWYAPECLKEYKFY-YASDVWSFGVTLYELL 1095
GLA E+Y +++ V ++ PE L +Y +Y Y+ D+WSFG L EL+
Sbjct 172 GLA-------EFYHPKKEYSVRVASRYYKGPELLVDYPYYDYSLDIWSFGCVLAELV 221
>sp|Q5N942|SAPK4_ORYSJ Serine/threonine-protein kinase SAPK4 OS=Oryza
sativa subsp. japonica OX=39947 GN=SAPK4 PE=2 SV=2
Length=360
Score = 77.8 bits (190), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 73/203 (36%), Positives = 100/203 (49%), Gaps = 20/203 (10%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+RD+G G+FG L N T E+VAVK ++ G + +EI R+L H +I
Sbjct 7 VRDIGSGNFGVARLM----RNRETRELVAVKCIER--GHRIDENVYREIINHRSLRHPNI 60
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I++K L +VME+ G L D + R + F QQ+ G++Y H
Sbjct 61 IRFKEVI--LTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVSYCHHMQ 118
Query 1019 YIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-- 1073
HRDL NVLLD RL KI DFG +K+ + R + +P + APE L
Sbjct 119 ICHRDLKLENVLLDGSPAPRL-KICDFGYSKS---SVLHSRPKSAVGTPAY-IAPEVLSR 173
Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096
+EY A DVWS GVTLY +L
Sbjct 174 REYDGKLA-DVWSCGVTLYVMLV 195
>sp|P28582|CDPK_DAUCA Calcium-dependent protein kinase OS=Daucus
carota OX=4039 PE=2 SV=2
Length=532
Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 64/209 (31%), Positives = 102/209 (49%), Gaps = 30/209 (14%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHE- 957
++LG G FG V Y T + +G++ A K++ + + K+EI IL+ L +
Sbjct 85 KELGRGQFGCV----YQCTENSSGQLYACKSILKRKLVSKNDKEDIKREIQILQHLSGQP 140
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-------YLPRHSIGLAQLLLFAQQICEG 1010
+I+++KG ED+ +S+ LVME G L D Y R + + + ++ +C
Sbjct 141 NIVEFKGVFEDR--QSVHLVMELCAGGELFDRIIAQGHYSERAAATICRQIVNVVHVC-- 196
Query 1011 MAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
H +HRDL N LL D D ++K DFGL+ + EG Y + ++
Sbjct 197 ----HFMGVMHRDLKPENFLLSSKDKDAMLKATDFGLSVFIEEGKVYRNIV----GSAYY 248
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096
APE L+ + D+WS GV LY LL+
Sbjct 249 VAPEVLRR-SYGKEIDIWSAGVILYILLS 276
>sp|Q03002|FRK1_YEAST Fatty acyl-CoA synthetase and RNA processing-associated
kinase 1 OS=Saccharomyces cerevisiae (strain
ATCC 204508 / S288c) OX=559292 GN=FRK1 PE=1 SV=1
Length=865
Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 66/206 (32%), Positives = 104/206 (50%), Gaps = 19/206 (9%)
Query 903 LGEGHFGKVSL---YCYDPTNDGTGEM---VAVKALKADC-GPQHRSGWK--QEIDILRT 953
LGEG FGKV L + +++ T + VA+K +K D +R K +EI+ L+
Sbjct 47 LGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKH 106
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGM 1011
L H +I+K + Q + + +V+EY G Y+ R + LF+Q I G+
Sbjct 107 LSHPNIVKLEEVL--QNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLIS-GV 163
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
Y+H++ +HRDL N+LLD + + I DFG +E ++ SP + APE
Sbjct 164 HYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNEL--MKTSCGSPCYA-APE 220
Query 1072 CLKEYKFYYA--SDVWSFGVTLYELL 1095
+ + Y A +D+WS GV LY +L
Sbjct 221 LVISAEPYEARKADIWSCGVILYAIL 246
>sp|Q6FN53|STE20_CANGA Serine/threonine-protein kinase STE20 OS=Candida
glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761
/ NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=STE20 PE=3
SV=1
Length=915
Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 55/200 (28%), Positives = 100/200 (50%), Gaps = 13/200 (7%)
Query 899 KIRDL---GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
K RDL G+G G V + + D VA+K + + P+ + EI ++R
Sbjct 619 KYRDLIKIGQGASGGVYIAHDTESEDS----VAIKQMNLEKQPK-KELILNEILVMRESK 673
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH 1015
H +I+ + +G+ L +VMEY+ GSL D + + Q+ ++ +G+ +LH
Sbjct 674 HSNIVNFIDSYLAKGD--LWIVMEYMEGGSLTDVVTHCLLSEGQIGAVCRETLKGLQFLH 731
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
++ +HRD+ + N+LL +K+ DFG + E + R G +P +W APE +
Sbjct 732 SKGVLHRDIKSDNILLSLKGNIKLTDFGFCAQINENN-LKRTTMVG-TP-YWMAPEVVSR 788
Query 1076 YKFYYASDVWSFGVTLYELL 1095
++ D+WS G+ + E++
Sbjct 789 KEYGPKVDIWSLGIMIIEMI 808
>sp|Q92772|CDKL2_HUMAN Cyclin-dependent kinase-like 2 OS=Homo
sapiens OX=9606 GN=CDKL2 PE=1 SV=1
Length=493
Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 63/199 (32%), Positives = 101/199 (51%), Gaps = 18/199 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG +G V + C N TG +VA+K L++D + +EI +L+ L HE+++
Sbjct 10 VGEGSYGMV-MKC---RNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL----AQLLLFAQQICEGMAYLHAQ 1017
C + +K LV E+V ++ D L GL Q LF QI G+ + H+
Sbjct 66 LLEVC--KKKKRWYLVFEFVD-HTILDDLELFPNGLDYQVVQKYLF--QIINGIGFCHSH 120
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEY 1076
+ IHRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L +
Sbjct 121 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDV 177
Query 1077 KFYYASDVWSFGVTLYELL 1095
K+ A DVW+ G + E+
Sbjct 178 KYGKAVDVWAIGCLVTEMF 196
Score = 40.0 bits (92), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 41/160 (26%), Positives = 70/160 (44%), Gaps = 22/160 (14%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ---- 716
L+ Q+ H +L + VC + +V E+V+H LD + P V Q
Sbjct 54 LLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILD-----DLELFPNGLDYQVVQKYLF 108
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVER 775
Q+ + + + + N++H ++ NIL+++ G+ +KL D G A E +
Sbjct 109 QIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFARTLAAPGEVYTDY 161
Query 776 IP---WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
+ + APE L G A+D W G + E+ F GE
Sbjct 162 VATRWYRAPELLVGDV-KYGKAVDVWAIGCLVTEM-FMGE 199
>sp|Q16975|KPC2_APLCA Calcium-independent protein kinase C OS=Aplysia
californica OX=6500 GN=PRKC2 PE=1 SV=1
Length=743
Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 62/205 (30%), Positives = 95/205 (46%), Gaps = 23/205 (11%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
I+ LG+G FGKV L GT E+ A+K LK D Q+ D+ T+ + I
Sbjct 406 IKVLGKGSFGKVML----AEKKGTDEVYAIKVLKKDV-------IIQDDDVECTMTEKRI 454
Query 960 IKYKGC--------CEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEG 1010
+ Q ++ L VMEYV G L + R + +A ++
Sbjct 455 LALSAKHPFLTALHSSFQTKERLFFVMEYVNGGDLMFQIQRARKFDEPRARFYAAEVTLA 514
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
+ +LH I+RDL N+LLD + KI DFG+ K EG ++ + + AP
Sbjct 515 LMFLHRHGIIYRDLKLDNILLDAEGHCKIADFGMCK---EGMTENKLTQTFCGTPDYIAP 571
Query 1071 ECLKEYKFYYASDVWSFGVTLYELL 1095
E L+E K+ + D W+ GV +YE++
Sbjct 572 EILQELKYDASVDWWALGVLMYEMM 596
>sp|P19525|E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated
protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2
PE=1 SV=2
Length=551
Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 76/282 (27%), Positives = 126/282 (45%), Gaps = 48/282 (17%)
Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY---LKKIRDLGEGHFGKVSLYCYDPT 919
LR+ R +LA + PD + TV KR+ K+I +G G FG+V +
Sbjct 232 LRNNQRKAKRSLAPRFDL-PDMKETKYTV-DKRFGMDFKEIELIGSGGFGQV----FKAK 285
Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGC----------CEDQ 969
+ G+ +K +K + R E+ L L H +I+ Y GC +D
Sbjct 286 HRIDGKTYVIKRVKYNNEKAER-----EVKALAKLDHVNIVHYNGCWDGFDYDPETSDDS 340
Query 970 GEKS-----------------LQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFA--QQICE 1009
E S L + ME+ G+L ++ R L ++L +QI +
Sbjct 341 LESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITK 400
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
G+ Y+H++ IHRDL N+ L + + VKIGDFGL ++ ++ R R G + + +
Sbjct 401 GVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLK--NDGKRTRSKG--TLRYMS 456
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111
PE + + D+++ G+ L ELL CD++ F +L
Sbjct 457 PEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDL 498
Score = 43.5 bits (101), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 41/190 (22%), Positives = 83/190 (44%), Gaps = 29/190 (15%)
Query 688 EYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
E+ + G L+ W+ + RG + + + +Q+ + Y+ +K L+H ++ NI L
Sbjct 367 EFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFLV--- 423
Query 747 LAEGTSPFIKLSDPGVGLGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFG- 801
+ +K+ D G+ + +L + + R + +++PE + + +D + G
Sbjct 424 ----DTKQVKIGDFGL-VTSLKNDGKRTRSKGTLRYMSPEQIS--SQDYGKEVDLYALGL 476
Query 802 --ATLLEICFDGEAPLQSRSPSEKEHFYQ--RQHRLPEPSCPQLATLTSQCLTYEPTQRP 857
A LL +C + E F+ R + + + TL + L+ +P RP
Sbjct 477 ILAELLHVC---------DTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRP 527
Query 858 SFRTILRDLT 867
+ ILR LT
Sbjct 528 NTSEILRTLT 537
>sp|O81292|LRK43_ARATH L-type lectin-domain containing receptor
kinase IV.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK43 PE=2
SV=1
Length=674
Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 66/201 (33%), Positives = 99/201 (49%), Gaps = 21/201 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---EIDILRTLYHEHI 959
LG G FG+V Y T + +AVK + + R G K+ EI + + H ++
Sbjct 361 LGSGGFGRV----YRGVMPTTKKEIAVKRVSN----ESRQGLKEFVAEIVSIGRMSHRNL 412
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA 1016
+ G C + E L LV +Y+P GSL YL P ++ Q + G+ YLH
Sbjct 413 VPLLGYCRRRDE--LLLVYDYMPNGSLDKYLYDCPEVTLDWKQRFNVIIGVASGLFYLHE 470
Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
Q IHRD+ A NVLLD + ++GDFGLA+ G + R G + AP+ +
Sbjct 471 EWEQVVIHRDIKASNVLLDAEYNGRLGDFGLARLCDHGSDPQTTRVVGTWG--YLAPDHV 528
Query 1074 KEYKFYYASDVWSFGVTLYEL 1094
+ + A+DV++FGV L E+
Sbjct 529 RTGRATTATDVFAFGVLLLEV 549
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 57/234 (24%), Positives = 102/234 (44%), Gaps = 40/234 (17%)
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK--MVVAQQLA 719
+ ++SH +L + G C R E ++V +Y+ +G LD +L + V + WK V +A
Sbjct 404 IGRMSHRNLVPLLGYCRRRDELLLVYDYMPNGSLDKYL-YDCPEVTLDWKQRFNVIIGVA 462
Query 720 SALSYLE---NKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREERVER 775
S L YL + ++H ++ N+LL A G +L D G + + R
Sbjct 463 SGLFYLHEEWEQVVIHRDIKASNVLLDAEYNGRLGDFGLARLCDHG-------SDPQTTR 515
Query 776 IP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF----- 826
+ +LAP+ + G +TA D + FG LLE+ G P++ S++
Sbjct 516 VVGTWGYLAPDHVRTG--RATTATDVFAFGVLLLEVAC-GRRPIEIEIESDESVLLVDSV 572
Query 827 --YQRQHRLPEPSCPQLATLTSQ------------CLTYEPTQRPSFRTILRDL 866
+ + + + + P L ++ Q C +P RP+ R +L+ L
Sbjct 573 FGFWIEGNILDATDPNLGSVYDQREVETVLKLGLLCSHSDPQVRPTMRQVLQYL 626
>sp|Q8VYY5|NCRK_ARATH Receptor-like serine/threonine-protein kinase
NCRK OS=Arabidopsis thaliana OX=3702 GN=NCRK PE=1 SV=1
Length=565
Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 82/275 (30%), Positives = 120/275 (44%), Gaps = 37/275 (13%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ--LVMEYV 981
G+ A+K L G + + E+++L L+H H++ G C + K + LV EY+
Sbjct 232 GKTAAIKRLNTPKGDDTDTLFSTEVELLSRLHHYHVVPLIGYCSEFHGKHAERLLVFEYM 291
Query 982 PLGSLRDYLPRHSIGLAQLLLFAQQI------CEGMAYLH---AQHYIHRDLAARNVLLD 1032
GSLRD L L + + + +I G+ YLH A +HRD+ + N+LLD
Sbjct 292 SYGSLRDCLDGE---LGEKMTWNIRISVALGAARGLEYLHEAAAPRILHRDVKSTNILLD 348
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-------WYAPECLKEYKFYYASDVW 1085
+ KI D G+AK + ++ SP ++APE SDV+
Sbjct 349 ENWHAKITDLGMAKCLSSDG----LQSGSSSPTTGLQGTFGYFAPEYAIAGCASQMSDVF 404
Query 1086 SFGVTLYELLTHCDSSQSPP-TKFLELIGIAQGQMTVLRLTELLERGERLPRP---DKCP 1141
SFGV L EL+T Q P K E + I V RL + E LP P K
Sbjct 405 SFGVVLLELITGRKPIQKPSNNKGEESLVI----WAVPRLQDSKRVIEELPDPRLNGKFA 460
Query 1142 CEVYHLM----KNCWETEASFRPTFENLIPILKTV 1172
E +M K C + RPT ++ IL T+
Sbjct 461 EEEMQIMAYLAKECLLLDPESRPTMREVVQILSTI 495
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 85/347 (24%), Positives = 144/347 (41%), Gaps = 79/347 (23%)
Query 569 ASPRTLN--LSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
+ P T++ + Q S+ ++Q + + S +G G + VY G+L+ +GK
Sbjct 186 SKPETIHGAIFQFSYTELEQATNKFSSNSVIGHGGSSCVYRGQLK--------DGKT--- 234
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV----RG 680
+ ++ P D F L+S++ H H+ + G C +
Sbjct 235 -------------AAIKRLNTPKGDDTDTLFSTEVELLSRLHHYHVVPLIGYCSEFHGKH 281
Query 681 PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA--LSYLENK---NLVHGNV 735
E ++V EY+ +G L L E G M W + ++ L +A L YL ++H +V
Sbjct 282 AERLLVFEYMSYGSLRDCLDGELGE-KMTWNIRISVALGAARGLEYLHEAAAPRILHRDV 340
Query 736 CGRNILL--------ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPE-CLP 785
NILL LG+A+ LS G+ G+ S ++ + APE +
Sbjct 341 KSTNILLDENWHAKITDLGMAKC------LSSDGLQSGSSSPTTGLQGTFGYFAPEYAIA 394
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--------QRQHR----L 833
G A+ +S D + FG LLE+ G P+Q S ++ E Q R L
Sbjct 395 GCASQMS---DVFSFGVVLLEL-ITGRKPIQKPSNNKGEESLVIWAVPRLQDSKRVIEEL 450
Query 834 PEP---------SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P+P +A L +CL +P RP+ R +++ L+ + P
Sbjct 451 PDPRLNGKFAEEEMQIMAYLAKECLLLDPESRPTMREVVQILSTITP 497
>sp|Q940H6|SRK2E_ARATH Serine/threonine-protein kinase SRK2E OS=Arabidopsis
thaliana OX=3702 GN=SRK2E PE=1 SV=1
Length=362
Score = 77.4 bits (189), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 78/238 (33%), Positives = 113/238 (47%), Gaps = 26/238 (11%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
P P + + ++D+G G+FG L + + E+VAVK ++ G +
Sbjct 9 PMDLPIMHDSDRYELVKDIGSGNFGVARLM----RDKQSNELVAVKYIER--GEKIDENV 62
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLL 1001
K+EI R+L H +I+++K L +VMEY G L + + R S A+
Sbjct 63 KREIINHRSLRHPNIVRFKEVI--LTPTHLAIVMEYASGGELFERICNAGRFSEDEARF- 119
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVR 1058
F QQ+ G++Y HA HRDL N LLD RL KI DFG +K+ + + +
Sbjct 120 -FFQQLISGVSYCHAMQVCHRDLKLENTLLDGSPAPRL-KICDFGYSKS---SVLHSQPK 174
Query 1059 EDGDSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLELI 1112
+P + APE L KEY A DVWS GVTLY +L + P P F + I
Sbjct 175 STVGTPA-YIAPEVLLKKEYDGKVA-DVWSCGVTLYVMLVGAYPFEDPEEPKNFRKTI 230
>sp|Q5R754|CDKL2_PONAB Cyclin-dependent kinase-like 2 OS=Pongo
abelii OX=9601 GN=CDKL2 PE=2 SV=1
Length=493
Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 63/199 (32%), Positives = 101/199 (51%), Gaps = 18/199 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG +G V + C N TG +VA+K L++D + +EI +L+ L HE+++
Sbjct 10 VGEGSYGMV-MKC---RNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL----AQLLLFAQQICEGMAYLHAQ 1017
C+ + K LV E+V ++ D L GL Q LF QI G+ + H+
Sbjct 66 LLEVCKKK--KRWYLVFEFVD-HTILDDLELFPNGLDYQVVQKYLF--QIINGIGFCHSH 120
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEY 1076
+ IHRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L +
Sbjct 121 NIIHRDIKPENILVSKSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDV 177
Query 1077 KFYYASDVWSFGVTLYELL 1095
K+ A DVW+ G + E+
Sbjct 178 KYGKAVDVWAIGCLVTEMF 196
Score = 43.1 bits (100), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 57/236 (24%), Positives = 96/236 (41%), Gaps = 52/236 (22%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ---- 716
L+ Q+ H +L + VC + +V E+V+H LD + P V Q
Sbjct 54 LLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILD-----DLELFPNGLDYQVVQKYLF 108
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVER 775
Q+ + + + + N++H ++ NIL+++ G+ +KL D G A E +
Sbjct 109 QIINGIGFCHSHNIIHRDIKPENILVSKSGV-------VKLCDFGFARTLAAPGEVYTDY 161
Query 776 IP---WLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGEAP----------LQS 817
+ + APE L G A+D W G + E+ F G++ L +
Sbjct 162 VATRWYRAPELLVGDV-KYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGN 220
Query 818 RSPSEKEHFYQR----QHRLPEPS--------CPQLA----TLTSQCLTYEPTQRP 857
P +E FY+ RLPE P+L+ L +CL +P +RP
Sbjct 221 LIPRHQELFYKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRP 276
>sp|Q8IBS5|CDPK4_PLAF7 Calcium-dependent protein kinase 4 OS=Plasmodium
falciparum (isolate 3D7) OX=36329 GN=CDPK4 PE=1 SV=3
Length=528
Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 67/219 (31%), Positives = 108/219 (49%), Gaps = 25/219 (11%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQE 947
VF+++Y K I+ LG+G FG+V L + TG A+K + K + +E
Sbjct 64 VVFNEQY-KGIKILGKGSFGEVIL----SRDKHTGHEYAIKVISKKHVKRKTDKESLLRE 118
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLF 1003
+++L+ L H +I+K ED LV + G L D + + I A+++
Sbjct 119 VELLKMLDHINIMKLYEFFEDNN--YYYLVSDVYTGGELFDEIISRKRFYEIDAARII-- 174
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDN----DRLVKIGDFGLAKAVPEGHEYYRVRE 1059
+QI G+ Y+H + +HRDL N+LL+ D ++KI DFGL+ EY + +
Sbjct 175 -KQILSGITYMHKNNVVHRDLKPENILLETKNKEDMIIKIIDFGLSTHF----EYSKKMK 229
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
D ++ AP+ L + D+WS GV LY LL+ C
Sbjct 230 DKIGTAYYIAPDVL-HGTYDEKCDIWSCGVILYILLSGC 267
>sp|O23082|CRK44_ARATH Cysteine-rich receptor-like protein kinase
44 OS=Arabidopsis thaliana OX=3702 GN=CRK44 PE=3 SV=2
Length=379
Score = 77.8 bits (190), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 63/210 (30%), Positives = 99/210 (47%), Gaps = 16/210 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG V D +GE +AVK L G Q + + E+ ++ L H ++++
Sbjct 62 LGEGGFGAVYKGVLD-----SGEEIAVKRLSMKSG-QGDNEFVNEVSLVAKLQHRNLVRL 115
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
G C +GE+ L L+ E+ SL ++ R + + + G+ YLH
Sbjct 116 LGFCF-KGEERL-LIYEFFKNTSLEKFIFDSDRRMILDWEKRYRIISGVARGLLYLHEDS 173
Query 1019 Y---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074
+ IHRD+ A NVLLD+ KI DFG+ K + + + Y APE
Sbjct 174 HFKIIHRDMKASNVLLDDAMNPKIADFGMVKLFNTDQTSQTMFTSKVAGTYGYMAPEYAM 233
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
+F +DV+SFGV + E++ ++ SP
Sbjct 234 SGQFSVKTDVFSFGVLVLEIIKGKKNNWSP 263
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 67/325 (21%), Positives = 130/325 (40%), Gaps = 67/325 (21%)
Query 576 LSQLSFH--RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L QL F R+ + + +HLG+G VY+G L D
Sbjct 41 LLQLDFDTIRLATNDFSPYNHLGEGGFGAVYKGVL-----------------------DS 77
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
G+E+ V + D F SL++++ H +L + G C +G E +++ E+ ++
Sbjct 78 GEEIAVKRLSMKSGQGDNE--FVNEVSLVAKLQHRNLVRLLGFCFKGEERLLIYEFFKNT 135
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
L+ ++ + + W + + +A L YL + H + R++ + + L +
Sbjct 136 SLEKFIFDSDRRMILDWEKRYRIISGVARGLLYLHEDS--HFKIIHRDMKASNVLLDDAM 193
Query 752 SPFIKLSDPGV----GLGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGAT 803
+P K++D G+ S+ ++ ++APE G S+ T D + FG
Sbjct 194 NP--KIADFGMVKLFNTDQTSQTMFTSKVAGTYGYMAPEYAMSGQFSVKT--DVFSFGVL 249
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQH-----------RLPEPSCPQLATLTSQ----- 847
+LEI + + SP E+ + + + +PS + L+ +
Sbjct 250 VLEII---KGKKNNWSPEEQSSLFLLSYVWKCWREGEVLNIVDPSLIETRGLSDEIRKCI 306
Query 848 -----CLTYEPTQRPSFRTILRDLT 867
C+ P RP+ +I+R L
Sbjct 307 HIGLLCVQENPGSRPTMASIVRMLN 331
>sp|Q9S7U9|M2K2_ARATH Mitogen-activated protein kinase kinase
2 OS=Arabidopsis thaliana OX=3702 GN=MKK2 PE=1 SV=2
Length=363
Score = 77.4 bits (189), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 65/241 (27%), Positives = 115/241 (48%), Gaps = 29/241 (12%)
Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922
+R +++L+P L+ P PA D L ++ +G+G G V L +
Sbjct 44 VRIISQLEPEVLS------PIKPADDQLSLSD--LDMVKVIGKGSSGVVQLVQHK----W 91
Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982
TG+ A+K ++ + R QE+ I ++ +++ D G ++ L++EY+
Sbjct 92 TGQFFALKVIQLNIDEAIRKAIAQELKINQSSQCPNLVTSYQSFYDNG--AISLILEYMD 149
Query 983 LGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLH-AQHYIHRDLAARNVLLDNDRLVKIG 1040
GSL D+L +I + L +Q+ +G+ YLH +H IHRDL N+L+++ VKI
Sbjct 150 GGSLADFLKSVKAIPDSYLSAIFRQVLQGLIYLHHDRHIIHRDLKPSNLLINHRGEVKIT 209
Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVF-----WYAPECLKEYKFYYASDVWSFGVTLYELL 1095
DFG++ + G + F + +PE + K+ SD+WS G+ + E
Sbjct 210 DFGVSTVM--------TNTAGLANTFVGTYNYMSPERIVGNKYGNKSDIWSLGLVVLECA 261
Query 1096 T 1096
T
Sbjct 262 T 262
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 45/198 (23%), Positives = 87/198 (44%), Gaps = 32/198 (16%)
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE-NKNLVHGNVCGRNILLA 743
++ EY++ G L +L+ + +P ++ + +Q+ L YL +++++H ++ N+L+
Sbjct 143 LILEYMDGGSLADFLKSVKA-IPDSYLSAIFRQVLQGLIYLHHDRHIIHRDLKPSNLLIN 201
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWG 799
G +K++D GV + V +++PE + G N D W
Sbjct 202 HRGE-------VKITDFGVSTVMTNTAGLANTFVGTYNYMSPERIVG--NKYGNKSDIWS 252
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE----------PS---CPQLATLTS 846
G +LE C G+ P +P +E + L E PS P+L++ S
Sbjct 253 LGLVVLE-CATGKFPY---APPNQEETWTSVFELMEAIVDQPPPALPSGNFSPELSSFIS 308
Query 847 QCLTYEPTQRPSFRTILR 864
CL +P R S + ++
Sbjct 309 TCLQKDPNSRSSAKELME 326
>sp|Q4R7T5|CDKL2_MACFA Cyclin-dependent kinase-like 2 OS=Macaca
fascicularis OX=9541 GN=CDKL2 PE=2 SV=1
Length=570
Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 63/199 (32%), Positives = 101/199 (51%), Gaps = 18/199 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG +G V + C N TG +VA+K L++D + +EI +L+ L HE+++
Sbjct 10 VGEGSYGMV-VKC---RNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL----AQLLLFAQQICEGMAYLHAQ 1017
C + +K LV E+V ++ D L GL Q LF QI G+ + H+
Sbjct 66 LLEVC--KKKKRWYLVFEFVD-HTILDDLELFPNGLDYQVVQKYLF--QIINGIGFCHSH 120
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEY 1076
+ IHRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L +
Sbjct 121 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDV 177
Query 1077 KFYYASDVWSFGVTLYELL 1095
K+ A DVW+ G + E+
Sbjct 178 KYGKAVDVWAIGCLVTEMF 196
Score = 42.4 bits (98), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 56/236 (24%), Positives = 96/236 (41%), Gaps = 52/236 (22%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ---- 716
L+ Q+ H +L + VC + +V E+V+H LD + P V Q
Sbjct 54 LLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILD-----DLELFPNGLDYQVVQKYLF 108
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVER 775
Q+ + + + + N++H ++ NIL+++ G+ +KL D G A E +
Sbjct 109 QIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFARTLAAPGEVYTDY 161
Query 776 IP---WLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGEAPLQ----------S 817
+ + APE L G A+D W G + E+ F G++ + +
Sbjct 162 VATRWYRAPELLVGDV-KYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGN 220
Query 818 RSPSEKEHFYQR----QHRLPEPS--------CPQLA----TLTSQCLTYEPTQRP 857
P +E FY+ RLPE P+L+ L +CL +P +RP
Sbjct 221 LIPRHQELFYKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRP 276
>sp|Q99014|KPC1_HYPJE Protein kinase C-like OS=Hypocrea jecorina
OX=51453 GN=pkc1 PE=3 SV=1
Length=1139
Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 58/198 (29%), Positives = 89/198 (45%), Gaps = 14/198 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-----SGWKQEIDILRTLYHE 957
LG+G+FGKV L + + A+K LK + ++ K+ I H
Sbjct 820 LGKGNFGKVML----AETKRSKRLFAIKVLKKEFIIENDEVESIKSEKRVFLIANRERHP 875
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ C Q E + VMEY+ G L ++ R G + +A ++C + Y H
Sbjct 876 FLTNLHACF--QTETRVYFVMEYISGGDLMLHIQRGQFGTKRAQFYAAEVCLALKYFHEN 933
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
I+RDL N++L D +KI D+GL K E Y + APE L + K
Sbjct 934 GVIYRDLKLDNIMLTLDGHIKIADYGLCK---EDMWYGSTTSTFCGTPEFMAPEILLDKK 990
Query 1078 FYYASDVWSFGVTLYELL 1095
+ A D W+FGV +Y++L
Sbjct 991 YGRAVDWWAFGVLIYQML 1008
>sp|Q54WW7|Y0010_DICDI Probable serine/threonine-protein kinase
DDB_G0279405 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0279405
PE=3 SV=1
Length=695
Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 69/209 (33%), Positives = 104/209 (50%), Gaps = 25/209 (12%)
Query 900 IRDLGEGHFGKVSL-YCYDPTNDGTGEMVAVKAL------KADCG---PQHRSGWKQEID 949
+R LG+G FGKV L Y +D T + A+K K G P +EI
Sbjct 204 VRKLGKGTFGKVKLAYHHD-----THHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIA 258
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICE 1009
I++ + H +++K D E+ + +VMEY+ GS+ S LA+ + + I
Sbjct 259 IMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMS-ANETSEDLARK--YFRDIVF 315
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
G+ YLH Q IH+DL N+L++++ +VKI DFG++ + VR SP F A
Sbjct 316 GLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDD---VVRCSRGSPAFL-A 371
Query 1070 PE-CLKEYKFYYAS--DVWSFGVTLYELL 1095
PE C E + DVW+ GV+LY L+
Sbjct 372 PELCRNESQPISGKGVDVWALGVSLYCLI 400
>sp|Q2PQN9|CDK5_GLOMM Cyclin-dependent kinase 5 homolog OS=Glossina
morsitans morsitans OX=37546 GN=Cdk5 PE=2 SV=1
Length=292
Score = 76.3 bits (186), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 62/202 (31%), Positives = 100/202 (50%), Gaps = 16/202 (8%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYH 956
+K+ +GEG +G V + N T E+VA+K ++ D + S +EI +L+ L H
Sbjct 5 EKLEKIGEGTYGTV----FKGRNRETLEIVALKRVRLDEDDEGVPSSALREICLLKELKH 60
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYL 1014
++I++ EK L LV E+ L+ Y I +A F Q+ G+A+
Sbjct 61 KNIVRLYDVL--HSEKKLTLVFEHCD-QDLKKYFDSLNGDIDMAVCRSFMLQLLRGLAFC 117
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA-PECL 1073
H+ + +HRDL +N+L++ + +K+ DFGLA+A + Y + WY P+ L
Sbjct 118 HSHNVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVKCY----SAEVVTLWYRPPDVL 173
Query 1074 KEYKFYYAS-DVWSFGVTLYEL 1094
K Y S D+WS G EL
Sbjct 174 FGAKLYTTSIDMWSAGCIFAEL 195
>sp|Q9FXF2|RKF1_ARATH Probable LRR receptor-like serine/threonine-protein
kinase RFK1 OS=Arabidopsis thaliana OX=3702 GN=RKF1
PE=1 SV=1
Length=1021
Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 63/208 (30%), Positives = 98/208 (47%), Gaps = 18/208 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG V G +VAVK L + +R + EI + L H +++K
Sbjct 687 IGEGGFGAVFKGVL-----ADGRVVAVKQLSSKSRQGNRE-FLNEIGAISCLQHPNLVKL 740
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHS---IGLAQLLLFAQQICEGMAYLHAQ 1017
G C ++ + L L EY+ SL L P+H + I +G+A+LH +
Sbjct 741 HGFCVERAQ--LLLAYEYMENNSLSSALFSPKHKQIPMDWPTRFKICCGIAKGLAFLHEE 798
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
++HRD+ A N+LLD D KI DFGLA+ E + + G + + APE
Sbjct 799 SPLKFVHRDIKATNILLDKDLTPKISDFGLARLDEEEKTHISTKVAGT--IGYMAPEYAL 856
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
+ +DV+SFGV + E++ +S
Sbjct 857 WGYLTFKADVYSFGVLVLEIVAGITNSN 884
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 49/182 (27%), Positives = 79/182 (43%), Gaps = 24/182 (13%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K L F +S + H +L +HG CV + ++ EY+E+ L
Sbjct 706 VAVKQLSSKSRQGNREFLNEIGAISCLQHPNLVKLHGFCVERAQLLLAYEYMENNSLSSA 765
Query 699 LRRER-GHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTS 752
L + +PM W + + +A L++L ++ VH ++ NILL + +
Sbjct 766 LFSPKHKQIPMDWPTRFKICCGIAKGLAFLHEESPLKFVHRDIKATNILLDK-----DLT 820
Query 753 PFIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
P K+SD GL L EE+ I ++APE G L+ D + FG +L
Sbjct 821 P--KISD--FGLARLDEEEKTHISTKVAGTIGYMAPEYALWGY--LTFKADVYSFGVLVL 874
Query 806 EI 807
EI
Sbjct 875 EI 876
>sp|P83510|TNIK_MOUSE Traf2 and NCK-interacting protein kinase
OS=Mus musculus OX=10090 GN=Tnik PE=1 SV=2
Length=1323
Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 56/205 (27%), Positives = 98/205 (48%), Gaps = 22/205 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961
+G G +G+V Y + TG++ A+K + D KQEI++L+ +H +I
Sbjct 31 VGNGTYGQV----YKGRHVKTGQLAAIKVM--DVTGDEEEEIKQEINMLKKYSHHRNIAT 84
Query 962 YKGCCEDQG----EKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYL 1014
Y G + + L LVME+ GS+ D + +++ + ++I G+++L
Sbjct 85 YYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHL 144
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H IHRD+ +NVLL + VK+ DFG++ + R +W APE +
Sbjct 145 HQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---DRTVGRRNTFIGTPYWMAPEVIA 201
Query 1075 -----EYKFYYASDVWSFGVTLYEL 1094
+ + + SD+WS G+T E+
Sbjct 202 CDENPDATYDFKSDLWSLGITAIEM 226
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 55/255 (22%), Positives = 101/255 (40%), Gaps = 32/255 (13%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENI-----MVTEYVEH 692
+KV+D + + E L H ++A +G ++ P + +V E+
Sbjct 51 AAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGA 110
Query 693 GPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G + ++ +G+ + W + +++ LS+L ++H ++ G+N+LL
Sbjct 111 GSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTE------- 163
Query 752 SPFIKLSDPGVGLG---ALSREERVERIP-WLAPECLPGGANSLST---AMDKWGFGATL 804
+ +KL D GV + R P W+APE + N +T D W G T
Sbjct 164 NAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITA 223
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS------CPQLATLTSQCLTYEPTQRPS 858
+E+ +G PL P R P P + + CL +QRP+
Sbjct 224 IEMA-EGAPPLCDMHPMRALFLIPRN---PAPRLKSKKWSKKFQSFIESCLVKNHSQRPA 279
Query 859 FRTILRD-LTRLQPH 872
+++ R QP+
Sbjct 280 TEQLMKHPFIRDQPN 294
>sp|Q9FIF1|LRK21_ARATH Probable L-type lectin-domain containing
receptor kinase II.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK21
PE=2 SV=1
Length=674
Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 64/200 (32%), Positives = 96/200 (48%), Gaps = 17/200 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FGKV +G +AVK + D Q + EI + L H++++
Sbjct 361 LGAGGFGKVYKGILP-----SGTQIAVKRVYHDA-EQGMKQYVAEIASMGRLRHKNLVHL 414
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA-- 1016
G C +GE L LV +Y+P GSL DYL + + +Q + + + + YLH
Sbjct 415 LGYCRRKGE--LLLVYDYMPNGSLDDYLFHKNKLKDLTWSQRVNIIKGVASALLYLHEEW 472
Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
Q +HRD+ A N+LLD D K+GDFGLA+ G R G + + APE
Sbjct 473 EQVVLHRDIKASNILLDADLNGKLGDFGLARFHDRGVNLEATRVVG--TIGYMAPELTAM 530
Query 1076 YKFYYASDVWSFGVTLYELL 1095
+DV++FG + E++
Sbjct 531 GVTTTCTDVYAFGAFILEVV 550
Score = 62.0 bits (149), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 64/233 (27%), Positives = 103/233 (44%), Gaps = 30/233 (13%)
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVV 714
E AS M ++ H +L + G C R E ++V +Y+ +G LD +L + + W ++ +
Sbjct 399 EIAS-MGRLRHKNLVHLLGYCRRKGELLLVYDYMPNGSLDDYLFHKNKLKDLTWSQRVNI 457
Query 715 AQQLASALSYLE---NKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ +ASAL YL + ++H ++ NILL A L G + D GV L A
Sbjct 458 IKGVASALLYLHEEWEQVVLHRDIKASNILLDADLNGKLGDFGLARFHDRGVNLEA---T 514
Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-- 828
V I ++APE G +T D + FGA +LE+ G P+ +P E+ +
Sbjct 515 RVVGTIGYMAPELTAMGVT--TTCTDVYAFGAFILEVVC-GRRPVDPDAPREQVILVKWV 571
Query 829 ----RQHRLPEPSCPQLATLTSQ-----------CLTYEPTQRPSFRTILRDL 866
++ L + +L + C P RPS R IL+ L
Sbjct 572 ASCGKRDALTDTVDSKLIDFKVEEAKLLLKLGMLCSQINPENRPSMRQILQYL 624
>sp|O95382|M3K6_HUMAN Mitogen-activated protein kinase kinase
kinase 6 OS=Homo sapiens OX=9606 GN=MAP3K6 PE=1 SV=3
Length=1288
Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 65/206 (32%), Positives = 101/206 (49%), Gaps = 27/206 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ----EIDILRTLYHEH 958
LG+G +G V Y + T +A+K + P+ S + Q EI + R L H++
Sbjct 654 LGKGTYGVV----YAGRDRHTRVRIAIKEI-----PERDSRFSQPLHEEIALHRRLRHKN 704
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-----LAQLLLFAQQICEGMAY 1013
I++Y G G L++ ME VP GSL L R G + + + +QI +G+ Y
Sbjct 705 IVRYLGSASQGG--YLKIFMEEVPGGSLSSLL-RSVWGPLKDNESTISFYTRQILQGLGY 761
Query 1014 LHAQHYIHRDLAARNVLLDN-DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
LH H +HRD+ NVL++ L+KI DFG +K + E + + APE
Sbjct 762 LHDNHIVHRDIKGDNVLINTFSGLLKISDFGTSKRL---AGITPCTETFTGTLQYMAPEI 818
Query 1073 LKEYKFYY--ASDVWSFGVTLYELLT 1096
+ + Y A+D+WS G T+ E+ T
Sbjct 819 IDQGPRGYGKAADIWSLGCTVIEMAT 844
Score = 57.4 bits (137), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 58/247 (23%), Positives = 102/247 (41%), Gaps = 19/247 (8%)
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
GRDR +R+ +K + + +E +L ++ H ++ G +G + E
Sbjct 665 GRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLKIFMEE 724
Query 690 VEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
V G L LR G + + +Q+ L YL + ++VH ++ G N+L+
Sbjct 725 VPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTF-- 782
Query 748 AEGTSPFIKLSDPGVG--LGALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
S +K+SD G L ++ E + ++APE + G A D W G T
Sbjct 783 ----SGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCT 838
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCL---TYEPTQ--RPS 858
++E+ G P + F +++ P P + +Q T+EP R S
Sbjct 839 VIEMA-TGRPPFHELGSPQAAMFQVGMYKV-HPPMPSSLSAEAQAFLLRTFEPDPRLRAS 896
Query 859 FRTILRD 865
+T+L D
Sbjct 897 AQTLLGD 903
>sp|Q39086|SD17_ARATH Receptor-like serine/threonine-protein kinase
SD1-7 OS=Arabidopsis thaliana OX=3702 GN=SD17 PE=1 SV=1
Length=843
Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 65/202 (32%), Positives = 95/202 (47%), Gaps = 18/202 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V G+ +AVK L + Q + E+ ++ L H ++++
Sbjct 525 LGQGGFGIVY-----KGRLLDGKEIAVKRL-SKMSSQGTDEFMNEVRLIAKLQHINLVRL 578
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017
GCC D+GEK L+ EY+ SL +L ++ + I G+ YLH
Sbjct 579 LGCCVDKGEK--MLIYEYLENLSLDSHLFDQTRSSNLNWQKRFDIINGIARGLLYLHQDS 636
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074
IHRDL A NVLLD + KI DFG+A+ G E + Y +PE
Sbjct 637 RCRIIHRDLKASNVLLDKNMTPKISDFGMARIF--GREETEANTRRVVGTYGYMSPEYAM 694
Query 1075 EYKFYYASDVWSFGVTLYELLT 1096
+ F SDV+SFGV L E+++
Sbjct 695 DGIFSMKSDVFSFGVLLLEIIS 716
Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 57/226 (25%), Positives = 95/226 (42%), Gaps = 45/226 (20%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
+ LGQG VY+GRL +D G+E+ V K L
Sbjct 523 NKLGQGGFGIVYKGRL------------LD-----------GKEIAV--KRLSKMSSQGT 557
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW-- 710
F L++++ H +L + G CV E +++ EY+E+ LD L + + W
Sbjct 558 DEFMNEVRLIAKLQHINLVRLLGCCVDKGEKMLIYEYLENLSLDSHLFDQTRSSNLNWQK 617
Query 711 KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LG 765
+ + +A L YL + ++H ++ N+LL + +P K+SD G+ G
Sbjct 618 RFDIINGIARGLLYLHQDSRCRIIHRDLKASNVLLDK-----NMTP--KISDFGMARIFG 670
Query 766 ALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807
E R+ +++PE G S+ + D + FG LLEI
Sbjct 671 REETEANTRRVVGTYGYMSPEYAMDGIFSMKS--DVFSFGVLLLEI 714
>sp|Q9FHG4|LRKS7_ARATH Probable L-type lectin-domain containing
receptor kinase S.7 OS=Arabidopsis thaliana OX=3702 GN=LECRKS7
PE=2 SV=1
Length=681
Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 58/203 (29%), Positives = 102/203 (50%), Gaps = 18/203 (9%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R +G G FG V Y +G + AVK + + + ++ + E+ I+ L H++++
Sbjct 369 RVIGRGAFGNV----YRAMFVSSGTISAVKRSRHNS-TEGKTEFLAELSIIACLRHKNLV 423
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYL 1014
+ +G C ++GE L LV E++P GSL L + S + + L A + ++YL
Sbjct 424 QLQGWCNEKGE--LLLVYEFMPNGSLDKILYQESQTGAVALDWSHRLNIAIGLASALSYL 481
Query 1015 H---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
H Q +HRD+ N++LD + ++GDFGLA+ H+ V + + APE
Sbjct 482 HHECEQQVVHRDIKTSNIMLDINFNARLGDFGLARLTE--HDKSPVSTLTAGTMGYLAPE 539
Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094
L+ +D +S+GV + E+
Sbjct 540 YLQYGTATEKTDAFSYGVVILEV 562
>sp|Q9DGA5|CDK1_ORYCU Cyclin-dependent kinase 1 OS=Oryzias curvinotus
OX=104658 GN=cdk1 PE=2 SV=1
Length=303
Score = 76.6 bits (187), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 65/215 (30%), Positives = 109/215 (51%), Gaps = 25/215 (12%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957
KI +GEG +G V Y + TG++VA+K ++ + + S +E+ +L+ L H
Sbjct 6 KIEKIGEGTYGVV----YKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLL--FAQQICEGMAY 1013
++++ E L L+ E++ + L+ YL G + +L+ + QI EG+ +
Sbjct 62 NVVRLLDVL--MQESRLYLIFEFLSM-DLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWYAPE 1071
H + +HRDL +N+L+DN ++K+ DFGL++A VP RV +++ APE
Sbjct 119 CHRRRVLHRDLKPQNLLIDNKGVIKLADFGLSRAFGVP-----VRVYTHEVVTLWYRAPE 173
Query 1072 C-LKEYKFYYASDVWSFGVTLYELLT-----HCDS 1100
L ++ DVWS G EL T H DS
Sbjct 174 VLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDS 208
>sp|P11681|ABL_CALVI Tyrosine-protein kinase ABL (Fragment) OS=Calliphora
vicina OX=7373 GN=ABL PE=3 SV=1
Length=74
Score = 70.1 bits (170), Expect = 1e-13, Method: Composition-based stats.
Identities = 33/76 (43%), Positives = 48/76 (63%), Gaps = 2/76 (3%)
Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
R ++ LL A QI GM+YL A++YIHRDLAARN L+ +++LVK+ DFGLA+ + +
Sbjct 1 RETLDAVALLYMATQIASGMSYLEARNYIHRDLAARNCLVGDNKLVKVADFGLARLMRD- 59
Query 1052 HEYYRVREDGDSPVFW 1067
+ Y P+ W
Sbjct 60 -DTYTAHAGAKFPIKW 74
Score = 37.7 bits (86), Expect = 0.039, Method: Composition-based stats.
Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 9/60 (15%)
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771
+ +A Q+AS +SYLE +N +H ++ RN L+ G + +K++D GL L R++
Sbjct 10 LYMATQIASGMSYLEARNYIHRDLAARNCLV-------GDNKLVKVAD--FGLARLMRDD 60
>sp|Q9IA88|SIK2_CHICK Serine/threonine-protein kinase SIK2 OS=Gallus
gallus OX=9031 GN=SIK2 PE=2 SV=1
Length=798
Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 66/223 (30%), Positives = 101/223 (45%), Gaps = 25/223 (11%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQH 940
P A+ P + R LG+G+F V L + T VA+K + K P +
Sbjct 11 PAPSAAQPRPLRVGFYDIERTLGKGNFAVVKLARHRVTKT----QVAIKIIDKTRLDPSN 66
Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQ 999
+E+ I++ L H HIIK E + L +V E+ G + D+L + + ++
Sbjct 67 LEKIYREVQIMKLLNHPHIIKLYQVMETK--DMLYIVTEFAKNGEMFDHLTSNGHLSESE 124
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
QI + Y H+ H +HRDL N+LLD + +K+ DFG +Y+ E
Sbjct 125 ARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDANMNIKLADFGFGN-------FYKSGE 177
Query 1060 D-----GDSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELL 1095
G P + APE KEY+ + D+WS GV LY L+
Sbjct 178 PLSTWCGSPP--YAAPEVFEGKEYEGPHL-DIWSLGVVLYVLV 217
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 58/243 (24%), Positives = 102/243 (42%), Gaps = 24/243 (10%)
Query 630 GRDRGQELRVVLKVLDPSHHDIAL--AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
R R + +V +K++D + D + Y +M ++H H+ ++ V +VT
Sbjct 43 ARHRVTKTQVAIKIIDKTRLDPSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVT 102
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
E+ ++G + L GH+ + Q+ SA+ Y + ++VH ++ N+LL
Sbjct 103 EFAKNGEMFDHLT-SNGHLSESEARKKFWQILSAVEYCHSHHIVHRDLKTENLLL----- 156
Query 748 AEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+ IKL+D G G S E P+ APE G +D W G L
Sbjct 157 --DANMNIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYE-GPHLDIWSLGVVL 213
Query 805 -LEIC----FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859
+ +C FDG P+ ++ + + R+P TL + L +PT+R +
Sbjct 214 YVLVCGSLPFDG-----PNLPTLRQRVLEGRFRIPYFMSEDCETLIRRMLVVDPTKRITI 268
Query 860 RTI 862
I
Sbjct 269 SQI 271
>sp|O49318|Y2317_ARATH Probable leucine-rich repeat receptor-like
protein kinase At2g33170 OS=Arabidopsis thaliana OX=3702
GN=At2g33170 PE=2 SV=1
Length=1124
Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 60/188 (32%), Positives = 89/188 (47%), Gaps = 18/188 (10%)
Query 923 TGEMVAVKALKADCGPQHRSG------WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976
+G+ +AVK L+++ + + ++ EI L + H +I++ C QG S L
Sbjct 840 SGKTIAVKKLESNREGNNNNSNNTDNSFRAEILTLGKIRHRNIVRLYSFCYHQGSNSNLL 899
Query 977 VMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVL 1030
+ EY+ GSL + L HS+ A EG+AYLH IHRD+ + N+L
Sbjct 900 LYEYMSRGSLGELLHGGKSHSMDWPTRFAIALGAAEGLAYLHHDCKPRIIHRDIKSNNIL 959
Query 1031 LDNDRLVKIGDFGLAKAV--PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
+D + +GDFGLAK + P V + APE K D++SFG
Sbjct 960 IDENFEAHVGDFGLAKVIDMPLSKSVSAVA----GSYGYIAPEYAYTMKVTEKCDIYSFG 1015
Query 1089 VTLYELLT 1096
V L ELLT
Sbjct 1016 VVLLELLT 1023
>sp|Q9FIF0|LRK22_ARATH Putative L-type lectin-domain containing
receptor kinase II.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK22
PE=3 SV=3
Length=694
Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 63/208 (30%), Positives = 101/208 (49%), Gaps = 17/208 (8%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R ++ R LG G FGKV +G +AVK + + Q + EI + L
Sbjct 373 RGFRENRLLGAGGFGKVY-----KGELPSGTQIAVKRVYHNA-EQGMKQYAAEIASMGRL 426
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEG 1010
H+++++ G C +GE L LV +Y+P GSL DYL + + +Q + + +
Sbjct 427 RHKNLVQLLGYCRRKGE--LLLVYDYMPNGSLDDYLFNKNKLKDLTWSQRVNIIKGVASA 484
Query 1011 MAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH Q +HRD+ A N+LLD D ++GDFGLA+ G R G + +
Sbjct 485 LLYLHEEWEQVVLHRDIKASNILLDADLNGRLGDFGLARFHDRGENLQATRVVG--TIGY 542
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095
APE +D+++FG + E++
Sbjct 543 MAPELTAMGVATTKTDIYAFGSFILEVV 570
Score = 59.7 bits (143), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 62/233 (27%), Positives = 104/233 (45%), Gaps = 30/233 (13%)
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVV 714
E AS M ++ H +L + G C R E ++V +Y+ +G LD +L + + W ++ +
Sbjct 419 EIAS-MGRLRHKNLVQLLGYCRRKGELLLVYDYMPNGSLDDYLFNKNKLKDLTWSQRVNI 477
Query 715 AQQLASALSYLE---NKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ +ASAL YL + ++H ++ NILL A L G + D G L A
Sbjct 478 IKGVASALLYLHEEWEQVVLHRDIKASNILLDADLNGRLGDFGLARFHDRGENLQA---T 534
Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-- 828
V I ++APE G +T D + FG+ +LE+ G P++ P E+ H +
Sbjct 535 RVVGTIGYMAPELTAMGV--ATTKTDIYAFGSFILEVVC-GRRPVEPDRPPEQMHLLKWV 591
Query 829 ----RQHRLPEPSCPQLATLTSQ-----------CLTYEPTQRPSFRTILRDL 866
++ L + +L ++ C P RPS R I++ L
Sbjct 592 ATCGKRDTLMDVVDSKLGDFKAKEAKLLLKLGMLCSQSNPESRPSMRHIIQYL 644
>sp|P0C5D6|SAPK3_ORYSJ Serine/threonine-protein kinase SAPK3 OS=Oryza
sativa subsp. japonica OX=39947 GN=SAPK3 PE=1 SV=1
Length=334
Score = 77.0 bits (188), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 73/212 (34%), Positives = 107/212 (50%), Gaps = 23/212 (11%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
+RY + +++LG G+FG L + + E+VAVK ++ G + ++EI
Sbjct 1 MEERY-EALKELGAGNFGVARLV----RDKRSKELVAVKYIER--GKKIDENVQREIINH 53
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQIC 1008
R+L H +II++K C L +VMEY G L + + R S A+ F QQ+
Sbjct 54 RSLRHPNIIRFKEVC--LTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARY--FFQQLI 109
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRL--VKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G++Y H+ HRDL N LLD VKI DFG +K+ + + + +P
Sbjct 110 SGVSYCHSLEICHRDLKLENTLLDGSPTPRVKICDFGYSKS---ALLHSKPKSTVGTPA- 165
Query 1067 WYAPECL--KEYKFYYASDVWSFGVTLYELLT 1096
+ APE L KEY A DVWS GVTLY +L
Sbjct 166 YIAPEVLSRKEYDGKVA-DVWSCGVTLYVMLV 196
>sp|A2ZAB5|SAPK3_ORYSI Serine/threonine-protein kinase SAPK3 OS=Oryza
sativa subsp. indica OX=39946 GN=SAPK3 PE=1 SV=2
Length=334
Score = 77.0 bits (188), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 73/212 (34%), Positives = 107/212 (50%), Gaps = 23/212 (11%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
+RY + +++LG G+FG L + + E+VAVK ++ G + ++EI
Sbjct 1 MEERY-EALKELGAGNFGVARLV----RDKRSKELVAVKYIER--GKKIDENVQREIINH 53
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQIC 1008
R+L H +II++K C L +VMEY G L + + R S A+ F QQ+
Sbjct 54 RSLRHPNIIRFKEVC--LTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARY--FFQQLI 109
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRL--VKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G++Y H+ HRDL N LLD VKI DFG +K+ + + + +P
Sbjct 110 SGVSYCHSLEICHRDLKLENTLLDGSPTPRVKICDFGYSKS---ALLHSKPKSTVGTPA- 165
Query 1067 WYAPECL--KEYKFYYASDVWSFGVTLYELLT 1096
+ APE L KEY A DVWS GVTLY +L
Sbjct 166 YIAPEVLSRKEYDGKVA-DVWSCGVTLYVMLV 196
>sp|Q9XEC7|CRK37_ARATH Cysteine-rich receptor-like protein kinase
37 OS=Arabidopsis thaliana OX=3702 GN=CRK37 PE=3 SV=1
Length=646
Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 65/205 (32%), Positives = 97/205 (47%), Gaps = 24/205 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V +G+ +AVK L+ G Q +K E+ +L L H +++K
Sbjct 351 LGQGGFGSVYKGILP-----SGQEIAVKRLRKGSG-QGGMEFKNEVLLLTRLQHRNLVKL 404
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017
G C ++ E+ L V E+VP SL ++ R + + + G+ YLH
Sbjct 405 LGFCNEKDEEIL--VYEFVPNSSLDHFIFDEEKRRVLTWDVRYTIIEGVARGLLYLHEDS 462
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAV----PEGHEYYRVREDGDSPVFWYAPE 1071
IHRDL A N+LLD + K+ DFG+A+ G V G + APE
Sbjct 463 QLRIIHRDLKASNILLDAEMNPKVADFGMARLFDMDETRGQTSRVVGTYG-----YMAPE 517
Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096
+F SDV+SFGV L E+++
Sbjct 518 YATYGQFSTKSDVYSFGVMLLEMIS 542
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 49/180 (27%), Positives = 78/180 (43%), Gaps = 12/180 (7%)
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
GQE+ V K L + F L++++ H +L + G C E I+V E+V +
Sbjct 367 GQEIAV--KRLRKGSGQGGMEFKNEVLLLTRLQHRNLVKLLGFCNEKDEEILVYEFVPNS 424
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILL-ARLGL 747
LD ++ E + W + + + +A L YL + ++H ++ NILL A +
Sbjct 425 SLDHFIFDEEKRRVLTWDVRYTIIEGVARGLLYLHEDSQLRIIHRDLKASNILLDAEMNP 484
Query 748 AEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+L D G SR V ++APE G ST D + FG LLE+
Sbjct 485 KVADFGMARLFDMDETRGQTSRV--VGTYGYMAPEYATYG--QFSTKSDVYSFGVMLLEM 540
>sp|P39951|CDK1_RAT Cyclin-dependent kinase 1 OS=Rattus norvegicus
OX=10116 GN=Cdk1 PE=1 SV=1
Length=297
Score = 76.3 bits (186), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 62/233 (27%), Positives = 110/233 (47%), Gaps = 23/233 (10%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957
KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L H
Sbjct 6 KIEKIGEGTYGVV----YKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAY 1013
+I+ + + L L+ E++ + L+ YL P + + + + QI +G+ +
Sbjct 62 NIVSLQDVL--MQDSRLYLIFEFLSM-DLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVF 118
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072
H++ +HRDL +N+L+D+ +K+ DFGLA+A Y + WY +PE
Sbjct 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYT----HEVVTLWYRSPEV 174
Query 1073 -LKEYKFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQM 1119
L ++ D+WS G EL T H DS + +G ++
Sbjct 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV 227
>sp|Q9SN43|CIPKC_ARATH CBL-interacting serine/threonine-protein
kinase 12 OS=Arabidopsis thaliana OX=3702 GN=CIPK12 PE=1 SV=1
Length=489
Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 65/203 (32%), Positives = 99/203 (49%), Gaps = 24/203 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYHEH 958
LG G F KV Y N T E VA+K + D + G K+EI ILR + H +
Sbjct 32 LGHGTFAKV----YLARNVKTNESVAIKVI--DKEKVLKGGLIAHIKREISILRRVRHPN 85
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I++ + + + VMEYV G L + + + + + QQ+ + + HA+
Sbjct 86 IVQLFEVMATKAK--IYFVMEYVRGGELFNKVAKGRLKEEVARKYFQQLISAVTFCHARG 143
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WYAPECL 1073
HRDL N+LLD + +K+ DFGL+ AV + ++R+DG F + APE L
Sbjct 144 VYHRDLKPENLLLDENGNLKVSDFGLS-AVSD-----QIRQDGLFHTFCGTPAYVAPEVL 197
Query 1074 KEYKFYYAS-DVWSFGVTLYELL 1095
+ A D+WS GV L+ L+
Sbjct 198 ARKGYDAAKVDIWSCGVILFVLM 220
Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 53/215 (25%), Positives = 93/215 (43%), Gaps = 22/215 (10%)
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719
S++ +V H ++ + V + V EYV G L + + R +A K QQL
Sbjct 76 SILRRVRHPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAKGRLKEEVARKYF--QQLI 133
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776
SA+++ + + H ++ N+LL G +K+SD GL A+S + R + +
Sbjct 134 SAVTFCHARGVYHRDLKPENLLLDENG-------NLKVSD--FGLSAVSDQIRQDGLFHT 184
Query 777 -----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP-SEKEHFYQRQ 830
++APE L + +D W G L + G P R+ + + Y+ +
Sbjct 185 FCGTPAYVAPEVLARKGYD-AAKVDIWSCGVILF-VLMAGYLPFHDRNVMAMYKKIYRGE 242
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
R P +L L S+ L P +R +F I+ +
Sbjct 243 FRCPRWFSTELTRLLSKLLETNPEKRFTFPEIMEN 277
>sp|Q5BBL3|STE20_EMENI Serine/threonine-protein kinase ste20 OS=Emericella
nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46
/ NRRL 194 / M139) OX=227321 GN=ste20 PE=3 SV=1
Length=848
Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 53/208 (25%), Positives = 98/208 (47%), Gaps = 14/208 (7%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DPT + + +G+G G V Y+ T VA+K + D P+ + E
Sbjct 562 DPTKLYY----NLNKIGQGASGGV-FTAYE---QHTNNCVAIKQMNLDLQPK-KDLIINE 612
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007
I +++ H++I+ + + L +VMEY+ GSL D + + + Q+ ++
Sbjct 613 ILVMKDSKHKNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMSEPQIAAVCRET 670
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
G+ +LH++ IHRD+ + N+LL D +K+ DFG + ++ R +W
Sbjct 671 LNGLQHLHSKGVIHRDIKSDNILLSLDGNIKLTDFGFCAQI---NDSQNKRNTMVGTPYW 727
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095
APE + ++ D+WS G+ E++
Sbjct 728 MAPEVVTRKEYGRKVDIWSLGIMAIEMI 755
Score = 37.7 bits (86), Expect = 0.72, Method: Compositional matrix adjust.
Identities = 42/165 (25%), Positives = 69/165 (42%), Gaps = 18/165 (11%)
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719
+M H ++ + G + +V EY+E G L DV +A V ++
Sbjct 615 VMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVVTFNIMSEPQIA---AVCRETL 671
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERVER 775
+ L +L +K ++H ++ NILL+ G IKL+D G + R V
Sbjct 672 NGLQHLHSKGVIHRDIKSDNILLSLDG-------NIKLTDFGFCAQINDSQNKRNTMVGT 724
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
W+APE + +D W G +E+ +GE P + SP
Sbjct 725 PYWMAPEVV--TRKEYGRKVDIWSLGIMAIEM-IEGEPPYLTESP 766
>sp|P11440|CDK1_MOUSE Cyclin-dependent kinase 1 OS=Mus musculus
OX=10090 GN=Cdk1 PE=1 SV=3
Length=297
Score = 76.3 bits (186), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 62/233 (27%), Positives = 110/233 (47%), Gaps = 23/233 (10%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957
KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L H
Sbjct 6 KIEKIGEGTYGVV----YKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAY 1013
+I+ + + L L+ E++ + L+ YL P + + + + QI +G+ +
Sbjct 62 NIVSLQDVL--MQDSRLYLIFEFLSM-DLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVF 118
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072
H++ +HRDL +N+L+D+ +K+ DFGLA+A Y + WY +PE
Sbjct 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYT----HEVVTLWYRSPEV 174
Query 1073 -LKEYKFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQM 1119
L ++ D+WS G EL T H DS + +G ++
Sbjct 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV 227
>sp|Q9ZVM9|Y1461_ARATH Probable serine/threonine-protein kinase
At1g54610 OS=Arabidopsis thaliana OX=3702 GN=At1g54610 PE=1
SV=1
Length=572
Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 61/205 (30%), Positives = 99/205 (48%), Gaps = 13/205 (6%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLY 955
+KI +G+G + V Y + TG++VA+K ++ D P+ +EI +LR L
Sbjct 118 FEKIDKIGQGTYSNV----YKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRLD 173
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013
H +++K +G + SL LV +Y+ L L P +++ +Q+ G+ +
Sbjct 174 HPNVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASS-PVVKFSESEVKCLMRQLISGLEH 232
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072
H++ +HRD+ N+L+D+ ++KI DFGLA H+ WY APE
Sbjct 233 CHSRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRPMTSR---VVTLWYRAPEL 289
Query 1073 LKEYKFY-YASDVWSFGVTLYELLT 1096
L Y D+WS G L ELL
Sbjct 290 LLGATDYGVGIDLWSAGCILAELLA 314
>sp|Q7XUF4|CDKG2_ORYSJ Cyclin-dependent kinase G-2 OS=Oryza sativa
subsp. japonica OX=39947 GN=CDKG-2 PE=2 SV=2
Length=710
Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 66/209 (32%), Positives = 101/209 (48%), Gaps = 22/209 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILR 952
+++ + EG +G V Y + TGE+VA+K +K + + R G+ +EI+IL
Sbjct 365 FERLNKINEGTYGVV----YRARDKKTGEIVALKKVKME---KEREGFPLTSLREINILL 417
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQICE 1009
+ +H I+ K S+ +VMEY+ G + +S + L+ Q+ E
Sbjct 418 SFHHPSIVDVKEVVVGSSLDSIFMVMEYMEHDLKGVMEAMKQPYSQSEVKCLML--QLLE 475
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068
G+ YLH +HRDL N+LL+N +KI DFGL++ + Y WY
Sbjct 476 GVKYLHDNWVLHRDLKTSNLLLNNRGELKICDFGLSRQYGSPLKPYTQL----VVTLWYR 531
Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLT 1096
APE L K Y A D+WS G + ELL
Sbjct 532 APELLLGTKEYSTAIDMWSVGCIMAELLA 560
>sp|A2XUW1|CDKG2_ORYSI Cyclin-dependent kinase G-2 OS=Oryza sativa
subsp. indica OX=39946 GN=CDKG-2 PE=3 SV=1
Length=710
Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 66/209 (32%), Positives = 101/209 (48%), Gaps = 22/209 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILR 952
+++ + EG +G V Y + TGE+VA+K +K + + R G+ +EI+IL
Sbjct 365 FERLNKINEGTYGVV----YRARDKKTGEIVALKKVKME---KEREGFPLTSLREINILL 417
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQICE 1009
+ +H I+ K S+ +VMEY+ G + +S + L+ Q+ E
Sbjct 418 SFHHPSIVDVKEVVVGSSLDSIFMVMEYMEHDLKGVMEAMKQPYSQSEVKCLML--QLLE 475
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068
G+ YLH +HRDL N+LL+N +KI DFGL++ + Y WY
Sbjct 476 GVKYLHDNWVLHRDLKTSNLLLNNRGELKICDFGLSRQYGSPLKPYTQL----VVTLWYR 531
Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLT 1096
APE L K Y A D+WS G + ELL
Sbjct 532 APELLLGTKEYSTAIDMWSVGCIMAELLA 560
>sp|Q940A2|P2C31_ARATH Protein kinase and PP2C-like domain-containing
protein OS=Arabidopsis thaliana OX=3702 GN=At2g40860/At2g40870
PE=2 SV=1
Length=658
Score = 79.0 bits (193), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 55/206 (27%), Positives = 97/206 (47%), Gaps = 28/206 (14%)
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY- 1054
+ Q+LL + + + YLH +HRD+ NVLLD + DFGLA+ E
Sbjct 122 SIDQVLLITLHLAKALQYLHNNGIVHRDVKPANVLLDEKFFPYLADFGLAEYKKNLREVN 181
Query 1055 -YRVREDGD-----------SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT----HC 1098
R G + + APE L++ + +D++SFG+ + ELLT +
Sbjct 182 LQNWRSSGKPTGGFHKKNMVGTLIYMAPEILRKDMYTEKADIYSFGILINELLTGVVPYT 241
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTE-----LLERGERLPRPDKCPCEVYHLMKNCWE 1153
D + + + Q+TV ++ L E G LP+ + L++NCWE
Sbjct 242 DRRAEAQAHTVLEMNYTEQQLTVAIVSSGLRPALAEIGLHLPK------SLLSLIQNCWE 295
Query 1154 TEASFRPTFENLIPILKTVHEKYQGQ 1179
++ S RP+ +N++ L+++ E+ +G+
Sbjct 296 SDPSKRPSSDNVVLELESIWEQVRGK 321
Score = 47.4 bits (111), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 55/248 (22%), Positives = 97/248 (39%), Gaps = 36/248 (15%)
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F+ L ++H +A + + P + ++ E G L L E + +++
Sbjct 70 FHRNLQLSCNLNHPGVAKLLAAHAKPPNYMFFFDFYESGTLAEKLHVEEWSPSIDQVLLI 129
Query 715 AQQLASALSYLENKNLVHGNVCGRNIL--------LARLGLAEGTSPFIKLS-----DPG 761
LA AL YL N +VH +V N+L LA GLAE +++ G
Sbjct 130 TLHLAKALQYLHNNGIVHRDVKPANVLLDEKFFPYLADFGLAEYKKNLREVNLQNWRSSG 189
Query 762 VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
G ++ V + ++APE L + + D + FG + E+ G P R
Sbjct 190 KPTGGFHKKNMVGTLIYMAPEILR--KDMYTEKADIYSFGILINEL-LTGVVPYTDRRAE 246
Query 822 EKEH------FYQRQHRLPEPSC---PQLA-----------TLTSQCLTYEPTQRPSFRT 861
+ H + ++Q + S P LA +L C +P++RPS
Sbjct 247 AQAHTVLEMNYTEQQLTVAIVSSGLRPALAEIGLHLPKSLLSLIQNCWESDPSKRPSSDN 306
Query 862 ILRDLTRL 869
++ +L +
Sbjct 307 VVLELESI 314
>sp|O74536|SNF1_SCHPO SNF1-like protein kinase ssp2 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=ssp2
PE=1 SV=1
Length=576
Score = 78.6 bits (192), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 72/216 (33%), Positives = 106/216 (49%), Gaps = 20/216 (9%)
Query 889 PTVFHKRYLKK--IRD-LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
P KR++ IR+ LGEG FGKV L T+ T + VA+K + + +
Sbjct 23 PEAISKRHIGPYIIRETLGEGSFGKVKL----ATHYKTQQKVALKFISRQLLKKSDMHMR 78
Query 946 --QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLL 1002
+EI L+ L H HIIK + + +V+EY G L DY+ + + +
Sbjct 79 VEREISYLKLLRHPHIIKLYDVITTPTD--IVMVIEYAG-GELFDYIVEKKRMTEDEGRR 135
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
F QQI + Y H +HRDL N+LLD++ VKI DFGL+ + +G+ ++
Sbjct 136 FFQQIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGN---FLKTSCG 192
Query 1063 SPVFWYAPECLKEYKFYYA--SDVWSFGVTLYELLT 1096
SP + APE + K Y DVWS G+ LY +L
Sbjct 193 SPNYA-APEVING-KLYAGPEVDVWSCGIVLYVMLV 226
Score = 35.4 bits (80), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 44/222 (20%), Positives = 87/222 (39%), Gaps = 19/222 (9%)
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
D+ + S + + H H+ ++ V + +MV EY D + ++R
Sbjct 74 DMHMRVEREISYLKLLRHPHIIKLYDVITTPTDIVMVIEYAGGELFDYIVEKKRMTEDEG 133
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+ QQ+ A+ Y +VH ++ N+LL + +K++D GL +
Sbjct 134 RRFF--QQIICAIEYCHRHKIVHRDLKPENLLL-------DDNLNVKIAD--FGLSNIMT 182
Query 770 EERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR-SPSEK 823
+ + + APE + G + +D W G +L + G P P+
Sbjct 183 DGNFLKTSCGSPNYAAPEVINGKLYA-GPEVDVWSCG-IVLYVMLVGRLPFDDEFIPNLF 240
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ + +P+ P +L + + +P QR + + I RD
Sbjct 241 KKVNSCVYVMPDFLSPGAQSLIRRMIVADPMQRITIQEIRRD 282
>sp|Q8H1D6|RBK1_ARATH Receptor-like cytosolic serine/threonine-protein
kinase RBK1 OS=Arabidopsis thaliana OX=3702 GN=RBK1
PE=1 SV=1
Length=467
Score = 78.2 bits (191), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 59/181 (33%), Positives = 91/181 (50%), Gaps = 11/181 (6%)
Query 923 TGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
GE VA+K L + + S + E+ I+ + H + + +G D+G L V+EY
Sbjct 174 NGETVAIKKLMSHAKEEEERVSDFLSELGIIAHVNHPNAARLRGFSSDRG---LHFVLEY 230
Query 981 VPLGSLRDYLPRHSIGLAQLLLF--AQQICEGMAYLHA---QHYIHRDLAARNVLLDNDR 1035
P GSL L L + + A I +G++YLH + IHRD+ A N+LL++D
Sbjct 231 APYGSLASMLFGSEECLEWKIRYKVALGIADGLSYLHNACPRRIIHRDIKASNILLNHDY 290
Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+I DFGLAK +PE ++ V + + APE DV++FGV L E++
Sbjct 291 EAQISDFGLAKWLPENWPHHVVFPI-EGTFGYLAPEYFMHGIVDEKIDVFAFGVLLLEII 349
Query 1096 T 1096
T
Sbjct 350 T 350
>sp|Q6ICW6|WNK11_ARATH Probable serine/threonine-protein kinase
WNK11 OS=Arabidopsis thaliana OX=3702 GN=WNK11 PE=2 SV=1
Length=314
Score = 76.6 bits (187), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 69/226 (31%), Positives = 106/226 (47%), Gaps = 25/226 (11%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC---GPQHRSGW 944
DPT + RY + LG G KV Y + G VA +K C P
Sbjct 25 DPTGRYGRYGEL---LGSGAVKKV----YRAFDQEEGIEVAWNQVKLRCFSDDPAMTERL 77
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLF 1003
E+ +L+ L + +II D+ +L + E G+LR+Y +H + + L +
Sbjct 78 YSEVRLLKNLKNSNIITLYKVWRDERNNTLNFITEICTSGNLREYRKKHRHVSMRALKKW 137
Query 1004 AQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
++QI +G+ YLH IHRDL N+ ++ N VKIGD GLA V + H + +
Sbjct 138 SKQILKGLDYLHTHDPCIIHRDLNCSNIFVNGNIGQVKIGDLGLAAIVGKNHLAHSIL-- 195
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL------THCDS 1100
+P F APE L E + D++S+G+ + EL+ + CDS
Sbjct 196 -GTPEFM-APE-LYEENYTEMVDIYSYGMCVLELVSLEIPYSECDS 238
Lambda K H a alpha
0.321 0.138 0.435 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 140973851148
Results from round 2
Query= sp|P29597|TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2
OS=Homo sapiens OX=9606 GN=TYK2 PE=1 SV=3
Length=1187
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|P29597|TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 OS... 1630 0.0
sp|Q9R117|TYK2_MOUSE Non-receptor tyrosine-protein kinase TYK2 OS... 1498 0.0
sp|O12990|JAK1_DANRE Tyrosine-protein kinase JAK1 OS=Danio rerio ... 1224 0.0
sp|P23458|JAK1_HUMAN Tyrosine-protein kinase JAK1 OS=Homo sapiens... 1219 0.0
sp|P52332|JAK1_MOUSE Tyrosine-protein kinase JAK1 OS=Mus musculus... 1219 0.0
sp|Q75R65|JAK2_CHICK Tyrosine-protein kinase JAK2 OS=Gallus gallu... 1172 0.0
sp|Q09178|JAK1_CYPCA Tyrosine-protein kinase JAK1 OS=Cyprinus car... 1164 0.0
sp|Q5RB23|JAK2_PONAB Tyrosine-protein kinase JAK2 OS=Pongo abelii... 1147 0.0
sp|O60674|JAK2_HUMAN Tyrosine-protein kinase JAK2 OS=Homo sapiens... 1145 0.0
sp|Q62689|JAK2_RAT Tyrosine-protein kinase JAK2 OS=Rattus norvegi... 1139 0.0
sp|O19064|JAK2_PIG Tyrosine-protein kinase JAK2 OS=Sus scrofa OX=... 1138 0.0
sp|Q62120|JAK2_MOUSE Tyrosine-protein kinase JAK2 OS=Mus musculus... 1131 0.0
sp|Q62137|JAK3_MOUSE Tyrosine-protein kinase JAK3 OS=Mus musculus... 1036 0.0
sp|P52333|JAK3_HUMAN Tyrosine-protein kinase JAK3 OS=Homo sapiens... 1036 0.0
sp|Q63272|JAK3_RAT Tyrosine-protein kinase JAK3 OS=Rattus norvegi... 1025 0.0
sp|Q24592|JAK_DROME Tyrosine-protein kinase hopscotch OS=Drosophi... 416 1e-124
sp|P42688|SRK2_SPOLA Tyrosine-protein kinase SRK2 (Fragment) OS=S... 323 3e-99
sp|P42690|SRK4_SPOLA Tyrosine-protein kinase isoform SRK4 OS=Spon... 323 1e-97
sp|Q54I36|PYK3_DICDI Dual specificity protein kinase pyk3 OS=Dict... 342 4e-97
sp|P42686|SRK1_SPOLA Tyrosine-protein kinase isoform SRK1 OS=Spon... 320 1e-96
sp|P18652|KS6AA_CHICK Ribosomal protein S6 kinase 2 alpha OS=Gall... 326 1e-95
sp|Q9UK32|KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 OS=Homo... 325 1e-95
sp|Q62662|FRK_RAT Tyrosine-protein kinase FRK OS=Rattus norvegicu... 318 1e-95
sp|O45539|SRC2_CAEEL Tyrosine protein-kinase src-2 OS=Caenorhabdi... 318 1e-95
sp|P00528|SRC64_DROME Tyrosine-protein kinase Src64B OS=Drosophil... 319 1e-95
sp|Q552C6|ZAK2_DICDI Dual specificity protein kinase zak2 OS=Dict... 320 8e-95
sp|P42685|FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo sapiens O... 314 2e-94
sp|Q922K9|FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus musculus O... 315 3e-94
sp|P27446|FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiphophorus he... 312 3e-93
sp|Q9V9J3|SRC42_DROME Tyrosine-protein kinase Src42A OS=Drosophil... 311 8e-93
sp|Q02977|YRK_CHICK Proto-oncogene tyrosine-protein kinase Yrk OS... 311 8e-93
sp|Q6EWH2|FYNA_DANRE Tyrosine-protein kinase fyna OS=Danio rerio ... 310 2e-92
sp|P13406|FYN_XENLA Tyrosine-protein kinase Fyn OS=Xenopus laevis... 310 2e-92
sp|P10936|YES_XENLA Tyrosine-protein kinase Yes OS=Xenopus laevis... 308 1e-91
sp|P09324|YES_CHICK Tyrosine-protein kinase Yes OS=Gallus gallus ... 308 2e-91
sp|P13116|SRC2_XENLA Tyrosine-protein kinase Src-2 OS=Xenopus lae... 307 2e-91
sp|P00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src OS... 307 2e-91
sp|P39688|FYN_MOUSE Tyrosine-protein kinase Fyn OS=Mus musculus O... 307 2e-91
sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo sapiens O... 307 3e-91
sp|Q62844|FYN_RAT Tyrosine-protein kinase Fyn OS=Rattus norvegicu... 307 3e-91
sp|A1Y2K1|FYN_PIG Tyrosine-protein kinase Fyn OS=Sus scrofa OX=98... 307 3e-91
sp|A0JNB0|FYN_BOVIN Tyrosine-protein kinase Fyn OS=Bos taurus OX=... 307 3e-91
sp|P14084|SRC_AVISS Tyrosine-protein kinase transforming protein ... 308 3e-91
sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src OS... 306 4e-91
sp|Q9TTY2|FER_CANLF Tyrosine-protein kinase Fer OS=Canis lupus fa... 315 4e-91
sp|P70451|FER_MOUSE Tyrosine-protein kinase Fer OS=Mus musculus O... 315 5e-91
sp|P14085|SRC_AVIST Tyrosine-protein kinase transforming protein ... 307 6e-91
sp|P00525|SRC_AVISR Tyrosine-protein kinase transforming protein ... 305 7e-91
sp|P63185|SRC_RSVSE Tyrosine-protein kinase transforming protein ... 305 1e-90
sp|P15054|SRC_AVIS2 Tyrosine-protein kinase transforming protein ... 307 1e-90
sp|P09760|FER_RAT Tyrosine-protein kinase Fer OS=Rattus norvegicu... 313 1e-90
sp|P05480|SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src OS... 305 2e-90
sp|Q9WUD9|SRC_RAT Proto-oncogene tyrosine-protein kinase Src OS=R... 305 2e-90
sp|P07947|YES_HUMAN Tyrosine-protein kinase Yes OS=Homo sapiens O... 305 3e-90
sp|Q05876|FYN_CHICK Tyrosine-protein kinase Fyn OS=Gallus gallus ... 304 3e-90
sp|F1RDG9|FYNB_DANRE Tyrosine-protein kinase fynb OS=Danio rerio ... 305 3e-90
sp|P31693|SRC_RSVPA Tyrosine-protein kinase transforming protein ... 303 3e-90
sp|P00524|SRC_RSVSA Tyrosine-protein kinase transforming protein ... 303 5e-90
sp|P17713|STK_HYDVU Tyrosine-protein kinase STK OS=Hydra vulgaris... 302 6e-90
sp|A1A5H8|YES_DANRE Tyrosine-protein kinase yes OS=Danio rerio OX... 303 7e-90
sp|P00527|YES_AVISY Tyrosine-protein kinase transforming protein ... 303 7e-90
sp|P27447|YES_XIPHE Tyrosine-protein kinase Yes OS=Xiphophorus he... 303 9e-90
sp|Q04736|YES_MOUSE Tyrosine-protein kinase Yes OS=Mus musculus O... 303 1e-89
sp|Q1JPZ3|SRC_DANRE Proto-oncogene tyrosine-protein kinase Src OS... 302 1e-89
sp|P13115|SRC1_XENLA Tyrosine-protein kinase Src-1 OS=Xenopus lae... 302 2e-89
sp|Q6P6U0|FGR_RAT Tyrosine-protein kinase Fgr OS=Rattus norvegicu... 301 3e-89
sp|F1LM93|YES_RAT Tyrosine-protein kinase Yes OS=Rattus norvegicu... 301 6e-89
sp|P14234|FGR_MOUSE Tyrosine-protein kinase Fgr OS=Mus musculus O... 299 1e-88
sp|P10447|ABL_FSVHY Tyrosine-protein kinase transforming protein ... 296 2e-88
sp|P00526|SRC_RSVP Tyrosine-protein kinase transforming protein S... 299 2e-88
sp|P25020|SRC_RSVH1 Tyrosine-protein kinase transforming protein ... 298 3e-88
sp|P16591|FER_HUMAN Tyrosine-protein kinase Fer OS=Homo sapiens O... 306 4e-88
sp|Q28923|YES_CANLF Tyrosine-protein kinase Yes OS=Canis lupus fa... 298 6e-88
sp|O13148|EPA4A_DANRE Ephrin type-A receptor 4a (Fragment) OS=Dan... 288 1e-87
sp|G5EE56|SRC1_CAEEL Tyrosine protein-kinase src-1 OS=Caenorhabdi... 297 1e-87
sp|P00521|ABL_MLVAB Tyrosine-protein kinase transforming protein ... 303 2e-87
sp|P09769|FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo sapiens O... 294 2e-86
sp|P54755|EPHA5_CHICK Ephrin type-A receptor 5 OS=Gallus gallus O... 305 4e-86
sp|Q60629|EPHA5_MOUSE Ephrin type-A receptor 5 OS=Mus musculus OX... 302 4e-86
sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens O... 292 5e-86
sp|P25911|LYN_MOUSE Tyrosine-protein kinase Lyn OS=Mus musculus O... 292 5e-86
sp|P00543|FES_FSVST Tyrosine-protein kinase transforming protein ... 290 6e-86
sp|Q07014|LYN_RAT Tyrosine-protein kinase Lyn OS=Rattus norvegicu... 291 7e-86
sp|Q95KR7|LCK_SAISC Proto-oncogene tyrosine-protein kinase LCK OS... 291 1e-85
sp|P42683|LCK_CHICK Proto-oncogene tyrosine-protein kinase LCK OS... 291 1e-85
sp|P42689|SRK3_SPOLA Tyrosine-protein kinase SRK3 (Fragment) OS=S... 283 3e-85
sp|Q01621|LCK_RAT Proto-oncogene tyrosine-protein kinase LCK OS=R... 289 4e-85
sp|P06240|LCK_MOUSE Proto-oncogene tyrosine-protein kinase LCK OS... 289 4e-85
sp|Q95M30|HCK_MACFA Tyrosine-protein kinase HCK OS=Macaca fascicu... 288 6e-85
sp|P00542|FES_FSVGA Tyrosine-protein kinase transforming protein ... 292 7e-85
sp|P29320|EPHA3_HUMAN Ephrin type-A receptor 3 OS=Homo sapiens OX... 300 9e-85
sp|P00544|FGR_FSVGR Tyrosine-protein kinase transforming protein ... 289 9e-85
sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens... 303 1e-84
sp|P00520|ABL1_MOUSE Tyrosine-protein kinase ABL1 OS=Mus musculus... 303 1e-84
sp|P06239|LCK_HUMAN Tyrosine-protein kinase Lck OS=Homo sapiens O... 288 1e-84
sp|Q5PXS1|LCK_AOTNA Tyrosine-protein kinase Lck OS=Aotus nancymaa... 288 1e-84
sp|P54756|EPHA5_HUMAN Ephrin type-A receptor 5 OS=Homo sapiens OX... 301 2e-84
sp|P08631|HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo sapiens O... 288 2e-84
sp|P54757|EPHA5_RAT Ephrin type-A receptor 5 OS=Rattus norvegicus... 299 5e-84
sp|P29321|EPHA8_RAT Ephrin type-A receptor 8 (Fragment) OS=Rattus... 281 6e-84
sp|P14238|FES_FELCA Tyrosine-protein kinase Fes/Fps OS=Felis catu... 295 7e-84
sp|Q03145|EPHA2_MOUSE Ephrin type-A receptor 2 OS=Mus musculus OX... 297 1e-83
sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens... 300 1e-83
sp|O08680|EPHA3_RAT Ephrin type-A receptor 3 OS=Rattus norvegicus... 297 1e-83
sp|P00522|ABL_DROME Tyrosine-protein kinase Abl OS=Drosophila mel... 303 2e-83
sp|P29318|EPHA3_CHICK Ephrin type-A receptor 3 OS=Gallus gallus O... 296 3e-83
sp|P16879|FES_MOUSE Tyrosine-protein kinase Fes/Fps OS=Mus muscul... 293 4e-83
sp|P00541|FPS_AVISP Tyrosine-protein kinase transforming protein ... 285 4e-83
sp|O13146|EPHA3_DANRE Ephrin type-A receptor 3 OS=Danio rerio OX=... 295 1e-82
sp|P29319|EPHA3_MOUSE Ephrin type-A receptor 3 OS=Mus musculus OX... 295 1e-82
sp|Q4JIM5|ABL2_MOUSE Tyrosine-protein kinase ABL2 OS=Mus musculus... 297 2e-82
sp|P08103|HCK_MOUSE Tyrosine-protein kinase HCK OS=Mus musculus O... 282 2e-82
sp|P16277|BLK_MOUSE Tyrosine-protein kinase Blk OS=Mus musculus O... 281 2e-82
sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens OX... 293 3e-82
sp|P42681|TXK_HUMAN Tyrosine-protein kinase TXK OS=Homo sapiens O... 282 3e-82
sp|P07332|FES_HUMAN Tyrosine-protein kinase Fes/Fps OS=Homo sapie... 290 4e-82
sp|P50545|HCK_RAT Tyrosine-protein kinase HCK OS=Rattus norvegicu... 281 4e-82
sp|P42682|TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus musculus O... 281 6e-82
sp|Q91736|EPB1B_XENLA Ephrin type-B receptor 1-B (Fragment) OS=Xe... 291 6e-82
sp|Q91694|EPA4B_XENLA Ephrin type-A receptor 4-B OS=Xenopus laevi... 292 9e-82
sp|Q91845|EPA4A_XENLA Ephrin type-A receptor 4-A OS=Xenopus laevi... 291 1e-81
sp|P54763|EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus musculus OX... 291 1e-81
sp|P21802|FGFR2_HUMAN Fibroblast growth factor receptor 2 OS=Homo... 288 1e-81
sp|Q1KL86|EPHA2_MACFA Ephrin type-A receptor 2 OS=Macaca fascicul... 291 1e-81
sp|P21804|FGFR1_CHICK Fibroblast growth factor receptor 1 OS=Gall... 288 1e-81
sp|P18461|FGFR2_CHICK Fibroblast growth factor receptor 2 OS=Gall... 288 2e-81
sp|Q61772|EPHA7_MOUSE Ephrin type-A receptor 7 OS=Mus musculus OX... 291 2e-81
sp|O42422|EPHA7_CHICK Ephrin type-A receptor 7 OS=Gallus gallus O... 291 3e-81
sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens OX... 291 3e-81
sp|P54759|EPHA7_RAT Ephrin type-A receptor 7 OS=Rattus norvegicus... 290 4e-81
sp|Q15375|EPHA7_HUMAN Ephrin type-A receptor 7 OS=Homo sapiens OX... 290 4e-81
sp|P28693|EPHB2_CHICK Ephrin type-B receptor 2 OS=Gallus gallus O... 290 4e-81
sp|P16092|FGFR1_MOUSE Fibroblast growth factor receptor 1 OS=Mus ... 287 4e-81
sp|Q03137|EPHA4_MOUSE Ephrin type-A receptor 4 OS=Mus musculus OX... 290 4e-81
sp|P54764|EPHA4_HUMAN Ephrin type-A receptor 4 OS=Homo sapiens OX... 290 4e-81
sp|Q07496|EPHA4_CHICK Ephrin type-A receptor 4 OS=Gallus gallus O... 290 4e-81
sp|P11362|FGFR1_HUMAN Fibroblast growth factor receptor 1 OS=Homo... 287 4e-81
sp|Q04589|FGFR1_RAT Fibroblast growth factor receptor 1 OS=Rattus... 286 5e-81
sp|P21803|FGFR2_MOUSE Fibroblast growth factor receptor 2 OS=Mus ... 286 6e-81
sp|P09759|EPHB1_RAT Ephrin type-B receptor 1 OS=Rattus norvegicus... 290 7e-81
sp|Q8CBF3|EPHB1_MOUSE Ephrin type-B receptor 1 OS=Mus musculus OX... 290 7e-81
sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo sapiens OX... 289 9e-81
sp|Q91287|FGFR3_PLEWA Fibroblast growth factor receptor 3 OS=Pleu... 285 1e-80
sp|P03949|ABL1_CAEEL Tyrosine-protein kinase abl-1 OS=Caenorhabdi... 292 1e-80
sp|Q91147|FGFR2_NOTVI Fibroblast growth factor receptor 2 OS=Noto... 283 1e-80
sp|Q91285|FGFR1_PLEWA Fibroblast growth factor receptor 1 OS=Pleu... 285 2e-80
sp|P18460|FGFR3_CHICK Fibroblast growth factor receptor 3 OS=Gall... 285 2e-80
sp|Q64434|PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus musculus OX... 274 2e-80
sp|Q13882|PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo sapiens OX... 274 3e-80
sp|Q91735|EPHB3_XENLA Ephrin type-B receptor 3 OS=Xenopus laevis ... 287 3e-80
sp|P22607|FGFR3_HUMAN Fibroblast growth factor receptor 3 OS=Homo... 284 3e-80
sp|Q8JH64|BTK_CHICK Tyrosine-protein kinase BTK OS=Gallus gallus ... 280 4e-80
sp|Q90344|EPHB2_COTJA Ephrin type-B receptor 2 OS=Coturnix japoni... 287 4e-80
sp|Q8JG38|FGFR2_DANRE Fibroblast growth factor receptor 2 OS=Dani... 284 4e-80
sp|O13147|EPHB3_DANRE Ephrin type-B receptor 3 (Fragment) OS=Dani... 275 4e-80
sp|Q0VBZ0|CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos taurus OX=... 273 5e-80
sp|P41240|CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo sapiens O... 273 6e-80
sp|P22182|FGFR1_XENLA Fibroblast growth factor receptor 1 OS=Xeno... 283 7e-80
sp|P32577|CSK_RAT Tyrosine-protein kinase CSK OS=Rattus norvegicu... 273 7e-80
sp|P41241|CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus musculus O... 272 1e-79
sp|Q498D6|FGFR4_RAT Fibroblast growth factor receptor 4 OS=Rattus... 282 1e-79
sp|P42680|TEC_HUMAN Tyrosine-protein kinase Tec OS=Homo sapiens O... 278 1e-79
sp|Q91288|FGFR4_PLEWA Fibroblast growth factor receptor 4 OS=Pleu... 282 2e-79
sp|Q61851|FGFR3_MOUSE Fibroblast growth factor receptor 3 OS=Mus ... 282 2e-79
sp|Q03364|FGFR2_XENLA Fibroblast growth factor receptor 2 OS=Xeno... 282 2e-79
sp|Q91286|FGFR2_PLEWA Fibroblast growth factor receptor 2 OS=Pleu... 281 3e-79
sp|Q07494|EPHB1_CHICK Ephrin type-B receptor 1 (Fragment) OS=Gall... 285 3e-79
sp|P51451|BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo sapiens O... 272 4e-79
sp|P24604|TEC_MOUSE Tyrosine-protein kinase Tec OS=Mus musculus O... 276 4e-79
sp|Q90Z00|FGR1A_DANRE Fibroblast growth factor receptor 1-A OS=Da... 281 4e-79
sp|P27450|CST_ARATH Probable serine/threonine-protein kinase CST ... 269 4e-79
sp|Q5XF79|PBL18_ARATH Probable serine/threonine-protein kinase PB... 268 5e-79
sp|P41239|CSK_CHICK Tyrosine-protein kinase CSK OS=Gallus gallus ... 270 5e-79
sp|Q07497|EPHB5_CHICK Ephrin type-B receptor 5 OS=Gallus gallus O... 284 5e-79
sp|Q6VNS1|NTRK3_MOUSE NT-3 growth factor receptor OS=Mus musculus... 281 6e-79
sp|Q91044|NTRK3_CHICK NT-3 growth factor receptor OS=Gallus gallu... 281 6e-79
sp|P29322|EPHA8_HUMAN Ephrin type-A receptor 8 OS=Homo sapiens OX... 284 7e-79
sp|Q91987|NTRK2_CHICK BDNF/NT-3 growth factors receptor OS=Gallus... 280 8e-79
sp|Q5IFJ9|NTRK3_MACFA NT-3 growth factor receptor OS=Macaca fasci... 280 9e-79
sp|Q5IS37|NTRK3_PANTR NT-3 growth factor receptor OS=Pan troglody... 280 9e-79
sp|Q54H45|DRKB_DICDI Probable serine/threonine-protein kinase drk... 277 1e-78
sp|P54754|EPHB3_MOUSE Ephrin type-B receptor 3 OS=Mus musculus OX... 283 1e-78
sp|Q86PM4|FGFR_HYDVU Fibroblast growth factor receptor OS=Hydra v... 280 1e-78
sp|Q3UFB7|NTRK1_MOUSE High affinity nerve growth factor receptor ... 278 2e-78
sp|Q90413|FGFR4_DANRE Fibroblast growth factor receptor 4 OS=Dani... 281 2e-78
sp|O42127|FGFR3_XENLA Fibroblast growth factor receptor 3 OS=Xeno... 278 2e-78
sp|P22455|FGFR4_HUMAN Fibroblast growth factor receptor 4 OS=Homo... 278 3e-78
sp|Q06187|BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo sapiens O... 275 3e-78
sp|P00530|FPS_FUJSV Tyrosine-protein kinase transforming protein ... 280 3e-78
sp|P24786|NTRK3_PIG NT-3 growth factor receptor OS=Sus scrofa OX=... 278 4e-78
sp|P35739|NTRK1_RAT High affinity nerve growth factor receptor OS... 278 4e-78
sp|O22558|STY8_ARATH Serine/threonine-protein kinase STY8 OS=Arab... 271 4e-78
sp|F4JTP5|STY46_ARATH Serine/threonine-protein kinase STY46 OS=Ar... 272 4e-78
sp|P35991|BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus musculus O... 274 6e-78
sp|O48814|BIK1_ARATH Serine/threonine-protein kinase BIK1 OS=Arab... 265 7e-78
sp|P54758|EPHA6_RAT Ephrin type-A receptor 6 OS=Rattus norvegicus... 281 7e-78
sp|Q9LTC0|PBL19_ARATH Probable serine/threonine-protein kinase PB... 265 1e-77
sp|Q07407|FGFR1_DROME Fibroblast growth factor receptor homolog 1... 275 1e-77
sp|Q5IS82|NTRK3_SAIBB NT-3 growth factor receptor OS=Saimiri boli... 276 2e-77
sp|Q2MHE4|HT1_ARATH Serine/threonine/tyrosine-protein kinase HT1 ... 264 2e-77
sp|Q90330|FGFR4_COTCO Fibroblast growth factor receptor 4 OS=Cotu... 273 3e-77
sp|Q91571|EPB1A_XENLA Ephrin type-B receptor 1-A OS=Xenopus laevi... 279 4e-77
sp|P53356|HTK16_HYDVU Tyrosine-protein kinase HTK16 OS=Hydra vulg... 274 4e-77
sp|Q9I8X3|FGFR3_DANRE Fibroblast growth factor receptor 3 OS=Dani... 275 4e-77
sp|Q08881|ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=Homo sapie... 270 5e-77
sp|Q8GXZ3|PBL8_ARATH Probable serine/threonine-protein kinase PBL... 263 6e-77
sp|Q5PP29|PBL4_ARATH Probable serine/threonine-protein kinase PBL... 263 6e-77
sp|Q9LFP7|PBL34_ARATH Serine/threonine-protein kinase PBL34 OS=Ar... 266 8e-77
sp|P41242|MATK_MOUSE Megakaryocyte-associated tyrosine-protein ki... 266 8e-77
sp|O73878|EPB4B_DANRE Ephrin type-B receptor 4b OS=Danio rerio OX... 277 9e-77
sp|P54761|EPHB4_MOUSE Ephrin type-B receptor 4 OS=Mus musculus OX... 278 9e-77
sp|Q63604|NTRK2_RAT BDNF/NT-3 growth factors receptor OS=Rattus n... 274 9e-77
sp|P54753|EPHB3_HUMAN Ephrin type-B receptor 3 OS=Homo sapiens OX... 278 9e-77
sp|P00529|ROS_AVISU Tyrosine-protein kinase transforming protein ... 262 1e-76
sp|Q65XV8|RK176_ORYSJ Receptor-like cytoplasmic kinase 176 OS=Ory... 261 1e-76
sp|P08630|BTKL_DROME Tyrosine-protein kinase Btk OS=Drosophila me... 273 1e-76
sp|P15209|NTRK2_MOUSE BDNF/NT-3 growth factors receptor OS=Mus mu... 274 1e-76
sp|Q16620|NTRK2_HUMAN BDNF/NT-3 growth factors receptor OS=Homo s... 274 1e-76
sp|Q54H46|DRKA_DICDI Probable serine/threonine-protein kinase drk... 269 2e-76
sp|P43293|PBL11_ARATH Probable serine/threonine-protein kinase PB... 261 2e-76
sp|O09127|EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus musculus OX... 276 2e-76
sp|P41243|MATK_RAT Megakaryocyte-associated tyrosine-protein kina... 263 2e-76
sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens OX... 276 3e-76
sp|Q07498|EPHB3_CHICK Ephrin type-B receptor 3 (Fragment) OS=Gall... 276 3e-76
sp|Q55GU0|Y9955_DICDI Probable serine/threonine-protein kinase DD... 275 4e-76
sp|G5ECJ6|CSK1_CAEEL Tyrosine-protein kinase csk-1 OS=Caenorhabdi... 265 4e-76
sp|Q9SFT7|PBL26_ARATH Probable serine/threonine-protein kinase PB... 261 4e-76
sp|Q8RWL6|STY17_ARATH Serine/threonine-protein kinase STY17 OS=Ar... 266 5e-76
sp|Q9SRH7|PBL35_ARATH Serine/threonine-protein kinase PBL35 OS=Ar... 263 5e-76
sp|Q62413|EPHA6_MOUSE Ephrin type-A receptor 6 OS=Mus musculus OX... 276 5e-76
sp|Q03142|FGFR4_MOUSE Fibroblast growth factor receptor 4 OS=Mus ... 271 9e-76
sp|Q62270|SRMS_MOUSE Tyrosine-protein kinase Srms OS=Mus musculus... 263 1e-75
sp|Q9UF33|EPHA6_HUMAN Ephrin type-A receptor 6 OS=Homo sapiens OX... 275 1e-75
sp|Q91743|FGFR4_XENLA Fibroblast growth factor receptor 4 OS=Xeno... 271 1e-75
sp|Q8H186|PBL1_ARATH Probable serine/threonine-protein kinase PBL... 259 1e-75
sp|O73875|EPB4A_DANRE Ephrin type-B receptor 4a OS=Danio rerio OX... 274 1e-75
sp|P43404|ZAP70_MOUSE Tyrosine-protein kinase ZAP-70 OS=Mus muscu... 266 1e-75
sp|P46573|PBL10_ARATH Probable serine/threonine-protein kinase PB... 259 1e-75
sp|Q03526|ITK_MOUSE Tyrosine-protein kinase ITK/TSK OS=Mus muscul... 266 1e-75
sp|Q9SII6|PIX13_ARATH Probable serine/threonine-protein kinase PI... 259 2e-75
sp|Q16288|NTRK3_HUMAN NT-3 growth factor receptor OS=Homo sapiens... 271 2e-75
sp|Q9C9U5|SIS8_ARATH Probable serine/threonine-protein kinase SIS... 274 2e-75
sp|Q24488|ROR1_DROME Tyrosine-protein kinase transmembrane recept... 267 2e-75
sp|Q9FE20|PBS1_ARATH Serine/threonine-protein kinase PBS1 OS=Arab... 260 3e-75
sp|Q06548|PBL9_ARATH Probable serine/threonine-protein kinase PBL... 258 3e-75
sp|Q84M95|PBL28_ARATH Probable serine/threonine-protein kinase PB... 257 4e-75
sp|P43403|ZAP70_HUMAN Tyrosine-protein kinase ZAP-70 OS=Homo sapi... 265 4e-75
sp|P33497|RYK_AVIR3 Tyrosine-protein kinase transforming protein ... 259 4e-75
sp|Q54TM7|DRKD_DICDI Probable serine/threonine-protein kinase drk... 275 6e-75
sp|Q9H3Y6|SRMS_HUMAN Tyrosine-protein kinase Srms OS=Homo sapiens... 260 7e-75
sp|Q9LDZ5|PBL21_ARATH Probable serine/threonine-protein kinase PB... 256 7e-75
sp|P04629|NTRK1_HUMAN High affinity nerve growth factor receptor ... 268 8e-75
sp|P42679|MATK_HUMAN Megakaryocyte-associated tyrosine-protein ki... 260 1e-74
sp|P07949|RET_HUMAN Proto-oncogene tyrosine-protein kinase recept... 273 1e-74
sp|Q91009|NTRK1_CHICK High affinity nerve growth factor receptor ... 267 1e-74
sp|Q06807|TIE2_BOVIN Angiopoietin-1 receptor OS=Bos taurus OX=991... 273 1e-74
sp|Q4H3K6|FGFR_CIOIN Fibroblast growth factor receptor OS=Ciona i... 266 1e-74
sp|G3V9H8|RET_RAT Proto-oncogene tyrosine-protein kinase receptor... 273 1e-74
sp|Q02763|TIE2_HUMAN Angiopoietin-1 receptor OS=Homo sapiens OX=9... 273 1e-74
sp|Q02858|TIE2_MOUSE Angiopoietin-1 receptor OS=Mus musculus OX=1... 273 2e-74
sp|Q8VYG0|LRL13_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 264 2e-74
sp|Q0WRY5|PBL7_ARATH Probable serine/threonine-protein kinase PBL... 254 2e-74
sp|Q95YM9|FGFR_HALRO Fibroblast growth factor receptor OS=Halocyn... 266 2e-74
sp|P16056|MET_MOUSE Hepatocyte growth factor receptor OS=Mus musc... 274 3e-74
sp|F4J0D2|PBL36_ARATH Serine/threonine-protein kinase PBL36 OS=Ar... 258 3e-74
sp|O15146|MUSK_HUMAN Muscle, skeletal receptor tyrosine-protein k... 268 3e-74
sp|Q7TPS0|KS6A6_MOUSE Ribosomal protein S6 kinase alpha-6 OS=Mus ... 266 3e-74
sp|Q9LRY1|PBL25_ARATH Probable serine/threonine-protein kinase PB... 254 3e-74
sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens OX=9... 271 3e-74
sp|P21709|EPHA1_HUMAN Ephrin type-A receptor 1 OS=Homo sapiens OX... 270 3e-74
sp|Q09YN5|MET_RABIT Hepatocyte growth factor receptor OS=Oryctola... 273 4e-74
sp|P70600|FAK2_RAT Protein-tyrosine kinase 2-beta OS=Rattus norve... 270 4e-74
sp|Q5UQG7|YR818_MIMIV Putative serine/threonine-protein kinase/re... 274 4e-74
sp|P35546|RET_MOUSE Proto-oncogene tyrosine-protein kinase recept... 271 4e-74
sp|Q9SY91|PBL15_ARATH Probable serine/threonine-protein kinase PB... 255 5e-74
sp|Q7T6Y2|YR831_MIMIV Putative serine/threonine-protein kinase/re... 274 5e-74
sp|Q2QLH6|MET_OTOGA Hepatocyte growth factor receptor OS=Otolemur... 273 5e-74
sp|P18106|FER_DROME Tyrosine-protein kinase Fer OS=Drosophila mel... 273 6e-74
sp|Q9SFX0|PBL22_ARATH Probable serine/threonine-protein kinase PB... 253 7e-74
sp|Q2IBC0|MET_RHIFE Hepatocyte growth factor receptor OS=Rhinolop... 273 7e-74
sp|Q9QVP9|FAK2_MOUSE Protein-tyrosine kinase 2-beta OS=Mus muscul... 270 7e-74
sp|Q9VBW3|CAD96_DROME Tyrosine kinase receptor Cad96Ca OS=Drosoph... 265 7e-74
sp|Q2QLG5|MET_CALJA Hepatocyte growth factor receptor OS=Callithr... 273 8e-74
sp|Q1PDV6|PBL27_ARATH Serine/threonine-protein kinase PBL27 OS=Ar... 258 8e-74
sp|Q8AXY6|MUSK_CHICK Muscle, skeletal receptor tyrosine protein k... 268 9e-74
sp|Q2QL89|MET_MICMU Hepatocyte growth factor receptor OS=Microceb... 272 1e-73
sp|Q2QLC0|MET_PLEMO Hepatocyte growth factor receptor OS=Plecturo... 272 1e-73
sp|Q07DY1|MET_NOMLE Hepatocyte growth factor receptor OS=Nomascus... 272 1e-73
sp|P08581|MET_HUMAN Hepatocyte growth factor receptor OS=Homo sap... 272 1e-73
sp|Q2IBF2|MET_GORGO Hepatocyte growth factor receptor OS=Gorilla ... 272 1e-73
sp|Q2QLF1|MET_PANTR Hepatocyte growth factor receptor OS=Pan trog... 272 1e-73
sp|Q2IBD8|MET_PONAB Hepatocyte growth factor receptor OS=Pongo ab... 272 1e-73
sp|Q07DZ1|MET_COLGU Hepatocyte growth factor receptor OS=Colobus ... 272 1e-73
sp|P51813|BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX OS=Ho... 262 1e-73
sp|Q09YL1|MET_ATEGE Hepatocyte growth factor receptor OS=Ateles g... 272 1e-73
sp|Q09YH7|MET_SAIBB Hepatocyte growth factor receptor OS=Saimiri ... 272 1e-73
sp|F4JZW1|PBL13_ARATH Serine/threonine-protein kinase PBL13 OS=Ar... 257 1e-73
sp|P34152|FAK1_MOUSE Focal adhesion kinase 1 OS=Mus musculus OX=1... 269 1e-73
sp|Q07DV8|MET_AOTNA Hepatocyte growth factor receptor OS=Aotus na... 272 1e-73
sp|Q2IBG7|MET_EULMM Hepatocyte growth factor receptor OS=Eulemur ... 272 1e-73
sp|Q54TA1|DRKC_DICDI Probable serine/threonine-protein kinase drk... 264 1e-73
sp|A0M8R7|MET_PAPAN Hepatocyte growth factor receptor OS=Papio an... 272 1e-73
sp|Q1PE89|PBL24_ARATH Probable serine/threonine-protein kinase PB... 253 1e-73
sp|Q07E48|MET_DASNO Hepatocyte growth factor receptor OS=Dasypus ... 272 1e-73
sp|O35346|FAK1_RAT Focal adhesion kinase 1 OS=Rattus norvegicus O... 269 1e-73
sp|Q2IBA6|MET_CHLAE Hepatocyte growth factor receptor OS=Chloroce... 272 1e-73
sp|O49840|PBL3_ARATH Probable serine/threonine-protein kinase PBL... 254 1e-73
sp|Q09YK0|MET_MUNMU Hepatocyte growth factor receptor OS=Muntiacu... 272 2e-73
sp|Q60750|EPHA1_MOUSE Ephrin type-A receptor 1 OS=Mus musculus OX... 268 2e-73
sp|Q00PJ8|MET_ATEAB Hepatocyte growth factor receptor OS=Atelerix... 271 2e-73
sp|Q09147|FGFR2_DROME Fibroblast growth factor receptor homolog 2... 269 2e-73
sp|Q62838|MUSK_RAT Muscle, skeletal receptor tyrosine protein kin... 265 2e-73
sp|Q8GYA4|CRK10_ARATH Cysteine-rich receptor-like protein kinase ... 261 2e-73
sp|Q9M0X5|CRK25_ARATH Cysteine-rich receptor-like protein kinase ... 261 3e-73
sp|Q07E24|MET_MUSPF Hepatocyte growth factor receptor OS=Mustela ... 271 3e-73
sp|Q9ZQ31|STY13_ARATH Serine/threonine-protein kinase STY13 OS=Ar... 253 3e-73
sp|Q75ZY9|MET_CANLF Hepatocyte growth factor receptor OS=Canis lu... 271 3e-73
sp|O49564|CRK27_ARATH Cysteine-rich receptor-like protein kinase ... 260 3e-73
sp|Q2QLA9|MET_HORSE Hepatocyte growth factor receptor OS=Equus ca... 271 3e-73
sp|Q54RB7|SHKA_DICDI Dual specificity protein kinase shkA OS=Dict... 256 4e-73
sp|F4JEQ2|PBL23_ARATH Probable serine/threonine-protein kinase PB... 251 4e-73
sp|Q769I5|MET_BOVIN Hepatocyte growth factor receptor OS=Bos taur... 271 4e-73
sp|Q2QLE0|MET_PIG Hepatocyte growth factor receptor OS=Sus scrofa... 270 4e-73
sp|Q09YI9|MET_SHEEP Hepatocyte growth factor receptor OS=Ovis ari... 270 5e-73
sp|O49839|PBL2_ARATH Probable serine/threonine-protein kinase PBL... 253 5e-73
sp|Q07E37|MET_NEONE Hepatocyte growth factor receptor OS=Neofelis... 270 5e-73
sp|A0M8S8|MET_FELCA Hepatocyte growth factor receptor OS=Felis ca... 270 5e-73
sp|A1X150|MET_ECHTE Hepatocyte growth factor receptor OS=Echinops... 270 5e-73
sp|Q61006|MUSK_MOUSE Muscle, skeletal receptor tyrosine-protein k... 264 6e-73
sp|Q05688|IGF1R_BOVIN Insulin-like growth factor 1 receptor (Frag... 259 6e-73
sp|Q9FGB1|CBC2_ARATH Serine/threonine-protein kinase 52 OS=Arabid... 251 6e-73
sp|Q14289|FAK2_HUMAN Protein-tyrosine kinase 2-beta OS=Homo sapie... 266 6e-73
sp|Q108U6|MET_LOXAF Hepatocyte growth factor receptor OS=Loxodont... 270 7e-73
sp|Q8GWJ7|CRK19_ARATH Cysteine-rich receptor-like protein kinase ... 259 7e-73
sp|Q9SSA4|CBC1_ARATH Serine/threonine-protein kinase 54 OS=Arabid... 251 8e-73
sp|Q62371|DDR2_MOUSE Discoidin domain-containing receptor 2 OS=Mu... 263 8e-73
sp|Q9SYM9|Y1853_ARATH Receptor-like serine/threonine-protein kina... 249 8e-73
sp|Q9CAH1|Y1725_ARATH Putative receptor-like protein kinase At1g7... 253 9e-73
sp|P97504|BMX_MOUSE Cytoplasmic tyrosine-protein kinase BMX OS=Mu... 258 1e-72
sp|Q07E01|MET_ORNAN Hepatocyte growth factor receptor OS=Ornithor... 269 1e-72
sp|Q06806|TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mu... 267 1e-72
sp|Q9XI87|VIK_ARATH Serine/threonine-protein kinase VIK OS=Arabid... 252 1e-72
sp|Q9LQQ8|PBL5_ARATH Probable serine/threonine-protein kinase PBL... 251 2e-72
sp|F4HQ17|LRL14_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 258 2e-72
sp|Q86AT8|SPKA_DICDI Stress-activated protein kinase alpha OS=Dic... 257 2e-72
sp|Q9ZUF4|RIPK_ARATH Serine/threonine-protein kinase RIPK OS=Arab... 252 2e-72
sp|Q03351|NTRK3_RAT NT-3 growth factor receptor OS=Rattus norvegi... 262 3e-72
sp|P23049|SEA_AVIET Tyrosine-protein kinase transforming protein ... 248 3e-72
sp|Q16832|DDR2_HUMAN Discoidin domain-containing receptor 2 OS=Ho... 262 3e-72
sp|Q26614|FGFR_STRPU Fibroblast growth factor receptor OS=Strongy... 264 4e-72
sp|Q00944|FAK1_CHICK Focal adhesion kinase 1 OS=Gallus gallus OX=... 265 4e-72
sp|O81906|B120_ARATH G-type lectin S-receptor-like serine/threoni... 261 4e-72
sp|Q8H1E3|PBL17_ARATH Probable serine/threonine-protein kinase PB... 250 5e-72
sp|P35590|TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 OS=Ho... 265 5e-72
sp|Q95YD4|KIN32_CAEEL Inactive tyrosine-protein kinase kin-32 OS=... 261 5e-72
sp|O65479|CRK20_ARATH Putative cysteine-rich receptor-like protei... 257 7e-72
sp|Q06805|TIE1_BOVIN Tyrosine-protein kinase receptor Tie-1 OS=Bo... 265 7e-72
sp|Q9SYA0|Y1150_ARATH G-type lectin S-receptor-like serine/threon... 260 7e-72
sp|P42687|SPK1_GIRTI Tyrosine-protein kinase SPK-1 OS=Girardia ti... 252 7e-72
sp|P97523|MET_RAT Hepatocyte growth factor receptor OS=Rattus nor... 266 8e-72
sp|Q91738|FAK1_XENLA Focal adhesion kinase 1 OS=Xenopus laevis OX... 264 8e-72
sp|F1N9Y5|KSYK_CHICK Tyrosine-protein kinase SYK OS=Gallus gallus... 255 8e-72
sp|Q3U1V8|M3K9_MOUSE Mitogen-activated protein kinase kinase kina... 264 9e-72
sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kin... 260 9e-72
sp|Q8MY86|FGFR1_DUGJA Fibroblast growth factor receptor 1 OS=Duge... 260 9e-72
sp|Q61527|ERBB4_MOUSE Receptor tyrosine-protein kinase erbB-4 OS=... 266 9e-72
sp|Q05609|CTR1_ARATH Serine/threonine-protein kinase CTR1 OS=Arab... 260 1e-71
sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kinas... 260 1e-71
sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase kin... 260 1e-71
sp|Q9SIB6|PBL6_ARATH Probable serine/threonine-protein kinase PBL... 249 1e-71
sp|Q7T6X2|YR826_MIMIV Putative serine/threonine-protein kinase/re... 266 1e-71
sp|Q78DX7|ROS1_MOUSE Proto-oncogene tyrosine-protein kinase ROS O... 267 1e-71
sp|F4JPX3|PBL20_ARATH Probable serine/threonine-protein kinase PB... 247 2e-71
sp|Q3EDL4|Y1154_ARATH Probable serine/threonine-protein kinase At... 250 2e-71
sp|Q93YN1|CRPK1_ARATH Cold-responsive protein kinase 1 OS=Arabido... 247 2e-71
sp|Q9LZU4|CRK4_ARATH Cysteine-rich receptor-like protein kinase 4... 256 2e-71
sp|P80192|M3K9_HUMAN Mitogen-activated protein kinase kinase kina... 263 2e-71
sp|Q63132|ROS1_RAT Proto-oncogene tyrosine-protein kinase ROS OS=... 266 2e-71
sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens OX=... 262 2e-71
sp|Q1RMT8|IRAK4_BOVIN Interleukin-1 receptor-associated kinase 4 ... 249 2e-71
sp|Q15303|ERBB4_HUMAN Receptor tyrosine-protein kinase erbB-4 OS=... 265 3e-71
sp|Q9YI66|TYRO3_DANRE Tyrosine-protein kinase receptor TYRO3 OS=D... 259 3e-71
sp|P57097|MERTK_RAT Tyrosine-protein kinase Mer OS=Rattus norvegi... 261 3e-71
sp|O54967|ACK1_MOUSE Activated CDC42 kinase 1 OS=Mus musculus OX=... 261 5e-71
sp|P11273|ERBB_AVIEU Tyrosine-protein kinase transforming protein... 251 5e-71
sp|Q9SYS7|CRK39_ARATH Putative cysteine-rich receptor-like protei... 254 6e-71
sp|Q93105|INSR_AEDAE Insulin-like receptor OS=Aedes aegypti OX=71... 264 7e-71
sp|O64771|Y1148_ARATH G-type lectin S-receptor-like serine/threon... 257 7e-71
sp|Q04912|RON_HUMAN Macrophage-stimulating protein receptor OS=Ho... 263 9e-71
sp|Q9FG33|LRKS5_ARATH Probable L-type lectin-domain containing re... 253 9e-71
sp|Q5U2X5|ACK1_RAT Activated CDC42 kinase 1 OS=Rattus norvegicus ... 260 9e-71
sp|Q8RWW0|ALE2_ARATH Receptor-like serine/threonine-protein kinas... 255 1e-70
sp|P08922|ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS O... 264 1e-70
sp|Q9FM85|PBL16_ARATH Probable serine/threonine-protein kinase PB... 245 1e-70
sp|Q75JK0|ZAK1_DICDI Dual specificity protein kinase zakA OS=Dict... 256 1e-70
sp|Q12866|MERTK_HUMAN Tyrosine-protein kinase Mer OS=Homo sapiens... 260 1e-70
sp|Q54Y55|SHKC_DICDI Dual specificity protein kinase shkC OS=Dict... 249 1e-70
sp|Q9SJG2|Y2296_ARATH Probable receptor-like protein kinase At2g4... 248 1e-70
sp|Q60805|MERTK_MOUSE Tyrosine-protein kinase Mer OS=Mus musculus... 259 1e-70
sp|Q62190|RON_MOUSE Macrophage-stimulating protein receptor OS=Mu... 263 1e-70
sp|D3ZG83|M3K10_RAT Mitogen-activated protein kinase kinase kinas... 259 1e-70
sp|Q17R13|ACK1_BOVIN Activated CDC42 kinase 1 OS=Bos taurus OX=99... 260 1e-70
sp|Q24145|SHARK_DROME Tyrosine-protein kinase Shark OS=Drosophila... 258 1e-70
sp|O73798|IGF1R_XENLA Insulin-like growth factor 1 receptor OS=Xe... 263 1e-70
sp|Q9M8S2|LIPG2_ARATH Receptor-like kinase LIP2 OS=Arabidopsis th... 250 2e-70
sp|Q8MY85|FGFR2_DUGJA Fibroblast growth factor receptor 2 OS=Duge... 258 2e-70
sp|Q66L42|M3K10_MOUSE Mitogen-activated protein kinase kinase kin... 258 2e-70
sp|Q6NKZ9|Y4345_ARATH Probable receptor-like serine/threonine-pro... 246 2e-70
sp|Q9SY89|Y1661_ARATH Putative G-type lectin S-receptor-like seri... 257 2e-70
sp|C0LGD7|Y1684_ARATH Probable LRR receptor-like serine/threonine... 259 2e-70
sp|Q9NWZ3|IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 ... 246 2e-70
sp|Q62956|ERBB4_RAT Receptor tyrosine-protein kinase erbB-4 OS=Ra... 262 2e-70
sp|P13388|XMRK_XIPMA Melanoma receptor tyrosine-protein kinase OS... 261 2e-70
sp|D2IYS2|TORSO_BOMMO Tyrosine-protein kinase receptor torso OS=B... 256 2e-70
sp|Q25410|MIPR_LYMST Putative molluscan insulin-related peptide(s... 263 2e-70
sp|Q9C5S8|CRK5_ARATH Cysteine-rich receptor-like protein kinase 5... 252 3e-70
sp|Q03146|DDR1_MOUSE Epithelial discoidin domain-containing recep... 257 3e-70
sp|Q9SYS3|CRK40_ARATH Cysteine-rich receptor-like protein kinase ... 252 3e-70
sp|P0C5E2|LRL12_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 251 3e-70
sp|Q9FID9|Y5389_ARATH Probable receptor-like protein kinase At5g3... 256 3e-70
sp|H2KZU7|SVH2_CAEEL Tyrosine-protein kinase receptor svh-2 OS=Ca... 259 3e-70
sp|D7UPN3|RLK10_ORYSJ LysM domain receptor-like kinase 10 OS=Oryz... 250 3e-70
sp|Q9Z139|ROR1_MOUSE Inactive tyrosine-protein kinase transmembra... 257 3e-70
sp|P00534|ERBB_ALV Tyrosine-protein kinase transforming protein e... 251 4e-70
sp|O64778|Y1142_ARATH G-type lectin S-receptor-like serine/threon... 255 4e-70
sp|O22040|ANP1_ARATH Mitogen-activated protein kinase kinase kina... 251 4e-70
sp|P06213|INSR_HUMAN Insulin receptor OS=Homo sapiens OX=9606 GN=... 261 4e-70
sp|Q55A09|Y9963_DICDI Probable serine/threonine-protein kinase DD... 261 4e-70
sp|Q02779|M3K10_HUMAN Mitogen-activated protein kinase kinase kin... 257 5e-70
sp|Q7T2V3|M3K10_XENLA Mitogen-activated protein kinase kinase kin... 258 5e-70
sp|Q9SF86|PCRK1_ARATH Serine/threonine-protein kinase PCRK1 OS=Ar... 244 6e-70
sp|O64780|Y1614_ARATH G-type lectin S-receptor-like serine/threon... 254 6e-70
sp|Q22146|FRK1_CAEEL Fer-related kinase 1 OS=Caenorhabditis elega... 243 6e-70
sp|Q9FZ36|M3K2_ARATH Mitogen-activated protein kinase kinase kina... 251 6e-70
sp|A2VDU3|M3K7_BOVIN Mitogen-activated protein kinase kinase kina... 249 6e-70
sp|Q62073|M3K7_MOUSE Mitogen-activated protein kinase kinase kina... 248 7e-70
sp|Q7YR43|DDR1_PANTR Epithelial discoidin domain-containing recep... 256 8e-70
sp|Q08345|DDR1_HUMAN Epithelial discoidin domain-containing recep... 256 8e-70
sp|Q0D5R3|CRK6_ORYSJ Cysteine-rich receptor-like protein kinase 6... 251 8e-70
sp|Q9FFW5|PERK8_ARATH Proline-rich receptor-like protein kinase P... 251 9e-70
sp|Q9XEC6|CRK36_ARATH Cysteine-rich receptor-like protein kinase ... 250 1e-69
sp|O73791|TIE2_DANRE Angiopoietin-1 receptor OS=Danio rerio OX=79... 258 1e-69
sp|P0C8E4|M3K7_RAT Mitogen-activated protein kinase kinase kinase... 249 1e-69
sp|Q5RFL3|M3K7_PONAB Mitogen-activated protein kinase kinase kina... 249 1e-69
sp|O43318|M3K7_HUMAN Mitogen-activated protein kinase kinase kina... 249 1e-69
sp|C0LGE0|Y1765_ARATH Probable LRR receptor-like serine/threonine... 257 1e-69
sp|Q9SR05|ANX1_ARATH Receptor-like protein kinase ANXUR1 OS=Arabi... 254 1e-69
sp|Q98949|TYRO3_CHICK Tyrosine-protein kinase receptor TYRO3 OS=G... 254 1e-69
sp|P08941|ROS1_CHICK Proto-oncogene tyrosine-protein kinase ROS O... 260 2e-69
sp|Q9LRP3|Y3174_ARATH Probable receptor-like protein kinase At3g1... 244 2e-69
sp|Q9ASQ5|CRCK3_ARATH Calmodulin-binding receptor-like cytoplasmi... 245 2e-69
sp|O22042|M3K3_ARATH Mitogen-activated protein kinase kinase kina... 249 2e-69
sp|Q9C6K9|LRL11_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 249 2e-69
sp|O76997|TRK1_LYMST Putative neurotrophin receptor LTRK 1 OS=Lym... 253 2e-69
sp|O64781|Y1639_ARATH G-type lectin S-receptor-like serine/threon... 253 2e-69
sp|O65472|CRK12_ARATH Putative cysteine-rich receptor-like protei... 249 2e-69
sp|Q9LSE1|CDG1_ARATH Serine/threonine-protein kinase CDG1 OS=Arab... 243 2e-69
sp|P08069|IGF1R_HUMAN Insulin-like growth factor 1 receptor OS=Ho... 259 2e-69
sp|Q54VC0|Y9865_DICDI Probable serine/threonine-protein kinase DD... 242 2e-69
sp|P00535|ERBB_AVIER Tyrosine-protein kinase transforming protein... 248 2e-69
sp|Q8LEB6|Y5185_ARATH Probable receptor-like protein kinase At5g1... 244 3e-69
sp|O64784|Y1136_ARATH G-type lectin S-receptor-like serine/threon... 253 3e-69
sp|O81832|Y4729_ARATH G-type lectin S-receptor-like serine/threon... 252 3e-69
sp|Q3E8W4|ANX2_ARATH Receptor-like protein kinase ANXUR2 OS=Arabi... 253 3e-69
sp|Q9FIU5|CRLK1_ARATH Calcium/calmodulin-regulated receptor-like ... 243 3e-69
sp|P24062|IGF1R_RAT Insulin-like growth factor 1 receptor OS=Ratt... 258 3e-69
sp|Q9UM73|ALK_HUMAN ALK tyrosine kinase receptor OS=Homo sapiens ... 259 3e-69
sp|Q6I5Q6|RK185_ORYSJ Receptor-like cytoplasmic kinase 185 OS=Ory... 244 3e-69
sp|Q1PDW3|LIPG1_ARATH Receptor-like kinase LIP1 OS=Arabidopsis th... 248 3e-69
sp|Q9ZR08|Y4230_ARATH G-type lectin S-receptor-like serine/threon... 253 4e-69
sp|Q60751|IGF1R_MOUSE Insulin-like growth factor 1 receptor OS=Mu... 258 4e-69
sp|Q01973|ROR1_HUMAN Inactive tyrosine-protein kinase transmembra... 254 5e-69
sp|O65476|CRK16_ARATH Putative cysteine-rich receptor-like protei... 248 5e-69
sp|Q63474|DDR1_RAT Epithelial discoidin domain-containing recepto... 253 5e-69
sp|Q9NYL2|M3K20_HUMAN Mitogen-activated protein kinase kinase kin... 251 6e-69
sp|Q9LYN8|EMS1_ARATH Leucine-rich repeat receptor protein kinase ... 256 6e-69
sp|Q9ESL4|M3K20_MOUSE Mitogen-activated protein kinase kinase kin... 251 6e-69
sp|Q9FID8|Y5900_ARATH Putative receptor-like protein kinase At5g3... 253 7e-69
sp|C0LGU1|Y5374_ARATH Probable LRR receptor-like serine/threonine... 254 7e-69
sp|O65483|CRK24_ARATH Cysteine-rich receptor-like protein kinase ... 247 8e-69
sp|Q9XEC7|CRK37_ARATH Cysteine-rich receptor-like protein kinase ... 247 8e-69
sp|P97793|ALK_MOUSE ALK tyrosine kinase receptor OS=Mus musculus ... 258 8e-69
sp|C0LGU5|Y5457_ARATH Probable LRR receptor-like serine/threonine... 246 8e-69
sp|Q9CAC3|CRK43_ARATH Cysteine-rich receptor-like protein kinase ... 240 9e-69
sp|P0CY46|EGFR_APIME Epidermal growth factor receptor OS=Apis mel... 256 1e-68
sp|Q54L00|LIMKA_DICDI Probable LIM domain-containing serine/threo... 247 1e-68
sp|Q9ZT07|RKS1_ARATH G-type lectin S-receptor-like serine/threoni... 251 1e-68
sp|P15208|INSR_MOUSE Insulin receptor OS=Mus musculus OX=10090 GN... 256 1e-68
sp|Q9XEC8|CRK38_ARATH Cysteine-rich receptor-like protein kinase ... 247 1e-68
sp|Q9SXB8|Y1133_ARATH G-type lectin S-receptor-like serine/threon... 251 1e-68
sp|Q9M9E0|LRKS1_ARATH L-type lectin-domain containing receptor ki... 247 1e-68
sp|Q9PVZ4|INSR_XENLA Insulin receptor OS=Xenopus laevis OX=8355 G... 256 1e-68
sp|Q9FPR3|EDR1_ARATH Serine/threonine-protein kinase EDR1 OS=Arab... 253 1e-68
sp|Q25197|HTK7_HYDVU Putative insulin-like peptide receptor OS=Hy... 257 1e-68
sp|P0DV84|ALK_CANLF ALK tyrosine kinase receptor OS=Canis lupus f... 257 1e-68
sp|O64776|Y1144_ARATH G-type lectin S-receptor-like serine/threon... 250 2e-68
sp|A0JM20|TYRO3_XENTR Tyrosine-protein kinase receptor TYRO3 OS=X... 251 2e-68
sp|Q10656|EGL15_CAEEL Myoblast growth factor receptor egl-15 OS=C... 254 2e-68
sp|Q0D5R2|CRK10_ORYSJ Cysteine-rich receptor-like protein kinase ... 246 2e-68
sp|P15127|INSR_RAT Insulin receptor OS=Rattus norvegicus OX=10116... 256 2e-68
sp|Q95ZV7|DDRB_CAEEL Discoidin domain-containing receptor tyrosin... 249 2e-68
sp|O65482|CRK23_ARATH Putative cysteine-rich receptor-like protei... 250 2e-68
sp|Q8W4G6|CRK15_ARATH Cysteine-rich receptor-like protein kinase ... 246 2e-68
sp|Q41328|PTI1_SOLLC Pto-interacting protein 1 OS=Solanum lycoper... 237 2e-68
sp|O65468|CRK8_ARATH Cysteine-rich receptor-like protein kinase 8... 246 3e-68
sp|Q9SA25|WAKLG_ARATH Wall-associated receptor kinase-like 8 OS=A... 247 3e-68
sp|P13368|7LESS_DROME Protein sevenless OS=Drosophila melanogaste... 256 4e-68
sp|C0LGG8|Y5343_ARATH Probable LRR receptor-like serine/threonine... 253 4e-68
sp|P30530|UFO_HUMAN Tyrosine-protein kinase receptor UFO OS=Homo ... 250 5e-68
sp|P08923|LTK_MOUSE Leukocyte tyrosine kinase receptor OS=Mus mus... 250 5e-68
sp|O64842|PBL12_ARATH Probable serine/threonine-protein kinase PB... 238 6e-68
sp|A0A0P0XII1|CERK1_ORYSJ Chitin elicitor receptor kinase 1 OS=Or... 244 7e-68
sp|Q54XQ2|RCKA_DICDI RGS domain-containing serine/threonine-prote... 253 7e-68
sp|O64783|Y1137_ARATH G-type lectin S-receptor-like serine/threon... 248 8e-68
sp|Q9LDQ3|CRK34_ARATH Cysteine-rich receptor-like protein kinase ... 244 1e-67
sp|Q9ASQ6|Y1972_ARATH Probable LRR receptor-like serine/threonine... 251 1e-67
sp|O61460|VAB1_CAEEL Ephrin receptor 1 OS=Caenorhabditis elegans ... 252 1e-67
sp|Q8QFP9|TYRO3_XENLA Tyrosine-protein kinase receptor TYRO3 OS=X... 249 1e-67
sp|Q54PX0|Y4251_DICDI Probable serine/threonine-protein kinase DD... 239 1e-67
sp|Q9S972|SD16_ARATH Receptor-like serine/threonine-protein kinas... 248 2e-67
sp|P29376|LTK_HUMAN Leukocyte tyrosine kinase receptor OS=Homo sa... 248 2e-67
sp|F8W3R9|ALK_DANRE ALK tyrosine kinase receptor OS=Danio rerio O... 253 2e-67
sp|O61122|SVKA_DICDI Serine/threonine-protein kinase svkA OS=Dict... 238 2e-67
sp|Q8VYA3|WAKLJ_ARATH Wall-associated receptor kinase-like 10 OS=... 246 2e-67
sp|C0LGG7|Y1534_ARATH Probable LRR receptor-like serine/threonine... 249 2e-67
sp|P20806|7LESS_DROVI Protein sevenless OS=Drosophila virilis OX=... 254 2e-67
sp|F4HRJ4|M3K3A_ARATH Mitogen-activated protein kinase kinase kin... 242 2e-67
sp|Q00993|UFO_MOUSE Tyrosine-protein kinase receptor UFO OS=Mus m... 248 2e-67
sp|P55146|TYRO3_RAT Tyrosine-protein kinase receptor TYRO3 OS=Rat... 248 2e-67
sp|Q9SXB4|Y1130_ARATH G-type lectin S-receptor-like serine/threon... 247 2e-67
sp|Q8L710|CRK17_ARATH Cysteine-rich receptor-like protein kinase ... 244 2e-67
sp|C0LGF4|FEI1_ARATH LRR receptor-like serine/threonine-protein k... 241 2e-67
sp|C0LGG9|Y5344_ARATH Probable LRR receptor-like serine/threonine... 250 2e-67
sp|Q86IX1|DST1_DICDI Serine/threonine-protein kinase dst1 OS=Dict... 245 3e-67
sp|O23082|CRK44_ARATH Cysteine-rich receptor-like protein kinase ... 235 3e-67
sp|O64793|Y1675_ARATH G-type lectin S-receptor-like serine/threon... 247 3e-67
sp|Q9LDN1|CRK33_ARATH Putative cysteine-rich receptor-like protei... 243 3e-67
sp|Q9C5S9|CRK6_ARATH Cysteine-rich receptor-like protein kinase 6... 243 3e-67
sp|P14617|INSRR_CAVPO Insulin receptor-related protein OS=Cavia p... 252 3e-67
sp|Q8RX80|CRK18_ARATH Cysteine-rich receptor-like protein kinase ... 243 3e-67
sp|Q9VZI2|ACK_DROME Activated Cdc42 kinase Ack OS=Drosophila mela... 250 3e-67
sp|P55144|TYRO3_MOUSE Tyrosine-protein kinase receptor TYRO3 OS=M... 248 3e-67
sp|Q9T058|Y4119_ARATH G-type lectin S-receptor-like serine/threon... 247 3e-67
sp|Q06418|TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3 OS=H... 248 3e-67
sp|C0LGQ7|Y4245_ARATH Probable LRR receptor-like serine/threonine... 248 3e-67
sp|Q9LZF8|PCRK2_ARATH Serine/threonine-protein kinase PCRK2 OS=Ar... 236 3e-67
sp|Q9T0J1|CRK26_ARATH Cysteine-rich receptor-like protein kinase ... 243 4e-67
sp|Q9LDM5|CRK31_ARATH Putative cysteine-rich receptor-like protei... 243 4e-67
sp|Q9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 OS=Homo ... 236 4e-67
sp|Q39086|SD17_ARATH Receptor-like serine/threonine-protein kinas... 246 4e-67
sp|P18160|SPLA_DICDI Dual specificity protein kinase splA OS=Dict... 253 4e-67
sp|H2L099|GCK1_CAEEL Germinal center kinase 1 OS=Caenorhabditis e... 242 5e-67
sp|Q9SN43|CIPKC_ARATH CBL-interacting serine/threonine-protein ki... 238 5e-67
sp|Q99KH8|STK24_MOUSE Serine/threonine-protein kinase 24 OS=Mus m... 236 5e-67
sp|Q9LDS6|CRK32_ARATH Putative cysteine-rich receptor-like protei... 242 6e-67
sp|Q8R4K2|IRAK4_MOUSE Interleukin-1 receptor-associated kinase 4 ... 236 6e-67
sp|Q54IP4|SHKB_DICDI Dual specificity protein kinase shkB OS=Dict... 242 6e-67
sp|Q8RZV7|MSP1_ORYSJ Leucine-rich repeat receptor protein kinase ... 251 6e-67
sp|Q9FN92|Y5597_ARATH Probable receptor-like protein kinase At5g5... 246 6e-67
sp|O81833|SD11_ARATH G-type lectin S-receptor-like serine/threoni... 246 6e-67
sp|Q54TH6|Y9863_DICDI Probable serine/threonine-protein kinase DD... 241 6e-67
sp|Q9LX66|HERK_ARATH Receptor-like protein kinase HERK 1 OS=Arabi... 246 7e-67
sp|C0LGT5|Y5169_ARATH Probable LRR receptor-like serine/threonine... 246 7e-67
sp|A7J1T2|M313A_XENLA Mitogen-activated protein kinase kinase kin... 248 8e-67
sp|Q5Z6X0|CIPKP_ORYSJ CBL-interacting protein kinase 25 OS=Oryza ... 238 8e-67
sp|O65405|CRK28_ARATH Cysteine-rich receptor-like protein kinase ... 243 8e-67
sp|Q6Z4U4|BAK1_ORYSJ LRR receptor kinase BAK1 OS=Oryza sativa sub... 241 8e-67
sp|B8BB68|BAK1_ORYSI LRR receptor kinase BAK1 OS=Oryza sativa sub... 241 8e-67
sp|O64777|Y1643_ARATH G-type lectin S-receptor-like serine/threon... 245 8e-67
sp|O24527|SIK1_ARATH Serine/threonine-protein kinase 1 OS=Arabido... 246 9e-67
sp|Q94F62|BAK1_ARATH BRASSINOSTEROID INSENSITIVE 1-associated rec... 241 9e-67
sp|Q9CAL8|PEK13_ARATH Proline-rich receptor-like protein kinase P... 243 9e-67
sp|Q8H199|CRK14_ARATH Cysteine-rich receptor-like protein kinase ... 241 1e-66
sp|Q7X8C5|WAKLB_ARATH Wall-associated receptor kinase-like 2 OS=A... 244 1e-66
sp|Q55EC7|GEFX_DICDI RasGEF domain-containing serine/threonine-pr... 247 1e-66
sp|Q9SIT1|TMK3_ARATH Receptor-like kinase TMK3 OS=Arabidopsis tha... 247 1e-66
sp|Q8L4H4|NORK_MEDTR Nodulation receptor kinase OS=Medicago trunc... 247 1e-66
sp|B0LT89|STK24_RAT Serine/threonine-protein kinase 24 OS=Rattus ... 235 1e-66
sp|Q8L7G3|CRK7_ARATH Cysteine-rich receptor-like protein kinase 7... 241 1e-66
sp|P48025|KSYK_MOUSE Tyrosine-protein kinase SYK OS=Mus musculus ... 240 1e-66
sp|Q9M2S4|LRKS4_ARATH L-type lectin-domain containing receptor ki... 242 1e-66
sp|O64770|Y1649_ARATH G-type lectin S-receptor-like serine/threon... 244 1e-66
sp|Q9SGY7|PEK11_ARATH Putative proline-rich receptor-like protein... 243 1e-66
sp|Q3E9X6|CRK21_ARATH Cysteine-rich receptor-like protein kinase ... 242 2e-66
sp|Q9LW83|CE101_ARATH G-type lectin S-receptor-like serine/threon... 245 2e-66
sp|Q8S9L6|CRK29_ARATH Cysteine-rich receptor-like protein kinase ... 241 2e-66
sp|O64768|RAF24_ARATH RAF-like serine/threonine-protein kinase 24... 249 2e-66
sp|O49339|PTI12_ARATH PTI1-like tyrosine-protein kinase 2 OS=Arab... 232 2e-66
sp|Q9ZP16|CRK11_ARATH Cysteine-rich receptor-like protein kinase ... 241 2e-66
sp|Q9SY95|Y1155_ARATH G-type lectin S-receptor-like serine/threon... 244 2e-66
sp|G5EGK5|CAM1_CAEEL Tyrosine-protein kinase receptor cam-1 OS=Ca... 246 2e-66
sp|Q9I7F7|ACKL_DROME Activated Cdc42 kinase-like OS=Drosophila me... 249 2e-66
sp|P53668|LIMK1_MOUSE LIM domain kinase 1 OS=Mus musculus OX=1009... 240 2e-66
sp|Q54RR9|Y9844_DICDI Probable serine/threonine-protein kinase DD... 250 2e-66
sp|Q8LKZ1|NORK_PEA Nodulation receptor kinase OS=Pisum sativum OX... 246 2e-66
sp|Q0WNY5|WAKLN_ARATH Wall-associated receptor kinase-like 18 OS=... 243 3e-66
sp|P14616|INSRR_HUMAN Insulin receptor-related protein OS=Homo sa... 249 3e-66
sp|F1QVU0|LTK_DANRE Tyrosine-protein kinase receptor OS=Danio rer... 249 3e-66
sp|C0LGL9|FEI2_ARATH LRR receptor-like serine/threonine-protein k... 238 3e-66
sp|A7J1T0|M313B_XENLA Mitogen-activated protein kinase kinase kin... 246 3e-66
sp|C0LGL4|Y2289_ARATH Probable LRR receptor-like serine/threonine... 244 4e-66
sp|O59790|ARK1_SCHPO Serine/threonine-protein kinase ark1 OS=Schi... 231 4e-66
sp|O61125|STK4_DICDI Serine/threonine-protein kinase 4 homolog A ... 234 4e-66
sp|Q94AG2|SERK1_ARATH Somatic embryogenesis receptor kinase 1 OS=... 239 4e-66
sp|P43405|KSYK_HUMAN Tyrosine-protein kinase SYK OS=Homo sapiens ... 239 4e-66
sp|P55245|EGFR_MACMU Epidermal growth factor receptor OS=Macaca m... 248 4e-66
sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sap... 248 4e-66
sp|Q9WTL4|INSRR_MOUSE Insulin receptor-related protein OS=Mus mus... 248 4e-66
sp|P70424|ERBB2_MOUSE Receptor tyrosine-protein kinase erbB-2 OS=... 248 4e-66
sp|C0LGV0|Y5487_ARATH Probable LRR receptor-like serine/threonine... 244 5e-66
sp|Q01279|EGFR_MOUSE Epidermal growth factor receptor OS=Mus musc... 248 5e-66
sp|Q7XV05|SERK2_ORYSJ LRR receptor kinase SERK2 OS=Oryza sativa s... 239 5e-66
sp|Q95UN8|M3KSL_DROME Mitogen-activated protein kinase kinase kin... 247 5e-66
sp|A9SY39|M3K1A_PHYPA Mitogen-activated protein kinase kinase kin... 242 5e-66
sp|P10533|RMIL_AVII1 Serine/threonine-protein kinase-transforming... 231 6e-66
sp|Q93ZS4|NIK3_ARATH Protein NSP-INTERACTING KINASE 3 OS=Arabidop... 239 6e-66
sp|Q9LXA5|LRK91_ARATH L-type lectin-domain containing receptor ki... 239 6e-66
sp|Q9LUT0|CARK1_ARATH Receptor-like cytoplasmic kinase 1 OS=Arabi... 230 6e-66
sp|Q6ZCZ2|BRL3_ORYSJ Brassinosteroid LRR receptor kinase BRL3 OS=... 247 6e-66
sp|Q60700|M3K12_MOUSE Mitogen-activated protein kinase kinase kin... 244 7e-66
sp|P53669|LIMK1_RAT LIM domain kinase 1 OS=Rattus norvegicus OX=1... 239 7e-66
sp|Q64716|INSRR_RAT Insulin receptor-related protein OS=Rattus no... 248 7e-66
sp|Q8BKG3|PTK7_MOUSE Inactive tyrosine-protein kinase 7 OS=Mus mu... 246 7e-66
sp|P00532|RAF_MSV36 Serine/threonine-protein kinase-transforming ... 229 8e-66
sp|Q23915|KINX_DICDI Probable serine/threonine-protein kinase kin... 246 8e-66
sp|P09208|INSR_DROME Insulin-like receptor OS=Drosophila melanoga... 249 8e-66
sp|Q12852|M3K12_HUMAN Mitogen-activated protein kinase kinase kin... 243 9e-66
sp|P06494|ERBB2_RAT Receptor tyrosine-protein kinase erbB-2 OS=Ra... 247 9e-66
sp|Q9ES74|NEK7_MOUSE Serine/threonine-protein kinase Nek7 OS=Mus ... 228 9e-66
sp|Q9LFH9|LRK81_ARATH L-type lectin-domain containing receptor ki... 240 9e-66
sp|Q9FJ55|CIPKJ_ARATH CBL-interacting serine/threonine-protein ki... 234 9e-66
sp|Q9V6K3|ROR2_DROME Tyrosine-protein kinase transmembrane recept... 240 1e-65
sp|Q60553|ERBB2_MESAU Receptor tyrosine-protein kinase erbB-2 OS=... 247 1e-65
sp|Q69JN6|BRL1_ORYSJ Brassinosteroid LRR receptor kinase BRL1 OS=... 247 1e-65
sp|O02466|ILPR_BRALA Insulin-like peptide receptor OS=Branchiosto... 247 1e-65
sp|Q9SXB5|Y1135_ARATH G-type lectin S-receptor-like serine/threon... 242 1e-65
sp|Q40541|NPK1_TOBAC Mitogen-activated protein kinase kinase kina... 239 1e-65
sp|Q9S9M3|WAKLC_ARATH Wall-associated receptor kinase-like 3 OS=A... 240 1e-65
sp|Q63796|M3K12_RAT Mitogen-activated protein kinase kinase kinas... 243 1e-65
sp|Q8TDX7|NEK7_HUMAN Serine/threonine-protein kinase Nek7 OS=Homo... 227 1e-65
sp|O65440|BAME3_ARATH Leucine-rich repeat receptor-like serine/th... 244 1e-65
sp|O22476|BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 OS=Ara... 246 1e-65
sp|D3ZBE5|NEK7_RAT Serine/threonine-protein kinase Nek7 OS=Rattus... 227 1e-65
sp|Q5MD89|VGFR3_DANRE Vascular endothelial growth factor receptor... 247 1e-65
sp|Q99JT2|STK26_MOUSE Serine/threonine-protein kinase 26 OS=Mus m... 231 1e-65
sp|Q86HG9|Y9871_DICDI Probable serine/threonine-protein kinase DD... 245 1e-65
sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens OX=9606... 238 1e-65
sp|P04626|ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 OS=... 247 1e-65
sp|Q9ZVR7|PSKR1_ARATH Phytosulfokine receptor 1 OS=Arabidopsis th... 244 1e-65
sp|P0CD62|LIMKB_DICDI Probable LIM domain-containing serine/threo... 244 1e-65
sp|Q8LPB4|PSKR1_DAUCA Phytosulfokine receptor 1 OS=Daucus carota ... 244 1e-65
sp|Q8BYG9|EPHAA_MOUSE Ephrin type-A receptor 10 OS=Mus musculus O... 244 1e-65
sp|Q96285|LRK55_ARATH L-type lectin-domain containing receptor ki... 238 1e-65
sp|Q7X996|CIPK2_ORYSJ CBL-interacting protein kinase 2 OS=Oryza s... 232 1e-65
sp|Q0WVM4|Y2239_ARATH Probable LRR receptor-like serine/threonine... 238 1e-65
sp|Q9ZRF9|RPK1_ARATH Probable LRR receptor-like serine/threonine-... 235 2e-65
sp|A0A2R6XIK6|PRAF_MARPO RAF-like serine/threonine-protein kinase... 247 2e-65
sp|Q8H1G6|PTI11_ARATH PTI1-like tyrosine-protein kinase 1 OS=Arab... 229 2e-65
sp|Q9FJ54|CIPKK_ARATH CBL-interacting serine/threonine-protein ki... 232 2e-65
sp|Q9FN94|RLK0_ARATH Receptor-like protein kinase At5g59670 OS=Ar... 242 2e-65
sp|Q9SA72|Y1357_ARATH Probable receptor-like protein kinase At1g3... 242 2e-65
sp|Q9P289|STK26_HUMAN Serine/threonine-protein kinase 26 OS=Homo ... 231 2e-65
sp|F4IB81|LYK3_ARATH LysM domain receptor-like kinase 3 OS=Arabid... 238 2e-65
sp|O04534|LRK51_ARATH Putative L-type lectin-domain containing re... 238 2e-65
sp|O22932|CIPKB_ARATH CBL-interacting serine/threonine-protein ki... 231 2e-65
sp|Q9FHG4|LRKS7_ARATH Probable L-type lectin-domain containing re... 238 2e-65
sp|Q8VYY5|NCRK_ARATH Receptor-like serine/threonine-protein kinas... 235 2e-65
sp|Q64725|KSYK_RAT Tyrosine-protein kinase SYK OS=Rattus norvegic... 237 2e-65
sp|Q54U31|SHKD_DICDI Dual specificity protein kinase shkD OS=Dict... 239 3e-65
sp|Q3SWY6|STK25_BOVIN Serine/threonine-protein kinase 25 OS=Bos t... 231 3e-65
sp|Q9SZD5|LRK59_ARATH L-type lectin-domain containing receptor ki... 238 3e-65
sp|C0LGQ5|GSO1_ARATH LRR receptor-like serine/threonine-protein k... 246 3e-65
sp|Q1HKZ5|M3K13_MOUSE Mitogen-activated protein kinase kinase kin... 243 3e-65
sp|Q9LDT0|CRK30_ARATH Putative cysteine-rich receptor-like protei... 238 3e-65
sp|Q9Z2W1|STK25_MOUSE Serine/threonine-protein kinase 25 OS=Mus m... 231 3e-65
sp|Q9M092|WAKLM_ARATH Wall-associated receptor kinase-like 17 OS=... 240 3e-65
sp|Q8W1D5|CIPKP_ARATH CBL-interacting serine/threonine-protein ki... 233 3e-65
sp|Q9XIC7|SERK2_ARATH Somatic embryogenesis receptor kinase 2 OS=... 236 3e-65
sp|Q9FXF2|RKF1_ARATH Probable LRR receptor-like serine/threonine-... 243 3e-65
sp|P00531|MIL_AVIMH Serine/threonine-protein kinase-transforming ... 229 3e-65
sp|Q942F3|BRI1_ORYSJ Brassinosteroid LRR receptor kinase BRI1 OS=... 244 4e-65
sp|Q9LN59|WAKLK_ARATH Putative wall-associated receptor kinase-li... 240 4e-65
sp|P23437|CDK2_XENLA Cyclin-dependent kinase 2 OS=Xenopus laevis ... 226 4e-65
sp|Q8VDG6|M3K21_MOUSE Mitogen-activated protein kinase kinase kin... 243 4e-65
sp|Q5JZY3|EPHAA_HUMAN Ephrin type-A receptor 10 OS=Homo sapiens O... 243 4e-65
sp|O00506|STK25_HUMAN Serine/threonine-protein kinase 25 OS=Homo ... 230 4e-65
sp|Q7G768|BRL2_ORYSJ Brassinosteroid LRR receptor kinase BRL2 OS=... 244 5e-65
sp|Q9M1Z9|LRK58_ARATH Putative L-type lectin-domain containing re... 236 5e-65
sp|Q00655|KSYK_PIG Tyrosine-protein kinase SYK OS=Sus scrofa OX=9... 236 5e-65
sp|Q9S9M2|WAKLD_ARATH Wall-associated receptor kinase-like 4 OS=A... 239 5e-65
sp|Q54R58|YTYK2_DICDI Probable tyrosine-protein kinase DDB_G02833... 241 6e-65
sp|C0LGN2|Y3148_ARATH Probable leucine-rich repeat receptor-like ... 243 6e-65
sp|Q9SKG5|SERK4_ARATH Somatic embryogenesis receptor kinase 4 OS=... 235 7e-65
sp|Q5E9L6|STK4_BOVIN Serine/threonine-protein kinase 4 OS=Bos tau... 231 7e-65
sp|O18735|ERBB2_CANLF Receptor tyrosine-protein kinase erbB-2 OS=... 244 7e-65
sp|O80623|Y2393_ARATH Probable receptor-like protein kinase At2g3... 239 7e-65
sp|P27966|RMIL_AVEVR Serine/threonine-protein kinase-transforming... 230 7e-65
sp|Q39202|RLK1_ARATH G-type lectin S-receptor-like serine/threoni... 240 8e-65
sp|P43298|TMK1_ARATH Receptor protein kinase TMK1 OS=Arabidopsis ... 241 8e-65
sp|C0LGG6|Y5189_ARATH Probable LRR receptor-like protein kinase A... 240 8e-65
sp|Q9S9M5|WAKLA_ARATH Wall-associated receptor kinase-like 1 OS=A... 238 8e-65
sp|Q9LFV3|CRLK2_ARATH Calcium/calmodulin-regulated receptor-like ... 229 9e-65
sp|Q9LEU7|CIPK5_ARATH CBL-interacting serine/threonine-protein ki... 230 9e-65
sp|A8R7E6|CERK1_ARATH Chitin elicitor receptor kinase 1 OS=Arabid... 235 9e-65
sp|Q9FX99|Y1497_ARATH Probable receptor-like protein kinase At1g4... 236 9e-65
sp|O80719|Y2706_ARATH Probable receptor-like protein kinase At2g4... 227 9e-65
sp|Q1PEM5|PERK3_ARATH Proline-rich receptor-like protein kinase P... 232 9e-65
sp|Q86AE1|Y9853_DICDI Probable serine/threonine-protein kinase DD... 232 1e-64
sp|O43283|M3K13_HUMAN Mitogen-activated protein kinase kinase kin... 241 1e-64
sp|Q9LIG2|RLK6_ARATH Receptor-like protein kinase At3g21340 OS=Ar... 240 1e-64
sp|Q13308|PTK7_HUMAN Inactive tyrosine-protein kinase 7 OS=Homo s... 243 1e-64
sp|Q9JI11|STK4_MOUSE Serine/threonine-protein kinase 4 OS=Mus mus... 231 1e-64
sp|Q9FZB8|Y5181_ARATH Probable LRR receptor-like serine/threonine... 240 1e-64
sp|P04412|EGFR_DROME Epidermal growth factor receptor OS=Drosophi... 244 1e-64
sp|Q13043|STK4_HUMAN Serine/threonine-protein kinase 4 OS=Homo sa... 231 1e-64
sp|Q9LV48|PERK1_ARATH Proline-rich receptor-like protein kinase P... 235 1e-64
sp|A4K2Y1|STK4_CHLAE Serine/threonine-protein kinase 4 OS=Chloroc... 231 1e-64
sp|A4K2T0|STK4_MACMU Serine/threonine-protein kinase 4 OS=Macaca ... 231 1e-64
sp|Q8VYT3|Y4052_ARATH Probable LRR receptor-like serine/threonine... 235 1e-64
sp|A4K2M3|STK4_PAPAN Serine/threonine-protein kinase 4 OS=Papio a... 231 1e-64
sp|Q9SX31|PERK9_ARATH Proline-rich receptor-like protein kinase P... 236 1e-64
sp|O23081|CRK41_ARATH Cysteine-rich receptor-like protein kinase ... 236 1e-64
sp|Q9ZUE0|PEK12_ARATH Proline-rich receptor-like protein kinase P... 237 1e-64
sp|Q8RY17|WAKLI_ARATH Wall-associated receptor kinase-like 22 OS=... 237 1e-64
sp|Q9FNE1|CRK42_ARATH Cysteine-rich receptor-like protein kinase ... 235 1e-64
sp|Q8RY67|WAKLO_ARATH Wall-associated receptor kinase-like 14 OS=... 236 2e-64
sp|P83104|M3K7L_DROME Putative mitogen-activated protein kinase k... 227 2e-64
sp|Q00526|CDK3_HUMAN Cyclin-dependent kinase 3 OS=Homo sapiens OX... 224 2e-64
sp|Q852Q0|OSK3_ORYSJ Serine/threonine protein kinase OSK3 OS=Oryz... 231 2e-64
sp|A2XFF4|OSK3_ORYSI Serine/threonine protein kinase OSK3 OS=Oryz... 231 2e-64
sp|P18161|SPLB_DICDI Dual specificity protein kinase splB OS=Dict... 243 2e-64
sp|P05625|RAF1_CHICK RAF proto-oncogene serine/threonine-protein ... 235 2e-64
sp|O81905|SD18_ARATH Receptor-like serine/threonine-protein kinas... 239 2e-64
sp|Q9C821|PEK15_ARATH Proline-rich receptor-like protein kinase P... 231 2e-64
sp|Q54XX5|Y9849_DICDI Probable serine/threonine-protein kinase DD... 239 2e-64
sp|O81069|Y2899_ARATH Probable leucine-rich repeat receptor-like ... 239 2e-64
sp|C0LGI2|Y1677_ARATH Probable LRR receptor-like serine/threonine... 240 2e-64
sp|O64782|SD129_ARATH G-type lectin S-receptor-like serine/threon... 238 2e-64
sp|Q8T2I8|SEPA_DICDI Serine/threonine-protein kinase sepA OS=Dict... 242 2e-64
sp|Q9FZB1|Y5188_ARATH Probable LRR receptor-like serine/threonine... 239 2e-64
sp|Q5E9Y0|CDK2_BOVIN Cyclin-dependent kinase 2 OS=Bos taurus OX=9... 223 2e-64
sp|Q6H7U5|CIPKQ_ORYSJ CBL-interacting protein kinase 26 OS=Oryza ... 230 2e-64
Sequences not found previously or not previously below threshold:
>sp|P29597|TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2
OS=Homo sapiens OX=9606 GN=TYK2 PE=1 SV=3
Length=1187
Score = 1630 bits (4220), Expect = 0.0, Method: Composition-based stats.
Identities = 1187/1187 (100%), Positives = 1187/1187 (100%), Gaps = 0/1187 (0%)
Query 1 MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI 60
MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI
Sbjct 1 MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI 60
Query 61 AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREP 120
AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREP
Sbjct 61 AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREP 120
Query 121 AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFK 180
AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFK
Sbjct 121 AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFK 180
Query 181 NESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRR 240
NESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRR
Sbjct 181 NESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRR 240
Query 241 FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP 300
FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP
Sbjct 241 FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP 300
Query 301 TDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHK 360
TDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHK
Sbjct 301 TDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHK 360
Query 361 AVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLV 420
AVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLV
Sbjct 361 AVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLV 420
Query 421 DGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP 480
DGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP
Sbjct 421 DGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP 480
Query 481 YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA 540
YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA
Sbjct 481 YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA 540
Query 541 GDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTR 600
GDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTR
Sbjct 541 GDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTR 600
Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660
TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS
Sbjct 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS
Sbjct 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780
ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA
Sbjct 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840
PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ
Sbjct 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI
Sbjct 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII
Sbjct 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI
Sbjct 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY
Sbjct 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC
Sbjct 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC 1187
PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC
Sbjct 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC 1187
>sp|Q9R117|TYK2_MOUSE Non-receptor tyrosine-protein kinase TYK2
OS=Mus musculus OX=10090 GN=Tyk2 PE=1 SV=3
Length=1184
Score = 1498 bits (3879), Expect = 0.0, Method: Composition-based stats.
Identities = 939/1177 (80%), Positives = 1023/1177 (87%), Gaps = 10/1177 (1%)
Query 12 SKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCF 71
SK G AQP+ G L VLLHW GP GGEPWVTFS++SLTAEEVCIHIAHKVGITPPC
Sbjct 17 SKADGTEAQPLVPTGCLMVLLHWPGPEGGEPWVTFSQTSLTAEEVCIHIAHKVGITPPCL 76
Query 72 NLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTE 131
NLFAL++AQA+VWLPPNHIL+ +D + LYFR+RFYFRNWHGMNP+EPAVYRCG PG E
Sbjct 77 NLFALYNAQAKVWLPPNHILDTSQD--MNLYFRMRFYFRNWHGMNPQEPAVYRCGFPGAE 134
Query 132 ASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHL 191
SSD+ QG+QLLD ASFEYLFEQGKHEF+NDV SL +LS+EEEIHHFKNESLGMAFLHL
Sbjct 135 TSSDRAEQGVQLLDSASFEYLFEQGKHEFMNDVVSLRDLSSEEEIHHFKNESLGMAFLHL 194
Query 192 CHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLS 251
CHLAL G+PLEE+A++ SFK+CIP SFR+HIRQH+ LTRLRL VFRRFLR F+PG LS
Sbjct 195 CHLALSRGVPLEEMAREISFKNCIPHSFRQHIRQHNVLTRLRLHRVFRRFLRAFRPGHLS 254
Query 252 QQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGP 311
QQ+VMVKYLATLERLAPRFG+ER+PVCHL +LAQ E +PCYI++SG DPGPE +GP
Sbjct 255 QQVVMVKYLATLERLAPRFGSERIPVCHLEVLAQPERDPCYIQNSGQTAGDPGPELPSGP 314
Query 312 PTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPRE 371
PTHEVLVTGTGGIQW P++ +E G+S NP S GKK KA KA + P+E
Sbjct 315 PTHEVLVTGTGGIQWHPLQ----TQESERGNSRGNPHGSRSGKKPKAPKAGEHLTESPQE 370
Query 372 PLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSS 431
P W YFCDF+DI+HVVLKE V IH QDNKCL L L S+A ALSFV+LVDGYFRLTADSS
Sbjct 371 PPWTYFCDFQDISHVVLKERRVHIHLQDNKCLLLCLCSQAEALSFVALVDGYFRLTADSS 430
Query 432 HYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRS 491
HYLCHEVAPPRLV SI++GIHGPL++PFVQAKL PEDGLYLI WSTSH +RLILTVA R+
Sbjct 431 HYLCHEVAPPRLVTSIQNGIHGPLMDPFVQAKLWPEDGLYLIQWSTSHLHRLILTVAHRN 490
Query 492 QA-PDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRC 550
A +G + LRLRKFPI QQ GAFVL+GWGRSF S+ +L ALQGC LRAGDDCF L C
Sbjct 491 PAFSNGPRGLRLRKFPITQQPGAFVLDGWGRSFASLGDLRLALQGCSLRAGDDCFPLHHC 550
Query 551 CLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRV 610
CLP+P E SNL+IMRG+RA R LNLSQLSFHRV Q EITQLSHLGQGTRTNVYEG LRV
Sbjct 551 CLPRPREISNLVIMRGSRAHTRPLNLSQLSFHRVHQDEITQLSHLGQGTRTNVYEGLLRV 610
Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670
G P+EGK+D+ P PG GQ+LRVVLKVLDPSHHDIALAFYETASLMSQVSH HL
Sbjct 611 GG---PDEGKVDNGCPPEPGGTSGQQLRVVLKVLDPSHHDIALAFYETASLMSQVSHMHL 667
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730
AF+HGVCVRG ENI+VTE+VEHGPLDVWLRR+RG VPM WKMVVAQQLASALSYLE+KNL
Sbjct 668 AFLHGVCVRGSENIIVTEFVEHGPLDVWLRRQRGQVPMTWKMVVAQQLASALSYLEDKNL 727
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANS 790
VHGNVCGRNILLARLGL EGT+PFIKLSDPGVG GALSREERVERIPW APECL GG +S
Sbjct 728 VHGNVCGRNILLARLGLEEGTNPFIKLSDPGVGQGALSREERVERIPWTAPECLSGGTSS 787
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLT 850
L TA D WGFGATLLEICFDGEAPLQ R PSEKE FY ++H+LPEPS P+LATLT QCLT
Sbjct 788 LGTATDMWGFGATLLEICFDGEAPLQGRGPSEKERFYTKKHQLPEPSSPELATLTRQCLT 847
Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910
YEP QRPSFRTILRDLTRLQP NL VN DSPASDPTVFHKRYLKKIRDLGEGHFGK
Sbjct 848 YEPAQRPSFRTILRDLTRLQPQNLVGTSAVNSDSPASDPTVFHKRYLKKIRDLGEGHFGK 907
Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970
VSLYCYDPTNDGTGEMVAVKALK CGPQ RSGW++EI+ILRTLYHEHI+KYKGCCEDQG
Sbjct 908 VSLYCYDPTNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVKYKGCCEDQG 967
Query 971 EKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030
EKS+QLVMEYVPLGSLRDYLPRH +GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL
Sbjct 968 EKSVQLVMEYVPLGSLRDYLPRHCVGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1027
Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE KFYYASDVWSFGVT
Sbjct 1028 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSFGVT 1087
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
LYELLT+CDS+QSP KF ELIG QGQMTVLRLTELLERGERLPRPD+CPCE+YHLMKN
Sbjct 1088 LYELLTYCDSNQSPHMKFTELIGHTQGQMTVLRLTELLERGERLPRPDRCPCEIYHLMKN 1147
Query 1151 CWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC 1187
CWETEASFRPTF+NL+PIL+T EKYQGQ PSVFSVC
Sbjct 1148 CWETEASFRPTFQNLVPILQTAQEKYQGQVPSVFSVC 1184
>sp|O12990|JAK1_DANRE Tyrosine-protein kinase JAK1 OS=Danio rerio
OX=7955 GN=jak1 PE=1 SV=1
Length=1153
Score = 1224 bits (3167), Expect = 0.0, Method: Composition-based stats.
Identities = 526/1171 (45%), Positives = 724/1171 (62%), Gaps = 63/1171 (5%)
Query 23 AAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQ 82
AM GL++ + A + F ++ TAE++C+ A + I+P C NLFAL++
Sbjct 29 TAMKGLEIHFYLADTHQ----LEFFKACYTAEDLCVEAAKRCRISPLCHNLFALYEESQD 84
Query 83 VWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRC--GPPGTEASSDQTAQG 140
+W PNH+ ++ + S+ L++R+RFYF NWHG + E V+R + +S +T +G
Sbjct 85 LWYAPNHVFKVTDETSIKLHYRMRFYFTNWHGTSEIESPVWRHTLSKQKSVLNSQKTTEG 144
Query 141 MQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGI 200
LLD AS +YLF QG+++F+ ++ + T+EE H +NE LGMA L + H A + +
Sbjct 145 TPLLDAASLDYLFAQGQYDFLRGLSPVRPTQTDEEHHEIENECLGMAVLAITHHAKSNNL 204
Query 201 PLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQ-----QMV 255
PL +TS+K IP S R I+Q + LTR+R+ NVF+ FL +F + +
Sbjct 205 PLSGAGAETSYKRFIPDSLNRTIKQRNFLTRIRISNVFKNFLNEFNSKTIQDSNIGLYDL 264
Query 256 MVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHE 315
VKYL+TLE L G E +L++ ++EG P A P ++ G +E
Sbjct 265 KVKYLSTLETLTQGVGREIFKPKNLKVTGESEGSP--------AQMLPLGDNGMG---YE 313
Query 316 VLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVG--QPADRPREPL 373
V V GT GI W P + K K+ K G Q D+ ++
Sbjct 314 VQVYGTTGISW---------------RRKPAPNQLILKDKPKSKKIKGDKQWNDKKKDSG 358
Query 374 WAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHY 433
W F DF +ITH+V+K+ CV+I+RQDNK +EL L R AALSF +LVDGYFRLT D+ HY
Sbjct 359 WTLFSDFHEITHIVIKDCCVTIYRQDNKTMELDLFYRDAALSFAALVDGYFRLTVDAHHY 418
Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILTV-AQ 489
LC +VAP +V ++ +G HGP+ + KLR E +G Y++ WS + +I+TV
Sbjct 419 LCTDVAPSSVVQNLENGCHGPICTEYAIHKLRQEGNEEGTYVLRWSCTEYNFIIMTVVCI 478
Query 490 RSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRR 549
+ + + F IE + L G P+++EL LQG LLR + F LRR
Sbjct 479 ELDLCESRPVPQYKNFQIETSPQGYRLYGTDTFRPTLKELLEHLQGQLLRTDNLRFQLRR 538
Query 550 CCLPQPGETSNLIIMRGARAS--PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
CC PQP E SNL++M R + +SQLSF R+ ++EI Q HLG+GTRTN+Y G
Sbjct 539 CCPPQPREISNLLVMTTDREPVPQKKTQVSQLSFDRILKEEIVQGEHLGRGTRTNIYAGI 598
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667
L+ + + + G QE++VVLKVL H DI+LAF+ETAS+M Q+SH
Sbjct 599 LKPKSDDEDDLG------------GYSQEVKVVLKVLGSGHRDISLAFFETASMMRQISH 646
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
H A ++GVCVR ENIMV E+V++GPLD+++RR+ + AWK VA+QLASALSYLE+
Sbjct 647 KHTALLYGVCVRHQENIMVEEFVQYGPLDLFMRRQTTPLSTAWKFQVAKQLASALSYLED 706
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGG 787
K +VHG VC +NIL+AR GL PFIKLSDPG+ + LSREE V+RIPW+APEC+
Sbjct 707 KKMVHGYVCSKNILVARDGLDGEGGPFIKLSDPGIPITVLSREECVDRIPWIAPECVKDT 766
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ 847
AN L+ A DKW FG TL EIC++GE PL+ + SEKE FY Q +L P C +LA L +
Sbjct 767 AN-LTIAADKWSFGTTLWEICYNGEIPLKDKKLSEKERFYAAQCQLATPDCDELAKLMTH 825
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
C+TY+P QR FR I+ + + DPTVF KR+LKKIRDLGEGH
Sbjct 826 CMTYDPRQRLFFRAIV---RDIVMVEKQNPSIQPVPMLEVDPTVFEKRFLKKIRDLGEGH 882
Query 908 FGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
FGKV L YDP D TGE+VAVK+LK + + + +EI ILR LYHE+I+KYKG C
Sbjct 883 FGKVELCRYDPRGDRTGELVAVKSLKPENREEQSNNLWREIHILRELYHENIVKYKGICN 942
Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
++G +S++L+ME++P GSL++YLPR+ I L L ++ QIC+GM YL +++YIHRDLA
Sbjct 943 EEGGRSIKLIMEFLPAGSLKEYLPRNKAHINLKTLHNYSVQICQGMDYLGSRNYIHRDLA 1002
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
ARNVL++N+ VKIGDFGL K++ + YY V++D DSPVFWYAPECL KFY ASDVW
Sbjct 1003 ARNVLVENEGTVKIGDFGLTKSIKDNEGYYTVKDDLDSPVFWYAPECLIHCKFYRASDVW 1062
Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
SFGVT+YELLT+CD+S SP + FL+LIG GQMTV RL ++LE G+RLPRPD C ++Y
Sbjct 1063 SFGVTMYELLTYCDASCSPMSVFLKLIGPTHGQMTVTRLVKVLEEGKRLPRPDDCSEQLY 1122
Query 1146 HLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
+LM+ CWE R F++LI + + +
Sbjct 1123 NLMRRCWEATPEKRIDFKSLIANFQQMLDNL 1153
Score = 122 bits (305), Expect = 1e-26, Method: Composition-based stats.
Identities = 76/416 (18%), Positives = 144/416 (35%), Gaps = 59/416 (14%)
Query 798 WGFGA---TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP--EPSCPQLATLTS----QC 848
+ F +E+ P+ + E + +RL + P L L Q
Sbjct 468 YNFIIMTVVCIELDLCESRPVPQYKNFQIET-SPQGYRLYGTDTFRPTLKELLEHLQGQL 526
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
L + + R + + + + + K + H
Sbjct 527 LRTDNLRFQLRRCCPPQPREISNLLVMTTDREPVPQKKTQVSQLSFDRILKEEIVQGEHL 586
Query 909 GK-----VSLYCYDPTNDGTGE--------MVAVKALKADCGPQHRSGWKQEIDILRTLY 955
G+ + P +D + V +K L + + ++ ++R +
Sbjct 587 GRGTRTNIYAGILKPKSDDEDDLGGYSQEVKVVLKVLGSGHRDISLAFFET-ASMMRQIS 645
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLF--AQQICEGMAY 1013
H+H G C E +V E+V G L ++ R + L+ F A+Q+ ++Y
Sbjct 646 HKHTALLYGVCVRHQEN--IMVEEFVQYGPLDLFMRRQTTPLSTAWKFQVAKQLASALSY 703
Query 1014 LHAQHYIHRDLAARNVLLDNDRL-------VKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
L + +H + ++N+L+ D L +K+ D G+ RE+ +
Sbjct 704 LEDKKMVHGYVCSKNILVARDGLDGEGGPFIKLSDPGI-------PITVLSREECVDRIP 756
Query 1067 WYAPECLKEY-KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
W APEC+K+ A+D WSFG TL+E+ C + + P +
Sbjct 757 WIAPECVKDTANLTIAADKWSFGTTLWEI---CYNGEIPLKD-----------KKLSEKE 802
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
+L PD E+ LM +C + R F ++ + V ++ P
Sbjct 803 RFYAAQCQLATPDC--DELAKLMTHCMTYDPRQRLFFRAIVRDIVMVEKQNPSIQP 856
>sp|P23458|JAK1_HUMAN Tyrosine-protein kinase JAK1 OS=Homo sapiens
OX=9606 GN=JAK1 PE=1 SV=2
Length=1154
Score = 1219 bits (3155), Expect = 0.0, Method: Composition-based stats.
Identities = 529/1180 (45%), Positives = 730/1180 (62%), Gaps = 60/1180 (5%)
Query 10 RGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPP 69
R SK A G++V+ + + + TAEE+CI A I+P
Sbjct 20 RSSKK--TEVNLEAPEPGVEVIFYLSDREP----LRLGSGEYTAEELCIRAAQACRISPL 73
Query 70 CFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPG 129
C NLFAL+D ++W PN + + SL L++R+RFYF NWHG N E +V+R P
Sbjct 74 CHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTNDNEQSVWRHSPKK 133
Query 130 TEASSDQT--AQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMA 187
+ ++ LLD +S EYLF QG+++ V +A + + TE++ H +NE LGMA
Sbjct 134 QKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQDGHDIENECLGMA 193
Query 188 FLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQP 247
L + H A+ + L E+ K S+K IP + + IRQ + LTR+R+ NVF+ FL++F
Sbjct 194 VLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFNN 253
Query 248 GRLSQ-----QMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTD 302
+ + VKYLATLE L +G E L + ++ E + D G
Sbjct 254 KTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMNWFHSNDGGNVL-- 311
Query 303 PGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAV 362
+EV+VTG GIQW + + + S + K HK
Sbjct 312 ----------YYEVMVTGNLGIQW--------RHKPNVVSVEKEKNKLKRKKLENKHKK- 352
Query 363 GQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDG 422
+ ++ RE W F F +ITH+V+KE VSI++QDNK +EL L S ALSFVSLVDG
Sbjct 353 DEEKNKIREE-WNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDG 411
Query 423 YFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSH 479
YFRLTAD+ HYLC +VAPP +V +I++G HGP+ + KLR E +G+Y++ WS +
Sbjct 412 YFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTD 471
Query 480 PYRLILTVA--QRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCL 537
+++TV ++S+ G Q + + F IE Q G + L G RSFPS+ +L + L+ +
Sbjct 472 FDNILMTVTCFEKSEQVQGAQK-QFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQI 530
Query 538 LRAGDDCFSLRRCCLPQPGETSNLII-MRGARASPRTLNLSQLSFHRVDQKEITQLSHLG 596
LR + F L+RCC P+P E SNL++ + A+ +SQLSF R+ +K++ Q HLG
Sbjct 531 LRTDNISFMLKRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLG 590
Query 597 QGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFY 656
+GTRT++Y G L + G ++++V+LKVLDPSH DI+LAF+
Sbjct 591 RGTRTHIYSGTLMDYKDDE--------------GTSEEKKIKVILKVLDPSHRDISLAFF 636
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
E AS+M QVSH H+ +++GVCVR ENIMV E+VE GPLD+++ R+ + WK VA+
Sbjct 637 EAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAK 696
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI 776
QLASALSYLE+K+LVHGNVC +N+LLAR G+ PFIKLSDPG+ + LSR+E +ERI
Sbjct 697 QLASALSYLEDKDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGIPITVLSRQECIERI 756
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836
PW+APEC+ N LS A DKW FG TL EIC++GE PL+ ++ EKE FY+ + R P
Sbjct 757 PWIAPECVEDSKN-LSVAADKWSFGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTP 815
Query 837 SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896
SC +LA L ++C+ Y+P QRP FR I+RD+ +L+ N V P + F KR+
Sbjct 816 SCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQNPDIVSEKKPATEVDPTH-FEKRF 874
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
LK+IRDLGEGHFGKV L YDP D TGE VAVK+LK + G H + K+EI+ILR LYH
Sbjct 875 LKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYH 934
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYL 1014
E+I+KYKG C + G ++L+ME++P GSL++YLP++ I L Q L +A QIC+GM YL
Sbjct 935 ENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYL 994
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
++ Y+HRDLAARNVL++++ VKIGDFGL KA+ EYY V++D DSPVFWYAPECL
Sbjct 995 GSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLM 1054
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ KFY ASDVWSFGVTL+ELLT+CDS SP FL++IG GQMTV RL L+ G+RL
Sbjct 1055 QSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRL 1114
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
P P CP EVY LM+ CWE + S R +F+NLI + + +
Sbjct 1115 PCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK 1154
Score = 150 bits (380), Expect = 2e-35, Method: Composition-based stats.
Identities = 77/358 (22%), Positives = 137/358 (38%), Gaps = 55/358 (15%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
+ +C +P + + L A K+ L + L
Sbjct 539 MLKRCCQPKPREISNL---------LVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHL 589
Query 904 GEG---HFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS---GWKQEIDILRTLYHE 957
G G H +L Y ++GT E +K + P HR + + ++R + H+
Sbjct 590 GRGTRTHIYSGTLMDYKD-DEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHK 648
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015
HI+ G C E +V E+V G L ++ R S + A+Q+ ++YL
Sbjct 649 HIVYLYGVCVRDVEN--IMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLE 706
Query 1016 AQHYIHRDLAARNVLLDNDRL-------VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+ +H ++ +N+LL + + +K+ D G+ R++ + W
Sbjct 707 DKDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGI-------PITVLSRQECIERIPWI 759
Query 1069 APECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APEC+++ K A+D WSFG TL+E+ C + + P T++
Sbjct 760 APECVEDSKNLSVAADKWSFGTTLWEI---CYNGEIPLKD-----------KTLIEKERF 805
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
E R P E+ LM C + + RP F ++ + + E Q P + S
Sbjct 806 YESRCRPVTPSC--KELADLMTRCMNYDPNQRPFFRAIMRDINKLEE----QNPDIVS 857
>sp|P52332|JAK1_MOUSE Tyrosine-protein kinase JAK1 OS=Mus musculus
OX=10090 GN=Jak1 PE=1 SV=1
Length=1153
Score = 1219 bits (3153), Expect = 0.0, Method: Composition-based stats.
Identities = 526/1173 (45%), Positives = 731/1173 (62%), Gaps = 59/1173 (5%)
Query 17 DGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFAL 76
+ + G++V + + TAEE+CI A + I+P C NLFAL
Sbjct 25 TEVKQVVPEPGVEVTFYLLDREP----LRLGSGEYTAEELCIRAAQECSISPLCHNLFAL 80
Query 77 FDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQ 136
+D ++W PN I+ + SL L++R+RFYF NWHG N E +V+R P + ++
Sbjct 81 YDESTKLWYAPNRIITVDDKTSLRLHYRMRFYFTNWHGTNDNEQSVWRHSPKKQKNGYEK 140
Query 137 T--AQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHL 194
+ LLD +S EYLF QG+++ + +A + + TE++ H +NE LGMA L + H
Sbjct 141 KRVPEATPLLDASSLEYLFAQGQYDLIKCLAPIRDPKTEQDGHDIENECLGMAVLAISHY 200
Query 195 ALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQ-- 252
A+ + L E+ K S+K IP + + IRQ + LTR+R+ NVF+ FL++F +
Sbjct 201 AMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFNNKTICDSS 260
Query 253 -QMVMVKYLATLER--LAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAA 309
+ VKYLATLE L +G E L + ++ E C+ DSG
Sbjct 261 VHDLKVKYLATLETSTLTKHYGAEIFETSMLLISSENELSRCHSNDSGNV---------- 310
Query 310 GPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRP 369
+EV+VTG GIQW ++ N + + + K K ++
Sbjct 311 ---LYEVMVTGNLGIQW---RQKPNVVPVEKEKNKLKRKKLEYNKHKK-----DDERNKL 359
Query 370 REPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTAD 429
RE W F F +ITH+V+KE VSI++QDNK +EL L SR ALSFVSLVDGYFRLTAD
Sbjct 360 REE-WNNFSYFPEITHIVIKESVVSINKQDNKNMELKLSSREEALSFVSLVDGYFRLTAD 418
Query 430 SSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILT 486
+ HYLC +VAPP +V +I++G HGP+ + KLR E +G+Y++ WS + +++T
Sbjct 419 AHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMT 478
Query 487 VA--QRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDC 544
V ++S+ G + + + F IE Q G + L G FPS+R+L L+ +LR +
Sbjct 479 VTCFEKSEVLGGQK--QFKNFQIEVQKGRYSLHGSMDHFPSLRDLMNHLKKQILRTDNIS 536
Query 545 FSLRRCCLPQPGETSNLII-MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603
F L+RCC P+P E SNL++ + A+ ++SQLSF R+ +K+I Q HLG+GTRT++
Sbjct 537 FVLKRCCQPKPREISNLLVATKKAQEWQPVYSMSQLSFDRILKKDIIQGEHLGRGTRTHI 596
Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663
Y G L + G ++++V+LKVLDPSH DI+LAF+E AS+M
Sbjct 597 YSGTLLDYKDEE--------------GIAEEKKIKVILKVLDPSHRDISLAFFEAASMMR 642
Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723
QVSH H+ +++GVCVR ENIMV E+VE GPLD+++ R+ + WK VA+QLASALS
Sbjct 643 QVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDALTTPWKFKVAKQLASALS 702
Query 724 YLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPEC 783
YLE+K+LVHGNVC +N+LLAR G+ PFIKLSDPG+ + L+R+E +ERIPW+APEC
Sbjct 703 YLEDKDLVHGNVCTKNLLLAREGIDSDIGPFIKLSDPGIPVSVLTRQECIERIPWIAPEC 762
Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT 843
+ N LS A DKW FG TL EIC++GE PL+ ++ EKE FY+ + R PSC +LA
Sbjct 763 VEDSKN-LSVAADKWSFGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELAD 821
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
L ++C+ Y+P QRP FR I+RD+ +L+ N V P + F KR+LK+IRDL
Sbjct 822 LMTRCMNYDPNQRPFFRAIMRDINKLEEQNPDIVSEKQPTTEVDPTH-FEKRFLKRIRDL 880
Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963
GEGHFGKV L YDP D TGE VAVK+LK + G H + K+EI+ILR LYHE+I+KYK
Sbjct 881 GEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYK 940
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G C + G ++L+ME++P GSL++YLP++ I L Q L +A QIC+GM YL ++ Y+H
Sbjct 941 GICMEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAIQICKGMDYLGSRQYVH 1000
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RDLAARNVL++++ VKIGDFGL KA+ EYY V++D DSPVFWYAPECL + KFY A
Sbjct 1001 RDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIA 1060
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
SDVWSFGVTL+ELLT+CDS SP FL++IG GQMTV RL + L+ G+RLP P CP
Sbjct 1061 SDVWSFGVTLHELLTYCDSDFSPMALFLKMIGPTHGQMTVTRLVKTLKEGKRLPCPPNCP 1120
Query 1142 CEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
EVY LM+ CWE + S R TF+NLI + + +
Sbjct 1121 DEVYQLMRKCWEFQPSNRTTFQNLIEGFEALLK 1153
Score = 148 bits (373), Expect = 1e-34, Method: Composition-based stats.
Identities = 73/357 (20%), Positives = 132/357 (37%), Gaps = 53/357 (15%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
+ +C +P + + L A K+ + + L
Sbjct 538 VLKRCCQPKPREISNL---------LVATKKAQEWQPVYSMSQLSFDRILKKDIIQGEHL 588
Query 904 GEGHFGKVSLYCYDPTNDGTG--EMVAVKALKADCGPQHRS---GWKQEIDILRTLYHEH 958
G G + D G E +K + P HR + + ++R + H+H
Sbjct 589 GRGTRTHIYSGTLLDYKDEEGIAEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKH 648
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHA 1016
I+ G C E +V E+V G L ++ R S + A+Q+ ++YL
Sbjct 649 IVYLYGVCVRDVEN--IMVEEFVEGGPLDLFMHRKSDALTTPWKFKVAKQLASALSYLED 706
Query 1017 QHYIHRDLAARNVLLDNDRL-------VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ +H ++ +N+LL + + +K+ D G+ R++ + W A
Sbjct 707 KDLVHGNVCTKNLLLAREGIDSDIGPFIKLSDPGI-------PVSVLTRQECIERIPWIA 759
Query 1070 PECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PEC+++ K A+D WSFG TL+E+ C + + P T++
Sbjct 760 PECVEDSKNLSVAADKWSFGTTLWEI---CYNGEIPLKD-----------KTLIEKERFY 805
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
E R P E+ LM C + + RP F ++ + + E Q P + S
Sbjct 806 ESRCRPVTPSC--KELADLMTRCMNYDPNQRPFFRAIMRDINKLEE----QNPDIVS 856
>sp|Q75R65|JAK2_CHICK Tyrosine-protein kinase JAK2 OS=Gallus gallus
OX=9031 GN=JAK2 PE=2 SV=1
Length=1129
Score = 1172 bits (3031), Expect = 0.0, Method: Composition-based stats.
Identities = 441/1200 (37%), Positives = 637/1200 (53%), Gaps = 130/1200 (11%)
Query 15 VGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLF 74
+G+ + P L+V L+++ G ++ F AEE+CI GI P N+F
Sbjct 24 LGNTSAPKQTEPLLQVYLYYSPGKTGGDYLQFPAGEYVAEEICIVACKACGIMPVYHNMF 83
Query 75 ALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASS 134
AL +VW PPNHI + L L +RIRFYF +W+ Y G+E+
Sbjct 84 ALMSETERVWYPPNHIFHVDEATRLKLLYRIRFYFPHWYCNGTSRACRYGI-IRGSES-- 140
Query 135 DQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHL 194
+LD YLF Q + +F++ + H + E LGMA L + +
Sbjct 141 -------PVLDDLVMSYLFAQWRKDFLDGWIQM------PVTHETQEECLGMAVLDMMRV 187
Query 195 ALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQM 254
A V S+K +P+ R I+++ LTR R+R FR+F++ F + + +
Sbjct 188 AKEKDQTPLAVYNSVSYKMFLPKCVRAKIQEYHILTRKRIRYRFRKFIQQFGQCKATARN 247
Query 255 VMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTH 314
+ +KYL LE L F +E V +PG + +
Sbjct 248 LKLKYLINLETLQSAFYSEVFEVK-----------------------EPGGDPSGEESFA 284
Query 315 EVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLW 374
+++TG GGIQ S G+ ++
Sbjct 285 TIVITGNGGIQC---------------SRGKLKNCETLAEQD-----------------L 312
Query 375 AYFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFR 425
+CDF DI V +K+ V+IH+QD+K LE S ALSFVSL+DGY+R
Sbjct 313 QTYCDFPDIIDVSIKQASQEGSSERRIVTIHKQDSKNLEAEFQSLREALSFVSLIDGYYR 372
Query 426 LTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYR 482
LTAD+ HYLC EVAPP ++ +I+ HGP+ F KL+ + G Y++ S +
Sbjct 373 LTADAHHYLCKEVAPPSVLENIQSNCHGPIFMDFAINKLKKAGNQTGFYVLRCSPKDFKK 432
Query 483 LILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGD 542
LT A + + + K ++G + L G RSF ++++L Q +R+
Sbjct 433 YFLTFAIERENATDYKHCLITK----NENGEYNLSGTKRSFGNLKDLLTCYQTETVRSDS 488
Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTL-------NLSQLSFHRVDQKEITQLSHL 595
F +CC P+P + SNL++ R S N+SQ+ FH++ +++ L
Sbjct 489 IIFQFIKCCPPKPKDKSNLLVFRSNSVSDVPSSPTLQRHNVSQMVFHKIRNEDLIFEESL 548
Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655
GQGT T +++G + G + V+LKVLD H + + +F
Sbjct 549 GQGTFTKIFKGIRKEVGDYGQLH-----------------QTEVLLKVLDKVHRNYSESF 591
Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715
+E AS+MSQ+S+ HL +GVCV G ENI+V EYV+ G LD +L++ + + + WK+ VA
Sbjct 592 FEAASMMSQLSYKHLVLNYGVCVCGEENILVQEYVKFGSLDTYLKKNKNVINILWKLEVA 651
Query 716 QQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+QLA A+ +LE+K LVHGNVC +NILL G PFIKLSDPG+ + L R+ +E
Sbjct 652 KQLALAMHFLEDKGLVHGNVCAKNILLIREEDRKSGNLPFIKLSDPGISITVLPRDILLE 711
Query 775 RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834
RIPW+ PEC+ LS A DKW FG TL EIC G+ PL + S K FY+ +H+LP
Sbjct 712 RIPWVPPECI-ENPRQLSLATDKWSFGTTLWEICSGGDKPLSALDSSRKLQFYEDRHQLP 770
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP--------- 885
P+ +LA L + C+ YEP RPSFR I+RDL L + + +
Sbjct 771 APNWTELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNIRTGALGFS 830
Query 886 ----ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L +H
Sbjct 831 GAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTEEHL 889
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQ 999
+++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H + +
Sbjct 890 RDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERLDHKK 949
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
LLL+A QIC+GM YL + Y+HRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V+E
Sbjct 950 LLLYASQICKGMEYLGTKRYVHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKE 1009
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQGQ 1118
G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG QGQ
Sbjct 1010 PGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQ 1069
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
M V L ELL+ RLPRPD CP E+Y +MK CW + RPTF +L + + + G
Sbjct 1070 MIVFHLIELLKNNGRLPRPDGCPDEIYAIMKECWNNNVAQRPTFRDLAQRVDQIRDNMGG 1129
>sp|Q09178|JAK1_CYPCA Tyrosine-protein kinase JAK1 OS=Cyprinus
carpio OX=7962 GN=jak1 PE=2 SV=1
Length=1156
Score = 1164 bits (3011), Expect = 0.0, Method: Composition-based stats.
Identities = 511/1171 (44%), Positives = 697/1171 (60%), Gaps = 58/1171 (5%)
Query 22 MAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCF-NLFALFDAQ 80
+ M GL++ + + + + TAE++C+ + + C NLFAL +
Sbjct 28 LTVMKGLEIHFYLPDTHQ----LEYFKDCHTAEDLCVEGCQEDATSHLCADNLFALSEES 83
Query 81 AQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCG--PPGTEASSDQTA 138
+W PNH +I + S+ L++R+RFYF NWH E V+R + S +
Sbjct 84 QDLWYAPNHAFKITEETSIKLHYRMRFYFTNWHAPVRTESPVWRHSLFKHKGVSVSPKGP 143
Query 139 QGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRH 198
+G LLD AS EYLF QG+++F+ +A + E E H +NE LGMA L + H A +
Sbjct 144 EGTPLLDAASLEYLFAQGQYDFLRGLAPVRAPQNEAEKHEIENECLGMAVLAITHHAKSN 203
Query 199 GIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQ-----PGRLSQQ 253
+PL V +TS+K IP S R I+Q + NVF+ FL +F ++
Sbjct 204 DLPLSGVGAETSYKRFIPDSLNRTIKQRNFSHVYVYNNVFKNFLNEFNSKTIQDSNITLY 263
Query 254 MVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPT 313
+ VKYL+TLE L G E + L++ +++G P A T P + G
Sbjct 264 DLKVKYLSTLETLTQGLGRETIEPKILKVSGESDGSP--------ALTLPSGDDGLG--- 312
Query 314 HEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPL 373
+EV V+GT GI W S +N KA K + + R+ +
Sbjct 313 YEVQVSGTTGISWRRKPVPNILIVKDKTKSKKN----------KADKQSKKEMTK-RKTV 361
Query 374 WAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHY 433
F DF +ITH+V+KE C +I+ QDNK +EL L R AALSF +LVDGYFRLT D+ HY
Sbjct 362 MTIFSDFFEITHIVIKESCATIYSQDNKTMELDLFYRDAALSFAALVDGYFRLTVDAHHY 421
Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILTV-AQ 489
LC EVAP +V ++ +G HGP+ + KLR E +G Y++ WS + +I+TV
Sbjct 422 LCTEVAPSSVVQNLENGCHGPICTEYAIHKLRQEGNEEGTYVLRWSCTDYNYIIMTVVCI 481
Query 490 RSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRR 549
+ + + F IE + L G P+++EL LQG LR + F
Sbjct 482 EMDLCESRPVPQYKNFQIETSPQGYRLYGTDTFRPTLKELLEHLQGQNLRTENLRFQPVL 541
Query 550 CCLPQPGETSNLIIMRGARA--SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
L QP + SNL++M R S R +SQLSFHR+ ++EI Q HLG+GTRTN+Y G
Sbjct 542 VGLGQPRKISNLLVMTRDREPDSQRQPQVSQLSFHRILKEEIVQGEHLGRGTRTNIYSGV 601
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667
L+++ D + G QE++V+LKVL H DI+LAF+ETAS+M Q+SH
Sbjct 602 LKLKSEDDDDMG------------GYSQEVKVILKVLGSGHRDISLAFFETASMMRQISH 649
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
H+A ++GVCVR ENIMV E+V++GPLD+++RR+ + AWK VA+QLA ALSYLE+
Sbjct 650 KHIALLYGVCVRHQENIMVEEFVQYGPLDLFMRRQSIPLSTAWKFQVAKQLAGALSYLED 709
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGG 787
K LVHGNVC +NIL+AR GL PFIKLSDPG+ + LSREE V+R+PW+APEC+
Sbjct 710 KKLVHGNVCSKNILVARDGLDGEGGPFIKLSDPGIPITVLSREECVDRLPWIAPECVQDT 769
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ 847
AN LS A DKWGFG TL EIC++GE PL+ + +EKE FY Q +L P C +LA L +
Sbjct 770 AN-LSIAADKWGFGTTLWEICYNGEIPLKDKKLTEKERFYAAQCQLASPDCEELAKLMTH 828
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
C+TY+P QR FR I+ + + DPTVF KR+LKKIRDLGEGH
Sbjct 829 CMTYDPRQRLFFRAIV---RDIDMVEKQNPSIQPVPMLEVDPTVFEKRFLKKIRDLGEGH 885
Query 908 FGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
FGKV L YDP D TGE+VAVK+LK + + S +EI ILR LYHE+I+KYKG
Sbjct 886 FGKVELCRYDPRGDRTGELVAVKSLKPENREEQSSNLWREIHILRELYHENIVKYKGIWH 945
Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
++G +S++L+ME++P GSL++YLPR+ I L LL +A QIC+GM L +++YIHRDLA
Sbjct 946 EEGGRSIKLIMEFLPAGSLKEYLPRNKAHIDLKTLLNYAVQICQGMDLLASRNYIHRDLA 1005
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
ARNVL++N+ VKIGDFGL K++ + YY V++D DSPVFWYAPECL KFY ASDVW
Sbjct 1006 ARNVLVENENTVKIGDFGLTKSIKDNEGYYTVKDDLDSPVFWYAPECLIHCKFYRASDVW 1065
Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
SFGVT+YELLT+CD S SP + FL +IG GQMTV RL ++LE G+RLP+PD C +Y
Sbjct 1066 SFGVTMYELLTYCDISCSPMSVFLTMIGPTHGQMTVTRLVKVLEEGKRLPKPDGCSDRLY 1125
Query 1146 HLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
LM+ CWE R F+ LI + + +
Sbjct 1126 CLMRRCWEATPEKRIDFKGLIANFQQMIDNQ 1156
Score = 126 bits (316), Expect = 6e-28, Method: Composition-based stats.
Identities = 63/266 (24%), Positives = 111/266 (42%), Gaps = 38/266 (14%)
Query 929 VKALKADCGPQHRS---GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
VK + G HR + + ++R + H+HI G C E +V E+V G
Sbjct 619 VKVILKVLGSGHRDISLAFFETASMMRQISHKHIALLYGVCVRHQEN--IMVEEFVQYGP 676
Query 986 LRDYLPRHSIGLAQLLLF--AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL------- 1036
L ++ R SI L+ F A+Q+ ++YL + +H ++ ++N+L+ D L
Sbjct 677 LDLFMRRQSIPLSTAWKFQVAKQLAGALSYLEDKKLVHGNVCSKNILVARDGLDGEGGPF 736
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFYYASDVWSFGVTLYELL 1095
+K+ D G+ RE+ + W APEC+++ A+D W FG TL+E+
Sbjct 737 IKLSDPGI-------PITVLSREECVDRLPWIAPECVQDTANLSIAADKWGFGTTLWEI- 788
Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155
C + + P K +L + +L C E+ LM +C +
Sbjct 789 --CYNGEIP-LKDKKLTEKERFYAAQCQLAS-----------PDC-EELAKLMTHCMTYD 833
Query 1156 ASFRPTFENLIPILKTVHEKYQGQAP 1181
R F ++ + V ++ P
Sbjct 834 PRQRLFFRAIVRDIDMVEKQNPSIQP 859
>sp|Q5RB23|JAK2_PONAB Tyrosine-protein kinase JAK2 OS=Pongo abelii
OX=9601 GN=JAK2 PE=2 SV=1
Length=1132
Score = 1147 bits (2968), Expect = 0.0, Method: Composition-based stats.
Identities = 435/1202 (36%), Positives = 636/1202 (53%), Gaps = 132/1202 (11%)
Query 15 VGDGAQPMAAMGGLKVLLHWAGPGGGE-PWVTFSESSLTAEEVCIHIAHKVGITPPCFNL 73
+ A M + + ++ + G E ++TF AEE+CI + GITP N+
Sbjct 25 ISGNANSMKQIDPVLLVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNM 84
Query 74 FALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEAS 133
FAL ++W PPNH+ I + +RIRFYF W+ YR G
Sbjct 85 FALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPRWYCSGSNRA--YRHGISRG--- 139
Query 134 SDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCH 193
LLD YLF Q +H+FV+ + H + E LGMA L +
Sbjct 140 -----AEAPLLDDFVMSYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLDMMR 188
Query 194 LALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQ 253
+A + + S+K +P+ R I+ + LTR R+R FRRF++ F + + +
Sbjct 189 IAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATAR 248
Query 254 MVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPT 313
+ +KYL LE L F TE+ V +PG +
Sbjct 249 NLKLKYLINLETLQSAFYTEKFEVK-----------------------EPGSGPSGEEIF 285
Query 314 HEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPL 373
+++TG GGIQW S G++ ++ ++
Sbjct 286 ATIIITGNGGIQW---------------SRGKHKESETLTEQD----------------- 313
Query 374 WAYFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYF 424
+CDF +I V +K+ V+IH+QD K LE+ L S ALSFVSL+DGY+
Sbjct 314 LQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYY 373
Query 425 RLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPY 481
RLTAD+ HYLC EVAPP ++ +I+ HGP+ F +KL+ + GLY++ S
Sbjct 374 RLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFN 433
Query 482 RLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAG 541
+ LT A + + + K ++ + L G ++F S+++L Q +R+
Sbjct 434 KYFLTFAVERENVIEYKHCLITK----NENEEYNLSGTKKNFSSLKDLLNCYQMETVRSD 489
Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEITQLS 593
+ F +CC P+P + SNL++ R S R +++Q+ FH++ +++
Sbjct 490 NIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNE 549
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LGQGT T +++G R G E V+LKVLD +H + +
Sbjct 550 SLGQGTFTKIFKGVRREVGDYGQLH-----------------ETEVLLKVLDKAHRNYSE 592
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
+F+E AS+MS++SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+
Sbjct 593 SFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLE 652
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREER 772
VA+QLA A+ +LE L+HGNVC +NILL G PFIKLSDPG+ + L ++
Sbjct 653 VAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDIL 712
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832
ERIPW+ PEC+ +L+ A DKW FG TL EIC G+ PL + K FY+ +H+
Sbjct 713 QERIPWVPPECI-ENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQ 771
Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA------ 886
LP P +LA L + C+ YEP RPSFR I+RDL L + + +
Sbjct 772 LPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALG 831
Query 887 -------SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L +
Sbjct 832 FSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTEE 890
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGL 997
H +++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I
Sbjct 891 HLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDH 950
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+LL + QIC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V
Sbjct 951 KKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKV 1010
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQ 1116
+E G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG Q
Sbjct 1011 KEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQ 1070
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
GQM V L ELL+ RLPRPD CP E+Y +M CW + RP+F +L + + +
Sbjct 1071 GQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM 1130
Query 1177 QG 1178
G
Sbjct 1131 AG 1132
>sp|O60674|JAK2_HUMAN Tyrosine-protein kinase JAK2 OS=Homo sapiens
OX=9606 GN=JAK2 PE=1 SV=2
Length=1132
Score = 1145 bits (2963), Expect = 0.0, Method: Composition-based stats.
Identities = 435/1202 (36%), Positives = 635/1202 (53%), Gaps = 132/1202 (11%)
Query 15 VGDGAQPMAAMGGLKVLLHWAGPGGGE-PWVTFSESSLTAEEVCIHIAHKVGITPPCFNL 73
+ A M + + + + G E ++TF AEE+CI + GITP N+
Sbjct 25 ISGNANSMKQIDPVLQVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNM 84
Query 74 FALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEAS 133
FAL ++W PPNH+ I + +RIRFYF W+ YR G
Sbjct 85 FALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPRWYCSGSNRA--YRHGISRG--- 139
Query 134 SDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCH 193
LLD YLF Q +H+FV+ + H + E LGMA L +
Sbjct 140 -----AEAPLLDDFVMSYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLDMMR 188
Query 194 LALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQ 253
+A + + S+K +P+ R I+ + LTR R+R FRRF++ F + + +
Sbjct 189 IAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATAR 248
Query 254 MVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPT 313
+ +KYL LE L F TE+ V +PG +
Sbjct 249 NLKLKYLINLETLQSAFYTEKFEVK-----------------------EPGSGPSGEEIF 285
Query 314 HEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPL 373
+++TG GGIQW S G++ ++ ++
Sbjct 286 ATIIITGNGGIQW---------------SRGKHKESETLTEQD----------------- 313
Query 374 WAYFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYF 424
+CDF +I V +K+ V+IH+QD K LE+ L S ALSFVSL+DGY+
Sbjct 314 LQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYY 373
Query 425 RLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPY 481
RLTAD+ HYLC EVAPP ++ +I+ HGP+ F +KL+ + GLY++ S
Sbjct 374 RLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFN 433
Query 482 RLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAG 541
+ LT A + + + K ++ + L G ++F S+++L Q +R+
Sbjct 434 KYFLTFAVERENVIEYKHCLITK----NENEEYNLSGTKKNFSSLKDLLNCYQMETVRSD 489
Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEITQLS 593
+ F +CC P+P + SNL++ R S R +++Q+ FH++ +++
Sbjct 490 NIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNE 549
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LGQGT T +++G R G E V+LKVLD +H + +
Sbjct 550 SLGQGTFTKIFKGVRREVGDYGQLH-----------------ETEVLLKVLDKAHRNYSE 592
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
+F+E AS+MS++SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+
Sbjct 593 SFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLE 652
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREER 772
VA+QLA A+ +LE L+HGNVC +NILL G PFIKLSDPG+ + L ++
Sbjct 653 VAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDIL 712
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832
ERIPW+ PEC+ +L+ A DKW FG TL EIC G+ PL + K FY+ +H+
Sbjct 713 QERIPWVPPECI-ENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQ 771
Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA------ 886
LP P +LA L + C+ YEP RPSFR I+RDL L + + +
Sbjct 772 LPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALG 831
Query 887 -------SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L +
Sbjct 832 FSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTEE 890
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGL 997
H +++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I
Sbjct 891 HLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDH 950
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+LL + QIC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V
Sbjct 951 IKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKV 1010
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQ 1116
+E G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG Q
Sbjct 1011 KEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQ 1070
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
GQM V L ELL+ RLPRPD CP E+Y +M CW + RP+F +L + + +
Sbjct 1071 GQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM 1130
Query 1177 QG 1178
G
Sbjct 1131 AG 1132
>sp|Q62689|JAK2_RAT Tyrosine-protein kinase JAK2 OS=Rattus norvegicus
OX=10116 GN=Jak2 PE=1 SV=1
Length=1132
Score = 1139 bits (2947), Expect = 0.0, Method: Composition-based stats.
Identities = 434/1196 (36%), Positives = 630/1196 (53%), Gaps = 131/1196 (11%)
Query 16 GDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFA 75
G+ L+V L+ + ++ F AEE+C+ + GITP N+FA
Sbjct 27 GNANSVKQTEPVLQVYLYHSLGQAEGDYLKFPNGEYVAEEICVAASKACGITPVYHNMFA 86
Query 76 LFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSD 135
L ++W PPNH+ I + +RIRFYF +W+ YR G
Sbjct 87 LMSETERIWYPPNHVFHIDESTRHNILYRIRFYFPHWYCSGSNR--TYRYGVSRG----- 139
Query 136 QTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLA 195
LLD YLF Q +H+FV+ + H + E LGMA L + +A
Sbjct 140 ---AEAPLLDDFVMSYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLDMMRIA 190
Query 196 LRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMV 255
V S+K +P+ R I+ + LTR R+R FRRF++ F + + + +
Sbjct 191 KEKDQTPLAVYNSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNL 250
Query 256 MVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHE 315
+KYL LE L F TE+ V E
Sbjct 251 KLKYLINLETLQSAFYTEQFEVKESARGPSGEE-----------------------IFAT 287
Query 316 VLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWA 375
+++TG GGIQW S G++ ++ ++
Sbjct 288 IIITGNGGIQW---------------SRGKHKESETLTEQD-----------------LQ 315
Query 376 YFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRL 426
+CDF DI V +K+ V++H+QD K LE+ L S ALSFVSL+DGY+RL
Sbjct 316 LYCDFPDIIDVSIKQANQECSTESRVVTVHKQDGKVLEIELSSLKEALSFVSLIDGYYRL 375
Query 427 TADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRL 483
TAD+ HYLC EVAPP ++ +I HGP+ F +KL+ + GLY++ S +
Sbjct 376 TADAHHYLCKEVAPPAVLENIHSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKY 435
Query 484 ILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDD 543
LT A + + + K ++G + L G R+F S+++L Q +R+
Sbjct 436 FLTFAVERENVIEYKHCLITK----NENGEYNLSGTKRNFSSLKDLLNCYQMETVRSDSI 491
Query 544 CFSLRRCCLPQPGETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEITQLSHL 595
F +CC P+P + SNL++ R S R N++Q+ FH++ +++ L
Sbjct 492 IFQFTKCCPPKPKDKSNLLVFRTNGVSDVQLSPTLQRHNNVNQMVFHKIRNEDLIFNESL 551
Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655
GQGT T +++G R G E V+LKVLD +H + + +F
Sbjct 552 GQGTFTKIFKGVRREVGDYGQLH-----------------ETEVLLKVLDKAHRNYSESF 594
Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715
+E AS+MSQ+SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+ VA
Sbjct 595 FEAASMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLGVA 654
Query 716 QQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774
+QLA A+ +LE K+L+HGNVC +NILL G PFIKLSDPG+ + L ++ E
Sbjct 655 KQLAWAMHFLEEKSLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQE 714
Query 775 RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834
RIPW+ PEC+ +L+ A DKW FG TL EIC G+ PL + K FY+ +H+LP
Sbjct 715 RIPWVPPECI-ENPKNLTLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDKHQLP 773
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA-------- 886
P +LA L + C+ YEP RP+FR ++RDL L + + +
Sbjct 774 APKWTELANLINTCMDYEPDFRPAFRAVIRDLNSLFTPDYELLTENDMLPNMRIGALGFS 833
Query 887 -----SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L +H
Sbjct 834 GAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTEEHL 892
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQ 999
+++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I +
Sbjct 893 RDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKK 952
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
LL + QIC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V+E
Sbjct 953 LLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKE 1012
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQGQ 1118
G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG QGQ
Sbjct 1013 PGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDKQGQ 1072
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
M V L ELL+ RLPRP+ CP E+Y +M CW + RP+F +L + + +
Sbjct 1073 MIVFHLIELLKNNGRLPRPEGCPDEIYVIMTECWNNNVNQRPSFRDLSLRVDQIRD 1128
>sp|O19064|JAK2_PIG Tyrosine-protein kinase JAK2 OS=Sus scrofa
OX=9823 GN=JAK2 PE=2 SV=1
Length=1131
Score = 1138 bits (2944), Expect = 0.0, Method: Composition-based stats.
Identities = 432/1198 (36%), Positives = 634/1198 (53%), Gaps = 132/1198 (11%)
Query 15 VGDGAQPMAAMGG-LKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNL 73
+ A + + L+V L+ + ++ F AEE+C+ + GITP ++
Sbjct 25 IPGNANSVKQIDPVLQVYLYHSLGKAEGDYLKFPAGEYVAEEICVAASKACGITPVYHSM 84
Query 74 FALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEAS 133
FAL + ++W PPNH+ + + +RIRFYF W+ YR G
Sbjct 85 FALMNETERIWYPPNHVFHVDESTRHNVLYRIRFYFPYWYCNGSNR--TYRHGISRG--- 139
Query 134 SDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCH 193
LLD YLF Q +H+F+ + H + E LGMA L +
Sbjct 140 -----AEAPLLDDFVMSYLFAQWRHDFLYGWVKI------PVTHETQEECLGMAVLDMMR 188
Query 194 LALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQ 253
+A ++ S+K +P+ R I+ + LTR R+R FRRF+ F + + +
Sbjct 189 IAKEKDQTPLDIYSSVSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQFSHCKATAR 248
Query 254 MVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPT 313
+ +KYL LE L F TE+ V +PG +
Sbjct 249 NLKLKYLINLETLQSAFYTEQFEVK-----------------------EPGRGPSGEEIF 285
Query 314 HEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPL 373
+++TG GGIQW S G++ ++ ++
Sbjct 286 ATIIITGNGGIQW---------------SRGKHKESETLTEQD----------------- 313
Query 374 WAYFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYF 424
+CDF DI V +K+ V+IH+QD K LE+ L S ALSFVSL+DGY+
Sbjct 314 LQLYCDFPDIIDVSIKQANQEGSNESRIVTIHKQDGKSLEIELSSLREALSFVSLIDGYY 373
Query 425 RLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPY 481
RLTAD+ HYLC EVAPP ++ +I+ HGP+ F +KL+ + GL+++ S
Sbjct 374 RLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKAGNQTGLFVLRCSPKDFN 433
Query 482 RLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAG 541
+ LT A + + + K ++G + L G ++F ++++L Q +R+
Sbjct 434 KYFLTFAVERENVTEYKHCLITK----NENGEYNLSGTRKNFSNLKDLLNCYQMETVRSD 489
Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEITQLS 593
F +CC P+P + SNL++ R S R N++Q+ FH++ +++
Sbjct 490 SIIFQFTKCCPPKPKDKSNLLVFRTNGISDVPTSPTLQRHNNVNQMVFHKIRNEDLIFNE 549
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LGQGT T +++G R G E V+LKVLD +H + +
Sbjct 550 SLGQGTFTKIFKGVRREVGDYGQLH-----------------ETEVLLKVLDKAHRNYSE 592
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
+F+E AS+MSQ+SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+
Sbjct 593 SFFEAASMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLE 652
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREER 772
VA+QLA A+ +LE K L+HGNVC +NILL G PFIKLSDPG+ + L ++
Sbjct 653 VAKQLAWAMHFLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDIL 712
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832
ERIPW+ PEC+ +L+ A DKW FG TL EIC G+ PL + K FY+ +H+
Sbjct 713 QERIPWVPPECI-ENPKNLNLATDKWSFGTTLWEICSGGDKPLNALDSQRKLQFYEDRHQ 771
Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS----- 887
LP P +LA L + C+ YEP RPSFR I+RDL L + + +
Sbjct 772 LPAPKWTELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALG 831
Query 888 --------DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L +
Sbjct 832 FSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTEE 890
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGL 997
H +++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I
Sbjct 891 HLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDH 950
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+LL + QIC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V
Sbjct 951 KKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKV 1010
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQ 1116
+E G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG Q
Sbjct 1011 KEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQ 1070
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
GQM V L ELL+ RLPRPD CP E+Y +M CW + RP+F +L + + +
Sbjct 1071 GQMIVFHLIELLKNNGRLPRPDGCPDEIYIIMTECWNNNVNQRPSFRDLALRVDQIRD 1128
>sp|Q62120|JAK2_MOUSE Tyrosine-protein kinase JAK2 OS=Mus musculus
OX=10090 GN=Jak2 PE=1 SV=3
Length=1132
Score = 1131 bits (2925), Expect = 0.0, Method: Composition-based stats.
Identities = 435/1199 (36%), Positives = 632/1199 (53%), Gaps = 134/1199 (11%)
Query 15 VGDGAQPMAAMGGLK--VLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFN 72
+ A + + + L H G GE ++ F AEE+C+ + GITP N
Sbjct 25 IPGSANSVKQIEPVLQVYLYHSLGQAEGE-YLKFPSGEYVAEEICVAASKACGITPVYHN 83
Query 73 LFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEA 132
+FAL ++W PPNH+ I + +RIRFYF +W+ YR G
Sbjct 84 MFALMSETERIWYPPNHVFHIDESTRHDILYRIRFYFPHWYCSGS--SRTYRYGVSRG-- 139
Query 133 SSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLC 192
LLD YLF Q +H+FV+ + H + E LGMA L +
Sbjct 140 ------AEAPLLDDFVMSYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLDMM 187
Query 193 HLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQ 252
+A V S+K +P+ R I+ + LTR R+R FRRF++ F + +
Sbjct 188 RIAKEKDQTPLAVYNSVSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATA 247
Query 253 QMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPP 312
+ + +KYL LE L F TE+ V E
Sbjct 248 RNLKLKYLINLETLQSAFYTEQFEVKESARGPSGEE-----------------------I 284
Query 313 THEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREP 372
+++TG GGIQW S G++ ++ ++
Sbjct 285 FATIIITGNGGIQW---------------SRGKHKESETLTEQD---------------- 313
Query 373 LWAYFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGY 423
+CDF DI V +K+ V++H+QD K LE+ L S ALSFVSL+DGY
Sbjct 314 -VQLYCDFPDIIDVSIKQANQECSNESRIVTVHKQDGKVLEIELSSLKEALSFVSLIDGY 372
Query 424 FRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHP 480
+RLTAD+ HYLC EVAPP ++ +I HGP+ F +KL+ + GLY++ S
Sbjct 373 YRLTADAHHYLCKEVAPPAVLENIHSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDF 432
Query 481 YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA 540
+ LT A + + + K ++G + L G R+F ++++L Q +R+
Sbjct 433 NKYFLTFAVERENVIEYKHCLITK----NENGEYNLSGTKRNFSNLKDLLNCYQMETVRS 488
Query 541 GDDCFSLRRCCLPQPGETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEITQL 592
F +CC P+P + SNL++ R S R N++Q+ FH++ +++
Sbjct 489 DSIIFQFTKCCPPKPKDKSNLLVFRTNGISDVQISPTLQRHNNVNQMVFHKIRNEDLIFN 548
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
LGQGT T +++G R G + V+LKVLD +H + +
Sbjct 549 ESLGQGTFTKIFKGVRREVGDYGQLH-----------------KTEVLLKVLDKAHRNYS 591
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
+F+E AS+MSQ+SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+
Sbjct 592 ESFFEAASMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKL 651
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREE 771
VA+QLA A+ +LE K+L+HGNVC +NILL G PFIKLSDPG+ + L ++
Sbjct 652 GVAKQLAWAMHFLEEKSLIHGNVCAKNILLIREEDRRTGNPPFIKLSDPGISITVLPKDI 711
Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
ERIPW+ PEC+ +L+ A DKW FG TL EIC G+ PL + K FY+ +H
Sbjct 712 LQERIPWVPPECI-ENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDKH 770
Query 832 RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA----- 886
+LP P +LA L + C+ YEP RP+FR ++RDL L + + +
Sbjct 771 QLPAPKWTELANLINNCMDYEPDFRPAFRAVIRDLNSLFTPDYELLTENDMLPNMRIGAL 830
Query 887 --------SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L
Sbjct 831 GFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTE 889
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IG 996
+H +++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I
Sbjct 890 EHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERID 949
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
+LL + QIC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+
Sbjct 950 HKKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYK 1009
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-A 1115
V+E G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG
Sbjct 1010 VKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDK 1069
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
QGQM V L ELL+ RLPRP+ CP E+Y +M CW S RP+F +L + + +
Sbjct 1070 QGQMIVFHLIELLKSNGRLPRPEGCPDEIYVIMTECWNNNVSQRPSFRDLSLRVDQIRD 1128
>sp|Q62137|JAK3_MOUSE Tyrosine-protein kinase JAK3 OS=Mus musculus
OX=10090 GN=Jak3 PE=1 SV=2
Length=1100
Score = 1036 bits (2679), Expect = 0.0, Method: Composition-based stats.
Identities = 440/1171 (38%), Positives = 591/1171 (50%), Gaps = 147/1171 (13%)
Query 44 VTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYF 103
++FS AE++C+ A GI P +LFAL W PP+HI I + +L +
Sbjct 41 LSFSFGDYLAEDLCVRAAKACGILPVYHSLFALATEDFSCWFPPSHIFCIEDVDTQVLVY 100
Query 104 RIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVND 163
R+RFYF +W G+ +R G S+ +LD E+LF Q + + V+
Sbjct 101 RLRFYFPDWFGLE----TCHRFGLRKDLTSA--------ILDLHVLEHLFAQHRSDLVSG 148
Query 164 VASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHI 223
+ LS +E + E L +A L L +A E+ K S+K C+P S R I
Sbjct 149 RLPV-GLSMKE-----QGEFLSLAVLDLAQMAREQAQRPGELLKTVSYKACLPPSLRDVI 202
Query 224 RQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLL 283
+ + +TR R+R LR + + +M KY+ LERL P TE V L
Sbjct 203 QGQNFVTRRRIRRTVVLALRRVVACQADRYALMAKYILDLERLHPAATTETFRVG----L 258
Query 284 AQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSS 343
A+ EP +R V G GI W ++E
Sbjct 259 PGAQEEPGLLR-----------------------VAGDNGISWSSGDQE----------- 284
Query 344 GRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKE----------HCV 393
L+ FCDF +I V +K+ V
Sbjct 285 -----------------------------LFQTFCDFPEIVDVSIKQAPRVGPAGEHRLV 315
Query 394 SIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHG 453
++ R D LE P ALSFV+LVDGYFRL DS HY C EVAPPRL+ + HG
Sbjct 316 TVTRMDGHILEAEFPGLPEALSFVALVDGYFRLICDSRHYFCKEVAPPRLLEEEAELCHG 375
Query 454 PLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQ 510
P+ F KL+ G Y++ S +LT ++ + +R+ P
Sbjct 376 PITLDFAIHKLKAAGSLPGTYILRRSPQDYDSFLLTACVQTPLGPDYKGCLIRQDP---- 431
Query 511 DGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGA--- 567
GAF L G + S+REL AA LR +L CC P+P E SNLI++R
Sbjct 432 SGAFSLVGLSQPHRSLRELLAACWNSGLRVDGAALNLTSCCAPRPKEKSNLIVVRRGCTP 491
Query 568 ----RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
SP L+QLSFH + + +LG G+ T ++ GR R G+ +
Sbjct 492 APAPGCSPSCCALTQLSFHTIPTDSLEWHENLGHGSFTKIFRGRRREVVDGETHDS---- 547
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
V+LKV+D H + +F E ASLMSQVS+ HL +HGVC+ G
Sbjct 548 --------------EVLLKVMDSRHRNCMESFLEAASLMSQVSYPHLVLLHGVCMAGDS- 592
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
IMV E+V G +D++LR+ V +WK+ V +QLA AL+YLE+K L HGNV R +LLA
Sbjct 593 IMVQEFVYLGAIDMYLRKRGHLVSASWKLQVTKQLAYALNYLEDKGLPHGNVSARKVLLA 652
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
R G +G PFIKLSDPGV LS E +RIPW+APECL A +L DKWGFGAT
Sbjct 653 REG-GDGNPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQE-AQTLCLEADKWGFGAT 710
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
E+ G A + S P++K FY+ Q +LP +LA L +QC+ Y+P +RPSFR IL
Sbjct 711 TWEVFSGGPAHITSLEPAKKLKFYEDQGQLPALKWTELAGLITQCMAYDPGRRPSFRAIL 770
Query 864 RDLTRLQPHNL--------------ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
RDL L + ++ DP +F +R+LK I LG+G+FG
Sbjct 771 RDLNGLITSDYELLSDPTPGIPSPRDELCGGAQLYACQDPAIFEERHLKYISLLGKGNFG 830
Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
V L YDP D TG +VAVK L GP + +++EI IL+ L+ + I+KY+G
Sbjct 831 SVELCRYDPLGDNTGPLVAVKQL-QHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGP 889
Query 970 GEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027
G +SL+LVMEY+P G LRD+L RH + +LLLFA QIC+GM YL A+ +HRDLAAR
Sbjct 890 GRQSLRLVMEYLPSGCLRDFLQRHRARLHTDRLLLFAWQICKGMEYLGARRCVHRDLAAR 949
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
N+L++++ VKI DFGLAK +P G +YY VRE G SP+FWYAPE L + F SDVWSF
Sbjct 950 NILVESEAHVKIADFGLAKLLPLGKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSF 1009
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
GV LYEL T+CD S SP +FL ++G + + RL ELL G RLP P CP EV L
Sbjct 1010 GVVLYELFTYCDKSCSPSAEFLRMMGPEREGPPLCRLLELLAEGRRLPPPPTCPTEVQEL 1069
Query 1148 MKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
M+ CW RP F L P L + G
Sbjct 1070 MQLCWAPSPHDRPAFGTLSPQLDALWRGRPG 1100
>sp|P52333|JAK3_HUMAN Tyrosine-protein kinase JAK3 OS=Homo sapiens
OX=9606 GN=JAK3 PE=1 SV=2
Length=1124
Score = 1036 bits (2679), Expect = 0.0, Method: Composition-based stats.
Identities = 444/1200 (37%), Positives = 612/1200 (51%), Gaps = 146/1200 (12%)
Query 23 AAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQ 82
G L VLL GPG + ++FS AE++C+ A GI P +LFAL
Sbjct 21 TEAGALHVLLPARGPGPPQ-RLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLS 79
Query 83 VWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQ 142
W PP+HI + ++ +L +RIRFYF NW G+ +R G AS+
Sbjct 80 CWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLE----KCHRFGLRKDLASA-------- 127
Query 143 LLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPL 202
+LD E+LF Q + + V+ + LS +E + E L +A L L +A
Sbjct 128 ILDLPVLEHLFAQHRSDLVSGRLPV-GLSLKE-----QGECLSLAVLDLARMAREQAQRP 181
Query 203 EEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLAT 262
E+ K S+K C+P S R I+ S +TR R+R RR LR + + +M KY+
Sbjct 182 GELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMD 241
Query 263 LERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTG 322
LERL P E V + V G G
Sbjct 242 LERLDPAGAAETFHVGLPGA------------------------LGGHDGLGLLRVAGDG 277
Query 323 GIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRD 382
GI W E+EV FCDF +
Sbjct 278 GIAWTQGEQEV----------------------------------------LQPFCDFPE 297
Query 383 ITHVVLKE----------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSH 432
I + +K+ V++ R DN+ LE P ALSFV+LVDGYFRLT DS H
Sbjct 298 IVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQH 357
Query 433 YLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQ 489
+ C EVAPPRL+ + + HGP+ F KL+ G Y++ S +LTV
Sbjct 358 FFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCV 417
Query 490 RSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRR 549
++ + +R+ P G F+L G R S+REL A L +L
Sbjct 418 QNPLGPDYKGCLIRRSPT----GTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTS 473
Query 550 CCLPQPGETSNLIIMRGARASPRT--------LNLSQLSFHRVDQKEITQLSHLGQGTRT 601
CC+P+P E SNLI+++ + P + LSQ++FH++ + +LG G+ T
Sbjct 474 CCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFT 533
Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL 661
+Y G G+ ++ V+LKV+D H + +F E ASL
Sbjct 534 KIYRGCRHEVVDGE------------------ARKTEVLLKVMDAKHKNCMESFLEAASL 575
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA 721
MSQVS+ HL +HGVC+ G MV E+V G +D++LR+ VP +WK+ V +QLA A
Sbjct 576 MSQVSYRHLVLLHGVCMAGDST-MVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYA 634
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781
L+YLE+K L HGNV R +LLAR G A+G+ PFIKLSDPGV LS E +RIPW+AP
Sbjct 635 LNYLEDKGLPHGNVSARKVLLAREG-ADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAP 693
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL 841
ECL A +LS DKWGFGAT+ E+ P+ + P++K FY+ + +LP P +L
Sbjct 694 ECLRE-AQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTEL 752
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL--------------ADVLTVNPDSPAS 887
A L QC+ YEP QRPSFR ++RDL L + +
Sbjct 753 ALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQ 812
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
DPT+F +R+LK I LG+G+FG V L YDP D TG +VAVK L GP + +++E
Sbjct 813 DPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQL-QHSGPDQQRDFQRE 871
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQ 1005
I IL+ L+ + I+KY+G G +SL+LVMEY+P G LRD+L RH + ++LLL++
Sbjct 872 IQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSS 931
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
QIC+GM YL ++ +HRDLAARN+L++++ VKI DFGLAK +P +YY VRE G SP+
Sbjct 932 QICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPI 991
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
FWYAPE L + F SDVWSFGV LYEL T+CD S SP +FL ++G + + RL
Sbjct 992 FWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLL 1051
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
ELLE G+RLP P CP EV+ LMK CW RP+F L P L + +G F+
Sbjct 1052 ELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAFT 1111
Score = 197 bits (500), Expect = 6e-50, Method: Composition-based stats.
Identities = 68/331 (21%), Positives = 111/331 (34%), Gaps = 54/331 (16%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+++ + +S LG+G +V E V +K L
Sbjct 818 EERHLKYISQLGKGNFGSV--------------------ELCRYDPLGDNTGALVAVKQL 857
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEHGPLDVWLRRE 702
S D F ++ + + GV +V EY+ G L +L+R
Sbjct 858 QHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRH 917
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
R + + ++ + Q+ + YL ++ VH ++ RNIL+ + +K++D G+
Sbjct 918 RARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILV-------ESEAHVKIADFGL 970
Query 763 G-LGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD----- 810
L L ++ V R I W APE L S D W FG L E+
Sbjct 971 AKLLPLDKDYYVVREPGQSPIFWYAPESLSDNI--FSRQSDVWSFGVVLYELFTYCDKSC 1028
Query 811 ---GEAPLQSRSPSEKEHFYQR------QHRLP-EPSCP-QLATLTSQCLTYEPTQRPSF 859
E + + RLP P+CP ++ L C P RPSF
Sbjct 1029 SPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSF 1088
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
+ L L + P
Sbjct 1089 SALGPQLDMLWSGSRGCETHAFTAHPEGKHH 1119
>sp|Q63272|JAK3_RAT Tyrosine-protein kinase JAK3 OS=Rattus norvegicus
OX=10116 GN=Jak3 PE=2 SV=2
Length=1100
Score = 1025 bits (2649), Expect = 0.0, Method: Composition-based stats.
Identities = 434/1167 (37%), Positives = 593/1167 (51%), Gaps = 147/1167 (13%)
Query 44 VTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYF 103
++FS AE++C+ A GI P +LFAL W PP+HI I + +L +
Sbjct 41 LSFSFGDYLAEDLCVRAAKACGILPVYHSLFALATEDLSCWFPPSHIFSIEDVDTQVLVY 100
Query 104 RIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVND 163
R+RFYF W G+ +R G S+ +LD E+LF Q + + V+
Sbjct 101 RLRFYFPGWFGLE----TCHRFGLHKDLTSA--------ILDVHVLEHLFAQHRSDLVSG 148
Query 164 VASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHI 223
+ LS ++ + E L +A L L +A + E+ K S+K C+P S R I
Sbjct 149 RLPV-GLSLKD-----QGEFLSLAVLDLAQMARKQAQRPGELLKSVSYKACLPPSLRDLI 202
Query 224 RQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLL 283
+ S +TR R+R + LR + + +M KY+ LERL P TE V L
Sbjct 203 QGQSFVTRRRIRRTVVQALRRVVACQADRYALMAKYILDLERLHPAATTESFLVG----L 258
Query 284 AQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSS 343
A+ EP +R VTG GI W ++E
Sbjct 259 PGAQEEPGCLR-----------------------VTGDNGIAWSSKDQE----------- 284
Query 344 GRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKE----------HCV 393
L+ FCDF +I V +K+ V
Sbjct 285 -----------------------------LFQTFCDFPEIVDVSIKQAPRVGPAGEHRLV 315
Query 394 SIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHG 453
+I R D LE P ALSFV+LVDGYFRL DS H+ C EVAPPRL+ + HG
Sbjct 316 TITRMDGHILEAEFPGLPEALSFVALVDGYFRLICDSRHFFCKEVAPPRLLEEEAELCHG 375
Query 454 PLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQ 510
P+ F KL+ G Y++ S +LT ++ + +R+ P
Sbjct 376 PITLDFAIHKLKAAGSLPGSYILRRSPQDYDSFLLTACVQTPLGPDYKGCLIRQDP---- 431
Query 511 DGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARA- 569
GAF L G + S++EL A L+ +L CC+P+P E SNLI++R R
Sbjct 432 SGAFSLVGLSQLHRSLQELLTACWHSGLQVDGTALNLTSCCVPRPKEKSNLIVVRRGRNP 491
Query 570 ------SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
SP L++LSFH + + +LG G+ T ++ G R G+
Sbjct 492 TPAPGHSPSCCALTKLSFHTIPADSLEWHENLGHGSFTKIFHGHRREVVDGETH------ 545
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
+ V+LKV+D H + +F E ASLMSQVS+ HL +HGVC+ G
Sbjct 546 ------------DTEVLLKVMDSRHQNCMESFLEAASLMSQVSYPHLVLLHGVCMAGDS- 592
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
IMV E+V G +D +LR+ VP +WK+ V +QLA AL+YLE+K L HGNV R +LLA
Sbjct 593 IMVQEFVYLGAIDTYLRKRGHLVPASWKLQVTKQLAYALNYLEDKGLPHGNVSARKVLLA 652
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
R G+ +G PFIKLSDPGV LS E +RIPW+APECL A +L+ DKWGFGAT
Sbjct 653 REGV-DGNPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQE-AGTLNLEADKWGFGAT 710
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
E+ + S P++K FY+ + +LP +L L +QC+ Y+P +RPSFR IL
Sbjct 711 TWEVFSGAPMHITSLEPAKKLKFYEDRGQLPALKWTELEGLIAQCMAYDPGRRPSFRAIL 770
Query 864 RDLTRLQ--------------PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
RDL L P+ ++ DP +F +R+LK I LG+G+FG
Sbjct 771 RDLNGLITSDYELLSDPTPGIPNPRDELCGGAQLYACQDPAIFEERHLKYISLLGKGNFG 830
Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
V L YDP D TG +VAVK L GP+ + +++EI IL+ L+ + I+KY+G
Sbjct 831 SVELCRYDPLGDNTGPLVAVKQL-QHSGPEQQRDFQREIQILKALHCDFIVKYRGVSYGP 889
Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027
G +SL+LVMEY+P G LRD+L RH L +LLLFA QIC+GM YL A+ +HRDLAAR
Sbjct 890 GRQSLRLVMEYLPSGCLRDFLQRHRARLHNDRLLLFAWQICKGMEYLGARRCVHRDLAAR 949
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
N+L++++ VKI DFGLAK +P G +YY VRE G SP+FWYAPE L + F SDVWSF
Sbjct 950 NILVESEAHVKIADFGLAKLLPLGKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSF 1009
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
GV LYEL T+ D S SP T+FL ++G + + L ELL G RLP P CP EV L
Sbjct 1010 GVVLYELFTYSDKSCSPSTEFLRMMGPEREGSPLCHLLELLAEGRRLPPPSTCPTEVQEL 1069
Query 1148 MKNCWETEASFRPTFENLIPILKTVHE 1174
M+ CW RP F+ L P L +
Sbjct 1070 MQLCWSPNPQDRPAFDTLSPQLDALWR 1096
>sp|Q24592|JAK_DROME Tyrosine-protein kinase hopscotch OS=Drosophila
melanogaster OX=7227 GN=hop PE=1 SV=2
Length=1177
Score = 416 bits (1068), Expect = 1e-124, Method: Composition-based stats.
Identities = 242/1221 (20%), Positives = 422/1221 (35%), Gaps = 167/1221 (14%)
Query 16 GDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFA 75
G +Q + G + ++ ++ EE+C + ++GI P L+
Sbjct 35 GTSSQSIHTNDGTIRVFNFTTGE-----FERFHPNMLCEEICNTMCRQLGIAPIAQLLYG 89
Query 76 LFDAQAQ-----------VWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYR 124
+ + W P L L+ FR+RF
Sbjct 90 IREHSTSRRPSPLVRLDLTWCLPGERLNCQ----LVYCFRMRFRVP-------------- 131
Query 125 CGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESL 184
+ ++L+D S ++L+ Q +++ + E K++S
Sbjct 132 -----------ELDSQLELIDGRSHKFLYRQMRYDMRTEQIP------EIRYPEHKDKST 174
Query 185 GMAFLHLCHLALRHGIPLEEVAK-KTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLR 243
G+A + + + + + +K +P S R HS ++R VFR
Sbjct 175 GLAVMDMLIDDQEQSEDQQAMRSIEKLYKLYLPPSL---WRAHSFFVGSKIREVFR---- 227
Query 244 DFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPC---------YIR 294
+ LS + + Y+ + LAP + TE+ C ++ L E +
Sbjct 228 SLKANSLSVERLKWHYVHQVSHLAPTYMTEQF-TCTVQYLPNEEVARGSGPIGTSLAHST 286
Query 295 DSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGK 354
+ + S T+ V + G+G + + G P SL
Sbjct 287 STLASSGSTNTLSTLTTNTNSVALGGSG-----KKAKRRSTSGGIDVYVRVFPHDSLEPG 341
Query 355 KAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAAL 414
A I ++ V + K E+ +
Sbjct 342 LKVARVTSEATLKWILVGAVEGIFMISKINDTSVRLEIVGLP----KGYEMQFQTEKEMK 397
Query 415 SFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLY 471
SF+S + Y RL++ LCH P L HGP+ + KL G Y
Sbjct 398 SFISYLGIYIRLSSKWMQDLCHSYRTPSLEELSSLHCHGPIGGAYSLMKLHENGDKCGSY 457
Query 472 LIHWSTSHPYRLILTV-AQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELG 530
++ + + + + + F I ++D + L S+ + +
Sbjct 458 IVRECDREYNIYYIDINTKIMAKKTDQERCKTETFRIVRKDSQWKL-----SYNNGEHVL 512
Query 531 AALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASP--RTLNLSQLSFHRVDQKE 588
+L D R + + L+++ L LS+ R + +
Sbjct 513 NSLHEVAHIIQADSPDRYRIPASKYDKPPLLLLLLPKNLKAKKTDLQLSEAELQRRNPQI 572
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+ L + + ++G M + +++ V +K+L
Sbjct 573 FNPRTDL-----------QWYPDSISLSDDGMMFTMRGDWIQQSPVKDVSVTMKMLKSDG 621
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ + F+ A S + ++G+ MV EY +GPL+ +L +V +
Sbjct 622 N--FMEFFRLAQTWSLIQSPQFLKLYGL-TLADPYTMVMEYSRYGPLNKFLH-SMPNVTL 677
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ + L + YLE+ ++H + N+ + + K+SDPG
Sbjct 678 HCLLDLMHGLVRGMHYLEDNKIIHNYIRCSNLYVTKYD-PNSYVLDAKISDPG-----YP 731
Query 769 REERVERIPWLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
R R PW+ + A W F T+ EI + L + +
Sbjct 732 RPYRESDSPWIPVKYYRNLQAAKTDQFAQLWAFATTIYEIFSRCKEDLSTLRQEQLLRQK 791
Query 828 QRQ----HRLPEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN- 881
L + CP + + + T+R S I L ++ L + +
Sbjct 792 NLDGNILKMLDQDICPAPIFETIMDGWSDDETKRFSHHDIFSRLNTIKAEILPNYMPPPE 851
Query 882 -------------------------PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916
T + +G GH+G V
Sbjct 852 IATNGTGDETVIDRSDIPFLPFPRSNMLMVIPLTSECRVIYNMENMIGRGHYGTVYKGHL 911
Query 917 DPTNDGT-GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
+ + E VA+K L Q + + +EI I+RTL H +I+K+K EKS
Sbjct 912 EFNDKDQPREQVAIKMLN---TMQVSTDFHREIGIMRTLSHPNIVKFKYW----AEKSHC 964
Query 976 LVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033
++MEY+ GS YL ++ +L+ FA I GM YL IHRDLAARN+L+D+
Sbjct 965 IIMEYLQSGSFDIYLRFTAPNLNNPRLVSFALDIANGMKYLSDMGLIHRDLAARNILVDH 1024
Query 1034 DRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
+ VKI DFGLA YY + D P+ WY+PE + +F SDVWS+GVT
Sbjct 1025 NGDGDCVKISDFGLA-QFANSDGYYYAKSKRDIPIRWYSPEAISTCRFSSYSDVWSYGVT 1083
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
L+E+ + + P Q + L+ GERL RP CP +Y LM+
Sbjct 1084 LFEMFSRGEEPNLVPI-----------QTSQEDFLNRLQSGERLNRPASCPDFIYDLMQL 1132
Query 1151 CWETEASFRPTFENLIPILKT 1171
CW RP+F ++ I+
Sbjct 1133 CWHATPRSRPSFATIVDIITR 1153
Score = 214 bits (545), Expect = 3e-55, Method: Composition-based stats.
Identities = 70/309 (23%), Positives = 119/309 (39%), Gaps = 40/309 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ +G+G VY+G L P E +V +K+L+
Sbjct 894 MENMIGRGHYGTVYKGHLEFNDKDQPRE-------------------QVAIKMLN--TMQ 932
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
++ F+ +M +SH ++ ++ EY++ G D++LR ++
Sbjct 933 VSTDFHREIGIMRTLSHPNIVKFK-YWAEKSH-CIIMEYLQSGSFDIYLRFTAPNLNNPR 990
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ A +A+ + YL + L+H ++ RNIL+ G + +K+SD G+ A S
Sbjct 991 LVSFALDIANGMKYLSDMGLIHRDLAARNILVDHNGDGD----CVKISDFGLAQFANSDG 1046
Query 771 ERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ I W +PE + S+ D W +G TL E+ GE P + +E
Sbjct 1047 YYYAKSKRDIPIRWYSPEAISTC--RFSSYSDVWSYGVTLFEMFSRGEEPNLVPIQTSQE 1104
Query 825 HFYQR---QHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
F R RL P + L C P RPSF TI+ +TR +
Sbjct 1105 DFLNRLQSGERLNRPASCPDFIYDLMQLCWHATPRSRPSFATIVDIITREVATKVTHPTD 1164
Query 880 VNPDSPASD 888
+ P
Sbjct 1165 GHQSPPNQP 1173
Score = 89.7 bits (221), Expect = 1e-16, Method: Composition-based stats.
Identities = 50/260 (19%), Positives = 92/260 (35%), Gaps = 41/260 (16%)
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
V +K LK+D + + + +K G +VMEY G L
Sbjct 612 VTMKMLKSDGNFM---EFFRLAQTWSLIQSPQFLKLYGLTL---ADPYTMVMEYSRYGPL 665
Query 987 RDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND------RLVKI 1039
+L ++ L LL + GM YL IH + N+ + KI
Sbjct 666 NKFLHSMPNVTLHCLLDLMHGLVRGMHYLEDNKIIHNYIRCSNLYVTKYDPNSYVLDAKI 725
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASD----VWSFGVTLYELL 1095
D G + YR + PV +Y +D +W+F T+YE+
Sbjct 726 SDPGYPR-------PYRESDSPWIPVKYY------RNLQAAKTDQFAQLWAFATTIYEIF 772
Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155
+ C S + L + + + ++L++ D CP ++ + + W +
Sbjct 773 SRCKEDLSTLRQEQLL----RQKNLDGNILKMLDQ-------DICPAPIFETIMDGWSDD 821
Query 1156 ASFRPTFENLIPILKTVHEK 1175
+ R + ++ L T+ +
Sbjct 822 ETKRFSHHDIFSRLNTIKAE 841
>sp|P42688|SRK2_SPOLA Tyrosine-protein kinase SRK2 (Fragment)
OS=Spongilla lacustris OX=6055 GN=SRK2 PE=2 SV=1
Length=362
Score = 323 bits (827), Expect = 3e-99, Method: Composition-based stats.
Identities = 90/402 (22%), Positives = 149/402 (37%), Gaps = 67/402 (17%)
Query 470 LYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVREL 529
+L+ S S P L++ Q D ++ R+RK D F ++++L
Sbjct 1 TFLVRESESKPGDYSLSI----QDGDNVKHYRIRKL-----DEGGFFITRRAVFNTLKDL 51
Query 530 GAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEI 589
Q + C +LR+ C P +L + + + I
Sbjct 52 VQYYQNE---SDGLCVNLRQPCRPLERPQIDL-------------SHKTKDMWEISRDSI 95
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
T + LG G VY+G V +K L
Sbjct 96 TLIRKLGAGQFGEVYQGLW-------------------------NNSTPVAVKTLKAGTM 130
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
A AF A +M ++ H L ++ VC +G ++TE + G L +L+ E G + +
Sbjct 131 QPA-AFLAEAQIMKKLRHPKLIQLYAVCTQGEPVYIITELMSKGSLLDYLQGEAGALKLP 189
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+ +A Q+A+ ++YLE N +H ++ RNIL+ G + K++D G+ +S
Sbjct 190 QLIDMAAQVAAGMAYLELHNYIHRDLAARNILV-------GDNNICKVADFGLARLIVSD 242
Query 770 EERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ I W APE N S D W FG + E+ G P S +E
Sbjct 243 DYNATEGAKFPIKWTAPEAAL--FNRFSIKSDVWSFGILITELVTYGRIPYPGMSNAEVL 300
Query 825 HFYQRQHRLPEPSCPQ--LATLTSQCLTYEPTQRPSFRTILR 864
+ +R+P P L + C P RP+F +
Sbjct 301 QNLDKGYRMPCPVTTPESLYQIMLDCWKRNPADRPTFEALQW 342
Score = 275 bits (703), Expect = 9e-82, Method: Composition-based stats.
Identities = 99/324 (31%), Positives = 152/324 (47%), Gaps = 27/324 (8%)
Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910
+ Q + + QP + ++ D + + IR LG G FG+
Sbjct 49 KDLVQYYQNESDGLCVNLRQPCRPLERPQIDLSHKTKDMWEISRDSITLIRKLGAGQFGE 108
Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970
V + N+ T VAVK LKA G + + E I++ L H +I+ C
Sbjct 109 VYQGLW---NNST--PVAVKTLKA--GTMQPAAFLAEAQIMKKLRHPKLIQLYAVCTQG- 160
Query 971 EKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARN 1028
+ + ++ E + GSL DYL + + L QL+ A Q+ GMAYL +YIHRDLAARN
Sbjct 161 -EPVYIITELMSKGSLLDYLQGEAGALKLPQLIDMAAQVAAGMAYLELHNYIHRDLAARN 219
Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
+L+ ++ + K+ DFGLA+ + Y E P+ W APE +F SDVWSFG
Sbjct 220 ILVGDNNICKVADFGLARLIVSDD--YNATEGAKFPIKWTAPEAALFNRFSIKSDVWSFG 277
Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148
+ + EL+T+ I M+ + + L++G R+P P P +Y +M
Sbjct 278 ILITELVTYGR--------------IPYPGMSNAEVLQNLDKGYRMPCPVTTPESLYQIM 323
Query 1149 KNCWETEASFRPTFENLIPILKTV 1172
+CW+ + RPTFE L L+
Sbjct 324 LDCWKRNPADRPTFEALQWRLEDF 347
>sp|P42690|SRK4_SPOLA Tyrosine-protein kinase isoform SRK4 OS=Spongilla
lacustris OX=6055 GN=SRK1 PE=2 SV=1
Length=506
Score = 323 bits (829), Expect = 1e-97, Method: Composition-based stats.
Identities = 101/430 (23%), Positives = 167/430 (39%), Gaps = 73/430 (17%)
Query 448 RDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
+ G + + +L G +LI S + P L+V R+R
Sbjct 120 EEWFFGQVKRVDAEKQLMMPFNNLGSFLIRDSDTTPGDFSLSVRDID---------RVRH 170
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ I++ + +F S++EL A A C +L+ C+
Sbjct 171 YRIKKLENGTYFVTRRLTFQSIQELVAYYTQQ---ADGLCVNLKGPCM------------ 215
Query 565 RGARASPRTLNLSQLSF--HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
P+T LS+ + +++K+I L LG G V+EG S
Sbjct 216 --VMEKPQTAGLSKQANEEWEIEKKQIKLLRGLGAGQFGEVWEGLWNGTTS--------- 264
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
V +K L P I F E AS+M Q+ H L ++ VC +
Sbjct 265 ----------------VAVKTLKPGTMSI-EEFLEEASIMKQLRHPKLIQLYAVCTKEEP 307
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+VTE ++HG L +LR + + + + + Q+AS +SYLE +N +H ++ RNIL+
Sbjct 308 IYIVTELMKHGSLLEYLRGDGRSLKLPDLVDMCSQVASGMSYLEQQNYIHRDLAARNILV 367
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDK 797
G K++D G+ + I W APE + + D
Sbjct 368 -------GEHKICKVADFGLARVIDEEIYEAKLGAKFPIKWTAPEAAM--YSRFTIKSDV 418
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQ 855
W FG L E+ G P + ++ Q+ +R+P P CP +L + C +P
Sbjct 419 WSFGIVLYEVITYGRFPYPGMTNAQVLEQIQQSYRMPRPMGCPEKLYAIMMDCWREDPAS 478
Query 856 RPSFRTILRD 865
RP+F T+
Sbjct 479 RPTFETLSWQ 488
Score = 285 bits (729), Expect = 1e-83, Method: Composition-based stats.
Identities = 99/305 (32%), Positives = 151/305 (50%), Gaps = 27/305 (9%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+ T A++ K+ +K +R LG G FG+V ++ T VAV
Sbjct 213 PCMVMEKPQTAGLSKQANEEWEIEKKQIKLLRGLGAGQFGEVWEGLWNGT-----TSVAV 267
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K LK G + +E I++ L H +I+ C E+ + +V E + GSL +Y
Sbjct 268 KTLKP--GTMSIEEFLEEASIMKQLRHPKLIQLYAVCTK--EEPIYIVTELMKHGSLLEY 323
Query 990 LPR--HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
L S+ L L+ Q+ GM+YL Q+YIHRDLAARN+L+ ++ K+ DFGLA+
Sbjct 324 LRGDGRSLKLPDLVDMCSQVASGMSYLEQQNYIHRDLAARNILVGEHKICKVADFGLARV 383
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ E E Y + P+ W APE +F SDVWSFG+ LYE++T+
Sbjct 384 IDE--EIYEAKLGAKFPIKWTAPEAAMYSRFTIKSDVWSFGIVLYEVITYGR-------- 433
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
MT ++ E +++ R+PRP CP ++Y +M +CW + + RPTFE L
Sbjct 434 ------FPYPGMTNAQVLEQIQQSYRMPRPMGCPEKLYAIMMDCWREDPASRPTFETLSW 487
Query 1168 ILKTV 1172
L+
Sbjct 488 QLEEF 492
>sp|Q54I36|PYK3_DICDI Dual specificity protein kinase pyk3 OS=Dictyostelium
discoideum OX=44689 GN=pyk3 PE=1 SV=1
Length=1338
Score = 342 bits (876), Expect = 4e-97, Method: Composition-based stats.
Identities = 120/541 (22%), Positives = 213/541 (39%), Gaps = 69/541 (13%)
Query 665 VSHTHLAFVHGVCVRGPENIMVTE-YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723
+ H +L + G C ++ E + L + R+ + MA + +++ +AS +
Sbjct 814 IQHKNLGLLVGWCGDS----IIFESFKGMNSLHDLIHRDGLKIDMALFIKISKDIASVMG 869
Query 724 YLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPEC 783
L +K++ HGN+ R+I L R + +K+S P + A ++APE
Sbjct 870 LLHSKDVAHGNLTSRSIYLDRFQI-------VKVSFPKL--NATDLNNPAIEPRYMAPEM 920
Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAP--LQSRSPSEKEHFYQRQHRLPEPSCPQL 841
+ +S ++D + + L E S + K + + ++P +
Sbjct 921 TRMEEDQISCSIDVYAYAFVLWEALTSHLPFRKFNDISVAAKVAYENLRPKIPTSCPLII 980
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQ---------------------PHNLADVLTV 880
L ++C P+ RP+F IL+ L+
Sbjct 981 RKLINRCWAPLPSDRPTFNDILKLFDHLEGKLFFSSPGILWSLNNDQEVERELQKKERFN 1040
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH 940
+ + +G G F V L + G VA+K LK +
Sbjct 1041 EITEFLRGKKEIKFDEVAIVEKVGAGSFANVFLGIW------NGYKVAIKILKNESISND 1094
Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL 1000
+ +E+ L +H +++ + G C D + EY+ GSL D L I L L
Sbjct 1095 -EKFIKEVSSLIKSHHPNVVTFMGACIDPP----CIFTEYLQGGSLYDVLHIQKIKLNPL 1149
Query 1001 LLF--AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
+++ + GM +LH+ +HRDL ++N+LLD + +KI DFGLA + + +
Sbjct 1150 MMYKMIHDLSLGMEHLHSIQMLHRDLTSKNILLDEFKNIKIADFGLATTLSDD-----MT 1204
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
G + W +PE K + DV+SFG+ +YE+ T + L G A
Sbjct 1205 LSGITNPRWRSPELTKGLVYNEKVDVYSFGLVVYEIYTGKIPFEG-------LDGTASAA 1257
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
R P CP + L+ CW ++ S RP+F ++ L+T+ K+
Sbjct 1258 KAAFE-------NYRPAIPPDCPVSLRKLITKCWASDPSQRPSFTEILTELETMKSKFIK 1310
Query 1179 Q 1179
Q
Sbjct 1311 Q 1311
Score = 200 bits (508), Expect = 9e-51, Method: Composition-based stats.
Identities = 60/321 (19%), Positives = 116/321 (36%), Gaps = 43/321 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ E+ + +G G+ NV+ G +V +
Sbjct 1050 KEIKFDEVAIVEKVGAGSFANVFLGIW--------------------------NGYKVAI 1083
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
K+L F + S + + H ++ G C+ P + TEY++ G L L
Sbjct 1084 KILKNESISNDEKFIKEVSSLIKSHHPNVVTFMGACIDPP--CIFTEYLQGGSLYDVLHI 1141
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
++ + + L+ + +L + ++H ++ +NILL IK++D G
Sbjct 1142 QKIKLNPLMMYKMIHDLSLGMEHLHSIQMLHRDLTSKNILLDEF-------KNIKIADFG 1194
Query 762 VGLGALSREERVE--RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ W +PE G + +D + FG + EI + G+ P +
Sbjct 1195 LATTLSDDMTLSGITNPRWRSPELTKGLV--YNEKVDVYSFGLVVYEI-YTGKIPFEGLD 1251
Query 820 ---PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
+ K F + +P L L ++C +P+QRPSF IL +L ++ +
Sbjct 1252 GTASAAKAAFENYRPAIPPDCPVSLRKLITKCWASDPSQRPSFTEILTELETMKSKFIKQ 1311
Query 877 VLTVNPDSPASDPTVFHKRYL 897
+ +N D +
Sbjct 1312 LSFLNDLIQNPDDDYNNNLNY 1332
Score = 124 bits (310), Expect = 4e-27, Method: Composition-based stats.
Identities = 52/237 (22%), Positives = 97/237 (41%), Gaps = 34/237 (14%)
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVME-YVPLGSLRDYLPRH--SIGLAQLLLFAQQICE 1009
+ H+++ G C D ++ E + + SL D + R I +A + ++ I
Sbjct 813 MIQHKNLGLLVGWCGDS------IIFESFKGMNSLHDLIHRDGLKIDMALFIKISKDIAS 866
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
M LH++ H +L +R++ LD ++VK+ + P + A
Sbjct 867 VMGLLHSKDVAHGNLTSRSIYLDRFQIVKVS--------FPKLNATDLNNPAIEP-RYMA 917
Query 1070 PEC--LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
PE ++E + + DV+++ L+E LT S P KF ++ A ++
Sbjct 918 PEMTRMEEDQISCSIDVYAYAFVLWEALT----SHLPFRKFNDISVAA----------KV 963
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
R P CP + L+ CW S RPTF +++ + + K +P +
Sbjct 964 AYENLRPKIPTSCPLIIRKLINRCWAPLPSDRPTFNDILKLFDHLEGKLFFSSPGIL 1020
>sp|P42686|SRK1_SPOLA Tyrosine-protein kinase isoform SRK1 OS=Spongilla
lacustris OX=6055 GN=SRK1 PE=2 SV=1
Length=505
Score = 320 bits (821), Expect = 1e-96, Method: Composition-based stats.
Identities = 97/445 (22%), Positives = 162/445 (36%), Gaps = 69/445 (16%)
Query 448 RDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
+ G + + L + G +LI S + P L+V + R+R
Sbjct 120 EEWFLGKIKRVEAEKMLNQSFNQVGSFLIRDSETTPGDFSLSVKDQD---------RVRH 170
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ + + + + +F + EL + + C L CL + ++
Sbjct 171 YRVRRLEDGSLFVTRRSTFQILHELVDHYK---IETDGLCCKLLYPCLQAEKPQTAGLLR 227
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
+ +++ +I L LG G V+EG S
Sbjct 228 QANEE------------WEIEKTQIKLLRRLGAGQFGEVWEGLWNGTTS----------- 264
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
V +K L P + F + AS+M ++ H L ++ VC +
Sbjct 265 --------------VAVKTLKPGTMSV-EEFLQEASIMKRLRHPKLIQLYAVCTKEEPIY 309
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+VTE +++G L +LR E G + + + VA Q+AS +SYLE +N +H ++ RNIL+
Sbjct 310 IVTELMKYGSLLEYLRGEDGVLKIEQLVDVAAQVASGMSYLEQQNYIHRDLAARNILVGE 369
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWG 799
G+ K++D G+ I W APE N + D W
Sbjct 370 HGI-------CKVADFGLARVIDEEIYEAHTGAKFPIKWTAPEAAM--YNRFTIKSDVWS 420
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRP 857
FG L EI G P + E Q+ +R+P P +CP Q + C +P RP
Sbjct 421 FGVVLYEIITYGRFPYPGMTNPEVLEKIQQNYRMPCPANCPKQFHDIMLDCWREDPASRP 480
Query 858 SFRTILRDLTRLQPHNLADVLTVNP 882
+F T+ L
Sbjct 481 TFETLQWQLEEFFNSEGYRDPDAIH 505
Score = 289 bits (739), Expect = 5e-85, Method: Composition-based stats.
Identities = 100/322 (31%), Positives = 147/322 (46%), Gaps = 27/322 (8%)
Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923
T A++ K +K +R LG G FG+V ++ T
Sbjct 207 CCKLLYPCLQAEKPQTAGLLRQANEEWEIEKTQIKLLRRLGAGQFGEVWEGLWNGT---- 262
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
VAVK LK G + QE I++ L H +I+ C E+ + +V E +
Sbjct 263 -TSVAVKTLKP--GTMSVEEFLQEASIMKRLRHPKLIQLYAVCTK--EEPIYIVTELMKY 317
Query 984 GSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
GSL +YL + + QL+ A Q+ GM+YL Q+YIHRDLAARN+L+ + K+ D
Sbjct 318 GSLLEYLRGEDGVLKIEQLVDVAAQVASGMSYLEQQNYIHRDLAARNILVGEHGICKVAD 377
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLA+ + E E Y P+ W APE +F SDVWSFGV LYE++T+
Sbjct 378 FGLARVIDE--EIYEAHTGAKFPIKWTAPEAAMYNRFTIKSDVWSFGVVLYEIITYGR-- 433
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
MT + E +++ R+P P CP + + +M +CW + + RPT
Sbjct 434 ------------FPYPGMTNPEVLEKIQQNYRMPCPANCPKQFHDIMLDCWREDPASRPT 481
Query 1162 FENLIPILKTVHEKYQGQAPSV 1183
FE L L+ + P
Sbjct 482 FETLQWQLEEFFNSEGYRDPDA 503
>sp|P18652|KS6AA_CHICK Ribosomal protein S6 kinase 2 alpha OS=Gallus
gallus OX=9031 GN=RPS6KA PE=2 SV=1
Length=752
Score = 326 bits (835), Expect = 1e-95, Method: Composition-based stats.
Identities = 125/662 (19%), Positives = 215/662 (32%), Gaps = 122/662 (18%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ D + L LGQG+ V+ + D + L +
Sbjct 73 EKADPSQFELLKVLGQGSFGKVFL----------VRKITPPDSNHLY-----------AM 111
Query 642 KVLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
KVL + + +++ V+H + +H + ++ +++ G L L
Sbjct 112 KVLKKATLKVRDRVRTKIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRL 171
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+E K +A +LA L +L + +++ ++ NILL G IKL+D
Sbjct 172 SKEVMFTEEDVKFYLA-ELALGLDHLHSLGIIYRDLKPENILLDEEG-------HIKLTD 223
Query 760 PGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ A+ E++ + ++APE + +S S D W +G + E+ G P
Sbjct 224 FGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS--ADWWSYGVLMFEML-TGSLPF 280
Query 816 QSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQR--------------PSFR 860
Q + E + +P+ + +L P R P +
Sbjct 281 QGKDRKETMTLILKAKLGMPQFLSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYS 340
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK-----------IRDLGEGHF- 908
TI + + V K + F
Sbjct 341 TIDWNKLYRREIKPPFKPAVGQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFV 400
Query 909 ------------------GKVSLYCYDPTNDGTGEMV--AV-------------KALKAD 935
V G +V A+ K +
Sbjct 401 ATGLMEDSKVKPAQPPLHSVVQQLHGKNIQFSDGYVVKEAIGVGSYSVCKRCIHKTTNME 460
Query 936 CGPQHRSGWKQ----EIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
+ K+ EI+IL H +II K +D K + LV E + G L D +
Sbjct 461 YAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDG--KYVYLVTELMRGGELLDKI 518
Query 991 PRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL-LDNDRL---VKIGDFGLA 1045
R + IC+ + YLH+Q +HRDL N+L +D ++I DFG A
Sbjct 519 LRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFA 578
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
K + + + APE LK + D+WS GV LY +L C + P
Sbjct 579 KQLRAENGLLMT---PCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGP 635
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ E I +T + + G D L+ + R T + +
Sbjct 636 SDTPEEI------LTRIGGGKFSVNGGNW---DTISDVAKDLVSKMLHVDPHQRLTAKQV 686
Query 1166 IP 1167
+
Sbjct 687 LQ 688
Score = 152 bits (383), Expect = 2e-36, Method: Composition-based stats.
Identities = 50/286 (17%), Positives = 93/286 (33%), Gaps = 24/286 (8%)
Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SHTH 669
+G E + + + +KV+D S D + E ++ + H +
Sbjct 433 DGYVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSKRDPS----EEIEILLRYGQHPN 488
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729
+ + V G +VTE + G L + R++ V + + YL ++
Sbjct 489 IITLKDVYDDGKYVYLVTELMRGGELLDKILRQKF-FSEREASSVLHTICKTVEYLHSQG 547
Query 730 LVHGNVCGRNIL-LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL----APECL 784
+VH ++ NIL + G E I++ D G + + + APE L
Sbjct 548 VVHRDLKPSNILYVDESGNPES----IRICDFGFAKQLRAENGLLMTPCYTANFVAPEVL 603
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-------HRLPEPS 837
D W G L + S + +E + +
Sbjct 604 K--RQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTI 661
Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
L S+ L +P QR + + +L+ Q +L D
Sbjct 662 SDVAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLPQSQLNYQD 707
>sp|Q9UK32|KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 OS=Homo
sapiens OX=9606 GN=RPS6KA6 PE=1 SV=1
Length=745
Score = 325 bits (834), Expect = 1e-95, Method: Composition-based stats.
Identities = 129/696 (19%), Positives = 230/696 (33%), Gaps = 138/696 (20%)
Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
+ P T ++ + + + D + L LGQG+ V+ R +
Sbjct 53 KEIPITHHVKE-GYEKADPAQFELLKVLGQGSFGKVFLVRKKT----------------- 94
Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIM 685
G D GQ +KVL + + ++ +V+H + +H + +
Sbjct 95 --GPDAGQ--LYAMKVLKKASLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYL 150
Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
+ +++ G + L +E K +A +LA AL +L +V+ ++ NILL +
Sbjct 151 ILDFLRGGDVFTRLSKEVLFTEEDVKFYLA-ELALALDHLHQLGIVYRDLKPENILLDEI 209
Query 746 GLAEGTSPFIKLSDPGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFG 801
G IKL+D G+ ++ +E++ + ++APE + S + D W +G
Sbjct 210 G-------HIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVV--NRRGHSQSADWWSYG 260
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQRPSFR 860
+ E+ G P Q + +E + + +P+ + +L P R
Sbjct 261 VLMFEML-TGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPANRLGSE 319
Query 861 TILRDLTRLQ---------PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG----- 906
+ L D F + K G
Sbjct 320 GVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPEFTAKTPKDSPGLPASA 379
Query 907 -----------------------------------------HFGKVSL-----------Y 914
FG+V
Sbjct 380 NAHQLFKGFSFVATSIAEEYKITPITSANVLPIVQINGNAAQFGEVYELKEDIGVGSYSV 439
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKS 973
C + T AVK + + +EI+IL H +II K +D +
Sbjct 440 CKRCIHATTNMEFAVKIIDKS-----KRDPSEEIEILMRYGQHPNIITLKDVFDDG--RY 492
Query 974 LQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032
+ LV + + G L D L + + I + + YLH Q +HRDL N+L
Sbjct 493 VYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDLKPSNILYM 552
Query 1033 ND----RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
++ ++I DFG AK + + + APE L + + A D+WS G
Sbjct 553 DESASADSIRICDFGFAKQLRGENGLLLT---PCYTANFVAPEVLMQQGYDAACDIWSLG 609
Query 1089 VTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
V Y +L + P E L+ I G+ ++ D
Sbjct 610 VLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNW-----------DNISDGAKD 658
Query 1147 LMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182
L+ + + R T E + LK ++ Q P+
Sbjct 659 LLSHMLHMDPHQRYTAEQI---LKHSWITHRDQLPN 691
Score = 150 bits (379), Expect = 6e-36, Method: Composition-based stats.
Identities = 49/316 (16%), Positives = 92/316 (29%), Gaps = 33/316 (10%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETA 659
VYE E+ + + +K++D S D + E
Sbjct 422 FGEVYE---------LKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPS----EEI 468
Query 660 SLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQL 718
++ + H ++ + V G +VT+ ++ G L + +++ + +
Sbjct 469 EILMRYGQHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKC-FSEREASDILYVI 527
Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPW 778
+ + YL + +VH ++ NIL ++ I++ D G + +
Sbjct 528 SKTVDYLHCQGVVHRDLKPSNIL---YMDESASADSIRICDFGFAKQLRGENGLLLTPCY 584
Query 779 L----APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS--EKEHFYQRQHR 832
APE L A D W G L G P + E+ +
Sbjct 585 TANFVAPEVLMQ--QGYDAACDIWSLGV-LFYTMLAGYTPFANGPNDTPEEILLRIGNGK 641
Query 833 L------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
+ L S L +P QR + IL+ L + D
Sbjct 642 FSLSGGNWDNISDGAKDLLSHMLHMDPHQRYTAEQILKHSWITHRDQLPNDQPKRNDVSH 701
Query 887 SDPTVFHKRYLKKIRD 902
Y
Sbjct 702 VVKGAMVATYSALTHK 717
>sp|Q62662|FRK_RAT Tyrosine-protein kinase FRK OS=Rattus norvegicus
OX=10116 GN=Frk PE=1 SV=3
Length=506
Score = 318 bits (814), Expect = 1e-95, Method: Composition-based stats.
Identities = 101/459 (22%), Positives = 174/459 (38%), Gaps = 74/459 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VA R + + G + + +L + G +LI S S L+V
Sbjct 106 VAEDRSLQA-EPWFFGAIKRADAEKQLLYSENQTGAFLIRESESQKGDFSLSVLDEG--- 161
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
++ + I + D ++F ++ E + C L + CL
Sbjct 162 ------VVKHYRIRRLDEGGFFLTRRKTFSTLNEFVNYYTTT---SDGLCVKLEKPCL-- 210
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ +P L+ + +D+ I L LG G V+EG
Sbjct 211 ----------KIQVPTPFDLSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGLW------ 254
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
V +K L P D F A +M + H L ++
Sbjct 255 -------------------NNTTPVAVKTLKPGSMDPN-DFLREAQIMKSLRHPKLIQLY 294
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHG 733
VC ++TE + HG L +L+ + G + + ++ +A Q+AS ++YLE++N +H
Sbjct 295 AVCTLEDPIYIITELMRHGSLQEYLQNDGGSKIRLTQQVDMAAQVASGMAYLESQNYIHR 354
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLG--------ALSREERVERIPWLAPECLP 785
++ RN+L+ + K++D G+ S+ E + W APE +
Sbjct 355 DLAARNVLVGEHNIY-------KVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIR 407
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLAT 843
N S D W FG L EI G+ P + ++ H + +RLP+P +CP Q +
Sbjct 408 T--NKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIHMLGQNYRLPQPSNCPEQFYS 465
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
+ +C EP QRP+F T+ L + + T N
Sbjct 466 IMMECWNVEPKQRPTFETLHWKLEDYFEPDSSYSDTNNF 504
Score = 281 bits (720), Expect = 2e-82, Method: Composition-based stats.
Identities = 99/309 (32%), Positives = 150/309 (49%), Gaps = 27/309 (9%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+ + D + ++ ++ LG G FG+V ++ T VAV
Sbjct 208 PCLKIQVPTPFDLSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNT-----TPVAV 262
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K LK G + + +E I+++L H +I+ C E + ++ E + GSL++Y
Sbjct 263 KTLKP--GSMDPNDFLREAQIMKSLRHPKLIQLYAVCT--LEDPIYIITELMRHGSLQEY 318
Query 990 LPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
L I L Q + A Q+ GMAYL +Q+YIHRDLAARNVL+ + K+ DFGLA+
Sbjct 319 LQNDGGSKIRLTQQVDMAAQVASGMAYLESQNYIHRDLAARNVLVGEHNIYKVADFGLAR 378
Query 1047 AVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + Y + + PV W APE ++ KF SDVWSFG+ LYE++T+
Sbjct 379 VFKVDNEDIYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGK------ 432
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ MT ++ +L + RLP+P CP + Y +M CW E RPTFE L
Sbjct 433 --------MPYSGMTGAQVIHMLGQNYRLPQPSNCPEQFYSIMMECWNVEPKQRPTFETL 484
Query 1166 IPILKTVHE 1174
L+ E
Sbjct 485 HWKLEDYFE 493
>sp|O45539|SRC2_CAEEL Tyrosine protein-kinase src-2 OS=Caenorhabditis
elegans OX=6239 GN=src-2 PE=1 SV=2
Length=507
Score = 318 bits (814), Expect = 1e-95, Method: Composition-based stats.
Identities = 101/437 (23%), Positives = 164/437 (38%), Gaps = 73/437 (17%)
Query 446 SIRDGIHGP---LLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502
+ G + E G +L+ S S + L L+V + D ++ R+
Sbjct 120 ESQPWYFGKMRRIDAEKCLLHTLNEHGAFLVRDSESRQHDLSLSVREN----DSVKHYRI 175
Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562
R+ D R F ++ +L A Q A C +L C
Sbjct 176 RQL-----DHGGYFIARRRPFATLHDLIAHYQRE---ADGLCVNLGAPC----------- 216
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
+P+T + VD++ + + +G G V+EGR V
Sbjct 217 ---AKSEAPQTTTFTYDDQWEVDRRSVRLIRQIGAGQFGEVWEGRWNVN----------- 262
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
+ V +K L D F A +M ++ H L ++ VC R
Sbjct 263 --------------VPVAVKKLKAGTADP-TDFLAEAQIMKKLRHPKLLSLYAVCTRDEP 307
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
++VTE ++ L +L+R M + ++ Q+A+ ++YLE N +H ++ RNIL+
Sbjct 308 ILIVTELMQ-ENLLTFLQRRGRQCQMPQLVEISAQVAAGMAYLEEMNFIHRDLAARNILI 366
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMD 796
S +K++D G+ + E R I W APE N +T D
Sbjct 367 NN-------SLSVKIADFGLARILMKENEYEARTGARFPIKWTAPEAA--NYNRFTTKSD 417
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPT 854
W FG L EI G P + +E +R+P P CP L + QC +P
Sbjct 418 VWSFGILLTEIVTFGRLPYPGMTNAEVLQQVDAGYRMPCPAGCPVTLYDIMQQCWRSDPD 477
Query 855 QRPSFRTILRDLTRLQP 871
+RP+F T+ L L
Sbjct 478 KRPTFETLQWKLEDLFN 494
Score = 273 bits (698), Expect = 3e-79, Method: Composition-based stats.
Identities = 94/321 (29%), Positives = 145/321 (45%), Gaps = 27/321 (8%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915
R L D +R ++ IR +G G FG+V
Sbjct 199 AHYQREADGLCVNLGAPCAKSEAPQTTTFTYDDQWEVDRRSVRLIRQIGAGQFGEVWEGR 258
Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
++ VAVK LKA G + + E I++ L H ++ C ++ +
Sbjct 259 WNV-----NVPVAVKKLKA--GTADPTDFLAEAQIMKKLRHPKLLSLYAVCTR--DEPIL 309
Query 976 LVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033
+V E + +L +L R + QL+ + Q+ GMAYL ++IHRDLAARN+L++N
Sbjct 310 IVTELMQE-NLLTFLQRRGRQCQMPQLVEISAQVAAGMAYLEEMNFIHRDLAARNILINN 368
Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
VKI DFGLA+ + + +E Y R P+ W APE +F SDVWSFG+ L E
Sbjct 369 SLSVKIADFGLARILMKENE-YEARTGARFPIKWTAPEAANYNRFTTKSDVWSFGILLTE 427
Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
++T + MT + + ++ G R+P P CP +Y +M+ CW
Sbjct 428 IVTFGR--------------LPYPGMTNAEVLQQVDAGYRMPCPAGCPVTLYDIMQQCWR 473
Query 1154 TEASFRPTFENLIPILKTVHE 1174
++ RPTFE L L+ +
Sbjct 474 SDPDKRPTFETLQWKLEDLFN 494
>sp|P00528|SRC64_DROME Tyrosine-protein kinase Src64B OS=Drosophila
melanogaster OX=7227 GN=Src64B PE=1 SV=3
Length=552
Score = 319 bits (818), Expect = 1e-95, Method: Composition-based stats.
Identities = 97/435 (22%), Positives = 159/435 (37%), Gaps = 70/435 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502
+ D +L L E+ G +L+ S +P L+V + +
Sbjct 158 NSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDG----RGYHV 213
Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL-PQPGETSNL 561
+ + I+ D ++FPS++ L A L C L R C PQP
Sbjct 214 KHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNAL---GLCHILSRPCPKPQPQMWDLG 270
Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
+R + + + EI L LG+G V+ G+ R
Sbjct 271 PELR--------------DKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNS---------- 306
Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
+ V +K L A AF + A++M + H L ++ VC +
Sbjct 307 ---------------IDVAVKTLREGTMSTA-AFLQEAAIMKKFRHNRLVALYAVCSQEE 350
Query 682 ENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNI 740
+V EY+ G L +LR G + + +A Q+AS + YLE+K L+H ++ RN+
Sbjct 351 PIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNV 410
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAM 795
L+ +A K+ D G+ E + + W APE + G S
Sbjct 411 LIGENNVA-------KICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYG--KFSIKS 461
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP----EPSCPQLATLTSQCLTY 851
D W +G L+E+ G+ P E +R R+P + L QC
Sbjct 462 DVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDA 521
Query 852 EPTQRPSFRTILRDL 866
P +RP+F +
Sbjct 522 VPEKRPTFEFLNHYF 536
Score = 259 bits (663), Expect = 4e-74, Method: Composition-based stats.
Identities = 93/319 (29%), Positives = 143/319 (45%), Gaps = 30/319 (9%)
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918
+ +P + D + ++ +R LG G+FG+V +
Sbjct 246 KNALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRN 305
Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978
+ D VAVK L+ G + + QE I++ H ++ C E+ + +V
Sbjct 306 SID-----VAVKTLRE--GTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQ--EEPIYIVQ 356
Query 979 EYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035
EY+ GSL D+L + L+ A Q+ GM YL ++ IHRDLAARNVL+ +
Sbjct 357 EYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENN 416
Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+ KI DFGLA+ + + Y ++ PV W APE + KF SDVWS+G+ L EL
Sbjct 417 VAKICDFGLARVIADDE--YCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELF 474
Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK--CPCEVYHLMKNCWE 1153
T+ + M + E +ERG R+P+P P +Y L+ CW+
Sbjct 475 TYGQ--------------VPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWD 520
Query 1154 TEASFRPTFENLIPILKTV 1172
RPTFE L ++
Sbjct 521 AVPEKRPTFEFLNHYFESF 539
>sp|Q552C6|ZAK2_DICDI Dual specificity protein kinase zak2 OS=Dictyostelium
discoideum OX=44689 GN=zak2 PE=1 SV=1
Length=635
Score = 320 bits (820), Expect = 8e-95, Method: Composition-based stats.
Identities = 104/600 (17%), Positives = 203/600 (34%), Gaps = 119/600 (20%)
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K+++ ++ ++ ++ + + EY+E
Sbjct 42 VAVKIINKKFFK-----RNETDILEKIRLFNIPRYYSHAEDDNYIYIYMEYIE------- 89
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+++ + + + L LS+L ++H ++ NI+L + G+ +KL
Sbjct 90 -DKKQLRFKESEIISMIADLTETLSFLHKHQILHRDIKPSNIILDKNGV-------LKLI 141
Query 759 DPGVGLGALSREE-----------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
D G + +++ ++APE + + D W G T+LEI
Sbjct 142 DFGSSIIDQQQDDGDNICKESSFAITGTHTYMAPEV--KKLHRSTKKSDVWSLGCTVLEI 199
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
G P + + +P + +CL +P +R +L
Sbjct 200 V--GGNP---------KKIFDGIPIIPNHVSEIMVDFIKRCLIIDPNKRSHMEELLTHRL 248
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG---------------------EG 906
N + ++ + K + +G
Sbjct 249 ISSMVGQNKNRENNIEPKFNNDYLSSKFPERFAPRFEKPKWEIEFNELKFNKDDTVGGDG 308
Query 907 HFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHIIKYKG 964
F V Y+ T VA+K +K G + E+ I+ L H +I+++
Sbjct 309 FFSVVKKGYYNET------EVAIKLIKKAHGENVTVCDTFYHEVLIISNLRHPNIVQFIA 362
Query 965 CCE--DQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQH 1018
C D E + +V E++ G+L ++ I + I +GM Y H Q
Sbjct 363 ACIKFDNKEVNHCIVSEWMSGGNLSQFISNERKILEINPHLRVKILLDIAKGMLYSHRQG 422
Query 1019 YIHRDLAARNVLLD---------------------NDRLVKIGDFGLAKAVPEGHEYYRV 1057
IHRDL + NVLL+ ++ + K+ DFGL+ E +
Sbjct 423 IIHRDLTSNNVLLNFRKKKLLNNNSSNNDEQFYDSDEIIAKVCDFGLSSNQSESKKL--- 479
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
+ + APE L SD++SFG+ ++++ ++
Sbjct 480 ---RGGSIHYMAPENLNGSPINEKSDIYSFGLLVWQMFSYASP------------NTIYS 524
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP-TFENLIPILKTVHEKY 1176
+ + + R P P + L+ CW+ RP F +I LK +++ Y
Sbjct 525 PKEMASMVSDEKLNYRPQIPFNVPLKFKELITQCWDRNPLNRPKDFSEIIDKLKDINQIY 584
Score = 190 bits (483), Expect = 2e-49, Method: Composition-based stats.
Identities = 51/310 (16%), Positives = 109/310 (35%), Gaps = 61/310 (20%)
Query 582 HRVDQKEITQLS---HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
++ E+ G G + V +G E
Sbjct 289 WEIEFNELKFNKDDTVGGDGFFSVVKKG--------------------------YYNETE 322
Query 639 VVLKVLDPSHHDIA---LAFYETASLMSQVSHTHLAFVHGVCVRGPE----NIMVTEYVE 691
V +K++ +H + FY ++S + H ++ C++ + +V+E++
Sbjct 323 VAIKLIKKAHGENVTVCDTFYHEVLIISNLRHPNIVQFIAACIKFDNKEVNHCIVSEWMS 382
Query 692 HGPLDVWLRRERGHVPMA--WKMVVAQQLASALSYLENKNLVHGNVCGRNILLA------ 743
G L ++ ER + + ++ + +A + Y + ++H ++ N+LL
Sbjct 383 GGNLSQFISNERKILEINPHLRVKILLDIAKGMLYSHRQGIIHRDLTSNNVLLNFRKKKL 442
Query 744 --------RLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIPWLAPECLPGGANSLSTA 794
+ K+ D G+ + S++ R I ++APE L G + ++
Sbjct 443 LNNNSSNNDEQFYDSDEIIAKVCDFGLSSNQSESKKLRGGSIHYMAPENLNG--SPINEK 500
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-----QRQHRLPEPSCPQLATLTSQCL 849
D + FG + ++ +P SP E + ++P + L +QC
Sbjct 501 SDIYSFGLLVWQMFSYA-SPNTIYSPKEMASMVSDEKLNYRPQIPFNVPLKFKELITQCW 559
Query 850 TYEPTQRPSF 859
P RP
Sbjct 560 DRNPLNRPKD 569
Score = 155 bits (391), Expect = 8e-38, Method: Composition-based stats.
Identities = 48/246 (20%), Positives = 95/246 (39%), Gaps = 45/246 (18%)
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
+VAVK + + E DIL + +I +Y + + + + MEY+
Sbjct 41 IVAVKIINKKFFK------RNETDILEKIRLFNIPRYY--SHAEDDNYIYIYMEYIEDK- 91
Query 986 LRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+ ++++ + E +++LH +HRD+ N++LD + ++K+ DFG +
Sbjct 92 -----KQLRFKESEIISMIADLTETLSFLHKHQILHRDIKPSNIILDKNGVLKLIDFGSS 146
Query 1046 KAVPEGHEYYRVREDG----DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
+ + + ++ + APE K ++ SDVWS G T+ E++
Sbjct 147 IIDQQQDDGDNICKESSFAITGTHTYMAPEVKKLHRSTKKSDVWSLGCTVLEIVGGN--- 203
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
P K + I I P+ + +K C + + R
Sbjct 204 ---PKKIFDGIPI---------------------IPNHVSEIMVDFIKRCLIIDPNKRSH 239
Query 1162 FENLIP 1167
E L+
Sbjct 240 MEELLT 245
>sp|P42685|FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo sapiens
OX=9606 GN=FRK PE=1 SV=1
Length=505
Score = 314 bits (805), Expect = 2e-94, Method: Composition-based stats.
Identities = 98/441 (22%), Positives = 169/441 (38%), Gaps = 74/441 (17%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VA R + + G + + +L + G +LI S S L+V
Sbjct 105 VAEDRSLQA-EPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLD----- 158
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
++ + I++ D R F ++ E + + C L + CL
Sbjct 159 ----GAVVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHYTKT---SDGLCVKLGKPCL-- 209
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ +P L+ + +D+ I L LG G V+EG
Sbjct 210 ----------KIQVPAPFDLSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGLW------ 253
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
V +K L P D F A +M + H L ++
Sbjct 254 -------------------NNTTPVAVKTLKPGSMDPN-DFLREAQIMKNLRHPKLIQLY 293
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHG 733
VC ++TE + HG L +L+ + G + + ++ +A Q+AS ++YLE++N +H
Sbjct 294 AVCTLEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHR 353
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLG--------ALSREERVERIPWLAPECLP 785
++ RN+L+ + K++D G+ SR E + W APE +
Sbjct 354 DLAARNVLVGEHNIY-------KVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIR 406
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLAT 843
+N S D W FG L EI G+ P + ++ + +RLP+P +CP Q
Sbjct 407 --SNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYN 464
Query 844 LTSQCLTYEPTQRPSFRTILR 864
+ +C EP +RP+F T+
Sbjct 465 IMLECWNAEPKERPTFETLRW 485
Score = 282 bits (721), Expect = 2e-82, Method: Composition-based stats.
Identities = 99/309 (32%), Positives = 151/309 (49%), Gaps = 27/309 (9%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+ + D + ++ ++ LG G FG+V ++ T VAV
Sbjct 207 PCLKIQVPAPFDLSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNT-----TPVAV 261
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K LK G + + +E I++ L H +I+ C E + ++ E + GSL++Y
Sbjct 262 KTLKP--GSMDPNDFLREAQIMKNLRHPKLIQLYAVCT--LEDPIYIITELMRHGSLQEY 317
Query 990 LPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
L I L Q + A Q+ GMAYL +++YIHRDLAARNVL+ + K+ DFGLA+
Sbjct 318 LQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLAR 377
Query 1047 AVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + Y R + PV W APE ++ KF SDVWSFG+ LYE++T+
Sbjct 378 VFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGK------ 431
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ MT ++ ++L + RLP+P CP + Y++M CW E RPTFE L
Sbjct 432 --------MPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERPTFETL 483
Query 1166 IPILKTVHE 1174
L+ E
Sbjct 484 RWKLEDYFE 492
>sp|Q922K9|FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus musculus
OX=10090 GN=Frk PE=1 SV=3
Length=512
Score = 315 bits (806), Expect = 3e-94, Method: Composition-based stats.
Identities = 100/459 (22%), Positives = 171/459 (37%), Gaps = 74/459 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VA R + + G + + +L + G +LI S S L+V
Sbjct 112 VAEDRSLQA-EPWFFGAIKRADAEKQLLYSENQTGAFLIRESESQKGDFSLSVLDEG--- 167
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
++ + I + D + F ++ E + C L + CL
Sbjct 168 ------VVKHYRIRRLDEGGFFLTRRKVFSTLNEFVNYYTTT---SDGLCVKLEKPCL-- 216
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ +P L+ +D+ I L LG G V+EG
Sbjct 217 ----------KIQVPTPFDLSYKTADQWEIDRNSIQLLKRLGSGQFGEVWEGLW------ 260
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
V +K L P D F A +M + H L ++
Sbjct 261 -------------------NNTTPVAVKTLKPGSMDPN-DFLREAQIMKSLRHPKLIQLY 300
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHG 733
VC ++TE + HG L +L+ + G + + ++ +A Q+AS ++YLE++N +H
Sbjct 301 AVCTLEDPIYIITELMRHGSLQEYLQNDGGSKIHLIQQVDMAAQVASGMAYLESQNYIHR 360
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLG--------ALSREERVERIPWLAPECLP 785
++ RN+L+ + K++D G+ S+ E + W APE +
Sbjct 361 DLAARNVLVGEHNIY-------KVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIR 413
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLAT 843
N S D W FG L EI G+ P + ++ + +RLP+P +CP Q +
Sbjct 414 T--NKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLSQNYRLPQPSNCPQQFYS 471
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
+ +C EP QRP+F T+ L + + T N
Sbjct 472 IMLECWNVEPKQRPTFETLHWKLEDYFETDCSYSDTNNF 510
Score = 282 bits (722), Expect = 1e-82, Method: Composition-based stats.
Identities = 99/309 (32%), Positives = 152/309 (49%), Gaps = 27/309 (9%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+ + +D + ++ ++ LG G FG+V ++ T VAV
Sbjct 214 PCLKIQVPTPFDLSYKTADQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNT-----TPVAV 268
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K LK G + + +E I+++L H +I+ C E + ++ E + GSL++Y
Sbjct 269 KTLKP--GSMDPNDFLREAQIMKSLRHPKLIQLYAVCT--LEDPIYIITELMRHGSLQEY 324
Query 990 LPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
L I L Q + A Q+ GMAYL +Q+YIHRDLAARNVL+ + K+ DFGLA+
Sbjct 325 LQNDGGSKIHLIQQVDMAAQVASGMAYLESQNYIHRDLAARNVLVGEHNIYKVADFGLAR 384
Query 1047 AVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + Y + + PV W APE ++ KF SDVWSFG+ LYE++T+
Sbjct 385 VFKVDNEDIYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGK------ 438
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ MT ++ ++L + RLP+P CP + Y +M CW E RPTFE L
Sbjct 439 --------MPYSGMTGAQVIQMLSQNYRLPQPSNCPQQFYSIMLECWNVEPKQRPTFETL 490
Query 1166 IPILKTVHE 1174
L+ E
Sbjct 491 HWKLEDYFE 499
>sp|P27446|FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiphophorus
hellerii OX=8084 GN=fyn PE=2 SV=3
Length=537
Score = 312 bits (800), Expect = 3e-93, Method: Composition-based stats.
Identities = 95/465 (20%), Positives = 158/465 (34%), Gaps = 67/465 (14%)
Query 426 LTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYR 482
LT S Y+ P + D G L + +L G YLI S +
Sbjct 125 LTTGGSGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSTGNPRGTYLIRESETTKGA 184
Query 483 LILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGD 542
L++ D + ++ + I + D F ++++L RA
Sbjct 185 FSLSIRDW----DDEKGDHVKHYKIRKLDSGGYYITTRAQFDTLQQLVQHYSD---RAAG 237
Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTN 602
C L C L++ + ++ + + LG G
Sbjct 238 LCCRLVVPCHK-------------GMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGE 284
Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662
V+ G +V +K L P +F E A +M
Sbjct 285 VWMGTWNGT-------------------------TKVAVKTLKPGTMSP-ESFLEEAQIM 318
Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASA 721
++ H L ++ V +VTEY+ G L +L+ G + + + +A Q+A+
Sbjct 319 KKLRHDKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RI 776
++Y+E N +H ++ NIL+ G + K++D G+ E I
Sbjct 378 MAYIERMNYIHRDLRSANILV-------GDNLVCKIADFGLARLIEDNEYTARQGAKFPI 430
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836
W APE G + D W FG L E+ G P + E +R +R+P P
Sbjct 431 KWTAPEAALYG--RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 488
Query 837 S-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
CP L L QC +P +RP+F + L
Sbjct 489 QDCPASLHELMLQCWKKDPEERPTFEYLQAFLEDYFTATEPQYQP 533
Score = 296 bits (758), Expect = 3e-87, Method: Composition-based stats.
Identities = 95/318 (30%), Positives = 148/318 (47%), Gaps = 29/318 (9%)
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
+ P + + D + L+ I+ LG G FG+V + ++ T
Sbjct 239 CCRLVVPCHKGMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGT----- 293
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
VAVK LK G + +E I++ L H+ +++ E+ + +V EY+ G
Sbjct 294 TKVAVKTLKP--GTMSPESFLEEAQIMKKLRHDKLVQLYAVV---SEEPIYIVTEYMSKG 348
Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ ++ + KI D
Sbjct 349 SLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGDNLVCKIAD 408
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ M + E +ERG R+P P CP ++ LM CW+ + RPT
Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPASLHELMLQCWKKDPEERPT 512
Query 1162 FENLIPILKTVHEKYQGQ 1179
FE L L+ + Q
Sbjct 513 FEYLQAFLEDYFTATEPQ 530
>sp|Q9V9J3|SRC42_DROME Tyrosine-protein kinase Src42A OS=Drosophila
melanogaster OX=7227 GN=Src42A PE=1 SV=1
Length=517
Score = 311 bits (796), Expect = 8e-93, Method: Composition-based stats.
Identities = 93/451 (21%), Positives = 165/451 (37%), Gaps = 72/451 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502
+ + KL E G +LI S S L+V D ++ R+
Sbjct 126 EAEPWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRD----GDTVKHYRI 181
Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562
R+ D +F +++EL + C +L + C+ + +
Sbjct 182 RQL-----DEGGFFIARRTTFRTLQELVEHYSKD---SDGLCVNLCKPCVQIEKPVTEGL 233
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
R +D+ + + LG G +V+EG
Sbjct 234 SHRTR------------DQWEIDRTSLKFVRKLGSGQFGDVWEGLW-------------- 267
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
V +K L D F A +M ++ HT L ++ VC
Sbjct 268 -----------NNTTPVAIKTLKSGTMDP-KDFLAEAQIMKKLRHTKLIQLYAVCTVEEP 315
Query 683 NIMVTEYVEHGPLDVWLR---RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRN 739
++TE ++HG L +L+ + + M + +A Q+A+ ++YLE++N +H ++ RN
Sbjct 316 IYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARN 375
Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREE--RVE---RIPWLAPECLPGGANSLSTA 794
+L+ G +K++D G+ E RV I W APE + S
Sbjct 376 VLV-------GDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAA--NYSKFSIK 426
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC--PQLATLTSQCLTYE 852
D W FG L E+ G P + +E + +R+P+P P+L + +C +
Sbjct 427 SDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKD 486
Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
P +RP+F T+ L + +D
Sbjct 487 PMRRPTFETLQWKLEDFYTSDQSDYKEAQAY 517
Score = 276 bits (707), Expect = 2e-80, Method: Composition-based stats.
Identities = 104/321 (32%), Positives = 145/321 (45%), Gaps = 30/321 (9%)
Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923
+ +T D + LK +R LG G FG V ++ T
Sbjct 215 CVNLCKPCVQIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNT---- 270
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
VA+K LK G + E I++ L H +I+ C E+ + ++ E +
Sbjct 271 -TPVAIKTLK--SGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTV--EEPIYIITELMKH 325
Query 984 GSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
GSL +YL S+ + L+ A QI GMAYL +Q+YIHRDLAARNVL+ + +VK
Sbjct 326 GSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVK 385
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
I DFGLA+ + E Y R P+ W APE KF SDVWSFG+ L EL+T+
Sbjct 386 IADFGLARLIKEDE--YEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYG 443
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
I MT + +E G R+P+P C +Y +M CW +
Sbjct 444 R--------------IPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMR 489
Query 1159 RPTFENLIPILKTVHEKYQGQ 1179
RPTFE L L+ + Q
Sbjct 490 RPTFETLQWKLEDFYTSDQSD 510
>sp|Q02977|YRK_CHICK Proto-oncogene tyrosine-protein kinase Yrk
OS=Gallus gallus OX=9031 GN=YRK PE=2 SV=2
Length=536
Score = 311 bits (797), Expect = 8e-93, Method: Composition-based stats.
Identities = 89/457 (19%), Positives = 156/457 (34%), Gaps = 68/457 (15%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + +L G +LI S + L++
Sbjct 137 VAPVDSIQA-EEWYFGKIGRKDAERQLLCHGNCRGTFLIRESETTKGAYSLSIRDW---- 191
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + ++ + I + D F ++++L + RA C L C
Sbjct 192 DEAKGDHVKHYKIRKLDSGGYYITTRAQFDTIQQLVQHY---IERAAGLCCRLAVPCPK- 247
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
L++ + ++ + L LG G V+ G
Sbjct 248 ------------GTPKLADLSVKTKDVWEIPRESLQLLQKLGNGQFGEVWMGTWNGT--- 292
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P AF E A +M ++ H L ++
Sbjct 293 ----------------------TKVAVKTLKPGTMSP-EAFLEEAQIMKRLRHDKLVQLY 329
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTE++ G L +L+ G + + + +A Q+A+ ++Y+E N +H
Sbjct 330 AVVSE-EPIYIVTEFMSQGSLLDFLKDGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHR 388
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 389 DLRAANILV-------GDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALFG- 440
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846
+ D W FG L E+ G P + E +R +R+ P P L +
Sbjct 441 -KFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMQCPGGCPPSLHDVMV 499
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
QC EP +RP+F + L +
Sbjct 500 QCWKREPEERPTFEYLQSFLEDYFTATEPQYQPGDNQ 536
Score = 286 bits (732), Expect = 1e-83, Method: Composition-based stats.
Identities = 96/318 (30%), Positives = 145/318 (46%), Gaps = 29/318 (9%)
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
P + D + L+ ++ LG G FG+V + ++ T
Sbjct 238 CCRLAVPCPKGTPKLADLSVKTKDVWEIPRESLQLLQKLGNGQFGEVWMGTWNGT----- 292
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
VAVK LK G + +E I++ L H+ +++ E+ + +V E++ G
Sbjct 293 TKVAVKTLKP--GTMSPEAFLEEAQIMKRLRHDKLVQLYAVV---SEEPIYIVTEFMSQG 347
Query 985 SLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
SL D+L + L QL+ A QI GMAY+ +YIHRDL A N+L+ ++ + KI D
Sbjct 348 SLLDFLKDGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLVCKIAD 407
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLA+ + + Y R+ P+ W APE KF SDVWSFG+ L EL+T
Sbjct 408 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALFGKFTIKSDVWSFGILLTELVTKGR-- 463
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ M + E +ERG R+ P CP ++ +M CW+ E RPT
Sbjct 464 ------------VPYPGMNNREVLEQVERGYRMQCPGGCPPSLHDVMVQCWKREPEERPT 511
Query 1162 FENLIPILKTVHEKYQGQ 1179
FE L L+ + Q
Sbjct 512 FEYLQSFLEDYFTATEPQ 529
>sp|Q6EWH2|FYNA_DANRE Tyrosine-protein kinase fyna OS=Danio rerio
OX=7955 GN=fyna PE=1 SV=2
Length=537
Score = 310 bits (795), Expect = 2e-92, Method: Composition-based stats.
Identities = 94/465 (20%), Positives = 158/465 (34%), Gaps = 67/465 (14%)
Query 426 LTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYR 482
LT + Y+ P + D G L + +L G +LI S +
Sbjct 125 LTTGGTGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSNGNPRGTFLIRESETTKGA 184
Query 483 LILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGD 542
L++ D + ++ + I + D F ++++L RA
Sbjct 185 YSLSIQDW----DETKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVHHYSA---RAAG 237
Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTN 602
C L C L++ + ++ + + LG G
Sbjct 238 LCCRLIVPCHK-------------GMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGE 284
Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662
V+ G +V +K L P +F E A +M
Sbjct 285 VWMGTWNGN-------------------------TKVAVKTLKPGTMSP-ESFLEEAQIM 318
Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASA 721
++ H L ++ V +VTEY+ G L +L+ G + + + +A Q+A+
Sbjct 319 KKLRHDKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKDGEGRGLKLPNLVDMAAQVAAG 377
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RI 776
++Y+E N +H ++ NIL+ G S K++D G+ E I
Sbjct 378 MAYIERMNYIHRDLRSANILV-------GDSLVCKIADFGLARLIEDNEYTARQGAKFPI 430
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836
W APE G + D W FG L E+ G P + E +R +R+P P
Sbjct 431 KWTAPEAALYG--RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 488
Query 837 S-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
CP L L QC +P +RP+F + L
Sbjct 489 QDCPSSLHELMLQCWKRDPEERPTFEYLQAFLEDYFTATEPQYQP 533
Score = 294 bits (753), Expect = 1e-86, Method: Composition-based stats.
Identities = 94/318 (30%), Positives = 145/318 (46%), Gaps = 29/318 (9%)
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
+ P + + D + L+ I+ LG G FG+V + ++
Sbjct 239 CCRLIVPCHKGMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 293
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
VAVK LK G + +E I++ L H+ +++ E+ + +V EY+ G
Sbjct 294 TKVAVKTLKP--GTMSPESFLEEAQIMKKLRHDKLVQLYAVV---SEEPIYIVTEYMSKG 348
Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
SL D+L + L L+ A Q+ GMAY+ +YIHRDL + N+L+ + + KI D
Sbjct 349 SLLDFLKDGEGRGLKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGDSLVCKIAD 408
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ M + E +ERG R+P P CP ++ LM CW+ + RPT
Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPSSLHELMLQCWKRDPEERPT 512
Query 1162 FENLIPILKTVHEKYQGQ 1179
FE L L+ + Q
Sbjct 513 FEYLQAFLEDYFTATEPQ 530
>sp|P13406|FYN_XENLA Tyrosine-protein kinase Fyn OS=Xenopus laevis
OX=8355 GN=fyn PE=2 SV=3
Length=537
Score = 310 bits (794), Expect = 2e-92, Method: Composition-based stats.
Identities = 93/465 (20%), Positives = 156/465 (34%), Gaps = 67/465 (14%)
Query 426 LTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYR 482
LT + Y+ P + + G L + +L G YLI S +
Sbjct 125 LTTGGTGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTYLIRESETTKGA 184
Query 483 LILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGD 542
L++ D M+ ++ + I + D F ++++L RA
Sbjct 185 YSLSIRDW----DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSE---RAAG 237
Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTN 602
C L C L++ + ++ + + LG G
Sbjct 238 LCCRLVVPCHK-------------GMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGE 284
Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662
V+ G +V +K L P +F E A +M
Sbjct 285 VWMGTWNGN-------------------------TKVAIKTLKPGTMSP-ESFLEEAQIM 318
Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASA 721
++ H L ++ V +VTEY+ G L +L+ G + + + +A Q+A
Sbjct 319 KKLKHDKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVARG 377
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RI 776
++Y+E N +H ++ NIL+ G K++D G+ E I
Sbjct 378 MAYIERMNYIHRDLRSANILV-------GNGLICKIADFGLARLIEDNEYTARQGAKFPI 430
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836
W APE G + D W FG L E+ G P + E +R +R+P P
Sbjct 431 KWTAPEAALYG--RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 488
Query 837 S-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
CP L L C +P +RP+F + L
Sbjct 489 QDCPISLHELMLNCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 533
Score = 292 bits (747), Expect = 9e-86, Method: Composition-based stats.
Identities = 95/318 (30%), Positives = 147/318 (46%), Gaps = 29/318 (9%)
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
+ P + + D + L+ I+ LG G FG+V + ++
Sbjct 239 CCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 293
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
VA+K LK G + +E I++ L H+ +++ E+ + +V EY+ G
Sbjct 294 TKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMSKG 348
Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ N + KI D
Sbjct 349 SLLDFLKDGEGRALKLPNLVDMAAQVARGMAYIERMNYIHRDLRSANILVGNGLICKIAD 408
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ M + E +ERG R+P P CP ++ LM NCW+ + RPT
Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMLNCWKKDPEERPT 512
Query 1162 FENLIPILKTVHEKYQGQ 1179
FE L L+ + Q
Sbjct 513 FEYLQGFLEDYFTATEPQ 530
>sp|P10936|YES_XENLA Tyrosine-protein kinase Yes OS=Xenopus laevis
OX=8355 GN=yes1 PE=2 SV=3
Length=537
Score = 308 bits (790), Expect = 1e-91, Method: Composition-based stats.
Identities = 92/453 (20%), Positives = 159/453 (35%), Gaps = 71/453 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L++
Sbjct 141 VAPADSIQA-EEWYFGKMGRKDAERLLLNPGNQRGTFLVRESETTKGAYSLSIRDW---- 195
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D ++ ++ + I + D F S+++L A C+ L C
Sbjct 196 DEVRGDNVKHYKIRKLDNGGYYITTRAQFESLQKLVKHYSEH---ADGLCYRLTTVCP-- 250
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P+T L++ + ++ + LGQG V+ G
Sbjct 251 -------------SVKPQTQGLAK-DAWEIPRESLRLDVKLGQGCFGEVWIGTWNGT--- 293
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P + AF + A +M ++ H L ++
Sbjct 294 ----------------------TKVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLY 330
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ G + + + +A Q+A ++Y+E N +H
Sbjct 331 AVVSE-EPIYIVTEYMIKGSLLDFLKEGNGKYLKLPQLVDMAAQIADGMAYIERMNYIHR 389
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 390 DLRAANILV-------GDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 441
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 442 -RFTIKSDVWSFGILLTELVAKGRVPYPGMVNREVLEQVERGYRMPCPQRCPESLHELMK 500
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
C +P +RP+F I L
Sbjct 501 LCWKKDPDERPTFEYIQSFLEDYFTATEPQYQP 533
Score = 290 bits (743), Expect = 4e-85, Method: Composition-based stats.
Identities = 96/315 (30%), Positives = 149/315 (47%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ + + A D + L+ LG+G FG+V + ++ T V
Sbjct 242 CYRLTTVCPSVKPQTQGLAKDAWEIPRESLRLDVKLGQGCFGEVWIGTWNGT-----TKV 296
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE I++ L H+ ++ E+ + +V EY+ GSL
Sbjct 297 AIKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEYMIKGSLL 351
Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + + L QL+ A QI +GMAY+ +YIHRDL A N+L+ ++ + KI DFGL
Sbjct 352 DFLKEGNGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGL 411
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+
Sbjct 412 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVAKGR----- 464
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + E +ERG R+P P +CP ++ LMK CW+ + RPTFE
Sbjct 465 ---------VPYPGMVNREVLEQVERGYRMPCPQRCPESLHELMKLCWKKDPDERPTFEY 515
Query 1165 LIPILKTVHEKYQGQ 1179
+ L+ + Q
Sbjct 516 IQSFLEDYFTATEPQ 530
>sp|P09324|YES_CHICK Tyrosine-protein kinase Yes OS=Gallus gallus
OX=9031 GN=YES1 PE=1 SV=3
Length=541
Score = 308 bits (788), Expect = 2e-91, Method: Composition-based stats.
Identities = 91/453 (20%), Positives = 160/453 (35%), Gaps = 71/453 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G++L+ S + L++
Sbjct 145 VAPADSIQA-EEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDW---- 199
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D ++ ++ + I + D F S+++L + A C L C
Sbjct 200 DEVRGDNVKHYKIRKLDNGGYYITTRAQFESLQKLVKHYREH---ADGLCHKLTTVCP-- 254
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P+T L++ + ++ + LGQG V+ G
Sbjct 255 -------------TVKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 297
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P + AF + A +M ++ H L ++
Sbjct 298 ----------------------TKVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLY 334
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTE++ G L +L+ G + + + +A Q+A ++Y+E N +H
Sbjct 335 AVVSE-EPIYIVTEFMTKGSLLDFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHR 393
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 394 DLRAANILV-------GDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 445
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 446 -RFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMK 504
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
C +P +RP+F I L
Sbjct 505 LCWKKDPDERPTFEYIQSFLEDYFTATEPQYQP 537
Score = 294 bits (753), Expect = 2e-86, Method: Composition-based stats.
Identities = 96/315 (30%), Positives = 148/315 (47%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ + + A D + L+ LG+G FG+V + ++ T V
Sbjct 246 CHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT-----TKV 300
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL
Sbjct 301 AIKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEFMTKGSLL 355
Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ ++ + KI DFGL
Sbjct 356 DFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGL 415
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 416 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR----- 468
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + E +ERG R+P P CP ++ LMK CW+ + RPTFE
Sbjct 469 ---------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEY 519
Query 1165 LIPILKTVHEKYQGQ 1179
+ L+ + Q
Sbjct 520 IQSFLEDYFTATEPQ 534
>sp|P13116|SRC2_XENLA Tyrosine-protein kinase Src-2 OS=Xenopus
laevis OX=8355 GN=src-b PE=2 SV=3
Length=532
Score = 307 bits (787), Expect = 2e-91, Method: Composition-based stats.
Identities = 101/453 (22%), Positives = 162/453 (36%), Gaps = 71/453 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L+V+
Sbjct 136 VAPSDSIQA-EEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDY---- 190
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + L ++ + I + D F S+++L A A C L C
Sbjct 191 DASRGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTAVCP-- 245
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
A P+T LS+ + + + LGQG V+ G
Sbjct 246 -------------TAKPQTQGLSK-DAWEIPRDSLRLELKLGQGCFGEVWMGTWNGT--- 288
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
RV +K L P AF + A +M ++ H L ++
Sbjct 289 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 325
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH
Sbjct 326 AVVSE-EPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHR 384
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 385 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 436
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 437 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPDCPESLHDLMF 495
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
QC +P +RP+F + L
Sbjct 496 QCWRKDPEERPTFEYLQAFLEDYFTATEPQYQP 528
Score = 288 bits (738), Expect = 1e-84, Method: Composition-based stats.
Identities = 93/315 (30%), Positives = 143/315 (45%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ + + D + L+ LG+G FG+V + ++ T V
Sbjct 237 CHRLTAVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTR-----V 291
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL
Sbjct 292 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMSKGSLL 346
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 347 DFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 406
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 407 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 459
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P CP ++ LM CW + RPTFE
Sbjct 460 ---------VPYPGMVNREVLDQVERGYRMPCPPDCPESLHDLMFQCWRKDPEERPTFEY 510
Query 1165 LIPILKTVHEKYQGQ 1179
L L+ + Q
Sbjct 511 LQAFLEDYFTATEPQ 525
>sp|P00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src
OS=Gallus gallus OX=9031 GN=SRC PE=1 SV=4
Length=533
Score = 307 bits (787), Expect = 2e-91, Method: Composition-based stats.
Identities = 99/453 (22%), Positives = 163/453 (36%), Gaps = 71/453 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L+V+
Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSD----F 191
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + L ++ + I + D F S+++L A A C L C
Sbjct 192 DNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ P+T L++ + ++ + LGQG V+ G
Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
RV +K L P AF + A +M ++ H L ++
Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 326
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH
Sbjct 327 AVVSE-EPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 496
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
QC +P +RP+F + L
Sbjct 497 QCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQP 529
Score = 289 bits (740), Expect = 8e-85, Method: Composition-based stats.
Identities = 95/315 (30%), Positives = 145/315 (46%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ N+ A D + L+ LG+G FG+V + ++ T V
Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 292
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL
Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMSKGSLL 347
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW + RPTFE
Sbjct 461 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEY 511
Query 1165 LIPILKTVHEKYQGQ 1179
L L+ + Q
Sbjct 512 LQAFLEDYFTSTEPQ 526
>sp|P39688|FYN_MOUSE Tyrosine-protein kinase Fyn OS=Mus musculus
OX=10090 GN=Fyn PE=1 SV=4
Length=537
Score = 307 bits (787), Expect = 2e-91, Method: Composition-based stats.
Identities = 91/453 (20%), Positives = 155/453 (34%), Gaps = 68/453 (15%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G L + +L G +LI S + L++
Sbjct 138 VAPVDSIQA-EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW---- 192
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D M+ ++ + I + D F ++++L RA C L C
Sbjct 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSE---RAAGLCCRLVVPCHK- 248
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
L++ + ++ + + LG G V+ G
Sbjct 249 ------------GMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGN--- 293
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P +F E A +M ++ H L ++
Sbjct 294 ----------------------TKVAIKTLKPGTMSP-ESFLEEAQIMKKLKHDKLVQLY 330
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ G + + + +A Q+A+ ++Y+E N +H
Sbjct 331 AVVSE-EPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G K++D G+ E I W APE G
Sbjct 390 DLRSANILV-------GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 441
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846
+ D W FG L E+ G P + E +R +R+P P CP L L
Sbjct 442 -RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI 500
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
C +P +RP+F + L
Sbjct 501 HCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 533
Score = 289 bits (739), Expect = 1e-84, Method: Composition-based stats.
Identities = 108/438 (25%), Positives = 170/438 (39%), Gaps = 50/438 (11%)
Query 763 GLGALSREERVERIPWLAP-------ECLPGGANSLSTAMDKWGFG-----ATLLEICFD 810
+ E ++AP E G FG + E
Sbjct 122 ARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT 181
Query 811 GE------APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+H+ R+ A + + Q S R
Sbjct 182 KGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETL---QQLVQHYSERAAGL 238
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
+ P + + D + L+ I+ LG G FG+V + ++
Sbjct 239 CCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 293
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
VA+K LK G + +E I++ L H+ +++ E+ + +V EY+ G
Sbjct 294 TKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMSKG 348
Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ N + KI D
Sbjct 349 SLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIAD 408
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ M + E +ERG R+P P CP ++ LM +CW+ + RPT
Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPT 512
Query 1162 FENLIPILKTVHEKYQGQ 1179
FE L L+ + Q
Sbjct 513 FEYLQGFLEDYFTATEPQ 530
>sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo sapiens
OX=9606 GN=FYN PE=1 SV=3
Length=537
Score = 307 bits (787), Expect = 3e-91, Method: Composition-based stats.
Identities = 91/453 (20%), Positives = 155/453 (34%), Gaps = 68/453 (15%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G L + +L G +LI S + L++
Sbjct 138 VAPVDSIQA-EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW---- 192
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D M+ ++ + I + D F ++++L RA C L C
Sbjct 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSE---RAAGLCCRLVVPCHK- 248
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
L++ + ++ + + LG G V+ G
Sbjct 249 ------------GMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGN--- 293
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P +F E A +M ++ H L ++
Sbjct 294 ----------------------TKVAIKTLKPGTMSP-ESFLEEAQIMKKLKHDKLVQLY 330
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ G + + + +A Q+A+ ++Y+E N +H
Sbjct 331 AVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G K++D G+ E I W APE G
Sbjct 390 DLRSANILV-------GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 441
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846
+ D W FG L E+ G P + E +R +R+P P CP L L
Sbjct 442 -RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI 500
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
C +P +RP+F + L
Sbjct 501 HCWKKDPEERPTFEYLQSFLEDYFTATEPQYQP 533
Score = 290 bits (743), Expect = 4e-85, Method: Composition-based stats.
Identities = 108/438 (25%), Positives = 170/438 (39%), Gaps = 50/438 (11%)
Query 763 GLGALSREERVERIPWLAP-------ECLPGGANSLSTAMDKWGFG-----ATLLEICFD 810
+ E ++AP E G FG + E
Sbjct 122 ARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT 181
Query 811 GE------APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+H+ R+ A + + Q S R
Sbjct 182 KGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETL---QQLVQHYSERAAGL 238
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
+ P + + D + L+ I+ LG G FG+V + ++
Sbjct 239 CCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 293
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
VA+K LK G + +E I++ L H+ +++ E+ + +V EY+ G
Sbjct 294 TKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNKG 348
Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ N + KI D
Sbjct 349 SLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIAD 408
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ M + E +ERG R+P P CP ++ LM +CW+ + RPT
Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPT 512
Query 1162 FENLIPILKTVHEKYQGQ 1179
FE L L+ + Q
Sbjct 513 FEYLQSFLEDYFTATEPQ 530
>sp|Q62844|FYN_RAT Tyrosine-protein kinase Fyn OS=Rattus norvegicus
OX=10116 GN=Fyn PE=1 SV=1
Length=537
Score = 307 bits (786), Expect = 3e-91, Method: Composition-based stats.
Identities = 91/453 (20%), Positives = 155/453 (34%), Gaps = 68/453 (15%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G L + +L G +LI S + L++
Sbjct 138 VAPVDSIQA-EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW---- 192
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D M+ ++ + I + D F ++++L RA C L C
Sbjct 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSE---RAAGLCCRLVVPCHK- 248
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
L++ + ++ + + LG G V+ G
Sbjct 249 ------------GMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGN--- 293
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P +F E A +M ++ H L ++
Sbjct 294 ----------------------TKVAIKTLKPGTMSP-ESFLEEAQIMKKLKHDKLVQLY 330
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ G + + + +A Q+A+ ++Y+E N +H
Sbjct 331 AVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G K++D G+ E I W APE G
Sbjct 390 DLRSANILV-------GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 441
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846
+ D W FG L E+ G P + E +R +R+P P CP L L
Sbjct 442 -RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI 500
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
C +P +RP+F + L
Sbjct 501 HCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 533
Score = 289 bits (739), Expect = 1e-84, Method: Composition-based stats.
Identities = 108/438 (25%), Positives = 170/438 (39%), Gaps = 50/438 (11%)
Query 763 GLGALSREERVERIPWLAP-------ECLPGGANSLSTAMDKWGFG-----ATLLEICFD 810
+ E ++AP E G FG + E
Sbjct 122 ARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT 181
Query 811 GE------APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+H+ R+ A + + Q S R
Sbjct 182 KGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETL---QQLVQHYSERAAGL 238
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
+ P + + D + L+ I+ LG G FG+V + ++
Sbjct 239 CCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 293
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
VA+K LK G + +E I++ L H+ +++ E+ + +V EY+ G
Sbjct 294 TKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNKG 348
Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ N + KI D
Sbjct 349 SLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIAD 408
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ M + E +ERG R+P P CP ++ LM +CW+ + RPT
Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPT 512
Query 1162 FENLIPILKTVHEKYQGQ 1179
FE L L+ + Q
Sbjct 513 FEYLQGFLEDYFTATEPQ 530
>sp|A1Y2K1|FYN_PIG Tyrosine-protein kinase Fyn OS=Sus scrofa OX=9823
GN=FYN PE=2 SV=2
Length=537
Score = 307 bits (786), Expect = 3e-91, Method: Composition-based stats.
Identities = 91/453 (20%), Positives = 155/453 (34%), Gaps = 68/453 (15%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G L + +L G +LI S + L++
Sbjct 138 VAPVDSIQA-EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW---- 192
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D M+ ++ + I + D F ++++L RA C L C
Sbjct 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSE---RAAGLCCRLVVPCHK- 248
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
L++ + ++ + + LG G V+ G
Sbjct 249 ------------GMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGN--- 293
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P +F E A +M ++ H L ++
Sbjct 294 ----------------------TKVAIKTLKPGTMSP-ESFLEEAQIMKKLKHDKLVQLY 330
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ G + + + +A Q+A+ ++Y+E N +H
Sbjct 331 AVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G K++D G+ E I W APE G
Sbjct 390 DLRSANILV-------GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 441
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846
+ D W FG L E+ G P + E +R +R+P P CP L L
Sbjct 442 -RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI 500
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
C +P +RP+F + L
Sbjct 501 HCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 533
Score = 289 bits (739), Expect = 1e-84, Method: Composition-based stats.
Identities = 108/438 (25%), Positives = 170/438 (39%), Gaps = 50/438 (11%)
Query 763 GLGALSREERVERIPWLAP-------ECLPGGANSLSTAMDKWGFG-----ATLLEICFD 810
+ E ++AP E G FG + E
Sbjct 122 ARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT 181
Query 811 GE------APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+H+ R+ A + + Q S R
Sbjct 182 KGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETL---QQLVQHYSERAAGL 238
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
+ P + + D + L+ I+ LG G FG+V + ++
Sbjct 239 CCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 293
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
VA+K LK G + +E I++ L H+ +++ E+ + +V EY+ G
Sbjct 294 TKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNKG 348
Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ N + KI D
Sbjct 349 SLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIAD 408
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ M + E +ERG R+P P CP ++ LM +CW+ + RPT
Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPT 512
Query 1162 FENLIPILKTVHEKYQGQ 1179
FE L L+ + Q
Sbjct 513 FEYLQGFLEDYFTATEPQ 530
>sp|A0JNB0|FYN_BOVIN Tyrosine-protein kinase Fyn OS=Bos taurus
OX=9913 GN=FYN PE=2 SV=1
Length=537
Score = 307 bits (786), Expect = 3e-91, Method: Composition-based stats.
Identities = 91/453 (20%), Positives = 155/453 (34%), Gaps = 68/453 (15%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G L + +L G +LI S + L++
Sbjct 138 VAPVDSIQA-EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW---- 192
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D M+ ++ + I + D F ++++L RA C L C
Sbjct 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSE---RAAGLCCRLVVPCHK- 248
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
L++ + ++ + + LG G V+ G
Sbjct 249 ------------GMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGN--- 293
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P +F E A +M ++ H L ++
Sbjct 294 ----------------------TKVAIKTLKPGTMSP-ESFLEEAQIMKKLKHDKLVQLY 330
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ G + + + +A Q+A+ ++Y+E N +H
Sbjct 331 AVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G K++D G+ E I W APE G
Sbjct 390 DLRSANILV-------GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 441
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846
+ D W FG L E+ G P + E +R +R+P P CP L L
Sbjct 442 -RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI 500
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
C +P +RP+F + L
Sbjct 501 HCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 533
Score = 289 bits (739), Expect = 1e-84, Method: Composition-based stats.
Identities = 108/438 (25%), Positives = 170/438 (39%), Gaps = 50/438 (11%)
Query 763 GLGALSREERVERIPWLAP-------ECLPGGANSLSTAMDKWGFG-----ATLLEICFD 810
+ E ++AP E G FG + E
Sbjct 122 ARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT 181
Query 811 GE------APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+H+ R+ A + + Q S R
Sbjct 182 KGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETL---QQLVQHYSERAAGL 238
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
+ P + + D + L+ I+ LG G FG+V + ++
Sbjct 239 CCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 293
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
VA+K LK G + +E I++ L H+ +++ E+ + +V EY+ G
Sbjct 294 TKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNKG 348
Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ N + KI D
Sbjct 349 SLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIAD 408
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ M + E +ERG R+P P CP ++ LM +CW+ + RPT
Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPT 512
Query 1162 FENLIPILKTVHEKYQGQ 1179
FE L L+ + Q
Sbjct 513 FEYLQGFLEDYFTATEPQ 530
>sp|P14084|SRC_AVISS Tyrosine-protein kinase transforming protein
Src OS=Avian sarcoma virus (strain S1) OX=11881 GN=V-SRC
PE=3 SV=3
Length=568
Score = 308 bits (789), Expect = 3e-91, Method: Composition-based stats.
Identities = 100/465 (22%), Positives = 166/465 (36%), Gaps = 71/465 (15%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L+V+
Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSD----F 191
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + L ++ + I + D F S+++L A A C L C
Sbjct 192 DNARGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ P+T L++ + ++ + LGQG V+ G
Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
RV +K L P AF + A +M ++ H L ++
Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVRLY 326
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH
Sbjct 327 AVVSE-EPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 496
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV 891
QC +P +RP+F + L + + D
Sbjct 497 QCWRKDPEERPTFEYLQAFLEDYFTSTEPTAVHMATDPGKYTTAH 541
Score = 289 bits (740), Expect = 2e-84, Method: Composition-based stats.
Identities = 94/307 (31%), Positives = 143/307 (47%), Gaps = 29/307 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ N+ A D + L+ LG+G FG+V + ++ T V
Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 292
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL
Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVRLYAVV---SEEPIYIVTEYMSKGSLL 347
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW + RPTFE
Sbjct 461 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEY 511
Query 1165 LIPILKT 1171
L L+
Sbjct 512 LQAFLED 518
>sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src
OS=Homo sapiens OX=9606 GN=SRC PE=1 SV=3
Length=536
Score = 306 bits (785), Expect = 4e-91, Method: Composition-based stats.
Identities = 100/453 (22%), Positives = 163/453 (36%), Gaps = 71/453 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L+V+
Sbjct 140 VAPSDSIQA-EEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSD----F 194
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + L ++ + I + D F S+++L A A C L C
Sbjct 195 DNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKH---ADGLCHRLTTVCP-- 249
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ P+T L++ + ++ + LGQG V+ G
Sbjct 250 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 292
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
RV +K L P AF + A +M ++ H L ++
Sbjct 293 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 329
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH
Sbjct 330 AVVSE-EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 388
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 389 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 440
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 441 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 499
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
QC EP +RP+F + L
Sbjct 500 QCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQP 532
Score = 289 bits (740), Expect = 9e-85, Method: Composition-based stats.
Identities = 95/315 (30%), Positives = 145/315 (46%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ + A D + L+ LG+G FG+V + ++ T V
Sbjct 241 CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 295
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL
Sbjct 296 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMSKGSLL 350
Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 351 DFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 410
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 411 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 463
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW E RPTFE
Sbjct 464 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEY 514
Query 1165 LIPILKTVHEKYQGQ 1179
L L+ + Q
Sbjct 515 LQAFLEDYFTSTEPQ 529
>sp|Q9TTY2|FER_CANLF Tyrosine-protein kinase Fer OS=Canis lupus
familiaris OX=9615 GN=FER PE=2 SV=1
Length=823
Score = 315 bits (807), Expect = 4e-91, Method: Composition-based stats.
Identities = 93/433 (21%), Positives = 180/433 (42%), Gaps = 80/433 (18%)
Query 447 IRDGIHGPLLEPFVQAK-LRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKF 505
+D HG + P ++A+ L + G +L+ S P +L+V DG + R F
Sbjct 457 EQDWYHGAI--PRIEAQDLLKQQGDFLVRESHGKPGEYVLSVY-----SDGQR----RHF 505
Query 506 PIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMR 565
I+ D + EG G F ++ +L D ++ ++ + S ++++
Sbjct 506 IIQFVDNLYRFEGTG--FSNIPQLI-----------DHHYTTKQVITKK----SGVVLLN 548
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
+ + ++ +++T LG+G VY+G L+
Sbjct 549 P---------IPKDKKWVLNHEDVTLGELLGKGNFGEVYKGILKD--------------- 584
Query 626 PLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+ V +K ++ + F + A ++ Q H ++ + GVC +
Sbjct 585 ----------KTAVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPIY 634
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
++ E V G +LR+++ + + + + AS +SYLE+KN +H ++ RN L+
Sbjct 635 IIMELVPGGDFLSFLRKKKDEIKLKQLVKFSLDAASGMSYLESKNCIHRDLAARNCLV-- 692
Query 745 LGLAEGTSPFIKLSDPGVGL---GALSREERVERIP--WLAPECLPGGANSLSTAMDKWG 799
G + +K+SD G+ G + +++IP W APE L G S+ D W
Sbjct 693 -----GENNVLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYG--RYSSESDVWS 745
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857
FG L E G P + + +R +R+ P+ + + +C Y+P RP
Sbjct 746 FGILLWETFSLGVCPYPGMTNQQATEQVERGYRISAPQHCPEDIFKIMMKCWDYKPENRP 805
Query 858 SFRTILRDLTRLQ 870
F + ++LT ++
Sbjct 806 KFSELQKELTVIK 818
Score = 280 bits (717), Expect = 7e-79, Method: Composition-based stats.
Identities = 94/317 (30%), Positives = 144/317 (45%), Gaps = 25/317 (8%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
I T Q + + P V + + LG+G+FG+V
Sbjct 528 IDHHYTTKQVITKKSGVVLLNPIPKDKKWVLNHEDVTLGELLGKGNFGEVYKGILK---- 583
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VAVK K D + + + QE IL+ H +I+K G C + + + ++ME V
Sbjct 584 -DKTAVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQR--QPIYIIMELV 640
Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P G +L + I L QL+ F+ GM+YL +++ IHRDLAARN L+ + ++KI
Sbjct 641 PGGDFLSFLRKKKDEIKLKQLVKFSLDAASGMSYLESKNCIHRDLAARNCLVGENNVLKI 700
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFG+++ E Y P+ W APE L ++ SDVWSFG+ L+E +
Sbjct 701 SDFGMSRQ--EDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFS--- 755
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L MT + TE +ERG R+ P CP +++ +M CW+ + R
Sbjct 756 -----------LGVCPYPGMTNQQATEQVERGYRISAPQHCPEDIFKIMMKCWDYKPENR 804
Query 1160 PTFENLIPILKTVHEKY 1176
P F L L + +K
Sbjct 805 PKFSELQKELTVIKKKV 821
>sp|P70451|FER_MOUSE Tyrosine-protein kinase Fer OS=Mus musculus
OX=10090 GN=Fer PE=1 SV=2
Length=823
Score = 315 bits (806), Expect = 5e-91, Method: Composition-based stats.
Identities = 92/435 (21%), Positives = 180/435 (41%), Gaps = 80/435 (18%)
Query 447 IRDGIHGPLLEPFVQAK-LRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKF 505
D HG + P ++A+ L + G +L+ S P +L+V DG + R F
Sbjct 458 EHDWYHGAI--PRIEAQELLKQQGDFLVRESHGKPGEYVLSVY-----SDGQR----RHF 506
Query 506 PIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMR 565
I+ D + EG G F ++ +L D F+ ++ + S ++++
Sbjct 507 IIQFVDNLYRFEGTG--FSNIPQLI-----------DHHFNTKQVITKK----SGVVLLN 549
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
+ + ++ ++++ LG+G VY+G L+
Sbjct 550 P---------IPKDKKWVLNHEDVSLGELLGKGNFGEVYKGTLKD--------------- 585
Query 626 PLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+ V +K ++ + F + A ++ Q H ++ + GVC +
Sbjct 586 ----------KTPVAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVY 635
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
++ E V G +LR+ + + + + + +A+ + YLE+KN +H ++ RN L+
Sbjct 636 IIMELVPGGDFLTFLRKRKDELKLKQLVRFSLDVAAGMLYLESKNCIHRDLAARNCLV-- 693
Query 745 LGLAEGTSPFIKLSDPGVGL---GALSREERVERIP--WLAPECLPGGANSLSTAMDKWG 799
G + +K+SD G+ G + +++IP W APE L G S+ D W
Sbjct 694 -----GENNTLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYG--RYSSESDVWS 746
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857
FG L E G P + + +R +R+ P+ ++ T+ +C Y+P RP
Sbjct 747 FGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQNCPEEVFTIMMKCWDYKPENRP 806
Query 858 SFRTILRDLTRLQPH 872
F + ++LT ++
Sbjct 807 KFNDLHKELTVIKKM 821
Score = 277 bits (708), Expect = 1e-77, Method: Composition-based stats.
Identities = 91/315 (29%), Positives = 141/315 (45%), Gaps = 25/315 (8%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
I Q + + P V + + LG+G+FG+V
Sbjct 529 IDHHFNTKQVITKKSGVVLLNPIPKDKKWVLNHEDVSLGELLGKGNFGEVYKGTLK---- 584
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VA+K K D + + + QE IL+ H +I+K G C + + + ++ME V
Sbjct 585 -DKTPVAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQR--QPVYIIMELV 641
Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P G +L + + L QL+ F+ + GM YL +++ IHRDLAARN L+ + +KI
Sbjct 642 PGGDFLTFLRKRKDELKLKQLVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTLKI 701
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFG+++ E Y P+ W APE L ++ SDVWSFG+ L+E +
Sbjct 702 SDFGMSRQ--EDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFS--- 756
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L MT + E +ERG R+ P CP EV+ +M CW+ + R
Sbjct 757 -----------LGVCPYPGMTNQQAREQVERGYRMSAPQNCPEEVFTIMMKCWDYKPENR 805
Query 1160 PTFENLIPILKTVHE 1174
P F +L L + +
Sbjct 806 PKFNDLHKELTVIKK 820
>sp|P14085|SRC_AVIST Tyrosine-protein kinase transforming protein
Src OS=Avian sarcoma virus (strain S2) OX=11882 GN=V-SRC
PE=3 SV=3
Length=557
Score = 307 bits (786), Expect = 6e-91, Method: Composition-based stats.
Identities = 98/439 (22%), Positives = 162/439 (37%), Gaps = 71/439 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L+V+
Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSD----F 191
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + L ++ + I + D F S+++L A A C L C
Sbjct 192 DNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ P+T L++ + ++ + LGQG V+ G
Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
RV +K L P AF + A +M ++ H L ++
Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 326
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH
Sbjct 327 AVVSE-EPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 496
Query 847 QCLTYEPTQRPSFRTILRD 865
QC +P +RP+F +
Sbjct 497 QCWRKDPEERPTFEYLQAF 515
Score = 288 bits (738), Expect = 3e-84, Method: Composition-based stats.
Identities = 94/307 (31%), Positives = 143/307 (47%), Gaps = 29/307 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ N+ A D + L+ LG+G FG+V + ++ T V
Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 292
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL
Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMSKGSLL 347
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW + RPTFE
Sbjct 461 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEY 511
Query 1165 LIPILKT 1171
L L+
Sbjct 512 LQAFLED 518
>sp|P00525|SRC_AVISR Tyrosine-protein kinase transforming protein
Src OS=Avian sarcoma virus (strain rASV1441) OX=11894 GN=V-SRC
PE=1 SV=3
Length=526
Score = 305 bits (782), Expect = 7e-91, Method: Composition-based stats.
Identities = 98/437 (22%), Positives = 162/437 (37%), Gaps = 71/437 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L+V+
Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSD----F 191
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + L ++ + I + D F S+++L A A C L C
Sbjct 192 DNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ P+T L++ + ++ + LGQG V+ G
Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
RV +K L P AF + A +M ++ H L ++
Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 326
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH
Sbjct 327 AVVSE-EPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMC 496
Query 847 QCLTYEPTQRPSFRTIL 863
QC +P +RP+F +
Sbjct 497 QCWRRDPEERPTFEYLQ 513
Score = 284 bits (727), Expect = 5e-83, Method: Composition-based stats.
Identities = 94/305 (31%), Positives = 142/305 (47%), Gaps = 29/305 (10%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ N+ A D + L+ LG+G FG+V + ++ T V
Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 292
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL
Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMSKGSLL 347
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW + RPTFE
Sbjct 461 ---------VPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMCQCWRRDPEERPTFEY 511
Query 1165 LIPIL 1169
L L
Sbjct 512 LQAQL 516
>sp|P63185|SRC_RSVSE Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus subgroup E (strain Schmidt-Ruppin)
OX=270623 GN=V-SRC PE=1 SV=3
Length=526
Score = 305 bits (781), Expect = 1e-90, Method: Composition-based stats.
Identities = 98/437 (22%), Positives = 162/437 (37%), Gaps = 71/437 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L+V+
Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSD----F 191
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + L ++ + I + D F S+++L A A C L C
Sbjct 192 DNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ P+T L++ + ++ + LGQG V+ G
Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
RV +K L P AF + A +M ++ H L ++
Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHKKLVQLY 326
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +V EY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH
Sbjct 327 AVVSE-EPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L S
Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMS 496
Query 847 QCLTYEPTQRPSFRTIL 863
QC +P +RP+F +
Sbjct 497 QCWRRDPEERPTFEYLQ 513
Score = 283 bits (725), Expect = 9e-83, Method: Composition-based stats.
Identities = 93/305 (30%), Positives = 143/305 (47%), Gaps = 29/305 (10%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ N+ A D + L+ LG+G FG+V + ++ T V
Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 292
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L H+ +++ E+ + +V+EY+ GSL
Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHKKLVQLYAVV---SEEPIYIVIEYMSKGSLL 347
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW + RPTFE
Sbjct 461 ---------VPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMSQCWRRDPEERPTFEY 511
Query 1165 LIPIL 1169
L L
Sbjct 512 LQAQL 516
>sp|P15054|SRC_AVIS2 Tyrosine-protein kinase transforming protein
Src OS=Avian sarcoma virus (strain PR2257) OX=11879 GN=V-SRC
PE=3 SV=3
Length=587
Score = 307 bits (786), Expect = 1e-90, Method: Composition-based stats.
Identities = 98/439 (22%), Positives = 162/439 (37%), Gaps = 71/439 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L+V+
Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSD----F 191
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + L ++ + I + D F S+++L A A C L C
Sbjct 192 DNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ P+T L++ + ++ + LGQG V+ G
Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
RV +K L P AF + A +M ++ H L ++
Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 326
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH
Sbjct 327 AVVSE-EPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 496
Query 847 QCLTYEPTQRPSFRTILRD 865
QC +P +RP+F +
Sbjct 497 QCWRKDPEERPTFEYLQAF 515
Score = 291 bits (745), Expect = 6e-85, Method: Composition-based stats.
Identities = 95/318 (30%), Positives = 146/318 (46%), Gaps = 29/318 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ N+ A D + L+ LG+G FG+V + ++ T V
Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 292
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL
Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMSKGSLL 347
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW + RPTFE
Sbjct 461 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEY 511
Query 1165 LIPILKTVHEKYQGQAPS 1182
L L+ + P+
Sbjct 512 LQAFLEDYFTSTEPPVPA 529
>sp|P09760|FER_RAT Tyrosine-protein kinase Fer OS=Rattus norvegicus
OX=10116 GN=Fer PE=1 SV=2
Length=823
Score = 313 bits (803), Expect = 1e-90, Method: Composition-based stats.
Identities = 92/433 (21%), Positives = 179/433 (41%), Gaps = 80/433 (18%)
Query 447 IRDGIHGPLLEPFVQAK-LRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKF 505
D HG + P ++A+ L + G +L+ S P +L+V DG + R F
Sbjct 458 EHDWYHGAI--PRIEAQELLKQQGDFLVRESHGKPGEYVLSVY-----SDGQR----RHF 506
Query 506 PIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMR 565
I+ D + EG G F ++ +L D F+ ++ + S ++++
Sbjct 507 IIQFVDNLYRFEGTG--FSNIPQLI-----------DHHFNTKQVITKK----SGVVLLN 549
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
+ + ++ ++++ LG+G VY+G L+
Sbjct 550 P---------IPKDKKWVLNHEDVSLGELLGKGNFGEVYKGTLKD--------------- 585
Query 626 PLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+ V +K ++ + F + A ++ Q H ++ + GVC +
Sbjct 586 ----------KTPVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVY 635
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
++ E V G +LR+ + + + + + +A+ + YLE KN +H ++ RN L+
Sbjct 636 IIMELVPGGDFLSFLRKRKDELKLKQLVRFSLDVAAGMLYLEGKNCIHRDLAARNCLV-- 693
Query 745 LGLAEGTSPFIKLSDPGVGL---GALSREERVERIP--WLAPECLPGGANSLSTAMDKWG 799
G + +K+SD G+ G + +++IP W APE L G S+ D W
Sbjct 694 -----GENNTLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYG--RYSSESDVWS 746
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857
FG L E G P + + +R +R+ P+ ++ T+ +C Y+P RP
Sbjct 747 FGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQNCPEEIFTIMMKCWDYKPENRP 806
Query 858 SFRTILRDLTRLQ 870
F + ++LT ++
Sbjct 807 KFSDLHKELTAIK 819
Score = 279 bits (714), Expect = 2e-78, Method: Composition-based stats.
Identities = 92/316 (29%), Positives = 141/316 (45%), Gaps = 25/316 (8%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
I Q + + P V + + LG+G+FG+V
Sbjct 529 IDHHFNTKQVITKKSGVVLLNPIPKDKKWVLNHEDVSLGELLGKGNFGEVYKGTLK---- 584
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VAVK K D + + + QE IL+ H +I+K G C + + + ++ME V
Sbjct 585 -DKTPVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQR--QPVYIIMELV 641
Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P G +L + + L QL+ F+ + GM YL ++ IHRDLAARN L+ + +KI
Sbjct 642 PGGDFLSFLRKRKDELKLKQLVRFSLDVAAGMLYLEGKNCIHRDLAARNCLVGENNTLKI 701
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFG+++ E Y P+ W APE L ++ SDVWSFG+ L+E +
Sbjct 702 SDFGMSRQ--EDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFS--- 756
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L MT + E +ERG R+ P CP E++ +M CW+ + R
Sbjct 757 -----------LGVCPYPGMTNQQAREQVERGYRMSAPQNCPEEIFTIMMKCWDYKPENR 805
Query 1160 PTFENLIPILKTVHEK 1175
P F +L L + +K
Sbjct 806 PKFSDLHKELTAIKKK 821
>sp|P05480|SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src
OS=Mus musculus OX=10090 GN=Src PE=1 SV=5
Length=535
Score = 305 bits (780), Expect = 2e-90, Method: Composition-based stats.
Identities = 99/453 (22%), Positives = 163/453 (36%), Gaps = 71/453 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L+V+
Sbjct 139 VAPSDSIQA-EEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSD----F 193
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + L ++ + I + D F S+++L A A C L C
Sbjct 194 DNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKH---ADGLCHRLTTVCP-- 248
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ P+T L++ + ++ + LGQG V+ G
Sbjct 249 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 291
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
RV +K L P AF + A +M ++ H L ++
Sbjct 292 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 328
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ E G + + + ++ Q+AS ++Y+E N VH
Sbjct 329 AVVSE-EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHR 387
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 388 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 439
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 440 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 498
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
QC EP +RP+F + L
Sbjct 499 QCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQP 531
Score = 288 bits (736), Expect = 3e-84, Method: Composition-based stats.
Identities = 94/315 (30%), Positives = 145/315 (46%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ + A D + L+ LG+G FG+V + ++ T V
Sbjct 240 CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 294
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL
Sbjct 295 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMNKGSLL 349
Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + + L QL+ + QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 350 DFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 409
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 410 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 462
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW E RPTFE
Sbjct 463 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEY 513
Query 1165 LIPILKTVHEKYQGQ 1179
L L+ + Q
Sbjct 514 LQAFLEDYFTSTEPQ 528
>sp|Q9WUD9|SRC_RAT Proto-oncogene tyrosine-protein kinase Src
OS=Rattus norvegicus OX=10116 GN=Src PE=1 SV=4
Length=536
Score = 305 bits (780), Expect = 2e-90, Method: Composition-based stats.
Identities = 99/453 (22%), Positives = 163/453 (36%), Gaps = 71/453 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L+V+
Sbjct 140 VAPSDSIQA-EEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSD----F 194
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + L ++ + I + D F S+++L A A C L C
Sbjct 195 DNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKH---ADGLCHRLTTVCP-- 249
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ P+T L++ + ++ + LGQG V+ G
Sbjct 250 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 292
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
RV +K L P AF + A +M ++ H L ++
Sbjct 293 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 329
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ E G + + + ++ Q+AS ++Y+E N VH
Sbjct 330 AVVSE-EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHR 388
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 389 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 440
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 441 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 499
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
QC EP +RP+F + L
Sbjct 500 QCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQP 532
Score = 288 bits (736), Expect = 3e-84, Method: Composition-based stats.
Identities = 94/315 (30%), Positives = 145/315 (46%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ + A D + L+ LG+G FG+V + ++ T V
Sbjct 241 CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 295
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL
Sbjct 296 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMNKGSLL 350
Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + + L QL+ + QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 351 DFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 410
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 411 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 463
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW E RPTFE
Sbjct 464 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEY 514
Query 1165 LIPILKTVHEKYQGQ 1179
L L+ + Q
Sbjct 515 LQAFLEDYFTSTEPQ 529
>sp|P07947|YES_HUMAN Tyrosine-protein kinase Yes OS=Homo sapiens
OX=9606 GN=YES1 PE=1 SV=3
Length=543
Score = 305 bits (780), Expect = 3e-90, Method: Composition-based stats.
Identities = 89/453 (20%), Positives = 159/453 (35%), Gaps = 71/453 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G++L+ S + L++
Sbjct 147 VAPADSIQA-EEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDW---- 201
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D ++ ++ + I + D F ++++L A C L C
Sbjct 202 DEIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEH---ADGLCHKLTTVCP-- 256
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P+T L++ + ++ + LGQG V+ G
Sbjct 257 -------------TVKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 299
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P + AF + A +M ++ H L ++
Sbjct 300 ----------------------TKVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLY 336
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTE++ G L +L+ G + + + +A Q+A ++Y+E N +H
Sbjct 337 AVVSE-EPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHR 395
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 396 DLRAANILV-------GENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 447
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG E+ G P E +R +R+P P CP+ L L +
Sbjct 448 -RFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMN 506
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
C +P +RP+F I L
Sbjct 507 LCWKKDPDERPTFEYIQSFLEDYFTATEPQYQP 539
Score = 289 bits (739), Expect = 2e-84, Method: Composition-based stats.
Identities = 94/315 (30%), Positives = 145/315 (46%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ + + A D + L+ LG+G FG+V + ++ T V
Sbjct 248 CHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT-----TKV 302
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL
Sbjct 303 AIKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEFMSKGSLL 357
Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ + + KI DFGL
Sbjct 358 DFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGL 417
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ EL+T
Sbjct 418 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGR----- 470
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + E +ERG R+P P CP ++ LM CW+ + RPTFE
Sbjct 471 ---------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEY 521
Query 1165 LIPILKTVHEKYQGQ 1179
+ L+ + Q
Sbjct 522 IQSFLEDYFTATEPQ 536
>sp|Q05876|FYN_CHICK Tyrosine-protein kinase Fyn OS=Gallus gallus
OX=9031 GN=FYN PE=1 SV=2
Length=534
Score = 304 bits (779), Expect = 3e-90, Method: Composition-based stats.
Identities = 96/453 (21%), Positives = 164/453 (36%), Gaps = 71/453 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G L + +L G +LI S + L++
Sbjct 138 VAPVDSIQA-EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW---- 192
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D M+ ++ + I + D F ++++L +A CF+L
Sbjct 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSE---KADGLCFNLT------ 243
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ +P+T+ L++ V + + LGQG V+ G
Sbjct 244 ---------VIATNNTPQTVGLAK-DAWEVARDSLFLEQKLGQGCFAEVWRGTWNGN--- 290
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P +F E A +M ++ H L ++
Sbjct 291 ----------------------TKVAIKTLKPGTMSP-ESFLEEAQIMKKLKHDKLVQLY 327
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V R P +VTEY+ G L ++L+ G + + + +A Q+A+ ++Y+E N +H
Sbjct 328 AVVSRRP-IYIVTEYMSKGSLLIFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 386
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G K++D G+ E I W APE G
Sbjct 387 DLRSANILV-------GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 438
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846
+ D W FG L E+ G P + E +R +R+P P CP L L
Sbjct 439 -RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI 497
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
C +P +RP+F + L
Sbjct 498 HCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 530
Score = 278 bits (711), Expect = 9e-81, Method: Composition-based stats.
Identities = 106/432 (25%), Positives = 166/432 (38%), Gaps = 41/432 (9%)
Query 763 GLGALSREERVERIPWLAP-------ECLPGGANSLSTAMDKWGFG-----ATLLEICFD 810
+ E ++AP E G FG + E
Sbjct 122 ARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT 181
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
A S + +H +T++ Q + D
Sbjct 182 KGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSEKADGLCFN 241
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+A T A D + L + LG+G F +V ++ VA+K
Sbjct 242 LTVIATNNTPQTVGLAKDAWEVARDSLFLEQKLGQGCFAEVWRGTWNG-----NTKVAIK 296
Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
LK G + +E I++ L H+ +++ + + +V EY+ GSL +L
Sbjct 297 TLKP--GTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SRRPIYIVTEYMSKGSLLIFL 351
Query 991 PR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ N + KI DFGLA+
Sbjct 352 KDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARL 411
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 412 IEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-------- 461
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ M + E +ERG R+P P CP ++ LM +CW+ + RPTFE L
Sbjct 462 ------VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQG 515
Query 1168 ILKTVHEKYQGQ 1179
L+ + Q
Sbjct 516 FLEDYFTATEPQ 527
>sp|F1RDG9|FYNB_DANRE Tyrosine-protein kinase fynb OS=Danio rerio
OX=7955 GN=fynb PE=2 SV=1
Length=544
Score = 305 bits (780), Expect = 3e-90, Method: Composition-based stats.
Identities = 90/465 (19%), Positives = 155/465 (33%), Gaps = 67/465 (14%)
Query 426 LTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYR 482
LT + Y+ P + D G L + +L G +LI S +
Sbjct 132 LTTGGTGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSTGNPRGTFLIRESETTKGA 191
Query 483 LILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGD 542
L++ D ++ ++ + I + D F ++++L RA
Sbjct 192 FSLSIRDW----DDVKGDHVKHYKIRKLDSGGYYITTRAQFETLQQLVQHYTE---RAAG 244
Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTN 602
C L C L++ + ++ + + LG G
Sbjct 245 LCCRLVVPCHK-------------GMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGE 291
Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662
V+ G +V +K L P +F E A +M
Sbjct 292 VWMGTWNGN-------------------------TKVAIKTLKPGTMSP-ESFLEEAQIM 325
Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASA 721
++ H L ++ V +VTEY+ G L +L+ G + + + +A Q+A
Sbjct 326 KKLRHDKLVQLYAVVSE-EPIYIVTEYMGKGSLLDFLKDGEGRALKLPNLVDMAAQVAGG 384
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RI 776
++Y+E N +H ++ NIL+ G S K++D G+ E I
Sbjct 385 MAYIERMNYIHRDLRSANILV-------GDSLVCKIADFGLARLIEDNEYTARQGAKFPI 437
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--P 834
W APE G + D W FG L E+ G P + E +R +R+ P
Sbjct 438 KWTAPEAALYG--KFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMQCP 495
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
+ L L QC + +RP+F + L
Sbjct 496 QDCPSSLHELMVQCWKKDAEERPTFEYLQAFLEDYFTATEPQYQP 540
Score = 286 bits (732), Expect = 1e-83, Method: Composition-based stats.
Identities = 94/318 (30%), Positives = 146/318 (46%), Gaps = 29/318 (9%)
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
+ P + + D + L+ I+ LG G FG+V + ++
Sbjct 246 CCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 300
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
VA+K LK G + +E I++ L H+ +++ E+ + +V EY+ G
Sbjct 301 TKVAIKTLKP--GTMSPESFLEEAQIMKKLRHDKLVQLYAVV---SEEPIYIVTEYMGKG 355
Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ + + KI D
Sbjct 356 SLLDFLKDGEGRALKLPNLVDMAAQVAGGMAYIERMNYIHRDLRSANILVGDSLVCKIAD 415
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLA+ + + Y R+ P+ W APE KF SDVWSFG+ L EL+T
Sbjct 416 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGKFTIKSDVWSFGILLTELVTKGR-- 471
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ M + E +ERG R+ P CP ++ LM CW+ +A RPT
Sbjct 472 ------------VPYPGMNNREVLEQVERGYRMQCPQDCPSSLHELMVQCWKKDAEERPT 519
Query 1162 FENLIPILKTVHEKYQGQ 1179
FE L L+ + Q
Sbjct 520 FEYLQAFLEDYFTATEPQ 537
>sp|P31693|SRC_RSVPA Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus (strain PA101T) OX=31667 GN=V-SRC
PE=3 SV=3
Length=523
Score = 303 bits (777), Expect = 3e-90, Method: Composition-based stats.
Identities = 113/559 (20%), Positives = 189/559 (34%), Gaps = 82/559 (15%)
Query 328 PVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPAD-RPREPLWAYFCDFRDITHV 386
P + + E S G P + K A F DF V
Sbjct 11 PSQRRRSLEPPDSTHHGGFPASQTPNKTAAPDTHRTPSRSFGTVATELKLFGDFNTSDTV 70
Query 387 VLKEHC------VSIHRQDNKCLELSLPSR-AAALSFVSLVDGYF----RLTADSSHYLC 435
+ V+ +E L + L V+ +G + LT + Y+
Sbjct 71 TSPQRAGALAGSVTTFGTRESRIETDLSFKKRERLQIVNNTEGTWWLAHSLTTGQTGYIP 130
Query 436 HEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQ 492
P + + G + L + G +L+ S + L+V+
Sbjct 131 SNYVAPSDSIQAEEWYFGKITRRESGRLLLNPENPRGTFLVRESETTKGAYCLSVSD--- 187
Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552
D + L ++ + I + D F S+++L A A C L C
Sbjct 188 -FDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP 243
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
+ P+T L++ + ++ + LGQG V+ G
Sbjct 244 ---------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGYFGEVWMGTWNGT- 286
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672
RV +K L P AF + A +M ++ H L
Sbjct 287 ------------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQ 321
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLV 731
++ + +V EY+ G L +L+ E G + + + +A Q+AS ++Y+E N V
Sbjct 322 LYAMVSE-EPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVEMAAQIASGMAYVERMNYV 380
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPG 786
H ++ NIL+ G + K++D G+ E + W APE
Sbjct 381 HRDLRAANILV-------GENLVCKVADFGLARLIEDNEYTARPGARFPVKWTAPEAALY 433
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATL 844
G + D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 434 G--RFTIKSDVWSFGILLTELTTKGRVPYPGMVNGEVLDRVERGYRMPCPPECPESLHDL 491
Query 845 TSQCLTYEPTQRPSFRTIL 863
QC +P +RP+F +
Sbjct 492 MCQCWRKDPEERPTFEYLQ 510
Score = 281 bits (718), Expect = 6e-82, Method: Composition-based stats.
Identities = 95/305 (31%), Positives = 143/305 (47%), Gaps = 29/305 (10%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ N+ A D + L+ LG+G+FG+V + ++ T V
Sbjct 235 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGYFGEVWMGTWNGTTR-----V 289
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL
Sbjct 290 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAMV---SEEPIYIVIEYMSKGSLL 344
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 345 DFLKGEMGKYLRLPQLVEMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 404
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R PV W APE +F SDVWSFG+ L EL T
Sbjct 405 ARLIEDNE--YTARPGARFPVKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 457
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW + RPTFE
Sbjct 458 ---------VPYPGMVNGEVLDRVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEY 508
Query 1165 LIPIL 1169
L L
Sbjct 509 LQAQL 513
>sp|P00524|SRC_RSVSA Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus subgroup A (strain Schmidt-Ruppin)
OX=269446 GN=V-SRC PE=1 SV=6
Length=526
Score = 303 bits (776), Expect = 5e-90, Method: Composition-based stats.
Identities = 97/437 (22%), Positives = 161/437 (37%), Gaps = 71/437 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L+V+
Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSD----F 191
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + L ++ + I + D F S+++L A A C L C
Sbjct 192 DNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ P+T L++ + ++ + LGQG V+ G
Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
RV +K L P AF + A +M ++ H L ++
Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 326
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +V EY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH
Sbjct 327 AVVSE-EPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMC 496
Query 847 QCLTYEPTQRPSFRTIL 863
QC +P +RP+F +
Sbjct 497 QCWRRDPEERPTFEYLQ 513
Score = 283 bits (723), Expect = 2e-82, Method: Composition-based stats.
Identities = 94/305 (31%), Positives = 143/305 (47%), Gaps = 29/305 (10%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ N+ A D + L+ LG+G FG+V + ++ T V
Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 292
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL
Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVIEYMSKGSLL 347
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW + RPTFE
Sbjct 461 ---------VPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMCQCWRRDPEERPTFEY 511
Query 1165 LIPIL 1169
L L
Sbjct 512 LQAQL 516
>sp|P17713|STK_HYDVU Tyrosine-protein kinase STK OS=Hydra vulgaris
OX=6087 GN=STK PE=2 SV=1
Length=509
Score = 302 bits (774), Expect = 6e-90, Method: Composition-based stats.
Identities = 97/486 (20%), Positives = 174/486 (36%), Gaps = 78/486 (16%)
Query 393 VSIHRQDNKCLELSLPSRAAALSFVSLVDG---YFR-LTADSSHYLCHEVAPPRLVMSIR 448
V+++ + + E + L ++ DG Y R L +S Y+ P
Sbjct 65 VALYDYEARISEDLSFKKGERLQIINTADGDWWYARSLITNSEGYIPSTYVAPEKSYEAE 124
Query 449 DGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKF 505
+ G + + +L G +LI + + L+V D ++ R+RK
Sbjct 125 EWYFGDVKRAEAEKRLMVRGLPSGTFLIRKAETAVGNFSLSVRD----GDSVKHYRVRKL 180
Query 506 PIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMR 565
D F S+ EL A +L C
Sbjct 181 -----DTGGYFITTRAPFNSLYELVQHYTKD---ADGLVCALTLPCP------------- 219
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
+ P T +++ + ++ + LG G V+ G
Sbjct 220 --KDKPVTGGIAK-DAWEIPRESLRLNRKLGAGQFGEVWAGVW----------------- 259
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
+V +K L P A +F + A +M ++ H HL ++ +C +
Sbjct 260 --------NNTTQVAVKTLKPGTMSPA-SFLDEAGVMKKLRHKHLVQLYAICSDREPIYI 310
Query 686 VTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
VTEY+ G L +L + G ++ + + +A Q+AS +++LE + +H ++ RNIL+
Sbjct 311 VTEYMSGGSLLDYLSKGEGVNLQLPTLIDMAAQVASGMAFLEAQGYIHRDLAARNILV-- 368
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWG 799
G + K++D G+ E I W APE N + D W
Sbjct 369 -----GENYICKVADFGLARLIEDDEYTAHEGAKFPIKWTAPEAAL--YNRFTIKSDVWS 421
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRP 857
FG + EI G P + ++ ++ +R+P CP L + Q +P RP
Sbjct 422 FGILMAEIVTKGRIPYPGMTNAQTIAEVEKGYRMPIMPGCPEPLYNIMLQTWNKDPENRP 481
Query 858 SFRTIL 863
+F +
Sbjct 482 TFDYLQ 487
Score = 277 bits (709), Expect = 9e-81, Method: Composition-based stats.
Identities = 93/285 (33%), Positives = 143/285 (50%), Gaps = 28/285 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ L+ R LG G FG+V ++ T VAVK LK G + + E
Sbjct 233 WEIPRESLRLNRKLGAGQFGEVWAGVWNNT-----TQVAVKTLKP--GTMSPASFLDEAG 285
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQ 1006
+++ L H+H+++ C D+ + + +V EY+ GSL DYL + ++ L L+ A Q
Sbjct 286 VMKKLRHKHLVQLYAICSDR--EPIYIVTEYMSGGSLLDYLSKGEGVNLQLPTLIDMAAQ 343
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+ GMA+L AQ YIHRDLAARN+L+ + + K+ DFGLA+ + + Y E P+
Sbjct 344 VASGMAFLEAQGYIHRDLAARNILVGENYICKVADFGLARLIEDDE--YTAHEGAKFPIK 401
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE +F SDVWSFG+ + E++T I MT +
Sbjct 402 WTAPEAALYNRFTIKSDVWSFGILMAEIVTKGR--------------IPYPGMTNAQTIA 447
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+E+G R+P CP +Y++M W + RPTF+ L +L+
Sbjct 448 EVEKGYRMPIMPGCPEPLYNIMLQTWNKDPENRPTFDYLQGVLED 492
>sp|A1A5H8|YES_DANRE Tyrosine-protein kinase yes OS=Danio rerio
OX=7955 GN=yes1 PE=1 SV=1
Length=546
Score = 303 bits (777), Expect = 7e-90, Method: Composition-based stats.
Identities = 91/453 (20%), Positives = 158/453 (35%), Gaps = 71/453 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L++
Sbjct 150 VAPADSIQA-EEWYFGKMGRKDAERLLLLPGNQRGTFLVRESETTKGAYSLSIRDW---- 204
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D M+ ++ + I + D F ++++L A C+ L C
Sbjct 205 DEMKGDNVKHYKIRKLDSGGYYITTRAQFDTLQKLVKHYTEH---ADGLCYRLTTVCP-- 259
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P+T L++ + ++ + LGQG V+ G
Sbjct 260 -------------TVKPQTQGLAK-DAWEIPRESLRLELKLGQGCFGEVWMGTWNGT--- 302
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P AF + A +M ++ H L ++
Sbjct 303 ----------------------TKVAIKTLKPGTMSP-EAFLQEAQIMKKLRHDKLVPLY 339
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ G + + + +A Q+A ++++E N +H
Sbjct 340 AVVSE-EPIYIVTEYMGKGSLLDFLKEGEGKYLKLPQLVDMAAQIADGMAFIERMNYIHR 398
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 399 DLRAANILV-------GDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 450
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L +
Sbjct 451 -RFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHEMMR 509
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
C EP +RP+F I L
Sbjct 510 LCWKKEPDERPTFEYIQSFLEDYFTATEPQYQP 542
Score = 290 bits (741), Expect = 7e-85, Method: Composition-based stats.
Identities = 95/315 (30%), Positives = 148/315 (47%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ + + A D + L+ LG+G FG+V + ++ T V
Sbjct 251 CYRLTTVCPTVKPQTQGLAKDAWEIPRESLRLELKLGQGCFGEVWMGTWNGT-----TKV 305
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE I++ L H+ ++ E+ + +V EY+ GSL
Sbjct 306 AIKTLKP--GTMSPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEYMGKGSLL 360
Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI +GMA++ +YIHRDL A N+L+ ++ + KI DFGL
Sbjct 361 DFLKEGEGKYLKLPQLVDMAAQIADGMAFIERMNYIHRDLRAANILVGDNLVCKIADFGL 420
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 421 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR----- 473
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + E +ERG R+P P CP ++ +M+ CW+ E RPTFE
Sbjct 474 ---------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHEMMRLCWKKEPDERPTFEY 524
Query 1165 LIPILKTVHEKYQGQ 1179
+ L+ + Q
Sbjct 525 IQSFLEDYFTATEPQ 539
>sp|P00527|YES_AVISY Tyrosine-protein kinase transforming protein
Yes (Fragment) OS=Y73 avian sarcoma virus OX=11884 GN=V-YES
PE=3 SV=2
Length=528
Score = 303 bits (776), Expect = 7e-90, Method: Composition-based stats.
Identities = 89/439 (20%), Positives = 158/439 (36%), Gaps = 71/439 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G++L+ S + L++
Sbjct 137 VAPADSIEA-EEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDW---- 191
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D ++ ++ + I + D F S+++L + A C L C
Sbjct 192 DEVRGDNVKHYKIRKLDNGGYYITTRAQFESLQKLVKHSREH---ADGLCHKLTTVCP-- 246
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P+T L++ + ++ + LGQG V+ G
Sbjct 247 -------------TVKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L + AF + A +M ++ H L ++
Sbjct 290 ----------------------TKVAIKTLKLGTM-MPEAFLQEAQIMKKLRHDKLVPLY 326
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTE++ G L +L+ G + + + +A Q+A ++Y+E N +H
Sbjct 327 AVVSE-EPIYIVTEFMTKGSLLDFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHR 385
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 386 DLRAANILV-------GDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 438 -RFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMK 496
Query 847 QCLTYEPTQRPSFRTILRD 865
C +P +RP+F I
Sbjct 497 LCWKKDPDERPTFEYIQSF 515
Score = 293 bits (751), Expect = 2e-86, Method: Composition-based stats.
Identities = 95/307 (31%), Positives = 146/307 (48%), Gaps = 29/307 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ + + A D + L+ LG+G FG+V + ++ T V
Sbjct 238 CHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT-----TKV 292
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL
Sbjct 293 AIKTLKL--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEFMTKGSLL 347
Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ ++ + KI DFGL
Sbjct 348 DFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + E +ERG R+P P CP ++ LMK CW+ + RPTFE
Sbjct 461 ---------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEY 511
Query 1165 LIPILKT 1171
+ L+
Sbjct 512 IQSFLED 518
>sp|P27447|YES_XIPHE Tyrosine-protein kinase Yes OS=Xiphophorus
hellerii OX=8084 GN=yes PE=2 SV=3
Length=544
Score = 303 bits (776), Expect = 9e-90, Method: Composition-based stats.
Identities = 95/453 (21%), Positives = 156/453 (34%), Gaps = 71/453 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + S + G L + L E G +LI S + L++
Sbjct 148 VAPADSIQS-EEWYFGKLSRKDTERLLLLPGNERGTFLIRESETTKGAYSLSLRDW---- 202
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + + + I + D F S++ L C+ L C
Sbjct 203 DETKGDNCKHYKIRKLDNGGYYITTRTQFMSLQMLVKHYTEH---VDGLCYKLTTVCP-- 257
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ P+T +++ + ++ + LGQG V+ G
Sbjct 258 -------------QVKPQTQGIAK-DAWEIPRESLRLDVRLGQGCFGEVWMGTWNGT--- 300
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P AF E A +M ++ H L ++
Sbjct 301 ----------------------TKVAIKTLKPGTMSP-EAFLEEAQIMKKLRHDKLVPLY 337
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTE++ G L +L+ G H+ + + +A Q+A ++++E N +H
Sbjct 338 AVVSE-EPIYIVTEFMGKGSLLDFLKEGDGKHLKLPQLVDMASQIADGMAFIERMNYIHR 396
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+A + K++D G+ E I W APE G
Sbjct 397 DLRAANILVA-------DNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 448
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E R +R+P P CP+ L +
Sbjct 449 -RFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVDRGYRMPCPQGCPESLHEMMR 507
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
QC EP +RP+F I L
Sbjct 508 QCWKKEPDERPTFEYIQSFLEDYFTATEPQYQP 540
Score = 288 bits (736), Expect = 3e-84, Method: Composition-based stats.
Identities = 92/315 (29%), Positives = 148/315 (47%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ + + A D + L+ LG+G FG+V + ++ T V
Sbjct 249 CYKLTTVCPQVKPQTQGIAKDAWEIPRESLRLDVRLGQGCFGEVWMGTWNGT-----TKV 303
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + +E I++ L H+ ++ E+ + +V E++ GSL
Sbjct 304 AIKTLKP--GTMSPEAFLEEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEFMGKGSLL 358
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI +GMA++ +YIHRDL A N+L+ ++ + KI DFGL
Sbjct 359 DFLKEGDGKHLKLPQLVDMASQIADGMAFIERMNYIHRDLRAANILVADNLVCKIADFGL 418
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 419 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR----- 471
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + E ++RG R+P P CP ++ +M+ CW+ E RPTFE
Sbjct 472 ---------VPYPGMVNREVLEQVDRGYRMPCPQGCPESLHEMMRQCWKKEPDERPTFEY 522
Query 1165 LIPILKTVHEKYQGQ 1179
+ L+ + Q
Sbjct 523 IQSFLEDYFTATEPQ 537
>sp|Q04736|YES_MOUSE Tyrosine-protein kinase Yes OS=Mus musculus
OX=10090 GN=Yes1 PE=1 SV=3
Length=541
Score = 303 bits (776), Expect = 1e-89, Method: Composition-based stats.
Identities = 86/443 (19%), Positives = 154/443 (35%), Gaps = 70/443 (16%)
Query 448 RDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
+ G + + L + G++L+ S + L++ D ++ ++
Sbjct 154 EEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDW----DEVRGDNVKH 209
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ I + D F ++++L A C L C
Sbjct 210 YKIRKLDNGGYYITTRAQFDTLQKLVKHYTEH---ADGLCHKLTTVCP------------ 254
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
P+T L++ + ++ + LGQG V+ G
Sbjct 255 ---TVKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT------------- 297
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+V +K L P + AF + A +M ++ H L ++ V
Sbjct 298 ------------TKVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLYAVVSE-EPIY 343
Query 685 MVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+VTE++ G L +L+ G + + + +A Q+A ++Y+E N +H ++ NIL+
Sbjct 344 IVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILV- 402
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKW 798
G + K++D G+ E I W APE G + D W
Sbjct 403 ------GENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG--RFTIKSDVW 454
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQR 856
FG E+ G P E +R +R+P P CP+ L L + C +P +R
Sbjct 455 SFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDER 514
Query 857 PSFRTILRDLTRLQPHNLADVLT 879
P+F I L
Sbjct 515 PTFEYIQSFLEDYFTATEPQYQP 537
Score = 288 bits (738), Expect = 2e-84, Method: Composition-based stats.
Identities = 94/315 (30%), Positives = 145/315 (46%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ + + A D + L+ LG+G FG+V + ++ T V
Sbjct 246 CHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT-----TKV 300
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL
Sbjct 301 AIKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEFMSKGSLL 355
Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ + + KI DFGL
Sbjct 356 DFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLICKIADFGL 415
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ EL+T
Sbjct 416 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGR----- 468
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + E +ERG R+P P CP ++ LM CW+ + RPTFE
Sbjct 469 ---------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEY 519
Query 1165 LIPILKTVHEKYQGQ 1179
+ L+ + Q
Sbjct 520 IQSFLEDYFTATEPQ 534
>sp|Q1JPZ3|SRC_DANRE Proto-oncogene tyrosine-protein kinase Src
OS=Danio rerio OX=7955 GN=src PE=1 SV=2
Length=534
Score = 302 bits (774), Expect = 1e-89, Method: Composition-based stats.
Identities = 97/465 (21%), Positives = 158/465 (34%), Gaps = 70/465 (15%)
Query 426 LTADSSHYLCHEVAPPRLVMSIRDGIHGPLL---EPFVQAKLRPEDGLYLIHWSTSHPYR 482
LT S Y+ P + + G + + L G +L+ S +
Sbjct 125 LTTGESGYIPSNYVAPSDSIQAEEWYFGKITRRDSERLLLNLENRRGTFLVRESETTKGA 184
Query 483 LILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGD 542
L+V D ++ L ++ + I + D F ++++L + A
Sbjct 185 YCLSVLDY----DNVKGLNVKHYKIRKLDSGGFYITSRTQFSTLQQLVNHYRQH---ADG 237
Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTN 602
C SL C P T L++ + + + LGQG
Sbjct 238 LCHSLTDVCP---------------VLKPPTQGLAR-DAWEIPRDSLRLDVKLGQGCFGE 281
Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662
V+ G RV +K L P AF + A +M
Sbjct 282 VWMGTWNGT-------------------------TRVAIKTLKPGTMSP-EAFLQEAQVM 315
Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASA 721
++ H L ++ V +VTEY+ G L +L+ + G + + + +A Q+AS
Sbjct 316 KKLRHEKLVQLYAVVSE-EPIYIVTEYMGQGSLLDFLKGDMGKMLRLPQLVDMASQIASG 374
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RI 776
++Y+E N VH ++ NIL+ G + K++D G+ E I
Sbjct 375 MAYVERMNYVHRDLRAANILV-------GDNLVCKVADFGLARLIEDNEYTARQGAKFPI 427
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836
W APE G + D W FG L E+ G P E +R +R+P P
Sbjct 428 KWTAPEAALYG--RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCP 485
Query 837 --SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
L L C EP +RP+F + L
Sbjct 486 AECPDSLHELMLTCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQP 530
Score = 283 bits (723), Expect = 2e-82, Method: Composition-based stats.
Identities = 97/315 (31%), Positives = 147/315 (47%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
++ VL A D + L+ LG+G FG+V + ++ T V
Sbjct 239 CHSLTDVCPVLKPPTQGLARDAWEIPRDSLRLDVKLGQGCFGEVWMGTWNGTTR-----V 293
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL
Sbjct 294 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMGQGSLL 348
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ ++ + K+ DFGL
Sbjct 349 DFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGL 408
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 409 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 461
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW E RPTFE
Sbjct 462 ---------VPYPGMVNREVLDQVERGYRMPCPAECPDSLHELMLTCWRKEPEERPTFEY 512
Query 1165 LIPILKTVHEKYQGQ 1179
L L+ + Q
Sbjct 513 LQGFLEDYFTSTEPQ 527
>sp|P13115|SRC1_XENLA Tyrosine-protein kinase Src-1 OS=Xenopus
laevis OX=8355 GN=src-a PE=2 SV=4
Length=532
Score = 302 bits (773), Expect = 2e-89, Method: Composition-based stats.
Identities = 101/453 (22%), Positives = 162/453 (36%), Gaps = 71/453 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L+V+
Sbjct 136 VAPSDSIQA-EEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDY---- 190
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + L ++ + I + D F S+++L A A C L C
Sbjct 191 DANRGLNVKHYKIRKLDSGGFYITSRTQFISLQQLVAYYSKH---ADGLCHRLTTVCP-- 245
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
A P+T LS+ + + + LGQG V+ G
Sbjct 246 -------------TAKPQTQGLSR-DAWEIPRDSLRLELKLGQGCFGEVWMGTWNGT--- 288
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
RV +K L P AF + A +M ++ H L ++
Sbjct 289 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 325
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH
Sbjct 326 AVVSE-EPIYIVTEYISKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHR 384
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 385 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 436
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 437 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPDCPESLHDLMF 495
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
QC +P +RP+F + L
Sbjct 496 QCWRKDPEERPTFEYLQAFLEDYFTATEPQYQP 528
Score = 286 bits (732), Expect = 1e-83, Method: Composition-based stats.
Identities = 93/315 (30%), Positives = 143/315 (45%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ + + D + L+ LG+G FG+V + ++ T V
Sbjct 237 CHRLTTVCPTAKPQTQGLSRDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTR-----V 291
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL
Sbjct 292 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYISKGSLL 346
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 347 DFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 406
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 407 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 459
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P CP ++ LM CW + RPTFE
Sbjct 460 ---------VPYPGMVNREVLDQVERGYRMPCPPDCPESLHDLMFQCWRKDPEERPTFEY 510
Query 1165 LIPILKTVHEKYQGQ 1179
L L+ + Q
Sbjct 511 LQAFLEDYFTATEPQ 525
>sp|Q6P6U0|FGR_RAT Tyrosine-protein kinase Fgr OS=Rattus norvegicus
OX=10116 GN=Fgr PE=1 SV=1
Length=517
Score = 301 bits (770), Expect = 3e-89, Method: Composition-based stats.
Identities = 92/456 (20%), Positives = 160/456 (35%), Gaps = 71/456 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + +L + G +LI S + L++ Q
Sbjct 121 VAPVDSIQA-EEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQN- 178
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
+ ++ + I + D F SV++L C+ L C+
Sbjct 179 ---RGDHIKHYKIRKLDMGGYYITTRAQFESVQDLVRHYMEVN---DGLCYLLTAPCM-- 230
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P+TL L++ +D+ I LG G +V+ G
Sbjct 231 -------------VMKPQTLGLAK-DAWEIDRNSIALDRRLGTGCFGDVWLGTWNCS--- 273
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P AF E A +M + H L ++
Sbjct 274 ----------------------TKVAVKTLKPGTMSP-KAFLEEAQIMKLLRHDKLVQLY 310
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTE++ +G L +L+ +GH + + + +A Q+A ++Y+E N +H
Sbjct 311 AVVSE-EPIYIVTEFMCYGSLLDFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHR 369
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIPWLAPECLPGGA 788
++ NIL+ G K++D G+ + E I W APE G
Sbjct 370 DLRAANILV-------GEHLICKIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFG- 421
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846
+ D W FG L E+ G P + E + + +P P CP L +
Sbjct 422 -RFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPVSLYEVME 480
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
Q +P +RP+F + L +
Sbjct 481 QTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQPGDQ 516
Score = 271 bits (692), Expect = 2e-78, Method: Composition-based stats.
Identities = 93/315 (30%), Positives = 141/315 (45%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
V+ A D + + R LG G FG V L ++ + V
Sbjct 222 CYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRRLGTGCFGDVWLGTWNCS-----TKV 276
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
AVK LK G + +E I++ L H+ +++ E+ + +V E++ GSL
Sbjct 277 AVKTLKP--GTMSPKAFLEEAQIMKLLRHDKLVQLYAVV---SEEPIYIVTEFMCYGSLL 331
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L H++ L L+ A Q+ EGMAY+ +YIHRDL A N+L+ + KI DFGL
Sbjct 332 DFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLICKIADFGL 391
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y ++ P+ W APE +F SDVWSFG+ L EL+T
Sbjct 392 ARLIVDDE--YNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGR----- 444
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + E +E G +P P CP +Y +M+ W + RPTFE
Sbjct 445 ---------VPYPGMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEY 495
Query 1165 LIPILKTVHEKYQGQ 1179
L L+ + Q
Sbjct 496 LQSFLEDYFTSTEPQ 510
>sp|F1LM93|YES_RAT Tyrosine-protein kinase Yes OS=Rattus norvegicus
OX=10116 GN=Yes1 PE=1 SV=1
Length=541
Score = 301 bits (770), Expect = 6e-89, Method: Composition-based stats.
Identities = 89/453 (20%), Positives = 159/453 (35%), Gaps = 71/453 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G++L+ S + L++
Sbjct 145 VAPADSIQA-EEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDW---- 199
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D ++ ++ + I + D F ++++L A C L C
Sbjct 200 DEVRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEH---ADGLCHKLTTVCP-- 254
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P+T L++ + ++ + LGQG V+ G
Sbjct 255 -------------TVKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 297
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P + AF + A +M ++ H L ++
Sbjct 298 ----------------------TKVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLY 334
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTE++ G L +L+ G + + + +A Q+A ++Y+E N +H
Sbjct 335 AVVSE-EPIYIVTEFMSKGILLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHR 393
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 394 DLRAANILV-------GENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 445
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG E+ G P E +R +R+P P CP+ L L +
Sbjct 446 -RFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMN 504
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
C +P +RP+F I L
Sbjct 505 LCWKKDPDERPTFEYIQSFLEDYFTATEPQYQP 537
Score = 285 bits (729), Expect = 4e-83, Method: Composition-based stats.
Identities = 93/315 (30%), Positives = 144/315 (46%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ + + A D + L+ LG+G FG+V + ++ T V
Sbjct 246 CHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT-----TKV 300
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE I++ L H+ ++ E+ + +V E++ G L
Sbjct 301 AIKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEFMSKGILL 355
Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ + + KI DFGL
Sbjct 356 DFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGL 415
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ EL+T
Sbjct 416 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGR----- 468
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + E +ERG R+P P CP ++ LM CW+ + RPTFE
Sbjct 469 ---------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEY 519
Query 1165 LIPILKTVHEKYQGQ 1179
+ L+ + Q
Sbjct 520 IQSFLEDYFTATEPQ 534
>sp|P14234|FGR_MOUSE Tyrosine-protein kinase Fgr OS=Mus musculus
OX=10090 GN=Fgr PE=1 SV=2
Length=517
Score = 299 bits (766), Expect = 1e-88, Method: Composition-based stats.
Identities = 89/456 (20%), Positives = 155/456 (34%), Gaps = 71/456 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + +L G +LI S + L++ Q
Sbjct 121 VAPVDSIQA-EEWYFGKISRKDAERQLLSSGNPQGAFLIRESETTKGAYSLSIRDWDQN- 178
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
+ ++ + I + D F S+++L C+ L C
Sbjct 179 ---RGDHIKHYKIRKLDTGGYYITTRAQFDSIQDLVRHYMEVN---DGLCYLLTAPC--- 229
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P+TL L++ +D+ I LG G +V+ G
Sbjct 230 ------------TTTKPQTLGLAK-DAWEIDRNSIALERRLGTGCFGDVWLGTWNCS--- 273
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P AF E A +M + H L ++
Sbjct 274 ----------------------TKVAVKTLKPGTMSP-KAFLEEAQIMKLLRHDKLVQLY 310
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTE++ +G L +L+ G + + + +A Q+A ++Y+E N +H
Sbjct 311 AVVSE-EPIYIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQVAEGMAYMERMNYIHR 369
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIPWLAPECLPGGA 788
++ NIL+ + K++D G+ E I W APE G
Sbjct 370 DLRAANILVGEYLI-------CKIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFG- 421
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846
+ D W FG L E+ G P + E + + +P P CP L +
Sbjct 422 -RFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEVME 480
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
Q +P +RP+F + L +
Sbjct 481 QAWRLDPEERPTFEYLQSFLEDYFTSTEPQYQPGDQ 516
Score = 268 bits (686), Expect = 1e-77, Method: Composition-based stats.
Identities = 89/293 (30%), Positives = 136/293 (46%), Gaps = 29/293 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ + R LG G FG V L ++ + VAVK LK G + +E
Sbjct 244 WEIDRNSIALERRLGTGCFGDVWLGTWNCS-----TKVAVKTLKP--GTMSPKAFLEEAQ 296
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQ 1006
I++ L H+ +++ E+ + +V E++ GSL D+L ++ L L+ A Q
Sbjct 297 IMKLLRHDKLVQLYAVV---SEEPIYIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQ 353
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+ EGMAY+ +YIHRDL A N+L+ + KI DFGLA+ + + Y ++ P+
Sbjct 354 VAEGMAYMERMNYIHRDLRAANILVGEYLICKIADFGLARLIEDNE--YNPQQGTKFPIK 411
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE +F SDVWSFG+ L EL+T + M + E
Sbjct 412 WTAPEAALFGRFTVKSDVWSFGILLTELITKGR--------------VPYPGMNNREVLE 457
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+E G +P P CP +Y +M+ W + RPTFE L L+ + Q
Sbjct 458 QVEHGYHMPCPPGCPASLYEVMEQAWRLDPEERPTFEYLQSFLEDYFTSTEPQ 510
>sp|P10447|ABL_FSVHY Tyrosine-protein kinase transforming protein
Abl OS=Feline sarcoma virus (strain Hardy-Zuckerman 2) OX=11776
GN=ABL PE=2 SV=1
Length=439
Score = 296 bits (758), Expect = 2e-88, Method: Composition-based stats.
Identities = 95/428 (22%), Positives = 157/428 (37%), Gaps = 70/428 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
HGP+ + L +G +L+ S S P + +++ R+
Sbjct 72 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG---------RVYH 122
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ I + F ++ EL A +L
Sbjct 123 YRINTASDGKLYVSPESRFNTLAELVHH---HSTVADGLITTLHYPAPK----------- 168
Query 565 RGARASPRTLNLSQ-LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
R P +S +++ +IT LG G VYEG +
Sbjct 169 ---RNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYS----------- 214
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
L V +K L ++ F + A++M ++ H +L + GVC R P
Sbjct 215 -------------LTVAVKTLKEDTMEV-EEFLKEAAVMKEIKHPNLVQLLGVCTREPPF 260
Query 684 IMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
++TE++ +G L +LR R V + +A Q++SA+ YLE KN +H ++ RN L+
Sbjct 261 YIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV 320
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDK 797
G + +K++D G+ I W APE L N S D
Sbjct 321 -------GENHLVKVADFGLSRLMTGDTYTAHAGTKFPIKWTAPESLA--YNKFSIKSDV 371
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855
W FG L EI G +P S+ ++ +R+ PE ++ L C + P+
Sbjct 372 WAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSD 431
Query 856 RPSFRTIL 863
RP+F I
Sbjct 432 RPAFAEIH 439
Score = 280 bits (715), Expect = 1e-82, Method: Composition-based stats.
Identities = 94/300 (31%), Positives = 143/300 (48%), Gaps = 27/300 (9%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
P + TV SP D + + LG G +G+V + + VA
Sbjct 163 HYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSL----TVA 218
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
VK LK D + +E +++ + H ++++ G C E ++ E++ G+L D
Sbjct 219 VKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLD 274
Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
YL R + LL A QI M YL +++IHRDLAARN L+ + LVK+ DFGL+
Sbjct 275 YLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLS 334
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + Y P+ W APE L KF SDVW+FGV L+E+ T+ S
Sbjct 335 RLMT--GDTYTAHAGTKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMS----- 387
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + ++ ELLE+ R+ RP+ CP +VY LM+ CW+ S RP F +
Sbjct 388 ---------PYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPAFAEI 438
>sp|P00526|SRC_RSVP Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus subgroup C (strain Prague) OX=11888
GN=V-SRC PE=1 SV=3
Length=526
Score = 299 bits (765), Expect = 2e-88, Method: Composition-based stats.
Identities = 95/437 (22%), Positives = 161/437 (37%), Gaps = 71/437 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L+V+
Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRKSETAKGAYCLSVSD----F 191
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + ++ + I + F S+++L A A C L C
Sbjct 192 DNAKGPNVKHYKIYKLYSGGFYITSRTQFGSLQQLVAYYSKH---ADGLCHRLANVCP-- 246
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ P+T L++ + ++ + + LGQG V+ G
Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEAKLGQGCFGEVWMGTWNDT--- 289
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
RV +K L P AF + A +M ++ H L ++
Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 326
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +V EY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH
Sbjct 327 AVVSE-EPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 496
Query 847 QCLTYEPTQRPSFRTIL 863
QC +P +RP+F+ +
Sbjct 497 QCWRKDPEERPTFKYLQ 513
Score = 283 bits (724), Expect = 1e-82, Method: Composition-based stats.
Identities = 93/305 (30%), Positives = 143/305 (47%), Gaps = 29/305 (10%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ N+ A D + L+ LG+G FG+V + ++ T V
Sbjct 238 CHRLANVCPTSKPQTQGLAKDAWEIPRESLRLEAKLGQGCFGEVWMGTWNDTTR-----V 292
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL
Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVIEYMSKGSLL 347
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ERG R+P P +CP ++ LM CW + RPTF+
Sbjct 461 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFKY 511
Query 1165 LIPIL 1169
L L
Sbjct 512 LQAQL 516
>sp|P25020|SRC_RSVH1 Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus (strain H-19) OX=11887 GN=V-SRC
PE=1 SV=3
Length=526
Score = 298 bits (764), Expect = 3e-88, Method: Composition-based stats.
Identities = 95/437 (22%), Positives = 161/437 (37%), Gaps = 71/437 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G +L+ S + L+V+
Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRKSETAKGAYCLSVSD----F 191
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + ++ + I + F S+++L A A C L C
Sbjct 192 DNAKGPNVKHYKICKLYSGGFYITSRTQFGSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ P+T L++ + ++ + + LGQG V+ G
Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEAKLGQGCFGEVWMGTWNGT--- 289
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
RV +K L P AF + A +M ++ H L ++
Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 326
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +V EY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH
Sbjct 327 AVVSE-EPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG L E+ G P E +R +R+P P CP+ L L
Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERAYRMPCPPECPESLHDLMC 496
Query 847 QCLTYEPTQRPSFRTIL 863
QC +P +RP+F+ +
Sbjct 497 QCWRKDPEERPTFKYLQ 513
Score = 282 bits (722), Expect = 2e-82, Method: Composition-based stats.
Identities = 92/305 (30%), Positives = 142/305 (47%), Gaps = 29/305 (10%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ N+ A D + L+ LG+G FG+V + ++ T V
Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEAKLGQGCFGEVWMGTWNGTTR-----V 292
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL
Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVIEYMSKGSLL 347
Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL
Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T
Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + + +ER R+P P +CP ++ LM CW + RPTF+
Sbjct 461 ---------VPYPGMVNREVLDQVERAYRMPCPPECPESLHDLMCQCWRKDPEERPTFKY 511
Query 1165 LIPIL 1169
L L
Sbjct 512 LQAQL 516
>sp|P16591|FER_HUMAN Tyrosine-protein kinase Fer OS=Homo sapiens
OX=9606 GN=FER PE=1 SV=2
Length=822
Score = 306 bits (785), Expect = 4e-88, Method: Composition-based stats.
Identities = 91/433 (21%), Positives = 178/433 (41%), Gaps = 80/433 (18%)
Query 447 IRDGIHGPLLEPFVQAK-LRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKF 505
+D HG + P ++A+ L + G +L+ S P +L+V DG + R F
Sbjct 457 EQDWYHGAI--PRIEAQELLKKQGDFLVRESHGKPGEYVLSVY-----SDGQR----RHF 505
Query 506 PIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMR 565
I+ D + EG G F ++ +L D ++ ++ + S ++++
Sbjct 506 IIQYVDNMYRFEGTG--FSNIPQLI-----------DHHYTTKQVITKK----SGVVLLN 548
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
+ + + +++ LG+G VY+G L+
Sbjct 549 P---------IPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKD--------------- 584
Query 626 PLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+ V +K ++ + F + A ++ Q H ++ + GVC +
Sbjct 585 ----------KTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVY 634
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
++ E V G +LRR++ + + + + A+ + YLE+KN +H ++ RN L+
Sbjct 635 IIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLESKNCIHRDLAARNCLV-- 692
Query 745 LGLAEGTSPFIKLSDPGVGL---GALSREERVERIP--WLAPECLPGGANSLSTAMDKWG 799
G + +K+SD G+ G + +++IP W APE L G S+ D W
Sbjct 693 -----GENNVLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYG--RYSSESDVWS 745
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857
FG L E G P + + +R +R+ P+ ++ + +C Y+P RP
Sbjct 746 FGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRP 805
Query 858 SFRTILRDLTRLQ 870
F + ++LT ++
Sbjct 806 KFSELQKELTIIK 818
Score = 274 bits (700), Expect = 1e-76, Method: Composition-based stats.
Identities = 91/317 (29%), Positives = 138/317 (44%), Gaps = 25/317 (8%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
I T Q + + P + + LG+G+FG+V
Sbjct 528 IDHHYTTKQVITKKSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLK---- 583
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VAVK K D + + + QE IL+ H +I+K G C + + + ++ME V
Sbjct 584 -DKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQR--QPVYIIMELV 640
Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
G +L R + L QL+ F+ GM YL +++ IHRDLAARN L+ + ++KI
Sbjct 641 SGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKI 700
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFG+++ E Y P+ W APE L ++ SDVWSFG+ L+E +
Sbjct 701 SDFGMSRQ--EDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFS--- 755
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L MT + E +ERG R+ P CP ++ +M CW+ + R
Sbjct 756 -----------LGVCPYPGMTNQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENR 804
Query 1160 PTFENLIPILKTVHEKY 1176
P F L L + K
Sbjct 805 PKFSELQKELTIIKRKL 821
>sp|Q28923|YES_CANLF Tyrosine-protein kinase Yes OS=Canis lupus
familiaris OX=9615 GN=YES1 PE=1 SV=3
Length=539
Score = 298 bits (763), Expect = 6e-88, Method: Composition-based stats.
Identities = 88/453 (19%), Positives = 158/453 (35%), Gaps = 71/453 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + L + G++L+ S + L++
Sbjct 143 VAPADSIAA-EEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDW---- 197
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D ++ ++ + I + D F ++++L A C L C
Sbjct 198 DEIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKH---STEHADGLCHKLTTVCP-- 252
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P+T L++ + ++ + LGQG V+ G
Sbjct 253 -------------TVKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 295
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L + AF + A +M ++ H L ++
Sbjct 296 ----------------------TKVAIKTLKLGTM-MPEAFLQEAQIMKKLRHDKLVPLY 332
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTE++ G L +L+ G + + + +A Q+A ++Y+E N +H
Sbjct 333 AVVSE-EPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHR 391
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788
++ NIL+ G + K++D G+ E I W APE G
Sbjct 392 DLRAANILV-------GENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 443
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846
+ D W FG E+ G P E +R +R+P P CP+ L L +
Sbjct 444 -RFTIKSDVWSFGILQTELTTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMN 502
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
C +P +RP+F I L
Sbjct 503 LCWKKDPDERPTFEYIQSFLEDYFTAAEPQYQP 535
Score = 287 bits (734), Expect = 7e-84, Method: Composition-based stats.
Identities = 94/315 (30%), Positives = 144/315 (46%), Gaps = 29/315 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
+ + + A D + L+ LG+G FG+V + ++ T V
Sbjct 244 CHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT-----TKV 298
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL
Sbjct 299 AIKTLKL--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEFMSKGSLL 353
Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
D+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ + + KI DFGL
Sbjct 354 DFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGL 413
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + + Y R+ P+ W APE +F SDVWSFG+ EL T
Sbjct 414 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELTTKGR----- 466
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ M + E +ERG R+P P CP ++ LM CW+ + RPTFE
Sbjct 467 ---------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEY 517
Query 1165 LIPILKTVHEKYQGQ 1179
+ L+ + Q
Sbjct 518 IQSFLEDYFTAAEPQ 532
>sp|O13148|EPA4A_DANRE Ephrin type-A receptor 4a (Fragment) OS=Danio
rerio OX=7955 GN=epha4a PE=2 SV=1
Length=292
Score = 288 bits (737), Expect = 1e-87, Method: Composition-based stats.
Identities = 85/282 (30%), Positives = 143/282 (51%), Gaps = 30/282 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG+V G E+ VA+K LKA + R + E I+ H +II+
Sbjct 1 IGIGEFGEVCSGRLKM--PGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIR 58
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHY 1019
+G K + ++ EY+ GSL +L ++ + QL+ + I GM YL Y
Sbjct 59 LEGVVTKC--KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGILRGIASGMKYLSDMSY 116
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE-YYRVREDGDS--------PVFWYAP 1070
+HRDLAARN+L++++ + K+ DFG+++ + E + Y RE + P+ W AP
Sbjct 117 VHRDLAARNILVNSNLVCKVSDFGMSRVLEEDPDAAYTTREITGTYQSQGGKIPIRWTAP 176
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E + KF ASDVWS+G+ ++E++++ + M+ + + +E
Sbjct 177 EAITYRKFTSASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVIKAIEE 222
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
G RLP P CP ++ LM +CW+ E + RP F ++ +L +
Sbjct 223 GYRLPPPMDCPVSLHQLMLDCWQKERAERPKFSQIVNMLDKL 264
Score = 266 bits (680), Expect = 1e-79, Method: Composition-based stats.
Identities = 76/298 (26%), Positives = 124/298 (42%), Gaps = 49/298 (16%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653
+G G V GRL++ G +E+ V +K L + D
Sbjct 1 IGIGEFGEVCSGRLKMPGK---------------------REICVAIKTLKAGYTDKQRR 39
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
F AS+M Q H ++ + GV + +++TEY+E+G LD +LR+ G + +
Sbjct 40 DFLSEASIMGQFDHPNIIRLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVG 99
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-------GA 766
+ + +AS + YL + + VH ++ RNIL+ ++ K+SD G+ A
Sbjct 100 ILRGIASGMKYLSDMSYVHRDLAARNILVN-------SNLVCKVSDFGMSRVLEEDPDAA 152
Query 767 LSREERVER---------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ E I W APE + ++A D W +G + E+ GE P
Sbjct 153 YTTREITGTYQSQGGKIPIRWTAPEAIT--YRKFTSASDVWSYGIVMWEVMSYGERPYWD 210
Query 818 RSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
S + + +RLP P CP L L C E +RP F I+ L +L +
Sbjct 211 MSNQDVIKAIEEGYRLPPPMDCPVSLHQLMLDCWQKERAERPKFSQIVNMLDKLIRNP 268
>sp|G5EE56|SRC1_CAEEL Tyrosine protein-kinase src-1 OS=Caenorhabditis
elegans OX=6239 GN=src-1 PE=1 SV=1
Length=533
Score = 297 bits (760), Expect = 1e-87, Method: Composition-based stats.
Identities = 92/457 (20%), Positives = 166/457 (36%), Gaps = 66/457 (14%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494
VA + + S + G + + + G +LI + LT+
Sbjct 127 VAKQQTIES-EEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQR 185
Query 495 DG--MQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552
+G ++ ++++ D + + R+F S++EL C L
Sbjct 186 NGGTVKHYKIKRL---DHDQGYFIT-TRRTFRSLQELVRYYSD---VPDGLCCQLTFPAP 238
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
R A P L+ + + ++ LG G V+ G+ R
Sbjct 239 ------------RLAPTRP-DLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGI- 284
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672
+ V +K + P AF + A +M Q H +L
Sbjct 285 ------------------------VEVAIKTMKPGTMSP-EAFLQEAQIMKQCDHPNLVK 319
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVH 732
++ VC R ++TEY+ +G L +LR + + + + +A Q+A+ + YLE + LVH
Sbjct 320 LYAVCTREEPFYIITEYMINGSLLQYLRTDGSTLGIQALVDMAAQIANGMMYLEERKLVH 379
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL------SREERVERIPWLAPECLPG 786
++ RN+L+ G P +K++D G+ + +R I W APE
Sbjct 380 RDLAARNVLV---GDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATC 436
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ--LAT 843
G + + D W +G L EI G+ P E + +R+P P CP+
Sbjct 437 G--NFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEE 494
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880
+ +C P +RP+F T+ +
Sbjct 495 VLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQPNYAPP 531
Score = 270 bits (689), Expect = 9e-78, Method: Composition-based stats.
Identities = 90/314 (29%), Positives = 136/314 (43%), Gaps = 31/314 (10%)
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
P + + L R LG+G+FG+V +
Sbjct 230 CCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGI----- 284
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
VA+K +K G + QE I++ H +++K C E+ ++ EY+ G
Sbjct 285 VEVAIKTMKP--GTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTR--EEPFYIITEYMING 340
Query 985 SLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND----RLVK 1038
SL YL ++G+ L+ A QI GM YL + +HRDLAARNVL+ + +VK
Sbjct 341 SLLQYLRTDGSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVK 400
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
+ DFGLA+ + E + Y R P+ W APE F SDVWS+G+ LYE++T
Sbjct 401 VADFGLARKLME-EDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKG 459
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY-HLMKNCWETEAS 1157
+ M + E +E G R+P P CP ++Y ++ CW+
Sbjct 460 Q--------------VPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPD 505
Query 1158 FRPTFENLIPILKT 1171
RPTF+ L
Sbjct 506 RRPTFDTLYHFFDD 519
>sp|P00521|ABL_MLVAB Tyrosine-protein kinase transforming protein
Abl OS=Abelson murine leukemia virus OX=11788 GN=ABL PE=3
SV=1
Length=746
Score = 303 bits (775), Expect = 2e-87, Method: Composition-based stats.
Identities = 96/436 (22%), Positives = 159/436 (36%), Gaps = 70/436 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
HGP+ + L +G +L+ S S P + +++ R+
Sbjct 9 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG---------RVYH 59
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ I + F ++ EL A +L
Sbjct 60 YRINTASDGKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPK----------- 105
Query 565 RGARASPRTLNLSQ-LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
R P +S +++ +IT LG G VYEG +
Sbjct 106 ---RNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYS----------- 151
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
L V +K L ++ F + A++M ++ H +L + GVC R P
Sbjct 152 -------------LTVAVKTLKEDTMEV-EEFLKEAAVMKEIKHPNLVQLLGVCTREPPF 197
Query 684 IMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
++TE++ +G L +LR R V + +A Q++SA+ YLE KN +H ++ RN L+
Sbjct 198 YIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV 257
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDK 797
G + +K++D G+ I W APE L N S D
Sbjct 258 -------GENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLA--YNKFSIKSDV 308
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855
W FG L EI G +P S+ ++ +R+ PE ++ L C + P+
Sbjct 309 WAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSD 368
Query 856 RPSFRTILRDLTRLQP 871
RPSF I + +
Sbjct 369 RPSFAEIHQAFETMFQ 384
Score = 295 bits (755), Expect = 1e-84, Method: Composition-based stats.
Identities = 94/310 (30%), Positives = 149/310 (48%), Gaps = 27/310 (9%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
P + T+ SP D + + LG G +G+V + + VA
Sbjct 100 HYPAPKRNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSL----TVA 155
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
VK LK D + +E +++ + H ++++ G C E ++ E++ G+L D
Sbjct 156 VKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLD 211
Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
YL R + LL A QI M YL +++IHRDLAARN L+ + LVK+ DFGL+
Sbjct 212 YLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLS 271
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + Y P+ W APE L KF SDVW+FGV L+E+ T+ S
Sbjct 272 RLMT--GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMS----- 324
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + ++ ELLE+ R+ RP+ CP +VY LM+ CW+ S RP+F +
Sbjct 325 ---------PYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 375
Query 1166 IPILKTVHEK 1175
+T+ ++
Sbjct 376 HQAFETMFQE 385
>sp|P09769|FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo sapiens
OX=9606 GN=FGR PE=1 SV=2
Length=529
Score = 294 bits (752), Expect = 2e-86, Method: Composition-based stats.
Identities = 94/456 (21%), Positives = 156/456 (34%), Gaps = 71/456 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + +L G +LI S + L++
Sbjct 133 VAPVDSIQA-EEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDW---- 187
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + ++ + I + D F SV+EL C
Sbjct 188 DQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVN---DGLC---------- 234
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
NL+I P+TL L++ + + IT LG G +V+ G
Sbjct 235 -----NLLIAPCTIMKPQTLGLAK-DAWEISRSSITLERRLGTGCFGDVWLGTWNGS--- 285
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P AF E A +M + H L ++
Sbjct 286 ----------------------TKVAVKTLKPGTMSP-KAFLEEAQVMKLLRHDKLVQLY 322
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTE++ HG L +L+ G + + + +A Q+A ++Y+E N +H
Sbjct 323 AVVSE-EPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHR 381
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGGA 788
++ NIL+ G K++D G+ E I W APE G
Sbjct 382 DLRAANILV-------GERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFG- 433
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846
+ D W FG L E+ G P + E ++ + +P P CP L
Sbjct 434 -RFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAME 492
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
Q +P +RP+F + L +
Sbjct 493 QTWRLDPEERPTFEYLQSFLEDYFTSAEPQYQPGDQ 528
Score = 270 bits (689), Expect = 8e-78, Method: Composition-based stats.
Identities = 92/309 (30%), Positives = 138/309 (45%), Gaps = 29/309 (9%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933
++ A D + + R LG G FG V L ++ + VAVK LK
Sbjct 240 PCTIMKPQTLGLAKDAWEISRSSITLERRLGTGCFGDVWLGTWNGS-----TKVAVKTLK 294
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR- 992
G + +E +++ L H+ +++ E+ + +V E++ GSL D+L
Sbjct 295 P--GTMSPKAFLEEAQVMKLLRHDKLVQLYAVV---SEEPIYIVTEFMCHGSLLDFLKNP 349
Query 993 --HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
+ L QL+ A Q+ EGMAY+ +YIHRDL A N+L+ KI DFGLA+ + +
Sbjct 350 EGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARLIKD 409
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
Y + P+ W APE +F SDVWSFG+ L EL+T
Sbjct 410 DE--YNPCQGSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGR----------- 456
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
I M + E +E+G +P P CP +Y M+ W + RPTFE L L+
Sbjct 457 ---IPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYLQSFLE 513
Query 1171 TVHEKYQGQ 1179
+ Q
Sbjct 514 DYFTSAEPQ 522
>sp|P54755|EPHA5_CHICK Ephrin type-A receptor 5 OS=Gallus gallus
OX=9031 GN=EPHA5 PE=2 SV=1
Length=1013
Score = 305 bits (781), Expect = 4e-86, Method: Composition-based stats.
Identities = 88/337 (26%), Positives = 154/337 (46%), Gaps = 24/337 (7%)
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR-----YL 897
+L +C + Q P + ++ + + + + + +
Sbjct 592 SLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCI 651
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
R +G G FG+V VA+K LK + R + E I+ H
Sbjct 652 TIERVIGAGEFGEVCSGRLKLQGKREF-PVAIKTLKVGYTEKQRRDFLGEASIMGQFDHP 710
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015
+II +G K + +V EY+ GSL +L ++ + QL+ + I GM YL
Sbjct 711 NIIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIASGMKYLS 768
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W APE +
Sbjct 769 DMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAF 828
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF ASDVWS+G+ ++E++++ + +MT + + +E G RLP
Sbjct 829 RKFTSASDVWSYGIVMWEVMSYGER--------------PYWEMTNQDVIKAVEEGYRLP 874
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P CP +Y LM +CW+ + + RP F+ ++ +L +
Sbjct 875 SPMDCPAALYQLMLDCWQKDRNSRPKFDEIVSMLDKL 911
Score = 274 bits (701), Expect = 1e-75, Method: Composition-based stats.
Identities = 73/302 (24%), Positives = 123/302 (41%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
++ IT +G G V GRL+++G +E V +
Sbjct 644 KEIEASCITIERVIGAGEFGEVCSGRLKLQGK---------------------REFPVAI 682
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +L+
Sbjct 683 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLK 742
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +AS + YL + VH ++ RNIL+ ++ K+SD
Sbjct 743 KNDGQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 795
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E I W APE + ++A D W +G + E+ GE
Sbjct 796 GLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--FRKFTSASDVWSYGIVMWEVMSYGER 853
Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P + + + +RLP CP L L C + RP F I+ L +L
Sbjct 854 PYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVSMLDKLIR 913
Query 872 HN 873
+
Sbjct 914 NP 915
>sp|Q60629|EPHA5_MOUSE Ephrin type-A receptor 5 OS=Mus musculus
OX=10090 GN=Epha5 PE=1 SV=2
Length=876
Score = 302 bits (774), Expect = 4e-86, Method: Composition-based stats.
Identities = 87/337 (26%), Positives = 154/337 (46%), Gaps = 24/337 (7%)
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR-----YL 897
+L +C + Q P + ++ + + + + + +
Sbjct 455 SLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCI 514
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
R +G G FG+V VA+K LK + R + E I+ H
Sbjct 515 TIERVIGAGEFGEVCSGRLKLPGKRE-LPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHP 573
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015
+II +G K + +V EY+ GSL +L ++ + QL+ + I GM YL
Sbjct 574 NIIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLS 631
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W APE +
Sbjct 632 DMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAF 691
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF +SDVWS+G+ ++E++++ + +MT + + +E G RLP
Sbjct 692 RKFTSSSDVWSYGIVMWEVVSYGER--------------PYWEMTNQDVIKAVEEGYRLP 737
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P CP +Y LM +CW+ + + RP F+ ++ +L +
Sbjct 738 SPMDCPAALYQLMLDCWQKDRNSRPKFDEIVNMLDKL 774
Score = 273 bits (698), Expect = 6e-76, Method: Composition-based stats.
Identities = 72/302 (24%), Positives = 123/302 (41%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
++ IT +G G V GRL++ G +EL V +
Sbjct 507 KEIEASCITIERVIGAGEFGEVCSGRLKLPGK---------------------RELPVAI 545
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +L+
Sbjct 546 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLK 605
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL + VH ++ RNIL+ ++ K+SD
Sbjct 606 KNDGQFTVIQLVGMLRGIAAGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 658
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E I W APE + +++ D W +G + E+ GE
Sbjct 659 GLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--FRKFTSSSDVWSYGIVMWEVVSYGER 716
Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P + + + +RLP CP L L C + RP F I+ L +L
Sbjct 717 PYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVNMLDKLIR 776
Query 872 HN 873
+
Sbjct 777 NP 778
>sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens
OX=9606 GN=LYN PE=1 SV=3
Length=512
Score = 292 bits (747), Expect = 5e-86, Method: Composition-based stats.
Identities = 85/447 (19%), Positives = 152/447 (34%), Gaps = 70/447 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502
+ + + +L G +LI S + L+V + +
Sbjct 125 ETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDP----VHGDVI 180
Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562
+ + I D +FP + ++ Q A C L + C+
Sbjct 181 KHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQ---ADGLCRRLEKACI---------- 227
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
SP+ + ++ I + LG G V+ G
Sbjct 228 -------SPKPQKPWDKDAWEIPRESIKLVKRLGAGQFGEVWMG---------------- 264
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
+V +K L P + AF E A+LM + H L ++ V R
Sbjct 265 ---------YYNNSTKVAVKTLKPGTMSVQ-AFLEEANLMKTLQHDKLVRLYAVVTREEP 314
Query 683 NIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
++TEY+ G L +L+ + G V + + + Q+A ++Y+E KN +H ++ N+L
Sbjct 315 IYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVL 374
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMD 796
++ S K++D G+ E I W APE + G + D
Sbjct 375 VSE-------SLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGC--FTIKSD 425
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP--EPSCPQLATLTSQCLTYEPT 854
W FG L EI G+ P R+ ++ + +R+P E +L + C +
Sbjct 426 VWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKMCWKEKAE 485
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVN 881
+RP+F + L
Sbjct 486 ERPTFDYLQSVLDDFYTATEGQYQQQP 512
Score = 279 bits (714), Expect = 2e-81, Method: Composition-based stats.
Identities = 101/293 (34%), Positives = 153/293 (52%), Gaps = 28/293 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ +K ++ LG G FG+V + Y N+ T VAVK LK G + +E +
Sbjct 240 WEIPRESIKLVKRLGAGQFGEVWMGYY---NNST--KVAVKTLKP--GTMSVQAFLEEAN 292
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQ 1006
+++TL H+ +++ E+ + ++ EY+ GSL D+L G L +L+ F+ Q
Sbjct 293 LMKTLQHDKLVRLYAVVTR--EEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQ 350
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I EGMAY+ ++YIHRDL A NVL+ + KI DFGLA+ + + Y RE P+
Sbjct 351 IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIK 408
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE + F SDVWSFG+ LYE++T+ I T +
Sbjct 409 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGK--------------IPYPGRTNADVMT 454
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +G R+PR + CP E+Y +MK CW+ +A RPTF+ L +L + +GQ
Sbjct 455 ALSQGYRMPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQ 507
>sp|P25911|LYN_MOUSE Tyrosine-protein kinase Lyn OS=Mus musculus
OX=10090 GN=Lyn PE=1 SV=4
Length=512
Score = 292 bits (747), Expect = 5e-86, Method: Composition-based stats.
Identities = 84/447 (19%), Positives = 153/447 (34%), Gaps = 70/447 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502
+ + + +L G +LI S + L+V M +
Sbjct 125 ETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDP----MHGDVI 180
Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562
+ + I D +FP + ++ Q + C L + C+
Sbjct 181 KHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQ---SDGLCRRLEKACI---------- 227
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
SP+ + ++ I + LG G V+ G
Sbjct 228 -------SPKPQKPWDKDAWEIPRESIKLVKKLGAGQFGEVWMG---------------- 264
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
+V +K L P + AF E A+LM + H L ++ V +
Sbjct 265 ---------YYNNSTKVAVKTLKPGTMSVQ-AFLEEANLMKTLQHDKLVRLYAVVTKEEP 314
Query 683 NIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
++TE++ G L +L+ + G V + + + Q+A ++Y+E KN +H ++ N+L
Sbjct 315 IYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVL 374
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMD 796
++ S K++D G+ E I W APE + G + D
Sbjct 375 VSE-------SLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGC--FTIKSD 425
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPT 854
W FG L EI G+ P R+ ++ + +R+P +CP L + C +
Sbjct 426 VWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPRMENCPDELYDIMKMCWKEKAE 485
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVN 881
+RP+F + L
Sbjct 486 ERPTFDYLQSVLDDFYTATEGQYQQQP 512
Score = 278 bits (711), Expect = 5e-81, Method: Composition-based stats.
Identities = 100/293 (34%), Positives = 153/293 (52%), Gaps = 28/293 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ +K ++ LG G FG+V + Y N+ T VAVK LK G + +E +
Sbjct 240 WEIPRESIKLVKKLGAGQFGEVWMGYY---NNST--KVAVKTLKP--GTMSVQAFLEEAN 292
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQ 1006
+++TL H+ +++ E+ + ++ E++ GSL D+L G L +L+ F+ Q
Sbjct 293 LMKTLQHDKLVRLYAVVTK--EEPIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQ 350
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I EGMAY+ ++YIHRDL A NVL+ + KI DFGLA+ + + Y RE P+
Sbjct 351 IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIK 408
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE + F SDVWSFG+ LYE++T+ I T +
Sbjct 409 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGK--------------IPYPGRTNADVMS 454
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +G R+PR + CP E+Y +MK CW+ +A RPTF+ L +L + +GQ
Sbjct 455 ALSQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQ 507
>sp|P00543|FES_FSVST Tyrosine-protein kinase transforming protein
Fes OS=Feline sarcoma virus (strain Snyder-Theilen) OX=11780
GN=V-FES PE=3 SV=1
Length=477
Score = 290 bits (743), Expect = 6e-86, Method: Composition-based stats.
Identities = 112/451 (25%), Positives = 176/451 (39%), Gaps = 85/451 (19%)
Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQ-AKLRPEDGLYLIHWSTSHPYRLILTVAQRSQ 492
L EV P + HG L P + A+L G +L+ S +L+V
Sbjct 102 LVPEVQKPL---HEQLWYHGAL--PRAEVAELLTHSGDFLVRESQGKQ-EYVLSV----- 150
Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552
DG R F I+ D + EG G F S+ L L LR+
Sbjct 151 LWDGQP----RHFIIQSADNLYRPEGDG--FASIPLLVDHL----LRS------------ 188
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
QP + I++ A + ++ +++ +G+G V+ GRLR +
Sbjct 189 QQPLTKKSGIVLNRAVPKDK---------WVLNHEDLVLGEQIGRGNFGEVFSGRLRADN 239
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLA 671
V +K + DI F + A ++ Q SH ++
Sbjct 240 ------------------------TLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIV 275
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
+ GVC + +V E V+ G +LR E + M + + A+ + YLE+K +
Sbjct 276 RLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCI 335
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPECLP 785
H ++ RN L+ + +K+SD G+ A S R+ + W APE L
Sbjct 336 HRDLAARNCLVTEKNV-------LKISDFGMSREEADGVYAASGGLRLVPVKWTAPEALN 388
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LAT 843
G S+ D W FG L E G +P + S + F ++ RLP P CP +
Sbjct 389 YG--RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFR 446
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
L QC YEP QRPSF ++L ++ +
Sbjct 447 LMEQCWAYEPGQRPSFSAFYQELQSIRKRHR 477
Score = 270 bits (689), Expect = 2e-78, Method: Composition-based stats.
Identities = 87/294 (30%), Positives = 138/294 (47%), Gaps = 23/294 (8%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
D V + L +G G+FG+V N +VAVK+ + P ++ +
Sbjct 205 PKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADN----TLVAVKSCRETLPPDIKAKFL 260
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLF 1003
QE IL+ H +I++ G C + + + +VME V G +L + + LL
Sbjct 261 QEAKILKQYSHPNIVRLIGVCTQK--QPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQM 318
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
GM YL ++ IHRDLAARN L+ ++KI DFG+++ +G Y
Sbjct 319 VGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGV-YAASGGLRLV 377
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
PV W APE L ++ SDVWSFG+ L+E + L ++ +
Sbjct 378 PVKWTAPEALNYGRYSSESDVWSFGILLWETFS--------------LGASPYPNLSNQQ 423
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
E +E+G RLP P+ CP V+ LM+ CW E RP+F L+++ ++++
Sbjct 424 TREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAFYQELQSIRKRHR 477
>sp|Q07014|LYN_RAT Tyrosine-protein kinase Lyn OS=Rattus norvegicus
OX=10116 GN=Lyn PE=1 SV=3
Length=512
Score = 291 bits (746), Expect = 7e-86, Method: Composition-based stats.
Identities = 85/447 (19%), Positives = 152/447 (34%), Gaps = 70/447 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502
+ + + +L G +LI S + L+V M +
Sbjct 125 ETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDP----MHGDVI 180
Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562
+ + I D +FP + ++ Q + C L + C+
Sbjct 181 KHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQ---SDGLCRRLEKACI---------- 227
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
SP+ + ++ I + LG G V+ G
Sbjct 228 -------SPKPQKPWDKDAWEIPRESIKLVKKLGAGQFGEVWMG---------------- 264
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
+V +K L P A AF E A+LM + H L ++ V +
Sbjct 265 ---------YYNNSTKVAVKTLKPGTMS-AQAFLEEANLMKTLQHDKLVRLYAVVTKEEP 314
Query 683 NIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
++TE++ G L +L+ + G V + + + Q+A ++Y+E KN +H ++ N+L
Sbjct 315 IYIITEFMAKGSLLDFLKSDEGSKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVL 374
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMD 796
++ S K++D G+ E I W APE + G + D
Sbjct 375 VSE-------SLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGC--FTIKSD 425
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPT 854
W FG L EI G+ P R+ ++ + +R+P +CP L + C
Sbjct 426 VWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRMENCPDELYDIMKMCWKESAE 485
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVN 881
+RP+F + L
Sbjct 486 ERPTFDYLQSVLDDFYTATEGQYQQQP 512
Score = 277 bits (708), Expect = 1e-80, Method: Composition-based stats.
Identities = 99/293 (34%), Positives = 151/293 (52%), Gaps = 28/293 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ +K ++ LG G FG+V + Y N+ T VAVK LK G + +E +
Sbjct 240 WEIPRESIKLVKKLGAGQFGEVWMGYY---NNST--KVAVKTLKP--GTMSAQAFLEEAN 292
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQ 1006
+++TL H+ +++ E+ + ++ E++ GSL D+L L +L+ F+ Q
Sbjct 293 LMKTLQHDKLVRLYAVVTK--EEPIYIITEFMAKGSLLDFLKSDEGSKVLLPKLIDFSAQ 350
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I EGMAY+ ++YIHRDL A NVL+ + KI DFGLA+ + + Y RE P+
Sbjct 351 IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIK 408
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE + F SDVWSFG+ LYE++T+ I T +
Sbjct 409 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGK--------------IPYPGRTNADVMT 454
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +G R+PR + CP E+Y +MK CW+ A RPTF+ L +L + +GQ
Sbjct 455 ALSQGYRMPRMENCPDELYDIMKMCWKESAEERPTFDYLQSVLDDFYTATEGQ 507
>sp|Q95KR7|LCK_SAISC Proto-oncogene tyrosine-protein kinase LCK
OS=Saimiri sciureus OX=9521 GN=LCK PE=1 SV=3
Length=509
Score = 291 bits (744), Expect = 1e-85, Method: Composition-based stats.
Identities = 103/293 (35%), Positives = 150/293 (51%), Gaps = 29/293 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ LK + LG G FG+V + Y N+ T VAVK+LK G + E +
Sbjct 238 WEVPRETLKLVERLGAGQFGEVWMGYY---NEHT--KVAVKSLKQ--GSMSPDAFLAEAN 290
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQ 1006
+++ L H+ +++ E+ + ++ EY+ GSL D+L S + + +LL A Q
Sbjct 291 LMKQLQHKRLVRLYAVV---TEEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQ 347
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I EGMA+L ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+
Sbjct 348 IVEGMAFLEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIK 405
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE + F SDVWSFG+ + E++TH I MT + +
Sbjct 406 WTAPEAINYGTFTIKSDVWSFGILMTEIVTHGR--------------IPYPGMTNPEVIQ 451
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
LERG R+PRPD CP E+Y LM CW RPTF+ L +L+ +GQ
Sbjct 452 NLERGYRMPRPDNCPEELYKLMMQCWRERPDDRPTFDYLRSVLEDFFTATEGQ 504
Score = 288 bits (737), Expect = 1e-84, Method: Composition-based stats.
Identities = 85/404 (21%), Positives = 142/404 (35%), Gaps = 68/404 (17%)
Query 468 DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVR 527
G +LI S S L+V Q Q ++ + I D +F +
Sbjct 148 HGSFLIRESESTAGSFSLSVRDFDQN----QGEVVKHYKIRNLDNGGFYISPRITFSGLH 203
Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587
EL + C L R C Q P+ V ++
Sbjct 204 ELVRHYTNA---SDGLCTRLSRPCQTQ---------------KPQKPWWE--DEWEVPRE 243
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ + LG G V+ G + +V +K L
Sbjct 244 TLKLVERLGAGQFGEVWMG-------------------------YYNEHTKVAVKSLKQG 278
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HV 706
AF A+LM Q+ H L ++ V ++TEY+E+G L +L+ G +
Sbjct 279 SMSP-DAFLAEANLMKQLQHKRLVRLYAVVTE-EPIYIITEYMENGSLVDFLKTPSGIKL 336
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ + +A Q+ +++LE +N +H ++ NIL++ + K++D G+
Sbjct 337 TINKLLDMAAQIVEGMAFLEERNYIHRDLRAANILVS-------DTLSCKIADFGLARLI 389
Query 767 LSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
E I W APE + G + + D W FG + EI G P +
Sbjct 390 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILMTEIVTHGRIPYPGMTNP 447
Query 822 EKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
E +R +R+ P+ +L L QC P RP+F +
Sbjct 448 EVIQNLERGYRMPRPDNCPEELYKLMMQCWRERPDDRPTFDYLR 491
>sp|P42683|LCK_CHICK Proto-oncogene tyrosine-protein kinase LCK
OS=Gallus gallus OX=9031 GN=LCK PE=2 SV=2
Length=508
Score = 291 bits (744), Expect = 1e-85, Method: Composition-based stats.
Identities = 91/414 (22%), Positives = 153/414 (37%), Gaps = 71/414 (17%)
Query 460 VQAKLRPE---DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVL 516
+A+L G +LI S + L+V Q Q ++ + I D
Sbjct 136 AEARLLASGNTHGSFLIRESETSKGSYSLSVRDFDQN----QGETVKHYKIRNMDNGGYY 191
Query 517 EGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL 576
+F S+ EL + C L + C Q P+
Sbjct 192 ISPRVTFSSLHELVEYYSSS---SDGLCTRLGKPCRTQ---------------KPQKPWW 233
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
V ++ + + LG G V+ G
Sbjct 234 Q--DEWEVPRESLKLVEKLGAGQFGEVWMG-------------------------FYNGH 266
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+V +K L + AF A+LM + H L ++ V + ++TEY+E G L
Sbjct 267 TKVAIKNLKQGSMSPS-AFLAEANLMKNLQHPRLVRLYAVVTK-EPIYIITEYMEKGSLV 324
Query 697 VWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+L+ G + + + +A Q+A ++++E KN +H ++ NIL++ +
Sbjct 325 DFLKTSEGIKLSINKLLDMAAQIAEGMAFIEAKNYIHRDLRAANILVSE-------ALCC 377
Query 756 KLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ E I W APE + G + + D W FG L EI
Sbjct 378 KIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEIVTY 435
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
G P + E +R +R+P+P +CPQ L L QC +P +RP+F +
Sbjct 436 GRIPYPGMTNPEVIQNLERGYRMPQPDNCPQELYELMMQCWKEQPEERPTFEYM 489
Score = 285 bits (730), Expect = 8e-84, Method: Composition-based stats.
Identities = 99/296 (33%), Positives = 149/296 (50%), Gaps = 29/296 (10%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
D + LK + LG G FG+V + Y+ VA+K LK G S +
Sbjct 234 QDEWEVPRESLKLVEKLGAGQFGEVWMGFYNGH-----TKVAIKNLKQ--GSMSPSAFLA 286
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLF 1003
E ++++ L H +++ ++ + ++ EY+ GSL D+L + + +LL
Sbjct 287 EANLMKNLQHPRLVRLYAVV---TKEPIYIITEYMEKGSLVDFLKTSEGIKLSINKLLDM 343
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
A QI EGMA++ A++YIHRDL A N+L+ KI DFGLA+ + + Y RE
Sbjct 344 AAQIAEGMAFIEAKNYIHRDLRAANILVSEALCCKIADFGLARLIEDNE--YTAREGAKF 401
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
P+ W APE + F SDVWSFG+ L E++T+ I MT
Sbjct 402 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTYGR--------------IPYPGMTNPE 447
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+ + LERG R+P+PD CP E+Y LM CW+ + RPTFE + +L+ +GQ
Sbjct 448 VIQNLERGYRMPQPDNCPQELYELMMQCWKEQPEERPTFEYMKSVLEDFFTATEGQ 503
>sp|P42689|SRK3_SPOLA Tyrosine-protein kinase SRK3 (Fragment)
OS=Spongilla lacustris OX=6055 GN=SRK3 PE=2 SV=1
Length=334
Score = 283 bits (725), Expect = 3e-85, Method: Composition-based stats.
Identities = 98/319 (31%), Positives = 154/319 (48%), Gaps = 28/319 (9%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915
RL + + D + ++ R LG+G+FG+V
Sbjct 25 SHYMMDADGLAQRLSRPCSRANIPITSGLSYKDEWEIDRTTIQLQRKLGQGNFGEVWAGV 84
Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
++ T VAVK LK D + QE +++ ++H ++++ C + +
Sbjct 85 WNGT-----TAVAVKTLKPDT--MEVKDFVQEAQVMKKIHHPNLLQLYAVCTIG--EPIY 135
Query 976 LVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032
+V E + GS+ +YL +I L Q++ + QI GM YL A YIHRDLAARN+L+
Sbjct 136 IVTELMKYGSMLEYLKHGEGKNITLHQMVDMSAQIASGMTYLEAHSYIHRDLAARNILVG 195
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
+ K+ DFGLA+ + E + Y RE P+ W APE +F SDVWSFGV +
Sbjct 196 EGNVCKVADFGLARVIKE--DIYNPREGTKFPIKWTAPEAALYNRFTIKSDVWSFGVLIS 253
Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152
E++TH + MT ++ E ++RG R+P P+ CP +Y +M +CW
Sbjct 254 EIVTHGR--------------MPYPGMTNRQVLEAVDRGYRMPCPEGCPDPLYKIMLSCW 299
Query 1153 ETEASFRPTFENLIPILKT 1171
+ E RPTFE+L +L+
Sbjct 300 KHEPDDRPTFESLKNLLED 318
Score = 275 bits (702), Expect = 4e-82, Method: Composition-based stats.
Identities = 81/366 (22%), Positives = 135/366 (37%), Gaps = 60/366 (16%)
Query 507 IEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRG 566
I D SFP+++ L + ++ A L R C
Sbjct 1 IRTLDDGGFYMANRISFPTLQNLVSHY---MMDADGLAQRLSRPC--------------S 43
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
P T LS +D+ I LGQG V+ G
Sbjct 44 RANIPITSGLSYKDEWEIDRTTIQLQRKLGQGNFGEVWAGVWNGT--------------- 88
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
V +K L P ++ F + A +M ++ H +L ++ VC G +V
Sbjct 89 ----------TAVAVKTLKPDTMEV-KDFVQEAQVMKKIHHPNLLQLYAVCTIGEPIYIV 137
Query 687 TEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
TE +++G + +L+ G + + + ++ Q+AS ++YLE + +H ++ RNIL+
Sbjct 138 TELMKYGSMLEYLKHGEGKNITLHQMVDMSAQIASGMTYLEAHSYIHRDLAARNILVGEG 197
Query 746 GLAEGTSPFIKLSDPGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGF 800
+ K++D G+ RE I W APE N + D W F
Sbjct 198 NV-------CKVADFGLARVIKEDIYNPREGTKFPIKWTAPEAAL--YNRFTIKSDVWSF 248
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPS 858
G + EI G P + + R +R+P P L + C +EP RP+
Sbjct 249 GVLISEIVTHGRMPYPGMTNRQVLEAVDRGYRMPCPEGCPDPLYKIMLSCWKHEPDDRPT 308
Query 859 FRTILR 864
F ++
Sbjct 309 FESLKN 314
>sp|Q01621|LCK_RAT Proto-oncogene tyrosine-protein kinase LCK
OS=Rattus norvegicus OX=10116 GN=Lck PE=1 SV=3
Length=509
Score = 289 bits (740), Expect = 4e-85, Method: Composition-based stats.
Identities = 84/404 (21%), Positives = 143/404 (35%), Gaps = 68/404 (17%)
Query 468 DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVR 527
G +LI S S L+V Q Q ++ + I D +FP +
Sbjct 148 HGSFLIRESESTAGSFSLSVRDFDQN----QGEVVKHYKIRNLDNGGFYISPRITFPGLH 203
Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587
+L + C L R C Q P+ V ++
Sbjct 204 DLVRHYTNA---SDGLCTKLSRPCQTQ---------------KPQKPWWE--DEWEVPRE 243
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ + LG G V+ G +V +K L
Sbjct 244 TLKLVERLGAGQFGEVWMG-------------------------YYNGHTKVAVKSLKQG 278
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HV 706
AF A+LM Q+ H L ++ V + ++TEY+E+G L +L+ G +
Sbjct 279 SMSP-DAFLAEANLMKQLQHPRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIKL 336
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ + +A Q+A ++++E +N +H ++ NIL++ + K++D G+
Sbjct 337 NVNKLLDMAAQIAEGMAFIEEQNYIHRDLRAANILVS-------DTLSCKIADFGLARLI 389
Query 767 LSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
E I W APE + G + + D W FG L EI G P +
Sbjct 390 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP 447
Query 822 EKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
E ++ +R+ P+ +L L C P RP+F +
Sbjct 448 EVIQNLEKGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLR 491
Score = 288 bits (738), Expect = 7e-85, Method: Composition-based stats.
Identities = 100/293 (34%), Positives = 147/293 (50%), Gaps = 29/293 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ LK + LG G FG+V + Y+ VAVK+LK G + E +
Sbjct 238 WEVPRETLKLVERLGAGQFGEVWMGYYNGH-----TKVAVKSLKQ--GSMSPDAFLAEAN 290
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQ 1006
+++ L H +++ ++ + ++ EY+ GSL D+L S + + +LL A Q
Sbjct 291 LMKQLQHPRLVRLYAVV---TQEPIYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQ 347
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I EGMA++ Q+YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+
Sbjct 348 IAEGMAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIK 405
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE + F SDVWSFG+ L E++TH I MT + +
Sbjct 406 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQ 451
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
LE+G R+ RPD CP E+YHLM CW+ RPTF+ L +L +GQ
Sbjct 452 NLEKGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLDDFFTATEGQ 504
>sp|P06240|LCK_MOUSE Proto-oncogene tyrosine-protein kinase LCK
OS=Mus musculus OX=10090 GN=Lck PE=1 SV=4
Length=509
Score = 289 bits (740), Expect = 4e-85, Method: Composition-based stats.
Identities = 85/404 (21%), Positives = 143/404 (35%), Gaps = 68/404 (17%)
Query 468 DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVR 527
G +LI S S L+V Q Q ++ + I D +FP +
Sbjct 148 HGSFLIRESESTAGSFSLSVRDFDQN----QGEVVKHYKIRNLDNGGFYISPRITFPGLH 203
Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587
+L + C L R C Q P+ V ++
Sbjct 204 DLVRHYTNA---SDGLCTKLSRPCQTQ---------------KPQKPWWE--DEWEVPRE 243
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ + LG G V+ G +V +K L
Sbjct 244 TLKLVERLGAGQFGEVWMG-------------------------YYNGHTKVAVKSLKQG 278
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HV 706
AF A+LM Q+ H L ++ V + ++TEY+E+G L +L+ G +
Sbjct 279 SMSP-DAFLAEANLMKQLQHPRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIKL 336
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ + +A Q+A ++++E +N +H ++ NIL++ + K++D G+
Sbjct 337 NVNKLLDMAAQIAEGMAFIEEQNYIHRDLRAANILVS-------DTLSCKIADFGLARLI 389
Query 767 LSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
E I W APE + G + + D W FG L EI G P +
Sbjct 390 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP 447
Query 822 EKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
E +R +R+ P+ +L L C P RP+F +
Sbjct 448 EVIQNLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLR 491
Score = 288 bits (738), Expect = 8e-85, Method: Composition-based stats.
Identities = 101/293 (34%), Positives = 147/293 (50%), Gaps = 29/293 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ LK + LG G FG+V + Y+ VAVK+LK G + E +
Sbjct 238 WEVPRETLKLVERLGAGQFGEVWMGYYNGH-----TKVAVKSLKQ--GSMSPDAFLAEAN 290
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQ 1006
+++ L H +++ ++ + ++ EY+ GSL D+L S + + +LL A Q
Sbjct 291 LMKQLQHPRLVRLYAVV---TQEPIYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQ 347
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I EGMA++ Q+YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+
Sbjct 348 IAEGMAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIK 405
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE + F SDVWSFG+ L E++TH I MT + +
Sbjct 406 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQ 451
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
LERG R+ RPD CP E+YHLM CW+ RPTF+ L +L +GQ
Sbjct 452 NLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLDDFFTATEGQ 504
>sp|Q95M30|HCK_MACFA Tyrosine-protein kinase HCK OS=Macaca fascicularis
OX=9541 GN=HCK PE=2 SV=3
Length=504
Score = 288 bits (738), Expect = 6e-85, Method: Composition-based stats.
Identities = 81/447 (18%), Positives = 154/447 (34%), Gaps = 71/447 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502
+ + + +L G ++I S + L+V Q +
Sbjct 118 ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDP----RQGDTV 173
Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562
+ + I D +F +++EL + + C L C+
Sbjct 174 KHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKG---SDGLCQKLSVPCV---------- 220
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
S + + + ++ + LG G V+
Sbjct 221 -------SSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMAT--------------- 258
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
+ +V +K + P + AF A+LM + H L +H V +
Sbjct 259 ----------YNKHTKVAVKTMKPGSMSV-EAFLAEANLMKTLQHDKLVKLHAVVTK-EP 306
Query 683 NIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
++TE++ G L +L+ + G P+ + + Q+A ++++E +N +H ++ NIL
Sbjct 307 IYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANIL 366
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMD 796
++ S K++D G+ E I W APE + G++++ D
Sbjct 367 VS-------ASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSSTI--KSD 417
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854
W FG L+EI G P S E +R +R+ PE +L + +C P
Sbjct 418 VWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPE 477
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVN 881
+RP+F I L +
Sbjct 478 ERPTFEYIQSVLDDFYTATESQYQQQP 504
Score = 282 bits (722), Expect = 1e-82, Method: Composition-based stats.
Identities = 95/293 (32%), Positives = 147/293 (50%), Gaps = 29/293 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ LK + LG G FG+V + Y N T VAVK +K G + E +
Sbjct 233 WEIPRESLKLEKKLGAGQFGEVWMATY---NKHT--KVAVKTMKP--GSMSVEAFLAEAN 285
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQ 1006
+++TL H+ ++K ++ + ++ E++ GSL D+L L +L+ F+ Q
Sbjct 286 LMKTLQHDKLVKLHAVV---TKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ 342
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I EGMA++ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+
Sbjct 343 IAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNE--YTAREGAKFPIK 400
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE + SDVWSFG+ L E++T+ I M+ +
Sbjct 401 WTAPEAINFGSSTIKSDVWSFGILLMEIVTYGR--------------IPYPGMSNPEVIR 446
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
LERG R+PRP+ CP E+Y++M CW+ RPTFE + +L + + Q
Sbjct 447 ALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ 499
>sp|P00542|FES_FSVGA Tyrosine-protein kinase transforming protein
Fes OS=Feline sarcoma virus (strain Gardner-Arnstein) OX=11774
GN=V-FES PE=3 SV=1
Length=609
Score = 292 bits (747), Expect = 7e-85, Method: Composition-based stats.
Identities = 111/451 (25%), Positives = 174/451 (39%), Gaps = 85/451 (19%)
Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQ-AKLRPEDGLYLIHWSTSHPYRLILTVAQRSQ 492
L EV P + HG L P + A+L G +L+ S +L+V
Sbjct 234 LVPEVQKPL---HEQLWYHGAL--PRAEVAELLTHSGDFLVRESQGKQ-EYVLSV----- 282
Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552
DG R F I+ D + EG G F S+ L L LR+
Sbjct 283 LWDGQP----RHFIIQSADNLYRPEGDG--FASIPLLVDHL----LRS------------ 320
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
QP + I++ A + ++ +++ +G+G V+ GRLR +
Sbjct 321 QQPLTKKSGIVLNRAVPKDK---------WVLNHEDLVLGEQIGRGNFGEVFSGRLRADN 371
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLA 671
V +K + DI F + A ++ Q SH ++
Sbjct 372 ------------------------TLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIV 407
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
+ GVC + +V E V+ G +LR E + M + + A+ + YLE+K +
Sbjct 408 RLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCI 467
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLP 785
H ++ RN L+ + +K+SD G+ A + W APE L
Sbjct 468 HRDLAARNCLVTEKNV-------LKISDFGMSREAADGIYAASGGLRQVPVKWTAPEALN 520
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LAT 843
G S+ D W FG L E G +P + S + F ++ RLP P CP +
Sbjct 521 YG--RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFR 578
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
L QC YEP QRPSF I ++L ++ +
Sbjct 579 LMEQCWAYEPGQRPSFSAIYQELQSIRKRHR 609
Score = 273 bits (699), Expect = 2e-78, Method: Composition-based stats.
Identities = 87/294 (30%), Positives = 139/294 (47%), Gaps = 23/294 (8%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
D V + L +G G+FG+V N +VAVK+ + P ++ +
Sbjct 337 PKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADN----TLVAVKSCRETLPPDIKAKFL 392
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLF 1003
QE IL+ H +I++ G C + + + +VME V G +L + + LL
Sbjct 393 QEAKILKQYSHPNIVRLIGVCTQK--QPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQM 450
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
GM YL ++ IHRDLAARN L+ ++KI DFG+++ +G Y
Sbjct 451 VGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREAADGI-YAASGGLRQV 509
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
PV W APE L ++ SDVWSFG+ L+E + L ++ +
Sbjct 510 PVKWTAPEALNYGRYSSESDVWSFGILLWETFS--------------LGASPYPNLSNQQ 555
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
E +E+G RLP P+ CP V+ LM+ CW E RP+F + L+++ ++++
Sbjct 556 TREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQELQSIRKRHR 609
>sp|P29320|EPHA3_HUMAN Ephrin type-A receptor 3 OS=Homo sapiens
OX=9606 GN=EPHA3 PE=1 SV=2
Length=983
Score = 300 bits (769), Expect = 9e-85, Method: Composition-based stats.
Identities = 88/339 (26%), Positives = 155/339 (46%), Gaps = 24/339 (7%)
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR----- 895
+ L + Y+ + + L+ L + + + +
Sbjct 560 IYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDAT 619
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
+ + +G G FG+V + VA+K LK + R + E I+
Sbjct 620 NISIDKVVGAGEFGEVCSGRLKLPSKKE-ISVAIKTLKVGYTEKQRRDFLGEASIMGQFD 678
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAY 1013
H +II+ +G K + +V EY+ GSL +L +H + QL+ + I GM Y
Sbjct 679 HPNIIRLEGVVTKS--KPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKY 736
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
L Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W +PE +
Sbjct 737 LSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAI 796
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
KF ASDVWS+G+ L+E++++ + +M+ + + ++ G R
Sbjct 797 AYRKFTSASDVWSYGIVLWEVMSYGER--------------PYWEMSNQDVIKAVDEGYR 842
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
LP P CP +Y LM +CW+ + + RP FE ++ IL +
Sbjct 843 LPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKL 881
Score = 273 bits (699), Expect = 2e-75, Method: Composition-based stats.
Identities = 74/302 (25%), Positives = 121/302 (40%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D I+ +G G V GRL++ +E+ V +
Sbjct 614 KELDATNISIDKVVGAGEFGEVCSGRLKLPSK---------------------KEISVAI 652
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +LR
Sbjct 653 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLR 712
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ + + + + +AS + YL + VH ++ RNIL+ ++ K+SD
Sbjct 713 KHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 765
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E I W +PE + ++A D W +G L E+ GE
Sbjct 766 GLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIA--YRKFTSASDVWSYGIVLWEVMSYGER 823
Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + +RLP P CP L L C + RP F I+ L +L
Sbjct 824 PYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIR 883
Query 872 HN 873
+
Sbjct 884 NP 885
>sp|P00544|FGR_FSVGR Tyrosine-protein kinase transforming protein
Fgr OS=Feline sarcoma virus (strain Gardner-Rasheed) OX=11775
GN=V-FGR PE=3 SV=1
Length=545
Score = 289 bits (740), Expect = 9e-85, Method: Composition-based stats.
Identities = 88/450 (20%), Positives = 153/450 (34%), Gaps = 71/450 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + G + + +L G +L+ S + L++
Sbjct 156 VAPVDSIQA-EEWYFGKIGRKDAERQLLSPGNARGAFLVRESETTKGAYSLSIRDW---- 210
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D + ++ + I + D F SV+EL C L C
Sbjct 211 DEARGDHVKHYKIRKLDTGGYYITTRAQFNSVQELVQHYVEVN---DGLCHLLTAAC--- 264
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P+T+ L++ + + IT LG G +V+ G
Sbjct 265 ------------TTMKPQTMGLAK-DAWEISRSSITLQRRLGTGCFGDVWLGMWNGS--- 308
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+V +K L P + E A +M + H L ++
Sbjct 309 ----------------------TKVAVKTLKPGTMSPKAS-LEEAQIMKLLRHDKLVQLY 345
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733
V +VTE++ HG L +L+ + G + + + +A Q+A ++Y+E + +H
Sbjct 346 AVVPE-EPIYIVTEFMCHGSLLEFLKDQEGQDLTLPQLVDMAAQVAEGMAYMERMDYIHR 404
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGGA 788
++ NIL+ G K++D G+ E I W APE G
Sbjct 405 DLRAANILV-------GERLVCKIADFGLARLIEDNEYNPRQGAKFPIKWTAPEAALFG- 456
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846
+ D W FG L E+ G P + E + + +P P CP L
Sbjct 457 -RFTIKSDVWSFGILLTELISKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEAME 515
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
Q +P +RP+F + L +
Sbjct 516 QTWRLDPEERPTFEYLQSFLEDYFNGPQQN 545
Score = 265 bits (677), Expect = 5e-76, Method: Composition-based stats.
Identities = 90/300 (30%), Positives = 134/300 (45%), Gaps = 29/300 (10%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+ A D + + R LG G FG V L ++ + VAVK LK
Sbjct 264 CTTMKPQTMGLAKDAWEISRSSITLQRRLGTGCFGDVWLGMWNGS-----TKVAVKTLKP 318
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993
G +E I++ L H+ +++ E+ + +V E++ GSL ++L
Sbjct 319 --GTMSPKASLEEAQIMKLLRHDKLVQLYAVV---PEEPIYIVTEFMCHGSLLEFLKDQE 373
Query 994 --SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
+ L QL+ A Q+ EGMAY+ YIHRDL A N+L+ + KI DFGLA+ + +
Sbjct 374 GQDLTLPQLVDMAAQVAEGMAYMERMDYIHRDLRAANILVGERLVCKIADFGLARLIEDN 433
Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111
Y R+ P+ W APE +F SDVWSFG+ L EL++
Sbjct 434 E--YNPRQGAKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELISKGR------------ 479
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ M + E +E G +P P CP +Y M+ W + RPTFE L L+
Sbjct 480 --VPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYLQSFLED 537
>sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens
OX=9606 GN=ABL1 PE=1 SV=4
Length=1130
Score = 303 bits (775), Expect = 1e-84, Method: Composition-based stats.
Identities = 96/436 (22%), Positives = 159/436 (36%), Gaps = 70/436 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
HGP+ + L +G +L+ S S P + +++ R+
Sbjct 123 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG---------RVYH 173
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ I + F ++ EL A +L
Sbjct 174 YRINTASDGKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPK----------- 219
Query 565 RGARASPRTLNLSQ-LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
R P +S +++ +IT LG G VYEG +
Sbjct 220 ---RNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYS----------- 265
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
L V +K L ++ F + A++M ++ H +L + GVC R P
Sbjct 266 -------------LTVAVKTLKEDTMEV-EEFLKEAAVMKEIKHPNLVQLLGVCTREPPF 311
Query 684 IMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
++TE++ +G L +LR R V + +A Q++SA+ YLE KN +H ++ RN L+
Sbjct 312 YIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV 371
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDK 797
G + +K++D G+ I W APE L N S D
Sbjct 372 -------GENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLA--YNKFSIKSDV 422
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855
W FG L EI G +P S+ ++ +R+ PE ++ L C + P+
Sbjct 423 WAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSD 482
Query 856 RPSFRTILRDLTRLQP 871
RPSF I + +
Sbjct 483 RPSFAEIHQAFETMFQ 498
Score = 294 bits (753), Expect = 8e-82, Method: Composition-based stats.
Identities = 95/310 (31%), Positives = 149/310 (48%), Gaps = 27/310 (9%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
P + TV SP D + + LG G +G+V + + VA
Sbjct 214 HYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSL----TVA 269
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
VK LK D + +E +++ + H ++++ G C E ++ E++ G+L D
Sbjct 270 VKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLD 325
Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
YL R + LL A QI M YL +++IHRDLAARN L+ + LVK+ DFGL+
Sbjct 326 YLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLS 385
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + Y P+ W APE L KF SDVW+FGV L+E+ T+ S
Sbjct 386 RLMT--GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMS----- 438
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + ++ ELLE+ R+ RP+ CP +VY LM+ CW+ S RP+F +
Sbjct 439 ---------PYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
Query 1166 IPILKTVHEK 1175
+T+ ++
Sbjct 490 HQAFETMFQE 499
>sp|P00520|ABL1_MOUSE Tyrosine-protein kinase ABL1 OS=Mus musculus
OX=10090 GN=Abl1 PE=1 SV=3
Length=1123
Score = 303 bits (775), Expect = 1e-84, Method: Composition-based stats.
Identities = 96/436 (22%), Positives = 159/436 (36%), Gaps = 70/436 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
HGP+ + L +G +L+ S S P + +++ R+
Sbjct 123 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG---------RVYH 173
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ I + F ++ EL A +L
Sbjct 174 YRINTASDGKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPK----------- 219
Query 565 RGARASPRTLNLSQ-LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
R P +S +++ +IT LG G VYEG +
Sbjct 220 ---RNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYS----------- 265
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
L V +K L ++ F + A++M ++ H +L + GVC R P
Sbjct 266 -------------LTVAVKTLKEDTMEV-EEFLKEAAVMKEIKHPNLVQLLGVCTREPPF 311
Query 684 IMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
++TE++ +G L +LR R V + +A Q++SA+ YLE KN +H ++ RN L+
Sbjct 312 YIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV 371
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDK 797
G + +K++D G+ I W APE L N S D
Sbjct 372 -------GENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLA--YNKFSIKSDV 422
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855
W FG L EI G +P S+ ++ +R+ PE ++ L C + P+
Sbjct 423 WAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSD 482
Query 856 RPSFRTILRDLTRLQP 871
RPSF I + +
Sbjct 483 RPSFAEIHQAFETMFQ 498
Score = 295 bits (755), Expect = 5e-82, Method: Composition-based stats.
Identities = 94/310 (30%), Positives = 149/310 (48%), Gaps = 27/310 (9%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
P + T+ SP D + + LG G +G+V + + VA
Sbjct 214 HYPAPKRNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSL----TVA 269
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
VK LK D + +E +++ + H ++++ G C E ++ E++ G+L D
Sbjct 270 VKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLD 325
Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
YL R + LL A QI M YL +++IHRDLAARN L+ + LVK+ DFGL+
Sbjct 326 YLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLS 385
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + Y P+ W APE L KF SDVW+FGV L+E+ T+ S
Sbjct 386 RLMT--GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMS----- 438
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + ++ ELLE+ R+ RP+ CP +VY LM+ CW+ S RP+F +
Sbjct 439 ---------PYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
Query 1166 IPILKTVHEK 1175
+T+ ++
Sbjct 490 HQAFETMFQE 499
>sp|P06239|LCK_HUMAN Tyrosine-protein kinase Lck OS=Homo sapiens
OX=9606 GN=LCK PE=1 SV=6
Length=509
Score = 288 bits (737), Expect = 1e-84, Method: Composition-based stats.
Identities = 99/293 (34%), Positives = 149/293 (51%), Gaps = 29/293 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ LK + LG G FG+V + Y+ VAVK+LK G + E +
Sbjct 238 WEVPRETLKLVERLGAGQFGEVWMGYYNGH-----TKVAVKSLKQ--GSMSPDAFLAEAN 290
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQ 1006
+++ L H+ +++ ++ + ++ EY+ GSL D+L S + + +LL A Q
Sbjct 291 LMKQLQHQRLVRLYAVV---TQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQ 347
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I EGMA++ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+
Sbjct 348 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIK 405
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE + F SDVWSFG+ L E++TH I MT + +
Sbjct 406 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQ 451
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
LERG R+ RPD CP E+Y LM+ CW+ RPTF+ L +L+ +GQ
Sbjct 452 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATEGQ 504
Score = 287 bits (734), Expect = 2e-84, Method: Composition-based stats.
Identities = 86/404 (21%), Positives = 143/404 (35%), Gaps = 68/404 (17%)
Query 468 DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVR 527
G +LI S S L+V Q Q ++ + I D +FP +
Sbjct 148 HGSFLIRESESTAGSFSLSVRDFDQN----QGEVVKHYKIRNLDNGGFYISPRITFPGLH 203
Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587
EL + C L R C Q P+ V ++
Sbjct 204 ELVRHYTNA---SDGLCTRLSRPCQTQ---------------KPQKPWWE--DEWEVPRE 243
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ + LG G V+ G +V +K L
Sbjct 244 TLKLVERLGAGQFGEVWMG-------------------------YYNGHTKVAVKSLKQG 278
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HV 706
AF A+LM Q+ H L ++ V + ++TEY+E+G L +L+ G +
Sbjct 279 SMSP-DAFLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIKL 336
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ + +A Q+A ++++E +N +H ++ NIL++ + K++D G+
Sbjct 337 TINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS-------DTLSCKIADFGLARLI 389
Query 767 LSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
E I W APE + G + + D W FG L EI G P +
Sbjct 390 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP 447
Query 822 EKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
E +R +R+ P+ +L L C P RP+F +
Sbjct 448 EVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLR 491
>sp|Q5PXS1|LCK_AOTNA Tyrosine-protein kinase Lck OS=Aotus nancymaae
OX=37293 GN=LCK PE=2 SV=4
Length=509
Score = 288 bits (736), Expect = 1e-84, Method: Composition-based stats.
Identities = 103/293 (35%), Positives = 151/293 (52%), Gaps = 29/293 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ LK + LG G FG+V + Y ND T VAVK+LK G + E +
Sbjct 238 WEVPRETLKLVERLGAGQFGEVWMGYY---NDHT--KVAVKSLKQ--GSMSPDAFLAEAN 290
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQ 1006
+++ L H+ +++ ++ + ++ EY+ GSL D+L S + + +LL A Q
Sbjct 291 LMKQLQHQRLVRLYAVV---TQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQ 347
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I EGMA++ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+
Sbjct 348 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIK 405
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE + F SDVWSFG+ L E++TH I MT + +
Sbjct 406 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQ 451
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
LERG R+ RPD CP E+YHLM CW+ RPTF+ L +L+ +GQ
Sbjct 452 NLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLEDFFTATEGQ 504
Score = 286 bits (731), Expect = 6e-84, Method: Composition-based stats.
Identities = 86/404 (21%), Positives = 143/404 (35%), Gaps = 68/404 (17%)
Query 468 DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVR 527
G +LI S S L+V Q Q ++ + I D +FP +
Sbjct 148 HGSFLIRESESTAGSFSLSVRDFDQN----QGEVVKHYKIRNLDNGGFYISPRITFPGLH 203
Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587
EL + C L R C Q P+ V ++
Sbjct 204 ELVRHYTNA---SDGLCTRLSRPCQTQ---------------KPQKPWWE--DEWEVPRE 243
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ + LG G V+ G +V +K L
Sbjct 244 TLKLVERLGAGQFGEVWMG-------------------------YYNDHTKVAVKSLKQG 278
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HV 706
AF A+LM Q+ H L ++ V + ++TEY+E+G L +L+ G +
Sbjct 279 SMSP-DAFLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIKL 336
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ + +A Q+A ++++E +N +H ++ NIL++ + K++D G+
Sbjct 337 TINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS-------DTLSCKIADFGLARLI 389
Query 767 LSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
E I W APE + G + + D W FG L EI G P +
Sbjct 390 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP 447
Query 822 EKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
E +R +R+ P+ +L L C P RP+F +
Sbjct 448 EVIQNLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLR 491
>sp|P54756|EPHA5_HUMAN Ephrin type-A receptor 5 OS=Homo sapiens
OX=9606 GN=EPHA5 PE=1 SV=3
Length=1037
Score = 301 bits (770), Expect = 2e-84, Method: Composition-based stats.
Identities = 91/352 (26%), Positives = 157/352 (45%), Gaps = 24/352 (7%)
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR-----YL 897
+L +C + Q P + ++ + + + + + +
Sbjct 616 SLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCI 675
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
R +G G FG+V VA+K LK + R + E I+ H
Sbjct 676 TIERVIGAGEFGEVCSGRLKLPGKRE-LPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHP 734
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015
+II +G K + +V EY+ GSL +L ++ + QL+ + I GM YL
Sbjct 735 NIIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLS 792
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W APE +
Sbjct 793 DMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAF 852
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF ASDVWS+G+ ++E++++ + +MT + + +E G RLP
Sbjct 853 RKFTSASDVWSYGIVMWEVVSYGER--------------PYWEMTNQDVIKAVEEGYRLP 898
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC 1187
P CP +Y LM +CW+ E + RP F+ ++ +L + V + C
Sbjct 899 SPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASC 950
Score = 270 bits (691), Expect = 4e-74, Method: Composition-based stats.
Identities = 73/302 (24%), Positives = 123/302 (41%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
++ IT +G G V GRL++ G +EL V +
Sbjct 668 KEIEASCITIERVIGAGEFGEVCSGRLKLPGK---------------------RELPVAI 706
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +L+
Sbjct 707 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLK 766
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +++ + YL + VH ++ RNIL+ ++ K+SD
Sbjct 767 KNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 819
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E I W APE + ++A D W +G + E+ GE
Sbjct 820 GLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--FRKFTSASDVWSYGIVMWEVVSYGER 877
Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P + + + +RLP CP L L C E RP F I+ L +L
Sbjct 878 PYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIR 937
Query 872 HN 873
+
Sbjct 938 NP 939
>sp|P08631|HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo sapiens
OX=9606 GN=HCK PE=1 SV=5
Length=526
Score = 288 bits (736), Expect = 2e-84, Method: Composition-based stats.
Identities = 81/447 (18%), Positives = 151/447 (34%), Gaps = 71/447 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502
+ + + +L G ++I S + L+V Q +
Sbjct 140 ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDP----RQGDTV 195
Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562
+ + I D +F +++EL + C L C+
Sbjct 196 KHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGN---DGLCQKLSVPCM---------- 242
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
S + + + ++ + LG G V+
Sbjct 243 -------SSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMAT--------------- 280
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
+ +V +K + P + AF A++M + H L +H V +
Sbjct 281 ----------YNKHTKVAVKTMKPGSMSV-EAFLAEANVMKTLQHDKLVKLHAVVTK-EP 328
Query 683 NIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
++TE++ G L +L+ + G P+ + + Q+A ++++E +N +H ++ NIL
Sbjct 329 IYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANIL 388
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMD 796
++ S K++D G+ E I W APE + G S + D
Sbjct 389 VS-------ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFG--SFTIKSD 439
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854
W FG L+EI G P S E +R +R+ PE +L + +C P
Sbjct 440 VWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPE 499
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVN 881
+RP+F I L +
Sbjct 500 ERPTFEYIQSVLDDFYTATESQYQQQP 526
Score = 283 bits (725), Expect = 7e-83, Method: Composition-based stats.
Identities = 98/314 (31%), Positives = 154/314 (49%), Gaps = 29/314 (9%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
Q ++ + + D + LK + LG G FG+V + Y N T VA
Sbjct 234 CQKLSVPCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATY---NKHT--KVA 288
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
VK +K G + E ++++TL H+ ++K ++ + ++ E++ GSL D
Sbjct 289 VKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKLHAVV---TKEPIYIITEFMAKGSLLD 343
Query 989 YLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L L +L+ F+ QI EGMA++ ++YIHRDL A N+L+ + KI DFGLA
Sbjct 344 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLA 403
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + Y RE P+ W APE + F SDVWSFG+ L E++T+
Sbjct 404 RVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGR------ 455
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
I M+ + LERG R+PRP+ CP E+Y++M CW+ RPTFE +
Sbjct 456 --------IPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYI 507
Query 1166 IPILKTVHEKYQGQ 1179
+L + + Q
Sbjct 508 QSVLDDFYTATESQ 521
>sp|P54757|EPHA5_RAT Ephrin type-A receptor 5 OS=Rattus norvegicus
OX=10116 GN=Epha5 PE=1 SV=1
Length=1005
Score = 299 bits (765), Expect = 5e-84, Method: Composition-based stats.
Identities = 88/337 (26%), Positives = 153/337 (45%), Gaps = 24/337 (7%)
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFH-----KRYL 897
+L +C + Q P + ++ + + + + +
Sbjct 618 SLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPTQAVHEFGKEIEASCI 677
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
R +G G FG+V VA K LK + R + E I+ H
Sbjct 678 TIERVIGAGEFGEVCSGRLKLPGKRE-LPVATKTLKVGYTEKQRRDFLSEASIMGQFDHP 736
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015
+II +G K + +V EY+ GSL +L ++ + QL+ + I GM YL
Sbjct 737 NIIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLS 794
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W APE +
Sbjct 795 DMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAF 854
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
KF ASDVWS+G+ ++E++++ + +MT + + +E G RLP
Sbjct 855 RKFTSASDVWSYGIVMWEVVSYGER--------------PYWEMTNQDVIKAVEEGYRLP 900
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P CP +Y LM +CW+ + + RP F++++ +L +
Sbjct 901 SPMDCPAALYQLMLDCWQKDRNSRPKFDDIVNMLDKL 937
Score = 271 bits (693), Expect = 1e-74, Method: Composition-based stats.
Identities = 73/302 (24%), Positives = 122/302 (40%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
++ IT +G G V GRL++ G +EL V
Sbjct 670 KEIEASCITIERVIGAGEFGEVCSGRLKLPGK---------------------RELPVAT 708
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +L+
Sbjct 709 KTLKVGYTEKQRRDFLSEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLK 768
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL + VH ++ RNIL+ ++ K+SD
Sbjct 769 KNDGQFTVIQLVGMLRGIAAGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 821
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E I W APE + ++A D W +G + E+ GE
Sbjct 822 GLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--FRKFTSASDVWSYGIVMWEVVSYGER 879
Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P + + + +RLP CP L L C + RP F I+ L +L
Sbjct 880 PYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDDIVNMLDKLIR 939
Query 872 HN 873
+
Sbjct 940 NP 941
>sp|P29321|EPHA8_RAT Ephrin type-A receptor 8 (Fragment) OS=Rattus
norvegicus OX=10116 GN=Epha8 PE=2 SV=1
Length=372
Score = 281 bits (719), Expect = 6e-84, Method: Composition-based stats.
Identities = 91/293 (31%), Positives = 140/293 (48%), Gaps = 20/293 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+ +G G G+V VA+KALKA + R + +E I+ H
Sbjct 3 HIEKIIGSGESGEVCYGRLQVPGQRD-VPVAIKALKAGYTERQRQDFLREAAIMGQFDHP 61
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015
+II+ +G + +V EY+ GSL +L H + QL+ + + GM YL
Sbjct 62 NIIRLEGVVTRG--RLAMIVTEYMENGSLDAFLRTHDGQFTILQLVGMLKGVGAGMRYLS 119
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
YIHRDLAARN+L+D + K+ DFGL++A+ + E G P+ W APE +
Sbjct 120 DLGYIHRDLAARNILVDGRLVCKVSDFGLSRALEDDPEAAYTTAGGKIPIRWTAPEAIAF 179
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
F ASDVWSFGV ++E+L + + MT + +E G RLP
Sbjct 180 RTFSSASDVWSFGVVMWEVLAYGER--------------PYWNMTNQDVISSVEEGYRLP 225
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV-HEKYQGQAPSVFSVC 1187
P CP ++ LM +CW + + RP F +++ +L+ + H +A + S C
Sbjct 226 APMGCPRALHQLMLDCWHKDRAQRPRFSHVVSVLEALVHSPESLRATATVSRC 278
Score = 256 bits (654), Expect = 6e-75, Method: Composition-based stats.
Identities = 78/331 (24%), Positives = 128/331 (39%), Gaps = 46/331 (14%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
I +G G V GRL+V G +++ V +K L +
Sbjct 2 IHIEKIIGSGESGEVCYGRLQVPGQ---------------------RDVPVAIKALKAGY 40
Query 649 HDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
+ F A++M Q H ++ + GV RG ++VTEY+E+G LD +LR G
Sbjct 41 TERQRQDFLREAAIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDAFLRTHDGQFT 100
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
+ + + + + + + YL + +H ++ RNIL+ K+SD G+
Sbjct 101 ILQLVGMLKGVGAGMRYLSDLGYIHRDLAARNILVD-------GRLVCKVSDFGLSRALE 153
Query 768 SREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
E I W APE + + S+A D W FG + E+ GE P + +
Sbjct 154 DDPEAAYTTAGGKIPIRWTAPEAIA--FRTFSSASDVWSFGVVMWEVLAYGERPYWNMTN 211
Query 821 SEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + +RLP CP+ L L C + QRP F ++ L L +
Sbjct 212 QDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFSHVVSVLEALVHSPESLRA 271
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
T + + + DL G G
Sbjct 272 TATVSRCPAP------AFARSCFDLRAGGNG 296
>sp|P14238|FES_FELCA Tyrosine-protein kinase Fes/Fps OS=Felis
catus OX=9685 GN=FES PE=3 SV=2
Length=820
Score = 295 bits (754), Expect = 7e-84, Method: Composition-based stats.
Identities = 115/451 (25%), Positives = 177/451 (39%), Gaps = 85/451 (19%)
Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQ-AKLRPEDGLYLIHWSTSHPYRLILTVAQRSQ 492
L EV P + HG L P + A+L G +L+ S +L+V
Sbjct 445 LVPEVQKPL---HEQLWYHGAL--PRAEVAELLTHSGDFLVRESQGKQ-EYVLSV----- 493
Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552
DG R F IE D + LEG G F S+ L L LR+
Sbjct 494 LWDGQP----RHFIIESADNLYRLEGDG--FASIPLLVDHL----LRS------------ 531
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
QP + I++ A + ++ +++ +G+G V+ GRLR +
Sbjct 532 QQPLTKKSGIVLNRAVPKDK---------WVLNHEDLVLGEQIGRGNFGEVFSGRLRADN 582
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLA 671
V +K + DI F + A ++ Q SH ++
Sbjct 583 ------------------------TLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIV 618
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
+ GVC + +V E V+ G +LR E + M + + A+ + YLE+K +
Sbjct 619 RLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCI 678
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPECLP 785
H ++ RN L+ + +K+SD G+ A S R + W APE L
Sbjct 679 HRDLAARNCLVTEKNV-------LKISDFGMSREEADGIYAASGGLRQVPVKWTAPEALN 731
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LAT 843
G S+ D W FG L E G +P + S + F ++ RLP P CP +
Sbjct 732 YG--RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFR 789
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
L QC YEP QRPSF I ++L ++ +
Sbjct 790 LMEQCWAYEPGQRPSFSAIYQELQSIRKRHR 820
Score = 273 bits (698), Expect = 3e-76, Method: Composition-based stats.
Identities = 87/294 (30%), Positives = 139/294 (47%), Gaps = 23/294 (8%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
D V + L +G G+FG+V N +VAVK+ + P ++ +
Sbjct 548 PKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADN----TLVAVKSCRETLPPDIKAKFL 603
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLF 1003
QE IL+ H +I++ G C + + + +VME V G +L + + LL
Sbjct 604 QEAKILKQYSHPNIVRLIGVCTQK--QPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQM 661
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
GM YL ++ IHRDLAARN L+ ++KI DFG+++ +G Y
Sbjct 662 VGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGI-YAASGGLRQV 720
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
PV W APE L ++ SDVWSFG+ L+E + L ++ +
Sbjct 721 PVKWTAPEALNYGRYSSESDVWSFGILLWETFS--------------LGASPYPNLSNQQ 766
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
E +E+G RLP P+ CP V+ LM+ CW E RP+F + L+++ ++++
Sbjct 767 TREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQELQSIRKRHR 820
>sp|Q03145|EPHA2_MOUSE Ephrin type-A receptor 2 OS=Mus musculus
OX=10090 GN=Epha2 PE=1 SV=3
Length=977
Score = 297 bits (761), Expect = 1e-83, Method: Composition-based stats.
Identities = 86/307 (28%), Positives = 147/307 (48%), Gaps = 18/307 (6%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
L+ + + T H + + + +G G FG+V ++ V
Sbjct 585 PLKTYVDPHTYEDPNQAVLKFTTEIHPSCVARQKVIGAGEFGEVYKGTLKASSGKKEIPV 644
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LKA + R + E I+ H +II+ +G K + ++ EY+ G+L
Sbjct 645 AIKTLKAGYTEKQRVDFLSEASIMGQFSHHNIIRLEGVVSKY--KPMMIITEYMENGALD 702
Query 988 DYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL+
Sbjct 703 KFLREKDGEFSVLQLVGMLRGIASGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLS 762
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + E G P+ W APE + KF ASDVWS+G+ ++E++T+ +
Sbjct 763 RVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMTYGER----- 817
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+++ + + + G RLP P CP +Y LM CW+ E S RP F ++
Sbjct 818 ---------PYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADI 868
Query 1166 IPILKTV 1172
+ IL +
Sbjct 869 VSILDKL 875
Score = 270 bits (689), Expect = 5e-74, Method: Composition-based stats.
Identities = 76/299 (25%), Positives = 123/299 (41%), Gaps = 39/299 (13%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
+ + + +G G VY+G L+ +E+ V
Sbjct 606 TTEIHPSCVARQKVIGAGEFGEVYKGTLK--------------------ASSGKKEIPVA 645
Query 641 LKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+K L + + F AS+M Q SH ++ + GV + +++TEY+E+G LD +L
Sbjct 646 IKTLKAGYTEKQRVDFLSEASIMGQFSHHNIIRLEGVVSKYKPMMIITEYMENGALDKFL 705
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R + G + + + + +AS + YL N N VH ++ RNIL+ ++ K+SD
Sbjct 706 REKDGEFSVLQLVGMLRGIASGMKYLANMNYVHRDLAARNILVN-------SNLVCKVSD 758
Query 760 PGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
G+ E I W APE + ++A D W +G + E+ GE
Sbjct 759 FGLSRVLEDDPEATYTTSGGKIPIRWTAPEAIS--YRKFTSASDVWSYGIVMWEVMTYGE 816
Query 813 APLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
P S E RLP CP + L QC E ++RP F I+ L +L
Sbjct 817 RPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVSILDKL 875
>sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens
OX=9606 GN=ABL2 PE=1 SV=1
Length=1182
Score = 300 bits (769), Expect = 1e-83, Method: Composition-based stats.
Identities = 97/436 (22%), Positives = 158/436 (36%), Gaps = 70/436 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
HGP+ + L +G +L+ S S P +L +++ R+
Sbjct 169 EKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEG---------RVYH 219
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ I V F ++ EL A +L
Sbjct 220 YRINTTADGKVYVTAESRFSTLAELVHH---HSTVADGLVTTLHYPAPKC---------- 266
Query 565 RGARASPRTLNLSQL-SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
P +S + +++ +IT LG G VY G +
Sbjct 267 ----NKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYS----------- 311
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
L V +K L ++ F + A++M ++ H +L + GVC P
Sbjct 312 -------------LTVAVKTLKEDTMEV-EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPF 357
Query 684 IMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+VTEY+ +G L +LR R V + +A Q++SA+ YLE KN +H ++ RN L+
Sbjct 358 YIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV 417
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDK 797
G + +K++D G+ I W APE L N+ S D
Sbjct 418 -------GENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLA--YNTFSIKSDV 468
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855
W FG L EI G +P S+ ++ +R+ PE P++ L C + P
Sbjct 469 WAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPAD 528
Query 856 RPSFRTILRDLTRLQP 871
RPSF + +
Sbjct 529 RPSFAETHQAFETMFH 544
Score = 290 bits (742), Expect = 5e-80, Method: Composition-based stats.
Identities = 94/307 (31%), Positives = 148/307 (48%), Gaps = 27/307 (9%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
P + TV SP D + + LG G +G+V + + + VA
Sbjct 260 HYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSL----TVA 315
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
VK LK D + +E +++ + H ++++ G C E +V EY+P G+L D
Sbjct 316 VKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQLLGVCT--LEPPFYIVTEYMPYGNLLD 371
Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
YL R + LL A QI M YL +++IHRDLAARN L+ + +VK+ DFGL+
Sbjct 372 YLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLS 431
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + Y P+ W APE L F SDVW+FGV L+E+ T+ S
Sbjct 432 RLMT--GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMS----- 484
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + ++ +LLE+G R+ +P+ CP +VY LM+ CW+ + RP+F
Sbjct 485 ---------PYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAET 535
Query 1166 IPILKTV 1172
+T+
Sbjct 536 HQAFETM 542
>sp|O08680|EPHA3_RAT Ephrin type-A receptor 3 OS=Rattus norvegicus
OX=10116 GN=Epha3 PE=2 SV=1
Length=984
Score = 297 bits (761), Expect = 1e-83, Method: Composition-based stats.
Identities = 86/306 (28%), Positives = 144/306 (47%), Gaps = 19/306 (6%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
L+ + + + + +G G FG+V + VA
Sbjct 594 LRTYVDPHTYEDPTQAVHEFAKELDATNIAIDKVVGAGEFGEVCSGRLKLPSKKE-ISVA 652
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK + R + E I+ H +II+ +G K + +V EY+ GSL
Sbjct 653 IKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKS--KPVMIVTEYMENGSLDS 710
Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
+L +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL++
Sbjct 711 FLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSR 770
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
+ + E G PV W +PE KF ASDVWS+G+ L+E++++ +
Sbjct 771 VLEDDPEAAYTTRGGKIPVRWTSPEATAYRKFTSASDVWSYGIVLWEVMSYGER------ 824
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+M+ + + ++ G RLP P CP +Y LM +CW+ + + RP FE ++
Sbjct 825 --------PYWEMSNQDVIKAVDEGYRLPLPMDCPAALYQLMLDCWQKDRNNRPKFEQIV 876
Query 1167 PILKTV 1172
IL +
Sbjct 877 SILDKL 882
Score = 271 bits (692), Expect = 2e-74, Method: Composition-based stats.
Identities = 74/302 (25%), Positives = 120/302 (40%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D I +G G V GRL++ +E+ V +
Sbjct 615 KELDATNIAIDKVVGAGEFGEVCSGRLKLPSK---------------------KEISVAI 653
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +LR
Sbjct 654 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLR 713
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ + + + + +AS + YL + VH ++ RNIL+ ++ K+SD
Sbjct 714 KHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 766
Query 761 GVGLGALSR-----EERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ R +IP W +PE ++A D W +G L E+ GE
Sbjct 767 GLSRVLEDDPEAAYTTRGGKIPVRWTSPEA--TAYRKFTSASDVWSYGIVLWEVMSYGER 824
Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + +RLP CP L L C + RP F I+ L +L
Sbjct 825 PYWEMSNQDVIKAVDEGYRLPLPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIR 884
Query 872 HN 873
+
Sbjct 885 NP 886
>sp|P00522|ABL_DROME Tyrosine-protein kinase Abl OS=Drosophila
melanogaster OX=7227 GN=Abl PE=1 SV=3
Length=1620
Score = 303 bits (776), Expect = 2e-83, Method: Composition-based stats.
Identities = 100/444 (23%), Positives = 164/444 (37%), Gaps = 69/444 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDG 496
V P + HGP+ + L +G +L+ S S P + +++
Sbjct 243 VTPLNSLEK-HSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG----- 296
Query 497 MQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPG 556
R+ + I + V F ++ EL L Q
Sbjct 297 ----RVYHYRISEDPDGKVFVTQEAKFNTLAELVHHHSVPH-EGHGLITPLLYPAPKQ-- 349
Query 557 ETSNLIIMRGARASPRTLNLS-QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615
P LS + + + +I LG G VYE + G+
Sbjct 350 ------------NKPTVFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGN-- 395
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675
V +K L F E A++M ++ H +L + G
Sbjct 396 ----------------------TVAVKTLKEDTM-ALKDFLEEAAIMKEMKHPNLVQLIG 432
Query 676 VCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGN 734
VC R P ++TE++ HG L +LR R + + +A Q+AS +SYLE++N +H +
Sbjct 433 VCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRD 492
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGAN 789
+ RN L+ G + +K++D G+ I W APE L N
Sbjct 493 LAARNCLV-------GDNKLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLA--YN 543
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847
ST D W FG L EI G +P + ++ H + +R+ P P++ L Q
Sbjct 544 KFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQ 603
Query 848 CLTYEPTQRPSFRTILRDLTRLQP 871
C ++ T RP+F++I L +
Sbjct 604 CWQWDATDRPTFKSIHHALEHMFQ 627
Score = 301 bits (771), Expect = 7e-83, Method: Composition-based stats.
Identities = 102/310 (33%), Positives = 160/310 (52%), Gaps = 27/310 (9%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
L P + TV P SP D + + LG G +G+V Y+ G VA
Sbjct 343 LYPAPKQNKPTVFPLSPEPDEWEICRTDIMMKHKLGGGQYGEV----YEAVWKRYGNTVA 398
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
VK LK D + +E I++ + H ++++ G C E ++ E++ G+L D
Sbjct 399 VKTLKEDT--MALKDFLEEAAIMKEMKHPNLVQLIGVCTR--EPPFYIITEFMSHGNLLD 454
Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L R ++ LL A QI GM+YL +++YIHRDLAARN L+ +++LVK+ DFGLA
Sbjct 455 FLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLA 514
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + + Y P+ W APE L KF SDVW+FGV L+E+ T+ S
Sbjct 515 RLMRD--DTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMS----- 567
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + + L++G R+ RP CP EVY LM+ CW+ +A+ RPTF+++
Sbjct 568 ---------PYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSI 618
Query 1166 IPILKTVHEK 1175
L+ + ++
Sbjct 619 HHALEHMFQE 628
>sp|P29318|EPHA3_CHICK Ephrin type-A receptor 3 OS=Gallus gallus
OX=9031 GN=EPHA3 PE=1 SV=1
Length=983
Score = 296 bits (758), Expect = 3e-83, Method: Composition-based stats.
Identities = 85/306 (28%), Positives = 145/306 (47%), Gaps = 19/306 (6%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
L+ + + + + +G G FG+V + VA
Sbjct 593 LRTYVDPHTYEDPNQAVHEFAKELDASNISIDKVVGAGEFGEVCSGRLKLPSKKE-ISVA 651
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LKA + R + E I+ H +II+ +G K + +V EY+ GSL
Sbjct 652 IKTLKAGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKS--KPVMIVTEYMENGSLDS 709
Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
+L +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL++
Sbjct 710 FLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSR 769
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
+ + E G P+ W +PE + KF ASD WS+G+ L+E++++ +
Sbjct 770 VLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDAWSYGIVLWEVMSYGER------ 823
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+M+ + + ++ G RLP P CP +Y LM +CW+ + + RP FE ++
Sbjct 824 --------PYWEMSFQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIV 875
Query 1167 PILKTV 1172
IL +
Sbjct 876 SILDKL 881
Score = 269 bits (688), Expect = 6e-74, Method: Composition-based stats.
Identities = 74/302 (25%), Positives = 121/302 (40%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D I+ +G G V GRL++ +E+ V +
Sbjct 614 KELDASNISIDKVVGAGEFGEVCSGRLKLPSK---------------------KEISVAI 652
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +LR
Sbjct 653 KTLKAGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLR 712
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ + + + + +AS + YL + VH ++ RNIL+ ++ K+SD
Sbjct 713 KHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 765
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E I W +PE + ++A D W +G L E+ GE
Sbjct 766 GLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIA--YRKFTSASDAWSYGIVLWEVMSYGER 823
Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + +RLP P CP L L C + RP F I+ L +L
Sbjct 824 PYWEMSFQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIR 883
Query 872 HN 873
+
Sbjct 884 NP 885
>sp|P16879|FES_MOUSE Tyrosine-protein kinase Fes/Fps OS=Mus musculus
OX=10090 GN=Fes PE=1 SV=2
Length=822
Score = 293 bits (749), Expect = 4e-83, Method: Composition-based stats.
Identities = 107/451 (24%), Positives = 177/451 (39%), Gaps = 85/451 (19%)
Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQ-AKLRPEDGLYLIHWSTSHPYRLILTVAQRSQ 492
L EV P + HG + P + A+L G +L+ S +L+V
Sbjct 447 LVPEVQKPLY---EQLWYHGAI--PRAEVAELLTHSGDFLVRESQGKQ-EYVLSV----- 495
Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552
DG R F I+ D + LEG G FPS+ L L
Sbjct 496 MWDGQP----RHFIIQSSDNLYRLEGDG--FPSIPLLITHLLSS---------------- 533
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
QP + +++ A + + +++ +G+G V+ GRLR +
Sbjct 534 QQPLTKKSGVVLFRAVPKDK---------WVLKHEDLVLGEQIGRGNFGEVFSGRLRADN 584
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLA 671
V +K + D+ F + A ++ Q +H ++
Sbjct 585 ------------------------TPVAVKSCRETLPPDLKAKFLQEARILKQYNHPNIV 620
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
+ GVC + +V E V+ G +LR E + + + + A+ + YLE+K +
Sbjct 621 RLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCI 680
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIP--WLAPECLP 785
H ++ RN L+ + +K+SD G+ G + + ++P W APE L
Sbjct 681 HRDLAARNCLVTEKNV-------LKISDFGMSREEADGIYAASAGLRQVPVKWTAPEALN 733
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LAT 843
G S+ D W FG L E G +P + + + F ++ HRLP P CP +
Sbjct 734 YG--RYSSESDVWSFGILLWETFSLGASPYPNLTNQQTREFVEKGHRLPCPELCPDAVFR 791
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
L QC YEP QRPSF I ++L ++ +
Sbjct 792 LMEQCWAYEPGQRPSFSIICQELHSIRKRHR 822
Score = 270 bits (691), Expect = 2e-75, Method: Composition-based stats.
Identities = 94/331 (28%), Positives = 145/331 (44%), Gaps = 23/331 (7%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
E PS ++ L Q V + D V L +G G+F
Sbjct 513 YRLEGDGFPSIPLLITHLLSSQQPLTKKSGVVLFRAVPKDKWVLKHEDLVLGEQIGRGNF 572
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968
G+V N VAVK+ + P ++ + QE IL+ H +I++ G C
Sbjct 573 GEVFSGRLRADN----TPVAVKSCRETLPPDLKAKFLQEARILKQYNHPNIVRLIGVCTQ 628
Query 969 QGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
+ + + +VME V G +L + + LL GM YL ++ IHRDLAA
Sbjct 629 K--QPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAA 686
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RN L+ ++KI DFG+++ +G Y PV W APE L ++ SDVWS
Sbjct 687 RNCLVTEKNVLKISDFGMSREEADGI-YAASAGLRQVPVKWTAPEALNYGRYSSESDVWS 745
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
FG+ L+E + L +T + E +E+G RLP P+ CP V+
Sbjct 746 FGILLWETFS--------------LGASPYPNLTNQQTREFVEKGHRLPCPELCPDAVFR 791
Query 1147 LMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
LM+ CW E RP+F + L ++ ++++
Sbjct 792 LMEQCWAYEPGQRPSFSIICQELHSIRKRHR 822
>sp|P00541|FPS_AVISP Tyrosine-protein kinase transforming protein
Fps OS=Avian sarcoma virus (strain PRCII) OX=11880 GN=V-FPS
PE=3 SV=1
Length=533
Score = 285 bits (728), Expect = 4e-83, Method: Composition-based stats.
Identities = 98/436 (22%), Positives = 171/436 (39%), Gaps = 80/436 (18%)
Query 448 RDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPI 507
+ HG + VQ +L G +L+ S +L+V DG R F I
Sbjct 169 QAWYHGAIPRSEVQ-ELLKCSGDFLVRESQGKQ-EYVLSV-----LWDGQP----RHFII 217
Query 508 EQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGA 567
+ D + LEG G FP++ L L QP + I++ A
Sbjct 218 QAADNLYRLEGDG--FPTIPLLIDHLLQS----------------QQPITRKSGIVLTRA 259
Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
+ ++ +++ +G+G V+ GRLR +
Sbjct 260 VLKDK---------WVLNHEDVLLGERIGRGNFGEVFSGRLRADN--------------- 295
Query 628 VPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
V +K + ++ F + A ++ Q +H ++ + GVC + +V
Sbjct 296 ---------TPVAVKSCRETLPPELKAKFLQEARILKQYNHPNIVRLIGVCTQKQPIYIV 346
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
E V+ G +LR + H+ M + + + A+ + YLE+K+ +H ++ RN L+
Sbjct 347 MELVQGGDFLSFLRSKGPHLKMKELIKMMENAAAGMEYLESKHCIHRDLAARNCLVTEKN 406
Query 747 LAEGTSPFIKLSDPGVGL----GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGF 800
+K+SD G+ G + +++IP W APE L G S+ D W F
Sbjct 407 -------TLKISDFGMSRQEEDGVYASTGGMKQIPVKWTAPEALNYG--RYSSESDVWSF 457
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPS 858
G L E G P + S + ++ RL PE + L +C Y+P +RPS
Sbjct 458 GILLWEAFSLGAVPYANLSNQQTREAIEQGVRLEPPEQCPEDVYRLMQRCWEYDPRRRPS 517
Query 859 FRTILRDLTRLQPHNL 874
F + +DL ++ +
Sbjct 518 FGAVHQDLIAIRKRHR 533
Score = 273 bits (697), Expect = 7e-79, Method: Composition-based stats.
Identities = 91/331 (27%), Positives = 152/331 (46%), Gaps = 23/331 (7%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
E P+ ++ L + Q V + D V + + +G G+F
Sbjct 224 YRLEGDGFPTIPLLIDHLLQSQQPITRKSGIVLTRAVLKDKWVLNHEDVLLGERIGRGNF 283
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968
G+V N VAVK+ + P+ ++ + QE IL+ H +I++ G C
Sbjct 284 GEVFSGRLRADN----TPVAVKSCRETLPPELKAKFLQEARILKQYNHPNIVRLIGVCTQ 339
Query 969 QGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
+ + + +VME V G +L + + +L+ + GM YL ++H IHRDLAA
Sbjct 340 K--QPIYIVMELVQGGDFLSFLRSKGPHLKMKELIKMMENAAAGMEYLESKHCIHRDLAA 397
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RN L+ +KI DFG+++ +G Y PV W APE L ++ SDVWS
Sbjct 398 RNCLVTEKNTLKISDFGMSRQEEDGV-YASTGGMKQIPVKWTAPEALNYGRYSSESDVWS 456
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
FG+ L+E + L + ++ + E +E+G RL P++CP +VY
Sbjct 457 FGILLWEAFS--------------LGAVPYANLSNQQTREAIEQGVRLEPPEQCPEDVYR 502
Query 1147 LMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
LM+ CWE + RP+F + L + ++++
Sbjct 503 LMQRCWEYDPRRRPSFGAVHQDLIAIRKRHR 533
>sp|O13146|EPHA3_DANRE Ephrin type-A receptor 3 OS=Danio rerio
OX=7955 GN=epha3 PE=1 SV=1
Length=981
Score = 295 bits (754), Expect = 1e-82, Method: Composition-based stats.
Identities = 90/334 (27%), Positives = 154/334 (46%), Gaps = 24/334 (7%)
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR-----YLKKI 900
+C + Q P + R++ + + + + ++
Sbjct 570 RRCGYIKAKQDPEEEKMQFQHGRVKLPETRTYIHPHTYEDPNQAVRDFAKEIEVSNIRIE 629
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
R +G G FG+V + + VA+K+LKA R + E I+ H +II
Sbjct 630 RVIGAGEFGEVCSGRLRLPSKREIQ-VAIKSLKAGYSEHQRRDFLSEASIMGQFDHPNII 688
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018
+ +G K + +V EY+ GSL +L +H + QLL + I GM YL +
Sbjct 689 RLEGVVTRC--KPVMIVTEYMENGSLDTFLKKHDGQFTVIQLLGMLRGIAAGMQYLSEMN 746
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
Y+HRDLAARN+L++ + + K+ DFGL++ + + E G P+ W APE + KF
Sbjct 747 YVHRDLAARNILVNRNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAITYRKF 806
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
ASDVWS+G+ ++E++++ + +M+ + + ++ G RLP P
Sbjct 807 TSASDVWSYGIVMWEVISYGER--------------PYWEMSNQDVIKAVDEGYRLPAPM 852
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
CP ++ LM +CWE S RP F ++ L +
Sbjct 853 DCPVVLHQLMLDCWEKNRSDRPKFGQIVNTLDRL 886
Score = 275 bits (704), Expect = 5e-76, Method: Composition-based stats.
Identities = 79/341 (23%), Positives = 129/341 (38%), Gaps = 42/341 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
++ I +G G V GRLR+ +E++V +
Sbjct 619 KEIEVSNIRIERVIGAGEFGEVCSGRLRLPSK---------------------REIQVAI 657
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV R ++VTEY+E+G LD +L+
Sbjct 658 KSLKAGYSEHQRRDFLSEASIMGQFDHPNIIRLEGVVTRCKPVMIVTEYMENGSLDTFLK 717
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL N VH ++ RNIL+ R + K+SD
Sbjct 718 KHDGQFTVIQLLGMLRGIAAGMQYLSEMNYVHRDLAARNILVNR-------NLVCKVSDF 770
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E I W APE + ++A D W +G + E+ GE
Sbjct 771 GLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIT--YRKFTSASDVWSYGIVMWEVISYGER 828
Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + +RLP CP L L C + RP F I+ L RL
Sbjct 829 PYWEMSNQDVIKAVDEGYRLPAPMDCPVVLHQLMLDCWEKNRSDRPKFGQIVNTLDRLIR 888
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIR--DLGEGHFGK 910
+ + N T + + G + +
Sbjct 889 NPSSLKQLANSAVWEDPVTPEAAVNTVEDWLDLIKMGQYKE 929
>sp|P29319|EPHA3_MOUSE Ephrin type-A receptor 3 OS=Mus musculus
OX=10090 GN=Epha3 PE=1 SV=1
Length=983
Score = 295 bits (754), Expect = 1e-82, Method: Composition-based stats.
Identities = 84/306 (27%), Positives = 143/306 (47%), Gaps = 19/306 (6%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
L+ + + + + +G G FG+V + VA
Sbjct 593 LRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKE-ISVA 651
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK + R + E I+ H +II+ +G + +V EY+ GSL
Sbjct 652 IKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPE--MIVTEYMENGSLDS 709
Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
+L +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL++
Sbjct 710 FLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSR 769
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
+ + E G P+ W +PE + KF ASDVWS+G+ L+E++++ +
Sbjct 770 VLEDDPEAAYTTRGGKIPIRWTSPEAMSYRKFTSASDVWSYGIVLWEVMSYGER------ 823
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
QM+ + + ++ RLP P CP +Y LM +CW+ + + RP FE ++
Sbjct 824 --------PYSQMSNQDVIKAVDERYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIV 875
Query 1167 PILKTV 1172
IL +
Sbjct 876 SILDKL 881
Score = 269 bits (687), Expect = 7e-74, Method: Composition-based stats.
Identities = 74/302 (25%), Positives = 122/302 (40%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D I+ +G G V GRL++ +E+ V +
Sbjct 614 KELDATNISIDKVVGAGEFGEVCSGRLKLPSK---------------------KEISVAI 652
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +LR
Sbjct 653 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPEMIVTEYMENGSLDSFLR 712
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ + + + + +AS + YL + VH ++ RNIL+ ++ K+SD
Sbjct 713 KHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 765
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E I W +PE + ++A D W +G L E+ GE
Sbjct 766 GLSRVLEDDPEAAYTTRGGKIPIRWTSPEAMS--YRKFTSASDVWSYGIVLWEVMSYGER 823
Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + ++RLP P CP L L C + RP F I+ L +L
Sbjct 824 PYSQMSNQDVIKAVDERYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIR 883
Query 872 HN 873
+
Sbjct 884 NP 885
>sp|Q4JIM5|ABL2_MOUSE Tyrosine-protein kinase ABL2 OS=Mus musculus
OX=10090 GN=Abl2 PE=1 SV=1
Length=1182
Score = 297 bits (760), Expect = 2e-82, Method: Composition-based stats.
Identities = 96/436 (22%), Positives = 158/436 (36%), Gaps = 70/436 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
HGP+ + L +G +L+ S S P +L +++ R+
Sbjct 169 EKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEG---------RVYH 219
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ I + V F ++ EL A +L
Sbjct 220 YRINTTTDSKVYVTAESRFSTLAELVHH---HSTVADGLVTTLHYPAPKC---------- 266
Query 565 RGARASPRTLNLSQL-SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
P +S + +++ +IT LG G VY G +
Sbjct 267 ----NKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYS----------- 311
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
L V +K ++ F + A++M ++ H +L + GVC P
Sbjct 312 -------------LTVAVKTFKEDTMEV-EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPF 357
Query 684 IMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+VTEY+ +G L +LR R V + +A Q++SA+ YLE KN +H ++ RN L+
Sbjct 358 YIVTEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV 417
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDK 797
G + +K++D G+ I W APE L N+ S D
Sbjct 418 -------GENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLA--YNTFSIKSDV 468
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855
W FG L EI G +P S+ ++ +R+ PE P++ L C + P
Sbjct 469 WAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPAD 528
Query 856 RPSFRTILRDLTRLQP 871
RPSF + +
Sbjct 529 RPSFAETHQAFETMFH 544
Score = 289 bits (739), Expect = 1e-79, Method: Composition-based stats.
Identities = 93/307 (30%), Positives = 147/307 (48%), Gaps = 27/307 (9%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
P + TV SP D + + LG G +G+V + + + VA
Sbjct 260 HYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSL----TVA 315
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
VK K D + +E +++ + H ++++ G C E +V EY+P G+L D
Sbjct 316 VKTFKEDT--MEVEEFLKEAAVMKEIKHPNLVQLLGVCT--LEPPFYIVTEYMPYGNLLD 371
Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
YL R + LL A QI M YL +++IHRDLAARN L+ + +VK+ DFGL+
Sbjct 372 YLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLS 431
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + Y P+ W APE L F SDVW+FGV L+E+ T+ S
Sbjct 432 RLMT--GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMS----- 484
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + ++ +LLE+G R+ +P+ CP +VY LM+ CW+ + RP+F
Sbjct 485 ---------PYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAET 535
Query 1166 IPILKTV 1172
+T+
Sbjct 536 HQAFETM 542
>sp|P08103|HCK_MOUSE Tyrosine-protein kinase HCK OS=Mus musculus
OX=10090 GN=Hck PE=1 SV=4
Length=524
Score = 282 bits (722), Expect = 2e-82, Method: Composition-based stats.
Identities = 82/447 (18%), Positives = 149/447 (33%), Gaps = 71/447 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502
+ + + L G ++I S + L+V +
Sbjct 138 ETEEWFFKGISRKDAERHLLAPGNMLGSFMIRDSETTKGSYSLSVRDFDP----QHGDTV 193
Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562
+ + I D +F S++EL + C L C+
Sbjct 194 KHYKIRTLDSGGFYISPRSTFSSLQELVLHYKKGK---DGLCQKLSVPCV---------- 240
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
SP+ + + ++ + LG G V+
Sbjct 241 -------SPKPQKPWEKDAWEIPRESLQMEKKLGAGQFGEVWMAT--------------- 278
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
+ +V +K + P + AF A+LM + H L +H V +
Sbjct 279 ----------YNKHTKVAVKTMKPGSMSV-EAFLAEANLMKSLQHDKLVKLHAVVSQ-EP 326
Query 683 NIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
+VTE++ G L +L+ E G P+ + + Q++ ++++E +N +H ++ NIL
Sbjct 327 IFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQISEGMAFIEQRNYIHRDLRAANIL 386
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMD 796
++ S K++D G+ E I W APE + G S + D
Sbjct 387 VS-------ASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFG--SFTIKSD 437
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854
W FG L+EI G P S E + +R+ P+ +L + +C P
Sbjct 438 VWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNCPEELYNIMIRCWKNRPE 497
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVN 881
+RP+F I L +
Sbjct 498 ERPTFEYIQSVLDDFYTATESQYQQQP 524
Score = 280 bits (717), Expect = 1e-81, Method: Composition-based stats.
Identities = 95/293 (32%), Positives = 147/293 (50%), Gaps = 29/293 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ L+ + LG G FG+V + Y N T VAVK +K G + E +
Sbjct 253 WEIPRESLQMEKKLGAGQFGEVWMATY---NKHT--KVAVKTMKP--GSMSVEAFLAEAN 305
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQ 1006
++++L H+ ++K ++ + +V E++ GSL D+L L +L+ F+ Q
Sbjct 306 LMKSLQHDKLVKLHAVV---SQEPIFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQ 362
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I EGMA++ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+
Sbjct 363 ISEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNE--YTAREGAKFPIK 420
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE + F SDVWSFG+ L E++T+ I M+ +
Sbjct 421 WTAPEAINFGSFTIKSDVWSFGILLMEIVTYGR--------------IPYPGMSNPEVIR 466
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
LE G R+PRPD CP E+Y++M CW+ RPTFE + +L + + Q
Sbjct 467 ALEHGYRMPRPDNCPEELYNIMIRCWKNRPEERPTFEYIQSVLDDFYTATESQ 519
>sp|P16277|BLK_MOUSE Tyrosine-protein kinase Blk OS=Mus musculus
OX=10090 GN=Blk PE=1 SV=4
Length=499
Score = 281 bits (719), Expect = 2e-82, Method: Composition-based stats.
Identities = 85/437 (19%), Positives = 159/437 (36%), Gaps = 73/437 (17%)
Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
VAP + + + + +L + G +LI S S+ L+V +
Sbjct 107 VAPVETLE-VEKWFFRTISRKDAERQLLAPMNKAGSFLIRESESNKGAFSLSVKDITTQG 165
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
+ ++ ++R D +FP+++ L C L C+
Sbjct 166 EVVKHYKIR-----SLDNGGYYISPRITFPTLQALVQHYSKKG---DGLCQKLTLPCV-- 215
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+ NL + ++ + + LG G V+ G +
Sbjct 216 ---------------NLAPKNLWAQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNN--- 257
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
++V +K L AF A++M + H L ++
Sbjct 258 ----------------------MKVAIKTLKEGTMSP-EAFLGEANVMKTLQHERLVRLY 294
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHG 733
V R +VTEY+ G L +L+ + G + + + ++ Q+A ++Y+E N +H
Sbjct 295 AVVTR-EPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMAYIERMNSIHR 353
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGAN 789
++ NIL++ + K++D G+ ++E I W APE + G
Sbjct 354 DLRAANILVSE-------TLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGV- 405
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLA-TLTS 846
+ D W FG L+EI G P S E + +R+P P P+L + +
Sbjct 406 -FTIKADVWSFGVLLMEIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPELYNDIIT 464
Query 847 QCLTYEPTQRPSFRTIL 863
+C P +RP+F +
Sbjct 465 ECWRGRPEERPTFEFLQ 481
Score = 273 bits (699), Expect = 1e-79, Method: Composition-based stats.
Identities = 92/297 (31%), Positives = 141/297 (47%), Gaps = 31/297 (10%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
D ++ LK +R LG G FG+V + Y VA+K LK G +
Sbjct 225 QDEWEIPRQSLKLVRKLGSGQFGEVWMGYYK-----NNMKVAIKTLKE--GTMSPEAFLG 277
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLF 1003
E ++++TL HE +++ + + +V EY+ G L D+L + L +L+
Sbjct 278 EANVMKTLQHERLVRLYAVV---TREPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDM 334
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+ Q+ EGMAY+ + IHRDL A N+L+ KI DFGLA+ + Y +E
Sbjct 335 SAQVAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARII---DSEYTAQEGAKF 391
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
P+ W APE + F +DVWSFGV L E++T+ + M+
Sbjct 392 PIKWTAPEAIHFGVFTIKADVWSFGVLLMEIVTYGR--------------VPYPGMSNPE 437
Query 1124 LTELLERGERLPRPDKCPCEVY-HLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+ LE G R+P P+ CP E+Y ++ CW RPTFE L +L+ + +GQ
Sbjct 438 VIRSLEHGYRMPCPETCPPELYNDIITECWRGRPEERPTFEFLQSVLEDFYTATEGQ 494
>sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens
OX=9606 GN=EPHA2 PE=1 SV=2
Length=976
Score = 293 bits (751), Expect = 3e-82, Method: Composition-based stats.
Identities = 86/307 (28%), Positives = 147/307 (48%), Gaps = 18/307 (6%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
L+ + + T H + + + +G G FG+V ++ V
Sbjct 584 PLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPV 643
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LKA + R + E I+ H +II+ +G K + ++ EY+ G+L
Sbjct 644 AIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKY--KPMMIITEYMENGALD 701
Query 988 DYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL+
Sbjct 702 KFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLS 761
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + E G P+ W APE + KF ASDVWSFG+ ++E++T+ +
Sbjct 762 RVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGER----- 816
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+++ + + + G RLP P CP +Y LM CW+ E + RP F ++
Sbjct 817 ---------PYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADI 867
Query 1166 IPILKTV 1172
+ IL +
Sbjct 868 VSILDKL 874
Score = 268 bits (685), Expect = 1e-73, Method: Composition-based stats.
Identities = 76/299 (25%), Positives = 122/299 (41%), Gaps = 39/299 (13%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
+ +T+ +G G VY+G L+ +E+ V
Sbjct 605 TTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSG--------------------KKEVPVA 644
Query 641 LKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+K L + + F A +M Q SH ++ + GV + +++TEY+E+G LD +L
Sbjct 645 IKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFL 704
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R + G + + + + +A+ + YL N N VH ++ RNIL+ ++ K+SD
Sbjct 705 REKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVN-------SNLVCKVSD 757
Query 760 PGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
G+ E I W APE + ++A D W FG + E+ GE
Sbjct 758 FGLSRVLEDDPEATYTTSGGKIPIRWTAPEAIS--YRKFTSASDVWSFGIVMWEVMTYGE 815
Query 813 APLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
P S E RLP CP + L QC E +RP F I+ L +L
Sbjct 816 RPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKL 874
>sp|P42681|TXK_HUMAN Tyrosine-protein kinase TXK OS=Homo sapiens
OX=9606 GN=TXK PE=1 SV=3
Length=527
Score = 282 bits (721), Expect = 3e-82, Method: Composition-based stats.
Identities = 87/426 (20%), Positives = 159/426 (37%), Gaps = 64/426 (15%)
Query 446 SIRDGIHGPLLEPFVQAKLRPE--DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLR 503
I + H + + LR E +G +++ S H ++V ++ ++
Sbjct 146 EIYEWYHRNITRNQAEHLLRQESKEGAFIVRDS-RHLGSYTISVFMGARRSTEAA---IK 201
Query 504 KFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLII 563
+ I++ D +F S+ EL Q A LR +
Sbjct 202 HYQIKKNDSGQWYVAERHAFQSIPELIWYHQHN---AAGLMTRLRYP------------V 246
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
P T S +D E+ + +G G V+ G R
Sbjct 247 GLMGSCLPATAGFSY-EKWEIDPSELAFIKEIGSGQFGVVHLGEWR-------------- 291
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
++V +K ++ F E A +M ++SH+ L ++GVC++
Sbjct 292 -----------SHIQVAIKAINEGSMS-EEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPL 339
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+VTE++E+G L +LR +G + + V Q + + YLE +H ++ RN L++
Sbjct 340 YIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVS 399
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKW 798
++ +K+SD G+ L E I W PE N S+ D W
Sbjct 400 -------STCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFL--FNKYSSKSDVW 450
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
FG + E+ +G+ P +++S + RL P + + + C +P R
Sbjct 451 SFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGR 510
Query 857 PSFRTI 862
P+F +
Sbjct 511 PTFAEL 516
Score = 256 bits (655), Expect = 3e-73, Method: Composition-based stats.
Identities = 89/302 (29%), Positives = 134/302 (44%), Gaps = 27/302 (9%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+ + L I+++G G FG V L + + VA+KA+
Sbjct 249 MGSCLPATAGFSYEKWEIDPSELAFIKEIGSGQFGVVHLGEWR-----SHIQVAIKAINE 303
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994
G + +E ++ L H +++ G C + K L +V E++ G L +YL +
Sbjct 304 --GSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQR--KPLYIVTEFMENGCLLNYLRENK 359
Query 995 IGL--AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
L LL Q ICEGM YL YIHRDLAARN L+ + +VKI DFG+ + V +
Sbjct 360 GKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDE 419
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
Y P+ W PE K+ SDVWSFGV ++E+ T
Sbjct 420 --YVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGK------------- 464
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ + L++ E + G RL RP P +Y +M +CW + RPTF L+ + +
Sbjct 465 -MPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEI 523
Query 1173 HE 1174
E
Sbjct 524 AE 525
>sp|P07332|FES_HUMAN Tyrosine-protein kinase Fes/Fps OS=Homo sapiens
OX=9606 GN=FES PE=1 SV=3
Length=822
Score = 290 bits (741), Expect = 4e-82, Method: Composition-based stats.
Identities = 107/451 (24%), Positives = 174/451 (39%), Gaps = 85/451 (19%)
Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQ-AKLRPEDGLYLIHWSTSHPYRLILTVAQRSQ 492
L EV P + HG + P + A+L G +L+ S +L+V
Sbjct 447 LIPEVQKPL---HEQLWYHGAI--PRAEVAELLVHSGDFLVRESQGKQ-EYVLSV----- 495
Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552
DG+ R F I+ D + LEG G FPS+ L L
Sbjct 496 LWDGLP----RHFIIQSLDNLYRLEGEG--FPSIPLLIDHLLS----------------T 533
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
QP + +++ A + ++ +++ +G+G V+ GRLR +
Sbjct 534 QQPLTKKSGVVLHRAVPKDK---------WVLNHEDLVLGEQIGRGNFGEVFSGRLRADN 584
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLA 671
V +K + D+ F + A ++ Q SH ++
Sbjct 585 ------------------------TLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIV 620
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
+ GVC + +V E V+ G +LR E + + + + A+ + YLE+K +
Sbjct 621 RLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCI 680
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLP 785
H ++ RN L+ + +K+SD G+ + W APE L
Sbjct 681 HRDLAARNCLVTEKNV-------LKISDFGMSREEADGVYAASGGLRQVPVKWTAPEALN 733
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LAT 843
G S+ D W FG L E G +P + S + F ++ RLP P CP +
Sbjct 734 YG--RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFR 791
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
L QC YEP QRPSF TI ++L ++ +
Sbjct 792 LMEQCWAYEPGQRPSFSTIYQELQSIRKRHR 822
Score = 273 bits (698), Expect = 2e-76, Method: Composition-based stats.
Identities = 93/331 (28%), Positives = 148/331 (45%), Gaps = 23/331 (7%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
E PS ++ L Q V + D V + L +G G+F
Sbjct 513 YRLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVPKDKWVLNHEDLVLGEQIGRGNF 572
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968
G+V N +VAVK+ + P ++ + QE IL+ H +I++ G C
Sbjct 573 GEVFSGRLRADN----TLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQ 628
Query 969 QGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
+ + + +VME V G +L + + LL GM YL ++ IHRDLAA
Sbjct 629 K--QPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAA 686
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RN L+ ++KI DFG+++ +G Y PV W APE L ++ SDVWS
Sbjct 687 RNCLVTEKNVLKISDFGMSREEADGV-YAASGGLRQVPVKWTAPEALNYGRYSSESDVWS 745
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
FG+ L+E + L ++ + E +E+G RLP P+ CP V+
Sbjct 746 FGILLWETFS--------------LGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFR 791
Query 1147 LMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
LM+ CW E RP+F + L+++ ++++
Sbjct 792 LMEQCWAYEPGQRPSFSTIYQELQSIRKRHR 822
>sp|P50545|HCK_RAT Tyrosine-protein kinase HCK OS=Rattus norvegicus
OX=10116 GN=Hck PE=1 SV=4
Length=524
Score = 281 bits (720), Expect = 4e-82, Method: Composition-based stats.
Identities = 82/447 (18%), Positives = 150/447 (34%), Gaps = 71/447 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502
+ + + L G ++I S + L+V +
Sbjct 138 ETEEWFFKGISRKDAERHLLAPGNMLGSFMIRDSETTKGSYSLSVRDFDP----QHGDTV 193
Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562
+ + I D +F S++EL + C L C+
Sbjct 194 KHYKIRTLDSGGFYISPRSTFSSLQELVVHYKKGK---DGLCQKLSVPCV---------- 240
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
SP+ + + ++ + LG G V+
Sbjct 241 -------SPKPQKPWEKDAWEIPRESLQMEKKLGAGQFGEVWMAT--------------- 278
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
+ +V +K + P + AF A+LM + H L +H V +
Sbjct 279 ----------YNKHTKVAVKTMKPGSMSV-EAFLAEANLMKTLQHDKLVKLHAVVSQ-EP 326
Query 683 NIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
+VTE++ G L +L+ E G P+ + + Q++ ++++E +N +H ++ NIL
Sbjct 327 IFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQISEGMAFIEQRNYIHRDLRAANIL 386
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMD 796
++ S K++D G+ E I W APE + G S + D
Sbjct 387 VS-------ASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFG--SFTIKSD 437
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854
W FG L+EI G P S E + +R+ P+ +L ++ +C P
Sbjct 438 VWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNCPEELYSIMIRCWKNRPE 497
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVN 881
+RP+F I L +
Sbjct 498 ERPTFEYIQSVLDDFYTATESQYQQQP 524
Score = 279 bits (714), Expect = 2e-81, Method: Composition-based stats.
Identities = 96/293 (33%), Positives = 146/293 (50%), Gaps = 29/293 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ L+ + LG G FG+V + Y N T VAVK +K G + E +
Sbjct 253 WEIPRESLQMEKKLGAGQFGEVWMATY---NKHT--KVAVKTMKP--GSMSVEAFLAEAN 305
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQ 1006
+++TL H+ ++K ++ + +V E++ GSL D+L L +L+ F+ Q
Sbjct 306 LMKTLQHDKLVKLHAVV---SQEPIFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQ 362
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I EGMA++ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+
Sbjct 363 ISEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNE--YTAREGAKFPIK 420
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE + F SDVWSFG+ L E++T+ I M+ +
Sbjct 421 WTAPEAINFGSFTIKSDVWSFGILLMEIVTYGR--------------IPYPGMSNPEVIR 466
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
LE G R+PRPD CP E+Y +M CW+ RPTFE + +L + + Q
Sbjct 467 ALEHGYRMPRPDNCPEELYSIMIRCWKNRPEERPTFEYIQSVLDDFYTATESQ 519
>sp|P42682|TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus musculus
OX=10090 GN=Txk PE=1 SV=1
Length=527
Score = 281 bits (719), Expect = 6e-82, Method: Composition-based stats.
Identities = 93/435 (21%), Positives = 166/435 (38%), Gaps = 68/435 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRPE--DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLR-- 501
I + H + + LR E +G +++ S H ++V R + +
Sbjct 146 EIYEWYHKNITRNQTERLLRQEAKEGAFIVRDS-RHLGSYTISVFTR-----ARRHTQSS 199
Query 502 LRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNL 561
++ + I++ D FPSV EL Q A LR
Sbjct 200 IKHYQIKKNDSGQWYITERHLFPSVPELIQYHQYN---AAGLISRLRYP----------- 245
Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
I P T S +D E+ + +G G V+ G R
Sbjct 246 -IGLLGSCLPATSGFSY-EKWEIDPSELAFVKEIGSGQFGVVHLGEWRA----------- 292
Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
+ V +K ++ F E A +M ++SH+ L ++GVC++
Sbjct 293 --------------HIPVAIKAINEGSMS-EEDFIEEAKVMMKLSHSRLVQLYGVCIQQK 337
Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
+VTE++E+G L +LR +G + A + + Q + ++YLE +H ++ RN L
Sbjct 338 PLYIVTEFMENGCLLDYLRERKGQLQKALLLSMCQDICEGMAYLERSCYIHRDLAARNCL 397
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMD 796
++ ++ +K+SD G+ L E + W PE N S+ D
Sbjct 398 VS-------SACVVKISDFGMARYVLDDEYISSSGAKFPVKWCPPEVFH--FNKYSSKSD 448
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854
W FG + E+ +G+ P +++S + + RL P + + + C P
Sbjct 449 VWSFGVLMWEVFTEGKMPFENKSNLQVVEAISQGFRLYRPHLAPMTIYRVMYSCWHESPK 508
Query 855 QRPSFRTILRDLTRL 869
RP+F +L+ LT +
Sbjct 509 GRPTFAELLQVLTEI 523
Score = 263 bits (672), Expect = 1e-75, Method: Composition-based stats.
Identities = 94/299 (31%), Positives = 136/299 (45%), Gaps = 27/299 (9%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ + L ++++G G FG V L + VA+KA+ G
Sbjct 252 CLPATSGFSYEKWEIDPSELAFVKEIGSGQFGVVHLGEWRAH-----IPVAIKAINE--G 304
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL 997
+ +E ++ L H +++ G C Q K L +V E++ G L DYL L
Sbjct 305 SMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQQ--KPLYIVTEFMENGCLLDYLRERKGQL 362
Query 998 AQ--LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ LL Q ICEGMAYL YIHRDLAARN L+ + +VKI DFG+A+ V + Y
Sbjct 363 QKALLLSMCQDICEGMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARYVLDDE--Y 420
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
PV W PE K+ SDVWSFGV ++E+ T +
Sbjct 421 ISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGK--------------MP 466
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ L++ E + +G RL RP P +Y +M +CW RPTF L+ +L + E
Sbjct 467 FENKSNLQVVEAISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVLTEIAE 525
>sp|Q91736|EPB1B_XENLA Ephrin type-B receptor 1-B (Fragment) OS=Xenopus
laevis OX=8355 GN=ephb1-b PE=1 SV=1
Length=902
Score = 291 bits (744), Expect = 6e-82, Method: Composition-based stats.
Identities = 79/308 (26%), Positives = 146/308 (47%), Gaps = 21/308 (7%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
++ + ++ ++K +G G FG+V + VA
Sbjct 509 MKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPSKRE-ISVA 567
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LKA + R + E I+ H +II+ +G + + ++ E++ G+L
Sbjct 568 IKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGALDS 625
Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
+L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++
Sbjct 626 FLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 685
Query 1047 AVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
+ + Y G PV W APE ++ KF ASDVWS+G+ ++E++++ +
Sbjct 686 YLQDDTSDPTYTSSLGGKIPVRWTAPEAIRYRKFTSASDVWSYGIVMWEVMSYGER---- 741
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
M+ + +E+ RLP P CP ++ LM +CW+ + + RP F
Sbjct 742 ----------PYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFGE 791
Query 1165 LIPILKTV 1172
++ L +
Sbjct 792 IVNTLDKM 799
Score = 277 bits (709), Expect = 3e-77, Method: Composition-based stats.
Identities = 76/355 (21%), Positives = 136/355 (38%), Gaps = 42/355 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G VY+GRL++ +E+ V +
Sbjct 530 KEIDVSFVKIEEVIGAGEFGEVYKGRLKLPSK---------------------REISVAI 568
Query 642 KVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L F AS+M Q H ++ + GV + +++TE++E+G LD +LR
Sbjct 569 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 628
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD
Sbjct 629 QNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 681
Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ +IP W APE + ++A D W +G + E+ G
Sbjct 682 GLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIR--YRKFTSASDVWSYGIVMWEVMSYG 739
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P S + + ++ +RLP P CP L L C + RP F I+ L ++
Sbjct 740 ERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFGEIVNTLDKM 799
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
+ + + S P + + + + Y +G
Sbjct 800 IRNPASLKTVATIPAVPSQPLLDRSIPDISAFTSVDDWLSAIKMGQYRDNFLSSG 854
>sp|Q91694|EPA4B_XENLA Ephrin type-A receptor 4-B OS=Xenopus laevis
OX=8355 GN=epha4-b PE=2 SV=1
Length=985
Score = 292 bits (747), Expect = 9e-82, Method: Composition-based stats.
Identities = 83/331 (25%), Positives = 148/331 (45%), Gaps = 19/331 (6%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
+ S+ + + ++ + + +K + +
Sbjct 567 VISRRRSKYSKAKQEADEEKHLNQGVKTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVI 626
Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963
G G FG+V VA+K LKA + R + E I+ H +II +
Sbjct 627 GVGEFGEVCSGRLKVPGKRE-IYVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLE 685
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G K + ++ EY+ GSL +L ++ + QL+ + I GM YL Y+H
Sbjct 686 GVVTKC--KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVH 743
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RDLAARN+L++++ + K+ DFG+++ + + E G P+ W APE + KF A
Sbjct 744 RDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSA 803
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
SDVWS+G+ ++E++++ + M+ + + +E G RLP P CP
Sbjct 804 SDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVIKAIEEGYRLPPPMDCP 849
Query 1142 CEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
++ LM +CW+ + S RP F ++ +L +
Sbjct 850 IALHQLMLDCWQKDRSDRPKFGQIVSMLDKL 880
Score = 269 bits (688), Expect = 6e-74, Method: Composition-based stats.
Identities = 76/302 (25%), Positives = 124/302 (41%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D I +G G V GRL+V G +E+ V +
Sbjct 613 KEIDASCIKIEKVIGVGEFGEVCSGRLKVPGK---------------------REIYVAI 651
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + D F AS+M Q H ++ + GV + +++TEY+E+G LD +LR
Sbjct 652 KTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLR 711
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + + S + YL + + VH ++ RNIL+ ++ K+SD
Sbjct 712 KNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVN-------SNLVCKVSDF 764
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E I W APE + ++A D W +G + E+ GE
Sbjct 765 GMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER 822
Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + + +RLP P CP L L C + + RP F I+ L +L
Sbjct 823 PYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKDRSDRPKFGQIVSMLDKLIR 882
Query 872 HN 873
+
Sbjct 883 NP 884
>sp|Q91845|EPA4A_XENLA Ephrin type-A receptor 4-A OS=Xenopus laevis
OX=8355 GN=epha4-a PE=2 SV=1
Length=986
Score = 291 bits (746), Expect = 1e-81, Method: Composition-based stats.
Identities = 84/331 (25%), Positives = 148/331 (45%), Gaps = 19/331 (6%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
+ S+ + + ++ + + +K + +
Sbjct 567 VISRRRSKYSKAKQEADEEKHLNQGVKTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVI 626
Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963
G G FG+V VA+K LKA + R + E I+ H +II +
Sbjct 627 GVGEFGEVCSGRLKVPGKRE-IYVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLE 685
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G K + ++ EY+ GSL +L ++ + QL+ + I GM YL Y+H
Sbjct 686 GVVTKC--KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGILRGIGSGMKYLSDMSYVH 743
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RDLAARN+L++++ + K+ DFG+++ + + E G P+ W APE + KF A
Sbjct 744 RDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSA 803
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
SDVWS+G+ ++E++++ + M+ + + +E G RLP P CP
Sbjct 804 SDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVIKAIEEGYRLPPPMDCP 849
Query 1142 CEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
++ LM +CW+ E S RP F ++ +L +
Sbjct 850 IALHQLMLDCWQKERSDRPKFGQIVSMLDKL 880
Score = 270 bits (689), Expect = 5e-74, Method: Composition-based stats.
Identities = 77/302 (25%), Positives = 124/302 (41%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D I +G G V GRL+V G +E+ V +
Sbjct 613 KEIDASCIKIEKVIGVGEFGEVCSGRLKVPGK---------------------REIYVAI 651
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + D F AS+M Q H ++ + GV + +++TEY+E+G LD +LR
Sbjct 652 KTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLR 711
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + + S + YL + + VH ++ RNIL+ ++ K+SD
Sbjct 712 KNDGRFTVIQLVGILRGIGSGMKYLSDMSYVHRDLAARNILVN-------SNLVCKVSDF 764
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E I W APE + ++A D W +G + E+ GE
Sbjct 765 GMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER 822
Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + + +RLP P CP L L C E + RP F I+ L +L
Sbjct 823 PYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVSMLDKLIR 882
Query 872 HN 873
+
Sbjct 883 NP 884
>sp|P54763|EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus musculus
OX=10090 GN=Ephb2 PE=1 SV=3
Length=986
Score = 291 bits (746), Expect = 1e-81, Method: Composition-based stats.
Identities = 81/325 (25%), Positives = 147/325 (45%), Gaps = 21/325 (6%)
Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911
E T + T ++ + ++ +K + +G G FG+V
Sbjct 576 EYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEV 635
Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
VA+K LK+ + R + E I+ H ++I +G
Sbjct 636 CSGHLKLPGKRE-IFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKST- 693
Query 972 KSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029
+ ++ E++ GSL +L ++ + QL+ + I GM YL +Y+HRDLAARN+
Sbjct 694 -PVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNI 752
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
L++++ + K+ DFGL++ + + Y G P+ W APE ++ KF ASDVWS+
Sbjct 753 LVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSY 812
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
G+ ++E++++ + MT + +E+ RLP P CP ++ L
Sbjct 813 GIVMWEVMSYGER--------------PYWDMTNQDVINAIEQDYRLPPPMDCPSALHQL 858
Query 1148 MKNCWETEASFRPTFENLIPILKTV 1172
M +CW+ + + RP F ++ L +
Sbjct 859 MLDCWQKDRNHRPKFGQIVNTLDKM 883
Score = 268 bits (685), Expect = 1e-73, Method: Composition-based stats.
Identities = 70/304 (23%), Positives = 125/304 (41%), Gaps = 42/304 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G V G L++ G +E+ V +
Sbjct 614 KEIDISCVKIEQVIGAGEFGEVCSGHLKLPGK---------------------REIFVAI 652
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + +++TE++E+G LD +LR
Sbjct 653 KTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLR 712
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL + N VH ++ RNIL+ ++ K+SD
Sbjct 713 QNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVN-------SNLVCKVSDF 765
Query 761 GVGL---GALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ S I W APE + ++A D W +G + E+ G
Sbjct 766 GLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYG 823
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P + + + ++ +RLP P CP L L C + RP F I+ L ++
Sbjct 824 ERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 883
Query 870 QPHN 873
+
Sbjct 884 IRNP 887
>sp|P21802|FGFR2_HUMAN Fibroblast growth factor receptor 2 OS=Homo
sapiens OX=9606 GN=FGFR2 PE=1 SV=1
Length=821
Score = 288 bits (737), Expect = 1e-81, Method: Composition-based stats.
Identities = 106/343 (31%), Positives = 159/343 (46%), Gaps = 53/343 (15%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCG 937
+ P F + L + LGEG FG+V + + + VAVK LK D
Sbjct 465 EYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDAT 524
Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990
+ S E+++++ + H++II G C G L +++EY G+LR+YL
Sbjct 525 EKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPP 582
Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P + L+ Q+ GM YL +Q IHRDLAARNVL+ + ++KI
Sbjct 583 GMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKI 642
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV ++E+ T
Sbjct 643 ADFGLARDI-NNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT--- 698
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L G + V L +LL+ G R+ +P C E+Y +M++CW S R
Sbjct 699 -----------LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQR 747
Query 1160 PTFENLIPILKTV---------------HEKYQGQAPSVFSVC 1187
PTF+ L+ L + E+Y P S C
Sbjct 748 PTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSC 790
Score = 234 bits (596), Expect = 7e-63, Method: Composition-based stats.
Identities = 65/323 (20%), Positives = 117/323 (36%), Gaps = 51/323 (16%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
L + + ++T LG+G V + E +
Sbjct 464 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQV-----------------VMAEAVGIDKD 506
Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689
+ + V +K+L + L +M + H ++ + G C + ++ EY
Sbjct 507 KPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 566
Query 690 VEHGPLDVWLRRER----------GHVPMAW-----KMVVAQQLASALSYLENKNLVHGN 734
G L +LR R VP + QLA + YL ++ +H +
Sbjct 567 ASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD 626
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788
+ RN+L+ + +K++D G+ ++ R+P W+APE L
Sbjct 627 LAARNVLVTENNV-------MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRV 679
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846
+ D W FG + EI G +P E + HR+ P +L +
Sbjct 680 --YTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMR 737
Query 847 QCLTYEPTQRPSFRTILRDLTRL 869
C P+QRP+F+ ++ DL R+
Sbjct 738 DCWHAVPSQRPTFKQLVEDLDRI 760
>sp|Q1KL86|EPHA2_MACFA Ephrin type-A receptor 2 OS=Macaca fascicularis
OX=9541 GN=EPHA2 PE=2 SV=1
Length=976
Score = 291 bits (746), Expect = 1e-81, Method: Composition-based stats.
Identities = 87/329 (26%), Positives = 153/329 (47%), Gaps = 18/329 (5%)
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
+ L + + + L L+ + + T H + + + +G
Sbjct 562 RKNLRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGA 621
Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGC 965
G FG+V ++ VA+K LKA + R + E I+ H +II+ +G
Sbjct 622 GEFGEVYKGTLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGV 681
Query 966 CEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRD 1023
K + ++ E++ G+L +L + QL+ + I GM YL +Y+HRD
Sbjct 682 ISKY--KPMMIITEFMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRD 739
Query 1024 LAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASD 1083
LAARN+L++++ + K+ DFGL++ + + E G P+ W APE + KF ASD
Sbjct 740 LAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASD 799
Query 1084 VWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE 1143
VWSFG+ ++E++T+ + +++ + + + G RLP P CP
Sbjct 800 VWSFGIVMWEVMTYGER--------------PYWELSNHEVMKAINDGFRLPTPMDCPSA 845
Query 1144 VYHLMKNCWETEASFRPTFENLIPILKTV 1172
+Y LM CW+ E + RP F +++ IL +
Sbjct 846 IYQLMMQCWQQERARRPKFADIVSILDKL 874
Score = 266 bits (681), Expect = 5e-73, Method: Composition-based stats.
Identities = 75/299 (25%), Positives = 122/299 (41%), Gaps = 39/299 (13%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
+ +T+ +G G VY+G L+ +E+ V
Sbjct 605 TTEIHPSCVTRQKVIGAGEFGEVYKGTLKTSSG--------------------KKEVPVA 644
Query 641 LKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+K L + + F A +M Q SH ++ + GV + +++TE++E+G LD +L
Sbjct 645 IKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEFMENGALDKFL 704
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R + G + + + + +A+ + YL N N VH ++ RNIL+ ++ K+SD
Sbjct 705 REKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVN-------SNLVCKVSD 757
Query 760 PGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
G+ E I W APE + ++A D W FG + E+ GE
Sbjct 758 FGLSRVLEDDPEATYTTSGGKIPIRWTAPEAIS--YRKFTSASDVWSFGIVMWEVMTYGE 815
Query 813 APLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
P S E RLP CP + L QC E +RP F I+ L +L
Sbjct 816 RPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKL 874
>sp|P21804|FGFR1_CHICK Fibroblast growth factor receptor 1 OS=Gallus
gallus OX=9031 GN=FGFR1 PE=2 SV=1
Length=819
Score = 288 bits (737), Expect = 1e-81, Method: Composition-based stats.
Identities = 103/313 (33%), Positives = 153/313 (49%), Gaps = 38/313 (12%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---EMVAVKALKADCG 937
+ P + L + LGEG FG+V L + VAVK LK+D
Sbjct 460 EYELPEDPRWELPRDRLILGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDAT 519
Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990
+ S E+++++ + H++II G C G L +++EY G+LR+YL
Sbjct 520 EKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLQARRPP 577
Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI
Sbjct 578 GMEYCYNPTRIPEEQLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKI 637
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T
Sbjct 638 ADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--- 693
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L G + V L +LL+ G R+ +P C E+Y +M++CW S R
Sbjct 694 -----------LGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQR 742
Query 1160 PTFENLIPILKTV 1172
PTF+ L+ L +
Sbjct 743 PTFKQLVEDLDRI 755
Score = 235 bits (600), Expect = 2e-63, Method: Composition-based stats.
Identities = 63/332 (19%), Positives = 116/332 (35%), Gaps = 51/332 (15%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
L + + + + LG+G V + E +
Sbjct 459 SEYELPEDPRWELPRDRLILGKPLGEGCFGQV-----------------VLAEAIGLDKD 501
Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689
+ +V +K+L + L +M + H ++ + G C + ++ EY
Sbjct 502 KPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 561
Query 690 VEHGPLDVWLRRERG---------------HVPMAWKMVVAQQLASALSYLENKNLVHGN 734
G L +L+ R + + A Q+A + YL +K +H +
Sbjct 562 ASKGNLREYLQARRPPGMEYCYNPTRIPEEQLSFKDLVSCAYQVARGMEYLASKKCIHRD 621
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788
+ RN+L+ + +K++D G+ ++ R+P W+APE L
Sbjct 622 LAARNVLVTEDNV-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRI 674
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846
+ D W FG L EI G +P E + HR+ P +L +
Sbjct 675 --YTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMR 732
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
C P+QRP+F+ ++ DL R+
Sbjct 733 DCWHAVPSQRPTFKQLVEDLDRIVAMTSNQEY 764
>sp|P18461|FGFR2_CHICK Fibroblast growth factor receptor 2 OS=Gallus
gallus OX=9031 GN=FGFR2 PE=2 SV=1
Length=823
Score = 288 bits (737), Expect = 2e-81, Method: Composition-based stats.
Identities = 106/343 (31%), Positives = 160/343 (47%), Gaps = 53/343 (15%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCG 937
+ P F + L + LGEG FG+V + + + VAVK LK D
Sbjct 467 EYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKEAVTVAVKMLKDDAT 526
Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990
+ S E+++++ + H++II G C G L +++EY G+LR+YL
Sbjct 527 EKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPP 584
Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P + L+ Q+ GM YL +Q IHRDLAARNVL+ + ++KI
Sbjct 585 GMEYSFDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKI 644
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV ++E+ T
Sbjct 645 ADFGLARDI-NNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT--- 700
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L G + V L +LL+ G R+ +P C E+Y +M++CW+ S R
Sbjct 701 -----------LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWQAVPSQR 749
Query 1160 PTFENLIPILKTV---------------HEKYQGQAPSVFSVC 1187
PTF+ L+ L + E+Y P S C
Sbjct 750 PTFKQLVEDLDRILTLTTNEEYLDLSGPLEQYSPSYPDTRSSC 792
Score = 233 bits (594), Expect = 1e-62, Method: Composition-based stats.
Identities = 65/323 (20%), Positives = 117/323 (36%), Gaps = 51/323 (16%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
L + + ++T LG+G V + E +
Sbjct 466 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQV-----------------VMAEAVGIDKD 508
Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689
+ + V +K+L + L +M + H ++ + G C + ++ EY
Sbjct 509 RPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 568
Query 690 VEHGPLDVWLRRER----------GHVPMAW-----KMVVAQQLASALSYLENKNLVHGN 734
G L +LR R VP + QLA + YL ++ +H +
Sbjct 569 ASKGNLREYLRARRPPGMEYSFDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD 628
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788
+ RN+L+ + +K++D G+ ++ R+P W+APE L
Sbjct 629 LAARNVLVTENNV-------MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRV 681
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846
+ D W FG + EI G +P E + HR+ P +L +
Sbjct 682 --YTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMR 739
Query 847 QCLTYEPTQRPSFRTILRDLTRL 869
C P+QRP+F+ ++ DL R+
Sbjct 740 DCWQAVPSQRPTFKQLVEDLDRI 762
>sp|Q61772|EPHA7_MOUSE Ephrin type-A receptor 7 OS=Mus musculus
OX=10090 GN=Epha7 PE=1 SV=2
Length=998
Score = 291 bits (746), Expect = 2e-81, Method: Composition-based stats.
Identities = 83/313 (27%), Positives = 145/313 (46%), Gaps = 19/313 (6%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
+ + + + +K R +G G FG+V
Sbjct 598 FHFKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGK 657
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VA+K LK + R + E I+ H +++ +G K + +V+E++
Sbjct 658 RD-VAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRG--KPVMIVIEFM 714
Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
G+L +L +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+
Sbjct 715 ENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKV 774
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGL++ + + E G PV W APE ++ KF ASDVWS+G+ ++E++++ +
Sbjct 775 SDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGE 834
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
M+ + + +E G RLP P CP ++ LM +CW+ + + R
Sbjct 835 R--------------PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKDRAER 880
Query 1160 PTFENLIPILKTV 1172
P FE ++ IL +
Sbjct 881 PKFEQIVGILDKM 893
Score = 270 bits (689), Expect = 5e-74, Method: Composition-based stats.
Identities = 72/302 (24%), Positives = 124/302 (41%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D I +G G V GRL++ G +++ V +
Sbjct 626 KELDASCIKIERVIGAGEFGEVCSGRLKLPGK---------------------RDVAVAI 664
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV RG ++V E++E+G LD +LR
Sbjct 665 KTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLR 724
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL + VH ++ RNIL+ ++ K+SD
Sbjct 725 KHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVN-------SNLVCKVSDF 777
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E V + W APE + ++A D W +G + E+ GE
Sbjct 778 GLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYGER 835
Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + + +RLP CP L L C + +RP F I+ L ++
Sbjct 836 PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKDRAERPKFEQIVGILDKMIR 895
Query 872 HN 873
+
Sbjct 896 NP 897
>sp|O42422|EPHA7_CHICK Ephrin type-A receptor 7 OS=Gallus gallus
OX=9031 GN=EPHA7 PE=2 SV=1
Length=993
Score = 291 bits (744), Expect = 3e-81, Method: Composition-based stats.
Identities = 85/313 (27%), Positives = 144/313 (46%), Gaps = 19/313 (6%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
+ + + + +K R +G G FG+V
Sbjct 593 FHFKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGK 652
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VA+K LK + R + E I+ H +++ +G K + +V+EY+
Sbjct 653 RD-VAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRG--KPVMIVIEYM 709
Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
G+L +L +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+
Sbjct 710 ENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKV 769
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGL++ + + E G PV W APE ++ KF ASDVWS+G+ ++E++++ +
Sbjct 770 SDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGE 829
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
M+ + + +E G RLP P CP ++ LM +CW+ E R
Sbjct 830 R--------------PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERGER 875
Query 1160 PTFENLIPILKTV 1172
P FE ++ IL +
Sbjct 876 PKFEQIVGILDKM 888
Score = 270 bits (690), Expect = 4e-74, Method: Composition-based stats.
Identities = 74/302 (25%), Positives = 124/302 (41%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D I +G G V GRL++ G +++ V +
Sbjct 621 KELDASCIKIERVIGAGEFGEVCSGRLKLPGK---------------------RDVAVAI 659
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV RG ++V EY+E+G LD +LR
Sbjct 660 KTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEYMENGALDAFLR 719
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL + VH ++ RNIL+ ++ K+SD
Sbjct 720 KHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVN-------SNLVCKVSDF 772
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E V + W APE + ++A D W +G + E+ GE
Sbjct 773 GLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYGER 830
Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + + +RLP CP L L C E +RP F I+ L ++
Sbjct 831 PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERGERPKFEQIVGILDKMIR 890
Query 872 HN 873
+
Sbjct 891 NP 892
>sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens
OX=9606 GN=EPHB2 PE=1 SV=5
Length=1055
Score = 291 bits (746), Expect = 3e-81, Method: Composition-based stats.
Identities = 81/325 (25%), Positives = 147/325 (45%), Gaps = 21/325 (6%)
Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911
E T + T ++ + ++ +K + +G G FG+V
Sbjct 576 EYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEV 635
Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
VA+K LK+ + R + E I+ H ++I +G
Sbjct 636 CSGHLKLPGKRE-IFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKST- 693
Query 972 KSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029
+ ++ E++ GSL +L ++ + QL+ + I GM YL +Y+HRDLAARN+
Sbjct 694 -PVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNI 752
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
L++++ + K+ DFGL++ + + Y G P+ W APE ++ KF ASDVWS+
Sbjct 753 LVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSY 812
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
G+ ++E++++ + MT + +E+ RLP P CP ++ L
Sbjct 813 GIVMWEVMSYGER--------------PYWDMTNQDVINAIEQDYRLPPPMDCPSALHQL 858
Query 1148 MKNCWETEASFRPTFENLIPILKTV 1172
M +CW+ + + RP F ++ L +
Sbjct 859 MLDCWQKDRNHRPKFGQIVNTLDKM 883
Score = 268 bits (685), Expect = 3e-73, Method: Composition-based stats.
Identities = 70/304 (23%), Positives = 125/304 (41%), Gaps = 42/304 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G V G L++ G +E+ V +
Sbjct 614 KEIDISCVKIEQVIGAGEFGEVCSGHLKLPGK---------------------REIFVAI 652
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + +++TE++E+G LD +LR
Sbjct 653 KTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLR 712
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL + N VH ++ RNIL+ ++ K+SD
Sbjct 713 QNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVN-------SNLVCKVSDF 765
Query 761 GVGL---GALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ S I W APE + ++A D W +G + E+ G
Sbjct 766 GLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYG 823
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P + + + ++ +RLP P CP L L C + RP F I+ L ++
Sbjct 824 ERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 883
Query 870 QPHN 873
+
Sbjct 884 IRNP 887
>sp|P54759|EPHA7_RAT Ephrin type-A receptor 7 OS=Rattus norvegicus
OX=10116 GN=Epha7 PE=1 SV=1
Length=998
Score = 290 bits (743), Expect = 4e-81, Method: Composition-based stats.
Identities = 84/313 (27%), Positives = 145/313 (46%), Gaps = 19/313 (6%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
+ + + + +K R +G G FG+V
Sbjct 598 FHFKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGK 657
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VA+K LK + R + E I+ H +++ +G K + +V+E++
Sbjct 658 RD-VAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRG--KPVMIVIEFM 714
Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
G+L +L +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+
Sbjct 715 ENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKV 774
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGL++ + + E G PV W APE ++ KF ASDVWS+G+ ++E++++ +
Sbjct 775 SDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGE 834
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
M+ + + +E G RLP P CP ++ LM +CW+ E + R
Sbjct 835 R--------------PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAER 880
Query 1160 PTFENLIPILKTV 1172
P FE ++ IL +
Sbjct 881 PKFEQIVGILDKM 893
Score = 269 bits (688), Expect = 7e-74, Method: Composition-based stats.
Identities = 73/302 (24%), Positives = 124/302 (41%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D I +G G V GRL++ G +++ V +
Sbjct 626 KELDASCIKIERVIGAGEFGEVCSGRLKLPGK---------------------RDVAVAI 664
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV RG ++V E++E+G LD +LR
Sbjct 665 KTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLR 724
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL + VH ++ RNIL+ ++ K+SD
Sbjct 725 KHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVN-------SNLVCKVSDF 777
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E V + W APE + ++A D W +G + E+ GE
Sbjct 778 GLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYGER 835
Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + + +RLP CP L L C E +RP F I+ L ++
Sbjct 836 PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIR 895
Query 872 HN 873
+
Sbjct 896 NP 897
>sp|Q15375|EPHA7_HUMAN Ephrin type-A receptor 7 OS=Homo sapiens
OX=9606 GN=EPHA7 PE=1 SV=3
Length=998
Score = 290 bits (743), Expect = 4e-81, Method: Composition-based stats.
Identities = 84/313 (27%), Positives = 145/313 (46%), Gaps = 19/313 (6%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
+ + + + +K R +G G FG+V
Sbjct 598 FHFKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGK 657
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VA+K LK + R + E I+ H +++ +G K + +V+E++
Sbjct 658 RD-VAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRG--KPVMIVIEFM 714
Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
G+L +L +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+
Sbjct 715 ENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKV 774
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGL++ + + E G PV W APE ++ KF ASDVWS+G+ ++E++++ +
Sbjct 775 SDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGE 834
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
M+ + + +E G RLP P CP ++ LM +CW+ E + R
Sbjct 835 R--------------PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAER 880
Query 1160 PTFENLIPILKTV 1172
P FE ++ IL +
Sbjct 881 PKFEQIVGILDKM 893
Score = 269 bits (688), Expect = 7e-74, Method: Composition-based stats.
Identities = 73/302 (24%), Positives = 124/302 (41%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D I +G G V GRL++ G +++ V +
Sbjct 626 KELDASCIKIERVIGAGEFGEVCSGRLKLPGK---------------------RDVAVAI 664
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV RG ++V E++E+G LD +LR
Sbjct 665 KTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLR 724
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL + VH ++ RNIL+ ++ K+SD
Sbjct 725 KHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVN-------SNLVCKVSDF 777
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E V + W APE + ++A D W +G + E+ GE
Sbjct 778 GLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYGER 835
Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + + +RLP CP L L C E +RP F I+ L ++
Sbjct 836 PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIR 895
Query 872 HN 873
+
Sbjct 896 NP 897
>sp|P28693|EPHB2_CHICK Ephrin type-B receptor 2 OS=Gallus gallus
OX=9031 GN=EPHB2 PE=1 SV=3
Length=1004
Score = 290 bits (743), Expect = 4e-81, Method: Composition-based stats.
Identities = 78/315 (25%), Positives = 144/315 (46%), Gaps = 21/315 (7%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
+ ++ + ++ +K + +G G FG+V
Sbjct 604 LFVMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGK 663
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
VA+K LK+ + R + E I+ H ++I +G + ++ E++
Sbjct 664 RE-IFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSS--PVMIITEFM 720
Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
GSL +L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+
Sbjct 721 ENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKV 780
Query 1040 GDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
DFGL++ + + Y G P+ W APE ++ KF ASDVWS+G+ ++E++++
Sbjct 781 SDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSY 840
Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157
+ MT + +E+ RLP P CP ++ LM +CW+ + +
Sbjct 841 GER--------------PYWDMTNQDVINAIEQDYRLPPPMDCPNALHQLMLDCWQKDRN 886
Query 1158 FRPTFENLIPILKTV 1172
RP F ++ L +
Sbjct 887 HRPKFGQIVNTLDKM 901
Score = 269 bits (687), Expect = 9e-74, Method: Composition-based stats.
Identities = 70/304 (23%), Positives = 125/304 (41%), Gaps = 42/304 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G V G L++ G +E+ V +
Sbjct 632 KEIDISCVKIEQVIGAGEFGEVCSGHLKLPGK---------------------REIFVAI 670
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + +++TE++E+G LD +LR
Sbjct 671 KTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMIITEFMENGSLDSFLR 730
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL + N VH ++ RNIL+ ++ K+SD
Sbjct 731 QNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVN-------SNLVCKVSDF 783
Query 761 GVGL---GALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ S I W APE + ++A D W +G + E+ G
Sbjct 784 GLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYG 841
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P + + + ++ +RLP P CP L L C + RP F I+ L ++
Sbjct 842 ERPYWDMTNQDVINAIEQDYRLPPPMDCPNALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 901
Query 870 QPHN 873
+
Sbjct 902 IRNP 905
>sp|P16092|FGFR1_MOUSE Fibroblast growth factor receptor 1 OS=Mus
musculus OX=10090 GN=Fgfr1 PE=1 SV=2
Length=822
Score = 287 bits (734), Expect = 4e-81, Method: Composition-based stats.
Identities = 113/398 (28%), Positives = 179/398 (45%), Gaps = 41/398 (10%)
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
+ GA L+ + +S ++K F+ + L + ++ + +
Sbjct 379 IYCTGAFLISCMLGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVT--VSADSSAS 436
Query 857 PSFRTILRDLTRLQPHNLAD-VLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915
+ +L +RL + P + L + LGEG FG+V L
Sbjct 437 MNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAE 496
Query 916 YDPTNDGTG---EMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGE 971
+ VAVK LK+D + S E+++++ + H++II G C G
Sbjct 497 AIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG- 555
Query 972 KSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQLLLFAQQICEGMAYL 1014
L +++EY G+LR+YL P + L+ A Q+ GM YL
Sbjct 556 -PLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYL 614
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+ +G PV W APE L
Sbjct 615 ASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALF 673
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ + + SDVWSFGV L+E+ T L G + V L +LL+ G R+
Sbjct 674 DRIYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGVPVEELFKLLKEGHRM 719
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+P C E+Y +M++CW S RPTF+ L+ L +
Sbjct 720 DKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 757
Score = 235 bits (600), Expect = 2e-63, Method: Composition-based stats.
Identities = 66/348 (19%), Positives = 123/348 (35%), Gaps = 60/348 (17%)
Query 556 GETSNLIIMRGARASPR---------TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606
S ++++R +R S L + + + + LG+G V
Sbjct 436 SMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQV--- 492
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV 665
+ E + + +V +K+L + L +M +
Sbjct 493 --------------VLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMI 538
Query 666 -SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---------------RRERGHVPMA 709
H ++ + G C + ++ EY G L +L +
Sbjct 539 GKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSK 598
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA--- 766
+ A Q+A + YL +K +H ++ RN+L+ + +K++D G+
Sbjct 599 DLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNV-------MKIADFGLARDIHHI 651
Query 767 -LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
++ R+P W+APE L + D W FG L EI G +P E
Sbjct 652 DYYKKTTNGRLPVKWMAPEALFDRI--YTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEEL 709
Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ HR+ P +L + C P+QRP+F+ ++ DL R+
Sbjct 710 FKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 757
>sp|Q03137|EPHA4_MOUSE Ephrin type-A receptor 4 OS=Mus musculus
OX=10090 GN=Epha4 PE=1 SV=2
Length=986
Score = 290 bits (743), Expect = 4e-81, Method: Composition-based stats.
Identities = 86/332 (26%), Positives = 151/332 (45%), Gaps = 21/332 (6%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
+ S+ + + ++ + + +K + +
Sbjct 568 VISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVI 627
Query 904 GEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
G G FG+V G E+ VA+K LKA + R + E I+ H +II
Sbjct 628 GVGEFGEVCSGRLKV--PGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHL 685
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+G K + ++ EY+ GSL +L ++ + QL+ + I GM YL Y+
Sbjct 686 EGVVTKC--KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYV 743
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARN+L++++ + K+ DFG+++ + + E G P+ W APE + KF
Sbjct 744 HRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTS 803
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
ASDVWS+G+ ++E++++ + M+ + + +E G RLP P C
Sbjct 804 ASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVIKAIEEGYRLPPPMDC 849
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P ++ LM +CW+ E S RP F ++ +L +
Sbjct 850 PIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881
Score = 269 bits (687), Expect = 9e-74, Method: Composition-based stats.
Identities = 77/302 (25%), Positives = 124/302 (41%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D I +G G V GRL+V G +E+ V +
Sbjct 614 KEIDASCIKIEKVIGVGEFGEVCSGRLKVPGK---------------------REICVAI 652
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + D F AS+M Q H ++ + GV + +++TEY+E+G LD +LR
Sbjct 653 KTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLR 712
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + + S + YL + + VH ++ RNIL+ ++ K+SD
Sbjct 713 KNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVN-------SNLVCKVSDF 765
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E I W APE + ++A D W +G + E+ GE
Sbjct 766 GMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER 823
Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + + +RLP P CP L L C E + RP F I+ L +L
Sbjct 824 PYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIR 883
Query 872 HN 873
+
Sbjct 884 NP 885
>sp|P54764|EPHA4_HUMAN Ephrin type-A receptor 4 OS=Homo sapiens
OX=9606 GN=EPHA4 PE=1 SV=1
Length=986
Score = 290 bits (743), Expect = 4e-81, Method: Composition-based stats.
Identities = 86/332 (26%), Positives = 151/332 (45%), Gaps = 21/332 (6%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
+ S+ + + ++ + + +K + +
Sbjct 568 VISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVI 627
Query 904 GEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
G G FG+V G E+ VA+K LKA + R + E I+ H +II
Sbjct 628 GVGEFGEVCSGRLKV--PGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHL 685
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+G K + ++ EY+ GSL +L ++ + QL+ + I GM YL Y+
Sbjct 686 EGVVTKC--KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYV 743
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARN+L++++ + K+ DFG+++ + + E G P+ W APE + KF
Sbjct 744 HRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTS 803
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
ASDVWS+G+ ++E++++ + M+ + + +E G RLP P C
Sbjct 804 ASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVIKAIEEGYRLPPPMDC 849
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P ++ LM +CW+ E S RP F ++ +L +
Sbjct 850 PIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881
Score = 269 bits (687), Expect = 9e-74, Method: Composition-based stats.
Identities = 77/302 (25%), Positives = 124/302 (41%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D I +G G V GRL+V G +E+ V +
Sbjct 614 KEIDASCIKIEKVIGVGEFGEVCSGRLKVPGK---------------------REICVAI 652
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + D F AS+M Q H ++ + GV + +++TEY+E+G LD +LR
Sbjct 653 KTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLR 712
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + + S + YL + + VH ++ RNIL+ ++ K+SD
Sbjct 713 KNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVN-------SNLVCKVSDF 765
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E I W APE + ++A D W +G + E+ GE
Sbjct 766 GMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER 823
Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + + +RLP P CP L L C E + RP F I+ L +L
Sbjct 824 PYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIR 883
Query 872 HN 873
+
Sbjct 884 NP 885
>sp|Q07496|EPHA4_CHICK Ephrin type-A receptor 4 OS=Gallus gallus
OX=9031 GN=EPHA4 PE=1 SV=2
Length=986
Score = 290 bits (743), Expect = 4e-81, Method: Composition-based stats.
Identities = 86/332 (26%), Positives = 151/332 (45%), Gaps = 21/332 (6%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
+ S+ + + ++ + + +K + +
Sbjct 568 VISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVI 627
Query 904 GEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
G G FG+V G E+ VA+K LKA + R + E I+ H +II
Sbjct 628 GVGEFGEVCSGRLKV--PGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHL 685
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+G K + ++ EY+ GSL +L ++ + QL+ + I GM YL Y+
Sbjct 686 EGVVTKC--KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYV 743
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARN+L++++ + K+ DFG+++ + + E G P+ W APE + KF
Sbjct 744 HRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTS 803
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
ASDVWS+G+ ++E++++ + M+ + + +E G RLP P C
Sbjct 804 ASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVIKAIEEGYRLPPPMDC 849
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P ++ LM +CW+ E S RP F ++ +L +
Sbjct 850 PIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881
Score = 269 bits (687), Expect = 9e-74, Method: Composition-based stats.
Identities = 77/302 (25%), Positives = 124/302 (41%), Gaps = 40/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D I +G G V GRL+V G +E+ V +
Sbjct 614 KEIDASCIKIEKVIGVGEFGEVCSGRLKVPGK---------------------REICVAI 652
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + D F AS+M Q H ++ + GV + +++TEY+E+G LD +LR
Sbjct 653 KTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLR 712
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + + S + YL + + VH ++ RNIL+ ++ K+SD
Sbjct 713 KNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVN-------SNLVCKVSDF 765
Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ E I W APE + ++A D W +G + E+ GE
Sbjct 766 GMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER 823
Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + + +RLP P CP L L C E + RP F I+ L +L
Sbjct 824 PYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIR 883
Query 872 HN 873
+
Sbjct 884 NP 885
>sp|P11362|FGFR1_HUMAN Fibroblast growth factor receptor 1 OS=Homo
sapiens OX=9606 GN=FGFR1 PE=1 SV=3
Length=822
Score = 287 bits (734), Expect = 4e-81, Method: Composition-based stats.
Identities = 103/313 (33%), Positives = 153/313 (49%), Gaps = 38/313 (12%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---EMVAVKALKADCG 937
+ P + L + LGEG FG+V L + VAVK LK+D
Sbjct 462 EYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDAT 521
Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990
+ S E+++++ + H++II G C G L +++EY G+LR+YL
Sbjct 522 EKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLQARRPP 579
Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI
Sbjct 580 GLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKI 639
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T
Sbjct 640 ADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--- 695
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L G + V L +LL+ G R+ +P C E+Y +M++CW S R
Sbjct 696 -----------LGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQR 744
Query 1160 PTFENLIPILKTV 1172
PTF+ L+ L +
Sbjct 745 PTFKQLVEDLDRI 757
Score = 236 bits (601), Expect = 2e-63, Method: Composition-based stats.
Identities = 66/348 (19%), Positives = 123/348 (35%), Gaps = 60/348 (17%)
Query 556 GETSNLIIMRGARASPR---------TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606
S ++++R +R S L + + + + LG+G V
Sbjct 436 SMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQV--- 492
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV 665
+ E + + +V +K+L + L +M +
Sbjct 493 --------------VLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMI 538
Query 666 -SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---------------RRERGHVPMA 709
H ++ + G C + ++ EY G L +L +
Sbjct 539 GKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSK 598
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA--- 766
+ A Q+A + YL +K +H ++ RN+L+ + +K++D G+
Sbjct 599 DLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNV-------MKIADFGLARDIHHI 651
Query 767 -LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
++ R+P W+APE L + D W FG L EI G +P E
Sbjct 652 DYYKKTTNGRLPVKWMAPEALFDRI--YTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEEL 709
Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ HR+ P +L + C P+QRP+F+ ++ DL R+
Sbjct 710 FKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 757
>sp|Q04589|FGFR1_RAT Fibroblast growth factor receptor 1 OS=Rattus
norvegicus OX=10116 GN=Fgfr1 PE=1 SV=1
Length=822
Score = 286 bits (733), Expect = 5e-81, Method: Composition-based stats.
Identities = 103/313 (33%), Positives = 153/313 (49%), Gaps = 38/313 (12%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---EMVAVKALKADCG 937
+ P + L + LGEG FG+V L + VAVK LK+D
Sbjct 462 EYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDAT 521
Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990
+ S E+++++ + H++II G C G L +++EY G+LR+YL
Sbjct 522 EKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLQARRPP 579
Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI
Sbjct 580 GLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKI 639
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T
Sbjct 640 ADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--- 695
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L G + V L +LL+ G R+ +P C E+Y +M++CW S R
Sbjct 696 -----------LGGSPNPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWNAVPSQR 744
Query 1160 PTFENLIPILKTV 1172
PTF+ L+ L +
Sbjct 745 PTFKQLVEDLDRI 757
Score = 235 bits (600), Expect = 2e-63, Method: Composition-based stats.
Identities = 66/348 (19%), Positives = 123/348 (35%), Gaps = 60/348 (17%)
Query 556 GETSNLIIMRGARASPR---------TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606
S ++++R +R S L + + + + LG+G V
Sbjct 436 SMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQV--- 492
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV 665
+ E + + +V +K+L + L +M +
Sbjct 493 --------------VLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMI 538
Query 666 -SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---------------RRERGHVPMA 709
H ++ + G C + ++ EY G L +L +
Sbjct 539 GKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSK 598
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA--- 766
+ A Q+A + YL +K +H ++ RN+L+ + +K++D G+
Sbjct 599 DLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNV-------MKIADFGLARDIHHI 651
Query 767 -LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
++ R+P W+APE L + D W FG L EI G +P E
Sbjct 652 DYYKKTTNGRLPVKWMAPEALFDRI--YTHQSDVWSFGVLLWEIFTLGGSPNPGVPVEEL 709
Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ HR+ P +L + C P+QRP+F+ ++ DL R+
Sbjct 710 FKLLKEGHRMDKPSNCTNELYMMMRDCWNAVPSQRPTFKQLVEDLDRI 757
>sp|P21803|FGFR2_MOUSE Fibroblast growth factor receptor 2 OS=Mus
musculus OX=10090 GN=Fgfr2 PE=1 SV=4
Length=821
Score = 286 bits (732), Expect = 6e-81, Method: Composition-based stats.
Identities = 101/313 (32%), Positives = 153/313 (49%), Gaps = 38/313 (12%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCG 937
+ P F + L + LGEG FG+V + + + VAVK LK D
Sbjct 465 EYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDAT 524
Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990
+ S E+++++ + H++II G C G L +++EY G+LR+YL
Sbjct 525 EKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPP 582
Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P + L+ Q+ GM YL +Q IHRDLAARNVL+ + ++KI
Sbjct 583 GMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKI 642
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV ++E+ T
Sbjct 643 ADFGLARDI-NNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT--- 698
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L G + V L +LL+ G R+ +P C E+Y +M++CW S R
Sbjct 699 -----------LGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQR 747
Query 1160 PTFENLIPILKTV 1172
PTF+ L+ L +
Sbjct 748 PTFKQLVEDLDRI 760
Score = 234 bits (597), Expect = 6e-63, Method: Composition-based stats.
Identities = 65/323 (20%), Positives = 117/323 (36%), Gaps = 51/323 (16%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
L + + ++T LG+G V + E +
Sbjct 464 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQV-----------------VMAEAVGIDKD 506
Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689
+ + V +K+L + L +M + H ++ + G C + ++ EY
Sbjct 507 KPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 566
Query 690 VEHGPLDVWLRRER----------GHVPMAW-----KMVVAQQLASALSYLENKNLVHGN 734
G L +LR R VP + QLA + YL ++ +H +
Sbjct 567 ASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD 626
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788
+ RN+L+ + +K++D G+ ++ R+P W+APE L
Sbjct 627 LAARNVLVTENNV-------MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRV 679
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846
+ D W FG + EI G +P E + HR+ P +L +
Sbjct 680 --YTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMR 737
Query 847 QCLTYEPTQRPSFRTILRDLTRL 869
C P+QRP+F+ ++ DL R+
Sbjct 738 DCWHAVPSQRPTFKQLVEDLDRI 760
>sp|P09759|EPHB1_RAT Ephrin type-B receptor 1 OS=Rattus norvegicus
OX=10116 GN=Ephb1 PE=1 SV=2
Length=984
Score = 290 bits (741), Expect = 7e-81, Method: Composition-based stats.
Identities = 79/308 (26%), Positives = 143/308 (46%), Gaps = 21/308 (7%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
++ + ++ ++K +G G FG+V VA
Sbjct 591 MKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKRE-IYVA 649
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LKA + R + E I+ H +II+ +G + + ++ E++ G+L
Sbjct 650 IKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGALDS 707
Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
+L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++
Sbjct 708 FLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 767
Query 1047 AVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
+ + Y G PV W APE + KF ASDVWS+G+ ++E+++ +
Sbjct 768 YLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGER---- 823
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
M+ + +E+ RLP P CP ++ LM +CW+ + + RP F
Sbjct 824 ----------PYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAE 873
Query 1165 LIPILKTV 1172
++ L +
Sbjct 874 IVNTLDKM 881
Score = 278 bits (710), Expect = 7e-77, Method: Composition-based stats.
Identities = 73/304 (24%), Positives = 126/304 (41%), Gaps = 42/304 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G VY+GRL++ G +E+ V +
Sbjct 612 KEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGK---------------------REIYVAI 650
Query 642 KVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L F AS+M Q H ++ + GV + +++TE++E+G LD +LR
Sbjct 651 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 710
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD
Sbjct 711 QNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 763
Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ +IP W APE + ++A D W +G + E+ G
Sbjct 764 GLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSFG 821
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P S + + ++ +RLP P CP L L C + RP F I+ L ++
Sbjct 822 ERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKM 881
Query 870 QPHN 873
+
Sbjct 882 IRNP 885
>sp|Q8CBF3|EPHB1_MOUSE Ephrin type-B receptor 1 OS=Mus musculus
OX=10090 GN=Ephb1 PE=1 SV=1
Length=984
Score = 290 bits (741), Expect = 7e-81, Method: Composition-based stats.
Identities = 79/308 (26%), Positives = 143/308 (46%), Gaps = 21/308 (7%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
++ + ++ ++K +G G FG+V VA
Sbjct 591 MKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKRE-IYVA 649
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LKA + R + E I+ H +II+ +G + + ++ E++ G+L
Sbjct 650 IKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGALDS 707
Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
+L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++
Sbjct 708 FLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 767
Query 1047 AVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
+ + Y G PV W APE + KF ASDVWS+G+ ++E+++ +
Sbjct 768 YLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGER---- 823
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
M+ + +E+ RLP P CP ++ LM +CW+ + + RP F
Sbjct 824 ----------PYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAE 873
Query 1165 LIPILKTV 1172
++ L +
Sbjct 874 IVNTLDKM 881
Score = 278 bits (710), Expect = 7e-77, Method: Composition-based stats.
Identities = 73/304 (24%), Positives = 126/304 (41%), Gaps = 42/304 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G VY+GRL++ G +E+ V +
Sbjct 612 KEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGK---------------------REIYVAI 650
Query 642 KVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L F AS+M Q H ++ + GV + +++TE++E+G LD +LR
Sbjct 651 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 710
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD
Sbjct 711 QNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 763
Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ +IP W APE + ++A D W +G + E+ G
Sbjct 764 GLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSFG 821
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P S + + ++ +RLP P CP L L C + RP F I+ L ++
Sbjct 822 ERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKM 881
Query 870 QPHN 873
+
Sbjct 882 IRNP 885
>sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo sapiens
OX=9606 GN=EPHB1 PE=1 SV=1
Length=984
Score = 289 bits (740), Expect = 9e-81, Method: Composition-based stats.
Identities = 79/308 (26%), Positives = 143/308 (46%), Gaps = 21/308 (7%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
++ + ++ ++K +G G FG+V VA
Sbjct 591 MKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKRE-IYVA 649
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LKA + R + E I+ H +II+ +G + + ++ E++ G+L
Sbjct 650 IKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGALDS 707
Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
+L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++
Sbjct 708 FLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 767
Query 1047 AVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
+ + Y G PV W APE + KF ASDVWS+G+ ++E+++ +
Sbjct 768 YLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGER---- 823
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
M+ + +E+ RLP P CP ++ LM +CW+ + + RP F
Sbjct 824 ----------PYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAE 873
Query 1165 LIPILKTV 1172
++ L +
Sbjct 874 IVNTLDKM 881
Score = 277 bits (709), Expect = 1e-76, Method: Composition-based stats.
Identities = 73/304 (24%), Positives = 126/304 (41%), Gaps = 42/304 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G VY+GRL++ G +E+ V +
Sbjct 612 KEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGK---------------------REIYVAI 650
Query 642 KVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L F AS+M Q H ++ + GV + +++TE++E+G LD +LR
Sbjct 651 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 710
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD
Sbjct 711 QNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVN-------SNLVCKVSDF 763
Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ +IP W APE + ++A D W +G + E+ G
Sbjct 764 GLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSFG 821
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P S + + ++ +RLP P CP L L C + RP F I+ L ++
Sbjct 822 ERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKM 881
Query 870 QPHN 873
+
Sbjct 882 IRNP 885
>sp|Q91287|FGFR3_PLEWA Fibroblast growth factor receptor 3 OS=Pleurodeles
waltl OX=8319 GN=FGFR3 PE=2 SV=1
Length=796
Score = 285 bits (729), Expect = 1e-80, Method: Composition-based stats.
Identities = 104/306 (34%), Positives = 149/306 (49%), Gaps = 38/306 (12%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGW 944
+ L + LGEG FG+V + VAVK LK D + S
Sbjct 448 PKWELSRSRLTLGKPLGEGCFGQVVMADAVGIEKDKPNKATSVAVKMLKDDATDKDLSDL 507
Query 945 KQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------------- 990
E+++++ + H++II G C G L +++EY G+LR+YL
Sbjct 508 VSEMEMMKMIGKHKNIINLLGACTQDG--PLYVLVEYASKGNLREYLRARRPPGMDYSFD 565
Query 991 ----PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
P + L+ A Q+ GM YL +Q IHRDLAARNVL+ +D ++KI DFGLA+
Sbjct 566 TCKLPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLAR 625
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
V +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T
Sbjct 626 DV-HNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFT---------- 674
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L G + V L +LL+ G R+ +P C E+Y +M+ CW S RPTF+ L+
Sbjct 675 ----LGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFKQLV 730
Query 1167 PILKTV 1172
L V
Sbjct 731 EDLDRV 736
Score = 238 bits (607), Expect = 2e-64, Method: Composition-based stats.
Identities = 73/354 (21%), Positives = 128/354 (36%), Gaps = 62/354 (18%)
Query 545 FSLRRC--CLPQPGETSNLIIMRGARAS----PRTLNLSQLSF-----HRVDQKEITQLS 593
F L+R SN ++R R S P N+S+L + + +T
Sbjct 402 FPLKRQVSLESNSSMNSNTPLVRITRLSSSDGPMLANVSELELPADPKWELSRSRLTLGK 461
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LG+G V + + + + V +K+L D L
Sbjct 462 PLGEGCFGQV-----------------VMADAVGIEKDKPNKATSVAVKMLKDDATDKDL 504
Query 654 -AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG------- 704
+M + H ++ + G C + ++ EY G L +LR R
Sbjct 505 SDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSF 564
Query 705 ---HVPMAWK-----MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+P + A Q+A + YL ++ +H ++ RN+L+ + +K
Sbjct 565 DTCKLPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNV-------MK 617
Query 757 LSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
++D G+ ++ R+P W+APE L + D W FG L EI
Sbjct 618 IADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRV--YTHQSDVWSFGVLLWEIFTL 675
Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
G +P E + HR+ P +L + +C P+QRP+F+ +
Sbjct 676 GGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFKQL 729
>sp|P03949|ABL1_CAEEL Tyrosine-protein kinase abl-1 OS=Caenorhabditis
elegans OX=6239 GN=abl-1 PE=1 SV=4
Length=1224
Score = 292 bits (747), Expect = 1e-80, Method: Composition-based stats.
Identities = 95/429 (22%), Positives = 160/429 (37%), Gaps = 66/429 (15%)
Query 450 GIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIE 508
HG + +A L G +L+ S + + ++V R+ + I
Sbjct 194 WYHGKISRSDSEAILGSGITGSFLVRESETSIGQYTISVRHDG---------RVFHYRIN 244
Query 509 QQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGAR 568
+ + F ++ EL + A C L P + +G
Sbjct 245 VDNTEKMFITQEVKFRTLGELVHH---HSVHADGLI-----CLLMYPASKKD----KGRG 292
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
+ N +D+ EI + LG G +VYEG +
Sbjct 293 LFSLSPNAP--DEWELDRSEIIMHNKLGGGQYGDVYEGYWKRHDC--------------- 335
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+ +K L + F A++M + H +L + GVC ++TE
Sbjct 336 ---------TIAVKALKEDAMPLH-EFLAEAAIMKDLHHKNLVRLLGVCTHEAPFYIITE 385
Query 689 YVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
++ +G L +LRR ++ +P + +A Q+AS +SYLE ++ +H ++ RN L++ +
Sbjct 386 FMCNGNLLEYLRRTDKSLLPPIILVQMASQIASGMSYLEARHFIHRDLAARNCLVSEHNI 445
Query 748 AEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGA 802
+K++D G+ I W APE L N+ S+ D W FG
Sbjct 446 -------VKIADFGLARFMKEDTYTAHAGAKFPIKWTAPEGLA--FNTFSSKSDVWAFGV 496
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860
L EI G AP S + R+ P+ P + L QC + P+ RP FR
Sbjct 497 LLWEIATYGMAPYPGVELSNVYGLLENGFRMDGPQGCPPSVYRLMLQCWNWSPSDRPRFR 556
Query 861 TILRDLTRL 869
I +L L
Sbjct 557 DIHFNLENL 565
Score = 271 bits (694), Expect = 9e-74, Method: Composition-based stats.
Identities = 98/292 (34%), Positives = 142/292 (49%), Gaps = 27/292 (9%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
A D + + LG G +G V + +D T +AVKALK D P H
Sbjct 298 PNAPDEWELDRSEIIMHNKLGGGQYGDVYEGYWK-RHDCT---IAVKALKEDAMPLH--E 351
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---L 1000
+ E I++ L+H+++++ G C E ++ E++ G+L +YL R L L
Sbjct 352 FLAEAAIMKDLHHKNLVRLLGVCTH--EAPFYIITEFMCNGNLLEYLRRTDKSLLPPIIL 409
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+ A QI GM+YL A+H+IHRDLAARN L+ +VKI DFGLA+ + E + Y
Sbjct 410 VQMASQIASGMSYLEARHFIHRDLAARNCLVSEHNIVKIADFGLARFMKE--DTYTAHAG 467
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
P+ W APE L F SDVW+FGV L+E+ T+ + +
Sbjct 468 AKFPIKWTAPEGLAFNTFSSKSDVWAFGVLLWEIATYGMA--------------PYPGVE 513
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ + LLE G R+ P CP VY LM CW S RP F ++ L+ +
Sbjct 514 LSNVYGLLENGFRMDGPQGCPPSVYRLMLQCWNWSPSDRPRFRDIHFNLENL 565
>sp|Q91147|FGFR2_NOTVI Fibroblast growth factor receptor 2 OS=Notophthalmus
viridescens OX=8316 GN=FGFR2 PE=2 SV=1
Length=729
Score = 283 bits (724), Expect = 1e-80, Method: Composition-based stats.
Identities = 105/343 (31%), Positives = 157/343 (46%), Gaps = 53/343 (15%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE---MVAVKALKADCG 937
+ P + + L + LGEG FG+V + + + VAVK LK D
Sbjct 373 EYELPEDPKWEYPREKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKDAATVAVKMLKDDAT 432
Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990
+ S E+++++ + H++II G C G L +++EY G+LR+YL
Sbjct 433 EKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRTRRPP 490
Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P + L+ Q+ GM YL +Q IHRDLAARNVL+ ++KI
Sbjct 491 GMEYSFDINRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTETNVMKI 550
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV ++E+ T
Sbjct 551 ADFGLARDI-NNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT--- 606
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L G + V L +LL+ G R+ +P C E+Y +M +CW S R
Sbjct 607 -----------LGGSPYPGIPVEELFKLLKEGHRMDKPGNCTNELYTMMTDCWRAVPSQR 655
Query 1160 PTFENLIPILKTV---------------HEKYQGQAPSVFSVC 1187
PTF+ L+ L + E+Y P S C
Sbjct 656 PTFKQLVEDLDRILTQTTNEEYLDLNNPLEQYSPSYPDTRSSC 698
Score = 231 bits (588), Expect = 2e-62, Method: Composition-based stats.
Identities = 65/332 (20%), Positives = 119/332 (36%), Gaps = 51/332 (15%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
L + ++++T LG+G V + E +
Sbjct 372 SEYELPEDPKWEYPREKLTLGKPLGEGCFGQV-----------------VMAEAVGIDKD 414
Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689
V +K+L + L +M + H ++ + G C + ++ EY
Sbjct 415 RPKDAATVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 474
Query 690 VEHGPLDVWLRRER----------GHVPMAW-----KMVVAQQLASALSYLENKNLVHGN 734
G L +LR R +P + QLA + YL ++ +H +
Sbjct 475 ASKGNLREYLRTRRPPGMEYSFDINRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD 534
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788
+ RN+L+ + +K++D G+ ++ R+P W+APE L
Sbjct 535 LAARNVLVTETNV-------MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRV 587
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846
+ D W FG + EI G +P E + HR+ P +L T+ +
Sbjct 588 --YTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPGNCTNELYTMMT 645
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
C P+QRP+F+ ++ DL R+ +
Sbjct 646 DCWRAVPSQRPTFKQLVEDLDRILTQTTNEEY 677
>sp|Q91285|FGFR1_PLEWA Fibroblast growth factor receptor 1 OS=Pleurodeles
waltl OX=8319 GN=FGFR1 PE=2 SV=1
Length=816
Score = 285 bits (728), Expect = 2e-80, Method: Composition-based stats.
Identities = 102/313 (33%), Positives = 154/313 (49%), Gaps = 38/313 (12%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---EMVAVKALKADCG 937
+ P F + L + LGEG FG+V + + VAVK LK+D
Sbjct 458 EYELPEDPRWEFSRDRLILGKPLGEGCFGQVVMGEAIGLDKEKPNRVTKVAVKMLKSDAT 517
Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----- 991
+ S E+++++ + H++II G C G L +++EY G+LR+YL
Sbjct 518 EKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPP 575
Query 992 ------------RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
+ + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI
Sbjct 576 GMEYCYNPIHVSKDMLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDSVMKI 635
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T
Sbjct 636 ADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--- 691
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L G + V L +LL+ G R+ +P C E+Y +M++CW S R
Sbjct 692 -----------LGGSPYPGVPVEELFKLLKEGHRMDKPGNCTNELYMMMRDCWHAVPSQR 740
Query 1160 PTFENLIPILKTV 1172
PTF+ L+ L +
Sbjct 741 PTFKQLVEDLDRI 753
Score = 235 bits (599), Expect = 3e-63, Method: Composition-based stats.
Identities = 67/343 (20%), Positives = 119/343 (35%), Gaps = 56/343 (16%)
Query 566 GARASPRTLNLSQLSFHRVDQKEIT-----QLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620
+ SP +S+ + E + LG+G V
Sbjct 446 SSSGSPMLTGVSEYELPEDPRWEFSRDRLILGKPLGEGCFGQV----------------- 488
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCV 678
+ E + + +V +K+L + L +M + H ++ + G C
Sbjct 489 VMGEAIGLDKEKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACT 548
Query 679 RGPENIMVTEYVEHGPLDVWLRRERGH---------------VPMAWKMVVAQQLASALS 723
+ ++ EY G L +LR R + + A Q+A +
Sbjct 549 QDGPLYVIVEYASKGNLREYLRARRPPGMEYCYNPIHVSKDMLSFKDLVSCAYQVARGME 608
Query 724 YLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP-- 777
YL +K +H ++ RN+L+ +K++D G+ ++ R+P
Sbjct 609 YLASKKCIHRDLAARNVLVTE-------DSVMKIADFGLARDIHHIDYYKKTTNGRLPVK 661
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PE 835
W+APE L + D W FG L EI G +P E + HR+ P
Sbjct 662 WMAPEALFDRI--YTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPG 719
Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+L + C P+QRP+F+ ++ DL R+
Sbjct 720 NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVAMTSNQEY 762
>sp|P18460|FGFR3_CHICK Fibroblast growth factor receptor 3 OS=Gallus
gallus OX=9031 GN=FGFR3 PE=2 SV=1
Length=806
Score = 285 bits (728), Expect = 2e-80, Method: Composition-based stats.
Identities = 120/415 (29%), Positives = 182/415 (44%), Gaps = 47/415 (11%)
Query 782 ECLPGGANSLSTAMDKWGFG--ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP 839
E L +S S +G L + + + P++K ++ +
Sbjct 354 EELMEMDDSGSVYAGILSYGTGLVLFILVLVIVIICRMKMPNKKAMNTTTVQKVSKFP-- 411
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD-VLTVNPDSPASDPTVFHKRYLK 898
L Q ++ E + T L +TRL + + P + L
Sbjct 412 ----LKRQQVSLESNSSMNSNTPLVRITRLSSSDGPMLANVSELELPPDPKWELARSRLT 467
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGWKQEIDILRTL- 954
+ LGEG FG+V + + VAVK LK D + S E+++++ +
Sbjct 468 LGKPLGEGCFGQVVMAEAIGIDKDKPNKAITVAVKMLKDDATDKDLSDLVSEMEMMKMIG 527
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGL 997
H++II G C G L +++EY G+LR+YL P +
Sbjct 528 KHKNIINLLGACTQDG--PLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKLPEEQLTF 585
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
L+ A Q+ GM YL +Q IHRDLAARNVL+ D ++KI DFGLA+ V +YY+
Sbjct 586 KDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDV-HNIDYYKK 644
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
+G PV W APE L + + + SDVWSFGV L+E+ T L G
Sbjct 645 TTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFT--------------LGGSPYP 690
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ V L +LL+ G R+ +P C ++Y +M+ CW S RPTF+ L+ L V
Sbjct 691 GIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRV 745
Score = 240 bits (612), Expect = 5e-65, Method: Composition-based stats.
Identities = 78/371 (21%), Positives = 136/371 (37%), Gaps = 63/371 (17%)
Query 545 FSLRRCCLPQPGETS---NLIIMRGARAS----PRTLNLSQLSF-----HRVDQKEITQL 592
F L+R + +S N ++R R S P N+S+L + + +T
Sbjct 410 FPLKRQQVSLESNSSMNSNTPLVRITRLSSSDGPMLANVSELELPPDPKWELARSRLTLG 469
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
LG+G V + E + + + V +K+L D
Sbjct 470 KPLGEGCFGQV-----------------VMAEAIGIDKDKPNKAITVAVKMLKDDATDKD 512
Query 653 L-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG------ 704
L +M + H ++ + G C + ++ EY G L +LR R
Sbjct 513 LSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYS 572
Query 705 ----HVPMAWK-----MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+P + A Q+A + YL ++ +H ++ RN+L+ + +
Sbjct 573 FDTCKLPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNV-------M 625
Query 756 KLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
K++D G+ ++ R+P W+APE L + D W FG L EI
Sbjct 626 KIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRV--YTHQSDVWSFGVLLWEIFT 683
Query 810 DGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
G +P E + HR+ P L + +C P+QRP+F+ ++ DL
Sbjct 684 LGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLD 743
Query 868 RLQPHNLADVL 878
R+ D
Sbjct 744 RVLTMTSTDEY 754
>sp|Q64434|PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus musculus
OX=10090 GN=Ptk6 PE=1 SV=1
Length=451
Score = 274 bits (700), Expect = 2e-80, Method: Composition-based stats.
Identities = 99/465 (21%), Positives = 158/465 (34%), Gaps = 83/465 (18%)
Query 418 SLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIH 474
+L +GY +YL A V S G + +L+ ED G +LI
Sbjct 56 ALAEGYV-----PHNYL----AEKETVES-EPWFFGCISRSEAMHRLQAEDNSKGAFLIR 105
Query 475 WSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQ 534
S +L+V +R + I + + + SF ++ EL +
Sbjct 106 VSQKPGADYVLSVRDAQA---------VRHYRIWKNNEGRLHLNEAVSFSNLSELVDYHK 156
Query 535 GCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSH 594
L L C +T L ++E T
Sbjct 157 TQSL---SHGLQLSMPCWKH-----------------KTEPLPHWDDWERPREEFTLCKK 196
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LG G V+E + ++ V +KV+ +
Sbjct 197 LGAGYFGEVFEALWKG-------------------------QVHVAVKVISRDNLLHQHT 231
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMV 713
F M ++ H H+ ++ V G ++TE + G L LR +P+ +
Sbjct 232 FQAEIQAMKKLRHKHILSLYAVATAGDPVYIITELMPKGNLLQLLRDSDEKALPILELVD 291
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSR 769
A Q+A + YLE++N +H ++ RN+L+ L K+ D G+
Sbjct 292 FASQVAEGMCYLESQNYIHRDLAARNVLVTENNL-------CKVGDFGLARLVKEDIYLS 344
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
E W APE L G S D W FG L EI G+ P S E
Sbjct 345 HEHNVPYKWTAPEALSRG--HYSIKSDVWSFGVLLHEIFSRGQMPYPGMSNHETFLRVDA 402
Query 830 QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
+R+P P P + L C + +P QRP F+ + LT + +
Sbjct 403 GYRMPCPLECPPNIHKLMLSCWSRDPKQRPCFKDLCEKLTGITRY 447
Score = 261 bits (667), Expect = 1e-75, Method: Composition-based stats.
Identities = 89/302 (29%), Positives = 140/302 (46%), Gaps = 28/302 (9%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933
+ P D + + LG G+FG+V + VAVK +
Sbjct 168 MPCWKHKTEPLPHWDDWERPREEFTLCKKLGAGYFGEVFEALWKGQ-----VHVAVKVIS 222
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991
D H+ ++ EI ++ L H+HI+ + ++ E +P G+L L
Sbjct 223 RDNLL-HQHTFQAEIQAMKKLRHKHILSLYAVATAGD--PVYIITELMPKGNLLQLLRDS 279
Query 992 -RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
++ + +L+ FA Q+ EGM YL +Q+YIHRDLAARNVL+ + L K+GDFGLA+ V E
Sbjct 280 DEKALPILELVDFASQVAEGMCYLESQNYIHRDLAARNVLVTENNLCKVGDFGLARLVKE 339
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
+ + + P W APE L + SDVWSFGV L+E+ +
Sbjct 340 D---IYLSHEHNVPYKWTAPEALSRGHYSIKSDVWSFGVLLHEIFSRGQ----------- 385
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ M+ ++ G R+P P +CP ++ LM +CW + RP F++L L
Sbjct 386 ---MPYPGMSNHETFLRVDAGYRMPCPLECPPNIHKLMLSCWSRDPKQRPCFKDLCEKLT 442
Query 1171 TV 1172
+
Sbjct 443 GI 444
>sp|Q13882|PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo sapiens
OX=9606 GN=PTK6 PE=1 SV=1
Length=451
Score = 274 bits (700), Expect = 3e-80, Method: Composition-based stats.
Identities = 93/444 (21%), Positives = 151/444 (34%), Gaps = 73/444 (16%)
Query 430 SSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILT 486
+ Y+ H R + G + +L+ E G +LI S +L+
Sbjct 58 AQGYVPHNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLS 117
Query 487 VAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFS 546
V +R + I ++ G + SF S+ EL + L
Sbjct 118 VRDTQA---------VRHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRAQSL---SHGLR 165
Query 547 LRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606
L C E L ++E T LG G V+EG
Sbjct 166 LAAPCRKHEPEP-----------------LPHWDDWERPREEFTLCRKLGSGYFGEVFEG 208
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS 666
+ ++V +KV+ + M ++
Sbjct 209 LWKDR-------------------------VQVAIKVISRDNLLHQQMLQSEIQAMKKLR 243
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYL 725
H H+ ++ V G ++TE + G L LR +P++ + +A Q+A + YL
Sbjct 244 HKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYL 303
Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIPWLAP 781
E++N +H ++ RNIL+ G + K+ D G+ + W AP
Sbjct 304 ESQNYIHRDLAARNILV-------GENTLCKVGDFGLARLIKEDVYLSHDHNIPYKWTAP 356
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCP 839
E L G ST D W FG L E+ G+ P S E +R+P P P
Sbjct 357 EALSRG--HYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPP 414
Query 840 QLATLTSQCLTYEPTQRPSFRTIL 863
+ L C +P QRP F+ +
Sbjct 415 SVHKLMLTCWCRDPEQRPCFKALR 438
Score = 263 bits (671), Expect = 3e-76, Method: Composition-based stats.
Identities = 88/301 (29%), Positives = 135/301 (45%), Gaps = 28/301 (9%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
P D + R LG G+FG+V + VA+K +
Sbjct 169 PCRKHEPEPLPHWDDWERPREEFTLCRKLGSGYFGEVFEGLWKDR-----VQVAIKVISR 223
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--- 991
D H+ + EI ++ L H+HI+ + ++ E + GSL + L
Sbjct 224 DNLL-HQQMLQSEIQAMKKLRHKHILALYAVVSVGD--PVYIITELMAKGSLLELLRDSD 280
Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
+ +++LL A Q+ EGM YL +Q+YIHRDLAARN+L+ + L K+GDFGLA+ + E
Sbjct 281 EKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKED 340
Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111
+ D + P W APE L + SDVWSFG+ L+E+ +
Sbjct 341 ---VYLSHDHNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQ------------ 385
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ M+ ++ G R+P P +CP V+ LM CW + RP F+ L L +
Sbjct 386 --VPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSS 443
Query 1172 V 1172
Sbjct 444 F 444
>sp|Q91735|EPHB3_XENLA Ephrin type-B receptor 3 OS=Xenopus laevis
OX=8355 GN=ephb3 PE=2 SV=1
Length=974
Score = 287 bits (735), Expect = 3e-80, Method: Composition-based stats.
Identities = 79/325 (24%), Positives = 145/325 (45%), Gaps = 21/325 (6%)
Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911
+ + + + ++ + ++ +K +G G FG+V
Sbjct 564 DSESEYTEKLQQYMVPGMKLYIDPFTYEDPNEAVRDFAKEIDISCVKIEEVIGAGEFGEV 623
Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
+ VA+K LKA Q R + E I+ H +II+ +G
Sbjct 624 CRGKLKQAGRRE-QFVAIKTLKAGYTEQQRRDFLGEASIMGQFDHPNIIRLEGVVTRS-- 680
Query 972 KSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029
+ + ++ E++ G+L +L + + QL+ + I GM YL +Y+HRDLAARN+
Sbjct 681 RPVMILTEFMENGALDSFLRMNDGQFTVIQLVGILRGIASGMKYLSEMNYVHRDLAARNI 740
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
L++++ + K+ DFGL++ + Y G P+ W APE + KF ASDVWS+
Sbjct 741 LVNSNLVCKVSDFGLSRFLENSRSDPTYTSALGGKIPIRWTAPEAISYRKFTSASDVWSY 800
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
G+ ++E++++ + M+ + +E+ RLP P CP ++ L
Sbjct 801 GIVMWEVMSYGER--------------PYWDMSNQDVINAIEQDYRLPPPMDCPSALHQL 846
Query 1148 MKNCWETEASFRPTFENLIPILKTV 1172
M +CW + + RP F ++ L +
Sbjct 847 MLDCWLRDRNLRPKFSQIVSSLDKL 871
Score = 265 bits (678), Expect = 1e-72, Method: Composition-based stats.
Identities = 72/293 (25%), Positives = 116/293 (40%), Gaps = 42/293 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G V G+L+ G +E V +
Sbjct 602 KEIDISCVKIEEVIGAGEFGEVCRGKLKQAGR---------------------REQFVAI 640
Query 642 KVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L F AS+M Q H ++ + GV R +++TE++E+G LD +LR
Sbjct 641 KTLKAGYTEQQRRDFLGEASIMGQFDHPNIIRLEGVVTRSRPVMILTEFMENGALDSFLR 700
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G + + + + +AS + YL N VH ++ RNIL+ ++ K+SD
Sbjct 701 MNDGQFTVIQLVGILRGIASGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 753
Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ +IP W APE + ++A D W +G + E+ G
Sbjct 754 GLSRFLENSRSDPTYTSALGGKIPIRWTAPEAIS--YRKFTSASDVWSYGIVMWEVMSYG 811
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTI 862
E P S + + ++ +RLP P CP L L C + RP F I
Sbjct 812 ERPYWDMSNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWLRDRNLRPKFSQI 864
>sp|P22607|FGFR3_HUMAN Fibroblast growth factor receptor 3 OS=Homo
sapiens OX=9606 GN=FGFR3 PE=1 SV=1
Length=806
Score = 284 bits (726), Expect = 3e-80, Method: Composition-based stats.
Identities = 101/291 (35%), Positives = 146/291 (50%), Gaps = 38/291 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGWKQEIDILRTL-YHEH 958
LGEG FG+V + + VAVK LK D + S E+++++ + H++
Sbjct 478 LGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 537
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQLL 1001
II G C G L +++EY G+LR++L P + L+
Sbjct 538 IINLLGACTQGG--PLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLV 595
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
A Q+ GM YL +Q IHRDLAARNVL+ D ++KI DFGLA+ V +YY+ +G
Sbjct 596 SCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDV-HNLDYYKKTTNG 654
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
PV W APE L + + + SDVWSFGV L+E+ T L G + V
Sbjct 655 RLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGIPV 700
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
L +LL+ G R+ +P C ++Y +M+ CW S RPTF+ L+ L V
Sbjct 701 EELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRV 751
Score = 240 bits (612), Expect = 4e-65, Method: Composition-based stats.
Identities = 72/341 (21%), Positives = 126/341 (37%), Gaps = 60/341 (18%)
Query 556 GETSNLIIMRGARAS----PRTLNLSQLSF-----HRVDQKEITQLSHLGQGTRTNVYEG 606
+SN ++R AR S P N+S+L + + +T LG+G V
Sbjct 430 SMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQV--- 486
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV 665
+ E + + + V +K+L D L +M +
Sbjct 487 --------------VMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMI 532
Query 666 -SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG---------------HVPMA 709
H ++ + G C +G ++ EY G L +LR R +
Sbjct 533 GKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFK 592
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA--- 766
+ A Q+A + YL ++ +H ++ RN+L+ + +K++D G+
Sbjct 593 DLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNV-------MKIADFGLARDVHNL 645
Query 767 -LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
++ R+P W+APE L + D W FG L EI G +P E
Sbjct 646 DYYKKTTNGRLPVKWMAPEALFDRV--YTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEEL 703
Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
+ HR+ P L + +C P+QRP+F+ +
Sbjct 704 FKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQL 744
>sp|Q8JH64|BTK_CHICK Tyrosine-protein kinase BTK OS=Gallus gallus
OX=9031 GN=BTK PE=1 SV=1
Length=657
Score = 280 bits (716), Expect = 4e-80, Method: Composition-based stats.
Identities = 86/426 (20%), Positives = 162/426 (38%), Gaps = 63/426 (15%)
Query 446 SIRDGIHGPLLEPFVQAKLRPE--DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLR 503
I + + + L+ E +G +++ STS + ++V +S +R
Sbjct 274 EIYEWYSKNITRSQAEQLLKQEGKEGGFIVRDSTSKTGKYTVSVYAKSAVD---PQGMIR 330
Query 504 KFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLII 563
+ + F ++ EL Q + L+ +
Sbjct 331 HYVVCCTPQNQYYLAEKHLFNTIPELITYHQHN---SAGLISRLKYP------------V 375
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
R +++P T L S+ +D K++T L LG G V G+ R
Sbjct 376 SRHQKSAPSTAGLGYGSW-EIDPKDLTFLKELGTGQFGVVKYGKWRG------------- 421
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
+ V +K++ F + A +M +SH L ++GVC +
Sbjct 422 ------------QYNVAIKMIREGSMS-EDEFIDEAKVMMNLSHEKLVQLYGVCTKQRPI 468
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
++TEY+ +G L +LR + A + + + + A+ YLE+K +H ++ RN L+
Sbjct 469 FIITEYMANGCLLNFLRETQRRFQPAELLEMCKDVCEAMEYLESKQFLHRDLAARNCLVN 528
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKW 798
G+ +K+SD G+ L E + W PE L + S+ D W
Sbjct 529 DQGI-------VKVSDFGLSRYVLDDEYTSSMGSKFPVRWSPPEVLL--YSKFSSKSDVW 579
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
FG + E+ G+ P + + SE + RL P+ + ++ + C + +R
Sbjct 580 SFGVLMWEVYSLGKMPYERFNNSETTEHVIQGLRLYRPQQASERVYAIMYSCWHEKAEER 639
Query 857 PSFRTI 862
P+F +
Sbjct 640 PTFSAL 645
Score = 250 bits (639), Expect = 9e-70, Method: Composition-based stats.
Identities = 84/288 (29%), Positives = 139/288 (48%), Gaps = 27/288 (9%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ L +++LG G FG V + + VA+K ++ G + E
Sbjct 393 WEIDPKDLTFLKELGTGQFGVVKYGKWRGQYN-----VAIKMIRE--GSMSEDEFIDEAK 445
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQI 1007
++ L HE +++ G C Q + + ++ EY+ G L ++L + A+LL + +
Sbjct 446 VMMNLSHEKLVQLYGVCTKQ--RPIFIITEYMANGCLLNFLRETQRRFQPAELLEMCKDV 503
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
CE M YL ++ ++HRDLAARN L+++ +VK+ DFGL++ V + Y PV W
Sbjct 504 CEAMEYLESKQFLHRDLAARNCLVNDQGIVKVSDFGLSRYVLDDE--YTSSMGSKFPVRW 561
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
PE L KF SDVWSFGV ++E+ + L + + TE
Sbjct 562 SPPEVLLYSKFSSKSDVWSFGVLMWEVYS--------------LGKMPYERFNNSETTEH 607
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+ +G RL RP + VY +M +CW +A RPTF L+ + + ++
Sbjct 608 VIQGLRLYRPQQASERVYAIMYSCWHEKAEERPTFSALLGSIVDITDE 655
>sp|Q90344|EPHB2_COTJA Ephrin type-B receptor 2 OS=Coturnix japonica
OX=93934 GN=EPHB2 PE=2 SV=1
Length=987
Score = 287 bits (735), Expect = 4e-80, Method: Composition-based stats.
Identities = 81/325 (25%), Positives = 146/325 (45%), Gaps = 21/325 (6%)
Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911
E T + T ++ + ++ +K + +G G FG+V
Sbjct 577 EYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEV 636
Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
VA+K LK+ + R + E I+ H ++I +G
Sbjct 637 CSGHLKLPGKRE-IFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSS- 694
Query 972 KSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029
+ ++ E++ GSL +L ++ + QL+ + I GM YL +Y+HRDLAARN
Sbjct 695 -PVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNT 753
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
L++++ + K+ DFGL++ + + Y G P+ W APE ++ KF ASDVWS+
Sbjct 754 LVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSY 813
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
G+ ++E++++ + MT + +E+ RLP P CP ++ L
Sbjct 814 GIVMWEVMSYGER--------------PYWDMTNQDVINAIEQDYRLPPPMDCPNALHQL 859
Query 1148 MKNCWETEASFRPTFENLIPILKTV 1172
M +CW+ + + RP F ++ L +
Sbjct 860 MLDCWQKDRNHRPKFGQIVNTLDKM 884
Score = 264 bits (675), Expect = 3e-72, Method: Composition-based stats.
Identities = 69/304 (23%), Positives = 124/304 (41%), Gaps = 42/304 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G V G L++ G +E+ V +
Sbjct 615 KEIDISCVKIEQVIGAGEFGEVCSGHLKLPGK---------------------REIFVAI 653
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + +++TE++E+G LD +LR
Sbjct 654 KTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMIITEFMENGSLDSFLR 713
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL + N VH ++ RN L+ ++ K+SD
Sbjct 714 QNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNTLVN-------SNLVCKVSDF 766
Query 761 GVGL---GALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ S I W APE + ++A D W +G + E+ G
Sbjct 767 GLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYG 824
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P + + + ++ +RLP P CP L L C + RP F I+ L ++
Sbjct 825 ERPYWDMTNQDVINAIEQDYRLPPPMDCPNALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 884
Query 870 QPHN 873
+
Sbjct 885 IRNP 888
>sp|Q8JG38|FGFR2_DANRE Fibroblast growth factor receptor 2 OS=Danio
rerio OX=7955 GN=fgfr2 PE=1 SV=1
Length=817
Score = 284 bits (726), Expect = 4e-80, Method: Composition-based stats.
Identities = 122/433 (28%), Positives = 183/433 (42%), Gaps = 68/433 (16%)
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQC-LTYEPTQ 855
+ G L+ + R+ ++K F + P + LT Q L + T
Sbjct 380 IYCIGVFLIACMVVIVVVCRMRTSAKKPDFSSQ---------PAVHKLTKQIPLRRQVTV 430
Query 856 RPSFRTILRDLTRLQPHNL-----ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910
+ + T L D D P F + L + LGEG FG+
Sbjct 431 SSDSSSSMSSSTPLVRITTRRSSAHDDPIPEYDLPEDPRWEFSRDKLTLGKPLGEGCFGQ 490
Query 911 VSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCC 966
V + + + VAVK LK D + S E+++++ + H++II G C
Sbjct 491 VVMAEALGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGRHKNIINLLGAC 550
Query 967 EDQGEKSLQLVMEYVPLGSLRDYLP-----------------RHSIGLAQLLLFAQQICE 1009
G L +++EY G+LR+YL + L+ Q+
Sbjct 551 TQDG--PLYVIVEYASKGNLREYLRARRPPGMEYSYDIARVSDEPLTFKDLVSCTYQVAR 608
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
GM YL +Q IHRDLAARNVL+ ++KI DFGLA+ V +YY+ +G PV W A
Sbjct 609 GMEYLASQKCIHRDLAARNVLVTESNVMKIADFGLARDV-HNIDYYKKTTNGRLPVKWMA 667
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE L + + + SDVWSFGV ++E+ T L G + V L +LL+
Sbjct 668 PEALFDRVYTHQSDVWSFGVLMWEIFT--------------LGGSPYPGIPVEELFKLLK 713
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH---------------E 1174
G R+ +P C E+Y +MK+CW +S RPTF+ L+ L + E
Sbjct 714 EGHRMDKPANCTNELYMMMKDCWHAISSHRPTFKQLVEDLDRILTLATNEEYLDLCAPVE 773
Query 1175 KYQGQAPSVFSVC 1187
+Y P S C
Sbjct 774 QYSPSFPDTRSSC 786
Score = 229 bits (585), Expect = 2e-61, Method: Composition-based stats.
Identities = 63/322 (20%), Positives = 120/322 (37%), Gaps = 51/322 (16%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
+L + + ++T LG+G V + E +
Sbjct 461 EYDLPEDPRWEFSRDKLTLGKPLGEGCFGQV-----------------VMAEALGIDKDK 503
Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690
+ + V +K+L + L +M + H ++ + G C + ++ EY
Sbjct 504 PKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGRHKNIINLLGACTQDGPLYVIVEYA 563
Query 691 EHGPLDVWLRRERGH-------------VPMAWKMVVA--QQLASALSYLENKNLVHGNV 735
G L +LR R P+ +K +V+ Q+A + YL ++ +H ++
Sbjct 564 SKGNLREYLRARRPPGMEYSYDIARVSDEPLTFKDLVSCTYQVARGMEYLASQKCIHRDL 623
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGAN 789
RN+L+ + +K++D G+ ++ R+P W+APE L
Sbjct 624 AARNVLVTESNV-------MKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRV- 675
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847
+ D W FG + EI G +P E + HR+ P +L +
Sbjct 676 -YTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMKD 734
Query 848 CLTYEPTQRPSFRTILRDLTRL 869
C + RP+F+ ++ DL R+
Sbjct 735 CWHAISSHRPTFKQLVEDLDRI 756
>sp|O13147|EPHB3_DANRE Ephrin type-B receptor 3 (Fragment) OS=Danio
rerio OX=7955 GN=ephb3 PE=2 SV=1
Length=500
Score = 275 bits (703), Expect = 4e-80, Method: Composition-based stats.
Identities = 81/309 (26%), Positives = 135/309 (44%), Gaps = 23/309 (7%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD-PTNDGTGEMV 927
++ + ++ +K +G G FG+V T V
Sbjct 159 VKVYIDPFTYEDPNEAVHEFAREIDISCVKIEEVIGAGEFGEVCRGRLKQAGRKET--TV 216
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LKA R + E I+ H ++I +G + +V E++ G+L
Sbjct 217 AIKTLKAGYTEHQRRDFLSEASIMGQFDHPNVIHLEGVLTRS--CPVLIVTEFMENGALD 274
Query 988 DYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L + QL+ + I GM YL +Y+HRDLAARNVL++++ + K+ DFGL+
Sbjct 275 SFLRLNDGRFTVTQLVGMLRGIAAGMKYLSDMNYVHRDLAARNVLVNSNLVCKVSDFGLS 334
Query 1046 KAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
+ + + Y G P+ W APE + KF ASDVWS+G+ ++E+++ +
Sbjct 335 RFLDDNSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSFGER--- 391
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163
M+ + +E+ RLP P CP ++ LM CW E + RP F
Sbjct 392 -----------PYWDMSNQDVMNAVEQDYRLPPPMDCPAVLHQLMLECWVKERNMRPRFG 440
Query 1164 NLIPILKTV 1172
++ L
Sbjct 441 QIVSTLDKF 449
Score = 260 bits (665), Expect = 7e-75, Method: Composition-based stats.
Identities = 73/292 (25%), Positives = 120/292 (41%), Gaps = 42/292 (14%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
+D + +G G V GRL+ G +E V +K
Sbjct 181 EIDISCVKIEEVIGAGEFGEVCRGRLKQAGR---------------------KETTVAIK 219
Query 643 VLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
L + + F AS+M Q H ++ + GV R ++VTE++E+G LD +LR
Sbjct 220 TLKAGYTEHQRRDFLSEASIMGQFDHPNVIHLEGVLTRSCPVLIVTEFMENGALDSFLRL 279
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
G + + + + +A+ + YL + N VH ++ RN+L+ ++ K+SD G
Sbjct 280 NDGRFTVTQLVGMLRGIAAGMKYLSDMNYVHRDLAARNVLVN-------SNLVCKVSDFG 332
Query 762 VGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
+ +IP W APE + ++A D W +G + E+ GE
Sbjct 333 LSRFLDDNSSDPTYTSSLGGKIPIRWTAPEAIA--FRKFTSASDVWSYGIVMWEVMSFGE 390
Query 813 APLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862
P S + + ++ +RLP P CP L L +C E RP F I
Sbjct 391 RPYWDMSNQDVMNAVEQDYRLPPPMDCPAVLHQLMLECWVKERNMRPRFGQI 442
>sp|Q0VBZ0|CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos taurus
OX=9913 GN=CSK PE=2 SV=1
Length=450
Score = 273 bits (698), Expect = 5e-80, Method: Composition-based stats.
Identities = 102/321 (32%), Positives = 154/321 (48%), Gaps = 33/321 (10%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915
TRL + + D + + LK ++ +G+G FG V L
Sbjct 154 EHYTSDADGLCTRLIKPKVMEGTVAAQDEFFRSGWALNMKDLKLLQTIGKGEFGDVMLGD 213
Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
Y G VAVK +K D Q + E ++ L H ++++ G ++ + L
Sbjct 214 YR------GNKVAVKCIKNDATAQ---AFLAEASVMTQLRHSNLVQLLGVIVEE-KSGLY 263
Query 976 LVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032
+V EY+ GSL DYL R +G LL F+ +CE M YL +++HRDLAARNVL+
Sbjct 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
D + K+ DFGL K E ++ G PV W APE L+E KF SDVWSFG+ L+
Sbjct 324 EDNVAKVSDFGLTK------EASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLW 377
Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152
E+ + + ++ + + +E+G ++ PD CP VY +MKNCW
Sbjct 378 EIYSFGR--------------VPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCW 423
Query 1153 ETEASFRPTFENLIPILKTVH 1173
+A+ RP+F L L+ +
Sbjct 424 HLDAATRPSFLQLREQLERIK 444
Score = 259 bits (663), Expect = 4e-75, Method: Composition-based stats.
Identities = 98/436 (22%), Positives = 166/436 (38%), Gaps = 70/436 (16%)
Query 446 SIRDGIHGPLLEPFVQAKL-RPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
S+ HG + + L PE GL+L+ ST++P L V + DG +
Sbjct 78 SLMPWFHGKITREQAERLLCPPETGLFLVRESTNYPGDYTLCV-----SCDGK----VEH 128
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ I ++ F ++ +L A C L + + + +
Sbjct 129 YRIMYHASKLSID-EEVYFENLMQLVEHYTSD---ADGLCTRLIKPKVMEGTVAAQDEFF 184
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
R ++ K++ L +G+G +V G R
Sbjct 185 RSG--------------WALNMKDLKLLQTIGKGEFGDVMLGDYRGN------------- 217
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE-N 683
+V +K + A AF AS+M+Q+ H++L + GV V
Sbjct 218 -------------KVAVKCIKNDAT--AQAFLAEASVMTQLRHSNLVQLLGVIVEEKSGL 262
Query 684 IMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+VTEY+ G L +LR R R + + + + A+ YLE N VH ++ RN+L+
Sbjct 263 YIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLV 322
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFG 801
+ +A K+SD G+ A S ++ + + W APE L ST D W FG
Sbjct 323 SEDNVA-------KVSDFGLTKEASSTQDTGKLPVKWTAPEALRE--KKFSTKSDVWSFG 373
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859
L EI G P + ++ +++ P+ P + + C + RPSF
Sbjct 374 ILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPSF 433
Query 860 RTILRDLTRLQPHNLA 875
+ L R++ H L
Sbjct 434 LQLREQLERIKTHELH 449
>sp|P41240|CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo sapiens
OX=9606 GN=CSK PE=1 SV=1
Length=450
Score = 273 bits (697), Expect = 6e-80, Method: Composition-based stats.
Identities = 102/321 (32%), Positives = 154/321 (48%), Gaps = 33/321 (10%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915
TRL + + D + + LK ++ +G+G FG V L
Sbjct 154 EHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGD 213
Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
Y G VAVK +K D Q + E ++ L H ++++ G ++ + L
Sbjct 214 YR------GNKVAVKCIKNDATAQ---AFLAEASVMTQLRHSNLVQLLGVIVEE-KGGLY 263
Query 976 LVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032
+V EY+ GSL DYL R +G LL F+ +CE M YL +++HRDLAARNVL+
Sbjct 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
D + K+ DFGL K E ++ G PV W APE L+E KF SDVWSFG+ L+
Sbjct 324 EDNVAKVSDFGLTK------EASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLW 377
Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152
E+ + + ++ + + +E+G ++ PD CP VY +MKNCW
Sbjct 378 EIYSFGR--------------VPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCW 423
Query 1153 ETEASFRPTFENLIPILKTVH 1173
+A+ RP+F L L+ +
Sbjct 424 HLDAAMRPSFLQLREQLEHIK 444
Score = 261 bits (666), Expect = 1e-75, Method: Composition-based stats.
Identities = 100/436 (23%), Positives = 166/436 (38%), Gaps = 70/436 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRP-EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
S+ HG + + L P E GL+L+ ST++P L V + DG +
Sbjct 78 SLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCV-----SCDGK----VEH 128
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ I ++ F ++ +L A C L + +M
Sbjct 129 YRIMYHASKLSID-EEVYFENLMQLVEHYTSD---ADGLCTRLIKP-----------KVM 173
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
G A+ S ++ KE+ L +G+G +V G R
Sbjct 174 EGTVAAQDEF---YRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGN------------- 217
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV-CVRGPEN 683
+V +K + A AF AS+M+Q+ H++L + GV
Sbjct 218 -------------KVAVKCIKNDAT--AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGL 262
Query 684 IMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+VTEY+ G L +LR R R + + + + A+ YLE N VH ++ RN+L+
Sbjct 263 YIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLV 322
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFG 801
+ +A K+SD G+ A S ++ + + W APE L ST D W FG
Sbjct 323 SEDNVA-------KVSDFGLTKEASSTQDTGKLPVKWTAPEALRE--KKFSTKSDVWSFG 373
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859
L EI G P + ++ +++ P+ P + + C + RPSF
Sbjct 374 ILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSF 433
Query 860 RTILRDLTRLQPHNLA 875
+ L ++ H L
Sbjct 434 LQLREQLEHIKTHELH 449
>sp|P22182|FGFR1_XENLA Fibroblast growth factor receptor 1 OS=Xenopus
laevis OX=8355 GN=fgfr1 PE=1 SV=1
Length=812
Score = 283 bits (724), Expect = 7e-80, Method: Composition-based stats.
Identities = 105/335 (31%), Positives = 157/335 (47%), Gaps = 45/335 (13%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---EMVAVKALKADCG 937
+ P + L + LGEG FG+V + + VAVK LK+D
Sbjct 456 EYELPEDPRWEVARDRLILGKPLGEGCFGQVVMAEAIGLDKEKPNKVTKVAVKMLKSDAS 515
Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-- 994
+ S E+++++ + H++II G C G L +++EY G+LR+YL
Sbjct 516 EKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYTSKGNLREYLRARRPP 573
Query 995 ---------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
+ L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI
Sbjct 574 AMEYCYNPTCVPDQLLSFKDLVSCAYQVARGMDYLASKKCIHRDLAARNVLVTEDNIMKI 633
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T
Sbjct 634 ADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--- 689
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L G + + L +LL+ G R+ +P C E+Y +MK+CW S R
Sbjct 690 -----------LGGSPYPGVPMEELFKLLKEGHRMDKPTNCTNELYMMMKDCWHAMPSQR 738
Query 1160 PTFENLIPILKTV------HEKYQGQAP-SVFSVC 1187
PTF L+ L + E P + +S C
Sbjct 739 PTFNQLVEDLDRILALSSNQEYLDLSMPVNQYSPC 773
Score = 235 bits (600), Expect = 2e-63, Method: Composition-based stats.
Identities = 67/362 (19%), Positives = 119/362 (33%), Gaps = 51/362 (14%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
L + V + + LG+G V + E +
Sbjct 455 SEYELPEDPRWEVARDRLILGKPLGEGCFGQV-----------------VMAEAIGLDKE 497
Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689
+ +V +K+L + L +M + H ++ + G C + ++ EY
Sbjct 498 KPNKVTKVAVKMLKSDASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 557
Query 690 VEHGPLDVWLRRERGH---------------VPMAWKMVVAQQLASALSYLENKNLVHGN 734
G L +LR R + + A Q+A + YL +K +H +
Sbjct 558 TSKGNLREYLRARRPPAMEYCYNPTCVPDQLLSFKDLVSCAYQVARGMDYLASKKCIHRD 617
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788
+ RN+L+ + +K++D G+ ++ R+P W+APE L
Sbjct 618 LAARNVLVTEDNI-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRI 670
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846
+ D W FG L EI G +P E + HR+ P +L +
Sbjct 671 --YTHQSDVWSFGVLLWEIFTLGGSPYPGVPMEELFKLLKEGHRMDKPTNCTNELYMMMK 728
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906
C P+QRP+F ++ DL R+ + F +
Sbjct 729 DCWHAMPSQRPTFNQLVEDLDRILALSSNQEYLDLSMPVNQYSPCFPDTRSSTCSSGEDS 788
Query 907 HF 908
F
Sbjct 789 MF 790
>sp|P32577|CSK_RAT Tyrosine-protein kinase CSK OS=Rattus norvegicus
OX=10116 GN=Csk PE=1 SV=1
Length=450
Score = 273 bits (697), Expect = 7e-80, Method: Composition-based stats.
Identities = 103/321 (32%), Positives = 154/321 (48%), Gaps = 33/321 (10%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915
TRL + + D + + LK ++ +G+G FG V L
Sbjct 154 EHYTTDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGD 213
Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
Y G VAVK +K D Q + E ++ L H ++++ G ++ + L
Sbjct 214 YR------GNKVAVKCIKNDATAQ---AFLAEASVMTQLRHSNLVQLLGVIVEE-KGGLY 263
Query 976 LVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032
+V EY+ GSL DYL R +G LL F+ +CE M YL +++HRDLAARNVL+
Sbjct 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
D + K+ DFGL K E ++ G PV W APE L+E KF SDVWSFG+ L+
Sbjct 324 EDNVAKVSDFGLTK------EASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLW 377
Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152
E+ + + ++ + + +E+G ++ PD CP VY +MKNCW
Sbjct 378 EIYSFGR--------------VPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYDVMKNCW 423
Query 1153 ETEASFRPTFENLIPILKTVH 1173
+A+ RPTF L L+ +
Sbjct 424 HLDAATRPTFLQLREQLEHIR 444
Score = 262 bits (669), Expect = 4e-76, Method: Composition-based stats.
Identities = 98/436 (22%), Positives = 165/436 (38%), Gaps = 70/436 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRP-EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
S+ HG + + L P E GL+L+ ST++P L V+ + K
Sbjct 78 SLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASK 137
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
I+++ F ++ +L A C L + +M
Sbjct 138 LSIDEE----------VYFENLMQLVEHYTTD---ADGLCTRLIKP-----------KVM 173
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
G A+ S ++ KE+ L +G+G +V G R
Sbjct 174 EGTVAAQDEF---YRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGN------------- 217
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV-CVRGPEN 683
+V +K + A AF AS+M+Q+ H++L + GV
Sbjct 218 -------------KVAVKCIKNDAT--AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGL 262
Query 684 IMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+VTEY+ G L +LR R R + + + + A+ YLE N VH ++ RN+L+
Sbjct 263 YIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLV 322
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFG 801
+ +A K+SD G+ A S ++ + + W APE L ST D W FG
Sbjct 323 SEDNVA-------KVSDFGLTKEASSTQDTGKLPVKWTAPEALRE--KKFSTKSDVWSFG 373
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859
L EI G P + ++ +++ P+ P + + C + RP+F
Sbjct 374 ILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYDVMKNCWHLDAATRPTF 433
Query 860 RTILRDLTRLQPHNLA 875
+ L ++ H L
Sbjct 434 LQLREQLEHIRTHELH 449
>sp|P41241|CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus musculus
OX=10090 GN=Csk PE=1 SV=2
Length=450
Score = 272 bits (696), Expect = 1e-79, Method: Composition-based stats.
Identities = 103/321 (32%), Positives = 154/321 (48%), Gaps = 33/321 (10%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915
TRL + + D + + LK ++ +G+G FG V L
Sbjct 154 EHYTTDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGD 213
Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
Y G VAVK +K D Q + E ++ L H ++++ G ++ + L
Sbjct 214 YR------GNKVAVKCIKNDATAQ---AFLAEASVMTQLRHSNLVQLLGVIVEE-KGGLY 263
Query 976 LVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032
+V EY+ GSL DYL R +G LL F+ +CE M YL +++HRDLAARNVL+
Sbjct 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
D + K+ DFGL K E ++ G PV W APE L+E KF SDVWSFG+ L+
Sbjct 324 EDNVAKVSDFGLTK------EASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLW 377
Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152
E+ + + ++ + + +E+G ++ PD CP VY +MKNCW
Sbjct 378 EIYSFGR--------------VPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCW 423
Query 1153 ETEASFRPTFENLIPILKTVH 1173
+A+ RPTF L L+ +
Sbjct 424 HLDAATRPTFLQLREQLEHIK 444
Score = 262 bits (669), Expect = 5e-76, Method: Composition-based stats.
Identities = 98/436 (22%), Positives = 165/436 (38%), Gaps = 70/436 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRP-EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
S+ HG + + L P E GL+L+ ST++P L V+ + K
Sbjct 78 SLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASK 137
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
I+++ F ++ +L A C L + +M
Sbjct 138 LSIDEE----------VYFENLMQLVEHYTTD---ADGLCTRLIKP-----------KVM 173
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
G A+ S ++ KE+ L +G+G +V G R
Sbjct 174 EGTVAAQDEF---YRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGN------------- 217
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV-CVRGPEN 683
+V +K + A AF AS+M+Q+ H++L + GV
Sbjct 218 -------------KVAVKCIKNDAT--AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGL 262
Query 684 IMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+VTEY+ G L +LR R R + + + + A+ YLE N VH ++ RN+L+
Sbjct 263 YIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLV 322
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFG 801
+ +A K+SD G+ A S ++ + + W APE L ST D W FG
Sbjct 323 SEDNVA-------KVSDFGLTKEASSTQDTGKLPVKWTAPEALRE--KKFSTKSDVWSFG 373
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859
L EI G P + ++ +++ P+ P + + C + RP+F
Sbjct 374 ILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPTF 433
Query 860 RTILRDLTRLQPHNLA 875
+ L ++ H L
Sbjct 434 LQLREQLEHIKTHELH 449
>sp|Q498D6|FGFR4_RAT Fibroblast growth factor receptor 4 OS=Rattus
norvegicus OX=10116 GN=Fgfr4 PE=1 SV=1
Length=800
Score = 282 bits (721), Expect = 1e-79, Method: Composition-based stats.
Identities = 102/304 (34%), Positives = 149/304 (49%), Gaps = 38/304 (13%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE---MVAVKALKADCGPQHRSGWKQ 946
F + L + LGEG FG+V + + VAVK LK + + +
Sbjct 458 WEFPRDRLVLGKPLGEGCFGQVVRAEALGMDSSRPDQTSTVAVKMLKDNASDKDLADLIS 517
Query 947 EIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-------------- 991
E+++++ + H++II G C +G L +++EY G+LR++L
Sbjct 518 EMEMMKLIGRHKNIINLLGVCTQEG--PLYVIVEYAAKGNLREFLRARRPPGPDLSPDGP 575
Query 992 ---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ V
Sbjct 576 RSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDDVMKIADFGLARGV 635
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
+YY+ +G PV W APE L + + + SDVWSFG+ L+E+ T
Sbjct 636 HH-IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFT------------ 682
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
L G + V L LL G R+ RP CP E+Y LM+ CW S RPTF+ L+
Sbjct 683 --LGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRECWHAAPSQRPTFKQLVEA 740
Query 1169 LKTV 1172
L V
Sbjct 741 LDKV 744
Score = 238 bits (606), Expect = 2e-64, Method: Composition-based stats.
Identities = 66/315 (21%), Positives = 114/315 (36%), Gaps = 51/315 (16%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
+L+L + + LG+G V + E +
Sbjct 449 SLDLPLDPLWEFPRDRLVLGKPLGEGCFGQV-----------------VRAEALGMDSSR 491
Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690
Q V +K+L + D L +M + H ++ + GVC + ++ EY
Sbjct 492 PDQTSTVAVKMLKDNASDKDLADLISEMEMMKLIGRHKNIINLLGVCTQEGPLYVIVEYA 551
Query 691 EHGPLDVWLRRER---------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNV 735
G L +LR R G + + A Q+A + YLE++ +H ++
Sbjct 552 AKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDL 611
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGAN 789
RN+L+ +K++D G+ G + + + W+APE L
Sbjct 612 AARNVLVTE-------DDVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRV- 663
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847
+ D W FG L EI G +P E + HR+ P +L L +
Sbjct 664 -YTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRE 722
Query 848 CLTYEPTQRPSFRTI 862
C P+QRP+F+ +
Sbjct 723 CWHAAPSQRPTFKQL 737
>sp|P42680|TEC_HUMAN Tyrosine-protein kinase Tec OS=Homo sapiens
OX=9606 GN=TEC PE=1 SV=2
Length=631
Score = 278 bits (710), Expect = 1e-79, Method: Composition-based stats.
Identities = 87/428 (20%), Positives = 162/428 (38%), Gaps = 66/428 (15%)
Query 460 VQAKLRPE--DGLYLIHWSTSHPYRLILTVAQR--SQAPDGMQSLRLRKFPIEQQDGAFV 515
+ LR E +G +++ S S P +++ + + G + +++ +
Sbjct 257 AEQLLRSEDKEGGFMVRDS-SQPGLYTVSLYTKFGGEGSSGFRHYHIKE--TTTSPKKYY 313
Query 516 LEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLN 575
L +F S+ E+ + A LR + + +P T
Sbjct 314 L-AEKHAFGSIPEIIEYHKHN---AAGLVTRLRYP------------VSVKGKNAPTTAG 357
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
S ++ E+T + LG G V G+ R
Sbjct 358 FSY-EKWEINPSELTFMRELGSGLFGVVRLGKWRA------------------------- 391
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+ +V +K + F E A +M +++H L ++GVC + +VTE++E G L
Sbjct 392 QYKVAIKAIREGAM-CEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCL 450
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+LR+ +GH + + Q + + YLE + +H ++ RN L++ G+ +
Sbjct 451 LNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGV-------V 503
Query 756 KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K+SD G+ L + + W PE + S+ D W FG + E+ +
Sbjct 504 KVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVF--NYSRFSSKSDVWSFGVLMWEVFTE 561
Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
G P + + E R HRL P+ + + + +C +P RPSF +LR +
Sbjct 562 GRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDE 621
Query 869 LQPHNLAD 876
L
Sbjct 622 LVECEETF 629
Score = 254 bits (650), Expect = 2e-71, Method: Composition-based stats.
Identities = 86/292 (29%), Positives = 136/292 (47%), Gaps = 27/292 (9%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
+ + + L +R+LG G FG V L + VA+KA++ G +
Sbjct 358 FSYEKWEINPSELTFMRELGSGLFGVVRLGKWRAQYK-----VAIKAIRE--GAMCEEDF 410
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLL 1002
+E ++ L H +++ G C Q K + +V E++ G L ++L + LL
Sbjct 411 IEEAKVMMKLTHPKLVQLYGVCTQQ--KPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLS 468
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
Q +CEGM YL +IHRDLAARN L+ +VK+ DFG+A+ V + + Y
Sbjct 469 MCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLD--DQYTSSSGAK 526
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
PV W PE +F SDVWSFGV ++E+ T + + T
Sbjct 527 FPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGR--------------MPFEKYTNY 572
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ ++ RG RL +P VY +M CW+ + RP+FE+L+ + + E
Sbjct 573 EVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDELVE 624
>sp|Q91288|FGFR4_PLEWA Fibroblast growth factor receptor 4 OS=Pleurodeles
waltl OX=8319 GN=FGFR4 PE=2 SV=1
Length=822
Score = 282 bits (722), Expect = 2e-79, Method: Composition-based stats.
Identities = 105/350 (30%), Positives = 159/350 (45%), Gaps = 38/350 (11%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
L Q + S +++R + D P F + L + L
Sbjct 433 LMRQFSLESSSSGKSSTSLVRVTRLSSSCTPMLPGVLEFDLPLDSKWEFPRERLVLGKPL 492
Query 904 GEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGWKQEIDILRTL-YHEHI 959
GEG FG+V N + VA+K +K + S E+++++ + H++I
Sbjct 493 GEGCFGQVVRAEAYGINKDQPDKAITVAIKIVKDKGTDKELSDLISEMELMKLMGKHKNI 552
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQLLL 1002
I G C G L +++EY G+LR++L P + L+
Sbjct 553 INLLGVCTQDG--PLYMIVEYASKGNLREFLRARRPPSPDYTFDMTKVPEEQLSFQDLVS 610
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
+ Q+ GMAYL ++ IHRDLAARNVL+ + ++KI DFGLA+ V +YY+ +G
Sbjct 611 CSYQVARGMAYLESKRCIHRDLAARNVLVTGENVMKIADFGLARGV-HDIDYYKKTSNGR 669
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
PV W APE L + + + SDVWSFGV +E+ T L G + V
Sbjct 670 LPVKWMAPEALFDRVYTHQSDVWSFGVLTWEIFT--------------LGGSPYPGIPVE 715
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
L +LL G R+ +P C E+Y LM+ CW S RPTF+ L+ L +
Sbjct 716 ELFKLLREGHRMDKPSNCTHELYMLMRECWHAAPSQRPTFKQLVETLDRI 765
Score = 233 bits (594), Expect = 1e-62, Method: Composition-based stats.
Identities = 70/355 (20%), Positives = 124/355 (35%), Gaps = 51/355 (14%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
+L S ++ + LG+G V + E +
Sbjct 470 EFDLPLDSKWEFPRERLVLGKPLGEGCFGQV-----------------VRAEAYGINKDQ 512
Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690
+ + V +K++ D L LM + H ++ + GVC + M+ EY
Sbjct 513 PDKAITVAIKIVKDKGTDKELSDLISEMELMKLMGKHKNIINLLGVCTQDGPLYMIVEYA 572
Query 691 EHGPLDVWLRRERGHVP---------------MAWKMVVAQQLASALSYLENKNLVHGNV 735
G L +LR R P + + Q+A ++YLE+K +H ++
Sbjct 573 SKGNLREFLRARRPPSPDYTFDMTKVPEEQLSFQDLVSCSYQVARGMAYLESKRCIHRDL 632
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGAN 789
RN+L+ + +K++D G+ G + + + W+APE L
Sbjct 633 AARNVLVTGENV-------MKIADFGLARGVHDIDYYKKTSNGRLPVKWMAPEALFDRV- 684
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847
+ D W FG EI G +P E + HR+ P +L L +
Sbjct 685 -YTHQSDVWSFGVLTWEIFTLGGSPYPGIPVEELFKLLREGHRMDKPSNCTHELYMLMRE 743
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902
C P+QRP+F+ ++ L R+ + L ++ P D
Sbjct 744 CWHAAPSQRPTFKQLVETLDRILATVAEEYLDLSMPFEQYSPACEDTTSTCSSDD 798
>sp|Q61851|FGFR3_MOUSE Fibroblast growth factor receptor 3 OS=Mus
musculus OX=10090 GN=Fgfr3 PE=1 SV=1
Length=801
Score = 282 bits (721), Expect = 2e-79, Method: Composition-based stats.
Identities = 100/306 (33%), Positives = 148/306 (48%), Gaps = 37/306 (12%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGW 944
+ L + LGEG FG+V + + VAVK LK D + S
Sbjct 457 PKWELSRTRLTLGKPLGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDL 516
Query 945 KQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------------- 990
E+++++ + H++II G C G L +++EY G+LR++L
Sbjct 517 VSEMEMMKMIGKHKNIINLLGACTQGG--PLYVLVEYAAKGNLREFLRARRPPGMDYSFD 574
Query 991 ----PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
P + L+ A Q+ GM YL +Q IHRDLAARNVL+ D ++KI DFGLA+
Sbjct 575 ACRLPEEQLTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLAR 634
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
V +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T S
Sbjct 635 DV-HNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTPGGPS----- 688
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ V L +LL+ G R+ +P C ++Y +M+ CW S RPTF+ L+
Sbjct 689 --------PYPGIPVEELFKLLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTFKQLV 740
Query 1167 PILKTV 1172
L +
Sbjct 741 EDLDRI 746
Score = 237 bits (605), Expect = 4e-64, Method: Composition-based stats.
Identities = 79/362 (22%), Positives = 135/362 (37%), Gaps = 63/362 (17%)
Query 545 FSLRRC--CLPQPGETSNLIIMRGARAS----PRTLNLSQLSF-----HRVDQKEITQLS 593
F L+R SN ++R AR S P N+S+L + + +T
Sbjct 411 FPLKRQVSLESNSSMNSNTPLVRIARLSSGEGPVLANVSELELPADPKWELSRTRLTLGK 470
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LG+G V + E + + + V +K+L D L
Sbjct 471 PLGEGCFGQV-----------------VMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDL 513
Query 654 -AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG------- 704
+M + H ++ + G C +G ++ EY G L +LR R
Sbjct 514 SDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGMDYSF 573
Query 705 ---HVPMAWK-----MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+P + A Q+A + YL ++ +H ++ RN+L+ + +K
Sbjct 574 DACRLPEEQLTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNV-------MK 626
Query 757 LSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICF- 809
++D G+ ++ R+P W+APE L + D W FG L EI
Sbjct 627 IADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRV--YTHQSDVWSFGVLLWEIFTP 684
Query 810 DGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
G +P E + HR+ P L + +C P+QRP+F+ ++ DL
Sbjct 685 GGPSPYPGIPVEELFKLLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTFKQLVEDLD 744
Query 868 RL 869
R+
Sbjct 745 RI 746
>sp|Q03364|FGFR2_XENLA Fibroblast growth factor receptor 2 OS=Xenopus
laevis OX=8355 GN=fgfr2 PE=2 SV=1
Length=813
Score = 282 bits (721), Expect = 2e-79, Method: Composition-based stats.
Identities = 101/320 (32%), Positives = 154/320 (48%), Gaps = 38/320 (12%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVK 930
+ + P F + L + LGEG FG+V + + + VAVK
Sbjct 448 MPLANVSEYELPHDPMWEFSRDKLTLGKPLGEGCFGQVVMAEALGIDKERPKESVTVAVK 507
Query 931 ALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
LK + + + E+++++ + H++II G C G +L +++EY G+LR Y
Sbjct 508 MLKDNATEKDLADLVSEMEMMKMIGKHKNIINLLGACTQGG--TLYVIVEYAAKGNLRQY 565
Query 990 L-----------------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032
L P + L+ QI GM YL +Q IHRDLAARNVL+
Sbjct 566 LRARRPLEMEYSFDVTRVPDEQMTFKDLVSCTYQIARGMEYLASQKCIHRDLAARNVLVT 625
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
+ ++KI DFGLA+ V +YY+ +G PV W APE L + + + SDVWSFGV ++
Sbjct 626 ENNVMKIADFGLARDV-NNIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMW 684
Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152
E+ T L G + V L +LL+ G R+ +P C E+Y +M++CW
Sbjct 685 EIFT--------------LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCW 730
Query 1153 ETEASFRPTFENLIPILKTV 1172
S RPTF+ L+ L +
Sbjct 731 HAIPSHRPTFKQLVEDLDRI 750
Score = 231 bits (589), Expect = 6e-62, Method: Composition-based stats.
Identities = 63/326 (19%), Positives = 118/326 (36%), Gaps = 51/326 (16%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
A+ L + ++T LG+G V + E +
Sbjct 451 ANVSEYELPHDPMWEFSRDKLTLGKPLGEGCFGQV-----------------VMAEALGI 493
Query 629 PGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMV 686
+ + V +K+L + + L +M + H ++ + G C +G ++
Sbjct 494 DKERPKESVTVAVKMLKDNATEKDLADLVSEMEMMKMIGKHKNIINLLGACTQGGTLYVI 553
Query 687 TEYVEHGPLDVWLRRERG---------------HVPMAWKMVVAQQLASALSYLENKNLV 731
EY G L +LR R + + Q+A + YL ++ +
Sbjct 554 VEYAAKGNLRQYLRARRPLEMEYSFDVTRVPDEQMTFKDLVSCTYQIARGMEYLASQKCI 613
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLP 785
H ++ RN+L+ + +K++D G+ ++ R+P W+APE L
Sbjct 614 HRDLAARNVLVTENNV-------MKIADFGLARDVNNIDYYKKTSNGRLPVKWMAPEALF 666
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLAT 843
+ D W FG + EI G +P E + HR+ P +L
Sbjct 667 DRV--YTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYM 724
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869
+ C P+ RP+F+ ++ DL R+
Sbjct 725 MMRDCWHAIPSHRPTFKQLVEDLDRI 750
>sp|Q91286|FGFR2_PLEWA Fibroblast growth factor receptor 2 OS=Pleurodeles
waltl OX=8319 GN=FGFR2 PE=2 SV=1
Length=824
Score = 281 bits (720), Expect = 3e-79, Method: Composition-based stats.
Identities = 100/313 (32%), Positives = 150/313 (48%), Gaps = 38/313 (12%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE---MVAVKALKADCG 937
+ P + + L + LGEG FG+V + + + VAVK LK D
Sbjct 462 EYELPEDPKWEYPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKDAVTVAVKMLKDDAT 521
Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990
+ S E+++++ + H++II G C G L +++EY G+LR+YL
Sbjct 522 EKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRTRRPP 579
Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P + L+ Q+ GM YL +Q IHRDLAARNVL+ ++KI
Sbjct 580 GMEYSFDIFRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTETNVIKI 639
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLA+ + +YY+ +G PV W APE L + + SDVWSFGV ++E+ T
Sbjct 640 ADFGLARDI-NNIDYYKKTTNGRLPVKWMAPEALFDRVYTLQSDVWSFGVLMWEIFT--- 695
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L G + V L +LL+ G R+ +P C E+Y +M +CW S R
Sbjct 696 -----------LGGSPYPGIPVEELFKLLKEGHRMVKPGNCTNELYTMMTDCWRAVPSQR 744
Query 1160 PTFENLIPILKTV 1172
PTF+ L+ L +
Sbjct 745 PTFKQLVEDLDRI 757
Score = 232 bits (592), Expect = 2e-62, Method: Composition-based stats.
Identities = 66/356 (19%), Positives = 121/356 (34%), Gaps = 51/356 (14%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
L + + ++T LG+G V + E +
Sbjct 461 SEYELPEDPKWEYPRDKLTLGKPLGEGCFGQV-----------------VMAEAVGIDKD 503
Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689
+ V +K+L + L +M + H ++ + G C + ++ EY
Sbjct 504 RPKDAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 563
Query 690 VEHGPLDVWLRRERG----------HVPMAW-----KMVVAQQLASALSYLENKNLVHGN 734
G L +LR R +P + QLA + YL ++ +H +
Sbjct 564 ASKGNLREYLRTRRPPGMEYSFDIFRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD 623
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788
+ RN+L+ + IK++D G+ ++ R+P W+APE L
Sbjct 624 LAARNVLVTETNV-------IKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRV 676
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846
+ D W FG + EI G +P E + HR+ P +L T+ +
Sbjct 677 --YTLQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMVKPGNCTNELYTMMT 734
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902
C P+QRP+F+ ++ DL R+ + + +
Sbjct 735 DCWRAVPSQRPTFKQLVEDLDRILTQTTNEEYLDLNNPLEPYSPSYPDTRSSCSFG 790
>sp|Q07494|EPHB1_CHICK Ephrin type-B receptor 1 (Fragment) OS=Gallus
gallus OX=9031 GN=EPHB1 PE=2 SV=2
Length=984
Score = 285 bits (728), Expect = 3e-79, Method: Composition-based stats.
Identities = 78/308 (25%), Positives = 142/308 (46%), Gaps = 21/308 (7%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
++ + ++ ++K +G G FG+V VA
Sbjct 591 MKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKRE-IYVA 649
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LKA + R + E I+ H +II+ +G + + ++ E++ G+L
Sbjct 650 IKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGALDS 707
Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
+L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++
Sbjct 708 FLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 767
Query 1047 AVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
+ + Y G PV W APE + KF ASDVWS+G+ ++E+++ +
Sbjct 768 YLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGER---- 823
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
M+ + +E+ RLP P CP ++ LM +CW+ + + RP
Sbjct 824 ----------PYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNTRPRLAE 873
Query 1165 LIPILKTV 1172
++ L +
Sbjct 874 IVNTLDKM 881
Score = 278 bits (711), Expect = 6e-77, Method: Composition-based stats.
Identities = 80/363 (22%), Positives = 139/363 (38%), Gaps = 46/363 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G VY+GRL++ G +E+ V +
Sbjct 612 KEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGK---------------------REIYVAI 650
Query 642 KVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L F AS+M Q H ++ + GV + +++TE++E+G LD +LR
Sbjct 651 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 710
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD
Sbjct 711 QNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVN-------SNLVCKVSDF 763
Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ +IP W APE + ++A D W +G + E+ G
Sbjct 764 GLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSFG 821
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P S + + ++ +RLP P CP L L C + RP I+ L ++
Sbjct 822 ERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNTRPRLAEIVNTLDKM 881
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG----E 925
+ + + S P + E V + Y G +
Sbjct 882 IRNPASLKTVATITAVPSQPLLDRSIPDFTAFTSVEDWLSAVKMSQYRDNFLSAGFTSLQ 941
Query 926 MVA 928
+VA
Sbjct 942 LVA 944
>sp|P51451|BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo sapiens
OX=9606 GN=BLK PE=1 SV=3
Length=505
Score = 272 bits (696), Expect = 4e-79, Method: Composition-based stats.
Identities = 79/403 (20%), Positives = 150/403 (37%), Gaps = 69/403 (17%)
Query 469 GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRE 528
G +LI S ++ L+V + + ++ + I D +FPS++
Sbjct 146 GSFLIRESETNKGAFSLSVKDVTTQGE-----LIKHYKIRCLDEGGYYISPRITFPSLQA 200
Query 529 LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKE 588
L C L C+ R +P+ + ++
Sbjct 201 LVQHYSKKG---DGLCQRLTLPCV---------------RPAPQNPWAQ--DEWEIPRQS 240
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+ + LG G V+ G + ++V +K L
Sbjct 241 LRLVRKLGSGQFGEVWMGYYKNN-------------------------MKVAIKTLKEGT 275
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVP 707
AF A++M + H L ++ V + +VTEY+ G L +L+ + G +
Sbjct 276 MSP-EAFLGEANVMKALQHERLVRLYAVVTK-EPIYIVTEYMARGCLLDFLKTDEGSRLS 333
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--- 764
+ + ++ Q+A ++Y+E N +H ++ NIL++ + K++D G+
Sbjct 334 LPRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSE-------ALCCKIADFGLARIID 386
Query 765 -GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
++E I W APE + G + D W FG L+E+ G P S E
Sbjct 387 SEYTAQEGAKFPIKWTAPEAIHFGV--FTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEV 444
Query 824 EHFYQRQHRL--PEPSCPQLAT-LTSQCLTYEPTQRPSFRTIL 863
+R +R+ P+ P+L + ++C P +RP+F +
Sbjct 445 IRNLERGYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEFLQ 487
Score = 268 bits (686), Expect = 9e-78, Method: Composition-based stats.
Identities = 97/315 (31%), Positives = 148/315 (47%), Gaps = 31/315 (10%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
Q L V + A D ++ L+ +R LG G FG+V + Y VA
Sbjct 213 CQRLTLPCVRPAPQNPWAQDEWEIPRQSLRLVRKLGSGQFGEVWMGYYK-----NNMKVA 267
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LK G + E ++++ L HE +++ ++ + +V EY+ G L D
Sbjct 268 IKTLKE--GTMSPEAFLGEANVMKALQHERLVRLYAVV---TKEPIYIVTEYMARGCLLD 322
Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L + L +L+ + QI EGMAY+ + IHRDL A N+L+ KI DFGLA
Sbjct 323 FLKTDEGSRLSLPRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLA 382
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + Y +E P+ W APE + F +DVWSFGV L E++T+
Sbjct 383 RII---DSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGR------ 433
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH-LMKNCWETEASFRPTFEN 1164
+ M+ + LERG R+PRPD CP E+Y ++ CW + RPTFE
Sbjct 434 --------VPYPGMSNPEVIRNLERGYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEF 485
Query 1165 LIPILKTVHEKYQGQ 1179
L +L+ + + Q
Sbjct 486 LQSVLEDFYTATERQ 500
>sp|P24604|TEC_MOUSE Tyrosine-protein kinase Tec OS=Mus musculus
OX=10090 GN=Tec PE=1 SV=2
Length=630
Score = 276 bits (706), Expect = 4e-79, Method: Composition-based stats.
Identities = 88/428 (21%), Positives = 159/428 (37%), Gaps = 66/428 (15%)
Query 460 VQAKLRPE--DGLYLIHWSTSHPYRLILTVAQR--SQAPDGMQSLRLRKFPIEQQDGAFV 515
+ LR E +G +++ S S P +++ + + G + +++ +
Sbjct 256 AEQLLRTEDKEGGFMVRDS-SQPGLYTVSLYTKFGGEGSSGFRHYHIKE--TATSPKKYY 312
Query 516 LEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLN 575
L +F S+ E+ + A LR + + +P T
Sbjct 313 L-AEKHAFGSIPEIIEYHKHN---AAGLVTRLRYP------------VSTKGKNAPTTAG 356
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
S ++ E+T + LG G V G+ R
Sbjct 357 FSY-DKWEINPSELTFMRELGSGLFGVVRLGKWRA------------------------- 390
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+ +V +K + F E A +M +++H L ++GVC + +VTE++E G L
Sbjct 391 QYKVAIKAIREGAM-CEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCL 449
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+LR+ +GH + + Q + + YLE + +H ++ RN L+ G+ +
Sbjct 450 LNFLRQRQGHFSRDMLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGV-------V 502
Query 756 KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K+SD G+ L + + W PE + S+ D W FG + EI +
Sbjct 503 KVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVF--NYSRFSSKSDVWSFGVLMWEIFTE 560
Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
G P + + E R HRL P+ + L + +C P RPS +LR +
Sbjct 561 GRMPFEKNTNYEVVTMVTRGHRLHRPKLATKYLYEVMLRCWQERPEGRPSLEDLLRTIDE 620
Query 869 LQPHNLAD 876
L
Sbjct 621 LVECEETF 628
Score = 254 bits (649), Expect = 2e-71, Method: Composition-based stats.
Identities = 86/292 (29%), Positives = 135/292 (46%), Gaps = 27/292 (9%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
+ D + L +R+LG G FG V L + VA+KA++ G +
Sbjct 357 FSYDKWEINPSELTFMRELGSGLFGVVRLGKWRAQYK-----VAIKAIRE--GAMCEEDF 409
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLL 1002
+E ++ L H +++ G C Q K + +V E++ G L ++L + LL
Sbjct 410 IEEAKVMMKLTHPKLVQLYGVCTQQ--KPIYIVTEFMERGCLLNFLRQRQGHFSRDMLLS 467
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
Q +CEGM YL +IHRDLAARN L++ +VK+ DFG+A+ V + + Y
Sbjct 468 MCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGVVKVSDFGMARYVLD--DQYTSSSGAK 525
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
PV W PE +F SDVWSFGV ++E+ T + + T
Sbjct 526 FPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTEGR--------------MPFEKNTNY 571
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ ++ RG RL RP +Y +M CW+ RP+ E+L+ + + E
Sbjct 572 EVVTMVTRGHRLHRPKLATKYLYEVMLRCWQERPEGRPSLEDLLRTIDELVE 623
>sp|Q90Z00|FGR1A_DANRE Fibroblast growth factor receptor 1-A OS=Danio
rerio OX=7955 GN=fgfr1a PE=1 SV=2
Length=810
Score = 281 bits (718), Expect = 4e-79, Method: Composition-based stats.
Identities = 102/312 (33%), Positives = 154/312 (49%), Gaps = 38/312 (12%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---EMVAVKALKADCG 937
+ P + L + LGEG FG+V + + VAVK LK+D
Sbjct 449 EYELPQDPRWEVQRDRLVLGKPLGEGCFGQVMMAEAMGMDKEKPNRITKVAVKMLKSDAT 508
Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990
+ S E+++++ + H++II G C G L +++E+ G+LR+YL
Sbjct 509 EKDLSDLISEMEMMKIIGKHKNIINLLGACTQDG--PLYVIVEFAAKGNLREYLRVRRPP 566
Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
P ++ + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI
Sbjct 567 GMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKI 626
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T
Sbjct 627 ADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--- 682
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L G + V L +LL+ G R+ RP C E+Y +M++CW S R
Sbjct 683 -----------LGGSPYPGVPVEELFKLLKEGHRMDRPSTCTHELYMMMRDCWHAVPSQR 731
Query 1160 PTFENLIPILKT 1171
PTF+ L+ L
Sbjct 732 PTFKQLVEDLDR 743
Score = 233 bits (594), Expect = 1e-62, Method: Composition-based stats.
Identities = 63/316 (20%), Positives = 113/316 (36%), Gaps = 51/316 (16%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
L Q V + + LG+G V M E +
Sbjct 448 SEYELPQDPRWEVQRDRLVLGKPLGEGCFGQV-----------------MMAEAMGMDKE 490
Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689
+ +V +K+L + L +M + H ++ + G C + ++ E+
Sbjct 491 KPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEF 550
Query 690 VEHGPLDVWLRRERG---------------HVPMAWKMVVAQQLASALSYLENKNLVHGN 734
G L +LR R ++ + + A Q+A + YL +K +H +
Sbjct 551 AAKGNLREYLRVRRPPGMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRD 610
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788
+ RN+L+ + +K++D G+ ++ R+P W+APE L
Sbjct 611 LAARNVLVTEDNV-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRI 663
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846
+ D W FG L EI G +P E + HR+ P +L +
Sbjct 664 --YTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDRPSTCTHELYMMMR 721
Query 847 QCLTYEPTQRPSFRTI 862
C P+QRP+F+ +
Sbjct 722 DCWHAVPSQRPTFKQL 737
>sp|P27450|CST_ARATH Probable serine/threonine-protein kinase
CST OS=Arabidopsis thaliana OX=3702 GN=CST PE=1 SV=2
Length=419
Score = 269 bits (688), Expect = 4e-79, Method: Composition-based stats.
Identities = 80/282 (28%), Positives = 139/282 (49%), Gaps = 15/282 (5%)
Query 903 LGEGHFGKVSLYCYDPT-----NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LG+G FGKV D T G+G +VA+K L ++ Q + W+ E++ L L H
Sbjct 92 LGQGGFGKVYRGWVDATTLAPSRVGSGMIVAIKRLNSE-SVQGFAEWRSEVNFLGMLSHR 150
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLH 1015
+++K G C + +K L LV E++P GSL +L R + G+A+LH
Sbjct 151 NLVKLLGYCRE--DKELLLVYEFMPKGSLESHLFRRNDPFPWDLRIKIVIGAARGLAFLH 208
Query 1016 A--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ + I+RD A N+LLD++ K+ DFGLAK P + + V + APE +
Sbjct 209 SLQREVIYRDFKASNILLDSNYDAKLSDFGLAKLGPADEKSH-VTTRIMGTYGYAAPEYM 267
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVL-RLTELLERG 1131
Y SDV++FGV L E++T + P L+ + +++ R+ +++++G
Sbjct 268 ATGHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLVDWLRPELSNKHRVKQIMDKG 327
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ K E+ + +C E + RP + ++ +L+ +
Sbjct 328 IKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEVLEHIQ 369
Score = 245 bits (625), Expect = 2e-70, Method: Composition-based stats.
Identities = 83/395 (21%), Positives = 140/395 (35%), Gaps = 60/395 (15%)
Query 554 QPGETSNLIIM-RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
Q + S II G L + + K S LGQG VY G +
Sbjct 50 QFSDISTGIISDSGKLLESPNLKVYNFLDLKTATKNFKPDSMLGQGGFGKVYRGWV---- 105
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672
D L P R G + V +K L+ + + + +SH +L
Sbjct 106 ----------DATTLAPSR-VGSGMIVAIKRLNSESVQGFAEWRSEVNFLGMLSHRNLVK 154
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN--KNL 730
+ G C E ++V E++ G L+ L R P ++ + A L++L + + +
Sbjct 155 LLGYCREDKELLLVYEFMPKGSLESHLFRRNDPFPWDLRIKIVIGAARGLAFLHSLQREV 214
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECL 784
++ + NILL ++ KLSD G+ + E+ + + APE +
Sbjct 215 IYRDFKASNILLD-------SNYDAKLSDFGLAKLGPADEKSHVTTRIMGTYGYAAPEYM 267
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-------QHRLPEPS 837
G L D + FG LLEI G ++ P +E +HR+ +
Sbjct 268 ATG--HLYVKSDVFAFGVVLLEIM-TGLTAHNTKRPRGQESLVDWLRPELSNKHRVKQIM 324
Query 838 C------------PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885
++A +T C+ +P RP + ++ L +Q N+ + +
Sbjct 325 DKGIKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEVLEHIQGLNVVPNRSSTKQAV 384
Query 886 ASDPTVFHKRYLKKIRDL-------GEGHFGKVSL 913
A+ Y K L G FG V
Sbjct 385 ANSSRSSPHHYRYKAGALGAERKRATPGRFGSVEK 419
>sp|Q5XF79|PBL18_ARATH Probable serine/threonine-protein kinase
PBL18 OS=Arabidopsis thaliana OX=3702 GN=PBL18 PE=2 SV=1
Length=387
Score = 268 bits (685), Expect = 5e-79, Method: Composition-based stats.
Identities = 94/331 (28%), Positives = 142/331 (43%), Gaps = 14/331 (4%)
Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVS 912
P+ + T + + + + R K +GEG FG V
Sbjct 40 PSYSNNSFTTSSWSNLTPRSEGELLPSPTLKAFTFNELKTATRNFKPNSMIGEGGFGCVY 99
Query 913 LYC-----YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
P+ G+G +VAVK LK++ G Q W E+ L L+H +++K G C
Sbjct 100 KGWIGERSLSPSKPGSGMVVAVKKLKSE-GFQGHKEWLTEVHYLGRLHHMNLVKLIGYCL 158
Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQHYIHRDL 1024
+ GEK L LV EY+P GSL ++L R I + A G+++LH I+RD
Sbjct 159 E-GEKRL-LVYEYMPKGSLENHLFRRGAEPIPWKTRMKVAFSAARGLSFLHEAKVIYRDF 216
Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084
A N+LLD D K+ DFGLAKA P G + V + APE + + SDV
Sbjct 217 KASNILLDVDFNAKLSDFGLAKAGPTGDRTH-VTTQVIGTQGYAAPEYIATGRLTSKSDV 275
Query 1085 WSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQMTVLR-LTELLERGERLPRPDKCPC 1142
+SFGV L ELL+ + L+ A + R + +++ P K C
Sbjct 276 YSFGVVLLELLSGRPTLDKSKVGVERNLVDWAIPYLVDRRKVFRIMDTKLGGQYPHKGAC 335
Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
++ C TE RP +++ L+ +
Sbjct 336 AAANIALRCLNTEPKLRPDMADVLSTLQQLE 366
Score = 239 bits (611), Expect = 7e-69, Method: Composition-based stats.
Identities = 75/361 (21%), Positives = 124/361 (34%), Gaps = 50/361 (14%)
Query 556 GETSNL-IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
SNL G TL + + + S +G+G VY+G +
Sbjct 50 SSWSNLTPRSEGELLPSPTLKAFTFNELKTATRNFKPNSMIGEGGFGCVYKGWIG----- 104
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
E L P + G + V +K L + + ++ H +L +
Sbjct 105 ---------ERSLSPSKP-GSGMVVAVKKLKSEGFQGHKEWLTEVHYLGRLHHMNLVKLI 154
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHG 733
G C+ G + ++V EY+ G L+ L R +P +M VA A LS+L +++
Sbjct 155 GYCLEGEKRLLVYEYMPKGSLENHLFRRGAEPIPWKTRMKVAFSAARGLSFLHEAKVIYR 214
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGG 787
+ NILL KLSD G+ + + + + APE + G
Sbjct 215 DFKASNILLD-------VDFNAKLSDFGLAKAGPTGDRTHVTTQVIGTQGYAAPEYIATG 267
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR------------------ 829
L++ D + FG LLE+ +S+ E+
Sbjct 268 --RLTSKSDVYSFGVVLLELLSGRPTLDKSKVGVERNLVDWAIPYLVDRRKVFRIMDTKL 325
Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
+ P A + +CL EP RP +L L +L+ + T N S
Sbjct 326 GGQYPHKGACAAANIALRCLNTEPKLRPDMADVLSTLQQLETSSKKMGSTQNIVMSPSSH 385
Query 890 T 890
Sbjct 386 M 386
>sp|P41239|CSK_CHICK Tyrosine-protein kinase CSK OS=Gallus gallus
OX=9031 GN=CSK PE=2 SV=1
Length=450
Score = 270 bits (691), Expect = 5e-79, Method: Composition-based stats.
Identities = 102/323 (32%), Positives = 154/323 (48%), Gaps = 33/323 (10%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915
+RL + + D + + + LK ++ +G+G FG V L
Sbjct 154 EHYTTDADGLCSRLIKPKVMEGTVAAQDEFSRSGWALNMKDLKLLQIIGKGEFGDVMLGD 213
Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
Y G VAVK +K D Q + E ++ L H ++++ G ++ + L
Sbjct 214 YR------GNKVAVKCIKNDATAQ---AFLAEASVMTQLRHSNLVQLLGVIVEE-KSGLY 263
Query 976 LVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032
+V EY+ GSL DYL R +G LL F+ +CE M YL A +++HRDLAARNVL+
Sbjct 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEANNFVHRDLAARNVLVS 323
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
D + K+ DFGL K E ++ G PV W APE L+E KF SDVWSFG+ L+
Sbjct 324 EDNIAKVSDFGLTK------EASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLW 377
Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152
E+ + + ++ + + +E+G ++ PD CP VY +MK CW
Sbjct 378 EIYSFGR--------------VPYPRIPLKDVVPRVEKGYKMDPPDGCPAIVYEVMKKCW 423
Query 1153 ETEASFRPTFENLIPILKTVHEK 1175
+ RP+F L L + EK
Sbjct 424 TLDPGHRPSFHQLREQLVHIKEK 446
Score = 260 bits (665), Expect = 2e-75, Method: Composition-based stats.
Identities = 100/431 (23%), Positives = 168/431 (39%), Gaps = 70/431 (16%)
Query 446 SIRDGIHGPLLEPFVQAKLRP-EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
S+ HG + + L P E GL+L+ ST++P L V+ + K
Sbjct 78 SLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIIYSSSK 137
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
I+++ F ++ +L A C L + +M
Sbjct 138 LSIDEE----------VYFENLMQLVEHYTTD---ADGLCSRLIKP-----------KVM 173
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
G A+ + S ++ K++ L +G+G +V G R
Sbjct 174 EGTVAAQDEFSRSG---WALNMKDLKLLQIIGKGEFGDVMLGDYRGN------------- 217
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE-N 683
+V +K + A AF AS+M+Q+ H++L + GV V
Sbjct 218 -------------KVAVKCIKNDAT--AQAFLAEASVMTQLRHSNLVQLLGVIVEEKSGL 262
Query 684 IMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+VTEY+ G L +LR R R + + + + A+ YLE N VH ++ RN+L+
Sbjct 263 YIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEANNFVHRDLAARNVLV 322
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFG 801
+ +A K+SD G+ A S ++ + + W APE L ST D W FG
Sbjct 323 SEDNIA-------KVSDFGLTKEASSTQDTGKLPVKWTAPEALRE--KKFSTKSDVWSFG 373
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQL-ATLTSQCLTYEPTQRPSF 859
L EI G P + ++ +++ P CP + + +C T +P RPSF
Sbjct 374 ILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDPPDGCPAIVYEVMKKCWTLDPGHRPSF 433
Query 860 RTILRDLTRLQ 870
+ L ++
Sbjct 434 HQLREQLVHIK 444
>sp|Q07497|EPHB5_CHICK Ephrin type-B receptor 5 OS=Gallus gallus
OX=9031 GN=EPHB5 PE=2 SV=1
Length=1002
Score = 284 bits (727), Expect = 5e-79, Method: Composition-based stats.
Identities = 81/331 (24%), Positives = 150/331 (45%), Gaps = 23/331 (7%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
P + I ++ + ++ ++K +G G FG
Sbjct 590 RETPYTDRLQQYISTRGLGVKYYIDPSTYEDPNEAIREFAKEIDVSFIKIEEVIGSGEFG 649
Query 910 KVSLYCYDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968
+V + G E VA+K LK+ + R + E I+ H ++I +G
Sbjct 650 EVCFGRLK--HPGKREYTVAIKTLKSGYTDEQRREFLSEASIMGQFEHPNVIHLEGVVTK 707
Query 969 QGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
+ + +V E++ GSL +L + + QL+ + I GM YL +Y+HRDLAA
Sbjct 708 S--RPVMIVTEFMENGSLDSFLRQKEGQFSVLQLVGMLRGIAAGMRYLSDMNYVHRDLAA 765
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPE--GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084
RN+L++++ + K+ DFGL++ + + + Y P+ W APE ++ KF +SDV
Sbjct 766 RNILVNSNLVCKVSDFGLSRFLEDDASNPTYTGALGCKIPIRWTAPEAVQYRKFTSSSDV 825
Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144
WS+G+ ++E++++ + M+ + +++ RLP P CP +
Sbjct 826 WSYGIVMWEVMSYGER--------------PYWDMSNQDVINAIDQDYRLPPPPDCPTVL 871
Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+ LM +CW+ + RP FE ++ L + K
Sbjct 872 HLLMLDCWQKDRVQRPKFEQIVSALDKMIRK 902
Score = 270 bits (689), Expect = 5e-74, Method: Composition-based stats.
Identities = 81/348 (23%), Positives = 134/348 (39%), Gaps = 42/348 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D I +G G V GRL+ G +E V +
Sbjct 630 KEIDVSFIKIEEVIGSGEFGEVCFGRLKHPGK---------------------REYTVAI 668
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + D F AS+M Q H ++ + GV + ++VTE++E+G LD +LR
Sbjct 669 KTLKSGYTDEQRREFLSEASIMGQFEHPNVIHLEGVVTKSRPVMIVTEFMENGSLDSFLR 728
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
++ G + + + + +A+ + YL + N VH ++ RNIL+ ++ K+SD
Sbjct 729 QKEGQFSVLQLVGMLRGIAAGMRYLSDMNYVHRDLAARNILVN-------SNLVCKVSDF 781
Query 761 GVGL---GALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ S I W APE + +++ D W +G + E+ G
Sbjct 782 GLSRFLEDDASNPTYTGALGCKIPIRWTAPEAVQ--YRKFTSSSDVWSYGIVMWEVMSYG 839
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P S + + + +RLP P CP L L C + QRP F I+ L ++
Sbjct 840 ERPYWDMSNQDVINAIDQDYRLPPPPDCPTVLHLLMLDCWQKDRVQRPKFEQIVSALDKM 899
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917
A T S S P + + + + Y
Sbjct 900 IRKPSALKATGTGSSRPSQPLLSNSPPDFPSLSNAHEWLDAIKMGRYK 947
>sp|Q6VNS1|NTRK3_MOUSE NT-3 growth factor receptor OS=Mus musculus
OX=10090 GN=Ntrk3 PE=1 SV=1
Length=825
Score = 281 bits (718), Expect = 6e-79, Method: Composition-based stats.
Identities = 114/335 (34%), Positives = 160/335 (48%), Gaps = 36/335 (11%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914
P I + + N P + +R + R+LGEG FGKV L
Sbjct 497 GPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAE 556
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
CY+ + +VAVKALK D R +++E ++L L HEHI+K+ G C D L
Sbjct 557 CYNLSPTKDKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PL 613
Query 975 QLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQ 1017
+V EY+ G L +L H +GL+Q+L A QI GM YL +Q
Sbjct 614 IMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQ 673
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
H++HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + K
Sbjct 674 HFVHRDLATRNCLVGANLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRK 732
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFGV L+E+ T+ Q++ + E + +G L RP
Sbjct 733 FTTESDVWSFGVILWEIFTYGKQ--------------PWFQLSNTEVIECITQGRVLERP 778
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
CP EVY +M CW+ E R + + IL +
Sbjct 779 RVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813
Score = 263 bits (673), Expect = 5e-73, Method: Composition-based stats.
Identities = 73/309 (24%), Positives = 126/309 (41%), Gaps = 51/309 (17%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ +++I LG+G V+ + + L P +D+ + V +K
Sbjct 533 IKRRDIVLKRELGEGAFGKVF----------------LAECYNLSPTKDK---MLVAVKA 573
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702
L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR
Sbjct 574 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633
Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+G + ++ + +A Q+AS + YL +++ VH ++ RN L+
Sbjct 634 PDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV------ 687
Query 749 EGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
G + +K+ D G+ S + + I W+ PE + +T D W FG
Sbjct 688 -GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGV 744
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860
L EI G+ P S +E + L P ++ + C EP QR + +
Sbjct 745 ILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIK 804
Query 861 TILRDLTRL 869
I + L L
Sbjct 805 EIYKILHAL 813
>sp|Q91044|NTRK3_CHICK NT-3 growth factor receptor OS=Gallus gallus
OX=9031 GN=NTRK3 PE=1 SV=2
Length=827
Score = 281 bits (718), Expect = 6e-79, Method: Composition-based stats.
Identities = 114/335 (34%), Positives = 160/335 (48%), Gaps = 36/335 (11%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914
P I + + N P + +R + R+LGEG FGKV L
Sbjct 499 GPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAE 558
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
CY+ + +VAVKALK D R +++E ++L L HEHI+K+ G C D L
Sbjct 559 CYNLSPTNDKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PL 615
Query 975 QLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQ 1017
+V EY+ G L +L H +GL+Q+L A QI GM YL +Q
Sbjct 616 IMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQ 675
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
H++HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + K
Sbjct 676 HFVHRDLATRNCLVGANLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRK 734
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFGV L+E+ T+ Q++ + E + +G L RP
Sbjct 735 FTTESDVWSFGVILWEIFTYGKQ--------------PWFQLSNTEVIECITQGRVLERP 780
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
CP EVY +M CW+ E R + + IL +
Sbjct 781 RVCPKEVYDIMLGCWQREPQQRLNIKEIYKILHAL 815
Score = 263 bits (672), Expect = 9e-73, Method: Composition-based stats.
Identities = 73/309 (24%), Positives = 125/309 (40%), Gaps = 51/309 (17%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ +++I LG+G V+ + + L P D+ + V +K
Sbjct 535 IKRRDIVLKRELGEGAFGKVF----------------LAECYNLSPTNDK---MLVAVKA 575
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702
L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR
Sbjct 576 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 635
Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+G + ++ + +A Q+AS + YL +++ VH ++ RN L+
Sbjct 636 PDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV------ 689
Query 749 EGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
G + +K+ D G+ S + + I W+ PE + +T D W FG
Sbjct 690 -GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGV 746
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860
L EI G+ P S +E + L P ++ + C EP QR + +
Sbjct 747 ILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDIMLGCWQREPQQRLNIK 806
Query 861 TILRDLTRL 869
I + L L
Sbjct 807 EIYKILHAL 815
>sp|P29322|EPHA8_HUMAN Ephrin type-A receptor 8 OS=Homo sapiens
OX=9606 GN=EPHA8 PE=1 SV=2
Length=1005
Score = 284 bits (726), Expect = 7e-79, Method: Composition-based stats.
Identities = 90/321 (28%), Positives = 143/321 (45%), Gaps = 20/321 (6%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
Q + + S + + +G G G+V VA+
Sbjct 608 QFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRD-VPVAI 666
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
KALKA + R + E I+ H +II+ +G + +V EY+ GSL +
Sbjct 667 KALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRG--RLAMIVTEYMENGSLDTF 724
Query 990 LPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
L H + QL+ + + GM YL Y+HRDLAARNVL+D++ + K+ DFGL++
Sbjct 725 LRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRV 784
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ + + G P+ W APE + F ASDVWSFGV ++E+L + +
Sbjct 785 LEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGER------- 837
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
MT + +E G RLP P CP ++ LM +CW + + RP F ++
Sbjct 838 -------PYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVS 890
Query 1168 ILKTVHEKYQG-QAPSVFSVC 1187
+L + + +A + S C
Sbjct 891 VLDALIRSPESLRATATVSRC 911
Score = 259 bits (662), Expect = 2e-70, Method: Composition-based stats.
Identities = 78/325 (24%), Positives = 126/325 (39%), Gaps = 40/325 (12%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
++ I +G G V GRLRV G +++ V
Sbjct 627 TREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQ---------------------RDVPVA 665
Query 641 LKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+K L + + F AS+M Q H ++ + GV RG ++VTEY+E+G LD +L
Sbjct 666 IKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFL 725
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R G + + + + + + + YL + VH ++ RN+L+ ++ K+SD
Sbjct 726 RTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVD-------SNLVCKVSD 778
Query 760 PGVGL-------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
G+ A + I W APE + + S+A D W FG + E+ GE
Sbjct 779 FGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIA--FRTFSSASDVWSFGVVMWEVLAYGE 836
Query 813 APLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P + + + + +RLP CP L L C + QRP F I+ L L
Sbjct 837 RPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALI 896
Query 871 PHNLADVLTVNPDSPASDPTVFHKR 895
+ T V
Sbjct 897 RSPESLRATATVSRCPPPAFVRSCF 921
>sp|Q91987|NTRK2_CHICK BDNF/NT-3 growth factors receptor OS=Gallus
gallus OX=9031 GN=NTRK2 PE=1 SV=1
Length=818
Score = 280 bits (716), Expect = 8e-79, Method: Composition-based stats.
Identities = 109/334 (33%), Positives = 159/334 (48%), Gaps = 33/334 (10%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914
P I + + +T + P + + + R+LGEG FGKV L
Sbjct 493 GPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAE 552
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
CY+ + +VAVK LK D R + +E ++L L HEHI+K+ G C + L
Sbjct 553 CYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGD--PL 609
Query 975 QLVMEYVPLGSLRDYLPRHS--------------IGLAQLLLFAQQICEGMAYLHAQHYI 1020
+V EY+ G L +L H + +Q+L AQQI GM YL +QH++
Sbjct 610 IMVFEYMKHGDLNKFLRAHGPDAVLMAEGNRPAELTQSQMLHIAQQIAAGMVYLASQHFV 669
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + KF
Sbjct 670 HRDLATRNCLVGENLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRKFTT 728
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS GV L+E+ T+ Q++ + E + +G L RP C
Sbjct 729 ESDVWSLGVVLWEIFTYGKQ--------------PWYQLSNNEVIECITQGRVLQRPRTC 774
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
P EVY LM CW+ E R + + +L+ + +
Sbjct 775 PKEVYDLMLGCWQREPHMRLNIKEIHSLLQNLAK 808
Score = 266 bits (681), Expect = 4e-74, Method: Composition-based stats.
Identities = 72/306 (24%), Positives = 123/306 (40%), Gaps = 48/306 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ + I LG+G V+ + + L P +D+ + V +K
Sbjct 529 IKRHNIVLKRELGEGAFGKVF----------------LAECYNLCPEQDK---ILVAVKT 569
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--- 700
L + + F+ A L++ + H H+ +GVCV G IMV EY++HG L+ +LR
Sbjct 570 LKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 629
Query 701 ---------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
+ + + +AQQ+A+ + YL +++ VH ++ RN L+ G
Sbjct 630 PDAVLMAEGNRPAELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV-------GE 682
Query 752 SPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ +K+ D G+ S + + I W+ PE + +T D W G L
Sbjct 683 NLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSLGVVLW 740
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
EI G+ P S +E + L P ++ L C EP R + + I
Sbjct 741 EIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPKEVYDLMLGCWQREPHMRLNIKEIH 800
Query 864 RDLTRL 869
L L
Sbjct 801 SLLQNL 806
>sp|Q5IFJ9|NTRK3_MACFA NT-3 growth factor receptor OS=Macaca fascicularis
OX=9541 GN=NTRK3 PE=2 SV=1
Length=825
Score = 280 bits (717), Expect = 9e-79, Method: Composition-based stats.
Identities = 114/335 (34%), Positives = 160/335 (48%), Gaps = 36/335 (11%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914
P I + + N P + +R + R+LGEG FGKV L
Sbjct 497 GPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAE 556
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
CY+ + +VAVKALK D R +++E ++L L HEHI+K+ G C D L
Sbjct 557 CYNLSPTKDKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PL 613
Query 975 QLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQ 1017
+V EY+ G L +L H +GL+Q+L A QI GM YL +Q
Sbjct 614 IMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQ 673
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
H++HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + K
Sbjct 674 HFVHRDLATRNCLVGANLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRK 732
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFGV L+E+ T+ Q++ + E + +G L RP
Sbjct 733 FTTESDVWSFGVILWEIFTYGKQ--------------PWFQLSNTEVIECITQGRVLERP 778
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
CP EVY +M CW+ E R + + IL +
Sbjct 779 RVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813
Score = 263 bits (672), Expect = 8e-73, Method: Composition-based stats.
Identities = 73/309 (24%), Positives = 126/309 (41%), Gaps = 51/309 (17%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ +++I LG+G V+ + + L P +D+ + V +K
Sbjct 533 IKRRDIVLKRELGEGAFGKVF----------------LAECYNLSPTKDK---MLVAVKA 573
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702
L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR
Sbjct 574 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633
Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+G + ++ + +A Q+AS + YL +++ VH ++ RN L+
Sbjct 634 PDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV------ 687
Query 749 EGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
G + +K+ D G+ S + + I W+ PE + +T D W FG
Sbjct 688 -GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGV 744
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860
L EI G+ P S +E + L P ++ + C EP QR + +
Sbjct 745 ILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIK 804
Query 861 TILRDLTRL 869
I + L L
Sbjct 805 EIYKILHAL 813
>sp|Q5IS37|NTRK3_PANTR NT-3 growth factor receptor OS=Pan troglodytes
OX=9598 GN=NTRK3 PE=2 SV=1
Length=825
Score = 280 bits (717), Expect = 9e-79, Method: Composition-based stats.
Identities = 114/335 (34%), Positives = 160/335 (48%), Gaps = 36/335 (11%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914
P I + + N P + +R + R+LGEG FGKV L
Sbjct 497 GPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAE 556
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
CY+ + +VAVKALK D R +++E ++L L HEHI+K+ G C D L
Sbjct 557 CYNLSPTKDKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PL 613
Query 975 QLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQ 1017
+V EY+ G L +L H +GL+Q+L A QI GM YL +Q
Sbjct 614 IMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQ 673
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
H++HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + K
Sbjct 674 HFVHRDLATRNCLVGANLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRK 732
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFGV L+E+ T+ Q++ + E + +G L RP
Sbjct 733 FTTESDVWSFGVILWEIFTYGKQ--------------PWFQLSNTEVIECITQGRVLERP 778
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
CP EVY +M CW+ E R + + IL +
Sbjct 779 RVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813
Score = 263 bits (672), Expect = 8e-73, Method: Composition-based stats.
Identities = 73/309 (24%), Positives = 126/309 (41%), Gaps = 51/309 (17%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ +++I LG+G V+ + + L P +D+ + V +K
Sbjct 533 IKRRDIVLKRELGEGAFGKVF----------------LAECYNLSPTKDK---MLVAVKA 573
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702
L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR
Sbjct 574 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633
Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+G + ++ + +A Q+AS + YL +++ VH ++ RN L+
Sbjct 634 PDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV------ 687
Query 749 EGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
G + +K+ D G+ S + + I W+ PE + +T D W FG
Sbjct 688 -GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGV 744
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860
L EI G+ P S +E + L P ++ + C EP QR + +
Sbjct 745 ILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIK 804
Query 861 TILRDLTRL 869
I + L L
Sbjct 805 EIYKILHAL 813
>sp|Q54H45|DRKB_DICDI Probable serine/threonine-protein kinase
drkB OS=Dictyostelium discoideum OX=44689 GN=drkB PE=3 SV=1
Length=690
Score = 277 bits (708), Expect = 1e-78, Method: Composition-based stats.
Identities = 79/286 (28%), Positives = 129/286 (45%), Gaps = 34/286 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHII 960
+G+G+FG+V L + G VAVK L A + + +EI++++ L H ++I
Sbjct 396 RIGKGNFGEVYLGTWR------GSQVAVKKLPAHNINENILKEFHREINLMKNLRHPNVI 449
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI--GLAQLLLFAQQICEGMAYLHAQH 1018
++ G C + + + EY+P GSL L I + + +G+ YLH
Sbjct 450 QFLGSCLISPD--ICICTEYMPRGSLYSILHNEKIKISWSLVKRMMIDAAKGIIYLHGST 507
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL + N+L+D + VK+ DFGL+ +G W +PE L+
Sbjct 508 PVILHRDLKSHNLLVDENWKVKVADFGLSTIEQQG-----ATMTACGTPCWTSPEVLRSQ 562
Query 1077 KFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
++ +DV+SFG+ L+E T D PP + + +G G R P
Sbjct 563 RYTEKADVYSFGIILWECATRQDPYFGIPPFQVIFAVG---------------REGMRPP 607
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
P P + L+K+C S RPT E + IL+++ K P
Sbjct 608 TPKYGPPKYIQLLKDCLNENPSQRPTMEQCLEILESIETKGFDDIP 653
Score = 236 bits (602), Expect = 2e-64, Method: Composition-based stats.
Identities = 60/308 (19%), Positives = 108/308 (35%), Gaps = 45/308 (15%)
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
+R S R+ +D ++I +G+G VY G R
Sbjct 366 IRKRLNSKRSGYTQIKDGKDIDTQQIKIGVRIGKGNFGEVYLGTWRGS------------ 413
Query 624 EDPLVPGRDRGQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
+V +K L + +I F+ +LM + H ++ G C+ P
Sbjct 414 --------------QVAVKKLPAHNINENILKEFHREINLMKNLRHPNVIQFLGSCLISP 459
Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRN 739
+ + TEY+ G L L E+ + + + A + YL ++H ++ N
Sbjct 460 DICICTEYMPRGSLYSILHNEKIKISWSLVKRMMIDAAKGIIYLHGSTPVILHRDLKSHN 519
Query 740 ILLARLGLAEGTSPFIKLSDPGVGL--GALSREERVERIPWLAPECLPGGANSLSTAMDK 797
+L+ + +K++D G+ + W +PE L + + D
Sbjct 520 LLVDE-------NWKVKVADFGLSTIEQQGATMTACGTPCWTSPEVLR--SQRYTEKADV 570
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---QHRLPEPSCPQLATLTSQCLTYEPT 854
+ FG L E C + P P + R + P+ P+ L CL P+
Sbjct 571 YSFGIILWE-CATRQDPYFGIPPFQVIFAVGREGMRPPTPKYGPPKYIQLLKDCLNENPS 629
Query 855 QRPSFRTI 862
QRP+
Sbjct 630 QRPTMEQC 637
>sp|P54754|EPHB3_MOUSE Ephrin type-B receptor 3 OS=Mus musculus
OX=10090 GN=Ephb3 PE=1 SV=2
Length=993
Score = 283 bits (724), Expect = 1e-78, Method: Composition-based stats.
Identities = 84/355 (24%), Positives = 150/355 (42%), Gaps = 29/355 (8%)
Query 844 LTSQCLTYE---PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+ CL + P + + ++ + ++ +K
Sbjct 572 IALVCLRKQRHGPDAEYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIE 631
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G FG+V VA+K LK + R + E I+ H +II
Sbjct 632 EVIGAGEFGEVCRGRLKLPGRRE-VFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNII 690
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ +G + + ++ E++ +L +L + QL+ + I GM YL +
Sbjct 691 RLEGVVTKS--RPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMN 748
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076
Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G P+ W APE +
Sbjct 749 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYR 808
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
KF ASDVWS+G+ ++E++++ + M+ + +E+ RLP
Sbjct 809 KFTSASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVINAVEQDYRLPP 854
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE-----KYQGQAPSVFSV 1186
P CP ++ LM +CW + + RP F ++ L + K APS S
Sbjct 855 PMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVTASAPSGMSQ 909
Score = 262 bits (669), Expect = 2e-71, Method: Composition-based stats.
Identities = 81/363 (22%), Positives = 142/363 (39%), Gaps = 46/363 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G V GRL++ G +E+ V +
Sbjct 621 KEIDVSCVKIEEVIGAGEFGEVCRGRLKLPGR---------------------REVFVAI 659
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + +++TE++E+ LD +LR
Sbjct 660 KTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLR 719
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD
Sbjct 720 LNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 772
Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ +IP W APE + ++A D W +G + E+ G
Sbjct 773 GLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYG 830
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P S + + ++ +RLP P CP L L C + RP F I+ L +L
Sbjct 831 ERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKL 890
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG----E 925
+ + +T + S S P + + + Y + G G +
Sbjct 891 IRNAASLKVTASAPSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVGAGFASFD 950
Query 926 MVA 928
+VA
Sbjct 951 LVA 953
>sp|Q86PM4|FGFR_HYDVU Fibroblast growth factor receptor OS=Hydra
vulgaris OX=6087 GN=FGFR PE=2 SV=1
Length=816
Score = 280 bits (715), Expect = 1e-78, Method: Composition-based stats.
Identities = 107/333 (32%), Positives = 159/333 (48%), Gaps = 31/333 (9%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
T + R L + + D +N L+ LGEG FG+V
Sbjct 431 TSVSASYASRRFRHSLNNNLINDKQKLNLKIAPDPAWEIKLEQLETDCLLGEGAFGRVFR 490
Query 914 YCYDPTNDGTG-EMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGE 971
+ TG + VAVK LK DC Q + EI++++++ H +I+ QG+
Sbjct 491 ATARDLPNHTGVQTVAVKMLKEDCCEQDLKDFISEIEVMKSIGKHINILNLLAVSSQQGK 550
Query 972 KSLQLVMEYVPLGSLRDYLPRH------------SIGLAQLLLFAQQICEGMAYLHAQHY 1019
L +V+EY G+LR +L + I L L F Q+ GM +L ++
Sbjct 551 --LYIVVEYCRHGNLRSFLKDNRPVMQANSVITKKITLYDLTSFCLQVARGMNFLASKKC 608
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+AARNVL+ L+KI DFGLA+ + E +YYR DG PV W A E L + +
Sbjct 609 IHRDIAARNVLVGEGYLMKIADFGLARDIHE-QDYYRKCTDGRLPVKWMAIEALFDRVYT 667
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SD+WSFG+ +E++T G + + +L +LL++G R+ RP
Sbjct 668 TQSDIWSFGILAWEIVTFG--------------GSPYPGIALEKLFDLLKQGYRMERPLN 713
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
C ++Y LM NCW+ S RPTF LI L+ +
Sbjct 714 CTDDMYTLMLNCWKEIPSKRPTFSQLIEDLERM 746
Score = 220 bits (561), Expect = 2e-58, Method: Composition-based stats.
Identities = 57/308 (19%), Positives = 113/308 (37%), Gaps = 48/308 (16%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ +++ LG+G V+ R + + V +
Sbjct 467 WEIKLEQLETDCLLGEGAFGRVFRATARDLPNHTGVQ-------------------TVAV 507
Query 642 KVLDPSH-HDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
K+L F +M + H ++ + V + + +V EY HG L +L
Sbjct 508 KMLKEDCCEQDLKDFISEIEVMKSIGKHINILNLLAVSSQQGKLYIVVEYCRHGNLRSFL 567
Query 700 RRER----------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
+ R + + Q+A +++L +K +H ++ RN+L+ L
Sbjct 568 KDNRPVMQANSVITKKITLYDLTSFCLQVARGMNFLASKKCIHRDIAARNVLVGEGYL-- 625
Query 750 GTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+K++D G+ ++ + + W+A E L +T D W FG
Sbjct 626 -----MKIADFGLARDIHEQDYYRKCTDGRLPVKWMAIEALFDRV--YTTQSDIWSFGIL 678
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRT 861
EI G +P + + ++ +R+ P + TL C P++RP+F
Sbjct 679 AWEIVTFGGSPYPGIALEKLFDLLKQGYRMERPLNCTDDMYTLMLNCWKEIPSKRPTFSQ 738
Query 862 ILRDLTRL 869
++ DL R+
Sbjct 739 LIEDLERM 746
>sp|Q3UFB7|NTRK1_MOUSE High affinity nerve growth factor receptor
OS=Mus musculus OX=10090 GN=Ntrk1 PE=1 SV=2
Length=799
Score = 278 bits (712), Expect = 2e-78, Method: Composition-based stats.
Identities = 102/316 (32%), Positives = 157/316 (50%), Gaps = 35/316 (11%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKA 934
++ + ++ + +LGEG FGKV L CY+ ND +VAVKALK
Sbjct 492 HIMENPQYFSDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALK- 550
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993
+ R +++E ++L L H+HI+++ G C + G L +V EY+ G L +L H
Sbjct 551 EASENARQDFQREAELLTMLQHQHIVRFFGVCTEGG--PLLMVFEYMRHGDLNRFLRSHG 608
Query 994 ---------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
+GL QLL A Q+ GM YL + H++HRDLA RN L+ +VK
Sbjct 609 PDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVK 668
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
IGDFG+++ + +YYRV P+ W PE + KF SDVWSFGV L+E+ T+
Sbjct 669 IGDFGMSRDIY-STDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYG 727
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
Q++ E + +G L RP CP +VY +M+ CW+ E
Sbjct 728 KQ--------------PWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQ 773
Query 1159 RPTFENLIPILKTVHE 1174
R + +++ L+ + +
Sbjct 774 RLSMKDVHARLQALAQ 789
Score = 265 bits (677), Expect = 1e-73, Method: Composition-based stats.
Identities = 78/345 (23%), Positives = 129/345 (37%), Gaps = 52/345 (15%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
P E + +P+ S H + +++I LG+G V+
Sbjct 480 SPTEGKGSGLQGHIMENPQY--FSDTCVHHIKRQDIILKWELGEGAFGKVFLAEC----- 532
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
++D+D ++ V +K L + + F A L++ + H H+
Sbjct 533 ----YNLLNDQD----------KMLVAVKALKEASENARQDFQREAELLTMLQHQHIVRF 578
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRE--------------RGHVPMAWKMVVAQQLA 719
GVC G +MV EY+ HG L+ +LR G + + + VA Q+A
Sbjct 579 FGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVA 638
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE------RV 773
+ + YL + + VH ++ RN L+ G +K+ D G+ S + +
Sbjct 639 AGMVYLASLHFVHRDLATRNCLV-------GQGLVVKIGDFGMSRDIYSTDYYRVGGRTM 691
Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833
I W+ PE + ST D W FG L EI G+ P S +E + L
Sbjct 692 LPIRWMPPESIL--YRKFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGREL 749
Query 834 --PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
P P + + C EP QR S + + L L +
Sbjct 750 ERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQALAQAPPSY 794
>sp|Q90413|FGFR4_DANRE Fibroblast growth factor receptor 4 OS=Danio
rerio OX=7955 GN=fgfr4 PE=1 SV=1
Length=922
Score = 281 bits (719), Expect = 2e-78, Method: Composition-based stats.
Identities = 104/330 (32%), Positives = 158/330 (48%), Gaps = 42/330 (13%)
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE---MVA 928
+ + + P F + L + LGEG FG+V N + VA
Sbjct 553 CSPMLAGVMEFELPYDPDWEFPRENLTLGKPLGEGCFGQVVRAEAYGINKENQDHMATVA 612
Query 929 VKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
VK LK D + + E+++++ + H++II G C G L +++EY GSLR
Sbjct 613 VKMLKDDATDKDLADLISEMELMKVMDKHKNIINLLGVCTQDG--PLYVLVEYASKGSLR 670
Query 988 DYL-----------------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030
+YL P + L+ A Q+ GM YL ++ IHRDLAARNVL
Sbjct 671 EYLRARRPPGMDYTFDVTKVPEEQLTFKDLVSCAYQVARGMEYLASKRCIHRDLAARNVL 730
Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
+ D ++KI DFGLA+ V + +YY+ +G PV W APE L + + + SDVWSFGV
Sbjct 731 VTEDNVMKIADFGLARGVHQ-IDYYKKTTNGRMPVKWMAPEALFDRVYTHQSDVWSFGVL 789
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
++E+ T L G + V L +LL+ G R+ +P C E+Y M+
Sbjct 790 MWEIFT--------------LGGSPYPGIPVEELFKLLKEGHRMDKPSNCTHELYMKMRE 835
Query 1151 CWETEASFRPTFENLIPILK----TVHEKY 1176
CW + RPTF+ L+ L ++ ++Y
Sbjct 836 CWHAVPTQRPTFKQLVEELDRVLVSISDEY 865
Score = 232 bits (591), Expect = 1e-61, Method: Composition-based stats.
Identities = 66/315 (21%), Positives = 113/315 (36%), Gaps = 51/315 (16%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L ++ +T LG+G V + E + +
Sbjct 562 EFELPYDPDWEFPRENLTLGKPLGEGCFGQV-----------------VRAEAYGINKEN 604
Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVS-HTHLAFVHGVCVRGPENIMVTEYV 690
+ V +K+L D L LM + H ++ + GVC + ++ EY
Sbjct 605 QDHMATVAVKMLKDDATDKDLADLISEMELMKVMDKHKNIINLLGVCTQDGPLYVLVEYA 664
Query 691 EHGPLDVWLRRERG---------------HVPMAWKMVVAQQLASALSYLENKNLVHGNV 735
G L +LR R + + A Q+A + YL +K +H ++
Sbjct 665 SKGSLREYLRARRPPGMDYTFDVTKVPEEQLTFKDLVSCAYQVARGMEYLASKRCIHRDL 724
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGAN 789
RN+L+ + +K++D G+ G ++ R+P W+APE L
Sbjct 725 AARNVLVTEDNV-------MKIADFGLARGVHQIDYYKKTTNGRMPVKWMAPEALFDRV- 776
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847
+ D W FG + EI G +P E + HR+ P +L +
Sbjct 777 -YTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPSNCTHELYMKMRE 835
Query 848 CLTYEPTQRPSFRTI 862
C PTQRP+F+ +
Sbjct 836 CWHAVPTQRPTFKQL 850
>sp|O42127|FGFR3_XENLA Fibroblast growth factor receptor 3 OS=Xenopus
laevis OX=8355 GN=fgfr3 PE=2 SV=1
Length=802
Score = 278 bits (712), Expect = 2e-78, Method: Composition-based stats.
Identities = 100/291 (34%), Positives = 145/291 (50%), Gaps = 38/291 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGWKQEIDILRTL-YHEH 958
LGEG FG+V + + VAVK LK D + S E+++++ + H++
Sbjct 468 LGEGCFGQVVMAEAIGIDKERPNKPATVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 527
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQLL 1001
II G C G L +++EY GSLR+YL + L+
Sbjct 528 IINLLGACTQDG--PLYVLVEYASKGSLREYLKARRPPGMDYSFDACKIPAEQLTFKDLV 585
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
A Q+ GM YL +Q IHRDLAARNVL+ +D ++KI DFGLA+ + +YY+ +G
Sbjct 586 SCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDI-HNIDYYKKTTNG 644
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
PV W APE L + + + SDVWS+GV L+E+ T L G + V
Sbjct 645 RLPVKWMAPEALFDRIYTHHSDVWSYGVLLWEIFT--------------LGGSPYPGIPV 690
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
L +LL+ G R+ +P C E+Y +M+ CW S RP F+ L+ L V
Sbjct 691 EELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPAFKQLVEDLDRV 741
Score = 232 bits (591), Expect = 2e-62, Method: Composition-based stats.
Identities = 62/319 (19%), Positives = 114/319 (36%), Gaps = 51/319 (16%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
A+ L L + + +T LG+G V + E +
Sbjct 442 ANVSELGLPLDPKWELLRSRLTLGKPLGEGCFGQV-----------------VMAEAIGI 484
Query 629 PGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMV 686
+ V +K+L D L +M + H ++ + G C + ++
Sbjct 485 DKERPNKPATVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVL 544
Query 687 TEYVEHGPLDVWLRRERG---------------HVPMAWKMVVAQQLASALSYLENKNLV 731
EY G L +L+ R + + A Q+A + YL ++ +
Sbjct 545 VEYASKGSLREYLKARRPPGMDYSFDACKIPAEQLTFKDLVSCAYQVARGMEYLASQKCI 604
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLP 785
H ++ RN+L+ + +K++D G+ ++ R+P W+APE L
Sbjct 605 HRDLAARNVLVTDDNV-------MKIADFGLARDIHNIDYYKKTTNGRLPVKWMAPEALF 657
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLAT 843
+ D W +G L EI G +P E + HR+ P +L
Sbjct 658 DRI--YTHHSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYM 715
Query 844 LTSQCLTYEPTQRPSFRTI 862
+ +C P+QRP+F+ +
Sbjct 716 IMRECWHAVPSQRPAFKQL 734
>sp|P22455|FGFR4_HUMAN Fibroblast growth factor receptor 4 OS=Homo
sapiens OX=9606 GN=FGFR4 PE=1 SV=2
Length=802
Score = 278 bits (712), Expect = 3e-78, Method: Composition-based stats.
Identities = 103/304 (34%), Positives = 148/304 (49%), Gaps = 38/304 (13%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCY---DPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
F + L + LGEG FG+V DP VAVK LK + + +
Sbjct 460 WEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVS 519
Query 947 EIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-------------- 991
E+++++ + H++II G C +G L +++E G+LR++L
Sbjct 520 EMEVMKLIGRHKNIINLLGVCTQEG--PLYVIVECAAKGNLREFLRARRPPGPDLSPDGP 577
Query 992 ---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ V
Sbjct 578 RSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGV 637
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
+YY+ +G PV W APE L + + + SDVWSFG+ L+E+ T
Sbjct 638 HH-IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFT------------ 684
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
L G + V L LL G R+ RP CP E+Y LM+ CW S RPTF+ L+
Sbjct 685 --LGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEA 742
Query 1169 LKTV 1172
L V
Sbjct 743 LDKV 746
Score = 237 bits (604), Expect = 5e-64, Method: Composition-based stats.
Identities = 70/315 (22%), Positives = 119/315 (38%), Gaps = 51/315 (16%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
+L+L + + LG+G V +R E G + P R
Sbjct 451 SLDLPLDPLWEFPRDRLVLGKPLGEGCFGQV----VRAEAFG------------MDPARP 494
Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690
Q V +K+L + D L +M + H ++ + GVC + ++ E
Sbjct 495 -DQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECA 553
Query 691 EHGPLDVWLRRER---------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNV 735
G L +LR R G + + A Q+A + YLE++ +H ++
Sbjct 554 AKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDL 613
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGAN 789
RN+L+ + +K++D G+ G + + + W+APE L
Sbjct 614 AARNVLVTEDNV-------MKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRV- 665
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847
+ D W FG L EI G +P E + HR+ P P+L L +
Sbjct 666 -YTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRE 724
Query 848 CLTYEPTQRPSFRTI 862
C P+QRP+F+ +
Sbjct 725 CWHAAPSQRPTFKQL 739
>sp|Q06187|BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo sapiens
OX=9606 GN=BTK PE=1 SV=3
Length=659
Score = 275 bits (702), Expect = 3e-78, Method: Composition-based stats.
Identities = 87/426 (20%), Positives = 162/426 (38%), Gaps = 64/426 (15%)
Query 446 SIRDGIHGPLLEPFVQAKLRPE--DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLR 503
+ + + + L+ E +G +++ S S + ++V +S G +R
Sbjct 277 EMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKS---TGDPQGVIR 332
Query 504 KFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLII 563
+ + + F ++ EL Q + L+ +
Sbjct 333 HYVVCSTPQSQYYLAEKHLFSTIPELINYHQHN---SAGLISRLKYP------------V 377
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
+ + +P T L S+ +D K++T L LG G V G+ R
Sbjct 378 SQQNKNAPSTAGLGYGSW-EIDPKDLTFLKELGTGQFGVVKYGKWRG------------- 423
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
+ V +K++ F E A +M +SH L ++GVC +
Sbjct 424 ------------QYDVAIKMIKEGSMS-EDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPI 470
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
++TEY+ +G L +LR R + + + + A+ YLE+K +H ++ RN L+
Sbjct 471 FIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVN 530
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKW 798
G+ +K+SD G+ L E + W PE L + S+ D W
Sbjct 531 DQGV-------VKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLM--YSKFSSKSDIW 581
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
FG + EI G+ P + + SE + RL P + ++ T+ C + +R
Sbjct 582 AFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADER 641
Query 857 PSFRTI 862
P+F+ +
Sbjct 642 PTFKIL 647
Score = 256 bits (653), Expect = 1e-71, Method: Composition-based stats.
Identities = 90/289 (31%), Positives = 142/289 (49%), Gaps = 28/289 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ L +++LG G FG V + D VA+K +K G + +E
Sbjct 395 WEIDPKDLTFLKELGTGQFGVVKYGKWRGQYD-----VAIKMIKE--GSMSEDEFIEEAK 447
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQI 1007
++ L HE +++ G C Q + + ++ EY+ G L +YL RH QLL + +
Sbjct 448 VMMNLSHEKLVQLYGVCTKQ--RPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDV 505
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
CE M YL ++ ++HRDLAARN L+++ +VK+ DFGL++ V + Y PV W
Sbjct 506 CEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDE--YTSSVGSKFPVRW 563
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
PE L KF SD+W+FGV ++E+ + L + + T E
Sbjct 564 SPPEVLMYSKFSSKSDIWAFGVLMWEIYS--------------LGKMPYERFTNSETAEH 609
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP-ILKTVHEK 1175
+ +G RL RP +VY +M +CW +A RPTF+ L+ IL + E+
Sbjct 610 IAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 658
>sp|P00530|FPS_FUJSV Tyrosine-protein kinase transforming protein
Fps OS=Fujinami sarcoma virus OX=11885 GN=V-FPS PE=3 SV=1
Length=873
Score = 280 bits (715), Expect = 3e-78, Method: Composition-based stats.
Identities = 94/436 (22%), Positives = 168/436 (39%), Gaps = 80/436 (18%)
Query 448 RDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPI 507
+ HG + VQ +L G +L+ S +L+V DG R F I
Sbjct 509 QAWYHGAIPRSEVQ-ELLKYSGDFLVRESQGKQ-EYVLSV-----LWDGQP----RHFII 557
Query 508 EQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGA 567
+ D + LE G P++ L L +P + I++ A
Sbjct 558 QAADNLYRLEDDG--LPTIPLLIDHLLQS----------------QRPITRKSGIVLTRA 599
Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
+ ++ +++ +G+G V+ GRLR +
Sbjct 600 VLKDK---------WVLNHEDVLLGERIGRGNFGEVFSGRLRADN--------------- 635
Query 628 VPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
V +K + ++ F + A ++ Q +H ++ + GVC + +V
Sbjct 636 ---------TPVAVKSCRETLPPELKAKFLQEARILKQCNHPNIVRLIGVCTQKQPIYIV 686
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
E V+ G +LR + + M + + + A+ + YLE+K+ +H ++ RN L+
Sbjct 687 MELVQGGDFLSFLRSKGPRLKMKKLIKMMENAAAGMEYLESKHCIHRDLAARNCLVTEKN 746
Query 747 LAEGTSPFIKLSDPGVGL----GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGF 800
+K+SD G+ G + +++IP W APE L G S+ D W F
Sbjct 747 -------TLKISDFGMSRQEEDGVYASTGGMKQIPVKWTAPEALNYG--WYSSESDVWSF 797
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPS 858
G L E G P + S + ++ RL PE + L +C Y+P +RPS
Sbjct 798 GILLWEAFSLGAVPYANLSNQQTREAIEQGVRLEPPEQCPEDVYRLMQRCWEYDPHRRPS 857
Query 859 FRTILRDLTRLQPHNL 874
F + +DL ++ +
Sbjct 858 FGAVHQDLIAIRKRHR 873
Score = 273 bits (698), Expect = 7e-76, Method: Composition-based stats.
Identities = 85/290 (29%), Positives = 140/290 (48%), Gaps = 23/290 (8%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
V + + +G G+FG+V N VAVK+ + P+ ++ + QE
Sbjct 605 WVLNHEDVLLGERIGRGNFGEVFSGRLRADN----TPVAVKSCRETLPPELKAKFLQEAR 660
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQI 1007
IL+ H +I++ G C + + + +VME V G +L + + +L+ +
Sbjct 661 ILKQCNHPNIVRLIGVCTQK--QPIYIVMELVQGGDFLSFLRSKGPRLKMKKLIKMMENA 718
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
GM YL ++H IHRDLAARN L+ +KI DFG+++ +G Y PV W
Sbjct 719 AAGMEYLESKHCIHRDLAARNCLVTEKNTLKISDFGMSRQEEDGV-YASTGGMKQIPVKW 777
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE L + SDVWSFG+ L+E + L + ++ + E
Sbjct 778 TAPEALNYGWYSSESDVWSFGILLWEAFS--------------LGAVPYANLSNQQTREA 823
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
+E+G RL P++CP +VY LM+ CWE + RP+F + L + ++++
Sbjct 824 IEQGVRLEPPEQCPEDVYRLMQRCWEYDPHRRPSFGAVHQDLIAIRKRHR 873
>sp|P24786|NTRK3_PIG NT-3 growth factor receptor OS=Sus scrofa
OX=9823 GN=NTRK3 PE=2 SV=1
Length=825
Score = 278 bits (712), Expect = 4e-78, Method: Composition-based stats.
Identities = 114/332 (34%), Positives = 160/332 (48%), Gaps = 36/332 (11%)
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY-CYD 917
I + + N P + +R + R+LGEG FGKV L CY+
Sbjct 500 HSVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYN 559
Query 918 PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLV 977
+ +VAVKALK D R +++E ++L L HEHI+K+ G C D L +V
Sbjct 560 LSPTKVKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PLIMV 616
Query 978 MEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQHYI 1020
EY+ G L +L H +GL+Q+L A QIC GM YL +QH++
Sbjct 617 FEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQICSGMVYLASQHFV 676
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + KF
Sbjct 677 HRDLATRNCLVGANLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRKFTT 735
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWSFGV L+E+ T+ Q++ + E + +G L RP C
Sbjct 736 ESDVWSFGVILWEIFTYGKQ--------------PWFQLSNTEVIECITQGRVLERPRVC 781
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P EVY +M CW+ E R + + IL +
Sbjct 782 PKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813
Score = 258 bits (660), Expect = 3e-71, Method: Composition-based stats.
Identities = 69/309 (22%), Positives = 119/309 (39%), Gaps = 51/309 (17%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ +++I LG+G V+ ++ V +K
Sbjct 533 IKRRDIVLKRELGEGAFGKVFLAECYNLSPTKV-------------------KMLVAVKA 573
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702
L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR
Sbjct 574 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633
Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+G + ++ + +A Q+ S + YL +++ VH ++ RN L+
Sbjct 634 PDAMILVDGQPRQAKGELGLSQMLHIASQICSGMVYLASQHFVHRDLATRNCLV------ 687
Query 749 EGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
G + +K+ D G+ S + + I W+ PE + +T D W FG
Sbjct 688 -GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGV 744
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860
L EI G+ P S +E + L P ++ + C EP QR + +
Sbjct 745 ILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIK 804
Query 861 TILRDLTRL 869
I + L L
Sbjct 805 EIYKILHAL 813
>sp|P35739|NTRK1_RAT High affinity nerve growth factor receptor
OS=Rattus norvegicus OX=10116 GN=Ntrk1 PE=1 SV=1
Length=799
Score = 278 bits (710), Expect = 4e-78, Method: Composition-based stats.
Identities = 102/316 (32%), Positives = 156/316 (49%), Gaps = 35/316 (11%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKA 934
++ + ++ + +LGEG FGKV L CY+ ND +VAVKALK
Sbjct 492 HIMENPQYFSDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALK- 550
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993
+ R + +E ++L L H+HI+++ G C + G L +V EY+ G L +L H
Sbjct 551 ETSENARQDFHREAELLTMLQHQHIVRFFGVCTEGG--PLLMVFEYMRHGDLNRFLRSHG 608
Query 994 ---------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
+GL QLL A Q+ GM YL + H++HRDLA RN L+ +VK
Sbjct 609 PDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVK 668
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
IGDFG+++ + +YYRV P+ W PE + KF SDVWSFGV L+E+ T+
Sbjct 669 IGDFGMSRDIY-STDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYG 727
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
Q++ E + +G L RP CP +VY +M+ CW+ E
Sbjct 728 KQ--------------PWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQ 773
Query 1159 RPTFENLIPILKTVHE 1174
R + +++ L+ + +
Sbjct 774 RLSMKDVHARLQALAQ 789
Score = 265 bits (678), Expect = 9e-74, Method: Composition-based stats.
Identities = 78/345 (23%), Positives = 130/345 (38%), Gaps = 52/345 (15%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
P E + +P+ S H + +++I LG+G V+
Sbjct 480 SPTEGKGSGLQGHIMENPQY--FSDTCVHHIKRQDIILKWELGEGAFGKVFLAEC----- 532
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
++D+D ++ V +K L + + F+ A L++ + H H+
Sbjct 533 ----YNLLNDQD----------KMLVAVKALKETSENARQDFHREAELLTMLQHQHIVRF 578
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRE--------------RGHVPMAWKMVVAQQLA 719
GVC G +MV EY+ HG L+ +LR G + + + VA Q+A
Sbjct 579 FGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVA 638
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE------RV 773
+ + YL + + VH ++ RN L+ G +K+ D G+ S + +
Sbjct 639 AGMVYLASLHFVHRDLATRNCLV-------GQGLVVKIGDFGMSRDIYSTDYYRVGGRTM 691
Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833
I W+ PE + ST D W FG L EI G+ P S +E + L
Sbjct 692 LPIRWMPPESIL--YRKFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGREL 749
Query 834 --PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
P P + + C EP QR S + + L L +
Sbjct 750 ERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQALAQAPPSY 794
>sp|O22558|STY8_ARATH Serine/threonine-protein kinase STY8 OS=Arabidopsis
thaliana OX=3702 GN=STY8 PE=1 SV=2
Length=546
Score = 271 bits (692), Expect = 4e-78, Method: Composition-based stats.
Identities = 83/302 (27%), Positives = 143/302 (47%), Gaps = 29/302 (10%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CG 937
+ + +D LK + + G +G + Y + VA+K LK D
Sbjct 268 CIEIPTDGTDEWEIDVTQLKIEKKVASGSYGDLHRGTY------CSQEVAIKFLKPDRVN 321
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995
+ + QE+ I+R + H++++++ G C +L +V E++ GS+ D+L +
Sbjct 322 NEMLREFSQEVFIMRKVRHKNVVQFLGACTRS--PTLCIVTEFMARGSIYDFLHKQKCAF 379
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
L LL A + +GM+YLH + IHRDL N+L+D LVK+ DFG+A+ E
Sbjct 380 KLQTLLKVALDVAKGMSYLHQNNIIHRDLKTANLLMDEHGLVKVADFGVARVQIESG--- 436
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
V W APE ++ + + +DV+S+ + L+ELLT P FL + A
Sbjct 437 -VMTAETGTYRWMAPEVIEHKPYNHKADVFSYAIVLWELLTG-----DIPYAFLTPLQAA 490
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
G ++++G R P K +V L++ CW + RP FE +I +L+ + ++
Sbjct 491 VG---------VVQKGLRPKIPKKTHPKVKGLLERCWHQDPEQRPLFEEIIEMLQQIMKE 541
Query 1176 YQ 1177
Sbjct 542 VN 543
Score = 236 bits (602), Expect = 8e-66, Method: Composition-based stats.
Identities = 57/271 (21%), Positives = 114/271 (42%), Gaps = 18/271 (7%)
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQV 665
++ + E K+ R V +K L P ++++ F + +M +V
Sbjct 279 WEIDVTQLKIEKKVASGSYGDLHRGTYCSQEVAIKFLKPDRVNNEMLREFSQEVFIMRKV 338
Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL 725
H ++ G C R P +VTE++ G + +L +++ + + VA +A +SYL
Sbjct 339 RHKNVVQFLGACTRSPTLCIVTEFMARGSIYDFLHKQKCAFKLQTLLKVALDVAKGMSYL 398
Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR---EERVERIPWLAPE 782
N++H ++ N+L+ GL +K++D GV + W+APE
Sbjct 399 HQNNIIHRDLKTANLLMDEHGL-------VKVADFGVARVQIESGVMTAETGTYRWMAPE 451
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCP 839
+ + D + + L E+ G+ P +P + + ++P+ + P
Sbjct 452 VIEH--KPYNHKADVFSYAIVLWELL-TGDIPYAFLTPLQAAVGVVQKGLRPKIPKKTHP 508
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
++ L +C +P QRP F I+ L ++
Sbjct 509 KVKGLLERCWHQDPEQRPLFEEIIEMLQQIM 539
>sp|F4JTP5|STY46_ARATH Serine/threonine-protein kinase STY46 OS=Arabidopsis
thaliana OX=3702 GN=STY46 PE=1 SV=1
Length=575
Score = 272 bits (695), Expect = 4e-78, Method: Composition-based stats.
Identities = 78/297 (26%), Positives = 139/297 (47%), Gaps = 29/297 (10%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CG 937
V + +D + ++LK + G +G + Y + VA+K LK +
Sbjct 272 HVPIPNDGTDVWEINLKHLKFGHKIASGSYGDLYKGTY------CSQEVAIKVLKPERLD 325
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995
+ QE+ I+R + H++++++ G C L +V E++P GS+ DYL +
Sbjct 326 SDLEKEFAQEVFIMRKVRHKNVVQFIGACTKP--PHLCIVTEFMPGGSVYDYLHKQKGVF 383
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
L L A IC+GM+YLH + IHRDL A N+L+D + +VK+ DFG+A+
Sbjct 384 KLPTLFKVAIDICKGMSYLHQNNIIHRDLKAANLLMDENEVVKVADFGVARV----KAQT 439
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
V W APE ++ + + +DV+S+G+ L+ELLT +
Sbjct 440 GVMTAETGTYRWMAPEVIEHKPYDHKADVFSYGIVLWELLTGKLPYEY------------ 487
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ ++++G R P ++ L++ WE +++ RP F +I L+ +
Sbjct 488 --MTPLQAAVGVVQKGLRPTIPKNTHPKLAELLERLWEHDSTQRPDFSEIIEQLQEI 542
Score = 245 bits (626), Expect = 9e-69, Method: Composition-based stats.
Identities = 61/298 (20%), Positives = 118/298 (40%), Gaps = 44/298 (15%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
++ K + + G+ ++Y+G + V
Sbjct 281 DVWEINLKHLKFGHKIASGSYGDLYKGTYCSQ--------------------------EV 314
Query 640 VLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+KVL P D+ F + +M +V H ++ G C + P +VTE++ G +
Sbjct 315 AIKVLKPERLDSDLEKEFAQEVFIMRKVRHKNVVQFIGACTKPPHLCIVTEFMPGGSVYD 374
Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+L +++G + VA + +SYL N++H ++ N+L+ + +K+
Sbjct 375 YLHKQKGVFKLPTLFKVAIDICKGMSYLHQNNIIHRDLKAANLLMDE-------NEVVKV 427
Query 758 SDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
+D GV W+APE + D + +G L E+ G+ P
Sbjct 428 ADFGVARVKAQTGVMTAETGTYRWMAPEVIEH--KPYDHKADVFSYGIVLWELL-TGKLP 484
Query 815 LQSRSPSEKE-HFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ +P + Q+ R +P+ + P+LA L + ++ TQRP F I+ L +
Sbjct 485 YEYMTPLQAAVGVVQKGLRPTIPKNTHPKLAELLERLWEHDSTQRPDFSEIIEQLQEI 542
>sp|P35991|BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus musculus
OX=10090 GN=Btk PE=1 SV=4
Length=659
Score = 274 bits (700), Expect = 6e-78, Method: Composition-based stats.
Identities = 88/426 (21%), Positives = 162/426 (38%), Gaps = 64/426 (15%)
Query 446 SIRDGIHGPLLEPFVQAKLRPE--DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLR 503
+ + + + L+ E +G +++ S S + ++V +S G +R
Sbjct 277 EMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKS---TGEPQGVIR 332
Query 504 KFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLII 563
+ + + F ++ EL Q + L+ +
Sbjct 333 HYVVCSTPQSQYYLAEKHLFSTIPELINYHQHN---SAGLISRLKYP------------V 377
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
+ + +P T L S+ +D K++T L LG G V G+ R
Sbjct 378 SKQNKNAPSTAGLGYGSW-EIDPKDLTFLKELGTGQFGVVKYGKWRG------------- 423
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
+ V +K++ F E A +M +SH L ++GVC +
Sbjct 424 ------------QYDVAIKMIREGSMS-EDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPI 470
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
++TEY+ +G L +LR R + + + + A+ YLE+K +H ++ RN L+
Sbjct 471 FIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVN 530
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKW 798
G+ +K+SD G+ L E + W PE L + S+ D W
Sbjct 531 DQGV-------VKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLM--YSKFSSKSDIW 581
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
FG + EI G+ P + + SE + RL P + ++ T+ C + +R
Sbjct 582 AFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASERVYTIMYSCWHEKADER 641
Query 857 PSFRTI 862
PSF+ +
Sbjct 642 PSFKIL 647
Score = 254 bits (648), Expect = 5e-71, Method: Composition-based stats.
Identities = 88/289 (30%), Positives = 141/289 (49%), Gaps = 28/289 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ L +++LG G FG V + D VA+K ++ G + +E
Sbjct 395 WEIDPKDLTFLKELGTGQFGVVKYGKWRGQYD-----VAIKMIRE--GSMSEDEFIEEAK 447
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQI 1007
++ L HE +++ G C Q + + ++ EY+ G L +YL RH QLL + +
Sbjct 448 VMMNLSHEKLVQLYGVCTKQ--RPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDV 505
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
CE M YL ++ ++HRDLAARN L+++ +VK+ DFGL++ V + Y PV W
Sbjct 506 CEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDE--YTSSVGSKFPVRW 563
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
PE L KF SD+W+FGV ++E+ + L + + T E
Sbjct 564 SPPEVLMYSKFSSKSDIWAFGVLMWEIYS--------------LGKMPYERFTNSETAEH 609
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP-ILKTVHEK 1175
+ +G RL RP VY +M +CW +A RP+F+ L+ IL + E+
Sbjct 610 IAQGLRLYRPHLASERVYTIMYSCWHEKADERPSFKILLSNILDVMDEE 658
>sp|O48814|BIK1_ARATH Serine/threonine-protein kinase BIK1 OS=Arabidopsis
thaliana OX=3702 GN=BIK1 PE=1 SV=1
Length=395
Score = 265 bits (677), Expect = 7e-78, Method: Composition-based stats.
Identities = 84/288 (29%), Positives = 132/288 (46%), Gaps = 18/288 (6%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+GEG FG V D PT GTG ++AVK L + HR W EI+ L L H
Sbjct 73 IGEGGFGCVFKGWLDESTLTPTKPGTGLVIAVKKLNQEGFQGHRE-WLTEINYLGQLSHP 131
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMA 1012
+++K G C + + LV E++ GSL ++L R + + A +G+A
Sbjct 132 NLVKLIGYCLEDEHR--LLVYEFMQKGSLENHLFRRGAYFKPLPWFLRVNVALDAAKGLA 189
Query 1013 YLHAQ--HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
+LH+ I+RD+ A N+LLD D K+ DFGLA+ P G Y V + AP
Sbjct 190 FLHSDPVKVIYRDIKASNILLDADYNAKLSDFGLARDGPMGDLSY-VSTRVMGTYGYAAP 248
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTELL 1128
E + SDV+SFGV L E+L+ + + P K L+ A+ +T R + ++
Sbjct 249 EYMSSGHLNARSDVYSFGVLLLEILSGKRALDHNRPAKEENLVDWARPYLTSKRKVLLIV 308
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
+ + + + C E RPT + ++ L+ + +
Sbjct 309 DNRLDTQYLPEEAVRMASVAVQCLSFEPKSRPTMDQVVRALQQLQDNL 356
Score = 245 bits (625), Expect = 1e-70, Method: Composition-based stats.
Identities = 77/376 (20%), Positives = 139/376 (37%), Gaps = 54/376 (14%)
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
G S + + ++ + S +G+G V++G L D
Sbjct 42 TEGEILSSTPVKSFTFNELKLATRNFRPDSVIGEGGFGCVFKGWL--------------D 87
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
E L P + G L + +K L+ + + + Q+SH +L + G C+
Sbjct 88 ESTLTPTKP-GTGLVIAVKKLNQEGFQGHREWLTEINYLGQLSHPNLVKLIGYCLEDEHR 146
Query 684 IMVTEYVEHGPLDVWLRRER---GHVPMAWKMVVAQQLASALSYLENK--NLVHGNVCGR 738
++V E+++ G L+ L R +P ++ VA A L++L + +++ ++
Sbjct 147 LLVYEFMQKGSLENHLFRRGAYFKPLPWFLRVNVALDAAKGLAFLHSDPVKVIYRDIKAS 206
Query 739 NILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPECLPGGANSLS 792
NILL KLSD G+ + + + APE + G L+
Sbjct 207 NILLD-------ADYNAKLSDFGLARDGPMGDLSYVSTRVMGTYGYAAPEYMSSG--HLN 257
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ--------------HRLPEPSC 838
D + FG LLEI A +R E+ + +RL
Sbjct 258 ARSDVYSFGVLLLEILSGKRALDHNRPAKEENLVDWARPYLTSKRKVLLIVDNRLDTQYL 317
Query 839 P----QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894
P ++A++ QCL++EP RP+ ++R L +LQ + T
Sbjct 318 PEEAVRMASVAVQCLSFEPKSRPTMDQVVRALQQLQDNLGKPSQTNPVKDTKKLGFKTGT 377
Query 895 RYLKKIRDLGEGHFGK 910
+ R + FG+
Sbjct 378 TKSSEKRFTQK-PFGR 392
>sp|P54758|EPHA6_RAT Ephrin type-A receptor 6 OS=Rattus norvegicus
OX=10116 GN=Epha6 PE=2 SV=2
Length=1035
Score = 281 bits (720), Expect = 7e-78, Method: Composition-based stats.
Identities = 87/363 (24%), Positives = 152/363 (42%), Gaps = 57/363 (16%)
Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911
E +R + ++ + D + ++ R +G G FG+V
Sbjct 585 EEKRRTHLQNSHLRFPGIKTYIDPDTYEDPSLAVHEFEKEIDPSRIRIERVIGAGEFGEV 644
Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
T VA+K LK + R + +E I+ H +II+ +G +
Sbjct 645 CSGRLK-TPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSF 703
Query 972 ----------------------------------------KSLQLVMEYVPLGSLRDYLP 991
+ + +V+EY+ GSL +L
Sbjct 704 PAIGVEAFCPSFLRAGFLNGIQAPHPVTAGGSLPPRIPAGRPVMIVVEYMENGSLDSFLR 763
Query 992 RHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
+H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL++ +
Sbjct 764 KHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLE 823
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
+ E G P+ W APE + KF ASDVWS+G+ ++E++++ +
Sbjct 824 DDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDVWSYGIVMWEVMSYGER--------- 874
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+M+ + +E G RLP P CP ++ LM +CW+ E + RP F +++ L
Sbjct 875 -----PYWEMSNQDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFL 929
Query 1170 KTV 1172
+
Sbjct 930 DKL 932
Score = 263 bits (673), Expect = 9e-72, Method: Composition-based stats.
Identities = 87/404 (22%), Positives = 135/404 (33%), Gaps = 88/404 (22%)
Query 570 SPRTLNLSQLSFHR----VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
P T L+ H +D I +G G V GRL+ G
Sbjct 607 DPDTYEDPSLAVHEFEKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGK------------ 654
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVR----- 679
+E+ V +K L H D F AS+M Q H ++ + GV +
Sbjct 655 ---------REIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPA 705
Query 680 -------------------------------------GPENIMVTEYVEHGPLDVWLRRE 702
G ++V EY+E+G LD +LR+
Sbjct 706 IGVEAFCPSFLRAGFLNGIQAPHPVTAGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKH 765
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
GH + + + + +AS + YL + VH ++ RNIL+ ++ K+SD G+
Sbjct 766 DGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVN-------SNLVCKVSDFGL 818
Query 763 GL-------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
A + I W APE + S+A D W +G + E+ GE P
Sbjct 819 SRVLEDDPEAAYTTTGGKIPIRWTAPEAIA--YRKFSSASDVWSYGIVMWEVMSYGERPY 876
Query 816 QSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
S + + +RL P P L L C E RP F I+ L +L +
Sbjct 877 WEMSNQDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNP 936
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917
A V + Y + + + Y
Sbjct 937 SALHTLVEDILVMPESPGDVPEYPLFVTVGDW--LDSIKMGQYK 978
>sp|Q9LTC0|PBL19_ARATH Probable serine/threonine-protein kinase
PBL19 OS=Arabidopsis thaliana OX=3702 GN=PBL19 PE=1 SV=1
Length=410
Score = 265 bits (678), Expect = 1e-77, Method: Composition-based stats.
Identities = 82/286 (29%), Positives = 128/286 (45%), Gaps = 11/286 (4%)
Query 903 LGEGHFGKVSLYCYDPTNDGTG--EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+GEG FG V D + +VA+K L G Q W E+ L + H +++
Sbjct 92 IGEGGFGIVYKGKILSNGDSSDPPLVVAIKKLNR-QGLQGHKQWLAEVQFLGVVNHPNVV 150
Query 961 KYKGCCEDQGEKSL--QLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH 1015
K G C + GE + LV EY+ SL D+L H++ + L EG+ YLH
Sbjct 151 KLIGYCSEDGETGIERLLVYEYMSNRSLEDHLFPRRSHTLPWKKRLEIMLGAAEGLTYLH 210
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
I+RD + NVLLD+ K+ DFGLA+ P+G + V + APE ++
Sbjct 211 DLKVIYRDFKSSNVLLDDQFCPKLSDFGLAREGPDGDNTH-VTTARVGTHGYAAPEYVQT 269
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQ--SPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
SDV+SFGV LYE++T + + P + L + + R + +++ R
Sbjct 270 GHLRLKSDVYSFGVVLYEIITGRRTIERNKPVAERRLLDWVKEYPADSQRFSMIVDPRLR 329
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
P + L C + RPT E ++ LK + E+ +
Sbjct 330 NNYPAAGARSLAKLADLCLKKNDKERPTMEIVVERLKKIIEESDSE 375
Score = 225 bits (573), Expect = 2e-63, Method: Composition-based stats.
Identities = 75/410 (18%), Positives = 137/410 (33%), Gaps = 66/410 (16%)
Query 529 LGAALQGCLLRAGDDCFSLRRC-CLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587
L + R+ F+L+ LP P +L R NL S+ + +
Sbjct 30 LQNSAPELTNRSETSSFNLQTPRSLPSPRSIKDLYTEREQ-------NLRVFSYEELSKA 82
Query 588 EITQLSHL--GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
L G+G VY+G++ G L V +K L+
Sbjct 83 TYVFSRKLVIGEGGFGIVYKGKILSNGDSSDPP------------------LVVAIKKLN 124
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP----ENIMVTEYVEHGPLDVWLRR 701
+ + V+H ++ + G C E ++V EY+ + L+ L
Sbjct 125 RQGLQGHKQWLAEVQFLGVVNHPNVVKLIGYCSEDGETGIERLLVYEYMSNRSLEDHLFP 184
Query 702 ERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
R H +P ++ + A L+YL + +++ + N+LL KLSD
Sbjct 185 RRSHTLPWKKRLEIMLGAAEGLTYLHDLKVIYRDFKSSNVLLDDQFCP-------KLSDF 237
Query 761 GVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ + RV + APE + G L D + FG L EI
Sbjct 238 GLAREGPDGDNTHVTTARVGTHGYAAPEYVQTGHLRL--KSDVYSFGVVLYEIITGRRTI 295
Query 815 LQSRSPSE------KEHFYQRQHRLPEPSCPQ------------LATLTSQCLTYEPTQR 856
+++ +E + + R P+ LA L CL +R
Sbjct 296 ERNKPVAERRLLDWVKEYPADSQRFSMIVDPRLRNNYPAAGARSLAKLADLCLKKNDKER 355
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906
P+ ++ L ++ + ++ + + V ++ K + G
Sbjct 356 PTMEIVVERLKKIIEESDSEDYPMATTTTKESSQVRRRQVAKPEKQSLRG 405
>sp|Q07407|FGFR1_DROME Fibroblast growth factor receptor homolog
1 OS=Drosophila melanogaster OX=7227 GN=htl PE=1 SV=3
Length=729
Score = 275 bits (702), Expect = 1e-77, Method: Composition-based stats.
Identities = 100/347 (29%), Positives = 160/347 (46%), Gaps = 44/347 (13%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
T I + T + + + P + +L LGEG FG+V +
Sbjct 373 TMIMPVVRIQKQRTTVLQNGNEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVM 432
Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEK 972
+ +VAVK +K + +E+++++ + H +II GCC G
Sbjct 433 A------EVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNG-- 484
Query 973 SLQLVMEYVPLGSLRDYLPR---------------------HSIGLAQLLLFAQQICEGM 1011
L +++EY P G+L+D+L + H I L+ FA QI GM
Sbjct 485 PLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGM 544
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
YL ++ IHRDLAARNVL+ +D ++KI DFGLA+ + + +YYR +G P+ W APE
Sbjct 545 DYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDI-QSTDYYRKNTNGRLPIKWMAPE 603
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
L+E + SDVWS+G+ L+E++T+ M+ L L G
Sbjct 604 SLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTI-------------MSAEELYTYLMSG 650
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
+R+ +P KC +Y LM+ CW A RP F ++ + + + +
Sbjct 651 QRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTKED 697
Score = 231 bits (590), Expect = 9e-63, Method: Composition-based stats.
Identities = 63/354 (18%), Positives = 117/354 (33%), Gaps = 66/354 (19%)
Query 554 QPGETSNLIIMRGARASPR-TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
+ + ++ G +P S + + + + LG+G V
Sbjct 380 RIQKQRTTVLQNGNEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRV--------- 430
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQV-SHTHL 670
V +K++ H D +A +M + H ++
Sbjct 431 -----------------VMAEVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINI 473
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-------------------VPMAWK 711
+ G C + ++ EY HG L +L + R +
Sbjct 474 INLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDL 533
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----L 767
+ A Q+A + YL ++ +H ++ RN+L++ +K++D G+
Sbjct 534 IKFAHQIARGMDYLASRRCIHRDLAARNVLVS-------DDYVLKIADFGLARDIQSTDY 586
Query 768 SREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS-RSPSEKE 824
R+ R+P W+APE L + D W +G L EI G+ P + S E
Sbjct 587 YRKNTNGRLPIKWMAPESLQEKF--YDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELY 644
Query 825 HFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
+ R+ P + L QC + RP F I+ + +L
Sbjct 645 TYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTKEDY 698
>sp|Q5IS82|NTRK3_SAIBB NT-3 growth factor receptor OS=Saimiri
boliviensis boliviensis OX=39432 GN=NTRK3 PE=2 SV=1
Length=825
Score = 276 bits (707), Expect = 2e-77, Method: Composition-based stats.
Identities = 113/335 (34%), Positives = 159/335 (47%), Gaps = 36/335 (11%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914
P I + + N P + +R + R+LGEG FGKV L
Sbjct 497 GPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAE 556
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
CY+ + +VAVKALK D R +++E ++L L HEHI+K+ G C D L
Sbjct 557 CYNLSPTKDKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PL 613
Query 975 QLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQ 1017
+V EY+ G L +L H +GL+Q+L A QI GM YL +Q
Sbjct 614 IMVFEYMKHGDLNKFLRAHGPDAMILVDGQPXQAKGELGLSQMLHIASQIASGMVYLASQ 673
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
H++HRDLA RN + + LVKIGDFG+++ V +YYRV P+ W PE + K
Sbjct 674 HFVHRDLATRNCXVGANLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRK 732
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWSFGV L+E+ T+ Q++ + E + +G L RP
Sbjct 733 FTTESDVWSFGVILWEIFTYGKQ--------------PWFQLSNTEVIECITQGRVLERP 778
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
CP EVY +M CW+ E R + + IL +
Sbjct 779 RVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813
Score = 259 bits (661), Expect = 2e-71, Method: Composition-based stats.
Identities = 72/309 (23%), Positives = 125/309 (40%), Gaps = 51/309 (17%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ +++I LG+G V+ + + L P +D+ + V +K
Sbjct 533 IKRRDIVLKRELGEGAFGKVF----------------LAECYNLSPTKDK---MLVAVKA 573
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702
L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR
Sbjct 574 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633
Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+G + ++ + +A Q+AS + YL +++ VH ++ RN +
Sbjct 634 PDAMILVDGQPXQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCXV------ 687
Query 749 EGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
G + +K+ D G+ S + + I W+ PE + +T D W FG
Sbjct 688 -GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGV 744
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860
L EI G+ P S +E + L P ++ + C EP QR + +
Sbjct 745 ILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIK 804
Query 861 TILRDLTRL 869
I + L L
Sbjct 805 EIYKILHAL 813
>sp|Q2MHE4|HT1_ARATH Serine/threonine/tyrosine-protein kinase
HT1 OS=Arabidopsis thaliana OX=3702 GN=HT1 PE=1 SV=1
Length=390
Score = 264 bits (674), Expect = 2e-77, Method: Composition-based stats.
Identities = 85/335 (25%), Positives = 137/335 (41%), Gaps = 34/335 (10%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
+ + + +V T + L G ++
Sbjct 44 ETMEKKRFDSMESWSMILESENVETWEASKGEREEWTADLSQLFIGNKFASGAHSRIYRG 103
Query 915 CYDPTNDGTGEMVAVKAL-----KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
Y VAVK + K + + +K E+ +L L+H +I+++ C +
Sbjct 104 IYKQR------AVAVKMVRIPTHKEETRAKLEQQFKSEVALLSRLFHPNIVQFIAAC--K 155
Query 970 GEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
++ EY+ G+LR YL + +S+ + +L A I GM YLH+Q IHRDL +
Sbjct 156 KPPVYCIITEYMSQGNLRMYLNKKEPYSLSIETVLRLALDISRGMEYLHSQGVIHRDLKS 215
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
N+LL+++ VK+ DFG + + E + W APE +KE + DV+S
Sbjct 216 NNLLLNDEMRVKVADFGTSCLETQCREA----KGNMGTYRWMAPEMIKEKPYTRKVDVYS 271
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
FG+ L+EL T QG V + E+ ER P P C + H
Sbjct 272 FGIVLWELTTALLPF--------------QGMTPVQAAFAVAEKNERPPLPASCQPALAH 317
Query 1147 LMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
L+K CW S RP F N++ +L+ E + P
Sbjct 318 LIKRCWSENPSKRPDFSNIVAVLEKYDECVKEGLP 352
Score = 219 bits (559), Expect = 8e-62, Method: Composition-based stats.
Identities = 59/329 (18%), Positives = 118/329 (36%), Gaps = 37/329 (11%)
Query 550 CCLPQPGET---SNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606
C P +T + M R L V+ E ++
Sbjct 29 PCNPSSSKTNRYAEAETMEKKRFDSMESWSMILESENVETWEASKGE-----------RE 77
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD------PSHHDIALAFYETAS 660
+ S K R ++ V +K++ + + F +
Sbjct 78 EWTADLSQLFIGNKFASGAHSRIYRGIYKQRAVAVKMVRIPTHKEETRAKLEQQFKSEVA 137
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLA 719
L+S++ H ++ C + P ++TEY+ G L ++L ++ + + + +A ++
Sbjct 138 LLSRLFHPNIVQFIAACKKPPVYCIITEYMSQGNLRMYLNKKEPYSLSIETVLRLALDIS 197
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776
+ YL ++ ++H ++ N+LL +K++D G + +
Sbjct 198 RGMEYLHSQGVIHRDLKSNNLLLN-------DEMRVKVADFGTSCLETQCREAKGNMGTY 250
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF---YQRQHRL 833
W+APE + + +D + FG L E+ P Q +P + + L
Sbjct 251 RWMAPEMIKE--KPYTRKVDVYSFGIVLWEL-TTALLPFQGMTPVQAAFAVAEKNERPPL 307
Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
P P LA L +C + P++RP F I
Sbjct 308 PASCQPALAHLIKRCWSENPSKRPDFSNI 336
>sp|Q90330|FGFR4_COTCO Fibroblast growth factor receptor 4 OS=Coturnix
coturnix OX=9091 GN=FGFR4 PE=2 SV=1
Length=713
Score = 273 bits (699), Expect = 3e-77, Method: Composition-based stats.
Identities = 102/350 (29%), Positives = 156/350 (45%), Gaps = 38/350 (11%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
L Q + S +++R V D P F + L + L
Sbjct 326 LIRQFSLDSSSSGKSSTSLMRVTRLSSSCAPMLAGVVEMDLPLDSKWEFPREKLVLGKPL 385
Query 904 GEGHFGKVSLYCYDPTND---GTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHI 959
GEG FG+V + VAVK LK + + + E+++++ + H++I
Sbjct 386 GEGCFGQVVRAEAYGIDRQWPDRAVTVAVKMLKDNATDKDLADLISEMEMMKLMDKHKNI 445
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQLLL 1002
I G C G L +++E+ G+LR+YL + L+
Sbjct 446 INLLGVCTQDG--PLYVIVEFAAKGNLREYLRARRPPTPDYTFDITELHEEQLCFKDLVS 503
Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
Q+ GM YL ++ IHRDLAARNVL+ + ++KI DFGLA+ V +YY+ +G
Sbjct 504 CVYQVARGMEYLESRRCIHRDLAARNVLVTAENVMKIADFGLARDV-HDIDYYKKTSNGR 562
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
PV W APE L + + + SDVWSFG+ ++E+ T L G + V
Sbjct 563 LPVKWMAPEALFDRVYTHQSDVWSFGILMWEIFT--------------LGGSPYPGIPVE 608
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
L +LL+ G R+ P C E+Y LM+ CW RPTF+ L+ L +
Sbjct 609 ELFKLLKEGHRMDCPSNCTHELYMLMRECWHAVPLQRPTFKQLVEGLDKI 658
Score = 232 bits (592), Expect = 4e-63, Method: Composition-based stats.
Identities = 65/355 (18%), Positives = 126/355 (35%), Gaps = 51/355 (14%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
++L S ++++ LG+G V + E + +
Sbjct 363 EMDLPLDSKWEFPREKLVLGKPLGEGCFGQV-----------------VRAEAYGIDRQW 405
Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVS-HTHLAFVHGVCVRGPENIMVTEYV 690
+ + V +K+L + D L +M + H ++ + GVC + ++ E+
Sbjct 406 PDRAVTVAVKMLKDNATDKDLADLISEMEMMKLMDKHKNIINLLGVCTQDGPLYVIVEFA 465
Query 691 EHGPLDVWLRRERGHVP---------------MAWKMVVAQQLASALSYLENKNLVHGNV 735
G L +LR R P + Q+A + YLE++ +H ++
Sbjct 466 AKGNLREYLRARRPPTPDYTFDITELHEEQLCFKDLVSCVYQVARGMEYLESRRCIHRDL 525
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGAN 789
RN+L+ + +K++D G+ + + + W+APE L
Sbjct 526 AARNVLVTAENV-------MKIADFGLARDVHDIDYYKKTSNGRLPVKWMAPEALFDRV- 577
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847
+ D W FG + EI G +P E + HR+ P +L L +
Sbjct 578 -YTHQSDVWSFGILMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDCPSNCTHELYMLMRE 636
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902
C P QRP+F+ ++ L ++ + L ++ P+ D
Sbjct 637 CWHAVPLQRPTFKQLVEGLDKILAAISEEYLDLSMPFEQYSPSCEDTTSTCSSDD 691
>sp|Q91571|EPB1A_XENLA Ephrin type-B receptor 1-A OS=Xenopus laevis
OX=8355 GN=ephb1-a PE=1 SV=1
Length=985
Score = 279 bits (713), Expect = 4e-77, Method: Composition-based stats.
Identities = 77/308 (25%), Positives = 144/308 (47%), Gaps = 21/308 (7%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
++ + ++ ++K +G G FG+V + VA
Sbjct 592 MKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPSKRE-ISVA 650
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+K LKA + R + E I+ H +II+ +G + + ++ E++ G+L
Sbjct 651 IKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGALDS 708
Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
+L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++
Sbjct 709 FLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 768
Query 1047 AVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
+ + Y G PV W A E + KF ASDVWS+G+ ++E++++ +
Sbjct 769 YLQDDTSDPTYTSSLGGKIPVRWTAQEAIAYRKFTSASDVWSYGIVMWEVMSYGER---- 824
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
M+ + +E+ RLP P CP ++ LM +CW+ + + RP
Sbjct 825 ----------PYWTMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRLAE 874
Query 1165 LIPILKTV 1172
++ L+ +
Sbjct 875 IVNTLRPM 882
Score = 271 bits (694), Expect = 1e-74, Method: Composition-based stats.
Identities = 76/363 (21%), Positives = 138/363 (38%), Gaps = 46/363 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G VY+GRL++ +E+ V +
Sbjct 613 KEIDVSFVKIEEVIGAGEFGEVYKGRLKLPSK---------------------REISVAI 651
Query 642 KVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L F AS+M Q H ++ + GV + +++TE++E+G LD +LR
Sbjct 652 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 711
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD
Sbjct 712 QNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 764
Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ +IP W A E + ++A D W +G + E+ G
Sbjct 765 GLSRYLQDDTSDPTYTSSLGGKIPVRWTAQEAIA--YRKFTSASDVWSYGIVMWEVMSYG 822
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P + S + + ++ +RLP P CP L L C + RP I+ L +
Sbjct 823 ERPYWTMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRLAEIVNTLRPM 882
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG----E 925
+ + + S P + + + + Y +G +
Sbjct 883 IRNPASLKTVATIPAVPSQPLLDRSIPDISAFTSVDDWLSAIKMGQYRDNFLSSGFTSLQ 942
Query 926 MVA 928
+VA
Sbjct 943 LVA 945
>sp|P53356|HTK16_HYDVU Tyrosine-protein kinase HTK16 OS=Hydra
vulgaris OX=6087 GN=HTK16 PE=2 SV=1
Length=757
Score = 274 bits (700), Expect = 4e-77, Method: Composition-based stats.
Identities = 110/363 (30%), Positives = 168/363 (46%), Gaps = 22/363 (6%)
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
+ P+ P + + + PE + + + ++ + P + + T +
Sbjct 399 KLPVPPSRPIKNNNGLPQPLPYPEFTNESDSDIFTRLECEKEKPLPKLPRPVVNHTEVPN 458
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVK 930
+ + K + ++LG G FG V + + G E+ VA+K
Sbjct 459 SVNVGQKGDQTMKNNAQQNIILKESISFGKELGVGEFGSVIKGIW--LSPGGKEINVAMK 516
Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
L D Q + +E ++ L H I+ G C + LV E V +G+L DYL
Sbjct 517 TLHKDKMVQGEKEFLREALVMSQLNHPCIVSLLGVCLGP---PMILVQELVEMGALLDYL 573
Query 991 PRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ I L L+A QI GM YL + ++HRDLAARN+LL N + VKI DFGL++AV
Sbjct 574 MDYQPEIQEVDLKLWASQIAFGMMYLELKRFVHRDLAARNILLANKKQVKISDFGLSRAV 633
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
G +YY+ ++ G PV WYAPE + F SDVWS+G+TL+E+ T D
Sbjct 634 GTGSDYYQAKQGGRWPVRWYAPESINYGTFSTKSDVWSYGITLWEMFTFGD--------- 684
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
+ G+MT + LE RL +PD+CP Y +M +CW + + RPTF L
Sbjct 685 -----LPYGEMTGNEVVSFLEHCGRLEKPDECPIHTYSIMLSCWHIDPNKRPTFNELHST 739
Query 1169 LKT 1171
T
Sbjct 740 FST 742
Score = 252 bits (643), Expect = 2e-69, Method: Composition-based stats.
Identities = 82/352 (23%), Positives = 137/352 (39%), Gaps = 51/352 (14%)
Query 531 AALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQ---------LSF 581
+ D F+ C +P ++ P ++N+ Q
Sbjct 418 LPYPEFTNESDSDIFTRLECEKEKPLPKLPRPVVNHTEV-PNSVNVGQKGDQTMKNNAQQ 476
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ + ++ I+ LG G +V +G G G+E+ V +
Sbjct 477 NIILKESISFGKELGVGEFGSVIKGIWLSPG---------------------GKEINVAM 515
Query 642 KVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L F A +MSQ++H + + GVC+ GP I+V E VE G L +L
Sbjct 516 KTLHKDKMVQGEKEFLREALVMSQLNHPCIVSLLGVCL-GPPMILVQELVEMGALLDYLM 574
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ + + A Q+A + YLE K VH ++ RNILLA +K+SD
Sbjct 575 DYQPEIQEVDLKLWASQIAFGMMYLELKRFVHRDLAARNILLANK-------KQVKISDF 627
Query 761 GVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ + + + + W APE + G + ST D W +G TL E+ G+
Sbjct 628 GLSRAVGTGSDYYQAKQGGRWPVRWYAPESINYG--TFSTKSDVWSYGITLWEMFTFGDL 685
Query 814 PLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
P + +E F + RL P+ ++ C +P +RP+F +
Sbjct 686 PYGEMTGNEVVSFLEHCGRLEKPDECPIHTYSIMLSCWHIDPNKRPTFNELH 737
Score = 36.6 bits (83), Expect = 1.6, Method: Composition-based stats.
Identities = 16/88 (18%), Positives = 27/88 (31%), Gaps = 12/88 (14%)
Query 450 GIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFP 506
HG + L DG +LI + P +L++ RS ++ F
Sbjct 10 WYHGKITREVAVQVLLRKGGRDGFFLIRDCGNAPEDYVLSMMFRS---------QILHFQ 60
Query 507 IEQQDGAFVLEGWGRSFPSVRELGAALQ 534
I G F + L + +
Sbjct 61 INCLGDNKFSIDNGPIFQGLDMLISYYK 88
>sp|Q9I8X3|FGFR3_DANRE Fibroblast growth factor receptor 3 OS=Danio
rerio OX=7955 GN=fgfr3 PE=2 SV=1
Length=800
Score = 275 bits (703), Expect = 4e-77, Method: Composition-based stats.
Identities = 101/304 (33%), Positives = 149/304 (49%), Gaps = 38/304 (13%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHR 941
P+ F + L + LGEG FG+V + + VAVK LK D +
Sbjct 448 PSDPKWEFTRTKLTLGKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDL 507
Query 942 SGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---------- 990
S E+++++ + H++II G C G L +++EY G+LR+YL
Sbjct 508 SDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLYVLVEYASKGNLREYLRARRPPGMDY 565
Query 991 -------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
P ++ L+ A Q+ GM YL ++ IHRD AARNVL+ D ++KI DFG
Sbjct 566 SFDTCKIPNETLTFKDLVSCAYQVARGMEYLASKKCIHRDPAARNVLVTEDNVMKIADFG 625
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
LA+ V +YY+ +G PV W APE L + + + SDVWS+GV L+E+ T
Sbjct 626 LARDV-HNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFT------- 677
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163
L G + V L +LL+ G R+ +P C E+Y +M+ CW S RPTF
Sbjct 678 -------LGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFR 730
Query 1164 NLIP 1167
L+
Sbjct 731 QLVE 734
Score = 235 bits (599), Expect = 2e-63, Method: Composition-based stats.
Identities = 80/370 (22%), Positives = 133/370 (36%), Gaps = 62/370 (17%)
Query 545 FSLRRC--CLPQPGETSNLIIMRGARAS----PRTLNLSQLSFHRVDQKEITQLSH---- 594
F L+R SN ++R AR S P N+S+L + E T+
Sbjct 405 FPLKRQVSLESNSSMNSNTPLVRIARLSSSDGPMLPNVSELELPSDPKWEFTRTKLTLGK 464
Query 595 -LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LG+G V + E + + L V +K+L D L
Sbjct 465 PLGEGCFGQV-----------------VMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDL 507
Query 654 -AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH------ 705
+M + H ++ + G C + ++ EY G L +LR R
Sbjct 508 SDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSF 567
Query 706 ---------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+ + A Q+A + YL +K +H + RN+L+ + +K
Sbjct 568 DTCKIPNETLTFKDLVSCAYQVARGMEYLASKKCIHRDPAARNVLVTEDNV-------MK 620
Query 757 LSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
++D G+ ++ R+P W+APE L + D W +G L EI
Sbjct 621 IADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRV--YTHQSDVWSYGVLLWEIFTL 678
Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
G +P E + HR+ P +L + +C P+QRP+FR ++ D R
Sbjct 679 GGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDR 738
Query 869 LQPHNLADVL 878
+ D
Sbjct 739 VLSMTSTDEY 748
>sp|Q08881|ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=Homo sapiens
OX=9606 GN=ITK PE=1 SV=1
Length=620
Score = 270 bits (690), Expect = 5e-77, Method: Composition-based stats.
Identities = 84/430 (20%), Positives = 158/430 (37%), Gaps = 61/430 (14%)
Query 449 DGIHGPLLEPFVQAKLRP--EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFP 506
+ + + + L ++G +++ S + ++V ++ + ++
Sbjct 238 EWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTA-GTYTVSVFTKAVVSENNPCIKHYHIK 296
Query 507 IEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRG 566
+ F S+ L Q G LR + G
Sbjct 297 ETNDNPKRYYVAEKYVFDSIPLLINYHQHNG---GGLVTRLRYP------------VCFG 341
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+ +P T L + +D E+T + +G G V+ G +
Sbjct 342 RQKAPVTAGLRYGKWV-IDPSELTFVQEIGSGQFGLVHLGYWLNKD-------------- 386
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+V +K + F E A +M ++SH L ++GVC+ +V
Sbjct 387 -----------KVAIKTIREGAMS-EEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLV 434
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
E++EHG L +LR +RG + + + ++YLE ++H ++ RN L+
Sbjct 435 FEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLV---- 490
Query 747 LAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFG 801
G + IK+SD G+ L + + W +PE + S+ D W FG
Sbjct 491 ---GENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFS--FSRYSSKSDVWSFG 545
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859
+ E+ +G+ P ++RS SE RL P + + + + C P RP+F
Sbjct 546 VLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAF 605
Query 860 RTILRDLTRL 869
+LR L +
Sbjct 606 SRLLRQLAEI 615
Score = 254 bits (649), Expect = 2e-71, Method: Composition-based stats.
Identities = 84/307 (27%), Positives = 132/307 (43%), Gaps = 27/307 (9%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
P V L ++++G G FG V L + + VA+
Sbjct 336 YPVCFGRQKAPVTAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKDK-----VAI 390
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K ++ G + +E +++ L H +++ G C +Q + LV E++ G L DY
Sbjct 391 KTIRE--GAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQA--PICLVFEFMEHGCLSDY 446
Query 990 LP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
L R LL +CEGMAYL IHRDLAARN L+ ++++K+ DFG+ +
Sbjct 447 LRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRF 506
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
V + + Y PV W +PE ++ SDVWSFGV ++E+ +
Sbjct 507 VLD--DQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGK-------- 556
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
I + + E + G RL +P VY +M +CW+ RP F L+
Sbjct 557 ------IPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLR 610
Query 1168 ILKTVHE 1174
L + E
Sbjct 611 QLAEIAE 617
>sp|Q8GXZ3|PBL8_ARATH Probable serine/threonine-protein kinase
PBL8 OS=Arabidopsis thaliana OX=3702 GN=PBL8 PE=1 SV=1
Length=410
Score = 263 bits (672), Expect = 6e-77, Method: Composition-based stats.
Identities = 84/287 (29%), Positives = 134/287 (47%), Gaps = 15/287 (5%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGWKQEIDILRT 953
+ LGEG FG V Y N G VAVK L + HR W E++ L
Sbjct 69 FRPDYILGEGGFGTVYKG-YIDDNLRVGLKSLPVAVKVLNKEGLQGHRE-WLTEVNFLGQ 126
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEG 1010
L H +++K G C + + LV E++ GSL ++L R + ++ ++ A +G
Sbjct 127 LRHPNLVKLIGYCCEDDHR--LLVYEFMLRGSLENHLFRKTTAPLSWSRRMMIALGAAKG 184
Query 1011 MAYLHA--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+A+LH + I+RD N+LLD+D K+ DFGLAKA P+G E + V +
Sbjct 185 LAFLHNAERPVIYRDFKTSNILLDSDYTAKLSDFGLAKAGPQGDETH-VSTRVMGTYGYA 243
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTE 1126
APE + SDV+SFGV L E+LT S ++ P+K L+ A+ ++ R L +
Sbjct 244 APEYVMTGHLTARSDVYSFGVVLLEMLTGRKSVDKTRPSKEQNLVDWARPKLNDKRKLLQ 303
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+++ + + L C RP +++ L+ +
Sbjct 304 IIDPRLENQYSVRAAQKACSLAYYCLSQNPKARPLMSDVVETLEPLQ 350
Score = 236 bits (601), Expect = 3e-67, Method: Composition-based stats.
Identities = 73/386 (19%), Positives = 135/386 (35%), Gaps = 60/386 (16%)
Query 547 LRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606
L P+ + S R + + + + + K LG+G VY+G
Sbjct 33 LSDPSTPRFRDDS-----RTPISYAQVIPFTLFELETI-TKSFRPDYILGEGGFGTVYKG 86
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS 666
+ R + L V +KVL+ + + + Q+
Sbjct 87 YIDDNL------------------RVGLKSLPVAVKVLNKEGLQGHREWLTEVNFLGQLR 128
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYL 725
H +L + G C ++V E++ G L+ L R+ + + +M++A A L++L
Sbjct 129 HPNLVKLIGYCCEDDHRLLVYEFMLRGSLENHLFRKTTAPLSWSRRMMIALGAAKGLAFL 188
Query 726 EN--KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIP 777
N + +++ + NILL + KLSD G+ +E +
Sbjct 189 HNAERPVIYRDFKTSNILLD-------SDYTAKLSDFGLAKAGPQGDETHVSTRVMGTYG 241
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS 837
+ APE + G L+ D + FG LLE+ ++ ++R E+ + +L +
Sbjct 242 YAAPEYVMTG--HLTARSDVYSFGVVLLEMLTGRKSVDKTRPSKEQNLVDWARPKLNDKR 299
Query 838 ------CPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
P+L +L CL+ P RP ++ L LQ A +
Sbjct 300 KLLQIIDPRLENQYSVRAAQKACSLAYYCLSQNPKARPLMSDVVETLEPLQCTGDALIPC 359
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGE 905
+ A+ Y R
Sbjct 360 ATTTAGAAFAMGGVPDYRMHRRFAKN 385
>sp|Q5PP29|PBL4_ARATH Probable serine/threonine-protein kinase
PBL4 OS=Arabidopsis thaliana OX=3702 GN=PBL4 PE=2 SV=1
Length=412
Score = 263 bits (672), Expect = 6e-77, Method: Composition-based stats.
Identities = 86/286 (30%), Positives = 128/286 (45%), Gaps = 13/286 (5%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+GEG FG V D P+ G+G +VAVK LK + HR W E+D L L+H
Sbjct 89 IGEGGFGYVYKGWIDERTLSPSKPGSGMVVAVKKLKEEGFQGHRQ-WLAEVDCLGRLHHM 147
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYL 1014
+++K G C L LV EY+P GSL ++L R I + A G+A+L
Sbjct 148 NLVKLIGYCSKGDHIRL-LVYEYMPKGSLENHLFRRGAEPIPWRTRIKVAIGAARGLAFL 206
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H I+RD A N+LLD++ K+ DFGLAK P G + V + APE +
Sbjct 207 HEAQVIYRDFKASNILLDSEFNAKLSDFGLAKVGPTGDRTH-VSTQVMGTQGYAAPEYVA 265
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQM-TVLRLTELLERGE 1132
+ SDV+SFGV L ELL+ + L+ A + ++ +++
Sbjct 266 TGRITAKSDVYSFGVVLLELLSGRLTVDKTKVGVERNLVDWAIPYLGDKRKVFRIMDTKL 325
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P K C + C E RP +++ L+ + +
Sbjct 326 GGQYPHKGACLTANTALQCLNQEPKLRPKMSDVLSTLEELEMTLKS 371
Score = 233 bits (594), Expect = 3e-66, Method: Composition-based stats.
Identities = 67/333 (20%), Positives = 116/333 (35%), Gaps = 50/333 (15%)
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
G + TL + + + S +G+G VY+G + DE
Sbjct 59 EGELLASPTLKAFTFNELKTATRNFRPDSVIGEGGFGYVYKGWI--------------DE 104
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE-N 683
L P + G + V +K L + + ++ H +L + G C +G
Sbjct 105 RTLSPSKP-GSGMVVAVKKLKEEGFQGHRQWLAEVDCLGRLHHMNLVKLIGYCSKGDHIR 163
Query 684 IMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
++V EY+ G L+ L R +P ++ VA A L++L +++ + NILL
Sbjct 164 LLVYEYMPKGSLENHLFRRGAEPIPWRTRIKVAIGAARGLAFLHEAQVIYRDFKASNILL 223
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMD 796
+ KLSD G+ + + + + APE + G ++ D
Sbjct 224 D-------SEFNAKLSDFGLAKVGPTGDRTHVSTQVMGTQGYAAPEYVATG--RITAKSD 274
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR------------------QHRLPEPSC 838
+ FG LLE+ +++ E+ + P
Sbjct 275 VYSFGVVLLELLSGRLTVDKTKVGVERNLVDWAIPYLGDKRKVFRIMDTKLGGQYPHKGA 334
Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
A QCL EP RP +L L L+
Sbjct 335 CLTANTALQCLNQEPKLRPKMSDVLSTLEELEM 367
>sp|Q9LFP7|PBL34_ARATH Serine/threonine-protein kinase PBL34 OS=Arabidopsis
thaliana OX=3702 GN=PBL34 PE=1 SV=1
Length=493
Score = 266 bits (679), Expect = 8e-77, Method: Composition-based stats.
Identities = 88/282 (31%), Positives = 130/282 (46%), Gaps = 16/282 (6%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LGEG FG V + P GTG VAVK L D G Q W EI+ L L H
Sbjct 148 LGEGGFGCVFKGWIEENGTAPVKPGTGLTVAVKTLNPD-GLQGHKEWLAEINFLGNLLHP 206
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLLFAQQICEGMAYLH 1015
+++K G C + ++ LV E++P GSL ++L R S+ + + A +G+++LH
Sbjct 207 NLVKLVGYCIEDDQR--LLVYEFMPRGSLENHLFRRSLPLPWSIRMKIALGAAKGLSFLH 264
Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+ I+RD N+LLD D K+ DFGLAK P+ + + V + APE
Sbjct 265 EEALKPVIYRDFKTSNILLDADYNAKLSDFGLAKDAPDEGKTH-VSTRVMGTYGYAAPEY 323
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQ-MTVLRLTELLER 1130
+ SDV+SFGV L E+LT S ++ P L+ A+ + R LL+
Sbjct 324 VMTGHLTSKSDVYSFGVVLLEMLTGRRSMDKNRPNGEHNLVEWARPHLLDKRRFYRLLDP 383
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
K +V L C + RP +++ LK +
Sbjct 384 RLEGHFSIKGAQKVTQLAAQCLSRDPKIRPKMSDVVEALKPL 425
Score = 256 bits (655), Expect = 1e-73, Method: Composition-based stats.
Identities = 66/356 (19%), Positives = 126/356 (35%), Gaps = 51/356 (14%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
+S+ ++ L + ++ + S LG+G V++G + G+ +
Sbjct 111 SSSTPVISEELNISSHLRKFTFNDLKLSTRNFRPESLLGEGGFGCVFKGWIEENGTAPVK 170
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
G L V +K L+P + + + + H +L + G C
Sbjct 171 P---------------GTGLTVAVKTLNPDGLQGHKEWLAEINFLGNLLHPNLVKLVGYC 215
Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGN 734
+ + ++V E++ G L+ L R +P + +M +A A LS+L K +++ +
Sbjct 216 IEDDQRLLVYEFMPRGSLENHLFRRSLPLPWSIRMKIALGAAKGLSFLHEEALKPVIYRD 275
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGA 788
NILL KLSD G+ A + + APE + G
Sbjct 276 FKTSNILLD-------ADYNAKLSDFGLAKDAPDEGKTHVSTRVMGTYGYAAPEYVMTG- 327
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS----------- 837
L++ D + FG LLE+ + ++R E + L +
Sbjct 328 -HLTSKSDVYSFGVVLLEMLTGRRSMDKNRPNGEHNLVEWARPHLLDKRRFYRLLDPRLE 386
Query 838 -------CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
++ L +QCL+ +P RP ++ L L + +
Sbjct 387 GHFSIKGAQKVTQLAAQCLSRDPKIRPKMSDVVEALKPLPHLKDMASSSYYFQTMQ 442
>sp|P41242|MATK_MOUSE Megakaryocyte-associated tyrosine-protein
kinase OS=Mus musculus OX=10090 GN=Matk PE=1 SV=2
Length=505
Score = 266 bits (679), Expect = 8e-77, Method: Composition-based stats.
Identities = 105/354 (30%), Positives = 160/354 (45%), Gaps = 44/354 (12%)
Query 821 SEKEHFY--QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ H+ R L L + T+L
Sbjct 162 RDVIHYRVLHRDGHLTIDEAVCFCNLMDM-------VEHYTKDKGAICTKLVKPRRKQGA 214
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
+ A + ++L +GEG FG V Y G+ VAVK +K D
Sbjct 215 KSAEEELAKAGWLLDLQHLTLGAQIGEGEFGAVLQGEYL------GQKVAVKNIKCDVTA 268
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---I 995
Q + E ++ L H ++++ G G L +VME+V G+L ++L +
Sbjct 269 Q---AFLDETAVMTKLQHRNLVRLLGVILHHG---LYIVMEHVSKGNLVNFLRTRGRALV 322
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+QLL FA + EGM YL ++ +HRDLAARN+L+ D + K+ DFGLAKA +G +
Sbjct 323 STSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSS 382
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
R+ PV W APE LK +F SDVWSFGV L+E+ ++ +
Sbjct 383 RL------PVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRA--------------P 422
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+M++ ++E +E+G R+ PD CP V+ LM +CWE E + RP F ++ L
Sbjct 423 YPKMSLKEVSEAVEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRKIVEKL 476
Score = 262 bits (670), Expect = 2e-75, Method: Composition-based stats.
Identities = 98/422 (23%), Positives = 166/422 (39%), Gaps = 70/422 (17%)
Query 446 SIRDGIHGPLLEPFVQAKLRP-EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
S+ HG + +L+P EDGL+L+ S HP +L V+
Sbjct 116 SLMPWFHGKISGQEAIQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVI---------H 166
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ + +DG ++ F ++ ++ G C L + Q +++ +
Sbjct 167 YRVLHRDGHLTID-EAVCFCNLMDMVEHYTKDK---GAICTKLVKPRRKQGAKSAEEELA 222
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
+ +D + +T + +G+G V +G +
Sbjct 223 KAG--------------WLLDLQHLTLGAQIGEGEFGAVLQGEYLGQ------------- 255
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+V +K + A AF + ++M+++ H +L + GV +
Sbjct 256 -------------KVAVKNIKCDVT--AQAFLDETAVMTKLQHRNLVRLLGVILHHG-LY 299
Query 685 MVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+V E+V G L +LR R R V + + A +A + YLE+K LVH ++ RNIL++
Sbjct 300 IVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVS 359
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSR-EERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+A K+SD G+ + + W APE L G S+ D W FG
Sbjct 360 EDLVA-------KVSDFGLAKAERKGLDSSRLPVKWTAPEALKNG--RFSSKSDVWSFGV 410
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFR 860
L E+ G AP S E ++ +R+ P CP + TL C EP +RP FR
Sbjct 411 LLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFR 470
Query 861 TI 862
I
Sbjct 471 KI 472
>sp|O73878|EPB4B_DANRE Ephrin type-B receptor 4b OS=Danio rerio
OX=7955 GN=ephb4b PE=1 SV=2
Length=976
Score = 277 bits (709), Expect = 9e-77, Method: Composition-based stats.
Identities = 82/327 (25%), Positives = 139/327 (43%), Gaps = 21/327 (6%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
T P ++ + ++ ++K +G G FG
Sbjct 566 TRRRDPDPDKSGQFLMGQGIKVYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFG 625
Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
+V VA+K LK + R + E I+ H +II +G
Sbjct 626 EVCRGRLKVPGKKEN-YVAIKTLKGGYTDKQRRDFLSEASIMGQFQHPNIIHLEGVIT-- 682
Query 970 GEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027
+ ++ EY+ G+L +L QL+ + I GM YL ++HRDLAAR
Sbjct 683 ASCPVMILTEYMENGALDSFLRLNDGQFTPIQLVGMLRGIASGMKYLSEMSFVHRDLAAR 742
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
N+L++++ + K+ DFGL++ + E Y G P+ W APE + KF ASDVW
Sbjct 743 NILVNSNLVCKVSDFGLSRFLTENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDVW 802
Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
S+G+ ++E+++ + M+ + +E+ RLP P +CP ++
Sbjct 803 SYGIVMWEVMSFGER--------------PYWDMSNQDVINAIEQDYRLPPPPECPASLH 848
Query 1146 HLMKNCWETEASFRPTFENLIPILKTV 1172
LM +CW+ E S RP F ++ L +
Sbjct 849 QLMLDCWQKERSSRPRFCAIVSALDRL 875
Score = 263 bits (671), Expect = 1e-71, Method: Composition-based stats.
Identities = 78/304 (26%), Positives = 123/304 (40%), Gaps = 42/304 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G V GRL+V G +E V +
Sbjct 606 KEIDVSFVKIEEVIGAGEFGEVCRGRLKVPGK---------------------KENYVAI 644
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + D F AS+M Q H ++ + GV +++TEY+E+G LD +LR
Sbjct 645 KTLKGGYTDKQRRDFLSEASIMGQFQHPNIIHLEGVITASCPVMILTEYMENGALDSFLR 704
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G + + + +AS + YL + VH ++ RNIL+ ++ K+SD
Sbjct 705 LNDGQFTPIQLVGMLRGIASGMKYLSEMSFVHRDLAARNILVN-------SNLVCKVSDF 757
Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ +IP W APE + ++A D W +G + E+ G
Sbjct 758 GLSRFLTENSSDPTYTSSLGGKIPIRWTAPEAIA--FRKFTSASDVWSYGIVMWEVMSFG 815
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P S + + ++ +RLP P CP L L C E + RP F I+ L RL
Sbjct 816 ERPYWDMSNQDVINAIEQDYRLPPPPECPASLHQLMLDCWQKERSSRPRFCAIVSALDRL 875
Query 870 QPHN 873
+
Sbjct 876 IRNP 879
>sp|P54761|EPHB4_MOUSE Ephrin type-B receptor 4 OS=Mus musculus
OX=10090 GN=Ephb4 PE=1 SV=2
Length=987
Score = 278 bits (710), Expect = 9e-77, Method: Composition-based stats.
Identities = 82/333 (25%), Positives = 140/333 (42%), Gaps = 25/333 (8%)
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE-- 905
CL + R + + + + P F K + E
Sbjct 562 CLRKQSNGREVEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVI 621
Query 906 --GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963
G FG+V VA+K LK + R + E I+ H +II+ +
Sbjct 622 GAGEFGEVCRGRLKAPGKKES-CVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLE 680
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G + ++ E++ G+L +L + QL+ + I GM YL Y+H
Sbjct 681 GVVT--NSVPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVH 738
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFY 1079
RDLAARN+L++++ + K+ DFGL++ + E Y G P+ W APE + KF
Sbjct 739 RDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFT 798
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
ASD WS+G+ ++E+++ + M+ + +E+ RLP P
Sbjct 799 SASDAWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIEQDYRLPPPPD 844
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
CP ++ LM +CW+ + + RP F ++ L +
Sbjct 845 CPTSLHQLMLDCWQKDRNARPRFPQVVSALDKM 877
Score = 261 bits (668), Expect = 2e-71, Method: Composition-based stats.
Identities = 77/362 (21%), Positives = 136/362 (38%), Gaps = 60/362 (17%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G V GRL+ G +E V +
Sbjct 608 KEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGK---------------------KESCVAI 646
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV +++TE++E+G LD +LR
Sbjct 647 KTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSVPVMILTEFMENGALDSFLR 706
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G + + + + +AS + YL + VH ++ RNIL+ ++ K+SD
Sbjct 707 LNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVN-------SNLVCKVSDF 759
Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ +IP W APE + ++A D W +G + E+ G
Sbjct 760 GLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIA--FRKFTSASDAWSYGIVMWEVMSFG 817
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P S + + ++ +RLP P L L C + RP F ++ L ++
Sbjct 818 ERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKM 877
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+ + + + AS P + ++ FG V + A+
Sbjct 878 IRNPASLKIVARENGGASHPLLDQRQPHYS-------AFGSVGEWLR-----------AI 919
Query 930 KA 931
K
Sbjct 920 KM 921
>sp|Q63604|NTRK2_RAT BDNF/NT-3 growth factors receptor OS=Rattus
norvegicus OX=10116 GN=Ntrk2 PE=1 SV=1
Length=821
Score = 274 bits (701), Expect = 9e-77, Method: Composition-based stats.
Identities = 110/334 (33%), Positives = 160/334 (48%), Gaps = 33/334 (10%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914
P I + + +T + P + + + R+LGEG FGKV L
Sbjct 496 GPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAE 555
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
CY+ + +VAVK LK D R + +E ++L L HEHI+K+ G C + L
Sbjct 556 CYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGD--PL 612
Query 975 QLVMEYVPLGSLRDYLPRHS--------------IGLAQLLLFAQQICEGMAYLHAQHYI 1020
+V EY+ G L +L H + +Q+L AQQI GM YL +QH++
Sbjct 613 IMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFV 672
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + KF
Sbjct 673 HRDLATRNCLVGENLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRKFTT 731
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS GV L+E+ T+ Q++ + E + +G L RP C
Sbjct 732 ESDVWSLGVVLWEIFTYGKQ--------------PWYQLSNNEVIECITQGRVLQRPRTC 777
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
P EVY LM CW+ E R +N+ +L+ + +
Sbjct 778 PQEVYELMLGCWQREPHTRKNIKNIHTLLQNLAK 811
Score = 266 bits (679), Expect = 8e-74, Method: Composition-based stats.
Identities = 72/306 (24%), Positives = 123/306 (40%), Gaps = 48/306 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ + I LG+G V+ + + L P +D+ + V +K
Sbjct 532 IKRHNIVLKRELGEGAFGKVF----------------LAECYNLCPEQDK---ILVAVKT 572
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--- 700
L + + F+ A L++ + H H+ +GVCV G IMV EY++HG L+ +LR
Sbjct 573 LKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 632
Query 701 ---------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
+ + + +AQQ+A+ + YL +++ VH ++ RN L+ G
Sbjct 633 PDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV-------GE 685
Query 752 SPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ +K+ D G+ S + + I W+ PE + +T D W G L
Sbjct 686 NLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSLGVVLW 743
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
EI G+ P S +E + L P ++ L C EP R + + I
Sbjct 744 EIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHTRKNIKNIH 803
Query 864 RDLTRL 869
L L
Sbjct 804 TLLQNL 809
>sp|P54753|EPHB3_HUMAN Ephrin type-B receptor 3 OS=Homo sapiens
OX=9606 GN=EPHB3 PE=1 SV=2
Length=998
Score = 278 bits (710), Expect = 9e-77, Method: Composition-based stats.
Identities = 80/333 (24%), Positives = 146/333 (44%), Gaps = 26/333 (8%)
Query 848 CLTYE---PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
CL + + + ++ + ++ +K +G
Sbjct 581 CLRKQRHGSDSEYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIG 640
Query 905 EGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963
G FG+V G E+ VA+K LK + R + E I+ H +II+ +
Sbjct 641 AGEFGEVCRGRLK--QPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLE 698
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
G + + ++ E++ +L +L + QL+ + I GM YL +Y+H
Sbjct 699 GVVTKS--RPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVH 756
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFY 1079
RDLAARN+L++++ + K+ DFGL++ + + Y G P+ W APE + KF
Sbjct 757 RDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFT 816
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
ASDVWS+G+ ++E++++ + M+ + +E+ RLP P
Sbjct 817 SASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVINAVEQDYRLPPPMD 862
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
CP ++ LM +CW + + RP F ++ L +
Sbjct 863 CPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKL 895
Score = 261 bits (667), Expect = 4e-71, Method: Composition-based stats.
Identities = 76/348 (22%), Positives = 133/348 (38%), Gaps = 42/348 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G V GRL+ G +E+ V +
Sbjct 626 KEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGR---------------------REVFVAI 664
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + +++TE++E+ LD +LR
Sbjct 665 KTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLR 724
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD
Sbjct 725 LNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 777
Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ +IP W APE + ++A D W +G + E+ G
Sbjct 778 GLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYG 835
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P S + + ++ +RLP P CP L L C + RP F I+ L +L
Sbjct 836 ERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKL 895
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917
+ + + + S S P + + + Y
Sbjct 896 IRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYK 943
>sp|P00529|ROS_AVISU Tyrosine-protein kinase transforming protein
ros OS=UR2 avian sarcoma virus OX=354090 GN=V-ROS PE=3 SV=1
Length=402
Score = 262 bits (669), Expect = 1e-76, Method: Composition-based stats.
Identities = 99/287 (34%), Positives = 137/287 (48%), Gaps = 33/287 (11%)
Query 903 LGEGHFGKVSLYC-YDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG G FG+V D DG+GE VAVK LK Q +S + +E ++ H HI+
Sbjct 104 LGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMSKFDHPHIL 163
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--------LLLFAQQICEGMA 1012
K G C + L++E + G L YL Q LL IC+G
Sbjct 164 KLLGVCLLNEPQ--YLILELMEGGDLLSYLRGARKQKFQSPLLTLTDLLDICLDICKGCV 221
Query 1013 YLHAQHYIHRDLAARNVLLDND------RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
YL +IHRDLAARN L+ R+VKIGDFGLA+ + + ++YYR R +G PV
Sbjct 222 YLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYK-NDYYRKRGEGLLPVR 280
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE L + F SDVW+FGV ++E LT L ++ + +
Sbjct 281 WMAPESLIDGVFTNHSDVWAFGVLVWETLT--------------LGQQPYPGLSNIEVLH 326
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ G RL P+ CP ++ LM CW + RPTF + L+ +
Sbjct 327 HVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEIR 373
Score = 256 bits (653), Expect = 2e-74, Method: Composition-based stats.
Identities = 73/315 (23%), Positives = 114/315 (36%), Gaps = 36/315 (11%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
S + ++ LG G VYEG L D E RV
Sbjct 89 SLPAFPRDKLNLHKLLGSGAFGEVYEG------------------TALDILADGSGESRV 130
Query 640 VLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+K L D F + A LMS+ H H+ + GVC+ ++ E +E G L +
Sbjct 131 AVKTLKRGATDQEKSEFLKEAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSY 190
Query 699 LRRERGH------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752
LR R + + + + + YLE +H ++ RN L++ S
Sbjct 191 LRGARKQKFQSPLLTLTDLLDICLDICKGCVYLEKMRFIHRDLAARNCLVSEKQYGSC-S 249
Query 753 PFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+K+ D G+ + +R + W+APE L G + D W FG + E
Sbjct 250 RVVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLIDGV--FTNHSDVWAFGVLVWE 307
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
G+ P S E H + RL P + L ++C +P RP+F I
Sbjct 308 TLTLGQQPYPGLSNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQH 367
Query 865 DLTRLQPHNLADVLT 879
L ++ L
Sbjct 368 KLQEIRHSPLCFSYF 382
>sp|Q65XV8|RK176_ORYSJ Receptor-like cytoplasmic kinase 176 OS=Oryza
sativa subsp. japonica OX=39947 GN=RLCK176 PE=1 SV=1
Length=395
Score = 261 bits (668), Expect = 1e-76, Method: Composition-based stats.
Identities = 89/292 (30%), Positives = 137/292 (47%), Gaps = 18/292 (6%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LGEG FG V D PT GTG ++AVK L + HR W E++ L L H
Sbjct 76 LGEGGFGSVFKGWIDEKTLAPTKPGTGMVIAVKKLNQEGHQGHRE-WLAEVNYLGQLSHP 134
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMA 1012
++++ G C + ++ LV E++P GSL ++L R S + + A +G+A
Sbjct 135 YLVRLVGYCVEDEQR--LLVYEFMPRGSLENHLFRRSTHFQPLSWNLRMKIALGAAKGLA 192
Query 1013 YLHAQHY--IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
+LH+ I+RD NVLLD + K+ DFGLAK P G + + V + AP
Sbjct 193 FLHSDKVKVIYRDFKTSNVLLDANYDAKLSDFGLAKDGPTGDKSH-VSTRVMGTYGYAAP 251
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQG-QMTVLRLTELL 1128
E L SDV+SFGV L E+L+ + ++ PT L+ A+ M+ R+ +L
Sbjct 252 EYLATGHLTTKSDVYSFGVVLLEMLSGRRALDKNRPTGEHNLVEWARPYLMSKRRIFRIL 311
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180
+ + L C EA RP E ++ +L+ + + + A
Sbjct 312 DARLGGQYSLAKAQKAATLALQCISVEAKNRPNMEQVVAVLEQLQDSKETGA 363
Score = 239 bits (609), Expect = 2e-68, Method: Composition-based stats.
Identities = 76/348 (22%), Positives = 138/348 (40%), Gaps = 60/348 (17%)
Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
P P ++ A+ + ++L R + S LG+G +V++G +
Sbjct 40 PPTPRSEDEILEA----ANVKAFAFNEL---RTATRNFRPDSVLGEGGFGSVFKGWI--- 89
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
DE L P + G + + +K L+ H + + + Q+SH +L
Sbjct 90 -----------DEKTLAPTKP-GTGMVIAVKKLNQEGHQGHREWLAEVNYLGQLSHPYLV 137
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV-PMAW--KMVVAQQLASALSYLENK 728
+ G CV + ++V E++ G L+ L R H P++W +M +A A L++L +
Sbjct 138 RLVGYCVEDEQRLLVYEFMPRGSLENHLFRRSTHFQPLSWNLRMKIALGAAKGLAFLHSD 197
Query 729 --NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLA 780
+++ + N+LL + KLSD G+ + ++ + + A
Sbjct 198 KVKVIYRDFKTSNVLLD-------ANYDAKLSDFGLAKDGPTGDKSHVSTRVMGTYGYAA 250
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGE-----APLQSRSPSEKEH-FYQRQHRLP 834
PE L G L+T D + FG LLE+ P + E + + R+
Sbjct 251 PEYLATG--HLTTKSDVYSFGVVLLEMLSGRRALDKNRPTGEHNLVEWARPYLMSKRRIF 308
Query 835 EPSCPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+L ATL QC++ E RP+ ++ L +LQ
Sbjct 309 RILDARLGGQYSLAKAQKAATLALQCISVEAKNRPNMEQVVAVLEQLQ 356
>sp|P08630|BTKL_DROME Tyrosine-protein kinase Btk OS=Drosophila
melanogaster OX=7227 GN=Btk PE=2 SV=2
Length=786
Score = 273 bits (698), Expect = 1e-76, Method: Composition-based stats.
Identities = 96/363 (26%), Positives = 154/363 (42%), Gaps = 29/363 (8%)
Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
++ + + + + + + + C P R L + D
Sbjct 449 HTKVPQSHVKHYHIKQNARCEYYLSEKHCCETIPDLINYHRHNSGGLACRLKSSPCDRPV 508
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
+ D H L + +LG G FG V + + D AVK +K G
Sbjct 509 PPTAGLSHDKWEIHPMELMLMEELGSGQFGVVRRGKWRGSIDT-----AVKMMKE--GTM 561
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL-- 997
+ +E ++ L H ++++ G C + + +V EY+ GSL +YL RH L
Sbjct 562 SEDDFIEEAKVMTKLQHPNLVQLYGVCSK--HRPIYIVTEYMKHGSLLNYLRRHEKTLIG 619
Query 998 --AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
LL Q+ +GM YL +YIHRDLAARN L+ ++ +VK+ DFGLA+ V + + Y
Sbjct 620 NMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYVLD--DQY 677
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
P+ W PE L +F SDVW++GV ++E+ T +
Sbjct 678 TSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGK--------------MP 723
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
G++ + E ++RG L +P C E+Y +MK CW RP F L+ L V +
Sbjct 724 YGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLALVAQT 783
Query 1176 YQG 1178
Sbjct 784 LTD 786
Score = 268 bits (685), Expect = 7e-75, Method: Composition-based stats.
Identities = 85/440 (19%), Positives = 162/440 (37%), Gaps = 72/440 (16%)
Query 438 VAPPRLV-MSIRDGIHGPLLEPFVQAKLRP--EDGLYLIHWSTSHPYRLILTVAQRSQAP 494
V P L+ + + G + ++ L+ ++G +++ S++ L++ +
Sbjct 397 VKPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTK-GLYTLSLHTKVPQS 455
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
++ + I+Q ++ +L + G C C
Sbjct 456 ------HVKHYHIKQNARCEYYLSEKHCCETIPDLINYHRHNS--GGLACRLKSSPC--- 504
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
R P T LS + E+ + LG G V G+ R
Sbjct 505 ------------DRPVPPTAGLSH-DKWEIHPMELMLMEELGSGQFGVVRRGKWRGS--- 548
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+ +K++ F E A +M+++ H +L ++
Sbjct 549 ----------------------IDTAVKMMKEGTMS-EDDFIEEAKVMTKLQHPNLVQLY 585
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGHV--PMAWKMVVAQQLASALSYLENKNLVH 732
GVC + +VTEY++HG L +LRR + M + + Q++ ++YLE N +H
Sbjct 586 GVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIH 645
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGG 787
++ RN L+ G+ +K++D G+ L + I W PE L
Sbjct 646 RDLAARNCLV-------GSENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVL--N 696
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLT 845
S+ D W +G + EI G+ P +E QR L P+ ++ +
Sbjct 697 YTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVM 756
Query 846 SQCLTYEPTQRPSFRTILRD 865
C ++ P +RP+FR ++
Sbjct 757 KLCWSHGPEERPAFRVLMDQ 776
>sp|P15209|NTRK2_MOUSE BDNF/NT-3 growth factors receptor OS=Mus
musculus OX=10090 GN=Ntrk2 PE=1 SV=1
Length=821
Score = 274 bits (700), Expect = 1e-76, Method: Composition-based stats.
Identities = 109/334 (33%), Positives = 160/334 (48%), Gaps = 33/334 (10%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914
P I + + +T + P + + + R+LGEG FGKV L
Sbjct 496 GPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAE 555
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
CY+ + +VAVK LK D R + +E ++L L HEHI+K+ G C + L
Sbjct 556 CYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGD--PL 612
Query 975 QLVMEYVPLGSLRDYLPRHS--------------IGLAQLLLFAQQICEGMAYLHAQHYI 1020
+V EY+ G L +L H + +Q+L AQQI GM YL +QH++
Sbjct 613 IMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFV 672
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + KF
Sbjct 673 HRDLATRNCLVGENLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRKFTT 731
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS GV L+E+ T+ Q++ + E + +G L RP C
Sbjct 732 ESDVWSLGVVLWEIFTYGKQ--------------PWYQLSNNEVIECITQGRVLQRPRTC 777
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
P EVY LM CW+ E R +++ +L+ + +
Sbjct 778 PQEVYELMLGCWQREPHTRKNIKSIHTLLQNLAK 811
Score = 266 bits (679), Expect = 8e-74, Method: Composition-based stats.
Identities = 72/306 (24%), Positives = 124/306 (41%), Gaps = 48/306 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ + I LG+G V+ + + L P +D+ + V +K
Sbjct 532 IKRHNIVLKRELGEGAFGKVF----------------LAECYNLCPEQDK---ILVAVKT 572
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--- 700
L + + F+ A L++ + H H+ +GVCV G IMV EY++HG L+ +LR
Sbjct 573 LKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 632
Query 701 ---------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
+ + + +AQQ+A+ + YL +++ VH ++ RN L+ G
Sbjct 633 PDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV-------GE 685
Query 752 SPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ +K+ D G+ S + + I W+ PE + +T D W G L
Sbjct 686 NLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSLGVVLW 743
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
EI G+ P S +E + L P ++ L C EP R + ++I
Sbjct 744 EIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHTRKNIKSIH 803
Query 864 RDLTRL 869
L L
Sbjct 804 TLLQNL 809
>sp|Q16620|NTRK2_HUMAN BDNF/NT-3 growth factors receptor OS=Homo
sapiens OX=9606 GN=NTRK2 PE=1 SV=1
Length=822
Score = 274 bits (700), Expect = 1e-76, Method: Composition-based stats.
Identities = 109/334 (33%), Positives = 159/334 (48%), Gaps = 33/334 (10%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914
P I + + +T + P + + + R+LGEG FGKV L
Sbjct 497 GPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAE 556
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
CY+ + +VAVK LK D R + +E ++L L HEHI+K+ G C + L
Sbjct 557 CYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGD--PL 613
Query 975 QLVMEYVPLGSLRDYLPRHS--------------IGLAQLLLFAQQICEGMAYLHAQHYI 1020
+V EY+ G L +L H + +Q+L AQQI GM YL +QH++
Sbjct 614 IMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFV 673
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + KF
Sbjct 674 HRDLATRNCLVGENLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRKFTT 732
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS GV L+E+ T+ Q++ + E + +G L RP C
Sbjct 733 ESDVWSLGVVLWEIFTYGKQ--------------PWYQLSNNEVIECITQGRVLQRPRTC 778
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
P EVY LM CW+ E R + + +L+ + +
Sbjct 779 PQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAK 812
Score = 266 bits (679), Expect = 8e-74, Method: Composition-based stats.
Identities = 72/306 (24%), Positives = 123/306 (40%), Gaps = 48/306 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ + I LG+G V+ + + L P +D+ + V +K
Sbjct 533 IKRHNIVLKRELGEGAFGKVF----------------LAECYNLCPEQDK---ILVAVKT 573
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--- 700
L + + F+ A L++ + H H+ +GVCV G IMV EY++HG L+ +LR
Sbjct 574 LKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 633
Query 701 ---------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
+ + + +AQQ+A+ + YL +++ VH ++ RN L+ G
Sbjct 634 PDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV-------GE 686
Query 752 SPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ +K+ D G+ S + + I W+ PE + +T D W G L
Sbjct 687 NLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSLGVVLW 744
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
EI G+ P S +E + L P ++ L C EP R + + I
Sbjct 745 EIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIH 804
Query 864 RDLTRL 869
L L
Sbjct 805 TLLQNL 810
>sp|Q54H46|DRKA_DICDI Probable serine/threonine-protein kinase
drkA OS=Dictyostelium discoideum OX=44689 GN=drkA PE=3 SV=1
Length=642
Score = 269 bits (688), Expect = 2e-76, Method: Composition-based stats.
Identities = 77/304 (25%), Positives = 132/304 (43%), Gaps = 34/304 (11%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
N + D +K +G+G++G+V L + G VAVK L A
Sbjct 352 YYKPDKNDYTQIKDGKDIDIHQIKIGVRIGKGNYGEVYLGTWR------GSQVAVKKLPA 405
Query 935 -DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993
+ + +EI++++ L H ++I++ G C + + + EY+P GSL L
Sbjct 406 HNINENILKEFHREINLMKNLRHPNVIQFLGSCLIPPD--ICICTEYMPRGSLYSILHDQ 463
Query 994 SIG--LAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
++ + L+ +G+ YLH +HRDL + N+L+D + VK+ DFGL+
Sbjct 464 ALQLQWSLLIKMMIDAAKGVIYLHNSTPVILHRDLKSHNLLVDENWKVKVADFGLSTIEQ 523
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKF 1108
+G W +PE L+ ++ +DV+SFG+ L+E T D PP +
Sbjct 524 QG-----ATMTACGTPCWTSPEVLRSQRYTEKADVYSFGIILWECATRQDPYFGIPPFQV 578
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
+ +G G R P P P + L+ +C S RPT E +
Sbjct 579 IFAVG---------------REGMRPPVPQNGPPKYIQLLIDCLNENPSHRPTMEQCLER 623
Query 1169 LKTV 1172
L+++
Sbjct 624 LESI 627
Score = 229 bits (584), Expect = 1e-62, Method: Composition-based stats.
Identities = 67/356 (19%), Positives = 118/356 (33%), Gaps = 55/356 (15%)
Query 537 LLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLG 596
L CF L R N G + +D +I +G
Sbjct 332 GLLIIGGCFLLIR----------NRYRSSGYYKPDKNDYTQIKDGKDIDIHQIKIGVRIG 381
Query 597 QGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL--DPSHHDIALA 654
+G VY G R +V +K L + +I
Sbjct 382 KGNYGEVYLGTWRGS--------------------------QVAVKKLPAHNINENILKE 415
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F+ +LM + H ++ G C+ P+ + TEY+ G L L + + + + +
Sbjct 416 FHREINLMKNLRHPNVIQFLGSCLIPPDICICTEYMPRGSLYSILHDQALQLQWSLLIKM 475
Query 715 AQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--GALSRE 770
A + YL N ++H ++ N+L+ + +K++D G+ +
Sbjct 476 MIDAAKGVIYLHNSTPVILHRDLKSHNLLVDE-------NWKVKVADFGLSTIEQQGATM 528
Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829
W +PE L + + D + FG L E C + P P + R
Sbjct 529 TACGTPCWTSPEVLR--SQRYTEKADVYSFGIILWE-CATRQDPYFGIPPFQVIFAVGRE 585
Query 830 --QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
+ +P+ P+ L CL P+ RP+ L L + +D+ V
Sbjct 586 GMRPPVPQNGPPKYIQLLIDCLNENPSHRPTMEQCLERLESIDSSGYSDLQYVRQQ 641
>sp|P43293|PBL11_ARATH Probable serine/threonine-protein kinase
PBL11 OS=Arabidopsis thaliana OX=3702 GN=PBL11 PE=1 SV=2
Length=389
Score = 261 bits (666), Expect = 2e-76, Method: Composition-based stats.
Identities = 86/329 (26%), Positives = 143/329 (43%), Gaps = 18/329 (5%)
Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD-----PTN 920
+ + + N + + R + +GEG FG V D P+
Sbjct 37 FSYMPRTEGEILQNANLKNFSLSELKSATRNFRPDSVVGEGGFGCVFKGWIDESSLAPSK 96
Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
GTG ++AVK L + HR W EI+ L L H +++K G C ++ + LV E+
Sbjct 97 PGTGIVIAVKRLNQEGFQGHRE-WLAEINYLGQLDHPNLVKLIGYCLEEEHR--LLVYEF 153
Query 981 VPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDN 1033
+ GSL ++L R + + A G+A+LH I+RD A N+LLD+
Sbjct 154 MTRGSLENHLFRRGTFYQPLSWNTRVRMALGAARGLAFLHNAQPQVIYRDFKASNILLDS 213
Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
+ K+ DFGLA+ P G + V + APE L SDV+SFGV L E
Sbjct 214 NYNAKLSDFGLARDGPMGDNSH-VSTRVMGTQGYAAPEYLATGHLSVKSDVYSFGVVLLE 272
Query 1094 LLTHCDS-SQSPPTKFLELIGIAQGQMTV-LRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
LL+ + ++ P L+ A+ +T RL +++ + ++ L +C
Sbjct 273 LLSGRRAIDKNQPVGEHNLVDWARPYLTNKRRLLRVMDPRLQGQYSLTRALKIAVLALDC 332
Query 1152 WETEASFRPTFENLIPILKTVHEKYQGQA 1180
+A RPT ++ ++ +H + +
Sbjct 333 ISIDAKSRPTMNEIVKTMEELHIQKEASK 361
Score = 235 bits (600), Expect = 3e-67, Method: Composition-based stats.
Identities = 70/367 (19%), Positives = 128/367 (35%), Gaps = 55/367 (15%)
Query 565 RGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
R + NL S + + S +G+G V++G +
Sbjct 42 RTEGEILQNANLKNFSLSELKSATRNFRPDSVVGEGGFGCVFKGWI-------------- 87
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
DE L P + G + + +K L+ + + + Q+ H +L + G C+
Sbjct 88 DESSLAPSKP-GTGIVIAVKRLNQEGFQGHREWLAEINYLGQLDHPNLVKLIGYCLEEEH 146
Query 683 NIMVTEYVEHGPLDVWLRRERG---HVPMAWKMVVAQQLASALSYLEN--KNLVHGNVCG 737
++V E++ G L+ L R + ++ +A A L++L N +++ +
Sbjct 147 RLLVYEFMTRGSLENHLFRRGTFYQPLSWNTRVRMALGAARGLAFLHNAQPQVIYRDFKA 206
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSL 791
NILL ++ KLSD G+ + + + APE L G L
Sbjct 207 SNILLD-------SNYNAKLSDFGLARDGPMGDNSHVSTRVMGTQGYAAPEYLATG--HL 257
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ------RQHRLPEPSCPQL---- 841
S D + FG LLE+ A +++ E + RL P+L
Sbjct 258 SVKSDVYSFGVVLLELLSGRRAIDKNQPVGEHNLVDWARPYLTNKRRLLRVMDPRLQGQY 317
Query 842 --------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFH 893
A L C++ + RP+ I++ + L A NP +
Sbjct 318 SLTRALKIAVLALDCISIDAKSRPTMNEIVKTMEELHIQKEASKEQQNPQISIDNIINKS 377
Query 894 KRYLKKI 900
+ +
Sbjct 378 PQAVNYP 384
>sp|O09127|EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus musculus
OX=10090 GN=Epha8 PE=1 SV=2
Length=1004
Score = 276 bits (707), Expect = 2e-76, Method: Composition-based stats.
Identities = 93/316 (29%), Positives = 141/316 (45%), Gaps = 20/316 (6%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+ S + + +G G G+V VA+KALKA
Sbjct 612 PHTYEEPGRAGRSFTREIEASRIHIEKIIGSGESGEVCYGRLQVPGQRD-VPVAIKALKA 670
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994
+ R + E I+ H +II+ +G + +V EY+ GSL +L H
Sbjct 671 GYTERQRQDFLSEAAIMGQFDHPNIIRLEGVVTRG--RLAMIVTEYMENGSLDAFLRTHD 728
Query 995 --IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
+ QL+ + + GM YL YIHRDLAARNVL+D + K+ DFGL++A+ +
Sbjct 729 GQFTIVQLVGMLRGVGAGMRYLSDLGYIHRDLAARNVLVDGRLVCKVSDFGLSRALEDDP 788
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
E G P+ W APE + F ASDVWSFGV ++E+L + +
Sbjct 789 EAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGER------------ 836
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
MT + +E G RLP P CP ++ LM +CW + + RP F +++ +L +
Sbjct 837 --PYWNMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFAHVVSVLDAL 894
Query 1173 -HEKYQGQAPSVFSVC 1187
H +A + S C
Sbjct 895 VHSPESLRATATVSRC 910
Score = 256 bits (655), Expect = 2e-69, Method: Composition-based stats.
Identities = 77/339 (23%), Positives = 129/339 (38%), Gaps = 46/339 (14%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
++ I +G G V GRL+V G +++ V
Sbjct 626 TREIEASRIHIEKIIGSGESGEVCYGRLQVPGQ---------------------RDVPVA 664
Query 641 LKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+K L + + F A++M Q H ++ + GV RG ++VTEY+E+G LD +L
Sbjct 665 IKALKAGYTERQRQDFLSEAAIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDAFL 724
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R G + + + + + + + YL + +H ++ RN+L+ K+SD
Sbjct 725 RTHDGQFTIVQLVGMLRGVGAGMRYLSDLGYIHRDLAARNVLVD-------GRLVCKVSD 777
Query 760 PGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
G+ E I W APE + + S+A D W FG + E+ GE
Sbjct 778 FGLSRALEDDPEAAYTTAGGKIPIRWTAPEAIA--FRTFSSASDVWSFGVVMWEVLAYGE 835
Query 813 APLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P + + + + +RLP CP+ L L C + QRP F ++ L L
Sbjct 836 RPYWNMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFAHVVSVLDALV 895
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
+ T + + DL G G
Sbjct 896 HSPESLRATATVSRCPPP------AFARSCFDLRAGGSG 928
>sp|P41243|MATK_RAT Megakaryocyte-associated tyrosine-protein
kinase OS=Rattus norvegicus OX=10116 GN=Matk PE=2 SV=1
Length=467
Score = 263 bits (673), Expect = 2e-76, Method: Composition-based stats.
Identities = 102/423 (24%), Positives = 171/423 (40%), Gaps = 71/423 (17%)
Query 446 SIRDGIHGPLLEPFVQAKLRP-EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
S+ HG + +L+P EDGL+L+ S HP +L V+
Sbjct 77 SLMPWFHGKISGQEAIQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVI---------H 127
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ + +DG ++ F ++ ++ G C L + Q +++ +
Sbjct 128 YRVLHRDGHLTID-EAVCFCNLMDMVEHYTRDK---GAICTKLVKPKRKQGAKSAEEELA 183
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
+ +D + +T + +G+G V +G +
Sbjct 184 KAG--------------WLLDLQHLTLGAQIGEGEFGAVLQGEYLGQ------------- 216
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+V +K + A AF + ++M+++ H +L + GV +
Sbjct 217 -------------KVAVKNIKCDVT--AQAFLDETAVMTKLQHRNLVRLLGVILHHG-LY 260
Query 685 MVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+V E+V G L +LR R R V + + A +A + YLE+K LVH ++ RNIL++
Sbjct 261 IVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVS 320
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFG 801
+A K+SD G+ L + R+P W APE L G S+ D W FG
Sbjct 321 EDLVA-------KVSDFGLAKAELRKGLDSSRLPVKWTAPEALKNG--RFSSKSDVWSFG 371
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSF 859
L E+ G AP S E ++ +R+ P SCP + TL C EP++RP F
Sbjct 372 VLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPDSCPGPVHTLMGSCWEAEPSRRPPF 431
Query 860 RTI 862
R I
Sbjct 432 RKI 434
Score = 263 bits (672), Expect = 3e-76, Method: Composition-based stats.
Identities = 106/355 (30%), Positives = 160/355 (45%), Gaps = 45/355 (13%)
Query 821 SEKEHFY--QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ H+ R L L R T+L
Sbjct 123 RDVIHYRVLHRDGHLTIDEAVCFCNLMDM-------VEHYTRDKGAICTKLVKPKRKQGA 175
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
+ A + ++L +GEG FG V Y G+ VAVK +K D
Sbjct 176 KSAEEELAKAGWLLDLQHLTLGAQIGEGEFGAVLQGEYL------GQKVAVKNIKCDVTA 229
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---I 995
Q + E ++ L H ++++ G G L +VME+V G+L ++L +
Sbjct 230 Q---AFLDETAVMTKLQHRNLVRLLGVILHHG---LYIVMEHVSKGNLVNFLRTRGRALV 283
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK-AVPEGHEY 1054
+QLL FA + EGM YL ++ +HRDLAARN+L+ D + K+ DFGLAK + +G +
Sbjct 284 STSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAELRKGLDS 343
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
R+ PV W APE LK +F SDVWSFGV L+E+ ++ +
Sbjct 344 SRL------PVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRA-------------- 383
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+M++ ++E +E+G R+ PD CP V+ LM +CWE E S RP F ++ L
Sbjct 384 PYPKMSLKEVSEAVEKGYRMEPPDSCPGPVHTLMGSCWEAEPSRRPPFRKIVEKL 438
>sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens
OX=9606 GN=EPHB4 PE=1 SV=2
Length=987
Score = 276 bits (706), Expect = 3e-76, Method: Composition-based stats.
Identities = 76/274 (28%), Positives = 129/274 (47%), Gaps = 21/274 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG+V VA+K LK + R + E I+ H +II+
Sbjct 621 IGAGEFGEVCRGRLKAPGKKES-CVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRL 679
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+G + ++ E++ G+L +L + QL+ + I GM YL Y+
Sbjct 680 EGVVT--NSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYV 737
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKF 1078
HRDLAARN+L++++ + K+ DFGL++ + E Y G P+ W APE + KF
Sbjct 738 HRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKF 797
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
ASD WS+G+ ++E+++ + M+ + +E+ RLP P
Sbjct 798 TSASDAWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIEQDYRLPPPP 843
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
CP ++ LM +CW+ + + RP F ++ L +
Sbjct 844 DCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKM 877
Score = 262 bits (669), Expect = 2e-71, Method: Composition-based stats.
Identities = 77/362 (21%), Positives = 136/362 (38%), Gaps = 60/362 (17%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G V GRL+ G +E V +
Sbjct 608 KEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGK---------------------KESCVAI 646
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV +++TE++E+G LD +LR
Sbjct 647 KTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLR 706
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G + + + + +AS + YL + VH ++ RNIL+ ++ K+SD
Sbjct 707 LNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVN-------SNLVCKVSDF 759
Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ +IP W APE + ++A D W +G + E+ G
Sbjct 760 GLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIA--FRKFTSASDAWSYGIVMWEVMSFG 817
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P S + + ++ +RLP P L L C + RP F ++ L ++
Sbjct 818 ERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKM 877
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+ + + + AS P + ++ FG V + A+
Sbjct 878 IRNPASLKIVARENGGASHPLLDQRQPHYS-------AFGSVGEWLR-----------AI 919
Query 930 KA 931
K
Sbjct 920 KM 921
>sp|Q07498|EPHB3_CHICK Ephrin type-B receptor 3 (Fragment) OS=Gallus
gallus OX=9031 GN=EPHB3 PE=2 SV=1
Length=988
Score = 276 bits (706), Expect = 3e-76, Method: Composition-based stats.
Identities = 78/309 (25%), Positives = 140/309 (45%), Gaps = 23/309 (7%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-V 927
++ + ++ +K +G G FG+V G E+ V
Sbjct 595 MKVYIDPFTYEDPNEAVREFAKEIDISCVKIEEVIGAGEFGEVCRGRLK--LPGRREIFV 652
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK + R + E I+ H +II +G + + ++ E++ +L
Sbjct 653 AIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIHLEGVVTKS--RPVMIITEFMENCALD 710
Query 988 DYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL+
Sbjct 711 SFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLS 770
Query 1046 KAVPEG--HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
+ + + Y G P+ W APE + KF ASDVWS+G+ ++E++++ +
Sbjct 771 RFLEDDPADPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGER--- 827
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163
M+ + +E+ RLP P CP ++ LM +CW + + RP F
Sbjct 828 -----------PYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFA 876
Query 1164 NLIPILKTV 1172
++ L +
Sbjct 877 QIVNTLDKL 885
Score = 260 bits (664), Expect = 9e-71, Method: Composition-based stats.
Identities = 76/348 (22%), Positives = 134/348 (39%), Gaps = 42/348 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G V GRL++ G +E+ V +
Sbjct 616 KEIDISCVKIEEVIGAGEFGEVCRGRLKLPGR---------------------REIFVAI 654
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + F AS+M Q H ++ + GV + +++TE++E+ LD +LR
Sbjct 655 KTLKVGYTERQRRDFLSEASIMGQFDHPNIIHLEGVVTKSRPVMIITEFMENCALDSFLR 714
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD
Sbjct 715 LNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 767
Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ +IP W APE + ++A D W +G + E+ G
Sbjct 768 GLSRFLEDDPADPTYTSSLGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYG 825
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P S + + ++ +RLP P CP L L C + RP F I+ L +L
Sbjct 826 ERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFAQIVNTLDKL 885
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917
+ + + + S S P + + + Y
Sbjct 886 IRNAASLKVIASVQSGVSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYK 933
>sp|Q55GU0|Y9955_DICDI Probable serine/threonine-protein kinase
DDB_G0267514 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0267514
PE=3 SV=1
Length=916
Score = 275 bits (702), Expect = 4e-76, Method: Composition-based stats.
Identities = 90/321 (28%), Positives = 139/321 (43%), Gaps = 30/321 (9%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915
+ + ++ + V + LK LGEG FG V
Sbjct 621 NNHSPNQYNNQGNILKNSGSVVEPPSQQQQYFSDIEISFSELKISSKLGEGTFGVVYKGL 680
Query 916 YDPTNDGTGEMVAVKALK--ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
+ G VA+K +K D Q +++E+ IL L H +I+ C +
Sbjct 681 WR------GSSVAIKQIKINEDVNNQVLEEFRKELTILSRLRHPNIVLLMAACT--APPN 732
Query 974 LQLVMEYVPLGSLRDYLPRHSIGLAQLL--LFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031
L + EY+P GSL D L I + L A QI +GM YLH IHRD+ + N+LL
Sbjct 733 LCFITEYLPGGSLYDALHSKKIKMNMQLYKKLAIQIAQGMNYLHLSGVIHRDIKSLNLLL 792
Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091
D VKI DFGL+K + E + + SP+ W +PE L + DV++FG+ L
Sbjct 793 DEHMNVKICDFGLSKLKSKSTE---MTKSIGSPI-WMSPELLMGEDYTEKVDVYAFGIIL 848
Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
+EL T P L+ + +A T + R P P+ P ++ HL++ C
Sbjct 849 WELGTG-----ELPYSGLDSVQLALAVTT---------KSLRPPIPNAWPYQLSHLIQAC 894
Query 1152 WETEASFRPTFENLIPILKTV 1172
W + RP+F ++ +L +
Sbjct 895 WHQDPLKRPSFTEILNLLNEI 915
Score = 254 bits (649), Expect = 4e-69, Method: Composition-based stats.
Identities = 69/328 (21%), Positives = 123/328 (38%), Gaps = 45/328 (14%)
Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
Q N++ G+ P + S + E+ S LG+GT VY+G R
Sbjct 625 PNQYNNQGNILKNSGSVVEPPSQQQQYFSDIEISFSELKISSKLGEGTFGVVYKGLWRGS 684
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETASLMSQVSHT 668
V +K + + ++ + F + +++S++ H
Sbjct 685 S--------------------------VAIKQIKINEDVNNQVLEEFRKELTILSRLRHP 718
Query 669 HLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK 728
++ + C P +TEY+ G L L ++ + M +A Q+A ++YL
Sbjct 719 NIVLLMAACTAPPNLCFITEYLPGGSLYDALHSKKIKMNMQLYKKLAIQIAQGMNYLHLS 778
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---WLAPECLP 785
++H ++ N+LL +K+ D G+ E + I W++PE L
Sbjct 779 GVIHRDIKSLNLLLDE-------HMNVKICDFGLSKLKSKSTEMTKSIGSPIWMSPELLM 831
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---QHRLPEPSCPQLA 842
G + +D + FG L E+ GE P + + +P QL+
Sbjct 832 G--EDYTEKVDVYAFGIILWELG-TGELPYSGLDSVQLALAVTTKSLRPPIPNAWPYQLS 888
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
L C +P +RPSF IL L +
Sbjct 889 HLIQACWHQDPLKRPSFTEILNLLNEIP 916
>sp|G5ECJ6|CSK1_CAEEL Tyrosine-protein kinase csk-1 OS=Caenorhabditis
elegans OX=6239 GN=csk-1 PE=1 SV=1
Length=539
Score = 265 bits (677), Expect = 4e-76, Method: Composition-based stats.
Identities = 86/276 (31%), Positives = 135/276 (49%), Gaps = 29/276 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V L Y VA+K G E + L H +++
Sbjct 288 TIGHGEFGDVRLGTYK------NRKVALKV-SKRHGNGMLDSLLDEAKFMVGLSHPNLVT 340
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQH 1018
G D + ++ ++ EY+ G+L D L RH++ QL++FA IC+GM YL ++
Sbjct 341 LVGVVLD--DVNVYMITEYMANGNLIDLLRSRGRHALERRQLMMFAMDICQGMCYLESKQ 398
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRDLAARNVLLD+D + K+ DFGLAK + + G P+ W APE L+ +F
Sbjct 399 IVHRDLAARNVLLDDDLVAKVSDFGLAK---KANSQSHDSASGKFPIKWTAPEALRHSQF 455
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SDVWSFG+ L+E+ + + ++ + + +E+G R+ P+
Sbjct 456 TTKSDVWSFGILLWEIFSFGR--------------VPYPRIPIQDVVRYIEKGYRMEAPE 501
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
CP E++ +M W A RP+F ++ L T+
Sbjct 502 GCPPEIFKVMNETWALSAQDRPSFGQVLQRLTTIRN 537
Score = 256 bits (654), Expect = 6e-73, Method: Composition-based stats.
Identities = 94/438 (21%), Positives = 163/438 (37%), Gaps = 59/438 (13%)
Query 446 SIRDGIHGPLLEPFVQAKLR-PEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504
+ + H + + LR DG +L+ ST+ P L ++ ++
Sbjct 147 NHQPWFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSF---------HGKVEH 197
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ IEQ G + F ++ +L + + A C L + + S+
Sbjct 198 YRIEQTSGGQLTCDKEEYFSNLTQLVSHYKRD---ADGLCHRLVTPIICETATFSSNGSS 254
Query 565 RGARASPRTLNLSQLSFHR----VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620
+S L F + +I +G G +V G +
Sbjct 255 SFGSSSTVDLEDRTSVFRHAGLVISSNDIDVGDTIGHGEFGDVRLGTYKNR--------- 305
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680
+V LKV + + + + A M +SH +L + GV +
Sbjct 306 -----------------KVALKVSKRHGNGMLDSLLDEAKFMVGLSHPNLVTLVGVVLDD 348
Query 681 PENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRN 739
M+TEY+ +G L LR H + M+ A + + YLE+K +VH ++ RN
Sbjct 349 VNVYMITEYMANGNLIDLLRSRGRHALERRQLMMFAMDICQGMCYLESKQIVHRDLAARN 408
Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER----IPWLAPECLPGGANSLSTAM 795
+LL +A K+SD G+ A S+ I W APE L + +T
Sbjct 409 VLLDDDLVA-------KVSDFGLAKKANSQSHDSASGKFPIKWTAPEALRH--SQFTTKS 459
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEP 853
D W FG L EI G P + + ++ +R+ PE P++ + ++
Sbjct 460 DVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSA 519
Query 854 TQRPSFRTILRDLTRLQP 871
RPSF +L+ LT ++
Sbjct 520 QDRPSFGQVLQRLTTIRN 537
>sp|Q9SFT7|PBL26_ARATH Probable serine/threonine-protein kinase
PBL26 OS=Arabidopsis thaliana OX=3702 GN=PBL26 PE=2 SV=1
Length=414
Score = 261 bits (666), Expect = 4e-76, Method: Composition-based stats.
Identities = 86/284 (30%), Positives = 131/284 (46%), Gaps = 18/284 (6%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
++ +GEG FG+V Y + TG +VAVK L + G Q + E+ +L L+
Sbjct 78 NFRQECLIGEGGFGRV----YKGKLEKTGMIVAVKQLDRN-GLQGNKEFIVEVLMLSLLH 132
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEG 1010
H+H++ G C D ++ LV EY+ GSL D+L + + + A G
Sbjct 133 HKHLVNLIGYCADGDQR--LLVYEYMSRGSLEDHLLDLTPDQIPLDWDTRIRIALGAAMG 190
Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH + I+RDL A N+LLD + K+ DFGLAK P G + + V +
Sbjct 191 LEYLHDKANPPVIYRDLKAANILLDGEFNAKLSDFGLAKLGPVGDKQH-VSSRVMGTYGY 249
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQ-MTVLRLT 1125
APE + + SDV+SFGV L EL+T + P L+ AQ R
Sbjct 250 CAPEYQRTGQLTTKSDVYSFGVVLLELITGRRVIDTTRPKDEQNLVTWAQPVFKEPSRFP 309
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
EL + P+K + + C + EA+ RP +++ L
Sbjct 310 ELADPSLEGVFPEKALNQAVAVAAMCLQEEATVRPLMSDVVTAL 353
Score = 238 bits (606), Expect = 7e-68, Method: Composition-based stats.
Identities = 81/375 (22%), Positives = 130/375 (35%), Gaps = 66/375 (18%)
Query 546 SLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNV 603
+ P+ N + + SF + K Q +G+G V
Sbjct 35 NKTHPENPKTVNEQNK-NNDEDKEVTNNIAAQTFSFRELATATKNFRQECLIGEGGFGRV 93
Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663
Y+G+L G + V +K LD + F ++S
Sbjct 94 YKGKLEKTG------------------------MIVAVKQLDRNGLQGNKEFIVEVLMLS 129
Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KMVVAQQLAS 720
+ H HL + G C G + ++V EY+ G L+ L +P+ W ++ +A A
Sbjct 130 LLHHKHLVNLIGYCADGDQRLLVYEYMSRGSLEDHLLDLTPDQIPLDWDTRIRIALGAAM 189
Query 721 ALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERV--- 773
L YL +K +++ ++ NILL KLSD G+ LG + ++ V
Sbjct 190 GLEYLHDKANPPVIYRDLKAANILLD-------GEFNAKLSDFGLAKLGPVGDKQHVSSR 242
Query 774 --ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
+ APE G L+T D + FG LLE+ +R E+ Q
Sbjct 243 VMGTYGYCAPEYQRTG--QLTTKSDVYSFGVVLLELITGRRVIDTTRPKDEQNLVTWAQP 300
Query 832 ------RLPEPSCPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
R PE + P L + + CL E T RP ++ L L
Sbjct 301 VFKEPSRFPELADPSLEGVFPEKALNQAVAVAAMCLQEEATVRPLMSDVVTALGFLGTAP 360
Query 874 LADVLTVNPDSPASD 888
+ + D P
Sbjct 361 DGSISVPHYDDPPQP 375
>sp|Q8RWL6|STY17_ARATH Serine/threonine-protein kinase STY17 OS=Arabidopsis
thaliana OX=3702 GN=STY17 PE=1 SV=1
Length=570
Score = 266 bits (679), Expect = 5e-76, Method: Composition-based stats.
Identities = 78/304 (26%), Positives = 144/304 (47%), Gaps = 29/304 (10%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CG 937
V + +D + LK + + G +G++ Y + VA+K LK +
Sbjct 274 CVEIPTDGTDEWEIDMKQLKIEKKVACGSYGELFRGTY------CSQEVAIKILKPERVN 327
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995
+ + QE+ I+R + H++++++ G C +L +V E++ GS+ D+L +H
Sbjct 328 AEMLREFSQEVYIMRKVRHKNVVQFIGACTRS--PNLCIVTEFMTRGSIYDFLHKHKGVF 385
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ LL A + +GM YLH + IHRDL N+L+D +VK+ DFG+A+ E
Sbjct 386 KIQSLLKVALDVSKGMNYLHQNNIIHRDLKTANLLMDEHEVVKVADFGVARVQTESG--- 442
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
V W APE ++ + + +DV+S+ + L+ELLT P +L + A
Sbjct 443 -VMTAETGTYRWMAPEVIEHKPYDHRADVFSYAIVLWELLTG-----ELPYSYLTPLQAA 496
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
G ++++G R P + ++ L++ CW+ + + RP F +I +L + +
Sbjct 497 VG---------VVQKGLRPKIPKETHPKLTELLEKCWQQDPALRPNFAEIIEMLNQLIRE 547
Query 1176 YQGQ 1179
Sbjct 548 VGDD 551
Score = 233 bits (593), Expect = 2e-64, Method: Composition-based stats.
Identities = 58/314 (18%), Positives = 117/314 (37%), Gaps = 44/314 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D K++ + G+ ++ G + V +
Sbjct 285 WEIDMKQLKIEKKVACGSYGELFRGTYCSQ--------------------------EVAI 318
Query 642 KVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
K+L P + ++ F + +M +V H ++ G C R P +VTE++ G + +L
Sbjct 319 KILKPERVNAEMLREFSQEVYIMRKVRHKNVVQFIGACTRSPNLCIVTEFMTRGSIYDFL 378
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ +G + + VA ++ ++YL N++H ++ N+L+ +K++D
Sbjct 379 HKHKGVFKIQSLLKVALDVSKGMNYLHQNNIIHRDLKTANLLMDE-------HEVVKVAD 431
Query 760 PGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
GV W+APE + D + + L E+ GE P
Sbjct 432 FGVARVQTESGVMTAETGTYRWMAPEVIEH--KPYDHRADVFSYAIVLWELL-TGELPYS 488
Query 817 SRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
+P + + ++P+ + P+L L +C +P RP+F I+ L +L
Sbjct 489 YLTPLQAAVGVVQKGLRPKIPKETHPKLTELLEKCWQQDPALRPNFAEIIEMLNQLIREV 548
Query 874 LADVLTVNPDSPAS 887
D +
Sbjct 549 GDDERHKDKHGGYF 562
>sp|Q9SRH7|PBL35_ARATH Serine/threonine-protein kinase PBL35 OS=Arabidopsis
thaliana OX=3702 GN=PBL35 PE=1 SV=1
Length=490
Score = 263 bits (673), Expect = 5e-76, Method: Composition-based stats.
Identities = 89/332 (27%), Positives = 140/332 (42%), Gaps = 16/332 (5%)
Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVS 912
P + + + + + + R + LGEG FG V
Sbjct 92 PVSSTTTTSNAESSLSTPIISEELNIYSHLKKFSFIDLKLATRNFRPESLLGEGGFGCVF 151
Query 913 LYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
+ P GTG VAVK L D G Q W EI+ L L H +++K G C
Sbjct 152 KGWVEENGTAPVKPGTGLTVAVKTLNPD-GLQGHKEWLAEINYLGNLLHPNLVKLVGYCI 210
Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLLFAQQICEGMAYLHA---QHYIHR 1022
+ ++ LV E++P GSL ++L R S+ + + A +G+++LH + I+R
Sbjct 211 EDDQR--LLVYEFMPRGSLENHLFRRSLPLPWSIRMKIALGAAKGLSFLHEEALKPVIYR 268
Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082
D N+LLD + K+ DFGLAK P+ + + V + APE + S
Sbjct 269 DFKTSNILLDGEYNAKLSDFGLAKDAPDEGKTH-VSTRVMGTYGYAAPEYVMTGHLTSKS 327
Query 1083 DVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQ-MTVLRLTELLERGERLPRPDKC 1140
DV+SFGV L E+LT S ++ P L+ A+ + R LL+ K
Sbjct 328 DVYSFGVVLLEMLTGRRSMDKNRPNGEHNLVEWARPHLLDKRRFYRLLDPRLEGHFSVKG 387
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+V L C ++ RP ++ +LK +
Sbjct 388 AQKVTQLAAQCLSRDSKIRPKMSEVVEVLKPL 419
Score = 250 bits (638), Expect = 3e-71, Method: Composition-based stats.
Identities = 66/341 (19%), Positives = 123/341 (36%), Gaps = 53/341 (16%)
Query 575 NLSQLSFH--RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
+L + SF ++ + S LG+G V++G + G+ +
Sbjct 120 HLKKFSFIDLKLATRNFRPESLLGEGGFGCVFKGWVEENGTAPVKP-------------- 165
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
G L V +K L+P + + + + H +L + G C+ + ++V E++
Sbjct 166 -GTGLTVAVKTLNPDGLQGHKEWLAEINYLGNLLHPNLVKLVGYCIEDDQRLLVYEFMPR 224
Query 693 GPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAE 749
G L+ L R +P + +M +A A LS+L K +++ + NILL
Sbjct 225 GSLENHLFRRSLPLPWSIRMKIALGAAKGLSFLHEEALKPVIYRDFKTSNILLD------ 278
Query 750 GTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
KLSD G+ A + + APE + G L++ D + FG
Sbjct 279 -GEYNAKLSDFGLAKDAPDEGKTHVSTRVMGTYGYAAPEYVMTG--HLTSKSDVYSFGVV 335
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS------------------CPQLATLT 845
LLE+ + ++R E + L + ++ L
Sbjct 336 LLEMLTGRRSMDKNRPNGEHNLVEWARPHLLDKRRFYRLLDPRLEGHFSVKGAQKVTQLA 395
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
+QCL+ + RP ++ L L + +
Sbjct 396 AQCLSRDSKIRPKMSEVVEVLKPLPHLKDMASASYYFQTMQ 436
>sp|Q62413|EPHA6_MOUSE Ephrin type-A receptor 6 OS=Mus musculus
OX=10090 GN=Epha6 PE=1 SV=2
Length=1035
Score = 276 bits (706), Expect = 5e-76, Method: Composition-based stats.
Identities = 84/352 (24%), Positives = 147/352 (42%), Gaps = 57/352 (16%)
Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922
++ + D + ++ R +G G FG+V T
Sbjct 596 HLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLK-TPGK 654
Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE----------- 971
VA+K LK + R + +E I+ H +II+ +G +
Sbjct 655 REIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPS 714
Query 972 -----------------------------KSLQLVMEYVPLGSLRDYLPRHS--IGLAQL 1000
+ + +V+EY+ GSL +L +H + QL
Sbjct 715 FLRAGFLNGIQAPHPVTAGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQL 774
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL++ + + E
Sbjct 775 VGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTG 834
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
G P+ W APE + KF ASD WS+G+ ++E++++ + +M+
Sbjct 835 GKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYGER--------------PYWEMS 880
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ +E G RLP P CP ++ LM +CW+ E + RP F +++ L +
Sbjct 881 NQDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFLDKL 932
Score = 260 bits (665), Expect = 1e-70, Method: Composition-based stats.
Identities = 87/404 (22%), Positives = 135/404 (33%), Gaps = 88/404 (22%)
Query 570 SPRTLNLSQLSFHR----VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
P T L+ H +D I +G G V GRL+ G
Sbjct 607 DPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGK------------ 654
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVR----- 679
+E+ V +K L H D F AS+M Q H ++ + GV +
Sbjct 655 ---------REIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPA 705
Query 680 -------------------------------------GPENIMVTEYVEHGPLDVWLRRE 702
G ++V EY+E+G LD +LR+
Sbjct 706 IGVEAFCPSFLRAGFLNGIQAPHPVTAGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKH 765
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
GH + + + + +AS + YL + VH ++ RNIL+ ++ K+SD G+
Sbjct 766 DGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVN-------SNLVCKVSDFGL 818
Query 763 GL-------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
A + I W APE + S+A D W +G + E+ GE P
Sbjct 819 SRVLEDDPEAAYTTTGGKIPIRWTAPEAIA--YRKFSSASDAWSYGIVMWEVMSYGERPY 876
Query 816 QSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
S + + +RL P P L L C E RP F I+ L +L +
Sbjct 877 WEMSNQDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNP 936
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917
A V + Y + + + Y
Sbjct 937 SALHTLVEDILVMPESPGDVPEYPLFVTVGDW--LDSIKMGQYK 978
>sp|Q03142|FGFR4_MOUSE Fibroblast growth factor receptor 4 OS=Mus
musculus OX=10090 GN=Fgfr4 PE=1 SV=3
Length=799
Score = 271 bits (693), Expect = 9e-76, Method: Composition-based stats.
Identities = 100/304 (33%), Positives = 147/304 (48%), Gaps = 38/304 (13%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE---MVAVKALKADCGPQHRSGWKQ 946
F + L + LGEG FG+V + + VAVK LK + + +
Sbjct 457 WEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPSRPDQTSTVAVKMLKDNASDKDLADLVS 516
Query 947 EIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-------------- 991
E+++++ + H++II G C +G L +++E G+LR++L
Sbjct 517 EMEVMKLIGRHKNIINLLGVCTQEG--PLYVIVECAAKGNLREFLRARRPPGPDLSPDGP 574
Query 992 ---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ V
Sbjct 575 RSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDDVMKIADFGLARGV 634
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
+YY+ +G PV W APE L + + + SDVWSF + L+E+ T
Sbjct 635 HH-IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFEILLWEIFT------------ 681
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
L G + V L LL G R+ RP CP E+Y LM+ CW S RPTF+ L+
Sbjct 682 --LGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRECWHAAPSQRPTFKQLVEA 739
Query 1169 LKTV 1172
L V
Sbjct 740 LDKV 743
Score = 228 bits (580), Expect = 5e-61, Method: Composition-based stats.
Identities = 64/315 (20%), Positives = 111/315 (35%), Gaps = 51/315 (16%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L+L + + LG+G V + E +
Sbjct 448 NLDLPLDPLWEFPRDRLVLGKPLGEGCFGQV-----------------VRAEAFGMDPSR 490
Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690
Q V +K+L + D L +M + H ++ + GVC + ++ E
Sbjct 491 PDQTSTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECA 550
Query 691 EHGPLDVWLRRER---------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNV 735
G L +LR R G + + A Q+A + YLE++ +H ++
Sbjct 551 AKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDL 610
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGAN 789
RN+L+ +K++D G+ G + + + W+APE L
Sbjct 611 AARNVLVTE-------DDVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRV- 662
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847
+ D W F L EI G +P E + HR+ P +L L +
Sbjct 663 -YTHQSDVWSFEILLWEIFTLGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRE 721
Query 848 CLTYEPTQRPSFRTI 862
C P+QRP+F+ +
Sbjct 722 CWHAAPSQRPTFKQL 736
>sp|Q62270|SRMS_MOUSE Tyrosine-protein kinase Srms OS=Mus musculus
OX=10090 GN=Srms PE=2 SV=2
Length=496
Score = 263 bits (671), Expect = 1e-75, Method: Composition-based stats.
Identities = 100/314 (32%), Positives = 141/314 (45%), Gaps = 28/314 (9%)
Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926
N + D + R LGEG FG+V + +
Sbjct 204 NWKLIQNPLLQPCIPQIPLVQDEWERPRSEFVLRRKLGEGFFGEVWEGLWLGS-----IP 258
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VAVK +K + +EI+ L++L HE +I+ C + + +V E + G+L
Sbjct 259 VAVKVIK--SADMKLADLTKEIEALKSLRHERLIRLHAICSLG--EPVYIVTELMGKGNL 314
Query 987 RDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
+ YL ++ L LL FA Q+ EGM+YL + +HRDLAARNVL+ +D K+ DFG
Sbjct 315 QVYLGSSEGKALSLPHLLGFACQVAEGMSYLEERRVVHRDLAARNVLVGDDLTCKVADFG 374
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
LA+ + + + Y PV W APE F SDVWSFG+ LYE+ T+
Sbjct 375 LARLLKD--DVYSPSSGSKIPVKWTAPEAANYRVFSQKSDVWSFGILLYEVFTYGQ---- 428
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163
MT + + RG RLPRP CP EVY LM CW+ RPTF
Sbjct 429 ----------CPYEGMTNHETLQQISRGYRLPRPAVCPAEVYVLMVECWKGSPEERPTFA 478
Query 1164 NLIPILKTVHEKYQ 1177
L L ++ +
Sbjct 479 ILREKLNAINRRLH 492
Score = 261 bits (666), Expect = 5e-75, Method: Composition-based stats.
Identities = 92/453 (20%), Positives = 151/453 (33%), Gaps = 81/453 (18%)
Query 433 YLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQ 489
YL P S + + Q L G +LI S S L+V
Sbjct 110 YLAKATPEP---PSDQPWYFSGISRAQAQQLLLSPANAPGAFLIRPSESSIGGYSLSVRA 166
Query 490 RSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRR 549
+++ + I + G+ FPS+ L A + + L +
Sbjct 167 QAKVC---------HYRICMAPSGSLYLQEGQLFPSLDALLAYYKTNWKLIQN---PLLQ 214
Query 550 CCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLR 609
C+PQ + + E LG+G V+EG
Sbjct 215 PCIPQIPLVQDE--------------------WERPRSEFVLRRKLGEGFFGEVWEGLWL 254
Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTH 669
+ V +KV+ + +A + + + H
Sbjct 255 GS-------------------------IPVAVKVIKSADMKLA-DLTKEIEALKSLRHER 288
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENK 728
L +H +C G +VTE + G L V+L G + + + A Q+A +SYLE +
Sbjct 289 LIRLHAICSLGEPVYIVTELMGKGNLQVYLGSSEGKALSLPHLLGFACQVAEGMSYLEER 348
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-----EERVERIPWLAPEC 783
+VH ++ RN+L+ G K++D G+ + W APE
Sbjct 349 RVVHRDLAARNVLV-------GDDLTCKVADFGLARLLKDDVYSPSSGSKIPVKWTAPEA 401
Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QL 841
S D W FG L E+ G+ P + + E R +RLP P CP ++
Sbjct 402 A--NYRVFSQKSDVWSFGILLYEVFTYGQCPYEGMTNHETLQQISRGYRLPRPAVCPAEV 459
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
L +C P +RP+F + L +
Sbjct 460 YVLMVECWKGSPEERPTFAILREKLNAINRRLH 492
>sp|Q9UF33|EPHA6_HUMAN Ephrin type-A receptor 6 OS=Homo sapiens
OX=9606 GN=EPHA6 PE=1 SV=3
Length=1036
Score = 275 bits (703), Expect = 1e-75, Method: Composition-based stats.
Identities = 86/363 (24%), Positives = 151/363 (42%), Gaps = 57/363 (16%)
Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911
E +R + ++ + D + ++ R +G G FG+V
Sbjct 586 EEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEV 645
Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
T VA+K LK + R + +E I+ H +II+ +G +
Sbjct 646 CSGRLK-TPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSF 704
Query 972 ----------------------------------------KSLQLVMEYVPLGSLRDYLP 991
+ + +V+EY+ GSL +L
Sbjct 705 PAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLR 764
Query 992 RHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
+H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL++ +
Sbjct 765 KHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLE 824
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
+ E G P+ W APE + KF ASD WS+G+ ++E++++ +
Sbjct 825 DDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYGER--------- 875
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+M+ + +E G RLP P CP ++ LM +CW+ E + RP F +++ L
Sbjct 876 -----PYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFL 930
Query 1170 KTV 1172
+
Sbjct 931 DKL 933
Score = 259 bits (662), Expect = 3e-70, Method: Composition-based stats.
Identities = 88/404 (22%), Positives = 136/404 (34%), Gaps = 88/404 (22%)
Query 570 SPRTLNLSQLSFHR----VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
P T L+ H +D I +G G V GRL+ G
Sbjct 608 DPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGK------------ 655
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVR----- 679
+E+ V +K L H D F AS+M Q H ++ + GV +
Sbjct 656 ---------REIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPA 706
Query 680 -------------------------------------GPENIMVTEYVEHGPLDVWLRRE 702
G ++V EY+E+G LD +LR+
Sbjct 707 IGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKH 766
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
GH + + + + +AS + YL + VH ++ RNIL+ ++ K+SD G+
Sbjct 767 DGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVN-------SNLVCKVSDFGL 819
Query 763 GL-------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
A + I W APE + S+A D W +G + E+ GE P
Sbjct 820 SRVLEDDPEAAYTTTGGKIPIRWTAPEAIA--YRKFSSASDAWSYGIVMWEVMSYGERPY 877
Query 816 QSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
S + + +RLP CP L L C E RP F I+ L +L +
Sbjct 878 WEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNP 937
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917
A V + Y + + + Y
Sbjct 938 SALHTLVEDILVMPESPGEVPEYPLFVTVGDW--LDSIKMGQYK 979
>sp|Q91743|FGFR4_XENLA Fibroblast growth factor receptor 4 OS=Xenopus
laevis OX=8355 GN=fgfr4 PE=2 SV=1
Length=828
Score = 271 bits (693), Expect = 1e-75, Method: Composition-based stats.
Identities = 104/329 (32%), Positives = 153/329 (47%), Gaps = 41/329 (12%)
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VA 928
+ + P F + L + LGEG FG+V E VA
Sbjct 465 CAPMLPGVMEVELPLDAKWEFPRDRLVLGKPLGEGCFGQVVRAEGYGIEKDRPEKPVTVA 524
Query 929 VKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
VK LK + + S E+++++ + H++II G C +G L +++EY G+LR
Sbjct 525 VKMLKDNGTDKDLSDLISEMELMKVIGKHKNIINLLGVCTQEG--PLFVIVEYASKGNLR 582
Query 988 DYL-----------------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030
++L P + L+ A Q+ GM YL ++ IHRDLAARNVL
Sbjct 583 EFLRARRPPTPEDAFDITKVPEELLSFKDLVSCAYQVARGMEYLESKRCIHRDLAARNVL 642
Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
+ D ++KI DFGLA+ V +YY+ +G PV W APE L + + + SD+WSFGV
Sbjct 643 VAEDNVMKIADFGLARGV-HDIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDIWSFGVL 701
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
+E+ T L G + L +LL G R+ +P C E+Y LM+
Sbjct 702 TWEIFT--------------LGGSPYPVIPYEELFKLLREGHRMDKPSNCTHELYMLMRE 747
Query 1151 CWETEASFRPTFENLIP---ILKTVHEKY 1176
CW + RPTF+ L IL V E+Y
Sbjct 748 CWHAVPTQRPTFKQLEHLDRILTAVSEEY 776
Score = 236 bits (602), Expect = 1e-63, Method: Composition-based stats.
Identities = 75/350 (21%), Positives = 125/350 (36%), Gaps = 51/350 (15%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
+ L + + + LG+G V +R EG G ++ + P P
Sbjct 474 EVELPLDAKWEFPRDRLVLGKPLGEGCFGQV----VRAEGYG------IEKDRPEKP--- 520
Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690
+ V +K+L + D L LM + H ++ + GVC + ++ EY
Sbjct 521 ----VTVAVKMLKDNGTDKDLSDLISEMELMKVIGKHKNIINLLGVCTQEGPLFVIVEYA 576
Query 691 EHGPLDVWLRRERGHVPMAW---------------KMVVAQQLASALSYLENKNLVHGNV 735
G L +LR R P + A Q+A + YLE+K +H ++
Sbjct 577 SKGNLREFLRARRPPTPEDAFDITKVPEELLSFKDLVSCAYQVARGMEYLESKRCIHRDL 636
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGAN 789
RN+L+A + +K++D G+ G + + + W+APE L
Sbjct 637 AARNVLVAEDNV-------MKIADFGLARGVHDIDYYKKTSNGRLPVKWMAPEALFDRV- 688
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847
+ D W FG EI G +P E + HR+ P +L L +
Sbjct 689 -YTHQSDIWSFGVLTWEIFTLGGSPYPVIPYEELFKLLREGHRMDKPSNCTHELYMLMRE 747
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897
C PTQRP+F+ + L + + P S
Sbjct 748 CWHAVPTQRPTFKQLEHLDRILTAVSEEYLDLSMPFEQYSPSCEDSASTC 797
>sp|Q8H186|PBL1_ARATH Probable serine/threonine-protein kinase
PBL1 OS=Arabidopsis thaliana OX=3702 GN=PBL1 PE=1 SV=1
Length=389
Score = 259 bits (661), Expect = 1e-75, Method: Composition-based stats.
Identities = 83/287 (29%), Positives = 132/287 (46%), Gaps = 19/287 (7%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+GEG FG V D PT +G ++AVK L D HR W EI+ L L H
Sbjct 67 VGEGGFGCVFRGWLDETTLTPTKSSSGLVIAVKRLNPDGFQGHRE-WLTEINYLGQLSHP 125
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------SIGLAQLLLFAQQICEGM 1011
+++K G C + ++ LV E++ GSL ++L + + + A +G+
Sbjct 126 NLVKLIGYCLEDEQR--LLVYEFMHKGSLENHLFANGNKDFKPLSWILRIKVALDAAKGL 183
Query 1012 AYLHAQ--HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
A+LH+ I+RD+ A N+LLD+D K+ DFGLA+ P G + Y V + A
Sbjct 184 AFLHSDPVKVIYRDIKASNILLDSDFNAKLSDFGLARDGPMGEQSY-VSTRVMGTFGYAA 242
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTEL 1127
PE + SDV+SFGV L ELL + + P K L+ A+ +T R + +
Sbjct 243 PEYVSTGHLNARSDVYSFGVVLLELLCGRQALDHNRPAKEQNLVDWARPYLTSRRKVLLI 302
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
++ + + + C E RPT + ++ L + +
Sbjct 303 VDTRLNSQYKPEGAVRLASIAVQCLSFEPKSRPTMDQVVRALVQLQD 349
Score = 241 bits (614), Expect = 3e-69, Method: Composition-based stats.
Identities = 74/337 (22%), Positives = 134/337 (40%), Gaps = 54/337 (16%)
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
G S T+ + ++ + S +G+G V+ G L D
Sbjct 36 TEGEILSSTTVKSFSFNELKLATRNFRSDSVVGEGGFGCVFRGWL--------------D 81
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
E L P + L + +K L+P + + + Q+SH +L + G C+ +
Sbjct 82 ETTLTPTK-SSSGLVIAVKRLNPDGFQGHREWLTEINYLGQLSHPNLVKLIGYCLEDEQR 140
Query 684 IMVTEYVEHGPLDVWLR--RERGHVPMAW--KMVVAQQLASALSYLENK--NLVHGNVCG 737
++V E++ G L+ L + P++W ++ VA A L++L + +++ ++
Sbjct 141 LLVYEFMHKGSLENHLFANGNKDFKPLSWILRIKVALDAAKGLAFLHSDPVKVIYRDIKA 200
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPECLPGGANSL 791
NILL + KLSD G+ + + + APE + G L
Sbjct 201 SNILLD-------SDFNAKLSDFGLARDGPMGEQSYVSTRVMGTFGYAAPEYVSTG--HL 251
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH--------------RLPEPS 837
+ D + FG LLE+ +A +R E+ + RL
Sbjct 252 NARSDVYSFGVVLLELLCGRQALDHNRPAKEQNLVDWARPYLTSRRKVLLIVDTRLNSQY 311
Query 838 CP----QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P +LA++ QCL++EP RP+ ++R L +LQ
Sbjct 312 KPEGAVRLASIAVQCLSFEPKSRPTMDQVVRALVQLQ 348
>sp|O73875|EPB4A_DANRE Ephrin type-B receptor 4a OS=Danio rerio
OX=7955 GN=ephb4a PE=1 SV=3
Length=987
Score = 274 bits (701), Expect = 1e-75, Method: Composition-based stats.
Identities = 82/336 (24%), Positives = 142/336 (42%), Gaps = 22/336 (7%)
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+ + Q +P + ++ + ++ +K
Sbjct 566 IYCIRKQNNYKDP-ELSDKNGQYLMGQGVKVYIDPFTYEDPNEAVREFAKEIDVSCVKIE 624
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G FG+V VA+K LK + R + E I+ H +II
Sbjct 625 EVIGAGEFGEVCRGRLRIPGKKEN-YVAIKTLKGGYTDKQRRDFLAEASIMGQFQHPNII 683
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+G + ++ E++ G+L +L QL+ + I GM YL
Sbjct 684 HLEGIIT--ASCPVMILTEFMENGALDSFLRLNDGQFTPIQLVGMLRGIASGMKYLSEMS 741
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076
Y+HRDLAARN+L++++ + K+ DFGL++ + E Y G P+ W APE +
Sbjct 742 YVHRDLAARNILVNSNLVCKVSDFGLSRFLQENSSDPTYTSSLGGKIPIRWTAPEAIAFR 801
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
KF ASDVWS+G+ ++E+++ + M+ + +E+ RLP
Sbjct 802 KFTCASDVWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIEQDYRLPP 847
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P CP ++ LM +CW+ E + RP F N++ L +
Sbjct 848 PPDCPTYLHQLMLDCWQKERTARPRFANIVSALDKL 883
Score = 261 bits (666), Expect = 4e-71, Method: Composition-based stats.
Identities = 79/337 (23%), Positives = 130/337 (39%), Gaps = 42/337 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + +G G V GRLR+ G +E V +
Sbjct 614 KEIDVSCVKIEEVIGAGEFGEVCRGRLRIPGK---------------------KENYVAI 652
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + D F AS+M Q H ++ + G+ +++TE++E+G LD +LR
Sbjct 653 KTLKGGYTDKQRRDFLAEASIMGQFQHPNIIHLEGIITASCPVMILTEFMENGALDSFLR 712
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G + + + +AS + YL + VH ++ RNIL+ ++ K+SD
Sbjct 713 LNDGQFTPIQLVGMLRGIASGMKYLSEMSYVHRDLAARNILVN-------SNLVCKVSDF 765
Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
G+ +IP W APE + + A D W +G + E+ G
Sbjct 766 GLSRFLQENSSDPTYTSSLGGKIPIRWTAPEAIA--FRKFTCASDVWSYGIVMWEVMSFG 823
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
E P S + + ++ +RLP P L L C E T RP F I+ L +L
Sbjct 824 ERPYWDMSNQDVINAIEQDYRLPPPPDCPTYLHQLMLDCWQKERTARPRFANIVSALDKL 883
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + +T + S P + + L G
Sbjct 884 IRNPASLKITAQEGAGPSHPLLDQRSPLTPSSCGTVG 920
>sp|P43404|ZAP70_MOUSE Tyrosine-protein kinase ZAP-70 OS=Mus musculus
OX=10090 GN=Zap70 PE=1 SV=3
Length=618
Score = 266 bits (680), Expect = 1e-75, Method: Composition-based stats.
Identities = 97/334 (29%), Positives = 153/334 (46%), Gaps = 22/334 (7%)
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899
++ TL S T EP + + T + + + + + L
Sbjct 281 RVDTLNSDGYTPEPARL-ASSTDKPRPMPMDTSVYESPYSDPEELKDKKLFLKRENLLVA 339
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+LG G+FG V Y VA+K LK + +E I+ L + +I
Sbjct 340 DIELGCGNFGSVRQGVYRMRKKQ--IDVAIKVLKQGTEKADKDEMMREAQIMHQLDNPYI 397
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
++ G C+ ++L LVME G L +L + I ++ + Q+ GM YL +
Sbjct 398 VRLIGVCQ---AEALMLVMEMAGGGPLHKFLLGKKEEIPVSNVAELLHQVAMGMKYLEEK 454
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+++HRDLAARNVLL N KI DFGL+KA+ YY R G P+ WYAPEC+ K
Sbjct 455 NFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRK 514
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWS+GVT++E ++ +M + + +++G+R+ P
Sbjct 515 FSSRSDVWSYGVTMWEAFSYGQK--------------PYKKMKGPEVLDFIKQGKRMECP 560
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+CP E+Y LM +CW + RP F + ++
Sbjct 561 PECPPEMYALMSDCWIYKWEDRPDFLTVEQRMRN 594
Score = 240 bits (612), Expect = 1e-66, Method: Composition-based stats.
Identities = 92/499 (18%), Positives = 164/499 (33%), Gaps = 103/499 (21%)
Query 445 MSIRDGIHGPLLEPFVQAKL---RPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLR 501
H L + KL + DG +L+ L++ +
Sbjct 158 HERMPWYHSSLTREEAERKLYSGQQTDGKFLLRPR-KEQGTYALSL---------VYGKT 207
Query 502 LRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL--------- 552
+ + I Q G F ++ +L L+ L+A + L+ C
Sbjct 208 VYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLK---LKADGLIYRLKEVCPNSSASAAVA 264
Query 553 -----------PQPGETSNLIIMRG------------ARASPRTLNLSQLSFHRVDQKEI 589
QP + + G + P ++ S D +E+
Sbjct 265 APTLPAHPSTFTQPQRRVDTLNSDGYTPEPARLASSTDKPRPMPMDTSVYESPYSDPEEL 324
Query 590 TQLS-------------HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
LG G +V +G R R ++
Sbjct 325 KDKKLFLKRENLLVADIELGCGNFGSVRQGV----------------------YRMRKKQ 362
Query 637 LRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+ V +KVL A +M Q+ + ++ + GVC + ++V E GPL
Sbjct 363 IDVAIKVLKQGTEKADKDEMMREAQIMHQLDNPYIVRLIGVC-QAEALMLVMEMAGGGPL 421
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+L ++ +P++ + Q+A + YLE KN VH ++ RN+LL +
Sbjct 422 HKFLLGKKEEIPVSNVAELLHQVAMGMKYLEEKNFVHRDLAARNVLL-------VNRHYA 474
Query 756 KLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
K+SD G+ + + + W APEC+ S+ D W +G T+ E
Sbjct 475 KISDFGLSKALGADDSYYTARSAGKWPLKWYAPECI--NFRKFSSRSDVWSYGVTMWEAF 532
Query 809 FDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
G+ P + E F ++ R+ P P++ L S C Y+ RP F T+ + +
Sbjct 533 SYGQKPYKKMKGPEVLDFIKQGKRMECPPECPPEMYALMSDCWIYKWEDRPDFLTVEQRM 592
Query 867 TRLQPHNLADVLTVNPDSP 885
+
Sbjct 593 RNYYYSLASRAEGPPQCEQ 611
>sp|P46573|PBL10_ARATH Probable serine/threonine-protein kinase
PBL10 OS=Arabidopsis thaliana OX=3702 GN=PBL10 PE=1 SV=2
Length=412
Score = 259 bits (663), Expect = 1e-75, Method: Composition-based stats.
Identities = 83/285 (29%), Positives = 130/285 (46%), Gaps = 18/285 (6%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LGEG FG V D + GTG ++AVK L D G Q W E++ L H
Sbjct 75 LGEGGFGSVFKGWIDEQTLTASKPGTGVVIAVKKLNQD-GWQGHQEWLAEVNYLGQFSHP 133
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMA 1012
+++K G C + + LV E++P GSL ++L R + L A +G+A
Sbjct 134 NLVKLIGYCLEDEHR--LLVYEFMPRGSLENHLFRRGSYFQPLSWTLRLKVALGAAKGLA 191
Query 1013 YLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
+LH I+RD N+LLD++ K+ DFGLAK P G + + V + AP
Sbjct 192 FLHNAETSVIYRDFKTSNILLDSEYNAKLSDFGLAKDGPTGDKSH-VSTRIMGTYGYAAP 250
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTELL 1128
E L SDV+S+GV L E+L+ + ++ P +L+ A+ + R L ++
Sbjct 251 EYLATGHLTTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLLANKRKLFRVI 310
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ + + C+V L C E RP ++ L+ +
Sbjct 311 DNRLQDQYSMEEACKVATLALRCLTFEIKLRPNMNEVVSHLEHIQ 355
Score = 243 bits (621), Expect = 7e-70, Method: Composition-based stats.
Identities = 71/337 (21%), Positives = 137/337 (41%), Gaps = 55/337 (16%)
Query 565 RGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
R ++ NL +F + + S LG+G +V++G +
Sbjct 43 RTEGEILQSPNLKSFTFAELKAATRNFRPDSVLGEGGFGSVFKGWI-------------- 88
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
++ + G + + +K L+ + + + Q SH +L + G C+
Sbjct 89 -DEQTLTASKPGTGVVIAVKKLNQDGWQGHQEWLAEVNYLGQFSHPNLVKLIGYCLEDEH 147
Query 683 NIMVTEYVEHGPLDVWLRRERGHV-PMAW--KMVVAQQLASALSYLEN--KNLVHGNVCG 737
++V E++ G L+ L R + P++W ++ VA A L++L N ++++ +
Sbjct 148 RLLVYEFMPRGSLENHLFRRGSYFQPLSWTLRLKVALGAAKGLAFLHNAETSVIYRDFKT 207
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSL 791
NILL + KLSD G+ + ++ + + APE L G L
Sbjct 208 SNILLD-------SEYNAKLSDFGLAKDGPTGDKSHVSTRIMGTYGYAAPEYLATG--HL 258
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ--------------HRLPEPS 837
+T D + +G LLE+ A ++R P E++ + +RL +
Sbjct 259 TTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLLANKRKLFRVIDNRLQDQY 318
Query 838 C----PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
++ATL +CLT+E RP+ ++ L +Q
Sbjct 319 SMEEACKVATLALRCLTFEIKLRPNMNEVVSHLEHIQ 355
>sp|Q03526|ITK_MOUSE Tyrosine-protein kinase ITK/TSK OS=Mus musculus
OX=10090 GN=Itk PE=1 SV=1
Length=625
Score = 266 bits (680), Expect = 1e-75, Method: Composition-based stats.
Identities = 80/425 (19%), Positives = 154/425 (36%), Gaps = 66/425 (16%)
Query 449 DGIHGPLLEPFVQAKLRP--EDGLYLIHWSTSHPYRLILTVAQRSQAPDGM--QSLRLRK 504
+ + + + L ++G +++ S + P ++V ++ + + +++
Sbjct 244 EWYNKSISRDKAEKLLLDTGKEGAFMVRDSRT-PGTYTVSVFTKAIISENPCIKHYHIKE 302
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
F S+ L Q G LR +
Sbjct 303 ---TNDSPKRYYVAEKYVFDSIPLLIQYHQYNG---GGLVTRLRYP------------VC 344
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
+ +P T L + + E+T + +G G V+ G +
Sbjct 345 SWRQKAPVTAGLRYGKWV-IQPSELTFVQEIGSGQFGLVHLGYWLNKD------------ 391
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+V +K + F E A +M ++SH L ++GVC+
Sbjct 392 -------------KVAIKTIQEGAMS-EEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPIC 437
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+V E++EHG L +LR +RG + + + ++YLE ++H ++ RN L+
Sbjct 438 LVFEFMEHGCLSDYLRSQRGLFAAETLLGMCLDVCEGMAYLEKACVIHRDLAARNCLV-- 495
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWG 799
G + IK+SD G+ L + + W +PE + S+ D W
Sbjct 496 -----GENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFS--FSRYSSKSDVWS 548
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857
FG + E+ +G+ P ++RS SE RL P + + + + C +P RP
Sbjct 549 FGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASCHVYQIMNHCWKEKPEDRP 608
Query 858 SFRTI 862
F +
Sbjct 609 PFSQL 613
Score = 258 bits (658), Expect = 1e-72, Method: Composition-based stats.
Identities = 83/291 (29%), Positives = 132/291 (45%), Gaps = 27/291 (9%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
V L ++++G G FG V L + + VA+K ++ G +
Sbjct 357 RYGKWVIQPSELTFVQEIGSGQFGLVHLGYWLNKDK-----VAIKTIQE--GAMSEEDFI 409
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLF 1003
+E +++ L H +++ G C +Q + LV E++ G L DYL LL
Sbjct 410 EEAEVMMKLSHPKLVQLYGVCLEQA--PICLVFEFMEHGCLSDYLRSQRGLFAAETLLGM 467
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+CEGMAYL IHRDLAARN L+ ++++K+ DFG+ + V + + Y
Sbjct 468 CLDVCEGMAYLEKACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLD--DQYTSSTGTKF 525
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
PV W +PE ++ SDVWSFGV ++E+ + I +
Sbjct 526 PVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGK--------------IPYENRSNSE 571
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ E + G RL +P C VY +M +CW+ + RP F L+ L + E
Sbjct 572 VVEDISTGFRLYKPRLASCHVYQIMNHCWKEKPEDRPPFSQLLSQLAEIAE 622
>sp|Q9SII6|PIX13_ARATH Probable serine/threonine-protein kinase
PIX13 OS=Arabidopsis thaliana OX=3702 GN=PIX13 PE=1 SV=2
Length=414
Score = 259 bits (662), Expect = 2e-75, Method: Composition-based stats.
Identities = 85/283 (30%), Positives = 128/283 (45%), Gaps = 16/283 (6%)
Query 903 LGEGHFGKVSLYCYD---PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LGEG FGKV + P G ++AVK L A+ Q W+ E++ L + H ++
Sbjct 93 LGEGGFGKVFKGWLEDKTPGKQSNGTVIAVKKLNAE-SFQGFEEWQCEVNFLGRVSHPNL 151
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYL 1014
+K G C + E L LV EY+ GSL ++L R + L A +G+A+L
Sbjct 152 VKLLGYCLEGEE--LLLVYEYMQKGSLENHLFRKGSAVQPLSWEIRLKIAIGAAKGLAFL 209
Query 1015 H--AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
H + I+RD A N+LLD KI DFGLAK P + + + + APE
Sbjct 210 HASEKQVIYRDFKASNILLDGSYNAKISDFGLAKLGPSASQSH-ITTRVMGTHGYAAPEY 268
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTELLER 1130
+ Y SDV+ FGV L E+LT + + PT L + ++ R L +++
Sbjct 269 VATGHLYVKSDVYGFGVVLAEILTGLHALDPTRPTGQHNLTEWIKPHLSERRKLRSIMDP 328
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
P K V L C E RP+ + ++ L+ +
Sbjct 329 RLEGKYPFKSAFRVAQLALKCLGPEPKNRPSMKEVVESLELIE 371
Score = 233 bits (593), Expect = 4e-66, Method: Composition-based stats.
Identities = 76/362 (21%), Positives = 135/362 (37%), Gaps = 55/362 (15%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + L+ R + + LG+G V++G L + G G +
Sbjct 71 NLRIFSLAELRASTRNFRSENVLGEGGFGKVFKGWLEDKTPGKQSNGTV----------- 119
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
+ +K L+ + + + +VSH +L + G C+ G E ++V EY++
Sbjct 120 ------IAVKKLNAESFQGFEEWQCEVNFLGRVSHPNLVKLLGYCLEGEELLLVYEYMQK 173
Query 693 GPLDVWLRRERGHV-PMAW--KMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGL 747
G L+ L R+ V P++W ++ +A A L++L K +++ + NILL
Sbjct 174 GSLENHLFRKGSAVQPLSWEIRLKIAIGAAKGLAFLHASEKQVIYRDFKASNILLD---- 229
Query 748 AEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
S K+SD G+ S + + APE + G L D +GFG
Sbjct 230 ---GSYNAKISDFGLAKLGPSASQSHITTRVMGTHGYAAPEYVATG--HLYVKSDVYGFG 284
Query 802 ATLLEICF-----DGEAPLQSRSPSEKEHFYQRQHR-------------LPEPSCPQLAT 843
L EI D P + +E + + R P S ++A
Sbjct 285 VVLAEILTGLHALDPTRPTGQHNLTEWIKPHLSERRKLRSIMDPRLEGKYPFKSAFRVAQ 344
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
L +CL EP RPS + ++ L ++ N + + S +++
Sbjct 345 LALKCLGPEPKNRPSMKEVVESLELIEAANEKPLERRTTRASPSIRQQQGHYRPQQLSSF 404
Query 904 GE 905
Sbjct 405 RP 406
>sp|Q16288|NTRK3_HUMAN NT-3 growth factor receptor OS=Homo sapiens
OX=9606 GN=NTRK3 PE=1 SV=2
Length=839
Score = 271 bits (693), Expect = 2e-75, Method: Composition-based stats.
Identities = 112/348 (32%), Positives = 157/348 (45%), Gaps = 48/348 (14%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914
P I + + N P + +R + R+LGEG FGKV L
Sbjct 497 GPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAE 556
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
CY+ + +VAVKALK D R +++E ++L L HEHI+K+ G C D L
Sbjct 557 CYNLSPTKDKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PL 613
Query 975 QLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQ 1017
+V EY+ G L +L H +GL+Q+L A QI GM YL +Q
Sbjct 614 IMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQ 673
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG-------------DSP 1064
H++HRDLA RN L+ + LVKIGDFG+++ V Y G P
Sbjct 674 HFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLP 733
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+ W PE + KF SDVWSFGV L+E+ T+ Q++ +
Sbjct 734 IRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQ--------------PWFQLSNTEV 779
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
E + +G L RP CP EVY +M CW+ E R + + IL +
Sbjct 780 IECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 827
Score = 258 bits (658), Expect = 7e-71, Method: Composition-based stats.
Identities = 73/323 (23%), Positives = 126/323 (39%), Gaps = 65/323 (20%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ +++I LG+G V+ + + L P +D+ + V +K
Sbjct 533 IKRRDIVLKRELGEGAFGKVF----------------LAECYNLSPTKDK---MLVAVKA 573
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702
L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR
Sbjct 574 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633
Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+G + ++ + +A Q+AS + YL +++ VH ++ RN L+
Sbjct 634 PDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV------ 687
Query 749 EGTSPFIKLSDPGVGLGALSREE--------------------RVERIPWLAPECLPGGA 788
G + +K+ D G+ S + + I W+ PE +
Sbjct 688 -GANLLVKIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIM--Y 744
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846
+T D W FG L EI G+ P S +E + L P ++ +
Sbjct 745 RKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVML 804
Query 847 QCLTYEPTQRPSFRTILRDLTRL 869
C EP QR + + I + L L
Sbjct 805 GCWQREPQQRLNIKEIYKILHAL 827
>sp|Q9C9U5|SIS8_ARATH Probable serine/threonine-protein kinase
SIS8 OS=Arabidopsis thaliana OX=3702 GN=SIS8 PE=1 SV=1
Length=1030
Score = 274 bits (701), Expect = 2e-75, Method: Composition-based stats.
Identities = 77/284 (27%), Positives = 131/284 (46%), Gaps = 32/284 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G +G+V + G VAVK L D + ++ E+ I++ L H +I+
Sbjct 753 RIGLGSYGEVYRGDWH------GTEVAVKKFLDQDLTGEALEEFRSEVRIMKKLRHPNIV 806
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ G +L +V E++P GSL + R + + + L A GM YLH+ +
Sbjct 807 LFMGAVTRP--PNLSIVTEFLPRGSLYRLIHRPNNQLDERRRLRMALDAARGMNYLHSCN 864
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL + N+L+D + +VK+ DFGL++ H Y + W APE L+
Sbjct 865 PMIVHRDLKSPNLLVDKNWVVKVCDFGLSRM---KHSTYLSSKSTAGTAEWMAPEVLRNE 921
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE-RGERLP 1135
DV+S+GV L+EL T + G+M +++ + + RL
Sbjct 922 PADEKCDVYSYGVILWELFT---------------LQQPWGKMNPMQVVGAVGFQHRRLD 966
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
PD + L+ CW+T++ RP+F ++ LK + + G
Sbjct 967 IPDFVDPAIADLISKCWQTDSKLRPSFAEIMASLKRLQKPVTGS 1010
Score = 254 bits (649), Expect = 1e-68, Method: Composition-based stats.
Identities = 75/350 (21%), Positives = 128/350 (37%), Gaps = 45/350 (13%)
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P I + + +S + +EIT +G G+ VY G
Sbjct 714 PNSGGERISDKSIGNESSKSDCDDVSDCEILWEEITVGERIGLGSYGEVYRGDW------ 767
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFV 673
G E+ V K LD + F +M ++ H ++
Sbjct 768 ------------------HGTEVAVK-KFLDQDLTGEALEEFRSEVRIMKKLRHPNIVLF 808
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LV 731
G R P +VTE++ G L + R + ++ +A A ++YL + N +V
Sbjct 809 MGAVTRPPNLSIVTEFLPRGSLYRLIHRPNNQLDERRRLRMALDAARGMNYLHSCNPMIV 868
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGG 787
H ++ N+L+ + + +K+ D G+ LS + W+APE L
Sbjct 869 HRDLKSPNLLVDK-------NWVVKVCDFGLSRMKHSTYLSSKSTAGTAEWMAPEVLRN- 920
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQHRLPEPSCPQLATL 844
D + +G L E+ + P +P + F R+ +P+ P +A L
Sbjct 921 -EPADEKCDVYSYGVILWELFTL-QQPWGKMNPMQVVGAVGFQHRRLDIPDFVDPAIADL 978
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894
S+C + RPSF I+ L RLQ + S +S PT +
Sbjct 979 ISKCWQTDSKLRPSFAEIMASLKRLQKPVTGSNIPRPVPSSSSLPTEHEQ 1028
>sp|Q24488|ROR1_DROME Tyrosine-protein kinase transmembrane receptor
Ror OS=Drosophila melanogaster OX=7227 GN=Ror PE=1 SV=1
Length=685
Score = 267 bits (683), Expect = 2e-75, Method: Composition-based stats.
Identities = 99/301 (33%), Positives = 152/301 (50%), Gaps = 25/301 (8%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
F + ++ + +LGEG FGKV N T VA+KALK + + + +K+EI+
Sbjct 403 NHFTLQDVEFLEELGEGAFGKVYKGQLLQPNKTT-ITVAIKALKENASVKTQQDFKREIE 461
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQLLLF 1003
++ L H++I+ G ++ + ++ EY+ G L ++L S+ + L
Sbjct 462 LISDLKHQNIVCILGVVLNK--EPYCMLFEYMANGDLHEFLISNSPTEGKSLSQLEFLQI 519
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
A QI EGM YL A HY+HRDLAARN L++ +VKI DFGL++ + +YYRV+
Sbjct 520 ALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIY-SSDYYRVQSKSLL 578
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
PV W E + KF SDVWSFGV L+E+ ++ +
Sbjct 579 PVRWMPSESILYGKFTTESDVWSFGVVLWEIYSYGMQ--------------PYYGFSNQE 624
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE-KYQGQAPS 1182
+ L+ + L P+ CP VY LM CW ++ RPTF ++ LKT HE ++ P
Sbjct 625 VINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRLKTWHEGHFKASNPE 684
Query 1183 V 1183
+
Sbjct 685 M 685
Score = 244 bits (624), Expect = 1e-67, Method: Composition-based stats.
Identities = 62/297 (21%), Positives = 111/297 (37%), Gaps = 43/297 (14%)
Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
L + +++ L LG+G VY+G+L +
Sbjct 400 LRINHFTLQDVEFLEELGEGAFGKVYKGQLLQPNK---------------------TTIT 438
Query 639 VVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V +K L + F L+S + H ++ + GV + M+ EY+ +G L
Sbjct 439 VAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHE 498
Query 698 WLRRERGHV--PMAWK--MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
+L ++ + +A Q++ + YL + VH ++ RN L+ +
Sbjct 499 FLISNSPTEGKSLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLV------ 552
Query 754 FIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+SD G+ S + + W+ E + G +T D W FG L EI
Sbjct 553 -VKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPSESILYG--KFTTESDVWSFGVVLWEI 609
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
G P S E + + + L PE + +L +C + +RP+F I
Sbjct 610 YSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDI 666
>sp|Q9FE20|PBS1_ARATH Serine/threonine-protein kinase PBS1 OS=Arabidopsis
thaliana OX=3702 GN=PBS1 PE=1 SV=1
Length=456
Score = 260 bits (664), Expect = 3e-75, Method: Composition-based stats.
Identities = 82/299 (27%), Positives = 134/299 (45%), Gaps = 19/299 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
LGEG FG+V Y D TG++VAVK L + G Q + E+ +L L
Sbjct 84 MNFHPDTFLGEGGFGRV----YKGRLDSTGQVVAVKQLDRN-GLQGNREFLVEVLMLSLL 138
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICE 1009
+H +++ G C D ++ LV E++PLGSL D+L + ++ + A +
Sbjct 139 HHPNLVNLIGYCADGDQR--LLVYEFMPLGSLEDHLHDLPPDKEALDWNMRMKIAAGAAK 196
Query 1010 GMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G+ +LH + I+RD + N+LLD K+ DFGLAK P G + + V
Sbjct 197 GLEFLHDKANPPVIYRDFKSSNILLDEGFHPKLSDFGLAKLGPTGDKSH-VSTRVMGTYG 255
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVLR-L 1124
+ APE + SDV+SFGV EL+T + S P L+ A+ R
Sbjct 256 YCAPEYAMTGQLTVKSDVYSFGVVFLELITGRKAIDSEMPHGEQNLVAWARPLFNDRRKF 315
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV-HEKYQGQAPS 1182
+L + + P + + + C + +A+ RP +++ L + ++ Y
Sbjct 316 IKLADPRLKGRFPTRALYQALAVASMCIQEQAATRPLIADVVTALSYLANQAYDPSKDD 374
Score = 228 bits (580), Expect = 8e-64, Method: Composition-based stats.
Identities = 64/319 (20%), Positives = 107/319 (34%), Gaps = 63/319 (20%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ LG+G VY+GRL G V +K LD +
Sbjct 85 NFHPDTFLGEGGFGRVYKGRLDSTGQ------------------------VVAVKQLDRN 120
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR---ERG 704
F ++S + H +L + G C G + ++V E++ G L+ L ++
Sbjct 121 GLQGNREFLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEFMPLGSLEDHLHDLPPDKE 180
Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
+ +M +A A L +L +K +++ + NILL KLSD G
Sbjct 181 ALDWNMRMKIAAGAAKGLEFLHDKANPPVIYRDFKSSNILLDE-------GFHPKLSDFG 233
Query 762 VG-LGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
+ LG + V + APE G L+ D + FG LE+ +A
Sbjct 234 LAKLGPTGDKSHVSTRVMGTYGYCAPEYAMTG--QLTVKSDVYSFGVVFLELITGRKAID 291
Query 816 QSRSPSEKEHFYQRQH------------------RLPEPSCPQLATLTSQCLTYEPTQRP 857
E+ + R P + Q + S C+ + RP
Sbjct 292 SEMPHGEQNLVAWARPLFNDRRKFIKLADPRLKGRFPTRALYQALAVASMCIQEQAATRP 351
Query 858 SFRTILRDLTRLQPHNLAD 876
++ L+ L
Sbjct 352 LIADVVTALSYLANQAYDP 370
>sp|Q06548|PBL9_ARATH Probable serine/threonine-protein kinase
PBL9 OS=Arabidopsis thaliana OX=3702 GN=PBL9 PE=1 SV=1
Length=410
Score = 258 bits (660), Expect = 3e-75, Method: Composition-based stats.
Identities = 86/285 (30%), Positives = 132/285 (46%), Gaps = 18/285 (6%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LGEG FG V D + GTG ++AVK L D G Q W E++ L H
Sbjct 74 LGEGGFGCVFKGWIDEKSLTASRPGTGLVIAVKKLNQD-GWQGHQEWLAEVNYLGQFSHR 132
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMA 1012
H++K G C + + LV E++P GSL ++L R + L A +G+A
Sbjct 133 HLVKLIGYCLEDEHR--LLVYEFMPRGSLENHLFRRGLYFQPLSWKLRLKVALGAAKGLA 190
Query 1013 YLHAQ--HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
+LH+ I+RD N+LLD++ K+ DFGLAK P G + + V + AP
Sbjct 191 FLHSSETRVIYRDFKTSNILLDSEYNAKLSDFGLAKDGPIGDKSH-VSTRVMGTHGYAAP 249
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTELL 1128
E L SDV+SFGV L ELL+ + ++ P+ L+ A+ + R + ++
Sbjct 250 EYLATGHLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRKIFRVI 309
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ + + C+V L C TE RP ++ L+ +
Sbjct 310 DNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVVSHLEHIQ 354
Score = 237 bits (604), Expect = 1e-67, Method: Composition-based stats.
Identities = 79/349 (23%), Positives = 133/349 (38%), Gaps = 64/349 (18%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRV 610
P P ++ ++ NL SF + + S LG+G V++G +
Sbjct 39 PSPRTEGEIL---------QSPNLKSFSFAELKSATRNFRPDSVLGEGGFGCVFKGWI-- 87
Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670
DE L R G L + +K L+ + + + Q SH HL
Sbjct 88 ------------DEKSLTASRP-GTGLVIAVKKLNQDGWQGHQEWLAEVNYLGQFSHRHL 134
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV-PMAW--KMVVAQQLASALSYLEN 727
+ G C+ ++V E++ G L+ L R + P++W ++ VA A L++L +
Sbjct 135 VKLIGYCLEDEHRLLVYEFMPRGSLENHLFRRGLYFQPLSWKLRLKVALGAAKGLAFLHS 194
Query 728 K--NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWL 779
+++ + NILL + KLSD G+ + + +
Sbjct 195 SETRVIYRDFKTSNILLD-------SEYNAKLSDFGLAKDGPIGDKSHVSTRVMGTHGYA 247
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGE-----APLQSRSPSEKEH--------- 825
APE L G L+T D + FG LLE+ P R+ E
Sbjct 248 APEYLATG--HLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRKI 305
Query 826 FYQRQHRLPEPSC----PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
F +RL + ++ATL+ +CLT E RP+ ++ L +Q
Sbjct 306 FRVIDNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVVSHLEHIQ 354
>sp|Q84M95|PBL28_ARATH Probable serine/threonine-protein kinase
PBL28 OS=Arabidopsis thaliana OX=3702 GN=PBL28 PE=2 SV=1
Length=375
Score = 257 bits (656), Expect = 4e-75, Method: Composition-based stats.
Identities = 82/361 (23%), Positives = 135/361 (37%), Gaps = 27/361 (7%)
Query 825 HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884
+ +R C L ++ +
Sbjct 10 NKRRRSKSYDTDPCTFLFSIIFARWHK------RVYRTAECWQIEDQASQPRKRRFGSSV 63
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRS 942
LG+G FG+V TGE+VA+K + +
Sbjct 64 YTLKEMEEATSSFSDENLLGKGGFGRVYQGTLK-----TGEVVAIKKMDLPTFKKADGER 118
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQ 999
++ E+DIL L H +++ G C D + LV EY+ G+L+D+L I
Sbjct 119 EFRVEVDILSRLDHPNLVSLIGYCADGKHR--FLVYEYMQNGNLQDHLNGIKEAKISWPI 176
Query 1000 LLLFAQQICEGMAYLHAQ-----HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
L A +G+AYLH+ +HRD + NVLLD++ KI DFGLAK +PEG +
Sbjct 177 RLRIALGAAKGLAYLHSSSSVGIPIVHRDFKSTNVLLDSNYNAKISDFGLAKLMPEGKDT 236
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ--SPPTKFLELI 1112
V ++ PE K SD+++FGV L ELLT + P + ++
Sbjct 237 -CVTARVLGTFGYFDPEYTSTGKLTLQSDIYAFGVVLLELLTGRRAVDLTQGPNEQNLVL 295
Query 1113 GIAQGQMTVLRLTELLE-RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ +L ++++ R + L C E+ RP+ + + L+
Sbjct 296 QVRNILNDRKKLRKVIDVELPRNSYSMEAITMFADLASRCIRIESKERPSVMDCVKELQL 355
Query 1172 V 1172
+
Sbjct 356 I 356
Score = 220 bits (561), Expect = 3e-62, Method: Composition-based stats.
Identities = 62/343 (18%), Positives = 119/343 (35%), Gaps = 70/343 (20%)
Query 565 RGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
+ ++ R S + ++ + + LG+G VY+G L+
Sbjct 50 QASQPRKRRFGSSVYTLKEMEEATSSFSDENLLGKGGFGRVYQGTLKTGE---------- 99
Query 623 DEDPLVPGRDRGQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVR 679
V +K +D D F ++S++ H +L + G C
Sbjct 100 ---------------VVAIKKMDLPTFKKADGEREFRVEVDILSRLDHPNLVSLIGYCAD 144
Query 680 GPENIMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKN-----LVHG 733
G +V EY+++G L L + + ++ +A A L+YL + + +VH
Sbjct 145 GKHRFLVYEYMQNGNLQDHLNGIKEAKISWPIRLRIALGAAKGLAYLHSSSSVGIPIVHR 204
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV------ERIPWLAPECLPGG 787
+ N+LL ++ K+SD G+ ++ + PE G
Sbjct 205 DFKSTNVLLD-------SNYNAKISDFGLAKLMPEGKDTCVTARVLGTFGYFDPEYTSTG 257
Query 788 ANSLSTAMDKWGFGATLLEICFDGEA------PLQSRSPSEKEHFYQRQHRLPEPSC--- 838
L+ D + FG LLE+ A P + + + + +L +
Sbjct 258 --KLTLQSDIYAFGVVLLELLTGRRAVDLTQGPNEQNLVLQVRNILNDRKKLRKVIDVEL 315
Query 839 ----------PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
A L S+C+ E +RPS +++L +
Sbjct 316 PRNSYSMEAITMFADLASRCIRIESKERPSVMDCVKELQLIIY 358
>sp|P43403|ZAP70_HUMAN Tyrosine-protein kinase ZAP-70 OS=Homo
sapiens OX=9606 GN=ZAP70 PE=1 SV=1
Length=619
Score = 265 bits (676), Expect = 4e-75, Method: Composition-based stats.
Identities = 100/336 (30%), Positives = 151/336 (45%), Gaps = 23/336 (7%)
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899
++ TL S T EP + S + + + + L
Sbjct 283 RIDTLNSDGYTPEPARITSPDKPRPMP--MDTSVYESPYSDPEELKDKKLFLKRDNLLIA 340
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+LG G+FG V Y VA+K LK +E I+ L + +I
Sbjct 341 DIELGCGNFGSVRQGVYRMRKKQ--IDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYI 398
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
++ G C+ ++L LVME G L +L R I ++ + Q+ GM YL +
Sbjct 399 VRLIGVCQ---AEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEK 455
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+++HRDLAARNVLL N KI DFGL+KA+ YY R G P+ WYAPEC+ K
Sbjct 456 NFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRK 515
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F SDVWS+GVT++E L++ +M + +E+G+R+ P
Sbjct 516 FSSRSDVWSYGVTMWEALSYGQK--------------PYKKMKGPEVMAFIEQGKRMECP 561
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+CP E+Y LM +CW + RP F + ++ +
Sbjct 562 PECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACY 597
Score = 234 bits (598), Expect = 1e-64, Method: Composition-based stats.
Identities = 92/486 (19%), Positives = 161/486 (33%), Gaps = 104/486 (21%)
Query 445 MSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLR 501
H L + KL DG +L+ L++ +
Sbjct 158 HERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPR-KEQGTYALSL---------IYGKT 207
Query 502 LRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLP-------- 553
+ + I Q G F ++ +L L+ L+A + L+ C
Sbjct 208 VYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLK---LKADGLIYCLKEACPNSSASNASG 264
Query 554 --------------QPGETSNLI-----------IMRGARASPRTLNLSQLSFHRVDQKE 588
P + + I + P ++ S D +E
Sbjct 265 AAAPTLPAHPSTLTHPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDTSVYESPYSDPEE 324
Query 589 ITQLS-------------HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
+ LG G +V +G R R +
Sbjct 325 LKDKKLFLKRDNLLIADIELGCGNFGSVRQGV----------------------YRMRKK 362
Query 636 ELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
++ V +KVL A +M Q+ + ++ + GVC + ++V E GP
Sbjct 363 QIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVC-QAEALMLVMEMAGGGP 421
Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
L +L +R +P++ + Q++ + YLE KN VH ++ RN+LL +
Sbjct 422 LHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLL-------VNRHY 474
Query 755 IKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
K+SD G+ + + + W APEC+ S+ D W +G T+ E
Sbjct 475 AKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECI--NFRKFSSRSDVWSYGVTMWEA 532
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
G+ P + E F ++ R+ P P+L L S C Y+ RP F T+ +
Sbjct 533 LSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQR 592
Query 866 LTRLQP 871
+
Sbjct 593 MRACYY 598
>sp|P33497|RYK_AVIR3 Tyrosine-protein kinase transforming protein
RYK OS=Avian retrovirus RPL30 OX=31671 GN=V-RYK PE=2 SV=1
Length=442
Score = 259 bits (661), Expect = 4e-75, Method: Composition-based stats.
Identities = 91/283 (32%), Positives = 136/283 (48%), Gaps = 27/283 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG FG V +GT + VAVK +K D + + E ++ H ++IK
Sbjct 51 LGEGEFGSVMEGRLS-QPEGTPQKVAVKTMKLDNFSHREIEEFLSEAACIKDFDHPNVIK 109
Query 962 YKGCCEDQGEKSL---QLVMEYVPLGSLRDYLPRHSI-------GLAQLLLFAQQICEGM 1011
G C + + + +V+ ++ G L +L R + L LL F I GM
Sbjct 110 LLGVCIELSSQQIPKPMVVLPFMKYGDLHSFLLRSRLEMAPQFVPLQMLLKFMVDIALGM 169
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
YL ++ ++HRDLAARN +L +D V + DFGL+K + G +YYR PV W A E
Sbjct 170 EYLSSRQFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQGRIAKMPVKWIAIE 228
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
L + + SDVW+FGVT++E+ T + + E L G
Sbjct 229 SLADRVYTTKSDVWAFGVTMWEIATRG--------------MTPYPGVQNHEIYEYLFHG 274
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+RL +P+ C E+Y +M +CW E + RPTF L L+ + E
Sbjct 275 QRLKKPENCLDELYDIMSSCWRAEPADRPTFSQLKVHLEKLLE 317
Score = 234 bits (597), Expect = 3e-66, Method: Composition-based stats.
Identities = 69/313 (22%), Positives = 119/313 (38%), Gaps = 50/313 (16%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+L +D+ ++ LG+G +V EGRL + G
Sbjct 33 QKLQDVVIDRNALSLGKVLGEGEFGSVMEGRL---------------------SQPEGTP 71
Query 637 LRVVLKV--LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-----GPENIMVTEY 689
+V +K LD H F A+ + H ++ + GVC+ P+ ++V +
Sbjct 72 QKVAVKTMKLDNFSHREIEEFLSEAACIKDFDHPNVIKLLGVCIELSSQQIPKPMVVLPF 131
Query 690 VEHGPLDVWLRRERGHV-----PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+++G L +L R R + P+ + +A + YL ++ +H ++ RN +L
Sbjct 132 MKYGDLHSFLLRSRLEMAPQFVPLQMLLKFMVDIALGMEYLSSRQFLHRDLAARNCML-- 189
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKW 798
+ ++D G+ S + + W+A E L +T D W
Sbjct 190 -----RDDMTVCVADFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRV--YTTKSDVW 242
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
FG T+ EI G P E + RL PE +L + S C EP R
Sbjct 243 AFGVTMWEIATRGMTPYPGVQNHEIYEYLFHGQRLKKPENCLDELYDIMSSCWRAEPADR 302
Query 857 PSFRTILRDLTRL 869
P+F + L +L
Sbjct 303 PTFSQLKVHLEKL 315
>sp|Q54TM7|DRKD_DICDI Probable serine/threonine-protein kinase
drkD OS=Dictyostelium discoideum OX=44689 GN=drkD PE=2 SV=1
Length=1288
Score = 275 bits (704), Expect = 6e-75, Method: Composition-based stats.
Identities = 85/316 (27%), Positives = 139/316 (44%), Gaps = 33/316 (10%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+ + + + +G G +G+V + G VAV
Sbjct 824 HQFPVPTIPAKIIEVEKPFEWEVPLSEIAIGARIGRGGYGQVFRGSWR------GTEVAV 877
Query 930 KAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
K L + + S ++E+D+L L H +I+ + G C + +V EY+ GSL +
Sbjct 878 KMLFNDNVNLKLISDLRKEVDLLCKLRHPNIVLFMGACTEPSSP--CIVTEYLSRGSLAN 935
Query 989 YLPRHSI--GLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGL 1044
L SI L GM YLH+++ IHRDL N+L+D+ VK+ DFGL
Sbjct 936 ILLDESIEMDWGLRLQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLVDDSWQVKVADFGL 995
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A + + + W APE L E + +DV+S+ + L+ELLT
Sbjct 996 ATV-----KSHTFAKTMCGTTGWVAPEVLAEEGYTEKADVYSYAIVLWELLTRL------ 1044
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
I +++ ++RGERLP P CP + LM CWET+ + RP+F
Sbjct 1045 ---------IPYAGKNTMQVVRSIDRGERLPMPAWCPPKYAALMNRCWETDPTHRPSFPE 1095
Query 1165 LIPILKTVHEKYQGQA 1180
++PI++ + ++Q +
Sbjct 1096 ILPIMEGMISEFQKEK 1111
Score = 235 bits (599), Expect = 8e-62, Method: Composition-based stats.
Identities = 60/296 (20%), Positives = 109/296 (37%), Gaps = 44/296 (15%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
V EI + +G+G V+ G R V +
Sbjct 844 WEVPLSEIAIGARIGRGGYGQVFRGSWRG--------------------------TEVAV 877
Query 642 KVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
K+L D + + + L+ ++ H ++ G C +VTEY+ G L L
Sbjct 878 KMLFNDNVNLKLISDLRKEVDLLCKLRHPNIVLFMGACTEPSSPCIVTEYLSRGSLANIL 937
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKL 757
E + ++ + A ++YL ++N ++H ++ N+L+ S +K+
Sbjct 938 LDESIEMDWGLRLQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLVD-------DSWQVKV 990
Query 758 SDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
+D G+ + W+APE L + D + + L E+ P
Sbjct 991 ADFGLATVKSHTFAKTMCGTTGWVAPEVLAE--EGYTEKADVYSYAIVLWELLTR-LIPY 1047
Query 816 QSRSPSEKEHFYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
++ + R RLP P+ A L ++C +PT RPSF IL + +
Sbjct 1048 AGKNTMQVVRSIDRGERLPMPAWCPPKYAALMNRCWETDPTHRPSFPEILPIMEGM 1103
>sp|Q9H3Y6|SRMS_HUMAN Tyrosine-protein kinase Srms OS=Homo sapiens
OX=9606 GN=SRMS PE=1 SV=1
Length=488
Score = 260 bits (664), Expect = 7e-75, Method: Composition-based stats.
Identities = 91/447 (20%), Positives = 150/447 (34%), Gaps = 79/447 (18%)
Query 439 APPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPD 495
A P + + + Q L E G +LI S S L+V +++
Sbjct 110 ASPETLSD-QPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVC- 167
Query 496 GMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQP 555
+ + + GR FP + EL + + L + C+PQ
Sbjct 168 --------HYRVSMAADGSLYLQKGRLFPGLEELLTYYKANWKLIQN---PLLQPCMPQ- 215
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615
+ E LG+G V+EG
Sbjct 216 -------------------KAPRQDVWERPHSEFALGRKLGEGYFGEVWEGLWLGS---- 252
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675
L V +KV+ ++ + + + + H L +H
Sbjct 253 ---------------------LPVAIKVIKSANMKL-TDLAKEIQTLKGLRHERLIRLHA 290
Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGN 734
VC G +VTE + G L +L G + + + A Q+A +SYLE + +VH +
Sbjct 291 VCSGGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLGFACQVAEGMSYLEEQRVVHRD 350
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-----EERVERIPWLAPECLPGGAN 789
+ RN+L+ K++D G+ + W APE
Sbjct 351 LAARNVLVDDGLA-------CKVADFGLARLLKDDIYSPSSSSKIPVKWTAPEAA--NYR 401
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQ 847
S D W FG L E+ G+ P + + E R +RLP P +CP ++ L +
Sbjct 402 VFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRGYRLPRPAACPAEVYVLMLE 461
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNL 874
C P +RPSF T+ L + +
Sbjct 462 CWRSSPEERPSFATLREKLHAIHRCHP 488
Score = 259 bits (661), Expect = 2e-74, Method: Composition-based stats.
Identities = 101/311 (32%), Positives = 141/311 (45%), Gaps = 28/311 (9%)
Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926
N + +P D R LGEG+FG+V + +
Sbjct 200 NWKLIQNPLLQPCMPQKAPRQDVWERPHSEFALGRKLGEGYFGEVWEGLWLGSLP----- 254
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VA+K +K + +EI L+ L HE +I+ C G + + +V E + G+L
Sbjct 255 VAIKVIK--SANMKLTDLAKEIQTLKGLRHERLIRLHAVCS--GGEPVYIVTELMRKGNL 310
Query 987 RDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
+ +L ++ L LL FA Q+ EGM+YL Q +HRDLAARNVL+D+ K+ DFG
Sbjct 311 QAFLGTPEGRALRLPPLLGFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFG 370
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
LA+ + + + Y PV W APE F SDVWSFGV L+E+ T+
Sbjct 371 LARLLKD--DIYSPSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQ---- 424
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163
MT + + RG RLPRP CP EVY LM CW + RP+F
Sbjct 425 ----------CPYEGMTNHETLQQIMRGYRLPRPAACPAEVYVLMLECWRSSPEERPSFA 474
Query 1164 NLIPILKTVHE 1174
L L +H
Sbjct 475 TLREKLHAIHR 485
>sp|Q9LDZ5|PBL21_ARATH Probable serine/threonine-protein kinase
PBL21 OS=Arabidopsis thaliana OX=3702 GN=PBL21 PE=1 SV=1
Length=381
Score = 256 bits (655), Expect = 7e-75, Method: Composition-based stats.
Identities = 83/296 (28%), Positives = 133/296 (45%), Gaps = 25/296 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG+V D +G++VA+K L D G Q + E+ +L L+H +++
Sbjct 84 LGEGGFGRVYKGRLD-----SGQVVAIKQLNPD-GLQGNREFIVEVLMLSLLHHPNLVTL 137
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLH-- 1015
G C ++ LV EY+P+GSL D+L + + + A G+ YLH
Sbjct 138 IGYCTSGDQR--LLVYEYMPMGSLEDHLFDLESNQEPLSWNTRMKIAVGAARGIEYLHCT 195
Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
I+RDL + N+LLD + K+ DFGLAK P G + V + APE
Sbjct 196 ANPPVIYRDLKSANILLDKEFSPKLSDFGLAKLGPVGDRTH-VSTRVMGTYGYCAPEYAM 254
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQMTVL-RLTELLERGE 1132
K SD++ FGV L EL+T + + L+ ++ + + L++
Sbjct 255 SGKLTVKSDIYCFGVVLLELITGRKAIDLGQKQGEQNLVTWSRPYLKDQKKFGHLVDPSL 314
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV------HEKYQGQAPS 1182
R P +C ++ C EA +RP +++ L+ + HE +PS
Sbjct 315 RGKYPRRCLNYAIAIIAMCLNEEAHYRPFIGDIVVALEYLAAQSRSHEARNVSSPS 370
Score = 235 bits (599), Expect = 2e-67, Method: Composition-based stats.
Identities = 78/353 (22%), Positives = 128/353 (36%), Gaps = 67/353 (19%)
Query 557 ETSNLIIMRGARASPRTLN-LSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGS 613
E+ + I++ G SP +F + + +++ LG+G VY+GRL
Sbjct 43 ESISGILVNGKVNSPIPGGGARSFTFKELAAATRNFREVNLLGEGGFGRVYKGRL----- 97
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
D GQ V +K L+P F ++S + H +L +
Sbjct 98 ------------------DSGQ--VVAIKQLNPDGLQGNREFIVEVLMLSLLHHPNLVTL 137
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYLE---N 727
G C G + ++V EY+ G L+ L E P++W +M +A A + YL N
Sbjct 138 IGYCTSGDQRLLVYEYMPMGSLEDHLFDLESNQEPLSWNTRMKIAVGAARGIEYLHCTAN 197
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERV-----ERIPWLAP 781
+++ ++ NILL + KLSD G+ LG + V + AP
Sbjct 198 PPVIYRDLKSANILLDKEFSP-------KLSDFGLAKLGPVGDRTHVSTRVMGTYGYCAP 250
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-------- 833
E G L+ D + FG LLE+ +A + E+ + L
Sbjct 251 EYAMSG--KLTVKSDIYCFGVVLLELITGRKAIDLGQKQGEQNLVTWSRPYLKDQKKFGH 308
Query 834 ----------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
P + + CL E RP I+ L L + +
Sbjct 309 LVDPSLRGKYPRRCLNYAIAIIAMCLNEEAHYRPFIGDIVVALEYLAAQSRSH 361
>sp|P04629|NTRK1_HUMAN High affinity nerve growth factor receptor
OS=Homo sapiens OX=9606 GN=NTRK1 PE=1 SV=4
Length=796
Score = 268 bits (685), Expect = 8e-75, Method: Composition-based stats.
Identities = 103/312 (33%), Positives = 156/312 (50%), Gaps = 40/312 (13%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
+R + +LGEG FGKV L C++ + +VAVKALK + R +++E
Sbjct 503 HHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALK-EASESARQDFQREA 561
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--------------- 993
++L L H+HI+++ G C + + L +V EY+ G L +L H
Sbjct 562 ELLTMLQHQHIVRFFGVCTEG--RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAP 619
Query 994 -SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
+GL QLL A Q+ GM YL H++HRDLA RN L+ +VKIGDFG+++ +
Sbjct 620 GPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIY-ST 678
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
+YYRV P+ W PE + KF SDVWSFGV L+E+ T+
Sbjct 679 DYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQ------------ 726
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
Q++ + + +G L RP CP EVY +M+ CW+ E R + +++ L+ +
Sbjct 727 --PWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQAL 784
Query 1173 HEKYQGQAPSVF 1184
QAP V+
Sbjct 785 -----AQAPPVY 791
Score = 262 bits (670), Expect = 9e-73, Method: Composition-based stats.
Identities = 78/345 (23%), Positives = 129/345 (37%), Gaps = 52/345 (15%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
P E + +P+ S H + +++I LG+G V+
Sbjct 477 SPTEGKGSGLQGHIIENPQY--FSDACVHHIKRRDIVLKWELGEGAFGKVF--------- 525
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
+ + L+P +D+ + V +K L + F A L++ + H H+
Sbjct 526 -------LAECHNLLPEQDK---MLVAVKALKEASESARQDFQREAELLTMLQHQHIVRF 575
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRE--------------RGHVPMAWKMVVAQQLA 719
GVC G +MV EY+ HG L+ +LR G + + + VA Q+A
Sbjct 576 FGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVA 635
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE------RV 773
+ + YL + VH ++ RN L+ G +K+ D G+ S + +
Sbjct 636 AGMVYLAGLHFVHRDLATRNCLV-------GQGLVVKIGDFGMSRDIYSTDYYRVGGRTM 688
Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833
I W+ PE + +T D W FG L EI G+ P S +E + L
Sbjct 689 LPIRWMPPESIL--YRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGREL 746
Query 834 --PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
P P++ + C EP QR S + + L L
Sbjct 747 ERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVY 791
>sp|P42679|MATK_HUMAN Megakaryocyte-associated tyrosine-protein
kinase OS=Homo sapiens OX=9606 GN=MATK PE=1 SV=1
Length=507
Score = 260 bits (665), Expect = 1e-74, Method: Composition-based stats.
Identities = 111/370 (30%), Positives = 167/370 (45%), Gaps = 46/370 (12%)
Query 821 SEKEHFY--QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ H+ R L L + T+L
Sbjct 164 RDVIHYRVLHRDGHLTIDEAVFFCNLMDM-------VEHYSKDKGAICTKLVRPKRKHGT 216
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
+ A + + ++L +GEG FG V Y G+ VAVK +K D
Sbjct 217 KSAEEELARAGWLLNLQHLTLGAQIGEGEFGAVLQGEYL------GQKVAVKNIKCDVTA 270
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---I 995
Q + E ++ + HE++++ G QG L +VME+V G+L ++L +
Sbjct 271 Q---AFLDETAVMTKMQHENLVRLLGVILHQG---LYIVMEHVSKGNLVNFLRTRGRALV 324
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
AQLL F+ + EGM YL ++ +HRDLAARN+L+ D + K+ DFGLAKA +G +
Sbjct 325 NTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSS 384
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
R+ PV W APE LK KF SDVWSFGV L+E+ ++ +
Sbjct 385 RL------PVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRA--------------P 424
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+M++ ++E +E+G R+ P+ CP V+ LM +CWE E + RP F L L E
Sbjct 425 YPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLA--REL 482
Query 1176 YQGQAPSVFS 1185
AP+ S
Sbjct 483 RSAGAPASVS 492
Score = 255 bits (652), Expect = 5e-73, Method: Composition-based stats.
Identities = 99/429 (23%), Positives = 169/429 (39%), Gaps = 72/429 (17%)
Query 439 APPRLVMSIRDGIHGPLLEPFVQAKLRP-EDGLYLIHWSTSHPYRLILTVAQRSQAPDGM 497
A P+L S+ HG + +L+P EDGL+L+ S HP +L V+
Sbjct 113 ADPKL--SLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVI--- 167
Query 498 QSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGE 557
+ + +DG ++ F ++ ++ G C L R +
Sbjct 168 ------HYRVLHRDGHLTID-EAVFFCNLMDMVEHYSKDK---GAICTKLVRPKRKHGTK 217
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
++ + R ++ + +T + +G+G V +G +
Sbjct 218 SAEEELARAG--------------WLLNLQHLTLGAQIGEGEFGAVLQGEYLGQ------ 257
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
+V +K + A AF + ++M+++ H +L + GV
Sbjct 258 --------------------KVAVKNIKCDVT--AQAFLDETAVMTKMQHENLVRLLGVI 295
Query 678 VRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736
+ +V E+V G L +LR R R V A + + +A + YLE+K LVH ++
Sbjct 296 LHQG-LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLA 354
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-EERVERIPWLAPECLPGGANSLSTAM 795
RNIL++ +A K+SD G+ + + W APE L G ++
Sbjct 355 ARNILVSEDLVA-------KVSDFGLAKAERKGLDSSRLPVKWTAPEALKHG--KFTSKS 405
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEP 853
D W FG L E+ G AP S E ++ +R+ P CP + L S C EP
Sbjct 406 DVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEP 465
Query 854 TQRPSFRTI 862
+RP FR +
Sbjct 466 ARRPPFRKL 474
>sp|P07949|RET_HUMAN Proto-oncogene tyrosine-protein kinase receptor
Ret OS=Homo sapiens OX=9606 GN=RET PE=1 SV=3
Length=1114
Score = 273 bits (699), Expect = 1e-74, Method: Composition-based stats.
Identities = 106/317 (33%), Positives = 147/317 (46%), Gaps = 43/317 (14%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYC-YDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
F ++ L + LGEG FGKV + VAVK LK + P
Sbjct 715 PKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLS 774
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-------------- 992
E ++L+ + H H+IK G C G L L++EY GSLR +L
Sbjct 775 EFNVLKQVNHPHVIKLYGACSQDG--PLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGS 832
Query 993 -----------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
++ + L+ FA QI +GM YL +HRDLAARN+L+ R +KI D
Sbjct 833 RNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISD 892
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGL++ V E Y + R G PV W A E L ++ + SDVWSFGV L+E++T
Sbjct 893 FGLSRDVYEEDSYVK-RSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVT----- 946
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
L G + RL LL+ G R+ RPD C E+Y LM CW+ E RP
Sbjct 947 ---------LGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPV 997
Query 1162 FENLIPILKTVHEKYQG 1178
F ++ L+ + K +
Sbjct 998 FADISKDLEKMMVKRRD 1014
Score = 239 bits (609), Expect = 3e-63, Method: Composition-based stats.
Identities = 77/369 (21%), Positives = 129/369 (35%), Gaps = 68/369 (18%)
Query 547 LRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSF-------HRVDQKEITQLSHLGQGT 599
RR P S+ R +S +F +K + LG+G
Sbjct 676 FRRPAQAFPVSYSSSG-ARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGE 734
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYET 658
V + + R V +K+L +
Sbjct 735 FGKVVKA-------------------TAFHLKGRAGYTTVAVKMLKENASPSELRDLLSE 775
Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-------------- 704
+++ QV+H H+ ++G C + +++ EY ++G L +LR R
Sbjct 776 FNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNS 835
Query 705 ---------HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+ M + A Q++ + YL LVH ++ RNIL+A +
Sbjct 836 SSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE-------GRKM 888
Query 756 KLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
K+SD G+ + V+R + W+A E L + +T D W FG L EI
Sbjct 889 KISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFD--HIYTTQSDVWSFGVLLWEIVT 946
Query 810 DGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
G P P + + HR+ P+ ++ L QC EP +RP F I +DL
Sbjct 947 LGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLE 1006
Query 868 RLQPHNLAD 876
++
Sbjct 1007 KMMVKRRDY 1015
>sp|Q91009|NTRK1_CHICK High affinity nerve growth factor receptor
(Fragment) OS=Gallus gallus OX=9031 GN=NTRK1 PE=1 SV=1
Length=778
Score = 267 bits (683), Expect = 1e-74, Method: Composition-based stats.
Identities = 101/318 (32%), Positives = 156/318 (49%), Gaps = 40/318 (13%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY---CYDPTNDGTGEMVAVKAL 932
+ + + +R + +LGEG FGKV L P + T +VAVKAL
Sbjct 472 NFIENPQYFCNACVHHVQRRDIVLKWELGEGAFGKVFLAECSHLLPEQEKT--LVAVKAL 529
Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992
K + R +++E ++L L HEHI+K+ G C + L +V EY+ G L +L
Sbjct 530 K-EVTENARLDFQREAELLTVLQHEHIVKFYGVCTEGD--PLIMVFEYMKHGDLNRFLRS 586
Query 993 HS----------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036
H + L+ +L A QI GM YL + H++HRDLA RN L+ +D +
Sbjct 587 HGPDAKILDQGQGQPCGQLTLSHMLQIATQIASGMVYLASLHFVHRDLATRNCLVGHDLV 646
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
VKIGDFG+++ + +YYRV P+ W PE + KF SD+WSFGV L+E+ T
Sbjct 647 VKIGDFGMSRDIY-STDYYRVGGRTMLPIRWMPPESILYRKFTTESDIWSFGVVLWEIFT 705
Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156
+ Q++ E + +G L RP CP EVY +M++CW+ E
Sbjct 706 YGKQ--------------PWYQLSNTEAIECITQGRELERPRTCPSEVYDIMQSCWQREP 751
Query 1157 SFRPTFENLIPILKTVHE 1174
R + +++ L+ + +
Sbjct 752 QQR-SIQDIHSRLQALVK 768
Score = 259 bits (662), Expect = 8e-72, Method: Composition-based stats.
Identities = 70/298 (23%), Positives = 114/298 (38%), Gaps = 50/298 (17%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
H V +++I LG+G V+ ++ V +
Sbjct 486 HHVQRRDIVLKWELGEGAFGKVFLAECSHLLPEQ-------------------EKTLVAV 526
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
K L + L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR
Sbjct 527 KALKEVTENARLDFQREAELLTVLQHEHIVKFYGVCTEGDPLIMVFEYMKHGDLNRFLRS 586
Query 702 ER--------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
G + ++ + +A Q+AS + YL + + VH ++ RN L+
Sbjct 587 HGPDAKILDQGQGQPCGQLTLSHMLQIATQIASGMVYLASLHFVHRDLATRNCLV----- 641
Query 748 AEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFG 801
G +K+ D G+ S + + I W+ PE + +T D W FG
Sbjct 642 --GHDLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESIL--YRKFTTESDIWSFG 697
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857
L EI G+ P S +E + L P ++ + C EP QR
Sbjct 698 VVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRTCPSEVYDIMQSCWQREPQQRS 755
>sp|Q06807|TIE2_BOVIN Angiopoietin-1 receptor OS=Bos taurus OX=9913
GN=TEK PE=2 SV=1
Length=1125
Score = 273 bits (698), Expect = 1e-74, Method: Composition-based stats.
Identities = 98/300 (33%), Positives = 143/300 (48%), Gaps = 40/300 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961
+GEG+FG+V DG A+K +K + E+++L L +H +II
Sbjct 831 IGEGNFGQVLKARIK--KDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIIN 888
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFA 1004
G CE +G L L +EY P G+L D+L + ++ QLL FA
Sbjct 889 LLGACEHRG--YLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFA 946
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+ GM YL + +IHRDLAARN+L+ + + KI DFGL++ G E Y + G P
Sbjct 947 ADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSR----GQEVYVKKTMGRLP 1002
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
V W A E L + SDVWS+GV L+E+++ L G MT L
Sbjct 1003 VRWMAIESLNYSVYTTNSDVWSYGVLLWEIVS--------------LGGTPYCGMTCAEL 1048
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
E L +G RL +P C EVY LM+ CW + RP+F ++ L + E+ + +
Sbjct 1049 YEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTL 1108
Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats.
Identities = 72/353 (20%), Positives = 133/353 (38%), Gaps = 58/353 (16%)
Query 557 ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616
+ L + R A+ +P L ++ + +++ +G+G V + R++ +G
Sbjct 798 NSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDV-----IGEGNFGQVLKARIKKDGL--- 849
Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQV-SHTHLAFVH 674
+ +K + + D F ++ ++ H ++ +
Sbjct 850 -------------------RMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLL 890
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLA 719
G C + EY HG L +LR+ R + + A +A
Sbjct 891 GACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVA 950
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA-LSREERVERIP- 777
+ YL K +H ++ RNIL+ G + K++D G+ G + ++ + R+P
Sbjct 951 RGMDYLSQKQFIHRDLAARNILV-------GENYVAKIADFGLSRGQEVYVKKTMGRLPV 1003
Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--P 834
W+A E L + +T D W +G L EI G P + +E + +RL P
Sbjct 1004 RWMAIESL--NYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKP 1061
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
++ L QC +P +RPSF IL L R+ V T +
Sbjct 1062 LNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTY 1114
>sp|Q4H3K6|FGFR_CIOIN Fibroblast growth factor receptor OS=Ciona
intestinalis OX=7719 GN=FGFR PE=2 SV=1
Length=747
Score = 266 bits (681), Expect = 1e-74, Method: Composition-based stats.
Identities = 108/400 (27%), Positives = 158/400 (40%), Gaps = 54/400 (14%)
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
+ FG I + + K RL P S+ EP
Sbjct 290 IYIFGVVCFIILLAFIVYMCNSRYQNK-----DPPRLIPIENPDNIPPMSK--MEEPVML 342
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916
+ L + + + + + EG FG+V
Sbjct 343 FGNEQAW------RRMCLPHADHIEINIQPDLQWELKREDILLHERIDEGFFGQVFRADL 396
Query 917 DPTNDGTGEMV--AVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKS 973
G E V AVK LK+ + E+D ++ + H++I+ G C G
Sbjct 397 IRCAGGRKEKVDAAVKMLKSTRTEKDMLDLLTEMDQMKRVGKHKNIVNLLGVCTQNG--I 454
Query 974 LQLVMEYVPLGSLRDYLPRH---------------------SIGLAQLLLFAQQICEGMA 1012
L LV EY G+LRDYL R+ + L L+ + Q+ GM
Sbjct 455 LWLVTEYAQKGNLRDYLRRNRPSELQYELSTPDSPAPPRDEPLTLRALMSASHQVARGME 514
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
YL + IHRDLAARNVL+ ND ++KI DFGLA+ + ++YYR G P W A E
Sbjct 515 YLSQKKCIHRDLAARNVLVANDFVMKIADFGLARDIR-SNDYYRKETRGHLPYKWMALEA 573
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + F +A+DVWSFG+ L+E+ + L G + L L G+
Sbjct 574 MTDNMFTHATDVWSFGILLWEIFS--------------LGGSPYPGVKTHDLVRFLRNGD 619
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
RL +P E+Y LM++CWE RP F L+ L +
Sbjct 620 RLEQPQFASSELYRLMRDCWEESPRRRPQFRQLVEDLDRM 659
Score = 231 bits (588), Expect = 3e-62, Method: Composition-based stats.
Identities = 73/352 (21%), Positives = 130/352 (37%), Gaps = 70/352 (20%)
Query 547 LRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606
RR CLP A +N+ + +++I + +G V+
Sbjct 349 WRRMCLPH--------------ADHIEINIQPDLQWELKREDILLHERIDEGFFGQVFRA 394
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV 665
L + R +++ +K+L + + + M +V
Sbjct 395 DL------------------IRCAGGRKEKVDAAVKMLKSTRTEKDMLDLLTEMDQMKRV 436
Query 666 -SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-----------------VP 707
H ++ + GVC + +VTEY + G L +LRR R P
Sbjct 437 GKHKNIVNLLGVCTQNGILWLVTEYAQKGNLRDYLRRNRPSELQYELSTPDSPAPPRDEP 496
Query 708 MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+ + ++ + Q+A + YL K +H ++ RN+L+A +K++D G+
Sbjct 497 LTLRALMSASHQVARGMEYLSQKKCIHRDLAARNVLVAN-------DFVMKIADFGLARD 549
Query 766 ALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
S + + W+A E + + A D W FG L EI G +P
Sbjct 550 IRSNDYYRKETRGHLPYKWMALEAMTDNM--FTHATDVWSFGILLWEIFSLGGSPYPGVK 607
Query 820 PSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ F + RL P+ + +L L C P +RP FR ++ DL R+
Sbjct 608 THDLVRFLRNGDRLEQPQFASSELYRLMRDCWEESPRRRPQFRQLVEDLDRM 659
>sp|G3V9H8|RET_RAT Proto-oncogene tyrosine-protein kinase receptor
Ret OS=Rattus norvegicus OX=10116 GN=Ret PE=1 SV=1
Length=1115
Score = 273 bits (698), Expect = 1e-74, Method: Composition-based stats.
Identities = 112/380 (29%), Positives = 162/380 (43%), Gaps = 47/380 (12%)
Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS- 884
F ++ P + + C P Q R ++ + ++V+
Sbjct 656 FCIHRYHKHAHKPPIASAEMTFC---RPAQGFPISYSSSGTRRPSLDSMENQVSVDSFKI 712
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYC-YDPTNDGTGEMVAVKALKADCGPQHRSG 943
P F ++ L + LGEG FGKV + VAVK LK +
Sbjct 713 PEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRD 772
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------------ 991
E ++L+ + H H+IK G C G L L++EY GSLR +L
Sbjct 773 LLSEFNLLKQVNHPHVIKLYGACSQDG--PLLLIVEYAKYGSLRGFLRDSRKIGPAYVSS 830
Query 992 -------------RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
+ + L+ FA QI GM YL +HRDLAARN+L+ R +K
Sbjct 831 GGSRNSSSLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMK 890
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
I DFGL++ V E Y + + G PV W A E L ++ + SDVWSFGV L+E++T
Sbjct 891 ISDFGLSRDVYEEDSYVK-KSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVT-- 947
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
L G + RL LL+ G R+ RPD C E+Y LM CW+ E
Sbjct 948 ------------LGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDK 995
Query 1159 RPTFENLIPILKTVHEKYQG 1178
RP F ++ L+ + K +
Sbjct 996 RPVFADISKDLEKMMVKSRD 1015
Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats.
Identities = 71/336 (21%), Positives = 124/336 (37%), Gaps = 60/336 (18%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+ S + + + +K + LG+G V +
Sbjct 703 NQVSVDSFKIPEDPKWEFPRKNLVLGKTLGEGEFGKVVKA-------------------T 743
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
+ R V +K+L + +L+ QV+H H+ ++G C + ++
Sbjct 744 AFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNLLKQVNHPHVIKLYGACSQDGPLLL 803
Query 686 VTEYVEHGPLDVWLRRERG-----------------------HVPMAWKMVVAQQLASAL 722
+ EY ++G L +LR R + M + A Q++ +
Sbjct 804 IVEYAKYGSLRGFLRDSRKIGPAYVSSGGSRNSSSLDHPDERVLTMGDLISFAWQISRGM 863
Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------I 776
YL LVH ++ RNIL+A +K+SD G+ + V++ +
Sbjct 864 QYLAEMKLVHRDLAARNILVAE-------GRKMKISDFGLSRDVYEEDSYVKKSKGRIPV 916
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--P 834
W+A E L + +T D W FG L EI G P P + + HR+ P
Sbjct 917 KWMAIESLFD--HIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERP 974
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ ++ L QC EP +RP F I +DL ++
Sbjct 975 DNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMM 1010
>sp|Q02763|TIE2_HUMAN Angiopoietin-1 receptor OS=Homo sapiens
OX=9606 GN=TEK PE=1 SV=2
Length=1124
Score = 273 bits (698), Expect = 1e-74, Method: Composition-based stats.
Identities = 98/300 (33%), Positives = 143/300 (48%), Gaps = 40/300 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961
+GEG+FG+V DG A+K +K + E+++L L +H +II
Sbjct 830 IGEGNFGQVLKARIK--KDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIIN 887
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFA 1004
G CE +G L L +EY P G+L D+L + ++ QLL FA
Sbjct 888 LLGACEHRG--YLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFA 945
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+ GM YL + +IHRDLAARN+L+ + + KI DFGL++ G E Y + G P
Sbjct 946 ADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSR----GQEVYVKKTMGRLP 1001
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
V W A E L + SDVWS+GV L+E+++ L G MT L
Sbjct 1002 VRWMAIESLNYSVYTTNSDVWSYGVLLWEIVS--------------LGGTPYCGMTCAEL 1047
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
E L +G RL +P C EVY LM+ CW + RP+F ++ L + E+ + +
Sbjct 1048 YEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTL 1107
Score = 241 bits (615), Expect = 4e-64, Method: Composition-based stats.
Identities = 74/381 (19%), Positives = 138/381 (36%), Gaps = 58/381 (15%)
Query 529 LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKE 588
+ + + R F R + L + R + +P L ++ + ++
Sbjct 769 ILQLKRANVQRRMAQAFQNVREEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWNDIKFQD 828
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-S 647
+ +G+G V + R++ +G + +K + +
Sbjct 829 V-----IGEGNFGQVLKARIKKDGL----------------------RMDAAIKRMKEYA 861
Query 648 HHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER--- 703
D F ++ ++ H ++ + G C + EY HG L +LR+ R
Sbjct 862 SKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLE 921
Query 704 ------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
+ + A +A + YL K +H ++ RNIL+ G
Sbjct 922 TDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILV-------GE 974
Query 752 SPFIKLSDPGVGLGA-LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ K++D G+ G + ++ + R+P W+A E L + +T D W +G L EI
Sbjct 975 NYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESL--NYSVYTTNSDVWSYGVLLWEIV 1032
Query 809 FDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
G P + +E + +RL P ++ L QC +P +RPSF IL L
Sbjct 1033 SLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSL 1092
Query 867 TRLQPHNLADVLTVNPDSPAS 887
R+ V T +
Sbjct 1093 NRMLEERKTYVNTTLYEKFTY 1113
>sp|Q02858|TIE2_MOUSE Angiopoietin-1 receptor OS=Mus musculus
OX=10090 GN=Tek PE=1 SV=2
Length=1122
Score = 273 bits (697), Expect = 2e-74, Method: Composition-based stats.
Identities = 98/300 (33%), Positives = 143/300 (48%), Gaps = 40/300 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961
+GEG+FG+V DG A+K +K + E+++L L +H +II
Sbjct 828 IGEGNFGQVLKARIK--KDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIIN 885
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFA 1004
G CE +G L L +EY P G+L D+L + ++ QLL FA
Sbjct 886 LLGACEHRG--YLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFA 943
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+ GM YL + +IHRDLAARN+L+ + + KI DFGL++ G E Y + G P
Sbjct 944 ADVARGMDYLSQKQFIHRDLAARNILVGENYIAKIADFGLSR----GQEVYVKKTMGRLP 999
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
V W A E L + SDVWS+GV L+E+++ L G MT L
Sbjct 1000 VRWMAIESLNYSVYTTNSDVWSYGVLLWEIVS--------------LGGTPYCGMTCAEL 1045
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
E L +G RL +P C EVY LM+ CW + RP+F ++ L + E+ + +
Sbjct 1046 YEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTL 1105
Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats.
Identities = 72/353 (20%), Positives = 133/353 (38%), Gaps = 58/353 (16%)
Query 557 ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616
+ L + R A+ +P L ++ + +++ +G+G V + R++ +G
Sbjct 795 NSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDV-----IGEGNFGQVLKARIKKDGL--- 846
Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQV-SHTHLAFVH 674
+ +K + + D F ++ ++ H ++ +
Sbjct 847 -------------------RMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLL 887
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLA 719
G C + EY HG L +LR+ R + + A +A
Sbjct 888 GACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVA 947
Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA-LSREERVERIP- 777
+ YL K +H ++ RNIL+ G + K++D G+ G + ++ + R+P
Sbjct 948 RGMDYLSQKQFIHRDLAARNILV-------GENYIAKIADFGLSRGQEVYVKKTMGRLPV 1000
Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--P 834
W+A E L + +T D W +G L EI G P + +E + +RL P
Sbjct 1001 RWMAIESL--NYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKP 1058
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
++ L QC +P +RPSF IL L R+ V T +
Sbjct 1059 LNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTY 1111
>sp|Q8VYG0|LRL13_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE
PROTEIN KINASE-like 1.3 OS=Arabidopsis thaliana
OX=3702 GN=LRK10L-1.3 PE=2 SV=1
Length=686
Score = 264 bits (675), Expect = 2e-74, Method: Composition-based stats.
Identities = 92/371 (25%), Positives = 155/371 (42%), Gaps = 19/371 (5%)
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL-TVNP 882
+R+ + + L+T T Y + P+ TI L P +V
Sbjct 284 IFIRRRKKLATQYTNKGLSTTTPYSSNYTMSNTPTSTTISGSNHSLVPSISNLGNGSVYS 343
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
+ ++LG+G FG V G VAVK L + +
Sbjct 344 GIQVFSYEELEEATENFSKELGDGGFGTVYYGTLK-----DGRAVAVKRL-FERSLKRVE 397
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGL 997
+K EIDIL++L H +++ G C + + L LV EY+ G+L ++L + I
Sbjct 398 QFKNEIDILKSLKHPNLVILYG-CTTRHSRELLLVYEYISNGTLAEHLHGNQAQSRPICW 456
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
L A + ++YLHA IHRD+ N+LLD++ VK+ DFGL++ P +
Sbjct 457 PARLQIAIETASALSYLHASGIIHRDVKTTNILLDSNYQVKVADFGLSRLFPMDQTHIST 516
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQ 1116
G + PE + Y+ SDV+SFGV L EL++ ++ + + L +A
Sbjct 517 APQG--TPGYVDPEYYQCYRLNEKSDVYSFGVVLSELISSKEAVDITRHRHDINLANMAI 574
Query 1117 GQMTVLRLTELLERGE---RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
++ + EL + R P K V L C + E RP+ + ++ +L+ +
Sbjct 575 SKIQNDAVHELADLSLGFARDPSVKKMMSSVAELAFRCLQQERDVRPSMDEIVEVLRVIQ 634
Query 1174 EKYQGQAPSVF 1184
+ + V
Sbjct 635 KDGISDSKDVV 645
Score = 211 bits (538), Expect = 3e-56, Method: Composition-based stats.
Identities = 59/316 (19%), Positives = 112/316 (35%), Gaps = 44/316 (14%)
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
+ S+ +++ LG G VY G L+
Sbjct 344 GIQVFSYEELEEATENFSKELGDGGFGTVYYGTLKDGR---------------------- 381
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHG 693
V +K L F ++ + H +L ++G R E ++V EY+ +G
Sbjct 382 ---AVAVKRLFERSLKRVEQFKNEIDILKSLKHPNLVILYGCTTRHSRELLLVYEYISNG 438
Query 694 PLDVWLRRERGHV-PMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
L L + P+ W ++ +A + ASALSYL ++H +V NILL
Sbjct 439 TLAEHLHGNQAQSRPICWPARLQIAIETASALSYLHASGIIHRDVKTTNILLD------- 491
Query 751 TSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
++ +K++D G+ + + ++ PE L+ D + FG L
Sbjct 492 SNYQVKVADFGLSRLFPMDQTHISTAPQGTPGYVDPEYYQ--CYRLNEKSDVYSFGVVLS 549
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
E+ EA +R + ++ + +LA L S +P+ + ++
Sbjct 550 ELISSKEAVDITRHRHDINLANMAISKIQNDAVHELADL-SLGFARDPSVKKMMSSVAEL 608
Query 866 LTRLQPHNLADVLTVN 881
R +++
Sbjct 609 AFRCLQQERDVRPSMD 624
>sp|Q0WRY5|PBL7_ARATH Probable serine/threonine-protein kinase
PBL7 OS=Arabidopsis thaliana OX=3702 GN=PBL7 PE=1 SV=1
Length=378
Score = 254 bits (650), Expect = 2e-74, Method: Composition-based stats.
Identities = 80/291 (27%), Positives = 133/291 (46%), Gaps = 18/291 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R +K +GEG FG+V Y T + A+K L + G Q + E+ +L L
Sbjct 71 RNFRKECLIGEGGFGRV----YKGYLASTSQTAAIKQLDHN-GLQGNREFLVEVLMLSLL 125
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICE 1009
+H +++ G C D ++ LV EY+PLGSL D+L + + + A +
Sbjct 126 HHPNLVNLIGYCADGDQR--LLVYEYMPLGSLEDHLHDISPGKQPLDWNTRMKIAAGAAK 183
Query 1010 GMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G+ YLH + I+RDL N+LLD+D K+ DFGLAK P G + + V
Sbjct 184 GLEYLHDKTMPPVIYRDLKCSNILLDDDYFPKLSDFGLAKLGPVGDKSH-VSTRVMGTYG 242
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLR-L 1124
+ APE + SDV+SFGV L E++T + S T L+ A+ R
Sbjct 243 YCAPEYAMTGQLTLKSDVYSFGVVLLEIITGRKAIDSSRSTGEQNLVAWARPLFKDRRKF 302
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+++ + + P + + + C + + + RP +++ L + +
Sbjct 303 SQMADPMLQGQYPPRGLYQALAVAAMCVQEQPNLRPLIADVVTALSYLASQ 353
Score = 235 bits (599), Expect = 3e-67, Method: Composition-based stats.
Identities = 73/335 (22%), Positives = 119/335 (36%), Gaps = 66/335 (20%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
+T S+L+ + + +G+G VY+G L
Sbjct 59 QTFTFSELAT---ATRNFRKECLIGEGGFGRVYKGYLA---------------------- 93
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+K LD + F ++S + H +L + G C G + ++V EY+
Sbjct 94 --STSQTAAIKQLDHNGLQGNREFLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEYMP 151
Query 692 HGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745
G L+ L G P+ W +M +A A L YL +K +++ ++ NILL
Sbjct 152 LGSLEDHLHDISPGKQPLDWNTRMKIAAGAAKGLEYLHDKTMPPVIYRDLKCSNILLD-- 209
Query 746 GLAEGTSPFIKLSDPGVG-LGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWG 799
F KLSD G+ LG + + V + APE G L+ D +
Sbjct 210 -----DDYFPKLSDFGLAKLGPVGDKSHVSTRVMGTYGYCAPEYAMTG--QLTLKSDVYS 262
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------------------RLPEPSCPQL 841
FG LLEI +A SRS E+ + + P Q
Sbjct 263 FGVVLLEIITGRKAIDSSRSTGEQNLVAWARPLFKDRRKFSQMADPMLQGQYPPRGLYQA 322
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
+ + C+ +P RP ++ L+ L
Sbjct 323 LAVAAMCVQEQPNLRPLIADVVTALSYLASQKFDP 357
>sp|Q95YM9|FGFR_HALRO Fibroblast growth factor receptor OS=Halocynthia
roretzi OX=7729 GN=FGFR PE=2 SV=1
Length=763
Score = 266 bits (680), Expect = 2e-74, Method: Composition-based stats.
Identities = 105/407 (26%), Positives = 164/407 (40%), Gaps = 64/407 (16%)
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
++ + L + +++ + P P L + P P I
Sbjct 292 IIIYVMCGVLVILFGLAVVLVLYYHCYNGKDP----PMLVRI------ENPDNIPPMTKI 341
Query 863 LRDLTRL------QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916
Q + + + + + L EG FG+V
Sbjct 342 EHPTMLFGNTQAWQRMCMPMQEPFEFNIQLDLQWELQREDITLVERLDEGFFGQVFKADL 401
Query 917 DPTNDGTGEMV--AVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKS 973
N+ E + AVK LK + + E+D ++ + H++II G C G
Sbjct 402 VTCNNTRKEKMVCAVKMLKGNRNEKDVLDLLTEMDQMKRVGKHKNIINLLGVCTQNG--P 459
Query 974 LQLVMEYVPLGSLRDYLPRH----------------------------SIGLAQLLLFAQ 1005
L LV+EY G+LRDYL R+ ++ ++ FA
Sbjct 460 LWLVIEYAAQGNLRDYLRRNRPQNTLCNLVLPSEGRNPDDELPVPHGDTLTQKDIVSFAF 519
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
Q+ G+ +L + IHRDLAARNVL+ + ++KI DFGLA+ + +YYR G P
Sbjct 520 QVARGLEFLAQKKCIHRDLAARNVLVTEELVMKIADFGLARDIR-SCDYYRKHTRGHLPY 578
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
W A E + + F +A+DVWSFGV L+E+ + L G + L
Sbjct 579 KWMALEAMSDNIFTHATDVWSFGVLLWEIFS--------------LAGSPYPGIKTHELV 624
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ L GERL +P E+Y LM++CWE + S RP F L+ L +
Sbjct 625 KFLRSGERLDKPQYASQEMYRLMRDCWEEDPSKRPNFRTLVEDLDRM 671
Score = 226 bits (576), Expect = 1e-60, Method: Composition-based stats.
Identities = 70/335 (21%), Positives = 127/335 (38%), Gaps = 63/335 (19%)
Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
P N+ + +++IT + L +G V++ L +
Sbjct 364 PFEFNIQLDLQWELQREDITLVERLDEGFFGQVFKADL------------------VTCN 405
Query 631 RDRGQELRVVLKVLDPSHHDI-ALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTE 688
R +++ +K+L + ++ L M +V H ++ + GVC + +V E
Sbjct 406 NTRKEKMVCAVKMLKGNRNEKDVLDLLTEMDQMKRVGKHKNIINLLGVCTQNGPLWLVIE 465
Query 689 YVEHGPLDVWLRRERGHVPMAWK--------------------------MVVAQQLASAL 722
Y G L +LRR R + + A Q+A L
Sbjct 466 YAAQGNLRDYLRRNRPQNTLCNLVLPSEGRNPDDELPVPHGDTLTQKDIVSFAFQVARGL 525
Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP- 777
+L K +H ++ RN+L+ + +K++D G+ R+ +P
Sbjct 526 EFLAQKKCIHRDLAARNVLVTEELV-------MKIADFGLARDIRSCDYYRKHTRGHLPY 578
Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--P 834
W+A E + + A D W FG L EI +P E F + RL P
Sbjct 579 KWMALEAMSDNI--FTHATDVWSFGVLLWEIFSLAGSPYPGIKTHELVKFLRSGERLDKP 636
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + ++ L C +P++RP+FRT++ DL R+
Sbjct 637 QYASQEMYRLMRDCWEEDPSKRPNFRTLVEDLDRM 671
>sp|P16056|MET_MOUSE Hepatocyte growth factor receptor OS=Mus
musculus OX=10090 GN=Met PE=1 SV=1
Length=1379
Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats.
Identities = 93/286 (33%), Positives = 142/286 (50%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L + S + E I++ H
Sbjct 1077 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHP 1135
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1136 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1194
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073
++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L
Sbjct 1195 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1253
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV L+EL+T + +T L +G R
Sbjct 1254 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITIYLLQGRR 1299
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +P+ CP +Y +M CW +A RP+F L+ + ++ + G+
Sbjct 1300 LLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISSIFSTFIGE 1345
Score = 233 bits (593), Expect = 6e-61, Method: Composition-based stats.
Identities = 64/328 (20%), Positives = 121/328 (37%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHH 649
+G+G VY G L G+++ +K L+ +
Sbjct 1078 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1116
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1117 EEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1176
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1177 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1229
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1230 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1287
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1288 FDITIYLLQGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISSIFSTFIGEHY 1347
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D +G
Sbjct 1348 VHVNATYVNVKCVAPYPSLLPSQDNIDG 1375
>sp|F4J0D2|PBL36_ARATH Serine/threonine-protein kinase PBL36 OS=Arabidopsis
thaliana OX=3702 GN=PBL36 PE=1 SV=2
Length=476
Score = 258 bits (659), Expect = 3e-74, Method: Composition-based stats.
Identities = 85/282 (30%), Positives = 127/282 (45%), Gaps = 16/282 (6%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LGEG FG V + P GTG VAVK L D G Q W EI+ L L H
Sbjct 132 LGEGGFGCVFKGWIEENGTAPVKPGTGLTVAVKTLNPD-GLQGHKEWLAEINFLGNLVHP 190
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLH 1015
++K G C ++ ++ LV E++P GSL ++L R + + + A +G+A+LH
Sbjct 191 SLVKLVGYCMEEDQR--LLVYEFMPRGSLENHLFRRTLPLPWSVRMKIALGAAKGLAFLH 248
Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+ I+RD N+LLD + K+ DFGLAK P+ + + V + APE
Sbjct 249 EEAEKPVIYRDFKTSNILLDGEYNAKLSDFGLAKDAPDEKKSH-VSTRVMGTYGYAAPEY 307
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQ-MTVLRLTELLER 1130
+ SDV+SFGV L E+LT S +S P L+ + + R LL+
Sbjct 308 VMTGHLTTKSDVYSFGVVLLEILTGRRSVDKSRPNGEQNLVEWVRPHLLDKKRFYRLLDP 367
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
K + + C ++ RP ++ LK +
Sbjct 368 RLEGHYSIKGAQKATQVAAQCLNRDSKARPKMSEVVEALKPL 409
Score = 249 bits (637), Expect = 3e-71, Method: Composition-based stats.
Identities = 70/340 (21%), Positives = 125/340 (37%), Gaps = 51/340 (15%)
Query 559 SNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618
S+ +M G L + + ++ + S LG+G V++G + G+ +
Sbjct 96 SSTPLMSGELKYSSKLRIFMFNDLKLATRNFRPESLLGEGGFGCVFKGWIEENGTAPVKP 155
Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678
G L V +K L+P + + + + H L + G C+
Sbjct 156 ---------------GTGLTVAVKTLNPDGLQGHKEWLAEINFLGNLVHPSLVKLVGYCM 200
Query 679 RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNV 735
+ ++V E++ G L+ L R +P + +M +A A L++L K +++ +
Sbjct 201 EEDQRLLVYEFMPRGSLENHLFRRTLPLPWSVRMKIALGAAKGLAFLHEEAEKPVIYRDF 260
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGAN 789
NILL KLSD G+ A ++ + + APE + G
Sbjct 261 KTSNILLD-------GEYNAKLSDFGLAKDAPDEKKSHVSTRVMGTYGYAAPEYVMTG-- 311
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ------RQHRLPEPSCPQL-- 841
L+T D + FG LLEI + +SR E+ + R P+L
Sbjct 312 HLTTKSDVYSFGVVLLEILTGRRSVDKSRPNGEQNLVEWVRPHLLDKKRFYRLLDPRLEG 371
Query 842 ----------ATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
+ +QCL + RP ++ L L
Sbjct 372 HYSIKGAQKATQVAAQCLNRDSKARPKMSEVVEALKPLPN 411
>sp|O15146|MUSK_HUMAN Muscle, skeletal receptor tyrosine-protein
kinase OS=Homo sapiens OX=9606 GN=MUSK PE=1 SV=1
Length=869
Score = 268 bits (685), Expect = 3e-74, Method: Composition-based stats.
Identities = 87/336 (26%), Positives = 151/336 (45%), Gaps = 43/336 (13%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND-GTGEMVAV 929
N +P + + ++ +RD+GEG FG+V MVAV
Sbjct 549 HPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAV 608
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K LK + ++ +++E ++ + +I+K G C K + L+ EY+ G L ++
Sbjct 609 KMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEF 666
Query 990 LPR-------------------------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDL 1024
L + A+ L A+Q+ GMAYL + ++HRDL
Sbjct 667 LRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDL 726
Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084
A RN L+ + +VKI DFGL++ + +YY+ E+ P+ W PE + ++ SDV
Sbjct 727 ATRNCLVGENMVVKIADFGLSRNIY-SADYYKANENDAIPIRWMPPESIFYNRYTTESDV 785
Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144
W++GV L+E+ ++ M + + G L P+ CP E+
Sbjct 786 WAYGVVLWEIFSYGLQ--------------PYYGMAHEEVIYYVRDGNILSCPENCPVEL 831
Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180
Y+LM+ CW + RP+F ++ IL+ + E+ +G
Sbjct 832 YNLMRLCWSKLPADRPSFTSIHRILERMCERAEGTV 867
Score = 245 bits (625), Expect = 2e-66, Method: Composition-based stats.
Identities = 71/317 (22%), Positives = 127/317 (40%), Gaps = 60/317 (19%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ I + +G+G V++ R +P V +K+L
Sbjct 571 PRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTM-------------------VAVKML 611
Query 645 DPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--- 700
D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+ +LR
Sbjct 612 KEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMS 671
Query 701 ------------------RERGHVPMA--WKMVVAQQLASALSYLENKNLVHGNVCGRNI 740
G P++ ++ +A+Q+A+ ++YL + VH ++ RN
Sbjct 672 PHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNC 731
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLSTA 794
L+ G + +K++D G+ S + I W+ PE + N +T
Sbjct 732 LV-------GENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIF--YNRYTTE 782
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYE 852
D W +G L EI G P + E ++ + + L PE +L L C +
Sbjct 783 SDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKL 842
Query 853 PTQRPSFRTILRDLTRL 869
P RPSF +I R L R+
Sbjct 843 PADRPSFTSIHRILERM 859
>sp|Q7TPS0|KS6A6_MOUSE Ribosomal protein S6 kinase alpha-6 OS=Mus
musculus OX=10090 GN=Rps6ka6 PE=1 SV=2
Length=764
Score = 266 bits (679), Expect = 3e-74, Method: Composition-based stats.
Identities = 113/670 (17%), Positives = 217/670 (32%), Gaps = 113/670 (17%)
Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
+ P T ++ + + + D + L LGQG+ V+ R + P+ G++ L
Sbjct 73 KEVPITQHVKE-GYEKADPAQFDLLKVLGQGSFGKVFLVRKKTG----PDAGQLYAMKVL 127
Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
LKV D + +H + +H + ++
Sbjct 128 RKAS---------LKVRDRVRTKMERDILVEV------NHPFIVKLHYAFQTEGKLYLIL 172
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
+++ G + L +E K +A +LA AL +L +V+ ++ NILL +G
Sbjct 173 DFLRGGDVFTRLSKEVLFTEEDVKFYLA-ELALALDHLHRLGIVYRDLKPENILLDEIG- 230
Query 748 AEGTSPFIKLSDPGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
IKL+D G+ ++ +E++ + ++APE + A+ S + D W +G
Sbjct 231 ------HIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRAH--SQSADWWSYGVL 282
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEP--------- 853
+ E+ G P Q + +E + + +P+ + +L P
Sbjct 283 MFEML-TGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPANRLGSEGV 341
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG------- 906
+ D F + K G
Sbjct 342 EEVKRHAFFASIDWNKLYKREVQPPFRPASGKPDDTFCFDPEFTAKTPKDSPGLPASANA 401
Query 907 -----HFGKVS---LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE------IDILR 952
F V+ Y T + ++ + + + + +E + +
Sbjct 402 HQLFKGFSFVATSIAEEYKITPVTSSNVLPIVQINGNAAQFSEAYELKEDIGIGSYSVCK 461
Query 953 TLYH--EHI---IKYKGCCEDQGEKSLQLVMEY------VPLGSLRD------------- 988
H ++ +K + + ++++M Y + L + D
Sbjct 462 RCIHSASNVEFAVKIIDKNKRDPSEEIEILMRYGQHPNIISLKEVFDDGKYVYLVTDLMK 521
Query 989 -------YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL-LDNDRL---V 1037
L + + I + + LH+Q +HRDL N+L +D +
Sbjct 522 GGELLDRILKKKCFSEQEASNVLYVITKTVECLHSQGVVHRDLKPSNILYMDESAHPDSI 581
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
KI DFG AK + + + APE L + + A D+WS GV LY +L
Sbjct 582 KICDFGFAKQLRGENGLLLT---PCYTANFVAPEVLTQQGYDAACDIWSLGVLLYTMLAG 638
Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157
+ P E I + G D L+ + +
Sbjct 639 YTPFSNGPNDTPEEILLRIGNGRF---------SLSGGIWDNISRGAKDLLSHMLHMDPH 689
Query 1158 FRPTFENLIP 1167
R T E ++
Sbjct 690 QRYTAEQVLK 699
Score = 147 bits (370), Expect = 8e-35, Method: Composition-based stats.
Identities = 45/268 (17%), Positives = 87/268 (32%), Gaps = 24/268 (9%)
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690
+ +K++D + D + E ++ + H ++ + V G +VT+ +
Sbjct 465 HSASNVEFAVKIIDKNKRDPS----EEIEILMRYGQHPNIISLKEVFDDGKYVYLVTDLM 520
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
+ G L + +++ V + + L ++ +VH ++ NIL
Sbjct 521 KGGELLDRILKKKC-FSEQEASNVLYVITKTVECLHSQGVVHRDLKPSNILYMDESAHPD 579
Query 751 TSPFIKLSDPGVGLGALSREERVERIPWL----APECLPGGANSLSTAMDKWGFGATLLE 806
+ IK+ D G + + APE L A D W G L
Sbjct 580 S---IKICDFGFAKQLRGENGLLLTPCYTANFVAPEVLTQ--QGYDAACDIWSLGVLLYT 634
Query 807 ICFDGEAPLQSRSPS--EKEHFYQRQHR------LPEPSCPQLATLTSQCLTYEPTQRPS 858
+ G P + E+ R + + L S L +P QR +
Sbjct 635 MLA-GYTPFSNGPNDTPEEILLRIGNGRFSLSGGIWDNISRGAKDLLSHMLHMDPHQRYT 693
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPA 886
+L+ Q L + + P
Sbjct 694 AEQVLKHPWITQREQLPRHQPNSDEPPQ 721
>sp|Q9LRY1|PBL25_ARATH Probable serine/threonine-protein kinase
PBL25 OS=Arabidopsis thaliana OX=3702 GN=PBL25 PE=2 SV=1
Length=381
Score = 254 bits (650), Expect = 3e-74, Method: Composition-based stats.
Identities = 82/285 (29%), Positives = 131/285 (46%), Gaps = 18/285 (6%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
++ +GEG FG+V Y + ++VAVK L + G Q + + E+ +L L+
Sbjct 64 NFRQECLIGEGGFGRV----YKGKLENPAQVVAVKQLDRN-GLQGQREFLVEVLMLSLLH 118
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEG 1010
H +++ G C D ++ LV EY+PLGSL D+L + + + A +G
Sbjct 119 HRNLVNLIGYCADGDQR--LLVYEYMPLGSLEDHLLDLEPGQKPLDWNTRIKIALGAAKG 176
Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH + I+RDL + N+LLD + + K+ DFGLAK P G + V +
Sbjct 177 IEYLHDEADPPVIYRDLKSSNILLDPEYVAKLSDFGLAKLGPVGDTLH-VSSRVMGTYGY 235
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQG-QMTVLRLT 1125
APE + SDV+SFGV L EL++ + P+ L+ A R
Sbjct 236 CAPEYQRTGYLTNKSDVYSFGVVLLELISGRRVIDTMRPSHEQNLVTWALPIFRDPTRYW 295
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+L + R P+K + + C E + RP ++I L
Sbjct 296 QLADPLLRGDYPEKSLNQAIAVAAMCLHEEPTVRPLMSDVITALS 340
Score = 245 bits (626), Expect = 6e-71, Method: Composition-based stats.
Identities = 74/407 (18%), Positives = 129/407 (32%), Gaps = 65/407 (16%)
Query 531 AALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ--KE 588
+ +L P T+ ++ + A + +F + K
Sbjct 5 SCFSSKVLDNEGSSMPAPYKQPNSPKRTTGEVVAKNANGPSNNMGARIFTFRELATATKN 64
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
Q +G+G VY+G+L V +K LD +
Sbjct 65 FRQECLIGEGGFGRVYKGKLENPAQ------------------------VVAVKQLDRNG 100
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVP 707
F ++S + H +L + G C G + ++V EY+ G L+ L E G P
Sbjct 101 LQGQREFLVEVLMLSLLHHRNLVNLIGYCADGDQRLLVYEYMPLGSLEDHLLDLEPGQKP 160
Query 708 MAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ W ++ +A A + YL ++ +++ ++ NILL +A KLSD G+
Sbjct 161 LDWNTRIKIALGAAKGIEYLHDEADPPVIYRDLKSSNILLDPEYVA-------KLSDFGL 213
Query 763 GLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
+ + + APE G L+ D + FG LLE+
Sbjct 214 AKLGPVGDTLHVSSRVMGTYGYCAPEYQRTGY--LTNKSDVYSFGVVLLELISGRRVIDT 271
Query 817 SRSPSEKEHFYQRQH------RLPEPSCPQLA------------TLTSQCLTYEPTQRPS 858
R E+ R + + P L + + CL EPT RP
Sbjct 272 MRPSHEQNLVTWALPIFRDPTRYWQLADPLLRGDYPEKSLNQAIAVAAMCLHEEPTVRPL 331
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
++ L+ L + + N
Sbjct 332 MSDVITALSFLGASSNSSNTGSNHLQQNRSNKYQDAVQWDSSPRYAN 378
>sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens
OX=9606 GN=PTK2 PE=1 SV=2
Length=1052
Score = 271 bits (692), Expect = 3e-74, Method: Composition-based stats.
Identities = 100/301 (33%), Positives = 148/301 (49%), Gaps = 24/301 (8%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQH 940
P++ + ++ R +GEG FG V Y P N VA+K K
Sbjct 407 YTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALA--VAIKTCKNCTSDSV 464
Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLA 998
R + QE +R H HI+K G E + ++ME LG LR +L ++S+ LA
Sbjct 465 REKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLA 521
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
L+L+A Q+ +AYL ++ ++HRD+AARNVL+ ++ VK+GDFGL++ + + Y
Sbjct 522 SLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKA 579
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
G P+ W APE + +F ASDVW FGV ++E+L H
Sbjct 580 SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ--------------G 625
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
+ + +E GERLP P CP +Y LM CW + S RP F L L T+ E+ +
Sbjct 626 VKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKA 685
Query 1179 Q 1179
Q
Sbjct 686 Q 686
Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats.
Identities = 69/305 (23%), Positives = 124/305 (41%), Gaps = 39/305 (13%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
T + + + ++ I +G+G +V++G +
Sbjct 406 TYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQG---------------------IYMSP 444
Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
L V +K D F + A M Q H H+ + GV P ++ E
Sbjct 445 ENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCT 503
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G L +L+ + + +A ++ A QL++AL+YLE+K VH ++ RN+L++ +
Sbjct 504 LGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS-------S 556
Query 752 SPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+ +KL D G+ I W+APE + ++A D W FG + E
Sbjct 557 NDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWE 614
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
I G P Q ++ + R +P P L +L ++C Y+P++RP F +
Sbjct 615 ILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKA 674
Query 865 DLTRL 869
L+ +
Sbjct 675 QLSTI 679
Score = 38.1 bits (87), Expect = 0.72, Method: Composition-based stats.
Identities = 32/191 (17%), Positives = 67/191 (35%), Gaps = 25/191 (13%)
Query 120 PAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHF 179
P ++ Q + D + + ++Q K +++ + + +E
Sbjct 117 PEEWKYELRIRYLPKGFLNQFTE--DKPTLNFFYQQVKSDYM---LEIADQVDQEIALKL 171
Query 180 KNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFR 239
+ ++ + AL E + K K P+S ++ + R ++ FR
Sbjct 172 GCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTL--RKLIQQTFR 229
Query 240 RFLRDFQPGRLSQQMVMVKYLATLERLAP--RFGTERVP-------VCHLRLLAQAEGEP 290
+F L+++ ++K+ E L+P RF E + + L E
Sbjct 230 QF------ANLNREESILKF---FEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGI 280
Query 291 CYIRDSGVAPT 301
Y+ D G PT
Sbjct 281 SYLTDKGCNPT 291
>sp|P21709|EPHA1_HUMAN Ephrin type-A receptor 1 OS=Homo sapiens
OX=9606 GN=EPHA1 PE=1 SV=4
Length=976
Score = 270 bits (689), Expect = 3e-74, Method: Composition-based stats.
Identities = 90/307 (29%), Positives = 141/307 (46%), Gaps = 20/307 (7%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
L+P+ +L +GEG FG+V + + V
Sbjct 595 WLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDC-KTV 653
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK + +E I+ H HI+ +G + K + ++ E++ G+L
Sbjct 654 AIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKR--KPIMIITEFMENGALD 711
Query 988 DYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L L QL+ Q I GM YL +Y+HRDLAARN+L++ + K+ DFGL
Sbjct 712 AFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLT 771
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + Y + G P+ W APE + F ASDVWSFG+ ++E+L+ D
Sbjct 772 RLLDDFDGTYET-QGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDK----- 825
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
G+M+ + + +E G RLP P CP +Y LMKNCW + + RP F+ L
Sbjct 826 ---------PYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKL 876
Query 1166 IPILKTV 1172
L+ +
Sbjct 877 QAHLEQL 883
Score = 258 bits (658), Expect = 5e-70, Method: Composition-based stats.
Identities = 79/315 (25%), Positives = 127/315 (40%), Gaps = 39/315 (12%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
+D + + +G+G VY G LR+ V
Sbjct 616 TRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCK---------------------TVA 654
Query 641 LKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+K L + F A++M Q SH H+ + GV + +++TE++E+G LD +L
Sbjct 655 IKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFL 714
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R + + + Q +AS ++YL N N VH ++ RNIL+ + + K+SD
Sbjct 715 REREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQ-------NLCCKVSD 767
Query 760 PGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ G + I W APE + +TA D W FG + E+ G+
Sbjct 768 FGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRI--FTTASDVWSFGIVMWEVLSFGDK 825
Query 814 PLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S E + +RLP P CP L L C Y+ +RP F+ + L +L
Sbjct 826 PYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLA 885
Query 872 HNLADVLTVNPDSPA 886
+ + N D
Sbjct 886 NPHSLRTIANFDPRM 900
>sp|Q09YN5|MET_RABIT Hepatocyte growth factor receptor OS=Oryctolagus
cuniculus OX=9986 GN=MET PE=3 SV=1
Length=1382
Score = 273 bits (699), Expect = 4e-74, Method: Composition-based stats.
Identities = 94/286 (33%), Positives = 141/286 (49%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1080 HFSEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073
++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L
Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1256
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV L+EL+T + +T L +G R
Sbjct 1257 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1302
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +P+ CP +Y +M CW +A RP+F L+ + T+ + G+
Sbjct 1303 LLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISTIFSTFIGE 1348
Score = 230 bits (587), Expect = 3e-60, Method: Composition-based stats.
Identities = 64/329 (19%), Positives = 120/329 (36%), Gaps = 42/329 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1081 FSEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1119
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1291 FDITVYLLQGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISTIFSTFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
+ + V L +D +G
Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNVDGT 1379
>sp|P70600|FAK2_RAT Protein-tyrosine kinase 2-beta OS=Rattus norvegicus
OX=10116 GN=Ptk2b PE=1 SV=1
Length=1009
Score = 270 bits (690), Expect = 4e-74, Method: Composition-based stats.
Identities = 97/278 (35%), Positives = 149/278 (54%), Gaps = 22/278 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG+V Y + G VAVK K DC ++ + E I++ L H HI+K
Sbjct 431 LGEGFFGEVYEGVYTN-HKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKL 489
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G E E+ +VME P G L YL R+ S+ + L+L+A QIC+ MAYL + + +
Sbjct 490 IGIIE---EEPTWIVMELYPYGELGHYLERNKNSLKVPTLVLYALQICKAMAYLESINCV 546
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+A RN+L+ + VK+GDFGL++ + E +YY+ P+ W +PE + +F
Sbjct 547 HRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKASVT-RLPIKWMSPESINFRRFTT 604
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
ASDVW F V ++E+L+ + + +LE+G+RLP+P+ C
Sbjct 605 ASDVWMFAVCMWEILSFGKQ--------------PFFWLENKDVIGVLEKGDRLPKPELC 650
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P +Y LM CW+ + S RP F L+ L +++ +
Sbjct 651 PPVLYTLMTRCWDYDPSDRPRFTELVCSLSDIYQMERD 688
Score = 247 bits (631), Expect = 2e-66, Method: Composition-based stats.
Identities = 75/331 (23%), Positives = 132/331 (40%), Gaps = 39/331 (12%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
A TL + V ++++ LG+G VYEG
Sbjct 403 AEIPDETLRRPGGPQYGVAREDVVLNRILGEGFFGEVYEG-------------------- 442
Query 627 LVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
V +G+++ V +K D F A +M + H H+ + G+ + +
Sbjct 443 -VYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWI 500
Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
V E +G L +L R + + + ++ A Q+ A++YLE+ N VH ++ RNIL+A
Sbjct 501 VMELYPYGELGHYLERNKNSLKVPTLVLYALQICKAMAYLESINCVHRDIAVRNILVA-- 558
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGF 800
+ +KL D G+ + I W++PE + +TA D W F
Sbjct 559 -----SPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESI--NFRRFTTASDVWMF 611
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPS 858
+ EI G+ P + ++ RLP+P P L TL ++C Y+P+ RP
Sbjct 612 AVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDYDPSDRPR 671
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
F ++ L+ + + ++ P
Sbjct 672 FTELVCSLSDIYQMERDIAIEQERNARYRPP 702
>sp|Q5UQG7|YR818_MIMIV Putative serine/threonine-protein kinase/receptor
R818 OS=Acanthamoeba polyphaga mimivirus OX=212035
GN=MIMI_R818 PE=3 SV=1
Length=1651
Score = 274 bits (701), Expect = 4e-74, Method: Composition-based stats.
Identities = 75/286 (26%), Positives = 124/286 (43%), Gaps = 31/286 (11%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEI 948
+ + ++ + +G G +G V++ + N VAVK +K + ++ EI
Sbjct 1387 WIINYDDIQIGKQIGVGSYGIVNMGKWKNIN------VAVKKFVKQKIDEKQMLEFRAEI 1440
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008
L L H HII G C + ++ +V E++ GSLR+ + + Q
Sbjct 1441 AFLSQLRHPHIILMIGACLKR--PNICIVTEFMGNGSLRNVIKTTKPEWKLKIKMLYQTA 1498
Query 1009 EGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G+ YLH IHRD+ N+L+D+ VKI DFG A+ E R
Sbjct 1499 LGIGYLHNSDPIIIHRDIKPSNILVDDSMNVKIADFGFARIKEENSVMTR-----CGTPC 1553
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE ++ K+ DV+SFG+ ++E+LT + ++++
Sbjct 1554 WTAPEIIRGEKYTEKVDVFSFGIVMWEVLTCKEPF---------------SGCNFMKVSM 1598
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ G R P CP + LMK CW + RP+ E++I L +
Sbjct 1599 DILEGARPQIPSDCPIDFTKLMKQCWHAKPDKRPSMEDVIMGLNDM 1644
Score = 243 bits (620), Expect = 4e-64, Method: Composition-based stats.
Identities = 79/296 (27%), Positives = 128/296 (43%), Gaps = 24/296 (8%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHR 941
D L + LG G G+V + G VAVK L ++
Sbjct 779 HQRVEDEWEVDFHELDFMESLGSGGSGEVFKAMWK------GTEVAVKKLVNSNITKDAE 832
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLA 998
+KQEI + +L H +++ + ++ +VME++ LGSL D L I
Sbjct 833 RNFKQEIHRMTSLRHPNVVLFMAASTRP--PNMCIVMEFMSLGSLYDLLGNELVTEIPPV 890
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
+ A Q +GM +LH+ +HRDL + N+LLD+ VK+ DFGL K +
Sbjct 891 LRIRIAYQAAKGMHFLHSSDIVHRDLKSLNLLLDSKWNVKVSDFGLTKIKDNNKGKSSTK 950
Query 1059 EDGDSPVFWYAPECLKEYK--FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
ED + W APE L E + Y +DV+SFG+ ++EL+T IG++
Sbjct 951 EDSVCSIQWTAPEVLSEKQDIDYILADVYSFGIIMWELMTRLRP----------YIGLSP 1000
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ V + + L + + + L+ CW + RP+F ++ L T+
Sbjct 1001 AAIAVAVIRDNLRPEIQEEDINLMSSDYVELVNICWHKDTMIRPSFLEIMTKLSTL 1056
Score = 231 bits (589), Expect = 3e-60, Method: Composition-based stats.
Identities = 61/320 (19%), Positives = 119/320 (37%), Gaps = 46/320 (14%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
++N I+ G + L+ + L ++ +I +G G+ V G+ +
Sbjct 1363 STNGILYGGIKQENEYLSSAGLCRWIINYDDIQIGKQIGVGSYGIVNMGKWKN------- 1415
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHG 675
+ V +K L F + +SQ+ H H+ + G
Sbjct 1416 -------------------INVAVKKFVKQKIDEKQMLEFRAEIAFLSQLRHPHIILMIG 1456
Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHG 733
C++ P +VTE++ +G L ++ + K+ + Q A + YL N + ++H
Sbjct 1457 ACLKRPNICIVTEFMGNGSLRNVIKTTKPE--WKLKIKMLYQTALGIGYLHNSDPIIIHR 1514
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE--ERVERIPWLAPECLPGGANSL 791
++ NIL+ S +K++D G R W APE + G
Sbjct 1515 DIKPSNILVD-------DSMNVKIADFGFARIKEENSVMTRCGTPCWTAPEIIRG--EKY 1565
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEK--EHFYQRQHRLPEPSCPQLATLTSQCL 849
+ +D + FG + E+ E P + + + + ++P L QC
Sbjct 1566 TEKVDVFSFGIVMWEVLTCKE-PFSGCNFMKVSMDILEGARPQIPSDCPIDFTKLMKQCW 1624
Query 850 TYEPTQRPSFRTILRDLTRL 869
+P +RPS ++ L +
Sbjct 1625 HAKPDKRPSMEDVIMGLNDM 1644
Score = 217 bits (552), Expect = 7e-56, Method: Composition-based stats.
Identities = 70/352 (20%), Positives = 117/352 (33%), Gaps = 51/352 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
VD E+ + LG G V++ + G E+ V
Sbjct 786 WEVDFHELDFMESLGSGGSGEVFKAMWK------------------------GTEVAVKK 821
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
V D F + M+ + H ++ R P +V E++ G L L
Sbjct 822 LVNSNITKDAERNFKQEIHRMTSLRHPNVVLFMAASTRPPNMCIVMEFMSLGSLYDLLGN 881
Query 702 E-RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
E +P ++ +A Q A + +L + ++VH ++ N+LL +K+SD
Sbjct 882 ELVTEIPPVLRIRIAYQAAKGMHFLHSSDIVHRDLKSLNLLLDSK-------WNVKVSDF 934
Query 761 GVGL-------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ + ++E+ V I W APE L + D + FG + E+
Sbjct 935 GLTKIKDNNKGKSSTKEDSVCSIQWTAPEVLSEKQDIDYILADVYSFGIIMWELMTR-LR 993
Query 814 PLQSRSPSEKEHFYQRQHRLPEP-------SCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
P SP+ R + PE L + C + RPSF I+ L
Sbjct 994 PYIGLSPAAIAVAVIRDNLRPEIQEEDINLMSSDYVELVNICWHKDTMIRPSFLEIMTKL 1053
Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHK----RYLKKIRDLGEGHFGKVSLY 914
+ L + T S S + D + FG +
Sbjct 1054 STLIGGSGITTGTSTSSSNQSSDYIGPNIITRTKNIHNNDETKNSFGSTTYG 1105
>sp|P35546|RET_MOUSE Proto-oncogene tyrosine-protein kinase receptor
Ret OS=Mus musculus OX=10090 GN=Ret PE=1 SV=2
Length=1115
Score = 271 bits (694), Expect = 4e-74, Method: Composition-based stats.
Identities = 105/320 (33%), Positives = 145/320 (45%), Gaps = 43/320 (13%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYC-YDPTNDGTGEMVAVKALKADCGPQHRSG 943
P F ++ L + LGEG FGKV + VAVK LK +
Sbjct 713 PEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRD 772
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------------ 991
E ++L+ + H H+IK G C G L L++EY GSLR +L
Sbjct 773 LLSEFNLLKQVNHPHVIKLYGACSQDG--PLLLIVEYAKYGSLRGFLRDSRKIGPAYVSG 830
Query 992 -------------RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
+ + L+ FA QI GM YL +HRDLAARN+L+ R +K
Sbjct 831 GGSRNSSSLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMK 890
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
I DFGL++ V E Y + + G PV W A E L ++ + SDVWSFGV L+E++T
Sbjct 891 ISDFGLSRDVYEEDSYVK-KSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVT-- 947
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
L G + RL LL+ G R+ RPD C E+Y LM CW+ E
Sbjct 948 ------------LGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDK 995
Query 1159 RPTFENLIPILKTVHEKYQG 1178
RP F ++ L+ + K +
Sbjct 996 RPVFADISKDLEKMMVKSRD 1015
Score = 242 bits (617), Expect = 3e-64, Method: Composition-based stats.
Identities = 70/330 (21%), Positives = 122/330 (37%), Gaps = 60/330 (18%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
+ + + +K + LG+G V + +
Sbjct 709 SFKIPEDPKWEFPRKNLVLGKTLGEGEFGKVVKA-------------------TAFRLKG 749
Query 633 RGQELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
R V +K+L + +L+ QV+H H+ ++G C + +++ EY +
Sbjct 750 RAGYTTVAVKMLKENASQSELRDLLSEFNLLKQVNHPHVIKLYGACSQDGPLLLIVEYAK 809
Query 692 HGPLDVWLRRERG-----------------------HVPMAWKMVVAQQLASALSYLENK 728
+G L +LR R + M + A Q++ + YL
Sbjct 810 YGSLRGFLRDSRKIGPAYVSGGGSRNSSSLDHPDERVLTMGDLISFAWQISRGMQYLAEM 869
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPE 782
LVH ++ RNIL+A +K+SD G+ + V++ + W+A E
Sbjct 870 KLVHRDLAARNILVAE-------GRKMKISDFGLSRDVYEEDSYVKKSKGRIPVKWMAIE 922
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQ 840
L + +T D W FG L EI G P P + + HR+ P+ +
Sbjct 923 SLFD--HIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEE 980
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ L QC EP +RP F I +DL ++
Sbjct 981 MYRLMLQCWKQEPDKRPVFADISKDLEKMM 1010
>sp|Q9SY91|PBL15_ARATH Probable serine/threonine-protein kinase
PBL15 OS=Arabidopsis thaliana OX=3702 GN=PBL15 PE=1 SV=1
Length=424
Score = 255 bits (652), Expect = 5e-74, Method: Composition-based stats.
Identities = 86/279 (31%), Positives = 130/279 (47%), Gaps = 13/279 (5%)
Query 903 LGEGHFGKVSLYCYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LGEG FGKV D + VAVK L + HR W E+ L L H +++
Sbjct 105 LGEGGFGKVYKGYVDDYLRQSLKAQPVAVKLLDIEGLQGHRE-WLSEVIFLGQLKHPNLV 163
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLH-- 1015
K G C ++ E+ L+ E++P GSL ++L R S+ A L A +G+A+LH
Sbjct 164 KLIGYCCEEEER--VLIYEFMPRGSLENHLFRRISLSLPWATRLKIAVAAAKGLAFLHDL 221
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
I+RD N+LLD+D K+ DFGLAK PEG + + V + APE +
Sbjct 222 ESPIIYRDFKTSNILLDSDFTAKLSDFGLAKMGPEGSKSH-VTTRVMGTYGYAAPEYVST 280
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMT-VLRLTELLERGER 1133
SDV+S+GV L ELLT +++ S P +I ++ +T RL +++
Sbjct 281 GHLTTKSDVYSYGVVLLELLTGRRATEKSRPKNQQNIIDWSKPYLTSSRRLRCVMDPRLA 340
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
K + L C RP ++ L+++
Sbjct 341 GQYSVKAAKDTALLALQCVSPNPKDRPKMLAVVEALESL 379
Score = 229 bits (583), Expect = 1e-64, Method: Composition-based stats.
Identities = 66/330 (20%), Positives = 119/330 (36%), Gaps = 54/330 (16%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L Q+ ++ + + LG+G VY+G + R
Sbjct 83 DLVDFQMCELKMITQSFSGNYLLGEGGFGKVYKGYV------------------DDYLRQ 124
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
+ V +K+LD + + Q+ H +L + G C E +++ E++
Sbjct 125 SLKAQPVAVKLLDIEGLQGHREWLSEVIFLGQLKHPNLVKLIGYCCEEEERVLIYEFMPR 184
Query 693 GPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLAE 749
G L+ L R +P A ++ +A A L++L +++ + NILL
Sbjct 185 GSLENHLFRRISLSLPWATRLKIAVAAAKGLAFLHDLESPIIYRDFKTSNILLD------ 238
Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+ KLSD G+ + + + APE + G L+T D + +G
Sbjct 239 -SDFTAKLSDFGLAKMGPEGSKSHVTTRVMGTYGYAAPEYVSTG--HLTTKSDVYSYGVV 295
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQ------HRLPEPSCPQL------------ATLT 845
LLE+ A +SR +++ + RL P+L A L
Sbjct 296 LLELLTGRRATEKSRPKNQQNIIDWSKPYLTSSRRLRCVMDPRLAGQYSVKAAKDTALLA 355
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
QC++ P RP ++ L L +
Sbjct 356 LQCVSPNPKDRPKMLAVVEALESLIHYKDM 385
>sp|Q7T6Y2|YR831_MIMIV Putative serine/threonine-protein kinase/receptor
R831 OS=Acanthamoeba polyphaga mimivirus OX=212035
GN=MIMI_R831 PE=3 SV=2
Length=1624
Score = 274 bits (700), Expect = 5e-74, Method: Composition-based stats.
Identities = 76/314 (24%), Positives = 130/314 (41%), Gaps = 33/314 (11%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
+ D S + + + + +G G +G V + + VA
Sbjct 1336 IDYMADIDKEDSFLTSANMCRWIINYDEISIGKQIGLGSYGIVFNGKWKGVD------VA 1389
Query 929 VKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
VK +K ++ E+ L L H +I+ + G C + ++ +V EY+ +G+LR
Sbjct 1390 VKKFVKQKLSETQLLEFRAEMAFLSELKHSNIVTFIGACIKK--PNICIVTEYMRMGNLR 1447
Query 988 DYLPRH--SIGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFG 1043
D L I A L G+ YLH+ + +HRD+ N+L+D VKI DFG
Sbjct 1448 DVLKNPDIKITFANKLKLLYGAAMGIDYLHSSNPMIVHRDIKPANILVDEHFNVKIADFG 1507
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
A+ + W APE ++ K+ +DV+SFGV ++E+LT +
Sbjct 1508 FARIKEDN-----TTMTRCGTPCWTAPEVIRGEKYCEKADVFSFGVVMWEVLTGKEPF-- 1560
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163
+ ++++ + G R P CP E L+K CW +A RPT
Sbjct 1561 -------------AECNFMKVSLDILEGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTMT 1607
Query 1164 NLIPILKTVHEKYQ 1177
++ L + E++
Sbjct 1608 EVVQQLMLITEQFD 1621
Score = 247 bits (631), Expect = 1e-65, Method: Composition-based stats.
Identities = 80/320 (25%), Positives = 134/320 (42%), Gaps = 33/320 (10%)
Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922
L + + + + ++ L+ LG G +G+V +
Sbjct 752 CIFGLLLLTLLIVIIFLLKHRNTTNNDWEIDFSELEIGETLGTGGYGEVYKSIWK----- 806
Query 923 TGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
G VAVK + + +E+ I+ +L H +++ + ++ +VME++
Sbjct 807 -GTEVAVKLISSKHVSKDMERSFFEEVKIMTSLRHPNVVLFMAA--STKSPNMCIVMEFM 863
Query 982 PLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
LGSL D L I A + A Q +GM +LH+ +HRDL + N+LLD+ VK
Sbjct 864 SLGSLYDLLGNELIPEIPYALKIKMAYQASKGMHFLHSSGIVHRDLKSLNLLLDSKWNVK 923
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK--FYYASDVWSFGVTLYELLT 1096
+ DFGL K V + + ++ + W APE L + Y +DV+SFG+ L+ELLT
Sbjct 924 VSDFGLTK-VKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSFGIILWELLT 982
Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC----PCEVYHLMKNCW 1152
+G ++ G R P D+ E L+K CW
Sbjct 983 REQPY--------------KGMTPAAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQCW 1028
Query 1153 ETEASFRPTFENLIPILKTV 1172
++ RPTF ++ L +
Sbjct 1029 HSDTIIRPTFLEIMTRLSNI 1048
Score = 230 bits (586), Expect = 6e-60, Method: Composition-based stats.
Identities = 56/309 (18%), Positives = 107/309 (35%), Gaps = 42/309 (14%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L + + ++ EI+ +G G+ V+ G+ +
Sbjct 1349 LTSANMCRWIINYDEISIGKQIGLGSYGIVFNGKWKG----------------------- 1385
Query 634 GQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+ V +K L F + +S++ H+++ G C++ P +VTEY+
Sbjct 1386 ---VDVAVKKFVKQKLSETQLLEFRAEMAFLSELKHSNIVTFIGACIKKPNICIVTEYMR 1442
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAE 749
G L L+ + A K+ + A + YL + N +VH ++ NIL+
Sbjct 1443 MGNLRDVLKNPDIKITFANKLKLLYGAAMGIDYLHSSNPMIVHRDIKPANILVDE----- 1497
Query 750 GTSPFIKLSDPGVGLGALSRE--ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K++D G R W APE + G D + FG + E+
Sbjct 1498 --HFNVKIADFGFARIKEDNTTMTRCGTPCWTAPEVIRG--EKYCEKADVFSFGVVMWEV 1553
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866
E + + + CP A L +C + +RP+ +++ L
Sbjct 1554 LTGKEPFAECNFMKVSLDILEGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTMTEVVQQL 1613
Query 867 TRLQPHNLA 875
+
Sbjct 1614 MLITEQFDH 1622
Score = 226 bits (575), Expect = 1e-58, Method: Composition-based stats.
Identities = 62/304 (20%), Positives = 110/304 (36%), Gaps = 50/304 (16%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D E+ LG G VY+ + V +
Sbjct 779 WEIDFSELEIGETLGTGGYGEVYKSIWKG--------------------------TEVAV 812
Query 642 KVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
K++ H D+ +F+E +M+ + H ++ + P +V E++ G L L
Sbjct 813 KLISSKHVSKDMERSFFEEVKIMTSLRHPNVVLFMAASTKSPNMCIVMEFMSLGSLYDLL 872
Query 700 RRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
E +P A K+ +A Q + + +L + +VH ++ N+LL +K+S
Sbjct 873 GNELIPEIPYALKIKMAYQASKGMHFLHSSGIVHRDLKSLNLLLDSK-------WNVKVS 925
Query 759 DPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
D G+ + + + I W+APE L D + FG L E+ E
Sbjct 926 DFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSFGIILWELLTR-E 984
Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLA-------TLTSQCLTYEPTQRPSFRTILRD 865
P + +P+ R P S + L QC + RP+F I+
Sbjct 985 QPYKGMTPAAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQCWHSDTIIRPTFLEIMTR 1044
Query 866 LTRL 869
L+ +
Sbjct 1045 LSNI 1048
>sp|Q2QLH6|MET_OTOGA Hepatocyte growth factor receptor OS=Otolemur
garnettii OX=30611 GN=MET PE=3 SV=1
Length=1382
Score = 273 bits (698), Expect = 5e-74, Method: Composition-based stats.
Identities = 90/285 (32%), Positives = 138/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD + VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1198 SKKFVHRDLAARNCMLDENFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348
Score = 231 bits (589), Expect = 1e-60, Method: Composition-based stats.
Identities = 64/328 (20%), Positives = 121/328 (37%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1119
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L + +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------NFTVKVADFGLARDMYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D +G
Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNIDG 1378
>sp|P18106|FER_DROME Tyrosine-protein kinase Fer OS=Drosophila
melanogaster OX=7227 GN=FER PE=1 SV=3
Length=1325
Score = 273 bits (697), Expect = 6e-74, Method: Composition-based stats.
Identities = 88/432 (20%), Positives = 157/432 (36%), Gaps = 80/432 (19%)
Query 447 IRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYR-LILTVAQRSQAPDGMQSLRLRKF 505
+ HG L V +L DG +L+ + + ++L+V + F
Sbjct 957 EEEWFHGVLPREEVV-RLLNNDGDFLVRETIRNEESQIVLSVCWNGH----------KHF 1005
Query 506 PIEQQ-DGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
++ +G F EG F S++EL L P + I+
Sbjct 1006 IVQTTGEGNFRFEG--PPFASIQELIMHQYHSEL----------------PVTVKSGAIL 1047
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
R R + ++ L +G+G +VY+ +L+
Sbjct 1048 RRPVCRER---------WELSNDDVVLLERIGRGNFGDVYKAKLK--------------- 1083
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
+L V +K + D F + ++ Q H ++ + G+CV+
Sbjct 1084 ---------STKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPI 1134
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
++V E V G L +LR+ + +M + + A+ + YLE+KN +H ++ RN L+
Sbjct 1135 MIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVD 1194
Query 744 RLGLAEGTSPFIKLSDPGVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
+K+SD G+ +S + + W APE L G ++ D W
Sbjct 1195 -------LEHSVKISDFGMSREEEEYIVSDGMKQIPVKWTAPEALNFG--KYTSLCDVWS 1245
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ--LATLTSQCLTYEPTQRP 857
+G + EI G+ P + S +R+P P + L QC + RP
Sbjct 1246 YGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRP 1305
Query 858 SFRTILRDLTRL 869
F I + L
Sbjct 1306 HFDEIYNVVDAL 1317
Score = 270 bits (689), Expect = 6e-73, Method: Composition-based stats.
Identities = 92/326 (28%), Positives = 144/326 (44%), Gaps = 25/326 (8%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
+E S + ++ + + + + + +G G+F
Sbjct 1015 FRFEGPPFASIQELIMHQYHSELPVTVKSGAILRRPVCRERWELSNDDVVLLERIGRGNF 1074
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968
G V Y T VAVK + + + + QE IL+ H +I+K G C
Sbjct 1075 GDV----YKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQ 1130
Query 969 QGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYIHRDLAA 1026
+ + + +VME V GSL YL ++S GL + + GM YL +++ IHRDLAA
Sbjct 1131 K--QPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAA 1188
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RN L+D + VKI DFG+++ E EY PV W APE L K+ DVWS
Sbjct 1189 RNCLVDLEHSVKISDFGMSR---EEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWS 1245
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
+G+ ++E+ + D+ MT R E ++ G R+P P P E+Y
Sbjct 1246 YGILMWEIFSKGDT--------------PYSGMTNSRARERIDTGYRMPTPKSTPEEMYR 1291
Query 1147 LMKNCWETEASFRPTFENLIPILKTV 1172
LM CW +A RP F+ + ++ +
Sbjct 1292 LMLQCWAADAESRPHFDEIYNVVDAL 1317
>sp|Q9SFX0|PBL22_ARATH Probable serine/threonine-protein kinase
PBL22 OS=Arabidopsis thaliana OX=3702 GN=PBL22 PE=2 SV=1
Length=381
Score = 253 bits (647), Expect = 7e-74, Method: Composition-based stats.
Identities = 77/286 (27%), Positives = 131/286 (46%), Gaps = 19/286 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FG V D +G++VA+K L D G Q + E+ +L +H +++
Sbjct 81 IGKGGFGSVYKGRLD-----SGQVVAIKQLNPD-GHQGNQEFIVEVCMLSVFHHPNLVTL 134
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLH-- 1015
G C ++ LV EY+P+GSL D+L + + + A G+ YLH
Sbjct 135 IGYCTSGAQR--LLVYEYMPMGSLEDHLFDLEPDQTPLSWYTRMKIAVGAARGIEYLHCK 192
Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+ I+RDL + N+LLD + VK+ DFGLAK P G+ + V + APE
Sbjct 193 ISPSVIYRDLKSANILLDKEFSVKLSDFGLAKVGPVGNRTH-VSTRVMGTYGYCAPEYAM 251
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQM-TVLRLTELLERGE 1132
+ SD++SFGV L EL++ + S P L+ A+ + + L++
Sbjct 252 SGRLTIKSDIYSFGVVLLELISGRKAIDLSKPNGEQYLVAWARPYLKDPKKFGLLVDPLL 311
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
R +C + + C EA+ RP +++ + + + +
Sbjct 312 RGKFSKRCLNYAISITEMCLNDEANHRPKIGDVVVAFEYIASQSKS 357
Score = 239 bits (611), Expect = 6e-69, Method: Composition-based stats.
Identities = 74/350 (21%), Positives = 129/350 (37%), Gaps = 67/350 (19%)
Query 553 PQPGETSNLIIMRGARASPRTLN-LSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLR 609
P+ + + I++ G SP+ +F + K + + +G+G +VY+GRL
Sbjct 36 PRGTGSKSGILVNGKVNSPKPGGGARSFTFKELAAATKNFREGNIIGKGGFGSVYKGRL- 94
Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTH 669
D GQ V +K L+P H F ++S H +
Sbjct 95 ----------------------DSGQ--VVAIKQLNPDGHQGNQEFIVEVCMLSVFHHPN 130
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYLE 726
L + G C G + ++V EY+ G L+ L E P++W +M +A A + YL
Sbjct 131 LVTLIGYCTSGAQRLLVYEYMPMGSLEDHLFDLEPDQTPLSWYTRMKIAVGAARGIEYLH 190
Query 727 ---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIP 777
+ ++++ ++ NILL + +KLSD G+ +
Sbjct 191 CKISPSVIYRDLKSANILLDKE-------FSVKLSDFGLAKVGPVGNRTHVSTRVMGTYG 243
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP- 836
+ APE G L+ D + FG LLE+ +A S+ E+ + L +P
Sbjct 244 YCAPEYAMSG--RLTIKSDIYSFGVVLLELISGRKAIDLSKPNGEQYLVAWARPYLKDPK 301
Query 837 -----------------SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
++T CL E RP ++ +
Sbjct 302 KFGLLVDPLLRGKFSKRCLNYAISITEMCLNDEANHRPKIGDVVVAFEYI 351
>sp|Q2IBC0|MET_RHIFE Hepatocyte growth factor receptor OS=Rhinolophus
ferrumequinum OX=59479 GN=MET PE=3 SV=1
Length=1381
Score = 273 bits (697), Expect = 7e-74, Method: Composition-based stats.
Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V ND AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073
++ ++HRDLAARN +LD + VK+ DFGLA+ V + EYY V + PV W A E L
Sbjct 1197 SKKFVHRDLAARNCMLDENFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESL 1255
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV L+EL+T + +T L +G R
Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1302 LLQPEYCPDHLYEVMLKCWHPKAEQRPSFAELVSRISAIFSAFIGE 1347
Score = 231 bits (589), Expect = 2e-60, Method: Composition-based stats.
Identities = 64/328 (20%), Positives = 121/328 (37%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L +++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L + +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------NFTVKVADFGLARDVYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + QRPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDHLYEVMLKCWHPKAEQRPSFAELVSRISAIFSAFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D +G
Sbjct 1350 VHVNATYVNVKCVAPYPCLLSSQDHVDG 1377
>sp|Q9QVP9|FAK2_MOUSE Protein-tyrosine kinase 2-beta OS=Mus musculus
OX=10090 GN=Ptk2b PE=1 SV=2
Length=1009
Score = 270 bits (689), Expect = 7e-74, Method: Composition-based stats.
Identities = 95/278 (34%), Positives = 148/278 (53%), Gaps = 22/278 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG+V Y + G VAVK K DC ++ + E I++ L H HI+K
Sbjct 431 LGEGFFGEVYEGVYTN-HKGEKINVAVKTCKKDCTQDNKEKFMSEAVIMKNLDHPHIVKL 489
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G E E+ ++ME P G L YL R+ S+ + L+L+ QIC+ MAYL + + +
Sbjct 490 IGIIE---EEPTWIIMELYPYGELGHYLERNKNSLKVPTLVLYTLQICKAMAYLESINCV 546
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+A RN+L+ + VK+GDFGL++ + E +YY+ P+ W +PE + +F
Sbjct 547 HRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKASVT-RLPIKWMSPESINFRRFTT 604
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
ASDVW F V ++E+L+ + + +LE+G+RLP+P+ C
Sbjct 605 ASDVWMFAVCMWEILSFGKQ--------------PFFWLENKDVIGVLEKGDRLPKPELC 650
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P +Y LM CW+ + S RP F L+ L +++ +
Sbjct 651 PPVLYTLMTRCWDYDPSDRPRFTELVCSLSDIYQMEKD 688
Score = 246 bits (627), Expect = 6e-66, Method: Composition-based stats.
Identities = 74/331 (22%), Positives = 131/331 (40%), Gaps = 39/331 (12%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
A TL + V ++E+ LG+G VYEG
Sbjct 403 AEIPDETLRRPGGPQYGVAREEVVLNRILGEGFFGEVYEG-------------------- 442
Query 627 LVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
V +G+++ V +K D F A +M + H H+ + G+ + +
Sbjct 443 -VYTNHKGEKINVAVKTCKKDCTQDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWI 500
Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
+ E +G L +L R + + + ++ Q+ A++YLE+ N VH ++ RNIL+A
Sbjct 501 IMELYPYGELGHYLERNKNSLKVPTLVLYTLQICKAMAYLESINCVHRDIAVRNILVA-- 558
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGF 800
+ +KL D G+ + I W++PE + +TA D W F
Sbjct 559 -----SPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESI--NFRRFTTASDVWMF 611
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPS 858
+ EI G+ P + ++ RLP+P P L TL ++C Y+P+ RP
Sbjct 612 AVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDYDPSDRPR 671
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
F ++ L+ + + ++ P
Sbjct 672 FTELVCSLSDIYQMEKDIAIEQERNARYRPP 702
>sp|Q9VBW3|CAD96_DROME Tyrosine kinase receptor Cad96Ca OS=Drosophila
melanogaster OX=7227 GN=Cad96Ca PE=2 SV=2
Length=773
Score = 265 bits (677), Expect = 7e-74, Method: Composition-based stats.
Identities = 91/301 (30%), Positives = 141/301 (47%), Gaps = 33/301 (11%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG-EMVAVKALKADCGPQHRSGWKQ 946
D F + LK LGEG FG+V N G VAVK LK R
Sbjct 461 DRWEFPRYRLKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLS 520
Query 947 EIDILRTLY-HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--------------P 991
E++++++L H +++ GCC D+ +++EYV G L+ YL
Sbjct 521 ELEVMKSLEPHINVVHLLGCCTDKDPT--FVILEYVNRGKLQTYLRSSRAERHYGNTHGK 578
Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
+ + L F Q+ +GM YL ++ IHRDLAARN+L+ +D K+ DFG A+ V
Sbjct 579 SNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITS 638
Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111
Y R + +G P+ W A E L + F SD+WSFG+ ++E++T L
Sbjct 639 KIYER-KSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVT--------------L 683
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
++ + + G RL +P+ C E+Y++M CW + RP F +I +L
Sbjct 684 GSTPYPGISAADVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDK 743
Query 1172 V 1172
+
Sbjct 744 L 744
Score = 220 bits (561), Expect = 1e-58, Method: Composition-based stats.
Identities = 61/330 (18%), Positives = 109/330 (33%), Gaps = 50/330 (15%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ + + LG+G V+ V +
Sbjct 463 WEFPRYRLKFFNILGEGAFGQVWR-------------------CEATNINGNEGITTVAV 503
Query 642 KVLDPSHHDI-ALAFYETASLMSQVS-HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
K L S ++ +M + H ++ + G C ++ EYV G L +L
Sbjct 504 KTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYL 563
Query 700 RRERGH------------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
R R + Q+A + YL ++ ++H ++ RNIL+
Sbjct 564 RSSRAERHYGNTHGKSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILIT---- 619
Query 748 AEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
K++D G ++ + E I W+A E L S D W FG
Sbjct 620 ---DDHTCKVADFGFARDVITSKIYERKSEGKLPIRWMATESLYDNI--FSVKSDIWSFG 674
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859
+ EI G P S ++ + +RL PE +L + C +++P +RP F
Sbjct 675 ILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLF 734
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDP 889
I++ L +L + +
Sbjct 735 AEIIQMLDKLLHTEMDYIELERFPDHNYYN 764
>sp|Q2QLG5|MET_CALJA Hepatocyte growth factor receptor OS=Callithrix
jacchus OX=9483 GN=MET PE=3 SV=1
Length=1381
Score = 273 bits (697), Expect = 8e-74, Method: Composition-based stats.
Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073
++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1255
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV L+EL+T + +T L +G R
Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 232 bits (591), Expect = 9e-61, Method: Composition-based stats.
Identities = 64/328 (20%), Positives = 120/328 (37%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D +G
Sbjct 1350 VHVNATYVNVKCVAPYPSLLSSQDNTDG 1377
>sp|Q1PDV6|PBL27_ARATH Serine/threonine-protein kinase PBL27 OS=Arabidopsis
thaliana OX=3702 GN=PBL27 PE=1 SV=1
Length=513
Score = 258 bits (658), Expect = 8e-74, Method: Composition-based stats.
Identities = 82/298 (28%), Positives = 137/298 (46%), Gaps = 19/298 (6%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
+ LGEG FG+V Y + TG++VAVK L + G Q + E+ +L L+
Sbjct 82 NFRPECLLGEGGFGRV----YKGRLETTGQIVAVKQLDRN-GLQGNREFLVEVLMLSLLH 136
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEG 1010
H +++ G C D ++ LV EY+PLGSL D+L + + + + A +G
Sbjct 137 HPNLVNLIGYCADGDQR--LLVYEYMPLGSLEDHLHDLPPDKEPLDWSTRMTIAAGAAKG 194
Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH + I+RDL + N+LL + K+ DFGLAK P G + + V +
Sbjct 195 LEYLHDKANPPVIYRDLKSSNILLGDGYHPKLSDFGLAKLGPVGDKTH-VSTRVMGTYGY 253
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQMTVLR-LT 1125
APE + SDV+SFGV EL+T + + L+ A+ R
Sbjct 254 CAPEYAMTGQLTLKSDVYSFGVVFLELITGRKAIDNARAPGEHNLVAWARPLFKDRRKFP 313
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV-HEKYQGQAPS 1182
++ + + P + + + C + +A+ RP +++ L + + + APS
Sbjct 314 KMADPSLQGRYPMRGLYQALAVAAMCLQEQAATRPLIGDVVTALTYLASQTFDPNAPS 371
Score = 240 bits (612), Expect = 2e-67, Method: Composition-based stats.
Identities = 73/353 (21%), Positives = 118/353 (33%), Gaps = 63/353 (18%)
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P + L + + K LG+G VY+GRL G
Sbjct 49 PEQKKELTAPKEGPTAHIAAQTFTFRELAAATKNFRPECLLGEGGFGRVYKGRLETTGQ- 107
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
V +K LD + F ++S + H +L +
Sbjct 108 -----------------------IVAVKQLDRNGLQGNREFLVEVLMLSLLHHPNLVNLI 144
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRR---ERGHVPMAWKMVVAQQLASALSYLENK--- 728
G C G + ++V EY+ G L+ L ++ + + +M +A A L YL +K
Sbjct 145 GYCADGDQRLLVYEYMPLGSLEDHLHDLPPDKEPLDWSTRMTIAAGAAKGLEYLHDKANP 204
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERV-----ERIPWLAPE 782
+++ ++ NILL G KLSD G+ LG + + V + APE
Sbjct 205 PVIYRDLKSSNILL-------GDGYHPKLSDFGLAKLGPVGDKTHVSTRVMGTYGYCAPE 257
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH----------- 831
G L+ D + FG LE+ +A +R+P E +
Sbjct 258 YAMTG--QLTLKSDVYSFGVVFLELITGRKAIDNARAPGEHNLVAWARPLFKDRRKFPKM 315
Query 832 -------RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
R P Q + + CL + RP ++ LT L
Sbjct 316 ADPSLQGRYPMRGLYQALAVAAMCLQEQAATRPLIGDVVTALTYLASQTFDPN 368
>sp|Q8AXY6|MUSK_CHICK Muscle, skeletal receptor tyrosine protein
kinase OS=Gallus gallus OX=9031 GN=MUSK PE=2 SV=1
Length=947
Score = 268 bits (685), Expect = 9e-74, Method: Composition-based stats.
Identities = 88/329 (27%), Positives = 149/329 (45%), Gaps = 41/329 (12%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND-GTGEMVAV 929
N +P + + ++ +RD+GEG FG+V MVAV
Sbjct 629 HPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAV 688
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K LK + ++ +++E ++ + +I+K G C K + L+ EY+ G L +Y
Sbjct 689 KMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEY 746
Query 990 LPRHS-----------------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
L S + L A+Q+ GMAYL + ++HRDLA
Sbjct 747 LRDRSPRNLCSLVQGGLEARACLLNPLALCCTSQLCIAKQVAAGMAYLSERKFVHRDLAT 806
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RN L+ + +VKI DFGL++ + +YY+ E+ P+ W PE + ++ SDVW+
Sbjct 807 RNCLVGENMVVKIADFGLSRNMY-SADYYKANENDAIPIRWMPPESIFYNRYTTESDVWA 865
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
+GV L+E+ ++ M + + G L PD CP E+Y+
Sbjct 866 YGVVLWEIFSYGMQ--------------PYYGMAHEEVIYYVRDGNILSCPDNCPLELYN 911
Query 1147 LMKNCWETEASFRPTFENLIPILKTVHEK 1175
LM+ CW + RP+F ++ IL+ ++E+
Sbjct 912 LMRLCWSKLPADRPSFASIHRILERMYER 940
Score = 244 bits (623), Expect = 9e-66, Method: Composition-based stats.
Identities = 70/316 (22%), Positives = 126/316 (40%), Gaps = 58/316 (18%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ I + +G+G V++ R +P V +K+L
Sbjct 651 PRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTM-------------------VAVKML 691
Query 645 DPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+ +LR
Sbjct 692 KEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEYLRDRS 751
Query 704 GH-----------------VPMAW----KMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
P+A ++ +A+Q+A+ ++YL + VH ++ RN L+
Sbjct 752 PRNLCSLVQGGLEARACLLNPLALCCTSQLCIAKQVAAGMAYLSERKFVHRDLATRNCLV 811
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLSTAMD 796
G + +K++D G+ S + I W+ PE + N +T D
Sbjct 812 -------GENMVVKIADFGLSRNMYSADYYKANENDAIPIRWMPPESIF--YNRYTTESD 862
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854
W +G L EI G P + E ++ + + L P+ +L L C + P
Sbjct 863 VWAYGVVLWEIFSYGMQPYYGMAHEEVIYYVRDGNILSCPDNCPLELYNLMRLCWSKLPA 922
Query 855 QRPSFRTILRDLTRLQ 870
RPSF +I R L R+
Sbjct 923 DRPSFASIHRILERMY 938
>sp|Q2QL89|MET_MICMU Hepatocyte growth factor receptor OS=Microcebus
murinus OX=30608 GN=MET PE=3 SV=1
Length=1382
Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats.
Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073
++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L
Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1256
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV L+EL+T + +T L +G R
Sbjct 1257 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1302
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1303 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348
Score = 230 bits (587), Expect = 3e-60, Method: Composition-based stats.
Identities = 64/328 (20%), Positives = 119/328 (36%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1119
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D G
Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNING 1378
>sp|Q2QLC0|MET_PLEMO Hepatocyte growth factor receptor OS=Plecturocebus
moloch OX=9523 GN=MET PE=3 SV=1
Length=1381
Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats.
Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073
++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1255
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV L+EL+T + +T L +G R
Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 231 bits (590), Expect = 1e-60, Method: Composition-based stats.
Identities = 64/328 (20%), Positives = 120/328 (37%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D +G
Sbjct 1350 VHVNATYVNVKCVAPYPSLLSSQDNADG 1377
>sp|Q07DY1|MET_NOMLE Hepatocyte growth factor receptor OS=Nomascus
leucogenys OX=61853 GN=MET PE=3 SV=1
Length=1390
Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats.
Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073
++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1255
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV L+EL+T + +T L +G R
Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 229 bits (584), Expect = 6e-60, Method: Composition-based stats.
Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKR 895
+ + V
Sbjct 1350 VHVNATYVNVKCVAPYP 1366
>sp|P08581|MET_HUMAN Hepatocyte growth factor receptor OS=Homo
sapiens OX=9606 GN=MET PE=1 SV=4
Length=1390
Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats.
Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073
++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1255
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV L+EL+T + +T L +G R
Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 229 bits (585), Expect = 6e-60, Method: Composition-based stats.
Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKR 895
+ + V
Sbjct 1350 VHVNATYVNVKCVAPYP 1366
>sp|Q2IBF2|MET_GORGO Hepatocyte growth factor receptor OS=Gorilla
gorilla gorilla OX=9595 GN=MET PE=3 SV=1
Length=1390
Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats.
Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073
++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1255
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV L+EL+T + +T L +G R
Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 229 bits (584), Expect = 6e-60, Method: Composition-based stats.
Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKR 895
+ + V
Sbjct 1350 VHVNATYVNVKCVAPYP 1366
>sp|Q2QLF1|MET_PANTR Hepatocyte growth factor receptor OS=Pan
troglodytes OX=9598 GN=MET PE=3 SV=1
Length=1390
Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats.
Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073
++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1255
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV L+EL+T + +T L +G R
Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 229 bits (584), Expect = 6e-60, Method: Composition-based stats.
Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKR 895
+ + V
Sbjct 1350 VHVNATYVNVKCVAPYP 1366
>sp|Q2IBD8|MET_PONAB Hepatocyte growth factor receptor OS=Pongo
abelii OX=9601 GN=MET PE=3 SV=1
Length=1390
Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats.
Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073
++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1255
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV L+EL+T + +T L +G R
Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 229 bits (584), Expect = 6e-60, Method: Composition-based stats.
Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKR 895
+ + V
Sbjct 1350 VHVNATYVNVKCVAPYP 1366
>sp|Q07DZ1|MET_COLGU Hepatocyte growth factor receptor OS=Colobus
guereza OX=33548 GN=MET PE=3 SV=1
Length=1381
Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats.
Identities = 90/285 (32%), Positives = 137/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1256
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1303 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 229 bits (584), Expect = 7e-60, Method: Composition-based stats.
Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKR 895
+ + V
Sbjct 1350 VHVNATYVNVKCVAPYP 1366
>sp|P51813|BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX OS=Homo
sapiens OX=9606 GN=BMX PE=1 SV=1
Length=675
Score = 262 bits (670), Expect = 1e-73, Method: Composition-based stats.
Identities = 84/436 (19%), Positives = 162/436 (37%), Gaps = 64/436 (15%)
Query 449 DGIHGPLLEPFVQAKLRPE--DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFP 506
D G + + LR + +G +++ S+ + TV+ S+A + + ++ +
Sbjct 295 DWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQVG---MYTVSLFSKAVNDKKGT-VKHYH 350
Query 507 IEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRG 566
+ + F S+ +L Q + LR +
Sbjct 351 VHTNAENKLYLAENYCFDSIPKLIHYHQHN---SAGMITRLRHP------------VSTK 395
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
A P +++L + ++EIT L LG G V G+ +
Sbjct 396 ANKVPDSVSLGN-GIWELKREEITLLKELGSGQFGVVQLGKWKG---------------- 438
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+ V +K++ F++ A M ++SH L +GVC + +V
Sbjct 439 ---------QYDVAVKMIKEGSMS-EDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIV 488
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TEY+ +G L +LR + + + + + +++LE+ +H ++ RN L+ R
Sbjct 489 TEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDR-- 546
Query 747 LAEGTSPFIKLSDPGVGLGALSREE--RVER---IPWLAPECLPGGANSLSTAMDKWGFG 801
+K+SD G+ L + V + W APE S+ D W FG
Sbjct 547 -----DLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFH--YFKYSSKSDVWAFG 599
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859
+ E+ G+ P S+ + HRL P + + + C P +RP+F
Sbjct 600 ILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTF 659
Query 860 RTILRDLTRLQPHNLA 875
+ +L + L+ +
Sbjct 660 QQLLSSIEPLREKDKH 675
Score = 259 bits (661), Expect = 1e-72, Method: Composition-based stats.
Identities = 98/351 (28%), Positives = 156/351 (44%), Gaps = 29/351 (8%)
Query 829 RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA-- 886
+ + + + +L + C P + + H ++ PDS +
Sbjct 347 KHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLG 406
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
+ + + +++LG G FG V L + D VAVK +K G + Q
Sbjct 407 NGIWELKREEITLLKELGSGQFGVVQLGKWKGQYD-----VAVKMIKE--GSMSEDEFFQ 459
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFA 1004
E + L H ++K+ G C E + +V EY+ G L +YL H GL QLL
Sbjct 460 EAQTMMKLSHPKLVKFYGVCSK--EYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMC 517
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+CEGMA+L + +IHRDLAARN L+D D VK+ DFG+ + V + + Y P
Sbjct 518 YDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLD--DQYVSSVGTKFP 575
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
V W APE +K+ SDVW+FG+ ++E+ + L ++
Sbjct 576 VKWSAPEVFHYFKYSSKSDVWAFGILMWEVFS--------------LGKQPYDLYDNSQV 621
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+ +G RL RP +Y +M +CW RPTF+ L+ ++ + EK
Sbjct 622 VLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLREK 672
>sp|Q09YL1|MET_ATEGE Hepatocyte growth factor receptor OS=Ateles
geoffroyi OX=9509 GN=MET PE=3 SV=1
Length=1381
Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats.
Identities = 90/285 (32%), Positives = 137/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1256
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1303 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSAFIGE 1347
Score = 231 bits (589), Expect = 2e-60, Method: Composition-based stats.
Identities = 64/328 (20%), Positives = 120/328 (37%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSAFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D +G
Sbjct 1350 VHVNATYVNVKCVAPYPSLLSSQDNADG 1377
>sp|Q09YH7|MET_SAIBB Hepatocyte growth factor receptor OS=Saimiri
boliviensis boliviensis OX=39432 GN=MET PE=3 SV=1
Length=1381
Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats.
Identities = 90/285 (32%), Positives = 137/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1256
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1303 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 231 bits (589), Expect = 2e-60, Method: Composition-based stats.
Identities = 64/328 (20%), Positives = 120/328 (37%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D +G
Sbjct 1350 VHVNATYVNVKCVAPYPSLLSSQDNADG 1377
>sp|F4JZW1|PBL13_ARATH Serine/threonine-protein kinase PBL13 OS=Arabidopsis
thaliana OX=3702 GN=PBL13 PE=1 SV=1
Length=494
Score = 257 bits (656), Expect = 1e-73, Method: Composition-based stats.
Identities = 82/290 (28%), Positives = 128/290 (44%), Gaps = 14/290 (5%)
Query 901 RDLGEGHFGKVSLYCYDPTND--GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
LGEG FG V D + VAVK L D HR + E+ L L H +
Sbjct 80 NFLGEGGFGPVHKGFIDDKLRPGLKAQPVAVKLLDLDGLQGHRE-FMTEVMCLGKLKHPN 138
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLH 1015
++K G C ++ + LV E++P GSL L R + L A + +G+ +LH
Sbjct 139 LVKLIGYCCEEAHR--LLVYEFMPRGSLESQLFRRCSLPLPWTTRLNIAYEAAKGLQFLH 196
Query 1016 A--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ I+RD A N+LLD+D K+ DFGLAK P+G + + V + APE +
Sbjct 197 EAEKPIIYRDFKASNILLDSDYTAKLSDFGLAKDGPQGDDTH-VSTRVMGTQGYAAPEYI 255
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMT-VLRLTELLERG 1131
SDV+SFGV L ELLT S + ++ L+ A+ + +L +++
Sbjct 256 MTGHLTAKSDVYSFGVVLLELLTGRKSVDIARSSRKETLVEWARPMLNDARKLGRIMDPR 315
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
+ + L C RP ++ +L+ + + Y+ P
Sbjct 316 LEDQYSETGARKAATLAYQCLRYRPKTRPDISTVVSVLQDIKD-YKDDIP 364
Score = 241 bits (616), Expect = 3e-68, Method: Composition-based stats.
Identities = 82/405 (20%), Positives = 149/405 (37%), Gaps = 64/405 (16%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
L++ + RV + + + LG+G V++G + +D L PG
Sbjct 59 SDLHVFTQAELRVITQSFSSSNFLGEGGFGPVHKGFI---------------DDKLRPGL 103
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+ V +K+LD F + ++ H +L + G C ++V E++
Sbjct 104 ---KAQPVAVKLLDLDGLQGHREFMTEVMCLGKLKHPNLVKLIGYCCEEAHRLLVYEFMP 160
Query 692 HGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLA 748
G L+ L R +P ++ +A + A L +L K +++ + NILL
Sbjct 161 RGSLESQLFRRCSLPLPWTTRLNIAYEAAKGLQFLHEAEKPIIYRDFKASNILLD----- 215
Query 749 EGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+ KLSD G+ ++ + + APE + G L+ D + FG
Sbjct 216 --SDYTAKLSDFGLAKDGPQGDDTHVSTRVMGTQGYAAPEYIMTG--HLTAKSDVYSFGV 271
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE------PSCPQL------------ATL 844
LLE+ ++ +RS ++ + L + P+L ATL
Sbjct 272 VLLELLTGRKSVDIARSSRKETLVEWARPMLNDARKLGRIMDPRLEDQYSETGARKAATL 331
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
QCL Y P RP T++ L ++ + + + + + P K + D
Sbjct 332 AYQCLRYRPKTRPDISTVVSVLQDIKDYKDDIPIGIFTYTVPTKPRREVKETSLQNFDKP 391
Query 905 EGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
SL +D T VK D Q+ ++E+
Sbjct 392 RRETKVTSLQNFDKTRRE------VK----DTSLQNFDKTRREVK 426
>sp|P34152|FAK1_MOUSE Focal adhesion kinase 1 OS=Mus musculus
OX=10090 GN=Ptk2 PE=1 SV=4
Length=1052
Score = 269 bits (688), Expect = 1e-73, Method: Composition-based stats.
Identities = 100/301 (33%), Positives = 148/301 (49%), Gaps = 24/301 (8%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQH 940
P++ + ++ R +GEG FG V Y P N VA+K K
Sbjct 407 YTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGVYLSPENPALA--VAIKTCKNCTSDSV 464
Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLA 998
R + QE +R H HI+K G E + ++ME LG LR +L ++S+ LA
Sbjct 465 REKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLA 521
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
L+L+A Q+ +AYL ++ ++HRD+AARNVL+ ++ VK+GDFGL++ + + Y
Sbjct 522 SLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKA 579
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
G P+ W APE + +F ASDVW FGV ++E+L H
Sbjct 580 SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ--------------G 625
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
+ + +E GERLP P CP +Y LM CW + S RP F L L T+ E+ +
Sbjct 626 VKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKV 685
Query 1179 Q 1179
Q
Sbjct 686 Q 686
Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats.
Identities = 70/305 (23%), Positives = 124/305 (41%), Gaps = 39/305 (13%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
T + + + ++ I +G+G +V++G V
Sbjct 406 TYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQG---------------------VYLSP 444
Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
L V +K D F + A M Q H H+ + GV P ++ E
Sbjct 445 ENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCT 503
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G L +L+ + + +A ++ A QL++AL+YLE+K VH ++ RN+L++ +
Sbjct 504 LGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS-------S 556
Query 752 SPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+ +KL D G+ I W+APE + ++A D W FG + E
Sbjct 557 NDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWE 614
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
I G P Q ++ + R +P P L +L ++C Y+P++RP F +
Sbjct 615 ILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKA 674
Query 865 DLTRL 869
L+ +
Sbjct 675 QLSTI 679
Score = 38.5 bits (88), Expect = 0.45, Method: Composition-based stats.
Identities = 34/193 (18%), Positives = 70/193 (36%), Gaps = 29/193 (15%)
Query 120 PAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHF 179
P ++ Q + D + + ++Q K +++ ++A ++
Sbjct 117 PEEWKYELRIRYLPKGFLNQFTE--DKPTLNFFYQQVKSDYMQEIA-----DQVDQEIAL 169
Query 180 KNESLGM--AFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNV 237
K L + ++ + AL E + K K P+S ++ + R ++
Sbjct 170 KLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTL--RKLIQQT 227
Query 238 FRRFLRDFQPGRLSQQMVMVKYLATLERLAP--RFGTERVP-------VCHLRLLAQAEG 288
FR+F L+++ ++K+ E L+P RF E + + L E
Sbjct 228 FRQF------ANLNREESILKF---FEILSPVYRFDKECFKCALGSSWIISVELAIGPEE 278
Query 289 EPCYIRDSGVAPT 301
Y+ D G PT
Sbjct 279 GISYLTDKGCNPT 291
>sp|Q07DV8|MET_AOTNA Hepatocyte growth factor receptor OS=Aotus
nancymaae OX=37293 GN=MET PE=3 SV=1
Length=1381
Score = 272 bits (695), Expect = 1e-73, Method: Composition-based stats.
Identities = 90/285 (32%), Positives = 137/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1256
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1303 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 232 bits (591), Expect = 1e-60, Method: Composition-based stats.
Identities = 64/328 (20%), Positives = 120/328 (37%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D +G
Sbjct 1350 VHVNATYVNVKCVAPYPSLLSSQDNPDG 1377
>sp|Q2IBG7|MET_EULMM Hepatocyte growth factor receptor OS=Eulemur
macaco macaco OX=30603 GN=MET PE=3 SV=1
Length=1382
Score = 272 bits (695), Expect = 1e-73, Method: Composition-based stats.
Identities = 90/285 (32%), Positives = 137/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348
Score = 230 bits (587), Expect = 3e-60, Method: Composition-based stats.
Identities = 64/328 (20%), Positives = 119/328 (36%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1119
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D G
Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNVNG 1378
>sp|Q54TA1|DRKC_DICDI Probable serine/threonine-protein kinase
drkC OS=Dictyostelium discoideum OX=44689 GN=drkC PE=3 SV=1
Length=749
Score = 264 bits (674), Expect = 1e-73, Method: Composition-based stats.
Identities = 76/279 (27%), Positives = 122/279 (44%), Gaps = 29/279 (10%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA--LKADCGPQHRSGWKQEIDILRTLYHE 957
+G G +V + G +VA+K L + + QE I+ L H
Sbjct 494 QNRIGRGSCAEVFTGTWR------GIIVAIKKAKLLNEDDEDFLNELAQEATIMSQLRHP 547
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015
+I ++ G C + E + +VMEY+PLGSL L S + ++ A I +GM YLH
Sbjct 548 NICQFLGTCNNPPE--ILIVMEYMPLGSLYRILHDPSISLDWPRMKSMALDIAKGMNYLH 605
Query 1016 --AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRDL + N+L+D VKI DFGL+ + + +P W APE L
Sbjct 606 CCDPIVIHRDLKSHNLLVDEHYRVKISDFGLSTRFKKHLDKKTAMTPVGTPC-WTAPEVL 664
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ + +DV+SF + L+E++T D QG T + + + R
Sbjct 665 RNDPYTEKADVFSFAIVLWEIVTREDPY--------------QGMPTFQIVISVGQHKLR 710
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P + L+ CW + RP+F+ ++ L+ +
Sbjct 711 PIVPPQVSAPFTRLITECWSEDPQQRPSFQEIVKRLEAM 749
Score = 233 bits (594), Expect = 4e-63, Method: Composition-based stats.
Identities = 75/418 (18%), Positives = 143/418 (34%), Gaps = 57/418 (14%)
Query 472 LIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGA 531
++ +++ P +T+ F I ++ ++ + +
Sbjct 369 MLQSNSTTPSDYNVTIQLSEDGGSSF--CLNTTFFIYTAASIPFVKPTSPNYQKIIYIVV 426
Query 532 ALQGCLLR--AGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQ-----LSFHRV 584
+ +L A F +R + S + G R+ L +
Sbjct 427 GVGIAVLLIIAVGIYFIIRLRIKNKRLNGSKHALPIGINDDERSPLLKTDYKTLFEIKPI 486
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV- 643
D EI + +G+G+ V+ G R + V +K
Sbjct 487 DISEIVVQNRIGRGSCAEVFTGTWRG--------------------------IIVAIKKA 520
Query 644 --LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
L+ D + A++MSQ+ H ++ G C PE ++V EY+ G L L
Sbjct 521 KLLNEDDEDFLNELAQEATIMSQLRHPNICQFLGTCNNPPEILIVMEYMPLGSLYRILHD 580
Query 702 ERGHVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ +A +A ++YL + ++H ++ N+L+ +K+SD
Sbjct 581 PSISLDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDE-------HYRVKISD 633
Query 760 PGVG------LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ L + V W APE L + + D + F L EI +
Sbjct 634 FGLSTRFKKHLDKKTAMTPVGTPCWTAPEVLRN--DPYTEKADVFSFAIVLWEIVTREDP 691
Query 814 PLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ Q + R +P L ++C + +P QRPSF+ I++ L +
Sbjct 692 YQGMPTFQIVISVGQHKLRPIVPPQVSAPFTRLITECWSEDPQQRPSFQEIVKRLEAM 749
>sp|A0M8R7|MET_PAPAN Hepatocyte growth factor receptor OS=Papio
anubis OX=9555 GN=MET PE=3 SV=1
Length=1381
Score = 272 bits (695), Expect = 1e-73, Method: Composition-based stats.
Identities = 90/285 (32%), Positives = 137/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1256
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1303 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 229 bits (583), Expect = 8e-60, Method: Composition-based stats.
Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKR 895
+ + V
Sbjct 1350 VHVNATYVNVKCVAPYP 1366
>sp|Q1PE89|PBL24_ARATH Probable serine/threonine-protein kinase
PBL24 OS=Arabidopsis thaliana OX=3702 GN=PBL24 PE=2 SV=1
Length=389
Score = 253 bits (646), Expect = 1e-73, Method: Composition-based stats.
Identities = 89/340 (26%), Positives = 137/340 (40%), Gaps = 18/340 (5%)
Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910
YE P N + S ++ +GEG FG+
Sbjct 25 YEQQNLPRNDRRQITTWEAVGTNKESPKNIKAKSFKFRELATATNSFRQEFLIGEGGFGR 84
Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970
V Y + TG++VAVK L + G Q + EI L L+H ++ G C D
Sbjct 85 V----YKGKMEKTGQVVAVKQLDRN-GLQGNREFLVEIFRLSLLHHPNLANLIGYCLDGD 139
Query 971 EKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHR 1022
++ LV E++PLGSL D+L + + + A +G+ YLH + I+R
Sbjct 140 QR--LLVHEFMPLGSLEDHLLDVVVGQQPLDWNSRIRIALGAAKGLEYLHEKANPPVIYR 197
Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082
D + N+LL+ D K+ DFGLAK G + V + APE K + S
Sbjct 198 DFKSSNILLNVDFDAKLSDFGLAKLGSVG-DTQNVSSRVVGTYGYCAPEYHKTGQLTVKS 256
Query 1083 DVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQG-QMTVLRLTELLERGERLPRPDKC 1140
DV+SFGV L EL+T + P L+ AQ R EL + + P+K
Sbjct 257 DVYSFGVVLLELITGKRVIDTTRPCHEQNLVTWAQPIFREPNRFPELADPLLQGEFPEKS 316
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180
+ + C + E RP +++ L + + +
Sbjct 317 LNQAVAIAAMCLQEEPIVRPLISDVVTALSFMSTETGSPS 356
Score = 230 bits (587), Expect = 1e-65, Method: Composition-based stats.
Identities = 72/346 (21%), Positives = 122/346 (35%), Gaps = 65/346 (19%)
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEGS 613
+ + + + SP+ + F + Q +G+G VY+G++ G
Sbjct 36 RQITTWEAVGTNKESPKNIKAKSFKFRELATATNSFRQEFLIGEGGFGRVYKGKMEKTGQ 95
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
V +K LD + F +S + H +LA +
Sbjct 96 ------------------------VVAVKQLDRNGLQGNREFLVEIFRLSLLHHPNLANL 131
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYLENK-- 728
G C+ G + ++V E++ G L+ L G P+ W ++ +A A L YL K
Sbjct 132 IGYCLDGDQRLLVHEFMPLGSLEDHLLDVVVGQQPLDWNSRIRIALGAAKGLEYLHEKAN 191
Query 729 -NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAP 781
+++ + NILL KLSD G+ + + V + AP
Sbjct 192 PPVIYRDFKSSNILLN-------VDFDAKLSDFGLAKLGSVGDTQNVSSRVVGTYGYCAP 244
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ------HRLPE 835
E G L+ D + FG LLE+ +R E+ Q +R PE
Sbjct 245 EYHKTG--QLTVKSDVYSFGVVLLELITGKRVIDTTRPCHEQNLVTWAQPIFREPNRFPE 302
Query 836 PSCPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ P L + + CL EP RP ++ L+ +
Sbjct 303 LADPLLQGEFPEKSLNQAVAIAAMCLQEEPIVRPLISDVVTALSFM 348
>sp|Q07E48|MET_DASNO Hepatocyte growth factor receptor OS=Dasypus
novemcinctus OX=9361 GN=MET PE=3 SV=1
Length=1381
Score = 272 bits (695), Expect = 1e-73, Method: Composition-based stats.
Identities = 91/286 (32%), Positives = 140/286 (49%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V ++D AVK+L S + E I++ H
Sbjct 1080 HFNEVIGRGHFGCVYHGTLLDSDDK-KIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073
++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L
Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1256
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV L+EL+T + +T L +G R
Sbjct 1257 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1302
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1303 LLQPEYCPDRLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348
Score = 228 bits (581), Expect = 1e-59, Method: Composition-based stats.
Identities = 64/333 (19%), Positives = 121/333 (36%), Gaps = 46/333 (14%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L +++ +K L+
Sbjct 1081 FNEVIGRGHFGCVYHGTLLDSD---------------------DKKIHCAVKSLNRITDI 1119
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE +L + +C + RPSF ++ ++ + + +
Sbjct 1291 FDITVYLLQGRRLLQPEYCPDRLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911
+ + + L DL G+V
Sbjct 1351 VHVNATYVNVKCIAPYPSLLSQDDLD----GEV 1379
>sp|O35346|FAK1_RAT Focal adhesion kinase 1 OS=Rattus norvegicus
OX=10116 GN=Ptk2 PE=1 SV=1
Length=1055
Score = 269 bits (688), Expect = 1e-73, Method: Composition-based stats.
Identities = 100/301 (33%), Positives = 148/301 (49%), Gaps = 24/301 (8%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQH 940
P++ + ++ R +GEG FG V Y P N VA+K K
Sbjct 407 YTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGVYLSPENPALA--VAIKTCKNCTSDSV 464
Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLA 998
R + QE +R H HI+K G E + ++ME LG LR +L ++S+ LA
Sbjct 465 REKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLA 521
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
L+L+A Q+ +AYL ++ ++HRD+AARNVL+ ++ VK+GDFGL++ + + Y
Sbjct 522 SLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKA 579
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
G P+ W APE + +F ASDVW FGV ++E+L H
Sbjct 580 SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ--------------G 625
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
+ + +E GERLP P CP +Y LM CW + S RP F L L T+ E+ +
Sbjct 626 VKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKV 685
Query 1179 Q 1179
Q
Sbjct 686 Q 686
Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats.
Identities = 70/305 (23%), Positives = 124/305 (41%), Gaps = 39/305 (13%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
T + + + ++ I +G+G +V++G V
Sbjct 406 TYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQG---------------------VYLSP 444
Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
L V +K D F + A M Q H H+ + GV P ++ E
Sbjct 445 ENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCT 503
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G L +L+ + + +A ++ A QL++AL+YLE+K VH ++ RN+L++ +
Sbjct 504 LGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS-------S 556
Query 752 SPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+ +KL D G+ I W+APE + ++A D W FG + E
Sbjct 557 NDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWE 614
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
I G P Q ++ + R +P P L +L ++C Y+P++RP F +
Sbjct 615 ILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKA 674
Query 865 DLTRL 869
L+ +
Sbjct 675 QLSTI 679
Score = 37.4 bits (85), Expect = 1.1, Method: Composition-based stats.
Identities = 34/193 (18%), Positives = 70/193 (36%), Gaps = 29/193 (15%)
Query 120 PAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHF 179
P ++ Q + D + + ++Q K +++ ++A ++
Sbjct 117 PEEWKYELRIRYLPKGFLNQFTE--DKPTLNFFYQQVKSDYMLEIA-----DQVDQDIAL 169
Query 180 KNESLGM--AFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNV 237
K L + ++ + AL E + K K P+S ++ + R ++
Sbjct 170 KLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTL--RKLIQQT 227
Query 238 FRRFLRDFQPGRLSQQMVMVKYLATLERLAP--RFGTERVP-------VCHLRLLAQAEG 288
FR+F L+++ ++K+ E L+P RF E + + L E
Sbjct 228 FRQF------ANLNREESILKF---FEILSPVYRFDKECFKCALGSSWIISVELAIGPEE 278
Query 289 EPCYIRDSGVAPT 301
Y+ D G PT
Sbjct 279 GISYLTDKGCNPT 291
>sp|Q2IBA6|MET_CHLAE Hepatocyte growth factor receptor OS=Chlorocebus
aethiops OX=9534 GN=MET PE=1 SV=1
Length=1381
Score = 272 bits (695), Expect = 1e-73, Method: Composition-based stats.
Identities = 90/285 (32%), Positives = 137/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V NDG AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1256
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1303 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347
Score = 229 bits (583), Expect = 8e-60, Method: Composition-based stats.
Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G+++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKR 895
+ + V
Sbjct 1350 VHVNATYVNVKCVAPYP 1366
>sp|O49840|PBL3_ARATH Probable serine/threonine-protein kinase
PBL3 OS=Arabidopsis thaliana OX=3702 GN=PBL3 PE=1 SV=1
Length=426
Score = 254 bits (649), Expect = 1e-73, Method: Composition-based stats.
Identities = 89/288 (31%), Positives = 130/288 (45%), Gaps = 16/288 (6%)
Query 903 LGEGHFGKVSLYCYDPT-----NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LGEG FG V D T G+G +VAVK LK + G Q W E++ L L H
Sbjct 89 LGEGGFGYVFKGWIDGTTLTASKPGSGIVVAVKKLKTE-GYQGHKEWLTEVNYLGQLSHP 147
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYL 1014
+++K G C + GE L LV E++P GSL ++L R + A + A +G+ +L
Sbjct 148 NLVKLVGYCVE-GENRL-LVYEFMPKGSLENHLFRRGAQPLTWAIRMKVAIGAAKGLTFL 205
Query 1015 H--AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
H I+RD A N+LLD + K+ DFGLAKA P G + + V + APE
Sbjct 206 HDAKSQVIYRDFKAANILLDAEFNSKLSDFGLAKAGPTGDKTH-VSTQVMGTHGYAAPEY 264
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE-LIGIAQGQM-TVLRLTELLER 1130
+ + SDV+SFGV L ELL+ + + L+ A + +L +++
Sbjct 265 VATGRLTAKSDVYSFGVVLLELLSGRRAVDKSKVGMEQSLVDWATPYLGDKRKLFRIMDT 324
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P K L C +A RP ++ L + G
Sbjct 325 RLGGQYPQKGAYTAASLALQCLNPDAKLRPKMSEVLAKLDQLESTKPG 372
Score = 235 bits (599), Expect = 1e-66, Method: Composition-based stats.
Identities = 73/341 (21%), Positives = 128/341 (38%), Gaps = 55/341 (16%)
Query 560 NLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
+L R + NL +F+ + + S LG+G V++G +
Sbjct 52 SLPTPRTEGEILSSPNLKAFTFNELKNATRNFRPDSLLGEGGFGYVFKGWI--------- 102
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
+ + G + V +K L + + + + Q+SH +L + G C
Sbjct 103 ------DGTTLTASKPGSGIVVAVKKLKTEGYQGHKEWLTEVNYLGQLSHPNLVKLVGYC 156
Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN--KNLVHG 733
V G ++V E++ G L+ L R RG P+ W +M VA A L++L + +++
Sbjct 157 VEGENRLLVYEFMPKGSLENHLFR-RGAQPLTWAIRMKVAIGAAKGLTFLHDAKSQVIYR 215
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGG 787
+ NILL KLSD G+ + ++ + + APE + G
Sbjct 216 DFKAANILLD-------AEFNSKLSDFGLAKAGPTGDKTHVSTQVMGTHGYAAPEYVATG 268
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR------------------ 829
L+ D + FG LLE+ A +S+ E+
Sbjct 269 --RLTAKSDVYSFGVVLLELLSGRRAVDKSKVGMEQSLVDWATPYLGDKRKLFRIMDTRL 326
Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ P+ A+L QCL + RP +L L +L+
Sbjct 327 GGQYPQKGAYTAASLALQCLNPDAKLRPKMSEVLAKLDQLE 367
>sp|Q09YK0|MET_MUNMU Hepatocyte growth factor receptor OS=Muntiacus
muntjak OX=9888 GN=MET PE=3 SV=1
Length=1382
Score = 272 bits (695), Expect = 2e-73, Method: Composition-based stats.
Identities = 90/285 (32%), Positives = 136/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V ND AVK+L S + E I++ H
Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLA 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ V + Y + PV W A E L+
Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQ 1257
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 LQPEYCPDALYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348
Score = 229 bits (583), Expect = 8e-60, Method: Composition-based stats.
Identities = 63/328 (19%), Positives = 118/328 (36%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L +++ +K L+
Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1119
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMEYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDVYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1291 FDITVYLLQGRRLLQPEYCPDALYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D G
Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNVNG 1378
>sp|Q60750|EPHA1_MOUSE Ephrin type-A receptor 1 OS=Mus musculus
OX=10090 GN=Epha1 PE=1 SV=2
Length=977
Score = 268 bits (684), Expect = 2e-73, Method: Composition-based stats.
Identities = 87/307 (28%), Positives = 140/307 (46%), Gaps = 20/307 (7%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
L+P+ +L +GEG FG+V + + V
Sbjct 596 WLKPYVDLQAYEDPAQGALDFAQELDPAWLIVDTVIGEGEFGEVYRGALRLPSQDC-KTV 654
Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
A+K LK + + +E I+ H HI++ +G + K + ++ E++ G+L
Sbjct 655 AIKTLKDTSPDGYWWNFLREATIMGQFNHPHILRLEGVITKR--KPIMIITEFMENGALD 712
Query 988 DYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L + QL+ I GM L +Y+HRDLAARN+L++ + K+ DFGL
Sbjct 713 AFLKEREDQLAPGQLVAMLLGIASGMNCLSGHNYVHRDLAARNILVNQNLCCKVSDFGLT 772
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
+ + + Y + G P+ W APE + F ASDVWSFG+ ++E+L+ D
Sbjct 773 RLLDDFDGTYET-QGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDK----- 826
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
G+M+ + + +E G RLP P CP +Y LMKNCW + + RP F L
Sbjct 827 ---------PYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFLQL 877
Query 1166 IPILKTV 1172
L+ +
Sbjct 878 QAHLEQL 884
Score = 249 bits (637), Expect = 3e-67, Method: Composition-based stats.
Identities = 73/302 (24%), Positives = 120/302 (40%), Gaps = 39/302 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D + + +G+G VY G LR+ V +
Sbjct 618 QELDPAWLIVDTVIGEGEFGEVYRGALRLPSQDCK---------------------TVAI 656
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + D F A++M Q +H H+ + GV + +++TE++E+G LD +L+
Sbjct 657 KTLKDTSPDGYWWNFLREATIMGQFNHPHILRLEGVITKRKPIMIITEFMENGALDAFLK 716
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ + + +AS ++ L N VH ++ RNIL+ + + K+SD
Sbjct 717 EREDQLAPGQLVAMLLGIASGMNCLSGHNYVHRDLAARNILVNQ-------NLCCKVSDF 769
Query 761 GVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ G + I W APE + +TA D W FG + E+ G+ P
Sbjct 770 GLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRI--FTTASDVWSFGIVMWEVLSFGDKP 827
Query 815 LQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
S E + +RLP P CP L L C Y+ +RP F + L +L
Sbjct 828 YGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFLQLQAHLEQLLTD 887
Query 873 NL 874
Sbjct 888 PH 889
>sp|Q00PJ8|MET_ATEAB Hepatocyte growth factor receptor OS=Atelerix
albiventris OX=9368 GN=MET PE=3 SV=1
Length=1382
Score = 271 bits (694), Expect = 2e-73, Method: Composition-based stats.
Identities = 89/285 (31%), Positives = 137/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V ND AVK+L S + E I++ H
Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD + VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1198 SKKFVHRDLAARNCMLDENFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348
Score = 228 bits (580), Expect = 2e-59, Method: Composition-based stats.
Identities = 60/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L +++ +K L+
Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1119
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L + +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------NFTVKVADFGLARDMYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKR 895
+ + V
Sbjct 1351 VHVNATYVNIKCVAPYP 1367
>sp|Q09147|FGFR2_DROME Fibroblast growth factor receptor homolog
2 OS=Drosophila melanogaster OX=7227 GN=btl PE=2 SV=3
Length=1052
Score = 269 bits (687), Expect = 2e-73, Method: Composition-based stats.
Identities = 99/334 (30%), Positives = 159/334 (48%), Gaps = 44/334 (13%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---EMVAVKALKAD 935
+ P ++ L LGEG FG+V + + +VAVK +K +
Sbjct 694 FNEYEFPLDSNWEIPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEE 753
Query 936 CGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994
+ +E+++++ + H +II GCC G L +++EY P G+L+D+L ++
Sbjct 754 HTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGG--PLWVIVEYAPHGNLKDFLKQNR 811
Query 995 ------------------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030
+G +L FA QI GM YL ++ IHRDLAARNVL
Sbjct 812 PGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVL 871
Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
+ + ++KI DFGLA+ + + EYYR +G P+ W APE L+E K+ SDVWS+GV
Sbjct 872 VSDGYVMKIADFGLARDIQD-TEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVL 930
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
L+E++T+ D ++ L L G+R+ +P KC +Y +M+
Sbjct 931 LWEIMTYGDQPY-------------PHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQ 977
Query 1151 CWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
CW E+ RPTF L+ + ++ +
Sbjct 978 CWHFESCARPTFAELVESFDGILQQASSNPNDAY 1011
Score = 236 bits (603), Expect = 8e-63, Method: Composition-based stats.
Identities = 64/349 (18%), Positives = 124/349 (36%), Gaps = 59/349 (17%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
S + +++++ S LG+G V + E +P
Sbjct 696 EYEFPLDSNWEIPRQQLSLGSILGEGAFGRV-----------------VMAEAEGLPRSP 738
Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690
+ E V +K++ H D +A +M + H ++ + G C +G ++ EY
Sbjct 739 QLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYA 798
Query 691 EHGPLDVWLRRERG----------------------HVPMAWKMVVAQQLASALSYLENK 728
HG L +L++ R H+ A Q+A + YL ++
Sbjct 799 PHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASR 858
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPE 782
+H ++ RN+L++ +K++D G+ R+ R+P W+APE
Sbjct 859 RCIHRDLAARNVLVS-------DGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPE 911
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCP 839
L + D W +G L EI G+ P +E+ + ++ P
Sbjct 912 SLQE--KKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSL 969
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASD 888
+ + QC +E RP+F ++ + ++ D
Sbjct 970 NIYVVMRQCWHFESCARPTFAELVESFDGILQQASSNPNDAYLDLSMPM 1018
>sp|Q62838|MUSK_RAT Muscle, skeletal receptor tyrosine protein
kinase OS=Rattus norvegicus OX=10116 GN=Musk PE=1 SV=1
Length=868
Score = 265 bits (678), Expect = 2e-73, Method: Composition-based stats.
Identities = 86/336 (26%), Positives = 150/336 (45%), Gaps = 43/336 (13%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND-GTGEMVAV 929
N +P + + ++ +RD+GEG FG+V MVAV
Sbjct 548 HPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAV 607
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K LK + ++ +++E ++ + +I+K G C K + L+ EY+ G L ++
Sbjct 608 KMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEF 665
Query 990 LPR-------------------------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDL 1024
L + A+ L A+Q+ GMAYL + ++HRDL
Sbjct 666 LRSMSPHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDL 725
Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084
A RN L+ + +VKI DFGL++ + +YY+ + P+ W PE + ++ SDV
Sbjct 726 ATRNCLVGENMVVKIADFGLSRNIY-SADYYKADGNDAIPIRWMPPESIFYNRYTTESDV 784
Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144
W++GV L+E+ ++ M + + G L P+ CP E+
Sbjct 785 WAYGVVLWEIFSYGLQ--------------PYYGMAHEEVIYYVRDGNILACPENCPLEL 830
Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180
Y+LM+ CW + RP+F ++ IL+ + E+ +G
Sbjct 831 YNLMRLCWSKLPADRPSFCSIHRILQRMCERAEGTV 866
Score = 245 bits (625), Expect = 2e-66, Method: Composition-based stats.
Identities = 71/317 (22%), Positives = 127/317 (40%), Gaps = 60/317 (19%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ I + +G+G V++ R +P V +K+L
Sbjct 570 PRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTM-------------------VAVKML 610
Query 645 DPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--- 700
D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+ +LR
Sbjct 611 KEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMS 670
Query 701 ------------------RERGHVPMA--WKMVVAQQLASALSYLENKNLVHGNVCGRNI 740
G P++ ++ +A+Q+A+ ++YL + VH ++ RN
Sbjct 671 PHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNC 730
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLSTA 794
L+ G + +K++D G+ S + I W+ PE + N +T
Sbjct 731 LV-------GENMVVKIADFGLSRNIYSADYYKADGNDAIPIRWMPPESIF--YNRYTTE 781
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYE 852
D W +G L EI G P + E ++ + + L PE +L L C +
Sbjct 782 SDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILACPENCPLELYNLMRLCWSKL 841
Query 853 PTQRPSFRTILRDLTRL 869
P RPSF +I R L R+
Sbjct 842 PADRPSFCSIHRILQRM 858
>sp|Q8GYA4|CRK10_ARATH Cysteine-rich receptor-like protein kinase
10 OS=Arabidopsis thaliana OX=3702 GN=CRK10 PE=1 SV=3
Length=669
Score = 261 bits (666), Expect = 2e-73, Method: Composition-based stats.
Identities = 74/294 (25%), Positives = 119/294 (40%), Gaps = 17/294 (6%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
+ +G+G FG+V G VAVK L G +K
Sbjct 337 DYRTIQTATDDFVESNKIGQGGFGEVYKGTL-----SDGTEVAVKRLSKSSGQGEVE-FK 390
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLL 1001
E+ ++ L H ++++ G C D E+ LV EYVP SL +L + + +
Sbjct 391 NEVVLVAKLQHRNLVRLLGFCLDGEER--VLVYEYVPNKSLDYFLFDPAKKGQLDWTRRY 448
Query 1002 LFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
+ G+ YLH IHRDL A N+LLD D KI DFG+A+
Sbjct 449 KIIGGVARGILYLHQDSRLTIIHRDLKASNILLDADMNPKIADFGMARIFGLDQTEENTS 508
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQG 1117
+ +PE ++ SDV+SFGV + E+++ +SS +L+ A G
Sbjct 509 R-IVGTYGYMSPEYAMHGQYSMKSDVYSFGVLVLEIISGKKNSSFYQTDGAHDLVSYAWG 567
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ R EL++ H+ C + + + RPT ++ +L +
Sbjct 568 LWSNGRPLELVDPAIVENCQRNEVVRCVHIGLLCVQEDPAERPTLSTIVLMLTS 621
Score = 238 bits (607), Expect = 2e-65, Method: Composition-based stats.
Identities = 66/351 (19%), Positives = 121/351 (34%), Gaps = 64/351 (18%)
Query 545 FSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTRTN 602
F C L + S A T + QL + + + + + +GQG
Sbjct 302 FIAGYCFLTRRARKSYYTPSAFAGDDITTADSLQLDYRTIQTATDDFVESNKIGQGGFGE 361
Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662
VY+G L V +K L S + F L+
Sbjct 362 VYKGTLSDG-------------------------TEVAVKRLSKSSGQGEVEFKNEVVLV 396
Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR--ERGHVPMAWKMVVAQQLAS 720
+++ H +L + G C+ G E ++V EYV + LD +L ++G + + + +A
Sbjct 397 AKLQHRNLVRLLGFCLDGEERVLVYEYVPNKSLDYFLFDPAKKGQLDWTRRYKIIGGVAR 456
Query 721 ALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREE 771
+ YL + ++H ++ NILL K++D G+ +
Sbjct 457 GILYLHQDSRLTIIHRDLKASNILLD-------ADMNPKIADFGMARIFGLDQTEENTSR 509
Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS---PSEKEHFY- 827
V +++PE G S D + FG +LEI + ++ + +
Sbjct 510 IVGTYGYMSPEYAMHG--QYSMKSDVYSFGVLVLEIISGKKNSSFYQTDGAHDLVSYAWG 567
Query 828 -QRQHRLPEPSCPQLAT------------LTSQCLTYEPTQRPSFRTILRD 865
R E P + + C+ +P +RP+ TI+
Sbjct 568 LWSNGRPLELVDPAIVENCQRNEVVRCVHIGLLCVQEDPAERPTLSTIVLM 618
>sp|Q9M0X5|CRK25_ARATH Cysteine-rich receptor-like protein kinase
25 OS=Arabidopsis thaliana OX=3702 GN=CRK25 PE=3 SV=1
Length=675
Score = 261 bits (666), Expect = 3e-73, Method: Composition-based stats.
Identities = 80/280 (29%), Positives = 121/280 (43%), Gaps = 17/280 (6%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG G FG+V TGE VA+K L Q +K E+D++ L H ++
Sbjct 351 NKLGHGGFGEVYKGQL-----ITGETVAIKRLSQGST-QGAEEFKNEVDVVAKLQHRNLA 404
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016
K G C D EK LV E+VP SL +L R + + + I G+ YLH
Sbjct 405 KLLGYCLDGEEK--ILVYEFVPNKSLDYFLFDNEKRRVLDWQRRYKIIEGIARGILYLHR 462
Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRDL A N+LLD D KI DFG+A+ + + +PE
Sbjct 463 DSRLTIIHRDLKASNILLDADMHPKISDFGMARIFGVDQTQANTKR-IVGTYGYMSPEYA 521
Query 1074 KEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
K+ SDV+SFGV + EL+T +SS +L+ EL++
Sbjct 522 IHGKYSVKSDVYSFGVLVLELITGKKNSSFYEEDGLGDLVTYVWKLWVENSPLELVDEAM 581
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
R H+ C + ++S RP+ ++++ ++ +
Sbjct 582 RGNFQTNEVIRCIHIALLCVQEDSSERPSMDDILVMMNSF 621
Score = 251 bits (640), Expect = 9e-70, Method: Composition-based stats.
Identities = 76/382 (20%), Positives = 135/382 (35%), Gaps = 69/382 (18%)
Query 517 EGWGRSFPSV-RELGAALQGCLLRAGDDCFSL-RRCCLPQPGETSNLIIMRGARASPRTL 574
+G G++ + + + C+L G C+ L RR ET +L S TL
Sbjct 276 KGKGKNLTVIVTAIAVPVSVCVLLLGAMCWLLARRRNNKLSAETEDL--DEDGITSTETL 333
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
Q S + ++ + LG G VY+G+L +
Sbjct 334 QF-QFSAIEAATNKFSESNKLGHGGFGEVYKGQLITGET--------------------- 371
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
V +K L A F +++++ H +LA + G C+ G E I+V E+V +
Sbjct 372 ----VAIKRLSQGSTQGAEEFKNEVDVVAKLQHRNLAKLLGYCLDGEEKILVYEFVPNKS 427
Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAE 749
LD +L + W + + + +A + YL + ++H ++ NILL
Sbjct 428 LDYFLFDNEKRRVLDWQRRYKIIEGIARGILYLHRDSRLTIIHRDLKASNILLD------ 481
Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
K+SD G+ + + V +++PE G S D + FG
Sbjct 482 -ADMHPKISDFGMARIFGVDQTQANTKRIVGTYGYMSPEYAIHG--KYSVKSDVYSFGVL 538
Query 804 LLEICFDGEAP------------------LQSRSPSEKEHFYQRQHRLPEPSCPQLATLT 845
+LE+ + SP E R + + +
Sbjct 539 VLELITGKKNSSFYEEDGLGDLVTYVWKLWVENSPLELVDEAMRGNFQTNEVIRCIH-IA 597
Query 846 SQCLTYEPTQRPSFRTILRDLT 867
C+ + ++RPS IL +
Sbjct 598 LLCVQEDSSERPSMDDILVMMN 619
>sp|Q07E24|MET_MUSPF Hepatocyte growth factor receptor OS=Mustela
putorius furo OX=9669 GN=MET PE=3 SV=1
Length=1382
Score = 271 bits (693), Expect = 3e-73, Method: Composition-based stats.
Identities = 89/285 (31%), Positives = 136/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V ND AVK+L S + E I++ H
Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348
Score = 229 bits (583), Expect = 1e-59, Method: Composition-based stats.
Identities = 63/328 (19%), Positives = 120/328 (37%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L +++ +K L+
Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1119
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D+ +G
Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDIIDG 1378
>sp|Q9ZQ31|STY13_ARATH Serine/threonine-protein kinase STY13 OS=Arabidopsis
thaliana OX=3702 GN=STY13 PE=1 SV=2
Length=411
Score = 253 bits (645), Expect = 3e-73, Method: Composition-based stats.
Identities = 80/314 (25%), Positives = 129/314 (41%), Gaps = 34/314 (11%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-- 932
D D R L +G FGK+ Y GE VA+K L
Sbjct 108 MDTRYPTEGLTNYDEWTIDLRKLNMGPAFAQGAFGKLYKGTY------NGEDVAIKILER 161
Query 933 ---KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
+ ++QE+ +L L H +I+++ G C +V EY GS+R +
Sbjct 162 PENSPEKAQFMEQQFQQEVSMLANLKHPNIVRFIGACRKPM--VWCIVTEYAKGGSVRQF 219
Query 990 LPRH---SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
L R ++ L + A + GMAY+H +++IHRDL + N+L+ D+ +KI DFG+A+
Sbjct 220 LTRRQNRAVPLKLAVKQALDVARGMAYVHGRNFIHRDLKSDNLLISADKSIKIADFGVAR 279
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
+ W APE ++ + DV+SFG+ L+EL+T
Sbjct 280 IEVQTEG----MTPETGTYRWMAPEMIQHRAYNQKVDVYSFGIVLWELITGLLPF----- 330
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
Q V ++ RG R P+ C + +M CW+ RP F ++
Sbjct 331 ---------QNMTAVQAAFAVVNRGVRPTVPNDCLPVLSDIMTRCWDANPEVRPCFVEVV 381
Query 1167 PILKTVHEKYQGQA 1180
+L+ + A
Sbjct 382 KLLEAAETEIMTTA 395
Score = 216 bits (549), Expect = 4e-60, Method: Composition-based stats.
Identities = 60/303 (20%), Positives = 116/303 (38%), Gaps = 49/303 (16%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
T L+ +D +++ QG +Y+G E
Sbjct 114 TEGLTNYDEWTIDLRKLNMGPAFAQGAFGKLYKGTYNGED-------------------- 153
Query 633 RGQELRVVLKVLDPSHHDIALAFYET------ASLMSQVSHTHLAFVHGVCVRGPENIMV 686
V +K+L+ + A + S+++ + H ++ G C + +V
Sbjct 154 ------VAIKILERPENSPEKAQFMEQQFQQEVSMLANLKHPNIVRFIGACRKPMVWCIV 207
Query 687 TEYVEHGPLDVWL-RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
TEY + G + +L RR+ VP+ + A +A ++Y+ +N +H ++ N+L++
Sbjct 208 TEYAKGGSVRQFLTRRQNRAVPLKLAVKQALDVARGMAYVHGRNFIHRDLKSDNLLIS-- 265
Query 746 GLAEGTSPFIKLSDPGVGLGALSREER---VERIPWLAPECLPGGANSLSTAMDKWGFGA 802
IK++D GV + E W+APE + A + +D + FG
Sbjct 266 -----ADKSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRA--YNQKVDVYSFGI 318
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQR---QHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859
L E+ G P Q+ + + + +P P L+ + ++C P RP F
Sbjct 319 VLWELI-TGLLPFQNMTAVQAAFAVVNRGVRPTVPNDCLPVLSDIMTRCWDANPEVRPCF 377
Query 860 RTI 862
+
Sbjct 378 VEV 380
>sp|Q75ZY9|MET_CANLF Hepatocyte growth factor receptor OS=Canis
lupus familiaris OX=9615 GN=MET PE=1 SV=1
Length=1382
Score = 271 bits (692), Expect = 3e-73, Method: Composition-based stats.
Identities = 89/285 (31%), Positives = 135/285 (47%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V ND AVK+L S + E I++ H
Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW A RP+F L+ + + + G+
Sbjct 1304 LQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGE 1348
Score = 227 bits (579), Expect = 3e-59, Method: Composition-based stats.
Identities = 63/328 (19%), Positives = 118/328 (36%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L +++ +K L+
Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1119
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C RPSF ++ ++ + + +
Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D +G
Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNIDG 1378
>sp|O49564|CRK27_ARATH Cysteine-rich receptor-like protein kinase
27 OS=Arabidopsis thaliana OX=3702 GN=CRK27 PE=3 SV=2
Length=642
Score = 260 bits (664), Expect = 3e-73, Method: Composition-based stats.
Identities = 77/321 (24%), Positives = 132/321 (41%), Gaps = 16/321 (5%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
L+ + + + + + +GEG FG V + G +A
Sbjct 305 LKENAENEFESTDSLHFDFETIRVATDDFSLTNKIGEGGFGVVYKG-----HLPDGLEIA 359
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
VK L G Q + +K E+ ++ L H++++K G + E+ LV E++P SL
Sbjct 360 VKRLSIHSG-QGNAEFKTEVLLMTKLQHKNLVKLFGFSIKESER--LLVYEFIPNTSLDR 416
Query 989 YL----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGD 1041
+L + + + + G+ YLH IHRDL + NVLLD L KI D
Sbjct 417 FLFDPIKQKQLDWEKRYNIIVGVSRGLLYLHEGSEFPIIHRDLKSSNVLLDEQMLPKISD 476
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FG+A+ + R + APE +F +DV+SFGV + E++T +S
Sbjct 477 FGMARQFDFDNTQAVTRR-VVGTYGYMAPEYAMHGRFSVKTDVYSFGVLVLEIITGKRNS 535
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ +L A EL++ K + + +C + + RPT
Sbjct 536 GLGLGEGTDLPTFAWQNWIEGTSMELIDPVLLQTHDKKESMQCLEIALSCVQENPTKRPT 595
Query 1162 FENLIPILKTVHEKYQGQAPS 1182
++++ +L + E Q PS
Sbjct 596 MDSVVSMLSSDSESRQLPKPS 616
Score = 225 bits (574), Expect = 3e-61, Method: Composition-based stats.
Identities = 66/390 (17%), Positives = 126/390 (32%), Gaps = 63/390 (16%)
Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562
+K P+ + G+S + L A+ + F + + +
Sbjct 249 QKQPLSSHNNNTRRSDQGKSKDRSKTLIFAVVPIVAIILGLVFLFIY-LKRRRKKKTLKE 307
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
S +L+ RV + + + +G+G VY+G L
Sbjct 308 NAENEFESTDSLHF-DFETIRVATDDFSLTNKIGEGGFGVVYKGHLPDG----------- 355
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
L + +K L F LM+++ H +L + G ++ E
Sbjct 356 --------------LEIAVKRLSIHSGQGNAEFKTEVLLMTKLQHKNLVKLFGFSIKESE 401
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCG 737
++V E++ + LD +L + W + + ++ L YL + ++H ++
Sbjct 402 RLLVYEFIPNTSLDRFLFDPIKQKQLDWEKRYNIIVGVSRGLLYLHEGSEFPIIHRDLKS 461
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSL 791
N+LL L K+SD G+ + V ++APE G
Sbjct 462 SNVLLDEQMLP-------KISDFGMARQFDFDNTQAVTRRVVGTYGYMAPEYAMHG--RF 512
Query 792 STAMDKWGFGATLLEICFDGE-----------APLQSRSPS-EKEHFYQRQHRLPEPS-- 837
S D + FG +LEI P + E L +
Sbjct 513 SVKTDVYSFGVLVLEIITGKRNSGLGLGEGTDLPTFAWQNWIEGTSMELIDPVLLQTHDK 572
Query 838 --CPQLATLTSQCLTYEPTQRPSFRTILRD 865
Q + C+ PT+RP+ +++
Sbjct 573 KESMQCLEIALSCVQENPTKRPTMDSVVSM 602
>sp|Q2QLA9|MET_HORSE Hepatocyte growth factor receptor OS=Equus
caballus OX=9796 GN=MET PE=3 SV=1
Length=1381
Score = 271 bits (692), Expect = 3e-73, Method: Composition-based stats.
Identities = 89/285 (31%), Positives = 136/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V ND AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1256
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1303 LQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1347
Score = 228 bits (580), Expect = 2e-59, Method: Composition-based stats.
Identities = 63/328 (19%), Positives = 119/328 (36%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L +++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D +G
Sbjct 1350 VHVNATYVNVKCVAPYPSLLSSQDNVDG 1377
>sp|Q54RB7|SHKA_DICDI Dual specificity protein kinase shkA OS=Dictyostelium
discoideum OX=44689 GN=shkA PE=2 SV=1
Length=527
Score = 256 bits (655), Expect = 4e-73, Method: Composition-based stats.
Identities = 69/274 (25%), Positives = 124/274 (45%), Gaps = 25/274 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V + VAVK + + + +++E+ I+ ++H +I+ +
Sbjct 51 LGDGSFGTVYKGRCRLKD------VAVKVMLKQVDQKTLTDFRKEVAIMSKIFHPNIVLF 104
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH-- 1018
G C L + E + G+L L P + L + A+ G+ +LH+ +
Sbjct 105 LGACTS-TPGKLMICTELM-KGNLESLLLDPMVKLPLITRMRMAKDAALGVLWLHSSNPV 162
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+IHRDL N+L+D + VK+ DFGL++ G ++ W APE L+ F
Sbjct 163 FIHRDLKTSNLLVDANLTVKVCDFGLSQIKQRGENLKDGQDGAKGTPLWMAPEVLQGRLF 222
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+DV+SFG+ L+++ T + + + + E+ R PD
Sbjct 223 NEKADVYSFGLVLWQIFTRQELF-------------PEFDNFFKFVAAICEKQLRPSIPD 269
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
CP + L++ CW+ RP+FE ++ L+ +
Sbjct 270 DCPKSLKELIQKCWDPNPEVRPSFEGIVSELEEI 303
Score = 228 bits (582), Expect = 2e-63, Method: Composition-based stats.
Identities = 66/338 (20%), Positives = 117/338 (35%), Gaps = 50/338 (15%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ + EIT S LG G+ VY+GR R++ V +
Sbjct 38 PEISETEITTESILGDGSFGTVYKGRCRLKD--------------------------VAV 71
Query 642 K-VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV-RGPENIMVTEYVEHGPLDVWL 699
K +L F + ++MS++ H ++ G C + ++ TE ++ G L+ L
Sbjct 72 KVMLKQVDQKTLTDFRKEVAIMSKIFHPNIVLFLGACTSTPGKLMICTELMK-GNLESLL 130
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKL 757
+P+ +M +A+ A + +L + N +H ++ N+L+ + +K+
Sbjct 131 LDPMVKLPLITRMRMAKDAALGVLWLHSSNPVFIHRDLKTSNLLVD-------ANLTVKV 183
Query 758 SDPGVGLGALSREE-------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
D G+ E W+APE L G + D + FG L +I
Sbjct 184 CDFGLSQIKQRGENLKDGQDGAKGTPLWMAPEVLQGRL--FNEKADVYSFGLVLWQIFTR 241
Query 811 GE-APLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
E P ++Q R +P+ L L +C P RPSF I+ +L
Sbjct 242 QELFPEFDNFFKFVAAICEKQLRPSIPDDCPKSLKELIQKCWDPNPEVRPSFEGIVSELE 301
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
+ + I
Sbjct 302 EIIIDCCIPDEYGAILWKNHFKHENEANWKDFINVFSN 339
Score = 38.1 bits (87), Expect = 0.58, Method: Composition-based stats.
Identities = 12/64 (19%), Positives = 27/64 (42%), Gaps = 2/64 (3%)
Query 450 GIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLR-KFPI 507
HG + + +LR + +G +L+ +STS ++ ++ + R + KF +
Sbjct 424 WFHGDISTSESENRLRQKPEGTFLVRFSTSEYGAYTISKVSKNGGISHQRIHRPQGKFQV 483
Query 508 EQQD 511
Sbjct 484 NNSK 487
>sp|F4JEQ2|PBL23_ARATH Probable serine/threonine-protein kinase
PBL23 OS=Arabidopsis thaliana OX=3702 GN=PBL23 PE=2 SV=1
Length=386
Score = 251 bits (642), Expect = 4e-73, Method: Composition-based stats.
Identities = 80/301 (27%), Positives = 126/301 (42%), Gaps = 19/301 (6%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
+ LGEG FG+V + ++VAVK L + G Q
Sbjct 68 HIFTFRELCVATKNFNPDNQLGEGGFGRVYKGQIETPE----QVVAVKQLDRN-GYQGNR 122
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIG 996
+ E+ +L L+H++++ G C D ++ LV EY+ GSL D+L + +
Sbjct 123 EFLVEVMMLSLLHHQNLVNLVGYCADGDQR--ILVYEYMQNGSLEDHLLELARNKKKPLD 180
Query 997 LAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ A G+ YLH I+RD A N+LLD + K+ DFGLAK P G E
Sbjct 181 WDTRMKVAAGAARGLEYLHETADPPVIYRDFKASNILLDEEFNPKLSDFGLAKVGPTGGE 240
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELI 1112
+ V + APE + SDV+SFGV E++T + PT+ L+
Sbjct 241 TH-VSTRVMGTYGYCAPEYALTGQLTVKSDVYSFGVVFLEMITGRRVIDTTKPTEEQNLV 299
Query 1113 GIAQGQMTVLR-LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
A R T + + P K + + C + EA+ RP +++ L+
Sbjct 300 TWASPLFKDRRKFTLMADPLLEGKYPIKGLYQALAVAAMCLQEEAATRPMMSDVVTALEY 359
Query 1172 V 1172
+
Sbjct 360 L 360
Score = 231 bits (589), Expect = 8e-66, Method: Composition-based stats.
Identities = 69/318 (22%), Positives = 113/318 (36%), Gaps = 66/318 (21%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V K + LG+G VY+G++ E V +K
Sbjct 77 VATKNFNPDNQLGEGGFGRVYKGQIETP------------------------EQVVAVKQ 112
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---- 699
LD + + F ++S + H +L + G C G + I+V EY+++G L+ L
Sbjct 113 LDRNGYQGNREFLVEVMMLSLLHHQNLVNLVGYCADGDQRILVYEYMQNGSLEDHLLELA 172
Query 700 RRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIK 756
R ++ + +M VA A L YL +++ + NILL K
Sbjct 173 RNKKKPLDWDTRMKVAAGAARGLEYLHETADPPVIYRDFKASNILLDEEFNP-------K 225
Query 757 LSDPGVGL-GALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
LSD G+ G E V + APE G L+ D + FG LE+
Sbjct 226 LSDFGLAKVGPTGGETHVSTRVMGTYGYCAPEYALTG--QLTVKSDVYSFGVVFLEMI-T 282
Query 811 GEAPLQSRSPSEKEHFYQR-------------------QHRLPEPSCPQLATLTSQCLTY 851
G + + P+E+++ + + P Q + + CL
Sbjct 283 GRRVIDTTKPTEEQNLVTWASPLFKDRRKFTLMADPLLEGKYPIKGLYQALAVAAMCLQE 342
Query 852 EPTQRPSFRTILRDLTRL 869
E RP ++ L L
Sbjct 343 EAATRPMMSDVVTALEYL 360
>sp|Q769I5|MET_BOVIN Hepatocyte growth factor receptor OS=Bos
taurus OX=9913 GN=MET PE=2 SV=1
Length=1384
Score = 271 bits (692), Expect = 4e-73, Method: Composition-based stats.
Identities = 90/285 (32%), Positives = 136/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V ND AVK+L S + E I++ H
Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLA 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ V + Y + PV W A E L+
Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQ 1257
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISVIFSTFIGE 1348
Score = 229 bits (583), Expect = 9e-60, Method: Composition-based stats.
Identities = 63/328 (19%), Positives = 118/328 (36%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L +++ +K L+
Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1119
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMEYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDVYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISVIFSTFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D G
Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNVSG 1378
>sp|Q2QLE0|MET_PIG Hepatocyte growth factor receptor OS=Sus scrofa
OX=9823 GN=MET PE=2 SV=1
Length=1381
Score = 270 bits (691), Expect = 4e-73, Method: Composition-based stats.
Identities = 90/285 (32%), Positives = 135/285 (47%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V ND AVK+L S + E I++ H
Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ V + Y + PV W A E L+
Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQ 1256
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW A RP+F L+ + + + G+
Sbjct 1303 LQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGE 1347
Score = 228 bits (580), Expect = 2e-59, Method: Composition-based stats.
Identities = 63/328 (19%), Positives = 118/328 (36%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L +++ +K L+
Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1118
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDVYD 1231
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C RPSF ++ ++ + + +
Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGEHY 1349
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D +G
Sbjct 1350 VHVNATYVNVKCVAPYPSLLSSQDNVDG 1377
>sp|Q09YI9|MET_SHEEP Hepatocyte growth factor receptor OS=Ovis
aries OX=9940 GN=MET PE=3 SV=1
Length=1384
Score = 270 bits (691), Expect = 5e-73, Method: Composition-based stats.
Identities = 90/285 (32%), Positives = 136/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V ND AVK+L S + E I++ H
Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLA 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ V + Y + PV W A E L+
Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQ 1257
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRIAAIFSAFIGE 1348
Score = 228 bits (582), Expect = 1e-59, Method: Composition-based stats.
Identities = 62/328 (19%), Positives = 117/328 (36%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L +++ +K L+
Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1119
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMEYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDVYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ + + + +
Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRIAAIFSAFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L ++ G
Sbjct 1351 VHVNATYVNVRCVAPYPSLLSSQENVSG 1378
>sp|O49839|PBL2_ARATH Probable serine/threonine-protein kinase
PBL2 OS=Arabidopsis thaliana OX=3702 GN=PBL2 PE=1 SV=1
Length=426
Score = 253 bits (645), Expect = 5e-73, Method: Composition-based stats.
Identities = 87/283 (31%), Positives = 129/283 (46%), Gaps = 16/283 (6%)
Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
LGEG FG V D + G+G +VAVK LK + G Q W E++ L L H
Sbjct 92 LGEGGFGCVFKGWIDQTSLTASRPGSGIVVAVKQLKPE-GFQGHKEWLTEVNYLGQLSHP 150
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYL 1014
+++ G C + GE L LV E++P GSL ++L R + A + A +G+ +L
Sbjct 151 NLVLLVGYCAE-GENRL-LVYEFMPKGSLENHLFRRGAQPLTWAIRMKVAVGAAKGLTFL 208
Query 1015 HAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
H I+RD A N+LLD D K+ DFGLAKA P G + V + APE
Sbjct 209 HEAKSQVIYRDFKAANILLDADFNAKLSDFGLAKAGPTGDNTH-VSTKVIGTHGYAAPEY 267
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQM-TVLRLTELLER 1130
+ + SDV+SFGV L EL++ + S L+ A + +L +++
Sbjct 268 VATGRLTAKSDVYSFGVVLLELISGRRAMDNSNGGNEYSLVDWATPYLGDKRKLFRIMDT 327
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
P K +L C +A RP ++ L+ +
Sbjct 328 KLGGQYPQKGAFTAANLALQCLNPDAKLRPKMSEVLVTLEQLE 370
Score = 239 bits (611), Expect = 2e-68, Method: Composition-based stats.
Identities = 79/359 (22%), Positives = 128/359 (36%), Gaps = 55/359 (15%)
Query 561 LIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618
L +R + NL +F+ + K Q + LG+G V++G +
Sbjct 56 LPTLRTEGEILSSPNLKAFTFNELKNATKNFRQDNLLGEGGFGCVFKGWI---------- 105
Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678
D+ L R G + V +K L P + + + Q+SH +L + G C
Sbjct 106 ----DQTSLTASRP-GSGIVVAVKQLKPEGFQGHKEWLTEVNYLGQLSHPNLVLLVGYCA 160
Query 679 RGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN--KNLVHGN 734
G ++V E++ G L+ L R RG P+ W +M VA A L++L +++ +
Sbjct 161 EGENRLLVYEFMPKGSLENHLFR-RGAQPLTWAIRMKVAVGAAKGLTFLHEAKSQVIYRD 219
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGA 788
NILL KLSD G+ + + + + APE + G
Sbjct 220 FKAANILLD-------ADFNAKLSDFGLAKAGPTGDNTHVSTKVIGTHGYAAPEYVATG- 271
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR------------------Q 830
L+ D + FG LLE+ A S +E
Sbjct 272 -RLTAKSDVYSFGVVLLELISGRRAMDNSNGGNEYSLVDWATPYLGDKRKLFRIMDTKLG 330
Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
+ P+ A L QCL + RP +L L +L+ +SP
Sbjct 331 GQYPQKGAFTAANLALQCLNPDAKLRPKMSEVLVTLEQLESVAKPGTKHTQMESPRFHH 389
>sp|Q07E37|MET_NEONE Hepatocyte growth factor receptor OS=Neofelis
nebulosa OX=61452 GN=MET PE=3 SV=1
Length=1382
Score = 270 bits (690), Expect = 5e-73, Method: Composition-based stats.
Identities = 88/285 (31%), Positives = 137/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V ++D AVK+L S + E I++ H
Sbjct 1080 HFNEVIGRGHFGCVYHGTLLDSDDK-KIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348
Score = 226 bits (577), Expect = 4e-59, Method: Composition-based stats.
Identities = 63/328 (19%), Positives = 119/328 (36%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L +++ +K L+
Sbjct 1081 FNEVIGRGHFGCVYHGTLLDSD---------------------DKKIHCAVKSLNRITDI 1119
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D +G
Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNIDG 1378
>sp|A0M8S8|MET_FELCA Hepatocyte growth factor receptor OS=Felis
catus OX=9685 GN=MET PE=3 SV=1
Length=1382
Score = 270 bits (690), Expect = 5e-73, Method: Composition-based stats.
Identities = 88/285 (31%), Positives = 137/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V ++D AVK+L S + E I++ H
Sbjct 1080 HFNEVIGRGHFGCVYHGTLLDSDDK-KIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348
Score = 226 bits (577), Expect = 4e-59, Method: Composition-based stats.
Identities = 63/328 (19%), Positives = 119/328 (36%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L +++ +K L+
Sbjct 1081 FNEVIGRGHFGCVYHGTLLDSD---------------------DKKIHCAVKSLNRITDI 1119
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D +G
Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNIDG 1378
>sp|A1X150|MET_ECHTE Hepatocyte growth factor receptor OS=Echinops
telfairi OX=9371 GN=MET PE=3 SV=1
Length=1380
Score = 270 bits (690), Expect = 5e-73, Method: Composition-based stats.
Identities = 93/286 (33%), Positives = 139/286 (49%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V ND AVK+L S + E I++ H
Sbjct 1078 HFNEVIGRGHFGCVYHGTLLD-NDDRKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1136
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ HS + L+ F Q+ +GM YL
Sbjct 1137 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHSPTVKDLIGFGLQVAKGMKYLA 1195
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073
++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L
Sbjct 1196 SKKFVHRDLAARNCMLDGKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1254
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV L+EL+T + +T L +G R
Sbjct 1255 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1300
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1301 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFTELVSRISAIFSTFIGE 1346
Score = 227 bits (578), Expect = 4e-59, Method: Composition-based stats.
Identities = 63/328 (19%), Positives = 117/328 (36%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L +++ +K L+
Sbjct 1079 FNEVIGRGHFGCVYHGTLLDND---------------------DRKIHCAVKSLNRITDI 1117
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E +
Sbjct 1118 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHSPTV 1177
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1178 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLD-------GKFTVKVADFGLARDMYD 1230
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1231 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1288
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1289 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFTELVSRISAIFSTFIGEHY 1348
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L D +G
Sbjct 1349 VHVNATYVNVKCVAPYPSLLSSHDTVDG 1376
>sp|Q61006|MUSK_MOUSE Muscle, skeletal receptor tyrosine-protein
kinase OS=Mus musculus OX=10090 GN=Musk PE=1 SV=1
Length=868
Score = 264 bits (675), Expect = 6e-73, Method: Composition-based stats.
Identities = 86/336 (26%), Positives = 149/336 (44%), Gaps = 43/336 (13%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND-GTGEMVAV 929
N +P + + ++ +RD+GEG FG+V MVAV
Sbjct 548 HPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAV 607
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K LK + ++ +++E ++ + +I+K G C K + L+ EY+ G L ++
Sbjct 608 KMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEF 665
Query 990 LPR-------------------------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDL 1024
L + A+ L A+Q+ GMAYL + ++HRDL
Sbjct 666 LRSMSPHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDL 725
Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084
A RN L+ +VKI DFGL++ + +YY+ + P+ W PE + ++ SDV
Sbjct 726 ATRNCLVGETMVVKIADFGLSRNIY-SADYYKADGNDAIPIRWMPPESIFYNRYTTESDV 784
Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144
W++GV L+E+ ++ M + + G L P+ CP E+
Sbjct 785 WAYGVVLWEIFSYGLQ--------------PYYGMAHEEVIYYVRDGNILACPENCPLEL 830
Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180
Y+LM+ CW + RP+F ++ IL+ + E+ +G
Sbjct 831 YNLMRLCWSKLPADRPSFCSIHRILQRMCERAEGTV 866
Score = 244 bits (623), Expect = 4e-66, Method: Composition-based stats.
Identities = 71/317 (22%), Positives = 127/317 (40%), Gaps = 60/317 (19%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ I + +G+G V++ R +P V +K+L
Sbjct 570 PRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTM-------------------VAVKML 610
Query 645 DPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--- 700
D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+ +LR
Sbjct 611 KEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMS 670
Query 701 ------------------RERGHVPMA--WKMVVAQQLASALSYLENKNLVHGNVCGRNI 740
G P++ ++ +A+Q+A+ ++YL + VH ++ RN
Sbjct 671 PHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNC 730
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLSTA 794
L+ G + +K++D G+ S + I W+ PE + N +T
Sbjct 731 LV-------GETMVVKIADFGLSRNIYSADYYKADGNDAIPIRWMPPESIF--YNRYTTE 781
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYE 852
D W +G L EI G P + E ++ + + L PE +L L C +
Sbjct 782 SDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILACPENCPLELYNLMRLCWSKL 841
Query 853 PTQRPSFRTILRDLTRL 869
P RPSF +I R L R+
Sbjct 842 PADRPSFCSIHRILQRM 858
>sp|Q05688|IGF1R_BOVIN Insulin-like growth factor 1 receptor (Fragment)
OS=Bos taurus OX=9913 GN=IGF1R PE=2 SV=1
Length=640
Score = 259 bits (662), Expect = 6e-73, Method: Composition-based stats.
Identities = 92/312 (29%), Positives = 144/312 (46%), Gaps = 29/312 (9%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALK 933
D D + + R+LG+G FG V E VA+K +
Sbjct 250 NPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVN 309
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR- 992
+ R + E +++ H+++ G QG+ +L ++ME + G L+ YL
Sbjct 310 EAASMRERIEFLNEASVMKEFNCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSL 367
Query 993 ----------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
L++++ A +I +GMAYL+A ++HRDLAARN ++ D VKIGDF
Sbjct 368 RPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDF 427
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
G+ + + E +YYR G PV W +PE LK+ F SDVWSFGV L+E+ T
Sbjct 428 GMTRDIYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIAT------ 480
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
L ++ ++ + G L +PD CP ++ LM+ CW+ RP+F
Sbjct 481 --------LAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSF 532
Query 1163 ENLIPILKTVHE 1174
+I +K E
Sbjct 533 LEIISSVKDEME 544
Score = 253 bits (647), Expect = 6e-71, Method: Composition-based stats.
Identities = 100/530 (19%), Positives = 181/530 (34%), Gaps = 87/530 (16%)
Query 425 RLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLI 484
+L +S+++ P D I GP+ RPE+ ++L +P LI
Sbjct 85 KLGCSASNFVFARTMPA----EGADDIPGPVTWE-----PRPENSIFLKWPEPENPNGLI 135
Query 485 LTVAQR-SQAPDGMQSL----RLRKFPIEQQD-----------GAFVLEGWGR------- 521
L + + + RK+ + + A L G G
Sbjct 136 LMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFF 195
Query 522 ------SFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLN 575
++ + L AL +L + + + + A +P +
Sbjct 196 YVQAKTTYENFIHLMIALPIAVLLIVGGLVIMLYVFHRKRNSSRLGNGVLYASVNPEYFS 255
Query 576 LSQL---SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
+ + V +++IT LGQG+ VYEG + +P
Sbjct 256 AADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEP---------------- 299
Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
E RV +K ++ + + F AS+M + + H+ + GV +G +++ E +
Sbjct 300 ---ETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMT 356
Query 692 HGPLDVWLRRERGHV---------PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
G L +LR R + ++ + +A ++A ++YL VH ++ RN ++
Sbjct 357 RGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV 416
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMD 796
A +K+ D G+ + + + W++PE L G +T D
Sbjct 417 AE-------DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTHSD 467
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854
W FG L EI E P Q S + F L P+ L L C Y P
Sbjct 468 VWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPK 527
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
RPSF I+ + +V + + + +
Sbjct 528 MRPSFLEIISSVKDEMEAGFREVSFYYSEENKPPEPEELDLEPENMESVP 577
>sp|Q9FGB1|CBC2_ARATH Serine/threonine-protein kinase 52 OS=Arabidopsis
thaliana OX=3702 GN=CBC2 PE=1 SV=1
Length=385
Score = 251 bits (641), Expect = 6e-73, Method: Composition-based stats.
Identities = 82/318 (26%), Positives = 131/318 (41%), Gaps = 52/318 (16%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--------- 940
L L G FG V YD G+ VAVK L D G +
Sbjct 75 WEIDPSKLIIKTVLARGTFGTVHRGIYD------GQDVAVKLL--DWGEEGHRSEAEIVS 126
Query 941 -RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL--------------QLVMEYVPLGS 985
R+ + QE+ + L H ++ K+ G L +V+EY+P G+
Sbjct 127 LRADFAQEVAVWHKLDHPNVTKFIGATMGASGLQLQTESGPLAMPNNICCVVVEYLPGGA 186
Query 986 LRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
L+ YL R + ++ A + G++YLH+Q +HRD+ N+LLD R VKI DF
Sbjct 187 LKSYLIKNRRRKLTFKIVVQLALDLARGLSYLHSQKIVHRDVKTENMLLDKTRTVKIADF 246
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
G+A+ + + APE L + DV+SFG+ L+E+ +C
Sbjct 247 GVARVEASNPND---MTGETGTLGYMAPEVLNGNPYNRKCDVYSFGICLWEI--YCCDMP 301
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
P F E+ + ++ + R P CP + +MK CW+ RP
Sbjct 302 YPDLTFSEV------------TSAVVRQNLRPDIPRCCPSALAAVMKRCWDANPDKRPEM 349
Query 1163 ENLIPILKTVHEKYQGQA 1180
+ ++P+L+++ G
Sbjct 350 DEVVPMLESIDTTKGGGM 367
Score = 212 bits (539), Expect = 4e-59, Method: Composition-based stats.
Identities = 76/397 (19%), Positives = 136/397 (34%), Gaps = 76/397 (19%)
Query 530 GAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSF-------H 582
+L L R +L + +T+ + I A +SP TLN
Sbjct 16 LKSLDEQLERHLSRALTLEKNKKKDEEDTTAVAIGGSASSSPVTLNGGGFVGKRKQRLEW 75
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
+D ++ + L +GT V+ G + G+D V +K
Sbjct 76 EIDPSKLIIKTVLARGTFGTVHRG--------------------IYDGQD------VAVK 109
Query 643 VLDPSHH---------DIALAFYETASLMSQVSHTHLAFVHGVC---------VRGPEN- 683
+LD + F + ++ ++ H ++ G
Sbjct 110 LLDWGEEGHRSEAEIVSLRADFAQEVAVWHKLDHPNVTKFIGATMGASGLQLQTESGPLA 169
Query 684 ------IMVTEYVEHGPLDVWL-RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736
+V EY+ G L +L + R + + +A LA LSYL ++ +VH +V
Sbjct 170 MPNNICCVVVEYLPGGALKSYLIKNRRRKLTFKIVVQLALDLARGLSYLHSQKIVHRDVK 229
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLS 792
N+LL + + +K++D GV + ++APE L G N +
Sbjct 230 TENMLLDK-------TRTVKIADFGVARVEASNPNDMTGETGTLGYMAPEVLNG--NPYN 280
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH---RLPEPSCPQLATLTSQCL 849
D + FG L EI + P + SE RQ+ +P LA + +C
Sbjct 281 RKCDVYSFGICLWEIYCC-DMPYPDLTFSEVTSAVVRQNLRPDIPRCCPSALAAVMKRCW 339
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
P +RP ++ L + ++ +
Sbjct 340 DANPDKRPEMDEVVPMLESIDTTKGGGMIPNDQQQGC 376
>sp|Q14289|FAK2_HUMAN Protein-tyrosine kinase 2-beta OS=Homo sapiens
OX=9606 GN=PTK2B PE=1 SV=2
Length=1009
Score = 266 bits (681), Expect = 6e-73, Method: Composition-based stats.
Identities = 97/278 (35%), Positives = 147/278 (53%), Gaps = 22/278 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG+V Y + G VAVK K DC ++ + E I++ L H HI+K
Sbjct 431 LGEGFFGEVYEGVYTN-HKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKL 489
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHYI 1020
G E E+ ++ME P G L YL R+ L L+L++ QIC+ MAYL + + +
Sbjct 490 IGIIE---EEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCV 546
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+A RN+L+ + VK+GDFGL++ + E +YY+ P+ W +PE + +F
Sbjct 547 HRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKASVT-RLPIKWMSPESINFRRFTT 604
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
ASDVW F V ++E+L+ + + +LE+G+RLP+PD C
Sbjct 605 ASDVWMFAVCMWEILSFGKQ--------------PFFWLENKDVIGVLEKGDRLPKPDLC 650
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P +Y LM CW+ + S RP F L+ L V++ +
Sbjct 651 PPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKD 688
Score = 244 bits (622), Expect = 2e-65, Method: Composition-based stats.
Identities = 72/331 (22%), Positives = 132/331 (40%), Gaps = 39/331 (12%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
A TL + + ++++ LG+G VYEG
Sbjct 403 AEIPDETLRRPGGPQYGIAREDVVLNRILGEGFFGEVYEG-------------------- 442
Query 627 LVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
V +G+++ V +K D F A +M + H H+ + G+ + +
Sbjct 443 -VYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWI 500
Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
+ E +G L +L R + + + ++ + Q+ A++YLE+ N VH ++ RNIL+A
Sbjct 501 IMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVA-- 558
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGF 800
+ +KL D G+ + I W++PE + +TA D W F
Sbjct 559 -----SPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESI--NFRRFTTASDVWMF 611
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPS 858
+ EI G+ P + ++ RLP+P P L TL ++C Y+P+ RP
Sbjct 612 AVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPR 671
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
F ++ L+ + + ++ P
Sbjct 672 FTELVCSLSDVYQMEKDIAMEQERNARYRTP 702
>sp|Q108U6|MET_LOXAF Hepatocyte growth factor receptor OS=Loxodonta
africana OX=9785 GN=MET PE=3 SV=1
Length=1382
Score = 270 bits (689), Expect = 7e-73, Method: Composition-based stats.
Identities = 92/286 (32%), Positives = 138/286 (48%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V N AVK+L S + E I++ H
Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NGDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073
++ ++HRDLAARN +LD VK+ DFGLA+ V + EYY V + PV W A E L
Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESL 1256
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV L+EL+T + +T L +G R
Sbjct 1257 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1302
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L +P+ CP +Y +M CW +A RP+F L+ + + + G+
Sbjct 1303 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348
Score = 230 bits (586), Expect = 4e-60, Method: Composition-based stats.
Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G VY G L G +++ +K L+
Sbjct 1081 FNEVIGRGHFGCVYHGTLLDNG---------------------DKKIHCAVKSLNRITDI 1119
Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDVYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPSF ++ ++ + + +
Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKR 895
+ + V
Sbjct 1351 VHVNTTYVNVKCVAPYP 1367
>sp|Q8GWJ7|CRK19_ARATH Cysteine-rich receptor-like protein kinase
19 OS=Arabidopsis thaliana OX=3702 GN=CRK19 PE=1 SV=2
Length=645
Score = 259 bits (661), Expect = 7e-73, Method: Composition-based stats.
Identities = 77/286 (27%), Positives = 120/286 (42%), Gaps = 18/286 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
I LG+G FG+V +G VAVK L G Q ++ E+ ++ L
Sbjct 324 NCFLPINKLGQGGFGEVYKGTL-----SSGLQVAVKRLSKTSG-QGEKEFENEVVVVAKL 377
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEG 1010
H +++K G C + EK LV E+VP SL +L + + + I G
Sbjct 378 QHRNLVKLLGYCLEGEEK--ILVYEFVPNKSLDHFLFDSTMKMKLDWTRRYKIIGGIARG 435
Query 1011 MAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH IHRDL A N+LLD+D KI DFG+A+ R +
Sbjct 436 ILYLHQDSRLTIIHRDLKAGNILLDDDMNPKIADFGMARIFGMDQTEAMTRR-VVGTYGY 494
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLT 1125
+PE +F SDV+SFGV + E+++ +S L+ + +
Sbjct 495 MSPEYAMYGQFSMKSDVYSFGVLVLEIISGMKNSSLYQMDESVGNLVTYTWRLWSNGSPS 554
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
EL++ H+ C + +A RPT +++ +L T
Sbjct 555 ELVDPSFGDNYQTSEITRCIHIALLCVQEDAEDRPTMSSIVQMLTT 600
Score = 236 bits (602), Expect = 6e-65, Method: Composition-based stats.
Identities = 59/324 (18%), Positives = 110/324 (34%), Gaps = 65/324 (20%)
Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
T Q F ++ ++ LGQG VY+G L
Sbjct 308 TAGSLQFDFKAIEAATNCFLPINKLGQGGFGEVYKGTLSSG------------------- 348
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
L+V +K L + F +++++ H +L + G C+ G E I+V E+V
Sbjct 349 ------LQVAVKRLSKTSGQGEKEFENEVVVVAKLQHRNLVKLLGYCLEGEEKILVYEFV 402
Query 691 EHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745
+ LD +L + + W + + +A + YL + ++H ++ NILL
Sbjct 403 PNKSLDHFLFDSTMKMKLDWTRRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNILLD-- 460
Query 746 GLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWG 799
K++D G+ + V +++PE G S D +
Sbjct 461 -----DDMNPKIADFGMARIFGMDQTEAMTRRVVGTYGYMSPEYAMYG--QFSMKSDVYS 513
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------------QL 841
FG +LEI + + + RL P +
Sbjct 514 FGVLVLEIISGMKNSSLYQMDESVGNLVTYTWRLWSNGSPSELVDPSFGDNYQTSEITRC 573
Query 842 ATLTSQCLTYEPTQRPSFRTILRD 865
+ C+ + RP+ +I++
Sbjct 574 IHIALLCVQEDAEDRPTMSSIVQM 597
>sp|Q9SSA4|CBC1_ARATH Serine/threonine-protein kinase 54 OS=Arabidopsis
thaliana OX=3702 GN=CBC1 PE=1 SV=1
Length=411
Score = 251 bits (642), Expect = 8e-73, Method: Composition-based stats.
Identities = 79/318 (25%), Positives = 131/318 (41%), Gaps = 52/318 (16%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--------- 940
L + G FG V YD G+ VAVK L D G +
Sbjct 101 WEIDPSKLIIKSVIARGTFGTVHRGIYD------GQDVAVKLL--DWGEEGHRSDAEIAS 152
Query 941 -RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL--------------QLVMEYVPLGS 985
R+ + QE+ + L H ++ K+ G E S+ +V+EY P G+
Sbjct 153 LRAAFTQEVAVWHKLDHPNVTKFIGAAMGTSEMSIQTENGQMGMPSNVCCVVVEYCPGGA 212
Query 986 LRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
L+ +L R + ++ + + G++YLH+Q +HRD+ N+LLD R +KI DF
Sbjct 213 LKSFLIKTRRRKLAFKVVIQLSLDLARGLSYLHSQKIVHRDVKTENMLLDKSRTLKIADF 272
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
G+A+ + + APE L + DV+SFG+ L+E+ +C
Sbjct 273 GVARLEASNPND---MTGETGTLGYMAPEVLNGSPYNRKCDVYSFGICLWEI--YCCDMP 327
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
P F E+ + ++ + R P CP + ++MK CW+ RP
Sbjct 328 YPDLSFSEV------------TSAVVRQNLRPEIPRCCPSSLANVMKRCWDANPEKRPEM 375
Query 1163 ENLIPILKTVHEKYQGQA 1180
E ++ +L+ + G
Sbjct 376 EEVVAMLEAIDTSKGGGM 393
Score = 205 bits (522), Expect = 1e-56, Method: Composition-based stats.
Identities = 66/339 (19%), Positives = 119/339 (35%), Gaps = 69/339 (20%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D ++ S + +GT V+ G + G+D V +
Sbjct 101 WEIDPSKLIIKSVIARGTFGTVHRG--------------------IYDGQD------VAV 134
Query 642 KVLDPSHH---------DIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN--------- 683
K+LD + AF + ++ ++ H ++ G + E
Sbjct 135 KLLDWGEEGHRSDAEIASLRAAFTQEVAVWHKLDHPNVTKFIGAAMGTSEMSIQTENGQM 194
Query 684 -------IMVTEYVEHGPLDVWL-RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNV 735
+V EY G L +L + R + + ++ LA LSYL ++ +VH +V
Sbjct 195 GMPSNVCCVVVEYCPGGALKSFLIKTRRRKLAFKVVIQLSLDLARGLSYLHSQKIVHRDV 254
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSL 791
N+LL + S +K++D GV + ++APE L G +
Sbjct 255 KTENMLLDK-------SRTLKIADFGVARLEASNPNDMTGETGTLGYMAPEVLNG--SPY 305
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH---RLPEPSCPQLATLTSQC 848
+ D + FG L EI + P S SE RQ+ +P LA + +C
Sbjct 306 NRKCDVYSFGICLWEIYCC-DMPYPDLSFSEVTSAVVRQNLRPEIPRCCPSSLANVMKRC 364
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
P +RP ++ L + ++ +
Sbjct 365 WDANPEKRPEMEEVVAMLEAIDTSKGGGMIPPDQQQGCF 403
>sp|Q62371|DDR2_MOUSE Discoidin domain-containing receptor 2 OS=Mus
musculus OX=10090 GN=Ddr2 PE=1 SV=2
Length=854
Score = 263 bits (673), Expect = 8e-73, Method: Composition-based stats.
Identities = 97/292 (33%), Positives = 144/292 (49%), Gaps = 35/292 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGE------------MVAVKALKADCGPQHRSGWKQEID 949
LGEG FG+V L + + +VAVK L+AD R+ + +EI
Sbjct 568 KLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIK 627
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----------SIGLAQ 999
I+ L +II+ C E L ++ EY+ G L +L RH ++ A
Sbjct 628 IMSRLKDPNIIRLLAVCI--TEDPLCMITEYMENGDLNQFLSRHEPLSSCSSDATVSYAN 685
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
L A QI GM YL + +++HRDLA RN L+ + +KI DFG+++ + G +YYR++
Sbjct 686 LKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSG-DYYRIQG 744
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
P+ W + E + KF ASDVW+FGVTL+E T C Q P L + +
Sbjct 745 RAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC---QEQPYSQLSDEQVIENTG 801
Query 1120 TVLRLTELLERGER--LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
R ++G + LP+P CP VY LM +CW E RP+F+ + +L
Sbjct 802 EFFR-----DQGRQIYLPQPALCPDSVYKLMLSCWRRETKHRPSFQEIHLLL 848
Score = 233 bits (593), Expect = 3e-62, Method: Composition-based stats.
Identities = 74/315 (23%), Positives = 123/315 (39%), Gaps = 42/315 (13%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L+ ++ +K + LG+G V+ + E + +
Sbjct 548 LSGKDVAVEEFPRKLLAFKEKLGEGQFGEVH--------LCEVEGMEKFKDKDFALDVSA 599
Query 634 GQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
Q + V +K+L + A F + +MS++ ++ + VC+ M+TEY+E+
Sbjct 600 NQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIRLLAVCITEDPLCMITEYMEN 659
Query 693 GPLDVWLRRERG--------HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
G L+ +L R V A +A Q+AS + YL + N VH ++ RN L+
Sbjct 660 GDLNQFLSRHEPLSSCSSDATVSYANLKFMATQIASGMKYLSSLNFVHRDLATRNCLV-- 717
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKW 798
G + IK++D G+ S + V I W++ E + G +TA D W
Sbjct 718 -----GKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLG--KFTTASDVW 770
Query 799 GFGATLLEIC-FDGEAPLQSRSPSEKEH-----FYQRQHRL----PEPSCPQLATLTSQC 848
FG TL E F E P S + F + ++ P + L C
Sbjct 771 AFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQIYLPQPALCPDSVYKLMLSC 830
Query 849 LTYEPTQRPSFRTIL 863
E RPSF+ I
Sbjct 831 WRRETKHRPSFQEIH 845
>sp|Q9SYM9|Y1853_ARATH Receptor-like serine/threonine-protein
kinase At1g78530 OS=Arabidopsis thaliana OX=3702 GN=At1g78530
PE=2 SV=1
Length=355
Score = 249 bits (637), Expect = 8e-73, Method: Composition-based stats.
Identities = 76/307 (25%), Positives = 129/307 (42%), Gaps = 17/307 (6%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933
+ + +S +SD + L LG G FG V D AVK L
Sbjct 52 MVMFRSQLLNSVSSDMFMKKTHKLSNKDILGSGGFGTVYRLVID-----DSTTFAVKRLN 106
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-R 992
+ R G+ +E++ + + H +I+ G L+ E +P GSL +L R
Sbjct 107 RGTSERDR-GFHRELEAMADIKHRNIVTLHGYFTSPHYN--LLIYELMPNGSLDSFLHGR 163
Query 993 HSIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
++ A A G++YLH H IHRD+ + N+LLD++ ++ DFGLA +
Sbjct 164 KALDWASRYRIAVGAARGISYLHHDCIPHIIHRDIKSSNILLDHNMEARVSDFGLATLME 223
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF- 1108
+ V + APE K DV+SFGV L ELLT + +
Sbjct 224 PDKTH--VSTFVAGTFGYLAPEYFDTGKATMKGDVYSFGVVLLELLTGRKPTDDEFFEEG 281
Query 1109 LELIGIAQGQMTVLRLTELLERGERLP--RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+L+ +G + R +++ R + ++ +V+ + C E E + RP ++
Sbjct 282 TKLVTWVKGVVRDQREEVVIDNRLRGSSVQENEEMNDVFGIAMMCLEPEPAIRPAMTEVV 341
Query 1167 PILKTVH 1173
+L+ +
Sbjct 342 KLLEYIK 348
Score = 207 bits (526), Expect = 7e-58, Method: Composition-based stats.
Identities = 64/338 (19%), Positives = 120/338 (36%), Gaps = 69/338 (20%)
Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620
+++ R + + ++ H++ K+I LG G VY RL ++ S
Sbjct 52 MVMFRSQLLNSVSSDMFMKKTHKLSNKDI-----LGSGGFGTVY--RLVIDDSTTF---- 100
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680
+K L+ + F+ M+ + H ++ +HG
Sbjct 101 -------------------AVKRLNRGTSERDRGFHRELEAMADIKHRNIVTLHGYFTSP 141
Query 681 PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCG 737
N+++ E + +G LD +L R + A + +A A +SYL + +++H ++
Sbjct 142 HYNLLIYELMPNGSLDSFLHG-RKALDWASRYRIAVGAARGISYLHHDCIPHIIHRDIKS 200
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLS 792
NILL + ++SD G+ + V +LAPE G ++
Sbjct 201 SNILLDH-------NMEARVSDFGLATLMEPDKTHVSTFVAGTFGYLAPEYFDTGKATM- 252
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR--------------QHRL----- 833
D + FG LLE+ G P E +RL
Sbjct 253 -KGDVYSFGVVLLELL-TGRKPTDDEFFEEGTKLVTWVKGVVRDQREEVVIDNRLRGSSV 310
Query 834 -PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ + CL EP RP+ +++ L ++
Sbjct 311 QENEEMNDVFGIAMMCLEPEPAIRPAMTEVVKLLEYIK 348
>sp|Q9CAH1|Y1725_ARATH Putative receptor-like protein kinase At1g72540
OS=Arabidopsis thaliana OX=3702 GN=At1g72540 PE=2 SV=1
Length=450
Score = 253 bits (645), Expect = 9e-73, Method: Composition-based stats.
Identities = 81/321 (25%), Positives = 135/321 (42%), Gaps = 15/321 (5%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---E 925
+ ++ ++ +N + + K LGEG FG+V D + TG +
Sbjct 56 ISLNDFSNSFFINIHIFTYEELKTITQGFSKYNFLGEGGFGEVYKGFVDDSLK-TGLKDQ 114
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
VAVKALK + G HR W E+ IL L H H++ G C + E+ LV EY+ G+
Sbjct 115 PVAVKALKREGGQGHRE-WLAEVIILGQLKHPHLVNLVGYCCEDDER--LLVYEYMERGN 171
Query 986 LRDYLPRH---SIGLAQLLLFAQQICEGMAYLH--AQHYIHRDLAARNVLLDNDRLVKIG 1040
L D+L + ++ + +G+ +LH + I+RD N+LL +D K+
Sbjct 172 LEDHLFQKYGGALPWLTRVKILLGAAKGLEFLHKQEKPVIYRDFKPSNILLSSDFSSKLS 231
Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT-HCD 1099
DFGLA E + + + APE + SDV+SFGV L E+LT
Sbjct 232 DFGLATDGSEEEDSNFTKS-VMGTEGYAAPEYISAGNLTTMSDVFSFGVVLLEMLTARKA 290
Query 1100 SSQSPPTKFLELIGIAQGQM-TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
+ + L+ A+ + +L +++ + + L C
Sbjct 291 VEKYRAQRGRNLVEWARPMLKDPNKLERIIDPSLEGKYSVEGIRKAAALAYQCLSHNPKS 350
Query 1159 RPTFENLIPILKTVHEKYQGQ 1179
RPT ++ L+ + + Q
Sbjct 351 RPTMTTVVKTLEPILDLKDIQ 371
Score = 230 bits (586), Expect = 8e-65, Method: Composition-based stats.
Identities = 70/343 (20%), Positives = 133/343 (39%), Gaps = 56/343 (16%)
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEGS 613
+ SN I ++ +N+ ++ + + ++ + LG+G VY+G +
Sbjct 49 SDFSNSTISLNDFSNSFFINIHIFTYEELKTITQGFSKYNFLGEGGFGEVYKGFVDDSLK 108
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
++ V +K L + ++ Q+ H HL +
Sbjct 109 TGL------------------KDQPVAVKALKREGGQGHREWLAEVIILGQLKHPHLVNL 150
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLE--NKNL 730
G C E ++V EY+E G L+ L ++ G +P ++ + A L +L K +
Sbjct 151 VGYCCEDDERLLVYEYMERGNLEDHLFQKYGGALPWLTRVKILLGAAKGLEFLHKQEKPV 210
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECL 784
++ + NILL+ + KLSD G+ E+ + + APE +
Sbjct 211 IYRDFKPSNILLSSDFSS-------KLSDFGLATDGSEEEDSNFTKSVMGTEGYAAPEYI 263
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ------HRLPEPSC 838
G +L+T D + FG LLE+ +A + R+ + + ++L
Sbjct 264 SAG--NLTTMSDVFSFGVVLLEMLTARKAVEKYRAQRGRNLVEWARPMLKDPNKLERIID 321
Query 839 PQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRL 869
P L A L QCL++ P RP+ T+++ L +
Sbjct 322 PSLEGKYSVEGIRKAAALAYQCLSHNPKSRPTMTTVVKTLEPI 364
>sp|P97504|BMX_MOUSE Cytoplasmic tyrosine-protein kinase BMX OS=Mus
musculus OX=10090 GN=Bmx PE=2 SV=1
Length=651
Score = 258 bits (660), Expect = 1e-72, Method: Composition-based stats.
Identities = 97/351 (28%), Positives = 155/351 (44%), Gaps = 29/351 (8%)
Query 829 RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA-- 886
+ + + + +L + C P + + H ++ P S A
Sbjct 323 KHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPVSVALG 382
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
S + + +++LG G FG V L + D VAVK +K G + Q
Sbjct 383 SGIWELKREEITLLKELGNGQFGVVQLGQWKGQYD-----VAVKMIKE--GAMSEDEFFQ 435
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFA 1004
E + L H ++K+ G C + + +V EY+ G L +YL H GL QLL
Sbjct 436 EAQTMMKLSHPKLVKFYGVCSKK--YPIYIVTEYITNGCLLNYLKSHGKGLESCQLLEMC 493
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+CEGMA+L + +IHRDLAARN L+D+D VK+ DFG+ + V + + Y P
Sbjct 494 YDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLD--DQYVSSVGTKFP 551
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
V W APE +K+ SDVW+FG+ ++E+ + L +
Sbjct 552 VKWSAPEVFHYFKYSSKSDVWAFGILMWEVFS--------------LGKQPYDLYDNSEV 597
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+ +G RL RP +Y +M +CW RPTF+ L+ ++ + E+
Sbjct 598 VVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPLREQ 648
Score = 255 bits (652), Expect = 1e-71, Method: Composition-based stats.
Identities = 83/436 (19%), Positives = 161/436 (37%), Gaps = 64/436 (15%)
Query 449 DGIHGPLLEPFVQAKLRPE--DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFP 506
D G + + LR + +G +++ S+ + TV+ S+A + + ++ +
Sbjct 271 DWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQMG---MYTVSLFSKAVNDKKGT-VKHYH 326
Query 507 IEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRG 566
+ + F S+ +L Q + LR +
Sbjct 327 VHTNAENKLYLAENYCFDSIPKLIHYHQHN---SAGMITRLRHP------------VSTK 371
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
A P ++ L + ++EIT L LG G V G+ +
Sbjct 372 ANKVPVSVALGS-GIWELKREEITLLKELGNGQFGVVQLGQWKG---------------- 414
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+ V +K++ F++ A M ++SH L +GVC + +V
Sbjct 415 ---------QYDVAVKMIKEGAMS-EDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIV 464
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
TEY+ +G L +L+ + + + + +++LE+ +H ++ RN L+
Sbjct 465 TEYITNGCLLNYLKSHGKGLESCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVD--- 521
Query 747 LAEGTSPFIKLSDPGVGLGALSREE--RVER---IPWLAPECLPGGANSLSTAMDKWGFG 801
+ +K+SD G+ L + V + W APE S+ D W FG
Sbjct 522 ----SDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFH--YFKYSSKSDVWAFG 575
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859
+ E+ G+ P SE + HRL P+ + + + C P +RP+F
Sbjct 576 ILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTF 635
Query 860 RTILRDLTRLQPHNLA 875
+ +L + L+ +
Sbjct 636 QQLLSAIEPLREQDKP 651
>sp|Q07E01|MET_ORNAN Hepatocyte growth factor receptor OS=Ornithorhynchus
anatinus OX=9258 GN=MET PE=3 SV=1
Length=1382
Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats.
Identities = 87/287 (30%), Positives = 136/287 (47%), Gaps = 19/287 (7%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
+ +G GHFG V ND AVK+L + S + E I++
Sbjct 1078 MVHFTEIIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFS 1136
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAY 1013
H +++ G C + L +V+ Y+ G LR+++ H+ + L+ F Q+ +GM Y
Sbjct 1137 HPNVLSLLGICLRREGSPL-VVLPYMKHGDLRNFIRNESHNPTVKDLIGFGLQVAKGMKY 1195
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPEC 1072
L ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E
Sbjct 1196 LASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALES 1255
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
L+ KF SDVWSFGV L+EL+T + +T L +G
Sbjct 1256 LQTQKFTSKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGR 1301
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
RL +P+ CP ++ +M CW A RP+F L+ + + + G+
Sbjct 1302 RLLQPEYCPDPLFEVMLKCWHPNAEMRPSFSELVSKIAVIFSTFIGE 1348
Score = 228 bits (581), Expect = 2e-59, Method: Composition-based stats.
Identities = 68/401 (17%), Positives = 135/401 (34%), Gaps = 42/401 (10%)
Query 507 IEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRG 566
+ + + FP+ + G+ Q A P + + +
Sbjct 997 VSNESVDYRATFPEDQFPNSSQNGSCRQAHYPLADLSPILSSGDSNPSSPLLQSNVHIDI 1056
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+ +P + Q D + +G+G VY G L
Sbjct 1057 SALNPDLVQAVQHVVIGPDSLMVHFTEIIGRGHFGCVYHGTLLDND-------------- 1102
Query 627 LVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENI 684
+++ +K L+ + + F +M SH ++ + G+C+R +
Sbjct 1103 -------DKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNVLSLLGICLRREGSPL 1155
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+V Y++HG L ++R E + + + Q+A + YL +K VH ++ RN +L
Sbjct 1156 VVLPYMKHGDLRNFIRNESHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDE 1215
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVE--------RIPWLAPECLPGGANSLSTAMD 796
+K++D G+ +E + W+A E L ++ D
Sbjct 1216 K-------FTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQT--QKFTSKSD 1266
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854
W FG L E+ G P + + + + RL PE L + +C
Sbjct 1267 VWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLFEVMLKCWHPNAE 1326
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895
RPSF ++ + + + + + + V
Sbjct 1327 MRPSFSELVSKIAVIFSTFIGEHYVHVNATYVNVKCVAPYP 1367
>sp|Q06806|TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mus
musculus OX=10090 GN=Tie1 PE=1 SV=3
Length=1134
Score = 267 bits (682), Expect = 1e-72, Method: Composition-based stats.
Identities = 105/351 (30%), Positives = 147/351 (42%), Gaps = 40/351 (11%)
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
CL T + + + L P V + +GE
Sbjct 784 RSCLHRRRTFTYQSGSGEETILQFSSGTLTLTRRPKPQPEPLSYPVLEWEDITFEDLIGE 843
Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKG 964
G+FG+V DG A+K LK + E+++L L +H +II G
Sbjct 844 GNFGQVIRAMIK--KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 901
Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFAQQI 1007
CE++G L + +EY P G+L D+L + ++ QLL FA
Sbjct 902 ACENRG--YLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDA 959
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
GM YL + +IHRDLAARNVL+ + KI DFGL++ G E Y + G PV W
Sbjct 960 ANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSR----GEEVYVKKTMGRLPVRW 1015
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
A E L + SDVWSFGV L+E+++ L G MT L E
Sbjct 1016 MAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCGMTCAELYEK 1061
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
L +G R+ +P C EVY LM+ CW RP F + L + E +
Sbjct 1062 LPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARKA 1112
Score = 239 bits (610), Expect = 2e-63, Method: Composition-based stats.
Identities = 69/352 (20%), Positives = 130/352 (37%), Gaps = 58/352 (16%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
+ L + R + P L+ L + ++IT +G+G V ++ +G
Sbjct 809 SGTLTLTRRPKPQPEPLSYPVLEW-----EDITFEDLIGEGNFGQVIRAMIKKDGL---- 859
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQV-SHTHLAFVHG 675
++ +K+L + + F ++ ++ H ++ + G
Sbjct 860 ------------------KMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 901
Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLAS 720
C + EY +G L +LR+ R + + A A+
Sbjct 902 ACENRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAAN 961
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP-- 777
+ YL K +H ++ RN+L+ G + K++D G+ G + ++ + R+P
Sbjct 962 GMQYLSEKQFIHRDLAARNVLV-------GENLASKIADFGLSRGEEVYVKKTMGRLPVR 1014
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PE 835
W+A E L + +T D W FG L EI G P + +E + +R+ P
Sbjct 1015 WMAIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPR 1072
Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
++ L QC P +RP F I L R+ A V ++
Sbjct 1073 NCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARKAYVNMSLFENFTY 1124
>sp|Q9XI87|VIK_ARATH Serine/threonine-protein kinase VIK OS=Arabidopsis
thaliana OX=3702 GN=VIK PE=1 SV=1
Length=438
Score = 252 bits (643), Expect = 1e-72, Method: Composition-based stats.
Identities = 75/281 (27%), Positives = 125/281 (44%), Gaps = 32/281 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960
+G+G FG++ + G VAVK + ++ E+D+L L H +I+
Sbjct 168 IGKGSFGEIVKAYWR------GTPVAVKRILPSLSDDRLVIQDFRHEVDLLVKLRHPNIV 221
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQH- 1018
++ G ++ K L L+ EY+ G L YL + + + FA I GM YLH +
Sbjct 222 QFLGAVTER--KPLMLITEYLRGGDLHQYLKEKGGLTPTTAVNFALDIARGMTYLHNEPN 279
Query 1019 -YIHRDLAARNVLL--DNDRLVKIGDFGLAKAVPEGHEYYRVREDG-DSPVFWYAPECLK 1074
IHRDL RNVLL + +K+GDFGL+K + + + + G + APE K
Sbjct 280 VIIHRDLKPRNVLLVNSSADHLKVGDFGLSKLIKVQNSHDVYKMTGETGSYRYMAPEVFK 339
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
++ DV+SF + LYE+L + + G R
Sbjct 340 HRRYDKKVDVFSFAMILYEMLEGEPPF---------------ANHEPYEAAKHVSDGHRP 384
Query 1135 P-RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
R C ++ L+ CW+ + + RP+F +++ L+ + E
Sbjct 385 TFRSKGCTPDLRELIVKCWDADMNQRPSFLDILKRLEKIKE 425
Score = 219 bits (558), Expect = 4e-61, Method: Composition-based stats.
Identities = 61/315 (19%), Positives = 115/315 (37%), Gaps = 53/315 (17%)
Query 582 HRVDQKEITQLS--HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
++ E+ + +G+G+ + + R V
Sbjct 153 WEIEPAELDFSNAAMIGKGSFGEIVKAYWRG--------------------------TPV 186
Query 640 VLKVLDPSHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+K + PS D + F L+ ++ H ++ G +++TEY+ G L
Sbjct 187 AVKRILPSLSDDRLVIQDFRHEVDLLVKLRHPNIVQFLGAVTERKPLMLITEYLRGGDLH 246
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPF 754
+L +E+G + + A +A ++YL N+ ++H ++ RN+LL ++
Sbjct 247 QYL-KEKGGLTPTTAVNFALDIARGMTYLHNEPNVIIHRDLKPRNVLL-----VNSSADH 300
Query 755 IKLSDPGVGL--------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+K+ D G+ ++APE +D + F L E
Sbjct 301 LKVGDFGLSKLIKVQNSHDVYKMTGETGSYRYMAPEVFKH--RRYDKKVDVFSFAMILYE 358
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP---SCPQLATLTSQCLTYEPTQRPSFRTIL 863
+ +GE P + P E HR P L L +C + QRPSF IL
Sbjct 359 ML-EGEPPFANHEPYEAAKHVSDGHRPTFRSKGCTPDLRELIVKCWDADMNQRPSFLDIL 417
Query 864 RDLTRLQPHNLADVL 878
+ L +++ +D
Sbjct 418 KRLEKIKETLPSDHH 432
>sp|Q9LQQ8|PBL5_ARATH Probable serine/threonine-protein kinase
PBL5 OS=Arabidopsis thaliana OX=3702 GN=PBL5 PE=2 SV=1
Length=423
Score = 251 bits (641), Expect = 2e-72, Method: Composition-based stats.
Identities = 81/301 (27%), Positives = 135/301 (45%), Gaps = 19/301 (6%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
+ LGEG FGKV + + ++VA+K L + G Q + E+ L
Sbjct 102 NFRSDCFLGEGGFGKVFKGTIEKLD----QVVAIKQLDRN-GVQGIREFVVEVLTLSLAD 156
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEG 1010
H +++K G C + ++ LV EY+P GSL D+L + + + A G
Sbjct 157 HPNLVKLIGFCAEGDQR--LLVYEYMPQGSLEDHLHVLPSGKKPLDWNTRMKIAAGAARG 214
Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH + I+RDL N+LL D K+ DFGLAK P G + + V +
Sbjct 215 LEYLHDRMTPPVIYRDLKCSNILLGEDYQPKLSDFGLAKVGPSGDKTH-VSTRVMGTYGY 273
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLR-LT 1125
AP+ + + SD++SFGV L EL+T + + T K L+G A+ R
Sbjct 274 CAPDYAMTGQLTFKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLFKDRRNFP 333
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV-HEKYQGQAPSVF 1184
++++ + P + + + C + + + RP +++ L + KY +PS
Sbjct 334 KMVDPLLQGQYPVRGLYQALAISAMCVQEQPTMRPVVSDVVLALNFLASSKYDPNSPSSS 393
Query 1185 S 1185
S
Sbjct 394 S 394
Score = 222 bits (566), Expect = 3e-62, Method: Composition-based stats.
Identities = 63/370 (17%), Positives = 119/370 (32%), Gaps = 66/370 (18%)
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
+ +T +L+ LG+G V++G +
Sbjct 82 QVTGKKAQTFTFQELA---EATGNFRSDCFLGEGGFGKVFKGTIEKLDQ----------- 127
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
V +K LD + F +S H +L + G C G + +
Sbjct 128 -------------VVAIKQLDRNGVQGIREFVVEVLTLSLADHPNLVKLIGFCAEGDQRL 174
Query 685 MVTEYVEHGPLDVWLR---RERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGR 738
+V EY+ G L+ L + + +M +A A L YL ++ +++ ++
Sbjct 175 LVYEYMPQGSLEDHLHVLPSGKKPLDWNTRMKIAAGAARGLEYLHDRMTPPVIYRDLKCS 234
Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLS 792
NILL G KLSD G+ S ++ + + AP+ G L+
Sbjct 235 NILL-------GEDYQPKLSDFGLAKVGPSGDKTHVSTRVMGTYGYCAPDYAMTG--QLT 285
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ------RQHRLPEPSCPQL----- 841
D + FG LLE+ +A +++ ++ + P+ P L
Sbjct 286 FKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLFKDRRNFPKMVDPLLQGQYP 345
Query 842 -------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894
+++ C+ +PT RP ++ L L +
Sbjct 346 VRGLYQALAISAMCVQEQPTMRPVVSDVVLALNFLASSKYDPNSPSSSSGKNPSFHRDRD 405
Query 895 RYLKKIRDLG 904
K+ +
Sbjct 406 DEEKRPHLVK 415
>sp|F4HQ17|LRL14_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE
PROTEIN KINASE-like 1.4 OS=Arabidopsis thaliana
OX=3702 GN=LRK10L-1.4 PE=2 SV=2
Length=663
Score = 258 bits (660), Expect = 2e-72, Method: Composition-based stats.
Identities = 78/319 (24%), Positives = 139/319 (44%), Gaps = 22/319 (7%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH 940
+ R+LG+G FG V G VAVK L + +
Sbjct 318 YCGVQVFSYEELEEATENFSRELGDGGFGTVYYGVLK-----DGRAVAVKRL-YERSLKR 371
Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SI 995
+K EI+IL++L H +++ G C + + L LV EY+ G+L ++L + +
Sbjct 372 VEQFKNEIEILKSLKHPNLVILYG-CTSRHSRELLLVYEYISNGTLAEHLHGNRAEARPL 430
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ L A + +++LH + IHRD+ N+LLD++ VK+ DFGL++ P +
Sbjct 431 CWSTRLNIAIETASALSFLHIKGIIHRDIKTTNILLDDNYQVKVADFGLSRLFPMDQTHI 490
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGI 1114
G + PE + Y+ SDV+SFGV L EL++ ++ + + L +
Sbjct 491 STAPQG--TPGYVDPEYYQCYQLNEKSDVYSFGVVLTELISSKEAVDITRHRHDINLANM 548
Query 1115 AQGQMTVLRLTELLERGERLPRPDKC---PCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
A ++ L EL++ + V L C + E RP + ++ IL+
Sbjct 549 AVSKIQNNALHELVDSSLGYDNDPEVRRKMMAVAELAFRCLQQERDVRPAMDEIVEILRG 608
Query 1172 VHEKYQG----QAPSVFSV 1186
+ + + ++P V +
Sbjct 609 IKDDEKKRVLVKSPDVVDI 627
Score = 210 bits (535), Expect = 4e-56, Method: Composition-based stats.
Identities = 59/326 (18%), Positives = 109/326 (33%), Gaps = 63/326 (19%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
+ S+ +++ LG G VY G L+
Sbjct 319 CGVQVFSYEELEEATENFSRELGDGGFGTVYYGVLKDGR--------------------- 357
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV-CVRGPENIMVTEYVEH 692
V +K L F ++ + H +L ++G E ++V EY+ +
Sbjct 358 ----AVAVKRLYERSLKRVEQFKNEIEILKSLKHPNLVILYGCTSRHSRELLLVYEYISN 413
Query 693 GPLDVWLRRERG---HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
G L L R + + ++ +A + ASALS+L K ++H ++ NILL
Sbjct 414 GTLAEHLHGNRAEARPLCWSTRLNIAIETASALSFLHIKGIIHRDIKTTNILLD------ 467
Query 750 GTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+ +K++D G+ + + ++ PE L+ D + FG L
Sbjct 468 -DNYQVKVADFGLSRLFPMDQTHISTAPQGTPGYVDPEYYQ--CYQLNEKSDVYSFGVVL 524
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLP--------------------EPSCPQLATL 844
E+ EA +R + ++ +A L
Sbjct 525 TELISSKEAVDITRHRHDINLANMAVSKIQNNALHELVDSSLGYDNDPEVRRKMMAVAEL 584
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQ 870
+CL E RP+ I+ L ++
Sbjct 585 AFRCLQQERDVRPAMDEIVEILRGIK 610
>sp|Q86AT8|SPKA_DICDI Stress-activated protein kinase alpha OS=Dictyostelium
discoideum OX=44689 GN=spkA-1 PE=1 SV=1
Length=638
Score = 257 bits (657), Expect = 2e-72, Method: Composition-based stats.
Identities = 81/334 (24%), Positives = 145/334 (43%), Gaps = 20/334 (6%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
T +P + P P +++ + + + L+ LG G G
Sbjct 305 TKKP-KTPELIIEEDPTPPDTPDISGLRHSLHTLRHVGEVNIINDNELEYTEKLGAGSSG 363
Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
KV Y G+ VA+K LK+ + +K+E I+ + +H++ + G
Sbjct 364 KVYKGLYR------GKEVAIKVLKSMTESKEIEEFKKEFQIMSAIRSKHVVHFYGAVL-- 415
Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSI--GLAQLLLFAQQICEGMAYLHA--QHYIHRDLA 1025
E L +VME GSL + +S+ G + FA + G+ LH +HRDL
Sbjct 416 -EPKLCMVMENCSRGSLYHVMDNNSLDIGWERTFRFAIETVRGIECLHKWDPPIVHRDLK 474
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
+ N+L+++ +K+ DFGL++ + V+ G + APE +F SDV+
Sbjct 475 SLNLLVNDKWEIKVCDFGLSRFNTGSNLETLVKMRG--TFAYCAPEVYYGEQFSGKSDVY 532
Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
S V L+EL+T C + + F E + Q + + ++ R P+ CP +
Sbjct 533 SIAVILWELVTRCINGRY-ERPFSEYKNL---QHDFQIIIQTAKKNLRPTIPNACPESLV 588
Query 1146 HLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L+++CW+ RPT +++ L T+ +Y+
Sbjct 589 SLIQDCWDPNLENRPTCTDILSRLVTIENEYRSN 622
Score = 182 bits (463), Expect = 6e-47, Method: Composition-based stats.
Identities = 58/346 (17%), Positives = 108/346 (31%), Gaps = 60/346 (17%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
P P +T ++ +R + + R + + ++ E+ LG G+ VY+G R +
Sbjct 319 PTPPDTPDISGLRHSLHTLRHVG----EVNIINDNELEYTEKLGAGSSGKVYKGLYRGK- 373
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLA 671
V +KVL + F + +MS + H+
Sbjct 374 -------------------------EVAIKVLKSMTESKEIEEFKKEFQIMSAIRSKHVV 408
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE--NKN 729
+G + P+ MV E G L + + A + + L +
Sbjct 409 HFYGAVLE-PKLCMVMENCSRGSLYHVMDNNSLDIGWERTFRFAIETVRGIECLHKWDPP 467
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-----ERVERIPWLAPECL 784
+VH ++ N+L+ IK+ D G+ + + APE
Sbjct 468 IVHRDLKSLNLLVNDK-------WEIKVCDFGLSRFNTGSNLETLVKMRGTFAYCAPEVY 520
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR------------QHR 832
G S D + L E+ R SE ++ +
Sbjct 521 YG--EQFSGKSDVYSIAVILWELVTRCINGRYERPFSEYKNLQHDFQIIIQTAKKNLRPT 578
Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+P L +L C RP+ IL L ++ +++
Sbjct 579 IPNACPESLVSLIQDCWDPNLENRPTCTDILSRLVTIENEYRSNIQ 624
>sp|Q9ZUF4|RIPK_ARATH Serine/threonine-protein kinase RIPK OS=Arabidopsis
thaliana OX=3702 GN=RIPK PE=1 SV=1
Length=462
Score = 252 bits (643), Expect = 2e-72, Method: Composition-based stats.
Identities = 83/283 (29%), Positives = 127/283 (45%), Gaps = 13/283 (5%)
Query 901 RDLGEGHFGKVSLYCYDPTND--GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
LGEG FG V D + VAVK L + HR W E+ L L H++
Sbjct 91 NFLGEGGFGPVHKGFIDDKLRPGLKAQPVAVKLLDLEGLQGHRE-WLTEVMFLGQLKHKN 149
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLH 1015
++K G C ++ ++ LV E++P GSL + L R S+ + + A G+ +LH
Sbjct 150 LVKLIGYCCEEEHRT--LVYEFMPRGSLENQLFRRYSASLPWSTRMKIAHGAATGLQFLH 207
Query 1016 A--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
I+RD A N+LLD+D K+ DFGLAK PEG + + V + APE +
Sbjct 208 EAENPVIYRDFKASNILLDSDYTAKLSDFGLAKDGPEGDDTH-VSTRVMGTQGYAAPEYI 266
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTELLERG 1131
SDV+SFGV L ELLT S + ++ L+ A+ + R L+ +++
Sbjct 267 MTGHLTARSDVYSFGVVLLELLTGRRSVDKKRSSREQNLVDWARPMLNDPRKLSRIMDPR 326
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ + L C RP ++ IL + +
Sbjct 327 LEGQYSETGARKAATLAYQCLSHRPKNRPCMSAVVSILNDLKD 369
Score = 234 bits (598), Expect = 3e-66, Method: Composition-based stats.
Identities = 73/346 (21%), Positives = 131/346 (38%), Gaps = 54/346 (16%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
L++ L+ +V + + + LG+G V++G + +D L PG
Sbjct 70 SDLHVFTLAELKVITQSFSSTNFLGEGGFGPVHKGFI---------------DDKLRPGL 114
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+ V +K+LD + + Q+ H +L + G C +V E++
Sbjct 115 ---KAQPVAVKLLDLEGLQGHREWLTEVMFLGQLKHKNLVKLIGYCCEEEHRTLVYEFMP 171
Query 692 HGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLA 748
G L+ L R +P + +M +A A+ L +L +++ + NILL
Sbjct 172 RGSLENQLFRRYSASLPWSTRMKIAHGAATGLQFLHEAENPVIYRDFKASNILLD----- 226
Query 749 EGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+ KLSD G+ ++ + + APE + G L+ D + FG
Sbjct 227 --SDYTAKLSDFGLAKDGPEGDDTHVSTRVMGTQGYAAPEYIMTG--HLTARSDVYSFGV 282
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQ------HRLPEPSCPQL------------ATL 844
LLE+ + + RS E+ + +L P+L ATL
Sbjct 283 VLLELLTGRRSVDKKRSSREQNLVDWARPMLNDPRKLSRIMDPRLEGQYSETGARKAATL 342
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
QCL++ P RP ++ L L+ +N + T P +
Sbjct 343 AYQCLSHRPKNRPCMSAVVSILNDLKDYNDIPMGTFTYTVPNTPDN 388
>sp|Q03351|NTRK3_RAT NT-3 growth factor receptor OS=Rattus norvegicus
OX=10116 GN=Ntrk3 PE=1 SV=2
Length=864
Score = 262 bits (670), Expect = 3e-72, Method: Composition-based stats.
Identities = 114/373 (31%), Positives = 162/373 (43%), Gaps = 73/373 (20%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914
P I + + N P + +R + R+LGEG FGKV L
Sbjct 497 GPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAE 556
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
CY+ + +VAVKALK D R +++E ++L L HEHI+K+ G C D L
Sbjct 557 CYNLSPTKDKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PL 613
Query 975 QLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQ 1017
+V EY+ G L +L H +GL+Q+L A QI GM YL +Q
Sbjct 614 IMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQ 673
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAV----------------------------- 1048
H++HRDLA RN L+ + LVKIGDFG+++ V
Sbjct 674 HFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYREGPYQKGPFSVSWQQQRLAASA 733
Query 1049 ------PEGHEYYRVREDGD---SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
P G+++ E G P+ W PE + KF SDVWSFGV L+E+ T+
Sbjct 734 ASTLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGK 793
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
Q++ + E + +G L RP CP EVY +M CW+ E R
Sbjct 794 Q--------------PWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQR 839
Query 1160 PTFENLIPILKTV 1172
+ + IL +
Sbjct 840 LNIKEIYKILHAL 852
Score = 249 bits (636), Expect = 9e-68, Method: Composition-based stats.
Identities = 73/348 (21%), Positives = 126/348 (36%), Gaps = 90/348 (26%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ +++I LG+G V+ + + L P +D+ + V +K
Sbjct 533 IKRRDIVLKRELGEGAFGKVF----------------LAECYNLSPTKDK---MLVAVKA 573
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702
L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR
Sbjct 574 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633
Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+G + ++ + +A Q+AS + YL +++ VH ++ RN L+
Sbjct 634 PDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV------ 687
Query 749 EGTSPFIKLSDPGVGLGALSREE------------------------------------- 771
G + +K+ D G+ S +
Sbjct 688 -GANLLVKIGDFGMSRDVYSTDYYREGPYQKGPFSVSWQQQRLAASAASTLFNPSGNDFC 746
Query 772 --------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ I W+ PE + +T D W FG L EI G+ P S +E
Sbjct 747 IWCEVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEV 804
Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ L P ++ + C EP QR + + I + L L
Sbjct 805 IECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 852
>sp|P23049|SEA_AVIET Tyrosine-protein kinase transforming protein
SEA OS=Avian erythroblastosis virus (strain S13) OX=11863
GN=V-SEA PE=3 SV=2
Length=370
Score = 248 bits (634), Expect = 3e-72, Method: Composition-based stats.
Identities = 95/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+ R +G GHFG V Y G AVK+L + + +E +++ +H
Sbjct 61 HRSRVIGRGHFGSVYHGTYMDPLLG-NLHCAVKSLHRITYLEEVEEFLREGILMKGFHHP 119
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLH 1015
++ G C + L +V+ Y+ G LR ++ S + +L+ F Q+ GM YL
Sbjct 120 QVLSLLGVCLPRHGLPL-VVLPYMRHGDLRHFVRAQERSPTVKELIGFGLQVALGMEYLA 178
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE--DGDSPVFWYAPECL 1073
+ ++HRDLAARN +LD VK+ DFGLA+ V G EYY +R+ PV W A E L
Sbjct 179 QKKFVHRDLAARNCMLDETLTVKVADFGLARDVF-GKEYYSIRQHRHAKLPVRWMALESL 237
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ KF SDVWSFGV ++ELLT S ++ + L RG R
Sbjct 238 QTQKFTTKSDVWSFGVLMWELLTRGAS--------------PYPEVDPYDMARYLLRGRR 283
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
LP+P CP +Y +M +CW RP+F L+ L+ V +G+
Sbjct 284 LPQPQPCPDTLYGVMLSCWAPTPEERPSFSGLVCELERVLASLEGE 329
Score = 213 bits (543), Expect = 7e-60, Method: Composition-based stats.
Identities = 65/315 (21%), Positives = 115/315 (37%), Gaps = 44/315 (14%)
Query 564 MRGARASPRTLNLSQLSFHRVDQKEIT--QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
R L ++ + ++ + + +G+G +VY G G+
Sbjct 33 TSCCLEDLRPELLEEVKDILIPEERLITHRSRVIGRGHFGSVYHGTYMDPLLGNLHC--- 89
Query 622 DDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCV-R 679
+K L ++ + F LM H + + GVC+ R
Sbjct 90 ------------------AVKSLHRITYLEEVEEFLREGILMKGFHHPQVLSLLGVCLPR 131
Query 680 GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRN 739
++V Y+ HG L ++R + + + Q+A + YL K VH ++ RN
Sbjct 132 HGLPLVVLPYMRHGDLRHFVRAQERSPTVKELIGFGLQVALGMEYLAQKKFVHRDLAARN 191
Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSL 791
+L + +K++D G+ +E R + W+A E L
Sbjct 192 CMLDE-------TLTVKVADFGLARDVFGKEYYSIRQHRHAKLPVRWMALESLQT--QKF 242
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCPQ-LATLTSQCL 849
+T D W FG + E+ G +P P + + R RLP+ CP L + C
Sbjct 243 TTKSDVWSFGVLMWELLTRGASPYPEVDPYDMARYLLRGRRLPQPQPCPDTLYGVMLSCW 302
Query 850 TYEPTQRPSFRTILR 864
P +RPSF ++
Sbjct 303 APTPEERPSFSGLVC 317
>sp|Q16832|DDR2_HUMAN Discoidin domain-containing receptor 2 OS=Homo
sapiens OX=9606 GN=DDR2 PE=1 SV=2
Length=855
Score = 262 bits (669), Expect = 3e-72, Method: Composition-based stats.
Identities = 94/293 (32%), Positives = 142/293 (48%), Gaps = 36/293 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGE------------MVAVKALKADCGPQHRSGWKQEID 949
LGEG FG+V L + + +VAVK L+AD R+ + +EI
Sbjct 568 KLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIK 627
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------SIGLA 998
I+ L +II C + L ++ EY+ G L +L RH ++
Sbjct 628 IMSRLKDPNIIHLLAVCI--TDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYT 685
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
L A QI GM YL + +++HRDLA RN L+ + +KI DFG+++ + G +YYR++
Sbjct 686 NLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSG-DYYRIQ 744
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
P+ W + E + KF ASDVW+FGVTL+E T C Q P L + +
Sbjct 745 GRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC---QEQPYSQLSDEQVIENT 801
Query 1119 MTVLRLTELLERGER--LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
R ++G + LP+P CP VY LM +CW + RP+F+ + +L
Sbjct 802 GEFFR-----DQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849
Score = 234 bits (597), Expect = 9e-63, Method: Composition-based stats.
Identities = 75/316 (24%), Positives = 124/316 (39%), Gaps = 43/316 (14%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L+ ++ +K +T LG+G V+ + E + +
Sbjct 548 LSGKDVAVEEFPRKLLTFKEKLGEGQFGEVH--------LCEVEGMEKFKDKDFALDVSA 599
Query 634 GQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
Q + V +K+L + A F + +MS++ ++ + VC+ M+TEY+E+
Sbjct 600 NQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMEN 659
Query 693 GPLDVWLRRERGH---------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
G L+ +L R V +A Q+AS + YL + N VH ++ RN L+
Sbjct 660 GDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLV- 718
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDK 797
G + IK++D G+ S + V I W++ E + G +TA D
Sbjct 719 ------GKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLG--KFTTASDV 770
Query 798 WGFGATLLEIC-FDGEAPLQSRSPSEKE----HFYQRQHR-----LPEPSCPQLATLTSQ 847
W FG TL E F E P S + F++ Q R P + L
Sbjct 771 WAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLS 830
Query 848 CLTYEPTQRPSFRTIL 863
C + RPSF+ I
Sbjct 831 CWRRDTKNRPSFQEIH 846
>sp|Q26614|FGFR_STRPU Fibroblast growth factor receptor OS=Strongylocentrotus
purpuratus OX=7668 GN=FGFR PE=2 SV=1
Length=972
Score = 264 bits (674), Expect = 4e-72, Method: Composition-based stats.
Identities = 102/337 (30%), Positives = 153/337 (45%), Gaps = 35/337 (10%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
T S ++I + + D P F + L + +GEG FGKV +
Sbjct 596 TSVDSTQSIAPLFGGRNRLTSSLTVISEYDIPLDPEWEFPRDRLTVGKTIGEGAFGKVVI 655
Query 914 YCYDP-TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGE 971
VAVK LKA+ + S E+ +++ + + +II GCC +G
Sbjct 656 GEAVGIVCQEKTSTVAVKMLKANAMDREFSDLISELAMMKMIGKNPNIINLLGCCTQEGP 715
Query 972 KSLQLVMEYVPLGSLRDYLPRHSIGLA----------------QLLLFAQQICEGMAYLH 1015
+++E+ G+LRD+L L+ A Q+ GM +L
Sbjct 716 P--YVIVEFAHHGNLRDFLRSRRPPEEYEKSILLTTSQTLTNKDLMSMAYQVARGMDFLA 773
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
++ IHRDLAARNVL+ D +KI DFGLA+ + ++YR DG PV W APE L +
Sbjct 774 SKKCIHRDLAARNVLVTEDFEMKICDFGLARDIHY-IDFYRKTTDGRLPVKWMAPEALFD 832
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
F SDVWSFG+ L+E++T L G + V ++ + L G+RL
Sbjct 833 RMFTTQSDVWSFGILLWEIMT--------------LGGTPYPSVPVEQMFDYLRSGKRLE 878
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+P E+YH++ CW T RPTF L+ L +
Sbjct 879 KPQNTSLEIYHILCECWRTSPGQRPTFCELVEDLDRI 915
Score = 222 bits (566), Expect = 2e-58, Method: Composition-based stats.
Identities = 66/347 (19%), Positives = 121/347 (35%), Gaps = 52/347 (15%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ +T +G+G V + E G + K V +
Sbjct 632 WEFPRDRLTVGKTIGEGAFGKV----VIGEAVGIVCQEKTS---------------TVAV 672
Query 642 KVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
K+L + D ++M + + ++ + G C + ++ E+ HG L +L
Sbjct 673 KMLKANAMDREFSDLISELAMMKMIGKNPNIINLLGCCTQEGPPYVIVEFAHHGNLRDFL 732
Query 700 RRERGH--------------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
R R + M +A Q+A + +L +K +H ++ RN+L+
Sbjct 733 RSRRPPEEYEKSILLTTSQTLTNKDLMSMAYQVARGMDFLASKKCIHRDLAARNVLVTE- 791
Query 746 GLAEGTSPFIKLSDPGVGLGAL----SREERVERIP--WLAPECLPGGANSLSTAMDKWG 799
+K+ D G+ R+ R+P W+APE L +T D W
Sbjct 792 ------DFEMKICDFGLARDIHYIDFYRKTTDGRLPVKWMAPEALFDRM--FTTQSDVWS 843
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857
FG L EI G P S + + + RL P+ + ++ + +C P QRP
Sbjct 844 FGILLWEIMTLGGTPYPSVPVEQMFDYLRSGKRLEKPQNTSLEIYHILCECWRTSPGQRP 903
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
+F ++ DL R+ + + F +
Sbjct 904 TFCELVEDLDRIISVSSNQDYLDLEAVGDAPVKTFQESERMAFMGFR 950
>sp|Q00944|FAK1_CHICK Focal adhesion kinase 1 OS=Gallus gallus
OX=9031 GN=PTK2 PE=1 SV=2
Length=1053
Score = 265 bits (677), Expect = 4e-72, Method: Composition-based stats.
Identities = 98/294 (33%), Positives = 141/294 (48%), Gaps = 24/294 (8%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQH 940
P++ + ++ R +GEG FG V Y P N VA+K K
Sbjct 407 YTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPA--MAVAIKTCKNCTSDSV 464
Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLA 998
R + QE +R H HI+K G E + ++ME LG LR +L + S+ LA
Sbjct 465 REKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKFSLDLA 521
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
L+L+A Q+ +AYL ++ ++HRD+AARNVL+ VK+GDFGL++ + + Y
Sbjct 522 SLILYAYQLSTALAYLESKRFVHRDIAARNVLVSATDCVKLGDFGLSRYMEDS--TYYKA 579
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
G P+ W APE + +F ASDVW FGV ++E+L H
Sbjct 580 SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ--------------G 625
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ + +E GERLP P CP +Y LM CW + S RP F L L T+
Sbjct 626 VKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679
Score = 239 bits (609), Expect = 2e-63, Method: Composition-based stats.
Identities = 68/305 (22%), Positives = 123/305 (40%), Gaps = 39/305 (13%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
T + + + ++ I +G+G +V++G +
Sbjct 406 TYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQG---------------------IYMSP 444
Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+ V +K D F + A M Q H H+ + GV P ++ E
Sbjct 445 ENPAMAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCT 503
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G L +L+ + + +A ++ A QL++AL+YLE+K VH ++ RN+L++
Sbjct 504 LGELRSFLQVRKFSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS-------A 556
Query 752 SPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+ +KL D G+ I W+APE + ++A D W FG + E
Sbjct 557 TDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWE 614
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
I G P Q ++ + R +P P L +L ++C Y+P++RP F +
Sbjct 615 ILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKA 674
Query 865 DLTRL 869
L+ +
Sbjct 675 QLSTI 679
>sp|O81906|B120_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase B120 OS=Arabidopsis thaliana OX=3702 GN=B120
PE=2 SV=1
Length=849
Score = 261 bits (668), Expect = 4e-72, Method: Composition-based stats.
Identities = 83/284 (29%), Positives = 127/284 (45%), Gaps = 16/284 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
K +LG G FG V + G +AVK L G Q +K EI ++ L
Sbjct 527 NDFCKENELGRGGFGPVYKGVLE-----DGREIAVKRLSGKSG-QGVDEFKNEIILIAKL 580
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEG 1010
H ++++ GCC + EK LV EY+P SL +L + I + I G
Sbjct 581 QHRNLVRLLGCCFEGEEK--MLVYEYMPNKSLDFFLFDETKQALIDWKLRFSIIEGIARG 638
Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH IHRDL NVLLD + KI DFG+A+ G++ +
Sbjct 639 LLYLHRDSRLRIIHRDLKVSNVLLDAEMNPKISDFGMARIFG-GNQNEANTVRVVGTYGY 697
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
+PE E F SDV+SFGV L E+++ ++ ++ LIG A T R EL
Sbjct 698 MSPEYAMEGLFSVKSDVYSFGVLLLEIVSGKRNTSLRSSEHGSLIGYAWYLYTHGRSEEL 757
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
++ R+ + H+ C + A+ RP +++ +L++
Sbjct 758 VDPKIRVTCSKREALRCIHVAMLCVQDSAAERPNMASVLLMLES 801
Score = 232 bits (592), Expect = 3e-62, Method: Composition-based stats.
Identities = 54/262 (21%), Positives = 95/262 (36%), Gaps = 45/262 (17%)
Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
I++ G + L + L+ + + + + LG+G VY+G L
Sbjct 502 IMIEGKAVNTSELPVFSLNAIAIATNDFCKENELGRGGFGPVYKGVLEDGR--------- 552
Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
+ +K L F L++++ H +L + G C G
Sbjct 553 ----------------EIAVKRLSGKSGQGVDEFKNEIILIAKLQHRNLVRLLGCCFEGE 596
Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENK---NLVHGNVC 736
E ++V EY+ + LD +L E + WK+ + + +A L YL ++H ++
Sbjct 597 EKMLVYEYMPNKSLDFFLFDETKQALIDWKLRFSIIEGIARGLLYLHRDSRLRIIHRDLK 656
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANS 790
N+LL K+SD G+ + V +++PE G
Sbjct 657 VSNVLLD-------AEMNPKISDFGMARIFGGNQNEANTVRVVGTYGYMSPEYAMEGL-- 707
Query 791 LSTAMDKWGFGATLLEICFDGE 812
S D + FG LLEI
Sbjct 708 FSVKSDVYSFGVLLLEIVSGKR 729
>sp|Q8H1E3|PBL17_ARATH Probable serine/threonine-protein kinase
PBL17 OS=Arabidopsis thaliana OX=3702 GN=PBL17 PE=1 SV=1
Length=442
Score = 250 bits (639), Expect = 5e-72, Method: Composition-based stats.
Identities = 81/315 (26%), Positives = 134/315 (43%), Gaps = 13/315 (4%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG--TGEMVAVKA 931
++ N D + + + LGEG FG V D + VA+K
Sbjct 67 QSNPGYENVDIFTYEEMKIATKQFRPDYILGEGGFGVVYKGVIDESVRVGFKSTKVAIKE 126
Query 932 LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP 991
L + G Q W E++ L L H +++K G C + + LV EY+ +GSL +L
Sbjct 127 LNPE-GFQGDREWLAEVNYLGQLSHPNLVKLIGYCCEDDHR--LLVYEYMAMGSLEKHLF 183
Query 992 RH---SIGLAQLLLFAQQICEGMAYLH--AQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
R ++ + + A +G+A+LH + I+RDL N+LLD K+ DFGLAK
Sbjct 184 RRVGCTLTWTKRMKIALDAAKGLAFLHGAERSIIYRDLKTANILLDEGYNAKLSDFGLAK 243
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPP 1105
P G + + V + APE + SDV+ FGV L E+L + +S
Sbjct 244 DGPRGDQTH-VSTRVMGTYGYAAPEYVMTGHLTSRSDVYGFGVLLLEMLLGKRAMDKSRA 302
Query 1106 TKFLELIGIAQGQMT-VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ L+ A+ + +L +++ K +V L C RP +
Sbjct 303 CREHNLVEWARPLLNHNKKLLRIIDPRMDGQYGTKALMKVAGLAYQCLSQNPKGRPLMNH 362
Query 1165 LIPILKTVHEKYQGQ 1179
++ +L+T+ + Q
Sbjct 363 VVEVLETLKDDGDAQ 377
Score = 237 bits (605), Expect = 2e-67, Method: Composition-based stats.
Identities = 70/350 (20%), Positives = 129/350 (37%), Gaps = 56/350 (16%)
Query 564 MRGARASPRTLNLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
++ +++P N+ ++ + K+ LG+G VY+G +
Sbjct 63 IKDLQSNPGYENVDIFTYEEMKIATKQFRPDYILGEGGFGVVYKGVI------------- 109
Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
R + +V +K L+P + + + Q+SH +L + G C
Sbjct 110 -----DESVRVGFKSTKVAIKELNPEGFQGDREWLAEVNYLGQLSHPNLVKLIGYCCEDD 164
Query 682 ENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGR 738
++V EY+ G L+ L R G + +M +A A L++L +++++ ++
Sbjct 165 HRLLVYEYMAMGSLEKHLFRRVGCTLTWTKRMKIALDAAKGLAFLHGAERSIIYRDLKTA 224
Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLS 792
NILL KLSD G+ ++ + + APE + G L+
Sbjct 225 NILLDE-------GYNAKLSDFGLAKDGPRGDQTHVSTRVMGTYGYAAPEYVMTG--HLT 275
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--------------- 837
+ D +GFG LLE+ A +SR+ E + L
Sbjct 276 SRSDVYGFGVLLLEMLLGKRAMDKSRACREHNLVEWARPLLNHNKKLLRIIDPRMDGQYG 335
Query 838 ---CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884
++A L QCL+ P RP ++ L L+ A +
Sbjct 336 TKALMKVAGLAYQCLSQNPKGRPLMNHVVEVLETLKDDGDAQEEVMTNLH 385
>sp|P35590|TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 OS=Homo
sapiens OX=9606 GN=TIE1 PE=1 SV=1
Length=1138
Score = 265 bits (678), Expect = 5e-72, Method: Composition-based stats.
Identities = 103/351 (29%), Positives = 146/351 (42%), Gaps = 40/351 (11%)
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
CL T + + + L V + +GE
Sbjct 788 RSCLHRRRTFTYQSGSGEETILQFSSGTLTLTRRPKLQPEPLSYPVLEWEDITFEDLIGE 847
Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKG 964
G+FG+V DG A+K LK + E+++L L +H +II G
Sbjct 848 GNFGQVIRAMIK--KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 905
Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFAQQI 1007
C+++G L + +EY P G+L D+L + ++ QLL FA
Sbjct 906 ACKNRG--YLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDA 963
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
GM YL + +IHRDLAARNVL+ + KI DFGL++ G E Y + G PV W
Sbjct 964 ANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSR----GEEVYVKKTMGRLPVRW 1019
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
A E L + SDVWSFGV L+E+++ L G MT L E
Sbjct 1020 MAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCGMTCAELYEK 1065
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
L +G R+ +P C EVY LM+ CW RP F + L + E +
Sbjct 1066 LPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARKA 1116
Score = 238 bits (607), Expect = 5e-63, Method: Composition-based stats.
Identities = 69/352 (20%), Positives = 130/352 (37%), Gaps = 58/352 (16%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
+ L + R + P L+ L + ++IT +G+G V ++ +G
Sbjct 813 SGTLTLTRRPKLQPEPLSYPVLEW-----EDITFEDLIGEGNFGQVIRAMIKKDGL---- 863
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQV-SHTHLAFVHG 675
++ +K+L + + F ++ ++ H ++ + G
Sbjct 864 ------------------KMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 905
Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLAS 720
C + EY +G L +LR+ R + + A A+
Sbjct 906 ACKNRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAAN 965
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP-- 777
+ YL K +H ++ RN+L+ G + K++D G+ G + ++ + R+P
Sbjct 966 GMQYLSEKQFIHRDLAARNVLV-------GENLASKIADFGLSRGEEVYVKKTMGRLPVR 1018
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PE 835
W+A E L + +T D W FG L EI G P + +E + +R+ P
Sbjct 1019 WMAIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPR 1076
Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
++ L QC P +RP F I L R+ A V ++
Sbjct 1077 NCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARKAYVNMSLFENFTY 1128
>sp|Q95YD4|KIN32_CAEEL Inactive tyrosine-protein kinase kin-32
OS=Caenorhabditis elegans OX=6239 GN=kin-32 PE=1 SV=1
Length=867
Score = 261 bits (668), Expect = 5e-72, Method: Composition-based stats.
Identities = 94/282 (33%), Positives = 140/282 (50%), Gaps = 22/282 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V Y VAVK K D P QE ++R H +II+
Sbjct 373 IGGGQFGNVYKAVYHDLEKDERIAVAVKVCKTDAEPADTQLILQESSLMRNFRHSNIIQL 432
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C DQ + LV+E P G LR+YL + + L L LF QIC+ + YLH+ ++
Sbjct 433 IGVCVDQ---PMWLVLELAPKGELREYLQQEKDWLPLRILTLFCSQICDSLVYLHSTRFV 489
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+AARN+L+ + + VK+ DFGL++A+ Y R G P+ W APE + +F
Sbjct 490 HRDIAARNILVCSPQCVKLADFGLSRALDYDAVYTASR--GKLPIKWLAPESVNYRQFSM 547
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
ASDVW FGV ++E+ + L +T + +E+G R P P+KC
Sbjct 548 ASDVWMFGVCMWEIFS--------------LGVKPWAGVTNSDVIMHIEQGSRPPCPEKC 593
Query 1141 PCEVYHLMK-NCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
P +Y+ ++ W E RPT + + I++ V ++ P
Sbjct 594 PTALYNFIRSKMWAIEPHKRPTVDQIYAIIEDVRQQIIQNIP 635
Score = 214 bits (544), Expect = 4e-56, Method: Composition-based stats.
Identities = 80/367 (22%), Positives = 136/367 (37%), Gaps = 47/367 (13%)
Query 524 PSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHR 583
S+ L Q + F L+ E + M A P+T N + S R
Sbjct 310 QSLAHLLDGYQMLYNQRDSV-FKLKGI------ERCETLTMHEATIRPKTPN-NIDSNIR 361
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ ++ IT +G G NVY+ + ++ + + V +KV
Sbjct 362 LRRELITLKELIGGGQFGNVYKA--------------------VYHDLEKDERIAVAVKV 401
Query 644 LDPSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+ +SLM H+++ + GVCV P +V E G L +L++E
Sbjct 402 CKTDAEPADTQLILQESSLMRNFRHSNIIQLIGVCVDQP-MWLVLELAPKGELREYLQQE 460
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ +P+ + Q+ +L YL + VH ++ RNIL+ + +KL+D G+
Sbjct 461 KDWLPLRILTLFCSQICDSLVYLHSTRFVHRDIAARNILV-------CSPQCVKLADFGL 513
Query 763 GLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
I WLAPE + S A D W FG + EI G P
Sbjct 514 SRALDYDAVYTASRGKLPIKWLAPESV--NYRQFSMASDVWMFGVCMWEIFSLGVKPWAG 571
Query 818 RSPSEKEHFYQRQHRLPEP--SCPQLATLT-SQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
+ S+ ++ R P P L S+ EP +RP+ I + ++ +
Sbjct 572 VTNSDVIMHIEQGSRPPCPEKCPTALYNFIRSKMWAIEPHKRPTVDQIYAIIEDVRQQII 631
Query 875 ADVLTVN 881
++
Sbjct 632 QNIPPEQ 638
>sp|O65479|CRK20_ARATH Putative cysteine-rich receptor-like protein
kinase 20 OS=Arabidopsis thaliana OX=3702 GN=CRK20 PE=2
SV=2
Length=666
Score = 257 bits (656), Expect = 7e-72, Method: Composition-based stats.
Identities = 78/282 (28%), Positives = 122/282 (43%), Gaps = 18/282 (6%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
I LG+G FG+V + +G VAVK L + G Q ++ E+ ++ L H +
Sbjct 346 PINKLGQGGFGEVYKGTF-----PSGVQVAVKRLSKNSG-QGEKEFENEVVVVAKLQHRN 399
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYL 1014
++K G C + EK LV E+VP SL +L + + ++ I G+ YL
Sbjct 400 LVKLLGYCLEGEEK--ILVYEFVPNKSLDYFLFDPTMQGQLDWSRRYKIIGGIARGILYL 457
Query 1015 HAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
H IHRDL A N+LLD D K+ DFG+A+ R + APE
Sbjct 458 HQDSRLTIIHRDLKAGNILLDADMNPKVADFGMARIFGMDQTEANTRR-VVGTYGYMAPE 516
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLTELLE 1129
KF SDV+SFGV + E+++ +S L+ + +EL++
Sbjct 517 YAMYGKFSMKSDVYSFGVLVLEIVSGMKNSSLDQMDGSISNLVTYTWRLWSNGSPSELVD 576
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
H+ C + +A+ RPT ++ +L T
Sbjct 577 PSFGDNYQTSEITRCIHIALLCVQEDANDRPTMSAIVQMLTT 618
Score = 233 bits (593), Expect = 1e-63, Method: Composition-based stats.
Identities = 58/324 (18%), Positives = 108/324 (33%), Gaps = 65/324 (20%)
Query 573 TLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
T Q F + ++ LGQG VY+G
Sbjct 326 TAGSLQFDFKAIVAATDIFLPINKLGQGGFGEVYKGT----------------------- 362
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
++V +K L + F +++++ H +L + G C+ G E I+V E+V
Sbjct 363 --FPSGVQVAVKRLSKNSGQGEKEFENEVVVVAKLQHRNLVKLLGYCLEGEEKILVYEFV 420
Query 691 EHGPLDVWLRRE--RGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745
+ LD +L +G + + + + +A + YL + ++H ++ NILL
Sbjct 421 PNKSLDYFLFDPTMQGQLDWSRRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNILLD-- 478
Query 746 GLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
K++D G+ + V ++APE G S D +
Sbjct 479 -----ADMNPKVADFGMARIFGMDQTEANTRRVVGTYGYMAPEYAMYG--KFSMKSDVYS 531
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------------QL 841
FG +LEI + + + RL P +
Sbjct 532 FGVLVLEIVSGMKNSSLDQMDGSISNLVTYTWRLWSNGSPSELVDPSFGDNYQTSEITRC 591
Query 842 ATLTSQCLTYEPTQRPSFRTILRD 865
+ C+ + RP+ I++
Sbjct 592 IHIALLCVQEDANDRPTMSAIVQM 615
>sp|Q06805|TIE1_BOVIN Tyrosine-protein kinase receptor Tie-1 OS=Bos
taurus OX=9913 GN=TIE1 PE=2 SV=1
Length=1136
Score = 265 bits (677), Expect = 7e-72, Method: Composition-based stats.
Identities = 104/351 (30%), Positives = 147/351 (42%), Gaps = 40/351 (11%)
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
CL T + + + L P + V + +GE
Sbjct 786 KSCLHRRRTFTYQSGSGEETILQFSSGTLTLTRRPKPQPEPLNYPVLEWEDITFEDLIGE 845
Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKG 964
G+FG+V DG A+K LK + E+++L L +H +II G
Sbjct 846 GNFGQVIRAMIK--KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 903
Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFAQQI 1007
CE++G L + +EY P G+L D+L + ++ QLL FA
Sbjct 904 ACENRG--YLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDA 961
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
GM YL + +IHRDLAARNVL+ + KI DFGL++ G E Y + G PV W
Sbjct 962 ANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSR----GEEVYVKKTMGRLPVRW 1017
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
A E L + SDVWSFGV L+E+++ L G MT L E
Sbjct 1018 MAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCGMTCAELYEK 1063
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
L + R+ +P C EVY LM+ CW RP F + L + E +
Sbjct 1064 LPQAYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARKA 1114
Score = 239 bits (610), Expect = 2e-63, Method: Composition-based stats.
Identities = 70/352 (20%), Positives = 130/352 (37%), Gaps = 58/352 (16%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
+ L + R + P LN L + ++IT +G+G V ++ +G
Sbjct 811 SGTLTLTRRPKPQPEPLNYPVLEW-----EDITFEDLIGEGNFGQVIRAMIKKDGL---- 861
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQV-SHTHLAFVHG 675
++ +K+L + + F ++ ++ H ++ + G
Sbjct 862 ------------------KMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 903
Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLAS 720
C + EY +G L +LR+ R + + A A+
Sbjct 904 ACENRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAAN 963
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP-- 777
+ YL K +H ++ RN+L+ G + K++D G+ G + ++ + R+P
Sbjct 964 GMQYLSEKQFIHRDLAARNVLV-------GENLASKIADFGLSRGEEVYVKKTMGRLPVR 1016
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PE 835
W+A E L + +T D W FG L EI G P + +E + +R+ P
Sbjct 1017 WMAIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQAYRMEQPR 1074
Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
++ L QC P +RP F I L R+ A V ++
Sbjct 1075 NCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARKAYVNMSLFENFTY 1126
>sp|Q9SYA0|Y1150_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61500 OS=Arabidopsis thaliana OX=3702
GN=At1g61500 PE=2 SV=2
Length=804
Score = 260 bits (664), Expect = 7e-72, Method: Composition-based stats.
Identities = 85/350 (24%), Positives = 134/350 (38%), Gaps = 17/350 (5%)
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
L T R I ++L D
Sbjct 435 LTLFMILGFTAFGVWRCRVEHIAHISKDAWKNDLKPQDVPGLDFFDMHTIQNATNNFSLS 494
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG+G FG V G+ +AVK L + G Q + + EI ++ L H +++
Sbjct 495 NKLGQGGFGSVYKGKLQ-----DGKEIAVKRLSSSSG-QGKEEFMNEIVLISKLQHRNLV 548
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016
+ GCC ++ EK L+ E++ SL +L R I + Q I G+ YLH
Sbjct 549 RVLGCCIEEEEK--LLIYEFMVNKSLDTFLFDSRKRLEIDWPKRFDIIQGIARGLLYLHH 606
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRDL N+LLD KI DFGLA+ + +G EY + + +PE
Sbjct 607 DSRLRVIHRDLKVSNILLDEKMNPKISDFGLAR-MYQGTEYQDNTRRVVGTLGYMSPEYA 665
Query 1074 KEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
F SD++SFGV + E+++ S S + LI A + R +LL++
Sbjct 666 WTGMFSEKSDIYSFGVLMLEIISGEKISRFSYGVEGKTLIAYAWESWSEYRGIDLLDQDL 725
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182
+ C + + + RP L+ +L T + + P+
Sbjct 726 ADSCHPLEVGRCIQIGLLCVQHQPADRPNTLELLAMLTTTSDLPSPKQPT 775
Score = 235 bits (599), Expect = 2e-63, Method: Composition-based stats.
Identities = 53/247 (21%), Positives = 95/247 (38%), Gaps = 45/247 (18%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L+ + + + + LGQG +VY+G+L+
Sbjct 476 LDFFDMHTIQNATNNFSLSNKLGQGGFGSVYKGKLQDGK--------------------- 514
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ +K L S F L+S++ H +L V G C+ E +++ E++ +
Sbjct 515 ----EIAVKRLSSSSGQGKEEFMNEIVLISKLQHRNLVRVLGCCIEEEEKLLIYEFMVNK 570
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748
LD +L R + + W + + Q +A L YL + ++H ++ NILL
Sbjct 571 SLDTFLFDSRKRLEIDWPKRFDIIQGIARGLLYLHHDSRLRVIHRDLKVSNILLDEK--- 627
Query 749 EGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGA 802
K+SD G+ E + V + +++PE G S D + FG
Sbjct 628 ----MNPKISDFGLARMYQGTEYQDNTRRVVGTLGYMSPEYAWTGM--FSEKSDIYSFGV 681
Query 803 TLLEICF 809
+LEI
Sbjct 682 LMLEIIS 688
>sp|P42687|SPK1_GIRTI Tyrosine-protein kinase SPK-1 OS=Girardia
tigrina OX=6162 PE=2 SV=1
Length=497
Score = 252 bits (643), Expect = 7e-72, Method: Composition-based stats.
Identities = 81/474 (17%), Positives = 166/474 (35%), Gaps = 86/474 (18%)
Query 431 SHYLCHEVAPPRLVM---SIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTV 487
S+Y+ + P+ V I+ K+ + G Y+I S L+V
Sbjct 86 SNYVSKQDGSPQSVEAWREIQRW-----EAEKSLMKIGLQKGTYIIRPSRKE-NSYALSV 139
Query 488 AQRSQAPDGMQSLRLRKFPIE--QQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCF 545
+ + ++ F I+ Q + R+FP++ L + + G+
Sbjct 140 RDFDEK---KKICIVKHFQIKTLQDEKGISYSVNIRNFPNILTLIQFYEKNGI--GNTHI 194
Query 546 SLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605
L ++ + ++++ I L+ +G+G +V+
Sbjct 195 PLTDPMPDNYQ---------------PPVHFQDI---EINRENIEILNEIGRGFFGSVHR 236
Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV 665
+ G+ V K+L S + F A +M ++
Sbjct 237 AKW-------------------------GRSYEVAAKMLQSSKAE-REKFVLEAKIMHKL 270
Query 666 SHTHLAFVHGVCVRGP--ENIMVTEYVEHGPLDVWLRRERGHVP-MAWKMVVAQQLASAL 722
H + + GVC +++ EY+++G L +L+ G + + + +++ +
Sbjct 271 RHRKIVELLGVCTEPQDMPMLIIVEYMKNGSLKEYLKTPDGKKTNLNQMVHMMAEISEGM 330
Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGALSREERVERI 776
+YLE++ +VH ++ NIL+A K++D G+ LG ++
Sbjct 331 AYLESEKVVHRDLRADNILVANDLTR-------KVADFGLTELTDGSLGDQEKKTLRFPY 383
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836
W APE ++ D W +G + EI +P E + +R+P P
Sbjct 384 KWTAPEAAKSKV--FTSKSDVWSYGIVMFEILTWASSPYPDIPAKEVIEKVSKGYRMPNP 441
Query 837 -------SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
CP + + C P +RP+F + + L L + +
Sbjct 442 EKFITGVCCPDEIYKIMIWCWDANPEKRPTFLVLQEKMDLLIVDTLTNNAYYSH 495
Score = 250 bits (638), Expect = 3e-71, Method: Composition-based stats.
Identities = 82/302 (27%), Positives = 132/302 (44%), Gaps = 31/302 (10%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+ ++ ++ + ++G G FG V + G VA
Sbjct 193 HIPLTDPMPDNYQPPVHFQDIEINRENIEILNEIGRGFFGSVHRAKW-----GRSYEVAA 247
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K L R + E I+ L H I++ G C + + + +++EY+ GSL++Y
Sbjct 248 KML--QSSKAEREKFVLEAKIMHKLRHRKIVELLGVCTEPQDMPMLIIVEYMKNGSLKEY 305
Query 990 LP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
L L Q++ +I EGMAYL ++ +HRDL A N+L+ ND K+ DFGL
Sbjct 306 LKTPDGKKTNLNQMVHMMAEISEGMAYLESEKVVHRDLRADNILVANDLTRKVADFGL-T 364
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
+ +G + ++ P W APE K F SDVWS+G+ ++E+LT
Sbjct 365 ELTDGSLGDQEKKTLRFPYKWTAPEAAKSKVFTSKSDVWSYGIVMFEILT---------- 414
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDK------CPCEVYHLMKNCWETEASFRP 1160
+ + E + +G R+P P+K CP E+Y +M CW+ RP
Sbjct 415 ----WASSPYPDIPAKEVIEKVSKGYRMPNPEKFITGVCCPDEIYKIMIWCWDANPEKRP 470
Query 1161 TF 1162
TF
Sbjct 471 TF 472
>sp|P97523|MET_RAT Hepatocyte growth factor receptor OS=Rattus
norvegicus OX=10116 GN=Met PE=1 SV=1
Length=1382
Score = 266 bits (681), Expect = 8e-72, Method: Composition-based stats.
Identities = 88/285 (31%), Positives = 138/285 (48%), Gaps = 19/285 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G GHFG V + DG AVK+L + S + E I++ H
Sbjct 1080 HFNEVIGRGHFGCVYHGTLLDS-DGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHP 1138
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015
+++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL
Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLV 1197
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074
++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+
Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
KF SDVWSFGV L+EL+T + +T L +G RL
Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITIYLLQGRRL 1303
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+P+ CP +Y +M CW +A RP+ L+ + ++ + G+
Sbjct 1304 LQPEYCPDALYEVMLKCWHPKAEMRPSVSELVSRISSIFSTFIGE 1348
Score = 228 bits (581), Expect = 1e-59, Method: Composition-based stats.
Identities = 63/328 (19%), Positives = 120/328 (37%), Gaps = 42/328 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHH 649
+G+G VY G L G+++ +K L+ +
Sbjct 1081 FNEVIGRGHFGCVYHGTLLDSD---------------------GKKIHCAVKSLNRITDI 1119
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ F +M SH ++ + G+C+R ++V Y++HG L ++R E + +
Sbjct 1120 EEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A + YL +K VH ++ RN +L +K++D G+
Sbjct 1180 KDLIGFGLQVAKGMKYLVSKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232
Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+E + W+A E L +T D W FG L E+ G P +
Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290
Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + RL PE L + +C + RPS ++ ++ + + +
Sbjct 1291 FDITIYLLQGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSVSELVSRISSIFSTFIGEHY 1350
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + V L +D +G
Sbjct 1351 VHVNATYVNVKCVAPYPSLLPSQDNIDG 1378
>sp|Q91738|FAK1_XENLA Focal adhesion kinase 1 OS=Xenopus laevis
OX=8355 GN=ptk2 PE=2 SV=2
Length=1068
Score = 264 bits (674), Expect = 8e-72, Method: Composition-based stats.
Identities = 95/315 (30%), Positives = 146/315 (46%), Gaps = 24/315 (8%)
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPT 919
+ + + + + + + ++ R +GEG FG V Y P
Sbjct 399 ETDDYAEIIDEEDTYTMPSKSYGLDEAGDYEIQRDRIELGRCIGEGQFGDVHQGVYMSPE 458
Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979
N VA+K K R + QE +R H HI+K G E + ++ME
Sbjct 459 NPA--MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIME 513
Query 980 YVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037
LG LR +L ++S+ LA L+L++ Q+ +AYL ++ ++HRD+AARNVL+ + V
Sbjct 514 LCTLGELRSFLQVRKYSLDLASLILYSYQLSTALAYLESKRFVHRDIAARNVLVSSSDCV 573
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
K+GDFGL++ + + Y G P+ W APE + +F ASDVW FGV ++E+L +
Sbjct 574 KLGDFGLSRYMEDS--TYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMY 631
Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157
+ + +E GERLP P CP +Y LM CW + S
Sbjct 632 GVKPFQ--------------GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPS 677
Query 1158 FRPTFENLIPILKTV 1172
RP F L L T+
Sbjct 678 RRPRFTELKAQLSTI 692
Score = 237 bits (604), Expect = 8e-63, Method: Composition-based stats.
Identities = 69/308 (22%), Positives = 125/308 (41%), Gaps = 39/308 (13%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
++ L + + + + I +G+G +V++G V
Sbjct 416 PSKSYGLDEAGDYEIQRDRIELGRCIGEGQFGDVHQG---------------------VY 454
Query 630 GRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+ V +K D F + A M Q H H+ + GV P ++ E
Sbjct 455 MSPENPAMAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIME 513
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
G L +L+ + + +A ++ + QL++AL+YLE+K VH ++ RN+L++
Sbjct 514 LCTLGELRSFLQVRKYSLDLASLILYSYQLSTALAYLESKRFVHRDIAARNVLVS----- 568
Query 749 EGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGAT 803
+S +KL D G+ I W+APE + ++A D W FG
Sbjct 569 --SSDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVC 624
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRT 861
+ EI G P Q ++ + R +P P L +L ++C Y+P++RP F
Sbjct 625 MWEILMYGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTE 684
Query 862 ILRDLTRL 869
+ L+ +
Sbjct 685 LKAQLSTI 692
Score = 38.5 bits (88), Expect = 0.50, Method: Composition-based stats.
Identities = 33/198 (17%), Positives = 71/198 (36%), Gaps = 39/198 (20%)
Query 120 PAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHF 179
P ++ Q + D + + ++Q K+++++++A +
Sbjct 117 PEEWKYELRIRYLPKGFVNQFTE--DKPTLNFFYQQVKNDYMSEIADQVD---------- 164
Query 180 KNESLGMAFLHLCHL-------ALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRL 232
+ +L + L + AL E + K K P+S ++ + R
Sbjct 165 QEIALKLGCLEIRRSYGEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTL--RK 222
Query 233 RLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAP--RFGTERVP-------VCHLRLL 283
++ FR+F L+++ ++K+ E L+P R+ E + + L
Sbjct 223 LIQQTFRQF------ANLNREESILKF---FEILSPVYRYDKECFKCALGSSWIISVELA 273
Query 284 AQAEGEPCYIRDSGVAPT 301
E Y+ D G PT
Sbjct 274 IGPEEGISYLTDKGSNPT 291
>sp|F1N9Y5|KSYK_CHICK Tyrosine-protein kinase SYK OS=Gallus gallus
OX=9031 GN=SYK PE=1 SV=2
Length=613
Score = 255 bits (651), Expect = 8e-72, Method: Composition-based stats.
Identities = 96/272 (35%), Positives = 138/272 (51%), Gaps = 21/272 (8%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHII 960
+LG G+FG V Y + VAVK LK + P + +E ++++ L + +I+
Sbjct 354 ELGSGNFGTVKKGFYKMKKGA--KPVAVKILKNESNDPAIKDELLREANVMQQLDNPYIV 411
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G CE ++ LVME LG L +L ++ + + Q+ GM YL ++
Sbjct 412 RMIGICE---AEAWMLVMEMAELGPLNKFLQKNRHVTEKNITELVHQVSMGMKYLEENNF 468
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDLAARNVLL KI DFGL+KA+ YY+ + G PV WYAPEC+ YKF
Sbjct 469 VHRDLAARNVLLVTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECMNFYKFS 528
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SDVWSFGV ++E ++ M + +++ERGER+ P+
Sbjct 529 SKSDVWSFGVLMWEAFSYGQK--------------PYKGMKGGEVAQMIERGERMECPEA 574
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
CP EVY LMK CW RP F + L+
Sbjct 575 CPVEVYDLMKLCWTYNVDDRPGFVAVELRLRN 606
Score = 228 bits (580), Expect = 3e-62, Method: Composition-based stats.
Identities = 102/563 (18%), Positives = 183/563 (33%), Gaps = 135/563 (24%)
Query 380 FRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVA 439
F D+ +++E+ LE ++ S+ L +L A ++H E
Sbjct 119 FEDLKENLIREYVKQTWNLQGHALEQAIISQKPQLE---------KLIATTAH----EKM 165
Query 440 PPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAPDG 496
P HG + + ++ +G +LI S+ L + DG
Sbjct 166 P---------WFHGRISREESEHRILIGSRNNGKFLIRERDSN-GSYALCL-----LNDG 210
Query 497 MQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPG 556
+ + I++ + G+ F ++ +L + L C
Sbjct 211 K----VLHYRIDRDKTGKLSIPDGKRFDTLWQLVEHYS---YKPDGLLRVLSIPCPRHGS 263
Query 557 ETSNLI------------------------------IMRGAR---------------ASP 571
E+ N++ +++ AR
Sbjct 264 ESDNVVFDTRPLPGTPSKLQTPIGAPSDDQTPFNPYVLQRARGLIGAEKGDQREALPMDT 323
Query 572 RTLNLSQLSFHRVDQKEITQLSH--------LGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
+ K +T LG G V +G +++ P
Sbjct 324 EVYESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGAKP------- 376
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
V +K+L +D I A++M Q+ + ++ + G+C
Sbjct 377 ---------------VAVKILKNESNDPAIKDELLREANVMQQLDNPYIVRMIGIC-EAE 420
Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
++V E E GPL+ +L++ R HV + Q++ + YLE N VH ++ RN+L
Sbjct 421 AWMLVMEMAELGPLNKFLQKNR-HVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVL 479
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTA 794
L T + K+SD G+ + E + + W APEC+ S+
Sbjct 480 L-------VTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECM--NFYKFSSK 530
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYE 852
D W FG + E G+ P + E +R R+ PE ++ L C TY
Sbjct 531 SDVWSFGVLMWEAFSYGQKPYKGMKGGEVAQMIERGERMECPEACPVEVYDLMKLCWTYN 590
Query 853 PTQRPSFRTILRDLTRLQPHNLA 875
RP F + L
Sbjct 591 VDDRPGFVAVELRLRNYYYDISH 613
Score = 36.6 bits (83), Expect = 1.8, Method: Composition-based stats.
Identities = 22/107 (21%), Positives = 36/107 (34%), Gaps = 15/107 (14%)
Query 453 GPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQ 509
G + + L DGLYL+ S ++ L++A ++ + IE+
Sbjct 17 GNITREEAEEYLMQGGMSDGLYLLRQSRNYLGGFALSLAY---------GRKVHHYTIER 67
Query 510 QDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPG 556
+ G+S S EL A LR+ PG
Sbjct 68 ELSGTYAIAGGKSHASPAELINYHSEE---ADGLICLLRKSFNRPPG 111
>sp|Q3U1V8|M3K9_MOUSE Mitogen-activated protein kinase kinase
kinase 9 OS=Mus musculus OX=10090 GN=Map3k9 PE=2 SV=2
Length=1077
Score = 264 bits (675), Expect = 9e-72, Method: Composition-based stats.
Identities = 92/293 (31%), Positives = 135/293 (46%), Gaps = 41/293 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP---QHRSGWKQEIDILRTLYHEHI 959
+G G FGKV + G+ VAVKA + D Q +QE + L H +I
Sbjct 143 IGIGGFGKVYRAFWA------GDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPNI 196
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
I +G C E +L LVME+ G L L I L+ +A QI GM YLH +
Sbjct 197 IALRGVCLK--EPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIARGMNYLHDEAI 254
Query 1018 -HYIHRDLAARNVLL-------D-NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
IHRDL + N+L+ D +++++KI DFGLA+ + + W
Sbjct 255 VPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLAR-----EWHRTTKMSAAGTYAWM 309
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
APE ++ F SDVWS+GV L+ELLT P + ++ + +A G +
Sbjct 310 APEVIRASMFSKGSDVWSYGVLLWELLTG-----EVPFRGIDGLAVAYG---------VA 355
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
LP P CP LM++CW + RP+F +++ L T+ E + P
Sbjct 356 MNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTSILDQLTTIEESGFFEMP 408
Score = 237 bits (605), Expect = 5e-63, Method: Composition-based stats.
Identities = 90/483 (19%), Positives = 169/483 (35%), Gaps = 75/483 (16%)
Query 513 AFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPR 572
+ G + ++ L +GD+ + + SN + R A +S
Sbjct 55 EYEAAGEDELTLRLGDVVEVLSKDSQVSGDEGWWTGQLNQRVGIFPSNYVTPRSAFSSRC 114
Query 573 TLN------LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+ +D E+T +G G VY +
Sbjct 115 QPGAEDPSCYPPIQLLEIDFAELTLEEIIGIGGFGKVYRAFWAGD--------------- 159
Query 627 LVPGRDRGQELRVVLKVL----DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
V +K D + A L + + H ++ + GVC++ P
Sbjct 160 -----------EVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPN 208
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRN 739
+V E+ GPL+ L +R +P + A Q+A ++YL ++ ++H ++ N
Sbjct 209 LCLVMEFARGGPLNRVLSGKR--IPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSN 266
Query 740 IL-LARLGLAEGTSPFIKLSDPGVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMD 796
IL L ++ + ++ +K++D G+ ++ W+APE + A+ S D
Sbjct 267 ILILQKVENGDLSNKILKITDFGLAREWHRTTKMSAAGTYAWMAPEVIR--ASMFSKGSD 324
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEP 853
W +G L E+ GE P + + + +P A L C +P
Sbjct 325 VWSYGVLLWELL-TGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDP 383
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
RPSF +IL LT ++ ++ + D + ++R
Sbjct 384 HSRPSFTSILDQLTTIEESGFFEMPKDSFHCLQDDWKHEIQEMFDQLRA----------- 432
Query 914 YCYDPTNDGTGEM----VAV--KALKADCGPQHRSGWKQEIDIL-RTLYHEHIIKYKGCC 966
T E A+ K + + + ++EIDIL R L +II C
Sbjct 433 ---KEKELRTWEEELTRAALQQKNQEELLRRREQELAEREIDILEREL---NII-IHQLC 485
Query 967 EDQ 969
+++
Sbjct 486 QEK 488
>sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase
kinase 11 OS=Homo sapiens OX=9606 GN=MAP3K11 PE=1 SV=1
Length=847
Score = 260 bits (665), Expect = 9e-72, Method: Composition-based stats.
Identities = 92/293 (31%), Positives = 128/293 (44%), Gaps = 41/293 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR---SGWKQEIDILRTLYHEHI 959
+G G FGKV + GE+VAVKA + D +QE + L H +I
Sbjct 123 IGIGGFGKVYRGSWR------GELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNI 176
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
I K C + E +L LVMEY G L L + L+ +A QI GM YLH +
Sbjct 177 IALKAVCLE--EPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLHCEAL 234
Query 1018 -HYIHRDLAARNVLL--------DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
IHRDL + N+LL + +KI DFGLA+ + + W
Sbjct 235 VPVIHRDLKSNNILLLQPIESDDMEHKTLKITDFGLAR-----EWHKTTQMSAAGTYAWM 289
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
APE +K F SDVWSFGV L+ELLT P + ++ + +A G
Sbjct 290 APEVIKASTFSKGSDVWSFGVLLWELLTG-----EVPYRGIDCLAVAYGVAVN------- 337
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
LP P CP LM +CW + RP F +++ L+ + + + P
Sbjct 338 --KLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLREMP 388
Score = 219 bits (559), Expect = 5e-58, Method: Composition-based stats.
Identities = 71/314 (23%), Positives = 120/314 (38%), Gaps = 36/314 (11%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+E+ +G G VY G R E + DED V
Sbjct 113 SFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISV---------------- 156
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
A + + A L + ++H ++ + VC+ P +V EY GPL L R
Sbjct 157 ------TAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRR- 209
Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSP-FIKLSDP 760
VP + A Q+A + YL + ++H ++ NILL + ++ +K++D
Sbjct 210 -VPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIESDDMEHKTLKITDF 268
Query 761 GVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
G+ ++ W+APE + A++ S D W FG L E+ GE P +
Sbjct 269 GLAREWHKTTQMSAAGTYAWMAPEVIK--ASTFSKGSDVWSFGVLLWELL-TGEVPYRGI 325
Query 819 SPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ + +P A L + C +P +RP F +IL+ L L+ L
Sbjct 326 DCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLR 385
Query 876 DVLTVNPDSPASDP 889
++ + S
Sbjct 386 EMPRDSFHSMQEGW 399
>sp|Q8MY86|FGFR1_DUGJA Fibroblast growth factor receptor 1 OS=Dugesia
japonica OX=6161 GN=FGFR1 PE=2 SV=1
Length=854
Score = 260 bits (665), Expect = 9e-72, Method: Composition-based stats.
Identities = 91/327 (28%), Positives = 158/327 (48%), Gaps = 33/327 (10%)
Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPTNDGTGE 925
L+ + + ++ + ++ + LGEG FG V D N
Sbjct 521 YGLRKSSSFEFFSLYEFPCDAKWEFPREKLKITNKKLGEGAFGMVYEGIANDIGNRSNPI 580
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
VAVK ++ D + + +E++I++ + H ++I+ G C +G L++++E P G
Sbjct 581 KVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQKG--PLRVIVELAPYG 638
Query 985 SLRDYLPR------------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032
+LRD++ + + L ++ QI GM YL ++ +HRDL+ARN+L+
Sbjct 639 NLRDFVRAKNKKYSKSKKIIGNFTSSILCTYSLQIARGMTYLASRSVVHRDLSARNILVG 698
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
+KI DFGL + V YYR + DG PV W APE L E K+ SDVWS+G+ L+
Sbjct 699 EHFEMKIADFGLTRIVDY---YYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLW 755
Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152
E+ T DS + ++ +L+ +G + P+P+ E+Y LM++CW
Sbjct 756 EIFTLGDS--------------PYSAILPEKVVDLIRKGFQNPKPELANFEIYRLMQHCW 801
Query 1153 ETEASFRPTFENLIPILKTVHEKYQGQ 1179
+ RP F ++ IL + ++ +
Sbjct 802 SLSSENRPNFFEIVEILIDIIQRIDDE 828
Score = 219 bits (559), Expect = 5e-58, Method: Composition-based stats.
Identities = 70/369 (19%), Positives = 133/369 (36%), Gaps = 52/369 (14%)
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEI------TQLSHLGQGTRTNVYEGRLR 609
++L + G R S S F + E LG+G VYEG
Sbjct 512 SGNNSLSLKYGLRKSSSFEFFSLYEFPCDAKWEFPREKLKITNKKLGEGAFGMVYEGIAN 571
Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQV-SH 667
G +R ++V +K++ D F + +M + H
Sbjct 572 DIG-------------------NRSNPIKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRH 612
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER----------GHVPMAWKMVVAQQ 717
++ + G+C + ++ E +G L ++R + G+ + + Q
Sbjct 613 PNVIQLLGLCTQKGPLRVIVELAPYGNLRDFVRAKNKKYSKSKKIIGNFTSSILCTYSLQ 672
Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--GALSREERVE- 774
+A ++YL ++++VH ++ RNIL+ G +K++D G+ R++
Sbjct 673 IARGMTYLASRSVVHRDLSARNILV-------GEHFEMKIADFGLTRIVDYYYRKKTDGI 725
Query 775 -RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833
+ W+APE L +T D W +G L EI G++P + P + ++ +
Sbjct 726 LPVKWMAPEALLE--KKYTTKSDVWSYGILLWEIFTLGDSPYSAILPEKVVDLIRKGFQN 783
Query 834 PEPSCPQL--ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV 891
P+P L C + RP+F I+ L + + S + +
Sbjct 784 PKPELANFEIYRLMQHCWSLSSENRPNFFEIVEILIDIIQRIDDEPEENIYHSELNYLKM 843
Query 892 FHKRYLKKI 900
K
Sbjct 844 ESDYLEPKC 852
>sp|Q61527|ERBB4_MOUSE Receptor tyrosine-protein kinase erbB-4
OS=Mus musculus OX=10090 GN=Erbb4 PE=1 SV=5
Length=1308
Score = 266 bits (679), Expect = 9e-72, Method: Composition-based stats.
Identities = 99/272 (36%), Positives = 140/272 (51%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + VA+K L GP+ + E I+ ++ H H+++
Sbjct 724 LGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRL 783
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C +QLV + +P G L DY+ H IG LL + QI +GM YL + +
Sbjct 784 LGVCLSPT---IQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV 840
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ + VKI DFGLA+ + EG E + G P+ W A EC+ KF +
Sbjct 841 HRDLAARNVLVKSPNHVKITDFGLARLL-EGDEKEYNADGGKMPIKWMALECIHYRKFTH 899
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T G + + +LLE+GERLP+P C
Sbjct 900 QSDVWSYGVTIWELMTFG--------------GKPYDGIPTREIPDLLEKGERLPQPPIC 945
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW +A RP F+ L +
Sbjct 946 TIDVYMVMVKCWMIDADSRPKFKELAAEFSRM 977
Score = 242 bits (617), Expect = 6e-64, Method: Composition-based stats.
Identities = 67/338 (20%), Positives = 131/338 (39%), Gaps = 39/338 (12%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P +Q + + E+ ++ LG G VY+G EG
Sbjct 699 TPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETV-------------- 744
Query 630 GRDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ V +K+L+ + + F + A +M+ + H HL + GVC+ P +VT+
Sbjct 745 ------KIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCL-SPTIQLVTQ 797
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ HG L ++ + ++ + Q+A + YLE + LVH ++ RN+L+
Sbjct 798 LMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPN-- 855
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+K++D G+ + + I W+A EC+ + D W +G
Sbjct 856 -----HVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIH--YRKFTHQSDVWSYGV 908
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860
T+ E+ G P E ++ RLP+P + + +C + RP F+
Sbjct 909 TIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFK 968
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898
+ + +R+ ++ D K +
Sbjct 969 ELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQN 1006
>sp|Q05609|CTR1_ARATH Serine/threonine-protein kinase CTR1 OS=Arabidopsis
thaliana OX=3702 GN=CTR1 PE=1 SV=1
Length=821
Score = 260 bits (664), Expect = 1e-71, Method: Composition-based stats.
Identities = 77/333 (23%), Positives = 142/333 (43%), Gaps = 37/333 (11%)
Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR---DLGEGHFG 909
P Q + + + ++ + + + +G G FG
Sbjct 504 PPQNMMRASNQIEAAPMNAPPISQPVPNRANRELGLDGDDMDIPWCDLNIKEKIGAGSFG 563
Query 910 KVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968
V + ++ VAVK L + D + + + +E+ I++ L H +I+ + G
Sbjct 564 TVHRAEWHGSD------VAVKILMEQDFHAERVNEFLREVAIMKRLRHPNIVLFMGAVTQ 617
Query 969 QGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQH--YIHR 1022
+L +V EY+ GSL L R + + L A + +GM YLH ++ +HR
Sbjct 618 P--PNLSIVTEYLSRGSLYRLLHKSGAREQLDERRRLSMAYDVAKGMNYLHNRNPPIVHR 675
Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082
DL + N+L+D VK+ DFGL++ + + + +P W APE L++ S
Sbjct 676 DLKSPNLLVDKKYTVKVCDFGLSRL--KASTFLSSKSAAGTPE-WMAPEVLRDEPSNEKS 732
Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE-RGERLPRPDKCP 1141
DV+SFGV L+EL T + G + ++ + + +RL P
Sbjct 733 DVYSFGVILWELAT---------------LQQPWGNLNPAQVVAAVGFKCKRLEIPRNLN 777
Query 1142 CEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+V +++ CW E RP+F ++ +L+ + +
Sbjct 778 PQVAAIIEGCWTNEPWKRPSFATIMDLLRPLIK 810
Score = 244 bits (623), Expect = 2e-66, Method: Composition-based stats.
Identities = 63/297 (21%), Positives = 119/297 (40%), Gaps = 45/297 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ ++ +G G+ V+ G ++ V + +
Sbjct 546 IPWCDLNIKEKIGAGSFGTVHRAEW------------------------HGSDVAVKILM 581
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702
H + F ++M ++ H ++ G + P +VTEY+ G L L +
Sbjct 582 EQDFHAERVNEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKSG 641
Query 703 -RGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R + ++ +A +A ++YL N+N +VH ++ N+L+ + +K+ D
Sbjct 642 AREQLDERRRLSMAYDVAKGMNYLHNRNPPIVHRDLKSPNLLVDKK-------YTVKVCD 694
Query 760 PGVGLGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ LS + W+APE L + + D + FG L E+ + P
Sbjct 695 FGLSRLKASTFLSSKSAAGTPEWMAPEVLRDEPS--NEKSDVYSFGVILWELATL-QQPW 751
Query 816 QSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ +P++ F ++ +P PQ+A + C T EP +RPSF TI+ L L
Sbjct 752 GNLNPAQVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNEPWKRPSFATIMDLLRPL 808
>sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kinase
11 OS=Rattus norvegicus OX=10116 GN=Map3k11 PE=1 SV=1
Length=850
Score = 260 bits (665), Expect = 1e-71, Method: Composition-based stats.
Identities = 92/293 (31%), Positives = 128/293 (44%), Gaps = 41/293 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR---SGWKQEIDILRTLYHEHI 959
+G G FGKV + GE+VAVKA + D +QE + L H +I
Sbjct 124 IGIGGFGKVYRGSWR------GELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNI 177
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
I K C + E +L LVMEY G L L + L+ +A QI GM YLH +
Sbjct 178 IALKAVCLE--EPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLHCEAL 235
Query 1018 -HYIHRDLAARNVLL--------DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
IHRDL + N+LL + +KI DFGLA+ + + W
Sbjct 236 VPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAR-----EWHKTTQMSAAGTYAWM 290
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
APE +K F SDVWSFGV L+ELLT P + ++ + +A G
Sbjct 291 APEVIKASTFSKGSDVWSFGVLLWELLTG-----EVPYRGIDCLAVAYGVAVN------- 338
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
LP P CP LM +CW + RP F +++ L+ + + + P
Sbjct 339 --KLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLREMP 389
Score = 219 bits (558), Expect = 6e-58, Method: Composition-based stats.
Identities = 71/314 (23%), Positives = 119/314 (38%), Gaps = 36/314 (11%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+E+ +G G VY G R E + DED V
Sbjct 114 SFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISV---------------- 157
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
A + + A L + ++H ++ + VC+ P +V EY GPL L R
Sbjct 158 ------TAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRR- 210
Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSP-FIKLSDP 760
VP + A Q+A + YL + ++H ++ NILL + + +K++D
Sbjct 211 -VPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDF 269
Query 761 GVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
G+ ++ W+APE + A++ S D W FG L E+ GE P +
Sbjct 270 GLAREWHKTTQMSAAGTYAWMAPEVIK--ASTFSKGSDVWSFGVLLWELL-TGEVPYRGI 326
Query 819 SPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ + +P A L + C +P +RP F +IL+ L L+ L
Sbjct 327 DCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLR 386
Query 876 DVLTVNPDSPASDP 889
++ + S
Sbjct 387 EMPRDSFHSMQEGW 400
>sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase
kinase 11 OS=Mus musculus OX=10090 GN=Map3k11 PE=1 SV=1
Length=850
Score = 260 bits (665), Expect = 1e-71, Method: Composition-based stats.
Identities = 92/293 (31%), Positives = 128/293 (44%), Gaps = 41/293 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR---SGWKQEIDILRTLYHEHI 959
+G G FGKV + GE+VAVKA + D +QE + L H +I
Sbjct 124 IGIGGFGKVYRGSWR------GELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNI 177
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
I K C + E +L LVMEY G L L + L+ +A QI GM YLH +
Sbjct 178 IALKAVCLE--EPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLHCEAL 235
Query 1018 -HYIHRDLAARNVLL--------DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
IHRDL + N+LL + +KI DFGLA+ + + W
Sbjct 236 VPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAR-----EWHKTTQMSAAGTYAWM 290
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
APE +K F SDVWSFGV L+ELLT P + ++ + +A G
Sbjct 291 APEVIKASTFSKGSDVWSFGVLLWELLTG-----EVPYRGIDCLAVAYGVAVN------- 338
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
LP P CP LM +CW + RP F +++ L+ + + + P
Sbjct 339 --KLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLREMP 389
Score = 219 bits (558), Expect = 6e-58, Method: Composition-based stats.
Identities = 71/314 (23%), Positives = 119/314 (38%), Gaps = 36/314 (11%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+E+ +G G VY G R E + DED V
Sbjct 114 SFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISV---------------- 157
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
A + + A L + ++H ++ + VC+ P +V EY GPL L R
Sbjct 158 ------TAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRR- 210
Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSP-FIKLSDP 760
VP + A Q+A + YL + ++H ++ NILL + + +K++D
Sbjct 211 -VPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDF 269
Query 761 GVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
G+ ++ W+APE + A++ S D W FG L E+ GE P +
Sbjct 270 GLAREWHKTTQMSAAGTYAWMAPEVIK--ASTFSKGSDVWSFGVLLWELL-TGEVPYRGI 326
Query 819 SPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ + +P A L + C +P +RP F +IL+ L L+ L
Sbjct 327 DCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLR 386
Query 876 DVLTVNPDSPASDP 889
++ + S
Sbjct 387 EMPRDSFHSMQEGW 400
>sp|Q9SIB6|PBL6_ARATH Probable serine/threonine-protein kinase
PBL6 OS=Arabidopsis thaliana OX=3702 GN=PBL6 PE=2 SV=1
Length=424
Score = 249 bits (635), Expect = 1e-71, Method: Composition-based stats.
Identities = 77/287 (27%), Positives = 127/287 (44%), Gaps = 18/287 (6%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
K LGEG FGKV + N ++VA+K L + G Q + E+ L
Sbjct 97 NFKSDCFLGEGGFGKVYKGFIEKIN----QVVAIKQLDRN-GAQGIREFVVEVLTLSLAD 151
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEG 1010
H +++K G C + ++ LV EY+PLGSL ++L ++ + + A G
Sbjct 152 HPNLVKLIGFCAEGVQR--LLVYEYMPLGSLDNHLHDLPSGKNPLAWNTRMKIAAGAARG 209
Query 1011 MAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH I+RDL N+L+D K+ DFGLAK P G E + V +
Sbjct 210 LEYLHDTMKPPVIYRDLKCSNILIDEGYHAKLSDFGLAKVGPRGSETH-VSTRVMGTYGY 268
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQMTVLR-LT 1125
AP+ + + SDV+SFGV L EL+T + + T+ L+ A +
Sbjct 269 CAPDYALTGQLTFKSDVYSFGVVLLELITGRKAYDNTRTRNHQSLVEWANPLFKDRKNFK 328
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
++++ P + + + C + + S RP +++ L +
Sbjct 329 KMVDPLLEGDYPVRGLYQALAIAAMCVQEQPSMRPVIADVVMALDHL 375
Score = 221 bits (562), Expect = 9e-62, Method: Composition-based stats.
Identities = 70/345 (20%), Positives = 115/345 (33%), Gaps = 66/345 (19%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+T +LS V LG+G VY+G +
Sbjct 82 KAQTFTFEELS---VSTGNFKSDCFLGEGGFGKVYKGFIEKINQ---------------- 122
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
V +K LD + F +S H +L + G C G + ++V EY
Sbjct 123 --------VVAIKQLDRNGAQGIREFVVEVLTLSLADHPNLVKLIGFCAEGVQRLLVYEY 174
Query 690 VEHGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLA 743
+ G LD L G P+AW +M +A A L YL + +++ ++ NIL+
Sbjct 175 MPLGSLDNHLHDLPSGKNPLAWNTRMKIAAGAARGLEYLHDTMKPPVIYRDLKCSNILID 234
Query 744 RLGLAEGTSPFIKLSDPGVGL-GALSREERV-----ERIPWLAPECLPGGANSLSTAMDK 797
KLSD G+ G E V + AP+ G L+ D
Sbjct 235 E-------GYHAKLSDFGLAKVGPRGSETHVSTRVMGTYGYCAPDYALTG--QLTFKSDV 285
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQ------RQHRLPEPSCPQLA--------- 842
+ FG LLE+ +A +R+ + + + + P L
Sbjct 286 YSFGVVLLELITGRKAYDNTRTRNHQSLVEWANPLFKDRKNFKKMVDPLLEGDYPVRGLY 345
Query 843 ---TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884
+ + C+ +P+ RP ++ L L D+
Sbjct 346 QALAIAAMCVQEQPSMRPVIADVVMALDHLASSKYDRSHRQKQDN 390
>sp|Q7T6X2|YR826_MIMIV Putative serine/threonine-protein kinase/receptor
R826 OS=Acanthamoeba polyphaga mimivirus OX=212035
GN=MIMI_R826 PE=3 SV=2
Length=1657
Score = 266 bits (681), Expect = 1e-71, Method: Composition-based stats.
Identities = 80/326 (25%), Positives = 135/326 (41%), Gaps = 33/326 (10%)
Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911
+ S + Q H + S V + +K +G G +G V
Sbjct 1354 DMDTDNSTFSARVPHQAYQYHAAIENNERYLTSAGLCSWVINYDEIKMGEQIGLGSYGVV 1413
Query 912 SLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970
+ + VA+K +K H G ++EI L+ L+H +II G +
Sbjct 1414 YRGKWKNVD------VAIKKFIKQKIDENHLLGIREEIAFLKKLHHPNIITMVGASLKK- 1466
Query 971 EKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHA--QHYIHRDLAA 1026
++ +V EY+ G+LRD + + Q + I +G++YLH+ IHRD+
Sbjct 1467 -PNICIVTEYMAKGNLRDAMRTCTPKLEWHQKIKILVNIAKGISYLHSFDPPIIHRDIKP 1525
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
N+L+D + VKI DFG A+ E R W APE ++ + DV+S
Sbjct 1526 SNILIDENWNVKIADFGFARIKEENAIMTR-----CGTPCWTAPEIIRNDIYDEKVDVFS 1580
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
FG+ ++E+LT + +++T + R P CP E
Sbjct 1581 FGIVMWEVLTCKEPF---------------IGANFMKITMDILEDVRPKIPQDCPEEFAK 1625
Query 1147 LMKNCWETEASFRPTFENLIPILKTV 1172
LM+ CW +++ RPT +++I +L
Sbjct 1626 LMRKCWHAKSTKRPTMDDVIIVLAKF 1651
Score = 240 bits (612), Expect = 4e-63, Method: Composition-based stats.
Identities = 79/295 (27%), Positives = 120/295 (41%), Gaps = 35/295 (12%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG--PQHRSGWKQE 947
L+ LG G FG+V + G VAVK + D +K E
Sbjct 779 WEIDFHELELGEQLGTGAFGEVHKGTWR------GTEVAVKMISPDKTITKDIERNFKDE 832
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFA 1004
+ ++ TL H +++ + + +VME++ LGSL D L I A + A
Sbjct 833 VRVMTTLRHPNVVLFMAASTKP--PKMCIVMEFMALGSLHDLLKNELIPDIPFALKVKIA 890
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
Q +GM +LH+ HRDL + N+LLD VK+ DFGL K + E
Sbjct 891 YQASKGMHFLHSSGITHRDLKSLNLLLDIKWNVKVSDFGLTKFKSDVKSINP--EKFAGT 948
Query 1065 VFWYAPECLKEYK--FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
+ W APE L E + Y SDV+SFG+ ++EL+T G
Sbjct 949 IQWTAPEILSEDREVDYILSDVYSFGIIMWELITRDQPYF--------------GMSPAA 994
Query 1123 RLTELLERGERLPRPD----KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
++ R D + E L+ +CW + + RPTF ++ L +
Sbjct 995 IAVSVIRDNYRPVISDQLRSEVAPEYIELLTSCWHFDPTIRPTFLEIMTRLSNLM 1049
Score = 231 bits (590), Expect = 2e-60, Method: Composition-based stats.
Identities = 70/359 (19%), Positives = 123/359 (34%), Gaps = 65/359 (18%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
+D E+ LG G V++G R V
Sbjct 777 DDWEIDFHELELGEQLGTGAFGEVHKGTWRG--------------------------TEV 810
Query 640 VLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+K++ P DI F + +M+ + H ++ + P+ +V E++ G L
Sbjct 811 AVKMISPDKTITKDIERNFKDEVRVMTTLRHPNVVLFMAASTKPPKMCIVMEFMALGSLH 870
Query 697 VWLRRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
L+ E +P A K+ +A Q + + +L + + H ++ N+LL +
Sbjct 871 DLLKNELIPDIPFALKVKIAYQASKGMHFLHSSGITHRDLKSLNLLLD-------IKWNV 923
Query 756 KLSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K+SD G+ +++ E+ I W APE L D + FG + E+
Sbjct 924 KVSDFGLTKFKSDVKSINPEKFAGTIQWTAPEILSEDREVDYILSDVYSFGIIMWELITR 983
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSC-------PQLATLTSQCLTYEPTQRPSFRTIL 863
+ P SP+ R + P S P+ L + C ++PT RP+F I+
Sbjct 984 -DQPYFGMSPAAIAVSVIRDNYRPVISDQLRSEVAPEYIELLTSCWHFDPTIRPTFLEIM 1042
Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922
L+ L FGKV + + T+
Sbjct 1043 TRLSNL---------------MGDSGMTGMSSSSSNSSKFDYNSFGKVQQFAINRTDPD 1086
Score = 226 bits (576), Expect = 9e-59, Method: Composition-based stats.
Identities = 53/298 (18%), Positives = 107/298 (36%), Gaps = 42/298 (14%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
R L + L ++ EI +G G+ VY G+ +
Sbjct 1382 RYLTSAGLCSWVINYDEIKMGEQIGLGSYGVVYRGKWKN--------------------- 1420
Query 632 DRGQELRVVLKVLDPSHHDIALAF--YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
+ V +K D E + + ++ H ++ + G ++ P +VTEY
Sbjct 1421 -----VDVAIKKFIKQKIDENHLLGIREEIAFLKKLHHPNIITMVGASLKKPNICIVTEY 1475
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGL 747
+ G L +R + K+ + +A +SYL + ++H ++ NIL+
Sbjct 1476 MAKGNLRDAMRTCTPKLEWHQKIKILVNIAKGISYLHSFDPPIIHRDIKPSNILIDE--- 1532
Query 748 AEGTSPFIKLSDPGVGLGALSRE--ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ +K++D G R W APE + +D + FG +
Sbjct 1533 ----NWNVKIADFGFARIKEENAIMTRCGTPCWTAPEIIRNDI--YDEKVDVFSFGIVMW 1586
Query 806 EICFDGEAPLQSRSPSEKEHFYQR-QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
E+ E + + + + ++P+ + A L +C + T+RP+ +
Sbjct 1587 EVLTCKEPFIGANFMKITMDILEDVRPKIPQDCPEEFAKLMRKCWHAKSTKRPTMDDV 1644
>sp|Q78DX7|ROS1_MOUSE Proto-oncogene tyrosine-protein kinase ROS
OS=Mus musculus OX=10090 GN=Ros1 PE=1 SV=1
Length=2340
Score = 267 bits (682), Expect = 1e-71, Method: Composition-based stats.
Identities = 95/291 (33%), Positives = 139/291 (48%), Gaps = 32/291 (11%)
Query 907 HFGKVSLYC-YDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG 964
FG+V D G+GE VAVK LK Q + + +E ++ H +I+K G
Sbjct 1948 AFGEVYEGTAIDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLG 2007
Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYLPRH--------SIGLAQLLLFAQQICEGMAYLHA 1016
C + +++E + G L YL + S+ L L+ I +G YL
Sbjct 2008 VCLLGEPQ--YIILELMEGGDLLSYLRKARGTTFHGPSLTLLDLVELCVDISKGCVYLEQ 2065
Query 1017 QHYIHRDLAARNVLL-----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
H+IHRDLAARN L+ + R+VKIGDFGLA+ + + ++YYR R +G PV W APE
Sbjct 2066 MHFIHRDLAARNCLVSVKDYTSPRVVKIGDFGLAREIYK-NDYYRKRGEGLLPVRWMAPE 2124
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
L + F SDVWSFG+ ++E+LT L + L + ++ G
Sbjct 2125 NLMDGIFTSQSDVWSFGILVWEILT--------------LGHQPYPAHSNLDVLNYVQAG 2170
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182
RL P CP ++++LM CW E RPTF N+ L+ +
Sbjct 2171 GRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHNIQNQLQLFRNVFLNNVSH 2221
Score = 248 bits (633), Expect = 2e-65, Method: Composition-based stats.
Identities = 76/298 (26%), Positives = 123/298 (41%), Gaps = 39/298 (13%)
Query 599 TRTNVYEGR-LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFY 656
VYEG + + G G E++V +K L D F
Sbjct 1948 AFGEVYEGTAIDILGVGSG-------------------EIKVAVKTLKKGSTDQEKIEFL 1988
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG------HVPMAW 710
+ A LMS+ +H ++ GVC+ G ++ E +E G L +LR+ RG + +
Sbjct 1989 KEAHLMSKFNHPNILKQLGVCLLGEPQYIILELMEGGDLLSYLRKARGTTFHGPSLTLLD 2048
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ + ++ YLE + +H ++ RN L++ + +K+ D G+ +
Sbjct 2049 LVELCVDISKGCVYLEQMHFIHRDLAARNCLVSVK--DYTSPRVVKIGDFGLAREIYKND 2106
Query 771 ERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+R + W+APE L G ++ D W FG + EI G P + S +
Sbjct 2107 YYRKRGEGLLPVRWMAPENLMDGI--FTSQSDVWSFGILVWEILTLGHQPYPAHSNLDVL 2164
Query 825 HFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880
++ Q RL P +CP L L SQC EP QRP+F I L + L +V
Sbjct 2165 NYVQAGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHNIQNQLQLFRNVFLNNVSHC 2222
>sp|F4JPX3|PBL20_ARATH Probable serine/threonine-protein kinase
PBL20 OS=Arabidopsis thaliana OX=3702 GN=PBL20 PE=3 SV=1
Length=388
Score = 247 bits (631), Expect = 2e-71, Method: Composition-based stats.
Identities = 93/386 (24%), Positives = 146/386 (38%), Gaps = 21/386 (5%)
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTI 862
F + P SR EKE R + S P+L T T P PS +I
Sbjct 3 CLFLFMSKKPK-SRGNMEKEKKNIRGREFLQKSAPELTTRKTTLSFNLPTPRSLPSPTSI 61
Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD----P 918
+ N + + +GEG FG V +
Sbjct 62 KD-----LYTDREQNQNQNLRVFSFKELSDATCEFSRKLKIGEGGFGSVYKATINNPTVG 116
Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978
+ + VAVK L H+ W E+ L + H ++++ G C + E+ LV
Sbjct 117 DSHSSPLTVAVKKLNRQSLQGHKQ-WLAEVHFLGVVNHPNVVRLLGYCSEDRER--LLVY 173
Query 979 EYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035
E + SL D+L ++ Q L +G+AYLH I+RD + NVLL+ +
Sbjct 174 ELMSNRSLEDHLFTLRTLTLSWKQRLEIMLGAAQGLAYLHEIQVIYRDFKSSNVLLNEEF 233
Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
K+ DFGLA+ PEG + V + APE + DV+SFGV LYE++
Sbjct 234 HPKLSDFGLAREGPEGDNTH-VTTARVGTDGYAAPEYVITGHLKTHCDVYSFGVVLYEII 292
Query 1096 THCDSSQ--SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
T + + P + L + + + R +++ P V L +C
Sbjct 293 TGRRTLERMKPLAEQKLLEWVKKYPINSKRFKMIVDSKLCNKYPIAMVRRVAKLADHCVN 352
Query 1154 TEASFRPTFENLIPILKTVHEKYQGQ 1179
RPT ++ L + E+ +
Sbjct 353 KIDKERPTMAFVVESLTNIIEESNSE 378
Score = 220 bits (560), Expect = 5e-62, Method: Composition-based stats.
Identities = 65/340 (19%), Positives = 116/340 (34%), Gaps = 39/340 (11%)
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRC-CLPQPGETSNLII 563
F ++ +E ++ L + R F+L LP P +L
Sbjct 7 FMSKKPKSRGNMEKEKKNIRGREFLQKSAPELTTRKTTLSFNLPTPRSLPSPTSIKDLYT 66
Query 564 MRGARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
R + NL SF + E ++ +G+G +VY+ + GD +
Sbjct 67 DREQNQNQ---NLRVFSFKELSDATCEFSRKLKIGEGGFGSVYKATINNPTVGDSHSSPL 123
Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
V +K L+ + + V+H ++ + G C
Sbjct 124 ----------------TVAVKKLNRQSLQGHKQWLAEVHFLGVVNHPNVVRLLGYCSEDR 167
Query 682 ENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNI 740
E ++V E + + L+ L R + ++ + A L+YL +++ + N+
Sbjct 168 ERLLVYELMSNRSLEDHLFTLRTLTLSWKQRLEIMLGAAQGLAYLHEIQVIYRDFKSSNV 227
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTA 794
LL KLSD G+ + RV + APE + G L T
Sbjct 228 LLNEE-------FHPKLSDFGLAREGPEGDNTHVTTARVGTDGYAAPEYVITG--HLKTH 278
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834
D + FG L EI G L+ P ++ + + P
Sbjct 279 CDVYSFGVVLYEII-TGRRTLERMKPLAEQKLLEWVKKYP 317
>sp|Q3EDL4|Y1154_ARATH Probable serine/threonine-protein kinase
At1g01540 OS=Arabidopsis thaliana OX=3702 GN=At1g01540 PE=1
SV=2
Length=472
Score = 250 bits (638), Expect = 2e-71, Method: Composition-based stats.
Identities = 68/282 (24%), Positives = 123/282 (44%), Gaps = 19/282 (7%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+ +GEG +G V G VAVK L + G Q +K E++++ + H+
Sbjct 155 CEENVIGEGGYGIVYRGIL-----TDGTKVAVKNLLNNRG-QAEKEFKVEVEVIGRVRHK 208
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQICEGMA 1012
++++ G C + + LV ++V G+L ++ + + + +G+A
Sbjct 209 NLVRLLGYCVEGAYR--MLVYDFVDNGNLEQWIHGDVGDVSPLTWDIRMNIILGMAKGLA 266
Query 1013 YLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH +HRD+ + N+LLD K+ DFGLAK + Y R + A
Sbjct 267 YLHEGLEPKVVHRDIKSSNILLDRQWNAKVSDFGLAKLLGSESSYVTTR--VMGTFGYVA 324
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE SD++SFG+ + E++T + S P L+ + + R E++
Sbjct 325 PEYACTGMLNEKSDIYSFGILIMEIITGRNPVDYSRPQGETNLVDWLKSMVGNRRSEEVV 384
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ P K V + C + +A+ RP ++I +L+
Sbjct 385 DPKIPEPPSSKALKRVLLVALRCVDPDANKRPKMGHIIHMLE 426
Score = 218 bits (555), Expect = 2e-60, Method: Composition-based stats.
Identities = 62/312 (20%), Positives = 113/312 (36%), Gaps = 64/312 (21%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
+ + + +G+G VY G L +V +K
Sbjct 148 EAATNGLCEENVIGEGGYGIVYRGILTDG-------------------------TKVAVK 182
Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
L + F ++ +V H +L + G CV G ++V ++V++G L+ W+ +
Sbjct 183 NLLNNRGQAEKEFKVEVEVIGRVRHKNLVRLLGYCVEGAYRMLVYDFVDNGNLEQWIHGD 242
Query 703 RGHV-PMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
G V P+ W +M + +A L+YL +VH ++ NILL R K
Sbjct 243 VGDVSPLTWDIRMNIILGMAKGLAYLHEGLEPKVVHRDIKSSNILLDRQ-------WNAK 295
Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
+SD G+ + + ++APE G L+ D + FG ++EI G
Sbjct 296 VSDFGLAKLLGSESSYVTTRVMGTFGYVAPEYACTGM--LNEKSDIYSFGILIMEII-TG 352
Query 812 EAPLQSRSPSEKEHFYQR------QHRLPEPSCPQLAT------------LTSQCLTYEP 853
P+ P + + R E P++ + +C+ +
Sbjct 353 RNPVDYSRPQGETNLVDWLKSMVGNRRSEEVVDPKIPEPPSSKALKRVLLVALRCVDPDA 412
Query 854 TQRPSFRTILRD 865
+RP I+
Sbjct 413 NKRPKMGHIIHM 424
>sp|Q93YN1|CRPK1_ARATH Cold-responsive protein kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=CRPK1 PE=1 SV=1
Length=390
Score = 247 bits (631), Expect = 2e-71, Method: Composition-based stats.
Identities = 72/297 (24%), Positives = 124/297 (42%), Gaps = 21/297 (7%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
+GEG FG V C G++ A+K L A+ Q +
Sbjct 29 YKYREIRQATDDFSAENKIGEGGFGSVYKGCLK-----DGKLAAIKVLSAE-SRQGVKEF 82
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSIGL 997
EI+++ + HE+++K GCC + + LV ++ SL L
Sbjct 83 LTEINVISEIQHENLVKLYGCCVEGNHR--ILVYNFLENNSLDKTLLAGGYTRSGIQFDW 140
Query 998 AQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ + +G+A+LH + H IHRD+ A N+LLD KI DFGLA+ +P +
Sbjct 141 SSRANICVGVAKGLAFLHEEVRPHIIHRDIKASNILLDKYLSPKISDFGLARLMPPNMTH 200
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIG 1113
R G + + APE + +D++SFGV L E+++ + + PT++ L+
Sbjct 201 VSTRVAG--TIGYLAPEYAVRGQLTRKADIYSFGVLLMEIVSGRSNKNTRLPTEYQYLLE 258
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
A L +L++ G + C + C + RP+ ++ +L
Sbjct 259 RAWELYERNELVDLVDSGLNGVFDAEEACRYLKIGLLCTQDSPKLRPSMSTVVRLLT 315
Score = 217 bits (553), Expect = 6e-61, Method: Composition-based stats.
Identities = 61/291 (21%), Positives = 112/291 (38%), Gaps = 52/291 (18%)
Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
N+ + + + + + +G+G +VY+G L+
Sbjct 25 NVKIYKYREIRQATDDFSAENKIGEGGFGSVYKGCLKDGK-------------------- 64
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
+KVL F +++S++ H +L ++G CV G I+V ++E+
Sbjct 65 -----LAAIKVLSAESRQGVKEFLTEINVISEIQHENLVKLYGCCVEGNHRILVYNFLEN 119
Query 693 GPLDVWLR-----RERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744
LD L R + + + +A L++L + +++H ++ NILL +
Sbjct 120 NSLDKTLLAGGYTRSGIQFDWSSRANICVGVAKGLAFLHEEVRPHIIHRDIKASNILLDK 179
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWG 799
K+SD G+ V I +LAPE G L+ D +
Sbjct 180 YLSP-------KISDFGLARLMPPNMTHVSTRVAGTIGYLAPEYAVRG--QLTRKADIYS 230
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLT 850
FG L+EI G + +R P+E ++ +R L E + +L L L
Sbjct 231 FGVLLMEIVS-GRSNKNTRLPTEYQYLLERAWELYERN--ELVDLVDSGLN 278
>sp|Q9LZU4|CRK4_ARATH Cysteine-rich receptor-like protein kinase
4 OS=Arabidopsis thaliana OX=3702 GN=CRK4 PE=2 SV=1
Length=676
Score = 256 bits (653), Expect = 2e-71, Method: Composition-based stats.
Identities = 76/285 (27%), Positives = 121/285 (42%), Gaps = 19/285 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+ LG+G FG+V + +G VAVK L G R + E+ ++ L H
Sbjct 351 FCETNKLGQGGFGEVYKGIF-----PSGVQVAVKRLSKTSGQGERE-FANEVIVVAKLQH 404
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMA 1012
++++ G C ++ E+ LV E+VP SL ++ + + + I G+
Sbjct 405 RNLVRLLGFCLERDER--ILVYEFVPNKSLDYFIFDSTMQSLLDWTRRYKIIGGIARGIL 462
Query 1013 YLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH IHRDL A N+LL +D KI DFG+A+ R + +
Sbjct 463 YLHQDSRLTIIHRDLKAGNILLGDDMNAKIADFGMARIFGMDQTEANTRR-IVGTYGYMS 521
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTE 1126
PE +F SDV+SFGV + E+++ +S Q T L+ + E
Sbjct 522 PEYAMYGQFSMKSDVYSFGVLVLEIISGKKNSNVYQMDGTSAGNLVTYTWRLWSNGSPLE 581
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
L++ R H+ C + EA RPT ++ +L T
Sbjct 582 LVDPSFRDNYRINEVSRCIHIALLCVQEEAEDRPTMSAIVQMLTT 626
Score = 230 bits (586), Expect = 2e-62, Method: Composition-based stats.
Identities = 57/325 (18%), Positives = 110/325 (34%), Gaps = 66/325 (20%)
Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
T Q F ++ + + + LGQG VY+G
Sbjct 333 TAGSLQFDFKAIEAATNKFCETNKLGQGGFGEVYKGI----------------------- 369
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
++V +K L + F +++++ H +L + G C+ E I+V E+V
Sbjct 370 --FPSGVQVAVKRLSKTSGQGEREFANEVIVVAKLQHRNLVRLLGFCLERDERILVYEFV 427
Query 691 EHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745
+ LD ++ + W + + +A + YL + ++H ++ NILL
Sbjct 428 PNKSLDYFIFDSTMQSLLDWTRRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNILL--- 484
Query 746 GLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
G K++D G+ + V +++PE G S D +
Sbjct 485 ----GDDMNAKIADFGMARIFGMDQTEANTRRIVGTYGYMSPEYAMYG--QFSMKSDVYS 538
Query 800 FGATLLEICFDGE-APLQSRSPSEKEHFYQRQHRLPEPSCP------------------Q 840
FG +LEI + + + + + RL P +
Sbjct 539 FGVLVLEIISGKKNSNVYQMDGTSAGNLVTYTWRLWSNGSPLELVDPSFRDNYRINEVSR 598
Query 841 LATLTSQCLTYEPTQRPSFRTILRD 865
+ C+ E RP+ I++
Sbjct 599 CIHIALLCVQEEAEDRPTMSAIVQM 623
>sp|P80192|M3K9_HUMAN Mitogen-activated protein kinase kinase
kinase 9 OS=Homo sapiens OX=9606 GN=MAP3K9 PE=1 SV=3
Length=1104
Score = 263 bits (673), Expect = 2e-71, Method: Composition-based stats.
Identities = 93/293 (32%), Positives = 135/293 (46%), Gaps = 41/293 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP---QHRSGWKQEIDILRTLYHEHI 959
+G G FGKV + G+ VAVKA + D Q +QE + L H +I
Sbjct 150 IGIGGFGKVYRAFWI------GDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPNI 203
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
I +G C E +L LVME+ G L L I L+ +A QI GM YLH +
Sbjct 204 IALRGVCLK--EPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIARGMNYLHDEAI 261
Query 1018 -HYIHRDLAARNVLL-------D-NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
IHRDL + N+L+ D +++++KI DFGLA+ + + W
Sbjct 262 VPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLAR-----EWHRTTKMSAAGTYAWM 316
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
APE ++ F SDVWS+GV L+ELLT P + ++ + +A G +
Sbjct 317 APEVIRASMFSKGSDVWSYGVLLWELLTG-----EVPFRGIDGLAVAYG---------VA 362
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
LP P CP LM++CW + RP+F N++ L T+ E + P
Sbjct 363 MNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNILDQLTTIEESGFFEMP 415
Score = 236 bits (602), Expect = 2e-62, Method: Composition-based stats.
Identities = 89/483 (18%), Positives = 168/483 (35%), Gaps = 75/483 (16%)
Query 513 AFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPR 572
+ G + ++ L +GD+ + + SN + R A +S
Sbjct 62 EYEAAGEDELTLRLGDVVEVLSKDSQVSGDEGWWTGQLNQRVGIFPSNYVTPRSAFSSRC 121
Query 573 TLN------LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+ +D E+T +G G VY +
Sbjct 122 QPGGEDPSCYPPIQLLEIDFAELTLEEIIGIGGFGKVYRAFWIGD--------------- 166
Query 627 LVPGRDRGQELRVVLKVL----DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
V +K D + A L + + H ++ + GVC++ P
Sbjct 167 -----------EVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPN 215
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRN 739
+V E+ GPL+ L +R +P + A Q+A ++YL ++ ++H ++ N
Sbjct 216 LCLVMEFARGGPLNRVLSGKR--IPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSN 273
Query 740 IL-LARLGLAEGTSPFIKLSDPGVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMD 796
IL L ++ + ++ +K++D G+ ++ W+APE + A+ S D
Sbjct 274 ILILQKVENGDLSNKILKITDFGLAREWHRTTKMSAAGTYAWMAPEVIR--ASMFSKGSD 331
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEP 853
W +G L E+ GE P + + + +P A L C +P
Sbjct 332 VWSYGVLLWELL-TGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDP 390
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
RPSF IL LT ++ ++ + + + ++R
Sbjct 391 HSRPSFTNILDQLTTIEESGFFEMPKDSFHCLQDNWKHEIQEMFDQLRA----------- 439
Query 914 YCYDPTNDGTGEM----VAV--KALKADCGPQHRSGWKQEIDIL-RTLYHEHIIKYKGCC 966
T E A+ K + + + ++EIDIL R L +II C
Sbjct 440 ---KEKELRTWEEELTRAALQQKNQEELLRRREQELAEREIDILEREL---NII-IHQLC 492
Query 967 EDQ 969
+++
Sbjct 493 QEK 495
>sp|Q63132|ROS1_RAT Proto-oncogene tyrosine-protein kinase ROS
OS=Rattus norvegicus OX=10116 GN=Ros1 PE=2 SV=1
Length=2338
Score = 266 bits (681), Expect = 2e-71, Method: Composition-based stats.
Identities = 96/283 (34%), Positives = 138/283 (49%), Gaps = 32/283 (11%)
Query 907 HFGKVSLYC-YDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG 964
FG+V D G+GE VAVK LK Q + + +E ++ H +I+K G
Sbjct 1947 AFGEVYEGTAVDILGRGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLG 2006
Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------IGLAQLLLFAQQICEGMAYLHA 1016
C + +++E + G L YL + + LA L+ I +G YL
Sbjct 2007 VCLLSEPQ--YIILELMEGGDLLSYLRKARGTTLSGPLLTLADLVELCVDISKGCVYLEQ 2064
Query 1017 QHYIHRDLAARNVLL-----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
H+IHRDLAARN L+ + R+VKIGDFGLA+ + + H+YYR R +G PV W APE
Sbjct 2065 MHFIHRDLAARNCLVSVKDYTSPRVVKIGDFGLAREIYK-HDYYRKRGEGLLPVRWMAPE 2123
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
L + F SDVWSFG+ ++E+LT L + L + ++ G
Sbjct 2124 NLMDGIFTSQSDVWSFGILVWEILT--------------LGHQPYPAHSNLDVLNYVQAG 2169
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
RL P CP ++++LM CW E RPTF N+ L+
Sbjct 2170 GRLEPPRNCPDDLWNLMFRCWAQEPDQRPTFYNIQDQLQLFRN 2212
Score = 246 bits (627), Expect = 7e-65, Method: Composition-based stats.
Identities = 75/297 (25%), Positives = 123/297 (41%), Gaps = 37/297 (12%)
Query 599 TRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYE 657
VYEG + GR G E++V +K L D F +
Sbjct 1947 AFGEVYEGT-----------------AVDILGRGSG-EIKVAVKTLKKGSTDQEKIEFLK 1988
Query 658 TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH------VPMAWK 711
A LMS+ +H ++ GVC+ ++ E +E G L +LR+ RG + +A
Sbjct 1989 EAHLMSKFNHPNILKQLGVCLLSEPQYIILELMEGGDLLSYLRKARGTTLSGPLLTLADL 2048
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771
+ + ++ YLE + +H ++ RN L++ + +K+ D G+ +
Sbjct 2049 VELCVDISKGCVYLEQMHFIHRDLAARNCLVSVK--DYTSPRVVKIGDFGLAREIYKHDY 2106
Query 772 RVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
+R + W+APE L G ++ D W FG + EI G P + S + +
Sbjct 2107 YRKRGEGLLPVRWMAPENLMDGI--FTSQSDVWSFGILVWEILTLGHQPYPAHSNLDVLN 2164
Query 826 FYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880
+ Q RL P +CP L L +C EP QRP+F I L + +L +V
Sbjct 2165 YVQAGGRLEPPRNCPDDLWNLMFRCWAQEPDQRPTFYNIQDQLQLFRNVSLNNVSHC 2221
>sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens
OX=9606 GN=TNK2 PE=1 SV=3
Length=1038
Score = 262 bits (670), Expect = 2e-71, Method: Composition-based stats.
Identities = 106/272 (39%), Positives = 151/272 (56%), Gaps = 21/272 (8%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG V +D + T VAVK LK D P+ + +E++ + +L H ++
Sbjct 131 KLGDGSFGVVRRGEWDAPSGKT-VSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNL 189
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQ 1017
I+ G +++V E PLGSL D L +H L L +A Q+ EGM YL ++
Sbjct 190 IRLYGVVLTP---PMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESK 246
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+IHRDLAARN+LL LVKIGDFGL +A+P+ ++Y ++E P W APE LK
Sbjct 247 RFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRT 306
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F +ASD W FGVTL+E+ T+ IG+ Q+ L ++ + GERLPRP
Sbjct 307 FSHASDTWMFGVTLWEMFTYGQEP---------WIGLNGSQI----LHKIDKEGERLPRP 353
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ CP ++Y++M CW + RPTF L L
Sbjct 354 EDCPQDIYNVMVQCWAHKPEDRPTFVALRDFL 385
Score = 233 bits (593), Expect = 1e-61, Method: Composition-based stats.
Identities = 87/353 (25%), Positives = 136/353 (39%), Gaps = 54/353 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ +K++ L LG G+ V G G+ + V +K
Sbjct 121 IGEKDLRLLEKLGDGSFGVVRRGEW---------------------DAPSGKTVSVAVKC 159
Query 644 LDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
L P S + F + M + H +L ++GV + P MVTE G L LR
Sbjct 160 LKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLT-PPMKMVTELAPLGSLLDRLR 218
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ +GH + A Q+A + YLE+K +H ++ RN+LLA T +K+ D
Sbjct 219 KHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLA-------TRDLVKIGDF 271
Query 761 GVGLG-------ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ + +E R W APE L + S A D W FG TL E+ G+
Sbjct 272 GLMRALPQNDDHYVMQEHRKVPFAWCAPESLKT--RTFSHASDTWMFGVTLWEMFTYGQE 329
Query 814 PLQSRSPSEKEH-FYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P + S+ H + RLP P CPQ + + QC ++P RP+F + L Q
Sbjct 330 PWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQ 389
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923
P ++ + ++ G+ Y + N T
Sbjct 390 PTDMRALQDFEEPDKLHIQMNDVITVIE----------GRAENYWWRGQNTRT 432
>sp|Q1RMT8|IRAK4_BOVIN Interleukin-1 receptor-associated kinase
4 OS=Bos taurus OX=9913 GN=IRAK4 PE=2 SV=1
Length=461
Score = 249 bits (636), Expect = 2e-71, Method: Composition-based stats.
Identities = 77/312 (25%), Positives = 128/312 (41%), Gaps = 20/312 (6%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
L+ + + + +GEG FG V VA
Sbjct 159 LEFSDTRFHSFSFFELKDVTNNFDERPISVGGNKMGEGGFGVVYKGYV------NNRTVA 212
Query 929 VKALKAD---CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
VK L A + + + QEI ++ HE++++ G D + L LV Y+P GS
Sbjct 213 VKKLAAMVDISTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDD--LCLVYVYMPNGS 270
Query 986 LRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
L D L + AQ G++YLH H+IHRD+ + N+LLD D KI D
Sbjct 271 LLDRLSCLDGTPPLSWNMRCKIAQGAANGLSYLHENHHIHRDIKSANILLDEDFTAKISD 330
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLA+A + + + + APE L+ SD++SFGV L E++T +
Sbjct 331 FGLARASEKFAQTVMTSRIVGTTA-YMAPEALRGE-ITPKSDIYSFGVVLLEIITGLPAV 388
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE-VYHLMKNCWETEASFRP 1160
L L + + + + ++R ++ D E +Y + C + + RP
Sbjct 389 DEHREPQLLLDIKEEIEDEEKTIEDYVDR--KMNDIDSTSIETMYSVASQCLHEKKNKRP 446
Query 1161 TFENLIPILKTV 1172
+ + +L+ +
Sbjct 447 DIKKVQQLLEEM 458
Score = 223 bits (567), Expect = 4e-62, Method: Composition-based stats.
Identities = 70/352 (20%), Positives = 128/352 (36%), Gaps = 76/352 (22%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQ-------------LSHLGQGTRTNVY 604
N ++ + +L S FH E+ + +G+G VY
Sbjct 143 EQNYVLPDSSSPENTSLEFSDTRFHSFSFFELKDVTNNFDERPISVGGNKMGEGGFGVVY 202
Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL----DPSHHDIALAFYETAS 660
+G + V +K L D S ++ F +
Sbjct 203 KGYVNNR--------------------------TVAVKKLAAMVDISTEELKQQFDQEIK 236
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQL 718
+M++ H +L + G G + +V Y+ +G L L G P++W + +AQ
Sbjct 237 VMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWNMRCKIAQGA 296
Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA------LSREER 772
A+ LSYL + +H ++ NILL K+SD G+ + +
Sbjct 297 ANGLSYLHENHHIHRDIKSANILLDE-------DFTAKISDFGLARASEKFAQTVMTSRI 349
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS----------- 821
V ++APE L G ++ D + FG LLEI A + R P
Sbjct 350 VGTTAYMAPEALRG---EITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIED 406
Query 822 ----EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+++ ++ + + S + ++ SQCL + +RP + + + L +
Sbjct 407 EEKTIEDYVDRKMNDIDSTSIETMYSVASQCLHEKKNKRPDIKKVQQLLEEM 458
>sp|Q15303|ERBB4_HUMAN Receptor tyrosine-protein kinase erbB-4
OS=Homo sapiens OX=9606 GN=ERBB4 PE=1 SV=1
Length=1308
Score = 265 bits (676), Expect = 3e-71, Method: Composition-based stats.
Identities = 98/272 (36%), Positives = 140/272 (51%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + VA+K L GP+ + E I+ ++ H H+++
Sbjct 724 LGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRL 783
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C +QLV + +P G L +Y+ H IG LL + QI +GM YL + +
Sbjct 784 LGVCLSPT---IQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV 840
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ + VKI DFGLA+ + EG E + G P+ W A EC+ KF +
Sbjct 841 HRDLAARNVLVKSPNHVKITDFGLARLL-EGDEKEYNADGGKMPIKWMALECIHYRKFTH 899
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T G + + +LLE+GERLP+P C
Sbjct 900 QSDVWSYGVTIWELMTFG--------------GKPYDGIPTREIPDLLEKGERLPQPPIC 945
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW +A RP F+ L +
Sbjct 946 TIDVYMVMVKCWMIDADSRPKFKELAAEFSRM 977
Score = 241 bits (615), Expect = 1e-63, Method: Composition-based stats.
Identities = 67/338 (20%), Positives = 131/338 (39%), Gaps = 39/338 (12%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P +Q + + E+ ++ LG G VY+G EG
Sbjct 699 TPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETV-------------- 744
Query 630 GRDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ V +K+L+ + + F + A +M+ + H HL + GVC+ P +VT+
Sbjct 745 ------KIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCL-SPTIQLVTQ 797
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ HG L ++ + ++ + Q+A + YLE + LVH ++ RN+L+
Sbjct 798 LMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPN-- 855
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+K++D G+ + + I W+A EC+ + D W +G
Sbjct 856 -----HVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIH--YRKFTHQSDVWSYGV 908
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860
T+ E+ G P E ++ RLP+P + + +C + RP F+
Sbjct 909 TIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFK 968
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898
+ + +R+ ++ D K +
Sbjct 969 ELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQN 1006
>sp|Q9YI66|TYRO3_DANRE Tyrosine-protein kinase receptor TYRO3
OS=Danio rerio OX=7955 GN=tyro3 PE=2 SV=1
Length=874
Score = 259 bits (662), Expect = 3e-71, Method: Composition-based stats.
Identities = 94/337 (28%), Positives = 150/337 (45%), Gaps = 28/337 (8%)
Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVS 912
P + R+ R L L + + + +R L R LG+G FG V
Sbjct 453 PVSFTAARSFNRQFPELPESTLDSLGINSDLKAKLQDVLIFERLLTLGRMLGKGEFGSVR 512
Query 913 LYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
N+ +G+ VAVK LK D +E ++ +H ++I+ G +
Sbjct 513 EAFLKSENN-SGQKVAVKVLKTDINSSSDIEQCLKEAAYMKDFHHPNVIQLIGVSLHRRA 571
Query 972 KS----LQLVMEYVPLGSLRDYLPRHSIGLAQ-------LLLFAQQICEGMAYLHAQHYI 1020
+ +++ ++ G L +L +G L+ F I GM YL ++ I
Sbjct 572 QQRLPIPMVILPFMKHGDLHTFLLMSRLGDEPFTVSQQILIQFMLDIARGMEYLSNKNII 631
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARN +L+ + V + DFGL+K + G +YYR PV W A E L + +
Sbjct 632 HRDLAARNCMLNENMSVCVADFGLSKKIYSG-DYYRQGSVSKLPVKWIALESLADNVYTT 690
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVW+FGVT++E++T + + E L +GERL +P C
Sbjct 691 QSDVWAFGVTMWEIMTRGQ--------------TPYPGVENSEIYEYLIKGERLKQPPDC 736
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
P ++Y +M +CW RP+F++LI L+ + K
Sbjct 737 PADIYEIMHSCWSPVPKCRPSFQHLIDQLELLWAKLN 773
Score = 217 bits (552), Expect = 5e-57, Method: Composition-based stats.
Identities = 63/300 (21%), Positives = 118/300 (39%), Gaps = 47/300 (16%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+T LG+G +V E L+ E + GQ++ V + D +
Sbjct 497 LTLGRMLGKGEFGSVREAFLKSEN-------------------NSGQKVAVKVLKTDINS 537
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEYVEHGPLDVWLRRE 702
+ A+ M H ++ + GV + P +++ +++HG L +L
Sbjct 538 SSDIEQCLKEAAYMKDFHHPNVIQLIGVSLHRRAQQRLPIPMVILPFMKHGDLHTFLLMS 597
Query 703 R---GHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
R ++ ++++ +A + YL NKN++H ++ RN +L + + +
Sbjct 598 RLGDEPFTVSQQILIQFMLDIARGMEYLSNKNIIHRDLAARNCMLNE-------NMSVCV 650
Query 758 SDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
+D G+ S + + + W+A E L +T D W FG T+ EI G
Sbjct 651 ADFGLSKKIYSGDYYRQGSVSKLPVKWIALESLADNV--YTTQSDVWAFGVTMWEIMTRG 708
Query 812 EAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ P SE + + RL P + + C + P RPSF+ ++ L L
Sbjct 709 QTPYPGVENSEIYEYLIKGERLKQPPDCPADIYEIMHSCWSPVPKCRPSFQHLIDQLELL 768
>sp|P57097|MERTK_RAT Tyrosine-protein kinase Mer OS=Rattus norvegicus
OX=10116 GN=Mertk PE=2 SV=1
Length=994
Score = 261 bits (667), Expect = 3e-71, Method: Composition-based stats.
Identities = 90/283 (32%), Positives = 136/283 (48%), Gaps = 27/283 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG FG V DGT + VAVK +K D + + E ++ H ++I+
Sbjct 588 LGEGEFGSVMEGNLK-QEDGTSQKVAVKTMKLDNFSLREIEEFLSEAACMKDFNHPNVIR 646
Query 962 YKGCCED---QGEKSLQLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEGM 1011
G C + QG +++ ++ G L +L SI L LL F I +GM
Sbjct 647 LLGVCIELSSQGIPKPMVILPFMKYGDLHTFLLYSRIESVPKSIPLQTLLKFMVDIAQGM 706
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
YL +++++HRDLAARN +L +D V + DFGL+K + G +YYR PV W A E
Sbjct 707 EYLSSRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQGRIAKMPVKWIAIE 765
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
L + + SDVW+FGVT++E+ T + + + L G
Sbjct 766 SLADRVYTSKSDVWAFGVTMWEIATRG--------------MTPYPGVQNHEMYDYLLHG 811
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
RL +P+ C ++Y +M +CW + RPTF L L+ + E
Sbjct 812 HRLKQPEDCLDDLYEIMYSCWSADPLDRPTFSVLRLQLEKLSE 854
Score = 234 bits (596), Expect = 4e-62, Method: Composition-based stats.
Identities = 67/313 (21%), Positives = 119/313 (38%), Gaps = 50/313 (16%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
++L VD+ + LG+G +V EG L+ E G
Sbjct 570 NKLEDVVVDRNLLILGKVLGEGEFGSVMEGNLKQED---------------------GTS 608
Query 637 LRVVLKV--LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-----GPENIMVTEY 689
+V +K LD F A+ M +H ++ + GVC+ P+ +++ +
Sbjct 609 QKVAVKTMKLDNFSLREIEEFLSEAACMKDFNHPNVIRLLGVCIELSSQGIPKPMVILPF 668
Query 690 VEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+++G L +L R +P+ + +A + YL ++N +H ++ RN +L
Sbjct 669 MKYGDLHTFLLYSRIESVPKSIPLQTLLKFMVDIAQGMEYLSSRNFLHRDLAARNCML-- 726
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKW 798
+ ++D G+ S + + W+A E L ++ D W
Sbjct 727 -----RDDMTVCVADFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRV--YTSKSDVW 779
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
FG T+ EI G P E + HRL PE L + C + +P R
Sbjct 780 AFGVTMWEIATRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDDLYEIMYSCWSADPLDR 839
Query 857 PSFRTILRDLTRL 869
P+F + L +L
Sbjct 840 PTFSVLRLQLEKL 852
>sp|O54967|ACK1_MOUSE Activated CDC42 kinase 1 OS=Mus musculus
OX=10090 GN=Tnk2 PE=1 SV=2
Length=1055
Score = 261 bits (668), Expect = 5e-71, Method: Composition-based stats.
Identities = 107/272 (39%), Positives = 151/272 (56%), Gaps = 21/272 (8%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG V +D T VAVK LK D P+ + +E++ + +L H ++
Sbjct 131 KLGDGSFGVVRRGEWDAPAGKT-VSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNL 189
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQ 1017
I+ G +++V E PLGSL D L +H L L +A Q+ EGMAYL ++
Sbjct 190 IRLYGVVLTL---PMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMAYLESK 246
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+IHRDLAARN+LL LVKIGDFGL +A+P+ ++Y ++E P W APE LK
Sbjct 247 RFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRT 306
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F +ASD W FGVTL+E+ T+ IG+ Q+ L ++ + GERLPRP
Sbjct 307 FSHASDTWMFGVTLWEMFTYGQEP---------WIGLNGSQI----LHKIDKEGERLPRP 353
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ CP ++Y++M CW + RPTF L L
Sbjct 354 EDCPQDIYNVMVQCWAHKPEDRPTFVALRDFL 385
Score = 231 bits (590), Expect = 3e-61, Method: Composition-based stats.
Identities = 87/353 (25%), Positives = 137/353 (39%), Gaps = 54/353 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ +K++ L LG G+ V G G+ + V +K
Sbjct 121 IGEKDLRLLEKLGDGSFGVVRRGEWDAPA---------------------GKTVSVAVKC 159
Query 644 LDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
L P S + F + M + H +L ++GV + P MVTE G L LR
Sbjct 160 LKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTLPMK-MVTELAPLGSLLDRLR 218
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ +GH + A Q+A ++YLE+K +H ++ RN+LLA T +K+ D
Sbjct 219 KHQGHFLLGTLSRYAVQVAEGMAYLESKRFIHRDLAARNLLLA-------TRDLVKIGDF 271
Query 761 GVGLG-------ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ + +E R W APE L + S A D W FG TL E+ G+
Sbjct 272 GLMRALPQNDDHYVMQEHRKVPFAWCAPESLKT--RTFSHASDTWMFGVTLWEMFTYGQE 329
Query 814 PLQSRSPSEKEH-FYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P + S+ H + RLP P CPQ + + QC ++P RP+F + L Q
Sbjct 330 PWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQ 389
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923
P ++ + ++ G+ Y + N T
Sbjct 390 PTDMRALQDFEEPDKLHIQMNDVITVIE----------GRAENYWWRGQNTRT 432
>sp|P11273|ERBB_AVIEU Tyrosine-protein kinase transforming protein
erbB OS=Avian erythroblastosis virus (strain ts167) OX=103898
GN=V-ERBB PE=3 SV=1
Length=540
Score = 251 bits (640), Expect = 5e-71, Method: Composition-based stats.
Identities = 92/272 (34%), Positives = 136/272 (50%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + VA+K L+ P+ E ++ ++ + H+ +
Sbjct 138 LGFGAFGTVYKGLWIPEGEKVTIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRL 197
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C +QL+ + +P G L DY+ H IG LL + QI +GM YL +H +
Sbjct 198 LGICLTST---VQLITQLMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERHMV 254
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ + VKI DFGLAK + + Y E G P+ W A E + + +
Sbjct 255 HRDLAARNVLVKTPQHVKITDFGLAKQLGADEKEYHA-EGGKVPIKWMALESILHRIYTH 313
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + ++ +LE+GERLP+P C
Sbjct 314 QSDVWSYGVTVWELMTFGSK--------------PYDGIPASEISSVLEKGERLPQPPIC 359
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW ++A RP F LI +
Sbjct 360 TIDVYMIMVKCWMSDADSRPKFRELIAEFSKM 391
Score = 221 bits (564), Expect = 7e-61, Method: Composition-based stats.
Identities = 67/345 (19%), Positives = 136/345 (39%), Gaps = 39/345 (11%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P +Q + + E ++ LG G VY+G EG
Sbjct 113 TPSGEAPNQAHLRILKETEFKKVKVLGFGAFGTVYKGLWIPEGEKVT------------- 159
Query 630 GRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+ V +K L + + A +M+ V + H+ + G+C+ ++T+
Sbjct 160 -------IPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQ-LITQ 211
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ +G L ++R + ++ + + Q+A ++YLE +++VH ++ RN+L+
Sbjct 212 LMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERHMVHRDLAARNVLV------ 265
Query 749 EGTSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGA 802
T +K++D G+ LGA +E E I W+A E + + D W +G
Sbjct 266 -KTPQHVKITDFGLAKQLGADEKEYHAEGGKVPIKWMALESILHRI--YTHQSDVWSYGV 322
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860
T+ E+ G P SE ++ RLP+P + + +C + RP FR
Sbjct 323 TVWELMTFGSKPYDGIPASEISSVLEKGERLPQPPICTIDVYMIMVKCWMSDADSRPKFR 382
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
++ + +++ ++ + K Y + +
Sbjct 383 ELIAEFSKMARDPPRYLVIQGDERMHLPSPTDSKFYRTLMEEEDM 427
>sp|Q9SYS7|CRK39_ARATH Putative cysteine-rich receptor-like protein
kinase 39 OS=Arabidopsis thaliana OX=3702 GN=CRK39 PE=3
SV=1
Length=659
Score = 254 bits (648), Expect = 6e-71, Method: Composition-based stats.
Identities = 73/276 (26%), Positives = 116/276 (42%), Gaps = 20/276 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG+G FG V G+ VAVK L G +K E+ +L L H +++
Sbjct 357 NTLGQGGFGTVYKGTL-----LNGQEVAVKRLTKGSGQGDIE-FKNEVSLLTRLQHRNLV 410
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016
K G C + E+ LV E+VP SL ++ R + + I G+ YLH
Sbjct 411 KLLGFCNEGDEQ--ILVYEFVPNSSLDHFIFDDEKRSLLTWEMRYRIIEGIARGLLYLHE 468
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRDL A N+LLD + K+ DFG A+ + + APE L
Sbjct 469 DSQLKIIHRDLKASNILLDAEMNPKVADFGTARLFDSDETRAETKRIA-GTRGYMAPEYL 527
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ SDV+SFGV L E+++ ++ + E + + V E++
Sbjct 528 NHGQISAKSDVYSFGVMLLEMISGERNN----SFEGEGLAAFAWKRWVEGKPEIIIDPFL 583
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ +P ++ + C + + RPT ++I L
Sbjct 584 IEKPRNEIIKLIQIGLLCVQENPTKRPTMSSVIIWL 619
Score = 246 bits (627), Expect = 3e-68, Method: Composition-based stats.
Identities = 71/338 (21%), Positives = 116/338 (34%), Gaps = 60/338 (18%)
Query 554 QPGETSNLIIMRGARASPRTLNL---SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRV 610
+ E+ N I + A S L E + + LGQG VY+G L
Sbjct 315 RRKESYNKINVGSAEYSDSDGQFMLRFDLGMVLAATDEFSSENTLGQGGFGTVYKGTLLN 374
Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670
V +K L + F SL++++ H +L
Sbjct 375 GQ-------------------------EVAVKRLTKGSGQGDIEFKNEVSLLTRLQHRNL 409
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK 728
+ G C G E I+V E+V + LD ++ + + W + + + +A L YL
Sbjct 410 VKLLGFCNEGDEQILVYEFVPNSSLDHFIFDDEKRSLLTWEMRYRIIEGIARGLLYLHED 469
Query 729 ---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWL 779
++H ++ NILL K++D G S E R ++
Sbjct 470 SQLKIIHRDLKASNILLD-------AEMNPKVADFGTARLFDSDETRAETKRIAGTRGYM 522
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGE----------APLQSRSPSEKEHFYQR 829
APE L G +S D + FG LLE+ A R K
Sbjct 523 APEYLNHG--QISAKSDVYSFGVMLLEMISGERNNSFEGEGLAAFAWKRWVEGKPEIIID 580
Query 830 QHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ P +L + C+ PT+RP+ +++
Sbjct 581 PFLIEKPRNEIIKLIQIGLLCVQENPTKRPTMSSVIIW 618
>sp|Q93105|INSR_AEDAE Insulin-like receptor OS=Aedes aegypti OX=7159
GN=InR PE=2 SV=2
Length=1393
Score = 264 bits (674), Expect = 7e-71, Method: Composition-based stats.
Identities = 91/321 (28%), Positives = 152/321 (47%), Gaps = 31/321 (10%)
Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPTND 921
R +++ D + ++ ++ +LG+G FG V +
Sbjct 991 YRYMSKQIRMYPEVNPDYAGVQYKVDDWEVERNHIIQLEELGQGSFGMVYKGILTQLRGE 1050
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
+ A+K + + + + E +++ H+++ G QG+ +L ++ME +
Sbjct 1051 KCNQPCAIKTVNESATAREKDSFLLEASVMKQFNTHHVVRLLGVV-SQGDPTL-VIMELM 1108
Query 982 PLGSLRDYLPRHSIG-------------LAQLLLFAQQICEGMAYLHAQHYIHRDLAARN 1028
G L+ YL RH L Q++ A +I +GMAYL A+ ++HRDLAARN
Sbjct 1109 ANGDLKSYLRRHRPDYENGEDPSPQPPTLRQIIQMAIEIADGMAYLSAKKFVHRDLAARN 1168
Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
++ +D VKIGDFG+ + + E +YYR G PV W APE LK+ F +SDV+S+G
Sbjct 1169 CMVADDMTVKIGDFGMTRDIYE-TDYYRKGTKGFLPVRWMAPESLKDGIFSSSSDVFSYG 1227
Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148
V L+E+ T L +T ++ + G + RP+ CP +Y+LM
Sbjct 1228 VVLWEMAT--------------LASQPYQGLTNDQVLRYVIDGGVMERPENCPDNLYNLM 1273
Query 1149 KNCWETEASFRPTFENLIPIL 1169
+ CW+ + RPTF +I L
Sbjct 1274 RRCWQHRPTARPTFMEIISEL 1294
Score = 244 bits (622), Expect = 1e-64, Method: Composition-based stats.
Identities = 68/305 (22%), Positives = 118/305 (39%), Gaps = 48/305 (16%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
++ V++ I QL LGQG+ VY+G L R
Sbjct 1014 KVDDWEVERNHIIQLEELGQGSFGMVYKGIL-------------------TQLRGEKCNQ 1054
Query 638 RVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+K ++ S F AS+M Q + H+ + GV +G +++ E + +G L
Sbjct 1055 PCAIKTVNESATAREKDSFLLEASVMKQFNTHHVVRLLGVVSQGDPTLVIMELMANGDLK 1114
Query 697 VWLRRERG-----------HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
+LRR R + + +A ++A ++YL K VH ++ RN ++A
Sbjct 1115 SYLRRHRPDYENGEDPSPQPPTLRQIIQMAIEIADGMAYLSAKKFVHRDLAARNCMVA-- 1172
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWG 799
+K+ D G+ + + + W+APE L G S++ D +
Sbjct 1173 -----DDMTVKIGDFGMTRDIYETDYYRKGTKGFLPVRWMAPESLKDGI--FSSSSDVFS 1225
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857
+G L E+ P Q + + + + PE L L +C + PT RP
Sbjct 1226 YGVVLWEMATLASQPYQGLTNDQVLRYVIDGGVMERPENCPDNLYNLMRRCWQHRPTARP 1285
Query 858 SFRTI 862
+F I
Sbjct 1286 TFMEI 1290
>sp|O64771|Y1148_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61480 OS=Arabidopsis thaliana OX=3702
GN=At1g61480 PE=2 SV=2
Length=809
Score = 257 bits (656), Expect = 7e-71, Method: Composition-based stats.
Identities = 79/307 (26%), Positives = 125/307 (41%), Gaps = 17/307 (6%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
+ LG+G FG V G+ +AVK L + G Q +
Sbjct 483 FFEMNTIQTATDNFSLSNKLGQGGFGSVYKGKLQ-----DGKEIAVKRLSSSSG-QGKEE 536
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ 999
+ EI ++ L H+++++ GCC + E+ LV E++ SL +L R I +
Sbjct 537 FMNEIVLISKLQHKNLVRILGCCIEGEER--LLVYEFLLNKSLDTFLFDSRKRLEIDWPK 594
Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
+ I G+ YLH IHRDL N+LLD KI DFGLA+ + +G EY
Sbjct 595 RFNIIEGIARGLHYLHRDSCLRVIHRDLKVSNILLDEKMNPKISDFGLAR-MYQGTEYQD 653
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIA 1115
+ + APE F SD++SFGV L E++T S S + L+ A
Sbjct 654 NTRRVAGTLGYMAPEYAWTGMFSEKSDIYSFGVILLEIITGEKISRFSYGRQGKTLLAYA 713
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+LL++ + C + + + RP L+ +L T +
Sbjct 714 WESWCESGGIDLLDKDVADSCHPLEVERCVQIGLLCVQHQPADRPNTMELLSMLTTTSDL 773
Query 1176 YQGQAPS 1182
+ P+
Sbjct 774 TSPKQPT 780
Score = 235 bits (599), Expect = 3e-63, Method: Composition-based stats.
Identities = 54/247 (22%), Positives = 95/247 (38%), Gaps = 45/247 (18%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L +++ + + + LGQG +VY+G+L+
Sbjct 481 LKFFEMNTIQTATDNFSLSNKLGQGGFGSVYKGKLQDGK--------------------- 519
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ +K L S F L+S++ H +L + G C+ G E ++V E++ +
Sbjct 520 ----EIAVKRLSSSSGQGKEEFMNEIVLISKLQHKNLVRILGCCIEGEERLLVYEFLLNK 575
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748
LD +L R + + W + + + +A L YL ++H ++ NILL
Sbjct 576 SLDTFLFDSRKRLEIDWPKRFNIIEGIARGLHYLHRDSCLRVIHRDLKVSNILLDEK--- 632
Query 749 EGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGA 802
K+SD G+ E + + ++APE G S D + FG
Sbjct 633 ----MNPKISDFGLARMYQGTEYQDNTRRVAGTLGYMAPEYAWTGM--FSEKSDIYSFGV 686
Query 803 TLLEICF 809
LLEI
Sbjct 687 ILLEIIT 693
>sp|Q04912|RON_HUMAN Macrophage-stimulating protein receptor OS=Homo
sapiens OX=9606 GN=MST1R PE=1 SV=3
Length=1400
Score = 263 bits (673), Expect = 9e-71, Method: Composition-based stats.
Identities = 93/303 (31%), Positives = 142/303 (47%), Gaps = 27/303 (9%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCY--DPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
+ R +G+GHFG V Y N A+K+L Q + +E
Sbjct 1076 PHERVVTHSDRVIGKGHFGVVYHGEYIDQAQNRI---QCAIKSLSRITEMQQVEAFLREG 1132
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQ 1006
++R L H +++ G E +++ Y+ G L ++ P+ + + L+ F Q
Sbjct 1133 LLMRGLNHPNVLALIGIML-PPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQ 1191
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPV 1065
+ GM YL Q ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV
Sbjct 1192 VARGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPV 1251
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
W A E L+ Y+F SDVWSFGV L+ELLT + LT
Sbjct 1252 KWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAP--------------PYRHIDPFDLT 1297
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG----QAP 1181
L +G RLP+P+ CP +Y +M+ CWE + + RPTF L+ ++ + G Q P
Sbjct 1298 HFLAQGRRLPQPEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLP 1357
Query 1182 SVF 1184
+ +
Sbjct 1358 ATY 1360
Score = 229 bits (583), Expect = 9e-60, Method: Composition-based stats.
Identities = 68/318 (21%), Positives = 121/318 (38%), Gaps = 44/318 (14%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDI 651
+G+G VY G + ++ +K L +
Sbjct 1086 RVIGKGHFGVVYHGEYIDQAQNR---------------------IQCAIKSLSRITEMQQ 1124
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCV--RGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
AF LM ++H ++ + G+ + G +++ Y+ HG L ++R + + +
Sbjct 1125 VEAFLREGLLMRGLNHPNVLALIGIMLPPEGLPHVL-LPYMCHGDLLQFIRSPQRNPTVK 1183
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+ Q+A + YL + VH ++ RN +L S +K++D G+ L R
Sbjct 1184 DLISFGLQVARGMEYLAEQKFVHRDLAARNCMLDE-------SFTVKVADFGLARDILDR 1236
Query 770 EERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
E + W+A E L +T D W FG L E+ G P + P
Sbjct 1237 EYYSVQQHRHARLPVKWMALESLQT--YRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPF 1294
Query 822 EKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
+ HF + RLP+P CP L + QC +P RP+FR ++ ++ ++ L D
Sbjct 1295 DLTHFLAQGRRLPQPEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYV 1354
Query 880 VNPDSPASDPTVFHKRYL 897
P + +
Sbjct 1355 QLPATYMNLGPSTSHEMN 1372
>sp|Q9FG33|LRKS5_ARATH Probable L-type lectin-domain containing
receptor kinase S.5 OS=Arabidopsis thaliana OX=3702 GN=LECRKS5
PE=2 SV=1
Length=652
Score = 253 bits (646), Expect = 9e-71, Method: Composition-based stats.
Identities = 66/283 (23%), Positives = 120/283 (42%), Gaps = 22/283 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG+G FG V + + +AVK + ++ Q + + EI + L H +++
Sbjct 334 NKLGQGGFGMVFKGKWQGRD------IAVKRV-SEKSHQGKQEFIAEITTIGNLNHRNLV 386
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLH 1015
K G C ++ E LV EY+P GSL YL R ++ + + + YLH
Sbjct 387 KLLGWCYERKE--YLLVYEYMPNGSLDKYLFLEDKSRSNLTWETRKNIITGLSQALEYLH 444
Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+ +HRD+ A NV+LD+D K+GDFGLA+ + + + ++ + APE
Sbjct 445 NGCEKRILHRDIKASNVMLDSDFNAKLGDFGLARMIQQSEMTHHSTKEIAGTPGYMAPET 504
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE-----LIGIAQGQMTVLRLTEL 1127
+ +DV++FGV + E+++ S ++ +T+
Sbjct 505 FLNGRATVETDVYAFGVLMLEVVSGKKPSYVLVKDNQNNYNNSIVNWLWELYRNGTITDA 564
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ G + V L C + RP+ + ++ +L
Sbjct 565 ADPGMGNLFDKEEMKSVLLLGLACCHPNPNQRPSMKTVLKVLT 607
Score = 227 bits (579), Expect = 7e-62, Method: Composition-based stats.
Identities = 65/329 (20%), Positives = 120/329 (36%), Gaps = 74/329 (22%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
A+P+ L +L + + LGQG V++G+
Sbjct 313 ANPQKFKLREL---KRATGNFGAENKLGQGGFGMVFKGKW-------------------- 349
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
Q + +K + H F + + ++H +L + G C E ++V E
Sbjct 350 ------QGRDIAVKRVSEKSHQGKQEFIAEITTIGNLNHRNLVKLLGWCYERKEYLLVYE 403
Query 689 YVEHGPLDVWLR---RERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILL 742
Y+ +G LD +L + R ++ + + L+ AL YL N K ++H ++ N++L
Sbjct 404 YMPNGSLDKYLFLEDKSRSNLTWETRKNIITGLSQALEYLHNGCEKRILHRDIKASNVML 463
Query 743 ARLGLAEGTSPFIKLSDPGVGL-------GALSREERVERIPWLAPECLPGGANSLSTAM 795
+ KL D G+ S +E ++APE G ++ T
Sbjct 464 D-------SDFNAKLGDFGLARMIQQSEMTHHSTKEIAGTPGYMAPETFLNGRATVET-- 514
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFY----------QRQHRLPEPSCPQLATLT 845
D + FG +LE+ G+ P + ++ R + + + P + L
Sbjct 515 DVYAFGVLMLEVVS-GKKPSYVLVKDNQNNYNNSIVNWLWELYRNGTITDAADPGMGNLF 573
Query 846 SQ------------CLTYEPTQRPSFRTI 862
+ C P QRPS +T+
Sbjct 574 DKEEMKSVLLLGLACCHPNPNQRPSMKTV 602
>sp|Q5U2X5|ACK1_RAT Activated CDC42 kinase 1 OS=Rattus norvegicus
OX=10116 GN=Tnk2 PE=2 SV=1
Length=1040
Score = 260 bits (665), Expect = 9e-71, Method: Composition-based stats.
Identities = 106/272 (39%), Positives = 149/272 (55%), Gaps = 21/272 (8%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG V +D T VAVK LK D P+ + +E++ + +L H ++
Sbjct 131 KLGDGSFGVVRRGEWDAPAGKT-VSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNL 189
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQ 1017
I+ G +++V E PLGSL D L +H L L +A Q+ EGM YL ++
Sbjct 190 IRLYGVVLTP---PMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESK 246
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+IHRDLAARN+LL LVKIGDFGL +A+P+ +Y ++E P W APE LK
Sbjct 247 RFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDGHYVMQEHRKVPFAWCAPESLKTRT 306
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F +ASD W FGVTL+E+ T+ IG+ Q+ L ++ + GERLPRP
Sbjct 307 FSHASDTWMFGVTLWEMFTYGQEP---------WIGLNGSQI----LHKIDKEGERLPRP 353
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ CP ++Y++M CW + RPTF L L
Sbjct 354 EDCPQDIYNVMVQCWAHKPEDRPTFVALRDFL 385
Score = 233 bits (594), Expect = 1e-61, Method: Composition-based stats.
Identities = 87/353 (25%), Positives = 136/353 (39%), Gaps = 54/353 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ +K++ L LG G+ V G G+ + V +K
Sbjct 121 IGEKDLRLLEKLGDGSFGVVRRGEWDAPA---------------------GKTVSVAVKC 159
Query 644 LDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
L P S + F + M + H +L ++GV + P MVTE G L LR
Sbjct 160 LKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLT-PPMKMVTELAPLGSLLDRLR 218
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ +GH + A Q+A + YLE+K +H ++ RN+LLA T +K+ D
Sbjct 219 KHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLA-------TRDLVKIGDF 271
Query 761 GVGLG-------ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ + +E R W APE L + S A D W FG TL E+ G+
Sbjct 272 GLMRALPQNDGHYVMQEHRKVPFAWCAPESLKT--RTFSHASDTWMFGVTLWEMFTYGQE 329
Query 814 PLQSRSPSEKEH-FYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P + S+ H + RLP P CPQ + + QC ++P RP+F + L Q
Sbjct 330 PWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQ 389
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923
P ++ + ++ G+ Y + N T
Sbjct 390 PTDMRALQDFEEPDKLHIQMNDVITVIE----------GRAENYWWRGQNTRT 432
>sp|Q8RWW0|ALE2_ARATH Receptor-like serine/threonine-protein kinase
ALE2 OS=Arabidopsis thaliana OX=3702 GN=ALE2 PE=1 SV=1
Length=744
Score = 255 bits (652), Expect = 1e-70, Method: Composition-based stats.
Identities = 89/348 (26%), Positives = 135/348 (39%), Gaps = 22/348 (6%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
P F + R + ++ + R LGEG FG
Sbjct 302 NKRPGAGSMFSSSARSSGSDSLMSSMATCALSVKTFTLSELEKATDRFSAKRVLGEGGFG 361
Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
+V + G VAVK L D + R + E+++L L+H +++K G C +
Sbjct 362 RVYQG-----SMEDGTEVAVKLLTRDNQNRDRE-FIAEVEMLSRLHHRNLVKLIGICIEG 415
Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAA 1026
+ L+ E V GS+ +L ++ L A G+AYLH IHRD A
Sbjct 416 RTR--CLIYELVHNGSVESHLHEGTLDWDARLKIALGAARGLAYLHEDSNPRVIHRDFKA 473
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
NVLL++D K+ DFGLA+ EG ++ R + APE SDV+S
Sbjct 474 SNVLLEDDFTPKVSDFGLAREATEGSQHISTR--VMGTFGYVAPEYAMTGHLLVKSDVYS 531
Query 1087 FGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLR-LTELLERGERLPRPDKCPCEV 1144
+GV L ELLT S P+ L+ A+ + L +L++ +V
Sbjct 532 YGVVLLELLTGRRPVDMSQPSGEENLVTWARPLLANREGLEQLVDPALAGTYNFDDMAKV 591
Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHE-------KYQGQAPSVFS 1185
+ C E S RP ++ LK ++ Y Q S
Sbjct 592 AAIASMCVHQEVSHRPFMGEVVQALKLIYNDADETCGDYCSQKDSSVP 639
Score = 223 bits (569), Expect = 6e-60, Method: Composition-based stats.
Identities = 63/338 (19%), Positives = 116/338 (34%), Gaps = 67/338 (20%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
S +T LS+L + LG+G VY+G +
Sbjct 333 SVKTFTLSELEK---ATDRFSAKRVLGEGGFGRVYQGSMEDG------------------ 371
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
V +K+L + + F ++S++ H +L + G+C+ G ++ E
Sbjct 372 -------TEVAVKLLTRDNQNRDREFIAEVEMLSRLHHRNLVKLIGICIEGRTRCLIYEL 424
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLG 746
V +G ++ L G + ++ +A A L+YL ++H + N+LL
Sbjct 425 VHNGSVESHLH--EGTLDWDARLKIALGAARGLAYLHEDSNPRVIHRDFKASNVLL---- 478
Query 747 LAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFG 801
K+SD G+ A + + ++APE G L D + +G
Sbjct 479 ---EDDFTPKVSDFGLAREATEGSQHISTRVMGTFGYVAPEYAMTG--HLLVKSDVYSYG 533
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-------------------PEPSCPQLA 842
LLE+ G P+ PS +E+ L ++A
Sbjct 534 VVLLELL-TGRRPVDMSQPSGEENLVTWARPLLANREGLEQLVDPALAGTYNFDDMAKVA 592
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880
+ S C+ E + RP +++ L +
Sbjct 593 AIASMCVHQEVSHRPFMGEVVQALKLIYNDADETCGDY 630
>sp|P08922|ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS
OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3
Length=2347
Score = 264 bits (675), Expect = 1e-70, Method: Composition-based stats.
Identities = 96/287 (33%), Positives = 139/287 (48%), Gaps = 32/287 (11%)
Query 903 LGEGHFGKVSLYC-YDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG G FG+V D G+GE VAVK LK Q + + +E ++ H +I+
Sbjct 1951 LGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNIL 2010
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI--------GLAQLLLFAQQICEGMA 1012
K G C + +++E + G L YL + + L L+ I +G
Sbjct 2011 KQLGVCLLNEPQ--YIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCV 2068
Query 1013 YLHAQHYIHRDLAARNVLL-----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
YL H+IHRDLAARN L+ + R+VKIGDFGLA+ + + ++YYR R +G PV W
Sbjct 2069 YLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYK-NDYYRKRGEGLLPVRW 2127
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE L + F SDVWSFG+ ++E+LT L + L +
Sbjct 2128 MAPESLMDGIFTTQSDVWSFGILIWEILT--------------LGHQPYPAHSNLDVLNY 2173
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
++ G RL P CP ++++LM CW E RPTF + L+
Sbjct 2174 VQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRN 2220
Score = 250 bits (638), Expect = 3e-66, Method: Composition-based stats.
Identities = 78/317 (25%), Positives = 129/317 (41%), Gaps = 37/317 (12%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
++++T LG G VYEG D L G E++V +K L
Sbjct 1941 PREKLTLRLLLGSGAFGEVYEGT---------------AVDILGVGSG---EIKVAVKTL 1982
Query 645 DPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
D F + A LMS+ +H ++ GVC+ ++ E +E G L +LR+ R
Sbjct 1983 KKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKAR 2042
Query 704 ------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ + + + ++ YLE + +H ++ RN L++ + +K+
Sbjct 2043 MATFYGPLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVK--DYTSPRIVKI 2100
Query 758 SDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
D G+ + +R + W+APE L G +T D W FG + EI G
Sbjct 2101 GDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGI--FTTQSDVWSFGILIWEILTLG 2158
Query 812 EAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
P + S + ++ Q RL P +CP L L +QC EP QRP+F I L
Sbjct 2159 HQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLF 2218
Query 870 QPHNLADVLTVNPDSPA 886
+ L + ++
Sbjct 2219 RNFFLNSIYKSRDEANN 2235
>sp|Q9FM85|PBL16_ARATH Probable serine/threonine-protein kinase
PBL16 OS=Arabidopsis thaliana OX=3702 GN=PBL16 PE=1 SV=1
Length=408
Score = 245 bits (626), Expect = 1e-70, Method: Composition-based stats.
Identities = 82/290 (28%), Positives = 125/290 (43%), Gaps = 16/290 (6%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-----VAVKALKADCGPQHRSGWKQEIDI 950
++ R LG G FG V + G E+ VAVK D Q W E+
Sbjct 75 NFRQDRVLGGGGFGSVYKGFIK-EDLGDQEVPEPLPVAVKVHDGDNSFQGHREWLAEVIF 133
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQI 1007
L L H +++K G C + + L+ EY+ GS+ + L + A + A
Sbjct 134 LGQLSHPNLVKLIGYCCEDNHR--VLIYEYMARGSVENNLFSRVLLPLSWAIRMKIAFGA 191
Query 1008 CEGMAYLHA--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
+G+A+LH + I+RD N+LLD D K+ DFGLAK P G + + V
Sbjct 192 AKGLAFLHEAKKPVIYRDFKTSNILLDMDYNAKLSDFGLAKDGPVGDKSH-VSTRIMGTY 250
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQM-TVLR 1123
+ APE + SDV+SFGV L ELLT S +S PT+ LI A + +
Sbjct 251 GYAAPEYIMTGHLTPGSDVYSFGVVLLELLTGRKSLDKSRPTREQNLIDWALPLLKEKKK 310
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ +++ P K + L +C RP +++ L+ +
Sbjct 311 VLNIVDPKMNCEYPVKAVQKAAMLAYHCLNRNPKARPLMRDIVDSLEPLQ 360
Score = 220 bits (560), Expect = 1e-61, Method: Composition-based stats.
Identities = 74/345 (21%), Positives = 128/345 (37%), Gaps = 56/345 (16%)
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P + +R A+ + + + Q LG G +VY+G ++ +
Sbjct 43 PSNPKEVEDLRRDSAANPLIAFTYEELKNI-TSNFRQDRVLGGGGFGSVYKGFIKED--- 98
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFV 673
+ D++ P L V +KV D + + + Q+SH +L +
Sbjct 99 ------LGDQEVPEP-------LPVAVKVHDGDNSFQGHREWLAEVIFLGQLSHPNLVKL 145
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN--KN 729
G C +++ EY+ G ++ L R +P++W +M +A A L++L K
Sbjct 146 IGYCCEDNHRVLIYEYMARGSVENNLF-SRVLLPLSWAIRMKIAFGAAKGLAFLHEAKKP 204
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPEC 783
+++ + NILL KLSD G+ ++ + + APE
Sbjct 205 VIYRDFKTSNILLD-------MDYNAKLSDFGLAKDGPVGDKSHVSTRIMGTYGYAAPEY 257
Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL---------- 833
+ G L+ D + FG LLE+ ++ +SR E+ L
Sbjct 258 IMTG--HLTPGSDVYSFGVVLLELLTGRKSLDKSRPTREQNLIDWALPLLKEKKKVLNIV 315
Query 834 -PEPSCPQ-------LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P+ +C A L CL P RP R I+ L LQ
Sbjct 316 DPKMNCEYPVKAVQKAAMLAYHCLNRNPKARPLMRDIVDSLEPLQ 360
>sp|Q75JK0|ZAK1_DICDI Dual specificity protein kinase zakA OS=Dictyostelium
discoideum OX=44689 GN=zakA PE=1 SV=1
Length=781
Score = 256 bits (654), Expect = 1e-70, Method: Composition-based stats.
Identities = 92/469 (20%), Positives = 160/469 (34%), Gaps = 92/469 (20%)
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832
+ ++APE + D W G T++E+ S+K +
Sbjct 235 IGTFNYMAPEV--KRNYRATRKSDVWSLGCTIIEMA--------GGDLSQKLN---GIPI 281
Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH-------------------- 872
+P+ L + CL +P +R +L +
Sbjct 282 IPDHLSDTLKDFLNHCLVIDPKKRSYMEELLSHKLIVHIIGPNKSKNYGVEPKFKDDDDF 341
Query 873 -------------NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919
+ P + + K + G G+FG V + T
Sbjct 342 EEIENEKDNYLSSRFPAKFAPQYEKPKWEIEFEELEFDKDDSEGGAGNFGDVKKGLLNET 401
Query 920 NDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGCCEDQGEK--SLQ 975
VA+K +K + E+ IL L H +I+++ C GEK +
Sbjct 402 ------EVAIKFVKKAHCEAITVCDTFYHEVLILSNLRHPNIVQFMAACIKYGEKETNHC 455
Query 976 LVMEYVPLGSLRDYLPRHSIGLAQ----LLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031
+V E++ G+L +L + L + I +G+ YLH QH IHRDL + NVLL
Sbjct 456 IVSEWMSGGNLTQFLMNNHKVLENNPHLRVKLLTDIAKGILYLHKQHIIHRDLTSNNVLL 515
Query 1032 D-------------NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
D N+ K+ DFGL+ E + + + APE L
Sbjct 516 DFKREILPNQLYGSNEFTAKVCDFGLSSNQSESKKL------RGGSIHYMAPENLNGSPI 569
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SD++SFG+ ++++ ++ + + ++ R P
Sbjct 570 NEKSDIYSFGLLVWQMFSYAPP------------NTIYSPKEMASMVSDPKQNYRPQIPF 617
Query 1139 KCPCEVYHLMKNCWETEASFRP-TFENLIPILKTVHEKYQGQAPSVFSV 1186
P + L+ CW+ RP F +I LK + Y + +V +
Sbjct 618 NVPLKFKELITQCWDRNPLNRPKDFSIIIEKLKEIGLTYNRSSSNVSPI 666
Score = 199 bits (507), Expect = 1e-51, Method: Composition-based stats.
Identities = 55/305 (18%), Positives = 111/305 (36%), Gaps = 53/305 (17%)
Query 582 HRVDQKEITQLS---HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
++ +E+ G G +V +G L E
Sbjct 369 WEIEFEELEFDKDDSEGGAGNFGDVKKGLL--------------------------NETE 402
Query 639 VVLKVLDPSHHDIA---LAFYETASLMSQVSHTHLAFVHGVCVRGPE----NIMVTEYVE 691
V +K + +H + FY ++S + H ++ C++ E + +V+E++
Sbjct 403 VAIKFVKKAHCEAITVCDTFYHEVLILSNLRHPNIVQFMAACIKYGEKETNHCIVSEWMS 462
Query 692 HGPLDVWLRRERGHVPMA--WKMVVAQQLASALSYLENKNLVHGNVCGRNILLA------ 743
G L +L + ++ + +A + YL ++++H ++ N+LL
Sbjct 463 GGNLTQFLMNNHKVLENNPHLRVKLLTDIAKGILYLHKQHIIHRDLTSNNVLLDFKREIL 522
Query 744 RLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
L K+ D G+ + S++ R I ++APE L G + ++ D + FG
Sbjct 523 PNQLYGSNEFTAKVCDFGLSSNQSESKKLRGGSIHYMAPENLNG--SPINEKSDIYSFGL 580
Query 803 TLLEICFDGEAPLQSRSPSEKEHF-----YQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857
+ ++ P SP E + ++P + L +QC P RP
Sbjct 581 LVWQMFSYA-PPNTIYSPKEMASMVSDPKQNYRPQIPFNVPLKFKELITQCWDRNPLNRP 639
Query 858 SFRTI 862
+I
Sbjct 640 KDFSI 644
Score = 114 bits (286), Expect = 1e-24, Method: Composition-based stats.
Identities = 37/164 (23%), Positives = 75/164 (46%), Gaps = 13/164 (8%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM--VAVKALKADCGPQHRSGWKQ 946
+K ++I +GEG +G+V ++ VA+K + D +
Sbjct 1 MHYHNKDDWEEISFIGEGQYGRVIKCRKKNGFILNEQVDYVAIKIISKDKFK------RN 54
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLF 1003
E DIL + +I +Y + + + + MEY+ +L + L + ++++
Sbjct 55 ETDILEKIRLFNIPRYY--SHAEDDNFIYIYMEYIEGENLANILKTKKQGRFKESRIISM 112
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
+ E +++LH H IHRD+ N++LD ++ +K+ DFG +
Sbjct 113 IADLVETLSFLHKHHVIHRDIKTANLVLDKNKNLKLIDFGASTI 156
Score = 95.5 bits (236), Expect = 1e-18, Method: Composition-based stats.
Identities = 25/184 (14%), Positives = 66/184 (36%), Gaps = 31/184 (17%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
H ++ + ++S +G+G V + R + + + V +
Sbjct 2 HYHNKDDWEEISFIGEGQYGRVIKCRKKNGFILNEQVDY------------------VAI 43
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR- 700
K++ ++ ++ ++ + + EY+E L L+
Sbjct 44 KIISKDKFK-----RNETDILEKIRLFNIPRYYSHAEDDNFIYIYMEYIEGENLANILKT 98
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+++G + + + L LS+L +++H ++ N++L + + +KL D
Sbjct 99 KKQGRFKESRIISMIADLVETLSFLHKHHVIHRDIKTANLVLDK-------NKNLKLIDF 151
Query 761 GVGL 764
G
Sbjct 152 GAST 155
Score = 69.3 bits (168), Expect = 2e-10, Method: Composition-based stats.
Identities = 27/125 (22%), Positives = 42/125 (34%), Gaps = 29/125 (23%)
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
G++ + E +Y + + APE + Y+ SDVWS G T+ E+ D SQ
Sbjct 218 GISTYLNE--QYKQSSFAIIGTFNYMAPEVKRNYRATRKSDVWSLGCTIIEMA-GGDLSQ 274
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
L GI PD + + +C + R
Sbjct 275 K-------LNGI-------------------PIIPDHLSDTLKDFLNHCLVIDPKKRSYM 308
Query 1163 ENLIP 1167
E L+
Sbjct 309 EELLS 313
>sp|Q12866|MERTK_HUMAN Tyrosine-protein kinase Mer OS=Homo sapiens
OX=9606 GN=MERTK PE=1 SV=2
Length=999
Score = 260 bits (664), Expect = 1e-70, Method: Composition-based stats.
Identities = 93/284 (33%), Positives = 136/284 (48%), Gaps = 29/284 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ-HRSGWKQEIDILRTLYHEHIIK 961
LGEG FG V DGT VAVK +K D Q + E ++ H ++I+
Sbjct 593 LGEGEFGSVMEGNLK-QEDGTSLKVAVKTMKLDNSSQREIEEFLSEAACMKDFSHPNVIR 651
Query 962 YKGCCEDQGEKSL---QLVMEYVPLGSLRDYL--------PRHSIGLAQLLLFAQQICEG 1010
G C + + + +++ ++ G L YL P+H I L LL F I G
Sbjct 652 LLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKH-IPLQTLLKFMVDIALG 710
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
M YL ++++HRDLAARN +L +D V + DFGL+K + G +YYR PV W A
Sbjct 711 MEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQGRIAKMPVKWIAI 769
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E L + + SDVW+FGVT++E+ T + + + L
Sbjct 770 ESLADRVYTSKSDVWAFGVTMWEIATRG--------------MTPYPGVQNHEMYDYLLH 815
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
G RL +P+ C E+Y +M +CW T+ RPTF L L+ + E
Sbjct 816 GHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLE 859
Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats.
Identities = 71/313 (23%), Positives = 122/313 (39%), Gaps = 50/313 (16%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
++L +D+ + LG+G +V EG L+ E G
Sbjct 575 NKLEDVVIDRNLLILGKILGEGEFGSVMEGNLKQED---------------------GTS 613
Query 637 LRVVLKV--LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-----GPENIMVTEY 689
L+V +K LD S F A+ M SH ++ + GVC+ P+ +++ +
Sbjct 614 LKVAVKTMKLDNSSQREIEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPF 673
Query 690 VEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+++G L +L R H+P+ + +A + YL N+N +H ++ RN +L
Sbjct 674 MKYGDLHTYLLYSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCML-- 731
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKW 798
+ ++D G+ S + + W+A E L ++ D W
Sbjct 732 -----RDDMTVCVADFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRV--YTSKSDVW 784
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
FG T+ EI G P E + HRL PE +L + C +P R
Sbjct 785 AFGVTMWEIATRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDR 844
Query 857 PSFRTILRDLTRL 869
P+F + L +L
Sbjct 845 PTFSVLRLQLEKL 857
>sp|Q54Y55|SHKC_DICDI Dual specificity protein kinase shkC OS=Dictyostelium
discoideum OX=44689 GN=shkC PE=3 SV=1
Length=506
Score = 249 bits (635), Expect = 1e-70, Method: Composition-based stats.
Identities = 80/277 (29%), Positives = 131/277 (47%), Gaps = 31/277 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FGKV + VAVK L K + S +++E+ ++ +YH +I
Sbjct 30 IGTGSFGKVYKG------RCRQKAVAVKLLHKQNFDAATLSAFRKEVHLMSKIYHPNICL 83
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQH- 1018
+ G C G +V E VP G+L L I L + A+ G+ +LH +
Sbjct 84 FMGACTIPG--RCVIVTELVPKGNLETLLHDQKIQLPLYLRMRMARDAALGINWLHESNP 141
Query 1019 -YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
++HRD+ + N+L+D + VKI DFGL+ A+ + H+ + + + APE + +
Sbjct 142 VFVHRDIKSSNLLVDENMRVKICDFGLS-ALKQKHKMLKDQSSAKGTPLYMAPEVMMFKE 200
Query 1078 FYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
F +SDV+SFG+ L+E+LT + KF E + + ER P
Sbjct 201 FNESSDVYSFGIVLWEILTRKEPFSHHRELEKFREAVCVKH---------------ERPP 245
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P+ C + L++ CW+ E RP+F+ +I L V
Sbjct 246 IPNDCLDSLRRLIEKCWDKEPISRPSFKEIISALDHV 282
Score = 233 bits (595), Expect = 3e-65, Method: Composition-based stats.
Identities = 66/301 (22%), Positives = 114/301 (38%), Gaps = 48/301 (16%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ +EI +G G+ VY+GR R + V +
Sbjct 17 PEIRPEEINFEELIGTGSFGKVYKGRCR--------------------------QKAVAV 50
Query 642 KVLDPSHHDIAL--AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
K+L + D A AF + LMS++ H ++ G C ++VTE V G L+ L
Sbjct 51 KLLHKQNFDAATLSAFRKEVHLMSKIYHPNICLFMGACTIPGRCVIVTELVPKGNLETLL 110
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKL 757
++ +P+ +M +A+ A +++L N VH ++ N+L+ + +K+
Sbjct 111 HDQKIQLPLYLRMRMARDAALGINWLHESNPVFVHRDIKSSNLLVDE-------NMRVKI 163
Query 758 SDPGVG------LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
D G+ + ++APE + + + D + FG L EI
Sbjct 164 CDFGLSALKQKHKMLKDQSSAKGTPLYMAPEVMM--FKEFNESSDVYSFGIVLWEILTRK 221
Query 812 EAPLQSRSPS---EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
E R E + +P L L +C EP RPSF+ I+ L
Sbjct 222 EPFSHHRELEKFREAVCVKHERPPIPNDCLDSLRRLIEKCWDKEPISRPSFKEIISALDH 281
Query 869 L 869
+
Sbjct 282 V 282
>sp|Q9SJG2|Y2296_ARATH Probable receptor-like protein kinase At2g42960
OS=Arabidopsis thaliana OX=3702 GN=At2g42960 PE=3 SV=1
Length=494
Score = 248 bits (633), Expect = 1e-70, Method: Composition-based stats.
Identities = 69/278 (25%), Positives = 117/278 (42%), Gaps = 19/278 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG +G V G VAVK L + G Q ++ E++ + + H+++++
Sbjct 189 LGEGGYGVVYRG-----KLVNGTEVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRL 242
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMAYLHAQ 1017
G C + + LV EYV G+L +L ++ + + +AYLH
Sbjct 243 LGYCIEGVHR--MLVYEYVNSGNLEQWLHGAMRQHGNLTWEARMKIITGTAQALAYLHEA 300
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+HRD+ A N+L+D++ K+ DFGLAK + G + R + APE
Sbjct 301 IEPKVVHRDIKASNILIDDEFNAKLSDFGLAKLLDSGESHITTR--VMGTFGYVAPEYAN 358
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQMTVLRLTELLERGER 1133
SD++SFGV L E +T D P + L+ + + R E+++
Sbjct 359 TGLLNEKSDIYSFGVLLLEAITGRDPVDYGRPANEVNLVEWLKMMVGTRRAEEVVDPRLE 418
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ C + EA RP + +L++
Sbjct 419 PRPSKSALKRALLVSLRCVDPEAEKRPRMSQVARMLES 456
Score = 218 bits (555), Expect = 4e-60, Method: Composition-based stats.
Identities = 69/335 (21%), Positives = 111/335 (33%), Gaps = 62/335 (19%)
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
+ L + ++ LG+G VY G+L
Sbjct 169 HWFTLRDLELATNRFAPVNVLGEGGYGVVYRGKLVNG----------------------- 205
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
V +K L + F + V H +L + G C+ G ++V EYV G
Sbjct 206 --TEVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCIEGVHRMLVYEYVNSGN 263
Query 695 LDVWLR---RERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLA 748
L+ WL R+ G++ +M + A AL+YL +VH ++ NIL+
Sbjct 264 LEQWLHGAMRQHGNLTWEARMKIITGTAQALAYLHEAIEPKVVHRDIKASNILID----- 318
Query 749 EGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
KLSD G+ S E + ++APE G L+ D + FG
Sbjct 319 --DEFNAKLSDFGLAKLLDSGESHITTRVMGTFGYVAPEYANTGL--LNEKSDIYSFGVL 374
Query 804 LLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLAT------------LTS 846
LLE + P + E R E P+L ++
Sbjct 375 LLEAITGRDPVDYGRPANEVNLVEWLKMMVGTRRAEEVVDPRLEPRPSKSALKRALLVSL 434
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
+C+ E +RP + R L + +
Sbjct 435 RCVDPEAEKRPRMSQVARMLESDEHPFHKERRNKR 469
>sp|Q60805|MERTK_MOUSE Tyrosine-protein kinase Mer OS=Mus musculus
OX=10090 GN=Mertk PE=1 SV=1
Length=994
Score = 259 bits (663), Expect = 1e-70, Method: Composition-based stats.
Identities = 89/283 (31%), Positives = 134/283 (47%), Gaps = 27/283 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG FG V DGT + VAVK +K D + + E ++ H ++I+
Sbjct 588 LGEGEFGSVMEGNLK-QEDGTSQKVAVKTMKLDNFSQREIEEFLSEAACMKDFNHPNVIR 646
Query 962 YKGCCED---QGEKSLQLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFAQQICEGM 1011
G C + QG +++ ++ G L +L + L LL F I +GM
Sbjct 647 LLGVCIELSSQGIPKPMVILPFMKYGDLHTFLLYSRLNTGPKYIHLQTLLKFMMDIAQGM 706
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
YL ++++HRDLAARN +L +D V + DFGL+K + G +YYR PV W A E
Sbjct 707 EYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQGRIAKMPVKWIAIE 765
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
L + + SDVW+FGVT++E+ T + + + L G
Sbjct 766 SLADRVYTSKSDVWAFGVTMWEITTRG--------------MTPYPGVQNHEMYDYLLHG 811
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
RL +P+ C E+Y +M +CW + RPTF L L+ + E
Sbjct 812 HRLKQPEDCLDELYDIMYSCWSADPLDRPTFSVLRLQLEKLSE 854
Score = 231 bits (589), Expect = 3e-61, Method: Composition-based stats.
Identities = 66/313 (21%), Positives = 120/313 (38%), Gaps = 50/313 (16%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
++L +D+ + LG+G +V EG L+ E G
Sbjct 570 NKLEDVVIDRNLLVLGKVLGEGEFGSVMEGNLKQED---------------------GTS 608
Query 637 LRVVLKV--LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-----GPENIMVTEY 689
+V +K LD F A+ M +H ++ + GVC+ P+ +++ +
Sbjct 609 QKVAVKTMKLDNFSQREIEEFLSEAACMKDFNHPNVIRLLGVCIELSSQGIPKPMVILPF 668
Query 690 VEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+++G L +L R ++ + + +A + YL N+N +H ++ RN +L
Sbjct 669 MKYGDLHTFLLYSRLNTGPKYIHLQTLLKFMMDIAQGMEYLSNRNFLHRDLAARNCML-- 726
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKW 798
+ ++D G+ S + + W+A E L ++ D W
Sbjct 727 -----RDDMTVCVADFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRV--YTSKSDVW 779
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
FG T+ EI G P E + HRL PE +L + C + +P R
Sbjct 780 AFGVTMWEITTRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDELYDIMYSCWSADPLDR 839
Query 857 PSFRTILRDLTRL 869
P+F + L +L
Sbjct 840 PTFSVLRLQLEKL 852
>sp|Q62190|RON_MOUSE Macrophage-stimulating protein receptor OS=Mus
musculus OX=10090 GN=Mst1r PE=1 SV=3
Length=1378
Score = 263 bits (671), Expect = 1e-70, Method: Composition-based stats.
Identities = 98/287 (34%), Positives = 143/287 (50%), Gaps = 23/287 (8%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ + + +G+GHFG V Y D + T A+K+L Q + +E
Sbjct 1053 PHEQVVIHTDQVIGKGHFGVVYHGEYTDGAQNQT--HCAIKSLSRITEVQEVEAFLREGL 1110
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQI 1007
++R L+H +I+ G L + Y+ G L ++ P+ + + L+ F Q+
Sbjct 1111 LMRGLHHPNILALIGIMLPPEGLPRVL-LPYMRHGDLLHFIRSPQRNPTVKDLVSFGLQV 1169
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE--DGDSPV 1065
GM YL Q ++HRDLAARN +LD VK+ DFGLA+ V + EYY VR+ PV
Sbjct 1170 ACGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARGVLD-KEYYSVRQHRHARLPV 1228
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
W A E L+ Y+F SDVWSFGV L+ELLT + L+
Sbjct 1229 KWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAP--------------PYPHIDPFDLS 1274
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
L +G RLP+P+ CP +YH+M CWE + + RPTF L+ +K V
Sbjct 1275 HFLAQGRRLPQPEYCPDSLYHVMLRCWEADPAARPTFRALVLEVKQV 1321
Score = 227 bits (578), Expect = 3e-59, Method: Composition-based stats.
Identities = 68/325 (21%), Positives = 126/325 (39%), Gaps = 49/325 (15%)
Query 556 GETSNLIIMRGARASPRTLN---LSQLSFHRVDQKEITQLS--HLGQGTRTNVYEGRLRV 610
+ +++ ++R + L+ L+++ + +++ + +G+G VY G
Sbjct 1021 RDGTSVPLLRTESIRLQDLDRMLLAEVKDVLIPHEQVVIHTDQVIGKGHFGVVYHGEYTD 1080
Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTH 669
+K L + AF LM + H +
Sbjct 1081 GAQNQTHC---------------------AIKSLSRITEVQEVEAFLREGLLMRGLHHPN 1119
Query 670 LAFVHGVCV--RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
+ + G+ + G ++ Y+ HG L ++R + + + + Q+A + YL
Sbjct 1120 ILALIGIMLPPEGLPRVL-LPYMRHGDLLHFIRSPQRNPTVKDLVSFGLQVACGMEYLAE 1178
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER--------IPWL 779
+ VH ++ RN +L S +K++D G+ G L +E R + W+
Sbjct 1179 QKFVHRDLAARNCMLDE-------SFTVKVADFGLARGVLDKEYYSVRQHRHARLPVKWM 1231
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838
A E L +T D W FG L E+ G P P + HF + RLP+P C
Sbjct 1232 ALESLQT--YRFTTKSDVWSFGVLLWELLTRGAPPYPHIDPFDLSHFLAQGRRLPQPEYC 1289
Query 839 PQ-LATLTSQCLTYEPTQRPSFRTI 862
P L + +C +P RP+FR +
Sbjct 1290 PDSLYHVMLRCWEADPAARPTFRAL 1314
>sp|D3ZG83|M3K10_RAT Mitogen-activated protein kinase kinase kinase
10 OS=Rattus norvegicus OX=10116 GN=Map3k10 PE=1 SV=3
Length=940
Score = 259 bits (661), Expect = 1e-70, Method: Composition-based stats.
Identities = 93/341 (27%), Positives = 139/341 (41%), Gaps = 41/341 (12%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
+ + + P N + P L+ +G G FGKV
Sbjct 56 EGWWTGQLPSGRVGVFPSNYVAPAAPAAPTDLQLPQEIPFHELQLEEIIGVGGFGKVYRA 115
Query 915 CYDPTNDGTGEMVAVK--ALKADCGPQHR-SGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
+ GE VAVK L + P +QE + L H +II +G C
Sbjct 116 LWR------GEEVAVKAARLDPERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSP-- 167
Query 972 KSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028
+L LVMEY G+L L + L+ +A Q+ GM YLH IHRDL + N
Sbjct 168 PNLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSIN 227
Query 1029 VLLDN--------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
+L+ D ++KI DFGLA+ + + W APE ++ F
Sbjct 228 ILILEAIENHNLADTVLKITDFGLAR-----EWHKTTKMSAAGTYAWMAPEVIRLSLFSK 282
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
+SDVWSFGV L+ELLT P + ++ + +A G + LP P C
Sbjct 283 SSDVWSFGVLLWELLTG-----EVPYREIDALAVAYG---------VAMNKLTLPIPSTC 328
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
P L++ CW+ + RP F +++ L+ + + Q P
Sbjct 329 PEPFARLLEECWDPDPHGRPDFGSILKQLEVIEQSALFQMP 369
Score = 223 bits (568), Expect = 9e-59, Method: Composition-based stats.
Identities = 79/382 (21%), Positives = 135/382 (35%), Gaps = 44/382 (12%)
Query 527 RELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ 586
+ L +GD+ + + + G + + A A+P L L Q +
Sbjct 40 GDRVQVLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPAAPAAPTDLQLPQ----EIPF 95
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
E+ +G G VY R G+E+ V LDP
Sbjct 96 HELQLEEIIGVGGFGKVYRALWR------------------------GEEVAVKAARLDP 131
Query 647 SHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
A + A L + H ++ + G C+ P +V EY G L L R
Sbjct 132 ERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSPPNLCLVMEYARGGALSRVLAGRR- 190
Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFI-KLSDP 760
VP + A Q+A ++YL N ++H ++ NIL+ + + K++D
Sbjct 191 -VPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDF 249
Query 761 GVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
G+ ++ W+APE + + S + D W FG L E+ GE P +
Sbjct 250 GLAREWHKTTKMSAAGTYAWMAPEVIR--LSLFSKSSDVWSFGVLLWELL-TGEVPYREI 306
Query 819 SPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ + +P A L +C +P RP F +IL+ L ++ L
Sbjct 307 DALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKQLEVIEQSALF 366
Query 876 DVLTVNPDSPASDPTVFHKRYL 897
+ + S D + +
Sbjct 367 QMPLESFHSLQEDWKLEIQHMF 388
>sp|Q17R13|ACK1_BOVIN Activated CDC42 kinase 1 OS=Bos taurus OX=9913
GN=TNK2 PE=1 SV=1
Length=1039
Score = 260 bits (664), Expect = 1e-70, Method: Composition-based stats.
Identities = 108/276 (39%), Positives = 150/276 (54%), Gaps = 21/276 (8%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLY 955
LG+G FG V +D + T VAVK LK D P+ + +E++ + +L
Sbjct 127 HLFEKLGDGSFGVVRRGEWDAPSGKT-VSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLD 185
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAY 1013
H ++I+ G K+ V E PLGSL D L +H L L +A Q+ EGM Y
Sbjct 186 HRNLIRLYGVVLTPPMKT---VTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGY 242
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
L A+ +IHRDLAARN+LL LVKIGDFGL +A+P+ ++Y ++E P W APE L
Sbjct 243 LEAKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESL 302
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
K F +ASD W FGVTL+E+ T+ IG+ Q+ L ++ + GER
Sbjct 303 KTRTFSHASDTWMFGVTLWEMFTYGQEP---------WIGLNGSQI----LHKIDKEGER 349
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
LPRP+ CP ++Y++M CW + RPTF L L
Sbjct 350 LPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFL 385
Score = 225 bits (574), Expect = 3e-59, Method: Composition-based stats.
Identities = 85/353 (24%), Positives = 133/353 (38%), Gaps = 54/353 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ +K++ LG G+ V G G+ + V +K
Sbjct 121 IGEKDLHLFEKLGDGSFGVVRRGEW---------------------DAPSGKTVSVAVKC 159
Query 644 LDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
L P S + F + M + H +L ++GV + P VTE G L LR
Sbjct 160 LKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKT-VTELAPLGSLLDRLR 218
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ +GH + A Q+A + YLE K +H ++ RN+LLA T +K+ D
Sbjct 219 KHQGHFLLGTLSRYAVQVAEGMGYLEAKRFIHRDLAARNLLLA-------TRDLVKIGDF 271
Query 761 GVGLG-------ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ + +E R W APE L + S A D W FG TL E+ G+
Sbjct 272 GLMRALPQNDDHYVMQEHRKVPFAWCAPESLKT--RTFSHASDTWMFGVTLWEMFTYGQE 329
Query 814 PLQSRSPSEKEH-FYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P + S+ H + RLP P CPQ + + QC ++P RP+F + L Q
Sbjct 330 PWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQ 389
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923
P ++ + ++ G+ Y + N T
Sbjct 390 PTDMRALQDFEEPDKLHIQMNDVITVIE----------GRAENYWWRGQNTRT 432
>sp|Q24145|SHARK_DROME Tyrosine-protein kinase Shark OS=Drosophila
melanogaster OX=7227 GN=Shark PE=1 SV=2
Length=939
Score = 258 bits (660), Expect = 1e-70, Method: Composition-based stats.
Identities = 92/275 (33%), Positives = 144/275 (52%), Gaps = 27/275 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEM----VAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
++G G FG V G GE VA+K L + ++ + +E ++ L H+
Sbjct 667 EIGHGEFGSVHSGWL-LRKSGAGEESRLEVAIKMLSDEHS--NKQEFLREASVMMRLEHK 723
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYL 1014
I++ G + L +V E PLGS+ Y+ H + A+L ++A QI GM YL
Sbjct 724 CIVRLIGI---AKGEMLMMVQELAPLGSMLQYILDHGHEITANAELKVWASQIACGMHYL 780
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+QH++HRDLAARN+LL KI DFG+++++ G Y+ + G P+ WYAPE
Sbjct 781 ESQHFVHRDLAARNILLTARHQAKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESFN 840
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
F +ASDVWSFGVT++E+ + G+++ + +L++ GERL
Sbjct 841 LGIFSHASDVWSFGVTIWEMFSLGAP--------------PYGEISNVDAIKLVDSGERL 886
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P+P+ CP +Y +M++CW+ RPTF L
Sbjct 887 PQPNLCPAYIYAVMQSCWKERPKDRPTFVYLTEFF 921
Score = 233 bits (593), Expect = 7e-62, Method: Composition-based stats.
Identities = 74/361 (20%), Positives = 134/361 (37%), Gaps = 43/361 (12%)
Query 520 GRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQL 579
G + ++ + L + + E ++ + R +P T + +++
Sbjct 590 GNGYQPTMDVLSLLDQQIKAPAVARLNSLGPNASTESEMASYL-HRKCSGTPSTPSATEV 648
Query 580 SFHR----VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
+ ++ +++ +G G +V+ G L + G
Sbjct 649 EAAKLRFFIEPEKLVLDREIGHGEFGSVHSGWLLRK-----------------SGAGEES 691
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
L V +K+L H + F AS+M ++ H + + G+ +G +MV E G +
Sbjct 692 RLEVAIKMLSDEHSN-KQEFLREASVMMRLEHKCIVRLIGI-AKGEMLMMVQELAPLGSM 749
Query 696 DVWLRRERGHVPMAWKMVV-AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
++ + ++ V A Q+A + YLE+++ VH ++ RNILL
Sbjct 750 LQYILDHGHEITANAELKVWASQIACGMHYLESQHFVHRDLAARNILLT-------ARHQ 802
Query 755 IKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
K+SD G+ + I W APE G S A D W FG T+ E+
Sbjct 803 AKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESFNLGI--FSHASDVWSFGVTIWEM 860
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRD 865
G P S + RLP+P+ CP + + C P RP+F +
Sbjct 861 FSLGAPPYGEISNVDAIKLVDSGERLPQPNLCPAYIYAVMQSCWKERPKDRPTFVYLTEF 920
Query 866 L 866
Sbjct 921 F 921
Score = 40.0 bits (92), Expect = 0.17, Method: Composition-based stats.
Identities = 21/151 (14%), Positives = 47/151 (31%), Gaps = 8/151 (5%)
Query 450 GIHGPLLEPFVQAKLRP--EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPI 507
HG L L+ EDG +L+ S++ +L++ + + ++R+
Sbjct 10 WYHGNLSREAADELLKQGYEDGTFLVRESSTAAGDFVLSLLCQGEVC----HYQVRRHGG 65
Query 508 EQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA-GDDCFSLRRCCLPQPGETSNLIIMRG 566
E + + + + L Q L R P + + +
Sbjct 66 EDAFFSIDDKVQTKILHGLDTLVDYYQQAANGLPTKLTVPLIRDLPPHNTRSHGVTNLLH 125
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQ 597
RA+ + + + + + GQ
Sbjct 126 -RATSKNESKVVFELLKCGYRNFDAKNQDGQ 155
>sp|O73798|IGF1R_XENLA Insulin-like growth factor 1 receptor OS=Xenopus
laevis OX=8355 GN=igf1r PE=1 SV=1
Length=1358
Score = 263 bits (671), Expect = 1e-70, Method: Composition-based stats.
Identities = 90/309 (29%), Positives = 144/309 (47%), Gaps = 29/309 (9%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE-MVAVKALK 933
+ D + + R+LG+G FG V E VA+K +
Sbjct 973 NPEYFSAAEMYVPDKWEVPREKITMNRELGQGSFGMVYEGIAKGVVKDEAETKVAIKTVN 1032
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991
+ R + E +++ H+++ G QG+ +L ++ME + G L+ YL
Sbjct 1033 EAASMRERIEFLNEASVMKEFNCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSL 1090
Query 992 ---------RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
+ + L +++ A +I +GM+YL+A ++HRDLAARN ++ D VKIGDF
Sbjct 1091 RPDTESNSGQPTPSLKKMIQMAGEIADGMSYLNANKFVHRDLAARNCMVTEDFTVKIGDF 1150
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
G+ + + E +YYR G PV W +PE LK+ F SDVWSFGV L+E+ T
Sbjct 1151 GMTRDIYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTTNSDVWSFGVVLWEIAT------ 1203
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
L M+ ++ + G L +PD CP ++ LM+ CW+ RP+F
Sbjct 1204 --------LAEQPYQGMSNEQVLRFVMEGGLLEKPDNCPDMLFELMRMCWQFNPKMRPSF 1255
Query 1163 ENLIPILKT 1171
+I +K
Sbjct 1256 LEIISSIKD 1264
Score = 247 bits (630), Expect = 1e-65, Method: Composition-based stats.
Identities = 71/317 (22%), Positives = 121/317 (38%), Gaps = 49/317 (15%)
Query 567 ARASPRTLNLSQL---SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
A +P + +++ V +++IT LGQG+ VYEG + +
Sbjct 970 ASVNPEYFSAAEMYVPDKWEVPREKITMNRELGQGSFGMVYEGIAKGVVKDEA------- 1022
Query 624 EDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
E +V +K ++ + + F AS+M + + H+ + GV +G
Sbjct 1023 ------------ETKVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQP 1070
Query 683 NIMVTEYVEHGPLDVWLRRERGH---------VPMAWKMVVAQQLASALSYLENKNLVHG 733
+++ E + G L +LR R + + +A ++A +SYL VH
Sbjct 1071 TLVIMELMTRGDLKSYLRSLRPDTESNSGQPTPSLKKMIQMAGEIADGMSYLNANKFVHR 1130
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGG 787
++ RN ++ +K+ D G+ + + + W++PE L G
Sbjct 1131 DLAARNCMVTE-------DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDG 1183
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLT 845
+T D W FG L EI E P Q S + F L P+ L L
Sbjct 1184 V--FTTNSDVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEKPDNCPDMLFELM 1241
Query 846 SQCLTYEPTQRPSFRTI 862
C + P RPSF I
Sbjct 1242 RMCWQFNPKMRPSFLEI 1258
>sp|Q9M8S2|LIPG2_ARATH Receptor-like kinase LIP2 OS=Arabidopsis
thaliana OX=3702 GN=LIP2 PE=1 SV=1
Length=558
Score = 250 bits (638), Expect = 2e-70, Method: Composition-based stats.
Identities = 83/302 (27%), Positives = 133/302 (44%), Gaps = 18/302 (6%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
++ LGEG FG+V Y T TG++VAVK L G ++ E+ L L
Sbjct 63 NFRQECLLGEGGFGRV----YKGTLKSTGQVVAVKQLDKH-GLHGNKEFQAEVLSLGQLD 117
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQICEG 1010
H +++K G C D ++ LV +Y+ GSL+D+L + + A +G
Sbjct 118 HPNLVKLIGYCADGDQR--LLVYDYISGGSLQDHLHEPKADSDPMDWTTRMQIAYAAAQG 175
Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVF 1066
+ YLH + I+RDL A N+LLD+D K+ DFGL K P G + +
Sbjct 176 LDYLHDKANPPVIYRDLKASNILLDDDFSPKLSDFGLHKLGPGTGDKMMALSSRVMGTYG 235
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQG-QMTVLRL 1124
+ APE + SDV+SFGV L EL+T + + P L+ AQ R
Sbjct 236 YSAPEYTRGGNLTLKSDVYSFGVVLLELITGRRALDTTRPNDEQNLVSWAQPIFRDPKRY 295
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
++ + ++ + + C + EAS RP +++ L + + P+
Sbjct 296 PDMADPVLENKFSERGLNQAVAIASMCVQEEASARPLISDVMVALSFLSMPTEDGIPTTV 355
Query 1185 SV 1186
+
Sbjct 356 PI 357
Score = 228 bits (580), Expect = 7e-63, Method: Composition-based stats.
Identities = 75/354 (21%), Positives = 120/354 (34%), Gaps = 68/354 (19%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRV 610
P+P + S T +L +F + K Q LG+G VY+G L+
Sbjct 27 PKPDDRRRAEETEEIEQSEGT-SLKIFTFRELATATKNFRQECLLGEGGFGRVYKGTLKS 85
Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670
G V +K LD F + Q+ H +L
Sbjct 86 TGQ------------------------VVAVKQLDKHGLHGNKEFQAEVLSLGQLDHPNL 121
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER---GHVPMAWKMVVAQQLASALSYLEN 727
+ G C G + ++V +Y+ G L L + + +M +A A L YL +
Sbjct 122 VKLIGYCADGDQRLLVYDYISGGSLQDHLHEPKADSDPMDWTTRMQIAYAAAQGLDYLHD 181
Query 728 K---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR--------EERVERI 776
K +++ ++ NILL KLSD G+ +
Sbjct 182 KANPPVIYRDLKASNILLDDDFSP-------KLSDFGLHKLGPGTGDKMMALSSRVMGTY 234
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ------ 830
+ APE GG +L+ D + FG LLE+ A +R E+ Q
Sbjct 235 GYSAPEYTRGG--NLTLKSDVYSFGVVLLELITGRRALDTTRPNDEQNLVSWAQPIFRDP 292
Query 831 HRLPEPSCPQLAT------------LTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
R P+ + P L + S C+ E + RP ++ L+ L
Sbjct 293 KRYPDMADPVLENKFSERGLNQAVAIASMCVQEEASARPLISDVMVALSFLSMP 346
>sp|Q8MY85|FGFR2_DUGJA Fibroblast growth factor receptor 2 OS=Dugesia
japonica OX=6161 GN=FGFR2 PE=2 SV=1
Length=887
Score = 258 bits (658), Expect = 2e-70, Method: Composition-based stats.
Identities = 95/311 (31%), Positives = 138/311 (44%), Gaps = 38/311 (12%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT-GEMVAVKALKADCGPQHRSGWKQEI 948
+F + L +GEG FG V ++ + VA+K L G Q QE+
Sbjct 578 WIFSRDSLIIGSKIGEGAFGIVYSALVKSFSENSASVEVAIKTLHTSFGDQDVINLIQEL 637
Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------------- 994
++++ + H HII G C D G +V+E G+LRD+L
Sbjct 638 EMMKIIGRHRHIISLYGACIDNGHP--YMVIELAKHGNLRDFLRAQRSQSKVGEIQNSGG 695
Query 995 ----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
+ + L F+ +I EGM YL ++ IHRDLAARNVL+D +KI DFGL + V
Sbjct 696 LVTRLTVTDFLRFSIEIAEGMEYLSSRKIIHRDLAARNVLVDQYVEMKIADFGLTRIV-- 753
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
YYR DG P+ W APECL + + SDVWS+G+ L+E+ T
Sbjct 754 -ENYYRKTTDGRLPIKWMAPECLLDRVYTVKSDVWSYGIVLWEIFT-------------- 798
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ + + + L G R +P E+Y LM W + R TF +I L
Sbjct 799 MGQTPYPTIQSDGMHQALRNGIRNEKPALASDEMYRLMLTIWNDDPLERHTFSEIIDKLT 858
Query 1171 TVHEKYQGQAP 1181
+ G +P
Sbjct 859 HIQLSNGGSSP 869
Score = 216 bits (551), Expect = 8e-57, Method: Composition-based stats.
Identities = 62/333 (19%), Positives = 120/333 (36%), Gaps = 51/333 (15%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ + S +G+G VY ++ + V +
Sbjct 578 WIFSRDSLIIGSKIGEGAFGIVYSALVKSFSENSAS-------------------VEVAI 618
Query 642 KVLDPS-HHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
K L S + + +M + H H+ ++G C+ MV E +HG L +L
Sbjct 619 KTLHTSFGDQDVINLIQELEMMKIIGRHRHIISLYGACIDNGHPYMVIELAKHGNLRDFL 678
Query 700 RRERGH---------------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
R +R + + + + ++A + YL ++ ++H ++ RN+L+ +
Sbjct 679 RAQRSQSKVGEIQNSGGLVTRLTVTDFLRFSIEIAEGMEYLSSRKIIHRDLAARNVLVDQ 738
Query 745 LGLAEGTSPFIKLSDPGVGL--GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGF 800
+K++D G+ R+ R+P W+APECL + D W +
Sbjct 739 YVE-------MKIADFGLTRIVENYYRKTTDGRLPIKWMAPECLLDRV--YTVKSDVWSY 789
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPS 858
G L EI G+ P + + R P + ++ L +P +R +
Sbjct 790 GIVLWEIFTMGQTPYPTIQSDGMHQALRNGIRNEKPALASDEMYRLMLTIWNDDPLERHT 849
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTV 891
F I+ LT +Q N + +S+
Sbjct 850 FSEIIDKLTHIQLSNGGSSPKRDYLEISSNQCY 882
>sp|Q66L42|M3K10_MOUSE Mitogen-activated protein kinase kinase
kinase 10 OS=Mus musculus OX=10090 GN=Map3k10 PE=1 SV=2
Length=940
Score = 258 bits (660), Expect = 2e-70, Method: Composition-based stats.
Identities = 94/341 (28%), Positives = 139/341 (41%), Gaps = 41/341 (12%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
+ + + P N S P L+ +G G FGKV
Sbjct 56 EGWWTGQLPSGRVGVFPSNYVAPAAPAAPSDLQLPQEIPFHELQLEEIIGVGGFGKVYRA 115
Query 915 CYDPTNDGTGEMVAVK--ALKADCGPQHR-SGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
+ GE VAVK L + P +QE + L H +II +G C
Sbjct 116 VWR------GEEVAVKAARLDPERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSP-- 167
Query 972 KSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028
+L LVMEY G+L L + L+ +A Q+ GM YLH IHRDL + N
Sbjct 168 PNLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSIN 227
Query 1029 VLLDN--------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
+L+ D ++KI DFGLA+ + + W APE ++ F
Sbjct 228 ILILEAIENHNLADTVLKITDFGLAR-----EWHKTTKMSAAGTYAWMAPEVIRLSLFSK 282
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
+SDVWSFGV L+ELLT P + ++ + +A G + LP P C
Sbjct 283 SSDVWSFGVLLWELLTG-----EVPYREIDALAVAYG---------VAMNKLTLPIPSTC 328
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
P L++ CW+ + RP F +++ L+ + + Q P
Sbjct 329 PEPFARLLEECWDPDPHGRPDFGSILKQLEVIEQSALFQMP 369
Score = 224 bits (570), Expect = 6e-59, Method: Composition-based stats.
Identities = 79/382 (21%), Positives = 135/382 (35%), Gaps = 44/382 (12%)
Query 527 RELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ 586
+ L +GD+ + + + G + + A A+P L L Q +
Sbjct 40 GDRVQVLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPAAPAAPSDLQLPQ----EIPF 95
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
E+ +G G VY R G+E+ V LDP
Sbjct 96 HELQLEEIIGVGGFGKVYRAVWR------------------------GEEVAVKAARLDP 131
Query 647 SHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
A + A L + H ++ + G C+ P +V EY G L L R
Sbjct 132 ERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSPPNLCLVMEYARGGALSRVLAGRR- 190
Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFI-KLSDP 760
VP + A Q+A ++YL N ++H ++ NIL+ + + K++D
Sbjct 191 -VPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDF 249
Query 761 GVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
G+ ++ W+APE + + S + D W FG L E+ GE P +
Sbjct 250 GLAREWHKTTKMSAAGTYAWMAPEVIR--LSLFSKSSDVWSFGVLLWELL-TGEVPYREI 306
Query 819 SPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ + +P A L +C +P RP F +IL+ L ++ L
Sbjct 307 DALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKQLEVIEQSALF 366
Query 876 DVLTVNPDSPASDPTVFHKRYL 897
+ + S D + +
Sbjct 367 QMPLESFHSLQEDWKLEIQHMF 388
>sp|Q6NKZ9|Y4345_ARATH Probable receptor-like serine/threonine-protein
kinase At4g34500 OS=Arabidopsis thaliana OX=3702 GN=At4g34500
PE=2 SV=1
Length=437
Score = 246 bits (628), Expect = 2e-70, Method: Composition-based stats.
Identities = 73/277 (26%), Positives = 122/277 (44%), Gaps = 17/277 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG +G V + G + AVK L + G Q +K E++ + + H++++
Sbjct 151 IGEGGYGVVYRADF-----SDGSVAAVKNLLNNKG-QAEKEFKVEVEAIGKVRHKNLVGL 204
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQICEGMAYLHA- 1016
G C D + LV EY+ G+L +L + + A +G+AYLH
Sbjct 205 MGYCADSAQSQRMLVYEYIDNGNLEQWLHGDVGPVSPLTWDIRMKIAIGTAKGLAYLHEG 264
Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+HRD+ + N+LLD K+ DFGLAK + G E V + +PE
Sbjct 265 LEPKVVHRDVKSSNILLDKKWNAKVSDFGLAKLL--GSETSYVTTRVMGTFGYVSPEYAS 322
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
SDV+SFGV L E++T S P + L+ +G + R E+++ +
Sbjct 323 TGMLNECSDVYSFGVLLMEIITGRSPVDYSRPPGEMNLVDWFKGMVASRRGEEVIDPKIK 382
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
P + + C + ++S RP +I +L+
Sbjct 383 TSPPPRALKRALLVCLRCIDLDSSKRPKMGQIIHMLE 419
Score = 207 bits (527), Expect = 5e-57, Method: Composition-based stats.
Identities = 65/336 (19%), Positives = 114/336 (34%), Gaps = 64/336 (19%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
L + + + + +G+G VY D
Sbjct 134 SLKDLEIATRGFSDDNMIGEGGYGVVYRA-------------------------DFSDGS 168
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG--PENIMVTEYVEHGPL 695
+K L + F + +V H +L + G C + ++V EY+++G L
Sbjct 169 VAAVKNLLNNKGQAEKEFKVEVEAIGKVRHKNLVGLMGYCADSAQSQRMLVYEYIDNGNL 228
Query 696 DVWLRRERGHV-PMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAE 749
+ WL + G V P+ W +M +A A L+YL +VH +V NILL +
Sbjct 229 EQWLHGDVGPVSPLTWDIRMKIAIGTAKGLAYLHEGLEPKVVHRDVKSSNILLDKK---- 284
Query 750 GTSPFIKLSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
K+SD G+ + + +++PE G L+ D + FG L
Sbjct 285 ---WNAKVSDFGLAKLLGSETSYVTTRVMGTFGYVSPEYASTGM--LNECSDVYSFGVLL 339
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQ-----HRLPEPSCPQLAT------------LTSQ 847
+EI SR P E + R E P++ T + +
Sbjct 340 MEIITGRSPVDYSRPPGEMNLVDWFKGMVASRRGEEVIDPKIKTSPPPRALKRALLVCLR 399
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
C+ + ++RP I+ L + +
Sbjct 400 CIDLDSSKRPKMGQIIHMLEAEDFPFRPEHRSNQER 435
>sp|Q9SY89|Y1661_ARATH Putative G-type lectin S-receptor-like
serine/threonine-protein kinase At1g61610 OS=Arabidopsis thaliana
OX=3702 GN=At1g61610 PE=3 SV=1
Length=842
Score = 257 bits (656), Expect = 2e-70, Method: Composition-based stats.
Identities = 76/278 (27%), Positives = 122/278 (44%), Gaps = 16/278 (6%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG+G FG V + G +AVK L + Q +K EI ++ L H +++
Sbjct 529 NKLGQGGFGTVYKGNF-----SEGREIAVKRL-SGKSKQGLEEFKNEILLIAKLQHRNLV 582
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016
+ GCC + EK L+ EY+P SL +L + S+ + I G+ YLH
Sbjct 583 RLLGCCIEDNEK--MLLYEYMPNKSLDRFLFDESKQGSLDWRKRWEVIGGIARGLLYLHR 640
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRDL A N+LLD + KI DFG+A+ ++ + APE
Sbjct 641 DSRLKIIHRDLKASNILLDTEMNPKISDFGMARIFNYRQDHANT-IRVVGTYGYMAPEYA 699
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
E F SDV+SFGV + E+++ + T LIG A + + E+++ +
Sbjct 700 MEGIFSEKSDVYSFGVLILEIVSGRKNVSFRGTDHGSLIGYAWHLWSQGKTKEMIDPIVK 759
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
R H+ C + RP +++ +L++
Sbjct 760 DTRDVTEAMRCIHVGMLCTQDSVIHRPNMGSVLLMLES 797
Score = 236 bits (602), Expect = 2e-63, Method: Composition-based stats.
Identities = 61/276 (22%), Positives = 102/276 (37%), Gaps = 56/276 (20%)
Query 559 SNLIIMRGARASP---------RTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGR 607
S++I R +SP T +L SF V + + + LGQG VY+G
Sbjct 484 SDIIENRDYSSSPIKVLVGDQVDTPDLPIFSFDSVASATGDFAEENKLGQGGFGTVYKG- 542
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667
+ + + +K L F L++++ H
Sbjct 543 ------------------------NFSEGREIAVKRLSGKSKQGLEEFKNEILLIAKLQH 578
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYL 725
+L + G C+ E +++ EY+ + LD +L E + W+ V +A L YL
Sbjct 579 RNLVRLLGCCIEDNEKMLLYEYMPNKSLDRFLFDESKQGSLDWRKRWEVIGGIARGLLYL 638
Query 726 ENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERI 776
++H ++ NILL T K+SD G+ R++ V
Sbjct 639 HRDSRLKIIHRDLKASNILLD-------TEMNPKISDFGMARIFNYRQDHANTIRVVGTY 691
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
++APE G S D + FG +LEI +
Sbjct 692 GYMAPEYAMEGI--FSEKSDVYSFGVLILEIVSGRK 725
>sp|C0LGD7|Y1684_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g06840 OS=Arabidopsis thaliana OX=3702
GN=At1g06840 PE=1 SV=2
Length=953
Score = 259 bits (661), Expect = 2e-70, Method: Composition-based stats.
Identities = 79/291 (27%), Positives = 127/291 (44%), Gaps = 25/291 (9%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+G+G +GKV G+G +VA+K + Q + EI++L L
Sbjct 623 DNFNSSTQIGQGGYGKVYKGTL-----GSGTVVAIKR-AQEGSLQGEKEFLTEIELLSRL 676
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGM 1011
+H +++ G C+++GE+ LV EY+ G+LRD + + + A L A +G+
Sbjct 677 HHRNLVSLLGFCDEEGEQ--MLVYEYMENGTLRDNISVKLKEPLDFAMRLRIALGSAKGI 734
Query 1012 AYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP----EGHEYYRVREDGDSP 1064
YLH HRD+ A N+LLD+ K+ DFGL++ P EG V
Sbjct 735 LYLHTEANPPIFHRDIKASNILLDSRFTAKVADFGLSRLAPVPDMEGISPQHVSTVVKGT 794
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+ PE ++ SDV+S GV L EL T + I IA ++L
Sbjct 795 PGYLDPEYFLTHQLTDKSDVYSLGVVLLELFTGMQPITHG-KNIVREINIAYESGSILST 853
Query 1125 TELLERGERL-PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ +R+ PD+C + L C E RP+ ++ L+ + E
Sbjct 854 VD-----KRMSSVPDECLEKFATLALRCCREETDARPSMAEVVRELEIIWE 899
Score = 223 bits (568), Expect = 9e-59, Method: Composition-based stats.
Identities = 60/372 (16%), Positives = 118/372 (32%), Gaps = 66/372 (18%)
Query 565 RGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
R ++AS + + ++ + + +GQG VY+G L
Sbjct 599 RSSKASLKIEGVKSFTYAELALATDNFNSSTQIGQGGYGKVYKGTL-------------- 644
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
G V +K F L+S++ H +L + G C E
Sbjct 645 -----------GSGTVVAIKRAQEGSLQGEKEFLTEIELLSRLHHRNLVSLLGFCDEEGE 693
Query 683 NIMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGR 738
++V EY+E+G L + + + + A ++ +A A + YL N + H ++
Sbjct 694 QMLVYEYMENGTLRDNISVKLKEPLDFAMRLRIALGSAKGILYLHTEANPPIFHRDIKAS 753
Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGA-----------LSREERVERIPWLAPECLPGG 787
NILL + K++D G+ A +L PE
Sbjct 754 NILLD-------SRFTAKVADFGLSRLAPVPDMEGISPQHVSTVVKGTPGYLDPEYFLT- 805
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-----------PEP 836
+ L+ D + G LLE+ + ++ + + + P+
Sbjct 806 -HQLTDKSDVYSLGVVLLELFTGMQPITHGKNIVREINIAYESGSILSTVDKRMSSVPDE 864
Query 837 SCPQLATLTSQCLTYE----PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVF 892
+ ATL +C E P+ R + + ++A ++ +
Sbjct 865 CLEKFATLALRCCREETDARPSMAEVVRELEIIWELMPESHVAKTADLSETMTHPSSSSN 924
Query 893 HKRYLKKIRDLG 904
+
Sbjct 925 SSIMKHHYTSMD 936
>sp|Q9NWZ3|IRAK4_HUMAN Interleukin-1 receptor-associated kinase
4 OS=Homo sapiens OX=9606 GN=IRAK4 PE=1 SV=1
Length=460
Score = 246 bits (629), Expect = 2e-70, Method: Composition-based stats.
Identities = 85/374 (23%), Positives = 149/374 (40%), Gaps = 23/374 (6%)
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
+ P + + KE +Q ++P C + TL + E + P + +
Sbjct 99 LLLPDAVPKTANTLPSKEAITVQQKQMP--FCDKDRTLMTPVQNLEQSYMPPDSS-SPEN 155
Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926
L+ + + + +GEG FG V + T
Sbjct 156 KSLEVSDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNT------T 209
Query 927 VAVKALKADCG---PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
VAVK L A + + + QEI ++ HE++++ G D + L LV Y+P
Sbjct 210 VAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDD--LCLVYVYMPN 267
Query 984 GSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
GSL D L + AQ G+ +LH H+IHRD+ + N+LLD KI
Sbjct 268 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKI 327
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGLA+A + + + + APE L+ SD++SFGV L E++T
Sbjct 328 SDFGLARASEKFAQTVMTSRIVGTTA-YMAPEALRGE-ITPKSDIYSFGVVLLEIITGLP 385
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE-VYHLMKNCWETEASF 1158
+ L L + + + + +++ ++ D E +Y + C + +
Sbjct 386 AVDEHREPQLLLDIKEEIEDEEKTIEDYIDK--KMNDADSTSVEAMYSVASQCLHEKKNK 443
Query 1159 RPTFENLIPILKTV 1172
RP + + +L+ +
Sbjct 444 RPDIKKVQQLLQEM 457
Score = 219 bits (559), Expect = 5e-61, Method: Composition-based stats.
Identities = 72/388 (19%), Positives = 140/388 (36%), Gaps = 78/388 (20%)
Query 524 PSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASP--RTLNLSQLSF 581
P + + ++ F + L P + M +SP ++L +S F
Sbjct 106 PKTANTLPSKEAITVQQKQMPFCDKDRTLMTPVQNLEQSYMPPDSSSPENKSLEVSDTRF 165
Query 582 HRVDQKEITQ-------------LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
H E+ + +G+G VY+G +
Sbjct 166 HSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYV-------------------- 205
Query 629 PGRDRGQELRVVLKVL----DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
V +K L D + ++ F + +M++ H +L + G G +
Sbjct 206 ------NNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLC 259
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+V Y+ +G L L G P++W + +AQ A+ +++L + +H ++ NILL
Sbjct 260 LVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL 319
Query 743 ARLGLAEGTSPFIKLSDPGVGLGA------LSREERVERIPWLAPECLPGGANSLSTAMD 796
+ K+SD G+ + + V ++APE L G ++ D
Sbjct 320 DE-------AFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRG---EITPKSD 369
Query 797 KWGFGATLLEICFDGEAPLQSRSPS---------------EKEHFYQRQHRLPEPSCPQL 841
+ FG LLEI A + R P +++ ++ + S +
Sbjct 370 IYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAM 429
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRL 869
++ SQCL + +RP + + + L +
Sbjct 430 YSVASQCLHEKKNKRPDIKKVQQLLQEM 457
>sp|Q62956|ERBB4_RAT Receptor tyrosine-protein kinase erbB-4 OS=Rattus
norvegicus OX=10116 GN=Erbb4 PE=1 SV=3
Length=1308
Score = 262 bits (669), Expect = 2e-70, Method: Composition-based stats.
Identities = 98/272 (36%), Positives = 140/272 (51%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + VA+K L GP+ + E I+ ++ H H+++
Sbjct 724 LGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASVDHPHLVRL 783
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C +QLV + +P G L +Y+ H IG LL + QI +GM YL + +
Sbjct 784 LGVCLSPT---IQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV 840
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ + VKI DFGLA+ + EG E + G P+ W A EC+ KF +
Sbjct 841 HRDLAARNVLVKSPNHVKITDFGLARLL-EGDEKEYNADGGKMPIKWMALECIHYRKFTH 899
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T G + + +LLE+GERLP+P C
Sbjct 900 QSDVWSYGVTIWELMTFG--------------GKPYDGIPTREIPDLLEKGERLPQPPIC 945
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW +A RP F+ L +
Sbjct 946 TIDVYIVMVKCWMIDADSRPKFKELAAEFSRM 977
Score = 241 bits (615), Expect = 1e-63, Method: Composition-based stats.
Identities = 68/338 (20%), Positives = 131/338 (39%), Gaps = 39/338 (12%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P +Q + + E+ ++ LG G VY+G EG
Sbjct 699 TPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETV-------------- 744
Query 630 GRDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ V +K+L+ + + F + A +M+ V H HL + GVC+ P +VT+
Sbjct 745 ------KIPVAIKILNETTGPKANVEFMDEALIMASVDHPHLVRLLGVCL-SPTIQLVTQ 797
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ HG L ++ + ++ + Q+A + YLE + LVH ++ RN+L+
Sbjct 798 LMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPN-- 855
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+K++D G+ + + I W+A EC+ + D W +G
Sbjct 856 -----HVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIH--YRKFTHQSDVWSYGV 908
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860
T+ E+ G P E ++ RLP+P + + +C + RP F+
Sbjct 909 TIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYIVMVKCWMIDADSRPKFK 968
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898
+ + +R+ ++ D K +
Sbjct 969 ELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQN 1006
>sp|P13388|XMRK_XIPMA Melanoma receptor tyrosine-protein kinase
OS=Xiphophorus maculatus OX=8083 GN=xmrk PE=2 SV=2
Length=1167
Score = 261 bits (666), Expect = 2e-70, Method: Composition-based stats.
Identities = 95/289 (33%), Positives = 143/289 (49%), Gaps = 26/289 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V ++P + VA+K L+ P+ E ++ ++ H H+ +
Sbjct 716 LGSGAFGTVYKGLWNPDGENIRIPVAIKVLREATSPKVNQEVLDEAYVMASVDHPHVCRL 775
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHYI 1020
G C ++QLV + +P G L DY+ +H + LL + QI +GM YL +H +
Sbjct 776 LGICLTS---AVQLVTQLMPYGCLLDYVRQHQERICGQWLLNWCVQIAKGMNYLEERHLV 832
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVLL N VKI DFGL+K + + Y+ + G P+ W A E + ++ + +
Sbjct 833 HRDLAARNVLLKNPNHVKITDFGLSKLLTADEKEYQA-DGGKVPIKWMALESILQWTYTH 891
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + + +LE GERLP+P C
Sbjct 892 QSDVWSYGVTVWELMTFGSK--------------PYDGIPAKEIASVLENGERLPQPPIC 937
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK------YQGQAPSV 1183
EVY ++ CW + S RP F L+ + QG PS+
Sbjct 938 TIEVYMIILKCWMIDPSSRPRFRELVGEFSQMARDPSRYLVIQGNLPSL 986
Score = 237 bits (604), Expect = 1e-62, Method: Composition-based stats.
Identities = 80/454 (18%), Positives = 159/454 (35%), Gaps = 42/454 (9%)
Query 435 CHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAP 494
C + LV + +GP ++ + + + + +
Sbjct 553 CVQCHQECLVQTDSLTCYGPGPANCSKSAHFQDGPQCIPRCPHGILGDGDTLIWKYADKM 612
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
Q G G S S+ + + L R +
Sbjct 613 GQCQPCHQNCTQGCSGPGLSGCRGDIVSHSSLAVGLVSGLLITVIVALLIVVLLRRRRIK 672
Query 555 PGETSNLIIMRGARASPRTL--NLSQLSFHRVDQK-EITQLSHLGQGTRTNVYEGRLRVE 611
T ++ P T +F R+ ++ E + LG G VY+G +
Sbjct 673 RKRTIRCLLQEKELVEPLTPSGQAPNQAFLRILKETEFKKDRVLGSGAFGTVYKGLWNPD 732
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHL 670
G + V +KVL + + + A +M+ V H H+
Sbjct 733 GENI--------------------RIPVAIKVLREATSPKVNQEVLDEAYVMASVDHPHV 772
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730
+ G+C+ +VT+ + +G L ++R+ + + W + Q+A ++YLE ++L
Sbjct 773 CRLLGICLTSAVQ-LVTQLMPYGCLLDYVRQHQERICGQWLLNWCVQIAKGMNYLEERHL 831
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECL 784
VH ++ RN+LL +K++D G+ + E+ + I W+A E +
Sbjct 832 VHRDLAARNVLLKNPN-------HVKITDFGLSKLLTADEKEYQADGGKVPIKWMALESI 884
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--A 842
+ + D W +G T+ E+ G P E + RLP+P +
Sbjct 885 LQ--WTYTHQSDVWSYGVTVWELMTFGSKPYDGIPAKEIASVLENGERLPQPPICTIEVY 942
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
+ +C +P+ RP FR ++ + +++
Sbjct 943 MIILKCWMIDPSSRPRFRELVGEFSQMARDPSRY 976
>sp|D2IYS2|TORSO_BOMMO Tyrosine-protein kinase receptor torso
OS=Bombyx mori OX=7091 GN=tor PE=1 SV=1
Length=807
Score = 256 bits (653), Expect = 2e-70, Method: Composition-based stats.
Identities = 91/334 (27%), Positives = 136/334 (41%), Gaps = 71/334 (21%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
D + +GEG FG V P G+ VAVK LK + ++ E
Sbjct 430 DHWEVRSDRVLLHEVIGEGAFGVVRRGTLAPG----GKSVAVKMLKEFPSQEEVRSFRSE 485
Query 948 IDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--------------- 991
+++++++ H H++ GCC + +V EY G L YL
Sbjct 486 MELMKSVGAHPHVVSLVGCC---SGRKPLIVAEYCSRGDLLSYLRSSWDIIVSKHTAKYY 542
Query 992 ---------------------------------RHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+ LL F +QI GM +L +
Sbjct 543 NNNMDSMDTSKLKVHKEHTKLVVNKLYELQGPCETELTPLDLLSFCRQIAMGMEFLASNR 602
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRDLAARNVL+ D+ +KI DFGL++ + E Y+ + +G PV W A E L +
Sbjct 603 IVHRDLAARNVLVTEDKTLKIADFGLSRDIYE-ENQYKQKGNGKMPVKWMALESLTRRVY 661
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SDVWSFGV ++E++T + G ++ RL L G R+P+P
Sbjct 662 TTQSDVWSFGVVIWEIVT--------------VGGSPYPEVPAARLVRSLRSGYRMPKPV 707
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
C +Y +M+ CW RPTF L L +
Sbjct 708 NCSKPLYDIMRACWNASPRDRPTFPELHQKLDDL 741
Score = 206 bits (523), Expect = 1e-53, Method: Composition-based stats.
Identities = 62/358 (17%), Positives = 109/358 (30%), Gaps = 90/358 (25%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S V + +G+G V G L G
Sbjct 427 SADDHWEVRSDRVLLHEVIGEGAFGVVRRGTLAPGGKS---------------------- 464
Query 637 LRVVLKVLDPS-HHDIALAFYETASLMSQVS-HTHLAFVHGVCVRGPENIMVTEYVEHGP 694
V +K+L + +F LM V H H+ + G C G + ++V EY G
Sbjct 465 --VAVKMLKEFPSQEEVRSFRSEMELMKSVGAHPHVVSLVGCCS-GRKPLIVAEYCSRGD 521
Query 695 LDVWLRRE----------------------------------------------RGHVPM 708
L +LR +
Sbjct 522 LLSYLRSSWDIIVSKHTAKYYNNNMDSMDTSKLKVHKEHTKLVVNKLYELQGPCETELTP 581
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ +Q+A + +L + +VH ++ RN+L+ +K++D G+
Sbjct 582 LDLLSFCRQIAMGMEFLASNRIVHRDLAARNVLVTE-------DKTLKIADFGLSRDIYE 634
Query 769 REERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ ++ + W+A E L +T D W FG + EI G +P +
Sbjct 635 ENQYKQKGNGKMPVKWMALESLTRRV--YTTQSDVWSFGVVIWEIVTVGGSPYPEVPAAR 692
Query 823 KEHFYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ +R+P+ L + C P RP+F + + L L A+
Sbjct 693 LVRSLRSGYRMPKPVNCSKPLYDIMRACWNASPRDRPTFPELHQKLDDLLHSACANEY 750
>sp|Q25410|MIPR_LYMST Putative molluscan insulin-related peptide(s)
receptor OS=Lymnaea stagnalis OX=6523 PE=2 SV=1
Length=1607
Score = 263 bits (671), Expect = 2e-70, Method: Composition-based stats.
Identities = 92/313 (29%), Positives = 148/313 (47%), Gaps = 29/313 (9%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-- 926
+ + + SD + +K I++LG+G FG V D E
Sbjct 1009 MTVISRNMNYVPSEILYISDEWEVDRDKIKLIKELGQGSFGMVYEGVAKGIRDDPNEEIP 1068
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VAVK + R + +E ++ + H++K G + ++ME + LG L
Sbjct 1069 VAVKTVNDRASFSDRREFLKEATTMKEFHCHHVVKLLGVVSTG--QPALVIMELMALGDL 1126
Query 987 RDYLPRHSIGLAQ----------LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036
++YL H +L A +I +GMAYL + ++HRDLAARN ++ +R
Sbjct 1127 KNYLRGHRPDEDHPGVMPPHLLDILQMAGEIADGMAYLADKKFVHRDLAARNCMVSEERT 1186
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
VKIGDFG+ + + E +YYR G PV W APE LK+ F SDVWS+GV ++E++T
Sbjct 1187 VKIGDFGMTRDIYE-TDYYRKGGKGMLPVRWMAPESLKDGVFTSLSDVWSYGVVMWEMVT 1245
Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156
L ++ + + + G + P+ CP E+ +LM++CW +
Sbjct 1246 --------------LAAQPYQGLSNEEVVKFISDGYIMELPENCPNEMAYLMQHCWAKKP 1291
Query 1157 SFRPTFENLIPIL 1169
+ RPTF+ +I L
Sbjct 1292 NQRPTFKAIIEYL 1304
Score = 246 bits (628), Expect = 4e-65, Method: Composition-based stats.
Identities = 69/325 (21%), Positives = 127/325 (39%), Gaps = 44/325 (14%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
+ ++ ++ + L VD+ +I + LGQG+ VYEG +
Sbjct 1006 SDDMTVISRNMNYVPSEILYISDEWEVDRDKIKLIKELGQGSFGMVYEGVAKGIRD---- 1061
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676
D +E+ V +K + D + F + A+ M + H+ + GV
Sbjct 1062 --------------DPNEEIPVAVKTVNDRASFSDRREFLKEATTMKEFHCHHVVKLLGV 1107
Query 677 CVRGPENIMVTEYVEHGPLDVWLRRERGHVP--------MAWKMVVAQQLASALSYLENK 728
G +++ E + G L +LR R + + +A ++A ++YL +K
Sbjct 1108 VSTGQPALVIMELMALGDLKNYLRGHRPDEDHPGVMPPHLLDILQMAGEIADGMAYLADK 1167
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPE 782
VH ++ RN +++ +K+ D G+ + + + W+APE
Sbjct 1168 KFVHRDLAARNCMVSEE-------RTVKIGDFGMTRDIYETDYYRKGGKGMLPVRWMAPE 1220
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQ 840
L G ++ D W +G + E+ P Q S E F + LPE +
Sbjct 1221 SLKDGV--FTSLSDVWSYGVVMWEMVTLAAQPYQGLSNEEVVKFISDGYIMELPENCPNE 1278
Query 841 LATLTSQCLTYEPTQRPSFRTILRD 865
+A L C +P QRP+F+ I+
Sbjct 1279 MAYLMQHCWAKKPNQRPTFKAIIEY 1303
>sp|Q9C5S8|CRK5_ARATH Cysteine-rich receptor-like protein kinase
5 OS=Arabidopsis thaliana OX=3702 GN=CRK5 PE=1 SV=1
Length=659
Score = 252 bits (643), Expect = 3e-70, Method: Composition-based stats.
Identities = 75/282 (27%), Positives = 115/282 (41%), Gaps = 18/282 (6%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
LG+G FG+V G VAVK L G Q +K E+ ++ L H +
Sbjct 342 MCNKLGQGGFGQVYKGTL-----PNGVQVAVKRLSKTSG-QGEKEFKNEVVVVAKLQHRN 395
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYL 1014
++K G C ++ EK LV E+V SL +L + + I G+ YL
Sbjct 396 LVKLLGFCLEREEK--ILVYEFVSNKSLDYFLFDSRMQSQLDWTTRYKIIGGIARGILYL 453
Query 1015 HAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
H IHRDL A N+LLD D K+ DFG+A+ R + +PE
Sbjct 454 HQDSRLTIIHRDLKAGNILLDADMNPKVADFGMARIFEIDQTEAHTRR-VVGTYGYMSPE 512
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLTELLE 1129
+F SDV+SFGV + E+++ +S F L+ + +L++
Sbjct 513 YAMYGQFSMKSDVYSFGVLVLEIISGRKNSSLYQMDASFGNLVTYTWRLWSDGSPLDLVD 572
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
R H+ C + + RPT ++ +L T
Sbjct 573 SSFRDSYQRNEIIRCIHIALLCVQEDTENRPTMSAIVQMLTT 614
Score = 231 bits (590), Expect = 3e-63, Method: Composition-based stats.
Identities = 58/324 (18%), Positives = 109/324 (34%), Gaps = 65/324 (20%)
Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
T Q F ++ + + + LGQG VY+G L
Sbjct 322 TAGSLQFDFKVIEAATDKFSMCNKLGQGGFGQVYKGTLPNG------------------- 362
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
++V +K L + F +++++ H +L + G C+ E I+V E+V
Sbjct 363 ------VQVAVKRLSKTSGQGEKEFKNEVVVVAKLQHRNLVKLLGFCLEREEKILVYEFV 416
Query 691 EHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745
+ LD +L R + W + + +A + YL + ++H ++ NILL
Sbjct 417 SNKSLDYFLFDSRMQSQLDWTTRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNILLD-- 474
Query 746 GLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
K++D G+ V +++PE G S D +
Sbjct 475 -----ADMNPKVADFGMARIFEIDQTEAHTRRVVGTYGYMSPEYAMYG--QFSMKSDVYS 527
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------------QL 841
FG +LEI + + + + RL P +
Sbjct 528 FGVLVLEIISGRKNSSLYQMDASFGNLVTYTWRLWSDGSPLDLVDSSFRDSYQRNEIIRC 587
Query 842 ATLTSQCLTYEPTQRPSFRTILRD 865
+ C+ + RP+ I++
Sbjct 588 IHIALLCVQEDTENRPTMSAIVQM 611
>sp|Q03146|DDR1_MOUSE Epithelial discoidin domain-containing receptor
1 OS=Mus musculus OX=10090 GN=Ddr1 PE=2 SV=2
Length=911
Score = 257 bits (657), Expect = 3e-70, Method: Composition-based stats.
Identities = 98/317 (31%), Positives = 143/317 (45%), Gaps = 45/317 (14%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD------------PTNDGTGEMVAVKALKA 934
F + L+ LGEG FG+V L + + G +VAVK L+
Sbjct 598 PPRVDFPRSRLRFKEKLGEGQFGEVHLCEVEDPQDLVSSDFPISVHKGHPLLVAVKILRP 657
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993
D R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L
Sbjct 658 DATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSARQ 715
Query 994 -------------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034
+I LL QI GM YL +++HRDLA RN L+ +
Sbjct 716 LENKATQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLVGEN 775
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
+KI DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+
Sbjct 776 FTIKIADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEV 834
Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER--LPRPDKCPCEVYHLMKNCW 1152
L C +S P L + + R ++G + L RP CP +Y LM CW
Sbjct 835 LMLC---RSQPFGQLTDEQVIENAGEFFR-----DQGRQVYLSRPPACPQTLYELMLRCW 886
Query 1153 ETEASFRPTFENLIPIL 1169
E RP F L L
Sbjct 887 SREPEQRPPFAQLHRFL 903
Score = 231 bits (588), Expect = 2e-61, Method: Composition-based stats.
Identities = 74/316 (23%), Positives = 123/316 (39%), Gaps = 52/316 (16%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ + LG+G V+ + E+ + +G L V +K+L
Sbjct 604 PRSRLRFKEKLGEGQFGEVH--------LCEVEDPQDLVSSDFPISVHKGHPLLVAVKIL 655
Query 645 DPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---- 699
P A F + +MS++ ++ + GVCV+ M+T+Y+E+G L+ +L
Sbjct 656 RPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSARQ 715
Query 700 --------------RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
+ + + V Q+AS + YL N VH ++ RN L+
Sbjct 716 LENKATQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLV--- 772
Query 746 GLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWG 799
G + IK++D G+ + + V I W+A EC+ G +TA D W
Sbjct 773 ----GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG--KFTTASDVWA 826
Query 800 FGATLLEI-CFDGEAPLQSRSPSEKE----HFYQRQHRL-----PEPSCPQLATLTSQCL 849
FG TL E+ P + + F++ Q R P L L +C
Sbjct 827 FGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQTLYELMLRCW 886
Query 850 TYEPTQRPSFRTILRD 865
+ EP QRP F + R
Sbjct 887 SREPEQRPPFAQLHRF 902
>sp|Q9SYS3|CRK40_ARATH Cysteine-rich receptor-like protein kinase
40 OS=Arabidopsis thaliana OX=3702 GN=CRK40 PE=2 SV=1
Length=654
Score = 252 bits (643), Expect = 3e-70, Method: Composition-based stats.
Identities = 77/305 (25%), Positives = 121/305 (40%), Gaps = 24/305 (8%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933
+D V LG+G FG V + G+ VAVK L
Sbjct 325 YSDSDGQFMLRFDLGMIVMATDDFSSENTLGQGGFGTVYKGTF-----PNGQEVAVKRLT 379
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--- 990
G Q +K E+ +L L H++++K G C + E+ LV E+VP SL ++
Sbjct 380 KGSG-QGDMEFKNEVSLLTRLQHKNLVKLLGFCNEGDEE--ILVYEFVPNSSLDHFIFDE 436
Query 991 -PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
R + + I G+ YLH IHRDL A N+LLD + K+ DFG A+
Sbjct 437 DKRSLLTWEVRFRIIEGIARGLLYLHEDSQLKIIHRDLKASNILLDAEMNPKVADFGTAR 496
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD--SSQSP 1104
+ + APE L + SDV+SFGV L E+++ S +
Sbjct 497 LFDSDETRAETKRIA-GTRGYMAPEYLNHGQISAKSDVYSFGVMLLEMISGERNNSFEGE 555
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+G+ ++ L+E P ++ + C + ++ RPT +
Sbjct 556 GLAAFAWKRWVEGKPEIIIDPFLIEN------PRNEIIKLIQIGLLCVQENSTKRPTMSS 609
Query 1165 LIPIL 1169
+I L
Sbjct 610 VIIWL 614
Score = 239 bits (609), Expect = 8e-66, Method: Composition-based stats.
Identities = 63/305 (21%), Positives = 106/305 (35%), Gaps = 57/305 (19%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ + + + LGQG VY+G V +K
Sbjct 343 MATDDFSSENTLGQGGFGTVYKGTFPNGQ-------------------------EVAVKR 377
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
L + F SL++++ H +L + G C G E I+V E+V + LD ++ E
Sbjct 378 LTKGSGQGDMEFKNEVSLLTRLQHKNLVKLLGFCNEGDEEILVYEFVPNSSLDHFIFDED 437
Query 704 GHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ W + + + +A L YL ++H ++ NILL K++
Sbjct 438 KRSLLTWEVRFRIIEGIARGLLYLHEDSQLKIIHRDLKASNILLD-------AEMNPKVA 490
Query 759 DPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
D G S E R ++APE L G +S D + FG LLE+
Sbjct 491 DFGTARLFDSDETRAETKRIAGTRGYMAPEYLNHG--QISAKSDVYSFGVMLLEMISGER 548
Query 813 ----------APLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860
A R K + P +L + C+ T+RP+
Sbjct 549 NNSFEGEGLAAFAWKRWVEGKPEIIIDPFLIENPRNEIIKLIQIGLLCVQENSTKRPTMS 608
Query 861 TILRD 865
+++
Sbjct 609 SVIIW 613
>sp|P0C5E2|LRL12_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE
PROTEIN KINASE-like 1.2 OS=Arabidopsis thaliana
OX=3702 GN=LRK10L-1.2 PE=2 SV=3
Length=651
Score = 251 bits (642), Expect = 3e-70, Method: Composition-based stats.
Identities = 78/313 (25%), Positives = 131/313 (42%), Gaps = 18/313 (6%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
+ + ++LG+G FG V G VAVK L D +
Sbjct 327 HIFSYEELEEATNNFDPSKELGDGGFGTVYYGKLK-----DGRSVAVKRL-YDNNFKRAE 380
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGL 997
++ E++IL L H +++ G C + + L LV EYV G+L D+L S+
Sbjct 381 QFRNEVEILTGLRHPNLVALFG-CSSKQSRDLLLVYEYVANGTLADHLHGPQANPSSLPW 439
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ L A + + YLHA IHRD+ + N+LLD + VK+ DFGL++ P +
Sbjct 440 SIRLKIAVETASALKYLHASKIIHRDVKSNNILLDQNFNVKVADFGLSRLFPMDKTHVST 499
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQ 1116
G + P+ Y+ SDV+SF V L EL++ + + P + + L +A
Sbjct 500 APQG--TPGYVDPDYHLCYQLSNKSDVYSFAVVLMELISSLPAVDITRPRQEINLSNMAV 557
Query 1117 GQMTVLRLTELLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
++ L ++++ R + V L C +++ RP ++ L +
Sbjct 558 VKIQNHELRDMVDPSLGFDTDTRVRQTVIAVAELAFQCLQSDKDLRPCMSHVQDTLTRIQ 617
Query 1174 EKYQGQAPSVFSV 1186
G V V
Sbjct 618 NNGFGSEMDVVDV 630
Score = 219 bits (557), Expect = 6e-59, Method: Composition-based stats.
Identities = 69/358 (19%), Positives = 121/358 (34%), Gaps = 63/358 (18%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
+++ LG G VY G+L+ S
Sbjct 326 VHIFSYEELEEATNNFDPSKELGDGGFGTVYYGKLKDGRS-------------------- 365
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEH 692
V +K L ++ A F +++ + H +L + G + + ++V EYV +
Sbjct 366 -----VAVKRLYDNNFKRAEQFRNEVEILTGLRHPNLVALFGCSSKQSRDLLLVYEYVAN 420
Query 693 GPLDVWLRR---ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
G L L +P + ++ +A + ASAL YL ++H +V NILL +
Sbjct 421 GTLADHLHGPQANPSSLPWSIRLKIAVETASALKYLHASKIIHRDVKSNNILLDQ----- 475
Query 750 GTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+ +K++D G+ + V ++ P+ LS D + F L
Sbjct 476 --NFNVKVADFGLSRLFPMDKTHVSTAPQGTPGYVDPDY--HLCYQLSNKSDVYSFAVVL 531
Query 805 LEICF-----DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL---------------ATL 844
+E+ D P Q + S + H L + P L A L
Sbjct 532 MELISSLPAVDITRPRQEINLSNMAVVKIQNHELRDMVDPSLGFDTDTRVRQTVIAVAEL 591
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902
QCL + RP + LTR+Q + + V + + + D
Sbjct 592 AFQCLQSDKDLRPCMSHVQDTLTRIQNNGFGSEMDVVDVNKSGPLVAQSPDSVIVKWD 649
>sp|Q9FID9|Y5389_ARATH Probable receptor-like protein kinase At5g38990
OS=Arabidopsis thaliana OX=3702 GN=At5g38990 PE=2 SV=1
Length=880
Score = 256 bits (655), Expect = 3e-70, Method: Composition-based stats.
Identities = 81/347 (23%), Positives = 140/347 (40%), Gaps = 20/347 (6%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
T +P+ S+ +L + + + + + ++ +G G FG
Sbjct 478 TNKPSTNSSWGPLLHGTGSTNTKSASSLPSDLCRRFSIYEIKSATNDFEEKLIIGVGGFG 537
Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
V Y DG +VAVK L+ Q + E+++L L H H++ G C+D
Sbjct 538 SV----YKGRIDGGATLVAVKRLEI-TSNQGAKEFDTELEMLSKLRHVHLVSLIGYCDDD 592
Query 970 GEKSLQLVMEYVPLGSLRDYLPRH------SIGLAQLLLFAQQICEGMAYLHAQH---YI 1020
E + LV EY+P G+L+D+L R + + L G+ YLH I
Sbjct 593 NE--MVLVYEYMPHGTLKDHLFRRDKASDPPLSWKRRLEICIGAARGLQYLHTGAKYTII 650
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ N+LLD + + K+ DFGL++ P V + PE +
Sbjct 651 HRDIKTTNILLDENFVAKVSDFGLSRVGPTSASQTHVSTVVKGTFGYLDPEYYRRQILTE 710
Query 1081 ASDVWSFGVTLYELL-THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SDV+SFGV L E+L QS P + +LI + + ++++
Sbjct 711 KSDVYSFGVVLLEVLCCRPIRMQSVPPEQADLIRWVKSNFNKRTVDQIIDSDLTADITST 770
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILK---TVHEKYQGQAPSV 1183
+ + C + RP +++ L+ +HE + + +V
Sbjct 771 SMEKFCEIAIRCVQDRGMERPPMNDVVWALEFALQLHETAKKKNDNV 817
Score = 224 bits (571), Expect = 2e-59, Method: Composition-based stats.
Identities = 69/382 (18%), Positives = 133/382 (35%), Gaps = 53/382 (14%)
Query 564 MRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
+ A + P L + S + + + + +G G +VY+GR+
Sbjct 499 TKSASSLPSDL-CRRFSIYEIKSATNDFEEKLIIGVGGFGSVYKGRI------------- 544
Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
G V +K L+ + + A F ++S++ H HL + G C
Sbjct 545 -----------DGGATLVAVKRLEITSNQGAKEFDTELEMLSKLRHVHLVSLIGYCDDDN 593
Query 682 ENIMVTEYVEHGPLDVWLRRERG--HVPMAW--KMVVAQQLASALSYLE---NKNLVHGN 734
E ++V EY+ HG L L R P++W ++ + A L YL ++H +
Sbjct 594 EMVLVYEYMPHGTLKDHLFRRDKASDPPLSWKRRLEICIGAARGLQYLHTGAKYTIIHRD 653
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-------ERIPWLAPECLPGG 787
+ NILL + K+SD G+ + + +L PE
Sbjct 654 IKTTNILLDE-------NFVAKVSDFGLSRVGPTSASQTHVSTVVKGTFGYLDPEYYRRQ 706
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLT 845
L+ D + FG LLE+ +QS P + + + + + Q+ + LT
Sbjct 707 I--LTEKSDVYSFGVVLLEVLCCRPIRMQSVPPEQADLIRWVKSNFNKRTVDQIIDSDLT 764
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLAD-VLTVNPDSPASDPTVFHKRYLKKIRDLG 904
+ + + ++ + D V + + ++ + +
Sbjct 765 ADITSTSMEKFCEIAIRCVQDRGMERPPMNDVVWALEFALQLHETAKKKNDNVESLDLMP 824
Query 905 EGHFGKVSLYCYDPTNDGTGEM 926
G G + D + TG +
Sbjct 825 SGEVGTTTDGEDDLFSRTTGHV 846
>sp|H2KZU7|SVH2_CAEEL Tyrosine-protein kinase receptor svh-2 OS=Caenorhabditis
elegans OX=6239 GN=svh-2 PE=1 SV=1
Length=1086
Score = 259 bits (662), Expect = 3e-70, Method: Composition-based stats.
Identities = 89/279 (32%), Positives = 136/279 (49%), Gaps = 20/279 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+GH+G V Y P+ E V K LK S + +E + H +I+K
Sbjct 741 IGQGHYGVVYKAMYSPS-KSLEEKVVCKYLK----EGKISEFYEEARTMSEFDHPNILKL 795
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G D ++ EY+ G L+ ++ ++I + L FA I +GM Y+H++ +I
Sbjct 796 IGVALDDSSHLPIIITEYMAKGDLKSFIENVENTIKMRDLFEFAFDIAKGMNYMHSKKFI 855
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLA RN LLD VKI DFGL + V E Y + D PV W+ PE + E F
Sbjct 856 HRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERDLPVRWFPPE-ISEQGFGI 914
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SD+WSFGV ++EL T + S ++ ++ + T RL +P C
Sbjct 915 TSDIWSFGVVIWELFTRGSTPYSNMASWILILPWLKESETN-----------RLRKPPYC 963
Query 1141 PCEVY-HLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P ++Y +M CW+ + RP F +L+ I+ V + +G
Sbjct 964 PEKLYTDVMLACWKANPAERPQFSDLVTIIPNVVKYMEG 1002
Score = 212 bits (539), Expect = 9e-55, Method: Composition-based stats.
Identities = 63/315 (20%), Positives = 113/315 (36%), Gaps = 51/315 (16%)
Query 583 RVDQKEIT--QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
+VD K + +L +GQG VY+ + E +VV
Sbjct 727 KVDFKNLRVDKLDPIGQGHYGVVYKAM---------------------YSPSKSLEEKVV 765
Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI--MVTEYVEHGPLDVW 698
K L FYE A MS+ H ++ + GV + ++ ++TEY+ G L +
Sbjct 766 CKYLKEGK---ISEFYEEARTMSEFDHPNILKLIGVALDDSSHLPIIITEYMAKGDLKSF 822
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ + M A +A ++Y+ +K +H ++ RN LL +K++
Sbjct 823 IENVENTIKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDE-------HLRVKIA 875
Query 759 DPGVGLGA-------LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
D G+ + ER + W PE G D W FG + E+ G
Sbjct 876 DFGLCRKVDIETELYVQMHERDLPVRWFPPEISEQG---FGITSDIWSFGVVIWELFTRG 932
Query 812 EAPLQSRSPSEKEHFYQR-----QHRLPEPSCPQLAT-LTSQCLTYEPTQRPSFRTILRD 865
P + + + + + R P +L T + C P +RP F ++
Sbjct 933 STPYSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACWKANPAERPQFSDLVTI 992
Query 866 LTRLQPHNLADVLTV 880
+ + + +
Sbjct 993 IPNVVKYMEGYDRSQ 1007
>sp|D7UPN3|RLK10_ORYSJ LysM domain receptor-like kinase 10 OS=Oryza
sativa subsp. japonica OX=39947 GN=RLK10 PE=2 SV=1
Length=605
Score = 250 bits (639), Expect = 3e-70, Method: Composition-based stats.
Identities = 74/342 (22%), Positives = 125/342 (37%), Gaps = 28/342 (8%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
+ + + + + + + + +
Sbjct 265 IMFYRWQKFRKATSRPSPEETSHLDDASQAEGIKVERSIEFSYEEIFNATQGFSME-HKI 323
Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963
G+G FG V GE A+K + G Q + E+ +L ++H ++++
Sbjct 324 GQGGFGSVYYAELR------GEKTAIKKM----GMQATQEFLAELKVLTHVHHLNLVRLI 373
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHY- 1019
G C E L LV E++ G+L +L R + A + A G+ YLH
Sbjct 374 GYCV---ENCLFLVYEFIDNGNLSQHLQRTGYAPLSWATRVQIALDSARGLEYLHEHVVP 430
Query 1020 --IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRD+ + N+LLD D KI DFGLAK G + + PE + +
Sbjct 431 VYVHRDIKSANILLDKDFRAKIADFGLAKLTEVGSMSQSLSTRVAGTFGYMPPE-ARYGE 489
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA-------QGQMTVLRLTELLER 1130
DV++FGV LYELL+ + E G+ L EL++
Sbjct 490 VSPKVDVYAFGVVLYELLSAKQAIVRSSESVSESKGLVFLFEEALSAPNPTEALDELIDP 549
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ P ++ L K+C E RPT +++ L +
Sbjct 550 SLQGDYPVDSALKIASLAKSCTHEEPGMRPTMRSVVVALMAL 591
Score = 197 bits (502), Expect = 4e-52, Method: Composition-based stats.
Identities = 76/368 (21%), Positives = 133/368 (36%), Gaps = 79/368 (21%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRV 610
P P ETS+L A ++ + S+ + + + +GQG +VY LR
Sbjct 280 PSPEETSHLDDASQAEGIKVERSI-EFSYEEIFNATQGFSMEHKIGQGGFGSVYYAELRG 338
Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670
E + +K + F +++ V H +L
Sbjct 339 EKT--------------------------AIKKM---GMQATQEFLAELKVLTHVHHLNL 369
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK 728
+ G CV +V E++++G L L+R G+ P++W ++ +A A L YL
Sbjct 370 VRLIGYCVE-NCLFLVYEFIDNGNLSQHLQRT-GYAPLSWATRVQIALDSARGLEYLHEH 427
Query 729 NL---VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSRE---ERVERIPW 778
+ VH ++ NILL + A K++D G+ G++S+ +
Sbjct 428 VVPVYVHRDIKSANILLDKDFRA-------KIADFGLAKLTEVGSMSQSLSTRVAGTFGY 480
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP-----------SEKEHFY 827
+ PE +S +D + FG L E+ +A ++S E
Sbjct 481 MPPEA---RYGEVSPKVDVYAFGVVLYELLSAKQAIVRSSESVSESKGLVFLFEEALSAP 537
Query 828 QRQHRLPEPSCPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
L E P L A+L C EP RP+ R+++ L L +
Sbjct 538 NPTEALDELIDPSLQGDYPVDSALKIASLAKSCTHEEPGMRPTMRSVVVALMALTANTDL 597
Query 876 DVLTVNPD 883
+ +P
Sbjct 598 RDMDYHPF 605
>sp|Q9Z139|ROR1_MOUSE Inactive tyrosine-protein kinase transmembrane
receptor ROR1 OS=Mus musculus OX=10090 GN=Ror1 PE=2 SV=2
Length=937
Score = 257 bits (657), Expect = 3e-70, Method: Composition-based stats.
Identities = 82/291 (28%), Positives = 135/291 (46%), Gaps = 35/291 (12%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+ +LGE FGK+ ++VA+K LK PQ + ++QE ++ L+H +
Sbjct 475 FMEELGECTFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPN 534
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------------------RHSIGLAQL 1000
I+ G E+ + ++ EY+ G L ++L + S+
Sbjct 535 IVCLLGAVTQ--EQPVCMLFEYMNQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDF 592
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
L A QI GM YL + ++H+DLAARN+L+ VKI D GL++ + +YYRV+
Sbjct 593 LHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIY-SADYYRVQSK 651
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
P+ W PE + KF SD+WSFGV L+E+ + +
Sbjct 652 SSLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQ--------------PYYGFS 697
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ E++ + + LP + CP +Y LM CW S RP F+++ L++
Sbjct 698 NQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRS 748
Score = 243 bits (620), Expect = 2e-65, Method: Composition-based stats.
Identities = 74/340 (22%), Positives = 129/340 (38%), Gaps = 62/340 (18%)
Query 549 RCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRL 608
R P G+ + ++ + + + + + LG+ T +Y+G L
Sbjct 441 RQPKPVRGQNVEMSMLNAYKPKSKA--------KELPLSAVRFMEELGECTFGKIYKGHL 492
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSH 667
+PG D Q V +K L ++ F + ASLM+++ H
Sbjct 493 ------------------YLPGMDHAQ--LVAIKTLKDYNNPQQWTEFQQEASLMAELHH 532
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK---------------- 711
++ + G + M+ EY+ G L +L H +
Sbjct 533 PNIVCLLGAVTQEQPVCMLFEYMNQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDF 592
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771
+ +A Q+A+ + YL + VH ++ RNIL+ G +K+SD G+ S +
Sbjct 593 LHIAIQIAAGMEYLSSHFFVHKDLAARNILI-------GEQLHVKISDLGLSREIYSADY 645
Query 772 RVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
I W+ PE + G S+ D W FG L EI G P S E
Sbjct 646 YRVQSKSSLPIRWMPPEAIMYG--KFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIE 703
Query 826 FYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTIL 863
+++ LP P++ +L ++C P++RP F+ I
Sbjct 704 MVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIH 743
>sp|P00534|ERBB_ALV Tyrosine-protein kinase transforming protein
erbB OS=Avian leukosis virus OX=11864 GN=V-ERBB PE=2 SV=2
Length=634
Score = 251 bits (640), Expect = 4e-70, Method: Composition-based stats.
Identities = 91/272 (33%), Positives = 134/272 (49%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + VA+K L+ P+ E ++ ++ + H+ +
Sbjct 138 LGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRL 197
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C +QL+ + +P G L DY+ H IG LL + QI +GM YL + +
Sbjct 198 LGICLTST---VQLITQLMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLV 254
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ + VKI DFGLAK + + Y E G P+ W A E + + +
Sbjct 255 HRDLAARNVLVKTPQHVKITDFGLAKLLGADEKEYHA-EGGKVPIKWMALESILHRIYTH 313
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + ++ +LE+GERLP+P C
Sbjct 314 QSDVWSYGVTVWELMTFGSK--------------PYDGIPASEISSVLEKGERLPQPPIC 359
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW +A RP F LI +
Sbjct 360 TIDVYMIMVKCWMIDADSRPKFRELIAEFSKM 391
Score = 226 bits (575), Expect = 2e-61, Method: Composition-based stats.
Identities = 68/345 (20%), Positives = 136/345 (39%), Gaps = 39/345 (11%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P +Q + + E ++ LG G VY+G EG
Sbjct 113 TPSGEAPNQAHLRILKETEFKKVKVLGSGAFGTVYKGLWIPEGEKV-------------- 158
Query 630 GRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ V +K L + + A +M+ V + H+ + G+C+ ++T+
Sbjct 159 ------KIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQ-LITQ 211
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ +G L ++R + ++ + + Q+A ++YLE + LVH ++ RN+L+
Sbjct 212 LMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLVHRDLAARNVLV------ 265
Query 749 EGTSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGA 802
T +K++D G+ LGA +E E I W+A E + + D W +G
Sbjct 266 -KTPQHVKITDFGLAKLLGADEKEYHAEGGKVPIKWMALESILHRI--YTHQSDVWSYGV 322
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860
T+ E+ G P SE ++ RLP+P + + +C + RP FR
Sbjct 323 TVWELMTFGSKPYDGIPASEISSVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFR 382
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
++ + +++ ++ + K Y + +
Sbjct 383 ELIAEFSKMARDPPRYLVIQGDERMHLPSPTDSKFYRTLMEEEDM 427
>sp|O64778|Y1142_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61420 OS=Arabidopsis thaliana OX=3702
GN=At1g61420 PE=3 SV=2
Length=807
Score = 255 bits (651), Expect = 4e-70, Method: Composition-based stats.
Identities = 81/308 (26%), Positives = 126/308 (41%), Gaps = 17/308 (6%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
D LG+G FG V G+ +AVK L + G Q +
Sbjct 480 DFFDMHTIQTATNNFSISNKLGQGGFGPVYKGKLQ-----DGKEIAVKRLSSSSG-QGKE 533
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLA 998
+ EI ++ L H+++++ GCC + EK L+ E++ SL +L R I
Sbjct 534 EFMNEIVLISKLQHKNLVRILGCCIEGEEK--LLIYEFMLNNSLDTFLFDSRKRLEIDWP 591
Query 999 QLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ L Q I G+ YLH IHRDL N+LLD KI DFGLA+ + +G EY
Sbjct 592 KRLDIIQGIARGIHYLHRDSHLKVIHRDLKVSNILLDEKMNPKISDFGLAR-MYQGTEYQ 650
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGI 1114
+ + APE F SD++SFGV + E+++ S S + LI
Sbjct 651 DNTRRVVGTLGYMAPEYAWTGMFSEKSDIYSFGVLMLEIISGEKISRFSYGKEEKTLIAY 710
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
A +LL++ + C + + + RP L+ +L T +
Sbjct 711 AWESWCDTGGIDLLDKDVADSCRPLEVERCVQIGLLCVQHQPADRPNTLELLSMLTTTSD 770
Query 1175 KYQGQAPS 1182
+ P+
Sbjct 771 LPPPEQPT 778
Score = 236 bits (602), Expect = 9e-64, Method: Composition-based stats.
Identities = 56/261 (21%), Positives = 99/261 (38%), Gaps = 45/261 (17%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L+ + + + + LGQG VY+G+L+
Sbjct 479 LDFFDMHTIQTATNNFSISNKLGQGGFGPVYKGKLQDGK--------------------- 517
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ +K L S F L+S++ H +L + G C+ G E +++ E++ +
Sbjct 518 ----EIAVKRLSSSSGQGKEEFMNEIVLISKLQHKNLVRILGCCIEGEEKLLIYEFMLNN 573
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748
LD +L R + + W ++ + Q +A + YL ++H ++ NILL
Sbjct 574 SLDTFLFDSRKRLEIDWPKRLDIIQGIARGIHYLHRDSHLKVIHRDLKVSNILLDEK--- 630
Query 749 EGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGA 802
K+SD G+ E + V + ++APE G S D + FG
Sbjct 631 ----MNPKISDFGLARMYQGTEYQDNTRRVVGTLGYMAPEYAWTGM--FSEKSDIYSFGV 684
Query 803 TLLEICFDGEAPLQSRSPSEK 823
+LEI + S EK
Sbjct 685 LMLEIISGEKISRFSYGKEEK 705
>sp|O22040|ANP1_ARATH Mitogen-activated protein kinase kinase
kinase ANP1 OS=Arabidopsis thaliana OX=3702 GN=ANP1 PE=1 SV=2
Length=666
Score = 251 bits (642), Expect = 4e-70, Method: Composition-based stats.
Identities = 71/308 (23%), Positives = 137/308 (44%), Gaps = 28/308 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
++ + + +P PA+ + +K + +G G FG V + N +GE++
Sbjct 40 CIRKSKIFIKPSFSPPPPANTVDMAPPISWRKGQLIGRGAFGTVYMGM----NLDSGELL 95
Query 928 AVKAL-------KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
AVK + + H ++E+ +L+ L H +I++Y G + + +L +++E+
Sbjct 96 AVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNIVRYLGTVRE--DDTLNILLEF 153
Query 981 VPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
VP GS+ L + + + + +Q+ G+ YLH +HRD+ N+L+DN +K+
Sbjct 154 VPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHAIMHRDIKGANILVDNKGCIKL 213
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFG +K V E + +P +W APE + + +++D+WS G T+ E++T
Sbjct 214 ADFGASKQVAELATMTGAKSMKGTP-YWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKA 272
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+Q V + + P PD + + C + + R
Sbjct 273 P-------------WSQQYKEVAAIFFIGTTKSHPPIPDTLSSDAKDFLLKCLQEVPNLR 319
Query 1160 PTFENLIP 1167
PT L+
Sbjct 320 PTASELLK 327
Score = 199 bits (506), Expect = 3e-52, Method: Composition-based stats.
Identities = 57/293 (19%), Positives = 99/293 (34%), Gaps = 37/293 (13%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
+ +G+G VY G G + + + + +
Sbjct 70 RKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAH-------------- 115
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
E L+ +SH ++ G ++ E+V G + L + G P +
Sbjct 116 --IQELEEEVKLLKNLSHPNIVRYLGTVREDDTLNILLEFVPGGSISSLL-EKFGPFPES 172
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA--- 766
+QL L YL N ++H ++ G NIL+ G IKL+D G
Sbjct 173 VVRTYTRQLLLGLEYLHNHAIMHRDIKGANILVDNKG-------CIKLADFGASKQVAEL 225
Query 767 ---LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ W+APE + +S S D W G T++E+ G+AP +
Sbjct 226 ATMTGAKSMKGTPYWMAPEVILQTGHSFS--ADIWSVGCTVIEMV-TGKAPWSQQYKEVA 282
Query 824 EHFYQ----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
F+ +P+ +CL P RP+ +L+ + H
Sbjct 283 AIFFIGTTKSHPPIPDTLSSDAKDFLLKCLQEVPNLRPTASELLKHPFVMGKH 335
>sp|P06213|INSR_HUMAN Insulin receptor OS=Homo sapiens OX=9606
GN=INSR PE=1 SV=4
Length=1382
Score = 261 bits (667), Expect = 4e-70, Method: Composition-based stats.
Identities = 94/304 (31%), Positives = 148/304 (49%), Gaps = 29/304 (10%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGP 938
D + + +R+LG+G FG V G E VAVK +
Sbjct 1006 FPCSVYVPDEWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASL 1065
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------- 991
+ R + E +++ H+++ G +G+ +L +VME + G L+ YL
Sbjct 1066 RERIEFLNEASVMKGFTCHHVVRLLGVV-SKGQPTL-VVMELMAHGDLKSYLRSLRPEAE 1123
Query 992 ----RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
R L +++ A +I +GMAYL+A+ ++HRDLAARN ++ +D VKIGDFG+ +
Sbjct 1124 NNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRD 1183
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ E +YYR G PV W APE LK+ F +SD+WSFGV L+E+ +
Sbjct 1184 IYE-TDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITS----------- 1231
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L ++ ++ + + G L +PD CP V LM+ CW+ RPTF ++
Sbjct 1232 ---LAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVN 1288
Query 1168 ILKT 1171
+LK
Sbjct 1289 LLKD 1292
Score = 251 bits (642), Expect = 5e-67, Method: Composition-based stats.
Identities = 100/519 (19%), Positives = 183/519 (35%), Gaps = 82/519 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPF----VQAKLRPED----GLYLIHW-STSHPYRLILTVA 488
V+ + + D I GP+ V + E GL +++ S L +
Sbjct 840 VSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLC 899
Query 489 QRSQAPDGMQSLRLRKFPIEQ-----------------QDGAFVLEGWGRSFPSVREL-- 529
+ + RLR + F + + ++ ++
Sbjct 900 VSRKHFALERGCRLRGLSPGNYSVRIRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIII 959
Query 530 --GAALQGCLLRAGDDCFSLRRCCLPQPGE----TSNLIIMRGARASPRTLNLSQLSFHR 583
+ + G LR+ P +SN + + P ++ +
Sbjct 960 GPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVP--DEWE 1017
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +++IT L LGQG+ VYEG R G+ E RV +K
Sbjct 1018 VSREKITLLRELGQGSFGMVYEGNARDIIKGEA-------------------ETRVAVKT 1058
Query 644 LDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR- 701
++ S + F AS+M + H+ + GV +G ++V E + HG L +LR
Sbjct 1059 VNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSL 1118
Query 702 --------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
R + + +A ++A ++YL K VH ++ RN ++A
Sbjct 1119 RPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAH-------DF 1171
Query 754 FIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+ D G+ + + + W+APE L G +T+ D W FG L EI
Sbjct 1172 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGV--FTTSSDMWSFGVVLWEI 1229
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
E P Q S + F L P+ ++ L C + P RP+F I+
Sbjct 1230 TSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNL 1289
Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
L + +V + + + + + + + ++
Sbjct 1290 LKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMENVP 1328
>sp|Q55A09|Y9963_DICDI Probable serine/threonine-protein kinase
DDB_G0272254 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0272254
PE=3 SV=1
Length=1331
Score = 261 bits (666), Expect = 4e-70, Method: Composition-based stats.
Identities = 78/293 (27%), Positives = 129/293 (44%), Gaps = 42/293 (14%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL---KADCGPQHRSGWKQE 947
+ + +K +++G+GHF KV + G+ VAVK L K + +K E
Sbjct 1067 MINYSDIKIDKEIGKGHFSKVLKGNWK------GKDVAVKKLNSNKDKAREEMIQEFKAE 1120
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--------SIGLAQ 999
+++L +L H +++ G + +VME++P G+L + + +
Sbjct 1121 VELLGSLQHPNLVTCYGYSL----NPMCIVMEFLPSGNLFELIHSKPSEQQQSIKLDSTL 1176
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
+L A I GM +LH ++ IHRDL + N+L+D +KI D G+A+ +
Sbjct 1177 ILAIAFDIARGMQHLHTRNIIHRDLKSSNLLMDKHFNIKIADLGIAR-----ETSFTQTM 1231
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQ 1118
V W APE L+ + +DV+S+ + LYELLT + Q PP L+
Sbjct 1232 TTIGTVAWTAPEILRHESYNQKADVYSYAIVLYELLTGEEPYQGIPPMNAGILVA----- 1286
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+G R PD C L+ CW + + RP+FE + L
Sbjct 1287 ----------SKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITNYLTK 1329
Score = 221 bits (563), Expect = 2e-57, Method: Composition-based stats.
Identities = 55/301 (18%), Positives = 106/301 (35%), Gaps = 53/301 (18%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
S ++ +I +G+G + V +G + + V
Sbjct 1064 SVTMINYSDIKIDKEIGKGHFSKVLKGNWKGKD--------------------------V 1097
Query 640 VLKVL----DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+K L D + ++ F L+ + H +L +G + +V E++ G L
Sbjct 1098 AVKKLNSNKDKAREEMIQEFKAEVELLGSLQHPNLVTCYGYSL--NPMCIVMEFLPSGNL 1155
Query 696 DVWLRRERG------HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
+ + + + +A +A + +L +N++H ++ N+L+ +
Sbjct 1156 FELIHSKPSEQQQSIKLDSTLILAIAFDIARGMQHLHTRNIIHRDLKSSNLLMDK----- 1210
Query 750 GTSPFIKLSDPGVGL--GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
IK++D G+ + + W APE L S + D + + L E+
Sbjct 1211 --HFNIKIADLGIARETSFTQTMTTIGTVAWTAPEILRH--ESYNQKADVYSYAIVLYEL 1266
Query 808 CFDGEAPLQSRSPSEKEHFYQR---QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
GE P Q P + LP+ P L C + +P +RPSF I
Sbjct 1267 L-TGEEPYQGIPPMNAGILVASKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITN 1325
Query 865 D 865
Sbjct 1326 Y 1326
>sp|Q02779|M3K10_HUMAN Mitogen-activated protein kinase kinase
kinase 10 OS=Homo sapiens OX=9606 GN=MAP3K10 PE=1 SV=3
Length=954
Score = 257 bits (657), Expect = 5e-70, Method: Composition-based stats.
Identities = 93/341 (27%), Positives = 138/341 (40%), Gaps = 41/341 (12%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
+ + + P N + P L+ +G G FGKV
Sbjct 56 EGWWTGQLPSGRVGVFPSNYVAPGAPAAPAGLQLPQEIPFHELQLEEIIGVGGFGKVYRA 115
Query 915 CYDPTNDGTGEMVAVK--ALKADCGPQHR-SGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
+ GE VAVK L + P QE + L H +II +G C +
Sbjct 116 LWR------GEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRGACLNP-- 167
Query 972 KSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028
L LVMEY G+L L + L+ +A Q+ GM YLH IHRDL + N
Sbjct 168 PHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSIN 227
Query 1029 VLLDN--------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
+L+ D ++KI DFGLA+ + + W APE ++ F
Sbjct 228 ILILEAIENHNLADTVLKITDFGLAR-----EWHKTTKMSAAGTYAWMAPEVIRLSLFSK 282
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
+SDVWSFGV L+ELLT P + ++ + +A G + LP P C
Sbjct 283 SSDVWSFGVLLWELLTG-----EVPYREIDALAVAYG---------VAMNKLTLPIPSTC 328
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
P L++ CW+ + RP F +++ L+ + + Q P
Sbjct 329 PEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQSALFQMP 369
Score = 221 bits (564), Expect = 4e-58, Method: Composition-based stats.
Identities = 80/382 (21%), Positives = 136/382 (36%), Gaps = 44/382 (12%)
Query 527 RELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ 586
+ L +GD+ + + + G + + GA A+P L L Q +
Sbjct 40 GDRVQVLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPGAPAAPAGLQLPQ----EIPF 95
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
E+ +G G VY R G+E+ V LDP
Sbjct 96 HELQLEEIIGVGGFGKVYRALWR------------------------GEEVAVKAARLDP 131
Query 647 SHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
A + A L + H ++ + G C+ P +V EY G L L R
Sbjct 132 EKDPAVTAEQVCQEARLFGALQHPNIIALRGACLNPPHLCLVMEYARGGALSRVLAGRR- 190
Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFI-KLSDP 760
VP + A Q+A ++YL N ++H ++ NIL+ + + K++D
Sbjct 191 -VPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDF 249
Query 761 GVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
G+ ++ W+APE + + S + D W FG L E+ GE P +
Sbjct 250 GLAREWHKTTKMSAAGTYAWMAPEVIR--LSLFSKSSDVWSFGVLLWELL-TGEVPYREI 306
Query 819 SPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ + +P A L +C +P RP F +IL+ L ++ L
Sbjct 307 DALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQSALF 366
Query 876 DVLTVNPDSPASDPTVFHKRYL 897
+ + S D + +
Sbjct 367 QMPLESFHSLQEDWKLEIQHMF 388
>sp|Q7T2V3|M3K10_XENLA Mitogen-activated protein kinase kinase
kinase 10 OS=Xenopus laevis OX=8355 GN=map3k10 PE=1 SV=1
Length=1005
Score = 258 bits (658), Expect = 5e-70, Method: Composition-based stats.
Identities = 102/403 (25%), Positives = 150/403 (37%), Gaps = 54/403 (13%)
Query 795 MDKWGFGAT--LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYE 852
D +G + L FD E P+ +E R+ L E +
Sbjct 25 SDVQSYGVSNPLWMAVFDYE-------PTAEEELTLRRGDLVEILSKDSTVSGDEGW--- 74
Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVS 912
+ + + P L +G G FGKV
Sbjct 75 -WTGKIKDKVGIFPSNYVVSDDKYTTLTGAPKQCPLPLEIEFDELNLDEIIGVGGFGKVY 133
Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHR---SGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
+ E VAVKA++ D +QE I L H +II G C
Sbjct 134 KGLWR------DEEVAVKAVRHDPDEDINVTAENVRQEAKIFCMLCHPNIIALTGVCLKP 187
Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAA 1026
L LVMEY G L L + L+ +A QI +GM YLH + IHRDL +
Sbjct 188 --PHLCLVMEYARGGPLHRALAGKKVPAHVLVNWAVQIAKGMTYLHNEAIVPIIHRDLGS 245
Query 1027 RNVLLDN--------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
N+L+ ++ + I DFGLA+ + + W APE ++ F
Sbjct 246 SNILILEKAENDDLFNKTLNITDFGLAREWQK-----TTKMSAAGTYAWMAPEVIRLSLF 300
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+SDVWSFGV L+ELLT P + ++ + +A G + LP P
Sbjct 301 SKSSDVWSFGVLLWELLTG-----EVPYREIDALAVAYG---------VAMNKLTLPIPS 346
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
CP +++ CW+ + RPTF ++ L T+ + Q P
Sbjct 347 TCPEPFVRILEACWDPDPHSRPTFSCILEQLTTIEQSAMFQMP 389
Score = 219 bits (559), Expect = 2e-57, Method: Composition-based stats.
Identities = 64/328 (20%), Positives = 121/328 (37%), Gaps = 44/328 (13%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
++ E+ +G G VY+G R E V +K
Sbjct 112 EIEFDELNLDEIIGVGGFGKVYKGLWRDE--------------------------EVAVK 145
Query 643 VLDPSHHD----IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+ + A + A + + H ++ + GVC++ P +V EY GPL
Sbjct 146 AVRHDPDEDINVTAENVRQEAKIFCMLCHPNIIALTGVCLKPPHLCLVMEYARGGPLHRA 205
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGT-SPF 754
L ++ VP + A Q+A ++YL N+ ++H ++ NIL+ + +
Sbjct 206 LAGKK--VPAHVLVNWAVQIAKGMTYLHNEAIVPIIHRDLGSSNILILEKAENDDLFNKT 263
Query 755 IKLSDPGVGL--GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
+ ++D G+ ++ W+APE + + S + D W FG L E+ GE
Sbjct 264 LNITDFGLAREWQKTTKMSAAGTYAWMAPEVIR--LSLFSKSSDVWSFGVLLWELL-TGE 320
Query 813 APLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
P + + + +P + C +P RP+F IL LT +
Sbjct 321 VPYREIDALAVAYGVAMNKLTLPIPSTCPEPFVRILEACWDPDPHSRPTFSCILEQLTTI 380
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYL 897
+ + + + S D + ++
Sbjct 381 EQSAMFQMPLESFHSLQEDWRLEIQQMF 408
>sp|Q9SF86|PCRK1_ARATH Serine/threonine-protein kinase PCRK1 OS=Arabidopsis
thaliana OX=3702 GN=PCRK1 PE=1 SV=1
Length=418
Score = 244 bits (622), Expect = 6e-70, Method: Composition-based stats.
Identities = 78/288 (27%), Positives = 128/288 (44%), Gaps = 13/288 (5%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG FG V D + ++ VAVK L G Q W E++ L + H +++K
Sbjct 90 IGEGGFGCVFRGTVRNLEDSSVKIEVAVKQL-GKRGLQGHKEWVTEVNFLGIVEHTNLVK 148
Query 962 YKGCCEDQGEKSL--QLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAYLHA 1016
G C + E+ + LV EY+P S+ +L S+ L AQ G+ YLH
Sbjct 149 LLGYCAEDDERGIQRLLVYEYMPNRSVEFHLSPRSLTVLTWDLRLRIAQDAARGLTYLHE 208
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ I RD + N+LLD D K+ DFGLA+ + V D + + APE +
Sbjct 209 EMEFQIIFRDFKSSNILLDEDWKAKLSDFGLAR-LGPSEGLTHVSTDVVGTMGYAAPEYI 267
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELL-ERG 1131
+ + SDVW +GV LYEL+T ++ P +L+ + ++ R +L+ +
Sbjct 268 QTGRLTSKSDVWGYGVFLYELITGRRPVDRNRPKGEQKLLEWVRPYLSDTRKFKLILDPR 327
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
P K ++ + C + RP ++ ++ + E G
Sbjct 328 LEGKYPIKSVQKLAVVANRCLVRNSKARPKMSEVLEMVNKIVEASSGN 375
Score = 216 bits (549), Expect = 4e-60, Method: Composition-based stats.
Identities = 67/335 (20%), Positives = 120/335 (36%), Gaps = 62/335 (19%)
Query 569 ASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
S R NL + S + K ++ +G+G V+ G +R
Sbjct 62 VSTRASNLREFSITDLKSATKNFSRSVMIGEGGFGCVFRGTVRNL--------------- 106
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE---- 682
D ++ V +K L + + + V HT+L + G C E
Sbjct 107 ----EDSSVKIEVAVKQLGKRGLQGHKEWVTEVNFLGIVEHTNLVKLLGYCAEDDERGIQ 162
Query 683 NIMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGR 738
++V EY+ + ++ L R + ++ +AQ A L+YL + ++ +
Sbjct 163 RLLVYEYMPNRSVEFHLSPRSLTVLTWDLRLRIAQDAARGLTYLHEEMEFQIIFRDFKSS 222
Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANSLS 792
NILL KLSD G+ S + V + + APE + G L+
Sbjct 223 NILLDE-------DWKAKLSDFGLARLGPSEGLTHVSTDVVGTMGYAAPEYIQTG--RLT 273
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL------------------P 834
+ D WG+G L E+ ++R E++ + L P
Sbjct 274 SKSDVWGYGVFLYELITGRRPVDRNRPKGEQKLLEWVRPYLSDTRKFKLILDPRLEGKYP 333
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
S +LA + ++CL RP +L + ++
Sbjct 334 IKSVQKLAVVANRCLVRNSKARPKMSEVLEMVNKI 368
>sp|O64780|Y1614_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61400 OS=Arabidopsis thaliana OX=3702
GN=At1g61400 PE=3 SV=4
Length=814
Score = 254 bits (650), Expect = 6e-70, Method: Composition-based stats.
Identities = 77/307 (25%), Positives = 119/307 (39%), Gaps = 17/307 (6%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
+ LG G FG V G +AVK L + Q +
Sbjct 487 YFEMNTIQTATNNFSLSNKLGHGGFGSVYKGKLQ-----DGREIAVKRLSS-SSEQGKQE 540
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ 999
+ EI ++ L H ++++ GCC + EK L+ E++ SL ++ R I +
Sbjct 541 FMNEIVLISKLQHRNLVRVLGCCVEGTEK--LLIYEFMKNKSLDTFVFDSKKRLEIDWPK 598
Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
Q I G+ YLH IHRDL N+LLD KI DFGLA+ G EY
Sbjct 599 RFDIIQGIARGLLYLHRDSRLRIIHRDLKVSNILLDEKMNPKISDFGLARMF-HGTEYQD 657
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIA 1115
+ + +PE F SD++SFGV L E+++ S S + L+ A
Sbjct 658 KTRRVVGTLGYMSPEYAWAGVFSEKSDIYSFGVLLLEIISGEKISRFSYGEEGKTLLAYA 717
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
R LL++ + C + + + RP L+ +L T +
Sbjct 718 WECWCGARGVNLLDQALGDSCHPYEVGRCVQIGLLCVQYQPADRPNTLELLSMLTTTSDL 777
Query 1176 YQGQAPS 1182
+ P+
Sbjct 778 PLPKQPT 784
Score = 234 bits (596), Expect = 7e-63, Method: Composition-based stats.
Identities = 53/247 (21%), Positives = 96/247 (39%), Gaps = 45/247 (18%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L +++ + + + LG G +VY+G+L+
Sbjct 485 LEYFEMNTIQTATNNFSLSNKLGHGGFGSVYKGKLQDGR--------------------- 523
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ +K L S F L+S++ H +L V G CV G E +++ E++++
Sbjct 524 ----EIAVKRLSSSSEQGKQEFMNEIVLISKLQHRNLVRVLGCCVEGTEKLLIYEFMKNK 579
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748
LD ++ + + + W + + Q +A L YL ++H ++ NILL
Sbjct 580 SLDTFVFDSKKRLEIDWPKRFDIIQGIARGLLYLHRDSRLRIIHRDLKVSNILLDEK--- 636
Query 749 EGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGA 802
K+SD G+ E + V + +++PE G S D + FG
Sbjct 637 ----MNPKISDFGLARMFHGTEYQDKTRRVVGTLGYMSPEYAWAGV--FSEKSDIYSFGV 690
Query 803 TLLEICF 809
LLEI
Sbjct 691 LLLEIIS 697
>sp|Q22146|FRK1_CAEEL Fer-related kinase 1 OS=Caenorhabditis elegans
OX=6239 GN=frk-1 PE=1 SV=1
Length=390
Score = 243 bits (619), Expect = 6e-70, Method: Composition-based stats.
Identities = 80/325 (25%), Positives = 143/325 (44%), Gaps = 23/325 (7%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
Q + ++ + A P + + + + LGEG FG V +
Sbjct 88 HQESTISELINWHMTTKTPISAASGAKIRRPMERSPWLINHDSIVANKKLGEGAFGDVFI 147
Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
+ G + VAVK ++A+ + R + +E ++R H+H++K G E
Sbjct 148 AEL---DQGGKQEVAVKTMRAEATREARLRFMKEARLMRKYQHKHVVKLIGVAIH--EHP 202
Query 974 LQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033
L +VMEY P GSL +L ++ + L + L F + +G+AYL IHRD+AARN LL
Sbjct 203 LMIVMEYCPNGSLLSHLKKNKVSLIEKLRFTTEAADGIAYLERSKCIHRDIAARNCLLSA 262
Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
+KI DFG++ + + + P+ W APE ++E + + +D+W+FGV ++E
Sbjct 263 KNELKISDFGMS----DNKDEIKDETLEKVPIKWLAPETMQEKVYTHKTDIWTFGVLVWE 318
Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK-NCW 1152
+ + TK +++ R+ PD V ++ CW
Sbjct 319 IYSDGAEPYPGLTKIQTR-------------AKIVVNDYRMKMPDGTHPTVADVVTGTCW 365
Query 1153 ETEASFRPTFENLIPILKTVHEKYQ 1177
+ R T +++ L+ +E +
Sbjct 366 QKNPEKRSTMDSIHKKLREFYESKK 390
Score = 233 bits (593), Expect = 2e-66, Method: Composition-based stats.
Identities = 81/429 (19%), Positives = 152/429 (35%), Gaps = 83/429 (19%)
Query 448 RDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLIL--TVAQRSQAPDGMQSLRLRKF 505
+ HG + + L+ E G +L+ + P +++L +V + R F
Sbjct 21 AEYYHGMVPRQDAEGFLKRE-GDFLVRKTEQMPGKVVLAMSVRVTDELC--------RHF 71
Query 506 PIEQQD--GAFVLEGWGRSFPSVRELGA-ALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562
+ F E + ++ EL + + +RR P
Sbjct 72 MLNMDPTSNKFYFEHTHQE-STISELINWHMTTKTPISAASGAKIRRPMERSP------- 123
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
++ I LG+G +V+ L
Sbjct 124 -------------------WLINHDSIVANKKLGEGAFGDVFIAEL-------------- 150
Query 623 DEDPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
D+G + V +K + + + L F + A LM + H H+ + GV +
Sbjct 151 ---------DQGGKQEVAVKTMRAEATREARLRFMKEARLMRKYQHKHVVKLIGVAIHEH 201
Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
++V EY +G L L++ + V + K+ + A ++YLE +H ++ RN L
Sbjct 202 PLMIVMEYCPNGSLLSHLKKNK--VSLIEKLRFTTEAADGIAYLERSKCIHRDIAARNCL 259
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKW 798
L+ +K+SD G+ ++ I WLAPE + + D W
Sbjct 260 LSAKNE-------LKISDFGMSDNKDEIKDETLEKVPIKWLAPETMQEKV--YTHKTDIW 310
Query 799 GFGATLLEICFDGEAPLQSRSPSE---KEHFYQRQHRLPEPSCPQLATLTS-QCLTYEPT 854
FG + EI DG P + + K + ++P+ + P +A + + C P
Sbjct 311 TFGVLVWEIYSDGAEPYPGLTKIQTRAKIVVNDYRMKMPDGTHPTVADVVTGTCWQKNPE 370
Query 855 QRPSFRTIL 863
+R + +I
Sbjct 371 KRSTMDSIH 379
>sp|Q9FZ36|M3K2_ARATH Mitogen-activated protein kinase kinase
kinase 2 OS=Arabidopsis thaliana OX=3702 GN=ANP2 PE=2 SV=1
Length=651
Score = 251 bits (640), Expect = 6e-70, Method: Composition-based stats.
Identities = 69/295 (23%), Positives = 130/295 (44%), Gaps = 28/295 (9%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-------K 933
S + +K + +G G FG V + N +GE++AVK +
Sbjct 52 QSPPNNSTVQIKPPIRWRKGQLIGRGAFGTVYMGM----NLDSGELLAVKQVLITSNCAS 107
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993
+ H ++E+ +L+ L H +I++Y G + +++L +++E+VP GS+ L +
Sbjct 108 KEKTQAHIQELEEEVKLLKNLSHPNIVRYLGTVRE--DETLNILLEFVPGGSISSLLEKF 165
Query 994 S-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
+ + + Q+ G+ YLH +HRD+ N+L+DN +K+ DFG +K V E
Sbjct 166 GAFPESVVRTYTNQLLLGLEYLHNHAIMHRDIKGANILVDNQGCIKLADFGASKQVAELA 225
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
+ +P +W APE + + +++D+WS G T+ E++T
Sbjct 226 TISGAKSMKGTP-YWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAP------------ 272
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+Q + + + P PD + + C + E + RPT L+
Sbjct 273 -WSQQYKEIAAIFHIGTTKSHPPIPDNISSDANDFLLKCLQQEPNLRPTASELLK 326
Score = 197 bits (500), Expect = 1e-51, Method: Composition-based stats.
Identities = 60/308 (19%), Positives = 102/308 (33%), Gaps = 39/308 (13%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
S N S + + + +G+G VY G G + + +
Sbjct 51 SQSPPNNSTVQIKPPIRW--RKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASK 108
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
+ + E L+ +SH ++ G ++ E+
Sbjct 109 EKTQAH----------------IQELEEEVKLLKNLSHPNIVRYLGTVREDETLNILLEF 152
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
V G + L + G P + QL L YL N ++H ++ G NIL+ G
Sbjct 153 VPGGSISSLL-EKFGAFPESVVRTYTNQLLLGLEYLHNHAIMHRDIKGANILVDNQG--- 208
Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
IKL+D G + W+APE + +S S D W G T
Sbjct 209 ----CIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVILQTGHSFS--ADIWSVGCT 262
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQ----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859
++E+ G+AP + F+ +P+ +CL EP RP+
Sbjct 263 VIEMV-TGKAPWSQQYKEIAAIFHIGTTKSHPPIPDNISSDANDFLLKCLQQEPNLRPTA 321
Query 860 RTILRDLT 867
+L+
Sbjct 322 SELLKHPF 329
>sp|A2VDU3|M3K7_BOVIN Mitogen-activated protein kinase kinase
kinase 7 OS=Bos taurus OX=9913 GN=MAP3K7 PE=2 SV=1
Length=579
Score = 249 bits (635), Expect = 6e-70, Method: Composition-based stats.
Identities = 73/284 (26%), Positives = 115/284 (40%), Gaps = 40/284 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + + VA+K ++++ R + E+ L + H +I+K
Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQH 1018
G C + LVMEY GSL + L A + + Q +G+AYLH+
Sbjct 93 YGACL----NPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148
Query 1019 ---YIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL N+LL V KI DFG A + + W APE +
Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTA------CDIQTHMTNNKGSAAWMAPEVFE 202
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ DV+S+G+ L+E++T + R+ + G R
Sbjct 203 GSNYSEKCDVFSWGIILWEVITRRKPFD-------------EIGGPAFRIMWAVHNGTRP 249
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P P + LM CW + S RP+ E ++ I+ + + G
Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293
Score = 211 bits (536), Expect = 9e-57, Method: Composition-based stats.
Identities = 63/319 (20%), Positives = 116/319 (36%), Gaps = 47/319 (15%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
L+F +D KEI +G+G V + + R +
Sbjct 24 QVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKD------------------------ 59
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K ++ AF +S+V+H ++ ++G C+ +V EY E G L
Sbjct 60 --VAIKQIESESE--RKAFIVELRQLSRVNHPNIVKLYGACL--NPVCLVMEYAEGGSLY 113
Query 697 VWLRRER--GHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT 751
L + A M Q + ++YL + K L+H ++ N+LL G
Sbjct 114 NVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGT---- 169
Query 752 SPFIKLSDPGVGLGA-LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+K+ D G W+APE G ++ S D + +G L E+
Sbjct 170 --VLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITR 225
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE---PSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ + P+ + + P + +L ++C + +P+QRPS I++ +T
Sbjct 226 RKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMT 285
Query 868 RLQPHNLADVLTVNPDSPA 886
L + +
Sbjct 286 HLMRYFPGADEPLQYPCQY 304
>sp|Q62073|M3K7_MOUSE Mitogen-activated protein kinase kinase
kinase 7 OS=Mus musculus OX=10090 GN=Map3k7 PE=1 SV=1
Length=579
Score = 248 bits (634), Expect = 7e-70, Method: Composition-based stats.
Identities = 73/284 (26%), Positives = 115/284 (40%), Gaps = 40/284 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + + VA+K ++++ R + E+ L + H +I+K
Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQH 1018
G C + LVMEY GSL + L A + + Q +G+AYLH+
Sbjct 93 YGACL----NPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148
Query 1019 ---YIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL N+LL V KI DFG A + + W APE +
Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTA------CDIQTHMTNNKGSAAWMAPEVFE 202
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ DV+S+G+ L+E++T + R+ + G R
Sbjct 203 GSNYSEKCDVFSWGIILWEVITRRKPFD-------------EIGGPAFRIMWAVHNGTRP 249
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P P + LM CW + S RP+ E ++ I+ + + G
Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293
Score = 210 bits (535), Expect = 1e-56, Method: Composition-based stats.
Identities = 63/319 (20%), Positives = 116/319 (36%), Gaps = 47/319 (15%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
L+F +D KEI +G+G V + + R +
Sbjct 24 QVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKD------------------------ 59
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K ++ AF +S+V+H ++ ++G C+ +V EY E G L
Sbjct 60 --VAIKQIESESE--RKAFIVELRQLSRVNHPNIVKLYGACL--NPVCLVMEYAEGGSLY 113
Query 697 VWLRRER--GHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT 751
L + A M Q + ++YL + K L+H ++ N+LL G
Sbjct 114 NVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGT---- 169
Query 752 SPFIKLSDPGVGLGA-LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+K+ D G W+APE G ++ S D + +G L E+
Sbjct 170 --VLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITR 225
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE---PSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ + P+ + + P + +L ++C + +P+QRPS I++ +T
Sbjct 226 RKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMT 285
Query 868 RLQPHNLADVLTVNPDSPA 886
L + +
Sbjct 286 HLMRYFPGADEPLQYPCQY 304
>sp|Q7YR43|DDR1_PANTR Epithelial discoidin domain-containing receptor
1 OS=Pan troglodytes OX=9598 GN=DDR1 PE=3 SV=1
Length=909
Score = 256 bits (653), Expect = 8e-70, Method: Composition-based stats.
Identities = 98/315 (31%), Positives = 139/315 (44%), Gaps = 41/315 (13%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD------------PTNDGTGEMVAVKALKA 934
F + L+ LGEG FG+V L D G +VAVK L+
Sbjct 596 PPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRP 655
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993
D R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L H
Sbjct 656 DATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSAHQ 713
Query 994 -------------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034
+I LL A QI GM YL +++HRDLA RN L+ +
Sbjct 714 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN 773
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
+KI DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+
Sbjct 774 FTIKIADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEV 832
Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154
L C + ++I R L RP CP +Y LM CW
Sbjct 833 LMLCRAQPFGQLTDEQVI------ENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSR 886
Query 1155 EASFRPTFENLIPIL 1169
E+ RP F L L
Sbjct 887 ESEQRPPFSQLHRFL 901
Score = 229 bits (584), Expect = 6e-61, Method: Composition-based stats.
Identities = 73/316 (23%), Positives = 123/316 (39%), Gaps = 52/316 (16%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ + LG+G V+ + + ++ +G L V +K+L
Sbjct 602 PRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVR--------KGHPLLVAVKIL 653
Query 645 DPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
P A F + +MS++ ++ + GVCV+ M+T+Y+E+G L+ +L +
Sbjct 654 RPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 713
Query 704 ------------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
+ + VA Q+AS + YL N VH ++ RN L+
Sbjct 714 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV--- 770
Query 746 GLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWG 799
G + IK++D G+ + + V I W+A EC+ G +TA D W
Sbjct 771 ----GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG--KFTTASDVWA 824
Query 800 FGATLLEI-CFDGEAPLQSRSPSEKE----HFYQRQHRL-----PEPSCPQLATLTSQCL 849
FG TL E+ P + + F++ Q R P L L +C
Sbjct 825 FGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCW 884
Query 850 TYEPTQRPSFRTILRD 865
+ E QRP F + R
Sbjct 885 SRESEQRPPFSQLHRF 900
>sp|Q08345|DDR1_HUMAN Epithelial discoidin domain-containing receptor
1 OS=Homo sapiens OX=9606 GN=DDR1 PE=1 SV=1
Length=913
Score = 256 bits (653), Expect = 8e-70, Method: Composition-based stats.
Identities = 98/315 (31%), Positives = 139/315 (44%), Gaps = 41/315 (13%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD------------PTNDGTGEMVAVKALKA 934
F + L+ LGEG FG+V L D G +VAVK L+
Sbjct 600 PPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRP 659
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993
D R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L H
Sbjct 660 DATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSAHQ 717
Query 994 -------------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034
+I LL A QI GM YL +++HRDLA RN L+ +
Sbjct 718 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN 777
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
+KI DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+
Sbjct 778 FTIKIADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEV 836
Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154
L C + ++I R L RP CP +Y LM CW
Sbjct 837 LMLCRAQPFGQLTDEQVI------ENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSR 890
Query 1155 EASFRPTFENLIPIL 1169
E+ RP F L L
Sbjct 891 ESEQRPPFSQLHRFL 905
Score = 229 bits (584), Expect = 6e-61, Method: Composition-based stats.
Identities = 73/316 (23%), Positives = 123/316 (39%), Gaps = 52/316 (16%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ + LG+G V+ + + ++ +G L V +K+L
Sbjct 606 PRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVR--------KGHPLLVAVKIL 657
Query 645 DPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
P A F + +MS++ ++ + GVCV+ M+T+Y+E+G L+ +L +
Sbjct 658 RPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 717
Query 704 ------------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
+ + VA Q+AS + YL N VH ++ RN L+
Sbjct 718 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV--- 774
Query 746 GLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWG 799
G + IK++D G+ + + V I W+A EC+ G +TA D W
Sbjct 775 ----GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG--KFTTASDVWA 828
Query 800 FGATLLEI-CFDGEAPLQSRSPSEKE----HFYQRQHRL-----PEPSCPQLATLTSQCL 849
FG TL E+ P + + F++ Q R P L L +C
Sbjct 829 FGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCW 888
Query 850 TYEPTQRPSFRTILRD 865
+ E QRP F + R
Sbjct 889 SRESEQRPPFSQLHRF 904
>sp|Q0D5R3|CRK6_ORYSJ Cysteine-rich receptor-like protein kinase
6 OS=Oryza sativa subsp. japonica OX=39947 GN=CRK6 PE=1 SV=1
Length=695
Score = 251 bits (642), Expect = 8e-70, Method: Composition-based stats.
Identities = 85/332 (26%), Positives = 140/332 (42%), Gaps = 22/332 (7%)
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
C +RP +T L + D+ +++ + +G+G
Sbjct 319 CWKRIKKRRPEEQTFLSYSV-----SSDDIQSIDSLILDLPTIRVATDDFADTKMIGQGG 373
Query 908 FGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
FG V G+ +AVK L Q K E+ ++ LYH+++++ G C
Sbjct 374 FGMVYKGVL-----PDGQEIAVKRL-CQSSRQGIGELKSELILVAKLYHKNLVRLIGVCL 427
Query 968 DQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYI 1020
+Q EK LV EY+P GSL L + + I G+ YLH +
Sbjct 428 EQQEK--ILVYEYMPNGSLDIVLFDTDKNRELDWGKRFKIINGIARGLQYLHEDSQLKIV 485
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDL A N+LLD D KI DFGLAK G + V + APE +
Sbjct 486 HRDLKASNILLDFDYSPKISDFGLAKIFG-GDQSEDVTNRIAGTYGYMAPEYAMRGNYSI 544
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SDV+SFGV + E++T ++ S + + ++L+ + T + EL++ P +
Sbjct 545 KSDVFSFGVLVLEIITGRRNTGSYDSGQDVDLLNLVWEHWTRGNVVELIDPSMGDHPPIE 604
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ H+ C + + + RPT ++ +L +
Sbjct 605 QMLKCIHIGLLCVQKKPASRPTISSVNIMLSS 636
Score = 230 bits (587), Expect = 1e-62, Method: Composition-based stats.
Identities = 67/379 (18%), Positives = 121/379 (32%), Gaps = 64/379 (17%)
Query 517 EGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL 576
E +V + +L CF + + E + + ++++
Sbjct 289 EKTKNRIGTVLAIVMPAIAAILLMVVACFCCWKRIKKRRPEEQTFLSYSVSSDDIQSIDS 348
Query 577 SQLSFH--RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
L RV + +GQG VY+G L
Sbjct 349 LILDLPTIRVATDDFADTKMIGQGGFGMVYKGVLPDGQ---------------------- 386
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+ +K L S L++++ H +L + GVC+ E I+V EY+ +G
Sbjct 387 ---EIAVKRLCQSSRQGIGELKSELILVAKLYHKNLVRLIGVCLEQQEKILVYEYMPNGS 443
Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAE 749
LD+ L + + W + + +A L YL +VH ++ NILL
Sbjct 444 LDIVLFDTDKNRELDWGKRFKIINGIARGLQYLHEDSQLKIVHRDLKASNILLD------ 497
Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
K+SD G+ ++APE G + S D + FG
Sbjct 498 -FDYSPKISDFGLAKIFGGDQSEDVTNRIAGTYGYMAPEYAMRG--NYSIKSDVFSFGVL 554
Query 804 LLEICFDGEAPLQSRSPSEKEHF-----YQRQHRLPEPSCPQLAT------------LTS 846
+LEI S + + + + + E P + +
Sbjct 555 VLEIITGRRNTGSYDSGQDVDLLNLVWEHWTRGNVVELIDPSMGDHPPIEQMLKCIHIGL 614
Query 847 QCLTYEPTQRPSFRTILRD 865
C+ +P RP+ ++
Sbjct 615 LCVQKKPASRPTISSVNIM 633
>sp|Q9FFW5|PERK8_ARATH Proline-rich receptor-like protein kinase
PERK8 OS=Arabidopsis thaliana OX=3702 GN=PERK8 PE=1 SV=1
Length=681
Score = 251 bits (640), Expect = 9e-70, Method: Composition-based stats.
Identities = 82/332 (25%), Positives = 126/332 (38%), Gaps = 19/332 (6%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
+ P + + + +++ + D + LGEG FG V
Sbjct 296 SSAPPKMRSHSGSDYMYASSDSGMVSNQRSWFSYDELSQVTSGFSEKNLLGEGGFGCVYK 355
Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
G VAVK LK G Q +K E++I+ ++H H++ G C + +
Sbjct 356 GVL-----SDGREVAVKQLKIG-GSQGEREFKAEVEIISRVHHRHLVTLVGYCISEQHR- 408
Query 974 LQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAAR 1027
LV +YVP +L +L R + + A G+AYLH IHRD+ +
Sbjct 409 -LLVYDYVPNNTLHYHLHAPGRPVMTWETRVRVAAGAARGIAYLHEDCHPRIIHRDIKSS 467
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
N+LLDN + DFGLAK E V + APE K +DV+S+
Sbjct 468 NILLDNSFEALVADFGLAKIAQELDLNTHVSTRVMGTFGYMAPEYATSGKLSEKADVYSY 527
Query 1088 GVTLYELLTHCDSSQ-SPPTKFLELIGIAQG----QMTVLRLTELLERGERLPRPDKCPC 1142
GV L EL+T S P L+ A+ + EL++
Sbjct 528 GVILLELITGRKPVDTSQPLGDESLVEWARPLLGQAIENEEFDELVDPRLGKNFIPGEMF 587
Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ C A+ RP ++ L T+ E
Sbjct 588 RMVEAAAACVRHSAAKRPKMSQVVRALDTLEE 619
Score = 222 bits (566), Expect = 6e-60, Method: Composition-based stats.
Identities = 62/308 (20%), Positives = 104/308 (34%), Gaps = 49/308 (16%)
Query 540 AGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQ-LSFHRVD--QKEITQLSHLG 596
+ F+ R P+ S M + S N S+ + ++ + LG
Sbjct 287 SDVVLFNSRSSAPPKMRSHSGSDYMYASSDSGMVSNQRSWFSYDELSQVTSGFSEKNLLG 346
Query 597 QGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFY 656
+G VY+G L V +K L F
Sbjct 347 EGGFGCVYKGVLSDGR-------------------------EVAVKQLKIGGSQGEREFK 381
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVA 715
++S+V H HL + G C+ ++V +YV + L L R + ++ VA
Sbjct 382 AEVEIISRVHHRHLVTLVGYCISEQHRLLVYDYVPNNTLHYHLHAPGRPVMTWETRVRVA 441
Query 716 QQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-------LG 765
A ++YL ++H ++ NILL A ++D G+ L
Sbjct 442 AGAARGIAYLHEDCHPRIIHRDIKSSNILLDNSFEAL-------VADFGLAKIAQELDLN 494
Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
+ ++APE G LS D + +G LLE+ G P+ + P E
Sbjct 495 THVSTRVMGTFGYMAPEYATSG--KLSEKADVYSYGVILLELI-TGRKPVDTSQPLGDES 551
Query 826 FYQRQHRL 833
+ L
Sbjct 552 LVEWARPL 559
>sp|Q9XEC6|CRK36_ARATH Cysteine-rich receptor-like protein kinase
36 OS=Arabidopsis thaliana OX=3702 GN=CRK36 PE=1 SV=1
Length=658
Score = 250 bits (639), Expect = 1e-69, Method: Composition-based stats.
Identities = 81/365 (22%), Positives = 141/365 (39%), Gaps = 20/365 (5%)
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P RSP ++ + ++ R+ +P + + +R +
Sbjct 255 RVPAPPRSPQTRQDYRVKKGRMFQPWSVVVVVFPTGINLAVFVAFVLAYRRMRRRIYTEI 314
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931
+ +D + LG+G FG V +G+ +AVK
Sbjct 315 NKNSDSDGQATLRFDLGMILIATNEFSLENKLGQGGFGSVYKGIL-----PSGQEIAVKR 369
Query 932 LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL- 990
L A Q +K E+ +L L H +++K G C + E+ LV E+VP SL ++
Sbjct 370 L-AGGSGQGELEFKNEVLLLTRLQHRNLVKLLGFCNEGNEE--ILVYEHVPNSSLDHFIF 426
Query 991 ---PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGL 1044
R + + + G+ YLH IHRDL A N+LLD + K+ DFG+
Sbjct 427 DEDKRWLLTWDVRYRIIEGVARGLLYLHEDSQLRIIHRDLKASNILLDAEMNPKVADFGM 486
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
A+ + APE ++ +F SDV+SFGV L E+++ ++
Sbjct 487 ARLFNMDETRGETSR-VVGTYGYMAPEYVRHGQFSAKSDVYSFGVMLLEMISG---EKNK 542
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ L A + L +++ P ++ + C + A+ RPT +
Sbjct 543 NFETEGLPAFAWKRWIEGELESIIDP-YLNENPRNEIIKLIQIGLLCVQENAAKRPTMNS 601
Query 1165 LIPIL 1169
+I L
Sbjct 602 VITWL 606
Score = 238 bits (606), Expect = 2e-65, Method: Composition-based stats.
Identities = 74/427 (17%), Positives = 132/427 (31%), Gaps = 72/427 (17%)
Query 465 RPEDGLYLIHWSTS---HPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGR 521
G + S YR + P +S + R+ GR
Sbjct 225 WDRVGGTVARPSCYFRWDDYRFAGAFDNLERVPAPPRSPQTRQD---------YRVKKGR 275
Query 522 SFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSF 581
F + + A F L + I + + + + L
Sbjct 276 MFQPWSVVVVVFPTGINLAVFVAFVLAYR---RMRRRIYTEINKNSDSDGQATLRFDLGM 332
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ E + + LGQG +VY+G L + +
Sbjct 333 ILIATNEFSLENKLGQGGFGSVYKGILPSGQ-------------------------EIAV 367
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
K L L F L++++ H +L + G C G E I+V E+V + LD ++
Sbjct 368 KRLAGGSGQGELEFKNEVLLLTRLQHRNLVKLLGFCNEGNEEILVYEHVPNSSLDHFIFD 427
Query 702 ERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIK 756
E + W + + + +A L YL ++H ++ NILL K
Sbjct 428 EDKRWLLTWDVRYRIIEGVARGLLYLHEDSQLRIIHRDLKASNILLD-------AEMNPK 480
Query 757 LSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
++D G+ E R V ++APE + G S D + FG LLE+
Sbjct 481 VADFGMARLFNMDETRGETSRVVGTYGYMAPEYVRHG--QFSAKSDVYSFGVMLLEMISG 538
Query 811 GEAPLQ------------SRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPS 858
+ + + P +L + C+ +RP+
Sbjct 539 EKNKNFETEGLPAFAWKRWIEGELESIIDPYLNENPRNEIIKLIQIGLLCVQENAAKRPT 598
Query 859 FRTILRD 865
+++
Sbjct 599 MNSVITW 605
>sp|O73791|TIE2_DANRE Angiopoietin-1 receptor OS=Danio rerio OX=7955
GN=tek PE=1 SV=1
Length=1116
Score = 258 bits (659), Expect = 1e-69, Method: Composition-based stats.
Identities = 103/354 (29%), Positives = 152/354 (43%), Gaps = 40/354 (11%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
L QR + + S + ++ LGEG+F
Sbjct 768 LKRNTLQRRIHSILREEPAVHFSSAPPPHRRSAVVSRSLVFPALQWSDIQFQDVLGEGNF 827
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY-HEHIIKYKGCCE 967
G+V DG AVK +K + E+++L L H++II G CE
Sbjct 828 GQVLKA--RIRKDGLRMDAAVKRMKDYASQDDHRDFAGELEVLCRLGPHKNIIHLLGACE 885
Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFAQQICEG 1010
+G L L +E+ P G+L D+L + ++ QLL F+ + G
Sbjct 886 HRG--YLYLAIEFAPHGNLLDFLRKSRVLETDPAFAIAHRTASTLSSQQLLAFSADVARG 943
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
M+YL + +IHRDLAARNVL+ + + KI DFGL++ G E Y + G PV W A
Sbjct 944 MSYLSQKQFIHRDLAARNVLVGENFVAKIADFGLSR----GQEVYVKKTMGRLPVRWMAI 999
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E L + SDVWS+GV L+E+++ L G MT L E L
Sbjct 1000 ESLNYSVYTTNSDVWSYGVLLWEVVS--------------LGGTPYCGMTCAELYEKLPL 1045
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
G RL +P C EVY LM+ CW + RP+F ++ L + E+ + +
Sbjct 1046 GFRLEKPLNCDDEVYELMQQCWREKPFERPSFSQILLSLGRMLEERKTYVNTTL 1099
Score = 228 bits (581), Expect = 7e-60, Method: Composition-based stats.
Identities = 89/474 (19%), Positives = 163/474 (34%), Gaps = 62/474 (13%)
Query 442 RLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLR 501
R + + P +L L + +T + +L TV ++ +
Sbjct 666 RFQQVEQAQYRQQVELPVQTQQLHMRFQLLGLRPNTGYQLQLW-TVNNMGESAESPPVSL 724
Query 502 LRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQP-----G 556
+ P ++ F G + + G +L A L+R L +
Sbjct 725 MT-LPQQESSALFAAHGHLLLYAILGSAGMTC-CTVLLAFCIVLQLKRNTLQRRIHSILR 782
Query 557 ETSNLIIMRGARASPRTLNLS-QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615
E + R+ +S L F + +I LG+G V + R+R +G
Sbjct 783 EEPAVHFSSAPPPHRRSAVVSRSLVFPALQWSDIQFQDVLGEGNFGQVLKARIRKDGL-- 840
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVS-HTHLAFV 673
+ +K + + D F ++ ++ H ++ +
Sbjct 841 --------------------RMDAAVKRMKDYASQDDHRDFAGELEVLCRLGPHKNIIHL 880
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQL 718
G C + E+ HG L +LR+ R + + + +
Sbjct 881 LGACEHRGYLYLAIEFAPHGNLLDFLRKSRVLETDPAFAIAHRTASTLSSQQLLAFSADV 940
Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA-LSREERVERIP 777
A +SYL K +H ++ RN+L+ G + K++D G+ G + ++ + R+P
Sbjct 941 ARGMSYLSQKQFIHRDLAARNVLV-------GENFVAKIADFGLSRGQEVYVKKTMGRLP 993
Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-- 833
W+A E L + +T D W +G L E+ G P + +E RL
Sbjct 994 VRWMAIESL--NYSVYTTNSDVWSYGVLLWEVVSLGGTPYCGMTCAELYEKLPLGFRLEK 1051
Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
P ++ L QC +P +RPSF IL L R+ V T +
Sbjct 1052 PLNCDDEVYELMQQCWREKPFERPSFSQILLSLGRMLEERKTYVNTTLYEKFTY 1105
>sp|P0C8E4|M3K7_RAT Mitogen-activated protein kinase kinase kinase
7 OS=Rattus norvegicus OX=10116 GN=Map3k7 PE=1 SV=1
Length=606
Score = 249 bits (635), Expect = 1e-69, Method: Composition-based stats.
Identities = 73/284 (26%), Positives = 115/284 (40%), Gaps = 40/284 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + + VA+K ++++ R + E+ L + H +I+K
Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQH 1018
G C + LVMEY GSL + L A + + Q +G+AYLH+
Sbjct 93 YGACL----NPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148
Query 1019 ---YIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL N+LL V KI DFG A + + W APE +
Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTA------CDIQTHMTNNKGSAAWMAPEVFE 202
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ DV+S+G+ L+E++T + R+ + G R
Sbjct 203 GSNYSEKCDVFSWGIILWEVITRRKPFD-------------EIGGPAFRIMWAVHNGTRP 249
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P P + LM CW + S RP+ E ++ I+ + + G
Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293
Score = 211 bits (536), Expect = 1e-56, Method: Composition-based stats.
Identities = 63/319 (20%), Positives = 116/319 (36%), Gaps = 47/319 (15%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
L+F +D KEI +G+G V + + R +
Sbjct 24 QVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKD------------------------ 59
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K ++ AF +S+V+H ++ ++G C+ +V EY E G L
Sbjct 60 --VAIKQIESESE--RKAFIVELRQLSRVNHPNIVKLYGACL--NPVCLVMEYAEGGSLY 113
Query 697 VWLRRER--GHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT 751
L + A M Q + ++YL + K L+H ++ N+LL G
Sbjct 114 NVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGT---- 169
Query 752 SPFIKLSDPGVGLGA-LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+K+ D G W+APE G ++ S D + +G L E+
Sbjct 170 --VLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITR 225
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE---PSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ + P+ + + P + +L ++C + +P+QRPS I++ +T
Sbjct 226 RKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMT 285
Query 868 RLQPHNLADVLTVNPDSPA 886
L + +
Sbjct 286 HLMRYFPGADEPLQYPCQY 304
>sp|Q5RFL3|M3K7_PONAB Mitogen-activated protein kinase kinase
kinase 7 OS=Pongo abelii OX=9601 GN=MAP3K7 PE=2 SV=1
Length=606
Score = 249 bits (635), Expect = 1e-69, Method: Composition-based stats.
Identities = 73/284 (26%), Positives = 115/284 (40%), Gaps = 40/284 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + + VA+K ++++ R + E+ L + H +I+K
Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQH 1018
G C + LVMEY GSL + L A + + Q +G+AYLH+
Sbjct 93 YGACL----NPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148
Query 1019 ---YIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL N+LL V KI DFG A + + W APE +
Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTA------CDIQTHMTNNKGSAAWMAPEVFE 202
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ DV+S+G+ L+E++T + R+ + G R
Sbjct 203 GSNYSEKCDVFSWGIILWEVITRRKPFD-------------EIGGPAFRIMWAVHNGTRP 249
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P P + LM CW + S RP+ E ++ I+ + + G
Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293
Score = 211 bits (536), Expect = 1e-56, Method: Composition-based stats.
Identities = 63/319 (20%), Positives = 116/319 (36%), Gaps = 47/319 (15%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
L+F +D KEI +G+G V + + R +
Sbjct 24 QVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKD------------------------ 59
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K ++ AF +S+V+H ++ ++G C+ +V EY E G L
Sbjct 60 --VAIKQIESESE--RKAFIVELRQLSRVNHPNIVKLYGACL--NPVCLVMEYAEGGSLY 113
Query 697 VWLRRER--GHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT 751
L + A M Q + ++YL + K L+H ++ N+LL G
Sbjct 114 NVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGT---- 169
Query 752 SPFIKLSDPGVGLGA-LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+K+ D G W+APE G ++ S D + +G L E+
Sbjct 170 --VLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITR 225
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE---PSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ + P+ + + P + +L ++C + +P+QRPS I++ +T
Sbjct 226 RKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMT 285
Query 868 RLQPHNLADVLTVNPDSPA 886
L + +
Sbjct 286 HLMRYFPGADEPLQYPCQY 304
>sp|O43318|M3K7_HUMAN Mitogen-activated protein kinase kinase
kinase 7 OS=Homo sapiens OX=9606 GN=MAP3K7 PE=1 SV=1
Length=606
Score = 249 bits (635), Expect = 1e-69, Method: Composition-based stats.
Identities = 73/284 (26%), Positives = 115/284 (40%), Gaps = 40/284 (14%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + + VA+K ++++ R + E+ L + H +I+K
Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQH 1018
G C + LVMEY GSL + L A + + Q +G+AYLH+
Sbjct 93 YGACL----NPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148
Query 1019 ---YIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL N+LL V KI DFG A + + W APE +
Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTA------CDIQTHMTNNKGSAAWMAPEVFE 202
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ DV+S+G+ L+E++T + R+ + G R
Sbjct 203 GSNYSEKCDVFSWGIILWEVITRRKPFD-------------EIGGPAFRIMWAVHNGTRP 249
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P P + LM CW + S RP+ E ++ I+ + + G
Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293
Score = 211 bits (536), Expect = 2e-56, Method: Composition-based stats.
Identities = 63/319 (20%), Positives = 116/319 (36%), Gaps = 47/319 (15%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
L+F +D KEI +G+G V + + R +
Sbjct 24 QVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKD------------------------ 59
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K ++ AF +S+V+H ++ ++G C+ +V EY E G L
Sbjct 60 --VAIKQIESESE--RKAFIVELRQLSRVNHPNIVKLYGACL--NPVCLVMEYAEGGSLY 113
Query 697 VWLRRER--GHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT 751
L + A M Q + ++YL + K L+H ++ N+LL G
Sbjct 114 NVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGT---- 169
Query 752 SPFIKLSDPGVGLGA-LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+K+ D G W+APE G ++ S D + +G L E+
Sbjct 170 --VLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITR 225
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE---PSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ + P+ + + P + +L ++C + +P+QRPS I++ +T
Sbjct 226 RKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMT 285
Query 868 RLQPHNLADVLTVNPDSPA 886
L + +
Sbjct 286 HLMRYFPGADEPLQYPCQY 304
>sp|C0LGE0|Y1765_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g07650 OS=Arabidopsis thaliana OX=3702
GN=At1g07650 PE=1 SV=1
Length=1014
Score = 257 bits (656), Expect = 1e-69, Method: Composition-based stats.
Identities = 79/304 (26%), Positives = 132/304 (43%), Gaps = 23/304 (8%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R +GEG FG V G+++AVK L A +R + EI ++ L
Sbjct 676 DNFDVTRKIGEGGFGSVYKGEL-----SEGKLIAVKQLSAKSRQGNRE-FVNEIGMISAL 729
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQLLLFAQQIC 1008
H +++K GCC + + L LV EY+ L L R + + I
Sbjct 730 QHPNLVKLYGCCVEGNQ--LILVYEYLENNCLSRALFGKDESSRLKLDWSTRKKIFLGIA 787
Query 1009 EGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
+G+ +LH + +HRD+ A NVLLD D KI DFGLAK +G+ + R G +
Sbjct 788 KGLTFLHEESRIKIVHRDIKASNVLLDKDLNAKISDFGLAKLNDDGNTHISTRIAG--TI 845
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQMTVLRL 1124
+ APE +DV+SFGV E+++ ++ PT+ F+ L+ A L
Sbjct 846 GYMAPEYAMRGYLTEKADVYSFGVVALEIVSGKSNTNFRPTEDFVYLLDWAYVLQERGSL 905
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK---TVHEKYQGQAP 1181
EL++ ++ + ++ C + RPT ++ +++ + E +
Sbjct 906 LELVDPTLASDYSEEEAMLMLNVALMCTNASPTLRPTMSQVVSLIEGKTAMQELLSDPSF 965
Query 1182 SVFS 1185
S +
Sbjct 966 STVN 969
Score = 225 bits (573), Expect = 4e-59, Method: Composition-based stats.
Identities = 67/367 (18%), Positives = 126/367 (34%), Gaps = 69/367 (19%)
Query 527 RELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNL-IIMRGARASPRTLNLSQLSFHRVD 585
+++ + + A F + + + +++ +RG T L Q+ +
Sbjct 618 KDIILKVGVPVAAATLLLFIIVGVFWKKRRDKNDIDKELRGLDLQTGTFTLRQI---KAA 674
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+G+G +VY+G L + +K L
Sbjct 675 TDNFDVTRKIGEGGFGSVYKGELSEGK-------------------------LIAVKQLS 709
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR----R 701
F ++S + H +L ++G CV G + I+V EY+E+ L L
Sbjct 710 AKSRQGNREFVNEIGMISALQHPNLVKLYGCCVEGNQLILVYEYLENNCLSRALFGKDES 769
Query 702 ERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
R + + + + +A L++L + +VH ++ N+LL + K+S
Sbjct 770 SRLKLDWSTRKKIFLGIAKGLTFLHEESRIKIVHRDIKASNVLLDK-------DLNAKIS 822
Query 759 DPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
D G+ + I ++APE G L+ D + FG LEI G++
Sbjct 823 DFGLAKLNDDGNTHISTRIAGTIGYMAPEYAMRGY--LTEKADVYSFGVVALEIVS-GKS 879
Query 814 PLQSRSPSEKEHFYQRQHRLPEPSC------PQLAT------------LTSQCLTYEPTQ 855
R + + + L E P LA+ + C PT
Sbjct 880 NTNFRPTEDFVYLLDWAYVLQERGSLLELVDPTLASDYSEEEAMLMLNVALMCTNASPTL 939
Query 856 RPSFRTI 862
RP+ +
Sbjct 940 RPTMSQV 946
>sp|Q9SR05|ANX1_ARATH Receptor-like protein kinase ANXUR1 OS=Arabidopsis
thaliana OX=3702 GN=ANX1 PE=1 SV=1
Length=850
Score = 254 bits (649), Expect = 1e-69, Method: Composition-based stats.
Identities = 74/296 (25%), Positives = 129/296 (44%), Gaps = 16/296 (5%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
+ + +G G FGKV D T VAVK + Q
Sbjct 502 CRRFSLPEIKHGTQNFDDSNVIGVGGFGKVYKGVIDGT-----TKVAVKKSNPN-SEQGL 555
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLA 998
+ ++ EI++L L H+H++ G C++ GE + LV +Y+ G+LR++L + +
Sbjct 556 NEFETEIELLSRLRHKHLVSLIGYCDEGGE--MCLVYDYMAFGTLREHLYNTKKPQLTWK 613
Query 999 QLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ L A G+ YLH IHRD+ N+L+D + + K+ DFGL+K P + +
Sbjct 614 RRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILVDENWVAKVSDFGLSKTGPNMNGGH 673
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGI 1114
V + PE + + SDV+SFGV L+E+L + + S P + + L
Sbjct 674 -VTTVVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLFEILCARPALNPSLPKEQVSLGDW 732
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
A L ++++ + +C + + C RPT +++ L+
Sbjct 733 AMNCKRKGNLEDIIDPNLKGKINAECLKKFADTAEKCLNDSGLERPTMGDVLWNLE 788
Score = 221 bits (562), Expect = 2e-58, Method: Composition-based stats.
Identities = 64/348 (18%), Positives = 108/348 (31%), Gaps = 53/348 (15%)
Query 579 LSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S + + + +G G VY+G +
Sbjct 505 FSLPEIKHGTQNFDDSNVIGVGGFGKVYKGVIDGT------------------------- 539
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+V +K +P+ F L+S++ H HL + G C G E +V +Y+ G L
Sbjct 540 TKVAVKKSNPNSEQGLNEFETEIELLSRLRHKHLVSLIGYCDEGGEMCLVYDYMAFGTLR 599
Query 697 VWLRR-ERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTS 752
L ++ + ++ +A A L YL ++H +V NIL+ +
Sbjct 600 EHLYNTKKPQLTWKRRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILVDE-------N 652
Query 753 PFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
K+SD G+ G +L PE L+ D + FG L E
Sbjct 653 WVAKVSDFGLSKTGPNMNGGHVTTVVKGSFGYLDPEYFR--RQQLTEKSDVYSFGVVLFE 710
Query 807 ICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLA-TLTSQCLTYEP-TQRPSF 859
I A P + S + +R+ L + P L + ++CL T
Sbjct 711 ILCARPALNPSLPKEQVSLGDWAMNCKRKGNLEDIIDPNLKGKINAECLKKFADTAEKCL 770
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
+ + + A DLG G
Sbjct 771 NDSGLERPTMGDVLWNLEFALQLQETADGTRHRTPNNGGSSEDLGRGG 818
>sp|Q98949|TYRO3_CHICK Tyrosine-protein kinase receptor TYRO3
OS=Gallus gallus OX=9031 GN=TYRO3 PE=1 SV=1
Length=873
Score = 254 bits (650), Expect = 1e-69, Method: Composition-based stats.
Identities = 89/283 (31%), Positives = 131/283 (46%), Gaps = 28/283 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
LG+G FG V +DG+ + VAVK LKAD + +E ++ H H+ K
Sbjct 511 LGKGEFGSVREALLK-LDDGSFQKVAVKMLKADIFTSTDIEEFLREAACMKEFDHPHVTK 569
Query 962 YKGCCEDQGEKS----LQLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEG 1010
G K +++ ++ G L +L ++ L LL F I G
Sbjct 570 LIGVSLRSRPKGRLPIPMVILPFMKHGDLHAFLLMSRIGENPFNLPLQTLLKFMIDIASG 629
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
M YL ++++IHRDLAARN +LD + V + DFGL+K + G +YYR PV W A
Sbjct 630 MEYLSSKNFIHRDLAARNCMLDENMNVSVADFGLSKKIYSG-DYYRQGCASKLPVKWLAL 688
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E L + + SDVW+FGVT++E++T + + L
Sbjct 689 ESLADNLYTTHSDVWAFGVTMWEIVTRGQ--------------TPYAGIENAEIYNYLIS 734
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
G RL +P +C +VY LM CW E RP+F L L+ +
Sbjct 735 GNRLKQPPECLEDVYDLMCRCWHPEPKLRPSFGVLRSQLEMIR 777
Score = 236 bits (601), Expect = 3e-63, Method: Composition-based stats.
Identities = 68/314 (22%), Positives = 123/314 (39%), Gaps = 51/314 (16%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
+L + +++ T LG+G +V E L++ D G
Sbjct 494 KLKDVLIQEQQFTLGRMLGKGEFGSVREALLKL---------------------DDGSFQ 532
Query 638 RVVLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN------IMVTEY 689
+V +K+L F A+ M + H H+ + GV +R +++ +
Sbjct 533 KVAVKMLKADIFTSTDIEEFLREAACMKEFDHPHVTKLIGVSLRSRPKGRLPIPMVILPF 592
Query 690 VEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
++HG L +L R ++P+ + +AS + YL +KN +H ++ RN +L
Sbjct 593 MKHGDLHAFLLMSRIGENPFNLPLQTLLKFMIDIASGMEYLSSKNFIHRDLAARNCMLDE 652
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKW 798
+ + ++D G+ S + + + WLA E L +T D W
Sbjct 653 -------NMNVSVADFGLSKKIYSGDYYRQGCASKLPVKWLALESLADNL--YTTHSDVW 703
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
FG T+ EI G+ P +E ++ +RL P + L +C EP R
Sbjct 704 AFGVTMWEIVTRGQTPYAGIENAEIYNYLISGNRLKQPPECLEDVYDLMCRCWHPEPKLR 763
Query 857 PSFRTILRDLTRLQ 870
PSF + L ++
Sbjct 764 PSFGVLRSQLEMIR 777
>sp|P08941|ROS1_CHICK Proto-oncogene tyrosine-protein kinase ROS
OS=Gallus gallus OX=9031 GN=ROS1 PE=1 SV=3
Length=2311
Score = 260 bits (665), Expect = 2e-69, Method: Composition-based stats.
Identities = 98/287 (34%), Positives = 136/287 (47%), Gaps = 33/287 (11%)
Query 903 LGEGHFGKVSLYC-YDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG G FG+V D DG+GE VAVK LK Q +S + +E ++ H HI+
Sbjct 1967 LGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMSKFDHPHIL 2026
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--------LLLFAQQICEGMA 1012
K G C + L++E + G L YL Q LL IC+G
Sbjct 2027 KLLGVCLLNEPQ--YLILELMEGGDLLSYLRGARKQKFQSPLLTLTDLLDICLDICKGCV 2084
Query 1013 YLHAQHYIHRDLAARNVLLDND------RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
YL +IHRDLAARN L+ R+VKIGDFGLA+ + + ++YYR R +G V
Sbjct 2085 YLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYK-NDYYRKRGEGLINVR 2143
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE L + F SDVW+FGV ++E LT L ++ + +
Sbjct 2144 WMAPESLIDGVFTNHSDVWAFGVLVWETLT--------------LGQQPYPGLSNIEVLH 2189
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ G RL P+ CP ++ LM CW + RPTF + L+ +
Sbjct 2190 HVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEIR 2236
Score = 258 bits (658), Expect = 1e-68, Method: Composition-based stats.
Identities = 73/315 (23%), Positives = 114/315 (36%), Gaps = 36/315 (11%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
S + ++ LG G VYEG L D E RV
Sbjct 1952 SLPAFPRDKLNLHKLLGSGAFGEVYEG------------------TALDILADGSGESRV 1993
Query 640 VLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+K L D F + A LMS+ H H+ + GVC+ ++ E +E G L +
Sbjct 1994 AVKTLKRGATDQEKSEFLKEAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSY 2053
Query 699 LRRERGH------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752
LR R + + + + + YLE +H ++ RN L++ S
Sbjct 2054 LRGARKQKFQSPLLTLTDLLDICLDICKGCVYLEKMRFIHRDLAARNCLVSEKQYGSC-S 2112
Query 753 PFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+K+ D G+ + +R + W+APE L G + D W FG + E
Sbjct 2113 RVVKIGDFGLARDIYKNDYYRKRGEGLINVRWMAPESLIDGV--FTNHSDVWAFGVLVWE 2170
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
G+ P S E H + RL P + L ++C +P RP+F I
Sbjct 2171 TLTLGQQPYPGLSNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQH 2230
Query 865 DLTRLQPHNLADVLT 879
L ++ L
Sbjct 2231 KLQEIRHSPLCFSYF 2245
>sp|Q9LRP3|Y3174_ARATH Probable receptor-like protein kinase At3g17420
OS=Arabidopsis thaliana OX=3702 GN=At3g17420 PE=1 SV=1
Length=467
Score = 244 bits (623), Expect = 2e-69, Method: Composition-based stats.
Identities = 61/303 (20%), Positives = 119/303 (39%), Gaps = 19/303 (6%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ K +G+G +G V VAVK L + G
Sbjct 135 HIGWGHWFTLRDLQLATNHFSKESIIGDGGYGVVYHGTL-----TNKTPVAVKKLLNNPG 189
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR-----DYLPR 992
Q ++ E++ + + H+++++ G C + + LV EY+ G+L D + +
Sbjct 190 -QADKDFRVEVEAIGHVRHKNLVRLLGYCVEGTHR--MLVYEYMNNGNLEQWLHGDMIHK 246
Query 993 HSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
+ + + +AYLH +HRD+ + N+L+D++ K+ DFGLAK +
Sbjct 247 GHLTWEARIKVLVGTAKALAYLHEAIEPKVVHRDIKSSNILMDDNFDAKLSDFGLAKLLG 306
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKF 1108
Y R + APE SDV+S+GV L E +T + P +
Sbjct 307 ADSNYVSTR--VMGTFGYVAPEYANSGLLNEKSDVYSYGVVLLEAITGRYPVDYARPKEE 364
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
+ ++ + + + E++++ + C + +A RP + +
Sbjct 365 VHMVEWLKLMVQQKQFEEVVDKELEIKPTTSELKRALLTALRCVDPDADKRPKMSQVARM 424
Query 1169 LKT 1171
L++
Sbjct 425 LES 427
Score = 222 bits (566), Expect = 7e-62, Method: Composition-based stats.
Identities = 69/342 (20%), Positives = 116/342 (34%), Gaps = 48/342 (14%)
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
+ L ++ ++ S +G G VY G L
Sbjct 140 HWFTLRDLQLATNHFSKESIIGDGGYGVVYHGTL-------------------------T 174
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+ V +K L + F + V H +L + G CV G ++V EY+ +G
Sbjct 175 NKTPVAVKKLLNNPGQADKDFRVEVEAIGHVRHKNLVRLLGYCVEGTHRMLVYEYMNNGN 234
Query 695 LDVWLRR---ERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLA 748
L+ WL +GH+ ++ V A AL+YL +VH ++ NIL+
Sbjct 235 LEQWLHGDMIHKGHLTWEARIKVLVGTAKALAYLHEAIEPKVVHRDIKSSNILMD----- 289
Query 749 EGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+ KLSD G+ + V ++APE G L+ D + +G
Sbjct 290 --DNFDAKLSDFGLAKLLGADSNYVSTRVMGTFGYVAPEYANSGL--LNEKSDVYSYGVV 345
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
LLE G P+ P E+ H + + + Q + + L +PT R +L
Sbjct 346 LLEAI-TGRYPVDYARPKEEVHMVEWLKLMVQQK--QFEEVVDKELEIKPTTSELKRALL 402
Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
L + P ++ R +
Sbjct 403 TALRCVDPDADKRPKMSQVARMLESDEYPVMPREERRRRRNQ 444
>sp|Q9ASQ5|CRCK3_ARATH Calmodulin-binding receptor-like cytoplasmic
kinase 3 OS=Arabidopsis thaliana OX=3702 GN=CRCK3 PE=2
SV=1
Length=510
Score = 245 bits (626), Expect = 2e-69, Method: Composition-based stats.
Identities = 77/283 (27%), Positives = 125/283 (44%), Gaps = 14/283 (5%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+GEG FG V D G++VA+K K + R+ +K E+D+L + H +++
Sbjct 229 HQIGEGGFGVVFKGVLD-----DGQVVAIKRAKKEHFENLRTEFKSEVDLLSKIGHRNLV 283
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA- 1016
K G + E+ ++ EYV G+LRD+L + Q L +C G+ YLH+
Sbjct 284 KLLGYVDKGDER--LIITEYVRNGTLRDHLDGARGTKLNFNQRLEIVIDVCHGLTYLHSY 341
Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+ IHRD+ + N+LL + K+ DFG A+ P + V + PE +K
Sbjct 342 AERQIIHRDIKSSNILLTDSMRAKVADFGFARGGPTDSNQTHILTQVKGTVGYLDPEYMK 401
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
Y SDV+SFG+ L E+LT + + A + R+ EL++ R
Sbjct 402 TYHLTAKSDVYSFGILLVEILTGRRPVEAKRLPDERITVRWAFDKYNEGRVFELVDPNAR 461
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
+K +++ L C RP E + L + Y
Sbjct 462 ERVDEKILRKMFSLAFQCAAPTKKERPDMEAVGKQLWAIRSSY 504
Score = 216 bits (549), Expect = 3e-59, Method: Composition-based stats.
Identities = 69/343 (20%), Positives = 124/343 (36%), Gaps = 66/343 (19%)
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
R +R P L +SQ++ +G+G V++G L
Sbjct 204 RPSRLGPLNLTMSQINT---ATGNFADSHQIGEGGFGVVFKGVL---------------- 244
Query 625 DPLVPGRDRGQELRVVLKVLDPSH-HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
D GQ V +K H ++ F L+S++ H +L + G +G E
Sbjct 245 -------DDGQ--VVAIKRAKKEHFENLRTEFKSEVDLLSKIGHRNLVKLLGYVDKGDER 295
Query 684 IMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRN 739
+++TEYV +G L L RG + ++ + + L+YL + + ++H ++ N
Sbjct 296 LIITEYVRNGTLRDHLDGARGTKLNFNQRLEIVIDVCHGLTYLHSYAERQIIHRDIKSSN 355
Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-------ERIPWLAPECLPGGANSLS 792
ILL S K++D G G + + + +L PE + L+
Sbjct 356 ILLT-------DSMRAKVADFGFARGGPTDSNQTHILTQVKGTVGYLDPEYMKT--YHLT 406
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-----------------RQHRLPE 835
D + FG L+EI R P E+ + R+ E
Sbjct 407 AKSDVYSFGILLVEILTGRRPVEAKRLPDERITVRWAFDKYNEGRVFELVDPNARERVDE 466
Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
++ +L QC +RP + + L ++ L +
Sbjct 467 KILRKMFSLAFQCAAPTKKERPDMEAVGKQLWAIRSSYLRRSM 509
>sp|O22042|M3K3_ARATH Mitogen-activated protein kinase kinase
kinase 3 OS=Arabidopsis thaliana OX=3702 GN=ANP3 PE=1 SV=1
Length=651
Score = 249 bits (636), Expect = 2e-69, Method: Composition-based stats.
Identities = 69/279 (25%), Positives = 128/279 (46%), Gaps = 28/279 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-------KADCGPQHRSGWKQEID 949
+K +G G FG+V + N +GE++A+K + + H ++E+
Sbjct 68 WRKGELIGCGAFGRVYMGM----NLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQ 123
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQIC 1008
+L+ L H +I++Y G + SL ++ME+VP GS+ L + S ++++ +Q+
Sbjct 124 LLKNLSHPNIVRYLGTVRESD--SLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLL 181
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
G+ YLH +HRD+ N+L+DN +++ DFG +K V E + +P +W
Sbjct 182 LGLEYLHNNGIMHRDIKGANILVDNKGCIRLADFGASKKVVELATVNGAKSMKGTP-YWM 240
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
APE + + +++D+WS G T+ E+ T +F ++ I + +
Sbjct 241 APEVILQTGHSFSADIWSVGCTVIEMATGKPPWSEQYQQFAAVLHIGRTKA--------- 291
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P P+ E + C E S R + L+
Sbjct 292 ----HPPIPEDLSPEAKDFLMKCLHKEPSLRLSATELLQ 326
Score = 199 bits (507), Expect = 2e-52, Method: Composition-based stats.
Identities = 63/349 (18%), Positives = 111/349 (32%), Gaps = 37/349 (11%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
S++ R S L + +G G VY G G
Sbjct 37 NSSIRSSRIGLFSKPPPGLPAPRKEEAPSIRWRKGELIGCGAFGRVYMGMNLDSGELLAI 96
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
+ + + +G E L+ +SH ++ G
Sbjct 97 KQVLIAPSSASKEKTQGH----------------IRELEEEVQLLKNLSHPNIVRYLGTV 140
Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737
++ E+V G + L + G P ++ +QL L YL N ++H ++ G
Sbjct 141 RESDSLNILMEFVPGGSISSLL-EKFGSFPEPVIIMYTKQLLLGLEYLHNNGIMHRDIKG 199
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANSL 791
NIL+ G I+L+D G + + W+APE + +S
Sbjct 200 ANILVDNKG-------CIRLADFGASKKVVELATVNGAKSMKGTPYWMAPEVILQTGHSF 252
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR----LPEPSCPQLATLTSQ 847
S D W G T++E+ G+ P + + + + +PE P+ +
Sbjct 253 S--ADIWSVGCTVIEMA-TGKPPWSEQYQQFAAVLHIGRTKAHPPIPEDLSPEAKDFLMK 309
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896
CL EP+ R S +L+ N + +P
Sbjct 310 CLHKEPSLRLSATELLQHPFVTGKRQEPYPAYRNSLTECGNPITTQGMN 358
>sp|Q9C6K9|LRL11_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE
PROTEIN KINASE-like 1.1 OS=Arabidopsis thaliana
OX=3702 GN=LRK10L-1.1 PE=2 SV=1
Length=629
Score = 249 bits (635), Expect = 2e-69, Method: Composition-based stats.
Identities = 80/285 (28%), Positives = 131/285 (46%), Gaps = 19/285 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V G VAVK L + + + EI+IL L+H++++
Sbjct 297 LGDGGFGTVYYG-----KVRDGREVAVKRL-YEHNYRRLEQFMNEIEILTRLHHKNLVSL 350
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQLLLFAQQICEGMAYLHA 1016
G C + + L LV E++P G++ D+L + + + L A + +AYLHA
Sbjct 351 YG-CTSRRSRELLLVYEFIPNGTVADHLYGENTPHQGFLTWSMRLSIAIETASALAYLHA 409
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ N+LLD + VK+ DFGL++ +P + G + PE + Y
Sbjct 410 SDIIHRDVKTTNILLDRNFGVKVADFGLSRLLPSDVTHVSTAPQG--TPGYVDPEYHRCY 467
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
SDV+SFGV L EL++ + S + L +A ++ EL+++
Sbjct 468 HLTDKSDVYSFGVVLVELISSKPAVDISRCKSEINLSSLAINKIQNHATHELIDQNLGYA 527
Query 1136 RPD---KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
+ K V L C + + + RPT E ++ LK + + Q
Sbjct 528 TNEGVRKMTTMVAELAFQCLQQDNTMRPTMEQVVHELKGIQNEEQ 572
Score = 217 bits (553), Expect = 1e-58, Method: Composition-based stats.
Identities = 65/353 (18%), Positives = 123/353 (35%), Gaps = 66/353 (19%)
Query 574 LNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
+ S+ + ++ LG G VY G++R
Sbjct 274 FKIPIFSYKELQAATDNFSKDRLLGDGGFGTVYYGKVRDGR------------------- 314
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV-CVRGPENIMVTEYV 690
V +K L ++ F +++++ H +L ++G R E ++V E++
Sbjct 315 ------EVAVKRLYEHNYRRLEQFMNEIEILTRLHHKNLVSLYGCTSRRSRELLLVYEFI 368
Query 691 EHGPLDVWLRRE----RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
+G + L E +G + + ++ +A + ASAL+YL +++H +V NILL R
Sbjct 369 PNGTVADHLYGENTPHQGFLTWSMRLSIAIETASALAYLHASDIIHRDVKTTNILLDR-- 426
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFG 801
+ +K++D G+ S V ++ PE L+ D + FG
Sbjct 427 -----NFGVKVADFGLSRLLPSDVTHVSTAPQGTPGYVDPEY--HRCYHLTDKSDVYSFG 479
Query 802 ATLLEICFDGEAPLQSRSPSEK--------------------EHFYQRQHRLPEPSCPQL 841
L+E+ A SR SE ++ + +
Sbjct 480 VVLVELISSKPAVDISRCKSEINLSSLAINKIQNHATHELIDQNLGYATNEGVRKMTTMV 539
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894
A L QCL + T RP+ ++ +L +Q +
Sbjct 540 AELAFQCLQQDNTMRPTMEQVVHELKGIQNEEQKCPTYDYREETIIPHPSPPD 592
>sp|O76997|TRK1_LYMST Putative neurotrophin receptor LTRK 1 OS=Lymnaea
stagnalis OX=6523 PE=2 SV=1
Length=794
Score = 253 bits (645), Expect = 2e-69, Method: Composition-based stats.
Identities = 88/289 (30%), Positives = 136/289 (47%), Gaps = 37/289 (13%)
Query 903 LGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG FG+V L C +VAVK LK C + +++E ++L T+ H +I+
Sbjct 510 IGEGAFGRVFLGTCAHLIQKNEFAIVAVKTLKGSCSDSLKRDFEREAEMLATIEHANIVT 569
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------------------IGLAQLLLF 1003
+ G C + + ++ E++ G L YL H + QL+
Sbjct 570 FYGVCTESDQ--WMMIFEFMENGDLNKYLRMHGPDAAFLKDRDSMDSDEGQLTREQLMKI 627
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
QI M YL QH++HRDLA RN L+ D +VK+GDFG+++ V +YYRV
Sbjct 628 VLQIASAMEYLALQHFVHRDLATRNCLVGCDLVVKLGDFGMSRDVY-TTDYYRVEGTAML 686
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
PV W PE + F SDVWSFGVTL+E+ T+ + +
Sbjct 687 PVRWMPPESIIYRTFTTESDVWSFGVTLWEVFTYGKQ--------------PWFEYSNSE 732
Query 1124 LTELLERGERLPRPDK-CPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ E ++ L RP + C VY +M+ CW+ R T +++ +L+
Sbjct 733 VIEHIKNSRTLKRPPRTCTDGVYRVMQGCWKPNPQDRLTMKDIAELLRE 781
Score = 244 bits (622), Expect = 2e-66, Method: Composition-based stats.
Identities = 64/327 (20%), Positives = 121/327 (37%), Gaps = 54/327 (17%)
Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
++ + +++ V + I + +G+G V+ G
Sbjct 477 LVDNPNYNLTKKKHVATTCPKTVRLQTILLMRVIGEGAFGRVFLGTCAHL---------- 526
Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCVRG 680
+ + V +K L S D + F A +++ + H ++ +GVC
Sbjct 527 ---------IQKNEFAIVAVKTLKGSCSDSLKRDFEREAEMLATIEHANIVTFYGVCTES 577
Query 681 PENIMVTEYVEHGPLDVWLR----------------RERGHVPMAWKMVVAQQLASALSY 724
+ +M+ E++E+G L+ +LR + G + M + Q+ASA+ Y
Sbjct 578 DQWMMIFEFMENGDLNKYLRMHGPDAAFLKDRDSMDSDEGQLTREQLMKIVLQIASAMEY 637
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPW 778
L ++ VH ++ RN L+ G +KL D G+ + + + + W
Sbjct 638 LALQHFVHRDLATRNCLV-------GCDLVVKLGDFGMSRDVYTTDYYRVEGTAMLPVRW 690
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---HRLPE 835
+ PE + + +T D W FG TL E+ G+ P S SE + R P
Sbjct 691 MPPESII--YRTFTTESDVWSFGVTLWEVFTYGKQPWFEYSNSEVIEHIKNSRTLKRPPR 748
Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTI 862
+ + C P R + + I
Sbjct 749 TCTDGVYRVMQGCWKPNPQDRLTMKDI 775
>sp|O64781|Y1639_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61390 OS=Arabidopsis thaliana OX=3702
GN=At1g61390 PE=3 SV=1
Length=831
Score = 253 bits (647), Expect = 2e-69, Method: Composition-based stats.
Identities = 81/345 (23%), Positives = 132/345 (38%), Gaps = 18/345 (5%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
Y Q + ++ + LG+G F
Sbjct 472 WRYRTKQNEPNPMFIHSSQDAWAKDMEPQDVSGVNLFDMHTIRTATNNFSSSNKLGQGGF 531
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968
G V G+ +AVK L + G Q + EI ++ L H+++++ GCC
Sbjct 532 GPVYKG-----KLVDGKEIAVKRLSSSSG-QGTDEFMNEIRLISKLQHKNLVRLLGCCIK 585
Query 969 QGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQ---HYIH 1021
EK L+ EY+ SL +L + I + Q + G+ YLH IH
Sbjct 586 GEEK--LLIYEYLVNKSLDVFLFDSTLKFEIDWQKRFNIIQGVARGLLYLHRDSRLRVIH 643
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RDL N+LLD + KI DFGLA+ + +G +Y + + APE F
Sbjct 644 RDLKVSNILLDEKMIPKISDFGLAR-MSQGTQYQDNTRRVVGTLGYMAPEYAWTGVFSEK 702
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
SD++SFGV L E++ S+ + L+ A + +LL++
Sbjct 703 SDIYSFGVLLLEIIIGEKISRF-SEEGKTLLAYAWESWCETKGVDLLDQALADSSHPAEV 761
Query 1142 CEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
+ C + + + RP L+ +L T+ E + P F+V
Sbjct 762 GRCVQIGLLCVQHQPADRPNTLELMSMLTTISELPSPKQP-TFTV 805
Score = 233 bits (595), Expect = 9e-63, Method: Composition-based stats.
Identities = 57/247 (23%), Positives = 96/247 (39%), Gaps = 45/247 (18%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
+NL + R + + LGQG VY+G+L
Sbjct 505 VNLFDMHTIRTATNNFSSSNKLGQGGFGPVYKGKLVDGK--------------------- 543
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ +K L S F L+S++ H +L + G C++G E +++ EY+ +
Sbjct 544 ----EIAVKRLSSSSGQGTDEFMNEIRLISKLQHKNLVRLLGCCIKGEEKLLIYEYLVNK 599
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748
LDV+L + W + + Q +A L YL ++H ++ NILL +
Sbjct 600 SLDVFLFDSTLKFEIDWQKRFNIIQGVARGLLYLHRDSRLRVIHRDLKVSNILLDEKMIP 659
Query 749 EGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGA 802
K+SD G+ + + + V + ++APE G S D + FG
Sbjct 660 -------KISDFGLARMSQGTQYQDNTRRVVGTLGYMAPEYAWTGV--FSEKSDIYSFGV 710
Query 803 TLLEICF 809
LLEI
Sbjct 711 LLLEIII 717
>sp|O65472|CRK12_ARATH Putative cysteine-rich receptor-like protein
kinase 12 OS=Arabidopsis thaliana OX=3702 GN=CRK12 PE=3
SV=3
Length=659
Score = 249 bits (636), Expect = 2e-69, Method: Composition-based stats.
Identities = 63/324 (19%), Positives = 115/324 (35%), Gaps = 65/324 (20%)
Query 573 TLNLSQLSFH--RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
TL+ QL F V + + + LGQG VY+G L
Sbjct 318 TLHFQQLDFKTIEVATENFAKTNKLGQGGFGEVYKGTLVNG------------------- 358
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
V +K L + A F L++++ H +L + G C+ E I+V E+V
Sbjct 359 ------TEVAVKRLSKTSEQGAQEFKNEVVLVAKLQHRNLVKLLGYCLEPEEKILVYEFV 412
Query 691 EHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745
+ LD +L ++G + + + + + YL + ++H ++ NILL
Sbjct 413 PNKSLDYFLFDPTKQGQLDWTKRYNIIGGITRGILYLHQDSRLTIIHRDLKASNILLD-- 470
Query 746 GLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
K++D G+ + + ++ PE + G S D +
Sbjct 471 -----ADMIPKIADFGMARISGIDQSVANTKRIAGTFGYMPPEYVIHG--QFSMKSDVYS 523
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------------QL 841
FG +LEI + ++ ++ E+ RL P +
Sbjct 524 FGVLILEIICGKKNRSFYQADTKAENLVTYVWRLWTNGSPLELVDLTISENCQTEEVIRC 583
Query 842 ATLTSQCLTYEPTQRPSFRTILRD 865
+ C+ +P RP+ TI+
Sbjct 584 IHIALLCVQEDPKDRPNLSTIMMM 607
Score = 247 bits (631), Expect = 1e-68, Method: Composition-based stats.
Identities = 79/304 (26%), Positives = 118/304 (39%), Gaps = 26/304 (9%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH 940
+ K LG+G FG+V G VAVK L Q
Sbjct 320 HFQQLDFKTIEVATENFAKTNKLGQGGFGEVYKGTL-----VNGTEVAVKRLSK-TSEQG 373
Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIG 996
+K E+ ++ L H +++K G C + EK LV E+VP SL +L + +
Sbjct 374 AQEFKNEVVLVAKLQHRNLVKLLGYCLEPEEK--ILVYEFVPNKSLDYFLFDPTKQGQLD 431
Query 997 LAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ I G+ YLH IHRDL A N+LLD D + KI DFG+A+
Sbjct 432 WTKRYNIIGGITRGILYLHQDSRLTIIHRDLKASNILLDADMIPKIADFGMARISGIDQS 491
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC--DSSQSPPTKFLEL 1111
+ + PE + +F SDV+SFGV + E++ S TK L
Sbjct 492 VANTKRIA-GTFGYMPPEYVIHGQFSMKSDVYSFGVLILEIICGKKNRSFYQADTKAENL 550
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCE----VYHLMKNCWETEASFRPTFENLIP 1167
+ T EL++ L + C E H+ C + + RP ++
Sbjct 551 VTYVWRLWTNGSPLELVD----LTISENCQTEEVIRCIHIALLCVQEDPKDRPNLSTIMM 606
Query 1168 ILKT 1171
+L
Sbjct 607 MLTN 610
>sp|Q9LSE1|CDG1_ARATH Serine/threonine-protein kinase CDG1 OS=Arabidopsis
thaliana OX=3702 GN=CDG1 PE=1 SV=1
Length=432
Score = 243 bits (619), Expect = 2e-69, Method: Composition-based stats.
Identities = 79/288 (27%), Positives = 131/288 (45%), Gaps = 27/288 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V TG+ +AVK L G Q + E+ +L L+H +++
Sbjct 80 IGRGGFGTVYKGRL-----STGQNIAVKMLDQ-SGIQGDKEFLVEVLMLSLLHHRNLVHL 133
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
G C + ++ +V EY+PLGS+ D+L + ++ + A +G+A+LH +
Sbjct 134 FGYCAEGDQR--LVVYEYMPLGSVEDHLYDLSEGQEALDWKTRMKIALGAAKGLAFLHNE 191
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
I+RDL N+LLD+D K+ DFGLAK P + V + APE
Sbjct 192 AQPPVIYRDLKTSNILLDHDYKPKLSDFGLAKFGPSDDMSH-VSTRVMGTHGYCAPEYAN 250
Query 1075 EYKFYYASDVWSFGVTLYELLTHC----DSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
K SD++SFGV L EL++ SS+ + L+ A+ R+ ++++
Sbjct 251 TGKLTLKSDIYSFGVVLLELISGRKALMPSSECVGNQSRYLVHWARPLFLNGRIRQIVDP 310
Query 1131 GERLPRPDKCPCEV----YHLMKNCWETEASFRPTFENLIPILKTVHE 1174
RL R + + C EA+ RP+ ++ LK + +
Sbjct 311 --RLARKGGFSNILLYRGIEVAFLCLAEEANARPSISQVVECLKYIID 356
Score = 222 bits (566), Expect = 3e-62, Method: Composition-based stats.
Identities = 69/351 (20%), Positives = 125/351 (36%), Gaps = 71/351 (20%)
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615
+S ++ +R + + +L+ + S +G+G VY+GRL +
Sbjct 44 SSSSQTVVQDSSRYRCQIFSYRELA---IATNSFRNESLIGRGGFGTVYKGRLSTGQN-- 98
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675
+ +K+LD S F ++S + H +L + G
Sbjct 99 -----------------------IAVKMLDQSGIQGDKEFLVEVLMLSLLHHRNLVHLFG 135
Query 676 VCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYLENK---N 729
C G + ++V EY+ G ++ L G + W +M +A A L++L N+
Sbjct 136 YCAEGDQRLVVYEYMPLGSVEDHLYDLSEGQEALDWKTRMKIALGAAKGLAFLHNEAQPP 195
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPEC 783
+++ ++ NILL KLSD G+ S + + + APE
Sbjct 196 VIYRDLKTSNILLDHDYKP-------KLSDFGLAKFGPSDDMSHVSTRVMGTHGYCAPEY 248
Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGE--APLQSRSPSEKEHFYQR------QHRLPE 835
G L+ D + FG LLE+ + P ++ + R+ +
Sbjct 249 ANTG--KLTLKSDIYSFGVVLLELISGRKALMPSSECVGNQSRYLVHWARPLFLNGRIRQ 306
Query 836 PSCPQLA--------------TLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
P+LA + CL E RPS ++ L + H
Sbjct 307 IVDPRLARKGGFSNILLYRGIEVAFLCLAEEANARPSISQVVECLKYIIDH 357
>sp|P08069|IGF1R_HUMAN Insulin-like growth factor 1 receptor OS=Homo
sapiens OX=9606 GN=IGF1R PE=1 SV=1
Length=1367
Score = 259 bits (661), Expect = 2e-69, Method: Composition-based stats.
Identities = 92/312 (29%), Positives = 144/312 (46%), Gaps = 29/312 (9%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALK 933
D D + + R+LG+G FG V E VA+K +
Sbjct 977 NPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVN 1036
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR- 992
+ R + E +++ H+++ G QG+ +L ++ME + G L+ YL
Sbjct 1037 EAASMRERIEFLNEASVMKEFNCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSL 1094
Query 993 ----------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
L++++ A +I +GMAYL+A ++HRDLAARN ++ D VKIGDF
Sbjct 1095 RPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDF 1154
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
G+ + + E +YYR G PV W +PE LK+ F SDVWSFGV L+E+ T
Sbjct 1155 GMTRDIYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIAT------ 1207
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
L ++ ++ + G L +PD CP ++ LM+ CW+ RP+F
Sbjct 1208 --------LAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSF 1259
Query 1163 ENLIPILKTVHE 1174
+I +K E
Sbjct 1260 LEIISSIKEEME 1271
Score = 252 bits (644), Expect = 3e-67, Method: Composition-based stats.
Identities = 99/488 (20%), Positives = 172/488 (35%), Gaps = 87/488 (18%)
Query 425 RLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLI 484
+L +S+++ P D I GP+ RPE+ ++L +P LI
Sbjct 812 KLGCSASNFVFARTMPA----EGADDIPGPVTWE-----PRPENSIFLKWPEPENPNGLI 862
Query 485 LTVAQR-SQAPDGMQSL----RLRKFPIEQQD-----------GAFVLEGWGR------- 521
L + + + RK+ + + A L G G
Sbjct 863 LMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFF 922
Query 522 ------SFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLN 575
+ + L AL +L + + + + A +P +
Sbjct 923 YVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFS 982
Query 576 LSQL---SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
+ + V +++IT LGQG+ VYEG + +P
Sbjct 983 AADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEP---------------- 1026
Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
E RV +K ++ + + F AS+M + + H+ + GV +G +++ E +
Sbjct 1027 ---ETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMT 1083
Query 692 HGPLDVWLRRERGHV---------PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
G L +LR R + ++ + +A ++A ++YL VH ++ RN ++
Sbjct 1084 RGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV 1143
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMD 796
A +K+ D G+ + + + W++PE L G +T D
Sbjct 1144 AE-------DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTYSD 1194
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854
W FG L EI E P Q S + F L P+ L L C Y P
Sbjct 1195 VWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPK 1254
Query 855 QRPSFRTI 862
RPSF I
Sbjct 1255 MRPSFLEI 1262
>sp|Q54VC0|Y9865_DICDI Probable serine/threonine-protein kinase
DDB_G0280461 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0280461
PE=3 SV=1
Length=418
Score = 242 bits (617), Expect = 2e-69, Method: Composition-based stats.
Identities = 76/306 (25%), Positives = 129/306 (42%), Gaps = 34/306 (11%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHR 941
D + + + +G F KV Y G V VK +K D +
Sbjct 1 MKIKDFNIECDNLKIEENEFSKGSFAKVYKGSY------YGNPVCVKVIKKDTLIDKESW 54
Query 942 SGWKQEIDILRTL---YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI--G 996
K+EI IL+ L H++II++ G + + L LV E + G L + L H
Sbjct 55 VFLKREIGILKNLLNQGHKNIIRFIGI--GEKDSLLFLVTELINGGDLGNILLDHKFHIP 112
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
+ + A+ I EGM YLH++ +HRDL + N+LL + +KI DFG AK + +
Sbjct 113 WSLRVKIAKDIAEGMEYLHSKQIMHRDLKSNNLLLGRNWTIKICDFGFAKEITIQNP--- 169
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
+ + +PE + ++ Y++D++SFG+ L EL+T + P ++
Sbjct 170 LSMTICGTDEFMSPEVILGIQYSYSADIYSFGMVLLELITRSKLDERLPQNNFDIDY--- 226
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
+ P +CP E L C + + RP+F +++ L + K
Sbjct 227 -------------EELQNKIPSECPREFLELSMKCCNYDPNDRPSFTDIVQTLDQLAIKL 273
Query 1177 QGQAPS 1182
+ P
Sbjct 274 VKETPD 279
Score = 199 bits (506), Expect = 2e-54, Method: Composition-based stats.
Identities = 59/331 (18%), Positives = 122/331 (37%), Gaps = 51/331 (15%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
++++ E + +G+ VY+G V +K
Sbjct 14 KIEENEFS------KGSFAKVYKGSYYGN--------------------------PVCVK 41
Query 643 VLDPS---HHDIALAFYETASLMSQV---SHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V+ + + ++ + H ++ G+ + +VTE + G L
Sbjct 42 VIKKDTLIDKESWVFLKREIGILKNLLNQGHKNIIRFIGIGEKDSLLFLVTELINGGDLG 101
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
L + H+P + ++ +A+ +A + YL +K ++H ++ N+LL R + IK
Sbjct 102 NILLDHKFHIPWSLRVKIAKDIAEGMEYLHSKQIMHRDLKSNNLLLGR-------NWTIK 154
Query 757 LSDPGVGLGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
+ D G + I +++PE + G S S D + FG LLE+ +
Sbjct 155 ICDFGFAKEITIQNPLSMTICGTDEFMSPEVILGIQYSYS--ADIYSFGMVLLELITRSK 212
Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
+ + + + Q+++P + L+ +C Y+P RPSF I++ L +L
Sbjct 213 LDERLPQNNFDIDYEELQNKIPSECPREFLELSMKCCNYDPNDRPSFTDIVQTLDQLAIK 272
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
+ + S + H
Sbjct 273 LVKETPDGPYPSTPIVVSNPHFDDQSINDWC 303
>sp|P00535|ERBB_AVIER Tyrosine-protein kinase transforming protein
erbB OS=Avian erythroblastosis virus (strain ES4) OX=79685
GN=V-ERBB PE=3 SV=1
Length=604
Score = 248 bits (632), Expect = 2e-69, Method: Composition-based stats.
Identities = 90/272 (33%), Positives = 134/272 (49%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG + + P + VA+K L+ P+ E ++ ++ + H+ +
Sbjct 138 LGSGAFGTIYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRL 197
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C +QL+ + +P G L DY+ H IG LL + QI +GM YL + +
Sbjct 198 LGICLTST---VQLITQLMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLV 254
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ + VKI DFGLAK + + Y E G P+ W A E + + +
Sbjct 255 HRDLAARNVLVKTPQHVKITDFGLAKLLGADEKEYHA-EGGKVPIKWMALESILHRIYTH 313
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + ++ +LE+GERLP+P C
Sbjct 314 QSDVWSYGVTVWELMTFGSK--------------PYDGIPASEISSVLEKGERLPQPPIC 359
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW +A RP F LI +
Sbjct 360 TIDVYMIMVKCWMIDADSRPKFRELIAEFSKM 391
Score = 223 bits (569), Expect = 6e-61, Method: Composition-based stats.
Identities = 67/345 (19%), Positives = 136/345 (39%), Gaps = 39/345 (11%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P +Q + + E ++ LG G +Y+G EG
Sbjct 113 TPSGEAPNQAHLRILKETEFKKVKVLGSGAFGTIYKGLWIPEGEKV-------------- 158
Query 630 GRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ V +K L + + A +M+ V + H+ + G+C+ ++T+
Sbjct 159 ------KIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQ-LITQ 211
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ +G L ++R + ++ + + Q+A ++YLE + LVH ++ RN+L+
Sbjct 212 LMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLVHRDLAARNVLV------ 265
Query 749 EGTSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGA 802
T +K++D G+ LGA +E E I W+A E + + D W +G
Sbjct 266 -KTPQHVKITDFGLAKLLGADEKEYHAEGGKVPIKWMALESILHRI--YTHQSDVWSYGV 322
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860
T+ E+ G P SE ++ RLP+P + + +C + RP FR
Sbjct 323 TVWELMTFGSKPYDGIPASEISSVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFR 382
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
++ + +++ ++ + K Y + +
Sbjct 383 ELIAEFSKMARDPPRYLVIQGDERMHLPSPTDSKFYRTLMEEEDM 427
>sp|Q8LEB6|Y5185_ARATH Probable receptor-like protein kinase At5g18500
OS=Arabidopsis thaliana OX=3702 GN=At5g18500 PE=2 SV=1
Length=484
Score = 244 bits (623), Expect = 3e-69, Method: Composition-based stats.
Identities = 65/307 (21%), Positives = 115/307 (37%), Gaps = 19/307 (6%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933
+ +G+G +G V N G VAVK L
Sbjct 143 PEFSHLGWGHWFTLRDLQMATNQFSRDNIIGDGGYGVVYRG-----NLVNGTPVAVKKLL 197
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991
+ G Q ++ E++ + + H+++++ G C + ++ LV EYV G+L +L
Sbjct 198 NNLG-QADKDFRVEVEAIGHVRHKNLVRLLGYCMEGTQR--MLVYEYVNNGNLEQWLRGD 254
Query 992 ---RHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+ + + +AYLH +HRD+ + N+L+D+ KI DFGLA
Sbjct 255 NQNHEYLTWEARVKILIGTAKALAYLHEAIEPKVVHRDIKSSNILIDDKFNSKISDFGLA 314
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSP 1104
K + + R + APE SDV+SFGV L E +T +
Sbjct 315 KLLGADKSFITTR--VMGTFGYVAPEYANSGLLNEKSDVYSFGVVLLEAITGRYPVDYAR 372
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
P + L+ + + R E+++ C + + RP
Sbjct 373 PPPEVHLVEWLKMMVQQRRSEEVVDPNLETKPSTSALKRTLLTALRCVDPMSEKRPRMSQ 432
Query 1165 LIPILKT 1171
+ +L++
Sbjct 433 VARMLES 439
Score = 217 bits (553), Expect = 6e-60, Method: Composition-based stats.
Identities = 64/344 (19%), Positives = 117/344 (34%), Gaps = 48/344 (14%)
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
+ L ++ + ++ + +G G VY G L
Sbjct 152 HWFTLRDLQMATNQFSRDNIIGDGGYGVVYRGNLVNG----------------------- 188
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
V +K L + F + V H +L + G C+ G + ++V EYV +G
Sbjct 189 --TPVAVKKLLNNLGQADKDFRVEVEAIGHVRHKNLVRLLGYCMEGTQRMLVYEYVNNGN 246
Query 695 LDVWLRRERGH---VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLA 748
L+ WLR + + + ++ + A AL+YL +VH ++ NIL+ +
Sbjct 247 LEQWLRGDNQNHEYLTWEARVKILIGTAKALAYLHEAIEPKVVHRDIKSSNILIDDKFNS 306
Query 749 EGTSPFIKLSDPGVGLGALSREE-----RVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
K+SD G+ + + + ++APE G L+ D + FG
Sbjct 307 -------KISDFGLAKLLGADKSFITTRVMGTFGYVAPEYANSGL--LNEKSDVYSFGVV 357
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
LLE +R P E + + + ++ L +P+ RT+L
Sbjct 358 LLEAITGRYPVDYARPPPEVHLVEWLKMMVQQRRSEEVVDP---NLETKPSTSALKRTLL 414
Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
L + P + R ++ R G
Sbjct 415 TALRCVDPMSEKRPRMSQVARMLESEEYPIAREDRRRRRSQNGT 458
>sp|O64784|Y1136_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61360 OS=Arabidopsis thaliana OX=3702
GN=At1g61360 PE=2 SV=1
Length=821
Score = 253 bits (645), Expect = 3e-69, Method: Composition-based stats.
Identities = 85/354 (24%), Positives = 133/354 (38%), Gaps = 19/354 (5%)
Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897
C L + C Y Q S ++ +L +
Sbjct 439 CLILVLVACGCWRYRVKQNGSSLVSKDNVEGAWKSDLQSQDVSGLNFFEIHDLQTATNNF 498
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+ LG+G FG V G+ +AVK L Q + EI ++ L H
Sbjct 499 SVLNKLGQGGFGTVYKGKLQ-----DGKEIAVKRL-TSSSVQGTEEFMNEIKLISKLQHR 552
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSL----RDYLPRHSIGLAQLLLFAQQICEGMAY 1013
++++ GCC D EK LV EY+ SL D + I A Q I G+ Y
Sbjct 553 NLLRLLGCCIDGEEK--LLVYEYMVNKSLDIFIFDLKKKLEIDWATRFNIIQGIARGLLY 610
Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
LH +HRDL N+LLD KI DFGLA+ G+++ + + +P
Sbjct 611 LHRDSFLRVVHRDLKVSNILLDEKMNPKISDFGLARLF-HGNQHQDSTGSVVGTLGYMSP 669
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E F SD++SFGV + E++T + SS S L+ A + LL+
Sbjct 670 EYAWTGTFSEKSDIYSFGVLMLEIITGKEISSFSYGKDNKNLLSYAWDSWSENGGVNLLD 729
Query 1130 RGERLPRPDKCPC--EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
+ H+ C + +A RP + ++ +L + + + P
Sbjct 730 QDLDDSDSVNSVEAGRCVHIGLLCVQHQAIDRPNIKQVMSMLTSTTDLPKPTQP 783
Score = 237 bits (605), Expect = 4e-64, Method: Composition-based stats.
Identities = 57/250 (23%), Positives = 98/250 (39%), Gaps = 45/250 (18%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
LN ++ + + L+ LGQG VY+G+L+
Sbjct 483 LNFFEIHDLQTATNNFSVLNKLGQGGFGTVYKGKLQDGK--------------------- 521
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ +K L S F L+S++ H +L + G C+ G E ++V EY+ +
Sbjct 522 ----EIAVKRLTSSSVQGTEEFMNEIKLISKLQHRNLLRLLGCCIDGEEKLLVYEYMVNK 577
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748
LD+++ + + + W + + Q +A L YL +VH ++ NILL
Sbjct 578 SLDIFIFDLKKKLEIDWATRFNIIQGIARGLLYLHRDSFLRVVHRDLKVSNILLDEK--- 634
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
K+SD G+ S V + +++PE G + S D + FG
Sbjct 635 ----MNPKISDFGLARLFHGNQHQDSTGSVVGTLGYMSPEYAWTG--TFSEKSDIYSFGV 688
Query 803 TLLEICFDGE 812
+LEI E
Sbjct 689 LMLEIITGKE 698
>sp|O81832|Y4729_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At4g27290 OS=Arabidopsis thaliana OX=3702
GN=At4g27290 PE=3 SV=4
Length=783
Score = 252 bits (643), Expect = 3e-69, Method: Composition-based stats.
Identities = 80/275 (29%), Positives = 118/275 (43%), Gaps = 18/275 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG+G FG V G+ VAVK L Q +K EI ++ L H +++
Sbjct 469 NKLGQGGFGPVYKGTL-----ACGQEVAVKRLSR-TSRQGVEEFKNEIKLIAKLQHRNLV 522
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016
K G C D+ E+ L+ EY P SL ++ R + + + + I GM YLH
Sbjct 523 KILGYCVDEEER--MLIYEYQPNKSLDSFIFDKERRRELDWPKRVEIIKGIARGMLYLHE 580
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRDL A NVLLD+D KI DFGLA+ + G E + +PE
Sbjct 581 DSRLRIIHRDLKASNVLLDSDMNAKISDFGLARTLG-GDETEANTTRVVGTYGYMSPEYQ 639
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ F SDV+SFGV + E+++ L L+G A Q + E+++
Sbjct 640 IDGYFSLKSDVFSFGVLVLEIVSGRRNRGFRNEEHKLNLLGHAWRQFLEDKAYEIIDEAV 699
Query 1133 RLPRPD-KCPCEVYHLMKNCWETEASFRPTFENLI 1166
D V H+ C + + RP ++
Sbjct 700 NESCTDISEVLRVIHIGLLCVQQDPKDRPNMSVVV 734
Score = 236 bits (601), Expect = 8e-64, Method: Composition-based stats.
Identities = 62/377 (16%), Positives = 115/377 (31%), Gaps = 65/377 (17%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
S+ + R L L + + LGQG VY+G L
Sbjct 434 ESSRVSSRKQEEEDLELPFLDLDTVSEATSGFSAGNKLGQGGFGPVYKGTLACGQ----- 488
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
V +K L + F L++++ H +L + G C
Sbjct 489 --------------------EVAVKRLSRTSRQGVEEFKNEIKLIAKLQHRNLVKILGYC 528
Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVH 732
V E +++ EY + LD ++ + + W ++ + + +A + YL ++H
Sbjct 529 VDEEERMLIYEYQPNKSLDSFIFDKERRRELDWPKRVEIIKGIARGMLYLHEDSRLRIIH 588
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPG 786
++ N+LL + K+SD G+ E V +++PE
Sbjct 589 RDLKASNVLLD-------SDMNAKISDFGLARTLGGDETEANTTRVVGTYGYMSPEYQID 641
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP------------ 834
G S D + FG +LEI G R+ K + R
Sbjct 642 GY--FSLKSDVFSFGVLVLEIVS-GRRNRGFRNEEHKLNLLGHAWRQFLEDKAYEIIDEA 698
Query 835 -EPSCPQLATLTS------QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
SC ++ + C+ +P RP+ ++ L+ +
Sbjct 699 VNESCTDISEVLRVIHIGLLCVQQDPKDRPNMSVVVLMLSSEMLLLDPRQPGFFNERNLL 758
Query 888 DPTVFHKRYLKKIRDLG 904
+
Sbjct 759 FSDTVSINLEIPSNNFQ 775
>sp|Q3E8W4|ANX2_ARATH Receptor-like protein kinase ANXUR2 OS=Arabidopsis
thaliana OX=3702 GN=ANX2 PE=1 SV=1
Length=858
Score = 253 bits (647), Expect = 3e-69, Method: Composition-based stats.
Identities = 78/310 (25%), Positives = 133/310 (43%), Gaps = 23/310 (7%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
+ + +G G FGKV D G VA+K + Q
Sbjct 506 CRRFSLSEIKHGTHNFDESNVIGVGGFGKVYKGVIDG-----GTKVAIKKSNPN-SEQGL 559
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLA 998
+ ++ EI++L L H+H++ G C++ GE + L+ +Y+ LG+LR++L R +
Sbjct 560 NEFETEIELLSRLRHKHLVSLIGYCDEGGE--MCLIYDYMSLGTLREHLYNTKRPQLTWK 617
Query 999 QLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ L A G+ YLH IHRD+ N+LLD + + K+ DFGL+K P + +
Sbjct 618 RRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILLDENWVAKVSDFGLSKTGPNMNGGH 677
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
V + PE + + SDV+SFGV L+E+L C P+ E + +
Sbjct 678 -VTTVVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLFEVL--CARPALNPSLSKEQVSLG 734
Query 1116 QGQMTVLR---LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK-- 1170
M R L ++++ + +C + + C RPT +++ L+
Sbjct 735 DWAMNCKRKGTLEDIIDPNLKGKINPECLKKFADTAEKCLSDSGLDRPTMGDVLWNLEFA 794
Query 1171 -TVHEKYQGQ 1179
+ E G
Sbjct 795 LQLQETADGS 804
Score = 219 bits (557), Expect = 1e-57, Method: Composition-based stats.
Identities = 58/291 (20%), Positives = 97/291 (33%), Gaps = 52/291 (18%)
Query 579 LSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S + + + +G G VY+G +
Sbjct 509 FSLSEIKHGTHNFDESNVIGVGGFGKVYKGVIDGG------------------------- 543
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+V +K +P+ F L+S++ H HL + G C G E ++ +Y+ G L
Sbjct 544 TKVAIKKSNPNSEQGLNEFETEIELLSRLRHKHLVSLIGYCDEGGEMCLIYDYMSLGTLR 603
Query 697 VWLRR-ERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTS 752
L +R + ++ +A A L YL ++H +V NILL +
Sbjct 604 EHLYNTKRPQLTWKRRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILLDE-------N 656
Query 753 PFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
K+SD G+ G +L PE L+ D + FG L E
Sbjct 657 WVAKVSDFGLSKTGPNMNGGHVTTVVKGSFGYLDPEYFR--RQQLTEKSDVYSFGVVLFE 714
Query 807 ICFDGEAPLQSRSPSEK-----EHFYQRQHRLPEPSCPQLA-TLTSQCLTY 851
+ A S S + +R+ L + P L + +CL
Sbjct 715 VLCARPALNPSLSKEQVSLGDWAMNCKRKGTLEDIIDPNLKGKINPECLKK 765
>sp|Q9FIU5|CRLK1_ARATH Calcium/calmodulin-regulated receptor-like
kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CRLK1 PE=1 SV=1
Length=440
Score = 243 bits (619), Expect = 3e-69, Method: Composition-based stats.
Identities = 73/326 (22%), Positives = 126/326 (39%), Gaps = 23/326 (7%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915
P + L+ + + K +G+G FG V
Sbjct 72 SPVKSSKNGRSVWLEGFSKRSNVISASGILEYSYRDLQKATCNFTTLIGQGAFGPVYKAQ 131
Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
TGE+VAVK L D Q ++ E+ +L L+H +++ G C ++G+
Sbjct 132 -----MSTGEIVAVKVLATD-SKQGEKEFQTEVMLLGRLHHRNLVNLIGYCAEKGQH--M 183
Query 976 LVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNV 1029
L+ Y+ GSL +L + + A + G+ YLH IHRD+ + N+
Sbjct 184 LIYVYMSKGSLASHLYSEKHEPLSWDLRVYIALDVARGLEYLHDGAVPPVIHRDIKSSNI 243
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
LLD ++ DFGL++ +R + PE + F SDV+ FGV
Sbjct 244 LLDQSMRARVADFGLSREEMVDKHAANIR----GTFGYLDPEYISTRTFTKKSDVYGFGV 299
Query 1090 TLYELLTHCDSSQSPPTKFLELIGI-AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148
L+EL+ ++P +EL+ + A + E+++ + EV
Sbjct 300 LLFELIAG----RNPQQGLMELVELAAMNAEEKVGWEEIVDSRLDGRYDLQEVNEVAAFA 355
Query 1149 KNCWETEASFRPTFENLIPILKTVHE 1174
C RP +++ +L V +
Sbjct 356 YKCISRAPRKRPNMRDIVQVLTRVIK 381
Score = 218 bits (556), Expect = 8e-61, Method: Composition-based stats.
Identities = 62/326 (19%), Positives = 120/326 (37%), Gaps = 58/326 (18%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
+ S+ + + + +GQG VY+ ++
Sbjct 102 EYSYRDLQKATCNFTTLIGQGAFGPVYKAQMSTGEI------------------------ 137
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V +KVL F L+ ++ H +L + G C +++++ Y+ G L
Sbjct 138 -VAVKVLATDSKQGEKEFQTEVMLLGRLHHRNLVNLIGYCAEKGQHMLIYVYMSKGSLAS 196
Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTS 752
L E+ H P++W ++ +A +A L YL + ++H ++ NILL + S
Sbjct 197 HLYSEK-HEPLSWDLRVYIALDVARGLEYLHDGAVPPVIHRDIKSSNILLDQ-------S 248
Query 753 PFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
+++D G+ + + +L PE + + + D +GFG L E+
Sbjct 249 MRARVADFGLSREEMVDKHAANIRGTFGYLDPEYIST--RTFTKKSDVYGFGVLLFELIA 306
Query 810 DGEAPLQSRS--------------PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855
G P Q E+ + R ++A +C++ P +
Sbjct 307 -GRNPQQGLMELVELAAMNAEEKVGWEEIVDSRLDGRYDLQEVNEVAAFAYKCISRAPRK 365
Query 856 RPSFRTILRDLTRLQPHNLADVLTVN 881
RP+ R I++ LTR+ N
Sbjct 366 RPNMRDIVQVLTRVIKVRHCRKRQKN 391
>sp|P24062|IGF1R_RAT Insulin-like growth factor 1 receptor OS=Rattus
norvegicus OX=10116 GN=Igf1r PE=2 SV=2
Length=1370
Score = 258 bits (660), Expect = 3e-69, Method: Composition-based stats.
Identities = 92/312 (29%), Positives = 147/312 (47%), Gaps = 29/312 (9%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALK 933
D D + + R+LG+G FG V E VA+K +
Sbjct 978 NPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVN 1037
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991
+ R + E +++ H+++ G QG+ +L ++ME + G L+ YL
Sbjct 1038 EAASMRERIEFLNEASVMKEFNCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSL 1095
Query 992 ----RHSI-----GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
+++ L++++ A +I +GMAYL+A ++HRDLAARN ++ D VKIGDF
Sbjct 1096 RPEVENNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDF 1155
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
G+ + + E +YYR G PV W +PE LK+ F SDVWSFGV L+E+ T
Sbjct 1156 GMTRDIYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIAT------ 1208
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
L ++ ++ + G L +PD CP ++ LM+ CW+ RP+F
Sbjct 1209 --------LAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSF 1260
Query 1163 ENLIPILKTVHE 1174
+I +K E
Sbjct 1261 LEIIGSIKDEME 1272
Score = 255 bits (651), Expect = 4e-68, Method: Composition-based stats.
Identities = 100/488 (20%), Positives = 173/488 (35%), Gaps = 87/488 (18%)
Query 425 RLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLI 484
+L +S+++ P D I GP+ RPE+ ++L +P LI
Sbjct 813 KLGCSASNFVFARTMPA----EGADDIPGPVTWE-----PRPENSIFLKWPEPENPNGLI 863
Query 485 LTVAQR-SQAPDGMQSL----RLRKFPIEQQD-----------GAFVLEGWGR------- 521
L + + + RK+ + + A L G G
Sbjct 864 LMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFF 923
Query 522 ------SFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLN 575
++ + L AL +L + + + + A +P +
Sbjct 924 YVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFS 983
Query 576 LSQL---SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
+ + V +++IT LGQG+ VYEG + +P
Sbjct 984 AADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEP---------------- 1027
Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
E RV +K ++ + + F AS+M + + H+ + GV +G +++ E +
Sbjct 1028 ---ETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMT 1084
Query 692 HGPLDVWLRRERGHV---------PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
G L +LR R V ++ + +A ++A ++YL VH ++ RN ++
Sbjct 1085 RGDLKSYLRSLRPEVENNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV 1144
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMD 796
A +K+ D G+ + + + W++PE L G +T D
Sbjct 1145 AE-------DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTHSD 1195
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854
W FG L EI E P Q S + F L P+ L L C Y P
Sbjct 1196 VWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPK 1255
Query 855 QRPSFRTI 862
RPSF I
Sbjct 1256 MRPSFLEI 1263
>sp|Q9UM73|ALK_HUMAN ALK tyrosine kinase receptor OS=Homo sapiens
OX=9606 GN=ALK PE=1 SV=3
Length=1620
Score = 259 bits (661), Expect = 3e-69, Method: Composition-based stats.
Identities = 95/344 (28%), Positives = 142/344 (41%), Gaps = 34/344 (10%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
Q P ++ + + + S SD ++ + IR LG G FG+V
Sbjct 1074 QSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEG 1133
Query 915 CYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
ND + VAVK L C Q + E I+ H++I++ G +
Sbjct 1134 QVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRF 1193
Query 974 LQLVMEYVPLGSLRDYLPR--------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
+ L E + G L+ +L S+ + LL A+ I G YL H+IHRD+A
Sbjct 1194 ILL--ELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIA 1251
Query 1026 ARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082
ARN LL + KIGDFG+A+ + YYR PV W PE E F +
Sbjct 1252 ARNCLLTCPGPGRVAKIGDFGMARDIYRA-SYYRKGGCAMLPVKWMPPEAFMEGIFTSKT 1310
Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
D WSFGV L+E+ + L + + + E + G R+ P CP
Sbjct 1311 DTWSFGVLLWEIFS--------------LGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPG 1356
Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
VY +M CW+ + RP F ++ ++ Y Q P V +
Sbjct 1357 PVYRIMTQCWQHQPEDRPNFAIILERIE-----YCTQDPDVINT 1395
Score = 254 bits (649), Expect = 9e-68, Method: Composition-based stats.
Identities = 77/314 (25%), Positives = 120/314 (38%), Gaps = 40/314 (13%)
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
S V +K IT + LG G VYEG++ G +D PL
Sbjct 1102 TSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQV---------SGMPNDPSPL------- 1145
Query 635 QELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+V +K L L F A ++S+ +H ++ GV ++ ++ E + G
Sbjct 1146 ---QVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGG 1202
Query 694 PLDVWLRRERGHVP------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
L +LR R M + VA+ +A YLE + +H ++ RN LL
Sbjct 1203 DLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLT---- 1258
Query 748 AEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFG 801
G K+ D G+ + + W+ PE G ++ D W FG
Sbjct 1259 CPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGI--FTSKTDTWSFG 1316
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSF 859
L EI G P S+S E F R+ P +CP + + +QC ++P RP+F
Sbjct 1317 VLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNF 1376
Query 860 RTILRDLTRLQPHN 873
IL +
Sbjct 1377 AIILERIEYCTQDP 1390
>sp|Q6I5Q6|RK185_ORYSJ Receptor-like cytoplasmic kinase 185 OS=Oryza
sativa subsp. japonica OX=39947 GN=RLCK185 PE=1 SV=1
Length=491
Score = 244 bits (622), Expect = 3e-69, Method: Composition-based stats.
Identities = 77/297 (26%), Positives = 131/297 (44%), Gaps = 20/297 (7%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
++ LGEG FG+V + G+ VAVK L + G Q + E+ +L L+
Sbjct 79 NFRQDCLLGEGGFGRVYKG-----HLENGQAVAVKQLDRN-GLQGNREFLVEVLMLSLLH 132
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEG 1010
H++++ G C D ++ LV E++PLGSL D+L + + + A +G
Sbjct 133 HDNLVNLIGYCADGDQR--LLVYEFMPLGSLEDHLHDIPPDKEPLDWNTRMKIAAGAAKG 190
Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ +LH + I+RD + N+LL K+ DFGLAK P G + + V +
Sbjct 191 LEFLHDKANPPVIYRDFKSSNILLGEGYHPKLSDFGLAKLGPVGDKTH-VSTRVMGTYGY 249
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVLR-LT 1125
APE + SDV+SFGV EL+T + + P L+ A+ R
Sbjct 250 CAPEYAMTGQLTVKSDVYSFGVVFLELITGRKAIDNTKPLGEQNLVAWARPLFKDRRKFP 309
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV-HEKYQGQAP 1181
++ + P + + + C + +A+ RP +++ L + + Y P
Sbjct 310 KMADPLLAGRFPMRGLYQALAVAAMCLQEQAATRPFIGDVVTALSYLASQTYDPNTP 366
Score = 230 bits (587), Expect = 2e-64, Method: Composition-based stats.
Identities = 71/358 (20%), Positives = 120/358 (34%), Gaps = 64/358 (18%)
Query 559 SNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618
+ I R A P + K Q LG+G VY+G L
Sbjct 50 KDAFIPRDANGQPIAAHTFTFRELAAATKNFRQDCLLGEGGFGRVYKGHLENGQ------ 103
Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678
V +K LD + F ++S + H +L + G C
Sbjct 104 -------------------AVAVKQLDRNGLQGNREFLVEVLMLSLLHHDNLVNLIGYCA 144
Query 679 RGPENIMVTEYVEHGPLDVWLRR---ERGHVPMAWKMVVAQQLASALSYLENK---NLVH 732
G + ++V E++ G L+ L ++ + +M +A A L +L +K +++
Sbjct 145 DGDQRLLVYEFMPLGSLEDHLHDIPPDKEPLDWNTRMKIAAGAAKGLEFLHDKANPPVIY 204
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERV-----ERIPWLAPECLPG 786
+ NILL G KLSD G+ LG + + V + APE
Sbjct 205 RDFKSSNILL-------GEGYHPKLSDFGLAKLGPVGDKTHVSTRVMGTYGYCAPEYAMT 257
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ------RQHRLPEPSCPQ 840
G L+ D + FG LE+ +A ++ E+ + + P+ + P
Sbjct 258 G--QLTVKSDVYSFGVVFLELITGRKAIDNTKPLGEQNLVAWARPLFKDRRKFPKMADPL 315
Query 841 LA------------TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
LA + + CL + RP ++ L+ L V
Sbjct 316 LAGRFPMRGLYQALAVAAMCLQEQAATRPFIGDVVTALSYLASQTYDPNTPVQHSRSN 373
>sp|Q1PDW3|LIPG1_ARATH Receptor-like kinase LIP1 OS=Arabidopsis
thaliana OX=3702 GN=LIP1 PE=1 SV=1
Length=636
Score = 248 bits (633), Expect = 3e-69, Method: Composition-based stats.
Identities = 88/370 (24%), Positives = 141/370 (38%), Gaps = 24/370 (6%)
Query 833 LPEPSCPQLATLTSQ---CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
+ P + S+ C T E R + P
Sbjct 3 IMMNCFPCFTSQKSRNAPCTTNETNDDNVEHDEFRPPVVATTKRTEEREPAEQQPPVKTF 62
Query 890 TVFH----KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
+ ++ LGEG FG+V Y T TG++VAVK L G +
Sbjct 63 NFRELATATKNFRQECLLGEGGFGRV----YKGTLQSTGQLVAVKQLDKH-GLHGNKEFL 117
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQL 1000
E+ L L H +++K G C D ++ LV EYV GSL+D+L + +
Sbjct 118 AEVLSLAKLEHPNLVKLIGYCADGDQR--LLVFEYVSGGSLQDHLYEQKPGQKPMDWITR 175
Query 1001 LLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ A +G+ YLH + I+RDL A N+LLD + K+ DFGL P + +
Sbjct 176 MKIAFGAAQGLDYLHDKVTPAVIYRDLKASNILLDAEFYPKLCDFGLHNLEPGTGDSLFL 235
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQ 1116
+ APE + SDV+SFGV L EL+T + + P L+ AQ
Sbjct 236 SSRVMDTYGYSAPEYTRGDDLTVKSDVYSFGVVLLELITGRRAIDTTKPNDEQNLVAWAQ 295
Query 1117 G-QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
R ++ + R ++ + + C + E + RP +++ L +
Sbjct 296 PIFKDPKRYPDMADPLLRKNFSERGLNQAVAITSMCLQEEPTARPLISDVMVALSFLSMS 355
Query 1176 YQGQAPSVFS 1185
+ P+
Sbjct 356 TEDGIPATVP 365
Score = 236 bits (603), Expect = 4e-65, Method: Composition-based stats.
Identities = 85/414 (21%), Positives = 139/414 (34%), Gaps = 67/414 (16%)
Query 523 FPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFH 582
F S + A + R + + + + +T N +L+
Sbjct 11 FTSQKSRNAPCTTNETNDDNVEHDEFRPPVVATTKRTEEREPAEQQPPVKTFNFRELAT- 69
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
K Q LG+G VY+G L+ G V +K
Sbjct 70 --ATKNFRQECLLGEGGFGRVYKGTLQSTGQ------------------------LVAVK 103
Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
LD F ++++ H +L + G C G + ++V EYV G L L +
Sbjct 104 QLDKHGLHGNKEFLAEVLSLAKLEHPNLVKLIGYCADGDQRLLVFEYVSGGSLQDHLYEQ 163
Query 703 R-GHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIK 756
+ G PM W +M +A A L YL +K +++ ++ NILL + K
Sbjct 164 KPGQKPMDWITRMKIAFGAAQGLDYLHDKVTPAVIYRDLKASNILLD-------AEFYPK 216
Query 757 LSDPGV-------GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
L D G+ G ++ + APE G + L+ D + FG LLE+
Sbjct 217 LCDFGLHNLEPGTGDSLFLSSRVMDTYGYSAPEYTRG--DDLTVKSDVYSFGVVLLELIT 274
Query 810 DGEAPLQSRSPSEKEHFYQRQ------HRLPEPSCPQLAT------------LTSQCLTY 851
A ++ E+ Q R P+ + P L +TS CL
Sbjct 275 GRRAIDTTKPNDEQNLVAWAQPIFKDPKRYPDMADPLLRKNFSERGLNQAVAITSMCLQE 334
Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
EPT RP ++ L+ L + P D ++ +
Sbjct 335 EPTARPLISDVMVALSFLSMSTEDGIPATVPMESFRDKSMSIALSRHGSCSVTP 388
>sp|Q9ZR08|Y4230_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At4g03230 OS=Arabidopsis thaliana OX=3702
GN=At4g03230 PE=3 SV=3
Length=852
Score = 253 bits (645), Expect = 4e-69, Method: Composition-based stats.
Identities = 77/286 (27%), Positives = 121/286 (42%), Gaps = 17/286 (6%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
+ LG+G FG V + + +AVK L C Q +K E+ ++
Sbjct 527 YATSNFSNANKLGQGGFGPVYKGMFPG-----DQEIAVKRLSR-CSGQGLEEFKNEVVLI 580
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI----GLAQLLLFAQQI 1007
L H ++++ G C EK L+ EY+P SL ++ + I
Sbjct 581 AKLQHRNLVRLLGYCVAGEEK--LLLYEYMPHKSLDFFIFDRKLCQRLDWKMRCNIILGI 638
Query 1008 CEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
G+ YLH IHRDL N+LLD + KI DFGLA+ G E
Sbjct 639 ARGLLYLHQDSRLRIIHRDLKTSNILLDEEMNPKISDFGLARIFG-GSETSANTNRVVGT 697
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLR 1123
+ +PE E F + SDV+SFGV + E ++ + P K L L+G A R
Sbjct 698 YGYMSPEYALEGLFSFKSDVFSFGVVVIETISGKRNTGFHEPEKSLSLLGHAWDLWKAER 757
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
ELL++ + + + ++ C + + + RPT N++ +L
Sbjct 758 GIELLDQALQESCETEGFLKCLNVGLLCVQEDPNDRPTMSNVVFML 803
Score = 225 bits (573), Expect = 1e-59, Method: Composition-based stats.
Identities = 52/284 (18%), Positives = 97/284 (34%), Gaps = 48/284 (17%)
Query 565 RGARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
R + + +++ + + + LGQG VY+G +
Sbjct 506 RFKQDDSQGIDVPSFELETILYATSNFSNANKLGQGGFGPVYKGMFPGDQ---------- 555
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
+ +K L F L++++ H +L + G CV G E
Sbjct 556 ---------------EIAVKRLSRCSGQGLEEFKNEVVLIAKLQHRNLVRLLGYCVAGEE 600
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENK---NLVHGNVCG 737
+++ EY+ H LD ++ + + WKM + +A L YL ++H ++
Sbjct 601 KLLLYEYMPHKSLDFFIFDRKLCQRLDWKMRCNIILGIARGLLYLHQDSRLRIIHRDLKT 660
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSL 791
NILL K+SD G+ + + V +++PE G
Sbjct 661 SNILLDEE-------MNPKISDFGLARIFGGSETSANTNRVVGTYGYMSPEYALEGL--F 711
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
S D + FG ++E G+ P + L +
Sbjct 712 SFKSDVFSFGVVVIETIS-GKRNTGFHEPEKSLSLLGHAWDLWK 754
>sp|Q60751|IGF1R_MOUSE Insulin-like growth factor 1 receptor OS=Mus
musculus OX=10090 GN=Igf1r PE=1 SV=3
Length=1373
Score = 258 bits (659), Expect = 4e-69, Method: Composition-based stats.
Identities = 92/313 (29%), Positives = 148/313 (47%), Gaps = 30/313 (10%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALK 933
D D + + R+LG+G FG V E VA+K +
Sbjct 978 NPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVN 1037
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991
+ R + E +++ H+++ G QG+ +L ++ME + G L+ YL
Sbjct 1038 EAASMRERIEFLNEASVMKEFNCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSL 1095
Query 992 -----RHSI-----GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
++++ L++++ A +I +GMAYL+A ++HRDLAARN ++ D VKIGD
Sbjct 1096 RPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGD 1155
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FG+ + + E +YYR G PV W +PE LK+ F SDVWSFGV L+E+ T
Sbjct 1156 FGMTRDIYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIAT----- 1209
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
L ++ ++ + G L +PD CP ++ LM+ CW+ RP+
Sbjct 1210 ---------LAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPS 1260
Query 1162 FENLIPILKTVHE 1174
F +I +K E
Sbjct 1261 FLEIIGSIKDEME 1273
Score = 254 bits (650), Expect = 6e-68, Method: Composition-based stats.
Identities = 100/489 (20%), Positives = 173/489 (35%), Gaps = 88/489 (18%)
Query 425 RLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLI 484
+L +S+++ P D I GP+ RPE+ ++L +P LI
Sbjct 813 KLGCSASNFVFARTMPA----EGADDIPGPVTWE-----PRPENSIFLKWPEPENPNGLI 863
Query 485 LTVAQR-SQAPDGMQSL----RLRKFPIEQQD-----------GAFVLEGWGR------- 521
L + + + RK+ + + A L G G
Sbjct 864 LMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFF 923
Query 522 ------SFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLN 575
++ + L AL +L + + + + A +P +
Sbjct 924 YVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFS 983
Query 576 LSQL---SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
+ + V +++IT LGQG+ VYEG + +P
Sbjct 984 AADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEP---------------- 1027
Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
E RV +K ++ + + F AS+M + + H+ + GV +G +++ E +
Sbjct 1028 ---ETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMT 1084
Query 692 HGPLDVWLRRERGHV----------PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
G L +LR R V ++ + +A ++A ++YL VH ++ RN +
Sbjct 1085 RGDLKSYLRSLRPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCM 1144
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAM 795
+A +K+ D G+ + + + W++PE L G +T
Sbjct 1145 VAE-------DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTHS 1195
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEP 853
D W FG L EI E P Q S + F L P+ L L C Y P
Sbjct 1196 DVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNP 1255
Query 854 TQRPSFRTI 862
RPSF I
Sbjct 1256 KMRPSFLEI 1264
>sp|Q01973|ROR1_HUMAN Inactive tyrosine-protein kinase transmembrane
receptor ROR1 OS=Homo sapiens OX=9606 GN=ROR1 PE=1 SV=2
Length=937
Score = 254 bits (649), Expect = 5e-69, Method: Composition-based stats.
Identities = 82/291 (28%), Positives = 135/291 (46%), Gaps = 35/291 (12%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+ +LGE FGK+ ++VA+K LK PQ + ++QE ++ L+H +
Sbjct 475 FMEELGECAFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPN 534
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------------------RHSIGLAQL 1000
I+ G E+ + ++ EY+ G L ++L + S+
Sbjct 535 IVCLLGAVTQ--EQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDF 592
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
L A QI GM YL + ++H+DLAARN+L+ VKI D GL++ + +YYRV+
Sbjct 593 LHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIY-SADYYRVQSK 651
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
P+ W PE + KF SD+WSFGV L+E+ + +
Sbjct 652 SLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQ--------------PYYGFS 697
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ E++ + + LP + CP +Y LM CW S RP F+++ L++
Sbjct 698 NQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRS 748
Score = 237 bits (604), Expect = 2e-63, Method: Composition-based stats.
Identities = 70/312 (22%), Positives = 120/312 (38%), Gaps = 54/312 (17%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+ + + + LG+ +Y+G L +PG D Q
Sbjct 461 PKSKAKELPLSAVRFMEELGECAFGKIYKGHL------------------YLPGMDHAQ- 501
Query 637 LRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K L ++ F + ASLM+++ H ++ + G + M+ EY+ G L
Sbjct 502 -LVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDL 560
Query 696 DVWLRRERGHVPMAWK----------------MVVAQQLASALSYLENKNLVHGNVCGRN 739
+L H + + +A Q+A+ + YL + VH ++ RN
Sbjct 561 HEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARN 620
Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLST 793
IL+ G +K+SD G+ S + I W+ PE + G S+
Sbjct 621 ILI-------GEQLHVKISDLGLSREIYSADYYRVQSKSLLPIRWMPPEAIMYG--KFSS 671
Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE--PSCPQLATLTSQCLTY 851
D W FG L EI G P S E +++ LP P++ +L ++C
Sbjct 672 DSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNE 731
Query 852 EPTQRPSFRTIL 863
P++RP F+ I
Sbjct 732 IPSRRPRFKDIH 743
>sp|O65476|CRK16_ARATH Putative cysteine-rich receptor-like protein
kinase 16 OS=Arabidopsis thaliana OX=3702 GN=CRK16 PE=3
SV=2
Length=662
Score = 248 bits (634), Expect = 5e-69, Method: Composition-based stats.
Identities = 73/286 (26%), Positives = 109/286 (38%), Gaps = 18/286 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+K LG G FG+V + G VAVK L G Q +K E+ ++ L
Sbjct 333 NNFQKSNKLGHGGFGEVFKGTF-----PNGTEVAVKRLSKISG-QGEEEFKNEVLLVAKL 386
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL----RDYLPRHSIGLAQLLLFAQQICEG 1010
H ++++ G + EK LV EY+P SL D+ R + + + G
Sbjct 387 QHRNLVRLLGFSVEGEEK--ILVYEYMPNKSLDYFLFDHRRRGQLDWRTRYNIIRGVTRG 444
Query 1011 MAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH IHRDL A N+LLD D KI DFG+A+ +
Sbjct 445 ILYLHQDSRLTIIHRDLKAGNILLDVDMNPKIADFGVARNFRVDQTEATT-GRVVGTFGY 503
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLT 1125
PE + +F SDV+SFGV + E++ S L+
Sbjct 504 MPPEYVANGQFSMKSDVYSFGVLILEIIVGKKSSSFHEIDGSVGNLVTYVWRLWNNESFL 563
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
EL++ H+ C + + RPT + +L
Sbjct 564 ELVDPAMGESYDKDEVIRCIHISLLCVQENPADRPTMSTVFQMLTN 609
Score = 232 bits (592), Expect = 2e-63, Method: Composition-based stats.
Identities = 59/324 (18%), Positives = 105/324 (32%), Gaps = 65/324 (20%)
Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
T Q F ++ + + LG G V++G
Sbjct 317 TSGSLQFDFKAIEAATNNFQKSNKLGHGGFGEVFKGT----------------------- 353
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
V +K L F L++++ H +L + G V G E I+V EY+
Sbjct 354 --FPNGTEVAVKRLSKISGQGEEEFKNEVLLVAKLQHRNLVRLLGFSVEGEEKILVYEYM 411
Query 691 EHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745
+ LD +L R RG + + + + + + YL + ++H ++ NILL
Sbjct 412 PNKSLDYFLFDHRRRGQLDWRTRYNIIRGVTRGILYLHQDSRLTIIHRDLKAGNILLD-- 469
Query 746 GLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWG 799
K++D GV + V ++ PE + G S D +
Sbjct 470 -----VDMNPKIADFGVARNFRVDQTEATTGRVVGTFGYMPPEYVANG--QFSMKSDVYS 522
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC------PQLAT---------- 843
FG +LEI ++ + RL P +
Sbjct 523 FGVLILEIIVGKKSSSFHEIDGSVGNLVTYVWRLWNNESFLELVDPAMGESYDKDEVIRC 582
Query 844 --LTSQCLTYEPTQRPSFRTILRD 865
++ C+ P RP+ T+ +
Sbjct 583 IHISLLCVQENPADRPTMSTVFQM 606
>sp|Q63474|DDR1_RAT Epithelial discoidin domain-containing receptor
1 OS=Rattus norvegicus OX=10116 GN=Ddr1 PE=2 SV=1
Length=910
Score = 253 bits (647), Expect = 5e-69, Method: Composition-based stats.
Identities = 99/317 (31%), Positives = 143/317 (45%), Gaps = 45/317 (14%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD------------PTNDGTGEMVAVKALKA 934
F + L+ LGEG FG+V L + G +VAVK L+
Sbjct 597 PPRVDFPRSRLRFKEKLGEGQFGEVHLCEVEDPQDLVTSDFPISVQKGHPLLVAVKILRP 656
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993
D R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L H
Sbjct 657 DATKNARNDFLKEVKIMSRLKDLNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSAHQ 714
Query 994 -------------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034
+I LL QI GM YL +++HRDLA RN L+ +
Sbjct 715 LENKVTQGLPGDRESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLVGEN 774
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
+KI DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+
Sbjct 775 FTIKIADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEV 833
Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER--LPRPDKCPCEVYHLMKNCW 1152
L C +S P L + + R ++G + L RP CP +Y LM CW
Sbjct 834 LMLC---RSQPFGQLTDEQVIENAGEFFR-----DQGRQVYLSRPPACPQTLYELMLRCW 885
Query 1153 ETEASFRPTFENLIPIL 1169
E RP F L L
Sbjct 886 SREPEQRPPFSQLHRFL 902
Score = 227 bits (578), Expect = 3e-60, Method: Composition-based stats.
Identities = 74/316 (23%), Positives = 123/316 (39%), Gaps = 52/316 (16%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ + LG+G V+ + E+ + +G L V +K+L
Sbjct 603 PRSRLRFKEKLGEGQFGEVH--------LCEVEDPQDLVTSDFPISVQKGHPLLVAVKIL 654
Query 645 DPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
P A F + +MS++ ++ + GVCV+ M+T+Y+E+G L+ +L +
Sbjct 655 RPDATKNARNDFLKEVKIMSRLKDLNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 714
Query 704 GHVPMAW------------------KMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
+ + V Q+AS + YL N VH ++ RN L+
Sbjct 715 LENKVTQGLPGDRESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLV--- 771
Query 746 GLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWG 799
G + IK++D G+ + + V I W+A EC+ G +TA D W
Sbjct 772 ----GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG--KFTTASDVWA 825
Query 800 FGATLLEI-CFDGEAPLQSRSPSEKE----HFYQRQHRL-----PEPSCPQLATLTSQCL 849
FG TL E+ P + + F++ Q R P L L +C
Sbjct 826 FGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQTLYELMLRCW 885
Query 850 TYEPTQRPSFRTILRD 865
+ EP QRP F + R
Sbjct 886 SREPEQRPPFSQLHRF 901
>sp|Q9NYL2|M3K20_HUMAN Mitogen-activated protein kinase kinase
kinase 20 OS=Homo sapiens OX=9606 GN=MAP3K20 PE=1 SV=3
Length=800
Score = 251 bits (641), Expect = 6e-69, Method: Composition-based stats.
Identities = 82/283 (29%), Positives = 132/283 (47%), Gaps = 40/283 (14%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+ + G G FG V + + VAVK L ++E +IL L H
Sbjct 17 QFFENCGGGSFGSVYRAKWISQDK----EVAVKKLLK---------IEKEAEILSVLSHR 63
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYL 1014
+II++ G + + +V EY LGSL DY+ + + + ++ +A + +GM YL
Sbjct 64 NIIQFYGVILEP--PNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYL 121
Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
H + IHRDL +RNV++ D ++KI DFG ++ + W APE
Sbjct 122 HMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN-----HTTHMSLVGTFPWMAPE 176
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
++ D +S+GV L+E+LT P K LE + +A ++E+
Sbjct 177 VIQSLPVSETCDTYSYGVVLWEMLTR-----EVPFKGLEGLQVAWL---------VVEKN 222
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
ERL P CP L+ CWE +A RP+F+ +I IL+++
Sbjct 223 ERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSN 265
Score = 211 bits (537), Expect = 2e-55, Method: Composition-based stats.
Identities = 65/334 (19%), Positives = 124/334 (37%), Gaps = 51/334 (15%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
SF ++ ++ + G G+ +VY + Q+ V
Sbjct 7 SFVQIKFDDLQFFENCGGGSFGSVYRAKWI------------------------SQDKEV 42
Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+K L L + A ++S +SH ++ +GV + P +VTEY G L ++
Sbjct 43 AVKKL--------LKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYI 94
Query 700 RRERG-HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFI 755
R + M M A +A + YL + ++H ++ RN+++A G+ +
Sbjct 95 NSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV-------L 147
Query 756 KLSDPGVGLGALSREER--VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
K+ D G V PW+APE + + +S D + +G L E+ E
Sbjct 148 KICDFGASRFHNHTTHMSLVGTFPWMAPEVIQ--SLPVSETCDTYSYGVVLWEMLTR-EV 204
Query 814 PLQSRSPSEKEHF---YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P + + + +P A L QC + +RPSF+ I+ L +
Sbjct 205 PFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMS 264
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
+ ++ + L++++ L
Sbjct 265 NDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLE 298
>sp|Q9LYN8|EMS1_ARATH Leucine-rich repeat receptor protein kinase
EMS1 OS=Arabidopsis thaliana OX=3702 GN=EMS1 PE=1 SV=1
Length=1192
Score = 256 bits (655), Expect = 6e-69, Method: Composition-based stats.
Identities = 72/288 (25%), Positives = 122/288 (42%), Gaps = 20/288 (7%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+ K +G+G FG V C + VAVK L ++ Q + E++ L +
Sbjct 915 DHFSKKNIIGDGGFGTVYKACLPGE-----KTVAVKKL-SEAKTQGNREFMAEMETLGKV 968
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICE 1009
H +++ G C EK LV EY+ GSL +L + + ++ L A
Sbjct 969 KHPNLVSLLGYCSFSEEK--LLVYEYMVNGSLDHWLRNQTGMLEVLDWSKRLKIAVGAAR 1026
Query 1010 GMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G+A+LH H IHRD+ A N+LLD D K+ DFGLA+ + + V
Sbjct 1027 GLAFLHHGFIPHIIHRDIKASNILLDGDFEPKVADFGLARLISACESH--VSTVIAGTFG 1084
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRL 1124
+ PE + + DV+SFGV L EL+T + ++ L+G A ++ +
Sbjct 1085 YIPPEYGQSARATTKGDVYSFGVILLELVTGKEPTGPDFKESEGGNLVGWAIQKINQGKA 1144
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
++++ + + C + RP +++ LK +
Sbjct 1145 VDVIDPLLVSVALKNSQLRLLQIAMLCLAETPAKRPNMLDVLKALKEI 1192
Score = 222 bits (566), Expect = 7e-58, Method: Composition-based stats.
Identities = 61/307 (20%), Positives = 108/307 (35%), Gaps = 63/307 (21%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
++ + +G G VY+ L E V +K L
Sbjct 913 ATDHFSKKNIIGDGGFGTVYKACLPG-------------------------EKTVAVKKL 947
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ F + +V H +L + G C E ++V EY+ +G LD WLR + G
Sbjct 948 SEAKTQGNREFMAEMETLGKVKHPNLVSLLGYCSFSEEKLLVYEYMVNGSLDHWLRNQTG 1007
Query 705 ---HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ + ++ +A A L++L + +++H ++ NILL K++
Sbjct 1008 MLEVLDWSKRLKIAVGAARGLAFLHHGFIPHIIHRDIKASNILLD-------GDFEPKVA 1060
Query 759 DPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
D G+ + E V ++ PE G + +T D + FG LLE+ E
Sbjct 1061 DFGLARLISACESHVSTVIAGTFGYIPPEY--GQSARATTKGDVYSFGVILLELVTGKEP 1118
Query 814 PLQSRSPSEKEHFYQR------QHRLPEPSCPQLAT------------LTSQCLTYEPTQ 855
SE + Q + + P L + + CL P +
Sbjct 1119 TGPDFKESEGGNLVGWAIQKINQGKAVDVIDPLLVSVALKNSQLRLLQIAMLCLAETPAK 1178
Query 856 RPSFRTI 862
RP+ +
Sbjct 1179 RPNMLDV 1185
>sp|Q9ESL4|M3K20_MOUSE Mitogen-activated protein kinase kinase
kinase 20 OS=Mus musculus OX=10090 GN=Map3k20 PE=1 SV=1
Length=802
Score = 251 bits (641), Expect = 6e-69, Method: Composition-based stats.
Identities = 82/283 (29%), Positives = 132/283 (47%), Gaps = 40/283 (14%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+ + G G FG V + + VAVK L ++E +IL L H
Sbjct 17 QFFENCGGGSFGSVYRAKWISQDK----EVAVKKLLK---------IEKEAEILSVLSHR 63
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYL 1014
+II++ G + + +V EY LGSL DY+ + + + ++ +A + +GM YL
Sbjct 64 NIIQFYGVILEP--PNYGIVTEYASLGSLYDYINSNRSEEMDMEHIMTWATDVAKGMHYL 121
Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
H + IHRDL +RNV++ D ++KI DFG ++ + W APE
Sbjct 122 HMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN-----HTTHMSLVGTFPWMAPE 176
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
++ D +S+GV L+E+LT P K LE + +A ++E+
Sbjct 177 VIQSLPVSETCDTYSYGVVLWEMLTR-----EVPFKGLEGLQVAWL---------VVEKN 222
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
ERL P CP L+ CWE +A RP+F+ +I IL+++
Sbjct 223 ERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSN 265
Score = 209 bits (533), Expect = 5e-55, Method: Composition-based stats.
Identities = 65/334 (19%), Positives = 124/334 (37%), Gaps = 51/334 (15%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
SF ++ ++ + G G+ +VY + Q+ V
Sbjct 7 SFVQIKFDDLQFFENCGGGSFGSVYRAKWI------------------------SQDKEV 42
Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+K L L + A ++S +SH ++ +GV + P +VTEY G L ++
Sbjct 43 AVKKL--------LKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYI 94
Query 700 RRERG-HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFI 755
R + M M A +A + YL + ++H ++ RN+++A G+ +
Sbjct 95 NSNRSEEMDMEHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV-------L 147
Query 756 KLSDPGVGLGALSREER--VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
K+ D G V PW+APE + + +S D + +G L E+ E
Sbjct 148 KICDFGASRFHNHTTHMSLVGTFPWMAPEVIQ--SLPVSETCDTYSYGVVLWEMLTR-EV 204
Query 814 PLQSRSPSEKEHF---YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P + + + +P A L QC + +RPSF+ I+ L +
Sbjct 205 PFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMS 264
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
+ ++ + L++++ L
Sbjct 265 NDTNLPDQCNSFLHNKAEWRCEIEATLERLKKLE 298
>sp|Q9FID8|Y5900_ARATH Putative receptor-like protein kinase At5g39000
OS=Arabidopsis thaliana OX=3702 GN=At5g39000 PE=3 SV=1
Length=873
Score = 253 bits (645), Expect = 7e-69, Method: Composition-based stats.
Identities = 76/294 (26%), Positives = 126/294 (43%), Gaps = 20/294 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V Y DG +VAVK L+ Q ++ E+++L L H H++
Sbjct 524 IGVGGFGSV----YKGQIDGGATLVAVKRLEI-TSNQGAKEFETELEMLSKLRHVHLVSL 578
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------SIGLAQLLLFAQQICEGMAYLHA 1016
G C++ E + LV EY+P G+L+D+L R + + L G+ YLH
Sbjct 579 IGYCDEDNE--MVLVYEYMPHGTLKDHLFRRDKTSDPPLSWKRRLEICIGAARGLQYLHT 636
Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRD+ N+LLD + + K+ DFGL++ P V + PE
Sbjct 637 GAKYTIIHRDIKTTNILLDENFVTKVSDFGLSRVGPTSASQTHVSTVVKGTFGYLDPEYY 696
Query 1074 KEYKFYYASDVWSFGVTLYELL-THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ SDV+SFGV L E+L QS P + +LI + + ++++
Sbjct 697 RRQVLTEKSDVYSFGVVLLEVLCCRPIRMQSVPPEQADLIRWVKSNYRRGTVDQIIDSDL 756
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK---TVHEKYQGQAPSV 1183
+ + C + RP +++ L+ +HE + + +V
Sbjct 757 SADITSTSLEKFCEIAVRCVQDRGMERPPMNDVVWALEFALQLHETAKKKNDNV 810
Score = 223 bits (568), Expect = 4e-59, Method: Composition-based stats.
Identities = 67/348 (19%), Positives = 123/348 (35%), Gaps = 70/348 (20%)
Query 550 CCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGR 607
C LP +++N + A++ P L + S + + +G G +VY+G+
Sbjct 481 CPLPHGTDSTN---TKPAKSLPADL-CRRFSIFEIKSATNDFEDKLIIGVGGFGSVYKGQ 536
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667
+ G V +K L+ + + A F ++S++ H
Sbjct 537 I------------------------DGGATLVAVKRLEITSNQGAKEFETELEMLSKLRH 572
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG--HVPMAW--KMVVAQQLASALS 723
HL + G C E ++V EY+ HG L L R P++W ++ + A L
Sbjct 573 VHLVSLIGYCDEDNEMVLVYEYMPHGTLKDHLFRRDKTSDPPLSWKRRLEICIGAARGLQ 632
Query 724 YLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV------- 773
YL ++H ++ NILL + K+SD G+ + +
Sbjct 633 YLHTGAKYTIIHRDIKTTNILLDE-------NFVTKVSDFGLSRVGPTSASQTHVSTVVK 685
Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ--RQH 831
+L PE L+ D + FG LLE+ +QS P + + +
Sbjct 686 GTFGYLDPEYYRRQV--LTEKSDVYSFGVVLLEVLCCRPIRMQSVPPEQADLIRWVKSNY 743
Query 832 R---------------LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
R + S + + +C+ +RP ++
Sbjct 744 RRGTVDQIIDSDLSADITSTSLEKFCEIAVRCVQDRGMERPPMNDVVW 791
>sp|C0LGU1|Y5374_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At5g37450 OS=Arabidopsis thaliana OX=3702
GN=At5g37450 PE=1 SV=1
Length=959
Score = 254 bits (648), Expect = 7e-69, Method: Composition-based stats.
Identities = 72/280 (26%), Positives = 120/280 (43%), Gaps = 22/280 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G +GKV G +VAVK Q + + EI++L L+H +++
Sbjct 637 IGRGGYGKVYKGHLPG-----GLVVAVKR-AEQGSLQGQKEFFTEIELLSRLHHRNLVSL 690
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
G C+ +GE+ LV EY+P GSL+D L R + LA L A G+ YLH +
Sbjct 691 LGYCDQKGEQ--MLVYEYMPNGSLQDALSARFRQPLSLALRLRIALGSARGILYLHTEAD 748
Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAV---PEGHEYYRVREDGDSPVFWYAPECL 1073
IHRD+ N+LLD+ K+ DFG++K + G + V + PE
Sbjct 749 PPIIHRDIKPSNILLDSKMNPKVADFGISKLIALDGGGVQRDHVTTIVKGTPGYVDPEYY 808
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
++ SDV+S G+ E+LT P + ++ + +++R
Sbjct 809 LSHRLTEKSDVYSLGIVFLEILTGMR----PISHGRNIVREVNEACDAGMMMSVIDRSM- 863
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
++C L C + RP ++ L+ ++
Sbjct 864 GQYSEECVKRFMELAIRCCQDNPEARPWMLEIVRELENIY 903
Score = 227 bits (578), Expect = 5e-60, Method: Composition-based stats.
Identities = 66/343 (19%), Positives = 117/343 (34%), Gaps = 69/343 (20%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
P P N+ ++G N ++L + LS +G+G VY+G L
Sbjct 605 PLPKPPMNMESVKG-------YNFTELDS---ATSSFSDLSQIGRGGYGKVYKGHLPGG- 653
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672
L V +K + F+ L+S++ H +L
Sbjct 654 ------------------------LVVAVKRAEQGSLQGQKEFFTEIELLSRLHHRNLVS 689
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLE---NK 728
+ G C + E ++V EY+ +G L L R + +A ++ +A A + YL +
Sbjct 690 LLGYCDQKGEQMLVYEYMPNGSLQDALSARFRQPLSLALRLRIALGSARGILYLHTEADP 749
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERV----ERIPW 778
++H ++ NILL K++D G+ G + R+ +
Sbjct 750 PIIHRDIKPSNILLDSK-------MNPKVADFGISKLIALDGGGVQRDHVTTIVKGTPGY 802
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRL---- 833
+ PE ++ L+ D + G LEI R+ E +
Sbjct 803 VDPEYYL--SHRLTEKSDVYSLGIVFLEILTGMRPISHGRNIVREVNEACDAGMMMSVID 860
Query 834 ------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
E + L +C P RP I+R+L +
Sbjct 861 RSMGQYSEECVKRFMELAIRCCQDNPEARPWMLEIVRELENIY 903
>sp|O65483|CRK24_ARATH Cysteine-rich receptor-like protein kinase
24 OS=Arabidopsis thaliana OX=3702 GN=CRK24 PE=3 SV=2
Length=636
Score = 247 bits (631), Expect = 8e-69, Method: Composition-based stats.
Identities = 76/299 (25%), Positives = 113/299 (38%), Gaps = 18/299 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+ LG G FG+V + G VAVK L G Q +K E+ ++ L
Sbjct 310 CNFHNVNKLGHGGFGEVYKGTF-----PNGTEVAVKRLSKTSG-QGEEEFKNEVFLVAKL 363
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEG 1010
H +++K G EK LV E++P SL +L + + + I G
Sbjct 364 QHRNLVKLLGYAVKGDEK--ILVYEFLPNKSLDHFLFDPVKKGQLDWTRRYNIINGITRG 421
Query 1011 MAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH IHRDL A N+LLD D KI DFG+A+ + +
Sbjct 422 IVYLHQDSRLTIIHRDLKAGNILLDADMNPKIVDFGVARNFRVDQTEATTAR-VVGTIGY 480
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK--FLELIGIAQGQMTVLRLT 1125
PE + +F SDV+SFGV + E++ +S T L+ L
Sbjct 481 MPPEYVTNGQFSTKSDVYSFGVLILEIIGGKKNSSINETDGSISNLVTYVWRLWNNEPLL 540
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
EL++ H+ C + + RPT + +L P F
Sbjct 541 ELVDAPMGENYDRNEVIRCIHIGLLCVQENPADRPTMSTVFHMLTNTSITLHVPQPPGF 599
Score = 220 bits (561), Expect = 1e-59, Method: Composition-based stats.
Identities = 61/350 (17%), Positives = 108/350 (31%), Gaps = 65/350 (19%)
Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
T Q F ++ ++ LG G VY+G
Sbjct 294 TSGSLQFEFKAIEAATCNFHNVNKLGHGGFGEVYKGT----------------------- 330
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
V +K L + F L++++ H +L + G V+G E I+V E++
Sbjct 331 --FPNGTEVAVKRLSKTSGQGEEEFKNEVFLVAKLQHRNLVKLLGYAVKGDEKILVYEFL 388
Query 691 EHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745
+ LD +L ++G + + + + + YL + ++H ++ NILL
Sbjct 389 PNKSLDHFLFDPVKKGQLDWTRRYNIINGITRGIVYLHQDSRLTIIHRDLKAGNILLD-- 446
Query 746 GLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWG 799
K+ D GV + V I ++ PE + G ST D +
Sbjct 447 -----ADMNPKIVDFGVARNFRVDQTEATTARVVGTIGYMPPEYVTNG--QFSTKSDVYS 499
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP------------------EPSCPQL 841
FG +LEI + + + + RL +
Sbjct 500 FGVLILEIIGGKKNSSINETDGSISNLVTYVWRLWNNEPLLELVDAPMGENYDRNEVIRC 559
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV 891
+ C+ P RP+ T+ LT P
Sbjct 560 IHIGLLCVQENPADRPTMSTVFHMLTNTSITLHVPQPPGFVFRVRFKPNP 609
>sp|Q9XEC7|CRK37_ARATH Cysteine-rich receptor-like protein kinase
37 OS=Arabidopsis thaliana OX=3702 GN=CRK37 PE=3 SV=1
Length=646
Score = 247 bits (631), Expect = 8e-69, Method: Composition-based stats.
Identities = 71/321 (22%), Positives = 125/321 (39%), Gaps = 21/321 (7%)
Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922
+ + + V LG+G FG V
Sbjct 311 RKQSHTIINDVFDSNNGQSMLRFDLRMIVTATNNFSLENKLGQGGFGSVYKGIL-----P 365
Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982
+G+ +AVK L+ G +K E+ +L L H +++K G C ++ E+ LV E+VP
Sbjct 366 SGQEIAVKRLRKGSGQGGME-FKNEVLLLTRLQHRNLVKLLGFCNEKDEE--ILVYEFVP 422
Query 983 LGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDR 1035
SL ++ R + + + G+ YLH IHRDL A N+LLD +
Sbjct 423 NSSLDHFIFDEEKRRVLTWDVRYTIIEGVARGLLYLHEDSQLRIIHRDLKASNILLDAEM 482
Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
K+ DFG+A+ + + APE +F SDV+SFGV L E++
Sbjct 483 NPKVADFGMARLFDMDETRGQTSR-VVGTYGYMAPEYATYGQFSTKSDVYSFGVMLLEMI 541
Query 1096 THCDSSQSPPTKFLELIGIA---QGQMTVLRLTELLERGERLP--RPDKCPCEVYHLMKN 1150
+ + + + E + + R E+++ ++ H+
Sbjct 542 SGKSNKKLEKEEEEEEEELPAFVWKRWIEGRFAEIIDPLAAPSNNISINEVMKLIHIGLL 601
Query 1151 CWETEASFRPTFENLIPILKT 1171
C + + S RP+ +++ L+
Sbjct 602 CVQEDISKRPSINSILFWLER 622
Score = 236 bits (601), Expect = 7e-65, Method: Composition-based stats.
Identities = 66/366 (18%), Positives = 119/366 (33%), Gaps = 67/366 (18%)
Query 461 QAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSL----RLRKFPIEQQDGAFVL 516
Q + G + S R ++ R+ P +
Sbjct 227 QKQFWGRQGGGVSRPSC----------YFRWDLYPYYRAFDNVVRVPAPPPQASSTIIDY 276
Query 517 EGWGRSF--PSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTL 574
+SF ++ + L+ FS +R ++ +I + +++
Sbjct 277 GRDEKSFQGSNIAIIVVPSVINLIIFVVLIFSWKR------KQSHTIINDVFDSNNGQSM 330
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
L + + LGQG +VY+G L
Sbjct 331 LRFDLRMIVTATNNFSLENKLGQGGFGSVYKGILPSGQ---------------------- 368
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+ +K L + F L++++ H +L + G C E I+V E+V +
Sbjct 369 ---EIAVKRLRKGSGQGGMEFKNEVLLLTRLQHRNLVKLLGFCNEKDEEILVYEFVPNSS 425
Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAE 749
LD ++ E + W + + + +A L YL ++H ++ NILL
Sbjct 426 LDHFIFDEEKRRVLTWDVRYTIIEGVARGLLYLHEDSQLRIIHRDLKASNILLD------ 479
Query 750 GTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
K++D G+ E R V ++APE G ST D + FG
Sbjct 480 -AEMNPKVADFGMARLFDMDETRGQTSRVVGTYGYMAPEYATYG--QFSTKSDVYSFGVM 536
Query 804 LLEICF 809
LLE+
Sbjct 537 LLEMIS 542
>sp|P97793|ALK_MOUSE ALK tyrosine kinase receptor OS=Mus musculus
OX=10090 GN=Alk PE=1 SV=2
Length=1621
Score = 258 bits (658), Expect = 8e-69, Method: Composition-based stats.
Identities = 95/344 (28%), Positives = 142/344 (41%), Gaps = 34/344 (10%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
Q P ++ + + + S SD ++ + IR LG G FG+V
Sbjct 1078 QSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEG 1137
Query 915 CYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
ND + VAVK L C Q + E I+ H++I++ G +
Sbjct 1138 QVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRF 1197
Query 974 LQLVMEYVPLGSLRDYLPRH--------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
+ L E + G L+ +L S+ + LL A+ I G YL H+IHRD+A
Sbjct 1198 ILL--ELMAGGDLKSFLRETRPRPNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIA 1255
Query 1026 ARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082
ARN LL + KIGDFG+A+ + YYR PV W PE E F +
Sbjct 1256 ARNCLLTCPGAGRIAKIGDFGMARDIYRA-SYYRKGGCAMLPVKWMPPEAFMEGIFTSKT 1314
Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
D WSFGV L+E+ + L + + + E + G R+ P CP
Sbjct 1315 DTWSFGVLLWEIFS--------------LGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPG 1360
Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
VY +M CW+ + RP F ++ ++ Y Q P V +
Sbjct 1361 PVYRIMTQCWQHQPEDRPNFAIILERIE-----YCTQDPDVINT 1399
Score = 254 bits (649), Expect = 1e-67, Method: Composition-based stats.
Identities = 79/314 (25%), Positives = 123/314 (39%), Gaps = 40/314 (13%)
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
S V +K IT + LG G VYEG++ G +D PL
Sbjct 1106 TSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQV---------SGMPNDPSPL------- 1149
Query 635 QELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+V +K L L F A ++S+ +H ++ GV ++ ++ E + G
Sbjct 1150 ---QVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAGG 1206
Query 694 PLDVWLR--RERGHVPMAWKM----VVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
L +LR R R + P + M VA+ +A YLE + +H ++ RN LL
Sbjct 1207 DLKSFLRETRPRPNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLT---- 1262
Query 748 AEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFG 801
G K+ D G+ + + W+ PE G ++ D W FG
Sbjct 1263 CPGAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGI--FTSKTDTWSFG 1320
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSF 859
L EI G P S+S E F R+ P +CP + + +QC ++P RP+F
Sbjct 1321 VLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNF 1380
Query 860 RTILRDLTRLQPHN 873
IL +
Sbjct 1381 AIILERIEYCTQDP 1394
>sp|C0LGU5|Y5457_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At5g45780 OS=Arabidopsis thaliana OX=3702
GN=At5g45780 PE=1 SV=1
Length=614
Score = 246 bits (629), Expect = 8e-69, Method: Composition-based stats.
Identities = 80/328 (24%), Positives = 134/328 (41%), Gaps = 24/328 (7%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+ + + LG+G FG V G +VAV
Sbjct 273 HVQQDYEFEIGHLKRFSFREIQTATSNFSPKNILGQGGFGMVYKGYL-----PNGTVVAV 327
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K LK D ++ E++++ H ++++ G C E+ LV Y+P GS+ D
Sbjct 328 KRLK-DPIYTGEVQFQTEVEMIGLAVHRNLLRLFGFCMTPEER--MLVYPYMPNGSVADR 384
Query 990 LPRH-----SIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGD 1041
L + S+ + + A G+ YLH Q IHRD+ A N+LLD +GD
Sbjct 385 LRDNYGEKPSLDWNRRISIALGAARGLVYLHEQCNPKIIHRDVKAANILLDESFEAIVGD 444
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLAK + + + V + APE L + +DV+ FGV + EL+T
Sbjct 445 FGLAKLLDQRDSH--VTTAVRGTIGHIAPEYLSTGQSSEKTDVFGFGVLILELITGHKMI 502
Query 1102 QSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+ + ++ + R E+++R + D EV L C + + R
Sbjct 503 DQGNGQVRKGMILSWVRTLKAEKRFAEMVDRDLKGEFDDLVLEEVVELALLCTQPHPNLR 562
Query 1160 PTFENLIPILKTVHEK----YQGQAPSV 1183
P ++ +L+ + E+ Y+ +APSV
Sbjct 563 PRMSQVLKVLEGLVEQCEGGYEARAPSV 590
Score = 204 bits (519), Expect = 2e-54, Method: Composition-based stats.
Identities = 67/352 (19%), Positives = 112/352 (32%), Gaps = 65/352 (18%)
Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
+L + SF + + + LGQG VY+G L
Sbjct 284 HLKRFSFREIQTATSNFSPKNILGQGGFGMVYKGYLPNG--------------------- 322
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
V +K L + + F ++ H +L + G C+ E ++V Y+ +
Sbjct 323 ----TVVAVKRLKDPIYTGEVQFQTEVEMIGLAVHRNLLRLFGFCMTPEERMLVYPYMPN 378
Query 693 GPLDVWLRR---ERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLG 746
G + LR E+ + ++ +A A L YL + ++H +V NILL
Sbjct 379 GSVADRLRDNYGEKPSLDWNRRISIALGAARGLVYLHEQCNPKIIHRDVKAANILLDESF 438
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFG 801
A + D G+ R+ V I +APE L G + S D +GFG
Sbjct 439 EAI-------VGDFGLAKLLDQRDSHVTTAVRGTIGHIAPEYLSTGQS--SEKTDVFGFG 489
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP------------------EPSCPQLAT 843
+LE+ + Q K L + ++
Sbjct 490 VLILELITGHKMIDQGNGQVRKGMILSWVRTLKAEKRFAEMVDRDLKGEFDDLVLEEVVE 549
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895
L C P RP +L+ L L P + ++
Sbjct 550 LALLCTQPHPNLRPRMSQVLKVLEGLVEQCEGGYEARAPSVSRNYSNGHEEQ 601
>sp|Q9CAC3|CRK43_ARATH Cysteine-rich receptor-like protein kinase
43 OS=Arabidopsis thaliana OX=3702 GN=CRK43 PE=2 SV=2
Length=413
Score = 240 bits (612), Expect = 9e-69, Method: Composition-based stats.
Identities = 75/283 (27%), Positives = 111/283 (39%), Gaps = 18/283 (6%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
LGEG FG V G +AVK L Q ++ + E +L + H
Sbjct 50 FHPTHKLGEGGFGPVFKGRL-----PDGRDIAVKKLSQ-VSRQGKNEFVNEAKLLAKVQH 103
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMA 1012
+++ G C +K LV EYV SL L + I Q I G+
Sbjct 104 RNVVNLWGYCTHGDDK--LLVYEYVVNESLDKVLFKSNRKSEIDWKQRFEIITGIARGLL 161
Query 1013 YLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH IHRD+ A N+LLD + KI DFG+A+ E + R G + A
Sbjct 162 YLHEDAPNCIIHRDIKAGNILLDEKWVPKIADFGMARLYQEDVTHVNTRVAG--TNGYMA 219
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE + +DV+SFGV + EL++ +SS S L+ A R E+L
Sbjct 220 PEYVMHGVLSVKADVFSFGVLVLELVSGQKNSSFSMRHPDQTLLEWAFKLYKKGRTMEIL 279
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
++ + C + + RP+ + +L
Sbjct 280 DQDIAASADPDQVKLCVQIGLLCVQGDPHQRPSMRRVSLLLSR 322
Score = 220 bits (561), Expect = 8e-62, Method: Composition-based stats.
Identities = 72/357 (20%), Positives = 119/357 (33%), Gaps = 65/357 (18%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
K+ LG+G V++GRL GRD + +K L
Sbjct 46 ATKDFHPTHKLGEGGFGPVFKGRL-------------------PDGRD------IAVKKL 80
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR--E 702
F A L+++V H ++ + G C G + ++V EYV + LD L +
Sbjct 81 SQVSRQGKNEFVNEAKLLAKVQHRNVVNLWGYCTHGDDKLLVYEYVVNESLDKVLFKSNR 140
Query 703 RGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ + + + +A L YL ++H ++ NILL + K++D
Sbjct 141 KSEIDWKQRFEIITGIARGLLYLHEDAPNCIIHRDIKAGNILLDEKWVP-------KIAD 193
Query 760 PGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ V ++APE + G LS D + FG +LE+ +
Sbjct 194 FGMARLYQEDVTHVNTRVAGTNGYMAPEYVMHGV--LSVKADVFSFGVLVLELVSGQKNS 251
Query 815 LQSRSPSEKEHFYQ-----RQHRLPEPSCPQLA------------TLTSQCLTYEPTQRP 857
S ++ ++ R E +A + C+ +P QRP
Sbjct 252 SFSMRHPDQTLLEWAFKLYKKGRTMEILDQDIAASADPDQVKLCVQIGLLCVQGDPHQRP 311
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG----HFGK 910
S R + L+R H P S T G FG
Sbjct 312 SMRRVSLLLSRKPGHLEEPDHPGVPGSRYRRRTQRPSGAASLGTLSTTGSSTDSFGS 368
>sp|P0CY46|EGFR_APIME Epidermal growth factor receptor OS=Apis
mellifera OX=7460 GN=Egfr PE=2 SV=1
Length=1292
Score = 256 bits (655), Expect = 1e-68, Method: Composition-based stats.
Identities = 96/274 (35%), Positives = 137/274 (50%), Gaps = 20/274 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + VA+K L G + E I+ ++ H ++++
Sbjct 717 LGYGAFGNVYKGVWVPEGENVKIPVAIKVLHDGTGANTSKEFLDEAYIMASVEHPNLLQL 776
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
C + LV + +PLG L D++ R IG LL + QI GMAYL + +
Sbjct 777 LAVCMTS---QMMLVTQLMPLGCLLDFVRRFKDKIGSKALLNWCTQIARGMAYLEERRLV 833
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ VKI DFGLAK + E Y+ G P+ W A EC++ F +
Sbjct 834 HRDLAARNVLVQTPNCVKITDFGLAKLLDINEEQYKA-AGGKMPIKWLALECIQHRVFTH 892
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVW+FGVT++E+LT+ G + + ELLE+GERLP+P C
Sbjct 893 KSDVWAFGVTIWEVLTYG--------------GRPYENVPARNVPELLEKGERLPQPAIC 938
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+VY +M CW +A RP+F+ L +
Sbjct 939 TIDVYMIMIKCWMLDAESRPSFKELAEDFAKMSR 972
Score = 233 bits (593), Expect = 5e-61, Method: Composition-based stats.
Identities = 86/440 (20%), Positives = 164/440 (37%), Gaps = 60/440 (14%)
Query 475 WSTSHPYRLILTVAQRSQAPDGMQSLRLRKF-PIEQQDGAFVLEG---WGRSFPSVRELG 530
+ +P+++ PD L IE + +L G + +F V +
Sbjct 610 CTPEYPHKIF--------NPDSEPYCSLETAGLIENELQPAILAGVAVFALAFLVVAAII 661
Query 531 AALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEIT 590
+A ++ + + L R + NL++L + ++E+
Sbjct 662 MYFWRVRAKAKENTVKMTMAL-------TGLDDNEPLRPTGVKPNLAKLRI--IKEEEMR 712
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHH 649
+ LG G NVY+G EG ++ V +KVL D +
Sbjct 713 KGGILGYGAFGNVYKGVWVPEGENV--------------------KIPVAIKVLHDGTGA 752
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
+ + F + A +M+ V H +L + VC+ + ++VT+ + G L ++RR + +
Sbjct 753 NTSKEFLDEAYIMASVEHPNLLQLLAVCMTS-QMMLVTQLMPLGCLLDFVRRFKDKIGSK 811
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+ Q+A ++YLE + LVH ++ RN+L+ T +K++D G+
Sbjct 812 ALLNWCTQIARGMAYLEERRLVHRDLAARNVLV-------QTPNCVKITDFGLAKLLDIN 864
Query 770 EERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
EE+ + I WLA EC+ + D W FG T+ E+ G P ++
Sbjct 865 EEQYKAAGGKMPIKWLALECIQHRV--FTHKSDVWAFGVTIWEVLTYGGRPYENVPARNV 922
Query 824 EHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
++ RLP+P + + +C + RPSF+ + D ++ +
Sbjct 923 PELLEKGERLPQPAICTIDVYMIMIKCWMLDAESRPSFKELAEDFAKMSRDPGRYLAIKG 982
Query 882 PDSPASDPTVFHKRYLKKIR 901
Sbjct 983 DKYMRLPSYTLQDEKEMIRN 1002
>sp|Q54L00|LIMKA_DICDI Probable LIM domain-containing serine/threonine-protein
kinase DDB_G0287001 OS=Dictyostelium discoideum
OX=44689 GN=DDB_G0287001 PE=3 SV=1
Length=650
Score = 247 bits (630), Expect = 1e-68, Method: Composition-based stats.
Identities = 71/276 (26%), Positives = 116/276 (42%), Gaps = 30/276 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY--HEHII 960
+ G GKV Y + VA+K ++ + + +E+ I+ + H +
Sbjct 392 IASGASGKVYKGIYKGRD------VAIKVYSSENFCFNIEEFDREVTIMSLIDSDHPNFT 445
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
++ G Q +K L V E V GSLRD L + L A I M +LH+
Sbjct 446 RFYGA-NKQNKKYLFHVSELVKSGSLRDLLLDKEKPLAYFTQLSIASDIANAMKHLHSIG 504
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRDL + NVL+ D K+ DFG ++ V + + + +PE K +
Sbjct 505 VIHRDLKSLNVLITEDFTAKVIDFGTSRNV----DLAKQMTLNLGTSCYMSPELFKGNGY 560
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
DV++FG+ L+E++ + + + L+ +GER P
Sbjct 561 DETCDVYAFGIVLWEIIARKEP---------------YENINSWSIPVLVAKGERPTIPA 605
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
CP E L+K CW + RP+F+ + LK + E
Sbjct 606 DCPSEYSKLIKACWTDKPKKRPSFKEICDTLKKISE 641
Score = 182 bits (462), Expect = 1e-46, Method: Composition-based stats.
Identities = 56/298 (19%), Positives = 111/298 (37%), Gaps = 45/298 (15%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
+ + ++E+ + G VY+G + GRD V
Sbjct 378 YKELSKEEVAFGDVIASGASGKVYKG--------------------IYKGRD------VA 411
Query 641 LKVLDPSHHDI-ALAFYETASLMSQVS--HTHLAFVHGVCVRGPENIM-VTEYVEHGPLD 696
+KV + F ++MS + H + +G + + + V+E V+ G L
Sbjct 412 IKVYSSENFCFNIEEFDREVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSELVKSGSLR 471
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
L + + ++ +A +A+A+ +L + ++H ++ N+L+ K
Sbjct 472 DLLLDKEKPLAYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITE-------DFTAK 524
Query 757 LSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
+ D G ++ +++PE G N D + FG L EI E
Sbjct 525 VIDFGTSRNVDLAKQMTLNLGTSCYMSPELFKG--NGYDETCDVYAFGIVLWEIIARKE- 581
Query 814 PLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
P ++ + + R +P + + L C T +P +RPSF+ I L ++
Sbjct 582 PYENINSWSIPVLVAKGERPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTLKKI 639
>sp|Q9ZT07|RKS1_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase RKS1 OS=Arabidopsis thaliana OX=3702 GN=RKS1
PE=3 SV=3
Length=833
Score = 251 bits (641), Expect = 1e-68, Method: Composition-based stats.
Identities = 81/345 (23%), Positives = 140/345 (41%), Gaps = 25/345 (7%)
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFH------ 893
L T+ C+ E + R+ + + + + +F
Sbjct 451 MLLTVILFCVVRERRKSNRHRSSSANFAPVPFDFDESFRFEQDKARNRELPLFDLNTIVA 510
Query 894 -KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
LG G FG V +AVK L + G Q +K E+ ++
Sbjct 511 ATNNFSSQNKLGAGGFGPVYKGVLQNR-----MEIAVKRLSRNSG-QGMEEFKNEVKLIS 564
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQIC 1008
L H ++++ GCC + EK LV EY+P SL ++ R + + + + I
Sbjct 565 KLQHRNLVRILGCCVELEEK--MLVYEYLPNKSLDYFIFHEEQRAELDWPKRMEIVRGIA 622
Query 1009 EGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
G+ YLH IHRDL A N+LLD++ + KI DFG+A+ G++
Sbjct 623 RGILYLHQDSRLRIIHRDLKASNILLDSEMIPKISDFGMARIFG-GNQMEGCTSRVVGTF 681
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+ APE E +F SDV+SFGV + E++T +S + L+G T
Sbjct 682 GYMAPEYAMEGQFSIKSDVYSFGVLMLEIITGKKNSAF-HEESSNLVGHIWDLWENGEAT 740
Query 1126 ELLERG-ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
E+++ ++ ++ + + C + AS R +++ +L
Sbjct 741 EIIDNLMDQETYDEREVMKCIQIGLLCVQENASDRVDMSSVVIML 785
Score = 236 bits (603), Expect = 9e-64, Method: Composition-based stats.
Identities = 65/383 (17%), Positives = 117/383 (31%), Gaps = 61/383 (16%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
P P + +A R L L L+ + + LG G VY+G L+
Sbjct 479 PVPFDFDESFRFEQDKARNRELPLFDLNTIVAATNNFSSQNKLGAGGFGPVYKGVLQNR- 537
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672
+ + +K L + F L+S++ H +L
Sbjct 538 ------------------------MEIAVKRLSRNSGQGMEEFKNEVKLISKLQHRNLVR 573
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK-- 728
+ G CV E ++V EY+ + LD ++ E + W +M + + +A + YL
Sbjct 574 ILGCCVELEEKMLVYEYLPNKSLDYFIFHEEQRAELDWPKRMEIVRGIARGILYLHQDSR 633
Query 729 -NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWLAP 781
++H ++ NILL + K+SD G+ V ++AP
Sbjct 634 LRIIHRDLKASNILLDSEMIP-------KISDFGMARIFGGNQMEGCTSRVVGTFGYMAP 686
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS----------------EKEH 825
E G S D + FG +LEI + S E
Sbjct 687 EYAMEG--QFSIKSDVYSFGVLMLEIITGKKNSAFHEESSNLVGHIWDLWENGEATEIID 744
Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885
Q E + + C+ + R +++ L + +
Sbjct 745 NLMDQETYDEREVMKCIQIGLLCVQENASDRVDMSSVVIMLGHNATNLPNPKHPAFTSAR 804
Query 886 ASDPTVFHKRYLKKIRDLGEGHF 908
+ + + F
Sbjct 805 RRGGENGACLKGQTGISVNDVTF 827
>sp|P15208|INSR_MOUSE Insulin receptor OS=Mus musculus OX=10090
GN=Insr PE=1 SV=2
Length=1372
Score = 256 bits (655), Expect = 1e-68, Method: Composition-based stats.
Identities = 90/304 (30%), Positives = 146/304 (48%), Gaps = 29/304 (10%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGP 938
D + + +R+LG+G FG V G E VAVK +
Sbjct 996 FPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASL 1055
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------- 991
+ R + E +++ H+++ G +G+ +L +VME + G L+ +L
Sbjct 1056 RERIEFLNEASVMKGFTCHHVVRLLGVV-SKGQPTL-VVMELMAHGDLKSHLRSLRPDAE 1113
Query 992 ----RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
R L +++ +I +GMAYL+A+ ++HRDLAARN ++ +D VKIGDFG+ +
Sbjct 1114 NNPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRD 1173
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ E +YYR G PV W +PE LK+ F +SD+WSFGV L+E+ +
Sbjct 1174 IYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITS----------- 1221
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L ++ ++ + + G L PD CP + LM+ CW+ RPTF ++
Sbjct 1222 ---LAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVN 1278
Query 1168 ILKT 1171
+LK
Sbjct 1279 LLKD 1282
Score = 249 bits (636), Expect = 3e-66, Method: Composition-based stats.
Identities = 97/519 (19%), Positives = 179/519 (34%), Gaps = 82/519 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPF----VQAKLRPED----GLYLIHW-STSHPYRLILTVA 488
V+ + + D I GP+ V + E GL +++ S L +
Sbjct 830 VSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLC 889
Query 489 QRSQAPDGMQSLRLRKFPIEQ-----------------QDGAFVLEGWGRSFPSVREL-- 529
+ + RLR + F + + ++ ++
Sbjct 890 VSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIII 949
Query 530 --GAALQGCLLRAGDDCFSLRRCCLPQPGE----TSNLIIMRGARASPRTLNLSQLSFHR 583
+ + G LR+ P +SN + + P ++ +
Sbjct 950 GPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVP--DEWE 1007
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +++IT L LGQG+ VYEG + G+ E RV +K
Sbjct 1008 VPREKITLLRELGQGSFGMVYEGNAKDIIKGEA-------------------ETRVAVKT 1048
Query 644 LDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR- 701
++ S + F AS+M + H+ + GV +G ++V E + HG L LR
Sbjct 1049 VNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSL 1108
Query 702 --------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
R + + + ++A ++YL K VH ++ RN ++A
Sbjct 1109 RPDAENNPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAH-------DF 1161
Query 754 FIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+ D G+ + + + W++PE L G + + D W FG L EI
Sbjct 1162 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTASSDMWSFGVVLWEI 1219
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
E P Q S + F L P+ +L L C + P RP+F I+
Sbjct 1220 TSLAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNL 1279
Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
L + +V + + + + + + ++
Sbjct 1280 LKDDLHPSFPEVSFFYSEENKAPESEELEMEFEDMENVP 1318
>sp|Q9XEC8|CRK38_ARATH Cysteine-rich receptor-like protein kinase
38 OS=Arabidopsis thaliana OX=3702 GN=CRK38 PE=3 SV=1
Length=648
Score = 247 bits (630), Expect = 1e-68, Method: Composition-based stats.
Identities = 76/303 (25%), Positives = 118/303 (39%), Gaps = 19/303 (6%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933
D + + +G+G FG V GE +AVK L
Sbjct 316 QYDYGGQSKLRFDFRMILTATDDFSFENKIGQGGFGSVYKGKLPG-----GEEIAVKRLT 370
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--- 990
G Q ++ E+ +L L H +++K G C + E+ LV E+VP SL ++
Sbjct 371 RGSG-QGEIEFRNEVLLLTRLQHRNLVKLLGFCNEGDEE--ILVYEFVPNSSLDHFIFDE 427
Query 991 -PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
R + + + G+ YLH IHRDL A N+LLD K+ DFG+A+
Sbjct 428 EKRLLLTWDMRARIIEGVARGLVYLHEDSQLRIIHRDLKASNILLDAYMNPKVADFGMAR 487
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
R+ + APE ++ F +DV+SFGV L E++T S
Sbjct 488 LFNMDQTRAVTRK-VVGTFGYMAPEYVRNRTFSVKTDVYSFGVVLLEMITGR--SNKNYF 544
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ L L A +++ R ++ H+ C + S RPT +I
Sbjct 545 EALGLPAYAWKCWVAGEAASIIDHVLSRSRSNEI-MRFIHIGLLCVQENVSKRPTMSLVI 603
Query 1167 PIL 1169
L
Sbjct 604 QWL 606
Score = 233 bits (595), Expect = 5e-64, Method: Composition-based stats.
Identities = 49/244 (20%), Positives = 90/244 (37%), Gaps = 45/244 (18%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+ + + +GQG +VY+G+L
Sbjct 327 FDFRMILTATDDFSFENKIGQGGFGSVYKGKLPGGE------------------------ 362
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+ +K L + F L++++ H +L + G C G E I+V E+V + LD
Sbjct 363 -EIAVKRLTRGSGQGEIEFRNEVLLLTRLQHRNLVKLLGFCNEGDEEILVYEFVPNSSLD 421
Query 697 VWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGT 751
++ E + + W + + + +A L YL ++H ++ NILL
Sbjct 422 HFIFDEEKRLLLTWDMRARIIEGVARGLVYLHEDSQLRIIHRDLKASNILLD-------A 474
Query 752 SPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
K++D G+ + R V ++APE + + S D + FG LL
Sbjct 475 YMNPKVADFGMARLFNMDQTRAVTRKVVGTFGYMAPEYVRN--RTFSVKTDVYSFGVVLL 532
Query 806 EICF 809
E+
Sbjct 533 EMIT 536
>sp|Q9SXB8|Y1133_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g11330 OS=Arabidopsis thaliana OX=3702
GN=At1g11330 PE=1 SV=3
Length=842
Score = 251 bits (641), Expect = 1e-68, Method: Composition-based stats.
Identities = 81/280 (29%), Positives = 116/280 (41%), Gaps = 17/280 (6%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG V G+ +AVK L G Q E+ ++ L H ++
Sbjct 527 RNKLGQGGFGPVYKG-----KLPEGQEIAVKRLSRKSG-QGLEELMNEVVVISKLQHRNL 580
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015
+K GCC + E+ LV EY+P SL YL + + + IC G+ YLH
Sbjct 581 VKLLGCCIEGEER--MLVYEYMPKKSLDAYLFDPMKQKILDWKTRFNIMEGICRGLLYLH 638
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
IHRDL A N+LLD + KI DFGLA+ + R + +PE
Sbjct 639 RDSRLKIIHRDLKASNILLDENLNPKISDFGLARIFRANEDEANTRR-VVGTYGYMSPEY 697
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
E F SDV+S GV E+++ SS L L+ A L +
Sbjct 698 AMEGFFSEKSDVFSLGVIFLEIISGRRNSSSHKEENNLNLLAYAWKLWNDGEAASLADPA 757
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+K + H+ C + A+ RP N+I +L T
Sbjct 758 VFDKCFEKEIEKCVHIGLLCVQEVANDRPNVSNVIWMLTT 797
Score = 235 bits (599), Expect = 4e-63, Method: Composition-based stats.
Identities = 58/341 (17%), Positives = 108/341 (32%), Gaps = 62/341 (18%)
Query 521 RSFPSVRELGAALQGCLLRAGDDCFSL------RRCCLPQPGETSNLIIMRGARASPRTL 574
++ ++ + AA ++ C L +R + + A S
Sbjct 440 KTHSNLAVMIAAPVIGVMLIAAVCVLLACRKYKKRPAPAKDRSAELMFKRMEALTSDNES 499
Query 575 NLSQLSFHRVD----------QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
+Q+ + + + LGQG VY+G+L
Sbjct 500 ASNQIKLKELPLFEFQVLATSTDSFSLRNKLGQGGFGPVYKGKLPEGQ------------ 547
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+ +K L ++S++ H +L + G C+ G E +
Sbjct 548 -------------EIAVKRLSRKSGQGLEELMNEVVVISKLQHRNLVKLLGCCIEGEERM 594
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRN 739
+V EY+ LD +L + W + + + + L YL ++H ++ N
Sbjct 595 LVYEYMPKKSLDAYLFDPMKQKILDWKTRFNIMEGICRGLLYLHRDSRLKIIHRDLKASN 654
Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLST 793
ILL + K+SD G+ + E+ V +++PE G S
Sbjct 655 ILLDE-------NLNPKISDFGLARIFRANEDEANTRRVVGTYGYMSPEYAMEGF--FSE 705
Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834
D + G LEI G S + +L
Sbjct 706 KSDVFSLGVIFLEIIS-GRRNSSSHKEENNLNLLAYAWKLW 745
>sp|Q9M9E0|LRKS1_ARATH L-type lectin-domain containing receptor
kinase S.1 OS=Arabidopsis thaliana OX=3702 GN=LECRKS1 PE=1
SV=1
Length=656
Score = 247 bits (630), Expect = 1e-68, Method: Composition-based stats.
Identities = 91/432 (21%), Positives = 156/432 (36%), Gaps = 24/432 (6%)
Query 749 EGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG--ATLLE 806
+G + I +S VG+ R R P +A S + W
Sbjct 212 DGPNFQINVSVAPVGVLRPRRPTLTFRDPVIANYVSADMYAGFSASKTNWNEARRILAWS 271
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR-- 864
+ G + + L +A + C+ + I +
Sbjct 272 LSDTGALREINTTNLPVFFLENSSSSLSTG---AIAGIVIGCVVFVALIGFGGYLIWKKL 328
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
+ L P + + R LG G FGKV
Sbjct 329 MREEEEEEIEEWELEFWPHRFSYEELAAATEVFSNDRLLGSGGFGKVYRGIL-----SNN 383
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
+AVK + D Q + EI + L H+++++ +G C + E L LV +Y+P G
Sbjct 384 SEIAVKCVNHD-SKQGLREFMAEISSMGRLQHKNLVQMRGWCRRKNE--LMLVYDYMPNG 440
Query 985 SLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVK 1038
SL ++ P+ + + + EG+ YLH Q IHRD+ + N+LLD++ +
Sbjct 441 SLNQWIFDNPKEPMPWRRRRQVINDVAEGLNYLHHGWDQVVIHRDIKSSNILLDSEMRGR 500
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
+GDFGLAK G R + + APE ASDV+SFGV + E+++
Sbjct 501 LGDFGLAKLYEHGGAPNTTR--VVGTLGYLAPELASASAPTEASDVYSFGVVVLEVVSGR 558
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE-VYHLMKNCWETEAS 1157
+ + + L+ + R+ + + R E + L C + +
Sbjct 559 RPIEYAEEEDMVLVDWVRDLYGGGRVVDAADERVRSECETMEEVELLLKLGLACCHPDPA 618
Query 1158 FRPTFENLIPIL 1169
RP ++ +L
Sbjct 619 KRPNMREIVSLL 630
Score = 214 bits (545), Expect = 3e-57, Method: Composition-based stats.
Identities = 60/304 (20%), Positives = 106/304 (35%), Gaps = 60/304 (20%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ + LG G VY G L + +K +
Sbjct 357 ATEVFSNDRLLGSGGFGKVYRGILSNNS-------------------------EIAVKCV 391
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-R 703
+ F S M ++ H +L + G C R E ++V +Y+ +G L+ W+ +
Sbjct 392 NHDSKQGLREFMAEISSMGRLQHKNLVQMRGWCRRKNELMLVYDYMPNGSLNQWIFDNPK 451
Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+P + V +A L+YL ++ ++H ++ NILL +L D
Sbjct 452 EPMPWRRRRQVINDVAEGLNYLHHGWDQVVIHRDIKSSNILLDSEMRG-------RLGDF 504
Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ GA + V + +LAPE A + A D + FG +LE+
Sbjct 505 GLAKLYEHGGAPNTTRVVGTLGYLAPELASASAP--TEASDVYSFGVVVLEVVSGRRPIE 562
Query 816 QSRSPSEKEHFYQR----QHRLPEPSCPQ-------------LATLTSQCLTYEPTQRPS 858
+ + R R+ + + + L L C +P +RP+
Sbjct 563 YAEEEDMVLVDWVRDLYGGGRVVDAADERVRSECETMEEVELLLKLGLACCHPDPAKRPN 622
Query 859 FRTI 862
R I
Sbjct 623 MREI 626
>sp|Q9PVZ4|INSR_XENLA Insulin receptor OS=Xenopus laevis OX=8355
GN=insr PE=1 SV=1
Length=1362
Score = 256 bits (655), Expect = 1e-68, Method: Composition-based stats.
Identities = 92/313 (29%), Positives = 151/313 (48%), Gaps = 29/313 (9%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAV 929
+ + D + + +R+LG+G FG V G E+ VAV
Sbjct 986 YTSSNPEYLSASEVYIPDEWEVPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPEVRVAV 1045
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K + + R + E +++ H+++ G +G+ +L ++ME + G L+ Y
Sbjct 1046 KTVNESASLRERIEFLNEASVMKAFNCHHVVRLLGVV-SKGQPTL-VIMELMAHGDLKSY 1103
Query 990 LP-----------RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
L R + L +++ A +I +GMAYL+A+ ++HRDLAARN ++ +D VK
Sbjct 1104 LRSLRPDAENNPGRLAPTLKEIIQMAAEISDGMAYLNAKKFVHRDLAARNCMVADDYAVK 1163
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
IGDFG+ + + E +YYR G PV W +PE LK+ F SDVWSFGV L+E+ +
Sbjct 1164 IGDFGMTRDIYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTAFSDVWSFGVVLWEITS-- 1220
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
L ++ ++ + + G L P+ CP ++ LM+ CW+
Sbjct 1221 ------------LAEQPYQGLSNEQVLKFVMDGGSLDHPENCPPRLHSLMQMCWQYNPKM 1268
Query 1159 RPTFENLIPILKT 1171
RPTF +I +LK
Sbjct 1269 RPTFLEIIDMLKD 1281
Score = 254 bits (648), Expect = 1e-67, Method: Composition-based stats.
Identities = 86/398 (22%), Positives = 148/398 (37%), Gaps = 49/398 (12%)
Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQL---SFHRV 584
+ + G ++ L C + + + ++P L+ S++ V
Sbjct 948 NIVKIITGPIIAVFLLLIVLVYCVVQKKKDAEGPAGPLYTSSNPEYLSASEVYIPDEWEV 1007
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ +I L LGQG+ VYEG + G+P E+RV +K +
Sbjct 1008 PRDKINLLRELGQGSFGMVYEGIAKDIIKGEP-------------------EVRVAVKTV 1048
Query 645 DPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ S + F AS+M + H+ + GV +G +++ E + HG L +LR R
Sbjct 1049 NESASLRERIEFLNEASVMKAFNCHHVVRLLGVVSKGQPTLVIMELMAHGDLKSYLRSLR 1108
Query 704 GH---------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
+ + +A +++ ++YL K VH ++ RN ++A
Sbjct 1109 PDAENNPGRLAPTLKEIIQMAAEISDGMAYLNAKKFVHRDLAARNCMVA-------DDYA 1161
Query 755 IKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+K+ D G+ + + + W++PE L G + D W FG L EI
Sbjct 1162 VKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTAFSDVWSFGVVLWEIT 1219
Query 809 FDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
E P Q S + F L PE P+L +L C Y P RP+F I+ L
Sbjct 1220 SLAEQPYQGLSNEQVLKFVMDGGSLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDML 1279
Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
+ DV D T + + +
Sbjct 1280 KDDLRPSFQDVSFYYSDENKPPETDDLEIDFENMESTP 1317
>sp|Q9FPR3|EDR1_ARATH Serine/threonine-protein kinase EDR1 OS=Arabidopsis
thaliana OX=3702 GN=EDR1 PE=1 SV=1
Length=933
Score = 253 bits (645), Expect = 1e-68, Method: Composition-based stats.
Identities = 77/278 (28%), Positives = 124/278 (45%), Gaps = 30/278 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G +G+V + G VAVK L D + ++ E+ I+R L H +++
Sbjct 674 RIGLGSYGEVYHADWH------GTEVAVKKFLDQDFSGAALAEFRSEVRIMRRLRHPNVV 727
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018
+ G +L +V E++P GSL L R I + + A + GM LH
Sbjct 728 FFLGAVTRP--PNLSIVTEFLPRGSLYRILHRPKSHIDERRRIKMALDVAMGMNCLHTST 785
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL N+L+DN+ VK+GDFGL++ H + + W APE L+
Sbjct 786 PTIVHRDLKTPNLLVDNNWNVKVGDFGLSRL---KHNTFLSSKSTAGTPEWMAPEVLRNE 842
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
DV+SFGV L+EL T + G + + + + RL
Sbjct 843 PSNEKCDVYSFGVILWELATLRLPWR--------------GMNPMQVVGAVGFQNRRLEI 888
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
P + V ++ CW+T+ + RP+F L +LK ++
Sbjct 889 PKELDPVVGRIILECWQTDPNLRPSFAQLTEVLKPLNR 926
Score = 238 bits (607), Expect = 9e-64, Method: Composition-based stats.
Identities = 64/313 (20%), Positives = 116/313 (37%), Gaps = 45/313 (14%)
Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
R P+ L+ + + + ++ +G G+ VY
Sbjct 648 RNDPQVLDDADVGECEIPWNDLVIAERIGLGSYGEVYHADW------------------- 688
Query 628 VPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
G E+ V K LD F +M ++ H ++ F G R P +V
Sbjct 689 -----HGTEVAVK-KFLDQDFSGAALAEFRSEVRIMRRLRHPNVVFFLGAVTRPPNLSIV 742
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK--NLVHGNVCGRNILLAR 744
TE++ G L L R + H+ ++ +A +A ++ L +VH ++ N+L+
Sbjct 743 TEFLPRGSLYRILHRPKSHIDERRRIKMALDVAMGMNCLHTSTPTIVHRDLKTPNLLVDN 802
Query 745 LGLAEGTSPFIKLSDPGVGLGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800
+ +K+ D G+ LS + W+APE L + + D + F
Sbjct 803 -------NWNVKVGDFGLSRLKHNTFLSSKSTAGTPEWMAPEVLRNEPS--NEKCDVYSF 853
Query 801 GATLLEICFDGEAPLQSRSPSEK---EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857
G L E+ P + +P + F R+ +P+ P + + +C +P RP
Sbjct 854 GVILWELATL-RLPWRGMNPMQVVGAVGFQNRRLEIPKELDPVVGRIILECWQTDPNLRP 912
Query 858 SFRTILRDLTRLQ 870
SF + L L
Sbjct 913 SFAQLTEVLKPLN 925
>sp|Q25197|HTK7_HYDVU Putative insulin-like peptide receptor OS=Hydra
vulgaris OX=6087 GN=HTK7 PE=2 SV=1
Length=1477
Score = 257 bits (656), Expect = 1e-68, Method: Composition-based stats.
Identities = 89/320 (28%), Positives = 141/320 (44%), Gaps = 24/320 (8%)
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918
R + +D+ + ++ + + D ++ ++ IR+LG+G FG V
Sbjct 1006 HRKLEKDVQGVLYASVNPEYMNSKEVYIPDEWELNREKIELIRELGQGSFGMVFEGIAHG 1065
Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978
D VAVK + R QE I++ H++K G +VM
Sbjct 1066 IGDHAELRVAVKTTNENASIHDRIQILQEASIMKAFNCNHVVKLIGVVSQGQPT--FVVM 1123
Query 979 EYVPLGSLRDYLPRH-------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031
E + G L+ YL + ++ +I +GMAYL A+ ++H DLAARN ++
Sbjct 1124 ELMGRGDLKSYLKERRPDDGGIPLMRQEIYQMVAEIADGMAYLAARKFVHCDLAARNCMV 1183
Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091
+D VKIGDFG+A+ + E YYR P+ W APE LK+ F ASDVWSFGV L
Sbjct 1184 ASDFTVKIGDFGMARDIYE-RNYYRKDGKSLLPIRWMAPESLKDGIFSTASDVWSFGVVL 1242
Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
+E+ T L T ++ + L P+ C ++ M C
Sbjct 1243 WEICT--------------LASQPYQGKTNEQVLNFVLSNGHLDYPEGCDYQLREFMSLC 1288
Query 1152 WETEASFRPTFENLIPILKT 1171
W + RP+F ++ +L+
Sbjct 1289 WHRDPKMRPSFLEIVHVLEN 1308
Score = 241 bits (614), Expect = 2e-63, Method: Composition-based stats.
Identities = 94/446 (21%), Positives = 166/446 (37%), Gaps = 58/446 (13%)
Query 470 LYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVREL 529
Y+I S + + S A +G + + F + + L + + +
Sbjct 934 TYIIRKS--RFGNYVAKIRAISPAGNGSWTEEI-HFKVAE------LSVTKNNNQLIIGI 984
Query 530 GAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQL---SFHRVDQ 586
+A+ + F L L + E ++ A +P +N ++ +++
Sbjct 985 ISAVS--AVIVALLVFILLYMFLHRKLEKDVQGVL-YASVNPEYMNSKEVYIPDEWELNR 1041
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
++I + LGQG+ V+EG + G ELRV +K +
Sbjct 1042 EKIELIRELGQGSFGMVFEG--------------------IAHGIGDHAELRVAVKTTNE 1081
Query 647 SHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-- 703
+ + AS+M + H+ + GV +G +V E + G L +L+ R
Sbjct 1082 NASIHDRIQILQEASIMKAFNCNHVVKLIGVVSQGQPTFVVMELMGRGDLKSYLKERRPD 1141
Query 704 -GHVPM--AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G +P+ + ++A ++YL + VH ++ RN ++A + +K+ D
Sbjct 1142 DGGIPLMRQEIYQMVAEIADGMAYLAARKFVHCDLAARNCMVA-------SDFTVKIGDF 1194
Query 761 GVGLGALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ R + I W+APE L G STA D W FG L EIC P
Sbjct 1195 GMARDIYERNYYRKDGKSLLPIRWMAPESLKDGI--FSTASDVWSFGVVLWEICTLASQP 1252
Query 815 LQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
Q ++ + +F L PE QL S C +P RPSF I+ L
Sbjct 1253 YQGKTNEQVLNFVLSNGHLDYPEGCDYQLREFMSLCWHRDPKMRPSFLEIVHVLENEVDD 1312
Query 873 NLADVLTVNPDSPASDPTVFHKRYLK 898
+ V + + ++ K
Sbjct 1313 DFVMVSFYHEMKRKALEDIYMKSESY 1338
>sp|P0DV84|ALK_CANLF ALK tyrosine kinase receptor OS=Canis lupus
familiaris OX=9615 GN=ALK PE=3 SV=1
Length=1631
Score = 257 bits (656), Expect = 1e-68, Method: Composition-based stats.
Identities = 95/344 (28%), Positives = 142/344 (41%), Gaps = 34/344 (10%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
Q P ++ + + + S SD ++ + IR LG G FG+V
Sbjct 1089 QSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEG 1148
Query 915 CYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
+D + VAVK L C Q + E I+ H++I++ G +
Sbjct 1149 QVSGVPSDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRF 1208
Query 974 LQLVMEYVPLGSLRDYLPR--------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
+ L E + G L+ +L S+ + LL AQ I G YL H+IHRD+A
Sbjct 1209 ILL--ELMAGGDLKSFLRETRPRPNQPSSLAMLDLLHVAQDIACGCQYLEENHFIHRDIA 1266
Query 1026 ARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082
ARN LL + KIGDFG+A+ + YYR PV W PE E F +
Sbjct 1267 ARNCLLTCPGPGRVAKIGDFGMARDIYRA-SYYRKGGCAMLPVKWMPPEAFMEGIFTSKT 1325
Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
D WSFGV L+E+ + L + + + E + G R+ P CP
Sbjct 1326 DTWSFGVLLWEIFS--------------LGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPG 1371
Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
VY +M CW+ + RP F ++ ++ Y Q P V +
Sbjct 1372 PVYRIMTQCWQHQPEDRPNFAIILERIE-----YCTQDPDVINT 1410
Score = 253 bits (647), Expect = 2e-67, Method: Composition-based stats.
Identities = 80/343 (23%), Positives = 126/343 (37%), Gaps = 40/343 (12%)
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
S V +K IT + LG G VYEG++ G D PL
Sbjct 1117 TSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQV---------SGVPSDPSPL------- 1160
Query 635 QELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+V +K L L F A ++S+ +H ++ GV ++ ++ E + G
Sbjct 1161 ---QVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAGG 1217
Query 694 PLDVWLR--RERGHVPMAWKM----VVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
L +LR R R + P + M VAQ +A YLE + +H ++ RN LL
Sbjct 1218 DLKSFLRETRPRPNQPSSLAMLDLLHVAQDIACGCQYLEENHFIHRDIAARNCLLT---- 1273
Query 748 AEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFG 801
G K+ D G+ + + W+ PE G ++ D W FG
Sbjct 1274 CPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGI--FTSKTDTWSFG 1331
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSF 859
L EI G P S+S E F R+ P +CP + + +QC ++P RP+F
Sbjct 1332 VLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNF 1391
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902
IL + + + + +
Sbjct 1392 AIILERIEYCTQDPDVINTALPVEYGPLMEEEEKVPMRPQDPE 1434
>sp|O64776|Y1144_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61440 OS=Arabidopsis thaliana OX=3702
GN=At1g61440 PE=3 SV=2
Length=792
Score = 250 bits (638), Expect = 2e-68, Method: Composition-based stats.
Identities = 74/307 (24%), Positives = 119/307 (39%), Gaps = 17/307 (6%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
+ LG G FG V G +AVK L + Q +
Sbjct 465 FFEMNTIQTATSNFSLSNKLGHGGFGSVYKGKLQ-----DGREIAVKRLSS-SSEQGKQE 518
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ 999
+ EI ++ L H ++++ GCC + EK L+ E++ SL ++ R + +
Sbjct 519 FMNEIVLISKLQHRNLVRVLGCCVEGKEK--LLIYEFMKNKSLDTFVFGSRKRLELDWPK 576
Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
Q I G+ YLH IHRDL N+LLD KI DFGLA+ +G +Y
Sbjct 577 RFDIIQGIVRGLLYLHRDSRLRVIHRDLKVSNILLDEKMNPKISDFGLARLF-QGSQYQD 635
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIA 1115
+ + +PE F SD++SFGV L E+++ S S + L+
Sbjct 636 KTRRVVGTLGYMSPEYAWTGVFSEKSDIYSFGVLLLEIISGEKISRFSYGEEGKALLAYV 695
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
R LL++ + C + + + RP L+ +L T +
Sbjct 696 WECWCETRGVNLLDQALDDSSHPAEVGRCVQIGLLCVQHQPADRPNTLELLSMLTTTSDL 755
Query 1176 YQGQAPS 1182
+ P+
Sbjct 756 PLPKQPT 762
Score = 232 bits (591), Expect = 2e-62, Method: Composition-based stats.
Identities = 53/247 (21%), Positives = 95/247 (38%), Gaps = 45/247 (18%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L +++ + + + LG G +VY+G+L+
Sbjct 463 LEFFEMNTIQTATSNFSLSNKLGHGGFGSVYKGKLQDGR--------------------- 501
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ +K L S F L+S++ H +L V G CV G E +++ E++++
Sbjct 502 ----EIAVKRLSSSSEQGKQEFMNEIVLISKLQHRNLVRVLGCCVEGKEKLLIYEFMKNK 557
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748
LD ++ R + + W + + Q + L YL ++H ++ NILL
Sbjct 558 SLDTFVFGSRKRLELDWPKRFDIIQGIVRGLLYLHRDSRLRVIHRDLKVSNILLDEK--- 614
Query 749 EGTSPFIKLSDPGVGL----GALSREER--VERIPWLAPECLPGGANSLSTAMDKWGFGA 802
K+SD G+ + R V + +++PE G S D + FG
Sbjct 615 ----MNPKISDFGLARLFQGSQYQDKTRRVVGTLGYMSPEYAWTGV--FSEKSDIYSFGV 668
Query 803 TLLEICF 809
LLEI
Sbjct 669 LLLEIIS 675
>sp|A0JM20|TYRO3_XENTR Tyrosine-protein kinase receptor TYRO3
OS=Xenopus tropicalis OX=8364 GN=tyro3 PE=2 SV=1
Length=881
Score = 251 bits (642), Expect = 2e-68, Method: Composition-based stats.
Identities = 89/293 (30%), Positives = 134/293 (46%), Gaps = 28/293 (10%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG-PQHRSGWKQEIDIL 951
++ R LG+G FG V D T + VAVK LKA+ + +E +
Sbjct 499 QQQQFTLGRTLGKGEFGSVREAQLK-MEDDTMQKVAVKMLKAEIFCSSDIEEFLREAAFM 557
Query 952 RTLYHEHIIKYKGC-CEDQGEKSL---QLVMEYVPLGSLRDYLPRHSIGLA-------QL 1000
+ H ++ K G + + L +++ ++ G L +L IG L
Sbjct 558 KEFDHPNVCKLIGVSLRSRTKGRLPVPMVILPFMKHGDLHTFLLMSRIGEEPIALPIQTL 617
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+ F IC GM YL ++++IHRDLA RN +L+ D V + DFGL+K + G +YYR
Sbjct 618 VRFMIDICSGMEYLSSKNFIHRDLATRNCMLNEDMTVCVADFGLSKKIYSG-DYYRQGCA 676
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
PV W A E L + + SDVW+FGVTL+E++T +
Sbjct 677 SKLPVKWLALESLADNVYTVHSDVWAFGVTLWEIVTRGQ--------------TPYAGVE 722
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ L G RL +P C E+Y +M CW TE RP+F +L L+ +
Sbjct 723 NSEIYSYLTAGNRLKQPPDCLDELYEMMCQCWITEPKRRPSFVDLKRRLEAIW 775
Score = 223 bits (568), Expect = 6e-59, Method: Composition-based stats.
Identities = 71/314 (23%), Positives = 122/314 (39%), Gaps = 51/314 (16%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S+L + Q++ T LG+G +V E +L++E
Sbjct 491 SKLKDVLIQQQQFTLGRTLGKGEFGSVREAQLKMED---------------------DTM 529
Query 637 LRVVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTE 688
+V +K+L F A+ M + H ++ + GV +R P +++
Sbjct 530 QKVAVKMLKAEIFCSSDIEEFLREAAFMKEFDHPNVCKLIGVSLRSRTKGRLPVPMVILP 589
Query 689 YVEHGPLDVWLRRERG-----HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+++HG L +L R +P+ + + S + YL +KN +H ++ RN +L
Sbjct 590 FMKHGDLHTFLLMSRIGEEPIALPIQTLVRFMIDICSGMEYLSSKNFIHRDLATRNCMLN 649
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDK 797
+ ++D G+ S + + + WLA E L + D
Sbjct 650 E-------DMTVCVADFGLSKKIYSGDYYRQGCASKLPVKWLALESLADNV--YTVHSDV 700
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855
W FG TL EI G+ P SE + +RL P +L + QC EP +
Sbjct 701 WAFGVTLWEIVTRGQTPYAGVENSEIYSYLTAGNRLKQPPDCLDELYEMMCQCWITEPKR 760
Query 856 RPSFRTILRDLTRL 869
RPSF + R L +
Sbjct 761 RPSFVDLKRRLEAI 774
>sp|Q10656|EGL15_CAEEL Myoblast growth factor receptor egl-15
OS=Caenorhabditis elegans OX=6239 GN=egl-15 PE=1 SV=1
Length=1040
Score = 254 bits (648), Expect = 2e-68, Method: Composition-based stats.
Identities = 99/337 (29%), Positives = 153/337 (45%), Gaps = 52/337 (15%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+ N + + + + + L + LGEG FG+V Y T + VAV
Sbjct 613 KRMNSENTVLSEYEVDSDPVWEVERSKLSLVHMLGEGAFGEVWKATYKETENNE-IAVAV 671
Query 930 KALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
K LK + E++ + + HE++++ GCC G L +V+E G+LRD
Sbjct 672 KKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCT--GAGPLYVVVELCKHGNLRD 729
Query 989 YLPRHSIGLA---------------------------------QLLLFAQQICEGMAYLH 1015
+L H L+ FA Q+ +GM +L
Sbjct 730 FLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLA 789
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
++ IHRDLAARNVL+ + ++KI DFGL++ V ++YYR R +G P+ W A E L
Sbjct 790 SKKIIHRDLAARNVLVGDGHVLKISDFGLSRDV-HCNDYYRKRGNGRLPIKWMALEALDS 848
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ SDVWS+GV L+E++T L G + + L L+ G R+
Sbjct 849 NVYTVESDVWSYGVLLWEIMT--------------LGGTPYPTIAMPELYANLKEGYRME 894
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P CP EVYHLM +CW + RP+F+ ++ L +
Sbjct 895 PPHLCPQEVYHLMCSCWREKLEERPSFKTIVDYLDWM 931
Score = 215 bits (547), Expect = 8e-56, Method: Composition-based stats.
Identities = 70/364 (19%), Positives = 126/364 (35%), Gaps = 76/364 (21%)
Query 555 PGETSNLIIMRGARASPRTLNLSQLSF-----HRVDQKEITQLSHLGQGTRTNVYEGRLR 609
P + R + LS+ V++ +++ + LG+G V++ +
Sbjct 601 PITKKEAARKQRKRMNSENTVLSEYEVDSDPVWEVERSKLSLVHMLGEGAFGEVWKATYK 660
Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SH 667
E+ V +K L S H+ L + H
Sbjct 661 ET---------------------ENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEH 699
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH---------------------- 705
++ + G C +V E +HG L +LR R
Sbjct 700 ENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASD 759
Query 706 -------VPMAWK--MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+ + + A Q+A +++L +K ++H ++ RN+L+ G +K
Sbjct 760 KDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLV-------GDGHVLK 812
Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+SD G+ + +R I W+A E L + D W +G L EI
Sbjct 813 ISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNV--YTVESDVWSYGVLLWEIMTL 870
Query 811 GEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTR 868
G P + + E + +R+ P CPQ + L C + +RPSF+TI+ L
Sbjct 871 GGTPYPTIAMPELYANLKEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIVDYLDW 930
Query 869 LQPH 872
+
Sbjct 931 MLTM 934
>sp|Q0D5R2|CRK10_ORYSJ Cysteine-rich receptor-like protein kinase
10 OS=Oryza sativa subsp. japonica OX=39947 GN=CRK10 PE=2
SV=1
Length=645
Score = 246 bits (628), Expect = 2e-68, Method: Composition-based stats.
Identities = 78/326 (24%), Positives = 125/326 (38%), Gaps = 17/326 (5%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
R L T + ++ + + + LGEG FG V
Sbjct 305 CSTSWRRRRLARKTLRPKSSEDEMQSFASLVLDLQTLRTATDNFSEHKRLGEGGFGVVYK 364
Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
+ G+ +AVK L A Q K E+ ++ L H ++++ G C ++ EK
Sbjct 365 G-----DLPEGQEIAVKRL-AQTSRQGIEELKTELLLVAKLNHNNLVRLIGVCLEENEKI 418
Query 974 LQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAA 1026
L EY+P SL L + Q I G+ YLH +HRDL A
Sbjct 419 LA--YEYMPNRSLDTILFDAERIKELDWGQRFKIINGIARGLQYLHEDSQLKIVHRDLKA 476
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
NVLLD+ KI DFGLAK + +PE ++ DV+S
Sbjct 477 SNVLLDSAYNPKISDFGLAKIFERDQSQVITHRIA-GTYGYMSPEYAMRGQYSMKLDVYS 535
Query 1087 FGVTLYELLTHCDSSQSPPTKF-LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
FGV + E++T + S + ++LI + T + EL++ P +
Sbjct 536 FGVLVLEIITGRRNFGSYGSDHVVDLIYVTWEHWTSDKAIELIDPSLGNHYPVDKVLKCI 595
Query 1146 HLMKNCWETEASFRPTFENLIPILKT 1171
H+ C + + + RP + +L +
Sbjct 596 HIGLLCVQPKPADRPLMSAVNAMLSS 621
Score = 215 bits (548), Expect = 7e-58, Method: Composition-based stats.
Identities = 53/316 (17%), Positives = 100/316 (32%), Gaps = 62/316 (20%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
L R ++ LG+G VY+G L
Sbjct 337 DLQTLRTATDNFSEHKRLGEGGFGVVYKGDLPEGQ------------------------- 371
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+ +K L + L+++++H +L + GVC+ E I+ EY+ + LD
Sbjct 372 EIAVKRLAQTSRQGIEELKTELLLVAKLNHNNLVRLIGVCLEENEKILAYEYMPNRSLDT 431
Query 698 WLRRER--GHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752
L + + + +A L YL +VH ++ N+LL ++
Sbjct 432 ILFDAERIKELDWGQRFKIINGIARGLQYLHEDSQLKIVHRDLKASNVLLD-------SA 484
Query 753 PFIKLSDPGVGLGALSREERV------ERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
K+SD G+ + +V +++PE G S +D + FG +LE
Sbjct 485 YNPKISDFGLAKIFERDQSQVITHRIAGTYGYMSPEYAMRG--QYSMKLDVYSFGVLVLE 542
Query 807 ICFDGE---------------APLQSRSPSEKEHFYQR--QHRLPEPSCPQLATLTSQCL 849
I + + + + P + + C+
Sbjct 543 IITGRRNFGSYGSDHVVDLIYVTWEHWTSDKAIELIDPSLGNHYPVDKVLKCIHIGLLCV 602
Query 850 TYEPTQRPSFRTILRD 865
+P RP +
Sbjct 603 QPKPADRPLMSAVNAM 618
>sp|P15127|INSR_RAT Insulin receptor OS=Rattus norvegicus OX=10116
GN=Insr PE=1 SV=1
Length=1383
Score = 256 bits (654), Expect = 2e-68, Method: Composition-based stats.
Identities = 90/304 (30%), Positives = 146/304 (48%), Gaps = 29/304 (10%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGP 938
D + + +R+LG+G FG V G E VAVK +
Sbjct 1007 FPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEVETRVAVKTVNESASL 1066
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------- 991
+ R + E +++ H+++ G +G+ +L +VME + G L+ +L
Sbjct 1067 RERIEFLNEASVMKGFTCHHVVRLLGVV-SKGQPTL-VVMELMAHGDLKSHLRSLRPDAE 1124
Query 992 ----RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
R L +++ +I +GMAYL+A+ ++HRDLAARN ++ +D VKIGDFG+ +
Sbjct 1125 NNPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRD 1184
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ E +YYR G PV W +PE LK+ F +SD+WSFGV L+E+ +
Sbjct 1185 IYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITS----------- 1232
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L ++ ++ + + G L PD CP + LM+ CW+ RPTF ++
Sbjct 1233 ---LAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVN 1289
Query 1168 ILKT 1171
+LK
Sbjct 1290 LLKD 1293
Score = 250 bits (639), Expect = 1e-66, Method: Composition-based stats.
Identities = 97/519 (19%), Positives = 179/519 (34%), Gaps = 82/519 (16%)
Query 438 VAPPRLVMSIRDGIHGPLLEPF----VQAKLRPED----GLYLIHW-STSHPYRLILTVA 488
V+ + + D I GP+ V + E GL +++ S L +
Sbjct 841 VSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLC 900
Query 489 QRSQAPDGMQSLRLRKFPIEQ-----------------QDGAFVLEGWGRSFPSVREL-- 529
+ + RLR + F + + ++ ++
Sbjct 901 VSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIII 960
Query 530 --GAALQGCLLRAGDDCFSLRRCCLPQPGE----TSNLIIMRGARASPRTLNLSQLSFHR 583
+ + G LR+ P +SN + + P ++ +
Sbjct 961 GPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVP--DEWE 1018
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V +++IT L LGQG+ VYEG + G+ E RV +K
Sbjct 1019 VPREKITLLRELGQGSFGMVYEGNAKDIIKGEV-------------------ETRVAVKT 1059
Query 644 LDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR- 701
++ S + F AS+M + H+ + GV +G ++V E + HG L LR
Sbjct 1060 VNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSL 1119
Query 702 --------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
R + + + ++A ++YL K VH ++ RN ++A
Sbjct 1120 RPDAENNPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAH-------DF 1172
Query 754 FIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+ D G+ + + + W++PE L G + + D W FG L EI
Sbjct 1173 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTASSDMWSFGVVLWEI 1230
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
E P Q S + F L P+ +L L C + P RP+F I+
Sbjct 1231 TSLAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNL 1290
Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
L + +V + + + + + + ++
Sbjct 1291 LKDDLHPSFPEVSFFYSEENKAPESEELEMEFEDMENVP 1329
>sp|Q95ZV7|DDRB_CAEEL Discoidin domain-containing receptor tyrosine
kinase B OS=Caenorhabditis elegans OX=6239 GN=ddr-2 PE=1
SV=1
Length=797
Score = 249 bits (637), Expect = 2e-68, Method: Composition-based stats.
Identities = 89/276 (32%), Positives = 145/276 (53%), Gaps = 18/276 (7%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+ +G+G FG+V L + VAVK L + +EI +L +L H +
Sbjct 529 CVSRIGQGEFGEVDLCQLE------NRKVAVKKL-HGISQADEFSFHREIRVLGSLKHPN 581
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQ 1017
+++ G C Q K + +MEY+ G L+ Y+ ++ I +Q + Q+ G+AYL +
Sbjct 582 VVEVVGVCTIQ--KPILCIMEYMENGDLKSYILKNPTIQTSQCISICTQLAAGLAYLESC 639
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+++HRD+AARN L+D + VKI DFG+A+++ EYY+V P+ W A E L K
Sbjct 640 NFVHRDIAARNCLVDGEGNVKIADFGMARSLY-SQEYYKVEGKFVLPIRWMAWEALLLGK 698
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
F ASDVW FGVT++E+ + C +++ Q + L ++ L RP
Sbjct 699 FSTASDVWGFGVTMWEIFSLCSEKPYSDMTDDDVVENLQSMSSTGSLKQV------LSRP 752
Query 1138 DKCPCEVY-HLMKNCWETEASFRPTFENLIPILKTV 1172
CP ++Y + CW E+S RP+FEN+ L+++
Sbjct 753 RMCPSKLYNEQILPCWNYESSRRPSFENVHLHLQSL 788
Score = 214 bits (544), Expect = 2e-56, Method: Composition-based stats.
Identities = 70/316 (22%), Positives = 118/316 (37%), Gaps = 53/316 (17%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
+ + + ++ +S +GQG V +L + +V
Sbjct 518 TLPEIARDKLICVSRIGQGEFGEVDLCQL--------------------------ENRKV 551
Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+K L +F+ ++ + H ++ V GVC + + EY+E+G L ++
Sbjct 552 AVKKLHGISQADEFSFHREIRVLGSLKHPNVVEVVGVCTIQKPILCIMEYMENGDLKSYI 611
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ + + + + QLA+ L+YLE+ N VH ++ RN L+ G +K++D
Sbjct 612 LKN-PTIQTSQCISICTQLAAGLAYLESCNFVHRDIAARNCLVDGEG-------NVKIAD 663
Query 760 PGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF-DGE 812
G+ S+E V I W+A E L G STA D WGFG T+ EI E
Sbjct 664 FGMARSLYSQEYYKVEGKFVLPIRWMAWEALLLG--KFSTASDVWGFGVTMWEIFSLCSE 721
Query 813 APLQSRSPSEKEH----------FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
P + + Q R C YE ++RPSF +
Sbjct 722 KPYSDMTDDDVVENLQSMSSTGSLKQVLSRPRMCPSKLYNEQILPCWNYESSRRPSFENV 781
Query 863 LRDLTRLQPHNLADVL 878
L L +
Sbjct 782 HLHLQSLVHTSPHIHF 797
>sp|O65482|CRK23_ARATH Putative cysteine-rich receptor-like protein
kinase 23 OS=Arabidopsis thaliana OX=3702 GN=CRK23 PE=2
SV=1
Length=830
Score = 250 bits (639), Expect = 2e-68, Method: Composition-based stats.
Identities = 72/282 (26%), Positives = 116/282 (41%), Gaps = 18/282 (6%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
I LG+G FG+V + +G VAVK L G R ++ E+ ++ L H +
Sbjct 510 PINKLGQGGFGEVYKGTF-----PSGVQVAVKRLSKTSGQGERE-FENEVVVVAKLQHRN 563
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYL 1014
+++ G C + EK LV E+V SL +L + + + I G+ YL
Sbjct 564 LVRLLGYCLEGEEK--ILVYEFVHNKSLDYFLFDTTMKRQLDWTRRYKIIGGIARGILYL 621
Query 1015 HAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
H IHRDL A N+LLD D K+ DFG+A+ R + APE
Sbjct 622 HQDSRLTIIHRDLKAGNILLDADMNPKVADFGMARIFGMDQTEANTRR-VVGTYGYMAPE 680
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLTELLE 1129
+F SDV+SFGV ++E+++ +S L+ + +L++
Sbjct 681 YAMYGQFSMKSDVYSFGVLVFEIISGMKNSSLYQMDDSVSNLVTYTWRLWSNGSQLDLVD 740
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
H+ C + + RP ++ +L T
Sbjct 741 PSFGDNYQTHDITRCIHIALLCVQEDVDDRPNMSAIVQMLTT 782
Score = 230 bits (587), Expect = 1e-61, Method: Composition-based stats.
Identities = 56/324 (17%), Positives = 104/324 (32%), Gaps = 65/324 (20%)
Query 573 TLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
T Q F + ++ LGQG VY+G
Sbjct 490 TAGSLQFDFKAIVAATNNFLPINKLGQGGFGEVYKGT----------------------- 526
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
++V +K L + F +++++ H +L + G C+ G E I+V E+V
Sbjct 527 --FPSGVQVAVKRLSKTSGQGEREFENEVVVVAKLQHRNLVRLLGYCLEGEEKILVYEFV 584
Query 691 EHGPLDVWLRRE--RGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745
+ LD +L + + + + +A + YL + ++H ++ NILL
Sbjct 585 HNKSLDYFLFDTTMKRQLDWTRRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNILLD-- 642
Query 746 GLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
K++D G+ + V ++APE G S D +
Sbjct 643 -----ADMNPKVADFGMARIFGMDQTEANTRRVVGTYGYMAPEYAMYG--QFSMKSDVYS 695
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC------PQLAT---------- 843
FG + EI + + + RL P
Sbjct 696 FGVLVFEIISGMKNSSLYQMDDSVSNLVTYTWRLWSNGSQLDLVDPSFGDNYQTHDITRC 755
Query 844 --LTSQCLTYEPTQRPSFRTILRD 865
+ C+ + RP+ I++
Sbjct 756 IHIALLCVQEDVDDRPNMSAIVQM 779
>sp|Q8W4G6|CRK15_ARATH Cysteine-rich receptor-like protein kinase
15 OS=Arabidopsis thaliana OX=3702 GN=CRK15 PE=2 SV=2
Length=627
Score = 246 bits (627), Expect = 2e-68, Method: Composition-based stats.
Identities = 71/294 (24%), Positives = 118/294 (40%), Gaps = 17/294 (6%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
+ +G+G FG+V + G VAVK L G Q + +K
Sbjct 326 DYRMIRAATNKFSENNKIGQGGFGEVYKGTF-----SNGTEVAVKRLSKSSG-QGDTEFK 379
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLL 1001
E+ ++ L H ++++ G GE+ LV EY+P SL +L ++ + +
Sbjct 380 NEVVVVAKLQHRNLVRLLGFSIGGGER--ILVYEYMPNKSLDYFLFDPAKQNQLDWTRRY 437
Query 1002 LFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
I G+ YLH IHRDL A N+LLD D K+ DFGLA+
Sbjct 438 KVIGGIARGILYLHQDSRLTIIHRDLKASNILLDADMNPKLADFGLARIFGMDQTQENTS 497
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQG 1117
+ APE +F SDV+SFGV + E+++ ++S +L+ A
Sbjct 498 R-IVGTFGYMAPEYAIHGQFSVKSDVYSFGVLVLEIISGKKNNSFYETDGAHDLVTHAWR 556
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ +L++ H+ C + + + RP + +L +
Sbjct 557 LWSNGTALDLVDPIIIDNCQKSEVVRCIHICLLCVQEDPAERPILSTIFMMLTS 610
Score = 236 bits (601), Expect = 6e-65, Method: Composition-based stats.
Identities = 72/376 (19%), Positives = 120/376 (32%), Gaps = 70/376 (19%)
Query 519 WGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQ 578
W + V + L LL CF+ R + N G + +L L
Sbjct 273 WNSNVLVVAIVLTILVAALLLIAGYCFAKRVK-----NSSDNAPAFDGDDITTESLQL-D 326
Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
R + ++ + +GQG VY+G
Sbjct 327 YRMIRAATNKFSENNKIGQGGFGEVYKGT-------------------------FSNGTE 361
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V +K L S F +++++ H +L + G + G E I+V EY+ + LD +
Sbjct 362 VAVKRLSKSSGQGDTEFKNEVVVVAKLQHRNLVRLLGFSIGGGERILVYEYMPNKSLDYF 421
Query 699 LRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSP 753
L + W + V +A + YL + ++H ++ NILL
Sbjct 422 LFDPAKQNQLDWTRRYKVIGGIARGILYLHQDSRLTIIHRDLKASNILLD-------ADM 474
Query 754 FIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
KL+D G+ + V ++APE G S D + FG +LEI
Sbjct 475 NPKLADFGLARIFGMDQTQENTSRIVGTFGYMAPEYAIHG--QFSVKSDVYSFGVLVLEI 532
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLP------EPSCPQLAT------------LTSQCL 849
G+ RL + P + + C+
Sbjct 533 IS-GKKNNSFYETDGAHDLVTHAWRLWSNGTALDLVDPIIIDNCQKSEVVRCIHICLLCV 591
Query 850 TYEPTQRPSFRTILRD 865
+P +RP TI
Sbjct 592 QEDPAERPILSTIFMM 607
>sp|Q41328|PTI1_SOLLC Pto-interacting protein 1 OS=Solanum lycopersicum
OX=4081 GN=PTI1 PE=1 SV=2
Length=354
Score = 237 bits (604), Expect = 2e-68, Method: Composition-based stats.
Identities = 75/284 (26%), Positives = 124/284 (44%), Gaps = 24/284 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG +G+V +G A+K L D Q + ++ ++ L E++++
Sbjct 74 IGEGSYGRVYHGVLK-----SGRAAAIKKL--DSSKQPDREFLAQVSMVSRLKDENVVEL 126
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------IGLAQLLLFAQQICEGMA 1012
G C D G + L EY P GSL D L + AQ + A +G+
Sbjct 127 LGYCVDGGFR--VLAYEYAPNGSLHDILHGRKGVKGAQPGPVLSWAQRVKIAVGAAKGLE 184
Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH + H IHRD+ + N+LL +D + KI DF L+ P+ ++A
Sbjct 185 YLHEKAQPHIIHRDIKSSNILLFDDDVAKIADFDLSNQAPD-MAARLHSTRVLGTFGYHA 243
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE + SDV+SFGV L ELLT + P L+ A +++ ++ + +
Sbjct 244 PEYAMTGQLSSKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVKQCV 303
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ P K ++ + C + EA FRP ++ L+ +
Sbjct 304 DARLNTDYPPKAIAKMAAVAALCVQYEADFRPNMSIVVKALQPL 347
Score = 209 bits (531), Expect = 2e-58, Method: Composition-based stats.
Identities = 59/312 (19%), Positives = 106/312 (34%), Gaps = 59/312 (19%)
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLS-------HLGQGTRTNVYEGRL 608
G A+ +T+N+ ++ + E+ ++ +G+G+ VY G L
Sbjct 28 GNNGGQRATESAQRETQTVNIQPIAVPSIAVDELKDITDNFGSKALIGEGSYGRVYHGVL 87
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHT 668
+ +K LD S F S++S++
Sbjct 88 KSGR-------------------------AAAIKKLD-SSKQPDREFLAQVSMVSRLKDE 121
Query 669 HLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG--------HVPMAWKMVVAQQLAS 720
++ + G CV G ++ EY +G L L +G + A ++ +A A
Sbjct 122 NVVELLGYCVDGGFRVLAYEYAPNGSLHDILHGRKGVKGAQPGPVLSWAQRVKIAVGAAK 181
Query 721 ALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG------LGALSREE 771
L YL K +++H ++ NILL K++D + L
Sbjct 182 GLEYLHEKAQPHIIHRDIKSSNILL-------FDDDVAKIADFDLSNQAPDMAARLHSTR 234
Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
+ + APE G LS+ D + FG LLE+ + + ++
Sbjct 235 VLGTFGYHAPEYAMTG--QLSSKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATP 292
Query 832 RLPEPSCPQLAT 843
RL E Q
Sbjct 293 RLSEDKVKQCVD 304
>sp|O65468|CRK8_ARATH Cysteine-rich receptor-like protein kinase
8 OS=Arabidopsis thaliana OX=3702 GN=CRK8 PE=3 SV=2
Length=676
Score = 246 bits (629), Expect = 3e-68, Method: Composition-based stats.
Identities = 74/279 (27%), Positives = 118/279 (42%), Gaps = 17/279 (6%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G FG+V + G+ VAVK L + Q + +K E+ ++ L H +++
Sbjct 357 NKIGRGGFGEVYKGTF-----SNGKEVAVKRLSKN-SRQGEAEFKTEVVVVAKLQHRNLV 410
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016
+ G QGE+ + LV EY+P SL L + + Q I G+ YLH
Sbjct 411 RLLG-FSLQGEERI-LVYEYMPNKSLDCLLFDPTKQTQLDWMQRYNIIGGIARGILYLHQ 468
Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRDL A N+LLD D KI DFG+A+ + APE
Sbjct 469 DSRLTIIHRDLKASNILLDADINPKIADFGMARIFGLDQTQDNTSR-IVGTYGYMAPEYA 527
Query 1074 KEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+F SDV+SFGV + E+++ +SS +L+ T +L++
Sbjct 528 MHGQFSMKSDVYSFGVLVLEIISGRKNSSFDESDGAQDLLTHTWRLWTNRTALDLVDPLI 587
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ H+ C + + + RPT + +L +
Sbjct 588 ANNCQNSEVVRCIHIGLLCVQEDPAKRPTISTVFMMLTS 626
Score = 230 bits (587), Expect = 9e-63, Method: Composition-based stats.
Identities = 62/353 (18%), Positives = 118/353 (33%), Gaps = 67/353 (19%)
Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRT 601
CF +R + +T++ + A+ +L L + + + + +G+G
Sbjct 309 GYCFLAQR--TKKTFDTASASEVGDDMATADSLQL-DYRTIQTATNDFAESNKIGRGGFG 365
Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL 661
VY+G V +K L + F +
Sbjct 366 EVYKGTFSNGK-------------------------EVAVKRLSKNSRQGEAEFKTEVVV 400
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLA 719
++++ H +L + G ++G E I+V EY+ + LD L + W + + +A
Sbjct 401 VAKLQHRNLVRLLGFSLQGEERILVYEYMPNKSLDCLLFDPTKQTQLDWMQRYNIIGGIA 460
Query 720 SALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSRE 770
+ YL + ++H ++ NILL K++D G+ +
Sbjct 461 RGILYLHQDSRLTIIHRDLKASNILLD-------ADINPKIADFGMARIFGLDQTQDNTS 513
Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
V ++APE G S D + FG +LEI G +
Sbjct 514 RIVGTYGYMAPEYAMHG--QFSMKSDVYSFGVLVLEIIS-GRKNSSFDESDGAQDLLTHT 570
Query 831 HRLP------EPSCPQLAT------------LTSQCLTYEPTQRPSFRTILRD 865
RL + P +A + C+ +P +RP+ T+
Sbjct 571 WRLWTNRTALDLVDPLIANNCQNSEVVRCIHIGLLCVQEDPAKRPTISTVFMM 623
>sp|Q9SA25|WAKLG_ARATH Wall-associated receptor kinase-like 8
OS=Arabidopsis thaliana OX=3702 GN=WAKL8 PE=2 SV=1
Length=720
Score = 247 bits (631), Expect = 3e-68, Method: Composition-based stats.
Identities = 76/284 (27%), Positives = 129/284 (45%), Gaps = 18/284 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G G V + G +VAVK KA ++ + EI +L + H +++K
Sbjct 396 LGQGGQGTVYKGMLE-----DGMIVAVKKSKA-LKEENLEEFINEIILLSQINHRNVVKI 449
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGMAYLHAQ- 1017
GCC + E + LV E++P +L D+L + L A ++ + ++YLH+
Sbjct 450 LGCCLE-TEVPI-LVYEFIPNRNLFDHLHNPSEDFPMSWEVRLCIACEVADALSYLHSAV 507
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
HRD+ + N+LLD K+ DFG++++V + + + + PE L+
Sbjct 508 SIPIYHRDVKSTNILLDEKHRAKVSDFGISRSVAIDDTH--LTTIVQGTIGYVDPEYLQS 565
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ-MTVLRLTELLERGERL 1134
F SDV+SFGV L ELLT + + ++G + M RL E+L+ +
Sbjct 566 NHFTGKSDVYSFGVLLIELLTGEKPVSLLRRQEVRMLGAYFLEAMRNDRLHEILDARIKE 625
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
+ V L + C + RPT ++ L + K +G
Sbjct 626 ECDREEVLAVAKLARRCLSLNSEHRPTMRDVFIELDRMQSKRKG 669
Score = 219 bits (559), Expect = 8e-59, Method: Composition-based stats.
Identities = 70/349 (20%), Positives = 118/349 (34%), Gaps = 63/349 (18%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
LGQG + VY+G L + V +K
Sbjct 386 ATDRFNASRILGQGGQGTVYKGMLEDG-------------------------MIVAVKKS 420
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ F L+SQ++H ++ + G C+ I+V E++ + L L
Sbjct 421 KALKEENLEEFINEIILLSQINHRNVVKILGCCLETEVPILVYEFIPNRNLFDHLHNPSE 480
Query 705 HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
PM+W ++ +A ++A ALSYL + + H +V NILL K+SD
Sbjct 481 DFPMSWEVRLCIACEVADALSYLHSAVSIPIYHRDVKSTNILLDEK-------HRAKVSD 533
Query 760 PGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ + + I ++ PE L +N + D + FG L+E+ GE P
Sbjct 534 FGISRSVAIDDTHLTTIVQGTIGYVDPEYLQ--SNHFTGKSDVYSFGVLLIELL-TGEKP 590
Query 815 LQSRSPSEKEHFY------QRQHRLPEPSCPQL------------ATLTSQCLTYEPTQR 856
+ E R RL E ++ A L +CL+ R
Sbjct 591 VSLLRRQEVRMLGAYFLEAMRNDRLHEILDARIKEECDREEVLAVAKLARRCLSLNSEHR 650
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
P+ R + +L R+Q + + +
Sbjct 651 PTMRDVFIELDRMQSKRKGTQSQAQNGEEHAHIQIAMPESMSLSYSSPN 699
>sp|P13368|7LESS_DROME Protein sevenless OS=Drosophila melanogaster
OX=7227 GN=sev PE=1 SV=2
Length=2554
Score = 256 bits (654), Expect = 4e-68, Method: Composition-based stats.
Identities = 79/367 (22%), Positives = 142/367 (39%), Gaps = 42/367 (11%)
Query 557 ETSNLIIMRGARASPRTLNLSQLSF-HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615
+T ++ RA TL+ + ++ +++ ++ L LG G VYEG+L+ E S +
Sbjct 2176 QTQQQLMAVRNRAFSTTLSDADIALLPQINWSQLKLLRFLGSGAFGEVYEGQLKTEDSEE 2235
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675
P+ RV +K L + A + A LMS H ++ + G
Sbjct 2236 PQ--------------------RVAIKSLRKGASEFA-ELLQEAQLMSNFKHENIVCLVG 2274
Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRERGH----------VPMAWKMVVAQQLASALSYL 725
+C ++ E++E G L +LR R + ++ + + +A+ SYL
Sbjct 2275 ICFDTESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMCIDVANGCSYL 2334
Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPWL 779
E+ + VH ++ RN L+ + +K+ D G+ + + + W+
Sbjct 2335 EDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDYYRKEGEGLLPVRWM 2394
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPS 837
+PE L G +T D W FG EI G+ P +R+ E + RL P
Sbjct 2395 SPESLVDGL--FTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEGGRLQQPPMC 2452
Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897
+L +L C +P +RPSFR L + + + +
Sbjct 2453 TEKLYSLLLLCWRTDPWERPSFRRCYNTLHAISTDLRRTQMASATADTVVSCSRPEFKVR 2512
Query 898 KKIRDLG 904
+ L
Sbjct 2513 FDGQPLE 2519
Score = 253 bits (645), Expect = 5e-67, Method: Composition-based stats.
Identities = 90/290 (31%), Positives = 134/290 (46%), Gaps = 38/290 (13%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG G FG+V + + VA+K+L+ G + QE ++ HE+I+
Sbjct 2214 FLGSGAFGEVYEGQLKTEDSEEPQRVAIKSLRK--GASEFAELLQEAQLMSNFKHENIVC 2271
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL------------PRHSIGLAQLLLFAQQICE 1009
G C D +S+ L+ME++ G L YL P + L++LL +
Sbjct 2272 LVGICFDT--ESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMCIDVAN 2329
Query 1010 GMAYLHAQHYIHRDLAARNVLL-------DNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
G +YL H++HRDLA RN L+ D R VKIGDFGLA+ + + +YYR +G
Sbjct 2330 GCSYLEDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKS-DYYRKEGEGL 2388
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
PV W +PE L + F SDVW+FGV +E+LT L
Sbjct 2389 LPVRWMSPESLVDGLFTTQSDVWAFGVLCWEILT--------------LGQQPYAARNNF 2434
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ ++ G RL +P C ++Y L+ CW T+ RP+F L +
Sbjct 2435 EVLAHVKEGGRLQQPPMCTEKLYSLLLLCWRTDPWERPSFRRCYNTLHAI 2484
>sp|C0LGG8|Y5343_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g53430 OS=Arabidopsis thaliana OX=3702
GN=At1g53430 PE=1 SV=1
Length=1038
Score = 253 bits (645), Expect = 4e-68, Method: Composition-based stats.
Identities = 77/285 (27%), Positives = 122/285 (43%), Gaps = 19/285 (7%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+GEG FG V G +AVK L + Q + EI ++ L
Sbjct 667 NNFDPENKIGEGGFGPVYKGVL-----ADGMTIAVKQLSSK-SKQGNREFVTEIGMISAL 720
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICE 1009
H +++K GCC + E L LV EY+ SL L R + + I +
Sbjct 721 QHPNLVKLYGCCIEGKE--LLLVYEYLENNSLARALFGTEKQRLHLDWSTRNKICIGIAK 778
Query 1010 GMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G+AYLH + +HRD+ A NVLLD KI DFGLAK + + + R G +
Sbjct 779 GLAYLHEESRLKIVHRDIKATNVLLDLSLNAKISDFGLAKLNDDENTHISTRIAG--TIG 836
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHC-DSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+ APE +DV+SFGV E+++ +++ P +F+ L+ A L
Sbjct 837 YMAPEYAMRGYLTDKADVYSFGVVCLEIVSGKSNTNYRPKEEFVYLLDWAYVLQEQGSLL 896
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
EL++ K + ++ C + RP +++ +L+
Sbjct 897 ELVDPDLGTSFSKKEAMRMLNIALLCTNPSPTLRPPMSSVVSMLE 941
Score = 234 bits (596), Expect = 6e-62, Method: Composition-based stats.
Identities = 70/366 (19%), Positives = 123/366 (34%), Gaps = 70/366 (19%)
Query 529 LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKE 588
+ AA L LR E +RG + L Q+ +
Sbjct 615 VIAACAVFGLLV---LVILRLTGYLGGKEVDENEELRGLDLQTGSFTLKQI---KRATNN 668
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+ +G+G VY+G L + + +K L
Sbjct 669 FDPENKIGEGGFGPVYKGVLADG-------------------------MTIAVKQLSSKS 703
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR---RERGH 705
F ++S + H +L ++G C+ G E ++V EY+E+ L L ++R H
Sbjct 704 KQGNREFVTEIGMISALQHPNLVKLYGCCIEGKELLLVYEYLENNSLARALFGTEKQRLH 763
Query 706 VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ + + + +A L+YL + +VH ++ N+LL S K+SD G+
Sbjct 764 LDWSTRNKICIGIAKGLAYLHEESRLKIVHRDIKATNVLLD-------LSLNAKISDFGL 816
Query 763 GLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ I ++APE G L+ D + FG LEI G++
Sbjct 817 AKLNDDENTHISTRIAGTIGYMAPEYAMRGY--LTDKADVYSFGVVCLEIVS-GKSNTNY 873
Query 818 RSPSEKEHFYQRQHRLPEPSC------------------PQLATLTSQCLTYEPTQRPSF 859
R E + + L E ++ + C PT RP
Sbjct 874 RPKEEFVYLLDWAYVLQEQGSLLELVDPDLGTSFSKKEAMRMLNIALLCTNPSPTLRPPM 933
Query 860 RTILRD 865
+++
Sbjct 934 SSVVSM 939
>sp|P30530|UFO_HUMAN Tyrosine-protein kinase receptor UFO OS=Homo
sapiens OX=9606 GN=AXL PE=1 SV=4
Length=894
Score = 250 bits (639), Expect = 5e-68, Method: Composition-based stats.
Identities = 85/282 (30%), Positives = 127/282 (45%), Gaps = 29/282 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHII 960
LGEG FG V + D + VAVK +K A C + E ++ H +++
Sbjct 541 TLGEGEFGAVMEGQLN--QDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVM 598
Query 961 KYKGCCEDQGEK----SLQLVMEYVPLGSLRDYLPRHSIGLA-------QLLLFAQQICE 1009
+ G C E+ + +++ ++ G L +L +G L+ F I
Sbjct 599 RLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGDQPVYLPTQMLVKFMADIAS 658
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
GM YL + +IHRDLAARN +L+ + V + DFGL+K + G +YYR PV W A
Sbjct 659 GMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNG-DYYRQGRIAKMPVKWIA 717
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E L + + SDVWSFGVT++E+ T + + + L
Sbjct 718 IESLADRVYTSKSDVWSFGVTMWEIATRGQ--------------TPYPGVENSEIYDYLR 763
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+G RL +P C +Y LM CWE RP+F L L+
Sbjct 764 QGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTELREDLEN 805
Score = 224 bits (572), Expect = 2e-59, Method: Composition-based stats.
Identities = 67/307 (22%), Positives = 117/307 (38%), Gaps = 52/307 (17%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
+L VD+ ++ LG+G V EG+L + S L
Sbjct 525 KLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSI----------------------L 562
Query 638 RVVLKVLDP--SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN------IMVTEY 689
+V +K + F A M + H ++ + GVC +G E +++ +
Sbjct 563 KVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPF 622
Query 690 VEHGPLDVWLRRERG-----HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
++HG L +L R ++P + +AS + YL K +H ++ RN +L
Sbjct 623 MKHGDLHSFLLYSRLGDQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNE 682
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKW 798
+ + ++D G+ + + + W+A E L ++ D W
Sbjct 683 -------NMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRV--YTSKSDVW 733
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
FG T+ EI G+ P SE + ++ +RL P L L S+C P R
Sbjct 734 SFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQDR 793
Query 857 PSFRTIL 863
PSF +
Sbjct 794 PSFTELR 800
>sp|P08923|LTK_MOUSE Leukocyte tyrosine kinase receptor OS=Mus
musculus OX=10090 GN=Ltk PE=1 SV=3
Length=888
Score = 250 bits (638), Expect = 5e-68, Method: Composition-based stats.
Identities = 91/391 (23%), Positives = 140/391 (36%), Gaps = 58/391 (15%)
Query 516 LEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCC-------LPQPGETSNLIIMRGAR 568
L + + AAL LL + + C LP P + + R
Sbjct 415 LPTTASPLILMGAVVAALALSLLMMCAVLILVNQKCQGLWGTRLPGPELELSKLRSSAIR 474
Query 569 ASPRTL----NLSQLS-------FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
+P LS V +T L LG G VYEG +
Sbjct 475 TAPNPYYCQVGLSPAQPWPLPPGLTEVSPANVTLLRALGHGAFGEVYEGLV--------- 525
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGV 676
G D PL V +K L H L F A ++S+ SH ++ G+
Sbjct 526 TGLPGDSSPLP----------VAIKTLPELCSHQDELDFLMEALIISKFSHQNIVRCVGL 575
Query 677 CVRGPENIMVTEYVEHGPLDVWLRRERGH------VPMAWKMVVAQQLASALSYLENKNL 730
R +++ E + G + +LR R H + M + +AQ +A YLE +
Sbjct 576 SFRSAPRLILLELMSGGDMKSFLRHSRPHPGQLAPLTMQDLLQLAQDIAQGCHYLEENHF 635
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECL 784
+H ++ RN LL+ G S K+ D G+ + + W+ PE L
Sbjct 636 IHRDIAARNCLLS----CSGASRVAKIGDFGMARDIYQASYYRKGGRTLLPVKWMPPEAL 691
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLA 842
G ++ D W FG L EI G P + E F +R+ P +CP +
Sbjct 692 LEGL--FTSKTDSWSFGVLLWEIFSLGYMPYPGHTNQEVLDFIATGNRMDPPRNCPGPVY 749
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
+ +QC ++P RP F +IL +
Sbjct 750 RIMTQCWQHQPELRPDFGSILERIQYCTQDP 780
Score = 244 bits (624), Expect = 4e-66, Method: Composition-based stats.
Identities = 87/295 (29%), Positives = 129/295 (44%), Gaps = 34/295 (12%)
Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG G FG+V D + VA+K L C Q + E I+ H++I++
Sbjct 512 LGHGAFGEVYEGLVTGLPGDSSPLPVAIKTLPELCSHQDELDFLMEALIISKFSHQNIVR 571
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--------SIGLAQLLLFAQQICEGMAY 1013
G + + L E + G ++ +L + + LL AQ I +G Y
Sbjct 572 CVGLSFRSAPRLILL--ELMSGGDMKSFLRHSRPHPGQLAPLTMQDLLQLAQDIAQGCHY 629
Query 1014 LHAQHYIHRDLAARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
L H+IHRD+AARN LL + KIGDFG+A+ + + YYR PV W P
Sbjct 630 LEENHFIHRDIAARNCLLSCSGASRVAKIGDFGMARDIYQA-SYYRKGGRTLLPVKWMPP 688
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E L E F +D WSFGV L+E+ + L + T + + +
Sbjct 689 EALLEGLFTSKTDSWSFGVLLWEIFS--------------LGYMPYPGHTNQEVLDFIAT 734
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
G R+ P CP VY +M CW+ + RP F ++ L+ + Y Q P V +
Sbjct 735 GNRMDPPRNCPGPVYRIMTQCWQHQPELRPDFGSI---LERIQ--YCTQDPDVLN 784
>sp|O64842|PBL12_ARATH Probable serine/threonine-protein kinase
PBL12 OS=Arabidopsis thaliana OX=3702 GN=PBL12 PE=2 SV=1
Length=424
Score = 238 bits (608), Expect = 6e-68, Method: Composition-based stats.
Identities = 90/339 (27%), Positives = 143/339 (42%), Gaps = 14/339 (4%)
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
C ++ ++ + + + S+ V + + LG
Sbjct 37 IRTCPAFKRLSLSDISDPSSPMSVMDDLSHSFTSQKLRLFTLSELRVITHNFSRSNM-LG 95
Query 905 EGHFGKVSLYCYDPTND--GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
EG FG V D + VAVKAL HR W EI L L ++H++K
Sbjct 96 EGGFGPVYKGFIDDKVKPGIEAQPVAVKALDLHGHQGHRE-WLAEILFLGQLSNKHLVKL 154
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA--Q 1017
G C ++ ++ LV EY+P GSL + L R + + + A +G+A+LH +
Sbjct 155 IGFCCEEEQR--VLVYEYMPRGSLENQLFRRNSLAMAWGIRMKIALGAAKGLAFLHEAEK 212
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
I+RD N+LLD+D K+ DFGLAK PEG E+ V + APE +
Sbjct 213 PVIYRDFKTSNILLDSDYNAKLSDFGLAKDGPEG-EHTHVTTRVMGTQGYAAPEYIMTGH 271
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+DV+SFGV L EL+T S + T + L+ A+ + R E + +
Sbjct 272 LTTMNDVYSFGVVLLELITGKRSMDNTRTRREQSLVEWARPMLRDQRKLERIIDPRLANQ 331
Query 1137 PDKCPCEV-YHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+V L C +RPT ++ +L+++ E
Sbjct 332 HKTEAAQVAASLAYKCLSQHPKYRPTMCEVVKVLESIQE 370
Score = 226 bits (577), Expect = 8e-64, Method: Composition-based stats.
Identities = 83/370 (22%), Positives = 143/370 (39%), Gaps = 56/370 (15%)
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P +++ + + L L LS RV ++ + LG+G VY+G +
Sbjct 54 PSSPMSVMDDLSHSFTSQKLRLFTLSELRVITHNFSRSNMLGEGGFGPVYKGFI------ 107
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+D + PG + V +K LD H + + Q+S+ HL +
Sbjct 108 ---------DDKVKPGI---EAQPVAVKALDLHGHQGHREWLAEILFLGQLSNKHLVKLI 155
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE--NKNL 730
G C + ++V EY+ G L+ L R R + MAW +M +A A L++L K +
Sbjct 156 GFCCEEEQRVLVYEYMPRGSLENQLFR-RNSLAMAWGIRMKIALGAAKGLAFLHEAEKPV 214
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECL 784
++ + NILL + KLSD G+ E + + APE +
Sbjct 215 IYRDFKTSNILLD-------SDYNAKLSDFGLAKDGPEGEHTHVTTRVMGTQGYAAPEYI 267
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ------RQHRLPEPSC 838
G L+T D + FG LLE+ + +R+ E+ Q +L
Sbjct 268 MTG--HLTTMNDVYSFGVVLLELITGKRSMDNTRTRREQSLVEWARPMLRDQRKLERIID 325
Query 839 PQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
P+L A+L +CL+ P RP+ +++ L +Q ++ N
Sbjct 326 PRLANQHKTEAAQVAASLAYKCLSQHPKYRPTMCEVVKVLESIQEVDIRKHDGNNNKEGK 385
Query 887 SDPTVFHKRY 896
+ R+
Sbjct 386 KFVDINKFRH 395
>sp|A0A0P0XII1|CERK1_ORYSJ Chitin elicitor receptor kinase 1 OS=Oryza
sativa subsp. japonica OX=39947 GN=CERK1 PE=1 SV=1
Length=624
Score = 244 bits (623), Expect = 7e-68, Method: Composition-based stats.
Identities = 64/285 (22%), Positives = 114/285 (40%), Gaps = 26/285 (9%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G+G FG V GE A+K + + + E+ +L ++H +++
Sbjct 328 NKIGQGGFGAVYYAELR------GEKAAIKKMDMQATHE----FLAELKVLTHVHHLNLV 377
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ G C E SL LV E++ G+L +L + A + A G+ Y+H
Sbjct 378 RLIGYCI---ESSLFLVYEFIENGNLSQHLRGMGYEPLSWAARIQIALDSARGLEYIHEH 434
Query 1018 HY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRD+ + N+L+D + K+ DFGL K G + PE +
Sbjct 435 TVPVYIHRDIKSANILIDKNYRAKVADFGLTKLTEVGGTSMPTGTRVVGTFGYMPPEYAR 494
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE-------L 1127
DV++FGV LYEL++ ++ + G+ L + L
Sbjct 495 YGDVSPKVDVYAFGVVLYELISAKEAIVRSTESSSDSKGLVYLFEEALNSPDPKEGLRTL 554
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
++ P ++ L K C + + RP+ +++ L T+
Sbjct 555 IDPKLGEDYPIDSILKLTQLAKVCTQEDPKLRPSMRSVVVALMTL 599
Score = 197 bits (502), Expect = 4e-52, Method: Composition-based stats.
Identities = 66/329 (20%), Positives = 119/329 (36%), Gaps = 77/329 (23%)
Query 578 QLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
+ S+ + + + + +GQG VY LR E
Sbjct 311 EFSYEELSNATQGFSIGNKIGQGGFGAVYYAELRGE------------------------ 346
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+ +K +D F +++ V H +L + G C+ +V E++E+G L
Sbjct 347 --KAAIKKMD---MQATHEFLAELKVLTHVHHLNLVRLIGYCIESS-LFLVYEFIENGNL 400
Query 696 DVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNL---VHGNVCGRNILLARLGLAEG 750
LR G+ P++W ++ +A A L Y+ + +H ++ NIL+ +
Sbjct 401 SQHLRG-MGYEPLSWAARIQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDK------ 453
Query 751 TSPFIKLSDPGV-------GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+ K++D G+ G + V ++ PE G +S +D + FG
Sbjct 454 -NYRAKVADFGLTKLTEVGGTSMPTGTRVVGTFGYMPPEYARYG--DVSPKVDVYAFGVV 510
Query 804 LLEICFDGEAPLQSRSPS-----------EKEHFYQRQHRLPEPSCPQLAT--------- 843
L E+ EA ++S S E + + L P+L
Sbjct 511 LYELISAKEAIVRSTESSSDSKGLVYLFEEALNSPDPKEGLRTLIDPKLGEDYPIDSILK 570
Query 844 ---LTSQCLTYEPTQRPSFRTILRDLTRL 869
L C +P RPS R+++ L L
Sbjct 571 LTQLAKVCTQEDPKLRPSMRSVVVALMTL 599
>sp|Q54XQ2|RCKA_DICDI RGS domain-containing serine/threonine-protein
kinase A OS=Dictyostelium discoideum OX=44689 GN=rckA
PE=1 SV=1
Length=1125
Score = 253 bits (645), Expect = 7e-68, Method: Composition-based stats.
Identities = 73/321 (23%), Positives = 130/321 (40%), Gaps = 31/321 (10%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
+ L ++ ++ S T + + + G G+V
Sbjct 800 SITLDNDEDPTIFHLDESDMESLIEEVVKDNISVHTEISYSDVSIHKWIASGSSGRVYNG 859
Query 915 CYDPTNDGTGEMVAVKALKADCGPQ-HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
Y G+ VA+K L + + +K+E+ ++ H+++ + G +K
Sbjct 860 QYK------GKDVAIKVLGPEVCVHFDLNEFKREVALMSIFKHDNLARCLGA-GQYDDKY 912
Query 974 LQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031
L EY GSL YL R++I Q L FA I GM YLH+ IHRDL + N+LL
Sbjct 913 FHL-TEYCHNGSLFSYLRDQRNNISFGQRLHFALGIARGMRYLHSMSIIHRDLKSMNILL 971
Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091
+KI DFG ++ + + W APE + DV+S+ + L
Sbjct 972 TKRLKIKIVDFGTSRVANKYN-----MTTHVGTQAWMAPEIFTSRTYTNKVDVYSYAIIL 1026
Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
+E+ T A + + + ++ +GER P + +++K C
Sbjct 1027 FEIFTRKS---------------AYDENANINIPNMVMKGERPELPKDMQTSISNIIKKC 1071
Query 1152 WETEASFRPTFENLIPILKTV 1172
W+ + S RP+F ++ L+++
Sbjct 1072 WQQKPSNRPSFIKIVAYLESI 1092
Score = 216 bits (551), Expect = 4e-56, Method: Composition-based stats.
Identities = 61/297 (21%), Positives = 115/297 (39%), Gaps = 44/297 (15%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
+ +++ + G+ VY G+ + + V +K
Sbjct 836 EISYSDVSIHKWIASGSSGRVYNGQYKGKD--------------------------VAIK 869
Query 643 VLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
VL P H D+ F +LMS H +LA G + +TEY +G L +L
Sbjct 870 VLGPEVCVHFDLN-EFKREVALMSIFKHDNLARCLGAGQYDDKYFHLTEYCHNGSLFSYL 928
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R +R ++ ++ A +A + YL + +++H ++ NILL + IK+ D
Sbjct 929 RDQRNNISFGQRLHFALGIARGMRYLHSMSIIHRDLKSMNILLTK-------RLKIKIVD 981
Query 760 PGVGL--GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
G + V W+APE + + + +D + + L EI F ++
Sbjct 982 FGTSRVANKYNMTTHVGTQAWMAPEIFT--SRTYTNKVDVYSYAIILFEI-FTRKSAYDE 1038
Query 818 RSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
+ + + R LP+ ++ + +C +P+ RPSF I+ L +
Sbjct 1039 NANINIPNMVMKGERPELPKDMQTSISNIIKKCWQQKPSNRPSFIKIVAYLESIIYP 1095
>sp|O64783|Y1137_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61370 OS=Arabidopsis thaliana OX=3702
GN=At1g61370 PE=3 SV=2
Length=814
Score = 248 bits (633), Expect = 8e-68, Method: Composition-based stats.
Identities = 71/311 (23%), Positives = 129/311 (41%), Gaps = 17/311 (5%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
+ + + LG+G FG V N G+ +A+K L + G
Sbjct 483 PQDVNFFDMQTILTITNNFSMENKLGQGGFGPVYKG-----NLQDGKEIAIKRLSSTSG- 536
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHS 994
Q + EI ++ L H ++++ GCC + EK L+ E++ SL ++ +
Sbjct 537 QGLEEFMNEIILISKLQHRNLVRLLGCCIEGEEK--LLIYEFMANKSLNTFIFDSTKKLE 594
Query 995 IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
+ + Q I G+ YLH +HRD+ N+LLD + KI DFGLA+ +G
Sbjct 595 LDWPKRFEIIQGIACGLLYLHRDSCLRVVHRDMKVSNILLDEEMNPKISDFGLARMF-QG 653
Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLE 1110
++ + + +PE F SD+++FGV L E++T SS + +
Sbjct 654 TQHQANTRRVVGTLGYMSPEYAWTGMFSEKSDIYAFGVLLLEIITGKRISSFTIGEEGKT 713
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
L+ A ++LL++ + + C + +A RP ++ +L
Sbjct 714 LLEFAWDSWCESGGSDLLDQDISSSGSESEVARCVQIGLLCIQQQAGDRPNIAQVMSMLT 773
Query 1171 TVHEKYQGQAP 1181
T + + + P
Sbjct 774 TTMDLPKPKQP 784
Score = 230 bits (586), Expect = 1e-61, Method: Composition-based stats.
Identities = 51/258 (20%), Positives = 93/258 (36%), Gaps = 45/258 (17%)
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
+ P+ +N + + + LGQG VY+G L+
Sbjct 478 REQLKPQDVNFFDMQTILTITNNFSMENKLGQGGFGPVYKGNLQDGK------------- 524
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
+ +K L + F L+S++ H +L + G C+ G E ++
Sbjct 525 ------------EIAIKRLSSTSGQGLEEFMNEIILISKLQHRNLVRLLGCCIEGEEKLL 572
Query 686 VTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNI 740
+ E++ + L+ ++ + + W + + Q +A L YL +VH ++ NI
Sbjct 573 IYEFMANKSLNTFIFDSTKKLELDWPKRFEIIQGIACGLLYLHRDSCLRVVHRDMKVSNI 632
Query 741 LLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTA 794
LL K+SD G+ + V + +++PE G S
Sbjct 633 LLDEE-------MNPKISDFGLARMFQGTQHQANTRRVVGTLGYMSPEYAWTGM--FSEK 683
Query 795 MDKWGFGATLLEICFDGE 812
D + FG LLEI
Sbjct 684 SDIYAFGVLLLEIITGKR 701
>sp|Q9LDQ3|CRK34_ARATH Cysteine-rich receptor-like protein kinase
34 OS=Arabidopsis thaliana OX=3702 GN=CRK34 PE=3 SV=3
Length=669
Score = 244 bits (624), Expect = 1e-67, Method: Composition-based stats.
Identities = 74/278 (27%), Positives = 113/278 (41%), Gaps = 18/278 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG+V +G VAVK L G Q +K E ++ L H+++++
Sbjct 351 IGRGGFGEVYRG-----KLSSGPEVAVKRLSKTSG-QGAEEFKNEAVLVSKLQHKNLVRL 404
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
G C + EK LV E+VP SL +L + + + I G+ YLH
Sbjct 405 LGFCLEGEEK--ILVYEFVPNKSLDYFLFDPAKQGELDWTRRYNIIGGIARGILYLHQDS 462
Query 1019 ---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
IHRDL A N+LLD D KI DFG+A+ R + +PE
Sbjct 463 RLTIIHRDLKASNILLDADMNPKIADFGMARIFGVDQSQANTRRIA-GTFGYMSPEYAMR 521
Query 1076 YKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
F SDV+SFGV + E+++ S + L+ A EL++
Sbjct 522 GHFSMKSDVYSFGVLVLEIISGKKNSSFYNIDDSGSNLVTHAWRLWRNGSPLELVDPTIG 581
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
H+ C + + + RP +I +L +
Sbjct 582 ESYQSSEATRCIHIALLCVQEDPADRPLLPAIIMMLTS 619
Score = 239 bits (610), Expect = 9e-66, Method: Composition-based stats.
Identities = 61/324 (19%), Positives = 110/324 (34%), Gaps = 65/324 (20%)
Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
T + Q SF ++ + + + +G+G VY G+L
Sbjct 327 TTHSLQFSFKTIEAATDKFSDSNMIGRGGFGEVYRGKLSSGP------------------ 368
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
V +K L + A F A L+S++ H +L + G C+ G E I+V E+V
Sbjct 369 -------EVAVKRLSKTSGQGAEEFKNEAVLVSKLQHKNLVRLLGFCLEGEEKILVYEFV 421
Query 691 EHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745
+ LD +L ++G + + + +A + YL + ++H ++ NILL
Sbjct 422 PNKSLDYFLFDPAKQGELDWTRRYNIIGGIARGILYLHQDSRLTIIHRDLKASNILLD-- 479
Query 746 GLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
K++D G+ + +++PE G S D +
Sbjct 480 -----ADMNPKIADFGMARIFGVDQSQANTRRIAGTFGYMSPEYAMRG--HFSMKSDVYS 532
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------------QL 841
FG +LEI + + RL P +
Sbjct 533 FGVLVLEIISGKKNSSFYNIDDSGSNLVTHAWRLWRNGSPLELVDPTIGESYQSSEATRC 592
Query 842 ATLTSQCLTYEPTQRPSFRTILRD 865
+ C+ +P RP I+
Sbjct 593 IHIALLCVQEDPADRPLLPAIIMM 616
>sp|Q9ASQ6|Y1972_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g29720 OS=Arabidopsis thaliana OX=3702
GN=RFK1 PE=2 SV=3
Length=1019
Score = 251 bits (641), Expect = 1e-67, Method: Composition-based stats.
Identities = 74/297 (25%), Positives = 119/297 (40%), Gaps = 17/297 (6%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH 940
+ + LGEG FG V G ++AVK L + +
Sbjct 657 QTVCFSWRQLQTATNNFDQANKLGEGGFGSVFKGEL-----SDGTIIAVKQLSSKSSQGN 711
Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGL 997
R + EI ++ L H +++K GCC ++ + L LV EY+ SL L +
Sbjct 712 RE-FVNEIGMISGLNHPNLVKLYGCCVERDQ--LLLVYEYMENNSLALALFGQNSLKLDW 768
Query 998 AQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
A I G+ +LH +HRD+ NVLLD D KI DFGLA+ H +
Sbjct 769 AARQKICVGIARGLEFLHDGSAMRMVHRDIKTTNVLLDTDLNAKISDFGLARLHEAEHTH 828
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC-DSSQSPPTKFLELIG 1113
+ G + + APE + +DV+SFGV E+++ ++ Q + LI
Sbjct 829 ISTKVAG--TIGYMAPEYALWGQLTEKADVYSFGVVAMEIVSGKSNTKQQGNADSVSLIN 886
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
A + E+++R + + C + S RPT + +L+
Sbjct 887 WALTLQQTGDILEIVDRMLEGEFNRSEAVRMIKVALVCTNSSPSLRPTMSEAVKMLE 943
Score = 220 bits (560), Expect = 2e-57, Method: Composition-based stats.
Identities = 52/281 (19%), Positives = 101/281 (36%), Gaps = 47/281 (17%)
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
+R + QL Q + LG+G +V++G L
Sbjct 651 LRAQGLQTVCFSWRQLQT---ATNNFDQANKLGEGGFGSVFKGELSDG------------ 695
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
+ +K L F ++S ++H +L ++G CV +
Sbjct 696 -------------TIIAVKQLSSKSSQGNREFVNEIGMISGLNHPNLVKLYGCCVERDQL 742
Query 684 IMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRN 739
++V EY+E+ L + L + + A + + +A L +L + +VH ++ N
Sbjct 743 LLVYEYMENNSLALALFGQNSLKLDWAARQKICVGIARGLEFLHDGSAMRMVHRDIKTTN 802
Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTA 794
+LL T K+SD G+ + + I ++APE G L+
Sbjct 803 VLLD-------TDLNAKISDFGLARLHEAEHTHISTKVAGTIGYMAPEYALWG--QLTEK 853
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
D + FG +EI G++ + + ++ L +
Sbjct 854 ADVYSFGVVAMEIVS-GKSNTKQQGNADSVSLINWALTLQQ 893
>sp|O61460|VAB1_CAEEL Ephrin receptor 1 OS=Caenorhabditis elegans
OX=6239 GN=vab-1 PE=1 SV=1
Length=1122
Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats.
Identities = 85/349 (24%), Positives = 133/349 (38%), Gaps = 52/349 (15%)
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916
P + + + + + + + + + +G G FG V L
Sbjct 652 PYYGGVHPNSGKYKTYVDPTTYEDPYQALIEFTFDISPNDVFITQVIGGGEFGDVCLGGL 711
Query 917 DPTNDGTG-----------------------EMVAVKALKADCGPQHRSGWKQEIDILRT 953
+ E VA+K LK+ + ++ + E I+
Sbjct 712 SKNSPAAAKWSVSNTTMGRGGGGGGYESEPYETVAIKTLKSGSSAKAKAEFLTEATIMGQ 771
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQIC 1008
H ++I+ G + + +V EY+ GSL +L + ++ I
Sbjct 772 FSHPNVIRLIGVVTSA--EPVMIVAEYMANGSLDQFLRNTDQRGEKVHWEKITEMLYGIA 829
Query 1009 EGMAYLHAQHYIHR-----DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR---VRED 1060
GM YL Y+HR DLAARNVLLD + KI DFGL++ V
Sbjct 830 SGMKYLTDMGYVHRVSFLRDLAARNVLLDMELRCKIADFGLSRGVRSEGSSVEPEYTTNG 889
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
G PV W APE + KF +SDVWSFGV ++E+ + + T
Sbjct 890 GKIPVRWTAPEAITHRKFTPSSDVWSFGVVIWEVCSFGER--------------PYWDWT 935
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
++ + G RLP P CP +Y + + CW+ E RPTF L+
Sbjct 936 NQKVISEVMIGYRLPPPMDCPMGLYRIAQWCWKMERHERPTFTQLLATF 984
Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats.
Identities = 69/321 (21%), Positives = 112/321 (35%), Gaps = 33/321 (10%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL---RVV 640
+ ++ +G G +V G L + + G + V
Sbjct 687 ISPNDVFITQVIGGGEFGDVCLGGLSKNSPAAAKWSVSNTTMGRGGGGGGYESEPYETVA 746
Query 641 LKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+K L F A++M Q SH ++ + GV ++V EY+ +G LD +L
Sbjct 747 IKTLKSGSSAKAKAEFLTEATIMGQFSHPNVIRLIGVVTSAEPVMIVAEYMANGSLDQFL 806
Query 700 RRER---GHVPMAWKMVVAQQLASALSYLENKNLVH-----GNVCGRNILLARLGLAEGT 751
R V + +AS + YL + VH ++ RN+LL
Sbjct 807 RNTDQRGEKVHWEKITEMLYGIASGMKYLTDMGYVHRVSFLRDLAARNVLLD-------M 859
Query 752 SPFIKLSDPGVGLGALSREERVE----------RIPWLAPECLPGGANSLSTAMDKWGFG 801
K++D G+ G S VE + W APE + + + D W FG
Sbjct 860 ELRCKIADFGLSRGVRSEGSSVEPEYTTNGGKIPVRWTAPEAITH--RKFTPSSDVWSFG 917
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSF 859
+ E+C GE P + + +RLP P CP L + C E +RP+F
Sbjct 918 VVIWEVCSFGERPYWDWTNQKVISEVMIGYRLPPPMDCPMGLYRIAQWCWKMERHERPTF 977
Query 860 RTILRDLTRLQPHNLADVLTV 880
+L +
Sbjct 978 TQLLATFHKYILQPTLIEHDP 998
>sp|Q8QFP9|TYRO3_XENLA Tyrosine-protein kinase receptor TYRO3
OS=Xenopus laevis OX=8355 GN=tyro3 PE=1 SV=1
Length=880
Score = 249 bits (635), Expect = 1e-67, Method: Composition-based stats.
Identities = 90/293 (31%), Positives = 134/293 (46%), Gaps = 28/293 (10%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG-PQHRSGWKQEIDIL 951
++ R LG+G FG V D T + VAVK LKA+ + +E +
Sbjct 499 QQQQFTLGRTLGKGEFGSVREAQLK-MEDDTMQKVAVKMLKAEIFCSSDIEEFLREAAFM 557
Query 952 RTLYHEHIIKYKGC-CEDQGEKSL---QLVMEYVPLGSLRDYLPRHSIGLA-------QL 1000
+ H ++ K G + + L +++ ++ G L +L IG L
Sbjct 558 KEFDHPNVCKLIGVSLRSRTKGRLPVPMVILPFMKHGDLHTFLLMSRIGEEPITLPVQTL 617
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+ F IC GM YL ++++IHRDLA RN +L+ D V + DFGL+K + G +YYR
Sbjct 618 VRFMIDICSGMEYLSSKNFIHRDLATRNCMLNEDMTVCVADFGLSKKIYSG-DYYRQGCA 676
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
PV W A E L + + SDVW+FGVTL+E+ T L +
Sbjct 677 SKLPVKWLALESLADNVYTVHSDVWAFGVTLWEIAT--------------LGQTPYAGVE 722
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ L G RL +P C E+Y +M CW TE RP+F +L L+ +
Sbjct 723 NSEIYSYLIAGNRLKQPLDCLDELYEMMCQCWITEPKRRPSFVDLKQRLEAIW 775
Score = 221 bits (564), Expect = 2e-58, Method: Composition-based stats.
Identities = 70/314 (22%), Positives = 122/314 (39%), Gaps = 51/314 (16%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S+L + Q++ T LG+G +V E +L++E
Sbjct 491 SKLKDVLIQQQQFTLGRTLGKGEFGSVREAQLKMED---------------------DTM 529
Query 637 LRVVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTE 688
+V +K+L F A+ M + H ++ + GV +R P +++
Sbjct 530 QKVAVKMLKAEIFCSSDIEEFLREAAFMKEFDHPNVCKLIGVSLRSRTKGRLPVPMVILP 589
Query 689 YVEHGPLDVWLRRERG-----HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+++HG L +L R +P+ + + S + YL +KN +H ++ RN +L
Sbjct 590 FMKHGDLHTFLLMSRIGEEPITLPVQTLVRFMIDICSGMEYLSSKNFIHRDLATRNCMLN 649
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDK 797
+ ++D G+ S + + + WLA E L + D
Sbjct 650 E-------DMTVCVADFGLSKKIYSGDYYRQGCASKLPVKWLALESLADNV--YTVHSDV 700
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855
W FG TL EI G+ P SE + +RL P +L + QC EP +
Sbjct 701 WAFGVTLWEIATLGQTPYAGVENSEIYSYLIAGNRLKQPLDCLDELYEMMCQCWITEPKR 760
Query 856 RPSFRTILRDLTRL 869
RPSF + + L +
Sbjct 761 RPSFVDLKQRLEAI 774
>sp|Q54PX0|Y4251_DICDI Probable serine/threonine-protein kinase
DDB_G0284251 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0284251
PE=3 SV=1
Length=496
Score = 239 bits (611), Expect = 1e-67, Method: Composition-based stats.
Identities = 75/268 (28%), Positives = 126/268 (47%), Gaps = 26/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHII 960
+G G FG+V + N TGE VA+K + ++ K E++IL L H +I+
Sbjct 41 KIGRGAFGQV----FKGLNGKTGEFVAIKQIDSNKIDESSLQSVKGEVEILHKLRHNNIV 96
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHY 1019
K G E Q + L ++EYV GSLRD + + + +++ Q+ +G+AYLH+
Sbjct 97 KVLGVVEVQAQ--LNFILEYVENGSLRDVIEKFGPLSEELCIIYLYQMLQGLAYLHSNKV 154
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+L+ + ++K+ DFG+A + ++R +W APE ++
Sbjct 155 IHRDIKASNILITKEGVIKLADFGVASQIDSES---QLRFSVVGTPYWMAPESIEISGCS 211
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
ASD+WS G T+ ELLT + Q + R+ + P P
Sbjct 212 SASDIWSLGSTMIELLTGNPPYYT-----------LQPMAAMFRIVS----DQHPPFPTD 256
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
E + ++ + + RPT + L+
Sbjct 257 ISKEFLDYFQQSFKKDPTQRPTAQELLQ 284
Score = 205 bits (521), Expect = 1e-55, Method: Composition-based stats.
Identities = 61/290 (21%), Positives = 111/290 (38%), Gaps = 43/290 (15%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
E T +G+G V++G G V +K +D +
Sbjct 35 EYTLGEKIGRGAFGQVFKGLNGKTGEF------------------------VAIKQIDSN 70
Query 648 HHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
D + + ++ ++ H ++ V GV + + EYVE+G L + + G
Sbjct 71 KIDESSLQSVKGEVEILHKLRHNNIVKVLGVVEVQAQLNFILEYVENGSLRDVI-EKFGP 129
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+ ++ Q+ L+YL + ++H ++ NIL+ + G+ IKL+D GV
Sbjct 130 LSEELCIIYLYQMLQGLAYLHSNKVIHRDIKASNILITKEGV-------IKLADFGVASQ 182
Query 766 ALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
S V W+APE + + S+A D W G+T++E+ G P + P
Sbjct 183 IDSESQLRFSVVGTPYWMAPESIE--ISGCSSASDIWSLGSTMIELL-TGNPPYYTLQPM 239
Query 822 EKEH--FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ P + Q +PTQRP+ + +L+
Sbjct 240 AAMFRIVSDQHPPFPTDISKEFLDYFQQSFKKDPTQRPTAQELLQHPIFF 289
>sp|Q9S972|SD16_ARATH Receptor-like serine/threonine-protein kinase
SD1-6 OS=Arabidopsis thaliana OX=3702 GN=SD16 PE=1 SV=2
Length=847
Score = 248 bits (633), Expect = 2e-67, Method: Composition-based stats.
Identities = 73/297 (25%), Positives = 115/297 (39%), Gaps = 21/297 (7%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
LG+G FG V G+ +AVK L Q +
Sbjct 511 MEWKALAMATNNFSTDNKLGQGGFGIVYKGML-----LDGKEIAVKRLSK-MSSQGTDEF 564
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQL 1000
E+ ++ L H ++++ GCC D+GEK L+ EY+ SL +L ++ +
Sbjct 565 MNEVRLIAKLQHINLVRLLGCCVDKGEK--MLIYEYLENLSLDSHLFDQTRSSNLNWQKR 622
Query 1001 LLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
I G+ YLH IHRDL A NVLLD + KI DFG+A+
Sbjct 623 FDIINGIARGLLYLHQDSRCRIIHRDLKASNVLLDKNMTPKISDFGMARIFGREETEANT 682
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQ 1116
R + +PE + F SDV+SFGV L E+++ + L L+G
Sbjct 683 RR-VVGTYGYMSPEYAMDGIFSMKSDVFSFGVLLLEIISGKRNKGFYNSNRDLNLLGFVW 741
Query 1117 GQMTVLRLTELLERGERLPRPDKCPC----EVYHLMKNCWETEASFRPTFENLIPIL 1169
+ E+++ + P + C + A RP +++ +L
Sbjct 742 RHWKEGKELEIVDPINIDALSSEFPTHEILRCIQIGLLCVQERAEDRPVMSSVMVML 798
Score = 225 bits (574), Expect = 5e-60, Method: Composition-based stats.
Identities = 52/274 (19%), Positives = 91/274 (33%), Gaps = 47/274 (17%)
Query 566 GARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
L L + + + + + LGQG VY+G L
Sbjct 498 SKENKTDYLELPLMEWKALAMATNNFSTDNKLGQGGFGIVYKGMLLDGK----------- 546
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
+ +K L F L++++ H +L + G CV E
Sbjct 547 --------------EIAVKRLSKMSSQGTDEFMNEVRLIAKLQHINLVRLLGCCVDKGEK 592
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGR 738
+++ EY+E+ LD L + + W + + +A L YL ++H ++
Sbjct 593 MLIYEYLENLSLDSHLFDQTRSSNLNWQKRFDIINGIARGLLYLHQDSRCRIIHRDLKAS 652
Query 739 NILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLS 792
N+LL + + K+SD G+ + V +++PE G S
Sbjct 653 NVLLDK-------NMTPKISDFGMARIFGREETEANTRRVVGTYGYMSPEYAMDGI--FS 703
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
D + FG LLEI S +
Sbjct 704 MKSDVFSFGVLLLEIISGKRNKGFYNSNRDLNLL 737
>sp|P29376|LTK_HUMAN Leukocyte tyrosine kinase receptor OS=Homo
sapiens OX=9606 GN=LTK PE=1 SV=3
Length=864
Score = 248 bits (634), Expect = 2e-67, Method: Composition-based stats.
Identities = 89/295 (30%), Positives = 131/295 (44%), Gaps = 34/295 (12%)
Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG G FG+V D + VA+K L C PQ + E I+ H++I++
Sbjct 516 LGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVR 575
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--------SIGLAQLLLFAQQICEGMAY 1013
G + + L E + G ++ +L + + LL AQ I +G Y
Sbjct 576 CVGLSLRATPRLILL--ELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQLAQDIAQGCHY 633
Query 1014 LHAQHYIHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
L H+IHRD+AARN LL R+ KIGDFG+A+ + YYR + PV W P
Sbjct 634 LEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRA-SYYRRGDRALLPVKWMPP 692
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E E F +D WSFGV L+E+ + L + T + + +
Sbjct 693 EAFLEGIFTSKTDSWSFGVLLWEIFS--------------LGYMPYPGRTNQEVLDFVVG 738
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
G R+ P CP VY +M CW+ E RP+F +++ L+ Y Q P V +
Sbjct 739 GGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQ-----YCTQDPDVLN 788
Score = 248 bits (633), Expect = 2e-67, Method: Composition-based stats.
Identities = 84/348 (24%), Positives = 128/348 (37%), Gaps = 51/348 (15%)
Query 552 LPQPGETSNLIIMRGARASPRTL----NLSQLSFH-------RVDQKEITQLSHLGQGTR 600
LP P + + R +P L V +T L LG G
Sbjct 462 LPSPELELSKLRTSAIRTAPNPYYCQVGLGPAQSWPLPPGVTEVSPANVTLLRALGHGAF 521
Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETA 659
VYEG + G D PL +V +K L L F A
Sbjct 522 GEVYEGLV---------IGLPGDSSPL----------QVAIKTLPELCSPQDELDFLMEA 562
Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV----PMAWK--MV 713
++S+ H ++ G+ +R +++ E + G + +LR R H+ P+ + +
Sbjct 563 LIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQ 622
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
+AQ +A YLE + +H ++ RN LL+ G S K+ D G+
Sbjct 623 LAQDIAQGCHYLEENHFIHRDIAARNCLLS----CAGPSRVAKIGDFGMARDIYRASYYR 678
Query 774 ER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
+ W+ PE G ++ D W FG L EI G P R+ E F
Sbjct 679 RGDRALLPVKWMPPEAFLEGI--FTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFV 736
Query 828 QRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
R+ P CP + + +QC +EP RPSF +IL L
Sbjct 737 VGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQYCTQDP 784
>sp|F8W3R9|ALK_DANRE ALK tyrosine kinase receptor OS=Danio rerio
OX=7955 GN=alk PE=2 SV=2
Length=1705
Score = 253 bits (647), Expect = 2e-67, Method: Composition-based stats.
Identities = 75/340 (22%), Positives = 123/340 (36%), Gaps = 40/340 (12%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
V ++ I+ LG G VYEG L V G+P ++V
Sbjct 1104 DLKEVPRRNISLTRGLGHGAFGEVYEG-LAVGIPGEPSP------------------MQV 1144
Query 640 VLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+K L L F A ++S+ SH ++ GV ++ + ++ E + G L +
Sbjct 1145 AVKTLPEVCSEQDELDFLMEALIISKFSHQNIVRCIGVSLQALPHFILLELMAGGDLKSF 1204
Query 699 LRRERGH------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752
LR R + M + +A+ +A YLE +H ++ RN LL +G
Sbjct 1205 LRETRPRLEHPSSLTMVDLLNIARDIARGCQYLEENQFIHRDIAARNCLLT----CKGPG 1260
Query 753 PFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
K+ D G+ + + W+ PE G ++ D W FG L E
Sbjct 1261 RVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPPEAFMEGI--FTSKTDTWSFGVLLWE 1318
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILR 864
I G P SRS E F R+ P +CP + + +Q ++P RP+F TIL
Sbjct 1319 IFSLGYMPYPSRSNQEVLEFVTNGGRMDPPKNCPGPVYRIMTQSWQHQPEDRPNFSTILE 1378
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
+ + + + +
Sbjct 1379 RIDYCLQDPDVVNVPLPVEYGPIPEEEERVPMRPEDPSAP 1418
Score = 249 bits (635), Expect = 6e-66, Method: Composition-based stats.
Identities = 90/344 (26%), Positives = 136/344 (40%), Gaps = 34/344 (10%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
Q P + + + + + +D +R + R LG G FG+V
Sbjct 1071 QSPDCKLSKLRASTIMTDYNPNYCFGGKTASVNDLKEVPRRNISLTRGLGHGAFGEVYEG 1130
Query 915 CYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
+ + VAVK L C Q + E I+ H++I++ G
Sbjct 1131 LAVGIPGEPSPMQVAVKTLPEVCSEQDELDFLMEALIISKFSHQNIVRCIGVSLQALPHF 1190
Query 974 LQLVMEYVPLGSLRDYLPR--------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
+ L E + G L+ +L S+ + LL A+ I G YL +IHRD+A
Sbjct 1191 ILL--ELMAGGDLKSFLRETRPRLEHPSSLTMVDLLNIARDIARGCQYLEENQFIHRDIA 1248
Query 1026 ARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082
ARN LL + KIGDFG+A+ + YYR PV W PE E F +
Sbjct 1249 ARNCLLTCKGPGRVAKIGDFGMARDIYRA-SYYRKGGRAMLPVKWMPPEAFMEGIFTSKT 1307
Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
D WSFGV L+E+ + L + + + E + G R+ P CP
Sbjct 1308 DTWSFGVLLWEIFS--------------LGYMPYPSRSNQEVLEFVTNGGRMDPPKNCPG 1353
Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
VY +M W+ + RP F ++ + Y Q P V +V
Sbjct 1354 PVYRIMTQSWQHQPEDRPNFSTILERID-----YCLQDPDVVNV 1392
>sp|O61122|SVKA_DICDI Serine/threonine-protein kinase svkA OS=Dictyostelium
discoideum OX=44689 GN=svkA PE=1 SV=1
Length=478
Score = 238 bits (608), Expect = 2e-67, Method: Composition-based stats.
Identities = 64/271 (24%), Positives = 116/271 (43%), Gaps = 24/271 (9%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+ +G+G FG+V + N T E +A+K + + +QEI++L
Sbjct 12 YVRQEKIGKGSFGEV----FKGINKKTNETIAIKTIDLEDAEDEIEDIQQEINVLSQCES 67
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016
+ KY G + L ++MEY+ GS+ D + + + +++ +G+ YLH+
Sbjct 68 PFVTKYFGSFLKGSK--LWIIMEYLAGGSVLDLMKPGPFDEGYIAIILRELLKGLEYLHS 125
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ IHRD+ A NVLL VK+ DFG++ + + R FW APE +K+
Sbjct 126 EGKIHRDIKAANVLLSASGDVKLADFGVSGQLTD---QMTKRNTFVGTPFWMAPEVIKQT 182
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+ +D+WS G+T E+ + PP + + +R L+ +
Sbjct 183 GYDSKADIWSMGITALEM-----AKGEPP----------RADLHPMRALFLIPKDPPPTL 227
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
C + + RPT ++L+
Sbjct 228 EGNFSKGFKEFCALCLNKDPNQRPTAKDLLK 258
Score = 200 bits (509), Expect = 4e-54, Method: Composition-based stats.
Identities = 55/297 (19%), Positives = 109/297 (37%), Gaps = 44/297 (15%)
Query 579 LSFHRVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
++ + D +E+ + +G+G+ V++G +
Sbjct 1 MASKKGDPEELYVRQEKIGKGSFGEVFKGINKKTNE------------------------ 36
Query 638 RVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+ +K +D D + +++SQ + G ++G + ++ EY+ G +
Sbjct 37 TIAIKTIDLEDAEDEIEDIQQEINVLSQCESPFVTKYFGSFLKGSKLWIIMEYLAGGSVL 96
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
++ G + ++ ++L L YL ++ +H ++ N+LL+ S +K
Sbjct 97 DLMK--PGPFDEGYIAIILRELLKGLEYLHSEGKIHRDIKAANVLLS-------ASGDVK 147
Query 757 LSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
L+D GV R V W+APE + + D W G T LE+ GE
Sbjct 148 LADFGVSGQLTDQMTKRNTFVGTPFWMAPEVIKQ--TGYDSKADIWSMGITALEMA-KGE 204
Query 813 APLQSRSPSEKEHFYQRQ--HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
P P + L + CL +P QRP+ + +L+
Sbjct 205 PPRADLHPMRALFLIPKDPPPTLEGNFSKGFKEFCALCLNKDPNQRPTAKDLLKHKF 261
>sp|Q8VYA3|WAKLJ_ARATH Wall-associated receptor kinase-like 10
OS=Arabidopsis thaliana OX=3702 GN=WAKL10 PE=2 SV=1
Length=769
Score = 246 bits (628), Expect = 2e-67, Method: Composition-based stats.
Identities = 74/288 (26%), Positives = 118/288 (41%), Gaps = 19/288 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG G V G +VAVK K + E+ IL + H +I+K
Sbjct 439 LGEGGQGTVYKGML-----VDGRIVAVKKSKV-VDEDKLEEFINEVVILSQINHRNIVKL 492
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHA- 1016
GCC + LV E++P G+L ++L S L A I ++YLH+
Sbjct 493 LGCCLETDVP--ILVYEFIPNGNLFEHLHDDSDDYTMTTWEVRLRIAVDIAGALSYLHSA 550
Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
HRD+ + N++LD K+ DFG ++ V H + + V + PE +
Sbjct 551 ASSPIYHRDIKSTNIMLDEKHRAKVSDFGTSRTVTVDHTH--LTTVVSGTVGYMDPEYFQ 608
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+F SDV+SFGV L EL+T S S ++ L M RL+++++ R
Sbjct 609 SSQFTDKSDVYSFGVVLAELITGEKSVSFLRSQEYRTLATYFTLAMKENRLSDIIDARIR 668
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
+ + C + RP+ + L+ + + P
Sbjct 669 DGCKLNQVTAAAKIARKCLNMKGRKRPSMRQVSMELEKIRSYSEDMQP 716
Score = 228 bits (581), Expect = 3e-61, Method: Composition-based stats.
Identities = 69/409 (17%), Positives = 138/409 (34%), Gaps = 70/409 (17%)
Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564
+ E + ++ G SF ++ +G + ++ + G +
Sbjct 349 YTCEYTNHRPLVIGLSTSFSTLVFIGGIYWLYKFIRRQRRLNQKKKFFKRNGGLLLQQQL 408
Query 565 ---RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
G S R N +L + + LG+G + VY+G L
Sbjct 409 TTTEGNVDSTRVFNSRELEK---ATENFSLTRILGEGGQGTVYKGMLVDGRI-------- 457
Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
V +K D F ++SQ++H ++ + G C+
Sbjct 458 -----------------VAVKKSKVVDEDKLEEFINEVVILSQINHRNIVKLLGCCLETD 500
Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAW---KMVVAQQLASALSYLE---NKNLVHGNV 735
I+V E++ +G L L + M ++ +A +A ALSYL + + H ++
Sbjct 501 VPILVYEFIPNGNLFEHLHDDSDDYTMTTWEVRLRIAVDIAGALSYLHSAASSPIYHRDI 560
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANS 790
NI+L K+SD G + + ++ PE ++
Sbjct 561 KSTNIMLDEK-------HRAKVSDFGTSRTVTVDHTHLTTVVSGTVGYMDPEYFQ--SSQ 611
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE------HFYQRQHRLPEPSCPQL--- 841
+ D + FG L E+ GE + E +++RL + ++
Sbjct 612 FTDKSDVYSFGVVLAELI-TGEKSVSFLRSQEYRTLATYFTLAMKENRLSDIIDARIRDG 670
Query 842 ---------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
A + +CL + +RPS R + +L +++ ++
Sbjct 671 CKLNQVTAAAKIARKCLNMKGRKRPSMRQVSMELEKIRSYSEDMQPYEY 719
>sp|C0LGG7|Y1534_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g53420 OS=Arabidopsis thaliana OX=3702
GN=At1g53420 PE=2 SV=2
Length=953
Score = 249 bits (637), Expect = 2e-67, Method: Composition-based stats.
Identities = 73/285 (26%), Positives = 114/285 (40%), Gaps = 19/285 (7%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+GEG FG V G ++AVK L Q + EI ++ L
Sbjct 622 NNFDSANRIGEGGFGPVYKG-----KLFDGTIIAVKQLSTG-SKQGNREFLNEIGMISAL 675
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICE 1009
+H +++K GCC + G+ L LV E+V SL L + + +
Sbjct 676 HHPNLVKLYGCCVEGGQ--LLLVYEFVENNSLARALFGPQETQLRLDWPTRRKICIGVAR 733
Query 1010 GMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G+AYLH + +HRD+ A NVLLD KI DFGLAK E + R G
Sbjct 734 GLAYLHEESRLKIVHRDIKATNVLLDKQLNPKISDFGLAKLDEEDSTHISTRIAG--TFG 791
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLT 1125
+ APE +DV+SFG+ E++ + + LI + L
Sbjct 792 YMAPEYAMRGHLTDKADVYSFGIVALEIVHGRSNKIERSKNNTFYLIDWVEVLREKNNLL 851
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
EL++ + + + C +E RP+ ++ +L+
Sbjct 852 ELVDPRLGSEYNREEAMTMIQIAIMCTSSEPCERPSMSEVVKMLE 896
Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats.
Identities = 67/413 (16%), Positives = 132/413 (32%), Gaps = 70/413 (17%)
Query 518 GWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLS 577
G S ++ L L ++ + + + + AS
Sbjct 559 RNGMSTGTLHTLVVILSIFIVFLVFGTLWKKGYLRSKSQMEKDFKSLELMIAS------F 612
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
L ++ + +G+G VY+G+L
Sbjct 613 SLRQIKIATNNFDSANRIGEGGFGPVYKGKLFDG-------------------------T 647
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+ +K L F ++S + H +L ++G CV G + ++V E+VE+ L
Sbjct 648 IIAVKQLSTGSKQGNREFLNEIGMISALHHPNLVKLYGCCVEGGQLLLVYEFVENNSLAR 707
Query 698 WLRRERG---HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGT 751
L + + + + +A L+YL + +VH ++ N+LL +
Sbjct 708 ALFGPQETQLRLDWPTRRKICIGVARGLAYLHEESRLKIVHRDIKATNVLLDKQLNP--- 764
Query 752 SPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
K+SD G+ + ++APE G L+ D + FG LE
Sbjct 765 ----KISDFGLAKLDEEDSTHISTRIAGTFGYMAPEYAMRG--HLTDKADVYSFGIVALE 818
Query 807 ICFDGEAPLQSRSPSEKEHFYQR------QHRLPEPSCPQLAT------------LTSQC 848
I G + RS + + ++ L E P+L + + C
Sbjct 819 IV-HGRSNKIERSKNNTFYLIDWVEVLREKNNLLELVDPRLGSEYNREEAMTMIQIAIMC 877
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901
+ EP +RPS +++ L + + + + +
Sbjct 878 TSSEPCERPSMSEVVKMLEGKKMVEVEKLEEASVHRETKRLENMNTMKKYYEM 930
>sp|P20806|7LESS_DROVI Protein sevenless OS=Drosophila virilis
OX=7244 GN=sev PE=3 SV=1
Length=2594
Score = 254 bits (648), Expect = 2e-67, Method: Composition-based stats.
Identities = 90/308 (29%), Positives = 144/308 (47%), Gaps = 41/308 (13%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG G FG+V ++ + VA+K+L+ G + QE ++ HE+I+
Sbjct 2229 FLGSGAFGEVYEGQLQAEDEAQPQRVAIKSLRK--GASEFAELLQEAQLMSNFKHENIVC 2286
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQLLLFAQQICEGMA 1012
G C D S+ L+ME++ G L YL + L +LL + G +
Sbjct 2287 LIGICCDTD--SISLIMEHMEAGDLLSYLRAARPSSQEALSKLQLPELLSMCLDVANGCS 2344
Query 1013 YLHAQHYIHRDLAARNVLLDN------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
Y+ H++HRDLA RN L+ + R+VKIGDFGLA+ + + +YYR +G PV
Sbjct 2345 YMEDMHFVHRDLACRNCLVSDGAAIGGRRIVKIGDFGLARDIYKS-DYYRKEGEGLLPVR 2403
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W A E L + F SDVW+FGV +E+ T L +
Sbjct 2404 WMALESLVDGLFSTQSDVWAFGVLCWEIFT--------------LGQQPYAARNNFEVLA 2449
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ-------GQ 1179
++ G RL +P++CP ++Y L+ CW +E RP+F+ + L+ + + +
Sbjct 2450 HVKEGGRLQQPERCPEKLYALLLQCWRSEPWERPSFKRCLSTLQALSSDLRRTEMLATDE 2509
Query 1180 APSVFSVC 1187
P V ++C
Sbjct 2510 TPLVSALC 2517
Score = 252 bits (643), Expect = 9e-67, Method: Composition-based stats.
Identities = 86/333 (26%), Positives = 138/333 (41%), Gaps = 48/333 (14%)
Query 554 QPGETSNLIIMR------GARASPRTLNLSQLS---FHRVDQKEITQLSHLGQGTRTNVY 604
+P SNL ++ AR+ +++LS +++ +T L LG G VY
Sbjct 2180 RPSIWSNLSALQTQQQLLAARSRTFSMSLSDADIALLPQINWNRLTLLRFLGSGAFGEVY 2239
Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664
EG+L+ E D Q RV +K L + A + A LMS
Sbjct 2240 EGQLQAE--------------------DEAQPQRVAIKSLRKGASEFA-ELLQEAQLMSN 2278
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-------HVPMAWKMVVAQQ 717
H ++ + G+C ++ E++E G L +LR R + + + +
Sbjct 2279 FKHENIVCLIGICCDTDSISLIMEHMEAGDLLSYLRAARPSSQEALSKLQLPELLSMCLD 2338
Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE--- 774
+A+ SY+E+ + VH ++ RN L++ G A G +K+ D G+ + +
Sbjct 2339 VANGCSYMEDMHFVHRDLACRNCLVSD-GAAIGGRRIVKIGDFGLARDIYKSDYYRKEGE 2397
Query 775 ---RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
+ W+A E L G ST D W FG EI G+ P +R+ E +
Sbjct 2398 GLLPVRWMALESLVDGL--FSTQSDVWAFGVLCWEIFTLGQQPYAARNNFEVLAHVKEGG 2455
Query 832 RL--PEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
RL PE +L L QC EP +RPSF+
Sbjct 2456 RLQQPERCPEKLYALLLQCWRSEPWERPSFKRC 2488
>sp|F4HRJ4|M3K3A_ARATH Mitogen-activated protein kinase kinase
kinase 3 OS=Arabidopsis thaliana OX=3702 GN=MAPKKK3 PE=1 SV=1
Length=609
Score = 242 bits (618), Expect = 2e-67, Method: Composition-based stats.
Identities = 80/334 (24%), Positives = 137/334 (41%), Gaps = 32/334 (10%)
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919
+ + + + KK + LG G FG+V L
Sbjct 177 SECHPLPRPPTSPTSPSAVHGSRIGGGYETSPSGFSTWKKGKFLGSGTFGQVYLGF---- 232
Query 920 NDGTGEMVAVKALKADCGPQHRSG----WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
N G+M A+K +K Q QEI++L L H +I++Y G + E++L
Sbjct 233 NSEKGKMCAIKEVKVISDDQTSKECLKQLNQEINLLNQLCHPNIVQYYGS--ELSEETLS 290
Query 976 LVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034
+ +EYV GS+ L + S + + +QI G+AYLH ++ +HRD+ N+L+D +
Sbjct 291 VYLEYVSGGSIHKLLKDYGSFTEPVIQNYTRQILAGLAYLHGRNTVHRDIKGANILVDPN 350
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK-EYKFYYASDVWSFGVTLYE 1093
+K+ DFG+AK V + +W APE + + + +A D+WS G T+ E
Sbjct 351 GEIKLADFGMAKHV----TAFSTMLSFKGSPYWMAPEVVMSQNGYTHAVDIWSLGCTILE 406
Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
+ T PP E + + ++ + PD + + ++ C +
Sbjct 407 MAT-----SKPPWSQFEGVA---------AIFKIGNSKDTPEIPDHLSNDAKNFIRLCLQ 452
Query 1154 TEASFRPTFENLI--PILKTVHEKYQGQAPSVFS 1185
+ RPT L+ P L+ P F
Sbjct 453 RNPTVRPTASQLLEHPFLRNTTRVASTSLPKDFP 486
Score = 192 bits (488), Expect = 2e-50, Method: Composition-based stats.
Identities = 58/284 (20%), Positives = 99/284 (35%), Gaps = 35/284 (12%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
+ LG GT VY G +G + V + D +
Sbjct 215 KKGKFLGSGTFGQVYLGFNSEKGKMCAIK-------------------EVKVISDDQTSK 255
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
+ + +L++Q+ H ++ +G + + EYV G + L+ G
Sbjct 256 ECLKQLNQEINLLNQLCHPNIVQYYGSELSEETLSVYLEYVSGGSIHKLLKD-YGSFTEP 314
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+Q+ + L+YL +N VH ++ G NIL+ G IKL+D G+ +
Sbjct 315 VIQNYTRQILAGLAYLHGRNTVHRDIKGANILVDPNGE-------IKLADFGMAKHVTAF 367
Query 770 EERV---ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ W+APE + N + A+D W G T+LE+ + P
Sbjct 368 STMLSFKGSPYWMAPEVVMS-QNGYTHAVDIWSLGCTILEMATS-KPPWSQFEGVAAIFK 425
Query 827 YQRQH---RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+P+ CL PT RP+ +L
Sbjct 426 IGNSKDTPEIPDHLSNDAKNFIRLCLQRNPTVRPTASQLLEHPF 469
>sp|Q00993|UFO_MOUSE Tyrosine-protein kinase receptor UFO OS=Mus
musculus OX=10090 GN=Axl PE=1 SV=2
Length=888
Score = 248 bits (634), Expect = 2e-67, Method: Composition-based stats.
Identities = 84/282 (30%), Positives = 126/282 (45%), Gaps = 29/282 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHII 960
LGEG FG V + D + VAVK +K A C + E ++ H +++
Sbjct 535 TLGEGEFGAVMEGQLN--QDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVM 592
Query 961 KYKGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRHSIGLA-------QLLLFAQQICE 1009
+ G C ++ +++ ++ G L +L +G L+ F I
Sbjct 593 RLIGVCFQGSDREGFPEPVVILPFMKHGDLHSFLLYSRLGDQPVFLPTQMLVKFMADIAS 652
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
GM YL + +IHRDLAARN +L+ + V + DFGL+K + G +YYR PV W A
Sbjct 653 GMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNG-DYYRQGRIAKMPVKWIA 711
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E L + + SDVWSFGVT++E+ T + + + L
Sbjct 712 IESLADRVYTSKSDVWSFGVTMWEIATRGQ--------------TPYPGVENSEIYDYLR 757
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+G RL +P C +Y LM CWE RP+F L L+
Sbjct 758 QGNRLKQPVDCLDGLYALMSRCWELNPRDRPSFAELREDLEN 799
Score = 224 bits (571), Expect = 2e-59, Method: Composition-based stats.
Identities = 68/307 (22%), Positives = 117/307 (38%), Gaps = 52/307 (17%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
+L VD+ ++ LG+G V EG+L + S L
Sbjct 519 KLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSI----------------------L 556
Query 638 RVVLKVLDP--SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEY 689
+V +K + F A M + H ++ + GVC +G PE +++ +
Sbjct 557 KVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSDREGFPEPVVILPF 616
Query 690 VEHGPLDVWLRRERG-----HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
++HG L +L R +P + +AS + YL K +H ++ RN +L
Sbjct 617 MKHGDLHSFLLYSRLGDQPVFLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNE 676
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKW 798
+ + ++D G+ + + + W+A E L ++ D W
Sbjct 677 -------NMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRV--YTSKSDVW 727
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
FG T+ EI G+ P SE + ++ +RL P L L S+C P R
Sbjct 728 SFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPVDCLDGLYALMSRCWELNPRDR 787
Query 857 PSFRTIL 863
PSF +
Sbjct 788 PSFAELR 794
>sp|P55146|TYRO3_RAT Tyrosine-protein kinase receptor TYRO3 OS=Rattus
norvegicus OX=10116 GN=Tyro3 PE=1 SV=1
Length=880
Score = 248 bits (633), Expect = 2e-67, Method: Composition-based stats.
Identities = 87/282 (31%), Positives = 130/282 (46%), Gaps = 28/282 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
LG+G FG V DG+ VAVK LKAD + +E ++ H H+ K
Sbjct 514 LGKGEFGSVREAQLK-QEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAK 572
Query 962 YKGCCED---QGEKSL-QLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEG 1010
G +G + +++ ++ G L +L ++ L L+ F I G
Sbjct 573 LVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLVRFMVDIACG 632
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
M YL ++++IHRDLAARN +L D V + DFGL++ + G +YYR PV W A
Sbjct 633 MEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSG-DYYRQGCASKLPVKWLAL 691
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E L + + SDVW+FGVT++E++T + + L
Sbjct 692 ESLADNLYTVHSDVWAFGVTMWEIMTRGQ--------------TPYAGIENAEIYNYLIS 737
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
G RL +P +C EVY LM CW + RP+F L L+ +
Sbjct 738 GNRLKQPPECMEEVYDLMYQCWSADPKQRPSFTCLRMELENI 779
Score = 234 bits (597), Expect = 9e-63, Method: Composition-based stats.
Identities = 70/316 (22%), Positives = 128/316 (41%), Gaps = 51/316 (16%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
+L + +++ T LG+G +V E +L+ E G +
Sbjct 497 KLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQED---------------------GSFV 535
Query 638 RVVLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEY 689
+V +K+L F A+ M + H H+A + GV +R P +++ +
Sbjct 536 KVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF 595
Query 690 VEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
++HG L +L R ++P+ + +A + YL ++N +H ++ RN +LA
Sbjct 596 MKHGDLHAFLLASRIGENPFNLPLQTLVRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE 655
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKW 798
+ ++D G+ S + + + WLA E L + D W
Sbjct 656 -------DMTVCVADFGLSRKIYSGDYYRQGCASKLPVKWLALESLADNL--YTVHSDVW 706
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
FG T+ EI G+ P +E ++ +RL P ++ L QC + +P QR
Sbjct 707 AFGVTMWEIMTRGQTPYAGIENAEIYNYLISGNRLKQPPECMEEVYDLMYQCWSADPKQR 766
Query 857 PSFRTILRDLTRLQPH 872
PSF + +L + H
Sbjct 767 PSFTCLRMELENILGH 782
>sp|Q9SXB4|Y1130_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g11300 OS=Arabidopsis thaliana OX=3702
GN=At1g11300 PE=2 SV=1
Length=820
Score = 247 bits (630), Expect = 2e-67, Method: Composition-based stats.
Identities = 79/294 (27%), Positives = 122/294 (41%), Gaps = 23/294 (8%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG V G+ +AVK L G Q E+ ++ L H ++
Sbjct 512 RNKLGQGGFGPVYKGKLQE-----GQEIAVKRLSRASG-QGLEELVNEVVVISKLQHRNL 565
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLH 1015
+K GCC E+ LV E++P SL YL + IC G+ YLH
Sbjct 566 VKLLGCCIAGEER--MLVYEFMPKKSLDYYLFDSRRAKLLDWKTRFNIINGICRGLLYLH 623
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
IHRDL A N+LLD + + KI DFGLA+ P + R + APE
Sbjct 624 RDSRLRIIHRDLKASNILLDENLIPKISDFGLARIFPGNEDEANTRR-VVGTYGYMAPEY 682
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
F SDV+S GV L E+++ +S S L+ + L++
Sbjct 683 AMGGLFSEKSDVFSLGVILLEIISGRRNSNST------LLAYVWSIWNEGEINSLVDPEI 736
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT-VHEKYQGQAPSVFS 1185
+K + H+ C + A+ RP+ + +L + + + + + P+ S
Sbjct 737 FDLLFEKEIHKCIHIGLLCVQEAANDRPSVSTVCSMLSSEIADIPEPKQPAFIS 790
Score = 235 bits (600), Expect = 2e-63, Method: Composition-based stats.
Identities = 63/326 (19%), Positives = 109/326 (33%), Gaps = 53/326 (16%)
Query 501 RLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGE--- 557
RL I+ +D +L G + + C+L A R + E
Sbjct 423 RLAHSEIKTKDKRPILIGT-----ILAGGIFVVAACVLLARRIVMKKRAKKKGRDAEQIF 477
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
+ G + + L L + + + LGQG VY+G+L+
Sbjct 478 ERVEALAGGNKGKLKELPLFEFQVLAAATNNFSLRNKLGQGGFGPVYKGKLQEGQ----- 532
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
+ +K L + ++S++ H +L + G C
Sbjct 533 --------------------EIAVKRLSRASGQGLEELVNEVVVISKLQHRNLVKLLGCC 572
Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVH 732
+ G E ++V E++ LD +L R + W + + + L YL ++H
Sbjct 573 IAGEERMLVYEFMPKKSLDYYLFDSRRAKLLDWKTRFNIINGICRGLLYLHRDSRLRIIH 632
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPG 786
++ NILL + K+SD G+ + V ++APE G
Sbjct 633 RDLKASNILLDE-------NLIPKISDFGLARIFPGNEDEANTRRVVGTYGYMAPEYAMG 685
Query 787 GANSLSTAMDKWGFGATLLEICFDGE 812
G S D + G LLEI
Sbjct 686 GL--FSEKSDVFSLGVILLEIISGRR 709
>sp|Q8L710|CRK17_ARATH Cysteine-rich receptor-like protein kinase
17 OS=Arabidopsis thaliana OX=3702 GN=CRK17 PE=2 SV=2
Length=686
Score = 244 bits (623), Expect = 2e-67, Method: Composition-based stats.
Identities = 74/281 (26%), Positives = 112/281 (40%), Gaps = 18/281 (6%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG G FG+V G +AVK L G Q +K E+ ++ L H ++
Sbjct 362 HNKLGAGGFGEVYKGML-----LNGTEIAVKRLSKTSG-QGEIEFKNEVVVVAKLQHINL 415
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015
++ G EK LV E+VP SL +L R+ + I G+ YLH
Sbjct 416 VRLLGFSLQGEEK--LLVYEFVPNKSLDYFLFDPNKRNQLDWTVRRNIIGGITRGILYLH 473
Query 1016 ---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
IHRDL A N+LLD D KI DFG+A+ + +PE
Sbjct 474 QDSRLKIIHRDLKASNILLDADMNPKIADFGMARIFGVDQTVANTAR-VVGTFGYMSPEY 532
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL--ELIGIAQGQMTVLRLTELLER 1130
+ +F SDV+SFGV + E+++ +S L L+ + EL++
Sbjct 533 VTHGQFSMKSDVYSFGVLILEIISGKKNSSFYQMDGLVNNLVTYVWKLWENKTMHELIDP 592
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ H+ C + + RPT + +L T
Sbjct 593 FIKEDCKSDEVIRYVHIGLLCVQENPADRPTMSTIHQVLTT 633
Score = 228 bits (580), Expect = 9e-62, Method: Composition-based stats.
Identities = 70/483 (14%), Positives = 143/483 (30%), Gaps = 93/483 (19%)
Query 433 YLCHEVAPPRLVMSIR-----------DGIHGPLLEPFVQAKLRP----EDGLYLIHWST 477
Y +VAP + +I + L + + G ++ S
Sbjct 189 YYAKDVAPEPVYGNISVVMQCTPDVSSKDCN--LCLERSLDFYKKWYNGKRGTIILRPSC 246
Query 478 SHPYRLILTVAQRSQAPDGMQSLRLRKF-------PIEQQDGAFVLEGWGRSFPSVRELG 530
+R L + + + S S +
Sbjct 247 --FFRWELYTFFGAFDSINARHPPPPPRPLSPPPLKTPSVTNQTNITKKNDSRISGGTIA 304
Query 531 AALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEIT 590
A + ++ L C + + L I+ S + L +
Sbjct 305 AIVVVVVVTIILIVVGLVICKRRKQKQEIELPIVLNEAESVQ----FDLKTIEAATGNFS 360
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ + LG G VY+G L + +K L +
Sbjct 361 EHNKLGAGGFGEVYKGMLLNG-------------------------TEIAVKRLSKTSGQ 395
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--RERGHVPM 708
+ F +++++ H +L + G ++G E ++V E+V + LD +L +R +
Sbjct 396 GEIEFKNEVVVVAKLQHINLVRLLGFSLQGEEKLLVYEFVPNKSLDYFLFDPNKRNQLDW 455
Query 709 AWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL- 764
+ + + + YL ++H ++ NILL K++D G+
Sbjct 456 TVRRNIIGGITRGILYLHQDSRLKIIHRDLKASNILLD-------ADMNPKIADFGMARI 508
Query 765 -----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE----APL 815
+ V +++PE + G S D + FG +LEI + +
Sbjct 509 FGVDQTVANTARVVGTFGYMSPEYVTHG--QFSMKSDVYSFGVLILEIISGKKNSSFYQM 566
Query 816 QSRSPSEKEHFY--QRQHRLPEPSCPQLAT------------LTSQCLTYEPTQRPSFRT 861
+ + + + E P + + C+ P RP+ T
Sbjct 567 DGLVNNLVTYVWKLWENKTMHELIDPFIKEDCKSDEVIRYVHIGLLCVQENPADRPTMST 626
Query 862 ILR 864
I +
Sbjct 627 IHQ 629
>sp|C0LGF4|FEI1_ARATH LRR receptor-like serine/threonine-protein
kinase FEI 1 OS=Arabidopsis thaliana OX=3702 GN=FEI1 PE=1
SV=1
Length=591
Score = 241 bits (616), Expect = 2e-67, Method: Composition-based stats.
Identities = 66/313 (21%), Positives = 136/313 (43%), Gaps = 20/313 (6%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ +S + L + +G G FG V D G++ A+K +
Sbjct 287 MFHGDLPYSSKDIIKKLEMLNEEHIIGCGGFGTVYKLAMD-----DGKVFALKRI-LKLN 340
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995
+++E++IL ++ H +++ +G C K L+ +Y+P GSL + L +
Sbjct 341 EGFDRFFERELEILGSIKHRYLVNLRGYCNSPTSK--LLLYDYLPGGSLDEALHERGEQL 398
Query 996 GLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
+ +G++YLH + IHRD+ + N+LLD + ++ DFGLAK + +
Sbjct 399 DWDSRVNIIIGAAKGLSYLHHDCSPRIIHRDIKSSNILLDGNLEARVSDFGLAKLLEDEE 458
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP-TKFLEL 1111
+ + + APE ++ + +DV+SFGV + E+L+ + + K L +
Sbjct 459 SH--ITTIVAGTFGYLAPEYMQSGRATEKTDVYSFGVLVLEVLSGKRPTDASFIEKGLNV 516
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+G + ++ R ++++ + + + + C RPT ++ +L++
Sbjct 517 VGWLKFLISEKRPRDIVDPNCEGMQ-MESLDALLSIATQCVSPSPEERPTMHRVVQLLES 575
Query 1172 VHEKYQGQAPSVF 1184
+ PS F
Sbjct 576 ---EVMTPCPSEF 585
Score = 192 bits (488), Expect = 2e-50, Method: Composition-based stats.
Identities = 63/397 (16%), Positives = 126/397 (32%), Gaps = 68/397 (17%)
Query 508 EQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGA 567
++ G ++ + GC L ++ G S +++ G
Sbjct 233 KKNSGKLLISASATVGALLLVALMCFWGCFLYKKLGKVEIKSLAKDVGGGAS-IVMFHGD 291
Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
+ +L + + + +G G VY+ MDD
Sbjct 292 LPYSSKDIIKKL-------EMLNEEHIIGCGGFGTVYK-------------LAMDDGKVF 331
Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
LK + + F ++ + H +L + G C +++
Sbjct 332 ------------ALKRILKLNEGFDRFFERELEILGSIKHRYLVNLRGYCNSPTSKLLLY 379
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLAR 744
+Y+ G LD L + ++ + A LSYL + ++H ++ NILL
Sbjct 380 DYLPGGSLDEALHERGEQLDWDSRVNIIIGAAKGLSYLHHDCSPRIIHRDIKSSNILLD- 438
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWG 799
+ ++SD G+ E + +LAPE + G + D +
Sbjct 439 ------GNLEARVSDFGLAKLLEDEESHITTIVAGTFGYLAPEYMQSGRA--TEKTDVYS 490
Query 800 FGATLLEICFDGEAPLQ------SRSPSEKEHFYQRQHRLPEPSCPQ-----------LA 842
FG +LE+ G+ P + F + R + P L
Sbjct 491 FGVLVLEVLS-GKRPTDASFIEKGLNVVGWLKFLISEKRPRDIVDPNCEGMQMESLDALL 549
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
++ +QC++ P +RP+ +++ L
Sbjct 550 SIATQCVSPSPEERPTMHRVVQLLESEVMTPCPSEFY 586
>sp|C0LGG9|Y5344_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g53440 OS=Arabidopsis thaliana OX=3702
GN=At1g53440 PE=2 SV=2
Length=1035
Score = 250 bits (639), Expect = 2e-67, Method: Composition-based stats.
Identities = 78/285 (27%), Positives = 122/285 (43%), Gaps = 19/285 (7%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+GEG FG V G +AVK L + Q + EI ++ L
Sbjct 665 NNFDPENKIGEGGFGPVYKGVL-----ADGMTIAVKQLSSK-SKQGNREFVTEIGMISAL 718
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICE 1009
H +++K GCC + E L LV EY+ SL L R + + I +
Sbjct 719 QHPNLVKLYGCCIEGKE--LLLVYEYLENNSLARALFGTEKQRLHLDWSTRNKVCIGIAK 776
Query 1010 GMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
G+AYLH + +HRD+ A NVLLD KI DFGLAK E + + R G +
Sbjct 777 GLAYLHEESRLKIVHRDIKATNVLLDLSLNAKISDFGLAKLDEEENTHISTRIAG--TIG 834
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHC-DSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+ APE +DV+SFGV E+++ +++ P +F+ L+ A L
Sbjct 835 YMAPEYAMRGYLTDKADVYSFGVVCLEIVSGKSNTNYRPKEEFIYLLDWAYVLQEQGSLL 894
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
EL++ K + ++ C + RP +++ +L+
Sbjct 895 ELVDPDLGTSFSKKEAMRMLNIALLCTNPSPTLRPPMSSVVSMLQ 939
Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats.
Identities = 71/366 (19%), Positives = 123/366 (34%), Gaps = 70/366 (19%)
Query 529 LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKE 588
+ AA L LR E +RG + L Q+ +
Sbjct 613 VIAACVAFGLLV---LVILRLTGYLGGKEVDENEELRGLDLQTGSFTLKQI---KRATNN 666
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+ +G+G VY+G L + + +K L
Sbjct 667 FDPENKIGEGGFGPVYKGVLADG-------------------------MTIAVKQLSSKS 701
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR---RERGH 705
F ++S + H +L ++G C+ G E ++V EY+E+ L L ++R H
Sbjct 702 KQGNREFVTEIGMISALQHPNLVKLYGCCIEGKELLLVYEYLENNSLARALFGTEKQRLH 761
Query 706 VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ + + V +A L+YL + +VH ++ N+LL S K+SD G+
Sbjct 762 LDWSTRNKVCIGIAKGLAYLHEESRLKIVHRDIKATNVLLD-------LSLNAKISDFGL 814
Query 763 GLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ I ++APE G L+ D + FG LEI G++
Sbjct 815 AKLDEEENTHISTRIAGTIGYMAPEYAMRGY--LTDKADVYSFGVVCLEIVS-GKSNTNY 871
Query 818 RSPSEKEHFYQRQHRLPEPSC------------------PQLATLTSQCLTYEPTQRPSF 859
R E + + L E ++ + C PT RP
Sbjct 872 RPKEEFIYLLDWAYVLQEQGSLLELVDPDLGTSFSKKEAMRMLNIALLCTNPSPTLRPPM 931
Query 860 RTILRD 865
+++
Sbjct 932 SSVVSM 937
>sp|Q86IX1|DST1_DICDI Serine/threonine-protein kinase dst1 OS=Dictyostelium
discoideum OX=44689 GN=dst1 PE=3 SV=1
Length=737
Score = 245 bits (625), Expect = 3e-67, Method: Composition-based stats.
Identities = 73/295 (25%), Positives = 127/295 (43%), Gaps = 33/295 (11%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ LG+G FG+V + + G++VA+K + D + ++EI
Sbjct 22 PDDPQTIYHIQERLGKGSFGQV----FKAVHFANGKVVAIKIISLD-DQEAIKDVRKEIS 76
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQIC 1008
IL + +I++Y G + L +VMEY GS+ D L +I ++ L ++
Sbjct 77 ILAECNYPNIVQYFGSYFK--DHQLWIVMEYCGGGSVSDLLQVIDTISEDEIALICREAL 134
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+G+ YLH IHRD+ N+LL++ VK+ DFG++ + + R +W
Sbjct 135 KGLNYLHEFKKIHRDIKGGNILLNDRGEVKLADFGVSAQLF---NTFSKRNTFVGTPYWM 191
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
APE ++E K+ +DVWS G+T E+ + +R+ ++
Sbjct 192 APEVIQENKYDGKADVWSLGITAIEMAEGLPP---------------NSNVHPMRVIFMI 236
Query 1129 ERGERLPRPDK--CPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
R E DK + + C + + RPT + L+ HE Q + P
Sbjct 237 PREESPALTDKSIWSDKFQDFISKCLTKDPAERPTAKELLN-----HEFIQTKKP 286
Score = 202 bits (514), Expect = 7e-53, Method: Composition-based stats.
Identities = 53/283 (19%), Positives = 101/283 (36%), Gaps = 43/283 (15%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
LG+G+ V++ G V +K++ +
Sbjct 33 ERLGKGSFGQVFKAVHFANGK------------------------VVAIKIISLDDQEAI 68
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
+ S++++ ++ ++ G + + +V EY G + L+ +
Sbjct 69 KDVRKEISILAECNYPNIVQYFGSYFKDHQLWIVMEYCGGGSVSDLLQVID-TISEDEIA 127
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS---- 768
++ ++ L+YL +H ++ G NILL G +KL+D GV +
Sbjct 128 LICREALKGLNYLHEFKKIHRDIKGGNILLNDRGE-------VKLADFGVSAQLFNTFSK 180
Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
R V W+APE + N D W G T +E+ +G P + P
Sbjct 181 RNTFVGTPYWMAPEVIQE--NKYDGKADVWSLGITAIEMA-EGLPPNSNVHPMRVIFMIP 237
Query 829 RQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
R+ + S+CLT +P +RP+ + +L
Sbjct 238 REESPALTDKSIWSDKFQDFISKCLTKDPAERPTAKELLNHEF 280
>sp|O23082|CRK44_ARATH Cysteine-rich receptor-like protein kinase
44 OS=Arabidopsis thaliana OX=3702 GN=CRK44 PE=3 SV=2
Length=379
Score = 235 bits (599), Expect = 3e-67, Method: Composition-based stats.
Identities = 69/282 (24%), Positives = 115/282 (41%), Gaps = 18/282 (6%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
LGEG FG V D +GE +AVK L G Q + + E+ ++ L H +
Sbjct 58 PYNHLGEGGFGAVYKGVLD-----SGEEIAVKRLSMKSG-QGDNEFVNEVSLVAKLQHRN 111
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYL 1014
+++ G C E+ L+ E+ SL ++ R + + + G+ YL
Sbjct 112 LVRLLGFCFKGEER--LLIYEFFKNTSLEKFIFDSDRRMILDWEKRYRIISGVARGLLYL 169
Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV-REDGDSPVFWYAP 1070
H IHRD+ A NVLLD+ KI DFG+ K + + AP
Sbjct 170 HEDSHFKIIHRDMKASNVLLDDAMNPKIADFGMVKLFNTDQTSQTMFTSKVAGTYGYMAP 229
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQMTVLRLTELLE 1129
E +F +DV+SFGV + E++ ++ SP + L L+ + +++
Sbjct 230 EYAMSGQFSVKTDVFSFGVLVLEIIKGKKNNWSPEEQSSLFLLSYVWKCWREGEVLNIVD 289
Query 1130 RGERLPR-PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
R + H+ C + RPT +++ +L
Sbjct 290 PSLIETRGLSDEIRKCIHIGLLCVQENPGSRPTMASIVRMLN 331
Score = 219 bits (559), Expect = 6e-62, Method: Composition-based stats.
Identities = 60/322 (19%), Positives = 115/322 (36%), Gaps = 71/322 (22%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
R+ + + +HLG+G VY+G L D G+E
Sbjct 45 DFDTIRLATNDFSPYNHLGEGGFGAVYKGVL-----------------------DSGEE- 80
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+ +K L F SL++++ H +L + G C +G E +++ E+ ++ L+
Sbjct 81 -IAVKRLSMKSGQGDNEFVNEVSLVAKLQHRNLVRLLGFCFKGEERLLIYEFFKNTSLEK 139
Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752
++ + + W + + +A L YL ++H ++ N+LL +
Sbjct 140 FIFDSDRRMILDWEKRYRIISGVARGLLYLHEDSHFKIIHRDMKASNVLLD-------DA 192
Query 753 PFIKLSDPGV--------GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
K++D G+ + + ++APE G S D + FG +
Sbjct 193 MNPKIADFGMVKLFNTDQTSQTMFTSKVAGTYGYMAPEYAMSG--QFSVKTDVFSFGVLV 250
Query 805 LEICFDGEAPLQSRSPSEKEHF--------YQRQHRLPEPSCPQLAT------------- 843
LEI + + SP E+ R+ + P L
Sbjct 251 LEIIKGKK---NNWSPEEQSSLFLLSYVWKCWREGEVLNIVDPSLIETRGLSDEIRKCIH 307
Query 844 LTSQCLTYEPTQRPSFRTILRD 865
+ C+ P RP+ +I+R
Sbjct 308 IGLLCVQENPGSRPTMASIVRM 329
>sp|O64793|Y1675_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g67520 OS=Arabidopsis thaliana OX=3702
GN=At1g67520 PE=2 SV=3
Length=818
Score = 247 bits (630), Expect = 3e-67, Method: Composition-based stats.
Identities = 77/281 (27%), Positives = 120/281 (43%), Gaps = 23/281 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LGEG FG V GE VA+K L G Q +K E ++ L H +++
Sbjct 500 NKLGEGGFGPVYKG-----KLLNGEEVAIKRLSLASG-QGLVEFKNEAILIAKLQHTNLV 553
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSL----RDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016
+ GCC ++ EK L+ EY+ SL D L ++ + + I +G+ YLH
Sbjct 554 QVLGCCIEKDEK--MLIYEYMQNKSLDYFLFDPLRKNVLDWTLRFRIMEGIIQGLLYLHK 611
Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRD+ A N+LLD D KI DFGLA+ + + +PE
Sbjct 612 YSRLKVIHRDIKASNILLDEDMNPKISDFGLARIFGAEETRANTKRVA-GTFGYMSPEYF 670
Query 1074 KEYKFYYASDVWSFGVTLYELLTHC--DSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+E F SDV+SFGV + E++ +S L LI ++ E+++
Sbjct 671 REGLFSAKSDVFSFGVLMLEIICGRKNNSFHHDLEGPLNLIVHVWNLFKENKIREVIDLS 730
Query 1132 ER---LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
R L P + C + A RP+ +++ ++
Sbjct 731 LRDSALDYPQ--VLRCVQVALLCVQENAEDRPSMLDVVSMI 769
Score = 227 bits (579), Expect = 1e-60, Method: Composition-based stats.
Identities = 52/280 (19%), Positives = 96/280 (34%), Gaps = 45/280 (16%)
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
R R S L + + + + LG+G VY+G+L
Sbjct 472 RNERKSNNELQIFSFESVVSATDDFSDENKLGEGGFGPVYKGKLLNGE------------ 519
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
V +K L + + F A L++++ HT+L V G C+ E +
Sbjct 520 -------------EVAIKRLSLASGQGLVEFKNEAILIAKLQHTNLVQVLGCCIEKDEKM 566
Query 685 MVTEYVEHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRN 739
++ EY+++ LD +L + + + + + + L YL ++H ++ N
Sbjct 567 LIYEYMQNKSLDYFLFDPLRKNVLDWTLRFRIMEGIIQGLLYLHKYSRLKVIHRDIKASN 626
Query 740 ILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLST 793
ILL K+SD G+ + + +++PE G S
Sbjct 627 ILLDE-------DMNPKISDFGLARIFGAEETRANTKRVAGTFGYMSPEYFREGL--FSA 677
Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833
D + FG +LEI + + L
Sbjct 678 KSDVFSFGVLMLEIICGRKNNSFHHDLEGPLNLIVHVWNL 717
>sp|Q9LDN1|CRK33_ARATH Putative cysteine-rich receptor-like protein
kinase 33 OS=Arabidopsis thaliana OX=3702 GN=CRK33 PE=3
SV=1
Length=636
Score = 243 bits (619), Expect = 3e-67, Method: Composition-based stats.
Identities = 71/286 (25%), Positives = 112/286 (39%), Gaps = 18/286 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
K LG+G FG+V G +AVK L + Q ++ E ++ L
Sbjct 319 CTFSKCNMLGQGGFGEVFKGVLQ-----DGSEIAVKRLSKE-SAQGVQEFQNETSLVAKL 372
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEG 1010
H +++ G C + EK LV E+VP SL +L + + A+ G
Sbjct 373 QHRNLVGVLGFCMEGEEK--ILVYEFVPNKSLDQFLFEPTKKGQLDWAKRYKIIVGTARG 430
Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH IHRDL A N+LLD + K+ DFG+A+ R +
Sbjct 431 ILYLHHDSPLKIIHRDLKASNILLDAEMEPKVADFGMARIFRVDQSRADTRR-VVGTHGY 489
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLT 1125
+PE L +F SDV+SFGV + E+++ + L+ A
Sbjct 490 ISPEYLMHGQFSVKSDVYSFGVLVLEIISGKRNSNFHETDESGKNLVTYAWRHWRNGSPL 549
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
EL++ H+ C + + RP +I +L +
Sbjct 550 ELVDSELEKNYQSNEVFRCIHIALLCVQNDPEQRPNLSTIIMMLTS 595
Score = 227 bits (579), Expect = 6e-62, Method: Composition-based stats.
Identities = 63/326 (19%), Positives = 110/326 (34%), Gaps = 63/326 (19%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
SP+ L ++ + LGQG V++G L+
Sbjct 301 ESPKYSLQYDLKTIEAATCTFSKCNMLGQGGFGEVFKGVLQDGS---------------- 344
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+ +K L F SL++++ H +L V G C+ G E I+V E
Sbjct 345 ---------EIAVKRLSKESAQGVQEFQNETSLVAKLQHRNLVGVLGFCMEGEEKILVYE 395
Query 689 YVEHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLA 743
+V + LD +L ++G + A + + A + YL + ++H ++ NILL
Sbjct 396 FVPNKSLDQFLFEPTKKGQLDWAKRYKIIVGTARGILYLHHDSPLKIIHRDLKASNILLD 455
Query 744 RLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDK 797
K++D G+ V +++PE L G S D
Sbjct 456 AEMEP-------KVADFGMARIFRVDQSRADTRRVVGTHGYISPEYLMHG--QFSVKSDV 506
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------------ 839
+ FG +LEI + ++ R P
Sbjct 507 YSFGVLVLEIISGKRNSNFHETDESGKNLVTYAWRHWRNGSPLELVDSELEKNYQSNEVF 566
Query 840 QLATLTSQCLTYEPTQRPSFRTILRD 865
+ + C+ +P QRP+ TI+
Sbjct 567 RCIHIALLCVQNDPEQRPNLSTIIMM 592
>sp|Q9C5S9|CRK6_ARATH Cysteine-rich receptor-like protein kinase
6 OS=Arabidopsis thaliana OX=3702 GN=CRK6 PE=1 SV=1
Length=674
Score = 243 bits (621), Expect = 3e-67, Method: Composition-based stats.
Identities = 74/279 (27%), Positives = 119/279 (43%), Gaps = 17/279 (6%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G FG+V + G+ VAVK L + Q + +K E+ ++ L H +++
Sbjct 355 NKIGRGGFGEVYKGTF-----SNGKEVAVKRLSKN-SRQGEAEFKTEVVVVAKLQHRNLV 408
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016
+ G QGE+ + LV EY+P SL L + + Q I G+ YLH
Sbjct 409 RLLG-FSLQGEERI-LVYEYMPNKSLDCLLFDPTKQIQLDWMQRYNIIGGIARGILYLHQ 466
Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRDL A N+LLD D KI DFG+A+ + APE
Sbjct 467 DSRLTIIHRDLKASNILLDADINPKIADFGMARIFGLDQTQDNTSR-IVGTYGYMAPEYA 525
Query 1074 KEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+F SDV+SFGV + E+++ +SS +L+ A T + +L++
Sbjct 526 MHGQFSMKSDVYSFGVLVLEIISGRKNSSFGESDGAQDLLTHAWRLWTNKKALDLVDPLI 585
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ H+ C + + + RP + +L +
Sbjct 586 AENCQNSEVVRCIHIGLLCVQEDPAKRPAISTVFMMLTS 624
Score = 231 bits (590), Expect = 4e-63, Method: Composition-based stats.
Identities = 59/358 (16%), Positives = 112/358 (31%), Gaps = 66/358 (18%)
Query 578 QLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
QL + + + + + +G+G VY+G
Sbjct 338 QLDYRTIQTATNDFAESNKIGRGGFGEVYKGTFSNGK----------------------- 374
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K L + F +++++ H +L + G ++G E I+V EY+ + L
Sbjct 375 --EVAVKRLSKNSRQGEAEFKTEVVVVAKLQHRNLVRLLGFSLQGEERILVYEYMPNKSL 432
Query 696 DVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEG 750
D L + + W + + +A + YL + ++H ++ NILL
Sbjct 433 DCLLFDPTKQIQLDWMQRYNIIGGIARGILYLHQDSRLTIIHRDLKASNILLD------- 485
Query 751 TSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
K++D G+ + V ++APE G S D + FG +
Sbjct 486 ADINPKIADFGMARIFGLDQTQDNTSRIVGTYGYMAPEYAMHG--QFSMKSDVYSFGVLV 543
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLP------EPSCPQLAT------------LTS 846
LEI + S + RL + P +A +
Sbjct 544 LEIISGRKNSSFGES-DGAQDLLTHAWRLWTNKKALDLVDPLIAENCQNSEVVRCIHIGL 602
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
C+ +P +RP+ T+ LT + +
Sbjct 603 LCVQEDPAKRPAISTVFMMLTSNTVTLPVPRQPGFFIQCRAVKDPLDSDQSTTTKSFP 660
>sp|P14617|INSRR_CAVPO Insulin receptor-related protein OS=Cavia
porcellus OX=10141 GN=INSRR PE=3 SV=1
Length=1300
Score = 252 bits (643), Expect = 3e-67, Method: Composition-based stats.
Identities = 92/321 (29%), Positives = 148/321 (46%), Gaps = 32/321 (10%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT-GEMVAV 929
++ D D + + IR+LG+G FG V G VA+
Sbjct 953 YTSVNPEYLSASDMYIPDEWEVPREQISIIRELGQGSFGMVYEGVAKGLEAGEESTPVAL 1012
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K + P+ R + +E +++ H+++ G QG+ +L ++ME + G L+ +
Sbjct 1013 KTVNELASPRERIEFLKEASVMKAFQCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSH 1070
Query 990 LPR-----------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
L L ++ A +I +GMAYL A ++HRDLAARN ++ D VK
Sbjct 1071 LRSLRPEAENNPGIPRPALGDMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVK 1130
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
IGDFG+ + V E +YYR G PV W APE LK+ F SDVWSFGV L+E++T
Sbjct 1131 IGDFGMTRDVYE-TDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVT-- 1187
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
L ++ ++ + + G L + CP ++ LM +CW+
Sbjct 1188 ------------LAEQPYQGLSNEQVLKFVMDGGVLEELEDCPHQLQELMSSCWQQNPRL 1235
Query 1159 RPTFENLIPILKTVHEKYQGQ 1179
RPTF + L ++ ++ +
Sbjct 1236 RPTFTQI---LNSIQKELRPS 1253
Score = 243 bits (619), Expect = 3e-64, Method: Composition-based stats.
Identities = 75/344 (22%), Positives = 129/344 (38%), Gaps = 49/344 (14%)
Query 567 ARASPRTLNLSQL---SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
+P L+ S + V +++I+ + LGQG+ VYEG + +G+
Sbjct 954 TSVNPEYLSASDMYIPDEWEVPREQISIIRELGQGSFGMVYEGVAKGLEAGE-------- 1005
Query 624 EDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
+ V LK ++ + + F + AS+M H+ + GV +G
Sbjct 1006 -----------ESTPVALKTVNELASPRERIEFLKEASVMKAFQCHHVVRLLGVVSQGQP 1054
Query 683 NIMVTEYVEHGPLDVWLRRERGHVP---------MAWKMVVAQQLASALSYLENKNLVHG 733
+++ E + G L LR R + + +A ++A ++YL VH
Sbjct 1055 TLVIMELMTRGDLKSHLRSLRPEAENNPGIPRPALGDMIQMAGEIADGMAYLAANKFVHR 1114
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGG 787
++ RN ++++ +K+ D G+ + + + W+APE L G
Sbjct 1115 DLAARNCMVSQ-------DFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDG 1167
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCPQ-LATLT 845
+T D W FG L EI E P Q S + F L E CP L L
Sbjct 1168 I--FTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEDCPHQLQELM 1225
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
S C P RP+F IL + + + + +
Sbjct 1226 SSCWQQNPRLRPTFTQILNSIQKELRPSFRLLSFYHSPECQGGC 1269
>sp|Q8RX80|CRK18_ARATH Cysteine-rich receptor-like protein kinase
18 OS=Arabidopsis thaliana OX=3702 GN=CRK18 PE=2 SV=2
Length=659
Score = 243 bits (620), Expect = 3e-67, Method: Composition-based stats.
Identities = 73/281 (26%), Positives = 110/281 (39%), Gaps = 18/281 (6%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG+V G +AVK L G +K E+ ++ L H ++
Sbjct 342 RNKLGKGGFGEVYKGMLM-----NGTEIAVKRLSKTSGQGEVE-FKNEVVVVAKLQHINL 395
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015
++ G EK LV E+V SL +L R+ + I G+ YLH
Sbjct 396 VRLLGFSLQGEEK--LLVYEFVSNKSLDYFLFDPTKRNQLDWTMRRNIIGGITRGILYLH 453
Query 1016 ---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
IHRDL A N+LLD D KI DFG+A+ + +PE
Sbjct 454 QDSRLKIIHRDLKASNILLDADMNPKIADFGMARIFGVDQTVANT-GRVVGTFGYMSPEY 512
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL--ELIGIAQGQMTVLRLTELLER 1130
+ +F SDV+SFGV + E+++ +S L L+ L ELL+
Sbjct 513 VTHGQFSMKSDVYSFGVLILEIISGKKNSSFYQMDGLVNNLVTYVWKLWENKSLHELLDP 572
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ H+ C + + RPT + +L
Sbjct 573 FINQDFTSEEVIRYIHIGLLCVQENPADRPTMSTIHQMLTN 613
Score = 230 bits (586), Expect = 1e-62, Method: Composition-based stats.
Identities = 58/360 (16%), Positives = 114/360 (32%), Gaps = 47/360 (13%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
SN + P L ++ + LG+G VY+G L
Sbjct 308 ISNRRKQKQEMDLPTESVQFDLKTIESATSNFSERNKLGKGGFGEVYKGMLMNG------ 361
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
+ +K L + + F +++++ H +L + G
Sbjct 362 -------------------TEIAVKRLSKTSGQGEVEFKNEVVVVAKLQHINLVRLLGFS 402
Query 678 VRGPENIMVTEYVEHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENK---NLVH 732
++G E ++V E+V + LD +L +R + + + + + YL ++H
Sbjct 403 LQGEEKLLVYEFVSNKSLDYFLFDPTKRNQLDWTMRRNIIGGITRGILYLHQDSRLKIIH 462
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPG 786
++ NILL K++D G+ + V +++PE +
Sbjct 463 RDLKASNILLD-------ADMNPKIADFGMARIFGVDQTVANTGRVVGTFGYMSPEYVTH 515
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTS 846
G S D + FG +LEI + + + +L E L L
Sbjct 516 G--QFSMKSDVYSFGVLILEIISGKKNSSFYQMDGLVNNLVTYVWKLWENKS--LHELLD 571
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ + T R I L +Q + ++ ++ L G
Sbjct 572 PFINQDFTSEEVIRYIHIGLLCVQENPADRPTMSTIHQMLTNSSITLPVPLPPGFFFRNG 631
>sp|Q9VZI2|ACK_DROME Activated Cdc42 kinase Ack OS=Drosophila
melanogaster OX=7227 GN=Ack PE=1 SV=2
Length=1073
Score = 250 bits (639), Expect = 3e-67, Method: Composition-based stats.
Identities = 95/287 (33%), Positives = 146/287 (51%), Gaps = 20/287 (7%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQE 947
+ H++ + LG+G FG V + + G VAVK LK+D P + +E
Sbjct 116 CLIHEKDITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFRE 175
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQ 1005
+ + L H ++++ G Q + ++ E GSL D L + L + ++
Sbjct 176 VQAMHALDHANLVRLYGVVLSQ---PMMMITELAERGSLLDTLRKQCRHTSLTIIWNWSV 232
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
QI GMAYL + ++HRDLA RNVLL +KIGDFGL +A+P+ + Y + E P
Sbjct 233 QIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPF 292
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
W APE L+ +F +ASD W FGVTL+E+ + + +G+ Q+ L
Sbjct 293 PWCAPESLRFRQFSHASDTWMFGVTLWEMFSFGEDP---------WVGLNGSQI----LR 339
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
++ GERL +PD CP +VY +M CW+ + RPTF L L ++
Sbjct 340 KIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYLASM 386
Score = 221 bits (562), Expect = 1e-57, Method: Composition-based stats.
Identities = 96/427 (22%), Positives = 154/427 (36%), Gaps = 58/427 (14%)
Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
D +Q RL F D LE G P++R L A++ R+ L +
Sbjct 36 DDLQVTRLAHFDYVLPDD---LERCGLGKPAIRRLMEAVRKKK------AHQWRKNILSK 86
Query 555 ----PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRV 610
+ S+ AR S + + +K+IT LG G+ V G
Sbjct 87 LIGGGKQPSSKKQSSAARESSQGNGTQLTCL--IHEKDITMGLKLGDGSFGVVRRGEW-- 142
Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH---HDIALAFYETASLMSQVSH 667
G+ + V +KVL + I F+ M + H
Sbjct 143 ------------------SASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHALDH 184
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
+L ++GV + +M+TE E G L LR++ H + + Q+ + ++YLE
Sbjct 185 ANLVRLYGVVL-SQPMMMITELAERGSLLDTLRKQCRHTSLTIIWNWSVQIVTGMAYLEQ 243
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-------ALSREERVERIPWLA 780
K +H ++ RN+LLA IK+ D G+ + E + PW A
Sbjct 244 KRFLHRDLACRNVLLAAGN-------KIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCA 296
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRL--PEPS 837
PE L S A D W FG TL E+ GE P + S+ + RL P+
Sbjct 297 PESLR--FRQFSHASDTWMFGVTLWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDAC 354
Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897
P + + QC P +RP+F + L + P + + + +
Sbjct 355 PPDVYAMMLQCWDKTPAERPTFAALKEYLASMSPPVMRASRSHHESKGLQIEPGDTIAII 414
Query 898 KKIRDLG 904
+L
Sbjct 415 DGRHELK 421
>sp|P55144|TYRO3_MOUSE Tyrosine-protein kinase receptor TYRO3
OS=Mus musculus OX=10090 GN=Tyro3 PE=1 SV=2
Length=880
Score = 248 bits (632), Expect = 3e-67, Method: Composition-based stats.
Identities = 87/282 (31%), Positives = 130/282 (46%), Gaps = 28/282 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
LG+G FG V DG+ VAVK LKAD + +E ++ H H+ K
Sbjct 514 LGKGEFGSVREAQLK-QEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAK 572
Query 962 YKGCCED---QGEKSL-QLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEG 1010
G +G + +++ ++ G L +L ++ L L+ F I G
Sbjct 573 LVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLVRFMVDIACG 632
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
M YL ++++IHRDLAARN +L D V + DFGL++ + G +YYR PV W A
Sbjct 633 MEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSG-DYYRQGCASKLPVKWLAL 691
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E L + + SDVW+FGVT++E++T + + L
Sbjct 692 ESLADNLYTVHSDVWAFGVTMWEIMTRGQ--------------TPYAGIENAEIYNYLIG 737
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
G RL +P +C EVY LM CW + RP+F L L+ +
Sbjct 738 GNRLKQPPECMEEVYDLMYQCWSADPKQRPSFTCLRMELENI 779
Score = 234 bits (597), Expect = 1e-62, Method: Composition-based stats.
Identities = 70/316 (22%), Positives = 128/316 (41%), Gaps = 51/316 (16%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
+L + +++ T LG+G +V E +L+ E G +
Sbjct 497 KLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQED---------------------GSFV 535
Query 638 RVVLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEY 689
+V +K+L F A+ M + H H+A + GV +R P +++ +
Sbjct 536 KVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF 595
Query 690 VEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
++HG L +L R ++P+ + +A + YL ++N +H ++ RN +LA
Sbjct 596 MKHGDLHAFLLASRIGENPFNLPLQTLVRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE 655
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKW 798
+ ++D G+ S + + + WLA E L + D W
Sbjct 656 -------DMTVCVADFGLSRKIYSGDYYRQGCASKLPVKWLALESLADNL--YTVHSDVW 706
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
FG T+ EI G+ P +E ++ +RL P ++ L QC + +P QR
Sbjct 707 AFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQPPECMEEVYDLMYQCWSADPKQR 766
Query 857 PSFRTILRDLTRLQPH 872
PSF + +L + H
Sbjct 767 PSFTCLRMELENILGH 782
>sp|Q9T058|Y4119_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At4g11900 OS=Arabidopsis thaliana OX=3702
GN=At4g11900 PE=2 SV=1
Length=849
Score = 247 bits (631), Expect = 3e-67, Method: Composition-based stats.
Identities = 71/332 (21%), Positives = 120/332 (36%), Gaps = 17/332 (5%)
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
C +R + + L L D N + + + LGEG
Sbjct 488 CCISSRIRRKKKQRDEKHSRELLEGGLIDDAGENMCYLNLHDIMVATNSFSRKKKLGEGG 547
Query 908 FGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
FG V G VA+K L Q + +K E+ ++ L H+++++ G C
Sbjct 548 FGPVYKG-----KLPNGMEVAIKRLSKKSS-QGLTEFKNEVVLIIKLQHKNLVRLLGYCV 601
Query 968 DQGEKSLQLVMEYVPL----GSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA---QHYI 1020
+ EK L+ EY+ G L D L + + G+ YLH I
Sbjct 602 EGDEK--LLIYEYMSNKSLDGLLFDSLKSRELDWETRMKIVNGTTRGLQYLHEYSRLRII 659
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDL A N+LLD++ KI DFG A+ + + + +PE
Sbjct 660 HRDLKASNILLDDEMNPKISDFGTARIFG-CKQIDDSTQRIVGTFGYMSPEYALGGVISE 718
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFL-ELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SD++SFGV L E+++ +++ LI + +++ +
Sbjct 719 KSDIYSFGVLLLEIISGKKATRFVHNDQKHSLIAYEWESWCETKGVSIIDEPMCCSYSLE 778
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
H+ C + RP ++ +L
Sbjct 779 EAMRCIHIALLCVQDHPKDRPMISQIVYMLSN 810
Score = 244 bits (623), Expect = 3e-66, Method: Composition-based stats.
Identities = 74/383 (19%), Positives = 119/383 (31%), Gaps = 74/383 (19%)
Query 519 WGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL--------PQPGETSNLIIMRGARAS 570
+ + L L A CF CC+ Q E + ++ G
Sbjct 457 RKTEHSKGKSIVLPLVLASLVATAACFVGLYCCISSRIRRKKKQRDEKHSRELLEGGLID 516
Query 571 PRTLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
N+ L+ H + ++ LG+G VY+G+L
Sbjct 517 DAGENMCYLNLHDIMVATNSFSRKKKLGEGGFGPVYKGKLPNG----------------- 559
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+ V +K L F L+ ++ H +L + G CV G E +++ E
Sbjct 560 --------MEVAIKRLSKKSSQGLTEFKNEVVLIIKLQHKNLVRLLGYCVEGDEKLLIYE 611
Query 689 YVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLA 743
Y+ + LD L + W +M + L YL ++H ++ NILL
Sbjct 612 YMSNKSLDGLLFDSLKSRELDWETRMKIVNGTTRGLQYLHEYSRLRIIHRDLKASNILLD 671
Query 744 RLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDK 797
K+SD G S + V +++PE GG +S D
Sbjct 672 -------DEMNPKISDFGTARIFGCKQIDDSTQRIVGTFGYMSPEYALGGV--ISEKSDI 722
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL------------PEPSCPQLATLT 845
+ FG LLEI G+ + +K + P L
Sbjct 723 YSFGVLLLEIIS-GKKATRFVHNDQKHSLIAYEWESWCETKGVSIIDEPMCCSYSLEEAM 781
Query 846 S------QCLTYEPTQRPSFRTI 862
C+ P RP I
Sbjct 782 RCIHIALLCVQDHPKDRPMISQI 804
>sp|Q06418|TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3
OS=Homo sapiens OX=9606 GN=TYRO3 PE=1 SV=1
Length=890
Score = 248 bits (633), Expect = 3e-67, Method: Composition-based stats.
Identities = 86/282 (30%), Positives = 130/282 (46%), Gaps = 28/282 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
LG+G FG V DG+ VAVK LKAD + +E ++ H H+ K
Sbjct 524 LGKGEFGSVREAQLK-QEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAK 582
Query 962 YKGCCED---QGEKSL-QLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEG 1010
G +G + +++ ++ G L +L ++ L L+ F I G
Sbjct 583 LVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLIRFMVDIACG 642
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
M YL ++++IHRDLAARN +L D V + DFGL++ + G +YYR PV W A
Sbjct 643 MEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSG-DYYRQGCASKLPVKWLAL 701
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E L + + SDVW+FGVT++E++T + + L
Sbjct 702 ESLADNLYTVQSDVWAFGVTMWEIMTRGQ--------------TPYAGIENAEIYNYLIG 747
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
G RL +P +C +VY LM CW + RP+F L L+ +
Sbjct 748 GNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMELENI 789
Score = 234 bits (597), Expect = 1e-62, Method: Composition-based stats.
Identities = 69/313 (22%), Positives = 126/313 (40%), Gaps = 51/313 (16%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
+L + +++ T LG+G +V E +L+ E G +
Sbjct 507 KLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQED---------------------GSFV 545
Query 638 RVVLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEY 689
+V +K+L F A+ M + H H+A + GV +R P +++ +
Sbjct 546 KVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF 605
Query 690 VEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
++HG L +L R ++P+ + +A + YL ++N +H ++ RN +LA
Sbjct 606 MKHGDLHAFLLASRIGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE 665
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKW 798
+ ++D G+ S + + + WLA E L + D W
Sbjct 666 -------DMTVCVADFGLSRKIYSGDYYRQGCASKLPVKWLALESLADNL--YTVQSDVW 716
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
FG T+ EI G+ P +E ++ +RL P + L QC + +P QR
Sbjct 717 AFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQPPECMEDVYDLMYQCWSADPKQR 776
Query 857 PSFRTILRDLTRL 869
PSF + +L +
Sbjct 777 PSFTCLRMELENI 789
>sp|C0LGQ7|Y4245_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At4g20450 OS=Arabidopsis thaliana OX=3702
GN=At4g20450 PE=1 SV=1
Length=898
Score = 248 bits (633), Expect = 3e-67, Method: Composition-based stats.
Identities = 77/299 (26%), Positives = 128/299 (43%), Gaps = 17/299 (6%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
+ + + R LGEG FG V N E VAVK L ++ Q
Sbjct 574 MVANKRSYTYEEVAVITNNFERPLGEGGFGVVYHG-----NVNDNEQVAVKVL-SESSAQ 627
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSI 995
+K E+D+L ++H +++ G C++ + L L+ EY+ G+L+ +L R +
Sbjct 628 GYKQFKAEVDLLLRVHHINLVTLVGYCDEG--QHLVLIYEYMSNGNLKQHLSGENSRSPL 685
Query 996 GLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
L A + +G+ YLH IHRD+ + N+LLDN+ K+GDFGL+++ P G
Sbjct 686 SWENRLRIAAETAQGLEYLHIGCKPPMIHRDIKSMNILLDNNFQAKLGDFGLSRSFPVGS 745
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
E + SP + PE + SDV+SFGV L E++T K +
Sbjct 746 ETHVSTNVAGSP-GYLDPEYYRTNWLTEKSDVFSFGVVLLEIITSQPVIDQTREK-SHIG 803
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
++T + +++ + L +C +S RP + L+
Sbjct 804 EWVGFKLTNGDIKNIVDPSMNGDYDSSSLWKALELAMSCVSPSSSGRPNMSQVANELQE 862
Score = 213 bits (542), Expect = 1e-55, Method: Composition-based stats.
Identities = 70/330 (21%), Positives = 110/330 (33%), Gaps = 60/330 (18%)
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
A S N ++ V LG+G VY G +
Sbjct 568 KASRSSMVANKRSYTYEEVAVITNNFERPLGEGGFGVVYHGNVNDNE------------- 614
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
+V +KVL S F L+ +V H +L + G C G ++
Sbjct 615 ------------QVAVKVLSESSAQGYKQFKAEVDLLLRVHHINLVTLVGYCDEGQHLVL 662
Query 686 VTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNI 740
+ EY+ +G L L E P++W ++ +A + A L YL ++H ++ NI
Sbjct 663 IYEYMSNGNLKQHLSGENSRSPLSWENRLRIAAETAQGLEYLHIGCKPPMIHRDIKSMNI 722
Query 741 LLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVER-----IPWLAPECLPGGANSLSTA 794
LL + KL D G+ + E V +L PE N L+
Sbjct 723 LLDN-------NFQAKLGDFGLSRSFPVGSETHVSTNVAGSPGYLDPEYYRT--NWLTEK 773
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPS---EKEHFYQRQHRLPEPSCPQLA--------- 842
D + FG LLEI Q+R S E F + P +
Sbjct 774 SDVFSFGVVLLEIITSQPVIDQTREKSHIGEWVGFKLTNGDIKNIVDPSMNGDYDSSSLW 833
Query 843 ---TLTSQCLTYEPTQRPSFRTILRDLTRL 869
L C++ + RP+ + +L
Sbjct 834 KALELAMSCVSPSSSGRPNMSQVANELQEC 863
>sp|Q9LZF8|PCRK2_ARATH Serine/threonine-protein kinase PCRK2 OS=Arabidopsis
thaliana OX=3702 GN=PCRK2 PE=1 SV=1
Length=420
Score = 236 bits (602), Expect = 3e-67, Method: Composition-based stats.
Identities = 75/283 (27%), Positives = 126/283 (45%), Gaps = 13/283 (5%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG FG V D + ++ VAVK L G Q W E++ L + H +++K
Sbjct 87 IGEGGFGCVFWGTIKNLEDPSKKIEVAVKQL-GKRGLQGHKEWVTEVNFLGVVEHSNLVK 145
Query 962 YKGCCEDQGEKSL--QLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA 1016
G C + E+ + LV EY+P S+ +L S + L AQ G+ YLH
Sbjct 146 LLGHCAEDDERGIQRLLVYEYMPNQSVEFHLSPRSPTVLTWDLRLRIAQDAARGLTYLHE 205
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ I RD + N+LLD + K+ DFGLA+ P + V D + + APE +
Sbjct 206 EMDFQIIFRDFKSSNILLDENWTAKLSDFGLARLGPSPGSSH-VSTDVVGTMGYAAPEYI 264
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMT-VLRLTELLERG 1131
+ + SDVW +GV +YEL+T ++ P +L+ + ++ R +++
Sbjct 265 QTGRLTSKSDVWGYGVFIYELITGRRPLDRNKPKGEQKLLEWVRPYLSDTRRFRLIVDPR 324
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
K ++ + C A RP ++ ++ + E
Sbjct 325 LEGKYMIKSVQKLAVVANLCLTRNAKARPKMSEVLEMVTKIVE 367
Score = 211 bits (538), Expect = 1e-58, Method: Composition-based stats.
Identities = 72/389 (19%), Positives = 135/389 (35%), Gaps = 64/389 (16%)
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGS 613
S+ S R NL + + + + ++ +G+G V+ G ++
Sbjct 46 STVSSTGRNSNTSMSARENNLREFTIGDLKSATRNFSRSGMIGEGGFGCVFWGTIKNL-- 103
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
D +++ V +K L + + + V H++L +
Sbjct 104 -----------------EDPSKKIEVAVKQLGKRGLQGHKEWVTEVNFLGVVEHSNLVKL 146
Query 674 HGVCVRGPE----NIMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENK 728
G C E ++V EY+ + ++ L R + ++ +AQ A L+YL +
Sbjct 147 LGHCAEDDERGIQRLLVYEYMPNQSVEFHLSPRSPTVLTWDLRLRIAQDAARGLTYLHEE 206
Query 729 ---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWL 779
++ + NILL + KLSD G+ S + V + +
Sbjct 207 MDFQIIFRDFKSSNILLDE-------NWTAKLSDFGLARLGPSPGSSHVSTDVVGTMGYA 259
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF---------YQRQ 830
APE + G L++ D WG+G + E+ G PL P ++ R+
Sbjct 260 APEYIQTG--RLTSKSDVWGYGVFIYELI-TGRRPLDRNKPKGEQKLLEWVRPYLSDTRR 316
Query 831 HRL----------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880
RL S +LA + + CLT RP +L +T++ +
Sbjct 317 FRLIVDPRLEGKYMIKSVQKLAVVANLCLTRNAKARPKMSEVLEMVTKIVEASSPGNGGK 376
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
P + K + + +G G
Sbjct 377 KPQLVPLKSQETSRVEEGKNKKVLDGAEG 405
>sp|Q9T0J1|CRK26_ARATH Cysteine-rich receptor-like protein kinase
26 OS=Arabidopsis thaliana OX=3702 GN=CRK26 PE=2 SV=1
Length=665
Score = 243 bits (620), Expect = 4e-67, Method: Composition-based stats.
Identities = 72/327 (22%), Positives = 130/327 (40%), Gaps = 19/327 (6%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+ + + ++ + + LGEG FG V G+ +AV
Sbjct 317 ENKHENENISTDSMKFDFSVLQDATSHFSLENKLGEGGFGAVYKGVL-----SDGQKIAV 371
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K L + Q + +K E ++ L H +++K G + E+ LV E++P SL +
Sbjct 372 KRLSKNA-QQGETEFKNEFLLVAKLQHRNLVKLLGYSIEGTER--LLVYEFLPHTSLDKF 428
Query 990 L----PRHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDF 1042
+ + + + G+ YLH IHRDL A N+LLD + KI DF
Sbjct 429 IFDPIQGNELEWEIRYKIIGGVARGLLYLHQDSRLRIIHRDLKASNILLDEEMTPKIADF 488
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSS 1101
G+A+ H R + APE + +F + +DV+SFGV + E+++ +S
Sbjct 489 GMARLFDIDHTTQRYTNRIVGTFGYMAPEYVMHGQFSFKTDVYSFGVLVLEIISGKKNSG 548
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERL--PRPDKCPCEVYHLMKNCWETEASFR 1159
S +LI A L+++ ++ C + + + R
Sbjct 549 FSSEDSMGDLISFAWRNWKEGVALNLVDKILMTMSSYSSNMIMRCINIGLLCVQEKVAER 608
Query 1160 PTFENLIPILK-TVHEKYQGQAPSVFS 1185
P+ +++ +L + P+ FS
Sbjct 609 PSMASVVLMLDGHTIALSEPSKPAFFS 635
Score = 219 bits (558), Expect = 5e-59, Method: Composition-based stats.
Identities = 62/409 (15%), Positives = 119/409 (29%), Gaps = 67/409 (16%)
Query 469 GLYLIHWSTSHPYRLILTVAQRS--QAPDGMQSLRLRKFPIEQQDGAFVLEGWG-RSFPS 525
G Y++ S +L A D + P G ++
Sbjct 227 GSYVMSPSC------MLAYAPWRFYDPVDTDDPSSVPATPSRPPKNETRSVTQGDKNRGV 280
Query 526 VRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVD 585
+ L A + + L + N S +
Sbjct 281 PKALIFASASVAIVVLFIVLLVVFLKLRRKENIRNSENKHENENISTDSMKFDFSVLQDA 340
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ + LG+G VY+G L ++ +K L
Sbjct 341 TSHFSLENKLGEGGFGAVYKGVLSDGQ-------------------------KIAVKRLS 375
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR--ER 703
+ F L++++ H +L + G + G E ++V E++ H LD ++ +
Sbjct 376 KNAQQGETEFKNEFLLVAKLQHRNLVKLLGYSIEGTERLLVYEFLPHTSLDKFIFDPIQG 435
Query 704 GHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ + + +A L YL ++H ++ NILL K++D
Sbjct 436 NELEWEIRYKIIGGVARGLLYLHQDSRLRIIHRDLKASNILLDEEMTP-------KIADF 488
Query 761 GVGL-------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ V ++APE + G S D + FG +LEI +
Sbjct 489 GMARLFDIDHTTQRYTNRIVGTFGYMAPEYVMHG--QFSFKTDVYSFGVLVLEIISGKKN 546
Query 814 --PLQSRSPSEKEHFYQRQH----------RLPEPSCPQLATLTSQCLT 850
S + F R ++ + + +C+
Sbjct 547 SGFSSEDSMGDLISFAWRNWKEGVALNLVDKILMTMSSYSSNMIMRCIN 595
>sp|Q9LDM5|CRK31_ARATH Putative cysteine-rich receptor-like protein
kinase 31 OS=Arabidopsis thaliana OX=3702 GN=CRK31 PE=3
SV=1
Length=666
Score = 243 bits (620), Expect = 4e-67, Method: Composition-based stats.
Identities = 61/326 (19%), Positives = 109/326 (33%), Gaps = 64/326 (20%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
SP++L + V ++ + LGQG VY+G L
Sbjct 320 TSPQSLQF-DFTTIEVATDNFSRNNKLGQGGFGEVYKGML-------------------- 358
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
E + +K L + F +++++ H +L + G C+ E I+V E
Sbjct 359 -----PNETEIAVKRLSSNSGQGTQEFKNEVVIVAKLQHKNLVRLLGFCIERDEQILVYE 413
Query 689 YVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLA 743
+V + LD +L + + W + + + L YL + ++H ++ NILL
Sbjct 414 FVSNKSLDYFLFDPKMKSQLDWKRRYNIIGGVTRGLLYLHQDSRLTIIHRDIKASNILLD 473
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDK 797
K++D G+ + V ++ PE + G ST D
Sbjct 474 -------ADMNPKIADFGMARNFRVDQTEDQTGRVVGTFGYMPPEYVTHG--QFSTKSDV 524
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------------ 839
+ FG +LEI + + + RL P
Sbjct 525 YSFGVLILEIVCGKKNSSFFQMDDSGGNLVTHVWRLWNNDSPLDLIDPAIKESYDNDEVI 584
Query 840 QLATLTSQCLTYEPTQRPSFRTILRD 865
+ + C+ P RP TI +
Sbjct 585 RCIHIGILCVQETPADRPEMSTIFQM 610
Score = 242 bits (618), Expect = 7e-67, Method: Composition-based stats.
Identities = 69/315 (22%), Positives = 119/315 (38%), Gaps = 18/315 (6%)
Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE 925
L+ H D+ + + LG+G FG+V
Sbjct 308 YKTLKYHTDDDMTSPQSLQFDFTTIEVATDNFSRNNKLGQGGFGEVYKGMLPNE-----T 362
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
+AVK L ++ G Q +K E+ I+ L H+++++ G C ++ E+ LV E+V S
Sbjct 363 EIAVKRLSSNSG-QGTQEFKNEVVIVAKLQHKNLVRLLGFCIERDEQ--ILVYEFVSNKS 419
Query 986 LRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVK 1038
L +L + + + + G+ YLH IHRD+ A N+LLD D K
Sbjct 420 LDYFLFDPKMKSQLDWKRRYNIIGGVTRGLLYLHQDSRLTIIHRDIKASNILLDADMNPK 479
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
I DFG+A+ + + PE + +F SDV+SFGV + E++
Sbjct 480 IADFGMARNFRVDQTEDQT-GRVVGTFGYMPPEYVTHGQFSTKSDVYSFGVLILEIVCGK 538
Query 1099 D--SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156
S L+ +L++ + + H+ C +
Sbjct 539 KNSSFFQMDDSGGNLVTHVWRLWNNDSPLDLIDPAIKESYDNDEVIRCIHIGILCVQETP 598
Query 1157 SFRPTFENLIPILKT 1171
+ RP + +L
Sbjct 599 ADRPEMSTIFQMLTN 613
>sp|Q9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 OS=Homo
sapiens OX=9606 GN=STK24 PE=1 SV=1
Length=443
Score = 236 bits (603), Expect = 4e-67, Method: Composition-based stats.
Identities = 68/266 (26%), Positives = 118/266 (44%), Gaps = 24/266 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G FG+V + ++ T ++VA+K + + +QEI +L ++ K
Sbjct 41 KIGKGSFGEV----FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTK 96
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
Y G + L ++MEY+ GS D L + Q+ ++I +G+ YLH++ IH
Sbjct 97 YYGSYLKDTK--LWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIH 154
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RD+ A NVLL VK+ DFG+A + + R FW APE +K+ +
Sbjct 155 RDIKAANVLLSEHGEVKLADFGVAGQLTD---TQIKRNTFVGTPFWMAPEVIKQSAYDSK 211
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
+D+WS G+T EL ++ +++ L+ +
Sbjct 212 ADIWSLGITAIELARGEPP---------------HSELHPMKVLFLIPKNNPPTLEGNYS 256
Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167
+ ++ C E SFRPT + L+
Sbjct 257 KPLKEFVEACLNKEPSFRPTAKELLK 282
Score = 217 bits (553), Expect = 2e-60, Method: Composition-based stats.
Identities = 70/337 (21%), Positives = 126/337 (37%), Gaps = 63/337 (19%)
Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRT 601
+ RR LP PG ++NL +A P L T+L +G+G+
Sbjct 9 GLALNKRRATLPHPGGSTNL------KADPEEL--------------FTKLEKIGKGSFG 48
Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETAS 660
V++G D + V +K++D D + +
Sbjct 49 EVFKGI------------------------DNRTQKVVAIKIIDLEEAEDEIEDIQQEIT 84
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
++SQ ++ +G ++ + ++ EY+ G L E G + + +++
Sbjct 85 VLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL--EPGPLDETQIATILREILK 142
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGALSREERVERI 776
L YL ++ +H ++ N+LL+ G +KL+D GV + R V
Sbjct 143 GLDYLHSEKKIHRDIKAANVLLSEHGE-------VKLADFGVAGQLTDTQIKRNTFVGTP 195
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH--RLP 834
W+APE + A + D W G T +E+ GE P P + + + L
Sbjct 196 FWMAPEVIKQSA--YDSKADIWSLGITAIELA-RGEPPHSELHPMKVLFLIPKNNPPTLE 252
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
L CL EP+ RP+ + +L+ L+
Sbjct 253 GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRN 289
>sp|Q39086|SD17_ARATH Receptor-like serine/threonine-protein kinase
SD1-7 OS=Arabidopsis thaliana OX=3702 GN=SD17 PE=1 SV=1
Length=843
Score = 246 bits (629), Expect = 4e-67, Method: Composition-based stats.
Identities = 74/287 (26%), Positives = 114/287 (40%), Gaps = 21/287 (7%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
LG+G FG V G+ +AVK L Q + E+ ++ L
Sbjct 517 NNFSNDNKLGQGGFGIVYKGRL-----LDGKEIAVKRLSK-MSSQGTDEFMNEVRLIAKL 570
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEG 1010
H ++++ GCC D+GEK L+ EY+ SL +L ++ + I G
Sbjct 571 QHINLVRLLGCCVDKGEK--MLIYEYLENLSLDSHLFDQTRSSNLNWQKRFDIINGIARG 628
Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH IHRDL A NVLLD + KI DFG+A+ R +
Sbjct 629 LLYLHQDSRCRIIHRDLKASNVLLDKNMTPKISDFGMARIFGREETEANTRR-VVGTYGY 687
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTE 1126
+PE + F SDV+SFGV L E+++ + L L+G E
Sbjct 688 MSPEYAMDGIFSMKSDVFSFGVLLLEIISGKRNKGFYNSNRDLNLLGFVWRHWKEGNELE 747
Query 1127 LLERGERLPRPDKCPC----EVYHLMKNCWETEASFRPTFENLIPIL 1169
+++ K P + C + A RP +++ +L
Sbjct 748 IVDPINIDSLSSKFPTHEILRCIQIGLLCVQERAEDRPVMSSVMVML 794
Score = 226 bits (575), Expect = 5e-60, Method: Composition-based stats.
Identities = 51/253 (20%), Positives = 87/253 (34%), Gaps = 45/253 (18%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ + LGQG VY+GRL + +K L
Sbjct 515 ATNNFSNDNKLGQGGFGIVYKGRLLDGK-------------------------EIAVKRL 549
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
F L++++ H +L + G CV E +++ EY+E+ LD L +
Sbjct 550 SKMSSQGTDEFMNEVRLIAKLQHINLVRLLGCCVDKGEKMLIYEYLENLSLDSHLFDQTR 609
Query 705 HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ W + + +A L YL ++H ++ N+LL + + K+SD
Sbjct 610 SSNLNWQKRFDIINGIARGLLYLHQDSRCRIIHRDLKASNVLLDK-------NMTPKISD 662
Query 760 PGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ + V +++PE G S D + FG LLEI
Sbjct 663 FGMARIFGREETEANTRRVVGTYGYMSPEYAMDGI--FSMKSDVFSFGVLLLEIISGKRN 720
Query 814 PLQSRSPSEKEHF 826
S +
Sbjct 721 KGFYNSNRDLNLL 733
>sp|P18160|SPLA_DICDI Dual specificity protein kinase splA OS=Dictyostelium
discoideum OX=44689 GN=splA PE=1 SV=3
Length=2410
Score = 253 bits (645), Expect = 4e-67, Method: Composition-based stats.
Identities = 85/297 (29%), Positives = 131/297 (44%), Gaps = 46/297 (15%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEH 958
+ +G+G FG+V + T+ VA+K + D ++ E+ IL L H +
Sbjct 2119 QTIGKGFFGEVKRGYWRETD------VAIKIIYRDQFKTKSSLVMFQNEVGILSKLRHPN 2172
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ----LLLFAQQICEGMAYL 1014
++++ G C GE +V E++ GSLR +L H L Q L A I +GM YL
Sbjct 2173 VVQFLGACTAGGEDHHCIVTEWMGGGSLRQFLTDHFNLLEQNPHIRLKLALDIAKGMNYL 2232
Query 1015 H--AQHYIHRDLAARNVLLDN-------------DRLVKIGDFGLAKAVPEGHEYYRVRE 1059
H +HRDL++RN+LLD+ D KI DFGL++ + +
Sbjct 2233 HGWTPPILHRDLSSRNILLDHNIDPKNPVVSSRQDIKCKISDFGLSR-LKMEQASQMTQS 2291
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQ 1118
G P + APE K SDV+S+G+ L+ELLT + Q P K L
Sbjct 2292 VGCIP--YMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAY---- 2345
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
R P P + ++ CW++ RPTF+ +I LK + ++
Sbjct 2346 -----------ESYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQIIVHLKEMEDQ 2391
Score = 227 bits (579), Expect = 5e-59, Method: Composition-based stats.
Identities = 65/315 (21%), Positives = 121/315 (38%), Gaps = 51/315 (16%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
S + +D E+ +G+G V G R E V
Sbjct 2106 SEYEIDFNELEFGQTIGKGFFGEVKRGYWR--------------------------ETDV 2139
Query 640 VLKVLDPSHHDIALA---FYETASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEHGP 694
+K++ + F ++S++ H ++ G C G E + +VTE++ G
Sbjct 2140 AIKIIYRDQFKTKSSLVMFQNEVGILSKLRHPNVVQFLGACTAGGEDHHCIVTEWMGGGS 2199
Query 695 LDVWLRRERGHVPMA--WKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLAEG 750
L +L + ++ +A +A ++YL ++H ++ RNILL +
Sbjct 2200 LRQFLTDHFNLLEQNPHIRLKLALDIAKGMNYLHGWTPPILHRDLSSRNILLDHNIDPKN 2259
Query 751 ------TSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGF 800
K+SD G+ + + + V IP++APE G +N S D + +
Sbjct 2260 PVVSSRQDIKCKISDFGLSRLKMEQASQMTQSVGCIPYMAPEVFKGDSN--SEKSDVYSY 2317
Query 801 GATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857
G L E+ E P Q P + H + + +P + + + +QC P RP
Sbjct 2318 GMVLFELLTSDE-PQQDMKPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDSNPDSRP 2376
Query 858 SFRTILRDLTRLQPH 872
+F+ I+ L ++
Sbjct 2377 TFKQIIVHLKEMEDQ 2391
>sp|H2L099|GCK1_CAEEL Germinal center kinase 1 OS=Caenorhabditis
elegans OX=6239 GN=gck-1 PE=1 SV=1
Length=653
Score = 242 bits (618), Expect = 5e-67, Method: Composition-based stats.
Identities = 70/271 (26%), Positives = 119/271 (44%), Gaps = 23/271 (8%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
K +G G FG+V Y ++ TG +VA+K + + +QEI +L
Sbjct 34 FTKQERIGRGSFGEV----YKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDS 89
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016
+++ KY G + L ++MEY+ GS D + + + + ++I +G+ YLH+
Sbjct 90 QYVTKYFGSFLKGSK--LWIIMEYLGGGSALDLTKSGKLDESHIAVILREILKGLEYLHS 147
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ IHRD+ A NVL+ VK+ DFG+A + E + R FW APE +K+
Sbjct 148 ERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTE---TVKKRITFVGSPFWMAPELIKQS 204
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+ Y +D+WS G+T EL + S L I + VL+ ++
Sbjct 205 SYDYKADIWSLGITAIELANG-EPPHSDLHPMRVLFLIPKNPPPVLQGSQ---------- 253
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
++ C + RP+ L+
Sbjct 254 ---WSKPFKEFVEMCLNKDPENRPSASTLLK 281
Score = 201 bits (512), Expect = 4e-53, Method: Composition-based stats.
Identities = 57/311 (18%), Positives = 110/311 (35%), Gaps = 50/311 (16%)
Query 571 PRTLNLSQLSFHRVDQKE------ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
PR + + + R+ ++ T+ +G+G+ VY+G
Sbjct 10 PRQADDDSMKWDRIYIQKLDPEVIFTKQERIGRGSFGEVYKGI----------------- 52
Query 625 DPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
D V +K++D D + ++SQ ++ G ++G +
Sbjct 53 -------DNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSKL 105
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
++ EY+ G + G + + V+ +++ L YL ++ +H ++ N+L++
Sbjct 106 WIIMEYLGGGSALDL--TKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVS 163
Query 744 RLGLAEGTSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
G +K++D GV R V W+APE + + D W
Sbjct 164 EHGD-------VKVADFGVAGQLTETVKKRITFVGSPFWMAPELIKQSSYDY--KADIWS 214
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP---EPSCPQLATLTSQCLTYEPTQR 856
G T +E+ +GE P P + CL +P R
Sbjct 215 LGITAIELA-NGEPPHSDLHPMRVLFLIPKNPPPVLQGSQWSKPFKEFVEMCLNKDPENR 273
Query 857 PSFRTILRDLT 867
PS T+L+
Sbjct 274 PSASTLLKHQF 284
>sp|Q9SN43|CIPKC_ARATH CBL-interacting serine/threonine-protein
kinase 12 OS=Arabidopsis thaliana OX=3702 GN=CIPK12 PE=1 SV=1
Length=489
Score = 238 bits (606), Expect = 5e-67, Method: Composition-based stats.
Identities = 69/268 (26%), Positives = 112/268 (42%), Gaps = 26/268 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960
LG G F KV L N T E VA+K + + + + K+EI ILR + H +I+
Sbjct 32 LGHGTFAKVYL----ARNVKTNESVAIKVIDKEKVLKGGLIAHIKREISILRRVRHPNIV 87
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ + + + VMEYV G L + + + + + QQ+ + + HA+
Sbjct 88 QLFEVMATKAK--IYFVMEYVRGGELFNKVAKGRLKEEVARKYFQQLISAVTFCHARGVY 145
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
HRDL N+LLD + +K+ DFGL+ + + +P + APE L +
Sbjct 146 HRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPA-YVAPEVLARKGYDA 204
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
D+WS GV L+ L+ V+ + + + RGE P
Sbjct 205 AKVDIWSCGVILFVLMAGYLPFHD---------------RNVMAMYKKIYRGE-FRCPRW 248
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
E+ L+ ET R TF ++
Sbjct 249 FSTELTRLLSKLLETNPEKRFTFPEIME 276
Score = 184 bits (466), Expect = 2e-48, Method: Composition-based stats.
Identities = 58/307 (19%), Positives = 97/307 (32%), Gaps = 45/307 (15%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH- 648
LG GT VY R+ V +KV+D
Sbjct 27 EMGKLLGHGTFAKVYLA------------------------RNVKTNESVAIKVIDKEKV 62
Query 649 --HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
+ S++ +V H ++ + V + V EYV G L + +G +
Sbjct 63 LKGGLIAHIKREISILRRVRHPNIVQLFEVMATKAKIYFVMEYVRGGELFN--KVAKGRL 120
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--- 763
QQL SA+++ + + H ++ N+LL G +K+SD G+
Sbjct 121 KEEVARKYFQQLISAVTFCHARGVYHRDLKPENLLLDENG-------NLKVSDFGLSAVS 173
Query 764 ---LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
++APE L + +D W G L + G P R+
Sbjct 174 DQIRQDGLFHTFCGTPAYVAPEVLARKGYD-AAKVDIWSCGVIL-FVLMAGYLPFHDRNV 231
Query 821 SEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
R R P +L L S+ L P +R +F I+ + +
Sbjct 232 MAMYKKIYRGEFRCPRWFSTELTRLLSKLLETNPEKRFTFPEIMENSWFKKGFKHIKFYV 291
Query 880 VNPDSPA 886
+
Sbjct 292 EDDKLCN 298
>sp|Q99KH8|STK24_MOUSE Serine/threonine-protein kinase 24 OS=Mus
musculus OX=10090 GN=Stk24 PE=1 SV=1
Length=431
Score = 236 bits (601), Expect = 5e-67, Method: Composition-based stats.
Identities = 70/266 (26%), Positives = 121/266 (45%), Gaps = 24/266 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G FG+V + ++ T ++VA+K + + +QEI +L ++ K
Sbjct 29 KIGKGSFGEV----FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTK 84
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
Y G + L ++MEY+ GS D L + Q+ ++I +G+ YLH++ IH
Sbjct 85 YYGSYLKDTK--LWIIMEYLGGGSALDLLEPGPLDEIQIATILREILKGLDYLHSEKKIH 142
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RD+ A NVLL VK+ DFG+A + + R FW APE +K+ +
Sbjct 143 RDIKAANVLLSEHGEVKLADFGVAGQLTD---TQIKRNTFVGTPFWMAPEVIKQSAYDSK 199
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
+D+WS G+T EL + PP ++ +++ L+ +
Sbjct 200 ADIWSLGITAIEL-----AKGEPP----------HSELHPMKVLFLIPKNNPPTLEGNYS 244
Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167
+ ++ C E SFRPT + L+
Sbjct 245 KPLKEFVEACLNKEPSFRPTAKELLK 270
Score = 213 bits (542), Expect = 5e-59, Method: Composition-based stats.
Identities = 63/310 (20%), Positives = 119/310 (38%), Gaps = 44/310 (14%)
Query 570 SPRTLNLSQLSFHRVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
SP L + + D +E T+L +G+G+ V++G
Sbjct 4 SPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGI--------------------- 42
Query 629 PGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
D + V +K++D D + +++SQ ++ +G ++ + ++
Sbjct 43 ---DNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIM 99
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
EY+ G L E G + + +++ L YL ++ +H ++ N+LL+ G
Sbjct 100 EYLGGGSALDLL--EPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE 157
Query 748 AEGTSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+KL+D GV + R V W+APE + A + D W G T
Sbjct 158 -------VKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSA--YDSKADIWSLGIT 208
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861
+E+ GE P P + + + L L CL EP+ RP+ +
Sbjct 209 AIELA-KGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKE 267
Query 862 ILRDLTRLQP 871
+L+ ++
Sbjct 268 LLKHKFIIRN 277
>sp|Q9LDS6|CRK32_ARATH Putative cysteine-rich receptor-like protein
kinase 32 OS=Arabidopsis thaliana OX=3702 GN=CRK32 PE=3
SV=1
Length=656
Score = 242 bits (618), Expect = 6e-67, Method: Composition-based stats.
Identities = 74/329 (22%), Positives = 120/329 (36%), Gaps = 26/329 (8%)
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919
R + L+P D+ + + LG+G FG+V
Sbjct 284 RKRRQSYKTLKPKTDDDMTSPQSLQFDFMTLEAATDKFSRNNKLGKGGFGEVYKGMLPNE 343
Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979
VAVK L ++ G Q +K E+ I+ L H+++++ G C ++ E+ LV E
Sbjct 344 -----TEVAVKRLSSNSG-QGTQEFKNEVVIVAKLQHKNLVRLLGFCLERDEQ--ILVYE 395
Query 980 YVPLGSLRDYL------------PRHSIGLAQLLLFAQQICEGMAYLHAQH---YIHRDL 1024
+VP SL +L + + + I G+ YLH IHRD+
Sbjct 396 FVPNKSLNYFLFGNKQKHLLDPTKKSQLDWKRRYNIIGGITRGLLYLHQDSRLTIIHRDI 455
Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084
A N+LLD D KI DFG+A+ R + PE + +F SDV
Sbjct 456 KASNILLDADMNPKIADFGMARNFRVDQTEDNTRR-VVGTFGYMPPEYVTHGQFSTKSDV 514
Query 1085 WSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
+SFGV + E++ S L+ +L++ +
Sbjct 515 YSFGVLILEIVCGKKNSSFYKIDDSGGNLVTHVWRLWNNDSPLDLIDPAIEESCDNDKVI 574
Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKT 1171
H+ C + RP + +L
Sbjct 575 RCIHIGLLCVQETPVDRPEMSTIFQMLTN 603
Score = 236 bits (603), Expect = 5e-65, Method: Composition-based stats.
Identities = 58/334 (17%), Positives = 107/334 (32%), Gaps = 72/334 (22%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
SP++L + ++ + LG+G VY+G L
Sbjct 302 TSPQSLQF-DFMTLEAATDKFSRNNKLGKGGFGEVYKGML-------------------- 340
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
E V +K L + F +++++ H +L + G C+ E I+V E
Sbjct 341 -----PNETEVAVKRLSSNSGQGTQEFKNEVVIVAKLQHKNLVRLLGFCLERDEQILVYE 395
Query 689 YVEHGPLDVWLRRE----------RGHVPMAWKMVVAQQLASALSYLENKN---LVHGNV 735
+V + L+ +L + + + + + L YL + ++H ++
Sbjct 396 FVPNKSLNYFLFGNKQKHLLDPTKKSQLDWKRRYNIIGGITRGLLYLHQDSRLTIIHRDI 455
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGAN 789
NILL K++D G+ + V ++ PE + G
Sbjct 456 KASNILLD-------ADMNPKIADFGMARNFRVDQTEDNTRRVVGTFGYMPPEYVTHG-- 506
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP---------- 839
ST D + FG +LEI + + + RL P
Sbjct 507 QFSTKSDVYSFGVLILEIVCGKKNSSFYKIDDSGGNLVTHVWRLWNNDSPLDLIDPAIEE 566
Query 840 --------QLATLTSQCLTYEPTQRPSFRTILRD 865
+ + C+ P RP TI +
Sbjct 567 SCDNDKVIRCIHIGLLCVQETPVDRPEMSTIFQM 600
>sp|Q8R4K2|IRAK4_MOUSE Interleukin-1 receptor-associated kinase
4 OS=Mus musculus OX=10090 GN=Irak4 PE=1 SV=1
Length=459
Score = 236 bits (603), Expect = 6e-67, Method: Composition-based stats.
Identities = 82/357 (23%), Positives = 133/357 (37%), Gaps = 28/357 (8%)
Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR----------LQPHNLADVLTVNP 882
LP +A C + T + ++ +
Sbjct 112 LPPREAATVAQTHGPCQEKDRTSVMPMPKLEHSCEPPDSSSPDNRSVESSDTRFHSFSFH 171
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD---CGPQ 939
+ + + +GEG FG V C + T +VAVK L A +
Sbjct 172 ELKSITNNFDEQPASAGGNRMGEGGFGVVYKGCVNNT------IVAVKKLGAMVEISTEE 225
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSI 995
+ + QEI ++ T HE++++ G D +L LV Y+P GSL D L +
Sbjct 226 LKQQFDQEIKVMATCQHENLVELLGFSSDSD--NLCLVYAYMPNGSLLDRLSCLDGTPPL 283
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
AQ G+ +LH H+IHRD+ + N+LLD D KI DFGLA+A +
Sbjct 284 SWHTRCKVAQGTANGIRFLHENHHIHRDIKSANILLDKDFTAKISDFGLARASARLAQTV 343
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
+ + APE L+ SD++SFGV L EL+T + L L
Sbjct 344 MTSRIVGTTA-YMAPEALRGE-ITPKSDIYSFGVVLLELITGLAAVDENREPQLLLDIKE 401
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ + + + + P +Y C + + RP + +L+ +
Sbjct 402 EIEDEEKTIEDYTDEKMSDADPASV-EAMYSAASQCLHEKKNRRPDIAKVQQLLQEM 457
Score = 206 bits (525), Expect = 2e-56, Method: Composition-based stats.
Identities = 82/459 (18%), Positives = 145/459 (32%), Gaps = 110/459 (24%)
Query 485 LTVAQRSQAPDG-MQSLRLRKFPIEQQDGAF----VLEGWGRSFPSVRELGAALQGCLL- 538
L VA + + D +R+F Q G +L WG + +V +L L L
Sbjct 35 LAVAIKKPSGDDRYNQFHIRRFEALLQTGKSPTCELLFDWGTTNCTVGDLVDLLVQIELF 94
Query 539 --------------------RAGDDCFSLRRCC--------LPQPGETSNLIIMRGARAS 570
R C +P P + +
Sbjct 95 APATLLLPDAVPQTVKSLPPREAATVAQTHGPCQEKDRTSVMPMPKLEHSCEPPDSSSPD 154
Query 571 PRTLNLSQLSFHRVDQKEITQL-------------SHLGQGTRTNVYEGRLRVEGSGDPE 617
R++ S FH E+ + + +G+G VY+G +
Sbjct 155 NRSVESSDTRFHSFSFHELKSITNNFDEQPASAGGNRMGEGGFGVVYKGCV--------- 205
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDP----SHHDIALAFYETASLMSQVSHTHLAFV 673
V +K L S ++ F + +M+ H +L +
Sbjct 206 -----------------NNTIVAVKKLGAMVEISTEELKQQFDQEIKVMATCQHENLVEL 248
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLV 731
G +V Y+ +G L L G P++W + VAQ A+ + +L + +
Sbjct 249 LGFSSDSDNLCLVYAYMPNGSLLDRLSCLDGTPPLSWHTRCKVAQGTANGIRFLHENHHI 308
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA------LSREERVERIPWLAPECLP 785
H ++ NILL + K+SD G+ + + V ++APE L
Sbjct 309 HRDIKSANILLDK-------DFTAKISDFGLARASARLAQTVMTSRIVGTTAYMAPEALR 361
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ----- 840
G ++ D + FG LLE+ A ++R P + +
Sbjct 362 G---EITPKSDIYSFGVVLLELITGLAAVDENREPQLLLDIKEEIEDEEKTIEDYTDEKM 418
Query 841 ----------LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + SQCL + +RP + + L +
Sbjct 419 SDADPASVEAMYSAASQCLHEKKNRRPDIAKVQQLLQEM 457
>sp|Q54IP4|SHKB_DICDI Dual specificity protein kinase shkB OS=Dictyostelium
discoideum OX=44689 GN=shkB PE=3 SV=1
Length=653
Score = 242 bits (618), Expect = 6e-67, Method: Composition-based stats.
Identities = 74/284 (26%), Positives = 129/284 (45%), Gaps = 30/284 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH-RSGWKQEIDILRTLY 955
+ LG G FG V G+ VA+K L ++ + +K+E+ ++ L
Sbjct 174 YNREAKLGSGAFGSVYKGIVR------GKEVAIKKLTQTVFEENTMNEFKKEVSLMAKLR 227
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEG 1010
+ H++ + G C + L +V E +P GS+ L I + +L A+ G
Sbjct 228 NPHLLLFMGACT--APEDLSIVTELMPKGSVHSLLRAKEDTSDFITFKRAILIARDTVLG 285
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
M +LHA + +H DL N+L+D + +VK+ DFGL+K + + + + G + AP
Sbjct 286 MTWLHASNILHLDLKPANLLVDQNWVVKVADFGLSKYMKPDSKDKLLGQAG--SPLYMAP 343
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E L + DV+SF + L+ELLT + + + +L + ++ +
Sbjct 344 EMLVNQPYDGKVDVFSFSILLWELLTKQEPYNKLYSSYPQL------------VEGVVNK 391
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP--ILKTV 1172
R PD P + L+ CW+ S RP+F + IL+T+
Sbjct 392 KNRPIIPDYFPTRLKDLLARCWDHYPSRRPSFAEISKQRILETI 435
Score = 211 bits (537), Expect = 3e-56, Method: Composition-based stats.
Identities = 64/331 (19%), Positives = 128/331 (39%), Gaps = 61/331 (18%)
Query 562 IIMRGARASPRTLNLSQLSF----------HRVDQKEITQLS--HLGQGTRTNVYEGRLR 609
+I+ G+ T +S S +D+ EI+ LG G +VY+G +R
Sbjct 135 VILNGSLTEDSTSTISPDSTKNRDEEEIIRWEIDRNEISYNREAKLGSGAFGSVYKGIVR 194
Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSH 667
+ V +K L + + F + SLM+++ +
Sbjct 195 GK--------------------------EVAIKKLTQTVFEENTMNEFKKEVSLMAKLRN 228
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH---VPMAWKMVVAQQLASALSY 724
HL G C + +VTE + G + LR + + +++A+ +++
Sbjct 229 PHLLLFMGACTAPEDLSIVTELMPKGSVHSLLRAKEDTSDFITFKRAILIARDTVLGMTW 288
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIPWL 779
L N++H ++ N+L+ + + +K++D G+ + + ++
Sbjct 289 LHASNILHLDLKPANLLVDQ-------NWVVKVADFGLSKYMKPDSKDKLLGQAGSPLYM 341
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS--PSEKEHFYQRQHR--LPE 835
APE L +D + F L E+ E + S P E +++R +P+
Sbjct 342 APEMLVN--QPYDGKVDVFSFSILLWELLTKQEPYNKLYSSYPQLVEGVVNKKNRPIIPD 399
Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
+L L ++C + P++RPSF I +
Sbjct 400 YFPTRLKDLLARCWDHYPSRRPSFAEISKQR 430
>sp|Q8RZV7|MSP1_ORYSJ Leucine-rich repeat receptor protein kinase
MSP1 OS=Oryza sativa subsp. japonica OX=39947 GN=MSP1 PE=1
SV=1
Length=1294
Score = 251 bits (641), Expect = 6e-67, Method: Composition-based stats.
Identities = 77/298 (26%), Positives = 121/298 (41%), Gaps = 25/298 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G+G FG V G VA+K L Q + E++ + + H +++
Sbjct 1006 HIIGDGGFGTVYKAALPE-----GRRVAIKRLHGGHQFQGDREFLAEMETIGKVKHPNLV 1060
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLH 1015
G C E+ L+ EY+ GSL +L + +G L G+A+LH
Sbjct 1061 PLLGYCVCGDER--FLIYEYMENGSLEMWLRNRADALEALGWPDRLKICLGSARGLAFLH 1118
Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
H IHRD+ + N+LLD + ++ DFGLA+ + + V D + PE
Sbjct 1119 HGFVPHIIHRDMKSSNILLDENFEPRVSDFGLARIISACETH--VSTDIAGTFGYIPPEY 1176
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
K DV+SFGV + ELLT Q L+G + + + EL +
Sbjct 1177 GLTMKSTTKGDVYSFGVVMLELLTGRPPTGQEEVQGGGNLVGWVRWMIARGKQNELFDPC 1236
Query 1132 ERLPRPDKCPCEVYH---LMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
LP ++ + ++C E RPT ++ LK H G P V +V
Sbjct 1237 --LPVSSVWREQMARVLAIARDCTADEPFKRPTMLEVVKGLKMTHGMECG--PLVVTV 1290
Score = 218 bits (556), Expect = 1e-56, Method: Composition-based stats.
Identities = 71/390 (18%), Positives = 132/390 (34%), Gaps = 75/390 (19%)
Query 525 SVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV 584
+ L L+ L+R+ F TS ++ P ++NL+ +
Sbjct 929 VLVLLAVYLRRKLVRSRPLAFESASKAKATVEPTSTDELLGKKSREPLSINLATFEHALL 988
Query 585 ---------DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
+ +++ +G G VY+ L
Sbjct 989 RVTADDILKATENFSKVHIIGDGGFGTVYKAALPEGR----------------------- 1025
Query 636 ELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
RV +K L H F + +V H +L + G CV G E ++ EY+E+G
Sbjct 1026 --RVAIKRLHGGHQFQGDREFLAEMETIGKVKHPNLVPLLGYCVCGDERFLIYEYMENGS 1083
Query 695 LDVWLRRERGHVP---MAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLA 748
L++WLR + ++ + A L++L + +++H ++ NILL
Sbjct 1084 LEMWLRNRADALEALGWPDRLKICLGSARGLAFLHHGFVPHIIHRDMKSSNILLDE---- 1139
Query 749 EGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+ ++SD G+ + E V ++ PE G +T D + FG
Sbjct 1140 ---NFEPRVSDFGLARIISACETHVSTDIAGTFGYIPPEY--GLTMKSTTKGDVYSFGVV 1194
Query 804 LLEICFDGEAPLQSRSPS---------EKEHFYQRQHRLPEPSCP----------QLATL 844
+LE+ G P +Q+ L +P P ++ +
Sbjct 1195 MLELL-TGRPPTGQEEVQGGGNLVGWVRWMIARGKQNELFDPCLPVSSVWREQMARVLAI 1253
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
C EP +RP+ +++ L
Sbjct 1254 ARDCTADEPFKRPTMLEVVKGLKMTHGMEC 1283
>sp|Q9FN92|Y5597_ARATH Probable receptor-like protein kinase At5g59700
OS=Arabidopsis thaliana OX=3702 GN=At5g59700 PE=1 SV=1
Length=829
Score = 246 bits (627), Expect = 6e-67, Method: Composition-based stats.
Identities = 76/292 (26%), Positives = 126/292 (43%), Gaps = 23/292 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FGKV G VAVK Q + ++ EI++L H H++
Sbjct 488 IGVGGFGKVYKGEL-----HDGTKVAVKRANPK-SQQGLAEFRTEIEMLSQFRHRHLVSL 541
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHA--- 1016
G C++ E + LV EY+ G+L+ +L S+ Q L G+ YLH
Sbjct 542 IGYCDENNE--MILVYEYMENGTLKSHLYGSGLLSLSWKQRLEICIGSARGLHYLHTGDA 599
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ IHRD+ + N+LLD + + K+ DFGL+K PE + + V + PE +
Sbjct 600 KPVIHRDVKSANILLDENLMAKVADFGLSKTGPEIDQTH-VSTAVKGSFGYLDPEYFRRQ 658
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR---LTELLERGER 1133
+ SDV+SFGV ++E+L C PT E++ +A+ M + L +++ R
Sbjct 659 QLTEKSDVYSFGVVMFEVL--CARPVIDPTLTREMVNLAEWAMKWQKKGQLEHIIDPSLR 716
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK---TVHEKYQGQAPS 1182
+ + C RP+ +++ L+ + E P
Sbjct 717 GKIRPDSLRKFGETGEKCLADYGVDRPSMGDVLWNLEYALQLQEAVVDGDPE 768
Score = 219 bits (558), Expect = 6e-58, Method: Composition-based stats.
Identities = 57/273 (21%), Positives = 94/273 (34%), Gaps = 51/273 (19%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ +G G VY+G L +V +K
Sbjct 478 ATNSFDENRAIGVGGFGKVYKGELHDG-------------------------TKVAVKRA 512
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+P F ++SQ H HL + G C E I+V EY+E+G L L G
Sbjct 513 NPKSQQGLAEFRTEIEMLSQFRHRHLVSLIGYCDENNEMILVYEYMENGTLKSHLYGS-G 571
Query 705 HVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ ++W ++ + A L YL K ++H +V NILL + K++D
Sbjct 572 LLSLSWKQRLEICIGSARGLHYLHTGDAKPVIHRDVKSANILLDE-------NLMAKVAD 624
Query 760 PGVGL-GALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ G + V +L PE L+ D + FG + E+
Sbjct 625 FGLSKTGPEIDQTHVSTAVKGSFGYLDPEYFR--RQQLTEKSDVYSFGVVMFEVLCARPV 682
Query 814 PLQSRSPS-----EKEHFYQRQHRLPEPSCPQL 841
+ + E +Q++ +L P L
Sbjct 683 IDPTLTREMVNLAEWAMKWQKKGQLEHIIDPSL 715
>sp|O81833|SD11_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase SD1-1 OS=Arabidopsis thaliana OX=3702
GN=SD11 PE=1 SV=1
Length=815
Score = 246 bits (627), Expect = 6e-67, Method: Composition-based stats.
Identities = 79/324 (24%), Positives = 126/324 (39%), Gaps = 22/324 (7%)
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916
+ I++ + ++ + LG G FG V
Sbjct 460 CFRKKIMKRYRGENFRKGIEEEDLDLPIFDRKTISIATDDFSYVNFLGRGGFGPVYKGKL 519
Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976
+ G+ +AVK L A+ G Q +K E+ ++ L H ++++ GCC E L
Sbjct 520 E-----DGQEIAVKRLSANSG-QGVEEFKNEVKLIAKLQHRNLVRLLGCCIQGEEC--ML 571
Query 977 VMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNV 1029
+ EY+P SL ++ + + + + G+ YLH IHRDL A NV
Sbjct 572 IYEYMPNKSLDFFIFDERRSTELDWKKRMNIINGVARGILYLHQDSRLRIIHRDLKAGNV 631
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
LLDND KI DFGLAK+ G + + PE + F SDV+SFGV
Sbjct 632 LLDNDMNPKISDFGLAKSFG-GDQSESSTNRVVGTYGYMPPEYAIDGHFSVKSDVFSFGV 690
Query 1090 TLYELLTHCDSSQSPP-TKFLELIGIAQGQMTVLRLTELLERGERLP---RPDKCPCEVY 1145
+ E++T + L L+G R E+ E P+
Sbjct 691 LVLEIITGKTNRGFRHADHDLNLLGHVWKMWVEDREIEVPEEEWLEETSVIPE--VLRCI 748
Query 1146 HLMKNCWETEASFRPTFENLIPIL 1169
H+ C + + RPT +++ +
Sbjct 749 HVALLCVQQKPEDRPTMASVVLMF 772
Score = 236 bits (602), Expect = 1e-63, Method: Composition-based stats.
Identities = 58/371 (16%), Positives = 119/371 (32%), Gaps = 65/371 (18%)
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
+G L + + + + ++ LG+G VY+G+L
Sbjct 476 KGIEEEDLDLPIFDRKTISIATDDFSYVNFLGRGGFGPVYKGKLEDGQ------------ 523
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+ +K L + F L++++ H +L + G C++G E +
Sbjct 524 -------------EIAVKRLSANSGQGVEEFKNEVKLIAKLQHRNLVRLLGCCIQGEECM 570
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRN 739
++ EY+ + LD ++ ER + W +M + +A + YL ++H ++ N
Sbjct 571 LIYEYMPNKSLDFFIFDERRSTELDWKKRMNIINGVARGILYLHQDSRLRIIHRDLKAGN 630
Query 740 ILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLST 793
+LL K+SD G+ S V ++ PE G S
Sbjct 631 VLLDN-------DMNPKISDFGLAKSFGGDQSESSTNRVVGTYGYMPPEYAIDG--HFSV 681
Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS---------------- 837
D + FG +LEI G+ R + ++
Sbjct 682 KSDVFSFGVLVLEII-TGKTNRGFRHADHDLNLLGHVWKMWVEDREIEVPEEEWLEETSV 740
Query 838 CPQLAT---LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894
P++ + C+ +P RP+ +++ + D +
Sbjct 741 IPEVLRCIHVALLCVQQKPEDRPTMASVVLMFGSDSSLPHPTQPGFFTNRNVPDISSSLS 800
Query 895 RYLKKIRDLGE 905
+ +
Sbjct 801 LRSQNEVSITM 811
>sp|Q54TH6|Y9863_DICDI Probable serine/threonine-protein kinase
DDB_G0281745 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0281745
PE=3 SV=1
Length=597
Score = 241 bits (614), Expect = 6e-67, Method: Composition-based stats.
Identities = 70/297 (24%), Positives = 125/297 (42%), Gaps = 32/297 (11%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
+ +K ++G G +G VSL + G VA+K L + + ++E
Sbjct 325 MWNIDYKELKFVGNEIGSGKYGSVSLGYWL------GTPVAIKKL-HENNEETEILVQRE 377
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQ 1005
+ IL+ + H I+++ G ++ ++ + ++ E++ G L D L + + L +
Sbjct 378 LQILKEIRHPQIVQFLGVSRNEKDE-IHIITEFMDGGDLFDALIFGDIPLTWKEKLRISL 436
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
I + +LHA+ +HRDL ++N+LL +R K+ D GLA+ E R
Sbjct 437 DIAQSCRFLHARGILHRDLKSQNILLSTNRRAKLCDLGLARMF---EERINKRYTCVGTE 493
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
W APE + + A DV+SFG+ L E++T + P + A +
Sbjct 494 IWMAPEVCLDQSYSTAVDVFSFGIVLVEIITEKIPDERFPQHRFQFDAPAFLKKV----- 548
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182
P +CP + L +C + RP+F I +L T+ Y
Sbjct 549 -----------PKECPPDFSKLCVDCTKYNPKERPSF---IKVLDTIQNIYDSLPDD 591
Score = 204 bits (520), Expect = 1e-54, Method: Composition-based stats.
Identities = 61/318 (19%), Positives = 115/318 (36%), Gaps = 41/318 (13%)
Query 559 SNLIIMRGARASPRTLNLSQLSFHRVDQKEITQ-LSHLGQGTRTNVYEGRLRVEGSGDPE 617
S+L+ + +D KE+ + +G G +V G
Sbjct 303 SSLVEKSPRNNESTATTATTKDMWNIDYKELKFVGNEIGSGKYGSVSLGYWLG------- 355
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
V +K L ++ + + ++ ++ H + GV
Sbjct 356 -------------------TPVAIKKLHENNEETEILVQRELQILKEIRHPQIVQFLGVS 396
Query 678 V-RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736
E ++TE+++ G L L + K+ ++ +A + +L + ++H ++
Sbjct 397 RNEKDEIHIITEFMDGGDLFDALIFGDIPLTWKEKLRISLDIAQSCRFLHARGILHRDLK 456
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLS 792
+NILL+ T+ KL D G+ R V W+APE S S
Sbjct 457 SQNILLS-------TNRRAKLCDLGLARMFEERINKRYTCVGTEIWMAPEVCLD--QSYS 507
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYE 852
TA+D + FG L+EI + + + ++P+ P + L C Y
Sbjct 508 TAVDVFSFGIVLVEIITEKIPDERFPQHRFQFDAPAFLKKVPKECPPDFSKLCVDCTKYN 567
Query 853 PTQRPSFRTILRDLTRLQ 870
P +RPSF +L + +
Sbjct 568 PKERPSFIKVLDTIQNIY 585
>sp|Q9LX66|HERK_ARATH Receptor-like protein kinase HERK 1 OS=Arabidopsis
thaliana OX=3702 GN=HERK1 PE=1 SV=1
Length=830
Score = 246 bits (627), Expect = 7e-67, Method: Composition-based stats.
Identities = 77/304 (25%), Positives = 133/304 (44%), Gaps = 23/304 (8%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+ R++G G FGKV G VAVK Q + ++ EI++L
Sbjct 483 NNFDESRNIGVGGFGKVYKGEL-----NDGTKVAVKRGNPK-SQQGLAEFRTEIEMLSQF 536
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGM 1011
H H++ G C++ E + L+ EY+ G+++ +L S+ Q L G+
Sbjct 537 RHRHLVSLIGYCDENNE--MILIYEYMENGTVKSHLYGSGLPSLTWKQRLEICIGAARGL 594
Query 1012 AYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
YLH ++ IHRD+ + N+LLD + + K+ DFGL+K PE + + V +
Sbjct 595 HYLHTGDSKPVIHRDVKSANILLDENFMAKVADFGLSKTGPELDQTH-VSTAVKGSFGYL 653
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR---LT 1125
PE + + SDV+SFGV L+E+L C PT E++ +A+ M + L
Sbjct 654 DPEYFRRQQLTDKSDVYSFGVVLFEVL--CARPVIDPTLPREMVNLAEWAMKWQKKGQLD 711
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK---TVHEKYQGQAPS 1182
+++++ R + + C RP+ +++ L+ + E P
Sbjct 712 QIIDQSLRGNIRPDSLRKFAETGEKCLADYGVDRPSMGDVLWNLEYALQLQEAVIDGEPE 771
Query 1183 VFSV 1186
S
Sbjct 772 DNST 775
Score = 220 bits (561), Expect = 3e-58, Method: Composition-based stats.
Identities = 54/272 (20%), Positives = 94/272 (35%), Gaps = 49/272 (18%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ ++G G VY+G L +V +K
Sbjct 481 ATNNFDESRNIGVGGFGKVYKGELNDG-------------------------TKVAVKRG 515
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER- 703
+P F ++SQ H HL + G C E I++ EY+E+G + L
Sbjct 516 NPKSQQGLAEFRTEIEMLSQFRHRHLVSLIGYCDENNEMILIYEYMENGTVKSHLYGSGL 575
Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ ++ + A L YL +K ++H +V NILL + K++D
Sbjct 576 PSLTWKQRLEICIGAARGLHYLHTGDSKPVIHRDVKSANILLDE-------NFMAKVADF 628
Query 761 GVGL-GALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA- 813
G+ G + V +L PE L+ D + FG L E+
Sbjct 629 GLSKTGPELDQTHVSTAVKGSFGYLDPEYFR--RQQLTDKSDVYSFGVVLFEVLCARPVI 686
Query 814 ----PLQSRSPSEKEHFYQRQHRLPEPSCPQL 841
P + + +E +Q++ +L + L
Sbjct 687 DPTLPREMVNLAEWAMKWQKKGQLDQIIDQSL 718
>sp|C0LGT5|Y5169_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At5g16900 OS=Arabidopsis thaliana OX=3702
GN=At5g16900 PE=1 SV=1
Length=866
Score = 246 bits (629), Expect = 7e-67, Method: Composition-based stats.
Identities = 67/287 (23%), Positives = 124/287 (43%), Gaps = 17/287 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R +GEG FG V E VAVK L ++ +K E+++L +
Sbjct 571 MTNNFERVIGEGGFGVVYHGYL-----NDSEQVAVKVLSPSSSQGYKE-FKAEVELLLRV 624
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEG 1010
+H +++ G C++Q L L+ EY+ G L+ +L + L A + G
Sbjct 625 HHINLVSLVGYCDEQAH--LALIYEYMANGDLKSHLSGKHGDCVLKWENRLSIAVETALG 682
Query 1011 MAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH+ +HRD+ + N+LLD K+ DFGL+++ G E + +P +
Sbjct 683 LEYLHSGCKPLMVHRDVKSMNILLDEHFQAKLADFGLSRSFSVGEESHVSTGVVGTP-GY 741
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
PE + Y+ SDV+SFG+ L E++T+ + + + + +T ++ +
Sbjct 742 LDPEYYRTYRLTEKSDVYSFGIVLLEIITNQPVLEQA-NENRHIAERVRTMLTRSDISTI 800
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
++ + L +C + RP +++ LK +
Sbjct 801 VDPNLIGEYDSGSVRKALKLAMSCVDPSPVARPDMSHVVQELKQCIK 847
Score = 211 bits (536), Expect = 6e-55, Method: Composition-based stats.
Identities = 74/331 (22%), Positives = 115/331 (35%), Gaps = 66/331 (20%)
Query 571 PRTLNLS-QLSFHRVDQKEI-----TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
P NLS + R+ EI +G+G VY G L
Sbjct 549 PSRANLSLENKKRRITYSEILLMTNNFERVIGEGGFGVVYHGYLNDSE------------ 596
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+V +KVL PS F L+ +V H +L + G C
Sbjct 597 -------------QVAVKVLSPSSSQGYKEFKAEVELLLRVHHINLVSLVGYCDEQAHLA 643
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRN 739
++ EY+ +G L L + G + W ++ +A + A L YL + +VH +V N
Sbjct 644 LIYEYMANGDLKSHLSGKHGDCVLKWENRLSIAVETALGLEYLHSGCKPLMVHRDVKSMN 703
Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLST 793
ILL KL+D G+ EE V +L PE L+
Sbjct 704 ILLDE-------HFQAKLADFGLSRSFSVGEESHVSTGVVGTPGYLDPEYYRT--YRLTE 754
Query 794 AMDKWGFGATLLEICFDG---EAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--------- 841
D + FG LLEI + E ++R +E+ + + P L
Sbjct 755 KSDVYSFGIVLLEIITNQPVLEQANENRHIAERVRTMLTRSDISTIVDPNLIGEYDSGSV 814
Query 842 ---ATLTSQCLTYEPTQRPSFRTILRDLTRL 869
L C+ P RP ++++L +
Sbjct 815 RKALKLAMSCVDPSPVARPDMSHVVQELKQC 845
>sp|A7J1T2|M313A_XENLA Mitogen-activated protein kinase kinase
kinase 13-A OS=Xenopus laevis OX=8355 GN=map3k13-a PE=2 SV=1
Length=961
Score = 248 bits (632), Expect = 8e-67, Method: Composition-based stats.
Identities = 84/301 (28%), Positives = 125/301 (42%), Gaps = 35/301 (12%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ + + + + + +++ LG G G V L + GE VA+K
Sbjct 143 WNIIGKAYSTDYKLQQQETWEVPFEEISELQWLGSGAQGAVFLGKFR------GEEVAIK 196
Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
+ R + +I LR L H +II +KG C L+MEY G L + L
Sbjct 197 KV--------REQKETDIKHLRKLKHPNIIAFKGVCTQA--PCYCLIMEYCAHGQLYEVL 246
Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
+ L+ ++ I GM YLH IHRDL + NVL+ + VKI DFG +K +
Sbjct 247 RAGRKVSPRLLVDWSNGIASGMNYLHLHKIIHRDLKSPNVLVTHTDTVKISDFGTSKELS 306
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
+ + V W APE ++ D+WSFGV L+ELLT P K +
Sbjct 307 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVLLWELLTG-----EIPYKDV 357
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ I G + LP P CP LMK W ++ RP+F ++ L
Sbjct 358 DSSAIIWGVGSN---------SLHLPVPSTCPDGFKILMKQTWHSKPRNRPSFRQILMHL 408
Query 1170 K 1170
Sbjct 409 D 409
Score = 218 bits (554), Expect = 7e-57, Method: Composition-based stats.
Identities = 67/305 (22%), Positives = 110/305 (36%), Gaps = 50/305 (16%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+A L Q V +EI++L LG G + V+ G+ R E
Sbjct 147 GKAYSTDYKLQQQETWEVPFEEISELQWLGSGAQGAVFLGKFRGE--------------- 191
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
V +K + + ++ H ++ GVC + P ++
Sbjct 192 -----------EVAIKKVREQKE-------TDIKHLRKLKHPNIIAFKGVCTQAPCYCLI 233
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
EY HG L LR R P + + +AS ++YL ++H ++ N+L+
Sbjct 234 MEYCAHGQLYEVLRAGRKVSP-RLLVDWSNGIASGMNYLHLHKIIHRDLKSPNVLVTH-- 290
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+ +K+SD G + ++ + W+APE + +S +D W FG
Sbjct 291 -----TDTVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVL 343
Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
L E+ GE P + S +P L Q +P RPSFR
Sbjct 344 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWHSKPRNRPSFR 402
Query 861 TILRD 865
IL
Sbjct 403 QILMH 407
>sp|Q5Z6X0|CIPKP_ORYSJ CBL-interacting protein kinase 25 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK25 PE=2 SV=1
Length=514
Score = 238 bits (607), Expect = 8e-67, Method: Composition-based stats.
Identities = 68/275 (25%), Positives = 119/275 (43%), Gaps = 32/275 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960
+GEG+F KV L + TGE VA+K + + K+EI +++ L H +++
Sbjct 27 VGEGNFAKVYLGRHRA----TGEEVAIKVMDKEKLVRLGATELIKREIAVMQRLRHPNVV 82
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYL 1014
+ ++ + + +VMEYV G+L Y R + + F QQ+ +AY
Sbjct 83 RIHEVMANK--RRICVVMEYVRGGALYRYFRRGPSGGAAGLREHEARRFFQQLVSAVAYC 140
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H++ HRD+ N+L+D +K+ DFGL+ ++ +P+F APE K
Sbjct 141 HSRGVFHRDIKLDNLLVDEQGNLKVADFGLSALADMERREAHLQTVCGTPLF-LAPEVFK 199
Query 1075 EYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ +DVW+ GV LY LLT V RL L+ + +
Sbjct 200 RRGYDGAKADVWACGVVLYVLLTGRKPF---------------PDEHVSRLYRLIGQN-Q 243
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
P ++ L++ + + R T ++ +
Sbjct 244 FQCPPSFSPDLARLVRRLLQPDPDRRITIPEIMEM 278
Score = 184 bits (467), Expect = 3e-48, Method: Composition-based stats.
Identities = 56/298 (19%), Positives = 95/298 (32%), Gaps = 45/298 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ + +G+G VY GR R G V +KV
Sbjct 16 MTTERYEFGPLVGEGNFAKVYLGRHRATGE------------------------EVAIKV 51
Query 644 LDPSHH---DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
+D ++M ++ H ++ +H V +V EYV G L + R
Sbjct 52 MDKEKLVRLGATELIKREIAVMQRLRHPNVVRIHEVMANKRRICVVMEYVRGGALYRYFR 111
Query 701 RERG----HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
R + QQL SA++Y ++ + H ++ N+L+ G +K
Sbjct 112 RGPSGGAAGLREHEARRFFQQLVSAVAYCHSRGVFHRDIKLDNLLVDEQG-------NLK 164
Query 757 LSDPGVG------LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
++D G+ + +LAPE D W G L +
Sbjct 165 VADFGLSALADMERREAHLQTVCGTPLFLAPEVFKRRGYD-GAKADVWACGVVLYVLLTG 223
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ Q Q + P P LA L + L +P +R + I+
Sbjct 224 RKPFPDEHVSRLYRLIGQNQFQCPPSFSPDLARLVRRLLQPDPDRRITIPEIMEMRWF 281
>sp|O65405|CRK28_ARATH Cysteine-rich receptor-like protein kinase
28 OS=Arabidopsis thaliana OX=3702 GN=CRK28 PE=3 SV=2
Length=683
Score = 243 bits (619), Expect = 8e-67, Method: Composition-based stats.
Identities = 77/338 (23%), Positives = 123/338 (36%), Gaps = 28/338 (8%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
+ L + L + + +LG G F
Sbjct 313 WKKNKSVGRVKGNKHNLLLLVIVILLQKDEFSDSLVVDFETLKAATDNFSPENELGRGGF 372
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968
G V + G+ +AVK L G Q S +K EI +L L H ++++ G C +
Sbjct 373 GSVYKGVFSG-----GQEIAVKRLSCTSG-QGDSEFKNEILLLAKLQHRNLVRLLGFCIE 426
Query 969 QGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIH 1021
E+ LV E++ SL +++ R + + G+ YLH IH
Sbjct 427 GQER--ILVYEFIKNASLDNFIFDLKKRQLLDWGVRYKMIGGVARGLLYLHEDSRYRIIH 484
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGH-EYYRVREDGDSPVFWYAPECLKEYKFYY 1080
RDL A N+LLD + KI DFGLAK +R + APE +F
Sbjct 485 RDLKASNILLDQEMNPKIADFGLAKLYDTDQTSTHRFTSKIAGTYGYMAPEYAIYGQFSV 544
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR-------LTELLERGER 1133
+DV+SFGV + E++T ++ E + R + L G R
Sbjct 545 KTDVFSFGVLVIEIITGKGNNNGRSNDDEEAENLLSWVWRCWREDIILSVIDPSLTTGSR 604
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
H+ C + + RPT +++ +L +
Sbjct 605 SEI-----LRCIHIGLLCVQESPASRPTMDSVALMLNS 637
Score = 229 bits (584), Expect = 3e-62, Method: Composition-based stats.
Identities = 58/358 (16%), Positives = 109/358 (30%), Gaps = 65/358 (18%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
+ + + LG+G +VY+G
Sbjct 350 DFETLKAATDNFSPENELGRGGFGSVYKGVFSGGQ------------------------- 384
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+ +K L + F L++++ H +L + G C+ G E I+V E++++ LD
Sbjct 385 EIAVKRLSCTSGQGDSEFKNEILLLAKLQHRNLVRLLGFCIEGQERILVYEFIKNASLDN 444
Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752
++ + + W + + +A L YL ++H ++ NILL +
Sbjct 445 FIFDLKKRQLLDWGVRYKMIGGVARGLLYLHEDSRYRIIHRDLKASNILLDQE------- 497
Query 753 PFIKLSDPGVGLGALSREERV--------ERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
K++D G+ + + ++APE G S D + FG +
Sbjct 498 MNPKIADFGLAKLYDTDQTSTHRFTSKIAGTYGYMAPEYAIYG--QFSVKTDVFSFGVLV 555
Query 805 LEICF-DGEAPLQSRSPSEKEHFYQRQHRLPEPS------CPQLAT-----------LTS 846
+EI G +S E E+ R P L T +
Sbjct 556 IEIITGKGNNNGRSNDDEEAENLLSWVWRCWREDIILSVIDPSLTTGSRSEILRCIHIGL 615
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
C+ P RP+ ++ L + L
Sbjct 616 LCVQESPASRPTMDSVALMLNSYSYTLPTPSRPAFALESVMPSMNVSSSTEPLLMSLN 673
>sp|Q6Z4U4|BAK1_ORYSJ LRR receptor kinase BAK1 OS=Oryza sativa
subsp. japonica OX=39947 GN=BAK1 PE=1 SV=1
Length=624
Score = 241 bits (615), Expect = 8e-67, Method: Composition-based stats.
Identities = 73/324 (23%), Positives = 123/324 (38%), Gaps = 20/324 (6%)
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917
R + +V + LG G FGKV
Sbjct 262 RRRKPQEHFFDVPAEEDPEVHLGQLKRFSLRELQVATDTFSNKNILGRGGFGKVYKGRL- 320
Query 918 PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLV 977
G +VAVK LK + P ++ E++++ H ++++ +G C E+ LV
Sbjct 321 ----ADGSLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTER--LLV 374
Query 978 MEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNV 1029
Y+ GS+ L + A G++YLH IHRD+ A N+
Sbjct 375 YPYMANGSVASRLRERPPSEPPLDWRTRRRIALGSARGLSYLHDHCDPKIIHRDVKAANI 434
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
LLD D +GDFGLAK + + V + APE L K +DV+ +G+
Sbjct 435 LLDEDFEAVVGDFGLAKLMDYKDTH--VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 492
Query 1090 TLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
L EL+T + + + L+ +G + RL L++ + D +
Sbjct 493 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKRLEMLVDPDLQSNYIDVEVESLIQ 552
Query 1147 LMKNCWETEASFRPTFENLIPILK 1170
+ C + + RP ++ +L+
Sbjct 553 VALLCTQGSPTERPKMAEVVRMLE 576
Score = 198 bits (504), Expect = 3e-52, Method: Composition-based stats.
Identities = 71/324 (22%), Positives = 113/324 (35%), Gaps = 67/324 (21%)
Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + S V + + LG+G VY+GRL
Sbjct 285 QLKRFSLRELQVATDTFSNKNILGRGGFGKVYKGRLADGS-------------------- 324
Query 633 RGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
V +K L L F ++S H +L + G C+ E ++V Y+
Sbjct 325 -----LVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMA 379
Query 692 HGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745
+G + LR R P+ W + +A A LSYL + ++H +V NILL
Sbjct 380 NGSVASRLRERPPSEPPLDWRTRRRIALGSARGLSYLHDHCDPKIIHRDVKAANILLDED 439
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800
A + D G+ ++ V I +APE L G + S D +G+
Sbjct 440 FEAV-------VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 490
Query 801 GATLLEICFDGEAPLQSR--SPSEKEHFYQ-----RQHRLPEPSCPQLAT---------- 843
G LLE+ A +R + + ++ RL P L +
Sbjct 491 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKRLEMLVDPDLQSNYIDVEVESL 550
Query 844 --LTSQCLTYEPTQRPSFRTILRD 865
+ C PT+RP ++R
Sbjct 551 IQVALLCTQGSPTERPKMAEVVRM 574
>sp|B8BB68|BAK1_ORYSI LRR receptor kinase BAK1 OS=Oryza sativa
subsp. indica OX=39946 GN=BAK1 PE=2 SV=1
Length=624
Score = 241 bits (615), Expect = 8e-67, Method: Composition-based stats.
Identities = 73/324 (23%), Positives = 123/324 (38%), Gaps = 20/324 (6%)
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917
R + +V + LG G FGKV
Sbjct 262 RRRKPQEHFFDVPAEEDPEVHLGQLKRFSLRELQVATDTFSNKNILGRGGFGKVYKGRL- 320
Query 918 PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLV 977
G +VAVK LK + P ++ E++++ H ++++ +G C E+ LV
Sbjct 321 ----ADGSLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTER--LLV 374
Query 978 MEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNV 1029
Y+ GS+ L + A G++YLH IHRD+ A N+
Sbjct 375 YPYMANGSVASRLRERPPSEPPLDWRTRRRIALGSARGLSYLHDHCDPKIIHRDVKAANI 434
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
LLD D +GDFGLAK + + V + APE L K +DV+ +G+
Sbjct 435 LLDEDFEAVVGDFGLAKLMDYKDTH--VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 492
Query 1090 TLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
L EL+T + + + L+ +G + RL L++ + D +
Sbjct 493 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKRLEMLVDPDLQSNYIDVEVESLIQ 552
Query 1147 LMKNCWETEASFRPTFENLIPILK 1170
+ C + + RP ++ +L+
Sbjct 553 VALLCTQGSPTERPKMAEVVRMLE 576
Score = 198 bits (504), Expect = 3e-52, Method: Composition-based stats.
Identities = 71/324 (22%), Positives = 113/324 (35%), Gaps = 67/324 (21%)
Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + S V + + LG+G VY+GRL
Sbjct 285 QLKRFSLRELQVATDTFSNKNILGRGGFGKVYKGRLADGS-------------------- 324
Query 633 RGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
V +K L L F ++S H +L + G C+ E ++V Y+
Sbjct 325 -----LVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMA 379
Query 692 HGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745
+G + LR R P+ W + +A A LSYL + ++H +V NILL
Sbjct 380 NGSVASRLRERPPSEPPLDWRTRRRIALGSARGLSYLHDHCDPKIIHRDVKAANILLDED 439
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800
A + D G+ ++ V I +APE L G + S D +G+
Sbjct 440 FEAV-------VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 490
Query 801 GATLLEICFDGEAPLQSR--SPSEKEHFYQ-----RQHRLPEPSCPQLAT---------- 843
G LLE+ A +R + + ++ RL P L +
Sbjct 491 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKRLEMLVDPDLQSNYIDVEVESL 550
Query 844 --LTSQCLTYEPTQRPSFRTILRD 865
+ C PT+RP ++R
Sbjct 551 IQVALLCTQGSPTERPKMAEVVRM 574
>sp|O64777|Y1643_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61430 OS=Arabidopsis thaliana OX=3702
GN=At1g61430 PE=2 SV=2
Length=806
Score = 245 bits (625), Expect = 8e-67, Method: Composition-based stats.
Identities = 74/307 (24%), Positives = 120/307 (39%), Gaps = 14/307 (5%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
+ LG G FG V G +AVK L + G Q +
Sbjct 476 FFEMNAIQTATNNFSLSNKLGPGGFGSVYKA--RNGKLQDGREIAVKRLSSSSG-QGKQE 532
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ 999
+ EI ++ L H ++++ GCC + EK L+ ++ SL ++ + + +
Sbjct 533 FMNEIVLISKLQHRNLVRVLGCCVEGTEK--LLIYGFLKNKSLDTFVFDARKKLELDWPK 590
Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
+ I G+ YLH IHRDL N+LLD KI DFGLA+ +G +Y
Sbjct 591 RFEIIEGIARGLLYLHRDSRLRVIHRDLKVSNILLDEKMNPKISDFGLARMF-QGTQYQE 649
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIA 1115
+ + +PE F SD++SFGV L E+++ SS S + L+ A
Sbjct 650 KTRRVVGTLGYMSPEYAWTGVFSEKSDIYSFGVLLLEIISGKKISSFSYGEEGKALLAYA 709
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
R L++ + C + E + RP L+ +L T +
Sbjct 710 WECWCETREVNFLDQALADSSHPSEVGRCVQIGLLCVQHEPADRPNTLELLSMLTTTSDL 769
Query 1176 YQGQAPS 1182
+ P+
Sbjct 770 PLPKKPT 776
Score = 220 bits (560), Expect = 2e-58, Method: Composition-based stats.
Identities = 68/352 (19%), Positives = 120/352 (34%), Gaps = 60/352 (17%)
Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRT-LNLSQLSFHRVDQKEITQLSHLGQGTRT 601
F RC + SN ++ L +++ + + + LG G
Sbjct 442 AAFGFWRCRVEHNAHISNDAWRNFLQSQDVPGLEFFEMNAIQTATNNFSLSNKLGPGGFG 501
Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL 661
+VY+ R G + +K L S F L
Sbjct 502 SVYKARNGKLQDGR----------------------EIAVKRLSSSSGQGKQEFMNEIVL 539
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLA 719
+S++ H +L V G CV G E +++ ++++ LD ++ R + + W + + + +A
Sbjct 540 ISKLQHRNLVRVLGCCVEGTEKLLIYGFLKNKSLDTFVFDARKKLELDWPKRFEIIEGIA 599
Query 720 SALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREER 772
L YL ++H ++ NILL K+SD G+ + R
Sbjct 600 RGLLYLHRDSRLRVIHRDLKVSNILLDEK-------MNPKISDFGLARMFQGTQYQEKTR 652
Query 773 --VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS--------- 821
V + +++PE G S D + FG LLEI + S
Sbjct 653 RVVGTLGYMSPEYAWTGV--FSEKSDIYSFGVLLLEIISGKKISSFSYGEEGKALLAYAW 710
Query 822 ----EKEHFYQRQHRLPEPSCP----QLATLTSQCLTYEPTQRPSFRTILRD 865
E L + S P + + C+ +EP RP+ +L
Sbjct 711 ECWCETREVNFLDQALADSSHPSEVGRCVQIGLLCVQHEPADRPNTLELLSM 762
>sp|O24527|SIK1_ARATH Serine/threonine-protein kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=SIK1 PE=1 SV=1
Length=836
Score = 246 bits (627), Expect = 9e-67, Method: Composition-based stats.
Identities = 78/315 (25%), Positives = 130/315 (41%), Gaps = 26/315 (8%)
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915
PS + + + P S + + +LG+G +G V
Sbjct 208 DPSSSSSKLHGEDNRKMQQQNSKMSTTSLPDSITREDPTTKYEFLNELGKGSYGSV---- 263
Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
Y + T E+VAVK + G + + EI++L+ H ++++Y G QGE L
Sbjct 264 YKARDLKTSEIVAVKVISLTEGEEGYEEIRGEIEMLQQCNHPNVVRYLGSY--QGEDYLW 321
Query 976 LVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033
+VMEY GS+ D + ++ Q+ ++ +G+AYLH+ + +HRD+ N+LL
Sbjct 322 IVMEYCGGGSVADLMNVTEEALEEYQIAYICREALKGLAYLHSIYKVHRDIKGGNILLTE 381
Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
VK+GDFG+A + R W APE ++E ++ DVW+ GV+ E
Sbjct 382 QGEVKLGDFGVAAQL---TRTMSKRNTFIGTPHWMAPEVIQENRYDGKVDVWALGVSAIE 438
Query 1094 LLTHCDSSQSP-PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152
+ S P + L +I I M L +K + + C
Sbjct 439 MAEGLPPRSSVHPMRVLFMISIEPAPM--------------LEDKEKWSLVFHDFVAKCL 484
Query 1153 ETEASFRPTFENLIP 1167
E RPT ++
Sbjct 485 TKEPRLRPTAAEMLK 499
Score = 203 bits (517), Expect = 1e-52, Method: Composition-based stats.
Identities = 61/333 (18%), Positives = 108/333 (32%), Gaps = 43/333 (13%)
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
M+ + T +L + L+ LG+G+ +VY+
Sbjct 224 MQQQNSKMSTTSLPDSITREDPTTKYEFLNELGKGSYGSVYKA----------------- 266
Query 624 EDPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
RD V +KV+ + ++ Q +H ++ G
Sbjct 267 -------RDLKTSEIVAVKVISLTEGEEGYEEIRGEIEMLQQCNHPNVVRYLGSYQGEDY 319
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+V EY G + + + + ++ L+YL + VH ++ G NILL
Sbjct 320 LWIVMEYCGGGSVADLMNVTEEALEEYQIAYICREALKGLAYLHSIYKVHRDIKGGNILL 379
Query 743 ARLGLAEGTSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKW 798
G +KL D GV R + W+APE + N +D W
Sbjct 380 TEQGE-------VKLGDFGVAAQLTRTMSKRNTFIGTPHWMAPEVIQE--NRYDGKVDVW 430
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP----EPSCPQLATLTSQCLTYEPT 854
G + +E+ +G P S P + E ++CLT EP
Sbjct 431 ALGVSAIEMA-EGLPPRSSVHPMRVLFMISIEPAPMLEDKEKWSLVFHDFVAKCLTKEPR 489
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
RP+ +L+ + A ++ +
Sbjct 490 LRPTAAEMLKHKFVERCKTGASAMSPKIEKSRQ 522
>sp|Q94F62|BAK1_ARATH BRASSINOSTEROID INSENSITIVE 1-associated
receptor kinase 1 OS=Arabidopsis thaliana OX=3702 GN=BAK1 PE=1
SV=2
Length=615
Score = 241 bits (614), Expect = 9e-67, Method: Composition-based stats.
Identities = 71/325 (22%), Positives = 125/325 (38%), Gaps = 20/325 (6%)
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916
+ + +V + LG G FGKV
Sbjct 249 WRRKKPQDHFFDVPAEEDPEVHLGQLKRFSLRELQVASDNFSNKNILGRGGFGKVYKGRL 308
Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976
G +VAVK LK + ++ E++++ H ++++ +G C E+ L
Sbjct 309 -----ADGTLVAVKRLKEERTQGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTER--LL 361
Query 977 VMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028
V Y+ GS+ L + + A G+AYLH IHRD+ A N
Sbjct 362 VYPYMANGSVASCLRERPESQPPLDWPKRQRIALGSARGLAYLHDHCDPKIIHRDVKAAN 421
Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
+LLD + +GDFGLAK + + V + APE L K +DV+ +G
Sbjct 422 ILLDEEFEAVVGDFGLAKLMDYKDTH--VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 479
Query 1089 VTLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
V L EL+T + + + L+ +G + +L L++ + D+ ++
Sbjct 480 VMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEALVDVDLQGNYKDEEVEQLI 539
Query 1146 HLMKNCWETEASFRPTFENLIPILK 1170
+ C ++ RP ++ +L+
Sbjct 540 QVALLCTQSSPMERPKMSEVVRMLE 564
Score = 202 bits (515), Expect = 7e-54, Method: Composition-based stats.
Identities = 71/365 (19%), Positives = 117/365 (32%), Gaps = 70/365 (19%)
Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + S V + + LG+G VY+GRL
Sbjct 273 QLKRFSLRELQVASDNFSNKNILGRGGFGKVYKGRLADG--------------------- 311
Query 633 RGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
V +K L L F ++S H +L + G C+ E ++V Y+
Sbjct 312 ----TLVAVKRLKEERTQGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMA 367
Query 692 HGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745
+G + LR R P+ W + +A A L+YL + ++H +V NILL
Sbjct 368 NGSVASCLRERPESQPPLDWPKRQRIALGSARGLAYLHDHCDPKIIHRDVKAANILLDEE 427
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800
A + D G+ ++ V I +APE L G + S D +G+
Sbjct 428 FEAV-------VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 478
Query 801 GATLLEICFDGEAPLQSR--SPSEKEHFYQRQHRLPEPSCPQLAT--------------- 843
G LLE+ A +R + + + L E L
Sbjct 479 GVMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEALVDVDLQGNYKDEEVEQL 538
Query 844 --LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901
+ C P +RP + + L+ LA+ + + +
Sbjct 539 IQVALLCTQSSPMERPKMSEV---VRMLEGDGLAERWEEWQKEEMFRQDFNYPTHHPAVS 595
Query 902 DLGEG 906
G
Sbjct 596 GWIIG 600
>sp|Q9CAL8|PEK13_ARATH Proline-rich receptor-like protein kinase
PERK13 OS=Arabidopsis thaliana OX=3702 GN=PERK13 PE=1 SV=1
Length=710
Score = 243 bits (620), Expect = 9e-67, Method: Composition-based stats.
Identities = 81/305 (27%), Positives = 125/305 (41%), Gaps = 21/305 (7%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ + K LGEG FG V G++VAVK LK G
Sbjct 334 MGSGQTHFTYEELTDITEGFSKHNILGEGGFGCVYKG-----KLNDGKLVAVKQLKVGSG 388
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHS 994
R +K E++I+ ++H H++ G C E+ L+ EYVP +L +L R
Sbjct 389 QGDRE-FKAEVEIISRVHHRHLVSLVGYCIADSER--LLIYEYVPNQTLEHHLHGKGRPV 445
Query 995 IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
+ A+ + A +G+AYLH IHRD+ + N+LLD++ ++ DFGLAK
Sbjct 446 LEWARRVRIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDDEFEAQVADFGLAKLNDST 505
Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLE 1110
+ R + APE + K SDV+SFGV L EL+T Q P
Sbjct 506 QTHVSTR--VMGTFGYLAPEYAQSGKLTDRSDVFSFGVVLLELITGRKPVDQYQPLGEES 563
Query 1111 LIGIAQG----QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L+ A+ + +EL++R + + C RP ++
Sbjct 564 LVEWARPLLHKAIETGDFSELVDRRLEKHYVENEVFRMIETAAACVRHSGPKRPRMVQVV 623
Query 1167 PILKT 1171
L +
Sbjct 624 RALDS 628
Score = 224 bits (572), Expect = 2e-60, Method: Composition-based stats.
Identities = 64/307 (21%), Positives = 110/307 (36%), Gaps = 46/307 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ ++ + LG+G VY+G+L V +K L
Sbjct 350 TEGFSKHNILGEGGFGCVYKGKLNDGK-------------------------LVAVKQLK 384
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RG 704
F ++S+V H HL + G C+ E +++ EYV + L+ L + R
Sbjct 385 VGSGQGDREFKAEVEIISRVHHRHLVSLVGYCIADSERLLIYEYVPNQTLEHHLHGKGRP 444
Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
+ A ++ +A A L+YL ++H ++ NILL A+ ++D G
Sbjct 445 VLEWARRVRIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDDEFEAQ-------VADFG 497
Query 762 VGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
+ S + V +LAPE G L+ D + FG LLE+ G P+
Sbjct 498 LAKLNDSTQTHVSTRVMGTFGYLAPEYAQSG--KLTDRSDVFSFGVVLLELI-TGRKPVD 554
Query 817 SRSPSEKEHFYQRQHRLPEPSCP--QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
P +E + L + + L + L + FR I ++
Sbjct 555 QYQPLGEESLVEWARPLLHKAIETGDFSELVDRRLEKHYVENEVFRMIETAAACVRHSGP 614
Query 875 ADVLTVN 881
V
Sbjct 615 KRPRMVQ 621
>sp|Q8H199|CRK14_ARATH Cysteine-rich receptor-like protein kinase
14 OS=Arabidopsis thaliana OX=3702 GN=CRK14 PE=2 SV=2
Length=658
Score = 241 bits (616), Expect = 1e-66, Method: Composition-based stats.
Identities = 75/292 (26%), Positives = 123/292 (42%), Gaps = 29/292 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG+V + G VA+K L Q +K E+ ++ L+H +++K
Sbjct 343 IGRGGFGEVFMGVL------NGTEVAIKRLSK-ASRQGAREFKNEVVVVAKLHHRNLVKL 395
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
G C + EK LV E+VP SL +L + + + + I G+ YLH
Sbjct 396 LGFCLEGEEK--ILVYEFVPNKSLDYFLFDPTKQGQLDWTKRYNIIRGITRGILYLHQDS 453
Query 1019 ---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
IHRDL A N+LLD D KI DFG+A+ ++ + PE +++
Sbjct 454 RLTIIHRDLKASNILLDADMNPKIADFGMARIFGIDQSGANTKKIA-GTRGYMPPEYVRQ 512
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+F SDV+SFGV + E++ ++ T L+ A EL++
Sbjct 513 GQFSTRSDVYSFGVLVLEIICGRNNRFIHQSDTTVENLVTYAWRLWRNDSPLELVD---- 568
Query 1134 LPRPDKCPCE----VYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
+ C E H+ C + + RP+ + +L ++ Y P
Sbjct 569 PTISENCETEEVTRCIHIALLCVQHNPTDRPSLSTINMML--INNSYVLPDP 618
Score = 238 bits (607), Expect = 2e-65, Method: Composition-based stats.
Identities = 62/351 (18%), Positives = 119/351 (34%), Gaps = 66/351 (19%)
Query 565 RGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
+G+ + Q F ++ + ++ + +G+G V+ G L
Sbjct 311 QGSSTDITITHSLQFDFKAIEDATNKFSESNIIGRGGFGEVFMGVL-------------- 356
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
V +K L + A F +++++ H +L + G C+ G E
Sbjct 357 ------------NGTEVAIKRLSKASRQGAREFKNEVVVVAKLHHRNLVKLLGFCLEGEE 404
Query 683 NIMVTEYVEHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCG 737
I+V E+V + LD +L ++G + + + + + + YL + ++H ++
Sbjct 405 KILVYEFVPNKSLDYFLFDPTKQGQLDWTKRYNIIRGITRGILYLHQDSRLTIIHRDLKA 464
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSL 791
NILL K++D G+ + ++ ++ PE + G
Sbjct 465 SNILLD-------ADMNPKIADFGMARIFGIDQSGANTKKIAGTRGYMPPEYVRQG--QF 515
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------ 839
ST D + FG +LEI +S + E+ RL P
Sbjct 516 STRSDVYSFGVLVLEIICGRNNRFIHQSDTTVENLVTYAWRLWRNDSPLELVDPTISENC 575
Query 840 ------QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884
+ + C+ + PT RPS TI L
Sbjct 576 ETEEVTRCIHIALLCVQHNPTDRPSLSTINMMLINNSYVLPDPQQPGFFFP 626
>sp|Q7X8C5|WAKLB_ARATH Wall-associated receptor kinase-like 2
OS=Arabidopsis thaliana OX=3702 GN=WAKL2 PE=2 SV=1
Length=748
Score = 244 bits (622), Expect = 1e-66, Method: Composition-based stats.
Identities = 76/293 (26%), Positives = 119/293 (41%), Gaps = 18/293 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
K R LG+G G V G +VAVK KA + E+ +L +
Sbjct 414 DNFNKNRVLGQGGQGTVYKGML-----VDGRIVAVKRSKA-VDEDRVEEFINEVVVLAQI 467
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEG 1010
H +I+K GCC + + LV E+VP G L L S + L A +I
Sbjct 468 NHRNIVKLLGCCLET--EVPVLVYEFVPNGDLCKRLHDESDDYTMTWEVRLHIAIEIAGA 525
Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
++YLH+ HRD+ N+LLD K+ DFG +++V + + G +
Sbjct 526 LSYLHSAASFPIYHRDIKTTNILLDERNRAKVSDFGTSRSVTIDQTHLTTQVAG--TFGY 583
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
PE + KF SDV+SFGV L ELLT SS+ + L + R+ +
Sbjct 584 VDPEYFQSSKFTEKSDVYSFGVVLVELLTGEKPSSRVRSEENRGLAAHFVEAVKENRVLD 643
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+++ + V +L + C + RP + L+ + +
Sbjct 644 IVDDRIKDECNMDQVMSVANLARRCLNRKGKKRPNMREVSIELEMIRSSHYDS 696
Score = 224 bits (571), Expect = 5e-60, Method: Composition-based stats.
Identities = 62/323 (19%), Positives = 111/323 (34%), Gaps = 63/323 (20%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ LGQG + VY+G L V +K
Sbjct 412 ATDNFNKNRVLGQGGQGTVYKGMLVDGRI-------------------------VAVKRS 446
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D F +++Q++H ++ + G C+ ++V E+V +G L L E
Sbjct 447 KAVDEDRVEEFINEVVVLAQINHRNIVKLLGCCLETEVPVLVYEFVPNGDLCKRLHDESD 506
Query 705 HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
M W ++ +A ++A ALSYL + + H ++ NILL A K+SD
Sbjct 507 DYTMTWEVRLHIAIEIAGALSYLHSAASFPIYHRDIKTTNILLDERNRA-------KVSD 559
Query 760 PGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G + ++ PE ++ + D + FG L+E+ GE P
Sbjct 560 FGTSRSVTIDQTHLTTQVAGTFGYVDPEYFQ--SSKFTEKSDVYSFGVVLVELL-TGEKP 616
Query 815 LQSRSPSEKEHFYQR--------------QHRLPEPSCPQ----LATLTSQCLTYEPTQR 856
E R+ + +A L +CL + +R
Sbjct 617 SSRVRSEENRGLAAHFVEAVKENRVLDIVDDRIKDECNMDQVMSVANLARRCLNRKGKKR 676
Query 857 PSFRTILRDLTRLQPHNLADVLT 879
P+ R + +L ++ + +
Sbjct 677 PNMREVSIELEMIRSSHYDSGIH 699
>sp|Q55EC7|GEFX_DICDI RasGEF domain-containing serine/threonine-protein
kinase X OS=Dictyostelium discoideum OX=44689 GN=gefX
PE=2 SV=1
Length=960
Score = 247 bits (631), Expect = 1e-66, Method: Composition-based stats.
Identities = 72/294 (24%), Positives = 125/294 (43%), Gaps = 23/294 (8%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
P L+ +G+G FG V CY + VA+K ++ P++
Sbjct 9 PTQAIWDIPFESLEFNEKIGKGSFGSVFRGCYLGLD------VAIKKIEKADDPEYLKYI 62
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLF 1003
+E+ +L++L H I+ + G C L +V E+V G +R L + IG + +
Sbjct 63 DREVSMLQSLRHPFIVNFSGICVHSS--GLYIVTEFVSGGDVRQLLKKTPPIGWDKRVSI 120
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
A + + M +LHA+ IHRDL ++N+LLD + +++ DFG A+ + + +
Sbjct 121 AVDLAKAMVFLHAKKIIHRDLKSKNILLDEFQRIRLCDFGFARMSEQTKKSRHMTM--CG 178
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
W APE L + + DV+S+GV L EL+T G+ +
Sbjct 179 TEGWVAPEILLGMSYDTSCDVFSYGVVLAELITGRKP------------GVDLWVRSPET 226
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
++ + CP E+ + C E RP F+ ++ LK +
Sbjct 227 CFDINPEELKQKSIPGCPSELISVCVECCLYEPLTRPKFDEILSQLKVCQNNLK 280
Score = 197 bits (500), Expect = 3e-50, Method: Composition-based stats.
Identities = 64/311 (21%), Positives = 113/311 (36%), Gaps = 48/311 (15%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + + + + +G+G+ +V+ G
Sbjct 5 DPGLPTQAIWDIPFESLEFNEKIGKGSFGSVFRGCYLG---------------------- 42
Query 633 RGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
L V +K + + S++ + H + G+CV +VTE+V
Sbjct 43 ----LDVAIKKIEKADDPEYLKYIDREVSMLQSLRHPFIVNFSGICVHSSGLYIVTEFVS 98
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G + L++ + ++ +A LA A+ +L K ++H ++ +NILL
Sbjct 99 GGDVRQLLKKT-PPIGWDKRVSIAVDLAKAMVFLHAKKIIHRDLKSKNILLDEFQR---- 153
Query 752 SPFIKLSDPGVGLGALSRE-----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
I+L D G + + W+APE L G S T+ D + +G L E
Sbjct 154 ---IRLCDFGFARMSEQTKKSRHMTMCGTEGWVAPEILLGM--SYDTSCDVFSYGVVLAE 208
Query 807 ICFDGEA--PLQSRSPSEKEHFYQ---RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861
+ + L RSP +Q +P +L ++ +C YEP RP F
Sbjct 209 LITGRKPGVDLWVRSPETCFDINPEELKQKSIPGCPS-ELISVCVECCLYEPLTRPKFDE 267
Query 862 ILRDLTRLQPH 872
IL L Q +
Sbjct 268 ILSQLKVCQNN 278
>sp|Q9SIT1|TMK3_ARATH Receptor-like kinase TMK3 OS=Arabidopsis
thaliana OX=3702 GN=TMK3 PE=1 SV=1
Length=943
Score = 247 bits (631), Expect = 1e-66, Method: Composition-based stats.
Identities = 75/285 (26%), Positives = 122/285 (43%), Gaps = 24/285 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961
LG G FG V G +AVK +++ + + +K EI +L + H H++
Sbjct 591 LGRGGFGTVYKGEL-----HDGTKIAVKRMESSVVSDKGLTEFKSEITVLTKMRHRHLVA 645
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------RHSIGLAQLLLFAQQICEGMAYLH 1015
G C D E+ LV EY+P G+L +L R + + L A + G+ YLH
Sbjct 646 LLGYCLDGNER--LLVYEYMPQGTLSQHLFHWKEEGRKPLDWTRRLAIALDVARGVEYLH 703
Query 1016 ---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Q +IHRDL N+LL +D K+ DFGL + P+G Y + + APE
Sbjct 704 TLAHQSFIHRDLKPSNILLGDDMRAKVSDFGLVRLAPDGK--YSIETRVAGTFGYLAPEY 761
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQ---GQMTVLRLTELL 1128
+ D++S GV L EL+T + ++ P + L+ + +
Sbjct 762 AVTGRVTTKVDIFSLGVILMELITGRKALDETQPEDSVHLVTWFRRVAASKDENAFKNAI 821
Query 1129 ERGERLPRPDKCPCE-VYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ L E V+ L +C E RP +++ +L ++
Sbjct 822 DPNISLDDDTVASIEKVWELAGHCCAREPYQRPDMAHIVNVLSSL 866
Score = 221 bits (563), Expect = 4e-58, Method: Composition-based stats.
Identities = 72/345 (21%), Positives = 123/345 (36%), Gaps = 71/345 (21%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ + LG+G VY+G L ++ +K ++
Sbjct 582 TNNFSEENILGRGGFGTVYKGELHDG-------------------------TKIAVKRME 616
Query 646 PS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--R 701
S F ++++++ H HL + G C+ G E ++V EY+ G L L +
Sbjct 617 SSVVSDKGLTEFKSEITVLTKMRHRHLVALLGYCLDGNERLLVYEYMPQGTLSQHLFHWK 676
Query 702 ERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
E G P+ W ++ +A +A + YL +++ +H ++ NILL G K
Sbjct 677 EEGRKPLDWTRRLAIALDVARGVEYLHTLAHQSFIHRDLKPSNILL-------GDDMRAK 729
Query 757 LSDPGVGL----GALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
+SD G+ G S E RV +LAPE G ++T +D + G L+E+ G
Sbjct 730 VSDFGLVRLAPDGKYSIETRVAGTFGYLAPEYAVTG--RVTTKVDIFSLGVILMELI-TG 786
Query 812 EAPLQSRSPSEKEHFYQRQHRL----------------------PEPSCPQLATLTSQCL 849
L P + H R+ S ++ L C
Sbjct 787 RKALDETQPEDSVHLVTWFRRVAASKDENAFKNAIDPNISLDDDTVASIEKVWELAGHCC 846
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894
EP QRP I+ L+ L + +
Sbjct 847 AREPYQRPDMAHIVNVLSSLTVQWKPTETDPDDVYGIDYDMPLPQ 891
>sp|Q8L4H4|NORK_MEDTR Nodulation receptor kinase OS=Medicago truncatula
OX=3880 GN=NORK PE=1 SV=2
Length=925
Score = 247 bits (630), Expect = 1e-66, Method: Composition-based stats.
Identities = 73/278 (26%), Positives = 126/278 (45%), Gaps = 18/278 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG V D G+ VAVK ++ Q + E+++L + HE+++
Sbjct 602 IGEGGFGSVYRGTLD-----DGQEVAVKV-RSSTSTQGTREFDNELNLLSAIQHENLVPL 655
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHA- 1016
G C + ++ LV ++ GSL D L R + L A G+AYLH
Sbjct 656 LGYCNEYDQQ--ILVYPFMSNGSLLDRLYGEASKRKILDWPTRLSIALGAARGLAYLHTF 713
Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+ IHRD+ + N+LLD K+ DFG +K P+ + Y V + + PE K
Sbjct 714 PGRSVIHRDVKSSNILLDQSMCAKVADFGFSKYAPQEGDSY-VSLEVRGTAGYLDPEYYK 772
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ SDV+SFGV L E+++ + P L+ A+ + ++ E+++ G +
Sbjct 773 TQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRIEWSLVEWAKPYIRASKVDEIVDPGIK 832
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ V + C E +++RP +++ L+
Sbjct 833 GGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELED 870
Score = 219 bits (558), Expect = 2e-57, Method: Composition-based stats.
Identities = 83/392 (21%), Positives = 135/392 (34%), Gaps = 100/392 (26%)
Query 500 LRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETS 559
R R I LEG+G+++P + +L + DD F
Sbjct 544 CRYRHKSI-------TLEGFGKTYPMATNIIFSLP-----SKDDFFI------------- 578
Query 560 NLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEG 619
+++++ + ++Q + +G+G +VY G L
Sbjct 579 ------------KSVSVKPFTLEYIEQATEQYKTLIGEGGFGSVYRGTL----------- 615
Query 620 KMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR 679
D GQE V +KV + F +L+S + H +L + G C
Sbjct 616 ------------DDGQE--VAVKVRSSTSTQGTREFDNELNLLSAIQHENLVPLLGYCNE 661
Query 680 GPENIMVTEYVEHGPLDVWLRRE---RGHVPMAWKMVVAQQLASALSYLEN---KNLVHG 733
+ I+V ++ +G L L E R + ++ +A A L+YL ++++H
Sbjct 662 YDQQILVYPFMSNGSLLDRLYGEASKRKILDWPTRLSIALGAARGLAYLHTFPGRSVIHR 721
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGG 787
+V NILL + S K++D G + E +L PE
Sbjct 722 DVKSSNILLDQ-------SMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKT- 773
Query 788 ANSLSTAMDKWGFGATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCP--- 839
LS D + FG LLEI E P S E Y R ++ E P
Sbjct 774 -QQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRIEWSLVEWAKPYIRASKVDEIVDPGIK 832
Query 840 ---------QLATLTSQCLTYEPTQRPSFRTI 862
++ + QCL T RP I
Sbjct 833 GGYHAEALWRVVEVALQCLEPYSTYRPCMVDI 864
>sp|B0LT89|STK24_RAT Serine/threonine-protein kinase 24 OS=Rattus
norvegicus OX=10116 GN=Stk24 PE=2 SV=1
Length=431
Score = 235 bits (599), Expect = 1e-66, Method: Composition-based stats.
Identities = 70/266 (26%), Positives = 121/266 (45%), Gaps = 24/266 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G FG+V + ++ T ++VA+K + + +QEI +L ++ K
Sbjct 29 KIGKGSFGEV----FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTK 84
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
Y G + L ++MEY+ GS D L + Q+ ++I +G+ YLH++ IH
Sbjct 85 YYGSYLKDTK--LWIIMEYLGGGSALDLLEPGPLDEIQIATILREILKGLDYLHSEKKIH 142
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RD+ A NVLL VK+ DFG+A + + R FW APE +K+ +
Sbjct 143 RDIKAANVLLSEHGEVKLADFGVAGQLTD---TQIKRNTFVGTPFWMAPEVIKQSAYDSK 199
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
+D+WS G+T EL + PP ++ +++ L+ +
Sbjct 200 ADIWSLGITAIEL-----AKGEPP----------HSELHPMKVLFLIPKNNPPTLEGSYS 244
Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167
+ ++ C E SFRPT + L+
Sbjct 245 RPLKEFVEACLNKEPSFRPTAKELLK 270
Score = 213 bits (542), Expect = 5e-59, Method: Composition-based stats.
Identities = 63/310 (20%), Positives = 119/310 (38%), Gaps = 44/310 (14%)
Query 570 SPRTLNLSQLSFHRVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
SP L + + D +E T+L +G+G+ V++G
Sbjct 4 SPVQSGLPGMQTLKADPEELFTKLEKIGKGSFGEVFKGI--------------------- 42
Query 629 PGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
D + V +K++D D + +++SQ ++ +G ++ + ++
Sbjct 43 ---DNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIM 99
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
EY+ G L E G + + +++ L YL ++ +H ++ N+LL+ G
Sbjct 100 EYLGGGSALDLL--EPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE 157
Query 748 AEGTSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+KL+D GV + R V W+APE + A + D W G T
Sbjct 158 -------VKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSA--YDSKADIWSLGIT 208
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861
+E+ GE P P + + + L L CL EP+ RP+ +
Sbjct 209 AIELA-KGEPPHSELHPMKVLFLIPKNNPPTLEGSYSRPLKEFVEACLNKEPSFRPTAKE 267
Query 862 ILRDLTRLQP 871
+L+ ++
Sbjct 268 LLKHKFIIRN 277
>sp|Q8L7G3|CRK7_ARATH Cysteine-rich receptor-like protein kinase
7 OS=Arabidopsis thaliana OX=3702 GN=CRK7 PE=2 SV=1
Length=659
Score = 241 bits (615), Expect = 1e-66, Method: Composition-based stats.
Identities = 69/280 (25%), Positives = 113/280 (40%), Gaps = 17/280 (6%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G G FG V + G VAVK L Q + +K E+ ++ L H+++
Sbjct 339 NNKIGRGGFGDVYKGTF-----SNGTEVAVKRLSK-TSEQGDTEFKNEVVVVANLRHKNL 392
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015
++ G ++ E+ LV EYV SL ++L + + Q I G+ YLH
Sbjct 393 VRILGFSIEREER--ILVYEYVENKSLDNFLFDPAKKGQLYWTQRYHIIGGIARGILYLH 450
Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
IHRDL A N+LLD D KI DFG+A+ + +PE
Sbjct 451 QDSRLTIIHRDLKASNILLDADMNPKIADFGMARIFGMDQTQQNTSR-IVGTYGYMSPEY 509
Query 1073 LKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+F SDV+SFGV + E+++ ++S +L+ A +L++
Sbjct 510 AMRGQFSMKSDVYSFGVLVLEIISGRKNNSFIETDDAQDLVTHAWRLWRNGTALDLVDPF 569
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
H+ C + + RP + +L +
Sbjct 570 IADSCRKSEVVRCTHIGLLCVQEDPVKRPAMSTISVMLTS 609
Score = 231 bits (588), Expect = 5e-63, Method: Composition-based stats.
Identities = 61/354 (17%), Positives = 116/354 (33%), Gaps = 66/354 (19%)
Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTR 600
F C + + + T+ QL + + + ++ + +G+G
Sbjct 288 LIFIAGYCFFAKRAKKTYGTTPALDEDDKTTIESLQLDYRAIQAATNDFSENNKIGRGGF 347
Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660
+VY+G V +K L + F
Sbjct 348 GDVYKGT-------------------------FSNGTEVAVKRLSKTSEQGDTEFKNEVV 382
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR--ERGHVPMAWKMVVAQQL 718
+++ + H +L + G + E I+V EYVE+ LD +L ++G + + + +
Sbjct 383 VVANLRHKNLVRILGFSIEREERILVYEYVENKSLDNFLFDPAKKGQLYWTQRYHIIGGI 442
Query 719 ASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSR 769
A + YL + ++H ++ NILL K++D G+ +
Sbjct 443 ARGILYLHQDSRLTIIHRDLKASNILLD-------ADMNPKIADFGMARIFGMDQTQQNT 495
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
V +++PE G S D + FG +LEI G + +
Sbjct 496 SRIVGTYGYMSPEYAMRG--QFSMKSDVYSFGVLVLEIIS-GRKNNSFIETDDAQDLVTH 552
Query 830 QHRLPEP------SCPQLAT------------LTSQCLTYEPTQRPSFRTILRD 865
RL P +A + C+ +P +RP+ TI
Sbjct 553 AWRLWRNGTALDLVDPFIADSCRKSEVVRCTHIGLLCVQEDPVKRPAMSTISVM 606
>sp|P48025|KSYK_MOUSE Tyrosine-protein kinase SYK OS=Mus musculus
OX=10090 GN=Syk PE=1 SV=2
Length=629
Score = 240 bits (613), Expect = 1e-66, Method: Composition-based stats.
Identities = 102/325 (31%), Positives = 148/325 (46%), Gaps = 23/325 (7%)
Query 851 YEPTQRPS--FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
YEPT P R + R+ + + + + + +LG G+F
Sbjct 317 YEPTGGPWGPDRGLQREALPMDTEVYESPYADPEEIRPKEVYLDRSLLTLEDNELGSGNF 376
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
G V Y V + LK + P + E ++++ L + +I++ G CE
Sbjct 377 GTVKKGYYQMKKVVKTVAVKI--LKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICE 434
Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
+S LVME LG L YL ++ I ++ Q+ GM YL +++HRDLAA
Sbjct 435 ---AESWMLVMEMAELGPLNKYLQQNRHIKDKNIIELVHQVSMGMKYLEESNFVHRDLAA 491
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RNVLL KI DFGL+KA+ YY+ + G PV WYAPEC+ YKF SDVWS
Sbjct 492 RNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWS 551
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
FGV ++E ++ M +T +LE+GER+ P CP E+Y
Sbjct 552 FGVLMWEAFSYGQK--------------PYRGMKGSEVTAMLEKGERMGCPAGCPREMYD 597
Query 1147 LMKNCWETEASFRPTFENLIPILKT 1171
LM CW + RP F + L+
Sbjct 598 LMNLCWTYDVENRPGFTAVELRLRN 622
Score = 207 bits (528), Expect = 2e-55, Method: Composition-based stats.
Identities = 65/290 (22%), Positives = 115/290 (40%), Gaps = 40/290 (14%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ + LG G V +G +++ K+ + P LK
Sbjct 367 EDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDP----------ALK-------- 408
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
A++M Q+ + ++ + G+C ++V E E GPL+ +L++ R H+
Sbjct 409 --DELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNR-HIKDKN 464
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ + Q++ + YLE N VH ++ RN+LL T + K+SD G+ + E
Sbjct 465 IIELVHQVSMGMKYLEESNFVHRDLAARNVLL-------VTQHYAKISDFGLSKALRADE 517
Query 771 ERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ + W APEC+ S+ D W FG + E G+ P + SE
Sbjct 518 NYYKAQTHGKWPVKWYAPECI--NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEV 575
Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
++ R+ P ++ L + C TY+ RP F + L
Sbjct 576 TAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFTAVELRLRNYYY 625
Score = 37.4 bits (85), Expect = 0.86, Method: Composition-based stats.
Identities = 21/107 (20%), Positives = 35/107 (33%), Gaps = 15/107 (14%)
Query 453 GPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQ 509
G + + L DGLYL+ S ++ L+VA +A + IE+
Sbjct 17 GNITREEAEDYLVQGGMTDGLYLLRQSRNYLGGFALSVAHNRKA---------HHYTIER 67
Query 510 QDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPG 556
+ GR+ S +L L++ PG
Sbjct 68 ELNGTYAISGGRAHASPADL---CHYHSQEPDGLICLLKKPFNRPPG 111
>sp|Q9M2S4|LRKS4_ARATH L-type lectin-domain containing receptor
kinase S.4 OS=Arabidopsis thaliana OX=3702 GN=LECRKS4 PE=2
SV=1
Length=684
Score = 242 bits (617), Expect = 1e-66, Method: Composition-based stats.
Identities = 78/291 (27%), Positives = 126/291 (43%), Gaps = 22/291 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FGKV Y G+ E VAVK + + Q + E+ + L H ++++
Sbjct 352 LGSGGFGKV----YKGKLPGSDEFVAVKRISHE-SRQGVREFMSEVSSIGHLRHRNLVQL 406
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA-- 1016
G C + + L LV +++P GSL YL + + Q + + G+ YLH
Sbjct 407 LGWCRRRDD--LLLVYDFMPNGSLDMYLFDENPEVILTWKQRFKIIKGVASGLLYLHEGW 464
Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
Q IHRD+ A NVLLD++ ++GDFGLAK G + R + APE K
Sbjct 465 EQTVIHRDIKAANVLLDSEMNGRVGDFGLAKLYEHGSDPGATR--VVGTFGYLAPELTKS 522
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
K ++DV++FG L E+ + S + L ++ + + ++++R
Sbjct 523 GKLTTSTDVYAFGAVLLEVACGRRPIETSALPEELVMVDWVWSRWQSGDIRDVVDRRLNG 582
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
++ V L C RPT ++ L+ Q +P V
Sbjct 583 EFDEEEVVMVIKLGLLCSNNSPEVRPTMRQVVMYLEK-----QFPSPEVVP 628
Score = 219 bits (557), Expect = 1e-58, Method: Composition-based stats.
Identities = 61/308 (20%), Positives = 104/308 (34%), Gaps = 60/308 (19%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
LG G VY+G+L G + V +K +
Sbjct 342 ATNGFGDKELLGSGGFGKVYKGKL------------------------PGSDEFVAVKRI 377
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
F S + + H +L + G C R + ++V +++ +G LD++L E
Sbjct 378 SHESRQGVREFMSEVSSIGHLRHRNLVQLLGWCRRRDDLLLVYDFMPNGSLDMYLFDENP 437
Query 705 HVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
V + W + + + +AS L YL + ++H ++ N+LL + ++ D
Sbjct 438 EVILTWKQRFKIIKGVASGLLYLHEGWEQTVIHRDIKAANVLLD-------SEMNGRVGD 490
Query 760 PGVGLGALSREE-----RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ + V +LAPE G L+T+ D + FGA LLE+
Sbjct 491 FGLAKLYEHGSDPGATRVVGTFGYLAPELTKSG--KLTTSTDVYAFGAVLLEVACGRRPI 548
Query 815 LQSRSPSEKEHFYQR-----------------QHRLPEPSCPQLATLTSQCLTYEPTQRP 857
S P E E + L C P RP
Sbjct 549 ETSALPEELVMVDWVWSRWQSGDIRDVVDRRLNGEFDEEEVVMVIKLGLLCSNNSPEVRP 608
Query 858 SFRTILRD 865
+ R ++
Sbjct 609 TMRQVVMY 616
>sp|O64770|Y1649_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61490 OS=Arabidopsis thaliana OX=3702
GN=At1g61490 PE=3 SV=1
Length=804
Score = 244 bits (623), Expect = 1e-66, Method: Composition-based stats.
Identities = 74/307 (24%), Positives = 123/307 (40%), Gaps = 17/307 (6%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
+ LG+G FG V G+ +AVK L + G Q +
Sbjct 477 FFEMNTIQTATNNFSLSNKLGQGGFGSVYKGKLQ-----DGKEIAVKQLSSSSG-QGKEE 530
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ 999
+ EI ++ L H ++++ GCC + EK L+ E++ SL ++ + + +
Sbjct 531 FMNEIVLISKLQHRNLVRVLGCCIEGEEK--LLIYEFMLNKSLDTFVFDARKKLEVDWPK 588
Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
Q I G+ YLH IHRDL N+LLD KI DFGLA+ + EG +
Sbjct 589 RFDIVQGIARGLLYLHRDSRLKVIHRDLKVSNILLDEKMNPKISDFGLAR-MYEGTQCQD 647
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIA 1115
+ + +PE F SD++SFGV L E++ S S + L+ A
Sbjct 648 KTRRVVGTLGYMSPEYAWTGVFSEKSDIYSFGVLLLEIIIGEKISRFSYGEEGKTLLAYA 707
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+ +LL++ + C + + + RP L+ +L T +
Sbjct 708 WESWGETKGIDLLDQDLADSCRPLEVGRCVQIGLLCVQHQPADRPNTLELLAMLTTTSDL 767
Query 1176 YQGQAPS 1182
+ P+
Sbjct 768 PSPKQPT 774
Score = 229 bits (585), Expect = 1e-61, Method: Composition-based stats.
Identities = 53/247 (21%), Positives = 94/247 (38%), Gaps = 45/247 (18%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L +++ + + + LGQG +VY+G+L+
Sbjct 475 LEFFEMNTIQTATNNFSLSNKLGQGGFGSVYKGKLQDGK--------------------- 513
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ +K L S F L+S++ H +L V G C+ G E +++ E++ +
Sbjct 514 ----EIAVKQLSSSSGQGKEEFMNEIVLISKLQHRNLVRVLGCCIEGEEKLLIYEFMLNK 569
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748
LD ++ R + + W + + Q +A L YL ++H ++ NILL
Sbjct 570 SLDTFVFDARKKLEVDWPKRFDIVQGIARGLLYLHRDSRLKVIHRDLKVSNILLDEK--- 626
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
K+SD G+ V + +++PE G S D + FG
Sbjct 627 ----MNPKISDFGLARMYEGTQCQDKTRRVVGTLGYMSPEYAWTGV--FSEKSDIYSFGV 680
Query 803 TLLEICF 809
LLEI
Sbjct 681 LLLEIII 687
>sp|Q9SGY7|PEK11_ARATH Putative proline-rich receptor-like protein
kinase PERK11 OS=Arabidopsis thaliana OX=3702 GN=PERK11
PE=2 SV=2
Length=718
Score = 243 bits (619), Expect = 1e-66, Method: Composition-based stats.
Identities = 73/299 (24%), Positives = 127/299 (42%), Gaps = 21/299 (7%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
+ K +GEG FG V G+ VA+K LK+ +R
Sbjct 357 HFTYEELSQITEGFCKSFVVGEGGFGCVYKGIL-----FEGKPVAIKQLKSVSAEGYRE- 410
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQL 1000
+K E++I+ ++H H++ G C + + L+ E+VP +L +L ++ ++
Sbjct 411 FKAEVEIISRVHHRHLVSLVGYCISEQHR--FLIYEFVPNNTLDYHLHGKNLPVLEWSRR 468
Query 1001 LLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ A +G+AYLH IHRD+ + N+LLD++ ++ DFGLA+ +
Sbjct 469 VRIAIGAAKGLAYLHEDCHPKIIHRDIKSSNILLDDEFEAQVADFGLARLNDTAQSHIST 528
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQ 1116
R + APE K SDV+SFGV L EL+T S P L+ A+
Sbjct 529 R--VMGTFGYLAPEYASSGKLTDRSDVFSFGVVLLELITGRKPVDTSQPLGEESLVEWAR 586
Query 1117 GQMTVL----RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
++ ++E+++ + ++ +C A RP ++ L T
Sbjct 587 PRLIEAIEKGDISEVVDPRLENDYVESEVYKMIETAASCVRHSALKRPRMVQVVRALDT 645
Score = 215 bits (548), Expect = 2e-57, Method: Composition-based stats.
Identities = 59/306 (19%), Positives = 112/306 (37%), Gaps = 51/306 (17%)
Query 546 SLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSH-------LGQG 598
+ +T++L + R +P + + H +E++Q++ +G+G
Sbjct 321 NGNSSAQNSSPDTNSLGNPKHGRGTPDSAVIGTSKIH-FTYEELSQITEGFCKSFVVGEG 379
Query 599 TRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYET 658
VY+G L V +K L + F
Sbjct 380 GFGCVYKGILFEGKP-------------------------VAIKQLKSVSAEGYREFKAE 414
Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQ 717
++S+V H HL + G C+ ++ E+V + LD L + + + ++ +A
Sbjct 415 VEIISRVHHRHLVSLVGYCISEQHRFLIYEFVPNNTLDYHLHGKNLPVLEWSRRVRIAIG 474
Query 718 LASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-- 772
A L+YL ++H ++ NILL A+ ++D G+ + +
Sbjct 475 AAKGLAYLHEDCHPKIIHRDIKSSNILLDDEFEAQ-------VADFGLARLNDTAQSHIS 527
Query 773 ---VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
+ +LAPE G L+ D + FG LLE+ + S+ E+
Sbjct 528 TRVMGTFGYLAPEYASSG--KLTDRSDVFSFGVVLLELITGRKPVDTSQPLGEESLVEWA 585
Query 830 QHRLPE 835
+ RL E
Sbjct 586 RPRLIE 591
>sp|Q3E9X6|CRK21_ARATH Cysteine-rich receptor-like protein kinase
21 OS=Arabidopsis thaliana OX=3702 GN=CRK21 PE=2 SV=1
Length=690
Score = 242 bits (617), Expect = 2e-66, Method: Composition-based stats.
Identities = 75/298 (25%), Positives = 109/298 (37%), Gaps = 18/298 (6%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
K LG G FG V + G VA K L Q +K E+ ++ L
Sbjct 362 NFHKSNKLGHGGFGAVYKGMF-----PNGTEVAAKRLSK-PSDQGEPEFKNEVLLVARLQ 415
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGM 1011
H++++ G + EK LV E+VP SL +L R + + + I G+
Sbjct 416 HKNLVGLLGFSVEGEEK--ILVYEFVPNKSLDHFLFDPIKRVQLDWPRRHNIIEGITRGI 473
Query 1012 AYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
YLH IHRDL A N+LLD + KI DFGLA+ +
Sbjct 474 LYLHQDSRLTIIHRDLKASNILLDAEMNPKIADFGLARNFRVNQTEANT-GRVVGTFGYM 532
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLTE 1126
PE + +F SDV+SFGV + E++ S L+ L E
Sbjct 533 PPEYVANGQFSTKSDVYSFGVLILEIIGGKKNSSFHQIDGSVSNLVTHVWRLRNNGSLLE 592
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
L++ H+ C + RP+ + +L V P F
Sbjct 593 LVDPAIGENYDKDEVIRCIHIGLLCVQENPDDRPSMSTIFRMLTNVSITLPVPQPPGF 650
Score = 218 bits (555), Expect = 2e-58, Method: Composition-based stats.
Identities = 68/385 (18%), Positives = 117/385 (30%), Gaps = 64/385 (17%)
Query 536 CLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHL 595
+ + FS+ R +P T++ + + + + L
Sbjct 311 QSFASENGYFSVSRR-PRRPYGTASPDDATDDLTASSGSLRFDFRAIKAATSNFHKSNKL 369
Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655
G G VY+G V K L F
Sbjct 370 GHGGFGAVYKGM-------------------------FPNGTEVAAKRLSKPSDQGEPEF 404
Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMV 713
L++++ H +L + G V G E I+V E+V + LD +L V + W +
Sbjct 405 KNEVLLVARLQHKNLVGLLGFSVEGEEKILVYEFVPNKSLDHFLFDPIKRVQLDWPRRHN 464
Query 714 VAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ + + + YL + ++H ++ NILL K++D G+ +
Sbjct 465 IIEGITRGILYLHQDSRLTIIHRDLKASNILLD-------AEMNPKIADFGLARNFRVNQ 517
Query 771 E------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
V ++ PE + G ST D + FG +LEI + +
Sbjct 518 TEANTGRVVGTFGYMPPEYVANG--QFSTKSDVYSFGVLILEIIGGKKNSSFHQIDGSVS 575
Query 825 HFYQRQHRLPEPSC------PQLAT------------LTSQCLTYEPTQRPSFRTILRDL 866
+ RL P + + C+ P RPS TI R L
Sbjct 576 NLVTHVWRLRNNGSLLELVDPAIGENYDKDEVIRCIHIGLLCVQENPDDRPSMSTIFRML 635
Query 867 TRLQPHNLADVLTVNPDSPASDPTV 891
T + S+P
Sbjct 636 TNVSITLPVPQPPGFFFRERSEPNP 660
>sp|Q9LW83|CE101_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase CES101 OS=Arabidopsis thaliana OX=3702
GN=CES101 PE=2 SV=2
Length=850
Score = 245 bits (625), Expect = 2e-66, Method: Composition-based stats.
Identities = 77/285 (27%), Positives = 119/285 (42%), Gaps = 19/285 (7%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
Y LGEG FG V GE VA+K L G Q +K E ++ L
Sbjct 525 DYFSDANKLGEGGFGPVYKGRL-----IDGEEVAIKRLSLASG-QGLVEFKNEAMLIAKL 578
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL----RDYLPRHSIGLAQLLLFAQQICEG 1010
H +++K GCC ++ EK L+ EY+P SL D L + + + I +G
Sbjct 579 QHTNLVKLLGCCVEKDEK--MLIYEYMPNKSLDYFLFDPLRKIVLDWKLRFRIMEGIIQG 636
Query 1011 MAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH IHRD+ A N+LLD D KI DFG+A+ + +
Sbjct 637 LLYLHKYSRLKVIHRDIKAGNILLDEDMNPKISDFGMARIFGAQESKANTKRVA-GTFGY 695
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHC--DSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+PE +E F SDV+SFGV + E++ +S L LI R+
Sbjct 696 MSPEYFREGLFSAKSDVFSFGVLMLEIICGRKNNSFHHDSEGPLNLIVHVWNLFKENRVR 755
Query 1126 ELLERGERLPRPDK-CPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
E+++ + + C + A RP+ +++ ++
Sbjct 756 EVIDPSLGDSAVENPQVLRCVQVALLCVQQNADDRPSMLDVVSMI 800
Score = 228 bits (580), Expect = 1e-60, Method: Composition-based stats.
Identities = 58/325 (18%), Positives = 108/325 (33%), Gaps = 64/325 (20%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + + + LG+G VY+GRL
Sbjct 511 ELQIFSFESVAFATDYFSDANKLGEGGFGPVYKGRLIDGE-------------------- 550
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
V +K L + + F A L++++ HT+L + G CV E +++ EY+ +
Sbjct 551 -----EVAIKRLSLASGQGLVEFKNEAMLIAKLQHTNLVKLLGCCVEKDEKMLIYEYMPN 605
Query 693 GPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGL 747
LD +L + + W + + + + L YL ++H ++ NILL
Sbjct 606 KSLDYFLFDPLRKIVLDWKLRFRIMEGIIQGLLYLHKYSRLKVIHRDIKAGNILLDE--- 662
Query 748 AEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
K+SD G+ + + +++PE G S D + FG
Sbjct 663 ----DMNPKISDFGMARIFGAQESKANTKRVAGTFGYMSPEYFREGL--FSAKSDVFSFG 716
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY------QRQHRLPEPSCPQLAT------------ 843
+LEI + + +++R+ E P L
Sbjct 717 VLMLEIICGRKNNSFHHDSEGPLNLIVHVWNLFKENRVREVIDPSLGDSAVENPQVLRCV 776
Query 844 -LTSQCLTYEPTQRPSFRTILRDLT 867
+ C+ RPS ++ +
Sbjct 777 QVALLCVQQNADDRPSMLDVVSMIY 801
>sp|Q8S9L6|CRK29_ARATH Cysteine-rich receptor-like protein kinase
29 OS=Arabidopsis thaliana OX=3702 GN=CRK29 PE=2 SV=1
Length=679
Score = 241 bits (616), Expect = 2e-66, Method: Composition-based stats.
Identities = 75/286 (26%), Positives = 118/286 (41%), Gaps = 28/286 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+LG G FG V + G+ +AVK L + G Q + +K EI +L L H +++
Sbjct 361 NELGRGGFGSVYKGVFPQ-----GQEIAVKRLSGNSG-QGDNEFKNEILLLAKLQHRNLV 414
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016
+ G C E+ LV E++ SL ++ R + I G+ YLH
Sbjct 415 RLIGFCIQGEER--LLVYEFIKNASLDQFIFDTEKRQLLDWVVRYKMIGGIARGLLYLHE 472
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE-YYRVREDGDSPVFWYAPEC 1072
IHRDL A N+LLD + KI DFGLAK G +R + APE
Sbjct 473 DSRFRIIHRDLKASNILLDQEMNPKIADFGLAKLFDSGQTMTHRFTSRIAGTYGYMAPEY 532
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS---SQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
+F +DV+SFGV + E++T + + +L+ + +++
Sbjct 533 AMHGQFSVKTDVFSFGVLVIEIITGKRNNNGGSNGDEDAEDLLSWVWRSWREDTILSVID 592
Query 1130 R----GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
G R H+ C + A+ RPT + +L +
Sbjct 593 PSLTAGSRNEI-----LRCIHIGLLCVQESAATRPTMATVSLMLNS 633
Score = 227 bits (578), Expect = 2e-61, Method: Composition-based stats.
Identities = 46/260 (18%), Positives = 90/260 (35%), Gaps = 47/260 (18%)
Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
+ + + LG+G +VY+G Q
Sbjct 347 FETLKTATDNFSSENELGRGGFGSVYKGV-------------------------FPQGQE 381
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+ +K L + F L++++ H +L + G C++G E ++V E++++ LD +
Sbjct 382 IAVKRLSGNSGQGDNEFKNEILLLAKLQHRNLVRLIGFCIQGEERLLVYEFIKNASLDQF 441
Query 699 LRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSP 753
+ + W + + +A L YL ++H ++ NILL +
Sbjct 442 IFDTEKRQLLDWVVRYKMIGGIARGLLYLHEDSRFRIIHRDLKASNILLDQE-------M 494
Query 754 FIKLSDPGVGLGALSREERV--------ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
K++D G+ S + ++APE G S D + FG ++
Sbjct 495 NPKIADFGLAKLFDSGQTMTHRFTSRIAGTYGYMAPEYAMHG--QFSVKTDVFSFGVLVI 552
Query 806 EICFDGEAPLQSRSPSEKEH 825
EI + E
Sbjct 553 EIITGKRNNNGGSNGDEDAE 572
>sp|O64768|RAF24_ARATH RAF-like serine/threonine-protein kinase
24 OS=Arabidopsis thaliana OX=3702 GN=RAF24 PE=1 SV=1
Length=1257
Score = 249 bits (636), Expect = 2e-66, Method: Composition-based stats.
Identities = 80/298 (27%), Positives = 125/298 (42%), Gaps = 38/298 (13%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-----GPQHR--SGWKQEIDILRTL 954
+LG G FG V + T+ VA+K +K C Q R S + E +IL L
Sbjct 979 ELGSGTFGTVYHGKWRGTD------VAIKRIKRSCFIGRSSEQERLTSEFWHEAEILSKL 1032
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAY 1013
+H +++ + G +D +L V EY+ GSLR L + + L+ A GM Y
Sbjct 1033 HHPNVMAFYGVVKDGPGGTLATVTEYMVNGSLRHVLLSNRHLDRRKRLIIAMDAAFGMEY 1092
Query 1014 LHAQHYIHRDLAARNVLLD----NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
LH++ +H DL N+L++ + K+GDFGL+K V + W A
Sbjct 1093 LHSKSIVHFDLKCDNLLVNLKDPARPICKVGDFGLSKI----KRNTLVTGGVRGTLPWMA 1148
Query 1070 PECLKE--YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
PE L K DV+SFG+ L+E+LT + + + + +
Sbjct 1149 PELLSGSSSKVSEKVDVFSFGIVLWEILTGEEPYANMHYGAI--------------IGGI 1194
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
+ R P+ C E LM+ CW + RP F + L+T+ P +
Sbjct 1195 VNNTLRPTVPNYCDPEWRMLMEQCWAPDPFVRPAFPEIARRLRTMSSSAVHTKPHAVN 1252
Score = 237 bits (605), Expect = 1e-62, Method: Composition-based stats.
Identities = 74/323 (23%), Positives = 124/323 (38%), Gaps = 47/323 (15%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
S + ++ +L LG GT VY G+ R V
Sbjct 965 SLQVIKNDDLEELKELGSGTFGTVYHGKWRGTD--------------------------V 998
Query 640 VLKVLDPS--------HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEY 689
+K + S + F+ A ++S++ H ++ +GV GP + VTEY
Sbjct 999 AIKRIKRSCFIGRSSEQERLTSEFWHEAEILSKLHHPNVMAFYGVVKDGPGGTLATVTEY 1058
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
+ +G L L R H+ ++++A A + YL +K++VH ++ N+L+ L +
Sbjct 1059 MVNGSLRHVLLSNR-HLDRRKRLIIAMDAAFGMEYLHSKSIVHFDLKCDNLLV---NLKD 1114
Query 750 GTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
P K+ D G+ L +PW+APE L G ++ +S +D + FG L E
Sbjct 1115 PARPICKVGDFGLSKIKRNTLVTGGVRGTLPWMAPELLSGSSSKVSEKVDVFSFGIVLWE 1174
Query 807 ICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
I GE P + + +P P+ L QC +P RP+F I
Sbjct 1175 IL-TGEEPYANMHYGAIIGGIVNNTLRPTVPNYCDPEWRMLMEQCWAPDPFVRPAFPEIA 1233
Query 864 RDLTRLQPHNLADVLTVNPDSPA 886
R L + +
Sbjct 1234 RRLRTMSSSAVHTKPHAVNHQIH 1256
>sp|O49339|PTI12_ARATH PTI1-like tyrosine-protein kinase 2 OS=Arabidopsis
thaliana OX=3702 GN=PTI12 PE=1 SV=1
Length=366
Score = 232 bits (591), Expect = 2e-66, Method: Composition-based stats.
Identities = 69/286 (24%), Positives = 123/286 (43%), Gaps = 22/286 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG +G+V G+ VA+K L + + + ++ ++ L HE++I+
Sbjct 77 IGEGSYGRVYYATL-----NDGKAVALKKLDVAPEAETNTEFLNQVSMVSRLKHENLIQL 131
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------IGLAQLLLFAQQICEGMA 1012
G C D+ + L E+ +GSL D L + + A + G+
Sbjct 132 VGYCVDENLR--VLAYEFATMGSLHDILHGRKGVQGAQPGPTLDWLTRVKIAVEAARGLE 189
Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH + IHRD+ + NVLL D K+ DF L+ P+ ++A
Sbjct 190 YLHEKVQPPVIHRDIRSSNVLLFEDYQAKVADFNLSNQAPDNAARLH-STRVLGTFGYHA 248
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE + SDV+SFGV L ELLT + P L+ A +++ ++ + +
Sbjct 249 PEYAMTGQLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRLSEDKVKQCV 308
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ + P K ++ + C + E+ FRP ++ L+ + +
Sbjct 309 DPKLKGEYPPKSVAKLAAVAALCVQYESEFRPNMSIVVKALQPLLK 354
Score = 196 bits (497), Expect = 1e-53, Method: Composition-based stats.
Identities = 58/310 (19%), Positives = 101/310 (33%), Gaps = 54/310 (17%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVE 611
Q + ++ A+ + + LS V S +G+G+ VY L
Sbjct 34 QKNQKPQAVVKPEAQKEALPIEVPPLSVDEVKEKTDNFGSKSLIGEGSYGRVYYATLNDG 93
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHL 670
V LK LD + + F S++S++ H +L
Sbjct 94 K-------------------------AVALKKLDVAPEAETNTEFLNQVSMVSRLKHENL 128
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG--------HVPMAWKMVVAQQLASAL 722
+ G CV ++ E+ G L L +G + ++ +A + A L
Sbjct 129 IQLVGYCVDENLRVLAYEFATMGSLHDILHGRKGVQGAQPGPTLDWLTRVKIAVEAARGL 188
Query 723 SYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG------LGALSREERV 773
YL K ++H ++ N+LL A K++D + L +
Sbjct 189 EYLHEKVQPPVIHRDIRSSNVLLFEDYQA-------KVADFNLSNQAPDNAARLHSTRVL 241
Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833
+ APE G L+ D + FG LLE+ + + ++ RL
Sbjct 242 GTFGYHAPEYAMTG--QLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRL 299
Query 834 PEPSCPQLAT 843
E Q
Sbjct 300 SEDKVKQCVD 309
>sp|Q9ZP16|CRK11_ARATH Cysteine-rich receptor-like protein kinase
11 OS=Arabidopsis thaliana OX=3702 GN=CRK11 PE=2 SV=2
Length=667
Score = 241 bits (614), Expect = 2e-66, Method: Composition-based stats.
Identities = 70/282 (25%), Positives = 109/282 (39%), Gaps = 20/282 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LGEG FG V G VAVK L G Q ++ E ++ L H +++
Sbjct 354 NKLGEGGFGAVYKG-----KLSNGTDVAVKRLSKKSG-QGTREFRNEAVLVTKLQHRNLV 407
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH- 1015
+ G C ++ E+ L+ E+V SL +L + + + I G+ YLH
Sbjct 408 RLLGFCLEREEQ--ILIYEFVHNKSLDYFLFDPEKQSQLDWTRRYKIIGGIARGILYLHQ 465
Query 1016 --AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRDL A N+LLD D KI DFGLA + + +PE
Sbjct 466 DSRLKIIHRDLKASNILLDADMNPKIADFGLATIFGV-EQTQGNTNRIAGTYAYMSPEYA 524
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL----ELIGIAQGQMTVLRLTELLE 1129
++ SD++SFGV + E+++ +S L+ A EL++
Sbjct 525 MHGQYSMKSDIYSFGVLVLEIISGKKNSGVYQMDETSTAGNLVTYASRLWRNKSPLELVD 584
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
H+ C + RP +I +L +
Sbjct 585 PTFGRNYQSNEVTRCIHIALLCVQENPEDRPMLSTIILMLTS 626
Score = 230 bits (586), Expect = 1e-62, Method: Composition-based stats.
Identities = 72/435 (17%), Positives = 126/435 (29%), Gaps = 74/435 (17%)
Query 466 PEDGLYLIHWSTS---HPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRS 522
+ G ++ S Y + A + P QD + G S
Sbjct 228 QKRGGVVMRPSCFLRWDLYTYSNAFDNLTVASPPPEPPVTVPQPAGDQDNPTNNDSKGIS 287
Query 523 FPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFH 582
V + +L F L R + + S +
Sbjct 288 AGVVVAITVPTVIAILILLVLGFVLFRRRKSYQRTKTE----SESDISTTDSLVYDFKTI 343
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
+ + + LG+G VY+G+L V +K
Sbjct 344 EAATNKFSTSNKLGEGGFGAVYKGKLSNG-------------------------TDVAVK 378
Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
L F A L++++ H +L + G C+ E I++ E+V + LD +L
Sbjct 379 RLSKKSGQGTREFRNEAVLVTKLQHRNLVRLLGFCLEREEQILIYEFVHNKSLDYFLFDP 438
Query 703 RGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ W + + +A + YL ++H ++ NILL K+
Sbjct 439 EKQSQLDWTRRYKIIGGIARGILYLHQDSRLKIIHRDLKASNILLD-------ADMNPKI 491
Query 758 SDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
+D G+ + +++PE G S D + FG +LEI G
Sbjct 492 ADFGLATIFGVEQTQGNTNRIAGTYAYMSPEYAMHG--QYSMKSDIYSFGVLVLEIIS-G 548
Query 812 EAPLQSRSPSEKE---HFYQRQHRLPEPSCP------------------QLATLTSQCLT 850
+ E + RL P + + C+
Sbjct 549 KKNSGVYQMDETSTAGNLVTYASRLWRNKSPLELVDPTFGRNYQSNEVTRCIHIALLCVQ 608
Query 851 YEPTQRPSFRTILRD 865
P RP TI+
Sbjct 609 ENPEDRPMLSTIILM 623
>sp|Q9SY95|Y1155_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g61550 OS=Arabidopsis thaliana OX=3702
GN=At1g61550 PE=2 SV=1
Length=802
Score = 244 bits (622), Expect = 2e-66, Method: Composition-based stats.
Identities = 75/308 (24%), Positives = 122/308 (40%), Gaps = 17/308 (6%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
+ LG+G FG V G+ +AVK L + G Q +
Sbjct 475 YFFEMKTIEIATNNFSLVNKLGQGGFGPVYKGKLQ-----DGKEIAVKRLSSSSG-QGKE 528
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLA 998
+ EI ++ L H ++++ GCC + E+ LV E++ SL ++ R I
Sbjct 529 EFMNEILLISKLQHINLVRILGCCIEGEER--LLVYEFMVNKSLDTFIFDSRKRVEIDWP 586
Query 999 QLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ Q I G+ YLH IHRD+ N+LLD+ KI DFGLA+ + EG +Y
Sbjct 587 KRFSIIQGIARGLLYLHRDSRLRIIHRDVKVSNILLDDKMNPKISDFGLAR-MYEGTKYQ 645
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL-ELIGI 1114
+ + +PE F SD +SFGV L E+++ S+ K L+
Sbjct 646 DNTRRIVGTLGYMSPEYAWTGVFSEKSDTYSFGVLLLEVISGEKISRFSYDKERKNLLAY 705
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
A L++ + C + + + RP L+ +L T +
Sbjct 706 AWESWCENGGVGFLDKDATDSCHPSEVGRCVQIGLLCVQHQPADRPNTLELLSMLTTTSD 765
Query 1175 KYQGQAPS 1182
+ P+
Sbjct 766 LPLPKEPT 773
Score = 233 bits (593), Expect = 1e-62, Method: Composition-based stats.
Identities = 54/254 (21%), Positives = 95/254 (37%), Gaps = 45/254 (18%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
L ++ + + ++ LGQG VY+G+L+
Sbjct 467 KSEDVSGLYFFEMKTIEIATNNFSLVNKLGQGGFGPVYKGKLQDGK-------------- 512
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+ +K L S F L+S++ H +L + G C+ G E ++V
Sbjct 513 -----------EIAVKRLSSSSGQGKEEFMNEILLISKLQHINLVRILGCCIEGEERLLV 561
Query 687 TEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNIL 741
E++ + LD ++ R V + W + + Q +A L YL ++H +V NIL
Sbjct 562 YEFMVNKSLDTFIFDSRKRVEIDWPKRFSIIQGIARGLLYLHRDSRLRIIHRDVKVSNIL 621
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAM 795
L K+SD G+ + + V + +++PE G S
Sbjct 622 LDDK-------MNPKISDFGLARMYEGTKYQDNTRRIVGTLGYMSPEYAWTGV--FSEKS 672
Query 796 DKWGFGATLLEICF 809
D + FG LLE+
Sbjct 673 DTYSFGVLLLEVIS 686
>sp|G5EGK5|CAM1_CAEEL Tyrosine-protein kinase receptor cam-1 OS=Caenorhabditis
elegans OX=6239 GN=cam-1 PE=1 SV=1
Length=928
Score = 246 bits (627), Expect = 2e-66, Method: Composition-based stats.
Identities = 94/319 (29%), Positives = 135/319 (42%), Gaps = 29/319 (9%)
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPTNDGT 923
+ + D + L +GEG FG V Y
Sbjct 558 PMDQHLQQARRFPSQEPIDDNSYKVFEITPSQLSVREKIGEGQFGVVHSGIYTSGLFAPE 617
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
VAVK + D R+ +QEI + T H ++IK G C + SL V EY+
Sbjct 618 PMAVAVKKCRHDATNAERAQLEQEIRAVATFDHPNVIKLIGVCY--MDNSLLAVFEYMVH 675
Query 984 GSLRDYLP------RHSIG-----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032
G L + L H +G A+ L A QI GM YL + ++HRDLA RN L+
Sbjct 676 GDLHELLKVRVPPADHDMGGITEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLVG 735
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
+ R +KI DFGL + G +YY++ PV W + E +++ +F ASDVWSFGVTL+
Sbjct 736 DTRTIKIADFGLMRT-SYGSDYYKMLHRSWMPVRWMSKEAIEQGRFSEASDVWSFGVTLW 794
Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152
E+ + + ++ EL+ L P CP +Y LM CW
Sbjct 795 EIWSFGRQ--------------PYEGASNQQVIELVANRHLLECPHNCPTNIYSLMVECW 840
Query 1153 ETEASFRPTFENLIPILKT 1171
RPTF + L++
Sbjct 841 HENIERRPTFSEIRSRLQS 859
Score = 224 bits (571), Expect = 3e-59, Method: Composition-based stats.
Identities = 73/374 (20%), Positives = 133/374 (36%), Gaps = 56/374 (15%)
Query 510 QDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARA 569
+ A+ + G S P + + ++ L P P + ++ AR
Sbjct 517 ANSAYYRKLNGTSTPIMGRVPPHVEMTSLLPSAQHLGP----PPYPMDQH----LQQARR 568
Query 570 SPRTLNLSQLSFH--RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
P + S+ + +++ +G+G V+ G
Sbjct 569 FPSQEPIDDNSYKVFEITPSQLSVREKIGEGQFGVVHSGI-------------------Y 609
Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYE-TASLMSQVSHTHLAFVHGVCVRGPENIMV 686
G + + V +K + A E ++ H ++ + GVC + V
Sbjct 610 TSGLFAPEPMAVAVKKCRHDATNAERAQLEQEIRAVATFDHPNVIKLIGVCYMDNSLLAV 669
Query 687 TEYVEHGPLDVWLR-------RERGHVPMAWK--MVVAQQLASALSYLENKNLVHGNVCG 737
EY+ HG L L+ + G + A + +A Q+A + YL + + VH ++
Sbjct 670 FEYMVHGDLHELLKVRVPPADHDMGGITEANAEFLYIATQIALGMEYLASMSFVHRDLAT 729
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV------ERIPWLAPECLPGGANSL 791
RN L+ G + IK++D G+ + + + W++ E + G
Sbjct 730 RNCLV-------GDTRTIKIADFGLMRTSYGSDYYKMLHRSWMPVRWMSKEAIEQG--RF 780
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCL 849
S A D W FG TL EI G P + S + +H L P + +L +C
Sbjct 781 SEASDVWSFGVTLWEIWSFGRQPYEGASNQQVIELVANRHLLECPHNCPTNIYSLMVECW 840
Query 850 TYEPTQRPSFRTIL 863
+RP+F I
Sbjct 841 HENIERRPTFSEIR 854
>sp|Q9I7F7|ACKL_DROME Activated Cdc42 kinase-like OS=Drosophila
melanogaster OX=7227 GN=Ack-like PE=1 SV=3
Length=1337
Score = 249 bits (636), Expect = 2e-66, Method: Composition-based stats.
Identities = 94/300 (31%), Positives = 146/300 (49%), Gaps = 27/300 (9%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
++ + + + LG G FG V + N+ VA+K L + + +
Sbjct 122 PNNKHIIPADSISVNKQLGTGEFGIVQQGVWSNGNER--IQVAIKCLCRERMQSNPMEFL 179
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-----GLAQL 1000
+E I+ ++ HE+I++ G SL LV E L SL + L + + L
Sbjct 180 KEAAIMHSIEHENIVRLYGVVLATD--SLMLVTELAHLRSLLECLKDSGLRVSFLTIPTL 237
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
FA QIC GM YL + IHRDLAARN+L+ + VKI DFGL++A+ G +YY+ +
Sbjct 238 CEFALQICNGMRYLEQKRLIHRDLAARNILVFSKDKVKISDFGLSRALGVGKDYYKTNFN 297
Query 1061 G--DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
P+ W APEC+ +F ASDVW+FGV L+E+ ++
Sbjct 298 VNLKLPIAWCAPECINYLRFTNASDVWAFGVCLWEMFSYGFQ--------------PWAA 343
Query 1119 MTVLRLTELLE--RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
+T L++ E ++ +RL +PD CP E Y LM CW+ +A+ RP F + L + +
Sbjct 344 LTGLQILEAIDAPNYQRLEQPDCCPSEYYTLMMKCWQDDAAKRPRFGEIYDQLPDMKPEQ 403
Score = 215 bits (548), Expect = 1e-55, Method: Composition-based stats.
Identities = 64/323 (20%), Positives = 116/323 (36%), Gaps = 48/323 (15%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
H + I+ LG G V +G + ++V +
Sbjct 126 HIIPADSISVNKQLGTGEFGIVQQGVWSNG----------------------NERIQVAI 163
Query 642 KVLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + F + A++M + H ++ ++GV + ++VTE L L+
Sbjct 164 KCLCRERMQSNPMEFLKEAAIMHSIEHENIVRLYGVVLATDSLMLVTELAHLRSLLECLK 223
Query 701 RER---GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ + A Q+ + + YLE K L+H ++ RNIL+ + +K+
Sbjct 224 DSGLRVSFLTIPTLCEFALQICNGMRYLEQKRLIHRDLAARNILV-------FSKDKVKI 276
Query 758 SDPGVGLGALSREERVER---------IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
SD G+ ++ + I W APEC+ + A D W FG L E+
Sbjct 277 SDFGLSRALGVGKDYYKTNFNVNLKLPIAWCAPECI--NYLRFTNASDVWAFGVCLWEMF 334
Query 809 FDGEAPLQSRSPSEKEHF----YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
G P + + + ++ P+ + TL +C + +RP F I
Sbjct 335 SYGFQPWAALTGLQILEAIDAPNYQRLEQPDCCPSEYYTLMMKCWQDDAAKRPRFGEIYD 394
Query 865 DLTRLQPHNLADVLTVNPDSPAS 887
L ++P L V+
Sbjct 395 QLPDMKPEQLKAVVNCTEPKKDH 417
>sp|P53668|LIMK1_MOUSE LIM domain kinase 1 OS=Mus musculus OX=10090
GN=Limk1 PE=1 SV=1
Length=647
Score = 240 bits (613), Expect = 2e-66, Method: Composition-based stats.
Identities = 75/309 (24%), Positives = 132/309 (43%), Gaps = 33/309 (11%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
+F L LG+G FG+ T+ TGE++ +K L + + +
Sbjct 328 CRPHRIFRPSDLIHGEVLGKGCFGQ----AIKVTHRETGEVMVMKEL-IRFDEETQRTFL 382
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLF 1003
+E+ ++R L H +++K+ G +K L + EY+ G+LR + +Q + F
Sbjct 383 KEVKVMRCLEHPNVLKFIGVLYK--DKRLNFITEYIKGGTLRGIIKNMDSQYPWSQRVSF 440
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY-------- 1055
A+ I GMAYLH+ + IHRDL + N L+ +R V + DFGLA+ + +
Sbjct 441 AKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLARLMIDEKNQSEDLRSLKK 500
Query 1056 ---RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
+ R +W APE + + DV+SFG+ L E++ ++ + ++
Sbjct 501 PDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFG 560
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+G + P CP + + C + + RP+F L L+T+
Sbjct 561 LNVRGFLDRY-------------CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETL 607
Query 1173 HEKYQGQAP 1181
G P
Sbjct 608 RMHLSGHLP 616
Score = 209 bits (531), Expect = 1e-55, Method: Composition-based stats.
Identities = 67/350 (19%), Positives = 123/350 (35%), Gaps = 57/350 (16%)
Query 547 LRRCCLPQPGETSNLII---MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603
LR C + TS+L R +L + ++ LG+G
Sbjct 294 LRSCSIDTSPGTSSLASPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQA 353
Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663
+ R G +V+K L + F + +M
Sbjct 354 IKVTHRETGE------------------------VMVMKELIRFDEETQRTFLKEVKVMR 389
Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723
+ H ++ GV + +TEY++ G L ++ P + ++ A+ +AS ++
Sbjct 390 CLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKNMDSQYPWSQRVSFAKDIASGMA 449
Query 724 YLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------------------G 765
YL + N++H ++ N L+ + + ++D G+
Sbjct 450 YLHSMNIIHRDLNSHNCLVRE-------NRNVVVADFGLARLMIDEKNQSEDLRSLKKPD 502
Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--FDGEAPLQSRSPSEK 823
R V W+APE + G S +D + FG L EI + + R+
Sbjct 503 RKKRYTVVGNPYWMAPEMING--RSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFG 560
Query 824 EHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
+ R P+CP +T +C +P +RPSF + + L L+ H
Sbjct 561 LNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETLRMH 610
>sp|Q54RR9|Y9844_DICDI Probable serine/threonine-protein kinase
DDB_G0282963 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0282963
PE=3 SV=1
Length=1761
Score = 250 bits (638), Expect = 2e-66, Method: Composition-based stats.
Identities = 71/281 (25%), Positives = 130/281 (46%), Gaps = 24/281 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G F KV Y GE+VA+K LK + + +K+E DIL + +++IK
Sbjct 1481 KIGAGSFSKVYKAKYM------GEIVAIKVLKGEATSEQIELFKKEYDILSLVSSQNLIK 1534
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH- 1018
+ G C+ EK L++V EY GSL + + I + + Q +G+ LH
Sbjct 1535 FYGACK---EKKLRMVTEYCQHGSLYHIMSKRKMDISWPLVFKWMHQAVDGINSLHTMRP 1591
Query 1019 -YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRD+ ++N+L+++ +K+ DFGLAK + + APE
Sbjct 1592 ALVHRDIKSQNLLINSQFDLKVADFGLAK---PTELQTGSNSTIKGTMAYCAPELYNGIS 1648
Query 1078 FYYASDVWSFGVTLYELLTHC--DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ +DV+S G+ L+E+ T Q P E+ + ++G R
Sbjct 1649 YSEKADVYSLGIVLWEITTRVITGKYQRPYEDNTEI------SFDFQIVIMSSKQGIRPT 1702
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
P P ++ +L++ CW + + RP+ + ++ + ++++ Y
Sbjct 1703 MPPNVPPKLSYLIQKCWNQDPNERPSCQQILLAITSLYDDY 1743
Score = 191 bits (484), Expect = 9e-48, Method: Composition-based stats.
Identities = 64/318 (20%), Positives = 114/318 (36%), Gaps = 55/318 (17%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ ++ + +G G+ + VY+ + E V +KV
Sbjct 1471 ISSTDLFLIKKIGAGSFSKVYKAKYMGE--------------------------IVAIKV 1504
Query 644 LDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
L + F + ++S VS +L +G C MVTEY +HG L + +
Sbjct 1505 LKGEATSEQIELFKKEYDILSLVSSQNLIKFYGACKEKKLR-MVTEYCQHGSLYHIMSKR 1563
Query 703 RGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ + Q ++ L LVH ++ +N+L+ + +K++D
Sbjct 1564 KMDISWPLVFKWMHQAVDGINSLHTMRPALVHRDIKSQNLLIN-------SQFDLKVADF 1616
Query 761 GVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF---DGEA 813
G+ L S + + APE G S S D + G L EI G+
Sbjct 1617 GLAKPTELQTGSNSTIKGTMAYCAPELYNG--ISYSEKADVYSLGIVLWEITTRVITGKY 1674
Query 814 PLQSRSPSEKEHFYQ---------RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+E +Q + +P P+L+ L +C +P +RPS + IL
Sbjct 1675 QRPYEDNTEISFDFQIVIMSSKQGIRPTMPPNVPPKLSYLIQKCWNQDPNERPSCQQILL 1734
Query 865 DLTRLQPHNLADVLTVNP 882
+T L + + N
Sbjct 1735 AITSLYDDYIYNPSRYND 1752
>sp|Q8LKZ1|NORK_PEA Nodulation receptor kinase OS=Pisum sativum
OX=3888 GN=NORK PE=1 SV=1
Length=924
Score = 246 bits (627), Expect = 2e-66, Method: Composition-based stats.
Identities = 73/278 (26%), Positives = 127/278 (46%), Gaps = 18/278 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG FG V D G+ VAVK ++ Q + E+++L + HE+++
Sbjct 601 IGEGGFGSVYRGTLD-----DGQEVAVKV-RSATSTQGTREFDNELNLLSAIQHENLVPL 654
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHA- 1016
G C + ++ LV ++ GSL D L R + L A G+AYLH
Sbjct 655 LGYCNEYDQQ--ILVYPFMSNGSLLDRLYGEPAKRKILDWPTRLSIALGAARGLAYLHTF 712
Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+ IHRD+ + N+LLD+ K+ DFG +K P+ + Y V + + PE K
Sbjct 713 PGRSVIHRDVKSSNILLDHSMCAKVADFGFSKYAPQEGDSY-VSLEVRGTAGYLDPEYYK 771
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ SDV+SFGV L E+++ + P L+ A+ + ++ E+++ G +
Sbjct 772 TQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRVEWSLVEWAKPYIRASKVDEIVDPGIK 831
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ V + C E +++RP +++ L+
Sbjct 832 GGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELED 869
Score = 215 bits (547), Expect = 4e-56, Method: Composition-based stats.
Identities = 86/393 (22%), Positives = 134/393 (34%), Gaps = 101/393 (26%)
Query 500 LRLRKFPIEQQDGAFVLEGWG-RSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGET 558
R R I LEG+G +++P + +L + DD F
Sbjct 542 CRYRHKSI-------TLEGFGGKTYPMATNIIFSLP-----SKDDFF------------- 576
Query 559 SNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618
++ P TL +L+ + + +G+G +VY G L
Sbjct 577 -----IKSVSVKPFTLEYIELATEK-------YKTLIGEGGFGSVYRGTL---------- 614
Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678
D GQE V +KV + F +L+S + H +L + G C
Sbjct 615 -------------DDGQE--VAVKVRSATSTQGTREFDNELNLLSAIQHENLVPLLGYCN 659
Query 679 RGPENIMVTEYVEHGPLDVWLRRE---RGHVPMAWKMVVAQQLASALSYLEN---KNLVH 732
+ I+V ++ +G L L E R + ++ +A A L+YL ++++H
Sbjct 660 EYDQQILVYPFMSNGSLLDRLYGEPAKRKILDWPTRLSIALGAARGLAYLHTFPGRSVIH 719
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPG 786
+V NILL S K++D G + E +L PE
Sbjct 720 RDVKSSNILLDH-------SMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKT 772
Query 787 GANSLSTAMDKWGFGATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCP-- 839
LS D + FG LLEI E P S E Y R ++ E P
Sbjct 773 --QQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRVEWSLVEWAKPYIRASKVDEIVDPGI 830
Query 840 ----------QLATLTSQCLTYEPTQRPSFRTI 862
++ + QCL T RP I
Sbjct 831 KGGYHAEALWRVVEVALQCLEPYSTYRPCMVDI 863
>sp|Q0WNY5|WAKLN_ARATH Wall-associated receptor kinase-like 18
OS=Arabidopsis thaliana OX=3702 GN=WAKL18 PE=2 SV=1
Length=793
Score = 243 bits (621), Expect = 3e-66, Method: Composition-based stats.
Identities = 70/281 (25%), Positives = 118/281 (42%), Gaps = 22/281 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G G V G VAVK K + E+ IL + H H++K
Sbjct 459 LGHGGQGTVYKGML-----VDGRTVAVKKSKV-IDEDKLQEFINEVVILSQINHRHVVKL 512
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQICEGMAYLHAQ 1017
GCC + + LV E++ G+L ++ +++ L A I ++YLH+
Sbjct 513 LGCCLET--EVPMLVYEFIINGNLFKHIHEEESDDYTMLWGMRLRIAVDIAGALSYLHSS 570
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
HRD+ + N+LLD K+ DFG +++V ++ V + PE +
Sbjct 571 ASSPIYHRDIKSTNILLDEKYRAKVADFGTSRSVTIDQTHWTT--VISGTVGYVDPEYYQ 628
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG---QMTVLRLTELLERG 1131
++ SDV+SFGV L EL+T D E++ +A+ M RLT++++
Sbjct 629 SSQYTEKSDVYSFGVILAELITG-DKPVIMVQNTQEIVALAEHFRVAMKEKRLTDIIDAR 687
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
R + V + C ++ RP + L+ +
Sbjct 688 IRNDCKPEQVMAVAKVAMKCLSSKGKKRPNMREVFTELERI 728
Score = 221 bits (562), Expect = 1e-58, Method: Composition-based stats.
Identities = 67/341 (20%), Positives = 125/341 (37%), Gaps = 68/341 (20%)
Query 559 SNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618
L G R N +L + ++ LG G + VY+G L +
Sbjct 426 QELNTREGYVEKTRVFNSRELEK---ATENFSENRVLGHGGQGTVYKGMLVDGRT----- 477
Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678
V +K D F ++SQ++H H+ + G C+
Sbjct 478 --------------------VAVKKSKVIDEDKLQEFINEVVILSQINHRHVVKLLGCCL 517
Query 679 RGPENIMVTEYVEHGPLDVWLRRERG-HVPMAW--KMVVAQQLASALSYLE---NKNLVH 732
++V E++ +G L + E M W ++ +A +A ALSYL + + H
Sbjct 518 ETEVPMLVYEFIINGNLFKHIHEEESDDYTMLWGMRLRIAVDIAGALSYLHSSASSPIYH 577
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGG 787
++ NILL A K++D G + + ++ PE
Sbjct 578 RDIKSTNILLDEKYRA-------KVADFGTSRSVTIDQTHWTTVISGTVGYVDPEYYQ-- 628
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-----EHFY--QRQHRLPEPSC-- 838
++ + D + FG L E+ G+ P+ +++ EHF ++ RL +
Sbjct 629 SSQYTEKSDVYSFGVILAELI-TGDKPVIMVQNTQEIVALAEHFRVAMKEKRLTDIIDAR 687
Query 839 ----------PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+A + +CL+ + +RP+ R + +L R+
Sbjct 688 IRNDCKPEQVMAVAKVAMKCLSSKGKKRPNMREVFTELERI 728
>sp|P14616|INSRR_HUMAN Insulin receptor-related protein OS=Homo
sapiens OX=9606 GN=INSRR PE=1 SV=2
Length=1297
Score = 249 bits (635), Expect = 3e-66, Method: Composition-based stats.
Identities = 93/317 (29%), Positives = 149/317 (47%), Gaps = 32/317 (10%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT-GEMVAVKALK 933
D D + + IR+LG+G FG V G VA+K +
Sbjct 957 NPEYFSASDMYVPDEWEVPREQISIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVN 1016
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991
P+ + +E +++ H+++ G QG+ +L ++ME + G L+ +L
Sbjct 1017 ELASPRECIEFLKEASVMKAFKCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSHLRSL 1074
Query 992 ----RHSIGLAQ-----LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
++ GL Q ++ A +I +GMAYL A ++HRDLAARN ++ D VKIGDF
Sbjct 1075 RPEAENNPGLPQPALGEMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDF 1134
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
G+ + V E +YYR G PV W APE LK+ F SDVWSFGV L+E++T
Sbjct 1135 GMTRDVYE-TDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVT------ 1187
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
L ++ ++ + + G L + CP ++ LM CW+ RP+F
Sbjct 1188 --------LAEQPYQGLSNEQVLKFVMDGGVLEELEGCPLQLQELMSRCWQPNPRLRPSF 1239
Query 1163 ENLIPILKTVHEKYQGQ 1179
++ L ++ E+ +
Sbjct 1240 THI---LDSIQEELRPS 1253
Score = 241 bits (616), Expect = 7e-64, Method: Composition-based stats.
Identities = 79/329 (24%), Positives = 129/329 (39%), Gaps = 51/329 (16%)
Query 555 PGETSNLIIMRGARASPRTLNLSQL---SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
G+ N + A +P + S + V +++I+ + LGQG+ VYEG R
Sbjct 944 YGKKRNRTLY--ASVNPEYFSASDMYVPDEWEVPREQISIIRELGQGSFGMVYEGLARGL 1001
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHL 670
+G+ + V LK ++ + + F + AS+M H+
Sbjct 1002 EAGE-------------------ESTPVALKTVNELASPRECIEFLKEASVMKAFKCHHV 1042
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP---------MAWKMVVAQQLASA 721
+ GV +G +++ E + G L LR R + + +A ++A
Sbjct 1043 VRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALGEMIQMAGEIADG 1102
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------ 775
++YL VH ++ RN ++++ +K+ D G+ + +
Sbjct 1103 MAYLAANKFVHRDLAARNCMVSQ-------DFTVKIGDFGMTRDVYETDYYRKGGKGLLP 1155
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
+ W+APE L G +T D W FG L EI E P Q S + F L E
Sbjct 1156 VRWMAPESLKDGI--FTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEE 1213
Query 836 -PSCP-QLATLTSQCLTYEPTQRPSFRTI 862
CP QL L S+C P RPSF I
Sbjct 1214 LEGCPLQLQELMSRCWQPNPRLRPSFTHI 1242
>sp|F1QVU0|LTK_DANRE Tyrosine-protein kinase receptor OS=Danio
rerio OX=7955 GN=ltk PE=1 SV=1
Length=1530
Score = 249 bits (637), Expect = 3e-66, Method: Composition-based stats.
Identities = 73/326 (22%), Positives = 116/326 (36%), Gaps = 40/326 (12%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S V +K IT L LG G VYEG++
Sbjct 923 SLSELKEVPRKNITLLRALGHGAFGEVYEGQVLGMN-------------------GENTA 963
Query 637 LRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
++V +K L + F A +MS+ SH ++ GV ++ ++ E + G +
Sbjct 964 MQVAIKTLPEICSEQDEMDFLMEALIMSKFSHQNIVRCIGVSLQILPRFILLELMTGGDM 1023
Query 696 DVWLRRERGHVP------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
+LR R M + +A+ +A YLE + +H ++ RN LL
Sbjct 1024 KSFLRLNRPRTNHSSSLSMLELLHMARDIALGCRYLEENHFIHRDIAARNCLLT----CP 1079
Query 750 GTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGAT 803
G K+ D G+ + + W+ PE G + D W FG
Sbjct 1080 GPDRVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPPEAFLEGI--FTCKTDTWSFGVL 1137
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRT 861
L EI G P ++ E F R+ P SCP + + +QC + P RP+F T
Sbjct 1138 LWEIFSLGYMPYPCKTNQEVLEFVTGGGRMDPPKSCPGPVYRIMTQCWQHCPEHRPNFTT 1197
Query 862 ILRDLTRLQPHNLADVLTVNPDSPAS 887
IL + + +
Sbjct 1198 ILERINYCTQDPDVINTPLPVECGPP 1223
Score = 248 bits (633), Expect = 8e-66, Method: Composition-based stats.
Identities = 93/344 (27%), Positives = 145/344 (42%), Gaps = 34/344 (10%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
Q P ++ + + + + S+ ++ + +R LG G FG+V
Sbjct 893 QSPEYKLSKIRSSTIMTDYNPNYGYFGKAASLSELKEVPRKNITLLRALGHGAFGEVYEG 952
Query 915 CYDPTN-DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
N + T VA+K L C Q + E I+ H++I++ G +
Sbjct 953 QVLGMNGENTAMQVAIKTLPEICSEQDEMDFLMEALIMSKFSHQNIVRCIGVSLQILPRF 1012
Query 974 LQLVMEYVPLGSLRDYLPRHS--------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
+ L E + G ++ +L + + + +LL A+ I G YL H+IHRD+A
Sbjct 1013 ILL--ELMTGGDMKSFLRLNRPRTNHSSSLSMLELLHMARDIALGCRYLEENHFIHRDIA 1070
Query 1026 ARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082
ARN LL DR+ KIGDFG+A+ + YYR PV W PE E F +
Sbjct 1071 ARNCLLTCPGPDRVAKIGDFGMARDIYRA-SYYRKGGRAMLPVKWMPPEAFLEGIFTCKT 1129
Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
D WSFGV L+E+ + L + T + E + G R+ P CP
Sbjct 1130 DTWSFGVLLWEIFS--------------LGYMPYPCKTNQEVLEFVTGGGRMDPPKSCPG 1175
Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
VY +M CW+ RP F + L+ ++ Y Q P V +
Sbjct 1176 PVYRIMTQCWQHCPEHRPNFTTI---LERIN--YCTQDPDVINT 1214
>sp|C0LGL9|FEI2_ARATH LRR receptor-like serine/threonine-protein
kinase FEI 2 OS=Arabidopsis thaliana OX=3702 GN=FEI2 PE=1
SV=1
Length=589
Score = 238 bits (608), Expect = 3e-66, Method: Composition-based stats.
Identities = 67/313 (21%), Positives = 134/313 (43%), Gaps = 20/313 (6%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ AS + L + +G G FG V + G + A+K +
Sbjct 285 MFHGDLPYASKDIIKKLESLNEEHIIGCGGFGTVYK-----LSMDDGNVFALKRI-VKLN 338
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995
+++E++IL ++ H +++ +G C K L+ +Y+P GSL + L + +
Sbjct 339 EGFDRFFERELEILGSIKHRYLVNLRGYCNSPTSK--LLLYDYLPGGSLDEALHKRGEQL 396
Query 996 GLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
+ +G+AYLH + IHRD+ + N+LLD + ++ DFGLAK + +
Sbjct 397 DWDSRVNIIIGAAKGLAYLHHDCSPRIIHRDIKSSNILLDGNLEARVSDFGLAKLLEDEE 456
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP-TKFLEL 1111
+ + + APE ++ + +DV+SFGV + E+L+ + + K +
Sbjct 457 SH--ITTIVAGTFGYLAPEYMQSGRATEKTDVYSFGVLVLEVLSGKLPTDASFIEKGFNI 514
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+G ++ R E+++ + + + C + RPT ++ +L++
Sbjct 515 VGWLNFLISENRAKEIVDLSCEG-VERESLDALLSIATKCVSSSPDERPTMHRVVQLLES 573
Query 1172 VHEKYQGQAPSVF 1184
+ PS F
Sbjct 574 ---EVMTPCPSDF 583
Score = 194 bits (492), Expect = 5e-51, Method: Composition-based stats.
Identities = 65/374 (17%), Positives = 127/374 (34%), Gaps = 64/374 (17%)
Query 535 GCLLRAGDDCFSLRRCCLPQPG-ETSNLIIMRGARASPRTLN--LSQLSFHRVDQ-KEIT 590
G LL CF E+ +L+I G AS + L S + + + +
Sbjct 246 GGLLLVALMCFWGCFLYKKLGRVESKSLVIDVGGGASIVMFHGDLPYASKDIIKKLESLN 305
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ +G G VY+ MDD + LK + +
Sbjct 306 EEHIIGCGGFGTVYK-------------LSMDDGNVF------------ALKRIVKLNEG 340
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
F ++ + H +L + G C +++ +Y+ G LD L + +
Sbjct 341 FDRFFERELEILGSIKHRYLVNLRGYCNSPTSKLLLYDYLPGGSLDEALHKRGEQLDWDS 400
Query 711 KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
++ + A L+YL + ++H ++ NILL + ++SD G+
Sbjct 401 RVNIIIGAAKGLAYLHHDCSPRIIHRDIKSSNILLD-------GNLEARVSDFGLAKLLE 453
Query 768 SREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
E + +LAPE + G + D + FG +LE+ G+ P + +
Sbjct 454 DEESHITTIVAGTFGYLAPEYMQSGRA--TEKTDVYSFGVLVLEVLS-GKLPTDASFIEK 510
Query 823 KEHFYQRQHRL-----------------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ + L S L ++ ++C++ P +RP+ +++
Sbjct 511 GFNIVGWLNFLISENRAKEIVDLSCEGVERESLDALLSIATKCVSSSPDERPTMHRVVQL 570
Query 866 LTRLQPHNLADVLT 879
L
Sbjct 571 LESEVMTPCPSDFY 584
>sp|A7J1T0|M313B_XENLA Mitogen-activated protein kinase kinase
kinase 13-B OS=Xenopus laevis OX=8355 GN=map3k13-b PE=2 SV=1
Length=961
Score = 246 bits (627), Expect = 3e-66, Method: Composition-based stats.
Identities = 84/301 (28%), Positives = 126/301 (42%), Gaps = 35/301 (12%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ + + + D + +++ LG G G V L + GE VA+K
Sbjct 145 WNIIGKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFR------GEEVAIK 198
Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
+ R + +I LR L H +II +KG C ++MEY G L + L
Sbjct 199 KV--------REQKETDIKHLRKLKHPNIIAFKGVCTQA--PCYCILMEYCAQGQLYEVL 248
Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
+ L+ ++ I GM YLH IHRDL + NVL+ + VKI DFG +K +
Sbjct 249 RAGRKVTPKLLVEWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHADTVKISDFGTSKELS 308
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
+ + V W APE ++ D+WSFGV L+ELLT P K +
Sbjct 309 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVLLWELLTG-----EIPYKDV 359
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ I G + LP P CP LMK W+++ RP+F ++ L
Sbjct 360 DSSAIIWGVGSN---------SLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQILMHL 410
Query 1170 K 1170
Sbjct 411 D 411
Score = 218 bits (556), Expect = 4e-57, Method: Composition-based stats.
Identities = 78/390 (20%), Positives = 133/390 (34%), Gaps = 60/390 (15%)
Query 484 ILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDD 543
++ R Q + + LR + P G G + + ++ +G+
Sbjct 72 SISEDSRDQFENSVLQLRDQDEPENTAPQGSSHSGDGGNNSANEDIRIHFSRSRSGSGNG 131
Query 544 CFS--LRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRT 601
F L C P + +A L Q V +EI++L LG G +
Sbjct 132 GFLEGLFGCLRP--------VWNIIGKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQG 183
Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL 661
V+ G+ R E V +K +
Sbjct 184 AVFLGKFRGE--------------------------EVAIKKVREQKE-------TDIKH 210
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA 721
+ ++ H ++ GVC + P ++ EY G L LR R P + + +AS
Sbjct 211 LRKLKHPNIIAFKGVCTQAPCYCILMEYCAQGQLYEVLRAGRKVTP-KLLVEWSTGIASG 269
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV---ERIPW 778
++YL ++H ++ N+L+ + +K+SD G + ++ + W
Sbjct 270 MNYLHLHKIIHRDLKSPNVLVTH-------ADTVKISDFGTSKELSDKSTKMSFAGTVAW 322
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPE 835
+APE + +S +D W FG L E+ GE P + S +P
Sbjct 323 MAPEVIRN--EPVSEKVDIWSFGVLLWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPS 379
Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
L Q +P RPSFR IL
Sbjct 380 TCPDGFKILMKQTWQSKPRNRPSFRQILMH 409
>sp|C0LGL4|Y2289_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At2g28960 OS=Arabidopsis thaliana OX=3702
GN=At2g28960 PE=1 SV=1
Length=880
Score = 244 bits (624), Expect = 4e-66, Method: Composition-based stats.
Identities = 72/316 (23%), Positives = 129/316 (41%), Gaps = 17/316 (5%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
H L + ++ + + R LGEG FG V + T + +AVK
Sbjct 547 QHGLPNRPSIFTQTKRFTYSEVEALTDNFERVLGEGGFGVVYHGILNGT-----QPIAVK 601
Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
L + Q +K E+++L ++H +++ G C++ E +L L+ EY P G L+ +L
Sbjct 602 -LLSQSSVQGYKEFKAEVELLLRVHHVNLVSLVGYCDE--ESNLALLYEYAPNGDLKQHL 658
Query 991 PRH----SIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
+ + L + +G+ YLH +HRD+ N+LLD K+ DFG
Sbjct 659 SGERGGSPLKWSSRLKIVVETAQGLEYLHTGCKPPMVHRDVKTTNILLDEHFQAKLADFG 718
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
L+++ P G E + +P + PE + + SDV+SFG+ L E++T Q
Sbjct 719 LSRSFPVGGETHVSTAVAGTP-GYLDPEYYRTNRLNEKSDVYSFGIVLLEIITSRPVIQQ 777
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163
K + +T + +++ + + +C + RPT
Sbjct 778 TREK-PHIAAWVGYMLTKGDIENVVDPRLNRDYEPTSVWKALEIAMSCVNPSSEKRPTMS 836
Query 1164 NLIPILKTVHEKYQGQ 1179
+ LK +
Sbjct 837 QVTNELKQCLTLENSK 852
Score = 212 bits (539), Expect = 3e-55, Method: Composition-based stats.
Identities = 71/347 (20%), Positives = 115/347 (33%), Gaps = 68/347 (20%)
Query 554 QPGETSNLIIMRGARASPRTL--NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
+P + +L ++ + ++ + ++ V+ LG+G VY G L
Sbjct 536 RPTQVDSLPTVQHGLPNRPSIFTQTKRFTYSEVEALTDNFERVLGEGGFGVVYHGILNGT 595
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
+ +K+L S F L+ +V H +L
Sbjct 596 QP-------------------------IAVKLLSQSSVQGYKEFKAEVELLLRVHHVNLV 630
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE--- 726
+ G C ++ EY +G L L ERG P+ W ++ + + A L YL
Sbjct 631 SLVGYCDEESNLALLYEYAPNGDLKQHLSGERGGSPLKWSSRLKIVVETAQGLEYLHTGC 690
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERV-----ERIPWLA 780
+VH +V NILL KL+D G+ + E V +L
Sbjct 691 KPPMVHRDVKTTNILLDE-------HFQAKLADFGLSRSFPVGGETHVSTAVAGTPGYLD 743
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR----------- 829
PE N L+ D + FG LLEI Q+R EK H
Sbjct 744 PEYYRT--NRLNEKSDVYSFGIVLLEIITSRPVIQQTR---EKPHIAAWVGYMLTKGDIE 798
Query 830 ---QHRLPEPSCPQLA----TLTSQCLTYEPTQRPSFRTILRDLTRL 869
RL P + C+ +RP+ + +L +
Sbjct 799 NVVDPRLNRDYEPTSVWKALEIAMSCVNPSSEKRPTMSQVTNELKQC 845
>sp|O59790|ARK1_SCHPO Serine/threonine-protein kinase ark1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=ark1 PE=1 SV=2
Length=355
Score = 231 bits (588), Expect = 4e-66, Method: Composition-based stats.
Identities = 68/283 (24%), Positives = 111/283 (39%), Gaps = 29/283 (10%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGW 944
FH + + LG+G FG+V L TG +VA+K L +
Sbjct 79 PQWREFHIGMFEIGKPLGKGKFGRVYL----AKEKKTGFIVALKTLHKSELVQSKIEKQV 134
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLF 1003
++EI+I L H++I++ G D EK + L++E+ G L +L R +
Sbjct 135 RREIEIQSNLRHKNILRLYGHFHD--EKRIYLILEFAGRGELYQHLRRAKRFSEEVASKY 192
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
Q+ ++YLH +H IHRD+ N+LL D +K+ DFG + P R
Sbjct 193 IFQMANALSYLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNR-----RTTLCG 247
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
+ + PE ++ + D+WS GV YE L + IA+
Sbjct 248 TLDYLPPEMVEGKEHTEKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVD----- 302
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L P P + L+ + R + E ++
Sbjct 303 ----------LKIPSFVPPDARDLISRLLQHNPEKRMSLEQVM 335
Score = 197 bits (502), Expect = 1e-54, Method: Composition-based stats.
Identities = 64/290 (22%), Positives = 102/290 (35%), Gaps = 42/290 (14%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS- 647
LG+G VY + + G V LK L S
Sbjct 89 FEIGKPLGKGKFGRVYLAKEKKTGF------------------------IVALKTLHKSE 124
Query 648 --HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
I + S + H ++ ++G ++ E+ G L LRR +
Sbjct 125 LVQSKIEKQVRREIEIQSNLRHKNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAK-R 183
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
Q+A+ALSYL K+++H ++ NILL G IKLSD G +
Sbjct 184 FSEEVASKYIFQMANALSYLHKKHVIHRDIKPENILL-------GIDGEIKLSDFGWSVH 236
Query 766 ALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
A S R + +L PE + G + +D W G E G P + S
Sbjct 237 APSNRRTTLCGTLDYLPPEMVEG--KEHTEKVDLWSLGVLTYEFLV-GAPPFEDMSGHSA 293
Query 824 --EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
+ + ++P P L S+ L + P +R S ++R ++
Sbjct 294 TYKRIAKVDLKIPSFVPPDARDLISRLLQHNPEKRMSLEQVMRHPWIVKY 343
>sp|O61125|STK4_DICDI Serine/threonine-protein kinase 4 homolog
A OS=Dictyostelium discoideum OX=44689 GN=krsA PE=1 SV=1
Length=461
Score = 234 bits (597), Expect = 4e-66, Method: Composition-based stats.
Identities = 67/292 (23%), Positives = 129/292 (44%), Gaps = 25/292 (9%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
++ + +++ + LGEG +G V Y N TG +VA+K + D
Sbjct 1 MSTLNVPKETMSRKDPEKFFTIVEKLGEGSYGSV----YKAINISTGIVVAIKKVSVD-- 54
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD--YLPRHSI 995
++EI ++ +I+ Y + E + +VME+ GS+ D + ++
Sbjct 55 -NDLEDMEKEISFMKQCKSPYIVTYYASFRKENE--VWIVMEHCGAGSVCDAMKITDKTL 111
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
Q+ + ++ + +G+AYLH+ IHRD+ A N+L+++ K+ DFG++ + +
Sbjct 112 SEDQIAVVSRDVLQGLAYLHSVRKIHRDIKAGNILMNHKGESKLADFGVSGQLSDTMA-- 169
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
R+ FW APE ++E + Y +D+WS+G+T E+ + PP +
Sbjct 170 -KRQTVIGTPFWMAPEVIQEIGYDYKADIWSYGITCIEM-----AESKPP------LFNV 217
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + +L P+K E + C + RP+ E L+
Sbjct 218 HPMRVIFMIPNPSRPPPKLTEPEKWSPEFNDFLAKCLTRKPELRPSAEELLK 269
Score = 191 bits (485), Expect = 3e-51, Method: Composition-based stats.
Identities = 60/307 (20%), Positives = 113/307 (37%), Gaps = 47/307 (15%)
Query 572 RTLNLSQLSFHRVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
TLN+ + + R D ++ T + LG+G+ +VY+ G
Sbjct 2 STLNVPKETMSRKDPEKFFTIVEKLGEGSYGSVYKAINISTG------------------ 43
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
+ V +K + + + + S M Q ++ + + E +V E+
Sbjct 44 ------IVVAIKKVSVDNDLEDME--KEISFMKQCKSPYIVTYYASFRKENEVWIVMEHC 95
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G + ++ + VV++ + L+YL + +H ++ NIL+ G +
Sbjct 96 GAGSVCDAMKITDKTLSEDQIAVVSRDVLQGLAYLHSVRKIHRDIKAGNILMNHKGES-- 153
Query 751 TSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
KL+D G + R+ + W+APE + D W +G T +E
Sbjct 154 -----KLADFGVSGQLSDTMAKRQTVIGTPFWMAPEVIQEIGYDY--KADIWSYGITCIE 206
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRL------PEPSCPQLATLTSQCLTYEPTQRPSFR 860
+ + PL + P R PE P+ ++CLT +P RPS
Sbjct 207 MAES-KPPLFNVHPMRVIFMIPNPSRPPPKLTEPEKWSPEFNDFLAKCLTRKPELRPSAE 265
Query 861 TILRDLT 867
+L+
Sbjct 266 ELLKHPF 272
>sp|Q94AG2|SERK1_ARATH Somatic embryogenesis receptor kinase 1
OS=Arabidopsis thaliana OX=3702 GN=SERK1 PE=1 SV=2
Length=625
Score = 239 bits (610), Expect = 4e-66, Method: Composition-based stats.
Identities = 69/279 (25%), Positives = 119/279 (43%), Gaps = 20/279 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FGKV G +VAVK LK + P ++ E++++ H ++++
Sbjct 308 LGRGGFGKVYKGRL-----ADGTLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRL 362
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ 1017
+G C E+ LV Y+ GS+ L + A G++YLH
Sbjct 363 RGFCMTPTER--LLVYPYMANGSVASCLRERPPSQPPLDWPTRKRIALGSARGLSYLHDH 420
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRD+ A N+LLD + +GDFGLAK + + V + APE L
Sbjct 421 CDPKIIHRDVKAANILLDEEFEAVVGDFGLAKLMDYKDTH--VTTAVRGTIGHIAPEYLS 478
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
K +DV+ +G+ L EL+T + + + L+ +G + +L L++
Sbjct 479 TGKSSEKTDVFGYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEMLVDPD 538
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ ++ +V + C + RP ++ +L+
Sbjct 539 LQTNYEERELEQVIQVALLCTQGSPMERPKMSEVVRMLE 577
Score = 196 bits (497), Expect = 2e-51, Method: Composition-based stats.
Identities = 69/324 (21%), Positives = 109/324 (34%), Gaps = 67/324 (21%)
Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + S V + + LG+G VY+GRL
Sbjct 286 QLKRFSLRELQVASDGFSNKNILGRGGFGKVYKGRLADG--------------------- 324
Query 633 RGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
V +K L L F ++S H +L + G C+ E ++V Y+
Sbjct 325 ----TLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMA 380
Query 692 HGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745
+G + LR R P+ W + +A A LSYL + ++H +V NILL
Sbjct 381 NGSVASCLRERPPSQPPLDWPTRKRIALGSARGLSYLHDHCDPKIIHRDVKAANILLDEE 440
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800
A + D G+ ++ V I +APE L G + S D +G+
Sbjct 441 FEAV-------VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 491
Query 801 GATLLEICFDGEAPLQSR--SPSEKEHFYQRQHRLPEPSCPQLAT--------------- 843
G LLE+ A +R + + + L E L
Sbjct 492 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEMLVDPDLQTNYEERELEQV 551
Query 844 --LTSQCLTYEPTQRPSFRTILRD 865
+ C P +RP ++R
Sbjct 552 IQVALLCTQGSPMERPKMSEVVRM 575
>sp|P43405|KSYK_HUMAN Tyrosine-protein kinase SYK OS=Homo sapiens
OX=9606 GN=SYK PE=1 SV=1
Length=635
Score = 239 bits (610), Expect = 4e-66, Method: Composition-based stats.
Identities = 101/325 (31%), Positives = 144/325 (44%), Gaps = 23/325 (7%)
Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY--LKKIRDLGEGHF 908
YEP P L V+ R + ++LG G+F
Sbjct 323 YEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNF 382
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
G V Y V + LK + P + E ++++ L + +I++ G CE
Sbjct 383 GTVKKGYYQMKKVVKTVAVKI--LKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICE 440
Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
+S LVME LG L YL ++ + ++ Q+ GM YL +++HRDLAA
Sbjct 441 ---AESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAA 497
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RNVLL KI DFGL+KA+ YY+ + G PV WYAPEC+ YKF SDVWS
Sbjct 498 RNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWS 557
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
FGV ++E ++ M +T +LE+GER+ P CP E+Y
Sbjct 558 FGVLMWEAFSYGQK--------------PYRGMKGSEVTAMLEKGERMGCPAGCPREMYD 603
Query 1147 LMKNCWETEASFRPTFENLIPILKT 1171
LM CW + RP F + L+
Sbjct 604 LMNLCWTYDVENRPGFAAVELRLRN 628
Score = 207 bits (528), Expect = 2e-55, Method: Composition-based stats.
Identities = 66/290 (23%), Positives = 114/290 (39%), Gaps = 40/290 (14%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ LG G V +G +++ K+ + P LK
Sbjct 373 EDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDP----------ALK-------- 414
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
A++M Q+ + ++ + G+C ++V E E GPL+ +L++ R HV
Sbjct 415 --DELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNR-HVKDKN 470
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ + Q++ + YLE N VH ++ RN+LL T + K+SD G+ + E
Sbjct 471 IIELVHQVSMGMKYLEESNFVHRDLAARNVLL-------VTQHYAKISDFGLSKALRADE 523
Query 771 ERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ + W APEC+ S+ D W FG + E G+ P + SE
Sbjct 524 NYYKAQTHGKWPVKWYAPECI--NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEV 581
Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
++ R+ P ++ L + C TY+ RP F + L
Sbjct 582 TAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYY 631
Score = 37.7 bits (86), Expect = 0.80, Method: Composition-based stats.
Identities = 19/101 (19%), Positives = 34/101 (34%), Gaps = 15/101 (15%)
Query 453 GPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQ 509
G + + L DGLYL+ S ++ L+VA +A + IE+
Sbjct 18 GNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKA---------HHYTIER 68
Query 510 QDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRC 550
+ GR+ S +L + L++
Sbjct 69 ELNGTYAIAGGRTHASPADL---CHYHSQESDGLVCLLKKP 106
>sp|P55245|EGFR_MACMU Epidermal growth factor receptor OS=Macaca
mulatta OX=9544 GN=EGFR PE=2 SV=2
Length=1210
Score = 248 bits (633), Expect = 4e-66, Method: Composition-based stats.
Identities = 91/272 (33%), Positives = 134/272 (49%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + VA+K L+ P+ E ++ ++ + H+ +
Sbjct 718 LGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRL 777
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C +QL+ + +P G L DY+ H IG LL + QI +GM YL + +
Sbjct 778 LGICLTST---VQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLV 834
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ + VKI DFGLAK + + Y E G P+ W A E + + +
Sbjct 835 HRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHA-EGGKVPIKWMALESILHRIYTH 893
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + ++ +LE+GERLP+P C
Sbjct 894 QSDVWSYGVTVWELMTFGSK--------------PYDGIPASEISSILEKGERLPQPPIC 939
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW +A RP F LI +
Sbjct 940 TIDVYMIMVKCWMIDADSRPKFRELIIEFSKM 971
Score = 222 bits (565), Expect = 8e-58, Method: Composition-based stats.
Identities = 67/337 (20%), Positives = 133/337 (39%), Gaps = 39/337 (12%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P +Q + + E ++ LG G VY+G EG
Sbjct 693 TPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKV-------------- 738
Query 630 GRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ V +K L + + A +M+ V + H+ + G+C+ ++T+
Sbjct 739 ------KIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQ-LITQ 791
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ G L ++R + ++ + + Q+A ++YLE++ LVH ++ RN+L+
Sbjct 792 LMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLV------ 845
Query 749 EGTSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGA 802
T +K++D G+ LGA +E E I W+A E + + D W +G
Sbjct 846 -KTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRI--YTHQSDVWSYGV 902
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860
T+ E+ G P SE ++ RLP+P + + +C + RP FR
Sbjct 903 TVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFR 962
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897
++ + +++ ++ + Y
Sbjct 963 ELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYR 999
>sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo
sapiens OX=9606 GN=EGFR PE=1 SV=2
Length=1210
Score = 248 bits (633), Expect = 4e-66, Method: Composition-based stats.
Identities = 91/272 (33%), Positives = 134/272 (49%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + VA+K L+ P+ E ++ ++ + H+ +
Sbjct 718 LGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRL 777
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C +QL+ + +P G L DY+ H IG LL + QI +GM YL + +
Sbjct 778 LGICLTST---VQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLV 834
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ + VKI DFGLAK + + Y E G P+ W A E + + +
Sbjct 835 HRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHA-EGGKVPIKWMALESILHRIYTH 893
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + ++ +LE+GERLP+P C
Sbjct 894 QSDVWSYGVTVWELMTFGSK--------------PYDGIPASEISSILEKGERLPQPPIC 939
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW +A RP F LI +
Sbjct 940 TIDVYMIMVKCWMIDADSRPKFRELIIEFSKM 971
Score = 222 bits (565), Expect = 8e-58, Method: Composition-based stats.
Identities = 67/337 (20%), Positives = 133/337 (39%), Gaps = 39/337 (12%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P +Q + + E ++ LG G VY+G EG
Sbjct 693 TPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKV-------------- 738
Query 630 GRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ V +K L + + A +M+ V + H+ + G+C+ ++T+
Sbjct 739 ------KIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQ-LITQ 791
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ G L ++R + ++ + + Q+A ++YLE++ LVH ++ RN+L+
Sbjct 792 LMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLV------ 845
Query 749 EGTSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGA 802
T +K++D G+ LGA +E E I W+A E + + D W +G
Sbjct 846 -KTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRI--YTHQSDVWSYGV 902
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860
T+ E+ G P SE ++ RLP+P + + +C + RP FR
Sbjct 903 TVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFR 962
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897
++ + +++ ++ + Y
Sbjct 963 ELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYR 999
>sp|Q9WTL4|INSRR_MOUSE Insulin receptor-related protein OS=Mus
musculus OX=10090 GN=Insrr PE=1 SV=2
Length=1300
Score = 248 bits (634), Expect = 4e-66, Method: Composition-based stats.
Identities = 95/329 (29%), Positives = 154/329 (47%), Gaps = 36/329 (11%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT-GEMVAV 929
++ D + + IR+LG+G FG V G VA+
Sbjct 953 YTSVNPEYFSASHMYVPDEWEVPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVAL 1012
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K + + R + +E +++ H+++ G QG+ +L ++ME + G L+ +
Sbjct 1013 KTVNELASARERVEFLKEASVMKAFKCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSH 1070
Query 990 LP------RHSIGLAQ-----LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
L ++ GL Q ++ A +I +GMAYL A+ ++HRDLAARN ++ D VK
Sbjct 1071 LRSLRPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQDFTVK 1130
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
IGDFG+ + V E +YYR G PV W APE LK+ F SDVWSFGV L+E++T
Sbjct 1131 IGDFGMTRDVYE-TDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVT-- 1187
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
L ++ ++ + + G L + CP ++ LM+ CW+
Sbjct 1188 ------------LAEQPYQGLSNEQVLKFVMDGGVLEELENCPIQLQELMRLCWQHSPRL 1235
Query 1159 RPTFENLIPILKTVHEKYQGQAPSVFSVC 1187
RPTF + IL + ++ + F +C
Sbjct 1236 RPTF---VHILDRIQDELRPS----FRLC 1257
Score = 240 bits (612), Expect = 2e-63, Method: Composition-based stats.
Identities = 74/324 (23%), Positives = 123/324 (38%), Gaps = 46/324 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
V +++I + LGQG+ VYEG R +G+ + V L
Sbjct 972 WEVPREQIAIIRELGQGSFGMVYEGLARGLEAGE-------------------ESTPVAL 1012
Query 642 KVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K ++ + + F + AS+M H+ + GV +G +++ E + G L LR
Sbjct 1013 KTVNELASARERVEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLR 1072
Query 701 RERGHVP---------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
R ++ + +A ++A ++YL K VH ++ RN ++++
Sbjct 1073 SLRPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQ------- 1125
Query 752 SPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+K+ D G+ + + + W+APE L G +T D W FG L
Sbjct 1126 DFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGI--FTTHSDVWSFGVVLW 1183
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSFRTIL 863
EI E P Q S + F L E +CP QL L C + P RP+F IL
Sbjct 1184 EIVTLAEQPYQGLSNEQVLKFVMDGGVLEELENCPIQLQELMRLCWQHSPRLRPTFVHIL 1243
Query 864 RDLTRLQPHNLADVLTVNPDSPAS 887
+ +
Sbjct 1244 DRIQDELRPSFRLCSFYYSPECQR 1267
>sp|P70424|ERBB2_MOUSE Receptor tyrosine-protein kinase erbB-2
OS=Mus musculus OX=10090 GN=Erbb2 PE=1 SV=3
Length=1256
Score = 248 bits (633), Expect = 4e-66, Method: Composition-based stats.
Identities = 87/272 (32%), Positives = 133/272 (49%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + VA+K L+ + P+ E ++ + ++ +
Sbjct 727 LGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRL 786
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C +QLV + +P G L D++ H +G LL + QI +GM+YL +
Sbjct 787 LGICLTST---VQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVRLV 843
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W A E + +F +
Sbjct 844 HRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWMALESILRRRFTH 902
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + + +LLE+GERLP+P C
Sbjct 903 QSDVWSYGVTVWELMTFG--------------AKPYDGIPAREIPDLLEKGERLPQPPIC 948
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW ++ RP F L+ +
Sbjct 949 TIDVYMIMVKCWMIDSECRPRFRELVSEFSRM 980
Score = 222 bits (565), Expect = 1e-57, Method: Composition-based stats.
Identities = 69/335 (21%), Positives = 127/335 (38%), Gaps = 39/335 (12%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P +Q + + E+ +L LG G VY+G +G
Sbjct 702 TPSGAVPNQAQMRILKETELRKLKVLGSGAFGTVYKGIWIPDGENV-------------- 747
Query 630 GRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ V +KVL + + A +M+ V +++ + G+C+ +VT+
Sbjct 748 ------KIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQ 800
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ +G L +R RG + + Q+A +SYLE LVH ++ RN+L+
Sbjct 801 LMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVRLVHRDLAARNVLVKSPN-- 858
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+K++D G+ + I W+A E + + D W +G
Sbjct 859 -----HVKITDFGLARLLDIDETEYHADGGKVPIKWMALESIL--RRRFTHQSDVWSYGV 911
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860
T+ E+ G P E ++ RLP+P + + +C + RP FR
Sbjct 912 TVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFR 971
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895
++ + +R+ V+ N D S P
Sbjct 972 ELVSEFSRMARDPQRFVVIQNEDLGPSSPMDSTFY 1006
>sp|C0LGV0|Y5487_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At5g48740 OS=Arabidopsis thaliana OX=3702
GN=At5g48740 PE=1 SV=1
Length=895
Score = 244 bits (623), Expect = 5e-66, Method: Composition-based stats.
Identities = 74/303 (24%), Positives = 121/303 (40%), Gaps = 19/303 (6%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ S +G G FG V G+ VAVK + D
Sbjct 587 MQNWNASRIFSHKEIKSATRNFKEVIGRGSFGAVYRG-----KLPDGKQVAVKV-RFDRT 640
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PR 992
+ E+ +L + H++++ ++G C + + LV EY+ GSL D+L R
Sbjct 641 QLGADSFINEVHLLSQIRHQNLVSFEGFCYEPKRQ--ILVYEYLSGGSLADHLYGPRSKR 698
Query 993 HSIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
HS+ L A +G+ YLH IHRD+ + N+LLD D K+ DFGL+K
Sbjct 699 HSLNWVSRLKVAVDAAKGLDYLHNGSEPRIIHRDVKSSNILLDKDMNAKVSDFGLSKQFT 758
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKF 1108
+ + + + PE + SDV+SFGV L EL+ + S S
Sbjct 759 KADASH-ITTVVKGTAGYLDPEYYSTLQLTEKSDVYSFGVVLLELICGREPLSHSGSPDS 817
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
L+ A+ + E+++ + + + C +AS RP+ ++
Sbjct 818 FNLVLWARPNLQAGAF-EIVDDILKETFDPASMKKAASIAIRCVGRDASGRPSIAEVLTK 876
Query 1169 LKT 1171
LK
Sbjct 877 LKE 879
Score = 207 bits (528), Expect = 6e-54, Method: Composition-based stats.
Identities = 69/351 (20%), Positives = 107/351 (30%), Gaps = 49/351 (14%)
Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587
+ + G L A F + I R S +
Sbjct 546 AILLGVSGGALFATFLVFVFMS-IFTRRQRNKERDITRAQLKMQNWNASRIFSHKEIKSA 604
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+G+G+ VY G+L +V +KV
Sbjct 605 TRNFKEVIGRGSFGAVYRGKLPDGK-------------------------QVAVKVRFDR 639
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---RRERG 704
A +F L+SQ+ H +L G C I+V EY+ G L L R +R
Sbjct 640 TQLGADSFINEVHLLSQIRHQNLVSFEGFCYEPKRQILVYEYLSGGSLADHLYGPRSKRH 699
Query 705 HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
+ ++ VA A L YL N ++H +V NILL + K+SD G
Sbjct 700 SLNWVSRLKVAVDAAKGLDYLHNGSEPRIIHRDVKSSNILLDK-------DMNAKVSDFG 752
Query 762 VGLGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
+ +L PE L+ D + FG LLE+ E
Sbjct 753 LSKQFTKADASHITTVVKGTAGYLDPEYYST--LQLTEKSDVYSFGVVLLELICGREPLS 810
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
S SP + L + + + + T++P +I
Sbjct 811 HSGSPDSFNLVLWARPNLQAGAFEIVDDILKE--TFDPASMKKAASIAIRC 859
>sp|Q01279|EGFR_MOUSE Epidermal growth factor receptor OS=Mus
musculus OX=10090 GN=Egfr PE=1 SV=1
Length=1210
Score = 248 bits (632), Expect = 5e-66, Method: Composition-based stats.
Identities = 91/272 (33%), Positives = 134/272 (49%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + VA+K L+ P+ E ++ ++ + H+ +
Sbjct 720 LGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRL 779
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C +QL+ + +P G L DY+ H IG LL + QI +GM YL + +
Sbjct 780 LGICLTST---VQLITQLMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLV 836
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ + VKI DFGLAK + + Y E G P+ W A E + + +
Sbjct 837 HRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHA-EGGKVPIKWMALESILHRIYTH 895
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + ++ +LE+GERLP+P C
Sbjct 896 QSDVWSYGVTVWELMTFGSK--------------PYDGIPASDISSILEKGERLPQPPIC 941
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW +A RP F LI +
Sbjct 942 TIDVYMIMVKCWMIDADSRPKFRELILEFSKM 973
Score = 224 bits (571), Expect = 2e-58, Method: Composition-based stats.
Identities = 66/345 (19%), Positives = 136/345 (39%), Gaps = 39/345 (11%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P +Q + + E ++ LG G VY+G EG
Sbjct 695 TPSGEAPNQAHLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKV-------------- 740
Query 630 GRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ V +K L + + A +M+ V + H+ + G+C+ ++T+
Sbjct 741 ------KIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQ-LITQ 793
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ +G L ++R + ++ + + Q+A ++YLE++ LVH ++ RN+L+
Sbjct 794 LMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLV------ 847
Query 749 EGTSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGA 802
T +K++D G+ LGA +E E I W+A E + + D W +G
Sbjct 848 -KTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRI--YTHQSDVWSYGV 904
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860
T+ E+ G P S+ ++ RLP+P + + +C + RP FR
Sbjct 905 TVWELMTFGSKPYDGIPASDISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFR 964
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
++ + +++ ++ + Y + +
Sbjct 965 ELILEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDM 1009
>sp|Q7XV05|SERK2_ORYSJ LRR receptor kinase SERK2 OS=Oryza sativa
subsp. japonica OX=39947 GN=SERK2 PE=1 SV=1
Length=628
Score = 239 bits (609), Expect = 5e-66, Method: Composition-based stats.
Identities = 70/325 (22%), Positives = 122/325 (38%), Gaps = 20/325 (6%)
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916
R + +V + LG G FGKV
Sbjct 266 WRRRKPEEHFFDVPAEEDPEVHLGQLKRFSLRELQVATDNFSNKNILGRGGFGKVYKGRL 325
Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976
G +VAVK LK + P ++ E++++ H ++++ +G C E+ L
Sbjct 326 -----ADGSLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTER--LL 378
Query 977 VMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028
V Y+ GS+ L + A G++YLH IHRD+ A N
Sbjct 379 VYPYMANGSVASRLRERQPNDPPLEWQTRTRIALGSARGLSYLHDHCDPKIIHRDVKAAN 438
Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
+LLD D +GDFGLAK + + V + APE L K +DV+ +G
Sbjct 439 ILLDEDFEAVVGDFGLAKLMDYKDTH--VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 496
Query 1089 VTLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
+ L EL+T + + + L+ +G + ++ L++ + + +
Sbjct 497 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSGFVEHEVESLI 556
Query 1146 HLMKNCWETEASFRPTFENLIPILK 1170
+ C + RP ++ +L+
Sbjct 557 QVALLCTQGSPMDRPKMSEVVRMLE 581
Score = 196 bits (499), Expect = 1e-51, Method: Composition-based stats.
Identities = 69/324 (21%), Positives = 109/324 (34%), Gaps = 67/324 (21%)
Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + S V + + LG+G VY+GRL
Sbjct 290 QLKRFSLRELQVATDNFSNKNILGRGGFGKVYKGRLADGS-------------------- 329
Query 633 RGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
V +K L L F ++S H +L + G C+ E ++V Y+
Sbjct 330 -----LVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMA 384
Query 692 HGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745
+G + LR R+ P+ W + +A A LSYL + ++H +V NILL
Sbjct 385 NGSVASRLRERQPNDPPLEWQTRTRIALGSARGLSYLHDHCDPKIIHRDVKAANILLDED 444
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800
A + D G+ ++ V I +APE L G + S D +G+
Sbjct 445 FEAV-------VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 495
Query 801 GATLLEICFDGEAPLQSR--SPSEKEHFYQRQHRLPEPSCPQLAT--------------- 843
G LLE+ A +R + + + L E L
Sbjct 496 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSGFVEHEVESL 555
Query 844 --LTSQCLTYEPTQRPSFRTILRD 865
+ C P RP ++R
Sbjct 556 IQVALLCTQGSPMDRPKMSEVVRM 579
>sp|Q95UN8|M3KSL_DROME Mitogen-activated protein kinase kinase
kinase OS=Drosophila melanogaster OX=7227 GN=slpr PE=1 SV=1
Length=1161
Score = 247 bits (631), Expect = 5e-66, Method: Composition-based stats.
Identities = 94/299 (31%), Positives = 126/299 (42%), Gaps = 43/299 (14%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA---DCGPQHRSGW 944
P L +G G F KV YD GE VA+K D + R
Sbjct 133 QPHEIEYNELDIKEVIGSGGFCKVHRGYYD------GEEVAIKIAHQTGEDDMQRMRDNV 186
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA 1004
QE + L HE+I +G C + L LVMEY GSL L I L+ +A
Sbjct 187 LQEAKLFWALKHENIAALRGVCLN---TKLCLVMEYARGGSLNRILA-GKIPPDVLVNWA 242
Query 1005 QQICEGMAYLHA---QHYIHRDLAARNVLLDN--------DRLVKIGDFGLAKAVPEGHE 1053
QI GM YLH IHRDL + NVL+ + +KI DFGLA+ +
Sbjct 243 IQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREM----- 297
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
Y R W PE + + SDVWS+GV L+EL+T P K + +
Sbjct 298 YNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITG-----ETPYKGFDPLS 352
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+A G LP P CP LMK+CW+T+ RP F+ ++ L+++
Sbjct 353 VAYGVAVNT---------LTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESI 402
Score = 214 bits (545), Expect = 2e-55, Method: Composition-based stats.
Identities = 69/420 (16%), Positives = 136/420 (32%), Gaps = 61/420 (15%)
Query 498 QSLRLRKFPIEQQDGAFVLEGWGRSFPSV---------------RELGAALQGCLLRAGD 542
++ + PI + G G + ++ E+ L +GD
Sbjct 36 HHPQIPEIPIPDLEQVETQVGDGSLWTALYDYDAQGEDELTLRRGEIVVVLSTDSEVSGD 95
Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTN 602
+ + + + + + + H ++ E+ +G G
Sbjct 96 VGWWTGKIGDKVGVFPKDFVTDEDPLQLNVSSAIGDIQPHEIEYNELDIKEVIGSGGFCK 155
Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD----IALAFYET 658
V+ G E V +K+ + D + +
Sbjct 156 VHRGYYDGE--------------------------EVAIKIAHQTGEDDMQRMRDNVLQE 189
Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQL 718
A L + H ++A + GVC+ + +V EY G L+ L G +P + A Q+
Sbjct 190 AKLFWALKHENIAALRGVCL-NTKLCLVMEYARGGSLNRIL---AGKIPPDVLVNWAIQI 245
Query 719 ASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT-SPFIKLSDPGVGLGALS--REER 772
A ++YL N +++H ++ N+L+ +K++D G+ + R
Sbjct 246 ARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMSA 305
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH---FYQR 829
W+ PE + ++ S D W +G L E+ GE P + P +
Sbjct 306 AGTYAWMPPEVIS--VSTYSKFSDVWSYGVLLWELI-TGETPYKGFDPLSVAYGVAVNTL 362
Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
+P+ L C +P +RP F+ IL+ L + +
Sbjct 363 TLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIACSKFTLTPQESFHYMQECW 422
>sp|A9SY39|M3K1A_PHYPA Mitogen-activated protein kinase kinase
kinase 1a OS=Physcomitrium patens OX=3218 GN=MEKK1a PE=2 SV=2
Length=759
Score = 242 bits (617), Expect = 5e-66, Method: Composition-based stats.
Identities = 79/275 (29%), Positives = 128/275 (47%), Gaps = 31/275 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA----DCGPQHRSGWKQEIDILR 952
K LG G FG V G AVK + G Q ++EI +L
Sbjct 426 WAKGEFLGSGTFGSVYEGVAR-----NGTFFAVKEVNLADEGKLGRQAVKQLEREIALLS 480
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
+ H +I++Y G ++ E L + +E + GSL + ++ + Q+ + +QI G+
Sbjct 481 DIQHPNIVQYLG--TERTEDKLYIFLELLNKGSLANLYRKYGLFYEQIKAYTEQILTGLK 538
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
YLH + IHRD+ N+L+D + +VK+ DFG+AK V E + + W APE
Sbjct 539 YLHDRKIIHRDIKCANILVDTNGVVKLADFGMAKQV----EKFGFAKSFVGSAHWMAPEV 594
Query 1073 LK-EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + ++ +A+D+WS G T+ E+ T + PP LE I + + RG
Sbjct 595 VDPKQQYNFAADIWSLGCTVLEMAT-----EGPPFGELEFIAVFW----------KIGRG 639
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
E PD E+ + C + +AS RPT + L+
Sbjct 640 EAPLIPDDLEDELKDFIAQCLQVDASKRPTCDMLL 674
Score = 193 bits (491), Expect = 8e-50, Method: Composition-based stats.
Identities = 63/294 (21%), Positives = 110/294 (37%), Gaps = 42/294 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
R + LG GT +VYEG R +E + DE L +
Sbjct 419 KRPPWDTWAKGEFLGSGTFGSVYEGVARNGTFFAVKEVNLADEGKLGRQ---------AV 469
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
K L+ +L+S + H ++ G + + E + G L L R
Sbjct 470 KQLE-----------REIALLSDIQHPNIVQYLGTERTEDKLYIFLELLNKGSLAN-LYR 517
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
+ G +Q+ + L YL ++ ++H ++ NIL+ T+ +KL+D G
Sbjct 518 KYGLF-YEQIKAYTEQILTGLKYLHDRKIIHRDIKCANILVD-------TNGVVKLADFG 569
Query 762 VGLGALS---REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ + V W+APE + + A D W G T+LE+ +G P
Sbjct 570 MAKQVEKFGFAKSFVGSAHWMAPEVV-DPKQQYNFAADIWSLGCTVLEMATEG-PPFGEL 627
Query 819 SPSEKEHFYQRQHR-----LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
E + + R +P+ +L +QCL + ++RP+ +L
Sbjct 628 ---EFIAVFWKIGRGEAPLIPDDLEDELKDFIAQCLQVDASKRPTCDMLLAHPF 678
>sp|P10533|RMIL_AVII1 Serine/threonine-protein kinase-transforming
protein Rmil OS=Avian retrovirus IC10 OX=11874 GN=V-RMIL
PE=3 SV=1
Length=367
Score = 231 bits (588), Expect = 6e-66, Method: Composition-based stats.
Identities = 76/306 (25%), Positives = 130/306 (42%), Gaps = 31/306 (10%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+ + +SD + + +G G FG V + VAVK L
Sbjct 45 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-------DVAVKMLNV 97
Query 935 DC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991
PQ +K E+ +LR H +I+ + G + L +V ++ SL +L
Sbjct 98 TAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY---STKPQLAIVTQWCEGSSLYHHLHII 154
Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
+ +L+ A+Q +GM YLHA+ IHRDL + N+ L D VKIGDFGLA
Sbjct 155 ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRW 214
Query 1052 HEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQ--SPPT 1106
++ E + W APE ++ + + + SDV++FG+ LYEL+T +
Sbjct 215 SGSHQF-EQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRD 273
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ + ++G + ++ CP + LM C + + RP F ++
Sbjct 274 QIIFMVGRGYLSPDLSKVR------------SNCPKAMKRLMAECLKKKRDERPLFPQIL 321
Query 1167 PILKTV 1172
++ +
Sbjct 322 ASIELL 327
Score = 222 bits (565), Expect = 7e-63, Method: Composition-based stats.
Identities = 67/327 (20%), Positives = 120/327 (37%), Gaps = 53/327 (16%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSF-HRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
P P R +TL S + +IT +G G+ VY+G+ +
Sbjct 30 PGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD 89
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSHTH 669
V +K+L+ + AF ++ + H +
Sbjct 90 ---------------------------VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVN 122
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729
+ G + P+ +VT++ E L L M + +A+Q A + YL K+
Sbjct 123 ILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKS 181
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPEC 783
++H ++ NI L +K+ D G+ G+ E+ I W+APE
Sbjct 182 IIHRDLKSNNIFLHE-------DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEV 234
Query 784 LPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP------ 836
+ N S D + FG L E+ G+ P + + ++ F + L
Sbjct 235 IRMQDKNPYSFQSDVYAFGIVLYELM-TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRS 293
Query 837 SCPQ-LATLTSQCLTYEPTQRPSFRTI 862
+CP+ + L ++CL + +RP F I
Sbjct 294 NCPKAMKRLMAECLKKKRDERPLFPQI 320
>sp|Q93ZS4|NIK3_ARATH Protein NSP-INTERACTING KINASE 3 OS=Arabidopsis
thaliana OX=3702 GN=NIK3 PE=1 SV=1
Length=632
Score = 239 bits (609), Expect = 6e-66, Method: Composition-based stats.
Identities = 71/324 (22%), Positives = 127/324 (39%), Gaps = 19/324 (6%)
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916
+R + + +V + + LG G +G V
Sbjct 261 WRYRRNKQIFFDVNEQYDPEVSLGHLKRYTFKELRSATNHFNSKNILGRGGYGIVYKG-- 318
Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976
+ G +VAVK LK ++ E++ + H ++++ +G C E+ L
Sbjct 319 ---HLNDGTLVAVKRLKDCNIAGGEVQFQTEVETISLALHRNLLRLRGFCSSNQER--IL 373
Query 977 VMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028
V Y+P GS+ L + ++ ++ A G+ YLH Q IHRD+ A N
Sbjct 374 VYPYMPNGSVASRLKDNIRGEPALDWSRRKKIAVGTARGLVYLHEQCDPKIIHRDVKAAN 433
Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
+LLD D +GDFGLAK + + V V APE L + +DV+ FG
Sbjct 434 ILLDEDFEAVVGDFGLAKLLDHRDSH--VTTAVRGTVGHIAPEYLSTGQSSEKTDVFGFG 491
Query 1089 VTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
+ L EL+T + + + ++ + +L +L+++ E+
Sbjct 492 ILLLELITGQKALDFGRSAHQKGVMLDWVKKLHQEGKLKQLIDKDLNDKFDRVELEEIVQ 551
Query 1147 LMKNCWETEASFRPTFENLIPILK 1170
+ C + S RP ++ +L+
Sbjct 552 VALLCTQFNPSHRPKMSEVMKMLE 575
Score = 193 bits (491), Expect = 1e-50, Method: Composition-based stats.
Identities = 62/323 (19%), Positives = 108/323 (33%), Gaps = 66/323 (20%)
Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
+L + +F + + LG+G VY+G L
Sbjct 285 HLKRYTFKELRSATNHFNSKNILGRGGYGIVYKGHLNDG--------------------- 323
Query 633 RGQELRVVLKVLDPSH-HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
V +K L + + F +S H +L + G C E I+V Y+
Sbjct 324 ----TLVAVKRLKDCNIAGGEVQFQTEVETISLALHRNLLRLRGFCSSNQERILVYPYMP 379
Query 692 HGPLDVWLRRE---RGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745
+G + L+ + + + +A A L YL + ++H +V NILL
Sbjct 380 NGSVASRLKDNIRGEPALDWSRRKKIAVGTARGLVYLHEQCDPKIIHRDVKAANILLDED 439
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800
A + D G+ R+ V + +APE L G + S D +GF
Sbjct 440 FEAV-------VGDFGLAKLLDHRDSHVTTAVRGTVGHIAPEYLSTGQS--SEKTDVFGF 490
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP------------------SCPQLA 842
G LLE+ +A RS +K +L + ++
Sbjct 491 GILLLELITGQKALDFGRSAHQKGVMLDWVKKLHQEGKLKQLIDKDLNDKFDRVELEEIV 550
Query 843 TLTSQCLTYEPTQRPSFRTILRD 865
+ C + P+ RP +++
Sbjct 551 QVALLCTQFNPSHRPKMSEVMKM 573
>sp|Q9LXA5|LRK91_ARATH L-type lectin-domain containing receptor
kinase IX.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK91 PE=1
SV=1
Length=651
Score = 239 bits (610), Expect = 6e-66, Method: Composition-based stats.
Identities = 69/285 (24%), Positives = 123/285 (43%), Gaps = 18/285 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R LGEG FG V + + MVA+K A Q + + E+ I+ +L
Sbjct 333 NNFADDRKLGEGGFGAVYRGYLNSLD----MMVAIKKF-AGGSKQGKREFVTEVKIISSL 387
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMA 1012
H ++++ G C ++ E ++ E++P GSL +L + + + +
Sbjct 388 RHRNLVQLIGWCHEKDE--FLMIYEFMPNGSLDAHLFGKKPHLAWHVRCKITLGLASALL 445
Query 1013 YLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH Q +HRD+ A NV+LD++ K+GDFGLA+ + HE + A
Sbjct 446 YLHEEWEQCVVHRDIKASNVMLDSNFNAKLGDFGLARLM--DHELGPQTTGLAGTFGYMA 503
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL---RLTE 1126
PE + + SDV+SFGV E++T S + + + + + +
Sbjct 504 PEYISTGRASKESDVYSFGVVTLEIVTGRKSVDRRQGRVEPVTNLVEKMWDLYGKGEVIT 563
Query 1127 LLERGERLPRPDKCPCEVYHLM-KNCWETEASFRPTFENLIPILK 1170
++ R+ D+ E ++ C + + RP+ + I +L
Sbjct 564 AIDEKLRIGGFDEKQAECLMIVGLWCAHPDVNTRPSIKQAIQVLN 608
Score = 226 bits (576), Expect = 2e-61, Method: Composition-based stats.
Identities = 59/285 (21%), Positives = 97/285 (34%), Gaps = 47/285 (16%)
Query 540 AGDDCFSLRRCCLPQPGETSNLIIMRGA---RASPRTLNLSQLSFHRVDQKEITQLSHLG 596
F R+ + ET NL + A PR L+ LG
Sbjct 286 TSLIVFLKRKQQKKKAEETENLTSINEDLERGAGPRKFTYKDLAS---AANNFADDRKLG 342
Query 597 QGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFY 656
+G VY G L ++ V +K F
Sbjct 343 EGGFGAVYRGYLNSL------------------------DMMVAIKKFAGGSKQGKREFV 378
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
++S + H +L + G C E +M+ E++ +G LD L ++ H+ + +
Sbjct 379 TEVKIISSLRHRNLVQLIGWCHEKDEFLMIYEFMPNGSLDAHLFGKKPHLAWHVRCKITL 438
Query 717 QLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-----GALS 768
LASAL YL + +VH ++ N++L ++ KL D G+
Sbjct 439 GLASALLYLHEEWEQCVVHRDIKASNVMLD-------SNFNAKLGDFGLARLMDHELGPQ 491
Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
++APE + G S D + FG LEI ++
Sbjct 492 TTGLAGTFGYMAPEYISTGRA--SKESDVYSFGVVTLEIVTGRKS 534
>sp|Q9LUT0|CARK1_ARATH Receptor-like cytoplasmic kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=CARK1 PE=1 SV=1
Length=364
Score = 230 bits (587), Expect = 6e-66, Method: Composition-based stats.
Identities = 73/284 (26%), Positives = 120/284 (42%), Gaps = 24/284 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG +G+V +G+ A+K L D Q + ++ ++ L E+++
Sbjct 75 IGEGSYGRVFYGILK-----SGKAAAIKKL--DSSKQPDQEFLAQVSMVSRLRQENVVAL 127
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------IGLAQLLLFAQQICEGMA 1012
G C D + L EY P GSL D L + Q + A G+
Sbjct 128 LGYCVDGPLR--VLAYEYAPNGSLHDILHGRKGVKGAQPGPVLSWHQRVKIAVGAARGLE 185
Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH + H IHRD+ + NVLL +D + KI DF L+ P+ ++A
Sbjct 186 YLHEKANPHVIHRDIKSSNVLLFDDDVAKIADFDLSNQAPD-MAARLHSTRVLGTFGYHA 244
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE SDV+SFGV L ELLT + P ++ A +++ ++ + +
Sbjct 245 PEYAMTGTLSTKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSVVTWATPKLSEDKVKQCV 304
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ P K ++ + C + EA FRP ++ L+ +
Sbjct 305 DARLNGEYPPKAVAKLAAVAALCVQYEADFRPNMSIVVKALQPL 348
Score = 202 bits (515), Expect = 3e-56, Method: Composition-based stats.
Identities = 74/388 (19%), Positives = 130/388 (34%), Gaps = 85/388 (22%)
Query 547 LRRCCLPQPGETSNLIIMRGA---RASPRT----LNLSQLSFHRVDQKEITQL------- 592
RR P N G RA P + + +S + E+ +
Sbjct 13 FRRVSETGPKPVHNTGGYNGGHHQRADPPKNLPVIQMQPISVAAIPADELRDITDNYGSK 72
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
S +G+G+ V+ G L+ +K LD S
Sbjct 73 SLIGEGSYGRVFYGILKSGK-------------------------AAAIKKLD-SSKQPD 106
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-------- 704
F S++S++ ++ + G CV GP ++ EY +G L L +G
Sbjct 107 QEFLAQVSMVSRLRQENVVALLGYCVDGPLRVLAYEYAPNGSLHDILHGRKGVKGAQPGP 166
Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
+ ++ +A A L YL K +++H ++ N+LL K++D
Sbjct 167 VLSWHQRVKIAVGAARGLEYLHEKANPHVIHRDIKSSNVLL-------FDDDVAKIADFD 219
Query 762 VG------LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
+ L + + APE G +LST D + FG LLE+ G P+
Sbjct 220 LSNQAPDMAARLHSTRVLGTFGYHAPEYAMTG--TLSTKSDVYSFGVVLLELL-TGRKPV 276
Query 816 QSRSPSEKEHFYQR------------------QHRLPEPSCPQLATLTSQCLTYEPTQRP 857
P ++ P + +LA + + C+ YE RP
Sbjct 277 DHTLPRGQQSVVTWATPKLSEDKVKQCVDARLNGEYPPKAVAKLAAVAALCVQYEADFRP 336
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSP 885
+ +++ L L + T + +
Sbjct 337 NMSIVVKALQPLLNPPRSAPQTPHRNPY 364
>sp|Q6ZCZ2|BRL3_ORYSJ Brassinosteroid LRR receptor kinase BRL3
OS=Oryza sativa subsp. japonica OX=39947 GN=BRL3 PE=2 SV=1
Length=1214
Score = 247 bits (631), Expect = 6e-66, Method: Composition-based stats.
Identities = 80/367 (22%), Positives = 141/367 (38%), Gaps = 25/367 (7%)
Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
++L + + + + C P S + L + + + +
Sbjct 848 HYKLWKFHKNKTKEIQAGCSESLPGSSKSSWKLSGIGEPLSINMAIFENPLRKLTFSDLH 907
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ + + +G G FG+V G +VAVK L G R + E++
Sbjct 908 QATNGFCAETL--IGSGGFGEVYKAKLK-----DGNIVAVKKLMHFTGQGDRE-FTAEME 959
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFA 1004
+ + H +++ G C+ E+ LV EY+ GSL L + A A
Sbjct 960 TIGKIKHRNLVPLLGYCKIGDER--LLVYEYMKNGSLDFVLHDKGEANMDLNWATRKKIA 1017
Query 1005 QQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
G+A+LH H IHRD+ + NVLLD + + DFG+A+ + + V
Sbjct 1018 IGSARGLAFLHHSCVPHIIHRDMKSSNVLLDGNFDAYVSDFGMARLMNALDSHLTVSMLS 1077
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
+P + PE ++++ DV+S+GV L ELLT L+G + QM
Sbjct 1078 GTP-GYVPPEYCQDFRCTTKGDVYSYGVVLLELLTGKKPIDPTEFGDSNLVGWVK-QMVE 1135
Query 1122 LRLTELLERGERLPRPDKCPCEVYH---LMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
R +E+ + + E+Y + C + + + RPT ++ + K
Sbjct 1136 DRCSEIYDPTLMATTSSE--LELYQYLKIACRCLDDQPNRRPTMIQVMTMFKEFQVDSGS 1193
Query 1179 QAPSVFS 1185
FS
Sbjct 1194 NFLDDFS 1200
Score = 206 bits (525), Expect = 7e-53, Method: Composition-based stats.
Identities = 67/376 (18%), Positives = 127/376 (34%), Gaps = 79/376 (21%)
Query 527 RELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ 586
+E+ A L + + L P + N+ I R L S L
Sbjct 860 KEIQAGCSESLPGSSKSSWKLSGIGEPL---SINMAIFENPL---RKLTFSDLHQ---AT 910
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ +G G VY+ +L+ V +K L
Sbjct 911 NGFCAETLIGSGGFGEVYKAKLKDGNI-------------------------VAVKKLMH 945
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGH 705
F + ++ H +L + G C G E ++V EY+++G LD L + +
Sbjct 946 FTGQGDREFTAEMETIGKIKHRNLVPLLGYCKIGDERLLVYEYMKNGSLDFVLHDKGEAN 1005
Query 706 VPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ + W + +A A L++L + +++H ++ N+LL A +SD
Sbjct 1006 MDLNWATRKKIAIGSARGLAFLHHSCVPHIIHRDMKSSNVLLDGNFDAY-------VSDF 1058
Query 761 GVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ L+ ++ PE +T D + +G LLE+ G+ P
Sbjct 1059 GMARLMNALDSHLTVSMLSGTPGYVPPEYCQD--FRCTTKGDVYSYGVVLLELL-TGKKP 1115
Query 815 LQSRSPSE--KEHFYQRQHRLPEPSCPQLAT------------------LTSQCLTYEPT 854
P+E + ++ E C ++ + +CL +P
Sbjct 1116 ---IDPTEFGDSNLVGWVKQMVEDRCSEIYDPTLMATTSSELELYQYLKIACRCLDDQPN 1172
Query 855 QRPSFRTILRDLTRLQ 870
+RP+ ++ Q
Sbjct 1173 RRPTMIQVMTMFKEFQ 1188
>sp|Q60700|M3K12_MOUSE Mitogen-activated protein kinase kinase
kinase 12 OS=Mus musculus OX=10090 GN=Map3k12 PE=1 SV=1
Length=888
Score = 244 bits (622), Expect = 7e-66, Method: Composition-based stats.
Identities = 81/301 (27%), Positives = 123/301 (41%), Gaps = 35/301 (12%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ + D + ++ +G G G V L + GE VAVK
Sbjct 132 WTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFH------GEEVAVK 185
Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
++ I LR L H +II +KG C ++ME+ G L + L
Sbjct 186 KVRDLKETD--------IKHLRKLKHPNIITFKGVCTQA--PCYCILMEFCAQGQLYEVL 235
Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
+ + L+ ++ I GM YLH IHRDL + N+L+ D +VKI DFG +K +
Sbjct 236 RAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELS 295
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
+ + V W APE ++ D+WSFGV L+ELLT P K +
Sbjct 296 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG-----EIPYKDV 346
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ I G + LP P CP L++ CW ++ RP+F ++ L
Sbjct 347 DSSAIIWGVGSN---------SLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHL 397
Query 1170 K 1170
Sbjct 398 D 398
Score = 203 bits (516), Expect = 2e-52, Method: Composition-based stats.
Identities = 94/475 (20%), Positives = 161/475 (34%), Gaps = 94/475 (20%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+A Q V +EI L +G G + V+ G
Sbjct 136 GKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLG-------------------- 175
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
R G+E+ V KV D D + ++ H ++ GVC + P ++
Sbjct 176 ----RFHGEEVAVK-KVRDLKETD--------IKHLRKLKHPNIITFKGVCTQAPCYCIL 222
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
E+ G L LR R P + + + +A ++YL ++H ++ N+L+
Sbjct 223 MEFCAQGQLYEVLRAGRPVTP-SLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLIT--- 278
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+K+SD G + ++ + W+APE + +S +D W FG
Sbjct 279 ----YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 332
Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
L E+ GE P + S +P L QC +P RPSFR
Sbjct 333 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFR 391
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920
IL L L+ S A +V L+ +
Sbjct 392 QILLHLDIASADVLSTPQETYFKSQAEWRE-------------------EVKLHFEKIKS 432
Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
+GT L+ + + R + +DI + E + E++ L Y
Sbjct 433 EGTCLH----RLEEELVMRRREELRHALDI------------REHYERKLERANNL---Y 473
Query 981 VPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH-AQHYIHRD-----LAARNV 1029
+ L +L L L + ++ C G+ H ++ +H + + RNV
Sbjct 474 MELNALMLQLELKERELLRREQALERRCPGLLKSHPSRGLLHGNTMEKLIKKRNV 528
>sp|P53669|LIMK1_RAT LIM domain kinase 1 OS=Rattus norvegicus
OX=10116 GN=Limk1 PE=1 SV=1
Length=647
Score = 239 bits (609), Expect = 7e-66, Method: Composition-based stats.
Identities = 75/309 (24%), Positives = 132/309 (43%), Gaps = 33/309 (11%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
+F L LG+G FG+ T+ TGE++ +K L + + +
Sbjct 328 CRPHRIFRPSDLIHGEVLGKGCFGQ----AIKVTHRETGEVMVMKEL-IRFDEETQRTFL 382
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLF 1003
+E+ ++R L H +++K+ G +K L + EY+ G+LR + +Q + F
Sbjct 383 KEVKVMRCLEHPNVLKFIGVLYK--DKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSF 440
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY-------- 1055
A+ I GMAYLH+ + IHRDL + N L+ +R V + DFGLA+ + +
Sbjct 441 AKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLARLMIDEKGQSEDLRSLKK 500
Query 1056 ---RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
+ R +W APE + + DV+SFG+ L E++ ++ + ++
Sbjct 501 PDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFG 560
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+G + P CP + + C + + RP+F L L+T+
Sbjct 561 LNVRGFLDRY-------------CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETL 607
Query 1173 HEKYQGQAP 1181
G P
Sbjct 608 RMHLAGHLP 616
Score = 208 bits (529), Expect = 2e-55, Method: Composition-based stats.
Identities = 59/308 (19%), Positives = 111/308 (36%), Gaps = 54/308 (18%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ LG+G + R G +V+K L
Sbjct 336 PSDLIHGEVLGKGCFGQAIKVTHRETGE------------------------VMVMKELI 371
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ F + +M + H ++ GV + +TEY++ G L ++
Sbjct 372 RFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQ 431
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL- 764
P + ++ A+ +AS ++YL + N++H ++ N L+ + + ++D G+
Sbjct 432 YPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRE-------NRNVVVADFGLARL 484
Query 765 -----------------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
R V W+APE + G S +D + FG L EI
Sbjct 485 MIDEKGQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMING--RSYDEKVDVFSFGIVLCEI 542
Query 808 C--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILR 864
+ + R+ + R P+CP +T +C +P +RPSF + +
Sbjct 543 IGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQ 602
Query 865 DLTRLQPH 872
L L+ H
Sbjct 603 WLETLRMH 610
>sp|Q64716|INSRR_RAT Insulin receptor-related protein OS=Rattus
norvegicus OX=10116 GN=Insrr PE=1 SV=3
Length=1300
Score = 248 bits (632), Expect = 7e-66, Method: Composition-based stats.
Identities = 95/329 (29%), Positives = 154/329 (47%), Gaps = 36/329 (11%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT-GEMVAV 929
++ D + + IR+LG+G FG V G VA+
Sbjct 953 YTSVNPEYFSASHMYVPDEWEVPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVAL 1012
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K + + R + +E +++ H+++ G QG+ +L ++ME + G L+ +
Sbjct 1013 KTVNELASARERVEFLKEASVMKAFKCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSH 1070
Query 990 LP------RHSIGLAQ-----LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
L ++ GL Q ++ A +I +GMAYL A+ ++HRDLAARN ++ D VK
Sbjct 1071 LRSLRPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQDFTVK 1130
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
IGDFG+ + V E +YYR G PV W APE LK+ F SDVWSFGV L+E++T
Sbjct 1131 IGDFGMTRDVYE-TDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVT-- 1187
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
L ++ ++ + + G L + CP ++ LM+ CW+
Sbjct 1188 ------------LAEQPYQGLSNEQVLKFVMDGGVLEEQEDCPIQLQELMRRCWQHTPRL 1235
Query 1159 RPTFENLIPILKTVHEKYQGQAPSVFSVC 1187
RPTF + IL + ++ + F +C
Sbjct 1236 RPTF---VHILDRIQDELRPS----FRLC 1257
Score = 241 bits (614), Expect = 1e-63, Method: Composition-based stats.
Identities = 74/324 (23%), Positives = 123/324 (38%), Gaps = 46/324 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
V +++I + LGQG+ VYEG R +G+ + V L
Sbjct 972 WEVPREQIAIIRELGQGSFGMVYEGLARGLEAGE-------------------ESTPVAL 1012
Query 642 KVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K ++ + + F + AS+M H+ + GV +G +++ E + G L LR
Sbjct 1013 KTVNELASARERVEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLR 1072
Query 701 RERGHVP---------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
R ++ + +A ++A ++YL K VH ++ RN ++++
Sbjct 1073 SLRPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQ------- 1125
Query 752 SPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+K+ D G+ + + + W+APE L G +T D W FG L
Sbjct 1126 DFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGI--FTTHSDVWSFGVVLW 1183
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTIL 863
EI E P Q S + F L E CP QL L +C + P RP+F IL
Sbjct 1184 EIVTLAEQPYQGLSNEQVLKFVMDGGVLEEQEDCPIQLQELMRRCWQHTPRLRPTFVHIL 1243
Query 864 RDLTRLQPHNLADVLTVNPDSPAS 887
+ +
Sbjct 1244 DRIQDELRPSFRLCSFYYSPECQR 1267
>sp|Q8BKG3|PTK7_MOUSE Inactive tyrosine-protein kinase 7 OS=Mus
musculus OX=10090 GN=Ptk7 PE=1 SV=1
Length=1062
Score = 246 bits (628), Expect = 7e-66, Method: Composition-based stats.
Identities = 91/335 (27%), Positives = 144/335 (43%), Gaps = 30/335 (9%)
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
+CL P Q +++ L T S L+ I LG+
Sbjct 738 MECLNGGPLQNGQPSAEIQEEVALTSLGSGPPATNKRHSAGDRMHFPRAS-LQPITTLGK 796
Query 906 GHFGKVSLYCYDPTNDG-TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG 964
FG+V L +G T +V VK+L Q + +++E+++ L H ++++ G
Sbjct 797 SEFGEVFLAKAQGVEEGATETLVLVKSL-QSRDEQQQLDFRREVEMFGKLNHANVVRLLG 855
Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQLLLFAQQICEGMAYL 1014
C + +V+EYV LG L+ +L + Q + Q+ GM +L
Sbjct 856 LCREAEPH--YMVLEYVDLGDLKQFLRISKNKDEKLKSQPLSTKQKVALCSQVALGMEHL 913
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
++H+DLAARN L+ R VK+ GL+K V Y+ P+ W +PE +
Sbjct 914 SNNRFVHKDLAARNCLISAQRQVKVSALGLSKDVYNSEYYHF--RQAWVPLRWMSPEAVL 971
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
E F SDVW+FGV ++E+ TH + GQ L +L RL
Sbjct 972 EGDFSTKSDVWAFGVLMWEVFTHGEMPHG-------------GQADDEVLADLQAGKARL 1018
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P+P+ CP ++Y LM+ CW RP+F + L
Sbjct 1019 PQPEGCPSKLYRLMQRCWAPNPKDRPSFSEIASTL 1053
Score = 223 bits (569), Expect = 2e-58, Method: Composition-based stats.
Identities = 77/338 (23%), Positives = 130/338 (38%), Gaps = 47/338 (14%)
Query 544 CFSLRRCCLPQPG-ETSNLIIMRGARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTR 600
C + QP E + + + P N + R+ + + ++ LG+
Sbjct 740 CLNGGPLQNGQPSAEIQEEVALTSLGSGPPATNKRHSAGDRMHFPRASLQPITTLGKSEF 799
Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660
V+ + + G E V++K L L F
Sbjct 800 GEVFLAKAQGVEEG-------------------ATETLVLVKSLQSRDEQQQLDFRREVE 840
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH------VPMAWKMVV 714
+ +++H ++ + G+C + MV EYV+ G L +LR + P++ K V
Sbjct 841 MFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKNKDEKLKSQPLSTKQKV 900
Query 715 AQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
A Q+A + +L N VH ++ RN L++ +K+S G+ + E
Sbjct 901 ALCSQVALGMEHLSNNRFVHKDLAARNCLIS-------AQRQVKVSALGLSKDVYNSEYY 953
Query 773 VER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HF 826
R + W++PE + G ST D W FG + E+ GE P ++ E
Sbjct 954 HFRQAWVPLRWMSPEAVLEG--DFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADL 1011
Query 827 YQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862
+ RLP+P CP +L L +C P RPSF I
Sbjct 1012 QAGKARLPQPEGCPSKLYRLMQRCWAPNPKDRPSFSEI 1049
>sp|P00532|RAF_MSV36 Serine/threonine-protein kinase-transforming
protein raf OS=Murine sarcoma virus 3611 OX=11812 GN=V-RAF
PE=3 SV=1
Length=323
Score = 229 bits (583), Expect = 8e-66, Method: Composition-based stats.
Identities = 77/303 (25%), Positives = 128/303 (42%), Gaps = 31/303 (10%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCG 937
+S + +G G FG V + VAVK LK D
Sbjct 6 RPRGQRDSSYYWKMEASEVMLSTRIGSGSFGTVYKGKWHG-------DVAVKILKVVDPT 58
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSI 995
P+ ++ E+ +LR H +I+ + G + +L +V ++ SL +L
Sbjct 59 PEQLQAFRNEVAVLRKTRHVNILLFMGYM---TKDNLAIVTQWCEGSSLYKHLHVQETKF 115
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ QL+ A+Q +GM YLHA++ IHRD+ + N+ L VKIGDFGLA
Sbjct 116 QMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQ 175
Query 1056 RVREDGDSPVFWYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQS--PPTKFLE 1110
+V E V W APE ++ + F + SDV+S+G+ LYEL+ + +
Sbjct 176 QV-EQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAGELPYAHINNRDQIIF 234
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
++G + RL + CP + L+ +C + RP F ++ ++
Sbjct 235 MVGRGYASPDLSRLYK------------NCPKAIKRLVADCVKKVKEERPLFPQILSSIE 282
Query 1171 TVH 1173
+
Sbjct 283 LLQ 285
Score = 216 bits (550), Expect = 2e-61, Method: Composition-based stats.
Identities = 69/357 (19%), Positives = 125/357 (35%), Gaps = 62/357 (17%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
N I RG R S + +++ E+ + +G G+ VY+G+ +
Sbjct 1 EKNKIRPRGQRDSSY--------YWKMEASEVMLSTRIGSGSFGTVYKGKWHGD------ 46
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQVSHTHLAFVH 674
V +K+L DP+ + AF +++ + H ++
Sbjct 47 ---------------------VAVKILKVVDPTPEQLQ-AFRNEVAVLRKTRHVNILLFM 84
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGN 734
G + +VT++ E L L + M + +A+Q A + YL KN++H +
Sbjct 85 GYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRD 143
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGG- 787
+ NI L +K+ D G+ G+ E+ + W+APE +
Sbjct 144 MKSNNIFLHEGL-------TVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQD 196
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH-------RLPEPSCPQ 840
N S D + +G L E+ GE P + ++ F + RL +
Sbjct 197 DNPFSFQSDVYSYGIVLYELMA-GELPYAHINNRDQIIFMVGRGYASPDLSRLYKNCPKA 255
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897
+ L + C+ +RP F IL + LQ + S
Sbjct 256 IKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSAPEPSLHRAAHTEDINAC 312
>sp|Q23915|KINX_DICDI Probable serine/threonine-protein kinase
kinX OS=Dictyostelium discoideum OX=44689 GN=kinX PE=3 SV=2
Length=1094
Score = 246 bits (628), Expect = 8e-66, Method: Composition-based stats.
Identities = 75/296 (25%), Positives = 125/296 (42%), Gaps = 32/296 (11%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA---DCGPQHRSGWK- 945
L I ++G G FGKV Y G VA+K + D +
Sbjct 15 WSIKYEDLDFISEIGSGGFGKVFKGEYL------GAPVAIKKIHILPDDPNRVDLEKFLN 68
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--F 1003
+EI+ ++ H ++I++ G E+ G L +V E + G L+ YL SI L L
Sbjct 69 REIETIKLFTHPNVIQFVGISENNG--ILFIVTELIEGGDLQYYLKNQSIDLPWFLRANI 126
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
A + M+YLH++ +HRDL + N+L+D + +K+ DFG A+ V E +
Sbjct 127 ALDVSLAMSYLHSKSIVHRDLKSTNLLVDKNWKIKVCDFGFARIVEEDNNKSMT---ICG 183
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
W +PE + + SD++SFG+ L E+++ + +
Sbjct 184 TDNWMSPEMITGLDYDERSDIFSFGIVLLEIISRVKPA-------------PYMRDASFG 230
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L E + R + P CP + L NC + + RP+F+ + LK +
Sbjct 231 LAEDIVRNQL--IPTDCPESLIDLTFNCCSVDPNNRPSFKEISQTLKQIKTTLDSN 284
Score = 216 bits (551), Expect = 3e-56, Method: Composition-based stats.
Identities = 64/331 (19%), Positives = 122/331 (37%), Gaps = 45/331 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ +++ +S +G G V++G E G P V +
Sbjct 15 WSIKYEDLDFISEIGSGGFGKVFKG----EYLGAP----------------------VAI 48
Query 642 KVL-----DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
K + DP+ D+ + +H ++ G+ +VTE +E G L
Sbjct 49 KKIHILPDDPNRVDLEKFLNREIETIKLFTHPNVIQFVGISENNGILFIVTELIEGGDLQ 108
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+L+ + +P + +A ++ A+SYL +K++VH ++ N+L+ + + IK
Sbjct 109 YYLKNQSIDLPWFLRANIALDVSLAMSYLHSKSIVHRDLKSTNLLVDK-------NWKIK 161
Query 757 LSDPGVGLGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
+ D G + I W++PE + G D + FG LLEI +
Sbjct 162 VCDFGFARIVEEDNNKSMTICGTDNWMSPEMITG--LDYDERSDIFSFGIVLLEIISRVK 219
Query 813 A-PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P + R +P L LT C + +P RPSF+ I + L +++
Sbjct 220 PAPYMRDASFGLAEDIVRNQLIPTDCPESLIDLTFNCCSVDPNNRPSFKEISQTLKQIKT 279
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902
++++ + K
Sbjct 280 TLDSNIVYPEIRDFEQQQKISTTNGNNKQNG 310
>sp|P09208|INSR_DROME Insulin-like receptor OS=Drosophila melanogaster
OX=7227 GN=InR PE=1 SV=3
Length=2144
Score = 249 bits (635), Expect = 8e-66, Method: Composition-based stats.
Identities = 88/324 (27%), Positives = 147/324 (45%), Gaps = 41/324 (13%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN-DGTGEMVAV 929
N D + + ++ LG+G FG V +G A+
Sbjct 1345 HMNTEVNPFYASMQYIPDDWEVLRENIIQLAPLGQGSFGMVYEGILKSFPPNGVDRECAI 1404
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K + + + R+ + E +++ H+++ G C +G+ +L +VME + G L+ Y
Sbjct 1405 KTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVC-SRGQPAL-VVMELMKKGDLKSY 1462
Query 990 LPRHSIGL-----------------------AQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
L H ++ A +I +GMAYL A+ ++HRDLAA
Sbjct 1463 LRAHRPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAA 1522
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RN ++ +D VKIGDFG+ + + E +YYR G PV W PE L++ + ASDV+S
Sbjct 1523 RNCMVADDLTVKIGDFGMTRDIYE-TDYYRKGTKGLLPVRWMPPESLRDGVYSSASDVFS 1581
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
FGV L+E+ T L ++ ++ + G + RP+ CP ++
Sbjct 1582 FGVVLWEMAT--------------LAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHK 1627
Query 1147 LMKNCWETEASFRPTFENLIPILK 1170
LM+ CW +S RP+F ++I L+
Sbjct 1628 LMQRCWHHRSSARPSFLDIIAYLE 1651
Score = 232 bits (592), Expect = 1e-60, Method: Composition-based stats.
Identities = 76/362 (21%), Positives = 123/362 (34%), Gaps = 63/362 (17%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
V ++ I QL+ LGQG+ VYEG L+ G +
Sbjct 1362 DDWEVLRENIIQLAPLGQGSFGMVYEGILKSFPP-------------------NGVDREC 1402
Query 640 VLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+K ++ + D F AS+M + H+ + GVC RG ++V E ++ G L +
Sbjct 1403 AIKTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSY 1462
Query 699 LRRERG---------------------HVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737
LR R +A ++A ++YL K VH ++
Sbjct 1463 LRAHRPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAA 1522
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSL 791
RN ++A +K+ D G+ + + + W+ PE L G
Sbjct 1523 RNCMVA-------DDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGV--Y 1573
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCL 849
S+A D + FG L E+ P Q S + + + PE L L +C
Sbjct 1574 SSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCW 1633
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
+ + RPSF I+ L S R ++ F
Sbjct 1634 HHRSSARPSFLDIIAYLE-----PQCPNSQFKEVSFYHSEAGLQHREKERKERNQLDAFA 1688
Query 910 KV 911
V
Sbjct 1689 AV 1690
>sp|Q12852|M3K12_HUMAN Mitogen-activated protein kinase kinase
kinase 12 OS=Homo sapiens OX=9606 GN=MAP3K12 PE=1 SV=2
Length=859
Score = 243 bits (620), Expect = 9e-66, Method: Composition-based stats.
Identities = 81/301 (27%), Positives = 123/301 (41%), Gaps = 35/301 (12%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ + D + ++ +G G G V L + GE VAVK
Sbjct 99 WTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFH------GEEVAVK 152
Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
++ I LR L H +II +KG C ++ME+ G L + L
Sbjct 153 KVRDLKETD--------IKHLRKLKHPNIITFKGVCTQA--PCYCILMEFCAQGQLYEVL 202
Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
+ + L+ ++ I GM YLH IHRDL + N+L+ D +VKI DFG +K +
Sbjct 203 RAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELS 262
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
+ + V W APE ++ D+WSFGV L+ELLT P K +
Sbjct 263 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG-----EIPYKDV 313
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ I G + LP P CP L++ CW ++ RP+F ++ L
Sbjct 314 DSSAIIWGVGSN---------SLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHL 364
Query 1170 K 1170
Sbjct 365 D 365
Score = 201 bits (512), Expect = 4e-52, Method: Composition-based stats.
Identities = 67/305 (22%), Positives = 109/305 (36%), Gaps = 50/305 (16%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+A Q V +EI L +G G + V+ G
Sbjct 103 GKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLG-------------------- 142
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
R G+E+ V KV D D + ++ H ++ GVC + P ++
Sbjct 143 ----RFHGEEVAVK-KVRDLKETD--------IKHLRKLKHPNIITFKGVCTQAPCYCIL 189
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
E+ G L LR R P + + + +A ++YL ++H ++ N+L+
Sbjct 190 MEFCAQGQLYEVLRAGRPVTP-SLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLIT--- 245
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+K+SD G + ++ + W+APE + +S +D W FG
Sbjct 246 ----YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 299
Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
L E+ GE P + S +P L QC +P RPSFR
Sbjct 300 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFR 358
Query 861 TILRD 865
IL
Sbjct 359 QILLH 363
>sp|P06494|ERBB2_RAT Receptor tyrosine-protein kinase erbB-2 OS=Rattus
norvegicus OX=10116 GN=Erbb2 PE=1 SV=3
Length=1257
Score = 247 bits (631), Expect = 9e-66, Method: Composition-based stats.
Identities = 87/272 (32%), Positives = 133/272 (49%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + VA+K L+ + P+ E ++ + ++ +
Sbjct 728 LGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRL 787
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C +QLV + +P G L D++ H +G LL + QI +GM+YL +
Sbjct 788 LGICLTST---VQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLV 844
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W A E + +F +
Sbjct 845 HRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWMALESILRRRFTH 903
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + + +LLE+GERLP+P C
Sbjct 904 QSDVWSYGVTVWELMTFG--------------AKPYDGIPAREIPDLLEKGERLPQPPIC 949
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW ++ RP F L+ +
Sbjct 950 TIDVYMIMVKCWMIDSECRPRFRELVSEFSRM 981
Score = 219 bits (559), Expect = 5e-57, Method: Composition-based stats.
Identities = 68/335 (20%), Positives = 128/335 (38%), Gaps = 39/335 (12%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P +Q + + E+ ++ LG G VY+G +G
Sbjct 703 TPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENV-------------- 748
Query 630 GRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ V +KVL + + A +M+ V +++ + G+C+ +VT+
Sbjct 749 ------KIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQ 801
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ +G L +R RG + + Q+A +SYLE+ LVH ++ RN+L+
Sbjct 802 LMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPN-- 859
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+K++D G+ + I W+A E + + D W +G
Sbjct 860 -----HVKITDFGLARLLDIDETEYHADGGKVPIKWMALESIL--RRRFTHQSDVWSYGV 912
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860
T+ E+ G P E ++ RLP+P + + +C + RP FR
Sbjct 913 TVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFR 972
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895
++ + +R+ V+ N D S P
Sbjct 973 ELVSEFSRMARDPQRFVVIQNEDLGPSSPMDSTFY 1007
>sp|Q9ES74|NEK7_MOUSE Serine/threonine-protein kinase Nek7 OS=Mus
musculus OX=10090 GN=Nek7 PE=1 SV=1
Length=302
Score = 228 bits (580), Expect = 9e-66, Method: Composition-based stats.
Identities = 65/311 (21%), Positives = 119/311 (38%), Gaps = 30/311 (10%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ D + + +G G F +V Y + G VA+K
Sbjct 8 MQGPPVTQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEV----YRASCLLDGVPVALK 63
Query 931 ALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
++ + R+ +EID+L+ L H ++IKY + E L +V+E G L
Sbjct 64 KVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNE--LNIVLELADAGDLSR 121
Query 989 YLPRHS-----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
+ I + + Q+C + ++H++ +HRD+ NV + +VK+GD G
Sbjct 122 MIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLG 181
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
L + ++ +PE + E + + SD+WS G LYE+
Sbjct 182 LGRFFS---SKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYG 238
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRP-DKCPCEVYHLMKNCWETEASFRPTF 1162
+M + L + +E+ + P P D E+ L+ C + RP
Sbjct 239 -------------DKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDI 285
Query 1163 ENLIPILKTVH 1173
+ + K +H
Sbjct 286 AYVYDVAKRMH 296
Score = 171 bits (434), Expect = 4e-46, Method: Composition-based stats.
Identities = 48/299 (16%), Positives = 100/299 (33%), Gaps = 47/299 (16%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL--- 644
+G+G + VY ++G + V LK +
Sbjct 33 NFRIEKKIGRGQFSEVYRASCLLDG------------------------VPVALKKVQIF 68
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD---VWLRR 701
D + L+ Q++H ++ + + E +V E + G L ++
Sbjct 69 DLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKK 128
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
++ +P QL SAL ++ ++ ++H ++ N+ + G+ +KL D G
Sbjct 129 QKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGV-------VKLGDLG 181
Query 762 VGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+G S+ V +++PE + + D W G L E+
Sbjct 182 LGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNF--KSDIWSLGCLLYEMAALQSPFYGD 239
Query 818 RSPS----EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
+ +K + +L L + C+ +P +RP + R+
Sbjct 240 KMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHAC 298
>sp|Q9LFH9|LRK81_ARATH L-type lectin-domain containing receptor
kinase VIII.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK81 PE=2
SV=1
Length=715
Score = 240 bits (612), Expect = 9e-66, Method: Composition-based stats.
Identities = 64/279 (23%), Positives = 119/279 (43%), Gaps = 21/279 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V Y TG++VAVK + ++ + E+ I+ +L H ++++
Sbjct 382 IGHGAFGVV----YRGILPETGDIVAVKRCSHSSQDK-KNEFLSELSIIGSLRHRNLVRL 436
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLH---AQ 1017
+G C ++GE + LV + +P GSL L R ++ + +AYLH
Sbjct 437 QGWCHEKGE--ILLVYDLMPNGSLDKALFESRFTLPWDHRKKILLGVASALAYLHRECEN 494
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ + N++LD K+GDFGLA+ + + + APE L +
Sbjct 495 QVIHRDVKSSNIMLDESFNAKLGDFGLARQIEHDKSPEAT--VAAGTMGYLAPEYLLTGR 552
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFL-------ELIGIAQGQMTVLRLTELLER 1130
+DV+S+G + E+++ + L+ G +++ +
Sbjct 553 ASEKTDVFSYGAVVLEVVSGRRPIEKDLNVQRHNVGVNPNLVEWVWGLYKEGKVSAAADS 612
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ V + C + +FRPT +++ +L
Sbjct 613 RLEGKFDEGEMWRVLVVGLACSHPDPAFRPTMRSVVQML 651
Score = 218 bits (556), Expect = 2e-58, Method: Composition-based stats.
Identities = 58/265 (22%), Positives = 98/265 (37%), Gaps = 45/265 (17%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P+ + +L + K + +G G VY G L G
Sbjct 360 APKEFSYKEL---KAGTKNFNESRIIGHGAFGVVYRGILPETGD---------------- 400
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
V +K S D F S++ + H +L + G C E ++V +
Sbjct 401 --------IVAVKRCSHSSQDKKNEFLSELSIIGSLRHRNLVRLQGWCHEKGEILLVYDL 452
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLG 746
+ +G LD L R +P + + +ASAL+YL ++H +V NI+L
Sbjct 453 MPNGSLDKALFESRFTLPWDHRKKILLGVASALAYLHRECENQVIHRDVKSSNIMLDE-- 510
Query 747 LAEGTSPFIKLSDPGVGLGALSREE-----RVERIPWLAPECLPGGANSLSTAMDKWGFG 801
S KL D G+ + + +LAPE L G S D + +G
Sbjct 511 -----SFNAKLGDFGLARQIEHDKSPEATVAAGTMGYLAPEYLLTGRA--SEKTDVFSYG 563
Query 802 ATLLEICFDGEAPLQSRSPSEKEHF 826
A +LE+ G P++ ++ +
Sbjct 564 AVVLEVVS-GRRPIEKDLNVQRHNV 587
>sp|Q9FJ55|CIPKJ_ARATH CBL-interacting serine/threonine-protein
kinase 19 OS=Arabidopsis thaliana OX=3702 GN=CIPK19 PE=1 SV=1
Length=483
Score = 234 bits (596), Expect = 9e-66, Method: Composition-based stats.
Identities = 67/269 (25%), Positives = 115/269 (43%), Gaps = 26/269 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960
LG G F KV L N +GE VA+K + + + + K+EI ILR + H +I+
Sbjct 34 LGHGTFAKVYL----ARNAQSGESVAIKVIDKEKVLKSGLIAHIKREISILRRVRHPNIV 89
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ + + + VMEYV G L + + + + + QQ+ +++ H +
Sbjct 90 QLFEVMATKSK--IYFVMEYVKGGELFNKVAKGRLKEEMARKYFQQLISAVSFCHFRGVY 147
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
HRDL N+LLD + +K+ DFGL+ + + +P + APE L +
Sbjct 148 HRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPA-YVAPEVLARKGYDG 206
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
D+WS GV L+ L+ V+ + + + RG+ P
Sbjct 207 AKVDIWSCGVILFVLMAGFLPFHD---------------RNVMAMYKKIYRGD-FRCPRW 250
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPI 1168
P E+ L+ ET+ R T +++
Sbjct 251 FPVEINRLLIRMLETKPERRFTMPDIMET 279
Score = 180 bits (457), Expect = 3e-47, Method: Composition-based stats.
Identities = 57/310 (18%), Positives = 97/310 (31%), Gaps = 45/310 (15%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ LG GT VY R G V +KV+D
Sbjct 27 KYEMGRLLGHGTFAKVYLARNAQSGES------------------------VAIKVIDKE 62
Query 648 H---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ S++ +V H ++ + V + V EYV+ G L + +G
Sbjct 63 KVLKSGLIAHIKREISILRRVRHPNIVQLFEVMATKSKIYFVMEYVKGGELFN--KVAKG 120
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763
+ QQL SA+S+ + + H ++ N+LL G +K+SD G+
Sbjct 121 RLKEEMARKYFQQLISAVSFCHFRGVYHRDLKPENLLLDENG-------NLKVSDFGLSA 173
Query 764 -----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
++APE L +D W G L + G P R
Sbjct 174 VSDQIRQDGLFHTFCGTPAYVAPEVLARKGYD-GAKVDIWSCGVIL-FVLMAGFLPFHDR 231
Query 819 SPSEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
+ R R P ++ L + L +P +R + I+ +
Sbjct 232 NVMAMYKKIYRGDFRCPRWFPVEINRLLIRMLETKPERRFTMPDIMETSWFKKGFKHIKF 291
Query 878 LTVNPDSPAS 887
+ +
Sbjct 292 YVEDDHQLCN 301
>sp|Q9V6K3|ROR2_DROME Tyrosine-protein kinase transmembrane receptor
Ror2 OS=Drosophila melanogaster OX=7227 GN=Nrk PE=1 SV=2
Length=724
Score = 240 bits (613), Expect = 1e-65, Method: Composition-based stats.
Identities = 86/320 (27%), Positives = 137/320 (43%), Gaps = 32/320 (10%)
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP-T 919
TI + L + + + + + +R LG+G FG+V
Sbjct 405 TIHSNCVALTTVTNVSDAKGTKPNARLEKLEYPRGDIVYVRSLGQGAFGRVFQARAPGLV 464
Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979
D +VAVK LK D Q + +++E +L H +I++ G C + + L+ E
Sbjct 465 PDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVRLLGVCALG--RPMCLLFE 522
Query 980 YVPLGSLRDYLP--------------RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
Y+ G L ++L R + LL A I GM YL + ++HRDLA
Sbjct 523 YMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQMAANIAAGMLYLSERKFVHRDLA 582
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
RN L++ VKI DFGL+ + +YY+ E+ P+ W E + KF SDVW
Sbjct 583 TRNCLINEHMAVKIADFGLSHKIYL-QDYYKGDENDFIPIRWMPLESILYNKFSLESDVW 641
Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
++G+ L+E+ + +T + + ++ G L PD P VY
Sbjct 642 AYGICLWEVFSFALQ--------------PYFGLTHEEVIKYIKEGNVLGCPDNTPLSVY 687
Query 1146 HLMKNCWETEASFRPTFENL 1165
LM+ CW + S RP F +
Sbjct 688 ALMRRCWNRKPSERPGFAEI 707
Score = 232 bits (592), Expect = 5e-63, Method: Composition-based stats.
Identities = 68/332 (20%), Positives = 127/332 (38%), Gaps = 57/332 (17%)
Query 559 SNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618
+N+ +G + + R L + +I + LGQG V++ R
Sbjct 417 TNVSDAKGTKPNAR------LEKLEYPRGDIVYVRSLGQGAFGRVFQAR----------- 459
Query 619 GKMDDEDPLVPGRDRGQE-LRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676
PG QE L V +K+L D + + + F A L+++ H ++ + GV
Sbjct 460 ---------APGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVRLLGV 510
Query 677 CVRGPENIMVTEYVEHGPLDVWLR------------RERGHVPMAWKMVVAQQLASALSY 724
C G ++ EY+ G L +LR ++R + + +A +A+ + Y
Sbjct 511 CALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQMAANIAAGMLY 570
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPW 778
L + VH ++ RN L+ +K++D G+ ++ I W
Sbjct 571 LSERKFVHRDLATRNCLINE-------HMAVKIADFGLSHKIYLQDYYKGDENDFIPIRW 623
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEP 836
+ E + N S D W +G L E+ P + E + + + L P+
Sbjct 624 MPLESIL--YNKFSLESDVWAYGICLWEVFSFALQPYFGLTHEEVIKYIKEGNVLGCPDN 681
Query 837 SCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ + L +C +P++RP F I +
Sbjct 682 TPLSVYALMRRCWNRKPSERPGFAEINHCIQH 713
>sp|Q60553|ERBB2_MESAU Receptor tyrosine-protein kinase erbB-2
OS=Mesocricetus auratus OX=10036 GN=ERBB2 PE=2 SV=1
Length=1254
Score = 247 bits (631), Expect = 1e-65, Method: Composition-based stats.
Identities = 88/272 (32%), Positives = 133/272 (49%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + VA+K L+ + P+ E ++ L ++ +
Sbjct 726 LGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGLGSPYVSRL 785
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C +QLV + +P G L D++ H +G LL + QI +GM+YL +
Sbjct 786 LGICLTST---VQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLV 842
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W A E + +F +
Sbjct 843 HRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWIALESILRRRFTH 901
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + + +LLE+GERLP+P C
Sbjct 902 QSDVWSYGVTVWELMTFG--------------AKPYDGIPAREIPDLLEKGERLPQPPIC 947
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW ++ RP F L+ +
Sbjct 948 TIDVYMIMVKCWMIDSECRPRFRELVSEFSRM 979
Score = 218 bits (556), Expect = 1e-56, Method: Composition-based stats.
Identities = 62/316 (20%), Positives = 122/316 (39%), Gaps = 39/316 (12%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P +Q + + E+ ++ LG G VY+G +G
Sbjct 701 TPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENV-------------- 746
Query 630 GRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ V +KVL + + A +M+ + +++ + G+C+ +VT+
Sbjct 747 ------KIPVAIKVLRENTSPKANKEILDEAYVMAGLGSPYVSRLLGICLTSTVQ-LVTQ 799
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ +G L +R RG + + Q+A +SYLE+ LVH ++ RN+L+
Sbjct 800 LMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPN-- 857
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+K++D G+ + I W+A E + + D W +G
Sbjct 858 -----HVKITDFGLARLLDIDETEYHADGGKVPIKWIALESIL--RRRFTHQSDVWSYGV 910
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860
T+ E+ G P E ++ RLP+P + + +C + RP FR
Sbjct 911 TVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFR 970
Query 861 TILRDLTRLQPHNLAD 876
++ + +R+
Sbjct 971 ELVSEFSRMARDPQRF 986
>sp|Q69JN6|BRL1_ORYSJ Brassinosteroid LRR receptor kinase BRL1
OS=Oryza sativa subsp. japonica OX=39947 GN=BRL1 PE=2 SV=1
Length=1214
Score = 247 bits (630), Expect = 1e-65, Method: Composition-based stats.
Identities = 71/295 (24%), Positives = 124/295 (42%), Gaps = 22/295 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG+V G +VA+K L G R + E++ + + H +++
Sbjct 918 IGSGGFGEVYKAKLK-----DGSVVAIKKLIHFTGQGDRE-FTAEMETIGKIKHRNLVPL 971
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHAQ 1017
G C+ E+ LV EY+ GSL L + + A G+A+LH
Sbjct 972 LGYCKIGDER--LLVYEYMKHGSLDVVLHDKAKASVKLDWSARKKIAIGSARGLAFLHHS 1029
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H IHRD+ + NVLLDN+ ++ DFG+A+ + + V +P + PE +
Sbjct 1030 CIPHIIHRDMKSSNVLLDNNLDARVSDFGMARLMNALDTHLSVSTLAGTP-GYVPPEYYQ 1088
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
++ DV+S+GV L ELL+ L+G + + R +E+ +
Sbjct 1089 SFRCTTKGDVYSYGVVLLELLSGKKPIDPTEFGDNNLVGWVKQMVKENRSSEIFDPTLTD 1148
Query 1135 PRPDKCPCEVYH---LMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
+ + E+Y + C + + RPT ++ + K + FS+
Sbjct 1149 RKSGEA--ELYQYLKIACECLDDRPNRRPTMIQVMAMFKELQLDSDSDILDGFSI 1201
Score = 211 bits (538), Expect = 2e-54, Method: Composition-based stats.
Identities = 60/326 (18%), Positives = 116/326 (36%), Gaps = 65/326 (20%)
Query 576 LSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L +L+F + + + +G G VY+ +L+
Sbjct 897 LRKLTFAHLLEATNGFSAETLIGSGGFGEVYKAKLKDGS--------------------- 935
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
V +K L F + ++ H +L + G C G E ++V EY++HG
Sbjct 936 ----VVAIKKLIHFTGQGDREFTAEMETIGKIKHRNLVPLLGYCKIGDERLLVYEYMKHG 991
Query 694 PLDVWLRRERG---HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGL 747
LDV L + + + + +A A L++L + +++H ++ N+LL
Sbjct 992 SLDVVLHDKAKASVKLDWSARKKIAIGSARGLAFLHHSCIPHIIHRDMKSSNVLLDN--- 1048
Query 748 AEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
+ ++SD G+ LS ++ PE + +T D + +G
Sbjct 1049 ----NLDARVSDFGMARLMNALDTHLSVSTLAGTPGYVPPEYYQ--SFRCTTKGDVYSYG 1102
Query 802 ATLLEICFDGEA--PLQSRSPSEK--EHFYQRQHRLPEPSCPQLAT-------------L 844
LLE+ + P + + +++R E P L +
Sbjct 1103 VVLLELLSGKKPIDPTEFGDNNLVGWVKQMVKENRSSEIFDPTLTDRKSGEAELYQYLKI 1162
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQ 870
+CL P +RP+ ++ LQ
Sbjct 1163 ACECLDDRPNRRPTMIQVMAMFKELQ 1188
>sp|O02466|ILPR_BRALA Insulin-like peptide receptor OS=Branchiostoma
lanceolatum OX=7740 PE=2 SV=1
Length=1363
Score = 247 bits (631), Expect = 1e-65, Method: Composition-based stats.
Identities = 97/337 (29%), Positives = 150/337 (45%), Gaps = 47/337 (14%)
Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923
+ + ++ + D D + + IR+LG+G FG V
Sbjct 961 QMPNGVLYASVNPEYMSSDDVYVPDEWEVPREKITLIRELGQGSFGMVYEGEAKDVVKDE 1020
Query 924 GEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982
+ VAVK + + R + E +++T H++K G +G+ +L +VME +
Sbjct 1021 PMVSVAVKTVNESASIRERIEFLNEASVMKTFNCHHVVKLMGVV-SKGQPTL-VVMELMA 1078
Query 983 LGSLRDYLPRHSIGLA-----------------------------QLLLFAQQICEGMAY 1013
LG L++YL RH ++ A I +GM+Y
Sbjct 1079 LGDLKNYLRRHRPEEDVGLSDSPASNEAKNSPFAENDNDLPPTFKDIIQMAGVIADGMSY 1138
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
L A+ ++HRDLA RN ++ DR VKIGDFG+ + + E +YYR G PV W +PE L
Sbjct 1139 LAAKKFVHRDLACRNCMVAQDRTVKIGDFGMTRDIYE-TDYYRKGGKGLLPVRWMSPESL 1197
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
K F SDVWS+GV L+E+ T L + + + + G
Sbjct 1198 KVGVFTSQSDVWSYGVVLWEMAT--------------LASQPYQGKSNEEVLKFVIDGGM 1243
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
L +P+ CP ++Y LMK CW+ S RPTF ++ IL
Sbjct 1244 LEKPEGCPNKLYDLMKLCWQYRQSMRPTFLEIVEILS 1280
Score = 233 bits (593), Expect = 5e-61, Method: Composition-based stats.
Identities = 82/390 (21%), Positives = 143/390 (37%), Gaps = 67/390 (17%)
Query 536 CLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQL---SFHRVDQKEITQL 592
LL F + C + G+ + A +P ++ + V +++IT +
Sbjct 938 SLLLILAVIFGIWYCTKKRFGDKQMPNGVLYASVNPEYMSSDDVYVPDEWEVPREKITLI 997
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH-DI 651
LGQG+ VYEG + +P + V +K ++ S
Sbjct 998 RELGQGSFGMVYEGEAKDVVKDEPM-------------------VSVAVKTVNESASIRE 1038
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH------ 705
+ F AS+M + H+ + GV +G ++V E + G L +LRR R
Sbjct 1039 RIEFLNEASVMKTFNCHHVVKLMGVVSKGQPTLVVMELMALGDLKNYLRRHRPEEDVGLS 1098
Query 706 -------------------VPMAWK--MVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+P +K + +A +A +SYL K VH ++ RN ++A+
Sbjct 1099 DSPASNEAKNSPFAENDNDLPPTFKDIIQMAGVIADGMSYLAAKKFVHRDLACRNCMVAQ 1158
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKW 798
+K+ D G+ + + + W++PE L G ++ D W
Sbjct 1159 -------DRTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKVGV--FTSQSDVW 1209
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856
+G L E+ P Q +S E F L PE +L L C Y + R
Sbjct 1210 SYGVVLWEMATLASQPYQGKSNEEVLKFVIDGGMLEKPEGCPNKLYDLMKLCWQYRQSMR 1269
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
P+F I+ L+ + +V +
Sbjct 1270 PTFLEIVEILSPELQAHFNEVSFYHSLDNH 1299
>sp|Q9SXB5|Y1135_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g11303 OS=Arabidopsis thaliana OX=3702
GN=At1g11303 PE=3 SV=1
Length=820
Score = 242 bits (618), Expect = 1e-65, Method: Composition-based stats.
Identities = 75/278 (27%), Positives = 115/278 (41%), Gaps = 22/278 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG+G FG V G+ +AVK L G Q E+ ++ L H +++
Sbjct 513 NKLGQGGFGPVYKGMLLE-----GQEIAVKRLSQASG-QGLEELVTEVVVISKLQHRNLV 566
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA 1016
K GCC E+ LV E++P SL Y+ + IC G+ YLH
Sbjct 567 KLFGCCIAGEER--MLVYEFMPKKSLDFYIFDPREAKLLDWNTRFEIINGICRGLLYLHR 624
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRDL A N+LLD + + KI DFGLA+ P + R + APE
Sbjct 625 DSRLRIIHRDLKASNILLDENLIPKISDFGLARIFPGNEDEANTRR-VVGTYGYMAPEYA 683
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
F SDV+S GV L E+++ +S S L+ + +++
Sbjct 684 MGGLFSEKSDVFSLGVILLEIISGRRNSHST------LLAHVWSIWNEGEINGMVDPEIF 737
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+K + H+ C + A+ RP+ + +L +
Sbjct 738 DQLFEKEIRKCVHIALLCVQDAANDRPSVSTVCMMLSS 775
Score = 232 bits (591), Expect = 3e-62, Method: Composition-based stats.
Identities = 72/389 (19%), Positives = 122/389 (31%), Gaps = 63/389 (16%)
Query 501 RLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGE--- 557
RL + QD +L G S+ + C+L A R E
Sbjct 423 RLAHSEFKTQDRRPILIGT-----SLAGGIFVVATCVLLARRIVMKKRAKKKGTDAEQIF 477
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
+ G+R + L L + + + LGQG VY+G L
Sbjct 478 KRVEALAGGSREKLKELPLFEFQVLATATDNFSLSNKLGQGGFGPVYKGMLLEGQ----- 532
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
+ +K L + ++S++ H +L + G C
Sbjct 533 --------------------EIAVKRLSQASGQGLEELVTEVVVISKLQHRNLVKLFGCC 572
Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVH 732
+ G E ++V E++ LD ++ R + W + + + L YL ++H
Sbjct 573 IAGEERMLVYEFMPKKSLDFYIFDPREAKLLDWNTRFEIINGICRGLLYLHRDSRLRIIH 632
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPG 786
++ NILL + K+SD G+ + V ++APE G
Sbjct 633 RDLKASNILLDE-------NLIPKISDFGLARIFPGNEDEANTRRVVGTYGYMAPEYAMG 685
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPL-------QSRSPSEKEHFYQRQH---RLPEP 836
G S D + G LLEI S + + +L E
Sbjct 686 GL--FSEKSDVFSLGVILLEIISGRRNSHSTLLAHVWSIWNEGEINGMVDPEIFDQLFEK 743
Query 837 SCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ + C+ RPS T+
Sbjct 744 EIRKCVHIALLCVQDAANDRPSVSTVCMM 772
>sp|Q40541|NPK1_TOBAC Mitogen-activated protein kinase kinase
kinase NPK1 OS=Nicotiana tabacum OX=4097 GN=NPK1 PE=1 SV=1
Length=690
Score = 239 bits (611), Expect = 1e-65, Method: Composition-based stats.
Identities = 71/283 (25%), Positives = 129/283 (46%), Gaps = 28/283 (10%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-------ADCGPQHRSGWK 945
+K +G G FG+V + N +GE++A+K + + H +
Sbjct 76 PPIRWRKGEMIGCGAFGRVYMGM----NVDSGELLAIKEVSIAMNGASRERAQAHVRELE 131
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFA 1004
+E+++L+ L H +I++Y G + G SL +++E+VP GS+ L + S + + ++
Sbjct 132 EEVNLLKNLSHPNIVRYLGTAREAG--SLNILLEFVPGGSISSLLGKFGSFPESVIRMYT 189
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+Q+ G+ YLH +HRD+ N+L+DN +K+ DFG +K V E + +P
Sbjct 190 KQLLLGLEYLHKNGIMHRDIKGANILVDNKGCIKLADFGASKKVVELATMTGAKSMKGTP 249
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+W APE + + +++D+WS G T+ E+ T +Q V L
Sbjct 250 -YWMAPEVILQTGHSFSADIWSVGCTIIEMATGKPP-------------WSQQYQEVAAL 295
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ P P+ E + C + E R + NL+
Sbjct 296 FHIGTTKSHPPIPEHLSAESKDFLLKCLQKEPHLRHSASNLLQ 338
Score = 193 bits (491), Expect = 4e-50, Method: Composition-based stats.
Identities = 59/317 (19%), Positives = 102/317 (32%), Gaps = 39/317 (12%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
+ +G G VY G G +E+ + +
Sbjct 81 RKGEMIGCGAFGRVYMGMNVDSGELLAI-----------------KEVSIAMNGASRERA 123
Query 650 DIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
E +L+ +SH ++ G ++ E+V G + L + G P
Sbjct 124 QAHVRELEEEVNLLKNLSHPNIVRYLGTAREAGSLNILLEFVPGGSISSLL-GKFGSFPE 182
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ + +QL L YL ++H ++ G NIL+ G IKL+D G +
Sbjct 183 SVIRMYTKQLLLGLEYLHKNGIMHRDIKGANILVDNKG-------CIKLADFGASKKVVE 235
Query 769 REERV------ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
W+APE + +S S D W G T++E+ G+ P +
Sbjct 236 LATMTGAKSMKGTPYWMAPEVILQTGHSFS--ADIWSVGCTIIEMA-TGKPPWSQQYQEV 292
Query 823 KEHFYQ----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
F+ +PE + +CL EP R S +L+ H A
Sbjct 293 AALFHIGTTKSHPPIPEHLSAESKDFLLKCLQKEPHLRHSASNLLQHPFVTAEHQEARPF 352
Query 879 TVNPDSPASDPTVFHKR 895
+ + +
Sbjct 353 LRSSFMGNPENMAAQRM 369
>sp|Q9S9M3|WAKLC_ARATH Wall-associated receptor kinase-like 3
OS=Arabidopsis thaliana OX=3702 GN=WAKL3 PE=2 SV=2
Length=730
Score = 240 bits (613), Expect = 1e-65, Method: Composition-based stats.
Identities = 72/279 (26%), Positives = 116/279 (42%), Gaps = 20/279 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G G V G +VAVK K + EI +L + H +I+K
Sbjct 434 LGQGGQGTVYKRML-----VDGSIVAVKRSKV-VDEDKMEEFINEIVLLSQINHRNIVKL 487
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGMAYLHAQ- 1017
GCC + E + LV EY+P G L L + + L A +I ++Y+H+
Sbjct 488 LGCCLE-TEVPI-LVYEYIPNGDLFKRLHDEYDDYMMTWEVRLRIAVEIAGALSYMHSAA 545
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
HRD+ N+LLD KI DFG +++V + + + PE
Sbjct 546 SFPIFHRDIKTTNILLDEKYRAKISDFGTSRSVATDQTH--LTTLVAGTFGYMDPEYFLS 603
Query 1076 YKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
++ + SDV+SFGV L EL+T S+ + + L M R ++++ R+
Sbjct 604 SQYTHKSDVYSFGVVLVELITGEKPMSRVRSEEGIGLATYFLEAMKENRAVDIID--IRI 661
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
K V L + C + + RP + L+ +
Sbjct 662 KDESKQVMAVAKLARRCLNRKGNKRPNMREVSIKLERIR 700
Score = 223 bits (568), Expect = 7e-60, Method: Composition-based stats.
Identities = 63/341 (18%), Positives = 114/341 (33%), Gaps = 61/341 (18%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ LGQG + VY+ L V +K
Sbjct 424 ATDNFSIDRVLGQGGQGTVYKRMLVDGSI-------------------------VAVKRS 458
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D F L+SQ++H ++ + G C+ I+V EY+ +G L L E
Sbjct 459 KVVDEDKMEEFINEIVLLSQINHRNIVKLLGCCLETEVPILVYEYIPNGDLFKRLHDEYD 518
Query 705 HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
M W ++ +A ++A ALSY+ + + H ++ NILL A K+SD
Sbjct 519 DYMMTWEVRLRIAVEIAGALSYMHSAASFPIFHRDIKTTNILLDEKYRA-------KISD 571
Query 760 PGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G + + ++ PE ++ + D + FG L+E+ GE P
Sbjct 572 FGTSRSVATDQTHLTTLVAGTFGYMDPEYFL--SSQYTHKSDVYSFGVVLVELI-TGEKP 628
Query 815 LQSRSPSE----------------KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPS 858
+ E + + +A L +CL + +RP+
Sbjct 629 MSRVRSEEGIGLATYFLEAMKENRAVDIIDIRIKDESKQVMAVAKLARRCLNRKGNKRPN 688
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899
R + L R++ + + + + +
Sbjct 689 MREVSIKLERIRSSPKDLDVHTENEEEEEEDQLMEINRIYD 729
>sp|Q63796|M3K12_RAT Mitogen-activated protein kinase kinase kinase
12 OS=Rattus norvegicus OX=10116 GN=Map3k12 PE=1 SV=1
Length=888
Score = 243 bits (621), Expect = 1e-65, Method: Composition-based stats.
Identities = 81/301 (27%), Positives = 122/301 (41%), Gaps = 35/301 (12%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ + D + ++ +G G G V L + GE VAVK
Sbjct 132 WTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFH------GEEVAVK 185
Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
++ I LR L H +II +KG C ++ME+ G L + L
Sbjct 186 KVRDLKETD--------IKHLRKLKHPNIITFKGVCTQA--PCYCILMEFCAQGQLYEVL 235
Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
+ + L+ ++ I GM YLH IHRDL + N+L+ D +VKI DFG +K +
Sbjct 236 RAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELS 295
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
+ + V W APE ++ D+WSFGV L+ELLT P K +
Sbjct 296 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG-----EIPYKDV 346
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ I G + LP P CP L++ CW + RP+F ++ L
Sbjct 347 DSSAIIWGVGSN---------SLHLPVPSSCPDGFKILLRQCWNRKPRNRPSFRQILLHL 397
Query 1170 K 1170
Sbjct 398 D 398
Score = 202 bits (515), Expect = 3e-52, Method: Composition-based stats.
Identities = 67/305 (22%), Positives = 109/305 (36%), Gaps = 50/305 (16%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+A Q V +EI L +G G + V+ G
Sbjct 136 GKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLG-------------------- 175
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
R G+E+ V KV D D + ++ H ++ GVC + P ++
Sbjct 176 ----RFHGEEVAVK-KVRDLKETD--------IKHLRKLKHPNIITFKGVCTQAPCYCIL 222
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
E+ G L LR R P + + + +A ++YL ++H ++ N+L+
Sbjct 223 MEFCAQGQLYEVLRAGRPVTP-SLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLIT--- 278
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+K+SD G + ++ + W+APE + +S +D W FG
Sbjct 279 ----YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 332
Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
L E+ GE P + S +P L QC +P RPSFR
Sbjct 333 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNRKPRNRPSFR 391
Query 861 TILRD 865
IL
Sbjct 392 QILLH 396
>sp|Q8TDX7|NEK7_HUMAN Serine/threonine-protein kinase Nek7 OS=Homo
sapiens OX=9606 GN=NEK7 PE=1 SV=1
Length=302
Score = 227 bits (579), Expect = 1e-65, Method: Composition-based stats.
Identities = 65/311 (21%), Positives = 118/311 (38%), Gaps = 30/311 (10%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ D + + +G G F +V Y G VA+K
Sbjct 8 MQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEV----YRAACLLDGVPVALK 63
Query 931 ALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
++ + R+ +EID+L+ L H ++IKY + E L +V+E G L
Sbjct 64 KVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNE--LNIVLELADAGDLSR 121
Query 989 YLPRHS-----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
+ I + + Q+C + ++H++ +HRD+ NV + +VK+GD G
Sbjct 122 MIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLG 181
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
L + ++ +PE + E + + SD+WS G LYE+
Sbjct 182 LGRFFS---SKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYG 238
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRP-DKCPCEVYHLMKNCWETEASFRPTF 1162
+M + L + +E+ + P P D E+ L+ C + RP
Sbjct 239 -------------DKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDV 285
Query 1163 ENLIPILKTVH 1173
+ + K +H
Sbjct 286 TYVYDVAKRMH 296
Score = 173 bits (438), Expect = 1e-46, Method: Composition-based stats.
Identities = 48/299 (16%), Positives = 100/299 (33%), Gaps = 47/299 (16%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL--- 644
+G+G + VY ++G + V LK +
Sbjct 33 NFRIEKKIGRGQFSEVYRAACLLDG------------------------VPVALKKVQIF 68
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD---VWLRR 701
D + L+ Q++H ++ + + E +V E + G L ++
Sbjct 69 DLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKK 128
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
++ +P QL SAL ++ ++ ++H ++ N+ + G+ +KL D G
Sbjct 129 QKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGV-------VKLGDLG 181
Query 762 VGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+G S+ V +++PE + + D W G L E+
Sbjct 182 LGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNF--KSDIWSLGCLLYEMAALQSPFYGD 239
Query 818 RSPS----EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
+ +K + +L L + C+ +P +RP + R+
Sbjct 240 KMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHAC 298
>sp|O65440|BAME3_ARATH Leucine-rich repeat receptor-like serine/threonine-protein
kinase BAM3 OS=Arabidopsis thaliana OX=3702
GN=BAM3 PE=1 SV=3
Length=992
Score = 244 bits (624), Expect = 1e-65, Method: Composition-based stats.
Identities = 74/319 (23%), Positives = 133/319 (42%), Gaps = 23/319 (7%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-K 933
++ + + +K+ +G+G G V GE VAVK L
Sbjct 688 PNLWKLIGFQKLGFRSEHILECVKENHVIGKGGRGIVYKGV-----MPNGEEVAVKKLLT 742
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993
G H +G EI L + H +I++ C ++ LV EY+P GSL + L
Sbjct 743 ITKGSSHDNGLAAEIQTLGRIRHRNIVRLLAFCSNKDVN--LLVYEYMPNGSLGEVLHGK 800
Query 994 S---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
+ + L A + +G+ YLH IHRD+ + N+LL + + DFGLAK
Sbjct 801 AGVFLKWETRLQIALEAAKGLCYLHHDCSPLIIHRDVKSNNILLGPEFEAHVADFGLAKF 860
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ + + + APE + SDV+SFGV L EL+T + +
Sbjct 861 MMQDNGASECMSSIAGSYGYIAPEYAYTLRIDEKSDVYSFGVVLLELITGRKPVDNFGEE 920
Query 1108 FLELIGIAQGQMTVLR--LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
++++ ++ Q R + +++++ P E++ + C + + RPT +
Sbjct 921 GIDIVQWSKIQTNCNRQGVVKIIDQRLSN-IPLAEAMELFFVAMLCVQEHSVERPTMREV 979
Query 1166 IPILKTVHEKYQGQAPSVF 1184
+ ++ Q + P+ F
Sbjct 980 VQMIS------QAKQPNTF 992
Score = 189 bits (480), Expect = 1e-47, Method: Composition-based stats.
Identities = 54/280 (19%), Positives = 94/280 (34%), Gaps = 53/280 (19%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---- 644
+ + +G+G R VY+G + V +K L
Sbjct 710 VKENHVIGKGGRGIVYKGVMPNGE-------------------------EVAVKKLLTIT 744
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
S HD LA + ++ H ++ + C N++V EY+ +G L L + G
Sbjct 745 KGSSHDNGLA--AEIQTLGRIRHRNIVRLLAFCSNKDVNLLVYEYMPNGSLGEVLHGKAG 802
Query 705 -HVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ ++ +A + A L YL + ++H +V NILL G ++D
Sbjct 803 VFLKWETRLQIALEAAKGLCYLHHDCSPLIIHRDVKSNNILL-------GPEFEAHVADF 855
Query 761 GVGLGALSR-------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ + ++APE + D + FG LLE+ G
Sbjct 856 GLAKFMMQDNGASECMSSIAGSYGYIAPEYA--YTLRIDEKSDVYSFGVVLLELI-TGRK 912
Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEP 853
P E Q + + + Q L+ P
Sbjct 913 P-VDNFGEEGIDIVQWSKIQTNCNRQGVVKIIDQRLSNIP 951
>sp|O22476|BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 OS=Arabidopsis
thaliana OX=3702 GN=BRI1 PE=1 SV=1
Length=1196
Score = 246 bits (629), Expect = 1e-65, Method: Composition-based stats.
Identities = 74/287 (26%), Positives = 122/287 (43%), Gaps = 20/287 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+G G FG V G VA+K L G R + E++ + + H
Sbjct 883 FHNDSLIGSGGFGDVYKAILK-----DGSAVAIKKLIHVSGQGDRE-FMAEMETIGKIKH 936
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGM 1011
+++ G C+ E+ LV E++ GSL D L + + A G+
Sbjct 937 RNLVPLLGYCKVGDER--LLVYEFMKYGSLEDVLHDPKKAGVKLNWSTRRKIAIGSARGL 994
Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
A+LH H IHRD+ + NVLLD + ++ DFG+A+ + + V +P +
Sbjct 995 AFLHHNCSPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTP-GYV 1053
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE + ++ DV+S+GV L ELLT + SP L+G + Q LR++++
Sbjct 1054 PPEYYQSFRCSTKGDVYSYGVVLLELLTGKRPTDSPDFGDNNLVGWVK-QHAKLRISDVF 1112
Query 1129 ERGERLPRPDKCPCEVYHL--MKNCWETEASFRPTFENLIPILKTVH 1173
+ P + HL C + A RPT ++ + K +
Sbjct 1113 DPELMKEDPALEIELLQHLKVAVACLDDRAWRRPTMVQVMAMFKEIQ 1159
Score = 213 bits (542), Expect = 6e-55, Method: Composition-based stats.
Identities = 57/370 (15%), Positives = 120/370 (32%), Gaps = 60/370 (16%)
Query 576 LSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L +L+F + S +G G +VY+ L+
Sbjct 868 LRKLTFADLLQATNGFHNDSLIGSGGFGDVYKAILKDGS--------------------- 906
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
V +K L F + ++ H +L + G C G E ++V E++++G
Sbjct 907 ----AVAIKKLIHVSGQGDREFMAEMETIGKIKHRNLVPLLGYCKVGDERLLVYEFMKYG 962
Query 694 PLDVWLRRERG---HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGL 747
L+ L + + + + +A A L++L + +++H ++ N+LL
Sbjct 963 SLEDVLHDPKKAGVKLNWSTRRKIAIGSARGLAFLHHNCSPHIIHRDMKSSNVLLDE--- 1019
Query 748 AEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
+ ++SD G+ LS ++ PE + ST D + +G
Sbjct 1020 ----NLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQ--SFRCSTKGDVYSYG 1073
Query 802 ATLLEICFDGEA---PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT-QRP 857
LLE+ P + + R+ + P+L +P +
Sbjct 1074 VVLLELLTGKRPTDSPDFGDNNLVGWVKQHAKLRISDVFDPELMK-------EDPALEIE 1126
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI-RDLGEGHFGKVSLYCY 916
+ + + L V + + + R + +G F + +
Sbjct 1127 LLQHLKVAVACLDDRAWRRPTMVQVMAMFKEIQAGSGIDSQSTIRSIEDGGFSTIEMVDM 1186
Query 917 DPTNDGTGEM 926
G++
Sbjct 1187 SIKEVPEGKL 1196
>sp|D3ZBE5|NEK7_RAT Serine/threonine-protein kinase Nek7 OS=Rattus
norvegicus OX=10116 GN=Nek7 PE=1 SV=1
Length=302
Score = 227 bits (579), Expect = 1e-65, Method: Composition-based stats.
Identities = 65/311 (21%), Positives = 119/311 (38%), Gaps = 30/311 (10%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ D + + +G G F +V Y + G VA+K
Sbjct 8 MQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEV----YRASCLLDGVPVALK 63
Query 931 ALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
++ + R+ +EID+L+ L H ++IKY + E L +V+E G L
Sbjct 64 KVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNE--LNIVLELADAGDLSR 121
Query 989 YLPRHS-----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
+ I + + Q+C + ++H++ +HRD+ NV + +VK+GD G
Sbjct 122 MIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLG 181
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
L + ++ +PE + E + + SD+WS G LYE+
Sbjct 182 LGRFFS---SKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYG 238
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRP-DKCPCEVYHLMKNCWETEASFRPTF 1162
+M + L + +E+ + P P D E+ L+ C + RP
Sbjct 239 -------------DKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDI 285
Query 1163 ENLIPILKTVH 1173
+ + K +H
Sbjct 286 AYVYDVAKRMH 296
Score = 171 bits (433), Expect = 6e-46, Method: Composition-based stats.
Identities = 48/299 (16%), Positives = 100/299 (33%), Gaps = 47/299 (16%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL--- 644
+G+G + VY ++G + V LK +
Sbjct 33 NFRIEKKIGRGQFSEVYRASCLLDG------------------------VPVALKKVQIF 68
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD---VWLRR 701
D + L+ Q++H ++ + + E +V E + G L ++
Sbjct 69 DLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKK 128
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
++ +P QL SAL ++ ++ ++H ++ N+ + G+ +KL D G
Sbjct 129 QKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGV-------VKLGDLG 181
Query 762 VGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+G S+ V +++PE + + D W G L E+
Sbjct 182 LGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNF--KSDIWSLGCLLYEMAALQSPFYGD 239
Query 818 RSPS----EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
+ +K + +L L + C+ +P +RP + R+
Sbjct 240 KMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHAC 298
>sp|Q5MD89|VGFR3_DANRE Vascular endothelial growth factor receptor
3 OS=Danio rerio OX=7955 GN=flt4 PE=2 SV=1
Length=1357
Score = 247 bits (631), Expect = 1e-65, Method: Composition-based stats.
Identities = 89/361 (25%), Positives = 142/361 (39%), Gaps = 69/361 (19%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG-EMV 927
+ P + S + L+ + LG G FGKV + + V
Sbjct 838 MDPGEVPLEEQCEYLPYDSSQWEISRDRLRLGKVLGHGAFGKVIEASIFGHDKKSSANTV 897
Query 928 AVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
AVK LK E+ IL + H +++ G C + +V EY G+L
Sbjct 898 AVKMLKEGATASEHKALMSELKILIHIGNHLNVVNLLGACTKPNGPLMVIV-EYCKYGNL 956
Query 987 RDYLP----------------------------------------------------RHS 994
++L +
Sbjct 957 SNFLRAKREFFLPYRDRSPKTQSQVRRMIEAGQASQSEHQPSTSSTNPPRVTVDDLWKTP 1016
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ + L+ ++ Q+ GM +L ++ IHRDLAARN+LL + +VKI DFGLA+ + + +Y
Sbjct 1017 LTIEDLICYSFQVARGMEFLASRKCIHRDLAARNILLSENNVVKICDFGLARDIYKDPDY 1076
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
R + + P+ W APE + + + SDVWSFGV L+E+ + S
Sbjct 1077 VR-KGNARLPLKWMAPESIFDKVYTSQSDVWSFGVLLWEIFSLGASPY------------ 1123
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
G + L+ G R+ PD E+Y +M CW+ E RPTF L+ IL + +
Sbjct 1124 -PGIQIDEDFCKRLKDGTRMRAPDNASPEIYGIMLACWQGEPRERPTFPALVEILGDLLQ 1182
Query 1175 K 1175
+
Sbjct 1183 E 1183
Score = 212 bits (540), Expect = 1e-54, Method: Composition-based stats.
Identities = 61/366 (17%), Positives = 119/366 (33%), Gaps = 90/366 (25%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
S + + + LG G V E + +
Sbjct 855 DSSQWEISRDRLRLGKVLGHGAFGKVIEASIFGHDK-------------------KSSAN 895
Query 638 RVVLKVLDPS-HHDIALAFYETASLMSQV-SHTHLAFVHGVCVRG-PENIMVTEYVEHGP 694
V +K+L A ++ + +H ++ + G C + +++ EY ++G
Sbjct 896 TVAVKMLKEGATASEHKALMSELKILIHIGNHLNVVNLLGACTKPNGPLMVIVEYCKYGN 955
Query 695 LDVWLRRER--------------------------------------------------G 704
L +LR +R
Sbjct 956 LSNFLRAKREFFLPYRDRSPKTQSQVRRMIEAGQASQSEHQPSTSSTNPPRVTVDDLWKT 1015
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + + + Q+A + +L ++ +H ++ RNILL+ + +K+ D G+
Sbjct 1016 PLTIEDLICYSFQVARGMEFLASRKCIHRDLAARNILLSENNV-------VKICDFGLAR 1068
Query 765 GALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + + W+APE + ++ D W FG L EI G +P
Sbjct 1069 DIYKDPDYVRKGNARLPLKWMAPESIFDKV--YTSQSDVWSFGVLLWEIFSLGASPYPGI 1126
Query 819 SPSE---KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
E K + R P+ + P++ + C EP +RP+F ++ L L N
Sbjct 1127 QIDEDFCKRLKDGTRMRAPDNASPEIYGIMLACWQGEPRERPTFPALVEILGDLLQENSL 1186
Query 876 DVLTVN 881
+ N
Sbjct 1187 PEIPFN 1192
>sp|Q99JT2|STK26_MOUSE Serine/threonine-protein kinase 26 OS=Mus
musculus OX=10090 GN=Stk26 PE=1 SV=1
Length=416
Score = 231 bits (590), Expect = 1e-65, Method: Composition-based stats.
Identities = 72/294 (24%), Positives = 123/294 (42%), Gaps = 24/294 (8%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933
+A + + K+ +G+G FG+V + ++ T ++VA+K +
Sbjct 1 MAHSPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEV----FKGIDNRTQQVVAIKIID 56
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993
+ +QEI +L ++ KY G + L ++MEY+ GS D L
Sbjct 57 LEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSK--LWIIMEYLGGGSALDLLRAG 114
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
Q+ ++I +G+ YLH++ IHRD+ A NVLL VK+ DFG+A + +
Sbjct 115 PFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD--- 171
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
R FW APE +++ + +D+WS G+T EL + PP
Sbjct 172 TQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIEL-----AKGEPP-------- 218
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
M +R+ L+ + + C + SFRPT + L+
Sbjct 219 --NSDMHPMRVLFLIPKNNPPTLIGDFTKSFKEFIDACLNKDPSFRPTAKELLK 270
Score = 209 bits (532), Expect = 6e-58, Method: Composition-based stats.
Identities = 61/310 (20%), Positives = 119/310 (38%), Gaps = 44/310 (14%)
Query 570 SPRTLNLSQLSFHRVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
SP + + + + D +E T+L +G+G+ V++G
Sbjct 4 SPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGI--------------------- 42
Query 629 PGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
D + V +K++D D + +++SQ +++ +G ++G + ++
Sbjct 43 ---DNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIM 99
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
EY+ G LR G + +++ L YL ++ +H ++ N+LL+ G
Sbjct 100 EYLGGGSALDLLRA--GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGD 157
Query 748 AEGTSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+KL+D GV + R V W+APE + A + D W G T
Sbjct 158 -------VKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSA--YDSKADIWSLGIT 208
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861
+E+ GE P P + + L CL +P+ RP+ +
Sbjct 209 AIELA-KGEPPNSDMHPMRVLFLIPKNNPPTLIGDFTKSFKEFIDACLNKDPSFRPTAKE 267
Query 862 ILRDLTRLQP 871
+L+ ++
Sbjct 268 LLKHKFIVKN 277
>sp|Q86HG9|Y9871_DICDI Probable serine/threonine-protein kinase
DDB_G0271682 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0271682
PE=3 SV=2
Length=1024
Score = 245 bits (625), Expect = 1e-65, Method: Composition-based stats.
Identities = 77/280 (28%), Positives = 125/280 (45%), Gaps = 38/280 (14%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G G+V Y + G VAVK + K+ + +++E+ IL+ L H +++
Sbjct 365 KIGSGACGEVCQYEWK------GTPVAVKTIFKSLLRKDKKEEFEKEVSILKCLRHPNVV 418
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH-- 1015
+ G C G +L ++ EY+ GSLRD L + + L+ + + +GM YLH
Sbjct 419 LFMGTCLLNG--NLAIITEYLNRGSLRDVLTTMNKSELSLSVKVKMLIDVAQGMNYLHTY 476
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ IHRDL + N+L+DN+ VK+ DFGL++ + G + + W APE
Sbjct 477 SPPIIHRDLKSLNLLVDNNFNVKVSDFGLSRFISGGIG--SSAKTFCGTLSWIAPEVFNG 534
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ DV+SFG+ L+E+LTH S + L
Sbjct 535 SGYTTKVDVYSFGIVLWEILTHKQPSGNISATSL----------------------GHPE 572
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
P CP L+K C RP F ++ LK ++ +
Sbjct 573 LPSNCPQSFSDLIKECCNRNPDQRPNFSQILLKLKLMYNQ 612
Score = 202 bits (513), Expect = 1e-51, Method: Composition-based stats.
Identities = 60/315 (19%), Positives = 115/315 (37%), Gaps = 51/315 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ + E+ + +G G V + + V +K
Sbjct 355 IQENELLFIKKIGSGACGEVCQYEWKG--------------------------TPVAVKT 388
Query 644 LDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL-R 700
+ S D F + S++ + H ++ G C+ ++TEY+ G L L
Sbjct 389 IFKSLLRKDKKEEFEKEVSILKCLRHPNVVLFMGTCLLNGNLAIITEYLNRGSLRDVLTT 448
Query 701 RERGHVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ + ++ K+ + +A ++YL + ++H ++ N+L+ + +K+S
Sbjct 449 MNKSELSLSVKVKMLIDVAQGMNYLHTYSPPIIHRDLKSLNLLVDN-------NFNVKVS 501
Query 759 DPGVGLGA-----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
D G+ S + + W+APE G + +T +D + FG L EI +
Sbjct 502 DFGLSRFISGGIGSSAKTFCGTLSWIAPEVFNG--SGYTTKVDVYSFGIVLWEILTH-KQ 558
Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
P + S + H LP + L +C P QRP+F IL L +
Sbjct 559 PSGNISATSLGH-----PELPSNCPQSFSDLIKECCNRNPDQRPNFSQILLKLKLMYNQI 613
Query 874 LADVLTVNPDSPASD 888
+ DS +
Sbjct 614 NNNNNNNKIDSSSFH 628
Score = 84.7 bits (208), Expect = 4e-15, Method: Composition-based stats.
Identities = 29/143 (20%), Positives = 60/143 (42%), Gaps = 12/143 (8%)
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
N+ N+ +K+ DFGL++ + +E ++ + PE L + SD++S
Sbjct 885 NI---NEIKIKVHDFGLSRFNTQENE--ESLKEIKGNFLYSPPELLSLNTYSNKSDIYSL 939
Query 1088 GVTLYELL-THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
+ LYEL T + P + L + + + R + P E+
Sbjct 940 SIVLYELFETCLTKTYKKPYHEVTL------DFDFQIIHKTSKLNLRPTISNNMPNEISK 993
Query 1147 LMKNCWETEASFRPTFENLIPIL 1169
+++ W +++ RP+ + +I L
Sbjct 994 ILQQGWFSDSVLRPSLDTIIKEL 1016
Score = 70.5 bits (171), Expect = 9e-11, Method: Composition-based stats.
Identities = 21/138 (15%), Positives = 58/138 (42%), Gaps = 9/138 (7%)
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667
++ + + + D ++ G+ +G+ V +K ++ S +D + +++ +
Sbjct 687 IQPNEITNIKTIIVKDSYSILEGQYKGK--LVSIKQINGSINDFEMKQLG---VLASIKS 741
Query 668 THLAFVHGVCVRGPENIMVTEYV-EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726
GV E +++E+V +G L ++ + + + +A Q+ ++ YL
Sbjct 742 PLAVRFIGVVFNTDEYAIISEHVGNNGSLLTLMQNHSNQLNWSNTIDLAIQITQSIQYLH 801
Query 727 NK--NLVHGNVCGRNILL 742
++H N+ + L
Sbjct 802 KHQPPILHRNI-TSDCFL 818
Score = 65.5 bits (158), Expect = 2e-09, Method: Composition-based stats.
Identities = 23/115 (20%), Positives = 49/115 (43%), Gaps = 11/115 (10%)
Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV-P 982
G++V++K + +L ++ +++ G + E ++ E+V
Sbjct 713 GKLVSIKQINGSINDFEMKQL----GVLASIKSPLAVRFIGVVFNTDE--YAIISEHVGN 766
Query 983 LGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDN 1033
GSL + HS + + + A QI + + YLH +HR++ + LL +
Sbjct 767 NGSLLTLMQNHSNQLNWSNTIDLAIQITQSIQYLHKHQPPILHRNITSDCFLLSS 821
Score = 53.5 bits (127), Expect = 1e-05, Method: Composition-based stats.
Identities = 22/136 (16%), Positives = 44/136 (32%), Gaps = 18/136 (13%)
Query 755 IKLSDPGVGLGAL-----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
IK+ D G+ S +E + PE L N+ S D + L E+
Sbjct 891 IKVHDFGLSRFNTQENEESLKEIKGNFLYSPPELLS--LNTYSNKSDIYSLSIVLYELFE 948
Query 810 DG-----EAPLQSRSPSEKEHFYQR------QHRLPEPSCPQLATLTSQCLTYEPTQRPS 858
+ P + + + + +++ + Q + RPS
Sbjct 949 TCLTKTYKKPYHEVTLDFDFQIIHKTSKLNLRPTISNNMPNEISKILQQGWFSDSVLRPS 1008
Query 859 FRTILRDLTRLQPHNL 874
TI+++L + +
Sbjct 1009 LDTIIKELLICKKNLC 1024
>sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens OX=9606
GN=LIMK1 PE=1 SV=3
Length=647
Score = 238 bits (607), Expect = 1e-65, Method: Composition-based stats.
Identities = 74/309 (24%), Positives = 132/309 (43%), Gaps = 33/309 (11%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
+F L LG+G FG+ T+ TGE++ +K L + + +
Sbjct 328 CRPHRIFRPSDLIHGEVLGKGCFGQ----AIKVTHRETGEVMVMKEL-IRFDEETQRTFL 382
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLF 1003
+E+ ++R L H +++K+ G +K L + EY+ G+LR + +Q + F
Sbjct 383 KEVKVMRCLEHPNVLKFIGVLYK--DKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSF 440
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY--------- 1054
A+ I GMAYLH+ + IHRDL + N L+ ++ V + DFGLA+ + +
Sbjct 441 AKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKK 500
Query 1055 --YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
+ R +W APE + + DV+SFG+ L E++ ++ + ++
Sbjct 501 PDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFG 560
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+G + P CP + + C + + RP+F L L+T+
Sbjct 561 LNVRGFLDRY-------------CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETL 607
Query 1173 HEKYQGQAP 1181
G P
Sbjct 608 RMHLAGHLP 616
Score = 210 bits (534), Expect = 4e-56, Method: Composition-based stats.
Identities = 70/396 (18%), Positives = 134/396 (34%), Gaps = 57/396 (14%)
Query 501 RLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSN 560
RL + +E + G G + G + LR C + + +
Sbjct 248 RLLQLTLEHDPHDTLGHGLGPETSPLSSPAYTPSGEAGSSARQKPVLRSCSIDRSPGAGS 307
Query 561 L---IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
L R +L + ++ LG+G + R G
Sbjct 308 LGSPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGE---- 363
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
+V+K L + F + +M + H ++ GV
Sbjct 364 --------------------VMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVL 403
Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737
+ +TEY++ G L ++ P + ++ A+ +AS ++YL + N++H ++
Sbjct 404 YKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNS 463
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------------------VERIPWL 779
N L+ + + ++D G+ + + + V W+
Sbjct 464 HNCLVRE-------NKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWM 516
Query 780 APECLPGGANSLSTAMDKWGFGATLLEIC--FDGEAPLQSRSPSEKEHFYQRQHRLPEPS 837
APE + G S +D + FG L EI + + R+ + R P+
Sbjct 517 APEMING--RSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPN 574
Query 838 CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
CP +T +C +P +RPSF + L L+ H
Sbjct 575 CPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMH 610
>sp|P04626|ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2
OS=Homo sapiens OX=9606 GN=ERBB2 PE=1 SV=1
Length=1255
Score = 247 bits (630), Expect = 1e-65, Method: Composition-based stats.
Identities = 87/272 (32%), Positives = 133/272 (49%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + VA+K L+ + P+ E ++ + ++ +
Sbjct 726 LGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRL 785
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C +QLV + +P G L D++ R +G LL + QI +GM+YL +
Sbjct 786 LGICLTST---VQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLV 842
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W A E + +F +
Sbjct 843 HRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWMALESILRRRFTH 901
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + + +LLE+GERLP+P C
Sbjct 902 QSDVWSYGVTVWELMTFG--------------AKPYDGIPAREIPDLLEKGERLPQPPIC 947
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW ++ RP F L+ +
Sbjct 948 TIDVYMIMVKCWMIDSECRPRFRELVSEFSRM 979
Score = 224 bits (570), Expect = 2e-58, Method: Composition-based stats.
Identities = 82/474 (17%), Positives = 163/474 (34%), Gaps = 49/474 (10%)
Query 419 LVDGYFRLTADSSHYL-CHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHW-S 476
++ G R ++ H L CH P + GP + V + + S
Sbjct 546 VLQGLPREYVNARHCLPCHPECQP---QNGSVTCFGPEADQCVACAHYKDPPFCVARCPS 602
Query 477 TSHPYRLILTVAQRSQAPDGMQSLRL--RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQ 534
P + + + Q + ++ D E S+ +
Sbjct 603 GVKPDLSYMPIWKFPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVGIL 662
Query 535 GCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL---SQLSFHRVDQKEITQ 591
++ ++R T ++ P T + +Q + + E+ +
Sbjct 663 LVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRK 722
Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHD 650
+ LG G VY+G +G ++ V +KVL +
Sbjct 723 VKVLGSGAFGTVYKGIWIPDGENV--------------------KIPVAIKVLRENTSPK 762
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
+ A +M+ V +++ + G+C+ +VT+ + +G L +R RG +
Sbjct 763 ANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQLMPYGCLLDHVRENRGRLGSQD 821
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------ 764
+ Q+A +SYLE+ LVH ++ RN+L+ +K++D G+
Sbjct 822 LLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPN-------HVKITDFGLARLLDIDE 874
Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ I W+A E + + D W +G T+ E+ G P E
Sbjct 875 TEYHADGGKVPIKWMALESIL--RRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIP 932
Query 825 HFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
++ RLP+P + + +C + RP FR ++ + +R+
Sbjct 933 DLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRF 986
>sp|Q9ZVR7|PSKR1_ARATH Phytosulfokine receptor 1 OS=Arabidopsis
thaliana OX=3702 GN=PSKR1 PE=1 SV=4
Length=1008
Score = 244 bits (624), Expect = 1e-65, Method: Composition-based stats.
Identities = 78/279 (28%), Positives = 119/279 (43%), Gaps = 19/279 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V Y T G+ VA+K L DCG R ++ E++ L H +++
Sbjct 740 IGCGGFGMV----YKATLPD-GKKVAIKKLSGDCGQIERE-FEAEVETLSRAQHPNLVLL 793
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHA- 1016
+G C + ++ L+ Y+ GSL +L + + L AQ +G+ YLH
Sbjct 794 RGFCFYKNDR--LLIYSYMENGSLDYWLHERNDGPALLKWKTRLRIAQGAAKGLLYLHEG 851
Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H +HRD+ + N+LLD + + DFGLA+ + + V D + + PE +
Sbjct 852 CDPHILHRDIKSSNILLDENFNSHLADFGLARLMSPYETH--VSTDLVGTLGYIPPEYGQ 909
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQMTVLRLTELLERGER 1133
Y DV+SFGV L ELLT P +LI R +E+ +
Sbjct 910 ASVATYKGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHESRASEVFDPLIY 969
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
DK V + C RPT + L+ L V
Sbjct 970 SKENDKEMFRVLEIACLCLSENPKQRPTTQQLVSWLDDV 1008
Score = 217 bits (553), Expect = 1e-56, Method: Composition-based stats.
Identities = 65/321 (20%), Positives = 110/321 (34%), Gaps = 64/321 (20%)
Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
N +LS+ + Q + +G G VY+ L
Sbjct 718 NDKELSYDDLLDSTNSFDQANIIGCGGFGMVYKATLPDGK-------------------- 757
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
+V +K L I F +S+ H +L + G C + +++ Y+E+
Sbjct 758 -----KVAIKKLSGDCGQIEREFEAEVETLSRAQHPNLVLLRGFCFYKNDRLLIYSYMEN 812
Query 693 GPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLG 746
G LD WL R G + W ++ +AQ A L YL +++H ++ NILL
Sbjct 813 GSLDYWLHERNDGPALLKWKTRLRIAQGAAKGLLYLHEGCDPHILHRDIKSSNILLDE-- 870
Query 747 LAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFG 801
+ L+D G+ E V + ++ PE + D + FG
Sbjct 871 -----NFNSHLADFGLARLMSPYETHVSTDLVGTLGYIPPEYGQASVATY--KGDVYSFG 923
Query 802 ATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLA------------TL 844
LLE+ D P R + + R E P + +
Sbjct 924 VVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHESRASEVFDPLIYSKENDKEMFRVLEI 983
Query 845 TSQCLTYEPTQRPSFRTILRD 865
CL+ P QRP+ + ++
Sbjct 984 ACLCLSENPKQRPTTQQLVSW 1004
>sp|P0CD62|LIMKB_DICDI Probable LIM domain-containing serine/threonine-protein
kinase DDB_G0286997 OS=Dictyostelium discoideum
OX=44689 GN=DDB_G0286997 PE=3 SV=1
Length=966
Score = 244 bits (623), Expect = 1e-65, Method: Composition-based stats.
Identities = 73/310 (24%), Positives = 125/310 (40%), Gaps = 30/310 (10%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
L+ D++ + S K + + G GKV Y + VA
Sbjct 674 LKHQTFDDIVGEVLNKRISIYKQLVKDDVIFGDVIAAGASGKVYKGIYKGRD------VA 727
Query 929 VKALKADCGPQHRSGWKQEIDILRTLY--HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
+K ++ + + +E+ I+ + H + ++ G Q +K L V E V GSL
Sbjct 728 IKVYSSENFCFNIDEFDREVTIMSLIDSDHPNFTRFYGA-NKQNKKYLFHVSELVKSGSL 786
Query 987 RDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
RD L + L A I M +LH+ IHRDL + NVL+ D K+ DFG
Sbjct 787 RDLLLDKEKPLLYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGT 846
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
++ V + + + +PE K + DV++FG+ L+E++ +
Sbjct 847 SRNV----DLAKHMTMNLGTSCYMSPELFKGNGYDETCDVYAFGIVLWEIIARKEP---- 898
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ + ++ +G+R P CP E L+K CW + RP+F+
Sbjct 899 -----------YENINSWSIPVMVAKGDRPTIPADCPSEYSKLIKACWTDKPKKRPSFKE 947
Query 1165 LIPILKTVHE 1174
+ LK + E
Sbjct 948 ICDTLKKISE 957
Score = 178 bits (451), Expect = 3e-44, Method: Composition-based stats.
Identities = 57/305 (19%), Positives = 112/305 (37%), Gaps = 45/305 (15%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
LN + ++ + ++ + G VY+G + GRD
Sbjct 687 LNKRISIYKQLVKDDVIFGDVIAAGASGKVYKG--------------------IYKGRD- 725
Query 634 GQELRVVLKVLDPSHHDI-ALAFYETASLMSQVS--HTHLAFVHGVCVRGPENIM-VTEY 689
V +KV + F ++MS + H + +G + + + V+E
Sbjct 726 -----VAIKVYSSENFCFNIDEFDREVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSEL 780
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
V+ G L L + + ++ +A +A+A+ +L + ++H ++ N+L+
Sbjct 781 VKSGSLRDLLLDKEKPLLYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITE----- 835
Query 750 GTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
K+ D G + +++PE G N D + FG L E
Sbjct 836 --DFTAKVIDFGTSRNVDLAKHMTMNLGTSCYMSPELFKG--NGYDETCDVYAFGIVLWE 891
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
I E P ++ + + R +P + + L C T +P +RPSF+ I
Sbjct 892 IIARKE-PYENINSWSIPVMVAKGDRPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICD 950
Query 865 DLTRL 869
L ++
Sbjct 951 TLKKI 955
>sp|Q8LPB4|PSKR1_DAUCA Phytosulfokine receptor 1 OS=Daucus carota
OX=4039 GN=PSKR PE=1 SV=1
Length=1021
Score = 244 bits (624), Expect = 1e-65, Method: Composition-based stats.
Identities = 77/279 (28%), Positives = 118/279 (42%), Gaps = 19/279 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V Y T G VA+K L D G R ++ E++ L H +++
Sbjct 749 IGCGGFGLV----YKATLPD-GTKVAIKRLSGDTGQMDRE-FQAEVETLSRAQHPNLVHL 802
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLH-- 1015
G C + +K L+ Y+ GSL +L S+ L A+ EG+AYLH
Sbjct 803 LGYCNYKNDK--LLIYSYMDNGSLDYWLHEKVDGPPSLDWKTRLRIARGAAEGLAYLHQS 860
Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H +HRD+ + N+LL + + + DFGLA+ + + V D + + PE +
Sbjct 861 CEPHILHRDIKSSNILLSDTFVAHLADFGLARLILPYDTH--VTTDLVGTLGYIPPEYGQ 918
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQMTVLRLTELLERGER 1133
Y DV+SFGV L ELLT P +LI T R +E+ +
Sbjct 919 ASVATYKGDVYSFGVVLLELLTGRRPMDVCKPRGSRDLISWVLQMKTEKRESEIFDPFIY 978
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ V + C RPT + L+ L+ +
Sbjct 979 DKDHAEEMLLVLEIACRCLGENPKTRPTTQQLVSWLENI 1017
Score = 219 bits (557), Expect = 5e-57, Method: Composition-based stats.
Identities = 61/325 (19%), Positives = 114/325 (35%), Gaps = 66/325 (20%)
Query 577 SQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
++LS + Q + +G G VY+ L
Sbjct 729 NELSLDDILKSTSSFNQANIIGCGGFGLVYKATLPDG----------------------- 765
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+V +K L + F +S+ H +L + G C + +++ Y+++G
Sbjct 766 --TKVAIKRLSGDTGQMDREFQAEVETLSRAQHPNLVHLLGYCNYKNDKLLIYSYMDNGS 823
Query 695 LDVWLRRE-RGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLA 748
LD WL + G + W ++ +A+ A L+YL +++H ++ NILL+ +A
Sbjct 824 LDYWLHEKVDGPPSLDWKTRLRIARGAAEGLAYLHQSCEPHILHRDIKSSNILLSDTFVA 883
Query 749 EGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
L+D G+ L + V + ++ PE + D + FG
Sbjct 884 H-------LADFGLARLILPYDTHVTTDLVGTLGYIPPEYGQASVATY--KGDVYSFGVV 934
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQR------QHRLPEPSCPQLAT------------LT 845
LLE+ G P+ P + R E P + +
Sbjct 935 LLELL-TGRRPMDVCKPRGSRDLISWVLQMKTEKRESEIFDPFIYDKDHAEEMLLVLEIA 993
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQ 870
+CL P RP+ + ++ L +
Sbjct 994 CRCLGENPKTRPTTQQLVSWLENID 1018
>sp|Q8BYG9|EPHAA_MOUSE Ephrin type-A receptor 10 OS=Mus musculus
OX=10090 GN=Epha10 PE=2 SV=2
Length=1007
Score = 244 bits (624), Expect = 1e-65, Method: Composition-based stats.
Identities = 89/277 (32%), Positives = 127/277 (46%), Gaps = 23/277 (8%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG G FG + C G E+ VAV L+ C R + E L H HI+
Sbjct 649 SLGAGRFGTLCCGCLQ--LPGRQELPVAVHTLRDGCSDSQRLSFLAEALTLGQFDHSHIV 706
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQH 1018
+ +G L +V EY+ LG+L D+L H L AQL+ + M YL
Sbjct 707 RLEGVVTRGN--PLMIVTEYMNLGALDDFLRHHEGELVAAQLMGLLPGLASAMKYLSEMG 764
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
Y+HR LAAR VL+ + L KI FG + + E G SP W APE L+ F
Sbjct 765 YVHRGLAARRVLVSSGLLCKISGFG--RGPRDRAEAVYTTMSGRSPALWAAPETLQFGHF 822
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
ASDVWSFG+ ++E++ + M+ + + +E G RLP P
Sbjct 823 SSASDVWSFGIVMWEVMAFGER--------------PYWDMSGQDVIKAVEDGFRLPPPR 868
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
CP +++ LM CW+ + S RP F + IL + ++
Sbjct 869 NCPSQLHRLMLECWQKDPSERPRFSQIHSILSKMGQE 905
Score = 234 bits (596), Expect = 5e-62, Method: Composition-based stats.
Identities = 99/391 (25%), Positives = 143/391 (37%), Gaps = 62/391 (16%)
Query 547 LRRCCLPQPGETSN---------LIIMRGARASPRTLNLSQLSFH----RVDQKEITQLS 593
RR C + ++ + R P++ + H +D K +T
Sbjct 589 WRRPCDGKGSGNAHDEEELYFHFKVPTRRTFLDPQSCGDPLQAVHLFAKELDAKSVTLEK 648
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIA 652
LG G + G L++ G QEL V + L D
Sbjct 649 SLGAGRFGTLCCGCLQLPGR---------------------QELPVAVHTLRDGCSDSQR 687
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
L+F A + Q H+H+ + GV RG ++VTEY+ G LD +LR G + A M
Sbjct 688 LSFLAEALTLGQFDHSHIVRLEGVVTRGNPLMIVTEYMNLGALDDFLRHHEGELVAAQLM 747
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
+ LASA+ YL VH + R +L++ L K+S G G G R E
Sbjct 748 GLLPGLASAMKYLSEMGYVHRGLAARRVLVSSGLL-------CKIS--GFGRGPRDRAEA 798
Query 773 VERIP-------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
V W APE L G S+A D W FG + E+ GE P S +
Sbjct 799 VYTTMSGRSPALWAAPETLQFG--HFSSASDVWSFGIVMWEVMAFGERPYWDMSGQDVIK 856
Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
+ RLP P +CP QL L +C +P++RP F I L+++
Sbjct 857 AVEDGFRLPPPRNCPSQLHRLMLECWQKDPSERPRFSQIHSILSKMGQEPEPSKCASTTC 916
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
P FG V +
Sbjct 917 LRPPTPLADRAFSTFP-------SFGSVGAW 940
>sp|Q96285|LRK55_ARATH L-type lectin-domain containing receptor
kinase V.5 OS=Arabidopsis thaliana OX=3702 GN=LECRK55 PE=1
SV=1
Length=661
Score = 238 bits (608), Expect = 1e-65, Method: Composition-based stats.
Identities = 79/304 (26%), Positives = 132/304 (43%), Gaps = 17/304 (6%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
P A + K+ + LG+G FG+V Y T G+ +AVK D
Sbjct 320 QYGPHRFAYKELFNATKGFKEKQLLGKGGFGQV----YKGTLPGSDAEIAVKRTSHD-SR 374
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HS 994
Q S + EI + L H ++++ G C + ++L LV +Y+P GSL YL R
Sbjct 375 QGMSEFLAEISTIGRLRHPNLVRLLGYCRHK--ENLYLVYDYMPNGSLDKYLNRSENQER 432
Query 995 IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
+ Q + + + +LH + IHRD+ NVL+DN+ ++GDFGLAK +G
Sbjct 433 LTWEQRFRIIKDVATALLHLHQEWVQVIIHRDIKPANVLIDNEMNARLGDFGLAKLYDQG 492
Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE- 1110
+ + G + APE L+ + ++DV++FG+ + E++ + + E
Sbjct 493 FDPETSKVAG--TFGYIAPEFLRTGRATTSTDVYAFGLVMLEVVCGRRIIERRAAENEEY 550
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
L+ ++ + E R + V L C AS RP ++ IL
Sbjct 551 LVDWILELWENGKIFDAAEESIRQEQNRGQVELVLKLGVLCSHQAASIRPAMSVVMRILN 610
Query 1171 TVHE 1174
V +
Sbjct 611 GVSQ 614
Score = 214 bits (546), Expect = 2e-57, Method: Composition-based stats.
Identities = 52/258 (20%), Positives = 96/258 (37%), Gaps = 36/258 (14%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
K + LG+G VY+G L G + + +K
Sbjct 334 ATKGFKEKQLLGKGGFGQVYKGTL------------------------PGSDAEIAVKRT 369
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
F S + ++ H +L + G C +V +Y+ +G LD +L R
Sbjct 370 SHDSRQGMSEFLAEISTIGRLRHPNLVRLLGYCRHKENLYLVYDYMPNGSLDKYLNRSEN 429
Query 705 HVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLA-RLGLAEGTSPFIKLS 758
+ W + + + +A+AL +L + ++H ++ N+L+ + G KL
Sbjct 430 QERLTWEQRFRIIKDVATALLHLHQEWVQVIIHRDIKPANVLIDNEMNARLGDFGLAKLY 489
Query 759 DPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
D G + ++APE L G +T+ D + FG +LE+ G ++ R
Sbjct 490 DQGF---DPETSKVAGTFGYIAPEFLRTGRA--TTSTDVYAFGLVMLEVVC-GRRIIERR 543
Query 819 SPSEKEHFYQRQHRLPEP 836
+ +E+ L E
Sbjct 544 AAENEEYLVDWILELWEN 561
>sp|Q7X996|CIPK2_ORYSJ CBL-interacting protein kinase 2 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK2 PE=2 SV=1
Length=443
Score = 232 bits (592), Expect = 1e-65, Method: Composition-based stats.
Identities = 58/280 (21%), Positives = 115/280 (41%), Gaps = 26/280 (9%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEI 948
+ + + LG+G F KV Y N T E VA+K + + + K+EI
Sbjct 7 NMLMKKYEMGKLLGQGTFAKV----YHARNTETSESVAIKMIDKEKVLKGGLMDQIKREI 62
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008
+++ + H +I++ + + + V+E+V G L + + R + + QQ+
Sbjct 63 SVMKLVRHPNIVQLYEVMATKTK--IYFVLEHVKGGELFNKVQRGRLKEDAARKYFQQLI 120
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+ + H++ HRDL N+LLD + +K+ DFGL+ + + +P +
Sbjct 121 CAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSALADCKRQDGLLHTTCGTPA-YV 179
Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + + +D+WS GV L+ LL ++ + +
Sbjct 180 APEVINRRGYDGAKADIWSCGVILFVLLAGYLPFHD---------------KNLMDMYKK 224
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + E P +V L+ + S R + + ++
Sbjct 225 IGKAE-FKCPSWFNTDVRRLLLRILDPNPSTRISMDKIME 263
Score = 182 bits (462), Expect = 3e-48, Method: Composition-based stats.
Identities = 53/293 (18%), Positives = 98/293 (33%), Gaps = 45/293 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
K+ LGQGT VY R+ V +K++D
Sbjct 10 MKKYEMGKLLGQGTFAKVYHA------------------------RNTETSESVAIKMID 45
Query 646 PSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+ S+M V H ++ ++ V + V E+V+ G L + +
Sbjct 46 KEKVLKGGLMDQIKREISVMKLVRHPNIVQLYEVMATKTKIYFVLEHVKGGELFN--KVQ 103
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
RG + QQL A+ + ++ + H ++ N+LL + +K+SD G+
Sbjct 104 RGRLKEDAARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDE-------NSNLKVSDFGL 156
Query 763 GLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
A + ++APE + D W G L + G P
Sbjct 157 SALADCKRQDGLLHTTCGTPAYVAPEVINRRGYD-GAKADIWSCGVIL-FVLLAGYLPFH 214
Query 817 SRSPSEKE-HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
++ + + + + P + L + L P+ R S I+ +
Sbjct 215 DKNLMDMYKKIGKAEFKCPSWFNTDVRRLLLRILDPNPSTRISMDKIMENPWF 267
>sp|Q0WVM4|Y2239_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At2g23950 OS=Arabidopsis thaliana OX=3702
GN=At2g23950 PE=1 SV=1
Length=634
Score = 238 bits (606), Expect = 1e-65, Method: Composition-based stats.
Identities = 73/274 (27%), Positives = 120/274 (44%), Gaps = 15/274 (5%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + G G +VAVK LK G S ++ E++++ H ++++
Sbjct 305 LGAGGFGNVYRGKF-----GDGTVVAVKRLKDVNGTSGNSQFRTELEMISLAVHRNLLRL 359
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ---H 1018
G C E+ LV Y+ GS+ L + ++ A G+ YLH Q
Sbjct 360 IGYCASSSER--LLVYPYMSNGSVASRLKAKPALDWNTRKKIAIGAARGLFYLHEQCDPK 417
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ A N+LLD +GDFGLAK + HE V V APE L +
Sbjct 418 IIHRDVKAANILLDEYFEAVVGDFGLAKLL--NHEDSHVTTAVRGTVGHIAPEYLSTGQS 475
Query 1079 YYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+DV+ FG+ L EL+T + ++ ++ + +++ EL++R
Sbjct 476 SEKTDVFGFGILLLELITGMRALEFGKSVSQKGAMLEWVRKLHKEMKVEELVDRELGTTY 535
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
E+ + C + + RP ++ +L+
Sbjct 536 DRIEVGEMLQVALLCTQFLPAHRPKMSEVVQMLE 569
Score = 190 bits (483), Expect = 1e-49, Method: Composition-based stats.
Identities = 69/366 (19%), Positives = 113/366 (31%), Gaps = 66/366 (18%)
Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
NL +F V + S LG G NVY G+
Sbjct 283 NLRSFTFRELHVATDGFSSKSILGAGGFGNVYRGK------------------------- 317
Query 633 RGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
G V +K L + F ++S H +L + G C E ++V Y+
Sbjct 318 FGDGTVVAVKRLKDVNGTSGNSQFRTELEMISLAVHRNLLRLIGYCASSSERLLVYPYMS 377
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748
+G + L+ + + + +A A L YL + ++H +V NILL A
Sbjct 378 NGSVASRLKA-KPALDWNTRKKIAIGAARGLFYLHEQCDPKIIHRDVKAANILLDEYFEA 436
Query 749 EGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+ D G+ + V + +APE L G + S D +GFG
Sbjct 437 V-------VGDFGLAKLLNHEDSHVTTAVRGTVGHIAPEYLSTGQS--SEKTDVFGFGIL 487
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS------------------CPQLATLT 845
LLE+ A +S S+K + +L + ++ +
Sbjct 488 LLELITGMRALEFGKSVSQKGAMLEWVRKLHKEMKVEELVDRELGTTYDRIEVGEMLQVA 547
Query 846 SQCLTYEPTQRPSFRTILRDL--TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
C + P RP +++ L L A +
Sbjct 548 LLCTQFLPAHRPKMSEVVQMLEGDGLAERWAASHDHSHFYHANMSYRTITSTDGNNQTKH 607
Query 904 GEGHFG 909
G G
Sbjct 608 LFGSSG 613
>sp|Q9ZRF9|RPK1_ARATH Probable LRR receptor-like serine/threonine-protein
kinase RPK1 OS=Arabidopsis thaliana OX=3702 GN=RPK1
PE=1 SV=1
Length=540
Score = 235 bits (599), Expect = 2e-65, Method: Composition-based stats.
Identities = 75/287 (26%), Positives = 117/287 (41%), Gaps = 19/287 (7%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
Y +G G FG PTN + AVK L Q + EI L +
Sbjct 260 YFSNSNCIGHGGFGSTYKAEVSPTN-----VFAVKRLSVG-RFQGDQQFHAEISALEMVR 313
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMA 1012
H +++ G E + L+ Y+ G+L+D++ S I L A + ++
Sbjct 314 HPNLVMLIGY--HASETEMFLIYNYLSGGNLQDFIKERSKAAIEWKVLHKIALDVARALS 371
Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH Q +HRD+ N+LLDN+ + DFGL+K + G V + A
Sbjct 372 YLHEQCSPKVLHRDIKPSNILLDNNYNAYLSDFGLSKLL--GTSQSHVTTGVAGTFGYVA 429
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHC---DSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
PE + +DV+S+G+ L EL++ D S S ++ A ++ + E
Sbjct 430 PEYAMTCRVSEKADVYSYGIVLLELISDKRALDPSFSSHENGFNIVSWAHMMLSQGKAKE 489
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ G P EV HL C S RPT + + +LK +
Sbjct 490 VFTTGLWETGPPDDLVEVLHLALKCTVDSLSIRPTMKQAVRLLKRIQ 536
Score = 181 bits (459), Expect = 4e-47, Method: Composition-based stats.
Identities = 48/243 (20%), Positives = 83/243 (34%), Gaps = 43/243 (18%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+ + +G G + Y+ + +K L
Sbjct 261 FSNSNCIGHGGFGSTYKAEVSPTNVF-------------------------AVKRLSVGR 295
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVP 707
F+ S + V H +L + G E ++ Y+ G L +++ R + +
Sbjct 296 FQGDQQFHAEISALEMVRHPNLVMLIGYHASETEMFLIYNYLSGGNLQDFIKERSKAAIE 355
Query 708 MAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+A +A ALSYL + ++H ++ NILL A LSD G+
Sbjct 356 WKVLHKIALDVARALSYLHEQCSPKVLHRDIKPSNILLDNNYNAY-------LSDFGLSK 408
Query 765 GALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ + V ++APE +S D + +G LLE+ D A S S
Sbjct 409 LLGTSQSHVTTGVAGTFGYVAPEYAMTC--RVSEKADVYSYGIVLLELISDKRALDPSFS 466
Query 820 PSE 822
E
Sbjct 467 SHE 469
>sp|A0A2R6XIK6|PRAF_MARPO RAF-like serine/threonine-protein kinase
PRAF OS=Marchantia polymorpha OX=3197 GN=PRAF PE=1 SV=1
Length=1680
Score = 247 bits (631), Expect = 2e-65, Method: Composition-based stats.
Identities = 78/294 (27%), Positives = 124/294 (42%), Gaps = 39/294 (13%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-----GPQHR--SGWKQEIDILRTL 954
+LG G FG V + T+ VA+K +KA C Q R + +E L L
Sbjct 1394 ELGSGTFGTVYHGKWRGTD------VAIKRIKASCFAGRPSEQERLIEDFWREACNLGHL 1447
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMA 1012
+H +++ + G D +L V EY+ GSL+ L + +I + LL A GM
Sbjct 1448 HHPNVVAFYGVVADGPGGTLATVTEYMVNGSLKQVLQKKDRTIDRRKRLLIAMDAAFGME 1507
Query 1013 YLHAQHYIHRDLAARNVLLD----NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
YLH ++ +H DL N+L++ + + K+GD GL+K V + W
Sbjct 1508 YLHGKNIVHFDLKCENLLVNMRDPHRPICKVGDLGLSKV----KHQTMVSGGVRGTLPWM 1563
Query 1069 APECLKEYK--FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
APE L DV+SFG+ ++ELLT + + +
Sbjct 1564 APELLNGNSSLVTEKVDVFSFGIVMWELLTGEEPYDKMHYGAI--------------IGG 1609
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180
++ R P C LM+ CW E + RP+F ++ L+T+ Q +
Sbjct 1610 IVNNTLRPLIPSWCDPAWRSLMERCWANEPAVRPSFSDIAKELRTMAAALQPKT 1663
Score = 230 bits (586), Expect = 5e-60, Method: Composition-based stats.
Identities = 67/328 (20%), Positives = 121/328 (37%), Gaps = 46/328 (14%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
+ ++ +L LG GT VY G+ R V
Sbjct 1381 LQTIKNADLEELRELGSGTFGTVYHGKWRGTD--------------------------VA 1414
Query 641 LKVLDPS--------HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEYV 690
+K + S + F+ A + + H ++ +GV GP + VTEY+
Sbjct 1415 IKRIKASCFAGRPSEQERLIEDFWREACNLGHLHHPNVVAFYGVVADGPGGTLATVTEYM 1474
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
+G L L+++ + ++++A A + YL KN+VH ++ N+L+ + +
Sbjct 1475 VNGSLKQVLQKKDRTIDRRKRLLIAMDAAFGMEYLHGKNIVHFDLKCENLLV---NMRDP 1531
Query 751 TSPFIKLSDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
P K+ D G+ + +PW+APE L G ++ ++ +D + FG + E+
Sbjct 1532 HRPICKVGDLGLSKVKHQTMVSGGVRGTLPWMAPELLNGNSSLVTEKVDVFSFGIVMWEL 1591
Query 808 CFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
GE P + +P P +L +C EP RPSF I +
Sbjct 1592 L-TGEEPYDKMHYGAIIGGIVNNTLRPLIPSWCDPAWRSLMERCWANEPAVRPSFSDIAK 1650
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVF 892
+L + P +
Sbjct 1651 ELRTMAAALQPKTQAQTQGQSHPHPQMQ 1678
>sp|Q8H1G6|PTI11_ARATH PTI1-like tyrosine-protein kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=PTI11 PE=1 SV=1
Length=361
Score = 229 bits (584), Expect = 2e-65, Method: Composition-based stats.
Identities = 71/286 (25%), Positives = 121/286 (42%), Gaps = 22/286 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG +G+V G VA+K L + + + ++ ++ L HE++I+
Sbjct 74 IGEGSYGRVYYATL-----NDGVAVALKKLDVAPEAETDTEFLSQVSMVSRLKHENLIQL 128
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------IGLAQLLLFAQQICEGMA 1012
G C D + L E+ +GSL D L + + A + G+
Sbjct 129 LGFCVDGNLR--VLAYEFATMGSLHDILHGRKGVQGAQPGPTLDWITRVKIAVEAARGLE 186
Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH + IHRD+ + NVLL D KI DF L+ P+ ++A
Sbjct 187 YLHEKSQPPVIHRDIRSSNVLLFEDYKAKIADFNLSNQAPDNAARLH-STRVLGTFGYHA 245
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE + SDV+SFGV L ELLT + P L+ A +++ ++ + +
Sbjct 246 PEYAMTGQLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRLSEDKVKQCI 305
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ + P K ++ + C + EA FRP ++ L+ + +
Sbjct 306 DPKLKADYPPKAVAKLAAVAALCVQYEAEFRPNMSIVVKALQPLLK 351
Score = 195 bits (496), Expect = 1e-53, Method: Composition-based stats.
Identities = 54/283 (19%), Positives = 97/283 (34%), Gaps = 54/283 (19%)
Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
+ + LS V + + +G+G+ VY L
Sbjct 50 PIEVPPLSLDEVKEKTENFGSKALIGEGSYGRVYYATLNDG------------------- 90
Query 631 RDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
+ V LK LD + + F S++S++ H +L + G CV G ++ E+
Sbjct 91 ------VAVALKKLDVAPEAETDTEFLSQVSMVSRLKHENLIQLLGFCVDGNLRVLAYEF 144
Query 690 VEHGPLDVWLRRERG--------HVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGR 738
G L L +G + ++ +A + A L YL K+ ++H ++
Sbjct 145 ATMGSLHDILHGRKGVQGAQPGPTLDWITRVKIAVEAARGLEYLHEKSQPPVIHRDIRSS 204
Query 739 NILLARLGLAEGTSPFIKLSDPGVG------LGALSREERVERIPWLAPECLPGGANSLS 792
N+LL K++D + L + + APE G L+
Sbjct 205 NVLLFE-------DYKAKIADFNLSNQAPDNAARLHSTRVLGTFGYHAPEYAMTG--QLT 255
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
D + FG LLE+ + + ++ RL E
Sbjct 256 QKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRLSE 298
>sp|Q9FJ54|CIPKK_ARATH CBL-interacting serine/threonine-protein
kinase 20 OS=Arabidopsis thaliana OX=3702 GN=CIPK20 PE=1 SV=1
Length=439
Score = 232 bits (591), Expect = 2e-65, Method: Composition-based stats.
Identities = 68/268 (25%), Positives = 113/268 (42%), Gaps = 26/268 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960
LG+G F KV Y N TGE VA+K + + K+EI ++R + H H++
Sbjct 18 LGQGTFAKV----YHARNIKTGESVAIKVIDKQKVAKVGLIDQIKREISVMRLVRHPHVV 73
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ + + MEYV G L D + + + + QQ+ + Y H++
Sbjct 74 FLHEVMASKTK--IYFAMEYVKGGELFDKVSKGKLKENIARKYFQQLIGAIDYCHSRGVY 131
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
HRDL N+LLD + +KI DFGL+ + + +P + APE + + +
Sbjct 132 HRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPA-YVAPEVIGKKGYDG 190
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+DVWS GV LY LL + ++ + + +GE P+
Sbjct 191 AKADVWSCGVVLYVLLAGFLPFH---------------EQNLVEMYRKITKGE-FKCPNW 234
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
P EV L+ + + R E ++
Sbjct 235 FPPEVKKLLSRILDPNPNSRIKIEKIME 262
Score = 187 bits (475), Expect = 4e-50, Method: Composition-based stats.
Identities = 61/312 (20%), Positives = 102/312 (33%), Gaps = 45/312 (14%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V ++ LGQGT VY R G V +KV
Sbjct 7 VLMRKYELGRLLGQGTFAKVYHARNIKTGES------------------------VAIKV 42
Query 644 LDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
+D + + S+M V H H+ F+H V + EYV+ G L +
Sbjct 43 IDKQKVAKVGLIDQIKREISVMRLVRHPHVVFLHEVMASKTKIYFAMEYVKGGELFD--K 100
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+G + QQL A+ Y ++ + H ++ N+LL G +K+SD
Sbjct 101 VSKGKLKENIARKYFQQLIGAIDYCHSRGVYHRDLKPENLLLDENGD-------LKISDF 153
Query 761 GVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ S++ ++APE + D W G L + G P
Sbjct 154 GLSALRESKQQDGLLHTTCGTPAYVAPEVIGKKGYD-GAKADVWSCGVVLY-VLLAGFLP 211
Query 815 LQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
++ E + + P P++ L S+ L P R I+ + +
Sbjct 212 FHEQNLVEMYRKITKGEFKCPNWFPPEVKKLLSRILDPNPNSRIKIEKIMENSWFQKGFK 271
Query 874 LADVLTVNPDSP 885
+
Sbjct 272 KIETPKSPESHQ 283
>sp|Q9FN94|RLK0_ARATH Receptor-like protein kinase At5g59670 OS=Arabidopsis
thaliana OX=3702 GN=At5g59670 PE=1 SV=1
Length=868
Score = 242 bits (618), Expect = 2e-65, Method: Composition-based stats.
Identities = 80/320 (25%), Positives = 132/320 (41%), Gaps = 17/320 (5%)
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918
TI++ L ++ DV N S + + R LG+G FG V
Sbjct 526 MSTIVKGLRLPPRTSMVDVTFSNKKSKRFTYSEVVQVTKNFQRVLGKGGFGMVYHGTVKG 585
Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978
+ E VAVK L Q +K E+D+L ++H +++ G C + L LV
Sbjct 586 S-----EQVAVKVLSQSST-QGSKEFKAEVDLLLRVHHTNLVSLVGYCCEGD--YLALVY 637
Query 979 EYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLL 1031
E++P G L+ +L I + L A + G+ YLH +HRD+ N+LL
Sbjct 638 EFLPNGDLKQHLSGKGGNSIINWSIRLRIALEAALGLEYLHIGCTPPMVHRDVKTANILL 697
Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091
D + K+ DFGL+++ +G + + + PEC + SDV+SFG+ L
Sbjct 698 DENFKAKLADFGLSRSF-QGEGESQESTTIAGTLGYLDPECYHSGRLGEKSDVYSFGIVL 756
Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
E++T+ + + QM + E+++ R L +C
Sbjct 757 LEMITNQPVINQT-SGDSHITQWVGFQMNRGDILEIMDPNLRKDYNINSAWRALELAMSC 815
Query 1152 WETEASFRPTFENLIPILKT 1171
+S RP+ +I LK
Sbjct 816 AYPSSSKRPSMSQVIHELKE 835
Score = 218 bits (555), Expect = 2e-57, Method: Composition-based stats.
Identities = 76/345 (22%), Positives = 122/345 (35%), Gaps = 69/345 (20%)
Query 563 IMRGARASPRT----LNLSQLSFHRVDQKEITQL-----SHLGQGTRTNVYEGRLRVEGS 613
I++G R PRT + S R E+ Q+ LG+G VY G ++
Sbjct 529 IVKGLRLPPRTSMVDVTFSNKKSKRFTYSEVVQVTKNFQRVLGKGGFGMVYHGTVKGSE- 587
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
+V +KVL S + F L+ +V HT+L +
Sbjct 588 ------------------------QVAVKVLSQSSTQGSKEFKAEVDLLLRVHHTNLVSL 623
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NK 728
G C G +V E++ +G L L + G+ + W ++ +A + A L YL
Sbjct 624 VGYCCEGDYLALVYEFLPNGDLKQHLSGKGGNSIINWSIRLRIALEAALGLEYLHIGCTP 683
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPE 782
+VH +V NILL + KL+D G+ + + +L PE
Sbjct 684 PMVHRDVKTANILLDE-------NFKAKLADFGLSRSFQGEGESQESTTIAGTLGYLDPE 736
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ---SRSPSEKEHFYQRQHRLPEPSCP 839
C G L D + FG LLE+ + Q ++ F + + E P
Sbjct 737 CYHSG--RLGEKSDVYSFGIVLLEMITNQPVINQTSGDSHITQWVGFQMNRGDILEIMDP 794
Query 840 QLA------------TLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
L L C ++RPS ++ +L
Sbjct 795 NLRKDYNINSAWRALELAMSCAYPSSSKRPSMSQVIHELKECIAC 839
>sp|Q9SA72|Y1357_ARATH Probable receptor-like protein kinase At1g30570
OS=Arabidopsis thaliana OX=3702 GN=At1g30570 PE=3 SV=1
Length=849
Score = 242 bits (617), Expect = 2e-65, Method: Composition-based stats.
Identities = 72/283 (25%), Positives = 122/283 (43%), Gaps = 16/283 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FGKV + G ++A+K Q + ++ EI +L L H H++
Sbjct 526 IGVGGFGKVYRGELE-----DGTLIAIKR-ATPHSQQGLAEFETEIVMLSRLRHRHLVSL 579
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLH---A 1016
G C++ E + LV EY+ G+LR +L + Q L G+ YLH
Sbjct 580 IGFCDEHNE--MILVYEYMANGTLRSHLFGSNLPPLSWKQRLEACIGSARGLHYLHTGSE 637
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ IHRD+ N+LLD + + K+ DFGL+KA P ++ V + PE +
Sbjct 638 RGIIHRDVKTTNILLDENFVAKMSDFGLSKAGP-SMDHTHVSTAVKGSFGYLDPEYFRRQ 696
Query 1077 KFYYASDVWSFGVTLYE-LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ SDV+SFGV L+E + + + P + L A L +++ R
Sbjct 697 QLTEKSDVYSFGVVLFEAVCARAVINPTLPKDQINLAEWALSWQKQRNLESIIDSNLRGN 756
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
+ + + + C E RP ++ L+ V + ++
Sbjct 757 YSPESLEKYGEIAEKCLADEGKNRPMMGEVLWSLEYVLQIHEA 799
Score = 209 bits (531), Expect = 2e-54, Method: Composition-based stats.
Identities = 63/322 (20%), Positives = 98/322 (30%), Gaps = 61/322 (19%)
Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
L+ R K +G G VY G L
Sbjct 510 LAEIRAATKNFDDGLAIGVGGFGKVYRGELEDG-------------------------TL 544
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+ +K P F ++S++ H HL + G C E I+V EY+ +G L
Sbjct 545 IAIKRATPHSQQGLAEFETEIVMLSRLRHRHLVSLIGFCDEHNEMILVYEYMANGTLRSH 604
Query 699 LRRER-GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPF 754
L + ++ A L YL + ++H +V NILL +
Sbjct 605 LFGSNLPPLSWKQRLEACIGSARGLHYLHTGSERGIIHRDVKTTNILLDE-------NFV 657
Query 755 IKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
K+SD G+ S + +L PE L+ D + FG L E
Sbjct 658 AKMSDFGLSKAGPSMDHTHVSTAVKGSFGYLDPEYFR--RQQLTEKSDVYSFGVVLFEAV 715
Query 809 FDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLA------------TLTSQCLTY 851
P + +E +Q+Q L L + +CL
Sbjct 716 CARAVINPTLPKDQINLAEWALSWQKQRNLESIIDSNLRGNYSPESLEKYGEIAEKCLAD 775
Query 852 EPTQRPSFRTILRDLTRLQPHN 873
E RP +L L + +
Sbjct 776 EGKNRPMMGEVLWSLEYVLQIH 797
>sp|Q9P289|STK26_HUMAN Serine/threonine-protein kinase 26 OS=Homo
sapiens OX=9606 GN=STK26 PE=1 SV=2
Length=416
Score = 231 bits (589), Expect = 2e-65, Method: Composition-based stats.
Identities = 72/294 (24%), Positives = 123/294 (42%), Gaps = 24/294 (8%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933
+A + + K+ +G+G FG+V + ++ T ++VA+K +
Sbjct 1 MAHSPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEV----FKGIDNRTQQVVAIKIID 56
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993
+ +QEI +L ++ KY G + L ++MEY+ GS D L
Sbjct 57 LEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSK--LWIIMEYLGGGSALDLLRAG 114
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
Q+ ++I +G+ YLH++ IHRD+ A NVLL VK+ DFG+A + +
Sbjct 115 PFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD--- 171
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
R FW APE +++ + +D+WS G+T EL + PP
Sbjct 172 TQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIEL-----AKGEPP-------- 218
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
M +R+ L+ + + C + SFRPT + L+
Sbjct 219 --NSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLK 270
Score = 209 bits (532), Expect = 6e-58, Method: Composition-based stats.
Identities = 61/310 (20%), Positives = 119/310 (38%), Gaps = 44/310 (14%)
Query 570 SPRTLNLSQLSFHRVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
SP + + + + D +E T+L +G+G+ V++G
Sbjct 4 SPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGI--------------------- 42
Query 629 PGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
D + V +K++D D + +++SQ +++ +G ++G + ++
Sbjct 43 ---DNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIM 99
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
EY+ G LR G + +++ L YL ++ +H ++ N+LL+ G
Sbjct 100 EYLGGGSALDLLRA--GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGD 157
Query 748 AEGTSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+KL+D GV + R V W+APE + A + D W G T
Sbjct 158 -------VKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSA--YDSKADIWSLGIT 208
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861
+E+ GE P P + + L CL +P+ RP+ +
Sbjct 209 AIELA-KGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKE 267
Query 862 ILRDLTRLQP 871
+L+ ++
Sbjct 268 LLKHKFIVKN 277
>sp|F4IB81|LYK3_ARATH LysM domain receptor-like kinase 3 OS=Arabidopsis
thaliana OX=3702 GN=LYK3 PE=2 SV=1
Length=651
Score = 238 bits (606), Expect = 2e-65, Method: Composition-based stats.
Identities = 72/292 (25%), Positives = 122/292 (42%), Gaps = 34/292 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G++G V + VAVK + A + E+ +L ++H ++++
Sbjct 347 LGHGNYGSVYFGLLRE------QEVAVKRMTATKT----KEFAAEMKVLCKVHHSNLVEL 396
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP------RHSIGLAQLLLFAQQICEGMAYLHA 1016
G E L +V EYV G L+ +L + A G+ Y+H
Sbjct 397 IGYAATVDE--LFVVYEYVRKGMLKSHLHDPQSKGNTPLSWIMRNQIALDAARGLEYIHE 454
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
HY+HRD+ N+LLD KI DFGLAK V + E + APE L
Sbjct 455 HTKTHYVHRDIKTSNILLDEAFRAKISDFGLAKLVEKTGEGEISVTKVVGTYGYLAPEYL 514
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDS--------SQSPPTKFLELIGIA-----QGQMT 1120
+ SD+++FGV L+E+++ ++ +++P + L I +A M
Sbjct 515 SDGLATSKSDIYAFGVVLFEIISGREAVIRTEAIGTKNPERRPLASIMLAVLKNSPDSMN 574
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ L E ++ P C ++ L K C + + RP + ++ L +
Sbjct 575 MSSLKEFVDPNMMDLYPHDCLFKIATLAKQCVDDDPILRPNMKQVVISLSQI 626
Score = 206 bits (523), Expect = 2e-54, Method: Composition-based stats.
Identities = 76/330 (23%), Positives = 118/330 (36%), Gaps = 81/330 (25%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
R E + + LG G +VY G LR E V +K
Sbjct 335 RAATDEFSDSNLLGHGNYGSVYFGLLR--------------------------EQEVAVK 368
Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+ + F ++ +V H++L + G E +V EYV G L L
Sbjct 369 RMTATKT---KEFAAEMKVLCKVHHSNLVELIGYAATVDELFVVYEYVRKGMLKSHLHDP 425
Query 703 --RGHVPMAWKMV--VAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFI 755
+G+ P++W M +A A L Y+ + VH ++ NILL A
Sbjct 426 QSKGNTPLSWIMRNQIALDAARGLEYIHEHTKTHYVHRDIKTSNILLDEAFRA------- 478
Query 756 KLSDPGVGL-------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
K+SD G+ G +S + V +LAPE L G ++ D + FG L EI
Sbjct 479 KISDFGLAKLVEKTGEGEISVTKVVGTYGYLAPEYLSDGLA--TSKSDIYAFGVVLFEII 536
Query 809 FDGE----------------------------APLQSRSPSEKEHFYQRQHRLPEPSC-P 839
E +P S KE L C
Sbjct 537 SGREAVIRTEAIGTKNPERRPLASIMLAVLKNSPDSMNMSSLKEFVDPNMMDLYPHDCLF 596
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
++ATL QC+ +P RP+ + ++ L+++
Sbjct 597 KIATLAKQCVDDDPILRPNMKQVVISLSQI 626
>sp|O04534|LRK51_ARATH Putative L-type lectin-domain containing
receptor kinase V.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK51
PE=3 SV=1
Length=666
Score = 238 bits (607), Expect = 2e-65, Method: Composition-based stats.
Identities = 73/279 (26%), Positives = 122/279 (44%), Gaps = 16/279 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FGKV Y T + +AVK + D Q + EI + L H ++++
Sbjct 350 LGKGGFGKV----YKGTLPVSNVEIAVKMVSHD-SRQGMREFIAEIATIGRLRHPNLVRL 404
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018
+G C +GE L LV + + GSL +L ++ +Q + + G+ YLH Q
Sbjct 405 QGYCRHKGE--LYLVYDCMAKGSLDKFLYHQQTGNLDWSQRFKIIKDVASGLYYLHQQWV 462
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ N+LLD + K+GDFGLAK G + G + + +PE +
Sbjct 463 QVIIHRDIKPANILLDANMNAKLGDFGLAKLCDHGTDPQTSHVAG--TLGYISPELSRTG 520
Query 1077 KFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
K SDV++FG+ + E+ + + L + ++L+
Sbjct 521 KASTRSDVFAFGIVMLEIACGRKPILPRASQREMVLTDWVLECWENEDIMQVLDHKIGQE 580
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
++ V L C A+ RP ++I +L +V +
Sbjct 581 YVEEQAALVLKLGLFCSHPVAAIRPNMSSVIQLLDSVAQ 619
Score = 219 bits (558), Expect = 5e-59, Method: Composition-based stats.
Identities = 51/272 (19%), Positives = 95/272 (35%), Gaps = 43/272 (16%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
+ + K LG+G VY+G L V
Sbjct 329 PHRFAFKDLHIATKGFKDTEVLGKGGFGKVYKGTLPVSN--------------------- 367
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ + +K++ F + + ++ H +L + G C E +V + + G
Sbjct 368 ---VEIAVKMVSHDSRQGMREFIAEIATIGRLRHPNLVRLQGYCRHKGELYLVYDCMAKG 424
Query 694 PLDVWL-RRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAE 749
LD +L ++ G++ + + + + +AS L YL + ++H ++ NILL
Sbjct 425 SLDKFLYHQQTGNLDWSQRFKIIKDVASGLYYLHQQWVQVIIHRDIKPANILLD------ 478
Query 750 GTSPFIKLSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+ KL D G+ + +++PE G ST D + FG +
Sbjct 479 -ANMNAKLGDFGLAKLCDHGTDPQTSHVAGTLGYISPELSRTGKA--STRSDVFAFGIVM 535
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836
LEI G P+ R+ + E
Sbjct 536 LEIAC-GRKPILPRASQREMVLTDWVLECWEN 566
>sp|O22932|CIPKB_ARATH CBL-interacting serine/threonine-protein
kinase 11 OS=Arabidopsis thaliana OX=3702 GN=CIPK11 PE=1 SV=1
Length=435
Score = 231 bits (590), Expect = 2e-65, Method: Composition-based stats.
Identities = 65/270 (24%), Positives = 112/270 (41%), Gaps = 28/270 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC---GPQHRSGWKQEIDILRTLYHEHI 959
LG G F KV + + TG+ VAVK L P + K+EI I+R L H +I
Sbjct 27 LGCGAFAKV----FHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHPNI 82
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018
+K + + + ME+V G L + + +H + + QQ+ + Y HA+
Sbjct 83 VKLHEVMATKSK--IFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARG 140
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N+L+D + +K+ DFGL+ + + +P + APE L + +
Sbjct 141 VYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPA-YVAPEILSKKGY 199
Query 1079 -YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
DVWS G+ L+ L+ P V+ + + + +GE P
Sbjct 200 EGAKVDVWSCGIVLFVLVAGYLPFNDP---------------NVMNMYKKIYKGEYR-FP 243
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
++ + + R T + ++
Sbjct 244 RWMSPDLKRFVSRLLDINPETRITIDEILK 273
Score = 182 bits (463), Expect = 1e-48, Method: Composition-based stats.
Identities = 63/373 (17%), Positives = 116/373 (31%), Gaps = 51/373 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP- 646
+ LG G V+ RDR V +K+L+
Sbjct 20 KYELGKLLGCGAFAKVFHA------------------------RDRRTGQSVAVKILNKK 55
Query 647 ---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
++ +A S+M ++SH ++ +H V + E+V+ G L + +
Sbjct 56 KLLTNPALANNIKREISIMRRLSHPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKH- 114
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
G + QQL SA+ Y + + H ++ N+L+ G +K+SD G+
Sbjct 115 GRLSEDLSRRYFQQLISAVGYCHARGVYHRDLKPENLLIDENG-------NLKVSDFGLS 167
Query 764 LGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
++APE L +D W G L + G P
Sbjct 168 ALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYE-GAKVDVWSCGIVL-FVLVAGYLPFND 225
Query 818 RSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
+ + +R P P L S+ L P R + IL+D ++
Sbjct 226 PNVMNMYKKIYKGEYRFPRWMSPDLKRFVSRLLDINPETRITIDEILKDPWFVRGGFKQI 285
Query 877 VLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC 936
+ + DL G + ++ +GE +
Sbjct 286 KFHDDEIEDQKVESSLEAVKSLNAFDLISYSSGLDLSGLFAGCSNSSGES------ERFL 339
Query 937 GPQHRSGWKQEID 949
+ +E++
Sbjct 340 SEKSPEMLAEEVE 352
>sp|Q9FHG4|LRKS7_ARATH Probable L-type lectin-domain containing
receptor kinase S.7 OS=Arabidopsis thaliana OX=3702 GN=LECRKS7
PE=2 SV=1
Length=681
Score = 238 bits (607), Expect = 2e-65, Method: Composition-based stats.
Identities = 66/286 (23%), Positives = 128/286 (45%), Gaps = 20/286 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
R +G G FG V + +G + AVK + + + ++ + E+ I+ L H
Sbjct 365 FHSSRVIGRGAFGNVYRAMF----VSSGTISAVKRSRHNST-EGKTEFLAELSIIACLRH 419
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEG 1010
+++++ +G C ++GE L LV E++P GSL L + S + + L A +
Sbjct 420 KNLVQLQGWCNEKGE--LLLVYEFMPNGSLDKILYQESQTGAVALDWSHRLNIAIGLASA 477
Query 1011 MAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
++YLH Q +HRD+ N++LD + ++GDFGLA+ G + +
Sbjct 478 LSYLHHECEQQVVHRDIKTSNIMLDINFNARLGDFGLARLTEHDKSPVSTLTAG--TMGY 535
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT--KFLELIGIAQGQMTVLRLT 1125
APE L+ +D +S+GV + E+ P K + L+ + R+
Sbjct 536 LAPEYLQYGTATEKTDAFSYGVVILEVACGRRPIDKEPESQKTVNLVDWVWRLHSEGRVL 595
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
E ++ + ++ ++ + C +++ RP+ ++ IL
Sbjct 596 EAVDERLKGEFDEEMMKKLLLVGLKCAHPDSNERPSMRRVLQILNN 641
Score = 206 bits (524), Expect = 2e-54, Method: Composition-based stats.
Identities = 63/344 (18%), Positives = 118/344 (34%), Gaps = 65/344 (19%)
Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + S+ + K +G+G NVY G+
Sbjct 349 GLREFSYKELYTATKGFHSSRVIGRGAFGNVYRAMFVSSGTIS----------------- 391
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
+K + + F S+++ + H +L + G C E ++V E++ +
Sbjct 392 -------AVKRSRHNSTEGKTEFLAELSIIACLRHKNLVQLQGWCNEKGELLLVYEFMPN 444
Query 693 GPLDVWLRRERGH----VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARL 745
G LD L +E + + ++ +A LASALSYL + +VH ++ NI+L
Sbjct 445 GSLDKILYQESQTGAVALDWSHRLNIAIGLASALSYLHHECEQQVVHRDIKTSNIMLD-- 502
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800
+ +L D G+ + V + +LAPE L G + + D + +
Sbjct 503 -----INFNARLGDFGLARLTEHDKSPVSTLTAGTMGYLAPEYLQYG--TATEKTDAFSY 555
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP------------------EPSCPQLA 842
G +LE+ + + + RL E +L
Sbjct 556 GVVILEVACGRRPIDKEPESQKTVNLVDWVWRLHSEGRVLEAVDERLKGEFDEEMMKKLL 615
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
+ +C + +RPS R +L+ L + +
Sbjct 616 LVGLKCAHPDSNERPSMRRVLQILNNEIEPSPVPKMKPTLSFSC 659
>sp|Q8VYY5|NCRK_ARATH Receptor-like serine/threonine-protein kinase
NCRK OS=Arabidopsis thaliana OX=3702 GN=NCRK PE=1 SV=1
Length=565
Score = 235 bits (600), Expect = 2e-65, Method: Composition-based stats.
Identities = 74/326 (23%), Positives = 120/326 (37%), Gaps = 20/326 (6%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
L + + + + +G G V
Sbjct 175 CFFQNASLFCVSKPETIHGAIFQFSYTELEQATNKFSSNSVIGHGGSSCVYRGQLK---- 230
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL--QLVME 979
G+ A+K L G + + E+++L L+H H++ G C + K LV E
Sbjct 231 -DGKTAAIKRLNTPKGDDTDTLFSTEVELLSRLHHYHVVPLIGYCSEFHGKHAERLLVFE 289
Query 980 YVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDN 1033
Y+ GSLRD L + + A G+ YLH +HRD+ + N+LLD
Sbjct 290 YMSYGSLRDCLDGELGEKMTWNIRISVALGAARGLEYLHEAAAPRILHRDVKSTNILLDE 349
Query 1034 DRLVKIGDFGLAKAVPEG---HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
+ KI D G+AK + ++APE SDV+SFGV
Sbjct 350 NWHAKITDLGMAKCLSSDGLQSGSSSPTTGLQGTFGYFAPEYAIAGCASQMSDVFSFGVV 409
Query 1091 LYELLTHCDSSQSPP----TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
L EL+T Q P + L + + + Q + + EL + ++ + +
Sbjct 410 LLELITGRKPIQKPSNNKGEESLVIWAVPRLQDSKRVIEELPDPRLNGKFAEEEMQIMAY 469
Query 1147 LMKNCWETEASFRPTFENLIPILKTV 1172
L K C + RPT ++ IL T+
Sbjct 470 LAKECLLLDPESRPTMREVVQILSTI 495
Score = 195 bits (495), Expect = 2e-51, Method: Composition-based stats.
Identities = 69/366 (19%), Positives = 121/366 (33%), Gaps = 77/366 (21%)
Query 567 ARASPRTLNLSQLSFHRVD----QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
+ P T++ + F + + + S +G G + VY G+L+ +
Sbjct 184 CVSKPETIHGAIFQFSYTELEQATNKFSSNSVIGHGGSSCVYRGQLKDGKTA-------- 235
Query 623 DEDPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-- 679
+K L+ P D F L+S++ H H+ + G C
Sbjct 236 -----------------AIKRLNTPKGDDTDTLFSTEVELLSRLHHYHVVPLIGYCSEFH 278
Query 680 --GPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHG 733
E ++V EY+ +G L L E G + ++ VA A L YL ++H
Sbjct 279 GKHAERLLVFEYMSYGSLRDCLDGELGEKMTWNIRISVALGAARGLEYLHEAAAPRILHR 338
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR----------EERVERIPWLAPEC 783
+V NILL + K++D G+ S + APE
Sbjct 339 DVKSTNILLDE-------NWHAKITDLGMAKCLSSDGLQSGSSSPTTGLQGTFGYFAPEY 391
Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-------------- 829
G S D + FG LLE+ + + + +E
Sbjct 392 AIAGCA--SQMSDVFSFGVVLLELITGRKPIQKPSNNKGEESLVIWAVPRLQDSKRVIEE 449
Query 830 ------QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
+ E +A L +CL +P RP+ R +++ L+ + P + +
Sbjct 450 LPDPRLNGKFAEEEMQIMAYLAKECLLLDPESRPTMREVVQILSTITPDTSSRRRNFPIN 509
Query 884 SPASDP 889
Sbjct 510 YLFQSN 515
>sp|Q64725|KSYK_RAT Tyrosine-protein kinase SYK OS=Rattus norvegicus
OX=10116 GN=Syk PE=1 SV=1
Length=629
Score = 237 bits (604), Expect = 2e-65, Method: Composition-based stats.
Identities = 100/325 (31%), Positives = 147/325 (45%), Gaps = 23/325 (7%)
Query 851 YEPTQRPS--FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
YEPT R + R+ + + + + K + +LG G+F
Sbjct 317 YEPTGGAWGPDRGLQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDNELGSGNF 376
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
G V Y V + LK + P + E ++++ L + +I++ G CE
Sbjct 377 GTVKKGYYQMKKVVKTVAVKI--LKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICE 434
Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
+S LVME G L YL ++ I ++ Q+ GM YL +++HRDLAA
Sbjct 435 ---AESWMLVMEMAAWGPLNKYLQQNRHIKDKNIIELVHQVSMGMKYLEESNFVHRDLAA 491
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RNVLL KI DFGL+KA+ YY+ + G PV WYAPEC+ +KF SDVWS
Sbjct 492 RNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYFKFSSKSDVWS 551
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
FGV ++E ++ M +T +LE+GER+ P CP E+Y
Sbjct 552 FGVLMWEAFSYGQK--------------PYRGMKGSEVTAMLEKGERMGCPPGCPREMYD 597
Query 1147 LMKNCWETEASFRPTFENLIPILKT 1171
LM CW + RP F + L+
Sbjct 598 LMFLCWTYDVENRPGFAAVELRLRN 622
Score = 206 bits (524), Expect = 8e-55, Method: Composition-based stats.
Identities = 64/290 (22%), Positives = 113/290 (39%), Gaps = 40/290 (14%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ + LG G V +G +++ K+ + P LK
Sbjct 367 EDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDP----------ALK-------- 408
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
A++M Q+ + ++ + G+C ++V E GPL+ +L++ R H+
Sbjct 409 --DELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAAWGPLNKYLQQNR-HIKDKN 464
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ + Q++ + YLE N VH ++ RN+LL T + K+SD G+ + E
Sbjct 465 IIELVHQVSMGMKYLEESNFVHRDLAARNVLL-------VTQHYAKISDFGLSKALRADE 517
Query 771 ERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ + W APEC+ S+ D W FG + E G+ P + SE
Sbjct 518 NYYKAQTHGKWPVKWYAPECI--NYFKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEV 575
Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
++ R+ P ++ L C TY+ RP F + L
Sbjct 576 TAMLEKGERMGCPPGCPREMYDLMFLCWTYDVENRPGFAAVELRLRNYYY 625
Score = 35.8 bits (81), Expect = 2.7, Method: Composition-based stats.
Identities = 18/87 (21%), Positives = 30/87 (34%), Gaps = 12/87 (14%)
Query 453 GPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQ 509
G + + L DGLYL+ S ++ L+VA +A + IE+
Sbjct 17 GNITREEAEDYLVQGGMTDGLYLLRQSRNYLGGFALSVAHNRKA---------HHYTIER 67
Query 510 QDGAFVLEGWGRSFPSVRELGAALQGC 536
+ GR+ S +L
Sbjct 68 ELNGTYAISGGRAHASPADLCHYHSQE 94
>sp|Q54U31|SHKD_DICDI Dual specificity protein kinase shkD OS=Dictyostelium
discoideum OX=44689 GN=shkD PE=3 SV=1
Length=744
Score = 239 bits (611), Expect = 3e-65, Method: Composition-based stats.
Identities = 69/277 (25%), Positives = 120/277 (43%), Gaps = 31/277 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG+G FG V G+ VAVK K + ++ E+ I+ ++H +++
Sbjct 282 FLGQGSFGSVYKG------KCRGQEVAVKIPRKQKLSLYELTSFRHEVKIMSKIFHPNVV 335
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHA 1016
+ G C G+ +Q+V E L L + L + + A+ GM +LH
Sbjct 336 LFLGACTQSGK--MQIVTELCQ-TDLEKLLHNDRTKKEFSLFRRMQMAKDAALGMNWLHG 392
Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+H DL N+L+D + VK+ DFG + + EG E+ + W APE +
Sbjct 393 ITRIVHNDLKTANLLVDINLRVKVTDFGFS-QIKEGEEFQD--KAAKGTPLWMAPEVMMG 449
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ +DV+SFG+ L+E+LT ++P + + + + ER P
Sbjct 450 NPYNEKADVYSFGIILWEILT----KEAPYSHHKDY---------DIFFNAICNEKERPP 496
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P + HL++ CW+ RP+F ++ L +
Sbjct 497 IPADTLPSLRHLIQTCWDHNPQNRPSFSEILFRLNEI 533
Score = 216 bits (550), Expect = 2e-57, Method: Composition-based stats.
Identities = 74/386 (19%), Positives = 128/386 (33%), Gaps = 56/386 (15%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ +EI + LGQG+ +VY+G+ R GQE+ V +
Sbjct 270 PEILPEEIDRTDFLGQGSFGSVYKGKCR------------------------GQEVAVKI 305
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
+F +MS++ H ++ G C + + +VTE + L+ L
Sbjct 306 PRKQKLSLYELTSFRHEVKIMSKIFHPNVVLFLGACTQSGKMQIVTELCQ-TDLEKLLHN 364
Query 702 ER--GHVPMAWKMVVAQQLASALSYLEN-KNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+R + +M +A+ A +++L +VH ++ N+L+ + +K++
Sbjct 365 DRTKKEFSLFRRMQMAKDAALGMNWLHGITRIVHNDLKTANLLVD-------INLRVKVT 417
Query 759 DPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
D G + W+APE + G N + D + FG L EI EAP
Sbjct 418 DFGFSQIKEGEEFQDKAAKGTPLWMAPEVMMG--NPYNEKADVYSFGIILWEILTK-EAP 474
Query 815 LQSRSPSEKEH--FYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ + R +P + P L L C + P RPSF IL L +
Sbjct 475 YSHHKDYDIFFNAICNEKERPPIPADTLPSLRHLIQTCWDHNPQNRPSFSEILFRLNEIL 534
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA-V 929
D + + T+ A +
Sbjct 535 IDCAIDFDDGRKYWKEHFLVPKQELQEEVEWSD--------FEKTLKATHKQLNLDYAPL 586
Query 930 KALKADCGPQHRSGWKQEIDILRTLY 955
K L Q KQ + +
Sbjct 587 KELLVQQSHQTVQKTKQ-VVTMERFD 611
>sp|Q3SWY6|STK25_BOVIN Serine/threonine-protein kinase 25 OS=Bos
taurus OX=9913 GN=STK25 PE=2 SV=1
Length=426
Score = 231 bits (588), Expect = 3e-65, Method: Composition-based stats.
Identities = 72/290 (25%), Positives = 123/290 (42%), Gaps = 24/290 (8%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ V + K+ +G+G FG+V Y ++ T E+VA+K + +
Sbjct 1 MAHLRGFANQHSRVDPEELFTKLDRIGKGSFGEV----YKGIDNRTKEVVAIKIIDLEEA 56
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL 997
+QEI +L +I +Y G + L ++MEY+ GS D L +
Sbjct 57 EDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTK--LWIIMEYLGGGSALDLLKPGPLEE 114
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ ++I +G+ YLH++ IHRD+ A NVLL VK+ DFG+A + +
Sbjct 115 TYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD---TQIK 171
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
R FW APE +K+ + + +D+WS G+T EL + PP
Sbjct 172 RNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIEL-----AKGEPP----------NS 216
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ +R+ L+ + ++ C + FRPT + L+
Sbjct 217 DLHPMRVLFLIPKNSPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLK 266
Score = 202 bits (513), Expect = 3e-55, Method: Composition-based stats.
Identities = 60/297 (20%), Positives = 110/297 (37%), Gaps = 44/297 (15%)
Query 583 RVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
RVD +E T+L +G+G+ VY+G D + V +
Sbjct 13 RVDPEELFTKLDRIGKGSFGEVYKGI------------------------DNRTKEVVAI 48
Query 642 KVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K++D D + +++SQ ++ G ++ + ++ EY+ G L+
Sbjct 49 KIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLK 108
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G + + + +++ L YL ++ +H ++ N+LL+ G +KL+D
Sbjct 109 --PGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGD-------VKLADF 159
Query 761 GVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
GV + R V W+APE + A D W G T +E+ GE P
Sbjct 160 GVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDF--KADIWSLGITAIELA-KGEPPNS 216
Query 817 SRSPSEKEHFYQRQ--HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P + L CL +P RP+ + +L+ +
Sbjct 217 DLHPMRVLFLIPKNSPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRY 273
>sp|Q9SZD5|LRK59_ARATH L-type lectin-domain containing receptor
kinase V.9 OS=Arabidopsis thaliana OX=3702 GN=LECRK59 PE=2
SV=1
Length=669
Score = 238 bits (606), Expect = 3e-65, Method: Composition-based stats.
Identities = 82/282 (29%), Positives = 125/282 (44%), Gaps = 20/282 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FGKV Y T + +AVK + D Q + EI + L H ++++
Sbjct 350 LGKGGFGKV----YKGTLSTSNMDIAVKKVSHD-SRQGMREFVAEIATIGRLRHPNLVRL 404
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018
G C +GE L LV + +P GSL +L P S+ +Q + + G+ YLH Q
Sbjct 405 LGYCRRKGE--LYLVYDCMPKGSLDKFLYHQPEQSLDWSQRFKIIKDVASGLCYLHHQWV 462
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ NVLLD+ K+GDFGLAK G + + + +PE +
Sbjct 463 QVIIHRDIKPANVLLDDSMNGKLGDFGLAKLCEHGFDPQT--SNVAGTFGYISPELSRTG 520
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
K +SDV++FG+ + E+ T P + + + L ER+ +
Sbjct 521 KASTSSDVFAFGILMLEI-TCGRRPVLPRASSPSEMVLTDWVLDCWEDDILQVVDERVKQ 579
Query 1137 PDKCPCE----VYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
DK E V L C A+ RP+ ++I L V +
Sbjct 580 DDKYLEEQVALVLKLGLFCSHPVAAVRPSMSSVIQFLDGVAQ 621
Score = 218 bits (554), Expect = 2e-58, Method: Composition-based stats.
Identities = 55/280 (20%), Positives = 95/280 (34%), Gaps = 61/280 (22%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ K LG+G VY+G L + + +K
Sbjct 339 IATKGFRNSELLGKGGFGKVYKGTLSTSN------------------------MDIAVKK 374
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL-RRE 702
+ F + + ++ H +L + G C R E +V + + G LD +L +
Sbjct 375 VSHDSRQGMREFVAEIATIGRLRHPNLVRLLGYCRRKGELYLVYDCMPKGSLDKFLYHQP 434
Query 703 RGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ + + + + +AS L YL + + ++H ++ N+LL S KL D
Sbjct 435 EQSLDWSQRFKIIKDVASGLCYLHHQWVQVIIHRDIKPANVLLD-------DSMNGKLGD 487
Query 760 PGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ +++PE G ST+ D + FG +LEI G P
Sbjct 488 FGLAKLCEHGFDPQTSNVAGTFGYISPELSRTGKA--STSSDVFAFGILMLEI-TCGRRP 544
Query 815 LQSR--SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYE 852
+ R SPSE L C +
Sbjct 545 VLPRASSPSEMV----------------LTDWVLDCWEDD 568
>sp|C0LGQ5|GSO1_ARATH LRR receptor-like serine/threonine-protein
kinase GSO1 OS=Arabidopsis thaliana OX=3702 GN=GSO1 PE=1
SV=1
Length=1249
Score = 246 bits (627), Expect = 3e-65, Method: Composition-based stats.
Identities = 73/315 (23%), Positives = 124/315 (39%), Gaps = 22/315 (7%)
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931
H + + + L + +G G GKV + GE VAVK
Sbjct 926 HKPLFRNGASKSDIRWEDIMEATHNLSEEFMIGSGGSGKVYKAELE-----NGETVAVKK 980
Query 932 LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP 991
+ + +E+ L + H H++K G C + E L+ EY+ GS+ D+L
Sbjct 981 ILWKDDLMSNKSFSREVKTLGRIRHRHLVKLMGYCSSKSEGLNLLIYEYMKNGSIWDWLH 1040
Query 992 RHS---------IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKI 1039
+ L A + +G+ YLH +HRD+ + NVLLD++ +
Sbjct 1041 EDKPVLEKKKKLLDWEARLRIAVGLAQGVEYLHHDCVPPIVHRDIKSSNVLLDSNMEAHL 1100
Query 1040 GDFGLAKAVPEGHEYYR-VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
GDFGLAK + E + + APE K SDV+S G+ L E++T
Sbjct 1101 GDFGLAKVLTENCDTNTDSNTWFACSYGYIAPEYAYSLKATEKSDVYSMGIVLMEIVTGK 1160
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLT--ELLERGERLPRP--DKCPCEVYHLMKNCWET 1154
+ S ++++ + + V +L++ + P + C+V + C +T
Sbjct 1161 MPTDSVFGAEMDMVRWVETHLEVAGSARDKLIDPKLKPLLPFEEDAACQVLEIALQCTKT 1220
Query 1155 EASFRPTFENLIPIL 1169
RP+ L
Sbjct 1221 SPQERPSSRQACDSL 1235
Score = 186 bits (472), Expect = 2e-46, Method: Composition-based stats.
Identities = 60/340 (18%), Positives = 116/340 (34%), Gaps = 77/340 (23%)
Query 577 SQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
S + + + +++ +G G VY+ L + G
Sbjct 937 SDIRWEDIMEATHNLSEEFMIGSGGSGKVYKAEL-----------------------ENG 973
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEH 692
+ + V K+L +F + ++ H HL + G C E N+++ EY+++
Sbjct 974 ETVAVK-KILWKDDLMSNKSFSREVKTLGRIRHRHLVKLMGYCSSKSEGLNLLIYEYMKN 1032
Query 693 GPLDVWLR-------RERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILL 742
G + WL +++ + ++ +A LA + YL + +VH ++ N+LL
Sbjct 1033 GSIWDWLHEDKPVLEKKKKLLDWEARLRIAVGLAQGVEYLHHDCVPPIVHRDIKSSNVLL 1092
Query 743 ARLGLAEGTSPFIKLSDPGVGL--------GALSREERVERIPWLAPECLPGGANSLSTA 794
++ L D G+ S ++APE + +
Sbjct 1093 D-------SNMEAHLGDFGLAKVLTENCDTNTDSNTWFACSYGYIAPEYA--YSLKATEK 1143
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--------------------- 833
D + G L+EI G+ P S +E + + L
Sbjct 1144 SDVYSMGIVLMEIV-TGKMPTDSVFGAEMDMVRWVETHLEVAGSARDKLIDPKLKPLLPF 1202
Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
E + Q+ + QC P +RPS R L + +
Sbjct 1203 EEDAACQVLEIALQCTKTSPQERPSSRQACDSLLHVYNNR 1242
>sp|Q1HKZ5|M3K13_MOUSE Mitogen-activated protein kinase kinase
kinase 13 OS=Mus musculus OX=10090 GN=Map3k13 PE=1 SV=1
Length=959
Score = 243 bits (620), Expect = 3e-65, Method: Composition-based stats.
Identities = 83/301 (28%), Positives = 122/301 (41%), Gaps = 35/301 (12%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ + + + D + +++ LG G G V L + E VA+K
Sbjct 141 WNIIGKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRA------EEVAIK 194
Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
++ I LR L H +II +KG C ++MEY G L + L
Sbjct 195 KVREQNETD--------IKHLRKLKHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVL 244
Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
I L+ ++ I GM YLH IHRDL + NVL+ + VKI DFG +K +
Sbjct 245 RAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELS 304
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
+ + V W APE ++ D+WSFGV L+ELLT P K +
Sbjct 305 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG-----EIPYKDV 355
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ I G + LP P CP LMK W+++ RP+F + L
Sbjct 356 DSSAIIWGVGSN---------SLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHL 406
Query 1170 K 1170
Sbjct 407 D 407
Score = 216 bits (550), Expect = 2e-56, Method: Composition-based stats.
Identities = 65/305 (21%), Positives = 109/305 (36%), Gaps = 50/305 (16%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+A L Q V +EI++L LG G + V+ G+ R E
Sbjct 145 GKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAE--------------- 189
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
V +K + + + ++ H ++ GVC + P ++
Sbjct 190 -----------EVAIKKVREQNE-------TDIKHLRKLKHPNIIAFKGVCTQAPCYCII 231
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
EY HG L LR R + + + +AS ++YL ++H ++ N+L+
Sbjct 232 MEYCAHGQLYEVLRAGR-KITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTD 290
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+K+SD G + ++ + W+APE + +S +D W FG
Sbjct 291 A-------VKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 341
Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
L E+ GE P + S +P L Q +P RPSFR
Sbjct 342 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFR 400
Query 861 TILRD 865
L
Sbjct 401 QTLMH 405
>sp|Q9LDT0|CRK30_ARATH Putative cysteine-rich receptor-like protein
kinase 30 OS=Arabidopsis thaliana OX=3702 GN=CRK30 PE=3
SV=1
Length=700
Score = 238 bits (608), Expect = 3e-65, Method: Composition-based stats.
Identities = 72/296 (24%), Positives = 112/296 (38%), Gaps = 21/296 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G+G FG+V G VAVK L Q +K E+ ++ L H +++
Sbjct 350 NKIGQGGFGEVYKGTL-----SNGTEVAVKRLSR-TSDQGELEFKNEVLLVAKLQHRNLV 403
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEGMAY 1013
+ G QGE+ + LV E+VP SL +L + + + I G+ Y
Sbjct 404 RLLG-FALQGEEKI-LVFEFVPNKSLDYFLFGSTNPTKKGQLDWTRRYNIIGGITRGLLY 461
Query 1014 LHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
LH IHRD+ A N+LLD D KI DFG+A+ + H+ + P
Sbjct 462 LHQDSRLTIIHRDIKASNILLDADMNPKIADFGMARNFRD-HQTEDSTGRVVGTFGYMPP 520
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
E + +F SDV+SFGV + E+++ S L+ EL+
Sbjct 521 EYVAHGQFSTKSDVYSFGVLILEIVSGRKNSSFYQMDGSVCNLVTYVWRLWNTDSSLELV 580
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
+ H+ C + RP + +L P F
Sbjct 581 DPAISGSYEKDEVTRCIHIGLLCVQENPVNRPALSTIFQMLTNSSITLNVPQPPGF 636
Score = 229 bits (583), Expect = 5e-62, Method: Composition-based stats.
Identities = 59/327 (18%), Positives = 107/327 (33%), Gaps = 68/327 (21%)
Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
T+ Q ++ + +GQG VY+G L
Sbjct 328 TVGYLQFDIKDIEAATSNFLASNKIGQGGFGEVYKGTLSNG------------------- 368
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
V +K L + L F L++++ H +L + G ++G E I+V E+V
Sbjct 369 ------TEVAVKRLSRTSDQGELEFKNEVLLVAKLQHRNLVRLLGFALQGEEKILVFEFV 422
Query 691 EHGPLDVWLRR-----ERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILL 742
+ LD +L ++G + + + + L YL + ++H ++ NILL
Sbjct 423 PNKSLDYFLFGSTNPTKKGQLDWTRRYNIIGGITRGLLYLHQDSRLTIIHRDIKASNILL 482
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMD 796
K++D G+ + V ++ PE + G ST D
Sbjct 483 D-------ADMNPKIADFGMARNFRDHQTEDSTGRVVGTFGYMPPEYVAHG--QFSTKSD 533
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC------------------ 838
+ FG +LEI + + + RL
Sbjct 534 VYSFGVLILEIVSGRKNSSFYQMDGSVCNLVTYVWRLWNTDSSLELVDPAISGSYEKDEV 593
Query 839 PQLATLTSQCLTYEPTQRPSFRTILRD 865
+ + C+ P RP+ TI +
Sbjct 594 TRCIHIGLLCVQENPVNRPALSTIFQM 620
>sp|Q9Z2W1|STK25_MOUSE Serine/threonine-protein kinase 25 OS=Mus
musculus OX=10090 GN=Stk25 PE=1 SV=2
Length=426
Score = 231 bits (588), Expect = 3e-65, Method: Composition-based stats.
Identities = 72/290 (25%), Positives = 123/290 (42%), Gaps = 24/290 (8%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ V + K+ +G+G FG+V Y ++ T E+VA+K + +
Sbjct 1 MAHLRGFAHQHSRVDPEELFTKLDRIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEA 56
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL 997
+QEI +L +I +Y G + L ++MEY+ GS D L +
Sbjct 57 EDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTK--LWIIMEYLGGGSALDLLKPGPLEE 114
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ ++I +G+ YLH++ IHRD+ A NVLL VK+ DFG+A + +
Sbjct 115 TYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD---TQIK 171
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
R FW APE +K+ + + +D+WS G+T EL + PP
Sbjct 172 RNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIEL-----AKGEPP----------NS 216
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ +R+ L+ + ++ C + FRPT + L+
Sbjct 217 DLHPMRVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLK 266
Score = 201 bits (511), Expect = 5e-55, Method: Composition-based stats.
Identities = 60/297 (20%), Positives = 111/297 (37%), Gaps = 44/297 (15%)
Query 583 RVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
RVD +E T+L +G+G+ VY+G D + V +
Sbjct 13 RVDPEELFTKLDRIGKGSFGEVYKGI------------------------DNHTKEVVAI 48
Query 642 KVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K++D D + +++SQ ++ G ++ + ++ EY+ G L+
Sbjct 49 KIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLK 108
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G + + + +++ L YL ++ +H ++ N+LL+ G +KL+D
Sbjct 109 --PGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGD-------VKLADF 159
Query 761 GVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
GV + R V W+APE + A D W G T +E+ GE P
Sbjct 160 GVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDF--KADIWSLGITAIELA-KGEPPNS 216
Query 817 SRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P + + L CL +P RP+ + +L+ +
Sbjct 217 DLHPMRVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRY 273
>sp|Q9M092|WAKLM_ARATH Wall-associated receptor kinase-like 17
OS=Arabidopsis thaliana OX=3702 GN=WAKL17 PE=3 SV=2
Length=786
Score = 240 bits (612), Expect = 3e-65, Method: Composition-based stats.
Identities = 72/281 (26%), Positives = 116/281 (41%), Gaps = 22/281 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G G V G VAVK K + E+ IL + H H++K
Sbjct 450 LGHGGQGTVYKGML-----VDGRTVAVKKSKV-IDEDKLQEFINEVVILSQINHRHVVKL 503
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-----LAQLLLFAQQICEGMAYLHA- 1016
GCC + E + LV E++ G+L ++ L A I ++YLH+
Sbjct 504 LGCCLE-TEVPI-LVYEFIINGNLFKHIHEEEADDYTMIWGMRLRIAVDIAGALSYLHSA 561
Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
HRD+ + N+LLD K+ DFG +++V ++ V + PE +
Sbjct 562 ASSPIYHRDIKSTNILLDEKYRAKVADFGTSRSVTIDQTHWTT--VISGTVGYVDPEYYR 619
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG---QMTVLRLTELLERG 1131
++ SDV+SFGV L EL+T D E+I +A+ M RL+++++
Sbjct 620 SSQYTEKSDVYSFGVILAELITG-DKPVIMVQNTQEIIALAEHFRVAMKERRLSDIMDAR 678
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
R + V +L C + RP + L+ +
Sbjct 679 IRDDSKPEQVMAVANLAMKCLSSRGRNRPNMREVFTELERI 719
Score = 219 bits (559), Expect = 2e-58, Method: Composition-based stats.
Identities = 68/342 (20%), Positives = 123/342 (36%), Gaps = 68/342 (20%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
L +G R +L + ++ LG G + VY+G L +
Sbjct 416 QQELNTRQGVVEKARIFTSKELEK---ATENFSENRVLGHGGQGTVYKGMLVDGRT---- 468
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
V +K D F ++SQ++H H+ + G C
Sbjct 469 ---------------------VAVKKSKVIDEDKLQEFINEVVILSQINHRHVVKLLGCC 507
Query 678 VRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAW--KMVVAQQLASALSYLE---NKNLV 731
+ I+V E++ +G L + E M W ++ +A +A ALSYL + +
Sbjct 508 LETEVPILVYEFIINGNLFKHIHEEEADDYTMIWGMRLRIAVDIAGALSYLHSAASSPIY 567
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPG 786
H ++ NILL A K++D G + + ++ PE
Sbjct 568 HRDIKSTNILLDEKYRA-------KVADFGTSRSVTIDQTHWTTVISGTVGYVDPEYYR- 619
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-----EHFY--QRQHRLPEPSC- 838
++ + D + FG L E+ G+ P+ +++ EHF ++ RL +
Sbjct 620 -SSQYTEKSDVYSFGVILAELI-TGDKPVIMVQNTQEIIALAEHFRVAMKERRLSDIMDA 677
Query 839 -----------PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+A L +CL+ RP+ R + +L R+
Sbjct 678 RIRDDSKPEQVMAVANLAMKCLSSRGRNRPNMREVFTELERI 719
>sp|Q8W1D5|CIPKP_ARATH CBL-interacting serine/threonine-protein
kinase 25 OS=Arabidopsis thaliana OX=3702 GN=CIPK25 PE=2 SV=1
Length=488
Score = 233 bits (593), Expect = 3e-65, Method: Composition-based stats.
Identities = 64/301 (21%), Positives = 118/301 (39%), Gaps = 26/301 (9%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
H + + + R LG+G FGKV TGE VA+K
Sbjct 17 FHPDSRYQSAPTMEEEQQQLRVLFAKYEMGRLLGKGTFGKVYYG----KEITTGESVAIK 72
Query 931 ALKADCGPQH--RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+ D + K+EI I+R + H +I++ K + + + +MEYV G L
Sbjct 73 IINKDQVKREGMMEQIKREISIMRLVRHPNIVELKEVMATKTK--IFFIMEYVKGGELFS 130
Query 989 YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ + + + QQ+ + + H++ HRDL N+L+D + +K+ DFGL+
Sbjct 131 KIVKGKLKEDSARKYFQQLISAVDFCHSRGVSHRDLKPENLLVDENGDLKVSDFGLSALP 190
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ + + +P + APE L++ + D+WS G+ LY LL Q
Sbjct 191 EQILQDGLLHTQCGTPA-YVAPEVLRKKGYDGAKGDIWSCGIILYVLLAGFLPFQDE--- 246
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
++++ + + E P E L+ + + R + ++
Sbjct 247 ------------NLMKMYRKIFKSE-FEYPPWFSPESKRLISKLLVVDPNKRISIPAIMR 293
Query 1168 I 1168
Sbjct 294 T 294
Score = 183 bits (465), Expect = 3e-48, Method: Composition-based stats.
Identities = 54/295 (18%), Positives = 96/295 (33%), Gaps = 43/295 (15%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
RV + LG+GT VY G+ G V +K
Sbjct 37 RVLFAKYEMGRLLGKGTFGKVYYGKEITTGES------------------------VAIK 72
Query 643 VLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+++ + S+M V H ++ + V + + EYV+ G L +
Sbjct 73 IINKDQVKREGMMEQIKREISIMRLVRHPNIVELKEVMATKTKIFFIMEYVKGGELFSKI 132
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+G + QQL SA+ + ++ + H ++ N+L+ G +K+SD
Sbjct 133 --VKGKLKEDSARKYFQQLISAVDFCHSRGVSHRDLKPENLLVDENGD-------LKVSD 183
Query 760 PGVGLGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ + ++APE L D W G L +
Sbjct 184 FGLSALPEQILQDGLLHTQCGTPAYVAPEVLRKKGYD-GAKGDIWSCGIILYVLLAGFLP 242
Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
++ + P P+ L S+ L +P +R S I+R
Sbjct 243 FQDENLMKMYRKIFKSEFEYPPWFSPESKRLISKLLVVDPNKRISIPAIMRTPWF 297
>sp|Q9XIC7|SERK2_ARATH Somatic embryogenesis receptor kinase 2
OS=Arabidopsis thaliana OX=3702 GN=SERK2 PE=1 SV=1
Length=628
Score = 236 bits (603), Expect = 3e-65, Method: Composition-based stats.
Identities = 69/325 (21%), Positives = 125/325 (38%), Gaps = 20/325 (6%)
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916
R + +V + LG G FGKV
Sbjct 265 WRRRKPQEFFFDVPAEEDPEVHLGQLKRFSLRELQVATDSFSNKNILGRGGFGKVYKGRL 324
Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976
G +VAVK LK + P ++ E++++ H ++++ +G C E+ L
Sbjct 325 -----ADGTLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTER--LL 377
Query 977 VMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028
V Y+ GS+ L + + A G++YLH IHRD+ A N
Sbjct 378 VYPYMANGSVASCLRERPPSQLPLAWSIRQQIALGSARGLSYLHDHCDPKIIHRDVKAAN 437
Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
+LLD + +GDFGLA+ + + V + APE L K +DV+ +G
Sbjct 438 ILLDEEFEAVVGDFGLARLMDYKDTH--VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 495
Query 1089 VTLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
+ L EL+T + + + L+ +G + +L L++ + + ++
Sbjct 496 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEMLVDPDLQSNYTEAEVEQLI 555
Query 1146 HLMKNCWETEASFRPTFENLIPILK 1170
+ C ++ RP ++ +L+
Sbjct 556 QVALLCTQSSPMERPKMSEVVRMLE 580
Score = 199 bits (506), Expect = 1e-52, Method: Composition-based stats.
Identities = 70/324 (22%), Positives = 111/324 (34%), Gaps = 67/324 (21%)
Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + S V + + LG+G VY+GRL
Sbjct 289 QLKRFSLRELQVATDSFSNKNILGRGGFGKVYKGRLADG--------------------- 327
Query 633 RGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
V +K L L F ++S H +L + G C+ E ++V Y+
Sbjct 328 ----TLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMA 383
Query 692 HGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745
+G + LR R +P+AW + +A A LSYL + ++H +V NILL
Sbjct 384 NGSVASCLRERPPSQLPLAWSIRQQIALGSARGLSYLHDHCDPKIIHRDVKAANILLDEE 443
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800
A + D G+ ++ V I +APE L G + S D +G+
Sbjct 444 FEAV-------VGDFGLARLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 494
Query 801 GATLLEICFDGEAPLQSR--SPSEKEHFYQRQHRLPEPSCPQLAT--------------- 843
G LLE+ A +R + + + L E L
Sbjct 495 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEMLVDPDLQSNYTEAEVEQL 554
Query 844 --LTSQCLTYEPTQRPSFRTILRD 865
+ C P +RP ++R
Sbjct 555 IQVALLCTQSSPMERPKMSEVVRM 578
>sp|Q9FXF2|RKF1_ARATH Probable LRR receptor-like serine/threonine-protein
kinase RFK1 OS=Arabidopsis thaliana OX=3702 GN=RKF1
PE=1 SV=1
Length=1021
Score = 243 bits (621), Expect = 3e-65, Method: Composition-based stats.
Identities = 72/322 (22%), Positives = 124/322 (39%), Gaps = 19/322 (6%)
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920
+ + + F +GEG FG V
Sbjct 645 ICGCLPRCGRQRKDPYEEELPSGTFTLRQIKFATDDFNPTNKIGEGGFGAVFKGVL---- 700
Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
G +VAVK L + +R + EI + L H +++K G C ++ + L L EY
Sbjct 701 -ADGRVVAVKQLSSKSRQGNRE-FLNEIGAISCLQHPNLVKLHGFCVERAQ--LLLAYEY 756
Query 981 VPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLD 1032
+ SL L + + I +G+A+LH + ++HRD+ A N+LLD
Sbjct 757 MENNSLSSALFSPKHKQIPMDWPTRFKICCGIAKGLAFLHEESPLKFVHRDIKATNILLD 816
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
D KI DFGLA+ E + + G + + APE + +DV+SFGV +
Sbjct 817 KDLTPKISDFGLARLDEEEKTHISTKVAG--TIGYMAPEYALWGYLTFKADVYSFGVLVL 874
Query 1093 ELLTHCDSSQSPPTKFLE-LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
E++ +S L+ A + L ++++ R K V + C
Sbjct 875 EIVAGITNSNFMGAGDSVCLLEFANECVESGHLMQVVDERLRPEVDRKEAEAVIKVALVC 934
Query 1152 WETEASFRPTFENLIPILKTVH 1173
+ RP ++ +L+ ++
Sbjct 935 SSASPTDRPLMSEVVAMLEGLY 956
Score = 220 bits (561), Expect = 1e-57, Method: Composition-based stats.
Identities = 64/326 (20%), Positives = 107/326 (33%), Gaps = 67/326 (21%)
Query 494 PDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLP 553
D R + GA++ G G L +L C L RC
Sbjct 608 SDSKPCERPK---TGMSPGAYIAIGIGAP---------CLIIFILGFLWICGCLPRCGRQ 655
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
+ + T L Q+ F + + +G+G V++G L
Sbjct 656 RKDPYEEEL-------PSGTFTLRQIKF---ATDDFNPTNKIGEGGFGAVFKGVLADGR- 704
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
V +K L F +S + H +L +
Sbjct 705 ------------------------VVAVKQLSSKSRQGNREFLNEIGAISCLQHPNLVKL 740
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAW--KMVVAQQLASALSYLENK-- 728
HG CV + ++ EY+E+ L L + +PM W + + +A L++L +
Sbjct 741 HGFCVERAQLLLAYEYMENNSLSSALFSPKHKQIPMDWPTRFKICCGIAKGLAFLHEESP 800
Query 729 -NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPE 782
VH ++ NILL + K+SD G+ + + I ++APE
Sbjct 801 LKFVHRDIKATNILLDKDLTP-------KISDFGLARLDEEEKTHISTKVAGTIGYMAPE 853
Query 783 CLPGGANSLSTAMDKWGFGATLLEIC 808
G + D + FG +LEI
Sbjct 854 YALWGYLTF--KADVYSFGVLVLEIV 877
>sp|P00531|MIL_AVIMH Serine/threonine-protein kinase-transforming
protein mil OS=Avian retrovirus MH2 OX=11870 GN=V-MIL PE=3
SV=1
Length=380
Score = 229 bits (583), Expect = 3e-65, Method: Composition-based stats.
Identities = 79/333 (24%), Positives = 134/333 (40%), Gaps = 35/333 (11%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
+ T P+ R + + +S + +G G F
Sbjct 38 WSQPKTPVPAQRERAPG----TNTQEKNKIRPRGQRDSSYYWEIEASEVLLSTRIGSGSF 93
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
G V + VAVK LK D P+ ++ E+ +LR H +I+ + G
Sbjct 94 GTVYKGKWHG-------DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYM- 145
Query 968 DQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
+ +L +V ++ SL +L + QL+ A+Q +GM YLHA++ IHRD+
Sbjct 146 --TKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMK 203
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYAS 1082
+ N+ L VKIGDFGLA +V E + W APE ++ F + S
Sbjct 204 SNNIFLHGGLTVKIGDFGLATVKSRWSGSQQV-EQPTGSILWMAPEVIRMQDSNPFSFQS 262
Query 1083 DVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
DV+S+G+ LYEL+T + + ++G + +L + C
Sbjct 263 DVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYK------------NC 310
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
P + L+ +C + RP F ++ + +
Sbjct 311 PKAMKRLVADCLKKVREERPLFPQILSSIALLQ 343
Score = 220 bits (560), Expect = 4e-62, Method: Composition-based stats.
Identities = 71/367 (19%), Positives = 127/367 (35%), Gaps = 62/367 (17%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
R + N I RG R S + ++ E+ + +G G+ VY+G+
Sbjct 49 RERAPGTNTQEKNKIRPRGQRDSSY--------YWEIEASEVLLSTRIGSGSFGTVYKGK 100
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQ 664
+ V +K+L DP+ AF +++ +
Sbjct 101 WHGD---------------------------VAVKILKVVDPTPEQFQ-AFRNEVAVLRK 132
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
H ++ G + +VT++ E L L + M + +A+Q A + Y
Sbjct 133 TRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 191
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778
L KN++H ++ NI L +K+ D G+ G+ E+ I W
Sbjct 192 LHAKNIIHRDMKSNNIFL-------HGGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILW 244
Query 779 LAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------ 831
+APE + +N S D + +G L E+ GE P + ++ F +
Sbjct 245 MAPEVIRMQDSNPFSFQSDVYSYGIVLYELM-TGELPYSHINNRDQIIFMVGRGYASPDL 303
Query 832 -RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
+L + + L + CL +RP F IL + LQ + + S
Sbjct 304 SKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSIALLQHSLPKINRSASEPSLHRASH 363
Query 891 VFHKRYL 897
Sbjct 364 TEDINSC 370
>sp|Q942F3|BRI1_ORYSJ Brassinosteroid LRR receptor kinase BRI1
OS=Oryza sativa subsp. japonica OX=39947 GN=BRI1 PE=1 SV=1
Length=1121
Score = 244 bits (624), Expect = 4e-65, Method: Composition-based stats.
Identities = 73/288 (25%), Positives = 123/288 (43%), Gaps = 21/288 (7%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+G G FG V G++VA+K L G R + E++ + + H
Sbjct 807 FHIACQIGSGGFGDVYKAQLK-----DGKVVAIKKLIHVSGQGDRE-FTAEMETIGKIKH 860
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGM 1011
+++ G C+ E+ LV +Y+ GSL D L + A G+
Sbjct 861 RNLVPLLGYCKAGEER--LLVYDYMKFGSLEDVLHDRKKIGKKLNWEARRKIAVGAARGL 918
Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
A+LH H IHRD+ + NVL+D ++ DFG+A+ + + V +P +
Sbjct 919 AFLHHNCIPHIIHRDMKSSNVLIDEQLEARVSDFGMARLMSVVDTHLSVSTLAGTP-GYV 977
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLRLTEL 1127
PE + ++ DV+S+GV L ELLT + S + L+G + Q T L++T++
Sbjct 978 PPEYYQSFRCTTKGDVYSYGVVLLELLTGKPPTDSADFGEDNNLVGWVK-QHTKLKITDV 1036
Query 1128 LERGERLPRPDKCPCEVYHL--MKNCWETEASFRPTFENLIPILKTVH 1173
+ P + HL C + S RPT ++ + K +
Sbjct 1037 FDPELLKEDPSVELELLEHLKIACACLDDRPSRRPTMLKVMAMFKEIQ 1084
Score = 207 bits (528), Expect = 2e-53, Method: Composition-based stats.
Identities = 53/317 (17%), Positives = 108/317 (34%), Gaps = 66/317 (21%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+G G +VY+ +L+ V +K L
Sbjct 803 ATNGFHIACQIGSGGFGDVYKAQLKDGK-------------------------VVAIKKL 837
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER- 703
F + ++ H +L + G C G E ++V +Y++ G L+ L +
Sbjct 838 IHVSGQGDREFTAEMETIGKIKHRNLVPLLGYCKAGEERLLVYDYMKFGSLEDVLHDRKK 897
Query 704 --GHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ + +A A L++L + +++H ++ N+L+ A ++S
Sbjct 898 IGKKLNWEARRKIAVGAARGLAFLHHNCIPHIIHRDMKSSNVLIDEQLEA-------RVS 950
Query 759 DPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
D G+ LS ++ PE + +T D + +G LLE+ G+
Sbjct 951 DFGMARLMSVVDTHLSVSTLAGTPGYVPPEYYQ--SFRCTTKGDVYSYGVVLLELL-TGK 1007
Query 813 APLQSRSPSEKEHF-----YQRQHRLPEPSCPQL--------------ATLTSQCLTYEP 853
P S E + + ++ + P+L + CL P
Sbjct 1008 PPTDSADFGEDNNLVGWVKQHTKLKITDVFDPELLKEDPSVELELLEHLKIACACLDDRP 1067
Query 854 TQRPSFRTILRDLTRLQ 870
++RP+ ++ +Q
Sbjct 1068 SRRPTMLKVMAMFKEIQ 1084
>sp|Q9LN59|WAKLK_ARATH Putative wall-associated receptor kinase-like
11 OS=Arabidopsis thaliana OX=3702 GN=WAKL11 PE=3 SV=2
Length=788
Score = 240 bits (612), Expect = 4e-65, Method: Composition-based stats.
Identities = 74/293 (25%), Positives = 121/293 (41%), Gaps = 22/293 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G G V G VAVK K + E+ IL + H H++K
Sbjct 457 LGQGGQGTVYKGML-----VDGRTVAVKKSKV-VDEDKLEEFINEVVILSQINHRHVVKL 510
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA-- 1016
GCC + + LV E++P G+L ++ S L A I ++YLH+
Sbjct 511 LGCCLETEVPT--LVYEFIPNGNLFQHIHEESDDYTKTWGMRLRIAVDIAGALSYLHSAA 568
Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
HRD+ + N+LLD K+ DFG +++V H ++ V + PE
Sbjct 569 SSPIYHRDIKSTNILLDEKYRTKVSDFGTSRSVTIDHTHWTT--VISGTVGYVDPEYYGS 626
Query 1076 YKFYYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
++ SDV+SFGV L EL+T + S + L + M R E+++ R
Sbjct 627 SQYTDKSDVYSFGVVLVELITGEKPVITVSNSQEIRGLADHFRVAMKENRFFEIMDARIR 686
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
+ V +L + C ++ RP + L+ + Q S+ ++
Sbjct 687 DGCKPEQVMAVANLARRCLNSKGKKRPCMRKVFTDLEKI---LASQEDSLVNI 736
Score = 230 bits (586), Expect = 7e-62, Method: Composition-based stats.
Identities = 70/341 (21%), Positives = 121/341 (35%), Gaps = 67/341 (20%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
L +G R + +L ++ LGQG + VY+G L +
Sbjct 423 QQQLNTNKGNVEKTRIFSSRELEK---ATDNFSESRILGQGGQGTVYKGMLVDGRT---- 475
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
V +K D F ++SQ++H H+ + G C
Sbjct 476 ---------------------VAVKKSKVVDEDKLEEFINEVVILSQINHRHVVKLLGCC 514
Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVH 732
+ +V E++ +G L + E W ++ +A +A ALSYL + + H
Sbjct 515 LETEVPTLVYEFIPNGNLFQHIHEESDDYTKTWGMRLRIAVDIAGALSYLHSAASSPIYH 574
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGG 787
++ NILL K+SD G + ++ PE G
Sbjct 575 RDIKSTNILLDEKYRT-------KVSDFGTSRSVTIDHTHWTTVISGTVGYVDPEYY--G 625
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS---------------EKEHFYQRQHR 832
++ + D + FG L+E+ GE P+ + S S E F R
Sbjct 626 SSQYTDKSDVYSFGVVLVELI-TGEKPVITVSNSQEIRGLADHFRVAMKENRFFEIMDAR 684
Query 833 LPEPSCPQ----LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + P+ +A L +CL + +RP R + DL ++
Sbjct 685 IRDGCKPEQVMAVANLARRCLNSKGKKRPCMRKVFTDLEKI 725
>sp|P23437|CDK2_XENLA Cyclin-dependent kinase 2 OS=Xenopus laevis
OX=8355 GN=cdk2 PE=1 SV=3
Length=297
Score = 226 bits (575), Expect = 4e-65, Method: Composition-based stats.
Identities = 72/288 (25%), Positives = 127/288 (44%), Gaps = 28/288 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+
Sbjct 1 MENFQKVEKIGEGTYGVV----YKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICE 1009
L H +I+K E L LV E++ L+ ++ +I LA + + Q+ +
Sbjct 57 ELNHPNIVKLLDVI--HTENKLYLVFEFL-NQDLKKFMDGSNISGISLALVKSYLFQLLQ 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
G+A+ H+ +HRDL +N+L+++D +K+ DFGLA+A R +++ A
Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINSDGAIKLADFGLARAFGVP---VRTFTHEVVTLWYRA 170
Query 1070 PECLKEYK-FYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIA-----QGQ 1118
PE L K + A D+WS G E++T DS + +G G
Sbjct 171 PEILLGCKFYSTAVDIWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDEVSWPGV 230
Query 1119 MTVLRLTELLERGERLPRPDKCPC---EVYHLMKNCWETEASFRPTFE 1163
T+ + R P + L+ + +++ R + +
Sbjct 231 TTMPDYKSTFPKWIRQDFSKVVPPLDEDGRDLLAQMLQYDSNKRISAK 278
Score = 174 bits (441), Expect = 4e-47, Method: Composition-based stats.
Identities = 50/266 (19%), Positives = 95/266 (36%), Gaps = 40/266 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
+ ++ +G+GT VY+ R R G V LK
Sbjct 1 MENFQKVEKIGEGTYGVVYKARNRETGE------------------------IVALKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
LD + SL+ +++H ++ + V + +V E++ + L ++
Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-NQDLKKFMDGSN 95
Query 704 GH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ +A QL L++ + ++H ++ +N+L+ G IKL+D G+
Sbjct 96 ISGISLALVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINSDGA-------IKLADFGL 148
Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + + APE L G STA+D W G E+
Sbjct 149 ARAFGVPVRTFTHEVVTLWYRAPEILLGCKF-YSTAVDIWSLGCIFAEMITRRALFPGDS 207
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ E S P + T+
Sbjct 208 EIDQLFRIFRTLGTPDEVSWPGVTTM 233
>sp|Q8VDG6|M3K21_MOUSE Mitogen-activated protein kinase kinase
kinase 21 OS=Mus musculus OX=10090 GN=Map3k21 PE=1 SV=2
Length=1002
Score = 243 bits (620), Expect = 4e-65, Method: Composition-based stats.
Identities = 88/306 (29%), Positives = 129/306 (42%), Gaps = 54/306 (18%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR---SGWKQEIDILRTLYHEHI 959
+G G FG+V + G+ VAVKA + D ++E + L H +I
Sbjct 116 IGAGGFGQVYRATWQ------GQEVAVKAARRDPEQDAAAAAESVRREARLFAMLRHPNI 169
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-------------IGLAQLLLFAQQ 1006
I+ +G C Q L LV+E+ G+L L + I L+ +A Q
Sbjct 170 IQLRGVCLRQ--PHLCLVLEFARGGALNRALAAAASDPRAPGPRRARRIPPQVLVNWAVQ 227
Query 1007 ICEGMAYLHAQ---HYIHRDLAARNVLLDN--------DRLVKIGDFGLAKAVPEGHEYY 1055
I GM YLH + +HRDL + N+LL ++ +KI DFGLA+ +
Sbjct 228 IARGMLYLHEEAVVPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLAR-----EWHR 282
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
R W APE ++ F SD+WS+GV L+ELLT P + ++ + +A
Sbjct 283 TTRMSAAGTYAWMAPEVIRSSLFSKGSDIWSYGVLLWELLTG-----EVPYRGIDGLAVA 337
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
G LP P CP LMK CWE + RP+F ++ L + E
Sbjct 338 YGVAVN---------KLTLPIPSTCPEPFAKLMKECWEQDPHIRPSFALILQQLTAIEEA 388
Query 1176 YQGQAP 1181
P
Sbjct 389 VLTNMP 394
Score = 211 bits (536), Expect = 1e-54, Method: Composition-based stats.
Identities = 67/338 (20%), Positives = 114/338 (34%), Gaps = 53/338 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
VD + + +G G VY Q V +K
Sbjct 105 VDFERLELKELIGAGGFGQVYRATW--------------------------QGQEVAVKA 138
Query 644 LDPSHHD----IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG------ 693
A + A L + + H ++ + GVC+R P +V E+ G
Sbjct 139 ARRDPEQDAAAAAESVRREARLFAMLRHPNIIQLRGVCLRQPHLCLVLEFARGGALNRAL 198
Query 694 -----PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV---HGNVCGRNILLARL 745
R +P + A Q+A + YL + +V H ++ NILL
Sbjct 199 AAAASDPRAPGPRRARRIPPQVLVNWAVQIARGMLYLHEEAVVPILHRDLKSSNILLLEK 258
Query 746 GLAEGT-SPFIKLSDPGVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+ + +K++D G+ +R W+APE + S D W +G
Sbjct 259 IEHDDICNKTLKITDFGLAREWHRTTRMSAAGTYAWMAPEVIRSSL--FSKGSDIWSYGV 316
Query 803 TLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859
L E+ GE P + + + +P A L +C +P RPSF
Sbjct 317 LLWELL-TGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWEQDPHIRPSF 375
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897
IL+ LT ++ L ++ + S D + ++
Sbjct 376 ALILQQLTAIEEAVLTNMPQESFHSMQEDWKLEIQQMF 413
>sp|Q5JZY3|EPHAA_HUMAN Ephrin type-A receptor 10 OS=Homo sapiens
OX=9606 GN=EPHA10 PE=1 SV=2
Length=1008
Score = 243 bits (621), Expect = 4e-65, Method: Composition-based stats.
Identities = 84/275 (31%), Positives = 125/275 (45%), Gaps = 21/275 (8%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG G FG++ C +VAV L+ R G+ E L H HI++
Sbjct 650 SLGGGRFGELCCGCLQLPGRQE-LLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVR 708
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHY 1019
+G +L +V EY+ G+L +L RH L QL+ + M YL Y
Sbjct 709 LEGVVTRGS--TLMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGY 766
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HR LAAR+VL+ +D + KI FG + + E G SP W APE L+ F
Sbjct 767 VHRGLAARHVLVSSDLVCKISGFG--RGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFS 824
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
ASDVWSFG+ ++E++ + M+ + + +E G RLP P
Sbjct 825 SASDVWSFGIIMWEVMAFGER--------------PYWDMSGQDVIKAVEDGFRLPPPRN 870
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
CP ++ LM +CW+ + RP F + IL + +
Sbjct 871 CPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQ 905
Score = 233 bits (595), Expect = 7e-62, Method: Composition-based stats.
Identities = 92/343 (27%), Positives = 130/343 (38%), Gaps = 49/343 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+D K +T LG G + G L++ G QEL V +
Sbjct 638 KELDAKSVTLERSLGGGRFGELCCGCLQLPGR---------------------QELLVAV 676
Query 642 KVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
+L S D F A + Q H+H+ + GV RG ++VTEY+ HG LD +LR
Sbjct 677 HMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLR 736
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
R G + M + LASA+ YL VH + R++L++ + K+S
Sbjct 737 RHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVS-------SDLVCKIS-- 787
Query 761 GVGLGALSREERVERIP-------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G G G R E V W APE L G S+A D W FG + E+ GE
Sbjct 788 GFGRGPRDRSEAVYTTMSGRSPALWAAPETLQFG--HFSSASDVWSFGIIMWEVMAFGER 845
Query 814 PLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P S + + RLP P +CP L L C +P +RP F I L+++
Sbjct 846 PYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQ 905
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
+ P FG V +
Sbjct 906 DPEPPKCALTTCPRPPTPLADRAFSTFP-------SFGSVGAW 941
>sp|O00506|STK25_HUMAN Serine/threonine-protein kinase 25 OS=Homo
sapiens OX=9606 GN=STK25 PE=1 SV=1
Length=426
Score = 230 bits (587), Expect = 4e-65, Method: Composition-based stats.
Identities = 72/290 (25%), Positives = 124/290 (43%), Gaps = 24/290 (8%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ V + K+ +G+G FG+V Y ++ T E+VA+K + +
Sbjct 1 MAHLRGFANQHSRVDPEELFTKLDRIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEA 56
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL 997
+QEI +L +I +Y G + L ++MEY+ GS D L +
Sbjct 57 EDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTK--LWIIMEYLGGGSALDLLKPGPLEE 114
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ ++I +G+ YLH++ IHRD+ A NVLL VK+ DFG+A + +
Sbjct 115 TYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD---TQIK 171
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
R FW APE +K+ + + +D+WS G+T EL + PP
Sbjct 172 RNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIEL-----AKGEPP----------NS 216
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ +R+ L+ + + ++ C + FRPT + L+
Sbjct 217 DLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLK 266
Score = 201 bits (511), Expect = 5e-55, Method: Composition-based stats.
Identities = 60/297 (20%), Positives = 110/297 (37%), Gaps = 44/297 (15%)
Query 583 RVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
RVD +E T+L +G+G+ VY+G D + V +
Sbjct 13 RVDPEELFTKLDRIGKGSFGEVYKGI------------------------DNHTKEVVAI 48
Query 642 KVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K++D D + +++SQ ++ G ++ + ++ EY+ G L+
Sbjct 49 KIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLK 108
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G + + + +++ L YL ++ +H ++ N+LL+ G +KL+D
Sbjct 109 --PGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGD-------VKLADF 159
Query 761 GVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
GV + R V W+APE + A D W G T +E+ GE P
Sbjct 160 GVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDF--KADIWSLGITAIELA-KGEPPNS 216
Query 817 SRSPSEKEHFYQRQ--HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P + L CL +P RP+ + +L+ +
Sbjct 217 DLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRY 273
>sp|Q7G768|BRL2_ORYSJ Brassinosteroid LRR receptor kinase BRL2
OS=Oryza sativa subsp. japonica OX=39947 GN=BRL2 PE=2 SV=1
Length=1110
Score = 244 bits (623), Expect = 5e-65, Method: Composition-based stats.
Identities = 72/283 (25%), Positives = 120/283 (42%), Gaps = 24/283 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG+V G VA+K L Q + E++ L + H++++
Sbjct 830 IGSGGFGEVFKATLK-----DGSCVAIKKL-IHLSYQGDREFMAEMETLGKIKHKNLVPL 883
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-------IGLAQLLLFAQQICEGMAYLH 1015
G C+ E+ LV E++ GSL D L + Q A+ G+ +LH
Sbjct 884 LGYCKIGEER--LLVYEFMSHGSLEDTLHGDGGRSASPAMSWEQRKKVARGAARGLCFLH 941
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
H IHRD+ + NVLLD D ++ DFG+A+ + + V +P + PE
Sbjct 942 YNCIPHIIHRDMKSSNVLLDGDMEARVADFGMARLISALDTHLSVSTLAGTP-GYVPPEY 1000
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ ++ DV+SFGV L ELLT + L+G + ++ E+L+
Sbjct 1001 YQSFRCTVKGDVYSFGVVLLELLTGRRPTDKDDFGDTNLVGWVKMKVGDGAGKEVLDPEL 1060
Query 1133 RLPRPDKCPCEVYHLM---KNCWETEASFRPTFENLIPILKTV 1172
+ D E+ M C + S RP ++ +L+ +
Sbjct 1061 VVEGAD--ADEMARFMDMALQCVDDFPSKRPNMLQVVAMLREL 1101
Score = 205 bits (522), Expect = 1e-52, Method: Composition-based stats.
Identities = 55/330 (17%), Positives = 110/330 (33%), Gaps = 69/330 (21%)
Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L +L+F ++ + S +G G V++ L+
Sbjct 808 QLRKLTFTQLIEATNGFSTASLIGSGGFGEVFKATLKDGSC------------------- 848
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
V +K L + F + ++ H +L + G C G E ++V E++ H
Sbjct 849 ------VAIKKLIHLSYQGDREFMAEMETLGKIKHKNLVPLLGYCKIGEERLLVYEFMSH 902
Query 693 GPLDVWLRRERGH-----VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744
G L+ L + G + + VA+ A L +L +++H ++ N+LL
Sbjct 903 GSLEDTLHGDGGRSASPAMSWEQRKKVARGAARGLCFLHYNCIPHIIHRDMKSSNVLLD- 961
Query 745 LGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKW 798
+++D G+ LS ++ PE + + D +
Sbjct 962 ------GDMEARVADFGMARLISALDTHLSVSTLAGTPGYVPPEYYQ--SFRCTVKGDVY 1013
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE------------------PSCPQ 840
FG LLE+ G P + + ++ + +
Sbjct 1014 SFGVVLLELL-TGRRPTDKDDFGDTNLVGWVKMKVGDGAGKEVLDPELVVEGADADEMAR 1072
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ QC+ P++RP+ ++ L L
Sbjct 1073 FMDMALQCVDDFPSKRPNMLQVVAMLRELD 1102
>sp|Q9M1Z9|LRK58_ARATH Putative L-type lectin-domain containing
receptor kinase V.8 OS=Arabidopsis thaliana OX=3702 GN=LECRK58
PE=3 SV=1
Length=626
Score = 236 bits (601), Expect = 5e-65, Method: Composition-based stats.
Identities = 88/408 (22%), Positives = 155/408 (38%), Gaps = 25/408 (6%)
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838
L+P L + + GA + + +P+ + P+ S
Sbjct 185 LSPYFLEEMYYGYTASTG--SIGAFHYMLSSYATP--KVENPTWEFIVVPTLPPYPKKSS 240
Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD----VLTVNPDSPASDPTVFHK 894
+ + + CLT I + P A +
Sbjct 241 DRTKKILAVCLTLAVFAVFVASGICFVFYTRHKKVKEVLEEWEIQYGPHRFAYKELLNAT 300
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+ K+ + LG+G FG+V + T G+ +AVK D Q S + EI + L
Sbjct 301 KDFKEKQLLGKGGFGQV----FKGTLPGSNAEIAVKRTSHD-SRQGMSEFLAEISTIGRL 355
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----SIGLAQLLLFAQQICEG 1010
H ++++ G C + ++L LV ++ P GSL YL R+ + Q + +
Sbjct 356 RHPNLVRLLGYCRHK--ENLYLVYDFTPNGSLDKYLDRNENQERLTWEQRFKIIKDVASA 413
Query 1011 MAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ +LH + IHRD+ NVL+D++ +IGDFGLAK +G + R G +
Sbjct 414 LLHLHQEWVQIIIHRDIKPANVLIDHEMNARIGDFGLAKLYDQGLDPQTSRVAG--TFGY 471
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTE 1126
APE L+ + ++DV++FG+ + E++ + P L+ +L +
Sbjct 472 IAPELLRTGRATTSTDVYAFGLVMLEVVCGRRMIERRAPENEEVLVDWILELWESGKLFD 531
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
E R + + L C RP ++ IL V +
Sbjct 532 AAEESIRQEQNRGEIELLLKLGLLCAHHTELIRPNMSAVMQILNGVSQ 579
Score = 211 bits (538), Expect = 1e-56, Method: Composition-based stats.
Identities = 49/261 (19%), Positives = 93/261 (36%), Gaps = 44/261 (17%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
K+ + LG+G V++G L G + +K
Sbjct 299 ATKDFKEKQLLGKGGFGQVFKGTL------------------------PGSNAEIAVKRT 334
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
F S + ++ H +L + G C +V ++ +G LD +L R
Sbjct 335 SHDSRQGMSEFLAEISTIGRLRHPNLVRLLGYCRHKENLYLVYDFTPNGSLDKYLDRNEN 394
Query 705 HVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ W + + + +ASAL +L + ++H ++ N+L+ ++ D
Sbjct 395 QERLTWEQRFKIIKDVASALLHLHQEWVQIIIHRDIKPANVLIDHE-------MNARIGD 447
Query 760 PGVGLGA-----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ ++APE L G +T+ D + FG +LE+ G
Sbjct 448 FGLAKLYDQGLDPQTSRVAGTFGYIAPELLRTGRA--TTSTDVYAFGLVMLEVVC-GRRM 504
Query 815 LQSRSPSEKEHFYQRQHRLPE 835
++ R+P +E L E
Sbjct 505 IERRAPENEEVLVDWILELWE 525
>sp|Q00655|KSYK_PIG Tyrosine-protein kinase SYK OS=Sus scrofa
OX=9823 GN=SYK PE=1 SV=1
Length=628
Score = 236 bits (601), Expect = 5e-65, Method: Composition-based stats.
Identities = 99/325 (30%), Positives = 144/325 (44%), Gaps = 23/325 (7%)
Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY--LKKIRDLGEGHF 908
YE + P L V+ R + ++LG G+F
Sbjct 316 YESDRGPWANEREAQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNF 375
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
G V Y V + LK + P + E ++++ L + +I++ G CE
Sbjct 376 GTVKKGYYQMKKVVKTVAVKI--LKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICE 433
Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
+S LVME LG L YL ++ + ++ Q+ GM YL +++HRDLAA
Sbjct 434 ---AESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEECNFVHRDLAA 490
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
RNVLL KI DFGL+KA+ YY+ + G PV WYAPEC+ YKF SDVWS
Sbjct 491 RNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWS 550
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
FGV ++E ++ M ++ +LE+GER+ P CP E+Y
Sbjct 551 FGVLMWEAFSYGQK--------------PYRGMKGSEVSAMLEKGERMGCPPGCPREMYE 596
Query 1147 LMKNCWETEASFRPTFENLIPILKT 1171
LM CW + RP F + L+
Sbjct 597 LMTLCWTYDVENRPGFVAVELRLRN 621
Score = 206 bits (525), Expect = 5e-55, Method: Composition-based stats.
Identities = 66/290 (23%), Positives = 114/290 (39%), Gaps = 40/290 (14%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ LG G V +G +++ K+ + P LK
Sbjct 366 EDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDP----------ALK-------- 407
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
A++M Q+ + ++ + G+C ++V E E GPL+ +L++ R HV
Sbjct 408 --DELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNR-HVKDKN 463
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+ + Q++ + YLE N VH ++ RN+LL T + K+SD G+ + E
Sbjct 464 IIELVHQVSMGMKYLEECNFVHRDLAARNVLL-------VTQHYAKISDFGLSKALRADE 516
Query 771 ERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ + W APEC+ S+ D W FG + E G+ P + SE
Sbjct 517 NYYKAQTHGKWPVKWYAPECI--NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEV 574
Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
++ R+ P ++ L + C TY+ RP F + L
Sbjct 575 SAMLEKGERMGCPPGCPREMYELMTLCWTYDVENRPGFVAVELRLRNYYY 624
>sp|Q9S9M2|WAKLD_ARATH Wall-associated receptor kinase-like 4
OS=Arabidopsis thaliana OX=3702 GN=WAKL4 PE=2 SV=2
Length=761
Score = 239 bits (609), Expect = 5e-65, Method: Composition-based stats.
Identities = 74/287 (26%), Positives = 114/287 (40%), Gaps = 18/287 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R LG+G G V G +VAVK KA + E+ +L +
Sbjct 422 DNFNTNRVLGQGGQGTVYKGML-----VDGRIVAVKRSKA-MDEDKVEEFINEVVVLAQI 475
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEG 1010
H +I+K GCC + + LV E+VP G L L + L A +I
Sbjct 476 NHRNIVKLLGCCLET--EVPVLVYEFVPNGDLCKRLRDECDDYIMTWEVRLHIAIEIAGA 533
Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
++YLH+ HRD+ N+LLD VK+ DFG +++V + + G +
Sbjct 534 LSYLHSAASFPIYHRDIKTTNILLDEKYQVKVSDFGTSRSVTIDQTHLTTQVAG--TFGY 591
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHC-DSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
PE + KF SDV+SFGV L EL+T SS+ + + R +
Sbjct 592 VDPEYFQSSKFTDKSDVYSFGVVLVELITGKNPSSRVQSEENRGFAAHFVAAVKENRFLD 651
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+++ + V L K C + RP + L+ +
Sbjct 652 IVDERIKDECNLDQVMAVAKLAKRCLNRKGKKRPNMREVSVELERIR 698
Score = 219 bits (557), Expect = 3e-58, Method: Composition-based stats.
Identities = 65/340 (19%), Positives = 117/340 (34%), Gaps = 63/340 (19%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
LGQG + VY+G L V +K
Sbjct 420 ATDNFNTNRVLGQGGQGTVYKGMLVDGRI-------------------------VAVKRS 454
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D F +++Q++H ++ + G C+ ++V E+V +G L LR E
Sbjct 455 KAMDEDKVEEFINEVVVLAQINHRNIVKLLGCCLETEVPVLVYEFVPNGDLCKRLRDECD 514
Query 705 HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
M W ++ +A ++A ALSYL + + H ++ NILL +K+SD
Sbjct 515 DYIMTWEVRLHIAIEIAGALSYLHSAASFPIYHRDIKTTNILLDEKYQ-------VKVSD 567
Query 760 PGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G + ++ PE ++ + D + FG L+E+ G+ P
Sbjct 568 FGTSRSVTIDQTHLTTQVAGTFGYVDPEYFQ--SSKFTDKSDVYSFGVVLVELI-TGKNP 624
Query 815 LQSRSPSEKEHFYQR--------------QHRLPEPSC----PQLATLTSQCLTYEPTQR 856
E F R+ + +A L +CL + +R
Sbjct 625 SSRVQSEENRGFAAHFVAAVKENRFLDIVDERIKDECNLDQVMAVAKLAKRCLNRKGKKR 684
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896
P+ R + +L R++ + + + D D +
Sbjct 685 PNMREVSVELERIRSSSYKSEIHNDDDDDDDDDDEDDQAM 724
>sp|Q54R58|YTYK2_DICDI Probable tyrosine-protein kinase DDB_G0283397
OS=Dictyostelium discoideum OX=44689 GN=DDB_G0283397
PE=3 SV=1
Length=918
Score = 241 bits (616), Expect = 6e-65, Method: Composition-based stats.
Identities = 83/284 (29%), Positives = 123/284 (43%), Gaps = 37/284 (13%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK--ADCGPQHRSGWKQEIDILRTLYHEHI 959
++G+G FGKV + G+ VA+K + + +E+ I+ L H
Sbjct 182 EIGQGFFGKVYKARWR------GKSVALKKITLIKFRDLTETEIFDKEVSIMSKLCHPTC 235
Query 960 IKYKGCCE-DQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLH 1015
+ + G C D ++MEY+ GSLR L S + + L A+ I EGM YLH
Sbjct 236 VMFIGACSLDGPSNDRSIIMEYMEGGSLRRLLDEKSSYHLPPSLQLSIARDIAEGMNYLH 295
Query 1016 AQ----HYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
+HRDL + N+LL++ V KI DFGL+K + G + W AP
Sbjct 296 TNFKEGPIVHRDLTSSNILLNSSYTVAKINDFGLSKEMKPGPTE---MTAAMGSLAWMAP 352
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE- 1129
EC K + DV+SF + L+E++T D M LRL L
Sbjct 353 ECFKAENYTEKVDVYSFAIILWEIVTCRDP---------------YNGMEPLRLAFLASV 397
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
RLP + P L+ CW S RP+F+ ++ IL +
Sbjct 398 EDYRLPL-NGFPPYWVELISKCWNITPSLRPSFKEILQILNQIE 440
Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats.
Identities = 73/308 (24%), Positives = 122/308 (40%), Gaps = 46/308 (15%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S L H + +E+T +GQG VY+ R R G+ +
Sbjct 165 STLKKHEIPSRELTVEKEIGQGFFGKVYKARWR--------------------GKSVALK 204
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE---NIMVTEYVEHG 693
++K D + +I F + S+MS++ H G C ++ EY+E G
Sbjct 205 KITLIKFRDLTETEI---FDKEVSIMSKLCHPTCVMFIGACSLDGPSNDRSIIMEYMEGG 261
Query 694 PLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENK----NLVHGNVCGRNILLARLGLA 748
L L + H+P + ++ +A+ +A ++YL +VH ++ NILL
Sbjct 262 SLRRLLDEKSSYHLPPSLQLSIARDIAEGMNYLHTNFKEGPIVHRDLTSSNILLNSSYT- 320
Query 749 EGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
K++D G+ G + + W+APEC A + + +D + F L
Sbjct 321 -----VAKINDFGLSKEMKPGPTEMTAAMGSLAWMAPECFK--AENYTEKVDVYSFAIIL 373
Query 805 LEICFDGEAPLQSRSPSEKEHF-YQRQHRLP-EPSCPQLATLTSQCLTYEPTQRPSFRTI 862
EI P P +RLP P L S+C P+ RPSF+ I
Sbjct 374 WEIVTC-RDPYNGMEPLRLAFLASVEDYRLPLNGFPPYWVELISKCWNITPSLRPSFKEI 432
Query 863 LRDLTRLQ 870
L+ L +++
Sbjct 433 LQILNQIE 440
>sp|C0LGN2|Y3148_ARATH Probable leucine-rich repeat receptor-like
serine/threonine-protein kinase At3g14840 OS=Arabidopsis
thaliana OX=3702 GN=LRR-RLK PE=1 SV=1
Length=1020
Score = 243 bits (619), Expect = 6e-65, Method: Composition-based stats.
Identities = 77/310 (25%), Positives = 117/310 (38%), Gaps = 19/310 (6%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
Q L S + +GEG FG V G ++AV
Sbjct 645 QMEKDFKNLDFQISSFSLRQIKVATDNFDPANKIGEGGFGPVHKGI-----MTDGTVIAV 699
Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
K L A Q + EI ++ L H H++K GCC + + L LV EY+ SL
Sbjct 700 KQLSAK-SKQGNREFLNEIAMISALQHPHLVKLYGCCVEGDQ--LLLVYEYLENNSLARA 756
Query 990 L-----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGD 1041
L + + I G+AYLH + +HRD+ A NVLLD + KI D
Sbjct 757 LFGPQETQIPLNWPMRQKICVGIARGLAYLHEESRLKIVHRDIKATNVLLDKELNPKISD 816
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLAK E + + R G + APE +DV+SFGV E++ ++
Sbjct 817 FGLAKLDEEENTHISTRVAG--TYGYMAPEYAMRGHLTDKADVYSFGVVALEIVHGKSNT 874
Query 1102 QSP-PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
S L+ L E+++ + + + C RP
Sbjct 875 SSRSKADTFYLLDWVHVLREQNTLLEVVDPRLGTDYNKQEALMMIQIGMLCTSPAPGDRP 934
Query 1161 TFENLIPILK 1170
+ ++ +L+
Sbjct 935 SMSTVVSMLE 944
Score = 230 bits (587), Expect = 8e-61, Method: Composition-based stats.
Identities = 60/314 (19%), Positives = 112/314 (36%), Gaps = 52/314 (17%)
Query 536 CLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHL 595
L+ R C P+ + + ++ L +V + +
Sbjct 625 FLVLLIGGILWWRGCLRPKSQMEKDF------KNLDFQISSFSLRQIKVATDNFDPANKI 678
Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655
G+G V++G + + +K L F
Sbjct 679 GEGGFGPVHKGIMTDG-------------------------TVIAVKQLSAKSKQGNREF 713
Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KM 712
+++S + H HL ++G CV G + ++V EY+E+ L L + +P+ W +
Sbjct 714 LNEIAMISALQHPHLVKLYGCCVEGDQLLLVYEYLENNSLARALFGPQETQIPLNWPMRQ 773
Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769
+ +A L+YL + +VH ++ N+LL + K+SD G+
Sbjct 774 KICVGIARGLAYLHEESRLKIVHRDIKATNVLLDKELNP-------KISDFGLAKLDEEE 826
Query 770 EERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ ++APE G L+ D + FG LEI G++ SRS ++
Sbjct 827 NTHISTRVAGTYGYMAPEYAMRG--HLTDKADVYSFGVVALEIV-HGKSNTSSRSKADTF 883
Query 825 HFYQRQHRLPEPSC 838
+ H L E +
Sbjct 884 YLLDWVHVLREQNT 897
>sp|Q9SKG5|SERK4_ARATH Somatic embryogenesis receptor kinase 4
OS=Arabidopsis thaliana OX=3702 GN=SERK4 PE=1 SV=2
Length=620
Score = 235 bits (600), Expect = 7e-65, Method: Composition-based stats.
Identities = 71/325 (22%), Positives = 123/325 (38%), Gaps = 20/325 (6%)
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916
R + +V + LG G FGKV
Sbjct 254 WLRRKPQDHFFDVPAEEDPEVHLGQLKRFTLRELLVATDNFSNKNVLGRGGFGKVYKGRL 313
Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976
G +VAVK LK + ++ E++++ H ++++ +G C E+ L
Sbjct 314 -----ADGNLVAVKRLKEERTKGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTER--LL 366
Query 977 VMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028
V Y+ GS+ L + + A G+AYLH IHRD+ A N
Sbjct 367 VYPYMANGSVASCLRERPEGNPALDWPKRKHIALGSARGLAYLHDHCDQKIIHRDVKAAN 426
Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
+LLD + +GDFGLAK + + V + APE L K +DV+ +G
Sbjct 427 ILLDEEFEAVVGDFGLAKLMNYNDSH--VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 484
Query 1089 VTLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
V L EL+T + + + L+ + + +L L++ + ++
Sbjct 485 VMLLELITGQKAFDLARLANDDDIMLLDWVKEVLKEKKLESLVDAELEGKYVETEVEQLI 544
Query 1146 HLMKNCWETEASFRPTFENLIPILK 1170
+ C ++ A RP ++ +L+
Sbjct 545 QMALLCTQSSAMERPKMSEVVRMLE 569
Score = 194 bits (492), Expect = 8e-51, Method: Composition-based stats.
Identities = 68/341 (20%), Positives = 122/341 (36%), Gaps = 50/341 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V + + LG+G VY+GRL V +K
Sbjct 289 VATDNFSNKNVLGRGGFGKVYKGRLADGN-------------------------LVAVKR 323
Query 644 LDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-R 701
L L F ++S H +L + G C+ E ++V Y+ +G + LR R
Sbjct 324 LKEERTKGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMANGSVASCLRER 383
Query 702 ERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
G+ + W + +A A L+YL ++ ++H +V NILL A
Sbjct 384 PEGNPALDWPKRKHIALGSARGLAYLHDHCDQKIIHRDVKAANILLDEEFEAV------- 436
Query 757 LSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
+ D G+ + V I +APE L G + S D +G+G LLE+
Sbjct 437 VGDFGLAKLMNYNDSHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGYGVMLLELITGQ 494
Query 812 EAPLQSR--SPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFRTILRDLT 867
+A +R + + + L E L A L + + E Q + +
Sbjct 495 KAFDLARLANDDDIMLLDWVKEVLKEKKLESLVDAELEGKYVETEVEQLIQMALLCTQSS 554
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
++ +++V+ + ++ ++ I D +
Sbjct 555 AMERPKMSEVVRMLEGDGLAERWEEWQKEEMPIHDFNYQAY 595
>sp|Q5E9L6|STK4_BOVIN Serine/threonine-protein kinase 4 OS=Bos
taurus OX=9913 GN=STK4 PE=2 SV=1
Length=487
Score = 231 bits (590), Expect = 7e-65, Method: Composition-based stats.
Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K
Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+K C R T L+
Sbjct 250 WSDSFMDFVKQCLVKSPEQRATATQLLQ 277
Score = 202 bits (515), Expect = 6e-55, Method: Composition-based stats.
Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L + S + ++ L LG+G+ +VY+ + G
Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K + + S+M Q H+ +G + + +V EY G +
Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + Q L YL +H ++ NILL G
Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163
Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D GV R + W+APE + + D W G T +E+ +G
Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220
Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P P R PE QCL P QR + +L+
Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDSFMDFVKQCLVKSPEQRATATQLLQHPF 280
>sp|O18735|ERBB2_CANLF Receptor tyrosine-protein kinase erbB-2
OS=Canis lupus familiaris OX=9615 GN=ERBB2 PE=2 SV=1
Length=1259
Score = 244 bits (624), Expect = 7e-65, Method: Composition-based stats.
Identities = 87/272 (32%), Positives = 133/272 (49%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + VA+K L+ + P+ E ++ + ++ +
Sbjct 725 LGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRL 784
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C +QLV + +P G L D++ H +G LL + QI +GM+YL +
Sbjct 785 LGICLTST---VQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLV 841
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W A E + +F +
Sbjct 842 HRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWMALESIPPRRFTH 900
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + + +LLE+GERLP+P C
Sbjct 901 QSDVWSYGVTVWELMTFG--------------AKPYDGIPAREIPDLLEKGERLPQPPIC 946
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW ++ RP F L+ +
Sbjct 947 TIDVYMIMVKCWMIDSECRPRFRELVAEFSRM 978
Score = 221 bits (562), Expect = 3e-57, Method: Composition-based stats.
Identities = 64/316 (20%), Positives = 123/316 (39%), Gaps = 39/316 (12%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+P +Q + + E+ ++ LG G VY+G +G
Sbjct 700 TPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENV-------------- 745
Query 630 GRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ V +KVL + + A +M+ V +++ + G+C+ +VT+
Sbjct 746 ------KIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQ 798
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+ +G L +R RG + + Q+A +SYLE+ LVH ++ RN+L+
Sbjct 799 LMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPN-- 856
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+K++D G+ + I W+A E +P + D W +G
Sbjct 857 -----HVKITDFGLARLLDIDETEYHADGGKVPIKWMALESIP--PRRFTHQSDVWSYGV 909
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860
T+ E+ G P E ++ RLP+P + + +C + RP FR
Sbjct 910 TVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFR 969
Query 861 TILRDLTRLQPHNLAD 876
++ + +R+
Sbjct 970 ELVAEFSRMARDPQRF 985
>sp|O80623|Y2393_ARATH Probable receptor-like protein kinase At2g39360
OS=Arabidopsis thaliana OX=3702 GN=At2g39360 PE=1 SV=1
Length=815
Score = 239 bits (611), Expect = 7e-65, Method: Composition-based stats.
Identities = 71/280 (25%), Positives = 125/280 (45%), Gaps = 17/280 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FGKV VAVK A Q + +K E+++L H H++
Sbjct 493 IGVGGFGKVYKGVLR-----DKTEVAVKR-GAPQSRQGLAEFKTEVEMLTQFRHRHLVSL 546
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA-- 1016
G C++ E + +V EY+ G+L+D+L + + Q L G+ YLH
Sbjct 547 IGYCDENSE--MIIVYEYMEKGTLKDHLYDLDDKPRLSWRQRLEICVGAARGLHYLHTGS 604
Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ IHRD+ + N+LLD++ + K+ DFGL+K P+ + + V + PE L
Sbjct 605 TRAIIHRDVKSANILLDDNFMAKVADFGLSKTGPDLDQTH-VSTAVKGSFGYLDPEYLTR 663
Query 1076 YKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ SDV+SFGV + E++ S P + + LI A + +L ++++
Sbjct 664 QQLTEKSDVYSFGVVMLEVVCGRPVIDPSLPREKVNLIEWAMKLVKKGKLEDIIDPFLVG 723
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ + + + C RP +L+ L+ + +
Sbjct 724 KVKLEEVKKYCEVTEKCLSQNGIERPAMGDLLWNLEFMLQ 763
Score = 227 bits (579), Expect = 9e-61, Method: Composition-based stats.
Identities = 64/321 (20%), Positives = 113/321 (35%), Gaps = 64/321 (20%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
L+ + + + +G G VY+G LR +
Sbjct 476 PLALIKEATDDFDESLVIGVGGFGKVYKGVLRD-------------------------KT 510
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
V +K P F +++Q H HL + G C E I+V EY+E G L
Sbjct 511 EVAVKRGAPQSRQGLAEFKTEVEMLTQFRHRHLVSLIGYCDENSEMIIVYEYMEKGTLKD 570
Query 698 WLR--RERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTS 752
L ++ + ++ + A L YL + ++H +V NILL +
Sbjct 571 HLYDLDDKPRLSWRQRLEICVGAARGLHYLHTGSTRAIIHRDVKSANILLD-------DN 623
Query 753 PFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
K++D G+ ++ +L PE L L+ D + FG +LE
Sbjct 624 FMAKVADFGLSKTGPDLDQTHVSTAVKGSFGYLDPEYLT--RQQLTEKSDVYSFGVVMLE 681
Query 807 ICFDGEAPLQSRSPSEKEHFYQR------QHRLPEPSCPQL------------ATLTSQC 848
+ G + P EK + + + +L + P L +T +C
Sbjct 682 VVC-GRPVIDPSLPREKVNLIEWAMKLVKKGKLEDIIDPFLVGKVKLEEVKKYCEVTEKC 740
Query 849 LTYEPTQRPSFRTILRDLTRL 869
L+ +RP+ +L +L +
Sbjct 741 LSQNGIERPAMGDLLWNLEFM 761
>sp|P27966|RMIL_AVEVR Serine/threonine-protein kinase-transforming
protein Rmil OS=Avian rous-associated virus type 1 OX=11950
GN=V-RMIL PE=3 SV=1
Length=450
Score = 230 bits (587), Expect = 7e-65, Method: Composition-based stats.
Identities = 76/306 (25%), Positives = 130/306 (42%), Gaps = 31/306 (10%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+ + +SD + + +G G FG V + VAVK L
Sbjct 61 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-------DVAVKMLNV 113
Query 935 DC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991
PQ +K E+ +LR H +I+ + G + L +V ++ SL +L
Sbjct 114 TAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY---STKPQLAIVTQWCEGSSLYHHLHII 170
Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
+ +L+ A+Q +GM YLHA+ IHRDL + N+ L D VKIGDFGLA
Sbjct 171 ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRW 230
Query 1052 HEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQ--SPPT 1106
++ E + W APE ++ + + + SDV++FG+ LYEL+T +
Sbjct 231 SGSHQF-EQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRD 289
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ + ++G + ++ CP + LM C + + RP F ++
Sbjct 290 QIIFMVGRGYLSPDLSKVR------------SNCPKAMKRLMAECLKKKRDERPLFPQIL 337
Query 1167 PILKTV 1172
++ +
Sbjct 338 ASIELL 343
Score = 223 bits (569), Expect = 2e-62, Method: Composition-based stats.
Identities = 71/379 (19%), Positives = 130/379 (34%), Gaps = 57/379 (15%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSF-HRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
P P R +TL S + +IT +G G+ VY+G+ +
Sbjct 46 PGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD 105
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSHTH 669
V +K+L+ + AF ++ + H +
Sbjct 106 ---------------------------VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVN 138
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729
+ G + P+ +VT++ E L L M + +A+Q A + YL K+
Sbjct 139 ILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKS 197
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPEC 783
++H ++ NI L +K+ D G+ G+ E+ I W+APE
Sbjct 198 IIHRDLKSNNIFLHE-------DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEV 250
Query 784 LPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP------ 836
+ N S D + FG L E+ G+ P + + ++ F + L
Sbjct 251 IRMQDKNPYSFQSDVYAFGIVLYELM-TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRS 309
Query 837 SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL----TRLQPHNLADVLTVNPDSPASDPTV 891
+CP+ + L ++CL + +RP F IL + L + + +
Sbjct 310 NCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDF 369
Query 892 FHKRYLKKIRDLGEGHFGK 910
+ G G+
Sbjct 370 SLYACASPKTPIQAGGIGE 388
>sp|Q39202|RLK1_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase RLK1 OS=Arabidopsis thaliana OX=3702 GN=RLK1
PE=2 SV=2
Length=832
Score = 240 bits (612), Expect = 8e-65, Method: Composition-based stats.
Identities = 74/289 (26%), Positives = 122/289 (42%), Gaps = 12/289 (4%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+LG G FG V Y G+ VAVK L + +K E+ ++ ++H+++++
Sbjct 536 ELGRGAFGIVYKG-YLEVAGGSEVTVAVKKLDR-LDLDNEKEFKNEVKVIGQIHHKNLVR 593
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLH---AQ 1017
G C + + +V E++P G+L ++L R A I G+ YLH ++
Sbjct 594 LIGFCNEGQSQ--MIVYEFLPQGTLANFLFRRPRPSWEDRKNIAVAIARGILYLHEECSE 651
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IH D+ +N+LLD +I DFGLAK + Y + + APE +
Sbjct 652 QIIHCDIKPQNILLDEYYTPRISDFGLAKLLLMNQTY--TLTNIRGTKGYVAPEWFRNSP 709
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
DV+S+GV L E++ C + LI A RL +L E
Sbjct 710 ITSKVDVYSYGVMLLEIV--CCKKAVDLEDNVILINWAYDCFRQGRLEDLTEDDSEAMND 767
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
+ + C + E RP N+ +L+ V + + PS +S
Sbjct 768 METVERYVKIAIWCIQEEHGMRPNMRNVTQMLEGVIQVFDPPNPSPYST 816
Score = 226 bits (575), Expect = 4e-60, Method: Composition-based stats.
Identities = 80/432 (19%), Positives = 150/432 (35%), Gaps = 67/432 (16%)
Query 482 RLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAG 541
+ L+ +RS D +++R I G + L A L +
Sbjct 424 KFPLSHGERSPRGDSDTFIKVRNRSIADVP------VTGNRAKKLDWLIIACSVLLGTSA 477
Query 542 DDCFSLRRCCLPQPGETSNLIIMRG-------ARASPRTLNLSQLSFHRVDQKEITQLSH 594
F C + ++ N++ + A + LNL ++ + +
Sbjct 478 FVIFD-TSCSYRKTKKSKNMMKNQARDIGRTTATTTANELNLRVFTYGELAEATRDFTEE 536
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LG+G VY+G L V G G E+ V +K LD D
Sbjct 537 LGRGAFGIVYKGYLEVAG---------------------GSEVTVAVKKLDRLDLDNEKE 575
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
F ++ Q+ H +L + G C G ++V E++ G L +L R R + +
Sbjct 576 FKNEVKVIGQIHHKNLVRLIGFCNEGQSQMIVYEFLPQGTLANFLFR-RPRPSWEDRKNI 634
Query 715 AQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771
A +A + YL ++ ++H ++ +NILL ++SD G+ L +
Sbjct 635 AVAIARGILYLHEECSEQIIHCDIKPQNILLDEYYTP-------RISDFGLAKLLLMNQT 687
Query 772 RV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP--SEKE 824
++APE + +++ +D + +G LLEI +A +
Sbjct 688 YTLTNIRGTKGYVAPEWFRN--SPITSKVDVYSYGVMLLEIVCCKKAVDLEDNVILINWA 745
Query 825 HFYQRQHRLPE------------PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
+ RQ RL + + + + C+ E RP+ R + + L +
Sbjct 746 YDCFRQGRLEDLTEDDSEAMNDMETVERYVKIAIWCIQEEHGMRPNMRNVTQMLEGVIQV 805
Query 873 NLADVLTVNPDS 884
+
Sbjct 806 FDPPNPSPYSTF 817
>sp|P43298|TMK1_ARATH Receptor protein kinase TMK1 OS=Arabidopsis
thaliana OX=3702 GN=TMK1 PE=1 SV=1
Length=942
Score = 241 bits (616), Expect = 8e-65, Method: Composition-based stats.
Identities = 82/291 (28%), Positives = 124/291 (43%), Gaps = 23/291 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961
LG G FG V G +AVK ++ + + +K EI +L + H H++
Sbjct 594 LGSGGFGVVYKGEL-----HDGTKIAVKRMENGVIAGKGFAEFKSEIAVLTKVRHRHLVT 648
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR------HSIGLAQLLLFAQQICEGMAYLH 1015
G C D EK LV EY+P G+L +L + Q L A + G+ YLH
Sbjct 649 LLGYCLDGNEK--LLVYEYMPQGTLSRHLFEWSEEGLKPLLWKQRLTLALDVARGVEYLH 706
Query 1016 ---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Q +IHRDL N+LL +D K+ DFGL + PEG R G + APE
Sbjct 707 GLAHQSFIHRDLKPSNILLGDDMRAKVADFGLVRLAPEGKGSIETRIAG--TFGYLAPEY 764
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ DV+SFGV L EL+T S +S P + + L+ + +
Sbjct 765 AVTGRVTTKVDVYSFGVILMELITGRKSLDESQPEESIHLVSWFKRMYINKEASFKKAID 824
Query 1132 ERLPRPDKCPCEVY---HLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+ ++ V+ L +C E RP + + IL ++ E ++
Sbjct 825 TTIDLDEETLASVHTVAELAGHCCAREPYQRPDMGHAVNILSSLVELWKPS 875
Score = 216 bits (550), Expect = 2e-56, Method: Composition-based stats.
Identities = 66/309 (21%), Positives = 110/309 (36%), Gaps = 70/309 (23%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ + LG G VY+G L ++ +K ++
Sbjct 585 TNNFSSDNILGSGGFGVVYKGELHDG-------------------------TKIAVKRME 619
Query 646 PS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--R 701
F +++++V H HL + G C+ G E ++V EY+ G L L
Sbjct 620 NGVIAGKGFAEFKSEIAVLTKVRHRHLVTLLGYCLDGNEKLLVYEYMPQGTLSRHLFEWS 679
Query 702 ERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
E G P+ W ++ +A +A + YL +++ +H ++ NILL G K
Sbjct 680 EEGLKPLLWKQRLTLALDVARGVEYLHGLAHQSFIHRDLKPSNILL-------GDDMRAK 732
Query 757 LSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ A + + +LAPE G ++T +D + FG L+E+ G
Sbjct 733 VADFGLVRLAPEGKGSIETRIAGTFGYLAPEYAVTG--RVTTKVDVYSFGVILMELI-TG 789
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS---------------------CPQLATLTSQCLT 850
L P E H R+ +A L C
Sbjct 790 RKSLDESQPEESIHLVSWFKRMYINKEASFKKAIDTTIDLDEETLASVHTVAELAGHCCA 849
Query 851 YEPTQRPSF 859
EP QRP
Sbjct 850 REPYQRPDM 858
>sp|C0LGG6|Y5189_ARATH Probable LRR receptor-like protein kinase
At1g51890 OS=Arabidopsis thaliana OX=3702 GN=At1g51890 PE=1
SV=2
Length=876
Score = 240 bits (613), Expect = 8e-65, Method: Composition-based stats.
Identities = 72/291 (25%), Positives = 124/291 (43%), Gaps = 23/291 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V D T VAVK L Q +K E+++L ++H H++
Sbjct 576 LGKGGFGTVYHGNLDDT------QVAVKMLSH-SSAQGYKEFKAEVELLLRVHHRHLVGL 628
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGMAYLHA-- 1016
G C+D +L L+ EY+ G LR+ + + + + A + +G+ YLH
Sbjct 629 VGYCDDGD--NLALIYEYMEKGDLRENMSGKHSVNVLSWETRMQIAVEAAQGLEYLHNGC 686
Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRD+ N+LL+ K+ DFGL+++ P E + + +P + PE +
Sbjct 687 RPPMVHRDVKPTNILLNERSQAKLADFGLSRSFPVDGESHVMTVVAGTP-GYLDPEYYRT 745
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
SDV+SFGV L E++T+ + + + +T + +++
Sbjct 746 NWLSEKSDVYSFGVVLLEIVTN-QPVMNKNRERPHINEWVMFMLTNGDIKSIVDPKLNED 804
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK-----TVHEKYQGQAP 1181
+V L C +S RPT +++ L + K QA
Sbjct 805 YDTNGVWKVVELALACVNPSSSRRPTMPHVVMELNECLALEIERKQGSQAT 855
Score = 209 bits (533), Expect = 1e-54, Method: Composition-based stats.
Identities = 71/319 (22%), Positives = 113/319 (35%), Gaps = 61/319 (19%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+ ++ V + LG+G VY G L +
Sbjct 558 RKFTYSEVLKMTKNFERVLGKGGFGTVYHGNL--------------------------DD 591
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+V +K+L S F L+ +V H HL + G C G ++ EY+E G L
Sbjct 592 TQVAVKMLSHSSAQGYKEFKAEVELLLRVHHRHLVGLVGYCDDGDNLALIYEYMEKGDLR 651
Query 697 VWLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT 751
+ + ++W +M +A + A L YL N +VH +V NILL A
Sbjct 652 ENMSGKHSVNVLSWETRMQIAVEAAQGLEYLHNGCRPPMVHRDVKPTNILLNERSQA--- 708
Query 752 SPFIKLSDPGVGLG-ALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
KL+D G+ + E V +L PE N LS D + FG LL
Sbjct 709 ----KLADFGLSRSFPVDGESHVMTVVAGTPGYLDPEYYRT--NWLSEKSDVYSFGVVLL 762
Query 806 EICFDGEAPLQSR---SPSEKEHFYQRQHRLPEPSCPQL------------ATLTSQCLT 850
EI + ++R +E F + P+L L C+
Sbjct 763 EIVTNQPVMNKNRERPHINEWVMFMLTNGDIKSIVDPKLNEDYDTNGVWKVVELALACVN 822
Query 851 YEPTQRPSFRTILRDLTRL 869
++RP+ ++ +L
Sbjct 823 PSSSRRPTMPHVVMELNEC 841
>sp|Q9S9M5|WAKLA_ARATH Wall-associated receptor kinase-like 1
OS=Arabidopsis thaliana OX=3702 GN=WAKL1 PE=2 SV=1
Length=730
Score = 238 bits (606), Expect = 8e-65, Method: Composition-based stats.
Identities = 72/292 (25%), Positives = 117/292 (40%), Gaps = 23/292 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G G V G +VAVK K + EI +L + H +I+K
Sbjct 435 LGQGGQGTVYKGML-----VDGSIVAVKRSKV-VDEDKMEEFINEIVLLSQINHRNIVKL 488
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQ- 1017
GCC + E + LV EY+P G L L S + L A +I + Y+H+
Sbjct 489 LGCCLE-TEVPI-LVYEYIPNGDLFKRLHDESDDYTMTWEVRLRIAIEIAGALTYMHSAA 546
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
HRD+ N+LLD K+ DFG +++V + + + PE
Sbjct 547 SFPIFHRDIKTTNILLDEKYRAKVSDFGTSRSVTLDQTH--LTTLVAGTFGYMDPEYFLS 604
Query 1076 YKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
++ + SDV+SFGV L EL+T S+ + L M R+ ++++ +
Sbjct 605 SQYTHKSDVYSFGVVLVELITGEKPLSRVRSEEGRGLATHFLEAMKENRVIDIIDIRIKD 664
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
+ V L + C + RP + + L+ + +P V
Sbjct 665 ESKLEQVMAVAKLARKCLNRKGKNRPNMKEVSNELERIR-----SSPEDLDV 711
Score = 225 bits (573), Expect = 2e-60, Method: Composition-based stats.
Identities = 64/314 (20%), Positives = 113/314 (36%), Gaps = 63/314 (20%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ LGQG + VY+G L V +K
Sbjct 425 ATDNFSIDRVLGQGGQGTVYKGMLVDGSI-------------------------VAVKRS 459
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D F L+SQ++H ++ + G C+ I+V EY+ +G L L E
Sbjct 460 KVVDEDKMEEFINEIVLLSQINHRNIVKLLGCCLETEVPILVYEYIPNGDLFKRLHDESD 519
Query 705 HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
M W ++ +A ++A AL+Y+ + + H ++ NILL A K+SD
Sbjct 520 DYTMTWEVRLRIAIEIAGALTYMHSAASFPIFHRDIKTTNILLDEKYRA-------KVSD 572
Query 760 PGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G + ++ PE ++ + D + FG L+E+ GE P
Sbjct 573 FGTSRSVTLDQTHLTTLVAGTFGYMDPEYFL--SSQYTHKSDVYSFGVVLVELI-TGEKP 629
Query 815 LQSRSPSEKEHF------YQRQHRLPEP------------SCPQLATLTSQCLTYEPTQR 856
L E +++R+ + +A L +CL + R
Sbjct 630 LSRVRSEEGRGLATHFLEAMKENRVIDIIDIRIKDESKLEQVMAVAKLARKCLNRKGKNR 689
Query 857 PSFRTILRDLTRLQ 870
P+ + + +L R++
Sbjct 690 PNMKEVSNELERIR 703
>sp|Q9LFV3|CRLK2_ARATH Calcium/calmodulin-regulated receptor-like
kinase 2 OS=Arabidopsis thaliana OX=3702 GN=CRLK2 PE=2 SV=1
Length=436
Score = 229 bits (585), Expect = 9e-65, Method: Composition-based stats.
Identities = 74/314 (24%), Positives = 124/314 (39%), Gaps = 30/314 (10%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
P + K LG+G FG V GE+ A K Q +
Sbjct 102 PRYNYKDIQKATQNFTTVLGQGSFGPVYKAV-----MPNGELAAAKV-HGSNSSQGDREF 155
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQL 1000
+ E+ +L L+H +++ G C D+ + L+ E++ GSL + L + +
Sbjct 156 QTEVSLLGRLHHRNLVNLTGYCVDKSHR--MLIYEFMSNGSLENLLYGGEGMQVLNWEER 213
Query 1001 LLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
L A I G+ YLH IHRDL + N+LLD+ K+ DFGL+K + R+
Sbjct 214 LQIALDISHGIEYLHEGAVPPVIHRDLKSANILLDHSMRAKVADFGLSKEMVLD----RM 269
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
+ P + K+ SD++SFGV + EL+T P +E I +A
Sbjct 270 TSGLKGTHGYMDPTYISTNKYTMKSDIYSFGVIILELITAI----HPQQNLMEYINLA-- 323
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE--- 1174
M+ + E+L++ + + + C RP+ + + + +
Sbjct 324 SMSPDGIDEILDQKLVGNASIEEVRLLAKIANRCVHKTPRKRPSIGEVTQFILKIKQSRS 383
Query 1175 --KYQGQAPSVFSV 1186
+ Q S F V
Sbjct 384 RGRRQDTMSSSFGV 397
Score = 206 bits (524), Expect = 1e-56, Method: Composition-based stats.
Identities = 56/373 (15%), Positives = 117/373 (31%), Gaps = 55/373 (15%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
+ + ++ + + + LGQG+ VY+ +
Sbjct 97 SASGIPRYNYKDIQKATQNFTTVLGQGSFGPVYKAVMPNGE------------------- 137
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
KV + F SL+ ++ H +L + G CV +++ E++
Sbjct 138 ------LAAAKVHGSNSSQGDREFQTEVSLLGRLHHRNLVNLTGYCVDKSHRMLIYEFMS 191
Query 692 HGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLG 746
+G L+ L G + W ++ +A ++ + YL ++H ++ NILL
Sbjct 192 NGSLENLLYGGEGMQVLNWEERLQIALDISHGIEYLHEGAVPPVIHRDLKSANILLDH-- 249
Query 747 LAEGTSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
S K++D G+ + ++ P + N + D + FG
Sbjct 250 -----SMRAKVADFGLSKEMVLDRMTSGLKGTHGYMDPTYIST--NKYTMKSDIYSFGVI 302
Query 804 LLEICFDGEAPLQ--------SRSPSEKEHFYQRQ--HRLPEPSCPQLATLTSQCLTYEP 853
+LE+ S SP + ++ LA + ++C+ P
Sbjct 303 ILELITAIHPQQNLMEYINLASMSPDGIDEILDQKLVGNASIEEVRLLAKIANRCVHKTP 362
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE---GHFGK 910
+RPS + + + +++ S + G
Sbjct 363 RKRPSIGEVTQFILKIKQSRSRGRRQDTMSSSFGVGYEEDLSRVMSRIKDQHVELGLLAG 422
Query 911 VSLYCYDPTNDGT 923
V + N T
Sbjct 423 VKEENHQERNIAT 435
>sp|Q9LEU7|CIPK5_ARATH CBL-interacting serine/threonine-protein
kinase 5 OS=Arabidopsis thaliana OX=3702 GN=CIPK5 PE=1 SV=1
Length=445
Score = 230 bits (586), Expect = 9e-65, Method: Composition-based stats.
Identities = 67/270 (25%), Positives = 110/270 (41%), Gaps = 27/270 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD---CGPQHRSGWKQEIDILRTLYHEHI 959
LG+G F KV GE VA+K + D P K+EI I++ + H +I
Sbjct 18 LGKGTFAKVYYG----KEIIGGECVAIKVINKDQVMKRPGMMEQIKREISIMKLVRHPNI 73
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
++ K + + + VME+V G L + + + + QQ+ + Y H++
Sbjct 74 VELKEVMATKTK--IFFVMEFVKGGELFCKISKGKLHEDAARRYFQQLISAVDYCHSRGV 131
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
HRDL N+LLD + +KI DFGL+ + + + +P + APE LK+ +
Sbjct 132 SHRDLKPENLLLDENGDLKISDFGLSALPEQILQDGLLHTQCGTPA-YVAPEVLKKKGYD 190
Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+D+WS GV LY LL C Q + M + R + P
Sbjct 191 GAKADIWSCGVVLYVLLAGCLPFQD------------ENLMNMYRKIFRAD----FEFPP 234
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
E L+ + R + ++
Sbjct 235 WFSPEARRLISKLLVVDPDRRISIPAIMRT 264
Score = 186 bits (471), Expect = 2e-49, Method: Composition-based stats.
Identities = 57/332 (17%), Positives = 104/332 (31%), Gaps = 44/332 (13%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
RV + LG+GT VY G+ + G V +K
Sbjct 6 RVLFGKYEMGRLLGKGTFAKVYYGKEIIGGEC------------------------VAIK 41
Query 643 VLDPSH----HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V++ + S+M V H ++ + V + V E+V+ G L +
Sbjct 42 VINKDQVMKRPGMMEQIKREISIMKLVRHPNIVELKEVMATKTKIFFVMEFVKGGEL--F 99
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ +G + QQL SA+ Y ++ + H ++ N+LL G +K+S
Sbjct 100 CKISKGKLHEDAARRYFQQLISAVDYCHSRGVSHRDLKPENLLLDENGD-------LKIS 152
Query 759 DPGVGLGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
D G+ + ++APE L D W G L +
Sbjct 153 DFGLSALPEQILQDGLLHTQCGTPAYVAPEVLKKKGYD-GAKADIWSCGVVLYVLLAGCL 211
Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
+ ++ P P+ L S+ L +P +R S I+R +
Sbjct 212 PFQDENLMNMYRKIFRADFEFPPWFSPEARRLISKLLVVDPDRRISIPAIMRTPWLRKNF 271
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
++ + + +
Sbjct 272 TPPLAFKIDEPICSQSSKNNEEEEEDGDCENQ 303
>sp|A8R7E6|CERK1_ARATH Chitin elicitor receptor kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=CERK1 PE=1 SV=1
Length=617
Score = 235 bits (599), Expect = 9e-65, Method: Composition-based stats.
Identities = 69/291 (24%), Positives = 117/291 (40%), Gaps = 30/291 (10%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+G+G FG V GE A+K + + Q + E+ +L +
Sbjct 320 DNFNLSFKIGQGGFGAVYYAELR------GEKAAIKKMDMEASKQ----FLAELKVLTRV 369
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGM 1011
+H ++++ G C E SL LV EYV G+L +L R + + + A G+
Sbjct 370 HHVNLVRLIGYCV---EGSLFLVYEYVENGNLGQHLHGSGREPLPWTKRVQIALDSARGL 426
Query 1012 AYLHAQHY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
Y+H +HRD+ + N+L+D K+ DFGL K G R +
Sbjct 427 EYIHEHTVPVYVHRDIKSANILIDQKFRAKVADFGLTKLTEVGGSATR---GAMGTFGYM 483
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR----- 1123
APE + + DV++FGV LYEL++ + E G+ +
Sbjct 484 APETV-YGEVSAKVDVYAFGVVLYELISAKGAVVKMTEAVGEFRGLVGVFEESFKETDKE 542
Query 1124 --LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
L ++++ P ++ L K C + A RP+ ++ L T+
Sbjct 543 EALRKIIDPRLGDSYPFDSVYKMAELGKACTQENAQLRPSMRYIVVALSTL 593
Score = 198 bits (504), Expect = 2e-52, Method: Composition-based stats.
Identities = 52/233 (22%), Positives = 88/233 (38%), Gaps = 48/233 (21%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+GQG VY LR E + +K +
Sbjct 318 ATDNFNLSFKIGQGGFGAVYYAELRGE--------------------------KAAIKKM 351
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-R 703
D + + F ++++V H +L + G CV G +V EYVE+G L L R
Sbjct 352 D---MEASKQFLAELKVLTRVHHVNLVRLIGYCVEGS-LFLVYEYVENGNLGQHLHGSGR 407
Query 704 GHVPMAWKMVVAQQLASALSYLENKNL---VHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+P ++ +A A L Y+ + VH ++ NIL+ + A K++D
Sbjct 408 EPLPWTKRVQIALDSARGLEYIHEHTVPVYVHRDIKSANILIDQKFRA-------KVADF 460
Query 761 GVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
G+ G + + ++APE + G +S +D + FG L E+
Sbjct 461 GLTKLTEVGGSATRGAMGTFGYMAPETVYG---EVSAKVDVYAFGVVLYELIS 510
>sp|Q9FX99|Y1497_ARATH Probable receptor-like protein kinase At1g49730
OS=Arabidopsis thaliana OX=3702 GN=At1g49730 PE=2 SV=1
Length=663
Score = 236 bits (602), Expect = 9e-65, Method: Composition-based stats.
Identities = 69/301 (23%), Positives = 120/301 (40%), Gaps = 15/301 (5%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935
+ +G+G FG V + G + AVK +
Sbjct 306 HEDDSSSAFRKFSYKEMTNATNDFNTVIGQGGFGTVYKAEF-----NDGLIAAVKKMNK- 359
Query 936 CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---R 992
Q + +EI +L L+H +++ KG C ++ E+ LV +Y+ GSL+D+L +
Sbjct 360 VSEQAEQDFCREIGLLAKLHHRNLVALKGFCINKKER--FLVYDYMKNGSLKDHLHAIGK 417
Query 993 HSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
+ A + + YLH HRD+ + N+LLD + + K+ DFGLA +
Sbjct 418 PPPSWGTRMKIAIDVANALEYLHFYCDPPLCHRDIKSSNILLDENFVAKLSDFGLAHSSR 477
Query 1050 EGHEYYR-VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
+G + V D + PE + + SDV+S+GV L EL+T +
Sbjct 478 DGSVCFEPVNTDIRGTPGYVDPEYVVTQELTEKSDVYSYGVVLLELITGRRAVDEGRNLV 537
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
+ L L + + K V +++ C E E RP+ + ++ +
Sbjct 538 EMSQRFLLAKSKHLELVDPRIKDSINDAGGKQLDAVVTVVRLCTEKEGRSRPSIKQVLRL 597
Query 1169 L 1169
L
Sbjct 598 L 598
Score = 211 bits (537), Expect = 3e-56, Method: Composition-based stats.
Identities = 57/322 (18%), Positives = 108/322 (34%), Gaps = 62/322 (19%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
+ + S+ + + +GQG VY+
Sbjct 307 EDDSSSAFRKFSYKEMTNATNDFNTVIGQGGFGTVYKA---------------------- 344
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+ L +K ++ F L++++ H +L + G C+ E +V +
Sbjct 345 ---EFNDGLIAAVKKMNKVSEQAEQDFCREIGLLAKLHHRNLVALKGFCINKKERFLVYD 401
Query 689 YVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLAR 744
Y+++G L L + +M +A +A+AL YL + L H ++ NILL
Sbjct 402 YMKNGSLKDHLHAIGKPPPSWGTRMKIAIDVANALEYLHFYCDPPLCHRDIKSSNILLDE 461
Query 745 LGLAEGTSPFIKLSDPGVGLGALS--------REERVERIPWLAPECLPGGANSLSTAMD 796
+ KLSD G+ + + ++ PE + L+ D
Sbjct 462 -------NFVAKLSDFGLAHSSRDGSVCFEPVNTDIRGTPGYVDPEYVVT--QELTEKSD 512
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEK---------EHFYQRQHRLPE-------PSCPQ 840
+ +G LLE+ A + R+ E +H R+ +
Sbjct 513 VYSYGVVLLELITGRRAVDEGRNLVEMSQRFLLAKSKHLELVDPRIKDSINDAGGKQLDA 572
Query 841 LATLTSQCLTYEPTQRPSFRTI 862
+ T+ C E RPS + +
Sbjct 573 VVTVVRLCTEKEGRSRPSIKQV 594
>sp|O80719|Y2706_ARATH Probable receptor-like protein kinase At2g47060
OS=Arabidopsis thaliana OX=3702 GN=At2g47060 PE=1 SV=1
Length=365
Score = 227 bits (579), Expect = 9e-65, Method: Composition-based stats.
Identities = 71/284 (25%), Positives = 118/284 (42%), Gaps = 24/284 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG +G+V + A+K L D Q + + ++ ++ L H++ ++
Sbjct 79 IGEGSYGRVYYGVLNNDLPS-----AIKKL--DSNKQPDNEFLAQVSMVSRLKHDNFVQL 131
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------IGLAQLLLFAQQICEGMA 1012
G C D + L E+ GSL D L + Q + A G+
Sbjct 132 LGYCVDGNSRILS--YEFANNGSLHDILHGRKGVKGAQPGPVLSWYQRVKIAVGAARGLE 189
Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH + H IHRD+ + NVLL D + KI DF L+ P+ ++A
Sbjct 190 YLHEKANPHIIHRDIKSSNVLLFEDDVAKIADFDLSNQAPD-MAARLHSTRVLGTFGYHA 248
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVLRLTELL 1128
PE + SDV+SFGV L ELLT P L+ A +++ ++ + +
Sbjct 249 PEYAMTGQLNAKSDVYSFGVVLLELLTGRKPVDHRLPRGQQSLVTWATPKLSEDKVKQCV 308
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ P K ++ + C + EA FRP ++ L+ +
Sbjct 309 DARLGGDYPPKAVAKLAAVAALCVQYEADFRPNMSIVVKALQPL 352
Score = 204 bits (519), Expect = 9e-57, Method: Composition-based stats.
Identities = 56/279 (20%), Positives = 99/279 (35%), Gaps = 53/279 (19%)
Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
+ P + + S + + S +G+G+ VY G L
Sbjct 52 KLQPIEVPIIPFSELKEATDDFGSNSLIGEGSYGRVYYGVL------------------- 92
Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
+L +K LD + F S++S++ H + + G CV G I+
Sbjct 93 ------NNDLPSAIKKLDSN-KQPDNEFLAQVSMVSRLKHDNFVQLLGYCVDGNSRILSY 145
Query 688 EYVEHGPLDVWLRRERG--------HVPMAWKMVVAQQLASALSYLENK---NLVHGNVC 736
E+ +G L L +G + ++ +A A L YL K +++H ++
Sbjct 146 EFANNGSLHDILHGRKGVKGAQPGPVLSWYQRVKIAVGAARGLEYLHEKANPHIIHRDIK 205
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVG------LGALSREERVERIPWLAPECLPGGANS 790
N+LL +A K++D + L + + APE G
Sbjct 206 SSNVLLFEDDVA-------KIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTG--Q 256
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
L+ D + FG LLE+ G P+ R P ++
Sbjct 257 LNAKSDVYSFGVVLLELL-TGRKPVDHRLPRGQQSLVTW 294
>sp|Q1PEM5|PERK3_ARATH Proline-rich receptor-like protein kinase
PERK3 OS=Arabidopsis thaliana OX=3702 GN=PERK3 PE=2 SV=2
Length=513
Score = 232 bits (591), Expect = 9e-65, Method: Composition-based stats.
Identities = 73/279 (26%), Positives = 116/279 (42%), Gaps = 21/279 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG V G VAVK LK Q ++ E++I+ ++H +++
Sbjct 189 LGEGGFGFVYKGIL-----NNGNEVAVKQLKVG-SAQGEKEFQAEVNIISQIHHRNLVSL 242
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
G C ++ LV E+VP +L +L R ++ + L A +G++YLH
Sbjct 243 VGYCIAGAQR--LLVYEFVPNNTLEFHLHGKGRPTMEWSLRLKIAVSSSKGLSYLHENCN 300
Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ A N+L+D K+ DFGLAK + + + R + APE
Sbjct 301 PKIIHRDIKAANILIDFKFEAKVADFGLAKIALDTNTHVSTR--VMGTFGYLAPEYAASG 358
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQG----QMTVLRLTELLERG 1131
K SDV+SFGV L EL+T + L+ A+ + L +
Sbjct 359 KLTEKSDVYSFGVVLLELITGRRPVDANNVYADDSLVDWARPLLVQALEESNFEGLADIK 418
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ + C A RP + ++ +L+
Sbjct 419 LNNEYDREEMARMVACAAACVRYTARRRPRMDQVVRVLE 457
Score = 225 bits (573), Expect = 2e-62, Method: Composition-based stats.
Identities = 66/334 (20%), Positives = 116/334 (35%), Gaps = 50/334 (15%)
Query 513 AFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI--IMRGARAS 570
F L S S + G + F L C +P + L I
Sbjct 110 GFSLSPPSPSRLSTGAVVGISIGGGVFVLTLIFFL--CKKKRPRDDKALPAPIGLVLGIH 167
Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
T +L+ + ++ + LG+G VY+G L
Sbjct 168 QSTFTYGELA---RATNKFSEANLLGEGGFGFVYKGILNNGN------------------ 206
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
V +K L F +++SQ+ H +L + G C+ G + ++V E+V
Sbjct 207 -------EVAVKQLKVGSAQGEKEFQAEVNIISQIHHRNLVSLVGYCIAGAQRLLVYEFV 259
Query 691 EHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLG 746
+ L+ L + R + + ++ +A + LSYL ++H ++ NIL+
Sbjct 260 PNNTLEFHLHGKGRPTMEWSLRLKIAVSSSKGLSYLHENCNPKIIHRDIKAANILIDFKF 319
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFG 801
A K++D G+ AL V +LAPE G L+ D + FG
Sbjct 320 EA-------KVADFGLAKIALDTNTHVSTRVMGTFGYLAPEYAASG--KLTEKSDVYSFG 370
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
LLE+ + ++ + L +
Sbjct 371 VVLLELITGRRPVDANNVYADDSLVDWARPLLVQ 404
>sp|Q86AE1|Y9853_DICDI Probable serine/threonine-protein kinase
DDB_G0271538 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0271538
PE=3 SV=1
Length=527
Score = 232 bits (592), Expect = 1e-64, Method: Composition-based stats.
Identities = 76/293 (26%), Positives = 123/293 (42%), Gaps = 32/293 (11%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK--ADCGPQHRSGWKQEIDILRTLY 955
++G G FG+V Y T+ VAVK L P + +EI IL+ +
Sbjct 34 FMDVEIGRGSFGQVQKASYFGTD------VAVKQLSTLVSIDPDYFKFMLREIKILKGMR 87
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMA 1012
H +I++Y G C +G +V EY+ G L ++ +I + A I +
Sbjct 88 HPNIVQYIGACCHEG--RYMIVTEYIKGGDLHQFIKARGVSNISWTLRMKLALDIASAFS 145
Query 1013 YLHAQHYIHRDLAARNVLLDNDR----LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
YLH++ I RDL A+N+L+D K+ DFG A+ +G + + G
Sbjct 146 YLHSKKVIFRDLKAKNILVDEIGDGLYRAKVIDFGFARIF-DGKDTNNLTICGSENT--M 202
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
+PE + + + DV+S+GV L EL+ ++ + + L
Sbjct 203 SPEVIVGSSYNDSCDVYSYGVLLLELICGSRVVKTQLKR-----------TPMNAFDMNL 251
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
E+ E L P+ CP L K C RPTF+ ++ LK + + P
Sbjct 252 EKAEHLA-PESCPRAFMDLAKWCCSYNPKDRPTFKIVVEGLKVLTNQQLKDLP 303
Score = 201 bits (512), Expect = 4e-54, Method: Composition-based stats.
Identities = 57/306 (19%), Positives = 111/306 (36%), Gaps = 43/306 (14%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
F +D ++ +G+G+ V + V
Sbjct 24 DFSSLDYSDLFMDVEIGRGSFGQVQKASYFGTD--------------------------V 57
Query 640 VLKVLD---PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+K L D ++ + H ++ G C ++VTEY++ G L
Sbjct 58 AVKQLSTLVSIDPDYFKFMLREIKILKGMRHPNIVQYIGACCHEGRYMIVTEYIKGGDLH 117
Query 697 VWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+++ R ++ +M +A +ASA SYL +K ++ ++ +NIL+ +G
Sbjct 118 QFIKARGVSNISWTLRMKLALDIASAFSYLHSKKVIFRDLKAKNILVDEIG---DGLYRA 174
Query 756 KLSDPGVGLGALSREERVERIPW----LAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
K+ D G ++ I ++PE + G +S + + D + +G LLE+
Sbjct 175 KVIDFGFARIFDGKDTNNLTICGSENTMSPEVIVG--SSYNDSCDVYSYGVLLLELICGS 232
Query 812 EAPLQSRS----PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ + + +H PE L C +Y P RP+F+ ++ L
Sbjct 233 RVVKTQLKRTPMNAFDMNLEKAEHLAPESCPRAFMDLAKWCCSYNPKDRPTFKIVVEGLK 292
Query 868 RLQPHN 873
L
Sbjct 293 VLTNQQ 298
>sp|O43283|M3K13_HUMAN Mitogen-activated protein kinase kinase
kinase 13 OS=Homo sapiens OX=9606 GN=MAP3K13 PE=1 SV=1
Length=966
Score = 241 bits (616), Expect = 1e-64, Method: Composition-based stats.
Identities = 83/301 (28%), Positives = 122/301 (41%), Gaps = 35/301 (12%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ + + + D + +++ LG G G V L + E VA+K
Sbjct 142 WNIIGKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRA------EEVAIK 195
Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
++ I LR L H +II +KG C ++MEY G L + L
Sbjct 196 KVREQNETD--------IKHLRKLKHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVL 245
Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
I L+ ++ I GM YLH IHRDL + NVL+ + VKI DFG +K +
Sbjct 246 RAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELS 305
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
+ + V W APE ++ D+WSFGV L+ELLT P K +
Sbjct 306 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG-----EIPYKDV 356
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ I G + LP P CP LMK W+++ RP+F + L
Sbjct 357 DSSAIIWGVGSN---------SLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHL 407
Query 1170 K 1170
Sbjct 408 D 408
Score = 214 bits (546), Expect = 6e-56, Method: Composition-based stats.
Identities = 65/305 (21%), Positives = 109/305 (36%), Gaps = 50/305 (16%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+A L Q V +EI++L LG G + V+ G+ R E
Sbjct 146 GKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAE--------------- 190
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
V +K + + + ++ H ++ GVC + P ++
Sbjct 191 -----------EVAIKKVREQNE-------TDIKHLRKLKHPNIIAFKGVCTQAPCYCII 232
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
EY HG L LR R + + + +AS ++YL ++H ++ N+L+
Sbjct 233 MEYCAHGQLYEVLRAGR-KITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTD 291
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+K+SD G + ++ + W+APE + +S +D W FG
Sbjct 292 A-------VKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 342
Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
L E+ GE P + S +P L Q +P RPSFR
Sbjct 343 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFR 401
Query 861 TILRD 865
L
Sbjct 402 QTLMH 406
>sp|Q9LIG2|RLK6_ARATH Receptor-like protein kinase At3g21340 OS=Arabidopsis
thaliana OX=3702 GN=At3g21340 PE=1 SV=1
Length=899
Score = 240 bits (613), Expect = 1e-64, Method: Composition-based stats.
Identities = 65/295 (22%), Positives = 122/295 (41%), Gaps = 17/295 (6%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
+ + R LG+G FG V + T E VAVK L ++
Sbjct 579 NRRFTYSEVVTMTNNFERVLGKGGFGMVYHGTVNNT-----EQVAVKMLSHSSSQGYKE- 632
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQ 999
+K E+++L ++H++++ G C++ ++L L+ EY+ G LR+++ +
Sbjct 633 FKAEVELLLRVHHKNLVGLVGYCDEG--ENLALIYEYMANGDLREHMSGKRGGSILNWET 690
Query 1000 LLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
L + +G+ YLH +HRD+ N+LL+ K+ DFGL+++ P E +
Sbjct 691 RLKIVVESAQGLEYLHNGCKPPMVHRDVKTTNILLNEHLHAKLADFGLSRSFPIEGETHV 750
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
+P + PE + SDV+SFG+ L E++T+ K +
Sbjct 751 STVVAGTP-GYLDPEYYRTNWLNEKSDVYSFGIVLLEIITNQLVINQSREK-PHIAEWVG 808
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+T + +++ L +C ++ RPT ++ L
Sbjct 809 LMLTKGDIQNIMDPKLYGDYDSGSVWRAVELAMSCLNPSSARRPTMSQVVIELNE 863
Score = 218 bits (555), Expect = 3e-57, Method: Composition-based stats.
Identities = 71/337 (21%), Positives = 116/337 (34%), Gaps = 61/337 (18%)
Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
+ S + +R + ++ T N + ++ V LG+G VY G +
Sbjct 556 PSSYTQVSEVRTIRSSESAIMTKN-RRFTYSEVVTMTNNFERVLGKGGFGMVYHGTVNNT 614
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
+V +K+L S F L+ +V H +L
Sbjct 615 E-------------------------QVAVKMLSHSSSQGYKEFKAEVELLLRVHHKNLV 649
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN-- 727
+ G C G ++ EY+ +G L + +RG + W ++ + + A L YL N
Sbjct 650 GLVGYCDEGENLALIYEYMANGDLREHMSGKRGGSILNWETRLKIVVESAQGLEYLHNGC 709
Query 728 -KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERV-----ERIPWLA 780
+VH +V NILL KL+D G+ + E V +L
Sbjct 710 KPPMVHRDVKTTNILLNE-------HLHAKLADFGLSRSFPIEGETHVSTVVAGTPGYLD 762
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR---SPSEKEHFYQRQHRLPEPS 837
PE N L+ D + FG LLEI + QSR +E + +
Sbjct 763 PEYYRT--NWLNEKSDVYSFGIVLLEIITNQLVINQSREKPHIAEWVGLMLTKGDIQNIM 820
Query 838 CPQLA------------TLTSQCLTYEPTQRPSFRTI 862
P+L L CL +RP+ +
Sbjct 821 DPKLYGDYDSGSVWRAVELAMSCLNPSSARRPTMSQV 857
>sp|Q13308|PTK7_HUMAN Inactive tyrosine-protein kinase 7 OS=Homo
sapiens OX=9606 GN=PTK7 PE=1 SV=2
Length=1070
Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats.
Identities = 91/335 (27%), Positives = 145/335 (43%), Gaps = 30/335 (9%)
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
+CL P Q +++ L T S + L+ I LG+
Sbjct 746 MECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATNKRHSTSDKMHFPRSS-LQPITTLGK 804
Query 906 GHFGKVSLYCYDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG 964
FG+V L +G E +V VK+L Q + +++E+++ L H ++++ G
Sbjct 805 SEFGEVFLAKAQGLEEGVAETLVLVKSL-QSKDEQQQLDFRRELEMFGKLNHANVVRLLG 863
Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQLLLFAQQICEGMAYL 1014
C + +V+EYV LG L+ +L + Q + Q+ GM +L
Sbjct 864 LCREAEPH--YMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALCTQVALGMEHL 921
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
++H+DLAARN L+ R VK+ GL+K V Y+ P+ W +PE +
Sbjct 922 SNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHF--RQAWVPLRWMSPEAIL 979
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
E F SDVW+FGV ++E+ TH + GQ L +L RL
Sbjct 980 EGDFSTKSDVWAFGVLMWEVFTHGEMPHG-------------GQADDEVLADLQAGKARL 1026
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P+P+ CP ++Y LM+ CW RP+F + L
Sbjct 1027 PQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 1061
Score = 220 bits (560), Expect = 2e-57, Method: Composition-based stats.
Identities = 77/338 (23%), Positives = 128/338 (38%), Gaps = 47/338 (14%)
Query 544 CFSLRRCCLPQPG-ETSNLIIMRGARASPRTLN--LSQLSFHRVDQKEITQLSHLGQGTR 600
C + QP E + + + P N S + + ++ LG+
Sbjct 748 CLNGGPLQNGQPSAEIQEEVALTSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEF 807
Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660
V+ + + G E V++K L L F
Sbjct 808 GEVFLAKAQGLEEGVA-------------------ETLVLVKSLQSKDEQQQLDFRRELE 848
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH------VPMAWKMVV 714
+ +++H ++ + G+C + MV EYV+ G L +LR + P++ K V
Sbjct 849 MFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKV 908
Query 715 AQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
A Q+A + +L N VH ++ RN L++ +K+S G+ + E
Sbjct 909 ALCTQVALGMEHLSNNRFVHKDLAARNCLVS-------AQRQVKVSALGLSKDVYNSEYY 961
Query 773 VER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HF 826
R + W++PE + G ST D W FG + E+ GE P ++ E
Sbjct 962 HFRQAWVPLRWMSPEAILEG--DFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADL 1019
Query 827 YQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862
+ RLP+P CP +L L +C P RPSF I
Sbjct 1020 QAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEI 1057
>sp|Q9JI11|STK4_MOUSE Serine/threonine-protein kinase 4 OS=Mus
musculus OX=10090 GN=Stk4 PE=1 SV=1
Length=487
Score = 231 bits (589), Expect = 1e-64, Method: Composition-based stats.
Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K
Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+K C R T L+
Sbjct 250 WSDNFMDFVKQCLVKSPEQRATATQLLQ 277
Score = 203 bits (516), Expect = 5e-55, Method: Composition-based stats.
Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L + S + ++ L LG+G+ +VY+ + G
Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K + + S+M Q H+ +G + + +V EY G +
Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + Q L YL +H ++ NILL G
Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163
Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D GV R + W+APE + + D W G T +E+ +G
Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220
Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P P R PE QCL P QR + +L+
Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFMDFVKQCLVKSPEQRATATQLLQHPF 280
>sp|Q9FZB8|Y5181_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g51810 OS=Arabidopsis thaliana OX=3702
GN=At1g51810 PE=1 SV=1
Length=871
Score = 240 bits (612), Expect = 1e-64, Method: Composition-based stats.
Identities = 72/335 (21%), Positives = 128/335 (38%), Gaps = 20/335 (6%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
L C+ + L + + T+ + + L
Sbjct 527 LMIFCVVRKNNPSNDEAPTSCM---LPADSRSSEPTIVTKNKKFTYAEVLTMTNNFQKIL 583
Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963
G+G FG V + T E VAVK L Q +K E+++L ++H++++
Sbjct 584 GKGGFGIVYYGSVNGT-----EQVAVKMLSH-SSAQGYKQFKAEVELLLRVHHKNLVGLV 637
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQH- 1018
G CE+ + L L+ EY+ G L +++ + L A + +G+ YLH
Sbjct 638 GYCEEGDK--LALIYEYMANGDLDEHMSGKRGGSILNWGTRLKIALEAAQGLEYLHNGCK 695
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRD+ N+LL+ K+ DFGL+++ P E + V + + PE +
Sbjct 696 PLMVHRDVKTTNILLNEHFDTKLADFGLSRSFPIEGETH-VSTVVAGTIGYLDPEYYRTN 754
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
SDV+SFGV L ++T+ K + G +T + + +
Sbjct 755 WLTEKSDVYSFGVVLLVMITNQPVIDQNREK-RHIAEWVGGMLTKGDIKSITDPNLLGDY 813
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ L +C + RPT ++ LK
Sbjct 814 NSGSVWKAVELAMSCMNPSSMTRPTMSQVVFELKE 848
Score = 212 bits (540), Expect = 2e-55, Method: Composition-based stats.
Identities = 70/352 (20%), Positives = 116/352 (33%), Gaps = 63/352 (18%)
Query 540 AGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL---SQLSFHRVDQKEITQLSHLG 596
F + R P E ++ S + + ++ V LG
Sbjct 525 VALMIFCVVRKNNPSNDEAPTSCMLPADSRSSEPTIVTKNKKFTYAEVLTMTNNFQKILG 584
Query 597 QGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFY 656
+G VY G + +V +K+L S F
Sbjct 585 KGGFGIVYYGSVNGTE-------------------------QVAVKMLSHSSAQGYKQFK 619
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVV 714
L+ +V H +L + G C G + ++ EY+ +G LD + +RG + W ++ +
Sbjct 620 AEVELLLRVHHKNLVGLVGYCEEGDKLALIYEYMANGDLDEHMSGKRGGSILNWGTRLKI 679
Query 715 AQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSRE 770
A + A L YL N +VH +V NILL KL+D G+ + E
Sbjct 680 ALEAAQGLEYLHNGCKPLMVHRDVKTTNILLNE-------HFDTKLADFGLSRSFPIEGE 732
Query 771 ERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
V I +L PE N L+ D + FG LL + + Q+R
Sbjct 733 THVSTVVAGTIGYLDPEYYRT--NWLTEKSDVYSFGVVLLVMITNQPVIDQNREKRHIAE 790
Query 826 F---YQRQHRLPEPSCPQL------------ATLTSQCLTYEPTQRPSFRTI 862
+ + + + P L L C+ RP+ +
Sbjct 791 WVGGMLTKGDIKSITDPNLLGDYNSGSVWKAVELAMSCMNPSSMTRPTMSQV 842
>sp|P04412|EGFR_DROME Epidermal growth factor receptor OS=Drosophila
melanogaster OX=7227 GN=Egfr PE=1 SV=3
Length=1426
Score = 244 bits (623), Expect = 1e-64, Method: Composition-based stats.
Identities = 90/269 (33%), Positives = 137/269 (51%), Gaps = 20/269 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG+V + P + VA+K L G + + +E I+ + H +++K
Sbjct 944 LGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKL 1003
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
C + L+ + +PLG L DY+ R IG LL ++ QI +GM+YL + +
Sbjct 1004 LAVCMSS---QMMLITQLMPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLV 1060
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLAARNVL+ LVKI DFGLAK + Y+ G P+ W A EC++ F
Sbjct 1061 HRDLAARNVLVQTPSLVKITDFGLAKLLSSDSNEYKA-AGGKMPIKWLALECIRNRVFTS 1119
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVW+FGVT++ELLT + + +L+E G +L +P+ C
Sbjct 1120 KSDVWAFGVTIWELLTFGQR--------------PHENIPAKDIPDLIEVGLKLEQPEIC 1165
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPIL 1169
++Y + +CW +A+ RPTF+ L +
Sbjct 1166 SLDIYCTLLSCWHLDAAMRPTFKQLTTVF 1194
Score = 223 bits (567), Expect = 9e-58, Method: Composition-based stats.
Identities = 65/301 (22%), Positives = 120/301 (40%), Gaps = 39/301 (13%)
Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
P + + V E+ + LG G VY+G EG
Sbjct 920 PSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPEGENV--------------- 964
Query 631 RDRGQELRVVLK-VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
++ V +K +L + + + F A +M+ H +L + VC+ + +++T+
Sbjct 965 -----KIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKLLAVCM-SSQMMLITQL 1018
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
+ G L ++R R + + + Q+A +SYLE K LVH ++ RN+L+
Sbjct 1019 MPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLV------- 1071
Query 750 GTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGAT 803
T +K++D G+ S + I WLA EC+ ++ D W FG T
Sbjct 1072 QTPSLVKITDFGLAKLLSSDSNEYKAAGGKMPIKWLALECIRNRV--FTSKSDVWAFGVT 1129
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRT 861
+ E+ G+ P ++ + + +L PE + C + RP+F+
Sbjct 1130 IWELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLSCWHLDAAMRPTFKQ 1189
Query 862 I 862
+
Sbjct 1190 L 1190
>sp|Q13043|STK4_HUMAN Serine/threonine-protein kinase 4 OS=Homo
sapiens OX=9606 GN=STK4 PE=1 SV=2
Length=487
Score = 231 bits (589), Expect = 1e-64, Method: Composition-based stats.
Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K
Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+K C R T L+
Sbjct 250 WSDNFTDFVKQCLVKSPEQRATATQLLQ 277
Score = 203 bits (516), Expect = 6e-55, Method: Composition-based stats.
Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L + S + ++ L LG+G+ +VY+ + G
Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K + + S+M Q H+ +G + + +V EY G +
Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + Q L YL +H ++ NILL G
Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163
Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D GV R + W+APE + + D W G T +E+ +G
Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220
Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P P R PE QCL P QR + +L+
Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPF 280
>sp|Q9LV48|PERK1_ARATH Proline-rich receptor-like protein kinase
PERK1 OS=Arabidopsis thaliana OX=3702 GN=PERK1 PE=1 SV=1
Length=652
Score = 235 bits (600), Expect = 1e-64, Method: Composition-based stats.
Identities = 78/298 (26%), Positives = 126/298 (42%), Gaps = 24/298 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V +G+ VAVK LKA G R ++ E++I+ ++H H++
Sbjct 286 LGQGGFGYVHKGIL-----PSGKEVAVKQLKAGSGQGERE-FQAEVEIISRVHHRHLVSL 339
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH---A 1016
G C ++ LV E+VP +L +L R ++ + L A +G++YLH
Sbjct 340 IGYCMAGVQR--LLVYEFVPNNNLEFHLHGKGRPTMEWSTRLKIALGSAKGLSYLHEDCN 397
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ A N+L+D K+ DFGLAK + + + R + APE
Sbjct 398 PKIIHRDIKASNILIDFKFEAKVADFGLAKIASDTNTHVSTR--VMGTFGYLAPEYAASG 455
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVL----RLTELLERG 1131
K SDV+SFGV L EL+T + L+ A+ + L +
Sbjct 456 KLTEKSDVFSFGVVLLELITGRRPVDANNVYVDDSLVDWARPLLNRASEEGDFEGLADSK 515
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK---TVHEKYQGQAPSVFSV 1186
+ + C A RP ++ L+ ++ + +G P +V
Sbjct 516 MGNEYDREEMARMVACAAACVRHSARRRPRMSQIVRALEGNVSLSDLNEGMRPGHSNV 573
Score = 221 bits (564), Expect = 7e-60, Method: Composition-based stats.
Identities = 59/259 (23%), Positives = 98/259 (38%), Gaps = 47/259 (18%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
S T +LS ++ + LGQG V++G L
Sbjct 264 SKSTFTYEELS---RATNGFSEANLLGQGGFGYVHKGILPSGK----------------- 303
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
V +K L F ++S+V H HL + G C+ G + ++V E+
Sbjct 304 --------EVAVKQLKAGSGQGEREFQAEVEIISRVHHRHLVSLIGYCMAGVQRLLVYEF 355
Query 690 VEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745
V + L+ L + R + + ++ +A A LSYL ++H ++ NIL+
Sbjct 356 VPNNNLEFHLHGKGRPTMEWSTRLKIALGSAKGLSYLHEDCNPKIIHRDIKASNILIDFK 415
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800
A K++D G+ A V +LAPE G L+ D + F
Sbjct 416 FEA-------KVADFGLAKIASDTNTHVSTRVMGTFGYLAPEYAASG--KLTEKSDVFSF 466
Query 801 GATLLEICFDGEAPLQSRS 819
G LLE+ G P+ + +
Sbjct 467 GVVLLELI-TGRRPVDANN 484
>sp|A4K2Y1|STK4_CHLAE Serine/threonine-protein kinase 4 OS=Chlorocebus
aethiops OX=9534 GN=STK4 PE=3 SV=1
Length=487
Score = 231 bits (588), Expect = 1e-64, Method: Composition-based stats.
Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K
Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+K C R T L+
Sbjct 250 WSDNFTDFVKQCLVKSPEQRATATQLLQ 277
Score = 202 bits (515), Expect = 6e-55, Method: Composition-based stats.
Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L + S + ++ L LG+G+ +VY+ + G
Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K + + S+M Q H+ +G + + +V EY G +
Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + Q L YL +H ++ NILL G
Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163
Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D GV R + W+APE + + D W G T +E+ +G
Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220
Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P P R PE QCL P QR + +L+
Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPF 280
>sp|A4K2T0|STK4_MACMU Serine/threonine-protein kinase 4 OS=Macaca
mulatta OX=9544 GN=STK4 PE=3 SV=1
Length=487
Score = 231 bits (588), Expect = 1e-64, Method: Composition-based stats.
Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K
Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+K C R T L+
Sbjct 250 WSDNFTDFVKQCLVKSPEQRATATQLLQ 277
Score = 202 bits (515), Expect = 6e-55, Method: Composition-based stats.
Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L + S + ++ L LG+G+ +VY+ + G
Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K + + S+M Q H+ +G + + +V EY G +
Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + Q L YL +H ++ NILL G
Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163
Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D GV R + W+APE + + D W G T +E+ +G
Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220
Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P P R PE QCL P QR + +L+
Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPF 280
>sp|Q8VYT3|Y4052_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At4g30520 OS=Arabidopsis thaliana OX=3702
GN=At4g30520 PE=1 SV=1
Length=648
Score = 235 bits (600), Expect = 1e-64, Method: Composition-based stats.
Identities = 75/274 (27%), Positives = 121/274 (44%), Gaps = 15/274 (5%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V G G MVAVK LK G S ++ E++++ H+++++
Sbjct 309 LGAGGFGNVYRG-----KLGDGTMVAVKRLKDINGTSGDSQFRMELEMISLAVHKNLLRL 363
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ---H 1018
G C GE+ LV Y+P GS+ L + ++ A G+ YLH Q
Sbjct 364 IGYCATSGER--LLVYPYMPNGSVASKLKSKPALDWNMRKRIAIGAARGLLYLHEQCDPK 421
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ A N+LLD +GDFGLAK + + V V APE L +
Sbjct 422 IIHRDVKAANILLDECFEAVVGDFGLAKLLNHADSH--VTTAVRGTVGHIAPEYLSTGQS 479
Query 1079 YYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+DV+ FG+ L EL+T + ++ ++ + +++ ELL+R
Sbjct 480 SEKTDVFGFGILLLELITGLRALEFGKTVSQKGAMLEWVRKLHEEMKVEELLDRELGTNY 539
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
E+ + C + + RP ++ +L+
Sbjct 540 DKIEVGEMLQVALLCTQYLPAHRPKMSEVVLMLE 573
Score = 190 bits (482), Expect = 2e-49, Method: Composition-based stats.
Identities = 65/320 (20%), Positives = 107/320 (33%), Gaps = 64/320 (20%)
Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
NL +F V + + LG G NVY G+L
Sbjct 287 NLRSFTFRELHVYTDGFSSKNILGAGGFGNVYRGKL------------------------ 322
Query 633 RGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
G V +K L + F ++S H +L + G C E ++V Y+
Sbjct 323 -GDGTMVAVKRLKDINGTSGDSQFRMELEMISLAVHKNLLRLIGYCATSGERLLVYPYMP 381
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748
+G + L + + + + +A A L YL + ++H +V NILL A
Sbjct 382 NGSVASKL-KSKPALDWNMRKRIAIGAARGLLYLHEQCDPKIIHRDVKAANILLDECFEA 440
Query 749 EGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+ D G+ + V + +APE L G + S D +GFG
Sbjct 441 V-------VGDFGLAKLLNHADSHVTTAVRGTVGHIAPEYLSTGQS--SEKTDVFGFGIL 491
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS------------------CPQLATLT 845
LLE+ A ++ S+K + +L E ++ +
Sbjct 492 LLELITGLRALEFGKTVSQKGAMLEWVRKLHEEMKVEELLDRELGTNYDKIEVGEMLQVA 551
Query 846 SQCLTYEPTQRPSFRTILRD 865
C Y P RP ++
Sbjct 552 LLCTQYLPAHRPKMSEVVLM 571
>sp|A4K2M3|STK4_PAPAN Serine/threonine-protein kinase 4 OS=Papio
anubis OX=9555 GN=STK4 PE=3 SV=1
Length=487
Score = 231 bits (588), Expect = 1e-64, Method: Composition-based stats.
Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K
Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 146 IHRDIKAGNILLNTEGQAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+K C R T L+
Sbjct 250 WSDNFTDFVKQCLVKSPEQRATATQLLQ 277
Score = 203 bits (516), Expect = 5e-55, Method: Composition-based stats.
Identities = 60/300 (20%), Positives = 97/300 (32%), Gaps = 44/300 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L + S + ++ L LG+G+ +VY+ + G
Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K + + S+M Q H+ +G + + +V EY G +
Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + Q L YL +H ++ NILL G A
Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGQA------- 163
Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D GV R + W+APE + + D W G T +E+ +G
Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220
Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P P R PE QCL P QR + +L+
Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPF 280
>sp|Q9SX31|PERK9_ARATH Proline-rich receptor-like protein kinase
PERK9 OS=Arabidopsis thaliana OX=3702 GN=PERK9 PE=1 SV=1
Length=708
Score = 236 bits (603), Expect = 1e-64, Method: Composition-based stats.
Identities = 72/283 (25%), Positives = 116/283 (41%), Gaps = 20/283 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG V G +VAVK LK G R +K E++ L ++H H++
Sbjct 383 LGEGGFGCVYKGIL-----PDGRVVAVKQLKIGGGQGDRE-FKAEVETLSRIHHRHLVSI 436
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLH---AQ 1017
G C + L+ +YV L +L + + A + A G+AYLH
Sbjct 437 VGHCISGDRR--LLIYDYVSNNDLYFHLHGEKSVLDWATRVKIAAGAARGLAYLHEDCHP 494
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
IHRD+ + N+LL+++ ++ DFGLA+ + + + R + APE K
Sbjct 495 RIIHRDIKSSNILLEDNFDARVSDFGLARLALDCNTHITTR--VIGTFGYMAPEYASSGK 552
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQG----QMTVLRLTELLERGE 1132
SDV+SFGV L EL+T S P L+ A+ + L +
Sbjct 553 LTEKSDVFSFGVVLLELITGRKPVDTSQPLGDESLVEWARPLISHAIETEEFDSLADPKL 612
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+ + C A+ RP ++ +++ +
Sbjct 613 GGNYVESEMFRMIEAAGACVRHLATKRPRMGQIVRAFESLAAE 655
Score = 225 bits (573), Expect = 1e-60, Method: Composition-based stats.
Identities = 60/315 (19%), Positives = 107/315 (34%), Gaps = 44/315 (14%)
Query 527 RELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ 586
++ + R+ F ++ + S + S +
Sbjct 316 GDVTPSPMSSTARSDSAFFRMQSSAPVGASKRSGSYQSQSGGLGNSKALFSYEELVK-AT 374
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+Q + LG+G VY+G L V +K L
Sbjct 375 NGFSQENLLGEGGFGCVYKGILPDGR-------------------------VVAVKQLKI 409
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
F +S++ H HL + G C+ G +++ +YV + L L E+ +
Sbjct 410 GGGQGDREFKAEVETLSRIHHRHLVSIVGHCISGDRRLLIYDYVSNNDLYFHLHGEKSVL 469
Query 707 PMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
A ++ +A A L+YL ++H ++ NILL + ++SD G+
Sbjct 470 DWATRVKIAAGAARGLAYLHEDCHPRIIHRDIKSSNILL-------EDNFDARVSDFGLA 522
Query 764 LGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
AL + ++APE G L+ D + FG LLE+ G P+ +
Sbjct 523 RLALDCNTHITTRVIGTFGYMAPEYASSG--KLTEKSDVFSFGVVLLELI-TGRKPVDTS 579
Query 819 SPSEKEHFYQRQHRL 833
P E + L
Sbjct 580 QPLGDESLVEWARPL 594
>sp|O23081|CRK41_ARATH Cysteine-rich receptor-like protein kinase
41 OS=Arabidopsis thaliana OX=3702 GN=CRK41 PE=3 SV=2
Length=665
Score = 236 bits (601), Expect = 1e-64, Method: Composition-based stats.
Identities = 73/282 (26%), Positives = 117/282 (41%), Gaps = 18/282 (6%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+ LGEG FG V D GE +AVK L G Q + + E+ ++ L H +
Sbjct 346 RDNQLGEGGFGAVYKGVLD-----YGEEIAVKRLSMKSG-QGDNEFINEVSLVAKLQHRN 399
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYL 1014
+++ G C QGE+ + L+ E+ SL Y+ R + + G+ YL
Sbjct 400 LVRLLGFCL-QGEERI-LIYEFFKNTSLDHYIFDSNRRMILDWETRYRIISGVARGLLYL 457
Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY-RVREDGDSPVFWYAP 1070
H +HRD+ A NVLLD+ KI DFG+AK R + AP
Sbjct 458 HEDSRFKIVHRDMKASNVLLDDAMNPKIADFGMAKLFDTDQTSQTRFTSKVAGTYGYMAP 517
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQMTVLRLTELLE 1129
E +F +DV+SFGV + E++ ++ SP L L+ + +++
Sbjct 518 EYAMSGEFSVKTDVFSFGVLVLEIIKGKKNNWSPEEDSSLFLLSYVWKSWREGEVLNIVD 577
Query 1130 RGERLPRP-DKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ H+ C + A RPT +++ +L
Sbjct 578 PSLVETIGVSDEIMKCIHIGLLCVQENAESRPTMASVVVMLN 619
Score = 219 bits (558), Expect = 6e-59, Method: Composition-based stats.
Identities = 56/266 (21%), Positives = 103/266 (39%), Gaps = 52/266 (20%)
Query 572 RTLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+ L QL F + + ++ + LG+G VY+G L
Sbjct 325 KDAQLLQLDFDTIRLATNDFSRDNQLGEGGFGAVYKGVL--------------------- 363
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
D G+E + +K L F SL++++ H +L + G C++G E I++ E+
Sbjct 364 --DYGEE--IAVKRLSMKSGQGDNEFINEVSLVAKLQHRNLVRLLGFCLQGEERILIYEF 419
Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744
++ LD ++ + + W + + +A L YL +VH ++ N+LL
Sbjct 420 FKNTSLDHYIFDSNRRMILDWETRYRIISGVARGLLYLHEDSRFKIVHRDMKASNVLLD- 478
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER--------VERIPWLAPECLPGGANSLSTAMD 796
+ K++D G+ + + ++APE G S D
Sbjct 479 ------DAMNPKIADFGMAKLFDTDQTSQTRFTSKVAGTYGYMAPEYAMSG--EFSVKTD 530
Query 797 KWGFGATLLEICFDGEAPLQSRSPSE 822
+ FG +LEI + + SP E
Sbjct 531 VFSFGVLVLEIIKGKK---NNWSPEE 553
>sp|Q9ZUE0|PEK12_ARATH Proline-rich receptor-like protein kinase
PERK12 OS=Arabidopsis thaliana OX=3702 GN=PERK12 PE=2 SV=2
Length=720
Score = 237 bits (604), Expect = 1e-64, Method: Composition-based stats.
Identities = 76/279 (27%), Positives = 119/279 (43%), Gaps = 21/279 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LGEG FG V G++VAVK LKA G R +K E++I+ ++H H++
Sbjct 377 LGEGGFGCVYKGTLQ-----DGKVVAVKQLKAGSGQGDRE-FKAEVEIISRVHHRHLVSL 430
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAYLH---A 1016
G C + L+ EYV +L +L + ++ + A +G+AYLH
Sbjct 431 VGYCISDQHR--LLIYEYVSNQTLEHHLHGKGLPVLEWSKRVRIAIGSAKGLAYLHEDCH 488
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ + N+LLD++ ++ DFGLA+ + R + APE
Sbjct 489 PKIIHRDIKSANILLDDEYEAQVADFGLARLNDTTQTHVSTR--VMGTFGYLAPEYASSG 546
Query 1077 KFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQG----QMTVLRLTELLERG 1131
K SDV+SFGV L EL+T Q+ P L+ A+ + L+EL++
Sbjct 547 KLTDRSDVFSFGVVLLELVTGRKPVDQTQPLGEESLVEWARPLLLKAIETGDLSELIDTR 606
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ + C RP ++ L
Sbjct 607 LEKRYVEHEVFRMIETAAACVRHSGPKRPRMVQVVRALD 645
Score = 217 bits (553), Expect = 5e-58, Method: Composition-based stats.
Identities = 66/365 (18%), Positives = 122/365 (33%), Gaps = 49/365 (13%)
Query 481 YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGW--GRSFPSVRELGAALQGCLL 538
+ L ++ + D + P L G G+ + S
Sbjct 262 GVVFLVRRKKKRNIDSYNHSQYLPHPNFSVKSDGFLYGQDPGKGYSSGPNGSMYNNSQQQ 321
Query 539 RAG-DDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQ 597
++ + + P S+ S +T + S + + + + LG+
Sbjct 322 QSSMGNSYGTAGGGYPHHQMQSSGTPDSAILGSGQT-HFSYEELAEI-TQGFARKNILGE 379
Query 598 GTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE 657
G VY+G L+ V +K L F
Sbjct 380 GGFGCVYKGTLQDGK-------------------------VVAVKQLKAGSGQGDREFKA 414
Query 658 TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQ 716
++S+V H HL + G C+ +++ EYV + L+ L + + + ++ +A
Sbjct 415 EVEIISRVHHRHLVSLVGYCISDQHRLLIYEYVSNQTLEHHLHGKGLPVLEWSKRVRIAI 474
Query 717 QLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
A L+YL ++H ++ NILL A+ ++D G+ + + V
Sbjct 475 GSAKGLAYLHEDCHPKIIHRDIKSANILLDDEYEAQ-------VADFGLARLNDTTQTHV 527
Query 774 -----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
+LAPE G L+ D + FG LLE+ G P+ P +E +
Sbjct 528 STRVMGTFGYLAPEYASSG--KLTDRSDVFSFGVVLLELV-TGRKPVDQTQPLGEESLVE 584
Query 829 RQHRL 833
L
Sbjct 585 WARPL 589
>sp|Q8RY17|WAKLI_ARATH Wall-associated receptor kinase-like 22
OS=Arabidopsis thaliana OX=3702 GN=WAKL22 PE=2 SV=1
Length=751
Score = 237 bits (605), Expect = 1e-64, Method: Composition-based stats.
Identities = 71/291 (24%), Positives = 118/291 (41%), Gaps = 26/291 (9%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R LG+G G V G +VAVK K + E+ +L +
Sbjct 419 DNFNMNRVLGQGGQGTVYKGML-----VDGRIVAVKRSKV-LDEDKVEEFINEVGVLSQI 472
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEG 1010
H +I+K GCC + E + LV E++P G L L +++ L + +I
Sbjct 473 NHRNIVKLMGCCLE-TEVPI-LVYEHIPNGDLFKRLHHDSDDYTMTWDVRLRISVEIAGA 530
Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+AYLH+ HRD+ N+LLD K+ DFG ++++ + + +
Sbjct 531 LAYLHSAASTPVYHRDVKTTNILLDEKYRAKVSDFGTSRSINVDQTH--LTTLVAGTFGY 588
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTE 1126
PE + +F SDV+SFGV L EL+T P + L+ M R+ +
Sbjct 589 LDPEYFQTSQFTDKSDVYSFGVVLVELITGEKPFSVMRPEENRGLVSHFNEAMKQNRVLD 648
Query 1127 LLERGERLPRPDKCPCE----VYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+++ + + C E V L + C + RP + L+ +
Sbjct 649 IVDSRIK----EGCTLEQVLAVAKLARRCLSLKGKKRPNMREVSVELERIR 695
Score = 221 bits (563), Expect = 4e-59, Method: Composition-based stats.
Identities = 72/369 (20%), Positives = 127/369 (34%), Gaps = 66/369 (18%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
L G S + + +L LGQG + VY+G L
Sbjct 393 KQQLTTRGGNVQSSKIFSSKELEK---ATDNFNMNRVLGQGGQGTVYKGMLVDGRI---- 445
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
V +K D F ++SQ++H ++ + G C
Sbjct 446 ---------------------VAVKRSKVLDEDKVEEFINEVGVLSQINHRNIVKLMGCC 484
Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVH 732
+ I+V E++ +G L L + M W ++ ++ ++A AL+YL + + H
Sbjct 485 LETEVPILVYEHIPNGDLFKRLHHDSDDYTMTWDVRLRISVEIAGALAYLHSAASTPVYH 544
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGG 787
+V NILL A K+SD G + +L PE
Sbjct 545 RDVKTTNILLDEKYRA-------KVSDFGTSRSINVDQTHLTTLVAGTFGYLDPEYFQT- 596
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE----KEHFY--QRQHRLPEPSCPQL 841
+ + D + FG L+E+ GE P P E HF +Q+R+ + ++
Sbjct 597 -SQFTDKSDVYSFGVVLVELI-TGEKPFSVMRPEENRGLVSHFNEAMKQNRVLDIVDSRI 654
Query 842 ------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
A L +CL+ + +RP+ R + +L R++ L + +
Sbjct 655 KEGCTLEQVLAVAKLARRCLSLKGKKRPNMREVSVELERIRSSPEDLELHIEEEDEEECA 714
Query 890 TVFHKRYLK 898
+
Sbjct 715 MEINMDDSW 723
>sp|Q9FNE1|CRK42_ARATH Cysteine-rich receptor-like protein kinase
42 OS=Arabidopsis thaliana OX=3702 GN=CRK42 PE=2 SV=1
Length=651
Score = 235 bits (599), Expect = 1e-64, Method: Composition-based stats.
Identities = 80/308 (26%), Positives = 126/308 (41%), Gaps = 23/308 (7%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935
+ + Y + LG+G G V L G+ VAVK L
Sbjct 294 RKFNNSKTKFKYETLEKATDYFSHKKMLGQGGNGTVFLGIL-----PNGKNVAVKRL-VF 347
Query 936 CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS- 994
+ E++++ + H++++K GC + E LV EYVP SL +L S
Sbjct 348 NTRDWVEEFFNEVNLISGIQHKNLVKLLGCSIEGPES--LLVYEYVPNKSLDQFLFDESQ 405
Query 995 ---IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ +Q L EG+AYLH IHRD+ NVLLD+ KI DFGLA+
Sbjct 406 SKVLNWSQRLNIILGTAEGLAYLHGGSPVRIIHRDIKTSNVLLDDQLNPKIADFGLARCF 465
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
G + + + + APE + + +DV+SFGV + E+ + P +
Sbjct 466 --GLDKTHLSTGIAGTLGYMAPEYVVRGQLTEKADVYSFGVLVLEIACGTRINAFVP-ET 522
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPR-----PDKCPCEVYHLMKNCWETEASFRPTFE 1163
L+ T+ RL E L+ + + C+V + C + S RP+ E
Sbjct 523 GHLLQRVWNLYTLNRLVEALDPCLKDEFLQVQGSEAEACKVLRVGLLCTQASPSLRPSME 582
Query 1164 NLIPILKT 1171
+I +L
Sbjct 583 EVIRMLTE 590
Score = 215 bits (547), Expect = 1e-57, Method: Composition-based stats.
Identities = 70/357 (20%), Positives = 120/357 (34%), Gaps = 68/357 (19%)
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615
E NL ++ + +T + + LGQG V+ G L +
Sbjct 284 QEKRNLGLVSRKFNNSKTK--FKYETLEKATDYFSHKKMLGQGGNGTVFLGILPNGKN-- 339
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675
V +K L + D F+ +L+S + H +L + G
Sbjct 340 -----------------------VAVKRLVFNTRDWVEEFFNEVNLISGIQHKNLVKLLG 376
Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRE--RGHVPMAWKMVVAQQLASALSYLENK---NL 730
+ GPE+++V EYV + LD +L E + + ++ + A L+YL +
Sbjct 377 CSIEGPESLLVYEYVPNKSLDQFLFDESQSKVLNWSQRLNIILGTAEGLAYLHGGSPVRI 436
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLP 785
+H ++ N+LL K++D G+ + + ++APE +
Sbjct 437 IHRDIKTSNVLLDDQLNP-------KIADFGLARCFGLDKTHLSTGIAGTLGYMAPEYVV 489
Query 786 GGANSLSTAMDKWGFGATLLEICFDGE----APLQSRSPSEKEHFYQRQHRLPEPSCPQL 841
G L+ D + FG +LEI P + Y +RL E P L
Sbjct 490 RG--QLTEKADVYSFGVLVLEIACGTRINAFVPETGHLLQRVWNLYT-LNRLVEALDPCL 546
Query 842 ATLTSQ-----------------CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
Q C P+ RPS ++R LT +
Sbjct 547 KDEFLQVQGSEAEACKVLRVGLLCTQASPSLRPSMEEVIRMLTERDYPIPSPTSPPF 603
>sp|Q8RY67|WAKLO_ARATH Wall-associated receptor kinase-like 14
OS=Arabidopsis thaliana OX=3702 GN=WAKL14 PE=2 SV=2
Length=708
Score = 236 bits (603), Expect = 2e-64, Method: Composition-based stats.
Identities = 71/283 (25%), Positives = 122/283 (43%), Gaps = 20/283 (7%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+ LG G +G V E VA+K L+ + EI +L ++ H +++
Sbjct 352 QKLGIGAYGTVYRGKLQ-----NDEWVAIKRLRHRDS-ESLDQVMNEIKLLSSVSHPNLV 405
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQ 1017
+ GCC +QG+ LV EY+P G+L ++L R + L A Q + +AYLH+
Sbjct 406 RLLGCCIEQGDP--VLVYEYMPNGTLSEHLQRDRGSGLPWTLRLTVATQTAKAIAYLHSS 463
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
HRD+ + N+LLD D K+ DFGL++ + G + P+ +
Sbjct 464 MNPPIYHRDIKSTNILLDYDFNSKVADFGLSRLGMTESSHISTAPQG--TPGYLDPQYHQ 521
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ SDV+SFGV L E++T + P + L +A ++ + E+++
Sbjct 522 CFHLSDKSDVYSFGVVLAEIITGLKVVDFTRPHTEINLAALAVDKIGSGCIDEIIDPILD 581
Query 1134 LPRPDKCPCEVY---HLMKNCWETEASFRPTFENLIPILKTVH 1173
L ++ L C + RPT + L+ +
Sbjct 582 LDLDAWTLSSIHTVAELAFRCLAFHSDMRPTMTEVADELEQIR 624
Score = 209 bits (532), Expect = 2e-55, Method: Composition-based stats.
Identities = 67/360 (19%), Positives = 123/360 (34%), Gaps = 64/360 (18%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
RR P S ++ A + + ++ LG G VY G+
Sbjct 308 RRRSTPLRSHLSAKRLLSEAAGNSSVAFFPYKEIEK-ATDGFSEKQKLGIGAYGTVYRGK 366
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667
L+ + V +K L + L+S VSH
Sbjct 367 LQNDEW-------------------------VAIKRLRHRDSESLDQVMNEIKLLSSVSH 401
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLE 726
+L + G C+ + ++V EY+ +G L L+R+RG +P ++ VA Q A A++YL
Sbjct 402 PNLVRLLGCCIEQGDPVLVYEYMPNGTLSEHLQRDRGSGLPWTLRLTVATQTAKAIAYLH 461
Query 727 NK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPW 778
+ + H ++ NILL K++D G+ ++ + +
Sbjct 462 SSMNPPIYHRDIKSTNILLD-------YDFNSKVADFGLSRLGMTESSHISTAPQGTPGY 514
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838
L P+ LS D + FG L EI + +R +E ++
Sbjct 515 LDPQY--HQCFHLSDKSDVYSFGVVLAEIITGLKVVDFTRPHTEINLAALAVDKIGSGCI 572
Query 839 PQL--------------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
++ A L +CL + RP+ + +L +++ +
Sbjct 573 DEIIDPILDLDLDAWTLSSIHTVAELAFRCLAFHSDMRPTMTEVADELEQIRLSGWIPSM 632
>sp|P83104|M3K7L_DROME Putative mitogen-activated protein kinase
kinase kinase 7-like OS=Drosophila melanogaster OX=7227 GN=Takl1
PE=2 SV=1
Length=393
Score = 227 bits (579), Expect = 2e-64, Method: Composition-based stats.
Identities = 75/292 (26%), Positives = 125/292 (43%), Gaps = 38/292 (13%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG G G V + + +AVK + ++EI L + HE++I+
Sbjct 16 FLGAGSGGAVRKATFQ------NQEIAVKIFD-FLEETIKKNAEREITHLSEIDHENVIR 68
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA-- 1016
G K L+MEY+ GSL +YL + + Q + +A Q + +AYLH+
Sbjct 69 VIG--RASNGKKDYLLMEYLEEGSLHNYLYGDDKWEYTVEQAVRWALQCAKALAYLHSLD 126
Query 1017 QHYIHRDLAARNVLL-DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ +HRD+ +N+LL + +KI DFGLA + + D + + APE +K
Sbjct 127 RPIVHRDIKPQNMLLYNQHEDLKICDFGLATDMSNN------KTDMQGTLRYMAPEAIKH 180
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
K+ DV+SFG+ L+EL+T + + + + GE+LP
Sbjct 181 LKYTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQYA-----------IMKAISSGEKLP 229
Query 1136 RP---DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
CP + LM+ C + RP+ + + L E+Y+ F
Sbjct 230 MEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIEKFL---GEQYESGTDEDF 278
Score = 180 bits (457), Expect = 3e-48, Method: Composition-based stats.
Identities = 58/302 (19%), Positives = 113/302 (37%), Gaps = 50/302 (17%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
+ Q+ F V E LG G+ V + Q
Sbjct 2 VKQVDFAEVKLSE----KFLGAGSGGAVRKATF--------------------------Q 31
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+ +K+ D I + +S++ H ++ V G G ++ ++ EY+E G L
Sbjct 32 NQEIAVKIFDFLEETIKKNAEREITHLSEIDHENVIRVIGRASNGKKDYLLMEYLEEGSL 91
Query 696 DVWLR-RERGHVPMAWKMVVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGLAEGTS 752
+L ++ + + A Q A AL+YL + + +VH ++ +N+LL
Sbjct 92 HNYLYGDDKWEYTVEQAVRWALQCAKALAYLHSLDRPIVHRDIKPQNMLLYNQHED---- 147
Query 753 PFIKLSDPGVGLGALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
+K+ D G+ + + + + ++APE + + D + FG L E+
Sbjct 148 --LKICDFGLATDMSNNKTDMQGTLRYMAPEAIKH--LKYTAKCDVYSFGIMLWELMTRQ 203
Query 812 EAPLQSRSPSEKEHFYQR---QHRLP----EPSCPQ-LATLTSQCLTYEPTQRPSFRTIL 863
+P+ + + +LP CP+ + L C+ P +RPS + I
Sbjct 204 LPYSHLENPNSQYAIMKAISSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIE 263
Query 864 RD 865
+
Sbjct 264 KF 265
>sp|Q00526|CDK3_HUMAN Cyclin-dependent kinase 3 OS=Homo sapiens
OX=9606 GN=CDK3 PE=1 SV=1
Length=305
Score = 224 bits (571), Expect = 2e-64, Method: Composition-based stats.
Identities = 72/292 (25%), Positives = 127/292 (43%), Gaps = 30/292 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y N TG++VA+K ++ D + S +EI +L+
Sbjct 1 MDMFQKVEKIGEGTYGVV----YKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009
L H +I++ E+ L LV E++ L+ Y+ P + L + + Q+ +
Sbjct 57 ELKHPNIVRLLDVV--HNERKLYLVFEFLSQ-DLKKYMDSTPGSELPLHLIKSYLFQLLQ 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
G+++ H+ IHRDL +N+L++ +K+ DFGLA+A Y +++ A
Sbjct 114 GVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTY---THEVVTLWYRA 170
Query 1070 PECLKEYK-FYYASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIGIAQGQMTVLR 1123
PE L K + A D+WS G E++T DS + ++G T
Sbjct 171 PEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSED-TWPG 229
Query 1124 LTELLERGERLP---------RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+T+L + P E L+ + + S R T + +
Sbjct 230 VTQLPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTAL 281
Score = 169 bits (429), Expect = 2e-45, Method: Composition-based stats.
Identities = 49/263 (19%), Positives = 93/263 (35%), Gaps = 40/263 (15%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--VLDP 646
++ +G+GT VY+ + R G V LK LD
Sbjct 4 FQKVEKIGEGTYGVVYKAKNRETGQ------------------------LVALKKIRLDL 39
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH- 705
+ SL+ ++ H ++ + V + +V E++ L ++ G
Sbjct 40 EMEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEFLSQ-DLKKYMDSTPGSE 98
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+P+ QL +S+ + ++H ++ +N+L+ LG IKL+D G+
Sbjct 99 LPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGA-------IKLADFGLARA 151
Query 766 ----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ V + + APE L G +TA+D W G E+
Sbjct 152 FGVPLRTYTHEVVTLWYRAPEILLGSKF-YTTAVDIWSIGCIFAEMVTRKALFPGDSEID 210
Query 822 EKEHFYQRQHRLPEPSCPQLATL 844
+ ++ E + P + L
Sbjct 211 QLFRIFRMLGTPSEDTWPGVTQL 233
>sp|Q852Q0|OSK3_ORYSJ Serine/threonine protein kinase OSK3 OS=Oryza
sativa subsp. japonica OX=39947 GN=OSK3 PE=1 SV=1
Length=508
Score = 231 bits (589), Expect = 2e-64, Method: Composition-based stats.
Identities = 74/280 (26%), Positives = 109/280 (39%), Gaps = 30/280 (11%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQE 947
+ R LG G FGKV + + TG VA+K L + K+E
Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKRE 65
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006
I ILR H HII+ + + +VMEY G L DY+ + + + QQ
Sbjct 66 IKILRLFIHPHIIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQ 123
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I G+ Y H +HRDL N+LLD+ VK+ DFGL+ + +G + ++ SP
Sbjct 124 IISGVEYCHRNMVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDG---HFLKTSCGSPN- 179
Query 1067 WYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+ APE + + DVWS GV LY LL + L
Sbjct 180 YAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE---------------NIPNLF 224
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ ++ G P L+ + R T +
Sbjct 225 KKIKGGI-YTLPSHLSALARDLIPRMLVVDPMKRITIREI 263
Score = 182 bits (463), Expect = 8e-48, Method: Composition-based stats.
Identities = 53/332 (16%), Positives = 101/332 (30%), Gaps = 39/332 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
H K LG G+ V ++ G RV +
Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKIAEHKLTGH------------------------RVAI 45
Query 642 KVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
K+L+ + ++ ++ H H+ ++ V + +V EY + G L +
Sbjct 46 KILNRRQMRNMEMEEKAKREIKILRLFIHPHIIRLYEVIYTPTDIYVVMEYCKFGELFDY 105
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ E+G + + QQ+ S + Y +VH ++ N+LL +KL+
Sbjct 106 I-VEKGRLQEDEARRIFQQIISGVEYCHRNMVVHRDLKPENLLLDSK-------YNVKLA 157
Query 759 DPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
D G+ + + APE + G + +D W G L +
Sbjct 158 DFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYALLCGTLPFD 216
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
P+ + + LP L + L +P +R + R I
Sbjct 217 DENIPNLFKKIKGGIYTLPSHLSALARDLIPRMLVVDPMKRITIREIREHQWFQIRLPRY 276
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
+ + + G+ H
Sbjct 277 LAVPPPDTAQQAKMIDEDTLQDVVNLGYGKDH 308
>sp|A2XFF4|OSK3_ORYSI Serine/threonine protein kinase OSK3 OS=Oryza
sativa subsp. indica OX=39946 GN=OSK3 PE=3 SV=1
Length=508
Score = 231 bits (589), Expect = 2e-64, Method: Composition-based stats.
Identities = 74/280 (26%), Positives = 109/280 (39%), Gaps = 30/280 (11%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQE 947
+ R LG G FGKV + + TG VA+K L + K+E
Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKRE 65
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006
I ILR H HII+ + + +VMEY G L DY+ + + + QQ
Sbjct 66 IKILRLFIHPHIIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQ 123
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I G+ Y H +HRDL N+LLD+ VK+ DFGL+ + +G + ++ SP
Sbjct 124 IISGVEYCHRNMVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDG---HFLKTSCGSPN- 179
Query 1067 WYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+ APE + + DVWS GV LY LL + L
Sbjct 180 YAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE---------------NIPNLF 224
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ ++ G P L+ + R T +
Sbjct 225 KKIKGGI-YTLPSHLSALARDLIPRMLVVDPMKRITIREI 263
Score = 182 bits (463), Expect = 8e-48, Method: Composition-based stats.
Identities = 53/332 (16%), Positives = 101/332 (30%), Gaps = 39/332 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
H K LG G+ V ++ G RV +
Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKIAEHKLTGH------------------------RVAI 45
Query 642 KVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
K+L+ + ++ ++ H H+ ++ V + +V EY + G L +
Sbjct 46 KILNRRQMRNMEMEEKAKREIKILRLFIHPHIIRLYEVIYTPTDIYVVMEYCKFGELFDY 105
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ E+G + + QQ+ S + Y +VH ++ N+LL +KL+
Sbjct 106 I-VEKGRLQEDEARRIFQQIISGVEYCHRNMVVHRDLKPENLLLDSK-------YNVKLA 157
Query 759 DPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
D G+ + + APE + G + +D W G L +
Sbjct 158 DFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYALLCGTLPFD 216
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
P+ + + LP L + L +P +R + R I
Sbjct 217 DENIPNLFKKIKGGIYTLPSHLSALARDLIPRMLVVDPMKRITIREIREHQWFQIRLPRY 276
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
+ + + G+ H
Sbjct 277 LAVPPPDTAQQAKMIDEDTLQDVVNLGYGKDH 308
>sp|P18161|SPLB_DICDI Dual specificity protein kinase splB OS=Dictyostelium
discoideum OX=44689 GN=splB PE=2 SV=2
Length=1155
Score = 243 bits (619), Expect = 2e-64, Method: Composition-based stats.
Identities = 74/292 (25%), Positives = 127/292 (43%), Gaps = 34/292 (12%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEI 948
+ ++ I+ +GEG F +V + + VA+K LK Q + + +E+
Sbjct 846 YIIDINDIQFIQKVGEGAFSEVWEGWWKGIH------VAIKKLKIIGDEEQFKERFIREV 899
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSIGLAQLL 1001
L+ H++I+ + G C K ++ EY+ GSL + L P+ +L
Sbjct 900 QNLKKGNHQNIVMFIGACY----KPACIITEYMAGGSLYNILHNPNSSTPKVKYSFPLVL 955
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
A + G+ +LH+ +HRDL ++N+LLD +KI DFGL++
Sbjct 956 KMATDMALGLLHLHSITIVHRDLTSQNILLDELGNIKISDFGLSREKSREGSMTMTNGGI 1015
Query 1062 DSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
+P W PE K + DV+ F + ++E+LT F +L G
Sbjct 1016 CNP-RWRPPELTKNLGHYSEKVDVYCFSLVVWEILTG-------EIPFSDLDGS------ 1061
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
++ G R P P+ C E+ L+ CWE + + RP F ++ LK +
Sbjct 1062 -QASAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKLKEI 1112
Score = 211 bits (536), Expect = 3e-54, Method: Composition-based stats.
Identities = 65/307 (21%), Positives = 109/307 (36%), Gaps = 53/307 (17%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+D +I + +G+G + V+EG + + V +K
Sbjct 848 IDINDIQFIQKVGEGAFSEVWEGWWKG--------------------------IHVAIKK 881
Query 644 LD--PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
L F + + +H ++ G C + ++TEY+ G L L
Sbjct 882 LKIIGDEEQFKERFIREVQNLKKGNHQNIVMFIGACYK--PACIITEYMAGGSLYNILHN 939
Query 702 ERGHVP-----MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
P + +A +A L +L + +VH ++ +NILL LG IK
Sbjct 940 PNSSTPKVKYSFPLVLKMATDMALGLLHLHSITIVHRDLTSQNILLDELG-------NIK 992
Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+SD G+ W PE L S +D + F + EI
Sbjct 993 ISDFGLSREKSREGSMTMTNGGICNPRWRPPE-LTKNLGHYSEKVDVYCFSLVVWEIL-T 1050
Query 811 GEAPLQSRSPSE---KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
GE P S+ + + + +PE P+L L +QC +P RP F I+ L
Sbjct 1051 GEIPFSDLDGSQASAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKLK 1110
Query 868 RLQPHNL 874
+ +N
Sbjct 1111 EISWNNP 1117
>sp|P05625|RAF1_CHICK RAF proto-oncogene serine/threonine-protein
kinase OS=Gallus gallus OX=9031 GN=RAF1 PE=2 SV=1
Length=647
Score = 235 bits (599), Expect = 2e-64, Method: Composition-based stats.
Identities = 79/333 (24%), Positives = 135/333 (41%), Gaps = 35/333 (11%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
+ T P+ R + + +S + +G G F
Sbjct 305 WSQPKTPVPAQRERAPG----TNTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF 360
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
G V + VAVK LK D P+ ++ E+ +LR H +I+ + G
Sbjct 361 GTVYKGKWHG-------DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYM- 412
Query 968 DQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
+ +L +V ++ SL +L + QL+ A+Q +GM YLHA++ IHRD+
Sbjct 413 --TKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMK 470
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYAS 1082
+ N+ L VKIGDFGLA +V E + W APE ++ F + S
Sbjct 471 SNNIFLHEGLTVKIGDFGLATVKSRWSGSQQV-EQPTGSILWMAPEVIRMQDSNPFSFQS 529
Query 1083 DVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
DV+S+G+ LYEL+T + + ++G + +L + C
Sbjct 530 DVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYK------------NC 577
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
P + L+ +C + RP F ++ ++ +
Sbjct 578 PKAMKRLVADCLKKVREERPLFPQILSSIELLQ 610
Score = 223 bits (567), Expect = 3e-60, Method: Composition-based stats.
Identities = 71/367 (19%), Positives = 127/367 (35%), Gaps = 62/367 (17%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
R + N I RG R S + ++ E+ + +G G+ VY+G+
Sbjct 316 RERAPGTNTQEKNKIRPRGQRDSSY--------YWEIEASEVMLSTRIGSGSFGTVYKGK 367
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQ 664
+ V +K+L DP+ AF +++ +
Sbjct 368 WHGD---------------------------VAVKILKVVDPTPEQFQ-AFRNEVAVLRK 399
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
H ++ G + +VT++ E L L + M + +A+Q A + Y
Sbjct 400 TRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778
L KN++H ++ NI L +K+ D G+ G+ E+ I W
Sbjct 459 LHAKNIIHRDMKSNNIFLHEGL-------TVKIGDFGLATVKSRWSGSQQVEQPTGSILW 511
Query 779 LAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------ 831
+APE + +N S D + +G L E+ GE P + ++ F +
Sbjct 512 MAPEVIRMQDSNPFSFQSDVYSYGIVLYELM-TGELPYSHINNRDQIIFMVGRGYASPDL 570
Query 832 -RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
+L + + L + CL +RP F IL + LQ + + S
Sbjct 571 SKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSIELLQHSLPKINRSASEPSLHRASH 630
Query 891 VFHKRYL 897
Sbjct 631 TEDINSC 637
>sp|O81905|SD18_ARATH Receptor-like serine/threonine-protein kinase
SD1-8 OS=Arabidopsis thaliana OX=3702 GN=SD18 PE=1 SV=1
Length=850
Score = 239 bits (609), Expect = 2e-64, Method: Composition-based stats.
Identities = 73/289 (25%), Positives = 111/289 (38%), Gaps = 20/289 (7%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
LG+G FG V G+ +AVK L Q +K E+ ++
Sbjct 521 MATNNFSNANKLGQGGFGIVYKG-----KLLDGQEMAVKRLSK-TSVQGTDEFKNEVKLI 574
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQI 1007
L H ++++ CC D GEK L+ EY+ SL +L + I
Sbjct 575 ARLQHINLVRLLACCVDAGEK--MLIYEYLENLSLDSHLFDKSRNSKLNWQMRFDIINGI 632
Query 1008 CEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
G+ YLH IHRDL A N+LLD KI DFG+A+ R+
Sbjct 633 ARGLLYLHQDSRFRIIHRDLKASNILLDKYMTPKISDFGMARIFGRDETEANTRK-VVGT 691
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELL-THCDSSQSPPTKFLELIGIAQGQMTVLR 1123
+ +PE + F SDV+SFGV L E++ + + + L L+G +
Sbjct 692 YGYMSPEYAMDGIFSMKSDVFSFGVLLLEIISSKRNKGFYNSDRDLNLLGCVWRNWKEGK 751
Query 1124 LTELLERGERLPRP---DKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
E+++ + C + A RPT +I +L
Sbjct 752 GLEIIDPIITDSSSTFRQHEILRCIQIGLLCVQERAEDRPTMSLVILML 800
Score = 226 bits (575), Expect = 5e-60, Method: Composition-based stats.
Identities = 56/273 (21%), Positives = 94/273 (34%), Gaps = 47/273 (17%)
Query 569 ASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+ L L + F V + + LGQG VY+G+L
Sbjct 504 NNTDDLELPLMEFEEVAMATNNFSNANKLGQGGFGIVYKGKLLDGQ-------------- 549
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+ +K L + F L++++ H +L + CV E +++
Sbjct 550 -----------EMAVKRLSKTSVQGTDEFKNEVKLIARLQHINLVRLLACCVDAGEKMLI 598
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENK---NLVHGNVCGRNIL 741
EY+E+ LD L + + + W+M + +A L YL ++H ++ NIL
Sbjct 599 YEYLENLSLDSHLFDKSRNSKLNWQMRFDIINGIARGLLYLHQDSRFRIIHRDLKASNIL 658
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAM 795
L + K+SD G+ E V +++PE G S
Sbjct 659 LDKYMTP-------KISDFGMARIFGRDETEANTRKVVGTYGYMSPEYAMDGI--FSMKS 709
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
D + FG LLEI S +
Sbjct 710 DVFSFGVLLLEIISSKRNKGFYNSDRDLNLLGC 742
>sp|Q9C821|PEK15_ARATH Proline-rich receptor-like protein kinase
PERK15 OS=Arabidopsis thaliana OX=3702 GN=PERK15 PE=2 SV=1
Length=509
Score = 231 bits (588), Expect = 2e-64, Method: Composition-based stats.
Identities = 77/296 (26%), Positives = 127/296 (43%), Gaps = 29/296 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V G +VA+K LK+ G R ++ EI + ++H H++
Sbjct 149 LGQGGFGYVHRGVL-----VDGTLVAIKQLKSGSGQGERE-FQAEIQTISRVHHRHLVSL 202
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLH---A 1016
G C ++ LV E+VP +L +L + ++ + A +G+AYLH
Sbjct 203 LGYCITGAQR--LLVYEFVPNKTLEFHLHEKERPVMEWSKRMKIALGAAKGLAYLHEDCN 260
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ A N+L+D+ K+ DFGLA++ + + R + APE
Sbjct 261 PKTIHRDVKAANILIDDSYEAKLADFGLARSSLDTDTHVSTR--IMGTFGYLAPEYASSG 318
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
K SDV+S GV L EL+T P ++ A+ M + L + G
Sbjct 319 KLTEKSDVFSIGVVLLELITGRRPVDKSQPFADDDSIVDWAKPLM-IQALNDGNFDGLVD 377
Query 1135 PRPDKCPCEVYHL--MKNC----WETEASFRPTFENLIPILK---TVHEKYQGQAP 1181
PR + ++ + M C A RP ++ + ++ + +G AP
Sbjct 378 PRLEN-DFDINEMTRMVACAAASVRHSAKRRPKMSQIVRAFEGNISIDDLTEGAAP 432
Score = 224 bits (570), Expect = 6e-62, Method: Composition-based stats.
Identities = 64/275 (23%), Positives = 100/275 (36%), Gaps = 46/275 (17%)
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P + SN ++ +S NL + + LGQG V+ G L
Sbjct 111 PKDDSN--NLQQWSSSEIGQNLFTYEDLSKATSNFSNTNLLGQGGFGYVHRGVLVDG--- 165
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
V +K L F +S+V H HL +
Sbjct 166 ----------------------TLVAIKQLKSGSGQGEREFQAEIQTISRVHHRHLVSLL 203
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENK---NL 730
G C+ G + ++V E+V + L+ L +ER + + +M +A A L+YL
Sbjct 204 GYCITGAQRLLVYEFVPNKTLEFHLHEKERPVMEWSKRMKIALGAAKGLAYLHEDCNPKT 263
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLP 785
+H +V NIL+ S KL+D G+ +L + V +LAPE
Sbjct 264 IHRDVKAANILID-------DSYEAKLADFGLARSSLDTDTHVSTRIMGTFGYLAPEYAS 316
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
G L+ D + G LLE+ G P+ P
Sbjct 317 SG--KLTEKSDVFSIGVVLLELI-TGRRPVDKSQP 348
>sp|Q54XX5|Y9849_DICDI Probable serine/threonine-protein kinase
DDB_G0278535 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0278535
PE=3 SV=1
Length=848
Score = 239 bits (609), Expect = 2e-64, Method: Composition-based stats.
Identities = 76/340 (22%), Positives = 127/340 (37%), Gaps = 24/340 (7%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
+ TQ + + + V L+ LG G G
Sbjct 482 NKKVTQLSIESLKSNPPNSMDSTGSISSDDLKESLTNLEHWVIDHSELEYTLKLGSGSSG 541
Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
KV Y G+ VAVK LK+ +K+E I+ ++ + ++ + G C
Sbjct 542 KVYKGLYK------GKEVAVKVLKSITTQSQLEEFKKEFQIMGSIRSQFMVTFYGACI-- 593
Query 970 GEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHA--QHYIHRDLA 1025
E L +VMEY SL + ++ IG + F Q+ G+ LH +HRD
Sbjct 594 -EPKLCMVMEYCSRDSLYHVMNTKKYDIGWDRFFQFTMQMTLGVQCLHNWTPQIVHRDFK 652
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK--FYYASD 1083
+ N+L++ D K+ DFGL++ + + +PE + SD
Sbjct 653 SLNLLVNEDWECKVSDFGLSRF--NTADNLETLSKIRGTFAYCSPEVAVGNGSLYTTKSD 710
Query 1084 VWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
++S G+ +EL+T + + S P I + M + G R P P
Sbjct 711 IYSIGIVFWELVTRVINGEYSRPYSEYSHIKMDFQIMLNSK------EGLRPTLPQNTPP 764
Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182
+ L K C E + RP+ E +I L + +Y +
Sbjct 765 GLEALYKQCVNQEQTLRPSCEEIIETLNRLRHEYMSSKTT 804
Score = 181 bits (459), Expect = 2e-45, Method: Composition-based stats.
Identities = 63/319 (20%), Positives = 106/319 (33%), Gaps = 53/319 (17%)
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
+L+ L +D E+ LG G+ VY+G + +
Sbjct 515 SLTNLEHWVIDHSELEYTLKLGSGSSGKVYKGLYKGK----------------------- 551
Query 635 QELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
V +KVL F + +M + + +G C+ P+ MV EY
Sbjct 552 ---EVAVKVLKSITTQSQLEEFKKEFQIMGSIRSQFMVTFYGACIE-PKLCMVMEYCSRD 607
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGLAEGT 751
L + ++ + Q+ + L N +VH + N+L+
Sbjct 608 SLYHVMNTKKYDIGWDRFFQFTMQMTLGVQCLHNWTPQIVHRDFKSLNLLVNE------- 660
Query 752 SPFIKLSDPGVGLGALSR-----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
K+SD G+ + + + +PE G + +T D + G E
Sbjct 661 DWECKVSDFGLSRFNTADNLETLSKIRGTFAYCSPEVAVGNGSLYTTKSDIYSIGIVFWE 720
Query 807 ICFDGEAPLQSRSPSEKEHFYQR-----------QHRLPEPSCPQLATLTSQCLTYEPTQ 855
+ SR SE H + LP+ + P L L QC+ E T
Sbjct 721 LVTRVINGEYSRPYSEYSHIKMDFQIMLNSKEGLRPTLPQNTPPGLEALYKQCVNQEQTL 780
Query 856 RPSFRTILRDLTRLQPHNL 874
RPS I+ L RL+ +
Sbjct 781 RPSCEEIIETLNRLRHEYM 799
>sp|O81069|Y2899_ARATH Probable leucine-rich repeat receptor-like
protein kinase At2g28990 OS=Arabidopsis thaliana OX=3702
GN=At2g28990 PE=1 SV=1
Length=884
Score = 239 bits (610), Expect = 2e-64, Method: Composition-based stats.
Identities = 70/307 (23%), Positives = 123/307 (40%), Gaps = 17/307 (6%)
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931
HN + + + + LGEG FG V + E VAVK
Sbjct 552 HNSQSESSFTSKKIRFTYSEVQEMTNNFDKALGEGGFGVVYHGFVNVI-----EQVAVKL 606
Query 932 LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP 991
L Q +K E+++L ++H +++ G C++ + L L+ EY+P G L+ +L
Sbjct 607 LSQSSS-QGYKHFKAEVELLMRVHHINLVSLVGYCDEG--EHLALIYEYMPNGDLKQHLS 663
Query 992 RHS----IGLAQLLLFAQQICEGMAYLHAQHY---IHRDLAARNVLLDNDRLVKIGDFGL 1044
+ L G+ YLH +HRD+ N+LLD K+ DFGL
Sbjct 664 GKHGGFVLSWESRLKIVLDAALGLEYLHTGCVPPMVHRDIKTTNILLDQHLQAKLADFGL 723
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104
+++ P G+E +P + PE + SD++SFG+ L E++++ Q
Sbjct 724 SRSFPIGNEKNVSTVVAGTP-GYLDPEYYQTNWLTEKSDIYSFGIVLLEIISNRPIIQQS 782
Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
K ++ +T L +++ + L +C ++ RP
Sbjct 783 REK-PHIVEWVSFMITKGDLRSIMDPNLHQDYDIGSVWKAIELAMSCVSLSSARRPNMSR 841
Query 1165 LIPILKT 1171
++ LK
Sbjct 842 VVNELKE 848
Score = 212 bits (540), Expect = 2e-55, Method: Composition-based stats.
Identities = 68/324 (21%), Positives = 107/324 (33%), Gaps = 60/324 (19%)
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
S T + ++ V + LG+G VY G + V
Sbjct 553 NSQSESSFTSKKIRFTYSEVQEMTNNFDKALGEGGFGVVYHGFVNVIE------------ 600
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+V +K+L S F L+ +V H +L + G C G
Sbjct 601 -------------QVAVKLLSQSSSQGYKHFKAEVELLMRVHHINLVSLVGYCDEGEHLA 647
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNL---VHGNVCGRN 739
++ EY+ +G L L + G ++W ++ + A L YL + VH ++ N
Sbjct 648 LIYEYMPNGDLKQHLSGKHGGFVLSWESRLKIVLDAALGLEYLHTGCVPPMVHRDIKTTN 707
Query 740 ILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPECLPGGANSLST 793
ILL + A KL+D G+ +L PE N L+
Sbjct 708 ILLDQHLQA-------KLADFGLSRSFPIGNEKNVSTVVAGTPGYLDPEYYQT--NWLTE 758
Query 794 AMDKWGFGATLLEICFDGEAPLQSR---SPSEKEHFYQRQHRLPEPSCPQLA-------- 842
D + FG LLEI + QSR E F + L P L
Sbjct 759 KSDIYSFGIVLLEIISNRPIIQQSREKPHIVEWVSFMITKGDLRSIMDPNLHQDYDIGSV 818
Query 843 ----TLTSQCLTYEPTQRPSFRTI 862
L C++ +RP+ +
Sbjct 819 WKAIELAMSCVSLSSARRPNMSRV 842
>sp|C0LGI2|Y1677_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g67720 OS=Arabidopsis thaliana OX=3702
GN=At1g67720 PE=1 SV=1
Length=929
Score = 240 bits (612), Expect = 2e-64, Method: Composition-based stats.
Identities = 71/282 (25%), Positives = 118/282 (42%), Gaps = 18/282 (6%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+ +G G FG V G+ VAVK + AD + E+ +L ++H
Sbjct 607 NFSKKVGRGSFGSVYYGRMK-----DGKEVAVK-ITADPSSHLNRQFVTEVALLSRIHHR 660
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGMAY 1013
+++ G CE+ + LV EY+ GSL D+L + L AQ +G+ Y
Sbjct 661 NLVPLIGYCEEADRR--ILVYEYMHNGSLGDHLHGSSDYKPLDWLTRLQIAQDAAKGLEY 718
Query 1014 LH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
LH IHRD+ + N+LLD + K+ DFGL++ E + V V + P
Sbjct 719 LHTGCNPSIIHRDVKSSNILLDINMRAKVSDFGLSRQTEEDLTH--VSSVAKGTVGYLDP 776
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLRLTELLE 1129
E + SDV+SFGV L+ELL+ + L ++ A+ + + +++
Sbjct 777 EYYASQQLTEKSDVYSFGVVLFELLSGKKPVSAEDFGPELNIVHWARSLIRKGDVCGIID 836
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ V + C E RP + +I ++
Sbjct 837 PCIASNVKIESVWRVAEVANQCVEQRGHNRPRMQEVIVAIQD 878
Score = 221 bits (562), Expect = 5e-58, Method: Composition-based stats.
Identities = 57/299 (19%), Positives = 105/299 (35%), Gaps = 61/299 (20%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+G+G+ +VY GR++ V +K+
Sbjct 608 FSKKVGRGSFGSVYYGRMKDGK-------------------------EVAVKITADPSSH 642
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
+ F +L+S++ H +L + G C I+V EY+ +G L L + P+ W
Sbjct 643 LNRQFVTEVALLSRIHHRNLVPLIGYCEEADRRILVYEYMHNGSLGDHLHGSSDYKPLDW 702
Query 711 --KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
++ +AQ A L YL N +++H +V NILL + K+SD G+
Sbjct 703 LTRLQIAQDAAKGLEYLHTGCNPSIIHRDVKSSNILLD-------INMRAKVSDFGLSRQ 755
Query 766 ALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
V + +L PE + L+ D + FG L E+ +
Sbjct 756 TEEDLTHVSSVAKGTVGYLDPEYYA--SQQLTEKSDVYSFGVVLFELLSGKKPVSAEDFG 813
Query 821 SEKEHFYQRQHRLPEPSCP-----------------QLATLTSQCLTYEPTQRPSFRTI 862
E + + + + ++A + +QC+ RP + +
Sbjct 814 PELNIVHWARSLIRKGDVCGIIDPCIASNVKIESVWRVAEVANQCVEQRGHNRPRMQEV 872
>sp|O64782|SD129_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase SD1-29 OS=Arabidopsis thaliana OX=3702
GN=SD129 PE=1 SV=1
Length=805
Score = 238 bits (607), Expect = 2e-64, Method: Composition-based stats.
Identities = 70/297 (24%), Positives = 115/297 (39%), Gaps = 17/297 (6%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
+ LG+G FG V G+ + VK L A Q
Sbjct 474 NFFEMHTIRTATNNFSPSNKLGQGGFGPVYKG-----KLVDGKEIGVKRL-ASSSGQGTE 527
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLA 998
+ EI ++ L H ++++ G C D EK L+ E++ SL ++ + +
Sbjct 528 EFMNEITLISKLQHRNLVRLLGYCIDGEEK--LLIYEFMVNKSLDIFIFDPCLKFELDWP 585
Query 999 QLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ Q I G+ YLH IHRDL N+LLD+ KI DFGLA+ +G +Y
Sbjct 586 KRFNIIQGIARGLLYLHRDSRLRVIHRDLKVSNILLDDRMNPKISDFGLARMF-QGTQYQ 644
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE-LIGI 1114
+ + +PE F SD++SFGV + E+++ S+ + L+
Sbjct 645 DNTRRVVGTLGYMSPEYAWAGLFSEKSDIYSFGVLMLEIISGKRISRFIYGDESKGLLAY 704
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ LL+R + C + EA RP ++ +L +
Sbjct 705 TWDSWCETGGSNLLDRDLTDTCQAFEVARCVQIGLLCVQHEAVDRPNTLQVLSMLTS 761
Score = 229 bits (585), Expect = 1e-61, Method: Composition-based stats.
Identities = 56/256 (22%), Positives = 98/256 (38%), Gaps = 45/256 (18%)
Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
R +N ++ R + + LGQG VY+G+L
Sbjct 467 RQDVSGVNFFEMHTIRTATNNFSPSNKLGQGGFGPVYKGKL------------------- 507
Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
V G++ G +K L S F +L+S++ H +L + G C+ G E +++
Sbjct 508 VDGKEIG------VKRLASSSGQGTEEFMNEITLISKLQHRNLVRLLGYCIDGEEKLLIY 561
Query 688 EYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILL 742
E++ + LD+++ + W + + Q +A L YL ++H ++ NILL
Sbjct 562 EFMVNKSLDIFIFDPCLKFELDWPKRFNIIQGIARGLLYLHRDSRLRVIHRDLKVSNILL 621
Query 743 ARLGLAEGTSPFIKLSDPGVGL----GALSREER--VERIPWLAPECLPGGANSLSTAMD 796
K+SD G+ R V + +++PE G S D
Sbjct 622 D-------DRMNPKISDFGLARMFQGTQYQDNTRRVVGTLGYMSPEYAWAGL--FSEKSD 672
Query 797 KWGFGATLLEICFDGE 812
+ FG +LEI
Sbjct 673 IYSFGVLMLEIISGKR 688
>sp|Q8T2I8|SEPA_DICDI Serine/threonine-protein kinase sepA OS=Dictyostelium
discoideum OX=44689 GN=sepA PE=2 SV=1
Length=1167
Score = 242 bits (618), Expect = 2e-64, Method: Composition-based stats.
Identities = 73/267 (27%), Positives = 124/267 (46%), Gaps = 28/267 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIK 961
+G+G FG V Y + G+ VA+K + P+ + G EID+L+ L H +I+K
Sbjct 24 IGKGGFGTV----YQGLDIEDGDFVAIKQINLTKIPKDQLQGIMNEIDLLKNLNHANIVK 79
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
Y + + +L +V+EYV GSL + + + ++ +Q+ EG+ YLH Q +
Sbjct 80 YIKYV--KTKDNLYIVLEYVENGSLSGIIKKFGKFPETLVCVYIRQVLEGLVYLHEQGVV 137
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ N+L + +K+ DFG+A + +W APE ++
Sbjct 138 HRDIKGANILTTKEGKIKLADFGVATKFDD-----TSAAAVVGTPYWMAPEIIELNGATT 192
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SD+WS G T+ ELLT SPP L GQM L + + + P P+
Sbjct 193 KSDIWSVGCTVIELLTG-----SPPYYDL-------GQMPAL---FRIVQDDCPPLPEGI 237
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + C++ + + R + + L+
Sbjct 238 SPPLKDWLMQCFQKDPNLRISAQKLLK 264
Score = 204 bits (520), Expect = 3e-52, Method: Composition-based stats.
Identities = 64/280 (23%), Positives = 101/280 (36%), Gaps = 41/280 (15%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH--HDI 651
+G+G VY+G +G V +K ++ + D
Sbjct 23 VIGKGGFGTVYQGLDIEDGDF------------------------VAIKQINLTKIPKDQ 58
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711
L+ ++H ++ +V EYVE+G L +++ G P
Sbjct 59 LQGIMNEIDLLKNLNHANIVKYIKYVKTKDNLYIVLEYVENGSLSGIIKK-FGKFPETLV 117
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--GALSR 769
V +Q+ L YL + +VH ++ G NIL + G IKL+D GV S
Sbjct 118 CVYIRQVLEGLVYLHEQGVVHRDIKGANILTTKEG-------KIKLADFGVATKFDDTSA 170
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR--SPSEKEHFY 827
V W+APE + +T D W G T++E+ G P P+
Sbjct 171 AAVVGTPYWMAPEIIELNGA--TTKSDIWSVGCTVIELL-TGSPPYYDLGQMPALFRIVQ 227
Query 828 QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
LPE P L QC +P R S + +L+
Sbjct 228 DDCPPLPEGISPPLKDWLMQCFQKDPNLRISAQKLLKHKW 267
>sp|Q9FZB1|Y5188_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g51880 OS=Arabidopsis thaliana OX=3702
GN=At1g51880 PE=2 SV=1
Length=872
Score = 239 bits (609), Expect = 2e-64, Method: Composition-based stats.
Identities = 66/284 (23%), Positives = 119/284 (42%), Gaps = 18/284 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R LG+G FG V + T VAVK L Q +K E+++L +
Sbjct 564 MTNNFERVLGKGGFGTVYHGNLEDT------QVAVKMLSH-SSAQGYKEFKAEVELLLRV 616
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEG 1010
+H +++ G C+D +L L+ EY+ G L++ + + + A + +G
Sbjct 617 HHRNLVGLVGYCDDGD--NLALIYEYMANGDLKENMSGKRGGNVLTWENRMQIAVEAAQG 674
Query 1011 MAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH +HRD+ N+LL+ K+ DFGL+++ P E + +P +
Sbjct 675 LEYLHNGCTPPMVHRDVKTTNILLNERYGAKLADFGLSRSFPVDGESHVSTVVAGTP-GY 733
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
PE + SDV+SFGV L E++T+ + + + +T + +
Sbjct 734 LDPEYYRTNWLSEKSDVYSFGVVLLEIVTNQPVTDKTRER-THINEWVGSMLTKGDIKSI 792
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
L+ ++ L C ++ RPT +++ L
Sbjct 793 LDPKLMGDYDTNGAWKIVELALACVNPSSNRRPTMAHVVTELNE 836
Score = 213 bits (541), Expect = 1e-55, Method: Composition-based stats.
Identities = 78/374 (21%), Positives = 131/374 (35%), Gaps = 70/374 (19%)
Query 515 VLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTL 574
L+G + P + + + L F + R + + +N I+ R
Sbjct 501 TLKGKSKKVPMIPIVASVAGVFALLVILAIFFVVRRKNGESNKGTNPSIITKER------ 554
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
++++ V + LG+G VY G L
Sbjct 555 ---RITYPEVLKMTNNFERVLGKGGFGTVYHGNL-------------------------- 585
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
++ +V +K+L S F L+ +V H +L + G C G ++ EY+ +G
Sbjct 586 EDTQVAVKMLSHSSAQGYKEFKAEVELLLRVHHRNLVGLVGYCDDGDNLALIYEYMANGD 645
Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAE 749
L + +RG + W +M +A + A L YL N +VH +V NILL A
Sbjct 646 LKENMSGKRGGNVLTWENRMQIAVEAAQGLEYLHNGCTPPMVHRDVKTTNILLNERYGA- 704
Query 750 GTSPFIKLSDPGVGLG-ALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
KL+D G+ + E V +L PE N LS D + FG
Sbjct 705 ------KLADFGLSRSFPVDGESHVSTVVAGTPGYLDPEYYRT--NWLSEKSDVYSFGVV 756
Query 804 LLEICFDGEAPLQSR---SPSEKEHFYQRQHRLPEPSCPQL------------ATLTSQC 848
LLEI + ++R +E + + P+L L C
Sbjct 757 LLEIVTNQPVTDKTRERTHINEWVGSMLTKGDIKSILDPKLMGDYDTNGAWKIVELALAC 816
Query 849 LTYEPTQRPSFRTI 862
+ +RP+ +
Sbjct 817 VNPSSNRRPTMAHV 830
>sp|Q5E9Y0|CDK2_BOVIN Cyclin-dependent kinase 2 OS=Bos taurus
OX=9913 GN=CDK2 PE=2 SV=1
Length=298
Score = 223 bits (569), Expect = 2e-64, Method: Composition-based stats.
Identities = 69/289 (24%), Positives = 122/289 (42%), Gaps = 30/289 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+
Sbjct 1 MENFQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICE 1009
L H +I+K E L LV E++ L+ ++ I L + + Q+ +
Sbjct 57 ELNHPNIVKLLDVI--HTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQ 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
G+A+ H+ +HRDL +N+L++ D +K+ DFGLA+A R +++ A
Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINADGSIKLADFGLARAFGVP---VRTYTHEVVTLWYRA 170
Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL- 1127
PE L K+Y A D+WS G E++T ++ +L I + T +
Sbjct 171 PEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPG-DSEIDQLFRIFRTLGTPDEVVWPG 229
Query 1128 --LERGERLPRPDKCPCEV-----------YHLMKNCWETEASFRPTFE 1163
+ P + L+ + + R + +
Sbjct 230 VTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAK 278
Score = 171 bits (432), Expect = 6e-46, Method: Composition-based stats.
Identities = 47/266 (18%), Positives = 95/266 (36%), Gaps = 40/266 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
+ ++ +G+GT VY+ + ++ G V LK
Sbjct 1 MENFQKVEKIGEGTYGVVYKAKNKLTGE------------------------VVALKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
LD + SL+ +++H ++ + V + +V E++ H L ++
Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-HQDLKKFMDASA 95
Query 704 -GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+P+ QL L++ + ++H ++ +N+L+ G IKL+D G+
Sbjct 96 LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINADG-------SIKLADFGL 148
Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + + APE L G STA+D W G E+
Sbjct 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKY-YSTAVDIWSLGCIFAEMVTRRALFPGDS 207
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ E P + ++
Sbjct 208 EIDQLFRIFRTLGTPDEVVWPGVTSM 233
>sp|Q6H7U5|CIPKQ_ORYSJ CBL-interacting protein kinase 26 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK26 PE=2 SV=1
Length=493
Score = 230 bits (586), Expect = 2e-64, Method: Composition-based stats.
Identities = 60/275 (22%), Positives = 112/275 (41%), Gaps = 26/275 (9%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDIL 951
+ R LG+G+F KV N +G+ VA+K + + + K+EI I+
Sbjct 9 MDRYEIGRQLGQGNFAKVYY----ARNLTSGQAVAIKMIDKEKVTRVGLMVQIKREISIM 64
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011
R + H +I++ + + + V+EY G L + + + Q+ G+
Sbjct 65 RLVKHPNILQLFEVMASKSK--IYFVLEYAKGGELFKKISKGKFSEDVARRYFHQLISGI 122
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
Y H++ HRDL N+LLD + +K+ DFGL+ A+ E + + + APE
Sbjct 123 DYCHSRGVYHRDLKPENLLLDENESLKVSDFGLS-ALSESKRHDGLLHTTCGTPAYVAPE 181
Query 1072 CLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
L + +D+WS GV L+ L++ ++ + + +
Sbjct 182 VLSRRGYDGAKADIWSCGVILFVLVSGYLPFHDT---------------NLIEMYRKIAK 226
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
E P E+ L+ + + S R + +
Sbjct 227 AE-YKCPRSFSAELKDLLYKILDPDPSTRISIPKI 260
Score = 187 bits (476), Expect = 9e-50, Method: Composition-based stats.
Identities = 55/296 (19%), Positives = 95/296 (32%), Gaps = 45/296 (15%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
+ LGQG VY R G V +K
Sbjct 6 TILMDRYEIGRQLGQGNFAKVYYARNLTSGQ------------------------AVAIK 41
Query 643 VLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
++D + + + S+M V H ++ + V + V EY + G L +
Sbjct 42 MIDKEKVTRVGLMVQIKREISIMRLVKHPNILQLFEVMASKSKIYFVLEYAKGGELFKKI 101
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+G QL S + Y ++ + H ++ N+LL + +K+SD
Sbjct 102 --SKGKFSEDVARRYFHQLISGIDYCHSRGVYHRDLKPENLLLDE-------NESLKVSD 152
Query 760 PGVGLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ + S+ ++APE L D W G L + G
Sbjct 153 FGLSALSESKRHDGLLHTTCGTPAYVAPEVLSRRGYD-GAKADIWSCGVIL-FVLVSGYL 210
Query 814 PLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
P + E + +++ P +L L + L +P+ R S I R
Sbjct 211 PFHDTNLIEMYRKIAKAEYKCPRSFSAELKDLLYKILDPDPSTRISIPKIKRSAWY 266
>sp|C0LGG3|Y5182_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g51820 OS=Arabidopsis thaliana OX=3702
GN=At1g51820 PE=1 SV=1
Length=885
Score = 239 bits (610), Expect = 3e-64, Method: Composition-based stats.
Identities = 65/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (6%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
+ + R LG+G FG V + T E VAVK L Q
Sbjct 565 NRRFSYSQVVIMTNNFQRILGKGGFGMVYHGFVNGT-----EQVAVKILSHSSS-QGYKQ 618
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQ 999
+K E+++L ++H++++ G C++ +L L+ EY+ G L++++ R +
Sbjct 619 FKAEVELLLRVHHKNLVGLVGYCDEGD--NLALIYEYMANGDLKEHMSGTRNRFILNWGT 676
Query 1000 LLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
L + +G+ YLH +HRD+ N+LL+ K+ DFGL+++ E +
Sbjct 677 RLKIVIESAQGLEYLHNGCKPPMVHRDVKTTNILLNEHFEAKLADFGLSRSFLIEGETHV 736
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
+P + PE + SDV+SFG+ L E++T+ K +
Sbjct 737 STVVAGTP-GYLDPEYHRTNWLTEKSDVYSFGILLLEIITNRHVIDQSREK-PHIGEWVG 794
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+T + +++ + L +C ++ RPT ++ L
Sbjct 795 VMLTKGDIQSIMDPSLNEDYDSGSVWKAVELAMSCLNHSSARRPTMSQVVIELNE 849
Score = 211 bits (536), Expect = 6e-55, Method: Composition-based stats.
Identities = 74/337 (22%), Positives = 115/337 (34%), Gaps = 61/337 (18%)
Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
P + S+ + R + + T N + S+ +V LG+G VY G +
Sbjct 542 PPSYMQASDGRLPRSSEPAIVTKN-RRFSYSQVVIMTNNFQRILGKGGFGMVYHGFVNGT 600
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
+V +K+L S F L+ +V H +L
Sbjct 601 E-------------------------QVAVKILSHSSSQGYKQFKAEVELLLRVHHKNLV 635
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN-- 727
+ G C G ++ EY+ +G L + R + W ++ + + A L YL N
Sbjct 636 GLVGYCDEGDNLALIYEYMANGDLKEHMSGTRNRFILNWGTRLKIVIESAQGLEYLHNGC 695
Query 728 -KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL-SREERV-----ERIPWLA 780
+VH +V NILL A KL+D G+ L E V +L
Sbjct 696 KPPMVHRDVKTTNILLNEHFEA-------KLADFGLSRSFLIEGETHVSTVVAGTPGYLD 748
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR---SPSEKEHFYQRQHRLPEPS 837
PE N L+ D + FG LLEI + QSR E + +
Sbjct 749 PEY--HRTNWLTEKSDVYSFGILLLEIITNRHVIDQSREKPHIGEWVGVMLTKGDIQSIM 806
Query 838 CPQL------------ATLTSQCLTYEPTQRPSFRTI 862
P L L CL + +RP+ +
Sbjct 807 DPSLNEDYDSGSVWKAVELAMSCLNHSSARRPTMSQV 843
>sp|A4K2Q5|STK4_OTOGA Serine/threonine-protein kinase 4 OS=Otolemur
garnettii OX=30611 GN=STK4 PE=3 SV=1
Length=487
Score = 230 bits (586), Expect = 3e-64, Method: Composition-based stats.
Identities = 67/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K
Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
++ C R T L+
Sbjct 250 WSDNFTDFVRQCLVKSPDQRATATQLLQ 277
Score = 202 bits (515), Expect = 6e-55, Method: Composition-based stats.
Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L + S + ++ L LG+G+ +VY+ + G
Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K + + S+M Q H+ +G + + +V EY G +
Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + Q L YL +H ++ NILL G
Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163
Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D GV R + W+APE + + D W G T +E+ +G
Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220
Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P P R PE QCL P QR + +L+
Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVRQCLVKSPDQRATATQLLQHPF 280
>sp|O22833|LRK54_ARATH L-type lectin-domain containing receptor
kinase V.4 OS=Arabidopsis thaliana OX=3702 GN=LECRK54 PE=2
SV=1
Length=658
Score = 234 bits (597), Expect = 3e-64, Method: Composition-based stats.
Identities = 73/317 (23%), Positives = 130/317 (41%), Gaps = 17/317 (5%)
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920
+I + + + + K + LG+G FG+V + T
Sbjct 298 SIFFYRRHKKVKEVLEEWEIQCGPHRFAYKELFKATKGFKQLLGKGGFGQV----FKGTL 353
Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
G+ +AVK + D Q + EI + L H+++++ +G C + E L LV ++
Sbjct 354 PGSDAEIAVKRISHD-SKQGMQEFLAEISTIGRLRHQNLVRLQGYCRYKEE--LYLVYDF 410
Query 981 VPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQHY---IHRDLAARNVLLDN 1033
+P GSL YL + + Q + I + YLH + IHRD+ NVL+D+
Sbjct 411 MPNGSLDKYLYHRANQEQLTWNQRFKIIKDIASALCYLHHEWVQVVIHRDIKPANVLIDH 470
Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
++GDFGLAK +G++ R G ++ APE ++ + +DV++FG+ + E
Sbjct 471 QMNARLGDFGLAKLYDQGYDPQTSRVAG--TFWYIAPELIRSGRATTGTDVYAFGLFMLE 528
Query 1094 LLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152
+ + + + L + E + G R + V L C
Sbjct 529 VSCGRRLIERRTASDEVVLAEWTLKCWENGDILEAVNDGIRHEDNREQLELVLKLGVLCS 588
Query 1153 ETEASFRPTFENLIPIL 1169
+ RP ++ IL
Sbjct 589 HQAVAIRPDMSKVVQIL 605
Score = 207 bits (527), Expect = 5e-55, Method: Composition-based stats.
Identities = 52/284 (18%), Positives = 99/284 (35%), Gaps = 64/284 (23%)
Query 582 HRVDQKEITQLSH-----LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
HR KE+ + + LG+G V++G L G +
Sbjct 322 HRFAYKELFKATKGFKQLLGKGGFGQVFKGTL------------------------PGSD 357
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+ +K + F S + ++ H +L + G C E +V +++ +G LD
Sbjct 358 AEIAVKRISHDSKQGMQEFLAEISTIGRLRHQNLVRLQGYCRYKEELYLVYDFMPNGSLD 417
Query 697 VWL--RRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT 751
+L R + + + + + +ASAL YL + + ++H ++ N+L+
Sbjct 418 KYLYHRANQEQLTWNQRFKIIKDIASALCYLHHEWVQVVIHRDIKPANVLIDHQ------ 471
Query 752 SPFIKLSDPGVGLGA-----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+L D G+ ++APE + G +T D + FG +LE
Sbjct 472 -MNARLGDFGLAKLYDQGYDPQTSRVAGTFWYIAPELIRSGRA--TTGTDVYAFGLFMLE 528
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLT 850
+ + + E LA T +C
Sbjct 529 VSCGRRLIERRTASDEVV----------------LAEWTLKCWE 556
>sp|Q9LK35|THE1_ARATH Receptor-like protein kinase THESEUS 1 OS=Arabidopsis
thaliana OX=3702 GN=THE1 PE=1 SV=1
Length=855
Score = 238 bits (608), Expect = 3e-64, Method: Composition-based stats.
Identities = 75/300 (25%), Positives = 122/300 (41%), Gaps = 20/300 (7%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
+ + LG G FG+V + G VAVK Q
Sbjct 493 HLGRCFMFQEIMDATNKFDESSLLGVGGFGRVYKGTLE-----DGTKVAVKRGNPR-SEQ 546
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIG 996
+ ++ EI++L L H H++ G C+++ E + LV EY+ G LR +L +
Sbjct 547 GMAEFRTEIEMLSKLRHRHLVSLIGYCDERSE--MILVYEYMANGPLRSHLYGADLPPLS 604
Query 997 LAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
Q L G+ YLH +Q IHRD+ N+LLD + + K+ DFGL+K P +
Sbjct 605 WKQRLEICIGAARGLHYLHTGASQSIIHRDVKTTNILLDENLVAKVADFGLSKTGPSLDQ 664
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
+ V + PE + + SDV+SFGV L E+L C P E +
Sbjct 665 TH-VSTAVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLMEVL--CCRPALNPVLPREQVN 721
Query 1114 IAQGQMTVLR---LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
IA+ M + L ++++ + + C RP+ +++ L+
Sbjct 722 IAEWAMAWQKKGLLDQIMDSNLTGKVNPASLKKFGETAEKCLAEYGVDRPSMGDVLWNLE 781
Score = 226 bits (577), Expect = 3e-60, Method: Composition-based stats.
Identities = 66/348 (19%), Positives = 116/348 (33%), Gaps = 61/348 (18%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ + S LG G VY+G L +V +K
Sbjct 506 ATNKFDESSLLGVGGFGRVYKGTLEDG-------------------------TKVAVKRG 540
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER- 703
+P F ++S++ H HL + G C E I+V EY+ +GPL L
Sbjct 541 NPRSEQGMAEFRTEIEMLSKLRHRHLVSLIGYCDERSEMILVYEYMANGPLRSHLYGADL 600
Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ ++ + A L YL +++++H +V NILL + K++D
Sbjct 601 PPLSWKQRLEICIGAARGLHYLHTGASQSIIHRDVKTTNILLDE-------NLVAKVADF 653
Query 761 GVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA- 813
G+ S ++ +L PE L+ D + FG L+E+ A
Sbjct 654 GLSKTGPSLDQTHVSTAVKGSFGYLDPEYFR--RQQLTEKSDVYSFGVVLMEVLCCRPAL 711
Query 814 ----PLQSRSPSEKEHFYQRQHRLPEPSCPQLA------------TLTSQCLTYEPTQRP 857
P + + +E +Q++ L + L +CL RP
Sbjct 712 NPVLPREQVNIAEWAMAWQKKGLLDQIMDSNLTGKVNPASLKKFGETAEKCLAEYGVDRP 771
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
S +L +L + PD +++ + D
Sbjct 772 SMGDVLWNLEYALQLEETSSALMEPDDNSTNHIPGIPMAPMEPFDNSM 819
>sp|A4K2P5|STK4_COLGU Serine/threonine-protein kinase 4 OS=Colobus
guereza OX=33548 GN=STK4 PE=3 SV=1
Length=487
Score = 229 bits (585), Expect = 3e-64, Method: Composition-based stats.
Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K
Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLQSTLKGLEYLHFMRK 145
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+K C R T L+
Sbjct 250 WSDNFTDFVKQCLVKSPEQRATATQLLQ 277
Score = 201 bits (512), Expect = 2e-54, Method: Composition-based stats.
Identities = 60/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L + S + ++ L LG+G+ +VY+ + G
Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K + + S+M Q H+ +G + + +V EY G +
Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + V Q L YL +H ++ NILL G
Sbjct 111 SDIIRLRNKTLTEDEIATVLQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163
Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D GV R + W+APE + + D W G T +E+ +G
Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220
Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P P R PE QCL P QR + +L+
Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPF 280
>sp|Q0JI49|CIPKB_ORYSJ CBL-interacting protein kinase 11 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK11 PE=2 SV=1
Length=502
Score = 230 bits (586), Expect = 4e-64, Method: Composition-based stats.
Identities = 62/269 (23%), Positives = 109/269 (41%), Gaps = 31/269 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960
LG+G F KV N TG+ VA+K + D + K+EI I+R + H +++
Sbjct 18 LGQGTFAKVYY----ARNLTTGQAVAIKMINKDKVMKVGLMEQIKREISIMRLVKHPNVL 73
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ + + + V+EY G L + + + + + Q+ + Y H++
Sbjct 74 QLFEVMASKSK--IYFVLEYAKGGELFNKIAKEGKLSEDSARRYFHQLINAVDYCHSRGV 131
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
HRDL N+LLD + +K+ DFGL+ + + +P + APE L +
Sbjct 132 YHRDLKPENLLLDENENLKVSDFGLSALAESKRQDGLLHTTCGTPA-YVAPEVLSRKGYD 190
Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP--R 1136
+DVWS GV L+ L+ P L E+ + R
Sbjct 191 GAKADVWSCGVILFVLVAGYLPFHDP------------------NLIEMYRKICRADFRC 232
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P E+ L+ +++ S R + +
Sbjct 233 PRYFSAELKDLIHKILDSDPSTRISIPRI 261
Score = 186 bits (473), Expect = 3e-49, Method: Composition-based stats.
Identities = 58/287 (20%), Positives = 94/287 (33%), Gaps = 44/287 (15%)
Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH-- 649
LGQGT VY R G V +K+++
Sbjct 15 GKQLGQGTFAKVYYARNLTTGQ------------------------AVAIKMINKDKVMK 50
Query 650 -DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ S+M V H ++ + V + V EY + G L + +E G +
Sbjct 51 VGLMEQIKREISIMRLVKHPNVLQLFEVMASKSKIYFVLEYAKGGELFNKIAKE-GKLSE 109
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
QL +A+ Y ++ + H ++ N+LL + +K+SD G+ A S
Sbjct 110 DSARRYFHQLINAVDYCHSRGVYHRDLKPENLLLDE-------NENLKVSDFGLSALAES 162
Query 769 R------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ ++APE L D W G L + G P + E
Sbjct 163 KRQDGLLHTTCGTPAYVAPEVLSRKGYD-GAKADVWSCGVIL-FVLVAGYLPFHDPNLIE 220
Query 823 K-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ R P +L L + L +P+ R S I R
Sbjct 221 MYRKICRADFRCPRYFSAELKDLIHKILDSDPSTRISIPRIKRSTWY 267
>sp|A4K2S1|STK4_LEMCA Serine/threonine-protein kinase 4 OS=Lemur
catta OX=9447 GN=STK4 PE=3 SV=1
Length=487
Score = 229 bits (585), Expect = 4e-64, Method: Composition-based stats.
Identities = 67/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K
Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
++ C R T L+
Sbjct 250 WSDNFMDFVRQCLVKSPDQRATATQLLQ 277
Score = 202 bits (515), Expect = 8e-55, Method: Composition-based stats.
Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L + S + ++ L LG+G+ +VY+ + G
Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K + + S+M Q H+ +G + + +V EY G +
Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + Q L YL +H ++ NILL G
Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163
Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D GV R + W+APE + + D W G T +E+ +G
Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220
Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P P R PE QCL P QR + +L+
Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFMDFVRQCLVKSPDQRATATQLLQHPF 280
>sp|Q39008|M3K1_ARATH Mitogen-activated protein kinase kinase
kinase 1 OS=Arabidopsis thaliana OX=3702 GN=MEKK1 PE=1 SV=2
Length=608
Score = 233 bits (593), Expect = 4e-64, Method: Composition-based stats.
Identities = 76/278 (27%), Positives = 122/278 (44%), Gaps = 34/278 (12%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQ---EIDILR 952
+K + LG G FG V G G+ AVK + D G Q + +Q EI +L
Sbjct 333 WQKGQLLGRGSFGSVYEGI-----SGDGDFFAVKEVSLLDQGSQAQECIQQLEGEIKLLS 387
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
L H++I++Y+G +D +L + +E V GSL R+ + + + L+ +QI +G+
Sbjct 388 QLQHQNIVRYRGTAKDGS--NLYIFLELVTQGSLLKLYQRYQLRDSVVSLYTRQILDGLK 445
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
YLH + +IHRD+ N+L+D + VK+ DFGLAK + FW APE
Sbjct 446 YLHDKGFIHRDIKCANILVDANGAVKLADFGLAKVSKFNDI-----KSCKGTPFWMAPEV 500
Query 1073 LKEY---KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
+ + +D+WS G T+ E+ T I + ++ +
Sbjct 501 INRKDSDGYGSPADIWSLGCTVLEMCTG---------------QIPYSDLEPVQALFRIG 545
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
RG PD + + C + RPT L+
Sbjct 546 RGTLPEVPDTLSLDARLFILKCLKVNPEERPTAAELLN 583
Score = 194 bits (493), Expect = 5e-51, Method: Composition-based stats.
Identities = 55/282 (20%), Positives = 100/282 (35%), Gaps = 35/282 (12%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ LG+G+ +VYEG +E + D+ +
Sbjct 335 KGQLLGRGSFGSVYEGISGDGDFFAVKEVSLLDQGSQA--------------------QE 374
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
L+SQ+ H ++ G G + E V G L +R + +
Sbjct 375 CIQQLEGEIKLLSQLQHQNIVRYRGTAKDGSNLYIFLELVTQGSLLKL--YQRYQLRDSV 432
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA--LS 768
+ +Q+ L YL +K +H ++ NIL+ + +KL+D G+ +
Sbjct 433 VSLYTRQILDGLKYLHDKGFIHRDIKCANILVD-------ANGAVKLADFGLAKVSKFND 485
Query 769 REERVERIPWLAPECL-PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
+ W+APE + ++ + D W G T+LE+C G+ P P +
Sbjct 486 IKSCKGTPFWMAPEVINRKDSDGYGSPADIWSLGCTVLEMC-TGQIPYSDLEPVQALFRI 544
Query 828 QRQ--HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
R +P+ +CL P +RP+ +L
Sbjct 545 GRGTLPEVPDTLSLDARLFILKCLKVNPEERPTAAELLNHPF 586
>sp|Q54RZ7|Y1199_DICDI Probable serine/threonine-protein kinase
DDB_G0282895 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0282895
PE=3 SV=1
Length=1634
Score = 243 bits (620), Expect = 4e-64, Method: Composition-based stats.
Identities = 72/288 (25%), Positives = 131/288 (45%), Gaps = 26/288 (9%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
A T + L+ ++ LGEG +V + G+ VAVK +
Sbjct 1365 QAFAHTQIEESELQILQFLGEGALAEVHKGIWK------GKEVAVKIFNEGSFSFRLEDF 1418
Query 945 KQEIDILRTLYHEHIIKYKGCCE--DQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLL 1001
+E+ IL + H +++K KG C + + +V E + G+L + + ++ + L ++
Sbjct 1419 LKEVAILGLISHPNLLKLKGACIAPRSHKSTFMIVTELMHKGTLLEVINKNKPLSLEDII 1478
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
+A + +G+AYLH+ +IHRD+ A N+L+D + K+GDFGL++ +
Sbjct 1479 KYALSVAQGLAYLHSVDFIHRDIKAANILVDKNNNAKVGDFGLSRVIDNNFN----MTAV 1534
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
W +PECL + ASDV+S+G+ L+EL T P + ++ +A+
Sbjct 1535 AGTPKWESPECLMGEAYTSASDVYSYGMMLFELATG----DEPFLEIQSIVELAR----- 1585
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ ++ + P + L+K+C RPT +I L
Sbjct 1586 ----SVCDKKLKPKISSSVPNFISSLIKDCLHNSPKKRPTMNQIIQKL 1629
Score = 201 bits (512), Expect = 4e-51, Method: Composition-based stats.
Identities = 58/297 (20%), Positives = 119/297 (40%), Gaps = 47/297 (16%)
Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
+ ++++ E+ L LG+G V++G + +
Sbjct 1367 FAHTQIEESELQILQFLGEGALAEVHKGIWKGK--------------------------E 1400
Query 639 VVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCV----RGPENIMVTEYVEHG 693
V +K+ + L F + +++ +SH +L + G C+ ++VTE + G
Sbjct 1401 VAVKIFNEGSFSFRLEDFLKEVAILGLISHPNLLKLKGACIAPRSHKSTFMIVTELMHKG 1460
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L + + + + + + A +A L+YL + + +H ++ NIL+ + +
Sbjct 1461 TLLEVINKNK-PLSLEDIIKYALSVAQGLAYLHSVDFIHRDIKAANILVDK-------NN 1512
Query 754 FIKLSDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K+ D G+ + W +PECL G A ++A D + +G L E+
Sbjct 1513 NAKVGDFGLSRVIDNNFNMTAVAGTPKWESPECLMGEA--YTSASDVYSYGMMLFELATG 1570
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCP---QLATLTSQCLTYEPTQRPSFRTILR 864
E L+ +S E + P+ S +++L CL P +RP+ I++
Sbjct 1571 DEPFLEIQSIVELARSVCDKKLKPKISSSVPNFISSLIKDCLHNSPKKRPTMNQIIQ 1627
>sp|Q6R2J8|SRF8_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 8 OS=Arabidopsis
thaliana OX=3702 GN=SRF8 PE=1 SV=1
Length=703
Score = 235 bits (599), Expect = 4e-64, Method: Composition-based stats.
Identities = 71/299 (24%), Positives = 125/299 (42%), Gaps = 25/299 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG G+V + G+++A+K + A Q + + + + L H +I+
Sbjct 401 IGEGSLGRVYRAEF-----PNGKIMAIKKIDNAALSLQEEDNFLEAVSNMSRLRHPNIVP 455
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHA 1016
G C + G++ LV EYV G+L D L + ++ + A + + YLH
Sbjct 456 LAGYCTEHGQR--LLVYEYVGNGNLDDTLHTNDDRSMNLTWNARVKVALGTAKALEYLHE 513
Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+HR+ + N+LLD + + D GLA P +V + APE
Sbjct 514 VCLPSIVHRNFKSANILLDEELNPHLSDSGLAALTPNTER--QVSTQVVGSFGYSAPEFA 571
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQM-TVLRLTELLERG 1131
+ SDV++FGV + ELLT S T+ L+ A Q+ + L+++++
Sbjct 572 LSGIYTVKSDVYTFGVVMLELLTGRKPLDSSRTRAEQSLVRWATPQLHDIDALSKMVDPS 631
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE-----KYQGQAPSVFS 1185
P K ++ C + E FRP ++ L + + K + + FS
Sbjct 632 LNGMYPAKSLSRFADIIALCIQPEPEFRPPMSEVVQQLVRLVQRASVVKRRSSDDTGFS 690
Score = 197 bits (501), Expect = 2e-51, Method: Composition-based stats.
Identities = 74/357 (21%), Positives = 127/357 (36%), Gaps = 65/357 (18%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
SP T + +S +V +Q + +G+G+ VY
Sbjct 376 SPITASQYTVSSLQVATNSFSQENIIGEGSLGRVYRA----------------------- 412
Query 630 GRDRGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
+ + +K +D + + F E S MS++ H ++ + G C + ++V
Sbjct 413 --EFPNGKIMAIKKIDNAALSLQEEDNFLEAVSNMSRLRHPNIVPLAGYCTEHGQRLLVY 470
Query 688 EYVEHGPLDVWLRRERG---HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNIL 741
EYV +G LD L ++ ++ VA A AL YL ++VH N NIL
Sbjct 471 EYVGNGNLDDTLHTNDDRSMNLTWNARVKVALGTAKALEYLHEVCLPSIVHRNFKSANIL 530
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMD 796
L LSD G+ + E +V + APE G + D
Sbjct 531 LDEELNPH-------LSDSGLAALTPNTERQVSTQVVGSFGYSAPEFALSGI--YTVKSD 581
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS------------------C 838
+ FG +LE+ + SR+ +E+ +L +
Sbjct 582 VYTFGVVMLELLTGRKPLDSSRTRAEQSLVRWATPQLHDIDALSKMVDPSLNGMYPAKSL 641
Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895
+ A + + C+ EP RP +++ L RL + D+ S T H+
Sbjct 642 SRFADIIALCIQPEPEFRPPMSEVVQQLVRLVQRASVVKRRSSDDTGFSYRTPEHEH 698
>sp|Q55GG4|Y9847_DICDI Probable serine/threonine-protein kinase
DDB_G0267686 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0267686
PE=3 SV=1
Length=2230
Score = 243 bits (621), Expect = 4e-64, Method: Composition-based stats.
Identities = 67/301 (22%), Positives = 125/301 (42%), Gaps = 24/301 (8%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
+ + + LGEG KV + + VAVK L+++ Q +
Sbjct 1937 MNFNNWAIDGEEIVFLNKLGEGTSAKVYRATWR------NQEVAVKVLRSEPESQKLLDF 1990
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLF 1003
+E++I+ +L H++ + G D + ++MEY +L + + + + F
Sbjct 1991 LKELEIMSSLRSPHVVYFYGMVLDP---KICMIMEYCSNQTLYHLMHLQMNFTWDWVFKF 2047
Query 1004 AQQICEGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
A ++ G+ LH+ +HRDL + N+L+ ++ +K+ DFGL++ R
Sbjct 2048 AIEMVRGVNCLHSWKPVIVHRDLKSLNLLVSDNWTIKVADFGLSRFATAKSASNRTTR-- 2105
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC--DSSQSPPTKFLELIGIAQGQM 1119
+ APE D++S G+ L+EL C + P ++F + Q
Sbjct 2106 -GTFAYCAPEVF-YGIHTTKGDIFSIGIILWELAVRCIKSKYEKPFSEFKHI------QY 2157
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L + + R P CP +L+ NCWE+ RP+ ++ L + +KY
Sbjct 2158 DFQILVQTSKFNLRPTIPQNCPEAFSNLISNCWESSPDNRPSCPEILDSLLDMEKKYTEN 2217
Query 1180 A 1180
Sbjct 2218 K 2218
Score = 193 bits (490), Expect = 2e-48, Method: Composition-based stats.
Identities = 64/323 (20%), Positives = 114/323 (35%), Gaps = 57/323 (18%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
T L + +D +EI L+ LG+GT VY R +
Sbjct 1933 TKVLMNFNNWAIDGEEIVFLNKLGEGTSAKVYRATWRNQ--------------------- 1971
Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
V +KVL L F + +MS + H+ + +G+ + P+ M+ EY
Sbjct 1972 -----EVAVKVLRSEPESQKLLDFLKELEIMSSLRSPHVVYFYGMVLD-PKICMIMEYCS 2025
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAE 749
+ L L + + W A ++ ++ L + +VH ++ N+L++
Sbjct 2026 NQTLY-HLMHLQMNFTWDWVFKFAIEMVRGVNCLHSWKPVIVHRDLKSLNLLVS------ 2078
Query 750 GTSPFIKLSDPGVGLGALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ IK++D G+ A ++ + APE G +T D + G L
Sbjct 2079 -DNWTIKVADFGLSRFATAKSASNRTTRGTFAYCAPEVFYG---IHTTKGDIFSIGIILW 2134
Query 806 EICFDGEAPLQSRSPSEKEHFYQR------------QHRLPEPSCPQLATLTSQCLTYEP 853
E+ + SE +H + +P+ + L S C P
Sbjct 2135 ELAVRCIKSKYEKPFSEFKHIQYDFQILVQTSKFNLRPTIPQNCPEAFSNLISNCWESSP 2194
Query 854 TQRPSFRTILRDLTRLQPHNLAD 876
RPS IL L ++ +
Sbjct 2195 DNRPSCPEILDSLLDMEKKYTEN 2217
>sp|Q852Q1|OSK4_ORYSJ Serine/threonine protein kinase OSK4 OS=Oryza
sativa subsp. japonica OX=39947 GN=OSK4 PE=1 SV=1
Length=509
Score = 230 bits (586), Expect = 4e-64, Method: Composition-based stats.
Identities = 74/280 (26%), Positives = 109/280 (39%), Gaps = 30/280 (11%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQE 947
+ R LG G FGKV + + TG VA+K L + K+E
Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKRE 65
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006
I ILR H HII+ + + +VMEY G L DY+ + + + QQ
Sbjct 66 IKILRLFIHPHIIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQ 123
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I G+ Y H +HRDL N+LLD+ VK+ DFGL+ + +G + ++ SP
Sbjct 124 IISGVEYCHRNMVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDG---HFLKTSCGSPN- 179
Query 1067 WYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+ APE + + DVWS GV LY LL + L
Sbjct 180 YAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE---------------NIPNLF 224
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ ++ G P L+ + R T +
Sbjct 225 KKIKGGI-YTLPSHLSALARDLIPRMLVVDPMKRITIREI 263
Score = 182 bits (461), Expect = 1e-47, Method: Composition-based stats.
Identities = 52/332 (16%), Positives = 100/332 (30%), Gaps = 39/332 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
H K LG G+ V ++ G RV +
Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKIAEHKLTGH------------------------RVAI 45
Query 642 KVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
K+L+ + ++ ++ H H+ ++ V + +V EY + G L +
Sbjct 46 KILNRRQMRNMEMEEKAKREIKILRLFIHPHIIRLYEVIYTPTDIYVVMEYCKFGELFDY 105
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ E+G + + QQ+ S + Y +VH ++ N+LL +KL+
Sbjct 106 I-VEKGRLQEDEARRIFQQIISGVEYCHRNMVVHRDLKPENLLLDSK-------YNVKLA 157
Query 759 DPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
D G+ + + APE + G + +D W G L +
Sbjct 158 DFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYALLCGTLPFD 216
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
P+ + + LP L + L +P +R + R I
Sbjct 217 DENIPNLFKKIKGGIYTLPSHLSALARDLIPRMLVVDPMKRITIREIREHQWFQIRLPRY 276
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
+ + + + H
Sbjct 277 LAVPPPDTAQQAKMIDEDTLQDVVNLGYEKDH 308
>sp|B8BBT7|OSK4_ORYSI Serine/threonine protein kinase OSK4 OS=Oryza
sativa subsp. indica OX=39946 GN=OSK4 PE=3 SV=1
Length=509
Score = 230 bits (586), Expect = 4e-64, Method: Composition-based stats.
Identities = 74/280 (26%), Positives = 109/280 (39%), Gaps = 30/280 (11%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQE 947
+ R LG G FGKV + + TG VA+K L + K+E
Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKRE 65
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006
I ILR H HII+ + + +VMEY G L DY+ + + + QQ
Sbjct 66 IKILRLFIHPHIIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQ 123
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I G+ Y H +HRDL N+LLD+ VK+ DFGL+ + +G + ++ SP
Sbjct 124 IISGVEYCHRNMVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDG---HFLKTSCGSPN- 179
Query 1067 WYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+ APE + + DVWS GV LY LL + L
Sbjct 180 YAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE---------------NIPNLF 224
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ ++ G P L+ + R T +
Sbjct 225 KKIKGGI-YTLPSHLSALARDLIPRMLVVDPMKRITIREI 263
Score = 182 bits (461), Expect = 1e-47, Method: Composition-based stats.
Identities = 52/332 (16%), Positives = 100/332 (30%), Gaps = 39/332 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
H K LG G+ V ++ G RV +
Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKIAEHKLTGH------------------------RVAI 45
Query 642 KVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
K+L+ + ++ ++ H H+ ++ V + +V EY + G L +
Sbjct 46 KILNRRQMRNMEMEEKAKREIKILRLFIHPHIIRLYEVIYTPTDIYVVMEYCKFGELFDY 105
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ E+G + + QQ+ S + Y +VH ++ N+LL +KL+
Sbjct 106 I-VEKGRLQEDEARRIFQQIISGVEYCHRNMVVHRDLKPENLLLDSK-------YNVKLA 157
Query 759 DPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
D G+ + + APE + G + +D W G L +
Sbjct 158 DFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYALLCGTLPFD 216
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
P+ + + LP L + L +P +R + R I
Sbjct 217 DENIPNLFKKIKGGIYTLPSHLSALARDLIPRMLVVDPMKRITIREIREHQWFQIRLPRY 276
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
+ + + + H
Sbjct 277 LAVPPPDTAQQAKMIDEDTLQDVVNLGYEKDH 308
>sp|Q9FIJ6|ACCR4_ARATH Serine/threonine-protein kinase-like protein
CCR4 OS=Arabidopsis thaliana OX=3702 GN=CCR4 PE=1 SV=1
Length=751
Score = 236 bits (602), Expect = 4e-64, Method: Composition-based stats.
Identities = 85/396 (21%), Positives = 145/396 (37%), Gaps = 42/396 (11%)
Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTS-----------QCLTYEPTQRPS 858
DGE P S+ + + +R C +L +C ++ +
Sbjct 344 DGEFPDTRAQNSKNKTWSRRNIAFLVVGCVGTFSLLLVISFLIFKSHCRCRVHDSGRLDD 403
Query 859 FRTILRDL-TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917
RTI + + + D LG G FG V
Sbjct 404 TRTIDIPKLEKRLCTLASLGNPGQLMEFSIDELALATDGFSVRFHLGIGSFGSVYQGVL- 462
Query 918 PTNDGTGEMVAVKA------------LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGC 965
G VA+K ++ + S + E++ + L H+++++ G
Sbjct 463 ----SDGRHVAIKRAELTNPTLSGTTMRHRRADKD-SAFVNELESMSRLNHKNLVRLLGF 517
Query 966 CEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHA---QHY 1019
ED E+ LV EY+ GSL D+L + L+ A G+ YLH
Sbjct 518 YEDTEER--ILVYEYMKNGSLADHLHNPQFDPLSWQTRLMIALDAARGIQYLHEFIVPPV 575
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ + N+LLD K+ DFGL++ P E + + + + PE K +
Sbjct 576 IHRDIKSSNILLDATWTAKVSDFGLSQMGPTEEDDVSHLSLHAAGTLGYIDPEYYKFQQL 635
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
SDV+SFGV L ELL+ + + L+ + + +L++ P P
Sbjct 636 TTKSDVYSFGVVLLELLSGHKAIHNNEDENPRNLVEYVVPYILLDEAHRILDQRIPPPTP 695
Query 1138 --DKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ V +L C + RP+ ++ L++
Sbjct 696 YEIEAVAHVGYLAAECLMPCSRKRPSMVEVVSKLES 731
Score = 204 bits (518), Expect = 3e-53, Method: Composition-based stats.
Identities = 64/339 (19%), Positives = 116/339 (34%), Gaps = 54/339 (16%)
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P L + + +P L + + + HLG G+ +VY+G L
Sbjct 410 PKLEKRLCTL-ASLGNPGQLMEFSIDELALATDGFSVRFHLGIGSFGSVYQGVLSDGRHV 468
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
+ ++ + + D AF MS+++H +L +
Sbjct 469 AIKRAELTNPTLSGT-------------TMRHRRADKDSAFVNELESMSRLNHKNLVRLL 515
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLEN---KNL 730
G E I+V EY+++G L L + + ++++A A + YL +
Sbjct 516 GFYEDTEERILVYEYMKNGSLADHLHNPQFDPLSWQTRLMIALDAARGIQYLHEFIVPPV 575
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV--------ERIPWLAPE 782
+H ++ NILL + K+SD G+ + E+ V + ++ PE
Sbjct 576 IHRDIKSSNILLD-------ATWTAKVSDFGLSQMGPTEEDDVSHLSLHAAGTLGYIDPE 628
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFD--------GEAPLQSRSPSEKEHFYQRQHRLP 834
L+T D + FG LLE+ E P HR+
Sbjct 629 YYK--FQQLTTKSDVYSFGVVLLELLSGHKAIHNNEDENPRNLVEYVVPYILLDEAHRIL 686
Query 835 EPSCP-----------QLATLTSQCLTYEPTQRPSFRTI 862
+ P + L ++CL +RPS +
Sbjct 687 DQRIPPPTPYEIEAVAHVGYLAAECLMPCSRKRPSMVEV 725
>sp|Q9LZM4|WAKLQ_ARATH Wall-associated receptor kinase-like 20
OS=Arabidopsis thaliana OX=3702 GN=WAKL20 PE=2 SV=1
Length=657
Score = 234 bits (596), Expect = 4e-64, Method: Composition-based stats.
Identities = 67/286 (23%), Positives = 123/286 (43%), Gaps = 24/286 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG+V + G + A+K K + + E+ IL + H +++
Sbjct 369 IGTGGFGEVFKAVLE-----DGTITAIKRAKLN-NTKGTDQILNEVRILCQVNHRSLVRL 422
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR------HSIGLAQLLLFAQQICEGMAYLHA 1016
GCC D + L+ E++P G+L ++L + + L A Q EG+AYLH+
Sbjct 423 LGCCVDL--ELPLLIYEFIPNGTLFEHLHGSSDRTWKPLTWRRRLQIAYQTAEGLAYLHS 480
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR---VREDGDSPVFWYAP 1070
HRD+ + N+LLD K+ DFGL++ V + + + P
Sbjct 481 AAQPPIYHRDVKSSNILLDEKLNAKVSDFGLSRLVDLTETANNESHIFTGAQGTLGYLDP 540
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E + ++ SDV+SFGV L E++T + + + + L+ M RLTE ++
Sbjct 541 EYYRNFQLTDKSDVYSFGVVLLEMVTSKKAIDFTREEEDVNLVMYINKMMDQERLTECID 600
Query 1130 RGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ + ++ +L C RP+ + + ++ +
Sbjct 601 PLLKKTANKIDMQTIQQLGNLASACLNERRQNRPSMKEVADEIEYI 646
Score = 209 bits (533), Expect = 8e-56, Method: Composition-based stats.
Identities = 63/351 (18%), Positives = 111/351 (32%), Gaps = 74/351 (21%)
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615
E ++ S R +++ ++ + +G G V++ L
Sbjct 333 KEREEMLSANSTGKSSRIFTGREITK---ATNNFSKDNLIGTGGFGEVFKAVLEDGTIT- 388
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675
+K ++ ++ QV+H L + G
Sbjct 389 ------------------------AIKRAKLNNTKGTDQILNEVRILCQVNHRSLVRLLG 424
Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRERGHV--PMAW--KMVVAQQLASALSYLEN---K 728
CV +++ E++ +G L L P+ W ++ +A Q A L+YL +
Sbjct 425 CCVDLELPLLIYEFIPNGTLFEHLHGSSDRTWKPLTWRRRLQIAYQTAEGLAYLHSAAQP 484
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV----------ERIPW 778
+ H +V NILL K+SD G+ E + +
Sbjct 485 PIYHRDVKSSNILLDEKL-------NAKVSDFGLSRLVDLTETANNESHIFTGAQGTLGY 537
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-----EHFYQRQHRL 833
L PE L+ D + FG LLE+ +A +R + + Q RL
Sbjct 538 LDPEYYRN--FQLTDKSDVYSFGVVLLEMVTSKKAIDFTREEEDVNLVMYINKMMDQERL 595
Query 834 PEPSCPQLAT---------------LTSQCLTYEPTQRPSFRTILRDLTRL 869
E P L L S CL RPS + + ++ +
Sbjct 596 TECIDPLLKKTANKIDMQTIQQLGNLASACLNERRQNRPSMKEVADEIEYI 646
>sp|Q54QQ1|PHG2_DICDI Serine/threonine-protein kinase phg2 OS=Dictyostelium
discoideum OX=44689 GN=phg2 PE=1 SV=1
Length=1387
Score = 242 bits (618), Expect = 5e-64, Method: Composition-based stats.
Identities = 69/289 (24%), Positives = 124/289 (43%), Gaps = 20/289 (7%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHE 957
I+ +G G + KV Y + VA+K ++ ++ + +K+E DIL T+
Sbjct 809 YIKRIGSGTYSKVYKGKYR------DKFVAIKTMRGSNMTTEQIESFKKECDILSTIQSP 862
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLH 1015
+I + G C + E L +V+EY G+L L + + ++ EG+ YLH
Sbjct 863 LLISFYGSCIE--ESQLSMVVEYCSKGTLHKVLNNPLLDFDWDKWFKWMTEVVEGVRYLH 920
Query 1016 AQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ + +HRDL N+L+ +D K+ DFGL + + + + + APE
Sbjct 921 SMNPPMVHRDLKTLNILISSDWTAKLCDFGLTRTMTMTN--VSTLGMLRGTMAYTAPEIY 978
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
F SDV+S GV ++E + C S +L M + + + R
Sbjct 979 DGLLFNTKSDVYSLGVIMWEAIQRCISGV-----YLRPFHEHPISMDIQIIILTSKNKVR 1033
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182
+ CP ++ L+ CW+ RP + ++ IL T+ + +
Sbjct 1034 PKISENCPEQLKTLITRCWDENPDKRPNCDEILEILLTMKQAHDENKDE 1082
Score = 183 bits (464), Expect = 2e-45, Method: Composition-based stats.
Identities = 59/315 (19%), Positives = 108/315 (34%), Gaps = 55/315 (17%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
H + ++ + +G GT + VY+G+ R + V +
Sbjct 800 HWIPSADLEYIKRIGSGTYSKVYKGKYRDKF--------------------------VAI 833
Query 642 KVLDPSHH--DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
K + S+ + +F + ++S + L +G C+ + MV EY G L L
Sbjct 834 KTMRGSNMTTEQIESFKKECDILSTIQSPLLISFYGSCIEESQLSMVVEYCSKGTLHKVL 893
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKL 757
++ + YL + N +VH ++ NIL++ + KL
Sbjct 894 NNPLLDFDWDKWFKWMTEVVEGVRYLHSMNPPMVHRDLKTLNILIS-------SDWTAKL 946
Query 758 SDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI---CF 809
D G+ + + APE G +T D + G + E C
Sbjct 947 CDFGLTRTMTMTNVSTLGMLRGTMAYTAPEIYDGLL--FNTKSDVYSLGVIMWEAIQRCI 1004
Query 810 DG--EAPLQSRSPSEKEHF------YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861
G P S + + ++ E QL TL ++C P +RP+
Sbjct 1005 SGVYLRPFHEHPISMDIQIIILTSKNKVRPKISENCPEQLKTLITRCWDENPDKRPNCDE 1064
Query 862 ILRDLTRLQPHNLAD 876
IL L ++ + +
Sbjct 1065 ILEILLTMKQAHDEN 1079
>sp|Q9ZWC8|BRL1_ARATH Serine/threonine-protein kinase BRI1-like
1 OS=Arabidopsis thaliana OX=3702 GN=BRL1 PE=1 SV=1
Length=1166
Score = 241 bits (616), Expect = 5e-64, Method: Composition-based stats.
Identities = 76/296 (26%), Positives = 124/296 (42%), Gaps = 22/296 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG+V G +VA+K L G R + E++ + + H +++
Sbjct 865 VGSGGFGEVYKAQLR-----DGSVVAIKKLIRITGQGDRE-FMAEMETIGKIKHRNLVPL 918
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-------IGLAQLLLFAQQICEGMAYLH 1015
G C+ E+ LV EY+ GSL L S + A A G+A+LH
Sbjct 919 LGYCKVGEER--LLVYEYMKWGSLETVLHEKSSKKGGIYLNWAARKKIAIGAARGLAFLH 976
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
H IHRD+ + NVLLD D ++ DFG+A+ V + V +P + PE
Sbjct 977 HSCIPHIIHRDMKSSNVLLDEDFEARVSDFGMARLVSALDTHLSVSTLAGTP-GYVPPEY 1035
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLRLTELLERG 1131
+ ++ DV+S+GV L ELL+ + L+G A+ R E+L+
Sbjct 1036 YQSFRCTAKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAKQLYREKRGAEILDPE 1095
Query 1132 ERLPRP-DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH-EKYQGQAPSVFS 1185
+ D + C + RPT L+ + K + + + ++ FS
Sbjct 1096 LVTDKSGDVELFHYLKIASQCLDDRPFKRPTMIQLMAMFKEMKADTEEDESLDEFS 1151
Score = 211 bits (536), Expect = 3e-54, Method: Composition-based stats.
Identities = 60/329 (18%), Positives = 113/329 (34%), Gaps = 68/329 (21%)
Query 576 LSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L +L+F + + + +G G VY+ +LR
Sbjct 844 LRKLTFAHLLEATNGFSAETMVGSGGFGEVYKAQLRDGS--------------------- 882
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
V +K L F + ++ H +L + G C G E ++V EY++ G
Sbjct 883 ----VVAIKKLIRITGQGDREFMAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKWG 938
Query 694 PLDVWLRRERGH-----VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745
L+ L + + A + +A A L++L + +++H ++ N+LL
Sbjct 939 SLETVLHEKSSKKGGIYLNWAARKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDED 998
Query 746 GLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799
A ++SD G+ LS ++ PE + + D +
Sbjct 999 FEA-------RVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQ--SFRCTAKGDVYS 1049
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQ-----RQHRLPEPSCPQLAT----------- 843
+G LLE+ + + R+ R E P+L T
Sbjct 1050 YGVILLELLSGKKPIDPGEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELFHY 1109
Query 844 --LTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ SQCL P +RP+ ++ ++
Sbjct 1110 LKIASQCLDDRPFKRPTMIQLMAMFKEMK 1138
>sp|Q38997|KIN10_ARATH SNF1-related protein kinase catalytic subunit
alpha KIN10 OS=Arabidopsis thaliana OX=3702 GN=KIN10
PE=1 SV=3
Length=512
Score = 230 bits (586), Expect = 5e-64, Method: Composition-based stats.
Identities = 76/268 (28%), Positives = 111/268 (41%), Gaps = 30/268 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEHI 959
LG G FG+V + + TG VA+K L + + ++EI ILR H HI
Sbjct 24 TLGIGSFGRVKI----AEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPHI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I+ E + + LVMEYV G L DY+ + + + F QQI G+ Y H
Sbjct 80 IRLYEVIETPTD--IYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNM 137
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRDL N+LLD+ VKI DFGL+ + +G + ++ SP + APE + +
Sbjct 138 VVHRDLKPENLLLDSKCNVKIADFGLSNIMRDG---HFLKTSCGSPN-YAAPEVISGKLY 193
Query 1079 -YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
DVWS GV LY LL + L + ++ G P
Sbjct 194 AGPEVDVWSCGVILYALLCGTLPFDDE---------------NIPNLFKKIKGGI-YTLP 237
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165
L+ + R T +
Sbjct 238 SHLSPGARDLIPRMLVVDPMKRVTIPEI 265
Score = 184 bits (467), Expect = 3e-48, Method: Composition-based stats.
Identities = 49/326 (15%), Positives = 95/326 (29%), Gaps = 39/326 (12%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP- 646
LG G+ V + G +V +K+L+
Sbjct 18 NYKLGRTLGIGSFGRVKIAEHALTGH------------------------KVAIKILNRR 53
Query 647 --SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ ++ ++ H H+ ++ V + +V EYV G L ++ E+G
Sbjct 54 KIKNMEMEEKVRREIKILRLFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYI-VEKG 112
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763
+ QQ+ S + Y +VH ++ N+LL +K++D G+
Sbjct 113 RLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSKC-------NVKIADFGLSN 165
Query 764 --LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ + APE + G + +D W G L + P+
Sbjct 166 IMRDGHFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYALLCGTLPFDDENIPN 224
Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
+ + LP P L + L +P +R + I + +
Sbjct 225 LFKKIKGGIYTLPSHLSPGARDLIPRMLVVDPMKRVTIPEIRQHPWFQAHLPRYLAVPPP 284
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGH 907
+ H
Sbjct 285 DTVQQAKKIDEEILQEVINMGFDRNH 310
>sp|P24941|CDK2_HUMAN Cyclin-dependent kinase 2 OS=Homo sapiens
OX=9606 GN=CDK2 PE=1 SV=2
Length=298
Score = 223 bits (567), Expect = 5e-64, Method: Composition-based stats.
Identities = 68/289 (24%), Positives = 122/289 (42%), Gaps = 30/289 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+
Sbjct 1 MENFQKVEKIGEGTYGVV----YKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICE 1009
L H +I+K E L LV E++ L+ ++ I L + + Q+ +
Sbjct 57 ELNHPNIVKLLDVI--HTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQ 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
G+A+ H+ +HRDL +N+L++ + +K+ DFGLA+A R +++ A
Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVP---VRTYTHEVVTLWYRA 170
Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL- 1127
PE L K+Y A D+WS G E++T ++ +L I + T +
Sbjct 171 PEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPG-DSEIDQLFRIFRTLGTPDEVVWPG 229
Query 1128 --LERGERLPRPDKCPCEV-----------YHLMKNCWETEASFRPTFE 1163
+ P + L+ + + R + +
Sbjct 230 VTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAK 278
Score = 171 bits (433), Expect = 5e-46, Method: Composition-based stats.
Identities = 48/266 (18%), Positives = 95/266 (36%), Gaps = 40/266 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
+ ++ +G+GT VY+ R ++ G V LK
Sbjct 1 MENFQKVEKIGEGTYGVVYKARNKLTGE------------------------VVALKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
LD + SL+ +++H ++ + V + +V E++ H L ++
Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-HQDLKKFMDASA 95
Query 704 -GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+P+ QL L++ + ++H ++ +N+L+ G IKL+D G+
Sbjct 96 LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA-------IKLADFGL 148
Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + + APE L G STA+D W G E+
Sbjct 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKY-YSTAVDIWSLGCIFAEMVTRRALFPGDS 207
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ E P + ++
Sbjct 208 EIDQLFRIFRTLGTPDEVVWPGVTSM 233
>sp|A3B529|CIPKS_ORYSJ CBL-interacting protein kinase 28 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK28 PE=2 SV=2
Length=435
Score = 227 bits (579), Expect = 5e-64, Method: Composition-based stats.
Identities = 60/266 (23%), Positives = 109/266 (41%), Gaps = 26/266 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960
LG+G FGKV N +G+ VA+K + + + K+EI I+R + H +++
Sbjct 17 LGQGTFGKVYY----ARNLSSGQSVAIKMIDKEKILKVGLMEQIKREISIMRLVRHPNVL 72
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ + ++ +EY G L + R + + QQ+ M Y H++
Sbjct 73 QLFEVMATKS--NIYFALEYAKGGELFHKMARAKLNEESARNYFQQLISAMDYCHSRGVY 130
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
HRDL N+LLD + +K+ DFGL+ + + +P + APE L +
Sbjct 131 HRDLKPENLLLDENETLKVSDFGLSALAESRRQDGLLHTACGTPA-YVAPEVLSRKGYSG 189
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+DVWS GV L+ L+ + + + ++ + R P
Sbjct 190 SKADVWSCGVILFVLVANYLPFHD--------------RNIIQMYRKIAKAEYR--CPRH 233
Query 1140 CPCEVYHLMKNCWETEASFRPTFENL 1165
E+ L+ + + S R + +
Sbjct 234 FSAELKELLYGILDPDPSTRMSISRI 259
Score = 189 bits (480), Expect = 8e-51, Method: Composition-based stats.
Identities = 59/299 (20%), Positives = 95/299 (32%), Gaps = 43/299 (14%)
Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
+ V + LGQGT VY R G
Sbjct 1 MEERSVLMERYVIGRQLGQGTFGKVYYARNLSSGQS------------------------ 36
Query 639 VVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K++D + S+M V H ++ + V EY + G L
Sbjct 37 VAIKMIDKEKILKVGLMEQIKREISIMRLVRHPNVLQLFEVMATKSNIYFALEYAKGGEL 96
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+ + R + QQL SA+ Y ++ + H ++ N+LL + +
Sbjct 97 --FHKMARAKLNEESARNYFQQLISAMDYCHSRGVYHRDLKPENLLLDE-------NETL 147
Query 756 KLSDPGVGLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
K+SD G+ A SR ++APE L S + D W G L +
Sbjct 148 KVSDFGLSALAESRRQDGLLHTACGTPAYVAPEVLSRKGYS-GSKADVWSCGVILFVLVA 206
Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ + ++R P +L L L +P+ R S I R
Sbjct 207 NYLPFHDRNIIQMYRKIAKAEYRCPRHFSAELKELLYGILDPDPSTRMSISRIKRSAWY 265
>sp|Q9SAJ2|RAF20_ARATH RAF-like serine/threonine-protein kinase
20 OS=Arabidopsis thaliana OX=3702 GN=RAF20 PE=1 SV=1
Length=1248
Score = 241 bits (616), Expect = 5e-64, Method: Composition-based stats.
Identities = 79/299 (26%), Positives = 125/299 (42%), Gaps = 41/299 (14%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-----GPQHRS--GWKQEIDILRTL 954
+LG G FG V + ++ VA+K +K C Q R + E +IL L
Sbjct 969 ELGSGTFGTVYHGKWRGSD------VAIKRIKKSCFAGRSSEQERLTGEFWGEAEILSKL 1022
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMA 1012
+H +++ + G +D +L V EY+ GSLR L R + + L+ A GM
Sbjct 1023 HHPNVVAFYGVVKDGPGGTLATVTEYMVDGSLRHVLVRKDRHLDRRKRLIIAMDAAFGME 1082
Query 1013 YLHAQHYIHRDLAARNVLLD----NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
YLH+++ +H DL N+L++ + + K+GDFGL+K V + W
Sbjct 1083 YLHSKNTVHFDLKCDNLLVNLKDPSRPICKVGDFGLSKI----KRNTLVSGGVRGTLPWM 1138
Query 1069 APECLKE--YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
APE L K DV+SFG+ L+E+LT + + + +
Sbjct 1139 APELLNGSSSKVSEKVDVFSFGIVLWEILTGEEPYANMHYGAI--------------IGG 1184
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG--QAPSV 1183
++ R P C E LM+ CW RP+F + L+ + PS
Sbjct 1185 IVNNTLRPTIPGFCDDEWRTLMEECWAPNPMARPSFTEIAGRLRVMSSAATSTQSKPSA 1243
Score = 239 bits (611), Expect = 2e-63, Method: Composition-based stats.
Identities = 83/382 (22%), Positives = 138/382 (36%), Gaps = 46/382 (12%)
Query 504 KFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLII 563
+ + Q G E G S+ Q + + + + P
Sbjct 879 QLTLGQDYGGNFSEKDGGGTGSIPPALENEQMKVTESEEFGAMVENLRTPDSEPKDEKTE 938
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
R A P + +++ +L LG GT VY G+ R
Sbjct 939 TRHAALPPLGSEFDYSGLQIIKNEDLEELRELGSGTFGTVYHGKWRGSD----------- 987
Query 624 EDPLVPGRDRGQELRVVLKVLDPS--------HHDIALAFYETASLMSQVSHTHLAFVHG 675
V +K + S + F+ A ++S++ H ++ +G
Sbjct 988 ---------------VAIKRIKKSCFAGRSSEQERLTGEFWGEAEILSKLHHPNVVAFYG 1032
Query 676 VCVRGPENIM--VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHG 733
V GP + VTEY+ G L L R+ H+ ++++A A + YL +KN VH
Sbjct 1033 VVKDGPGGTLATVTEYMVDGSLRHVLVRKDRHLDRRKRLIIAMDAAFGMEYLHSKNTVHF 1092
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANS 790
++ N+L+ L + + P K+ D G+ L +PW+APE L G ++
Sbjct 1093 DLKCDNLLV---NLKDPSRPICKVGDFGLSKIKRNTLVSGGVRGTLPWMAPELLNGSSSK 1149
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQ 847
+S +D + FG L EI GE P + + +P + TL +
Sbjct 1150 VSEKVDVFSFGIVLWEIL-TGEEPYANMHYGAIIGGIVNNTLRPTIPGFCDDEWRTLMEE 1208
Query 848 CLTYEPTQRPSFRTILRDLTRL 869
C P RPSF I L +
Sbjct 1209 CWAPNPMARPSFTEIAGRLRVM 1230
>sp|Q63699|CDK2_RAT Cyclin-dependent kinase 2 OS=Rattus norvegicus
OX=10116 GN=Cdk2 PE=1 SV=1
Length=298
Score = 223 bits (567), Expect = 6e-64, Method: Composition-based stats.
Identities = 67/289 (23%), Positives = 122/289 (42%), Gaps = 30/289 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+
Sbjct 1 MENFQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICE 1009
L H +I+K E L LV E++ L+ ++ + L + + Q+ +
Sbjct 57 ELNHPNIVKLLDVI--HTENKLYLVFEFLHQ-DLKKFMDASALTGLPLPLIKSYLFQLLQ 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
G+A+ H+ +HRDL +N+L++ + +K+ DFGLA+A R +++ A
Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVP---VRTYTHEVVTLWYRA 170
Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL- 1127
PE L K+Y A D+WS G E++T ++ +L I + T +
Sbjct 171 PEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPG-DSEIDQLFRIFRTLGTPDEVVWPG 229
Query 1128 --LERGERLPRPDKCPCEV-----------YHLMKNCWETEASFRPTFE 1163
+ P + L+ + + R + +
Sbjct 230 VTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAK 278
Score = 171 bits (432), Expect = 6e-46, Method: Composition-based stats.
Identities = 47/266 (18%), Positives = 95/266 (36%), Gaps = 40/266 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
+ ++ +G+GT VY+ + ++ G V LK
Sbjct 1 MENFQKVEKIGEGTYGVVYKAKNKLTGE------------------------VVALKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
LD + SL+ +++H ++ + V + +V E++ H L ++
Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-HQDLKKFMDASA 95
Query 704 -GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+P+ QL L++ + ++H ++ +N+L+ G IKL+D G+
Sbjct 96 LTGLPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEG-------SIKLADFGL 148
Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + + APE L G STA+D W G E+
Sbjct 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKY-YSTAVDIWSLGCIFAEMVTRRALFPGDS 207
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ E P + ++
Sbjct 208 EIDQLFRIFRTLGTPDEVVWPGVTSM 233
>sp|C0LGG4|Y1518_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g51860 OS=Arabidopsis thaliana OX=3702
GN=At1g51860 PE=2 SV=2
Length=890
Score = 238 bits (607), Expect = 6e-64, Method: Composition-based stats.
Identities = 68/284 (24%), Positives = 118/284 (42%), Gaps = 18/284 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R LG+G FG V D G VAVK L Q +K E+++L +
Sbjct 582 MTNNFERVLGKGGFGTVYHGNLD------GAEVAVKMLSH-SSAQGYKEFKAEVELLLRV 634
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEG 1010
+H H++ G C+D +L L+ EY+ G LR+ + + + A + +G
Sbjct 635 HHRHLVGLVGYCDDGD--NLALIYEYMANGDLRENMSGKRGGNVLTWENRMQIAVEAAQG 692
Query 1011 MAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH +HRD+ N+LL+ K+ DFGL+++ P E + +P +
Sbjct 693 LEYLHNGCRPPMVHRDVKTTNILLNERCGAKLADFGLSRSFPIDGECHVSTVVAGTP-GY 751
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
PE + SDV+SFGV L E++T+ + + +T + +
Sbjct 752 LDPEYYRTNWLSEKSDVYSFGVVLLEIVTNQPVIDKTRER-PHINDWVGFMLTKGDIKSI 810
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
++ ++ L C ++ RPT +++ L
Sbjct 811 VDPKLMGDYDTNGAWKIVELALACVNPSSNRRPTMAHVVMELND 854
Score = 209 bits (531), Expect = 3e-54, Method: Composition-based stats.
Identities = 73/344 (21%), Positives = 119/344 (35%), Gaps = 62/344 (18%)
Query 553 PQPGETSNLIIMRGARASPRTLNL-SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
P P T ++ ++P + ++++ V + LG+G VY G L
Sbjct 547 PPPLVTPGIVKSETRSSNPSIITRERKITYPEVLKMTNNFERVLGKGGFGTVYHGNL--- 603
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
V +K+L S F L+ +V H HL
Sbjct 604 -----------------------DGAEVAVKMLSHSSAQGYKEFKAEVELLLRVHHRHLV 640
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN-- 727
+ G C G ++ EY+ +G L + +RG + W +M +A + A L YL N
Sbjct 641 GLVGYCDDGDNLALIYEYMANGDLRENMSGKRGGNVLTWENRMQIAVEAAQGLEYLHNGC 700
Query 728 -KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR------EERVERIPWLA 780
+VH +V NILL A KL+D G+ +L
Sbjct 701 RPPMVHRDVKTTNILLNERCGA-------KLADFGLSRSFPIDGECHVSTVVAGTPGYLD 753
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR---SPSEKEHFYQRQHRLPEPS 837
PE N LS D + FG LLEI + ++R ++ F + +
Sbjct 754 PEYYRT--NWLSEKSDVYSFGVVLLEIVTNQPVIDKTRERPHINDWVGFMLTKGDIKSIV 811
Query 838 CPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRL 869
P+L L C+ +RP+ ++ +L
Sbjct 812 DPKLMGDYDTNGAWKIVELALACVNPSSNRRPTMAHVVMELNDC 855
>sp|Q8VZJ9|CRCK2_ARATH Calmodulin-binding receptor-like cytoplasmic
kinase 2 OS=Arabidopsis thaliana OX=3702 GN=CRCK2 PE=2
SV=1
Length=411
Score = 226 bits (577), Expect = 6e-64, Method: Composition-based stats.
Identities = 80/319 (25%), Positives = 121/319 (38%), Gaps = 19/319 (6%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ + D + +G+G FG V G+ AVK
Sbjct 93 QRSYGNANETEHTRFTFDEIYDATKNFSPSFRIGQGGFGTVYKVKLR-----DGKTFAVK 147
Query 931 ALKA---DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
K D + + EI L + H ++KY G EK LV+EYV G+LR
Sbjct 148 RAKKSMHDDRQGADAEFMSEIQTLAQVTHLSLVKYYGFVVHNDEK--ILVVEYVANGTLR 205
Query 988 DYL---PRHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGD 1041
D+L ++ +A L A + + YLH IHRD+ + N+LL + K+ D
Sbjct 206 DHLDCKEGKTLDMATRLDIATDVAHAITYLHMYTQPPIIHRDIKSSNILLTENYRAKVAD 265
Query 1042 FGLAKAVPEGHE-YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100
FG A+ P+ V + PE L Y+ SDV+SFGV L ELLT
Sbjct 266 FGFARLAPDTDSGATHVSTQVKGTAGYLDPEYLTTYQLTEKSDVYSFGVLLVELLTGRRP 325
Query 1101 SQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK-CPCEVYHLMKNCWETEASF 1158
+ S K I A + T +L+ + +V + C
Sbjct 326 IELSRGQKERITIRWAIKKFTSGDTISVLDPKLEQNSANNLALEKVLEMAFQCLAPHRRS 385
Query 1159 RPTFENLIPILKTVHEKYQ 1177
RP+ + IL + + Y+
Sbjct 386 RPSMKKCSEILWGIRKDYR 404
Score = 197 bits (500), Expect = 1e-53, Method: Composition-based stats.
Identities = 63/343 (18%), Positives = 113/343 (33%), Gaps = 62/343 (18%)
Query 564 MRGARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
++ + + ++ +F + K + +GQG VY+ +LR + +
Sbjct 92 VQRSYGNANETEHTRFTFDEIYDATKNFSPSFRIGQGGFGTVYKVKLRDGKTFAVKR--- 148
Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
K + F ++QV+H L +G V
Sbjct 149 ------------------AKKSMHDDRQGADAEFMSEIQTLAQVTHLSLVKYYGFVVHND 190
Query 682 ENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCG 737
E I+V EYV +G L L + G + MA ++ +A +A A++YL ++H ++
Sbjct 191 EKILVVEYVANGTLRDHLDCKEGKTLDMATRLDIATDVAHAITYLHMYTQPPIIHRDIKS 250
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREE--------RVERIPWLAPECLPGGAN 789
NILL + K++D G A + +L PE L
Sbjct 251 SNILLTE-------NYRAKVADFGFARLAPDTDSGATHVSTQVKGTAGYLDPEYLTT--Y 301
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC----------- 838
L+ D + FG L+E+ SR E+ +
Sbjct 302 QLTEKSDVYSFGVLLVELLTGRRPIELSRGQKERITIRWAIKKFTSGDTISVLDPKLEQN 361
Query 839 -------PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
++ + QCL RPS + L ++
Sbjct 362 SANNLALEKVLEMAFQCLAPHRRSRPSMKKCSEILWGIRKDYR 404
>sp|Q8GYF5|WAKLR_ARATH Wall-associated receptor kinase-like 21
OS=Arabidopsis thaliana OX=3702 GN=WAKL21 PE=2 SV=2
Length=622
Score = 233 bits (593), Expect = 6e-64, Method: Composition-based stats.
Identities = 69/314 (22%), Positives = 126/314 (40%), Gaps = 20/314 (6%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
LG G +G V + ++ VA+K LK
Sbjct 300 PFYTYKEIEKATDSFSDKNMLGTGAYGTVYAGEFPNSS-----CVAIKRLKHKDTT-SID 353
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----SIGLA 998
EI +L ++ H ++++ GCC GE LV E++P G+L +L +
Sbjct 354 QVVNEIKLLSSVSHPNLVRLLGCCFADGEP--FLVYEFMPNGTLYQHLQHERGQPPLSWQ 411
Query 999 QLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKA-VPEGHEY 1054
L A Q +A+LH+ HRD+ + N+LLD++ KI DFGL++ + E
Sbjct 412 LRLAIACQTANAIAHLHSSVNPPIYHRDIKSSNILLDHEFNSKISDFGLSRLGMSTDFEA 471
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIG 1113
+ + P+ ++++ SDV+SFGV L E+++ + P + L
Sbjct 472 SHISTAPQGTPGYLDPQYHQDFQLSDKSDVYSFGVVLVEIISGFKVIDFTRPYSEVNLAS 531
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170
+A ++ R+ ++++ K +++L + C + RPT + L
Sbjct 532 LAVDRIGRGRVVDIIDPCLNKEINPKMFASIHNLAELAFRCLSFHRNMRPTMVEITEDLH 591
Query 1171 TVHEKYQGQAPSVF 1184
+ + G F
Sbjct 592 RIKLMHYGTESGKF 605
Score = 210 bits (535), Expect = 2e-56, Method: Composition-based stats.
Identities = 69/380 (18%), Positives = 122/380 (32%), Gaps = 60/380 (16%)
Query 544 CFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRT 601
F ++ + +N ++ A S ++ ++ + + LG G
Sbjct 271 FFRNKQSASSERASIANRLLCELAGNSSVPF----YTYKEIEKATDSFSDKNMLGTGAYG 326
Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL 661
VY G + V +K L L
Sbjct 327 TVYAG-------------------------EFPNSSCVAIKRLKHKDTTSIDQVVNEIKL 361
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLA 719
+S VSH +L + G C E +V E++ +G L L+ ERG P++W ++ +A Q A
Sbjct 362 LSSVSHPNLVRLLGCCFADGEPFLVYEFMPNGTLYQHLQHERGQPPLSWQLRLAIACQTA 421
Query 720 SALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV--- 773
+A+++L + + H ++ NILL + K+SD G+ +S +
Sbjct 422 NAIAHLHSSVNPPIYHRDIKSSNILLDHEFNS-------KISDFGLSRLGMSTDFEASHI 474
Query 774 -----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
+L P+ LS D + FG L+EI + +R SE
Sbjct 475 STAPQGTPGYLDPQY--HQDFQLSDKSDVYSFGVVLVEIISGFKVIDFTRPYSEVNLASL 532
Query 829 RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASD 888
R+ ++ + CL E + + N +
Sbjct 533 AVDRIGRG---RVVDIIDPCLNKEINPKMFASI----HNLAELAFRCLSFHRNMRPTMVE 585
Query 889 PTVFHKRYLKKIRDLGEGHF 908
T R G F
Sbjct 586 ITEDLHRIKLMHYGTESGKF 605
>sp|O55076|CDK2_CRIGR Cyclin-dependent kinase 2 OS=Cricetulus
griseus OX=10029 GN=CDK2 PE=1 SV=1
Length=298
Score = 222 bits (566), Expect = 6e-64, Method: Composition-based stats.
Identities = 68/289 (24%), Positives = 122/289 (42%), Gaps = 30/289 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+
Sbjct 1 MENFQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICE 1009
L H +I+K E L LV E++ L+ ++ I L + + Q+ +
Sbjct 57 ELNHPNIVKLLDVI--HTENKLYLVFEFLHQ-DLKKFMDASAVTGIPLPLIKSYLFQLLQ 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
G+A+ H+ +HRDL +N+L++ + +K+ DFGLA+A R +++ A
Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVP---VRTYTHEVVTLWYRA 170
Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL- 1127
PE L K+Y A D+WS G E++T ++ +L I + T +
Sbjct 171 PEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPG-DSEIDQLFRIFRTLGTPDEVVWPG 229
Query 1128 --LERGERLPRPDKCPCEV-----------YHLMKNCWETEASFRPTFE 1163
+ P + L+ + + R + +
Sbjct 230 VTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAK 278
Score = 171 bits (432), Expect = 7e-46, Method: Composition-based stats.
Identities = 47/266 (18%), Positives = 95/266 (36%), Gaps = 40/266 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
+ ++ +G+GT VY+ + ++ G V LK
Sbjct 1 MENFQKVEKIGEGTYGVVYKAKNKLTGE------------------------VVALKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
LD + SL+ +++H ++ + V + +V E++ H L ++
Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-HQDLKKFMDASA 95
Query 704 -GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+P+ QL L++ + ++H ++ +N+L+ G IKL+D G+
Sbjct 96 VTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEG-------SIKLADFGL 148
Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + + APE L G STA+D W G E+
Sbjct 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKY-YSTAVDIWSLGCIFAEMVTRRALFPGDS 207
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ E P + ++
Sbjct 208 EIDQLFRIFRTLGTPDEVVWPGVTSM 233
>sp|Q9LWM4|CIPK5_ORYSJ CBL-interacting protein kinase 5 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK5 PE=2 SV=1
Length=461
Score = 228 bits (581), Expect = 6e-64, Method: Composition-based stats.
Identities = 60/268 (22%), Positives = 112/268 (42%), Gaps = 26/268 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960
LG+G F KV Y N + + VA+K + + + K+EI I+R + H +I+
Sbjct 18 LGQGTFAKV----YHARNLASNQSVAIKVIDKEKVLRVGMIDQIKREISIMRLVRHPNIV 73
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ + + + MEYV G L + R + + QQ+ + + H++
Sbjct 74 QLHEVMASKSK--IYFAMEYVRGGELFSRVARGRLKEDAARKYFQQLIGAVDFCHSRGVY 131
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
HRDL N+L+D + +K+ DFGL+ + + +P + APE + + +
Sbjct 132 HRDLKPENLLVDENGNLKVSDFGLSAFKECQKQDGLLHTTCGTPA-YVAPEIINKRGYDG 190
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS GV L+ LL ++ + + +G+ + P
Sbjct 191 AKADIWSCGVILFVLLAGYLPFHD---------------SNLMEMYRKISKGD-VKFPQW 234
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+V L+ + + R T E L+
Sbjct 235 FTTDVRRLLSRLLDPNPNIRITVEKLVE 262
Score = 184 bits (468), Expect = 6e-49, Method: Composition-based stats.
Identities = 58/331 (18%), Positives = 102/331 (31%), Gaps = 45/331 (14%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ LGQGT VY R+ V +KV
Sbjct 7 ILMNRYELGRMLGQGTFAKVYHA------------------------RNLASNQSVAIKV 42
Query 644 LDPSHH---DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
+D + S+M V H ++ +H V + EYV G L R
Sbjct 43 IDKEKVLRVGMIDQIKREISIMRLVRHPNIVQLHEVMASKSKIYFAMEYVRGGELFS--R 100
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
RG + QQL A+ + ++ + H ++ N+L+ G +K+SD
Sbjct 101 VARGRLKEDAARKYFQQLIGAVDFCHSRGVYHRDLKPENLLVDENG-------NLKVSDF 153
Query 761 GVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ ++ ++APE + D W G L + G P
Sbjct 154 GLSAFKECQKQDGLLHTTCGTPAYVAPEIINKRGYD-GAKADIWSCGVIL-FVLLAGYLP 211
Query 815 LQSRSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
+ E + + P+ + L S+ L P R + ++ + +
Sbjct 212 FHDSNLMEMYRKISKGDVKFPQWFTTDVRRLLSRLLDPNPNIRITVEKLVEHPWFKKGYK 271
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
A +L+ +S K +
Sbjct 272 PAVMLSQPNESNNLKDVHTAFSADHKDNEGK 302
>sp|P11345|RAF1_RAT RAF proto-oncogene serine/threonine-protein
kinase OS=Rattus norvegicus OX=10116 GN=Raf1 PE=1 SV=1
Length=648
Score = 233 bits (594), Expect = 6e-64, Method: Composition-based stats.
Identities = 81/333 (24%), Positives = 135/333 (41%), Gaps = 35/333 (11%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
+ T P+ R + + +S + +G G F
Sbjct 305 WSQPKTPVPAQRERAPGSGT----QEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF 360
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
G V + VAVK LK D P+ ++ E+ +LR H +I+ + G
Sbjct 361 GTVYKGKWHG-------DVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILLFMGYM- 412
Query 968 DQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
+ +L +V ++ SL +L + QL+ A+Q +GM YLHA++ IHRD+
Sbjct 413 --TKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMK 470
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYAS 1082
+ N+ L VKIGDFGLA +V E V W APE ++ F + S
Sbjct 471 SNNIFLHEGLTVKIGDFGLATVKSRWSGSQQV-EQPTGSVLWMAPEVIRMQDNNPFSFQS 529
Query 1083 DVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
DV+S+G+ LYEL+T + + ++G + RL + C
Sbjct 530 DVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSRLYK------------NC 577
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
P + L+ +C + RP F ++ ++ +
Sbjct 578 PKAMKRLVADCVKKVKEERPLFPQILSSIELLQ 610
Score = 223 bits (569), Expect = 1e-60, Method: Composition-based stats.
Identities = 70/367 (19%), Positives = 127/367 (35%), Gaps = 62/367 (17%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
R + N I RG R S + ++ E+ + +G G+ VY+G+
Sbjct 316 RERAPGSGTQEKNKIRPRGQRDSSY--------YWEIEASEVMLSTRIGSGSFGTVYKGK 367
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQ 664
+ V +K+L DP+ + AF +++ +
Sbjct 368 WHGD---------------------------VAVKILKVVDPTPEQLQ-AFRNEVAVLRK 399
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
H ++ G + +VT++ E L L + M + +A+Q A + Y
Sbjct 400 TRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778
L KN++H ++ NI L +K+ D G+ G+ E+ + W
Sbjct 459 LHAKNIIHRDMKSNNIFLHEGL-------TVKIGDFGLATVKSRWSGSQQVEQPTGSVLW 511
Query 779 LAPECLPGGA-NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------ 831
+APE + N S D + +G L E+ GE P + ++ F +
Sbjct 512 MAPEVIRMQDNNPFSFQSDVYSYGIVLYELM-TGELPYSHINNRDQIIFMVGRGYASPDL 570
Query 832 -RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
RL + + L + C+ +RP F IL + LQ + + S
Sbjct 571 SRLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAH 630
Query 891 VFHKRYL 897
Sbjct 631 TEDINAC 637
>sp|Q9SNA3|Y3463_ARATH Putative receptor-like protein kinase At3g46340
OS=Arabidopsis thaliana OX=3702 GN=At3g46340 PE=1 SV=1
Length=889
Score = 238 bits (607), Expect = 6e-64, Method: Composition-based stats.
Identities = 70/344 (20%), Positives = 132/344 (38%), Gaps = 17/344 (5%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
+P+ ++ + + R LGEG FG
Sbjct 538 KKKPSNLEDLPPSSNTPRENITSTSISDTSIETKRKRFSYSEVMEMTKNLQRPLGEGGFG 597
Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
V +G+ + VAVK L + Q +K E+++L ++H +++ G C+++
Sbjct 598 VVYHGDI----NGSSQQVAVK-LLSQSSTQGYKEFKAEVELLLRVHHINLVSLVGYCDER 652
Query 970 GEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLH---AQHYIHR 1022
L L+ EY+ L+ +L + L A G+ YLH +HR
Sbjct 653 DH--LALIYEYMSNKDLKHHLSGKHGGSVLKWNTRLQIAVDAALGLEYLHIGCRPSMVHR 710
Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082
D+ + N+LLD+ K+ DFGL+++ G E +P + PE + + S
Sbjct 711 DVKSTNILLDDQFTAKMADFGLSRSFQLGDESQVSTVVAGTP-GYLDPEYYRTGRLAEMS 769
Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
DV+SFG+ L E++T+ P + + + +T +++ + +
Sbjct 770 DVYSFGIVLLEIITNQRVI-DPAREKSHITEWTAFMLNRGDITRIMDPNLQGDYNSRSVW 828
Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKT-VHEKYQGQAPSVFS 1185
L C + RP+ ++ LK + + + Q S
Sbjct 829 RALELAMMCANPSSEKRPSMSQVVIELKECIRSENKTQGMDSHS 872
Score = 208 bits (530), Expect = 4e-54, Method: Composition-based stats.
Identities = 68/337 (20%), Positives = 106/337 (31%), Gaps = 59/337 (18%)
Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
P I + + S+ V + LG+G VY G +
Sbjct 548 PPSSNTPRENITSTSISDTSIETKRKRFSYSEVMEMTKNLQRPLGEGGFGVVYHGDI--- 604
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
G +V +K+L S F L+ +V H +L
Sbjct 605 ---------------------NGSSQQVAVKLLSQSSTQGYKEFKAEVELLLRVHHINLV 643
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE--- 726
+ G C ++ EY+ + L L + G + W ++ +A A L YL
Sbjct 644 SLVGYCDERDHLALIYEYMSNKDLKHHLSGKHGGSVLKWNTRLQIAVDAALGLEYLHIGC 703
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLA 780
++VH +V NILL A K++D G+ +E +L
Sbjct 704 RPSMVHRDVKSTNILLDDQFTA-------KMADFGLSRSFQLGDESQVSTVVAGTPGYLD 756
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS---EKEHFYQRQHRLPEPS 837
PE G L+ D + FG LLEI + +R S E F + +
Sbjct 757 PEYYRTG--RLAEMSDVYSFGIVLLEIITNQRVIDPAREKSHITEWTAFMLNRGDITRIM 814
Query 838 CPQL------------ATLTSQCLTYEPTQRPSFRTI 862
P L L C +RPS +
Sbjct 815 DPNLQGDYNSRSVWRALELAMMCANPSSEKRPSMSQV 851
>sp|P93050|RKF3_ARATH Probable LRR receptor-like serine/threonine-protein
kinase RKF3 OS=Arabidopsis thaliana OX=3702 GN=RKF3
PE=2 SV=1
Length=617
Score = 232 bits (592), Expect = 7e-64, Method: Composition-based stats.
Identities = 72/288 (25%), Positives = 126/288 (44%), Gaps = 20/288 (7%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+ +G G +G V G VA K K +C + + E++++ ++
Sbjct 281 NNFSRHNIIGRGGYGNVFKGAL-----PDGTQVAFKRFK-NCSAGGDANFAHEVEVIASI 334
Query 955 YHEHIIKYKGCCED----QGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQI 1007
H +++ +G C +G + + +V + V GSL D+L + A +
Sbjct 335 RHVNLLALRGYCTATTPYEGHQRI-IVCDLVSNGSLHDHLFGDLEAQLAWPLRQRIALGM 393
Query 1008 CEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
G+AYLH IHRD+ A N+LLD K+ DFGLAK PEG + R G
Sbjct 394 ARGLAYLHYGAQPSIIHRDIKASNILLDERFEAKVADFGLAKFNPEGMTHMSTRVAG--T 451
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLR 1123
+ + APE + SDV+SFGV L ELL+ + + + + + A + +
Sbjct 452 MGYVAPEYALYGQLTEKSDVYSFGVVLLELLSRRKAIVTDEEGQPVSVADWAWSLVREGQ 511
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+++E G P + + + C + RPT + ++ +L++
Sbjct 512 TLDVVEDGMPEKGPPEVLEKYVLIAVLCSHPQLHARPTMDQVVKMLES 559
Score = 197 bits (501), Expect = 5e-52, Method: Composition-based stats.
Identities = 67/385 (17%), Positives = 126/385 (33%), Gaps = 68/385 (18%)
Query 554 QPGETSNLIIMRGARAS-PRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRV 610
+P +TS + S + L + SF + ++ + +G+G NV++G L
Sbjct 245 KPRDTSLEAGTQSRLDSMSESTTLVKFSFDEIKKATNNFSRHNIIGRGGYGNVFKGALPD 304
Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670
+V K F +++ + H +L
Sbjct 305 G-------------------------TQVAFKRFKNCSAGGDANFAHEVEVIASIRHVNL 339
Query 671 AFVHGVCV-----RGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSY 724
+ G C G + I+V + V +G L L + + + +A +A L+Y
Sbjct 340 LALRGYCTATTPYEGHQRIIVCDLVSNGSLHDHLFGDLEAQLAWPLRQRIALGMARGLAY 399
Query 725 LE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERV-ERI 776
L +++H ++ NILL A K++D G+ G RV +
Sbjct 400 LHYGAQPSIIHRDIKASNILLDERFEA-------KVADFGLAKFNPEGMTHMSTRVAGTM 452
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE-------------APLQSRSPSEK 823
++APE G L+ D + FG LLE+ + A E
Sbjct 453 GYVAPEYALYG--QLTEKSDVYSFGVVLLELLSRRKAIVTDEEGQPVSVADWAWSLVREG 510
Query 824 EHFYQRQHRLPEPSCPQLAT----LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
+ + +PE P++ + C + RP+ +++ L + +A
Sbjct 511 QTLDVVEDGMPEKGPPEVLEKYVLIAVLCSHPQLHARPTMDQVVKMLESNEFTVIAIPQR 570
Query 880 VNPDSPASDPTVFHKRYLKKIRDLG 904
P + L
Sbjct 571 PIPLVACREEIDRSVSSSSGSGKLT 595
>sp|Q5R8X7|M3K13_PONAB Mitogen-activated protein kinase kinase
kinase 13 OS=Pongo abelii OX=9601 GN=MAP3K13 PE=2 SV=1
Length=966
Score = 239 bits (609), Expect = 7e-64, Method: Composition-based stats.
Identities = 83/301 (28%), Positives = 121/301 (40%), Gaps = 35/301 (12%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ + + D + +++ LG G G V L + E VA+K
Sbjct 142 WNIIGKAYATDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRA------EEVAIK 195
Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
++ I LR L H +II +KG C ++MEY G L + L
Sbjct 196 KVREQNETD--------IKHLRKLKHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVL 245
Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
I L+ ++ I GM YLH IHRDL + NVL+ + VKI DFG +K +
Sbjct 246 RAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELS 305
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
+ + V W APE ++ D+WSFGV L+ELLT P K +
Sbjct 306 D----KSTKMSFAGTVAWLAPEVIRNEPVSEKVDIWSFGVVLWELLTG-----EIPYKDV 356
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ I G + LP P CP LMK W+++ RP+F + L
Sbjct 357 DSSAIIWGVGSN---------SLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHL 407
Query 1170 K 1170
Sbjct 408 D 408
Score = 211 bits (538), Expect = 6e-55, Method: Composition-based stats.
Identities = 66/305 (22%), Positives = 109/305 (36%), Gaps = 50/305 (16%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+A L Q V +EI++L LG G + V+ G+ R E
Sbjct 146 GKAYATDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAE--------------- 190
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
V +K + + + ++ H ++ GVC + P ++
Sbjct 191 -----------EVAIKKVREQNE-------TDIKHLRKLKHPNIIAFKGVCTQAPCYCII 232
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
EY HG L LR R + + + +AS ++YL ++H ++ N+L+
Sbjct 233 MEYCAHGQLYEVLRAGR-KITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTD 291
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+K+SD G + ++ + WLAPE + +S +D W FG
Sbjct 292 A-------VKISDFGTSKELSDKSTKMSFAGTVAWLAPEVIRN--EPVSEKVDIWSFGVV 342
Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
L E+ GE P + S +P L Q +P RPSFR
Sbjct 343 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFR 401
Query 861 TILRD 865
L
Sbjct 402 QTLMH 406
>sp|Q852Q2|OSK1_ORYSJ Serine/threonine protein kinase OSK1 OS=Oryza
sativa subsp. japonica OX=39947 GN=OSK1 PE=1 SV=1
Length=505
Score = 229 bits (584), Expect = 7e-64, Method: Composition-based stats.
Identities = 76/268 (28%), Positives = 111/268 (41%), Gaps = 30/268 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEHI 959
LG G FGKV + + TG VA+K L + + K+EI ILR H HI
Sbjct 19 TLGIGSFGKVKI----AEHILTGHKVAIKILNRRKIKSMEMEEKVKREIKILRLFMHPHI 74
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I+ + + + +VMEYV G L DY+ + + + F QQI G+ Y H
Sbjct 75 IRLYEVIDTPAD--IYVVMEYVKSGELFDYIVEKGRLQEEEARRFFQQIISGVEYCHRNM 132
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRDL N+LLD+ VKI DFGL+ + +G + ++ SP + APE + +
Sbjct 133 VVHRDLKPENLLLDSKCNVKIADFGLSNVMRDG---HFLKTSCGSPN-YAAPEVISGKLY 188
Query 1079 -YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
DVWS GV LY LL + L + ++ G P
Sbjct 189 AGPEVDVWSCGVILYALLCGTLPFDDE---------------NIPNLFKKIKGGI-YTLP 232
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165
L+ + R T +
Sbjct 233 SHLSPLARDLIPRMLVVDPMKRITIREI 260
Score = 180 bits (456), Expect = 5e-47, Method: Composition-based stats.
Identities = 49/321 (15%), Positives = 94/321 (29%), Gaps = 39/321 (12%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP--- 646
LG G+ V + G +V +K+L+
Sbjct 15 RIGKTLGIGSFGKVKIAEHILTGH------------------------KVAIKILNRRKI 50
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
++ ++ H H+ ++ V + +V EYV+ G L ++ E+G +
Sbjct 51 KSMEMEEKVKREIKILRLFMHPHIIRLYEVIDTPADIYVVMEYVKSGELFDYI-VEKGRL 109
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--- 763
QQ+ S + Y +VH ++ N+LL +K++D G+
Sbjct 110 QEEEARRFFQQIISGVEYCHRNMVVHRDLKPENLLLDSKC-------NVKIADFGLSNVM 162
Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ + APE + G + +D W G L + P+
Sbjct 163 RDGHFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYALLCGTLPFDDENIPNLF 221
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
+ + LP P L + L +P +R + R I +
Sbjct 222 KKIKGGIYTLPSHLSPLARDLIPRMLVVDPMKRITIREIREHQWFTVGLPRYLAVPPPDT 281
Query 884 SPASDPTVFHKRYLKKIRDLG 904
+
Sbjct 282 AQQVKKLDDETLNDVINMGFD 302
>sp|C0LGP2|MEE39_ARATH Probable LRR receptor-like serine/threonine-protein
kinase MEE39 OS=Arabidopsis thaliana OX=3702 GN=MEE39
PE=1 SV=1
Length=878
Score = 238 bits (606), Expect = 7e-64, Method: Composition-based stats.
Identities = 66/293 (23%), Positives = 118/293 (40%), Gaps = 16/293 (5%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
+ + R LGEG FG V + + E VAVK L + Q +K
Sbjct 555 RFTYSEVMEMTKNLQRPLGEGGFGVVYHGDLNGS-----EQVAVK-LLSQTSAQGYKEFK 608
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLL 1001
E+++L ++H +++ G C++Q L+ EY+ G L +L + L
Sbjct 609 AEVELLLRVHHINLVNLVGYCDEQDH--FALIYEYMSNGDLHQHLSGKHGGSVLNWGTRL 666
Query 1002 LFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
A + G+ YLH +HRD+ + N+LLD + KI DFGL+++ G + +V
Sbjct 667 QIAIEAALGLEYLHTGCKPAMVHRDVKSTNILLDEEFKAKIADFGLSRSFQVGGDQSQVS 726
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
+ + PE + SDV+SFG+ L E++T+ + +
Sbjct 727 TVVAGTLGYLDPEYYLTSELSEKSDVYSFGILLLEIITNQRVIDQT-RENPNIAEWVTFV 785
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ +++++ + +C + RP +I LK
Sbjct 786 IKKGDTSQIVDPKLHGNYDTHSVWRALEVAMSCANPSSVKRPNMSQVIINLKE 838
Score = 210 bits (535), Expect = 9e-55, Method: Composition-based stats.
Identities = 63/320 (20%), Positives = 109/320 (34%), Gaps = 61/320 (19%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+ ++ V + LG+G VY G L
Sbjct 554 KRFTYSEVMEMTKNLQRPLGEGGFGVVYHGDLNGSE------------------------ 589
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+V +K+L + F L+ +V H +L + G C ++ EY+ +G L
Sbjct 590 -QVAVKLLSQTSAQGYKEFKAEVELLLRVHHINLVNLVGYCDEQDHFALIYEYMSNGDLH 648
Query 697 VWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGT 751
L + G + W ++ +A + A L YL +VH +V NILL A
Sbjct 649 QHLSGKHGGSVLNWGTRLQIAIEAALGLEYLHTGCKPAMVHRDVKSTNILLDEEFKA--- 705
Query 752 SPFIKLSDPGVGLG-------ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
K++D G+ + + +L PE + LS D + FG L
Sbjct 706 ----KIADFGLSRSFQVGGDQSQVSTVVAGTLGYLDPEYYLT--SELSEKSDVYSFGILL 759
Query 805 LEICFDGEAPLQSRSP---SEKEHFYQRQHRLPEPSCPQLA------------TLTSQCL 849
LEI + Q+R +E F ++ + P+L + C
Sbjct 760 LEIITNQRVIDQTRENPNIAEWVTFVIKKGDTSQIVDPKLHGNYDTHSVWRALEVAMSCA 819
Query 850 TYEPTQRPSFRTILRDLTRL 869
+RP+ ++ +L
Sbjct 820 NPSSVKRPNMSQVIINLKEC 839
>sp|Q9SEZ7|CIPKG_ARATH CBL-interacting serine/threonine-protein
kinase 16 OS=Arabidopsis thaliana OX=3702 GN=CIPK16 PE=1 SV=1
Length=469
Score = 228 bits (581), Expect = 7e-64, Method: Composition-based stats.
Identities = 68/275 (25%), Positives = 114/275 (41%), Gaps = 35/275 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR---SGWKQEIDILRTLYHEHI 959
LG G+F KV Y T TG+ VA+K +K D + R ++EI ++R L H ++
Sbjct 21 LGTGNFAKV----YHGTEISTGDDVAIKVIKKDHVFKRRGMMEQIEREIAVMRLLRHPNV 76
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQH 1018
++ + + K + VMEYV G L + + R + + QQ+ + + H++
Sbjct 77 VELREVMATK--KKIFFVMEYVNGGELFEMIDRDGKLPEDLARKYFQQLISAVDFCHSRG 134
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-------GHEYYRVREDGDSPVFWYAPE 1071
HRD+ N+LLD + +K+ DFGL+ + G + +P + APE
Sbjct 135 VFHRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRRGSSDDLLHTRCGTPA-YVAPE 193
Query 1072 CLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
L+ + A +D+WS G+ LY LL I + MT+ E
Sbjct 194 VLRNKGYDGAMADIWSCGIVLYALLAGFLPF------------IDENVMTLYTKIFKAE- 240
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P E L+ + R + +
Sbjct 241 ---CEFPPWFSLESKELLSRLLVPDPEQRISMSEI 272
Score = 181 bits (459), Expect = 1e-47, Method: Composition-based stats.
Identities = 58/342 (17%), Positives = 103/342 (30%), Gaps = 50/342 (15%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
V + LG G VY G G V +K
Sbjct 9 TVLFDKYNIGRLLGTGNFAKVYHGTEISTGDD------------------------VAIK 44
Query 643 VLDPSH----HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V+ H + ++M + H ++ + V + V EYV G L
Sbjct 45 VIKKDHVFKRRGMMEQIEREIAVMRLLRHPNVVELREVMATKKKIFFVMEYVNGGELFEM 104
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ G +P QQL SA+ + ++ + H ++ N+LL G +K++
Sbjct 105 I-DRDGKLPEDLARKYFQQLISAVDFCHSRGVFHRDIKPENLLLDGEGD-------LKVT 156
Query 759 DPGVG-----------LGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
D G+ G+ R ++APE L D W G L
Sbjct 157 DFGLSALMMPEGLGGRRGSSDDLLHTRCGTPAYVAPEVLRNKGYD-GAMADIWSCGIVLY 215
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ + + ++ + P + L S+ L +P QR S I
Sbjct 216 ALLAGFLPFIDENVMTLYTKIFKAECEFPPWFSLESKELLSRLLVPDPEQRISMSEIKMI 275
Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
+ + +++ P+ K+ +G
Sbjct 276 PWFRKNFTPSVAFSIDETIPSPPEPPTKKKKKDLNEKEDDGA 317
>sp|Q9M2Z1|BAME2_ARATH Leucine-rich repeat receptor-like serine/threonine-protein
kinase BAM2 OS=Arabidopsis thaliana OX=3702
GN=BAM2 PE=1 SV=1
Length=1002
Score = 239 bits (610), Expect = 8e-64, Method: Composition-based stats.
Identities = 81/312 (26%), Positives = 126/312 (40%), Gaps = 17/312 (5%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
L+ + A + LK+ +G+G G V G++VA
Sbjct 662 LRNASEAKAWRLTAFQRLDFTCDDVLDSLKEDNIIGKGGAGIVYKGTMPK-----GDLVA 716
Query 929 VKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
VK L G H G+ EI L + H HI++ G C + LV EY+P GSL
Sbjct 717 VKRLATMSHGSSHDHGFNAEIQTLGRIRHRHIVRLLGFCSNHETN--LLVYEYMPNGSLG 774
Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGD 1041
+ L + A + +G+ YLH +HRD+ + N+LLD++ + D
Sbjct 775 EVLHGKKGGHLHWNTRYKIALEAAKGLCYLHHDCSPLIVHRDVKSNNILLDSNFEAHVAD 834
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLAK + + + S + APE K SDV+SFGV L EL+T
Sbjct 835 FGLAKFLQDSGTSECMSAIAGS-YGYIAPEYAYTLKVDEKSDVYSFGVVLLELITGKKPV 893
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERL-PRPDKCPCEVYHLMKNCWETEASFRP 1160
++++ + + L RL P V+++ C E +A RP
Sbjct 894 GE-FGDGVDIVQWVRSMTDSNKDCVLKVIDLRLSSVPVHEVTHVFYVALLCVEEQAVERP 952
Query 1161 TFENLIPILKTV 1172
T ++ IL +
Sbjct 953 TMREVVQILTEI 964
Score = 196 bits (499), Expect = 6e-50, Method: Composition-based stats.
Identities = 64/345 (19%), Positives = 119/345 (34%), Gaps = 70/345 (20%)
Query 561 LIIMRGARASPRTLNLSQLSFHRVDQ------KEITQLSHLGQGTRTNVYEGRLRVEGSG 614
+I R R + +F R+D + + + +G+G VY+G +
Sbjct 656 IIKARSLRNASEAKAWRLTAFQRLDFTCDDVLDSLKEDNIIGKGGAGIVYKGTMPKGD-- 713
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAF 672
V +K L H + F + ++ H H+
Sbjct 714 -----------------------LVAVKRLATMSHGSSHDHGFNAEIQTLGRIRHRHIVR 750
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKN-- 729
+ G C N++V EY+ +G L L ++ GH+ + +A + A L YL +
Sbjct 751 LLGFCSNHETNLLVYEYMPNGSLGEVLHGKKGGHLHWNTRYKIALEAAKGLCYLHHDCSP 810
Query 730 -LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPE 782
+VH +V NILL ++ ++D G+ ++APE
Sbjct 811 LIVHRDVKSNNILLD-------SNFEAHVADFGLAKFLQDSGTSECMSAIAGSYGYIAPE 863
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAP-----------LQSRSPSEKEH------ 825
+ D + FG LLE+ G+ P RS ++
Sbjct 864 YA--YTLKVDEKSDVYSFGVVLLELI-TGKKPVGEFGDGVDIVQWVRSMTDSNKDCVLKV 920
Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
R +P + + C+ + +RP+ R +++ LT +
Sbjct 921 IDLRLSSVPVHEVTHVFYVALLCVEEQAVERPTMREVVQILTEIP 965
>sp|Q6PA14|STK4_XENLA Serine/threonine-protein kinase 4 OS=Xenopus
laevis OX=8355 GN=stk4 PE=2 SV=1
Length=485
Score = 228 bits (582), Expect = 8e-64, Method: Composition-based stats.
Identities = 63/270 (23%), Positives = 112/270 (41%), Gaps = 31/270 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V Y ++ T ++VA+K + + Q +EI I++ H++K
Sbjct 35 KLGEGSYGSV----YKASHKETSQIVAIKQIPVESDLQ---EIIKEISIMQQCDSPHVVK 87
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VME+ GS+ D L + ++ ++ Q +G+ YLH
Sbjct 88 YYGSYFKNTD--LWIVMEFCGGGSVSDIIRLRKQTLNEDEIATILQSTLKGLEYLHFMRK 145
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL + K+ DFG+A + + R FW APE ++E +
Sbjct 146 IHRDIKAGNILLSCEGTAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP--RP 1137
+D+WS G+T E+ ++ +R ++ +P
Sbjct 203 CVADIWSLGITAIEMAEGKPP---------------YAEIHPMRAIFMIPSNPPPTFRKP 247
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + + C R + L+
Sbjct 248 ELWSKDFVDFINLCLVKNPELRSSATELLQ 277
Score = 200 bits (508), Expect = 6e-54, Method: Composition-based stats.
Identities = 58/300 (19%), Positives = 99/300 (33%), Gaps = 44/300 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
LS+ S ++ ++ L LG+G+ +VY+ +
Sbjct 17 LSEESLNKQPEEVFDVLEKLGEGSYGSVYKASHKE------------------------T 52
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K + + S+M Q H+ +G + + +V E+ G +
Sbjct 53 SQIVAIKQIPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEFCGGGSV 110
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + + Q L YL +H ++ NILL+ G A
Sbjct 111 SDIIRLRKQTLNEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLSCEGTA------- 163
Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D GV R + W+APE + + D W G T +E+ +G
Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220
Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P P R PE + CL P R S +L+
Sbjct 221 KPPYAEIHPMRAIFMIPSNPPPTFRKPELWSKDFVDFINLCLVKNPELRSSATELLQHPF 280
>sp|Q8GX23|PERK5_ARATH Proline-rich receptor-like protein kinase
PERK5 OS=Arabidopsis thaliana OX=3702 GN=PERK5 PE=2 SV=1
Length=670
Score = 233 bits (595), Expect = 9e-64, Method: Composition-based stats.
Identities = 88/348 (25%), Positives = 135/348 (39%), Gaps = 31/348 (9%)
Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910
+P P P A L N + D + LG+G FG
Sbjct 266 QQPVSGPHSDASNLTGRTAIPSPQAATLGHNQSTFTYDELSIATEGFAQSNLLGQGGFGY 325
Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970
V +G+ VAVK+LK G R ++ E+DI+ ++H H++ G C G
Sbjct 326 VHKGVL-----PSGKEVAVKSLKLGSGQGERE-FQAEVDIISRVHHRHLVSLVGYCISGG 379
Query 971 EKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDL 1024
++ LV E++P +L +L R + + A G+AYLH IHRD+
Sbjct 380 QR--LLVYEFIPNNTLEFHLHGKGRPVLDWPTRVKIALGSARGLAYLHEDCHPRIIHRDI 437
Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084
A N+LLD K+ DFGLAK + + + R + APE K SDV
Sbjct 438 KAANILLDFSFETKVADFGLAKLSQDNYTHVSTR--VMGTFGYLAPEYASSGKLSDKSDV 495
Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG----QMTVLRLTELLERGERLPRPDKC 1140
+SFGV L EL+T L+ A+ +L + L +
Sbjct 496 FSFGVMLLELITGRPPLDLTGEMEDSLVDWARPLCLKAAQDGDYNQLADPRLELNYSHQ- 554
Query 1141 PCEVYHLMKNC----WETEASFRPTFENLIPILK---TVHEKYQGQAP 1181
E+ M +C A RP ++ L+ ++ + +G P
Sbjct 555 --EMVQ-MASCAAAAIRHSARRRPKMSQIVRALEGDMSMDDLSEGTRP 599
Score = 225 bits (574), Expect = 5e-61, Method: Composition-based stats.
Identities = 70/359 (19%), Positives = 120/359 (33%), Gaps = 61/359 (17%)
Query 488 AQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSL 547
++S + M + +G + + G +
Sbjct 216 KKKSPQVNHMHYYNNNPYGGAPSGNGGYYKGTPQDHVV----------NMAGQGGGNWGP 265
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNL----SQLSFHR--VDQKEITQLSHLGQGTRT 601
++ + SNL R A SP+ L S ++ + + Q + LGQG
Sbjct 266 QQPVSGPHSDASNLT-GRTAIPSPQAATLGHNQSTFTYDELSIATEGFAQSNLLGQGGFG 324
Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL 661
V++G L V +K L F +
Sbjct 325 YVHKGVLPSGK-------------------------EVAVKSLKLGSGQGEREFQAEVDI 359
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLAS 720
+S+V H HL + G C+ G + ++V E++ + L+ L + R + ++ +A A
Sbjct 360 ISRVHHRHLVSLVGYCISGGQRLLVYEFIPNNTLEFHLHGKGRPVLDWPTRVKIALGSAR 419
Query 721 ALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV---- 773
L+YL ++H ++ NILL S K++D G+ + V
Sbjct 420 GLAYLHEDCHPRIIHRDIKAANILLD-------FSFETKVADFGLAKLSQDNYTHVSTRV 472
Query 774 -ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
+LAPE G LS D + FG LLE+ G PL E +
Sbjct 473 MGTFGYLAPEYASSG--KLSDKSDVFSFGVMLLELI-TGRPPLDLTGEMEDSLVDWARP 528
>sp|O22834|LRK53_ARATH Probable L-type lectin-domain containing
receptor kinase V.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK53
PE=3 SV=1
Length=664
Score = 233 bits (594), Expect = 9e-64, Method: Composition-based stats.
Identities = 78/324 (24%), Positives = 123/324 (38%), Gaps = 21/324 (6%)
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920
+ + + + V + LGEG FG V + T
Sbjct 299 IVFFYKRHKKLLEVLEEWEVECGPHRFSYKELFNATNGFKQLLGEGGFGPV----FKGTL 354
Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
G+ +AVK + D R EI + L H ++++ G C + E L LV ++
Sbjct 355 SGSNAKIAVKRVSHDSSQGMRE-LLAEISTIGRLRHPNLVRLLGYCRYKEE--LYLVYDF 411
Query 981 VPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQHY---IHRDLAARNVLLDN 1033
+P GSL YL + + +Q + + ++YLH IHRD+ NVL+D+
Sbjct 412 LPNGSLDKYLYGTSDQKQLSWSQRFKIIKDVASALSYLHHGWIHVVIHRDIKPANVLIDD 471
Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
+GDFGLAK +G++ R G + APE ++ + +DV++FG+ + E
Sbjct 472 KMNASLGDFGLAKVYDQGYDPQTSRVAG--TFGYMAPEIMRTGRPTMGTDVYAFGMFMLE 529
Query 1094 LLTHCDSSQSPPTKFLE---LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
+ CD P E L A + E R V L
Sbjct 530 V--SCDRKLFEPRAESEEAILTNWAINCWENGDIVEAATERIRQDNDKGQLELVLKLGVL 587
Query 1151 CWETEASFRPTFENLIPILKTVHE 1174
C RP ++ IL V E
Sbjct 588 CSHEAEEVRPDMATVVKILNGVSE 611
Score = 207 bits (528), Expect = 4e-55, Method: Composition-based stats.
Identities = 46/263 (17%), Positives = 92/263 (35%), Gaps = 43/263 (16%)
Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
S+ + LG+G V++G L G +
Sbjct 325 FSYKELFNATNGFKQLLGEGGFGPVFKGTL------------------------SGSNAK 360
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+ +K + S + ++ H +L + G C E +V +++ +G LD +
Sbjct 361 IAVKRVSHDSSQGMRELLAEISTIGRLRHPNLVRLLGYCRYKEELYLVYDFLPNGSLDKY 420
Query 699 LR--RERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSP 753
L ++ + + + + + +ASALSYL + ++H ++ N+L+ A
Sbjct 421 LYGTSDQKQLSWSQRFKIIKDVASALSYLHHGWIHVVIHRDIKPANVLIDDKMNAS---- 476
Query 754 FIKLSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
L D G+ ++APE + G ++ T D + FG +LE+
Sbjct 477 ---LGDFGLAKVYDQGYDPQTSRVAGTFGYMAPEIMRTGRPTMGT--DVYAFGMFMLEVS 531
Query 809 FDGEAPLQSRSPSEKEHFYQRQH 831
D + E +
Sbjct 532 CDRKLFEPRAESEEAILTNWAIN 554
>sp|O04086|Y1105_ARATH Probable receptor-like protein kinase At1g11050
OS=Arabidopsis thaliana OX=3702 GN=At1g11050 PE=2 SV=1
Length=625
Score = 232 bits (592), Expect = 9e-64, Method: Composition-based stats.
Identities = 75/296 (25%), Positives = 122/296 (41%), Gaps = 28/296 (9%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+ +G G FG V G ++AVK + + Q + ++ E++I+ L
Sbjct 293 NNFSQKNFIGRGGFGFVYKGVL-----PDGSVIAVKKV-IESEFQGDAEFRNEVEIISNL 346
Query 955 YHEHIIKYKGC--CEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQLLLFAQQ 1006
H +++ +GC +D E LV +Y+ G+L D+L + + Q
Sbjct 347 KHRNLVPLRGCSMVDDDSESQRYLVYDYMSNGNLDDHLFPRGETTKMPLSWPQRKSIILD 406
Query 1007 ICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+ +G+AYLH HRD+ N+LLD D ++ DFGLAK EG + R G
Sbjct 407 VAKGLAYLHYGVKPAIYHRDIKGTNILLDVDMRARVADFGLAKQSREGESHLTTRVAG-- 464
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC---DSSQSPPTKFLELIGIAQGQMT 1120
+ APE + SDV+SFGV + E++ D S S + A +
Sbjct 465 THGYLAPEYALYGQLTEKSDVYSFGVVILEIMCGRKALDLSTSGSPNTFLITDWAWSLVK 524
Query 1121 VLRLTELLER------GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ E LE+ G L P + C + RPT + + +L+
Sbjct 525 AGKTEEALEQSLLREEGSGLSNPKGIMERFLQVGILCAHVLVALRPTILDALKMLE 580
Score = 201 bits (512), Expect = 2e-53, Method: Composition-based stats.
Identities = 60/296 (20%), Positives = 106/296 (36%), Gaps = 51/296 (17%)
Query 535 GCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL-SQLSFHRVDQKEITQLS 593
G L+ AG C R + GE + P T ++ ++ +Q +
Sbjct 240 GALVIAGLICLYFRFGKAVKGGEVGWEDQGSRPKWRPNTGSIWFKIEELEKATNNFSQKN 299
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
+G+G VY+G L + +K + S
Sbjct 300 FIGRGGFGFVYKGVLPDGS-------------------------VIAVKKVIESEFQGDA 334
Query 654 AFYETASLMSQVSHTHLAFVHGVCV----RGPENIMVTEYVEHGPLDVWL--RRERGHVP 707
F ++S + H +L + G + + +V +Y+ +G LD L R E +P
Sbjct 335 EFRNEVEIISNLKHRNLVPLRGCSMVDDDSESQRYLVYDYMSNGNLDDHLFPRGETTKMP 394
Query 708 MAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
++W + + +A L+YL + H ++ G NILL +++D G+
Sbjct 395 LSWPQRKSIILDVAKGLAYLHYGVKPAIYHRDIKGTNILLD-------VDMRARVADFGL 447
Query 763 GLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
+ E +LAPE G L+ D + FG +LEI +A
Sbjct 448 AKQSREGESHLTTRVAGTHGYLAPEYALYG--QLTEKSDVYSFGVVILEIMCGRKA 501
>sp|Q9LPZ3|Y1141_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g11410 OS=Arabidopsis thaliana OX=3702
GN=At1g11410 PE=3 SV=3
Length=845
Score = 237 bits (604), Expect = 1e-63, Method: Composition-based stats.
Identities = 77/283 (27%), Positives = 125/283 (44%), Gaps = 18/283 (6%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
LG G FG V G +AVK L G Q +K E+ ++ L
Sbjct 521 NNFAFQNKLGAGGFGPVYKGVLQ-----NGMEIAVKRLSKSSG-QGMEEFKNEVKLISKL 574
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEG 1010
H ++++ GCC + EK LV EY+P SL ++ R + + + + I G
Sbjct 575 QHRNLVRILGCCVEFEEK--MLVYEYLPNKSLDYFIFHEEQRAELDWPKRMGIIRGIGRG 632
Query 1011 MAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH IHRDL A NVLLDN+ + KI DFGLA+ G++ +
Sbjct 633 ILYLHQDSRLRIIHRDLKASNVLLDNEMIPKIADFGLARIFG-GNQIEGSTNRVVGTYGY 691
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
+PE + +F SDV+SFGV + E++T +S + L L+ + E+
Sbjct 692 MSPEYAMDGQFSIKSDVYSFGVLILEIITGKRNSAF-YEESLNLVKHIWDRWENGEAIEI 750
Query 1128 LERGE-RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+++ + + H+ C + +S RP +++ +L
Sbjct 751 IDKLMGEETYDEGEVMKCLHIGLLCVQENSSDRPDMSSVVFML 793
Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats.
Identities = 61/370 (16%), Positives = 113/370 (31%), Gaps = 61/370 (16%)
Query 557 ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616
E S ++ ++ R L L +LS + LG G VY+G L+
Sbjct 491 EDSFILEELEDKSRSRELPLFELSTIATATNNFAFQNKLGAGGFGPVYKGVLQNG----- 545
Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676
+ + +K L S F L+S++ H +L + G
Sbjct 546 --------------------MEIAVKRLSKSSGQGMEEFKNEVKLISKLQHRNLVRILGC 585
Query 677 CVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLV 731
CV E ++V EY+ + LD ++ E + W +M + + + + YL ++
Sbjct 586 CVEFEEKMLVYEYLPNKSLDYFIFHEEQRAELDWPKRMGIIRGIGRGILYLHQDSRLRII 645
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP 785
H ++ N+LL + K++D G+ S V +++PE
Sbjct 646 HRDLKASNVLLDNEMIP-------KIADFGLARIFGGNQIEGSTNRVVGTYGYMSPEYAM 698
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEA-------------PLQSRSPSEKEHFYQRQH- 831
G S D + FG +LEI E +
Sbjct 699 DG--QFSIKSDVYSFGVLILEIITGKRNSAFYEESLNLVKHIWDRWENGEAIEIIDKLMG 756
Query 832 --RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
E + + C+ + RP +++ L + +
Sbjct 757 EETYDEGEVMKCLHIGLLCVQENSSDRPDMSSVVFMLGHNAIDLPSPKHPAFTAGRRRNT 816
Query 890 TVFHKRYLKK 899
Sbjct 817 KTGGSSDNWP 826
>sp|B9DFG5|PTI13_ARATH PTI1-like tyrosine-protein kinase 3 OS=Arabidopsis
thaliana OX=3702 GN=PTI13 PE=1 SV=1
Length=408
Score = 226 bits (575), Expect = 1e-63, Method: Composition-based stats.
Identities = 74/356 (21%), Positives = 125/356 (35%), Gaps = 35/356 (10%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV------------ 891
L C EP + + A
Sbjct 47 LCCACHVEEPYHSSENEHLRSPKHHNDFGHHTRKPQAAVKPDALKEPPSIDVPALSLDEL 106
Query 892 -FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+GEG +G+ G+ VAVK L P+ + ++
Sbjct 107 KEKTDNFGSKSLIGEGSYGRAYYATLK-----DGKAVAVKKLDNAAEPESNVEFLTQVSR 161
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------IGLAQL 1000
+ L H++ ++ G C + + L E+ +GSL D L + Q
Sbjct 162 VSKLKHDNFVELFGYCVEGNFRILA--YEFATMGSLHDILHGRKGVQGAQPGPTLDWIQR 219
Query 1001 LLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ A G+ YLH + IHRD+ + NVLL D KI DF L+ P+
Sbjct 220 VRIAVDAARGLEYLHEKVQPAVIHRDIRSSNVLLFEDFKAKIADFNLSNQSPD-MAARLH 278
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQ 1116
++APE + SDV+SFGV L ELLT + P L+ A
Sbjct 279 STRVLGTFGYHAPEYAMTGQLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWAT 338
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+++ ++ + ++ + P K ++ + C + E+ FRP ++ L+ +
Sbjct 339 PRLSEDKVKQCVDPKLKGEYPPKAVAKLAAVAALCVQYESEFRPNMSIVVKALQPL 394
Score = 190 bits (482), Expect = 2e-51, Method: Composition-based stats.
Identities = 55/306 (18%), Positives = 98/306 (32%), Gaps = 54/306 (18%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615
+ A P ++++ LS + S +G+G+ Y L+
Sbjct 80 KPQAAVKPDALKEPPSIDVPALSLDELKEKTDNFGSKSLIGEGSYGRAYYATLKDGK--- 136
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVH 674
V +K LD + + + F S +S++ H + +
Sbjct 137 ----------------------AVAVKKLDNAAEPESNVEFLTQVSRVSKLKHDNFVELF 174
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERG--------HVPMAWKMVVAQQLASALSYLE 726
G CV G I+ E+ G L L +G + ++ +A A L YL
Sbjct 175 GYCVEGNFRILAYEFATMGSLHDILHGRKGVQGAQPGPTLDWIQRVRIAVDAARGLEYLH 234
Query 727 NK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG------LGALSREERVERIP 777
K ++H ++ N+LL K++D + L +
Sbjct 235 EKVQPAVIHRDIRSSNVLLFE-------DFKAKIADFNLSNQSPDMAARLHSTRVLGTFG 287
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS 837
+ APE G L+ D + FG LLE+ + + ++ RL E
Sbjct 288 YHAPEYAMTG--QLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRLSEDK 345
Query 838 CPQLAT 843
Q
Sbjct 346 VKQCVD 351
>sp|Q5R5M7|RAF1_PONAB RAF proto-oncogene serine/threonine-protein
kinase OS=Pongo abelii OX=9601 GN=RAF1 PE=2 SV=1
Length=648
Score = 233 bits (593), Expect = 1e-63, Method: Composition-based stats.
Identities = 80/333 (24%), Positives = 136/333 (41%), Gaps = 35/333 (11%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
+ T P+ R + + + +S + +G G F
Sbjct 305 WSQPKTPVPAQRE----RAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF 360
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
G V + VAVK LK D P+ ++ E+ +LR H +I+ + G
Sbjct 361 GTVYKGKWHG-------DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYM- 412
Query 968 DQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
+ +L +V ++ SL +L + QL+ A+Q +GM YLHA++ IHRD+
Sbjct 413 --TKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMK 470
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYAS 1082
+ N+ L VKIGDFGLA +V E V W APE ++ F + S
Sbjct 471 SNNIFLHEGLTVKIGDFGLATVKSRWSGSQQV-EQPTGSVLWMAPEVIRMQDNNPFSFQS 529
Query 1083 DVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
DV+S+G+ LYEL+T + + ++G + +L + C
Sbjct 530 DVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYK------------NC 577
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
P + L+ +C + RP F ++ ++ +
Sbjct 578 PKAMKRLVADCVKKVKEERPLFPQILSSIELLQ 610
Score = 220 bits (561), Expect = 1e-59, Method: Composition-based stats.
Identities = 69/367 (19%), Positives = 126/367 (34%), Gaps = 62/367 (17%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
R + N I RG R S + ++ E+ + +G G+ VY+G+
Sbjct 316 RERAPVSGTQEKNKIRPRGQRDSSY--------YWEIEASEVMLSTRIGSGSFGTVYKGK 367
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQ 664
+ V +K+L DP+ AF +++ +
Sbjct 368 WHGD---------------------------VAVKILKVVDPTPEQFQ-AFRNEVAVLRK 399
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
H ++ G + +VT++ E L L + M + +A+Q A + Y
Sbjct 400 TRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778
L KN++H ++ NI L +K+ D G+ G+ E+ + W
Sbjct 459 LHAKNIIHRDMKSNNIFLHEGL-------TVKIGDFGLATVKSRWSGSQQVEQPTGSVLW 511
Query 779 LAPECLPGGA-NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------ 831
+APE + N S D + +G L E+ GE P + ++ F +
Sbjct 512 MAPEVIRMQDNNPFSFQSDVYSYGIVLYELM-TGELPYSHINNRDQIIFMVGRGYASPDL 570
Query 832 -RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
+L + + L + C+ +RP F IL + LQ + + S
Sbjct 571 SKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAH 630
Query 891 VFHKRYL 897
Sbjct 631 TEDINAC 637
>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein
kinase OS=Homo sapiens OX=9606 GN=RAF1 PE=1 SV=1
Length=648
Score = 233 bits (593), Expect = 1e-63, Method: Composition-based stats.
Identities = 80/333 (24%), Positives = 136/333 (41%), Gaps = 35/333 (11%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
+ T P+ R + + + +S + +G G F
Sbjct 305 WSQPKTPVPAQRE----RAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF 360
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
G V + VAVK LK D P+ ++ E+ +LR H +I+ + G
Sbjct 361 GTVYKGKWHG-------DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYM- 412
Query 968 DQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
+ +L +V ++ SL +L + QL+ A+Q +GM YLHA++ IHRD+
Sbjct 413 --TKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMK 470
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYAS 1082
+ N+ L VKIGDFGLA +V E V W APE ++ F + S
Sbjct 471 SNNIFLHEGLTVKIGDFGLATVKSRWSGSQQV-EQPTGSVLWMAPEVIRMQDNNPFSFQS 529
Query 1083 DVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
DV+S+G+ LYEL+T + + ++G + +L + C
Sbjct 530 DVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYK------------NC 577
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
P + L+ +C + RP F ++ ++ +
Sbjct 578 PKAMKRLVADCVKKVKEERPLFPQILSSIELLQ 610
Score = 220 bits (561), Expect = 1e-59, Method: Composition-based stats.
Identities = 69/367 (19%), Positives = 126/367 (34%), Gaps = 62/367 (17%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
R + N I RG R S + ++ E+ + +G G+ VY+G+
Sbjct 316 RERAPVSGTQEKNKIRPRGQRDSSY--------YWEIEASEVMLSTRIGSGSFGTVYKGK 367
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQ 664
+ V +K+L DP+ AF +++ +
Sbjct 368 WHGD---------------------------VAVKILKVVDPTPEQFQ-AFRNEVAVLRK 399
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
H ++ G + +VT++ E L L + M + +A+Q A + Y
Sbjct 400 TRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778
L KN++H ++ NI L +K+ D G+ G+ E+ + W
Sbjct 459 LHAKNIIHRDMKSNNIFLHEGL-------TVKIGDFGLATVKSRWSGSQQVEQPTGSVLW 511
Query 779 LAPECLPGGA-NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------ 831
+APE + N S D + +G L E+ GE P + ++ F +
Sbjct 512 MAPEVIRMQDNNPFSFQSDVYSYGIVLYELM-TGELPYSHINNRDQIIFMVGRGYASPDL 570
Query 832 -RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
+L + + L + C+ +RP F IL + LQ + + S
Sbjct 571 SKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAH 630
Query 891 VFHKRYL 897
Sbjct 631 TEDINAC 637
>sp|O64483|SIRK_ARATH Senescence-induced receptor-like serine/threonine-protein
kinase OS=Arabidopsis thaliana OX=3702 GN=SIRK
PE=1 SV=1
Length=876
Score = 237 bits (605), Expect = 1e-63, Method: Composition-based stats.
Identities = 65/294 (22%), Positives = 122/294 (41%), Gaps = 16/294 (5%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
+ R +G+G FGKV GE VAVK L + Q +
Sbjct 562 RYFKYSEVVNITNNFERVIGKGGFGKVYHGVI------NGEQVAVKVLSEE-SAQGYKEF 614
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLL 1001
+ E+D+L ++H ++ G C + + L+ EY+ +L DYL + + L
Sbjct 615 RAEVDLLMRVHHTNLTSLVGYCNEINH--MVLIYEYMANENLGDYLAGKRSFILSWEERL 672
Query 1002 LFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
+ +G+ YLH +HRD+ N+LL+ K+ DFGL+++ ++
Sbjct 673 KISLDAAQGLEYLHNGCKPPIVHRDVKPTNILLNEKLQAKMADFGLSRSFSV-EGSGQIS 731
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
+ + PE + SDV+S GV L E++T + S T+ + + +
Sbjct 732 TVVAGSIGYLDPEYYSTRQMNEKSDVYSLGVVLLEVITGQPAIASSKTEKVHISDHVRSI 791
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ + ++++ R ++ + C E ++ RPT ++ LK +
Sbjct 792 LANGDIRGIVDQRLRERYDVGSAWKMSEIALACTEHTSAQRPTMSQVVMELKQI 845
Score = 202 bits (514), Expect = 4e-52, Method: Composition-based stats.
Identities = 66/349 (19%), Positives = 114/349 (33%), Gaps = 65/349 (19%)
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
G R P + V +G+G VY G + E
Sbjct 551 GERNGPLKTAKRYFKYSEVVNITNNFERVIGKGGFGKVYHGVINGE-------------- 596
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
+V +KVL F L+ +V HT+L + G C ++
Sbjct 597 ------------QVAVKVLSEESAQGYKEFRAEVDLLMRVHHTNLTSLVGYCNEINHMVL 644
Query 686 VTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNIL 741
+ EY+ + L +L +R + ++ ++ A L YL N +VH +V NIL
Sbjct 645 IYEYMANENLGDYLAGKRSFILSWEERLKISLDAAQGLEYLHNGCKPPIVHRDVKPTNIL 704
Query 742 LARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAM 795
L A K++D G+ I +L PE ++
Sbjct 705 LNEKLQA-------KMADFGLSRSFSVEGSGQISTVVAGSIGYLDPEYYST--RQMNEKS 755
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR--------------QHRLPEPSCP-- 839
D + G LLE+ P + S +EK H RL E
Sbjct 756 DVYSLGVVLLEVITG--QPAIASSKTEKVHISDHVRSILANGDIRGIVDQRLRERYDVGS 813
Query 840 --QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
+++ + C + QRP+ ++ +L ++ + D + +
Sbjct 814 AWKMSEIALACTEHTSAQRPTMSQVVMELKQIVYGIVTDQENYDDSTKM 862
>sp|Q9M0G5|CRK46_ARATH Cysteine-rich receptor-like protein kinase
46 OS=Arabidopsis thaliana OX=3702 GN=CRK46 PE=3 SV=1
Length=625
Score = 232 bits (591), Expect = 1e-63, Method: Composition-based stats.
Identities = 69/316 (22%), Positives = 123/316 (39%), Gaps = 18/316 (6%)
Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE 925
R++ + + + S + LG G +G+V G
Sbjct 300 HLRIEKESESICTESHLMSFEYSTLKKATNNFNESCKLGVGGYGEVFKGTL-----SDGR 354
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
+A+K L G + R EID++ H+++++ GCC +V E++ S
Sbjct 355 EIAIKRLHV-SGKKPRDEIHNEIDVISRCQHKNLVRLLGCCFTNMNS--FIVYEFLANTS 411
Query 986 LRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA-QHYIHRDLAARNVLLDNDRLVKIG 1040
L L + + + EG+ YLH IHRD+ A N+LLD KI
Sbjct 412 LDHILFNPEKKKELDWKKRRTIILGTAEGLEYLHETCKIIHRDIKASNILLDLKYKPKIS 471
Query 1041 DFGLAKAVPEGHE----YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
DFGLAK PEG + + + APE + + + D +SFGV + E+ +
Sbjct 472 DFGLAKFYPEGGKDIPASSLSPSSIAGTLGYMAPEYISKGRLSNKIDAYSFGVLVLEITS 531
Query 1097 HCDSSQSPPTKFLE-LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155
+++ LE L+ ++ E++++ + V + C +
Sbjct 532 GFRNNKFRSDNSLETLVTQVWKCFASNKMEEMIDKDMGEDTDKQEMKRVMQIGLLCTQES 591
Query 1156 ASFRPTFENLIPILKT 1171
RPT +I ++ +
Sbjct 592 PQLRPTMSKVIQMVSS 607
Score = 204 bits (518), Expect = 4e-54, Method: Composition-based stats.
Identities = 54/325 (17%), Positives = 100/325 (31%), Gaps = 65/325 (20%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
L + S + + LG G V++G L
Sbjct 314 SHLMSFEYSTLKKATNNFNESCKLGVGGYGEVFKGTLSDGR------------------- 354
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+ +K L S + ++S+ H +L + G C + +V E++
Sbjct 355 ------EIAIKRLHVSGKKPRDEIHNEIDVISRCQHKNLVRLLGCCFTNMNSFIVYEFLA 408
Query 692 HGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK-NLVHGNVCGRNILLARLGLA 748
+ LD L + W + + A L YL ++H ++ NILL
Sbjct 409 NTSLDHILFNPEKKKELDWKKRRTIILGTAEGLEYLHETCKIIHRDIKASNILLD----- 463
Query 749 EGTSPFIKLSDPGVGL-----------GALSREERVERIPWLAPECLPGGANSLSTAMDK 797
K+SD G+ +LS + ++APE + G LS +D
Sbjct 464 --LKYKPKISDFGLAKFYPEGGKDIPASSLSPSSIAGTLGYMAPEYISKG--RLSNKIDA 519
Query 798 WGFGATLLEI-----------------CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840
+ FG +LEI + + E+ + +
Sbjct 520 YSFGVLVLEITSGFRNNKFRSDNSLETLVTQVWKCFASNKMEEMIDKDMGEDTDKQEMKR 579
Query 841 LATLTSQCLTYEPTQRPSFRTILRD 865
+ + C P RP+ +++
Sbjct 580 VMQIGLLCTQESPQLRPTMSKVIQM 604
>sp|Q55EI8|Y9956_DICDI Probable serine/threonine-protein kinase
DDB_G0268876 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0268876
PE=3 SV=1
Length=1385
Score = 241 bits (615), Expect = 1e-63, Method: Composition-based stats.
Identities = 79/281 (28%), Positives = 128/281 (46%), Gaps = 31/281 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
++G G G V + G +AVK + + E I+ L H++I+
Sbjct 763 EIGRGVSGVVKRGKWK------GYEIAVKQFNEEELGFSEREFHSEATIMSVLRHDNIVH 816
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHY 1019
G G+ + LV +Y GSL + + + A+++ A Q+ +GM YLH+
Sbjct 817 CVGGSAQPGK--MYLVCDYYSRGSLYSVITANICPLSNARIVHLALQVAKGMNYLHSLGI 874
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
IHRDL N+L+D D ++I DFGL++ V R+ + +P + A E LK +
Sbjct 875 IHRDLKPGNLLIDQDWNIRISDFGLSRVVDN-----RMTKTVGTPC-YMAVEVLKGLTDY 928
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+DV+SF L+E ++ Q P F ++ I+ +LE R P PD
Sbjct 929 SQQADVYSFAFVLWECISR----QIPYKDFAQIQWISM----------VLEDSFRPPIPD 974
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
C E L+ CW + RP+F+ +I L+ + K Q Q
Sbjct 975 SCLPEFRDLITMCWTSNPDDRPSFQQIITYLENLRLKMQDQ 1015
Score = 202 bits (515), Expect = 2e-51, Method: Composition-based stats.
Identities = 54/305 (18%), Positives = 110/305 (36%), Gaps = 40/305 (13%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
+ Q ++ +G+G V G+ + +
Sbjct 750 LKYISQSDLELTKEIGRGVSGVVKRGKWKG--------------------------YEIA 783
Query 641 LKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+K + F+ A++MS + H ++ G + + +V +Y G L +
Sbjct 784 VKQFNEEELGFSEREFHSEATIMSVLRHDNIVHCVGGSAQPGKMYLVCDYYSRGSLYSVI 843
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ A + +A Q+A ++YL + ++H ++ N+L+ + I++SD
Sbjct 844 TANICPLSNARIVHLALQVAKGMNYLHSLGIIHRDLKPGNLLIDQ-------DWNIRISD 896
Query 760 PGVGLGALSR-EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
G+ +R + V ++A E L G S D + F L E + P +
Sbjct 897 FGLSRVVDNRMTKTVGTPCYMAVEVLK-GLTDYSQQADVYSFAFVLWECISR-QIPYKDF 954
Query 819 SPSEKEHF---YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ + + +P+ P+ L + C T P RPSF+ I+ L L+
Sbjct 955 AQIQWISMVLEDSFRPPIPDSCLPEFRDLITMCWTSNPDDRPSFQQIITYLENLRLKMQD 1014
Query 876 DVLTV 880
+
Sbjct 1015 QGIYQ 1019
>sp|Q9LFG1|Y3359_ARATH Putative leucine-rich repeat receptor-like
serine/threonine-protein kinase At3g53590 OS=Arabidopsis
thaliana OX=3702 GN=At3g53590 PE=1 SV=2
Length=937
Score = 238 bits (607), Expect = 1e-63, Method: Composition-based stats.
Identities = 77/293 (26%), Positives = 121/293 (41%), Gaps = 25/293 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G +GKV VA+K + Q + EID+L L+H +++
Sbjct 620 IGRGSYGKVYKGIL-----SNKTEVAIKR-GEETSLQSEKEFLNEIDLLSRLHHRNLVSL 673
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLH---A 1016
G D GE+ LV EY+P G++RD+L + ++ + A +G+ YLH
Sbjct 674 IGYSSDIGEQ--MLVYEYMPNGNVRDWLSANAADTLSFSMRSHVALGSAKGILYLHTEAN 731
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE----GHEYYRVREDGDSPVFWYAPEC 1072
IHRD+ N+LLD K+ DFGL++ P E V + PE
Sbjct 732 PPVIHRDIKTSNILLDCQLHAKVADFGLSRLAPAFGEGDGEPAHVSTVVRGTPGYLDPEY 791
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ SDV+SFGV L ELLT P + +I + + + +
Sbjct 792 FMTQQLTVRSDVYSFGVVLLELLTGM----HPFFEGTHIIREVRTANECGTVLSVADSRM 847
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
PDK ++ L C E RP ++ L+ + + + P +FS
Sbjct 848 GQCSPDKV-KKLAELALWCCEDRPETRPPMSKVVKELEGICQSVR--EPEMFS 897
Score = 202 bits (514), Expect = 5e-52, Method: Composition-based stats.
Identities = 67/385 (17%), Positives = 119/385 (31%), Gaps = 65/385 (17%)
Query 553 PQPGETSNLIIMRGARASPRTL-NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLR 609
+ + L R R R + + + SF + + +G+G+ VY+G L
Sbjct 575 KRRENSHTLTKKRVFRTISREIKGVKKFSFVELSDATNGFDSSTLIGRGSYGKVYKGIL- 633
Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTH 669
+ V +K + + F L+S++ H +
Sbjct 634 ------------------------SNKTEVAIKRGEETSLQSEKEFLNEIDLLSRLHHRN 669
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLE-- 726
L + G E ++V EY+ +G + WL + + + VA A + YL
Sbjct 670 LVSLIGYSSDIGEQMLVYEYMPNGNVRDWLSANAADTLSFSMRSHVALGSAKGILYLHTE 729
Query 727 -NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS-----------REERVE 774
N ++H ++ NILL K++D G+ A +
Sbjct 730 ANPPVIHRDIKTSNILLD-------CQLHAKVADFGLSRLAPAFGEGDGEPAHVSTVVRG 782
Query 775 RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP--SEKEHFYQ---- 828
+L PE L+ D + FG LLE+ G P + E +
Sbjct 783 TPGYLDPEYFMT--QQLTVRSDVYSFGVVLLELL-TGMHPFFEGTHIIREVRTANECGTV 839
Query 829 ------RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
R + +LA L C P RP ++++L + +
Sbjct 840 LSVADSRMGQCSPDKVKKLAELALWCCEDRPETRPPMSKVVKELEGICQSVREPEMFSET 899
Query 883 DSPASDPTVFHKRYLKKIRDLGEGH 907
T + L G
Sbjct 900 TKLLCSKTSPSSSSVPSPLSLLPGS 924
>sp|Q9LSL5|LRK92_ARATH L-type lectin-domain containing receptor
kinase IX.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK92 PE=1
SV=1
Length=675
Score = 233 bits (594), Expect = 1e-63, Method: Composition-based stats.
Identities = 80/326 (25%), Positives = 127/326 (39%), Gaps = 24/326 (7%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
R + RD+ + N P + V R LGEG FG V
Sbjct 307 WSRKQRKKKERDIENMISINKDLEREAGPRKFSYKDLVSATNRFSSHRKLGEGGFGAVYE 366
Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
N MVAVK L D Q ++ + E+ I+ L H ++++ G C ++ E
Sbjct 367 GNLKEIN----TMVAVKKLSGD-SRQGKNEFLNEVKIISKLRHRNLVQLIGWCNEKNE-- 419
Query 974 LQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAAR 1027
L+ E VP GSL +L + + + YLH Q +HRD+ A
Sbjct 420 FLLIYELVPNGSLNSHLFGKRPNLLSWDIRYKIGLGLASALLYLHEEWDQCVLHRDIKAS 479
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
N++LD++ VK+GDFGLA+ + HE + APE + + SD++SF
Sbjct 480 NIMLDSEFNVKLGDFGLARLM--NHELGSHTTGLAGTFGYMAPEYVMKGSASKESDIYSF 537
Query 1088 GVTLYELLTHC--------DSSQSPPTKFLELIGIAQGQMTVLRL-TELLERGERLPRPD 1138
G+ L E++T D+S + L+ L T ++
Sbjct 538 GIVLLEIVTGRKSLERTQEDNSDTESDDEKSLVEKVWELYGKQELITSCVDDKLGEDFDK 597
Query 1139 KCPCEVYHLMKNCWETEASFRPTFEN 1164
K + L C + + RP+ +
Sbjct 598 KEAECLLVLGLWCAHPDKNSRPSIKQ 623
Score = 228 bits (582), Expect = 5e-62, Method: Composition-based stats.
Identities = 58/289 (20%), Positives = 102/289 (35%), Gaps = 48/289 (17%)
Query 537 LLRAGDDCFSLRRCCLPQPGETSNLIIMRGA---RASPRTLNLSQLSFHRVDQKEITQLS 593
+ R+ + + N+I + A PR + L +
Sbjct 298 FMVITTVVVWSRKQRKKKERDIENMISINKDLEREAGPRKFSYKDLVS---ATNRFSSHR 354
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LG+G VYEG L+ + V +K L
Sbjct 355 KLGEGGFGAVYEGNLKEINTM------------------------VAVKKLSGDSRQGKN 390
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKM 712
F ++S++ H +L + G C E +++ E V +G L+ L +R + + +
Sbjct 391 EFLNEVKIISKLRHRNLVQLIGWCNEKNEFLLIYELVPNGSLNSHLFGKRPNLLSWDIRY 450
Query 713 VVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----- 764
+ LASAL YL + ++H ++ NI+L + +KL D G+
Sbjct 451 KIGLGLASALLYLHEEWDQCVLHRDIKASNIMLD-------SEFNVKLGDFGLARLMNHE 503
Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
++APE + G+ S D + FG LLEI ++
Sbjct 504 LGSHTTGLAGTFGYMAPEYVMKGSA--SKESDIYSFGIVLLEIVTGRKS 550
>sp|Q9FLW0|Y5241_ARATH Probable receptor-like protein kinase At5g24010
OS=Arabidopsis thaliana OX=3702 GN=At5g24010 PE=1 SV=1
Length=824
Score = 236 bits (602), Expect = 1e-63, Method: Composition-based stats.
Identities = 76/285 (27%), Positives = 122/285 (43%), Gaps = 20/285 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V VAVK + Q + EI IL + H H++
Sbjct 495 IGVGGFGMVFRGSLK-----DNTKVAVKR-GSPGSRQGLPEFLSEITILSKIRHRHLVSL 548
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH---A 1016
G CE+Q E + LV EY+ G L+ +L + Q L G+ YLH +
Sbjct 549 VGYCEEQSE--MILVYEYMDKGPLKSHLYGSTNPPLSWKQRLEVCIGAARGLHYLHTGSS 606
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
Q IHRD+ + N+LLDN+ + K+ DFGL+++ P E + V + PE +
Sbjct 607 QGIIHRDIKSTNILLDNNYVAKVADFGLSRSGPCIDETH-VSTGVKGSFGYLDPEYFRRQ 665
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR---LTELLERGER 1133
+ SDV+SFGV L+E+L C P E + +A+ + R L ++++
Sbjct 666 QLTDKSDVYSFGVVLFEVL--CARPAVDPLLVREQVNLAEWAIEWQRKGMLDQIVDPNIA 723
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
+ + C RPT +++ L+ V + +
Sbjct 724 DEIKPCSLKKFAETAEKCCADYGVDRPTIGDVLWNLEHVLQLQES 768
Score = 220 bits (560), Expect = 3e-58, Method: Composition-based stats.
Identities = 66/335 (20%), Positives = 113/335 (34%), Gaps = 64/335 (19%)
Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASP------RTLNLSQLSFHRVD-------QKEI 589
C R+ + E++ +R R S RT++ S R+
Sbjct 430 LCLCRRKNNKTRSSESTGWTPLRRFRGSSNSRTTERTVSSSGYHTLRISFAELQSGTNNF 489
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
+ +G G V+ G L+ +V +K P
Sbjct 490 DRSLVIGVGGFGMVFRGSLKDN-------------------------TKVAVKRGSPGSR 524
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPM 708
F +++S++ H HL + G C E I+V EY++ GPL L +
Sbjct 525 QGLPEFLSEITILSKIRHRHLVSLVGYCEEQSEMILVYEYMDKGPLKSHLYGSTNPPLSW 584
Query 709 AWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL- 764
++ V A L YL ++ ++H ++ NILL + K++D G+
Sbjct 585 KQRLEVCIGAARGLHYLHTGSSQGIIHRDIKSTNILLDN-------NYVAKVADFGLSRS 637
Query 765 GALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
G E V +L PE L+ D + FG L E+ +
Sbjct 638 GPCIDETHVSTGVKGSFGYLDPEYFR--RQQLTDKSDVYSFGVVLFEVLC-ARPAVDPLL 694
Query 820 PSEKEHF------YQRQHRLPEPSCPQLATLTSQC 848
E+ + +QR+ L + P +A C
Sbjct 695 VREQVNLAEWAIEWQRKGMLDQIVDPNIADEIKPC 729
>sp|Q54R82|MKKA_DICDI Mitogen-activated protein kinase kinase
kinase A OS=Dictyostelium discoideum OX=44689 GN=mkkA PE=1 SV=2
Length=942
Score = 238 bits (606), Expect = 1e-63, Method: Composition-based stats.
Identities = 76/301 (25%), Positives = 136/301 (45%), Gaps = 29/301 (10%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL- 932
+ + H +K + LG G +G V L N TGE+ AVK L
Sbjct 147 QHTDFPSLIINEHEELISNHNIKWQKGQILGRGGYGSVYLG----LNKDTGELFAVKQLE 202
Query 933 --KADCGPQHRS---GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
+ P+ ++ + +EI+++R+L H++I++Y G DQ S+ L EY+P GS+
Sbjct 203 IVDINSDPKLKNMILSFSKEIEVMRSLRHDNIVRYLGTSLDQSFLSVFL--EYIPGGSIS 260
Query 988 DYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
L + + ++ +QI +G+++LHA IHRD+ N+L+D +VK+ DFG +K
Sbjct 261 SLLGKFGAFSENVIKVYTKQILQGLSFLHANSIIHRDIKGANILIDTKGIVKLSDFGCSK 320
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
+ ++ + +W APE +K+ +SD+WS G + E+ T +Q P +
Sbjct 321 SFSGIVSQFKSMQ---GTPYWMAPEVIKQTGHGRSSDIWSLGCVIVEMAT----AQPPWS 373
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
EL + + + P E + + C++ + RP L+
Sbjct 374 NITELAAVMYHIASSNSIPN---------IPSHMSQEAFDFLNLCFKRDPKERPDANQLL 424
Query 1167 P 1167
Sbjct 425 K 425
Score = 190 bits (482), Expect = 5e-48, Method: Composition-based stats.
Identities = 55/307 (18%), Positives = 107/307 (35%), Gaps = 53/307 (17%)
Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
+S H + + + LG+G +VY G + G
Sbjct 163 ISNHNIKWQ---KGQILGRGGYGSVYLGLNKDTGELF----------------------- 196
Query 639 VVLKVL-------DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+K L DP ++ L+F + +M + H ++ G + + EY+
Sbjct 197 -AVKQLEIVDINSDPKLKNMILSFSKEIEVMRSLRHDNIVRYLGTSLDQSFLSVFLEYIP 255
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G + L + G V +Q+ LS+L +++H ++ G NIL+ G+
Sbjct 256 GGSISSLL-GKFGAFSENVIKVYTKQILQGLSFLHANSIIHRDIKGANILIDTKGI---- 310
Query 752 SPFIKLSDPGVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+KLSD G + W+APE + + S D W G ++E+
Sbjct 311 ---VKLSDFGCSKSFSGIVSQFKSMQGTPYWMAPEVIKQTGHGRS--SDIWSLGCVIVEM 365
Query 808 CFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
+ P + + ++ +P + + C +P +RP +L
Sbjct 366 A-TAQPPWSNITELAAVMYHIASSNSIPNIPSHMSQEAFDFLNLCFKRDPKERPDANQLL 424
Query 864 RDLTRLQ 870
+ +
Sbjct 425 KHPFIMN 431
>sp|Q9STV4|CIPK8_ARATH CBL-interacting serine/threonine-protein
kinase 8 OS=Arabidopsis thaliana OX=3702 GN=CIPK8 PE=1 SV=1
Length=445
Score = 226 bits (577), Expect = 1e-63, Method: Composition-based stats.
Identities = 63/268 (24%), Positives = 111/268 (41%), Gaps = 29/268 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959
+GEG F KV N TGE VA+K + + + K+EI I++ + H +
Sbjct 14 TIGEGTFAKVKF----AQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLVRHPCV 69
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018
++ + + + +++EY+ G L D + R+ + ++ + Q+ +G+ Y H++
Sbjct 70 VRLYEVLASRTK--IYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDYCHSKG 127
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N+LLD+ +KI DFGL+ +G + + APE L +
Sbjct 128 VYHRDLKPENLLLDSQGNLKISDFGLSALPEQGVTILKTT---CGTPNYVAPEVLSHKGY 184
Query 1079 YYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
A D+WS GV LY L+ +M + L +++ E P
Sbjct 185 NGAVADIWSCGVILYVLMAGYLPFD---------------EMDLPTLYSKIDKAE-FSCP 228
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165
L+ + R T +
Sbjct 229 SYFALGAKSLINRILDPNPETRITIAEI 256
Score = 175 bits (443), Expect = 7e-46, Method: Composition-based stats.
Identities = 53/321 (17%), Positives = 101/321 (31%), Gaps = 42/321 (13%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ +G+GT V ++ V +K++D S
Sbjct 8 KYELGRTIGEGTFAKV------------------------KFAQNTETGESVAMKIVDRS 43
Query 648 ---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ S+M V H + ++ V + ++ EY+ G L + R G
Sbjct 44 TIIKRKMVDQIKREISIMKLVRHPCVVRLYEVLASRTKIYIILEYITGGELFDKIVRN-G 102
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763
+ + QL + Y +K + H ++ N+LL G +K+SD G+
Sbjct 103 RLSESEARKYFHQLIDGVDYCHSKGVYHRDLKPENLLLDSQG-------NLKISDFGLSA 155
Query 764 ---LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS- 819
G + ++APE L + D W G L + G P
Sbjct 156 LPEQGVTILKTTCGTPNYVAPEVLSHKGYN-GAVADIWSCGVILYVLMA-GYLPFDEMDL 213
Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
P+ + + P +L ++ L P R + I +D L+ + ++
Sbjct 214 PTLYSKIDKAEFSCPSYFALGAKSLINRILDPNPETRITIAEIRKDEWFLKDYTPVQLID 273
Query 880 VNPDSPASDPTVFHKRYLKKI 900
+ F +
Sbjct 274 YEHVNLDDVYAAFDDPEEQTY 294
>sp|Q10SC8|CIPK9_ORYSJ CBL-interacting protein kinase 9 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK9 PE=2 SV=1
Length=456
Score = 227 bits (578), Expect = 1e-63, Method: Composition-based stats.
Identities = 62/270 (23%), Positives = 118/270 (44%), Gaps = 27/270 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959
+GEG F KV + + TG+ +A+K L + +H+ K+EI ++ + H ++
Sbjct 32 TIGEGSFAKVKV----ARDTRTGDTLAIKVLDRNHVLRHKMVEQIKREISTMKLIKHPNV 87
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
++ + + + +V+EYV G L D + +G + + Q+ + Y H++
Sbjct 88 VQLHEVMASKSK--IYMVLEYVDGGELFDKIVNSGRLGEDEARRYFHQLINAVDYCHSRG 145
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N+LLD+ +K+ DFGL+ P+ E + +P + APE L + +
Sbjct 146 VYHRDLKPENLLLDSHGALKVSDFGLSAFAPQTKEDGLLHTACGTPN-YVAPEVLADKGY 204
Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
A+DVWS G+ L+ L+ P ++ L +L+ + ++ P
Sbjct 205 DGMAADVWSCGIILFVLMAGYLPFDDP---------------NLMTLYKLICKA-KVSCP 248
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+K + R T ++
Sbjct 249 HWFSSGAKKFIKRILDPNPCTRITIAQILE 278
Score = 175 bits (444), Expect = 7e-46, Method: Composition-based stats.
Identities = 59/305 (19%), Positives = 97/305 (32%), Gaps = 46/305 (15%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
RV + E+ +G+G+ V RD +
Sbjct 21 TTRVGRYEL--GKTIGEGSFAKV------------------------KVARDTRTGDTLA 54
Query 641 LKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+KVLD +H H + S M + H ++ +H V + MV EYV+ G L
Sbjct 55 IKVLDRNHVLRHKMVEQIKREISTMKLIKHPNVVQLHEVMASKSKIYMVLEYVDGGELFD 114
Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ G + QL +A+ Y ++ + H ++ N+LL G +K+
Sbjct 115 KI-VNSGRLGEDEARRYFHQLINAVDYCHSRGVYHRDLKPENLLLDSHGA-------LKV 166
Query 758 SDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
SD G+ A + ++APE L A D W G L + G
Sbjct 167 SDFGLSAFAPQTKEDGLLHTACGTPNYVAPEVLADKGYD-GMAADVWSCGIIL-FVLMAG 224
Query 812 EAPLQSRSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P + + P + L P R + IL D +
Sbjct 225 YLPFDDPNLMTLYKLICKAKVSCPHWFSSGAKKFIKRILDPNPCTRITIAQILEDDWFKK 284
Query 871 PHNLA 875
+
Sbjct 285 DYKPP 289
>sp|Q6ZLP5|CIPKN_ORYSJ CBL-interacting protein kinase 23 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK23 PE=2 SV=1
Length=450
Score = 226 bits (577), Expect = 1e-63, Method: Composition-based stats.
Identities = 67/270 (25%), Positives = 113/270 (42%), Gaps = 27/270 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959
LGEG F KV N +GE VA+K L D +H+ + K+EI ++ + H ++
Sbjct 18 TLGEGTFAKVKF----ARNADSGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNV 73
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I+ + + + +VME V G L D + R + + QQ+ + Y H++
Sbjct 74 IRMHEVMASKTK--IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 131
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N+LLD +K+ DFGL+ + E + +P + APE + +
Sbjct 132 VYHRDLKPENLLLDASGTLKVSDFGLSALSQQVREDGLLHTTCGTPN-YVAPEVINNKGY 190
Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+D+WS GV L+ L+ + ++ L + + + + P
Sbjct 191 DGAKADLWSCGVILFVLMAGYLPFED---------------SNLMSLYKKIFKAD-FSCP 234
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L+K + S R T LI
Sbjct 235 SWFSTSAKKLIKKILDPNPSTRITIAELIN 264
Score = 176 bits (446), Expect = 4e-46, Method: Composition-based stats.
Identities = 58/304 (19%), Positives = 98/304 (32%), Gaps = 44/304 (14%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
RV + E+ LG+GT V R G V +K
Sbjct 9 RVGRYEL--GRTLGEGTFAKVKFARNADSGEN------------------------VAIK 42
Query 643 VLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+LD H + S M + H ++ +H V + +V E V G L +
Sbjct 43 ILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRMHEVMASKTKIYIVMELVTGGELFDKI 102
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
RG + QQL +A+ Y ++ + H ++ N+LL S +K+SD
Sbjct 103 -ASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLD-------ASGTLKVSD 154
Query 760 PGV-GLGALSRE-----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ L RE ++APE + D W G L +
Sbjct 155 FGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD-GAKADLWSCGVILFVLMAGYLP 213
Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
S S + ++ P L + L P+ R + ++ + + +
Sbjct 214 FEDSNLMSLYKKIFKADFSCPSWFSTSAKKLIKKILDPNPSTRITIAELINNEWFKKGYQ 273
Query 874 LADV 877
Sbjct 274 PPRF 277
>sp|Q9LJF3|BRL3_ARATH Receptor-like protein kinase BRI1-like 3
OS=Arabidopsis thaliana OX=3702 GN=BRL3 PE=1 SV=1
Length=1164
Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats.
Identities = 71/283 (25%), Positives = 119/283 (42%), Gaps = 20/283 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V G +VA+K L G R + E++ + + H +++
Sbjct 864 IGSGGFGDVYKA-----KLADGSVVAIKKLIQVTGQGDRE-FMAEMETIGKIKHRNLVPL 917
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYLHA 1016
G C+ E+ LV EY+ GSL L + + + A G+A+LH
Sbjct 918 LGYCKIGEER--LLVYEYMKYGSLETVLHEKTKKGGIFLDWSARKKIAIGAARGLAFLHH 975
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
H IHRD+ + NVLLD D + ++ DFG+A+ V + V +P + PE
Sbjct 976 SCIPHIIHRDMKSSNVLLDQDFVARVSDFGMARLVSALDTHLSVSTLAGTP-GYVPPEYY 1034
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLRLTELLERGE 1132
+ ++ DV+S+GV L ELL+ + L+G A+ R E+L+
Sbjct 1035 QSFRCTAKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAKQLYREKRGAEILDPEL 1094
Query 1133 RLPRP-DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ D + C + RPT ++ + K + +
Sbjct 1095 VTDKSGDVELLHYLKIASQCLDDRPFKRPTMIQVMTMFKELVQ 1137
Score = 212 bits (539), Expect = 1e-54, Method: Composition-based stats.
Identities = 63/330 (19%), Positives = 119/330 (36%), Gaps = 69/330 (21%)
Query 576 LSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L +L+F + + S +G G +VY+ +L
Sbjct 843 LRKLTFAHLLEATNGFSADSMIGSGGFGDVYKAKLADGS--------------------- 881
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
V +K L F + ++ H +L + G C G E ++V EY+++G
Sbjct 882 ----VVAIKKLIQVTGQGDREFMAEMETIGKIKHRNLVPLLGYCKIGEERLLVYEYMKYG 937
Query 694 PLDVWLRRERGH----VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLG 746
L+ L + + + + +A A L++L + +++H ++ N+LL +
Sbjct 938 SLETVLHEKTKKGGIFLDWSARKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDQDF 997
Query 747 LAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800
+A ++SD G+ LS ++ PE + + D + +
Sbjct 998 VA-------RVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQ--SFRCTAKGDVYSY 1048
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFY------QRQHRLPEPSCPQLAT----------- 843
G LLE+ G+ P+ E + R+ R E P+L T
Sbjct 1049 GVILLELLS-GKKPIDPEEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELLHY 1107
Query 844 --LTSQCLTYEPTQRPSFRTILRDLTRLQP 871
+ SQCL P +RP+ ++ L
Sbjct 1108 LKIASQCLDDRPFKRPTMIQVMTMFKELVQ 1137
>sp|Q8L899|BRI1_SOLPE Systemin receptor SR160 OS=Solanum peruvianum
OX=4082 PE=1 SV=1
Length=1207
Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats.
Identities = 74/292 (25%), Positives = 122/292 (42%), Gaps = 30/292 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+G G FG V G +VA+K L G R + E++ + + H
Sbjct 888 FHNDSLVGSGGFGDVYKAQLK-----DGSVVAIKKLIHVSGQGDRE-FTAEMETIGKIKH 941
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGM 1011
+++ G C+ E+ LV EY+ GSL D L + A G+
Sbjct 942 RNLVPLLGYCKVGEER--LLVYEYMKYGSLEDVLHDRKKTGIKLNWPARRKIAIGAARGL 999
Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
A+LH H IHRD+ + NVLLD + ++ DFG+A+ + + V +P +
Sbjct 1000 AFLHHNCIPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTP-GYV 1058
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI----AQGQMTVLRL 1124
PE + ++ DV+S+GV L ELLT + S L+G A+G++T +
Sbjct 1059 PPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFGDNNLVGWVKLHAKGKITDVFD 1118
Query 1125 TELLERGERLPRPDKCPCEVYH---LMKNCWETEASFRPTFENLIPILKTVH 1173
ELL+ + E+ + C + RPT ++ + K +
Sbjct 1119 RELLKEDASIEI------ELLQHLKVACACLDDRHWKRPTMIQVMAMFKEIQ 1164
Score = 206 bits (523), Expect = 1e-52, Method: Composition-based stats.
Identities = 49/253 (19%), Positives = 93/253 (37%), Gaps = 49/253 (19%)
Query 576 LSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L +L+F + S +G G +VY+ +L+
Sbjct 873 LRKLTFADLLEATNGFHNDSLVGSGGFGDVYKAQLKDGS--------------------- 911
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
V +K L F + ++ H +L + G C G E ++V EY+++G
Sbjct 912 ----VVAIKKLIHVSGQGDREFTAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKYG 967
Query 694 PLDVWLRRERG---HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGL 747
L+ L + + + +A A L++L + +++H ++ N+LL
Sbjct 968 SLEDVLHDRKKTGIKLNWPARRKIAIGAARGLAFLHHNCIPHIIHRDMKSSNVLLDE--- 1024
Query 748 AEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
+ ++SD G+ LS ++ PE + ST D + +G
Sbjct 1025 ----NLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQ--SFRCSTKGDVYSYG 1078
Query 802 ATLLEICFDGEAP 814
LLE+ G+ P
Sbjct 1079 VVLLELL-TGKQP 1090
>sp|Q8GUQ5|BRI1_SOLLC Brassinosteroid LRR receptor kinase OS=Solanum
lycopersicum OX=4081 GN=CURL3 PE=1 SV=1
Length=1207
Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats.
Identities = 74/292 (25%), Positives = 122/292 (42%), Gaps = 30/292 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+G G FG V G +VA+K L G R + E++ + + H
Sbjct 888 FHNDSLVGSGGFGDVYKAQLK-----DGSVVAIKKLIHVSGQGDRE-FTAEMETIGKIKH 941
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGM 1011
+++ G C+ E+ LV EY+ GSL D L + A G+
Sbjct 942 RNLVPLLGYCKVGEER--LLVYEYMKYGSLEDVLHDRKKIGIKLNWPARRKIAIGAARGL 999
Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
A+LH H IHRD+ + NVLLD + ++ DFG+A+ + + V +P +
Sbjct 1000 AFLHHNCIPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTP-GYV 1058
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI----AQGQMTVLRL 1124
PE + ++ DV+S+GV L ELLT + S L+G A+G++T +
Sbjct 1059 PPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFGDNNLVGWVKLHAKGKITDVFD 1118
Query 1125 TELLERGERLPRPDKCPCEVYH---LMKNCWETEASFRPTFENLIPILKTVH 1173
ELL+ + E+ + C + RPT ++ + K +
Sbjct 1119 RELLKEDASIEI------ELLQHLKVACACLDDRHWKRPTMIQVMAMFKEIQ 1164
Score = 206 bits (523), Expect = 1e-52, Method: Composition-based stats.
Identities = 49/253 (19%), Positives = 93/253 (37%), Gaps = 49/253 (19%)
Query 576 LSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L +L+F + S +G G +VY+ +L+
Sbjct 873 LRKLTFADLLEATNGFHNDSLVGSGGFGDVYKAQLKDGS--------------------- 911
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
V +K L F + ++ H +L + G C G E ++V EY+++G
Sbjct 912 ----VVAIKKLIHVSGQGDREFTAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKYG 967
Query 694 PLDVWLRRERG---HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGL 747
L+ L + + + +A A L++L + +++H ++ N+LL
Sbjct 968 SLEDVLHDRKKIGIKLNWPARRKIAIGAARGLAFLHHNCIPHIIHRDMKSSNVLLDE--- 1024
Query 748 AEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
+ ++SD G+ LS ++ PE + ST D + +G
Sbjct 1025 ----NLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQ--SFRCSTKGDVYSYG 1078
Query 802 ATLLEICFDGEAP 814
LLE+ G+ P
Sbjct 1079 VVLLELL-TGKQP 1090
>sp|Q9ZPS9|BRL2_ARATH Serine/threonine-protein kinase BRI1-like
2 OS=Arabidopsis thaliana OX=3702 GN=BRL2 PE=1 SV=1
Length=1143
Score = 239 bits (611), Expect = 1e-63, Method: Composition-based stats.
Identities = 65/296 (22%), Positives = 119/296 (40%), Gaps = 34/296 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG+V G VA+K L Q + E++ L + H +++
Sbjct 844 IGHGGFGEVFKATLK-----DGSSVAIKKL-IRLSCQGDREFMAEMETLGKIKHRNLVPL 897
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEGMAYLH 1015
G C+ E+ LV E++ GSL + L R +G + A+ +G+ +LH
Sbjct 898 LGYCKIGEER--LLVYEFMQYGSLEEVLHGPRTGEKRRILGWEERKKIAKGAAKGLCFLH 955
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
H IHRD+ + NVLLD D ++ DFG+A+ + + V +P + PE
Sbjct 956 HNCIPHIIHRDMKSSNVLLDQDMEARVSDFGMARLISALDTHLSVSTLAGTP-GYVPPEY 1014
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ ++ DV+S GV + E+L+ + L+G ++ + + E+++
Sbjct 1015 YQSFRCTAKGDVYSIGVVMLEILSGKRPTDKEEFGDTNLVGWSKMKAREGKHMEVIDEDL 1074
Query 1133 RLPRPDKCPCE---------------VYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ E + C + S RP ++ L+ +
Sbjct 1075 LKEGSSESLNEKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNMLQVVASLRELR 1130
Score = 199 bits (507), Expect = 8e-51, Method: Composition-based stats.
Identities = 47/274 (17%), Positives = 94/274 (34%), Gaps = 51/274 (19%)
Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L +L F ++ + S +G G V++ L+ S
Sbjct 822 QLRKLKFSQLIEATNGFSAASMIGHGGFGEVFKATLKDGSS------------------- 862
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
V +K L F + ++ H +L + G C G E ++V E++++
Sbjct 863 ------VAIKKLIRLSCQGDREFMAEMETLGKIKHRNLVPLLGYCKIGEERLLVYEFMQY 916
Query 693 GPLDVWLRRERGH-----VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744
G L+ L R + + +A+ A L +L + +++H ++ N+LL +
Sbjct 917 GSLEEVLHGPRTGEKRRILGWEERKKIAKGAAKGLCFLHHNCIPHIIHRDMKSSNVLLDQ 976
Query 745 LGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKW 798
++SD G+ LS ++ PE + + D +
Sbjct 977 -------DMEARVSDFGMARLISALDTHLSVSTLAGTPGYVPPEYYQ--SFRCTAKGDVY 1027
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832
G +LEI G+ P + + +
Sbjct 1028 SIGVVMLEILS-GKRPTDKEEFGDTNLVGWSKMK 1060
>sp|Q94CG0|CIPKL_ARATH CBL-interacting serine/threonine-protein
kinase 21 OS=Arabidopsis thaliana OX=3702 GN=CIPK21 PE=1 SV=1
Length=416
Score = 225 bits (574), Expect = 2e-63, Method: Composition-based stats.
Identities = 76/268 (28%), Positives = 112/268 (42%), Gaps = 29/268 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHI 959
+GEG+F KV L YD TN G VAVK + Q S K+EI ++ L H +I
Sbjct 17 TIGEGNFAKVKLG-YDTTN---GTYVAVKIIDKALVIQKGLESQVKREIRTMKLLNHPNI 72
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
++ + + +VMEYV G L D L R + + QQ+ + + Y H +
Sbjct 73 VQIHEVI--GTKTKICIVMEYVSGGQLSDRLGRQKMKESDARKLFQQLIDAVDYCHNRGV 130
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
HRDL +N+LLD+ +K+ DFGL+ G + + APE + +
Sbjct 131 YHRDLKPQNLLLDSKGNLKVSDFGLSAVPKSGD----MLSTACGSPCYIAPELIMNKGYS 186
Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
A DVWS GV L+ELL T+ L + + R + P
Sbjct 187 GAAVDVWSCGVILFELLAGYPPFDD---------------HTLPVLYKKILRAD-YTFPP 230
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLI 1166
E L+ N + R T +I
Sbjct 231 GFTGEQKRLIFNILDPNPLSRITLAEII 258
Score = 174 bits (440), Expect = 1e-45, Method: Composition-based stats.
Identities = 56/311 (18%), Positives = 103/311 (33%), Gaps = 44/311 (14%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
+ ++ + EI +G+G V G D
Sbjct 1 MGLFGTKKIGKYEI--GRTIGEGNFAKVKLGY------------------------DTTN 34
Query 636 ELRVVLKVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
V +K++D + + M ++H ++ +H V + +V EYV
Sbjct 35 GTYVAVKIIDKALVIQKGLESQVKREIRTMKLLNHPNIVQIHEVIGTKTKICIVMEYVSG 94
Query 693 GPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752
G L L R++ + + + QQL A+ Y N+ + H ++ +N+LL G
Sbjct 95 GQLSDRLGRQK--MKESDARKLFQQLIDAVDYCHNRGVYHRDLKPQNLLLDSKG------ 146
Query 753 PFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
+K+SD G+ ++APE + S A+D W G L E+
Sbjct 147 -NLKVSDFGLSAVPKSGDMLSTACGSPCYIAPELIMNKGYS-GAAVDVWSCGVILFELLA 204
Query 810 DGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
G P + P + + + P + L L P R + I+ +
Sbjct 205 -GYPPFDDHTLPVLYKKILRADYTFPPGFTGEQKRLIFNILDPNPLSRITLAEIIIKDSW 263
Query 869 LQPHNLADVLT 879
+
Sbjct 264 FKIGYTPVYHQ 274
>sp|O22187|Y2232_ARATH Probable receptor-like protein kinase At2g23200
OS=Arabidopsis thaliana OX=3702 GN=At2g23200 PE=3 SV=1
Length=834
Score = 236 bits (602), Expect = 2e-63, Method: Composition-based stats.
Identities = 70/280 (25%), Positives = 119/280 (43%), Gaps = 18/280 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FG V G A+K K G Q ++ EI +L + H H++
Sbjct 494 IGKGGFGYVYKAIL-----PDGTKAAIKRGKTGSG-QGILEFQTEIQVLSRIRHRHLVSL 547
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQH- 1018
G CE+ E + LV E++ G+L+++L S+ Q L G+ YLH+
Sbjct 548 TGYCEENSE--MILVYEFMEKGTLKEHLYGSNLPSLTWKQRLEICIGAARGLDYLHSSGS 605
Query 1019 ---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
IHRD+ + N+LLD + K+ DFGL+K + + + + PE L+
Sbjct 606 EGAIIHRDVKSTNILLDEHNIAKVADFGLSKI--HNQDESNISINIKGTFGYLDPEYLQT 663
Query 1076 YKFYYASDVWSFGVTLYE-LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+K SDV++FGV L E L P + + L + + E+L+
Sbjct 664 HKLTEKSDVYAFGVVLLEVLFARPAIDPYLPHEEVNLSEWVMFCKSKGTIDEILDPSLIG 723
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ + + C + RP+ ++I L+ V +
Sbjct 724 QIETNSLKKFMEIAEKCLKEYGDERPSMRDVIWDLEYVLQ 763
Score = 225 bits (573), Expect = 7e-60, Method: Composition-based stats.
Identities = 71/359 (20%), Positives = 121/359 (34%), Gaps = 64/359 (18%)
Query 554 QPGETSNLIIMRGARASPRTLNLS---QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRV 610
+ G + N I + + R L+L + + +G+G VY+ L
Sbjct 450 RGGSSDNRPISQYHNSPLRNLHLGLTIPFTDILSATNNFDEQLLIGKGGFGYVYKAILPD 509
Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670
+ +K L F ++S++ H HL
Sbjct 510 G-------------------------TKAAIKRGKTGSGQGILEFQTEIQVLSRIRHRHL 544
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKN 729
+ G C E I+V E++E G L L + ++ + A L YL +
Sbjct 545 VSLTGYCEENSEMILVYEFMEKGTLKEHLYGSNLPSLTWKQRLEICIGAARGLDYLHSSG 604
Query 730 ----LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLA 780
++H +V NILL +A K++D G+ E + +L
Sbjct 605 SEGAIIHRDVKSTNILLDEHNIA-------KVADFGLSKIHNQDESNISINIKGTFGYLD 657
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICF-----DGEAPLQSRSPSEKEHFYQRQHRLPE 835
PE L + L+ D + FG LLE+ F D P + + SE F + + + E
Sbjct 658 PEYLQT--HKLTEKSDVYAFGVVLLEVLFARPAIDPYLPHEEVNLSEWVMFCKSKGTIDE 715
Query 836 PSCPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
P L + +CL +RPS R ++ DL + +
Sbjct 716 ILDPSLIGQIETNSLKKFMEIAEKCLKEYGDERPSMRDVIWDLEYVLQLQMMTNRREAH 774
>sp|O49545|BAME1_ARATH Leucine-rich repeat receptor-like serine/threonine-protein
kinase BAM1 OS=Arabidopsis thaliana OX=3702
GN=BAM1 PE=1 SV=1
Length=1003
Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats.
Identities = 81/312 (26%), Positives = 128/312 (41%), Gaps = 17/312 (5%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
L+ + + + LK+ +G+G G V G++VA
Sbjct 666 LKKASESRAWRLTAFQRLDFTCDDVLDSLKEDNIIGKGGAGIVYKGV-----MPNGDLVA 720
Query 929 VKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
VK L A G H G+ EI L + H HI++ G C + LV EY+P GSL
Sbjct 721 VKRLAAMSRGSSHDHGFNAEIQTLGRIRHRHIVRLLGFCSNHETN--LLVYEYMPNGSLG 778
Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGD 1041
+ L + A + +G+ YLH +HRD+ + N+LLD++ + D
Sbjct 779 EVLHGKKGGHLHWDTRYKIALEAAKGLCYLHHDCSPLIVHRDVKSNNILLDSNFEAHVAD 838
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLAK + + + S + APE K SDV+SFGV L EL+T
Sbjct 839 FGLAKFLQDSGTSECMSAIAGS-YGYIAPEYAYTLKVDEKSDVYSFGVVLLELVTGRKPV 897
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERL-PRPDKCPCEVYHLMKNCWETEASFRP 1160
++++ + + + L RL P V+++ C E +A RP
Sbjct 898 GE-FGDGVDIVQWVRKMTDSNKDSVLKVLDPRLSSIPIHEVTHVFYVAMLCVEEQAVERP 956
Query 1161 TFENLIPILKTV 1172
T ++ IL +
Sbjct 957 TMREVVQILTEI 968
Score = 197 bits (500), Expect = 4e-50, Method: Composition-based stats.
Identities = 57/323 (18%), Positives = 108/323 (33%), Gaps = 64/323 (20%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ + + +G+G VY+G + V +K L
Sbjct 692 DSLKEDNIIGKGGAGIVYKGVMPNGD-------------------------LVAVKRLAA 726
Query 647 SHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER- 703
+ F + ++ H H+ + G C N++V EY+ +G L L ++
Sbjct 727 MSRGSSHDHGFNAEIQTLGRIRHRHIVRLLGFCSNHETNLLVYEYMPNGSLGEVLHGKKG 786
Query 704 GHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
GH+ + +A + A L YL + +VH +V NILL ++ ++D
Sbjct 787 GHLHWDTRYKIALEAAKGLCYLHHDCSPLIVHRDVKSNNILLD-------SNFEAHVADF 839
Query 761 GVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ ++APE + D + FG LLE+ G P
Sbjct 840 GLAKFLQDSGTSECMSAIAGSYGYIAPEYA--YTLKVDEKSDVYSFGVVLLELV-TGRKP 896
Query 815 -----------------LQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857
S S + R +P + + C+ + +RP
Sbjct 897 VGEFGDGVDIVQWVRKMTDSNKDSVLKVLDPRLSSIPIHEVTHVFYVAMLCVEEQAVERP 956
Query 858 SFRTILRDLTRLQPHNLADVLTV 880
+ R +++ LT + + +
Sbjct 957 TMREVVQILTEIPKLPPSKDQPM 979
>sp|P51957|NEK4_HUMAN Serine/threonine-protein kinase Nek4 OS=Homo
sapiens OX=9606 GN=NEK4 PE=1 SV=2
Length=841
Score = 236 bits (602), Expect = 2e-63, Method: Composition-based stats.
Identities = 64/274 (23%), Positives = 116/274 (42%), Gaps = 27/274 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLY 955
+R +G+G +G+V+L + G+ +K L + + R +QE +L L
Sbjct 6 YCYLRVVGKGSYGEVTLV----KHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLK 61
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMA 1012
H +I+ YK E G+ L +VM + G L L + Q++ + QI +
Sbjct 62 HPNIVTYKESWE-GGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ 120
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
YLH +H +HRDL +NV L ++K+GD G+A+ + + + ++ +PE
Sbjct 121 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVL---ENHCDMASTLIGTPYYMSPEL 177
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ Y SDVW+ G +YE+ T + + L + G+
Sbjct 178 FSNKPYNYKSDVWALGCCVYEMATLKHAF---------------NAKDMNSLVYRIIEGK 222
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
P P E+ L++ RP+ +++
Sbjct 223 LPPMPRDYSPELAELIRTMLSKRPEERPSVRSIL 256
Score = 176 bits (445), Expect = 8e-44, Method: Composition-based stats.
Identities = 60/284 (21%), Positives = 105/284 (37%), Gaps = 38/284 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
L +G+G+ V LV R G++ + L +
Sbjct 8 YLRVVGKGSYGEV----------------------TLVKHRRDGKQYVIKKLNLRNASSR 45
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHV-PM 708
A + A L+SQ+ H ++ G +V + E G L L+ ++G + P
Sbjct 46 ERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPE 105
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ Q+A AL YL K+++H ++ +N+ L R + IK+ D G+ +
Sbjct 106 NQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNI-------IKVGDLGIARVLEN 158
Query 769 R----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ +++PE + D W G + E+ A S
Sbjct 159 HCDMASTLIGTPYYMSPELFSNKPYNY--KSDVWALGCCVYEMATLKHAFNAKDMNSLVY 216
Query 825 HFYQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ + +P P+LA L L+ P +RPS R+ILR
Sbjct 217 RIIEGKLPPMPRDYSPELAELIRTMLSKRPEERPSVRSILRQPY 260
>sp|Q6UD73|LYK3_MEDTR LysM domain receptor-like kinase 3 OS=Medicago
truncatula OX=3880 GN=LYK3 PE=1 SV=1
Length=620
Score = 231 bits (590), Expect = 2e-63, Method: Composition-based stats.
Identities = 69/296 (23%), Positives = 119/296 (40%), Gaps = 28/296 (9%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G+G FG V GE A+K + S + E+ +L ++H ++
Sbjct 325 DNKIGQGGFGAVYYAELR------GEKTAIKKMDVQAS----SEFLCELKVLTHVHHLNL 374
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHA 1016
++ G C E SL LV E++ G+L YL + + + A G+ Y+H
Sbjct 375 VRLIGYCV---EGSLFLVYEHIDNGNLGQYLHGIGTEPLPWSSRVQIALDSARGLEYIHE 431
Query 1017 QHY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRD+ + N+L+D + K+ DFGL K + G+ R + PE
Sbjct 432 HTVPVYIHRDVKSANILIDKNLRGKVADFGLTKLIEVGNSTLHTR--LVGTFGYMPPEYA 489
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR-------LTE 1126
+ DV++FGV LYEL+T ++ E G+ Q L L +
Sbjct 490 QYGDVSPKIDVYAFGVVLYELITAKNAVLKTGESVAESKGLVQLFEEALHRMDPLEGLRK 549
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182
L++ + P ++ L + C RP+ +++ L T+ +
Sbjct 550 LVDPRLKENYPIDSVLKMAQLGRACTRDNPLLRPSMRSIVVALMTLSSPTEDCDDD 605
Score = 189 bits (479), Expect = 4e-49, Method: Composition-based stats.
Identities = 65/333 (20%), Positives = 116/333 (35%), Gaps = 71/333 (21%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ + +GQG VY LR E + +K +
Sbjct 318 ATNNFSLDNKIGQGGFGAVYYAELRGEKT--------------------------AIKKM 351
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ER 703
D + F +++ V H +L + G CV G +V E++++G L +L
Sbjct 352 D---VQASSEFLCELKVLTHVHHLNLVRLIGYCVEGS-LFLVYEHIDNGNLGQYLHGIGT 407
Query 704 GHVPMAWKMVVAQQLASALSYLENKNL---VHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+P + ++ +A A L Y+ + +H +V NIL+ + + K++D
Sbjct 408 EPLPWSSRVQIALDSARGLEYIHEHTVPVYIHRDVKSANILIDK-------NLRGKVADF 460
Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP- 814
G+ + V ++ PE G +S +D + FG L E+ A
Sbjct 461 GLTKLIEVGNSTLHTRLVGTFGYMPPEYAQYG--DVSPKIDVYAFGVVLYELITAKNAVL 518
Query 815 LQSRSPSE----KEHFYQRQHRL------------------PEPSCPQLATLTSQCLTYE 852
S +E + F + HR+ P S ++A L C
Sbjct 519 KTGESVAESKGLVQLFEEALHRMDPLEGLRKLVDPRLKENYPIDSVLKMAQLGRACTRDN 578
Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885
P RPS R+I+ L L + ++
Sbjct 579 PLLRPSMRSIVVALMTLSSPTEDCDDDSSYENQ 611
>sp|P48963|CDK2_MESAU Cyclin-dependent kinase 2 OS=Mesocricetus
auratus OX=10036 GN=CDK2 PE=2 SV=1
Length=298
Score = 221 bits (563), Expect = 2e-63, Method: Composition-based stats.
Identities = 68/289 (24%), Positives = 121/289 (42%), Gaps = 30/289 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+
Sbjct 1 MENFQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICE 1009
L H +I+K E L LV E + L+ ++ I L + + Q+ +
Sbjct 57 ELNHPNIVKLLDVI--HTENKLYLVFELLHQ-DLKKFMDASAVTGIPLPLIKSYLFQLLQ 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
G+A+ H+ +HRDL +N+L++ + +K+ DFGLA+A R +++ A
Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVP---VRTYTHEVVTLWYRA 170
Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL- 1127
PE L K+Y A D+WS G E++T ++ +L I + T +
Sbjct 171 PEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPG-DSEIDQLFRIFRTLGTPDEVVWPG 229
Query 1128 --LERGERLPRPDKCPCEV-----------YHLMKNCWETEASFRPTFE 1163
+ P + L+ + + R + +
Sbjct 230 VTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAK 278
Score = 169 bits (427), Expect = 3e-45, Method: Composition-based stats.
Identities = 47/266 (18%), Positives = 94/266 (35%), Gaps = 40/266 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
+ ++ +G+GT VY+ + ++ G V LK
Sbjct 1 MENFQKVEKIGEGTYGVVYKAKNKLTGE------------------------VVALKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
LD + SL+ +++H ++ + V + +V E + H L ++
Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFELL-HQDLKKFMDASA 95
Query 704 -GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+P+ QL L++ + ++H ++ +N+L+ G IKL+D G+
Sbjct 96 VTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEG-------SIKLADFGL 148
Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + + APE L G STA+D W G E+
Sbjct 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKY-YSTAVDIWSLGCIFAEMVTRRALFPGDS 207
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ E P + ++
Sbjct 208 EIDQLFRIFRTLGTPDEVVWPGVTSM 233
>sp|Q9SHI2|Y1723_ARATH Leucine-rich repeat receptor-like serine/threonine-protein
kinase At1g17230 OS=Arabidopsis thaliana
OX=3702 GN=At1g17230 PE=1 SV=2
Length=1101
Score = 239 bits (610), Expect = 2e-63, Method: Composition-based stats.
Identities = 83/344 (24%), Positives = 126/344 (37%), Gaps = 28/344 (8%)
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899
L T C T + L ++ D V R +
Sbjct 747 FLITFLGLCWTIK-----RREPAFVALEDQTKPDVMDSYYFPKKGFTYQGLVDATRNFSE 801
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEH 958
LG G G V GE++AVK L + G + ++ EI L + H +
Sbjct 802 DVVLGRGACGTVYKAEMSG-----GEVIAVKKLNSRGEGASSDNSFRAEISTLGKIRHRN 856
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYL 1014
I+K G C Q L+ EY+ GSL + L R + A EG+ YL
Sbjct 857 IVKLYGFCYHQNSN--LLLYEYMSKGSLGEQLQRGEKNCLLDWNARYRIALGAAEGLCYL 914
Query 1015 HA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
H +HRD+ + N+LLD +GDFGLAK + Y + + APE
Sbjct 915 HHDCRPQIVHRDIKSNNILLDERFQAHVGDFGLAKLID--LSYSKSMSAVAGSYGYIAPE 972
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
K D++SFGV L EL+T Q P + +L+ + + + + +
Sbjct 973 YAYTMKVTEKCDIYSFGVVLLELITGKPPVQ-PLEQGGDLVNWVRRSIRNM-IPTIEMFD 1030
Query 1132 ERLPRPDKCPCE----VYHLMKNCWETEASFRPTFENLIPILKT 1171
RL DK V + C + RPT ++ ++
Sbjct 1031 ARLDTNDKRTVHEMSLVLKIALFCTSNSPASRPTMREVVAMITE 1074
Score = 189 bits (481), Expect = 1e-47, Method: Composition-based stats.
Identities = 49/272 (18%), Positives = 92/272 (34%), Gaps = 49/272 (18%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ ++ LG+G VY+ + + +K L
Sbjct 795 ATRNFSEDVVLGRGACGTVYKAEMSGGE-------------------------VIAVKKL 829
Query 645 DPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+ + F S + ++ H ++ ++G C N+++ EY+ G L L+R
Sbjct 830 NSRGEGASSDNSFRAEISTLGKIRHRNIVKLYGFCYHQNSNLLLYEYMSKGSLGEQLQRG 889
Query 703 RGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ + W + +A A L YL + +VH ++ NILL A +
Sbjct 890 EKNCLLDWNARYRIALGAAEGLCYLHHDCRPQIVHRDIKSNNILLDERFQAH-------V 942
Query 758 SDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
D G+ + S ++APE ++ D + FG LLE+ G+
Sbjct 943 GDFGLAKLIDLSYSKSMSAVAGSYGYIAPEYA--YTMKVTEKCDIYSFGVVLLELI-TGK 999
Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATL 844
P+Q + R P +
Sbjct 1000 PPVQPL--EQGGDLVNWVRRSIRNMIPTIEMF 1029
>sp|A4K2W5|STK4_AOTNA Serine/threonine-protein kinase 4 OS=Aotus
nancymaae OX=37293 GN=STK4 PE=3 SV=1
Length=487
Score = 228 bits (580), Expect = 2e-63, Method: Composition-based stats.
Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K
Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSHHVVK 87
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+K C R T L+
Sbjct 250 WSDNFTDFVKQCLVKSPEQRATATQLLQ 277
Score = 199 bits (507), Expect = 7e-54, Method: Composition-based stats.
Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L + S + ++ L LG+G+ +VY+ + G
Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K + + S+M Q H+ +G + + +V EY G +
Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSHHVVKYYGSYFKNTDLWIVMEYCGAGSV 110
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + Q L YL +H ++ NILL G
Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163
Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D GV R + W+APE + + D W G T +E+ +G
Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQE--IGYNCVADIWSLGITAIEMA-EG 220
Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P P R PE QCL P QR + +L+
Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPF 280
>sp|Q8QFP8|LIMK1_CHICK LIM domain kinase 1 OS=Gallus gallus OX=9031
GN=LIMK1 PE=1 SV=1
Length=662
Score = 232 bits (592), Expect = 2e-63, Method: Composition-based stats.
Identities = 73/306 (24%), Positives = 130/306 (42%), Gaps = 33/306 (11%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
+F L LG+G FG+ T+ TGE++ +K L + + + +E+
Sbjct 338 HRIFRPSDLIHGEVLGKGCFGQ----AIKVTHRETGEVMVMKEL-IRFDEETQRTFLKEV 392
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQ 1006
++R L H +++K+ G EK L + EY+ G+LR + +Q + FA+
Sbjct 393 KVMRCLEHPNVLKFIGVLYK--EKRLNFITEYIKGGTLRGLIKSMDSHYPWSQRVSFAKD 450
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-----------Y 1055
I GMAYLH+ + IHRDL + N L+ ++ V + DFGLA+ + +
Sbjct 451 IAAGMAYLHSMNIIHRDLNSHNCLVRENKSVVVADFGLARLMVDEKNQPEHLQNLKKPDR 510
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
+ R +W APE + + D++SFG+ L E++ + + +
Sbjct 511 KKRYTVVGNPYWMAPEMINGRSYDEKVDIFSFGIVLCEIIGRVSADPDYLPRTTDFGLNV 570
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
+G + P CP + + C + + RP+F L L+T+
Sbjct 571 RGFLERY-------------CPPACPPSFFPIAACCCDLDPEKRPSFSKLEQWLETLRMH 617
Query 1176 YQGQAP 1181
+ P
Sbjct 618 LDIRLP 623
Score = 203 bits (517), Expect = 1e-53, Method: Composition-based stats.
Identities = 57/308 (19%), Positives = 111/308 (36%), Gaps = 54/308 (18%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ LG+G + R G +V+K L
Sbjct 343 PSDLIHGEVLGKGCFGQAIKVTHRETGE------------------------VMVMKELI 378
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ F + +M + H ++ GV + +TEY++ G L ++ H
Sbjct 379 RFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKEKRLNFITEYIKGGTLRGLIKSMDSH 438
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
P + ++ A+ +A+ ++YL + N++H ++ N L+ + + ++D G+
Sbjct 439 YPWSQRVSFAKDIAAGMAYLHSMNIIHRDLNSHNCLVRE-------NKSVVVADFGLARL 491
Query 766 ALSRE------------------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+ + V W+APE + G S +D + FG L EI
Sbjct 492 MVDEKNQPEHLQNLKKPDRKKRYTVVGNPYWMAPEMING--RSYDEKVDIFSFGIVLCEI 549
Query 808 C--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILR 864
+ R+ + R P+CP + + C +P +RPSF + +
Sbjct 550 IGRVSADPDYLPRTTDFGLNVRGFLERYCPPACPPSFFPIAACCCDLDPEKRPSFSKLEQ 609
Query 865 DLTRLQPH 872
L L+ H
Sbjct 610 WLETLRMH 617
>sp|Q863I2|OXSR1_PIG Serine/threonine-protein kinase OSR1 OS=Sus
scrofa OX=9823 GN=OXSR1 PE=2 SV=1
Length=529
Score = 229 bits (583), Expect = 2e-63, Method: Composition-based stats.
Identities = 73/293 (25%), Positives = 122/293 (42%), Gaps = 30/293 (10%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
P +K + +G G V P E VA+K + + +EI
Sbjct 9 PWSINKDDYELQEVIGSGATAVVQAAYCTPKK----EKVAIKRINLEKCQTSMDELLKEI 64
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQ 999
+ +H +I+ Y + E L LVM+ + GS+ D + + A
Sbjct 65 QAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEAT 122
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--V 1057
+ +++ EG+ YLH IHRD+ A N+LL D V+I DFG++ + G + R V
Sbjct 123 IATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKV 182
Query 1058 REDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQS-PPTK--FLELIG 1113
R+ W APE +++ + + +D+WSFG+T EL T PP K L L
Sbjct 183 RKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQN 242
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
T ++ E+L++ + ++ C + + RPT L+
Sbjct 243 DPPSLETGVQDKEMLKKYGK---------SFRKMISLCLQKDPEKRPTAAELL 286
Score = 177 bits (449), Expect = 8e-46, Method: Composition-based stats.
Identities = 52/315 (17%), Positives = 102/315 (32%), Gaps = 61/315 (19%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+++ + +G G V ++ +V +
Sbjct 10 WSINKDDYELQEVIGSGATAVV------------------------QAAYCTPKKEKVAI 45
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K ++ ++ + MSQ H ++ + V E +V + + G + ++
Sbjct 46 KRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIK 105
Query 701 R-------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
+ G + A + +++ L YL +H +V NILL G
Sbjct 106 HIVAKGEHKSGVLDEATIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG------- 158
Query 754 FIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
++++D GV + R+ V W+APE + D W FG T
Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKADIWSFGITA 217
Query 805 LEICFDGEAPLQSRSPSEKEHFY-----------QRQHRLPEPSCPQLATLTSQCLTYEP 853
+E+ G AP P + + + + + S CL +P
Sbjct 218 IELA-TGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDP 276
Query 854 TQRPSFRTILRDLTR 868
+RP+ +LR
Sbjct 277 EKRPTAAELLRHKFF 291
>sp|Q9LHP4|RGI1_ARATH LRR receptor-like serine/threonine-protein
kinase RGI1 OS=Arabidopsis thaliana OX=3702 GN=RGI1 PE=1
SV=1
Length=1141
Score = 239 bits (611), Expect = 2e-63, Method: Composition-based stats.
Identities = 77/316 (24%), Positives = 127/316 (40%), Gaps = 23/316 (7%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--- 932
P + R L + +G+G G V + GE++AVK L
Sbjct 765 YKWQFTPFQKLNFSVDQIIRCLVEPNVIGKGCSGVVYRA-----DVDNGEVIAVKKLWPA 819
Query 933 -----KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
+ R + E+ L T+ H++I+++ GCC ++ + L +Y+P GSL
Sbjct 820 MVNGGHDEKTKNVRDSFSAEVKTLGTIRHKNIVRFLGCCWNRNTRLLM--YDYMPNGSLG 877
Query 988 DYLPRH---SIGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGD 1041
L S+ +G+AYLH +HRD+ A N+L+ D I D
Sbjct 878 SLLHERRGSSLDWDLRYRILLGAAQGLAYLHHDCLPPIVHRDIKANNILIGLDFEPYIAD 937
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLAK V EG + R + APE K SDV+S+GV + E+LT
Sbjct 938 FGLAKLVDEG-DIGRCSNTVAGSYGYIAPEYGYSMKITEKSDVYSYGVVVLEVLTGKQPI 996
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ + L+ + L + + R R +V C + RPT
Sbjct 997 DPTVPEGIHLVDWVRQNRGSLEVLDSTLRS-RTEAEADEMMQVLGTALLCVNSSPDERPT 1055
Query 1162 FENLIPILKTVHEKYQ 1177
+++ +LK + ++ +
Sbjct 1056 MKDVAAMLKEIKQERE 1071
Score = 186 bits (472), Expect = 1e-46, Method: Composition-based stats.
Identities = 73/444 (16%), Positives = 149/444 (34%), Gaps = 71/444 (16%)
Query 403 LELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSI------RDGIHGPLL 456
L +PS+ A+L+ +S++D S + L ++AP + ++ + G L
Sbjct 623 LTGKIPSKIASLNKLSILDL-------SHNMLEGDLAPLANIENLVSLNISYNSFSGYLP 675
Query 457 EPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVL 516
+ + +L P+D +S LT + + D + R RK + +
Sbjct 676 DNKLFRQLSPQDLEGNKKLCSSTQDSCFLTYRKGNGLGDDGDASRTRKLRLTLALLITLT 735
Query 517 EGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL 576
L+ G R + ++ + + LN
Sbjct 736 V------------------VLMILGAVAVIRARRNIDNERDSELGETYKWQFTPFQKLNF 777
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S R + + + +G+G VY D + G++ L P G
Sbjct 778 SVDQIIRC----LVEPNVIGKGCSGVVYRA--------DVDNGEVIAVKKLWPAMVNGGH 825
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
D ++ +F + + H ++ G C +++ +Y+ +G L
Sbjct 826 --------DEKTKNVRDSFSAEVKTLGTIRHKNIVRFLGCCWNRNTRLLMYDYMPNGSLG 877
Query 697 VWLRRERG-HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752
L RG + + + A L+YL + +VH ++ NIL+ G
Sbjct 878 SLLHERRGSSLDWDLRYRILLGAAQGLAYLHHDCLPPIVHRDIKANNILI-------GLD 930
Query 753 PFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
++D G+ + ++APE G + ++ D + +G +LE
Sbjct 931 FEPYIADFGLAKLVDEGDIGRCSNTVAGSYGYIAPEY--GYSMKITEKSDVYSYGVVVLE 988
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQ 830
+ G+ P+ P +
Sbjct 989 VL-TGKQPIDPTVPEGIHLVDWVR 1011
>sp|Q9LYX1|LRK82_ARATH L-type lectin-domain containing receptor
kinase VIII.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK82 PE=2
SV=1
Length=711
Score = 233 bits (595), Expect = 2e-63, Method: Composition-based stats.
Identities = 68/290 (23%), Positives = 118/290 (41%), Gaps = 29/290 (10%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R +G G FG V Y +GE++A+K Q + + E+ ++ TL
Sbjct 372 DCFSSSRVIGNGAFGTV----YKGILQDSGEIIAIKRCSHIS--QGNTEFLSELSLIGTL 425
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMA 1012
H ++++ +G C ++GE + L+ + +P GSL L + + +A
Sbjct 426 RHRNLLRLQGYCREKGE--ILLIYDLMPNGSLDKALYESPTTLPWPHRRKILLGVASALA 483
Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH IHRD+ N++LD + K+GDFGLA+ + + A
Sbjct 484 YLHQECENQIIHRDVKTSNIMLDANFNPKLGDFGLARQTEHDKSPDAT--AAAGTMGYLA 541
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-------PTKFLELIGIAQGQMTVL 1122
PE L + +DV+S+G + E+ T P P L+ G
Sbjct 542 PEYLLTGRATEKTDVFSYGAVVLEVCTGRRPITRPEPEPGLRPGLRSSLVDWVWGLYREG 601
Query 1123 RLTELLERGERLPRPDKCPCEVYHLM---KNCWETEASFRPTFENLIPIL 1169
+L ++ + P E+ +M C + + RPT +++ IL
Sbjct 602 KLLTAVDERL----SEFNPEEMSRVMMVGLACSQPDPVTRPTMRSVVQIL 647
Score = 216 bits (551), Expect = 8e-58, Method: Composition-based stats.
Identities = 63/323 (20%), Positives = 111/323 (34%), Gaps = 67/323 (21%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
SPR +L ++ + +G G VY+G L+ G
Sbjct 358 SPREFTYKEL---KLATDCFSSSRVIGNGAFGTVYKGILQDSGE---------------- 398
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
+ +K F SL+ + H +L + G C E +++ +
Sbjct 399 --------IIAIKRCSHIS-QGNTEFLSELSLIGTLRHRNLLRLQGYCREKGEILLIYDL 449
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLG 746
+ +G LD L +P + + +ASAL+YL ++H +V NI+L
Sbjct 450 MPNGSLDKALYESPTTLPWPHRRKILLGVASALAYLHQECENQIIHRDVKTSNIMLD--- 506
Query 747 LAEGTSPFIKLSDPGVGLGALSREE-----RVERIPWLAPECLPGGANSLSTAMDKWGFG 801
+ KL D G+ + + +LAPE L G + D + +G
Sbjct 507 ----ANFNPKLGDFGLARQTEHDKSPDATAAAGTMGYLAPEYLLTGRA--TEKTDVFSYG 560
Query 802 ATLLEICFDGEA-----PLQSRSP--------------SEKEHFYQRQHRLPEPSCPQLA 842
A +LE+C P P E + RL E + +++
Sbjct 561 AVVLEVCTGRRPITRPEPEPGLRPGLRSSLVDWVWGLYREGKLLTAVDERLSEFNPEEMS 620
Query 843 TLTS---QCLTYEPTQRPSFRTI 862
+ C +P RP+ R++
Sbjct 621 RVMMVGLACSQPDPVTRPTMRSV 643
>sp|Q5R495|OXSR1_PONAB Serine/threonine-protein kinase OSR1 OS=Pongo
abelii OX=9601 GN=OXSR1 PE=2 SV=1
Length=527
Score = 229 bits (583), Expect = 2e-63, Method: Composition-based stats.
Identities = 71/293 (24%), Positives = 122/293 (42%), Gaps = 30/293 (10%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
P ++ + +G G V P E VA+K + + +EI
Sbjct 9 PWSINRDDYELQEVIGSGATAVVQAAYCAPKK----EKVAIKRINLEKCQTSMDELLKEI 64
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQ 999
+ +H +I+ Y + E L LVM+ + GS+ D + + +
Sbjct 65 QAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEST 122
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--V 1057
+ +++ EG+ YLH IHRD+ A N+LL D V+I DFG++ + G + R V
Sbjct 123 IATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKV 182
Query 1058 REDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQS-PPTK--FLELIG 1113
R+ W APE +++ + + +D+WSFG+T EL T PP K L L
Sbjct 183 RKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQN 242
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
T ++ E+L++ + ++ C + + RPT L+
Sbjct 243 DPPSLETGVQDKEMLKKYGK---------SFRKMISLCLQKDPEKRPTAAELL 286
Score = 178 bits (451), Expect = 4e-46, Method: Composition-based stats.
Identities = 51/315 (16%), Positives = 102/315 (32%), Gaps = 61/315 (19%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+++ + +G G V ++ +V +
Sbjct 10 WSINRDDYELQEVIGSGATAVV------------------------QAAYCAPKKEKVAI 45
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K ++ ++ + MSQ H ++ + V E +V + + G + ++
Sbjct 46 KRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIK 105
Query 701 R-------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
+ G + + + +++ L YL +H +V NILL G
Sbjct 106 HIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG------- 158
Query 754 FIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
++++D GV + R+ V W+APE + D W FG T
Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKADIWSFGITA 217
Query 805 LEICFDGEAPLQSRSPSEKEHFY-----------QRQHRLPEPSCPQLATLTSQCLTYEP 853
+E+ G AP P + + + + + S CL +P
Sbjct 218 IELA-TGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDP 276
Query 854 TQRPSFRTILRDLTR 868
+RP+ +LR
Sbjct 277 EKRPTAAELLRHKFF 291
>sp|O95747|OXSR1_HUMAN Serine/threonine-protein kinase OSR1 OS=Homo
sapiens OX=9606 GN=OXSR1 PE=1 SV=1
Length=527
Score = 229 bits (583), Expect = 2e-63, Method: Composition-based stats.
Identities = 71/293 (24%), Positives = 122/293 (42%), Gaps = 30/293 (10%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
P ++ + +G G V P E VA+K + + +EI
Sbjct 9 PWSINRDDYELQEVIGSGATAVVQAAYCAPKK----EKVAIKRINLEKCQTSMDELLKEI 64
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQ 999
+ +H +I+ Y + E L LVM+ + GS+ D + + +
Sbjct 65 QAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEST 122
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--V 1057
+ +++ EG+ YLH IHRD+ A N+LL D V+I DFG++ + G + R V
Sbjct 123 IATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKV 182
Query 1058 REDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQS-PPTK--FLELIG 1113
R+ W APE +++ + + +D+WSFG+T EL T PP K L L
Sbjct 183 RKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQN 242
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
T ++ E+L++ + ++ C + + RPT L+
Sbjct 243 DPPSLETGVQDKEMLKKYGK---------SFRKMISLCLQKDPEKRPTAAELL 286
Score = 178 bits (451), Expect = 4e-46, Method: Composition-based stats.
Identities = 51/315 (16%), Positives = 102/315 (32%), Gaps = 61/315 (19%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+++ + +G G V ++ +V +
Sbjct 10 WSINRDDYELQEVIGSGATAVV------------------------QAAYCAPKKEKVAI 45
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K ++ ++ + MSQ H ++ + V E +V + + G + ++
Sbjct 46 KRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIK 105
Query 701 R-------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
+ G + + + +++ L YL +H +V NILL G
Sbjct 106 HIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG------- 158
Query 754 FIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
++++D GV + R+ V W+APE + D W FG T
Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKADIWSFGITA 217
Query 805 LEICFDGEAPLQSRSPSEKEHFY-----------QRQHRLPEPSCPQLATLTSQCLTYEP 853
+E+ G AP P + + + + + S CL +P
Sbjct 218 IELA-TGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDP 276
Query 854 TQRPSFRTILRDLTR 868
+RP+ +LR
Sbjct 277 EKRPTAAELLRHKFF 291
>sp|A7E3S4|RAF1_BOVIN RAF proto-oncogene serine/threonine-protein
kinase OS=Bos taurus OX=9913 GN=RAF1 PE=2 SV=1
Length=648
Score = 232 bits (591), Expect = 2e-63, Method: Composition-based stats.
Identities = 79/333 (24%), Positives = 136/333 (41%), Gaps = 35/333 (11%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
+ T P+ R + + + +S + +G G F
Sbjct 305 WSQPKTPAPAQRERAPGSST----QEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF 360
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
G V + VAVK LK D P+ ++ E+ +LR H +I+ + G
Sbjct 361 GTVYKGKWHG-------DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYM- 412
Query 968 DQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
+ +L +V ++ SL +L + QL+ A+Q +GM YLHA++ IHRD+
Sbjct 413 --TKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMK 470
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYAS 1082
+ N+ L VKIGDFGLA +V E + W APE ++ F + S
Sbjct 471 SNNIFLHEGLTVKIGDFGLATVKSRWSGSQQV-EQPTGSILWMAPEVIRMQDNNPFSFQS 529
Query 1083 DVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
DV+S+G+ LYEL+T + + ++G + +L + C
Sbjct 530 DVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYK------------NC 577
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
P + L+ +C + RP F ++ ++ +
Sbjct 578 PKAMKRLVADCVKKVKEERPLFPQILSSIELLQ 610
Score = 222 bits (565), Expect = 5e-60, Method: Composition-based stats.
Identities = 70/367 (19%), Positives = 126/367 (34%), Gaps = 62/367 (17%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
R + N I RG R S + ++ E+ + +G G+ VY+G+
Sbjct 316 RERAPGSSTQEKNKIRPRGQRDSSY--------YWEIEASEVMLSTRIGSGSFGTVYKGK 367
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQ 664
+ V +K+L DP+ AF +++ +
Sbjct 368 WHGD---------------------------VAVKILKVVDPTPEQFQ-AFRNEVAVLRK 399
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
H ++ G + +VT++ E L L + M + +A+Q A + Y
Sbjct 400 TRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778
L KN++H ++ NI L +K+ D G+ G+ E+ I W
Sbjct 459 LHAKNIIHRDMKSNNIFLHEGL-------TVKIGDFGLATVKSRWSGSQQVEQPTGSILW 511
Query 779 LAPECLPGGA-NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------ 831
+APE + N S D + +G L E+ GE P + ++ F +
Sbjct 512 MAPEVIRMQDNNPFSFQSDVYSYGIVLYELM-TGELPYSHINNRDQIIFMVGRGYASPDL 570
Query 832 -RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
+L + + L + C+ +RP F IL + LQ + + S
Sbjct 571 SKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAH 630
Query 891 VFHKRYL 897
Sbjct 631 TEDINAC 637
>sp|O04533|LRK52_ARATH Putative L-type lectin-domain containing
receptor kinase V.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK52
PE=3 SV=1
Length=656
Score = 232 bits (591), Expect = 2e-63, Method: Composition-based stats.
Identities = 72/277 (26%), Positives = 117/277 (42%), Gaps = 16/277 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FGKV + + +AVK + D Q + EI + L H +++
Sbjct 340 LGKGGFGKV----FKGILPLSSIPIAVKKISHD-SRQGMREFLAEIATIGRLRHPDLVRL 394
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018
G C +GE L LV +++P GSL +L P + +Q + + G+ YLH Q
Sbjct 395 LGYCRRKGE--LYLVYDFMPKGSLDKFLYNQPNQILDWSQRFNIIKDVASGLCYLHQQWV 452
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ N+LLD + K+GDFGLAK G + + + +PE +
Sbjct 453 QVIIHRDIKPANILLDENMNAKLGDFGLAKLCDHGIDSQT--SNVAGTFGYISPELSRTG 510
Query 1077 KFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
K +SDV++FGV + E+ + L + ++++
Sbjct 511 KSSTSSDVFAFGVFMLEITCGRRPIGPRGSPSEMVLTDWVLDCWDSGDILQVVDEKLGHR 570
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ V L C A+ RP+ ++I L V
Sbjct 571 YLAEQVTLVLKLGLLCSHPVAATRPSMSSVIQFLDGV 607
Score = 220 bits (561), Expect = 2e-59, Method: Composition-based stats.
Identities = 59/308 (19%), Positives = 105/308 (34%), Gaps = 59/308 (19%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ K LG+G V++G L + + + +K
Sbjct 329 IATKGFKNSEVLGKGGFGKVFKGILPL------------------------SSIPIAVKK 364
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ F + + ++ H L + G C R E +V +++ G LD +L +
Sbjct 365 ISHDSRQGMREFLAEIATIGRLRHPDLVRLLGYCRRKGELYLVYDFMPKGSLDKFLYNQP 424
Query 704 GH-VPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ + + + + +AS L YL + ++H ++ NILL + KL D
Sbjct 425 NQILDWSQRFNIIKDVASGLCYLHQQWVQVIIHRDIKPANILLDE-------NMNAKLGD 477
Query 760 PGVGL----GALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ G S+ V +++PE G + ST+ D + FG +LEI
Sbjct 478 FGLAKLCDHGIDSQTSNVAGTFGYISPELSRTGKS--STSSDVFAFGVFMLEITCGRRPI 535
Query 815 LQSRSPSEKEHFYQR-----------------QHRLPEPSCPQLATLTSQCLTYEPTQRP 857
SPSE HR + L C RP
Sbjct 536 GPRGSPSEMVLTDWVLDCWDSGDILQVVDEKLGHRYLAEQVTLVLKLGLLCSHPVAATRP 595
Query 858 SFRTILRD 865
S ++++
Sbjct 596 SMSSVIQF 603
>sp|Q5TCX8|M3K21_HUMAN Mitogen-activated protein kinase kinase
kinase 21 OS=Homo sapiens OX=9606 GN=MAP3K21 PE=1 SV=3
Length=1036
Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats.
Identities = 86/308 (28%), Positives = 129/308 (42%), Gaps = 56/308 (18%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR---SGWKQEIDILRTLYHEHI 959
+G G FG+V + G+ VAVKA + D ++E + L H +I
Sbjct 130 IGAGGFGQVYRATWQ------GQEVAVKAARQDPEQDAAAAAESVRREARLFAMLRHPNI 183
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------------IGLAQLLLFA 1004
I+ +G C Q L LV+E+ G+L L + I L+ +A
Sbjct 184 IELRGVCLQQ--PHLCLVLEFARGGALNRALAAANAAPDPRAPGPRRARRIPPHVLVNWA 241
Query 1005 QQICEGMAYLHAQ---HYIHRDLAARNVLLDN--------DRLVKIGDFGLAKAVPEGHE 1053
QI GM YLH + +HRDL + N+LL ++ +KI DFGLA+
Sbjct 242 VQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLAR-----EW 296
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
+ + W APE +K F SD+WS+GV L+ELLT P + ++ +
Sbjct 297 HRTTKMSTAGTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTG-----EVPYRGIDGLA 351
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+A G LP P CP LMK CW+ + RP+F ++ L +
Sbjct 352 VAYGVAVN---------KLTLPIPSTCPEPFAKLMKECWQQDPHIRPSFALILEQLTAIE 402
Query 1174 EKYQGQAP 1181
+ P
Sbjct 403 GAVMTEMP 410
Score = 207 bits (528), Expect = 1e-53, Method: Composition-based stats.
Identities = 82/466 (18%), Positives = 152/466 (33%), Gaps = 58/466 (12%)
Query 514 FVLEGWGRSFPSVR--ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASP 571
+ E G S+R +L L +GD+ + + +N + ASP
Sbjct 47 YDYEARGEDELSLRRGQLVEVLSQDAAVSGDEGWWAGQVQRRLGIFPANYVAPCRPAASP 106
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
S V + + +G G VY
Sbjct 107 APPPSRPSSPVHVAFERLELKELIGAGGFGQVYRATW----------------------- 143
Query 632 DRGQELRVVLKVLDPSHHD----IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
Q V +K A + A L + + H ++ + GVC++ P +V
Sbjct 144 ---QGQEVAVKAARQDPEQDAAAAAESVRREARLFAMLRHPNIIELRGVCLQQPHLCLVL 200
Query 688 EYVEHG-------------PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV--- 731
E+ G R +P + A Q+A + YL + V
Sbjct 201 EFARGGALNRALAAANAAPDPRAPGPRRARRIPPHVLVNWAVQIARGMLYLHEEAFVPIL 260
Query 732 HGNVCGRNILLARLGLAEGT-SPFIKLSDPGVGLG--ALSREERVERIPWLAPECLPGGA 788
H ++ NILL + + +K++D G+ ++ W+APE +
Sbjct 261 HRDLKSSNILLLEKIEHDDICNKTLKITDFGLAREWHRTTKMSTAGTYAWMAPEVIKSSL 320
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLT 845
S D W +G L E+ GE P + + + +P A L
Sbjct 321 --FSKGSDIWSYGVLLWELL-TGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLM 377
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
+C +P RPSF IL LT ++ + ++ + S D + ++ ++R +
Sbjct 378 KECWQQDPHIRPSFALILEQLTAIEGAVMTEMPQESFHSMQDDWKLEIQQMFDELRTKEK 437
Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
+ + E + +K + + ++E++IL
Sbjct 438 ELRSREEELTRAALQQKSQEEL-LKRREQQLAEREIDVLERELNIL 482
>sp|P92937|CIPKF_ARATH CBL-interacting serine/threonine-protein
kinase 15 OS=Arabidopsis thaliana OX=3702 GN=CIPK15 PE=1 SV=2
Length=421
Score = 225 bits (574), Expect = 2e-63, Method: Composition-based stats.
Identities = 62/269 (23%), Positives = 113/269 (42%), Gaps = 26/269 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHI 959
LG+G F KV Y + TG+ VA+K + + + K+EI +R L H +I
Sbjct 17 FLGQGTFAKV----YHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLLRHPNI 72
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
++ + + + VME+V G L + + + + QQ+ + + H++
Sbjct 73 VELHEVMATKSK--IYFVMEHVKGGELFNKVSTGKLREDVARKYFQQLVRAVDFCHSRGV 130
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
HRDL N+LLD +KI DFGL+ + + +P + APE + +
Sbjct 131 CHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPA-YVAPEVISRNGYD 189
Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+ +DVWS GV L+ LL + ++ L + + + E + P+
Sbjct 190 GFKADVWSCGVILFVLLAGYLPFRD---------------SNLMELYKKIGKAE-VKFPN 233
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L+K + + R + E ++
Sbjct 234 WLAPGAKRLLKRILDPNPNTRVSTEKIMK 262
Score = 182 bits (461), Expect = 2e-48, Method: Composition-based stats.
Identities = 57/287 (20%), Positives = 93/287 (32%), Gaps = 45/287 (16%)
Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---H 648
LGQGT VY R G V +KV+D
Sbjct 15 GKFLGQGTFAKVYHARHLKTGDS------------------------VAIKVIDKERILK 50
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ S M + H ++ +H V + V E+V+ G L + G +
Sbjct 51 VGMTEQIKREISAMRLLRHPNIVELHEVMATKSKIYFVMEHVKGGELFN--KVSTGKLRE 108
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
QQL A+ + ++ + H ++ N+LL G +K+SD G+ + S
Sbjct 109 DVARKYFQQLVRAVDFCHSRGVCHRDLKPENLLLDEHG-------NLKISDFGLSALSDS 161
Query 769 R------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
R ++APE + D W G L + G P + + E
Sbjct 162 RRQDGLLHTTCGTPAYVAPEVISRNGYD-GFKADVWSCGVIL-FVLLAGYLPFRDSNLME 219
Query 823 KE-HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ + + P P L + L P R S I++
Sbjct 220 LYKKIGKAEVKFPNWLAPGAKRLLKRILDPNPNTRVSTEKIMKSSWF 266
>sp|Q5W736|CIPKI_ORYSJ CBL-interacting protein kinase 18 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK18 PE=2 SV=1
Length=457
Score = 226 bits (577), Expect = 2e-63, Method: Composition-based stats.
Identities = 57/269 (21%), Positives = 107/269 (40%), Gaps = 26/269 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960
LG+G F KV Y N T + VA+K + D + K+EI +++ + H +I+
Sbjct 21 LGQGTFAKV----YHGRNIVTSQSVAIKVIDKDKIFKVGLMDQIKREISVMKLVRHPNIV 76
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ + + + V+EYV G L + + + + + QQ+ + + H++
Sbjct 77 QLYEVMATKSK--IYFVLEYVKGGELFNKVAKGRLKEDAARKYFQQLVSAVDFCHSRGVY 134
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
HRDL N+L+D + +KI DFGL+ + + +P + APE + +
Sbjct 135 HRDLKPENLLVDENGNLKITDFGLSALAESRRQDGLLHTTCGTPA-YVAPEVISRKGYDG 193
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
D WS GV L+ L+ Q ++ + + + E P
Sbjct 194 VKVDTWSCGVILFVLMAGYLPFQD---------------SNLMEMYRKIGKAE-FKCPAW 237
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPI 1168
+V L+ + R ++
Sbjct 238 FSSDVRKLVSRILDPNPRSRMPITKIMET 266
Score = 189 bits (479), Expect = 2e-50, Method: Composition-based stats.
Identities = 58/295 (20%), Positives = 99/295 (34%), Gaps = 45/295 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ + LGQGT VY G R+ V +KV
Sbjct 10 ILLRRYEIGKLLGQGTFAKVYHG------------------------RNIVTSQSVAIKV 45
Query 644 LDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
+D + S+M V H ++ ++ V + V EYV+ G L +
Sbjct 46 IDKDKIFKVGLMDQIKREISVMKLVRHPNIVQLYEVMATKSKIYFVLEYVKGGELFN--K 103
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+G + QQL SA+ + ++ + H ++ N+L+ G +K++D
Sbjct 104 VAKGRLKEDAARKYFQQLVSAVDFCHSRGVYHRDLKPENLLVDENG-------NLKITDF 156
Query 761 GVGLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ A SR ++APE + +D W G L + G P
Sbjct 157 GLSALAESRRQDGLLHTTCGTPAYVAPEVISRKGYD-GVKVDTWSCGVIL-FVLMAGYLP 214
Query 815 LQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
Q + E + + + P + L S+ L P R I+
Sbjct 215 FQDSNLMEMYRKIGKAEFKCPAWFSSDVRKLVSRILDPNPRSRMPITKIMETYWF 269
>sp|P92958|KIN11_ARATH SNF1-related protein kinase catalytic subunit
alpha KIN11 OS=Arabidopsis thaliana OX=3702 GN=KIN11
PE=1 SV=1
Length=512
Score = 228 bits (581), Expect = 2e-63, Method: Composition-based stats.
Identities = 77/292 (26%), Positives = 119/292 (41%), Gaps = 30/292 (10%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KAD 935
+ + + ++ K + LG G FGKV + + TG VA+K L +
Sbjct 1 MDHSSNRFGNNGVESILPNYKLGKTLGIGSFGKVKI----AEHVVTGHKVAIKILNRRKI 56
Query 936 CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHS 994
+ ++EI ILR H HII+ E + + +VMEYV G L DY+ +
Sbjct 57 KNMEMEEKVRREIKILRLFMHPHIIRQYEVIETTSD--IYVVMEYVKSGELFDYIVEKGR 114
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ + F QQI G+ Y H +HRDL N+LLD+ +KI DFGL+ + +G
Sbjct 115 LQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDG--- 171
Query 1055 YRVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
+ ++ SP + APE + + DVWS GV LY LL
Sbjct 172 HFLKTSCGSPN-YAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE--------- 221
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ L + ++ G P E L+ + R T +
Sbjct 222 ------NIPNLFKKIKGGI-YTLPSHLSSEARDLIPRMLIVDPVKRITIPEI 266
Score = 176 bits (445), Expect = 2e-45, Method: Composition-based stats.
Identities = 49/323 (15%), Positives = 96/323 (30%), Gaps = 39/323 (12%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP- 646
LG G+ V V G +V +K+L+
Sbjct 19 NYKLGKTLGIGSFGKVKIAEHVVTGH------------------------KVAIKILNRR 54
Query 647 --SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ ++ ++ H H+ + V + +V EYV+ G L ++ E+G
Sbjct 55 KIKNMEMEEKVRREIKILRLFMHPHIIRQYEVIETTSDIYVVMEYVKSGELFDYI-VEKG 113
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763
+ QQ+ S + Y +VH ++ N+LL + IK++D G+
Sbjct 114 RLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLD-------SRCNIKIADFGLSN 166
Query 764 --LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ + APE + G + +D W G L + P+
Sbjct 167 VMRDGHFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYALLCGTLPFDDENIPN 225
Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
+ + LP + L + L +P +R + I + ++
Sbjct 226 LFKKIKGGIYTLPSHLSSEARDLIPRMLIVDPVKRITIPEIRQHRWFQTHLPRYLAVSPP 285
Query 882 PDSPASDPTVFHKRYLKKIRDLG 904
+
Sbjct 286 DTVEQAKKINEEIVQEVVNMGFD 308
>sp|Q91048|PTK7_CHICK Inactive tyrosine-protein kinase 7 OS=Gallus
gallus OX=9031 GN=PTK7 PE=2 SV=1
Length=1051
Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats.
Identities = 87/298 (29%), Positives = 133/298 (45%), Gaps = 29/298 (10%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE-MVAVKALKADCGPQHR 941
A D F + L+ I LG G FG+V L D GE +V VK+L Q +
Sbjct 763 RHSARDKMHFPRSNLQTITTLGRGEFGEVFLAKAKGAEDAEGEALVLVKSL-QTRDEQLQ 821
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------P 991
+++E ++ L H ++++ G C + +V+EYV LG L+ +L
Sbjct 822 LDFRREAEMFGKLNHVNVVRLLGLCREAEPH--YMVLEYVDLGDLKQFLRISKSKDESLK 879
Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
+ + Q+ GM +L ++HRDLAARN L+ R VK+ L+K V
Sbjct 880 PQPLSTKHKVSLCTQVALGMEHLSNGRFVHRDLAARNCLVSAQRQVKVSALSLSKDVYNS 939
Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111
Y+ P+ W PE + E +F SDVWSFGV ++E+ T + +P L
Sbjct 940 EYYHF--RQAWIPLRWMPPEAVLEDEFSTKSDVWSFGVLMWEVFTQGEMPYAPLADDEVL 997
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
G+ G+ +LP+P+ CP + LM+ CW RP+F L L
Sbjct 998 AGLKSGKT-------------KLPQPEGCPSRLTKLMQRCWAPSPKDRPSFSELAAAL 1042
Score = 219 bits (557), Expect = 4e-57, Method: Composition-based stats.
Identities = 64/321 (20%), Positives = 117/321 (36%), Gaps = 44/321 (14%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
+ + +S + S + + ++ LG+G V+ + +
Sbjct 746 QEEVALTNLGSSSGASKRHSARDKMHFPRSNLQTITTLGRGEFGEVFLAKAKG------- 798
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
D E V++K L + L F A + +++H ++ + G+C
Sbjct 799 ------------AEDAEGEALVLVKSLQTRDEQLQLDFRREAEMFGKLNHVNVVRLLGLC 846
Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGH--------VPMAWKMVVAQQLASALSYLENKN 729
+ MV EYV+ G L +LR + + K+ + Q+A + +L N
Sbjct 847 REAEPHYMVLEYVDLGDLKQFLRISKSKDESLKPQPLSTKHKVSLCTQVALGMEHLSNGR 906
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECL 784
VH ++ RN L++ +K+S + + E R + W+ PE +
Sbjct 907 FVHRDLAARNCLVS-------AQRQVKVSALSLSKDVYNSEYYHFRQAWIPLRWMPPEAV 959
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQHRLPEPSCPQL 841
+ ST D W FG + E+ GE P + E + + PE +L
Sbjct 960 LE--DEFSTKSDVWSFGVLMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLPQPEGCPSRL 1017
Query 842 ATLTSQCLTYEPTQRPSFRTI 862
L +C P RPSF +
Sbjct 1018 TKLMQRCWAPSPKDRPSFSEL 1038
>sp|O22971|CIPKD_ARATH CBL-interacting serine/threonine-protein
kinase 13 OS=Arabidopsis thaliana OX=3702 GN=CIPK13 PE=1 SV=2
Length=502
Score = 228 bits (580), Expect = 3e-63, Method: Composition-based stats.
Identities = 68/268 (25%), Positives = 113/268 (42%), Gaps = 26/268 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960
LG G F KV L N +GE VA+K + + + K+EI ILR + H +I+
Sbjct 63 LGHGSFAKVYL----ARNIHSGEDVAIKVIDKEKIVKSGLAGHIKREISILRRVRHPYIV 118
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ + + +VMEYV G L + + R + + QQ+ +A+ H++
Sbjct 119 HLLEVMATKTK--IYIVMEYVRGGELYNTVARGRLREGTARRYFQQLISSVAFCHSRGVY 176
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF-Y 1079
HRDL N+LLD+ VK+ DFGL+ V E + + + + APE L +
Sbjct 177 HRDLKLENLLLDDKGNVKVSDFGLS-VVSEQLKQEGICQTFCGTPAYLAPEVLTRKGYEG 235
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS GV L+ L+ +L + + +G + P
Sbjct 236 AKADIWSCGVILFVLMAGYLPFDD---------------KNILVMYTKIYKG-QFKCPKW 279
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
E+ L+ +T R T ++
Sbjct 280 FSPELARLVTRMLDTNPDTRITIPEIMK 307
Score = 181 bits (458), Expect = 3e-47, Method: Composition-based stats.
Identities = 59/332 (18%), Positives = 106/332 (32%), Gaps = 43/332 (13%)
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
++P + + + + LG G+ VY R G
Sbjct 32 TNKETSTPESPRSPRTPQGSILMDKYEIGKLLGHGSFAKVYLARNIHSGED--------- 82
Query 624 EDPLVPGRDRGQELRVVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680
V +KV+D +A S++ +V H ++ + V
Sbjct 83 ---------------VAIKVIDKEKIVKSGLAGHIKREISILRRVRHPYIVHLLEVMATK 127
Query 681 PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNI 740
+ +V EYV G L RG + QQL S++++ ++ + H ++ N+
Sbjct 128 TKIYIVMEYVRGGELYN--TVARGRLREGTARRYFQQLISSVAFCHSRGVYHRDLKLENL 185
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTA 794
LL G +K+SD G+ + + + +LAPE L
Sbjct 186 LLDDKG-------NVKVSDFGLSVVSEQLKQEGICQTFCGTPAYLAPEVLTRKGYE-GAK 237
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854
D W G L + Y+ Q + P+ P+LA L ++ L P
Sbjct 238 ADIWSCGVILFVLMAGYLPFDDKNILVMYTKIYKGQFKCPKWFSPELARLVTRMLDTNPD 297
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
R + I++ + N
Sbjct 298 TRITIPEIMKHRWFKKGFKHVKFYIENDKLCR 329
>sp|Q9V3Q6|M3K7_DROME Mitogen-activated protein kinase kinase
kinase 7 OS=Drosophila melanogaster OX=7227 GN=Tak1 PE=2 SV=1
Length=678
Score = 232 bits (592), Expect = 3e-63, Method: Composition-based stats.
Identities = 72/284 (25%), Positives = 125/284 (44%), Gaps = 38/284 (13%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G +G V + ++VAVK A + ++E+ L + H +II
Sbjct 24 KVGHGSYGVVCKAVWR------DKLVAVKEFFASA---EQKDIEKEVKQLSRVKHPNIIA 74
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQ- 1017
G +++ L+ME+ GSL ++L + + LA + +A+Q EG+AYLHA
Sbjct 75 LHGI--SSYQQATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMT 132
Query 1018 --HYIHRDLAARNVLLDNDR-LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRD+ N+LL N +KI DFG + + + W APE +
Sbjct 133 PKPLIHRDVKPLNLLLTNKGRNLKICDFG------TVADKSTMMTNNRGSAAWMAPEVFE 186
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
K+ D++S+ + L+E+L+ +G + + +GER
Sbjct 187 GSKYTEKCDIFSWAIVLWEVLSRKQPF--------------KGIDNAYTIQWKIYKGERP 232
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
P CP + LM CW+T RP+ + ++ ++ + + Y G
Sbjct 233 PLLTTCPKRIEDLMTACWKTVPEDRPSMQYIVGVMHEIVKDYTG 276
Score = 201 bits (512), Expect = 6e-53, Method: Composition-based stats.
Identities = 62/305 (20%), Positives = 111/305 (36%), Gaps = 45/305 (15%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
T +L L VD EIT +G G+ V + R +
Sbjct 3 TASLDALQAAYVDFSEITLREKVGHGSYGVVCKAVWRDK--------------------- 41
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
V +K S + + +S+V H ++ +HG+ ++ E+ E
Sbjct 42 -----LVAVKEFFASAEQKDIE--KEVKQLSRVKHPNIIALHGISSYQQATYLIMEFAEG 94
Query 693 GPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLA 748
G L +L + + +A M A+Q A L+YL K L+H +V N+LL G
Sbjct 95 GSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMTPKPLIHRDVKPLNLLLTNKG-- 152
Query 749 EGTSPFIKLSDPG-VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+ D G V + W+APE G + + D + + L E+
Sbjct 153 ----RNLKICDFGTVADKSTMMTNNRGSAAWMAPEVFEG--SKYTEKCDIFSWAIVLWEV 206
Query 808 CFDGEAPLQSRSPS---EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ P + + + + + + L ++ L + C P RPS + I+
Sbjct 207 LSR-KQPFKGIDNAYTIQWKIYKGERPPLLTTCPKRIEDLMTACWKTVPEDRPSMQYIVG 265
Query 865 DLTRL 869
+ +
Sbjct 266 VMHEI 270
>sp|Q0PW40|CRK13_ARATH Cysteine-rich receptor-like protein kinase
13 OS=Arabidopsis thaliana OX=3702 GN=CRK13 PE=2 SV=1
Length=673
Score = 232 bits (591), Expect = 3e-63, Method: Composition-based stats.
Identities = 70/296 (24%), Positives = 118/296 (40%), Gaps = 23/296 (8%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
LG G G V G+ +AVK L ++ Q + +K
Sbjct 347 QYKFKTIETATNNFSERLGHGGSGHVFKGRL-----PDGKEIAVKRL-SEKTEQSKKEFK 400
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLL 1001
E+ ++ L H ++++ G +GE+ + +V EY+P SL L + + +
Sbjct 401 NEVVLVAKLQHRNLVRLLG-FSVKGEEKI-IVYEYLPNRSLDYILFDPTKQGELDWKKRY 458
Query 1002 LFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
G+ YLH IHRDL A N+LLD K+ DFG A+
Sbjct 459 KIIGGTARGILYLHQDSQPTIIHRDLKAGNILLDAHMNPKVADFGTARIFGMDQSVAITA 518
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQ 1116
+P + APE ++ +F SDV+S+GV + E++ S SP F+ +
Sbjct 519 NAAGTP-GYMAPEYMELGEFSMKSDVYSYGVLVLEIICGKRNTSFSSPVQNFVTYVWRLW 577
Query 1117 GQMTVLRLTEL-LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
T L L + + + + H+ C + E + RP F ++ +L +
Sbjct 578 KSGTPLNLVDATIAENYK----SEEVIRCIHIALLCVQEEPTDRPDFSIIMSMLTS 629
Score = 216 bits (550), Expect = 6e-58, Method: Composition-based stats.
Identities = 65/341 (19%), Positives = 112/341 (33%), Gaps = 69/341 (20%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
+ + + + S R+L F ++ LG G +V++GRL
Sbjct 326 KEKPYQEVELNQTGITSVRSLQYK---FKTIETATNNFSERLGHGGSGHVFKGRLPDGK- 381
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
+ +K L F L++++ H +L +
Sbjct 382 ------------------------EIAVKRLSEKTEQSKKEFKNEVVLVAKLQHRNLVRL 417
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN-- 729
G V+G E I+V EY+ + LD L + W + + A + YL +
Sbjct 418 LGFSVKGEEKIIVYEYLPNRSLDYILFDPTKQGELDWKKRYKIIGGTARGILYLHQDSQP 477
Query 730 -LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPE 782
++H ++ NILL K++D G ++APE
Sbjct 478 TIIHRDLKAGNILLD-------AHMNPKVADFGTARIFGMDQSVAITANAAGTPGYMAPE 530
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP--- 839
+ G S D + +G +LEI G+ SP ++F RL + P
Sbjct 531 YMELG--EFSMKSDVYSYGVLVLEIIC-GKRNTSFSSP--VQNFVTYVWRLWKSGTPLNL 585
Query 840 ---------------QLATLTSQCLTYEPTQRPSFRTILRD 865
+ + C+ EPT RP F I+
Sbjct 586 VDATIAENYKSEEVIRCIHIALLCVQEEPTDRPDFSIIMSM 626
>sp|Q869W6|MYLKG_DICDI Probable myosin light chain kinase DDB_G0275057
OS=Dictyostelium discoideum OX=44689 GN=DDB_G0275057
PE=3 SV=1
Length=349
Score = 222 bits (566), Expect = 3e-63, Method: Composition-based stats.
Identities = 74/275 (27%), Positives = 109/275 (40%), Gaps = 31/275 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHII 960
+LG G F V + T T + VA+K + K +H ++EIDI++ + HE+++
Sbjct 61 ELGRGAFSVVR----EGTRKTTSDKVALKYIEKKFVKKKHIEQLRREIDIMKKVKHENVL 116
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLR-DYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
K E + L LVME V G L + R S +Q+C G+ YLH+Q
Sbjct 117 SLKEIFE--SDSHLTLVMELVTGGELFYKIVERGSFTEKGARNVVRQVCAGVEYLHSQGI 174
Query 1020 IHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
HRDL N+L + D +KI DFGL+K G E + APE L
Sbjct 175 AHRDLKPENLLCNGEGEDMTIKIADFGLSKIFGTGEAL----ETSCGTPDYVAPEVLTGG 230
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+ A D+WS GV Y LL L ++L P
Sbjct 231 SYDNAVDMWSIGVITYILLCGFPPF--------------YASSQNLLFEKILTADYDFPE 276
Query 1137 PD--KCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
P+ ++N + R T + + L
Sbjct 277 PEWTHVSEHAKAFIRNLIVKDPDQRHTAKQCLDDL 311
Score = 170 bits (430), Expect = 5e-45, Method: Composition-based stats.
Identities = 65/343 (19%), Positives = 114/343 (33%), Gaps = 50/343 (15%)
Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLS--------- 593
CF+ + +P T+ + T + +DQ +I+Q +
Sbjct 2 GCFNSKEAGAGRPKTTTQQQQQATPEPTVTTAEVRADEKISMDQ-DISQGNVEDFYVVGK 60
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDI 651
LG+G + V EG + +V LK ++
Sbjct 61 ELGRGAFSVVREGTRKTTSD------------------------KVALKYIEKKFVKKKH 96
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711
+M +V H ++ + + +V E V G L + ERG
Sbjct 97 IEQLRREIDIMKKVKHENVLSLKEIFESDSHLTLVMELVTGGELFYKI-VERGSFTEKGA 155
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---GALS 768
V +Q+ + + YL ++ + H ++ N+L EG IK++D G+ +
Sbjct 156 RNVVRQVCAGVEYLHSQGIAHRDLKPENLLCN----GEGEDMTIKIADFGLSKIFGTGEA 211
Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
E ++APE L GG S A+D W G + S E
Sbjct 212 LETSCGTPDYVAPEVLTGG--SYDNAVDMWSIGVITYILLCGFPPFYASSQNLLFEKILT 269
Query 829 RQHRLPEPSCPQLAT----LTSQCLTYEPTQRPSFRTILRDLT 867
+ PEP ++ + +P QR + + L DL
Sbjct 270 ADYDFPEPEWTHVSEHAKAFIRNLIVKDPDQRHTAKQCLDDLW 312
>sp|O64556|Y2923_ARATH Putative leucine-rich repeat receptor-like
serine/threonine-protein kinase At2g19230 OS=Arabidopsis
thaliana OX=3702 GN=At2g19230 PE=1 SV=3
Length=877
Score = 236 bits (601), Expect = 3e-63, Method: Composition-based stats.
Identities = 66/313 (21%), Positives = 125/313 (40%), Gaps = 17/313 (5%)
Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE 925
+ + + + + R LG+G FGKV GE
Sbjct 538 FWQFKKRQQSVKTGPLDTKRYYKYSEIVEITNNFERVLGQGGFGKVYYGVLR------GE 591
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
VA+K L Q ++ E+++L ++H+++I G C + + + L+ EY+ G+
Sbjct 592 QVAIKMLSK-SSAQGYKEFRAEVELLLRVHHKNLIALIGYCHEGDQ--MALIYEYIGNGT 648
Query 986 LRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKI 1039
L DYL + + + L + +G+ YLH +HRD+ N+L++ KI
Sbjct 649 LGDYLSGKNSSILSWEERLQISLDAAQGLEYLHNGCKPPIVHRDVKPTNILINEKLQAKI 708
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGL+++ + V + + + PE +F SDV+SFGV L E++T
Sbjct 709 ADFGLSRSFTLEGDSQ-VSTEVAGTIGYLDPEHYSMQQFSEKSDVYSFGVVLLEVITGQP 767
Query 1100 S-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
S+S + + ++ + +++ ++ + C
Sbjct 768 VISRSRTEENRHISDRVSLMLSKGDIKSIVDPKLGERFNAGLAWKITEVALACASESTKT 827
Query 1159 RPTFENLIPILKT 1171
R T ++ LK
Sbjct 828 RLTMSQVVAELKE 840
Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats.
Identities = 60/268 (22%), Positives = 96/268 (36%), Gaps = 47/268 (18%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+ + + LGQG VY G LR E
Sbjct 557 RYYKYSEIVEITNNFERVLGQGGFGKVYYGVLRGE------------------------- 591
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+V +K+L S F L+ +V H +L + G C G + ++ EY+ +G L
Sbjct 592 -QVAIKMLSKSSAQGYKEFRAEVELLLRVHHKNLIALIGYCHEGDQMALIYEYIGNGTLG 650
Query 697 VWLRRERGH-VPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTS 752
+L + + ++ ++ A L YL N +VH +V NIL+ A
Sbjct 651 DYLSGKNSSILSWEERLQISLDAAQGLEYLHNGCKPPIVHRDVKPTNILINEKLQA---- 706
Query 753 PFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
K++D G+ + E I +L PE S D + FG LLE
Sbjct 707 ---KIADFGLSRSFTLEGDSQVSTEVAGTIGYLDPEHYSM--QQFSEKSDVYSFGVVLLE 761
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLP 834
+ P+ SRS +E+ + L
Sbjct 762 VITG--QPVISRSRTEENRHISDRVSLM 787
>sp|Q9SXB3|Y1112_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g11280 OS=Arabidopsis thaliana OX=3702
GN=At1g11280 PE=2 SV=1
Length=820
Score = 235 bits (599), Expect = 3e-63, Method: Composition-based stats.
Identities = 74/312 (24%), Positives = 123/312 (39%), Gaps = 27/312 (9%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
+ LG+G FG V D +AVK L + G Q
Sbjct 492 FFEMNTIRAATNNFNVSNKLGQGGFGPVYKGTLSDKKD-----IAVKRLSSSSG-QGTEE 545
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQ 999
+ EI ++ L H ++++ GCC D EK L+ E++ SL +L + I +
Sbjct 546 FMNEIKLISKLQHRNLVRLLGCCIDGEEK--LLIYEFLVNKSLDTFLFDLTLKLQIDWPK 603
Query 1000 LLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
Q + G+ YLH IHRDL N+LLD+ KI DFGLA+ +G ++
Sbjct 604 RFNIIQGVSRGLLYLHRDSCMRVIHRDLKVSNILLDDKMNPKISDFGLARMF-QGTQHQD 662
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIA 1115
+ + +PE F SD+++FGV L E+++ SS + L+G A
Sbjct 663 NTRKVVGTLGYMSPEYAWTGMFSEKSDIYAFGVLLLEIISGKKISSFCCGEEGKTLLGHA 722
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPC------EVYHLMKNCWETEASFRPTFENLIPIL 1169
+LL+ C + C + +A RP ++ ++
Sbjct 723 WECWLETGGVDLLDE----DISSSCSPVEVEVARCVQIGLLCIQQQAVDRPNIAQVVTMM 778
Query 1170 KTVHEKYQGQAP 1181
+ + + + P
Sbjct 779 TSATDLPRPKQP 790
Score = 222 bits (566), Expect = 5e-59, Method: Composition-based stats.
Identities = 52/250 (21%), Positives = 93/250 (37%), Gaps = 45/250 (18%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L +++ R + LGQG VY+G L +
Sbjct 490 LTFFEMNTIRAATNNFNVSNKLGQGGFGPVYKGTLSDKKD-------------------- 529
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ +K L S F L+S++ H +L + G C+ G E +++ E++ +
Sbjct 530 -----IAVKRLSSSSGQGTEEFMNEIKLISKLQHRNLVRLLGCCIDGEEKLLIYEFLVNK 584
Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLA 748
LD +L + + W + + Q ++ L YL ++H ++ NILL
Sbjct 585 SLDTFLFDLTLKLQIDWPKRFNIIQGVSRGLLYLHRDSCMRVIHRDLKVSNILLDDK--- 641
Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
K+SD G+ + + V + +++PE G S D + FG
Sbjct 642 ----MNPKISDFGLARMFQGTQHQDNTRKVVGTLGYMSPEYAWTGM--FSEKSDIYAFGV 695
Query 803 TLLEICFDGE 812
LLEI +
Sbjct 696 LLLEIISGKK 705
>sp|G5EBZ8|ARK1_CAEEL Ack-related non-receptor tyrosine kinase
OS=Caenorhabditis elegans OX=6239 GN=ark-1 PE=2 SV=1
Length=1043
Score = 238 bits (606), Expect = 3e-63, Method: Composition-based stats.
Identities = 95/294 (32%), Positives = 151/294 (51%), Gaps = 23/294 (8%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
+ +D V + ++LG+G FG V + + VAVK + +D S
Sbjct 99 NQDDNDHHVIPIEKITLCKELGQGEFGSVWQAGWKNSAGSDVIQVAVKCVGSDKLLATSS 158
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLA 998
+ QE I+ + HEH+++ G D K + LV E GSL + L R S +
Sbjct 159 SFLQEAAIMTRMRHEHVVRLYGVVLDT--KKIMLVSELATCGSLLECLHKPALRDSFPVH 216
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV- 1057
L +A+QI GM+YL Q IHRDLAARNVL+ + +LVKI DFGL++++ G +YYR
Sbjct 217 VLCDYAEQIAMGMSYLELQRLIHRDLAARNVLVFSPKLVKISDFGLSRSLGIGEDYYRSE 276
Query 1058 -REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
+ P+ W APEC+ KF SDVW++GVT++E+ ++ + +
Sbjct 277 FTPNLKLPIAWCAPECINFLKFTSKSDVWAYGVTIWEMFSYGE--------------MPW 322
Query 1117 GQMTVLRLTELLERGER-LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ ++ EL++R + L RP CP ++Y ++K W + RPTF +++
Sbjct 323 KGRSGAQILELVDRKKELLTRPKACPEDIYDMLKETWTHQVQDRPTFSDIVAKF 376
Score = 217 bits (553), Expect = 2e-56, Method: Composition-based stats.
Identities = 69/338 (20%), Positives = 136/338 (40%), Gaps = 44/338 (13%)
Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
+ S N H + ++IT LGQG +V++ + D
Sbjct 92 KTSNSVANQDDNDHHVIPIEKITLCKELGQGEFGSVWQAGWKNSAGSDV----------- 140
Query 628 VPGRDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
++V +K + + +F + A++M+++ H H+ ++GV + + ++V
Sbjct 141 ---------IQVAVKCVGSDKLLATSSSFLQEAAIMTRMRHEHVVRLYGVVLDTKKIMLV 191
Query 687 TEYVEHGPLDVWLRRE--RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+E G L L + R P+ A+Q+A +SYLE + L+H ++ RN+L+
Sbjct 192 SELATCGSLLECLHKPALRDSFPVHVLCDYAEQIAMGMSYLELQRLIHRDLAARNVLV-- 249
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER---------IPWLAPECLPGGANSLSTAM 795
+ +K+SD G+ E+ I W APEC+ ++
Sbjct 250 -----FSPKLVKISDFGLSRSLGIGEDYYRSEFTPNLKLPIAWCAPECI--NFLKFTSKS 302
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL---PEPSCPQLATLTSQCLTYE 852
D W +G T+ E+ GE P + RS ++ R+ L P+ + + + T++
Sbjct 303 DVWAYGVTIWEMFSYGEMPWKGRSGAQILELVDRKKELLTRPKACPEDIYDMLKETWTHQ 362
Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
RP+F I+ + ++ V+ +
Sbjct 363 VQDRPTFSDIVAKFPERRAQSVRAVVDCKDSAADHLHF 400
>sp|Q5JLS2|CIPKC_ORYSJ CBL-interacting protein kinase 12 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK12 PE=1 SV=1
Length=540
Score = 228 bits (582), Expect = 3e-63, Method: Composition-based stats.
Identities = 64/268 (24%), Positives = 109/268 (41%), Gaps = 26/268 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960
LG+G F KV Y + T E VA+K L + + K+EI++LR + H +I+
Sbjct 52 LGQGSFAKV----YQARHLETDECVAIKVLDKEKAVKGGMVHLVKREINVLRRVRHPNIV 107
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ + + + VMEYV G L + + + + QQ+ + + HA+
Sbjct 108 QLFEVMASKTK--IYFVMEYVRGGELFSRVSKGRLREDTARRYFQQLVSAVDFCHARGVF 165
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
HRDL N+L+D + +K+ DFGLA + + +P + APE L+ +
Sbjct 166 HRDLKPENLLVDENGDLKVSDFGLAAGPDQFDPDGLLHTFCGTPA-YVAPEVLRRRGYDG 224
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS GV L+ L+ ++ L + GE P
Sbjct 225 AKADIWSCGVILFALMAGYLPFHD---------------HNIMVLYRKIYNGE-FRCPRW 268
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ L+ + R T +I
Sbjct 269 FSKDFTRLITRLLDANPKTRITVPEIIE 296
Score = 187 bits (475), Expect = 3e-49, Method: Composition-based stats.
Identities = 53/308 (17%), Positives = 91/308 (30%), Gaps = 43/308 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ LGQG+ VY+ R V +KVLD
Sbjct 45 KYELGRVLGQGSFAKVYQARHLETDEC------------------------VAIKVLDKE 80
Query 648 H---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ +++ +V H ++ + V + V EYV G L R +G
Sbjct 81 KAVKGGMVHLVKREINVLRRVRHPNIVQLFEVMASKTKIYFVMEYVRGGELFS--RVSKG 138
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ QQL SA+ + + + H ++ N+L+ G +K+SD G+
Sbjct 139 RLREDTARRYFQQLVSAVDFCHARGVFHRDLKPENLLVDENGD-------LKVSDFGLAA 191
Query 765 GALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
G + ++APE L D W G L +
Sbjct 192 GPDQFDPDGLLHTFCGTPAYVAPEVLRRRGYD-GAKADIWSCGVILFALMAGYLPFHDHN 250
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
Y + R P L ++ L P R + I+ + +
Sbjct 251 IMVLYRKIYNGEFRCPRWFSKDFTRLITRLLDANPKTRITVPEIIESDWFKKGYKPVKFY 310
Query 879 TVNPDSPA 886
+
Sbjct 311 IEDDKLYN 318
>sp|Q01974|ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor
ROR2 OS=Homo sapiens OX=9606 GN=ROR2 PE=1 SV=2
Length=943
Score = 236 bits (603), Expect = 3e-63, Method: Composition-based stats.
Identities = 83/349 (24%), Positives = 140/349 (40%), Gaps = 39/349 (11%)
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899
L L C + + + + + + + + ++
Sbjct 420 CLFFLVCMCRNKQKASASTP----QRRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRF 475
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTG-EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+ +LGE FGKV G + VA+K LK R ++ E + L H +
Sbjct 476 MEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPN 535
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----------------RHSIGLAQLL 1001
++ G ++ L ++ Y G L ++L + ++ +
Sbjct 536 VVCLLGVVTK--DQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFV 593
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
QI GM YL + H +H+DLA RNVL+ + VKI D GL + V +YY++ +
Sbjct 594 HLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVY-AADYYKLLGNS 652
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
P+ W APE + KF SD+WS+GV L+E+ ++ +
Sbjct 653 LLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQ--------------PYCGYSN 698
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ E++ + LP PD CP VY LM CW S RP F+++ L+
Sbjct 699 QDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 747
Score = 229 bits (583), Expect = 1e-60, Method: Composition-based stats.
Identities = 69/340 (20%), Positives = 125/340 (37%), Gaps = 61/340 (18%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
RR + P + + ++ Q + + + LG+ VY+G
Sbjct 441 RRQLMASPSQDMEMPLIN---------QHKQAKLKEISLSAVRFMEELGEDRFGKVYKGH 491
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVS 666
L G+ Q V +K L D + + F A L +++
Sbjct 492 LFGPAPGE-------------------QTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQ 532
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---------------RRERGHVPMAWK 711
H ++ + GV + M+ Y HG L +L R + +
Sbjct 533 HPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDF 592
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771
+ + Q+A+ + YL + ++VH ++ RN+L+ +K+SD G+ + +
Sbjct 593 VHLVAQIAAGMEYLSSHHVVHKDLATRNVLV-------YDKLNVKISDLGLFREVYAADY 645
Query 772 R------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
+ I W+APE + G S+ D W +G L E+ G P S +
Sbjct 646 YKLLGNSLLPIRWMAPEAIMYGKFSID--SDIWSYGVVLWEVFSYGLQPYCGYSNQDVVE 703
Query 826 FYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTIL 863
+ + LP P CP + L +C P++RP F+ I
Sbjct 704 MIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIH 743
>sp|Q9CAL2|CRK3_ARATH Cysteine-rich receptor-like protein kinase
3 OS=Arabidopsis thaliana OX=3702 GN=CRK3 PE=2 SV=1
Length=646
Score = 231 bits (589), Expect = 3e-63, Method: Composition-based stats.
Identities = 72/309 (23%), Positives = 121/309 (39%), Gaps = 18/309 (6%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
+ + Y LG+G G V G+ VAVK L Q
Sbjct 310 CFSYENLERATDYFSDKNKLGQGGSGSVYKGVL-----TNGKTVAVKRL-FFNTKQWVDH 363
Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ 999
+ E++++ + H++++K GC E LV EY+ SL DYL + A+
Sbjct 364 FFNEVNLISQVDHKNLVKLLGCSITGPES--LLVYEYIANQSLHDYLFVRKDVQPLNWAK 421
Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
EGMAYLH + IHRD+ N+LL++D +I DFGLA+ PE +
Sbjct 422 RFKIILGTAEGMAYLHEESNLRIIHRDIKLSNILLEDDFTPRIADFGLARLFPEDKTHIS 481
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
G + + APE + K +DV+SFGV + E++T ++ ++
Sbjct 482 TAIAG--TLGYMAPEYVVRGKLTEKADVYSFGVLMIEVITGKRNNAF-VQDAGSILQSVW 538
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
+ E ++ + + C + RP ++ ++K E +
Sbjct 539 SLYRTSNVEEAVDPILGDNFNKIEASRLLQIGLLCVQAAFDQRPAMSVVVKMMKGSLEIH 598
Query 1177 QGQAPSVFS 1185
P +
Sbjct 599 TPTQPPFLN 607
Score = 216 bits (551), Expect = 4e-58, Method: Composition-based stats.
Identities = 59/328 (18%), Positives = 120/328 (37%), Gaps = 50/328 (15%)
Query 499 SLRLRKFPIEQQDGAFVLEGWGR----SFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554
+R + + + G + + +++ +L F L++ +
Sbjct 231 GCYMRFSTQKFYNNSGNSTSDGNGGHNHLGVILAVTSSVVAFVLLVSAAGFLLKKRHAKK 290
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
E L + A+ L S + R + + LGQG +VY+G L +
Sbjct 291 QREKKQLGSL-FMLANKSNLCFSYENLER-ATDYFSDKNKLGQGGSGSVYKGVLTNGKT- 347
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
V +K L + F+ +L+SQV H +L +
Sbjct 348 ------------------------VAVKRLFFNTKQWVDHFFNEVNLISQVDHKNLVKLL 383
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---N 729
G + GPE+++V EY+ + L +L + P+ W + + A ++YL +
Sbjct 384 GCSITGPESLLVYEYIANQSLHDYLFVRKDVQPLNWAKRFKIILGTAEGMAYLHEESNLR 443
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECL 784
++H ++ NILL +++D G+ + + + ++APE +
Sbjct 444 IIHRDIKLSNILL-------EDDFTPRIADFGLARLFPEDKTHISTAIAGTLGYMAPEYV 496
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGE 812
G L+ D + FG ++E+
Sbjct 497 VRG--KLTEKADVYSFGVLMIEVITGKR 522
>sp|Q6P9R2|OXSR1_MOUSE Serine/threonine-protein kinase OSR1 OS=Mus
musculus OX=10090 GN=Oxsr1 PE=1 SV=1
Length=527
Score = 228 bits (581), Expect = 3e-63, Method: Composition-based stats.
Identities = 71/293 (24%), Positives = 121/293 (41%), Gaps = 30/293 (10%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
P ++ + +G G V P E VA+K + + +EI
Sbjct 9 PWSINRDDYELQEVIGSGATAVVQAAYCAPKK----ERVAIKRINLEKCQTSMDELLKEI 64
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQ 999
+ +H +I+ Y + E L LVM+ + GS+ D + +
Sbjct 65 QAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEPT 122
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--V 1057
+ +++ EG+ YLH IHRD+ A N+LL D V+I DFG++ + G + R V
Sbjct 123 IATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKV 182
Query 1058 REDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQS-PPTK--FLELIG 1113
R+ W APE +++ + + +D+WSFG+T EL T PP K L L
Sbjct 183 RKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQN 242
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
T ++ E+L++ + ++ C + + RPT L+
Sbjct 243 DPPSLETGVQDKEMLKKYGK---------SFRKMISLCLQKDPEKRPTAAELL 286
Score = 177 bits (449), Expect = 6e-46, Method: Composition-based stats.
Identities = 53/315 (17%), Positives = 102/315 (32%), Gaps = 61/315 (19%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+++ + +G G V P ++R V +
Sbjct 10 WSINRDDYELQEVIGSGATAVV-------------------QAAYCAPKKER-----VAI 45
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K ++ ++ + MSQ H ++ + V E +V + + G + ++
Sbjct 46 KRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIK 105
Query 701 R-------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
+ G + + +++ L YL +H +V NILL G
Sbjct 106 HIVAKGEHKSGVLDEPTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG------- 158
Query 754 FIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
++++D GV + R+ V W+APE + D W FG T
Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKADIWSFGITA 217
Query 805 LEICFDGEAPLQSRSPSEKEHFY-----------QRQHRLPEPSCPQLATLTSQCLTYEP 853
+E+ G AP P + + + + + S CL +P
Sbjct 218 IELA-TGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDP 276
Query 854 TQRPSFRTILRDLTR 868
+RP+ +LR
Sbjct 277 EKRPTAAELLRHKFF 291
>sp|Q66GN2|LRK64_ARATH Lectin-domain containing receptor kinase
VI.4 OS=Arabidopsis thaliana OX=3702 GN=LECRK64 PE=2 SV=1
Length=691
Score = 232 bits (591), Expect = 4e-63, Method: Composition-based stats.
Identities = 76/384 (20%), Positives = 136/384 (35%), Gaps = 29/384 (8%)
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857
W F GE PL + + ++ L T
Sbjct 270 WSFA-------SGGEHPLAAMLDISQLPPPPPNKAKKRGYNGKVIALIVALSTVISIMLV 322
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL-GEGHFGKVSLYCY 916
+ R+Q + + ++ ++ K + G G FG V
Sbjct 323 LLFLFMMYKKRMQQEEILEDWEIDHPHRFRYRDLYKATEGFKENRVVGTGGFGIVYRGNI 382
Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976
++D +AVK + + Q + EI+ L L H++++ +G C+ + + L L
Sbjct 383 RSSSD----QIAVKKITPN-SMQGVREFVAEIESLGRLRHKNLVNLQGWCKHRND--LLL 435
Query 977 VMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAAR 1027
+ +Y+P GSL L + A+ I G+ YLH + IHRD+
Sbjct 436 IYDYIPNGSLDSLLYSKPRRSGAVLSWNARFQIAKGIASGLLYLHEEWEQIVIHRDVKPS 495
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
NVL+D+D ++GDFGLA+ G + + APE + ASDV++F
Sbjct 496 NVLIDSDMNPRLGDFGLARLYERGS--QSCTTVVVGTIGYMAPELARNGNSSSASDVFAF 553
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
GV L E+++ + S + + Q + ++ + +
Sbjct 554 GVLLLEIVSGRKPTDSGTFFIADWVMELQAS---GEILSAIDPRLGSGYDEGEARLALAV 610
Query 1148 MKNCWETEASFRPTFENLIPILKT 1171
C + RP ++ L
Sbjct 611 GLLCCHHKPESRPLMRMVLRYLNR 634
Score = 206 bits (523), Expect = 3e-54, Method: Composition-based stats.
Identities = 60/306 (20%), Positives = 105/306 (34%), Gaps = 58/306 (19%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ + +G G VY G +R ++ +K +
Sbjct 359 ATEGFKENRVVGTGGFGIVYRGNIRSSSD------------------------QIAVKKI 394
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL----R 700
P+ F + ++ H +L + G C + +++ +Y+ +G LD L R
Sbjct 395 TPNSMQGVREFVAEIESLGRLRHKNLVNLQGWCKHRNDLLLIYDYIPNGSLDSLLYSKPR 454
Query 701 RERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
R + + +A+ +AS L YL + ++H +V N+L+ + +L
Sbjct 455 RSGAVLSWNARFQIAKGIASGLLYLHEEWEQIVIHRDVKPSNVLID-------SDMNPRL 507
Query 758 SDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
D G+ V I ++APE G + S+A D + FG LLEI +
Sbjct 508 GDFGLARLYERGSQSCTTVVVGTIGYMAPELARNGNS--SSASDVFAFGVLLLEIVSGRK 565
Query 813 A---------PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ----CLTYEPTQRPSF 859
+ E RL A L C ++P RP
Sbjct 566 PTDSGTFFIADWVMELQASGEILSAIDPRLGSGYDEGEARLALAVGLLCCHHKPESRPLM 625
Query 860 RTILRD 865
R +LR
Sbjct 626 RMVLRY 631
>sp|Q7ZUQ3|STK3_DANRE Serine/threonine-protein kinase 3 OS=Danio
rerio OX=7955 GN=stk3 PE=2 SV=1
Length=492
Score = 227 bits (578), Expect = 4e-63, Method: Composition-based stats.
Identities = 64/268 (24%), Positives = 110/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V + + +G++VA+K + + Q +EI I++ +++K
Sbjct 31 KLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQ---EIIKEISIMQQCDSPYVVK 83
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ + +G+ YLH
Sbjct 84 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLKSTLKGLEYLHFMRK 141
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 142 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 198
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 199 CVADIWSLGITSIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEH 245
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ +K C R T L+
Sbjct 246 WSDDFTDFVKKCLVKNPEQRATATQLLQ 273
Score = 201 bits (510), Expect = 3e-54, Method: Composition-based stats.
Identities = 58/314 (18%), Positives = 101/314 (32%), Gaps = 44/314 (14%)
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
M + + LS+ S + ++ L LG+G+ +V++ + G
Sbjct 1 MEHSVPKNKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQ---------- 50
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
V +K + + S+M Q ++ +G + +
Sbjct 51 --------------VVAIKQVPVESD--LQEIIKEISIMQQCDSPYVVKYYGSYFKNTDL 94
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+V EY G + +R + V + L YL +H ++ NILL
Sbjct 95 WIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLKSTLKGLEYLHFMRKIHRDIKAGNILLN 154
Query 744 RLGLAEGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWG 799
G KL+D GV R + W+APE + + D W
Sbjct 155 TEG-------HAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWS 205
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQ 855
G T +E+ +G+ P P R PE +CL P Q
Sbjct 206 LGITSIEMA-EGKPPYADIHPMRAIFMIPTNPPPTFRKPEHWSDDFTDFVKKCLVKNPEQ 264
Query 856 RPSFRTILRDLTRL 869
R + +L+ +
Sbjct 265 RATATQLLQHPFIV 278
>sp|Q9ZR79|LRK57_ARATH L-type lectin-domain containing receptor
kinase V.7 OS=Arabidopsis thaliana OX=3702 GN=LECRK57 PE=2
SV=2
Length=659
Score = 231 bits (589), Expect = 4e-63, Method: Composition-based stats.
Identities = 71/281 (25%), Positives = 120/281 (43%), Gaps = 20/281 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG+V Y G+ +AVK D Q S + EI + L H ++++
Sbjct 339 LGKGGFGQV----YKGMLPGSDAEIAVKRTSHD-SRQGMSEFLAEISTIGRLRHPNLVRL 393
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-------HSIGLAQLLLFAQQICEGMAYLH 1015
G C + +++L LV +++P GSL L R + Q + + + +LH
Sbjct 394 LGYC--KHKENLYLVYDFMPNGSLDRCLTRSNTNENQERLTWEQRFKIIKDVATALLHLH 451
Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+ +HRD+ NVLLD+ ++GDFGLAK +G + R G + + APE
Sbjct 452 QEWVQVIVHRDIKPANVLLDHGMNARLGDFGLAKLYDQGFDPQTSRVAG--TLGYIAPEL 509
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
L+ + ++DV++FG+ + E++ + L+ +L + E
Sbjct 510 LRTGRATTSTDVYAFGLVMLEVVCGRRLIERRAAENEAVLVDWILELWESGKLFDAAEES 569
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
R + V L C RP ++ IL V
Sbjct 570 IRQEQNRGEIELVLKLGLLCAHHTELIRPNMSAVLQILNGV 610
Score = 205 bits (521), Expect = 3e-54, Method: Composition-based stats.
Identities = 49/261 (19%), Positives = 92/261 (35%), Gaps = 40/261 (15%)
Query 579 LSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S+ + K + LG+G VY+G L G +
Sbjct 321 FSYKELFNATKGFKEKQLLGKGGFGQVYKGML------------------------PGSD 356
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+ +K F S + ++ H +L + G C +V +++ +G LD
Sbjct 357 AEIAVKRTSHDSRQGMSEFLAEISTIGRLRHPNLVRLLGYCKHKENLYLVYDFMPNGSLD 416
Query 697 VWLRR-----ERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLAR-LGL 747
L R + + + + + +A+AL +L + +VH ++ N+LL +
Sbjct 417 RCLTRSNTNENQERLTWEQRFKIIKDVATALLHLHQEWVQVIVHRDIKPANVLLDHGMNA 476
Query 748 AEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
G KL D G + ++APE L G +T+ D + FG +LE+
Sbjct 477 RLGDFGLAKLYDQGF---DPQTSRVAGTLGYIAPELLRTGRA--TTSTDVYAFGLVMLEV 531
Query 808 CFDGEAPLQSRSPSEKEHFYQ 828
+ + +E
Sbjct 532 VCGRRLIERRAAENEAVLVDW 552
>sp|Q9FLJ8|Y5613_ARATH Probable receptor-like protein kinase At5g61350
OS=Arabidopsis thaliana OX=3702 GN=At5g61350 PE=2 SV=1
Length=842
Score = 235 bits (599), Expect = 4e-63, Method: Composition-based stats.
Identities = 82/396 (21%), Positives = 140/396 (35%), Gaps = 38/396 (10%)
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859
G +L + + + S F L +++ +
Sbjct 439 LGVVVLLVRWQRRPKDWQKQNS----FSSWLLPLHASHSSYISS-------KGGSTSRRM 487
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919
++ + + + G G FGKV + D
Sbjct 488 SIFGSKKSKSNGFSSFFSNQGLGRYFPFTELQTATQNFDENAVCGVGGFGKVYIGEIDG- 546
Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979
G VA+K + Q + ++ EI +L L H H++ G C++ E + LV E
Sbjct 547 ----GTQVAIKR-GSQSSEQGINEFQTEIQMLSKLRHRHLVSLIGFCDENKE--MILVYE 599
Query 980 YVPLGSLRDYLPRHS---------IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAAR 1027
Y+ G LRD+L + Q L G+ YLH Q IHRD+
Sbjct 600 YMSNGPLRDHLYGSKENDPNPIPTLSWKQRLEICIGSARGLHYLHTGAAQGIIHRDVKTT 659
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
N+LLD + + K+ DFGL+K P + V + PE + + SDV+SF
Sbjct 660 NILLDENLVAKVSDFGLSKDAPMDEGH--VSTAVKGSFGYLDPEYFRRQQLTDKSDVYSF 717
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR---LTELLERGERLPRPDKCPCEV 1144
GV L+E+L C P E + +A+ M + R L ++++ +
Sbjct 718 GVVLFEVL--CARPVINPQLPREQVNLAEYAMNLHRKGMLEKIIDPKIVGTISKGSLRKF 775
Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180
+ C RP +++ L+ + + A
Sbjct 776 VEAAEKCLAEYGVDRPGMGDVLWNLEYALQLQEASA 811
Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats.
Identities = 56/292 (19%), Positives = 98/292 (34%), Gaps = 54/292 (18%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
+ + + + + G G VY G +
Sbjct 512 YFPFTELQTATQNFDENAVCGVGGFGKVYIGEIDGG------------------------ 547
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+V +K S F ++S++ H HL + G C E I+V EY+ +GPL
Sbjct 548 -TQVAIKRGSQSSEQGINEFQTEIQMLSKLRHRHLVSLIGFCDENKEMILVYEYMSNGPL 606
Query 696 DVWLRRERGH-------VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARL 745
L + + + ++ + A L YL + ++H +V NILL
Sbjct 607 RDHLYGSKENDPNPIPTLSWKQRLEICIGSARGLHYLHTGAAQGIIHRDVKTTNILLDE- 665
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGF 800
+ K+SD G+ A E V +L PE L+ D + F
Sbjct 666 ------NLVAKVSDFGLSKDAPMDEGHVSTAVKGSFGYLDPEYFR--RQQLTDKSDVYSF 717
Query 801 GATLLEICFDG-----EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ 847
G L E+ + P + + +E R+ L + P++ S+
Sbjct 718 GVVLFEVLCARPVINPQLPREQVNLAEYAMNLHRKGMLEKIIDPKIVGTISK 769
>sp|O08679|MARK2_RAT Serine/threonine-protein kinase MARK2 OS=Rattus
norvegicus OX=10116 GN=Mark2 PE=1 SV=1
Length=722
Score = 233 bits (593), Expect = 4e-63, Method: Composition-based stats.
Identities = 84/326 (26%), Positives = 129/326 (40%), Gaps = 29/326 (9%)
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
S T PT + + +S S H + ++ +G
Sbjct 1 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMLRGRNSATSADEQPHIGNYRLLKTIG 60
Query 905 EGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963
+G+F KV L + TG+ VAVK + K +E+ I++ L H +I+K
Sbjct 61 KGNFAKVKL----ARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLF 116
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHR 1022
E EK+L LVMEY G + DYL H + + +QI + Y H + +HR
Sbjct 117 EVIE--TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHR 174
Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YA 1081
DL A N+LLD D +KI DFG + G++ + + APE + K+
Sbjct 175 DLKAENLLLDADMNIKIADFGFSNEFTFGNKL----DTFCGSPPYAAPELFQGKKYDGPE 230
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
DVWS GV LY L++ + L E + RG + P
Sbjct 231 VDVWSLGVILYTLVSGSLPFD---------------GQNLKELRERVLRG-KYRIPFYMS 274
Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167
+ +L+K S R T E ++
Sbjct 275 TDCENLLKKFLILNPSKRGTLEQIMK 300
Score = 193 bits (490), Expect = 7e-50, Method: Composition-based stats.
Identities = 60/355 (17%), Positives = 113/355 (32%), Gaps = 49/355 (14%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
+P SN++ R + S + + L +G+G V R + G
Sbjct 27 KPSSKSNMLRGRNSATS---------ADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGK 77
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLA 671
V +K++D + + + + +M ++H ++
Sbjct 78 ------------------------EVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIV 113
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
+ V +V EY G + +L G + +Q+ SA+ Y K +V
Sbjct 114 KLFEVIETEKTLYLVMEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYCHQKFIV 172
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGA 788
H ++ N+LL IK++D G + P+ APE G
Sbjct 173 HRDLKAENLLLD-------ADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKK 225
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQ 847
+D W G L + G P ++ E R +R+P L +
Sbjct 226 YD-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 283
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902
L P++R + I++D H ++ P + +
Sbjct 284 FLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYT 338
>sp|Q9LK03|PERK2_ARATH Proline-rich receptor-like protein kinase
PERK2 OS=Arabidopsis thaliana OX=3702 GN=PERK2 PE=2 SV=3
Length=717
Score = 232 bits (592), Expect = 4e-63, Method: Composition-based stats.
Identities = 72/279 (26%), Positives = 120/279 (43%), Gaps = 21/279 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V G+ VAVK LK + Q ++ E+ I+ ++H H++
Sbjct 360 LGQGGFGYVFKGMLR-----NGKEVAVKQLK-EGSSQGEREFQAEVGIISRVHHRHLVAL 413
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017
G C ++ LV E+VP +L +L R ++ + L A +G++YLH
Sbjct 414 VGYCIADAQR--LLVYEFVPNNTLEFHLHGKGRPTMEWSSRLKIAVGSAKGLSYLHENCN 471
Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ A N+L+D K+ DFGLAK + + + R + APE
Sbjct 472 PKIIHRDIKASNILIDFKFEAKVADFGLAKIASDTNTHVSTR--VMGTFGYLAPEYASSG 529
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMT----VLRLTELLERG 1131
K SDV+SFGV L EL+T + L+ A+ + + ++++
Sbjct 530 KLTEKSDVFSFGVVLLELITGRRPIDVNNVHADNSLVDWARPLLNQVSELGNFEVVVDKK 589
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ + C + A RP + + +L+
Sbjct 590 LNNEYDKEEMARMVACAAACVRSTAPRRPRMDQVARVLE 628
Score = 227 bits (578), Expect = 3e-61, Method: Composition-based stats.
Identities = 64/293 (22%), Positives = 106/293 (36%), Gaps = 52/293 (18%)
Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
P PG L I +G T N +LS ++ + LGQG V++G LR
Sbjct 326 PPSPGLALGLGIYQG------TFNYEELS---RATNGFSEANLLGQGGFGYVFKGMLRNG 376
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
V +K L F ++S+V H HL
Sbjct 377 K-------------------------EVAVKQLKEGSSQGEREFQAEVGIISRVHHRHLV 411
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLENK-- 728
+ G C+ + ++V E+V + L+ L + R + + ++ +A A LSYL
Sbjct 412 ALVGYCIADAQRLLVYEFVPNNTLEFHLHGKGRPTMEWSSRLKIAVGSAKGLSYLHENCN 471
Query 729 -NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPE 782
++H ++ NIL+ A K++D G+ A V +LAPE
Sbjct 472 PKIIHRDIKASNILIDFKFEA-------KVADFGLAKIASDTNTHVSTRVMGTFGYLAPE 524
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
G L+ D + FG LLE+ + ++ + L +
Sbjct 525 YASSG--KLTEKSDVFSFGVVLLELITGRRPIDVNNVHADNSLVDWARPLLNQ 575
>sp|Q10925|SID3_CAEEL Tyrosine-protein kinase sid-3 OS=Caenorhabditis
elegans OX=6239 GN=sid-3 PE=1 SV=2
Length=1237
Score = 239 bits (609), Expect = 4e-63, Method: Composition-based stats.
Identities = 88/315 (28%), Positives = 142/315 (45%), Gaps = 24/315 (8%)
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918
+ + + + + ++ + + + +K +GEG F V +
Sbjct 69 MSREMWNRSDPKQVYIQADQSMPAQNSIDEKALIPNEQIKLYELIGEGSFAVVKRGTWTQ 128
Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978
+N GT VAVK L+ D P + E L L H +I+ G +V
Sbjct 129 SN-GTHVNVAVKILR-DISPNIMDDLRVEASHLLKLQHPSLIRLYGIVRQPA----MMVF 182
Query 979 EYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND- 1034
E GSL D L + +++L + QI + + +L ++H +HRD+AARN+LL D
Sbjct 183 ELCEGGSLLDRLRDDKKAILLVSRLHDYCMQIAKALQFLESKHCVHRDVAARNILLARDE 242
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
R VKI DFGL +A+ E + Y + P W PE L+ KF +ASDVWS+GVT++E+
Sbjct 243 RTVKICDFGLMRALKENEQMYTMAPQKKVPFAWCPPEALRHRKFSHASDVWSYGVTIWEV 302
Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154
T + + + + ++ GERL +P C +Y +MKNCW+
Sbjct 303 FTFGEE--------------PWVGCRAIDVLKNIDAGERLEKPKYCSERIYQIMKNCWKF 348
Query 1155 EASFRPTFENLIPIL 1169
+ R F + L
Sbjct 349 NPAERCKFGAIREDL 363
Score = 223 bits (567), Expect = 5e-58, Method: Composition-based stats.
Identities = 66/290 (23%), Positives = 110/290 (38%), Gaps = 41/290 (14%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ ++I +G+G+ V G + G + V +K+
Sbjct 102 IPNEQIKLYELIGEGSFAVVKRGTW---------------------TQSNGTHVNVAVKI 140
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
L +I AS + ++ H L ++G+ + +MV E E G L LR ++
Sbjct 141 LRDISPNIMDDLRVEASHLLKLQHPSLIRLYGIVRQ--PAMMVFELCEGGSLLDRLRDDK 198
Query 704 GHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ + ++ Q+A AL +LE+K+ VH +V RNILLAR +K+ D G+
Sbjct 199 KAILLVSRLHDYCMQIAKALQFLESKHCVHRDVAARNILLAR------DERTVKICDFGL 252
Query 763 GLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
E+ W PE L S A D W +G T+ E+ GE P
Sbjct 253 MRALKENEQMYTMAPQKKVPFAWCPPEALRH--RKFSHASDVWSYGVTIWEVFTFGEEPW 310
Query 816 QSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
+ RL P+ ++ + C + P +R F I
Sbjct 311 VGCRAIDVLKNIDAGERLEKPKYCSERIYQIMKNCWKFNPAERCKFGAIR 360
>sp|A0A8I5ZNK2|OXSR1_RAT Serine/threonine-protein kinase OSR1
OS=Rattus norvegicus OX=10116 GN=Oxsr1 PE=1 SV=1
Length=528
Score = 228 bits (580), Expect = 4e-63, Method: Composition-based stats.
Identities = 71/293 (24%), Positives = 122/293 (42%), Gaps = 30/293 (10%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
P ++ + +G G V P E VA+K + + +EI
Sbjct 9 PWSINRDDYELQEVIGSGATAVVQAAYCAPKK----ERVAIKRINLEKCQTSMDELLKEI 64
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQ 999
+ +H +I+ Y + E L LVM+ + GS+ D + + +
Sbjct 65 QAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGGSVLDIIKHIVAKGEHKGGVLDEST 122
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--V 1057
+ +++ EG+ YLH IHRD+ A N+LL D V+I DFG++ + G + R V
Sbjct 123 IATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKV 182
Query 1058 REDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQS-PPTK--FLELIG 1113
R+ W APE +++ + + +D+WSFG+T EL T PP K L L
Sbjct 183 RKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQN 242
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
T ++ E+L++ + ++ C + + RPT L+
Sbjct 243 DPPSLDTGVQDKEMLKKYGK---------SFRKMISLCLQKDPEKRPTAAELL 286
Score = 177 bits (449), Expect = 7e-46, Method: Composition-based stats.
Identities = 53/315 (17%), Positives = 103/315 (33%), Gaps = 61/315 (19%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+++ + +G G V P ++R V +
Sbjct 10 WSINRDDYELQEVIGSGATAVV-------------------QAAYCAPKKER-----VAI 45
Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K ++ ++ + MSQ H ++ + V E +V + + G + ++
Sbjct 46 KRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIK 105
Query 701 R-------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
+ G + + + +++ L YL +H +V NILL G
Sbjct 106 HIVAKGEHKGGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG------- 158
Query 754 FIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
++++D GV + R+ V W+APE + D W FG T
Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKADIWSFGITA 217
Query 805 LEICFDGEAPLQSRSPSEKEHFY-----------QRQHRLPEPSCPQLATLTSQCLTYEP 853
+E+ G AP P + + + + + S CL +P
Sbjct 218 IELA-TGAAPYHKYPPMKVLMLTLQNDPPSLDTGVQDKEMLKKYGKSFRKMISLCLQKDP 276
Query 854 TQRPSFRTILRDLTR 868
+RP+ +LR
Sbjct 277 EKRPTAAELLRHKFF 291
>sp|Q9FIZ3|GSO2_ARATH LRR receptor-like serine/threonine-protein
kinase GSO2 OS=Arabidopsis thaliana OX=3702 GN=GSO2 PE=1
SV=2
Length=1252
Score = 239 bits (609), Expect = 5e-63, Method: Composition-based stats.
Identities = 71/300 (24%), Positives = 125/300 (42%), Gaps = 22/300 (7%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
D + YL + +G G GKV GE +AVK + + +
Sbjct 938 WDDIMEATHYLNEEFMIGSGGSGKVYKAELK-----NGETIAVKKILWKDDLMSNKSFNR 992
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSIGLAQ 999
E+ L T+ H H++K G C + + L+ EY+ GS+ D+L + +G
Sbjct 993 EVKTLGTIRHRHLVKLMGYCSSKADGLNLLIYEYMANGSVWDWLHANENTKKKEVLGWET 1052
Query 1000 LLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
L A + +G+ YLH +HRD+ + NVLLD++ +GDFGLAK + ++
Sbjct 1053 RLKIALGLAQGVEYLHYDCVPPIVHRDIKSSNVLLDSNIEAHLGDFGLAKILTGNYDTNT 1112
Query 1057 -VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
+ APE K SDV+S G+ L E++T +++ + +++
Sbjct 1113 ESNTMFAGSYGYIAPEYAYSLKATEKSDVYSMGIVLMEIVTGKMPTEAMFDEETDMVRWV 1172
Query 1116 QGQMTVLRLTELLER------GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ + +E E+ LP ++ +V + C ++ RP+ L
Sbjct 1173 ETVLDTPPGSEAREKLIDSELKSLLPCEEEAAYQVLEIALQCTKSYPQERPSSRQASEYL 1232
Score = 176 bits (446), Expect = 2e-43, Method: Composition-based stats.
Identities = 47/272 (17%), Positives = 94/272 (35%), Gaps = 54/272 (20%)
Query 577 SQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
S + + + + + +G G VY+ L+ G
Sbjct 934 SDIKWDDIMEATHYLNEEFMIGSGGSGKVYKAELK-----------------------NG 970
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEH 692
+ + V K+L +F + + H HL + G C + N+++ EY+ +
Sbjct 971 ETIAVK-KILWKDDLMSNKSFNREVKTLGTIRHRHLVKLMGYCSSKADGLNLLIYEYMAN 1029
Query 693 GPLDVWLR-----RERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744
G + WL +++ + ++ +A LA + YL +VH ++ N+LL
Sbjct 1030 GSVWDWLHANENTKKKEVLGWETRLKIALGLAQGVEYLHYDCVPPIVHRDIKSSNVLLD- 1088
Query 745 LGLAEGTSPFIKLSDPGVGL--------GALSREERVERIPWLAPECLPGGANSLSTAMD 796
++ L D G+ S ++APE + + D
Sbjct 1089 ------SNIEAHLGDFGLAKILTGNYDTNTESNTMFAGSYGYIAPEYA--YSLKATEKSD 1140
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
+ G L+EI G+ P ++ E +
Sbjct 1141 VYSMGIVLMEIV-TGKMPTEAMFDEETDMVRW 1171
>sp|Q9XID3|Y1343_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At1g34300 OS=Arabidopsis thaliana OX=3702
GN=At1g34300 PE=1 SV=1
Length=829
Score = 234 bits (598), Expect = 5e-63, Method: Composition-based stats.
Identities = 69/356 (19%), Positives = 126/356 (35%), Gaps = 40/356 (11%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
L C P + + + + L
Sbjct 443 LWWCCCRKNPRFGTLSS------------HYTLLEYASGAPVQFTYKELQRCTKSFKEKL 490
Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963
G G FG V +VAVK L + Q ++ E+ + + +H ++++
Sbjct 491 GAGGFGTVYRGVLTNR-----TVVAVKQL--EGIEQGEKQFRMEVATISSTHHLNLVRLI 543
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018
G C + LV E++ GSL ++L + A +G+ YLH +
Sbjct 544 GFCSQGRHR--LLVYEFMRNGSLDNFLFTTDSAKFLTWEYRFNIALGTAKGITYLHEECR 601
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+H D+ N+L+D++ K+ DFGLAK + Y + + APE L
Sbjct 602 DCIVHCDIKPENILVDDNFAAKVSDFGLAKLLNPKDNRYNM-SSVRGTRGYLAPEWLANL 660
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
SDV+S+G+ L EL++ + S T + A + +L+
Sbjct 661 PITSKSDVYSYGMVLLELVSGKRNFDVSEKTNHKKFSIWAYEEFEKGNTKAILDTRL--- 717
Query 1136 RPDKCPCEVYHLMKN------CWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
+ ++ +M+ C + + RPT ++ +L+ + E P S
Sbjct 718 -SEDQTVDMEQVMRMVKTSFWCIQEQPLQRPTMGKVVQMLEGITEIKNPLCPKTIS 772
Score = 205 bits (521), Expect = 3e-53, Method: Composition-based stats.
Identities = 63/353 (18%), Positives = 121/353 (34%), Gaps = 73/353 (21%)
Query 550 CCLPQPG---ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606
CC P +S+ ++ A +P Q ++ + + + LG G VY G
Sbjct 447 CCRKNPRFGTLSSHYTLLEYASGAPV-----QFTYKELQRCTKSFKEKLGAGGFGTVYRG 501
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS 666
L V +K L F + +S
Sbjct 502 VL-------------------------TNRTVVAVKQL-EGIEQGEKQFRMEVATISSTH 535
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--RERGHVPMAWKMVVAQQLASALSY 724
H +L + G C +G ++V E++ +G LD +L + ++ +A A ++Y
Sbjct 536 HLNLVRLIGFCSQGRHRLLVYEFMRNGSLDNFLFTTDSAKFLTWEYRFNIALGTAKGITY 595
Query 725 LEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVER 775
L +VH ++ NIL+ + K+SD G+ +
Sbjct 596 LHEECRDCIVHCDIKPENILVD-------DNFAAKVSDFGLAKLLNPKDNRYNMSSVRGT 648
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE-APLQSRSPSEKEHFYQRQH--- 831
+LAPE L +++ D + +G LLE+ + ++ +K + +
Sbjct 649 RGYLAPEWLAN--LPITSKSDVYSYGMVLLELVSGKRNFDVSEKTNHKKFSIWAYEEFEK 706
Query 832 ---------RLPEPSCPQLATLTSQ------CLTYEPTQRPSFRTILRDLTRL 869
RL E + + C+ +P QRP+ +++ L +
Sbjct 707 GNTKAILDTRLSEDQTVDMEQVMRMVKTSFWCIQEQPLQRPTMGKVVQMLEGI 759
>sp|Q5XF57|Y5576_ARATH Probable receptor-like serine/threonine-protein
kinase At5g57670 OS=Arabidopsis thaliana OX=3702 GN=At5g57670
PE=2 SV=1
Length=579
Score = 229 bits (583), Expect = 5e-63, Method: Composition-based stats.
Identities = 68/306 (22%), Positives = 121/306 (40%), Gaps = 19/306 (6%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935
+ + +G G + +V + G +AVK L +
Sbjct 246 PKPQPLIQCFTYNEISKATNDFHQGNIVGIGGYSEVYRG-----DLWDGRRIAVKRLAKE 300
Query 936 CGPQHRS-GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993
G ++ + E+ I+ + H + GCC ++G L LV + G+L L +
Sbjct 301 SGDMNKEKEFLTELGIISHVSHPNTALLLGCCVEKG---LYLVFRFSENGTLYSALHENE 357
Query 994 --SIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
S+ A + G+ YLH IHRD+ + NVLL D +I DFGLAK +
Sbjct 358 NGSLDWPVRYKIAVGVARGLHYLHKRCNHRIIHRDIKSSNVLLGPDYEPQITDFGLAKWL 417
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
P ++ V + + APE L + +D+++FG+ L E++T
Sbjct 418 PNKWTHHAV-IPVEGTFGYLAPESLMQGTIDEKTDIYAFGILLLEIITGRRPVNPTQKHI 476
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
L A+ M +EL++ + D+ ++ +C + RPT ++ +
Sbjct 477 LL---WAKPAMETGNTSELVDPKLQDKYDDQQMNKLVLTASHCVQQSPILRPTMTQVLEL 533
Query 1169 LKTVHE 1174
L +E
Sbjct 534 LTNGNE 539
Score = 182 bits (461), Expect = 4e-47, Method: Composition-based stats.
Identities = 70/366 (19%), Positives = 121/366 (33%), Gaps = 63/366 (17%)
Query 566 GARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
+ P+ L + +++ + + Q + +G G + VY G L
Sbjct 243 KNKPKPQPL-IQCFTYNEISKATNDFHQGNIVGIGGYSEVYRGDLWDGR----------- 290
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDI--ALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
R+ +K L D+ F ++S VSH + A + G CV
Sbjct 291 --------------RIAVKRLAKESGDMNKEKEFLTELGIISHVSHPNTALLLGCCVEKG 336
Query 682 ENIMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCG 737
+V + E+G L L E G + + +A +A L YL N ++H ++
Sbjct 337 -LYLVFRFSENGTLYSALHENENGSLDWPVRYKIAVGVARGLHYLHKRCNHRIIHRDIKS 395
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV------ERIPWLAPECLPGGANSL 791
N+LL G +++D G+ ++ +LAPE L G ++
Sbjct 396 SNVLL-------GPDYEPQITDFGLAKWLPNKWTHHAVIPVEGTFGYLAPESLMQG--TI 446
Query 792 STAMDKWGFGATLLEICFDGEA-------------PLQSRSPSEKEHFYQRQHRLPEPSC 838
D + FG LLEI P + + + Q + +
Sbjct 447 DEKTDIYAFGILLLEIITGRRPVNPTQKHILLWAKPAMETGNTSELVDPKLQDKYDDQQM 506
Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898
+L S C+ P RP+ +L LT +A + D D
Sbjct 507 NKLVLTASHCVQQSPILRPTMTQVLELLTNGNEAEIAKSWRMPKDMTNDDDDNNEWDDYS 566
Query 899 KIRDLG 904
I
Sbjct 567 MIFGYD 572
>sp|P50527|STE20_SCHPO Serine/threonine-protein kinase shk1/pak1
OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812
GN=shk1 PE=1 SV=2
Length=658
Score = 231 bits (588), Expect = 5e-63, Method: Composition-based stats.
Identities = 61/277 (22%), Positives = 115/277 (42%), Gaps = 25/277 (9%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+ +G+G G V Y GT VA+K + + P+ + EI ++++ +H
Sbjct 386 YRNFVKIGQGASGDV----YSARQVGTNLSVAIKKMNINQQPK-KEFIVNEILVMKSHHH 440
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016
++I+ + + E L +VMEY+ GSL + + +++ Q+ ++ EG+ +LH
Sbjct 441 KNIVNFIDTFFYKSE--LWMVMEYMRGGSLTEVVTNNTLSEGQIAAICKETLEGLQHLHE 498
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRD+ + N+LL +K+ DFG + R +W APE +
Sbjct 499 NGIVHRDIKSDNILLSLQGDIKLTDFGFCAQIDSNM---TKRTTMVGTPYWMAPEVVTRK 555
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
++ + DVWS G+ E++ PP + T+ ++ R
Sbjct 556 EYGFKVDVWSLGIMAIEMV-----EGEPPYLNENPLRALYLIATIGT--------PKISR 602
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKT 1171
P+ + + RP+ L+ P LK
Sbjct 603 PELLSSVFHDFLSKSLTVNPKQRPSSGELLRHPFLKQ 639
Score = 189 bits (480), Expect = 5e-49, Method: Composition-based stats.
Identities = 60/282 (21%), Positives = 92/282 (33%), Gaps = 44/282 (16%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
+GQG +VY R G L V +K ++ +
Sbjct 391 KIGQGASGDVYSA------------------------RQVGTNLSVAIKKMNINQQPKKE 426
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
+M H ++ E MV EY+ G L + +
Sbjct 427 FIVNEILVMKSHHHKNIVNFIDTFFYKSELWMVMEYMRGGSLTEVVTNN--TLSEGQIAA 484
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----R 769
+ ++ L +L +VH ++ NILL+ G IKL+D G S R
Sbjct 485 ICKETLEGLQHLHENGIVHRDIKSDNILLSLQGD-------IKLTDFGFCAQIDSNMTKR 537
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
V W+APE + +D W G +E+ +GE P + +P +
Sbjct 538 TTMVGTPYWMAPEVVTRKEYGF--KVDVWSLGIMAIEMV-EGEPPYLNENPLRALYLIAT 594
Query 830 QHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
PE S+ LT P QRPS +LR
Sbjct 595 IGTPKISRPELLSSVFHDFLSKSLTVNPKQRPSSGELLRHPF 636
>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase
kinase 3 OS=Homo sapiens OX=9606 GN=MAP3K3 PE=1 SV=2
Length=626
Score = 230 bits (586), Expect = 5e-63, Method: Composition-based stats.
Identities = 78/279 (28%), Positives = 131/279 (47%), Gaps = 24/279 (9%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP----QHRSGWKQEID 949
++ + LG+G FG+V L + TG +A K ++ D + S + EI
Sbjct 359 PINWRRGKLLGQGAFGRVYLCY----DVDTGRELASKQVQFDPDSPETSKEVSALECEIQ 414
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQIC 1008
+L+ L HE I++Y GC D+ EK+L + MEY+P GS++D L + + + + +QI
Sbjct 415 LLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQIL 474
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
EGM+YLH+ +HRD+ N+L D+ VK+GDFG +K + +W
Sbjct 475 EGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWM 534
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
+PE + + +DVWS G T+ E+LT + PP E + + ++
Sbjct 535 SPEVISGEGYGRKADVWSLGCTVVEMLT-----EKPPWAEYEAMA---------AIFKIA 580
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ P ++ + EA RP+ E L+
Sbjct 581 TQPTNPQLPSHISEHGRDFLRRIF-VEARQRPSAEELLT 618
Score = 172 bits (436), Expect = 1e-43, Method: Composition-based stats.
Identities = 61/373 (16%), Positives = 115/373 (31%), Gaps = 68/373 (18%)
Query 478 SHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCL 537
++P R ++V + + R+R+ Q F L RS + G
Sbjct 274 TYPRRYHVSVHHKDYSDGRRTFPRIRR----HQGNLFTLVPSSRSLST--------NGEN 321
Query 538 LRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQ 597
+ R + ++ N + ++ ++ + + LGQ
Sbjct 322 MGLAVQYLDPRGRL--RSADSENALSVQERNVPTKSPSAPI---------NWRRGKLLGQ 370
Query 598 GTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE 657
G VY L D G+EL DP + +
Sbjct 371 GAFGRVY----------------------LCYDVDTGRELASKQVQFDPDSPETSKEVSA 408
Query 658 ---TASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
L+ + H + +G E + EY+ G + L+ G + +
Sbjct 409 LECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKA-YGALTESVTR 467
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-------VGLG 765
+Q+ +SYL + +VH ++ G NIL ++ +KL D G + +
Sbjct 468 KYTRQILEGMSYLHSNMIVHRDIKGANIL-------RDSAGNVKLGDFGASKRLQTICMS 520
Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
W++PE + G D W G T++E+ + + P
Sbjct 521 GTGMRSVTGTPYWMSPEVISG--EGYGRKADVWSLGCTVVEMLTE-KPPWAEYEAMAAIF 577
Query 826 FYQRQHRLPEPSC 838
Q P+
Sbjct 578 KIATQPTNPQLPS 590
>sp|Q9LK43|TMK4_ARATH Receptor-like kinase TMK4 OS=Arabidopsis
thaliana OX=3702 GN=TMK4 PE=1 SV=1
Length=928
Score = 236 bits (601), Expect = 5e-63, Method: Composition-based stats.
Identities = 82/292 (28%), Positives = 132/292 (45%), Gaps = 26/292 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG G FG V +DGT AVK ++ A G + S ++ EI +L + H H++
Sbjct 584 LGRGGFGVVYAGEL---HDGTKT--AVKRMECAAMGNKGMSEFQAEIAVLTKVRHRHLVA 638
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR------HSIGLAQLLLFAQQICEGMAYLH 1015
G C + E+ LV EY+P G+L +L + Q + A + G+ YLH
Sbjct 639 LLGYCVNGNER--LLVYEYMPQGNLGQHLFEWSELGYSPLTWKQRVSIALDVARGVEYLH 696
Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+ Q +IHRDL N+LL +D K+ DFGL K P+G Y V + APE
Sbjct 697 SLAQQSFIHRDLKPSNILLGDDMRAKVADFGLVKNAPDGK--YSVETRLAGTFGYLAPEY 754
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTELLER 1130
+ DV++FGV L E+LT + S P + L+ + + + + L++
Sbjct 755 AATGRVTTKVDVYAFGVVLMEILTGRKALDDSLPDERSHLVTWFRRILINKENIPKALDQ 814
Query 1131 GERLPRPDKCPCEVYHLMKN---CWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L ++ +Y + + C E RP + + +L + EK++
Sbjct 815 --TLEADEETMESIYRVAELAGHCTAREPQQRPDMGHAVNVLGPLVEKWKPS 864
Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats.
Identities = 76/348 (22%), Positives = 129/348 (37%), Gaps = 75/348 (22%)
Query 546 SLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605
+ P G+ S+ ++ G + L Q+ ++ + LG+G VY
Sbjct 541 NFNALNSPSSGDNSDRFLLEGGSVTIPMEVLRQV------TNNFSEDNILGRGGFGVVYA 594
Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMS 663
G L + +K ++ + + F ++++
Sbjct 595 GELHDG-------------------------TKTAVKRMECAAMGNKGMSEFQAEIAVLT 629
Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--RERGHVPMAW--KMVVAQQLA 719
+V H HL + G CV G E ++V EY+ G L L E G+ P+ W ++ +A +A
Sbjct 630 KVRHRHLVALLGYCVNGNERLLVYEYMPQGNLGQHLFEWSELGYSPLTWKQRVSIALDVA 689
Query 720 SALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV--- 773
+ YL + ++ +H ++ NILL G K++D G+ A + V
Sbjct 690 RGVEYLHSLAQQSFIHRDLKPSNILL-------GDDMRAKVADFGLVKNAPDGKYSVETR 742
Query 774 --ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
+LAPE G ++T +D + FG L+EI G L P E+ H
Sbjct 743 LAGTFGYLAPEYAATG--RVTTKVDVYAFGVVLMEIL-TGRKALDDSLPDERSHLVTWFR 799
Query 832 RL--------------------PEPSCPQLATLTSQCLTYEPTQRPSF 859
R+ S ++A L C EP QRP
Sbjct 800 RILINKENIPKALDQTLEADEETMESIYRVAELAGHCTAREPQQRPDM 847
>sp|Q9C9L5|WAKLH_ARATH Wall-associated receptor kinase-like 9
OS=Arabidopsis thaliana OX=3702 GN=WAKL9 PE=2 SV=1
Length=792
Score = 234 bits (596), Expect = 5e-63, Method: Composition-based stats.
Identities = 71/280 (25%), Positives = 114/280 (41%), Gaps = 19/280 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G G V G +VAVK K + E+ IL + H +I+K
Sbjct 453 LGQGGQGTVYKGML-----VDGRIVAVKKSKV-VDEDKLEEFINEVVILSQINHRNIVKL 506
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHAQ 1017
GCC + K LV E++P G+L ++L L A I ++YLH+
Sbjct 507 LGCCLET--KVPVLVYEFIPNGNLFEHLHDEFDENIMATWNIRLRIAIDIAGALSYLHSS 564
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
HRD+ + N++LD K+ DFG ++ V H + + V + PE +
Sbjct 565 ASSPIYHRDVKSTNIMLDEKYRAKVSDFGTSRTVTVDHTH--LTTVVSGTVGYMDPEYFQ 622
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+F SDV+SFGV L EL+T S S + L M +L ++++ R
Sbjct 623 SSQFTDKSDVYSFGVVLVELITGEKSISFLRSQENRTLATYFILAMKENKLFDIIDARIR 682
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ + C + RP+ + L ++
Sbjct 683 DGCMLSQVTATAKVARKCLNLKGRKRPSMREVSMELDSIR 722
Score = 223 bits (567), Expect = 2e-59, Method: Composition-based stats.
Identities = 71/405 (18%), Positives = 131/405 (32%), Gaps = 68/405 (17%)
Query 504 KFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGE---TSN 560
F + + G G SF S+ + + ++ + G
Sbjct 362 HFKCVYNNHRPLAIGLGASFGSLIFVVGIYLLYKFIKKQRKLNQKKKFFKRNGGLLLQQQ 421
Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620
LI G + +L + + LGQG + VY+G L
Sbjct 422 LISTVGMVEKTIVFSSRELEK---ATENFSSNRILGQGGQGTVYKGMLVDGRI------- 471
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680
V +K D F ++SQ++H ++ + G C+
Sbjct 472 ------------------VAVKKSKVVDEDKLEEFINEVVILSQINHRNIVKLLGCCLET 513
Query 681 PENIMVTEYVEHGPLDVWLRRERGH---VPMAWKMVVAQQLASALSYLE---NKNLVHGN 734
++V E++ +G L L E ++ +A +A ALSYL + + H +
Sbjct 514 KVPVLVYEFIPNGNLFEHLHDEFDENIMATWNIRLRIAIDIAGALSYLHSSASSPIYHRD 573
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGAN 789
V NI+L A K+SD G + + ++ PE ++
Sbjct 574 VKSTNIMLDEKYRA-------KVSDFGTSRTVTVDHTHLTTVVSGTVGYMDPEYFQ--SS 624
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRS-------------PSEKEHFYQRQHRLPEP 836
+ D + FG L+E+ ++ RS E + F R+ +
Sbjct 625 QFTDKSDVYSFGVVLVELITGEKSISFLRSQENRTLATYFILAMKENKLFDIIDARIRDG 684
Query 837 SC----PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
A + +CL + +RPS R + +L ++
Sbjct 685 CMLSQVTATAKVARKCLNLKGRKRPSMREVSMELDSIRMPCGDMQ 729
>sp|P43450|CDK2_CARAU Cyclin-dependent kinase 2 OS=Carassius auratus
OX=7957 GN=cdk2 PE=1 SV=1
Length=298
Score = 220 bits (560), Expect = 5e-63, Method: Composition-based stats.
Identities = 67/291 (23%), Positives = 120/291 (41%), Gaps = 28/291 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y N TGE VA+K ++ D + S +EI +L+
Sbjct 1 MESFQKVEKIGEGTYGVV----YKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICE 1009
L H +I+K E L LV E++ L+ ++ + I L + + Q+ +
Sbjct 57 ELNHPNIVKLHDVI--HTENKLYLVFEFLHQ-DLKRFMDSSTVTGISLPLVKSYLFQLLQ 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
G+A+ H+ +HRDL +N+L++ +K+ DFGLA+A R +++ A
Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINAQGEIKLADFGLARAFGVP---VRTYTHEVVTLWYRA 170
Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLTE 1126
PE L K+Y A D+WS G E++T S + + +
Sbjct 171 PEILLGCKYYSTAVDIWSLGCIFAEMITRKALFPGDSEIDQLFRIFRTLGTPDESIWPGV 230
Query 1127 LLERGERLPRPDKCPCEV-----------YHLMKNCWETEASFRPTFENLI 1166
+ P ++ L+ + + R + +N +
Sbjct 231 TSMPDYKPSFPKWARQDLSKVVPPLDEDGRDLLGQMLIYDPNKRISAKNAL 281
Score = 169 bits (427), Expect = 3e-45, Method: Composition-based stats.
Identities = 48/266 (18%), Positives = 95/266 (36%), Gaps = 40/266 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
+ ++ +G+GT VY+ + +V G V LK
Sbjct 1 MESFQKVEKIGEGTYGVVYKAKNKVTGE------------------------TVALKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
LD + SL+ +++H ++ +H V + +V E++ H L ++
Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLHDVIHTENKLYLVFEFL-HQDLKRFMDSST 95
Query 704 -GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ + QL L++ + ++H ++ +N+L+ G IKL+D G+
Sbjct 96 VTGISLPLVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAQGE-------IKLADFGL 148
Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + + APE L G STA+D W G E+
Sbjct 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKY-YSTAVDIWSLGCIFAEMITRKALFPGDS 207
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ E P + ++
Sbjct 208 EIDQLFRIFRTLGTPDESIWPGVTSM 233
>sp|Q9ZNQ8|PERK4_ARATH Proline-rich receptor-like protein kinase
PERK4 OS=Arabidopsis thaliana OX=3702 GN=PERK4 PE=1 SV=1
Length=633
Score = 230 bits (587), Expect = 5e-63, Method: Composition-based stats.
Identities = 79/279 (28%), Positives = 124/279 (44%), Gaps = 22/279 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V +G+ VAVK+LKA G R ++ E+DI+ ++H +++
Sbjct 290 LGQGGFGYVHKGVL-----PSGKEVAVKSLKAGSGQGERE-FQAEVDIISRVHHRYLVSL 343
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLH---A 1016
G C G++ LV E+VP +L +L ++ + + L A +G+AYLH
Sbjct 344 VGYCIADGQR--MLVYEFVPNKTLEYHLHGKNLPVMEFSTRLRIALGAAKGLAYLHEDCH 401
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ + N+LLD + + DFGLAK + + + R + APE
Sbjct 402 PRIIHRDIKSANILLDFNFDAMVADFGLAKLTSDNNTHVSTR--VMGTFGYLAPEYASSG 459
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT-VLRLTELLERGERLP 1135
K SDV+S+GV L EL+T + T L+ A+ M L E +
Sbjct 460 KLTEKSDVFSYGVMLLELITGKRPVDNSITMDDTLVDWARPLMARALEDGNFNELADARL 519
Query 1136 RPDKCPCEVYHLMKNC----WETEASFRPTFENLIPILK 1170
+ P E+ M C RP ++ L+
Sbjct 520 EGNYNPQEMAR-MVTCAAASIRHSGRKRPKMSQIVRALE 557
Score = 211 bits (538), Expect = 1e-56, Method: Composition-based stats.
Identities = 66/378 (17%), Positives = 115/378 (30%), Gaps = 54/378 (14%)
Query 552 LPQPGETSNLII--MRGARASPRT-----LNLSQLSFHRVDQKE--ITQLSHLGQGTRTN 602
+P GE S++ R P N S ++ + T + LGQG
Sbjct 238 MPTSGEDSSMYSGPSRPVLPPPSPALALGFNKSTFTYQELAAATGGFTDANLLGQGGFGY 297
Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662
V++G L V +K L F ++
Sbjct 298 VHKGVLPSGK-------------------------EVAVKSLKAGSGQGEREFQAEVDII 332
Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASA 721
S+V H +L + G C+ + ++V E+V + L+ L + + + ++ +A A
Sbjct 333 SRVHHRYLVSLVGYCIADGQRMLVYEFVPNKTLEYHLHGKNLPVMEFSTRLRIALGAAKG 392
Query 722 LSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV----- 773
L+YL ++H ++ NILL + ++D G+ V
Sbjct 393 LAYLHEDCHPRIIHRDIKSANILLD-------FNFDAMVADFGLAKLTSDNNTHVSTRVM 445
Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833
+LAPE G L+ D + +G LLE+ S + + + R
Sbjct 446 GTFGYLAPEYASSG--KLTEKSDVFSYGVMLLELITGKRPVDNSITMDDTLVDWARPLMA 503
Query 834 PEPSCPQLATLTSQCL--TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV 891
L L Y P + T R + +
Sbjct 504 RALEDGNFNELADARLEGNYNPQEMARMVTCAAASIRHSGRKRPKMSQIVRALEGEVSLD 563
Query 892 FHKRYLKKIRDLGEGHFG 909
+K G G
Sbjct 564 ALNEGVKPGHSNVYGSLG 581
>sp|Q80YP0|CDK3_MOUSE Cyclin-dependent kinase 3 OS=Mus musculus
OX=10090 GN=Cdk3 PE=1 SV=3
Length=304
Score = 220 bits (560), Expect = 5e-63, Method: Composition-based stats.
Identities = 76/292 (26%), Positives = 127/292 (43%), Gaps = 30/292 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y N TG++VA+K ++ D + S +EI +L+
Sbjct 1 MDVFQKVEKIGEGTYGVV----YKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009
L H +IIK EK L +V E++ L+ ++ P + L + + Q+ E
Sbjct 57 ELKHPNIIKLLDVVHR--EKKLYMVFEFLTQ-DLKRHMDSSPTSELPLPVVKSYLAQLLE 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
G+++ H+ IHRDL +N+LLD +K+ DFGLA+A Y +++ A
Sbjct 114 GVSFCHSHRVIHRDLKPQNLLLDGLGAIKLADFGLARAFGVPLRTY---THEVVTLWYRA 170
Query 1070 PECLKEYK-FYYASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIGIAQG------ 1117
PE L K + A D+WS G E++T DS + +G
Sbjct 171 PEILLGSKFYSTAVDIWSIGCIFAEMVTGKALFPGDSEIDQLFRIFRTLGTPSEATWPGV 230
Query 1118 -QMTVLR--LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
QM + + +G P P E L+ + + S R + + +
Sbjct 231 SQMPDYQSSFPKWSRKGLEEIVPSLGP-EGKDLLLRLLQYDPSQRISAKTAL 281
Score = 169 bits (427), Expect = 3e-45, Method: Composition-based stats.
Identities = 52/263 (20%), Positives = 94/263 (36%), Gaps = 40/263 (15%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--VLDP 646
++ +G+GT VY+ R +V G V LK LD
Sbjct 4 FQKVEKIGEGTYGVVYKARNKVTGQ------------------------LVALKKIRLDL 39
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GH 705
+ SL+ ++ H ++ + V R + MV E++ L +
Sbjct 40 EAEGVPSTAVREISLLKELKHPNIIKLLDVVHREKKLYMVFEFLTQ-DLKRHMDSSPTSE 98
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+P+ QL +S+ + ++H ++ +N+LL LG IKL+D G+
Sbjct 99 LPLPVVKSYLAQLLEGVSFCHSHRVIHRDLKPQNLLLDGLGA-------IKLADFGLARA 151
Query 766 ----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ V + + APE L G STA+D W G E+
Sbjct 152 FGVPLRTYTHEVVTLWYRAPEILLGSKF-YSTAVDIWSIGCIFAEMVTGKALFPGDSEID 210
Query 822 EKEHFYQRQHRLPEPSCPQLATL 844
+ ++ E + P ++ +
Sbjct 211 QLFRIFRTLGTPSEATWPGVSQM 233
>sp|P59895|NEK6_RAT Serine/threonine-protein kinase Nek6 OS=Rattus
norvegicus OX=10116 GN=Nek6 PE=1 SV=1
Length=313
Score = 220 bits (561), Expect = 5e-63, Method: Composition-based stats.
Identities = 68/330 (21%), Positives = 127/330 (38%), Gaps = 34/330 (10%)
Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911
+P+ P + L P + D + + +G G F +V
Sbjct 4 QPSHMPHGGSPNHLCHVLGPAHPPDPQRHPNTLSFRC----SLADFQIEKKIGRGQFSEV 59
Query 912 SLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
Y T + VA+K ++ + R +EI +L+ L H +IIKY +
Sbjct 60 ----YKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIED 115
Query 970 GEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDL 1024
E L +V+E G L + + I + + Q+C + ++H++ +HRD+
Sbjct 116 NE--LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDI 173
Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084
NV + +VK+GD GL + ++ +PE + E + + SD+
Sbjct 174 KPANVFITATGIVKLGDLGLGRFFS---SETTAAHSLVGTPYYMSPERIHENGYNFKSDI 230
Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP-DKCPCE 1143
WS G LYE+ +M + L + +E+ + P P + +
Sbjct 231 WSLGCLLYEMAALQSPFYG-------------DKMNLFSLCQKIEQCDYPPLPGEHYSEK 277
Query 1144 VYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ L+ C + + RP E + + K +H
Sbjct 278 LRELVSMCIYPDPNHRPDIEYVHQVAKQMH 307
Score = 169 bits (428), Expect = 3e-45, Method: Composition-based stats.
Identities = 52/332 (16%), Positives = 108/332 (33%), Gaps = 41/332 (12%)
Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
+P G ++L + G P R + +G+G + VY+ ++
Sbjct 8 MPHGGSPNHLCHVLGPAHPPDPQRHPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLD 67
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
+ E R +K L+ Q++H ++
Sbjct 68 RKTVALKKVQIFEMMDAKARQD------CVK---------------EIGLLKQLNHPNII 106
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDV---WLRRERGHVPMAWKMVVAQQLASALSYLENK 728
+ E +V E + G L + ++++ +P QL SA+ ++ ++
Sbjct 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 166
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER----VERIPWLAPECL 784
++H ++ N+ + G+ +KL D G+G S V +++PE +
Sbjct 167 RVMHRDIKPANVFITATGI-------VKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERI 219
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS----EKEHFYQRQHRLPEPSCPQ 840
+ D W G L E+ + +K E +
Sbjct 220 HENGYNF--KSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEK 277
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
L L S C+ +P RP + + ++
Sbjct 278 LRELVSMCIYPDPNHRPDIEYVHQVAKQMHVW 309
>sp|Q9Z1J2|NEK4_MOUSE Serine/threonine-protein kinase Nek4 OS=Mus
musculus OX=10090 GN=Nek4 PE=1 SV=1
Length=792
Score = 233 bits (595), Expect = 6e-63, Method: Composition-based stats.
Identities = 64/279 (23%), Positives = 117/279 (42%), Gaps = 27/279 (10%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDI 950
+ +R +G G +G+V+L + G+ +K L + + R +QE +
Sbjct 1 MPQAAYCYMRVVGRGSYGEVTLV----KHRRDGKQYVIKKLNLRNASSRERRAAEQEAQL 56
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQI 1007
L L H +I+ YK E G+ L +VM + G L L + +Q++ + QI
Sbjct 57 LSQLKHPNIVTYKESWE-GGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPESQVVEWFVQI 115
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH +H +HRDL +NV L ++K+GD G+A+ + + + ++
Sbjct 116 AMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVL---ENHGDMASTLIGTPYY 172
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
+PE + Y SDVW+ G +YE+ T + + L
Sbjct 173 MSPELFSNKPYNYKSDVWALGCCVYEMATLKHAF---------------NAKDMNSLVYR 217
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ G+ P P E+ L++ RP+ +++
Sbjct 218 IIEGKLPPMPKVYSTELAELIRTMLSRRPEERPSVRSIL 256
Score = 172 bits (437), Expect = 5e-43, Method: Composition-based stats.
Identities = 58/288 (20%), Positives = 106/288 (37%), Gaps = 38/288 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ +G+G+ V LV R G++ + L +
Sbjct 8 YMRVVGRGSYGEV----------------------TLVKHRRDGKQYVIKKLNLRNASSR 45
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHV-PM 708
A + A L+SQ+ H ++ G +V + E G L L+ ++G + P
Sbjct 46 ERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPE 105
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ + Q+A AL YL K+++H ++ +N+ L R + IK+ D G+ +
Sbjct 106 SQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNI-------IKVGDLGIARVLEN 158
Query 769 R----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ +++PE + D W G + E+ A S
Sbjct 159 HGDMASTLIGTPYYMSPELFSNKPYNY--KSDVWALGCCVYEMATLKHAFNAKDMNSLVY 216
Query 825 HFYQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
+ + +P+ +LA L L+ P +RPS R+ILR
Sbjct 217 RIIEGKLPPMPKVYSTELAELIRTMLSRRPEERPSVRSILRQPYIKHH 264
>sp|P0DH86|SRK_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase SRK OS=Arabidopsis thaliana OX=3702 GN=SRK
PE=2 SV=1
Length=853
Score = 234 bits (598), Expect = 6e-63, Method: Composition-based stats.
Identities = 72/283 (25%), Positives = 116/283 (41%), Gaps = 26/283 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V G+ +AVK L ++ Q + +K E+ ++ L H ++++
Sbjct 530 LGRGGFGIVYKGRL-----LDGQEIAVKRL-SEMSSQGTNEFKNEVRLIARLQHINLVRL 583
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQICEGMAYLHAQ 1017
CC EK L+ EY+ GSL +L + + I G+ YLH
Sbjct 584 LSCCIYADEK--ILIYEYLENGSLDSHLFETTQSSNKLNWQTRFSIINGIARGLLYLHQD 641
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL A NVLLD + KI DFG+A+ R+ + +PE
Sbjct 642 SRFKIIHRDLKASNVLLDKNMTPKISDFGMARIFERDETEANTRK-VVGTYGYMSPEYAM 700
Query 1075 EYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
E F SDV+SFGV + E+++ + L+G + E+++
Sbjct 701 EGIFSVKSDVFSFGVLVLEIVSGKRNRGFHNSGQDNNLLGYTWENWKEGKGLEIVDSIIV 760
Query 1134 -------LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
L +P + + C + A RP +++ +L
Sbjct 761 DSSSSMSLFQPHEVL-RCIQIGLLCVQERAEDRPKMSSVVLML 802
Score = 218 bits (555), Expect = 2e-57, Method: Composition-based stats.
Identities = 49/262 (19%), Positives = 88/262 (34%), Gaps = 46/262 (18%)
Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
+ + + + LG+G VY+GRL
Sbjct 514 FETVVMATENFSDSNILGRGGFGIVYKGRLLDGQ-------------------------E 548
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+ +K L F L++++ H +L + C+ E I++ EY+E+G LD
Sbjct 549 IAVKRLSEMSSQGTNEFKNEVRLIARLQHINLVRLLSCCIYADEKILIYEYLENGSLDSH 608
Query 699 LR---RERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752
L + + + + +A L YL ++H ++ N+LL + +
Sbjct 609 LFETTQSSNKLNWQTRFSIINGIARGLLYLHQDSRFKIIHRDLKASNVLLDK-------N 661
Query 753 PFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
K+SD G+ E V +++PE G S D + FG +LE
Sbjct 662 MTPKISDFGMARIFERDETEANTRKVVGTYGYMSPEYAMEGI--FSVKSDVFSFGVLVLE 719
Query 807 ICFDGEAPLQSRSPSEKEHFYQ 828
I S +
Sbjct 720 IVSGKRNRGFHNSGQDNNLLGY 741
>sp|A7MBB4|M3K13_BOVIN Mitogen-activated protein kinase kinase
kinase 13 OS=Bos taurus OX=9913 GN=MAP3K13 PE=2 SV=1
Length=966
Score = 236 bits (602), Expect = 6e-63, Method: Composition-based stats.
Identities = 83/301 (28%), Positives = 122/301 (41%), Gaps = 35/301 (12%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ + + + D + +++ LG G G V L + E VA+K
Sbjct 142 WNIIGKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRA------EEVAIK 195
Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
++ I LR L H +II +KG C ++MEY G L + L
Sbjct 196 KVREQNETD--------IKHLRKLKHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVL 245
Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
I L+ ++ I GM YLH IHRDL + NVL+ + VKI DFG +K +
Sbjct 246 RAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELS 305
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
+ + V W APE ++ D+WSFGV L+ELLT P K +
Sbjct 306 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG-----EIPYKDV 356
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ I G + LP P CP LMK W+++ RP+F + L
Sbjct 357 DSSAIIWGVGSN---------SLHLPVPSTCPDGFKILMKQTWQSKTRNRPSFRQTLMHL 407
Query 1170 K 1170
Sbjct 408 D 408
Score = 211 bits (537), Expect = 9e-55, Method: Composition-based stats.
Identities = 64/305 (21%), Positives = 108/305 (35%), Gaps = 50/305 (16%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+A L Q V +EI++L LG G + V+ G+ R E
Sbjct 146 GKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAE--------------- 190
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
V +K + + + ++ H ++ GVC + P ++
Sbjct 191 -----------EVAIKKVREQNE-------TDIKHLRKLKHPNIIAFKGVCTQAPCYCII 232
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
EY HG L LR R + + + +AS ++YL ++H ++ N+L+
Sbjct 233 MEYCAHGQLYEVLRAGR-KITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTD 291
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+K+SD G + ++ + W+APE + +S +D W FG
Sbjct 292 A-------VKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 342
Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
L E+ GE P + S +P L Q + RPSFR
Sbjct 343 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKTRNRPSFR 401
Query 861 TILRD 865
L
Sbjct 402 QTLMH 406
>sp|Q99N57|RAF1_MOUSE RAF proto-oncogene serine/threonine-protein
kinase OS=Mus musculus OX=10090 GN=Raf1 PE=1 SV=2
Length=648
Score = 230 bits (587), Expect = 6e-63, Method: Composition-based stats.
Identities = 80/333 (24%), Positives = 135/333 (41%), Gaps = 35/333 (11%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
+ T P+ R + + +S + +G G F
Sbjct 305 WSQPKTPVPAQRERAPGSGT----QEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF 360
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
G V + VAVK LK D P+ ++ E+ +LR H +I+ + G
Sbjct 361 GTVYKGKWHG-------DVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILLFMGYM- 412
Query 968 DQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
+ +L +V ++ SL +L + QL+ A+Q +GM YLHA++ IHRD+
Sbjct 413 --TKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMK 470
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYAS 1082
+ N+ L VKIGDFGLA +V E V W APE ++ + F + S
Sbjct 471 SNNIFLHEGLTVKIGDFGLATVKSRWSGSQQV-EQPTGSVLWMAPEVIRMQDDNPFSFQS 529
Query 1083 DVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
DV+S+G+ LYEL+ + + ++G + RL + C
Sbjct 530 DVYSYGIVLYELMAGELPYAHINNRDQIIFMVGRGYASPDLSRLYK------------NC 577
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
P + L+ +C + RP F ++ ++ +
Sbjct 578 PKAMKRLVADCVKKVKEERPLFPQILSSIELLQ 610
Score = 222 bits (565), Expect = 5e-60, Method: Composition-based stats.
Identities = 70/367 (19%), Positives = 127/367 (35%), Gaps = 62/367 (17%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
R + N I RG R S + ++ E+ + +G G+ VY+G+
Sbjct 316 RERAPGSGTQEKNKIRPRGQRDSSY--------YWEIEASEVMLSTRIGSGSFGTVYKGK 367
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQ 664
+ V +K+L DP+ + AF +++ +
Sbjct 368 WHGD---------------------------VAVKILKVVDPTPEQLQ-AFRNEVAVLRK 399
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
H ++ G + +VT++ E L L + M + +A+Q A + Y
Sbjct 400 TRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778
L KN++H ++ NI L +K+ D G+ G+ E+ + W
Sbjct 459 LHAKNIIHRDMKSNNIFLHEGL-------TVKIGDFGLATVKSRWSGSQQVEQPTGSVLW 511
Query 779 LAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------ 831
+APE + N S D + +G L E+ GE P + ++ F +
Sbjct 512 MAPEVIRMQDDNPFSFQSDVYSYGIVLYELMA-GELPYAHINNRDQIIFMVGRGYASPDL 570
Query 832 -RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
RL + + L + C+ +RP F IL + LQ + + S
Sbjct 571 SRLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAH 630
Query 891 VFHKRYL 897
Sbjct 631 TEDINAC 637
>sp|O65238|Y5537_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At5g35370 OS=Arabidopsis thaliana OX=3702
GN=At5g35370 PE=2 SV=2
Length=872
Score = 234 bits (598), Expect = 6e-63, Method: Composition-based stats.
Identities = 76/379 (20%), Positives = 125/379 (33%), Gaps = 59/379 (16%)
Query 471 YLIHWSTSHPYRLILTVAQRSQAPD--GMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRE 528
YL+ S L L V + D G L +RK + G SFP +
Sbjct 395 YLVKDS---FGSLSL-VKNSPENHDLIGYVKLSIRKTNAQPPGNN---NRGGSSFPVIAL 447
Query 529 LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL-------SQLSF 581
+ G L RRC + + + R L + F
Sbjct 448 VLLPCSGFFLLIALGLLWWRRCAVMRYSSIREKQVTRPGSFESGDLGSFHIPGLPQKFEF 507
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
++Q +G G +VY+G L E + +
Sbjct 508 EELEQATENFKMQIGSGGFGSVYKGTL-------------------------PDETLIAV 542
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
K + F +++ + HT+L + G C RG + ++V EY+ HG L+ L
Sbjct 543 KKITNHGLHGRQEFCTEIAIIGNIRHTNLVKLRGFCARGRQLLLVYEYMNHGSLEKTLFS 602
Query 702 ERGH-VPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
G + + +A A L+YL + + ++H +V NILL K+
Sbjct 603 GNGPVLEWQERFDIALGTARGLAYLHSGCDQKIIHCDVKPENILL-------HDHFQPKI 655
Query 758 SDPGVGLGALSRE-----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
SD G+ E +LAPE + A +S D + +G LLE+ +
Sbjct 656 SDFGLSKLLNQEESSLFTTMRGTRGYLAPEWITNAA--ISEKADVYSYGMVLLELVSGRK 713
Query 813 APLQSRSPSEKEHFYQRQH 831
+ + H
Sbjct 714 NCSFRSRSNSVTEDNNQNH 732
Score = 221 bits (563), Expect = 2e-58, Method: Composition-based stats.
Identities = 69/319 (22%), Positives = 121/319 (38%), Gaps = 36/319 (11%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ + + +G G FG V ++AVK + + G
Sbjct 496 FHIPGLPQKFEFEELEQATENFKMQIGSGGFGSVYKGTL-----PDETLIAVKKI-TNHG 549
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--- 994
R + EI I+ + H +++K +G C + L LV EY+ GSL L +
Sbjct 550 LHGRQEFCTEIAIIGNIRHTNLVKLRGFCARG--RQLLLVYEYMNHGSLEKTLFSGNGPV 607
Query 995 IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
+ + A G+AYLH+ Q IH D+ N+LL + KI DFGL+K +
Sbjct 608 LEWQERFDIALGTARGLAYLHSGCDQKIIHCDVKPENILLHDHFQPKISDFGLSKLL--N 665
Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC------------- 1098
E + + APE + +DV+S+G+ L EL++
Sbjct 666 QEESSLFTTMRGTRGYLAPEWITNAAISEKADVYSYGMVLLELVSGRKNCSFRSRSNSVT 725
Query 1099 -DSSQSPPTKFLELIGIAQGQMTVL------RLTELLERGERLPRPDKCPCEVYHLMKNC 1151
D++Q+ + G+ + L R EL + + ++ + C
Sbjct 726 EDNNQNHSSTTTTSTGLVYFPLYALDMHEQGRYMELADPRLEGRVTSQEAEKLVRIALCC 785
Query 1152 WETEASFRPTFENLIPILK 1170
E + RPT ++ + +
Sbjct 786 VHEEPALRPTMAAVVGMFE 804
>sp|Q03141|MARK3_MOUSE MAP/microtubule affinity-regulating kinase
3 OS=Mus musculus OX=10090 GN=Mark3 PE=1 SV=2
Length=753
Score = 233 bits (593), Expect = 6e-63, Method: Composition-based stats.
Identities = 76/280 (27%), Positives = 118/280 (42%), Gaps = 29/280 (10%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEID 949
H + ++ +G+G+F KV L + TG VA+K + K P +E+
Sbjct 50 QPHIGNYRLLKTIGKGNFAKVKL----ARHILTGREVAIKIIDKTQLNPTSLQKLFREVR 105
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQIC 1008
I++ L H +I+K E EK+L L+MEY G + DYL H + + +QI
Sbjct 106 IMKILNHPNIVKLFEVIE--TEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIV 163
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+ Y H + +HRDL A N+LLD D +KI DFG + G + + +
Sbjct 164 SAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGSKL----DTFCGSPPYA 219
Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + K+ DVWS GV LY L++ + L E
Sbjct 220 APELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD---------------GQNLKELRER 264
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ RG + P + +L+K R T E ++
Sbjct 265 VLRG-KYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMK 303
Score = 190 bits (483), Expect = 8e-49, Method: Composition-based stats.
Identities = 57/319 (18%), Positives = 106/319 (33%), Gaps = 41/319 (13%)
Query 556 GETSNLIIMRGARASPRTLN-LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
G+ + R R+ R N ++ + + L +G+G V R + G
Sbjct 22 GDGRQEVTSRTGRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGR- 80
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAF 672
V +K++D + + + +M ++H ++
Sbjct 81 -----------------------EVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 117
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVH 732
+ V ++ EY G + +L G + +Q+ SA+ Y K +VH
Sbjct 118 LFEVIETEKTLYLIMEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYCHQKRIVH 176
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGAN 789
++ N+LL IK++D G + P+ APE G
Sbjct 177 RDLKAENLLLD-------ADMNIKIADFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKY 229
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQC 848
+D W G L + G P ++ E R +R+P L +
Sbjct 230 D-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRF 287
Query 849 LTYEPTQRPSFRTILRDLT 867
L P +R + I++D
Sbjct 288 LVLNPVKRGTLEQIMKDRW 306
>sp|Q9LJD8|M3KE1_ARATH MAP3K epsilon protein kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=M3KE1 PE=1 SV=1
Length=1368
Score = 239 bits (609), Expect = 6e-63, Method: Composition-based stats.
Identities = 75/294 (26%), Positives = 132/294 (45%), Gaps = 28/294 (10%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ S + ++G+G +G+V Y + G+ VA+K + +
Sbjct 1 MARQMTSSQFHKSKTLDNKYMLGDEIGKGAYGRV----YKGLDLENGDFVAIKQVSLENI 56
Query 938 PQHR-SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996
Q + QEID+L+ L H++I+KY G + + L +++EYV GSL + + + G
Sbjct 57 VQEDLNTIMQEIDLLKNLNHKNIVKYLGS--SKTKTHLHIILEYVENGSLANIIKPNKFG 114
Query 997 ---LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ + ++ Q+ EG+ YLH Q IHRD+ N+L + LVK+ DFG+A + E
Sbjct 115 PFPESLVAVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGLVKLADFGVATKLNEAD- 173
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
+W APE ++ ASD+WS G T+ ELLT
Sbjct 174 --VNTHSVVGTPYWMAPEVIEMSGVCAASDIWSVGCTVIELLTCVPPYYD---------- 221
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
Q + R+ + + P PD ++ ++ C++ ++ RP + L+
Sbjct 222 -LQPMPALFRIVQ----DDNPPIPDSLSPDITDFLRQCFKKDSRQRPDAKTLLS 270
Score = 208 bits (530), Expect = 2e-53, Method: Composition-based stats.
Identities = 61/305 (20%), Positives = 108/305 (35%), Gaps = 43/305 (14%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
R + SQ + + +G+G VY+G G
Sbjct 3 RQMTSSQFHKSKTLDNKYMLGDEIGKGAYGRVYKGLDLENGDF----------------- 45
Query 632 DRGQELRVVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
V +K + + + + L+ ++H ++ G ++ EY
Sbjct 46 -------VAIKQVSLENIVQEDLNTIMQEIDLLKNLNHKNIVKYLGSSKTKTHLHIILEY 98
Query 690 VEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
VE+G L ++ + G P + V Q+ L YL + ++H ++ G NIL + GL
Sbjct 99 VENGSLANIIKPNKFGPFPESLVAVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGL- 157
Query 749 EGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+KL+D GV ++ V W+APE + + + A D W G T+
Sbjct 158 ------VKLADFGVATKLNEADVNTHSVVGTPYWMAPEVIEM--SGVCAASDIWSVGCTV 209
Query 805 LEICFDGEAPLQSRSPSEKEH--FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
+E+ P P +P+ P + QC + QRP +T+
Sbjct 210 IELLTC-VPPYYDLQPMPALFRIVQDDNPPIPDSLSPDITDFLRQCFKKDSRQRPDAKTL 268
Query 863 LRDLT 867
L
Sbjct 269 LSHPW 273
>sp|Q9LDI3|CIPKO_ARATH CBL-interacting serine/threonine-protein
kinase 24 OS=Arabidopsis thaliana OX=3702 GN=CIPK24 PE=1 SV=1
Length=446
Score = 224 bits (572), Expect = 7e-63, Method: Composition-based stats.
Identities = 66/262 (25%), Positives = 113/262 (43%), Gaps = 29/262 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959
+GEG F KV N TG+ VA+K + ++R K+EI I++ + H +I
Sbjct 16 TIGEGTFAKVKF----ARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPNI 71
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
++ + + +V+E+V G L D + + + ++ + QQ+ + +A+ H +
Sbjct 72 VRLYEVLASPSK--IYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKG 129
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N+LLD + +K+ DFGL+ EG E R + APE L +
Sbjct 130 VYHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVELLRTT---CGTPNYVAPEVLSGQGY 186
Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
A+D+WS GV L+ +L P +L G+ ++ + P
Sbjct 187 DGSAADIWSCGVILFVILAG-----YLPFSETDLPGL-YRKINAAEFS----------CP 230
Query 1138 DKCPCEVYHLMKNCWETEASFR 1159
EV L+ + R
Sbjct 231 PWFSAEVKFLIHRILDPNPKTR 252
Score = 175 bits (443), Expect = 8e-46, Method: Composition-based stats.
Identities = 56/293 (19%), Positives = 100/293 (34%), Gaps = 42/293 (14%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
RV + E+ +G+GT V R+ V +K
Sbjct 7 RVGKYEV--GRTIGEGTFAKV------------------------KFARNTDTGDNVAIK 40
Query 643 VLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
++ S + + S+M V H ++ ++ V + +V E+V G L +
Sbjct 41 IMAKSTILKNRMVDQIKREISIMKIVRHPNIVRLYEVLASPSKIYIVLEFVTGGELFDRI 100
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+G + + QQL A+++ K + H ++ N+LL T+ +K+SD
Sbjct 101 -VHKGRLEESESRKYFQQLVDAVAHCHCKGVYHRDLKPENLLLD-------TNGNLKVSD 152
Query 760 PGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ G ++APE L G +A D W G L I
Sbjct 153 FGLSALPQEGVELLRTTCGTPNYVAPEVLSGQGYD-GSAADIWSCGVILFVILAGYLPFS 211
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
++ P + P ++ L + L P R + I +D
Sbjct 212 ETDLPGLYRKINAAEFSCPPWFSAEVKFLIHRILDPNPKTRIQIQGIKKDPWF 264
>sp|A2BD05|NEK6_PIG Serine/threonine-protein kinase Nek6 OS=Sus
scrofa OX=9823 GN=NEK6 PE=3 SV=1
Length=313
Score = 220 bits (560), Expect = 7e-63, Method: Composition-based stats.
Identities = 61/285 (21%), Positives = 117/285 (41%), Gaps = 30/285 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTL 954
+ + +G G F +V Y T + VA+K ++ + R +EI +L+ L
Sbjct 45 FQIEKKIGRGQFSEV----YKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQL 100
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICE 1009
H +IIKY + E L +V+E G L + + I + + Q+C
Sbjct 101 NHPNIIKYLDSFIEDNE--LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCS 158
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ ++H++ +HRD+ NV + +VK+GD GL + ++ +
Sbjct 159 AVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFS---SETTAAHSLVGTPYYMS 215
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE + E + + SD+WS G LYE+ +M + L + +E
Sbjct 216 PERIHENGYNFKSDIWSLGCLLYEMAALQSPFYG-------------DKMNLFSLCQKIE 262
Query 1130 RGERLPRP-DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ + P P + ++ L+ C + + RP + + + +H
Sbjct 263 QCDYPPLPGEHYSEKLRELVSMCIYPDPNQRPDIGYVHQVARQMH 307
Score = 173 bits (438), Expect = 1e-46, Method: Composition-based stats.
Identities = 54/332 (16%), Positives = 108/332 (33%), Gaps = 41/332 (12%)
Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
+P G +NL G P R + +G+G + VY+ ++
Sbjct 8 MPHGGSPNNLCHTPGPAHPPDPQRHPNALSFRCSLADFQIEKKIGRGQFSEVYKATCLLD 67
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
+ E R +K L+ Q++H ++
Sbjct 68 RKTVALKKVQIFEMMDAKARQD------CVK---------------EIGLLKQLNHPNII 106
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDV---WLRRERGHVPMAWKMVVAQQLASALSYLENK 728
+ E +V E + G L + ++++ +P QL SA+ ++ ++
Sbjct 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 166
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER----VERIPWLAPECL 784
++H ++ N+ + G+ +KL D G+G S V +++PE +
Sbjct 167 RVMHRDIKPANVFITATGI-------VKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERI 219
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS----EKEHFYQRQHRLPEPSCPQ 840
+ D W G L E+ + +K E +
Sbjct 220 HENGYNF--KSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEK 277
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
L L S C+ +P QRP + + ++
Sbjct 278 LRELVSMCIYPDPNQRPDIGYVHQVARQMHVW 309
>sp|Q802A6|STK4_SQUAC Serine/threonine-protein kinase 3/4 OS=Squalus
acanthias OX=7797 GN=STK4 PE=2 SV=1
Length=491
Score = 226 bits (575), Expect = 7e-63, Method: Composition-based stats.
Identities = 67/304 (22%), Positives = 116/304 (38%), Gaps = 27/304 (9%)
Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE 925
+ +Q T + + LGEG +G V + + +G+
Sbjct 1 MEEVQRRQHPHPRRSLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSV----FKAIHKESGQ 56
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
+VA+K + + Q +EI I++ H++KY G + L +VMEY GS
Sbjct 57 VVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVKYYGSYFKNTD--LWIVMEYCGAGS 111
Query 986 LRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043
+ D + ++ ++ Q +G+ YLH IHRD+ A N+LL+N+ K+ DFG
Sbjct 112 VSDLIRIRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNNEGHAKLADFG 171
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
+A + + R FW APE ++E + +D+WS G++ E+
Sbjct 172 VAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGISAIEMAEGKPPYAD 228
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163
+ I R +P+ E +K C R
Sbjct 229 -IHPMRAIFMIPTNPPPTFR------------KPELWTDEFTDFVKQCLVKNPEQRAAAT 275
Query 1164 NLIP 1167
L+
Sbjct 276 QLLQ 279
Score = 203 bits (516), Expect = 6e-55, Method: Composition-based stats.
Identities = 61/315 (19%), Positives = 102/315 (32%), Gaps = 46/315 (15%)
Query 563 IMRGARASPRTL--NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620
+ R PR LS+ S + ++ L LG+G+ +V++ + G
Sbjct 4 VQRRQHPHPRRSLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQ------- 56
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680
V +K + + S+M Q H+ +G +
Sbjct 57 -----------------VVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKN 97
Query 681 PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNI 740
+ +V EY G + +R + + Q L YL +H ++ NI
Sbjct 98 TDLWIVMEYCGAGSVSDLIRIRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNI 157
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMD 796
LL G KL+D GV R + W+APE + + D
Sbjct 158 LLNNEG-------HAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQE--IGYNCVAD 208
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYE 852
W G + +E+ +G+ P P R PE + QCL
Sbjct 209 IWSLGISAIEMA-EGKPPYADIHPMRAIFMIPTNPPPTFRKPELWTDEFTDFVKQCLVKN 267
Query 853 PTQRPSFRTILRDLT 867
P QR + +L+
Sbjct 268 PEQRAAATQLLQHPF 282
>sp|Q9SI06|Y5573_ARATH Putative leucine-rich repeat receptor-like
serine/threonine-protein kinase At2g04300 OS=Arabidopsis
thaliana OX=3702 GN=At2g04300 PE=3 SV=2
Length=892
Score = 235 bits (599), Expect = 8e-63, Method: Composition-based stats.
Identities = 70/322 (22%), Positives = 131/322 (41%), Gaps = 21/322 (7%)
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918
FR + + + T+ + + K + LG+G FG V
Sbjct 544 FRKRKTPRNEVSRTSRSLDPTITTKNRRFTYSEVVKMTNNFEKILGKGGFGMVYHGT--- 600
Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978
E VAVK L ++ +K E+++L ++H++++ G C++ ++L L+
Sbjct 601 --VNDAEQVAVKMLSPSSSQGYKE-FKAEVELLLRVHHKNLVGLVGYCDEG--ENLSLIY 655
Query 979 EYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLL 1031
EY+ G L++++ + + L + +G+ YLH +HRD+ N+LL
Sbjct 656 EYMAKGDLKEHMLGNQGVSILDWKTRLKIVAESAQGLEYLHNGCKPPMVHRDVKTTNILL 715
Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091
D K+ DFGL+++ P E RV + PE + SDV+SFG+ L
Sbjct 716 DEHFQAKLADFGLSRSFPLEGET-RVDTVVAGTPGYLDPEYYRTNWLNEKSDVYSFGIVL 774
Query 1092 YELLT--HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149
E++T H + E +G+ +T + +++ L
Sbjct 775 LEIITNQHVINQSREKPHIAEWVGV---MLTKGDIKSIIDPKFSGDYDAGSVWRAVELAM 831
Query 1150 NCWETEASFRPTFENLIPILKT 1171
+C ++ RPT ++ L
Sbjct 832 SCVNPSSTGRPTMSQVVIELNE 853
Score = 211 bits (536), Expect = 6e-55, Method: Composition-based stats.
Identities = 71/347 (20%), Positives = 115/347 (33%), Gaps = 64/347 (18%)
Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRT 601
R+ P+ + + + T + ++ V + LG+G
Sbjct 539 ALFLVFRKRKTPR----NEVSRTSRSLDPTITTKNRRFTYSEVVKMTNNFEKILGKGGFG 594
Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL 661
VY G + +V +K+L PS F L
Sbjct 595 MVYHGTVNDAE-------------------------QVAVKMLSPSSSQGYKEFKAEVEL 629
Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLA 719
+ +V H +L + G C G ++ EY+ G L + +G + W ++ + + A
Sbjct 630 LLRVHHKNLVGLVGYCDEGENLSLIYEYMAKGDLKEHMLGNQGVSILDWKTRLKIVAESA 689
Query 720 SALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERV-- 773
L YL N +VH +V NILL KL+D G+ L E RV
Sbjct 690 QGLEYLHNGCKPPMVHRDVKTTNILLDE-------HFQAKLADFGLSRSFPLEGETRVDT 742
Query 774 ---ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR---SPSEKEHFY 827
+L PE N L+ D + FG LLEI + QSR +E
Sbjct 743 VVAGTPGYLDPEYYRT--NWLNEKSDVYSFGIVLLEIITNQHVINQSREKPHIAEWVGVM 800
Query 828 QRQHRLPEPSCPQLA------------TLTSQCLTYEPTQRPSFRTI 862
+ + P+ + L C+ T RP+ +
Sbjct 801 LTKGDIKSIIDPKFSGDYDAGSVWRAVELAMSCVNPSSTGRPTMSQV 847
>sp|C0LGR6|Y4291_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At4g29180 OS=Arabidopsis thaliana OX=3702
GN=At4g29180 PE=1 SV=2
Length=913
Score = 235 bits (599), Expect = 8e-63, Method: Composition-based stats.
Identities = 70/328 (21%), Positives = 134/328 (41%), Gaps = 27/328 (8%)
Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922
+R +++ + + + +G+G FG V L +
Sbjct 533 MRRESKIMYSGAYSGPLLPSGKRRFTYSEVSSITNNFNKVIGKGGFGIVYLGSLE----- 587
Query 923 TGEMVAVKALK------------ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970
G +AVK + + Q ++ E ++L T++H ++ + G C+D
Sbjct 588 DGTEIAVKMINDSSFGKSKGSSSSSSSSQVSKEFQVEAELLLTVHHRNLASFVGYCDDG- 646
Query 971 EKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA---QHYIHRDL 1024
+S+ L+ EY+ G+L+DYL + + + L A +G+ YLH +HRD+
Sbjct 647 -RSMALIYEYMANGNLQDYLSSENAEDLSWEKRLHIAIDSAQGLEYLHHGCRPPIVHRDV 705
Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084
N+LL+++ KI DFGL+K PE + V +P + PE +K SDV
Sbjct 706 KTANILLNDNLEAKIADFGLSKVFPEDDLSHVVTAVMGTP-GYVDPEYYNTFKLNEKSDV 764
Query 1085 WSFGVTLYELLTHCDSSQSPPTKF-LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE 1143
+SFG+ L EL+T S + ++ + + + + +++ +
Sbjct 765 YSFGIVLLELITGKRSIMKTDDGEKMNVVHYVEPFLKMGDIDGVVDPRLHGDFSSNSAWK 824
Query 1144 VYHLMKNCWETEASFRPTFENLIPILKT 1171
+ +C + RP ++ LK
Sbjct 825 FVEVAMSCVRDRGTNRPNTNQIVSDLKQ 852
Score = 190 bits (483), Expect = 3e-48, Method: Composition-based stats.
Identities = 49/275 (18%), Positives = 89/275 (32%), Gaps = 31/275 (11%)
Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
++ V +G+G VY G L + +
Sbjct 557 FTYSEVSSITNNFNKVIGKGGFGIVYLGSLEDGTEIAVKMINDSSFGKSKGSSSSSSSSQ 616
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
V + F A L+ V H +LA G C G ++ EY+ +G L +
Sbjct 617 V------------SKEFQVEAELLLTVHHRNLASFVGYCDDGRSMALIYEYMANGNLQDY 664
Query 699 LRRERGH-VPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPF 754
L E + ++ +A A L YL + +VH +V NILL +
Sbjct 665 LSSENAEDLSWEKRLHIAIDSAQGLEYLHHGCRPPIVHRDVKTANILLN-------DNLE 717
Query 755 IKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
K++D G+ + + ++ PE L+ D + FG LLE+
Sbjct 718 AKIADFGLSKVFPEDDLSHVVTAVMGTPGYVDPEYY--NTFKLNEKSDVYSFGIVLLELI 775
Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT 843
+ +++ + + + L +
Sbjct 776 TGKRSIMKTDDGEKMNVVHYVEPFLKMGDIDGVVD 810
>sp|Q08E52|PAK1_BOVIN Serine/threonine-protein kinase PAK 1 OS=Bos
taurus OX=9913 GN=PAK1 PE=1 SV=1
Length=544
Score = 227 bits (579), Expect = 8e-63, Method: Composition-based stats.
Identities = 68/372 (18%), Positives = 127/372 (34%), Gaps = 24/372 (6%)
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
G P E + + + + ++ + R+ + +
Sbjct 183 GTPPPVIAPRPEHTKSVYTRSVIEPLPITPTRDVATSPISPTENNTTPPDALTRNTEKQK 242
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ + K+ + +G+G G V Y + TG+ VA+K
Sbjct 243 KKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV----YTAMDVATGQEVAIK 298
Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
+ P+ + EI ++R + +I+ Y E L +VMEY+ GSL D +
Sbjct 299 QMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVV 355
Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
+ Q+ ++ + + +LH+ IHRD+ + N+LL D VK+ DFG +
Sbjct 356 TETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITP 415
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
R +W APE + + D+WS G+ E++ PP
Sbjct 416 ---EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI-----EGEPPYLNEN 467
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP-IL 1169
+ T L P+K + C E + R + + L+
Sbjct 468 PLRALYLIATNGT--------PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF 519
Query 1170 KTVHEKYQGQAP 1181
+ + P
Sbjct 520 LKIAKPLSSLTP 531
Score = 181 bits (458), Expect = 6e-47, Method: Composition-based stats.
Identities = 54/291 (19%), Positives = 97/291 (33%), Gaps = 44/291 (15%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+K+ T+ +GQG VY D V +K +
Sbjct 265 PKKKYTRFEKIGQGASGTVY------------------------TAMDVATGQEVAIKQM 300
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ +M + + ++ + G E +V EY+ G L +
Sbjct 301 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 358
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ V ++ AL +L + ++H ++ NILL G +KL+D G
Sbjct 359 CMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 411
Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
R V W+APE + A +D W G +E+ +GE P + +P
Sbjct 412 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMI-EGEPPYLNENP 468
Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ PE ++CL + +R S + +L+
Sbjct 469 LRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF 519
>sp|Q8GZ99|HPCA1_ARATH Leucine-rich repeat receptor protein kinase
HPCA1 OS=Arabidopsis thaliana OX=3702 GN=HPCA1 PE=1 SV=1
Length=953
Score = 236 bits (601), Expect = 8e-63, Method: Composition-based stats.
Identities = 71/259 (27%), Positives = 120/259 (46%), Gaps = 11/259 (4%)
Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982
G+++A+K Q +K EI++L ++H+++++ G C D+ E+ LV EY+
Sbjct 652 NGQLIAIKR-AQQGSLQGGLEFKTEIELLSRVHHKNVVRLLGFCFDRNEQ--MLVYEYIS 708
Query 983 LGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRL 1036
GSL+D L S + + L A +G+AYLH IHRD+ + N+LLD +
Sbjct 709 NGSLKDSLSGKSGIRLDWTRRLKIALGSGKGLAYLHELADPPIIHRDIKSNNILLDENLT 768
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
K+ DFGL+K V + + + V + + PE + SDV+ FGV L ELLT
Sbjct 769 AKVADFGLSKLVGDPEKTH-VTTQVKGTMGYLDPEYYMTNQLTEKSDVYGFGVVLLELLT 827
Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD-KCPCEVYHLMKNCWETE 1155
+ E+ ++ L ELL+ + K + L C E E
Sbjct 828 GRSPIERGKYVVREVKTKMNKSRSLYDLQELLDTTIIASSGNLKGFEKYVDLALRCVEEE 887
Query 1156 ASFRPTFENLIPILKTVHE 1174
RP+ ++ ++ + +
Sbjct 888 GVNRPSMGEVVKEIENIMQ 906
Score = 195 bits (495), Expect = 1e-49, Method: Composition-based stats.
Identities = 57/293 (19%), Positives = 101/293 (34%), Gaps = 28/293 (10%)
Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
+ + RA T + + + I +G T +E + +
Sbjct 581 ALRQKKRAERATGQNNPFAKWDTSKSSIDAPQLMGAKAFT--FEELKKCTDNFSEANDVG 638
Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
V + +K L F L+S+V H ++ + G C
Sbjct 639 GGGYGKVYRGILPNGQLIAIKRAQQGSLQGGLEFKTEIELLSRVHHKNVVRLLGFCFDRN 698
Query 682 ENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCG 737
E ++V EY+ +G L L + G + ++ +A L+YL ++H ++
Sbjct 699 EQMLVYEYISNGSLKDSLSGKSGIRLDWTRRLKIALGSGKGLAYLHELADPPIIHRDIKS 758
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSL 791
NILL + K++D G+ E+ + +L PE N L
Sbjct 759 NNILLDE-------NLTAKVADFGLSKLVGDPEKTHVTTQVKGTMGYLDPEYYMT--NQL 809
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATL 844
+ D +GFG LLE+ RSP E+ + R+ + L L
Sbjct 810 TEKSDVYGFGVVLLELLT-------GRSPIERGKYVVREVKTKMNKSRSLYDL 855
>sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase
3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5
Length=753
Score = 232 bits (592), Expect = 8e-63, Method: Composition-based stats.
Identities = 76/280 (27%), Positives = 118/280 (42%), Gaps = 29/280 (10%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEID 949
H + ++ +G+G+F KV L + TG VA+K + K P +E+
Sbjct 50 QPHIGNYRLLKTIGKGNFAKVKL----ARHILTGREVAIKIIDKTQLNPTSLQKLFREVR 105
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQIC 1008
I++ L H +I+K E EK+L L+MEY G + DYL H + + +QI
Sbjct 106 IMKILNHPNIVKLFEVIE--TEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIV 163
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+ Y H + +HRDL A N+LLD D +KI DFG + G + + +
Sbjct 164 SAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKL----DTFCGSPPYA 219
Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + K+ DVWS GV LY L++ + L E
Sbjct 220 APELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD---------------GQNLKELRER 264
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ RG + P + +L+K R T E ++
Sbjct 265 VLRG-KYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMK 303
Score = 190 bits (482), Expect = 1e-48, Method: Composition-based stats.
Identities = 57/319 (18%), Positives = 107/319 (34%), Gaps = 41/319 (13%)
Query 556 GETSNLIIMRGARASPRTLN-LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
G+ + R +R+ R N ++ + + L +G+G V R + G
Sbjct 22 GDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGR- 80
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAF 672
V +K++D + + + +M ++H ++
Sbjct 81 -----------------------EVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 117
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVH 732
+ V ++ EY G + +L G + +Q+ SA+ Y K +VH
Sbjct 118 LFEVIETEKTLYLIMEYASGGEVFDYLVAH-GRMKEKEARSKFRQIVSAVQYCHQKRIVH 176
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGAN 789
++ N+LL IK++D G + P+ APE G
Sbjct 177 RDLKAENLLLD-------ADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKY 229
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQC 848
+D W G L + G P ++ E R +R+P L +
Sbjct 230 D-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRF 287
Query 849 LTYEPTQRPSFRTILRDLT 867
L P +R + I++D
Sbjct 288 LVLNPIKRGTLEQIMKDRW 306
>sp|A8X775|DLK1_CAEBR Mitogen-activated protein kinase kinase
kinase dlk-1 OS=Caenorhabditis briggsae OX=6238 GN=dlk-1 PE=3
SV=1
Length=857
Score = 234 bits (597), Expect = 8e-63, Method: Composition-based stats.
Identities = 76/277 (27%), Positives = 119/277 (43%), Gaps = 34/277 (12%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ + LG G G V Y+ VAVK + + EI
Sbjct 55 WEIPFDAISNLEWLGSGSQGAVFHGQYE------NRTVAVKKVNQLK--------ETEIK 100
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQIC 1008
LR L H++II++ G C +VMEY P G L L + ++ Q+ + ++I
Sbjct 101 HLRHLRHKNIIEFLGVCSKS--PCYCIVMEYCPKGQLCTVLRQKNLITRQMFSDWVKEIA 158
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+GM YLH IHRDL + N+L+ + +KI DFG + + V W
Sbjct 159 DGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTSHLQKKND---STMMSFCGTVSWM 215
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
APE +K+ DV+SFGV L+E+LT ++P ++ I +L
Sbjct 216 APEMIKKEPCNEKVDVYSFGVVLWEMLTR----ETPYANIAQMAIIFGVGTNILN----- 266
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
LP P++ P + L+K C + RP+F ++
Sbjct 267 -----LPMPEEAPRGLVLLIKQCLSQKGRNRPSFSHI 298
Score = 199 bits (506), Expect = 3e-51, Method: Composition-based stats.
Identities = 58/348 (17%), Positives = 110/348 (32%), Gaps = 51/348 (15%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+ + ++ + I+ L LG G++ V+ G+
Sbjct 40 GGKPTQEIEKTEDEGWEIPFDAISNLEWLGSGSQGAVFHGQ------------------- 80
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+ V +K ++ + + H ++ GVC + P +V
Sbjct 81 -------YENRTVAVKKVNQLKE-------TEIKHLRHLRHKNIIEFLGVCSKSPCYCIV 126
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
EY G L LR ++ + +++A + YL ++H ++ NIL++
Sbjct 127 MEYCPKGQLCTVLR-QKNLITRQMFSDWVKEIADGMHYLHQNKVIHRDLKSPNILIS--- 182
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV----ERIPWLAPECLPGGANSLSTAMDKWGFGA 802
IK+ D G + + + W+APE + + +D + FG
Sbjct 183 ----AEDSIKICDFGTSHLQKKNDSTMMSFCGTVSWMAPEMIK--KEPCNEKVDVYSFGV 236
Query 803 TLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859
L E+ E P + + +PE + L L QCL+ + RPSF
Sbjct 237 VLWEMLTR-ETPYANIAQMAIIFGVGTNILNLPMPEEAPRGLVLLIKQCLSQKGRNRPSF 295
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
I + +P + S G
Sbjct 296 SHIRQHWEIFKPELFEMTEDEWQVAWDSYREFAKAIQYPSTVTKDHGG 343
>sp|Q9HC98|NEK6_HUMAN Serine/threonine-protein kinase Nek6 OS=Homo
sapiens OX=9606 GN=NEK6 PE=1 SV=2
Length=313
Score = 219 bits (559), Expect = 9e-63, Method: Composition-based stats.
Identities = 62/285 (22%), Positives = 116/285 (41%), Gaps = 30/285 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTL 954
+ + +G G F +V Y T + VA+K ++ + R +EI +L+ L
Sbjct 45 FQIEKKIGRGQFSEV----YKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQL 100
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICE 1009
H +IIKY + E L +V+E G L + + I + + Q+C
Sbjct 101 NHPNIIKYLDSFIEDNE--LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCS 158
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ ++H++ +HRD+ NV + +VK+GD GL + ++ +
Sbjct 159 AVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFS---SETTAAHSLVGTPYYMS 215
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE + E + + SD+WS G LYE+ +M + L + +E
Sbjct 216 PERIHENGYNFKSDIWSLGCLLYEMAALQSPFYG-------------DKMNLFSLCQKIE 262
Query 1130 RGERLPRP-DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ + P P + ++ L+ C + RP + + K +H
Sbjct 263 QCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDIGYVHQVAKQMH 307
Score = 174 bits (441), Expect = 6e-47, Method: Composition-based stats.
Identities = 54/333 (16%), Positives = 109/333 (33%), Gaps = 41/333 (12%)
Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
+P G ++NL G P R + +G+G + VY+ ++
Sbjct 8 MPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLD 67
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
+ E R +K L+ Q++H ++
Sbjct 68 RKTVALKKVQIFEMMDAKARQD------CVK---------------EIGLLKQLNHPNII 106
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDV---WLRRERGHVPMAWKMVVAQQLASALSYLENK 728
+ E +V E + G L + ++++ +P QL SA+ ++ ++
Sbjct 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 166
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER----VERIPWLAPECL 784
++H ++ N+ + G+ +KL D G+G S V +++PE +
Sbjct 167 RVMHRDIKPANVFITATGV-------VKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERI 219
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS----EKEHFYQRQHRLPEPSCPQ 840
+ D W G L E+ + +K E +
Sbjct 220 HENGYNF--KSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEK 277
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
L L S C+ +P QRP + + ++
Sbjct 278 LRELVSMCICPDPHQRPDIGYVHQVAKQMHIWM 310
>sp|Q55GE6|ROCO7_DICDI Probable serine/threonine-protein kinase
roco7 OS=Dictyostelium discoideum OX=44689 GN=roco7 PE=3 SV=1
Length=2615
Score = 239 bits (610), Expect = 9e-63, Method: Composition-based stats.
Identities = 74/329 (22%), Positives = 138/329 (42%), Gaps = 36/329 (11%)
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920
I L+ L ++ +V LK LG G + V +
Sbjct 1739 IIHETLSPRTTKIDIYSLAFEVTFNSNKFSVIPYETLKFGPQLGSGSYANVYRGIW---- 1794
Query 921 DGTGEMVAVKALKADCG----PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976
G VA+K L D G + ++ E I L H + + G L
Sbjct 1795 --NGSEVAIKVLNFDDGHANTTEKYREFRNEAHITGELRHANTVSLMGVSLS----PFCL 1848
Query 977 VMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD 1032
V E + G L ++ + +L A + +GM +LH+ +HRDL + N+LL
Sbjct 1849 VTELLQYGDLAKFIRNTAETFSWGTVLKLAIDVAKGMNFLHSCKPMIVHRDLKSANILLG 1908
Query 1033 ----NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
++ + K+GDFGL+ P G E V+ W APEC+ + ++ D++S+
Sbjct 1909 GSSMDNLVAKVGDFGLS-IKPIGKE---VKGRKVWNWRWLAPECMGDGQYTEKIDIYSYA 1964
Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148
+ L+E++T P ++++ + + + + +G R P++CP ++ L+
Sbjct 1965 IVLWEIITR----DLPFEEYVDQLKW------NSIIEDKIMKGLRPTIPNECPPDMKQLI 2014
Query 1149 KNCWETEASFRPTFENLIPILKTVHEKYQ 1177
+CW + RP+F +++ L T+ + +
Sbjct 2015 TDCWSGDPKKRPSFNSILERLSTMQKTFN 2043
Score = 209 bits (533), Expect = 2e-53, Method: Composition-based stats.
Identities = 63/315 (20%), Positives = 122/315 (39%), Gaps = 49/315 (16%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
+ + F + + + LG G+ NVY G
Sbjct 1758 FEVTFNSNKFSVIPYETLKFGPQLGSGSYANVYRGIWNGS-------------------- 1797
Query 632 DRGQELRVVLKVLD-----PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
V +KVL+ + + F A + ++ H + + GV + +V
Sbjct 1798 ------EVAIKVLNFDDGHANTTEKYREFRNEAHITGELRHANTVSLMGVSL--SPFCLV 1849
Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLAR 744
TE +++G L ++R + +A +A +++L + +VH ++ NILL
Sbjct 1850 TELLQYGDLAKFIRNTAETFSWGTVLKLAIDVAKGMNFLHSCKPMIVHRDLKSANILL-- 1907
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGFG 801
G + + K+ D G+ + + +E + ++ WLAPEC+ G + +D + +
Sbjct 1908 -GGSSMDNLVAKVGDFGLSIKPIGKEVKGRKVWNWRWLAPECMGDG--QYTEKIDIYSYA 1964
Query 802 ATLLEICFDGEAPL------QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855
L EI + S E + + +P P + L + C + +P +
Sbjct 1965 IVLWEIITRDLPFEEYVDQLKWNSIIEDKIMKGLRPTIPNECPPDMKQLITDCWSGDPKK 2024
Query 856 RPSFRTILRDLTRLQ 870
RPSF +IL L+ +Q
Sbjct 2025 RPSFNSILERLSTMQ 2039
>sp|A0A1D6E0S8|WAK17_MAIZE Wall-associated receptor kinase 17
OS=Zea mays OX=4577 GN=WAK17 PE=1 SV=1
Length=856
Score = 234 bits (597), Expect = 9e-63, Method: Composition-based stats.
Identities = 71/282 (25%), Positives = 114/282 (40%), Gaps = 18/282 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G G V +VA+K K + EI IL + H +++K
Sbjct 533 LGRGGQGTVYKGIL-----PDQTVVAIKKSKV-FDESQVEQFVNEIAILSQIDHPNVVKL 586
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----SIGLAQLLLFAQQICEGMAYLHAQ- 1017
GCC + + LV E++ G+L ++ + L A + + +AYLH+
Sbjct 587 LGCCLET--QVPLLVYEFISNGTLFQHIHNRNATRPLTWEDCLRIAAETADALAYLHSAS 644
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
IHRD+ + N+LLD + + KI DFG +++VP + G + + PE +
Sbjct 645 SIPIIHRDIKSSNILLDGNFVAKIADFGASRSVPFDQTHITTLIQG--TIGYLDPEYFQS 702
Query 1076 YKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ SDV+SFGV L ELLT S + P L RL + +E
Sbjct 703 SQLTEKSDVYSFGVVLAELLTRQKPISAARPEDSCNLAMHLVVLFNKGRLLQEIEPHILA 762
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
+ V L C + RP + +L+ + +
Sbjct 763 EAGEDQCYAVAELSVRCLNVKGEERPAMVVVASVLQELRRSF 804
Score = 221 bits (563), Expect = 2e-58, Method: Composition-based stats.
Identities = 63/356 (18%), Positives = 129/356 (36%), Gaps = 61/356 (17%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
+ ++ LG+G + VY+G L + V +K
Sbjct 521 KAATDNYSESRILGRGGQGTVYKGIL-------------------------PDQTVVAIK 555
Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
F +++SQ+ H ++ + G C+ ++V E++ +G L +
Sbjct 556 KSKVFDESQVEQFVNEIAILSQIDHPNVVKLLGCCLETQVPLLVYEFISNGTLFQHIHNR 615
Query 703 RGHVPMAWK--MVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKL 757
P+ W+ + +A + A AL+YL + + ++H ++ NILL + K+
Sbjct 616 NATRPLTWEDCLRIAAETADALAYLHSASSIPIIHRDIKSSNILLD-------GNFVAKI 668
Query 758 SDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
+D G + + I +L PE ++ L+ D + FG L E+ +
Sbjct 669 ADFGASRSVPFDQTHITTLIQGTIGYLDPEYFQ--SSQLTEKSDVYSFGVVLAELLTRQK 726
Query 813 A-----PLQSRSPSEKEHFYQRQHRLPE------------PSCPQLATLTSQCLTYEPTQ 855
P S + + + RL + C +A L+ +CL + +
Sbjct 727 PISAARPEDSCNLAMHLVVLFNKGRLLQEIEPHILAEAGEDQCYAVAELSVRCLNVKGEE 786
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911
RP+ + L L+ D D + + +++L + R + +V
Sbjct 787 RPAMVVVASVLQELRRSFTIDQAVGIKDESIQENSEQEEKHLHESRSIPSLQSSEV 842
>sp|Q10056|SHK2_SCHPO Serine/threonine-protein kinase shk2 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=shk2 PE=3 SV=1
Length=589
Score = 228 bits (582), Expect = 9e-63, Method: Composition-based stats.
Identities = 77/329 (23%), Positives = 135/329 (41%), Gaps = 28/329 (9%)
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899
+ ++ + +T P + S T+ R + S + Y
Sbjct 261 HVESIMTGKVTKVPVKADSKNTLSRRM---------TDRQALAMLKDSVTSHDPVEYFNV 311
Query 900 IRDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
LG+G G V L G + VA+K++ C + + EI ++R H +
Sbjct 312 KHKLGQGASGSVYLAKVVGGKQLGIFDSVAIKSIDLQCQTR-KELILNEITVMRESIHPN 370
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I+ Y + E+ L +VMEY+ GSL D + + + AQ+ + C+G+ +LHA++
Sbjct 371 IVTYLDSFLVR-ERHLWVVMEYMNAGSLTDIIEKSKLTEAQIARICLETCKGIQHLHARN 429
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ + NVLLDN +KI DFG + R +W APE +K+ ++
Sbjct 430 IIHRDIKSDNVLLDNSGNIKITDFGFCARLS---NRTNKRVTMVGTPYWMAPEVVKQNEY 486
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
D+WS G+ + E++ + L IA+ L+ L+ +
Sbjct 487 GTKVDIWSLGIMIIEMI-ENEPPYLREDPIRALYLIAKNGTPTLKKPNLVSKN------- 538
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + +C + FR T L+
Sbjct 539 -----LKSFLNSCLTIDTIFRATAAELLT 562
Score = 184 bits (468), Expect = 7e-48, Method: Composition-based stats.
Identities = 54/268 (20%), Positives = 95/268 (35%), Gaps = 40/268 (15%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LGQG +VY ++ V G+ G V +K +D
Sbjct 314 KLGQGASGSVYLAKV-------------------VGGKQLGIFDSVAIKSIDLQCQTRKE 354
Query 654 AFYETASLMSQVSHTHLAFVHG-VCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
++M + H ++ VR +V EY+ G L + E+ + A
Sbjct 355 LILNEITVMRESIHPNIVTYLDSFLVRERHLWVVMEYMNAGSLTDII--EKSKLTEAQIA 412
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
+ + + +L +N++H ++ N+LL G IK++D G +R
Sbjct 413 RICLETCKGIQHLHARNIIHRDIKSDNVLLDNSG-------NIKITDFGFCARLSNRTNK 465
Query 771 --ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
V W+APE + N T +D W G ++E+ + E P P +
Sbjct 466 RVTMVGTPYWMAPEVVKQ--NEYGTKVDIWSLGIMIIEMIEN-EPPYLREDPIRALYLIA 522
Query 829 RQHRL----PEPSCPQLATLTSQCLTYE 852
+ P L + + CLT +
Sbjct 523 KNGTPTLKKPNLVSKNLKSFLNSCLTID 550
>sp|P47735|RLK5_ARATH Receptor-like protein kinase 5 OS=Arabidopsis
thaliana OX=3702 GN=RLK5 PE=1 SV=1
Length=999
Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats.
Identities = 80/321 (25%), Positives = 129/321 (40%), Gaps = 27/321 (8%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD----- 935
L + +G G GKV GE+VAVK L
Sbjct 667 RSFHKLHFSEHEIADCLDEKNVIGFGSSGKVYKVELRG-----GEVVAVKKLNKSVKGGD 721
Query 936 ----CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP 991
+R + E++ L T+ H+ I++ CC G+ L LV EY+P GSL D L
Sbjct 722 DEYSSDSLNRDVFAAEVETLGTIRHKSIVRLW-CCCSSGDCKL-LVYEYMPNGSLADVLH 779
Query 992 RHS-----IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFG 1043
+G + L A EG++YLH +HRD+ + N+LLD+D K+ DFG
Sbjct 780 GDRKGGVVLGWPERLRIALDAAEGLSYLHHDCVPPIVHRDVKSSNILLDSDYGAKVADFG 839
Query 1044 LAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
+AK G + + APE + + SD++SFGV L EL+T +
Sbjct 840 IAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEKSDIYSFGVVLLELVTGKQPTD 899
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
S ++ + L +++ L ++ +V H+ C RP+
Sbjct 900 S-ELGDKDMAKWVCTALDKCGLEPVIDPKLDLKFKEEIS-KVIHIGLLCTSPLPLNRPSM 957
Query 1163 ENLIPILKTVHEKYQGQAPSV 1183
++ +L+ V +P+
Sbjct 958 RKVVIMLQEVSGAVPCSSPNT 978
Score = 184 bits (466), Expect = 5e-46, Method: Composition-based stats.
Identities = 59/330 (18%), Positives = 104/330 (32%), Gaps = 64/330 (19%)
Query 509 QQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGAR 568
DG ++ V L L C S+ + A
Sbjct 608 DLDGLCRKITRSKNIGYVWILLTIFLLAGLVFVVGIVMFIAKCRKLRALKSSTL----AA 663
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
+ R+ + S H + + + + +G G+ VY+ LR
Sbjct 664 SKWRSFHKLHFSEHEIA-DCLDEKNVIGFGSSGKVYKVELRGGE---------------- 706
Query 629 PGRDRGQELRVVLKVLDPSHHDIALA----------FYETASLMSQVSHTHLAFVHGVCV 678
V +K L+ S F + + H + + C
Sbjct 707 ---------VVAVKKLNKSVKGGDDEYSSDSLNRDVFAAEVETLGTIRHKSIVRLWCCCS 757
Query 679 RGPENIMVTEYVEHGPLDVWLRRERGH---VPMAWKMVVAQQLASALSYLENK---NLVH 732
G ++V EY+ +G L L +R + ++ +A A LSYL + +VH
Sbjct 758 SGDCKLLVYEYMPNGSLADVLHGDRKGGVVLGWPERLRIALDAAEGLSYLHHDCVPPIVH 817
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG--------LGALSREERVERIPWLAPECL 784
+V NILL + K++D G+ + ++APE +
Sbjct 818 RDVKSSNILLD-------SDYGAKVADFGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYV 870
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAP 814
++ D + FG LLE+ G+ P
Sbjct 871 --YTLRVNEKSDIYSFGVVLLELV-TGKQP 897
>sp|Q9FIF0|LRK22_ARATH Putative L-type lectin-domain containing
receptor kinase II.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK22
PE=3 SV=3
Length=694
Score = 231 bits (588), Expect = 1e-62, Method: Composition-based stats.
Identities = 72/301 (24%), Positives = 127/301 (42%), Gaps = 19/301 (6%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+P + R ++ R LG G FGKV +G +AVK + +
Sbjct 356 NEYSPQRYSFRNLYKAIRGFRENRLLGAGGFGKVYKGEL-----PSGTQIAVKRVYHNA- 409
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--- 994
Q + EI + L H+++++ G C +GE L LV +Y+P GSL DYL +
Sbjct 410 EQGMKQYAAEIASMGRLRHKNLVQLLGYCRRKGE--LLLVYDYMPNGSLDDYLFNKNKLK 467
Query 995 -IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
+ +Q + + + + YLH + +HRD+ A N+LLD D ++GDFGLA+
Sbjct 468 DLTWSQRVNIIKGVASALLYLHEEWEQVVLHRDIKASNILLDADLNGRLGDFGLARFHDR 527
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFL 1109
G R + + APE +D+++FG + E++ P + +
Sbjct 528 GENLQATR--VVGTIGYMAPELTAMGVATTKTDIYAFGSFILEVVCGRRPVEPDRPPEQM 585
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
L+ L ++++ K + L C ++ RP+ ++I L
Sbjct 586 HLLKWVATCGKRDTLMDVVDSKL-GDFKAKEAKLLLKLGMLCSQSNPESRPSMRHIIQYL 644
Query 1170 K 1170
+
Sbjct 645 E 645
Score = 221 bits (563), Expect = 2e-59, Method: Composition-based stats.
Identities = 63/304 (21%), Positives = 114/304 (38%), Gaps = 62/304 (20%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+ LG G VY+G L ++ +K + +
Sbjct 375 FRENRLLGAGGFGKVYKGEL-------------------------PSGTQIAVKRVYHNA 409
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ + M ++ H +L + G C R E ++V +Y+ +G LD +L + +
Sbjct 410 EQGMKQYAAEIASMGRLRHKNLVQLLGYCRRKGELLLVYDYMPNGSLDDYLFNKNKLKDL 469
Query 709 AW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
W ++ + + +ASAL YL + ++H ++ NILL +L D G+
Sbjct 470 TWSQRVNIIKGVASALLYLHEEWEQVVLHRDIKASNILLD-------ADLNGRLGDFGLA 522
Query 764 LGA-----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
L V I ++APE G +T D + FG+ +LE+ G P++
Sbjct 523 RFHDRGENLQATRVVGTIGYMAPELTAMGVA--TTKTDIYAFGSFILEVVC-GRRPVEPD 579
Query 819 SPSEKEHF------YQRQHRLPEPSCPQLATLTSQ-----------CLTYEPTQRPSFRT 861
P E+ H ++ L + +L ++ C P RPS R
Sbjct 580 RPPEQMHLLKWVATCGKRDTLMDVVDSKLGDFKAKEAKLLLKLGMLCSQSNPESRPSMRH 639
Query 862 ILRD 865
I++
Sbjct 640 IIQY 643
>sp|Q9FLZ3|KIN12_ARATH SNF1-related protein kinase catalytic subunit
alpha KIN12 OS=Arabidopsis thaliana OX=3702 GN=KIN12
PE=2 SV=1
Length=494
Score = 225 bits (574), Expect = 1e-62, Method: Composition-based stats.
Identities = 75/274 (27%), Positives = 113/274 (41%), Gaps = 29/274 (11%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILR 952
+ + LG G F KV L + TG VA+K L ++EI ILR
Sbjct 17 PNYRIGKTLGHGSFAKVKLALHVA----TGHKVAIKILNRSKIKNMGIEIKVQREIKILR 72
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGM 1011
L H HII+ E + + +VMEYV G L DY+ + + + QQI G+
Sbjct 73 FLMHPHIIRQYEVIETPND--IYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGV 130
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
Y H +HRDL NVLLD+ +KI DFGL+ + +G + ++ SP + APE
Sbjct 131 EYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDG---HFLKTSCGSPN-YAAPE 186
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + D+WS GV LY LL + + E ++RG
Sbjct 187 VISGKPYGPDVDIWSCGVILYALLCGTLPFDDE---------------NIPNVFEKIKRG 231
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P+ L+ + + R + +
Sbjct 232 M-YTLPNHLSHFARDLIPRMLMVDPTMRISITEI 264
Score = 177 bits (448), Expect = 5e-46, Method: Composition-based stats.
Identities = 55/326 (17%), Positives = 96/326 (29%), Gaps = 40/326 (12%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
LG G+ V G +V +K+L+ S
Sbjct 18 NYRIGKTLGHGSFAKVKLALHVATGH------------------------KVAIKILNRS 53
Query 648 ---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ I + ++ + H H+ + V + +V EYV+ G L ++ E+G
Sbjct 54 KIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYI-VEKG 112
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + QQ+ S + Y +VH ++ N+LL IK+ D G+
Sbjct 113 KLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQC-------NIKIVDFGLSN 165
Query 765 GALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ + APE + G +D W G L + P+
Sbjct 166 VMHDGHFLKTSCGSPNYAAPEVISG--KPYGPDVDIWSCGVILYALLCGTLPFDDENIPN 223
Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
E + + LP L + L +PT R S I + L +
Sbjct 224 VFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPL 283
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGH 907
+ H
Sbjct 284 DTIDQAKKIEEEIIQNVVNIGFDRNH 309
>sp|Q6K4T4|SERK4_ORYSJ LRR receptor kinase SERK2 OS=Oryza sativa
subsp. japonica OX=39947 GN=SERK4 PE=3 SV=1
Length=607
Score = 229 bits (583), Expect = 1e-62, Method: Composition-based stats.
Identities = 75/328 (23%), Positives = 127/328 (39%), Gaps = 20/328 (6%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
+ + + + + A + LG+G FGKV
Sbjct 241 CKGRRKSHLREVFVDVAGEDDRRIAFGQLKRFAWRELQIATDNFSERNVLGQGGFGKVYK 300
Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
G +AVK L P + + +E++++ H +++K G C Q E+
Sbjct 301 GVL-----PDGTKIAVKRLTDYESPGGEAAFLREVELISVAVHRNLLKLIGFCTTQTER- 354
Query 974 LQLVMEYVPLGS----LRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLA 1025
LV ++ S LRD+ P + + A G+ YLH IHRD+
Sbjct 355 -LLVYPFMQNLSVAYRLRDFKPGEPVLNWPERKRVAIGTARGLEYLHEHCNPKIIHRDVK 413
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
A NVLLD D +GDFGLAK V + V + APE L K +DV+
Sbjct 414 AANVLLDEDFEPVVGDFGLAKLV--DVQKTSVTTQVRGTMGHIAPEYLSTGKSSERTDVF 471
Query 1086 SFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
+G+ L EL+T D S+ + L+ + +L +++R D+
Sbjct 472 GYGIMLLELVTGQRAIDFSRLEEEDDVLLLDHVKKLQREGQLGSIVDRNLNQNYDDEEVE 531
Query 1143 EVYHLMKNCWETEASFRPTFENLIPILK 1170
+ + C ++ RP+ ++ +L+
Sbjct 532 MMIQIALLCTQSSPEDRPSMSEVVRMLE 559
Score = 185 bits (470), Expect = 4e-48, Method: Composition-based stats.
Identities = 63/362 (17%), Positives = 113/362 (31%), Gaps = 67/362 (19%)
Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + ++ + ++ + LGQG VY+G L
Sbjct 268 QLKRFAWRELQIATDNFSERNVLGQGGFGKVYKGVLPDG--------------------- 306
Query 633 RGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
++ +K L D AF L+S H +L + G C E ++V +++
Sbjct 307 ----TKIAVKRLTDYESPGGEAAFLREVELISVAVHRNLLKLIGFCTTQTERLLVYPFMQ 362
Query 692 HGPLDVWLRRERGHVP---MAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745
+ + LR + P + VA A L YL ++H +V N+LL
Sbjct 363 NLSVAYRLRDFKPGEPVLNWPERKRVAIGTARGLEYLHEHCNPKIIHRDVKAANVLLDED 422
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800
+ D G+ ++ V + +APE L G + S D +G+
Sbjct 423 FEPV-------VGDFGLAKLVDVQKTSVTTQVRGTMGHIAPEYLSTGKS--SERTDVFGY 473
Query 801 GATLLEICFDGEAPLQSRSPSE--------KEHFYQRQ-----------HRLPEPSCPQL 841
G LLE+ A SR E + + + +
Sbjct 474 GIMLLELVTGQRAIDFSRLEEEDDVLLLDHVKKLQREGQLGSIVDRNLNQNYDDEEVEMM 533
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901
+ C P RPS ++R L + + + +R+
Sbjct 534 IQIALLCTQSSPEDRPSMSEVVRMLEGEGLAERWEEWQQVEVTRRQEYERMQRRFDWGED 593
Query 902 DL 903
+
Sbjct 594 SV 595
>sp|Q9C7S5|PSYR1_ARATH Tyrosine-sulfated glycopeptide receptor
1 OS=Arabidopsis thaliana OX=3702 GN=PSY1R PE=1 SV=1
Length=1095
Score = 236 bits (603), Expect = 1e-62, Method: Composition-based stats.
Identities = 66/286 (23%), Positives = 118/286 (41%), Gaps = 19/286 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V D G +AVK L D G + +K E+++L HE+++
Sbjct 809 IGCGGFGLVYKATLD-----NGTKLAVKKLTGDYGMMEKE-FKAEVEVLSRAKHENLVAL 862
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLH-- 1015
+G C + L+ ++ GSL +L + + + L + G+AY+H
Sbjct 863 QGYCVHDSAR--ILIYSFMENGSLDYWLHENPEGPAQLDWPKRLNIMRGASSGLAYMHQI 920
Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H +HRD+ + N+LLD + + DFGL++ + + V + + + PE +
Sbjct 921 CEPHIVHRDIKSSNILLDGNFKAYVADFGLSRLILPYRTH--VTTELVGTLGYIPPEYGQ 978
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ DV+SFGV + ELLT + P EL+ + E+ + R
Sbjct 979 AWVATLRGDVYSFGVVMLELLTGKRPMEVFRPKMSRELVAWVHTMKRDGKPEEVFDTLLR 1038
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
++ V + C RP + ++ LK + +
Sbjct 1039 ESGNEEAMLRVLDIACMCVNQNPMKRPNIQQVVDWLKNIEAEKNQN 1084
Score = 203 bits (517), Expect = 5e-52, Method: Composition-based stats.
Identities = 65/344 (19%), Positives = 128/344 (37%), Gaps = 67/344 (19%)
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615
+ S +++ +R + L + +L +Q + +G G VY+ L
Sbjct 773 KDISLVLLFGNSRYEVKDLTIFELLK---ATDNFSQANIIGCGGFGLVYKATL------- 822
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675
D G +L +K L + + F ++S+ H +L + G
Sbjct 823 ----------------DNGTKL--AVKKLTGDYGMMEKEFKAEVEVLSRAKHENLVALQG 864
Query 676 VCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLE---NKN 729
CV I++ ++E+G LD WL G + W ++ + + +S L+Y+ +
Sbjct 865 YCVHDSARILIYSFMENGSLDYWLHENPEGPAQLDWPKRLNIMRGASSGLAYMHQICEPH 924
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS-----REERVERIPWLAPECL 784
+VH ++ NILL A ++D G+ L E V + ++ PE
Sbjct 925 IVHRDIKSSNILLDGNFKAY-------VADFGLSRLILPYRTHVTTELVGTLGYIPPEY- 976
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP----- 839
G A + D + FG +LE+ G+ P++ P H + P
Sbjct 977 -GQAWVATLRGDVYSFGVVMLELL-TGKRPMEVFRPKMSRELVAWVHTMKRDGKPEEVFD 1034
Query 840 -------------QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
++ + C+ P +RP+ + ++ L ++
Sbjct 1035 TLLRESGNEEAMLRVLDIACMCVNQNPMKRPNIQQVVDWLKNIE 1078
>sp|Q9CAL3|CRK2_ARATH Cysteine-rich receptor-like protein kinase
2 OS=Arabidopsis thaliana OX=3702 GN=CRK2 PE=1 SV=1
Length=649
Score = 229 bits (585), Expect = 1e-62, Method: Composition-based stats.
Identities = 74/290 (26%), Positives = 123/290 (42%), Gaps = 26/290 (9%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-GWKQEIDILRTLY 955
LG+G FG V G +AVK L +HR+ + E++++ T+
Sbjct 325 FDNANKLGQGGFGTVYKGVL-----PDGRDIAVKRL--FFNNRHRATDFYNEVNMISTVE 377
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGM 1011
H+++++ GC E LV EY+ SL ++ ++ + EG+
Sbjct 378 HKNLVRLLGCSCSGPES--LLVYEYLQNKSLDRFIFDVNRGKTLDWQRRYTIIVGTAEGL 435
Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
YLH Q IHRD+ A N+LLD+ KI DFGLA++ + + G + +
Sbjct 436 VYLHEQSSVKIIHRDIKASNILLDSKLQAKIADFGLARSFQDDKSHISTAIAG--TLGYM 493
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE-LIGIAQGQMTVLRLTEL 1127
APE L + DV+SFGV + E++T +++S + + + LI A L ++
Sbjct 494 APEYLAHGQLTEMVDVYSFGVLVLEIVTGKQNTKSKMSDYSDSLITEAWKHFQSGELEKI 553
Query 1128 LERGERLP------RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ K V + C + S RP L+ +LK
Sbjct 554 YDPNLDWKSQYDSHIIKKEIARVVQIGLLCTQEIPSLRPPMSKLLHMLKN 603
Score = 214 bits (544), Expect = 3e-57, Method: Composition-based stats.
Identities = 58/260 (22%), Positives = 101/260 (39%), Gaps = 45/260 (17%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+LN + + + LGQG VY+G L
Sbjct 307 KDSSLNFKYSTLEK-ATGSFDNANKLGQGGFGTVYKGVL-------------------PD 346
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
GRD + +K L ++ A FY +++S V H +L + G GPE+++V EY
Sbjct 347 GRD------IAVKRLFFNNRHRATDFYNEVNMISTVEHKNLVRLLGCSCSGPESLLVYEY 400
Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744
+++ LD ++ + W + + A L YL + ++H ++ NILL
Sbjct 401 LQNKSLDRFIFDVNRGKTLDWQRRYTIIVGTAEGLVYLHEQSSVKIIHRDIKASNILLDS 460
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWG 799
A K++D G+ + + + ++APE L G L+ +D +
Sbjct 461 KLQA-------KIADFGLARSFQDDKSHISTAIAGTLGYMAPEYLAHG--QLTEMVDVYS 511
Query 800 FGATLLEICFDGEAPLQSRS 819
FG +LEI + S
Sbjct 512 FGVLVLEIVTGKQNTKSKMS 531
>sp|Q8RY65|NIK2_ARATH Protein NSP-INTERACTING KINASE 2 OS=Arabidopsis
thaliana OX=3702 GN=NIK2 PE=1 SV=1
Length=635
Score = 229 bits (584), Expect = 1e-62, Method: Composition-based stats.
Identities = 67/311 (22%), Positives = 120/311 (39%), Gaps = 15/311 (5%)
Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE 925
+ N ++ N +G+G FG V C G
Sbjct 281 FFDINEQNKEEMCLGNLRRFNFKELQSATSNFSSKNLVGKGGFGNVYKGCL-----HDGS 335
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
++AVK LK ++ E++++ H ++++ G C E+ LV Y+ GS
Sbjct 336 IIAVKRLKDINNGGGEVQFQTELEMISLAVHRNLLRLYGFCTTSSER--LLVYPYMSNGS 393
Query 986 LRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGD 1041
+ L + + A G+ YLH Q IHRD+ A N+LLD+ +GD
Sbjct 394 VASRLKAKPVLDWGTRKRIALGAGRGLLYLHEQCDPKIIHRDVKAANILLDDYFEAVVGD 453
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS- 1100
FGLAK + + V V APE L + +DV+ FG+ L EL+T +
Sbjct 454 FGLAKLLDHEESH--VTTAVRGTVGHIAPEYLSTGQSSEKTDVFGFGILLLELITGLRAL 511
Query 1101 -SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+ ++ + +L +++++ + E+ + C + R
Sbjct 512 EFGKAANQRGAILDWVKKLQQEKKLEQIVDKDLKSNYDRIEVEEMVQVALLCTQYLPIHR 571
Query 1160 PTFENLIPILK 1170
P ++ +L+
Sbjct 572 PKMSEVVRMLE 582
Score = 183 bits (465), Expect = 3e-47, Method: Composition-based stats.
Identities = 63/320 (20%), Positives = 113/320 (35%), Gaps = 64/320 (20%)
Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
NL + +F + + + +G+G NVY+G L
Sbjct 296 NLRRFNFKELQSATSNFSSKNLVGKGGFGNVYKGCLHDGSI------------------- 336
Query 633 RGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+ +K L ++ + F ++S H +L ++G C E ++V Y+
Sbjct 337 ------IAVKRLKDINNGGGEVQFQTELEMISLAVHRNLLRLYGFCTTSSERLLVYPYMS 390
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748
+G + L+ + + + +A L YL + ++H +V NILL A
Sbjct 391 NGSVASRLKA-KPVLDWGTRKRIALGAGRGLLYLHEQCDPKIIHRDVKAANILLDDYFEA 449
Query 749 EGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+ D G+ E V + +APE L G + S D +GFG
Sbjct 450 V-------VGDFGLAKLLDHEESHVTTAVRGTVGHIAPEYLSTGQS--SEKTDVFGFGIL 500
Query 804 LLEICF------DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT------------LT 845
LLE+ G+A Q + + Q++ +L + L + +
Sbjct 501 LLELITGLRALEFGKAANQRGAILDWVKKLQQEKKLEQIVDKDLKSNYDRIEVEEMVQVA 560
Query 846 SQCLTYEPTQRPSFRTILRD 865
C Y P RP ++R
Sbjct 561 LLCTQYLPIHRPKMSEVVRM 580
>sp|Q9FN37|PSKR2_ARATH Phytosulfokine receptor 2 OS=Arabidopsis
thaliana OX=3702 GN=PSKR2 PE=1 SV=1
Length=1036
Score = 236 bits (602), Expect = 1e-62, Method: Composition-based stats.
Identities = 76/330 (23%), Positives = 131/330 (40%), Gaps = 19/330 (6%)
Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911
+ TI L P + + + + + + +G G FG V
Sbjct 709 DRINDVDEETISGVSKALGPSKIVLFHSCGCKDLSVEELLKSTNNFSQANIIGCGGFGLV 768
Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
+ G AVK L DCG R ++ E++ L H++++ +G C+ +
Sbjct 769 YKANF-----PDGSKAAVKRLSGDCGQMERE-FQAEVEALSRAEHKNLVSLQGYCKHGND 822
Query 972 KSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLH---AQHYIHRD 1023
+ L+ ++ GSL +L ++ L AQ G+AYLH + IHRD
Sbjct 823 R--LLIYSFMENGSLDYWLHERVDGNMTLIWDVRLKIAQGAARGLAYLHKVCEPNVIHRD 880
Query 1024 LAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASD 1083
+ + N+LLD + DFGLA+ + + V D + + PE + D
Sbjct 881 VKSSNILLDEKFEAHLADFGLARLLRPYDTH--VTTDLVGTLGYIPPEYSQSLIATCRGD 938
Query 1084 VWSFGVTLYELLTHCDSSQSPPTKF-LELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
V+SFGV L EL+T + K +L+ R EL++ R ++
Sbjct 939 VYSFGVVLLELVTGRRPVEVCKGKSCRDLVSRVFQMKAEKREAELIDTTIRENVNERTVL 998
Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTV 1172
E+ + C + E RP E ++ L+ +
Sbjct 999 EMLEIACKCIDHEPRRRPLIEEVVTWLEDL 1028
Score = 206 bits (523), Expect = 7e-53, Method: Composition-based stats.
Identities = 59/322 (18%), Positives = 113/322 (35%), Gaps = 64/322 (20%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+Q + +G G VY+ + + +K L
Sbjct 750 STNNFSQANIIGCGGFGLVYKA-------------------------NFPDGSKAAVKRL 784
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-R 703
+ F +S+ H +L + G C G + +++ ++E+G LD WL
Sbjct 785 SGDCGQMEREFQAEVEALSRAEHKNLVSLQGYCKHGNDRLLIYSFMENGSLDYWLHERVD 844
Query 704 GHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
G++ + W ++ +AQ A L+YL N++H +V NILL A L+
Sbjct 845 GNMTLIWDVRLKIAQGAARGLAYLHKVCEPNVIHRDVKSSNILLDEKFEAH-------LA 897
Query 759 DPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
D G+ + V + ++ PE + D + FG LLE+ G
Sbjct 898 DFGLARLLRPYDTHVTTDLVGTLGYIPPEYSQSLIA--TCRGDVYSFGVVLLELV-TGRR 954
Query 814 PLQSRSPSEKEHFYQRQHRLP------------------EPSCPQLATLTSQCLTYEPTQ 855
P++ R ++ E + ++ + +C+ +EP +
Sbjct 955 PVEVCKGKSCRDLVSRVFQMKAEKREAELIDTTIRENVNERTVLEMLEIACKCIDHEPRR 1014
Query 856 RPSFRTILRDLTRLQPHNLADV 877
RP ++ L L ++
Sbjct 1015 RPLIEEVVTWLEDLPMESVQQQ 1036
>sp|Q6X4A2|CIPKV_ORYSJ CBL-interacting protein kinase 31 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK31 PE=1 SV=1
Length=449
Score = 224 bits (570), Expect = 1e-62, Method: Composition-based stats.
Identities = 65/290 (22%), Positives = 117/290 (40%), Gaps = 35/290 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959
+GEG F KV N E VA+K L + +HR ++EI ++ + H ++
Sbjct 25 TIGEGTFAKVRF----AKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHPNV 80
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
++ + + +V+EYV G L + + + + + QQ+ + Y H++
Sbjct 81 VRLFEVM--GSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHSRG 138
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N+LLD +K+ DFGL+ + + +P + APE +++ +
Sbjct 139 VYHRDLKLENLLLDASGNLKVSDFGLSALTEQVKADGLLHTTCGTPN-YVAPEVIEDRGY 197
Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
A+D+WS GV LY LL + ++ L + + + P
Sbjct 198 DGAAADIWSCGVILYVLLAGFLPFEDD---------------NIIALYKKISEA-QFTCP 241
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAPSVFS 1185
L+ + + R T ++ P K +G P VF
Sbjct 242 SWFSTGAKKLITRILDPNPTTRITISQILEDPWFK------KGYKPPVFD 285
Score = 172 bits (435), Expect = 9e-45, Method: Composition-based stats.
Identities = 57/320 (18%), Positives = 97/320 (30%), Gaps = 44/320 (14%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
LS RV + E+ +G+GT V ++
Sbjct 9 LSPKVKRRVGKYEL--GRTIGEGTFAKV------------------------RFAKNTEN 42
Query 636 ELRVVLKVLDPSHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
+ V +K+LD + M V H ++ + V +V EYV
Sbjct 43 DEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHPNVVRLFEVMGSKARIFIVLEYVTG 102
Query 693 GPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752
G L + G + QQL +A+ Y ++ + H ++ N+LL S
Sbjct 103 GELFEIIATN-GRLKEEEARKYFQQLINAVDYCHSRGVYHRDLKLENLLLD-------AS 154
Query 753 PFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+K+SD G+ + ++APE + A D W G L
Sbjct 155 GNLKVSDFGLSALTEQVKADGLLHTTCGTPNYVAPEVIEDRGYD-GAAADIWSCGVILYV 213
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
+ + + + Q P L ++ L PT R + IL D
Sbjct 214 LLAGFLPFEDDNIIALYKKISEAQFTCPSWFSTGAKKLITRILDPNPTTRITISQILEDP 273
Query 867 TRLQPHNLADVLTVNPDSPA 886
+ + S
Sbjct 274 WFKKGYKPPVFDEKYETSFD 293
>sp|O14305|SID1_SCHPO Serine/threonine-protein kinase sid1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=sid1 PE=1 SV=1
Length=471
Score = 224 bits (572), Expect = 1e-62, Method: Composition-based stats.
Identities = 64/280 (23%), Positives = 121/280 (43%), Gaps = 25/280 (9%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
+ +R LG G FG V + + +G+++A+K + + G + +QE+
Sbjct 1 MYPLNANSYTLLRKLGSGSFGVV----WKARENVSGDIIAIKQIDLETGIDDITDIEQEV 56
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008
+L ++I+Y GC D +L ++ME++ GS+ L + + + +++
Sbjct 57 FMLSNCNSSNVIQYYGCFVDG--YTLWILMEHMDGGSVSGLLKMGRLNEQVISIILREVL 114
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
G+ YLH Q+ IHRD+ A N+LL + VK+ DFG+A + R FW
Sbjct 115 YGLNYLHGQNKIHRDIKAANILLSSSTGNVKLADFGVAAQLSNAASR---RHTFVGTPFW 171
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE +++ + A+D+WS G+T E+ + M +R+
Sbjct 172 MAPEVIQQTSYGLAADIWSLGITAIEMANGIPP---------------RATMHPMRVIFE 216
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + E D + C + + R + + L+
Sbjct 217 IPQSEPPKLDDHFSPTFRDFVSCCLDLNPNMRWSAKELLQ 256
Score = 192 bits (488), Expect = 2e-51, Method: Composition-based stats.
Identities = 59/291 (20%), Positives = 112/291 (38%), Gaps = 42/291 (14%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
++ T L LG G+ V++ R V G + +K
Sbjct 4 LNANSYTLLRKLGSGSFGVVWKARENVSGD------------------------IIAIKQ 39
Query 644 LD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+D + D + ++S + +++ +G V G ++ E+++ G + L+
Sbjct 40 IDLETGIDDITDIEQEVFMLSNCNSSNVIQYYGCFVDGYTLWILMEHMDGGSVSGLLKM- 98
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG- 761
G + ++ +++ L+YL +N +H ++ NILL+ ++ +KL+D G
Sbjct 99 -GRLNEQVISIILREVLYGLNYLHGQNKIHRDIKAANILLSS------STGNVKLADFGV 151
Query 762 ---VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ A R V W+APE + S A D W G T +E+ +G P +
Sbjct 152 AAQLSNAASRRHTFVGTPFWMAPEVIQQ--TSYGLAADIWSLGITAIEMA-NGIPPRATM 208
Query 819 SPSEKEHFYQRQ--HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
P + +L + P S CL P R S + +L+
Sbjct 209 HPMRVIFEIPQSEPPKLDDHFSPTFRDFVSCCLDLNPNMRWSAKELLQHPF 259
>sp|Q00372|SNF1_CANGA Carbon catabolite-derepressing protein kinase
OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM
3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=SNF1
PE=3 SV=2
Length=612
Score = 228 bits (582), Expect = 1e-62, Method: Composition-based stats.
Identities = 74/276 (27%), Positives = 114/276 (41%), Gaps = 31/276 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG--WKQEIDILRT 953
+ ++ LGEG FGKV L + TG+ VA+K + + ++EI LR
Sbjct 38 NYQIVKTLGEGSFGKVKLAY----HVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRL 93
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012
L H HIIK + + E + +V+EY L DY+ R+ + + F QQI +
Sbjct 94 LRHPHIIKLYDVIKSKDE--IIMVIEYAGN-ELFDYIVQRNKMSEQEARRFFQQIISAVE 150
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Y H +HRDL N+LLD VKI DFGL+ + +G+ ++ SP + APE
Sbjct 151 YCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGN---FLKTSCGSPN-YAAPEV 206
Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + DVWS GV LY +L ++ L + + G
Sbjct 207 ISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDE---------------SIPVLFKNISNG 251
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P L+K R + ++
Sbjct 252 V-YTLPKFLSPGASDLIKRMLIVNPLNRISIHEIMQ 286
Score = 180 bits (457), Expect = 3e-46, Method: Composition-based stats.
Identities = 53/287 (18%), Positives = 95/287 (33%), Gaps = 40/287 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ LG+G+ V G +V LK+++
Sbjct 38 NYQIVKTLGEGSFGKVKLAYHVTTGQ------------------------KVALKIINKK 73
Query 648 ---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D+ S + + H H+ ++ V E IMV EY + L ++ +R
Sbjct 74 VLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGN-ELFDYI-VQRN 131
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ QQ+ SA+ Y +VH ++ N+LL +K++D G+
Sbjct 132 KMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDE-------HLNVKIADFGLSN 184
Query 765 GALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ + APE + G + +D W G L + P
Sbjct 185 IMTDGNFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYVMLCRRLPFDDESIPV 243
Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
++ + LP+ P + L + L P R S I++D
Sbjct 244 LFKNISNGVYTLPKFLSPGASDLIKRMLIVNPLNRISIHEIMQDEWF 290
>sp|Q9UEW8|STK39_HUMAN STE20/SPS1-related proline-alanine-rich
protein kinase OS=Homo sapiens OX=9606 GN=STK39 PE=1 SV=3
Length=545
Score = 227 bits (578), Expect = 1e-62, Method: Composition-based stats.
Identities = 71/290 (24%), Positives = 118/290 (41%), Gaps = 24/290 (8%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ + +G G V P E VA+K + + +EI
Sbjct 56 WPICRDAYELQEVIGSGATAVVQAALCKPRQ----ERVAIKRINLEKCQTSMDELLKEIQ 111
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---------RHSIGLAQL 1000
+ H +++ Y + E L LVM+ + GS+ D + + A +
Sbjct 112 AMSQCSHPNVVTYYTSFVVKDE--LWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAII 169
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--VR 1058
+++ EG+ YLH IHRDL A N+LL D V+I DFG++ + G + R VR
Sbjct 170 ATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVR 229
Query 1059 EDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
+ W APE +++ + + +D+WSFG+T EL T P + ++ +
Sbjct 230 KTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTL--- 286
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
Q L +E E + K L+ C + + S RPT L+
Sbjct 287 QNDPPTLETGVEDKEMM---KKYGKSFRKLLSLCLQKDPSKRPTAAELLK 333
Score = 173 bits (439), Expect = 2e-44, Method: Composition-based stats.
Identities = 60/354 (17%), Positives = 122/354 (34%), Gaps = 52/354 (15%)
Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+ ++ RV +K ++ ++ + MSQ SH ++ + V E +V + +
Sbjct 83 KPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLS 142
Query 692 HGPLDVWLR-------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
G + ++ + G + A + +++ L YL +H ++ NILL
Sbjct 143 GGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGE 202
Query 745 LGLAEGTSPFIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAM 795
G ++++D GV + R+ V W+APE +
Sbjct 203 DG-------SVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKA 254
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-----------HRLPEPSCPQLATL 844
D W FG T +E+ G AP P + + + + L
Sbjct 255 DMWSFGITAIELA-TGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKL 313
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
S CL +P++RP+ +L+ + + P + + +
Sbjct 314 LSLCLQKDPSKRPTAAELLKCKFF---QKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGS 370
Query 905 EGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
GH K ++ ++D E + ++ + QE R + E+
Sbjct 371 SGHLHKTEDGDWEWSDDEMDEK----------SEEGKAAFSQEKS--RRVKEEN 412
>sp|Q19238|YS3J_CAEEL Putative tyrosine-protein kinase F09A5.2
OS=Caenorhabditis elegans OX=6239 GN=F09A5.2 PE=3 SV=3
Length=867
Score = 234 bits (596), Expect = 1e-62, Method: Composition-based stats.
Identities = 89/357 (25%), Positives = 145/357 (41%), Gaps = 56/357 (16%)
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY--LKKIRD 902
+ + + + N + ++ D + +++
Sbjct 413 MRKKFNKDVENGSCKELNTQKWSHFASANNYMDIQALANANKKDIWEIDTKNLLVQEDHL 472
Query 903 LGEGHFGKVSLYCYDPT------NDGTGEMV----------AVKALKADCGPQHRSGWKQ 946
LG G F V N+ V A+K L A Q+ +
Sbjct 473 LGNGAFANVYKGIVKGKIPLLVVNNSLNMTVESENNGHYEAAIKKLPAHADEQNHLDFFH 532
Query 947 EIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------- 994
EID ++ L +H H+I GC + E +V+EY G L +L RH
Sbjct 533 EIDFMKRLGHHPHVISMLGCVSNPYEP--LIVVEYCARGDLLKFLRRHKDYVLMNKTDDC 590
Query 995 -------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
+ + L+ A Q+ +GM+YL ++++IHRDLAARN+LL K+ DFGL +
Sbjct 591 PIEADMCLRIKDLVSIAWQVADGMSYLASKNFIHRDLAARNILLTKSLTAKVSDFGLCRY 650
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
+ + G P+ W + E LK Y+F +DVWSFGV L+E+ + D
Sbjct 651 M---DSALYTAKGGRLPIKWMSVEALKLYEFSTKTDVWSFGVLLFEIFSMGD-------- 699
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ + + + E L G RL +P KCP E++++M+ CW + RP F
Sbjct 700 ------VPYPTIQQVDMLEHLLAGGRLSQPLKCPNEIFNIMQKCWAEKPEDRPEFNE 750
Score = 225 bits (573), Expect = 1e-59, Method: Composition-based stats.
Identities = 76/321 (24%), Positives = 127/321 (40%), Gaps = 39/321 (12%)
Query 575 NLSQLSFHRVDQKEI--TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
N ++ +D K + + LG G NVY+G ++ G +++ + +
Sbjct 451 NANKKDIWEIDTKNLLVQEDHLLGNGAFANVYKGIVK----GKIPLLVVNNSLNMTVESE 506
Query 633 RGQELRVVLKVLDP-SHHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690
+K L + L F+ M ++ H H+ + G E ++V EY
Sbjct 507 NNGHYEAAIKKLPAHADEQNHLDFFHEIDFMKRLGHHPHVISMLGCVSNPYEPLIVVEYC 566
Query 691 EHGPLDVWLRRERGHVPMAW----------------KMVVAQQLASALSYLENKNLVHGN 734
G L +LRR + +V M + +A Q+A +SYL +KN +H +
Sbjct 567 ARGDLLKFLRRHKDYVLMNKTDDCPIEADMCLRIKDLVSIAWQVADGMSYLASKNFIHRD 626
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER----IPWLAPECLPGGANS 790
+ RNILL + S K+SD G+ S + I W++ E L
Sbjct 627 LAARNILLTK-------SLTAKVSDFGLCRYMDSALYTAKGGRLPIKWMSVEALK--LYE 677
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQC 848
ST D W FG L EI G+ P + + RL +P CP + + +C
Sbjct 678 FSTKTDVWSFGVLLFEIFSMGDVPYPTIQQVDMLEHLLAGGRLSQPLKCPNEIFNIMQKC 737
Query 849 LTYEPTQRPSFRTILRDLTRL 869
+P RP F + ++T +
Sbjct 738 WAEKPEDRPEFNEMRGEITVM 758
>sp|P51956|NEK3_HUMAN Serine/threonine-protein kinase Nek3 OS=Homo
sapiens OX=9606 GN=NEK3 PE=1 SV=2
Length=506
Score = 226 bits (575), Expect = 1e-62, Method: Composition-based stats.
Identities = 67/277 (24%), Positives = 119/277 (43%), Gaps = 27/277 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+R +GEG FG+ L ++ + +M A+K ++ + ++E +L
Sbjct 1 MDDYMVLRMIGEGSFGRALLVQHE----SSNQMFAMKEIRLPKSFSNTQNSRKEAVLLAK 56
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEG 1010
+ H +I+ +K E E L +VMEY G L + + +L + Q+C G
Sbjct 57 MKHPNIVAFKESFE--AEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLG 114
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
+ ++H + +HRD+ ++N+ L + VK+GDFG A+ + + ++ P
Sbjct 115 VNHIHKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACT---YVGTPYYVPP 171
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E + + SD+WS G LYEL T Q+ K L L + +
Sbjct 172 EIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWKNLIL---------------KVCQ 216
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
G P P E+ L+K ++ S RP+ L+
Sbjct 217 GCISPLPSHYSYELQFLVKQMFKRNPSHRPSATTLLS 253
Score = 155 bits (392), Expect = 1e-38, Method: Composition-based stats.
Identities = 46/284 (16%), Positives = 92/284 (32%), Gaps = 40/284 (14%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ L +G+G+ + + +K +
Sbjct 1 MDDYMVLRMIGEGSFGR------------------------ALLVQHESSNQMFAMKEIR 36
Query 646 -PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
P + A L++++ H ++ +V EY + G L +++++G
Sbjct 37 LPKSFSNTQNSRKEAVLLAKMKHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKG 96
Query 705 HV-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ P + Q+ ++++ K ++H ++ +NI L + G +KL D G
Sbjct 97 KLFPEDMILNWFTQMCLGVNHIHKKRVLHRDIKSKNIFLTQNG-------KVKLGDFGSA 149
Query 764 LGALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ V ++ PE + D W G L E+C +
Sbjct 150 RLLSNPMAFACTYVGTPYYVPPEIWEN--LPYNNKSDIWSLGCILYELCTLKHPFQANSW 207
Query 820 PSEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
+ Q LP +L L Q P+ RPS T+
Sbjct 208 KNLILKVCQGCISPLPSHYSYELQFLVKQMFKRNPSHRPSATTL 251
>sp|Q9FII5|TDR_ARATH Leucine-rich repeat receptor-like protein
kinase TDR OS=Arabidopsis thaliana OX=3702 GN=TDR PE=1 SV=1
Length=1041
Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats.
Identities = 74/301 (25%), Positives = 125/301 (42%), Gaps = 28/301 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-----SGWKQEIDILRTLYHE 957
LG G G V GE++AVK L + SG E+D+L + H
Sbjct 725 LGMGSTGTVYKA-----EMPNGEIIAVKKLWGKNKENGKIRRRKSGVLAEVDVLGNVRHR 779
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG------LAQLLLFAQQICEGM 1011
+I++ GCC ++ L+ EY+P GSL D L L A + +G+
Sbjct 780 NIVRLLGCCTNRD--CTMLLYEYMPNGSLDDLLHGGDKTMTAAAEWTALYQIAIGVAQGI 837
Query 1012 AYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
YLH +HRDL N+LLD D ++ DFG+AK + +
Sbjct 838 CYLHHDCDPVIVHRDLKPSNILLDADFEARVADFGVAKLIQTDES----MSVVAGSYGYI 893
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM-TVLRLTEL 1127
APE + SD++S+GV L E++T S + + ++ + ++ T + E+
Sbjct 894 APEYAYTLQVDKKSDIYSYGVILLEIITGKRSVEPEFGEGNSIVDWVRSKLKTKEDVEEV 953
Query 1128 LER--GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
L++ G + ++ + C + RP +++ IL+ K + +V
Sbjct 954 LDKSMGRSCSLIREEMKQMLRIALLCTSRSPTDRPPMRDVLLILQEAKPKRKTVGDNVIV 1013
Query 1186 V 1186
V
Sbjct 1014 V 1014
Score = 189 bits (479), Expect = 2e-47, Method: Composition-based stats.
Identities = 73/395 (18%), Positives = 120/395 (30%), Gaps = 60/395 (15%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQ-LSFHRVDQKEI--TQLSHLGQGTRTNVY 604
RC G + G P L Q L+F D E + LG G+ VY
Sbjct 675 TRCFQKSYGNRVDGGGRNGGDIGPWKLTAFQRLNFTADDVVECLSKTDNILGMGSTGTVY 734
Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664
+ +G+ K G+ R ++ V ++
Sbjct 735 KA---EMPNGEIIAVKKLWGKNKENGKIRRRKSGV----------------LAEVDVLGN 775
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP----MAWKMVVAQQLAS 720
V H ++ + G C +++ EY+ +G LD L + +A +A
Sbjct 776 VRHRNIVRLLGCCTNRDCTMLLYEYMPNGSLDDLLHGGDKTMTAAAEWTALYQIAIGVAQ 835
Query 721 ALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER---VE 774
+ YL + +VH ++ NILL +++D GV + E
Sbjct 836 GICYLHHDCDPVIVHRDLKPSNILLD-------ADFEARVADFGVAKLIQTDESMSVVAG 888
Query 775 RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA--PLQSRSPS----------- 821
++APE + D + +G LLEI + P S
Sbjct 889 SYGYIAPEYA--YTLQVDKKSDIYSYGVILLEIITGKRSVEPEFGEGNSIVDWVRSKLKT 946
Query 822 --EKEHF----YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ E R L Q+ + C + PT RP R +L L +P
Sbjct 947 KEDVEEVLDKSMGRSCSLIREEMKQMLRIALLCTSRSPTDRPPMRDVLLILQEAKPKRKT 1006
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910
V +D + D+ G
Sbjct 1007 VGDNVIVVGDVNDVNFEDVCSVDVGHDVKCQRIGV 1041
>sp|Q9C660|PEK10_ARATH Proline-rich receptor-like protein kinase
PERK10 OS=Arabidopsis thaliana OX=3702 GN=PERK10 PE=1 SV=2
Length=762
Score = 231 bits (590), Expect = 2e-62, Method: Composition-based stats.
Identities = 84/391 (21%), Positives = 146/391 (37%), Gaps = 29/391 (7%)
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS---CPQLATLTSQCLTYEPTQ 855
G L+ + G + ++ + +P P P+ + + + P
Sbjct 334 SIGVALVLLTLIGVVVCCLKKRKKRLSTIGGGYVMPTPMESSSPRSDSALLKTQSSAPLV 393
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915
+ + + + + V LGEG FG+V
Sbjct 394 GNRSS-----NRTYLSQSEPGGFGQSRELFSYEELVIATNGFSDENLLGEGGFGRVYKGV 448
Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
+VAVK LK G R +K E+D + ++H +++ G C + +
Sbjct 449 L-----PDERVVAVKQLKIGGGQGDRE-FKAEVDTISRVHHRNLLSMVGYCISENRR--L 500
Query 976 LVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNV 1029
L+ +YVP +L +L + A + A G+AYLH IHRD+ + N+
Sbjct 501 LIYDYVPNNNLYFHLHAAGTPGLDWATRVKIAAGAARGLAYLHEDCHPRIIHRDIKSSNI 560
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
LL+N+ + DFGLAK + + + R + APE K SDV+SFGV
Sbjct 561 LLENNFHALVSDFGLAKLALDCNTHITTR--VMGTFGYMAPEYASSGKLTEKSDVFSFGV 618
Query 1090 TLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP-CEVYHL 1147
L EL+T S P L+ A+ ++ TE E++ +
Sbjct 619 VLLELITGRKPVDASQPLGDESLVEWARPLLSNATETEEFTALADPKLGRNYVGVEMFRM 678
Query 1148 MK---NCWETEASFRPTFENLIPILKTVHEK 1175
++ C A+ RP ++ ++ E+
Sbjct 679 IEAAAACIRHSATKRPRMSQIVRAFDSLAEE 709
Score = 219 bits (559), Expect = 2e-58, Method: Composition-based stats.
Identities = 64/346 (18%), Positives = 113/346 (33%), Gaps = 59/346 (17%)
Query 499 SLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGET 558
L+ RK + G +V+ ++ R+ + +
Sbjct 351 CLKKRKKRLSTIGGGYVMP-------------TPMESSSPRSDSALLKTQSSAPLVGNRS 397
Query 559 SNLIIMRGARASPRTLNLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616
SN + + + S+ + + + LG+G VY+G L
Sbjct 398 SNRTYLSQSEPGGFGQSRELFSYEELVIATNGFSDENLLGEGGFGRVYKGVL-------- 449
Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676
E V +K L F +S+V H +L + G
Sbjct 450 -----------------PDERVVAVKQLKIGGGQGDREFKAEVDTISRVHHRNLLSMVGY 492
Query 677 CVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENK---NLVH 732
C+ +++ +YV + L L + A ++ +A A L+YL ++H
Sbjct 493 CISENRRLLIYDYVPNNNLYFHLHAAGTPGLDWATRVKIAAGAARGLAYLHEDCHPRIIH 552
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGG 787
++ NILL A +SD G+ AL + ++APE G
Sbjct 553 RDIKSSNILLENNFHAL-------VSDFGLAKLALDCNTHITTRVMGTFGYMAPEYASSG 605
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833
L+ D + FG LLE+ G P+ + P E + L
Sbjct 606 --KLTEKSDVFSFGVVLLELI-TGRKPVDASQPLGDESLVEWARPL 648
>sp|O88506|STK39_RAT STE20/SPS1-related proline-alanine-rich protein
kinase OS=Rattus norvegicus OX=10116 GN=Stk39 PE=1 SV=2
Length=553
Score = 227 bits (578), Expect = 2e-62, Method: Composition-based stats.
Identities = 71/290 (24%), Positives = 118/290 (41%), Gaps = 24/290 (8%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ + +G G V P E VA+K + + +EI
Sbjct 65 WPICRDAYELQEVIGSGATAVVQAALCKPRQ----ERVAIKRINLEKCQTSMDELLKEIQ 120
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---------RHSIGLAQL 1000
+ H +++ Y + E L LVM+ + GS+ D + + A +
Sbjct 121 AMSQCSHPNVVTYYTSFVVKDE--LWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAII 178
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--VR 1058
+++ EG+ YLH IHRDL A N+LL D V+I DFG++ + G + R VR
Sbjct 179 ATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVR 238
Query 1059 EDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
+ W APE +++ + + +D+WSFG+T EL T P + ++ +
Sbjct 239 KTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTL--- 295
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
Q L +E E + K L+ C + + S RPT L+
Sbjct 296 QNDPPTLETGVEDKEMM---KKYGKSFRKLLSLCLQKDPSKRPTAAELLK 342
Score = 173 bits (438), Expect = 2e-44, Method: Composition-based stats.
Identities = 50/264 (19%), Positives = 97/264 (37%), Gaps = 37/264 (14%)
Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+ ++ RV +K ++ ++ + MSQ SH ++ + V E +V + +
Sbjct 92 KPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLS 151
Query 692 HGPLDVWLR-------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
G + ++ + G + A + +++ L YL +H ++ NILL
Sbjct 152 GGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGE 211
Query 745 LGLAEGTSPFIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAM 795
G ++++D GV + R+ V W+APE +
Sbjct 212 DG-------SVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKA 263
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-----------HRLPEPSCPQLATL 844
D W FG T +E+ G AP P + + + + L
Sbjct 264 DMWSFGITAIELA-TGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKL 322
Query 845 TSQCLTYEPTQRPSFRTILRDLTR 868
S CL +P++RP+ +L+
Sbjct 323 LSLCLQKDPSKRPTAAELLKCKFF 346
>sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo
sapiens OX=9606 GN=MARK2 PE=1 SV=2
Length=788
Score = 232 bits (592), Expect = 2e-62, Method: Composition-based stats.
Identities = 84/326 (26%), Positives = 129/326 (40%), Gaps = 29/326 (9%)
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
S T PT + + +S S H + ++ +G
Sbjct 1 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIG 60
Query 905 EGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963
+G+F KV L + TG+ VAVK + K +E+ I++ L H +I+K
Sbjct 61 KGNFAKVKL----ARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLF 116
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHR 1022
E EK+L LVMEY G + DYL H + + +QI + Y H + +HR
Sbjct 117 EVIE--TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHR 174
Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YA 1081
DL A N+LLD D +KI DFG + G++ + + APE + K+
Sbjct 175 DLKAENLLLDADMNIKIADFGFSNEFTFGNKL----DTFCGSPPYAAPELFQGKKYDGPE 230
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
DVWS GV LY L++ + L E + RG + P
Sbjct 231 VDVWSLGVILYTLVSGSLPFD---------------GQNLKELRERVLRG-KYRIPFYMS 274
Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167
+ +L+K S R T E ++
Sbjct 275 TDCENLLKKFLILNPSKRGTLEQIMK 300
Score = 192 bits (488), Expect = 2e-49, Method: Composition-based stats.
Identities = 61/355 (17%), Positives = 113/355 (32%), Gaps = 49/355 (14%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
+P SN+I R + S + + L +G+G V R + G
Sbjct 27 KPSSKSNMIRGRNSATS---------ADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGK 77
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLA 671
V +K++D + + + + +M ++H ++
Sbjct 78 ------------------------EVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIV 113
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
+ V +V EY G + +L G + +Q+ SA+ Y K +V
Sbjct 114 KLFEVIETEKTLYLVMEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYCHQKFIV 172
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGA 788
H ++ N+LL IK++D G + P+ APE G
Sbjct 173 HRDLKAENLLLD-------ADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKK 225
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQ 847
+D W G L + G P ++ E R +R+P L +
Sbjct 226 YD-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 283
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902
L P++R + I++D H ++ P + +
Sbjct 284 FLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYT 338
>sp|O49445|LRK72_ARATH Probable L-type lectin-domain containing
receptor kinase VII.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK72
PE=3 SV=2
Length=681
Score = 230 bits (586), Expect = 2e-62, Method: Composition-based stats.
Identities = 74/322 (23%), Positives = 123/322 (38%), Gaps = 18/322 (6%)
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917
F + R RL+ P + + +G G KV +
Sbjct 310 CFYVVRRRRQRLEGDVEDWETEYWPHRVQYKDVLEATKGFSDENMIGYGGNSKVYRGVLE 369
Query 918 PTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
G+ VAVK + S + E+ L L H++I+ KG +G +SL
Sbjct 370 ------GKEVAVKRIMMSPRESVGATSEFLAEVSSLGRLRHKNIVGLKG-WSKKGGESLI 422
Query 976 LVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVL 1030
L+ EY+ GS+ + + + + + + GM YLH +HRD+ + NVL
Sbjct 423 LIYEYMENGSVDKRIFDCNEMLNWEERMRVIRDLASGMLYLHEGWETKVLHRDIKSSNVL 482
Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
LD D ++GDFGLAK E + APE +K + +DV+SFGV
Sbjct 483 LDKDMNARVGDFGLAKLQNTSKEMVST-THVVGTAGYMAPELVKTGRASAQTDVYSFGVF 541
Query 1091 LYELLTHCDSSQSPPTKFLELI-GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149
+ E++ + +E I G+ + V L E ++ + +
Sbjct 542 VLEVVCGRRPIEEGREGIVEWIWGLMEKDKVVDGLDERIKANGVFVVEE--VEMALRIGL 599
Query 1150 NCWETEASFRPTFENLIPILKT 1171
C + RP ++ IL+
Sbjct 600 LCVHPDPRVRPKMRQVVQILEQ 621
Score = 185 bits (470), Expect = 1e-47, Method: Composition-based stats.
Identities = 57/305 (19%), Positives = 111/305 (36%), Gaps = 61/305 (20%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
K + + +G G + VY G L G+E+ V ++
Sbjct 345 ATKGFSDENMIGYGGNSKVYRGVLE------------------------GKEVAVKRIMM 380
Query 645 DPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPE-NIMVTEYVEHGPLDVWLRRE 702
P A F S + ++ H ++ + G +G E I++ EY+E+G +D +
Sbjct 381 SPRESVGATSEFLAEVSSLGRLRHKNIVGLKGWSKKGGESLILIYEYMENGSVDKRIFDC 440
Query 703 RGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ +M V + LAS + YL ++H ++ N+LL + ++ D
Sbjct 441 NEMLNWEERMRVIRDLASGMLYLHEGWETKVLHRDIKSSNVLLDK-------DMNARVGD 493
Query 760 PGVG------LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ +S V ++APE + G S D + FG +LE+ G
Sbjct 494 FGLAKLQNTSKEMVSTTHVVGTAGYMAPELVKTGRA--SAQTDVYSFGVFVLEVVC-GRR 550
Query 814 PLQSRSPSEKEHFY--QRQHRLPEPSCPQLA--------------TLTSQCLTYEPTQRP 857
P++ E + + ++ + ++ + C+ +P RP
Sbjct 551 PIEEGREGIVEWIWGLMEKDKVVDGLDERIKANGVFVVEEVEMALRIGLLCVHPDPRVRP 610
Query 858 SFRTI 862
R +
Sbjct 611 KMRQV 615
>sp|Q8VHF0|MARK3_RAT MAP/microtubule affinity-regulating kinase
3 OS=Rattus norvegicus OX=10116 GN=Mark3 PE=1 SV=1
Length=797
Score = 232 bits (592), Expect = 2e-62, Method: Composition-based stats.
Identities = 76/280 (27%), Positives = 118/280 (42%), Gaps = 29/280 (10%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEID 949
H + ++ +G+G+F KV L + TG VA+K + K P +E+
Sbjct 50 QPHIGNYRLLKTIGKGNFAKVKL----ARHILTGREVAIKIIDKTQLNPTSLQKLFREVR 105
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQIC 1008
I++ L H +I+K E EK+L L+MEY G + DYL H + + +QI
Sbjct 106 IMKILNHPNIVKLFEVIE--TEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIV 163
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+ Y H + +HRDL A N+LLD D +KI DFG + G + + +
Sbjct 164 SAVQYCHQKRIVHRDLKAENLLLDADMNIKITDFGFSNEFTVGSKL----DTFCGSPPYA 219
Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + K+ DVWS GV LY L++ + L E
Sbjct 220 APELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD---------------GQNLKELRER 264
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ RG + P + +L+K R T E ++
Sbjct 265 VLRG-KYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMK 303
Score = 189 bits (481), Expect = 2e-48, Method: Composition-based stats.
Identities = 57/319 (18%), Positives = 106/319 (33%), Gaps = 41/319 (13%)
Query 556 GETSNLIIMRGARASPRTLN-LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
G+ + R R+ R N ++ + + L +G+G V R + G
Sbjct 22 GDGRQEVTSRTGRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGR- 80
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAF 672
V +K++D + + + +M ++H ++
Sbjct 81 -----------------------EVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 117
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVH 732
+ V ++ EY G + +L G + +Q+ SA+ Y K +VH
Sbjct 118 LFEVIETEKTLYLIMEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYCHQKRIVH 176
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGAN 789
++ N+LL IK++D G + P+ APE G
Sbjct 177 RDLKAENLLLD-------ADMNIKITDFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKY 229
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQC 848
+D W G L + G P ++ E R +R+P L +
Sbjct 230 D-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRF 287
Query 849 LTYEPTQRPSFRTILRDLT 867
L P +R + I++D
Sbjct 288 LVLNPVKRGTLEQIMKDRW 306
>sp|Q9Z138|ROR2_MOUSE Tyrosine-protein kinase transmembrane receptor
ROR2 OS=Mus musculus OX=10090 GN=Ror2 PE=1 SV=2
Length=944
Score = 234 bits (598), Expect = 2e-62, Method: Composition-based stats.
Identities = 90/410 (22%), Positives = 152/410 (37%), Gaps = 55/410 (13%)
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP 839
P C N D P R S+ Y +
Sbjct 375 PWCFTQNKNVRVELCDV---------------PPCSPRDGSKMGILYILVPSIAIPLVIA 419
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899
L L C + + + + + + + + ++
Sbjct 420 CLFFLVCMCRNKQKASASTP----QRRQLMASPSQDMEMPLISQHKQAKLKEISLSTVRF 475
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTG-EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+ +LGE FGKV G + VA+K LK R ++QE + L H +
Sbjct 476 MEELGEDRFGKVYKGHLFGPAPGEPTQAVAIKTLKDKAEGPLREEFRQEAMLRARLQHPN 535
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----------------RHSIGLAQLL 1001
I+ G ++ L ++ Y G L ++L + ++ +
Sbjct 536 IVCLLGVVTK--DQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFV 593
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
QI GM +L + H +H+DLA RNVL+ + V+I D GL + V +YY++ +
Sbjct 594 HVVAQIAAGMEFLSSHHVVHKDLATRNVLVYDKLNVRISDLGLFREVY-SADYYKLMGNS 652
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
P+ W +PE + KF SD+WS+GV L+E+ ++ +
Sbjct 653 LLPIRWMSPEAVMYGKFSIDSDIWSYGVVLWEVFSYGLQ--------------PYCGYSN 698
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ E++ + LP PD CP VY LM CW S RP F+++ L++
Sbjct 699 QDVVEMIRSRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRS 748
Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats.
Identities = 82/435 (19%), Positives = 151/435 (35%), Gaps = 77/435 (18%)
Query 475 WSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQ 534
W+ HP+ L+ + + G R P Q +G + + ++
Sbjct 340 WALQHPHSHRLSSTEFPELGGGHAYCR---NPGGQVEGPWCFTQNKNVRVELCDVPPCSP 396
Query 535 GCLLRAGDD--------------CFSLRRC-CLPQPGETSNLIIMRGARASPRT------ 573
+ G C C C + +++ R ASP
Sbjct 397 RDGSKMGILYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPL 456
Query 574 -LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
Q + + + LG+ VY+G L G+P +
Sbjct 457 ISQHKQAKLKEISLSTVRFMEELGEDRFGKVYKGHLFGPAPGEPTQ-------------- 502
Query 633 RGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
V +K L D + + F + A L +++ H ++ + GV + M+ Y
Sbjct 503 -----AVAIKTLKDKAEGPLREEFRQEAMLRARLQHPNIVCLLGVVTKDQPLSMIFSYCS 557
Query 692 HGPLDVWL---------------RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736
HG L +L R + + + V Q+A+ + +L + ++VH ++
Sbjct 558 HGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHVVAQIAAGMEFLSSHHVVHKDLA 617
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANS 790
RN+L+ +++SD G+ S + + I W++PE + G S
Sbjct 618 TRNVLV-------YDKLNVRISDLGLFREVYSADYYKLMGNSLLPIRWMSPEAVMYGKFS 670
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQC 848
+ D W +G L E+ G P S + + + LP P CP + L +C
Sbjct 671 ID--SDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRSRQVLPCPDDCPAWVYALMIEC 728
Query 849 LTYEPTQRPSFRTIL 863
P++RP F+ I
Sbjct 729 WNEFPSRRPRFKDIH 743
>sp|Q9Z1W9|STK39_MOUSE STE20/SPS1-related proline-alanine-rich
protein kinase OS=Mus musculus OX=10090 GN=Stk39 PE=1 SV=1
Length=556
Score = 227 bits (578), Expect = 2e-62, Method: Composition-based stats.
Identities = 71/290 (24%), Positives = 118/290 (41%), Gaps = 24/290 (8%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ + +G G V P E VA+K + + +EI
Sbjct 68 WPICRDAYELQEVIGSGATAVVQAALCKPRQ----ERVAIKRINLEKCQTSMDELLKEIQ 123
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---------RHSIGLAQL 1000
+ H +++ Y + E L LVM+ + GS+ D + + A +
Sbjct 124 AMSQCSHPNVVTYYTSFVVKDE--LWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAII 181
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--VR 1058
+++ EG+ YLH IHRDL A N+LL D V+I DFG++ + G + R VR
Sbjct 182 ATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVR 241
Query 1059 EDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
+ W APE +++ + + +D+WSFG+T EL T P + ++ +
Sbjct 242 KTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTL--- 298
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
Q L +E E + K L+ C + + S RPT L+
Sbjct 299 QNDPPTLETGVEDKEMM---KKYGKSFRKLLSLCLQKDPSKRPTAAELLK 345
Score = 173 bits (438), Expect = 3e-44, Method: Composition-based stats.
Identities = 50/264 (19%), Positives = 97/264 (37%), Gaps = 37/264 (14%)
Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+ ++ RV +K ++ ++ + MSQ SH ++ + V E +V + +
Sbjct 95 KPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLS 154
Query 692 HGPLDVWLR-------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
G + ++ + G + A + +++ L YL +H ++ NILL
Sbjct 155 GGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGE 214
Query 745 LGLAEGTSPFIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAM 795
G ++++D GV + R+ V W+APE +
Sbjct 215 DG-------SVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKA 266
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-----------HRLPEPSCPQLATL 844
D W FG T +E+ G AP P + + + + L
Sbjct 267 DMWSFGITAIELA-TGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKL 325
Query 845 TSQCLTYEPTQRPSFRTILRDLTR 868
S CL +P++RP+ +L+
Sbjct 326 LSLCLQKDPSKRPTAAELLKCKFF 349
>sp|Q9T020|Y4391_ARATH Probable receptor-like protein kinase At4g39110
OS=Arabidopsis thaliana OX=3702 GN=At4g39110 PE=3 SV=1
Length=878
Score = 233 bits (595), Expect = 2e-62, Method: Composition-based stats.
Identities = 74/275 (27%), Positives = 115/275 (42%), Gaps = 17/275 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + D G VAVK Q + ++ EI +L L H H++
Sbjct 532 IGVGGFGNVYIGTLD-----DGTKVAVKRGNP-QSEQGITEFQTEIQMLSKLRHRHLVSL 585
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHA--- 1016
G C++ E + LV E++ G RD+L + Q L G+ YLH
Sbjct 586 IGYCDENSE--MILVYEFMSNGPFRDHLYGKNLAPLTWKQRLEICIGSARGLHYLHTGTA 643
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
Q IHRD+ + N+LLD + K+ DFGL+K V G + V + PE +
Sbjct 644 QGIIHRDVKSTNILLDEALVAKVADFGLSKDVAFGQNH--VSTAVKGSFGYLDPEYFRRQ 701
Query 1077 KFYYASDVWSFGVTLYE-LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ SDV+SFGV L E L + P + + L A L ++++
Sbjct 702 QLTDKSDVYSFGVVLLEALCARPAINPQLPREQVNLAEWAMQWKRKGLLEKIIDPHLAGT 761
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ + + C E RPT +++ L+
Sbjct 762 INPESMKKFAEAAEKCLEDYGVDRPTMGDVLWNLE 796
Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats.
Identities = 65/319 (20%), Positives = 108/319 (34%), Gaps = 60/319 (19%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
LS + K +G G NVY G L
Sbjct 513 YFSLSELQEATKNFEASQIIGVGGFGNVYIGTLDDG------------------------ 548
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+V +K +P F ++S++ H HL + G C E I+V E++ +GP
Sbjct 549 -TKVAVKRGNPQSEQGITEFQTEIQMLSKLRHRHLVSLIGYCDENSEMILVYEFMSNGPF 607
Query 696 DVWLRRER-GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGT 751
L + + ++ + A L YL + ++H +V NILL +A
Sbjct 608 RDHLYGKNLAPLTWKQRLEICIGSARGLHYLHTGTAQGIIHRDVKSTNILLDEALVA--- 664
Query 752 SPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
K++D G+ + V +L PE L+ D + FG LLE
Sbjct 665 ----KVADFGLSKDVAFGQNHVSTAVKGSFGYLDPEYFR--RQQLTDKSDVYSFGVVLLE 718
Query 807 ICFDG-----EAPLQSRSPSEKEHFYQRQHRLPEPSCPQL------------ATLTSQCL 849
+ P + + +E ++R+ L + P L A +CL
Sbjct 719 ALCARPAINPQLPREQVNLAEWAMQWKRKGLLEKIIDPHLAGTINPESMKKFAEAAEKCL 778
Query 850 TYEPTQRPSFRTILRDLTR 868
RP+ +L +L
Sbjct 779 EDYGVDRPTMGDVLWNLEY 797
>sp|Q10LQ2|CIPKA_ORYSJ CBL-interacting protein kinase 10 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK10 PE=2 SV=1
Length=451
Score = 223 bits (569), Expect = 2e-62, Method: Composition-based stats.
Identities = 58/268 (22%), Positives = 111/268 (41%), Gaps = 26/268 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHII 960
LG+G F KV Y N + VA+K + + + ++EI ++ + H I+
Sbjct 19 LGQGSFAKV----YHGRNIKNSQSVAIKVIDKEKILKCELMDQIRREISVMNLVRHPCIV 74
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ + + + ++EYV G L + + R + + QQ+ + + H++
Sbjct 75 QLYEVMATKTK--IYFILEYVKGGELFNKVRRGRLKEEVARKYFQQLISAIDFCHSRGVY 132
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
HRDL N+LLD +R +KI DFGL+ + + +P + APE + +
Sbjct 133 HRDLKPENLLLDENRNLKISDFGLSALAECKRQDGLLHTTCGTPA-YVAPEVINRKGYDG 191
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+DVW+ GV LY LL Q V+ + + + + E P
Sbjct 192 AKADVWACGVILYVLLAGYLPFQD---------------KNVINMYKKICKAE-FKWPSW 235
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
++ L++ + + R + ++
Sbjct 236 FSSDIRKLLRRILDPNPATRISVSEIME 263
Score = 184 bits (466), Expect = 9e-49, Method: Composition-based stats.
Identities = 57/295 (19%), Positives = 98/295 (33%), Gaps = 45/295 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ K LGQG+ VY GR V +KV
Sbjct 8 ILMKRYEIGKLLGQGSFAKVYHGRNIKNSQS------------------------VAIKV 43
Query 644 LDPSHH---DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
+D ++ S+M+ V H + ++ V + + EYV+ G L +
Sbjct 44 IDKEKILKCELMDQIRREISVMNLVRHPCIVQLYEVMATKTKIYFILEYVKGGELFN--K 101
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
RG + QQL SA+ + ++ + H ++ N+LL + +K+SD
Sbjct 102 VRRGRLKEEVARKYFQQLISAIDFCHSRGVYHRDLKPENLLLDE-------NRNLKISDF 154
Query 761 GVGLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ A + ++APE + D W G L + G P
Sbjct 155 GLSALAECKRQDGLLHTTCGTPAYVAPEVINRKGYD-GAKADVWACGVILY-VLLAGYLP 212
Query 815 LQSRSPSEKE-HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
Q ++ + + + P + L + L P R S I+ D
Sbjct 213 FQDKNVINMYKKICKAEFKWPSWFSSDIRKLLRRILDPNPATRISVSEIMEDPWF 267
>sp|Q61084|M3K3_MOUSE Mitogen-activated protein kinase kinase
kinase 3 OS=Mus musculus OX=10090 GN=Map3k3 PE=1 SV=1
Length=626
Score = 228 bits (582), Expect = 2e-62, Method: Composition-based stats.
Identities = 78/279 (28%), Positives = 130/279 (47%), Gaps = 24/279 (9%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP----QHRSGWKQEID 949
++ + LG+G FG+V L + TG +A K ++ D + S + EI
Sbjct 359 PINWRRGKLLGQGAFGRVYLCY----DVDTGRELASKQVQFDPDSPETSKEVSALECEIQ 414
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQIC 1008
+L+ L HE I++Y GC D+ EK L + MEY+P GS++D L + + + + +QI
Sbjct 415 LLKNLQHERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQIL 474
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
EGM+YLH+ +HRD+ N+L D+ VK+GDFG +K + +W
Sbjct 475 EGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGIRSVTGTPYWM 534
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
+PE + + +DVWS G T+ E+LT + PP E + + ++
Sbjct 535 SPEVISGEGYGRKADVWSLGCTVVEMLT-----EKPPWAEYEAMA---------AIFKIA 580
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ P ++ + EA RP+ E L+
Sbjct 581 TQPTNPQLPSHISEHGRDFLRRIF-VEARQRPSAEELLT 618
Score = 174 bits (440), Expect = 5e-44, Method: Composition-based stats.
Identities = 62/373 (17%), Positives = 115/373 (31%), Gaps = 68/373 (18%)
Query 478 SHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCL 537
++P R ++V + R+R+ Q F L RS + G
Sbjct 274 TYPRRYHVSVHHKDYNDGRRTFPRIRR----HQGNLFTLVPSSRSLST--------NGEN 321
Query 538 LRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQ 597
+ R + ++ N + ++ ++ + + LGQ
Sbjct 322 MGVAVQYLDPRGRL--RSADSENALTVQERNVPTKSPSAPI---------NWRRGKLLGQ 370
Query 598 GTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE 657
G VY L D G+EL DP + +
Sbjct 371 GAFGRVY----------------------LCYDVDTGRELASKQVQFDPDSPETSKEVSA 408
Query 658 ---TASLMSQVSHTHLAFVHGVCVRGPENI--MVTEYVEHGPLDVWLRRERGHVPMAWKM 712
L+ + H + +G E I + EY+ G + L+ G + +
Sbjct 409 LECEIQLLKNLQHERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKA-YGALTESVTR 467
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-------VGLG 765
+Q+ +SYL + +VH ++ G NIL ++ +KL D G + +
Sbjct 468 KYTRQILEGMSYLHSNMIVHRDIKGANIL-------RDSAGNVKLGDFGASKRLQTICMS 520
Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
W++PE + G D W G T++E+ + + P
Sbjct 521 GTGIRSVTGTPYWMSPEVISG--EGYGRKADVWSLGCTVVEMLTE-KPPWAEYEAMAAIF 577
Query 826 FYQRQHRLPEPSC 838
Q P+
Sbjct 578 KIATQPTNPQLPS 590
>sp|Q6P3Q4|STK4_XENTR Serine/threonine-protein kinase 4 OS=Xenopus
tropicalis OX=8364 GN=stk4 PE=2 SV=1
Length=485
Score = 224 bits (572), Expect = 2e-62, Method: Composition-based stats.
Identities = 63/270 (23%), Positives = 113/270 (42%), Gaps = 31/270 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V Y ++ T ++VA+K + + Q +EI I++ H++K
Sbjct 35 KLGEGSYGSV----YKASHKETSQIVAIKQIPVESDLQ---EIIKEIAIMQQCDSLHVVK 87
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VME+ GS+ D L + ++ + Q +G+ YLH
Sbjct 88 YYGSYFKNTD--LWIVMEFCGGGSISDIIRLRKQTLKEDETATILQSTLKGLEYLHFMRK 145
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+++ K+ DFG+A + + R FW APE ++E +
Sbjct 146 IHRDIKAGNILLNSEGTAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP--RP 1137
+D+WS G+T E+ ++ +R ++ +P
Sbjct 203 CVADIWSLGITAIEMAEGKPP---------------YAEIHPMRAIFMIPSNPPPTFRKP 247
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + + C R + L+
Sbjct 248 ELWSKDFVDFINLCLVKNPELRSSATELLQ 277
Score = 196 bits (497), Expect = 1e-52, Method: Composition-based stats.
Identities = 57/300 (19%), Positives = 98/300 (33%), Gaps = 44/300 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
LS+ S ++ ++ L LG+G+ +VY+ +
Sbjct 17 LSEESLNKQPEEVFDVLEKLGEGSYGSVYKASHKE------------------------T 52
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K + + ++M Q H+ +G + + +V E+ G +
Sbjct 53 SQIVAIKQIPVESD--LQEIIKEIAIMQQCDSLHVVKYYGSYFKNTDLWIVMEFCGGGSI 110
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + + Q L YL +H ++ NILL G A
Sbjct 111 SDIIRLRKQTLKEDETATILQSTLKGLEYLHFMRKIHRDIKAGNILLNSEGTA------- 163
Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D GV R + W+APE + + D W G T +E+ +G
Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220
Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P P R PE + CL P R S +L+
Sbjct 221 KPPYAEIHPMRAIFMIPSNPPPTFRKPELWSKDFVDFINLCLVKNPELRSSATELLQHPF 280
>sp|Q55CA6|Y0146_DICDI Probable serine/threonine-protein kinase
DDB_G0270146 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0270146
PE=3 SV=1
Length=635
Score = 229 bits (583), Expect = 2e-62, Method: Composition-based stats.
Identities = 75/320 (23%), Positives = 132/320 (41%), Gaps = 26/320 (8%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
TY + FR+ + P + ++ +G+G F
Sbjct 30 TYNKSDTVDFRSKVIPQQSNLPPINNKTDRSHFRESMVASKKTIGAFVISDIAIGKGAFA 89
Query 910 KVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968
V + N +G+ VA+K K+ + S E DIL+ L HE+I++ G +
Sbjct 90 TV----FKGLNTLSGDFVAIKRFEKSKISNEQHSSVSTEFDILQRLNHENIVRILG--RE 143
Query 969 QGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027
+ E + + +EY+ GSL L + + + + + + +G+ YLH + IHRD+ A
Sbjct 144 ENENYIYIFLEYMENGSLSTILNNFGTFPESLICNYVENVLKGLVYLHQEGVIHRDIKAA 203
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
N+L++ K+ DFG A + + + R +W APE ++ SD+WS
Sbjct 204 NILINKAGEAKLSDFGTAGEIIKESD---KRYSVVGTPYWMAPEVIEISGHCQVSDIWSL 260
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
G T+ EL T PP L +G + + +R P PD E+ +
Sbjct 261 GCTIIELFT-----SYPPYFDLNPLGAMY----------RICQDDRPPLPDDISSELANF 305
Query 1148 MKNCWETEASFRPTFENLIP 1167
++ C+ R T + L+
Sbjct 306 LERCFCKSTEERATAKELLS 325
Score = 190 bits (483), Expect = 2e-49, Method: Composition-based stats.
Identities = 58/321 (18%), Positives = 111/321 (35%), Gaps = 43/321 (13%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIA 652
+G+G V++G + G V +K + S ++
Sbjct 83 IGKGAFATVFKGLNTLSGDF------------------------VAIKRFEKSKISNEQH 118
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
+ ++ +++H ++ + G + EY+E+G L L G P +
Sbjct 119 SSVSTEFDILQRLNHENIVRILGREENENYIYIFLEYMENGSLSTIL-NNFGTFPESLIC 177
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGALS 768
+ + L YL + ++H ++ NIL+ + G A KLSD G +
Sbjct 178 NYVENVLKGLVYLHQEGVIHRDIKAANILINKAGEA-------KLSDFGTAGEIIKESDK 230
Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
R V W+APE + + D W G T++E+ F P +P +
Sbjct 231 RYSVVGTPYWMAPEVIE--ISGHCQVSDIWSLGCTIIEL-FTSYPPYFDLNPLGAMYRIC 287
Query 829 RQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
+ R LP+ +LA +C +R + + +L + N
Sbjct 288 QDDRPPLPDDISSELANFLERCFCKSTEERATAKELLSHPWITKNRTNLINHQRNSSKQF 347
Query 887 SDPTVFHKRYLKKIRDLGEGH 907
+ P + + K + G
Sbjct 348 TSPQIIINNHQKSLLSNSSGG 368
>sp|Q8RWC9|CIPK1_ARATH CBL-interacting serine/threonine-protein
kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CIPK1 PE=1 SV=2
Length=444
Score = 223 bits (568), Expect = 2e-62, Method: Composition-based stats.
Identities = 72/264 (27%), Positives = 108/264 (41%), Gaps = 27/264 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHI 959
LGEG+FGKV + +G AVK + K+EI L+ L H HI
Sbjct 25 TLGEGNFGKVKF----AKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLKHPHI 80
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
++ + + + +VME V G L D + + QQ+ +G++Y H++
Sbjct 81 VRLHEVLASKTK--INMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKG 138
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL NVLLD +KI DFGL+ + + SP + APE L +
Sbjct 139 VFHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTCGSPN-YVAPEVLANRGY 197
Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
ASD+WS GV LY +LT C + L + + +G+ P P
Sbjct 198 DGAASDIWSCGVILYVILTGCLPFDD---------------RNLAVLYQKICKGD-PPIP 241
Query 1138 DKCPCEVYHLMKNCWETEASFRPT 1161
++K + R T
Sbjct 242 RWLSPGARTMIKRMLDPNPVTRIT 265
Score = 169 bits (429), Expect = 5e-44, Method: Composition-based stats.
Identities = 54/291 (19%), Positives = 90/291 (31%), Gaps = 44/291 (15%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ LG+G V +D +K++D S
Sbjct 19 KYELGRTLGEGNFGKV------------------------KFAKDTVSGHSFAVKIIDKS 54
Query 648 ---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ +L + + H H+ +H V + MV E V G L + G
Sbjct 55 RIADLNFSLQIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFDRI-VSNG 113
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763
+ + QQL +SY +K + H ++ N+LL G IK++D G+
Sbjct 114 KLTETDGRKMFQQLIDGISYCHSKGVFHRDLKLENVLLDAKG-------HIKITDFGLSA 166
Query 764 -----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
++APE L A D W G L + G P R
Sbjct 167 LPQHFRDDGLLHTTCGSPNYVAPEVLANRGYD-GAASDIWSCGVILY-VILTGCLPFDDR 224
Query 819 SPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ + + + +P P T+ + L P R + I
Sbjct 225 NLAVLYQKICKGDPPIPRWLSPGARTMIKRMLDPNPVTRITVVGIKASEWF 275
>sp|A2QHV0|SEPH_ASPNC Cytokinesis protein sepH OS=Aspergillus
niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) OX=425011
GN=sepH PE=3 SV=1
Length=1336
Score = 237 bits (604), Expect = 2e-62, Method: Composition-based stats.
Identities = 81/317 (26%), Positives = 125/317 (39%), Gaps = 28/317 (9%)
Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVS 912
P++ P R D + +S V + + LG+G FG V
Sbjct 15 PSKIPGTPAKTRLSRLNSSPAKQDKPKDDRVVKSSAKDVAELKDYQLGDCLGKGAFGSV- 73
Query 913 LYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
Y N TGE VAVK +K D EID+L+ L H +I+KY+G +
Sbjct 74 ---YRALNWNTGETVAVKQIKLVDLPKSELRVIMLEIDLLKNLDHPNIVKYQGFV--KSA 128
Query 972 KSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030
++L +++EY GSL + L+ Q+ G+ YLH Q IHRD+ N+L
Sbjct 129 ETLNIILEYCENGSLHSIAKNFGRFPENLVGLYMSQVLHGLLYLHEQGVIHRDIKGANIL 188
Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
+ LVK+ DFG+A +W APE ++ ASD+WS G T
Sbjct 189 TTKEGLVKLADFGVA-----SRTTGLSESSVVGTPYWMAPEVIELSGATTASDIWSLGCT 243
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
+ ELL + Q + R+ + P P V +
Sbjct 244 VIELLEGKPPYYN-----------LQPMPALFRIV----NDDHPPLPQGASPAVKDFLMQ 288
Query 1151 CWETEASFRPTFENLIP 1167
C++ + + R + L+
Sbjct 289 CFQKDPNLRVSARKLLK 305
Score = 208 bits (530), Expect = 2e-53, Method: Composition-based stats.
Identities = 68/328 (21%), Positives = 114/328 (35%), Gaps = 42/328 (13%)
Query 550 CCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ-KEITQLSHLGQGTRTNVYEGRL 608
P S L + P+ + + S V + K+ LG+G +VY
Sbjct 19 PGTPAKTRLSRLNSSPAKQDKPKDDRVVKSSAKDVAELKDYQLGDCLGKGAFGSVYRALN 78
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH--HDIALAFYETASLMSQVS 666
G V +K + L+ +
Sbjct 79 WNTGE------------------------TVAVKQIKLVDLPKSELRVIMLEIDLLKNLD 114
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726
H ++ G ++ EY E+G L + + G P + Q+ L YL
Sbjct 115 HPNIVKYQGFVKSAETLNIILEYCENGSLHS-IAKNFGRFPENLVGLYMSQVLHGLLYLH 173
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIPWLAPECL 784
+ ++H ++ G NIL + GL +KL+D GV LS V W+APE +
Sbjct 174 EQGVIHRDIKGANILTTKEGL-------VKLADFGVASRTTGLSESSVVGTPYWMAPEVI 226
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH--FYQRQHRLPEPSCPQLA 842
+ +TA D W G T++E+ +G+ P + P LP+ + P +
Sbjct 227 E--LSGATTASDIWSLGCTVIELL-EGKPPYYNLQPMPALFRIVNDDHPPLPQGASPAVK 283
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
QC +P R S R +L+ +
Sbjct 284 DFLMQCFQKDPNLRVSARKLLKHPWIVN 311
>sp|Q0CL79|SEPH_ASPTN Cytokinesis protein sepH OS=Aspergillus
terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=sepH PE=3
SV=2
Length=1342
Score = 237 bits (604), Expect = 2e-62, Method: Composition-based stats.
Identities = 76/266 (29%), Positives = 116/266 (44%), Gaps = 29/266 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V Y N TGE VAVK +K P+ S + EID+L+ L H +I+KY
Sbjct 67 LGKGAFGSV----YRALNWNTGETVAVKQIKLADLPK--SELRLEIDLLKNLDHPNIVKY 120
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
+G + ++L +++EY GSL + L+ Q+ G+ YLH Q IH
Sbjct 121 QGFV--KSAETLNIILEYCENGSLHSIAKNFGRFPENLVGLYMSQVLHGLLYLHEQGVIH 178
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RD+ N+L + LVK+ DFG+A +W APE ++ A
Sbjct 179 RDIKGANILTTKEGLVKLADFGVA-----SRTTGLSESSVVGTPYWMAPEVIELSGATTA 233
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
SD+WS G T+ ELL + Q + R+ + P P
Sbjct 234 SDIWSLGCTVIELLEGKPPYYN-----------MQPMPALFRIV----NDDHPPLPQGAS 278
Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167
V + C++ + + R + L+
Sbjct 279 PAVKDFLMQCFQKDPNLRVSARKLLK 304
Score = 210 bits (534), Expect = 6e-54, Method: Composition-based stats.
Identities = 62/288 (22%), Positives = 104/288 (36%), Gaps = 40/288 (14%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
K+ LG+G +VY G V +K +
Sbjct 59 KDYQLGDCLGKGAFGSVYRALNWNTGE------------------------TVAVKQIKL 94
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
+ L+ + H ++ G ++ EY E+G L + + G
Sbjct 95 ADL-PKSELRLEIDLLKNLDHPNIVKYQGFVKSAETLNIILEYCENGSLHS-IAKNFGRF 152
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--L 764
P + Q+ L YL + ++H ++ G NIL + GL +KL+D GV
Sbjct 153 PENLVGLYMSQVLHGLLYLHEQGVIHRDIKGANILTTKEGL-------VKLADFGVASRT 205
Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
LS V W+APE + + +TA D W G T++E+ +G+ P + P
Sbjct 206 TGLSESSVVGTPYWMAPEVIE--LSGATTASDIWSLGCTVIELL-EGKPPYYNMQPMPAL 262
Query 825 H--FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
LP+ + P + QC +P R S R +L+ +
Sbjct 263 FRIVNDDHPPLPQGASPAVKDFLMQCFQKDPNLRVSARKLLKHPWIVN 310
>sp|Q93Z30|BHP_ARATH Serine/threonine-protein kinase 12 OS=Arabidopsis
thaliana OX=3702 GN=BHP PE=1 SV=1
Length=459
Score = 223 bits (569), Expect = 2e-62, Method: Composition-based stats.
Identities = 66/321 (21%), Positives = 125/321 (39%), Gaps = 31/321 (10%)
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917
+ I H +A + + + +++ +G + + +
Sbjct 121 NIDVIKILEIHGAKHPMAPMHVKTAREVPEYEINPSELDFTQSKEITKGTY---CMAMWR 177
Query 918 PTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
G VAVK L + + E+ +L+ L H +I+++ G +
Sbjct 178 ------GIQVAVKKLDDEVLSDDDQVRKFHDELALLQRLRHPNIVQFLGAVTQSN--PMM 229
Query 976 LVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLL 1031
+V EY+P G LR+ L R + A + +A I GM+YLH IHRDL N+L
Sbjct 230 IVTEYLPRGDLRELLKRKGQLKPATAVRYALDIARGMSYLHEIKGDPIIHRDLEPSNILR 289
Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091
D+ +K+ DFG++K V + +D + APE ++ +DV+SF + +
Sbjct 290 DDSGHLKVADFGVSKLVTVKEDKPFTCQDI--SCRYIAPEVFTSEEYDTKADVFSFALIV 347
Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
E++ + + ++ P + L++ C
Sbjct 348 QEMIEGRMPFAEKEDSEASEAYAGKHRPLFKAPSK------------NYPHGLKTLIEEC 395
Query 1152 WETEASFRPTFENLIPILKTV 1172
W + + RPTF +I L+++
Sbjct 396 WHEKPAKRPTFREIIKRLESI 416
Score = 205 bits (521), Expect = 6e-56, Method: Composition-based stats.
Identities = 83/399 (21%), Positives = 148/399 (37%), Gaps = 36/399 (9%)
Query 526 VRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVD 585
++EL + R DD +L + L++ R A P+ S +
Sbjct 59 IKELIDSGIDANYRDIDDRTALHVAACQGLKDVVELLLDRKAEVDPKDRWGSTPFADAIF 118
Query 586 QKEITQLSHLG-QGTRT-----NVYEGRLRVEGSGDPEEGKMDDEDPLVPGR---DRGQE 636
K I + L G + +V R E +P E + G +
Sbjct 119 YKNIDVIKILEIHGAKHPMAPMHVKTAREVPEYEINPSELDFTQSKEITKGTYCMAMWRG 178
Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
++V +K LD S D F++ +L+ ++ H ++ G + ++VTEY+ G
Sbjct 179 IQVAVKKLDDEVLSDDDQVRKFHDELALLQRLRHPNIVQFLGAVTQSNPMMIVTEYLPRG 238
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEG 750
L L+R +G + A + A +A +SYL ++H ++ NIL
Sbjct 239 DLRELLKR-KGQLKPATAVRYALDIARGMSYLHEIKGDPIIHRDLEPSNIL-------RD 290
Query 751 TSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLL 805
S +K++D GV +E++ ++APE + T D + F +
Sbjct 291 DSGHLKVADFGVSKLVTVKEDKPFTCQDISCRYIAPEVFT--SEEYDTKADVFSFALIVQ 348
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHR-----LPEPSCPQLATLTSQCLTYEPTQRPSFR 860
E+ +G P + SE Y +HR + L TL +C +P +RP+FR
Sbjct 349 EMI-EGRMPFAEKEDSEASEAYAGKHRPLFKAPSKNYPHGLKTLIEECWHEKPAKRPTFR 407
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899
I++ L + H K++
Sbjct 408 EIIKRLESILHHMGHKRQWRMRPLTCFQNFEHKKKHNWD 446
>sp|B0XR80|SAKA_ASPFC Mitogen-activated protein kinase sakA OS=Aspergillus
fumigatus (strain CBS 144.89 / FGSC A1163 / CEA10)
OX=451804 GN=sakA PE=3 SV=1
Length=366
Score = 220 bits (561), Expect = 2e-62, Method: Composition-based stats.
Identities = 68/283 (24%), Positives = 109/283 (39%), Gaps = 29/283 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + TG+ VAVK + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SARDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L + ER P + E L++ + R +
Sbjct 252 SLPKRERQPLANKFKNADPEAVDLLERMLVFDPKKRIRAGEAL 294
Score = 134 bits (336), Expect = 1e-32, Method: Composition-based stats.
Identities = 36/231 (16%), Positives = 74/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + RD+ V +K ++ P ++ Y
Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSARDQLTGQPVAVKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q4WSF6|HOG1_ASPFU Mitogen-activated protein kinase sakA OS=Aspergillus
fumigatus (strain ATCC MYA-4609 / CBS 101355 /
FGSC A1100 / Af293) OX=330879 GN=sakA PE=1 SV=1
Length=366
Score = 220 bits (561), Expect = 2e-62, Method: Composition-based stats.
Identities = 68/283 (24%), Positives = 109/283 (39%), Gaps = 29/283 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + TG+ VAVK + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SARDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L + ER P + E L++ + R +
Sbjct 252 SLPKRERQPLANKFKNADPEAVDLLERMLVFDPKKRIRAGEAL 294
Score = 134 bits (336), Expect = 1e-32, Method: Composition-based stats.
Identities = 36/231 (16%), Positives = 74/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + RD+ V +K ++ P ++ Y
Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSARDQLTGQPVAVKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q9LT96|Y5977_ARATH Probable leucine-rich repeat receptor-like
protein kinase At5g49770 OS=Arabidopsis thaliana OX=3702
GN=At5g49770 PE=1 SV=1
Length=946
Score = 234 bits (597), Expect = 2e-62, Method: Composition-based stats.
Identities = 75/261 (29%), Positives = 117/261 (45%), Gaps = 19/261 (7%)
Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982
G+++A+K Q +K EI++L ++H++++K G C DQ E+ LV EY+P
Sbjct 655 NGQVIAIKR-AQQGSMQGAFEFKTEIELLSRVHHKNVVKLLGFCFDQKEQ--MLVYEYIP 711
Query 983 LGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRL 1036
GSLRD L + + L A +G+AYLH IHRD+ + N+LLD
Sbjct 712 NGSLRDGLSGKNGVKLDWTRRLKIALGSGKGLAYLHELADPPIIHRDVKSNNILLDEHLT 771
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
K+ DFGL+K V + + + V + + PE + SDV+ FGV + ELLT
Sbjct 772 AKVADFGLSKLVGDPEKAH-VTTQVKGTMGYLDPEYYMTNQLTEKSDVYGFGVVMLELLT 830
Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE-----RGERLPRPDKCPCEVYHLMKNC 1151
E+ + L ELL+ L +K + C
Sbjct 831 GKSPIDRGSYVVKEVKKKMDKSRNLYDLQELLDTTIIQNSGNLKGFEKY----VDVALQC 886
Query 1152 WETEASFRPTFENLIPILKTV 1172
E E RPT ++ L+++
Sbjct 887 VEPEGVNRPTMSEVVQELESI 907
Score = 197 bits (501), Expect = 2e-50, Method: Composition-based stats.
Identities = 61/333 (18%), Positives = 116/333 (35%), Gaps = 40/333 (12%)
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
+ RA T ++ + + E+ +G T +E + +
Sbjct 587 QKKRAQRATDQMNPFAKWDAGKNEMDAPQLMGTKAFT--FEELSKCTNNFSDANDVGGGG 644
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
V + +K A F L+S+V H ++ + G C E +
Sbjct 645 YGQVYKGTLPNGQVIAIKRAQQGSMQGAFEFKTEIELLSRVHHKNVVKLLGFCFDQKEQM 704
Query 685 MVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNI 740
+V EY+ +G L L + G + ++ +A L+YL ++H +V NI
Sbjct 705 LVYEYIPNGSLRDGLSGKNGVKLDWTRRLKIALGSGKGLAYLHELADPPIIHRDVKSNNI 764
Query 741 LLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTA 794
LL K++D G+ A + + +L PE N L+
Sbjct 765 LLDE-------HLTAKVADFGLSKLVGDPEKAHVTTQVKGTMGYLDPEYYMT--NQLTEK 815
Query 795 MDKWGFGATLLEICFDGEAPLQSRS--PSEKEHFYQRQHRLPEPS--------------- 837
D +GFG +LE+ G++P+ S E + + L +
Sbjct 816 SDVYGFGVVMLELL-TGKSPIDRGSYVVKEVKKKMDKSRNLYDLQELLDTTIIQNSGNLK 874
Query 838 -CPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + QC+ E RP+ ++++L +
Sbjct 875 GFEKYVDVALQCVEPEGVNRPTMSEVVQELESI 907
>sp|Q8BRK8|AAPK2_MOUSE 5'-AMP-activated protein kinase catalytic
subunit alpha-2 OS=Mus musculus OX=10090 GN=Prkaa2 PE=1 SV=3
Length=552
Score = 226 bits (576), Expect = 2e-62, Method: Composition-based stats.
Identities = 78/274 (28%), Positives = 106/274 (39%), Gaps = 30/274 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953
+ LG G FGKV + + TG VAVK L K+EI L+
Sbjct 15 HYVLGDTLGVGTFGKVKIGEHQ----LTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012
H HIIK + +VMEYV G L DY+ +H + + QQI +
Sbjct 71 FRHPHIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVD 128
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE
Sbjct 129 YCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 184
Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + D+WS GV LY LL L RG
Sbjct 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLF----------------KKIRG 228
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
PD V L+ + + + R T +++
Sbjct 229 GVFYIPDYLNRSVATLLMHMLQVDPLKRATIKDI 262
Score = 179 bits (455), Expect = 2e-46, Method: Composition-based stats.
Identities = 57/298 (19%), Positives = 96/298 (32%), Gaps = 39/298 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
Q RV LG GT V G ++ G
Sbjct 4 KQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGH----------------------- 40
Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+V +K+L+ D+ + H H+ ++ V + MV EYV G
Sbjct 41 -KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGG 99
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L ++ + G V + QQ+ SA+ Y +VH ++ N+LL
Sbjct 100 ELFDYICKH-GRVEEVEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLD-------AQM 151
Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ E + APE + G + +D W G L +
Sbjct 152 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSCGVILYALLCG 210
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
P+ + +P+ +ATL L +P +R + + I
Sbjct 211 TLPFDDEHVPTLFKKIRGGVFYIPDYLNRSVATLLMHMLQVDPLKRATIKDIREHEWF 268
>sp|G4N7X0|MST11_PYRO7 Mitogen-activated protein kinase kinae
kinase MST11 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617
/ FGSC 8958) OX=242507 GN=MST11 PE=1 SV=1
Length=915
Score = 234 bits (596), Expect = 2e-62, Method: Composition-based stats.
Identities = 81/299 (27%), Positives = 135/299 (45%), Gaps = 38/299 (13%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC----------GPQHR 941
+ K +G+G FG V L + TGE++AVK ++A
Sbjct 636 WDDSKWMKGALIGQGSFGCVYL----ALHAITGELLAVKQVEAPSPGANSQNDARKKSMI 691
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQL 1000
K+EI +LR L H +I++Y GC + L + +EYVP GS++ L + + +
Sbjct 692 EALKREISLLRDLRHPNIVQYLGC--GSSAEYLNIFLEYVPGGSVQTMLNSYGALPEPLV 749
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-----EGHEYY 1055
F +QI G++YLH + IHRD+ N+L+DN +KI DFG++K + G
Sbjct 750 RSFVRQILNGLSYLHEREIIHRDIKGANILVDNKGTIKISDFGISKKIEATNLLNGANNN 809
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
+ R VFW APE +K+ + +D+WS G + E++T T+ + I
Sbjct 810 KHRPSLQGSVFWMAPEVVKQTSYTRKADIWSLGCLVVEMMTGTHPFPD-CTQLQAIFKIG 868
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTV 1172
G+ T P+ E + +E + + RP+ ++L+ P L +
Sbjct 869 GGKAT-------------PTIPEDASTEAKAFLAQTFEMDHNKRPSADDLMLSPFLTPI 914
Score = 186 bits (473), Expect = 5e-47, Method: Composition-based stats.
Identities = 60/302 (20%), Positives = 106/302 (35%), Gaps = 39/302 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S LS D + + + +GQG+ VY + G E + + PG +
Sbjct 629 SFLSGESWDDSKWMKGALIGQGSFGCVYLALHAITG----ELLAVKQVEAPSPGANSQN- 683
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
D + A SL+ + H ++ G + EYV G +
Sbjct 684 --------DARKKSMIEALKREISLLRDLRHPNIVQYLGCGSSAEYLNIFLEYVPGGSVQ 735
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
L G +P +Q+ + LSYL + ++H ++ G NIL+ G IK
Sbjct 736 TML-NSYGALPEPLVRSFVRQILNGLSYLHEREIIHRDIKGANILVDNKG-------TIK 787
Query 757 LSDPGVGLGALS------------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+SD G+ + R + W+APE + S + D W G +
Sbjct 788 ISDFGISKKIEATNLLNGANNNKHRPSLQGSVFWMAPEVVKQ--TSYTRKADIWSLGCLV 845
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQH---RLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861
+E+ G P + + +PE + + +Q + +RPS
Sbjct 846 VEMM-TGTHPFPDCTQLQAIFKIGGGKATPTIPEDASTEAKAFLAQTFEMDHNKRPSADD 904
Query 862 IL 863
++
Sbjct 905 LM 906
>sp|Q9ZQQ7|Y2144_ARATH Putative leucine-rich repeat receptor-like
serine/threonine-protein kinase At2g14440 OS=Arabidopsis
thaliana OX=3702 GN=At2g14440 PE=3 SV=1
Length=886
Score = 233 bits (594), Expect = 2e-62, Method: Composition-based stats.
Identities = 73/378 (19%), Positives = 143/378 (38%), Gaps = 25/378 (7%)
Query 809 FDGEAPL--QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
G P Q R ++ + +H+ +A++ C+ I
Sbjct 496 LRGSVPQALQDRENNDGLKLLRGKHQPKSWLVAIVASI--SCVA---VTIIVLVLIFIFR 550
Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926
R ++ + + + LG+G FG V E
Sbjct 551 RRKSSTRKVIRPSLEMKNRRFKYSEVKEMTNNFEVVLGKGGFGVVYHGFL------NNEQ 604
Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
VAVK L ++ +K E+++L ++H +++ G C+ + L L+ E++ G+L
Sbjct 605 VAVKVLSQSSTQGYKE-FKTEVELLLRVHHVNLVSLVGYCDKGND--LALIYEFMENGNL 661
Query 987 RDYLPRHS----IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKI 1039
+++L + L A + G+ YLH +HRD+ + N+LL K+
Sbjct 662 KEHLSGKRGGPVLNWPGRLKIAIESALGIEYLHIGCKPPMVHRDVKSTNILLGLRFEAKL 721
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099
DFGL+++ G + + V + + + PE ++ SDV+SFG+ L E++T
Sbjct 722 ADFGLSRSFLVGSQTH-VSTNVAGTLGYLDPEYYQKNWLTEKSDVYSFGIVLLEIITGQP 780
Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+ K ++ A+ + + +++R + L C ++ R
Sbjct 781 VIEQSRDKSY-IVEWAKSMLANGDIESIMDRNLHQDYDTSSSWKALELAMLCINPSSTLR 839
Query 1160 PTFENLIPILKTVHEKYQ 1177
P + L E Y
Sbjct 840 PNMTRVAHELNECLEIYN 857
Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats.
Identities = 76/395 (19%), Positives = 138/395 (35%), Gaps = 63/395 (16%)
Query 508 EQQDGAFVLEGWGRSFPSVRELGAA--LQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMR 565
E DG +L G + + + A+ + F RR ++S ++R
Sbjct 508 ENNDGLKLLRGKHQPKSWLVAIVASISCVAVTIIVLVLIFIFRR------RKSSTRKVIR 561
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
+ + + + V + LG+G VY G L E
Sbjct 562 PSLE----MKNRRFKYSEVKEMTNNFEVVLGKGGFGVVYHGFLNNE-------------- 603
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
+V +KVL S F L+ +V H +L + G C +G + +
Sbjct 604 ------------QVAVKVLSQSSTQGYKEFKTEVELLLRVHHVNLVSLVGYCDKGNDLAL 651
Query 686 VTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNI 740
+ E++E+G L L +RG + W ++ +A + A + YL +VH +V NI
Sbjct 652 IYEFMENGNLKEHLSGKRGGPVLNWPGRLKIAIESALGIEYLHIGCKPPMVHRDVKSTNI 711
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTA 794
LL G KL+D G+ L + + +L PE N L+
Sbjct 712 LL-------GLRFEAKLADFGLSRSFLVGSQTHVSTNVAGTLGYLDPEYYQ--KNWLTEK 762
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854
D + FG LLEI P+ +S + + L + ++ + L +
Sbjct 763 SDVYSFGIVLLEIITG--QPVIEQSRDKSYIVEWAKSMLANG---DIESIMDRNLHQDYD 817
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
S++ + + + P + ++
Sbjct 818 TSSSWKALELAMLCINPSSTLRPNMTRVAHELNEC 852
>sp|Q5JLQ9|CIPKU_ORYSJ CBL-interacting protein kinase 30 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK30 PE=2 SV=1
Length=476
Score = 224 bits (570), Expect = 2e-62, Method: Composition-based stats.
Identities = 67/269 (25%), Positives = 106/269 (39%), Gaps = 27/269 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960
LG G F KV Y TGE VA+K + + K+E+D++R ++H H+I
Sbjct 23 LGRGTFAKV----YKAYKLATGEAVAIKVFDKEAVQRSGTVEQVKREVDVMRRVHHRHVI 78
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019
+ + + VMEY G L L R + QQ+ + + H++
Sbjct 79 RLHEVMATRS--RIYFVMEYASGGELFTRLSRSPRFPEPVARRYFQQLITAVEFCHSRGV 136
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
HRDL N+LLD +K+ DFGL+ A+ G + + APE L + +
Sbjct 137 YHRDLKPENLLLDARGDLKVTDFGLS-ALDGGLRGDGLLHTTCGTPAYVAPEVLLKRGYD 195
Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+D+WS GV L+ LL P L+ + + + E R P
Sbjct 196 GAKADIWSCGVILFVLLAG-----YLPFNETNLVILYRN---------ITESNYR--CPP 239
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIP 1167
E L+ + R T ++
Sbjct 240 WFSVEARKLLARLLDPNPKTRITISKIMD 268
Score = 181 bits (458), Expect = 2e-47, Method: Composition-based stats.
Identities = 54/298 (18%), Positives = 88/298 (30%), Gaps = 42/298 (14%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
LG+GT VY+ G V +KV D
Sbjct 18 KLGRLLGRGTFAKVYKAYKLATGE------------------------AVAIKVFDKEAV 53
Query 650 D---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
+M +V H H+ +H V V EY G L L R
Sbjct 54 QRSGTVEQVKREVDVMRRVHHRHVIRLHEVMATRSRIYFVMEYASGGELFTRLSRS-PRF 112
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--- 763
P QQL +A+ + ++ + H ++ N+LL G +K++D G+
Sbjct 113 PEPVARRYFQQLITAVEFCHSRGVYHRDLKPENLLLDARGD-------LKVTDFGLSALD 165
Query 764 ---LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
G ++APE L D W G L + ++
Sbjct 166 GGLRGDGLLHTTCGTPAYVAPEVLLKRGYD-GAKADIWSCGVILFVLLAGYLPFNETNLV 224
Query 821 SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + +R P + L ++ L P R + I+ Q +
Sbjct 225 ILYRNITESNYRCPPWFSVEARKLLARLLDPNPKTRITISKIMDRPWFQQATCPLGDM 282
>sp|Q9FIF1|LRK21_ARATH Probable L-type lectin-domain containing
receptor kinase II.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK21
PE=2 SV=1
Length=674
Score = 229 bits (584), Expect = 3e-62, Method: Composition-based stats.
Identities = 72/299 (24%), Positives = 126/299 (42%), Gaps = 19/299 (6%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
+P + + ++ + LG G FGKV +G +AVK + D Q
Sbjct 338 YSPQRYSFRILYKATKGFRENQLLGAGGFGKVYKGIL-----PSGTQIAVKRVYHDA-EQ 391
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----I 995
+ EI + L H++++ G C +GE L LV +Y+P GSL DYL + +
Sbjct 392 GMKQYVAEIASMGRLRHKNLVHLLGYCRRKGE--LLLVYDYMPNGSLDDYLFHKNKLKDL 449
Query 996 GLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
+Q + + + + YLH + +HRD+ A N+LLD D K+GDFGLA+ G
Sbjct 450 TWSQRVNIIKGVASALLYLHEEWEQVVLHRDIKASNILLDADLNGKLGDFGLARFHDRGV 509
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLEL 1111
R + + APE +DV++FG + E++ P + + L
Sbjct 510 NLEATR--VVGTIGYMAPELTAMGVTTTCTDVYAFGAFILEVVCGRRPVDPDAPREQVIL 567
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ LT+ ++ + ++ + L C + RP+ ++ L+
Sbjct 568 VKWVASCGKRDALTDTVDSKLIDFKVEEAKL-LLKLGMLCSQINPENRPSMRQILQYLE 625
Score = 218 bits (555), Expect = 1e-58, Method: Composition-based stats.
Identities = 67/308 (22%), Positives = 112/308 (36%), Gaps = 62/308 (20%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
K + LG G VY+G L ++ +K +
Sbjct 351 ATKGFRENQLLGAGGFGKVYKGIL-------------------------PSGTQIAVKRV 385
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ + M ++ H +L + G C R E ++V +Y+ +G LD +L +
Sbjct 386 YHDAEQGMKQYVAEIASMGRLRHKNLVHLLGYCRRKGELLLVYDYMPNGSLDDYLFHKNK 445
Query 705 HVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ W ++ + + +ASAL YL + ++H ++ NILL KL D
Sbjct 446 LKDLTWSQRVNIIKGVASALLYLHEEWEQVVLHRDIKASNILLD-------ADLNGKLGD 498
Query 760 PGVGLGA-----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ L V I ++APE G +T D + FGA +LE+ G P
Sbjct 499 FGLARFHDRGVNLEATRVVGTIGYMAPELTAMGVT--TTCTDVYAFGAFILEVVC-GRRP 555
Query 815 LQSRSPSEKEHF------YQRQHRLPEPSCPQLAT-----------LTSQCLTYEPTQRP 857
+ +P E+ ++ L + +L L C P RP
Sbjct 556 VDPDAPREQVILVKWVASCGKRDALTDTVDSKLIDFKVEEAKLLLKLGMLCSQINPENRP 615
Query 858 SFRTILRD 865
S R IL+
Sbjct 616 SMRQILQY 623
>sp|A1D2C9|HOG1_NEOFI Mitogen-activated protein kinase hog1 OS=Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65
/ FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=hog1
PE=3 SV=1
Length=366
Score = 220 bits (561), Expect = 3e-62, Method: Composition-based stats.
Identities = 70/293 (24%), Positives = 112/293 (38%), Gaps = 31/293 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + TG+ VAVK + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SARDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHE 1174
L + ER P + E L++ + R + L H+
Sbjct 252 SLPKRERQPLANKFKNADPEAVDLLERMLVFDPKKRIRAGEALAHEYLTPYHD 304
Score = 134 bits (336), Expect = 2e-32, Method: Composition-based stats.
Identities = 36/231 (16%), Positives = 74/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + RD+ V +K ++ P ++ Y
Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSARDQLTGQPVAVKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q5B4Z3|SEPH_EMENI Cytokinesis protein sepH OS=Emericella nidulans
(strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194
/ M139) OX=227321 GN=sepH PE=3 SV=2
Length=1346
Score = 237 bits (604), Expect = 3e-62, Method: Composition-based stats.
Identities = 75/267 (28%), Positives = 113/267 (42%), Gaps = 28/267 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG G FG V Y N TGE VAVK +K AD EID+L+ L H +I+K
Sbjct 66 LGRGAFGSV----YRALNWNTGETVAVKQIKLADLPKSELRVIMLEIDLLKNLDHPNIVK 121
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
Y+G + ++L +++EY GSL + ++ Q+ G+ YLH Q I
Sbjct 122 YQGFV--KSAETLNIILEYCENGSLHSIAKNFGRFPETLVGVYMSQVLHGLLYLHDQGVI 179
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ N+L + LVK+ DFG+A +W APE ++
Sbjct 180 HRDIKGANILTTKEGLVKLADFGVA-----SRTTGLSESSVVGTPYWMAPEVIELSGATT 234
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
ASD+WS G T+ ELL + Q + R+ + P P
Sbjct 235 ASDIWSLGCTVIELLEGKPPYYN-----------LQPMPALFRIV----NDDHPPLPQGA 279
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIP 1167
V + C++ + + R + L+
Sbjct 280 SPAVKDFLMQCFQKDPNLRVSARKLLK 306
Score = 207 bits (528), Expect = 4e-53, Method: Composition-based stats.
Identities = 63/290 (22%), Positives = 105/290 (36%), Gaps = 41/290 (14%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
K+ LG+G +VY G V +K +
Sbjct 58 KDYQLGDCLGRGAFGSVYRALNWNTGE------------------------TVAVKQIKL 93
Query 647 SH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ L+ + H ++ G ++ EY E+G L + + G
Sbjct 94 ADLPKSELRVIMLEIDLLKNLDHPNIVKYQGFVKSAETLNIILEYCENGSLHS-IAKNFG 152
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763
P V Q+ L YL ++ ++H ++ G NIL + GL +KL+D GV
Sbjct 153 RFPETLVGVYMSQVLHGLLYLHDQGVIHRDIKGANILTTKEGL-------VKLADFGVAS 205
Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
LS V W+APE + + +TA D W G T++E+ +G+ P + P
Sbjct 206 RTTGLSESSVVGTPYWMAPEVIE--LSGATTASDIWSLGCTVIELL-EGKPPYYNLQPMP 262
Query 823 KEH--FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
LP+ + P + QC +P R S R +L+ +
Sbjct 263 ALFRIVNDDHPPLPQGASPAVKDFLMQCFQKDPNLRVSARKLLKHPWIVN 312
>sp|Q9LP51|CIPKI_ARATH CBL-interacting serine/threonine-protein
kinase 18 OS=Arabidopsis thaliana OX=3702 GN=CIPK18 PE=1 SV=1
Length=520
Score = 225 bits (573), Expect = 3e-62, Method: Composition-based stats.
Identities = 69/313 (22%), Positives = 125/313 (40%), Gaps = 26/313 (8%)
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917
+L + + ++ +P SP S + + LG G F KV L
Sbjct 35 YMADLLGRIGIMDTDKDGNISPQSPRSPRSPRNNILMGKYELGKLLGHGTFAKVYL---- 90
Query 918 PTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
N +G+ VA+K + + + + K+EI ILR + H +I+ + + +
Sbjct 91 AQNIKSGDKVAIKVIDKEKIMKSGLVAHIKREISILRRVRHPYIVHLFEVMATKSK--IY 148
Query 976 LVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035
VMEYV G L + + + + + QQ+ +++ H + HRDL N+LLDN
Sbjct 149 FVMEYVGGGELFNTVAKGRLPEETARRYFQQLISSVSFCHGRGVYHRDLKPENLLLDNKG 208
Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYEL 1094
+K+ DFGL+ + + +P + APE L + +DVWS GV L+ L
Sbjct 209 NLKVSDFGLSAVAEQLRQDGLCHTFCGTPA-YIAPEVLTRKGYDAAKADVWSCGVILFVL 267
Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154
+ ++ + + + +GE P ++ L+ +T
Sbjct 268 MAGHIPFYD---------------KNIMVMYKKIYKGE-FRCPRWFSSDLVRLLTRLLDT 311
Query 1155 EASFRPTFENLIP 1167
R T ++
Sbjct 312 NPDTRITIPEIMK 324
Score = 178 bits (452), Expect = 2e-46, Method: Composition-based stats.
Identities = 57/332 (17%), Positives = 104/332 (31%), Gaps = 45/332 (14%)
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
+ SP++ + + + + LG GT VY + G
Sbjct 50 KDGNISPQSPRSPRSPRNNILMGKYELGKLLGHGTFAKVYLAQNIKSGD----------- 98
Query 625 DPLVPGRDRGQELRVVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
+V +KV+D + S++ +V H ++ + V
Sbjct 99 -------------KVAIKVIDKEKIMKSGLVAHIKREISILRRVRHPYIVHLFEVMATKS 145
Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
+ V EYV G L +G +P QQL S++S+ + + H ++ N+L
Sbjct 146 KIYFVMEYVGGGELFN--TVAKGRLPEETARRYFQQLISSVSFCHGRGVYHRDLKPENLL 203
Query 742 LARLGLAEGTSPFIKLSDPGVG------LGALSREERVERIPWLAPECLPGGANSLSTAM 795
L G +K+SD G+ ++APE L +
Sbjct 204 LDNKG-------NLKVSDFGLSAVAEQLRQDGLCHTFCGTPAYIAPEVLTRKGYD-AAKA 255
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPT 854
D W G L + G P ++ + R P L L ++ L P
Sbjct 256 DVWSCGVIL-FVLMAGHIPFYDKNIMVMYKKIYKGEFRCPRWFSSDLVRLLTRLLDTNPD 314
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
R + I+++ + +
Sbjct 315 TRITIPEIMKNRWFKKGFKHVKFYIEDDKLCR 346
>sp|Q5R754|CDKL2_PONAB Cyclin-dependent kinase-like 2 OS=Pongo
abelii OX=9601 GN=CDKL2 PE=2 SV=1
Length=493
Score = 224 bits (571), Expect = 3e-62, Method: Composition-based stats.
Identities = 75/283 (27%), Positives = 119/283 (42%), Gaps = 27/283 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG +G V N TG +VA+K L++D + +EI +L+ L HE+++
Sbjct 10 VGEGSYGMVM----KCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
C + +K LV E+V L D L + + + + QI G+ + H+ + I
Sbjct 66 LLEVC--KKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNII 123
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFY 1079
HRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L K+
Sbjct 124 HRDIKPENILVSKSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVKYG 180
Query 1080 YASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
A DVW+ G + E+ DS + +G + L + G RL
Sbjct 181 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFYKNPVFAGVRL 240
Query 1135 P----------RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P R K V L K C + RP L+
Sbjct 241 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLH 283
Score = 162 bits (409), Expect = 6e-41, Method: Composition-based stats.
Identities = 56/320 (18%), Positives = 101/320 (32%), Gaps = 70/320 (22%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-L 644
++ L +G+G+ V + R + G V +K L
Sbjct 1 MEKYENLGLVGEGSYGMVMKCRNKDTGR------------------------IVAIKKFL 36
Query 645 DPSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ + L+ Q+ H +L + VC + +V E+V+H LD L
Sbjct 37 ESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDD-LELFP 95
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ Q+ + + + + N++H ++ NIL+++ G+ +KL D G
Sbjct 96 NGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSKSGV-------VKLCDFGFA 148
Query 764 LGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ + V + APE L G A+D W G + E+
Sbjct 149 RTLAAPGEVYTDYVATRWYRAPELLV-GDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSD 207
Query 820 PSEKEHFYQ-------------------RQHRLPEPS------------CPQLATLTSQC 848
+ H RLPE + L +C
Sbjct 208 IDQLYHIMMCLGNLIPRHQELFYKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKC 267
Query 849 LTYEPTQRPSFRTILRDLTR 868
L +P +RP +L
Sbjct 268 LHIDPDKRPFCAELLHHDFF 287
>sp|Q9SCZ4|FERON_ARATH Receptor-like protein kinase FERONIA OS=Arabidopsis
thaliana OX=3702 GN=FER PE=1 SV=1
Length=895
Score = 233 bits (594), Expect = 3e-62, Method: Composition-based stats.
Identities = 79/315 (25%), Positives = 131/315 (42%), Gaps = 19/315 (6%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
+ + + R LG G FGKV D GT VA+K Q
Sbjct 521 CRHFSFAEIKAATKNFDESRVLGVGGFGKVYRGEIDG---GT-TKVAIKRGNP-MSEQGV 575
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLA 998
++ EI++L L H H++ G CE+ E + LV +Y+ G++R++L S+
Sbjct 576 HEFQTEIEMLSKLRHRHLVSLIGYCEENCE--MILVYDYMAHGTMREHLYKTQNPSLPWK 633
Query 999 QLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
Q L G+ YLH IHRD+ N+LLD + K+ DFGL+K P ++
Sbjct 634 QRLEICIGAARGLHYLHTGAKHTIIHRDVKTTNILLDEKWVAKVSDFGLSKTGP-TLDHT 692
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
V + PE + + SDV+SFGV L+E L C PT E + +A
Sbjct 693 HVSTVVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLFEAL--CARPALNPTLAKEQVSLA 750
Query 1116 QGQMTVLR---LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ + L ++++ + +C + C + RP+ +++ L+
Sbjct 751 EWAPYCYKKGMLDQIVDPYLKGKITPECFKKFAETAMKCVLDQGIERPSMGDVLWNLEFA 810
Query 1173 HEKYQGQAPSVFSVC 1187
+ + + VC
Sbjct 811 LQLQESAEENGKGVC 825
Score = 218 bits (554), Expect = 4e-57, Method: Composition-based stats.
Identities = 68/312 (22%), Positives = 108/312 (35%), Gaps = 52/312 (17%)
Query 559 SNLIIMRGARASPRTLNL-SQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615
S G+ AS NL SF + K + LG G VY G +
Sbjct 503 SAKTNTTGSYASSLPSNLCRHFSFAEIKAATKNFDESRVLGVGGFGKVYRGEI------- 555
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675
G +V +K +P F ++S++ H HL + G
Sbjct 556 -----------------DGGTTKVAIKRGNPMSEQGVHEFQTEIEMLSKLRHRHLVSLIG 598
Query 676 VCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLE---NKNLV 731
C E I+V +Y+ HG + L + + +P ++ + A L YL ++
Sbjct 599 YCEENCEMILVYDYMAHGTMREHLYKTQNPSLPWKQRLEICIGAARGLHYLHTGAKHTII 658
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVERI-----PWLAPECLP 785
H +V NILL +A K+SD G+ G V + +L PE
Sbjct 659 HRDVKTTNILLDEKWVA-------KVSDFGLSKTGPTLDHTHVSTVVKGSFGYLDPEYFR 711
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSR-----SPSEKEHFYQRQHRLPEPSCPQ 840
L+ D + FG L E A + S +E + ++ L + P
Sbjct 712 --RQQLTEKSDVYSFGVVLFEALCARPALNPTLAKEQVSLAEWAPYCYKKGMLDQIVDPY 769
Query 841 LA-TLTSQCLTY 851
L +T +C
Sbjct 770 LKGKITPECFKK 781
>sp|Q6FN53|STE20_CANGA Serine/threonine-protein kinase STE20 OS=Candida
glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761
/ NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=STE20 PE=3
SV=1
Length=915
Score = 233 bits (595), Expect = 3e-62, Method: Composition-based stats.
Identities = 62/282 (22%), Positives = 120/282 (43%), Gaps = 25/282 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G G V + + + + VA+K + + P+ + EI ++R H +I+
Sbjct 625 KIGQGASGGVYIAH----DTESEDSVAIKQMNLEKQPK-KELILNEILVMRESKHSNIVN 679
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
+ +G+ L +VMEY+ GSL D + + Q+ ++ +G+ +LH++ +H
Sbjct 680 FIDSYLAKGD--LWIVMEYMEGGSLTDVVTHCLLSEGQIGAVCRETLKGLQFLHSKGVLH 737
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RD+ + N+LL +K+ DFG + E + R +W APE + ++
Sbjct 738 RDIKSDNILLSLKGNIKLTDFGFCAQINENNL---KRTTMVGTPYWMAPEVVSRKEYGPK 794
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
D+WS G+ + E++ + T L IA +L P+
Sbjct 795 VDIWSLGIMIIEMI-EGEPPYLNETPLRALYLIATNGTP------------KLKEPEALS 841
Query 1142 CEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAP 1181
+ + C + + S R T L+ P + + E +P
Sbjct 842 DTLTKFLDWCLKVDPSERATATELLDDPFITEIAEDNSSLSP 883
Score = 187 bits (474), Expect = 4e-47, Method: Composition-based stats.
Identities = 56/295 (19%), Positives = 101/295 (34%), Gaps = 44/295 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L+++ + + L +GQG VY D
Sbjct 607 LTEICSPGDPKSKYRDLIKIGQGASGGVY------------------------IAHDTES 642
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
E V +K ++ +M + H+++ + + +V EY+E G L
Sbjct 643 EDSVAIKQMNLEKQPKKELILNEILVMRESKHSNIVNFIDSYLAKGDLWIVMEYMEGGSL 702
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+ + V ++ L +L +K ++H ++ NILL+ G I
Sbjct 703 TDVVTH--CLLSEGQIGAVCRETLKGLQFLHSKGVLHRDIKSDNILLSLKG-------NI 753
Query 756 KLSDPGVGLGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D G L R V W+APE + +D W G ++E+ +G
Sbjct 754 KLTDFGFCAQINENNLKRTTMVGTPYWMAPEVVS--RKEYGPKVDIWSLGIMIIEMI-EG 810
Query 812 EAPLQSRSPSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
E P + +P + PE L CL +P++R + +
Sbjct 811 EPPYLNETPLRALYLIATNGTPKLKEPEALSDTLTKFLDWCLKVDPSERATATEL 865
>sp|Q68Y49|CIPKJ_ORYSJ CBL-interacting protein kinase 19 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK19 PE=1 SV=1
Length=508
Score = 224 bits (572), Expect = 3e-62, Method: Composition-based stats.
Identities = 63/270 (23%), Positives = 108/270 (40%), Gaps = 30/270 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960
LG G F KV Y + +GE VA+K L + +H K+EI ILR + H +I+
Sbjct 43 LGHGTFAKV----YQARSADSGEPVAIKVLDKEKAMRHGLVPHIKREIAILRRVRHPNIV 98
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ + + + VME V G L + + + + QQ+ + + HA+
Sbjct 99 RLFEVMATKSK--IYFVMELVRGGELFGRVAKGRLKEDTARRYFQQLVSAVGFCHARGVF 156
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
HRDL N+L+D +K+ DFGL+ + H + +P + APE L +
Sbjct 157 HRDLKPENLLVDEHGDLKVSDFGLSAVADQFHPDGLLHTFCGTPS-YVAPEVLARRGYDG 215
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP--RP 1137
+D+WS G+ L+ L+ L + + R P
Sbjct 216 AKADIWSCGIILFVLMAGYLPFHD------------------QNLMAMYRKIYRGEFRCP 257
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
++ L+ +T R T + ++
Sbjct 258 RWFSKDLSSLLNRILDTNPETRITVKEVME 287
Score = 180 bits (456), Expect = 6e-47, Method: Composition-based stats.
Identities = 54/305 (18%), Positives = 94/305 (31%), Gaps = 43/305 (14%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH- 648
LG GT VY+ R G V +KVLD
Sbjct 38 ELGRLLGHGTFAKVYQARSADSGE------------------------PVAIKVLDKEKA 73
Query 649 --HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
H + +++ +V H ++ + V + V E V G L R +G +
Sbjct 74 MRHGLVPHIKREIAILRRVRHPNIVRLFEVMATKSKIYFVMELVRGGELFG--RVAKGRL 131
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
QQL SA+ + + + H ++ N+L+ G +K+SD G+ A
Sbjct 132 KEDTARRYFQQLVSAVGFCHARGVFHRDLKPENLLVDEHGD-------LKVSDFGLSAVA 184
Query 767 LS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
++APE L D W G L +
Sbjct 185 DQFHPDGLLHTFCGTPSYVAPEVLARRGYD-GAKADIWSCGIILFVLMAGYLPFHDQNLM 243
Query 821 SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880
+ Y+ + R P L++L ++ L P R + + ++ +
Sbjct 244 AMYRKIYRGEFRCPRWFSKDLSSLLNRILDTNPETRITVKEVMESRWFQKGFRPVRFYVE 303
Query 881 NPDSP 885
+
Sbjct 304 DDQVH 308
>sp|P52497|SNF1_CANAX Carbon catabolite-derepressing protein kinase
OS=Candida albicans OX=5476 GN=SNF1 PE=2 SV=2
Length=620
Score = 228 bits (580), Expect = 3e-62, Method: Composition-based stats.
Identities = 77/327 (24%), Positives = 123/327 (38%), Gaps = 30/327 (9%)
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
S+ + + H+ + + + ++ LG
Sbjct 1 MSEQAQPQASADQQQHQHNHHHHHHHHHHNENQSQQQVPIDPAANPANRIGRYQILKTLG 60
Query 905 EGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG--WKQEIDILRTLYHEHIIKY 962
EG FGKV L + GTG+ VA+K + + ++EI LR L H HIIK
Sbjct 61 EGSFGKVKL----AQHLGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHPHIIKL 116
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
+ + E + +V+E+ L DY+ R + + F QQI + Y H +H
Sbjct 117 YDVIKSKDE--IIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHKIVH 173
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF-YY 1080
RDL N+LLD+ VKI DFGL+ + +G+ ++ SP + APE + +
Sbjct 174 RDLKPENLLLDDQLNVKIADFGLSNIMTDGN---FLKTSCGSPNYMPAPEVISGKLYAGP 230
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
DVWS GV LY +L + L + + G P+
Sbjct 231 EVDVWSAGVILYVMLCGRLPFDDEF---------------IPALFKKISNGV-YTLPNYL 274
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIP 1167
HL+ R T ++
Sbjct 275 SAGAKHLLTRMLVVNPLNRITIHEIME 301
Score = 176 bits (445), Expect = 1e-44, Method: Composition-based stats.
Identities = 54/298 (18%), Positives = 98/298 (33%), Gaps = 37/298 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+R+ + +I L LG+G+ V + G +
Sbjct 48 NRIGRYQI--LKTLGEGSFGKVKLAQHLGTGQKVALKIINR------------------- 86
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
K L S + S + + H H+ ++ V E IMV E+ L ++
Sbjct 87 KTLAKSDMQGRVE--REISYLRLLRHPHIIKLYDVIKSKDEIIMVIEFA-GKELFDYI-V 142
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
+RG +P QQ+ +A+ Y +VH ++ N+LL +K++D G
Sbjct 143 QRGKMPEDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLLLDDQL-------NVKIADFG 195
Query 762 VGLGALSR---EERVERIPWL-APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ + ++ APE + G + +D W G L +
Sbjct 196 LSNIMTDGNFLKTSCGSPNYMPAPEVISGKLYA-GPEVDVWSAGVILYVMLCGRLPFDDE 254
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
P+ + + LP L ++ L P R + I+ D Q
Sbjct 255 FIPALFKKISNGVYTLPNYLSAGAKHLLTRMLVVNPLNRITIHEIMEDDWFKQDMPDY 312
>sp|Q9S9U1|LRK71_ARATH L-type lectin-domain containing receptor
kinase VII.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK71 PE=2
SV=1
Length=686
Score = 229 bits (584), Expect = 3e-62, Method: Composition-based stats.
Identities = 66/305 (22%), Positives = 122/305 (40%), Gaps = 23/305 (8%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ P + + + +G G GKV Y G VAVK + +
Sbjct 328 MEYWPHRIPYEEIESGTKGFDEKNVIGIGGNGKV----YKGLLQGGVVEVAVKRISQESS 383
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---- 993
R + EI L L H +++ +G C+ + S LV +Y+ GSL ++ +
Sbjct 384 DGMRE-FVAEISSLGRLKHRNLVSLRGWCK-KEVGSFMLVYDYMENGSLDRWIFENDEKI 441
Query 994 -SIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
++ + + + + G+ YLH +HRD+ A NVLLD D + ++ DFGLA+
Sbjct 442 TTLSCEERIRILKGVASGILYLHEGWESKVLHRDIKASNVLLDRDMIPRLSDFGLARV-- 499
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
GHE + APE +K + +DV+++G+ + E++ +
Sbjct 500 HGHEQPVRTTRVVGTAGYLAPEVVKTGRASTQTDVFAYGILVLEVMCGRRPIEEGKKP-- 557
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPD----KCPCEVYHLMKNCWETEASFRPTFENL 1165
L+ G M + L+ + + V L C + + RP+ +
Sbjct 558 -LMDWVWGLMERGEILNGLDPQMMMTQGVTEVIDEAERVLQLGLLCAHPDPAKRPSMRQV 616
Query 1166 IPILK 1170
+ + +
Sbjct 617 VQVFE 621
Score = 198 bits (503), Expect = 9e-52, Method: Composition-based stats.
Identities = 60/317 (19%), Positives = 114/317 (36%), Gaps = 69/317 (22%)
Query 582 HRVDQKEIT-------QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
HR+ +EI + + +G G VY+G L +G
Sbjct 333 HRIPYEEIESGTKGFDEKNVIGIGGNGKVYKGLL------------------------QG 368
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHG 693
+ V +K + D F S + ++ H +L + G C + ++V +Y+E+G
Sbjct 369 GVVEVAVKRISQESSDGMREFVAEISSLGRLKHRNLVSLRGWCKKEVGSFMLVYDYMENG 428
Query 694 PLDVWLRRERGHVPM---AWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGL 747
LD W+ + ++ + + +AS + YL ++H ++ N+LL R +
Sbjct 429 SLDRWIFENDEKITTLSCEERIRILKGVASGILYLHEGWESKVLHRDIKASNVLLDRDMI 488
Query 748 AEGTSPFIKLSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+LSD G+ + V +LAPE + G ST D + +G
Sbjct 489 P-------RLSDFGLARVHGHEQPVRTTRVVGTAGYLAPEVVKTGRA--STQTDVFAYGI 539
Query 803 TLLEICFDGEAPLQSRSP-----------------SEKEHFYQRQHRLPEPSCPQLATLT 845
+LE+ + + P + + + ++ L
Sbjct 540 LVLEVMCGRRPIEEGKKPLMDWVWGLMERGEILNGLDPQMMMTQGVTEVIDEAERVLQLG 599
Query 846 SQCLTYEPTQRPSFRTI 862
C +P +RPS R +
Sbjct 600 LLCAHPDPAKRPSMRQV 616
>sp|Q09092|SRK6_BRAOV Putative serine/threonine-protein kinase
receptor OS=Brassica oleracea var. viridis OX=3713 GN=SRK6
PE=1 SV=2
Length=857
Score = 232 bits (592), Expect = 3e-62, Method: Composition-based stats.
Identities = 67/302 (22%), Positives = 115/302 (38%), Gaps = 24/302 (8%)
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G FG V G+ +AVK L Q + E+ ++ L H ++
Sbjct 531 CNKLGQGGFGIVYKGRL-----LDGKEIAVKRLSK-TSVQGTDEFMNEVTLIARLQHINL 584
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015
++ GCC + EK L+ EY+ SL YL R + + + G+ YLH
Sbjct 585 VQVLGCCIEGDEK--MLIYEYLENLSLDSYLFGKTRRSKLNWNERFDITNGVARGLLYLH 642
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
IHRDL N+LLD + + KI DFG+A+ + + +PE
Sbjct 643 QDSRFRIIHRDLKVSNILLDKNMIPKISDFGMARIFERDETEANTMK-VVGTYGYMSPEY 701
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQ----SPPTKFLELIGIAQGQMTVLRLTELL 1128
F SDV+SFGV + E+++ + L + + L + + +
Sbjct 702 AMYGIFSEKSDVFSFGVIVLEIVSGKKNRGFYNLDYENDLLSYVWSRWKEGRALEIVDPV 761
Query 1129 ERGERLPRPDKCPC----EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
+P + + C + A RP +++ + + + P +
Sbjct 762 IVDSLSSQPSIFQPQEVLKCIQIGLLCVQELAEHRPAMSSVVWMFGSEATEIPQPKPPGY 821
Query 1185 SV 1186
V
Sbjct 822 CV 823
Score = 226 bits (576), Expect = 4e-60, Method: Composition-based stats.
Identities = 62/350 (18%), Positives = 114/350 (33%), Gaps = 53/350 (15%)
Query 559 SNLIIMRGARASPRTLNLSQLSFHRVD-------QKEITQLSHLGQGTRTNVYEGRLRVE 611
N +++ R +L ++ + + + LGQG VY+GRL
Sbjct 491 MNEMVLSSKREFSGEYKFEELELPLIEMETVVKATENFSSCNKLGQGGFGIVYKGRLLDG 550
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
+ +K L + F +L++++ H +L
Sbjct 551 K-------------------------EIAVKRLSKTSVQGTDEFMNEVTLIARLQHINLV 585
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENK- 728
V G C+ G E +++ EY+E+ LD +L R + + + +A L YL
Sbjct 586 QVLGCCIEGDEKMLIYEYLENLSLDSYLFGKTRRSKLNWNERFDITNGVARGLLYLHQDS 645
Query 729 --NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLA 780
++H ++ NILL + + K+SD G+ E V +++
Sbjct 646 RFRIIHRDLKVSNILLDK-------NMIPKISDFGMARIFERDETEANTMKVVGTYGYMS 698
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840
PE G S D + FG +LEI + E + R E +
Sbjct 699 PEYAMYGI--FSEKSDVFSFGVIVLEIVSGKKNRGFYNLDYENDLLSYVWSRWKEGRALE 756
Query 841 LAT-LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
+ + L+ +P+ + L S
Sbjct 757 IVDPVIVDSLSSQPSIFQPQEVLKCIQIGLLCVQELAEHRPAMSSVVWMF 806
>sp|Q9ES70|NEK6_MOUSE Serine/threonine-protein kinase Nek6 OS=Mus
musculus OX=10090 GN=Nek6 PE=1 SV=1
Length=313
Score = 218 bits (555), Expect = 3e-62, Method: Composition-based stats.
Identities = 61/285 (21%), Positives = 116/285 (41%), Gaps = 30/285 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTL 954
+ + +G G F +V Y T + VA+K ++ + R +EI +L+ L
Sbjct 45 FQIEKKIGRGQFSEV----YKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQL 100
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICE 1009
H +IIKY + E L +V+E G L + + I + + Q+C
Sbjct 101 NHPNIIKYLDSFIEDNE--LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCS 158
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ ++H++ +HRD+ NV + +VK+GD GL + ++ +
Sbjct 159 AVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFS---SETTAAHSLVGTPYYMS 215
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE + E + + SD+WS G LYE+ +M + L + +E
Sbjct 216 PERIHENGYNFKSDIWSLGCLLYEMAALQSPFYG-------------DKMNLFSLCQKIE 262
Query 1130 RGERLPRP-DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ + P P + ++ L+ C + RP + + + +H
Sbjct 263 QCDYPPLPGEHYSEKLRELVSMCIYPDPDHRPDIVYVHQVARQMH 307
Score = 171 bits (433), Expect = 8e-46, Method: Composition-based stats.
Identities = 53/332 (16%), Positives = 108/332 (33%), Gaps = 41/332 (12%)
Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
+P G ++L G P L R + +G+G + VY+ ++
Sbjct 8 MPHGGSPNHLCHALGPAPPPDPQRLPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLD 67
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
+ E R +K L+ Q++H ++
Sbjct 68 RKTVALKKVQIFEMMDAKARQD------CVK---------------EIGLLKQLNHPNII 106
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDV---WLRRERGHVPMAWKMVVAQQLASALSYLENK 728
+ E +V E + G L + ++++ +P QL SA+ ++ ++
Sbjct 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 166
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER----VERIPWLAPECL 784
++H ++ N+ + G+ +KL D G+G S V +++PE +
Sbjct 167 RVMHRDIKPANVFITATGI-------VKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERI 219
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS----EKEHFYQRQHRLPEPSCPQ 840
+ D W G L E+ + +K E +
Sbjct 220 HENGYNF--KSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEK 277
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
L L S C+ +P RP + + ++
Sbjct 278 LRELVSMCIYPDPDHRPDIVYVHQVARQMHVW 309
>sp|P38692|KIC1_YEAST Serine/threonine-protein kinase KIC1 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=KIC1 PE=1 SV=1
Length=1080
Score = 235 bits (599), Expect = 3e-62, Method: Composition-based stats.
Identities = 70/269 (26%), Positives = 117/269 (43%), Gaps = 29/269 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH-EHIIK 961
+G G FG V Y N TG + A+K L D ++EI L +L +I +
Sbjct 29 IGRGKFGVV----YKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITR 84
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
Y G + SL ++ME+ GSLR L I + + +++ + +H + IH
Sbjct 85 YYGSYLK--DTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIH 142
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-Y 1080
RD+ A NVL+ N+ VK+ DFG+A V + R+ +W APE + E +Y
Sbjct 143 RDIKAANVLITNEGNVKLCDFGVAAQVNQTSLR---RQTMAGTPYWMAPEVIMEGVYYDT 199
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK- 1139
D+WS G+T YE+ T + LR +L+ + + PR +
Sbjct 200 KVDIWSLGITTYEIATGNPP---------------YCDVEALRAMQLIIKS-KPPRLEDR 243
Query 1140 -CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + C + + R + ++L+
Sbjct 244 SYSTSLKEFIALCLDEDPKERLSADDLLK 272
Score = 183 bits (464), Expect = 1e-45, Method: Composition-based stats.
Identities = 55/277 (20%), Positives = 98/277 (35%), Gaps = 44/277 (16%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD-PS 647
+ +G+G VY+G G +KVL+ S
Sbjct 23 FKRTEVIGRGKFGVVYKGYNVKTGRVY------------------------AIKVLNLDS 58
Query 648 HHDIALAFYETASLMSQVSH-THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
D ++ + +++ +G ++ ++ E+ G L LR G +
Sbjct 59 DSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLR--PGKI 116
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--- 763
+ V+ ++L AL + N++H ++ N+L+ G +KL D GV
Sbjct 117 DEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEG-------NVKLCDFGVAAQV 169
Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP-- 820
+L R+ W+APE + G T +D W G T EI G P
Sbjct 170 NQTSLRRQTMAGTPYWMAPEVIMEGVY-YDTKVDIWSLGITTYEIA-TGNPPYCDVEALR 227
Query 821 SEKEHFYQRQHRLPEP-SCPQLATLTSQCLTYEPTQR 856
+ + + RL + L + CL +P +R
Sbjct 228 AMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKER 264
>sp|Q9C8I6|IOS1_ARATH LRR receptor-like serine/threonine-protein
kinase IOS1 OS=Arabidopsis thaliana OX=3702 GN=IOS1 PE=1
SV=1
Length=894
Score = 233 bits (594), Expect = 3e-62, Method: Composition-based stats.
Identities = 70/306 (23%), Positives = 121/306 (40%), Gaps = 18/306 (6%)
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932
+ V + K R LG G FG V E VAVK L
Sbjct 562 HHGFEPPVIAKNRKLTYIDVVKITNNFERVLGRGGFGVVYYGVL------NNEPVAVKML 615
Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992
+ +K E+++L ++H+ + G CE+ + + L+ E++ G L+++L
Sbjct 616 -TESTALGYKQFKAEVELLLRVHHKDLTCLVGYCEEGDK--MSLIYEFMANGDLKEHLSG 672
Query 993 HS----IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+ L A + +G+ YLH +HRD+ N+LL+ K+ DFGL+
Sbjct 673 KRGPSILTWEGRLRIAAESAQGLEYLHNGCKPQIVHRDIKTTNILLNEKFQAKLADFGLS 732
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
++ P G E + +P + PE + SDV+SFGV L EL+T+
Sbjct 733 RSFPLGTETHVSTIVAGTP-GYLDPEYYRTNWLTEKSDVFSFGVVLLELVTNQPVIDMKR 791
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
K + ++ + +++ + +V C +S RPT +
Sbjct 792 EK-SHIAEWVGLMLSRGDINSIVDPKLQGDFDPNTIWKVVETAMTCLNPSSSRRPTMTQV 850
Query 1166 IPILKT 1171
+ LK
Sbjct 851 VMDLKE 856
Score = 203 bits (516), Expect = 2e-52, Method: Composition-based stats.
Identities = 75/346 (22%), Positives = 118/346 (34%), Gaps = 61/346 (18%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
P +L++ V + LG+G VY G L E
Sbjct 566 EPPVIAKNRKLTYIDVVKITNNFERVLGRGGFGVVYYGVLNNE----------------- 608
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
V +K+L S F L+ +V H L + G C G + ++ E
Sbjct 609 ---------PVAVKMLTESTALGYKQFKAEVELLLRVHHKDLTCLVGYCEEGDKMSLIYE 659
Query 689 YVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLA 743
++ +G L L +RG + W ++ +A + A L YL N +VH ++ NILL
Sbjct 660 FMANGDLKEHLSGKRGPSILTWEGRLRIAAESAQGLEYLHNGCKPQIVHRDIKTTNILLN 719
Query 744 RLGLAEGTSPFIKLSDPGVGLG-ALSREERVERI-----PWLAPECLPGGANSLSTAMDK 797
A KL+D G+ L E V I +L PE N L+ D
Sbjct 720 EKFQA-------KLADFGLSRSFPLGTETHVSTIVAGTPGYLDPEYYRT--NWLTEKSDV 770
Query 798 WGFGATLLEICFDGEAPLQSRSPS---EKEHFYQRQHRLPEPSCPQL------------A 842
+ FG LLE+ + R S E + + P+L
Sbjct 771 FSFGVVLLELVTNQPVIDMKREKSHIAEWVGLMLSRGDINSIVDPKLQGDFDPNTIWKVV 830
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASD 888
CL ++RP+ ++ DL +A + +D
Sbjct 831 ETAMTCLNPSSSRRPTMTQVVMDLKECLNMEMARNMGSRMTDSTND 876
>sp|P54666|CC2H3_TRYBB Cell division control protein 2 homolog
3 OS=Trypanosoma brucei brucei OX=5702 GN=CRK3 PE=3 SV=1
Length=311
Score = 218 bits (555), Expect = 3e-62, Method: Composition-based stats.
Identities = 70/290 (24%), Positives = 120/290 (41%), Gaps = 29/290 (10%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDIL 951
++ LGEG +G V Y + TG++VA+K ++ D + +E+ IL
Sbjct 19 QFDRYNRMDILGEGTYGVV----YRAVDRATGQIVALKKVRLDRTDEGIPQTALREVSIL 74
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICE 1009
+ ++H +I+ G+ L L+ EYV L+ L + L Q+ E
Sbjct 75 QEIHHPNIVNLLDVICADGK--LYLIFEYVDH-DLKKALEKRGGAFTGTTLKKIIYQLLE 131
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
G+++ H +HRDL N+L+ D VKI DFGLA+A Y +++ A
Sbjct 132 GLSFCHRHRIVHRDLKPANILVTTDNSVKIADFGLARAFQIPMHTY---THEVVTLWYRA 188
Query 1070 PECLKEYK-FYYASDVWSFGVTLYEL-----LTHCDSSQSPPTKFLELIGIA-QGQMTVL 1122
PE L K + A D+WS G EL L DS + +++G + + L
Sbjct 189 PEILLGEKHYTPAVDMWSIGCIFAELARGKVLFRGDSEIGQLFEIFQVLGTPMDAEGSWL 248
Query 1123 RLTELLERGERLPRPDKCPC---------EVYHLMKNCWETEASFRPTFE 1163
++ L + + P+ P + L+ + R + +
Sbjct 249 GVSSLPDYRDVFPKWSGKPLTQVLPTLDGDAVDLLSQMLRYNPAERISAK 298
Score = 173 bits (439), Expect = 1e-46, Method: Composition-based stats.
Identities = 48/223 (22%), Positives = 80/223 (36%), Gaps = 39/223 (17%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--VLDPSH 648
++ LG+GT VY DR V LK LD +
Sbjct 25 RMDILGEGTYGVVYRAV------------------------DRATGQIVALKKVRLDRTD 60
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
I S++ ++ H ++ + V + ++ EYV+H L L + G
Sbjct 61 EGIPQTALREVSILQEIHHPNIVNLLDVICADGKLYLIFEYVDH-DLKKALEKRGGAFTG 119
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG--- 765
+ QL LS+ +VH ++ NIL+ T +K++D G+
Sbjct 120 TTLKKIIYQLLEGLSFCHRHRIVHRDLKPANILVT-------TDNSVKIADFGLARAFQI 172
Query 766 -ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+ V + + APE L G + A+D W G E+
Sbjct 173 PMHTYTHEVVTLWYRAPEILL-GEKHYTPAVDMWSIGCIFAEL 214
>sp|Q9LMT9|WAKLL_ARATH Putative wall-associated receptor kinase-like
13 OS=Arabidopsis thaliana OX=3702 GN=WAKL13 PE=3 SV=1
Length=764
Score = 231 bits (588), Expect = 4e-62, Method: Composition-based stats.
Identities = 77/301 (26%), Positives = 118/301 (39%), Gaps = 24/301 (8%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R +G+G G V G VAVK + E+ IL +
Sbjct 452 DNFNDNRVIGQGGQGTVYKGML-----VDGRSVAVKKSNV-VDEDKLQEFINEVIILSQI 505
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEG 1010
H H++K GCC + E + LV E++P G+L +L ++ + A I
Sbjct 506 NHRHVVKLLGCCLE-TEVPI-LVYEFIPNGNLFQHLHEEFDDYTALWGVRMRIAVDISGA 563
Query 1011 MAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+YLH HRD+ + N+LLD K+ DFG +++V H ++ V +
Sbjct 564 FSYLHTAACSPIYHRDIKSTNILLDEKYRAKVSDFGTSRSVSIDHTHWTT--VISGTVGY 621
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLT 1125
PE F SDV+SFGV L EL+T + S + L + M RL
Sbjct 622 VDPEYYGSSHFTEKSDVYSFGVVLVELITGEKPVITLSETQEITGLADYFRLAMRENRLF 681
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
E+++ R + V +L C + RP + L+ + AP F
Sbjct 682 EIIDARIRNDCKLEQVIAVANLALRCLKKTGKTRPDMREVSTALERIC-----SAPEDFQ 736
Query 1186 V 1186
V
Sbjct 737 V 737
Score = 216 bits (550), Expect = 3e-57, Method: Composition-based stats.
Identities = 73/378 (19%), Positives = 128/378 (34%), Gaps = 82/378 (22%)
Query 536 CLLRAGDDCFSLRRCCLPQP---------GETSNLII------MRGARASPRTLNLSQLS 580
+L G + R+ + L++ +G + + +L
Sbjct 389 FVLIVGGGIWWWRKLLRKRRMTNRKRKFFKRNGGLLLQQQLNTTQGRVEKTKLFSSRELE 448
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
+GQG + VY+G L S V
Sbjct 449 K---ATDNFNDNRVIGQGGQGTVYKGMLVDGRS-------------------------VA 480
Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
+K + D F ++SQ++H H+ + G C+ I+V E++ +G L L
Sbjct 481 VKKSNVVDEDKLQEFINEVIILSQINHRHVVKLLGCCLETEVPILVYEFIPNGNLFQHLH 540
Query 701 RERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFI 755
E W +M +A ++ A SYL + H ++ NILL A
Sbjct 541 EEFDDYTALWGVRMRIAVDISGAFSYLHTAACSPIYHRDIKSTNILLDEKYRA------- 593
Query 756 KLSDPGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K+SD G + ++ PE G++ + D + FG L+E+
Sbjct 594 KVSDFGTSRSVSIDHTHWTTVISGTVGYVDPEYY--GSSHFTEKSDVYSFGVVLVELI-T 650
Query 811 GEAPLQSRSPSEKE-------HFYQRQHRLPEPSCPQL------------ATLTSQCLTY 851
GE P+ + S +++ R++RL E ++ A L +CL
Sbjct 651 GEKPVITLSETQEITGLADYFRLAMRENRLFEIIDARIRNDCKLEQVIAVANLALRCLKK 710
Query 852 EPTQRPSFRTILRDLTRL 869
RP R + L R+
Sbjct 711 TGKTRPDMREVSTALERI 728
>sp|P35465|PAK1_RAT Serine/threonine-protein kinase PAK 1 OS=Rattus
norvegicus OX=10116 GN=Pak1 PE=1 SV=3
Length=544
Score = 225 bits (574), Expect = 4e-62, Method: Composition-based stats.
Identities = 72/370 (19%), Positives = 132/370 (36%), Gaps = 25/370 (7%)
Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
P+ + P + Y R P P P + + ++ + R+ + +
Sbjct 186 PPVIAPRPEHTKSVYTRSVIEPLPVTPT-RDVATSPISPTENNTTPPDALTRNTEKQKKK 244
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932
+ + K+ + +G+G G V Y + TG+ VA+K +
Sbjct 245 PKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV----YTAMDVATGQEVAIKQM 300
Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992
P+ + EI ++R + +I+ Y E L +VMEY+ GSL D +
Sbjct 301 NLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTE 357
Query 993 HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
+ Q+ ++ + + +LH+ IHRD+ + N+LL D VK+ DFG +
Sbjct 358 TCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITP-- 415
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
R +W APE + + D+WS G+ E++ PP +
Sbjct 416 -EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI-----EGEPPYLNENPL 469
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP-ILKT 1171
T L P+K + C E + R + + L+
Sbjct 470 RALYLIATNGT--------PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLK 521
Query 1172 VHEKYQGQAP 1181
+ + P
Sbjct 522 IAKPLSSLTP 531
Score = 181 bits (458), Expect = 6e-47, Method: Composition-based stats.
Identities = 54/291 (19%), Positives = 97/291 (33%), Gaps = 44/291 (15%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+K+ T+ +GQG VY D V +K +
Sbjct 265 PKKKYTRFEKIGQGASGTVY------------------------TAMDVATGQEVAIKQM 300
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ +M + + ++ + G E +V EY+ G L +
Sbjct 301 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 358
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ V ++ AL +L + ++H ++ NILL G +KL+D G
Sbjct 359 CMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 411
Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
R V W+APE + A +D W G +E+ +GE P + +P
Sbjct 412 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMI-EGEPPYLNENP 468
Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ PE ++CL + +R S + +L+
Sbjct 469 LRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF 519
>sp|Q13153|PAK1_HUMAN Serine/threonine-protein kinase PAK 1 OS=Homo
sapiens OX=9606 GN=PAK1 PE=1 SV=2
Length=545
Score = 225 bits (574), Expect = 4e-62, Method: Composition-based stats.
Identities = 72/370 (19%), Positives = 132/370 (36%), Gaps = 25/370 (7%)
Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
P+ + P + Y R P P P + + ++ + R+ + +
Sbjct 187 PPVIAPRPEHTKSVYTRSVIEPLPVTPT-RDVATSPISPTENNTTPPDALTRNTEKQKKK 245
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932
+ + K+ + +G+G G V Y + TG+ VA+K +
Sbjct 246 PKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV----YTAMDVATGQEVAIKQM 301
Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992
P+ + EI ++R + +I+ Y E L +VMEY+ GSL D +
Sbjct 302 NLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTE 358
Query 993 HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
+ Q+ ++ + + +LH+ IHRD+ + N+LL D VK+ DFG +
Sbjct 359 TCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITP-- 416
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
R +W APE + + D+WS G+ E++ PP +
Sbjct 417 -EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI-----EGEPPYLNENPL 470
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP-ILKT 1171
T L P+K + C E + R + + L+
Sbjct 471 RALYLIATNGT--------PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLK 522
Query 1172 VHEKYQGQAP 1181
+ + P
Sbjct 523 IAKPLSSLTP 532
Score = 181 bits (458), Expect = 6e-47, Method: Composition-based stats.
Identities = 54/291 (19%), Positives = 97/291 (33%), Gaps = 44/291 (15%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+K+ T+ +GQG VY D V +K +
Sbjct 266 PKKKYTRFEKIGQGASGTVY------------------------TAMDVATGQEVAIKQM 301
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ +M + + ++ + G E +V EY+ G L +
Sbjct 302 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 359
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ V ++ AL +L + ++H ++ NILL G +KL+D G
Sbjct 360 CMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 412
Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
R V W+APE + A +D W G +E+ +GE P + +P
Sbjct 413 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMI-EGEPPYLNENP 469
Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ PE ++CL + +R S + +L+
Sbjct 470 LRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF 520
>sp|Q03497|STE20_YEAST Serine/threonine-protein kinase STE20 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=STE20 PE=1 SV=1
Length=939
Score = 233 bits (595), Expect = 4e-62, Method: Composition-based stats.
Identities = 62/282 (22%), Positives = 116/282 (41%), Gaps = 25/282 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G G V Y GT VA+K + + P+ + EI +++ H +I+
Sbjct 625 KIGQGASGGV----YTAYEIGTNVSVAIKQMNLEKQPK-KELIINEILVMKGSKHPNIVN 679
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
+ +G+ L ++MEY+ GSL D + + Q+ ++ G+ +LH++ +H
Sbjct 680 FIDSYVLKGD--LWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLH 737
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RD+ + N+LL + +K+ DFG + +E R +W APE + ++
Sbjct 738 RDIKSDNILLSMEGDIKLTDFGFCAQI---NELNLKRTTMVGTPYWMAPEVVSRKEYGPK 794
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
D+WS G+ + E++ + T L IA +L P+
Sbjct 795 VDIWSLGIMIIEMI-EGEPPYLNETPLRALYLIATNGTP------------KLKEPENLS 841
Query 1142 CEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAP 1181
+ + C E R + L+ + + E AP
Sbjct 842 SSLKKFLDWCLCVEPEDRASATELLHDEYITEIAEANSSLAP 883
Score = 185 bits (470), Expect = 1e-46, Method: Composition-based stats.
Identities = 60/300 (20%), Positives = 100/300 (33%), Gaps = 44/300 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L+++ + L +GQG VY + G
Sbjct 607 LNEICSDGDPSTKYANLVKIGQGASGGVY------------------------TAYEIGT 642
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+ V +K ++ +M H ++ V + ++ EY+E G L
Sbjct 643 NVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSL 702
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+ + V ++ S L +L +K ++H ++ NILL+ G I
Sbjct 703 TDVVTH--CILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGD-------I 753
Query 756 KLSDPGVGLGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D G L R V W+APE + +D W G ++E+ +G
Sbjct 754 KLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVS--RKEYGPKVDIWSLGIMIIEMI-EG 810
Query 812 EAPLQSRSPSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
E P + +P + PE L CL EP R S +L D
Sbjct 811 EPPYLNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELLHDEY 870
>sp|Q9FIL7|CRCK1_ARATH Calmodulin-binding receptor-like cytoplasmic
kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CRCK1 PE=1
SV=1
Length=470
Score = 223 bits (568), Expect = 4e-62, Method: Composition-based stats.
Identities = 74/312 (24%), Positives = 127/312 (41%), Gaps = 16/312 (5%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-C 936
P + + +GEG FG V D G +VA+K + +
Sbjct 128 WHQGPVIFSFGELQRATANFSSVHQIGEGGFGTVFKGKLD-----DGTIVAIKRARKNNY 182
Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRH 993
G +K EI L + H +++K G E EK +V+EYV G+LR++L +
Sbjct 183 GKSWLLEFKNEIYTLSKIEHMNLVKLYGFLEHGDEK--VIVVEYVANGNLREHLDGLRGN 240
Query 994 SIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
+ +A+ L A + + YLH IHRD+ A N+L+ N K+ DFG A+ V E
Sbjct 241 RLEMAERLEIAIDVAHALTYLHTYTDSPIIHRDIKASNILITNKLRAKVADFGFARLVSE 300
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFL 1109
+ + P+ L+ ++ SDV+SFGV L E+LT + P K
Sbjct 301 DLGATHISTQVKGSAGYVDPDYLRTFQLTDKSDVYSFGVLLVEILTGRRPIELKRPRKDR 360
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPD-KCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
+ A ++ +++ + R + ++ L C + RP + +
Sbjct 361 LTVKWALRRLKDDEAVLIMDPFLKRNRAAIEVAEKMLRLASECVTPTRATRPAMKGIAEK 420
Query 1169 LKTVHEKYQGQA 1180
L + + +
Sbjct 421 LWAIRREMKETM 432
Score = 197 bits (500), Expect = 4e-53, Method: Composition-based stats.
Identities = 64/332 (19%), Positives = 116/332 (35%), Gaps = 67/332 (20%)
Query 579 LSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
SF + + + +G+G V++G+L
Sbjct 135 FSFGELQRATANFSSVHQIGEGGFGTVFKGKLDDG------------------------- 169
Query 637 LRVVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
V +K ++ L F +S++ H +L ++G G E ++V EYV +G
Sbjct 170 TIVAIKRARKNNYGKSWLLEFKNEIYTLSKIEHMNLVKLYGFLEHGDEKVIVVEYVANGN 229
Query 695 LDVWLRRERGH-VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEG 750
L L RG+ + MA ++ +A +A AL+YL + ++H ++ NIL+ A
Sbjct 230 LREHLDGLRGNRLEMAERLEIAIDVAHALTYLHTYTDSPIIHRDIKASNILITNKLRA-- 287
Query 751 TSPFIKLSDPGVGLGALSR-------EERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
K++D G + ++ P+ L L+ D + FG
Sbjct 288 -----KVADFGFARLVSEDLGATHISTQVKGSAGYVDPDYLRT--FQLTDKSDVYSFGVL 340
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-----SCPQLA-------------TLT 845
L+EI R ++ RL + P L L
Sbjct 341 LVEILTGRRPIELKRPRKDRLTVKWALRRLKDDEAVLIMDPFLKRNRAAIEVAEKMLRLA 400
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
S+C+T RP+ + I L ++ +
Sbjct 401 SECVTPTRATRPAMKGIAEKLWAIRREMKETM 432
>sp|Q54JG7|DST4_DICDI Serine/threonine-protein kinase dst4 OS=Dictyostelium
discoideum OX=44689 GN=dst4 PE=3 SV=1
Length=485
Score = 223 bits (569), Expect = 4e-62, Method: Composition-based stats.
Identities = 77/294 (26%), Positives = 125/294 (43%), Gaps = 33/294 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT-LYHEHIIK 961
+G+G FG V N E+VA+K L+ + + S K+EI IL+ + +I+K
Sbjct 27 IGQGSFGVVCTC----INTVNNEVVAIKFLEMEG--EENSSLKKEITILKNTVRCPYIVK 80
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y GC E +L +VMEY GS+ D + ++ AQ+ QI EG+ YLH+
Sbjct 81 YHGCYIK--ENNLMIVMEYCDGGSILDIMQMCSITLTEAQIAAILYQIVEGLVYLHSNKI 138
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK----E 1075
+HRD+ A NVL++ K+ DFG++ + + +W +PE +
Sbjct 139 LHRDIKAGNVLVNKLGQAKLADFGVSAILVNTGFKQKT---VVGSPYWMSPEVISPPKGS 195
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ +D+WS G+T E+ + PP L + + + L
Sbjct 196 NGYDSKADIWSLGITAIEM-----AESKPPLFNLNPVKVI--------FVIPFRQAPTLE 242
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAPSVFSVC 1187
P E + C EA RP+ +L+ P +K E Q + C
Sbjct 243 VPGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFIKKGKEHSQPTISEMVEQC 296
Score = 196 bits (498), Expect = 1e-52, Method: Composition-based stats.
Identities = 58/325 (18%), Positives = 115/325 (35%), Gaps = 44/325 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
++ L +GQG+ V V V +
Sbjct 14 EEDPEQLFRVLEVIGQGSFGVVCTCINTVNNE------------------------VVAI 49
Query 642 KVLDPSHHDIALAFYETASLMSQ-VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L+ + + + + +++ V ++ HG ++ ++V EY + G + ++
Sbjct 50 KFLEMEGEENS-SLKKEITILKNTVRCPYIVKYHGCYIKENNLMIVMEYCDGGSILDIMQ 108
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ A + Q+ L YL + ++H ++ N+L+ +LG A KL+D
Sbjct 109 MCSITLTEAQIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQA-------KLADF 161
Query 761 GVGL----GALSREERVERIPWLAPECL--PGGANSLSTAMDKWGFGATLLEICFDGEAP 814
GV ++ V W++PE + P G+N + D W G T +E+ + P
Sbjct 162 GVSAILVNTGFKQKTVVGSPYWMSPEVISPPKGSNGYDSKADIWSLGITAIEMAES-KPP 220
Query 815 LQSRSPSEKEHFYQRQH----RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
L + +P + + +P P+ S CL E +RPS +L +
Sbjct 221 LFNLNPVKVIFVIPFRQAPTLEVPGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFIKK 280
Query 871 PHNLADVLTVNPDSPASDPTVFHKR 895
+ ++R
Sbjct 281 GKEHSQPTISEMVEQCIPTMKEYRR 305
>sp|A0A2I0BVG8|CDPK1_PLAFO Calcium-dependent protein kinase 1
OS=Plasmodium falciparum (isolate NF54) OX=5843 GN=PDCK1 PE=1
SV=1
Length=524
Score = 224 bits (572), Expect = 4e-62, Method: Composition-based stats.
Identities = 76/292 (26%), Positives = 117/292 (40%), Gaps = 47/292 (16%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--------------DCGPQHRS 942
K+R LG G +G+V L + GE A+K +K +C +
Sbjct 56 YFKVRKLGSGAYGEVLLCREKHGH---GEK-AIKVIKKSQFDKMKYSITNKIECDDKIHE 111
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLL 1001
EI +L++L H +IIK ED+ K LV E+ G L + + RH
Sbjct 112 EIYNEISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAA 169
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVR 1058
+QI G+ YLH + +HRD+ N+LL+N +KI DFGL+ + ++
Sbjct 170 NIMKQILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKL---- 225
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
D ++ APE L+ K+ DVWS GV LY LL G
Sbjct 226 RDRLGTAYYIAPEVLR-KKYNEKCDVWSCGVILYILLCGYPPF---------------GG 269
Query 1119 MTVLRLTELLERG-ERLPRPD--KCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + +E+G D E L+K + + R T + +
Sbjct 270 QNDQDIIKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALN 321
Score = 181 bits (458), Expect = 4e-47, Method: Composition-based stats.
Identities = 66/382 (17%), Positives = 119/382 (31%), Gaps = 36/382 (9%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ ++ LG G V R + + + + +
Sbjct 54 ESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNK---------IE 104
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
I Y SL+ + H ++ + V +VTE+ E G L + R
Sbjct 105 CDDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQII-NRHKF 163
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ +Q+ S + YL N+VH ++ NILL + + IK+ D G+
Sbjct 164 DECDAANIMKQILSGICYLHKHNIVHRDIKPENILLEN----KHSLLNIKIVDFGLSSFF 219
Query 767 LSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+R+ ++APE L + D W G L I G P ++ +
Sbjct 220 SKDNKLRDRLGTAYYIAPEVLR---KKYNEKCDVWSCGVILY-ILLCGYPPFGGQNDQDI 275
Query 824 EHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
++ + + L LTY+ +R + + L + N +
Sbjct 276 IKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALNSKWIKKYANNINKS 335
Query 879 TVNPDSPASDPTVFHKRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC 936
A + K + L G L + + T K L +
Sbjct 336 DQKTLCGALSNMRKFEGSQKLAQAAILFIGS----KLTTLEERKELTDIF---KKLDKNG 388
Query 937 GPQHRSGWKQE-IDILRTLYHE 957
Q E +ILR+ +E
Sbjct 389 DGQLDKKELIEGYNILRSFKNE 410
>sp|P62343|CDPK1_PLAFK Calcium-dependent protein kinase 1 OS=Plasmodium
falciparum (isolate K1 / Thailand) OX=5839 GN=CDPK1
PE=1 SV=2
Length=524
Score = 224 bits (572), Expect = 4e-62, Method: Composition-based stats.
Identities = 76/292 (26%), Positives = 117/292 (40%), Gaps = 47/292 (16%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--------------DCGPQHRS 942
K+R LG G +G+V L + GE A+K +K +C +
Sbjct 56 YFKVRKLGSGAYGEVLLCREKHGH---GEK-AIKVIKKSQFDKMKYSITNKIECDDKIHE 111
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLL 1001
EI +L++L H +IIK ED+ K LV E+ G L + + RH
Sbjct 112 EIYNEISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAA 169
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVR 1058
+QI G+ YLH + +HRD+ N+LL+N +KI DFGL+ + ++
Sbjct 170 NIMKQILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKL---- 225
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
D ++ APE L+ K+ DVWS GV LY LL G
Sbjct 226 RDRLGTAYYIAPEVLR-KKYNEKCDVWSCGVILYILLCGYPPF---------------GG 269
Query 1119 MTVLRLTELLERG-ERLPRPD--KCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + +E+G D E L+K + + R T + +
Sbjct 270 QNDQDIIKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALN 321
Score = 181 bits (458), Expect = 4e-47, Method: Composition-based stats.
Identities = 66/382 (17%), Positives = 119/382 (31%), Gaps = 36/382 (9%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ ++ LG G V R + + + + +
Sbjct 54 ESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNK---------IE 104
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
I Y SL+ + H ++ + V +VTE+ E G L + R
Sbjct 105 CDDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQII-NRHKF 163
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ +Q+ S + YL N+VH ++ NILL + + IK+ D G+
Sbjct 164 DECDAANIMKQILSGICYLHKHNIVHRDIKPENILLEN----KHSLLNIKIVDFGLSSFF 219
Query 767 LSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+R+ ++APE L + D W G L I G P ++ +
Sbjct 220 SKDNKLRDRLGTAYYIAPEVLR---KKYNEKCDVWSCGVILY-ILLCGYPPFGGQNDQDI 275
Query 824 EHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
++ + + L LTY+ +R + + L + N +
Sbjct 276 IKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALNSKWIKKYANNINKS 335
Query 879 TVNPDSPASDPTVFHKRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC 936
A + K + L G L + + T K L +
Sbjct 336 DQKTLCGALSNMRKFEGSQKLAQAAILFIGS----KLTTLEERKELTDIF---KKLDKNG 388
Query 937 GPQHRSGWKQE-IDILRTLYHE 957
Q E +ILR+ +E
Sbjct 389 DGQLDKKELIEGYNILRSFKNE 410
>sp|P62344|CDPK1_PLAF7 Calcium-dependent protein kinase 1 OS=Plasmodium
falciparum (isolate 3D7) OX=36329 GN=CDPK1 PE=1 SV=2
Length=524
Score = 224 bits (572), Expect = 4e-62, Method: Composition-based stats.
Identities = 76/292 (26%), Positives = 117/292 (40%), Gaps = 47/292 (16%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--------------DCGPQHRS 942
K+R LG G +G+V L + GE A+K +K +C +
Sbjct 56 YFKVRKLGSGAYGEVLLCREKHGH---GEK-AIKVIKKSQFDKMKYSITNKIECDDKIHE 111
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLL 1001
EI +L++L H +IIK ED+ K LV E+ G L + + RH
Sbjct 112 EIYNEISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAA 169
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVR 1058
+QI G+ YLH + +HRD+ N+LL+N +KI DFGL+ + ++
Sbjct 170 NIMKQILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKL---- 225
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
D ++ APE L+ K+ DVWS GV LY LL G
Sbjct 226 RDRLGTAYYIAPEVLR-KKYNEKCDVWSCGVILYILLCGYPPF---------------GG 269
Query 1119 MTVLRLTELLERG-ERLPRPD--KCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + +E+G D E L+K + + R T + +
Sbjct 270 QNDQDIIKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALN 321
Score = 181 bits (458), Expect = 4e-47, Method: Composition-based stats.
Identities = 66/382 (17%), Positives = 119/382 (31%), Gaps = 36/382 (9%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ ++ LG G V R + + + + +
Sbjct 54 ESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNK---------IE 104
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
I Y SL+ + H ++ + V +VTE+ E G L + R
Sbjct 105 CDDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQII-NRHKF 163
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ +Q+ S + YL N+VH ++ NILL + + IK+ D G+
Sbjct 164 DECDAANIMKQILSGICYLHKHNIVHRDIKPENILLEN----KHSLLNIKIVDFGLSSFF 219
Query 767 LSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+R+ ++APE L + D W G L I G P ++ +
Sbjct 220 SKDNKLRDRLGTAYYIAPEVLR---KKYNEKCDVWSCGVILY-ILLCGYPPFGGQNDQDI 275
Query 824 EHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
++ + + L LTY+ +R + + L + N +
Sbjct 276 IKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALNSKWIKKYANNINKS 335
Query 879 TVNPDSPASDPTVFHKRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC 936
A + K + L G L + + T K L +
Sbjct 336 DQKTLCGALSNMRKFEGSQKLAQAAILFIGS----KLTTLEERKELTDIF---KKLDKNG 388
Query 937 GPQHRSGWKQE-IDILRTLYHE 957
Q E +ILR+ +E
Sbjct 389 DGQLDKKELIEGYNILRSFKNE 410
>sp|P41892|CDC7_SCHPO Cell division control protein 7 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=cdc7
PE=1 SV=1
Length=1062
Score = 234 bits (598), Expect = 4e-62, Method: Composition-based stats.
Identities = 79/281 (28%), Positives = 119/281 (42%), Gaps = 28/281 (10%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQE 947
+ LG+G FG V Y N GE VAVK +K + S K E
Sbjct 1 MHNIQASSITLGDCLGKGAFGAV----YRGLNIKNGETVAVKKVKLSKMLKSDLSVIKME 56
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQ 1006
ID+L+ L H +I+KY+G Q SL +++EY GSLR I + L+ Q
Sbjct 57 IDLLKNLDHPNIVKYRGSY--QTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQ 114
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+ +G+ YLH Q IHRD+ N+L D +K+ DFG+A + ++ +
Sbjct 115 VLQGLLYLHNQGVIHRDIKGANILTTKDGTIKLADFGVATKINALEDH-----SVVGSPY 169
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE ++ ASD+WS G T+ ELL +PP L+ +
Sbjct 170 WMAPEVIELVGATTASDIWSVGCTVIELL-----DGNPPYYDLDPTSALFRMV------- 217
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ E P P + C++ + + R L+
Sbjct 218 ---KDEHPPLPSNISSAAKSFLMQCFQKDPNLRIKTRKLLK 255
Score = 207 bits (527), Expect = 2e-53, Method: Composition-based stats.
Identities = 66/297 (22%), Positives = 104/297 (35%), Gaps = 41/297 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
H + IT LG+G VY G G V +
Sbjct 2 HNIQASSITLGDCLGKGAFGAVYRGLNIKNGE------------------------TVAV 37
Query 642 KVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
K + S + L+ + H ++ G ++ EY E+G L +
Sbjct 38 KKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRGSYQTNDSLCIILEYCENGSLRS-I 96
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ G +P + Q+ L YL N+ ++H ++ G NIL + G IKL+D
Sbjct 97 CKNFGKIPENLVALYTFQVLQGLLYLHNQGVIHRDIKGANILTTKDG-------TIKLAD 149
Query 760 PGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
GV + AL V W+APE + +TA D W G T++E+ DG P
Sbjct 150 FGVATKINALEDHSVVGSPYWMAPEVIELVGA--TTASDIWSVGCTVIELL-DGNPPYYD 206
Query 818 RSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
P+ + LP + QC +P R R +L+ +
Sbjct 207 LDPTSALFRMVKDEHPPLPSNISSAAKSFLMQCFQKDPNLRIKTRKLLKHPWVIMNQ 263
>sp|Q04982|BRAF_CHICK Serine/threonine-protein kinase B-raf OS=Gallus
gallus OX=9031 GN=BRAF PE=1 SV=2
Length=766
Score = 230 bits (587), Expect = 4e-62, Method: Composition-based stats.
Identities = 76/306 (25%), Positives = 130/306 (42%), Gaps = 31/306 (10%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+ + +SD + + +G G FG V + VAVK L
Sbjct 435 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-------DVAVKMLNV 487
Query 935 DC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991
PQ +K E+ +LR H +I+ + G + L +V ++ SL +L
Sbjct 488 TAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY---STKPQLAIVTQWCEGSSLYHHLHII 544
Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
+ +L+ A+Q +GM YLHA+ IHRDL + N+ L D VKIGDFGLA
Sbjct 545 ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRW 604
Query 1052 HEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQ--SPPT 1106
++ E + W APE ++ + + + SDV++FG+ LYEL+T +
Sbjct 605 SGSHQF-EQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRD 663
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ + ++G + ++ CP + LM C + + RP F ++
Sbjct 664 QIIFMVGRGYLSPDLSKVR------------SNCPKAMKRLMAECLKKKRDERPLFPQIL 711
Query 1167 PILKTV 1172
++ +
Sbjct 712 ASIELL 717
Score = 225 bits (573), Expect = 3e-60, Method: Composition-based stats.
Identities = 71/378 (19%), Positives = 130/378 (34%), Gaps = 57/378 (15%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSF-HRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
P P R +TL S + +IT +G G+ VY+G+ +
Sbjct 420 PGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD 479
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSHTH 669
V +K+L+ + AF ++ + H +
Sbjct 480 ---------------------------VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVN 512
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729
+ G + P+ +VT++ E L L M + +A+Q A + YL K+
Sbjct 513 ILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKS 571
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPEC 783
++H ++ NI L +K+ D G+ G+ E+ I W+APE
Sbjct 572 IIHRDLKSNNIFLHE-------DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEV 624
Query 784 LPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP------ 836
+ N S D + FG L E+ G+ P + + ++ F + L
Sbjct 625 IRMQDKNPYSFQSDVYAFGIVLYELM-TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRS 683
Query 837 SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL----TRLQPHNLADVLTVNPDSPASDPTV 891
+CP+ + L ++CL + +RP F IL + L + + +
Sbjct 684 NCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDF 743
Query 892 FHKRYLKKIRDLGEGHFG 909
+ G +G
Sbjct 744 SLYACASPKTPIQAGGYG 761
>sp|C0LGD9|Y1756_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g07560 OS=Arabidopsis thaliana OX=3702
GN=At1g07560 PE=1 SV=1
Length=871
Score = 232 bits (592), Expect = 4e-62, Method: Composition-based stats.
Identities = 68/273 (25%), Positives = 118/273 (43%), Gaps = 14/273 (5%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V + T E VAVK L Q +K E+++L +YH +++
Sbjct 576 LGKGGFGMVYHGYINGT-----EEVAVKLLSP-SSAQGYKEFKTEVELLLRVYHTNLVSL 629
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLH---AQH 1018
G C+++ L L+ +Y+ G L+ + SI L A G+ YLH
Sbjct 630 VGYCDEKDH--LALIYQYMVNGDLKKHFSGSSIISWVDRLNIAVDAASGLEYLHIGCKPL 687
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRD+ + N+LLD+ K+ DFGL+++ P G E + V + E + +
Sbjct 688 IVHRDVKSSNILLDDQLQAKLADFGLSRSFPIGDESH-VSTLVAGTFGYLDHEYYQTNRL 746
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SDV+SFGV L E++T+ + + +T ++ +++ +
Sbjct 747 SEKSDVYSFGVVLLEIITNKPVIDH-NRDMPHIAEWVKLMLTRGDISNIMDPKLQGVYDS 805
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ L C + RP +++ LK
Sbjct 806 GSAWKALELAMTCVNPSSLKRPNMSHVVHELKE 838
Score = 200 bits (509), Expect = 1e-51, Method: Composition-based stats.
Identities = 63/312 (20%), Positives = 101/312 (32%), Gaps = 59/312 (19%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+ ++ V LG+G VY G +
Sbjct 558 KRYTYAEVLAMTKKFERVLGKGGFGMVYHGYINGTE------------------------ 593
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K+L PS F L+ +V HT+L + G C ++ +Y+ +G L
Sbjct 594 -EVAVKLLSPSSAQGYKEFKTEVELLLRVYHTNLVSLVGYCDEKDHLALIYQYMVNGDLK 652
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSP 753
+ ++ +A AS L YL +VH +V NILL A
Sbjct 653 KH-FSGSSIISWVDRLNIAVDAASGLEYLHIGCKPLIVHRDVKSSNILLDDQLQA----- 706
Query 754 FIKLSDPGVGLG-ALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
KL+D G+ + E V +L E N LS D + FG LLEI
Sbjct 707 --KLADFGLSRSFPIGDESHVSTLVAGTFGYLDHEYYQT--NRLSEKSDVYSFGVVLLEI 762
Query 808 CFDGEAPLQSRSP---SEKEHFYQRQHRLPEPSCPQL------------ATLTSQCLTYE 852
+ +R +E + + P+L L C+
Sbjct 763 ITNKPVIDHNRDMPHIAEWVKLMLTRGDISNIMDPKLQGVYDSGSAWKALELAMTCVNPS 822
Query 853 PTQRPSFRTILR 864
+RP+ ++
Sbjct 823 SLKRPNMSHVVH 834
>sp|O80939|LRK41_ARATH L-type lectin-domain containing receptor
kinase IV.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK41 PE=2
SV=1
Length=675
Score = 228 bits (582), Expect = 4e-62, Method: Composition-based stats.
Identities = 73/276 (26%), Positives = 116/276 (42%), Gaps = 17/276 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V Y GT +AVK + + Q + EI + + H +++
Sbjct 353 LGTGGFGSV----YKGVMPGTKLEIAVKRVSHE-SRQGMKEFVAEIVSIGRMSHRNLVPL 407
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018
G C +GE L LV +Y+P GSL YL P ++ Q + + G+ YLH +
Sbjct 408 LGYCRRRGE--LLLVYDYMPNGSLDKYLYNTPEVTLNWKQRIKVILGVASGLFYLHEEWE 465
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ A NVLLD + ++GDFGLA+ G + + + APE +
Sbjct 466 QVVIHRDVKASNVLLDGELNGRLGDFGLARLYDHGSDPQTTH--VVGTLGYLAPEHTRTG 523
Query 1077 KFYYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ A+DV++FG L E+ Q + L+ G + +
Sbjct 524 RATMATDVFAFGAFLLEVACGRRPIEFQQETDETFLLVDWVFGLWNKGDILAAKDPNMGS 583
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+K V L C ++ RP+ ++ L+
Sbjct 584 ECDEKEVEMVLKLGLLCSHSDPRARPSMRQVLHYLR 619
Score = 204 bits (519), Expect = 8e-54, Method: Composition-based stats.
Identities = 63/308 (20%), Positives = 104/308 (34%), Gaps = 60/308 (19%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
K + LG G +VY+G + G +L + +K +
Sbjct 343 ATKGFKEKGLLGTGGFGSVYKGVM------------------------PGTKLEIAVKRV 378
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ER 703
F + ++SH +L + G C R E ++V +Y+ +G LD +L
Sbjct 379 SHESRQGMKEFVAEIVSIGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNTPE 438
Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ ++ V +AS L YL + ++H +V N+LL +L D
Sbjct 439 VTLNWKQRIKVILGVASGLFYLHEEWEQVVIHRDVKASNVLLD-------GELNGRLGDF 491
Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ V + +LAPE G +++T D + FGA LLE+
Sbjct 492 GLARLYDHGSDPQTTHVVGTLGYLAPEHTRTGRATMAT--DVFAFGAFLLEVACGRRPIE 549
Query 816 QSRSPSEKEHFYQRQHRLP------------------EPSCPQLATLTSQCLTYEPTQRP 857
+ E L E + L C +P RP
Sbjct 550 FQQETDETFLLVDWVFGLWNKGDILAAKDPNMGSECDEKEVEMVLKLGLLCSHSDPRARP 609
Query 858 SFRTILRD 865
S R +L
Sbjct 610 SMRQVLHY 617
>sp|Q9CAD5|YODA_ARATH Mitogen-activated protein kinase kinase
kinase YODA OS=Arabidopsis thaliana OX=3702 GN=YDA PE=1 SV=1
Length=883
Score = 232 bits (592), Expect = 4e-62, Method: Composition-based stats.
Identities = 88/312 (28%), Positives = 134/312 (43%), Gaps = 30/312 (10%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
I ++ A +V ++ TV KK R LG G FG V L N
Sbjct 365 ISNTCPFSPTYSAATSPSVPRSPARAEATVSPGSRWKKGRLLGMGSFGHVYLGF----NS 420
Query 922 GTGEMVAVKALKA-DCGPQHRSGWKQ---EIDILRTLYHEHIIKYKGCCEDQGEKSLQLV 977
+GEM A+K + P+ R +Q EI +L L H++I++Y G + + L +
Sbjct 421 ESGEMCAMKEVTLCSDDPKSRESAQQLGQEISVLSRLRHQNIVQYYGS--ETVDDKLYIY 478
Query 978 MEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036
+EYV GS+ L + G + + QQI G+AYLHA++ +HRD+ N+L+D
Sbjct 479 LEYVSGGSIYKLLQEYGQFGENAIRNYTQQILSGLAYLHAKNTVHRDIKGANILVDPHGR 538
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELL 1095
VK+ DFG+AK + +W APE +K A D+WS G T+ E+
Sbjct 539 VKVADFGMAKHI----TAQSGPLSFKGSPYWMAPEVIKNSNGSNLAVDIWSLGCTVLEMA 594
Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155
T PP E V + ++ E PD E ++ C +
Sbjct 595 T-----TKPPWSQYE---------GVPAMFKIGNSKELPDIPDHLSEEGKDFVRKCLQRN 640
Query 1156 ASFRPTFENLIP 1167
+ RPT L+
Sbjct 641 PANRPTAAQLLD 652
Score = 191 bits (486), Expect = 1e-48, Method: Composition-based stats.
Identities = 74/349 (21%), Positives = 117/349 (34%), Gaps = 40/349 (11%)
Query 539 RAGDDCFSLRRCCLPQPGETSNLIIMR---GARASPRTLNLSQLSFHRVDQ-KEITQLSH 594
R D+ R LP P SN A SP + V +
Sbjct 347 RLDDNRQQSHRLPLP-PLLISNTCPFSPTYSAATSPSVPRSPARAEATVSPGSRWKKGRL 405
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LG G+ +VY G G + V L DP + A
Sbjct 406 LGMGSFGHVYLGFNSESGEMCAMK-------------------EVTLCSDDPKSRESAQQ 446
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714
+ S++S++ H ++ +G + + EYV G + L+ E G
Sbjct 447 LGQEISVLSRLRHQNIVQYYGSETVDDKLYIYLEYVSGGSIYKLLQ-EYGQFGENAIRNY 505
Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---E 771
QQ+ S L+YL KN VH ++ G NIL+ G +K++D G+ ++
Sbjct 506 TQQILSGLAYLHAKNTVHRDIKGANILVDPHGR-------VKVADFGMAKHITAQSGPLS 558
Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
W+APE + S + A+D W G T+LE+ + P
Sbjct 559 FKGSPYWMAPEVIKNSNGS-NLAVDIWSLGCTVLEMATT-KPPWSQYEGVPAMFKIGNSK 616
Query 832 RL---PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
L P+ + +CL P RP+ +L +
Sbjct 617 ELPDIPDHLSEEGKDFVRKCLQRNPANRPTAAQLLDHAFVRNVMPMERP 665
>sp|Q8CIP4|MARK4_MOUSE MAP/microtubule affinity-regulating kinase
4 OS=Mus musculus OX=10090 GN=Mark4 PE=1 SV=1
Length=752
Score = 230 bits (586), Expect = 4e-62, Method: Composition-based stats.
Identities = 77/292 (26%), Positives = 126/292 (43%), Gaps = 30/292 (10%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEID 949
H + +R +G+G+F KV L + TG VA+K + K P +E+
Sbjct 53 QPHVGNYRLLRTIGKGNFAKVKL----ARHILTGREVAIKIIDKTQLNPSSLQKLFREVR 108
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQIC 1008
I++ L H +I+K E EK+L LVMEY G + DYL H + + +QI
Sbjct 109 IMKGLNHPNIVKLFEVIE--TEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIV 166
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+ Y H ++ +HRDL A N+LLD + +KI DFG + G + + +
Sbjct 167 SAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKL----DTFCGSPPYA 222
Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + K+ D+WS GV LY L++ + L E
Sbjct 223 APELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFD---------------GHNLKELRER 267
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+ RG + P + +++ + R T E ++ K ++ Y+G+
Sbjct 268 VLRG-KYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKD-KWINIGYEGE 317
Score = 188 bits (477), Expect = 4e-48, Method: Composition-based stats.
Identities = 53/286 (19%), Positives = 96/286 (34%), Gaps = 40/286 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
L +G+G V R + G V +K++D +
Sbjct 58 NYRLLRTIGKGNFAKVKLARHILTGR------------------------EVAIKIIDKT 93
Query 648 HHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ + + +M ++H ++ + V +V EY G + +L G
Sbjct 94 QLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSH-GR 152
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763
+ +Q+ SA+ Y KN+VH ++ N+LL IK++D G
Sbjct 153 MKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD-------AEANIKIADFGFSNE 205
Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ P+ APE G +D W G L + G P + E
Sbjct 206 FTLGSKLDTFCGSPPYAAPELFQGKKYD-GPEVDIWSLGVILYTLVS-GSLPFDGHNLKE 263
Query 823 KEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
R +R+P ++ + L P +R + I++D
Sbjct 264 LRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKW 309
>sp|Q96L34|MARK4_HUMAN MAP/microtubule affinity-regulating kinase
4 OS=Homo sapiens OX=9606 GN=MARK4 PE=1 SV=1
Length=752
Score = 230 bits (586), Expect = 4e-62, Method: Composition-based stats.
Identities = 77/292 (26%), Positives = 126/292 (43%), Gaps = 30/292 (10%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEID 949
H + +R +G+G+F KV L + TG VA+K + K P +E+
Sbjct 53 QPHVGNYRLLRTIGKGNFAKVKL----ARHILTGREVAIKIIDKTQLNPSSLQKLFREVR 108
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQIC 1008
I++ L H +I+K E EK+L LVMEY G + DYL H + + +QI
Sbjct 109 IMKGLNHPNIVKLFEVIE--TEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIV 166
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+ Y H ++ +HRDL A N+LLD + +KI DFG + G + + +
Sbjct 167 SAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKL----DTFCGSPPYA 222
Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + K+ D+WS GV LY L++ + L E
Sbjct 223 APELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFD---------------GHNLKELRER 267
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+ RG + P + +++ + R T E ++ K ++ Y+G+
Sbjct 268 VLRG-KYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKD-KWINIGYEGE 317
Score = 188 bits (477), Expect = 4e-48, Method: Composition-based stats.
Identities = 53/286 (19%), Positives = 96/286 (34%), Gaps = 40/286 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
L +G+G V R + G V +K++D +
Sbjct 58 NYRLLRTIGKGNFAKVKLARHILTGR------------------------EVAIKIIDKT 93
Query 648 HHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ + + +M ++H ++ + V +V EY G + +L G
Sbjct 94 QLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSH-GR 152
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763
+ +Q+ SA+ Y KN+VH ++ N+LL IK++D G
Sbjct 153 MKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD-------AEANIKIADFGFSNE 205
Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ P+ APE G +D W G L + G P + E
Sbjct 206 FTLGSKLDTFCGSPPYAAPELFQGKKYD-GPEVDIWSLGVILYTLVS-GSLPFDGHNLKE 263
Query 823 KEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
R +R+P ++ + L P +R + I++D
Sbjct 264 LRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKW 309
>sp|C0LGF5|RGI5_ARATH LRR receptor-like serine/threonine-protein
kinase RGI5 OS=Arabidopsis thaliana OX=3702 GN=RGI5 PE=1
SV=2
Length=1072
Score = 234 bits (598), Expect = 4e-62, Method: Composition-based stats.
Identities = 73/313 (23%), Positives = 120/313 (38%), Gaps = 19/313 (6%)
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932
+ + T P L +G+G G V G++VAVK L
Sbjct 748 DFSYPWTFIPFQKLGITVNNIVTSLTDENVIGKGCSGIVYKA-----EIPNGDIVAVKKL 802
Query 933 -----KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
+ G + EI IL + H +I+K G C ++ K L+ Y P G+L+
Sbjct 803 WKTKDNNEEGESTIDSFAAEIQILGNIRHRNIVKLLGYCSNKSVK--LLLYNYFPNGNLQ 860
Query 988 DYLP-RHSIGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFG 1043
L ++ A +G+AYLH +HRD+ N+LLD+ + DFG
Sbjct 861 QLLQGNRNLDWETRYKIAIGAAQGLAYLHHDCVPAILHRDVKCNNILLDSKYEAILADFG 920
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
LAK + Y+ + APE SDV+S+GV L E+L+ + +
Sbjct 921 LAKLMMNSPNYHNAMSRVAGSYGYIAPEYGYTMNITEKSDVYSYGVVLLEILSGRSAVEP 980
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH---LMKNCWETEASFRP 1160
L ++ + +M + + PD+ E+ + C RP
Sbjct 981 QIGDGLHIVEWVKKKMGTFEPALSVLDVKLQGLPDQIVQEMLQTLGIAMFCVNPSPVERP 1040
Query 1161 TFENLIPILKTVH 1173
T + ++ +L V
Sbjct 1041 TMKEVVTLLMEVK 1053
Score = 178 bits (452), Expect = 3e-44, Method: Composition-based stats.
Identities = 52/318 (16%), Positives = 106/318 (33%), Gaps = 70/318 (22%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---- 644
+T + +G+G VY+ + V +K L
Sbjct 772 LTDENVIGKGCSGIVYKAEIPNGDI-------------------------VAVKKLWKTK 806
Query 645 --DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+ +F ++ + H ++ + G C +++ Y +G L L+
Sbjct 807 DNNEEGESTIDSFAAEIQILGNIRHRNIVKLLGYCSNKSVKLLLYNYFPNGNLQQLLQGN 866
Query 703 RGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R ++ + +A A L+YL + ++H +V NILL A L+D
Sbjct 867 R-NLDWETRYKIAIGAAQGLAYLHHDCVPAILHRDVKCNNILLDSKYEAI-------LAD 918
Query 760 PGVGLGALSREER-------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
G+ ++ ++APE G +++ D + +G LLEI
Sbjct 919 FGLAKLMMNSPNYHNAMSRVAGSYGYIAPEY--GYTMNITEKSDVYSYGVVLLEILSGRS 976
Query 813 A--PLQSRSPSEKEHFYQRQHR--------------LPEPSCPQLAT---LTSQCLTYEP 853
A P E ++ LP+ ++ + C+ P
Sbjct 977 AVEPQIGDGLHIVEWVKKKMGTFEPALSVLDVKLQGLPDQIVQEMLQTLGIAMFCVNPSP 1036
Query 854 TQRPSFRTILRDLTRLQP 871
+RP+ + ++ L ++
Sbjct 1037 VERPTMKEVVTLLMEVKC 1054
>sp|Q6PWX2|HOG1_BEABA Mitogen-activated protein kinase HOG1 OS=Beauveria
bassiana OX=176275 GN=HOG1 PE=3 SV=1
Length=358
Score = 219 bits (558), Expect = 4e-62, Method: Composition-based stats.
Identities = 67/284 (24%), Positives = 108/284 (38%), Gaps = 29/284 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VAVK + K P +E+ +L+ L HE++
Sbjct 24 QPVGMGAFGLVC----SARDQLTNQNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENV 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLDGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L + ER P + LM+ + R T +
Sbjct 252 SLPKRERQPLRNKFRNADDSAIDLMERMLVFDPKKRITAAEALS 295
Score = 131 bits (330), Expect = 9e-32, Method: Composition-based stats.
Identities = 38/231 (16%), Positives = 75/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E D + M + RD+ V +K ++ P +A Y
Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAVKKIMKPFSTPVLAKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ DG+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-DGKPLFPGKDHVNQFSI 225
>sp|Q5XIT0|CDKL2_RAT Cyclin-dependent kinase-like 2 OS=Rattus
norvegicus OX=10116 GN=Cdkl2 PE=2 SV=1
Length=507
Score = 224 bits (571), Expect = 4e-62, Method: Composition-based stats.
Identities = 74/285 (26%), Positives = 122/285 (43%), Gaps = 29/285 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG +G V N +G +VA+K L++D + +EI +L+ L HE+++
Sbjct 10 VGEGSYGMVM----KCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
C + +K LV E+V L D L + + + + QI G+ + H+ + I
Sbjct 66 LLEVC--KKKKRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFCHSHNII 123
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFY 1079
HRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L K+
Sbjct 124 HRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVKYG 180
Query 1080 YASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
A D+W+ G + E+L +S + +G + L + G RL
Sbjct 181 KAVDIWAIGCLVIEMLMGQPLFPGESDIDQLHHIMTCLGNLIPRHQELFYKNPVFAGVRL 240
Query 1135 P------------RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P R K P V L K C + RP +L+
Sbjct 241 PEIKDIEAEPLESRYPKLPEVVISLAKKCLHIDPDKRPLCADLLH 285
Score = 163 bits (412), Expect = 3e-41, Method: Composition-based stats.
Identities = 63/407 (15%), Positives = 122/407 (30%), Gaps = 85/407 (21%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-L 644
++ L +G+G+ V + R + G V +K L
Sbjct 1 MEKYENLGLVGEGSYGMVMKCRNKDSGR------------------------IVAIKKFL 36
Query 645 DPSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ + L+ Q+ H +L + VC + +V E+V+H LD L+
Sbjct 37 ESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDD-LKLFP 95
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ Q+ + + + + N++H ++ NIL+++ G+ +KL D G
Sbjct 96 NGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFA 148
Query 764 LGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ + V + APE L G A+D W G ++E+
Sbjct 149 RTLAAPGEVYTDYVATRWYRAPELLV-GDVKYGKAVDIWAIGCLVIEMLMGQPLFPGESD 207
Query 820 PSEKEHFY-------------------QRQHRLPEPS--------------CPQLATLTS 846
+ H RLPE + +L
Sbjct 208 IDQLHHIMTCLGNLIPRHQELFYKNPVFAGVRLPEIKDIEAEPLESRYPKLPEVVISLAK 267
Query 847 QCLTYEPTQRP-SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
+CL +P +RP + D ++ + + + + +
Sbjct 268 KCLHIDPDKRPLCADLLHHDFFQMDGFAERFSQELQLKIEKDARNNSLPKKFQIRKKEKD 327
Query 906 GHFGK------VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
G+ V DP + K LK ++
Sbjct 328 DALGEERKTLVVQDTNADPKTKDS------KVLKVKGSKIDVEKTEK 368
>sp|P93749|Y2197_ARATH Probable protein kinase At2g41970 OS=Arabidopsis
thaliana OX=3702 GN=At2g41970 PE=2 SV=1
Length=365
Score = 219 bits (559), Expect = 5e-62, Method: Composition-based stats.
Identities = 69/284 (24%), Positives = 123/284 (43%), Gaps = 23/284 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG +G+V + GE VA+K L A + S + ++ ++ L H+H ++
Sbjct 79 IGEGSYGRVFCGKFK------GEAVAIKKLDASSSEEPDSDFTSQLSVVSRLKHDHFVEL 132
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------IGLAQLLLFAQQICEGMA 1012
G C + + L+ ++ GSL D L + Q + A +G+
Sbjct 133 LGYCLEANNR--ILIYQFATKGSLHDVLHGRKGVQGAEPGPVLNWNQRVKIAYGAAKGLE 190
Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+LH + +HRD+ + NVLL +D + K+ DF L A + ++A
Sbjct 191 FLHEKVQPPIVHRDVRSSNVLLFDDFVAKMADFNLTNASSDTAARLH-STRVLGTFGYHA 249
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE + SDV+SFGV L ELLT + P L+ A +++ ++ + +
Sbjct 250 PEYAMTGQITQKSDVYSFGVVLLELLTGRKPVDHTMPKGQQSLVTWATPRLSEDKVKQCI 309
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ P K ++ + C + EA FRP ++ L+ +
Sbjct 310 DPKLNNDFPPKAVAKLAAVAALCVQYEADFRPNMTIVVKALQPL 353
Score = 182 bits (461), Expect = 5e-49, Method: Composition-based stats.
Identities = 52/290 (18%), Positives = 100/290 (34%), Gaps = 55/290 (19%)
Query 566 GARASPRTLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
GA A + + ++ +++ + +G+G+ V+ G+ + E
Sbjct 48 GAPAKVLPIEIPSVALDELNRMAGNFGNKALIGEGSYGRVFCGKFKGE------------ 95
Query 624 EDPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
V +K LD S + F S++S++ H H + G C+
Sbjct 96 --------------AVAIKKLDASSSEEPDSDFTSQLSVVSRLKHDHFVELLGYCLEANN 141
Query 683 NIMVTEYVEHGPLDVWLRRERG--------HVPMAWKMVVAQQLASALSYLENK---NLV 731
I++ ++ G L L +G + ++ +A A L +L K +V
Sbjct 142 RILIYQFATKGSLHDVLHGRKGVQGAEPGPVLNWNQRVKIAYGAAKGLEFLHEKVQPPIV 201
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGALSREERVERIPWLAPECLP 785
H +V N+LL K++D + L + + APE
Sbjct 202 HRDVRSSNVLL-------FDDFVAKMADFNLTNASSDTAARLHSTRVLGTFGYHAPEYAM 254
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
G ++ D + FG LLE+ + + ++ RL E
Sbjct 255 TG--QITQKSDVYSFGVVLLELLTGRKPVDHTMPKGQQSLVTWATPRLSE 302
>sp|Q9JI10|STK3_MOUSE Serine/threonine-protein kinase 3 OS=Mus
musculus OX=10090 GN=Stk3 PE=1 SV=1
Length=497
Score = 224 bits (570), Expect = 5e-62, Method: Composition-based stats.
Identities = 64/268 (24%), Positives = 110/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V + + +G++VA+K + + Q +EI I++ +++K
Sbjct 32 KLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQ---EIIKEISIMQQCDSPYVVK 84
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ + +G+ YLH
Sbjct 85 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRK 142
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 143 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 199
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 200 CVADIWSLGITSIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 246
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ +K C R T L+
Sbjct 247 WSDDFTDFVKKCLVKSPEQRATATQLLQ 274
Score = 199 bits (505), Expect = 2e-53, Method: Composition-based stats.
Identities = 56/307 (18%), Positives = 99/307 (32%), Gaps = 44/307 (14%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
+ + LS+ S + ++ L LG+G+ +V++ + G
Sbjct 7 SKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQ--------------- 51
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
V +K + + S+M Q ++ +G + + +V E
Sbjct 52 ---------VVAIKQVPVESD--LQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVME 100
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
Y G + +R + + + L YL +H ++ NILL G
Sbjct 101 YCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-- 158
Query 749 EGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
KL+D GV R + W+APE + + D W G T
Sbjct 159 -----HAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITS 211
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
+E+ +G+ P P R PE +CL P QR +
Sbjct 212 IEMA-EGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATAT 270
Query 861 TILRDLT 867
+L+
Sbjct 271 QLLQHPF 277
>sp|O88643|PAK1_MOUSE Serine/threonine-protein kinase PAK 1 OS=Mus
musculus OX=10090 GN=Pak1 PE=1 SV=1
Length=545
Score = 225 bits (573), Expect = 5e-62, Method: Composition-based stats.
Identities = 72/370 (19%), Positives = 132/370 (36%), Gaps = 25/370 (7%)
Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
P+ + P + Y R P P P + + ++ + R+ + +
Sbjct 187 PPVIAPRPEHTKSVYTRSVIEPLPVTPT-RDVATSPISPTENNTTPPDALTRNTEKQKKK 245
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932
+ + K+ +G+G G V Y + TG+ VA+K +
Sbjct 246 PKMSDEEILEKLRSIVSVGDPKKKYTPFEKIGQGASGTV----YTAMDVATGQEVAIKQM 301
Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992
P+ + EI ++R + +I+ Y E L +VMEY+ GSL D +
Sbjct 302 NLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTE 358
Query 993 HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
+ Q+ ++ + + +LH+ IHRD+ + N+LL D VK+ DFG +
Sbjct 359 TCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITP-- 416
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
R +W APE + + D+WS G+ E++ PP +
Sbjct 417 -EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI-----EGEPPYLNENPL 470
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP-ILKT 1171
T L P+K ++ C E + R + + L+
Sbjct 471 RALYLIATNGT--------PELQNPEKLSAIFRDFLQCCLEMDVEKRGSAKELLQHQFLK 522
Query 1172 VHEKYQGQAP 1181
+ + P
Sbjct 523 IAKPLSSLTP 532
Score = 179 bits (455), Expect = 2e-46, Method: Composition-based stats.
Identities = 54/291 (19%), Positives = 94/291 (32%), Gaps = 44/291 (15%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+K+ T +GQG VY D V +K +
Sbjct 266 PKKKYTPFEKIGQGASGTVY------------------------TAMDVATGQEVAIKQM 301
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ +M + + ++ + G E +V EY+ G L +
Sbjct 302 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 359
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ V ++ AL +L + ++H ++ NILL G +KL+D G
Sbjct 360 CMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 412
Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
R V W+APE + A +D W G +E+ +GE P + +P
Sbjct 413 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMI-EGEPPYLNENP 469
Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ PE CL + +R S + +L+
Sbjct 470 LRALYLIATNGTPELQNPEKLSAIFRDFLQCCLEMDVEKRGSAKELLQHQF 520
>sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo
sapiens OX=9606 GN=BRAF PE=1 SV=4
Length=766
Score = 230 bits (586), Expect = 5e-62, Method: Composition-based stats.
Identities = 76/306 (25%), Positives = 130/306 (42%), Gaps = 31/306 (10%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+ + +SD + + +G G FG V + VAVK L
Sbjct 435 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-------DVAVKMLNV 487
Query 935 DC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991
PQ +K E+ +LR H +I+ + G + L +V ++ SL +L
Sbjct 488 TAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY---STKPQLAIVTQWCEGSSLYHHLHII 544
Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
+ +L+ A+Q +GM YLHA+ IHRDL + N+ L D VKIGDFGLA
Sbjct 545 ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRW 604
Query 1052 HEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQ--SPPT 1106
++ E + W APE ++ + + + SDV++FG+ LYEL+T +
Sbjct 605 SGSHQF-EQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRD 663
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ + ++G + ++ CP + LM C + + RP F ++
Sbjct 664 QIIFMVGRGYLSPDLSKVR------------SNCPKAMKRLMAECLKKKRDERPLFPQIL 711
Query 1167 PILKTV 1172
++ +
Sbjct 712 ASIELL 717
Score = 224 bits (572), Expect = 4e-60, Method: Composition-based stats.
Identities = 71/378 (19%), Positives = 130/378 (34%), Gaps = 57/378 (15%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSF-HRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
P P R +TL S + +IT +G G+ VY+G+ +
Sbjct 420 PGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD 479
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSHTH 669
V +K+L+ + AF ++ + H +
Sbjct 480 ---------------------------VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVN 512
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729
+ G + P+ +VT++ E L L M + +A+Q A + YL K+
Sbjct 513 ILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKS 571
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPEC 783
++H ++ NI L +K+ D G+ G+ E+ I W+APE
Sbjct 572 IIHRDLKSNNIFLHE-------DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEV 624
Query 784 LPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP------ 836
+ N S D + FG L E+ G+ P + + ++ F + L
Sbjct 625 IRMQDKNPYSFQSDVYAFGIVLYELM-TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRS 683
Query 837 SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL----TRLQPHNLADVLTVNPDSPASDPTV 891
+CP+ + L ++CL + +RP F IL + L + + +
Sbjct 684 NCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDF 743
Query 892 FHKRYLKKIRDLGEGHFG 909
+ G +G
Sbjct 744 SLYACASPKTPIQAGGYG 761
>sp|Q5RD00|AAPK2_PONAB 5'-AMP-activated protein kinase catalytic
subunit alpha-2 OS=Pongo abelii OX=9601 GN=PRKAA2 PE=2 SV=1
Length=552
Score = 225 bits (573), Expect = 5e-62, Method: Composition-based stats.
Identities = 77/274 (28%), Positives = 106/274 (39%), Gaps = 30/274 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953
+ LG G FGKV + + TG VAVK L K+EI L+
Sbjct 15 HYVLGDTLGVGTFGKVKIGEHQ----LTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012
H HIIK + +VMEYV G L DY+ +H + + QQI +
Sbjct 71 FRHPHIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE
Sbjct 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNIMSDGE---FLRTSCGSPN-YAAPEV 184
Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + D+WS GV LY LL L RG
Sbjct 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLF----------------KKIRG 228
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P+ V L+ + + + R T +++
Sbjct 229 GVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDI 262
Score = 179 bits (454), Expect = 2e-46, Method: Composition-based stats.
Identities = 58/298 (19%), Positives = 96/298 (32%), Gaps = 39/298 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
Q RV LG GT V G ++ G
Sbjct 4 KQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGH----------------------- 40
Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+V +K+L+ D+ + H H+ ++ V + MV EYV G
Sbjct 41 -KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGG 99
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L ++ + G V + QQ+ SA+ Y +VH ++ N+LL
Sbjct 100 ELFDYICKH-GRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLD-------AHM 151
Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ E + APE + G + +D W G L +
Sbjct 152 NAKIADFGLSNIMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSCGVILYALLCG 210
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
P+ + +PE +ATL L +P +R + + I
Sbjct 211 TLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWF 268
>sp|Q54TA3|MRKC_DICDI Probable serine/threonine-protein kinase
MARK-C OS=Dictyostelium discoideum OX=44689 GN=mrkC PE=3 SV=1
Length=773
Score = 230 bits (587), Expect = 5e-62, Method: Composition-based stats.
Identities = 79/299 (26%), Positives = 130/299 (43%), Gaps = 28/299 (9%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
++ + + H + + LG G FGKV L TN T E VA+K
Sbjct 20 NNHHQFNNGGDIIPKKKKNRIMHVGSYEVGKTLGNGTFGKVKLG----TNICTKENVAIK 75
Query 931 ALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK-SLQLVMEYVPLGSLRD 988
+K + + + +EIDI++ L H +I+K + + E+ + L++EYV G L D
Sbjct 76 FIKNNKLSGKQKETCFREIDIMKLLDHPNIVKLLDVVDKREEEGTTYLIVEYVSGGELFD 135
Query 989 YL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
Y+ R I + F +Q+ + Y HA +HRDL N+LLD++ +KI DFGL+
Sbjct 136 YIVAREYIKEKEARKFFRQMISAIEYCHANLIVHRDLKPENLLLDSNGDIKISDFGLSNN 195
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPT 1106
+ G ++ E + APE LK K+ D+WS GV +Y +L +
Sbjct 196 IQPG----KLLESFCGSPLYAAPEILKAEKYLGPPVDIWSLGVIMYAVLCGNLPWE---- 247
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
G +Q +++ + E P E H+++ R T + L
Sbjct 248 ------GDSQAEISFNSVHGNYED------PTHLSAEAVHILRRMIVPNPKDRATIQEL 294
Score = 169 bits (429), Expect = 5e-42, Method: Composition-based stats.
Identities = 49/314 (16%), Positives = 94/314 (30%), Gaps = 43/314 (14%)
Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HH 649
LG GT V G + + V +K + +
Sbjct 49 GKTLGNGTFGKVKLG------------------------TNICTKENVAIKFIKNNKLSG 84
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVC---VRGPENIMVTEYVEHGPLDVWLRRERGHV 706
+ +M + H ++ + V ++ EYV G L ++ R ++
Sbjct 85 KQKETCFREIDIMKLLDHPNIVKLLDVVDKREEEGTTYLIVEYVSGGELFDYI-VAREYI 143
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+Q+ SA+ Y +VH ++ N+LL G IK+SD G+
Sbjct 144 KEKEARKFFRQMISAIEYCHANLIVHRDLKPENLLLDSNGD-------IKISDFGLSNNI 196
Query 767 LSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
E + APE L L +D W G + + G P + S +E
Sbjct 197 QPGKLLESFCGSPLYAAPEILKAEKY-LGPPVDIWSLGVIMYAVLC-GNLPWEGDSQAEI 254
Query 824 -EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
+ + P + + + + P R + + + + + P
Sbjct 255 SFNSVHGNYEDPTHLSAEAVHILRRMIVPNPKDRATIQELKNHPWTNIDYQEIPKSHLPP 314
Query 883 DSPASDPTVFHKRY 896
+ +
Sbjct 315 RDAVHEIKEDIFAH 328
>sp|Q7FAZ2|LERK2_ORYSJ G-type lectin S-receptor-like serine/threonine-protein
kinase LECRK2 OS=Oryza sativa subsp. japonica
OX=39947 GN=LECRK2 PE=3 SV=1
Length=811
Score = 231 bits (588), Expect = 6e-62, Method: Composition-based stats.
Identities = 72/292 (25%), Positives = 118/292 (40%), Gaps = 14/292 (5%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
LG G G V D G +AVK ++ + + + E+ + +H +
Sbjct 523 FHEVLGTGASGIVYKGQLQ---DECGTNIAVKKIEK-LQQEAQKEFLVEVQTIGQTFHRN 578
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH-- 1015
+++ G C + EK LV E++ GSL +L S + + A + G+ YLH
Sbjct 579 LVRLLGFCNEGTEK--LLVYEFMSNGSLNTFLFNDSHPHWSLRVQVALGVSRGLFYLHEE 636
Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+ IH D+ +N+LLD++ + KI DFGLAK +P + + APE K
Sbjct 637 CNKQIIHCDMKPQNILLDDNFVAKISDFGLAKLLPVNQT--QTNTGIRGTRGYVAPEWFK 694
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGE 1132
DV+SFGV L EL+ + + + L A R+ L+ +
Sbjct 695 NIGITSKVDVYSFGVILLELVCCRKNVELEVADEEQTILTYWANDCYRCGRIDLLVASDD 754
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
K + C + E S RPT ++ +L + PS +
Sbjct 755 EAIFNIKKVERFVAVALWCLQEEPSMRPTMHKVMQMLDGAVQIPTPPDPSSY 806
Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats.
Identities = 71/406 (17%), Positives = 136/406 (33%), Gaps = 71/406 (17%)
Query 486 TVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCF 545
TV + S+ ++D + + G F S L L +L G C
Sbjct 430 TVLLKVPRSTNSPSMISSGSSKWKKDKKYWILGSSLFFGS-SVLVNFLLIFVLLFGTYCS 488
Query 546 SLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605
R SN L ++ +++ LG G VY+
Sbjct 489 ITSRKKTQLSQLPSN-----------SGLPSKIFTYRELEKATGGFHEVLGTGASGIVYK 537
Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV 665
G+L+ E + + +K ++ + F + Q
Sbjct 538 GQLQDECGTN-----------------------IAVKKIEKLQQEAQKEFLVEVQTIGQT 574
Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL 725
H +L + G C G E ++V E++ +G L+ +L H + ++ VA ++ L YL
Sbjct 575 FHRNLVRLLGFCNEGTEKLLVYEFMSNGSLNTFLF-NDSHPHWSLRVQVALGVSRGLFYL 633
Query 726 E---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIP 777
NK ++H ++ +NILL + K+SD G+ + +
Sbjct 634 HEECNKQIIHCDMKPQNILLD-------DNFVAKISDFGLAKLLPVNQTQTNTGIRGTRG 686
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP- 836
++APE +++ +D + FG LLE+ + + E+ +
Sbjct 687 YVAPEWFKNIG--ITSKVDVYSFGVILLELVCCRKNVELEVADEEQTILTYWANDCYRCG 744
Query 837 -----------------SCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ + CL EP+ RP+ +++
Sbjct 745 RIDLLVASDDEAIFNIKKVERFVAVALWCLQEEPSMRPTMHKVMQM 790
>sp|O49318|Y2317_ARATH Probable leucine-rich repeat receptor-like
protein kinase At2g33170 OS=Arabidopsis thaliana OX=3702
GN=At2g33170 PE=2 SV=1
Length=1124
Score = 234 bits (598), Expect = 6e-62, Method: Composition-based stats.
Identities = 78/316 (25%), Positives = 127/316 (40%), Gaps = 24/316 (8%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+D+ V + + + +G G G V +G+ +AV
Sbjct 792 PFFQESDIYFVPKERFTVKDILEATKGFHDSYIVGRGACGTVYKAV-----MPSGKTIAV 846
Query 930 KALKADCGPQHRSG------WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
K L+++ + + ++ EI L + H +I++ C QG S L+ EY+
Sbjct 847 KKLESNREGNNNNSNNTDNSFRAEILTLGKIRHRNIVRLYSFCYHQGSNSNLLLYEYMSR 906
Query 984 GSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLV 1037
GSL + L HS+ A EG+AYLH IHRD+ + N+L+D +
Sbjct 907 GSLGELLHGGKSHSMDWPTRFAIALGAAEGLAYLHHDCKPRIIHRDIKSNNILIDENFEA 966
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
+GDFGLAK + + + APE K D++SFGV L ELLT
Sbjct 967 HVGDFGLAKVIDMPLS--KSVSAVAGSYGYIAPEYAYTMKVTEKCDIYSFGVVLLELLTG 1024
Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLT-ELLERGERLPRPDKCPCEVY---HLMKNCWE 1153
Q P + +L + + LT E+L+ D + + C +
Sbjct 1025 KAPVQ-PLEQGGDLATWTRNHIRDHSLTSEILDPYLTKVEDDVILNHMITVTKIAVLCTK 1083
Query 1154 TEASFRPTFENLIPIL 1169
+ S RPT ++ +L
Sbjct 1084 SSPSDRPTMREVVLML 1099
Score = 172 bits (435), Expect = 4e-42, Method: Composition-based stats.
Identities = 42/247 (17%), Positives = 87/247 (35%), Gaps = 39/247 (16%)
Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655
G+G VY+ + + ++ + + E + +F
Sbjct 826 GRGACGTVYKAVMPSGKTIAVKKLESNREGNNNNSNN------------------TDNSF 867
Query 656 YETASLMSQVSHTHLAFVHGVCVRGP--ENIMVTEYVEHGPLDVWLRRERGH-VPMAWKM 712
+ ++ H ++ ++ C N+++ EY+ G L L + H + +
Sbjct 868 RAEILTLGKIRHRNIVRLYSFCYHQGSNSNLLLYEYMSRGSLGELLHGGKSHSMDWPTRF 927
Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----- 764
+A A L+YL + ++H ++ NIL+ + + D G+
Sbjct 928 AIALGAAEGLAYLHHDCKPRIIHRDIKSNNILIDE-------NFEAHVGDFGLAKVIDMP 980
Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ S ++APE ++ D + FG LLE+ G+AP+Q
Sbjct 981 LSKSVSAVAGSYGYIAPEYA--YTMKVTEKCDIYSFGVVLLELL-TGKAPVQPLEQGGDL 1037
Query 825 HFYQRQH 831
+ R H
Sbjct 1038 ATWTRNH 1044
>sp|P28028|BRAF_MOUSE Serine/threonine-protein kinase B-raf OS=Mus
musculus OX=10090 GN=Braf PE=1 SV=4
Length=751
Score = 229 bits (585), Expect = 6e-62, Method: Composition-based stats.
Identities = 74/291 (25%), Positives = 125/291 (43%), Gaps = 31/291 (11%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEI 948
+ + +G G FG V + VAVK L PQ +K E+
Sbjct 435 WEIPDGQITVGQRIGSGSFGTVYKGKWHG-------DVAVKMLNVTAPTPQQLQAFKNEV 487
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQ 1006
+LR H +I+ + G + L +V ++ SL +L + +L+ A+Q
Sbjct 488 GVLRKTRHVNILLFMGY---STKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQ 544
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+GM YLHA+ IHRDL + N+ L D VKIGDFGLA ++ E +
Sbjct 545 TAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQF-EQLSGSIL 603
Query 1067 WYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQ--SPPTKFLELIGIAQGQMTV 1121
W APE ++ + + + SDV++FG+ LYEL+T + + + ++G +
Sbjct 604 WMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDL 663
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
++ CP + LM C + + RP F ++ ++ +
Sbjct 664 SKVR------------SNCPKAMKRLMAECLKKKRDERPLFPQILASIELL 702
Score = 222 bits (566), Expect = 2e-59, Method: Composition-based stats.
Identities = 65/350 (19%), Positives = 123/350 (35%), Gaps = 56/350 (16%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
+ +IT +G G+ VY+G+ + V
Sbjct 433 DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD---------------------------V 465
Query 640 VLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+K+L+ + AF ++ + H ++ G + P+ +VT++ E L
Sbjct 466 AVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYH 524
Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
L M + +A+Q A + YL K+++H ++ NI L +K+
Sbjct 525 HLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE-------DLTVKI 577
Query 758 SDPGVGL------GALSREERVERIPWLAPECLPGG-ANSLSTAMDKWGFGATLLEICFD 810
D G+ G+ E+ I W+APE + N S D + FG L E+
Sbjct 578 GDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELM-T 636
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP------SCPQ-LATLTSQCLTYEPTQRPSFRTIL 863
G+ P + + ++ F + L +CP+ + L ++CL + +RP F IL
Sbjct 637 GQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQIL 696
Query 864 RDL----TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
+ L + + + + G +G
Sbjct 697 ASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYG 746
>sp|Q9C562|CIPKA_ARATH CBL-interacting serine/threonine-protein
kinase 10 OS=Arabidopsis thaliana OX=3702 GN=CIPK10 PE=1 SV=1
Length=479
Score = 223 bits (568), Expect = 6e-62, Method: Composition-based stats.
Identities = 53/266 (20%), Positives = 104/266 (39%), Gaps = 26/266 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960
LG+G F KV + T + VA+K + + + K+EI ++R H +++
Sbjct 18 LGQGTFAKVYYG----RSILTNQSVAIKMIDKEKVMKVGLIEQIKREISVMRIARHPNVV 73
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ + + VMEY G L + + + + + Q+ + + H++
Sbjct 74 ELYEVMATKT--RIYFVMEYCKGGELFNKVAKGKLRDDVAWKYFYQLINAVDFCHSREVY 131
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079
HRD+ N+LLD++ +K+ DFGL+ + + +P + APE + +
Sbjct 132 HRDIKPENLLLDDNENLKVSDFGLSALADCKRQDGLLHTTCGTPA-YVAPEVINRKGYDG 190
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS GV L+ LL ++ + + + + P
Sbjct 191 TKADIWSCGVVLFVLLAGYLPFHD---------------SNLMEMYRKIGKAD-FKAPSW 234
Query 1140 CPCEVYHLMKNCWETEASFRPTFENL 1165
EV L+ + R T +
Sbjct 235 FAPEVRRLLCKMLDPNPETRITIARI 260
Score = 181 bits (459), Expect = 1e-47, Method: Composition-based stats.
Identities = 55/311 (18%), Positives = 99/311 (32%), Gaps = 45/311 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
V + LGQGT VY GR + V +
Sbjct 5 PSVLTDKYDVGRLLGQGTFAKVYYGRSILTNQS------------------------VAI 40
Query 642 KVLDPSHH---DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
K++D + S+M H ++ ++ V V EY + G L
Sbjct 41 KMIDKEKVMKVGLIEQIKREISVMRIARHPNVVELYEVMATKTRIYFVMEYCKGGELFNK 100
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ + + +AWK QL +A+ + ++ + H ++ N+LL + +K+S
Sbjct 101 VAKGKLRDDVAWK--YFYQLINAVDFCHSREVYHRDIKPENLLLD-------DNENLKVS 151
Query 759 DPGVGLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
D G+ A + ++APE + T D W G L + G
Sbjct 152 DFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRKGYD-GTKADIWSCGVVL-FVLLAGY 209
Query 813 APLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P + E + + P P++ L + L P R + I +
Sbjct 210 LPFHDSNLMEMYRKIGKADFKAPSWFAPEVRRLLCKMLDPNPETRITIARIRESSWFRKG 269
Query 872 HNLADVLTVNP 882
++
Sbjct 270 LHMKQKKMEKR 280
>sp|P54646|AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic
subunit alpha-2 OS=Homo sapiens OX=9606 GN=PRKAA2 PE=1 SV=2
Length=552
Score = 225 bits (573), Expect = 6e-62, Method: Composition-based stats.
Identities = 77/274 (28%), Positives = 106/274 (39%), Gaps = 30/274 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953
+ LG G FGKV + + TG VAVK L K+EI L+
Sbjct 15 HYVLGDTLGVGTFGKVKIGEHQ----LTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012
H HIIK + +VMEYV G L DY+ +H + + QQI +
Sbjct 71 FRHPHIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE
Sbjct 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 184
Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + D+WS GV LY LL L RG
Sbjct 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLF----------------KKIRG 228
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P+ V L+ + + + R T +++
Sbjct 229 GVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDI 262
Score = 179 bits (454), Expect = 2e-46, Method: Composition-based stats.
Identities = 58/298 (19%), Positives = 96/298 (32%), Gaps = 39/298 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
Q RV LG GT V G ++ G
Sbjct 4 KQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGH----------------------- 40
Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+V +K+L+ D+ + H H+ ++ V + MV EYV G
Sbjct 41 -KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGG 99
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L ++ + G V + QQ+ SA+ Y +VH ++ N+LL
Sbjct 100 ELFDYICKH-GRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLD-------AHM 151
Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ E + APE + G + +D W G L +
Sbjct 152 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSCGVILYALLCG 210
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
P+ + +PE +ATL L +P +R + + I
Sbjct 211 TLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWF 268
>sp|Q9LMB9|CRK1_ARATH Cysteine-rich receptor-like protein kinase
1 OS=Arabidopsis thaliana OX=3702 GN=CRK1 PE=2 SV=2
Length=615
Score = 226 bits (577), Expect = 6e-62, Method: Composition-based stats.
Identities = 64/325 (20%), Positives = 128/325 (39%), Gaps = 18/325 (6%)
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919
++ ++ + + + + LG+G G V
Sbjct 281 TSLGAFISYRRVSRKRKAQVPSCVNFKYEMLEKATESFHDSMKLGQGGAGSVYKGIL--- 337
Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979
G +VAVK L + + E++++ + H+++++ GC + + LV E
Sbjct 338 --PDGRIVAVKKL-FFNTREWADQFFNEVNLISGVQHKNLVRLLGCSIEGPKS--LLVYE 392
Query 980 YVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLD 1032
YV SL L H + Q I EG+ YLH IHRD+ N+LLD
Sbjct 393 YVHNRSLDQILFMKNTVHILSWKQRFNIIIGISEGLEYLHRGSEVKIIHRDIKTSNILLD 452
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
+ KI DFGL +++ G + + + + APE L + + +DV++FGV +
Sbjct 453 RNLSPKIADFGLIRSM--GTDKTQTNTGIAGTLGYLAPEYLIKGQLTEKADVYAFGVLII 510
Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152
E++T ++ ++ L ++ + ++ +V + C
Sbjct 511 EIVTGKKNNAFT-QGTSSVLYSVWEHFKANTLDRSIDPRLKGSFVEEEALKVLQIGLLCV 569
Query 1153 ETEASFRPTFENLIPILKTVHEKYQ 1177
++ RP+ ++ +L+ K++
Sbjct 570 QSSVELRPSMSEIVFMLQNKDSKFE 594
Score = 202 bits (513), Expect = 1e-53, Method: Composition-based stats.
Identities = 72/375 (19%), Positives = 128/375 (34%), Gaps = 73/375 (19%)
Query 468 DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVR 527
G YL +ST + A+ D +R FP L
Sbjct 226 TGCYL-KYSTHKFFD---DAAEHKPDADQRNFIRSSFFPHLSDRDVTRLA---------- 271
Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587
AA+ +L + S RR + + P +N + +
Sbjct 272 --IAAISLSILTSLGAFISYRRVSRKRKAQV------------PSCVNFKYEMLEK-ATE 316
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
LGQG +VY+G L V +K L +
Sbjct 317 SFHDSMKLGQGGAGSVYKGILPDGRI-------------------------VAVKKLFFN 351
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-- 705
+ A F+ +L+S V H +L + G + GP++++V EYV + LD L +
Sbjct 352 TREWADQFFNEVNLISGVQHKNLVRLLGCSIEGPKSLLVYEYVHNRSLDQILFMKNTVHI 411
Query 706 VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ + + ++ L YL ++H ++ NILL R + K++D G+
Sbjct 412 LSWKQRFNIIIGISEGLEYLHRGSEVKIIHRDIKTSNILLDR-------NLSPKIADFGL 464
Query 763 GLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ + + + +LAPE L G L+ D + FG ++EI + +
Sbjct 465 IRSMGTDKTQTNTGIAGTLGYLAPEYLIKG--QLTEKADVYAFGVLIIEIVTGKKNNAFT 522
Query 818 RSPSEKEHFYQRQHR 832
+ S + +
Sbjct 523 QGTSSVLYSVWEHFK 537
>sp|Q2RAX3|CIPKX_ORYSJ CBL-interacting protein kinase 33 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK33 PE=2 SV=1
Length=454
Score = 222 bits (565), Expect = 6e-62, Method: Composition-based stats.
Identities = 62/270 (23%), Positives = 115/270 (43%), Gaps = 27/270 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959
+GEG F KV + TG+ VA+K L + +H+ K+EI ++ + H ++
Sbjct 18 TIGEGTFAKVKF----ARDTETGDPVAIKILDKEKVLKHKMVEQIKREISTMKLIKHPNV 73
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018
++ + ++ +V+EYV G L D + H + + + QQ+ + Y H++
Sbjct 74 VRIYEVM--GSKTNIYIVLEYVTGGELFDTIVNHGRMREDEARRYFQQLINAVDYCHSRG 131
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N+LLD+ +K+ DFGL+ + + + +P + APE L++ +
Sbjct 132 VYHRDLKPENLLLDSYGNLKVSDFGLSALSQQIKDDGLLHTTCGTPN-YVAPEVLEDQGY 190
Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
A +D+WS GV L+ LL + ++ L + + E P
Sbjct 191 DGAMADLWSCGVILFVLLAGYLPFED---------------SNLMTLYKKISNAE-FTFP 234
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L+ + R T ++
Sbjct 235 PWTSFPAKRLLTRILDPNPMTRITIPEILE 264
Score = 171 bits (434), Expect = 2e-44, Method: Composition-based stats.
Identities = 57/332 (17%), Positives = 103/332 (31%), Gaps = 44/332 (13%)
Query 579 LSFHRVDQK--EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+S +V ++ + +G+GT V RD
Sbjct 1 MSTTKVKRRVGKYELGRTIGEGTFAKV------------------------KFARDTETG 36
Query 637 LRVVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
V +K+LD H + S M + H ++ ++ V +V EYV G
Sbjct 37 DPVAIKILDKEKVLKHKMVEQIKREISTMKLIKHPNVVRIYEVMGSKTNIYIVLEYVTGG 96
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L + G + QQL +A+ Y ++ + H ++ N+LL G
Sbjct 97 ELFDTIVNH-GRMREDEARRYFQQLINAVDYCHSRGVYHRDLKPENLLLDSYG------- 148
Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+SD G+ + + ++APE L D W G L +
Sbjct 149 NLKVSDFGLSALSQQIKDDGLLHTTCGTPNYVAPEVLEDQGYD-GAMADLWSCGVILFVL 207
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
S + + + P + L ++ L P R + IL D
Sbjct 208 LAGYLPFEDSNLMTLYKKISNAEFTFPPWTSFPAKRLLTRILDPNPMTRITIPEILEDEW 267
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899
+ + + + VF+
Sbjct 268 FKKGYKRPEFDEKYDTTLDDVDAVFNDSEEHH 299
>sp|Q9FGL5|CEPR1_ARATH Receptor protein-tyrosine kinase CEPR1
OS=Arabidopsis thaliana OX=3702 GN=CEPR1 PE=1 SV=1
Length=966
Score = 233 bits (594), Expect = 6e-62, Method: Composition-based stats.
Identities = 73/282 (26%), Positives = 116/282 (41%), Gaps = 25/282 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL----KADCGPQHR----SGWKQEIDILRTL 954
+G G G V +GE+VAVK L D + + K E++ L ++
Sbjct 662 VGHGGSGTVYRVELK-----SGEVVAVKKLWSQSNKDSASEDKMHLNKELKTEVETLGSI 716
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMA 1012
H++I+K LV EY+P G+L D L + + A + +G+A
Sbjct 717 RHKNIVKLFSYFSSLDCS--LLVYEYMPNGNLWDALHKGFVHLEWRTRHQIAVGVAQGLA 774
Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH + IHRD+ + N+LLD + K+ DFG+AK + + + A
Sbjct 775 YLHHDLSPPIIHRDIKSTNILLDVNYQPKVADFGIAKVL-QARGKDSTTTVMAGTYGYLA 833
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR-LTELL 1128
PE K DV+SFGV L EL+T S + ++ ++ L E L
Sbjct 834 PEYAYSSKATIKCDVYSFGVVLMELITGKKPVDSCFGENKNIVNWVSTKIDTKEGLIETL 893
Query 1129 ERGERLPRPDKCPC-EVYHLMKNCWETEASFRPTFENLIPIL 1169
++ RL K + C + RPT ++ +L
Sbjct 894 DK--RLSESSKADMINALRVAIRCTSRTPTIRPTMNEVVQLL 933
Score = 192 bits (487), Expect = 1e-48, Method: Composition-based stats.
Identities = 70/418 (17%), Positives = 136/418 (33%), Gaps = 83/418 (20%)
Query 442 RLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAP-DGMQSL 500
R+ ++ + + P F +L + LI L+ + +
Sbjct 523 RIPENLSELL--PTSINFSSNRLSGPIPVSLIR------GGLVESFSDNPNLCIPPTAGS 574
Query 501 RLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSN 560
KFP+ Q+ + S+ + + +L G F LR+ + N
Sbjct 575 SDLKFPMCQEPHG------KKKLSSIWAIL--VSVFILVLGVIMFYLRQ------RMSKN 620
Query 561 LIIMRGARA-SPRTLNLSQLSFHRVDQKEITQLSHL------GQGTRTNVYEGRLRVEGS 613
++ + + SFHR+ + L L G G VY L+
Sbjct 621 RAVIEQDETLASSFFSYDVKSFHRISFDQREILESLVDKNIVGHGGSGTVYRVELKSGE- 679
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVL------DPSHHD---IALAFYETASLMSQ 664
V +K L D + D + +
Sbjct 680 ------------------------VVAVKKLWSQSNKDSASEDKMHLNKELKTEVETLGS 715
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
+ H ++ + +++V EY+ +G L L + H+ + +A +A L+Y
Sbjct 716 IRHKNIVKLFSYFSSLDCSLLVYEYMPNGNLWDALHKGFVHLEWRTRHQIAVGVAQGLAY 775
Query 725 LE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV-----GLGALSREERV-ER 775
L + ++H ++ NILL + K++D G+ G S +
Sbjct 776 LHHDLSPPIIHRDIKSTNILLD-------VNYQPKVADFGIAKVLQARGKDSTTTVMAGT 828
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833
+LAPE ++ + D + FG L+E+ G+ P+ S K ++
Sbjct 829 YGYLAPEYA--YSSKATIKCDVYSFGVVLMELI-TGKKPVDSCFGENKNIVNWVSTKI 883
>sp|Q92772|CDKL2_HUMAN Cyclin-dependent kinase-like 2 OS=Homo
sapiens OX=9606 GN=CDKL2 PE=1 SV=1
Length=493
Score = 223 bits (568), Expect = 7e-62, Method: Composition-based stats.
Identities = 75/283 (27%), Positives = 119/283 (42%), Gaps = 27/283 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG +G V N TG +VA+K L++D + +EI +L+ L HE+++
Sbjct 10 VGEGSYGMVM----KCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
C + +K LV E+V L D L + + + + QI G+ + H+ + I
Sbjct 66 LLEVC--KKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNII 123
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFY 1079
HRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L K+
Sbjct 124 HRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVKYG 180
Query 1080 YASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
A DVW+ G + E+ DS + +G + L + G RL
Sbjct 181 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL 240
Query 1135 P----------RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P R K V L K C + RP L+
Sbjct 241 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLH 283
Score = 161 bits (408), Expect = 7e-41, Method: Composition-based stats.
Identities = 56/320 (18%), Positives = 101/320 (32%), Gaps = 70/320 (22%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-L 644
++ L +G+G+ V + R + G V +K L
Sbjct 1 MEKYENLGLVGEGSYGMVMKCRNKDTGR------------------------IVAIKKFL 36
Query 645 DPSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ + L+ Q+ H +L + VC + +V E+V+H LD L
Sbjct 37 ESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDD-LELFP 95
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ Q+ + + + + N++H ++ NIL+++ G+ +KL D G
Sbjct 96 NGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFA 148
Query 764 LGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ + V + APE L G A+D W G + E+
Sbjct 149 RTLAAPGEVYTDYVATRWYRAPELLV-GDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSD 207
Query 820 PSEKEHFYQ-------------------RQHRLPEPS------------CPQLATLTSQC 848
+ H RLPE + L +C
Sbjct 208 IDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKC 267
Query 849 LTYEPTQRPSFRTILRDLTR 868
L +P +RP +L
Sbjct 268 LHIDPDKRPFCAELLHHDFF 287
>sp|Q755C4|IPL1_EREGS Spindle assembly checkpoint kinase OS=Eremothecium
gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923
/ NRRL Y-1056) OX=284811 GN=IPL1 PE=3 SV=1
Length=367
Score = 219 bits (558), Expect = 7e-62, Method: Composition-based stats.
Identities = 74/360 (21%), Positives = 139/360 (39%), Gaps = 41/360 (11%)
Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+G P P + +R P + + P +RP+
Sbjct 33 TNGAPPQARVQP-------GKGYRNPGKVLSPI-----RNQEMSPGKRPTLEISELKNVS 80
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
P S + + LG+G FG+V + +G + A
Sbjct 81 PINQAHKTGKARAGGVPLSKLQNLKLADFEIGKVLGKGKFGRVYCV----RHIESGFVCA 136
Query 929 VKALKADCGPQH--RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
+KA++ Q+ +++E++I +L H ++ + G D EK + L+MEY+ G L
Sbjct 137 LKAMEKKDIIQYNIEKQFRREVEIQSSLRHPNLTQLYGYFHD--EKRVYLLMEYLVNGEL 194
Query 987 RDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045
+L R + Q+ + + Y+H ++ +HRD+ N+++ + +K+ DFG +
Sbjct 195 YKHLKGRSHFNDVVASYYVYQMADALDYMHERNILHRDIKPENIIIGFNNTIKLTDFGWS 254
Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105
P+G + R+ V + +PE ++ ++ DVW+ GV YELL +
Sbjct 255 VITPKGSK----RKTLCGTVDYLSPELIRSREYNEKVDVWALGVLTYELLVGSPPFEEES 310
Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ L +L+R L PD E HL+ E + R + +
Sbjct 311 KE--------------LTYKRILKRN--LIFPDHVDTEARHLISRLLEYDPGDRIPLKEV 354
Score = 184 bits (468), Expect = 7e-50, Method: Composition-based stats.
Identities = 65/348 (19%), Positives = 118/348 (34%), Gaps = 46/348 (13%)
Query 534 QGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASP----------RTLNLSQLSFHR 583
G R S R PG+ L I SP R +
Sbjct 44 PGKGYRNPGKVLSPIRNQEMSPGKRPTLEISELKNVSPINQAHKTGKARAGGVPLSKLQN 103
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ + LG+G VY R G + ++
Sbjct 104 LKLADFEIGKVLGKGKFGRVYCVRHIESGFVCALK---------------------AMEK 142
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
D ++I F + S + H +L ++G ++ EY+ +G L L+ R
Sbjct 143 KDIIQYNIEKQFRREVEIQSSLRHPNLTQLYGYFHDEKRVYLLMEYLVNGELYKHLKG-R 201
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
H Q+A AL Y+ +N++H ++ NI++ G + IKL+D G
Sbjct 202 SHFNDVVASYYVYQMADALDYMHERNILHRDIKPENIII-------GFNNTIKLTDFGWS 254
Query 764 L---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+ R+ + +L+PE + + + +D W G E+ G P + S
Sbjct 255 VITPKGSKRKTLCGTVDYLSPELIR--SREYNEKVDVWALGVLTYELLV-GSPPFEEESK 311
Query 821 SEKEHFYQRQHRL-PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+++ + P+ + L S+ L Y+P R + + +
Sbjct 312 ELTYKRILKRNLIFPDHVDTEARHLISRLLEYDPGDRIPLKEVKKHPW 359
>sp|Q9LSV3|WAKLS_ARATH Putative wall-associated receptor kinase-like
16 OS=Arabidopsis thaliana OX=3702 GN=WAKL16 PE=3 SV=1
Length=433
Score = 221 bits (563), Expect = 7e-62, Method: Composition-based stats.
Identities = 68/258 (26%), Positives = 109/258 (42%), Gaps = 13/258 (5%)
Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
+VA+K + Q + E+ +L + H +++K GCC + E L LV E++ GS
Sbjct 132 IVAIKKTRLGDNNQ-VEQFINEVLVLSQINHRNVVKLLGCCLE-TEVPL-LVYEFITGGS 188
Query 986 LRDYLPRH----SIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVK 1038
L D+L S+ L A ++ +AYLH+ IHRD+ N+LLD + K
Sbjct 189 LFDHLHGSMFVSSLTWEHRLEIAIEVAGAIAYLHSGASIPIIHRDIKTENILLDENLTAK 248
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
+ DFG +K P E G + + PE + SDV+SFGV L EL++
Sbjct 249 VADFGASKLKPMDKEQLTTMVQG--TLGYLDPEYYTTWLLNEKSDVYSFGVVLMELISGQ 306
Query 1099 DSS-QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157
+ P L+ RL E+++ + E + C +
Sbjct 307 KALCFERPETSKHLVSYFVLATKENRLHEIIDDQVLNEENQREIHEAARVAVECTRLKGE 366
Query 1158 FRPTFENLIPILKTVHEK 1175
RP + L+T+ K
Sbjct 367 ERPRMIEVAAELETLRAK 384
Score = 201 bits (510), Expect = 8e-55, Method: Composition-based stats.
Identities = 61/362 (17%), Positives = 122/362 (34%), Gaps = 63/362 (17%)
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGS 613
++I R + A ++ + + LGQG + VY+G L
Sbjct 73 KNGGGMLIERLSGAGSSNIDFKIFTEEDMKEATNGYDVSRILGQGGQWTVYKGILPDNSI 132
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
V +K ++ F ++SQ++H ++ +
Sbjct 133 -------------------------VAIKKTRLGDNNQVEQFINEVLVLSQINHRNVVKL 167
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK--- 728
G C+ ++V E++ G L L + W ++ +A ++A A++YL +
Sbjct 168 LGCCLETEVPLLVYEFITGGSLFDHLHGSMFVSSLTWEHRLEIAIEVAGAIAYLHSGASI 227
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPEC 783
++H ++ NILL + K++D G +E++ + +L PE
Sbjct 228 PIIHRDIKTENILLDE-------NLTAKVADFGASKLKPMDKEQLTTMVQGTLGYLDPEY 280
Query 784 LPGGANSLSTAMDKWGFGATLLEICFDG-----EAPLQSRSPSEKEHFYQRQHRLPEPSC 838
L+ D + FG L+E+ E P S+ +++RL E
Sbjct 281 YTTWL--LNEKSDVYSFGVVLMELISGQKALCFERPETSKHLVSYFVLATKENRLHEIID 338
Query 839 PQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
Q+ A + +C + +RP + +L L+
Sbjct 339 DQVLNEENQREIHEAARVAVECTRLKGEERPRMIEVAAELETLRAKTTKHNWLDQYPEEN 398
Query 887 SD 888
Sbjct 399 VH 400
>sp|Q94C95|ATG1A_ARATH Serine/threonine-protein kinase ATG1a OS=Arabidopsis
thaliana OX=3702 GN=ATG1A PE=1 SV=1
Length=626
Score = 227 bits (578), Expect = 7e-62, Method: Composition-based stats.
Identities = 80/296 (27%), Positives = 123/296 (42%), Gaps = 33/296 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+G G F V L + +G VAVK + K P+ R +EI IL T+ H +I
Sbjct 14 PRIGSGSFAVVWL----AKHRSSGLEVAVKEIDKKLLSPKVRDNLLKEISILSTIDHPNI 69
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018
I++ E + LV+EY G L Y+ RH + A F +Q+ G+ L +H
Sbjct 70 IRFYEAIETGD--RIFLVLEYCSGGDLAGYINRHGKVPEAVAKHFMRQLALGLQVLQEKH 127
Query 1019 YIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+IHRDL +N+LL + + +KIGDFG A+++ + E + APE ++
Sbjct 128 FIHRDLKPQNLLLSSKEVTPLLKIGDFGFARSLTPE----SMAETFCGSPLYMAPEIIRN 183
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
K+ +D+WS G L++L+T PP I + + L R
Sbjct 184 QKYDAKADLWSAGAILFQLVTGK-----PPFDGNNHIQLFHNIVRDTELK--FPEDTRNE 236
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV----FSVC 1187
C L++ R TF + + Q P V FS C
Sbjct 237 IHPDCVDLCRSLLRR----NPIERLTFRE---FFNHMFLREPRQIPDVEHSGFSTC 285
Score = 190 bits (483), Expect = 1e-49, Method: Composition-based stats.
Identities = 62/309 (20%), Positives = 107/309 (35%), Gaps = 43/309 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ +G G+ V+ + R G L V +K +D
Sbjct 9 DYALGPRIGSGSFAVVWLAKHRSSG------------------------LEVAVKEIDKK 44
Query 648 --HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ + S++S + H ++ + G +V EY G L ++ R G
Sbjct 45 LLSPKVRDNLLKEISILSTIDHPNIIRFYEAIETGDRIFLVLEYCSGGDLAGYINRH-GK 103
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
VP A +QLA L L+ K+ +H ++ +N+LL+ + +P +K+ D G
Sbjct 104 VPEAVAKHFMRQLALGLQVLQEKHFIHRDLKPQNLLLSS----KEVTPLLKIGDFGFARS 159
Query 766 ALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
E ++APE + D W GA L ++ G+ P + +
Sbjct 160 LTPESMAETFCGSPLYMAPEIIRN--QKYDAKADLWSAGAILFQLV-TGKPPFDGNNHIQ 216
Query 823 KEHFYQRQHRLPEPSC------PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
H R L P P L L P +R +FR + +P + D
Sbjct 217 LFHNIVRDTELKFPEDTRNEIHPDCVDLCRSLLRRNPIERLTFREFFNHMFLREPRQIPD 276
Query 877 VLTVNPDSP 885
V +
Sbjct 277 VEHSGFSTC 285
>sp|Q09137|AAPK2_RAT 5'-AMP-activated protein kinase catalytic
subunit alpha-2 OS=Rattus norvegicus OX=10116 GN=Prkaa2 PE=1
SV=1
Length=552
Score = 225 bits (573), Expect = 7e-62, Method: Composition-based stats.
Identities = 76/274 (28%), Positives = 106/274 (39%), Gaps = 30/274 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953
+ LG G FGKV + + TG VAVK L K+EI L+
Sbjct 15 HYVLGDTLGVGTFGKVKIGEHQ----LTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012
H HIIK + +VMEYV G L DY+ +H + + QQI +
Sbjct 71 FRHPHIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVD 128
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE
Sbjct 129 YCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 184
Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + D+WS GV LY LL L RG
Sbjct 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLF----------------KKIRG 228
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P+ + L+ + + + R T +++
Sbjct 229 GVFYIPEYLNRSIATLLMHMLQVDPLKRATIKDI 262
Score = 179 bits (453), Expect = 3e-46, Method: Composition-based stats.
Identities = 58/298 (19%), Positives = 96/298 (32%), Gaps = 39/298 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
Q RV LG GT V G ++ G
Sbjct 4 KQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGH----------------------- 40
Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+V +K+L+ D+ + H H+ ++ V + MV EYV G
Sbjct 41 -KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGG 99
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L ++ + G V + QQ+ SA+ Y +VH ++ N+LL
Sbjct 100 ELFDYICKH-GRVEEVEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLD-------AQM 151
Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ E + APE + G + +D W G L +
Sbjct 152 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSCGVILYALLCG 210
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
P+ + +PE +ATL L +P +R + + I
Sbjct 211 TLPFDDEHVPTLFKKIRGGVFYIPEYLNRSIATLLMHMLQVDPLKRATIKDIREHEWF 268
>sp|Q9M345|LRK42_ARATH L-type lectin-domain containing receptor
kinase IV.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK42 PE=2
SV=1
Length=677
Score = 228 bits (581), Expect = 7e-62, Method: Composition-based stats.
Identities = 74/277 (27%), Positives = 116/277 (42%), Gaps = 18/277 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG+V Y T VAVK + D Q + EI + + H +++
Sbjct 353 LGSGGFGRV----YRGILPTTKLEVAVKRVSHD-SKQGMKEFVAEIVSIGRMSHRNLVPL 407
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018
G C +GE L LV +Y+P GSL YL P ++ Q + + G+ YLH +
Sbjct 408 LGYCRRRGE--LLLVYDYMPNGSLDKYLYNNPETTLDWKQRSTIIKGVASGLFYLHEEWE 465
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ A NVLLD D ++GDFGLA+ G + + + APE +
Sbjct 466 QVVIHRDVKASNVLLDADFNGRLGDFGLARLYDHGSDPQTTH--VVGTLGYLAPEHSRTG 523
Query 1077 KFYYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ +DV++FG L E+++ S L+ + E +
Sbjct 524 RATTTTDVYAFGAFLLEVVSGRRPIEFHSASDDTFLLVEWVFSLWLRGNIMEAKDPKLGS 583
Query 1135 PRPDKCPCEV-YHLMKNCWETEASFRPTFENLIPILK 1170
D E+ L C ++ RP+ ++ L+
Sbjct 584 SGYDLEEVEMVLKLGLLCSHSDPRARPSMRQVLQYLR 620
Score = 209 bits (531), Expect = 2e-55, Method: Composition-based stats.
Identities = 67/310 (22%), Positives = 110/310 (35%), Gaps = 63/310 (20%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
K + LG G VY G L +L V +K +
Sbjct 343 ATKGFKEKDLLGSGGFGRVYRGIL------------------------PTTKLEVAVKRV 378
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-R 703
F + ++SH +L + G C R E ++V +Y+ +G LD +L
Sbjct 379 SHDSKQGMKEFVAEIVSIGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNNPE 438
Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ + + + +AS L YL + ++H +V N+LL +L D
Sbjct 439 TTLDWKQRSTIIKGVASGLFYLHEEWEQVVIHRDVKASNVLLD-------ADFNGRLGDF 491
Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ V + +LAPE G + +T D + FGA LLE+ G P+
Sbjct 492 GLARLYDHGSDPQTTHVVGTLGYLAPEHSRTGRATTTT--DVYAFGAFLLEVVS-GRRPI 548
Query 816 QSRSPSEKEHF-------YQRQHRLPEPSCPQLAT-------------LTSQCLTYEPTQ 855
+ S S+ + + E P+L + L C +P
Sbjct 549 EFHSASDDTFLLVEWVFSLWLRGNIMEAKDPKLGSSGYDLEEVEMVLKLGLLCSHSDPRA 608
Query 856 RPSFRTILRD 865
RPS R +L+
Sbjct 609 RPSMRQVLQY 618
>sp|Q9S7U9|M2K2_ARATH Mitogen-activated protein kinase kinase
2 OS=Arabidopsis thaliana OX=3702 GN=MKK2 PE=1 SV=2
Length=363
Score = 219 bits (557), Expect = 7e-62, Method: Composition-based stats.
Identities = 63/268 (24%), Positives = 116/268 (43%), Gaps = 20/268 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G G V L + TG+ A+K ++ + R QE+ I ++ +++
Sbjct 76 IGKGSSGVVQLVQHK----WTGQFFALKVIQLNIDEAIRKAIAQELKINQSSQCPNLVTS 131
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHA-QHYI 1020
D G ++ L++EY+ GSL D+L +I + L +Q+ +G+ YLH +H I
Sbjct 132 YQSFYDNG--AISLILEYMDGGSLADFLKSVKAIPDSYLSAIFRQVLQGLIYLHHDRHII 189
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDL N+L+++ VKI DFG++ + + + +PE + K+
Sbjct 190 HRDLKPSNLLINHRGEVKITDFGVSTVM---TNTAGLANTFVGTYNYMSPERIVGNKYGN 246
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD-K 1139
SD+WS G+ + E T P + +V L E + P
Sbjct 247 KSDIWSLGLVVLECATGKFPYAPP--------NQEETWTSVFELMEAIVDQPPPALPSGN 298
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
E+ + C + + + R + + L+
Sbjct 299 FSPELSSFISTCLQKDPNSRSSAKELME 326
Score = 167 bits (424), Expect = 4e-44, Method: Composition-based stats.
Identities = 56/317 (18%), Positives = 118/317 (37%), Gaps = 51/317 (16%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
++ P L+ + + ++ ++ + +G+G+ V
Sbjct 48 SQLEPEVLSPIKPADDQLSLSDLDMVKVIGKGSSGVV----------------------Q 85
Query 627 LVPGRDRGQELRVVLKVLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
LV + GQ LKV+ + + I A + + +L + +
Sbjct 86 LVQHKWTGQFF--ALKVIQLNIDEAIRKAIAQELKINQSSQCPNLVTSYQSFYDNGAISL 143
Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE-NKNLVHGNVCGRNILLAR 744
+ EY++ G L +L+ + +P ++ + +Q+ L YL +++++H ++ N+L+
Sbjct 144 ILEYMDGGSLADFLKSVKA-IPDSYLSAIFRQVLQGLIYLHHDRHIIHRDLKPSNLLINH 202
Query 745 LGLAEGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGF 800
G +K++D GV + V +++PE + G N D W
Sbjct 203 RGE-------VKITDFGVSTVMTNTAGLANTFVGTYNYMSPERIVG--NKYGNKSDIWSL 253
Query 801 GATLLEICFDGEAPLQSRSPSE----KEHFYQRQHRLPE------PSCPQLATLTSQCLT 850
G +LE C G+ P + E + P P+L++ S CL
Sbjct 254 GLVVLE-CATGKFPYAPPNQEETWTSVFELMEAIVDQPPPALPSGNFSPELSSFISTCLQ 312
Query 851 YEPTQRPSFRTILRDLT 867
+P R S + ++
Sbjct 313 KDPNSRSSAKELMEHPF 329
>sp|Q9SJT0|Y2214_ARATH Probable receptor-like protein kinase At2g21480
OS=Arabidopsis thaliana OX=3702 GN=At2g21480 PE=3 SV=1
Length=871
Score = 231 bits (590), Expect = 7e-62, Method: Composition-based stats.
Identities = 73/275 (27%), Positives = 114/275 (41%), Gaps = 17/275 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + D G VA+K Q + + EI +L L H H++
Sbjct 531 IGVGGFGNVYIGTID-----DGTQVAIKRGNP-QSEQGITEFHTEIQMLSKLRHRHLVSL 584
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAYLHA--- 1016
G C++ E + LV EY+ G RD+L ++ Q L G+ YLH
Sbjct 585 IGYCDENAE--MILVYEYMSNGPFRDHLYGKNLSPLTWKQRLEICIGAARGLHYLHTGTA 642
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
Q IHRD+ + N+LLD + K+ DFGL+K V G + V + PE +
Sbjct 643 QGIIHRDVKSTNILLDEALVAKVADFGLSKDVAFGQNH--VSTAVKGSFGYLDPEYFRRQ 700
Query 1077 KFYYASDVWSFGVTLYE-LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ SDV+SFGV L E L + P + + L A L ++++
Sbjct 701 QLTDKSDVYSFGVVLLEALCARPAINPQLPREQVNLAEWAMLWKQKGLLEKIIDPHLVGA 760
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ + + C RPT +++ L+
Sbjct 761 VNPESMKKFAEAAEKCLADYGVDRPTMGDVLWNLE 795
Score = 216 bits (551), Expect = 7e-57, Method: Composition-based stats.
Identities = 62/309 (20%), Positives = 106/309 (34%), Gaps = 60/309 (19%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
K +G G NVY G + +V +K +
Sbjct 522 TKNFDASEIIGVGGFGNVYIGTIDDG-------------------------TQVAIKRGN 556
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-G 704
P F+ ++S++ H HL + G C E I+V EY+ +GP L +
Sbjct 557 PQSEQGITEFHTEIQMLSKLRHRHLVSLIGYCDENAEMILVYEYMSNGPFRDHLYGKNLS 616
Query 705 HVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
+ ++ + A L YL + ++H +V NILL +A K++D G
Sbjct 617 PLTWKQRLEICIGAARGLHYLHTGTAQGIIHRDVKSTNILLDEALVA-------KVADFG 669
Query 762 VGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG----- 811
+ + V +L PE L+ D + FG LLE
Sbjct 670 LSKDVAFGQNHVSTAVKGSFGYLDPEYFR--RQQLTDKSDVYSFGVVLLEALCARPAINP 727
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQL------------ATLTSQCLTYEPTQRPSF 859
+ P + + +E ++++ L + P L A +CL RP+
Sbjct 728 QLPREQVNLAEWAMLWKQKGLLEKIIDPHLVGAVNPESMKKFAEAAEKCLADYGVDRPTM 787
Query 860 RTILRDLTR 868
+L +L
Sbjct 788 GDVLWNLEY 796
>sp|Q9FP13|SERL2_ORYSJ LRR receptor kinase SERL2 OS=Oryza sativa
subsp. japonica OX=39947 GN=SERL2 PE=1 SV=1
Length=640
Score = 227 bits (578), Expect = 7e-62, Method: Composition-based stats.
Identities = 71/320 (22%), Positives = 128/320 (40%), Gaps = 15/320 (5%)
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916
R + L + + +V N + LG+G FG V
Sbjct 264 WRHRRNRQILFDVDEQQIENVNLGNVKRFSFRELQAATEGFSGKNILGKGGFGNVYRGQL 323
Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976
G +VAVK LK + ++ E++++ H ++++ G C E+ L
Sbjct 324 -----PDGTLVAVKRLKDGNAAGGEAQFQTEVEMISLALHRNLLRLYGFCMTATER--LL 376
Query 977 VMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLD 1032
V ++ GS+ L + ++ A G+ YLH Q IHRD+ A NVLLD
Sbjct 377 VYPFMSNGSVASRLKAKPALEWGTRRRIAVGAARGLVYLHEQCDPKIIHRDVKAANVLLD 436
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
+GDFGLAK + + V V APE L + +DV+ FG+ L
Sbjct 437 EACEAVVGDFGLAKLLDHRESH--VTTAVRGTVGHIAPEYLSTGQSSDRTDVFGFGILLL 494
Query 1093 ELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
EL+T + + + + ++ + + ++ L+++G E+ +
Sbjct 495 ELVTGQTALEFGKSSNHKGAMLDWVKKMQSEKKVEVLVDKGLGGGYDRVEVEEMVQVALL 554
Query 1151 CWETEASFRPTFENLIPILK 1170
C + + RP +++ +L+
Sbjct 555 CTQYLPAHRPRMSDVVRMLE 574
Score = 185 bits (470), Expect = 8e-48, Method: Composition-based stats.
Identities = 63/320 (20%), Positives = 111/320 (35%), Gaps = 64/320 (20%)
Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
N+ + SF + + + + LG+G NVY G+L
Sbjct 288 NVKRFSFRELQAATEGFSGKNILGKGGFGNVYRGQLPDG--------------------- 326
Query 633 RGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
V +K L D + F ++S H +L ++G C+ E ++V ++
Sbjct 327 ----TLVAVKRLKDGNAAGGEAQFQTEVEMISLALHRNLLRLYGFCMTATERLLVYPFMS 382
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748
+G + L+ + + + +A A L YL + ++H +V N+LL A
Sbjct 383 NGSVASRLKA-KPALEWGTRRRIAVGAARGLVYLHEQCDPKIIHRDVKAANVLLDEACEA 441
Query 749 EGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+ D G+ RE V + +APE L G + S D +GFG
Sbjct 442 V-------VGDFGLAKLLDHRESHVTTAVRGTVGHIAPEYLSTGQS--SDRTDVFGFGIL 492
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLP------------------EPSCPQLATLT 845
LLE+ A +S + K ++ ++ +
Sbjct 493 LLELVTGQTALEFGKSSNHKGAMLDWVKKMQSEKKVEVLVDKGLGGGYDRVEVEEMVQVA 552
Query 846 SQCLTYEPTQRPSFRTILRD 865
C Y P RP ++R
Sbjct 553 LLCTQYLPAHRPRMSDVVRM 572
>sp|O54748|STK3_RAT Serine/threonine-protein kinase 3 OS=Rattus
norvegicus OX=10116 GN=Stk3 PE=1 SV=1
Length=491
Score = 223 bits (568), Expect = 7e-62, Method: Composition-based stats.
Identities = 63/268 (24%), Positives = 109/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V + + +G++VA+K + + +EI I++ +++K
Sbjct 32 KLGEGSYGSV----FKAIHKESGQVVAIKQVPVES---DVQEIIKEISIMQQCDSPYVVK 84
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ + +G+ YLH
Sbjct 85 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRK 142
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 143 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 199
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 200 CVADIWSLGITSIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 246
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ +K C R T L+
Sbjct 247 WSDDFTDFVKKCLVKSPEQRATATQLLQ 274
Score = 198 bits (504), Expect = 2e-53, Method: Composition-based stats.
Identities = 56/307 (18%), Positives = 98/307 (32%), Gaps = 44/307 (14%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
+ LS+ S + ++ L LG+G+ +V++ + G
Sbjct 7 PKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQ--------------- 51
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
V +K + + S+M Q ++ +G + + +V E
Sbjct 52 ---------VVAIKQVPVESD--VQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVME 100
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
Y G + +R + + + L YL +H ++ NILL G
Sbjct 101 YCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-- 158
Query 749 EGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
KL+D GV R + W+APE + + D W G T
Sbjct 159 -----HAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITS 211
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
+E+ +G+ P P R PE +CL P QR +
Sbjct 212 IEMA-EGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATAT 270
Query 861 TILRDLT 867
+L+
Sbjct 271 QLLQHPF 277
>sp|Q6CWQ4|IPL1_KLULA Spindle assembly checkpoint kinase OS=Kluyveromyces
lactis (strain ATCC 8585 / CBS 2359 / DSM 70799
/ NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=IPL1 PE=3 SV=1
Length=361
Score = 219 bits (557), Expect = 7e-62, Method: Composition-based stats.
Identities = 68/315 (22%), Positives = 129/315 (41%), Gaps = 29/315 (9%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
+ P R L +P+ + + + + LG+G FGKV
Sbjct 57 STGPVNNNPRRSLMVKKPNTAHGTRVPILNDHNDKFENMTLQDFEIGKILGKGKFGKVYC 116
Query 914 YCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
+ TG + A+KA++ Q+ + +++E++I + H+++ + G D E
Sbjct 117 V----KHRETGLICALKAMEKKEIVQYTIQKQFRREVEIQGSFKHKNLTQLYGFFYD--E 170
Query 972 KSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030
K + L+MEYV G L +L + + F Q+ + Y+H+++ +HRD+ N+L
Sbjct 171 KRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDYMHSKNILHRDIKPENIL 230
Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
+ + +K+ DFG + +G + R+ + + +PE +K ++ DVW+ GV
Sbjct 231 IGFNNTIKLTDFGWSVYNEDGQK----RKTLCGTIDYLSPELIKSREYNNKVDVWALGVL 286
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
YELL + + MT R+ L P + L+
Sbjct 287 TYELLVGSPPFEEDTKE-----------MTYRRILRCD-----LKFPLNVSPQARDLIVR 330
Query 1151 CWETEASFRPTFENL 1165
+ E S R +
Sbjct 331 LLQFEPSKRIPLSEV 345
Score = 186 bits (473), Expect = 1e-50, Method: Composition-based stats.
Identities = 60/298 (20%), Positives = 104/298 (35%), Gaps = 36/298 (12%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
LN F + ++ LG+G VY + R G + E
Sbjct 85 LNDHNDKFENMTLQDFEIGKILGKGKFGKVYCVKHRETGLICALKAMEKKEIVQYT---- 140
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
I F + H +L ++G ++ EYV +G
Sbjct 141 -----------------IQKQFRREVEIQGSFKHKNLTQLYGFFYDEKRVYLLMEYVYYG 183
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L +L+ G + Q+A+AL Y+ +KN++H ++ NIL+ G +
Sbjct 184 ELYKFLKNN-GPLNETLASYFVYQMANALDYMHSKNILHRDIKPENILI-------GFNN 235
Query 754 FIKLSDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
IKL+D G + R+ I +L+PE + + + +D W G E+
Sbjct 236 TIKLTDFGWSVYNEDGQKRKTLCGTIDYLSPELIK--SREYNNKVDVWALGVLTYELLV- 292
Query 811 GEAPLQSRSPSEKEHFYQR-QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
G P + + R + P PQ L + L +EP++R +
Sbjct 293 GSPPFEEDTKEMTYRRILRCDLKFPLNVSPQARDLIVRLLQFEPSKRIPLSEVKSHAW 350
>sp|A1CPG7|HOG1_ASPCL Mitogen-activated protein kinase hog1 OS=Aspergillus
clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816
/ NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=hog1 PE=3
SV=1
Length=365
Score = 219 bits (557), Expect = 7e-62, Method: Composition-based stats.
Identities = 67/283 (24%), Positives = 109/283 (39%), Gaps = 29/283 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + TG+ VAVK + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SARDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L + ER P + + L++ + R +
Sbjct 252 SLPKRERQPLANKFKNADPDAVDLLERMLVFDPKKRIRATEAL 294
Score = 134 bits (336), Expect = 2e-32, Method: Composition-based stats.
Identities = 36/231 (16%), Positives = 74/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + RD+ V +K ++ P ++ Y
Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSARDQLTGQPVAVKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSTGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q2V452|CIPK3_ARATH CBL-interacting serine/threonine-protein
kinase 3 OS=Arabidopsis thaliana OX=3702 GN=CIPK3 PE=1 SV=2
Length=441
Score = 221 bits (564), Expect = 7e-62, Method: Composition-based stats.
Identities = 68/288 (24%), Positives = 120/288 (42%), Gaps = 31/288 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959
+GEG F KV N TGE VA+K L + +H+ ++EI ++ + H ++
Sbjct 19 TIGEGTFAKVKF----ARNSETGEPVALKILDKEKVLKHKMAEQIRREIATMKLIKHPNV 74
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
++ + + + +++EYV G L D + + + + QQ+ + Y H++
Sbjct 75 VQLYEVMASKTK--IFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLIHAVDYCHSRG 132
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N+LLD+ +KI DFGL+ + + + +P + APE L + +
Sbjct 133 VYHRDLKPENLLLDSYGNLKISDFGLSALSQQVRDDGLLHTSCGTPN-YVAPEVLNDRGY 191
Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
A +D+WS GV LY LL ++ L + + GE P
Sbjct 192 DGATADMWSCGVVLYVLLAGYLPFDD---------------SNLMNLYKKISSGE-FNCP 235
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
L+ + R T + + + + Y+ P VF
Sbjct 236 PWLSLGAMKLITRILDPNPMTRVTPQEVFED-EWFKKDYK---PPVFE 279
Score = 172 bits (436), Expect = 7e-45, Method: Composition-based stats.
Identities = 58/335 (17%), Positives = 101/335 (30%), Gaps = 46/335 (14%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
+N Q RV + E+ +G+GT V R+
Sbjct 1 MNRRQQVKRRVGKYEV--GRTIGEGTFAKV------------------------KFARNS 34
Query 634 GQELRVVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
V LK+LD H +A + M + H ++ ++ V + ++ EYV
Sbjct 35 ETGEPVALKILDKEKVLKHKMAEQIRREIATMKLIKHPNVVQLYEVMASKTKIFIILEYV 94
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L + G + QQL A+ Y ++ + H ++ N+LL G
Sbjct 95 TGGELFDKI-VNDGRMKEDEARRYFQQLIHAVDYCHSRGVYHRDLKPENLLLDSYG---- 149
Query 751 TSPFIKLSDPGVG------LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+K+SD G+ ++APE L D W G L
Sbjct 150 ---NLKISDFGLSALSQQVRDDGLLHTSCGTPNYVAPEVLNDRGYD-GATADMWSCGVVL 205
Query 805 LEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
+ G P + + P L ++ L P R + + +
Sbjct 206 Y-VLLAGYLPFDDSNLMNLYKKISSGEFNCPPWLSLGAMKLITRILDPNPMTRVTPQEVF 264
Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898
D + + + + VF
Sbjct 265 EDEWFKKDYKPPVFEERDDSNMDDIDAVFKDSEEH 299
>sp|A8XJW8|CST1_CAEBR Serine/threonine-protein kinase cst-1 OS=Caenorhabditis
briggsae OX=6238 GN=cst-1 PE=3 SV=2
Length=494
Score = 223 bits (568), Expect = 7e-62, Method: Composition-based stats.
Identities = 62/262 (24%), Positives = 113/262 (43%), Gaps = 31/262 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V + + +G ++A+K + D Q +EI I++ ++++K
Sbjct 40 KLGEGSYGSV----HKAIHKESGHVLAIKKVPVDTDLQ---EIIKEISIMQQCKSKYVVK 92
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D + R + ++ + +G+ YLH
Sbjct 93 YYGSYFKNSD--LWIVMEYCGAGSISDIMRARRKPLSEKEISAVLRDTLKGLQYLHDLKK 150
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ D + K+ DFG+A + + R FW APE ++E +
Sbjct 151 IHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIEEIGYD 207
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL--ERGERLPRP 1137
+D+WS G+T E+ + +R ++ + +P
Sbjct 208 TKADIWSLGITAIEMAEGRPP---------------YSDIHPMRAIFMIPTKPPPTFKKP 252
Query 1138 DKCPCEVYHLMKNCWETEASFR 1159
++ E ++ C + R
Sbjct 253 EEWSSEFNDFIRCCLIKKPEER 274
Score = 192 bits (489), Expect = 2e-51, Method: Composition-based stats.
Identities = 55/302 (18%), Positives = 101/302 (33%), Gaps = 44/302 (15%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L + ++ ++ + LG+G+ +V++ + G
Sbjct 20 FKLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHKESGHVL------------------ 61
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+K + P D+ + S+M Q ++ +G + + +V EY G
Sbjct 62 ------AIKKV-PVDTDLQ-EIIKEISIMQQCKSKYVVKYYGSYFKNSDLWIVMEYCGAG 113
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
+ +R R + V + L YL + +H ++ NILL G+A
Sbjct 114 SISDIMRARRKPLSEKEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIA----- 168
Query 754 FIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
KL+D GV R + W+APE + T D W G T +E+
Sbjct 169 --KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIG--YDTKADIWSLGITAIEMA- 223
Query 810 DGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+G P P + + PE + CL +P +R + +
Sbjct 224 EGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRCCLIKKPEERKTALRLCEH 283
Query 866 LT 867
Sbjct 284 TF 285
>sp|A2XQD3|LERK2_ORYSI G-type lectin S-receptor-like serine/threonine-protein
kinase LECRK2 OS=Oryza sativa subsp. indica
OX=39946 GN=LECRK2 PE=2 SV=1
Length=811
Score = 230 bits (587), Expect = 7e-62, Method: Composition-based stats.
Identities = 71/292 (24%), Positives = 118/292 (40%), Gaps = 14/292 (5%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
LG G G V D G +AVK ++ + + + E+ + +H +
Sbjct 523 FHEVLGTGASGIVYKGQLQ---DECGTNIAVKKIEK-LQQEAQKEFLVEVQTIGQTFHRN 578
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH-- 1015
+++ G C + EK LV E++ GSL +L + + + A + G+ YLH
Sbjct 579 LVRLLGFCNEGTEK--LLVYEFMSNGSLNTFLFNDTHPHWSLRVQVALGVSRGLLYLHEE 636
Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
+ IH D+ +N+LLD++ + KI DFGLAK +P + + APE K
Sbjct 637 CNKQIIHCDMKPQNILLDDNFVAKISDFGLAKLLPVNQT--QTNTGIRGTRGYVAPEWFK 694
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGE 1132
DV+SFGV L EL+ + + + L A R+ L+ +
Sbjct 695 NIGITSKVDVYSFGVILLELVCCRKNVELEVADEEQTILTYWANDCYRCGRIDLLVAGDD 754
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
K + C + E S RPT ++ +L + PS +
Sbjct 755 EAIFNIKKVERFVAVALWCLQEEPSMRPTMHKVMQMLDGAVQIPTPPDPSSY 806
Score = 204 bits (520), Expect = 3e-53, Method: Composition-based stats.
Identities = 71/406 (17%), Positives = 136/406 (33%), Gaps = 71/406 (17%)
Query 486 TVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCF 545
TV + S+ ++D + + G F S L L +L G C
Sbjct 430 TVLLKVPRSTNSPSMISSGSSKWKKDKKYWILGSSLFFGS-SVLVNFLLIFVLLFGTYCS 488
Query 546 SLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605
R SN L ++ +++ LG G VY+
Sbjct 489 ITSRKKTQLSQLPSN-----------SGLPSKIFTYRELEKATGGFHEVLGTGASGIVYK 537
Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV 665
G+L+ E + + +K ++ + F + Q
Sbjct 538 GQLQDECGTN-----------------------IAVKKIEKLQQEAQKEFLVEVQTIGQT 574
Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL 725
H +L + G C G E ++V E++ +G L+ +L H + ++ VA ++ L YL
Sbjct 575 FHRNLVRLLGFCNEGTEKLLVYEFMSNGSLNTFLF-NDTHPHWSLRVQVALGVSRGLLYL 633
Query 726 E---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIP 777
NK ++H ++ +NILL + K+SD G+ + +
Sbjct 634 HEECNKQIIHCDMKPQNILLD-------DNFVAKISDFGLAKLLPVNQTQTNTGIRGTRG 686
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP- 836
++APE +++ +D + FG LLE+ + + E+ +
Sbjct 687 YVAPEWFKNIG--ITSKVDVYSFGVILLELVCCRKNVELEVADEEQTILTYWANDCYRCG 744
Query 837 -----------------SCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ + CL EP+ RP+ +++
Sbjct 745 RIDLLVAGDDEAIFNIKKVERFVAVALWCLQEEPSMRPTMHKVMQM 790
>sp|Q9LFS4|NIK1_ARATH Protein NSP-INTERACTING KINASE 1 OS=Arabidopsis
thaliana OX=3702 GN=NIK1 PE=1 SV=1
Length=638
Score = 227 bits (578), Expect = 7e-62, Method: Composition-based stats.
Identities = 72/296 (24%), Positives = 125/296 (42%), Gaps = 20/296 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G +G V G +VAVK LK ++ E++++ H ++++
Sbjct 318 LGKGGYGNVYKGIL-----GDSTVVAVKRLKDGGALGGEIQFQTEVEMISLAVHRNLLRL 372
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ---H 1018
G C Q EK LV Y+ GS+ + + + + A G+ YLH Q
Sbjct 373 YGFCITQTEK--LLVYPYMSNGSVASRMKAKPVLDWSIRKRIAIGAARGLVYLHEQCDPK 430
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ A N+LLD+ +GDFGLAK + + V V APE L +
Sbjct 431 IIHRDVKAANILLDDYCEAVVGDFGLAKLLDHQDSH--VTTAVRGTVGHIAPEYLSTGQS 488
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGE--RL 1134
+DV+ FG+ L EL+T + + + ++ + +L L+++ +
Sbjct 489 SEKTDVFGFGILLLELVTGQRAFEFGKAANQKGVMLDWVKKIHQEKKLELLVDKELLKKK 548
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK--TVHEKYQ-GQAPSVFSVC 1187
+ E+ + C + RP ++ +L+ + EK++ Q S C
Sbjct 549 SYDEIELDEMVRVALLCTQYLPGHRPKMSEVVRMLEGDGLAEKWEASQRSDSVSKC 604
Score = 191 bits (486), Expect = 7e-50, Method: Composition-based stats.
Identities = 61/322 (19%), Positives = 112/322 (35%), Gaps = 66/322 (20%)
Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
NL + F + + + LG+G NVY+G L
Sbjct 296 NLRRFGFRELQIATNNFSSKNLLGKGGYGNVYKGIL------------------------ 331
Query 633 RGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
G V +K L + F ++S H +L ++G C+ E ++V Y+
Sbjct 332 -GDSTVVAVKRLKDGGALGGEIQFQTEVEMISLAVHRNLLRLYGFCITQTEKLLVYPYMS 390
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748
+G + ++ + + + + +A A L YL + ++H +V NILL A
Sbjct 391 NGSVASRMKA-KPVLDWSIRKRIAIGAARGLVYLHEQCDPKIIHRDVKAANILLDDYCEA 449
Query 749 EGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
+ D G+ ++ V + +APE L G + S D +GFG
Sbjct 450 V-------VGDFGLAKLLDHQDSHVTTAVRGTVGHIAPEYLSTGQS--SEKTDVFGFGIL 500
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE--------------------PSCPQLAT 843
LLE+ A ++ ++K ++ + ++
Sbjct 501 LLELVTGQRAFEFGKAANQKGVMLDWVKKIHQEKKLELLVDKELLKKKSYDEIELDEMVR 560
Query 844 LTSQCLTYEPTQRPSFRTILRD 865
+ C Y P RP ++R
Sbjct 561 VALLCTQYLPGHRPKMSEVVRM 582
>sp|Q9LX29|ACR4L_ARATH Serine/threonine-protein kinase-like protein
ACR4 OS=Arabidopsis thaliana OX=3702 GN=ACR4 PE=1 SV=1
Length=895
Score = 232 bits (591), Expect = 8e-62, Method: Composition-based stats.
Identities = 72/346 (21%), Positives = 138/346 (40%), Gaps = 20/346 (6%)
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+C + T+ +D +++P + K+ +G+G
Sbjct 463 RCSEND-TRSSKDSAFTKDNGKIRPDLDELQKRRRARVFTYEELEKAADGFKEESIVGKG 521
Query 907 HFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGC 965
F V G VAVK + + ++ + ++ E+D+L L H H++ G
Sbjct 522 SFSCVYKGVLR-----DGTTVAVKRAIMSSDKQKNSNEFRTELDLLSRLNHAHLLSLLGY 576
Query 966 CEDQGEKSLQLVMEYVPLGSLRDYLP------RHSIGLAQLLLFAQQICEGMAYLHA--- 1016
CE+ GE+ LV E++ GSL ++L + + + + A Q G+ YLH
Sbjct 577 CEECGER--LLVYEFMAHGSLHNHLHGKNKALKEQLDWVKRVTIAVQAARGIEYLHGYAC 634
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ + N+L+D + ++ DFGL+ + + E + + PE + +
Sbjct 635 PPVIHRDIKSSNILIDEEHNARVADFGLS-LLGPVDSGSPLAELPAGTLGYLDPEYYRLH 693
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
SDV+SFGV L E+L+ + + ++ A + + LL+ + P
Sbjct 694 YLTTKSDVYSFGVLLLEILSGRKAI-DMHYEEGNIVEWAVPLIKAGDINALLDPVLKHPS 752
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182
+ + + C RP+ + + L+ + G S
Sbjct 753 EIEALKRIVSVACKCVRMRGKDRPSMDKVTTALERALAQLMGNPSS 798
Score = 198 bits (503), Expect = 9e-51, Method: Composition-based stats.
Identities = 50/242 (21%), Positives = 91/242 (38%), Gaps = 45/242 (19%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+ S +G+G+ + VY+G LR G + V ++
Sbjct 512 FKEESIVGKGSFSCVYKGVLRD-----------------------GTTVAVKRAIMSSDK 548
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE----RG 704
+ F L+S+++H HL + G C E ++V E++ HG L L + +
Sbjct 549 QKNSNEFRTELDLLSRLNHAHLLSLLGYCEECGERLLVYEFMAHGSLHNHLHGKNKALKE 608
Query 705 HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
+ ++ +A Q A + YL ++H ++ NIL+ +++D G
Sbjct 609 QLDWVKRVTIAVQAARGIEYLHGYACPPVIHRDIKSSNILIDEE-------HNARVADFG 661
Query 762 VGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
+ L + +L PE + L+T D + FG LLEI +A
Sbjct 662 LSLLGPVDSGSPLAELPAGTLGYLDPEYYR--LHYLTTKSDVYSFGVLLLEILSGRKAID 719
Query 816 QS 817
Sbjct 720 MH 721
>sp|Q54DF2|MRKA_DICDI Probable serine/threonine-protein kinase
MARK-A OS=Dictyostelium discoideum OX=44689 GN=mrkA PE=3 SV=1
Length=1060
Score = 234 bits (596), Expect = 8e-62, Method: Composition-based stats.
Identities = 72/269 (27%), Positives = 116/269 (43%), Gaps = 28/269 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHII 960
+G G FGKV L + E VA+K + P+ ++E+ I++ L+H +II
Sbjct 114 TIGRGQFGKVKLGYHK---KIPNEKVAIKIINKGKLDPETLKMVQREVRIMKLLHHPNII 170
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019
+ E ++L L+MEY G + D++ H + +Q F QI + Y H++
Sbjct 171 RLYEVIE--TSRALYLIMEYAGEGEVMDFMIAHGVLTESQARTFFTQIVSAINYCHSKRA 228
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDL N+LLD +R +KI DFGL+ G ++ SP + +PE + ++
Sbjct 229 VHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGS---YLKTFCGSPT-YASPELILRKEYN 284
Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+ DVWS GV L+ L+T G V ++L P
Sbjct 285 GPSVDVWSMGVVLFVLVTGYLPFD--------------GDNYVELFQKILAGNY--TIPS 328
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIP 1167
E L+ + R T E +I
Sbjct 329 YLTHECKSLISRMLVVDPDKRATMEEIIN 357
Score = 173 bits (438), Expect = 1e-42, Method: Composition-based stats.
Identities = 44/282 (16%), Positives = 96/282 (34%), Gaps = 39/282 (14%)
Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651
+ +G+G V G + + +V +K+++ D
Sbjct 112 IKTIGRGQFGKVKLGYHK-----------------------KIPNEKVAIKIINKGKLDP 148
Query 652 A--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
+M + H ++ ++ V ++ EY G + ++ G + +
Sbjct 149 ETLKMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAH-GVLTES 207
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGA 766
Q+ SA++Y +K VH ++ N+LL + IK+ D G+
Sbjct 208 QARTFFTQIVSAINYCHSKRAVHRDLKPENLLLD-------CNRQIKIIDFGLSNVFTPG 260
Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EH 825
+ + +PE + + ++D W G L + G P + E +
Sbjct 261 SYLKTFCGSPTYASPELILRKEYN-GPSVDVWSMGVVL-FVLVTGYLPFDGDNYVELFQK 318
Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ +P + +L S+ L +P +R + I+
Sbjct 319 ILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPW 360
>sp|Q61846|MELK_MOUSE Maternal embryonic leucine zipper kinase
OS=Mus musculus OX=10090 GN=Melk PE=1 SV=2
Length=643
Score = 227 bits (578), Expect = 8e-62, Method: Composition-based stats.
Identities = 73/283 (26%), Positives = 123/283 (43%), Gaps = 26/283 (9%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
+Y + +G G F KV L C + TGEMVA+K + + K
Sbjct 1 MKDYDELLKYYELYETIGTGGFAKVKLAC----HVLTGEMVAIKIMDKNALGSDLPRVKT 56
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQ 1005
EID L++L H+HI + E + + + +V+EY P G L DY+ + + + + +
Sbjct 57 EIDALKSLRHQHICQLYHVLETKNK--IFMVLEYCPGGELFDYIISQDRLSEEETRVVFR 114
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
QI +AY+H+Q Y HRDL N+L D + +K+ DFGL +Y+ + +
Sbjct 115 QILSAVAYVHSQGYAHRDLKPENLLFDENHKLKLIDFGLCAKPKGNKDYHL--QTCCGSL 172
Query 1066 FWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+ APE ++ + +DVWS G+ LY L+ V+ L
Sbjct 173 AYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDD---------------NVMAL 217
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + RG + P L++ + + R + NL+
Sbjct 218 YKKIMRG-KYEVPKWLSPSSILLLQQMLQVDPKKRISMRNLLN 259
Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats.
Identities = 51/318 (16%), Positives = 104/318 (33%), Gaps = 41/318 (13%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647
+G G V + G V +K++D +
Sbjct 12 ELYETIGTGGFAKVKLACHVLTGEM------------------------VAIKIMDKNAL 47
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
D+ + + H H+ ++ V + MV EY G L ++ +
Sbjct 48 GSDLPR-VKTEIDALKSLRHQHICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSE 106
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----- 762
++ V +Q+ SA++Y+ ++ H ++ N+L + +KL D G+
Sbjct 107 EETRV-VFRQILSAVAYVHSQGYAHRDLKPENLLFDE-------NHKLKLIDFGLCAKPK 158
Query 763 GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
G + + + APE + G + L + D W G L + +
Sbjct 159 GNKDYHLQTCCGSLAYAAPELIQGKSY-LGSEADVWSMGILLYVLMCGFLPFDDDNVMAL 217
Query 823 KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
+ + ++ +P+ P L Q L +P +R S R +L +Q ++
Sbjct 218 YKKIMRGKYEVPKWLSPSSILLLQQMLQVDPKKRISMRNLLNHPWVMQDYSCPVEWQSKT 277
Query 883 DSPASDPTVFHKRYLKKI 900
D + +
Sbjct 278 PLTHLDEDCVTELSVHHR 295
>sp|Q93VD3|CIPKN_ARATH CBL-interacting serine/threonine-protein
kinase 23 OS=Arabidopsis thaliana OX=3702 GN=CIPK23 PE=1 SV=1
Length=482
Score = 223 bits (567), Expect = 8e-62, Method: Composition-based stats.
Identities = 61/270 (23%), Positives = 114/270 (42%), Gaps = 27/270 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959
LGEG F KV N G+ VA+K + + +++ + K+EI ++ + H ++
Sbjct 36 TLGEGTFAKVKF----ARNVENGDNVAIKVIDKEKVLKNKMIAQIKREISTMKLIKHPNV 91
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018
I+ + + + V+E+V G L D + + + + + QQ+ + Y H++
Sbjct 92 IRMFEVMASKTK--IYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRG 149
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N+LLD + +K+ DFGL+ + E + +P + APE + +
Sbjct 150 VYHRDLKPENLLLDANGALKVSDFGLSALPQQVREDGLLHTTCGTPN-YVAPEVINNKGY 208
Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+D+WS GV L+ L+ + + L + + + E P
Sbjct 209 DGAKADLWSCGVILFVLMAGYLPFED---------------SNLTSLYKKIFKAE-FTCP 252
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L+K + + R TF +I
Sbjct 253 PWFSASAKKLIKRILDPNPATRITFAEVIE 282
Score = 169 bits (428), Expect = 1e-43, Method: Composition-based stats.
Identities = 49/290 (17%), Positives = 88/290 (30%), Gaps = 42/290 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ LG+GT V R G V +KV+D
Sbjct 30 KYELGRTLGEGTFAKVKFARNVENGDN------------------------VAIKVIDKE 65
Query 648 ---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ + S M + H ++ + V + V E+V G L + G
Sbjct 66 KVLKNKMIAQIKREISTMKLIKHPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSN-G 124
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763
+ QQL +A+ Y ++ + H ++ N+LL + +K+SD G+
Sbjct 125 RLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLLD-------ANGALKVSDFGLSA 177
Query 764 -----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
++APE + D W G L + S
Sbjct 178 LPQQVREDGLLHTTCGTPNYVAPEVINNKGYD-GAKADLWSCGVILFVLMAGYLPFEDSN 236
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
S + ++ + P L + L P R +F ++ +
Sbjct 237 LTSLYKKIFKAEFTCPPWFSASAKKLIKRILDPNPATRITFAEVIENEWF 286
>sp|Q9NB31|CST1_CAEEL Serine/threonine-protein kinase cst-1 OS=Caenorhabditis
elegans OX=6239 GN=cst-1 PE=1 SV=1
Length=497
Score = 223 bits (568), Expect = 8e-62, Method: Composition-based stats.
Identities = 62/262 (24%), Positives = 114/262 (44%), Gaps = 31/262 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V + + +G ++A+K + D Q +EI I++ ++++K
Sbjct 40 KLGEGSYGSV----HKAIHRESGHVLAIKKVPVDTDLQ---EIIKEISIMQQCKSKYVVK 92
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D + R + ++ + +G+ YLH
Sbjct 93 YYGSYFKHSD--LWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKK 150
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ D + K+ DFG+A + + R FW APE ++E +
Sbjct 151 IHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIEEIGYD 207
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL--ERGERLPRP 1137
+D+WS G+T E+ + +R ++ + +P
Sbjct 208 TKADIWSLGITAIEMAEGRPP---------------YSDIHPMRAIFMIPTKPPPTFKKP 252
Query 1138 DKCPCEVYHLMKNCWETEASFR 1159
++ E +++C + R
Sbjct 253 EEWSSEFNDFIRSCLIKKPEER 274
Score = 194 bits (493), Expect = 6e-52, Method: Composition-based stats.
Identities = 58/338 (17%), Positives = 109/338 (32%), Gaps = 44/338 (13%)
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615
+++ S L + ++ ++ + LG+G+ +V++ R G
Sbjct 2 PPSTDSSRRNSEEGSSDGFKLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHRESGHVL 61
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675
+K + P D+ + S+M Q ++ +G
Sbjct 62 ------------------------AIKKV-PVDTDLQ-EIIKEISIMQQCKSKYVVKYYG 95
Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNV 735
+ + +V EY G + +R R + V + L YL + +H ++
Sbjct 96 SYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDI 155
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSL 791
NILL G+A KL+D GV R + W+APE +
Sbjct 156 KAGNILLNTDGIA-------KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIG--Y 206
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQ 847
T D W G T +E+ +G P P + + PE +
Sbjct 207 DTKADIWSLGITAIEMA-EGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRS 265
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885
CL +P +R + + + + D+
Sbjct 266 CLIKKPEERKTALRLCEHTFIKNAPGCDIMQLMIQDAQ 303
>sp|Q54H05|KINY_DICDI Probable serine/threonine-protein kinase
kinY OS=Dictyostelium discoideum OX=44689 GN=kinY PE=2 SV=1
Length=579
Score = 225 bits (574), Expect = 9e-62, Method: Composition-based stats.
Identities = 62/289 (21%), Positives = 125/289 (43%), Gaps = 38/289 (13%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959
+G G +G V ++ VA+K ++ + ++ K+E+ +L+ + H +I
Sbjct 37 SIGSGAYGIVYRGTLFNSD------VAIKKIQNEKSEKNEFIKYLKREVAVLKNIQHPNI 90
Query 960 IKYKGCCEDQ-----------GEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQ 1006
+++ G + S +V EY+ G+L + + + + + +
Sbjct 91 VQFIGVYYEPLASPSLVNRLLNSSSTWIVTEYIGGGNLHERIKDTKKDFPIELRIKLSLD 150
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLV---KIGDFGLAKAVPEGHEYYRVREDGDS 1063
I MAYLH++ I RDL ++N+L+D+ K+ DFG A+ + + + R +
Sbjct 151 IALAMAYLHSRDIIFRDLKSKNILIDDSSSPIRGKVCDFGFARILNKKQQGNRHLSICGT 210
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
APE + ++ + D++SFGV L E++ S+ + +G +
Sbjct 211 DSI-MAPELILGMEYDESVDIFSFGVVLLEMILRKKVSKV----------LERGPQSAFE 259
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ + R PD P L +C + + RP F ++I +LK +
Sbjct 260 IDQ---DSARQLIPDDIPVLYSDLALDCIKYQPEERPNFSHIIHVLKQL 305
Score = 191 bits (486), Expect = 3e-50, Method: Composition-based stats.
Identities = 55/311 (18%), Positives = 111/311 (36%), Gaps = 57/311 (18%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+D K++ +G G VY G L V +K
Sbjct 27 IDIKDLKVGESIGSGAYGIVYRGTLFNSD--------------------------VAIKK 60
Query 644 L---DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG-------------PENIMVT 687
+ ++ +++ + H ++ GV +VT
Sbjct 61 IQNEKSEKNEFIKYLKREVAVLKNIQHPNIVQFIGVYYEPLASPSLVNRLLNSSSTWIVT 120
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
EY+ G L ++ + P+ ++ ++ +A A++YL +++++ ++ +NIL+
Sbjct 121 EYIGGGNLHERIKDTKKDFPIELRIKLSLDIALAMAYLHSRDIIFRDLKSKNILID---- 176
Query 748 AEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
+ K+ D G ++ +APE + G ++D + FG
Sbjct 177 DSSSPIRGKVCDFGFARILNKKQQGNRHLSICGTDSIMAPELILGM--EYDESVDIFSFG 234
Query 802 ATLLEICFDGEAPLQ-SRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPS 858
LLE+ + R P Q R +P+ + L C+ Y+P +RP+
Sbjct 235 VVLLEMILRKKVSKVLERGPQSAFEIDQDSARQLIPDDIPVLYSDLALDCIKYQPEERPN 294
Query 859 FRTILRDLTRL 869
F I+ L +L
Sbjct 295 FSHIIHVLKQL 305
>sp|Q6IP06|STK3_XENLA Serine/threonine-protein kinase 3 OS=Xenopus
laevis OX=8355 GN=stk3 PE=2 SV=1
Length=493
Score = 223 bits (567), Expect = 9e-62, Method: Composition-based stats.
Identities = 65/268 (24%), Positives = 110/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V + + +G++VA+K + + Q +EI I++ +++K
Sbjct 31 KLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQ---EIIKEISIMQQCDSHYVVK 83
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ + +G+ YLH
Sbjct 84 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILRSTLKGLEYLHFMRK 141
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 142 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 198
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 199 CVADIWSLGITSIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 245
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
E +K C R T L+
Sbjct 246 WTDEFTDFVKKCLVKNPEQRATATQLLQ 273
Score = 196 bits (497), Expect = 2e-52, Method: Composition-based stats.
Identities = 57/312 (18%), Positives = 100/312 (32%), Gaps = 44/312 (14%)
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
M + LS+ S + ++ L LG+G+ +V++ + G
Sbjct 1 MEQPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQ---------- 50
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
V +K + + S+M Q ++ +G + +
Sbjct 51 --------------VVAIKQVPVESD--LQEIIKEISIMQQCDSHYVVKYYGSYFKNTDL 94
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+V EY G + +R + + + L YL +H ++ NILL
Sbjct 95 WIVMEYCGAGSVSDIIRLRNKTLTEDEIATILRSTLKGLEYLHFMRKIHRDIKAGNILLN 154
Query 744 RLGLAEGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWG 799
G KL+D GV R + W+APE + + D W
Sbjct 155 TEG-------HAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWS 205
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQ 855
G T +E+ +G+ P P R PE + +CL P Q
Sbjct 206 LGITSIEMA-EGKPPYADIHPMRAIFMIPTNPPPTFRKPELWTDEFTDFVKKCLVKNPEQ 264
Query 856 RPSFRTILRDLT 867
R + +L+
Sbjct 265 RATATQLLQHPF 276
>sp|Q7XR88|STRK1_ORYSJ Salt tolerance receptor-like cytoplasmic
kinase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=STRK1
PE=1 SV=2
Length=361
Score = 218 bits (556), Expect = 9e-62, Method: Composition-based stats.
Identities = 66/281 (23%), Positives = 110/281 (39%), Gaps = 23/281 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G F V L + G AVK + ++QE+++L +L H HI++
Sbjct 73 IGHGGFSTVYLASLSSSRLG-----AVKV--HCSSERLHRAFRQELEVLLSLRHPHIVRL 125
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------IGLAQLLLFAQQICEGMAYL 1014
G C+++ E LV EY P G L + L + A+ + A Q+ + YL
Sbjct 126 LGYCDERDEG--VLVFEYAPNGDLHERLHCSEVAGGVASVLPWARRVAIAFQVAMALEYL 183
Query 1015 HAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKA-VPEGHEYYRVREDGDSPVFWYAP 1070
H IH D+ A NVLLD + K+ DFG A + P
Sbjct 184 HESRHPAVIHGDIKASNVLLDANMNAKLCDFGFAHVGFSATVGCRPSARAVMGSPGYVDP 243
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
++ SDV+SFGV L EL+T ++ L ++ ++ ++++R
Sbjct 244 HLIRSGVATKKSDVYSFGVLLLELVTGKEAVCR--DTGRRLTAAVGPMLSEGKVADVVDR 301
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ L C RP+ +++ L+
Sbjct 302 RLGGEHDGAEAAVMAELAMQCIGDSPGLRPSMADVVRALQE 342
Score = 182 bits (461), Expect = 5e-49, Method: Composition-based stats.
Identities = 63/301 (21%), Positives = 99/301 (33%), Gaps = 66/301 (22%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
+G G + VY L G +KV S +
Sbjct 71 RVIGHGGFSTVYLASLSSSRLG-------------------------AVKV-HCSSERLH 104
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER------GHV 706
AF + ++ + H H+ + G C E ++V EY +G L L +
Sbjct 105 RAFRQELEVLLSLRHPHIVRLLGYCDERDEGVLVFEYAPNGDLHERLHCSEVAGGVASVL 164
Query 707 PMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
P A ++ +A Q+A AL YL ++HG++ N+LL + KL D G
Sbjct 165 PWARRVAIAFQVAMALEYLHESRHPAVIHGDIKASNVLLD-------ANMNAKLCDFGFA 217
Query 764 LGALSRE--------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
S + ++ P + G + D + FG LLE+ EA
Sbjct 218 HVGFSATVGCRPSARAVMGSPGYVDPHLIRSGVA--TKKSDVYSFGVLLLELVTGKEAVC 275
Query 816 Q----------SRSPSEKEHFYQRQHRLPEPSC----PQLATLTSQCLTYEPTQRPSFRT 861
+ SE + RL +A L QC+ P RPS
Sbjct 276 RDTGRRLTAAVGPMLSEGKVADVVDRRLGGEHDGAEAAVMAELAMQCIGDSPGLRPSMAD 335
Query 862 I 862
+
Sbjct 336 V 336
>sp|A2XW02|STRK1_ORYSI Salt tolerance receptor-like cytoplasmic
kinase 1 OS=Oryza sativa subsp. indica OX=39946 GN=OsI_16820
PE=2 SV=1
Length=361
Score = 218 bits (556), Expect = 9e-62, Method: Composition-based stats.
Identities = 66/281 (23%), Positives = 110/281 (39%), Gaps = 23/281 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G F V L + G AVK + ++QE+++L +L H HI++
Sbjct 73 IGHGGFSTVYLASLSSSRLG-----AVKV--HCSSERLHRAFRQELEVLLSLRHPHIVRL 125
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------IGLAQLLLFAQQICEGMAYL 1014
G C+++ E LV EY P G L + L + A+ + A Q+ + YL
Sbjct 126 LGYCDERDEG--VLVFEYAPNGDLHERLHCSEVAGGVASVLPWARRVAIAFQVAMALEYL 183
Query 1015 HAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKA-VPEGHEYYRVREDGDSPVFWYAP 1070
H IH D+ A NVLLD + K+ DFG A + P
Sbjct 184 HESRHPAVIHGDIKASNVLLDANMNAKLCDFGFAHVGFSATVGCRPSARAVMGSPGYVDP 243
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
++ SDV+SFGV L EL+T ++ L ++ ++ ++++R
Sbjct 244 HLIRSGVATKKSDVYSFGVLLLELVTGKEAVCR--DTGRRLTAAVGPMLSEGKVADVVDR 301
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ L C RP+ +++ L+
Sbjct 302 RLGGEHDGAEAAVMAELAMQCIGDSPGLRPSMADVVRALQE 342
Score = 182 bits (461), Expect = 5e-49, Method: Composition-based stats.
Identities = 63/301 (21%), Positives = 99/301 (33%), Gaps = 66/301 (22%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
+G G + VY L G +KV S +
Sbjct 71 RVIGHGGFSTVYLASLSSSRLG-------------------------AVKV-HCSSERLH 104
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER------GHV 706
AF + ++ + H H+ + G C E ++V EY +G L L +
Sbjct 105 RAFRQELEVLLSLRHPHIVRLLGYCDERDEGVLVFEYAPNGDLHERLHCSEVAGGVASVL 164
Query 707 PMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
P A ++ +A Q+A AL YL ++HG++ N+LL + KL D G
Sbjct 165 PWARRVAIAFQVAMALEYLHESRHPAVIHGDIKASNVLLD-------ANMNAKLCDFGFA 217
Query 764 LGALSRE--------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
S + ++ P + G + D + FG LLE+ EA
Sbjct 218 HVGFSATVGCRPSARAVMGSPGYVDPHLIRSGVA--TKKSDVYSFGVLLLELVTGKEAVC 275
Query 816 Q----------SRSPSEKEHFYQRQHRLPEPSC----PQLATLTSQCLTYEPTQRPSFRT 861
+ SE + RL +A L QC+ P RPS
Sbjct 276 RDTGRRLTAAVGPMLSEGKVADVVDRRLGGEHDGAEAAVMAELAMQCIGDSPGLRPSMAD 335
Query 862 I 862
+
Sbjct 336 V 336
>sp|A9TXT1|CERK1_PHYPA Chitin elicitor receptor kinase 1 OS=Physcomitrium
patens OX=3218 GN=CERK1 PE=2 SV=2
Length=640
Score = 227 bits (578), Expect = 9e-62, Method: Composition-based stats.
Identities = 66/296 (22%), Positives = 114/296 (39%), Gaps = 43/296 (15%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G F V + +A+K + C + E+ +L ++H ++++
Sbjct 335 KIGQGGFASVYYGVIR------DQKLAIKKMTLQCT----KEFLAELQVLTNVHHTNLVQ 384
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYLH 1015
G C SL LV EY+ G+L +L R + Q + G+ Y+H
Sbjct 385 LIGYCTTN---SLFLVYEYIENGTLDHHLRRRKSDDKPPLSWLQRVQICLDSARGLEYIH 441
Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
YIHRD+ + N+LLD++ K+ DFGLAK EG + PE
Sbjct 442 EHTKPTYIHRDIKSANILLDDNFRAKVADFGLAKLAEEG-----TGTGIVGTFGYMPPEY 496
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHC---------DSSQSPPTKFLELIGIAQGQMTVLR 1123
+ DV++FGV L+E+++ ++ Q P + E + VL
Sbjct 497 ALYGEVSPKLDVYAFGVVLFEIISGRVAISSALPSENDQQSPAQNRESRTLTSFFEPVLN 556
Query 1124 -------LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
L + ++ ++ L + C RPT + L T+
Sbjct 557 DPDGKTLLPKCIDPALNGEYSLDAVWKMAQLARRCTHQSPDMRPTMRFAVVQLMTL 612
Score = 206 bits (523), Expect = 1e-54, Method: Composition-based stats.
Identities = 66/344 (19%), Positives = 116/344 (34%), Gaps = 61/344 (18%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ +GQG +VY G +R + ++ +K +
Sbjct 326 ATDNFSLAKKIGQGGFASVYYGVIR--------------------------DQKLAIKKM 359
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
F +++ V HT+L + G C +V EY+E+G LD LRR +
Sbjct 360 ---TLQCTKEFLAELQVLTNVHHTNLVQLIGYCTTNS-LFLVYEYIENGTLDHHLRRRKS 415
Query 705 --HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKL 757
P++W ++ + A L Y+ +H ++ NILL + K+
Sbjct 416 DDKPPLSWLQRVQICLDSARGLEYIHEHTKPTYIHRDIKSANILLD-------DNFRAKV 468
Query 758 SDPGVGLGALSREER--VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
+D G+ A V ++ PE G +S +D + FG L EI G +
Sbjct 469 ADFGLAKLAEEGTGTGIVGTFGYMPPEYALYG--EVSPKLDVYAFGVVLFEIIS-GRVAI 525
Query 816 QSRSPSEKEHFYQRQHR---------LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
S PSE + Q+R P + P TL +C+ ++
Sbjct 526 SSALPSENDQQSPAQNRESRTLTSFFEPVLNDPDGKTLLPKCIDP---ALNGEYSLDAVW 582
Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910
Q + + V ++ G+F +
Sbjct 583 KMAQLARRCTHQSPDMRPTMRFAVVQLMTLASVTQEWDVGYFSR 626
>sp|P34908|BRAF_COTJA Serine/threonine-protein kinase B-raf OS=Coturnix
japonica OX=93934 GN=BRAF PE=2 SV=1
Length=807
Score = 230 bits (586), Expect = 9e-62, Method: Composition-based stats.
Identities = 76/306 (25%), Positives = 130/306 (42%), Gaps = 31/306 (10%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+ + +SD + + +G G FG V + VAVK L
Sbjct 475 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-------DVAVKMLNV 527
Query 935 DC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991
PQ +K E+ +LR H +I+ + G + L +V ++ SL +L
Sbjct 528 TAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY---STKPQLAIVTQWCEGSSLYHHLHII 584
Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
+ +L+ A+Q +GM YLHA+ IHRDL + N+ L D VKIGDFGLA
Sbjct 585 ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRW 644
Query 1052 HEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQ--SPPT 1106
++ E + W APE ++ + + + SDV++FG+ LYEL+T +
Sbjct 645 SGSHQF-EQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRD 703
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ + ++G + ++ CP + LM C + + RP F ++
Sbjct 704 QIIFMVGRGYLSPDLSKVR------------SNCPKAMKRLMAECLKKKRDERPLFPQIL 751
Query 1167 PILKTV 1172
++ +
Sbjct 752 ASIELL 757
Score = 225 bits (574), Expect = 4e-60, Method: Composition-based stats.
Identities = 71/379 (19%), Positives = 131/379 (35%), Gaps = 57/379 (15%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSF-HRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
P P R +TL S + +IT +G G+ VY+G+ +
Sbjct 460 PGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD 519
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSHTH 669
V +K+L+ + AF ++ + H +
Sbjct 520 ---------------------------VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVN 552
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729
+ G + P+ +VT++ E L L M + +A+Q A + YL K+
Sbjct 553 ILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKS 611
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPEC 783
++H ++ NI L +K+ D G+ G+ E+ I W+APE
Sbjct 612 IIHRDLKSNNIFLHE-------DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEV 664
Query 784 LPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP------ 836
+ N S D + FG L E+ G+ P + + ++ F + L
Sbjct 665 IRMQDKNPYSFQSDVYAFGIVLYELM-TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRS 723
Query 837 SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL----TRLQPHNLADVLTVNPDSPASDPTV 891
+CP+ + L ++CL + +RP F IL + L + + +
Sbjct 724 NCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDF 783
Query 892 FHKRYLKKIRDLGEGHFGK 910
+ G +G+
Sbjct 784 SLYACASPKTPIQAGGYGE 802
>sp|O81292|LRK43_ARATH L-type lectin-domain containing receptor
kinase IV.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK43 PE=2
SV=1
Length=674
Score = 228 bits (580), Expect = 9e-62, Method: Composition-based stats.
Identities = 86/384 (22%), Positives = 146/384 (38%), Gaps = 28/384 (7%)
Query 798 WGF---GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854
W F G T + P+ + FY ++R+P L +L + + +
Sbjct 261 WSFMVKGKTAPPLTLSKVPKFPRVGPTSLQRFY--KNRMP------LFSLLLIPVLFVVS 312
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
R I+R + + + + K LG G FG+V
Sbjct 313 LIFLVRFIVRRRRKFAEEFEDWETEFGKNRLRFKDLYYATKGFKDKDLLGSGGFGRV--- 369
Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
Y T + +AVK + + Q + EI + + H +++ G C + E L
Sbjct 370 -YRGVMPTTKKEIAVKRVSNE-SRQGLKEFVAEIVSIGRMSHRNLVPLLGYCRRRDE--L 425
Query 975 QLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARN 1028
LV +Y+P GSL YL P ++ Q + G+ YLH + IHRD+ A N
Sbjct 426 LLVYDYMPNGSLDKYLYDCPEVTLDWKQRFNVIIGVASGLFYLHEEWEQVVIHRDIKASN 485
Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088
VLLD + ++GDFGLA+ G + R + AP+ ++ + A+DV++FG
Sbjct 486 VLLDAEYNGRLGDFGLARLCDHGSDPQTTR--VVGTWGYLAPDHVRTGRATTATDVFAFG 543
Query 1089 VTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
V L E+ + L+ G + + + + V
Sbjct 544 VLLLEVACGRRPIEIEIESDESVLLVDSVFGFWIEGNILDATDPNLGSVYDQREVETVLK 603
Query 1147 LMKNCWETEASFRPTFENLIPILK 1170
L C ++ RPT ++ L+
Sbjct 604 LGLLCSHSDPQVRPTMRQVLQYLR 627
Score = 199 bits (505), Expect = 4e-52, Method: Composition-based stats.
Identities = 59/304 (19%), Positives = 102/304 (34%), Gaps = 52/304 (17%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
K LG G VY G + + + +K +
Sbjct 351 ATKGFKDKDLLGSGGFGRVYRGVM------------------------PTTKKEIAVKRV 386
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ER 703
F + ++SH +L + G C R E ++V +Y+ +G LD +L
Sbjct 387 SNESRQGLKEFVAEIVSIGRMSHRNLVPLLGYCRRRDELLLVYDYMPNGSLDKYLYDCPE 446
Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLA-RLGLAEGTSPFIKLSD 759
+ + V +AS L YL + ++H ++ N+LL G +L D
Sbjct 447 VTLDWKQRFNVIIGVASGLFYLHEEWEQVVIHRDIKASNVLLDAEYNGRLGDFGLARLCD 506
Query 760 PGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
G V +LAP+ + G +TA D + FG LLE+
Sbjct 507 HG---SDPQTTRVVGTWGYLAPDHVRTGRA--TTATDVFAFGVLLLEVACGRRPIEIEIE 561
Query 820 PSEKEHF------YQRQHRLPEPSCPQLATLTSQ------------CLTYEPTQRPSFRT 861
E + + + + + P L ++ Q C +P RP+ R
Sbjct 562 SDESVLLVDSVFGFWIEGNILDATDPNLGSVYDQREVETVLKLGLLCSHSDPQVRPTMRQ 621
Query 862 ILRD 865
+L+
Sbjct 622 VLQY 625
>sp|Q5ZJK4|STK4_CHICK Serine/threonine-protein kinase 4 OS=Gallus
gallus OX=9031 GN=STK4 PE=2 SV=1
Length=486
Score = 222 bits (566), Expect = 1e-61, Method: Composition-based stats.
Identities = 66/268 (25%), Positives = 108/268 (40%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V + + TG++VA+K + + Q +EI I++ H++K
Sbjct 34 KLGEGSYGSV----FKAIHKETGQVVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 86
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH
Sbjct 87 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEEEIATIVQSTLKGLEYLHFMRK 144
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW AP ++E +
Sbjct 145 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPGVIQEIGYN 201
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 202 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 248
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+K C R T L+
Sbjct 249 WSDAFTDFVKQCLVKSPEQRATAIQLLQ 276
Score = 194 bits (494), Expect = 4e-52, Method: Composition-based stats.
Identities = 57/300 (19%), Positives = 95/300 (32%), Gaps = 44/300 (15%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L + S + ++ L LG+G+ +V++ + G
Sbjct 16 LDEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKETGQ---------------------- 53
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K + + S+M Q H+ +G + + +V EY G +
Sbjct 54 --VVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 109
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + Q L YL +H ++ NILL G
Sbjct 110 SDIIRLRNKTLTEEEIATIVQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 162
Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL+D GV R + W+AP + + D W G T +E+ +G
Sbjct 163 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPGVIQEIG--YNCVADIWSLGITAIEMA-EG 219
Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P P R PE QCL P QR + +L+
Sbjct 220 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDAFTDFVKQCLVKSPEQRATAIQLLQHPF 279
>sp|Q13188|STK3_HUMAN Serine/threonine-protein kinase 3 OS=Homo
sapiens OX=9606 GN=STK3 PE=1 SV=2
Length=491
Score = 223 bits (567), Expect = 1e-61, Method: Composition-based stats.
Identities = 64/268 (24%), Positives = 110/268 (41%), Gaps = 27/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG +G V + + +G++VA+K + + Q +EI I++ +++K
Sbjct 32 KLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQ---EIIKEISIMQQCDSPYVVK 84
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Y G + L +VMEY GS+ D L ++ ++ + +G+ YLH
Sbjct 85 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRK 142
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E +
Sbjct 143 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 199
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+D+WS G+T E+ + I R +P+
Sbjct 200 CVADIWSLGITSIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 246
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ +K C R T L+
Sbjct 247 WSDDFTDFVKKCLVKNPEQRATATQLLQ 274
Score = 197 bits (501), Expect = 6e-53, Method: Composition-based stats.
Identities = 56/307 (18%), Positives = 98/307 (32%), Gaps = 44/307 (14%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
+ LS+ S + ++ L LG+G+ +V++ + G
Sbjct 7 PKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQ--------------- 51
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
V +K + + S+M Q ++ +G + + +V E
Sbjct 52 ---------VVAIKQVPVESD--LQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVME 100
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
Y G + +R + + + L YL +H ++ NILL G
Sbjct 101 YCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-- 158
Query 749 EGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
KL+D GV R + W+APE + + D W G T
Sbjct 159 -----HAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITS 211
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
+E+ +G+ P P R PE +CL P QR +
Sbjct 212 IEMA-EGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATAT 270
Query 861 TILRDLT 867
+L+
Sbjct 271 QLLQHPF 277
>sp|Q9LPQ3|M2K7_ARATH Mitogen-activated protein kinase kinase
7 OS=Arabidopsis thaliana OX=3702 GN=MKK7 PE=1 SV=1
Length=307
Score = 216 bits (550), Expect = 1e-61, Method: Composition-based stats.
Identities = 75/271 (28%), Positives = 120/271 (44%), Gaps = 26/271 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG G G V Y + TGE+ A+K++ D P +E++ILR +++
Sbjct 49 HVLGRGSSGIV----YKVHHKTTGEIYALKSVNGDMSPAFTRQLAREMEILRRTDSPYVV 104
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ +G E + ++MEY+ G+L R ++ QL F++QI +G++YLH+ +
Sbjct 105 RCQGIFEKPIVGEVSILMEYMDGGNLESL--RGAVTEKQLAGFSRQILKGLSYLHSLKIV 162
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE----CLKEY 1076
HRD+ N+LL++ VKI DFG++K + +Y + +PE E
Sbjct 163 HRDIKPANLLLNSRNEVKIADFGVSKIITRSLDY---CNSYVGTCAYMSPERFDSAAGEN 219
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
YA D+WSFGV + EL + QGQ + PR
Sbjct 220 SDVYAGDIWSFGVMILELFVGHFPL------------LPQGQRPDWATLMCVVCFGEPPR 267
Query 1137 -PDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
P+ C E + C E+S R T L+
Sbjct 268 APEGCSDEFRSFVDCCLRKESSERWTASQLL 298
Score = 169 bits (427), Expect = 4e-45, Method: Composition-based stats.
Identities = 62/322 (19%), Positives = 110/322 (34%), Gaps = 58/322 (18%)
Query 569 ASPRTLNLSQLSF---------HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEG 619
P +++L SF + + ++ +L LG+G+ VY+ + G +
Sbjct 16 VPPLSVHLPWFSFASSTAPVINNGISASDVEKLHVLGRGSSGIVYKVHHKTTGEIYALKS 75
Query 620 KMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR 679
D P ++ + ++ G+ +
Sbjct 76 VNGDMSPAF-----------------------TRQLAREMEILRRTDSPYVVRCQGIFEK 112
Query 680 G--PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737
E ++ EY++ G L+ RG V ++Q+ LSYL + +VH ++
Sbjct 113 PIVGEVSILMEYMDGGNLESL----RGAVTEKQLAGFSRQILKGLSYLHSLKIVHRDIKP 168
Query 738 RNILLARLGLAEGTSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPG--GANSL 791
N+LL +K++D GV V +++PE G NS
Sbjct 169 ANLLLNSRNE-------VKIADFGVSKIITRSLDYCNSYVGTCAYMSPERFDSAAGENSD 221
Query 792 STAMDKWGFGATLLEICFDGEAP--LQSRSPSEKEHFYQ----RQHRLPEPSCPQLATLT 845
A D W FG +LE+ F G P Q + P R PE + +
Sbjct 222 VYAGDIWSFGVMILEL-FVGHFPLLPQGQRPDWATLMCVVCFGEPPRAPEGCSDEFRSFV 280
Query 846 SQCLTYEPTQRPSFRTILRDLT 867
CL E ++R + +L
Sbjct 281 DCCLRKESSERWTASQLLGHPF 302
>sp|A0A078CGE6|M3KE1_BRANA MAP3K epsilon protein kinase 1 OS=Brassica
napus OX=3708 GN=M3KE1 PE=1 SV=1
Length=1299
Score = 234 bits (598), Expect = 1e-61, Method: Composition-based stats.
Identities = 74/294 (25%), Positives = 132/294 (45%), Gaps = 28/294 (10%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ S + ++G+G +G+V + + G+ VA+K + +
Sbjct 1 MARQMTSSQFHKSKTLDNKYMLGDEIGKGAYGRVYIG----LDLENGDFVAIKQVSLENI 56
Query 938 PQHR-SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996
Q + QEID+L+ L H++I+KY G + + L +++EYV GSL + + + G
Sbjct 57 VQEDLNTIMQEIDLLKNLNHKNIVKYLGSL--KTKTHLHIILEYVENGSLANIIKPNKFG 114
Query 997 ---LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ + ++ Q+ EG+ YLH Q IHRD+ N+L + LVK+ DFG+A + E
Sbjct 115 PFPESLVTVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGLVKLADFGVATKLNEAD- 173
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
+W APE ++ ASD+WS G T+ ELLT
Sbjct 174 --VNTHSVVGTPYWMAPEVIEMSGVCAASDIWSVGCTVIELLTCVPPYYD---------- 221
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
Q + R+ + + P PD ++ ++ C++ ++ RP + L+
Sbjct 222 -LQPMPALFRIVQ----DDSPPIPDSLSPDITDFLRQCFKKDSRQRPDAKTLLS 270
Score = 203 bits (517), Expect = 7e-52, Method: Composition-based stats.
Identities = 61/305 (20%), Positives = 107/305 (35%), Gaps = 43/305 (14%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
R + SQ + + +G+G VY G G
Sbjct 3 RQMTSSQFHKSKTLDNKYMLGDEIGKGAYGRVYIGLDLENGDF----------------- 45
Query 632 DRGQELRVVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
V +K + + + + L+ ++H ++ G ++ EY
Sbjct 46 -------VAIKQVSLENIVQEDLNTIMQEIDLLKNLNHKNIVKYLGSLKTKTHLHIILEY 98
Query 690 VEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
VE+G L ++ + G P + V Q+ L YL + ++H ++ G NIL + GL
Sbjct 99 VENGSLANIIKPNKFGPFPESLVTVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGL- 157
Query 749 EGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+KL+D GV ++ V W+APE + + + A D W G T+
Sbjct 158 ------VKLADFGVATKLNEADVNTHSVVGTPYWMAPEVIEM--SGVCAASDIWSVGCTV 209
Query 805 LEICFDGEAPLQSRSPSEKEH--FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
+E+ P P +P+ P + QC + QRP +T+
Sbjct 210 IELLTC-VPPYYDLQPMPALFRIVQDDSPPIPDSLSPDITDFLRQCFKKDSRQRPDAKTL 268
Query 863 LRDLT 867
L
Sbjct 269 LSHPW 273
>sp|A9RVK2|M3K1B_PHYPA Mitogen-activated protein kinase kinase
kinase 1b OS=Physcomitrium patens OX=3218 GN=MEKK1b PE=2 SV=2
Length=764
Score = 229 bits (584), Expect = 1e-61, Method: Composition-based stats.
Identities = 70/276 (25%), Positives = 119/276 (43%), Gaps = 31/276 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD----CGPQHRSGWKQEIDILR 952
K +G G FG V D G AVK + G + + EI +L
Sbjct 431 WFKGDFIGSGTFGSVYEGI-----DNNGMFFAVKEVSLKDQGKVGQEAIKQLEHEIALLS 485
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
+ H +I++Y G ++ ++ L + +E V GSL ++ Q+ + +QI G+
Sbjct 486 DIQHPNIVQYLG--TERDDEKLYIFLELVSKGSLASLYKKYYFVYDQVRAYTKQILSGLK 543
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
YLH + IHRD+ N+L+D + +VK+ DFG+AK V + + + W APE
Sbjct 544 YLHDRKIIHRDIKCANILVDTNGVVKLADFGMAKQV----DKLGLLKSFMGSAHWMAPEV 599
Query 1073 LK-EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + ++ + +D+WS G T+ E+ T G++ + + G
Sbjct 600 VNPKRQYNFLADIWSLGCTVLEMATGDAPF---------------GELECHSVLWKVGNG 644
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
E PD E+ + C E RPT + L+
Sbjct 645 EGPLIPDDLEDEMKDFISKCLEVTVGNRPTCDMLLT 680
Score = 189 bits (481), Expect = 1e-48, Method: Composition-based stats.
Identities = 53/284 (19%), Positives = 101/284 (36%), Gaps = 36/284 (13%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
T + R + +G GT +VYEG +E + +
Sbjct 414 STGRSPGVVSKRPPWDTWFKGDFIGSGTFGSVYEGIDNNGMFFAVKEVSL---------K 464
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
D+G+ + +K L+ +L+S + H ++ G + + E V
Sbjct 465 DQGKVGQEAIKQLEH-----------EIALLSDIQHPNIVQYLGTERDDEKLYIFLELVS 513
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G L ++ + +Q+ S L YL ++ ++H ++ NIL+ T
Sbjct 514 KGSLASL--YKKYYFVYDQVRAYTKQILSGLKYLHDRKIIHRDIKCANILVD-------T 564
Query 752 SPFIKLSDPGVGLGALS---REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ +KL+D G+ + + W+APE + + D W G T+LE+
Sbjct 565 NGVVKLADFGMAKQVDKLGLLKSFMGSAHWMAPEVV-NPKRQYNFLADIWSLGCTVLEMA 623
Query 809 FDGEAPLQSRSPSEKEHFYQR--QHRLPEPSCPQLATLTSQCLT 850
G+AP +P+ ++ S+CL
Sbjct 624 -TGDAPFGELECHSVLWKVGNGEGPLIPDDLEDEMKDFISKCLE 666
>sp|C0LGX1|Y5524_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At5g65240 OS=Arabidopsis thaliana OX=3702
GN=At5g65240 PE=2 SV=1
Length=607
Score = 225 bits (574), Expect = 1e-61, Method: Composition-based stats.
Identities = 70/279 (25%), Positives = 115/279 (41%), Gaps = 20/279 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FGKV G VAVK L P +++E++++ H ++++
Sbjct 290 LGQGGFGKVYKGLL-----SDGTKVAVKRLTDFERPGGDEAFQREVEMISVAVHRNLLRL 344
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ 1017
G C Q E+ LV ++ S+ L + + A G+ YLH
Sbjct 345 IGFCTTQTER--LLVYPFMQNLSVAYCLREIKPGDPVLDWFRRKQIALGAARGLEYLHEH 402
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRD+ A NVLLD D +GDFGLAK V V + APEC+
Sbjct 403 CNPKIIHRDVKAANVLLDEDFEAVVGDFGLAKLV--DVRRTNVTTQVRGTMGHIAPECIS 460
Query 1075 EYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
K +DV+ +G+ L EL+T D S+ + L+ + RL +++++
Sbjct 461 TGKSSEKTDVFGYGIMLLELVTGQRAIDFSRLEEEDDVLLLDHVKKLEREKRLEDIVDKK 520
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ + + C + RP ++ +L+
Sbjct 521 LDEDYIKEEVEMMIQVALLCTQAAPEERPAMSEVVRMLE 559
Score = 191 bits (485), Expect = 6e-50, Method: Composition-based stats.
Identities = 68/364 (19%), Positives = 121/364 (33%), Gaps = 67/364 (18%)
Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + ++ + E ++ + LGQG VY+G L
Sbjct 268 QLRRFAWRELQLATDEFSEKNVLGQGGFGKVYKGLLSDG--------------------- 306
Query 633 RGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+V +K L D AF ++S H +L + G C E ++V +++
Sbjct 307 ----TKVAVKRLTDFERPGGDEAFQREVEMISVAVHRNLLRLIGFCTTQTERLLVYPFMQ 362
Query 692 HGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745
+ + LR + G + W + +A A L YL ++H +V N+LL
Sbjct 363 NLSVAYCLREIKPGDPVLDWFRRKQIALGAARGLEYLHEHCNPKIIHRDVKAANVLLDED 422
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800
A + D G+ R V + +APEC+ G + S D +G+
Sbjct 423 FEAV-------VGDFGLAKLVDVRRTNVTTQVRGTMGHIAPECISTGKS--SEKTDVFGY 473
Query 801 GATLLEICFDGEAPLQSRSPSEK-------EHFYQRQHRLPEPSC------------PQL 841
G LLE+ A SR E +R+ RL + +
Sbjct 474 GIMLLELVTGQRAIDFSRLEEEDDVLLLDHVKKLEREKRLEDIVDKKLDEDYIKEEVEMM 533
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901
+ C P +RP+ ++R L + + + +R+
Sbjct 534 IQVALLCTQAAPEERPAMSEVVRMLEGEGLAERWEEWQNLEVTRQEEFQRLQRRFDWGED 593
Query 902 DLGE 905
+
Sbjct 594 SINN 597
>sp|Q28948|AAPK2_PIG 5'-AMP-activated protein kinase catalytic
subunit alpha-2 OS=Sus scrofa OX=9823 GN=PRKAA2 PE=2 SV=2
Length=552
Score = 224 bits (571), Expect = 1e-61, Method: Composition-based stats.
Identities = 77/274 (28%), Positives = 106/274 (39%), Gaps = 30/274 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953
+ LG G FGKV + + TG VAVK L K+EI L+
Sbjct 15 HYVLGDTLGVGTFGKVKIGEHQ----LTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012
H HIIK + +VMEYV G L DY+ +H + + QQI +
Sbjct 71 FRHPHIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE
Sbjct 129 YCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 184
Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + D+WS GV LY LL L RG
Sbjct 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLF----------------KKIRG 228
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P+ V L+ + + + R T +++
Sbjct 229 GVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDI 262
Score = 178 bits (452), Expect = 5e-46, Method: Composition-based stats.
Identities = 58/298 (19%), Positives = 96/298 (32%), Gaps = 39/298 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
Q RV LG GT V G ++ G
Sbjct 4 KQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGH----------------------- 40
Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+V +K+L+ D+ + H H+ ++ V + MV EYV G
Sbjct 41 -KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGG 99
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L ++ + G V + QQ+ SA+ Y +VH ++ N+LL
Sbjct 100 ELFDYICKH-GRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLD-------AQM 151
Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ E + APE + G + +D W G L +
Sbjct 152 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSCGVILYALLCG 210
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
P+ + +PE +ATL L +P +R + + I
Sbjct 211 TLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWF 268
>sp|Q2QY53|CIPKW_ORYSJ CBL-interacting protein kinase 32 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK32 PE=2 SV=2
Length=438
Score = 221 bits (562), Expect = 1e-61, Method: Composition-based stats.
Identities = 68/297 (23%), Positives = 122/297 (41%), Gaps = 35/297 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959
+GEG F KV + TG+ VA+K L + +H+ K+EI ++ + H ++
Sbjct 18 TIGEGTFAKVKF----ARDTETGDPVAIKILDKEKVLKHKMVEQIKREISTMKLIKHPNV 73
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018
++ + + +V+EYV G L D + H + + + QQ+ + Y H++
Sbjct 74 VRIYEVM--GSKTKIYIVLEYVTGGELFDTIVNHGRMREDEARRYFQQLINAVDYCHSRG 131
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N+LLD+ +K+ DFGL+ + + + +P + APE L++ +
Sbjct 132 VYHRDLKPENLLLDSYGNLKVSDFGLSALSQQIKDDGLLHTTCGTPN-YVAPEVLEDQGY 190
Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
A +D+WS GV L+ LL + ++ L + + E P
Sbjct 191 DGAMADLWSCGVILFVLLAGYLPFED---------------SNLMTLYKKISNAE-FTFP 234
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI--PILKT------VHEKYQGQAPSVFSV 1186
L+ + R T ++ K EKY V++V
Sbjct 235 PWTSFPAKRLLTRILDPNPMTRVTIPEILEDEWFKKGYKRPEFDEKYDTTLDDVYAV 291
Score = 171 bits (434), Expect = 9e-45, Method: Composition-based stats.
Identities = 57/332 (17%), Positives = 104/332 (31%), Gaps = 44/332 (13%)
Query 579 LSFHRVDQK--EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
+S +V ++ + +G+GT V RD
Sbjct 1 MSTTKVKRRVGKYELGRTIGEGTFAKV------------------------KFARDTETG 36
Query 637 LRVVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
V +K+LD H + S M + H ++ ++ V + +V EYV G
Sbjct 37 DPVAIKILDKEKVLKHKMVEQIKREISTMKLIKHPNVVRIYEVMGSKTKIYIVLEYVTGG 96
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L + G + QQL +A+ Y ++ + H ++ N+LL G
Sbjct 97 ELFDTIVNH-GRMREDEARRYFQQLINAVDYCHSRGVYHRDLKPENLLLDSYG------- 148
Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+K+SD G+ + + ++APE L D W G L +
Sbjct 149 NLKVSDFGLSALSQQIKDDGLLHTTCGTPNYVAPEVLEDQGYD-GAMADLWSCGVILFVL 207
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
S + + + P + L ++ L P R + IL D
Sbjct 208 LAGYLPFEDSNLMTLYKKISNAEFTFPPWTSFPAKRLLTRILDPNPMTRVTIPEILEDEW 267
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899
+ + + + VF+
Sbjct 268 FKKGYKRPEFDEKYDTTLDDVYAVFNDSEEHH 299
>sp|C0LGD8|Y1755_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g07550 OS=Arabidopsis thaliana OX=3702
GN=At1g07550 PE=1 SV=1
Length=864
Score = 231 bits (588), Expect = 1e-61, Method: Composition-based stats.
Identities = 66/305 (22%), Positives = 121/305 (40%), Gaps = 19/305 (6%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
++ + +K +G+G FG V C E A+K L Q
Sbjct 543 FKSENRRFTYSDVNKMTNNFQVVIGKGGFGVVYQGCL------NNEQAAIKVLSH-SSAQ 595
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----I 995
+K E+++L ++HE ++ G C+D + L L+ E + G+L+++L +
Sbjct 596 GYKEFKTEVELLLRVHHEKLVSLIGYCDD--DNGLALIYELMGKGNLKEHLSGKPGCSVL 653
Query 996 GLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
L A + G+ YLH +HRD+ + N+LL + KI DFGL+++ G+
Sbjct 654 SWPIRLKIALESAIGIEYLHTGCKPKIVHRDVKSTNILLSEEFEAKIADFGLSRSFLIGN 713
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
E + PE K SDV+SFGV L E+++ D + ++
Sbjct 714 EAQPT--VVAGTFGYLDPEYHKTSLLSMKSDVYSFGVVLLEIISGQDVI-DLSRENCNIV 770
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ + +++ +V L +C + RP ++ +L
Sbjct 771 EWTSFILENGDIESIVDPNLHQDYDTSSAWKVVELAMSCVNRTSKERPNMSQVVHVLNEC 830
Query 1173 HEKYQ 1177
E +
Sbjct 831 LETCE 835
Score = 196 bits (499), Expect = 2e-50, Method: Composition-based stats.
Identities = 63/305 (21%), Positives = 98/305 (32%), Gaps = 60/305 (20%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
+G+G VY+G L E + +KVL S
Sbjct 565 VIGKGGFGVVYQGCLNNE--------------------------QAAIKVLSHSSAQGYK 598
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--K 711
F L+ +V H L + G C ++ E + G L L + G ++W +
Sbjct 599 EFKTEVELLLRVHHEKLVSLIGYCDDDNGLALIYELMGKGNLKEHLSGKPGCSVLSWPIR 658
Query 712 MVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL- 767
+ +A + A + YL +VH +V NILL+ A K++D G+ L
Sbjct 659 LKIALESAIGIEYLHTGCKPKIVHRDVKSTNILLSEEFEA-------KIADFGLSRSFLI 711
Query 768 ----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP--- 820
+L PE + LS D + FG LLEI + SR
Sbjct 712 GNEAQPTVVAGTFGYLDPEY--HKTSLLSMKSDVYSFGVVLLEIISGQDVIDLSRENCNI 769
Query 821 SEKEHFYQRQHRLPEPSCPQLA------------TLTSQCLTYEPTQRPSFRTILRDLTR 868
E F + P L L C+ +RP+ ++ L
Sbjct 770 VEWTSFILENGDIESIVDPNLHQDYDTSSAWKVVELAMSCVNRTSKERPNMSQVVHVLNE 829
Query 869 LQPHN 873
Sbjct 830 CLETC 834
>sp|Q9TTK0|CDKL2_RABIT Cyclin-dependent kinase-like 2 OS=Oryctolagus
cuniculus OX=9986 GN=CDKL2 PE=2 SV=1
Length=566
Score = 224 bits (571), Expect = 1e-61, Method: Composition-based stats.
Identities = 75/283 (27%), Positives = 120/283 (42%), Gaps = 27/283 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG +G V N +G +VA+K L++D + +EI +L+ L HE+++
Sbjct 10 VGEGSYGMVM----KCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
C + +K LV E+V L D L + + + + QI G+ + H+ + I
Sbjct 66 LLEVC--KKKKRWYLVFEFVDHTILDDLELFPNGLDDQVVQKYLFQIINGIGFCHSHNII 123
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFY 1079
HRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L K+
Sbjct 124 HRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVKYG 180
Query 1080 YASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
A DVW+ G + E+L DS + +G + L + G RL
Sbjct 181 KAVDVWAIGCLVTEMLMGEPLFPGDSDIDQLYLIMRCLGNLIPRHQELFYKNPVFAGVRL 240
Query 1135 P----------RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P R K V L K C + RP L+
Sbjct 241 PEIKESEPLERRYPKLSEVVIDLAKKCLHVDPDKRPFCAELLH 283
Score = 162 bits (410), Expect = 1e-40, Method: Composition-based stats.
Identities = 59/321 (18%), Positives = 106/321 (33%), Gaps = 72/321 (22%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-L 644
++ L +G+G+ V + R + G V +K L
Sbjct 1 MEKYENLGLVGEGSYGMVMKCRNKDSGR------------------------IVAIKKFL 36
Query 645 DPSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ + L+ Q+ H +L + VC + +V E+V+H LD L
Sbjct 37 ESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDD-LELFP 95
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ Q+ + + + + N++H ++ NIL+++ G+ +KL D G
Sbjct 96 NGLDDQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFA 148
Query 764 LGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ + V + APE L G A+D W G + E+ GE S
Sbjct 149 RTLAAPGEVYTDYVATRWYRAPELLV-GDVKYGKAVDVWAIGCLVTEMLM-GEPLFPGDS 206
Query 820 PSEKEHFYQR--------------------QHRLPEPS------------CPQLATLTSQ 847
++ + R RLPE + L +
Sbjct 207 DIDQLYLIMRCLGNLIPRHQELFYKNPVFAGVRLPEIKESEPLERRYPKLSEVVIDLAKK 266
Query 848 CLTYEPTQRPSFRTILRDLTR 868
CL +P +RP +L
Sbjct 267 CLHVDPDKRPFCAELLHHDFF 287
>sp|Q05512|MARK2_MOUSE Serine/threonine-protein kinase MARK2 OS=Mus
musculus OX=10090 GN=Mark2 PE=1 SV=3
Length=776
Score = 229 bits (584), Expect = 1e-61, Method: Composition-based stats.
Identities = 84/326 (26%), Positives = 128/326 (39%), Gaps = 29/326 (9%)
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
S T PT + + +S S H + ++ +G
Sbjct 1 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMLRGRNSATSADEQPHIGNYRLLKTIG 60
Query 905 EGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963
+G+F KV L + TG+ VAVK + K +E+ I++ L H +I+K
Sbjct 61 KGNFAKVKL----ARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLF 116
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHR 1022
E EK+L LVMEY G + DYL H + + +QI + Y H + +HR
Sbjct 117 EVIE--TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHR 174
Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YA 1081
DL A N+LLD D +KI DFG + G++ + + APE + K
Sbjct 175 DLKAENLLLDADMNIKIADFGFSNEFTFGNKL----DTFCGSPPYAAPELFQGKKIDGPE 230
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
DVWS GV LY L++ + L E + RG + P
Sbjct 231 VDVWSLGVILYTLVSGSLPFD---------------GQNLKELRERVLRG-KYRIPFYMS 274
Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167
+ +L+K S R T E ++
Sbjct 275 TDCENLLKKFLILNPSKRGTLEQIMK 300
Score = 191 bits (484), Expect = 7e-49, Method: Composition-based stats.
Identities = 61/355 (17%), Positives = 114/355 (32%), Gaps = 49/355 (14%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
+P SN++ R + S + + L +G+G V R + G
Sbjct 27 KPSSKSNMLRGRNSATS---------ADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGK 77
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLA 671
V +K++D + + + + +M ++H ++
Sbjct 78 ------------------------EVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIV 113
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
+ V +V EY G + +L G + +Q+ SA+ Y K +V
Sbjct 114 KLFEVIETEKTLYLVMEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYCHQKFIV 172
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGA 788
H ++ N+LL IK++D G + P+ APE L G
Sbjct 173 HRDLKAENLLLD-------ADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPE-LFQGK 224
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQ 847
+D W G L + G P ++ E R +R+P L +
Sbjct 225 KIDGPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 283
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902
L P++R + I++D H ++ P + +
Sbjct 284 FLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYT 338
>sp|Q1DUU8|HOG1_COCIM Mitogen-activated protein kinase HOG1 OS=Coccidioides
immitis (strain RS) OX=246410 GN=HOG1 PE=3 SV=1
Length=364
Score = 218 bits (555), Expect = 1e-61, Method: Composition-based stats.
Identities = 70/305 (23%), Positives = 115/305 (38%), Gaps = 31/305 (10%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADC 936
+ + T ++ +G G FG V + T + VAVK + K
Sbjct 1 MAEFVRAQIFGTTFEITTRYTDLQPVGMGAFGLVC----SARDQLTNQAVAVKKIMKPFS 56
Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996
P +E+ +L+ L HE++I E + V E + L L +
Sbjct 57 TPVLAKRTYRELKLLKHLRHENVISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLE 114
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
+ F QI G+ Y+H+ +HRDL N+L++ + +KI DFGLA+ Y
Sbjct 115 KQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILINENCDLKICDFGLARVQDPQMTGY- 173
Query 1057 VREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLE 1110
S ++ APE + K+ DVWS G E+L+ + + E
Sbjct 174 -----VSTRYYRAPEIMLTWQKYDVEVDVWSAGCIFAEMLSGRPLFPGKDHVNQFSIITE 228
Query 1111 LIGIAQGQM-------TVLRLTELLERGERLPRPDKC----PCEVYHLMKNCWETEASFR 1159
L+G + L+ + L + ER P +K P V L++ + R
Sbjct 229 LLGSPPDDVIKTICSANTLQFVQSLPKRERQPLSEKFKGAEPLAV-DLLERMLVFDPKKR 287
Query 1160 PTFEN 1164
T
Sbjct 288 ITAAE 292
Score = 135 bits (340), Expect = 5e-33, Method: Composition-based stats.
Identities = 37/231 (16%), Positives = 73/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E D + M + RD+ V +K ++ P +A Y
Sbjct 10 FGTTFE---ITTRYTDLQPVGMGAFGLVCSARDQLTNQAVAVKKIMKPFSTPVLAKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARVQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ G + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDVWSAGCIFAEMLS-GRPLFPGKDHVNQFSI 225
>sp|Q9SFB6|M3KE2_ARATH MAP3K epsilon protein kinase 2 OS=Arabidopsis
thaliana OX=3702 GN=MAP3KE2 PE=2 SV=1
Length=1367
Score = 234 bits (597), Expect = 1e-61, Method: Composition-based stats.
Identities = 74/294 (25%), Positives = 133/294 (45%), Gaps = 28/294 (10%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-C 936
+ S + ++G+G +G+V + + G+ VA+K + +
Sbjct 1 MARQMTSSQFHKSKTLDNKYMLGDEIGKGAYGRVYIG----LDLENGDFVAIKQVSLENI 56
Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996
G + + QEID+L+ L H++I+KY G + + L +++EYV GSL + + + G
Sbjct 57 GQEDLNTIMQEIDLLKNLNHKNIVKYLGSL--KTKTHLHIILEYVENGSLANIIKPNKFG 114
Query 997 ---LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ + ++ Q+ EG+ YLH Q IHRD+ N+L + LVK+ DFG+A + E
Sbjct 115 PFPESLVTVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGLVKLADFGVATKLNEAD- 173
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
+W APE ++ ASD+WS G T+ ELLT
Sbjct 174 --FNTHSVVGTPYWMAPEVIELSGVCAASDIWSVGCTIIELLTCVPPYYD---------- 221
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
Q + R+ + + P PD ++ ++ C++ ++ RP + L+
Sbjct 222 -LQPMPALYRIVQ----DDTPPIPDSLSPDITDFLRLCFKKDSRQRPDAKTLLS 270
Score = 201 bits (512), Expect = 3e-51, Method: Composition-based stats.
Identities = 61/305 (20%), Positives = 106/305 (35%), Gaps = 43/305 (14%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
R + SQ + + +G+G VY G G
Sbjct 3 RQMTSSQFHKSKTLDNKYMLGDEIGKGAYGRVYIGLDLENGDF----------------- 45
Query 632 DRGQELRVVLKV--LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
V +K L+ + + L+ ++H ++ G ++ EY
Sbjct 46 -------VAIKQVSLENIGQEDLNTIMQEIDLLKNLNHKNIVKYLGSLKTKTHLHIILEY 98
Query 690 VEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
VE+G L ++ + G P + V Q+ L YL + ++H ++ G NIL + GL
Sbjct 99 VENGSLANIIKPNKFGPFPESLVTVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGL- 157
Query 749 EGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+KL+D GV + V W+APE + + + A D W G T+
Sbjct 158 ------VKLADFGVATKLNEADFNTHSVVGTPYWMAPEVIE--LSGVCAASDIWSVGCTI 209
Query 805 LEICFDGEAPLQSRSPSEKEH--FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
+E+ P P + +P+ P + C + QRP +T+
Sbjct 210 IELLTC-VPPYYDLQPMPALYRIVQDDTPPIPDSLSPDITDFLRLCFKKDSRQRPDAKTL 268
Query 863 LRDLT 867
L
Sbjct 269 LSHPW 273
>sp|Q552C1|Y9957_DICDI Probable serine/threonine-protein kinase
DDB_G0276181 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0276181
PE=3 SV=1
Length=1555
Score = 234 bits (598), Expect = 2e-61, Method: Composition-based stats.
Identities = 64/270 (24%), Positives = 111/270 (41%), Gaps = 37/270 (14%)
Query 926 MVAVKALK--ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
+VAVK L AD P+ + E+ +L H +++KY G C + +VMEYVP
Sbjct 1057 IVAVKKLHPLADPSPEMIQDFYNEVRVLSMFNHPNVVKYVGGCTKIA--NWSIVMEYVPG 1114
Query 984 GSLRDYLPRHSI--GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN-----DRL 1036
G+L D L + +L A I +G+ YLH+ +H D+ + N+L+ +
Sbjct 1115 GNLMDVLANPVLVIPYKLVLRMALDIAKGLHYLHSLGILHLDMKSPNLLVSSLSTSAKVN 1174
Query 1037 VKIGDFGLA------------KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084
+K+ DF + G ++ W APE ++ + DV
Sbjct 1175 IKVADFNTCINRSRITAGFFNRHTGSGDNNKVEKDSKKGTTLWMAPEVIRGAMYSEKCDV 1234
Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144
+SF + ++E++T + + + +G R P P C
Sbjct 1235 YSFAIIMWEMVTRKLPYSHIAF--------------NCEVEDQVLKGLRPPIPMHCNKNY 1280
Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHE 1174
LM+ CW+ + RP F+ +I + + E
Sbjct 1281 TDLMEQCWDDDPENRPYFDTIIHSISKMIE 1310
Score = 216 bits (550), Expect = 1e-55, Method: Composition-based stats.
Identities = 61/330 (18%), Positives = 114/330 (35%), Gaps = 50/330 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGD----------------------PEEGKMDD 623
+KE+ LG G ++Y G + + +D
Sbjct 983 EKEVVLHERLGTGATGDIYRGLISQDNLNRHISNQDSSGSNSSGSGSGHNWLIARNPSND 1042
Query 624 EDPLVPGRDRGQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680
G ++ V +K L P ++ FY ++S +H ++ G C +
Sbjct 1043 IINKDAIIGSGPQIIVAVKKLHPLADPSPEMIQDFYNEVRVLSMFNHPNVVKYVGGCTKI 1102
Query 681 PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNI 740
+V EYV G L L +P + +A +A L YL + ++H ++ N+
Sbjct 1103 ANWSIVMEYVPGGNLMDVLANPVLVIPYKLVLRMALDIAKGLHYLHSLGILHLDMKSPNL 1162
Query 741 LLARLGLAEGTSPFIKLSDPGVGL-------------------GALSREERVERIPWLAP 781
L++ L + + IK++D + + ++ + W+AP
Sbjct 1163 LVSSLSTSAKVN--IKVADFNTCINRSRITAGFFNRHTGSGDNNKVEKDSKKGTTLWMAP 1220
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCP 839
E + G S D + F + E+ E E + R +P
Sbjct 1221 EVIRGAM--YSEKCDVYSFAIIMWEMVTRKLPYSHIAFNCEVEDQVLKGLRPPIPMHCNK 1278
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
L QC +P RP F TI+ ++++
Sbjct 1279 NYTDLMEQCWDDDPENRPYFDTIIHSISKM 1308
>sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase
kinase 2 OS=Homo sapiens OX=9606 GN=MAP3K2 PE=1 SV=2
Length=619
Score = 226 bits (575), Expect = 2e-61, Method: Composition-based stats.
Identities = 76/290 (26%), Positives = 130/290 (45%), Gaps = 24/290 (8%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP--- 938
D + + + LG+G FG+V L + TG +AVK ++ D
Sbjct 341 MDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCY----DVDTGRELAVKQVQFDPDSPET 396
Query 939 -QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IG 996
+ + + EI +L+ L HE I++Y GC D EK+L + MEY+P GS++D L + +
Sbjct 397 SKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALT 456
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
+ +QI EG+ YLH+ +HRD+ N+L D+ VK+GDFG +K +
Sbjct 457 ENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGT 516
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
+ +W +PE + + +D+WS T+ E+LT + PP E +
Sbjct 517 GMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLT-----EKPPWAEFEAMA--- 568
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ ++ + P +K + EA RP+ + L+
Sbjct 569 ------AIFKIATQPTNPKLPPHVSDYTRDFLKRIF-VEAKLRPSADELL 611
Score = 167 bits (422), Expect = 8e-42, Method: Composition-based stats.
Identities = 60/335 (18%), Positives = 102/335 (30%), Gaps = 49/335 (15%)
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQK---EITQLSHLGQGTRTNVYEGRLRVE 611
P + I RG+ TL + +S + LGQG VY
Sbjct 319 PEYDDSRIRRRGSDIDNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVY------- 371
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE---TASLMSQVSHT 668
L D G+EL V DP + + L+ + H
Sbjct 372 ---------------LCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHE 416
Query 669 HLAFVHGVCVRGPE--NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726
+ +G E + EY+ G + L+ G + +Q+ + YL
Sbjct 417 RIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKA-YGALTENVTRKYTRQILEGVHYLH 475
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-------VGLGALSREERVERIPWL 779
+ +VH ++ G NIL ++ +KL D G + L + W+
Sbjct 476 SNMIVHRDIKGANIL-------RDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWM 528
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP 839
+PE + G D W T++E+ E P + + F P
Sbjct 529 SPEVISG--EGYGRKADIWSVACTVVEMLT--EKPPWAEFEAMAAIFKIATQPTNPKLPP 584
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
++ T L + + L + H
Sbjct 585 HVSDYTRDFLKRIFVEAKLRPSADELLRHMFVHYH 619
>sp|Q64303|PAK2_RAT Serine/threonine-protein kinase PAK 2 OS=Rattus
norvegicus OX=10116 GN=Pak2 PE=1 SV=1
Length=524
Score = 223 bits (568), Expect = 2e-61, Method: Composition-based stats.
Identities = 63/275 (23%), Positives = 110/275 (40%), Gaps = 23/275 (8%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
K+ + +G+G G V + T+ G+ VA+K + P+ + EI +++
Sbjct 245 PKKKYTRYEKIGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINEILVMK 299
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
L + +I+ + E L +VMEY+ GSL D + + AQ+ ++ + +
Sbjct 300 ELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALE 357
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+LHA IHRD+ + NVLL + VK+ DFG + R +W APE
Sbjct 358 FLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEV 414
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + D+WS G+ E++ PP + T
Sbjct 415 VTRKAYGPKVDIWSLGIMAIEMV-----EGEPPYLNENPLRALYLIATNGT--------P 461
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L P+K + C E + R + + L+
Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496
Score = 187 bits (475), Expect = 2e-49, Method: Composition-based stats.
Identities = 60/340 (18%), Positives = 115/340 (34%), Gaps = 56/340 (16%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV------------DQKEITQLSHL 595
R P P + + GA++S + ++++ + +K+ T+ +
Sbjct 196 RSVIDPIPAPVGDSNVDSGAKSSDKQKKKAKMTDEEIMEKLRTIVSIGDPKKKYTRYEKI 255
Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655
GQG V+ D V +K ++
Sbjct 256 GQGASGTVF------------------------TATDVALGQEVAIKQINLQKQPKKELI 291
Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715
+M ++ + ++ + G E +V EY+ G L + + A V
Sbjct 292 INEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVV--TETCMDEAQIAAVC 349
Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREE 771
++ AL +L ++H ++ N+LL G +KL+D G R
Sbjct 350 RECLQALEFLHANQVIHRDIKSDNVLL-------GMEGSVKLTDFGFCAQITPEQSKRST 402
Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
V W+APE + A +D W G +E+ +GE P + +P +
Sbjct 403 MVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNG 459
Query 832 RL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
PE P ++CL + +R S + +L+
Sbjct 460 TPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPF 499
>sp|Q29502|PAK2_RABIT Serine/threonine-protein kinase PAK 2 OS=Oryctolagus
cuniculus OX=9986 GN=PAK2 PE=1 SV=1
Length=524
Score = 223 bits (568), Expect = 2e-61, Method: Composition-based stats.
Identities = 63/275 (23%), Positives = 110/275 (40%), Gaps = 23/275 (8%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
K+ + +G+G G V + T+ G+ VA+K + P+ + EI +++
Sbjct 245 PKKKYTRYEKIGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINEILVMK 299
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
L + +I+ + E L +VMEY+ GSL D + + AQ+ ++ + +
Sbjct 300 ELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALE 357
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+LHA IHRD+ + NVLL + VK+ DFG + R +W APE
Sbjct 358 FLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEV 414
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + D+WS G+ E++ PP + T
Sbjct 415 VTRKAYGPKVDIWSLGIMAIEMV-----EGEPPYLNENPLRALYLIATNGT--------P 461
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L P+K + C E + R + + L+
Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496
Score = 187 bits (474), Expect = 3e-49, Method: Composition-based stats.
Identities = 60/340 (18%), Positives = 115/340 (34%), Gaps = 56/340 (16%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV------------DQKEITQLSHL 595
R P P + + GA++S + ++++ + +K+ T+ +
Sbjct 196 RSVIDPIPAPVGDSHVDSGAKSSDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKI 255
Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655
GQG V+ D V +K ++
Sbjct 256 GQGASGTVF------------------------TATDVALGQEVAIKQINLQKQPKKELI 291
Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715
+M ++ + ++ + G E +V EY+ G L + + A V
Sbjct 292 INEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVV--TETCMDEAQIAAVC 349
Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREE 771
++ AL +L ++H ++ N+LL G +KL+D G R
Sbjct 350 RECLQALEFLHANQVIHRDIKSDNVLL-------GMEGSVKLTDFGFCAQITPEQSKRST 402
Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
V W+APE + A +D W G +E+ +GE P + +P +
Sbjct 403 MVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNG 459
Query 832 RL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
PE P ++CL + +R S + +L+
Sbjct 460 TPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPF 499
>sp|Q8CIN4|PAK2_MOUSE Serine/threonine-protein kinase PAK 2 OS=Mus
musculus OX=10090 GN=Pak2 PE=1 SV=1
Length=524
Score = 223 bits (568), Expect = 2e-61, Method: Composition-based stats.
Identities = 63/275 (23%), Positives = 110/275 (40%), Gaps = 23/275 (8%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
K+ + +G+G G V + T+ G+ VA+K + P+ + EI +++
Sbjct 245 PKKKYTRYEKIGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINEILVMK 299
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
L + +I+ + E L +VMEY+ GSL D + + AQ+ ++ + +
Sbjct 300 ELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALE 357
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+LHA IHRD+ + NVLL + VK+ DFG + R +W APE
Sbjct 358 FLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEV 414
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + D+WS G+ E++ PP + T
Sbjct 415 VTRKAYGPKVDIWSLGIMAIEMV-----EGEPPYLNENPLRALYLIATNGT--------P 461
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L P+K + C E + R + + L+
Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496
Score = 187 bits (475), Expect = 2e-49, Method: Composition-based stats.
Identities = 60/340 (18%), Positives = 115/340 (34%), Gaps = 56/340 (16%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV------------DQKEITQLSHL 595
R P P + + GA++S + ++++ + +K+ T+ +
Sbjct 196 RSVIDPIPAPVGDSNVDSGAKSSDKQKKKAKMTDEEIMEKLRTIVSIGDPKKKYTRYEKI 255
Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655
GQG V+ D V +K ++
Sbjct 256 GQGASGTVF------------------------TATDVALGQEVAIKQINLQKQPKKELI 291
Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715
+M ++ + ++ + G E +V EY+ G L + + A V
Sbjct 292 INEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVV--TETCMDEAQIAAVC 349
Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREE 771
++ AL +L ++H ++ N+LL G +KL+D G R
Sbjct 350 RECLQALEFLHANQVIHRDIKSDNVLL-------GMEGSVKLTDFGFCAQITPEQSKRST 402
Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
V W+APE + A +D W G +E+ +GE P + +P +
Sbjct 403 MVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNG 459
Query 832 RL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
PE P ++CL + +R S + +L+
Sbjct 460 TPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPF 499
>sp|Q13177|PAK2_HUMAN Serine/threonine-protein kinase PAK 2 OS=Homo
sapiens OX=9606 GN=PAK2 PE=1 SV=3
Length=524
Score = 223 bits (568), Expect = 2e-61, Method: Composition-based stats.
Identities = 63/275 (23%), Positives = 110/275 (40%), Gaps = 23/275 (8%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
K+ + +G+G G V + T+ G+ VA+K + P+ + EI +++
Sbjct 245 PKKKYTRYEKIGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINEILVMK 299
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
L + +I+ + E L +VMEY+ GSL D + + AQ+ ++ + +
Sbjct 300 ELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALE 357
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+LHA IHRD+ + NVLL + VK+ DFG + R +W APE
Sbjct 358 FLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEV 414
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + D+WS G+ E++ PP + T
Sbjct 415 VTRKAYGPKVDIWSLGIMAIEMV-----EGEPPYLNENPLRALYLIATNGT--------P 461
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L P+K + C E + R + + L+
Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496
Score = 184 bits (466), Expect = 4e-48, Method: Composition-based stats.
Identities = 58/340 (17%), Positives = 113/340 (33%), Gaps = 56/340 (16%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV------------DQKEITQLSHL 595
R P P + + A++ + ++++ + +K+ T+ +
Sbjct 196 RSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKI 255
Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655
GQG V+ D V +K ++
Sbjct 256 GQGASGTVF------------------------TATDVALGQEVAIKQINLQKQPKKELI 291
Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715
+M ++ + ++ + G E +V EY+ G L + + A V
Sbjct 292 INEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVV--TETCMDEAQIAAVC 349
Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREE 771
++ AL +L ++H ++ N+LL G +KL+D G R
Sbjct 350 RECLQALEFLHANQVIHRDIKSDNVLL-------GMEGSVKLTDFGFCAQITPEQSKRST 402
Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
V W+APE + A +D W G +E+ +GE P + +P +
Sbjct 403 MVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNG 459
Query 832 RL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
PE P ++CL + +R S + +L+
Sbjct 460 TPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPF 499
>sp|C0LGH3|Y5614_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g56140 OS=Arabidopsis thaliana OX=3702
GN=At1g56140 PE=2 SV=2
Length=1033
Score = 233 bits (593), Expect = 2e-61, Method: Composition-based stats.
Identities = 76/317 (24%), Positives = 124/317 (39%), Gaps = 18/317 (6%)
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920
I + R + V P + + LGEG FG V
Sbjct 657 IIRKRRKRYTDDEEILSMDVKPYTFTYSELKSATQDFDPSNKLGEGGFGPVYKG-----K 711
Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
G VAVK L Q + + EI + + H +++K GCC + + LV EY
Sbjct 712 LNDGREVAVKLLSVG-SRQGKGQFVAEIVAISAVQHRNLVKLYGCCYEGEHR--LLVYEY 768
Query 981 VPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDND 1034
+P GSL L + + + G+ YLH + +HRD+ A N+LLD+
Sbjct 769 LPNGSLDQALFGEKTLHLDWSTRYEICLGVARGLVYLHEEARLRIVHRDVKASNILLDSK 828
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
+ K+ DFGLAK + + R G + + APE +DV++FGV EL
Sbjct 829 LVPKVSDFGLAKLYDDKKTHISTRVAG--TIGYLAPEYAMRGHLTEKTDVYAFGVVALEL 886
Query 1095 LTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
++ S ++ + L+ A R EL++ + + + C +
Sbjct 887 VSGRPNSDENLEDEKRYLLEWAWNLHEKGREVELIDHQLT-EFNMEEGKRMIGIALLCTQ 945
Query 1154 TEASFRPTFENLIPILK 1170
T + RP ++ +L
Sbjct 946 TSHALRPPMSRVVAMLS 962
Score = 229 bits (583), Expect = 3e-60, Method: Composition-based stats.
Identities = 63/276 (23%), Positives = 102/276 (37%), Gaps = 47/276 (17%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
P T S+L + ++ + LG+G VY+G+L
Sbjct 676 VKPYTFTYSEL---KSATQDFDPSNKLGEGGFGPVYKGKLNDGR---------------- 716
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
V +K+L F +S V H +L ++G C G ++V E
Sbjct 717 ---------EVAVKLLSVGSRQGKGQFVAEIVAISAVQHRNLVKLYGCCYEGEHRLLVYE 767
Query 689 YVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744
Y+ +G LD L E+ H+ + + + +A L YL + +VH +V NILL
Sbjct 768 YLPNGSLDQALFGEKTLHLDWSTRYEICLGVARGLVYLHEEARLRIVHRDVKASNILLDS 827
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWG 799
+ K+SD G+ ++ + I +LAPE G L+ D +
Sbjct 828 KLVP-------KVSDFGLAKLYDDKKTHISTRVAGTIGYLAPEYAMRG--HLTEKTDVYA 878
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
FG LE+ G EK + + L E
Sbjct 879 FGVVALELVS-GRPNSDENLEDEKRYLLEWAWNLHE 913
>sp|Q875L0|HOG1_CRYPA Mitogen-activated protein kinase HOG1 OS=Cryphonectria
parasitica OX=5116 GN=HOG1 PE=1 SV=1
Length=358
Score = 218 bits (554), Expect = 2e-61, Method: Composition-based stats.
Identities = 66/283 (23%), Positives = 110/283 (39%), Gaps = 29/283 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VA+K + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SARDQLTNQNVAIKKIMKPFSTPVLAKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L + ER P + + L++ + R T + +
Sbjct 252 SLPKRERQPLASKFKNADEQAVDLLERMLVFDPKKRITASDAL 294
Score = 132 bits (331), Expect = 7e-32, Method: Composition-based stats.
Identities = 37/231 (16%), Positives = 75/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E D + M + RD+ V +K ++ P +A Y
Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAIKKIMKPFSTPVLAKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|H2KZW3|M3K20_CAEEL Mitogen-activated protein kinase kinase
kinase zak-1 OS=Caenorhabditis elegans OX=6239 GN=zak-1 PE=2
SV=1
Length=745
Score = 228 bits (582), Expect = 2e-61, Method: Composition-based stats.
Identities = 74/285 (26%), Positives = 121/285 (42%), Gaps = 45/285 (16%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V + DG+ +A+K + ++E +IL + H++II++
Sbjct 37 IGVGTFGAVFSGNWT-LPDGSQRTIALKKVFV---------LEKEAEILSKIRHKNIIQF 86
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----------SIGLAQLLLFAQQICEGMA 1012
G C+ G +V EY GSL D++ ++ +A QI G+
Sbjct 87 YGICKATG-NDFFIVTEYAEKGSLYDFIHSEESQSFASSSGGNSFDVVVKWASQIASGIQ 145
Query 1013 YLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH IHRDL ++NV+LD + + KI DFG +K + + W +
Sbjct 146 YLHYDAVDTIIHRDLKSKNVVLDKNLVCKICDFGTSKDL----THSCTAPSWGGTAAWMS 201
Query 1070 PE-CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE L+ A+DVWS+GV L+E+L+ + + R+ ++
Sbjct 202 PEMILQSEGLTTATDVWSYGVVLWEILSK---------------EVPYKDYSEFRIFTMI 246
Query 1129 ER-GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ G L P CP + LM NCW+ R + L +
Sbjct 247 TQSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQIQGELNRL 291
Score = 199 bits (507), Expect = 6e-52, Method: Composition-based stats.
Identities = 64/321 (20%), Positives = 111/321 (35%), Gaps = 56/321 (17%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
F + + +I H+G GT V+ G + G + +
Sbjct 23 FPDIQRDDIQVGDHIGVGTFGAVFSGNWTLPD---------------------GSQRTIA 61
Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC-VRGPENIMVTEYVEHGPLDVWL 699
LK + + A ++S++ H ++ +G+C G + +VTEY E G L ++
Sbjct 62 LKKV--------FVLEKEAEILSKIRHKNIIQFYGICKATGNDFFIVTEYAEKGSLYDFI 113
Query 700 RRERGHV--------PMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLA 748
E + A Q+AS + YL ++H ++ +N++L +
Sbjct 114 HSEESQSFASSSGGNSFDVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLDK---- 169
Query 749 EGTSPFIKLSDPGVGLGALSREER---VERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ K+ D G W++PE + + L+TA D W +G L
Sbjct 170 ---NLVCKICDFGTSKDLTHSCTAPSWGGTAAWMSPEMILQ-SEGLTTATDVWSYGVVLW 225
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHR---LPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
EI E P + S + +P L L S C P R + R I
Sbjct 226 EILSK-EVPYKDYSEFRIFTMITQSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQI 284
Query 863 LRDLTRLQPHNLADVLTVNPD 883
+L RL +
Sbjct 285 QGELNRLAGNQKVMDECEKFM 305
>sp|Q0JEU6|LERK3_ORYSJ G-type lectin S-receptor-like serine/threonine-protein
kinase LECRK3 OS=Oryza sativa subsp. japonica
OX=39947 GN=LECRK3 PE=3 SV=2
Length=811
Score = 229 bits (585), Expect = 2e-61, Method: Composition-based stats.
Identities = 70/288 (24%), Positives = 117/288 (41%), Gaps = 14/288 (5%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G G V D G +AVK ++ + + + E+ + +H ++++
Sbjct 527 LGTGASGVVYKGQLQ---DEFGTNIAVKKIEK-LQQEAQKEFLVEVQTIGQTFHRNLVRL 582
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH---AQH 1018
G C + E+ LV E++ GSL +L + + + A + G+ YLH +
Sbjct 583 LGFCNEGTER--LLVYEFMSNGSLNTFLFSDTHPHWSLRVQVALGVARGLLYLHEECNKQ 640
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IH D+ +N+LLD++ + KI DFGLAK +P + + APE K
Sbjct 641 IIHCDMKPQNILLDDNFVAKISDFGLAKLLPVNQT--QTNTGIRGTRGYVAPEWFKNIGI 698
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPR 1136
DV+SFGV L EL+ + + + L A R+ L+ +
Sbjct 699 TSKVDVYSFGVILLELVCCRKNVELEVLDEEQTILTYWANDCYKCGRIDLLVAGDDEAIF 758
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
K + C + E S RPT + +L + PS +
Sbjct 759 NIKKVERFVAVALWCLQEEPSMRPTMLKVTQMLDGAVQIPTPPDPSSY 806
Score = 209 bits (533), Expect = 6e-55, Method: Composition-based stats.
Identities = 77/408 (19%), Positives = 140/408 (34%), Gaps = 75/408 (18%)
Query 486 TVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCF 545
TV + S+ ++D + + G F S L L ++ G C
Sbjct 430 TVLIKVPRSTNSPSVFSSGSSKWKEDQKYWILGSSLLFGS-SVLVNFLLISVMLFGTYCS 488
Query 546 SLRR--CCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603
R L QP S L P+ S+L +E+ LG G V
Sbjct 489 ITSRKKTQLSQPSNNSGL--------PPKIFTYSELEKATGGFQEV-----LGTGASGVV 535
Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663
Y+G+L+ E + + +K ++ + F +
Sbjct 536 YKGQLQDEFGTN-----------------------IAVKKIEKLQQEAQKEFLVEVQTIG 572
Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723
Q H +L + G C G E ++V E++ +G L+ +L H + ++ VA +A L
Sbjct 573 QTFHRNLVRLLGFCNEGTERLLVYEFMSNGSLNTFLF-SDTHPHWSLRVQVALGVARGLL 631
Query 724 YLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ER 775
YL NK ++H ++ +NILL + K+SD G+ + +
Sbjct 632 YLHEECNKQIIHCDMKPQNILLD-------DNFVAKISDFGLAKLLPVNQTQTNTGIRGT 684
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
++APE +++ +D + FG LLE+ + E+ + +
Sbjct 685 RGYVAPEWFKNIG--ITSKVDVYSFGVILLELVCCRKNVELEVLDEEQTILTYWANDCYK 742
Query 836 P------------------SCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ + CL EP+ RP+ + +
Sbjct 743 CGRIDLLVAGDDEAIFNIKKVERFVAVALWCLQEEPSMRPTMLKVTQM 790
>sp|P79750|CSF11_TAKRU Macrophage colony-stimulating factor 1
receptor 1 OS=Takifugu rubripes OX=31033 GN=csf1r1 PE=3 SV=1
Length=975
Score = 232 bits (591), Expect = 2e-61, Method: Composition-based stats.
Identities = 92/365 (25%), Positives = 147/365 (40%), Gaps = 88/365 (24%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY--CYDPTNDGTGEMVAVKALKADCGP 938
P ++ F + LK + LG G FGKV + VAVK LKA+
Sbjct 568 PTQLPYNEKWEFPRDKLKLGKVLGAGAFGKVVEATAFGLGEDKDNTLRVAVKMLKANAHS 627
Query 939 QHRSGWKQEIDILRTL-YHEHIIKYKGCCE----------------------DQGEKSLQ 975
R E+ IL L +H++I+ G C + E +
Sbjct 628 DEREALMSELKILSHLGHHQNIVNLLGACTYGGPVLVITEYCSLGDLLNFLRQKAETFVN 687
Query 976 LVM---EYVPLGSLRDYLPRHS-------------------------------------- 994
LVM E + + +
Sbjct 688 LVMNIPEIMENSNDYKNICNQKWYIRSDSGISSTSSSTYLEMRPSQQSHIEASGRKSLCE 747
Query 995 ------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ + LL F+ Q+ +G+ +L +++ IHRD+AARNVLL + R+ KI DFGLA+ +
Sbjct 748 DNGDWPLDIDDLLRFSLQVAQGLDFLASRNCIHRDVAARNVLLTDKRVAKICDFGLARDI 807
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
Y V+ + PV W APE + + + SDVWS+G+ L+E+ + S
Sbjct 808 MNDSNYV-VKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGKS-------- 858
Query 1109 LELIGIAQGQMTVL-RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
M V R ++++RG ++ +PD E+Y +MK CW E + RPTF +
Sbjct 859 ------PYPSMAVDSRFYKMVKRGYQMSQPDFALPEIYMIMKMCWNLEPTERPTFSMISQ 912
Query 1168 ILKTV 1172
++ +
Sbjct 913 MINRL 917
Score = 189 bits (480), Expect = 1e-47, Method: Composition-based stats.
Identities = 66/413 (16%), Positives = 122/413 (30%), Gaps = 107/413 (26%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + ++ LG G V + G D
Sbjct 568 PTQLPYNEKWEFPRDKLKLGKVLGAGAFGKV------------------VEATAFGLGED 609
Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQV-SHTHLAFVHG-------------VC 677
+ LRV +K+L + H D A ++S + H ++ + G C
Sbjct 610 KDNTLRVAVKMLKANAHSDEREALMSELKILSHLGHHQNIVNLLGACTYGGPVLVITEYC 669
Query 678 VRGPENI-----------MVT---EYVEHG------------------------------ 693
G +V E +E+
Sbjct 670 SLGDLLNFLRQKAETFVNLVMNIPEIMENSNDYKNICNQKWYIRSDSGISSTSSSTYLEM 729
Query 694 --PLDVWL----------RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
+ + + + + Q+A L +L ++N +H +V RN+L
Sbjct 730 RPSQQSHIEASGRKSLCEDNGDWPLDIDDLLRFSLQVAQGLDFLASRNCIHRDVAARNVL 789
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAM 795
L K+ D G+ ++ V + + W+APE + +
Sbjct 790 LTDK-------RVAKICDFGLARDIMNDSNYVVKGNARLPVKWMAPESIFDCV--YTVQS 840
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---QHRLPEPSCPQLATLTSQCLTYE 852
D W +G L EI G++P S + + + + Q P+ + P++ + C E
Sbjct 841 DVWSYGILLWEIFSLGKSPYPSMAVDSRFYKMVKRGYQMSQPDFALPEIYMIMKMCWNLE 900
Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
PT+RP+F I + + RL + + K D
Sbjct 901 PTERPTFSMISQMINRLLGGQDEQEKLIYRNVQPEQVAEGEACDEPKRYDPPC 953
>sp|Q9QUK0|CDKL2_MOUSE Cyclin-dependent kinase-like 2 OS=Mus musculus
OX=10090 GN=Cdkl2 PE=2 SV=1
Length=568
Score = 224 bits (570), Expect = 2e-61, Method: Composition-based stats.
Identities = 74/284 (26%), Positives = 122/284 (43%), Gaps = 29/284 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG +G V N +G +VA+K L++D + +EI +L+ L HE+++
Sbjct 10 VGEGSYGMVM----KCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
C + +K LV E+V L D L + + + + QI G+ + H+ + I
Sbjct 66 LLEVC--KKKKRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFCHSHNII 123
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFY 1079
HRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L K+
Sbjct 124 HRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVKYG 180
Query 1080 YASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
A D+W+ G + E+L +S + +G + L + G RL
Sbjct 181 KAVDIWAIGCLVIEMLMGQPLFPGESDIDQLHHIMTCLGNLIPRHQELFYKNPVFAGVRL 240
Query 1135 P------------RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
P R K P V L K C + RP +L+
Sbjct 241 PEVKDAEAEPLESRYPKLPEAVISLAKKCLHIDPDKRPFCADLL 284
Score = 161 bits (408), Expect = 3e-40, Method: Composition-based stats.
Identities = 64/402 (16%), Positives = 124/402 (31%), Gaps = 80/402 (20%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-L 644
++ L +G+G+ V + R + G V +K L
Sbjct 1 MEKYENLGLVGEGSYGMVMKCRNKDSGR------------------------IVAIKKFL 36
Query 645 DPSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ + L+ Q+ H +L + VC + +V E+V+H LD L+
Sbjct 37 ESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDD-LKLFP 95
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ Q+ + + + + N++H ++ NIL+++ G+ +KL D G
Sbjct 96 NGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFA 148
Query 764 LGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ + V + APE L G A+D W G ++E+
Sbjct 149 RTLAAPGEVYTDYVATRWYRAPELLV-GDVKYGKAVDIWAIGCLVIEMLMGQPLFPGESD 207
Query 820 PSEKEHFY-------------------QRQHRLPEPS--------------CPQLATLTS 846
+ H RLPE + +L
Sbjct 208 IDQLHHIMTCLGNLIPRHQELFYKNPVFAGVRLPEVKDAEAEPLESRYPKLPEAVISLAK 267
Query 847 QCLTYEPTQRP-SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
+CL +P +RP + D ++ + + + + +
Sbjct 268 KCLHIDPDKRPFCADLLRHDFFQMDGFAERFSQELQLKIEKDARNNSLPKKSQNRKKEKD 327
Query 906 GHFGK------VSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
G+ V DP + ++ VK K D +
Sbjct 328 DALGEERKTLVVQDTNADPKIKDS-KVFKVKGSKIDVEKMEK 368
>sp|P06782|SNF1_YEAST Carbon catabolite-derepressing protein kinase
OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=SNF1 PE=1 SV=1
Length=633
Score = 226 bits (575), Expect = 2e-61, Method: Composition-based stats.
Identities = 75/279 (27%), Positives = 114/279 (41%), Gaps = 31/279 (11%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG--WKQEIDI 950
H + ++ LGEG FGKV L + TG+ VA+K + + ++EI
Sbjct 51 HIGNYQIVKTLGEGSFGKVKLAY----HTTTGQKVALKIINKKVLAKSDMQGRIEREISY 106
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICE 1009
LR L H HIIK + + E + +V+EY L DY+ R + + F QQI
Sbjct 107 LRLLRHPHIIKLYDVIKSKDE--IIMVIEYAGN-ELFDYIVQRDKMSEQEARRFFQQIIS 163
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ Y H +HRDL N+LLD VKI DFGL+ + +G+ ++ SP + A
Sbjct 164 AVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGN---FLKTSCGSPN-YAA 219
Query 1070 PECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE + + DVWS GV LY +L ++ L + +
Sbjct 220 PEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDE---------------SIPVLFKNI 264
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
G P L+K R + ++
Sbjct 265 SNGV-YTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQ 302
Score = 178 bits (451), Expect = 2e-45, Method: Composition-based stats.
Identities = 54/287 (19%), Positives = 95/287 (33%), Gaps = 40/287 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ LG+G+ V G +V LK+++
Sbjct 54 NYQIVKTLGEGSFGKVKLAYHTTTGQ------------------------KVALKIINKK 89
Query 648 ---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D+ S + + H H+ ++ V E IMV EY + L ++ +R
Sbjct 90 VLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGN-ELFDYI-VQRD 147
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ QQ+ SA+ Y +VH ++ N+LL +K++D G+
Sbjct 148 KMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDE-------HLNVKIADFGLSN 200
Query 765 GALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ + APE + G + +D W G L + P
Sbjct 201 IMTDGNFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYVMLCRRLPFDDESIPV 259
Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
++ + LP+ P A L + L P R S I++D
Sbjct 260 LFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWF 306
>sp|Q9M342|WAKLP_ARATH Wall-associated receptor kinase-like 15
OS=Arabidopsis thaliana OX=3702 GN=WAKL15 PE=2 SV=2
Length=639
Score = 226 bits (575), Expect = 2e-61, Method: Composition-based stats.
Identities = 75/290 (26%), Positives = 129/290 (44%), Gaps = 30/290 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG+V N G VAVK K + E+ IL + H++++K
Sbjct 360 LGFGGFGEVFKG-----NLDDGTTVAVKRAKLG-NEKSIYQIVNEVQILCQVSHKNLVKL 413
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------IGLAQLLLFAQQICEGMAY 1013
GCC + + LV E+VP G+L +++ + L + L+ A Q +G+ Y
Sbjct 414 LGCCIEL--EMPVLVYEFVPNGTLFEHIYGGGGGGGGLYDHLPLRRRLMIAHQTAQGLDY 471
Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
LH+ HRD+ + N+LLD + VK+ DFGL++ + V + + P
Sbjct 472 LHSSSSPPIYHRDVKSSNILLDENLDVKVADFGLSRLGVSDVSH--VTTCAQGTLGYLDP 529
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E ++ SDV+SFGV L+ELLT + + + + L+ + + RL ++++
Sbjct 530 EYYLNFQLTDKSDVYSFGVVLFELLTCKKAIDFNREEEDVNLVVFVRKALKEGRLMDVID 589
Query 1130 RGERLPRPDKCPCEVYH---LMKNCWETEASFRPTF----ENLIPILKTV 1172
+ +K + L + C + RPT + + IL +
Sbjct 590 PVIGIGATEKEIESMKALGVLAELCVKETRQCRPTMQVAAKEIENILHGI 639
Score = 207 bits (526), Expect = 4e-55, Method: Composition-based stats.
Identities = 53/277 (19%), Positives = 97/277 (35%), Gaps = 54/277 (19%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ + LG G V++G L V +K
Sbjct 350 ATDNFAKSNLLGFGGFGEVFKGNLDDG-------------------------TTVAVKRA 384
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER- 703
+ ++ QVSH +L + G C+ ++V E+V +G L +
Sbjct 385 KLGNEKSIYQIVNEVQILCQVSHKNLVKLLGCCIELEMPVLVYEFVPNGTLFEHIYGGGG 444
Query 704 ------GHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPF 754
H+P+ ++++A Q A L YL + + + H +V NILL +
Sbjct 445 GGGGLYDHLPLRRRLMIAHQTAQGLDYLHSSSSPPIYHRDVKSSNILLDE-------NLD 497
Query 755 IKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
+K++D G+ +S V + +L PE L+ D + FG L E+
Sbjct 498 VKVADFGLSRLGVSDVSHVTTCAQGTLGYLDPEYYLN--FQLTDKSDVYSFGVVLFELLT 555
Query 810 DGEAPLQSRSPSEKEHFYQ-----RQHRLPEPSCPQL 841
+A +R + ++ RL + P +
Sbjct 556 CKKAIDFNREEEDVNLVVFVRKALKEGRLMDVIDPVI 592
>sp|Q3TZA2|CDKL4_MOUSE Cyclin-dependent kinase-like 4 OS=Mus musculus
OX=10090 GN=Cdkl4 PE=2 SV=1
Length=342
Score = 217 bits (552), Expect = 2e-61, Method: Composition-based stats.
Identities = 68/301 (23%), Positives = 125/301 (42%), Gaps = 34/301 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960
+GEG +G V + N +G++VA+K ++++ R +EI +L+ L H +++
Sbjct 9 KIGEGSYGVV----FKCRNKSSGQVVAIKKFVESEDDRVVRKIALREIRMLKQLKHPNLV 64
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQH 1018
+ + + LV EY +L + L R+ G++ + Q + + + H +
Sbjct 65 NLIEVFRRK--RKMHLVFEYCDH-TLLNELERNPNGVSDGVIKSVLWQTLQALNFCHKHN 121
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEYK 1077
IHRD+ N+L+ ++KI DFG A+ + G Y D + ++ APE L + K
Sbjct 122 CIHRDVKPENILITKQGMIKICDFGFARILIPGDAY----TDYVATRWYRAPELLVGDTK 177
Query 1078 FYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + DVW+ G ELLT S + +G + + + RG
Sbjct 178 YGSSVDVWAVGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFRSNQFFRGI 237
Query 1133 RLPRPDKC-----------PCEVYHLMKNCWETEASFRPTFENLIP--ILKTVHEKYQGQ 1179
+P P+ P + MK C + R T L+ ++ E +
Sbjct 238 SIPEPEDMETLEEKFSNVQPVAL-SFMKGCLKMNPDERLTCAQLLDSAYFESFQEDQMKR 296
Query 1180 A 1180
Sbjct 297 K 297
Score = 162 bits (411), Expect = 1e-42, Method: Composition-based stats.
Identities = 52/260 (20%), Positives = 93/260 (36%), Gaps = 41/260 (16%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ +L+ +G+G+ V++ R + G V +K
Sbjct 1 MEKYEKLAKIGEGSYGVVFKCRNKSSGQ------------------------VVAIKKFV 36
Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
S D + ++ Q+ H +L + V R + +V EY +H L L R
Sbjct 37 ESEDDRVVRKIALREIRMLKQLKHPNLVNLIEVFRRKRKMHLVFEYCDH-TLLNELERNP 95
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
V V Q AL++ N +H +V NIL+ + G+ IK+ D G
Sbjct 96 NGVSDGVIKSVLWQTLQALNFCHKHNCIHRDVKPENILITKQGM-------IKICDFGFA 148
Query 764 L---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+ + V + APE L G +++D W G E+ G+ +S
Sbjct 149 RILIPGDAYTDYVATRWYRAPELLV-GDTKYGSSVDVWAVGCVFAELL-TGQPLWPGKSD 206
Query 821 SEKEHFYQR--QHRLPEPSC 838
++ + R +P
Sbjct 207 VDQLYLIIRTLGKLIPRHQS 226
>sp|Q9M020|LRK63_ARATH Lectin-domain containing receptor kinase
VI.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK63 PE=2 SV=1
Length=688
Score = 227 bits (578), Expect = 2e-61, Method: Composition-based stats.
Identities = 68/301 (23%), Positives = 121/301 (40%), Gaps = 22/301 (7%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
+P K+ R +G G FG V + + + +AVK + + Q
Sbjct 344 NHPHRLRYKDLYAATDGFKENRIVGTGGFGTVFRGNL---SSPSSDQIAVKKITPN-SMQ 399
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----- 994
+ EI+ L L H++++ +G C+ + + L L+ +Y+P GSL L
Sbjct 400 GVREFIAEIESLGRLRHKNLVNLQGWCKQKND--LLLIYDYIPNGSLDSLLYSRPRQSGV 457
Query 995 -IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
+ A+ I G+ YLH + IHRD+ NVL+++D ++GDFGLA+
Sbjct 458 VLSWNARFKIAKGIASGLLYLHEEWEKVVIHRDIKPSNVLIEDDMNPRLGDFGLARLYER 517
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
G + + + APE + K ASDV++FGV L E+++ + S
Sbjct 518 GSQSNTT--VVVGTIGYMAPELARNGKSSSASDVFAFGVLLLEIVSGRRPTDS---GTFF 572
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM-KNCWETEASFRPTFENLIPIL 1169
L + ++ D + ++ C + RP+ ++ L
Sbjct 573 LADWVMELHARGEILHAVDPRLGFGY-DGVEARLALVVGLLCCHQRPTSRPSMRTVLRYL 631
Query 1170 K 1170
Sbjct 632 N 632
Score = 210 bits (535), Expect = 8e-56, Method: Composition-based stats.
Identities = 61/306 (20%), Positives = 104/306 (34%), Gaps = 57/306 (19%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ +G G V+ G L S ++ +K +
Sbjct 357 ATDGFKENRIVGTGGFGTVFRGNLSSPSSD-----------------------QIAVKKI 393
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
P+ F + ++ H +L + G C + + +++ +Y+ +G LD L
Sbjct 394 TPNSMQGVREFIAEIESLGRLRHKNLVNLQGWCKQKNDLLLIYDYIPNGSLDSLLYSRPR 453
Query 705 H----VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ + +A+ +AS L YL K ++H ++ N+L+ +L
Sbjct 454 QSGVVLSWNARFKIAKGIASGLLYLHEEWEKVVIHRDIKPSNVLI-------EDDMNPRL 506
Query 758 SDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
D G+ + V I ++APE G + S+A D + FG LLEI
Sbjct 507 GDFGLARLYERGSQSNTTVVVGTIGYMAPELARNGKS--SSASDVFAFGVLLLEIVSGRR 564
Query 813 A---------PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLT----SQCLTYEPTQRPSF 859
+ E + RL A L C PT RPS
Sbjct 565 PTDSGTFFLADWVMELHARGEILHAVDPRLGFGYDGVEARLALVVGLLCCHQRPTSRPSM 624
Query 860 RTILRD 865
RT+LR
Sbjct 625 RTVLRY 630
>sp|O65530|PEK14_ARATH Proline-rich receptor-like protein kinase
PERK14 OS=Arabidopsis thaliana OX=3702 GN=PERK14 PE=2 SV=1
Length=731
Score = 228 bits (580), Expect = 2e-61, Method: Composition-based stats.
Identities = 78/334 (23%), Positives = 131/334 (39%), Gaps = 28/334 (8%)
Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVS 912
P + + +++A +++ + + + LGEG FG V
Sbjct 345 PPPIHAKYISSGGCDTKENNSVAKNISMPSGMFSYEELSKATGGFSEENLLGEGGFGYVH 404
Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972
G VAVK LK Q ++ E+D + ++H+H++ G C + ++
Sbjct 405 KGVLK-----NGTEVAVKQLKIG-SYQGEREFQAEVDTISRVHHKHLVSLVGYCVNGDKR 458
Query 973 SLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAA 1026
LV E+VP +L +L + + L A +G+AYLH IHRD+ A
Sbjct 459 --LLVYEFVPKDTLEFHLHENRGSVLEWEMRLRIAVGAAKGLAYLHEDCSPTIIHRDIKA 516
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYR-VREDGDSPVFWYAPECLKEYKFYYASDVW 1085
N+LLD+ K+ DFGLAK + + + + + APE K SDV+
Sbjct 517 ANILLDSKFEAKVSDFGLAKFFSDTNSSFTHISTRVVGTFGYMAPEYASSGKVTDKSDVY 576
Query 1086 SFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMT--------VLRLTELLERGERLPR 1136
SFGV L EL+T S + L+ A+ +T + LE+ +
Sbjct 577 SFGVVLLELITGRPSIFAKDSSTNQSLVDWARPLLTKAISGESFDFLVDSRLEKNYDTTQ 636
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
++ A RP ++ L+
Sbjct 637 MANMAACAAACIRQ----SAWLRPRMSQVVRALE 666
Score = 223 bits (568), Expect = 9e-60, Method: Composition-based stats.
Identities = 56/288 (19%), Positives = 101/288 (35%), Gaps = 48/288 (17%)
Query 565 RGARASPRTLNLSQLSFHRVDQKE--ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
+ A ++ S+ + + ++ + LG+G V++G L+
Sbjct 363 NNSVAKNISMPSGMFSYEELSKATGGFSEENLLGEGGFGYVHKGVLKNG----------- 411
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
V +K L + F +S+V H HL + G CV G +
Sbjct 412 --------------TEVAVKQLKIGSYQGEREFQAEVDTISRVHHKHLVSLVGYCVNGDK 457
Query 683 NIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKN---LVHGNVCGR 738
++V E+V L+ L RG + ++ +A A L+YL ++H ++
Sbjct 458 RLLVYEFVPKDTLEFHLHENRGSVLEWEMRLRIAVGAAKGLAYLHEDCSPTIIHRDIKAA 517
Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSR--------EERVERIPWLAPECLPGGANS 790
NILL A K+SD G+ V ++APE G
Sbjct 518 NILLDSKFEA-------KVSDFGLAKFFSDTNSSFTHISTRVVGTFGYMAPEYASSG--K 568
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838
++ D + FG LLE+ + S + + + L +
Sbjct 569 VTDKSDVYSFGVVLLELITGRPSIFAKDSSTNQSLVDWARPLLTKAIS 616
>sp|A0A8I3S724|AURKA_CANLF Aurora kinase A OS=Canis lupus familiaris
OX=9615 GN=AURKA PE=1 SV=1
Length=405
Score = 219 bits (557), Expect = 2e-61, Method: Composition-based stats.
Identities = 65/290 (22%), Positives = 115/290 (40%), Gaps = 30/290 (10%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQ 939
+ S + + R LG+G FG V L + ++A+K L KA
Sbjct 118 KQKNEESKKRQWALEDFEIGRPLGKGKFGNVYL----AREKQSKFILAIKVLFKAQLEKA 173
Query 940 HRS-GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGL 997
++E++I L H +I++ G D + L++EY PLG++ L +
Sbjct 174 GVEHQLRREVEIQSHLRHPNILRLYGYFHDAT--RVYLILEYAPLGAVYRELQKLSKFDE 231
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ + ++ + ++Y H++ IHRD+ N+LL + +KI DFG + P
Sbjct 232 QRTATYITELADALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSR----- 286
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
R + + PE ++ D+WS GV YE L ++
Sbjct 287 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA-------------- 332
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
T + + R E PD P L+ + S RPT ++++
Sbjct 333 -STYQETYKRISRVE-FTFPDFVPEGARDLISRLLKHNPSQRPTLKDVLE 380
Score = 187 bits (474), Expect = 3e-50, Method: Composition-based stats.
Identities = 59/327 (18%), Positives = 116/327 (35%), Gaps = 48/327 (15%)
Query 549 RCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRL 608
+ PG S + + L ++ LG+G NVY
Sbjct 101 QPSSSAPGNNSEKELATKQKNEESKKRQWAL-------EDFEIGRPLGKGKFGNVYLA-- 151
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD---IALAFYETASLMSQV 665
R++ + + +KVL + + + + S +
Sbjct 152 ----------------------REKQSKFILAIKVLFKAQLEKAGVEHQLRREVEIQSHL 189
Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL 725
H ++ ++G ++ EY G + L++ +LA ALSY
Sbjct 190 RHPNILRLYGYFHDATRVYLILEYAPLGAVYRELQKL-SKFDEQRTATYITELADALSYC 248
Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--REERVERIPWLAPEC 783
+K ++H ++ N+LL G++ +K++D G + A S R + +L PE
Sbjct 249 HSKRVIHRDIKPENLLL-------GSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 301
Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPSCPQLA 842
+ G + +D W G E G+ P ++ + E + + P+
Sbjct 302 IEGRMH--DEKVDLWSLGVLCYEFLV-GKPPFEASTYQETYKRISRVEFTFPDFVPEGAR 358
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRL 869
L S+ L + P+QRP+ + +L +
Sbjct 359 DLISRLLKHNPSQRPTLKDVLEHPWIM 385
>sp|Q4R7T5|CDKL2_MACFA Cyclin-dependent kinase-like 2 OS=Macaca
fascicularis OX=9541 GN=CDKL2 PE=2 SV=1
Length=570
Score = 224 bits (570), Expect = 2e-61, Method: Composition-based stats.
Identities = 75/283 (27%), Positives = 119/283 (42%), Gaps = 27/283 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG +G V N TG +VA+K L++D + +EI +L+ L HE+++
Sbjct 10 VGEGSYGMVV----KCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
C + +K LV E+V L D L + + + + QI G+ + H+ + I
Sbjct 66 LLEVC--KKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNII 123
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFY 1079
HRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L K+
Sbjct 124 HRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVKYG 180
Query 1080 YASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
A DVW+ G + E+ DS + +G + L + G RL
Sbjct 181 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFYKNPVFAGVRL 240
Query 1135 P----------RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P R K V L K C + RP L+
Sbjct 241 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCSELLH 283
Score = 161 bits (407), Expect = 3e-40, Method: Composition-based stats.
Identities = 56/320 (18%), Positives = 101/320 (32%), Gaps = 70/320 (22%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-L 644
++ L +G+G+ V V R++ V +K L
Sbjct 1 MEKYENLGLVGEGSYGMV------------------------VKCRNKDTGRIVAIKKFL 36
Query 645 DPSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ + L+ Q+ H +L + VC + +V E+V+H LD L
Sbjct 37 ESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDD-LELFP 95
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ Q+ + + + + N++H ++ NIL+++ G+ +KL D G
Sbjct 96 NGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFA 148
Query 764 LGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ + V + APE L G A+D W G + E+
Sbjct 149 RTLAAPGEVYTDYVATRWYRAPELLV-GDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSD 207
Query 820 PSEKEHFYQ-------------------RQHRLPEPS------------CPQLATLTSQC 848
+ H RLPE + L +C
Sbjct 208 IDQLYHIMMCLGNLIPRHQELFYKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKC 267
Query 849 LTYEPTQRPSFRTILRDLTR 868
L +P +RP +L
Sbjct 268 LHIDPDKRPFCSELLHHDFF 287
>sp|A0A509AHB6|CDPK1_PLABA Calcium-dependent protein kinase 1
OS=Plasmodium berghei (strain Anka) OX=5823 GN=CDPK1 PE=1 SV=1
Length=523
Score = 223 bits (567), Expect = 2e-61, Method: Composition-based stats.
Identities = 77/290 (27%), Positives = 116/290 (40%), Gaps = 45/290 (16%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR------------SGW 944
K+R LG G +G+V L + A+K +K + R
Sbjct 57 YFKVRKLGSGAYGEVLLCKEKNGHSEK----AIKVIKKSQFDKGRYSDDNKNIEKFHEEI 112
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLF 1003
EI +L++L H +IIK ED+ K LV E+ G L + + RH
Sbjct 113 YNEISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAANI 170
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVRED 1060
+QI G+ YLH + +HRD+ N+LL+N +KI DFGL+ + Y++R D
Sbjct 171 MKQILSGICYLHKHNIVHRDIKPENILLENKNSLLNIKIVDFGLSSFFSKD---YKLR-D 226
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
++ APE LK K+ DVWS GV +Y LL G
Sbjct 227 RLGTAYYIAPEVLK-KKYNEKCDVWSCGVIMYILLCGYPPF---------------GGQN 270
Query 1121 VLRLTELLERG-ERLPRPD--KCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + +E+G D E L+K + + R T E +
Sbjct 271 DQDIIKKVEKGKYYFDFNDWKNISDEAKELIKLMLTYDYNKRCTAEEALN 320
Score = 183 bits (464), Expect = 6e-48, Method: Composition-based stats.
Identities = 51/289 (18%), Positives = 96/289 (33%), Gaps = 28/289 (10%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ ++ LG G V + + + K+ + GR +
Sbjct 55 ESYFKVRKLGSGAYGEVL--LCKEKNGHSEKAIKVIKKSQFDKGRYSDD---------NK 103
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
+ Y SL+ + H ++ + V +VTE+ E G L + R
Sbjct 104 NIEKFHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQII-NRHKF 162
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--- 763
+ +Q+ S + YL N+VH ++ NILL + + IK+ D G+
Sbjct 163 DECDAANIMKQILSGICYLHKHNIVHRDIKPENILLEN----KNSLLNIKIVDFGLSSFF 218
Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+R+ ++APE L + D W G + I G P ++ +
Sbjct 219 SKDYKLRDRLGTAYYIAPEVL---KKKYNEKCDVWSCGVIMY-ILLCGYPPFGGQNDQDI 274
Query 824 EHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
++ + + L LTY+ +R + L
Sbjct 275 IKKVEKGKYYFDFNDWKNISDEAKELIKLMLTYDYNKRCTAEEALNSRW 323
>sp|Q0D4B2|CIPKL_ORYSJ CBL-interacting protein kinase 21 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK21 PE=2 SV=2
Length=525
Score = 223 bits (567), Expect = 2e-61, Method: Composition-based stats.
Identities = 69/272 (25%), Positives = 112/272 (41%), Gaps = 27/272 (10%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEID 949
+ R LGEGHFGKV L + TG A+K L + K+EI
Sbjct 82 MRMGKYEMGRALGEGHFGKVKL----ARHADTGAAFAIKILDRQRILAMKIDEQIKREIA 137
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQIC 1008
L+ L H ++++ + + + +V+EYV G L D + + + + QQ+
Sbjct 138 TLKLLKHPNVVRLHEVSASKTK--IYMVLEYVNGGELFDKIALKGKLSEKEGRKLFQQLM 195
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+ ++Y H + HRDL NVL+D +K+ DFGL+ + + SP +
Sbjct 196 DAVSYCHEKGVYHRDLKPENVLVDAKGNIKVSDFGLSALPQNQRKDGLLHTTCGSPN-YI 254
Query 1069 APECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE L + + SD+WS GV LY +LT Q TV+ ++
Sbjct 255 APEVLLNRGYDGSLSDIWSCGVILYVMLTGNLPFDD--------------QNTVVLYQKI 300
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
L+ R P +++ + R
Sbjct 301 LKGDAR--IPKWLSPGAQDILRKILDPNPITR 330
Score = 178 bits (451), Expect = 3e-46, Method: Composition-based stats.
Identities = 57/319 (18%), Positives = 98/319 (31%), Gaps = 42/319 (13%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ LG+G V R G+ +K+LD
Sbjct 86 KYEMGRALGEGHFGKVKLARHADTGAAF------------------------AIKILDRQ 121
Query 648 H---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
I + + + H ++ +H V + MV EYV G L + +G
Sbjct 122 RILAMKIDEQIKREIATLKLLKHPNVVRLHEVSASKTKIYMVLEYVNGGELFDKI-ALKG 180
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + QQL A+SY K + H ++ N+L+ G IK+SD G+
Sbjct 181 KLSEKEGRKLFQQLMDAVSYCHEKGVYHRDLKPENVLVDAKG-------NIKVSDFGLSA 233
Query 765 GALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
++ ++APE L + D W G L +
Sbjct 234 LPQNQRKDGLLHTTCGSPNYIAPEVLLNRGYD-GSLSDIWSCGVILYVMLTGNLPFDDQN 292
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ + + R+P+ P + + L P R I Q + A
Sbjct 293 TVVLYQKILKGDARIPKWLSPGAQDILRKILDPNPITRLDITGIRAHEWFRQDYTPAMPF 352
Query 879 TVNPDSPASDPTVFHKRYL 897
+ D+ SD +
Sbjct 353 DDDDDNNISDGNLHMTENQ 371
>sp|Q75Q66|HOG1_COLOR Mitogen-activated protein kinase HOG1 OS=Colletotrichum
orbiculare (strain 104-T / ATCC 96160 / CBS
514.97 / LARS 414 / MAFF 240422) OX=1213857 GN=HOG1 PE=3 SV=1
Length=357
Score = 217 bits (553), Expect = 2e-61, Method: Composition-based stats.
Identities = 66/284 (23%), Positives = 108/284 (38%), Gaps = 29/284 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VAVK + K P +E+ +L+ L HE++
Sbjct 24 QPVGMGAFGLVC----SARDQLTNQNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENV 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L + ER P + L++ + R T +
Sbjct 252 SLPKRERQPLKNKFKNADPSAIDLLERMLVFDPKKRITATEALS 295
Score = 130 bits (327), Expect = 2e-31, Method: Composition-based stats.
Identities = 36/213 (17%), Positives = 70/213 (33%), Gaps = 18/213 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E D + M + RD+ V +K ++ P +A Y
Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAVKKIMKPFSTPVLAKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ APE + +D W G E+
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML 208
>sp|Q7RAH3|CDPK1_PLAYO Calcium-dependent protein kinase 1 OS=Plasmodium
yoelii yoelii OX=73239 GN=CDPK1 PE=3 SV=3
Length=535
Score = 223 bits (567), Expect = 2e-61, Method: Composition-based stats.
Identities = 77/290 (27%), Positives = 116/290 (40%), Gaps = 45/290 (16%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR------------SGW 944
K+R LG G +G+V L + A+K +K + R
Sbjct 57 YFKVRKLGSGAYGEVLLCKEKNGHSEK----AIKVIKKSQFDKGRYNDDNKNIEKFHEEI 112
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLF 1003
EI +L++L H +IIK ED+ K LV E+ G L + + RH
Sbjct 113 YNEISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAANI 170
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVRED 1060
+QI G+ YLH + +HRD+ N+LL+N +KI DFGL+ + Y++R D
Sbjct 171 MKQILSGICYLHKHNIVHRDIKPENILLENKNSLLNIKIVDFGLSSFFSKD---YKLR-D 226
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
++ APE LK K+ DVWS GV +Y LL G
Sbjct 227 RLGTAYYIAPEVLK-KKYNEKCDVWSCGVIMYILLCGYPPF---------------GGQN 270
Query 1121 VLRLTELLERG-ERLPRPD--KCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + +E+G D E L+K + + R T E +
Sbjct 271 DQDIIKKVEKGKYYFDFNDWKNISDEAKELIKLMLTYDYNKRCTAEEALN 320
Score = 183 bits (465), Expect = 6e-48, Method: Composition-based stats.
Identities = 51/289 (18%), Positives = 96/289 (33%), Gaps = 28/289 (10%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ ++ LG G V + + + K+ + GR +
Sbjct 55 ESYFKVRKLGSGAYGEVL--LCKEKNGHSEKAIKVIKKSQFDKGRYNDD---------NK 103
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
+ Y SL+ + H ++ + V +VTE+ E G L + R
Sbjct 104 NIEKFHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQII-NRHKF 162
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--- 763
+ +Q+ S + YL N+VH ++ NILL + + IK+ D G+
Sbjct 163 DECDAANIMKQILSGICYLHKHNIVHRDIKPENILLEN----KNSLLNIKIVDFGLSSFF 218
Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+R+ ++APE L + D W G + I G P ++ +
Sbjct 219 SKDYKLRDRLGTAYYIAPEVL---KKKYNEKCDVWSCGVIMY-ILLCGYPPFGGQNDQDI 274
Query 824 EHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
++ + + L LTY+ +R + L
Sbjct 275 IKKVEKGKYYFDFNDWKNISDEAKELIKLMLTYDYNKRCTAEEALNSRW 323
>sp|Q9LY03|IRK_ARATH Probable LRR receptor-like serine/threonine-protein
kinase IRK OS=Arabidopsis thaliana OX=3702 GN=IRK
PE=1 SV=1
Length=964
Score = 231 bits (589), Expect = 2e-61, Method: Composition-based stats.
Identities = 69/282 (24%), Positives = 118/282 (42%), Gaps = 14/282 (5%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
K +LG G FG V T G VA+K L + + +++E+ L L H
Sbjct 679 NKDCELGRGGFGAVYR-----TVIRDGYPVAIKKLTVSSLVKSQDEFEREVKKLGKLRHS 733
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMA 1012
+++K +G + L+ E++ GSL L S+ + +A
Sbjct 734 NLVKLEGYYWTTSLQ--LLIYEFLSGGSLYKQLHEAPGGNSSLSWNDRFNIILGTAKCLA 791
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE- 1071
YLH + IH ++ + NVLLD+ K+GD+GLA+ +P + Y + S + + APE
Sbjct 792 YLHQSNIIHYNIKSSNVLLDSSGEPKVGDYGLARLLPM-LDRYVLSSKIQSALGYMAPEF 850
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ K DV+ FGV + E++T + + L + + + R E ++
Sbjct 851 ACRTVKITEKCDVYGFGVLVLEVVTGKKPVEYMEDDVVVLCDMVREALEDGRADECIDPR 910
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ P + V L C S RP + IL+ +
Sbjct 911 LQGKFPVEEAVAVIKLGLICTSQVPSSRPHMGEAVNILRMIR 952
Score = 173 bits (438), Expect = 1e-42, Method: Composition-based stats.
Identities = 55/311 (18%), Positives = 100/311 (32%), Gaps = 61/311 (20%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+ + LG+G VY +R V +K L S
Sbjct 678 LNKDCELGRGGFGAVYRTVIRDGYP-------------------------VAIKKLTVSS 712
Query 649 H-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG--- 704
F + ++ H++L + G +++ E++ G L L G
Sbjct 713 LVKSQDEFEREVKKLGKLRHSNLVKLEGYYWTTSLQLLIYEFLSGGSLYKQLHEAPGGNS 772
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + + A L+YL N++H N+ N+LL G K+ D G+
Sbjct 773 SLSWNDRFNIILGTAKCLAYLHQSNIIHYNIKSSNVLLDSSGEP-------KVGDYGLAR 825
Query 765 GALSREERV------ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + ++APE ++ D +GFG +LE+ G+ P++
Sbjct 826 LLPMLDRYVLSSKIQSALGYMAPE-FACRTVKITEKCDVYGFGVLVLEVV-TGKKPVEYM 883
Query 819 SPSEKEHFYQRQ-----HRLPEPSCPQL------------ATLTSQCLTYEPTQRPSFRT 861
+ R E P+L L C + P+ RP
Sbjct 884 EDDVVVLCDMVREALEDGRADECIDPRLQGKFPVEEAVAVIKLGLICTSQVPSSRPHMGE 943
Query 862 ILRDLTRLQPH 872
+ L ++
Sbjct 944 AVNILRMIRCP 954
>sp|O81291|LRK44_ARATH L-type lectin-domain containing receptor
kinase IV.4 OS=Arabidopsis thaliana OX=3702 GN=LECRK44 PE=3
SV=1
Length=669
Score = 226 bits (576), Expect = 2e-61, Method: Composition-based stats.
Identities = 81/385 (21%), Positives = 140/385 (36%), Gaps = 32/385 (8%)
Query 798 WGFGA----TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEP 853
W FG L + P+ P+ +R + P ++ L
Sbjct 258 WSFGVNGEAQPLALSKLPRLPVWDLKPTRV-------YRFYKNWVPLISLLLI----PFL 306
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
R I++ + + + + K LG G FG V
Sbjct 307 LIIFLVRFIMKRRRKFAEEVEDWETEFGKNRLRFKDLYYATKGFKDKNILGSGGFGSV-- 364
Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
Y T + +AVK + + Q + EI + + H +++ G C + E
Sbjct 365 --YKGIMPKTKKEIAVKRVSNE-SRQGLKEFVAEIVSIGQMSHRNLVPLVGYCRRRDE-- 419
Query 974 LQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAAR 1027
L LV +Y+P GSL YL P ++ Q + + YLH + IHRD+ A
Sbjct 420 LLLVYDYMPNGSLDKYLYNSPEVTLDWKQRFKVINGVASALFYLHEEWEQVVIHRDVKAS 479
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
NVLLD + ++GDFGLA+ G + R + AP+ ++ + +DV++F
Sbjct 480 NVLLDAELNGRLGDFGLAQLCDHGSDPQTTR--VVGTWGYLAPDHIRTGRATTTTDVFAF 537
Query 1088 GVTLYELLTHCDSSQ--SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
GV L E+ + + + + L+ + + + K V
Sbjct 538 GVLLLEVACGRRPIEINNQSGERVVLVDWVFRFWMEANILDAKDPNLGSEYDQKEVEMVL 597
Query 1146 HLMKNCWETEASFRPTFENLIPILK 1170
L C ++ RPT ++ L+
Sbjct 598 KLGLLCSHSDPLARPTMRQVLQYLR 622
Score = 199 bits (507), Expect = 2e-52, Method: Composition-based stats.
Identities = 61/304 (20%), Positives = 103/304 (34%), Gaps = 52/304 (17%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
K + LG G +VY+G + + + +K +
Sbjct 346 ATKGFKDKNILGSGGFGSVYKGIM------------------------PKTKKEIAVKRV 381
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ER 703
F + Q+SH +L + G C R E ++V +Y+ +G LD +L
Sbjct 382 SNESRQGLKEFVAEIVSIGQMSHRNLVPLVGYCRRRDELLLVYDYMPNGSLDKYLYNSPE 441
Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLA-RLGLAEGTSPFIKLSD 759
+ + V +ASAL YL + ++H +V N+LL L G +L D
Sbjct 442 VTLDWKQRFKVINGVASALFYLHEEWEQVVIHRDVKASNVLLDAELNGRLGDFGLAQLCD 501
Query 760 PGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
G V +LAP+ + G + +T D + FG LLE+ +
Sbjct 502 HG---SDPQTTRVVGTWGYLAPDHIRTGRATTTT--DVFAFGVLLLEVACGRRPIEINNQ 556
Query 820 PSEKEHFYQRQHRLP------------------EPSCPQLATLTSQCLTYEPTQRPSFRT 861
E+ R + + L C +P RP+ R
Sbjct 557 SGERVVLVDWVFRFWMEANILDAKDPNLGSEYDQKEVEMVLKLGLLCSHSDPLARPTMRQ 616
Query 862 ILRD 865
+L+
Sbjct 617 VLQY 620
>sp|C0LGV1|RGI2_ARATH LRR receptor-like serine/threonine-protein
kinase RGI2 OS=Arabidopsis thaliana OX=3702 GN=RGI2 PE=1
SV=1
Length=1135
Score = 233 bits (593), Expect = 3e-61, Method: Composition-based stats.
Identities = 74/322 (23%), Positives = 132/322 (41%), Gaps = 32/322 (10%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL----- 932
P + + L + +G+G G V E++AVK L
Sbjct 766 WQFTPFQKLNFTVEHVLKCLVEGNVIGKGCSGIVYKAEMPNR-----EVIAVKKLWPVTV 820
Query 933 ----KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+ R + E+ L ++ H++I+++ GCC ++ + L +Y+ GSL
Sbjct 821 PNLNEKTKSSGVRDSFSAEVKTLGSIRHKNIVRFLGCCWNKNTRLLM--YDYMSNGSLGS 878
Query 989 YLPRHS----IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGD 1041
L S +G +G+AYLH +HRD+ A N+L+ D IGD
Sbjct 879 LLHERSGVCSLGWEVRYKIILGAAQGLAYLHHDCVPPIVHRDIKANNILIGPDFEPYIGD 938
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FGLAK V +G ++ R + APE K SDV+S+GV + E+LT
Sbjct 939 FGLAKLVDDG-DFARSSNTIAGSYGYIAPEYGYSMKITEKSDVYSYGVVVLEVLTGKQPI 997
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH---LMKNCWETEASF 1158
L ++ + +R +++++G + RP+ E+ + C
Sbjct 998 DPTIPDGLHIVDWVK----KIRDIQVIDQGLQ-ARPESEVEEMMQTLGVALLCINPIPED 1052
Query 1159 RPTFENLIPILKTVHEKYQGQA 1180
RPT +++ +L + ++ +
Sbjct 1053 RPTMKDVAAMLSEICQEREESM 1074
Score = 184 bits (468), Expect = 4e-46, Method: Composition-based stats.
Identities = 48/346 (14%), Positives = 106/346 (31%), Gaps = 46/346 (13%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+ + + +G+G VY+ + ++ L
Sbjct 785 LVEGNVIGKGCSGIVYKAEMPNREVIAVKKLWPVTVPNLNE---------------KTKS 829
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ +F + + H ++ G C +++ +Y+ +G L L G +
Sbjct 830 SGVRDSFSAEVKTLGSIRHKNIVRFLGCCWNKNTRLLMYDYMSNGSLGSLLHERSGVCSL 889
Query 709 AW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
W + + A L+YL + +VH ++ NIL+ + D G+
Sbjct 890 GWEVRYKIILGAAQGLAYLHHDCVPPIVHRDIKANNILIGPDFEPY-------IGDFGLA 942
Query 764 L------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
A S ++APE G + ++ D + +G +LE+ G+ P+
Sbjct 943 KLVDDGDFARSSNTIAGSYGYIAPEY--GYSMKITEKSDVYSYGVVVLEVL-TGKQPIDP 999
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
P + H ++ + + Q L P +++ L
Sbjct 1000 TIP-DGLHIVDWVKKIRDI------QVIDQGLQARPESE--VEEMMQTLGVALLCINPIP 1050
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923
+ + ++ + G G + +D T
Sbjct 1051 EDRPTMKDVAAMLSEICQEREESMKVD-GCSGSCNNGRERGKDDST 1095
>sp|Q28GW8|MELK_XENTR Maternal embryonic leucine zipper kinase
OS=Xenopus tropicalis OX=8364 GN=melk PE=2 SV=1
Length=652
Score = 226 bits (575), Expect = 3e-61, Method: Composition-based stats.
Identities = 70/274 (26%), Positives = 122/274 (45%), Gaps = 26/274 (9%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
Y + +G G F KV L ++ TGE VA+K + + K EID ++ L
Sbjct 12 YYELHETIGTGGFAKVKL----ASHLTTGEKVAIKIMDKESLGDDLPRVKTEIDAMKNLS 67
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYL 1014
H+H+ + E + + +V+EY P G L DY+ + + + +F +QI +AY+
Sbjct 68 HQHVCRLYHVIETPNK--IFMVLEYCPGGELFDYIIAKDRLTEDEARVFFRQIVSAVAYI 125
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H+Q Y HRDL N+L+D D+ +K+ DFGL G +Y+ + + APE ++
Sbjct 126 HSQGYAHRDLKPENLLIDEDQNLKLIDFGLCAKPKGGLDYHLM--TCCGSPAYAAPELIQ 183
Query 1075 EYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ +D+WS GV +Y L+ V+ L + + RG +
Sbjct 184 GKAYIGSEADIWSMGVLMYALMCGYLPFDDD---------------NVMVLYKKIMRG-K 227
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P L+ + + R + ++L+
Sbjct 228 YEIPKWLSPGSVLLLSQMLQVDPKKRISVKHLLS 261
Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats.
Identities = 51/319 (16%), Positives = 99/319 (31%), Gaps = 39/319 (12%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH- 648
+G G V G +V +K++D
Sbjct 14 ELHETIGTGGFAKVKLASHLTTGE------------------------KVAIKIMDKESL 49
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
D M +SH H+ ++ V + MV EY G L ++ + +
Sbjct 50 GDDLPRVKTEIDAMKNLSHQHVCRLYHVIETPNKIFMVLEYCPGGELFDYIIA-KDRLTE 108
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA-- 766
V +Q+ SA++Y+ ++ H ++ N+L+ +KL D G+
Sbjct 109 DEARVFFRQIVSAVAYIHSQGYAHRDLKPENLLIDE-------DQNLKLIDFGLCAKPKG 161
Query 767 ---LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ APE + G A + + D W G + +
Sbjct 162 GLDYHLMTCCGSPAYAAPELIQGKAY-IGSEADIWSMGVLMYALMCGYLPFDDDNVMVLY 220
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
+ + ++ +P+ P L SQ L +P +R S + +L +Q ++
Sbjct 221 KKIMRGKYEIPKWLSPGSVLLLSQMLQVDPKKRISVKHLLSHPWLMQGYSCPVEWQSKYP 280
Query 884 SPASDPTVFHKRYLKKIRD 902
D + +
Sbjct 281 LGYVDEDCVTELSVFYKCS 299
>sp|Q6AXJ9|CDKL1_DANRE Cyclin-dependent kinase-like 1 OS=Danio
rerio OX=7955 GN=cdkl1 PE=2 SV=1
Length=350
Score = 216 bits (551), Expect = 3e-61, Method: Composition-based stats.
Identities = 72/306 (24%), Positives = 133/306 (43%), Gaps = 31/306 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILR 952
+KI +GEG +G V + N TG++VA+K ++++ P + +EI +L+
Sbjct 1 MEKYEKISKIGEGSYGVV----FKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEG 1010
L H +++ + + L LV EY L + L R+ + + Q +
Sbjct 57 QLKHPNLVNLMEVFRRK--RKLHLVFEYCDHTVLNE-LDRYPRGVPEHMVKSIIWQTLQA 113
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
+ + H Q+ IHRD+ N+L+ +++K+ DFG A+ + +YY D + ++ AP
Sbjct 114 VNFCHKQNCIHRDVKPENILITKHQVIKLCDFGFARILTGPCDYY---TDCVATRWYRAP 170
Query 1071 ECL-KEYKFYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRL 1124
E L + ++ DVW+ G ELL+ S + +G + +
Sbjct 171 ELLVGDTQYGPPVDVWAVGCVFAELLSGAPLWPGKSDVDQLYLIRKTLGELIPRHQQVFS 230
Query 1125 TELLERGERLPRPDKC-PCEVY---------HLMKNCWETEASFRPTFENLI--PILKTV 1172
T G +P P + P E+ LMK C + + R + E L+ P ++
Sbjct 231 TNQFFSGVCVPEPQEMEPLELKYPNLSYQALSLMKGCLRMDPAERLSCEQLLEQPYFDSL 290
Query 1173 HEKYQG 1178
E+ +
Sbjct 291 REESES 296
Score = 156 bits (394), Expect = 3e-40, Method: Composition-based stats.
Identities = 51/250 (20%), Positives = 91/250 (36%), Gaps = 40/250 (16%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ ++S +G+G+ V++ R + G V +K
Sbjct 1 MEKYEKISKIGEGSYGVVFKCRNKDTGQ------------------------IVAIKKFV 36
Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
S D I ++ Q+ H +L + V R + +V EY +H L+ R R
Sbjct 37 ESEDDPIIKKIALREIRMLKQLKHPNLVNLMEVFRRKRKLHLVFEYCDHTVLNELDRYPR 96
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
G VP + Q A+++ +N +H +V NIL+ + + IKL D G
Sbjct 97 G-VPEHMVKSIIWQTLQAVNFCHKQNCIHRDVKPENILITKHQV-------IKLCDFGFA 148
Query 764 LGAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ V + APE L G +D W G E+ G +S
Sbjct 149 RILTGPCDYYTDCVATRWYRAPELLV-GDTQYGPPVDVWAVGCVFAELLS-GAPLWPGKS 206
Query 820 PSEKEHFYQR 829
++ + ++
Sbjct 207 DVDQLYLIRK 216
>sp|Q69Q47|CIPKO_ORYSJ CBL-interacting protein kinase 24 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK24 PE=1 SV=1
Length=453
Score = 220 bits (560), Expect = 3e-61, Method: Composition-based stats.
Identities = 65/268 (24%), Positives = 110/268 (41%), Gaps = 29/268 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTLYHEHI 959
+G+G F KV + TG VA+K L D HR K+EI I++ + H +I
Sbjct 23 TIGQGTFAKVKF----AVDADTGAAVAMKVLDKDTILNHRMLHQIKREISIMKIVRHPNI 78
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018
++ G+ + +++E + G L D + R + + + QQ+ + + Y H++
Sbjct 79 VRLNEVLA--GKTKIYIILELITGGELFDKIARQGKLRENEARKYFQQLIDAINYCHSKG 136
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N+LLD+ +K+ DFGL+ +G + APE L +
Sbjct 137 VYHRDLKPENLLLDSRGNLKVSDFGLSTLAQKGVGLLHTT---CGTPNYVAPEVLSNNGY 193
Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
A+DVWS GV LY L+ + + + L + + G + P
Sbjct 194 DGSAADVWSCGVILYVLMAGYLPFE---------------EDDLPTLYDKITAG-QFSCP 237
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165
L+ + R T E +
Sbjct 238 YWFSPGATSLIHRILDPNPKTRITIEQI 265
Score = 182 bits (463), Expect = 2e-48, Method: Composition-based stats.
Identities = 60/294 (20%), Positives = 98/294 (33%), Gaps = 42/294 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
RV + E+ +GQGT V D V +
Sbjct 13 KRVGRYEV--GRTIGQGTFAKV------------------------KFAVDADTGAAVAM 46
Query 642 KVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
KVLD +H + S+M V H ++ ++ V + ++ E + G L
Sbjct 47 KVLDKDTILNHRMLHQIKREISIMKIVRHPNIVRLNEVLAGKTKIYIILELITGGELFDK 106
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ R+ G + QQL A++Y +K + H ++ N+LL G +K+S
Sbjct 107 IARQ-GKLRENEARKYFQQLIDAINYCHSKGVYHRDLKPENLLLDSRG-------NLKVS 158
Query 759 DPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
D G+ A ++APE L +A D W G L +
Sbjct 159 DFGLSTLAQKGVGLLHTTCGTPNYVAPEVLSNNGYD-GSAADVWSCGVILYVLMAGYLPF 217
Query 815 LQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ P+ + Q P P +L + L P R + I D
Sbjct 218 EEDDLPTLYDKITAGQFSCPYWFSPGATSLIHRILDPNPKTRITIEQIREDTWF 271
>sp|Q8LIG4|CIPK3_ORYSJ CBL-interacting protein kinase 3 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK3 PE=2 SV=1
Length=445
Score = 219 bits (559), Expect = 3e-61, Method: Composition-based stats.
Identities = 62/269 (23%), Positives = 112/269 (42%), Gaps = 27/269 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHII 960
+G+G F KV N TG+ VA+K L +HR ++EI ++ + H +++
Sbjct 25 IGQGTFAKVRF----AKNMETGDHVAIKILDKAKVQKHRLVEQIRREICTMKLIQHPNVV 80
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ + +V+EYV G L D + + + + QQ+ + Y H++
Sbjct 81 HLHEVM--GSKTRIFIVLEYVMGGELHDIIATSGRLKEDEARKYFQQLINAVDYCHSRGV 138
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
HRDL N+LLD +K+ DFGL+ + + +P + APE +++ +
Sbjct 139 YHRDLKLENLLLDTAGNIKVSDFGLSAISEQVKADGLLHTTCGTPN-YVAPEVIEDKGYD 197
Query 1080 YA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
A +D+WS GV L+ LL + E I +++ G + P
Sbjct 198 GALADLWSCGVILFVLLAGYLPFED------ENIVSLYNKIS----------GAQFTCPS 241
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIP 1167
E L+ + + R T ++
Sbjct 242 WFSAEAKRLIARILDPNPATRITTSQVLQ 270
Score = 169 bits (428), Expect = 8e-44, Method: Composition-based stats.
Identities = 52/312 (17%), Positives = 94/312 (30%), Gaps = 44/312 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ +GQGT V ++ V +K+LD +
Sbjct 18 KYELGRAIGQGTFAKV------------------------RFAKNMETGDHVAIKILDKA 53
Query 648 HHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ M + H ++ +H V +V EYV G L + G
Sbjct 54 KVQKHRLVEQIRREICTMKLIQHPNVVHLHEVMGSKTRIFIVLEYVMGGELHDII-ATSG 112
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ QQL +A+ Y ++ + H ++ N+LL G IK+SD G+
Sbjct 113 RLKEDEARKYFQQLINAVDYCHSRGVYHRDLKLENLLLDTAG-------NIKVSDFGLSA 165
Query 765 GALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ + ++APE + D W G L + G P +
Sbjct 166 ISEQVKADGLLHTTCGTPNYVAPEVIEDKGYD-GALADLWSCGVIL-FVLLAGYLPFEDE 223
Query 819 SPSEKEH-FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
+ + Q P + L ++ L P R + +L+D + +
Sbjct 224 NIVSLYNKISGAQFTCPSWFSAEAKRLIARILDPNPATRITTSQVLQDQWFKKGYESPVF 283
Query 878 LTVNPDSPASDP 889
Sbjct 284 DDKYYPYFHDVY 295
>sp|Q9LZV7|PXC2_ARATH Leucine-rich repeat receptor-like protein
kinase PXC2 OS=Arabidopsis thaliana OX=3702 GN=PXC2 PE=1 SV=1
Length=967
Score = 231 bits (588), Expect = 3e-61, Method: Composition-based stats.
Identities = 70/276 (25%), Positives = 120/276 (43%), Gaps = 11/276 (4%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+LG G FG V T+ G VAVK L + + +++E+ L L H+++++
Sbjct 692 ELGRGGFGVVYK-----TSLQDGRPVAVKKLTVSGLIKSQEEFEREMRKLGKLRHKNVVE 746
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018
KG Q + L+ E+V GSL +L + Q I G+A+LH+ +
Sbjct 747 IKGYYWTQSLQ--LLIHEFVSGGSLYRHLHGDESVCLTWRQRFSIILGIARGLAFLHSSN 804
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE-CLKEYK 1077
H ++ A NVL+D K+ DFGLA+ + + + S + + APE + K
Sbjct 805 ITHYNMKATNVLIDAAGEAKVSDFGLARLLASALDRCVLSGKVQSALGYTAPEFACRTVK 864
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
DV+ FG+ + E++T + + L + + R+ E ++ R P
Sbjct 865 ITDRCDVYGFGILVLEVVTGKRPVEYAEDDVVVLCETVREGLEEGRVEECVDPRLRGNFP 924
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ V L C S RP E ++ IL+ +
Sbjct 925 AEEAIPVIKLGLVCGSQVPSNRPEMEEVVKILELIQ 960
Score = 167 bits (423), Expect = 7e-41, Method: Composition-based stats.
Identities = 58/313 (19%), Positives = 109/313 (35%), Gaps = 60/313 (19%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+ + S LG+G VY+ L+ V +K L S
Sbjct 687 LNKDSELGRGGFGVVYKTSLQDGRP-------------------------VAVKKLTVSG 721
Query 649 H-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-V 706
F + ++ H ++ + G +++ E+V G L L + +
Sbjct 722 LIKSQEEFEREMRKLGKLRHKNVVEIKGYYWTQSLQLLIHEFVSGGSLYRHLHGDESVCL 781
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ + +A L++L + N+ H N+ N+L+ G A K+SD G+
Sbjct 782 TWRQRFSIILGIARGLAFLHSSNITHYNMKATNVLIDAAGEA-------KVSDFGLARLL 834
Query 767 LSREERV-------ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
S +R + + APE ++ D +GFG +LE+ G+ P++
Sbjct 835 ASALDRCVLSGKVQSALGYTAPE-FACRTVKITDRCDVYGFGILVLEVV-TGKRPVEYAE 892
Query 820 PS-----EKEHFYQRQHRLPEPSCPQLA------------TLTSQCLTYEPTQRPSFRTI 862
E + R+ E P+L L C + P+ RP +
Sbjct 893 DDVVVLCETVREGLEEGRVEECVDPRLRGNFPAEEAIPVIKLGLVCGSQVPSNRPEMEEV 952
Query 863 LRDLTRLQPHNLA 875
++ L +Q +
Sbjct 953 VKILELIQCPSHD 965
>sp|Q9M3D7|LRK14_ARATH Putative L-type lectin-domain containing
receptor kinase I.4 OS=Arabidopsis thaliana OX=3702 GN=LECRK14
PE=3 SV=1
Length=667
Score = 226 bits (575), Expect = 3e-61, Method: Composition-based stats.
Identities = 68/276 (25%), Positives = 110/276 (40%), Gaps = 18/276 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FGKV G +AVK L D Q + E+ + + H +++
Sbjct 356 VGKGGFGKVYKGTLPG-----GRHIAVKRLSHDA-EQGMKQFVAEVVTMGNIQHRNLVPL 409
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA--- 1016
G C +GE L LV EY+ GSL YL S Q + + I + YLH+
Sbjct 410 LGYCRRKGE--LLLVSEYMSNGSLDQYLFYNQNPSPSWLQRISILKDIASALNYLHSGAN 467
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRD+ A NV+LD++ ++GDFG+AK + + + + APE ++
Sbjct 468 PAVLHRDIKASNVMLDSEYNGRLGDFGMAKF--QDPQGNLSATAAVGTIGYMAPELIRTG 525
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+DV++FG+ L E+ + P + L+ L E +
Sbjct 526 T-SKETDVYAFGIFLLEVTCGRRPFEPELPVQKKYLVKWVCECWKQASLLETRDPKLGRE 584
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ V L C RP ++ L
Sbjct 585 FLSEEVEMVLKLGLLCTNDVPESRPDMGQVMQYLSQ 620
Score = 218 bits (555), Expect = 1e-58, Method: Composition-based stats.
Identities = 81/422 (19%), Positives = 145/422 (34%), Gaps = 81/422 (19%)
Query 471 YLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELG 530
Y++ WS S + ++ R + P+ +++ + P + L
Sbjct 250 YILGWSFSKSKEFMQSL--DLSKLPQAPIPRNEQAPVPREE-------KKKLHPLLIGLV 300
Query 531 AALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEIT 590
L +L + RR + E+ S S ++
Sbjct 301 ILLVIPVLMVLGGVYWYRRKKYAEVKESWEKEYG--------PHRYSYKSLYK-ATNGFV 351
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ + +G+G VY+G L + +K L
Sbjct 352 KDALVGKGGFGKVYKGTLPGGRH-------------------------IAVKRLSHDAEQ 386
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP-MA 709
F M + H +L + G C R E ++V+EY+ +G LD +L + P
Sbjct 387 GMKQFVAEVVTMGNIQHRNLVPLLGYCRRKGELLLVSEYMSNGSLDQYLFYNQNPSPSWL 446
Query 710 WKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-- 764
++ + + +ASAL+YL + ++H ++ N++L +L D G+
Sbjct 447 QRISILKDIASALNYLHSGANPAVLHRDIKASNVMLDSEYNG-------RLGDFGMAKFQ 499
Query 765 ---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
G LS V I ++APE + G S D + FG LLE+ G P + P
Sbjct 500 DPQGNLSATAAVGTIGYMAPELIRTGT---SKETDVYAFGIFLLEV-TCGRRPFEPELPV 555
Query 822 EKEHF------YQRQHRLPEPSCPQL------------ATLTSQCLTYEPTQRPSFRTIL 863
+K++ +Q L E P+L L C P RP ++
Sbjct 556 QKKYLVKWVCECWKQASLLETRDPKLGREFLSEEVEMVLKLGLLCTNDVPESRPDMGQVM 615
Query 864 RD 865
+
Sbjct 616 QY 617
>sp|Q54MV2|MRKB_DICDI Probable serine/threonine-protein kinase
MARK-B OS=Dictyostelium discoideum OX=44689 GN=mrkB PE=3 SV=1
Length=715
Score = 227 bits (578), Expect = 3e-61, Method: Composition-based stats.
Identities = 70/289 (24%), Positives = 114/289 (39%), Gaps = 23/289 (8%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
N + +G G KV + TN TG+ A+K K
Sbjct 47 YRNKPQQQQHKKGHKMGNYLLGKTIGSGTSSKVKIG----TNILTGKQYAIKITKPK-RI 101
Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGL 997
+ R ++EI IL+ L H++II+ + + L++E V G L DY+ R +
Sbjct 102 KERKEIEREISILKRLKHDNIIQLHDAIYEDDVGRICLILELVSGGELFDYIVARGRLSE 161
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ F +Q+ G+ Y H+ HRDL N+L+D D +KI DFG + + G+ +
Sbjct 162 KEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDGNLKISDFGYSNIIKPGN----L 217
Query 1058 REDGDSPVFWYAPECLKEYKFYY-ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
+ PE L E ++ D+WS GV LY ++T +L
Sbjct 218 LSTFCGSPVYAPPEILLEKRYNGNEVDIWSMGVILYAMVTG------------QLPWTLT 265
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ V + LL + P +V L+ E R T + +
Sbjct 266 DGVQVEGMDRLLRGEFKYPSHVILSDDVKDLINRMIVAEPVERATLDEI 314
Score = 155 bits (391), Expect = 2e-37, Method: Composition-based stats.
Identities = 39/288 (14%), Positives = 91/288 (32%), Gaps = 20/288 (7%)
Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663
++ ++ + + G + + +K+ P S++
Sbjct 56 HKKGHKMGNYLLGKTIGSGTSSKVKIGTNILTGKQYAIKITKPKRIKERKEIEREISILK 115
Query 664 QVSHTHLAFVHGVCVRGP--ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA 721
++ H ++ +H ++ E V G L ++ RG + +Q+
Sbjct 116 RLKHDNIIQLHDAIYEDDVGRICLILELVSGGELFDYI-VARGRLSEKEGRKFFRQMLCG 174
Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPW 778
L Y + + H ++ N+L+ G +K+SD G +
Sbjct 175 LIYCHSNMVCHRDLKLENLLVDEDG-------NLKISDFGYSNIIKPGNLLSTFCGSPVY 227
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-----RQHRL 833
PE L + +D W G L + G+ P + E + ++
Sbjct 228 APPEILLEKRYN-GNEVDIWSMGVILYAMV-TGQLPWTLTDGVQVEGMDRLLRGEFKYPS 285
Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
+ L ++ + EP +R + I + + +++ N
Sbjct 286 HVILSDDVKDLINRMIVAEPVERATLDEIKTHVWVNKGYDMEPDQEYN 333
>sp|A8WYE4|PAR1_CAEBR Serine/threonine-protein kinase par-1 OS=Caenorhabditis
briggsae OX=6238 GN=par-1 PE=3 SV=1
Length=1088
Score = 232 bits (591), Expect = 3e-61, Method: Composition-based stats.
Identities = 74/269 (28%), Positives = 117/269 (43%), Gaps = 29/269 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHII 960
+G+G+F KV L + TG VA+K + P +E+ I++ L H +I+
Sbjct 133 TIGKGNFAKVKL----AKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIV 188
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHY 1019
K E E++L LV+EY G + DYL H + + +QI + YLH+++
Sbjct 189 KLYQVME--TEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNI 246
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRDL A N+LLD D +KI DFG + G++ + + APE K+
Sbjct 247 IHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKL----DTFCGSPPYAAPELFSGKKYD 302
Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
DVWS GV LY L++ + L E + RG + P
Sbjct 303 GPEVDVWSLGVILYTLVSGSLPFD---------------GQNLKELRERVLRG-KYRIPF 346
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ +L+K R + +N++
Sbjct 347 YMSTDCENLLKKFLVINPQRRSSLDNIMK 375
Score = 197 bits (502), Expect = 3e-50, Method: Composition-based stats.
Identities = 58/322 (18%), Positives = 111/322 (34%), Gaps = 50/322 (16%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
+ S + AR + + +++ + L +G+G V + + G
Sbjct 102 ARSSGQSGMSSRSAARRNDQDVHVGKYK----------LLKTIGKGNFAKVKLAKHVITG 151
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHL 670
V +K++D + + + + +M Q+ H ++
Sbjct 152 H------------------------EVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNI 187
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730
++ V +V EY G + +L G + +Q+ SA+ YL +KN+
Sbjct 188 VKLYQVMETEQTLYLVLEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYLHSKNI 246
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG---ALSREERVERIPWLAPECLPGG 787
+H ++ N+LL + IK++D G + P+ APE G
Sbjct 247 IHRDLKAENLLLDQ-------DMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGK 299
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTS 846
+D W G L + G P ++ E R +R+P L
Sbjct 300 KYD-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLK 357
Query 847 QCLTYEPTQRPSFRTILRDLTR 868
+ L P +R S I++D
Sbjct 358 KFLVINPQRRSSLDNIMKDRWM 379
>sp|O01700|DLK1_CAEEL Mitogen-activated protein kinase kinase
kinase dlk-1 OS=Caenorhabditis elegans OX=6239 GN=dlk-1 PE=1
SV=4
Length=928
Score = 230 bits (587), Expect = 4e-61, Method: Composition-based stats.
Identities = 75/277 (27%), Positives = 117/277 (42%), Gaps = 34/277 (12%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ ++ LG G G V + VAVK + + EI
Sbjct 128 WEIPFDAISELEWLGSGSQGAVFRGQLE------NRTVAVKKVNQLK--------ETEIK 173
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQIC 1008
LR L H++II++ G C +VMEY G L L R++I + ++I
Sbjct 174 HLRHLRHQNIIEFLGVCSKS--PCYCIVMEYCSKGQLCTVLKSRNTITRELFAQWVKEIA 231
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+GM YLH IHRDL + N+L+ + +KI DFG + + V W
Sbjct 232 DGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTSHM---QKKMDSTMMSFCGTVSWM 288
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
APE +K+ DV+SFGV L+E+LT ++P ++ I +L
Sbjct 289 APEMIKKQPCNEKVDVYSFGVVLWEMLTR----ETPYANIAQMAIIFGVGTNILS----- 339
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
LP P++ P + L+K C + RP+F ++
Sbjct 340 -----LPMPEEAPKGLVLLIKQCLSQKGRNRPSFSHI 371
Score = 202 bits (515), Expect = 3e-52, Method: Composition-based stats.
Identities = 60/338 (18%), Positives = 109/338 (32%), Gaps = 51/338 (15%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S+ + I++L LG G++ V+ G+L +
Sbjct 123 SEDELWEIPFDAISELEWLGSGSQGAVFRGQL--------------------------EN 156
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K ++ + + H ++ GVC + P +V EY G L
Sbjct 157 RTVAVKKVNQLKE-------TEIKHLRHLRHQNIIEFLGVCSKSPCYCIVMEYCSKGQLC 209
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
L + R + +++A + YL ++H ++ NIL++ IK
Sbjct 210 TVL-KSRNTITRELFAQWVKEIADGMHYLHQNKVIHRDLKSPNILIS-------AEDSIK 261
Query 757 LSDPGVGLGALSREERV----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
+ D G + + + W+APE + + +D + FG L E+ E
Sbjct 262 ICDFGTSHMQKKMDSTMMSFCGTVSWMAPEMIK--KQPCNEKVDVYSFGVVLWEMLTR-E 318
Query 813 APLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
P + + +PE + L L QCL+ + RPSF I +
Sbjct 319 TPYANIAQMAIIFGVGTNILSLPMPEEAPKGLVLLIKQCLSQKGRNRPSFSHIRQHWEIF 378
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
+P + S G
Sbjct 379 KPELFEMTEEEWQLAWDSYREFAKCIQYPSTVTRDHGG 416
>sp|Q39203|SD22_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase SD2-2 OS=Arabidopsis thaliana OX=3702
GN=SD22 PE=1 SV=1
Length=797
Score = 228 bits (582), Expect = 4e-61, Method: Composition-based stats.
Identities = 72/286 (25%), Positives = 121/286 (42%), Gaps = 29/286 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V + T G+ VAVK L+ S ++ E+ + + H ++++
Sbjct 466 KVGHGGFGAV----FKGTLPGSSTFVAVKRLERPGS--GESEFRAEVCTIGNIQHVNLVR 519
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA-- 1016
+G C + + LV +Y+P GSL YL R S + A +G+AYLH
Sbjct 520 LRGFCSENLHR--LLVYDYMPQGSLSSYLSRTSPKLLSWETRFRIALGTAKGIAYLHEGC 577
Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
IH D+ N+LLD+D K+ DFGLAK + G ++ RV + APE +
Sbjct 578 RDCIIHCDIKPENILLDSDYNAKVSDFGLAKLL--GRDFSRVLATMRGTWGYVAPEWISG 635
Query 1076 YKFYYASDVWSFGVTLYELL-----------THCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+DV+SFG+TL EL+ T + P F A ++ +
Sbjct 636 LPITTKADVYSFGMTLLELIGGRRNVIVNSDTLGEKETEPEKWFFPP--WAAREIIQGNV 693
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+++ + + + C + RP ++ +L+
Sbjct 694 DSVVDSRLNGEYNTEEVTRMATVAIWCIQDNEEIRPAMGTVVKMLE 739
Score = 197 bits (502), Expect = 5e-51, Method: Composition-based stats.
Identities = 53/272 (19%), Positives = 91/272 (33%), Gaps = 43/272 (16%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
LNL SF + +G G V++G L
Sbjct 446 LNLKVFSFKELQSATNGFSDKVGHGGFGAVFKGTL------------------------P 481
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
G V +K L F + + H +L + G C ++V +Y+ G
Sbjct 482 GSSTFVAVKRL-ERPGSGESEFRAEVCTIGNIQHVNLVRLRGFCSENLHRLLVYDYMPQG 540
Query 694 PLDVWLRRERGH-VPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAE 749
L +L R + + +A A ++YL ++H ++ NILL
Sbjct 541 SLSSYLSRTSPKLLSWETRFRIALGTAKGIAYLHEGCRDCIIHCDIKPENILLD------ 594
Query 750 GTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+ K+SD G+ RV ++APE + G ++T D + FG TL
Sbjct 595 -SDYNAKVSDFGLAKLLGRDFSRVLATMRGTWGYVAPEWISG--LPITTKADVYSFGMTL 651
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836
LE+ + + ++ + P
Sbjct 652 LELIGGRRNVIVNSDTLGEKETEPEKWFFPPW 683
>sp|A2QRF6|HOG1_ASPNC Mitogen-activated protein kinase hog1 OS=Aspergillus
niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC
A1513) OX=425011 GN=hog1 PE=3 SV=2
Length=365
Score = 217 bits (552), Expect = 4e-61, Method: Composition-based stats.
Identities = 66/283 (23%), Positives = 108/283 (38%), Gaps = 29/283 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + TG+ VAVK + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SARDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
D+WS E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAACIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L + ER P + + L++ + R +
Sbjct 252 SLPKRERQPLASKFKNADPDAVDLLERMLVFDPKKRIRAGEAL 294
Score = 132 bits (331), Expect = 6e-32, Method: Composition-based stats.
Identities = 35/231 (15%), Positives = 73/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + RD+ V +K ++ P ++ Y
Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSARDQLTGQPVAVKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAACIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q75V57|SAPK9_ORYSJ Serine/threonine-protein kinase SAPK9 OS=Oryza
sativa subsp. japonica OX=39947 GN=SAPK9 PE=1 SV=1
Length=361
Score = 217 bits (552), Expect = 4e-61, Method: Composition-based stats.
Identities = 71/284 (25%), Positives = 119/284 (42%), Gaps = 26/284 (9%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
P + + ++++G G+FG L N +G++VAVK + D G + +
Sbjct 11 MEMPIMHDGDRYELVKEIGSGNFGVARLM----RNRASGDLVAVKYI--DRGEKIDENVQ 64
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFA 1004
+EI R+L H +II++K L +VMEY G L + + + F
Sbjct 65 REIINHRSLRHPNIIRFKEVILTPTH--LAIVMEYASGGELFERICSAGRFSEDEARFFF 122
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGD 1062
QQ+ G++Y H+ HRDL N LLD +KI DFG +K + + +
Sbjct 123 QQLISGVSYCHSMQVCHRDLKLENTLLDGSTAPRLKICDFGYSK---SSVLHSQPKSTVG 179
Query 1063 SPVFWYAPECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
+P + APE L + ++ +DVWS GVTLY +L + P +
Sbjct 180 TPA-YIAPEVLLKKEYDGKIADVWSCGVTLYVMLVGAYPFEDPED----------PKNFR 228
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ ++L +P E L+ + + R T +
Sbjct 229 KTIQKILGVQYSIPDYVHISPECRDLITRIFVGNPASRITMPEI 272
Score = 164 bits (415), Expect = 6e-43, Method: Composition-based stats.
Identities = 57/346 (16%), Positives = 102/346 (29%), Gaps = 43/346 (12%)
Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
RA+ L + H D+ E+ +G G
Sbjct 3 RAAAGPLGMEMPIMHDGDRYELV--KEIGSGNFG------------------------VA 36
Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
R+R V +K +D I + H ++ V + +V
Sbjct 37 RLMRNRASGDLVAVKYIDRG-EKIDENVQREIINHRSLRHPNIIRFKEVILTPTHLAIVM 95
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
EY G L + G QQL S +SY + + H ++ N LL
Sbjct 96 EYASGGELFERI-CSAGRFSEDEARFFFQQLISGVSYCHSMQVCHRDLKLENTLLD---- 150
Query 748 AEGTSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
T+P +K+ D G ++ + V ++APE L D W G TL
Sbjct 151 -GSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD-GKIADVWSCGVTL 208
Query 805 LEICFDGEAPLQSRSPSE----KEHFYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPS 858
+ P + Q+ +P+ P+ L ++ P R +
Sbjct 209 YVMLVGAYPFEDPEDPKNFRKTIQKILGVQYSIPDYVHISPECRDLITRIFVGNPASRIT 268
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
I ++ + + +P + + ++ L
Sbjct 269 MPEIKNHPWFMKNIPADLMDDGMVSNQYEEPDQPMQNMNEIMQILA 314
>sp|Q869X3|Y9851_DICDI Probable serine/threonine-protein kinase
DDB_G0275165 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0275165
PE=3 SV=1
Length=921
Score = 230 bits (586), Expect = 4e-61, Method: Composition-based stats.
Identities = 76/278 (27%), Positives = 127/278 (46%), Gaps = 33/278 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR----SGWKQEIDILRTLYHEH 958
+G G FGKV + G +K + +R ++EI L+ L H +
Sbjct 29 IGSGGFGKVYQGVLNGKEIG------IKKITISDNDPNRDILLKFLEREIYTLKMLSHPN 82
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLLFAQQICEGMAYLHA 1016
+IK+ G E E+SL L+ E V G L Y+ SI + A+ I MAYLH
Sbjct 83 VIKFYGIAEK--ERSLFLLTELVSGGDLHWYIKNKSIDITWKLKVKIARDIAASMAYLHE 140
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRDL + N+L+ + ++K+ D GLA+ + + + + W APE L
Sbjct 141 NGVIHRDLKSTNLLVAENWVIKVCDMGLARKMDKSE---KSKMTICGTDDWMAPEVLIGE 197
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
++ + DV+SFG+ L EL+T + +P + +L + ++ +
Sbjct 198 EYDASCDVFSFGMVLIELITRENL--TPRIRNEDLGVDQKFFLSKV-------------- 241
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
P CP E+ L+ C + S RP+ N++ +L+ + E
Sbjct 242 PADCPKELLRLVSECCKVAPSGRPSASNILGLLEYILE 279
Score = 201 bits (511), Expect = 9e-52, Method: Composition-based stats.
Identities = 63/283 (22%), Positives = 116/283 (41%), Gaps = 36/283 (13%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
D+ + LS +G G VY+G L + G ++ + D DP
Sbjct 19 DEIKFDPLSIIGSGGFGKVYQGVLNGKEIG-IKKITISDNDP------------------ 59
Query 645 DPSHHDIALAFYE-TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ DI L F E + +SH ++ +G+ + ++TE V G L +++ +
Sbjct 60 ---NRDILLKFLEREIYTLKMLSHPNVIKFYGIAEKERSLFLLTELVSGGDLHWYIKNKS 116
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ K+ +A+ +A++++YL ++H ++ N+L+A + IK+ D G+
Sbjct 117 IDITWKLKVKIARDIAASMAYLHENGVIHRDLKSTNLLVAE-------NWVIKVCDMGLA 169
Query 764 LGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
E+ I W+APE L G + D + FG L+E+ + R+
Sbjct 170 RKMDKSEKSKMTICGTDDWMAPEVLIG--EEYDASCDVFSFGMVLIELITRENLTPRIRN 227
Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
++P +L L S+C P+ RPS I
Sbjct 228 EDLGVDQKFFLSKVPADCPKELLRLVSECCKVAPSGRPSASNI 270
>sp|Q54TN4|MKCE_DICDI Probable serine/threonine-protein kinase
mkcE OS=Dictyostelium discoideum OX=44689 GN=mkcE PE=3 SV=1
Length=715
Score = 226 bits (577), Expect = 4e-61, Method: Composition-based stats.
Identities = 64/321 (20%), Positives = 126/321 (39%), Gaps = 20/321 (6%)
Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG--EG 906
L+ P +P R+ + + + L +I + +G
Sbjct 377 LSQNPPIQPMRRSDYNRIFIEPGKFYIFPESESFALARLVVEEEDPSKLFRIGENAEVKG 436
Query 907 HFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC 966
FG V Y VA+K + + R+ EI ILR L H +I+ Y
Sbjct 437 AFGTVYQVFY-VNGQYNNVDVALKKMDHKSEKKRRNN-LNEISILRYLKHPNIVTYINSY 494
Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
E E+ + +VMEY+ G++RD + + + ++I + YL + + HRDL +
Sbjct 495 EKNDEE-IWMVMEYMDGGTIRDAISNFTFTEKYVAYITKEILHSLEYLASLNIAHRDLKS 553
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
N+++++ VK+ DFG + + + + + F+ +PE +++ A D+WS
Sbjct 554 SNIMINSKAEVKLIDFGFSIDL----THLKQDINMCGSPFYMSPEQIQDKAHGLAVDIWS 609
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
G+ + E++ K + L G + + + E++
Sbjct 610 LGIVVAEMVRGRVPHHKSKIKAMFLAGTVGVKFSKEKKYSC-----------HWSPELFD 658
Query 1147 LMKNCWETEASFRPTFENLIP 1167
+ C + + + RPT L+
Sbjct 659 FLNVCLQMDPTKRPTPTQLLQ 679
Score = 171 bits (432), Expect = 1e-42, Method: Composition-based stats.
Identities = 49/299 (16%), Positives = 106/299 (35%), Gaps = 48/299 (16%)
Query 584 VDQKEITQLSHLGQ-----GTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638
V++++ ++L +G+ G VY+ + + +
Sbjct 417 VEEEDPSKLFRIGENAEVKGAFGTVYQ---------------------VFYVNGQYNNVD 455
Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDV 697
V LK +D S++ + H ++ + E MV EY++ G +
Sbjct 456 VALKKMDHKSEKKRRNNLNEISILRYLKHPNIVTYINSYEKNDEEIWMVMEYMDGGTIRD 515
Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ + + +++ +L YL + N+ H ++ NI++ +KL
Sbjct 516 AISN--FTFTEKYVAYITKEILHSLEYLASLNIAHRDLKSSNIMINSK-------AEVKL 566
Query 758 SDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
D G + + +++PE + A+ L A+D W G + E+ G P
Sbjct 567 IDFGFSIDLTHLKQDINMCGSPFYMSPEQIQDKAHGL--AVDIWSLGIVVAEMV-RGRVP 623
Query 815 LQSRSPSEKEHF------YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ ++ + P+L + CL +PT+RP+ +L+
Sbjct 624 HHKSKIKAMFLAGTVGVKFSKEKKYSCHWSPELFDFLNVCLQMDPTKRPTPTQLLQHPF 682
>sp|Q9ZQR3|Y2451_ARATH Leucine-rich repeat receptor-like serine/threonine-protein
kinase At2g14510 OS=Arabidopsis thaliana
OX=3702 GN=At2g14510 PE=1 SV=1
Length=868
Score = 229 bits (584), Expect = 4e-61, Method: Composition-based stats.
Identities = 65/323 (20%), Positives = 126/323 (39%), Gaps = 18/323 (6%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
I R ++ + + + LG+G FG V
Sbjct 528 IFIFRRRKSSTRKVIRPSLEMKNRRFKYSEVKEMTNNFEVVLGKGGFGVVYHGFL----- 582
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
E VAVK L ++ +K E+++L ++H +++ G C++ + L L+ E++
Sbjct 583 -NNEQVAVKVLSQSSTQGYKE-FKTEVELLLRVHHVNLVSLVGYCDEGID--LALIYEFM 638
Query 982 PLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDND 1034
G+L+++L + + L A + G+ YLH +HRD+ + N+LL
Sbjct 639 ENGNLKEHLSGKRGGSVLNWSSRLKIAIESALGIEYLHIGCQPPMVHRDVKSTNILLGLR 698
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
K+ DFGL+++ G + + V + + + PE + SDV+SFG+ L E
Sbjct 699 FEAKLADFGLSRSFLVGSQAH-VSTNVAGTLGYLDPEYYLKNWLTEKSDVYSFGIVLLES 757
Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154
+T + K ++ A+ + + +++ + L C
Sbjct 758 ITGQPVIEQSRDKSY-IVEWAKSMLANGDIESIMDPNLHQDYDSSSSWKALELAMLCINP 816
Query 1155 EASFRPTFENLIPILKTVHEKYQ 1177
++ RP + L E Y
Sbjct 817 SSTQRPNMTRVAHELNECLEIYN 839
Score = 209 bits (532), Expect = 2e-54, Method: Composition-based stats.
Identities = 78/340 (23%), Positives = 118/340 (35%), Gaps = 68/340 (20%)
Query 563 IMRGARASPRTLNLSQLSFH--RVDQKEITQLS-----HLGQGTRTNVYEGRLRVEGSGD 615
I R ++S R + L R E+ +++ LG+G VY G L E
Sbjct 530 IFRRRKSSTRKVIRPSLEMKNRRFKYSEVKEMTNNFEVVLGKGGFGVVYHGFLNNE---- 585
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675
+V +KVL S F L+ +V H +L + G
Sbjct 586 ----------------------QVAVKVLSQSSTQGYKEFKTEVELLLRVHHVNLVSLVG 623
Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNL 730
C G + ++ E++E+G L L +RG + W ++ +A + A + YL +
Sbjct 624 YCDEGIDLALIYEFMENGNLKEHLSGKRGGSVLNWSSRLKIAIESALGIEYLHIGCQPPM 683
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPECL 784
VH +V NILL G KL+D G+ A + +L PE
Sbjct 684 VHRDVKSTNILL-------GLRFEAKLADFGLSRSFLVGSQAHVSTNVAGTLGYLDPEYY 736
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS---EKEHFYQRQHRLPEPSCPQL 841
N L+ D + FG LLE QSR S E + P L
Sbjct 737 L--KNWLTEKSDVYSFGIVLLESITGQPVIEQSRDKSYIVEWAKSMLANGDIESIMDPNL 794
Query 842 A------------TLTSQCLTYEPTQRPSFRTILRDLTRL 869
L C+ TQRP+ + +L
Sbjct 795 HQDYDSSSSWKALELAMLCINPSSTQRPNMTRVAHELNEC 834
>sp|Q55BN8|NEK2_DICDI Probable serine/threonine-protein kinase
nek2 OS=Dictyostelium discoideum OX=44689 GN=nek2 PE=1 SV=1
Length=418
Score = 218 bits (556), Expect = 4e-61, Method: Composition-based stats.
Identities = 60/273 (22%), Positives = 112/273 (41%), Gaps = 32/273 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG+G FG VS G ++ K + + + + E++IL+ L H++I++
Sbjct 10 LGKGSFGVVS----KIKRKEDGRVLVWKEICYENMQEKEKQLLVNEVNILQKLKHQNIVR 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHA 1016
Y D+ L ++ME+ G L + + + + QI + +H
Sbjct 66 YYDRIIDKPSSRLYIIMEHCSGGDLSQLIKKCRNERTYMDEEVIWRTLLQILSALQEIHN 125
Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ +HRD+ N+ LD ++ +K+GDFGLAK + E + ++ +PE +
Sbjct 126 RKDGVILHRDIKPGNLFLDENKNIKLGDFGLAKILNESLYAHT----FVGTPYYMSPEQI 181
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
K+ SDVWS G +YE+ T ++ +LT ++ G
Sbjct 182 HGLKYNERSDVWSVGCLIYEMATLSPPFEAT---------------NQAQLTSKIQVGRY 226
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
P P + + ++ + RP L+
Sbjct 227 NPIPSQYSEHLSKVISLMINVDPKSRPNVNELL 259
Score = 155 bits (392), Expect = 2e-39, Method: Composition-based stats.
Identities = 45/289 (16%), Positives = 101/289 (35%), Gaps = 43/289 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ L LG+G+ V + + + +G + E +++ ++L V
Sbjct 1 MDQYEILGALGKGSFGVVSKIKRKEDGRVLVWK-----EICYENMQEKEKQLLV------ 49
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP--ENIMVTEYVEHGPLDVWL---R 700
+++ ++ H ++ + + P ++ E+ G L + R
Sbjct 50 -----------NEVNILQKLKHQNIVRYYDRIIDKPSSRLYIIMEHCSGGDLSQLIKKCR 98
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKL 757
ER ++ Q+ SAL + N+ ++H ++ N+ L + IKL
Sbjct 99 NERTYMDEEVIWRTLLQILSALQEIHNRKDGVILHRDIKPGNLFLDE-------NKNIKL 151
Query 758 SDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
D G+ +L V +++PE + G + D W G + E+
Sbjct 152 GDFGLAKILNESLYAHTFVGTPYYMSPEQIHG--LKYNERSDVWSVGCLIYEMATLSPPF 209
Query 815 LQSRSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
+ ++ +P L+ + S + +P RP+ +
Sbjct 210 EATNQAQLTSKIQVGRYNPIPSQYSEHLSKVISLMINVDPKSRPNVNEL 258
>sp|Q13470|TNK1_HUMAN Non-receptor tyrosine-protein kinase TNK1
OS=Homo sapiens OX=9606 GN=TNK1 PE=1 SV=3
Length=666
Score = 225 bits (574), Expect = 4e-61, Method: Composition-based stats.
Identities = 99/336 (29%), Positives = 147/336 (44%), Gaps = 27/336 (8%)
Query 845 TSQCLTYEPTQRPSFRTI--LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902
+ L P + I +P +D P+ + + + +
Sbjct 62 ALKRLRSGPKSKNWVYKILGGFAPEHKEPTLPSDSPRHLPEPEGGLKCLIPEGAVCRGEL 121
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRS--GWKQEIDILRTLYHEHI 959
LG G FG V + G VAVK+L+ GP + +E+ ++ L H H+
Sbjct 122 LGSGCFGVVHRGLWT-LPSGKSVPVAVKSLRVGPEGPMGTELGDFLREVSVMMNLEHPHV 180
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015
++ G Q LQ+VME PLGSL L P + +A L LF +Q+ MAYL
Sbjct 181 LRLHGLVLGQ---PLQMVMELAPLGSLHARLTAPAPTPPLLVALLCLFLRQLAGAMAYLG 237
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
A+ +HRDLA RN+LL + R +K+ DFGL + + Y + P W APE L+
Sbjct 238 ARGLVHRDLATRNLLLASPRTIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRH 297
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
F ASDVW FGVTL+E+ + + + + + LE RLP
Sbjct 298 GAFSSASDVWMFGVTLWEMFSGGEE--------------PWAGVPPYLILQRLEDRARLP 343
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
RP C +Y L CW + RP+F +L +L+
Sbjct 344 RPPLCSRALYSLALRCWAPHPADRPSFSHLEGLLQE 379
Score = 187 bits (476), Expect = 2e-48, Method: Composition-based stats.
Identities = 76/294 (26%), Positives = 111/294 (38%), Gaps = 46/294 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ + + + LG G V+ G G+ + V +K
Sbjct 111 IPEGAVCRGELLGSGCFGVVHRGLW---------------------TLPSGKSVPVAVKS 149
Query 644 LDPSHHDIAL----AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
L F S+M + H H+ +HG+ + G MV E G L L
Sbjct 150 LRVGPEGPMGTELGDFLREVSVMMNLEHPHVLRLHGLVL-GQPLQMVMELAPLGSLHARL 208
Query 700 RRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
P+ ++ +QLA A++YL + LVH ++ RN+LLA + IK+
Sbjct 209 TAPAPTPPLLVALLCLFLRQLAGAMAYLGARGLVHRDLATRNLLLA-------SPRTIKV 261
Query 758 SDPGV------GLGAL-SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+D G+ G R W APE L GA S+A D W FG TL E+
Sbjct 262 ADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRHGA--FSSASDVWMFGVTLWEMFSG 319
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTI 862
GE P P + + RLP P L +L +C P RPSF +
Sbjct 320 GEEPWAGVPPYLILQRLEDRARLPRPPLCSRALYSLALRCWAPHPADRPSFSHL 373
>sp|Q9XI96|PERK7_ARATH Proline-rich receptor-like protein kinase
PERK7 OS=Arabidopsis thaliana OX=3702 GN=PERK7 PE=2 SV=1
Length=699
Score = 226 bits (576), Expect = 4e-61, Method: Composition-based stats.
Identities = 80/293 (27%), Positives = 124/293 (42%), Gaps = 49/293 (17%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V G+ +AVK+LKA G R ++ E++I+ ++H H++
Sbjct 342 LGQGGFGYVHKGIL-----PNGKEIAVKSLKAGSGQGERE-FQAEVEIISRVHHRHLVSL 395
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLH---A 1016
G C + G + L LV E++P +L +L S + L A +G+AYLH
Sbjct 396 VGYCSNAGGQRL-LVYEFLPNDTLEFHLHGKSGTVMDWPTRLKIALGSAKGLAYLHEDCH 454
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ A N+LLD++ K+ DFGLAK + + + R + APE
Sbjct 455 PKIIHRDIKASNILLDHNFEAKVADFGLAKLSQDNNTHVSTR--VMGTFGYLAPEYASSG 512
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL-P 1135
K SDV+SFGV L EL+T L+ A+ +R+ + E GE + P
Sbjct 513 KLTEKSDVFSFGVMLLELITGRGPVDLSGDMEDSLVDWARPL--CMRVAQDGEYGELVDP 570
Query 1136 RPDKCPCEVYHLMKNCWETEA------------------SFRPTFENLIPILK 1170
+ + E RP ++ L+
Sbjct 571 FLEH-------------QYEPYEMARMVACAAAAVRHSGRRRPKMSQIVRTLE 610
Score = 218 bits (554), Expect = 4e-58, Method: Composition-based stats.
Identities = 54/270 (20%), Positives = 96/270 (36%), Gaps = 47/270 (17%)
Query 574 LNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
N S ++ + + ++ LGQG V++G L
Sbjct 319 FNNSTFTYEELASATQGFSKDRLLGQGGFGYVHKGILPNGK------------------- 359
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYV 690
+ +K L F ++S+V H HL + G C G + ++V E++
Sbjct 360 ------EIAVKSLKAGSGQGEREFQAEVEIISRVHHRHLVSLVGYCSNAGGQRLLVYEFL 413
Query 691 EHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLG 746
+ L+ L + G + ++ +A A L+YL ++H ++ NILL
Sbjct 414 PNDTLEFHLHGKSGTVMDWPTRLKIALGSAKGLAYLHEDCHPKIIHRDIKASNILLDH-- 471
Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFG 801
+ K++D G+ + V +LAPE G L+ D + FG
Sbjct 472 -----NFEAKVADFGLAKLSQDNNTHVSTRVMGTFGYLAPEYASSG--KLTEKSDVFSFG 524
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
LLE+ G P+ E +
Sbjct 525 VMLLELI-TGRGPVDLSGDMEDSLVDWARP 553
>sp|Q2TA06|AURKA_BOVIN Aurora kinase A OS=Bos taurus OX=9913 GN=AURKA
PE=2 SV=1
Length=402
Score = 218 bits (555), Expect = 4e-61, Method: Composition-based stats.
Identities = 70/322 (22%), Positives = 122/322 (38%), Gaps = 32/322 (10%)
Query 851 YEPTQRPSFRTIL--RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
P RP T + +N + + S + + R LG+G F
Sbjct 85 PRPVTRPPSNTQKSKQPQPPAPGNNPEKEVASKQKNEESKKRQWALEDFEIGRPLGKGKF 144
Query 909 GKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRS-GWKQEIDILRTLYHEHIIKYKGCC 966
G V L + ++A+K L KA ++E++I L H +I++ G
Sbjct 145 GNVYL----AREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYF 200
Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
D + L++EY PLG++ L + + + ++ ++Y H++ IHRD+
Sbjct 201 HDAT--RVYLILEYAPLGAVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 258
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
N+LL + +KI DFG + P R + + PE ++ D+W
Sbjct 259 PENLLLGSAGELKIADFGWSVHAPSSR-----RTTLCGTLDYLPPEMIEGRMHDEKVDLW 313
Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
S GV YE L ++ Q T R++ + PD P
Sbjct 314 SLGVLCYEFLVGKPPFEADTY-----------QETYRRISRV-----EFTFPDCVPEGAR 357
Query 1146 HLMKNCWETEASFRPTFENLIP 1167
L+ + S RPT + ++
Sbjct 358 DLISRLLKHNPSQRPTLKEVLE 379
Score = 188 bits (478), Expect = 7e-51, Method: Composition-based stats.
Identities = 60/340 (18%), Positives = 119/340 (35%), Gaps = 48/340 (14%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
++ P PG + + L ++ LG+G NVY
Sbjct 99 KQPQPPAPGNNPEKEVASKQKNEESKKRQWAL-------EDFEIGRPLGKGKFGNVYLA- 150
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD---IALAFYETASLMSQ 664
R++ + + LKVL + + + + S
Sbjct 151 -----------------------REKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSH 187
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
+ H ++ ++G ++ EY G + L++ +LA+ALSY
Sbjct 188 LRHPNILRLYGYFHDATRVYLILEYAPLGAVYRELQKL-SKFDEQRTATYITELANALSY 246
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--REERVERIPWLAPE 782
+K ++H ++ N+LL G++ +K++D G + A S R + +L PE
Sbjct 247 CHSKRVIHRDIKPENLLL-------GSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPE 299
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQL 841
+ G + +D W G E G+ P ++ + E + + P+
Sbjct 300 MIEGRMH--DEKVDLWSLGVLCYEFLV-GKPPFEADTYQETYRRISRVEFTFPDCVPEGA 356
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
L S+ L + P+QRP+ + +L + +
Sbjct 357 RDLISRLLKHNPSQRPTLKEVLEHPWIIANSKPSSCQKKE 396
>sp|Q8GY82|CRK45_ARATH Cysteine-rich receptor-like protein kinase
45 OS=Arabidopsis thaliana OX=3702 GN=CRK45 PE=1 SV=1
Length=351
Score = 216 bits (550), Expect = 4e-61, Method: Composition-based stats.
Identities = 62/275 (23%), Positives = 109/275 (40%), Gaps = 16/275 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V G+ +AVK L R + E+ IL L H+++I
Sbjct 43 VGRGGFGFVYKGRLQ-----NGQEIAVKILSTSSIRTERQ-FHNELIILSKLKHKNLINL 96
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017
G C + + LV E++P SL ++ + I G+ YLH +
Sbjct 97 LGFCTKRDQHG--LVYEFMPNSSLDCFILDPHRAAQLNWEMCRNIIDGIARGLRYLHEES 154
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRD+ N+LLD+D KI F LA+ + +G E V + PE ++
Sbjct 155 GLWVVHRDIKPGNILLDSDLKPKIVGFELARTMQQGENAAETTE-IVGTVGYLDPEYIRS 213
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ SDV++FGVT+ +++ + ++ + + + + + R E
Sbjct 214 GRVSVKSDVYAFGVTILTIISRRKAWSVDGDSLIKYVRRCWNRGEAIDVIHEVMREEERE 273
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
H+ C + A RP + ++
Sbjct 274 YSISEILRYIHIALLCVDENAERRPNIDKVLHWFS 308
Score = 198 bits (504), Expect = 7e-55, Method: Composition-based stats.
Identities = 56/372 (15%), Positives = 113/372 (30%), Gaps = 61/372 (16%)
Query 560 NLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEG 619
+ + R + S ++ + + +G+G VY+GRL+
Sbjct 8 DTVFRRRKKKSTEFISFFEFDLDTIKAATNDFSELVGRGGFGFVYKGRLQNGQ------- 60
Query 620 KMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR 679
+ +K+L S F+ ++S++ H +L + G C +
Sbjct 61 ------------------EIAVKILSTSSIRTERQFHNELIILSKLKHKNLINLLGFCTK 102
Query 680 GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENKN---LVHGN 734
++ +V E++ + LD ++ + W+M + +A L YL ++ +VH +
Sbjct 103 RDQHGLVYEFMPNSSLDCFILDPHRAAQLNWEMCRNIIDGIARGLRYLHEESGLWVVHRD 162
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGA 788
+ NILL K+ + A E V + +L PE + G
Sbjct 163 IKPGNILLDSDLKP-------KIVGFELARTMQQGENAAETTEIVGTVGYLDPEYIRSG- 214
Query 789 NSLSTAMDKWGFGATLLEICFDG--------------EAPLQSRSPSEKEHFYQRQHRLP 834
+S D + FG T+L I + H R+
Sbjct 215 -RVSVKSDVYAFGVTILTIISRRKAWSVDGDSLIKYVRRCWNRGEAIDVIHEVMREEERE 273
Query 835 EPSCPQLA--TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVF 892
L + C+ +RP+ +L + +
Sbjct 274 YSISEILRYIHIALLCVDENAERRPNIDKVLHWFSCFSTPLPDPTFGNRFLVEEETNWPW 333
Query 893 HKRYLKKIRDLG 904
+
Sbjct 334 SPSLSPGHSSVT 345
>sp|Q5QNM6|CIPKD_ORYSJ Putative CBL-interacting protein kinase
13 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK13 PE=3
SV=1
Length=511
Score = 221 bits (564), Expect = 4e-61, Method: Composition-based stats.
Identities = 71/268 (26%), Positives = 118/268 (44%), Gaps = 26/268 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960
LG+G+F KV Y N TGE VA+K ++ + + + K+EI +LR + H HI+
Sbjct 31 LGQGNFAKV----YHARNVATGEEVAIKVMEKEKIFKSGLTAHIKREIAVLRRVRHPHIV 86
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ + + VMEYV G L + R + A + QQ+ +A+ HA+
Sbjct 87 QLYEVMATK--LRIYFVMEYVRGGELFARVARGRLPEADARRYFQQLVSAVAFCHARGVF 144
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ N+L+D+ +K+ DFGL+ AV +G + + APE L +
Sbjct 145 HRDIKPENLLVDDAGDLKVSDFGLS-AVADGMRRDGLFHTFCGTPAYVAPEVLSRRGYDA 203
Query 1081 A-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
A +D+WS GV L+ L+ Q + + + +G+ P
Sbjct 204 AGADLWSCGVVLFVLMAGYLPFQD---------------RNLAGMYRKIHKGD-FRCPKW 247
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
E+ L++ T R T E ++
Sbjct 248 FSPELIRLLRGVLVTNPQRRATAEGIME 275
Score = 179 bits (453), Expect = 1e-46, Method: Composition-based stats.
Identities = 61/290 (21%), Positives = 101/290 (35%), Gaps = 45/290 (16%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
LGQG VY R G V +KV++
Sbjct 25 FEVGKLLGQGNFAKVYHARNVATGE------------------------EVAIKVMEKEK 60
Query 649 ---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ +++ +V H H+ ++ V V EYV G L + R RG
Sbjct 61 IFKSGLTAHIKREIAVLRRVRHPHIVQLYEVMATKLRIYFVMEYVRGGEL--FARVARGR 118
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763
+P A QQL SA+++ + + H ++ N+L+ G +K+SD G+
Sbjct 119 LPEADARRYFQQLVSAVAFCHARGVFHRDIKPENLLVDDAGD-------LKVSDFGLSAV 171
Query 764 LGALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ R+ ++APE L + D W G L + G P Q R+
Sbjct 172 ADGMRRDGLFHTFCGTPAYVAPEVLSRRGYD-AAGADLWSCGVVL-FVLMAGYLPFQDRN 229
Query 820 PSEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ + R P+ P+L L L P +R + I+ +
Sbjct 230 LAGMYRKIHKGDFRCPKWFSPELIRLLRGVLVTNPQRRATAEGIMENEWF 279
>sp|Q2VWQ3|STE20_TALMA Serine/threonine-protein kinase pakA OS=Talaromyces
marneffei OX=37727 GN=pakA PE=3 SV=1
Length=642
Score = 224 bits (572), Expect = 5e-61, Method: Composition-based stats.
Identities = 61/290 (21%), Positives = 119/290 (41%), Gaps = 24/290 (8%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
+ + +G+G G V + T + VA+K + D P+ + EI +++
Sbjct 357 PTKKYYNLNKIGQGASGGV----FTAYETNTNKCVAIKQMNLDLQPK-KDLIINEILVMK 411
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
H++I+ + + L +VMEY+ GSL D + + + Q+ ++ G+
Sbjct 412 DSKHKNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMSEGQIAAVCRETLSGLQ 469
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+LH++ IHRD+ + N+LL D +K+ DFG + ++ R +W APE
Sbjct 470 HLHSKGVIHRDIKSDNILLSMDGEIKLTDFGFCAQI---NDSQNKRNTMVGTPYWMAPEV 526
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ ++ D+WS G+ E++ + + L IA ++ + L
Sbjct 527 VTRKEYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLIATNGTPKIKDEQNLSPVF 585
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI-LKTVHEKYQGQAP 1181
R + HL + R + +L+ ++ E AP
Sbjct 586 R---------DFLHLALR---VDPEKRASAHDLLKHPFMSICEPLNSLAP 623
Score = 180 bits (457), Expect = 4e-46, Method: Composition-based stats.
Identities = 58/332 (17%), Positives = 101/332 (30%), Gaps = 51/332 (15%)
Query 550 CCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLR 609
P+P R + A L + K+ L+ +GQG V+
Sbjct 329 VARPRPR-------TRQSTAFDVRAKLQAICTPGDPTKKYYNLNKIGQGASGGVF----- 376
Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTH 669
+ V +K ++ +M H +
Sbjct 377 -------------------TAYETNTNKCVAIKQMNLDLQPKKDLIINEILVMKDSKHKN 417
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729
+ + G + +V EY+E G L + + V ++ S L +L +K
Sbjct 418 IVNFLDSYLHGLDLWVVMEYMEGGSLTDVV--TFNIMSEGQIAAVCRETLSGLQHLHSKG 475
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLP 785
++H ++ NILL+ IKL+D G R V W+APE +
Sbjct 476 VIHRDIKSDNILLS-------MDGEIKLTDFGFCAQINDSQNKRNTMVGTPYWMAPEVVT 528
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL----PEPSCPQL 841
+D W G +E+ +GE P + SP + + P
Sbjct 529 --RKEYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLIATNGTPKIKDEQNLSPVF 585
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
L +P +R S +L+
Sbjct 586 RDFLHLALRVDPEKRASAHDLLKHPFMSICEP 617
>sp|P53670|LIMK2_RAT LIM domain kinase 2 OS=Rattus norvegicus
OX=10116 GN=Limk2 PE=2 SV=1
Length=638
Score = 224 bits (572), Expect = 5e-61, Method: Composition-based stats.
Identities = 79/309 (26%), Positives = 131/309 (42%), Gaps = 38/309 (12%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
S + +F L LG+G FG+ T+ TG+++ +K L C + +
Sbjct 316 RCSSSYSQQIFRPCDLIHGEVLGKGFFGQ----AIKVTHKATGKVMVMKEL-IRCDEETQ 370
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQL 1000
+ E+ ++R+L H +++K+ G +K L L+ EY+ G+L+D+L Q
Sbjct 371 KTFLTEVKVMRSLDHPNVLKFIGVLYK--DKKLNLLTEYIEGGTLKDFLRNVDPFPWQQK 428
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG--------- 1051
+ FA+ I GMAYLH+ IHRDL + N L+ D+ V + DFGL++ + E
Sbjct 429 VRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRPPVEKA 488
Query 1052 --------HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
+ R +W APE L + DV+SFG+ L E++ +
Sbjct 489 ATKKRTLRKSDRKKRYTVVGNPYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPD 548
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163
+ L+ G L + + P CP + L C + E RP F
Sbjct 549 CLPRTLDF-----GLNVKLFWEKFV--------PTDCPPAFFPLAAICCKLEPESRPAFS 595
Query 1164 NLIPILKTV 1172
L + +
Sbjct 596 KLEDSFEAL 604
Score = 201 bits (512), Expect = 3e-53, Method: Composition-based stats.
Identities = 63/345 (18%), Positives = 112/345 (32%), Gaps = 62/345 (18%)
Query 553 PQPGETSNLIIMRGARASPRTLN-LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
P P +++ + +L S S ++ LG+G + +
Sbjct 294 PGPSSPKEPLLLSRDISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKAT 353
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
G +V+K L + F +M + H ++
Sbjct 354 GK------------------------VMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVL 389
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
GV + + ++TEY+E G L +LR P K+ A+ +AS ++YL + ++
Sbjct 390 KFIGVLYKDKKLNLLTEYIEGGTLKDFLRNVD-PFPWQQKVRFAKGIASGMAYLHSMCII 448
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------------------------GAL 767
H ++ N L+ + ++D G+
Sbjct 449 HRDLNSHNCLI-------KLDKTVVVADFGLSRLIVEERKRPPVEKAATKKRTLRKSDRK 501
Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--FDGEAPLQSRSPSEKEH 825
R V W+APE L G S +D + FG L EI + R+ +
Sbjct 502 KRYTVVGNPYWMAPEMLNG--KSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLN 559
Query 826 FY-QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ +P P L + C EP RP+F + L
Sbjct 560 VKLFWEKFVPTDCPPAFFPLAAICCKLEPESRPAFSKLEDSFEAL 604
>sp|Q91821|MELK_XENLA Maternal embryonic leucine zipper kinase
OS=Xenopus laevis OX=8355 GN=melk PE=1 SV=2
Length=651
Score = 225 bits (573), Expect = 5e-61, Method: Composition-based stats.
Identities = 72/274 (26%), Positives = 122/274 (45%), Gaps = 26/274 (9%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
Y + +G G F KV L ++ TGE VA+K + + K EID ++ L
Sbjct 12 YYELHETVGTGGFAKVKL----ASHLITGEKVAIKIMDKESLGDDLPRVKTEIDAMKNLS 67
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYL 1014
H+H+ + E K + +V+EY P G L DY+ + + + +F +QI +AY+
Sbjct 68 HQHVCRLYHVIE--TPKKIFMVLEYCPGGELFDYIIAKDRLTEEEARVFFRQIVSAVAYI 125
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H+Q Y HRDL N+L+D D+ +K+ DFGL G +Y+ + + APE ++
Sbjct 126 HSQGYAHRDLKPENLLIDEDQNLKLIDFGLCAKPKGGLDYHLM--TCCGSPAYAAPELIQ 183
Query 1075 EYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ +D+WS GV +Y L+ V+ L + + RG +
Sbjct 184 GKAYIGSEADIWSMGVLMYALMCGYLPFDDD---------------NVMVLYKKIMRG-K 227
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P L+ + + R T ++L+
Sbjct 228 YEIPKWLSPGSVLLLSQMMQVDPKKRITVKHLLN 261
Score = 172 bits (436), Expect = 2e-43, Method: Composition-based stats.
Identities = 48/319 (15%), Positives = 99/319 (31%), Gaps = 39/319 (12%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH- 648
+G G V + G +V +K++D
Sbjct 14 ELHETVGTGGFAKVKLASHLITGE------------------------KVAIKIMDKESL 49
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
D M +SH H+ ++ V + MV EY G L ++ + +
Sbjct 50 GDDLPRVKTEIDAMKNLSHQHVCRLYHVIETPKKIFMVLEYCPGGELFDYIIA-KDRLTE 108
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA-- 766
V +Q+ SA++Y+ ++ H ++ N+L+ +KL D G+
Sbjct 109 EEARVFFRQIVSAVAYIHSQGYAHRDLKPENLLIDE-------DQNLKLIDFGLCAKPKG 161
Query 767 ---LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ APE + G A + + D W G + +
Sbjct 162 GLDYHLMTCCGSPAYAAPELIQGKAY-IGSEADIWSMGVLMYALMCGYLPFDDDNVMVLY 220
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
+ + ++ +P+ P L SQ + +P +R + + +L + ++
Sbjct 221 KKIMRGKYEIPKWLSPGSVLLLSQMMQVDPKKRITVKHLLNHPWLMHGYSCPVEWQSKYP 280
Query 884 SPASDPTVFHKRYLKKIRD 902
D + +
Sbjct 281 LGYIDEDCVTELSVFYKYS 299
>sp|Q9UV51|HOG1_PYRO7 Mitogen-activated protein kinase HOG1 OS=Pyricularia
oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
OX=242507 GN=HOG1 PE=3 SV=1
Length=357
Score = 216 bits (550), Expect = 5e-61, Method: Composition-based stats.
Identities = 67/293 (23%), Positives = 111/293 (38%), Gaps = 31/293 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VA+K + K P +E+ +L+ L HE++
Sbjct 24 QPVGMGAFGLVC----SARDQLTNQNVAIKKIMKPFSTPVLAKRTYRELKLLKHLKHENV 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHE 1174
L + ER P + L++ + R T + L H+
Sbjct 252 SLPKRERQPLKNKFKNADPSAIDLLERMLVFDPKKRITATEALAHEYLTPYHD 304
Score = 129 bits (324), Expect = 5e-31, Method: Composition-based stats.
Identities = 37/231 (16%), Positives = 75/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E D + M + RD+ V +K ++ P +A Y
Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAIKKIMKPFSTPVLAKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLKHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q9LGV5|CIPK1_ORYSJ CBL-interacting protein kinase 1 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK1 PE=2 SV=1
Length=461
Score = 219 bits (559), Expect = 5e-61, Method: Composition-based stats.
Identities = 66/284 (23%), Positives = 113/284 (40%), Gaps = 28/284 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHI 959
LGEG+FGKV + TG A+K L + + ++EI L+ L H ++
Sbjct 24 TLGEGNFGKVKY----ARHLATGAHFAIKILDRNKILSLRFDDQIRREIGTLKLLKHPNV 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQH 1018
++ + + + +V+EYV G L D + + + + QQ+ + ++Y H +
Sbjct 80 VRLHEVAASKTK--IYMVLEYVNGGELFDKIAVKGKLSEHEGRRLFQQLIDAVSYCHDKG 137
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL NVL+D +KI DFGL+ + SP + APE L+ +
Sbjct 138 VYHRDLKPENVLVDRRGNIKISDFGLSALPQHLGNDGLLHTTCGSPN-YIAPEVLQNRGY 196
Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ SD+WS GV LY +L ++ L + + +G+ P
Sbjct 197 DGSLSDIWSCGVILYVMLVGYLPFDD---------------RNLVVLYQKIFKGDT-QIP 240
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
L++ E R + + + Y P
Sbjct 241 KWLSPSARDLLRRILEPNPMKRINIAGIKEH-EWFQKDYTPVVP 283
Score = 175 bits (444), Expect = 8e-46, Method: Composition-based stats.
Identities = 56/306 (18%), Positives = 95/306 (31%), Gaps = 44/306 (14%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647
LG+G V R G+ +K+LD +
Sbjct 20 EIGRTLGEGNFGKVKYARHLATGAHF------------------------AIKILDRNKI 55
Query 648 -HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
+ + H ++ +H V + MV EYV G L + +G +
Sbjct 56 LSLRFDDQIRREIGTLKLLKHPNVVRLHEVAASKTKIYMVLEYVNGGELFDKI-AVKGKL 114
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ QQL A+SY +K + H ++ N+L+ R G IK+SD G+
Sbjct 115 SEHEGRRLFQQLIDAVSYCHDKGVYHRDLKPENVLVDRRG-------NIKISDFGLSALP 167
Query 767 LS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
++APE L + D W G L + G P R+
Sbjct 168 QHLGNDGLLHTTCGSPNYIAPEVLQNRGYD-GSLSDIWSCGVILYVMLV-GYLPFDDRNL 225
Query 821 SEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
+ +P+ P L + L P +R + I + +
Sbjct 226 VVLYQKIFKGDTQIPKWLSPSARDLLRRILEPNPMKRINIAGIKEHEWFQKDYTPVVPYD 285
Query 880 VNPDSP 885
+ D+
Sbjct 286 DDDDNY 291
>sp|Q9M3D8|LRK13_ARATH L-type lectin-domain containing receptor
kinase I.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK13 PE=1
SV=1
Length=664
Score = 225 bits (573), Expect = 5e-61, Method: Composition-based stats.
Identities = 72/299 (24%), Positives = 114/299 (38%), Gaps = 18/299 (6%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
P + +K +G+G FG+V G +AVK L D Q
Sbjct 325 YGPHRFSYKSLYKATNGFRKDCRVGKGGFGEVYKGTLPG-----GRHIAVKRLSHDA-EQ 378
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIG 996
+ E+ + L H +++ G C + E L LV EY+P GSL YL S
Sbjct 379 GMKQFVAEVVTMGNLQHRNLVPLLGYCRRKCE--LLLVSEYMPNGSLDQYLFHEGNPSPS 436
Query 997 LAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
Q + + I ++YLH Q +HRD+ A NV+LD++ ++GDFG+AK G
Sbjct 437 WYQRISILKDIASALSYLHTGTKQVVLHRDIKASNVMLDSEFNGRLGDFGMAKFHDRGTN 496
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELI 1112
+ + APE + +DV++FG L E++ + P L+
Sbjct 497 L--SATAAVGTIGYMAPELITMGT-SMKTDVYAFGAFLLEVICGRRPVEPELPVGKQYLV 553
Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
L + + + + V L C RP E ++ L
Sbjct 554 KWVYECWKEACLFKTRDPRLGVEFLPEEVEMVLKLGLLCTNAMPESRPAMEQVVQYLNQ 612
Score = 216 bits (551), Expect = 4e-58, Method: Composition-based stats.
Identities = 64/308 (21%), Positives = 111/308 (36%), Gaps = 63/308 (20%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ +G+G VY+G L + +K L
Sbjct 338 ATNGFRKDCRVGKGGFGEVYKGTLPGGRH-------------------------IAVKRL 372
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
F M + H +L + G C R E ++V+EY+ +G LD +L E
Sbjct 373 SHDAEQGMKQFVAEVVTMGNLQHRNLVPLLGYCRRKCELLLVSEYMPNGSLDQYLFHEGN 432
Query 705 HVP-MAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
P ++ + + +ASALSYL + ++H ++ N++L +L D
Sbjct 433 PSPSWYQRISILKDIASALSYLHTGTKQVVLHRDIKASNVMLDSEFNG-------RLGDF 485
Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ LS V I ++APE + G S D + FGA LLE+ G P+
Sbjct 486 GMAKFHDRGTNLSATAAVGTIGYMAPELITMGT---SMKTDVYAFGAFLLEVIC-GRRPV 541
Query 816 QSRSPSEKEHFYQRQHRLPEPSC------------------PQLATLTSQCLTYEPTQRP 857
+ P K++ + + + +C + L C P RP
Sbjct 542 EPELPVGKQYLVKWVYECWKEACLFKTRDPRLGVEFLPEEVEMVLKLGLLCTNAMPESRP 601
Query 858 SFRTILRD 865
+ +++
Sbjct 602 AMEQVVQY 609
>sp|Q54YF2|AMPKA_DICDI 5'-AMP-activated serine/threonine-protein
kinase catalytic subunit alpha OS=Dictyostelium discoideum
OX=44689 GN=snfA PE=2 SV=1
Length=727
Score = 226 bits (577), Expect = 5e-61, Method: Composition-based stats.
Identities = 72/275 (26%), Positives = 110/275 (40%), Gaps = 31/275 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK--ADCGPQHRSGWKQEIDILRT 953
+ + LG G FGKV L + TG VA+K L + ++EI ++
Sbjct 30 NYRLDKTLGIGSFGKVKL----AEHIRTGVKVAIKILNRTKIKNLKMDEKIRREIQNMKL 85
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012
H HIIK E + + +VMEYV G L +Y+ ++ + + QQ+ G+
Sbjct 86 FRHPHIIKLYEVIETTTD--IFMVMEYVTGGELFEYIVKNGKLLEDESRRLFQQMISGVD 143
Query 1013 YLHAQHYIHRDLAARNVLLDN-DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
Y H +HRDL N+LLD ++ +KI DFGL+ + +G ++ SP + APE
Sbjct 144 YCHHHMVVHRDLKPENLLLDPINKCIKIADFGLSNMMQDGD---FLKTSCGSPN-YAAPE 199
Query 1072 CLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
+ + DVWS GV LY L L + +
Sbjct 200 VISGKLYAGPEVDVWSCGVILYAFLCAKLPFDDESIPM---------------LFKKIRE 244
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
G PD L+K + R T +
Sbjct 245 GV-FSIPDFVSPSCADLIKKMLVVDPVKRITIHEI 278
Score = 182 bits (461), Expect = 3e-46, Method: Composition-based stats.
Identities = 50/287 (17%), Positives = 92/287 (32%), Gaps = 38/287 (13%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
LG G+ V G ++V +K+L+ +
Sbjct 30 NYRLDKTLGIGSFGKVKLAEHIRTG------------------------VKVAIKILNRT 65
Query 648 ---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ + M H H+ ++ V + MV EYV G L ++ + G
Sbjct 66 KIKNLKMDEKIRREIQNMKLFRHPHIIKLYEVIETTTDIFMVMEYVTGGELFEYIVKN-G 124
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763
+ + QQ+ S + Y + +VH ++ N+LL + IK++D G+
Sbjct 125 KLLEDESRRLFQQMISGVDYCHHHMVVHRDLKPENLLLD------PINKCIKIADFGLSN 178
Query 764 --LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ + APE + G + +D W G L P
Sbjct 179 MMQDGDFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYAFLCAKLPFDDESIPM 237
Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ + +P+ P A L + L +P +R + I
Sbjct 238 LFKKIREGVFSIPDFVSPSCADLIKKMLVVDPVKRITIHEIRNHPWF 284
>sp|Q9FF29|PR5K_ARATH PR5-like receptor kinase OS=Arabidopsis
thaliana OX=3702 GN=PR5K PE=1 SV=1
Length=665
Score = 225 bits (573), Expect = 5e-61, Method: Composition-based stats.
Identities = 68/316 (22%), Positives = 122/316 (39%), Gaps = 23/316 (7%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
T K LG+G FG V Y +G VAVK LK +
Sbjct 317 MLKRYSYTRVKKMTNSFAHVLGKGGFGTV----YKGKLADSGRDVAVKILK--VSEGNGE 370
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQ 999
+ E+ + H +I+ G C ++ +++ ++ E++P GSL Y+ + + +
Sbjct 371 EFINEVASMSRTSHVNIVSLLGFCYEKNKRA--IIYEFMPNGSLDKYISANMSTKMEWER 428
Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
L A I G+ YLH + +H D+ +N+L+D + KI DFGLAK E
Sbjct 429 LYDVAVGISRGLEYLHNRCVTRIVHFDIKPQNILMDENLCPKISDFGLAKLCK-NKESII 487
Query 1057 VREDGDSPVFWYAPECLKE--YKFYYASDVWSFGVTLYELLTHCDSSQSPPT----KFLE 1110
+ APE + + SDV+S+G+ + E++ + + + +
Sbjct 488 SMLHMRGTFGYIAPEMFSKNFGAVSHKSDVYSYGMVVLEMIGAKNIEKVEYSGSNNGSMY 547
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+T + +K ++ + C + S RP +I +L+
Sbjct 548 FPEWVYKDFEKGEITRIFGDSITDEE-EKIAKKLVLVALWCIQMNPSDRPPMIKVIEMLE 606
Query 1171 -TVHEKYQGQAPSVFS 1185
+ P +FS
Sbjct 607 GNLEALQVPPNPLLFS 622
Score = 211 bits (537), Expect = 3e-56, Method: Composition-based stats.
Identities = 60/319 (19%), Positives = 117/319 (37%), Gaps = 61/319 (19%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L + S+ RV + + LG+G VY+G+L G
Sbjct 318 LKRYSYTRVKKMTNSFAHVLGKGGFGTVYKGKLADSGRD--------------------- 356
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K+L S + F + MS+ SH ++ + G C + ++ E++ +G L
Sbjct 357 ---VAVKILKVSEGNG-EEFINEVASMSRTSHVNIVSLLGFCYEKNKRAIIYEFMPNGSL 412
Query 696 DVWLRRERG-HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGT 751
D ++ + VA ++ L YL N+ +VH ++ +NIL+
Sbjct 413 DKYISANMSTKMEWERLYDVAVGISRGLEYLHNRCVTRIVHFDIKPQNILMDE------- 465
Query 752 SPFIKLSDPGVGLGALSREERV------ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ K+SD G+ ++E + ++APE ++S D + +G +L
Sbjct 466 NLCPKISDFGLAKLCKNKESIISMLHMRGTFGYIAPEMFSKNFGAVSHKSDVYSYGMVVL 525
Query 806 EIC---------FDGEAPLQSRSPSEKEHFYQRQH--RL--------PEPSCPQLATLTS 846
E+ + G P +++ R+ E +L +
Sbjct 526 EMIGAKNIEKVEYSGSNNGSMYFPEWVYKDFEKGEITRIFGDSITDEEEKIAKKLVLVAL 585
Query 847 QCLTYEPTQRPSFRTILRD 865
C+ P+ RP ++
Sbjct 586 WCIQMNPSDRPPMIKVIEM 604
>sp|Q9TW45|PAR1_CAEEL Serine/threonine-protein kinase par-1 OS=Caenorhabditis
elegans OX=6239 GN=par-1 PE=1 SV=1
Length=1192
Score = 232 bits (591), Expect = 5e-61, Method: Composition-based stats.
Identities = 76/316 (24%), Positives = 126/316 (40%), Gaps = 29/316 (9%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
+ + + + + H K ++ +G+G+F KV L
Sbjct 128 SSSGRSHPTSGSSSSHARSTGQSGMSSRSAARRNDQDVHVGKYKLLKTIGKGNFAKVKL- 186
Query 915 CYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
+ TG VA+K + P +E+ I++ L H +I+K E E++
Sbjct 187 ---AKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVME--TEQT 241
Query 974 LQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032
L LV+EY G + DYL H + + +QI + YLH+++ IHRDL A N+LLD
Sbjct 242 LYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLD 301
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTL 1091
D +KI DFG + G++ + + APE K+ DVWS GV L
Sbjct 302 QDMNIKIADFGFSNTFSLGNKL----DTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVIL 357
Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
Y L++ + L E + RG + P + +L+K
Sbjct 358 YTLVSGSLPFD---------------GQNLKELRERVLRG-KYRIPFYMSTDCENLLKKF 401
Query 1152 WETEASFRPTFENLIP 1167
R + +N++
Sbjct 402 LVINPQRRSSLDNIMK 417
Score = 197 bits (500), Expect = 6e-50, Method: Composition-based stats.
Identities = 55/287 (19%), Positives = 101/287 (35%), Gaps = 40/287 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ L +G+G V + + G V +K++D +
Sbjct 169 KYKLLKTIGKGNFAKVKLAKHVITGH------------------------EVAIKIIDKT 204
Query 648 HHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ + + +M Q+ H ++ ++ V +V EY G + +L G
Sbjct 205 ALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAH-GR 263
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+ +Q+ SA+ YL +KN++H ++ N+LL + IK++D G
Sbjct 264 MKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQ-------DMNIKIADFGFSNT 316
Query 766 ---ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ P+ APE G +D W G L + G P ++ E
Sbjct 317 FSLGNKLDTFCGSPPYAAPELFSGKKYD-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKE 374
Query 823 KEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
R +R+P L + L P +R S I++D
Sbjct 375 LRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWM 421
>sp|O76411|SCD2_CAEEL ALK tyrosine kinase receptor homolog scd-2
OS=Caenorhabditis elegans OX=6239 GN=scd-2 PE=1 SV=3
Length=1421
Score = 233 bits (593), Expect = 6e-61, Method: Composition-based stats.
Identities = 78/287 (27%), Positives = 127/287 (44%), Gaps = 37/287 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--DCGPQHRSGWKQEIDILRTLYHEHII 960
LG G+FG+V Y +G +AVK + +S + E + T E+++
Sbjct 982 LGRGNFGEVYYGEY------SGVKLAVKMISRTFSASQASQSDFCNEALCMGTFVDENVV 1035
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----------HSIGLAQLLLFAQQICEG 1010
+ G D + + +EY+ G L ++ + ++ L+ + G
Sbjct 1036 RLIGI--DFEKVPYMIALEYMEGGDLLSFVKECRPNQVSLNPFQLAMSDLIKICCDVAAG 1093
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
L Y+HRD+AARN+LL + KI DFG+AK + G EYYR+ P+ W
Sbjct 1094 CKCLETFGYVHRDIAARNILLTTRGPQRVAKIADFGMAKEITYGTEYYRINGRTMMPIKW 1153
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
PE + F SD+WSFGV +E+ + L + + +
Sbjct 1154 TPPEAFIDGVFTTKSDIWSFGVLCWEVFS--------------LGVVPYPNRRNEEVMLM 1199
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
L G RL P P VY LM++CW+T A+ RP F +++ I + + +
Sbjct 1200 LTEGARLEYPYGIPTRVYQLMRDCWKTAAADRPKFVDVVEIFQDIQD 1246
Score = 201 bits (512), Expect = 4e-51, Method: Composition-based stats.
Identities = 59/335 (18%), Positives = 103/335 (31%), Gaps = 52/335 (16%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
S + + I + LG+G VY G +++
Sbjct 967 SLPSISRDSIERGRVLGRGNFGEVYYG--------------------------EYSGVKL 1000
Query 640 VLKVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+K++ + F A M ++ + G+ ++ EY+E G L
Sbjct 1001 AVKMISRTFSASQASQSDFCNEALCMGTFVDENVVRLIGIDFEKVPYMIALEYMEGGDLL 1060
Query 697 VWLRRERG--------HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
+++ R + M+ + + +A+ LE VH ++ RNILL
Sbjct 1061 SFVKECRPNQVSLNPFQLAMSDLIKICCDVAAGCKCLETFGYVHRDIAARNILLT----T 1116
Query 749 EGTSPFIKLSDPGVGLGALSREE-------RVERIPWLAPECLPGGANSLSTAMDKWGFG 801
G K++D G+ E + I W PE G +T D W FG
Sbjct 1117 RGPQRVAKIADFGMAKEITYGTEYYRINGRTMMPIKWTPPEAFIDGV--FTTKSDIWSFG 1174
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859
E+ G P +R E RL P ++ L C RP F
Sbjct 1175 VLCWEVFSLGVVPYPNRRNEEVMLMLTEGARLEYPYGIPTRVYQLMRDCWKTAAADRPKF 1234
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894
++ +Q + + +
Sbjct 1235 VDVVEIFQDIQDDPASVGMPFPIHPAVRATFAHSQ 1269
>sp|A9RWC9|M2K1A_PHYPA Mitogen-activated protein kinase kinase
1a OS=Physcomitrium patens OX=3218 GN=MKK1a PE=2 SV=1
Length=352
Score = 216 bits (549), Expect = 6e-61, Method: Composition-based stats.
Identities = 68/270 (25%), Positives = 112/270 (41%), Gaps = 22/270 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G G V L + T E A+K + + R QE+ I +++
Sbjct 75 LGKGSGGVVQLV----RHKWTNETYALKVIHMNIEETTRKQIVQELKINHASQCPYVVIC 130
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLH-AQH 1018
+ G + +V+EY+ GSL D + I L + +Q+ G+ YLH +H
Sbjct 131 YHAFYNNG--LISIVLEYMDGGSLADIMKELEPKCIKEPNLGVVCKQVLLGLMYLHQTRH 188
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ N+L+++ VKI DFG++ + VR+ + +PE + +
Sbjct 189 IIHRDIKPSNLLVNHKGEVKISDFGVSAVLANSMA---VRDTFVGTCTYMSPERVLGGTY 245
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP- 1137
+ SD+WS G+TL E Q P G +G M L + + P
Sbjct 246 GFDSDIWSLGLTLLECALGKYPYQPP--------GSEEGWMNFYELLQTIVDQPPPVAPA 297
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
D+ E + C + + RPT L+
Sbjct 298 DQFSPEFCSFISACLQKDPKCRPTAAELLN 327
Score = 165 bits (417), Expect = 3e-43, Method: Composition-based stats.
Identities = 54/323 (17%), Positives = 107/323 (33%), Gaps = 49/323 (15%)
Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620
++ G R +T + + + ++ + LG+G+ V
Sbjct 41 MLNKEGIRVVSQTQTSTPAANGNISLSDLETVKVLGKGSGGVV----------------- 83
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVR 679
R + LKV+ + + + + ++ +
Sbjct 84 -------QLVRHKWTNETYALKVIHMNIEETTRKQIVQELKINHASQCPYVVICYHAFYN 136
Query 680 GPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLEN-KNLVHGNVCG 737
+V EY++ G L ++ + VV +Q+ L YL ++++H ++
Sbjct 137 NGLISIVLEYMDGGSLADIMKELEPKCIKEPNLGVVCKQVLLGLMYLHQTRHIIHRDIKP 196
Query 738 RNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSLST 793
N+L+ G +K+SD G + R+ V +++PE + GG
Sbjct 197 SNLLVNHKGE-------VKISDFGVSAVLANSMAVRDTFVGTCTYMSPERVLGGTYGFD- 248
Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP---------EPSCPQLATL 844
D W G TLLE S +FY+ + + P+ +
Sbjct 249 -SDIWSLGLTLLECALGKYPYQPPGSEEGWMNFYELLQTIVDQPPPVAPADQFSPEFCSF 307
Query 845 TSQCLTYEPTQRPSFRTILRDLT 867
S CL +P RP+ +L
Sbjct 308 ISACLQKDPKCRPTAAELLNHPF 330
>sp|Q7FAZ3|LERK1_ORYSJ G-type lectin S-receptor-like serine/threonine-protein
kinase LECRK1 OS=Oryza sativa subsp. japonica
OX=39947 GN=LECRK1 PE=2 SV=1
Length=813
Score = 228 bits (580), Expect = 7e-61, Method: Composition-based stats.
Identities = 67/274 (24%), Positives = 112/274 (41%), Gaps = 14/274 (5%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G G V + D +AVK + P+ + E++ + +H+++++
Sbjct 529 LGAGASGVVYKGQLE---DELKTNIAVKKIDK-LQPETEKEFMVEVETIGQTFHKNLVRL 584
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH---AQH 1018
G C + E+ LV E++ G L L +S + A + G+ YLH ++
Sbjct 585 LGFCNEGAER--LLVYEFMTNGPLNRLLFDNSRPHWNTRVHIALGVARGLLYLHDECSKQ 642
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IH D+ +N+LLD++ + KI DFGLAK + R + APE K
Sbjct 643 IIHCDIKPQNILLDDNLVAKISDFGLAKLLLTNQT--RTNTGIRGTRGYVAPEWFKNIGI 700
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI--GIAQGQMTVLRLTELLERGERLPR 1136
DV+SFGV L EL+ + + + I A R+ L+E +
Sbjct 701 STKVDVYSFGVILLELVCCRRNVELEVVDEEQTIVTYWANDCYRSGRIDLLVEGDDEAIY 760
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
K + C + + S RP + +L
Sbjct 761 NIKKVERFVTVALWCLQEDPSMRPNMLKVTQMLD 794
Score = 215 bits (547), Expect = 1e-56, Method: Composition-based stats.
Identities = 65/334 (19%), Positives = 121/334 (36%), Gaps = 61/334 (18%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
N+ + + + S L L ++ +++ LG G VY+G+L E +
Sbjct 494 KKNIPLSQASSKSQ--LPLKTFTYKELEKATAGFHEILGAGASGVVYKGQLEDELKTN-- 549
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
+ +K +D + F + Q H +L + G C
Sbjct 550 ---------------------IAVKKIDKLQPETEKEFMVEVETIGQTFHKNLVRLLGFC 588
Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGN 734
G E ++V E++ +GPL+ L ++ +A +A L YL +K ++H +
Sbjct 589 NEGAERLLVYEFMTNGPLNRLLFDN-SRPHWNTRVHIALGVARGLLYLHDECSKQIIHCD 647
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGAN 789
+ +NILL + K+SD G+ L+ + R ++APE
Sbjct 648 IKPQNILLD-------DNLVAKISDFGLAKLLLTNQTRTNTGIRGTRGYVAPEWFKNIG- 699
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK------EHFYQRQHRLP--------- 834
+ST +D + FG LLE+ E+ + R R+
Sbjct 700 -ISTKVDVYSFGVILLELVCCRRNVELEVVDEEQTIVTYWANDCYRSGRIDLLVEGDDEA 758
Query 835 ---EPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ T+ CL +P+ RP+ + +
Sbjct 759 IYNIKKVERFVTVALWCLQEDPSMRPNMLKVTQM 792
>sp|O81472|MP3K2_ARATH Mitogen-activated protein kinase kinase
kinase 9 OS=Arabidopsis thaliana OX=3702 GN=MEKK2 PE=1 SV=1
Length=773
Score = 227 bits (578), Expect = 7e-61, Method: Composition-based stats.
Identities = 76/278 (27%), Positives = 122/278 (44%), Gaps = 34/278 (12%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQ---EIDILR 952
+K + L +G FG V G+ AVK + D G Q + +Q EI +L
Sbjct 501 WQKGQLLRQGSFGSVYEAI-----SEDGDFFAVKEVSLLDQGSQAQECIQQLEGEIALLS 555
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
L H++I++Y+G D+ +L + +E V GSL + R+ I + + L+ +QI +G+
Sbjct 556 QLEHQNILRYRG--TDKDGSNLYIFLELVTQGSLLELYRRYQIRDSLISLYTKQILDGLK 613
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
YLH + +IHRD+ +L+D + VK+ DFGLAK R +FW APE
Sbjct 614 YLHHKGFIHRDIKCATILVDANGTVKLADFGLAKVSKLNDIKSRKE-----TLFWMAPEV 668
Query 1073 LKEY---KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
+ + +D+WS G T+ E+ T I + + +
Sbjct 669 INRKDNDGYRSPADIWSLGCTVLEMCTG---------------QIPYSDLEPVEALFRIR 713
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
RG PD + H + C + RPT L+
Sbjct 714 RGTLPEVPDTLSLDARHFILKCLKLNPEERPTATELLN 751
Score = 181 bits (459), Expect = 1e-45, Method: Composition-based stats.
Identities = 61/283 (22%), Positives = 100/283 (35%), Gaps = 37/283 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ L QG+ +VYE +E + D+ +
Sbjct 503 KGQLLRQGSFGSVYEAISEDGDFFAVKEVSLLDQGSQA--------------------QE 542
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
+L+SQ+ H ++ G G + E V G L RR + +
Sbjct 543 CIQQLEGEIALLSQLEHQNILRYRGTDKDGSNLYIFLELVTQGSLLELYRRYQIRDSLIS 602
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--GALS 768
+Q+ L YL +K +H ++ IL+ + +KL+D G+
Sbjct 603 L--YTKQILDGLKYLHHKGFIHRDIKCATILVD-------ANGTVKLADFGLAKVSKLND 653
Query 769 REERVERIPWLAPECLPGGANS-LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
+ R E + W+APE + N + D W G T+LE+C G+ P P E F
Sbjct 654 IKSRKETLFWMAPEVINRKDNDGYRSPADIWSLGCTVLEMC-TGQIPYSDLEPVEAL-FR 711
Query 828 QRQHRLPEPSCPQLAT---LTSQCLTYEPTQRPSFRTILRDLT 867
R+ LPE +CL P +RP+ +L
Sbjct 712 IRRGTLPEVPDTLSLDARHFILKCLKLNPEERPTATELLNHPF 754
>sp|Q6P3R8|NEK5_HUMAN Serine/threonine-protein kinase Nek5 OS=Homo
sapiens OX=9606 GN=NEK5 PE=1 SV=1
Length=708
Score = 226 bits (575), Expect = 7e-61, Method: Composition-based stats.
Identities = 65/281 (23%), Positives = 122/281 (43%), Gaps = 31/281 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961
+G+G FGK L + +K + + P Q + K+E+ +L + H +I+
Sbjct 10 IGQGAFGKAYL----AKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKHPNIVA 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018
+ ++ G L +VMEY G L + R Q+L + QI G+ ++H +
Sbjct 66 FFNSFQENG--RLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRK 123
Query 1019 YIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRD+ A+N+ L + +V K+GDFG+A+ + E R ++ +PE +
Sbjct 124 ILHRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELART---CIGTPYYLSPEICQNKP 180
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ +D+WS G LYEL T + + +L + + P
Sbjct 181 YNNKTDIWSLGCVLYELCTLKHPFE---------------GNNLQQLVLKICQAHFAPIS 225
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKY 1176
E++ L+ ++ RP+ +++ P L+ + KY
Sbjct 226 PGFSRELHSLISQLFQVSPRDRPSINSILKRPFLENLIPKY 266
Score = 166 bits (421), Expect = 3e-41, Method: Composition-based stats.
Identities = 46/283 (16%), Positives = 94/283 (33%), Gaps = 36/283 (13%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ + +GQG Y + + + + ++ P+
Sbjct 1 MDKYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPI------------------ 42
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
A + L+ ++ H ++ +V EY + G L + R+RG
Sbjct 43 ----QEKEASKKEVILLEKMKHPNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGV 98
Query 706 V-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + Q++ L ++ ++ ++H ++ +NI L++ G+ KL D G+
Sbjct 99 LFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLSKNGM------VAKLGDFGIAR 152
Query 765 GALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+ + +L+PE + D W G L E+C +
Sbjct 153 VLNNSMELARTCIGTPYYLSPEICQN--KPYNNKTDIWSLGCVLYELCTLKHPFEGNNLQ 210
Query 821 SEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
Q + +L +L SQ P RPS +I
Sbjct 211 QLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSINSI 253
>sp|C0LGT1|Y5129_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At5g10290 OS=Arabidopsis thaliana OX=3702
GN=At5g10290 PE=1 SV=1
Length=613
Score = 223 bits (569), Expect = 7e-61, Method: Composition-based stats.
Identities = 70/295 (24%), Positives = 112/295 (38%), Gaps = 20/295 (7%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
+ LG+G FGKV VAVK L P + +++
Sbjct 280 WRELQLATDNFSEKNVLGQGGFGKVYKGVL-----PDNTKVAVKRLTDFESPGGDAAFQR 334
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLL 1001
E++++ H ++++ G C Q E+ LV ++ SL L +
Sbjct 335 EVEMISVAVHRNLLRLIGFCTTQTER--LLVYPFMQNLSLAHRLREIKAGDPVLDWETRK 392
Query 1002 LFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
A G YLH IHRD+ A NVLLD D +GDFGLAK V V
Sbjct 393 RIALGAARGFEYLHEHCNPKIIHRDVKAANVLLDEDFEAVVGDFGLAKLV--DVRRTNVT 450
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIA 1115
+ APE L K +DV+ +G+ L EL+T D S+ + L+
Sbjct 451 TQVRGTMGHIAPEYLSTGKSSERTDVFGYGIMLLELVTGQRAIDFSRLEEEDDVLLLDHV 510
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ RL ++++ + + + C + RP ++ +L+
Sbjct 511 KKLEREKRLGAIVDKNLDGEYIKEEVEMMIQVALLCTQGSPEDRPVMSEVVRMLE 565
Score = 187 bits (475), Expect = 1e-48, Method: Composition-based stats.
Identities = 65/362 (18%), Positives = 113/362 (31%), Gaps = 67/362 (19%)
Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + ++ + ++ + LGQG VY+G L
Sbjct 274 QLKRFAWRELQLATDNFSEKNVLGQGGFGKVYKGVLPDN--------------------- 312
Query 633 RGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+V +K L D AF ++S H +L + G C E ++V +++
Sbjct 313 ----TKVAVKRLTDFESPGGDAAFQREVEMISVAVHRNLLRLIGFCTTQTERLLVYPFMQ 368
Query 692 HGPLDVWLRR---ERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745
+ L LR + + +A A YL ++H +V N+LL
Sbjct 369 NLSLAHRLREIKAGDPVLDWETRKRIALGAARGFEYLHEHCNPKIIHRDVKAANVLLDED 428
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800
A + D G+ R V + +APE L G + S D +G+
Sbjct 429 FEAV-------VGDFGLAKLVDVRRTNVTTQVRGTMGHIAPEYLSTGKS--SERTDVFGY 479
Query 801 GATLLEICFDGEAPLQSRSPSEK-------EHFYQRQHRL------------PEPSCPQL 841
G LLE+ A SR E +R+ RL + +
Sbjct 480 GIMLLELVTGQRAIDFSRLEEEDDVLLLDHVKKLEREKRLGAIVDKNLDGEYIKEEVEMM 539
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901
+ C P RP ++R L + + + +R+
Sbjct 540 IQVALLCTQGSPEDRPVMSEVVRMLEGEGLAERWEEWQNVEVTRRHEFERLQRRFDWGED 599
Query 902 DL 903
+
Sbjct 600 SM 601
>sp|Q9S7I6|RPK2_ARATH LRR receptor-like serine/threonine-protein
kinase RPK2 OS=Arabidopsis thaliana OX=3702 GN=RPK2 PE=1
SV=1
Length=1151
Score = 231 bits (590), Expect = 7e-61, Method: Composition-based stats.
Identities = 76/278 (27%), Positives = 110/278 (40%), Gaps = 17/278 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG Y +VA+K L Q + EI L L H +++
Sbjct 880 IGNGGFG----ATYKA-EISQDVVVAIKRLSIG-RFQGVQQFHAEIKTLGRLRHPNLVTL 933
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ---H 1018
G E + LV Y+P G+L ++ R + L A I +AYLH Q
Sbjct 934 IGY--HASETEMFLVYNYLPGGNLEKFIQERSTRDWRVLHKIALDIARALAYLHDQCVPR 991
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRD+ N+LLD+D + DFGLA+ + G + APE +
Sbjct 992 VLHRDVKPSNILLDDDCNAYLSDFGLARLL--GTSETHATTGVAGTFGYVAPEYAMTCRV 1049
Query 1079 YYASDVWSFGVTLYELLTHC---DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+DV+S+GV L ELL+ D S ++ A + R E G
Sbjct 1050 SDKADVYSYGVVLLELLSDKKALDPSFVSYGNGFNIVQWACMLLRQGRAKEFFTAGLWDA 1109
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
P EV HL C S RPT + ++ LK +
Sbjct 1110 GPHDDLVEVLHLAVVCTVDSLSTRPTMKQVVRRLKQLQ 1147
Score = 190 bits (483), Expect = 7e-48, Method: Composition-based stats.
Identities = 47/234 (20%), Positives = 83/234 (35%), Gaps = 43/234 (18%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ +G G Y+ + Q++ V +K L
Sbjct 873 NFNASNLIGNGGFGATYKAEI-------------------------SQDVVVAIKRLSIG 907
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
F+ + ++ H +L + G E +V Y+ G L+ ++ +ER
Sbjct 908 RFQGVQQFHAEIKTLGRLRHPNLVTLIGYHASETEMFLVYNYLPGGNLEKFI-QERSTRD 966
Query 708 MAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+A +A AL+YL ++ ++H +V NILL A LSD G+
Sbjct 967 WRVLHKIALDIARALAYLHDQCVPRVLHRDVKPSNILLDDDCNAY-------LSDFGLAR 1019
Query 765 GALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
+ E ++APE +S D + +G LLE+ D +A
Sbjct 1020 LLGTSETHATTGVAGTFGYVAPEYAMTC--RVSDKADVYSYGVVLLELLSDKKA 1071
>sp|Q25AG3|LERK3_ORYSI G-type lectin S-receptor-like serine/threonine-protein
kinase LECRK3 OS=Oryza sativa subsp. indica
OX=39946 GN=LECRK3 PE=3 SV=2
Length=811
Score = 228 bits (580), Expect = 7e-61, Method: Composition-based stats.
Identities = 70/288 (24%), Positives = 116/288 (40%), Gaps = 14/288 (5%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G G V D G +AVK ++ + + + E+ + +H ++++
Sbjct 527 LGTGASGVVYKGQLQ---DEFGINIAVKKIEK-LQQEAQKEFLVEVQTIGQTFHRNLVRL 582
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH---AQH 1018
G C + E+ LV E++ GSL +L + + + A + G+ YLH +
Sbjct 583 LGFCNEGTER--LLVYEFMSNGSLNTFLFSDTHPHWSLRVQVALGVARGLLYLHEECNKQ 640
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IH D+ +N+LLD++ KI DFGLAK +P + + APE K
Sbjct 641 IIHCDMKPQNILLDDNFAAKISDFGLAKLLPVNQT--QTNTGIRGTRGYVAPEWFKNIGI 698
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPR 1136
DV+SFGV L EL+ + + + L A R+ L+ +
Sbjct 699 TSKVDVYSFGVILLELVCCRKNVELEVLDEEQTILTYWANDCYKCGRIDLLVAGDDEAIF 758
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184
K + C + E S RPT + +L + PS +
Sbjct 759 NIKKVERFVAVALWCLQEEPSMRPTMLKVTQMLDGAVQIPTPPDPSSY 806
Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats.
Identities = 77/408 (19%), Positives = 140/408 (34%), Gaps = 75/408 (18%)
Query 486 TVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCF 545
TV + S+ ++D + + G F S L L ++ G C
Sbjct 430 TVLIKVPRSTNSPSVFSSGSSKWKEDKKYWILGSSLLFGS-SVLVNFLLISVMLFGTYCS 488
Query 546 SLRR--CCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603
R L QP S L P+ S+L +E+ LG G V
Sbjct 489 ITSRKKIQLSQPSNKSGL--------PPKIFTYSELEKATGGFQEV-----LGTGASGVV 535
Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663
Y+G+L+ E + + +K ++ + F +
Sbjct 536 YKGQLQDEF-----------------------GINIAVKKIEKLQQEAQKEFLVEVQTIG 572
Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723
Q H +L + G C G E ++V E++ +G L+ +L H + ++ VA +A L
Sbjct 573 QTFHRNLVRLLGFCNEGTERLLVYEFMSNGSLNTFLF-SDTHPHWSLRVQVALGVARGLL 631
Query 724 YLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ER 775
YL NK ++H ++ +NILL + K+SD G+ + +
Sbjct 632 YLHEECNKQIIHCDMKPQNILLD-------DNFAAKISDFGLAKLLPVNQTQTNTGIRGT 684
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
++APE +++ +D + FG LLE+ + E+ + +
Sbjct 685 RGYVAPEWFKNIG--ITSKVDVYSFGVILLELVCCRKNVELEVLDEEQTILTYWANDCYK 742
Query 836 P------------------SCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ + CL EP+ RP+ + +
Sbjct 743 CGRIDLLVAGDDEAIFNIKKVERFVAVALWCLQEEPSMRPTMLKVTQM 790
>sp|Q9MAM1|CIPK9_ARATH CBL-interacting serine/threonine-protein
kinase 9 OS=Arabidopsis thaliana OX=3702 GN=CIPK9 PE=1 SV=2
Length=447
Score = 219 bits (557), Expect = 8e-61, Method: Composition-based stats.
Identities = 64/276 (23%), Positives = 117/276 (42%), Gaps = 27/276 (10%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRT 953
+ R LGEG F KV N TG+ A+K L + +H+ K+EI ++
Sbjct 18 NYEMGRTLGEGSFAKVKY----AKNTVTGDQAAIKILDREKVFRHKMVEQLKREISTMKL 73
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012
+ H ++++ + + + +V+E V G L D + + + + + QQ+ +
Sbjct 74 IKHPNVVEIIEVMASKTK--IYIVLELVNGGELFDKIAQQGRLKEDEARRYFQQLINAVD 131
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Y H++ HRDL N++LD + ++K+ DFGL+ + E + +P + APE
Sbjct 132 YCHSRGVYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLLHTACGTPN-YVAPEV 190
Query 1073 LKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
L + + A+DVWS GV L+ L+ P ++ L + + +
Sbjct 191 LSDKGYDGAAADVWSCGVILFVLMAGYLPFDEP---------------NLMTLYKRICKA 235
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
E P ++K E R + L+
Sbjct 236 E-FSCPPWFSQGAKRVIKRILEPNPITRISIAELLE 270
Score = 165 bits (418), Expect = 2e-42, Method: Composition-based stats.
Identities = 48/290 (17%), Positives = 90/290 (31%), Gaps = 42/290 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
LG+G+ V + V G + +K+LD
Sbjct 18 NYEMGRTLGEGSFAKVKYAKNTVTGD------------------------QAAIKILDRE 53
Query 648 H---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
H + S M + H ++ + V + +V E V G L + ++G
Sbjct 54 KVFRHKMVEQLKREISTMKLIKHPNVVEIIEVMASKTKIYIVLELVNGGELFDKI-AQQG 112
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ QQL +A+ Y ++ + H ++ N++L + +K+SD G+
Sbjct 113 RLKEDEARRYFQQLINAVDYCHSRGVYHRDLKPENLILD-------ANGVLKVSDFGLSA 165
Query 765 GALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ ++APE L A D W G L + +
Sbjct 166 FSRQVREDGLLHTACGTPNYVAPEVLSDKGYD-GAAADVWSCGVILFVLMAGYLPFDEPN 224
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ + + + P + + L P R S +L D
Sbjct 225 LMTLYKRICKAEFSCPPWFSQGAKRVIKRILEPNPITRISIAELLEDEWF 274
>sp|Q5ZJH6|ULK3_CHICK Serine/threonine-protein kinase ULK3 OS=Gallus
gallus OX=9031 GN=ULK3 PE=2 SV=1
Length=468
Score = 219 bits (558), Expect = 8e-61, Method: Composition-based stats.
Identities = 70/267 (26%), Positives = 109/267 (41%), Gaps = 26/267 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHII 960
LG G + V T E+VAVK + K EI+IL+T+ H HI+
Sbjct 19 RLGTGTYATVYKAYGK---RDTREVVAVKCVSKRSLNRASVENLLTEIEILKTIRHPHIV 75
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ K D + L+ME+ G L ++ R + +F QQ+ + +LH +
Sbjct 76 ELKDFQWDSDH--IYLIMEFCAGGDLSRFIRMRRILPEKVARIFLQQLACALKFLHDHNI 133
Query 1020 IHRDLAARNVLLD--NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
H DL +N+LL + +K+ DFG A+ + E + +R + APE + +
Sbjct 134 SHLDLKPQNILLSTPENPQLKLADFGFAQYMSPWDEKHVLR----GSPLYMAPEMVCRQQ 189
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ D+WS GV LYE L S LE +R +E R P
Sbjct 190 YDARVDLWSVGVILYEALFGRPPFASRSFAELE---------EKIRSDRAIELPSRPPLS 240
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFEN 1164
C L++ E + R +FE
Sbjct 241 PDC----RDLLQRLLERDPLKRISFEE 263
Score = 185 bits (469), Expect = 5e-49, Method: Composition-based stats.
Identities = 64/302 (21%), Positives = 104/302 (34%), Gaps = 41/302 (14%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
LG GT VY+ G+ +E+ V +K +
Sbjct 14 FVLTERLGTGTYATVYKA----------------------YGKRDTREV-VAVKCVSKRS 50
Query 649 HDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
+ A ++ + H H+ + ++ E+ G L ++R R +
Sbjct 51 LNRASVENLLTEIEILKTIRHPHIVELKDFQWDSDHIYLIMEFCAGGDLSRFIRMRRI-L 109
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
P + QQLA AL +L + N+ H ++ +NILL+ +P +KL+D G
Sbjct 110 PEKVARIFLQQLACALKFLHDHNISHLDLKPQNILLS-----TPENPQLKLADFGFAQYM 164
Query 767 LS-REERV--ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
E+ V ++APE + +D W G L E F G P SRS +E
Sbjct 165 SPWDEKHVLRGSPLYMAPEMV--CRQQYDARVDLWSVGVILYEALF-GRPPFASRSFAEL 221
Query 824 EHFYQRQHRLP----EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
E + + P P L + L +P +R SF H
Sbjct 222 EEKIRSDRAIELPSRPPLSPDCRDLLQRLLERDPLKRISFEEFFAHPFVDMEHMPGPESF 281
Query 880 VN 881
Sbjct 282 CK 283
>sp|O94168|SNF1_CANTR Carbon catabolite-derepressing protein kinase
OS=Candida tropicalis OX=5482 GN=SNF1 PE=3 SV=1
Length=619
Score = 223 bits (569), Expect = 8e-61, Method: Composition-based stats.
Identities = 76/292 (26%), Positives = 116/292 (40%), Gaps = 31/292 (11%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
+ + I+ LGEG FGKV L + GTG+ VA+K + +
Sbjct 35 QPIPIDPNVNPANRIGRYQIIKTLGEGSFGKVKL----AQHVGTGQKVALKIINRKTLAK 90
Query 940 HRSG--WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIG 996
++EI LR L H HIIK + + E + +V+E+ L DY+ R +
Sbjct 91 SDMQGRVEREISYLRLLRHPHIIKLYDVIKSKDE--IIMVIEFA-GKELFDYIVQRGKMP 147
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
+ F QQI + Y H +HRDL N+LLD+ VKI DFGL+ + +G+
Sbjct 148 EDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLLLDDQLNVKIADFGLSNIMTDGN---F 204
Query 1057 VREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
++ SP + APE + + DVWS GV LY +L
Sbjct 205 LKTSCGSPN-YAAPEVISGKLYAGPEVDVWSSGVILYVMLCGRLPFDDEF---------- 253
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ L + + G P+ HL+ R T ++
Sbjct 254 -----IPALFKKISNGV-YTLPNYLSPGAKHLLTRMLVVNPLNRITIHEIME 299
Score = 179 bits (454), Expect = 7e-46, Method: Composition-based stats.
Identities = 58/315 (18%), Positives = 107/315 (34%), Gaps = 44/315 (14%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
A+ P N++ +R+ + +I LG+G+ V
Sbjct 34 AQPIPIDPNVNPA--NRIGRYQII--KTLGEGSFGKV----------------------- 66
Query 627 LVPGRDRGQELRVVLKVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
+ G +V LK+++ D+ S + + H H+ ++ V E
Sbjct 67 -KLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHPHIIKLYDVIKSKDEI 125
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
IMV E+ L ++ +RG +P QQ+ +A+ Y +VH ++ N+LL
Sbjct 126 IMVIEFA-GKELFDYI-VQRGKMPEDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLLLD 183
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGF 800
+K++D G+ + + APE + G + +D W
Sbjct 184 DQL-------NVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSS 235
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
G L + P+ + + LP P L ++ L P R +
Sbjct 236 GVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSPGAKHLLTRMLVVNPLNRITIH 295
Query 861 TILRDLTRLQPHNLA 875
I+ D Q
Sbjct 296 EIMEDEWFKQDMPDY 310
>sp|Q5JLD8|CIPK8_ORYSJ CBL-interacting protein kinase 8 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK8 PE=2 SV=1
Length=446
Score = 218 bits (556), Expect = 8e-61, Method: Composition-based stats.
Identities = 68/268 (25%), Positives = 115/268 (43%), Gaps = 29/268 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959
+GEG F KV N +GE VA+K + +H+ K+EI I++ + H ++
Sbjct 18 TIGEGTFAKVKF----AQNTESGESVAMKVVDRSSILKHKMADQIKREISIMKLVRHPNV 73
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018
++ + K + +++E++ G L D + RH + A + QQ+ +G+ + H++
Sbjct 74 VRLHEVLASR--KKIFIILEFITGGELFDKIIRHGRLNEADARRYFQQLIDGVDFCHSKG 131
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N+LLD+ +KI DFGL+ +G R + APE L +
Sbjct 132 VYHRDLKPENLLLDSQGNLKISDFGLSAWPAQGGALLRTT---CGTPNYVAPEVLSHKGY 188
Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
A +D WS GV LY LL P ++L + G++ + P
Sbjct 189 DGALADTWSCGVILYVLLAG-----YLPFDEVDLTTL-YGKIESAEYS----------FP 232
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165
P L+ + R E +
Sbjct 233 AWFPNGAKSLIHRILDPNPDKRIRIEEI 260
Score = 170 bits (430), Expect = 4e-44, Method: Composition-based stats.
Identities = 59/333 (18%), Positives = 103/333 (31%), Gaps = 44/333 (13%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
+ RV + E+ +G+GT V ++ V
Sbjct 6 ALRRVGKYEV--GRTIGEGTFAKV------------------------KFAQNTESGESV 39
Query 640 VLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+KV+D S H +A S+M V H ++ +H V + ++ E++ G L
Sbjct 40 AMKVVDRSSILKHKMADQIKREISIMKLVRHPNVVRLHEVLASRKKIFIILEFITGGELF 99
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
+ R G + A QQL + + +K + H ++ N+LL G +K
Sbjct 100 DKIIRH-GRLNEADARRYFQQLIDGVDFCHSKGVYHRDLKPENLLLDSQG-------NLK 151
Query 757 LSDPGV----GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
+SD G+ G ++APE L D W G L + G
Sbjct 152 ISDFGLSAWPAQGGALLRTTCGTPNYVAPEVLSHKGYD-GALADTWSCGVILY-VLLAGY 209
Query 813 APLQSRSPSEKE-HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P + ++ P +L + L P +R I D +
Sbjct 210 LPFDEVDLTTLYGKIESAEYSFPAWFPNGAKSLIHRILDPNPDKRIRIEEIRNDEWFKKN 269
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
+ + + F L
Sbjct 270 YEPTREIESEEVNLDDVNAAFDDPEEDADHTLD 302
>sp|Q5RDH5|AAPK1_PONAB 5'-AMP-activated protein kinase catalytic
subunit alpha-1 (Fragment) OS=Pongo abelii OX=9601 GN=PRKAA1
PE=2 SV=2
Length=554
Score = 222 bits (565), Expect = 8e-61, Method: Composition-based stats.
Identities = 77/274 (28%), Positives = 111/274 (41%), Gaps = 30/274 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953
+ LG G FGKV + ++ TG VAVK L ++EI L+
Sbjct 21 HYILGDTLGVGTFGKVKVG----KHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKL 76
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012
H HIIK + + +VMEYV G L DY+ ++ + + QQI G+
Sbjct 77 FRHPHIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVD 134
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE
Sbjct 135 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 190
Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + D+WS GV LY LL V L + + G
Sbjct 191 ISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDH---------------VPTLFKKICDG 235
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P V L+K+ + + R T +++
Sbjct 236 IFYT-PQYLNPSVISLLKHMLQVDPMKRATIKDI 268
Score = 182 bits (462), Expect = 2e-47, Method: Composition-based stats.
Identities = 54/298 (18%), Positives = 94/298 (32%), Gaps = 39/298 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
Q RV LG GT V G+ + G
Sbjct 10 KQKHDGRVRIGHYILGDTLGVGTFGKVKVGKHELTGH----------------------- 46
Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+V +K+L+ D+ + H H+ ++ V + MV EYV G
Sbjct 47 -KVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGG 105
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L ++ + G + + QQ+ S + Y +VH ++ N+LL
Sbjct 106 ELFDYICKN-GRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD-------AHM 157
Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ E + APE + G + +D W G L +
Sbjct 158 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSSGVILYALLCG 216
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
P+ + P+ P + +L L +P +R + + I
Sbjct 217 TLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWF 274
>sp|Q9SGP2|HSL1_ARATH Receptor-like protein kinase HSL1 OS=Arabidopsis
thaliana OX=3702 GN=HSL1 PE=1 SV=1
Length=996
Score = 230 bits (586), Expect = 8e-61, Method: Composition-based stats.
Identities = 70/290 (24%), Positives = 121/290 (42%), Gaps = 29/290 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-------KADCGPQ-------HRSGWKQEI 948
+G G GKV GE VAVK L DC P+ ++ E+
Sbjct 682 IGAGASGKVYKVVL-----TNGETVAVKRLWTGSVKETGDCDPEKGYKPGVQDEAFEAEV 736
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQ 1005
+ L + H++I+K CC + K LV EY+P GSL D L +G
Sbjct 737 ETLGKIRHKNIVKLWCCCSTRDCK--LLVYEYMPNGSLGDLLHSSKGGMLGWQTRFKIIL 794
Query 1006 QICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
EG++YLH +HRD+ + N+L+D D ++ DFG+AKAV + +
Sbjct 795 DAAEGLSYLHHDSVPPIVHRDIKSNNILIDGDYGARVADFGVAKAVDLTGKAPKSMSVIA 854
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
+ APE + SD++SFGV + E++T P +L+ +
Sbjct 855 GSCGYIAPEYAYTLRVNEKSDIYSFGVVILEIVTRKRPV-DPELGEKDLVKWVCSTLDQK 913
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ +++ ++ ++ ++ C RP+ ++ +L+ +
Sbjct 914 GIEHVIDPKLDSCFKEEIS-KILNVGLLCTSPLPINRPSMRRVVKMLQEI 962
Score = 186 bits (471), Expect = 1e-46, Method: Composition-based stats.
Identities = 55/325 (17%), Positives = 110/325 (34%), Gaps = 56/325 (17%)
Query 579 LSFHRVDQKE------ITQLSHLGQGTRTNVYEGRLRVEGSGDPEE---GKMDDEDPLVP 629
+SFH++ E + + + +G G VY+ L + + G + + P
Sbjct 660 MSFHKLGFSEHEILESLDEDNVIGAGASGKVYKVVLTNGETVAVKRLWTGSVKETGDCDP 719
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
+ ++ AF + ++ H ++ + C ++V EY
Sbjct 720 EKGYKPGVQ-------------DEAFEAEVETLGKIRHKNIVKLWCCCSTRDCKLLVYEY 766
Query 690 VEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745
+ +G L L +G + + + A LSYL + + +VH ++ NIL+
Sbjct 767 MPNGSLGDLLHSSKGGMLGWQTRFKIILDAAEGLSYLHHDSVPPIVHRDIKSNNILID-- 824
Query 746 GLAEGTSPFIKLSDPGVGLGAL-------SREERVERIPWLAPECLPGGANSLSTAMDKW 798
+++D GV S ++APE ++ D +
Sbjct 825 -----GDYGARVADFGVAKAVDLTGKAPKSMSVIAGSCGYIAPEYA--YTLRVNEKSDIY 877
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQ---RQHRLPEPSCPQLAT-----------L 844
FG +LEI + + Q + P+L + +
Sbjct 878 SFGVVILEIVTRKRPVDPELGEKDLVKWVCSTLDQKGIEHVIDPKLDSCFKEEISKILNV 937
Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869
C + P RPS R +++ L +
Sbjct 938 GLLCTSPLPINRPSMRRVVKMLQEI 962
>sp|P0C431|HOG1_GIBZE Mitogen-activated protein kinase HOG1 OS=Gibberella
zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075
/ NRRL 31084 / PH-1) OX=229533 GN=HOG1 PE=3 SV=1
Length=357
Score = 216 bits (549), Expect = 8e-61, Method: Composition-based stats.
Identities = 66/283 (23%), Positives = 108/283 (38%), Gaps = 29/283 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VAVK + K P +E+ +L+ L HE++
Sbjct 24 QPVGMGAFGLVC----SARDQLTNQNVAVKKIMKPFSTPVLAKRTYRELKLLKHLKHENV 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L + ER P + L++ + R T +
Sbjct 252 SLPKRERQPLRNKFKNADDSAIDLLERMLVFDPKKRITATEAL 294
Score = 129 bits (325), Expect = 4e-31, Method: Composition-based stats.
Identities = 36/213 (17%), Positives = 70/213 (33%), Gaps = 18/213 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E D + M + RD+ V +K ++ P +A Y
Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAVKKIMKPFSTPVLAKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLKHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ APE + +D W G E+
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML 208
>sp|Q14680|MELK_HUMAN Maternal embryonic leucine zipper kinase
OS=Homo sapiens OX=9606 GN=MELK PE=1 SV=3
Length=651
Score = 224 bits (571), Expect = 8e-61, Method: Composition-based stats.
Identities = 72/283 (25%), Positives = 121/283 (43%), Gaps = 26/283 (9%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
+Y + +G G F KV L C + TGEMVA+K + + K
Sbjct 1 MKDYDELLKYYELHETIGTGGFAKVKLAC----HILTGEMVAIKIMDKNTLGSDLPRIKT 56
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQ 1005
EI+ L+ L H+HI + E + + +V+EY P G L DY+ + + + + +
Sbjct 57 EIEALKNLRHQHICQLYHVLETANK--IFMVLEYCPGGELFDYIISQDRLSEEETRVVFR 114
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
QI +AY+H+Q Y HRDL N+L D +K+ DFGL +Y+ + +
Sbjct 115 QIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHL--QTCCGSL 172
Query 1066 FWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+ APE ++ + +DVWS G+ LY L+ V+ L
Sbjct 173 AYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDD---------------NVMAL 217
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + RG + P L++ + + R + +NL+
Sbjct 218 YKKIMRG-KYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLN 259
Score = 170 bits (431), Expect = 9e-43, Method: Composition-based stats.
Identities = 51/319 (16%), Positives = 103/319 (32%), Gaps = 39/319 (12%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
+G G V + G V +K++D +
Sbjct 12 ELHETIGTGGFAKVKLACHILTGEM------------------------VAIKIMDKNTL 47
Query 650 DIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
L + + H H+ ++ V + MV EY G L ++ +
Sbjct 48 GSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEE 107
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV-----G 763
++ V +Q+ SA++Y+ ++ H ++ N+L +KL D G+ G
Sbjct 108 ETRV-VFRQIVSAVAYVHSQGYAHRDLKPENLLFDEY-------HKLKLIDFGLCAKPKG 159
Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ + + APE + G + L + D W G L + +
Sbjct 160 NKDYHLQTCCGSLAYAAPELIQGKSY-LGSEADVWSMGILLYVLMCGFLPFDDDNVMALY 218
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
+ + ++ +P+ P L Q L +P +R S + +L +Q +N
Sbjct 219 KKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNP 278
Query 884 SPASDPTVFHKRYLKKIRD 902
D + + +
Sbjct 279 FIHLDDDCVTELSVHHRNN 297
>sp|Q8BW96|KCC1D_MOUSE Calcium/calmodulin-dependent protein kinase
type 1D OS=Mus musculus OX=10090 GN=Camk1d PE=1 SV=2
Length=385
Score = 216 bits (551), Expect = 9e-61, Method: Composition-based stats.
Identities = 68/269 (25%), Positives = 101/269 (38%), Gaps = 30/269 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG G F +V L TG++ AVK + S + EI +LR + HE+I+
Sbjct 28 TLGTGAFSEVVL----AEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVA 83
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHYI 1020
+ E L LVM+ V G L D + +Q+ + + YLH +
Sbjct 84 LEDIYESPNH--LYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query 1021 HRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
HRDL N+L D + + I DFGL+K +G V + APE L +
Sbjct 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGD----VMSTACGTPGYVAPEVLAQKP 197
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ A D WS GV Y LL + ++L+ P
Sbjct 198 YSKAVDCWSIGVIAYILLCGYPPF--------------YDENDSKLFEQILKAEYEFDSP 243
Query 1138 --DKCPCEVYHLMKNCWETEASFRPTFEN 1164
D ++N E + + R T E
Sbjct 244 YWDDISDSAKDFIRNLMEKDPNKRYTCEQ 272
Score = 149 bits (376), Expect = 1e-37, Method: Composition-based stats.
Identities = 43/314 (14%), Positives = 89/314 (28%), Gaps = 45/314 (14%)
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
+ R S + ++ LG G + V
Sbjct 1 MARENGESSSSWKKQAEDIKKI----FEFKETLGTGAFSEV------------------- 37
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGP 681
V ++ +K + + +++ ++ H ++ + +
Sbjct 38 -----VLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPN 92
Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
+V + V G L + E+G + +Q+ A+ YL +VH ++ N+L
Sbjct 93 HLYLVMQLVSGGELFDRI-VEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLL 151
Query 742 LARLGLAEGTSPFIKLSDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKW 798
++ I +SD G+ ++APE L S A+D W
Sbjct 152 ----YYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQ--KPYSKAVDCW 205
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQR-----QHRLPEPSCPQLATLTSQCLTYEP 853
G I G P + S+ + + + +P
Sbjct 206 SIGVIAY-ILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264
Query 854 TQRPSFRTILRDLT 867
+R + R
Sbjct 265 NKRYTCEQAARHPW 278
>sp|Q9LMN7|WAK5_ARATH Wall-associated receptor kinase 5 OS=Arabidopsis
thaliana OX=3702 GN=WAK5 PE=2 SV=1
Length=733
Score = 226 bits (575), Expect = 9e-61, Method: Composition-based stats.
Identities = 71/279 (25%), Positives = 115/279 (41%), Gaps = 18/279 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G G V +VA+K + Q + E+ +L + H +++K
Sbjct 414 LGQGGQGTVYKGILQ-----DNSIVAIKKARLGDRSQ-VEQFINEVLVLSQINHRNVVKL 467
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQ- 1017
GCC + E L LV E++ G+L D+L S+ L A ++ +AYLH+
Sbjct 468 LGCCLE-TEVPL-LVYEFISSGTLFDHLHGSMFDSSLTWEHRLRIAIEVAGTLAYLHSYA 525
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
IHRD+ N+LLD + K+ DFG ++ +P E G + + PE
Sbjct 526 SIPIIHRDVKTANILLDENLTAKVADFGASRLIPMDQEQLTTMVQG--TLGYLDPEYYNT 583
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
SDV+SFGV L ELL+ + P L+ M RL E+++
Sbjct 584 GLLNEKSDVYSFGVVLMELLSGEKALCFERPQSSKHLVSYFVSAMKENRLHEIIDGQVMN 643
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ E + C RP+ + + L+ +
Sbjct 644 EYNQREIQESARIAVECTRIMGEERPSMKEVAAELEALR 682
Score = 205 bits (521), Expect = 9e-54, Method: Composition-based stats.
Identities = 67/360 (19%), Positives = 128/360 (36%), Gaps = 65/360 (18%)
Query 559 SNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616
++I R + A P +++ + + + LGQG + VY+G L+
Sbjct 376 GGMLIQRLSGAGPSNVDVKIFTEEGMKEATDGYNESRILGQGGQGTVYKGILQDNSI--- 432
Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676
V +K F ++SQ++H ++ + G
Sbjct 433 ----------------------VAIKKARLGDRSQVEQFINEVLVLSQINHRNVVKLLGC 470
Query 677 CVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLV 731
C+ ++V E++ G L L + W ++ +A ++A L+YL + ++
Sbjct 471 CLETEVPLLVYEFISSGTLFDHLHGSMFDSSLTWEHRLRIAIEVAGTLAYLHSYASIPII 530
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPG 786
H +V NILL + K++D G +E++ + +L PE
Sbjct 531 HRDVKTANILLDE-------NLTAKVADFGASRLIPMDQEQLTTMVQGTLGYLDPEYYNT 583
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY------QRQHRLPEPSCPQ 840
G L+ D + FG L+E+ GE L P +H +++RL E Q
Sbjct 584 GL--LNEKSDVYSFGVVLMELLS-GEKALCFERPQSSKHLVSYFVSAMKENRLHEIIDGQ 640
Query 841 L------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASD 888
+ A + +C +RPS + + +L L+ +
Sbjct 641 VMNEYNQREIQESARIAVECTRIMGEERPSMKEVAAELEALRVKTTKHQWSDQYPKEVEH 700
>sp|C4YRB7|STE20_CANAW Serine/threonine-protein kinase CST20 OS=Candida
albicans (strain WO-1) OX=294748 GN=CST20 PE=3 SV=2
Length=1224
Score = 231 bits (590), Expect = 9e-61, Method: Composition-based stats.
Identities = 62/266 (23%), Positives = 119/266 (45%), Gaps = 22/266 (8%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G G V L +D + +VA+K + + P+ + EI +++ H +I+
Sbjct 952 KIGQGASGGVFLA-HDVRDKSN--IVAIKQMNLEQQPK-KELIINEILVMKGSSHPNIVN 1007
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
+ +G+ L ++MEY+ GSL D + + Q+ + ++ +G+ +LH++ IH
Sbjct 1008 FIDSYLLKGD--LWVIMEYMEGGSLTDIVTHSVMTEGQIGVVCRETLKGLKFLHSKGVIH 1065
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RD+ + N+LL+ D +KI DFG + +E R +W APE + ++
Sbjct 1066 RDIKSDNILLNMDGNIKITDFGFCAQI---NEINSKRITMVGTPYWMAPEIVSRKEYGPK 1122
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
DVWS G+ + E+L + T L IA +L P+
Sbjct 1123 VDVWSLGIMIIEML-EGEPPYLNETPLRALYLIATNGTP------------KLKDPESLS 1169
Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167
++ + C + + + R + L+
Sbjct 1170 YDIRKFLAWCLQVDFNKRADADELLH 1195
Score = 181 bits (458), Expect = 9e-45, Method: Composition-based stats.
Identities = 53/296 (18%), Positives = 96/296 (32%), Gaps = 44/296 (15%)
Query 585 DQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
D E+ L +GQG V+ R + V +K
Sbjct 942 DPNELYVDLVKIGQGASGGVFLAH-----------------------DVRDKSNIVAIKQ 978
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
++ +M SH ++ + + ++ EY+E G L +
Sbjct 979 MNLEQQPKKELIINEILVMKGSSHPNIVNFIDSYLLKGDLWVIMEYMEGGSLTDIVTHS- 1037
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ VV ++ L +L +K ++H ++ NILL IK++D G
Sbjct 1038 -VMTEGQIGVVCRETLKGLKFLHSKGVIHRDIKSDNILLN-------MDGNIKITDFGFC 1089
Query 764 LGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
R V W+APE + +D W G ++E+ +GE P + +
Sbjct 1090 AQINEINSKRITMVGTPYWMAPEIVS--RKEYGPKVDVWSLGIMIIEML-EGEPPYLNET 1146
Query 820 PSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P + PE + + CL + +R +L D +
Sbjct 1147 PLRALYLIATNGTPKLKDPESLSYDIRKFLAWCLQVDFNKRADADELLHDNFITEC 1202
>sp|Q69SP5|EREC1_ORYSJ LRR receptor-like serine/threonine-protein
kinase ER1 OS=Oryza sativa subsp. japonica OX=39947 GN=ER1
PE=1 SV=1
Length=978
Score = 229 bits (585), Expect = 9e-61, Method: Composition-based stats.
Identities = 73/336 (22%), Positives = 128/336 (38%), Gaps = 23/336 (7%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
L P P F+ + +L +N + + L + +
Sbjct 592 LMILVAVCRPHSPPVFKDVSVSKPVSNVPPKLVILHMNLSLLVYEDIMTMTENLSEKYII 651
Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963
G G V + VAVK L A PQ ++ E++ + ++ H +++ +
Sbjct 652 GYGASSTVYKCVSKNR-----KPVAVKKLYAHY-PQSFKEFETELETVGSIKHRNLVSLQ 705
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLH--- 1015
G L +Y+ GSL D L + + L A +G+AYLH
Sbjct 706 GYSLSPVGN--LLFYDYMENGSLWDVLHEGPTKKKKLDWETRLRIALGAAQGLAYLHHDC 763
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ IHRD+ ++N+LLD D + DFG+AK++ + + + PE +
Sbjct 764 SPRIIHRDVKSKNILLDKDYEAHLTDFGIAKSLCVSKTH--TSTYVMGTIGYIDPEYART 821
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ SDV+S+G+ L ELLT P L + + + E ++
Sbjct 822 SRLNEKSDVYSYGIVLLELLTGK----KPVDNECNLHHLILSKTANNAVMETVDPDIADT 877
Query 1136 RPD-KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
D +V+ L C + + S RPT ++ +L
Sbjct 878 CKDLGEVKKVFQLALLCTKRQPSDRPTMHEVVRVLD 913
Score = 189 bits (481), Expect = 7e-48, Method: Composition-based stats.
Identities = 63/378 (17%), Positives = 124/378 (33%), Gaps = 66/378 (17%)
Query 543 DCFSLRRCCLPQ-PGETSNLIIMRGARASPRTL-----NLSQLSFHRVDQ--KEITQLSH 594
L C P P ++ + + P L NLS L + + + +++
Sbjct 591 LLMILVAVCRPHSPPVFKDVSVSKPVSNVPPKLVILHMNLSLLVYEDIMTMTENLSEKYI 650
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
+G G + VY+ + V +K L +
Sbjct 651 IGYGASSTVYKCVSKNRKP-------------------------VAVKKLYAHYPQSFKE 685
Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR---ERGHVPMAWK 711
F + + H +L + G + N++ +Y+E+G L L ++ + +
Sbjct 686 FETELETVGSIKHRNLVSLQGYSLSPVGNLLFYDYMENGSLWDVLHEGPTKKKKLDWETR 745
Query 712 MVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG--- 765
+ +A A L+YL + ++H +V +NILL + A L+D G+
Sbjct 746 LRIALGAAQGLAYLHHDCSPRIIHRDVKSKNILLDKDYEAH-------LTDFGIAKSLCV 798
Query 766 --ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ + I ++ PE + L+ D + +G LLE+ + +
Sbjct 799 SKTHTSTYVMGTIGYIDPEYART--SRLNEKSDVYSYGIVLLELLTGKKPVDNECNLHHL 856
Query 824 EHFYQRQHRLPEPSCPQLAT-------------LTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ + E P +A L C +P+ RP+ ++R L L
Sbjct 857 ILSKTANNAVMETVDPDIADTCKDLGEVKKVFQLALLCTKRQPSDRPTMHEVVRVLDCLV 916
Query 871 PHNLADVLTVNPDSPASD 888
+ P
Sbjct 917 RPDPPPKSAQQLAMPQRP 934
>sp|P0CY24|STE20_CANAL Serine/threonine-protein kinase CST20 OS=Candida
albicans (strain SC5314 / ATCC MYA-2876) OX=237561
GN=CST20 PE=3 SV=1
Length=1228
Score = 231 bits (590), Expect = 9e-61, Method: Composition-based stats.
Identities = 62/266 (23%), Positives = 119/266 (45%), Gaps = 22/266 (8%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G G V L +D + +VA+K + + P+ + EI +++ H +I+
Sbjct 956 KIGQGASGGVFLA-HDVRDKSN--IVAIKQMNLEQQPK-KELIINEILVMKGSSHPNIVN 1011
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
+ +G+ L ++MEY+ GSL D + + Q+ + ++ +G+ +LH++ IH
Sbjct 1012 FIDSYLLKGD--LWVIMEYMEGGSLTDIVTHSVMTEGQIGVVCRETLKGLKFLHSKGVIH 1069
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RD+ + N+LL+ D +KI DFG + +E R +W APE + ++
Sbjct 1070 RDIKSDNILLNMDGNIKITDFGFCAQI---NEINSKRITMVGTPYWMAPEIVSRKEYGPK 1126
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
DVWS G+ + E+L + T L IA +L P+
Sbjct 1127 VDVWSLGIMIIEML-EGEPPYLNETPLRALYLIATNGTP------------KLKDPESLS 1173
Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167
++ + C + + + R + L+
Sbjct 1174 YDIRKFLAWCLQVDFNKRADADELLH 1199
Score = 181 bits (458), Expect = 9e-45, Method: Composition-based stats.
Identities = 53/296 (18%), Positives = 96/296 (32%), Gaps = 44/296 (15%)
Query 585 DQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
D E+ L +GQG V+ R + V +K
Sbjct 946 DPNELYVDLVKIGQGASGGVFLAH-----------------------DVRDKSNIVAIKQ 982
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
++ +M SH ++ + + ++ EY+E G L +
Sbjct 983 MNLEQQPKKELIINEILVMKGSSHPNIVNFIDSYLLKGDLWVIMEYMEGGSLTDIVTHS- 1041
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ VV ++ L +L +K ++H ++ NILL IK++D G
Sbjct 1042 -VMTEGQIGVVCRETLKGLKFLHSKGVIHRDIKSDNILLN-------MDGNIKITDFGFC 1093
Query 764 LGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
R V W+APE + +D W G ++E+ +GE P + +
Sbjct 1094 AQINEINSKRITMVGTPYWMAPEIVS--RKEYGPKVDVWSLGIMIIEML-EGEPPYLNET 1150
Query 820 PSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P + PE + + CL + +R +L D +
Sbjct 1151 PLRALYLIATNGTPKLKDPESLSYDIRKFLAWCLQVDFNKRADADELLHDNFITEC 1206
>sp|P0CY23|STE20_CANAX Serine/threonine-protein kinase CST20 OS=Candida
albicans OX=5476 GN=CST20 PE=3 SV=1
Length=1230
Score = 231 bits (590), Expect = 9e-61, Method: Composition-based stats.
Identities = 62/266 (23%), Positives = 119/266 (45%), Gaps = 22/266 (8%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G G V L +D + +VA+K + + P+ + EI +++ H +I+
Sbjct 958 KIGQGASGGVFLA-HDVRDKSN--IVAIKQMNLEQQPK-KELIINEILVMKGSSHPNIVN 1013
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
+ +G+ L ++MEY+ GSL D + + Q+ + ++ +G+ +LH++ IH
Sbjct 1014 FIDSYLLKGD--LWVIMEYMEGGSLTDIVTHSVMTEGQIGVVCRETLKGLKFLHSKGVIH 1071
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RD+ + N+LL+ D +KI DFG + +E R +W APE + ++
Sbjct 1072 RDIKSDNILLNMDGNIKITDFGFCAQI---NEINSKRITMVGTPYWMAPEIVSRKEYGPK 1128
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
DVWS G+ + E+L + T L IA +L P+
Sbjct 1129 VDVWSLGIMIIEML-EGEPPYLNETPLRALYLIATNGTP------------KLKDPESLS 1175
Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167
++ + C + + + R + L+
Sbjct 1176 YDIRKFLAWCLQVDFNKRADADELLH 1201
Score = 181 bits (458), Expect = 9e-45, Method: Composition-based stats.
Identities = 53/296 (18%), Positives = 96/296 (32%), Gaps = 44/296 (15%)
Query 585 DQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
D E+ L +GQG V+ R + V +K
Sbjct 948 DPNELYVDLVKIGQGASGGVFLAH-----------------------DVRDKSNIVAIKQ 984
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
++ +M SH ++ + + ++ EY+E G L +
Sbjct 985 MNLEQQPKKELIINEILVMKGSSHPNIVNFIDSYLLKGDLWVIMEYMEGGSLTDIVTHS- 1043
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ VV ++ L +L +K ++H ++ NILL IK++D G
Sbjct 1044 -VMTEGQIGVVCRETLKGLKFLHSKGVIHRDIKSDNILLN-------MDGNIKITDFGFC 1095
Query 764 LGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
R V W+APE + +D W G ++E+ +GE P + +
Sbjct 1096 AQINEINSKRITMVGTPYWMAPEIVS--RKEYGPKVDVWSLGIMIIEML-EGEPPYLNET 1152
Query 820 PSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P + PE + + CL + +R +L D +
Sbjct 1153 PLRALYLIATNGTPKLKDPESLSYDIRKFLAWCLQVDFNKRADADELLHDNFITEC 1208
>sp|Q00532|CDKL1_HUMAN Cyclin-dependent kinase-like 1 OS=Homo
sapiens OX=9606 GN=CDKL1 PE=1 SV=8
Length=357
Score = 215 bits (548), Expect = 9e-61, Method: Composition-based stats.
Identities = 67/293 (23%), Positives = 125/293 (43%), Gaps = 29/293 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960
+GEG +G V + N TG++VA+K L+++ P + +EI +L+ L H +++
Sbjct 9 KIGEGSYGVV----FKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLV 64
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ + L LV EY L + + + + Q + + + H +
Sbjct 65 NLLEVFRRK--RRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNC 122
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEYKF 1078
IHRD+ N+L+ ++K+ DFG A+ + +YY D + ++ +PE L + ++
Sbjct 123 IHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYY---TDYVATRWYRSPELLVGDTQY 179
Query 1079 YYASDVWSFGVTLYELLTHCD-----SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
DVW+ G ELL+ S + +G + + T G +
Sbjct 180 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVK 239
Query 1134 LPRPDKC-PCEVY---------HLMKNCWETEASFRPTFENLI--PILKTVHE 1174
+P P+ P E+ L+K C + + R T E L+ P + + E
Sbjct 240 IPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIRE 292
Score = 154 bits (388), Expect = 2e-39, Method: Composition-based stats.
Identities = 50/250 (20%), Positives = 87/250 (35%), Gaps = 40/250 (16%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ ++ +G+G+ V++ R R G V +K
Sbjct 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQ------------------------IVAIKKFL 36
Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
S D I ++ Q+ H +L + V R +V EY +H L R +R
Sbjct 37 ESEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQR 96
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
G VP + Q A+++ N +H +V NIL+ + IKL D G
Sbjct 97 G-VPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENILITK-------HSVIKLCDFGFA 148
Query 764 LGAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ V + +PE L G +D W G E+ G +S
Sbjct 149 RLLTGPSDYYTDYVATRWYRSPELLV-GDTQYGPPVDVWAIGCVFAELLS-GVPLWPGKS 206
Query 820 PSEKEHFYQR 829
++ + ++
Sbjct 207 DVDQLYLIRK 216
>sp|Q6R2K1|SRF5_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 5 OS=Arabidopsis
thaliana OX=3702 GN=SRF5 PE=1 SV=1
Length=699
Score = 225 bits (573), Expect = 9e-61, Method: Composition-based stats.
Identities = 70/284 (25%), Positives = 117/284 (41%), Gaps = 26/284 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI-LRTLYHEHIIK 961
LGEG G+V Y G +AVK + + +S I + L + H++I +
Sbjct 410 LGEGSIGRVYRAKY-----SDGRTLAVKKIDSTLFDSGKSEGITPIVMSLSKIRHQNIAE 464
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMAYLH- 1015
G C +QG LV EY GSL ++L + + A + YLH
Sbjct 465 LVGYCSEQGHN--MLVYEYFRNGSLHEFLHLSDCFSKPLTWNTRVRIALGTARAVEYLHE 522
Query 1016 --AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ +H+++ + N+LLD D ++ D+GL+K +R + + APE
Sbjct 523 ACSPSVMHKNIKSSNILLDADLNPRLSDYGLSKFY--------LRTSQNLGEGYNAPEAR 574
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQM-TVLRLTELLERG 1131
+ SDV+SFGV + ELLT P L+ A Q+ + L+ + +
Sbjct 575 DPSAYTPKSDVYSFGVVMLELLTGRVPFDGEKPRPERSLVRWATPQLHDIDALSNIADPA 634
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
P K ++ C + E FRP ++ L + ++
Sbjct 635 LHGLYPPKSLSRFADIIALCVQVEPEFRPPMSEVVEALVRMVQR 678
Score = 177 bits (449), Expect = 9e-45, Method: Composition-based stats.
Identities = 61/334 (18%), Positives = 115/334 (34%), Gaps = 63/334 (19%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
S R+ +LS + + + LG+G+ VY + +
Sbjct 384 TSTRSAVEFELSDLQSATANFSPGNLLGEGSIGRVYRAKYSDGRTL-------------- 429
Query 629 PGRDRGQELRVVLKVLDPSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
+K +D + D + +S++ H ++A + G C N++V
Sbjct 430 -----------AVKKIDSTLFDSGKSEGITPIVMSLSKIRHQNIAELVGYCSEQGHNMLV 478
Query 687 TEYVEHGPLDVWLRRER---GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNI 740
EY +G L +L + ++ +A A A+ YL + +++H N+ NI
Sbjct 479 YEYFRNGSLHEFLHLSDCFSKPLTWNTRVRIALGTARAVEYLHEACSPSVMHKNIKSSNI 538
Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800
LL +LSD G+ L + + + APE ++ + D + F
Sbjct 539 LLD-------ADLNPRLSDYGLSKFYLRTSQNLGE-GYNAPEA--RDPSAYTPKSDVYSF 588
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQR-------------------QHRLPEPSCPQL 841
G +LE+ G P P + + P S +
Sbjct 589 GVVMLELL-TGRVPFDGEKPRPERSLVRWATPQLHDIDALSNIADPALHGLYPPKSLSRF 647
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
A + + C+ EP RP ++ L R+ +
Sbjct 648 ADIIALCVQVEPEFRPPMSEVVEALVRMVQRSSM 681
>sp|Q09892|HOG1_SCHPO Mitogen-activated protein kinase sty1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=sty1 PE=1 SV=1
Length=349
Score = 215 bits (548), Expect = 9e-61, Method: Composition-based stats.
Identities = 65/306 (21%), Positives = 115/306 (38%), Gaps = 29/306 (9%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADC 936
+ + ++ +G G FG V + TG VAVK + K
Sbjct 1 MAEFIRTQIFGTCFEITTRYSDLQPIGMGAFGLVC----SAKDQLTGMNVAVKKIMKPFS 56
Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996
P +E+ +L+ L HE+II E + V E + L L +
Sbjct 57 TPVLAKRTYRELKLLKHLRHENIISLSDIFISPFED-IYFVTELL-GTDLHRLLTSRPLE 114
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
+ F QI G+ ++H+ IHRDL N+L++ + +KI DFGLA+ Y
Sbjct 115 TQFIQYFLYQILRGLKFVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY- 173
Query 1057 VREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLE 1110
S ++ APE + K+ D+WS G E++ + + E
Sbjct 174 -----VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQFSIITE 228
Query 1111 LIGIAQGQM-------TVLRLTELLERGERLPRPD---KCPCEVYHLMKNCWETEASFRP 1160
L+G ++ LR + L + E++P + + L++ + R
Sbjct 229 LLGTPPMEVIETICSKNTLRFVQSLPQKEKVPFAEKFKNADPDAIDLLEKMLVFDPRKRI 288
Query 1161 TFENLI 1166
+ + +
Sbjct 289 SAADAL 294
Score = 134 bits (336), Expect = 1e-32, Method: Composition-based stats.
Identities = 35/231 (15%), Positives = 77/231 (33%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E D + M + +D+ + V +K ++ P +A Y
Sbjct 10 FGTCFE---ITTRYSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPFEDIYFVTELL-GTDLHRLLTSR--PLETQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L ++ + ++H ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKFVHSAGVIHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + + +D W G E+ +G+ R +
Sbjct 177 RYYRAPE-IMLTWQKYNVEVDIWSAGCIFAEMI-EGKPLFPGRDHVNQFSI 225
>sp|P34117|CDK5_DICDI Cyclin-dependent kinase 5 homolog OS=Dictyostelium
discoideum OX=44689 GN=cdk5 PE=2 SV=2
Length=292
Score = 213 bits (542), Expect = 9e-61, Method: Composition-based stats.
Identities = 72/288 (25%), Positives = 120/288 (42%), Gaps = 29/288 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-GWKQEIDILR 952
KI LGEG +G V Y N TGE+VA+K ++ D + +EI +L+
Sbjct 1 MEKYSKIEKLGEGTYGIV----YKAKNRETGEIVALKRIRLDSEDEGVPCTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEG 1010
L H +I++ E+ L LV EY+ L+ YL I + F Q+ +G
Sbjct 57 ELKHPNIVRLHDVI--HTERKLTLVFEYLDQ-DLKKYLDECGGEISKPTIKSFMYQLLKG 113
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
+A+ H +HRDL +N+L++ +K+ DFGLA+A Y +++ AP
Sbjct 114 VAFCHDHRVLHRDLKPQNLLINRKGELKLADFGLARAFGIPVRTYSHE---VVTLWYRAP 170
Query 1071 ECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTVLRL 1124
+ L K+ D+WS G E+ + + +++G + + +
Sbjct 171 DVLMGSRKYSTPIDIWSAGCIFAEMASGRPLFPGSGTSDQLFRIFKILGTPNEE-SWPSI 229
Query 1125 TELLERGERLPR-PDKCPCEVYH--------LMKNCWETEASFRPTFE 1163
TEL E P P + H L+ + + + R T
Sbjct 230 TELPEYKTDFPVHPAHQLSSIVHGLDEKGLNLLSKMLQYDPNQRITAA 277
Score = 167 bits (423), Expect = 8e-45, Method: Composition-based stats.
Identities = 51/265 (19%), Positives = 98/265 (37%), Gaps = 39/265 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-- 643
++ +++ LG+GT VY+ + R G V LK
Sbjct 1 MEKYSKIEKLGEGTYGIVYKAKNRETGE------------------------IVALKRIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
LD + SL+ ++ H ++ +H V + +V EY++ L +L
Sbjct 37 LDSEDEGVPCTAIREISLLKELKHPNIVRLHDVIHTERKLTLVFEYLDQ-DLKKYLDECG 95
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
G + QL +++ + ++H ++ +N+L+ R G +KL+D G+
Sbjct 96 GEISKPTIKSFMYQLLKGVAFCHDHRVLHRDLKPQNLLINRKGE-------LKLADFGLA 148
Query 764 LG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ V + + AP+ L G+ ST +D W G E+ S +
Sbjct 149 RAFGIPVRTYSHEVVTLWYRAPDVLM-GSRKYSTPIDIWSAGCIFAEMASGRPLFPGSGT 207
Query 820 PSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ E S P + L
Sbjct 208 SDQLFRIFKILGTPNEESWPSITEL 232
>sp|Q1KTF2|HOG1_ZYMTI Mitogen-activated protein kinase Hog1 OS=Zymoseptoria
tritici (strain CBS 115943 / IPO323) OX=336722
GN=Hog1 PE=3 SV=2
Length=357
Score = 215 bits (548), Expect = 1e-60, Method: Composition-based stats.
Identities = 65/276 (24%), Positives = 108/276 (39%), Gaps = 29/276 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + TG+ VAVK + K P +E+ +L+ L HE++
Sbjct 24 QPVGMGAFGLVC----SAKDQLTGQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLKHENV 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
D+WS G E+L + + +L+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITDLLGTPPDDVISTICSENTLRFVQ 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFR 1159
L + ER P + + L++ + R
Sbjct 252 SLPKRERQPLKNKFKNADPQAIELLERMLVFDPRKR 287
Score = 133 bits (334), Expect = 2e-32, Method: Composition-based stats.
Identities = 35/234 (15%), Positives = 74/234 (32%), Gaps = 19/234 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + +D+ V +K ++ P ++ Y
Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSAKDQLTGQAVAVKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLKHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
+ APE + +D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSIITD 228
>sp|C0LGH2|Y1561_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g56130 OS=Arabidopsis thaliana OX=3702
GN=At1g56130 PE=2 SV=2
Length=1032
Score = 230 bits (586), Expect = 1e-60, Method: Composition-based stats.
Identities = 78/317 (25%), Positives = 127/317 (40%), Gaps = 18/317 (6%)
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920
TI + R + V P + LGEG FG V N
Sbjct 658 TIRKRRKRYTDDEELLGMDVKPYIFTYSELKSATQDFDPSNKLGEGGFGPVYKG-----N 712
Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
G +VAVK L Q + + EI + ++ H +++K GCC + + LV EY
Sbjct 713 LNDGRVVAVKLLSVG-SRQGKGQFVAEIVAISSVLHRNLVKLYGCCFEGEHR--MLVYEY 769
Query 981 VPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDND 1034
+P GSL L + + + G+ YLH + +HRD+ A N+LLD+
Sbjct 770 LPNGSLDQALFGDKTLHLDWSTRYEICLGVARGLVYLHEEASVRIVHRDVKASNILLDSR 829
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
+ +I DFGLAK + + R G + + APE +DV++FGV EL
Sbjct 830 LVPQISDFGLAKLYDDKKTHISTRVAG--TIGYLAPEYAMRGHLTEKTDVYAFGVVALEL 887
Query 1095 LTHCDSSQSPPTKFLE-LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
++ +S + + L+ A R EL++ + + + C +
Sbjct 888 VSGRPNSDENLEEEKKYLLEWAWNLHEKSRDIELIDDKLT-DFNMEEAKRMIGIALLCTQ 946
Query 1154 TEASFRPTFENLIPILK 1170
T + RP ++ +L
Sbjct 947 TSHALRPPMSRVVAMLS 963
Score = 220 bits (560), Expect = 2e-57, Method: Composition-based stats.
Identities = 68/328 (21%), Positives = 122/328 (37%), Gaps = 52/328 (16%)
Query 517 EGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL 576
+G R+ ++ + + + AG F++R+ + + L+ G P
Sbjct 630 KGKNRT-GTIVGVIVGVGLLSILAGVVMFTIRKR-RKRYTDDEELL---GMDVKPYIFTY 684
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
S+L + ++ + LG+G VY+G L
Sbjct 685 SEL---KSATQDFDPSNKLGEGGFGPVYKGNLNDGR------------------------ 717
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K+L F +S V H +L ++G C G ++V EY+ +G LD
Sbjct 718 -VVAVKLLSVGSRQGKGQFVAEIVAISSVLHRNLVKLYGCCFEGEHRMLVYEYLPNGSLD 776
Query 697 VWLRRERG-HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752
L ++ H+ + + + +A L YL + +VH +V NILL + +
Sbjct 777 QALFGDKTLHLDWSTRYEICLGVARGLVYLHEEASVRIVHRDVKASNILLDSRLVPQ--- 833
Query 753 PFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+SD G+ ++ + I +LAPE G L+ D + FG LE+
Sbjct 834 ----ISDFGLAKLYDDKKTHISTRVAGTIGYLAPEYAMRG--HLTEKTDVYAFGVVALEL 887
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
G EK++ + L E
Sbjct 888 VS-GRPNSDENLEEEKKYLLEWAWNLHE 914
>sp|P54645|AAPK1_RAT 5'-AMP-activated protein kinase catalytic
subunit alpha-1 OS=Rattus norvegicus OX=10116 GN=Prkaa1 PE=1
SV=2
Length=559
Score = 221 bits (564), Expect = 1e-60, Method: Composition-based stats.
Identities = 77/274 (28%), Positives = 111/274 (41%), Gaps = 30/274 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953
+ LG G FGKV + ++ TG VAVK L ++EI L+
Sbjct 26 HYILGDTLGVGTFGKVKVG----KHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKL 81
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012
H HIIK + + +VMEYV G L DY+ ++ + + QQI G+
Sbjct 82 FRHPHIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVD 139
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE
Sbjct 140 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 195
Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + D+WS GV LY LL V L + + G
Sbjct 196 ISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDH---------------VPTLFKKICDG 240
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P V L+K+ + + R T +++
Sbjct 241 IFYT-PQYLNPSVISLLKHMLQVDPMKRATIKDI 273
Score = 182 bits (463), Expect = 2e-47, Method: Composition-based stats.
Identities = 54/298 (18%), Positives = 94/298 (32%), Gaps = 39/298 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
Q RV LG GT V G+ + G
Sbjct 15 KQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGH----------------------- 51
Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+V +K+L+ D+ + H H+ ++ V + MV EYV G
Sbjct 52 -KVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGG 110
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L ++ + G + + QQ+ S + Y +VH ++ N+LL
Sbjct 111 ELFDYICKN-GRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD-------AHM 162
Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ E + APE + G + +D W G L +
Sbjct 163 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSSGVILYALLCG 221
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
P+ + P+ P + +L L +P +R + + I
Sbjct 222 TLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWF 279
>sp|Q968Y9|INSR_CAEEL Insulin-like receptor OS=Caenorhabditis
elegans OX=6239 GN=daf-2 PE=1 SV=2
Length=1846
Score = 232 bits (592), Expect = 1e-60, Method: Composition-based stats.
Identities = 94/319 (29%), Positives = 137/319 (43%), Gaps = 34/319 (11%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV- 927
L + + +D + + + GEG FGKV L + G+
Sbjct 1218 LSDFMQLNPEYCVDNKYNADDWELRQDDVVLGQQCGEGSFGKVYLGTGNNVVSLMGDRFG 1277
Query 928 --AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985
A+K D + E +I++ I+K G + +VME + LG+
Sbjct 1278 PCAIKINVDDPASTENLNYLMEANIMKNFKTNFIVKLYGVIS--TVQPAMVVMEMMDLGN 1335
Query 986 LRDYLPRHSIGL---------------AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030
LRDYL + +A QIC+GMAYL + + HRDLAARN +
Sbjct 1336 LRDYLRSKREDEVFNETDCNFFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCM 1395
Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
++ D VKIGDFG+A+ + H+YY+ PV W +PE LK+ KF SDVWSFGV
Sbjct 1396 INRDETVKIGDFGMARDLFY-HDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVV 1454
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
LYE++T + L I + + + P+ C Y +MK
Sbjct 1455 LYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKK-------------PECCENYWYKVMKM 1501
Query 1151 CWETEASFRPTFENLIPIL 1169
CW RPTF L+ +L
Sbjct 1502 CWRYSPRDRPTFLQLVHLL 1520
Score = 210 bits (534), Expect = 1e-53, Method: Composition-based stats.
Identities = 60/307 (20%), Positives = 110/307 (36%), Gaps = 47/307 (15%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
+ Q ++ G+G+ VY G + + DR +
Sbjct 1237 DDWELRQDDVVLGQQCGEGSFGKVYLGT---------------GNNVVSLMGDRFGPCAI 1281
Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+ V DP+ + L + A++M + ++GV ++V E ++ G L +L
Sbjct 1282 KINVDDPASTEN-LNYLMEANIMKNFKTNFIVKLYGVISTVQPAMVVMEMMDLGNLRDYL 1340
Query 700 RRERGH-------------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
R +R +P A Q+ ++YLE+ H ++ RN ++ R
Sbjct 1341 RSKREDEVFNETDCNFFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINR-- 1398
Query 747 LAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGF 800
+K+ D G+ + R+ + W++PE L G + D W F
Sbjct 1399 -----DETVKIGDFGMARDLFYHDYYKPSGKRMMPVRWMSPESLKDG--KFDSKSDVWSF 1451
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL---PEPSCPQLATLTSQCLTYEPTQRP 857
G L E+ G P S E ++ ++ PE + C Y P RP
Sbjct 1452 GVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRDRP 1511
Query 858 SFRTILR 864
+F ++
Sbjct 1512 TFLQLVH 1518
>sp|G5EFM9|NEKL3_CAEEL Serine/threonine-protein kinase nekl-3
OS=Caenorhabditis elegans OX=6239 GN=nekl-3 PE=1 SV=1
Length=302
Score = 213 bits (543), Expect = 1e-60, Method: Composition-based stats.
Identities = 60/288 (21%), Positives = 117/288 (41%), Gaps = 30/288 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHI 959
+G+G F +V + VA+K ++ + R +EID+L+ L H ++
Sbjct 28 KIGKGQFSEV----FRAQCTWVDLHVALKKIQVFEMVDQKARQDCLKEIDLLKQLNHVNV 83
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYL 1014
I+Y D + L +V+E G + + I + + Q+ +A++
Sbjct 84 IRYYASFIDNNQ--LNIVLELAEAGDMSRMIKHFKKGGRLIPEKTIWKYFVQLARALAHM 141
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H++ +HRD+ NV + + +VK+GD GL + ++ +PE ++
Sbjct 142 HSKRIMHRDIKPANVFITGNGIVKLGDLGLGRFFS---SKTTAAHSLVGTPYYMSPERIQ 198
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
E + + SD+WS G LYE+ +M + L + +E E
Sbjct 199 ESGYNFKSDLWSTGCLLYEMAALQSPFYG-------------DKMNLYSLCKKIENCEYP 245
Query 1135 PRPDKC-PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
P P ++ L+ C EAS RP ++ + + ++ +
Sbjct 246 PLPADIYSTQLRDLVSRCILPEASKRPETSEVLQVAEHMNNYFSPSGD 293
Score = 161 bits (408), Expect = 1e-42, Method: Composition-based stats.
Identities = 48/320 (15%), Positives = 105/320 (33%), Gaps = 47/320 (15%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
++ + +G+G + V+ + +L V L
Sbjct 16 DKLSLELFIIEKKIGKGQFSEVFRAQCTWV------------------------DLHVAL 51
Query 642 KVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
K + + L+ Q++H ++ + + + +V E E G +
Sbjct 52 KKIQVFEMVDQKARQDCLKEIDLLKQLNHVNVIRYYASFIDNNQLNIVLELAEAGDMSRM 111
Query 699 LRRERGH---VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
++ + +P QLA AL+++ +K ++H ++ N+ + + +
Sbjct 112 IKHFKKGGRLIPEKTIWKYFVQLARALAHMHSKRIMHRDIKPANVFIT-------GNGIV 164
Query 756 KLSDPGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
KL D G+G S+ V +++PE + + D W G L E+
Sbjct 165 KLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIQESGYNF--KSDLWSTGCLLYEMAALQ 222
Query 812 EAPLQSRSPS----EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ +K + + QL L S+C+ E ++RP +L+
Sbjct 223 SPFYGDKMNLYSLCKKIENCEYPPLPADIYSTQLRDLVSRCILPEASKRPETSEVLQVAE 282
Query 868 RLQPHNLADVLTVNPDSPAS 887
+ + S
Sbjct 283 HMNNYFSPSGDQSTTPSTQF 302
>sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapiens OX=9606
GN=LIMK2 PE=1 SV=1
Length=638
Score = 224 bits (570), Expect = 1e-60, Method: Composition-based stats.
Identities = 78/309 (25%), Positives = 131/309 (42%), Gaps = 38/309 (12%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
S + +F L LG+G FG+ T+ TG+++ +K L C + +
Sbjct 316 RCSSSYSQQIFRPCDLIHGEVLGKGFFGQ----AIKVTHKATGKVMVMKEL-IRCDEETQ 370
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQL 1000
+ E+ ++R+L H +++K+ G +K L L+ EY+ G+L+D+L Q
Sbjct 371 KTFLTEVKVMRSLDHPNVLKFIGVLYK--DKKLNLLTEYIEGGTLKDFLRSMDPFPWQQK 428
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY----- 1055
+ FA+ I GMAYLH+ IHRDL + N L+ D+ V + DFGL++ + E +
Sbjct 429 VRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKA 488
Query 1056 ------------RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
+ R +W APE L + D++SFG+ L E++ +
Sbjct 489 TTKKRTLRKNDRKKRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPD 548
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163
+ L+ G L + + P CP + L C E RP F
Sbjct 549 CLPRTLDF-----GLNVKLFWEKFV--------PTDCPPAFFPLAAICCRLEPESRPAFS 595
Query 1164 NLIPILKTV 1172
L + +
Sbjct 596 KLEDSFEAL 604
Score = 200 bits (509), Expect = 8e-53, Method: Composition-based stats.
Identities = 63/345 (18%), Positives = 111/345 (32%), Gaps = 62/345 (18%)
Query 553 PQPGETSNLIIMRGARASPRTLN-LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
P P ++ + +L S S ++ LG+G + +
Sbjct 294 PGPSSPKEPLLFSRDISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKAT 353
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
G +V+K L + F +M + H ++
Sbjct 354 GK------------------------VMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVL 389
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
GV + + ++TEY+E G L +LR P K+ A+ +AS ++YL + ++
Sbjct 390 KFIGVLYKDKKLNLLTEYIEGGTLKDFLR-SMDPFPWQQKVRFAKGIASGMAYLHSMCII 448
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------------------------GAL 767
H ++ N L+ + ++D G+
Sbjct 449 HRDLNSHNCLI-------KLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRK 501
Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--FDGEAPLQSRSPSEKEH 825
R V W+APE L G S +D + FG L EI + R+ +
Sbjct 502 KRYTVVGNPYWMAPEMLNG--KSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLN 559
Query 826 FY-QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ +P P L + C EP RP+F + L
Sbjct 560 VKLFWEKFVPTDCPPAFFPLAAICCRLEPESRPAFSKLEDSFEAL 604
>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic
subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4
Length=559
Score = 221 bits (564), Expect = 1e-60, Method: Composition-based stats.
Identities = 77/274 (28%), Positives = 111/274 (41%), Gaps = 30/274 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953
+ LG G FGKV + ++ TG VAVK L ++EI L+
Sbjct 26 HYILGDTLGVGTFGKVKVG----KHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKL 81
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012
H HIIK + + +VMEYV G L DY+ ++ + + QQI G+
Sbjct 82 FRHPHIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVD 139
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE
Sbjct 140 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 195
Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + D+WS GV LY LL V L + + G
Sbjct 196 ISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDH---------------VPTLFKKICDG 240
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P V L+K+ + + R T +++
Sbjct 241 IFYT-PQYLNPSVISLLKHMLQVDPMKRATIKDI 273
Score = 182 bits (463), Expect = 2e-47, Method: Composition-based stats.
Identities = 54/298 (18%), Positives = 94/298 (32%), Gaps = 39/298 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
Q RV LG GT V G+ + G
Sbjct 15 KQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGH----------------------- 51
Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+V +K+L+ D+ + H H+ ++ V + MV EYV G
Sbjct 52 -KVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGG 110
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L ++ + G + + QQ+ S + Y +VH ++ N+LL
Sbjct 111 ELFDYICKN-GRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD-------AHM 162
Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ E + APE + G + +D W G L +
Sbjct 163 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSSGVILYALLCG 221
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
P+ + P+ P + +L L +P +R + + I
Sbjct 222 TLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWF 279
>sp|O88866|HUNK_MOUSE Hormonally up-regulated neu tumor-associated
kinase OS=Mus musculus OX=10090 GN=Hunk PE=2 SV=1
Length=714
Score = 225 bits (574), Expect = 1e-60, Method: Composition-based stats.
Identities = 75/301 (25%), Positives = 122/301 (41%), Gaps = 25/301 (8%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--- 941
YL R LGEG F KV + + TGE VA+K + +
Sbjct 50 RDFQHHKRVGNYLIGSRKLGEGSFAKVR----EGLHVLTGEKVAIKVIDKKRAKKDTYVT 105
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQL 1000
++E I + + H +I + E E S LVME P G+L + + + A+
Sbjct 106 KNLRREGQIQQMIRHPNITQLLDILE--TENSYYLVMELCPGGNLMHKIYEKKRLDEAEA 163
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+ +Q+ + +LH +HRDL N+LLD D +K+ DFGL+
Sbjct 164 RRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQ 223
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
SP + APE L K+ DVWS GV +Y +LT P L
Sbjct 224 CGSPA-YAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALY-------- 274
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180
+++++ P P + + +++ E + RP + + + ++E Y G+
Sbjct 275 ----QKMVDKAMN-PLPTQLSTGAVNFLRSLLEPDPVKRPNIQQALAN-RWLNENYTGKV 328
Query 1181 P 1181
P
Sbjct 329 P 329
Score = 164 bits (414), Expect = 2e-40, Method: Composition-based stats.
Identities = 59/344 (17%), Positives = 105/344 (31%), Gaps = 49/344 (14%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L H+ + LG+G+ V EG + G
Sbjct 49 LRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGE---------------------- 86
Query 636 ELRVVLKVLDPSHHD----IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+V +KV+D + + + H ++ + + +V E
Sbjct 87 --KVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCP 144
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G L + E+ + A +QL SA+ +L +VH ++ N+LL
Sbjct 145 GGNLMHKIY-EKKRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDN----- 198
Query 752 SPFIKLSDPGV----GLGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
IKL D G+ G+ S + + APE L +D W G +
Sbjct 199 --NIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA--RKKYGPKIDVWSIGVNMY 254
Query 806 EICFDGEAPL----QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861
+ G P S ++ + + LP L +P +RP+ +
Sbjct 255 AML-TGTLPFTVEPFSLRALYQKMVDKAMNPLPTQLSTGAVNFLRSLLEPDPVKRPNIQQ 313
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
L + + + V + S + L LG
Sbjct 314 ALANRWLNENYTGKVPCNVTYPNRISLEDLSPSVVLHMTEKLGY 357
>sp|Q9IA88|SIK2_CHICK Serine/threonine-protein kinase SIK2 OS=Gallus
gallus OX=9031 GN=SIK2 PE=2 SV=1
Length=798
Score = 227 bits (578), Expect = 1e-60, Method: Composition-based stats.
Identities = 67/273 (25%), Positives = 110/273 (40%), Gaps = 29/273 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTL 954
+ R LG+G+F V L + T VA+K + K P + +E+ I++ L
Sbjct 25 FYDIERTLGKGNFAVVKL----ARHRVTKTQVAIKIIDKTRLDPSNLEKIYREVQIMKLL 80
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAY 1013
H HIIK E + L +V E+ G + D+L + + ++ QI + Y
Sbjct 81 NHPHIIKLYQVMETKD--MLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEY 138
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
H+ H +HRDL N+LLD + +K+ DFG G + SP + APE
Sbjct 139 CHSHHIVHRDLKTENLLLDANMNIKLADFGFGNFYKSGEP---LSTWCGSPP-YAAPEVF 194
Query 1074 KEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ ++ D+WS GV LY L+ P + L + + G
Sbjct 195 EGKEYEGPHLDIWSLGVVLYVLVCGSLPFDGP---------------NLPTLRQRVLEG- 238
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
R P + L++ + + R T +
Sbjct 239 RFRIPYFMSEDCETLIRRMLVVDPTKRITISQI 271
Score = 201 bits (512), Expect = 3e-52, Method: Composition-based stats.
Identities = 65/350 (19%), Positives = 122/350 (35%), Gaps = 40/350 (11%)
Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
+++ AS + +Q RV +I LG+G V R RV
Sbjct 1 MVIMSEDASVPAPSAAQPRPLRVGFYDIE--RTLGKGNFAVVKLARHRV----------- 47
Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVR 679
+ +V +K++D + D + Y +M ++H H+ ++ V
Sbjct 48 -------------TKTQVAIKIIDKTRLDPSNLEKIYREVQIMKLLNHPHIIKLYQVMET 94
Query 680 GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRN 739
+VTE+ ++G + L GH+ + Q+ SA+ Y + ++VH ++ N
Sbjct 95 KDMLYIVTEFAKNGEMFDHLTSN-GHLSESEARKKFWQILSAVEYCHSHHIVHRDLKTEN 153
Query 740 ILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAMD 796
+LL + IKL+D G G P+ APE G +D
Sbjct 154 LLLD-------ANMNIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYE-GPHLD 205
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
W G L + P+ ++ + + R+P TL + L +PT+R
Sbjct 206 IWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFMSEDCETLIRRMLVVDPTKR 265
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906
+ I + +L +++ + + G
Sbjct 266 ITISQIKQHKWMQADPSLRQQQSLSFSMQNYNSNLGDYNEQVLGIMQTLG 315
>sp|Q8AXB4|PAK3_XENLA Serine/threonine-protein kinase PAK 3 OS=Xenopus
laevis OX=8355 GN=pak3 PE=2 SV=1
Length=564
Score = 221 bits (564), Expect = 1e-60, Method: Composition-based stats.
Identities = 70/330 (21%), Positives = 124/330 (38%), Gaps = 26/330 (8%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
S T+ R+ R + + + + K+ + +G+G G V
Sbjct 245 NSNSSTSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV-- 302
Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
Y + TG+ VA+K + P+ + EI ++R + +I+ Y E
Sbjct 303 --YTAIDIATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE-- 357
Query 974 LQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033
L +VMEY+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+LL
Sbjct 358 LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGM 417
Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
D VK+ DFG + R +W APE + + D+WS G+ E
Sbjct 418 DGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIE 474
Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
++ PP + T L P++ + C E
Sbjct 475 MV-----EGEPPYLNENPLRALYLIATNGT--------PELQNPERLSAIFRDFLNRCLE 521
Query 1154 TEASFRPTFENLI--PILKTVHEKYQGQAP 1181
+ R + + L+ P LK + + P
Sbjct 522 MDVDRRGSAKELLQHPFLK-IAKPLSSLTP 550
Score = 183 bits (464), Expect = 1e-47, Method: Composition-based stats.
Identities = 63/340 (19%), Positives = 111/340 (33%), Gaps = 57/340 (17%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV------------DQKEITQLSHL 595
PQP E SN R + R S+++ + +K+ T+ +
Sbjct 236 TSPVTPQP-ENSNSSTSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKI 294
Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655
GQG VY D V +K ++
Sbjct 295 GQGASGTVY------------------------TAIDIATGQEVAIKQMNLQQQPKKELI 330
Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715
+M + + ++ + G E +V EY+ G L + + V
Sbjct 331 INEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TETCMDEGQIAAVC 388
Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREE 771
++ AL +L + ++H ++ NILL G +KL+D G R
Sbjct 389 RECLQALDFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCAQITPEQSKRST 441
Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
V W+APE + A +D W G +E+ +GE P + +P +
Sbjct 442 MVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNG 498
Query 832 RL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
PE ++CL + +R S + +L+
Sbjct 499 TPELQNPERLSAIFRDFLNRCLEMDVDRRGSAKELLQHPF 538
>sp|C0LGW2|PAM74_ARATH Probable LRR receptor-like serine/threonine-protein
kinase PAM74 OS=Arabidopsis thaliana OX=3702 GN=PAM74
PE=1 SV=1
Length=884
Score = 228 bits (581), Expect = 1e-60, Method: Composition-based stats.
Identities = 67/254 (26%), Positives = 115/254 (45%), Gaps = 12/254 (5%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
E VAVK L Q +K E+D+L ++H +++ G C+++ L L+ E++P G
Sbjct 602 EQVAVKVLSQSSS-QGYKHFKAEVDLLLRVHHTNLVSLVGYCDERDH--LALIYEFLPKG 658
Query 985 SLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLV 1037
LR +L S I L A + G+ YLH+ +HRD+ N+LLD
Sbjct 659 DLRQHLSGKSGGSFINWGNRLRIALEAALGLEYLHSGCTPPIVHRDIKTTNILLDEQLKA 718
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
K+ DFGL+++ P G E + +P + PE + + SDV+SFG+ L E++T+
Sbjct 719 KLADFGLSRSFPIGGETHISTVVAGTP-GYLDPEYYQTTRLGEKSDVYSFGIVLLEIITN 777
Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157
+K + ++T +T++++ + V L +C +
Sbjct 778 QPVIDQSRSK-SHISQWVGFELTRGDITKIMDPNLNGDYESRSVWRVLELAMSCANPSSV 836
Query 1158 FRPTFENLIPILKT 1171
RP + LK
Sbjct 837 NRPNMSQVANELKE 850
Score = 192 bits (488), Expect = 6e-49, Method: Composition-based stats.
Identities = 58/251 (23%), Positives = 89/251 (35%), Gaps = 35/251 (14%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +KVL S F L+ +V HT+L + G C ++ E++ G L
Sbjct 603 QVAVKVLSQSSSQGYKHFKAEVDLLLRVHHTNLVSLVGYCDERDHLALIYEFLPKGDLRQ 662
Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTS 752
L + G + W ++ +A + A L YL + +VH ++ NILL A
Sbjct 663 HLSGKSGGSFINWGNRLRIALEAALGLEYLHSGCTPPIVHRDIKTTNILLDEQLKA---- 718
Query 753 PFIKLSDPGVGLG------ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
KL+D G+ +L PE L D + FG LLE
Sbjct 719 ---KLADFGLSRSFPIGGETHISTVVAGTPGYLDPEYYQT--TRLGEKSDVYSFGIVLLE 773
Query 807 ICFDGEAPLQSRS---PSEKEHFYQRQHRLPEPSCPQLA------------TLTSQCLTY 851
I + QSRS S+ F + + + P L L C
Sbjct 774 IITNQPVIDQSRSKSHISQWVGFELTRGDITKIMDPNLNGDYESRSVWRVLELAMSCANP 833
Query 852 EPTQRPSFRTI 862
RP+ +
Sbjct 834 SSVNRPNMSQV 844
>sp|Q6CVA2|STE20_KLULA Serine/threonine-protein kinase STE20 OS=Kluyveromyces
lactis (strain ATCC 8585 / CBS 2359 / DSM 70799
/ NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=STE20 PE=3
SV=1
Length=989
Score = 229 bits (585), Expect = 1e-60, Method: Composition-based stats.
Identities = 65/282 (23%), Positives = 121/282 (43%), Gaps = 25/282 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G G V Y GT VA+K + + P+ + EI +++ H +I+
Sbjct 703 KIGQGASGGV----YTAYELGTNASVAIKQMNLEKQPK-KELIVNEILVMKGSKHNNIVN 757
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
+ +G+ L +VMEY+ GSL D + + Q+ +++ +G+ +LH++ IH
Sbjct 758 FIDSYLFRGD--LWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIH 815
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RD+ + N+LL + +K+ DFG + +E R +W APE + ++
Sbjct 816 RDIKSDNILLSMNGDIKLTDFGFCAQI---NEVNLKRTTMVGTPYWMAPEVVSRKEYGPK 872
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
D+WS G+ + E++ + T L IA +L P
Sbjct 873 VDIWSLGIMIIEMI-EGEPPYLNETPLRALYLIATNGTP------------KLKDPGNLS 919
Query 1142 CEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAP 1181
++ + C + R T +L+ P + + E+ AP
Sbjct 920 HKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAP 961
Score = 181 bits (458), Expect = 5e-45, Method: Composition-based stats.
Identities = 51/271 (19%), Positives = 91/271 (34%), Gaps = 44/271 (16%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
+GQG VY + G V +K ++
Sbjct 703 KIGQGASGGVY------------------------TAYELGTNASVAIKQMNLEKQPKKE 738
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
+M H ++ + + +V EY+E G L + +
Sbjct 739 LIVNEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTH--CILTEGQIGA 796
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSR 769
V+++ L +L +K ++H ++ NILL+ + IKL+D G L R
Sbjct 797 VSRETLKGLQFLHSKGVIHRDIKSDNILLS-------MNGDIKLTDFGFCAQINEVNLKR 849
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
V W+APE + +D W G ++E+ +GE P + +P +
Sbjct 850 TTMVGTPYWMAPEVVS--RKEYGPKVDIWSLGIMIIEMI-EGEPPYLNETPLRALYLIAT 906
Query 830 QHRL----PEPSCPQLATLTSQCLTYEPTQR 856
P ++A + CL +P R
Sbjct 907 NGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR 937
>sp|Q14012|KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase
type 1 OS=Homo sapiens OX=9606 GN=CAMK1 PE=1 SV=1
Length=370
Score = 216 bits (549), Expect = 1e-60, Method: Composition-based stats.
Identities = 66/289 (23%), Positives = 101/289 (35%), Gaps = 30/289 (10%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
P + LG G F +V L + T ++VA+K + +
Sbjct 8 PRWKQAEDIRDIYDFRDVLGTGAFSEVIL----AEDKRTQKLVAIKCIAKEALEGKEGSM 63
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLF 1003
+ EI +L + H +I+ E G L L+M+ V G L D +
Sbjct 64 ENEIAVLHKIKHPNIVALDDIYESGGH--LYLIMQLVSGGELFDRIVEKGFYTERDASRL 121
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVL---LDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
Q+ + + YLH +HRDL N+L LD D + I DFGL+K G V
Sbjct 122 IFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPG----SVLST 177
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
+ APE L + + A D WS GV Y LL +
Sbjct 178 ACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPF--------------YDEND 223
Query 1121 VLRLTELLERGERLPRP--DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
++L+ P D +++ E + R T E +
Sbjct 224 AKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQ 272
Score = 150 bits (378), Expect = 6e-38, Method: Composition-based stats.
Identities = 41/284 (14%), Positives = 87/284 (31%), Gaps = 41/284 (14%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
LG G + V + D+ + V +K + +
Sbjct 24 DVLGTGAFSEV------------------------ILAEDKRTQKLVAIKCIAKEALEGK 59
Query 653 L-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711
+ +++ ++ H ++ + + G ++ + V G L + E+G
Sbjct 60 EGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRI-VEKGFYTERDA 118
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-- 769
+ Q+ A+ YL + +VH ++ N+L + I +SD G+
Sbjct 119 SRLIFQVLDAVKYLHDLGIVHRDLKPENLL----YYSLDEDSKIMISDFGLSKMEDPGSV 174
Query 770 -EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
++APE L S A+D W G I G P + ++
Sbjct 175 LSTACGTPGYVAPEVLAQ--KPYSKAVDCWSIGVIAY-ILLCGYPPFYDENDAKLFEQIL 231
Query 829 R-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ + + +P +R + L+
Sbjct 232 KAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPW 275
>sp|Q63450|KCC1A_RAT Calcium/calmodulin-dependent protein kinase
type 1 OS=Rattus norvegicus OX=10116 GN=Camk1 PE=1 SV=2
Length=374
Score = 216 bits (549), Expect = 1e-60, Method: Composition-based stats.
Identities = 66/296 (22%), Positives = 102/296 (34%), Gaps = 30/296 (10%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ + P + LG G F +V L + T ++VA+K +
Sbjct 1 MPGAVEGPRWKQAEDIRDIYDFRDVLGTGAFSEVIL----AEDKRTQKLVAIKCIAKKAL 56
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-G 996
+ EI +L + H +I+ E G L L+M+ V G L D +
Sbjct 57 EGKEGSMENEIAVLHKIKHPNIVALDDIYESGGH--LYLIMQLVSGGELFDRIVEKGFYT 114
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL---LDNDRLVKIGDFGLAKAVPEGHE 1053
Q+ + + YLH +HRDL N+L LD D + I DFGL+K G
Sbjct 115 ERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPG-- 172
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
V + APE L + + A D WS GV Y LL
Sbjct 173 --SVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPF------------ 218
Query 1114 IAQGQMTVLRLTELLERGERLPRP--DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ ++L+ P D +++ E + R T E +
Sbjct 219 --YDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQ 272
Score = 150 bits (378), Expect = 5e-38, Method: Composition-based stats.
Identities = 41/284 (14%), Positives = 87/284 (31%), Gaps = 41/284 (14%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
LG G + V + D+ + V +K + +
Sbjct 24 DVLGTGAFSEV------------------------ILAEDKRTQKLVAIKCIAKKALEGK 59
Query 653 L-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711
+ +++ ++ H ++ + + G ++ + V G L + E+G
Sbjct 60 EGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRI-VEKGFYTERDA 118
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-- 769
+ Q+ A+ YL + +VH ++ N+L + I +SD G+
Sbjct 119 SRLIFQVLDAVKYLHDLGIVHRDLKPENLL----YYSLDEDSKIMISDFGLSKMEDPGSV 174
Query 770 -EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
++APE L S A+D W G I G P + ++
Sbjct 175 LSTACGTPGYVAPEVLAQ--KPYSKAVDCWSIGVIAY-ILLCGYPPFYDENDAKLFEQIL 231
Query 829 R-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ + + +P +R + L+
Sbjct 232 KAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPW 275
>sp|Q91YS8|KCC1A_MOUSE Calcium/calmodulin-dependent protein kinase
type 1 OS=Mus musculus OX=10090 GN=Camk1 PE=1 SV=1
Length=374
Score = 216 bits (549), Expect = 1e-60, Method: Composition-based stats.
Identities = 66/296 (22%), Positives = 102/296 (34%), Gaps = 30/296 (10%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ + P + LG G F +V L + T ++VA+K +
Sbjct 1 MPGAVEGPRWKQAEDIRDIYDFRDVLGTGAFSEVIL----AEDKRTQKLVAIKCIAKKAL 56
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-G 996
+ EI +L + H +I+ E G L L+M+ V G L D +
Sbjct 57 EGKEGSMENEIAVLHKIKHPNIVALDDIYESGGH--LYLIMQLVSGGELFDRIVEKGFYT 114
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL---LDNDRLVKIGDFGLAKAVPEGHE 1053
Q+ + + YLH +HRDL N+L LD D + I DFGL+K G
Sbjct 115 ERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPG-- 172
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
V + APE L + + A D WS GV Y LL
Sbjct 173 --SVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPF------------ 218
Query 1114 IAQGQMTVLRLTELLERGERLPRP--DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ ++L+ P D +++ E + R T E +
Sbjct 219 --YDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQ 272
Score = 150 bits (378), Expect = 5e-38, Method: Composition-based stats.
Identities = 41/284 (14%), Positives = 87/284 (31%), Gaps = 41/284 (14%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
LG G + V + D+ + V +K + +
Sbjct 24 DVLGTGAFSEV------------------------ILAEDKRTQKLVAIKCIAKKALEGK 59
Query 653 L-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711
+ +++ ++ H ++ + + G ++ + V G L + E+G
Sbjct 60 EGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRI-VEKGFYTERDA 118
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-- 769
+ Q+ A+ YL + +VH ++ N+L + I +SD G+
Sbjct 119 SRLIFQVLDAVKYLHDLGIVHRDLKPENLL----YYSLDEDSKIMISDFGLSKMEDPGSV 174
Query 770 -EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
++APE L S A+D W G I G P + ++
Sbjct 175 LSTACGTPGYVAPEVLAQ--KPYSKAVDCWSIGVIAY-ILLCGYPPFYDENDAKLFEQIL 231
Query 829 R-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ + + +P +R + L+
Sbjct 232 KAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPW 275
>sp|O19004|ARAF_PIG Serine/threonine-protein kinase A-Raf OS=Sus
scrofa OX=9823 GN=ARAF PE=2 SV=1
Length=606
Score = 223 bits (567), Expect = 1e-60, Method: Composition-based stats.
Identities = 75/326 (23%), Positives = 133/326 (41%), Gaps = 27/326 (8%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
+ P ++ R + + + ++ ++ +G G FG V
Sbjct 268 KSPHSKSPSEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 327
Query 915 CYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
+ VAVK LK A + +K E+ +LR H +I+ + G G
Sbjct 328 RWHG-------DVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG--- 377
Query 974 LQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031
++ ++ SL +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L
Sbjct 378 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 437
Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFG 1088
VKIGDFGLA V + E V W A E ++ + + SDV+++G
Sbjct 438 HEGLTVKIGDFGLA-TVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYG 496
Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148
V LYEL+T ++ + + +G ++ CP + L+
Sbjct 497 VVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSK----------ISSNCPKAMRRLL 546
Query 1149 KNCWETEASFRPTFENLIPILKTVHE 1174
+C + + RP F ++ ++ +
Sbjct 547 SDCLKFQREERPLFPQILATIELLQR 572
Score = 207 bits (528), Expect = 2e-55, Method: Composition-based stats.
Identities = 71/366 (19%), Positives = 122/366 (33%), Gaps = 53/366 (14%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQL-SFHRVDQKEITQLSHLGQGTRTNVYEG 606
+ P E + + + L + V E+ L +G G+ V+ G
Sbjct 268 KSPHSKSPSEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 327
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH--HDIALAFYETASLMSQ 664
R + V +KVL + + A AF ++ +
Sbjct 328 RWHGD---------------------------VAVKVLKVAQPTAEQAQAFKNEMQVLRK 360
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
H ++ G R ++T++ E L L M + VA+Q A + Y
Sbjct 361 TRHVNILLFMGFMTRPG-FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDY 419
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778
L KN++H ++ NI L +K+ D G+ GA E+ + W
Sbjct 420 LHAKNIIHRDLKSNNIFLHEGL-------TVKIGDFGLATVKTRWSGAQPLEQPSGSVLW 472
Query 779 LAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP- 836
+A E + N S D + +G L E+ G P ++ F + L
Sbjct 473 MAAEVIRMQDPNPYSFQSDVYAYGVVLYELM-TGSLPYSHIGSRDQIIFMVGRGYLSPDL 531
Query 837 -----SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
+CP+ + L S CL ++ +RP F IL + LQ + + S
Sbjct 532 SKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQA 591
Query 891 VFHKRY 896
Sbjct 592 DELPAC 597
>sp|Q6R2K3|SRF3_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 3 OS=Arabidopsis
thaliana OX=3702 GN=SRF3 PE=1 SV=1
Length=776
Score = 226 bits (576), Expect = 1e-60, Method: Composition-based stats.
Identities = 71/334 (21%), Positives = 134/334 (40%), Gaps = 21/334 (6%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
I+ ++ + + + + + + +G G G V
Sbjct 450 IISPERPVKKTSPKRLPLTSVKHYSIASLQQYTESFAQENLIGSGMLGSVYRARL----- 504
Query 922 GTGEMVAVKALKADCGPQHRS-GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
G++ AVK L Q + + + ++ + + H +I++ G C + ++ LV EY
Sbjct 505 PNGKLFAVKKLDKRASEQQQDHEFIELVNNIDMIRHSNIVELVGYCAEHDQR--LLVYEY 562
Query 981 VPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLD 1032
G+L+D L + + + A + YLH IHR+ + NVLLD
Sbjct 563 CSNGTLQDGLHSDDEFKKKLSWNTRVSMALGAARALEYLHEVCEPPIIHRNFKSANVLLD 622
Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092
+D V + D GLA + G ++ + + APE + + SDV+SFGV +
Sbjct 623 DDLSVLVSDCGLAPLISSG-SVSQLSGQLLAAYGYGAPE-FDSGIYTWQSDVYSFGVVML 680
Query 1093 ELLTHCDSSQSPPTKFLE-LIGIAQGQM-TVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
ELLT S ++ + L+ A Q+ + L ++++ P K ++
Sbjct 681 ELLTGRMSYDRDRSRGEQFLVRWAIPQLHDIDALGKMVDPSLNGQYPAKSLSHFADIISR 740
Query 1151 CWETEASFRPTFENLIP-ILKTVHEKYQGQAPSV 1183
C ++E FRP ++ +L + + G S
Sbjct 741 CVQSEPEFRPLMSEVVQDLLDMIRRERHGSGDST 774
Score = 177 bits (448), Expect = 2e-44, Method: Composition-based stats.
Identities = 62/346 (18%), Positives = 116/346 (34%), Gaps = 72/346 (21%)
Query 567 ARASPRTLNLSQLSFHRVD-----QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
+ SP+ L L+ + + + + Q + +G G +VY RL
Sbjct 458 KKTSPKRLPLTSVKHYSIASLQQYTESFAQENLIGSGMLGSVYRARLPNGKLF------- 510
Query 622 DDEDPLVPGRDRGQELRVVLKVLDP--SHHDIALAFYETASLMSQVSHTHLAFVHGVCVR 679
+K LD S F E + + + H+++ + G C
Sbjct 511 ------------------AVKKLDKRASEQQQDHEFIELVNNIDMIRHSNIVELVGYCAE 552
Query 680 GPENIMVTEYVEHGPLDVWLRRE---RGHVPMAWKMVVAQQLASALSYLE---NKNLVHG 733
+ ++V EY +G L L + + + ++ +A A AL YL ++H
Sbjct 553 HDQRLLVYEYCSNGTLQDGLHSDDEFKKKLSWNTRVSMALGAARALEYLHEVCEPPIIHR 612
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGG 787
N N+LL + +SD G+ S + + + APE
Sbjct 613 NFKSANVLLD-------DDLSVLVSDCGLAPLISSGSVSQLSGQLLAAYGYGAPE---FD 662
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS---------- 837
+ + D + FG +LE+ + + RS E+ +L +
Sbjct 663 SGIYTWQSDVYSFGVVMLELLTGRMSYDRDRSRGEQFLVRWAIPQLHDIDALGKMVDPSL 722
Query 838 --------CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
A + S+C+ EP RP +++DL +
Sbjct 723 NGQYPAKSLSHFADIISRCVQSEPEFRPLMSEVVQDLLDMIRRERH 768
>sp|Q6XHB2|ROCO4_DICDI Probable serine/threonine-protein kinase
roco4 OS=Dictyostelium discoideum OX=44689 GN=roco4 PE=1 SV=1
Length=1726
Score = 232 bits (591), Expect = 1e-60, Method: Composition-based stats.
Identities = 76/355 (21%), Positives = 133/355 (37%), Gaps = 54/355 (15%)
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY----------- 896
C+ P P + ++ LQ +P P +
Sbjct 966 CVQKNPRADPYYFDFSSCISALQDGKPHLFCRNDPSIPVRIDYIAPDLCLKKVPTLADNE 1025
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS------GWKQEIDI 950
++ + +G+G FG V + +VA+K+L +++E+ I
Sbjct 1026 IEYEKQIGKGGFGLV----HKGRLVKDKSVVAIKSLILGDSEGETEMIEKFQEFQREVFI 1081
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQIC 1008
+ L H +I+K G + +VME+VP G L L H I + L I
Sbjct 1082 MSNLNHPNIVKLYGLMHNPPR----MVMEFVPCGDLYHRLLDKAHPIKWSVKLRLMLDIA 1137
Query 1009 EGMAYLHAQH--YIHRDLAARNVLL---DNDRLV--KIGDFGLAKAVPEGHEYYRVREDG 1061
G+ Y+ Q+ +HRDL + N+ L D + V K+ DFGL+ +
Sbjct 1138 LGIEYMQNQNPPIVHRDLRSPNIFLQSLDENAPVCAKVADFGLS------QQSVHSVSGL 1191
Query 1062 DSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
W APE + +E + +D +SF + LY +LT ++ I + +
Sbjct 1192 LGNFQWMAPETIGAEEESYTEKADTYSFAMILYTILTGEGPFDEYSYGKIKFINMIR--- 1248
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
E G R P+ CP + ++++ CW + RP F ++ L +
Sbjct 1249 ---------EEGLRPTIPEDCPPRLRNVIELCWSGDPKKRPHFSYIVKELSELRN 1294
Score = 223 bits (568), Expect = 8e-58, Method: Composition-based stats.
Identities = 74/359 (21%), Positives = 127/359 (35%), Gaps = 48/359 (13%)
Query 532 ALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPR-TLNLSQLSFHRVDQ---K 587
RA F C +L R L +V
Sbjct 965 HCVQKNPRADPYYFDFSSCISALQDGKPHLFCRNDPSIPVRIDYIAPDLCLKKVPTLADN 1024
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
EI +G+G V++GRL + S V +K L
Sbjct 1025 EIEYEKQIGKGGFGLVHKGRLVKDKS------------------------VVAIKSLILG 1060
Query 648 HHDIA-------LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
+ F +MS ++H ++ ++G+ P MV E+V G L L
Sbjct 1061 DSEGETEMIEKFQEFQREVFIMSNLNHPNIVKLYGLMHNPPR--MVMEFVPCGDLYHRLL 1118
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ + + K+ + +A + Y++N+N +VH ++ NI L L E K++
Sbjct 1119 DKAHPIKWSVKLRLMLDIALGIEYMQNQNPPIVHRDLRSPNIFL--QSLDENAPVCAKVA 1176
Query 759 DPGVG-LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
D G+ S + W+APE + S + D + F L I GE P
Sbjct 1177 DFGLSQQSVHSVSGLLGNFQWMAPETIGAEEESYTEKADTYSFAMILYTIL-TGEGPFDE 1235
Query 818 RSPSEKEHFYQR-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
S + + + +PE P+L + C + +P +RP F I+++L+ L+
Sbjct 1236 YSYGKIKFINMIREEGLRPTIPEDCPPRLRNVIELCWSGDPKKRPHFSYIVKELSELRN 1294
>sp|Q62829|PAK3_RAT Serine/threonine-protein kinase PAK 3 OS=Rattus
norvegicus OX=10116 GN=Pak3 PE=1 SV=1
Length=544
Score = 221 bits (562), Expect = 1e-60, Method: Composition-based stats.
Identities = 66/318 (21%), Positives = 120/318 (38%), Gaps = 23/318 (7%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
T + + T+ R+ R + + + + K+ + +G+G G
Sbjct 221 TPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASG 280
Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
V Y + TG+ VA+K + P+ + EI ++R + +I+ Y
Sbjct 281 TV----YTALDIATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVG 335
Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029
E L +VMEY+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+
Sbjct 336 DE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNI 393
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
LL D VK+ DFG + R +W APE + + D+WS G+
Sbjct 394 LLGMDGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGI 450
Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149
E++ PP + T L P++ +
Sbjct 451 MAIEMV-----EGEPPYLNENPLRALYLIATNGT--------PELQNPERLSAVFRDFLN 497
Query 1150 NCWETEASFRPTFENLIP 1167
C E + R + + L+
Sbjct 498 RCLEMDVDRRGSAKELLQ 515
Score = 178 bits (451), Expect = 4e-46, Method: Composition-based stats.
Identities = 54/291 (19%), Positives = 97/291 (33%), Gaps = 44/291 (15%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+K+ T+ +GQG VY D V +K +
Sbjct 264 PKKKYTRFEKIGQGASGTVY------------------------TALDIATGQEVAIKQM 299
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ +M + + ++ + G E +V EY+ G L +
Sbjct 300 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 357
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ V ++ AL +L + ++H ++ NILL G +KL+D G
Sbjct 358 CMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 410
Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
R V W+APE + A +D W G +E+ +GE P + +P
Sbjct 411 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENP 467
Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ PE ++CL + +R S + +L+
Sbjct 468 LRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPF 518
>sp|Q39193|SRK2I_ARATH Serine/threonine-protein kinase SRK2I OS=Arabidopsis
thaliana OX=3702 GN=SRK2I PE=1 SV=1
Length=361
Score = 215 bits (547), Expect = 1e-60, Method: Composition-based stats.
Identities = 69/282 (24%), Positives = 119/282 (42%), Gaps = 26/282 (9%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947
P + ++D+G G+FG L + T E+VAVK + + G + ++E
Sbjct 13 MPIMHDSDRYDFVKDIGSGNFGVARLM----RDKLTKELVAVKYI--ERGDKIDENVQRE 66
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQ 1006
I R+L H +I+++K L ++MEY G L + + + F QQ
Sbjct 67 IINHRSLRHPNIVRFKEVILTPTH--LAIIMEYASGGELYERICNAGRFSEDEARFFFQQ 124
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+ G++Y H+ HRDL N LLD +KI DFG +K + + + +P
Sbjct 125 LLSGVSYCHSMQICHRDLKLENTLLDGSPAPRLKICDFGYSK---SSVLHSQPKSTVGTP 181
Query 1065 VFWYAPECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
+ APE L ++ +DVWS GVTLY +L + P + +
Sbjct 182 A-YIAPEVLLRQEYDGKIADVWSCGVTLYVMLVGAYPFEDPE----------EPRDYRKT 230
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ +L +P + E HL+ + + + R + +
Sbjct 231 IQRILSVKYSIPDDIRISPECCHLISRIFVADPATRISIPEI 272
Score = 161 bits (408), Expect = 5e-42, Method: Composition-based stats.
Identities = 54/329 (16%), Positives = 97/329 (29%), Gaps = 41/329 (12%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
D + +G G RD+ + V +K +
Sbjct 18 DSDRYDFVKDIGSGNFG------------------------VARLMRDKLTKELVAVKYI 53
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ I + H ++ V + ++ EY G L + G
Sbjct 54 ERGDK-IDENVQREIINHRSLRHPNIVRFKEVILTPTHLAIIMEYASGGELYERI-CNAG 111
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
QQL S +SY + + H ++ N LL +P +K+ D G
Sbjct 112 RFSEDEARFFFQQLLSGVSYCHSMQICHRDLKLENTLLD-----GSPAPRLKICDFGYSK 166
Query 765 GAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
++ + V ++APE L D W G TL + P
Sbjct 167 SSVLHSQPKSTVGTPAYIAPEVLLRQEYD-GKIADVWSCGVTLYVMLVGAYPFEDPEEPR 225
Query 822 EKEHFYQR----QHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ QR ++ +P+ P+ L S+ +P R S I L+
Sbjct 226 DYRKTIQRILSVKYSIPDDIRISPECCHLISRIFVADPATRISIPEIKTHSWFLKNLPAD 285
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
+ N S +P + ++ +
Sbjct 286 LMNESNTGSQFQEPEQPMQSLDTIMQIIS 314
>sp|Q9FYK0|TMK2_ARATH Receptor-like kinase TMK2 OS=Arabidopsis
thaliana OX=3702 GN=TMK2 PE=1 SV=1
Length=886
Score = 228 bits (581), Expect = 1e-60, Method: Composition-based stats.
Identities = 71/281 (25%), Positives = 116/281 (41%), Gaps = 22/281 (8%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRT 953
+ LG G FG V G +AVK +++ + +K EI +L
Sbjct 545 YNFDEKNILGRGGFGIVYKGEL-----HDGTKIAVKRMESSIISGKGLDEFKSEIAVLTR 599
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------RHSIGLAQLLLFAQQI 1007
+ H +++ G C + E+ LV +Y+P G+L ++ + + L+ A +
Sbjct 600 VRHRNLVVLHGYCLEGNER--LLVYQYMPQGTLSRHIFYWKEEGLRPLEWTRRLIIALDV 657
Query 1008 CEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
G+ YLH Q +IHRDL N+LL +D K+ DFGL + PEG + + G
Sbjct 658 ARGVEYLHTLAHQSFIHRDLKPSNILLGDDMHAKVADFGLVRLAPEGTQSIETKIAG--T 715
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+ APE + DV+SFGV L ELLT + ++ + +M + +
Sbjct 716 FGYLAPEYAVTGRVTTKVDVYSFGVILMELLTGRKALDVARSEEEVHLATWFRRMFINKG 775
Query 1125 TELLERGERLPRPDKCPCE---VYHLMKNCWETEASFRPTF 1162
+ E + ++ V L C E RP
Sbjct 776 SFPKAIDEAMEVNEETLRSINIVAELANQCSSREPRDRPDM 816
Score = 217 bits (552), Expect = 6e-57, Method: Composition-based stats.
Identities = 67/312 (21%), Positives = 125/312 (40%), Gaps = 67/312 (21%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
R + + LG+G VY+G L ++ +K
Sbjct 541 RDATYNFDEKNILGRGGFGIVYKGELHDG-------------------------TKIAVK 575
Query 643 VLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
++ S F +++++V H +L +HG C+ G E ++V +Y+ G L +
Sbjct 576 RMESSIISGKGLDEFKSEIAVLTRVRHRNLVVLHGYCLEGNERLLVYQYMPQGTLSRHIF 635
Query 701 --RERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSP 753
+E G P+ W ++++A +A + YL +++ +H ++ NILL G
Sbjct 636 YWKEEGLRPLEWTRRLIIALDVARGVEYLHTLAHQSFIHRDLKPSNILL-------GDDM 688
Query 754 FIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
K++D G+ A + + +LAPE G ++T +D + FG L+E+
Sbjct 689 HAKVADFGLVRLAPEGTQSIETKIAGTFGYLAPEYAVTG--RVTTKVDVYSFGVILMELL 746
Query 809 FDGEAPLQSRSPSEKEHF-YQRQHRLPEPSCPQ------------------LATLTSQCL 849
+A +RS E + R+ + + S P+ +A L +QC
Sbjct 747 TGRKALDVARSEEEVHLATWFRRMFINKGSFPKAIDEAMEVNEETLRSINIVAELANQCS 806
Query 850 TYEPTQRPSFRT 861
+ EP RP
Sbjct 807 SREPRDRPDMNH 818
>sp|Q9FX43|M2K9_ARATH Mitogen-activated protein kinase kinase
9 OS=Arabidopsis thaliana OX=3702 GN=MKK9 PE=1 SV=1
Length=310
Score = 213 bits (543), Expect = 1e-60, Method: Composition-based stats.
Identities = 75/311 (24%), Positives = 127/311 (41%), Gaps = 25/311 (8%)
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920
+ L + + + + + L+K+ LG G+ G V Y +
Sbjct 11 NLRLPLPPISDRRFSTSSSSATTTTVAGCNGISACDLEKLNVLGCGNGGIV----YKVRH 66
Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
T E+ A+K + D P +E++ILR +++K G E + ++MEY
Sbjct 67 KTTSEIYALKTVNGDMDPIFTRQLMREMEILRRTDSPYVVKCHGIFEKPVVGEVSILMEY 126
Query 981 VPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040
+ G+L R + +L FA+QI +G++YLHA +HRD+ N+LL++ VKI
Sbjct 127 MDGGTLESL--RGGVTEQKLAGFAKQILKGLSYLHALKIVHRDIKPANLLLNSKNEVKIA 184
Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-----YASDVWSFGVTLYELL 1095
DFG++K + + + +PE YA D+WSFG+ + ELL
Sbjct 185 DFGVSKILVRSLD---SCNSYVGTCAYMSPERFDSESSGGSSDIYAGDIWSFGLMMLELL 241
Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155
P + L + GE P+ C E ++ C +
Sbjct 242 VGHFPLLPPGQR-----------PDWATLMCAVCFGEPPRAPEGCSEEFRSFVECCLRKD 290
Query 1156 ASFRPTFENLI 1166
+S R T L+
Sbjct 291 SSKRWTAPQLL 301
Score = 163 bits (412), Expect = 4e-43, Method: Composition-based stats.
Identities = 57/295 (19%), Positives = 102/295 (35%), Gaps = 50/295 (17%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
++ +L+ LG G VY+ R + + D DP+
Sbjct 46 DLEKLNVLGCGNGGIVYKVRHKTTSEIYALKTVNGDMDPIF------------------- 86
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRG--PENIMVTEYVEHGPLDVWLRRERGH 705
++ + ++ HG+ + E ++ EY++ G L+ RG
Sbjct 87 ----TRQLMREMEILRRTDSPYVVKCHGIFEKPVVGEVSILMEYMDGGTLESL----RGG 138
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763
V A+Q+ LSYL +VH ++ N+LL +K++D GV
Sbjct 139 VTEQKLAGFAKQILKGLSYLHALKIVHRDIKPANLLLNSKNE-------VKIADFGVSKI 191
Query 764 --LGALSREERVERIPWLAPECLPGGANSLST---AMDKWGFGATLLEICFDGEAP--LQ 816
S V +++PE ++ S+ A D W FG +LE+ G P
Sbjct 192 LVRSLDSCNSYVGTCAYMSPERFDSESSGGSSDIYAGDIWSFGLMMLELLV-GHFPLLPP 250
Query 817 SRSPSEKEHFY----QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P R PE + + CL + ++R + +L
Sbjct 251 GQRPDWATLMCAVCFGEPPRAPEGCSEEFRSFVECCLRKDSSKRWTAPQLLAHPF 305
>sp|P53666|LIMK2_CHICK LIM domain kinase 2 OS=Gallus gallus OX=9031
GN=LIMK2 PE=2 SV=1
Length=642
Score = 223 bits (568), Expect = 1e-60, Method: Composition-based stats.
Identities = 77/302 (25%), Positives = 129/302 (43%), Gaps = 38/302 (13%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
+F L LG+G FG+ T+ TG+++ +K L C + + + E+
Sbjct 323 QQIFRPCDLIHGEVLGKGFFGQ----AIKVTHKATGKVMVMKEL-IRCDEETQKTFLTEV 377
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQI 1007
++R+L H +++K+ G +K L L+ EY+ G+L+D+L Q + FA+ I
Sbjct 378 KVMRSLDHPNVLKFIGVLYK--DKKLNLLTEYIEGGTLKDFLRNADPFPWQQKVSFAKGI 435
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV---------- 1057
GMAYLH+ IHRDL + N L+ D+ V + DFGL++ + E + +
Sbjct 436 ASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKKPTLEKPSAKKRTL 495
Query 1058 -------REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
R +W APE L + D++SFG+ L E++ + + L+
Sbjct 496 RKSDRKKRYTVVGNPYWMAPEMLNGQSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLD 555
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
G L + + P CP + L C E RP F L +
Sbjct 556 F-----GLNVKLFWEKFV--------PADCPPAFFPLAAICCRLEPESRPPFSKLEDSFE 602
Query 1171 TV 1172
+
Sbjct 603 AL 604
Score = 196 bits (499), Expect = 2e-51, Method: Composition-based stats.
Identities = 65/349 (19%), Positives = 112/349 (32%), Gaps = 63/349 (18%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
+ P E L++ R S + S S ++ LG+G +
Sbjct 292 KSPGPSSPKEP--LLLSRDISRSESLRSSSSCSQQIFRPCDLIHGEVLGKGFFGQAIKVT 349
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667
+ G +V+K L + F +M + H
Sbjct 350 HKATGK------------------------VMVMKELIRCDEETQKTFLTEVKVMRSLDH 385
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
++ GV + + ++TEY+E G L +LR P K+ A+ +AS ++YL +
Sbjct 386 PNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRNAD-PFPWQQKVSFAKGIASGMAYLHS 444
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----------------------- 764
++H ++ N L+ + ++D G+
Sbjct 445 MCIIHRDLNSHNCLI-------KLDKTVVVADFGLSRLIVEERKKPTLEKPSAKKRTLRK 497
Query 765 -GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--FDGEAPLQSRSPS 821
R V W+APE L G S +D + FG L EI + R+
Sbjct 498 SDRKKRYTVVGNPYWMAPEMLNG--QSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLD 555
Query 822 EKEHFY-QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ + +P P L + C EP RP F + L
Sbjct 556 FGLNVKLFWEKFVPADCPPAFFPLAAICCRLEPESRPPFSKLEDSFEAL 604
>sp|Q96TL5|HOG1_NEUCR Mitogen-activated protein kinase hog-1 OS=Neurospora
crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71
/ DSM 1257 / FGSC 987) OX=367110 GN=hog-1 PE=1 SV=1
Length=358
Score = 215 bits (547), Expect = 2e-60, Method: Composition-based stats.
Identities = 65/284 (23%), Positives = 108/284 (38%), Gaps = 29/284 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VA+K + K P +E+ +L+ L HE++
Sbjct 24 QPVGMGAFGLVC----SAKDQLTNQNVAIKKIMKPFSTPVLAKRTYRELKLLKHLRHENV 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L + ER P + L++ + R T +
Sbjct 252 SLPKRERQPLKNKFKNADSSAVDLLERMLVFDPKKRITATEALS 295
Score = 129 bits (324), Expect = 5e-31, Method: Composition-based stats.
Identities = 36/231 (16%), Positives = 75/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E D + M + +D+ V +K ++ P +A Y
Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSAKDQLTNQNVAIKKIMKPFSTPVLAKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo
sapiens OX=9606 GN=NUAK2 PE=1 SV=1
Length=628
Score = 223 bits (567), Expect = 2e-60, Method: Composition-based stats.
Identities = 69/291 (24%), Positives = 116/291 (40%), Gaps = 32/291 (11%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-- 936
+ + + LG+G +GKV + +G +VA+K+++ D
Sbjct 35 MKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKAR-----ESSGRLVAIKSIRKDKIK 89
Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSI 995
Q ++EI+I+ +L H HII E+ + + +VMEY G L DY+ R +
Sbjct 90 DEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSK--IVIVMEYASRGDLYDYISERQQL 147
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ F +QI + Y H +HRDL N+LLD + +KI DFGL+ +G
Sbjct 148 SEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQG---- 203
Query 1056 RVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ + + +PE + + D WS GV LY L+ K
Sbjct 204 KFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKI------ 257
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L + + G P P + L++ + R T E++
Sbjct 258 ---------LVKQISNGAYREPPK--PSDACGLIRWLLMVNPTRRATLEDV 297
Score = 174 bits (441), Expect = 4e-44, Method: Composition-based stats.
Identities = 59/330 (18%), Positives = 98/330 (30%), Gaps = 45/330 (14%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEIT----QLSHLGQGTRTNV 603
RR + G SP+ L Q + + L LG+GT V
Sbjct 8 RRSGPTPSAAELARPLAEGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKV 67
Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETAS 660
+ R V +K + +
Sbjct 68 KKAR-------------------------ESSGRLVAIKSIRKDKIKDEQDLMHIRREIE 102
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
+MS ++H H+ +H V + ++V EY G L ++ ER + +Q+ S
Sbjct 103 IMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYI-SERQQLSEREARHFFRQIVS 161
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIP 777
A+ Y +VH ++ NILL + IK++D G+ +
Sbjct 162 AVHYCHQNRVVHRDLKLENILLD-------ANGNIKIADFGLSNLYHQGKFLQTFCGSPL 214
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS 837
+ +PE + G + +D W G L I G P P
Sbjct 215 YASPEIVNGKPYT-GPEVDSWSLGVLLY-ILVHGTMPFDGHDHKILVKQISNGAYREPPK 272
Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
L L PT+R + +
Sbjct 273 PSDACGLIRWLLMVNPTRRATLEDVASHWW 302
>sp|Q9C7T7|CEPR2_ARATH Receptor protein-tyrosine kinase CEPR2
OS=Arabidopsis thaliana OX=3702 GN=CEPR2 PE=1 SV=1
Length=977
Score = 229 bits (583), Expect = 2e-60, Method: Composition-based stats.
Identities = 76/301 (25%), Positives = 123/301 (41%), Gaps = 23/301 (8%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
+ V L + +G G GKV G VAVK LK G +
Sbjct 670 FHQMELDVDEICRLDEDHVIGSGSAGKVYRVDLKKG----GGTVAVKWLKRGGGEEGDGT 725
Query 944 WK--QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------SI 995
E++IL + H +++K C +G + LV E++ G+L L + +
Sbjct 726 EVSVAEMEILGKIRHRNVLKLYACLVGRGSR--YLVFEFMENGNLYQALGNNIKGGLPEL 783
Query 996 GLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
+ A +G+AYLH IHRD+ + N+LLD D KI DFG+AK +G+
Sbjct 784 DWLKRYKIAVGAAKGIAYLHHDCCPPIIHRDIKSSNILLDGDYESKIADFGVAKVADKGY 843
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112
E+ V + APE +K SDV+SFGV L EL+T + + +++
Sbjct 844 EWSCVA----GTHGYMAPELAYSFKATEKSDVYSFGVVLLELVTGLRPMEDEFGEGKDIV 899
Query 1113 GIAQGQM--TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
Q+ L +L++ ++ V + C + RP+ ++ L
Sbjct 900 DYVYSQIQQDPRNLQNVLDKQVLSTYIEESMIRVLKMGLLCTTKLPNLRPSMREVVRKLD 959
Query 1171 T 1171
Sbjct 960 D 960
Score = 175 bits (444), Expect = 2e-43, Method: Composition-based stats.
Identities = 51/289 (18%), Positives = 100/289 (35%), Gaps = 47/289 (16%)
Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRT 601
F+LR + S + A A + + Q+ + + + +G G+
Sbjct 636 SGLFALRYRVVKIRELDSENRDINKADAKWKIASFHQMELDVDEICRLDEDHVIGSGSAG 695
Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF---YET 658
VY L+ G V +K L +
Sbjct 696 KVYRVDLKKGGG------------------------TVAVKWLKRGGGEEGDGTEVSVAE 731
Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVP-MAW--KMVV 714
++ ++ H ++ ++ V +V E++E+G L L +G +P + W + +
Sbjct 732 MEILGKIRHRNVLKLYACLVGRGSRYLVFEFMENGNLYQALGNNIKGGLPELDWLKRYKI 791
Query 715 AQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---GALS 768
A A ++YL + ++H ++ NILL + K++D GV
Sbjct 792 AVGAAKGIAYLHHDCCPPIIHRDIKSSNILLDGDYES-------KIADFGVAKVADKGYE 844
Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
++APE + + D + FG LLE+ G P++
Sbjct 845 WSCVAGTHGYMAPELA--YSFKATEKSDVYSFGVVLLELV-TGLRPMED 890
>sp|Q702W0|HOG1_BLAAD Mitogen-activated protein kinase hog1 OS=Blastobotrys
adeninivorans OX=409370 GN=hog1 PE=1 SV=1
Length=400
Score = 216 bits (550), Expect = 2e-60, Method: Composition-based stats.
Identities = 67/307 (22%), Positives = 111/307 (36%), Gaps = 37/307 (12%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQ 939
+ + +G G FG V + T + VA+K + K P
Sbjct 4 FIRTQIFGTCFEITSRYVDLNPVGMGAFGLVC----SARDQLTNQNVAIKKIMKPFSTPV 59
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ 999
+E+ +L+ L HE++I E + V E + L L +
Sbjct 60 LAKRTYRELKLLKHLRHENLITLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEHQF 117
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
+ F QI G+ Y+H+ +HRDL N+L++ + +KI DFGLA+ Y
Sbjct 118 IQYFLYQILRGLKYVHSAGVVHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---- 173
Query 1060 DGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ---------------- 1102
S ++ APE + K+ D+WS G E+L
Sbjct 174 --VSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMLRGKPLFPGKDHVHQFSIITELLG 231
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP---CEVYHLMKNCWETEASFR 1159
+PP +E IG L + L + ER+P K P + L++ + R
Sbjct 232 NPPDDVIETIGSEN----TLNFVKSLPKRERIPLSQKFPNADPDAVDLLEKMLVFDPRKR 287
Query 1160 PTFENLI 1166
+ +
Sbjct 288 INAADAL 294
Score = 132 bits (332), Expect = 9e-32, Method: Composition-based stats.
Identities = 37/213 (17%), Positives = 69/213 (32%), Gaps = 18/213 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + RD+ V +K ++ P +A Y
Sbjct 10 FGTCFEITSRYVDLNPVGMGAF---GLVCSARDQLTNQNVAIKKIMKPFSTPVLAKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H +L + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENLITLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEHQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ APE + +D W G E+
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML 208
>sp|Q9FLV4|Y5248_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At5g24080 OS=Arabidopsis thaliana OX=3702
GN=At5g24080 PE=2 SV=1
Length=872
Score = 228 bits (580), Expect = 2e-60, Method: Composition-based stats.
Identities = 65/300 (22%), Positives = 122/300 (41%), Gaps = 19/300 (6%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
+ LG G FG V +VAVK L R +
Sbjct 520 FTYRDLQNCTNNFSQLLGSGGFGTVYKGTVAGE-----TLVAVKRLDRALSHGERE-FIT 573
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLL 1001
E++ + +++H ++++ G C + + LV EY+ GSL ++ +
Sbjct 574 EVNTIGSMHHMNLVRLCGYCSEDSHR--LLVYEYMINGSLDKWIFSSEQTANLLDWRTRF 631
Query 1002 LFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
A +G+AY H Q IH D+ N+LLD++ K+ DFGLAK + G E+ V
Sbjct 632 EIAVATAQGIAYFHEQCRNRIIHCDIKPENILLDDNFCPKVSDFGLAKMM--GREHSHVV 689
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQG 1117
+ APE + +DV+S+G+ L E++ + S + G A
Sbjct 690 TMIRGTRGYLAPEWVSNRPITVKADVYSYGMLLLEIVGGRRNLDMSYDAEDFFYPGWAYK 749
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
++T + +++ + ++ + + C + E S RP+ ++ +L+ ++
Sbjct 750 ELTNGTSLKAVDKRLQGVAEEEEVVKALKVAFWCIQDEVSMRPSMGEVVKLLEGTSDEIN 809
Score = 192 bits (488), Expect = 5e-49, Method: Composition-based stats.
Identities = 61/327 (19%), Positives = 110/327 (34%), Gaps = 55/327 (17%)
Query 517 EGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL 576
G + + + L L ++L R + ++LI+ SP +
Sbjct 467 HGLRQKVLVIPIVVGMLVLVALLGMLLYYNLDRKRTLKRAAKNSLILC----DSPVSFTY 522
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
L +QL LG G VY+G + E
Sbjct 523 RDLQNC---TNNFSQL--LGSGGFGTVYKGTVAG-------------------------E 552
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +K LD + F + + + H +L + G C ++V EY+ +G LD
Sbjct 553 TLVAVKRLDRALSHGEREFITEVNTIGSMHHMNLVRLCGYCSEDSHRLLVYEYMINGSLD 612
Query 697 VWLRRER---GHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEG 750
W+ + + +A A ++Y + ++H ++ NILL
Sbjct 613 KWIFSSEQTANLLDWRTRFEIAVATAQGIAYFHEQCRNRIIHCDIKPENILLD------- 665
Query 751 TSPFIKLSDPGVGLGALSREERVERI-----PWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ K+SD G+ V + +LAPE + ++ D + +G LL
Sbjct 666 DNFCPKVSDFGLAKMMGREHSHVVTMIRGTRGYLAPEWVSN--RPITVKADVYSYGMLLL 723
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHR 832
EI G L +E + ++
Sbjct 724 EIV-GGRRNLDMSYDAEDFFYPGWAYK 749
>sp|Q5R7G9|NUAK2_PONAB NUAK family SNF1-like kinase 2 OS=Pongo
abelii OX=9601 GN=NUAK2 PE=2 SV=1
Length=628
Score = 223 bits (567), Expect = 2e-60, Method: Composition-based stats.
Identities = 69/291 (24%), Positives = 116/291 (40%), Gaps = 32/291 (11%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-- 936
+ + + LG+G +GKV + +G +VA+K+++ D
Sbjct 35 MKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKAR-----ESSGRLVAIKSIRKDKIK 89
Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSI 995
Q ++EI+I+ +L H HII E+ + + +VMEY G L DY+ R +
Sbjct 90 DEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSK--IVIVMEYASRGDLYDYISERQQL 147
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ F +QI + Y H +HRDL N+LLD + +KI DFGL+ +G
Sbjct 148 SEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQG---- 203
Query 1056 RVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ + + +PE + + D WS GV LY L+ K
Sbjct 204 KFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKI------ 257
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L + + G P P + L++ + R T E++
Sbjct 258 ---------LVKQISNGAYREPPK--PSDACGLIRWLLMVNPTRRATLEDV 297
Score = 174 bits (441), Expect = 4e-44, Method: Composition-based stats.
Identities = 59/330 (18%), Positives = 98/330 (30%), Gaps = 45/330 (14%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEIT----QLSHLGQGTRTNV 603
RR + G SP+ L Q + + L LG+GT V
Sbjct 8 RRSGPTPSAAELARPLAEGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKV 67
Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETAS 660
+ R V +K + +
Sbjct 68 KKAR-------------------------ESSGRLVAIKSIRKDKIKDEQDLMHIRREIE 102
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720
+MS ++H H+ +H V + ++V EY G L ++ ER + +Q+ S
Sbjct 103 IMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYI-SERQQLSEREARHFFRQIVS 161
Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIP 777
A+ Y +VH ++ NILL + IK++D G+ +
Sbjct 162 AVHYCHQNRVVHRDLKLENILLD-------ANGNIKIADFGLSNLYHQGKFLQTFCGSPL 214
Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS 837
+ +PE + G + +D W G L I G P P
Sbjct 215 YASPEIVNGKPYT-GPEVDSWSLGVLLY-ILVHGTMPFDGHDHKILVKQISNGAYREPPK 272
Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
L L PT+R + +
Sbjct 273 PSDACGLIRWLLMVNPTRRATLEDVASHWW 302
>sp|A9S9Q8|MPK4B_PHYPA Mitogen-activated protein kinase 4b OS=Physcomitrium
patens OX=3218 GN=MPK4b PE=1 SV=1
Length=380
Score = 215 bits (548), Expect = 2e-60, Method: Composition-based stats.
Identities = 77/324 (24%), Positives = 122/324 (38%), Gaps = 32/324 (10%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL- 932
+ + ++Y+ IR +G G +G V N TGE VA+K +
Sbjct 20 PTHNGEYTQYNIFGNLFEVSRKYVPPIRPIGRGAYGIVC----SAVNSETGEEVAIKKIG 75
Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL---QLVMEYVPLGSLRDY 989
A +EI +LR + HE+I+ + ++ +V E + L
Sbjct 76 NAFDNRIDAKRTLREIKLLRHMDHENIVAIRDIIRPPTRENFNDVYIVYELMD-TDLHQI 134
Query 990 LP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ + F Q+ G+ Y+H+ +HRDL N+LL+ + +KI DFGLA+
Sbjct 135 IRSNQPLTEDHCQYFLYQLLRGLKYIHSAKVLHRDLKPSNLLLNANCDLKICDFGLARTT 194
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQSPPT- 1106
E + ++ APE L ++ A DVWS G ELL
Sbjct 195 SETD----FMTEYVVTRWYRAPELLLNCSEYTAAIDVWSVGCIFMELLNREPLFPGRDYV 250
Query 1107 ----KFLELIGIAQGQ-------MTVLRLTELLERGERLPRPDKCP---CEVYHLMKNCW 1152
ELIG + R L R R P K P L+++
Sbjct 251 QQLRLITELIGSPEDHDLGFLRSDNARRYIRQLPRFARQPLDRKFPNMGPAAIDLVEHML 310
Query 1153 ETEASFRPTFENLI--PILKTVHE 1174
+ + R T E + P L T+H+
Sbjct 311 RFDPARRITVEEALAHPYLATLHD 334
Score = 133 bits (334), Expect = 4e-32, Method: Composition-based stats.
Identities = 37/236 (16%), Positives = 77/236 (33%), Gaps = 44/236 (19%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
V +K + + +G+G V G V +K
Sbjct 37 EVSRKYVPPIRPIGRGAYGIVCSAVNSETGE------------------------EVAIK 72
Query 643 VLDPSHHDIALAF--YETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPL 695
+ + + A L+ + H ++ + + + +V E ++ L
Sbjct 73 KIGNAFDNRIDAKRTLREIKLLRHMDHENIVAIRDIIRPPTRENFNDVYIVYELMD-TDL 131
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + QL L Y+ + ++H ++ N+LL + +
Sbjct 132 HQIIRSNQ-PLTEDHCQYFLYQLLRGLKYIHSAKVLHRDLKPSNLLLN-------ANCDL 183
Query 756 KLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
K+ D G+ + E V + APE L + + A+D W G +E+
Sbjct 184 KICDFGLARTTSETDFMTEYVVTRWYRAPELLLNCSE-YTAAIDVWSVGCIFMELL 238
>sp|Q54EY4|DST3_DICDI Serine/threonine-protein kinase dst3 OS=Dictyostelium
discoideum OX=44689 GN=dst3 PE=3 SV=1
Length=562
Score = 221 bits (563), Expect = 2e-60, Method: Composition-based stats.
Identities = 67/273 (25%), Positives = 114/273 (42%), Gaps = 28/273 (10%)
Query 903 LGEGHFGKVSLYCY---DPTNDGTGEMVAVKALKADCGPQHRS-GWKQEIDILRT-LYHE 957
+G G FG V + ++A K ++ + + +EIDIL+ +
Sbjct 29 VGSGSFGTVCACRWMKKKDRESNGNRLIACKFVEVNADDVETNLNLVKEIDILKESMDCP 88
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLH 1015
+I++YKGC L +VMEY GSL D + + ++ + +G+ YLH
Sbjct 89 YIVEYKGCYLKSS--MLLIVMEYCKGGSLLDIIELCGKRLIEEEIAAVCAGVVKGLVYLH 146
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
++ HRD+ A NVLLD + L K+ DFG++ +G + V +W APE +
Sbjct 147 SKRTTHRDIKAGNVLLDEEGLPKLADFGVSTIAEQGQKMNTV----IGSPYWMAPEIIMG 202
Query 1076 YKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+ +D+WS G+T E+ PP++ + I + L
Sbjct 203 QGYDQKADIWSLGITAIEIAELVPPRFDVPPSRVIFTIPH--------------QPPPSL 248
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P E +K C + RP+ + L+
Sbjct 249 KIPSDWSPEFNDFVKQCLSMNPALRPSAQQLLS 281
Score = 182 bits (463), Expect = 2e-47, Method: Composition-based stats.
Identities = 61/313 (19%), Positives = 102/313 (33%), Gaps = 38/313 (12%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQL-SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
S NL + D + I Q+ +G G+ V R +
Sbjct 2 NSDSVENLFISRISKDDPEAIFQIVEVVGSGSFGTVCACRWMKK---------------- 45
Query 628 VPGRDRGQELRVVLK--VLDPSHHDIALAFYETASLMS-QVSHTHLAFVHGVCVRGPENI 684
R+ + K ++ + L + ++ + ++ G ++ +
Sbjct 46 -KDRESNGNRLIACKFVEVNADDVETNLNLVKEIDILKESMDCPYIVEYKGCYLKSSMLL 104
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+V EY + G L + + V + L YL +K H ++ N+LL
Sbjct 105 IVMEYCKGGSLLDIIELCGKRLIEEEIAAVCAGVVKGLVYLHSKRTTHRDIKAGNVLLDE 164
Query 745 LGLAEGTSPFIKLSDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
GL KL+D GV + W+APE + G D W G
Sbjct 165 EGLP-------KLADFGVSTIAEQGQKMNTVIGSPYWMAPEIIMG--QGYDQKADIWSLG 215
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQH----RLPEPSCPQLATLTSQCLTYEPTQRP 857
T +EI P PS Q ++P P+ QCL+ P RP
Sbjct 216 ITAIEIAEL-VPPRFDVPPSRVIFTIPHQPPPSLKIPSDWSPEFNDFVKQCLSMNPALRP 274
Query 858 SFRTILRDLTRLQ 870
S + +L L+
Sbjct 275 SAQQLLSHPFILK 287
>sp|Q5I6M2|HOG1_EXSTU Mitogen-activated protein kinase HOG1 OS=Exserohilum
turcicum OX=93612 GN=HOG1 PE=2 SV=2
Length=329
Score = 214 bits (544), Expect = 2e-60, Method: Composition-based stats.
Identities = 67/272 (25%), Positives = 105/272 (39%), Gaps = 29/272 (11%)
Query 905 EGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963
G FG V + T + VAVK + K P +E+ +L+ L HE+II
Sbjct 1 MGAFGLVC----SAKDQLTNQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENIISLS 56
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRD 1023
E + V E + L L + + F QI G+ Y+H+ +HRD
Sbjct 57 DIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYIHSAGVVHRD 114
Query 1024 LAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKFYYAS 1082
L N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 115 LKPSNILVNENCDLKICDFGLARIQDPQVTGY------VSTRYYRAPEIMLTWQKYDVEV 168
Query 1083 DVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTELLER 1130
D+WS G E+L + + EL+G + LR + L +
Sbjct 169 DIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVQPLPK 228
Query 1131 GERLP---RPDKCPCEVYHLMKNCWETEASFR 1159
ER P + E L++N + R
Sbjct 229 RERQPLANKFKNAEPEAVDLLENMLVFDPRKR 260
Score = 132 bits (333), Expect = 2e-32, Method: Composition-based stats.
Identities = 33/210 (16%), Positives = 71/210 (34%), Gaps = 16/210 (8%)
Query 621 MDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCV 678
M + +D+ V +K ++ P ++ Y L+ + H ++ + + +
Sbjct 1 MGAFGLVCSAKDQLTNQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENIISLSDIFI 60
Query 679 RG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737
+ VTE + L L + + Q+ L Y+ + +VH ++
Sbjct 61 SPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLYQILRGLKYIHSAGVVHRDLKP 117
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVERIPWLAPECLPGGANSLSTAMD 796
NIL+ + +K+ D G+ V + APE + +D
Sbjct 118 SNILVNE-------NCDLKICDFGLARIQDPQVTGYVSTRYYRAPE-IMLTWQKYDVEVD 169
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
W G E+ +G+ + +
Sbjct 170 IWSAGCIFAEML-EGKPLFPGKDHVNQFSI 198
>sp|Q9R0A5|NEK3_MOUSE Serine/threonine-protein kinase Nek3 OS=Mus
musculus OX=10090 GN=Nek3 PE=1 SV=2
Length=511
Score = 219 bits (559), Expect = 2e-60, Method: Composition-based stats.
Identities = 66/267 (25%), Positives = 115/267 (43%), Gaps = 29/267 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FG+ L + + + A+K ++ S ++E +L + H +I+ +
Sbjct 10 IGQGSFGRALLV----LQESSNQTFAMKEIRLLKSDTQTS--RKEAVLLAKMKHPNIVAF 63
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHY 1019
K E E L +VMEY G L + + +L + QIC G+ ++H +
Sbjct 64 KESFE--AEGYLYIVMEYCDGGDLMQRIKQQKGKLFPEDTILNWFIQICLGVNHIHKRRV 121
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRD+ ++NV L ++ VK+GDFG A+ + + ++ PE + +
Sbjct 122 LHRDIKSKNVFLTHNGKVKLGDFGSARLLSSPMAFACT---YVGTPYYVPPEIWENLPYN 178
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SD+WS G LYEL Q+ K L L + +G P P
Sbjct 179 NKSDIWSLGCILYELCALKHPFQANSWKNLIL---------------KICQGPIHPLPAL 223
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLI 1166
C++ L+K + S RP+ L+
Sbjct 224 YSCKLQGLVKQMLKRNPSHRPSATTLL 250
Score = 162 bits (410), Expect = 5e-41, Method: Composition-based stats.
Identities = 50/285 (18%), Positives = 94/285 (33%), Gaps = 40/285 (14%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
T L +GQG+ + +K +
Sbjct 1 MDNYTVLRVIGQGSFGR------------------------ALLVLQESSNQTFAMKEIR 36
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
D + + A L++++ H ++ +V EY + G L +++++G
Sbjct 37 LLKSDTQTS-RKEAVLLAKMKHPNIVAFKESFEAEGYLYIVMEYCDGGDLMQRIKQQKGK 95
Query 706 V-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ P + Q+ ++++ + ++H ++ +N+ L G +KL D G
Sbjct 96 LFPEDTILNWFIQICLGVNHIHKRRVLHRDIKSKNVFLTHNG-------KVKLGDFGSAR 148
Query 765 GALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
S V ++ PE + D W G L E+C +
Sbjct 149 LLSSPMAFACTYVGTPYYVPPEIWEN--LPYNNKSDIWSLGCILYELCALKHPFQANSWK 206
Query 821 SEKEHFYQR-QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ Q H LP +L L Q L P+ RPS T+L
Sbjct 207 NLILKICQGPIHPLPALYSCKLQGLVKQMLKRNPSHRPSATTLLC 251
>sp|Q55A55|Y9848_DICDI Probable serine/threonine-protein kinase
DDB_G0272092 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0272092
PE=2 SV=1
Length=986
Score = 229 bits (583), Expect = 2e-60, Method: Composition-based stats.
Identities = 68/294 (23%), Positives = 113/294 (38%), Gaps = 19/294 (6%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
V ++ L LG G GKV + G+ VA+K LK+ + + +K+E
Sbjct 594 WVIDEKTLTYNVLLGTGASGKVYKGTF------NGQEVAIKVLKSFTDKKDIAEFKKEFQ 647
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQI 1007
I+ L ++ + G + L +VMEY GSL L + Q
Sbjct 648 IVSALRAPGVVYFHGA---GIKDKLCIVMEYCSRGSLYHILKDDTTQFTWDNFFNLGTQA 704
Query 1008 CEGMAYLHA--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
+ LH +HRDL + N+L+ + VKI DFGL++ +
Sbjct 705 INSLDSLHNWTPQVLHRDLKSLNLLVTENWTVKICDFGLSRF--DTGSNLETLGKLRGTY 762
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+ APE K+ SDV+S G+ L+E+ C T L + L
Sbjct 763 AYVAPEVYFGKKYTTKSDVYSMGIILWEMTYRCIKG----THLLPYAEYPHLKFDYQILI 818
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
++ R P+ P + +L+ +++ RPT L + ++Y
Sbjct 819 SSAKKDVRPTTPENAPESLKNLIARTLVKDSTLRPTTLEFYEELLKIRDEYNAN 872
Score = 159 bits (401), Expect = 4e-38, Method: Composition-based stats.
Identities = 57/316 (18%), Positives = 105/316 (33%), Gaps = 56/316 (18%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
+D+K +T LG G VY+G GQE
Sbjct 590 DSDSWVIDEKTLTYNVLLGTGASGKVYKG------------------------TFNGQE- 624
Query 638 RVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
V +KVL + F + ++S + + + HG ++ + +V EY G L
Sbjct 625 -VAIKVLKSFTDKKDIAEFKKEFQIVSALRAPGVVYFHGAGIK-DKLCIVMEYCSRGSLY 682
Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGLAEGTSPF 754
L+ + + Q ++L L N ++H ++ N+L+ +
Sbjct 683 HILKDDTTQFTWDNFFNLGTQAINSLDSLHNWTPQVLHRDLKSLNLLVTE-------NWT 735
Query 755 IKLSDPGVGLGALSRE-----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
+K+ D G+ + ++APE G +T D + G L E+ +
Sbjct 736 VKICDFGLSRFDTGSNLETLGKLRGTYAYVAPEVYFG--KKYTTKSDVYSMGIILWEMTY 793
Query 810 DGEAPLQSRSPSEKEHFYQRQHRL------------PEPSCPQLATLTSQCLTYEPTQRP 857
+E H L PE + L L ++ L + T RP
Sbjct 794 RCIKGTHLLPYAEYPHLKFDYQILISSAKKDVRPTTPENAPESLKNLIARTLVKDSTLRP 853
Query 858 SFRTILRDLTRLQPHN 873
+ +L +++
Sbjct 854 TTLEFYEELLKIRDEY 869
>sp|Q15569|TESK1_HUMAN Dual specificity testis-specific protein
kinase 1 OS=Homo sapiens OX=9606 GN=TESK1 PE=1 SV=2
Length=626
Score = 223 bits (567), Expect = 2e-60, Method: Composition-based stats.
Identities = 73/290 (25%), Positives = 122/290 (42%), Gaps = 28/290 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+G G F +V Y + +G+++ LK + P +R +E+ ++ L H
Sbjct 57 FHCAEKIGAGFFSEV----YKVRHRQSGQVM---VLKMNKLPSNRGNTLREVQLMNRLRH 109
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLH 1015
+I+++ G C QG+ L + EY+ G+L L + L A I G+ YLH
Sbjct 110 PNILRFMGVCVHQGQ--LHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIARGLRYLH 167
Query 1016 AQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVRE-DGDSPVFWYAPE 1071
++ HRDL ++N L+ D +GDFGLA+ +P E R +W APE
Sbjct 168 SKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPE 227
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
L+ + +DV++FG+ L EL+ + + + T++
Sbjct 228 VLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVG-------- 279
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
D CP L +C E S R F + L+ + E+ AP
Sbjct 280 ------DDCPLPFLLLAIHCCNLEPSTRAPFTEITQHLEWILEQLPEPAP 323
Score = 194 bits (492), Expect = 9e-51, Method: Composition-based stats.
Identities = 70/311 (23%), Positives = 111/311 (36%), Gaps = 45/311 (14%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
+S R L + S RVD + +G G + VY+ R
Sbjct 39 SSYRALRSAVSSLARVD--DFHCAEKIGAGFFSEVYKVRH-------------------- 76
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
R GQ + + + L + + LM+++ H ++ GVCV + +TE
Sbjct 77 --RQSGQVMVLKMNKLPSNRGNT----LREVQLMNRLRHPNILRFMGVCVHQGQLHALTE 130
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
Y+ G L+ L + ++ +A +A L YL +K + H ++ +N L+ R
Sbjct 131 YMNGGTLEQLLSSPE-PLSWPVRLHLALDIARGLRYLHSKGVFHRDLTSKNCLVRR---- 185
Query 749 EGTSPFIKLSDPGVG-LGALSREER-------VERIPWLAPECLPGGANSLSTAMDKWGF 800
E + D G+ + RE V W+APE L G D + F
Sbjct 186 EDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGEL--YDEKADVFAF 243
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-LPEPSCP-QLATLTSQCLTYEPTQRPS 858
G L E+ A +E R L CP L C EP+ R
Sbjct 244 GIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGDDCPLPFLLLAIHCCNLEPSTRAP 303
Query 859 FRTILRDLTRL 869
F I + L +
Sbjct 304 FTEITQHLEWI 314
>sp|Q7YQL3|PAK3_PONPY Serine/threonine-protein kinase PAK 3 OS=Pongo
pygmaeus OX=9600 GN=PAK3 PE=2 SV=1
Length=559
Score = 221 bits (562), Expect = 2e-60, Method: Composition-based stats.
Identities = 66/318 (21%), Positives = 120/318 (38%), Gaps = 23/318 (7%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
T + + T+ R+ R + + + + K+ + +G+G G
Sbjct 236 TPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASG 295
Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
V Y + TG+ VA+K + P+ + EI ++R + +I+ Y
Sbjct 296 TV----YTALDIATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVG 350
Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029
E L +VMEY+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+
Sbjct 351 DE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNI 408
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
LL D VK+ DFG + R +W APE + + D+WS G+
Sbjct 409 LLGMDGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGI 465
Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149
E++ PP + T L P++ +
Sbjct 466 MAIEMV-----EGEPPYLNENPLRALYLIATNGT--------PELQNPERLSAVFRDFLN 512
Query 1150 NCWETEASFRPTFENLIP 1167
C E + R + + L+
Sbjct 513 RCLEMDVDRRGSAKELLQ 530
Score = 178 bits (451), Expect = 6e-46, Method: Composition-based stats.
Identities = 54/291 (19%), Positives = 97/291 (33%), Gaps = 44/291 (15%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+K+ T+ +GQG VY D V +K +
Sbjct 279 PKKKYTRFEKIGQGASGTVY------------------------TALDIATGQEVAIKQM 314
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ +M + + ++ + G E +V EY+ G L +
Sbjct 315 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 372
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ V ++ AL +L + ++H ++ NILL G +KL+D G
Sbjct 373 CMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 425
Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
R V W+APE + A +D W G +E+ +GE P + +P
Sbjct 426 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENP 482
Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ PE ++CL + +R S + +L+
Sbjct 483 LRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPF 533
>sp|Q7YQL4|PAK3_PANTR Serine/threonine-protein kinase PAK 3 OS=Pan
troglodytes OX=9598 GN=PAK3 PE=2 SV=1
Length=559
Score = 221 bits (562), Expect = 2e-60, Method: Composition-based stats.
Identities = 66/318 (21%), Positives = 120/318 (38%), Gaps = 23/318 (7%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
T + + T+ R+ R + + + + K+ + +G+G G
Sbjct 236 TPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASG 295
Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
V Y + TG+ VA+K + P+ + EI ++R + +I+ Y
Sbjct 296 TV----YTALDIATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVG 350
Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029
E L +VMEY+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+
Sbjct 351 DE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNI 408
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
LL D VK+ DFG + R +W APE + + D+WS G+
Sbjct 409 LLGMDGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGI 465
Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149
E++ PP + T L P++ +
Sbjct 466 MAIEMV-----EGEPPYLNENPLRALYLIATNGT--------PELQNPERLSAVFRDFLN 512
Query 1150 NCWETEASFRPTFENLIP 1167
C E + R + + L+
Sbjct 513 RCLEMDVDRRGSAKELLQ 530
Score = 178 bits (451), Expect = 6e-46, Method: Composition-based stats.
Identities = 54/291 (19%), Positives = 97/291 (33%), Gaps = 44/291 (15%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+K+ T+ +GQG VY D V +K +
Sbjct 279 PKKKYTRFEKIGQGASGTVY------------------------TALDIATGQEVAIKQM 314
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ +M + + ++ + G E +V EY+ G L +
Sbjct 315 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 372
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ V ++ AL +L + ++H ++ NILL G +KL+D G
Sbjct 373 CMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 425
Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
R V W+APE + A +D W G +E+ +GE P + +P
Sbjct 426 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENP 482
Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ PE ++CL + +R S + +L+
Sbjct 483 LRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPF 533
>sp|O75914|PAK3_HUMAN Serine/threonine-protein kinase PAK 3 OS=Homo
sapiens OX=9606 GN=PAK3 PE=1 SV=2
Length=559
Score = 221 bits (562), Expect = 2e-60, Method: Composition-based stats.
Identities = 66/318 (21%), Positives = 120/318 (38%), Gaps = 23/318 (7%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
T + + T+ R+ R + + + + K+ + +G+G G
Sbjct 236 TPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASG 295
Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
V Y + TG+ VA+K + P+ + EI ++R + +I+ Y
Sbjct 296 TV----YTALDIATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVG 350
Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029
E L +VMEY+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+
Sbjct 351 DE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNI 408
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
LL D VK+ DFG + R +W APE + + D+WS G+
Sbjct 409 LLGMDGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGI 465
Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149
E++ PP + T L P++ +
Sbjct 466 MAIEMV-----EGEPPYLNENPLRALYLIATNGT--------PELQNPERLSAVFRDFLN 512
Query 1150 NCWETEASFRPTFENLIP 1167
C E + R + + L+
Sbjct 513 RCLEMDVDRRGSAKELLQ 530
Score = 178 bits (451), Expect = 6e-46, Method: Composition-based stats.
Identities = 54/291 (19%), Positives = 97/291 (33%), Gaps = 44/291 (15%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+K+ T+ +GQG VY D V +K +
Sbjct 279 PKKKYTRFEKIGQGASGTVY------------------------TALDIATGQEVAIKQM 314
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ +M + + ++ + G E +V EY+ G L +
Sbjct 315 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 372
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ V ++ AL +L + ++H ++ NILL G +KL+D G
Sbjct 373 CMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 425
Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
R V W+APE + A +D W G +E+ +GE P + +P
Sbjct 426 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENP 482
Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ PE ++CL + +R S + +L+
Sbjct 483 LRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPF 533
>sp|Q6NQ87|CRK22_ARATH Cysteine-rich receptor-like protein kinase
22 OS=Arabidopsis thaliana OX=3702 GN=CRK22 PE=2 SV=1
Length=660
Score = 223 bits (569), Expect = 2e-60, Method: Composition-based stats.
Identities = 77/335 (23%), Positives = 122/335 (36%), Gaps = 32/335 (10%)
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
C + QR F + +DV T N K LGEG
Sbjct 316 CWRRKSLQRTEFES------------DSDVSTTNSLQYEFKTIEAATNKFSKSNKLGEGR 363
Query 908 FGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
FG+V + G VAVK L G Q ++ E ++ + H ++ + G C
Sbjct 364 FGEVYKGKF-----SNGTEVAVKRLSKVSG-QDTKKFRNEAVLVSKIQHRNLARLLGFCL 417
Query 968 DQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH---YI 1020
K L+ E+V SL +L + + + I +G+ +LH I
Sbjct 418 QGDGK--FLIYEFVLNKSLDYFLFDPEKQGELDWTRRYKIIGGIAQGILHLHQDPQLTII 475
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
+RD A N+LLD D KI DFG+A ++ V + +PE KF
Sbjct 476 YRDFKASNILLDADMNPKISDFGMATVFGMEESRGNTNWIAETFV-YMSPEYAVHGKFSM 534
Query 1081 ASDVWSFGVTLYELLTHCDSS----QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
SDV+SFG+ + E+++ +S T L+ A +LL+
Sbjct 535 KSDVYSFGILILEIISGKKNSSLYQNDETTTAGNLVTYAWRLWRNGSQLKLLDSSIGRNY 594
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
H+ C + RP ++ +L +
Sbjct 595 QSNEVTRCIHIALLCVQENPEDRPKLSTIVSMLTS 629
Score = 206 bits (524), Expect = 1e-54, Method: Composition-based stats.
Identities = 62/331 (19%), Positives = 108/331 (33%), Gaps = 69/331 (21%)
Query 569 ASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
+ T N Q F ++ + ++ + LG+G VY+G+
Sbjct 331 SDVSTTNSLQYEFKTIEAATNKFSKSNKLGEGRFGEVYKGK------------------- 371
Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686
V +K L F A L+S++ H +LA + G C++G ++
Sbjct 372 ------FSNGTEVAVKRLSKVSGQDTKKFRNEAVLVSKIQHRNLARLLGFCLQGDGKFLI 425
Query 687 TEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNIL 741
E+V + LD +L + W + + +A + +L +++ + NIL
Sbjct 426 YEFVLNKSLDYFLFDPEKQGELDWTRRYKIIGGIAQGILHLHQDPQLTIIYRDFKASNIL 485
Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAM 795
L K+SD G+ E R E +++PE G S
Sbjct 486 LD-------ADMNPKISDFGMATVFGMEESRGNTNWIAETFVYMSPEYAVHG--KFSMKS 536
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSC-------------- 838
D + FG +LEI G+ E + RL
Sbjct 537 DVYSFGILILEIIS-GKKNSSLYQNDETTTAGNLVTYAWRLWRNGSQLKLLDSSIGRNYQ 595
Query 839 ----PQLATLTSQCLTYEPTQRPSFRTILRD 865
+ + C+ P RP TI+
Sbjct 596 SNEVTRCIHIALLCVQENPEDRPKLSTIVSM 626
>sp|Q940H6|SRK2E_ARATH Serine/threonine-protein kinase SRK2E OS=Arabidopsis
thaliana OX=3702 GN=SRK2E PE=1 SV=1
Length=362
Score = 214 bits (546), Expect = 2e-60, Method: Composition-based stats.
Identities = 72/285 (25%), Positives = 120/285 (42%), Gaps = 26/285 (9%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
P P + + ++D+G G+FG L + + E+VAVK + + G +
Sbjct 9 PMDLPIMHDSDRYELVKDIGSGNFGVARLM----RDKQSNELVAVKYI--ERGEKIDENV 62
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLF 1003
K+EI R+L H +I+++K L +VMEY G L + + + F
Sbjct 63 KREIINHRSLRHPNIVRFKEVILTPTH--LAIVMEYASGGELFERICNAGRFSEDEARFF 120
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDG 1061
QQ+ G++Y HA HRDL N LLD +KI DFG +K + + +
Sbjct 121 FQQLISGVSYCHAMQVCHRDLKLENTLLDGSPAPRLKICDFGYSK---SSVLHSQPKSTV 177
Query 1062 DSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
+P + APE L + ++ DVWS GVTLY +L + P + +
Sbjct 178 GTPA-YIAPEVLLKKEYDGKVADVWSCGVTLYVMLVGAYPFEDPE----------EPKNF 226
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ +L +P E HL+ + + + R + +
Sbjct 227 RKTIHRILNVQYAIPDYVHISPECRHLISRIFVADPAKRISIPEI 271
Score = 160 bits (404), Expect = 2e-41, Method: Composition-based stats.
Identities = 55/332 (17%), Positives = 98/332 (30%), Gaps = 47/332 (14%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
D + +G G RD+ V +K +
Sbjct 17 DSDRYELVKDIGSGNFG------------------------VARLMRDKQSNELVAVKYI 52
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ I + H ++ V + +V EY G L + G
Sbjct 53 ERG-EKIDENVKREIINHRSLRHPNIVRFKEVILTPTHLAIVMEYASGGELFERI-CNAG 110
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
QQL S +SY + H ++ N LL +P +K+ D G
Sbjct 111 RFSEDEARFFFQQLISGVSYCHAMQVCHRDLKLENTLLD-----GSPAPRLKICDFGYSK 165
Query 765 GAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
++ + V ++APE L D W G TL + G P + P
Sbjct 166 SSVLHSQPKSTVGTPAYIAPEVLLKKEYD-GKVADVWSCGVTLYVMLV-GAYPFED--PE 221
Query 822 EKEHFYQRQHRL---------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
E ++F + HR+ P+ L S+ +P +R S I L+
Sbjct 222 EPKNFRKTIHRILNVQYAIPDYVHISPECRHLISRIFVADPAKRISIPEIRNHEWFLKNL 281
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
+ + + + + ++ +
Sbjct 282 PADLMNDNTMTTQFDESDQPGQSIEEIMQIIA 313
>sp|Q6PHR2|ULK3_HUMAN Serine/threonine-protein kinase ULK3 OS=Homo
sapiens OX=9606 GN=ULK3 PE=1 SV=2
Length=472
Score = 218 bits (555), Expect = 2e-60, Method: Composition-based stats.
Identities = 67/280 (24%), Positives = 112/280 (40%), Gaps = 26/280 (9%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQE 947
LG G + V T E+VA+K + K E
Sbjct 6 WGPPRLDGFILTERLGSGTYATVYKAYAK---KDTREVVAIKCVAKKSLNKASVENLLTE 62
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQ 1006
I+IL+ + H HI++ K D ++ L+ME+ G L ++ R + +F QQ
Sbjct 63 IEILKGIRHPHIVQLKDFQWDSD--NIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ 120
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLD--NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+ + +LH ++ H DL +N+LL +K+ DFG A+ + E + +R
Sbjct 121 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLR----GS 176
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+ APE + + ++ D+WS GV LYE L S LE +R
Sbjct 177 PLYMAPEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELE---------EKIRS 227
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
++E R C L++ E + S R +F++
Sbjct 228 NRVIELPLRPLLSRDC----RDLLQRLLERDPSRRISFQD 263
Score = 191 bits (486), Expect = 4e-51, Method: Composition-based stats.
Identities = 66/293 (23%), Positives = 106/293 (36%), Gaps = 37/293 (13%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
LG GT VY+ + + V K L+ +
Sbjct 14 FILTERLGSGTYATVYKAYAKKDTREVVAIKC------------------VAKKSLNKAS 55
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ ++ + H H+ + ++ E+ G L ++ R +P
Sbjct 56 VEN---LLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRI-LPE 111
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
V QQLASAL +L +N+ H ++ +NILL+ L P +KL+D G
Sbjct 112 KVARVFMQQLASALQFLHERNISHLDLKPQNILLSSL-----EKPHLKLADFGFAQHMSP 166
Query 769 -REERV--ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
E+ V ++APE + +D W G L E F G+ P SRS SE E
Sbjct 167 WDEKHVLRGSPLYMAPEMV--CQRQYDARVDLWSMGVILYEALF-GQPPFASRSFSELEE 223
Query 826 FYQRQHRLPEPSCPQLA----TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
+ + P P L+ L + L +P++R SF+ H
Sbjct 224 KIRSNRVIELPLRPLLSRDCRDLLQRLLERDPSRRISFQDFFAHPWVDLEHMP 276
>sp|Q84VQ3|CIPKQ_ARATH CBL-interacting serine/threonine-protein
kinase 26 OS=Arabidopsis thaliana OX=3702 GN=CIPK26 PE=1 SV=2
Length=439
Score = 217 bits (552), Expect = 2e-60, Method: Composition-based stats.
Identities = 61/269 (23%), Positives = 111/269 (41%), Gaps = 27/269 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959
LG+G F KV N TGE VA+K L + +H+ ++EI ++ + H ++
Sbjct 18 TLGQGTFAKVRC----AVNTETGERVALKILDKEKVLKHKMAEQIRREICTMKLINHPNV 73
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
++ + + + +V+E+ G L D + + + QQ+ + Y H++
Sbjct 74 VRLYEVLASKTK--IYIVLEFGTGGELFDKIVHDGRLKEENARKYFQQLINAVDYCHSRG 131
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N+LLD +K+ DFGL+ + + +P + APE L + +
Sbjct 132 VYHRDLKPENLLLDAQGNLKVSDFGLSALSRQVRGDGLLHTACGTPN-YAAPEVLNDQGY 190
Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
A +D+WS GV L+ LL + ++ L + + GE P
Sbjct 191 DGATADLWSCGVILFVLLAGYLPFED---------------SNLMTLYKKIIAGE-YHCP 234
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+L+ + R T ++
Sbjct 235 PWLSPGAKNLIVRILDPNPMTRITIPEVL 263
Score = 166 bits (419), Expect = 9e-43, Method: Composition-based stats.
Identities = 54/296 (18%), Positives = 91/296 (31%), Gaps = 42/296 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ LGQGT V + RV LK+LD
Sbjct 12 KYEVGKTLGQGTFAKV------------------------RCAVNTETGERVALKILDKE 47
Query 648 H---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
H +A M ++H ++ ++ V + +V E+ G L + G
Sbjct 48 KVLKHKMAEQIRREICTMKLINHPNVVRLYEVLASKTKIYIVLEFGTGGELFDKI-VHDG 106
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763
+ QQL +A+ Y ++ + H ++ N+LL G +K+SD G+
Sbjct 107 RLKEENARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDAQG-------NLKVSDFGLSA 159
Query 764 -----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
G + APE L D W G L + S
Sbjct 160 LSRQVRGDGLLHTACGTPNYAAPEVLNDQGYD-GATADLWSCGVILFVLLAGYLPFEDSN 218
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
+ + ++ P P L + L P R + +L D + +
Sbjct 219 LMTLYKKIIAGEYHCPPWLSPGAKNLIVRILDPNPMTRITIPEVLGDAWFKKNYKP 274
>sp|Q6ERS4|CIPKG_ORYSJ CBL-interacting protein kinase 16 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK16 PE=2 SV=1
Length=456
Score = 217 bits (553), Expect = 3e-60, Method: Composition-based stats.
Identities = 63/271 (23%), Positives = 110/271 (41%), Gaps = 29/271 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA---DCGPQHRSGWKQEIDILRTLYHEHI 959
LG+G F KV + +GE VA+K + ++EI I+R + H ++
Sbjct 28 LGQGTFAKVYYG----RDLRSGESVAIKVIDKARLRRTEGMVEQLRREISIMRMVRHPNV 83
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ + + + +VMEY G L + R + + QQ+ + + H +
Sbjct 84 VGIREVLASRA--RVFVVMEYARGGELFAKVARGRLTEEHARRYFQQLVAAVGFCHGRGV 141
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
HRDL N+LLD + +K+ DFGLA + + + +P + APE L++ +
Sbjct 142 AHRDLKPENLLLDEEGRLKVTDFGLAALPEQLRQDGLLHTQCGTPA-YVAPEVLRKRGYD 200
Query 1080 YA-SDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
A +D+WS GV LY LL Q K + I A+ Q+ P
Sbjct 201 GARADLWSCGVVLYVLLCGFLPFQHENYAKMYQKIFKAEYQV-----------------P 243
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
+ L+ + + R + ++
Sbjct 244 PWVSGDARRLIVRLLVVDPAKRISIPEIMRT 274
Score = 169 bits (428), Expect = 9e-44, Method: Composition-based stats.
Identities = 54/289 (19%), Positives = 93/289 (32%), Gaps = 44/289 (15%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647
LGQGT VY G RD V +KV+D +
Sbjct 23 ELGRLLGQGTFAKVYYG------------------------RDLRSGESVAIKVIDKARL 58
Query 648 --HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ S+M V H ++ + V +V EY G L + + RG
Sbjct 59 RRTEGMVEQLRREISIMRMVRHPNVVGIREVLASRARVFVVMEYARGGEL--FAKVARGR 116
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763
+ QQL +A+ + + + H ++ N+LL G +K++D G+
Sbjct 117 LTEEHARRYFQQLVAAVGFCHGRGVAHRDLKPENLLLDEEGR-------LKVTDFGLAAL 169
Query 764 ----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ ++APE L D W G L +
Sbjct 170 PEQLRQDGLLHTQCGTPAYVAPEVLRKRGYD-GARADLWSCGVVLYVLLCGFLPFQHENY 228
Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ ++ ++++P L + L +P +R S I+R
Sbjct 229 AKMYQKIFKAEYQVPPWVSGDARRLIVRLLVVDPAKRISIPEIMRTPWF 277
>sp|Q8SRF5|Y823_ENCCU Probable cell division protein kinase ECU08_0230
OS=Encephalitozoon cuniculi (strain GB-M1) OX=284813
GN=ECU08_0230 PE=3 SV=1
Length=265
Score = 211 bits (536), Expect = 3e-60, Method: Composition-based stats.
Identities = 66/270 (24%), Positives = 127/270 (47%), Gaps = 20/270 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G +G+V Y+ + T E VA+K ++ + +EI IL+ L H +II
Sbjct 10 IGSGTYGEV----YEAIDTETKEKVALKRIRLNEKEGMPGTALREISILKKLSHRNIISL 65
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHR 1022
+ L +V ++ L+ Y+ ++ ++ Q+ G+ YLH + +HR
Sbjct 66 VSII--HTDALLTMVFPFIDY-ELKKYIGMNTGK--NIMELVNQLICGVHYLHRMNVVHR 120
Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFYYA 1081
DL +N+L+ +D ++KI DFGL++++ Y +++ +PE L + +
Sbjct 121 DLKPQNILVTSDGVLKIADFGLSRSLEIRVPPYSSE---VVTLWYRSPELLMGSTSYRFY 177
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
D+WS G +YE++T + +K +L I + T L ++E+ RL P
Sbjct 178 VDIWSLGCIIYEMIT-LEPLFPGESKENQLTLIRRKAGTRRSLRGMVEQ--RLAVPKF-- 232
Query 1142 CEVYHLMKNCWETEASFRPTFENLIPILKT 1171
V ++ C + + R T + ++ IL+
Sbjct 233 --VTEIIVRCLDFNYNQRITADEIMEILEN 260
Score = 147 bits (372), Expect = 3e-38, Method: Composition-based stats.
Identities = 51/288 (18%), Positives = 100/288 (35%), Gaps = 51/288 (18%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
+ +G GT VYE D + +V LK + +
Sbjct 5 ILGALIGSGTYGEVYEAI------------------------DTETKEKVALKRIRLNEK 40
Query 650 DIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ S++ ++SH ++ + + MV ++++ L ++ G
Sbjct 41 EGMPGTALREISILKKLSHRNIISLVSIIHTDALLTMVFPFIDY-ELKKYIGMNTGKN-- 97
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
M + QL + YL N+VH ++ +NIL+ G+ +K++D G+
Sbjct 98 --IMELVNQLICGVHYLHRMNVVHRDLKPQNILVTSDGV-------LKIADFGLSRSLEI 148
Query 769 R----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE-APLQSRSPSEK 823
R V + + +PE L G+ S +D W G + E+ P +S+
Sbjct 149 RVPPYSSEVVTLWYRSPELLM-GSTSYRFYVDIWSLGCIIYEMITLEPLFPGESKENQLT 207
Query 824 EHFYQRQHRLPEP--------SCPQLATLTSQCLTYEPTQRPSFRTIL 863
+ R + + +CL + QR + I+
Sbjct 208 LIRRKAGTRRSLRGMVEQRLAVPKFVTEIIVRCLDFNYNQRITADEIM 255
>sp|O74536|SNF1_SCHPO SNF1-like protein kinase ssp2 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=ssp2
PE=1 SV=1
Length=576
Score = 221 bits (562), Expect = 3e-60, Method: Composition-based stats.
Identities = 72/278 (26%), Positives = 112/278 (40%), Gaps = 31/278 (11%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK--QEID 949
H LGEG FGKV L T+ T + VA+K + + + +EI
Sbjct 29 RHIGPYIIRETLGEGSFGKVKL----ATHYKTQQKVALKFISRQLLKKSDMHMRVEREIS 84
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQIC 1008
L+ L H HIIK + + +V+EY G L DY+ + + + F QQI
Sbjct 85 YLKLLRHPHIIKLYDVITTPTD--IVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQII 141
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+ Y H +HRDL N+LLD++ VKI DFGL+ + +G+ ++ SP +
Sbjct 142 CAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGN---FLKTSCGSPN-YA 197
Query 1069 APECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + + DVWS G+ LY +L L ++
Sbjct 198 APEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNL-----------FKKVNSC 246
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ PD L++ + R T + +
Sbjct 247 V-----YVMPDFLSPGAQSLIRRMIVADPMQRITIQEI 279
Score = 177 bits (448), Expect = 2e-45, Method: Composition-based stats.
Identities = 58/322 (18%), Positives = 108/322 (34%), Gaps = 43/322 (13%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
QP E +L+ R R L +S + I LG+G+ V
Sbjct 1 MQPQEV-DLMENSTMRNGARVLPPEAISKRHIGPYIIR--ETLGEGSFGKV--------- 48
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTH 669
+ +V LK + D+ + S + + H H
Sbjct 49 ---------------KLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPH 93
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729
+ ++ V + +MV EY G L ++ E+ + QQ+ A+ Y
Sbjct 94 IIKLYDVITTPTDIVMVIEYA-GGELFDYI-VEKKRMTEDEGRRFFQQIICAIEYCHRHK 151
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR---EERVERIPWLAPECLPG 786
+VH ++ N+LL + +K++D G+ + + APE + G
Sbjct 152 IVHRDLKPENLLLD-------DNLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVING 204
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTS 846
+ +D W G L + P+ + + +P+ P +L
Sbjct 205 KLYA-GPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQSLIR 263
Query 847 QCLTYEPTQRPSFRTILRDLTR 868
+ + +P QR + + I RD
Sbjct 264 RMIVADPMQRITIQEIRRDPWF 285
>sp|Q55E58|PATS1_DICDI Probable serine/threonine-protein kinase
pats1 OS=Dictyostelium discoideum OX=44689 GN=pats1 PE=3 SV=1
Length=3184
Score = 231 bits (590), Expect = 3e-60, Method: Composition-based stats.
Identities = 84/294 (29%), Positives = 126/294 (43%), Gaps = 52/294 (18%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG------------PQHRSGWKQEIDI 950
+GEG V + G+ VAVK LK + + +++E +
Sbjct 2253 IGEGGAALVYRARWQ------GQTVAVKKLKTIENLDSPIEINDISLSKAFNEFRRECWV 2306
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQIC 1008
+ L H +I++ KG C D L +V EY+P G+L +L + L A I
Sbjct 2307 MSELEHPNIVQLKGLCLD----PLCIVTEYLPHGNLYSFLHKPEMEFSWLFRLKVALDIS 2362
Query 1009 EGMAYLHAQ--HYIHRDLAARNVLL-----DNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
GMA+LH+ IHRDL + N+LL + + K+ DFGL+ + + G
Sbjct 2363 SGMAFLHSSTPPIIHRDLKSPNILLASINENAQTIAKVVDFGLS------GLQHTITNRG 2416
Query 1062 DSPVFWYAPECL-KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
W APE L K + +DV++FGV L+EL+T D L
Sbjct 2417 VENPLWLAPEILNKTKEASTQTDVYAFGVILWELVTRKDYFGEIGFMTL----------- 2465
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ E + GER P+ CP L+ CW+T+AS RP F + L + E
Sbjct 2466 ---IEEKVINGERPKIPEDCPEMYSKLIVECWQTDASQRPKFSEIEDRLIKIAE 2516
Score = 220 bits (560), Expect = 1e-56, Method: Composition-based stats.
Identities = 67/316 (21%), Positives = 130/316 (41%), Gaps = 23/316 (7%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L +S + ++ ++ +G+G VY R + + + +++ D
Sbjct 2231 DLVMSNFTGAKIPFDQLMIEELIGEGGAALVYRARWQGQTVAVKKLKTIENLDSP----- 2285
Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692
+++ D S F +MS++ H ++ + G+C+ +VTEY+ H
Sbjct 2286 --------IEINDISLSKAFNEFRRECWVMSELEHPNIVQLKGLCLD--PLCIVTEYLPH 2335
Query 693 GPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK--NLVHGNVCGRNILLARLGLAEG 750
G L +L + +++ VA ++S +++L + ++H ++ NILLA + E
Sbjct 2336 GNLYSFLHKPEMEFSWLFRLKVALDISSGMAFLHSSTPPIIHRDLKSPNILLASIN--EN 2393
Query 751 TSPFIKLSDPGV-GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809
K+ D G+ GL VE WLAPE + ST D + FG L E+
Sbjct 2394 AQTIAKVVDFGLSGLQHTITNRGVENPLWLAPE-ILNKTKEASTQTDVYAFGVILWELVT 2452
Query 810 DGEAP--LQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ + + E++ + ++PE + L +C + +QRP F I L
Sbjct 2453 RKDYFGEIGFMTLIEEKVINGERPKIPEDCPEMYSKLIVECWQTDASQRPKFSEIEDRLI 2512
Query 868 RLQPHNLADVLTVNPD 883
++ D+ N
Sbjct 2513 KIAEAMFPDIHLSNIY 2528
>sp|Q8IU85|KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase
type 1D OS=Homo sapiens OX=9606 GN=CAMK1D PE=1 SV=1
Length=385
Score = 215 bits (547), Expect = 3e-60, Method: Composition-based stats.
Identities = 68/269 (25%), Positives = 101/269 (38%), Gaps = 30/269 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG G F +V L TG++ AVK + S + EI +LR + HE+I+
Sbjct 28 TLGTGAFSEVVL----AEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVA 83
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHYI 1020
+ E L LVM+ V G L D + +Q+ + + YLH +
Sbjct 84 LEDIYESPNH--LYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141
Query 1021 HRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
HRDL N+L D + + I DFGL+K +G V + APE L +
Sbjct 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGD----VMSTACGTPGYVAPEVLAQKP 197
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ A D WS GV Y LL + ++L+ P
Sbjct 198 YSKAVDCWSIGVIAYILLCGYPPF--------------YDENDSKLFEQILKAEYEFDSP 243
Query 1138 --DKCPCEVYHLMKNCWETEASFRPTFEN 1164
D ++N E + + R T E
Sbjct 244 YWDDISDSAKDFIRNLMEKDPNKRYTCEQ 272
Score = 148 bits (373), Expect = 3e-37, Method: Composition-based stats.
Identities = 43/314 (14%), Positives = 89/314 (28%), Gaps = 45/314 (14%)
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
+ R S + ++ LG G + V
Sbjct 1 MARENGESSSSWKKQAEDIKKI----FEFKETLGTGAFSEV------------------- 37
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGP 681
V ++ +K + + +++ ++ H ++ + +
Sbjct 38 -----VLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPN 92
Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741
+V + V G L + E+G + +Q+ A+ YL +VH ++ N+L
Sbjct 93 HLYLVMQLVSGGELFDRI-VEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLL 151
Query 742 LARLGLAEGTSPFIKLSDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKW 798
++ I +SD G+ ++APE L S A+D W
Sbjct 152 ----YYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQ--KPYSKAVDCW 205
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQR-----QHRLPEPSCPQLATLTSQCLTYEP 853
G I G P + S+ + + + +P
Sbjct 206 SIGVIAY-ILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264
Query 854 TQRPSFRTILRDLT 867
+R + R
Sbjct 265 NKRYTCEQAARHPW 278
>sp|Q5MAI5|CDKL4_HUMAN Cyclin-dependent kinase-like 4 OS=Homo
sapiens OX=9606 GN=CDKL4 PE=2 SV=2
Length=379
Score = 215 bits (547), Expect = 3e-60, Method: Composition-based stats.
Identities = 67/295 (23%), Positives = 122/295 (41%), Gaps = 34/295 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960
GEG +G V + N +G++VAVK ++++ P + +EI +L+ L H +++
Sbjct 9 KTGEGSYGVV----FKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPNLV 64
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQH 1018
+ + + LV EY +L + L R+ G+A + Q + + + H +
Sbjct 65 NLIEVFRRK--RKMHLVFEYCDH-TLLNELERNPNGVADGVIKSVLWQTLQALNFCHIHN 121
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEYK 1077
IHRD+ N+L+ ++KI DFG A+ + G Y D + ++ APE L + +
Sbjct 122 CIHRDIKPENILITKQGIIKICDFGFAQILIPGDAY----TDYVATRWYRAPELLVGDTQ 177
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE-----RGE 1132
+ + D+W+ G ELLT + I + R + + G
Sbjct 178 YGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNGFFHGI 237
Query 1133 RLPRPDKC-----------PCEVYHLMKNCWETEASFRPTFENLIP--ILKTVHE 1174
+P P+ P + + MK C + R T L+ + E
Sbjct 238 SIPEPEDMETLEEKFSDVHPVAL-NFMKGCLKMNPDDRLTCSQLLESSYFDSFQE 291
Score = 157 bits (396), Expect = 3e-40, Method: Composition-based stats.
Identities = 51/260 (20%), Positives = 93/260 (36%), Gaps = 41/260 (16%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ +L+ G+G+ V++ R + G V +K
Sbjct 1 MEKYEKLAKTGEGSYGVVFKCRNKTSGQ------------------------VVAVKKFV 36
Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
S D + ++ Q+ H +L + V R + +V EY +H L L R
Sbjct 37 ESEDDPVVKKIALREIRMLKQLKHPNLVNLIEVFRRKRKMHLVFEYCDH-TLLNELERNP 95
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
V V Q AL++ N +H ++ NIL+ + G+ IK+ D G
Sbjct 96 NGVADGVIKSVLWQTLQALNFCHIHNCIHRDIKPENILITKQGI-------IKICDFGFA 148
Query 764 ---LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+ + + V + APE L G +++D W G E+ G+ +S
Sbjct 149 QILIPGDAYTDYVATRWYRAPELLV-GDTQYGSSVDIWAIGCVFAELL-TGQPLWPGKSD 206
Query 821 SEKEHFYQR--QHRLPEPSC 838
++ + R +P
Sbjct 207 VDQLYLIIRTLGKLIPRHQS 226
>sp|Q60670|SIK1_MOUSE Serine/threonine-protein kinase SIK1 OS=Mus
musculus OX=10090 GN=Sik1 PE=1 SV=3
Length=779
Score = 225 bits (574), Expect = 3e-60, Method: Composition-based stats.
Identities = 66/273 (24%), Positives = 108/273 (40%), Gaps = 29/273 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTL 954
+ R LG+G+F V L + T VA+K + K + +E+ +++ L
Sbjct 26 FYDVERTLGKGNFAVVKL----ARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLL 81
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAY 1013
H +IIK E + L +V E+ G + DYL + + + QI + Y
Sbjct 82 NHPNIIKLYQVMETKD--MLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVEY 139
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
H H +HRDL N+LLD++ +K+ DFG G + SP + APE
Sbjct 140 CHNHHIVHRDLKTENLLLDSNMDIKLADFGFGNFYKPGEP---LSTWCGSPP-YAAPEVF 195
Query 1074 KEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ ++ DVWS GV LY L+ P + L + + G
Sbjct 196 EGKEYEGPQLDVWSLGVVLYVLVCGSLPFDGP---------------NLPTLRQRVLEG- 239
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
R P + L++ + + R T +
Sbjct 240 RFRIPFFMSQDCETLIRRMLVVDPAKRITIAQI 272
Score = 200 bits (509), Expect = 5e-52, Method: Composition-based stats.
Identities = 67/351 (19%), Positives = 117/351 (33%), Gaps = 40/351 (11%)
Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620
++IM A P Q RV ++ LG+G V R RV
Sbjct 1 MVIMSEFSAVPSGTGQGQQKPLRVGFYDVE--RTLGKGNFAVVKLARHRV---------- 48
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCV 678
+ +V +K++D + D + Y LM ++H ++ ++ V
Sbjct 49 --------------TKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPNIIKLYQVME 94
Query 679 RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGR 738
+VTE+ ++G + +L GH+ Q+ SA+ Y N ++VH ++
Sbjct 95 TKDMLYIVTEFAKNGEMFDYLTSN-GHLSENEARQKFWQILSAVEYCHNHHIVHRDLKTE 153
Query 739 NILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAM 795
N+LL ++ IKL+D G G P+ APE G +
Sbjct 154 NLLLD-------SNMDIKLADFGFGNFYKPGEPLSTWCGSPPYAAPEVFEGKEYE-GPQL 205
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855
D W G L + P+ ++ + + R+P TL + L +P +
Sbjct 206 DVWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCETLIRRMLVVDPAK 265
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906
R + I + L D + G
Sbjct 266 RITIAQIRQHRWMQADPTLLQQDDPAFDMQGYTSNLGDYNEQVLGIMQALG 316
>sp|Q6FKD4|PHO85_CANGA Negative regulator of the PHO system OS=Candida
glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761
/ NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=PHO85 PE=3 SV=1
Length=302
Score = 212 bits (539), Expect = 3e-60, Method: Composition-based stats.
Identities = 66/301 (22%), Positives = 118/301 (39%), Gaps = 36/301 (12%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
K++ LG G + V Y N TG VA+K +K D S +EI ++
Sbjct 1 MSSSQFKQLEKLGNGTYATV----YKGLNKSTGVYVALKEVKLDSEEGTPSTAIREISLM 56
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFA 1004
+ L H++I++ E L LV EY+ L+ Y+ ++G + + F
Sbjct 57 KELKHDNIVRLYDVI--HTENKLTLVFEYMDN-DLKKYMDSRTVGNAPRGLEMNLVKYFQ 113
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
Q+ EG+A+ H +HRDL +N+L+ +K+GDFGLA+A
Sbjct 114 WQLLEGLAFCHENKILHRDLKPQNLLITKRGQLKLGDFGLARAFGIP---VNTFSSEVVT 170
Query 1065 VFWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTK-----FLELIGIA--- 1115
+++ AP+ L + + + D+WS G L E++T + + +G
Sbjct 171 LWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDKMGTPNET 230
Query 1116 ----------QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
RL + L+ + + V L+ + R + +
Sbjct 231 TWPGVTSLPKYNPNFQQRLPKDLKAELQPYVKEPLDDNVIDLLHGLLQLNPDMRLSAKQA 290
Query 1166 I 1166
+
Sbjct 291 L 291
Score = 174 bits (441), Expect = 4e-47, Method: Composition-based stats.
Identities = 49/271 (18%), Positives = 99/271 (37%), Gaps = 43/271 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ + QL LG GT VY+G + G + V LK
Sbjct 1 MSSSQFKQLEKLGNGTYATVYKGLNKSTG------------------------VYVALKE 36
Query 644 LDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+ + SLM ++ H ++ ++ V + +V EY+++ L ++
Sbjct 37 VKLDSEEGTPSTAIREISLMKELKHDNIVRLYDVIHTENKLTLVFEYMDN-DLKKYMDSR 95
Query 703 -----RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ M QL L++ ++H ++ +N+L+ + G +KL
Sbjct 96 TVGNAPRGLEMNLVKYFQWQLLEGLAFCHENKILHRDLKPQNLLITKRGQ-------LKL 148
Query 758 SDPGVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
D G+ + V + + AP+ L G+ + ST++D W G L E+
Sbjct 149 GDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM-GSRTYSTSIDIWSCGCILAEMITGKPL 207
Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQLATL 844
+ + + + + E + P + +L
Sbjct 208 FPGTNDEEQLKLIFDKMGTPNETTWPGVTSL 238
>sp|Q9HGY5|PHO85_CANAX Negative regulator of the PHO system OS=Candida
albicans OX=5476 GN=PHO85 PE=3 SV=1
Length=326
Score = 213 bits (542), Expect = 3e-60, Method: Composition-based stats.
Identities = 67/297 (23%), Positives = 120/297 (40%), Gaps = 30/297 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+++ LGEG + V Y N TG +VA+K + D S +EI
Sbjct 1 MTGSSSQFQQLEKLGEGTYATV----YKGRNRATGALVALKEISLDSEEGTPSTAIREIS 56
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQ 1005
+++ L HE+I+ E L LV EY+ L+ Y+ H + L + F
Sbjct 57 LMKELDHENIVTLYDVI--HTENKLTLVFEYMDK-DLKKYMEVHGQQSALDLKVVKSFMF 113
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
Q+ +G+ + H +HRDL +N+L++N +K+GDFGLA+A + + +
Sbjct 114 QLLKGIMFCHDNRVLHRDLKPQNLLINNKGELKLGDFGLARAFGIP---FNTFSNEVVTL 170
Query 1066 FWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTKFL--------------E 1110
++ AP+ L + + + D+WS G E+ T +
Sbjct 171 WYRAPDVLLGSRAYTTSIDIWSAGCIFAEMCTGKPLFPGTANEDQLIKIFRLMGTPNERT 230
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
GI+Q + + RL P+ + +L+++ + R T +
Sbjct 231 WPGISQYTNYKNNWQIFVPQDLRLIVPNLDSMGL-NLLQSLLQMRPESRITARQALQ 286
Score = 168 bits (426), Expect = 8e-45, Method: Composition-based stats.
Identities = 48/273 (18%), Positives = 99/273 (36%), Gaps = 42/273 (15%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ QL LG+GT VY+GR R G+ V LK +
Sbjct 6 SQFQQLEKLGEGTYATVYKGRNRATGA------------------------LVALKEISL 41
Query 647 SHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL--RRER 703
+ SLM ++ H ++ ++ V + +V EY++ L ++ ++
Sbjct 42 DSEEGTPSTAIREISLMKELDHENIVTLYDVIHTENKLTLVFEYMDK-DLKKYMEVHGQQ 100
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ + QL + + + ++H ++ +N+L+ G +KL D G+
Sbjct 101 SALDLKVVKSFMFQLLKGIMFCHDNRVLHRDLKPQNLLINNKGE-------LKLGDFGLA 153
Query 764 LG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ V + + AP+ L G+ + +T++D W G E+C + +
Sbjct 154 RAFGIPFNTFSNEVVTLWYRAPDVLL-GSRAYTTSIDIWSAGCIFAEMCTGKPLFPGTAN 212
Query 820 PSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLT 850
+ ++ E + P + T
Sbjct 213 EDQLIKIFRLMGTPNERTWPGISQYTNYKNNWQ 245
>sp|Q9FZ59|PEPR2_ARATH Leucine-rich repeat receptor-like protein
kinase PEPR2 OS=Arabidopsis thaliana OX=3702 GN=PEPR2 PE=1
SV=1
Length=1088
Score = 229 bits (583), Expect = 3e-60, Method: Composition-based stats.
Identities = 69/298 (23%), Positives = 122/298 (41%), Gaps = 27/298 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G G V G+GE AVK L + K+EI+ + + H ++I+
Sbjct 800 IGRGAHGVVYRASL-----GSGEEYAVKKLIFAEHIRANQNMKREIETIGLVRHRNLIRL 854
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ 1017
+ + + ++ +Y+P GSL D L R + + + A I G+AYLH
Sbjct 855 ERFWMRKEDG--LMLYQYMPNGSLHDVLHRGNQGEAVLDWSARFNIALGISHGLAYLHHD 912
Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRD+ N+L+D+D IGDFGLA+ + + + APE
Sbjct 913 CHPPIIHRDIKPENILMDSDMEPHIGDFGLARILDDS---TVSTATVTGTTGYIAPENAY 969
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE-----LLE 1129
+ SDV+S+GV L EL+T + + + ++ + ++ + +++
Sbjct 970 KTVRSKESDVYSYGVVLLELVTGKRALDRSFPEDINIVSWVRSVLSSYEDEDDTAGPIVD 1029
Query 1130 RGERLPRPDKCPCE----VYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183
D E V L C + RP+ +++ L + + + SV
Sbjct 1030 PKLVDELLDTKLREQAIQVTDLALRCTDKRPENRPSMRDVVKDLTDLESFVRSTSGSV 1087
Score = 162 bits (411), Expect = 3e-39, Method: Composition-based stats.
Identities = 58/322 (18%), Positives = 104/322 (32%), Gaps = 70/322 (22%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ +G+G VY L G+E V K++
Sbjct 790 ATDNLDDKYIIGRGAHGVVYRASLG-----------------------SGEEYAVK-KLI 825
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ER 703
H + V H +L + +R + +M+ +Y+ +G L L R +
Sbjct 826 FAEHIRANQNMKREIETIGLVRHRNLIRLERFWMRKEDGLMLYQYMPNGSLHDVLHRGNQ 885
Query 704 GHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
G + W + +A ++ L+YL + ++H ++ NIL+ +
Sbjct 886 GEAVLDWSARFNIALGISHGLAYLHHDCHPPIIHRDIKPENILMDSDMEPH-------IG 938
Query 759 DPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
D G+ +S ++APE S D + +G LLE+ G+
Sbjct 939 DFGLARILDDSTVSTATVTGTTGYIAPE--NAYKTVRSKESDVYSYGVVLLELV-TGKRA 995
Query 815 LQSRSPSEKEHFYQRQHRLPEPSCP--------------------------QLATLTSQC 848
L P + + L Q+ L +C
Sbjct 996 LDRSFPEDINIVSWVRSVLSSYEDEDDTAGPIVDPKLVDELLDTKLREQAIQVTDLALRC 1055
Query 849 LTYEPTQRPSFRTILRDLTRLQ 870
P RPS R +++DLT L+
Sbjct 1056 TDKRPENRPSMRDVVKDLTDLE 1077
>sp|O54785|LIMK2_MOUSE LIM domain kinase 2 OS=Mus musculus OX=10090
GN=Limk2 PE=1 SV=2
Length=638
Score = 222 bits (566), Expect = 3e-60, Method: Composition-based stats.
Identities = 79/309 (26%), Positives = 131/309 (42%), Gaps = 38/309 (12%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
S + +F L LG+G FG+ T+ TG+++ +K L C + +
Sbjct 316 RCSSSYSQQIFRPCDLIHGEVLGKGFFGQ----AIKVTHKATGKVMVMKEL-IRCDEETQ 370
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQL 1000
+ E+ ++R+L H +++K+ G +K L L+ EY+ G+L+D+L Q
Sbjct 371 KTFLTEVKVMRSLDHPNVLKFIGVLYK--DKKLNLLTEYIEGGTLKDFLRSVDPFPWQQK 428
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG--------- 1051
+ FA+ I GMAYLH+ IHRDL + N L+ D+ V + DFGL++ + E
Sbjct 429 VRFAKGISSGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRPPVEKA 488
Query 1052 --------HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103
+ R +W APE L + DV+SFG+ L E++ +
Sbjct 489 TTKKRTLRKSDRKKRYTVVGNPYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPD 548
Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163
+ L+ G L + + P CP + L C + E RP F
Sbjct 549 CLPRTLDF-----GLNVKLFWEKFV--------PTDCPPAFFPLAAICCKLEPESRPAFS 595
Query 1164 NLIPILKTV 1172
L + +
Sbjct 596 KLEDSFEAL 604
Score = 198 bits (504), Expect = 4e-52, Method: Composition-based stats.
Identities = 62/345 (18%), Positives = 112/345 (32%), Gaps = 62/345 (18%)
Query 553 PQPGETSNLIIMRGARASPRTLN-LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
P P +++ + +L S S ++ LG+G + +
Sbjct 294 PGPSSPKEPLLLSRDISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKAT 353
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
G +V+K L + F +M + H ++
Sbjct 354 GK------------------------VMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVL 389
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
GV + + ++TEY+E G L +LR P K+ A+ ++S ++YL + ++
Sbjct 390 KFIGVLYKDKKLNLLTEYIEGGTLKDFLRSVD-PFPWQQKVRFAKGISSGMAYLHSMCII 448
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------------------------GAL 767
H ++ N L+ + ++D G+
Sbjct 449 HRDLNSHNCLI-------KLDKTVVVADFGLSRLIVEERKRPPVEKATTKKRTLRKSDRK 501
Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--FDGEAPLQSRSPSEKEH 825
R V W+APE L G S +D + FG L EI + R+ +
Sbjct 502 KRYTVVGNPYWMAPEMLNG--KSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLN 559
Query 826 FY-QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ +P P L + C EP RP+F + L
Sbjct 560 VKLFWEKFVPTDCPPAFFPLAAICCKLEPESRPAFSKLEDSFEAL 604
>sp|Q3U3Q1|ULK3_MOUSE Serine/threonine-protein kinase ULK3 OS=Mus
musculus OX=10090 GN=Ulk3 PE=2 SV=1
Length=472
Score = 218 bits (554), Expect = 3e-60, Method: Composition-based stats.
Identities = 66/282 (23%), Positives = 114/282 (40%), Gaps = 26/282 (9%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWK 945
+ LG G + V T E+VA+K + K
Sbjct 4 PSWGLPRLDGFILTERLGSGTYATVYKAYAK---KDTREVVAIKCVAKKSLNKASVENLL 60
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFA 1004
EI+IL+ + H HI++ K D ++ L+ME+ G L ++ R + +F
Sbjct 61 TEIEILKGIRHPHIVQLKDFQWDND--NIYLIMEFCAGGDLSRFIHTRRILPEKVARVFM 118
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLD--NDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
QQ+ + +LH ++ H DL +N+LL +K+ DFG A+ + E + +R
Sbjct 119 QQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLR---- 174
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
+ APE + ++ D+WS GV LYE L S LE ++
Sbjct 175 GSPLYMAPEMVCRRQYDARVDLWSVGVILYEALFGQPPFASRSFSELE------EKIRSN 228
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
R+ E LP + + L++ E + + R +F++
Sbjct 229 RVIE-------LPLRPQLSLDCRDLLQRLLERDPARRISFKD 263
Score = 192 bits (487), Expect = 2e-51, Method: Composition-based stats.
Identities = 67/293 (23%), Positives = 106/293 (36%), Gaps = 37/293 (13%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
LG GT VY+ + + V K L+ +
Sbjct 14 FILTERLGSGTYATVYKAYAKKDTREVVAIKC------------------VAKKSLNKAS 55
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ ++ + H H+ + ++ E+ G L ++ R +P
Sbjct 56 VEN---LLTEIEILKGIRHPHIVQLKDFQWDNDNIYLIMEFCAGGDLSRFIHTRRI-LPE 111
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
V QQLASAL +L +N+ H ++ +NILL+ L P +KL+D G
Sbjct 112 KVARVFMQQLASALQFLHERNISHLDLKPQNILLSSL-----EKPHLKLADFGFAQHMSP 166
Query 769 -REERV--ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
E+ V ++APE + +D W G L E F G+ P SRS SE E
Sbjct 167 WDEKHVLRGSPLYMAPEMV--CRRQYDARVDLWSVGVILYEALF-GQPPFASRSFSELEE 223
Query 826 FYQRQHRLPEPSCPQLA----TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
+ + P PQL+ L + L +P +R SF+ H
Sbjct 224 KIRSNRVIELPLRPQLSLDCRDLLQRLLERDPARRISFKDFFAHPWVDLEHMP 276
>sp|A5GFW1|AURKA_PIG Aurora kinase A OS=Sus scrofa OX=9823 GN=AURKA
PE=3 SV=1
Length=402
Score = 215 bits (548), Expect = 3e-60, Method: Composition-based stats.
Identities = 68/322 (21%), Positives = 120/322 (37%), Gaps = 32/322 (10%)
Query 851 YEPTQRPSFRTILRDLTRL--QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
P RP T + + +N + S + + R LG+G F
Sbjct 85 PRPVSRPLSNTQQSEQPQPAAPGNNPEKEAASKQKNEESKKRQWALEDFEIGRPLGKGKF 144
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHIIKYKGCC 966
G V L + ++A+K L + ++E++I L H +I++ G
Sbjct 145 GNVYL----AREKQSKFILALKVLFKTQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYF 200
Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
D + L++EY PLG++ L + + + ++ ++Y H++ IHRD+
Sbjct 201 HDAT--RVYLILEYAPLGAVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 258
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
N+LL + +KI DFG + P R + + PE ++ D+W
Sbjct 259 PENLLLGSAGELKIADFGWSVHAPSSR-----RTTLCGTLDYLPPEMIEGRMHDEKVDLW 313
Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
S GV YE L ++ T + + R E PD P
Sbjct 314 SLGVLCYEFLVGKPPFEA---------------NTYQETYKRISRVE-FTFPDFVPEGAR 357
Query 1146 HLMKNCWETEASFRPTFENLIP 1167
L+ + S RPT + ++
Sbjct 358 DLISRLLKHNPSHRPTLKEVLE 379
Score = 183 bits (465), Expect = 4e-49, Method: Composition-based stats.
Identities = 62/348 (18%), Positives = 123/348 (35%), Gaps = 45/348 (13%)
Query 546 SLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605
+ ++ PQP N + A + + + + ++ LG+G NVY
Sbjct 94 NTQQSEQPQPAAPGNNPE-KEAASKQKNEESKKRQW---ALEDFEIGRPLGKGKFGNVYL 149
Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD---IALAFYETASLM 662
R++ + + LKVL + + + +
Sbjct 150 A------------------------REKQSKFILALKVLFKTQLEKAGVEHQLRREVEIQ 185
Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASAL 722
S + H ++ ++G ++ EY G + L++ +LA+AL
Sbjct 186 SHLRHPNILRLYGYFHDATRVYLILEYAPLGAVYRELQKL-SKFDEQRTATYITELANAL 244
Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--REERVERIPWLA 780
SY +K ++H ++ N+LL G++ +K++D G + A S R + +L
Sbjct 245 SYCHSKRVIHRDIKPENLLL-------GSAGELKIADFGWSVHAPSSRRTTLCGTLDYLP 297
Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPSCP 839
PE + G + +D W G E G+ P ++ + E + + P+
Sbjct 298 PEMIEGRMH--DEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRISRVEFTFPDFVPE 354
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
L S+ L + P+ RP+ + +L A S
Sbjct 355 GARDLISRLLKHNPSHRPTLKEVLEHPWITANSKPASSHKKESTSKQP 402
>sp|O42565|LIMK1_XENLA LIM domain kinase 1 OS=Xenopus laevis OX=8355
GN=limk1 PE=2 SV=1
Length=615
Score = 221 bits (564), Expect = 3e-60, Method: Composition-based stats.
Identities = 82/365 (22%), Positives = 144/365 (39%), Gaps = 32/365 (9%)
Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885
H P P A + + P R + + + + +S
Sbjct 243 IEHDPHETPTMPSPC-AEIAVR--RQRPVMRSCSIDRSPGSSCVGSPSCSRRDMSRSESV 299
Query 886 ASD---PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
+ +F L LG G FG+ T+ TGE++ +K L + +
Sbjct 300 RTVTGVHRIFRPSDLIPGEVLGRGCFGQ----AIKVTHRVTGEVMVMKEL-IRFDEETQR 354
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQL 1000
+ +E+ ++R L H H++K+ G +K L + EY+P G+LR + Q
Sbjct 355 TFLKEVKVMRCLEHPHVLKFIGVLYK--DKRLNFITEYIPGGTLRRVIKSMDTHCPWNQR 412
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE- 1059
+ FA+ I GM YLH+ + IHRDL + N L+ D + + +FGL++ +PE R
Sbjct 413 VSFARDIAAGMTYLHSMNIIHRDLNSHNCLVREDGGLVVANFGLSRLIPEETRDLRKDRR 472
Query 1060 ---DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
+W APE + + + DV+SFG+ + E++ ++ + ++
Sbjct 473 KRYTVVGNPYWMAPEMINGRSYDESVDVFSFGIVICEIIGLVNADPDYLPRTMDFG---- 528
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
L + L+R P CP + C + + RP F L L ++
Sbjct 529 -----LNVRAFLDR----FCPPNCPPGFFPSAVLCCDLDPEKRPRFSQLQLWLDSLLRHL 579
Query 1177 QGQAP 1181
Q P
Sbjct 580 NLQLP 584
Score = 198 bits (504), Expect = 2e-52, Method: Composition-based stats.
Identities = 64/343 (19%), Positives = 123/343 (36%), Gaps = 50/343 (15%)
Query 547 LRRCCLPQPGETSNLIIMRGARAS-PRTLNLSQLS-FHRV-DQKEITQLSHLGQGTRTNV 603
+R C + + +S + +R R+ ++ ++ HR+ ++ LG+G
Sbjct 269 MRSCSIDRSPGSSCVGSPSCSRRDMSRSESVRTVTGVHRIFRPSDLIPGEVLGRGCFGQA 328
Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663
+ RV G +V+K L + F + +M
Sbjct 329 IKVTHRVTGE------------------------VMVMKELIRFDEETQRTFLKEVKVMR 364
Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723
+ H H+ GV + +TEY+ G L ++ H P ++ A+ +A+ ++
Sbjct 365 CLEHPHVLKFIGVLYKDKRLNFITEYIPGGTLRRVIKSMDTHCPWNQRVSFARDIAAGMT 424
Query 724 YLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-----------ER 772
YL + N++H ++ N L+ G +++ G+
Sbjct 425 YLHSMNIIHRDLNSHNCLVREDGGLV-------VANFGLSRLIPEETRDLRKDRRKRYTV 477
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI--CFDGEAPLQSRSPSEKEHFYQRQ 830
V W+APE + G S ++D + FG + EI + + R+ +
Sbjct 478 VGNPYWMAPEMING--RSYDESVDVFSFGIVICEIIGLVNADPDYLPRTMDFGLNVRAFL 535
Query 831 HRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
R P+CP C +P +RP F + L L H
Sbjct 536 DRFCPPNCPPGFFPSAVLCCDLDPEKRPRFSQLQLWLDSLLRH 578
>sp|Q9LMP1|WAK2_ARATH Wall-associated receptor kinase 2 OS=Arabidopsis
thaliana OX=3702 GN=WAK2 PE=1 SV=1
Length=732
Score = 224 bits (571), Expect = 4e-60, Method: Composition-based stats.
Identities = 80/364 (22%), Positives = 135/364 (37%), Gaps = 24/364 (7%)
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR------LQPHNLADV 877
E+F Q L + L CL + R + + + +Q + A
Sbjct 325 EYFRWTQIFLGTTIGFSVIMLGISCLQQKIKHRKNTELRQKFFEQNGGGMLIQRVSGAGP 384
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
V+ + R LG+G G V +VA+K +
Sbjct 385 SNVDVKIFTEKGMKEATNGYHESRILGQGGQGTVYKGIL-----PDNSIVAIKKARLGNR 439
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RH 993
Q + E+ +L + H +++K GCC + E L LV E++ G+L D+L
Sbjct 440 SQ-VEQFINEVLVLSQINHRNVVKVLGCCLE-TEVPL-LVYEFINSGTLFDHLHGSLYDS 496
Query 994 SIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
S+ L A ++ +AYLH+ IHRD+ N+LLD + K+ DFG ++ +P
Sbjct 497 SLTWEHRLRIATEVAGSLAYLHSSASIPIIHRDIKTANILLDKNLTAKVADFGASRLIPM 556
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFL 1109
E ++ + + PE SDV+SFGV L ELL+ + P
Sbjct 557 DKE--QLTTIVQGTLGYLDPEYYNTGLLNEKSDVYSFGVVLMELLSGQKALCFERPHCPK 614
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
L+ R E+++ + E + C RP + + L
Sbjct 615 NLVSCFASATKNNRFHEIIDGQVMNEDNQREIQEAARIAAECTRLMGEERPRMKEVAAEL 674
Query 1170 KTVH 1173
+ +
Sbjct 675 EALR 678
Score = 204 bits (518), Expect = 2e-53, Method: Composition-based stats.
Identities = 63/330 (19%), Positives = 120/330 (36%), Gaps = 50/330 (15%)
Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562
RK E + G F + + LQ + + LR+ Q G ++
Sbjct 320 RKVRPEYFRWTQIFLGTTIGFSVIMLGISCLQQKIKHRKNT--ELRQKFFEQNG--GGML 375
Query 563 IMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620
I R + A P +++ + + + LGQG + VY+G L
Sbjct 376 IQRVSGAGPSNVDVKIFTEKGMKEATNGYHESRILGQGGQGTVYKGILPDNSI------- 428
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680
V +K + F ++SQ++H ++ V G C+
Sbjct 429 ------------------VAIKKARLGNRSQVEQFINEVLVLSQINHRNVVKVLGCCLET 470
Query 681 PENIMVTEYVEHGPLDVWLRRE--RGHVPMAWKMVVAQQLASALSYLENK---NLVHGNV 735
++V E++ G L L + ++ +A ++A +L+YL + ++H ++
Sbjct 471 EVPLLVYEFINSGTLFDHLHGSLYDSSLTWEHRLRIATEVAGSLAYLHSSASIPIIHRDI 530
Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANS 790
NILL + + K++D G +E++ + +L PE G
Sbjct 531 KTANILLDK-------NLTAKVADFGASRLIPMDKEQLTTIVQGTLGYLDPEYYNTGL-- 581
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
L+ D + FG L+E+ +A R
Sbjct 582 LNEKSDVYSFGVVLMELLSGQKALCFERPH 611
>sp|P14056|ARAF_RAT Serine/threonine-protein kinase A-Raf OS=Rattus
norvegicus OX=10116 GN=Araf PE=1 SV=1
Length=604
Score = 221 bits (563), Expect = 4e-60, Method: Composition-based stats.
Identities = 75/326 (23%), Positives = 132/326 (40%), Gaps = 27/326 (8%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
+ P + R + + + ++ ++ +G G FG V
Sbjct 266 KSPHSKLPAEQRERKSLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 325
Query 915 CYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
+ VAVK LK A + +K E+ +LR H +I+ + G G
Sbjct 326 RWHG-------DVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG--- 375
Query 974 LQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031
++ ++ SL +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L
Sbjct 376 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 435
Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFG 1088
VKIGDFGLA V + E V W A E ++ + + SDV+++G
Sbjct 436 HEGLTVKIGDFGLA-TVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYG 494
Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148
V LYEL+T ++ + + +G ++ CP + L+
Sbjct 495 VVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSK----------IFSNCPKAMRRLL 544
Query 1149 KNCWETEASFRPTFENLIPILKTVHE 1174
+C + + RP F ++ ++ +
Sbjct 545 TDCLKFQREERPLFPQILATIELLQR 570
Score = 206 bits (523), Expect = 6e-55, Method: Composition-based stats.
Identities = 70/366 (19%), Positives = 122/366 (33%), Gaps = 53/366 (14%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQL-SFHRVDQKEITQLSHLGQGTRTNVYEG 606
+ P E + + + L + V E+ L +G G+ V+ G
Sbjct 266 KSPHSKLPAEQRERKSLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 325
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH--HDIALAFYETASLMSQ 664
R + V +KVL + + A AF ++ +
Sbjct 326 RWHGD---------------------------VAVKVLKVAQPTAEQAQAFKNEMQVLRK 358
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
H ++ G R ++T++ E L L M + VA+Q A + Y
Sbjct 359 TRHVNILLFMGFMTRPG-FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDY 417
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778
L KN++H ++ NI L +K+ D G+ GA E+ + W
Sbjct 418 LHAKNIIHRDLKSNNIFLHEGL-------TVKIGDFGLATVKTRWSGAQPLEQPSGSVLW 470
Query 779 LAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP- 836
+A E + N S D + +G L E+ G P ++ F + L
Sbjct 471 MAAEVIRMQDPNPYSFQSDVYAYGVVLYELM-TGSLPYSHIGSRDQIIFMVGRGYLSPDL 529
Query 837 -----SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
+CP+ + L + CL ++ +RP F IL + LQ + + S
Sbjct 530 SKIFSNCPKAMRRLLTDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQA 589
Query 891 VFHKRY 896
Sbjct 590 DELPAC 595
>sp|P10398|ARAF_HUMAN Serine/threonine-protein kinase A-Raf OS=Homo
sapiens OX=9606 GN=ARAF PE=1 SV=2
Length=606
Score = 221 bits (563), Expect = 4e-60, Method: Composition-based stats.
Identities = 74/326 (23%), Positives = 131/326 (40%), Gaps = 27/326 (8%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
+ P ++ R + + + ++ ++ +G G FG V
Sbjct 268 KSPHSKSPAEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 327
Query 915 CYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
+ VAVK LK + +K E+ +LR H +I+ + G G
Sbjct 328 RWHG-------DVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG--- 377
Query 974 LQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031
++ ++ SL +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L
Sbjct 378 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 437
Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFG 1088
VKIGDFGLA V + E V W A E ++ + + SDV+++G
Sbjct 438 HEGLTVKIGDFGLA-TVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYG 496
Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148
V LYEL+T + + + +G ++ CP + L+
Sbjct 497 VVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSK----------ISSNCPKAMRRLL 546
Query 1149 KNCWETEASFRPTFENLIPILKTVHE 1174
+C + + RP F ++ ++ +
Sbjct 547 SDCLKFQREERPLFPQILATIELLQR 572
Score = 207 bits (528), Expect = 1e-55, Method: Composition-based stats.
Identities = 72/366 (20%), Positives = 122/366 (33%), Gaps = 53/366 (14%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQL-SFHRVDQKEITQLSHLGQGTRTNVYEG 606
+ P E + + + L + V E+ L +G G+ V+ G
Sbjct 268 KSPHSKSPAEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 327
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH--HDIALAFYETASLMSQ 664
R + V +KVL S + A AF ++ +
Sbjct 328 RWHGD---------------------------VAVKVLKVSQPTAEQAQAFKNEMQVLRK 360
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
H ++ G R ++T++ E L L M + VA+Q A + Y
Sbjct 361 TRHVNILLFMGFMTRPG-FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDY 419
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778
L KN++H ++ NI L +K+ D G+ GA E+ + W
Sbjct 420 LHAKNIIHRDLKSNNIFLHEGL-------TVKIGDFGLATVKTRWSGAQPLEQPSGSVLW 472
Query 779 LAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP- 836
+A E + N S D + +G L E+ G P ++ F + L
Sbjct 473 MAAEVIRMQDPNPYSFQSDVYAYGVVLYELM-TGSLPYSHIGCRDQIIFMVGRGYLSPDL 531
Query 837 -----SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
+CP+ + L S CL ++ +RP F IL + LQ + + S
Sbjct 532 SKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQA 591
Query 891 VFHKRY 896
Sbjct 592 DELPAC 597
>sp|D3ZHP7|ULK3_RAT Serine/threonine-protein kinase ULK3 OS=Rattus
norvegicus OX=10116 GN=Ulk3 PE=1 SV=1
Length=472
Score = 218 bits (554), Expect = 4e-60, Method: Composition-based stats.
Identities = 67/280 (24%), Positives = 114/280 (41%), Gaps = 26/280 (9%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQE 947
+ LG G + V T E+VA+K + K E
Sbjct 6 WGLPRLDGFILTERLGSGTYATVYKAYAK---KATREVVAIKCVAKKSLNKASVENLLTE 62
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQ 1006
I+IL+ + H HI++ K D ++ L+ME+ G L ++ R + +F QQ
Sbjct 63 IEILKGIRHPHIVQLKDFQWDND--NIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ 120
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLD--NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+ + +LH ++ H DL +N+LL +K+ DFG A+ + E + +R
Sbjct 121 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLR----GS 176
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+ APE + ++ D+WS GV LYE L S LE ++ R+
Sbjct 177 PLYMAPEMVCRRQYDARVDLWSVGVILYEALFGQPPFASRSFSELE------EKIRSNRV 230
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
E LP + + L++ E + S R +F++
Sbjct 231 IE-------LPLRPQLSLDCRDLLQRLLERDPSHRISFQD 263
Score = 191 bits (486), Expect = 3e-51, Method: Composition-based stats.
Identities = 67/293 (23%), Positives = 105/293 (36%), Gaps = 37/293 (13%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
LG GT VY+ + V K L+ +
Sbjct 14 FILTERLGSGTYATVYKAYAKKATREVVAIKC------------------VAKKSLNKAS 55
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ ++ + H H+ + ++ E+ G L ++ R +P
Sbjct 56 VEN---LLTEIEILKGIRHPHIVQLKDFQWDNDNIYLIMEFCAGGDLSRFIHTRRI-LPE 111
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
V QQLASAL +L +N+ H ++ +NILL+ L P +KL+D G
Sbjct 112 KVARVFMQQLASALQFLHERNISHLDLKPQNILLSSL-----EKPHLKLADFGFAQHMSP 166
Query 769 -REERV--ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
E+ V ++APE + +D W G L E F G+ P SRS SE E
Sbjct 167 WDEKHVLRGSPLYMAPEMV--CRRQYDARVDLWSVGVILYEALF-GQPPFASRSFSELEE 223
Query 826 FYQRQHRLPEPSCPQLA----TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
+ + P PQL+ L + L +P+ R SF+ H
Sbjct 224 KIRSNRVIELPLRPQLSLDCRDLLQRLLERDPSHRISFQDFFAHPWVDLEHMP 276
>sp|P11346|KRAF1_DROME Raf homolog serine/threonine-protein kinase
Raf OS=Drosophila melanogaster OX=7227 GN=Raf PE=1 SV=6
Length=739
Score = 224 bits (571), Expect = 4e-60, Method: Composition-based stats.
Identities = 79/291 (27%), Positives = 124/291 (43%), Gaps = 27/291 (9%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQ 946
+ + +G G FG V + VAVK L P +K
Sbjct 420 ENWNILAEEILIGPRIGSGSFGTVYRAHWHG-------PVAVKTLNVKTPSPAQLQAFKN 472
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFA 1004
E+ +L+ H +I+ + GC + SL +V ++ SL ++ L L+
Sbjct 473 EVAMLKKTRHCNILLFMGCV---SKPSLAIVTQWCEGSSLYKHVHVSETKFKLNTLIDIG 529
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+Q+ +GM YLHA++ IHRDL + N+ L D VKIGDFGLA A +
Sbjct 530 RQVAQGMDYLHAKNIIHRDLKSNNIFLHEDLSVKIGDFGLATA-KTRWSGEKQANQPTGS 588
Query 1065 VFWYAPECLKE---YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
+ W APE ++ + + SDV++FG+ +YELL C K L + +G
Sbjct 589 ILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRG---- 644
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
LL R D P + L ++C + RP F L+ +L+ +
Sbjct 645 -----LLRPDMSQVRSD-APQALKRLAEDCIKYTPKDRPLFRPLLNMLENM 689
Score = 205 bits (522), Expect = 8e-54, Method: Composition-based stats.
Identities = 68/373 (18%), Positives = 116/373 (31%), Gaps = 58/373 (16%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQL----SFHRVDQKEITQLSHLGQGTRTNVYEGRL 608
P N R A S + L L + +EI +G G+ VY
Sbjct 389 PTSTLKHNRPRARSADESNKNLLLRDAKSSEENWNILAEEILIGPRIGSGSFGTVYRAHW 448
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD---PSHHDIALAFYETASLMSQV 665
V +K L+ PS + AF +++ +
Sbjct 449 HGP---------------------------VAVKTLNVKTPSPAQLQ-AFKNEVAMLKKT 480
Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL 725
H ++ G CV P +VT++ E L + + + + +Q+A + YL
Sbjct 481 RHCNILLFMG-CVSKPSLAIVTQWCEGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYL 539
Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL------SREERVERIPWL 779
KN++H ++ NI L +K+ D G+ + I W+
Sbjct 540 HAKNIIHRDLKSNNIFLHE-------DLSVKIGDFGLATAKTRWSGEKQANQPTGSILWM 592
Query 780 APECLPGGA-NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838
APE + N S D + FG + E+ + P S ++ F + L
Sbjct 593 APEVIRMQELNPYSFQSDVYAFGIVMYELLAEC-LPYGHISNKDQILFMVGRGLLRPDMS 651
Query 839 -------PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV 891
L L C+ Y P RP FR +L L + + + +
Sbjct 652 QVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENMLRTLPKIHRSASEPNLTQSQLQ 711
Query 892 FHKRYLKKIRDLG 904
+
Sbjct 712 NDEFLYLPSPKTP 724
>sp|P04627|ARAF_MOUSE Serine/threonine-protein kinase A-Raf OS=Mus
musculus OX=10090 GN=Araf PE=1 SV=2
Length=604
Score = 221 bits (563), Expect = 4e-60, Method: Composition-based stats.
Identities = 75/326 (23%), Positives = 132/326 (40%), Gaps = 27/326 (8%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
+ P + R + + + ++ ++ +G G FG V
Sbjct 266 KSPHSKLPSEQRERKSLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 325
Query 915 CYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
+ VAVK LK A + +K E+ +LR H +I+ + G G
Sbjct 326 RWHG-------DVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG--- 375
Query 974 LQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031
++ ++ SL +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L
Sbjct 376 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 435
Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFG 1088
VKIGDFGLA V + E V W A E ++ + + SDV+++G
Sbjct 436 HEGLTVKIGDFGLA-TVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYG 494
Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148
V LYEL+T ++ + + +G ++ CP + L+
Sbjct 495 VVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSK----------IFSNCPKAMRRLL 544
Query 1149 KNCWETEASFRPTFENLIPILKTVHE 1174
+C + + RP F ++ ++ +
Sbjct 545 TDCLKFQREERPLFPQILATIELLQR 570
Score = 206 bits (524), Expect = 4e-55, Method: Composition-based stats.
Identities = 70/366 (19%), Positives = 122/366 (33%), Gaps = 53/366 (14%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQL-SFHRVDQKEITQLSHLGQGTRTNVYEG 606
+ P E + + + L + V E+ L +G G+ V+ G
Sbjct 266 KSPHSKLPSEQRERKSLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 325
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH--HDIALAFYETASLMSQ 664
R + V +KVL + + A AF ++ +
Sbjct 326 RWHGD---------------------------VAVKVLKVAQPTAEQAQAFKNEMQVLRK 358
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
H ++ G R ++T++ E L L M + VA+Q A + Y
Sbjct 359 TRHVNILLFMGFMTRPG-FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDY 417
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778
L KN++H ++ NI L +K+ D G+ GA E+ + W
Sbjct 418 LHAKNIIHRDLKSNNIFLHEGL-------TVKIGDFGLATVKTRWSGAQPLEQPSGSVLW 470
Query 779 LAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP- 836
+A E + N S D + +G L E+ G P ++ F + L
Sbjct 471 MAAEVIRMQDPNPYSFQSDVYAYGVVLYELM-TGSLPYSHIGSRDQIIFMVGRGYLSPDL 529
Query 837 -----SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890
+CP+ + L + CL ++ +RP F IL + LQ + + S
Sbjct 530 SKIFSNCPKAMRRLLTDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQA 589
Query 891 VFHKRY 896
Sbjct 590 DELPAC 595
>sp|O08678|MARK1_RAT Serine/threonine-protein kinase MARK1 OS=Rattus
norvegicus OX=10116 GN=Mark1 PE=1 SV=1
Length=793
Score = 225 bits (573), Expect = 4e-60, Method: Composition-based stats.
Identities = 70/248 (28%), Positives = 109/248 (44%), Gaps = 13/248 (5%)
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
+ + + ++ ++ H + + +G+G+F KV L + TG
Sbjct 28 HIPPTKSSSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKL----ARHVLTG 83
Query 925 EMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983
VAVK + K P +E+ I++ L H +I+K E EK+L LVMEY
Sbjct 84 REVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIE--TEKTLYLVMEYASG 141
Query 984 GSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
G + DYL H + + +QI + Y H + +HRDL A N+LLD D +KI DF
Sbjct 142 GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADF 201
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSS 1101
G + G++ + + APE + K+ DVWS GV LY L++
Sbjct 202 GFSNEFTVGNKL----DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF 257
Query 1102 QSPPTKFL 1109
K L
Sbjct 258 DGQNLKEL 265
Score = 181 bits (458), Expect = 2e-45, Method: Composition-based stats.
Identities = 53/287 (18%), Positives = 93/287 (32%), Gaps = 40/287 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+G+G V R + G V +K++D +
Sbjct 59 NYRLQKTIGKGNFAKVKLARHVLTGR------------------------EVAVKIIDKT 94
Query 648 HHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ + +M ++H ++ + V +V EY G + +L G
Sbjct 95 QLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAH-GR 153
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+ +Q+ SA+ Y K +VH ++ N+LL IK++D G
Sbjct 154 MKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLD-------ADMNIKIADFGFSNE 206
Query 766 AL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ P+ APE G +D W G L + G P ++ E
Sbjct 207 FTVGNKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKE 264
Query 823 KEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
R +R+P L + L P +R S I++D
Sbjct 265 LRERVLRGKYRVPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWM 311
>sp|Q5N942|SAPK4_ORYSJ Serine/threonine-protein kinase SAPK4 OS=Oryza
sativa subsp. japonica OX=39947 GN=SAPK4 PE=2 SV=2
Length=360
Score = 214 bits (544), Expect = 4e-60, Method: Composition-based stats.
Identities = 73/276 (26%), Positives = 113/276 (41%), Gaps = 26/276 (9%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+ +RD+G G+FG L N T E+VAVK + + G + +EI R+
Sbjct 1 MEKYEAVRDIGSGNFGVARLM----RNRETRELVAVKCI--ERGHRIDENVYREIINHRS 54
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012
L H +II++K L +VME+ G L D + R + F QQ+ G++
Sbjct 55 LRHPNIIRFKEVILTPTH--LMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVS 112
Query 1013 YLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
Y H HRDL NVLLD +KI DFG +K + R + +P + AP
Sbjct 113 YCHHMQICHRDLKLENVLLDGSPAPRLKICDFGYSK---SSVLHSRPKSAVGTPA-YIAP 168
Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E L ++ +DVWS GVTLY +L + I + ++ + +
Sbjct 169 EVLSRREYDGKLADVWSCGVTLYVMLVGAYPFEDQDDPKNIRKTIQRIMSVQYKIPDYV- 227
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
E L+ + R T + +
Sbjct 228 ---------HISAECKQLIARIFVNNPLRRITMKEI 254
Score = 161 bits (407), Expect = 6e-42, Method: Composition-based stats.
Identities = 48/268 (18%), Positives = 87/268 (32%), Gaps = 17/268 (6%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
R+R V +K ++ H I Y + H ++ V + ++V E+
Sbjct 22 RNRETRELVAVKCIERGHR-IDENVYREIINHRSLRHPNIIRFKEVILTPTHLMIVMEFA 80
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L + +RG QQL +SY + + H ++ N+LL
Sbjct 81 AGGELFDRI-CDRGRFSEDEARYFFQQLICGVSYCHHMQICHRDLKLENVLLD-----GS 134
Query 751 TSPFIKLSDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+P +K+ D G ++ + V ++APE L D W G TL +
Sbjct 135 PAPRLKICDFGYSKSSVLHSRPKSAVGTPAYIAPEVLSRREYD-GKLADVWSCGVTLYVM 193
Query 808 CFDGEAPLQSRSPSEKEH----FYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRT 861
P Q+++P+ + L ++ P +R + +
Sbjct 194 LVGAYPFEDQDDPKNIRKTIQRIMSVQYKIPDYVHISAECKQLIARIFVNNPLRRITMKE 253
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDP 889
I L+ T D
Sbjct 254 IKSHPWFLKNLPRELTETAQAMYYRRDN 281
>sp|O65924|Y2921_ARATH Putative leucine-rich repeat receptor-like
protein kinase At2g19210 OS=Arabidopsis thaliana OX=3702
GN=At2g19210 PE=1 SV=1
Length=881
Score = 226 bits (577), Expect = 4e-60, Method: Composition-based stats.
Identities = 61/295 (21%), Positives = 121/295 (41%), Gaps = 18/295 (6%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
+ K R LG+G FGKV + VAVK L ++ Q +
Sbjct 564 RYYKYSEVVKVTNNFERVLGQGGFGKVYHGVL------NDDQVAVKIL-SESSAQGYKEF 616
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLL 1001
+ E+++L ++H+++ G C + K + L+ E++ G+L DYL + + + L
Sbjct 617 RAEVELLLRVHHKNLTALIGYCHEG--KKMALIYEFMANGTLGDYLSGEKSYVLSWEERL 674
Query 1002 LFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
+ +G+ YLH + RD+ N+L++ KI DFGL+++V
Sbjct 675 QISLDAAQGLEYLHNGCKPPIVQRDVKPANILINEKLQAKIADFGLSRSVALDGNNQDT- 733
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQ 1116
+ + PE K SD++SFGV L E+++ + + + +
Sbjct 734 TAVAGTIGYLDPEYHLTQKLSEKSDIYSFGVVLLEVVSGQPVIARSRTTAENIHITDRVD 793
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
++ + +++ ++ + C + + RPT +++ LK
Sbjct 794 LMLSTGDIRGIVDPKLGERFDAGSAWKITEVAMACASSSSKNRPTMSHVVAELKE 848
Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats.
Identities = 61/274 (22%), Positives = 97/274 (35%), Gaps = 45/274 (16%)
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
G RA P + V + LGQG VY G L +
Sbjct 553 GVRAGPLDTTKRYYKYSEVVKVTNNFERVLGQGGFGKVYHGVLNDD-------------- 598
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
+V +K+L S F L+ +V H +L + G C G + +
Sbjct 599 ------------QVAVKILSESSAQGYKEFRAEVELLLRVHHKNLTALIGYCHEGKKMAL 646
Query 686 VTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNIL 741
+ E++ +G L +L E+ + + ++ ++ A L YL N +V +V NIL
Sbjct 647 IYEFMANGTLGDYLSGEKSYVLSWEERLQISLDAAQGLEYLHNGCKPPIVQRDVKPANIL 706
Query 742 LARLGLAEGTSPFIKLSDPGVGLGA------LSREERVERIPWLAPECLPGGANSLSTAM 795
+ A K++D G+ I +L PE LS
Sbjct 707 INEKLQA-------KIADFGLSRSVALDGNNQDTTAVAGTIGYLDPEY--HLTQKLSEKS 757
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
D + FG LLE+ +SR+ +E H R
Sbjct 758 DIYSFGVVLLEVVSGQPVIARSRTTAENIHITDR 791
>sp|Q61036|PAK3_MOUSE Serine/threonine-protein kinase PAK 3 OS=Mus
musculus OX=10090 GN=Pak3 PE=1 SV=2
Length=559
Score = 220 bits (560), Expect = 4e-60, Method: Composition-based stats.
Identities = 62/275 (23%), Positives = 108/275 (39%), Gaps = 23/275 (8%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
K+ + +G+G G V Y + TG+ VA+K + P+ + EI ++R
Sbjct 279 PKKKYTRFEKIGQGASGTV----YTALDIATGQEVAIKQMNLQQQPK-KELIINEILVMR 333
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
+ +I+ Y E L +VMEY+ GSL D + + Q+ ++ + +
Sbjct 334 ENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALD 391
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+LH+ IHRD+ + N+LL D VK+ DFG + R +W APE
Sbjct 392 FLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEV 448
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + D+WS G+ E++ PP + T
Sbjct 449 VTRKAYGPKVDIWSLGIMAIEMV-----EGEPPYLNENPLRALYLIATNGT--------P 495
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L P++ + C E + R + + L+
Sbjct 496 ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQ 530
Score = 178 bits (452), Expect = 5e-46, Method: Composition-based stats.
Identities = 59/333 (18%), Positives = 107/333 (32%), Gaps = 56/333 (17%)
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRV------------DQKEITQLSHLGQGTRTN 602
P N R + R S+++ + +K+ T+ +GQG
Sbjct 237 PPSAENANSTTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGT 296
Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662
VY D V +K ++ +M
Sbjct 297 VY------------------------TALDIATGQEVAIKQMNLQQQPKKELIINEILVM 332
Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASAL 722
+ + ++ + G E +V EY+ G L + + V ++ AL
Sbjct 333 RENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TETCMDEGQIAAVCRECLQAL 390
Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREERVERIPW 778
+L + ++H ++ NILL G +KL+D G R V W
Sbjct 391 DFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW 443
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL----P 834
+APE + A +D W G +E+ +GE P + +P + P
Sbjct 444 MAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNGTPELQNP 500
Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
E ++CL + +R S + +L+
Sbjct 501 ERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPF 533
>sp|Q39030|KPK2_ARATH Serine/threonine-protein kinase AtPK2/AtPK19
OS=Arabidopsis thaliana OX=3702 GN=ATPK2 PE=1 SV=2
Length=471
Score = 217 bits (553), Expect = 4e-60, Method: Composition-based stats.
Identities = 71/281 (25%), Positives = 117/281 (42%), Gaps = 37/281 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960
+G+G FGKV Y T E+ A+K ++ D H K E DIL + H I+
Sbjct 146 VGQGAFGKV----YQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDHPFIV 201
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHY 1019
+ K Q + L LV++++ G L L + ++ +I +++LH +
Sbjct 202 QLKYSF--QTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGI 259
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDL N+L+D D V + DFGLAK E + + APE ++
Sbjct 260 MHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSNSM----CGTTEYMAPEIVRGKGHD 315
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
A+D WS G+ LYE+LT K + ++++ +L P
Sbjct 316 KAADWWSVGILLYEMLTGKPPFLGSKGKIQQ---------------KIVKDKIKL--PQF 358
Query 1140 CPCEVYHLMKNCWETEASFR----PT-FENL--IPILKTVH 1173
E + L+K + E R P+ E + K ++
Sbjct 359 LSNEAHALLKGLLQKEPERRLGSGPSGAEEIKKHKWFKAIN 399
Score = 161 bits (407), Expect = 7e-41, Method: Composition-based stats.
Identities = 52/276 (19%), Positives = 105/276 (38%), Gaps = 35/276 (13%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V ++ L +GQG VY ++R + + + K+ +D K+
Sbjct 135 VGIEDFEVLKVVGQGAFGKVY--QVRKKDTSEIYAMKVMRKD----------------KI 176
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
++ +H + A +++++ H + + +V +++ G L L +
Sbjct 177 VEKNHAEYMKA---ERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQ- 232
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
G V ++ SA+S+L K ++H ++ NIL+ G + L+D G+
Sbjct 233 GLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDVDG-------HVMLTDFGLA 285
Query 764 LGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
++APE + G + A D W G L E+ G+ P
Sbjct 286 KEFEENTRSNSMCGTTEYMAPEIVRGKGH--DKAADWWSVGILLYEML-TGKPPFLGSKG 342
Query 821 SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
++ + + +LP+ + L L EP +R
Sbjct 343 KIQQKIVKDKIKLPQFLSNEAHALLKGLLQKEPERR 378
>sp|Q94C40|CIPKH_ARATH CBL-interacting serine/threonine-protein
kinase 17 OS=Arabidopsis thaliana OX=3702 GN=CIPK17 PE=1 SV=1
Length=432
Score = 216 bits (550), Expect = 4e-60, Method: Composition-based stats.
Identities = 70/262 (27%), Positives = 110/262 (42%), Gaps = 27/262 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW--KQEIDILRTLYHEHI 959
LGEG+ KV + TGE A+K ++ C + + K+EI L+ L H +I
Sbjct 16 TLGEGNSAKVKF----AIDTLTGESFAIKIIEKSCITRLNVSFQIKREIRTLKVLKHPNI 71
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
++ + + + +V+E V G L D + + + Q QQ+ +G++Y H +
Sbjct 72 VRLHEVLASKTK--IYMVLECVTGGDLFDRIVSKGKLSETQGRKMFQQLIDGVSYCHNKG 129
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL NVLLD +KI DFGL+ E + SP + APE L +
Sbjct 130 VFHRDLKLENVLLDAKGHIKITDFGLSALSQHYREDGLLHTTCGSPN-YVAPEVLANEGY 188
Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
ASD+WS GV LY +LT C + + + +G+ P P
Sbjct 189 DGAASDIWSCGVILYVILTGCLPFDDA---------------NLAVICRKIFKGD-PPIP 232
Query 1138 DKCPCEVYHLMKNCWETEASFR 1159
++K + R
Sbjct 233 RWISLGAKTMIKRMLDPNPVTR 254
Score = 162 bits (410), Expect = 1e-41, Method: Composition-based stats.
Identities = 54/304 (18%), Positives = 96/304 (32%), Gaps = 19/304 (6%)
Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYET 658
V +G RV + + D +K+++ S +++
Sbjct 1 MVIKGM-RVGKYELGRTLGEGNSAKVKFAIDTLTGESFAIKIIEKSCITRLNVSFQIKRE 59
Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQL 718
+ + H ++ +H V + MV E V G L + +G + + QQL
Sbjct 60 IRTLKVLKHPNIVRLHEVLASKTKIYMVLECVTGGDLFDRI-VSKGKLSETQGRKMFQQL 118
Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV-GLGALSRE-----ER 772
+SY NK + H ++ N+LL G IK++D G+ L RE
Sbjct 119 IDGVSYCHNKGVFHRDLKLENVLLDAKG-------HIKITDFGLSALSQHYREDGLLHTT 171
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832
++APE L A D W G L I + ++
Sbjct 172 CGSPNYVAPEVLANEGYD-GAASDIWSCGVILYVILTGCLPFDDANLAVICRKIFKGDPP 230
Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVF 892
+P T+ + L P R + I + ++ + +
Sbjct 231 IPRWISLGAKTMIKRMLDPNPVTRVTIAGIKAHDWFKHDYTPSNYDDDDDVYLIQEDVFM 290
Query 893 HKRY 896
K Y
Sbjct 291 MKEY 294
>sp|P93604|LRK10_WHEAT Rust resistance kinase Lr10 OS=Triticum
aestivum OX=4565 GN=LRK10 PE=2 SV=1
Length=636
Score = 222 bits (565), Expect = 4e-60, Method: Composition-based stats.
Identities = 70/330 (21%), Positives = 122/330 (37%), Gaps = 23/330 (7%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
+ + K + +G+G FG V G VA
Sbjct 311 HMKVEMFLKTYGTSKPTRYTFSEVKKMARRFKEKVGQGGFGSVYKGEL-----PNGVPVA 365
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
VK L+ G + E+ + ++H +I++ G C + ++ L+ E++P SL
Sbjct 366 VKMLENSTGEG--ESFINEVATIGLIHHANIVRLLGFCSEGMRRA--LIYEFMPNESLEK 421
Query 989 YLP-------RHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVK 1038
Y+ ++ + +LL A I GM YLH Q +H D+ N+LLD + K
Sbjct 422 YIFSDDSNIFQNLLVPEKLLDIALGIARGMEYLHQGCNQRILHFDIKPHNILLDYNFNPK 481
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE--YKFYYASDVWSFGVTLYELLT 1096
I DFGLAK + + + APE Y +DV+SFG+ + E+++
Sbjct 482 ISDFGLAKLCARDQSIVTL-TAARGTMGYIAPELYSRNFGGVSYKADVYSFGMLVLEMVS 540
Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156
+S ++ V+ EL E ++ + C +
Sbjct 541 GRRNSDPRIGSQDDVYLPEWIYEKVINGEELALTLETTQEEKDKVRQLAMVALWCIQWNP 600
Query 1157 SFRPTFENLIPILK-TVHEKYQGQAPSVFS 1185
RP+ ++ +L + P V S
Sbjct 601 RNRPSMTKVVNMLTGRLQSLQMPPKPFVSS 630
Score = 204 bits (518), Expect = 5e-54, Method: Composition-based stats.
Identities = 52/316 (16%), Positives = 110/316 (35%), Gaps = 63/316 (20%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
+F V + +GQG +VY+G L + V
Sbjct 330 TFSEVKKMARRFKEKVGQGGFGSVYKGELPNG-------------------------VPV 364
Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+K+L+ S + +F + + + H ++ + G C G ++ E++ + L+ ++
Sbjct 365 AVKMLENSTGEG-ESFINEVATIGLIHHANIVRLLGFCSEGMRRALIYEFMPNESLEKYI 423
Query 700 RRERGH-----VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGT 751
+ + + + +A +A + YL N+ ++H ++ NILL
Sbjct 424 FSDDSNIFQNLLVPEKLLDIALGIARGMEYLHQGCNQRILHFDIKPHNILLD-------Y 476
Query 752 SPFIKLSDPGVGLGALSREERV------ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ K+SD G+ + V + ++APE +S D + FG +L
Sbjct 477 NFNPKISDFGLAKLCARDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKADVYSFGMLVL 536
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRL----------------PEPSCPQLATLTSQCL 849
E+ + + + + + QLA + C+
Sbjct 537 EMVSGRRNSDPRIGSQDDVYLPEWIYEKVINGEELALTLETTQEEKDKVRQLAMVALWCI 596
Query 850 TYEPTQRPSFRTILRD 865
+ P RPS ++
Sbjct 597 QWNPRNRPSMTKVVNM 612
>sp|Q6YY75|NEK6_ORYSJ Serine/threonine-protein kinase Nek6 OS=Oryza
sativa subsp. japonica OX=39947 GN=NEK6 PE=1 SV=2
Length=534
Score = 219 bits (558), Expect = 4e-60, Method: Composition-based stats.
Identities = 60/299 (20%), Positives = 118/299 (39%), Gaps = 31/299 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILR 952
+ + +G G +G L + +K ++ + + + QE+ ++
Sbjct 1 MEQYEVVEQIGRGAYGSAYLVVHKGERKR----YVMKKIRLSKQNDKFQRTAYQEMSLMA 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICE 1009
+L + +I++YK D+G + +V Y G + + + + ++ + Q+
Sbjct 57 SLSNPYIVEYKDGWVDEGTSA-CIVTSYCEGGDMAERIKKARGVLFSEERVCRWFTQLLL 115
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ YLH +HRDL N+LL D +++ DFGLAK + E + +
Sbjct 116 ALDYLHCNRVLHRDLKCSNILLTKDNNIRLADFGLAKLLMED-----LASTIVGTPNYMC 170
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE L + + Y SD+WS G ++E+L H + ++ + L +
Sbjct 171 PEILADIPYGYKSDIWSLGCCMFEILAHRPAFKAA---------------DMASLINKIN 215
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAPSVFSV 1186
R P P + ++K+ RPT L+ P L+ + +P V
Sbjct 216 RSSISPMPPIYSSSLKQIVKSMLRKNPEHRPTAGELLRHPYLQPYLAESCSCSPIYLPV 274
Score = 155 bits (393), Expect = 1e-38, Method: Composition-based stats.
Identities = 55/303 (18%), Positives = 98/303 (32%), Gaps = 38/303 (13%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VL 644
++ + +G+G + Y + E ++ V+ K L
Sbjct 1 MEQYEVVEQIGRGAYGSAYLVVHKGE-----------------------RKRYVMKKIRL 37
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVH-GVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ Y+ SLM+ +S+ ++ G G +VT Y E G + +++ R
Sbjct 38 SKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSACIVTSYCEGGDMAERIKKAR 97
Query 704 GHV-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
G + QL AL YL ++H ++ NILL + I+L+D G+
Sbjct 98 GVLFSEERVCRWFTQLLLALDYLHCNRVLHRDLKCSNILLTKDN-------NIRLADFGL 150
Query 763 GLGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+ V ++ PE L D W G + EI A +
Sbjct 151 AKLLMEDLASTIVGTPNYMCPEILADIPYGY--KSDIWSLGCCMFEILAHRPAFKAADMA 208
Query 821 SEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
S + +P L + L P RP+ +LR + +
Sbjct 209 SLINKINRSSISPMPPIYSSSLKQIVKSMLRKNPEHRPTAGELLRHPYLQPYLAESCSCS 268
Query 880 VNP 882
Sbjct 269 PIY 271
>sp|Q924U5|TESK2_RAT Dual specificity testis-specific protein
kinase 2 OS=Rattus norvegicus OX=10116 GN=Tesk2 PE=2 SV=1
Length=570
Score = 220 bits (560), Expect = 4e-60, Method: Composition-based stats.
Identities = 72/286 (25%), Positives = 126/286 (44%), Gaps = 33/286 (12%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G G F +V + + +G+++A+K + +R+ +E+ ++ L H
Sbjct 59 FTREKIGSGFFSEV----FKVRHRASGQVMALKM---NTLSSNRANLLKEMQLMNRLSHP 111
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHA 1016
+I+++ G C QG+ L + EY+ G+L L + + + A I G++YLH
Sbjct 112 NILRFMGVCVHQGQ--LHALTEYINSGNLEQLLDSNLYLPWTVRVKLAYDIAVGLSYLHF 169
Query 1017 QHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ HRDL ++N L+ D + DFGLA+ +P+ SP FW APE L
Sbjct 170 KGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGSEKLAVVGSP-FWMAPEVL 228
Query 1074 KEYKFYYASDVWSFGVTLYELLTH--CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
++ + +DV+S+G+ L E++ D P T+ L A M
Sbjct 229 RDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVG---------- 278
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
CP + L NC + RP+FE + L+ + + Q
Sbjct 279 -------DCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLEEIMSRLQ 317
Score = 192 bits (487), Expect = 2e-50, Method: Composition-based stats.
Identities = 65/314 (21%), Positives = 116/314 (37%), Gaps = 40/314 (13%)
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
++ R S + +F R+ + +G G + V++ R R
Sbjct 33 VQVGRVSSSSYRAIISAFSRLTSLDDFTREKIGSGFFSEVFKVRHRA------------- 79
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
GQ + + + L + ++ + LM+++SH ++ GVCV +
Sbjct 80 ---------SGQVMALKMNTLSSNRANL----LKEMQLMNRLSHPNILRFMGVCVHQGQL 126
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+TEY+ G L+ L ++P ++ +A +A LSYL K + H ++ +N L+
Sbjct 127 HALTEYINSGNLEQLL-DSNLYLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIK 185
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDK 797
R + ++D G+ V W+APE L + D
Sbjct 186 R----DENGYSAVVADFGLAEKIPDASIGSEKLAVVGSPFWMAPEVLRD--EPYNEKADV 239
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQR 856
+ +G L EI +A +E + CP LT C +P R
Sbjct 240 FSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPSDFLQLTFNCCNMDPKLR 299
Query 857 PSFRTILRDLTRLQ 870
PSF I + L +
Sbjct 300 PSFEEIGKTLEEIM 313
>sp|Q2WFL5|HOG1_COCMI Mitogen-activated protein kinase HOG1 OS=Cochliobolus
miyabeanus OX=101162 GN=HOG1 PE=3 SV=1
Length=354
Score = 213 bits (543), Expect = 4e-60, Method: Composition-based stats.
Identities = 67/274 (24%), Positives = 107/274 (39%), Gaps = 29/274 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V + T + VAVK + K P +E+ +L+ L HE+II
Sbjct 26 VGMGAFGLVC----SAKDQLTNQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENIIS 81
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
E + V E + L L + + F QI G+ Y+H+ +H
Sbjct 82 LSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVH 139
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKFYY 1080
RDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 140 RDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKYDV 193
Query 1081 ASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTELL 1128
D+WS G E+L + + EL+G + LR + L
Sbjct 194 EVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVQSL 253
Query 1129 ERGERLP---RPDKCPCEVYHLMKNCWETEASFR 1159
+ ER P + + L++N + R
Sbjct 254 PKRERQPLANKFKNAEPDAVDLLENMLVFDPRKR 287
Score = 134 bits (337), Expect = 8e-33, Method: Composition-based stats.
Identities = 35/231 (15%), Positives = 74/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + +D+ V +K ++ P ++ Y
Sbjct 10 FGTTFEITSRYTDLQLVGMGAF---GLVCSAKDQLTNQAVAVKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q9R1U5|SIK1_RAT Serine/threonine-protein kinase SIK1 OS=Rattus
norvegicus OX=10116 GN=Sik1 PE=1 SV=1
Length=776
Score = 224 bits (572), Expect = 4e-60, Method: Composition-based stats.
Identities = 65/273 (24%), Positives = 107/273 (39%), Gaps = 29/273 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTL 954
+ R LG+G+F V L + T VA+K + K + +E+ +++ L
Sbjct 26 FYDVERTLGKGNFAVVKL----ARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLL 81
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAY 1013
H +IIK E + L +V E+ G + DYL + + + QI + Y
Sbjct 82 NHPNIIKLYQVMETKD--MLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEY 139
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
H H +HRDL N+LLD + +K+ DFG G + SP + APE
Sbjct 140 CHNHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKPGEP---LSTWCGSPP-YAAPEVF 195
Query 1074 KEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ ++ D+WS GV LY L+ P + L + + G
Sbjct 196 EGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGP---------------NLPTLRQRVLEG- 239
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
R P + L++ + + R T +
Sbjct 240 RFRIPFFMSQDCETLIRRMLVVDPAKRITIAQI 272
Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats.
Identities = 66/351 (19%), Positives = 115/351 (33%), Gaps = 40/351 (11%)
Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620
++IM A P Q RV ++ LG+G V R RV
Sbjct 1 MVIMSEFSAVPTGTGQGQQKPLRVGFYDVE--RTLGKGNFAVVKLARHRV---------- 48
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCV 678
+ +V +K++D + D + Y LM ++H ++ ++ V
Sbjct 49 --------------TKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPNIIKLYQVME 94
Query 679 RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGR 738
+VTE+ ++G + +L GH+ Q+ SA+ Y N ++VH ++
Sbjct 95 TKDMLYIVTEFAKNGEMFDYLTSN-GHLSENEARKKFWQILSAVEYCHNHHIVHRDLKTE 153
Query 739 NILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAM 795
N+LL + IKL+D G G P+ APE G +
Sbjct 154 NLLLD-------GNMDIKLADFGFGNFYKPGEPLSTWCGSPPYAAPEVFEGKEYE-GPQL 205
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855
D W G L + P+ ++ + + R+P TL + L +P +
Sbjct 206 DIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCETLIRRMLVVDPAK 265
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906
R + I + L + G
Sbjct 266 RITIAQIRQHRWMQADPTLLQQDDPAFSMQGYTSNLGDYNEQVLGIMQALG 316
>sp|Q9VXE5|PAKM_DROME Serine/threonine-protein kinase PAK mbt
OS=Drosophila melanogaster OX=7227 GN=mbt PE=1 SV=2
Length=639
Score = 222 bits (565), Expect = 4e-60, Method: Composition-based stats.
Identities = 64/268 (24%), Positives = 111/268 (41%), Gaps = 23/268 (9%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+GEG G V + T+ TG VAVK + Q R E+ I+R +H +
Sbjct 370 HFNKIGEGSTGTVCI----ATDKSTGRQVAVKKMDLRK-QQRRELLFNEVVIMRDYHHPN 424
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
I++ E L +VMEY+ G+L D + + Q+ +Q + +AYLH+Q
Sbjct 425 IVETYSSFLVNDE--LWVVMEYLEGGALTDIVTHSRMDEEQIATVCKQCLKALAYLHSQG 482
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRD+ + ++LL D VK+ DFG V + R+ +W +PE + +
Sbjct 483 VIHRDIKSDSILLAADGRVKLSDFGFCAQVSQELP---KRKSLVGTPYWMSPEVISRLPY 539
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
D+WS G+ + E++ + P + R+ ++ + L
Sbjct 540 GPEVDIWSLGIMVIEMVDGEPPFFNEP-----------PLQAMRRIRDM--QPPNLKNAH 586
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLI 1166
K + + + + R T L+
Sbjct 587 KVSPRLQSFLDRMLVRDPAQRATAAELL 614
Score = 186 bits (472), Expect = 5e-48, Method: Composition-based stats.
Identities = 55/291 (19%), Positives = 103/291 (35%), Gaps = 44/291 (15%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
++ + + +G+G+ V D+ +V +K +
Sbjct 364 PRENLDHFNKIGEGSTGTVC------------------------IATDKSTGRQVAVKKM 399
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D + +M H ++ + + E +V EY+E G L + R
Sbjct 400 DLRKQQRRELLFNEVVIMRDYHHPNIVETYSSFLVNDELWVVMEYLEGGALTDIVTHSR- 458
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV-- 762
+ V +Q AL+YL ++ ++H ++ +ILLA G +KLSD G
Sbjct 459 -MDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLAADGR-------VKLSDFGFCA 510
Query 763 --GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
R+ V W++PE + +D W G ++E+ DGE P + P
Sbjct 511 QVSQELPKRKSLVGTPYWMSPEVIS--RLPYGPEVDIWSLGIMVIEMV-DGEPPFFNEPP 567
Query 821 SEKE----HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ + P+L + + L +P QR + +L
Sbjct 568 LQAMRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAAELLAHPF 618
>sp|Q8VHJ5|MARK1_MOUSE Serine/threonine-protein kinase MARK1 OS=Mus
musculus OX=10090 GN=Mark1 PE=1 SV=2
Length=795
Score = 225 bits (573), Expect = 4e-60, Method: Composition-based stats.
Identities = 70/239 (29%), Positives = 106/239 (44%), Gaps = 13/239 (5%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL- 932
++ ++ H + + +G+G+F KV L + TG VAVK +
Sbjct 37 RQNLPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKL----ARHVLTGREVAVKIID 92
Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992
K P +E+ I++ L H +I+K E EK+L LVMEY G + DYL
Sbjct 93 KTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIE--TEKTLYLVMEYASGGEVFDYLVA 150
Query 993 H-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
H + + +QI + Y H + +HRDL A N+LLD D +KI DFG + G
Sbjct 151 HGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADFGFSNEFTVG 210
Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
++ + + APE + K+ DVWS GV LY L++ K L
Sbjct 211 NKL----DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL 265
Score = 182 bits (461), Expect = 7e-46, Method: Composition-based stats.
Identities = 58/320 (18%), Positives = 103/320 (32%), Gaps = 45/320 (14%)
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
P ++S+ + R S + Q +G+G V R + G
Sbjct 31 PAKSSSRQNLPRCRNSITSATDEQPHIG-----NYRLQKTIGKGNFAKVKLARHVLTGR- 84
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAF 672
V +K++D + + + +M ++H ++
Sbjct 85 -----------------------EVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 121
Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVH 732
+ V +V EY G + +L G + +Q+ SA+ Y K +VH
Sbjct 122 LFEVIETEKTLYLVMEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYCHQKCIVH 180
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGAN 789
++ N+LL IK++D G + P+ APE G
Sbjct 181 RDLKAENLLLD-------ADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKY 233
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQC 848
+D W G L + G P ++ E R +R+P L +
Sbjct 234 D-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKL 291
Query 849 LTYEPTQRPSFRTILRDLTR 868
L P +R S I++D
Sbjct 292 LVLNPIKRGSLEQIMKDRWM 311
>sp|Q6C4M9|HOG1_YARLI Mitogen-activated protein kinase HOG1 OS=Yarrowia
lipolytica (strain CLIB 122 / E 150) OX=284591 GN=HOG1
PE=3 SV=1
Length=386
Score = 214 bits (546), Expect = 4e-60, Method: Composition-based stats.
Identities = 67/303 (22%), Positives = 108/303 (36%), Gaps = 29/303 (10%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQ 939
+ + +G G FG V + T + VA+K + K P
Sbjct 4 FIRTQIFGTCFEITSRYVDLNPVGMGAFGLVC----SAKDQLTDQNVAIKKIMKPFGTPV 59
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ 999
+E+ +L+ L HE++I E + V E + L L +
Sbjct 60 LSKRTYRELKLLKHLRHENLICLSDIFISPLED-IYFVTELL-GTDLHRLLMTRPLEKQF 117
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
+ F QI G+ Y+H+ +HRDL N+L++ + +KI DFGLA+
Sbjct 118 IQYFLYQILRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQD------TQMT 171
Query 1060 DGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIG 1113
S ++ APE + K+ D+WS G E+L + EL+G
Sbjct 172 GYVSTRYYRAPEIMLTWQKYDVEVDIWSTGCIFAEMLEGKPLFPGKDHVHQFSIITELLG 231
Query 1114 IAQGQM-------TVLRLTELLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFE 1163
+ LR L R ER+P + E LM+ + R T
Sbjct 232 SPPEDVIHTICSENTLRFVRTLPRRERIPLASKFRNADPEAIDLMEKMLVFDPKKRITAA 291
Query 1164 NLI 1166
+
Sbjct 292 EAL 294
Score = 132 bits (332), Expect = 8e-32, Method: Composition-based stats.
Identities = 53/340 (16%), Positives = 103/340 (30%), Gaps = 49/340 (14%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + +D+ + V +K ++ P ++ Y
Sbjct 10 FGTCFEITSRYVDLNPVGMGAF---GLVCSAKDQLTDQNVAIKKIMKPFGTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H +L + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENLICLSDIFISPLEDIYFVTELL-GTDLHRLLMTR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDTQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGEAPLQSRS---------PS 821
+ APE + +D W G E+ F G+ + S P
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSTGCIFAEMLEGKPLFPGKDHVHQFSIITELLGSPPE 235
Query 822 EKEHFYQ------------RQHRLP-----EPSCPQLATLTSQCLTYEPTQRPSFRTILR 864
+ H R+ R+P + P+ L + L ++P +R + L
Sbjct 236 DVIHTICSENTLRFVRTLPRRERIPLASKFRNADPEAIDLMEKMLVFDPKKRITAAEALA 295
Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
H+ +D S K+
Sbjct 296 HPYLAPYHDPSDEPVAEERFDWSFNDADLPVDTWKVMMYS 335
>sp|Q96S53|TESK2_HUMAN Dual specificity testis-specific protein
kinase 2 OS=Homo sapiens OX=9606 GN=TESK2 PE=1 SV=1
Length=571
Score = 220 bits (560), Expect = 4e-60, Method: Composition-based stats.
Identities = 72/306 (24%), Positives = 130/306 (42%), Gaps = 33/306 (11%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
+ + S + + +G G F +V + + +G+++A+K +
Sbjct 39 WPSSYRALISAFSRLTRLDDFTCEKIGSGFFSEV----FKVRHRASGQVMALKM---NTL 91
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIG 996
+R+ +E+ ++ L H +I+++ G C QG+ L + EY+ G+L L + +
Sbjct 92 SSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQ--LHALTEYINSGNLEQLLDSNLHLP 149
Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHE 1053
+ A I G++YLH + HRDL ++N L+ D + DFGLA+ +P+
Sbjct 150 WTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDVSM 209
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH--CDSSQSPPTKFLEL 1111
SP FW APE L++ + +DV+S+G+ L E++ D P T+ L
Sbjct 210 GSEKLAVVGSP-FWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGL 268
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
A M CP + L NC + RP+F + L+
Sbjct 269 DYDAFQHMVG-----------------DCPPDFLQLTFNCCNMDPKLRPSFVEIGKTLEE 311
Query 1172 VHEKYQ 1177
+ + Q
Sbjct 312 ILSRLQ 317
Score = 197 bits (500), Expect = 3e-52, Method: Composition-based stats.
Identities = 66/314 (21%), Positives = 117/314 (37%), Gaps = 40/314 (13%)
Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622
+ + R P + +F R+ + + +G G + V++ R R
Sbjct 32 VSQVGRVWPSSYRALISAFSRLTRLDDFTCEKIGSGFFSEVFKVRHRA------------ 79
Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
GQ + + + L + ++ + LM+++SH ++ GVCV +
Sbjct 80 ----------SGQVMALKMNTLSSNRANM----LKEVQLMNRLSHPNILRFMGVCVHQGQ 125
Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+TEY+ G L+ L H+P ++ +A +A LSYL K + H ++ +N L+
Sbjct 126 LHALTEYINSGNLEQLL-DSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLI 184
Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMD 796
R + ++D G+ V W+APE L + D
Sbjct 185 KR----DENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRD--EPYNEKAD 238
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQ 855
+ +G L EI +A +E + CP LT C +P
Sbjct 239 VFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKL 298
Query 856 RPSFRTILRDLTRL 869
RPSF I + L +
Sbjct 299 RPSFVEIGKTLEEI 312
>sp|P51954|NEK1_MOUSE Serine/threonine-protein kinase Nek1 OS=Mus
musculus OX=10090 GN=Nek1 PE=1 SV=2
Length=1203
Score = 229 bits (584), Expect = 5e-60, Method: Composition-based stats.
Identities = 64/278 (23%), Positives = 121/278 (44%), Gaps = 28/278 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILR 952
+++ +GEG FGK L + G +K + + + R ++E+ +L
Sbjct 1 MEKYVRLQKIGEGSFGKAVLV----KSTEDGRHYVIKEINISRMSDKERQESRREVAVLA 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICE 1009
+ H +I++YK E+ G SL +VM+Y G L + Q+L + QIC
Sbjct 57 NMKHPNIVQYKESFEENG--SLYIVMDYCEGGDLFKRINAQKGALFQEDQILDWFVQICL 114
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ ++H + +HRD+ ++N+ L D V++GDFG+A+ + E R ++ +
Sbjct 115 ALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELART---CIGTPYYLS 171
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE + + SD+W+ G LYEL T + ++ K L L +
Sbjct 172 PEICENKPYNNKSDIWALGCVLYELCTLKHAFEAGNMKNLVL---------------KII 216
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
G P ++ L+ ++ RP+ +++
Sbjct 217 SGSFPPVSPHYSYDLRSLLSQLFKRNPRDRPSVNSILE 254
Score = 160 bits (405), Expect = 2e-38, Method: Composition-based stats.
Identities = 44/283 (16%), Positives = 91/283 (32%), Gaps = 37/283 (13%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ +L +G+G+ LV + G+ + +
Sbjct 1 MEKYVRLQKIGEGSFGK----------------------AVLVKSTEDGRHYVIKEINIS 38
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
++++ + H ++ +V +Y E G L + ++G
Sbjct 39 RMSDKERQESRREVAVLANMKHPNIVQYKESFEENGSLYIVMDYCEGGDLFKRINAQKGA 98
Query 706 V-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + Q+ AL ++ ++ ++H ++ +NI L + G ++L D G+
Sbjct 99 LFQEDQILDWFVQICLALKHVHDRKILHRDIKSQNIFLTKDG-------TVQLGDFGIAR 151
Query 765 GALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS-RS 819
S + +L+PE + D W G L E+C A
Sbjct 152 VLNSTVELARTCIGTPYYLSPEICEN--KPYNNKSDIWALGCVLYELCTLKHAFEAGNMK 209
Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
+ + L +L SQ P RPS +I
Sbjct 210 NLVLKIISGSFPPVSPHYSYDLRSLLSQLFKRNPRDRPSVNSI 252
>sp|Q42371|ERECT_ARATH LRR receptor-like serine/threonine-protein
kinase ERECTA OS=Arabidopsis thaliana OX=3702 GN=ERECTA
PE=1 SV=1
Length=976
Score = 227 bits (579), Expect = 5e-60, Method: Composition-based stats.
Identities = 72/337 (21%), Positives = 130/337 (39%), Gaps = 25/337 (7%)
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
L L + C P P F D +L +N + + L +
Sbjct 595 LMVLIAAC---RPHNPPPFLDGSLDKPVTYSTPKLVILHMNMALHVYEDIMRMTENLSEK 651
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G V + VA+K L + PQ ++ E+++L ++ H +++
Sbjct 652 YIIGHGASSTVYKCVLKNC-----KPVAIKRLYSH-NPQSMKQFETELEMLSSIKHRNLV 705
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH- 1015
+ L +Y+ GSL D L + ++ L A +G+AYLH
Sbjct 706 SLQAYSLSHLGS--LLFYDYLENGSLWDLLHGPTKKKTLDWDTRLKIAYGAAQGLAYLHH 763
Query 1016 --AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ IHRD+ + N+LLD D ++ DFG+AK++ + + + PE
Sbjct 764 DCSPRIIHRDVKSSNILLDKDLEARLTDFGIAKSLCVSKSH--TSTYVMGTIGYIDPEYA 821
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ + SDV+S+G+ L ELLT + L + + + E+ +
Sbjct 822 RTSRLTEKSDVYSYGIVLLELLTRRKAVDD----ESNLHHLIMSKTGNNEVMEMADPDIT 877
Query 1134 LPRPD-KCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
D +V+ L C + + + RPT + +L
Sbjct 878 STCKDLGVVKKVFQLALLCTKRQPNDRPTMHQVTRVL 914
Score = 188 bits (478), Expect = 2e-47, Method: Composition-based stats.
Identities = 60/360 (17%), Positives = 118/360 (33%), Gaps = 68/360 (19%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ +++ +G G + VY+ L+ V +K L
Sbjct 645 TENLSEKYIIGHGASSTVYKCVLKNCKP-------------------------VAIKRLY 679
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ F ++S + H +L + + +++ +Y+E+G L L
Sbjct 680 SHNPQSMKQFETELEMLSSIKHRNLVSLQAYSLSHLGSLLFYDYLENGSLWDLLHGPTKK 739
Query 706 VPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ W ++ +A A L+YL + ++H +V NILL + A +L+D
Sbjct 740 KTLDWDTRLKIAYGAAQGLAYLHHDCSPRIIHRDVKSSNILLDKDLEA-------RLTDF 792
Query 761 GVGLG-----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ + + + I ++ PE + L+ D + +G LLE+ +A
Sbjct 793 GIAKSLCVSKSHTSTYVMGTIGYIDPEYART--SRLTEKSDVYSYGIVLLELLTRRKAVD 850
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLAT-------------LTSQCLTYEPTQRPSFRTI 862
+ + + E + P + + L C +P RP+ +
Sbjct 851 DESNLHHLIMSKTGNNEVMEMADPDITSTCKDLGVVKKVFQLALLCTKRQPNDRPTMHQV 910
Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH-----------FGKV 911
R L T + A V LK + FG+V
Sbjct 911 TRVLGSFMLSEQPPAATDTSATLAGSCYVDEYANLKTPHSVNCSSMSASDAQLFLRFGQV 970
>sp|O14047|PPK11_SCHPO Serine/threonine-protein kinase ppk11 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=ppk11 PE=3 SV=1
Length=312
Score = 212 bits (539), Expect = 5e-60, Method: Composition-based stats.
Identities = 76/290 (26%), Positives = 118/290 (41%), Gaps = 26/290 (9%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951
K + ++ +G+G FG V + + + ++VA+K + D QEI+ L
Sbjct 1 MEKHQYRDLQLIGQGSFGSV----FRAQDVESSKIVALKVVDLDATKDQIETLTQEINFL 56
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEG 1010
L HI KY D L + MEY GS D L + + +Q+ E
Sbjct 57 IDLNSVHITKYYASFVDGF--RLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEA 114
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
+ YLH Q +HRD+ A N+L D LVK+ DFG++ + + +D FW AP
Sbjct 115 LVYLHGQGKMHRDIKAANILTMKDGLVKLADFGVSGQLESLRDKN---DDFVGTPFWMAP 171
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E +K+ + Y +D+WS G+T YEL T + S L+ I + L ++
Sbjct 172 EVVKQTGYNYKADIWSLGITAYELATG-EPPYSGIHPMKVLLLIPKHSPPSLERSKF--- 227
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180
+ NC + R T E L +KY
Sbjct 228 ----------SRAFCDFVSNCLKKNPKDRATAEYLSKH--KFIKKYCPNT 265
Score = 172 bits (436), Expect = 3e-46, Method: Composition-based stats.
Identities = 63/347 (18%), Positives = 107/347 (31%), Gaps = 52/347 (15%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+++ + L +GQG+ +V+ + D V LKV
Sbjct 1 MEKHQYRDLQLIGQGSFGSVFRAQ------------------------DVESSKIVALKV 36
Query 644 LD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+D + D + + + ++ H+ + V G + EY + G L+
Sbjct 37 VDLDATKDQIETLTQEINFLIDLNSVHITKYYASFVDGFRLWITMEYCDGGSCLDLLKLS 96
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
G V +Q+ AL YL + +H ++ NIL + GL +KL+D GV
Sbjct 97 -GTFSERVIAEVMRQVLEALVYLHGQGKMHRDIKAANILTMKDGL-------VKLADFGV 148
Query 763 GLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
S ++ V W+APE + + D W G T E+ GE P
Sbjct 149 SGQLESLRDKNDDFVGTPFWMAPEVVKQTGYNY--KADIWSLGITAYELA-TGEPPYSGI 205
Query 819 SPSEKEHFYQRQHRLP---EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
P + + S CL P R + + + +
Sbjct 206 HPMKVLLLIPKHSPPSLERSKFSRAFCDFVSNCLKKNPKDRATAEYLSKHKFIKKYCPNT 265
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH---------FGKVSL 913
V V + +G FG V
Sbjct 266 SVKEVVASYAKWKESELLPEATPYNSTMGNSANTIDEVVWDFGTVRR 312
>sp|Q17833|OLD1_CAEEL Tyrosine-protein kinase receptor old-1 OS=Caenorhabditis
elegans OX=6239 GN=old-1 PE=2 SV=3
Length=502
Score = 218 bits (555), Expect = 5e-60, Method: Composition-based stats.
Identities = 90/314 (29%), Positives = 132/314 (42%), Gaps = 30/314 (10%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-----VAVKALKA 934
+ A + K R LG G FG + N E VAVK
Sbjct 158 MYLHYYAEVEINEEDLDISKGRPLGSGEFGIIRKGFLRSKNSKNEEKESRLEVAVKLPLN 217
Query 935 DCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993
+ + E+ ++ + H +I+ G K +V E+V G L +L +
Sbjct 218 EYNQIQQELIYDELKVMCAVGKHPNILALVGGITFGERK--MIVSEFVENGDLLSFLRDN 275
Query 994 ----------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037
S+ L LL FA QI +GM YL +HRDLA RNVL+ +R++
Sbjct 276 RIYFTNDQWTLETEQDSLSLVDLLSFAFQIAKGMEYLIHVPCVHRDLALRNVLIKKNRII 335
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
+I DFGLA+ Y D P+ W APE + + F SDVWS+GV LYEL +
Sbjct 336 RIADFGLARRHKNKDYYKTQSVDTPLPIHWMAPESIDKLLFTQKSDVWSYGVCLYELFSL 395
Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157
S + +I Q + L G+RL +P E+Y++MK CW+ + +
Sbjct 396 GKSP------YENVIKYDQRDFYWKYVLSYLNEGKRLAQPAHADAEIYNVMKLCWDLDMN 449
Query 1158 FRPTFENLIPILKT 1171
R TF + I +
Sbjct 450 SRTTFLDCIEFFEK 463
Score = 189 bits (480), Expect = 4e-50, Method: Composition-based stats.
Identities = 60/312 (19%), Positives = 121/312 (39%), Gaps = 57/312 (18%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-LDP 646
+I++ LG G + +G LR + S ++ L V +K+ L+
Sbjct 174 DISKGRPLGSGEFGIIRKGFLRSKNS---------------KNEEKESRLEVAVKLPLNE 218
Query 647 SHHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-- 703
+ Y+ +M V H ++ + G G ++V+E+VE+G L +LR R
Sbjct 219 YNQIQQELIYDELKVMCAVGKHPNILALVGGITFGERKMIVSEFVENGDLLSFLRDNRIY 278
Query 704 ------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
+ + + A Q+A + YL + VH ++ RN+L+ +
Sbjct 279 FTNDQWTLETEQDSLSLVDLLSFAFQIAKGMEYLIHVPCVHRDLALRNVLIKK------- 331
Query 752 SPFIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+ I+++D G+ +++ I W+APE + + D W +G L
Sbjct 332 NRIIRIADFGLARRHKNKDYYKTQSVDTPLPIHWMAPESIDKLL--FTQKSDVWSYGVCL 389
Query 805 LEICFDGEAPLQSRSPSEKEHFYQR--------QHRL--PEPSCPQLATLTSQCLTYEPT 854
E+ G++P ++ ++ FY + RL P + ++ + C +
Sbjct 390 YELFSLGKSPYENVIKYDQRDFYWKYVLSYLNEGKRLAQPAHADAEIYNVMKLCWDLDMN 449
Query 855 QRPSFRTILRDL 866
R +F +
Sbjct 450 SRTTFLDCIEFF 461
>sp|Q4W6D3|HOG1_COCHE Mitogen-activated protein kinase HOG1 OS=Cochliobolus
heterostrophus OX=5016 GN=HOG1 PE=1 SV=1
Length=355
Score = 213 bits (543), Expect = 5e-60, Method: Composition-based stats.
Identities = 67/276 (24%), Positives = 108/276 (39%), Gaps = 29/276 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VAVK + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SAKDQLTNQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVQ 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFR 1159
L + ER P + + L++N + R
Sbjct 252 SLPKRERQPLANKFKNAEPDAVDLLENMLVFDPRKR 287
Score = 134 bits (338), Expect = 7e-33, Method: Composition-based stats.
Identities = 34/213 (16%), Positives = 69/213 (32%), Gaps = 18/213 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + +D+ V +K ++ P ++ Y
Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSAKDQLTNQAVAVKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ APE + +D W G E+
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML 208
>sp|Q01887|RYK_MOUSE Tyrosine-protein kinase RYK OS=Mus musculus
OX=10090 GN=Ryk PE=1 SV=2
Length=594
Score = 220 bits (561), Expect = 5e-60, Method: Composition-based stats.
Identities = 86/282 (30%), Positives = 135/282 (48%), Gaps = 28/282 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEM--VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
L EG FG++ D E VK +K + E LR L+H +++
Sbjct 323 LQEGTFGRIFHGILVDEKDPNKEKQTF-VKTVKDQASEVQVTMMLTESCKLRGLHHRNLL 381
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQLLLFAQQICEGM 1011
C ++GEK + +V+ Y+ G+L+ +L + +I L+ A QI GM
Sbjct 382 PITHVCIEEGEKPM-VVLPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGM 440
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
+YL + IHRDLAARN ++D+ VKI D L++ + +Y+ + ++ + PV W A E
Sbjct 441 SYLARREVIHRDLAARNCVIDDTLQVKITDNALSRDLFP-MDYHCLGDNENRPVRWMALE 499
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
L +F ASDVW+FGVTL+EL+T L + + L+ G
Sbjct 500 SLVNNEFSSASDVWAFGVTLWELMT--------------LGQTPYVDIDPFEMAAYLKDG 545
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
R+ +P CP E++ +M CW + RP F+ L+ L H
Sbjct 546 YRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFH 587
Score = 192 bits (489), Expect = 1e-50, Method: Composition-based stats.
Identities = 65/334 (19%), Positives = 135/334 (40%), Gaps = 49/334 (15%)
Query 558 TSNLIIMRGARASPRTLNL----SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
+S +R + R++ L +++ + ++ IT L +GT ++ G L
Sbjct 282 SSGYPTLRIEKNDLRSVTLLEAKAKVKDIAISRERITLKDVLQEGTFGRIFHGIL----- 336
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF-YETASLMSQVSHTHLAF 672
V +D +E + +K + ++ + + + + H +L
Sbjct 337 --------------VDEKDPNKEKQTFVKTVKDQASEVQVTMMLTESCKLRGLHHRNLLP 382
Query 673 VHGVCVR-GPENIMVTEYVEHGPLDVWLR-------RERGHVPMAWKMVVAQQLASALSY 724
+ VC+ G + ++V Y+ G L ++LR + + +A Q+A +SY
Sbjct 383 ITHVCIEEGEKPMVVLPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSY 442
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV------ERIPW 778
L + ++H ++ RN ++ + +K++D + + + W
Sbjct 443 LARREVIHRDLAARNCVID-------DTLQVKITDNALSRDLFPMDYHCLGDNENRPVRW 495
Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEP 836
+A E L N S+A D W FG TL E+ G+ P P E + + +R+ P
Sbjct 496 MALESLVN--NEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPIN 553
Query 837 SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+L + + C +P +RP F+ +++ LT
Sbjct 554 CPDELFAVMACCWALDPEERPKFQQLVQCLTEFH 587
>sp|A0A075F7E9|LERK1_ORYSI G-type lectin S-receptor-like serine/threonine-protein
kinase LECRK1 OS=Oryza sativa subsp. indica
OX=39946 GN=LECRK1 PE=1 SV=2
Length=813
Score = 225 bits (573), Expect = 5e-60, Method: Composition-based stats.
Identities = 67/274 (24%), Positives = 113/274 (41%), Gaps = 14/274 (5%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G G V + D +AVK + P+ + E++ + +H+++++
Sbjct 529 LGAGASGVVYKGQLE---DELKTNIAVKTIHK-LQPETEKEFMVEVETIGQTFHKNLVRL 584
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH---AQH 1018
G C ++ E+ LV E++ G L L +S + A + G YLH ++
Sbjct 585 LGFCNERAER--LLVYEFMTNGPLNRLLFDNSRPHWNTRVHIALGVARGFLYLHDECSKQ 642
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IH D+ +N+LLD++ + KI DFGLAK + R + + APE K
Sbjct 643 IIHCDIKPQNILLDDNLVAKISDFGLAKLLLTNQT--RTKTGIRGTRGYVAPEWFKNIGI 700
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI--GIAQGQMTVLRLTELLERGERLPR 1136
DV+SFGV L EL+ + + + I A R+ L+E +
Sbjct 701 STKVDVYSFGVILLELVCCRRNVELEVVDEEQTIVTYWANDCYRSGRIDLLVEGDDEAIY 760
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
K + C + + S RP + +L
Sbjct 761 DIKKVERFVTVALWCLQEDPSMRPNMLKVTQMLD 794
Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats.
Identities = 62/334 (19%), Positives = 118/334 (35%), Gaps = 61/334 (18%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
N+ + + + S L L ++ +++ LG G VY+G+L E +
Sbjct 494 KKNIPLSQASSKSQ--LPLKTFTYKELEKATAGFHEILGAGASGVVYKGQLEDELKTN-- 549
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
+ +K + + F + Q H +L + G C
Sbjct 550 ---------------------IAVKTIHKLQPETEKEFMVEVETIGQTFHKNLVRLLGFC 588
Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGN 734
E ++V E++ +GPL+ L ++ +A +A YL +K ++H +
Sbjct 589 NERAERLLVYEFMTNGPLNRLLFDN-SRPHWNTRVHIALGVARGFLYLHDECSKQIIHCD 647
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGAN 789
+ +NILL + K+SD G+ L+ + R ++APE
Sbjct 648 IKPQNILLD-------DNLVAKISDFGLAKLLLTNQTRTKTGIRGTRGYVAPEWFKNIG- 699
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK------EHFYQRQHRL---------- 833
+ST +D + FG LLE+ E+ + R R+
Sbjct 700 -ISTKVDVYSFGVILLELVCCRRNVELEVVDEEQTIVTYWANDCYRSGRIDLLVEGDDEA 758
Query 834 --PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ T+ CL +P+ RP+ + +
Sbjct 759 IYDIKKVERFVTVALWCLQEDPSMRPNMLKVTQM 792
>sp|M1T7M3|HOG1B_WALI9 Mitogen-activated protein kinase HOG1B
OS=Wallemia ichthyophaga (strain EXF-994 / CBS 113033) OX=1299270
GN=HOG1B PE=1 SV=1
Length=368
Score = 214 bits (544), Expect = 5e-60, Method: Composition-based stats.
Identities = 66/281 (23%), Positives = 108/281 (38%), Gaps = 29/281 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V + T VA+K + K P +E+ +L+ + HE+II
Sbjct 26 VGMGAFGLVC----SAKDQLTSSPVAIKKIMKPFSTPVLSKRTYRELKLLKHIRHENIIS 81
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
E + V E + L L + + F QI G+ Y+H+ +H
Sbjct 82 LSDIFISPSED-IYFVTELL-GTDLHRLLTARPLEKQFIQYFLYQILRGLKYVHSAGVVH 139
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKFYY 1080
RDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 140 RDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKYDV 193
Query 1081 ASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTELL 1128
A D+WS G E+L + + EL+G + LR + L
Sbjct 194 AVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVQSL 253
Query 1129 ERGERLPRPDKC---PCEVYHLMKNCWETEASFRPTFENLI 1166
+ R+P +K L++ + R T +
Sbjct 254 PKKPRIPFNEKFKTNDPLALDLVEKMLSFDPRTRITASQAL 294
Score = 131 bits (330), Expect = 1e-31, Method: Composition-based stats.
Identities = 36/231 (16%), Positives = 76/231 (33%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+++ R G + +D+ V +K ++ P ++ Y
Sbjct 10 FGTLFQITSRYVNLEPVGMGAF---GLVCSAKDQLTSSPVAIKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRGPE-NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + E VTE + L L + +
Sbjct 67 ELKLLKHIRHENIISLSDIFISPSEDIYFVTELL-GTDLHRLLTAR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + A+D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVAVDIWSTGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q9LQQ9|MPK13_ARATH Mitogen-activated protein kinase 13 OS=Arabidopsis
thaliana OX=3702 GN=MPK13 PE=1 SV=1
Length=363
Score = 213 bits (543), Expect = 5e-60, Method: Composition-based stats.
Identities = 75/332 (23%), Positives = 132/332 (40%), Gaps = 35/332 (11%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCG 937
+ + +Y+ I +G G +G V TN T E VA+K + A
Sbjct 15 RYVMYNVLGNIFELSSKYIPPIEPIGRGAYGIVCC----ATNSETNEEVAIKKIANAFDN 70
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL---QLVMEYVPLGSLRDYLPR-H 993
+EI +L + H+++IK K E ++ +V E + L +
Sbjct 71 RVDAKRTLREIKLLSHMDHDNVIKIKDIIELPEKERFEDVYIVYELMD-TDLHQIIRSTQ 129
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
++ F QI G+ Y+H+ + +HRDL N++L+ + +KI DFGLA+ E
Sbjct 130 TLTDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLVLNTNCDLKICDFGLARTSNETE- 188
Query 1054 YYRVREDGDSPVFWYAPE-CLKEYKFYYASDVWSFGVTLYELLTHCDSSQ---------- 1102
+ + ++ APE L ++ A D+WS G E+L
Sbjct 189 ---IMTEYVVTRWYRAPELLLNSSEYTGAIDIWSVGCIFMEILRRETLFPGKDYVQQLKL 245
Query 1103 ------SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156
SP L+ + + V +L + ++ R P+ P + L + +
Sbjct 246 ITELLGSPDDSDLDFLRSDNARKYVKQLPHVQKQSFREKFPNISPMAL-DLAEKMLVFDP 304
Query 1157 SFRPTFENLI--PILKTVHEKYQGQA-PSVFS 1185
S R T + + P L ++HE + P+ FS
Sbjct 305 SKRITVDEALKQPYLASLHEINEEPTCPTPFS 336
Score = 129 bits (323), Expect = 8e-31, Method: Composition-based stats.
Identities = 39/236 (17%), Positives = 81/236 (34%), Gaps = 44/236 (19%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
+ K I + +G+G V + V +K
Sbjct 27 ELSSKYIPPIEPIGRGAYGIVC------------------------CATNSETNEEVAIK 62
Query 643 VLDPSHHDIALAF--YETASLMSQVSHTHLAFVHGVCVRGPE-----NIMVTEYVEHGPL 695
+ + + A L+S + H ++ + + + +V E ++ L
Sbjct 63 KIANAFDNRVDAKRTLREIKLLSHMDHDNVIKIKDIIELPEKERFEDVYIVYELMD-TDL 121
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + Q+ L Y+ + N++H ++ N++L T+ +
Sbjct 122 HQIIRSTQ-TLTDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLVLN-------TNCDL 173
Query 756 KLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
K+ D G+ + E E V + APE L ++ + A+D W G +EI
Sbjct 174 KICDFGLARTSNETEIMTEYVVTRWYRAPELLLN-SSEYTGAIDIWSVGCIFMEIL 228
>sp|Q9LS95|PERK6_ARATH Putative proline-rich receptor-like protein
kinase PERK6 OS=Arabidopsis thaliana OX=3702 GN=PERK6 PE=2
SV=2
Length=700
Score = 223 bits (568), Expect = 5e-60, Method: Composition-based stats.
Identities = 76/278 (27%), Positives = 115/278 (41%), Gaps = 20/278 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G FG V G+ +AVK+LKA G R ++ E+DI+ ++H ++
Sbjct 343 LGQGGFGYVHKGIL-----PNGKEIAVKSLKAGSGQGERE-FQAEVDIISRVHHRFLVSL 396
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLH---A 1016
G C G++ LV E++P +L +L S + L A +G+AYLH
Sbjct 397 VGYCIAGGQR--MLVYEFLPNDTLEFHLHGKSGKVLDWPTRLKIALGSAKGLAYLHEDCH 454
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
IHRD+ A N+LLD K+ DFGLAK + + R + APE
Sbjct 455 PRIIHRDIKASNILLDESFEAKVADFGLAKLSQDNVTHVSTR--IMGTFGYLAPEYASSG 512
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL----RLTELLERGE 1132
K SDV+SFGV L EL+T L+ A+ +EL++
Sbjct 513 KLTDRSDVFSFGVMLLELVTGRRPVDLTGEMEDSLVDWARPICLNAAQDGDYSELVDPRL 572
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
++ A RP ++ L+
Sbjct 573 ENQYEPHEMAQMVACAAAAVRHSARRRPKMSQIVRALE 610
Score = 217 bits (553), Expect = 4e-58, Method: Composition-based stats.
Identities = 55/269 (20%), Positives = 96/269 (36%), Gaps = 46/269 (17%)
Query 574 LNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
N S ++ + + +Q LGQG V++G L
Sbjct 320 FNKSTFTYDELAAATQGFSQSRLLGQGGFGYVHKGILPNGK------------------- 360
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+ +K L F ++S+V H L + G C+ G + ++V E++
Sbjct 361 ------EIAVKSLKAGSGQGEREFQAEVDIISRVHHRFLVSLVGYCIAGGQRMLVYEFLP 414
Query 692 HGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGL 747
+ L+ L + G + ++ +A A L+YL ++H ++ NILL
Sbjct 415 NDTLEFHLHGKSGKVLDWPTRLKIALGSAKGLAYLHEDCHPRIIHRDIKASNILLDE--- 471
Query 748 AEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGA 802
S K++D G+ + V +LAPE G L+ D + FG
Sbjct 472 ----SFEAKVADFGLAKLSQDNVTHVSTRIMGTFGYLAPEYASSG--KLTDRSDVFSFGV 525
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQH 831
LLE+ G P+ E +
Sbjct 526 MLLELV-TGRRPVDLTGEMEDSLVDWARP 553
>sp|Q9LRT1|Y3804_ARATH Probably inactive leucine-rich repeat receptor-like
protein kinase At3g28040 OS=Arabidopsis thaliana
OX=3702 GN=At3g28040 PE=1 SV=1
Length=1016
Score = 228 bits (580), Expect = 5e-60, Method: Composition-based stats.
Identities = 68/281 (24%), Positives = 109/281 (39%), Gaps = 15/281 (5%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG FG V Y G +AVK L Q+ + +E+ IL H +++
Sbjct 731 RIGEGVFGTV----YKAPLGEQGRNLAVKKLVPSPILQNLEDFDREVRILAKAKHPNLVS 786
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHA 1016
KG LV EY+P G+L+ L + +G+AYLH
Sbjct 787 IKGYFWTPDLH--LLVSEYIPNGNLQSKLHEREPSTPPLSWDVRYKIILGTAKGLAYLHH 844
Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC- 1072
IH +L N+LLD KI DFGL++ + + + + APE
Sbjct 845 TFRPTTIHFNLKPTNILLDEKNNPKISDFGLSRLLTTQDGNTMNNNRFQNALGYVAPELE 904
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + DV+ FGV + EL+T + F+ L + + + E ++
Sbjct 905 CQNLRVNEKCDVYGFGVLILELVTGRRPVEYGEDSFVILSDHVRVMLEQGNVLECIDPVM 964
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ V L C S RPT ++ IL+ ++
Sbjct 965 EEQYSEDEVLPVLKLALVCTSQIPSNRPTMAEIVQILQVIN 1005
Score = 176 bits (447), Expect = 1e-43, Method: Composition-based stats.
Identities = 62/332 (19%), Positives = 114/332 (34%), Gaps = 62/332 (19%)
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
F R + + + S +G+G VY+ L +G
Sbjct 717 EFERNPESLLNKASRIGEGVFGTVYKAPLGEQGRNL------------------------ 752
Query 640 VLKVLDPSH-HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+K L PS F ++++ H +L + G +++V+EY+ +G L
Sbjct 753 AVKKLVPSPILQNLEDFDREVRILAKAKHPNLVSIKGYFWTPDLHLLVSEYIPNGNLQSK 812
Query 699 LR-RERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTS 752
L RE P++W + + A L+YL + +H N+ NILL
Sbjct 813 LHEREPSTPPLSWDVRYKIILGTAKGLAYLHHTFRPTTIHFNLKPTNILLDEKNNP---- 868
Query 753 PFIKLSDPGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLL 805
K+SD G+ +++ + ++APE L ++ D +GFG +L
Sbjct 869 ---KISDFGLSRLLTTQDGNTMNNNRFQNALGYVAPE-LECQNLRVNEKCDVYGFGVLIL 924
Query 806 EICFDGEAPLQSRSP----SEKEHFYQRQHRLPEPSCPQLAT------------LTSQCL 849
E+ S+ Q + E P + L C
Sbjct 925 ELVTGRRPVEYGEDSFVILSDHVRVMLEQGNVLECIDPVMEEQYSEDEVLPVLKLALVCT 984
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
+ P+ RP+ I++ L + ++
Sbjct 985 SQIPSNRPTMAEIVQILQVINSPVPHRIMDSF 1016
>sp|Q9SR87|LRK61_ARATH Probable L-type lectin-domain containing
receptor kinase VI.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK61
PE=2 SV=1
Length=693
Score = 223 bits (567), Expect = 5e-60, Method: Composition-based stats.
Identities = 69/299 (23%), Positives = 121/299 (40%), Gaps = 22/299 (7%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH 940
P + K+ +G G FG V N + +AVK + ++ Q
Sbjct 352 YPHRFRYRDLYLATKKFKESEIIGTGGFGIVYRG-----NLSSSGPIAVKKITSN-SLQG 405
Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------ 994
+ EI+ L L H++++ +G C+ + E L L+ +Y+P GSL L +
Sbjct 406 VREFMAEIESLGRLGHKNLVNLQGWCKHKNE--LLLIYDYIPNGSLDSLLYQTPRRNGIV 463
Query 995 IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051
+ + I G+ YLH + +HRD+ NVL+D D K+GDFGLA+ G
Sbjct 464 LPWDVRFEIIKGIASGLLYLHEEWEQIVVHRDVKPSNVLIDEDMNAKLGDFGLARLYERG 523
Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111
+ + + APE + K ASDV++FGV L E++ + + + L
Sbjct 524 TLTQTTK--IVGTLGYMAPELTRNGKGSTASDVFAFGVLLLEIVCGNKPTNA---ENFFL 578
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
T + ++++ + + C + FRP+ ++ L
Sbjct 579 ADWVMEFHTNGGILCVVDQNLGSSFNGREAKLALVVGLLCCHQKPKFRPSMRMVLRYLN 637
Score = 210 bits (535), Expect = 8e-56, Method: Composition-based stats.
Identities = 64/314 (20%), Positives = 108/314 (34%), Gaps = 73/314 (23%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ K+ + +G G VY G L G + +K
Sbjct 363 LATKKFKESEIIGTGGFGIVYRGNLSSSGP-------------------------IAVKK 397
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---- 699
+ + F + ++ H +L + G C E +++ +Y+ +G LD L
Sbjct 398 ITSNSLQGVREFMAEIESLGRLGHKNLVNLQGWCKHKNELLLIYDYIPNGSLDSLLYQTP 457
Query 700 RRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIK 756
RR +P + + + +AS L YL + +VH +V N+L+ K
Sbjct 458 RRNGIVLPWDVRFEIIKGIASGLLYLHEEWEQIVVHRDVKPSNVLIDE-------DMNAK 510
Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
L D G+ + V + ++APE G STA D + FG LLEI
Sbjct 511 LGDFGLARLYERGTLTQTTKIVGTLGYMAPELTRNGKG--STASDVFAFGVLLLEIV--- 565
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ--------------------CLTY 851
P+ E+F+ + + + + Q C
Sbjct 566 ----CGNKPTNAENFFLADWVMEFHTNGGILCVVDQNLGSSFNGREAKLALVVGLLCCHQ 621
Query 852 EPTQRPSFRTILRD 865
+P RPS R +LR
Sbjct 622 KPKFRPSMRMVLRY 635
>sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo
sapiens OX=9606 GN=NUAK1 PE=1 SV=1
Length=661
Score = 222 bits (565), Expect = 5e-60, Method: Composition-based stats.
Identities = 68/292 (23%), Positives = 114/292 (39%), Gaps = 31/292 (11%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC- 936
K + LG+G +GKV T +G +VA+K+++ D
Sbjct 36 PRKPHGVKRHHHKHNLKHRYELQETLGKGTYGKVK----RATERFSGRVVAIKSIRKDKI 91
Query 937 -GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHS 994
Q ++EI+I+ +L H HII E++ + + ++MEY G L DY+ R
Sbjct 92 KDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDK--IVIIMEYASKGELYDYISERRR 149
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ + F +QI + Y H +HRDL N+LLD++ +KI DFGL+ +
Sbjct 150 LSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKD--- 206
Query 1055 YRVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
+ + + +PE + + D W+ GV LY L+
Sbjct 207 -KFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFD----------- 254
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L + GE R P + L++ R T E++
Sbjct 255 ----GFDHKNLIRQISSGEY--REPTQPSDARGLIRWMLMVNPDRRATIEDI 300
Score = 169 bits (428), Expect = 2e-42, Method: Composition-based stats.
Identities = 57/357 (16%), Positives = 101/357 (28%), Gaps = 41/357 (11%)
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGS 613
PG + A PR + + H+ + K LG+GT V R G
Sbjct 20 PGSPREAVAGATAALEPRKPHGVKRHHHKHNLKHRYELQETLGKGTYGKVKRATERFSGR 79
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETASLMSQVSHTHL 670
V +K + + +MS ++H H+
Sbjct 80 ------------------------VVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHI 115
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730
++ V + +++ EY G L ++ ER + +Q+ SA+ Y +
Sbjct 116 ISIYEVFENKDKIVIIMEYASKGELYDYI-SERRRLSERETRHFFRQIVSAVHYCHKNGV 174
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGG 787
VH ++ NILL + IK++D G+ + + +PE + G
Sbjct 175 VHRDLKLENILLD-------DNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGR 227
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ 847
+D W G L + G P L
Sbjct 228 PYR-GPEVDSWALGVLLYTLV-YGTMPFDGFDHKNLIRQISSGEYREPTQPSDARGLIRW 285
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
L P +R + I + + S + + L
Sbjct 286 MLMVNPDRRATIEDIANHWWVNWGYKSSVCDCDALHDSESPLLARIIDWHHRSTGLQ 342
>sp|Q2WGK3|HOG1_TRIHA Mitogen-activated protein kinase hog1 OS=Trichoderma
harzianum OX=5544 GN=hog1 PE=1 SV=1
Length=356
Score = 213 bits (542), Expect = 6e-60, Method: Composition-based stats.
Identities = 68/293 (23%), Positives = 112/293 (38%), Gaps = 31/293 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VAVK + K P +E+ +L+ L HE++
Sbjct 24 QPVGMGAFGLVC----SARDQLTNQNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENV 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHE 1174
L + ER P + L++ + R T + L+ H+
Sbjct 252 SLPKRERQPLRNKFKNADDSAIDLLERMLVFDPKKRVTATQALAHEYLQPYHD 304
Score = 130 bits (326), Expect = 3e-31, Method: Composition-based stats.
Identities = 37/231 (16%), Positives = 75/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E D + M + RD+ V +K ++ P +A Y
Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAVKKIMKPFSTPVLAKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q2ULU3|STE20_ASPOR Serine/threonine-protein kinase ste20 OS=Aspergillus
oryzae (strain ATCC 42149 / RIB 40) OX=510516
GN=ste20 PE=3 SV=1
Length=848
Score = 225 bits (574), Expect = 6e-60, Method: Composition-based stats.
Identities = 60/275 (22%), Positives = 119/275 (43%), Gaps = 23/275 (8%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
+ + +G+G G V + ++GTG VA+K + D P+ + EI +++
Sbjct 563 PTKMYYNLNKIGQGASGGV----FTAYHNGTGSCVAIKQMNLDLQPK-KDLIINEIIVMK 617
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
H++I+ + + L +VMEY+ GSL D + + + Q+ ++ G+
Sbjct 618 DSKHKNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMSEGQIAAVCRETLNGLQ 675
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+LH++ IHRD+ + N+LL D +K+ DFG + ++ + R +W APE
Sbjct 676 HLHSKGVIHRDIKSDNILLSLDGNIKLTDFGFCAQI---NDSHNKRNTMVGTPYWMAPEV 732
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ ++ D+WS G+ E++ + + L IA ++ + L
Sbjct 733 VTRKEYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLIATNGTPTIKDEQSLTPVF 791
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
R + HL + + R + +L+
Sbjct 792 R---------DFLHLA---LKVDPEKRASAHDLLK 814
Score = 176 bits (446), Expect = 7e-44, Method: Composition-based stats.
Identities = 53/293 (18%), Positives = 93/293 (32%), Gaps = 44/293 (15%)
Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651
L+ +GQG V+ G V +K ++
Sbjct 570 LNKIGQGASGGVF------------------------TAYHNGTGSCVAIKQMNLDLQPK 605
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711
+M H ++ + G + +V EY+E G L + +
Sbjct 606 KDLIINEIIVMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVV--TFNIMSEGQI 663
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--- 768
V ++ + L +L +K ++H ++ NILL+ IKL+D G
Sbjct 664 AAVCRETLNGLQHLHSKGVIHRDIKSDNILLS-------LDGNIKLTDFGFCAQINDSHN 716
Query 769 -REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
R V W+APE + +D W G +E+ +GE P + SP +
Sbjct 717 KRNTMVGTPYWMAPEVVT--RKEYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLI 773
Query 828 QRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
+ P L +P +R S +L+ L+
Sbjct 774 ATNGTPTIKDEQSLTPVFRDFLHLALKVDPEKRASAHDLLKHPFMSFCAPLSH 826
>sp|P42818|KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6
OS=Arabidopsis thaliana OX=3702 GN=ATPK1 PE=1 SV=1
Length=465
Score = 216 bits (551), Expect = 6e-60, Method: Composition-based stats.
Identities = 67/260 (26%), Positives = 110/260 (42%), Gaps = 30/260 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960
+G+G FGKV Y T E+ A+K ++ D H K E DIL + H I+
Sbjct 140 VGKGAFGKV----YQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPFIV 195
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHY 1019
+ K Q + L LV++++ G L L + ++ +I +++LH +
Sbjct 196 QLKYSF--QTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGI 253
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDL N+L+D D V + DFGLAK E + + APE ++
Sbjct 254 MHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSM----CGTTEYMAPEIVRGKGHD 309
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
A+D WS G+ LYE+LT K + ++++ +L P
Sbjct 310 KAADWWSVGILLYEMLTGKPPFLGSKGKIQQ---------------KIVKDKIKL--PQF 352
Query 1140 CPCEVYHLMKNCWETEASFR 1159
E + ++K + E R
Sbjct 353 LSNEAHAILKGLLQKEPERR 372
Score = 156 bits (395), Expect = 2e-39, Method: Composition-based stats.
Identities = 48/324 (15%), Positives = 102/324 (31%), Gaps = 35/324 (11%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V + + +G+G VY+ R + + D +
Sbjct 129 VGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDH------------------I 170
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
++ +H + A +++++ H + + +V +++ G L L +
Sbjct 171 MEKNHAEYMKA---ERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQ- 226
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
G V ++ SA+S+L K ++H ++ NIL+ G + L+D G+
Sbjct 227 GLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDTDG-------HVMLTDFGLA 279
Query 764 LGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
++APE + G A D W G L E+ G+ P
Sbjct 280 KEFEENTRSNSMCGTTEYMAPEIVRG--KGHDKAADWWSVGILLYEML-TGKPPFLGSKG 336
Query 821 SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880
++ + + +LP+ + + L EP +R + +
Sbjct 337 KIQQKIVKDKIKLPQFLSNEAHAILKGLLQKEPERRLGSGLSGAEEIKQHKWFKGINWKK 396
Query 881 NPDSPASDPTVFHKRYLKKIRDLG 904
+ I +
Sbjct 397 LEAREVMPSFKPEVSGRQCIANFD 420
>sp|A9TF79|SRK2A_PHYPA Serine/threonine-protein kinase SRK2A OS=Physcomitrium
patens OX=3218 GN=SRK2A PE=1 SV=1
Length=349
Score = 213 bits (541), Expect = 6e-60, Method: Composition-based stats.
Identities = 72/281 (26%), Positives = 117/281 (42%), Gaps = 30/281 (11%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+ + ++D+G G+FG L + T E+VAVK + + G + ++EI
Sbjct 6 MHDHDRYELVKDIGSGNFGVARLM----RDKKTRELVAVKYI--ERGEKIDENVQREIIN 59
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICE 1009
R+L H +I+++K L +VMEY G L + + + F QQ+
Sbjct 60 HRSLRHPNIVRFKEVMLTPTH--LAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLIS 117
Query 1010 GMAYLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
G++Y H+ HRDL N LLD +KI DFG +K + + +
Sbjct 118 GVSYCHSMQICHRDLKLENTLLDGSPAPRLKICDFGYSK----SSLLHSQPKSTVGTPAY 173
Query 1068 YAPECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSP--PTKFLELIGIAQGQMTVLRL 1124
APE L + ++ +DVWS GVTLY +L + P P F + IG
Sbjct 174 IAPEVLSKKEYDGKIADVWSCGVTLYVMLVGAYPFEDPEDPRNFRKTIG----------- 222
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+L +P E HL+ + + R + +
Sbjct 223 -RILSVQYSIPDYVHISVECRHLLSRIFVANPAKRINIQEI 262
Score = 157 bits (397), Expect = 1e-40, Method: Composition-based stats.
Identities = 57/332 (17%), Positives = 100/332 (30%), Gaps = 47/332 (14%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
D + +G G RD+ V +K +
Sbjct 8 DHDRYELVKDIGSGNFG------------------------VARLMRDKKTRELVAVKYI 43
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ I + H ++ V + +V EY G L + G
Sbjct 44 ERG-EKIDENVQREIINHRSLRHPNIVRFKEVMLTPTHLAIVMEYAAGGELFERI-CNAG 101
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
QQL S +SY + + H ++ N LL +P +K+ D G
Sbjct 102 RFSEDEARFFFQQLISGVSYCHSMQICHRDLKLENTLLD-----GSPAPRLKICDFGYSK 156
Query 765 GAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+L + V ++APE L D W G TL + G P + P
Sbjct 157 SSLLHSQPKSTVGTPAYIAPEVLSKKEYD-GKIADVWSCGVTLYVMLV-GAYPFED--PE 212
Query 822 EKEHFYQRQHRL--PEPSCPQLATLTSQCLT-------YEPTQRPSFRTILRDLTRLQPH 872
+ +F + R+ + S P ++ +C P +R + + I L+
Sbjct 213 DPRNFRKTIGRILSVQYSIPDYVHISVECRHLLSRIFVANPAKRINIQEIKNHEWFLKNL 272
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
V + DP + + +R +
Sbjct 273 PADLVDLADRSYDFEDPNHPPQSIEEIMRIIS 304
>sp|P0C5D6|SAPK3_ORYSJ Serine/threonine-protein kinase SAPK3 OS=Oryza
sativa subsp. japonica OX=39947 GN=SAPK3 PE=1 SV=1
Length=334
Score = 212 bits (540), Expect = 6e-60, Method: Composition-based stats.
Identities = 77/283 (27%), Positives = 118/283 (42%), Gaps = 33/283 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+LG G+FG L + + E+VAVK + + G + ++EI R+L H +II+
Sbjct 10 ELGAGNFGVARLV----RDKRSKELVAVKYI--ERGKKIDENVQREIINHRSLRHPNIIR 63
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+K C L +VMEY G L + + + F QQ+ G++Y H+
Sbjct 64 FKEVCLTPTH--LAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSLEIC 121
Query 1021 HRDLAARNVLLDNDRL--VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N LLD VKI DFG +K + + + +P + APE L ++
Sbjct 122 HRDLKLENTLLDGSPTPRVKICDFGYSK---SALLHSKPKSTVGTPA-YIAPEVLSRKEY 177
Query 1079 YYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
DVWS GVTLY +L + P G R T G + P
Sbjct 178 DGKVADVWSCGVTLYVMLVGSYPFEDP------------GDPRNFRKTISRILGVQYSIP 225
Query 1138 DK--CPCEVYHLMKNCWETEASFRPTFENLIP---ILKTVHEK 1175
D + L+ + + S R T + LK + ++
Sbjct 226 DYVRVSSDCRRLLSQIFVADPSKRITIPEIKKHTWFLKNLPKE 268
Score = 159 bits (401), Expect = 2e-41, Method: Composition-based stats.
Identities = 55/295 (19%), Positives = 89/295 (30%), Gaps = 41/295 (14%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ L LG G RD+ + V +K ++
Sbjct 2 EERYEALKELGAGNFG------------------------VARLVRDKRSKELVAVKYIE 37
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
I + H ++ VC+ +V EY G L + G
Sbjct 38 RGKK-IDENVQREIINHRSLRHPNIIRFKEVCLTPTHLAIVMEYAAGGELFEQI-CTAGR 95
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
QQL S +SY + + H ++ N LL +P +K+ D G
Sbjct 96 FSEDEARYFFQQLISGVSYCHSLEICHRDLKLENTLLD-----GSPTPRVKICDFGYSKS 150
Query 766 AL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
AL + V ++APE L D W G TL + P
Sbjct 151 ALLHSKPKSTVGTPAYIAPEVLSRKEYD-GKVADVWSCGVTLYVMLVGSYPFEDPGDPRN 209
Query 823 KEHFYQR----QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
R Q+ +P+ L SQ +P++R + I + L+
Sbjct 210 FRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFVADPSKRITIPEIKKHTWFLKN 264
>sp|A2ZAB5|SAPK3_ORYSI Serine/threonine-protein kinase SAPK3 OS=Oryza
sativa subsp. indica OX=39946 GN=SAPK3 PE=1 SV=2
Length=334
Score = 212 bits (540), Expect = 6e-60, Method: Composition-based stats.
Identities = 77/283 (27%), Positives = 118/283 (42%), Gaps = 33/283 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+LG G+FG L + + E+VAVK + + G + ++EI R+L H +II+
Sbjct 10 ELGAGNFGVARLV----RDKRSKELVAVKYI--ERGKKIDENVQREIINHRSLRHPNIIR 63
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+K C L +VMEY G L + + + F QQ+ G++Y H+
Sbjct 64 FKEVCLTPTH--LAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSLEIC 121
Query 1021 HRDLAARNVLLDNDRL--VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N LLD VKI DFG +K + + + +P + APE L ++
Sbjct 122 HRDLKLENTLLDGSPTPRVKICDFGYSK---SALLHSKPKSTVGTPA-YIAPEVLSRKEY 177
Query 1079 YYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
DVWS GVTLY +L + P G R T G + P
Sbjct 178 DGKVADVWSCGVTLYVMLVGSYPFEDP------------GDPRNFRKTISRILGVQYSIP 225
Query 1138 DK--CPCEVYHLMKNCWETEASFRPTFENLIP---ILKTVHEK 1175
D + L+ + + S R T + LK + ++
Sbjct 226 DYVRVSSDCRRLLSQIFVADPSKRITIPEIKKHTWFLKNLPKE 268
Score = 159 bits (401), Expect = 2e-41, Method: Composition-based stats.
Identities = 55/295 (19%), Positives = 89/295 (30%), Gaps = 41/295 (14%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ L LG G RD+ + V +K ++
Sbjct 2 EERYEALKELGAGNFG------------------------VARLVRDKRSKELVAVKYIE 37
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
I + H ++ VC+ +V EY G L + G
Sbjct 38 RGKK-IDENVQREIINHRSLRHPNIIRFKEVCLTPTHLAIVMEYAAGGELFEQI-CTAGR 95
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
QQL S +SY + + H ++ N LL +P +K+ D G
Sbjct 96 FSEDEARYFFQQLISGVSYCHSLEICHRDLKLENTLLD-----GSPTPRVKICDFGYSKS 150
Query 766 AL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
AL + V ++APE L D W G TL + P
Sbjct 151 ALLHSKPKSTVGTPAYIAPEVLSRKEYD-GKVADVWSCGVTLYVMLVGSYPFEDPGDPRN 209
Query 823 KEHFYQR----QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
R Q+ +P+ L SQ +P++R + I + L+
Sbjct 210 FRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFVADPSKRITIPEIKKHTWFLKN 264
>sp|Q6H7D2|SIT1_ORYSJ L-type lectin-domain containing receptor
kinase SIT1 OS=Oryza sativa subsp. japonica OX=39947 GN=SIT1
PE=1 SV=1
Length=674
Score = 222 bits (566), Expect = 6e-60, Method: Composition-based stats.
Identities = 71/275 (26%), Positives = 116/275 (42%), Gaps = 16/275 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG+V Y + +AVK + + Q + E+ + L H ++++
Sbjct 363 LGFGGFGRV----YKGVLLVSRVEIAVKKVSHE-SRQGMKEFIAEVVSIGQLRHRNLVQL 417
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018
G C +GE L LV +Y+P GSL YL + AQ + I + YLH
Sbjct 418 LGYCRQKGE--LLLVYDYMPNGSLDKYLYAENSKILSWAQRFRIIKGIASSILYLHEDWE 475
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRD+ A NVLLD + ++GDFGLA+ G + + + + APE
Sbjct 476 QVVLHRDIKASNVLLDAEMNCRLGDFGLARLYDRGTDPHTTH--VVGTIGYLAPELGHTG 533
Query 1077 KFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ ASD+++FGV + E+ Q L L+ + +T+ ++ +
Sbjct 534 RPSKASDIFAFGVFMLEVTCGRRPVLQDTNGGQLLLVDMVLEHWRQGTVTDAVDPRLQGD 593
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ V L C S RP ++ +L
Sbjct 594 FAVEEASLVLKLCLLCSHPLPSARPGIRQVVQLLD 628
Score = 212 bits (539), Expect = 2e-56, Method: Composition-based stats.
Identities = 64/339 (19%), Positives = 114/339 (34%), Gaps = 61/339 (18%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ LG G VY+G L V + + +K +
Sbjct 353 ATNGFSDERLLGFGGFGRVYKGVLLV------------------------SRVEIAVKKV 388
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
F + Q+ H +L + G C + E ++V +Y+ +G LD +L E
Sbjct 389 SHESRQGMKEFIAEVVSIGQLRHRNLVQLLGYCRQKGELLLVYDYMPNGSLDKYLYAENS 448
Query 705 H-VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ A + + + +AS++ YL + ++H ++ N+LL +L D
Sbjct 449 KILSWAQRFRIIKGIASSILYLHEDWEQVVLHRDIKASNVLLD-------AEMNCRLGDF 501
Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ V I +LAPE G S A D + FG +LE+ G P+
Sbjct 502 GLARLYDRGTDPHTTHVVGTIGYLAPEL--GHTGRPSKASDIFAFGVFMLEV-TCGRRPV 558
Query 816 QSRSPSEKEHF------YQRQHRLPEPSCPQL------------ATLTSQCLTYEPTQRP 857
+ + + RQ + + P+L L C P+ RP
Sbjct 559 LQDTNGGQLLLVDMVLEHWRQGTVTDAVDPRLQGDFAVEEASLVLKLCLLCSHPLPSARP 618
Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896
R +++ L P ++ + A
Sbjct 619 GIRQVVQLLDGAMPLPELSQAHLSCNMLALMQNQMGNSC 657
>sp|Q75DK7|STE20_EREGS Serine/threonine-protein kinase STE20 OS=Eremothecium
gossypii (strain ATCC 10895 / CBS 109.51 / FGSC
9923 / NRRL Y-1056) OX=284811 GN=STE20 PE=3 SV=2
Length=970
Score = 227 bits (578), Expect = 6e-60, Method: Composition-based stats.
Identities = 65/282 (23%), Positives = 118/282 (42%), Gaps = 25/282 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G G V Y GT VA+K + + P+ + EI +++ H +I+
Sbjct 688 KIGQGASGGV----YTAYEIGTNASVAIKQMNLEKQPK-KELIINEILVMKGSRHNNIVN 742
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
+ +G+ L ++MEY+ GSL D + + Q+ +++ G+ +LH++ IH
Sbjct 743 FIDSYLLKGD--LWVIMEYMEGGSLTDVVTHCILTEGQIAAVSRETLRGLHFLHSKGVIH 800
Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081
RD+ + N+LL D +K+ DFG + +E R +W APE + ++
Sbjct 801 RDIKSDNILLSMDGNIKLTDFGFCAQI---NETNLKRTTMVGTPYWMAPEVVSRKEYGPK 857
Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141
D+WS G+ + E++ + T L IA L+ + L
Sbjct 858 VDIWSLGIMIIEMI-EGEPPYLNETPLRALYLIATNGTPKLKDADSL------------S 904
Query 1142 CEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAP 1181
+ + C + + R T L+ + V E AP
Sbjct 905 PVLKRFLSWCLQVSPNDRATAMELLYDKFIVEVAEANASLAP 946
Score = 185 bits (469), Expect = 2e-46, Method: Composition-based stats.
Identities = 51/277 (18%), Positives = 90/277 (32%), Gaps = 44/277 (16%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
+GQG VY + G V +K ++
Sbjct 688 KIGQGASGGVY------------------------TAYEIGTNASVAIKQMNLEKQPKKE 723
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
+M H ++ + + ++ EY+E G L + +
Sbjct 724 LIINEILVMKGSRHNNIVNFIDSYLLKGDLWVIMEYMEGGSLTDVVTH--CILTEGQIAA 781
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSR 769
V+++ L +L +K ++H ++ NILL+ IKL+D G L R
Sbjct 782 VSRETLRGLHFLHSKGVIHRDIKSDNILLS-------MDGNIKLTDFGFCAQINETNLKR 834
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
V W+APE + +D W G ++E+ +GE P + +P +
Sbjct 835 TTMVGTPYWMAPEVVS--RKEYGPKVDIWSLGIMIIEMI-EGEPPYLNETPLRALYLIAT 891
Query 830 QHRLP----EPSCPQLATLTSQCLTYEPTQRPSFRTI 862
+ P L S CL P R + +
Sbjct 892 NGTPKLKDADSLSPVLKRFLSWCLQVSPNDRATAMEL 928
>sp|Q52PH6|HOG1_ALTBR Mitogen-activated protein kinase HOG1 OS=Alternaria
brassicicola OX=29001 GN=HOG1 PE=3 SV=1
Length=355
Score = 213 bits (542), Expect = 6e-60, Method: Composition-based stats.
Identities = 66/276 (24%), Positives = 107/276 (39%), Gaps = 29/276 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VA+K + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SAKDQLTSQAVAIKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVQ 251
Query 1127 LLERGERLPRP---DKCPCEVYHLMKNCWETEASFR 1159
L + ER P + L++N + R
Sbjct 252 SLPKRERQPLSNKFKNAEPQAVDLLENMLVFDPKKR 287
Score = 134 bits (337), Expect = 1e-32, Method: Composition-based stats.
Identities = 35/231 (15%), Positives = 74/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + +D+ V +K ++ P ++ Y
Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSAKDQLTSQAVAIKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q9LPZ9|SD113_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase SD1-13 OS=Arabidopsis thaliana OX=3702
GN=SD113 PE=1 SV=2
Length=830
Score = 225 bits (573), Expect = 6e-60, Method: Composition-based stats.
Identities = 74/279 (27%), Positives = 110/279 (39%), Gaps = 17/279 (6%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG+G FG V G +AVK L G + + I L H +++
Sbjct 516 NKLGQGGFGAVYKGRLQE-----GLDIAVKRLSRTSGQGVEEFVNEVVVI-SKLQHRNLV 569
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016
+ G C + E+ LV E++P L YL + + IC G+ YLH
Sbjct 570 RLLGFCIEGEER--MLVYEFMPENCLDAYLFDPVKQRLLDWKTRFNIIDGICRGLMYLHR 627
Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRDL A N+LLD + KI DFGLA+ +G+E + APE
Sbjct 628 DSRLKIIHRDLKASNILLDENLNPKISDFGLARIF-QGNEDEVSTVRVVGTYGYMAPEYA 686
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
F SDV+S GV L E+++ SS + L A L++
Sbjct 687 MGGLFSEKSDVFSLGVILLEIVSGRRNSSFYNDGQNPNLSAYAWKLWNTGEDIALVDPVI 746
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+ H+ C + A+ RP+ +I +L +
Sbjct 747 FEECFENEIRRCVHVGLLCVQDHANDRPSVATVIWMLSS 785
Score = 216 bits (551), Expect = 4e-57, Method: Composition-based stats.
Identities = 57/274 (21%), Positives = 97/274 (35%), Gaps = 46/274 (17%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
+ L L + V + + LGQG VY+GRL+
Sbjct 495 KELPLFEFQVLAVATNNFSITNKLGQGGFGAVYKGRLQEG-------------------- 534
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
L + +K L + F ++S++ H +L + G C+ G E ++V E++
Sbjct 535 -----LDIAVKRLSRTSGQGVEEFVNEVVVISKLQHRNLVRLLGFCIEGEERMLVYEFMP 589
Query 692 HGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLG 746
LD +L + W + + + L YL ++H ++ NILL
Sbjct 590 ENCLDAYLFDPVKQRLLDWKTRFNIIDGICRGLMYLHRDSRLKIIHRDLKASNILLDE-- 647
Query 747 LAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800
+ K+SD G+ +S V ++APE GG S D +
Sbjct 648 -----NLNPKISDFGLARIFQGNEDEVSTVRVVGTYGYMAPEYAMGGL--FSEKSDVFSL 700
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834
G LLEI G + + + +L
Sbjct 701 GVILLEIVS-GRRNSSFYNDGQNPNLSAYAWKLW 733
>sp|Q9S9M1|WAKLE_ARATH Wall-associated receptor kinase-like 5
OS=Arabidopsis thaliana OX=3702 GN=WAKL5 PE=2 SV=2
Length=731
Score = 223 bits (569), Expect = 6e-60, Method: Composition-based stats.
Identities = 69/279 (25%), Positives = 111/279 (40%), Gaps = 18/279 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G G V G+++AVK K + EI +L + H +I+K
Sbjct 438 LGKGSQGTVYKGM-----MVDGKIIAVKRSKV-VDEDKLEKFINEIILLSQINHRNIVKL 491
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQ- 1017
GCC + E + LV EY+P G + L S + L A +I + Y+H+
Sbjct 492 IGCCLE-TEVPI-LVYEYIPNGDMFKRLHDESDDYAMTWEVRLRIAIEIAGALTYMHSAA 549
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
HRD+ N+LLD K+ DFG +++V + G + PE
Sbjct 550 SFPIYHRDIKTTNILLDEKYGAKVSDFGTSRSVTIDQTHLTTMVAG--TFGYMDPEYFLS 607
Query 1076 YKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
++ SDV+SFGV L EL+T S+ + L M R+ ++++ +
Sbjct 608 SQYTDKSDVYSFGVVLVELITGEKPLSRIRSEEGRGLATHFLEAMKENRVIDIIDIRIKE 667
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
V L + C + RP L+ +
Sbjct 668 ESKLDQLMAVAKLARKCLSRKGIKRPNMREASLELERIR 706
Score = 211 bits (537), Expect = 8e-56, Method: Composition-based stats.
Identities = 58/305 (19%), Positives = 105/305 (34%), Gaps = 63/305 (21%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ LG+G++ VY+G + + +K
Sbjct 428 ATDNFSVKRVLGKGSQGTVYKGMMVDGKI-------------------------IAVKRS 462
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D F L+SQ++H ++ + G C+ I+V EY+ +G + L E
Sbjct 463 KVVDEDKLEKFINEIILLSQINHRNIVKLIGCCLETEVPILVYEYIPNGDMFKRLHDESD 522
Query 705 HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
M W ++ +A ++A AL+Y+ + + H ++ NILL A K+SD
Sbjct 523 DYAMTWEVRLRIAIEIAGALTYMHSAASFPIYHRDIKTTNILLDEKYGA-------KVSD 575
Query 760 PGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G + ++ PE ++ + D + FG L+E+ GE P
Sbjct 576 FGTSRSVTIDQTHLTTMVAGTFGYMDPEYFL--SSQYTDKSDVYSFGVVLVELI-TGEKP 632
Query 815 LQSRSPSEKEHFYQRQHRLPE------------------PSCPQLATLTSQCLTYEPTQR 856
L E + +A L +CL+ + +R
Sbjct 633 LSRIRSEEGRGLATHFLEAMKENRVIDIIDIRIKEESKLDQLMAVAKLARKCLSRKGIKR 692
Query 857 PSFRT 861
P+ R
Sbjct 693 PNMRE 697
>sp|Q0U4L8|HOG1_PHANO Mitogen-activated protein kinase HOG1 OS=Phaeosphaeria
nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)
OX=321614 GN=HOG1 PE=3 SV=2
Length=355
Score = 213 bits (542), Expect = 6e-60, Method: Composition-based stats.
Identities = 67/276 (24%), Positives = 107/276 (39%), Gaps = 29/276 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VA+K + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SAKDQLTSQAVAIKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
DVWS G E+L + + EL+G + LR +
Sbjct 192 DVEVDVWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIHTICSENTLRFVQ 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFR 1159
L + ER P + L++N + R
Sbjct 252 SLPKRERQPLANKFKNAEPAAVDLLENMLVFDPKKR 287
Score = 135 bits (339), Expect = 5e-33, Method: Composition-based stats.
Identities = 34/213 (16%), Positives = 69/213 (32%), Gaps = 18/213 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + +D+ V +K ++ P ++ Y
Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSAKDQLTSQAVAIKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ APE + +D W G E+
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDVWSAGCIFAEML 208
>sp|P34925|RYK_HUMAN Tyrosine-protein kinase RYK OS=Homo sapiens
OX=9606 GN=RYK PE=1 SV=3
Length=607
Score = 220 bits (561), Expect = 7e-60, Method: Composition-based stats.
Identities = 85/281 (30%), Positives = 136/281 (48%), Gaps = 26/281 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVA-VKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
L EG FG++ D E A VK +K + E LR L+H +++
Sbjct 336 LQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLP 395
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQLLLFAQQICEGMA 1012
C ++GEK + +++ Y+ G+L+ +L + +I L+ A QI GM+
Sbjct 396 ITHVCIEEGEKPM-VILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMS 454
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
YL + IH+DLAARN ++D+ VKI D L++ + +Y+ + ++ + PV W A E
Sbjct 455 YLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFP-MDYHCLGDNENRPVRWMALES 513
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
L +F ASDVW+FGVTL+EL+T L + + L+ G
Sbjct 514 LVNNEFSSASDVWAFGVTLWELMT--------------LGQTPYVDIDPFEMAAYLKDGY 559
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
R+ +P CP E++ +M CW + RP F+ L+ L H
Sbjct 560 RIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFH 600
Score = 189 bits (480), Expect = 2e-49, Method: Composition-based stats.
Identities = 65/345 (19%), Positives = 136/345 (39%), Gaps = 49/345 (14%)
Query 547 LRRCCLPQPGETSNLIIMRGARASPRTLNL----SQLSFHRVDQKEITQLSHLGQGTRTN 602
LR ++ +R + R++ L ++ + ++ IT L +GT
Sbjct 284 LRADTPNNATPITSYPTLRIEKNDLRSVTLLEAKGKVKDIAISRERITLKDVLQEGTFGR 343
Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF-YETASL 661
++ G L + +D +E + +K + +I + +
Sbjct 344 IFHGIL-------------------IDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCK 384
Query 662 MSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDVWLR-------RERGHVPMAWKMV 713
+ + H +L + VC+ G + +++ Y+ G L ++LR + +
Sbjct 385 LRGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVH 444
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773
+A Q+A +SYL + ++H ++ RN ++ + +K++D + +
Sbjct 445 MAIQIACGMSYLARREVIHKDLAARNCVID-------DTLQVKITDNALSRDLFPMDYHC 497
Query 774 ------ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
+ W+A E L N S+A D W FG TL E+ G+ P P E +
Sbjct 498 LGDNENRPVRWMALESLVN--NEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYL 555
Query 828 QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ +R+ P +L + + C +P +RP F+ +++ LT
Sbjct 556 KDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFH 600
>sp|Q32L23|LIMK2_BOVIN LIM domain kinase 2 OS=Bos taurus OX=9913
GN=LIMK2 PE=2 SV=1
Length=638
Score = 221 bits (563), Expect = 7e-60, Method: Composition-based stats.
Identities = 77/302 (25%), Positives = 130/302 (43%), Gaps = 38/302 (13%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948
+F L LG+G FG+ T+ TG+++ + L C + + + E+
Sbjct 323 QQIFRPCDLIHGEVLGKGFFGQ----AIKVTHKATGKVMVMNEL-IRCDEETQKTFLTEV 377
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQI 1007
++R+L H +++K+ G +K L L+ EY+ G+L+D+L Q + FA+ I
Sbjct 378 KVMRSLDHPNVLKFIGVLYK--DKKLNLLTEYIEGGTLKDFLRNVDPFPWQQKVRFAKGI 435
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY------------- 1054
GMAYLH+ IHRDL + N L+ D+ V + DFGL++ + E +
Sbjct 436 ASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKKPPVEKATTKKRTL 495
Query 1055 ----YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
+ R +W APE L + DV+SFG+ L E++ + + L+
Sbjct 496 RKSDRKKRYTVVGNPYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLD 555
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
G L + + P++CP + L C E RP F L +
Sbjct 556 F-----GLNVKLFWEKFV--------PEECPPAFFPLAAICCRLEPESRPAFSKLEDFFE 602
Query 1171 TV 1172
+
Sbjct 603 AL 604
Score = 200 bits (509), Expect = 8e-53, Method: Composition-based stats.
Identities = 62/345 (18%), Positives = 114/345 (33%), Gaps = 62/345 (18%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK-EITQLSHLGQGTRTNVYEGRLRVE 611
P P +++ + +L S ++ + ++ LG+G + +
Sbjct 294 PGPSSPKEPLLLSRDISRSESLRCSSSCSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKAT 353
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
G +V+ L + F +M + H ++
Sbjct 354 GK------------------------VMVMNELIRCDEETQKTFLTEVKVMRSLDHPNVL 389
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
GV + + ++TEY+E G L +LR P K+ A+ +AS ++YL + ++
Sbjct 390 KFIGVLYKDKKLNLLTEYIEGGTLKDFLRNVD-PFPWQQKVRFAKGIASGMAYLHSMCII 448
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------------------------GAL 767
H ++ N L+ + ++D G+
Sbjct 449 HRDLNSHNCLI-------KLDKTVVVADFGLSRLIVEERKKPPVEKATTKKRTLRKSDRK 501
Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--FDGEAPLQSRSPSEKEH 825
R V W+APE L G S +D + FG L EI + R+ +
Sbjct 502 KRYTVVGNPYWMAPEMLNG--KSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLN 559
Query 826 FY-QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ +PE P L + C EP RP+F + L
Sbjct 560 VKLFWEKFVPEECPPAFFPLAAICCRLEPESRPAFSKLEDFFEAL 604
>sp|Q09170|CDS1_SCHPO Serine/threonine-protein kinase cds1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=cds1 PE=1 SV=2
Length=460
Score = 216 bits (551), Expect = 7e-60, Method: Composition-based stats.
Identities = 77/309 (25%), Positives = 122/309 (39%), Gaps = 40/309 (13%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
V + + + + IR LG G F V L +G+ A+K +
Sbjct 145 CQVPVKHSRDSQKNMIKSENSHYEIIRTLGSGTFAVVKL----AVEVNSGKWYAIKIINK 200
Query 935 ------DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
+ +++EIDIL++L+H +++ E+ E L +VMEYV G L D
Sbjct 201 RKILLTSSEKRATEMFQREIDILKSLHHPGVVQCHEIFENDDE--LFIVMEYVEGGDLMD 258
Query 989 YL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
+L SI +Q+ E + +LH Q HRD+ N+L+ ND +KI DFGLAK
Sbjct 259 FLIANGSIDEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKV 318
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLK------EYKFYYASDVWSFGVTLYELLTHCDSS 1101
+ H E + + APE LK + + D+WS G LY +LT
Sbjct 319 I---HGTGTFLETFCGTMGYLAPEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLT----- 370
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP---DKCPCEVYHLMKNCWETEASF 1158
I + + EL+ +G P ++ E L+ E
Sbjct 371 ----------ASIPFASSSQAKCIELISKGAYPIEPLLENEISEEGIDLINRMLEINPEK 420
Query 1159 RPTFENLIP 1167
R + +
Sbjct 421 RISESEALQ 429
Score = 155 bits (391), Expect = 7e-39, Method: Composition-based stats.
Identities = 54/327 (17%), Positives = 95/327 (29%), Gaps = 49/327 (15%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
SQ + + + + LG GT V G + + L R E
Sbjct 155 SQKNMIKSENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATE 214
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+ F ++ + H + H + E +V EYVE G L
Sbjct 215 M-----------------FQREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLM 257
Query 697 VWL-----RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
+L E+ P+ +++ +L + + H ++ NIL+
Sbjct 258 DFLIANGSIDEQDCKPLLKQLLETL------LHLHKQGVTHRDIKPENILITN------- 304
Query 752 SPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGG----ANSLSTAMDKWGFGAT 803
+K+SD G+ E + +LAPE L +D W G
Sbjct 305 DFHLKISDFGLAKVIHGTGTFLETFCGTMGYLAPEVLKSKNVNLDGGYDDKVDIWSLGCV 364
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQ-----HRLPEPSCPQLATLTSQCLTYEPTQRPS 858
L + P S S ++ + L + L ++ L P +R S
Sbjct 365 LY-VMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISEEGIDLINRMLEINPEKRIS 423
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSP 885
L+ +
Sbjct 424 ESEALQHPWFYTVSTHEHRTPPSSSEH 450
>sp|Q9FJI4|LK111_ARATH Putative L-type lectin-domain containing
receptor kinase I.11 OS=Arabidopsis thaliana OX=3702 GN=LECRK111
PE=3 SV=1
Length=675
Score = 222 bits (565), Expect = 7e-60, Method: Composition-based stats.
Identities = 76/300 (25%), Positives = 124/300 (41%), Gaps = 20/300 (7%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
+P + K LG+G FG+V D +AVK + D Q
Sbjct 331 YSPHRFSYKSLYKATNRFDKDGRLGKGGFGEVYRGNLPHVGD-----IAVKRVCHDA-KQ 384
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIG 996
+ E+ + +L H +++ G C +GE L LV EY+ GSL YL + ++
Sbjct 385 GMKQFVAEVVTMGSLKHRNLVPLLGYCRRKGE--LLLVSEYMSNGSLDQYLFHREKPALS 442
Query 997 LAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+Q L+ + I ++YLH Q +HRD+ A NV+LD++ ++GDFG+A+ G
Sbjct 443 WSQRLVILKDIASALSYLHTGANQVVLHRDIKASNVMLDSEFNGRLGDFGMARFEDYGDS 502
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLEL 1111
+ + APE L +DV++FGV + E +T P P++ L
Sbjct 503 VPVT--AAVGTMGYMAPE-LTTMGTSTRTDVYAFGVLMLE-VTCGRRPLDPKIPSEKRHL 558
Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
I + + ++ + V L C A RPT E +I +
Sbjct 559 IKWVCDCWRRDSIVDAIDTRLGGQYSVEETVMVLKLGLICTNIVAESRPTMEQVIQYINQ 618
Score = 219 bits (557), Expect = 8e-59, Method: Composition-based stats.
Identities = 62/277 (22%), Positives = 104/277 (38%), Gaps = 60/277 (22%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ LG+G VY G L G + +K +
Sbjct 344 ATNRFDKDGRLGKGGFGEVYRGNLPHVGD-------------------------IAVKRV 378
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL-RRER 703
F M + H +L + G C R E ++V+EY+ +G LD +L RE+
Sbjct 379 CHDAKQGMKQFVAEVVTMGSLKHRNLVPLLGYCRRKGELLLVSEYMSNGSLDQYLFHREK 438
Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ + ++V+ + +ASALSYL N+ ++H ++ N++L +L D
Sbjct 439 PALSWSQRLVILKDIASALSYLHTGANQVVLHRDIKASNVMLDSEFNG-------RLGDF 491
Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ ++ V + ++APE G ST D + FG +LE+ G PL
Sbjct 492 GMARFEDYGDSVPVTAAVGTMGYMAPELTTMGT---STRTDVYAFGVLMLEV-TCGRRPL 547
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYE 852
+ PSEK H + C +
Sbjct 548 DPKIPSEKRHLIKW---------------VCDCWRRD 569
>sp|Q9P0L2|MARK1_HUMAN Serine/threonine-protein kinase MARK1 OS=Homo
sapiens OX=9606 GN=MARK1 PE=1 SV=2
Length=795
Score = 224 bits (572), Expect = 7e-60, Method: Composition-based stats.
Identities = 70/249 (28%), Positives = 110/249 (44%), Gaps = 13/249 (5%)
Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923
+ + + ++ ++ H + + +G+G+F KV L + T
Sbjct 27 PHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKL----ARHVLT 82
Query 924 GEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982
G VAVK + K P +E+ I++ L H +I+K E EK+L LVMEY
Sbjct 83 GREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIE--TEKTLYLVMEYAS 140
Query 983 LGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
G + DYL H + + +QI + Y H ++ +HRDL A N+LLD D +KI D
Sbjct 141 GGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIAD 200
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDS 1100
FG + G++ + + APE + K+ DVWS GV LY L++
Sbjct 201 FGFSNEFTVGNKL----DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLP 256
Query 1101 SQSPPTKFL 1109
K L
Sbjct 257 FDGQNLKEL 265
Score = 182 bits (463), Expect = 4e-46, Method: Composition-based stats.
Identities = 62/354 (18%), Positives = 111/354 (31%), Gaps = 45/354 (13%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
QP ++S+ + R S + Q +G+G V R + G
Sbjct 30 QPTKSSSRQNIPRCRNSITSATDEQPHIG-----NYRLQKTIGKGNFAKVKLARHVLTGR 84
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLA 671
V +K++D + + + +M ++H ++
Sbjct 85 ------------------------EVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIV 120
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
+ V +V EY G + +L G + +Q+ SA+ Y K +V
Sbjct 121 KLFEVIETEKTLYLVMEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYCHQKYIV 179
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGA 788
H ++ N+LL IK++D G + P+ APE G
Sbjct 180 HRDLKAENLLLD-------GDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKK 232
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQ 847
+D W G L + G P ++ E R +R+P L +
Sbjct 233 YD-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 290
Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901
L P +R S I++D H ++ P + T +
Sbjct 291 LLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGF 344
>sp|O15865|CDPK2_PLAFK Calcium-dependent protein kinase 2 OS=Plasmodium
falciparum (isolate K1 / Thailand) OX=5839 GN=CDPK2
PE=1 SV=3
Length=513
Score = 218 bits (555), Expect = 7e-60, Method: Composition-based stats.
Identities = 68/333 (20%), Positives = 125/333 (38%), Gaps = 36/333 (11%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
+ + T+ + + + LG+G +G V
Sbjct 29 ENTSKQSNDYKYDINTSCISREGTTTLERKNLILCHSGKLEDKYIIDEKLGQGTYGCV-- 86
Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
Y + T ++ A+K K D ++ + + QEI+I++ L H +I+K E +
Sbjct 87 --YKGIDKVTNQLYAIKEEKKD-RLKNINRFFQEIEIMKKLDHPNIVKLYETYE--NDNY 141
Query 974 LQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL- 1031
+ L+ME L D + S +QI + YLH+ + +HRDL N L
Sbjct 142 IYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNIVHRDLKPENFLFQ 201
Query 1032 --DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
+ D L+KI DFGL+K + G ++ AP+ L + K+ D+WS GV
Sbjct 202 SENKDSLLKIIDFGLSKNLGTGE----FTTTKAGTPYYVAPQVL-DGKYDKKCDIWSSGV 256
Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC---PCEVYH 1146
+Y LL T + + +++GE + + +
Sbjct 257 IMYTLLCGYPPFYGD---------------TDNEVLKKVKKGEFCFYENDWGSISSDAKN 301
Query 1147 LMKNCWETEASFRPTFENLI--PILKTVHEKYQ 1177
L+ + R T E + P + + + ++
Sbjct 302 LITKLLTYNPNERCTIEEALNHPWITQMTKSHE 334
Score = 183 bits (464), Expect = 6e-48, Method: Composition-based stats.
Identities = 49/300 (16%), Positives = 94/300 (31%), Gaps = 41/300 (14%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ + LGQGT VY+G D+ +K
Sbjct 69 EDKYIIDEKLGQGTYGCVYKGI------------------------DKVTNQLYAIKEEK 104
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
F++ +M ++ H ++ ++ ++ E L + E G
Sbjct 105 KDRLKNINRFFQEIEIMKKLDHPNIVKLYETYENDNYIYLIMELCSGRELFDSII-ENGS 163
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+ +Q+ SA+ YL + N+VH ++ N L +E +K+ D G+
Sbjct 164 FTEKNAATIMKQIFSAIFYLHSLNIVHRDLKPENFL----FQSENKDSLLKIIDFGLSKN 219
Query 766 ALS---REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ + ++AP+ L G D W G + + G P + +E
Sbjct 220 LGTGEFTTTKAGTPYYVAPQVLDG---KYDKKCDIWSSGVIMYTLLC-GYPPFYGDTDNE 275
Query 823 KEHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
++ L ++ LTY P +R + L Q +
Sbjct 276 VLKKVKKGEFCFYENDWGSISSDAKNLITKLLTYNPNERCTIEEALNHPWITQMTKSHEH 335
>sp|Q8ICR0|CDPK2_PLAF7 Calcium-dependent protein kinase 2 OS=Plasmodium
falciparum (isolate 3D7) OX=36329 GN=CDPK2 PE=1 SV=4
Length=513
Score = 218 bits (555), Expect = 7e-60, Method: Composition-based stats.
Identities = 68/333 (20%), Positives = 125/333 (38%), Gaps = 36/333 (11%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
+ + T+ + + + LG+G +G V
Sbjct 29 ENTSKQSNDYKYDINTSCISREGTTTLERKNLILCHSGKLEDKYIIDEKLGQGTYGCV-- 86
Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973
Y + T ++ A+K K D ++ + + QEI+I++ L H +I+K E +
Sbjct 87 --YKGIDKVTNQLYAIKEEKKD-RLKNINRFFQEIEIMKKLDHPNIVKLYETYE--NDNY 141
Query 974 LQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL- 1031
+ L+ME L D + S +QI + YLH+ + +HRDL N L
Sbjct 142 IYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNIVHRDLKPENFLFQ 201
Query 1032 --DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089
+ D L+KI DFGL+K + G ++ AP+ L + K+ D+WS GV
Sbjct 202 SENKDSLLKIIDFGLSKNLGTGE----FTTTKAGTPYYVAPQVL-DGKYDKKCDIWSSGV 256
Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC---PCEVYH 1146
+Y LL T + + +++GE + + +
Sbjct 257 IMYTLLCGYPPFYGD---------------TDNEVLKKVKKGEFCFYENDWGSISSDAKN 301
Query 1147 LMKNCWETEASFRPTFENLI--PILKTVHEKYQ 1177
L+ + R T E + P + + + ++
Sbjct 302 LITKLLTYNPNERCTIEEALNHPWITQMTKSHE 334
Score = 183 bits (464), Expect = 6e-48, Method: Composition-based stats.
Identities = 49/300 (16%), Positives = 94/300 (31%), Gaps = 41/300 (14%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ + LGQGT VY+G D+ +K
Sbjct 69 EDKYIIDEKLGQGTYGCVYKGI------------------------DKVTNQLYAIKEEK 104
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
F++ +M ++ H ++ ++ ++ E L + E G
Sbjct 105 KDRLKNINRFFQEIEIMKKLDHPNIVKLYETYENDNYIYLIMELCSGRELFDSII-ENGS 163
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+ +Q+ SA+ YL + N+VH ++ N L +E +K+ D G+
Sbjct 164 FTEKNAATIMKQIFSAIFYLHSLNIVHRDLKPENFL----FQSENKDSLLKIIDFGLSKN 219
Query 766 ALS---REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ + ++AP+ L G D W G + + G P + +E
Sbjct 220 LGTGEFTTTKAGTPYYVAPQVLDG---KYDKKCDIWSSGVIMYTLLC-GYPPFYGDTDNE 275
Query 823 KEHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
++ L ++ LTY P +R + L Q +
Sbjct 276 VLKKVKKGEFCFYENDWGSISSDAKNLITKLLTYNPNERCTIEEALNHPWITQMTKSHEH 335
>sp|Q7Y0B9|SAPK8_ORYSJ Serine/threonine-protein kinase SAPK8 OS=Oryza
sativa subsp. japonica OX=39947 GN=SAPK8 PE=1 SV=1
Length=371
Score = 213 bits (543), Expect = 7e-60, Method: Composition-based stats.
Identities = 73/284 (26%), Positives = 122/284 (43%), Gaps = 26/284 (9%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
P + + +RD+G G+FG L + T E+VAVK + + G + +
Sbjct 22 MDMPIMHDSDRYELVRDIGSGNFGVARLM----RDRRTMELVAVKYI--ERGEKIDDNVQ 75
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFA 1004
+EI R+L H +II++K L +VMEY G L + + ++ + F
Sbjct 76 REIINHRSLKHPNIIRFKEVILTPTH--LAIVMEYASGGELFERICKNVRFSEDEARYFF 133
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
QQ+ G++Y H+ HRDL N LLD +KI DFG +K + + +
Sbjct 134 QQLISGVSYCHSMQVCHRDLKLENTLLDGSPAPRLKICDFGYSK---SSVLHSQPKSTVG 190
Query 1063 SPVFWYAPECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
+P + APE L + ++ +DVWS GVTLY ++ + P + +
Sbjct 191 TPA-YIAPEVLLKKEYDGKTADVWSCGVTLYVMVVGAYPFEDPE----------EPKNFR 239
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ +L +P E HL+ + + S R T +
Sbjct 240 KTIQRILNVQYSIPENVDISPECRHLISRIFVGDPSLRITIPEI 283
Score = 154 bits (388), Expect = 3e-39, Method: Composition-based stats.
Identities = 55/329 (17%), Positives = 97/329 (29%), Gaps = 41/329 (12%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
D + +G G RDR V +K +
Sbjct 29 DSDRYELVRDIGSGNFG------------------------VARLMRDRRTMELVAVKYI 64
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ I + H ++ V + +V EY G L + +
Sbjct 65 ERG-EKIDDNVQREIINHRSLKHPNIIRFKEVILTPTHLAIVMEYASGGELFERICKNV- 122
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
QQL S +SY + + H ++ N LL +P +K+ D G
Sbjct 123 RFSEDEARYFFQQLISGVSYCHSMQVCHRDLKLENTLLD-----GSPAPRLKICDFGYSK 177
Query 765 GAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
++ + V ++APE L T D W G TL + P
Sbjct 178 SSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKT-ADVWSCGVTLYVMVVGAYPFEDPEEPK 236
Query 822 E----KEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ Q+ +PE P+ L S+ +P+ R + I L+
Sbjct 237 NFRKTIQRILNVQYSIPENVDISPECRHLISRIFVGDPSLRITIPEIRSHGWFLKNLPAD 296
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
+ + S +P + + ++ L
Sbjct 297 LMDDDSMSSQYEEPDQPMQTMDQIMQILT 325
>sp|Q8T0S6|HIPPO_DROME Serine/threonine-protein kinase hippo OS=Drosophila
melanogaster OX=7227 GN=hpo PE=1 SV=1
Length=669
Score = 222 bits (565), Expect = 7e-60, Method: Composition-based stats.
Identities = 64/279 (23%), Positives = 113/279 (41%), Gaps = 27/279 (10%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
++ + LGEG +G V Y + + +VA+K + + +EI I
Sbjct 36 QPPEKVFDIMYKLGEGSYGSV----YKAVHKESSSIVAIKLVPVESDLH---EIIKEISI 88
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQIC 1008
++ ++++Y G Q + L + MEY GS+ D L + ++ ++
Sbjct 89 MQQCDSPYVVRYYGSYFKQYD--LWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTL 146
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+G+ YLH + IHRD+ A N+LL+ + K+ DFG+A + + R FW
Sbjct 147 QGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMA---KRNTVIGTPFWM 203
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
APE ++E + +D+WS G+T E+ G + + +
Sbjct 204 APEVIEEIGYDCVADIWSLGITALEMAEGKPPY-----------GEIHPMRAIFMIPQKP 252
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
R PD+ E + C E R T L+
Sbjct 253 PPSFR--EPDRWSTEFIDFVSKCLVKEPDDRATATELLE 289
Score = 191 bits (486), Expect = 1e-49, Method: Composition-based stats.
Identities = 71/386 (18%), Positives = 126/386 (33%), Gaps = 61/386 (16%)
Query 553 PQPGETSNLIIMRGARASPRTL-----NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
E ++++ M+ S LS+ S + +K + LG+G+ +VY+
Sbjct 1 MSEPEVTSVVDMKSPNISSSCSFFKLKKLSEESLLQPPEKVFDIMYKLGEGSYGSVYKAV 60
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667
+ S V +K L P D+ + S+M Q
Sbjct 61 HKESSS------------------------IVAIK-LVPVESDLH-EIIKEISIMQQCDS 94
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
++ +G + + + EY G + +R + + + L YL
Sbjct 95 PYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHL 154
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIPWLAPEC 783
+ +H ++ NILL G + KL+D GV R + W+APE
Sbjct 155 RRKIHRDIKAANILLNTEG-------YAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEV 207
Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCP 839
+ D W G T LE+ +G+ P P ++ R P+
Sbjct 208 IEE--IGYDCVADIWSLGITALEMA-EGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWST 264
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899
+ S+CL EP R + +L + + + + ++ A R
Sbjct 265 EFIDFVSKCLVKEPDDRATATELLEHEFIRNAKHRSILKPMLEETCAIREQQRANR---- 320
Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGE 925
FG V L + T E
Sbjct 321 -------SFGGV-LAASQAKSLATQE 338
>sp|Q7XUN6|SIT2_ORYSJ L-type lectin-domain containing receptor
kinase SIT2 OS=Oryza sativa subsp. japonica OX=39947 GN=SIT2
PE=2 SV=2
Length=673
Score = 222 bits (565), Expect = 7e-60, Method: Composition-based stats.
Identities = 75/296 (25%), Positives = 119/296 (40%), Gaps = 16/296 (5%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
P + R LG G FG+V Y + VAVK + A Q
Sbjct 337 PHRFSYKDLFHATDGFSDKRLLGIGGFGRV----YRGVLPSSKAEVAVKKV-AHGSRQGM 391
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLA 998
+ E+ + L H ++++ G C +GE L LV +Y+P GSL L + ++ A
Sbjct 392 REFVAEVVSIGRLRHRNLVQLLGYCRRKGE--LLLVYDYMPNGSLDKQLYDQGKITLRWA 449
Query 999 QLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
Q + + G+ YLH +HRD+ A NVLLD D ++GDFGLA+ G + +
Sbjct 450 QRFRIIRGVASGLLYLHEDWEQVVVHRDIKASNVLLDADMNGRLGDFGLARLYDHGTDPH 509
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGI 1114
+ + APE K ASDV++FG + E+ +Q + L+
Sbjct 510 TTH--VVGTMGYLAPELGHTGKASKASDVFAFGAFMLEVACGRKPVAQDARDNRVVLVDW 567
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ +T+ ++ + V L C RP L+ L+
Sbjct 568 VLDRWRAGAITDTVDPRLHGDFVESEASLVLRLGLLCSHPLPGARPGTRQLVQYLE 623
Score = 206 bits (524), Expect = 2e-54, Method: Composition-based stats.
Identities = 66/352 (19%), Positives = 110/352 (31%), Gaps = 61/352 (17%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ LG G VY G L + V +K +
Sbjct 348 ATDGFSDKRLLGIGGFGRVYRGVL------------------------PSSKAEVAVKKV 383
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-R 703
F + ++ H +L + G C R E ++V +Y+ +G LD L + +
Sbjct 384 AHGSRQGMREFVAEVVSIGRLRHRNLVQLLGYCRRKGELLLVYDYMPNGSLDKQLYDQGK 443
Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ A + + + +AS L YL + +VH ++ N+LL +L D
Sbjct 444 ITLRWAQRFRIIRGVASGLLYLHEDWEQVVVHRDIKASNVLLD-------ADMNGRLGDF 496
Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ V + +LAPE G S A D + FGA +LE+ +
Sbjct 497 GLARLYDHGTDPHTTHVVGTMGYLAPEL--GHTGKASKASDVFAFGAFMLEVACGRKPVA 554
Query 816 QSRSPSEKEHFYQRQHR-----LPEPSCPQLA------------TLTSQCLTYEPTQRPS 858
Q + R + + P+L L C P RP
Sbjct 555 QDARDNRVVLVDWVLDRWRAGAITDTVDPRLHGDFVESEASLVLRLGLLCSHPLPGARPG 614
Query 859 FRTILRDLTRLQPHNL--ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
R +++ L P + N + D + G F
Sbjct 615 TRQLVQYLEGDVPLPELSPTYQSFNMLALMQDQGFDPYVMSYPMTSTSAGTF 666
>sp|P0DP15|SNF1_FUSVI Sucrose non-fermenting protein kinase 1
OS=Fusarium virguliforme OX=232082 GN=SNF1 PE=3 SV=1
Length=698
Score = 222 bits (566), Expect = 8e-60, Method: Composition-based stats.
Identities = 82/268 (31%), Positives = 119/268 (44%), Gaps = 31/268 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEHI 959
LGEG FGKV L ++GTG+ VA+K + K ++EI+ L+ L H HI
Sbjct 67 TLGEGSFGKVKL----AIHNGTGQQVALKIIARKKLISRDMAGRVEREIEYLQLLRHPHI 122
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018
IK + E + +V+EY G L DY+ +H + A+ F QQ+ + Y H
Sbjct 123 IKLYTVIKTPNE--IIMVLEYA-GGELFDYIVQHGRMKEAEARRFFQQMLCAVEYCHRHK 179
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRDL N+LLD + VKI DFGL+ + +G+ ++ SP + APE + +
Sbjct 180 IVHRDLKPENLLLDENLNVKIADFGLSNIMTDGN---FLKTSCGSPN-YAAPEVIGGKLY 235
Query 1079 -YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
DVWS GV LY LL L IA+G + P
Sbjct 236 AGPEVDVWSCGVILYVLLVGRLPFDDEHIPSL-FAKIAKGTYS---------------IP 279
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165
P +L+K R T E++
Sbjct 280 QWMPLGAANLIKKMLVVNPVHRATIEDI 307
Score = 174 bits (442), Expect = 5e-44, Method: Composition-based stats.
Identities = 56/306 (18%), Positives = 98/306 (32%), Gaps = 36/306 (12%)
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
G+R + L + R+ ++ L LG+G+ V G +
Sbjct 41 GSRPADAPLKERIKTEQRIGAYKV--LRTLGEGSFGKVKLAIHNGTGQQVALKI------ 92
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
+ K L + + + H H+ ++ V E IM
Sbjct 93 -------------IARKKLISRDMAGRVE--REIEYLQLLRHPHIIKLYTVIKTPNEIIM 137
Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
V EY G L ++ + G + A QQ+ A+ Y +VH ++ N+LL
Sbjct 138 VLEYA-GGELFDYI-VQHGRMKEAEARRFFQQMLCAVEYCHRHKIVHRDLKPENLLLDE- 194
Query 746 GLAEGTSPFIKLSDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+ +K++D G+ + + APE + GG +D W G
Sbjct 195 ------NLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVI-GGKLYAGPEVDVWSCGV 247
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
L + PS + + +P+ A L + L P R + I
Sbjct 248 ILYVLLVGRLPFDDEHIPSLFAKIAKGTYSIPQWMPLGAANLIKKMLVVNPVHRATIEDI 307
Query 863 LRDLTR 868
D
Sbjct 308 RADPWF 313
>sp|Q9LMN6|WAK4_ARATH Wall-associated receptor kinase 4 OS=Arabidopsis
thaliana OX=3702 GN=WAK4 PE=2 SV=1
Length=738
Score = 223 bits (568), Expect = 8e-60, Method: Composition-based stats.
Identities = 75/344 (22%), Positives = 129/344 (38%), Gaps = 24/344 (7%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTR------LQPHNLADVLTVNPDSPASDPTVFHKRYL 897
L C+ ++ + + +Q + A V+ +
Sbjct 351 LAISCIEHKMKNTKDTELRQQFFEQNGGGMLMQRLSGAGPSNVDVKIFTEEGMKEATDGY 410
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+ R LG+G G V +VA+K + Q + E+ +L + H
Sbjct 411 DENRILGQGGQGTVYKGIL-----PDNSIVAIKKARLGDNSQ-VEQFINEVLVLSQINHR 464
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAY 1013
+++K GCC + E L LV E++ G+L D+L S+ L A +I +AY
Sbjct 465 NVVKLLGCCLE-TEVPL-LVYEFISSGTLFDHLHGSMFDSSLTWEHRLRMAVEIAGTLAY 522
Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
LH+ IHRD+ N+LLD + K+ DFG ++ +P E G + + P
Sbjct 523 LHSSASIPIIHRDIKTANILLDENLTAKVADFGASRLIPMDKEDLATMVQG--TLGYLDP 580
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E SDV+SFGV L ELL+ + P ++ RL E+++
Sbjct 581 EYYNTGLLNEKSDVYSFGVVLMELLSGQKALCFERPQTSKHIVSYFASATKENRLHEIID 640
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ + + C RP + + L+ +
Sbjct 641 GQVMNENNQREIQKAARIAVECTRLTGEERPGMKEVAAELEALR 684
Score = 205 bits (522), Expect = 6e-54, Method: Composition-based stats.
Identities = 62/361 (17%), Positives = 124/361 (34%), Gaps = 63/361 (17%)
Query 559 SNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616
+++ R + A P +++ + + + LGQG + VY+G L
Sbjct 378 GGMLMQRLSGAGPSNVDVKIFTEEGMKEATDGYDENRILGQGGQGTVYKGILPDNSI--- 434
Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676
V +K + F ++SQ++H ++ + G
Sbjct 435 ----------------------VAIKKARLGDNSQVEQFINEVLVLSQINHRNVVKLLGC 472
Query 677 CVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLV 731
C+ ++V E++ G L L + W ++ +A ++A L+YL + ++
Sbjct 473 CLETEVPLLVYEFISSGTLFDHLHGSMFDSSLTWEHRLRMAVEIAGTLAYLHSSASIPII 532
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIPWLAPECLPG 786
H ++ NILL + K++D G +E + +L PE
Sbjct 533 HRDIKTANILLDE-------NLTAKVADFGASRLIPMDKEDLATMVQGTLGYLDPEYYNT 585
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-----RQHRLPEPSCPQL 841
G L+ D + FG L+E+ +A R + K +++RL E Q+
Sbjct 586 GL--LNEKSDVYSFGVVLMELLSGQKALCFERPQTSKHIVSYFASATKENRLHEIIDGQV 643
Query 842 ------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
A + +C +RP + + +L L+ +
Sbjct 644 MNENNQREIQKAARIAVECTRLTGEERPGMKEVAAELEALRVTKTKHKWSDEYPEQEDTE 703
Query 890 T 890
Sbjct 704 H 704
>sp|P27636|CDC15_YEAST Cell division control protein 15 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=CDC15 PE=1 SV=3
Length=974
Score = 227 bits (578), Expect = 8e-60, Method: Composition-based stats.
Identities = 72/274 (26%), Positives = 112/274 (41%), Gaps = 31/274 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
+ +G G +G V Y N T ++VA+K + + + + EI +L+ L
Sbjct 24 QYHLKQVIGRGSYGVV----YKAINKHTDQVVAIKEVVYE-NDEELNDIMAEISLLKNLN 78
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAY 1013
H +I+KY G E L +++EY GSLR + R S + + + Q G+ Y
Sbjct 79 HNNIVKYHGFIRKSYE--LYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKY 136
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
LH + IHRD+ A N+LL D VK+ DFG++ V + W APE L
Sbjct 137 LHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSAL------TLAGTLNWMAPEIL 190
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
SD+WS G T+ E+LT +T + +E
Sbjct 191 GNRGASTLSDIWSLGATVVEMLTKNPP---------------YHNLTDANIYYAVENDTY 235
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P P + + C+ RPT + L+
Sbjct 236 YP-PSSFSEPLKDFLSKCFVKNMYKRPTADQLLK 268
Score = 199 bits (505), Expect = 9e-51, Method: Composition-based stats.
Identities = 57/304 (19%), Positives = 108/304 (36%), Gaps = 36/304 (12%)
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
+ A +NL+ + + +G+G+ VY+
Sbjct 2 NSMADTDRVNLTPIQRASEKSVQYHLKQVIGRGSYGVVYKAI------------------ 43
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685
++ + V +K + + + SL+ ++H ++ HG + E +
Sbjct 44 ------NKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYI 97
Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
+ EY +G L + R + Q L YL + ++H ++ NILL+
Sbjct 98 LLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSAD 157
Query 746 GLAEGTSPFIKLSDPGVGLGALSRE-ERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+KL+D GV S + W+APE L G ST D W GAT+
Sbjct 158 N-------TVKLADFGVSTIVNSSALTLAGTLNWMAPEIL--GNRGASTLSDIWSLGATV 208
Query 805 LEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
+E+ P + + + + + P L S+C +RP+ +L
Sbjct 209 VEMLTK-NPPYHNLTDANIYYAVENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLL 267
Query 864 RDLT 867
+ +
Sbjct 268 KHVW 271
>sp|P09560|RAF1_XENLA RAF proto-oncogene serine/threonine-protein
kinase OS=Xenopus laevis OX=8355 GN=raf1 PE=2 SV=1
Length=638
Score = 221 bits (563), Expect = 8e-60, Method: Composition-based stats.
Identities = 77/297 (26%), Positives = 130/297 (44%), Gaps = 27/297 (9%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHR 941
+S + +G G FG V + VAVK LK D P+
Sbjct 326 QRDSSYYWEIIASEVMLSSRIGSGSFGTVYKGKWHG-------DVAVKILKVTDPTPEQL 378
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQ 999
++ E+ +LR H +I+ + G + +L +V ++ SL +L + Q
Sbjct 379 QAFRNEVAVLRKTRHVNILLFMGYM---TKDNLAIVTQWCEGSSLYYHLHVLDTKFQMFQ 435
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
L+ A+Q +GM YLHA++ IHRD+ + N+ L VKIGDFGLA +V E
Sbjct 436 LIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKTRWSGSQQV-E 494
Query 1060 DGDSPVFWYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
+ W APE ++ F + SDV+S+G+ LYEL+T + + + +
Sbjct 495 QLTGSILWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHIRDRDQIIFLVGR 554
Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
G + V L++L + CP + L+ + + RP F ++ ++ +
Sbjct 555 GGV-VPDLSKLYK---------NCPKAMKRLVADSIKKLRDERPLFPQILSSIELLQ 601
Score = 211 bits (538), Expect = 1e-56, Method: Composition-based stats.
Identities = 63/310 (20%), Positives = 108/310 (35%), Gaps = 57/310 (18%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
R G+ N I RG R S + + E+ S +G G+ VY+G+
Sbjct 307 REKAASSTGQEKNKIRARGQRDSSY--------YWEIIASEVMLSSRIGSGSFGTVYKGK 358
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH--DIALAFYETASLMSQV 665
+ V +K+L + + AF +++ +
Sbjct 359 WHGD---------------------------VAVKILKVTDPTPEQLQAFRNEVAVLRKT 391
Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL 725
H ++ G + +VT++ E L L M + +A+Q A + YL
Sbjct 392 RHVNILLFMGYMTK-DNLAIVTQWCEGSSLYYHLHVLDTKFQMFQLIDIARQTAQGMDYL 450
Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWL 779
KN++H ++ NI L +K+ D G+ G+ E+ I W+
Sbjct 451 HAKNIIHRDMKSNNIFLHEGL-------TVKIGDFGLATVKTRWSGSQQVEQLTGSILWM 503
Query 780 APECLPGGA-NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838
APE + N S D + +G L E+ GE P ++ F +
Sbjct 504 APEVIRMQDNNPFSFQSDVYSYGIVLYELM-TGELPYSHIRDRDQIIFLVGRG----GVV 558
Query 839 PQLATLTSQC 848
P L+ L C
Sbjct 559 PDLSKLYKNC 568
>sp|Q9LMN8|WAK3_ARATH Wall-associated receptor kinase 3 OS=Arabidopsis
thaliana OX=3702 GN=WAK3 PE=2 SV=2
Length=741
Score = 223 bits (568), Expect = 9e-60, Method: Composition-based stats.
Identities = 78/344 (23%), Positives = 133/344 (39%), Gaps = 24/344 (7%)
Query 844 LTSQCLTYEPTQRPSFRTILRDLTR------LQPHNLADVLTVNPDSPASDPTVFHKRYL 897
L + C+ + QR + + + +Q + A + ++ +
Sbjct 356 LAAICIQHATKQRKYTKLRRQFFEQNGGGMLIQRLSGAGLSNIDFKIFTEEGMKEATNGY 415
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+ R LG+G G V +VA+K + + + E+ +L + H
Sbjct 416 DESRILGQGGQGTVYKGIL-----PDNTIVAIKKARL-ADSRQVDQFIHEVLVLSQINHR 469
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAY 1013
+++K GCC + E L LV E++ G+L D+L S+ L A ++ +AY
Sbjct 470 NVVKILGCCLE-TEVPL-LVYEFITNGTLFDHLHGSIFDSSLTWEHRLRIAIEVAGTLAY 527
Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
LH+ IHRD+ N+LLD + K+ DFG +K +P E G + + P
Sbjct 528 LHSSASIPIIHRDIKTANILLDENLTAKVADFGASKLIPMDKEQLTTMVQG--TLGYLDP 585
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E SDV+SFGV L ELL+ + P L+ RL E+++
Sbjct 586 EYYTTGLLNEKSDVYSFGVVLMELLSGQKALCFERPQASKHLVSYFVSATEENRLHEIID 645
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
K E + C RP + + L+ +
Sbjct 646 DQVLNEDNLKEIQEAARIAAECTRLMGEERPRMKEVAAKLEALR 689
Score = 202 bits (514), Expect = 7e-53, Method: Composition-based stats.
Identities = 68/387 (18%), Positives = 128/387 (33%), Gaps = 61/387 (16%)
Query 547 LRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606
LRR Q G + + GA S + + + LGQG + VY+G
Sbjct 373 LRRQFFEQNGGGMLIQRLSGAGLSNIDFKIFTEEGMKEATNGYDESRILGQGGQGTVYKG 432
Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS 666
L V +K + F ++SQ++
Sbjct 433 ILPDN-------------------------TIVAIKKARLADSRQVDQFIHEVLVLSQIN 467
Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE--RGHVPMAWKMVVAQQLASALSY 724
H ++ + G C+ ++V E++ +G L L + ++ +A ++A L+Y
Sbjct 468 HRNVVKILGCCLETEVPLLVYEFITNGTLFDHLHGSIFDSSLTWEHRLRIAIEVAGTLAY 527
Query 725 LENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERI 776
L + ++H ++ NILL + K++D G +E++ +
Sbjct 528 LHSSASIPIIHRDIKTANILLDE-------NLTAKVADFGASKLIPMDKEQLTTMVQGTL 580
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-----RQH 831
+L PE G L+ D + FG L+E+ +A R + K ++
Sbjct 581 GYLDPEYYTTGL--LNEKSDVYSFGVVLMELLSGQKALCFERPQASKHLVSYFVSATEEN 638
Query 832 RLPEPSCPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
RL E Q+ A + ++C +RP + + L L+ +
Sbjct 639 RLHEIIDDQVLNEDNLKEIQEAARIAAECTRLMGEERPRMKEVAAKLEALRVEKTKHKWS 698
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEG 906
H + G
Sbjct 699 DQYPEENEHLIGGHILSAQGETSSSIG 725
>sp|Q68UT7|HUNK_PANTR Hormonally up-regulated neu tumor-associated
kinase OS=Pan troglodytes OX=9598 GN=HUNK PE=3 SV=1
Length=714
Score = 223 bits (567), Expect = 9e-60, Method: Composition-based stats.
Identities = 75/306 (25%), Positives = 121/306 (40%), Gaps = 25/306 (8%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
YL R LGEG F KV + + TGE VA+K + +
Sbjct 45 PRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVR----EGLHVLTGEKVAIKVIDKKRAKK 100
Query 940 HR---SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSI 995
++E I + + H +I + E E S LVME P G+L + + +
Sbjct 101 DTYVTKNLRREGQIQQMIRHPNITQLLDILE--TENSYYLVMELCPGGNLMHKIYEKKRL 158
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
++ + +Q+ + +LH +HRDL N+LLD D +K+ DFGL+
Sbjct 159 EESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSD 218
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
SP + APE L K+ DVWS GV +Y +LT P
Sbjct 219 PFSTQCGSPA-YAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPF--------- 268
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
++ L + + E P P + +++ E + RP + + + ++E
Sbjct 269 ----SLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALAN-RWLNEN 323
Query 1176 YQGQAP 1181
Y G+ P
Sbjct 324 YTGKVP 329
Score = 162 bits (410), Expect = 7e-40, Method: Composition-based stats.
Identities = 58/344 (17%), Positives = 106/344 (31%), Gaps = 49/344 (14%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L H+ + LG+G+ V EG + G
Sbjct 49 LRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGE---------------------- 86
Query 636 ELRVVLKVLDPSHHD----IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+V +KV+D + + + H ++ + + +V E
Sbjct 87 --KVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCP 144
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G L + E+ + + +QL SA+ +L +VH ++ N+LL
Sbjct 145 GGNLMHKIY-EKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDN----- 198
Query 752 SPFIKLSDPGV----GLGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
IKL D G+ G+ S + + APE L +D W G +
Sbjct 199 --NIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA--RKKYGPKIDVWSIGVNMY 254
Query 806 EICFDGEAPL----QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861
+ G P S ++ + + LP + L +P +RP+ +
Sbjct 255 AML-TGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQ 313
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
L + + + V + S + L LG
Sbjct 314 ALANRWLNENYTGKVPCNVTYPNRISLEDLSPSVVLHMTEKLGY 357
>sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo
sapiens OX=9606 GN=SIK2 PE=1 SV=1
Length=926
Score = 226 bits (576), Expect = 9e-60, Method: Composition-based stats.
Identities = 72/291 (25%), Positives = 112/291 (38%), Gaps = 29/291 (10%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADC 936
+ + + LG+G+F V L + T VA+K + K+
Sbjct 1 MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLG----RHRITKTEVAIKIIDKSQL 56
Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SI 995
+ +E+ I++ L H HIIK E + L LV EY G + DYL H +
Sbjct 57 DAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKS--MLYLVTEYAKNGEIFDYLANHGRL 114
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
++ QI + Y H + +HRDL A N+LLDN+ +KI DFG G
Sbjct 115 NESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGE--- 171
Query 1056 RVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ + APE + ++ D+WS GV LY L+ P
Sbjct 172 -LLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGP---------- 220
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
T+ L + + G R P + HL++ + S R T +
Sbjct 221 -----TLPILRQRVLEG-RFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQI 265
Score = 195 bits (496), Expect = 8e-50, Method: Composition-based stats.
Identities = 64/323 (20%), Positives = 110/323 (34%), Gaps = 43/323 (13%)
Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
PR L + RV +I LG+G V GR R+
Sbjct 7 PRHLQRGPV---RVGFYDIE--GTLGKGNFAVVKLGRHRI-------------------- 41
Query 631 RDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+ V +K++D S D Y +M + H H+ ++ V +VTE
Sbjct 42 ----TKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTE 97
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
Y ++G + +L G + + Q+ SA+ Y + +VH ++ N+LL
Sbjct 98 YAKNGEIFDYLANH-GRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDN---- 152
Query 749 EGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ IK++D G G S E P+ APE G +D W G L
Sbjct 153 ---NMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYE-GPQLDIWSMGVVLY 208
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ P ++ + + R+P L + L +P++R + I
Sbjct 209 VLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEH 268
Query 866 LTRLQPHNLADVLTVNPDSPASD 888
L + + +
Sbjct 269 KWMLIEVPVQRPVLYPQEQENEP 291
>sp|P57058|HUNK_HUMAN Hormonally up-regulated neu tumor-associated
kinase OS=Homo sapiens OX=9606 GN=HUNK PE=1 SV=1
Length=714
Score = 223 bits (567), Expect = 9e-60, Method: Composition-based stats.
Identities = 75/306 (25%), Positives = 121/306 (40%), Gaps = 25/306 (8%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
YL R LGEG F KV + + TGE VA+K + +
Sbjct 45 PRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVR----EGLHVLTGEKVAIKVIDKKRAKK 100
Query 940 HR---SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSI 995
++E I + + H +I + E E S LVME P G+L + + +
Sbjct 101 DTYVTKNLRREGQIQQMIRHPNITQLLDILE--TENSYYLVMELCPGGNLMHKIYEKKRL 158
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
++ + +Q+ + +LH +HRDL N+LLD D +K+ DFGL+
Sbjct 159 EESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSD 218
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
SP + APE L K+ DVWS GV +Y +LT P
Sbjct 219 PFSTQCGSPA-YAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPF--------- 268
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175
++ L + + E P P + +++ E + RP + + + ++E
Sbjct 269 ----SLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALAN-RWLNEN 323
Query 1176 YQGQAP 1181
Y G+ P
Sbjct 324 YTGKVP 329
Score = 162 bits (410), Expect = 7e-40, Method: Composition-based stats.
Identities = 58/344 (17%), Positives = 106/344 (31%), Gaps = 49/344 (14%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L H+ + LG+G+ V EG + G
Sbjct 49 LRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGE---------------------- 86
Query 636 ELRVVLKVLDPSHHD----IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+V +KV+D + + + H ++ + + +V E
Sbjct 87 --KVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCP 144
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G L + E+ + + +QL SA+ +L +VH ++ N+LL
Sbjct 145 GGNLMHKIY-EKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDN----- 198
Query 752 SPFIKLSDPGV----GLGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
IKL D G+ G+ S + + APE L +D W G +
Sbjct 199 --NIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA--RKKYGPKIDVWSIGVNMY 254
Query 806 EICFDGEAPL----QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861
+ G P S ++ + + LP + L +P +RP+ +
Sbjct 255 AML-TGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQ 313
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
L + + + V + S + L LG
Sbjct 314 ALANRWLNENYTGKVPCNVTYPNRISLEDLSPSVVLHMTEKLGY 357
>sp|Q8NJT7|HOG1_HORWE Mitogen-activated protein kinase HOG1 OS=Hortaea
werneckii OX=91943 GN=HOG1 PE=3 SV=1
Length=359
Score = 213 bits (541), Expect = 9e-60, Method: Composition-based stats.
Identities = 66/276 (24%), Positives = 108/276 (39%), Gaps = 29/276 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VAVK + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SAKDQLTSQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + +V E + L L + + F QI G+ Y+H+
Sbjct 80 ICLSDIFISPLED-MYVVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIATICSENTLRFVQ 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFR 1159
L + ER P + + L++ + R
Sbjct 252 SLPKRERQPLKNKFKNADPQAIELLERMLVFDPRKR 287
Score = 134 bits (336), Expect = 1e-32, Method: Composition-based stats.
Identities = 41/252 (16%), Positives = 83/252 (33%), Gaps = 21/252 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + +D+ V +K ++ P ++ Y
Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSAKDQLTSQAVAVKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + +VTE + L L + +
Sbjct 67 ELKLLKHLRHENIICLSDIFISPLEDMYVVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
+ APE + +D W G E+ +G+ + F L
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDH--VNQFSIITELLGT 232
Query 836 PSCPQLATLTSQ 847
P +AT+ S+
Sbjct 233 PPDDVIATICSE 244
>sp|Q63572|TESK1_RAT Dual specificity testis-specific protein
kinase 1 OS=Rattus norvegicus OX=10116 GN=Tesk1 PE=1 SV=1
Length=628
Score = 220 bits (561), Expect = 1e-59, Method: Composition-based stats.
Identities = 73/290 (25%), Positives = 123/290 (42%), Gaps = 28/290 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+G G F +V Y + +G+++ LK + P +RS +E+ ++ L H
Sbjct 52 FDCAEKIGAGFFSEV----YKVRHRQSGQVM---VLKMNKLPSNRSNTLREVQLMNRLRH 104
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLH 1015
+I+++ G C QG+ L + EY+ G+L L + L A I +G+ YLH
Sbjct 105 PNILRFMGVCVHQGQ--LHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIAQGLRYLH 162
Query 1016 AQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVRE-DGDSPVFWYAPE 1071
A+ HRDL ++N L+ D +GDFGLA+ +P E R +W APE
Sbjct 163 AKGVFHRDLTSKNCLVRREDGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPE 222
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
L+ + +DV++FG+ L EL+ + + + T++
Sbjct 223 VLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVG-------- 274
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
+ CP L +C E S R F + L+ + E+ P
Sbjct 275 ------NDCPLPFLLLAIHCCSMEPSARAPFTEITQHLEQILEQLPEPTP 318
Score = 192 bits (488), Expect = 3e-50, Method: Composition-based stats.
Identities = 69/311 (22%), Positives = 113/311 (36%), Gaps = 45/311 (14%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
+S R L + S RVD + +G G + VY+ R R G
Sbjct 34 SSYRALRSAVSSLARVD--DFDCAEKIGAGFFSEVYKVRHRQSG---------------- 75
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+V++ ++ + + LM+++ H ++ GVCV + +TE
Sbjct 76 ---------QVMVLKMNKLPSNRSNT-LREVQLMNRLRHPNILRFMGVCVHQGQLHALTE 125
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
Y+ G L+ L + ++ +A +A L YL K + H ++ +N L+ R
Sbjct 126 YMNGGTLEQLLSSPE-PLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRR---- 180
Query 749 EGTSPFIKLSDPGVG-LGALSREER-------VERIPWLAPECLPGGANSLSTAMDKWGF 800
E + D G+ + RE V W+APE L G D + F
Sbjct 181 EDGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGEL--YDEKADVFAF 238
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-LPEPSCP-QLATLTSQCLTYEPTQRPS 858
G L E+ A +E R L CP L C + EP+ R
Sbjct 239 GIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSARAP 298
Query 859 FRTILRDLTRL 869
F I + L ++
Sbjct 299 FTEITQHLEQI 309
>sp|P0CP68|HOG1_CRYNJ Mitogen-activated protein kinase HOG1 OS=Cryptococcus
neoformans var. neoformans serotype D (strain
JEC21 / ATCC MYA-565) OX=214684 GN=HOG1 PE=1 SV=1
Length=365
Score = 213 bits (541), Expect = 1e-59, Method: Composition-based stats.
Identities = 64/282 (23%), Positives = 106/282 (38%), Gaps = 31/282 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + +G VA+K + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SAKDQLSGTSVAIKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGIAQGQMTVL 1122
A D+WS G E+L +PP ++ I V
Sbjct 192 DVAVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTIASENTLRFVQ 251
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
L + + P+ P + L++ + R +
Sbjct 252 SLPKREKVPFSTKFPNADPVSL-DLLEKMLVFDPRTRISAAE 292
Score = 139 bits (349), Expect = 3e-34, Method: Composition-based stats.
Identities = 37/231 (16%), Positives = 77/231 (33%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
V+E D + M + +D+ V +K ++ P ++ Y
Sbjct 10 FGTVFE---VTTRYVDLQPVGMGAFGLVCSAKDQLSGTSVAIKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + A+D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVAVDIWSTGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q56R42|HOG1_CRYNH Mitogen-activated protein kinase HOG1 OS=Cryptococcus
neoformans var. grubii serotype A (strain H99
/ ATCC 208821 / CBS 10515 / FGSC 9487) OX=235443 GN=HOG1 PE=1
SV=1
Length=365
Score = 213 bits (541), Expect = 1e-59, Method: Composition-based stats.
Identities = 64/282 (23%), Positives = 106/282 (38%), Gaps = 31/282 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + +G VA+K + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SAKDQLSGTSVAIKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGIAQGQMTVL 1122
A D+WS G E+L +PP ++ I V
Sbjct 192 DVAVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTIASENTLRFVQ 251
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
L + + P+ P + L++ + R +
Sbjct 252 SLPKREKVPFSTKFPNADPVSL-DLLEKMLVFDPRTRISAAE 292
Score = 139 bits (349), Expect = 3e-34, Method: Composition-based stats.
Identities = 37/231 (16%), Positives = 77/231 (33%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
V+E D + M + +D+ V +K ++ P ++ Y
Sbjct 10 FGTVFE---VTTRYVDLQPVGMGAFGLVCSAKDQLSGTSVAIKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + A+D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVAVDIWSTGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|P0CP69|HOG1_CRYNB Mitogen-activated protein kinase HOG1 OS=Cryptococcus
neoformans var. neoformans serotype D (strain
B-3501A) OX=283643 GN=HOG1 PE=3 SV=1
Length=365
Score = 213 bits (541), Expect = 1e-59, Method: Composition-based stats.
Identities = 64/282 (23%), Positives = 106/282 (38%), Gaps = 31/282 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + +G VA+K + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SAKDQLSGTSVAIKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGIAQGQMTVL 1122
A D+WS G E+L +PP ++ I V
Sbjct 192 DVAVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTIASENTLRFVQ 251
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
L + + P+ P + L++ + R +
Sbjct 252 SLPKREKVPFSTKFPNADPVSL-DLLEKMLVFDPRTRISAAE 292
Score = 139 bits (349), Expect = 3e-34, Method: Composition-based stats.
Identities = 37/231 (16%), Positives = 77/231 (33%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
V+E D + M + +D+ V +K ++ P ++ Y
Sbjct 10 FGTVFE---VTTRYVDLQPVGMGAFGLVCSAKDQLSGTSVAIKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + A+D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVAVDIWSTGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q13546|RIPK1_HUMAN Receptor-interacting serine/threonine-protein
kinase 1 OS=Homo sapiens OX=9606 GN=RIPK1 PE=1 SV=3
Length=671
Score = 221 bits (564), Expect = 1e-59, Method: Composition-based stats.
Identities = 81/289 (28%), Positives = 124/289 (43%), Gaps = 38/289 (13%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG-PQHRSGWKQEIDILRTLYHEHII 960
+L G FGKVSL + T ++ +K + +H +E ++ L H ++
Sbjct 22 ELDSGGFGKVSLCFHR-----TQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVV 76
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
K G ++G+ S LVMEY+ G+L L S L+ +I EGM YLH +
Sbjct 77 KLLGVIIEEGKYS--LVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMCYLHGKGV 134
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKA----------VPEGHEYYRVREDGDSPVFWYA 1069
IH+DL N+L+DND +KI D GLA E E + +++ A
Sbjct 135 IHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMA 194
Query 1070 PECLKE--YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
PE L + K SDV+SF V L+ + + + + + +L
Sbjct 195 PEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPY--------------ENAICEQQLIMC 240
Query 1128 LERGERLPRPD---KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
++ G R D CP E+ LMK CWE RPTF + + +
Sbjct 241 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFY 289
Score = 189 bits (480), Expect = 7e-49, Method: Composition-based stats.
Identities = 53/315 (17%), Positives = 108/315 (34%), Gaps = 53/315 (17%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
L+ ++ + + + L G V R +G +
Sbjct 6 SLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKG--------------- 50
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
P+ + A E A +M+++ H+ + + GV + + +V EY+E G L
Sbjct 51 --------PNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMH 102
Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
L+ E P++ K + ++ + YL K ++H ++ NIL+ IK+
Sbjct 103 VLKAEM-STPLSVKGRIILEIIEGMCYLHGKGVIHKDLKPENILVDN-------DFHIKI 154
Query 758 SDPGVGLGAL-----------------SREERVERIPWLAPECLPGGANSLSTAMDKWGF 800
+D G+ + + ++ + ++APE L + D + F
Sbjct 155 ADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSF 214
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-----LPEPSCPQLATLTSQCLTYEPTQ 855
L I + E + + + +R + E ++ +L C P
Sbjct 215 AVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEYCPREIISLMKLCWEANPEA 274
Query 856 RPSFRTILRDLTRLQ 870
RP+F I
Sbjct 275 RPTFPGIEEKFRPFY 289
>sp|F1NBT0|STK10_CHICK Serine/threonine-protein kinase 10 OS=Gallus
gallus OX=9031 GN=STK10 PE=3 SV=2
Length=969
Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats.
Identities = 74/299 (25%), Positives = 127/299 (42%), Gaps = 30/299 (10%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935
+ + + + + +LG+G FGKV Y N TG + A K ++
Sbjct 15 FEKRRSKEYEHVRRDLDPGEVWEVVGELGDGAFGKV----YKAKNKETGALAAAKVIETK 70
Query 936 CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--H 993
+ EI+IL T H HI+K G +G+ L +++E+ P G++ +
Sbjct 71 -NEDELEDYMVEIEILATCDHPHIVKLLGAFYWEGK--LWIMIEFCPGGAVDATMLELDR 127
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ Q+ + +Q+ E + YLH++ IHRDL A NVLL D +K+ DFG++ + +
Sbjct 128 GLTEPQIQVICRQMLEALHYLHSKKIIHRDLKAGNVLLTQDGDIKLADFGVS---AKNVK 184
Query 1054 YYRVREDGDSPVFWYAPEC-----LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
+ R+ +W APE +K+ + Y +D+WS G+TL E+ +
Sbjct 185 TLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMA-QIEPPHHELNPM 243
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L+ IA+ L P K E +K + RP+ L+
Sbjct 244 RVLLKIAKSDPPT------------LSCPSKWSLEFRDFLKTALDKNPETRPSAAQLLE 290
Score = 184 bits (467), Expect = 3e-46, Method: Composition-based stats.
Identities = 54/285 (19%), Positives = 95/285 (33%), Gaps = 43/285 (15%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LG G VY+ + + G+ KV++ + D
Sbjct 41 ELGDGAFGKVYKAKNKETGA------------------------LAAAKVIETKNEDELE 76
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
+ +++ H H+ + G + ++ E+ G +D + + V
Sbjct 77 DYMVEIEILATCDHPHIVKLLGAFYWEGKLWIMIEFCPGGAVDATMLELDRGLTEPQIQV 136
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGALSR 769
+ +Q+ AL YL +K ++H ++ N+LL + G IKL+D GV R
Sbjct 137 ICRQMLEALHYLHSKKIIHRDLKAGNVLLTQDGD-------IKLADFGVSAKNVKTLQKR 189
Query 770 EERVERIPWLAPECLP---GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ + W+APE + D W G TL+E+ E P +P
Sbjct 190 DSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMA-QIEPPHHELNPMRVLLK 248
Query 827 YQRQHR----LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P + L P RPS +L
Sbjct 249 IAKSDPPTLSCPSKWSLEFRDFLKTALDKNPETRPSAAQLLEHPF 293
>sp|Q8LPS5|SERK5_ARATH Somatic embryogenesis receptor kinase 5
OS=Arabidopsis thaliana OX=3702 GN=SERK5 PE=1 SV=2
Length=601
Score = 219 bits (559), Expect = 1e-59, Method: Composition-based stats.
Identities = 67/323 (21%), Positives = 123/323 (38%), Gaps = 20/323 (6%)
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918
R + + +V + + K LG+G FG +
Sbjct 237 RRKLQGHFLDVPAEEDPEVYLGQFKRFSLRELLVATEKFSKRNVLGKGRFGILYKGRL-- 294
Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978
+VAVK L + ++ E++++ H ++++ +G C E+ LV
Sbjct 295 ---ADDTLVAVKRLNEERTKGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTER--LLVY 349
Query 979 EYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVL 1030
Y+ GS+ L + + A G+AYLH IH D+ A N+L
Sbjct 350 PYMANGSVASCLRERPEGNPALDWPKRKHIALGSARGLAYLHDHCDQKIIHLDVKAANIL 409
Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
LD + +GDFGLAK + + V + APE L K +DV+ +GV
Sbjct 410 LDEEFEAVVGDFGLAKLMNYNDSH--VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGVM 467
Query 1091 LYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
L EL+T + + + L+ + + +L L++ + ++ +
Sbjct 468 LLELITGQKAFDLARLANDDDIMLLDWVKEVLKEKKLESLVDAELEGKYVETEVEQLIQM 527
Query 1148 MKNCWETEASFRPTFENLIPILK 1170
C ++ A RP ++ +L+
Sbjct 528 ALLCTQSSAMERPKMSEVVRMLE 550
Score = 181 bits (459), Expect = 1e-46, Method: Composition-based stats.
Identities = 68/352 (19%), Positives = 129/352 (37%), Gaps = 52/352 (15%)
Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
+ S V ++ ++ + LG+G +Y+GRL
Sbjct 259 QFKRFSLRELLVATEKFSKRNVLGKGRFGILYKGRL------------------------ 294
Query 633 RGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+ V +K L+ L F ++S H +L + G C+ E ++V Y+
Sbjct 295 -ADDTLVAVKRLNEERTKGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMA 353
Query 692 HGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARL 745
+G + LR R G+ + W + +A A L+YL ++ ++H +V NILL
Sbjct 354 NGSVASCLRERPEGNPALDWPKRKHIALGSARGLAYLHDHCDQKIIHLDVKAANILLDEE 413
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800
A + D G+ + V I +APE L G + S D +G+
Sbjct 414 FEAV-------VGDFGLAKLMNYNDSHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 464
Query 801 GATLLEICFDGEAPLQSR--SPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQR 856
G LLE+ +A +R + + + L E L A L + + E Q
Sbjct 465 GVMLLELITGQKAFDLARLANDDDIMLLDWVKEVLKEKKLESLVDAELEGKYVETEVEQL 524
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
+ + ++ +++V+ + ++ ++ I D +
Sbjct 525 IQMALLCTQSSAMERPKMSEVVRMLEGDGLAERWEEWQKEEMPIHDFNYQAY 576
>sp|Q641K5|NUAK1_MOUSE NUAK family SNF1-like kinase 1 OS=Mus musculus
OX=10090 GN=Nuak1 PE=1 SV=1
Length=658
Score = 221 bits (563), Expect = 1e-59, Method: Composition-based stats.
Identities = 67/292 (23%), Positives = 113/292 (39%), Gaps = 31/292 (11%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937
K + LG+G +GKV T +G +VA+K+++ D
Sbjct 37 PRKPHGVKRHHHKHNLKHRYELQETLGKGTYGKVK----RATERFSGRVVAIKSIRKDKI 92
Query 938 PQHRS--GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHS 994
++EI+I+ +L H HII E++ + + ++MEY G L DY+ R
Sbjct 93 KDELDMVHIRREIEIMSSLNHPHIISIYEVFENKDK--IVIIMEYASKGELYDYISERRR 150
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ + F +QI + Y H +HRDL N+LLD++ +KI DFGL+ +
Sbjct 151 LSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKD--- 207
Query 1055 YRVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
+ + + +PE + + D W+ GV LY L+
Sbjct 208 -KFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLIYGTMPFD----------- 255
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L + GE R P + L++ R T E++
Sbjct 256 ----GFDHKNLIRQISSGEY--REPTQPSDARGLIRWMLMVNPDRRATIEDI 301
Score = 167 bits (422), Expect = 1e-41, Method: Composition-based stats.
Identities = 51/321 (16%), Positives = 89/321 (28%), Gaps = 40/321 (12%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
LG+GT V R G V +K +
Sbjct 57 ELQETLGKGTYGKVKRATERFSGR------------------------VVAIKSIRKDKI 92
Query 650 DIALA---FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
L +MS ++H H+ ++ V + +++ EY G L ++ ER +
Sbjct 93 KDELDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYI-SERRRL 151
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+Q+ SA+ Y +VH ++ NILL + IK++D G+
Sbjct 152 SERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLD-------DNCNIKIADFGLSNLY 204
Query 767 LSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ + +PE + G +D W G L + G P
Sbjct 205 QKDKFLQTFCGSPLYASPEIVNGRPYR-GPEVDSWALGVLLYTLI-YGTMPFDGFDHKNL 262
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
L L P +R + I + +
Sbjct 263 IRQISSGEYREPTQPSDARGLIRWMLMVNPDRRATIEDIANHWWVNWGYKSSVCDCDALP 322
Query 884 SPASDPTVFHKRYLKKIRDLG 904
S + + L
Sbjct 323 DSESPLLARIIDWHHRSTGLQ 343
>sp|P28178|PK2_DICDI Protein kinase 2 OS=Dictyostelium discoideum
OX=44689 GN=pkgB PE=1 SV=2
Length=479
Score = 216 bits (551), Expect = 1e-59, Method: Composition-based stats.
Identities = 66/260 (25%), Positives = 107/260 (41%), Gaps = 29/260 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960
+G+G FGKV + + A+K L+ D + + K E IL+ + H I+
Sbjct 159 IGKGSFGKVMQVKKKGEDK----IFAMKVLRKDAIIARKQVNHTKSEKTILQCISHPFIV 214
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHY 1019
Q + L +V+++V G L +L R ++ ++A +I + +LH Q
Sbjct 215 NLHYAF--QTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALDHLHKQDI 272
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
++RDL N+LLD++ + I DFGL+K + + + APE L +
Sbjct 273 VYRDLKPENILLDSEGHICITDFGLSKKIETTDGTFT----FCGTPEYLAPEVLNGHGHG 328
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
A D WS G LYE+LT S V + + + GE L P
Sbjct 329 CAVDWWSLGTLLYEMLTGLPPFYSQ---------------NVSTMYQKILNGE-LKIPTY 372
Query 1140 CPCEVYHLMKNCWETEASFR 1159
E L++ E R
Sbjct 373 ISPEAKSLLEGLLTREVDKR 392
Score = 169 bits (429), Expect = 1e-43, Method: Composition-based stats.
Identities = 56/271 (21%), Positives = 108/271 (40%), Gaps = 36/271 (13%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ + L+ +G+G+ V + K ED + + ++ + K ++
Sbjct 150 KDDFELLNVIGKGSFGKV-------------MQVKKKGEDKIFAMKVLRKDAIIARKQVN 196
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ +++ +SH + +H + MV ++V G L L+RE G
Sbjct 197 HTKS--------EKTILQCISHPFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLKRE-GR 247
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+ A ++ SAL +L +++V+ ++ NILL G I ++D G+
Sbjct 248 FSEPRVKIYAAEIVSALDHLHKQDIVYRDLKPENILLDSEG-------HICITDFGLSKK 300
Query 766 ALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS- 821
+ + +LAPE L G + A+D W G L E+ G P S++ S
Sbjct 301 IETTDGTFTFCGTPEYLAPEVLNG--HGHGCAVDWWSLGTLLYEML-TGLPPFYSQNVST 357
Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYE 852
+ + ++P P+ +L LT E
Sbjct 358 MYQKILNGELKIPTYISPEAKSLLEGLLTRE 388
>sp|Q5EG47|AAPK1_MOUSE 5'-AMP-activated protein kinase catalytic
subunit alpha-1 OS=Mus musculus OX=10090 GN=Prkaa1 PE=1 SV=2
Length=559
Score = 218 bits (556), Expect = 1e-59, Method: Composition-based stats.
Identities = 76/274 (28%), Positives = 110/274 (40%), Gaps = 30/274 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953
+ LG G FGKV + ++ TG VAVK L ++EI L+
Sbjct 26 HYILGDTLGVGTFGKVKVG----KHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKL 81
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012
H HIIK + + +VMEYV G L DY+ ++ + + QQI G+
Sbjct 82 FRHPHIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVD 139
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE
Sbjct 140 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 195
Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + D+WS GV LY LL V L + + G
Sbjct 196 ISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDH---------------VPTLFKKICDG 240
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P V L+K+ + + R +++
Sbjct 241 IFYT-PQYLNPSVISLLKHMLQVDPMKRAAIKDI 273
Score = 182 bits (463), Expect = 2e-47, Method: Composition-based stats.
Identities = 54/298 (18%), Positives = 94/298 (32%), Gaps = 39/298 (13%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
Q RV LG GT V G+ + G
Sbjct 15 KQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGH----------------------- 51
Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+V +K+L+ D+ + H H+ ++ V + MV EYV G
Sbjct 52 -KVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGG 110
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L ++ + G + + QQ+ S + Y +VH ++ N+LL
Sbjct 111 ELFDYICKN-GRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD-------AHM 162
Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ E + APE + G + +D W G L +
Sbjct 163 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSSGVILYALLCG 221
Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
P+ + P+ P + +L L +P +R + + I
Sbjct 222 TLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIKDIREHEWF 279
>sp|Q75L42|CIPKH_ORYSJ CBL-interacting protein kinase 17 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK17 PE=2 SV=1
Length=454
Score = 216 bits (549), Expect = 1e-59, Method: Composition-based stats.
Identities = 67/273 (25%), Positives = 112/273 (41%), Gaps = 27/273 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTL 954
+ R LGEG+FGKV + TG AVK L R ++EI L+ L
Sbjct 13 YEMGRTLGEGNFGKVKY----ARHLATGGHFAVKILDRGRVVSLRAGDQIRREIATLKLL 68
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAY 1013
H H+++ + + + +V+E+V G L + + + + + QQ+ +G++Y
Sbjct 69 RHPHVVRLHEVAASKTK--IYMVLEFVNGGELFERIAVKGKLSEKEGRRLFQQLIDGVSY 126
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
H + HRDL NVL+D +KI DFGL+ + SP + APE L
Sbjct 127 CHDRGVYHRDLKPENVLVDQKGNIKISDFGLSALPQHLGNDGLLHTTCGSPN-YIAPEVL 185
Query 1074 KEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ + + SD+WS GV LY +L ++ L + + +G+
Sbjct 186 QNKGYDGSLSDIWSCGVILYVMLIGYLPFDD---------------RNIVVLYQKIFKGD 230
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P +L++ E R +
Sbjct 231 T-QIPKWLSHSAQNLLRRILEPNPMKRIDMAGI 262
Score = 171 bits (433), Expect = 2e-44, Method: Composition-based stats.
Identities = 51/300 (17%), Positives = 88/300 (29%), Gaps = 44/300 (15%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647
LG+G V R G +K+LD
Sbjct 14 EMGRTLGEGNFGKVKYARHLATGGHF------------------------AVKILDRGRV 49
Query 648 -HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
+ + + H H+ +H V + MV E+V G L + +G +
Sbjct 50 VSLRAGDQIRREIATLKLLRHPHVVRLHEVAASKTKIYMVLEFVNGGELFERI-AVKGKL 108
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ QQL +SY ++ + H ++ N+L+ + G IK+SD G+
Sbjct 109 SEKEGRRLFQQLIDGVSYCHDRGVYHRDLKPENVLVDQKG-------NIKISDFGLSALP 161
Query 767 LS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
++APE L + D W G L + G P R+
Sbjct 162 QHLGNDGLLHTTCGSPNYIAPEVLQNKGYD-GSLSDIWSCGVILYVMLI-GYLPFDDRNI 219
Query 821 SEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
+ +P+ L + L P +R I + +
Sbjct 220 VVLYQKIFKGDTQIPKWLSHSAQNLLRRILEPNPMKRIDMAGIKSHEWFQKDYIPVLPYD 279
>sp|Q9LSS0|LRK17_ARATH L-type lectin-domain containing receptor
kinase I.7 OS=Arabidopsis thaliana OX=3702 GN=LECRK17 PE=2
SV=1
Length=668
Score = 221 bits (563), Expect = 1e-59, Method: Composition-based stats.
Identities = 78/281 (28%), Positives = 117/281 (42%), Gaps = 16/281 (6%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+ LG G FG+V + + VAVK + D G + EI +R+L H
Sbjct 341 FNRSEFLGRGGFGEVYKGTLPRSREL--REVAVKRVSHD-GEHGMKQFVAEIVSMRSLKH 397
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAY 1013
++ G C + E L LV EY+P GSL YL H S+ + L + I ++Y
Sbjct 398 RSLVPLLGYCRRKHE--LLLVSEYMPNGSLDHYLFNHDRLSLPWWRRLAILRDIASALSY 455
Query 1014 LHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
LH + IHRD+ A NV+LD + ++GDFG+++ G + V + AP
Sbjct 456 LHTEADQVVIHRDIKAANVMLDAEFNGRLGDFGMSRLYDRGADPSTT--AAVGTVGYMAP 513
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E L +DV++FGV L E +T P + I R + + R
Sbjct 514 E-LTTMGASTGTDVYAFGVFLLE-VTCGRRPVEPGLPEAKRFLIKWVSECWKRSSLIDAR 571
Query 1131 GERL-PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
RL + +V L C RP E ++ L
Sbjct 572 DPRLTEFSSQEVEKVLKLGLLCANLAPDSRPAMEQVVQYLN 612
Score = 210 bits (535), Expect = 5e-56, Method: Composition-based stats.
Identities = 72/308 (23%), Positives = 118/308 (38%), Gaps = 61/308 (20%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR-VVLKV 643
K + LG+G VY+G L R +ELR V +K
Sbjct 337 ATKGFNRSEFLGRGGFGEVYKGTL-----------------------PRSRELREVAVKR 373
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702
+ F M + H L + G C R E ++V+EY+ +G LD +L
Sbjct 374 VSHDGEHGMKQFVAEIVSMRSLKHRSLVPLLGYCRRKHELLLVSEYMPNGSLDHYLFNHD 433
Query 703 RGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
R +P ++ + + +ASALSYL ++ ++H ++ N++L +L D
Sbjct 434 RLSLPWWRRLAILRDIASALSYLHTEADQVVIHRDIKAANVMLD-------AEFNGRLGD 486
Query 760 PGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ S V + ++APE GA ST D + FG LLE+ G P
Sbjct 487 FGMSRLYDRGADPSTTAAVGTVGYMAPELTTMGA---STGTDVYAFGVFLLEV-TCGRRP 542
Query 815 LQSRSPSEKEHF------YQRQHRLPEPSCPQLATLTSQ-----------CLTYEPTQRP 857
++ P K ++ L + P+L +SQ C P RP
Sbjct 543 VEPGLPEAKRFLIKWVSECWKRSSLIDARDPRLTEFSSQEVEKVLKLGLLCANLAPDSRP 602
Query 858 SFRTILRD 865
+ +++
Sbjct 603 AMEQVVQY 610
>sp|Q99ML2|TNK1_MOUSE Non-receptor tyrosine-protein kinase TNK1
OS=Mus musculus OX=10090 GN=Tnk1 PE=1 SV=2
Length=666
Score = 221 bits (563), Expect = 1e-59, Method: Composition-based stats.
Identities = 93/276 (34%), Positives = 133/276 (48%), Gaps = 24/276 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRS--GWKQEIDILRTLYHEHI 959
LG G FG V + G VAVK+L+ GP + +E+ ++ L H H+
Sbjct 122 LGSGCFGVVHRGLWT-LPSGQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHV 180
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLH 1015
++ G Q LQ+VME PLGSL L + +A L LF +Q+ MAYL
Sbjct 181 LRLHGLVLGQ---PLQMVMELAPLGSLHARLTAPAPTPPLPVALLCLFLRQLAGAMAYLG 237
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ +HRDLA RN+LL + R++K+ DFGL + + Y + P W APE L++
Sbjct 238 SCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRQ 297
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
F ASDVW FGVTL+E+ + + + G L L L + RLP
Sbjct 298 GAFSSASDVWMFGVTLWEMFSGGEEPWA-------------GVPPYLILQRLEKDRARLP 344
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
+P C +Y L CW + RP+F NL +L+
Sbjct 345 KPPLCSRALYSLALRCWAPHPADRPSFSNLEGLLQE 380
Score = 187 bits (476), Expect = 2e-48, Method: Composition-based stats.
Identities = 74/295 (25%), Positives = 112/295 (38%), Gaps = 47/295 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ + + + LG G V+ G GQ + V +K
Sbjct 111 IPEGAVRRGELLGSGCFGVVHRGLW---------------------TLPSGQSIPVAVKS 149
Query 644 LDPSHHDIAL----AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD--V 697
L F S+M ++ H H+ +HG+ + G MV E G L +
Sbjct 150 LRVGPEGPMGTELGDFLREVSVMMKLEHPHVLRLHGLVL-GQPLQMVMELAPLGSLHARL 208
Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+P+A + +QLA A++YL + LVH ++ RN+LLA + IK+
Sbjct 209 TAPAPTPPLPVALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLA-------SPRMIKV 261
Query 758 SDPGV------GLGAL-SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+D G+ G R W APE L GA S+A D W FG TL E+
Sbjct 262 ADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRQGA--FSSASDVWMFGVTLWEMFSG 319
Query 811 GEAPLQSRSP---SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
GE P P ++ + + P L +L +C P RPSF +
Sbjct 320 GEEPWAGVPPYLILQRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFSNL 374
>sp|Q6XKY3|HOG1_HYPAT Mitogen-activated protein kinase hog1 OS=Hypocrea
atroviridis OX=63577 GN=hog1 PE=3 SV=1
Length=357
Score = 212 bits (540), Expect = 1e-59, Method: Composition-based stats.
Identities = 66/283 (23%), Positives = 107/283 (38%), Gaps = 29/283 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VAVK L K P +E+ + + L HE++
Sbjct 24 QPVGMGAFGLVC----SARDQLTNQNVAVKKLMKPFSTPVLAKRTYRELKLFKHLRHENV 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTAY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L + ER P + L++ + R T +
Sbjct 252 SLPKRERQPLRNKFKNADDSAIDLLERMLVFDPKKRITATEAL 294
Score = 128 bits (321), Expect = 1e-30, Method: Composition-based stats.
Identities = 38/231 (16%), Positives = 73/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHD-IALAFYE 657
+E D + M + RD+ V +K L P +A Y
Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAVKKLMKPFSTPVLAKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLFKHLRHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTAYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q54WX4|AURK_DICDI Aurora kinase OS=Dictyostelium discoideum
OX=44689 GN=aurK PE=1 SV=1
Length=384
Score = 213 bits (543), Expect = 1e-59, Method: Composition-based stats.
Identities = 62/279 (22%), Positives = 109/279 (39%), Gaps = 30/279 (11%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEID 949
+ + LG G FG V L + +VA+K L + H ++EI+
Sbjct 105 WCIDDFDIGKLLGMGRFGHVYL----AREKKSQFIVALKVLFKNQLQTHNIEHQLRREIE 160
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQIC 1008
I L H +I++ G D +K + L++E+ G L + S + QI
Sbjct 161 IQSHLRHPNILRLFGYFYD--DKRVFLIIEFAKGGECFKELQKVGSFNEQTAATYTLQIA 218
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+ + Y H++H IHRD+ N+L+ +KI DFG + P R + +
Sbjct 219 DALRYCHSKHVIHRDIKPENLLIGVGGEIKIADFGWSVHAPN-----TKRSTFCGTLEYL 273
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE +++ + +DVWS G+ ++E L S K + I + +
Sbjct 274 PPEVIEKKGYDQTADVWSLGILIFEFLVGRSPFTSDEEKNI-FHNIQENDVY-------- 324
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P E L+ ++ R T +++I
Sbjct 325 -------YPSSISPEAKDLISRLLVSDPHQRITLKDVIN 356
Score = 185 bits (469), Expect = 8e-50, Method: Composition-based stats.
Identities = 56/312 (18%), Positives = 103/312 (33%), Gaps = 41/312 (13%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ LG G +VY R++ + V LKVL
Sbjct 108 DDFDIGKLLGMGRFGHVYLA------------------------REKKSQFIVALKVLFK 143
Query 647 SH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ H+I + S + H ++ + G ++ E+ + G L++
Sbjct 144 NQLQTHNIEHQLRREIEIQSHLRHPNILRLFGYFYDDKRVFLIIEFAKGGECFKELQKV- 202
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
G Q+A AL Y +K+++H ++ N+L+ G IK++D G
Sbjct 203 GSFNEQTAATYTLQIADALRYCHSKHVIHRDIKPENLLI-------GVGGEIKIADFGWS 255
Query 764 LGA--LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ A R + +L PE + D W G + E G +P S
Sbjct 256 VHAPNTKRSTFCGTLEYLPPEVIE--KKGYDQTADVWSLGILIFEFLV-GRSPFTSDEEK 312
Query 822 EKEH-FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880
H + P P+ L S+ L +P QR + + ++ + + +
Sbjct 313 NIFHNIQENDVYYPSSISPEAKDLISRLLVSDPHQRITLKDVINHPWIKKHAHPKSLEPT 372
Query 881 NPDSPASDPTVF 892
P +
Sbjct 373 KLGLPLPSQMTY 384
>sp|Q0D0P5|HOG1_ASPTN Mitogen-activated protein kinase hog1 OS=Aspergillus
terreus (strain NIH 2624 / FGSC A1156) OX=341663
GN=hog1 PE=3 SV=2
Length=364
Score = 213 bits (541), Expect = 1e-59, Method: Composition-based stats.
Identities = 66/283 (23%), Positives = 109/283 (39%), Gaps = 29/283 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + TG+ VAVK + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SAKDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
D+WS E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAACIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIRGICSENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L + ER P + + L++ ++ R +
Sbjct 252 SLPKRERQPLANKFKNADPDAIDLLERMLVFDSKKRIRAGEAL 294
Score = 131 bits (329), Expect = 1e-31, Method: Composition-based stats.
Identities = 34/231 (15%), Positives = 73/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + +D+ V +K ++ P ++ Y
Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSAKDQLTGQPVAVKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAACIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q9NGW9|MKCB_DICDI Probable serine/threonine-protein kinase
mkcB OS=Dictyostelium discoideum OX=44689 GN=mkcB PE=2 SV=1
Length=714
Score = 222 bits (566), Expect = 1e-59, Method: Composition-based stats.
Identities = 61/272 (22%), Positives = 109/272 (40%), Gaps = 25/272 (9%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
K +G+G FG V + +VA+K + Q + + +E IL
Sbjct 437 MYKDSDQVGKGGFGTVYF----AKSTKEKRLVAIKKMPHVTKRQQQQNF-REAAILAKCD 491
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH 1015
H +I+K C D+ + +L +VME++ G+ + L A+++ +G+ YLH
Sbjct 492 HPNIVKLHTCHIDK-DSNLWIVMEFMEGGTFEEAAKAWKFNENNLAYVAKELLKGLQYLH 550
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
H +HRDL + N+++ + VK+ DFGL + V + V FW APE +++
Sbjct 551 ENHMVHRDLKSANIMMSVEGKVKLIDFGLCEDVATSTPMHMV-----GSPFWMAPEMIQQ 605
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
D+WSF ++L E+ K + + +
Sbjct 606 KYHSTPVDIWSFAISLLEMANQRPPMMESAVKAMFTVAT--------------DGATGFD 651
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P + C + + + R T E L+
Sbjct 652 DPALWSDCFKDFLSLCLKQDPAERATAEELLK 683
Score = 179 bits (455), Expect = 2e-45, Method: Composition-based stats.
Identities = 49/281 (17%), Positives = 97/281 (35%), Gaps = 42/281 (15%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
+G+G VY + ++ V +K +
Sbjct 442 DQVGKGGFGTVY------------------------FAKSTKEKRLVAIKKMPHVTKRQQ 477
Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711
+ A+++++ H ++ +H + +V E++E G + +
Sbjct 478 QQNFREAAILAKCDHPNIVKLHTCHIDKDSNLWIVMEFMEGGTFEE--AAKAWKFNENNL 535
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE- 770
VA++L L YL ++VH ++ NI+++ G +KL D G+ +
Sbjct 536 AYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEG-------KVKLIDFGLCEDVATSTP 588
Query 771 -ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
V W+APE + + ST +D W F +LLE+ + P+ +
Sbjct 589 MHMVGSPFWMAPEMIQQKYH--STPVDIWSFAISLLEMA-NQRPPMMESAVKAMFTVATD 645
Query 830 QHRL---PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
P S CL +P +R + +L+
Sbjct 646 GATGFDDPALWSDCFKDFLSLCLKQDPAERATAEELLKHPF 686
>sp|Q39192|SRK2D_ARATH Serine/threonine-protein kinase SRK2D OS=Arabidopsis
thaliana OX=3702 GN=SRK2D PE=1 SV=1
Length=362
Score = 212 bits (540), Expect = 1e-59, Method: Composition-based stats.
Identities = 77/295 (26%), Positives = 124/295 (42%), Gaps = 26/295 (9%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
D T +P P P + ++D+G G+FG L T+ T E+VAVK +
Sbjct 1 MDPATNSPIMPIDLPIMHDSDRYDFVKDIGSGNFGVARLM----TDRVTKELVAVKYI-- 54
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-H 993
+ G + ++EI R+L H +I+++K L +VMEY G L + +
Sbjct 55 ERGEKIDENVQREIINHRSLRHPNIVRFKEVILTPSH--LAIVMEYAAGGELYERICNAG 112
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEG 1051
+ F QQ+ G++Y HA HRDL N LLD +KI DFG +K
Sbjct 113 RFSEDEARFFFQQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSK---SS 169
Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
+ + + +P + APE L ++ +DVWS GVTLY +L + P
Sbjct 170 VLHSQPKSTVGTPA-YIAPEILLRQEYDGKLADVWSCGVTLYVMLVGAYPFEDPQ----- 223
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + + +L +P E HL+ + + + R T +
Sbjct 224 -----EPRDYRKTIQRILSVTYSIPEDLHLSPECRHLISRIFVADPATRITIPEI 273
Score = 157 bits (398), Expect = 1e-40, Method: Composition-based stats.
Identities = 55/329 (17%), Positives = 95/329 (29%), Gaps = 41/329 (12%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
D + +G G DR + V +K +
Sbjct 19 DSDRYDFVKDIGSGNFG------------------------VARLMTDRVTKELVAVKYI 54
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ I + H ++ V + +V EY G L + G
Sbjct 55 ERG-EKIDENVQREIINHRSLRHPNIVRFKEVILTPSHLAIVMEYAAGGELYERI-CNAG 112
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
QQL S +SY + H ++ N LL +P +K+ D G
Sbjct 113 RFSEDEARFFFQQLISGVSYCHAMQICHRDLKLENTLLD-----GSPAPRLKICDFGYSK 167
Query 765 GAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
++ + V ++APE L D W G TL + + P
Sbjct 168 SSVLHSQPKSTVGTPAYIAPEILLRQEYD-GKLADVWSCGVTLYVMLVGAYPFEDPQEPR 226
Query 822 EKEHFYQRQ----HRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ QR + +PE P+ L S+ +P R + I D L+
Sbjct 227 DYRKTIQRILSVTYSIPEDLHLSPECRHLISRIFVADPATRITIPEITSDKWFLKNLPGD 286
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
+ S +P + ++ +
Sbjct 287 LMDENRMGSQFQEPEQPMQSLDTIMQIIS 315
>sp|Q1ZXD6|ROCO5_DICDI Probable serine/threonine-protein kinase
roco5 OS=Dictyostelium discoideum OX=44689 GN=roco5 PE=3 SV=1
Length=2800
Score = 229 bits (584), Expect = 1e-59, Method: Composition-based stats.
Identities = 75/284 (26%), Positives = 123/284 (43%), Gaps = 39/284 (14%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-----SGWKQEIDILRTLYH 956
+GEG FG V G++VA+K + D G +++E+ + TL H
Sbjct 2180 KVGEGGFGIVYKGKLR------GQLVAIKQITIDSGQAEAASEIYREFRREVWLSNTLTH 2233
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYL 1014
I+ KG C D +VMEY+P G+L +L + SI L A I + + ++
Sbjct 2234 PSIVSLKGYCLD----PCCIVMEYIPNGTLYSHLRKSFSSITWQLKLKIAINIADAIKHM 2289
Query 1015 H--AQHYIHRDLAARNVLLDNDRL----VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
H HRDL + N+L+ +D K+ DFG +AV + D S W
Sbjct 2290 HGFTPKICHRDLKSPNILMLSDMNAAVVCKVSDFGETRAVVTSA----LGRDKLSNPIWL 2345
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
+PE ++ ++ +DV+SFG+ L+E+LT P + +L + +
Sbjct 2346 SPEIMRGDEYTEKADVYSFGIVLWEILTGLLPFDEYPVAHSSF---------MYQLEDEI 2396
Query 1129 ERGERLPRPDKCP---CEVYHLMKNCWETEASFRPTFENLIPIL 1169
G R P + L+ +CW+ + RPTF ++ L
Sbjct 2397 TNGLRPTIPQNSVCGHPDFITLITDCWQNDPLKRPTFIDIHSRL 2440
Score = 200 bits (509), Expect = 1e-50, Method: Composition-based stats.
Identities = 64/338 (19%), Positives = 120/338 (36%), Gaps = 56/338 (17%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
+ T I+R P + ++ K++ + +G+G VY+G+LR +
Sbjct 2140 RSSITGEETIVRLDSLVPELMMSDIGPNFTLEYKDLEIIEKVGEGGFGIVYKGKLRGQ-- 2197
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA------LAFYETASLMSQVSH 667
V +K + F L + ++H
Sbjct 2198 ------------------------LVAIKQITIDSGQAEAASEIYREFRREVWLSNTLTH 2233
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE- 726
+ + G C+ +V EY+ +G L LR+ + K+ +A +A A+ ++
Sbjct 2234 PSIVSLKGYCLD--PCCIVMEYIPNGTLYSHLRKSFSSITWQLKLKIAINIADAIKHMHG 2291
Query 727 -NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPE 782
+ H ++ NIL + + K+SD G ++ +++ WL+PE
Sbjct 2292 FTPKICHRDLKSPNIL---MLSDMNAAVVCKVSDFGETRAVVTSALGRDKLSNPIWLSPE 2348
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS--------RSPSEKEHFYQRQHRLP 834
+ G + + D + FG L EI G P E E + +P
Sbjct 2349 IMRG--DEYTEKADVYSFGIVLWEIL-TGLLPFDEYPVAHSSFMYQLEDEITNGLRPTIP 2405
Query 835 E---PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
+ P TL + C +P +RP+F I L +
Sbjct 2406 QNSVCGHPDFITLITDCWQNDPLKRPTFIDIHSRLLIM 2443
>sp|Q9Z265|CHK2_MOUSE Serine/threonine-protein kinase Chk2 OS=Mus
musculus OX=10090 GN=Chek2 PE=1 SV=1
Length=546
Score = 218 bits (555), Expect = 1e-59, Method: Composition-based stats.
Identities = 98/436 (22%), Positives = 152/436 (35%), Gaps = 58/436 (13%)
Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFG-ATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832
PW L G ++L D + FG E CFDG ++ + R R
Sbjct 93 GPAPWARLWALQDGFSNLDCVNDNYWFGRDKSCEYCFDGPLLRRTDKYRTYSKKHFRIFR 152
Query 833 -LPEPSCPQLA--------TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
+ +C + T + L + + P L+ + D
Sbjct 153 EMGPKNCYIVYIEDHSGNGTFVNTELIGKGKRCPLSNNSEIALSLCRNKVFVFFDLTVDD 212
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
+ + LG G G+V + T + VA+K + S
Sbjct 213 QSVYP--KELRDEYIMSKTLGSGACGEVKMAF----ERKTCQKVAIKIISKRRFALGSSR 266
Query 944 -------WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSI 995
+ EI+IL+ L H IIK K + +V+E + G L D + +
Sbjct 267 EADTAPSVETEIEILKKLNHPCIIKIKDVF---DAEDYYIVLELMEGGELFDRVVGNKRL 323
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGH 1052
A L+ Q+ + YLH IHRDL NVLL D L+KI DFG +K + E
Sbjct 324 KEATCKLYFYQMLVAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGE-- 381
Query 1053 EYYRVREDGDSPVFWYAPECLKEY---KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109
+R +P + APE L + A D WS GV L+ L+
Sbjct 382 -TSLMRTLCGTPT-YLAPEVLVSNGTAGYSRAVDCWSLGVILFICLSGYPPFSE------ 433
Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPD---KCPCEVYHLMKNCWETEASFRPTFENLI 1166
T + L + + G+ P+ E L+K + R T E +
Sbjct 434 --------HKTQVSLKDQITSGKYNFIPEVWTDVSEEALDLVKKLLVVDPKARLTTEEAL 485
Query 1167 --PIL--KTVHEKYQG 1178
P L + + +K+Q
Sbjct 486 NHPWLQDEYMKKKFQD 501
Score = 153 bits (386), Expect = 1e-37, Method: Composition-based stats.
Identities = 64/393 (16%), Positives = 117/393 (30%), Gaps = 59/393 (15%)
Query 494 PDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLP 553
D ++ + F I F G + G + + C
Sbjct 137 TDKYRTYSKKHFRI------FREMGPKNCYIV---YIEDHSGNGTFVNTELIGKGKRCPL 187
Query 554 QPGETSNLIIMRGARASPRTLNLSQLS-FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
L + R L + S + + + E LG G V
Sbjct 188 SNNSEIALSLCRNKVFVFFDLTVDDQSVYPKELRDEYIMSKTLGSGACGEV--------- 238
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--------HHDIALAFYETASLMSQ 664
+R +V +K++ D A + ++ +
Sbjct 239 ---------------KMAFERKTCQKVAIKIISKRRFALGSSREADTAPSVETEIEILKK 283
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
++H + + V + +V E +E G L + + + A + Q+ A+ Y
Sbjct 284 LNHPCIIKIKDV-FDAEDYYIVLELMEGGELFDRVVGNK-RLKEATCKLYFYQMLVAVQY 341
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAP 781
L ++H ++ N+LL+ + IK++D G +LAP
Sbjct 342 LHENGIIHRDLKPENVLLSS----QEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAP 397
Query 782 ECL-PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS---EKEHFYQRQHRLPEPS 837
E L G S A+D W G L IC G P + + + + +PE
Sbjct 398 EVLVSNGTAGYSRAVDCWSLGVIL-FICLSGYPPFSEHKTQVSLKDQITSGKYNFIPEVW 456
Query 838 ---CPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ L + L +P R + L
Sbjct 457 TDVSEEALDLVKKLLVVDPKARLTTEEALNHPW 489
>sp|Q2H332|HOG1_CHAGB Mitogen-activated protein kinase HOG1 OS=Chaetomium
globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962
/ NBRC 6347 / NRRL 1970) OX=306901 GN=HOG1 PE=3 SV=1
Length=360
Score = 212 bits (540), Expect = 1e-59, Method: Composition-based stats.
Identities = 65/283 (23%), Positives = 107/283 (38%), Gaps = 29/283 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VA+K + K P +E+ +L+ L HE++
Sbjct 24 QPVGMGAFGLVC----SAKDQLTSQNVAIKKIMKPFSTPVLAKRTYRELKLLKHLKHENV 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L ER P + L++ + R T +
Sbjct 252 SLPMRERQPLKNKFKNADPTAIDLLERMLVFDPKKRITATEAL 294
Score = 128 bits (322), Expect = 9e-31, Method: Composition-based stats.
Identities = 36/231 (16%), Positives = 75/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E D + M + +D+ V +K ++ P +A Y
Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSAKDQLTSQNVAIKKIMKPFSTPVLAKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLKHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q9VI13|PAK_DROME Serine/threonine-protein kinase Pak OS=Drosophila
melanogaster OX=7227 GN=Pak PE=1 SV=1
Length=704
Score = 222 bits (565), Expect = 1e-59, Method: Composition-based stats.
Identities = 68/275 (25%), Positives = 112/275 (41%), Gaps = 23/275 (8%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
R K+ +G+G G V Y TG VA+K + P+ + EI ++R
Sbjct 426 PNRKYTKMEKIGQGASGTV----YTAIESSTGMEVAIKQMNLSQQPK-KELIINEILVMR 480
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
H +++ Y E L +VMEY+P GSL D + + Q+ +++ + +
Sbjct 481 ENKHPNVVNYLDSYLVSEE--LWVVMEYLPGGSLTDVVTETCMDEGQIAAVCREVLQALE 538
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+LHA IHRD+ + N+LL D VK+ DFG + R +W APE
Sbjct 539 FLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISP---EQSKRTTMVGTPYWMAPEV 595
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ ++ D+WS G+ E++ PP + T + E+ E+
Sbjct 596 VTRKQYGPKVDLWSLGIMAIEMV-----EGEPPYLNENPLKALYLIATNGK-PEIKEK-- 647
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
DK + C E E R + +L+
Sbjct 648 -----DKLSSAFQDFLDQCLEVEVDRRASALDLLK 677
Score = 183 bits (464), Expect = 1e-46, Method: Composition-based stats.
Identities = 49/276 (18%), Positives = 90/276 (33%), Gaps = 44/276 (16%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
++ T++ +GQG VY + + V +K +
Sbjct 426 PNRKYTKMEKIGQGASGTVY------------------------TAIESSTGMEVAIKQM 461
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ S +M + H ++ + E +V EY+ G L +
Sbjct 462 NLSQQPKKELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVV--TET 519
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV-- 762
+ V +++ AL +L ++H ++ NILL G +KL+D G
Sbjct 520 CMDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILL-------GLDGSVKLTDFGFCA 572
Query 763 --GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
R V W+APE + +D W G +E+ +GE P + +P
Sbjct 573 QISPEQSKRTTMVGTPYWMAPEVVT--RKQYGPKVDLWSLGIMAIEMV-EGEPPYLNENP 629
Query 821 SEKEHFYQRQHRLP----EPSCPQLATLTSQCLTYE 852
+ + + + QCL E
Sbjct 630 LKALYLIATNGKPEIKEKDKLSSAFQDFLDQCLEVE 665
>sp|Q9STF0|LRKS3_ARATH Receptor like protein kinase S.3 OS=Arabidopsis
thaliana OX=3702 GN=LECRKS3 PE=3 SV=1
Length=337
Score = 211 bits (538), Expect = 1e-59, Method: Composition-based stats.
Identities = 66/266 (25%), Positives = 106/266 (40%), Gaps = 20/266 (8%)
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968
G V + +AVK + D Q +I + L H+++++ G C
Sbjct 62 GTVYKG-----KLSSNAQIAVKRVSLDA-EQDTKHLVSQIVGIGKLRHKNLVQLLGYCRR 115
Query 969 QGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
+GE L LV +Y+P G+L D+L R ++ +Q + + + YLH Q +HRD+
Sbjct 116 KGE--LLLVYDYMPYGNLDDFLFNEERPNLSWSQRFHIIKGVASALLYLHEQIVLHRDVK 173
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
A NVLLD D ++ D+GLA+ + R V + APE + +DV+
Sbjct 174 AANVLLDEDLNGRL-DYGLAR-------FGTNRNPMLGSVGYVAPELIITGMPTTKADVY 225
Query 1086 SFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144
SFG L E + P + LI L + K V
Sbjct 226 SFGALLLEFACGRMFIEYPGKPEEFNLISWVCQCWKRGNLVGARDARLEGDYVCKEIEMV 285
Query 1145 YHLMKNCWETEASFRPTFENLIPILK 1170
L C + RP+ ++ L+
Sbjct 286 LKLGLLCAQYNPEDRPSMSQVVNYLE 311
Score = 196 bits (498), Expect = 3e-54, Method: Composition-based stats.
Identities = 59/299 (20%), Positives = 101/299 (34%), Gaps = 53/299 (18%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
K + G VY+G+L ++ +K +
Sbjct 46 ATKGFKESELFGTEANGTVYKGKLSSNA-------------------------QIAVKRV 80
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ER 703
+ ++ H +L + G C R E ++V +Y+ +G LD +L ER
Sbjct 81 SLDAEQDTKHLVSQIVGIGKLRHKNLVQLLGYCRRKGELLLVYDYMPYGNLDDFLFNEER 140
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
++ + + + + +ASAL YL + ++H +V N+LL D G+
Sbjct 141 PNLSWSQRFHIIKGVASALLYLHEQIVLHRDVKAANVLLDEDLNGRL--------DYGLA 192
Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+R + + ++APE + G +T D + FGA LLE P E
Sbjct 193 RFGTNRNPMLGSVGYVAPELIITGMP--TTKADVYSFGALLLEFACGRMFIEYPGKPEEF 250
Query 824 EHFYQ-------------RQHRLP----EPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
R RL + L C Y P RPS ++
Sbjct 251 NLISWVCQCWKRGNLVGARDARLEGDYVCKEIEMVLKLGLLCAQYNPEDRPSMSQVVNY 309
>sp|P28829|BYR2_SCHPO Protein kinase byr2 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=byr2 PE=1 SV=1
Length=659
Score = 221 bits (562), Expect = 1e-59, Method: Composition-based stats.
Identities = 70/282 (25%), Positives = 118/282 (42%), Gaps = 32/282 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-------WKQEID 949
+ +G G FG+V L N +GE++AVK + D + + EI
Sbjct 394 WIRGALIGSGSFGQVYLGM----NASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIA 449
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQIC 1008
+L+ L HEHI++Y G + L + +EYVP GS+ L + L+ F +Q
Sbjct 450 LLQELSHEHIVQYLGS--NLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTL 507
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV---REDGDSPV 1065
+G+ YLH++ +HRD+ N+L+DN +KI DFG++K + + R
Sbjct 508 KGLEYLHSRGIVHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQGSS 567
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
FW APE +K+ +D+WS G + E+LT ++
Sbjct 568 FWMAPEVVKQTMHTEKTDIWSLGCLVIEMLTSKHP---------------YPNCDQMQAI 612
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ P ++ + + + RPT L+
Sbjct 613 FRIGENILPEFPSNISSSAIDFLEKTFAIDCNLRPTASELLS 654
Score = 171 bits (434), Expect = 4e-43, Method: Composition-based stats.
Identities = 57/290 (20%), Positives = 98/290 (34%), Gaps = 42/290 (14%)
Query 563 IMRGARASPRTLNLSQLSFHRVDQKE--ITQLS--HLGQGTRTNVYEGRLRVEGSGDPEE 618
I + + SP + + D + I + +G G+ VY G G +
Sbjct 364 IEQPSPISPTSTTSEDTNTLEEDTDDQSIKWIRGALIGSGSFGQVYLGMNASSGELMAVK 423
Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678
+ D R K+LD A +L+ ++SH H+ G +
Sbjct 424 QVILDSVSESKDRHA--------KLLD--------ALAGEIALLQELSHEHIVQYLGSNL 467
Query 679 RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGR 738
+ EYV G + L G +Q L YL ++ +VH ++ G
Sbjct 468 NSDHLNIFLEYVPGGSVAGLL-TMYGSFEETLVKNFIKQTLKGLEYLHSRGIVHRDIKGA 526
Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER----------IPWLAPECLPGGA 788
NIL+ G IK+SD G+ + W+APE +
Sbjct 527 NILVDNKG-------KIKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPEVVKQTM 579
Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838
+ + D W G ++E+ + P + + F ++ LPE
Sbjct 580 H--TEKTDIWSLGCLVIEMLTS-KHPYPNCDQMQAI-FRIGENILPEFPS 625
>sp|Q8RWZ5|SD25_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase SD2-5 OS=Arabidopsis thaliana OX=3702
GN=SD25 PE=1 SV=1
Length=821
Score = 224 bits (570), Expect = 1e-59, Method: Composition-based stats.
Identities = 71/314 (23%), Positives = 126/314 (40%), Gaps = 25/314 (8%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942
LG+G FG V G +AVK L + Q +
Sbjct 479 MPIRFAYKDLQSATNNFSVKLGQGGFGSVYEGTL-----PDGSRLAVKKL--EGIGQGKK 531
Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGL 997
++ E+ I+ +++H H+++ +G C + + L E++ GSL ++ R +
Sbjct 532 EFRAEVSIIGSIHHLHLVRLRGFCAEGAHR--LLAYEFLSKGSLERWIFRKKDGDVLLDW 589
Query 998 AQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
A +G+AYLH +H D+ N+LLD++ K+ DFGLAK + +
Sbjct 590 DTRFNIALGTAKGLAYLHEDCDARIVHCDIKPENILLDDNFNAKVSDFGLAKLMTREQSH 649
Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL-ELIG 1113
V + APE + Y SDV+S+G+ L EL+ + T
Sbjct 650 --VFTTMRGTRGYLAPEWITNYAISEKSDVYSYGMVLLELIGGRKNYDPSETSEKCHFPS 707
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170
A +M +L ++++ ++ D V MK C + + RP+ ++ +L+
Sbjct 708 FAFKKMEEGKLMDIVD--GKMKNVDVTDERVQRAMKTALWCIQEDMQTRPSMSKVVQMLE 765
Query 1171 TVHEKYQGQAPSVF 1184
V Q + S
Sbjct 766 GVFPVVQPPSSSTM 779
Score = 196 bits (498), Expect = 2e-50, Method: Composition-based stats.
Identities = 57/250 (23%), Positives = 91/250 (36%), Gaps = 47/250 (19%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LGQG +VYEG L R+ +K L
Sbjct 498 KLGQGGFGSVYEGTLPDGS-------------------------RLAVKKL-EGIGQGKK 531
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH---VPMAW 710
F S++ + H HL + G C G ++ E++ G L+ W+ R++ +
Sbjct 532 EFRAEVSIIGSIHHLHLVRLRGFCAEGAHRLLAYEFLSKGSLERWIFRKKDGDVLLDWDT 591
Query 711 KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
+ +A A L+YL +VH ++ NILL + K+SD G+
Sbjct 592 RFNIALGTAKGLAYLHEDCDARIVHCDIKPENILLD-------DNFNAKVSDFGLAKLMT 644
Query 768 SREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ V +LAPE + ++S D + +G LLE+ G SE
Sbjct 645 REQSHVFTTMRGTRGYLAPEWITN--YAISEKSDVYSYGMVLLELI-GGRKNYDPSETSE 701
Query 823 KEHFYQRQHR 832
K HF +
Sbjct 702 KCHFPSFAFK 711
>sp|C0LGD6|Y1570_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g05700 OS=Arabidopsis thaliana OX=3702
GN=At1g05700 PE=1 SV=1
Length=852
Score = 224 bits (571), Expect = 2e-59, Method: Composition-based stats.
Identities = 65/328 (20%), Positives = 128/328 (39%), Gaps = 17/328 (5%)
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919
R R + + + + K + LG+G FG V YD
Sbjct 533 RIRNRRNKSVNSAPQTSPMAKSENKLLFTFADVIKMTNNFGQVLGKGGFGTVYHGFYD-- 590
Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979
VAVK L ++ Q ++ E+++L ++H ++ G + + + L+ E
Sbjct 591 ----NLQVAVK-LLSETSAQGFKEFRSEVEVLVRVHHVNLTALIGYFHEGDQ--MGLIYE 643
Query 980 YVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDN 1033
++ G++ D+L +H++ Q L A +G+ YLH +HRD+ N+LL+
Sbjct 644 FMANGNMADHLAGKYQHTLSWRQRLQIALDAAQGLEYLHCGCKPPIVHRDVKTSNILLNE 703
Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
K+ DFGL+++ + +P + P C + SD++SFGV L E
Sbjct 704 KNRAKLADFGLSRSFHTESRSHVSTLVAGTP-GYLDPLCFETNGLNEKSDIYSFGVVLLE 762
Query 1094 LLTHCDSSQSPPTKFLELIGIA-QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152
++T + TK + + + + +++ +V L +
Sbjct 763 MITGKTVIKESQTKRVHVSDWVISILRSTNDVNNVIDSKMAKDFDVNSVWKVVELALSSV 822
Query 1153 ETEASFRPTFENLIPILKTVHEKYQGQA 1180
S RP +++ L ++ +
Sbjct 823 SQNVSDRPNMPHIVRGLNECLQREESNK 850
Score = 194 bits (492), Expect = 2e-49, Method: Composition-based stats.
Identities = 54/268 (20%), Positives = 92/268 (34%), Gaps = 47/268 (18%)
Query 554 QPGETSNLIIMRGARASP--RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
+ N + + SP ++ N +F V + LG+G VY G
Sbjct 533 RIRNRRNKSVNSAPQTSPMAKSENKLLFTFADVIKMTNNFGQVLGKGGFGTVYHG----- 587
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
L+V +K+L + F ++ +V H +L
Sbjct 588 ---------------------FYDNLQVAVKLLSETSAQGFKEFRSEVEVLVRVHHVNLT 626
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLE---N 727
+ G G + ++ E++ +G + L + H + ++ +A A L YL
Sbjct 627 ALIGYFHEGDQMGLIYEFMANGNMADHLAGKYQHTLSWRQRLQIALDAAQGLEYLHCGCK 686
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAP 781
+VH +V NILL A KL+D G+ + +L P
Sbjct 687 PPIVHRDVKTSNILLNEKNRA-------KLADFGLSRSFHTESRSHVSTLVAGTPGYLDP 739
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICF 809
L N L+ D + FG LLE+
Sbjct 740 --LCFETNGLNEKSDIYSFGVVLLEMIT 765
>sp|U4PR86|MELK_CAEEL Maternal embryonic leucine zipper kinase
OS=Caenorhabditis elegans OX=6239 GN=pig-1 PE=1 SV=1
Length=706
Score = 221 bits (564), Expect = 2e-59, Method: Composition-based stats.
Identities = 65/283 (23%), Positives = 114/283 (40%), Gaps = 24/283 (8%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
+ + +LG G FGKV L T+ T + VA+K + +
Sbjct 1 MSKYEVLQGFYAVHDELGSGGFGKVRL----ATHLLTNQKVAIKIIDKKQLGHDLPRVQT 56
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQ 1005
E+D LR L H++I + E E +VMEY G + DY+ + + ++ F +
Sbjct 57 EMDALRNLSHQNICRLYHYIE--TEDKFFIVMEYCSGGEMFDYIVRKERLEESEARHFFR 114
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
Q+ +A++H+Q Y HRDL N+LL D +K+ DFGL +G +
Sbjct 115 QLVSAIAFVHSQGYAHRDLKPENLLLTEDLHLKLIDFGLCAKTEKGRIDKHNLDTCCGSP 174
Query 1066 FWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+ APE ++ ++ +DVWS G+ LY LL + +++
Sbjct 175 AYAAPELIQGLQYKGNEADVWSMGILLYTLLVGALPFED----------------DNMQI 218
Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ P+ L++ + R + + L+
Sbjct 219 MYKKIQSGCFYEPEFLSPLSKQLLRAMLQVVPERRISVKKLLE 261
Score = 157 bits (397), Expect = 3e-38, Method: Composition-based stats.
Identities = 48/320 (15%), Positives = 91/320 (28%), Gaps = 43/320 (13%)
Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH--H 649
LG G V +V +K++D H
Sbjct 14 HDELGSGGFGKV------------------------RLATHLLTNQKVAIKIIDKKQLGH 49
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
D+ + +SH ++ ++ + +V EY G + ++ R+ + +
Sbjct 50 DLPR-VQTEMDALRNLSHQNICRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKE-RLEES 107
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG------ 763
+QL SA++++ ++ H ++ N+LL +KL D G+
Sbjct 108 EARHFFRQLVSAIAFVHSQGYAHRDLKPENLLLTE-------DLHLKLIDFGLCAKTEKG 160
Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ + + + APE + G D W G L +
Sbjct 161 RIDKHNLDTCCGSPAYAAPELIQGLQYK-GNEADVWSMGILLYTLLVGALPFEDDNMQIM 219
Query 823 KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
+ PE P L L P +R S + +L +
Sbjct 220 YKKIQSGCFYEPEFLSPLSKQLLRAMLQVVPERRISVKKLLEHDWLNHKYTQPVKWNTIY 279
Query 883 DSPASDPTVFHKRYLKKIRD 902
D D V +
Sbjct 280 DKNFIDRDVARVMSKYYGFE 299
>sp|Q75H77|SAPKA_ORYSJ Serine/threonine-protein kinase SAPK10
OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK10 PE=1 SV=1
Length=362
Score = 212 bits (540), Expect = 2e-59, Method: Composition-based stats.
Identities = 73/286 (26%), Positives = 120/286 (42%), Gaps = 30/286 (10%)
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945
P + + +RD+G G+FG L + G++VAVK + + G + +
Sbjct 12 MDMPIMHDGDRYELVRDIGSGNFGVARLM----RSRADGQLVAVKYI--ERGDKIDENVQ 65
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFA 1004
+EI R+L H +II++K L +VMEY G L + + + F
Sbjct 66 REIINHRSLRHPNIIRFKEVILTPTH--LAIVMEYASGGELFERICNAGRFSEDEARFFF 123
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGD 1062
QQ+ G++Y H+ HRDL N LLD +KI DFG +K + + +
Sbjct 124 QQLISGVSYCHSMQVCHRDLKLENTLLDGSTAPRLKICDFGYSK---SSVLHSQPKSTVG 180
Query 1063 SPVFWYAPECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
+P + APE L + ++ +DVWS GVTLY +L + P + T+
Sbjct 181 TPA-YIAPEVLLKKEYDGKIADVWSCGVTLYVMLVGAYPFEDPDEP-------KNFRKTI 232
Query 1122 LRLTELLERGERLPRPD--KCPCEVYHLMKNCWETEASFRPTFENL 1165
R+ G + PD E L+ + + R + +
Sbjct 233 QRIL-----GVQYSIPDYVHISPECRDLIARIFVANPATRISIPEI 273
Score = 158 bits (400), Expect = 5e-41, Method: Composition-based stats.
Identities = 54/329 (16%), Positives = 93/329 (28%), Gaps = 41/329 (12%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
D + +G G R R V +K +
Sbjct 19 DGDRYELVRDIGSGNFG------------------------VARLMRSRADGQLVAVKYI 54
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ I + H ++ V + +V EY G L + G
Sbjct 55 ERGDK-IDENVQREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERI-CNAG 112
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
QQL S +SY + + H ++ N LL T+P +K+ D G
Sbjct 113 RFSEDEARFFFQQLISGVSYCHSMQVCHRDLKLENTLLD-----GSTAPRLKICDFGYSK 167
Query 765 GAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
++ + V ++APE L D W G TL + P
Sbjct 168 SSVLHSQPKSTVGTPAYIAPEVLLKKEYD-GKIADVWSCGVTLYVMLVGAYPFEDPDEPK 226
Query 822 E----KEHFYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ Q+ +P+ P+ L ++ P R S I L+
Sbjct 227 NFRKTIQRILGVQYSIPDYVHISPECRDLIARIFVANPATRISIPEIRNHPWFLKNLPAD 286
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
+ S +P + + ++ L
Sbjct 287 LMDDSKMSSQYEEPEQPMQSMDEIMQILA 315
>sp|O70146|TESK1_MOUSE Dual specificity testis-specific protein
kinase 1 OS=Mus musculus OX=10090 GN=Tesk1 PE=1 SV=3
Length=627
Score = 220 bits (560), Expect = 2e-59, Method: Composition-based stats.
Identities = 73/290 (25%), Positives = 123/290 (42%), Gaps = 28/290 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+G G F +V Y + +G+++ LK + P +RS +E+ ++ L H
Sbjct 52 FDCAEKIGAGFFSEV----YKVRHRQSGQVM---VLKMNKLPSNRSNTLREVQLMNRLRH 104
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLH 1015
+I+++ G C QG+ L + EY+ G+L L + L A I +G+ YLH
Sbjct 105 PNILRFMGVCVHQGQ--LHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIAQGLRYLH 162
Query 1016 AQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVRE-DGDSPVFWYAPE 1071
A+ HRDL ++N L+ D +GDFGLA+ +P E R +W APE
Sbjct 163 AKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGTRKEPLAVVGSPYWMAPE 222
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
L+ + +DV++FG+ L EL+ + + + T++
Sbjct 223 VLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVG-------- 274
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181
+ CP L +C E S R F + L+ + E+ P
Sbjct 275 ------NDCPLPFLLLAIHCCSMEPSTRAPFTEITQHLEQILEQQPEATP 318
Score = 192 bits (489), Expect = 2e-50, Method: Composition-based stats.
Identities = 69/316 (22%), Positives = 113/316 (36%), Gaps = 45/316 (14%)
Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628
+S R L + S RVD + +G G + VY+ R R G
Sbjct 34 SSYRALRSAVSSLARVD--DFDCAEKIGAGFFSEVYKVRHRQSG---------------- 75
Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+V++ ++ + + LM+++ H ++ GVCV + +TE
Sbjct 76 ---------QVMVLKMNKLPSNRSNT-LREVQLMNRLRHPNILRFMGVCVHQGQLHALTE 125
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
Y+ G L+ L + ++ +A +A L YL K + H ++ +N L+ R
Sbjct 126 YMNGGTLEQLLSSPE-PLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRR---- 180
Query 749 EGTSPFIKLSDPGVG-LGALSREER-------VERIPWLAPECLPGGANSLSTAMDKWGF 800
E + D G+ + RE V W+APE L G D + F
Sbjct 181 EDRGFTAVVGDFGLAEKIPVYREGTRKEPLAVVGSPYWMAPEVLRGEL--YDEKADVFAF 238
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-LPEPSCP-QLATLTSQCLTYEPTQRPS 858
G L E+ A +E R L CP L C + EP+ R
Sbjct 239 GIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSTRAP 298
Query 859 FRTILRDLTRLQPHNL 874
F I + L ++
Sbjct 299 FTEITQHLEQILEQQP 314
>sp|Q8CFH6|SIK2_MOUSE Serine/threonine-protein kinase SIK2 OS=Mus
musculus OX=10090 GN=Sik2 PE=1 SV=1
Length=931
Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats.
Identities = 71/291 (24%), Positives = 112/291 (38%), Gaps = 29/291 (10%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADC 936
+ + + LG+G+F V L + T VA+K + K+
Sbjct 1 MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLG----RHRTTKTEVAIKIIDKSQL 56
Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SI 995
+ +E+ I++ L H HIIK E + L LV EY G + DYL H +
Sbjct 57 DAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKS--MLYLVTEYAKNGEIFDYLANHGRL 114
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
++ QI + Y H + +HRDL A N+LLDN+ +KI DFG G
Sbjct 115 NESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLLDNNMNIKIADFGFGNFFKTGE--- 171
Query 1056 RVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ + APE + ++ D+WS GV LY L+ P
Sbjct 172 -LLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGP---------- 220
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
T+ L + + G R P + HL++ + S R + +
Sbjct 221 -----TLPILRQRVLEG-RFRIPYFMSEDCEHLIRRMLVLDPSKRLSIAQI 265
Score = 195 bits (496), Expect = 8e-50, Method: Composition-based stats.
Identities = 74/383 (19%), Positives = 125/383 (33%), Gaps = 48/383 (13%)
Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
PR L + RV +I LG+G V GR R
Sbjct 7 PRHLQRGPV---RVGFYDIE--GTLGKGNFAVVKLGRHRT-------------------- 41
Query 631 RDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+ V +K++D S D Y +M + H H+ ++ V +VTE
Sbjct 42 ----TKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTE 97
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
Y ++G + +L G + + Q+ SA+ Y + +VH ++ N+LL
Sbjct 98 YAKNGEIFDYLANH-GRLNESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLLDN---- 152
Query 749 EGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ IK++D G G + E P+ APE G +D W G L
Sbjct 153 ---NMNIKIADFGFGNFFKTGELLATWCGSPPYAAPEVFEGQQYE-GPQLDIWSMGVVLY 208
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ P ++ + + R+P L + L +P++R S I
Sbjct 209 VLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLSIAQIKEH 268
Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYL-KKIRDLGEGHFGKVSLYCYDPTNDGTG 924
L + + + + + + LG V N
Sbjct 269 KWMLIEVPVQRPILYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKTVE----SLQNKSYN 324
Query 925 EMVAVKALKADCGPQHRSGWKQE 947
A+ L + HRS + E
Sbjct 325 HFAAIYFLLVERLKSHRSSFPVE 347
>sp|C0LGJ1|Y1743_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At1g74360 OS=Arabidopsis thaliana OX=3702
GN=At1g74360 PE=1 SV=1
Length=1106
Score = 227 bits (578), Expect = 2e-59, Method: Composition-based stats.
Identities = 64/284 (23%), Positives = 118/284 (42%), Gaps = 19/284 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY-----HE 957
+G G +G V G VAVK L+ + + ++ E+++L H
Sbjct 820 VGRGGYGTVYRGVL-----PDGREVAVKKLQREGTEAEKE-FRAEMEVLSANAFGDWAHP 873
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHA 1016
++++ G C D EK LV EY+ GSL + + + + + + A + G+ +LH
Sbjct 874 NLVRLYGWCLDGSEK--ILVHEYMGGGSLEELITDKTKLQWKKRIDIATDVARGLVFLHH 931
Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ +HRD+ A NVLLD ++ DFGLA+ + G + V + + APE
Sbjct 932 ECYPSIVHRDVKASNVLLDKHGNARVTDFGLARLLNVGDSH--VSTVIAGTIGYVAPEYG 989
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ ++ DV+S+GV EL T + +E + + + G +
Sbjct 990 QTWQATTRGDVYSYGVLTMELATGRRAVDGGEECLVEWARRVMTGNMTAKGSPITLSGTK 1049
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
+ E+ + C RP + ++ +L + K +
Sbjct 1050 PGNGAEQMTELLKIGVKCTADHPQARPNMKEVLAMLVKISGKAE 1093
Score = 187 bits (475), Expect = 5e-47, Method: Composition-based stats.
Identities = 47/242 (19%), Positives = 91/242 (38%), Gaps = 48/242 (20%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
++ +G+G VY G L V +K L
Sbjct 810 ATSNFSEERVVGRGGYGTVYRGVLPDGR-------------------------EVAVKKL 844
Query 645 DPSHHDIALAFYETASLMS-----QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+ F ++S +H +L ++G C+ G E I+V EY+ G L+ +
Sbjct 845 QREGTEAEKEFRAEMEVLSANAFGDWAHPNLVRLYGWCLDGSEKILVHEYMGGGSLEELI 904
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIK 756
++ + ++ +A +A L +L ++ ++VH +V N+LL + G +
Sbjct 905 -TDKTKLQWKKRIDIATDVARGLVFLHHECYPSIVHRDVKASNVLLDKHG-------NAR 956
Query 757 LSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
++D G+ + V I ++APE G +T D + +G +E+
Sbjct 957 VTDFGLARLLNVGDSHVSTVIAGTIGYVAPEY--GQTWQATTRGDVYSYGVLTMELATGR 1014
Query 812 EA 813
A
Sbjct 1015 RA 1016
>sp|Q86AD7|MYLKB_DICDI Probable myosin light chain kinase DDB_G0271550
OS=Dictyostelium discoideum OX=44689 GN=DDB_G0271550
PE=3 SV=1
Length=392
Score = 213 bits (542), Expect = 2e-59, Method: Composition-based stats.
Identities = 65/281 (23%), Positives = 105/281 (37%), Gaps = 32/281 (11%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRT 953
+ + ++G G F V T+ TG+ VA+KA+ K + +EI+I++
Sbjct 18 DFYEFGPEIGRGAFSIVR----QGTHKDTGDQVAIKAISKQHVSEADMKRFTREIEIMKK 73
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012
L H++II+ + L LV+E + G L D + + + +QI +
Sbjct 74 LKHKNIIQLIEVFDSND--YLYLVLELIRGGELFDKIVEKGNYSEKDACNLVRQIVSAVE 131
Query 1013 YLHAQHYIHRDLAARNVLLDNDRL----VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
Y+H HRDL N+L D V+I DFGL+K G E + +
Sbjct 132 YMHQHGVCHRDLKPENLLCSGDDEKEEIVRIADFGLSKIFEGGEEL----KTACGTPDYV 187
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
APE L+ + + D+WS GV Y LL + L ++L
Sbjct 188 APEILECKPYDTSVDMWSIGVITYILLCGFAPFYADTHHEL--------------FQKIL 233
Query 1129 ERGERLPRPD--KCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ P P+ + R T I
Sbjct 234 DLEYDFPEPEWNGITDLAKDFISQLLIINPEERWTASQCIK 274
Score = 167 bits (422), Expect = 1e-43, Method: Composition-based stats.
Identities = 53/304 (17%), Positives = 109/304 (36%), Gaps = 48/304 (16%)
Query 581 FHRVDQKEITQLS-------HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
F R+ +K+ +++ +G+G + V +G + G
Sbjct 5 FKRIGRKKDSKIEDFYEFGPEIGRGAFSIVRQGTHKDTGD-------------------- 44
Query 634 GQELRVVLKVLDPSHHDI--ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+V +K + H F +M ++ H ++ + V +V E +
Sbjct 45 ----QVAIKAISKQHVSEADMKRFTREIEIMKKLKHKNIIQLIEVFDSNDYLYLVLELIR 100
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G L + E+G+ + +Q+ SA+ Y+ + H ++ N+L + +
Sbjct 101 GGELFDKI-VEKGNYSEKDACNLVRQIVSAVEYMHQHGVCHRDLKPENLLCS---GDDEK 156
Query 752 SPFIKLSDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
++++D G+ G + ++APE L T++D W G I
Sbjct 157 EEIVRIADFGLSKIFEGGEELKTACGTPDYVAPEILE--CKPYDTSVDMWSIGVITY-IL 213
Query 809 FDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQLATL----TSQCLTYEPTQRPSFRTIL 863
G AP + + E + ++ PEP + L SQ L P +R + +
Sbjct 214 LCGFAPFYADTHHELFQKILDLEYDFPEPEWNGITDLAKDFISQLLIINPEERWTASQCI 273
Query 864 RDLT 867
+
Sbjct 274 KHPW 277
>sp|F1QGZ6|MELK_DANRE Maternal embryonic leucine zipper kinase
OS=Danio rerio OX=7955 GN=melk PE=2 SV=1
Length=676
Score = 221 bits (562), Expect = 2e-59, Method: Composition-based stats.
Identities = 74/274 (27%), Positives = 121/274 (44%), Gaps = 26/274 (9%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
+ + +G G F KV L + TGE VA+K ++ K EI+ ++ L
Sbjct 12 HYEVYETIGSGGFAKVKLG----RHKLTGEKVAIKIMEKKDLGDDLPRVKIEIEAMKNLS 67
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYL 1014
H+H+ + E + + +V+EY P G L DY+ + + + +F +QI +AY+
Sbjct 68 HQHVCRLYHVIETTSK--IYMVLEYCPGGELFDYIIAKDRLSEEETRVFFRQIISALAYV 125
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H+Q Y HRDL N+L+D D +K+ DFGL A P+G + + SP + APE ++
Sbjct 126 HSQGYAHRDLKPENLLIDEDHNLKLIDFGLC-AKPKGGLGFELLTCCGSPA-YAAPELIQ 183
Query 1075 EYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ +DVWS GV LY LL + L + RG +
Sbjct 184 GKAYIGSEADVWSMGVLLYALLCGFLPFDDD---------------NCMVLYRKITRG-K 227
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P L+ + + R T ++L+
Sbjct 228 YSNPHWLSPSSILLLNQMMQVDPKRRLTVKHLLD 261
Score = 172 bits (437), Expect = 2e-43, Method: Composition-based stats.
Identities = 54/315 (17%), Positives = 102/315 (32%), Gaps = 39/315 (12%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-D 645
K +G G V GR ++ G +V +K++
Sbjct 11 KHYEVYETIGSGGFAKVKLGRHKLTGE------------------------KVAIKIMEK 46
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
D M +SH H+ ++ V + MV EY G L ++ +
Sbjct 47 KDLGDDLPRVKIEIEAMKNLSHQHVCRLYHVIETTSKIYMVLEYCPGGELFDYIIA-KDR 105
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763
+ V +Q+ SAL+Y+ ++ H ++ N+L+ +KL D G+
Sbjct 106 LSEEETRVFFRQIISALAYVHSQGYAHRDLKPENLLIDE-------DHNLKLIDFGLCAK 158
Query 764 -LGALSRE--ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
G L E + APE + G A + + D W G L +
Sbjct 159 PKGGLGFELLTCCGSPAYAAPELIQGKAY-IGSEADVWSMGVLLYALLCGFLPFDDDNCM 217
Query 821 SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880
+ ++ P P L +Q + +P +R + + +L ++ ++
Sbjct 218 VLYRKITRGKYSNPHWLSPSSILLLNQMMQVDPKRRLTVKHLLDHPWVMRGYSTPVEWHS 277
Query 881 NPDSPASDPTVFHKR 895
D +
Sbjct 278 KYPLGHIDEDCITEM 292
>sp|O08911|MK12_MOUSE Mitogen-activated protein kinase 12 OS=Mus
musculus OX=10090 GN=Mapk12 PE=1 SV=1
Length=367
Score = 212 bits (540), Expect = 2e-59, Method: Composition-based stats.
Identities = 62/302 (21%), Positives = 124/302 (41%), Gaps = 36/302 (12%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLY 955
+ ++ +G G +G V + TG VA+K L + +E+ +L+ +
Sbjct 27 YQDLQPVGSGAYGAVC----SAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMR 82
Query 956 HEHIIKYKGCCEDQ----GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011
HE++I LVM ++ L + ++ ++ Q+ +G+
Sbjct 83 HENVIGLLDVFTPDESLDDFTDFYLVMPFM-GTDLGKLMKHETLSEDRIQFLVYQMLKGL 141
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
Y+HA IHRDL N+ ++ D +KI DFGLA+ Y V ++ APE
Sbjct 142 KYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVV------TRWYRAPE 195
Query 1072 CLKEY-KFYYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGI 1114
+ + ++ D+WS G + E++T + +PP +F++ +
Sbjct 196 VILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKITGTPPPEFVQKLQS 255
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTV 1172
A+ + + L E LE+ + + +L++ +A R T + P +++
Sbjct 256 AEAKNYMEGLPE-LEKKDFASVLTNASPQAVNLLERMLVLDAEQRVTAAEALTHPYFESL 314
Query 1173 HE 1174
+
Sbjct 315 RD 316
Score = 127 bits (318), Expect = 3e-30, Method: Composition-based stats.
Identities = 34/219 (16%), Positives = 70/219 (32%), Gaps = 20/219 (9%)
Query 632 DRGQELRVVLKVL-DPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPEN------ 683
D +V +K L P ++ A Y L+ + H ++ + V
Sbjct 46 DSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDESLDDFTDF 105
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+V ++ L ++ E + + Q+ L Y+ ++H ++ N+
Sbjct 106 YLVMPFM-GTDLGKLMKHE--TLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNL--- 159
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL-APECLPGGANSLSTAMDKWGFGA 802
A +K+ D G+ A S W APE + + +D W G
Sbjct 160 ----AVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMR-YTQTVDIWSVGC 214
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL 841
+ E+ + + + + P +L
Sbjct 215 IMAEMITGKILFKGNDHLDQLKEIMKITGTPPPEFVQKL 253
>sp|Q9SSL9|PEPR1_ARATH Leucine-rich repeat receptor-like protein
kinase PEPR1 OS=Arabidopsis thaliana OX=3702 GN=PEPR1 PE=1
SV=1
Length=1123
Score = 227 bits (578), Expect = 2e-59, Method: Composition-based stats.
Identities = 68/305 (22%), Positives = 125/305 (41%), Gaps = 28/305 (9%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+ +G G G V G+G++ AVK L + +EID + + H
Sbjct 828 NEKYTIGRGAHGIVYRASL-----GSGKVYAVKRLVFASHIRANQSMMREIDTIGKVRHR 882
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMA 1012
++IK +G + + ++ Y+P GSL D L + + + A + G+A
Sbjct 883 NLIKLEGFWLRKDDG--LMLYRYMPKGSLYDVLHGVSPKENVLDWSARYNVALGVAHGLA 940
Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH +HRD+ N+L+D+D IGDFGLA+ + + + A
Sbjct 941 YLHYDCHPPIVHRDIKPENILMDSDLEPHIGDFGLARLLDDS---TVSTATVTGTTGYIA 997
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR------ 1123
PE + SDV+S+GV L EL+T + + +++ + ++
Sbjct 998 PENAFKTVRGRESDVYSYGVVLLELVTRKRAVDKSFPESTDIVSWVRSALSSSNNNVEDM 1057
Query 1124 LTELLERGERLPRPDKCPCE----VYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+T +++ D E V L +C + + + RPT + + +L+ V +
Sbjct 1058 VTTIVDPILVDELLDSSLREQVMQVTELALSCTQQDPAMRPTMRDAVKLLEDVKHLARSC 1117
Query 1180 APSVF 1184
+
Sbjct 1118 SSDSV 1122
Score = 163 bits (412), Expect = 2e-39, Method: Composition-based stats.
Identities = 45/240 (19%), Positives = 79/240 (33%), Gaps = 45/240 (19%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ + +G+G VY L GSG +K L
Sbjct 823 ATDNLNEKYTIGRGAHGIVYRASL---GSGKVY----------------------AVKRL 857
Query 645 D-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-- 701
SH + + +V H +L + G +R + +M+ Y+ G L L
Sbjct 858 VFASHIRANQSMMREIDTIGKVRHRNLIKLEGFWLRKDDGLMLYRYMPKGSLYDVLHGVS 917
Query 702 -ERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ + + + VA +A L+YL + +VH ++ NIL+ +
Sbjct 918 PKENVLDWSARYNVALGVAHGLAYLHYDCHPPIVHRDIKPENILMDSDLEPH-------I 970
Query 758 SDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
D G+ +S ++APE D + +G LLE+ A
Sbjct 971 GDFGLARLLDDSTVSTATVTGTTGYIAPENAFKTVR--GRESDVYSYGVVLLELVTRKRA 1028
>sp|Q8NG66|NEK11_HUMAN Serine/threonine-protein kinase Nek11 OS=Homo
sapiens OX=9606 GN=NEK11 PE=1 SV=2
Length=645
Score = 220 bits (560), Expect = 2e-59, Method: Composition-based stats.
Identities = 66/306 (22%), Positives = 118/306 (39%), Gaps = 28/306 (9%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
+ A + ++ P R + LG G FG V L G V
Sbjct 1 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKV- 59
Query 929 VKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
+K + + P E +L L H I+K+ +Q + ++ EY L
Sbjct 60 LKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQD--NFCIITEYCEGRDLD 117
Query 988 DYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
D + + Q++ + Q+ G+ Y+H + +HRDL ++NV L N+ +KIGDF
Sbjct 118 DKIQEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNL-LKIGDF 176
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
G+++ + + + +PE LK + SD+WS LYE+
Sbjct 177 GVSRLLMGSCDLATTLT---GTPHYMSPEALKHQGYDTKSDIWSLACILYEMC------- 226
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
+ A L + + G+ P++ P E+ +M++ S RP+
Sbjct 227 --------CMNHAFAGSNFLSIVLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSA 278
Query 1163 ENLIPI 1168
++ I
Sbjct 279 IEILKI 284
Score = 177 bits (448), Expect = 6e-45, Method: Composition-based stats.
Identities = 66/386 (17%), Positives = 116/386 (30%), Gaps = 58/386 (15%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LG G+ VY RG+EL+V LK + +
Sbjct 34 KLGSGSFGTVYL--------------------VSDKKAKRGEELKV-LKEISVGELNPNE 72
Query 654 AFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER---GHVPM 708
A L+S++ H + H V ++TEY E LD ++ + P
Sbjct 73 TVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPE 132
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ QL + Y+ + ++H ++ +N+ L L K+ D GV +
Sbjct 133 NQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLL--------KIGDFGVSRLLMG 184
Query 769 R----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+++PE L T D W L E+C A S S
Sbjct 185 SCDLATTLTGTPHYMSPEALKH--QGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVL 242
Query 825 HFYQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT--------RLQPHNLA 875
+ LPE +L + L P+ RPS IL+ + +
Sbjct 243 KIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSEMT 302
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA---VKAL 932
+ + + ++ L +V A + L
Sbjct 303 LEDKNLDCQKEAAHIINAMQKRIHLQTLR--ALSEVQKMTPRERMRLRKLQAADEKARKL 360
Query 933 KADCGPQHRSGWKQEIDILRTLYHEH 958
K ++ K+ ++ L +
Sbjct 361 KKIVEEKYEENSKR----MQELRSRN 382
>sp|A2YNT8|SAPK2_ORYSI Serine/threonine-protein kinase SAPK2 OS=Oryza
sativa subsp. indica OX=39946 GN=SAPK2 PE=2 SV=2
Length=339
Score = 211 bits (537), Expect = 2e-59, Method: Composition-based stats.
Identities = 71/276 (26%), Positives = 115/276 (42%), Gaps = 26/276 (9%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+ I+D+G G+FG L + T E+ AVK + + G + ++EI R+
Sbjct 1 MERYEVIKDIGSGNFGVAKLV----RDVRTKELFAVKFI--ERGQKIDENVQREIMNHRS 54
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012
L H +I+++K L +VMEY G L + + + F QQ+ G++
Sbjct 55 LRHPNIVRFKEVVLTPTH--LAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVS 112
Query 1013 YLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
Y H+ HRDL N LLD +KI DFG +K + + + +P + AP
Sbjct 113 YCHSMQICHRDLKLENTLLDGSIAPRLKICDFGYSK---SSVLHSQPKSTVGTPA-YIAP 168
Query 1071 ECLKEYKFYYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E L ++ DVWS GVTLY +L + P + + +T +L
Sbjct 169 EVLARKEYDGKVADVWSCGVTLYVMLVGAYPFEDPD----------EPRNFRKTITRILS 218
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+P + E HL+ + R T +
Sbjct 219 VQYMVPDYVRVSMECRHLLSRIFVANPEQRITIPEI 254
Score = 156 bits (394), Expect = 2e-40, Method: Composition-based stats.
Identities = 50/276 (18%), Positives = 87/276 (32%), Gaps = 23/276 (8%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
RD + +K ++ I + H ++ V + +V EY
Sbjct 22 RDVRTKELFAVKFIERG-QKIDENVQREIMNHRSLRHPNIVRFKEVVLTPTHLAIVMEYA 80
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L + G QQL S +SY + + H ++ N LL
Sbjct 81 AGGELFERI-CSAGRFSEDEARFFFQQLISGVSYCHSMQICHRDLKLENTLLD-----GS 134
Query 751 TSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+P +K+ D G ++ + V ++APE L D W G TL +
Sbjct 135 IAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLARKEYD-GKVADVWSCGVTLYVM 193
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLT-------YEPTQRPS 858
G P + P E +F + R+ + P ++ +C P QR +
Sbjct 194 LV-GAYPFED--PDEPRNFRKTITRILSVQYMVPDYVRVSMECRHLLSRIFVANPEQRIT 250
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894
I L+ + +D +
Sbjct 251 IPEIKNHPWFLKNLPIEMTDEYQMSVQMNDINTPSQ 286
>sp|A0A509AQE6|CDPK5_PLABA Calcium-dependent protein kinase 5
OS=Plasmodium berghei (strain Anka) OX=5823 GN=CDPK5 PE=1 SV=1
Length=562
Score = 218 bits (555), Expect = 2e-59, Method: Composition-based stats.
Identities = 71/302 (24%), Positives = 116/302 (38%), Gaps = 34/302 (11%)
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932
D + ++ + K Y LG+G +G V N TG+ A+K +
Sbjct 94 PYFDRSQIVQETILMNNDDLEKLYELDKYKLGKGSYGNVV----KAINKKTGQAKAIKII 149
Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992
+ K+EI I++ + H +IIK ED + L LV+E G L D + +
Sbjct 150 DKK-RINNIERLKREILIMKQMDHPNIIKLYEVYEDN--EKLYLVLELCTGGELFDKIVK 206
Query 993 H-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAV 1048
H S + +QI +AY H+++ IHRDL N+L +D ++I D+G A
Sbjct 207 HGSFSEYETYKIMKQIFSALAYCHSKNIIHRDLKPENILYVDSSDDSPIQIIDWGFASKC 266
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
H V ++ APE LK K+ D+WS GV +Y LL
Sbjct 267 MNNHNLKSV----VGTPYYIAPEILKG-KYDKKCDIWSSGVIMYILLCGYPPF------- 314
Query 1109 LELIGIAQGQMTVLRLTELLERGERL---PRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ + +++GE + K + L+ C R +
Sbjct 315 --------NGKNNDDILKKVKKGEFVFDSNYWSKISLDAKELICECLNYNYKERIDVHKI 366
Query 1166 IP 1167
+
Sbjct 367 VN 368
Score = 187 bits (474), Expect = 8e-49, Method: Composition-based stats.
Identities = 55/319 (17%), Positives = 103/319 (32%), Gaps = 41/319 (13%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LG+G+ NV + + G +K++D +
Sbjct 123 KLGKGSYGNVVKAINKKTGQAK------------------------AIKIIDKKRINNIE 158
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
+M Q+ H ++ ++ V + +V E G L + + G
Sbjct 159 RLKREILIMKQMDHPNIIKLYEVYEDNEKLYLVLELCTGGELFDKIVKH-GSFSEYETYK 217
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR---E 770
+ +Q+ SAL+Y +KN++H ++ NIL + I++ D G ++ +
Sbjct 218 IMKQIFSALAYCHSKNIIHRDLKPENIL----YVDSSDDSPIQIIDWGFASKCMNNHNLK 273
Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830
V ++APE L G D W G + I G P ++ + ++
Sbjct 274 SVVGTPYYIAPEILKG---KYDKKCDIWSSGVIMY-ILLCGYPPFNGKNNDDILKKVKKG 329
Query 831 H-----RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885
L +CL Y +R I+ ++ N + S
Sbjct 330 EFVFDSNYWSKISLDAKELICECLNYNYKERIDVHKIVNHKWFIKFKNYNHITINKHLSK 389
Query 886 ASDPTVFHKRYLKKIRDLG 904
L KI+ L
Sbjct 390 ELIEKFKKFHKLCKIKKLA 408
>sp|P54644|KRAC_DICDI RAC family serine/threonine-protein kinase
homolog OS=Dictyostelium discoideum OX=44689 GN=pkbA PE=1
SV=1
Length=444
Score = 214 bits (546), Expect = 2e-59, Method: Composition-based stats.
Identities = 65/290 (22%), Positives = 110/290 (38%), Gaps = 32/290 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960
+G+G FGKV TGE+ A+K L +H E +IL+ + H ++
Sbjct 126 VGKGSFGKV----IQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSERNILQKINHPFLV 181
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHY 1019
Q E L +++YV G L +L + ++ + +I + +LH
Sbjct 182 NLNYSF--QTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLSGV 239
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
I+RDL N+LL N+ + + DFGL K + APE L+ +
Sbjct 240 IYRDLKPENLLLTNEGHICMTDFGLCK--EGLLTPTDKTGTFCGTPEYLAPEVLQGNGYG 297
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
D WSFG LYE+LT + + + + + +L P
Sbjct 298 KQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMME----------------KLSFPHF 341
Query 1140 CPCEVYHLMKNCWETEASFR---PTFENLIPILKTV--HEKYQGQAPSVF 1184
+ L++ E + R P P +++ + +Q P F
Sbjct 342 ISPDARSLLEQLLERDPEKRLADPNLIKRHPFFRSIDWEQLFQKNIPPPF 391
Score = 162 bits (409), Expect = 2e-41, Method: Composition-based stats.
Identities = 55/317 (17%), Positives = 112/317 (35%), Gaps = 44/317 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+V + L+ +G+G+ V ++R + +G+ +
Sbjct 113 EKVGVADFELLNLVGKGSFGKVI--QVRKKDTGEVY----------------------AM 148
Query 642 KVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
KVL H H+ +++ +++H L ++ + + +YV G L
Sbjct 149 KVLSKKHIVEHNEVEHTLSERNILQKINHPFLVNLNYSFQTEDKLYFILDYVNGGELFYH 208
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
L++++ ++ AL +L +++ ++ N+LL G I ++
Sbjct 209 LQKDK-KFTEDRVRYYGAEIVLALEHLHLSGVIYRDLKPENLLLTNEG-------HICMT 260
Query 759 DPGVGLGAL-----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
D G+ L +LAPE L G N +D W FG+ L E+ G
Sbjct 261 DFGLCKEGLLTPTDKTGTFCGTPEYLAPEVLQG--NGYGKQVDWWSFGSLLYEML-TGLP 317
Query 814 PLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
P ++ E + P P +L Q L +P +R + +++ +
Sbjct 318 PFYNQDVQEMYRKIMMEKLSFPHFISPDARSLLEQLLERDPEKRLADPNLIKRHPFFRSI 377
Query 873 NLADVLTVNPDSPASDP 889
+ + N P
Sbjct 378 DWEQLFQKNIPPPFIPN 394
>sp|Q4PC06|HOG1_USTMA Mitogen-activated protein kinase HOG1 OS=Ustilago
maydis (strain 521 / FGSC 9021) OX=237631 GN=HOG1
PE=3 SV=1
Length=358
Score = 211 bits (538), Expect = 2e-59, Method: Composition-based stats.
Identities = 66/283 (23%), Positives = 109/283 (39%), Gaps = 29/283 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T VA+K + K P +E+ +L+ + HE+I
Sbjct 24 QPVGMGAFGLVC----SANDQLTSTSVAIKKIMKPFSTPVLSKRTYRELKLLKHIRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
A DVWS G E+L + + EL+G ++ LR +
Sbjct 192 DVAVDVWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDEVIKTICSENTLRFVQ 251
Query 1127 LLERGERLPRPD---KCPCEVYHLMKNCWETEASFRPTFENLI 1166
L + ER+P L++ + R + +
Sbjct 252 SLPKRERVPFSQKFKNADPMALDLLEKMLVFDPRTRISAAEAL 294
Score = 137 bits (345), Expect = 1e-33, Method: Composition-based stats.
Identities = 37/231 (16%), Positives = 76/231 (33%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
V+E D + M + D+ V +K ++ P ++ Y
Sbjct 10 FGTVFE---VTTRYVDLQPVGMGAFGLVCSANDQLTSTSVAIKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHIRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + A+D W G E+ +G+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVAVDVWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225
>sp|Q8CEQ0|CDKL1_MOUSE Cyclin-dependent kinase-like 1 OS=Mus musculus
OX=10090 GN=Cdkl1 PE=2 SV=1
Length=352
Score = 211 bits (538), Expect = 2e-59, Method: Composition-based stats.
Identities = 63/293 (22%), Positives = 118/293 (40%), Gaps = 29/293 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960
+GEG +G V + N TG++VA+K L+ + P + +EI +L+ L H +++
Sbjct 9 KIGEGSYGVV----FKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLV 64
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ + L LV EY L + + + + Q + + + H +
Sbjct 65 NLLEVFRRK--RRLHLVFEYCDHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKHNC 122
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEYKF 1078
IHRD+ N+L+ +K+ DFG A+ + +YY D + ++ +PE L + ++
Sbjct 123 IHRDVKPENILITKQSAIKLCDFGFARLLTGPGDYY---TDYVATRWYRSPELLVGDTQY 179
Query 1079 YYASDVWSFGVTLYELLTHCD-----SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
DVW+ G ELL+ S + +G + + G +
Sbjct 180 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVK 239
Query 1134 LPRPD----------KCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHE 1174
+P P+ +K C + + R T E L+ P ++ E
Sbjct 240 IPDPEDMETLELKFPNISYSALGFLKGCLHMDPAERLTCEQLLQHPYFDSIRE 292
Score = 155 bits (391), Expect = 7e-40, Method: Composition-based stats.
Identities = 49/250 (20%), Positives = 87/250 (35%), Gaps = 40/250 (16%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ ++ +G+G+ V++ R R G V +K
Sbjct 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQ------------------------IVAIKRFL 36
Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ D I ++ Q+ H +L + V R +V EY +H L R +R
Sbjct 37 ETEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQR 96
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
G VP + Q A+++ N +H +V NIL+ + IKL D G
Sbjct 97 G-VPEPLVKNITWQTLQAVNFCHKHNCIHRDVKPENILITKQSA-------IKLCDFGFA 148
Query 764 LGAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ V + +PE L G +D W G E+ G +S
Sbjct 149 RLLTGPGDYYTDYVATRWYRSPELLV-GDTQYGPPVDVWAIGCVFAELLS-GVPLWPGKS 206
Query 820 PSEKEHFYQR 829
++ + ++
Sbjct 207 DVDQLYLIRK 216
>sp|Q7TSC3|NEK5_MOUSE Serine/threonine-protein kinase Nek5 OS=Mus
musculus OX=10090 GN=Nek5 PE=2 SV=1
Length=627
Score = 219 bits (559), Expect = 2e-59, Method: Composition-based stats.
Identities = 66/285 (23%), Positives = 121/285 (42%), Gaps = 33/285 (12%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
I+ +GEG FGKV L + +K + + + K E+ +L
Sbjct 1 MDNFHLIKIIGEGTFGKVYL----AKDKSESSHCVIKEISL---TKEKEASKNEVILLAR 53
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEG 1010
+ H +I+ + ++ G L +VMEY G L + R Q+L + QI G
Sbjct 54 MEHPNIVTFFSSFQENG--RLFIVMEYCDGGDLMQRIQRQRGVMFSEDQILCWFVQISLG 111
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ ++H + +HRD+ ++N+ L + +V K+GDFG A+ + + E + + ++ +
Sbjct 112 LKHIHDRKILHRDIKSQNIFLSKNGMVAKLGDFGTARTLNDSME---LAQTCAGTPYYLS 168
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE + + +D+WS G LYEL T +S L L +
Sbjct 169 PEICQNRPYNNKTDIWSLGCVLYELCTLKHPFESNNFHHLVL---------------KIC 213
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTV 1172
+G P ++ L+ + RP+ +L+ P L+T+
Sbjct 214 QGRVAPISPHFSRDLQSLIPQLFRVSPQDRPSVTSLLKRPFLETL 258
Score = 175 bits (443), Expect = 2e-44, Method: Composition-based stats.
Identities = 48/283 (17%), Positives = 93/283 (33%), Gaps = 40/283 (14%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ +G+GT VY + D+ + V+K +
Sbjct 1 MDNFHLIKIIGEGTFGKVYLAK------------------------DKSESSHCVIKEIS 36
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ A L++++ H ++ +V EY + G L ++R+RG
Sbjct 37 LTKEKEASK--NEVILLARMEHPNIVTFFSSFQENGRLFIVMEYCDGGDLMQRIQRQRGV 94
Query 706 -VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ Q++ L ++ ++ ++H ++ +NI L++ G+ KL D G
Sbjct 95 MFSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNGM------VAKLGDFGTAR 148
Query 765 GALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+ +L+PE + D W G L E+C +
Sbjct 149 TLNDSMELAQTCAGTPYYLSPEICQN--RPYNNKTDIWSLGCVLYELCTLKHPFESNNFH 206
Query 821 SEKEHFYQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
Q R + L +L Q P RPS ++
Sbjct 207 HLVLKICQGRVAPISPHFSRDLQSLIPQLFRVSPQDRPSVTSL 249
>sp|F4KA51|LRL23_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE
PROTEIN KINASE-like 2.3 OS=Arabidopsis thaliana
OX=3702 GN=LRK10L-2.3 PE=3 SV=2
Length=620
Score = 219 bits (558), Expect = 2e-59, Method: Composition-based stats.
Identities = 63/277 (23%), Positives = 111/277 (40%), Gaps = 23/277 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V G VAVK LK + + E+ + H +I+
Sbjct 320 VGRGGFGTVYRGRLR-----DGRKVAVKVLK--DSKGNCEDFINEVASMSQTSHVNIVTL 372
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH---AQHY 1019
G C + +++ ++ E++ GSL L ++ ++ L A + G+ YLH
Sbjct 373 LGFCYEGSKRA--IIYEFLENGSLDQSL---NLDVSTLYGIALGVARGLEYLHYGCKTRI 427
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL--KEYK 1077
+H D+ +NVLLD + K+ DFGLAK E E D + + APE
Sbjct 428 VHFDIKPQNVLLDENLRPKVADFGLAKLC-EKQESILSLLDTRGTIGYIAPELFSRMYGS 486
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQ----SPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ SDV+S+G+ + E++ + + P + T LL G
Sbjct 487 VSHKSDVYSYGMLVLEMIGARNKERVQNADPNNSSAYFPDWIYKDLENFDNTRLLGDGLT 546
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
++ + C + S RP+ ++ +++
Sbjct 547 REEEKNA-KKMILVGLWCIQFRPSDRPSMNKVVEMME 582
Score = 202 bits (514), Expect = 1e-53, Method: Composition-based stats.
Identities = 63/320 (20%), Positives = 117/320 (37%), Gaps = 66/320 (21%)
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
L ++ ++ + + +G+G VY GRLR
Sbjct 300 TLRGYNYKQIKKITKSFTEVVGRGGFGTVYRGRLRDGR---------------------- 337
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+V +KVL S + F + MSQ SH ++ + G C G + ++ E++E+G
Sbjct 338 ---KVAVKVLKDSKGNC-EDFINEVASMSQTSHVNIVTLLGFCYEGSKRAIIYEFLENGS 393
Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGT 751
LD L ++ ++ +A +A L YL +VH ++ +N+LL
Sbjct 394 LDQSL-----NLDVSTLYGIALGVARGLEYLHYGCKTRIVHFDIKPQNVLLDE------- 441
Query 752 SPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ K++D G+ LS + I ++APE S+S D + +G +L
Sbjct 442 NLRPKVADFGLAKLCEKQESILSLLDTRGTIGYIAPELFSRMYGSVSHKSDVYSYGMLVL 501
Query 806 EIC---------------FDGEAPLQSRSPSEKEH----FYQRQHRLPEPSCPQLATLTS 846
E+ P E R E + ++ +
Sbjct 502 EMIGARNKERVQNADPNNSSAYFPDWIYKDLENFDNTRLLGDGLTREEEKNAKKMILVGL 561
Query 847 QCLTYEPTQRPSFRTILRDL 866
C+ + P+ RPS ++ +
Sbjct 562 WCIQFRPSDRPSMNKVVEMM 581
>sp|Q9M1G4|LRK15_ARATH Probable L-type lectin-domain containing
receptor kinase I.5 OS=Arabidopsis thaliana OX=3702 GN=LECRK15
PE=2 SV=2
Length=674
Score = 220 bits (561), Expect = 2e-59, Method: Composition-based stats.
Identities = 75/300 (25%), Positives = 122/300 (41%), Gaps = 22/300 (7%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
+ + K R LG G FG+V + + VAVK + D G Q
Sbjct 327 YGTHRFSYKSLYIATKGFHKDRFLGRGGFGEVYRG-----DLPLNKTVAVKRVSHD-GEQ 380
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIG 996
+ E+ +++L H +++ G C +GE L LV EY+P GSL +L +
Sbjct 381 GMKQFVAEVVSMKSLKHRNLVPLLGYCRRKGE--LLLVSEYMPNGSLDQHLFDDQSPVLS 438
Query 997 LAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+Q + + I + YLH Q +HRD+ A NV+LD + ++GDFG+A+ G
Sbjct 439 WSQRFVILKGIASALFYLHTEAEQVVLHRDIKASNVMLDAELNGRLGDFGMARFHDHGGN 498
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
V + APE + +DV++FGV L E+ + +E
Sbjct 499 AATT--AAVGTVGYMAPELI-TMGASTITDVYAFGVFLLEVACGRKPVEFGVQ--VEKRF 553
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170
+ + + LL+ + + P EV +MK C RP ++ L
Sbjct 554 LIKWVCECWKKDSLLDAKDPRLGEEFVPEEVELVMKLGLLCTNIVPESRPAMGQVVLYLS 613
Score = 218 bits (554), Expect = 2e-58, Method: Composition-based stats.
Identities = 60/305 (20%), Positives = 111/305 (36%), Gaps = 61/305 (20%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
+ K + LG+G VY G L + + V +K
Sbjct 339 IATKGFHKDRFLGRGGFGEVYRGDLPLNKT-------------------------VAVKR 373
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ F M + H +L + G C R E ++V+EY+ +G LD L ++
Sbjct 374 VSHDGEQGMKQFVAEVVSMKSLKHRNLVPLLGYCRRKGELLLVSEYMPNGSLDQHLFDDQ 433
Query 704 GH-VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ + + V+ + +ASAL YL + ++H ++ N++L +L D
Sbjct 434 SPVLSWSQRFVILKGIASALFYLHTEAEQVVLHRDIKASNVMLD-------AELNGRLGD 486
Query 760 PGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
G+ G + V + ++APE + GA++++ D + FG LLE+ +
Sbjct 487 FGMARFHDHGGNAATTAAVGTVGYMAPELITMGASTIT---DVYAFGVFLLEVACGRKPV 543
Query 815 LQSRSPSEKEHFYQ-------------RQHRLPEPSCPQLATLTSQ----CLTYEPTQRP 857
++ + RL E P+ L + C P RP
Sbjct 544 EFGVQVEKRFLIKWVCECWKKDSLLDAKDPRLGEEFVPEEVELVMKLGLLCTNIVPESRP 603
Query 858 SFRTI 862
+ +
Sbjct 604 AMGQV 608
>sp|Q63538|MK12_RAT Mitogen-activated protein kinase 12 OS=Rattus
norvegicus OX=10116 GN=Mapk12 PE=1 SV=1
Length=367
Score = 212 bits (539), Expect = 2e-59, Method: Composition-based stats.
Identities = 62/302 (21%), Positives = 124/302 (41%), Gaps = 36/302 (12%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLY 955
+ ++ +G G +G V + TG VA+K L + +E+ +L+ +
Sbjct 27 YQDLQPVGSGAYGAVC----SAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMR 82
Query 956 HEHIIKYKGCCEDQ----GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011
HE++I LVM ++ L + ++ ++ Q+ +G+
Sbjct 83 HENVIGLLDVFTPDETLDDFTDFYLVMPFM-GTDLGKLMKHETLSEDRIQFLVYQMLKGL 141
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
Y+HA IHRDL N+ ++ D +KI DFGLA+ Y V ++ APE
Sbjct 142 KYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVV------TRWYRAPE 195
Query 1072 CLKEY-KFYYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGI 1114
+ + ++ D+WS G + E++T + +PP +F++ +
Sbjct 196 VILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKVTGTPPPEFVQKLQS 255
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTV 1172
A+ + + L E LE+ + + +L++ +A R T + P +++
Sbjct 256 AEAKNYMEGLPE-LEKKDFASVLTNASPQAVNLLEKMLVLDAEQRVTAAEALAHPYFESL 314
Query 1173 HE 1174
+
Sbjct 315 RD 316
Score = 127 bits (319), Expect = 3e-30, Method: Composition-based stats.
Identities = 34/219 (16%), Positives = 70/219 (32%), Gaps = 20/219 (9%)
Query 632 DRGQELRVVLKVL-DPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPEN------ 683
D +V +K L P ++ A Y L+ + H ++ + V
Sbjct 46 DSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDF 105
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+V ++ L ++ E + + Q+ L Y+ ++H ++ N+
Sbjct 106 YLVMPFM-GTDLGKLMKHE--TLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNL--- 159
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL-APECLPGGANSLSTAMDKWGFGA 802
A +K+ D G+ A S W APE + + +D W G
Sbjct 160 ----AVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMR-YTQTVDIWSVGC 214
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL 841
+ E+ + + + + P +L
Sbjct 215 IMAEMITGKILFKGNDHLDQLKEIMKVTGTPPPEFVQKL 253
>sp|Q0D4J7|SAPK2_ORYSJ Serine/threonine-protein kinase SAPK2 OS=Oryza
sativa subsp. japonica OX=39947 GN=SAPK2 PE=1 SV=1
Length=339
Score = 211 bits (536), Expect = 2e-59, Method: Composition-based stats.
Identities = 70/276 (25%), Positives = 112/276 (41%), Gaps = 26/276 (9%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+ I+D+G G+FG L + T E+ AVK + + G + ++EI R+
Sbjct 1 MERYEVIKDIGSGNFGVAKLV----RDVRTKELFAVKFI--ERGQKIDENVQREIMNHRS 54
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012
L H +I+++K L +VMEY G L + + + F QQ+ G++
Sbjct 55 LRHPNIVRFKEVVLTPTH--LAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVS 112
Query 1013 YLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
Y H+ HRDL N LLD +KI DFG +K + + + AP
Sbjct 113 YCHSMQICHRDLKLENTLLDGSIAPRLKICDFGYSK----SSLLHSQPKSTVGTPAYIAP 168
Query 1071 ECLKEYKFYYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E L ++ DVWS GVTLY +L + P + + +T +L
Sbjct 169 EVLARKEYDGKVADVWSCGVTLYVMLVGAYPFEDPD----------EPRNFRKTITRILS 218
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+P + E HL+ + R T +
Sbjct 219 VQYMVPDYVRVSMECRHLLSRIFVANPEQRITIPEI 254
Score = 156 bits (395), Expect = 2e-40, Method: Composition-based stats.
Identities = 51/276 (18%), Positives = 87/276 (32%), Gaps = 23/276 (8%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
RD + +K ++ I + H ++ V + +V EY
Sbjct 22 RDVRTKELFAVKFIERG-QKIDENVQREIMNHRSLRHPNIVRFKEVVLTPTHLAIVMEYA 80
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L + G QQL S +SY + + H ++ N LL
Sbjct 81 AGGELFERI-CSAGRFSEDEARFFFQQLISGVSYCHSMQICHRDLKLENTLLD-----GS 134
Query 751 TSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+P +K+ D G +L + V ++APE L D W G TL +
Sbjct 135 IAPRLKICDFGYSKSSLLHSQPKSTVGTPAYIAPEVLARKEYD-GKVADVWSCGVTLYVM 193
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLT-------YEPTQRPS 858
G P + P E +F + R+ + P ++ +C P QR +
Sbjct 194 LV-GAYPFED--PDEPRNFRKTITRILSVQYMVPDYVRVSMECRHLLSRIFVANPEQRIT 250
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894
I L+ + +D +
Sbjct 251 IPEIKNHPWFLKNLPIEMTDEYQMSVQMNDINTPSQ 286
>sp|Q2RBF0|CIPKF_ORYSJ CBL-interacting protein kinase 15 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK15 PE=2 SV=1
Length=434
Score = 214 bits (544), Expect = 2e-59, Method: Composition-based stats.
Identities = 61/267 (23%), Positives = 113/267 (42%), Gaps = 27/267 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960
LG+G FGKV N + + VA+K + + ++EI +R + H++I+
Sbjct 18 LGKGTFGKVHY----ARNLESNQSVAIKMMDKQQILKVGLSEQIRREITTMRLVAHKNIV 73
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ + + + VMEYV G L + + R + + QQ+ + Y H++
Sbjct 74 QLHEVMATRNK--IYFVMEYVKGGELFEKVAKRGKLTEVVAHKYFQQLISAVDYCHSRGV 131
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
HRDL N+LLD + +K+ DFGL+ + + +P + APE + + +
Sbjct 132 YHRDLKPENLLLDENENLKVSDFGLSALSESKRQDGLLHTTCGTPA-YVAPEVISKIGYD 190
Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SD+WS GV L+ L+ Q P ++ + ++ GE P
Sbjct 191 GAKSDIWSCGVILFVLVAGYLPFQGP---------------NLMEMYRKIQHGE-FRCPG 234
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENL 1165
++ L+ + S R + + +
Sbjct 235 WFSRKLQKLLYKIMDPNPSTRISIQKI 261
Score = 181 bits (458), Expect = 6e-48, Method: Composition-based stats.
Identities = 56/296 (19%), Positives = 100/296 (34%), Gaps = 44/296 (15%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
++ + LG+GT V+ R V +K
Sbjct 6 KILMERYELGRLLGKGTFGKVHYARNLESNQS------------------------VAIK 41
Query 643 VLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
++D ++ + M V+H ++ +H V + V EYV+ G L +
Sbjct 42 MMDKQQILKVGLSEQIRREITTMRLVAHKNIVQLHEVMATRNKIYFVMEYVKGGELFEKV 101
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+RG + QQL SA+ Y ++ + H ++ N+LL + +K+SD
Sbjct 102 -AKRGKLTEVVAHKYFQQLISAVDYCHSRGVYHRDLKPENLLLDE-------NENLKVSD 153
Query 760 PGVGLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ + S+ ++APE + D W G L + G
Sbjct 154 FGLSALSESKRQDGLLHTTCGTPAYVAPEVISKIGYD-GAKSDIWSCGVIL-FVLVAGYL 211
Query 814 PLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
P Q + E + R P +L L + + P+ R S + I
Sbjct 212 PFQGPNLMEMYRKIQHGEFRCPGWFSRKLQKLLYKIMDPNPSTRISIQKIKESTWF 267
>sp|Q96PY6|NEK1_HUMAN Serine/threonine-protein kinase Nek1 OS=Homo
sapiens OX=9606 GN=NEK1 PE=1 SV=2
Length=1258
Score = 227 bits (578), Expect = 2e-59, Method: Composition-based stats.
Identities = 63/278 (23%), Positives = 121/278 (44%), Gaps = 28/278 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILR 952
+++ +GEG FGK L + G +K + + + R ++E+ +L
Sbjct 1 MEKYVRLQKIGEGSFGKAILV----KSTEDGRQYVIKEINISRMSSKEREESRREVAVLA 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICE 1009
+ H +I++Y+ E+ G SL +VM+Y G L + Q+L + QIC
Sbjct 57 NMKHPNIVQYRESFEENG--SLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICL 114
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ ++H + +HRD+ ++N+ L D V++GDFG+A+ + E R ++ +
Sbjct 115 ALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELART---CIGTPYYLS 171
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE + + SD+W+ G LYEL T + ++ K L L +
Sbjct 172 PEICENKPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVL---------------KII 216
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
G P ++ L+ ++ RP+ +++
Sbjct 217 SGSFPPVSLHYSYDLRSLVSQLFKRNPRDRPSVNSILE 254
Score = 160 bits (404), Expect = 2e-38, Method: Composition-based stats.
Identities = 44/283 (16%), Positives = 92/283 (33%), Gaps = 37/283 (13%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ +L +G+G+ LV + G++ + +
Sbjct 1 MEKYVRLQKIGEGSFGK----------------------AILVKSTEDGRQYVIKEINIS 38
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
++++ + H ++ +V +Y E G L + ++G
Sbjct 39 RMSSKEREESRREVAVLANMKHPNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGV 98
Query 706 V-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + Q+ AL ++ ++ ++H ++ +NI L + G ++L D G+
Sbjct 99 LFQEDQILDWFVQICLALKHVHDRKILHRDIKSQNIFLTKDG-------TVQLGDFGIAR 151
Query 765 GALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS-RS 819
S + +L+PE + D W G L E+C A
Sbjct 152 VLNSTVELARTCIGTPYYLSPEICEN--KPYNNKSDIWALGCVLYELCTLKHAFEAGSMK 209
Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
+ + L +L SQ P RPS +I
Sbjct 210 NLVLKIISGSFPPVSLHYSYDLRSLVSQLFKRNPRDRPSVNSI 252
>sp|Q6C7U8|PHO85_YARLI Negative regulator of the PHO system OS=Yarrowia
lipolytica (strain CLIB 122 / E 150) OX=284591 GN=PHO85
PE=3 SV=1
Length=294
Score = 209 bits (532), Expect = 3e-59, Method: Composition-based stats.
Identities = 54/217 (25%), Positives = 99/217 (46%), Gaps = 15/217 (7%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+ +++ LGEG + V Y N TG++VA+K + D S +EI +
Sbjct 1 MNTSSQFQQLEKLGEGTYATV----YKGRNRTTGQLVALKEINLDSEEGTPSTAIREISL 56
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQ 1006
++ L HE+I+ E L LV EY+ L+ ++ + ++ Q+ F Q
Sbjct 57 MKELKHENIVTLYDVI--HTENKLNLVFEYMDK-DLKKFMDTNGNKGALETKQVKWFMYQ 113
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+ G+ + H +HRDL +N+L++ +K+ DFGLA+A + ++
Sbjct 114 LLRGILFCHDNRVLHRDLKPQNLLINAKGQLKLADFGLARAFGIP---VNTFSNEVVTLW 170
Query 1067 WYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQ 1102
+ AP+ L + + + D+WS G + E+ T
Sbjct 171 YRAPDVLLGSRTYSTSIDIWSAGCIMAEMFTGRPLFP 207
Score = 175 bits (444), Expect = 2e-47, Method: Composition-based stats.
Identities = 56/322 (17%), Positives = 121/322 (38%), Gaps = 40/322 (12%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ QL LG+GT VY+GR R G V LK ++
Sbjct 5 SQFQQLEKLGEGTYATVYKGRNRTTGQ------------------------LVALKEINL 40
Query 647 SHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--RER 703
+ SLM ++ H ++ ++ V + +V EY++ L ++ +
Sbjct 41 DSEEGTPSTAIREISLMKELKHENIVTLYDVIHTENKLNLVFEYMDK-DLKKFMDTNGNK 99
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
G + QL + + + ++H ++ +N+L+ G +KL+D G+
Sbjct 100 GALETKQVKWFMYQLLRGILFCHDNRVLHRDLKPQNLLINAKGQ-------LKLADFGLA 152
Query 764 LG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ V + + AP+ L G+ + ST++D W G + E+ S +
Sbjct 153 RAFGIPVNTFSNEVVTLWYRAPDVLL-GSRTYSTSIDIWSAGCIMAEMFTGRPLFPGSSN 211
Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
+ +H ++ E + P +++L + ++ R I+ + + L +L
Sbjct 212 DDQLQHIFKLMGTPNESTWPNISSLPNYRSNFQVYAPQDLRVIIPQIDNVALDLLLSLLQ 271
Query 880 VNPDSPASDPTVFHKRYLKKIR 901
+ P++ + + +
Sbjct 272 LKPENRITARQSLEHPWFAEYH 293
>sp|Q9HFW2|CLA4_EREGS Serine/threonine-protein kinase CLA4 OS=Eremothecium
gossypii (strain ATCC 10895 / CBS 109.51 / FGSC
9923 / NRRL Y-1056) OX=284811 GN=CLA4 PE=3 SV=1
Length=793
Score = 223 bits (567), Expect = 3e-59, Method: Composition-based stats.
Identities = 72/301 (24%), Positives = 119/301 (40%), Gaps = 40/301 (13%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT--------------NDGTGEMVAVKALKA 934
+ + I G+G G V L ND G+ VA+K +
Sbjct 490 FNTDPSPFFQMIEKAGQGASGSVYLAQRLKIPPYDENSGVSQHELNDNIGDKVAIKQMIL 549
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993
P+ + EI +++ H++I+ + + E L +VMEY+ GSL D +
Sbjct 550 SKQPR-KELIVNEILVMKDSQHKNIVNFLEAYL-KTEDDLWVVMEYMEGGSLTDVIENSI 607
Query 994 -------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
+ Q+ ++ C+G+ +LH +H IHRD+ + NVLLD VKI DFG
Sbjct 608 GSDASESPMTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTHGRVKITDFGFCA 667
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
+ + R +W APE +K+ ++ DVWS G+ E+L PP
Sbjct 668 KLTDKR---SKRATMVGTPYWMAPEVVKQREYDEKVDVWSLGIMTIEML-----EGEPPY 719
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
E + T +L P+ E+ + C + +R + E L+
Sbjct 720 LNEEPLKALYLIATNGT--------PKLKHPELLSLEIKRFLSVCLCVDVRYRASTEELL 771
Query 1167 P 1167
Sbjct 772 H 772
Score = 192 bits (488), Expect = 3e-49, Method: Composition-based stats.
Identities = 55/314 (18%), Positives = 103/314 (33%), Gaps = 31/314 (10%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L+ ++F+ + GQG +VY + D G E G
Sbjct 485 LAAVTFNTDPSPFFQMIEKAGQGASGSVYLAQRLKIPPYDENSGVSQHELNDNIGD---- 540
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGP 694
+V +K + S +M H ++ ++ + +V EY+E G
Sbjct 541 --KVAIKQMILSKQPRKELIVNEILVMKDSQHKNIVNFLEAYLKTEDDLWVVMEYMEGGS 598
Query 695 LDVWLRRE------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
L + + + ++ L +L +K+++H ++ N+LL G
Sbjct 599 LTDVIENSIGSDASESPMTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTHGR- 657
Query 749 EGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+K++D G R V W+APE + +D W G
Sbjct 658 ------VKITDFGFCAKLTDKRSKRATMVGTPYWMAPEVVKQ--REYDEKVDVWSLGIMT 709
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQH----RLPEPSCPQLATLTSQCLTYEPTQRPSFR 860
+E+ +GE P + P + + + PE ++ S CL + R S
Sbjct 710 IEML-EGEPPYLNEEPLKALYLIATNGTPKLKHPELLSLEIKRFLSVCLCVDVRYRASTE 768
Query 861 TILRDLTRLQPHNL 874
+L
Sbjct 769 ELLHHSFFETSCEP 782
>sp|A8X6H4|CMK1_CAEBR Calcium/calmodulin-dependent protein kinase
type 1 OS=Caenorhabditis briggsae OX=6238 GN=cmk-1 PE=3
SV=4
Length=356
Score = 211 bits (537), Expect = 3e-59, Method: Composition-based stats.
Identities = 64/265 (24%), Positives = 101/265 (38%), Gaps = 34/265 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G F KV L G++ AVK + + EI +LR L H +I++
Sbjct 28 LGTGAFSKVFLAESK---TDVGQLYAVKCIDKKALKGKEESLENEIKVLRKLRHNNIVQL 84
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
+++ + + LVME V G L D + + S +Q+ E ++++H +H
Sbjct 85 FETYDEK--QFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAVSFMHDNGVVH 142
Query 1022 RDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
RDL N+L D D + I DFGL+K G V + APE L++ +
Sbjct 143 RDLKPENLLYYNQDEDSKIMISDFGLSKTEDSG-----VMATACGTPGYVAPEVLQQKPY 197
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP- 1137
A DVWS GV Y LL + ++++ P
Sbjct 198 GKAVDVWSIGVIAYILLCGYPPF--------------YDESDANLFAQIIKGEYEFDAPY 243
Query 1138 -DKCPCEVYHLM--KNCWETEASFR 1159
D+ + C + R
Sbjct 244 WDQISDSAKDFISHLMCC--DPEMR 266
Score = 154 bits (390), Expect = 1e-39, Method: Composition-based stats.
Identities = 45/308 (15%), Positives = 91/308 (30%), Gaps = 35/308 (11%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+++ LG G + V+ D GQ +K +D
Sbjct 19 REKYDFRDVLGTGAFSKVFLA---------------------ESKTDVGQ--LYAVKCID 55
Query 646 PSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
++ ++ H ++ + +V E V G L + +G
Sbjct 56 KKALKGKEESLENEIKVLRKLRHNNIVQLFETYDEKQFVYLVMELVTGGELFDRI-VAKG 114
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ +Q+ A+S++ + +VH ++ N+L + I +SD G+
Sbjct 115 SYTEQDASNLIRQVLEAVSFMHDNGVVHRDLKPENLL----YYNQDEDSKIMISDFGLSK 170
Query 765 GALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
S ++APE L A+D W G I G P S +
Sbjct 171 TEDSGVMATACGTPGYVAPEVLQQ--KPYGKAVDVWSIGVIAY-ILLCGYPPFYDESDAN 227
Query 823 KEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
+ + P Q++ +++ P R + + T +
Sbjct 228 LFAQIIKGEYEFDAPYWDQISDSAKDFISHLMCCDPEMRFTCQSALEHPWISGNTAYTHD 287
Query 882 PDSPASDP 889
+
Sbjct 288 IHRTVAVH 295
>sp|O14965|AURKA_HUMAN Aurora kinase A OS=Homo sapiens OX=9606
GN=AURKA PE=1 SV=3
Length=403
Score = 213 bits (541), Expect = 3e-59, Method: Composition-based stats.
Identities = 63/290 (22%), Positives = 110/290 (38%), Gaps = 30/290 (10%)
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQ 939
+ S + + R LG+G FG V L + ++A+K L KA
Sbjct 117 KQKNEESKKRQWALEDFEIGRPLGKGKFGNVYL----AREKQSKFILALKVLFKAQLEKA 172
Query 940 HRS-GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGL 997
++E++I L H +I++ G D + L++EY PLG++ L +
Sbjct 173 GVEHQLRREVEIQSHLRHPNILRLYGYFHDAT--RVYLILEYAPLGTVYRELQKLSKFDE 230
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
+ + ++ ++Y H++ IHRD+ N+LL + +KI DFG + P
Sbjct 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSR----- 285
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
R + + PE ++ D+WS GV YE L ++
Sbjct 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA-------------- 331
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
T + + R E PD L+ + S RP ++
Sbjct 332 -NTYQETYKRISRVE-FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLE 379
Score = 186 bits (471), Expect = 7e-50, Method: Composition-based stats.
Identities = 57/301 (19%), Positives = 109/301 (36%), Gaps = 41/301 (14%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
++ LG+G NVY R++ + + LKVL
Sbjct 131 EDFEIGRPLGKGKFGNVYLA------------------------REKQSKFILALKVLFK 166
Query 647 SHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ + + + S + H ++ ++G ++ EY G + L++
Sbjct 167 AQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKL- 225
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+LA+ALSY +K ++H ++ N+LL G++ +K++D G
Sbjct 226 SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLL-------GSAGELKIADFGWS 278
Query 764 LGALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ A S R + +L PE + G + +D W G E G+ P ++ +
Sbjct 279 VHAPSSRRTTLCGTLDYLPPEMIEGRMH--DEKVDLWSLGVLCYEFLV-GKPPFEANTYQ 335
Query 822 EKEH-FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880
E + + P+ L S+ L + P+QRP R +L +
Sbjct 336 ETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQN 395
Query 881 N 881
Sbjct 396 K 396
>sp|Q54SJ5|MYLKC_DICDI Probable myosin light chain kinase DDB_G0282429
OS=Dictyostelium discoideum OX=44689 GN=DDB_G0282429
PE=3 SV=1
Length=312
Score = 209 bits (533), Expect = 3e-59, Method: Composition-based stats.
Identities = 70/271 (26%), Positives = 106/271 (39%), Gaps = 32/271 (12%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHI 959
++G G F V + T+ TG VA+K++ +EI+I++ + H +I
Sbjct 42 NEIGRGAFSIVR----EATSRATGTKVAIKSINTRFIKN--KLLMREIEIMKKVGDHPNI 95
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018
+K E K L LV+E V G L D + R +QI + +LHA
Sbjct 96 LKLYEVYE--TTKHLHLVLELVTGGELFDKIVQRGEYSEQDASKIVRQIVSAVGHLHANG 153
Query 1019 YIHRDLAARNVLL--DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
HRDL +N+L + +++ DFGL+K +G E + APE L+
Sbjct 154 IAHRDLKPQNLLCAGEEGDDIRVADFGLSKIFGDGDYL----ETCCGSPEYVAPEVLECK 209
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER-GERLP 1135
+ A D+WS GV Y LLT C L E + P
Sbjct 210 PYDKACDLWSVGVITYVLLTGCFPF---------------WDKNNAVLYEKIRNVDYGWP 254
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ E L+ + E R TFE +
Sbjct 255 EGLEVSNEAKDLVSHLIEKNPEKRFTFEQCL 285
Score = 155 bits (392), Expect = 2e-40, Method: Composition-based stats.
Identities = 49/287 (17%), Positives = 92/287 (32%), Gaps = 41/287 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ +G+G + V E R G +V +K ++ +
Sbjct 37 NYILGNEIGRGAFSIVREATSRATG------------------------TKVAIKSIN-T 71
Query 648 HHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
+M +V H ++ ++ V +V E V G L + +RG
Sbjct 72 RFIKNKLLMREIEIMKKVGDHPNILKLYEVYETTKHLHLVLELVTGGELFDKI-VQRGEY 130
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-- 764
+ +Q+ SA+ +L + H ++ +N+L A + I+++D G+
Sbjct 131 SEQDASKIVRQIVSAVGHLHANGIAHRDLKPQNLLCAGEEGDD-----IRVADFGLSKIF 185
Query 765 -GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS-- 821
E ++APE L A D W G + G P ++ +
Sbjct 186 GDGDYLETCCGSPEYVAPEVLE--CKPYDKACDLWSVGVITY-VLLTGCFPFWDKNNAVL 242
Query 822 -EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
EK + L S + P +R +F L
Sbjct 243 YEKIRNVDYGWPEGLEVSNEAKDLVSHLIEKNPEKRFTFEQCLIHPW 289
>sp|Q8VCT9|TESK2_MOUSE Dual specificity testis-specific protein
kinase 2 OS=Mus musculus OX=10090 GN=Tesk2 PE=1 SV=1
Length=570
Score = 218 bits (554), Expect = 3e-59, Method: Composition-based stats.
Identities = 71/285 (25%), Positives = 124/285 (44%), Gaps = 33/285 (12%)
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+G G F +V + + +G+++A+K + +R+ +E+ ++ L H
Sbjct 59 FTREKIGSGFFSEV----FKVRHRASGQVMALKM---NTLSSNRANLLKEMQLMNRLSHP 111
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHA 1016
+I+++ G C QG+ L + EY+ G+L L + + A I G++YLH
Sbjct 112 NILRFMGVCVHQGQ--LHALTEYINSGNLEQLLDSDLYLPWTVRVKLAYDIAVGLSYLHF 169
Query 1017 QHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ HRDL ++N L+ D + DFGLA+ +P+ R + FW APE L
Sbjct 170 KGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDA-SIGREKLAVVGSPFWMAPEVL 228
Query 1074 KEYKFYYASDVWSFGVTLYELLTH--CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
++ + +DV+S+G+ L E++ D P T+ L A M
Sbjct 229 RDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVG---------- 278
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176
CP + L NC + RP+FE + LK + +
Sbjct 279 -------DCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLKEIMSRL 316
Score = 192 bits (489), Expect = 1e-50, Method: Composition-based stats.
Identities = 65/314 (21%), Positives = 116/314 (37%), Gaps = 40/314 (13%)
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
++ R S + +F R+ + +G G + V++ R R
Sbjct 33 VQVGRVSSSSYRAIISAFSRLTSLDDFTREKIGSGFFSEVFKVRHRA------------- 79
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
GQ + + + L + ++ + LM+++SH ++ GVCV +
Sbjct 80 ---------SGQVMALKMNTLSSNRANL----LKEMQLMNRLSHPNILRFMGVCVHQGQL 126
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+TEY+ G L+ L ++P ++ +A +A LSYL K + H ++ +N L+
Sbjct 127 HALTEYINSGNLEQLL-DSDLYLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIK 185
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDK 797
R + ++D G+ V W+APE L + D
Sbjct 186 R----DENGYSAVVADFGLAEKIPDASIGREKLAVVGSPFWMAPEVLRD--EPYNEKADV 239
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQR 856
+ +G L EI +A +E + CP LT C +P R
Sbjct 240 FSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVGDCPSDFLQLTFNCCNMDPKLR 299
Query 857 PSFRTILRDLTRLQ 870
PSF I + L +
Sbjct 300 PSFEEIGKTLKEIM 313
>sp|Q60855|RIPK1_MOUSE Receptor-interacting serine/threonine-protein
kinase 1 OS=Mus musculus OX=10090 GN=Ripk1 PE=1 SV=1
Length=656
Score = 219 bits (559), Expect = 3e-59, Method: Composition-based stats.
Identities = 72/287 (25%), Positives = 120/287 (42%), Gaps = 33/287 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG-PQHRSGWKQEIDILRTLYHEHII 960
DL G FGKVSL + V +K + ++ +E ++ L H ++
Sbjct 22 DLDSGGFGKVSLCYHRSHG-----FVILKKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVV 76
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHY 1019
K G ++G + LVMEY+ G+L L + L+ + EGM YLH +
Sbjct 77 KLLGIIIEEG--NYSLVMEYMEKGNLMHVLKTQIDVPLSLKGRIIVEAIEGMCYLHDKGV 134
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLA-----------KAVPEGHEYYRVREDGDSPVFWY 1068
IH+DL N+L+D D +KI D G+A K + +++ +++
Sbjct 135 IHKDLKPENILVDRDFHIKIADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYM 194
Query 1069 APECLKE--YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
APE L + K SDV+SFG+ L+ + + ++ +I I G +
Sbjct 195 APEHLNDINAKPTEKSDVYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNRPNVE--- 251
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
+ CP E+ LM+ CW+ RPTF + + +
Sbjct 252 --------EILEYCPREIISLMERCWQAIPEDRPTFLGIEEEFRPFY 290
Score = 187 bits (475), Expect = 2e-48, Method: Composition-based stats.
Identities = 58/326 (18%), Positives = 117/326 (36%), Gaps = 60/326 (18%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
L ++ ++ + + L G V R G
Sbjct 6 SLDNIKMASSDLLEKTDLDSGGFGKVSLCYHRSHGF------------------------ 41
Query 638 RVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V+LK + P+ + E +M ++ H+ + + G+ + +V EY+E G L
Sbjct 42 -VILKKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVVKLLGIIIEEGNYSLVMEYMEKGNL 100
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
L+ + VP++ K + + + YL +K ++H ++ NIL+ R I
Sbjct 101 MHVLKTQ-IDVPLSLKGRIIVEAIEGMCYLHDKGVIHKDLKPENILVDR-------DFHI 152
Query 756 KLSDPGVG------------------LGALSREERVERIPWLAPECLPGGANSLSTAMDK 797
K++D GV + + +++ + ++APE L + D
Sbjct 153 KIADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMAPEHLNDINAKPTEKSDV 212
Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP------EPSCPQLATLTSQCLTY 851
+ FG L I F + P ++ +E+ + P E ++ +L +C
Sbjct 213 YSFGIVLWAI-FAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPREIISLMERCWQA 271
Query 852 EPTQRPSFRTILRDLTRLQPHNLADV 877
P RP+F I + + +
Sbjct 272 IPEDRPTFLGIEEEFRPFYLSHFEEY 297
>sp|Q2QYM3|CIPKE_ORYSJ CBL-interacting protein kinase 14 OS=Oryza
sativa subsp. japonica OX=39947 GN=CIPK14 PE=2 SV=1
Length=439
Score = 214 bits (544), Expect = 3e-59, Method: Composition-based stats.
Identities = 61/267 (23%), Positives = 113/267 (42%), Gaps = 27/267 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960
LG+G FGKV N + + VA+K + + ++EI +R + H++I+
Sbjct 18 LGKGTFGKVHY----ARNLESNQSVAIKMMDKQQVLKVGLSEQIRREITTMRLVAHKNIV 73
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ + + + VMEYV G L + + R + + QQ+ + Y H++
Sbjct 74 QLHEVMATRNK--IYFVMEYVKGGELFEKVAKRGKLTEVVAHKYFQQLISAVDYCHSRGV 131
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
HRDL N+LLD + +K+ DFGL+ + + +P + APE + + +
Sbjct 132 YHRDLKPENLLLDENENLKVSDFGLSALSESKRQDGLLHTTCGTPA-YVAPEVISKIGYD 190
Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SD+WS GV L+ L+ Q P ++ + ++ GE P
Sbjct 191 GAKSDIWSCGVILFVLVAGYLPFQGP---------------NLMEMYRKIQHGE-FRCPG 234
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENL 1165
++ L+ + S R + + +
Sbjct 235 WFSRKLQKLLYKIMDPNPSTRISIQKI 261
Score = 181 bits (458), Expect = 7e-48, Method: Composition-based stats.
Identities = 56/296 (19%), Positives = 100/296 (34%), Gaps = 44/296 (15%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
++ + LG+GT V+ R V +K
Sbjct 6 KILMERYELGRLLGKGTFGKVHYARNLESNQS------------------------VAIK 41
Query 643 VLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
++D ++ + M V+H ++ +H V + V EYV+ G L +
Sbjct 42 MMDKQQVLKVGLSEQIRREITTMRLVAHKNIVQLHEVMATRNKIYFVMEYVKGGELFEKV 101
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+RG + QQL SA+ Y ++ + H ++ N+LL + +K+SD
Sbjct 102 -AKRGKLTEVVAHKYFQQLISAVDYCHSRGVYHRDLKPENLLLDE-------NENLKVSD 153
Query 760 PGVGLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
G+ + S+ ++APE + D W G L + G
Sbjct 154 FGLSALSESKRQDGLLHTTCGTPAYVAPEVISKIGYD-GAKSDIWSCGVIL-FVLVAGYL 211
Query 814 PLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
P Q + E + R P +L L + + P+ R S + I
Sbjct 212 PFQGPNLMEMYRKIQHGEFRCPGWFSRKLQKLLYKIMDPNPSTRISIQKIKESTWF 267
>sp|Q924X7|STK33_MOUSE Serine/threonine-protein kinase 33 OS=Mus
musculus OX=10090 GN=Stk33 PE=1 SV=2
Length=491
Score = 215 bits (548), Expect = 3e-59, Method: Composition-based stats.
Identities = 79/380 (21%), Positives = 150/380 (39%), Gaps = 45/380 (12%)
Query 804 LLEICFDGEAPLQSRSPSEK-----EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPS 858
LL +C G++P+ S+ F+ Q R E + + ++L + S
Sbjct 23 LLCVCPAGKSPVLVVEMSQTSSIGSTEFFASQERKKERNTSRESSL----------KDLS 72
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918
RT + + ++V D + + R LG+G FG V ++
Sbjct 73 IRTSNVERKPQAQWSRSNVTVGKIPHIRMDDGAGIEEFYTFGRILGQGSFGMV----FEA 128
Query 919 TNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLV 977
+ TG A+K + + G ++E+ IL+T+ H+HII + E + + LV
Sbjct 129 IDKETGAKWAIKKVNKEKAGSSAMKLLEREVSILKTVNHQHIIHLEQVFESP--QKMYLV 186
Query 978 MEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN--- 1033
ME G L+ + R + L Q + +AYLH + +HRDL N+++ +
Sbjct 187 MELCEDGELKAVMDQRGHFSENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFI 246
Query 1034 ------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
+ +K+ DFGL+ ++ +P+ + APE + + + D+WS
Sbjct 247 DDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPI-YMAPEVINAHDYSQQCDIWSI 305
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
GV ++ LL +A + + L + E P + +
Sbjct 306 GVIMFILLCGEPPF------------LANSEEKLYELIKKGELRFENPVWESVSDSAKNT 353
Query 1148 MKNCWETEASFRPTFENLIP 1167
+K + + + R T + L+
Sbjct 354 LKQLMKVDPAHRITAKELLD 373
Score = 183 bits (465), Expect = 3e-48, Method: Composition-based stats.
Identities = 58/291 (20%), Positives = 111/291 (38%), Gaps = 39/291 (13%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
T LGQG+ V+E + G+ + ++ +K+L+
Sbjct 112 TFGRILGQGSFGMVFEAIDKETGAKWAIKKVNKEKAGSS-----------AMKLLE---- 156
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
S++ V+H H+ + V + +V E E G L + +RGH
Sbjct 157 -------REVSILKTVNHQHIIHLEQVFESPQKMYLVMELCEDGELKAVM-DQRGHFSEN 208
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG--TSPFIKLSDPGV----- 762
++ Q LASA++YL NK++VH ++ NI++ + + + IK++D G+
Sbjct 209 ETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKH 268
Query 763 -GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ ++APE + A+ S D W G + I GE P + S
Sbjct 269 GSRSEGMMQTTCGTPIYMAPEVI--NAHDYSQQCDIWSIGVIM-FILLCGEPPFLANSEE 325
Query 822 EKEHFYQRQ-----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ ++ + + E Q + +P R + + +L +
Sbjct 326 KLYELIKKGELRFENPVWESVSDSAKNTLKQLMKVDPAHRITAKELLDNQW 376
>sp|P34892|KIN16_CAEEL Receptor-like tyrosine-protein kinase kin-16
OS=Caenorhabditis elegans OX=6239 GN=kin-16 PE=2 SV=1
Length=495
Score = 215 bits (548), Expect = 3e-59, Method: Composition-based stats.
Identities = 88/323 (27%), Positives = 126/323 (39%), Gaps = 70/323 (22%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEM------VAVKALKADCGPQHRSGWKQEIDILRTL-Y 955
LG G+FG V + E VAVK+ S E+ ++ ++
Sbjct 146 LGSGNFGVVRKGILKMASPKNEEEKKMRLTVAVKSAANCYDISQTSMLAAELRLMCSIGR 205
Query 956 HEHIIKYKGCCEDQGEK-SLQLVMEYVPLGSLRDYLPRH--------------------- 993
+++ G + K L +V EY+ G +R YL H
Sbjct 206 FPNVLALVGAVTSELRKGRLLIVTEYIDCGDIRKYLIDHRNVFQDHLIEDKTEPDSYLTP 265
Query 994 --------------------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027
S+ + LL F QI GM YL + +HRDLA R
Sbjct 266 ISAKRKNYVFKNTDENSDYVIKESLDSLTTSDLLSFGLQIANGMQYLASIPMVHRDLALR 325
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYY-RVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
NVLL ++ ++I DFG+A+ Y + +D PV W +PE KF SDVWS
Sbjct 326 NVLLKKNKTIRIADFGMARTHENKSYYIPQKTKDAPVPVRWMSPEAFDTMKFTEKSDVWS 385
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
FG+ LYE+ T L + + R+ E + G R P+P C E+Y
Sbjct 386 FGICLYEIFT--------------LGQLPYPDVPSERIYEYMHSGRRCPQPQHCHVELYD 431
Query 1147 LMKNCWETEASFRPTFENLIPIL 1169
LMK CW + RP F N +
Sbjct 432 LMKLCWHEKPELRPNFSNCVEYF 454
Score = 177 bits (449), Expect = 3e-46, Method: Composition-based stats.
Identities = 61/355 (17%), Positives = 112/355 (32%), Gaps = 83/355 (23%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L + + + + S LG G V +G L++ + EE KM
Sbjct 127 LPYKKQYEIASENLENKSILGSGNFGVVRKGILKMASPKNEEEKKMR------------- 173
Query 636 ELRVVLKVLDPSHHDIALAFYE-TASLMSQV-SHTHLAFVHGVCV---RGPENIMVTEYV 690
L V +K + + LM + ++ + G R ++VTEY+
Sbjct 174 -LTVAVKSAANCYDISQTSMLAAELRLMCSIGRFPNVLALVGAVTSELRKGRLLIVTEYI 232
Query 691 EHGPLDVWLRRERG---------------------------------------------H 705
+ G + +L R
Sbjct 233 DCGDIRKYLIDHRNVFQDHLIEDKTEPDSYLTPISAKRKNYVFKNTDENSDYVIKESLDS 292
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+ + + Q+A+ + YL + +VH ++ RN+LL + + I+++D G+
Sbjct 293 LTTSDLLSFGLQIANGMQYLASIPMVHRDLALRNVLLKK-------NKTIRIADFGMART 345
Query 766 ALSREERV--------ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
++ + + W++PE + D W FG L EI G+ P
Sbjct 346 HENKSYYIPQKTKDAPVPVRWMSPEAFDTM--KFTEKSDVWSFGICLYEIFTLGQLPYPD 403
Query 818 RSPSEKEHFYQRQHRLPEPSCPQ--LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ R P+P L L C +P RP+F +
Sbjct 404 VPSERIYEYMHSGRRCPQPQHCHVELYDLMKLCWHEKPELRPNFSNCVEYFIGHM 458
>sp|P25848|PHY1_CERPU Light-sensor Protein kinase OS=Ceratodon
purpureus OX=3225 GN=PHY1 PE=3 SV=3
Length=1307
Score = 227 bits (578), Expect = 4e-59, Method: Composition-based stats.
Identities = 79/384 (21%), Positives = 135/384 (35%), Gaps = 69/384 (18%)
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
+ LT + L+ + + + + + + + ++++
Sbjct 948 IYDLTEKTLSSDQNDLAIYLLQRLKRAKPILPSFSSRPSWWNFYDDWSFSEKFFQWIQIT 1007
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG G V + G VA K ++ +K+E++IL L H +I
Sbjct 1008 GSLGSGSSATVEKAVWL------GTPVAKKTFYG----RNNEDFKREVEILAELCHPNIT 1057
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----------SIGLAQLLLFAQQICEG 1010
C + ++ME + G L + R + +++ Q EG
Sbjct 1058 SM--FCSPLYRRKCSIIMELMD-GDLLALMQRRLDRNEDHDSPPFSILEVVDIILQTSEG 1114
Query 1011 MAYLHAQHYIHRDLAARNVLLDN---------DRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
M YLH + IHRDL + N+L+ + VK+ DFGL+K + Y +
Sbjct 1115 MNYLHEKGIIHRDLKSMNILVKSVKVTKSEIGYVHVKVADFGLSKT-KDSSTRYSNQTWN 1173
Query 1062 DSPVFWYAPECLKEY---------------KFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
W APE + K+ SDV+SFG+ YE+LT
Sbjct 1174 RGTNRWMAPEVINLGYESTEGEISFDGKVPKYPLKSDVYSFGMVCYEVLTGDVPFPE--- 1230
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ + ++ G R P CP E+ L+ +CW + RP+F +
Sbjct 1231 -----------EKNPNNVKRMVLEGVRPDLPAHCPIELKALITDCWNQDPLKRPSFAVIC 1279
Query 1167 PILKTVH-------EKYQGQAPSV 1183
LK + YQ PS
Sbjct 1280 QKLKYLKYLLMTGFSSYQDSYPST 1303
Score = 174 bits (440), Expect = 1e-42, Method: Composition-based stats.
Identities = 58/370 (16%), Positives = 114/370 (31%), Gaps = 81/370 (22%)
Query 562 IIMRGARASPRTLNLS----------QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
++ R RA P + S SF + I LG G+ V +
Sbjct 967 LLQRLKRAKPILPSFSSRPSWWNFYDDWSFSEKFFQWIQITGSLGSGSSATVEKAVWLG- 1025
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
V K + F +++++ H ++
Sbjct 1026 -------------------------TPVAKKTF---YGRNNEDFKREVEILAELCHPNIT 1057
Query 672 FVHGVCVRGPENI-----MVTEYVEHGPLDVWLRRE--------RGHVPMAWKMVVAQQL 718
+ C ++ E ++ G L ++R + + + Q
Sbjct 1058 SM--FC---SPLYRRKCSIIMELMD-GDLLALMQRRLDRNEDHDSPPFSILEVVDIILQT 1111
Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP--FIKLSDPGVGLGALSREERV--- 773
+ ++YL K ++H ++ NIL+ + + + +K++D G+ S
Sbjct 1112 SEGMNYLHEKGIIHRDLKSMNILVKSVKVTKSEIGYVHVKVADFGLSKTKDSSTRYSNQT 1171
Query 774 ---ERIPWLAPECLPGGAN-------------SLSTAMDKWGFGATLLEICFDGEAPLQS 817
W+APE + G D + FG E+ +
Sbjct 1172 WNRGTNRWMAPEVINLGYESTEGEISFDGKVPKYPLKSDVYSFGMVCYEVLTGDVPFPEE 1231
Query 818 RSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
++P+ + R LP +L L + C +P +RPSF I + L L+ +
Sbjct 1232 KNPNNVKRMVLEGVRPDLPAHCPIELKALITDCWNQDPLKRPSFAVICQKLKYLKYLLMT 1291
Query 876 DVLTVNPDSP 885
+ P
Sbjct 1292 GFSSYQDSYP 1301
>sp|Q54QI2|Y9877_DICDI Serine/threonine-protein kinase DDB_G0283821
OS=Dictyostelium discoideum OX=44689 GN=DDB_G0283821 PE=3
SV=1
Length=941
Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats.
Identities = 74/284 (26%), Positives = 121/284 (43%), Gaps = 33/284 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G FGKV + N TG+ A+K + K + QEI +L+TL H +I+K
Sbjct 19 VGKGAFGKV----FKALNAETGDFCAIKQIEKTIISEKQLPSIIQEIKLLQTLQHPNIVK 74
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ E + L +E++ GSL R+ L + Q+ +G+AYLH + I
Sbjct 75 FIESYE--TSRYLYFALEFIEGGSLAKIAKRYGCFQEPLLSRYFSQVLKGLAYLHEKGVI 132
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF-- 1078
HRD+ + N+L+ + ++K+ DFG + FW APE ++
Sbjct 133 HRDIKSDNILITKEGVIKLADFGSCTY-----SAIDRKLTVVGTPFWMAPEVIQMDMNAR 187
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
A D+WS G TL E+LT +PP L + +
Sbjct 188 STACDIWSLGCTLLEMLTG-----NPPYWDLGTMPAMFAMVNNPHPPIPNNI-------- 234
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIP---ILKTVHEKYQGQ 1179
++ H + C+ + + RPT L+ I + +HE Q Q
Sbjct 235 --SADLKHFLLACFVRDINKRPTASQLLEHPWIKQHIHEPSQSQ 276
Score = 187 bits (474), Expect = 4e-47, Method: Composition-based stats.
Identities = 59/328 (18%), Positives = 101/328 (31%), Gaps = 39/328 (12%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ +G+G V++ G +K +
Sbjct 9 SFSKYQIGEAVGKGAFGKVFKALNAETGDFC------------------------AIKQI 44
Query 645 DPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+ + + + L+ + H ++ E++E G L + +
Sbjct 45 EKTIISEKQLPSIIQEIKLLQTLQHPNIVKFIESYETSRYLYFALEFIEGGSLAK-IAKR 103
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
G Q+ L+YL K ++H ++ NIL+ + G+ IKL+D G
Sbjct 104 YGCFQEPLLSRYFSQVLKGLAYLHEKGVIHRDIKSDNILITKEGV-------IKLADFGS 156
Query 763 GL-GALSRE-ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR-- 818
A+ R+ V W+APE + N+ STA D W G TLLE+ G P
Sbjct 157 CTYSAIDRKLTVVGTPFWMAPEVIQMDMNARSTACDIWSLGCTLLEML-TGNPPYWDLGT 215
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
P+ +P L C + +RP+ +L Q +
Sbjct 216 MPAMFAMVNNPHPPIPNNISADLKHFLLACFVRDINKRPTASQLLEHPWIKQHIHEPSQS 275
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906
S I EG
Sbjct 276 QPASSPEPSRIKSSGSGSKLSINTYAEG 303
>sp|Q8RXC8|RBK2_ARATH Receptor-like cytosolic serine/threonine-protein
kinase RBK2 OS=Arabidopsis thaliana OX=3702 GN=RBK2
PE=1 SV=1
Length=460
Score = 214 bits (545), Expect = 4e-59, Method: Composition-based stats.
Identities = 70/336 (21%), Positives = 133/336 (40%), Gaps = 23/336 (7%)
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD-- 902
+ ++ P + I ++ + N + + + +
Sbjct 86 MKRLSSFPPLSGAAPPIIKQNKSADPNMNGMVLHDIYDFQSSLQNFSISDIEIATDNFSP 145
Query 903 ---LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959
+G G + V G+++AVK L + + + E+ I+ + H +
Sbjct 146 ENIIGRGGYADVYQGILPE-----GKLIAVKRLTKGTPDEQTAEFLSELGIIAHVDHPNT 200
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHA 1016
K+ GCC + G + LV PLGSL L ++ + ++ A +G+ YLH
Sbjct 201 AKFIGCCIEGG---MHLVFRLSPLGSLGSLLHGPSKYKLTWSRRYNVALGTADGLVYLHE 257
Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ IHRD+ A N+LL D +I DFGLAK +P+ ++ V + + ++APE
Sbjct 258 GCQRRIIHRDIKADNILLTEDFQPQICDFGLAKWLPKQLTHHNVSK-FEGTFGYFAPEYF 316
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+DV++FGV L EL+T + L+ A+ + + EL++
Sbjct 317 MHGIVDEKTDVFAFGVLLLELITGHPALD---ESQQSLVLWAKPLLERKAIKELVDPSLG 373
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+ + C + + RP ++ +L
Sbjct 374 DEYNREELIRLTSTASLCIDQSSLLRPRMSQVVELL 409
Score = 174 bits (441), Expect = 2e-45, Method: Composition-based stats.
Identities = 50/297 (17%), Positives = 93/297 (31%), Gaps = 50/297 (17%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
N +++ +L +S + + + +G+G +VY+G L
Sbjct 112 NMNGMVLHDIYDFQSSLQNFSISDIEIATDNFSPENIIGRGGYADVYQGILPEGK----- 166
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGV 676
+ +K L D F +++ V H + A G
Sbjct 167 --------------------LIAVKRLTKGTPDEQTAEFLSELGIIAHVDHPNTAKFIGC 206
Query 677 CVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVH 732
C+ G +V G L L + + + VA A L YL + ++H
Sbjct 207 CIEGG-MHLVFRLSPLGSLGSLLHGPSKYKLTWSRRYNVALGTADGLVYLHEGCQRRIIH 265
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG------LGALSREERVERIPWLAPECLPG 786
++ NILL + + D G+ L + + + APE
Sbjct 266 RDIKADNILLTEDFQPQ-------ICDFGLAKWLPKQLTHHNVSKFEGTFGYFAPEYFMH 318
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT 843
G + D + FG LLE+ + S++ + L + +L
Sbjct 319 GI--VDEKTDVFAFGVLLLELITG----HPALDESQQSLVLWAKPLLERKAIKELVD 369
>sp|Q9SYQ8|CLV1_ARATH Receptor protein kinase CLAVATA1 OS=Arabidopsis
thaliana OX=3702 GN=CLV1 PE=1 SV=3
Length=980
Score = 224 bits (572), Expect = 4e-59, Method: Composition-based stats.
Identities = 75/327 (23%), Positives = 126/327 (39%), Gaps = 29/327 (9%)
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920
++ + + + + + LK+ +G+G G V +
Sbjct 656 SVAIRQMNKKKNQKSLAWKLTAFQKLDFKSEDVLECLKEENIIGKGGAGIVYRG-----S 710
Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
VA+K L + G+ EI L + H HI++ G ++ L+ EY
Sbjct 711 MPNNVDVAIKRLVGRGTGRSDHGFTAEIQTLGRIRHRHIVRLLGYVANKDTN--LLLYEY 768
Query 981 VPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDND 1034
+P GSL + L + A + +G+ YLH +HRD+ + N+LLD+D
Sbjct 769 MPNGSLGELLHGSKGGHLQWETRHRVAVEAAKGLCYLHHDCSPLILHRDVKSNNILLDSD 828
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
+ DFGLAK + +G + S + APE K SDV+SFGV L EL
Sbjct 829 FEAHVADFGLAKFLVDGAASECMSSIAGS-YGYIAPEYAYTLKVDEKSDVYSFGVVLLEL 887
Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLR----------LTELLERGERLPRPDKCPCEV 1144
+ P +F E + I + + +++ P V
Sbjct 888 IAGK----KPVGEFGEGVDIVRWVRNTEEEITQPSDAAIVVAIVDPRLTG-YPLTSVIHV 942
Query 1145 YHLMKNCWETEASFRPTFENLIPILKT 1171
+ + C E EA+ RPT ++ +L
Sbjct 943 FKIAMMCVEEEAAARPTMREVVHMLTN 969
Score = 185 bits (470), Expect = 1e-46, Method: Composition-based stats.
Identities = 58/323 (18%), Positives = 104/323 (32%), Gaps = 67/323 (21%)
Query 576 LSQLSFHRVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
+L F D E + + + +G+G VY G
Sbjct 678 FQKLDFKSEDVLECLKEENIIGKGGAGIVYRG-------------------------SMP 712
Query 635 QELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ V +K L F + ++ H H+ + G N+++ EY+ +G
Sbjct 713 NNVDVAIKRLVGRGTGRSDHGFTAEIQTLGRIRHRHIVRLLGYVANKDTNLLLYEYMPNG 772
Query 694 PLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAE 749
L L + GH+ + VA + A L YL + ++H +V NILL A
Sbjct 773 SLGELLHGSKGGHLQWETRHRVAVEAAKGLCYLHHDCSPLILHRDVKSNNILLDSDFEAH 832
Query 750 GTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
++D G+ + ++APE + D + FG
Sbjct 833 -------VADFGLAKFLVDGAASECMSSIAGSYGYIAPEYA--YTLKVDEKSDVYSFGVV 883
Query 804 LLEICFDGEA---------PLQSRSPSEKE------------HFYQRQHRLPEPSCPQLA 842
LLE+ + ++ +E+E R P S +
Sbjct 884 LLELIAGKKPVGEFGEGVDIVRWVRNTEEEITQPSDAAIVVAIVDPRLTGYPLTSVIHVF 943
Query 843 TLTSQCLTYEPTQRPSFRTILRD 865
+ C+ E RP+ R ++
Sbjct 944 KIAMMCVEEEAAARPTMREVVHM 966
>sp|Q9TXJ0|CMK1_CAEEL Calcium/calmodulin-dependent protein kinase
type 1 OS=Caenorhabditis elegans OX=6239 GN=cmk-1 PE=1 SV=1
Length=348
Score = 211 bits (536), Expect = 4e-59, Method: Composition-based stats.
Identities = 65/265 (25%), Positives = 100/265 (38%), Gaps = 34/265 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G F KV L G+M AVK + + EI +LR L H +I++
Sbjct 28 LGTGAFSKVFLAESK---SDAGQMYAVKCIDKKALKGKEESLENEIKVLRKLRHNNIVQL 84
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
+++ + + LVME V G L D + + S +Q+ E + ++H +H
Sbjct 85 FDTYDEK--QFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAVGFMHDNGVVH 142
Query 1022 RDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
RDL N+L D D + I DFGL+K G V + APE L++ +
Sbjct 143 RDLKPENLLYYNQDEDSKIMISDFGLSKTEDSG-----VMATACGTPGYVAPEVLQQKPY 197
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP- 1137
A DVWS GV Y LL + ++++ P
Sbjct 198 GKAVDVWSIGVIAYILLCGYPPF--------------YDESDANLFAQIIKGEYEFDAPY 243
Query 1138 -DKCPCEVYHLM--KNCWETEASFR 1159
D+ + C + R
Sbjct 244 WDQISDSAKDFITHLMCC--DPEAR 266
Score = 154 bits (390), Expect = 1e-39, Method: Composition-based stats.
Identities = 43/308 (14%), Positives = 90/308 (29%), Gaps = 35/308 (11%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+++ LG G + V+ + + +K +D
Sbjct 19 REKYDFRDVLGTGAFSKVFLAESKSDAGQMY-----------------------AVKCID 55
Query 646 PSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
++ ++ H ++ + +V E V G L + +G
Sbjct 56 KKALKGKEESLENEIKVLRKLRHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRI-VAKG 114
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ +Q+ A+ ++ + +VH ++ N+L + I +SD G+
Sbjct 115 SYTEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLL----YYNQDEDSKIMISDFGLSK 170
Query 765 GALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
S ++APE L A+D W G I G P S +
Sbjct 171 TEDSGVMATACGTPGYVAPEVLQQ--KPYGKAVDVWSIGVIAY-ILLCGYPPFYDESDAN 227
Query 823 KEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
+ + P Q++ +T+ P R +D + T +
Sbjct 228 LFAQIIKGEYEFDAPYWDQISDSAKDFITHLMCCDPEARFTCQDALSHPWISGNTAYTHD 287
Query 882 PDSPASDP 889
+
Sbjct 288 IHGTVAVH 295
>sp|Q9LUL4|SRF7_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 7 OS=Arabidopsis
thaliana OX=3702 GN=SRF7 PE=1 SV=1
Length=717
Score = 221 bits (562), Expect = 4e-59, Method: Composition-based stats.
Identities = 80/344 (23%), Positives = 139/344 (40%), Gaps = 25/344 (7%)
Query 834 PEPSCPQLATLTSQCLTYEPTQRP--SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV 891
P +L T S L P++R + A V+ N ++
Sbjct 354 PLVETKKLDTSLSMNLRPPPSERHKSFDDDDSTMRKPIVAKKAAVVVPSNVNTYTVSDLQ 413
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI-DI 950
LGEG FG+V ++ G+++AVK + + P + EI
Sbjct 414 VATNSFSVDNLLGEGTFGRVYRAQFE-----DGKVLAVKKIDSSALPTDTADDFTEIVSK 468
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQ 1005
+ L HE++ K G C + G+ +V E+ GSL D+L + + A
Sbjct 469 IAHLDHENVTKLDGYCSEHGQH--LVVYEFHRNGSLHDFLHLAEEESKPLIWNPRVKIAL 526
Query 1006 QICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062
+ YLH + +H+++ + N+LLD++ + D GLA +P +E ++G
Sbjct 527 GTARALEYLHEVCSPSIVHKNIKSANILLDSELNPHLSDSGLASFLPTANELLNQNDEG- 585
Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQM-T 1120
+ APE ++ SDV+SFGV + ELLT S ++ L+ A Q+
Sbjct 586 ----YSAPETSMSGQYSLKSDVYSFGVVMLELLTGRKPFDSTRSRSEQSLVRWATPQLHD 641
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ L ++++ + P K ++ C + E FRP
Sbjct 642 IDALGKMVDPALKGLYPVKSLSRFADVIALCVQPEPEFRPPMSE 685
Score = 184 bits (468), Expect = 4e-47, Method: Composition-based stats.
Identities = 71/325 (22%), Positives = 118/325 (36%), Gaps = 62/325 (19%)
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
+ A P +N +S +V + + LG+GT VY +
Sbjct 395 KAAVVVPSNVNTYTVSDLQVATNSFSVDNLLGEGTFGRVYRAQFEDGKVL---------- 444
Query 625 DPLVPGRDRGQELRVVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682
+K +D S D A F E S ++ + H ++ + G C +
Sbjct 445 ---------------AVKKIDSSALPTDTADDFTEIVSKIAHLDHENVTKLDGYCSEHGQ 489
Query 683 NIMVTEYVEHGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVC 736
+++V E+ +G L +L E P+ W ++ +A A AL YL + ++VH N+
Sbjct 490 HLVVYEFHRNGSLHDFLHLAEEESKPLIWNPRVKIALGTARALEYLHEVCSPSIVHKNIK 549
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER--IPWLAPECLPGGANSLSTA 794
NILL LSD G+ + E + + + APE G S
Sbjct 550 SANILLDSELNPH-------LSDSGLASFLPTANELLNQNDEGYSAPETSMSG--QYSLK 600
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL------------------PEP 836
D + FG +LE+ + +RS SE+ +L P
Sbjct 601 SDVYSFGVVMLELLTGRKPFDSTRSRSEQSLVRWATPQLHDIDALGKMVDPALKGLYPVK 660
Query 837 SCPQLATLTSQCLTYEPTQRPSFRT 861
S + A + + C+ EP RP
Sbjct 661 SLSRFADVIALCVQPEPEFRPPMSE 685
>sp|Q658G7|SIK1_ORYSJ LRR receptor-like serine/threonine-protein
kinase SIK1 OS=Oryza sativa subsp. japonica OX=39947 GN=SIK1
PE=1 SV=1
Length=980
Score = 224 bits (572), Expect = 4e-59, Method: Composition-based stats.
Identities = 74/358 (21%), Positives = 131/358 (37%), Gaps = 24/358 (7%)
Query 838 CPQLATLTSQC--LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895
C L + C L + +Q VL ++ + +
Sbjct 592 CIILGFIILLCVLLLAIYKTNQPQPLVKGSDKPVQGPPKLVVLQMDMAIHTYEDIMRLTE 651
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
L + +G G V +G+ +AVK L + R ++ E++ + ++
Sbjct 652 NLSEKYIIGYGASSTVYKCELK-----SGKAIAVKRLYSQYNHSLRE-FETELETIGSIR 705
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGM 1011
H +++ G L +Y+ GSL D L + + L A +G+
Sbjct 706 HRNLVSLHGFSLSPHGN--LLFYDYMENGSLWDLLHGPSKKVKLNWDTRLRIAVGAAQGL 763
Query 1012 AYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
AYLH IHRD+ + N+LLD + + DFG+AK VP + G + +
Sbjct 764 AYLHHDCNPRIIHRDVKSSNILLDENFEAHLSDFGIAKCVPSAKSHASTYVLG--TIGYI 821
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE + + SDV+SFG+ L ELLT + + ++ A + E +
Sbjct 822 DPEYARTSRLNEKSDVYSFGIVLLELLTGKKAVDNESNLHQLILSKADDNT----VMEAV 877
Query 1129 ERGERLPRPD-KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185
+ + D + + L C + S RPT + +L ++ P
Sbjct 878 DSEVSVTCTDMGLVRKAFQLALLCTKRHPSDRPTMHEVARVLLSLLPASAMTTPKTVD 935
Score = 188 bits (477), Expect = 2e-47, Method: Composition-based stats.
Identities = 54/300 (18%), Positives = 104/300 (35%), Gaps = 57/300 (19%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ +++ +G G + VY+ L+ + +K L
Sbjct 650 TENLSEKYIIGYGASSTVYKCELKSGK-------------------------AIAVKRLY 684
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
++ F + + H +L +HG + N++ +Y+E+G L L
Sbjct 685 SQYNHSLREFETELETIGSIRHRNLVSLHGFSLSPHGNLLFYDYMENGSLWDLLHGPSKK 744
Query 706 VPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
V + W ++ +A A L+YL N ++H +V NILL + LSD
Sbjct 745 VKLNWDTRLRIAVGAAQGLAYLHHDCNPRIIHRDVKSSNILLDE-------NFEAHLSDF 797
Query 761 GVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ S + I ++ PE + L+ D + FG LLE+ +A
Sbjct 798 GIAKCVPSAKSHASTYVLGTIGYIDPEYART--SRLNEKSDVYSFGIVLLELLTGKKAVD 855
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLA-------------TLTSQCLTYEPTQRPSFRTI 862
+ + + + E +++ L C P+ RP+ +
Sbjct 856 NESNLHQLILSKADDNTVMEAVDSEVSVTCTDMGLVRKAFQLALLCTKRHPSDRPTMHEV 915
>sp|Q39191|WAK1_ARATH Wall-associated receptor kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=WAK1 PE=1 SV=2
Length=735
Score = 221 bits (563), Expect = 4e-59, Method: Composition-based stats.
Identities = 71/279 (25%), Positives = 112/279 (40%), Gaps = 18/279 (6%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG+G G V +VA+K + Q + E+ +L + H +++K
Sbjct 415 LGQGGQGTVYKGIL-----PDNSIVAIKKARLGDSSQ-VEQFINEVLVLSQINHRNVVKL 468
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQ- 1017
GCC + E L LV E++ G+L D+L S+ L A ++ +AYLH+
Sbjct 469 LGCCLE-TEVPL-LVYEFITNGTLFDHLHGSMIDSSLTWEHRLKIAIEVAGTLAYLHSSA 526
Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
IHRD+ N+LLD + K+ DFG ++ +P E G + + PE
Sbjct 527 SIPIIHRDIKTANILLDVNLTAKVADFGASRLIPMDKEELETMVQG--TLGYLDPEYYNT 584
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
SDV+SFGV L ELL+ + P L+ RL E++
Sbjct 585 GLLNEKSDVYSFGVVLMELLSGQKALCFKRPQSSKHLVSYFATATKENRLDEIIGGEVMN 644
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
K E + C RP + + L+ +
Sbjct 645 EDNLKEIQEAARIAAECTRLMGEERPRMKEVAAKLEALR 683
Score = 207 bits (526), Expect = 2e-54, Method: Composition-based stats.
Identities = 79/484 (16%), Positives = 151/484 (31%), Gaps = 80/484 (17%)
Query 468 DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLR--KFPIEQQDGAFVLEGW-----G 520
DG + + ++ R + F + Q G + L+
Sbjct 271 DGNPYLSAGCQDVNECTTSSTIHRHNCSDPKTCRNKVGGFYCKCQSG-YRLDTTTMSCKR 329
Query 521 RSFPSVRELGAALQGCLL-RAGDDCFSLRRCCLPQPG--------ETSNLIIMRGARASP 571
+ F L G L+ G C R L ++ R + A P
Sbjct 330 KEFAWTTILLVTTIGFLVILLGVACIQQRMKHLKDTKLREQFFEQNGGGMLTQRLSGAGP 389
Query 572 RTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+++ + + + LGQG + VY+G L
Sbjct 390 SNVDVKIFTEDGMKKATNGYAESRILGQGGQGTVYKGILPDNSI---------------- 433
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
V +K F ++SQ++H ++ + G C+ ++V E+
Sbjct 434 ---------VAIKKARLGDSSQVEQFINEVLVLSQINHRNVVKLLGCCLETEVPLLVYEF 484
Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744
+ +G L L + W ++ +A ++A L+YL + ++H ++ NILL
Sbjct 485 ITNGTLFDHLHGSMIDSSLTWEHRLKIAIEVAGTLAYLHSSASIPIIHRDIKTANILLD- 543
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWG 799
+ K++D G +E + + +L PE G L+ D +
Sbjct 544 ------VNLTAKVADFGASRLIPMDKEELETMVQGTLGYLDPEYYNTGL--LNEKSDVYS 595
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQ-----RQHRLPEPS------------CPQLA 842
FG L+E+ +A R S K +++RL E + A
Sbjct 596 FGVVLMELLSGQKALCFKRPQSSKHLVSYFATATKENRLDEIIGGEVMNEDNLKEIQEAA 655
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902
+ ++C +RP + + L L+ + H +
Sbjct 656 RIAAECTRLMGEERPRMKEVAAKLEALRVEKTKHKWSDQYPEENEHLIGGHILSAQGETS 715
Query 903 LGEG 906
G
Sbjct 716 SSIG 719
>sp|P06245|KAPB_YEAST cAMP-dependent protein kinase type 2 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=TPK2 PE=1 SV=2
Length=380
Score = 211 bits (538), Expect = 4e-59, Method: Composition-based stats.
Identities = 75/346 (22%), Positives = 128/346 (37%), Gaps = 48/346 (14%)
Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916
P R + Q + + + P + + +R LG G FG+V L
Sbjct 30 PHHDLQQRQQQQQQRQHQQLLTSQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLV-- 87
Query 917 DPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974
+ G A+K LK + E +L+ + H +I+ G +D +++
Sbjct 88 --RSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDA--RNI 143
Query 975 QLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033
+VM+Y+ G L L + +A ++ + YLHA + I+RDL N+LLD
Sbjct 144 FMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDR 203
Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
+ +KI DFG AK E V + APE + + + D WS GV +YE
Sbjct 204 NGHIKITDFGFAK------EVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYE 257
Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
+L T ++ E + +G ++ P +V L+
Sbjct 258 MLAGYTPFYDT---------------TPMKTYEKILQG-KVVYPPYFHPDVVDLLSKLIT 301
Query 1154 TEASFR--------------PTFENLI-PIL--KTVHEKYQGQAPS 1182
+ + R P F ++ L K + Y+ S
Sbjct 302 ADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITS 347
Score = 172 bits (437), Expect = 1e-45, Method: Composition-based stats.
Identities = 55/285 (19%), Positives = 107/285 (38%), Gaps = 34/285 (12%)
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+ + S +S + + + LG G+ V+ +R +G K+
Sbjct 51 TSQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVH--LVRSVHNGRYYAIKVLK------ 102
Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689
++ V +K ++ ++ + ++ V H L + G MV +Y
Sbjct 103 -----KQQVVKMKQVEHTNDERR--------MLKLVEHPFLIRMWGTFQDARNIFMVMDY 149
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
+E G L LR+ + P A ++ AL YL N+++ ++ NILL R G
Sbjct 150 IEGGELFSLLRKSQ-RFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNG--- 205
Query 750 GTSPFIKLSDPGVGLGALSRE-ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
IK++D G + ++APE + + ++D W G + E+
Sbjct 206 ----HIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITT--KPYNKSVDWWSLGVLIYEML 259
Query 809 FDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQLATLTSQCLTYE 852
G P +P + + + P P + L S+ +T +
Sbjct 260 A-GYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITAD 303
>sp|Q95ZQ4|AAPK2_CAEEL 5'-AMP-activated protein kinase catalytic
subunit alpha-2 OS=Caenorhabditis elegans OX=6239 GN=aak-2
PE=1 SV=2
Length=626
Score = 218 bits (556), Expect = 4e-59, Method: Composition-based stats.
Identities = 82/291 (28%), Positives = 120/291 (41%), Gaps = 35/291 (12%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRT 953
+ LG G FGKV + ++ T VAVK L ++EI L
Sbjct 86 HYILKETLGVGTFGKVKVGIHE----TTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSL 141
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012
H HII+ + + ++ME+V G L DY+ +H + A+ F QQI G+
Sbjct 142 FRHPHIIRLYQVISTPSD--IFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVD 199
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
Y H +HRDL N+LLD VKI DFGL+ + +G +R SP + APE
Sbjct 200 YCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGD---FLRTSCGSPN-YAAPEV 255
Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ + DVWS GV LY LL V L ++ G
Sbjct 256 ISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEH---------------VPSLFRKIKSG 300
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182
P PD + +L+ + + R T +++I HE +Q P+
Sbjct 301 V-FPTPDFLERPIVNLLHHMLCVDPMKRATIKDVIA-----HEWFQKDLPN 345
Score = 175 bits (443), Expect = 2e-44, Method: Composition-based stats.
Identities = 53/317 (17%), Positives = 97/317 (31%), Gaps = 40/317 (13%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
T N M T +L ++ LG GT V
Sbjct 57 TDNSSKMSSPGGETSTKQQQELK-AQIKIGHYILKETLGVGTFGKV-------------- 101
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVH 674
G + +V +K+L+ D+ +S H H+ ++
Sbjct 102 ----------KVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHPHIIRLY 151
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGN 734
V + M+ E+V G L ++ + G + A QQ+ S + Y +VH +
Sbjct 152 QVISTPSDIFMIMEHVSGGELFDYIVKH-GRLKTAEARRFFQQIISGVDYCHRHMVVHRD 210
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSL 791
+ N+LL +K++D G+ + + APE + G +
Sbjct 211 LKPENLLLDEQN-------NVKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVISGKLYA- 262
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTY 851
+D W G L + PS P+ + L L
Sbjct 263 GPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHMLCV 322
Query 852 EPTQRPSFRTILRDLTR 868
+P +R + + ++
Sbjct 323 DPMKRATIKDVIAHEWF 339
>sp|Q6ERS0|CIPKR_ORYSJ Putative CBL-interacting protein kinase
27 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK27 PE=3
SV=1
Length=404
Score = 212 bits (540), Expect = 4e-59, Method: Composition-based stats.
Identities = 63/270 (23%), Positives = 110/270 (41%), Gaps = 27/270 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960
LG G+FG+V + + TG VA+K + D + K+EI +++ + H ++
Sbjct 17 LGHGNFGRV----HAARDVRTGRAVAMKVVSKDKVERAGMAEQIKREIAVMKMVSHPSVV 72
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ + + + L +E V G L D + RH +G + +Q+ + + H +
Sbjct 73 ELHEVMATRTK--VYLALELVRGGELFDRIARHGRVGEGVARRYFRQLVSAVDFCHGRGV 130
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
HRDL N+LLD +K+ DFGL+ + +P + APE L +
Sbjct 131 YHRDLKPENLLLDEAGNLKVADFGLSALACHARPDGLLHTACGTPA-YVAPEVLAGNGYD 189
Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+D+WS GV LY LL Q ++ + + RG+ P
Sbjct 190 GAKADLWSCGVILYVLLAGALPFQDD---------------NLVCMYRKMRRGD-FCCPP 233
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
+ L+K+ + R T L+
Sbjct 234 WVTTDARKLIKSLLDPNPGTRITVAGLLET 263
Score = 157 bits (397), Expect = 4e-40, Method: Composition-based stats.
Identities = 57/278 (21%), Positives = 88/278 (32%), Gaps = 52/278 (19%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
LG G V+ RD V +KV+
Sbjct 12 EMGRVLGHGNFGRVH------------------------AARDVRTGRAVAMKVVSKDKV 47
Query 650 D---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
+ +A ++M VSH + +H V + + E V G L + R G V
Sbjct 48 ERAGMAEQIKREIAVMKMVSHPSVVELHEVMATRTKVYLALELVRGGELFDRIARH-GRV 106
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV-GLG 765
+QL SA+ + + + H ++ N+LL G +K++D G+ L
Sbjct 107 GEGVARRYFRQLVSAVDFCHGRGVYHRDLKPENLLLDEAG-------NLKVADFGLSALA 159
Query 766 ALSR-----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+R ++APE L G D W G L + G P Q
Sbjct 160 CHARPDGLLHTACGTPAYVAPEVLAGNGYD-GAKADLWSCGVILY-VLLAGALPFQD--- 214
Query 821 SEKEHFYQRQHRLPEPSCPQLAT-----LTSQCLTYEP 853
+ R+ R + CP T L L P
Sbjct 215 -DNLVCMYRKMRRGDFCCPPWVTTDARKLIKSLLDPNP 251
>sp|F4I2N7|RLK7_ARATH Receptor-like protein kinase 7 OS=Arabidopsis
thaliana OX=3702 GN=RLK7 PE=1 SV=1
Length=977
Score = 224 bits (572), Expect = 4e-59, Method: Composition-based stats.
Identities = 67/318 (21%), Positives = 122/318 (38%), Gaps = 28/318 (9%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934
+ ++ S +K+ +G G G V G G+ VAVK ++
Sbjct 644 HESWSIKSFRKMSFTEDDIIDSIKEENLIGRGGCGDVYRVVL-----GDGKEVAVKHIRC 698
Query 935 DCGPQH--------------RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
++ ++ E+ L ++ H +++K C + S LV EY
Sbjct 699 SSTQKNFSSAMPILTEREGRSKEFETEVQTLSSIRHLNVVKLY--CSITSDDSSLLVYEY 756
Query 981 VPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDND 1034
+P GSL D L + ++G A +G+ YLH + IHRD+ + N+LLD
Sbjct 757 LPNGSLWDMLHSCKKSNLGWETRYDIALGAAKGLEYLHHGYERPVIHRDVKSSNILLDEF 816
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP-ECLKEYKFYYASDVWSFGVTLYE 1093
+I DFGLAK + + + AP E K DV+SFGV L E
Sbjct 817 LKPRIADFGLAKILQASNGGPESTHVVAGTYGYIAPAEYGYASKVTEKCDVYSFGVVLME 876
Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
L+T ++ + +++ + + + + ++ + C
Sbjct 877 LVTGKKPIEAEFGESKDIVNWVSNNLKSKESVMEIVDKKIGEMYREDAVKMLRIAIICTA 936
Query 1154 TEASFRPTFENLIPILKT 1171
RPT +++ +++
Sbjct 937 RLPGLRPTMRSVVQMIED 954
Score = 182 bits (462), Expect = 2e-45, Method: Composition-based stats.
Identities = 48/272 (18%), Positives = 101/272 (37%), Gaps = 33/272 (12%)
Query 575 NLSQLSFHRVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
+ ++SF D + I + + +G+G +VY L + +
Sbjct 651 SFRKMSFTEDDIIDSIKEENLIGRGGCGDVYRVVLGDGKEVAVKHIRCSSTQKNFSS--- 707
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ +L + F +S + H ++ ++ +++V EY+ +G
Sbjct 708 ------AMPILTEREG-RSKEFETEVQTLSSIRHLNVVKLYCSITSDDSSLLVYEYLPNG 760
Query 694 PLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAE 749
L L ++ ++ + +A A L YL + ++H +V NILL
Sbjct 761 SLWDMLHSCKKSNLGWETRYDIALGAAKGLEYLHHGYERPVIHRDVKSSNILLDEFLKP- 819
Query 750 GTSPFIKLSDPGVGL-------GALSREERVERIPWLAP-ECLPGGANSLSTAMDKWGFG 801
+++D G+ G S ++AP E G A+ ++ D + FG
Sbjct 820 ------RIADFGLAKILQASNGGPESTHVVAGTYGYIAPAEY--GYASKVTEKCDVYSFG 871
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833
L+E+ G+ P+++ K+ + L
Sbjct 872 VVLMELV-TGKKPIEAEFGESKDIVNWVSNNL 902
>sp|Q94CU5|NEK5_ORYSJ Serine/threonine-protein kinase Nek5 OS=Oryza
sativa subsp. japonica OX=39947 GN=NEK5 PE=2 SV=1
Length=943
Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats.
Identities = 63/294 (21%), Positives = 120/294 (41%), Gaps = 30/294 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEI 948
+ + +G G FG L + +K ++ A + R QE+
Sbjct 1 MDSRMDQYEVMEQIGRGAFGAAILVNHKTEKK----KYVLKKIRLARQTERCRKSAHQEM 56
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQ 1005
++ L H +I+++K ++G + +V Y G + + + + + +LL +
Sbjct 57 ALIARLQHPYIVEFKEAWVEKG-CYVCIVTGYCEGGDMAELMKKANGTYFPEEKLLKWFA 115
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
Q+ + YLH+ +HRDL N+ L D+ +++GDFGLAK + +
Sbjct 116 QLALAVDYLHSNFVLHRDLKCSNIFLTKDQDIRLGDFGLAKTLKADD----LTSSVVGTP 171
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+ PE L + + + SD+WS G +YE+ ++ P K ++ G L
Sbjct 172 NYMCPELLADIPYGFKSDIWSLGCCMYEM-----AAHRPAFKAFDMAG----------LI 216
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQ 1177
+ R P P + L+K+ RPT ++ P L+ +Y+
Sbjct 217 SKINRSSIGPLPPCYSPSMKSLIKSMLRKSPEHRPTASEILKSPYLQPYVNQYR 270
Score = 151 bits (382), Expect = 6e-36, Method: Composition-based stats.
Identities = 53/311 (17%), Positives = 101/311 (32%), Gaps = 41/311 (13%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
R+DQ E+ + +G+G ++ ++ V+ K
Sbjct 4 RMDQYEV--MEQIGRGAFG-----------------------AAILVNHKTEKKKYVLKK 38
Query 643 -VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLR 700
L + ++ +L++++ H ++ V +VT Y E G + ++
Sbjct 39 IRLARQTERCRKSAHQEMALIARLQHPYIVEFKEAWVEKGCYVCIVTGYCEGGDMAELMK 98
Query 701 RERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ G + P + QLA A+ YL + ++H ++ NI L + I+L D
Sbjct 99 KANGTYFPEEKLLKWFAQLALAVDYLHSNFVLHRDLKCSNIFLTK-------DQDIRLGD 151
Query 760 PGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL- 815
G+ + + V ++ PE L D W G + E+ A
Sbjct 152 FGLAKTLKADDLTSSVVGTPNYMCPELLADIPYGF--KSDIWSLGCCMYEMAAHRPAFKA 209
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ + LP P + +L L P RP+ IL+ N
Sbjct 210 FDMAGLISKINRSSIGPLPPCYSPSMKSLIKSMLRKSPEHRPTASEILKSPYLQPYVNQY 269
Query 876 DVLTVNPDSPA 886
Sbjct 270 RPFADISHPIH 280
>sp|Q9M0T3|MP3K3_ARATH Mitogen-activated protein kinase kinase
kinase 3 OS=Arabidopsis thaliana OX=3702 GN=MEKK3 PE=2 SV=1
Length=560
Score = 217 bits (552), Expect = 4e-59, Method: Composition-based stats.
Identities = 78/333 (23%), Positives = 125/333 (38%), Gaps = 38/333 (11%)
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD--- 902
S C P+ R R + V F K
Sbjct 248 STCSLMTPSMEFPDRISFRKRDFSEEGPSGRVKEKRKLMRNKLIENFRKPEDITSWLKGQ 307
Query 903 -LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQ---EIDILRTLYHE 957
LG G + V G+ AVK + D G Q + +Q EI +L L H+
Sbjct 308 LLGRGSYASVYEAI-----SEDGDFFAVKEVSLLDKGIQAQECIQQLEGEIALLSQLQHQ 362
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017
+I++Y+G + L + +E V GS++ R+ + + L+ +QI G+ YLH +
Sbjct 363 NIVRYRG--TAKDVSKLYIFLELVTQGSVQKLYERYQLSYTVVSLYTRQILAGLNYLHDK 420
Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
++HRD+ N+L+D + VK+ DFGLA+A +FW APE +
Sbjct 421 GFVHRDIKCANMLVDANGTVKLADFGLAEASKFNDI-----MSCKGTLFWMAPEVINRKD 475
Query 1078 FY---YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
+D+WS G T+ E+ T I + ++ + RG
Sbjct 476 SDGNGSPADIWSLGCTVLEMCTG---------------QIPYSDLKPIQAAFKIGRGTLP 520
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
PD + H + C + RPT L+
Sbjct 521 DVPDTLSLDARHFILTCLKVNPEERPTAAELLH 553
Score = 179 bits (454), Expect = 3e-46, Method: Composition-based stats.
Identities = 76/424 (18%), Positives = 142/424 (33%), Gaps = 56/424 (13%)
Query 472 LIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKF-----------PIEQQDGAFVLEGWG 520
L+ S P R+ S+ RK P + + L+G
Sbjct 167 LMTPSLEFPDRISFRKKDFSEKGPSRHVWEKRKLTRAKLIENFCNPEDIEPVTSWLKGQL 226
Query 521 RSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETS------NLIIMRGARASPRTL 574
S + A+ + + C SL + P S + G R L
Sbjct 227 LGEESFASVYEAISDSSVGSESTC-SLMTPSMEFPDRISFRKRDFSEEGPSGRVKEKRKL 285
Query 575 NLSQLSFHRVDQKEIT---QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
++L + ++IT + LG+G+ +VYE +E + D+
Sbjct 286 MRNKLIENFRKPEDITSWLKGQLLGRGSYASVYEAISEDGDFFAVKEVSLLDKGIQA--- 342
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+ +L+SQ+ H ++ G + + E V
Sbjct 343 -----------------QECIQQLEGEIALLSQLQHQNIVRYRGTAKDVSKLYIFLELVT 385
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
G + ER + + +Q+ + L+YL +K VH ++ N+L+
Sbjct 386 QGSVQKL--YERYQLSYTVVSLYTRQILAGLNYLHDKGFVHRDIKCANMLVD-------A 436
Query 752 SPFIKLSDPGVGLGALSRE--ERVERIPWLAPECL-PGGANSLSTAMDKWGFGATLLEIC 808
+ +KL+D G+ + + + W+APE + ++ + D W G T+LE+C
Sbjct 437 NGTVKLADFGLAEASKFNDIMSCKGTLFWMAPEVINRKDSDGNGSPADIWSLGCTVLEMC 496
Query 809 FDGEAPLQSRSPSEKEHFYQRQ--HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
G+ P P + R +P+ CL P +RP+ +L
Sbjct 497 -TGQIPYSDLKPIQAAFKIGRGTLPDVPDTLSLDARHFILTCLKVNPEERPTAAELLHHP 555
Query 867 TRLQ 870
+
Sbjct 556 FVIN 559
>sp|Q7RZD3|STE20_NEUCR Serine/threonine-protein kinase ste20 OS=Neurospora
crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71
/ DSM 1257 / FGSC 987) OX=367110 GN=stk-4 PE=3 SV=1
Length=954
Score = 224 bits (571), Expect = 5e-59, Method: Composition-based stats.
Identities = 57/274 (21%), Positives = 114/274 (42%), Gaps = 23/274 (8%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
+ + +G+G G V G+ +VA+K + + P+ + EI +++
Sbjct 670 PREIYRGFTKIGQGASGGVYTGH----ERGSNRLVAIKQMNLEQQPK-KDLIINEILVMK 724
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
H +I+ + GE L +VMEY+ GSL D + + + Q+ ++ G+
Sbjct 725 ESSHPNIVNFIDSYLCAGE--LWVVMEYMEGGSLTDVVTFNIMTEGQIASVCRETLRGLQ 782
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+LH++ IHRD+ + N+LL + +K+ DFG + +E R +W APE
Sbjct 783 HLHSKGVIHRDIKSDNILLSMEGNIKLTDFGFCATI---NEAQSKRTTMVGTPYWMAPEV 839
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ ++ D+WS G+ E++ + + L IA ++ + L
Sbjct 840 VTRKEYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALWLIATNGTPHIKDEQSLSPVF 898
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
R + + + + R + +L+
Sbjct 899 R---------DFLYFA---LKVDPEKRASAHDLL 920
Score = 184 bits (468), Expect = 2e-46, Method: Composition-based stats.
Identities = 60/315 (19%), Positives = 103/315 (33%), Gaps = 44/315 (14%)
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
R + A +L ++ ++ + +GQG VY G
Sbjct 650 RQSNAIDVVASLKRICSDGDPREIYRGFTKIGQGASGGVYTGH----------------- 692
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+RG V +K ++ +M + SH ++ + E
Sbjct 693 -------ERGSNRLVAIKQMNLEQQPKKDLIINEILVMKESSHPNIVNFIDSYLCAGELW 745
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+V EY+E G L + + V ++ L +L +K ++H ++ NILL+
Sbjct 746 VVMEYMEGGSLTDVV--TFNIMTEGQIASVCRETLRGLQHLHSKGVIHRDIKSDNILLSM 803
Query 745 LGLAEGTSPFIKLSDPGVGLGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800
G IKL+D G R V W+APE + +D W
Sbjct 804 EG-------NIKLTDFGFCATINEAQSKRTTMVGTPYWMAPEVVT--RKEYGRKVDIWSL 854
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP----EPSCPQLATLTSQCLTYEPTQR 856
G +E+ +GE P + SP + P L +P +R
Sbjct 855 GIMAIEMI-EGEPPYLTESPLRALWLIATNGTPHIKDEQSLSPVFRDFLYFALKVDPEKR 913
Query 857 PSFRTILRDLTRLQP 871
S +LR +
Sbjct 914 ASAHDLLRHDFMNKC 928
>sp|P57059|SIK1_HUMAN Serine/threonine-protein kinase SIK1 OS=Homo
sapiens OX=9606 GN=SIK1 PE=1 SV=2
Length=783
Score = 221 bits (564), Expect = 5e-59, Method: Composition-based stats.
Identities = 66/273 (24%), Positives = 107/273 (39%), Gaps = 29/273 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTL 954
+ R LG+G+F V L + T VA+K + K + +E+ +++ L
Sbjct 26 FYDIERTLGKGNFAVVKL----ARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLL 81
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAY 1013
H HIIK E + L +V E+ G + DYL + + + QI + Y
Sbjct 82 NHPHIIKLYQVMETKD--MLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEY 139
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
H H +HRDL N+LLD + +K+ DFG G + SP + APE
Sbjct 140 CHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEP---LSTWCGSPP-YAAPEVF 195
Query 1074 KEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ ++ D+WS GV LY L+ P + L + + G
Sbjct 196 EGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGP---------------NLPTLRQRVLEG- 239
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
R P + L++ + + R T +
Sbjct 240 RFRIPFFMSQDCESLIRRMLVVDPARRITIAQI 272
Score = 200 bits (509), Expect = 5e-52, Method: Composition-based stats.
Identities = 66/351 (19%), Positives = 117/351 (33%), Gaps = 40/351 (11%)
Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620
++IM A P Q RV +I LG+G V R RV
Sbjct 1 MVIMSEFSADPAGQGQGQQKPLRVGFYDIE--RTLGKGNFAVVKLARHRV---------- 48
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCV 678
+ +V +K++D + D + Y LM ++H H+ ++ V
Sbjct 49 --------------TKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVME 94
Query 679 RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGR 738
+VTE+ ++G + +L GH+ Q+ SA+ Y + ++VH ++
Sbjct 95 TKDMLYIVTEFAKNGEMFDYLTSN-GHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTE 153
Query 739 NILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAM 795
N+LL + IKL+D G G P+ APE G +
Sbjct 154 NLLLD-------GNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYE-GPQL 205
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855
D W G L + P+ ++ + + R+P +L + L +P +
Sbjct 206 DIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDPAR 265
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906
R + I + L + + + G
Sbjct 266 RITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSNLGDYDEQALGIMQTLG 316
>sp|A0A0B4J2F2|SIK1B_HUMAN Putative serine/threonine-protein kinase
SIK1B OS=Homo sapiens OX=9606 GN=SIK1B PE=5 SV=1
Length=783
Score = 221 bits (564), Expect = 5e-59, Method: Composition-based stats.
Identities = 66/273 (24%), Positives = 107/273 (39%), Gaps = 29/273 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTL 954
+ R LG+G+F V L + T VA+K + K + +E+ +++ L
Sbjct 26 FYDIERTLGKGNFAVVKL----ARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLL 81
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAY 1013
H HIIK E + L +V E+ G + DYL + + + QI + Y
Sbjct 82 NHPHIIKLYQVMETKD--MLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEY 139
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
H H +HRDL N+LLD + +K+ DFG G + SP + APE
Sbjct 140 CHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEP---LSTWCGSPP-YAAPEVF 195
Query 1074 KEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ ++ D+WS GV LY L+ P + L + + G
Sbjct 196 EGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGP---------------NLPTLRQRVLEG- 239
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
R P + L++ + + R T +
Sbjct 240 RFRIPFFMSQDCESLIRRMLVVDPARRITIAQI 272
Score = 200 bits (509), Expect = 5e-52, Method: Composition-based stats.
Identities = 66/351 (19%), Positives = 117/351 (33%), Gaps = 40/351 (11%)
Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620
++IM A P Q RV +I LG+G V R RV
Sbjct 1 MVIMSEFSADPAGQGQGQQKPLRVGFYDIE--RTLGKGNFAVVKLARHRV---------- 48
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCV 678
+ +V +K++D + D + Y LM ++H H+ ++ V
Sbjct 49 --------------TKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVME 94
Query 679 RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGR 738
+VTE+ ++G + +L GH+ Q+ SA+ Y + ++VH ++
Sbjct 95 TKDMLYIVTEFAKNGEMFDYLTSN-GHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTE 153
Query 739 NILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAM 795
N+LL + IKL+D G G P+ APE G +
Sbjct 154 NLLLD-------GNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYE-GPQL 205
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855
D W G L + P+ ++ + + R+P +L + L +P +
Sbjct 206 DIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDPAR 265
Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906
R + I + L + + + G
Sbjct 266 RITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSNLGDYDEQALGIMQTLG 316
>sp|Q40531|NTF6_TOBAC Mitogen-activated protein kinase homolog
NTF6 OS=Nicotiana tabacum OX=4097 GN=NTF6 PE=2 SV=1
Length=371
Score = 211 bits (537), Expect = 5e-59, Method: Composition-based stats.
Identities = 77/337 (23%), Positives = 133/337 (39%), Gaps = 35/337 (10%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL- 932
+ + +Y+ I+ +G G +G V TN T E VA+K +
Sbjct 15 PTHEGKYVEYNVLGNFFEVTSKYIPPIQPVGRGAYGMVCC----ATNSETKEEVAIKKIG 70
Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK---SLQLVMEYVPLGSLRDY 989
A +EI +L + HE+IIK K + + +V E + L
Sbjct 71 NAFENRIDAKRTLREIKLLSHMDHENIIKIKDIVRPPDREEFNDVYIVYELMD-TDLHQI 129
Query 990 LPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048
+ ++ F Q+ G+ Y+H+ + +HRDL N+LL+ + +KI DFGLA+
Sbjct 130 IRSSQALTDDHCQYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKICDFGLARTT 189
Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
E + ++ APE L ++ A D+WS G L EL+
Sbjct 190 SEAD----FMTEYVVTRWYRAPELLLNCTEYTAAIDIWSVGCILMELIKREPLFPGRDYA 245
Query 1108 -----FLELIGIAQ----GQMTVLRLTELLERGERLPR-------PDKCPCEVYHLMKNC 1151
+ L+G + G + + ++ R+PR PD P + L +
Sbjct 246 QQLGLIIALLGSPEDSDLGFLRSDNARKYVKHLPRVPRHPFSQKFPDVSPLAL-DLAERM 304
Query 1152 WETEASFRPTFENLI--PILKTVHEKYQGQA-PSVFS 1185
+ + R T E+ + P L ++HE + S F+
Sbjct 305 LVFDPAKRITVEDALNHPFLISLHEINEEPVCDSPFN 341
Score = 132 bits (333), Expect = 5e-32, Method: Composition-based stats.
Identities = 41/238 (17%), Positives = 79/238 (33%), Gaps = 44/238 (18%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
F V K I + +G+G V + + V
Sbjct 30 FFEVTSKYIPPIQPVGRGAYGMVC------------------------CATNSETKEEVA 65
Query 641 LKVLDPSHHDIALAF--YETASLMSQVSHTHLAFVHGVCV-----RGPENIMVTEYVEHG 693
+K + + + A L+S + H ++ + + + +V E ++
Sbjct 66 IKKIGNAFENRIDAKRTLREIKLLSHMDHENIIKIKDIVRPPDREEFNDVYIVYELMD-T 124
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L +R + + QL L Y+ + N++H ++ N+LL +
Sbjct 125 DLHQIIRSSQA-LTDDHCQYFLYQLLRGLKYVHSANVLHRDLKPSNLLLN-------ANC 176
Query 754 FIKLSDPGVGLGALS---REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+K+ D G+ E V + APE L + A+D W G L+E+
Sbjct 177 DLKICDFGLARTTSEADFMTEYVVTRWYRAPELLLNCTE-YTAAIDIWSVGCILMELI 233
>sp|Q9LVP0|Y5639_ARATH Probable leucine-rich repeat receptor-like
protein kinase At5g63930 OS=Arabidopsis thaliana OX=3702
GN=At5g63930 PE=1 SV=1
Length=1102
Score = 225 bits (574), Expect = 5e-59, Method: Composition-based stats.
Identities = 76/339 (22%), Positives = 127/339 (37%), Gaps = 22/339 (6%)
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902
+L L +RP D+ + V +
Sbjct 750 SLMLIALIVYLMRRPVRTVASSAQDGQPSEMSLDIYFPPKEGFTFQDLVAATDNFDESFV 809
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH----RSGWKQEIDILRTLYHEH 958
+G G G V G +AVK L ++ + + ++ EI L + H +
Sbjct 810 VGRGACGTVYKAVLPA-----GYTLAVKKLASNHEGGNNNNVDNSFRAEILTLGNIRHRN 864
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHA 1016
I+K G C QG L+ EY+P GSL + L S + ++ A +G+AYLH
Sbjct 865 IVKLHGFCNHQGSN--LLLYEYMPKGSLGEILHDPSCNLDWSKRFKIALGAAQGLAYLHH 922
Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
HRD+ + N+LLD+ +GDFGLAK + H + + APE
Sbjct 923 DCKPRIFHRDIKSNNILLDDKFEAHVGDFGLAKVIDMPHS--KSMSAIAGSYGYIAPEYA 980
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
K SD++S+GV L ELLT Q P + +++ + + L+ +
Sbjct 981 YTMKVTEKSDIYSYGVVLLELLTGKAPVQ-PIDQGGDVVNWVRSYIRRDALSSGVLDARL 1039
Query 1134 LPRPDKCPCEV---YHLMKNCWETEASFRPTFENLIPIL 1169
++ + + C RP+ ++ +L
Sbjct 1040 TLEDERIVSHMLTVLKIALLCTSVSPVARPSMRQVVLML 1078
Score = 190 bits (483), Expect = 6e-48, Method: Composition-based stats.
Identities = 54/314 (17%), Positives = 102/314 (32%), Gaps = 69/314 (22%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ +G+G VY+ L + +K L
Sbjct 800 ATDNFDESFVVGRGACGTVYKAVLPAGYTL-------------------------AVKKL 834
Query 645 DPSHH-----DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+H ++ +F + + H ++ +HG C N+++ EY+ G L L
Sbjct 835 ASNHEGGNNNNVDNSFRAEILTLGNIRHRNIVKLHGFCNHQGSNLLLYEYMPKGSLGEIL 894
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIK 756
++ + + +A A L+YL + + H ++ NILL A
Sbjct 895 HDPSCNLDWSKRFKIALGAAQGLAYLHHDCKPRIFHRDIKSNNILLDDKFEAH------- 947
Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
+ D G+ + S ++APE ++ D + +G LLE+ G
Sbjct 948 VGDFGLAKVIDMPHSKSMSAIAGSYGYIAPEYA--YTMKVTEKSDIYSYGVVLLELL-TG 1004
Query 812 EAPLQSRSPSEKEHFYQRQH--------------------RLPEPSCPQLATLTSQCLTY 851
+AP+Q + R + R+ L + C +
Sbjct 1005 KAPVQPIDQGGDVVNWVRSYIRRDALSSGVLDARLTLEDERIVSHMLTVL-KIALLCTSV 1063
Query 852 EPTQRPSFRTILRD 865
P RPS R ++
Sbjct 1064 SPVARPSMRQVVLM 1077
>sp|Q12263|GIN4_YEAST Serine/threonine-protein kinase GIN4 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=GIN4 PE=1 SV=1
Length=1142
Score = 225 bits (574), Expect = 5e-59, Method: Composition-based stats.
Identities = 76/290 (26%), Positives = 118/290 (41%), Gaps = 40/290 (14%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS------------- 942
K LG G GKV L N TG+ AVK +
Sbjct 18 PWKLGETLGLGSTGKVQL----ARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDA 73
Query 943 ---GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLA 998
G ++EI I++ L H ++++ E + L LV+EY G L + L R +
Sbjct 74 LPYGIEREIIIMKLLNHPNVLRLYDVWETNTD--LYLVLEYAEKGELFNLLVERGPLPEH 131
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
+ + F +QI G++Y HA +HRDL N+LLD+ +KI DFG+A EG ++
Sbjct 132 EAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEG----KLL 187
Query 1059 EDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
E + APE + + +ASDVWS GV L+ LLT L
Sbjct 188 ETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTL------ 241
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L ++ + +P D+ E L++ + R +++
Sbjct 242 ------LLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILK 285
Score = 167 bits (423), Expect = 1e-40, Method: Composition-based stats.
Identities = 56/299 (19%), Positives = 104/299 (35%), Gaps = 25/299 (8%)
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
++ + + + ++ LG G+ V R +G K+ + G G
Sbjct 7 SIPAIKDNTIGPWKL--GETLGLGSTGKV--QLARNGSTGQEAAVKVISKAVFNTGNVSG 62
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+ V + + +M ++H ++ ++ V + +V EY E G
Sbjct 63 TSI-----VGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGE 117
Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754
L L ERG +P + +Q+ +SY +VH ++ N+LL
Sbjct 118 LFNLL-VERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHK-------YN 169
Query 755 IKLSDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
IK++D G+ E + APE + G A D W G L +
Sbjct 170 IKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQ-GFASDVWSCGVILFALLTGR 228
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLA----TLTSQCLTYEPTQRPSFRTILRDL 866
+ ++ PS +++ L + LT +P +R R IL+
Sbjct 229 LPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHP 287
>sp|Q9C8M9|SRF6_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 6 OS=Arabidopsis
thaliana OX=3702 GN=SRF6 PE=1 SV=1
Length=719
Score = 220 bits (561), Expect = 5e-59, Method: Composition-based stats.
Identities = 66/273 (24%), Positives = 121/273 (44%), Gaps = 23/273 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIK 961
LGEG FG+V +D G+++AVK + + P + + + + L H ++ K
Sbjct 422 LGEGTFGRVYRAEFD-----DGKVLAVKKIDSSALPHGMTDDFIEMVSKIANLDHPNVTK 476
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMAYLH- 1015
G C + G+ +V E+ GSL D+L ++ + A + YLH
Sbjct 477 LVGYCAEHGQH--LVVYEFHKNGSLHDFLHLSEEESKALVWNSRVKIALGTARALEYLHE 534
Query 1016 --AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ + +++ + N+LLD++ + D GLA +P +E ++G + APE
Sbjct 535 VCSPSIVDKNIKSANILLDSELNPHLSDSGLASFLPTANELLNQTDEG-----YSAPEVS 589
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQM-TVLRLTELLERG 1131
++ SD++SFGV + ELLT S ++ L+ A Q+ + L ++++
Sbjct 590 MSGQYSLKSDIYSFGVVMLELLTGRKPFDSTRSRSEQSLVRWATPQLHDIDALAKMVDPA 649
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ P K ++ C + E FRP
Sbjct 650 LKGLYPVKSLSRFADVIALCVQPEPEFRPPMSE 682
Score = 180 bits (457), Expect = 1e-45, Method: Composition-based stats.
Identities = 67/329 (20%), Positives = 120/329 (36%), Gaps = 62/329 (19%)
Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620
+ + + P + L ++ ++ + + LG+GT VY +
Sbjct 388 IAVKKSTVVVPSNVRLYSVADLQIATGSFSVDNLLGEGTFGRVYRA-------------E 434
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCV 678
DD L +K +D S H + F E S ++ + H ++ + G C
Sbjct 435 FDDGKVL------------AVKKIDSSALPHGMTDDFIEMVSKIANLDHPNVTKLVGYCA 482
Query 679 RGPENIMVTEYVEHGPLDVWLR---RERGHVPMAWKMVVAQQLASALSYLE---NKNLVH 732
++++V E+ ++G L +L E + ++ +A A AL YL + ++V
Sbjct 483 EHGQHLVVYEFHKNGSLHDFLHLSEEESKALVWNSRVKIALGTARALEYLHEVCSPSIVD 542
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--PWLAPECLPGGANS 790
N+ NILL LSD G+ + E + + + APE G
Sbjct 543 KNIKSANILLDSELNPH-------LSDSGLASFLPTANELLNQTDEGYSAPEVSMSG--Q 593
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL----------------- 833
S D + FG +LE+ + +RS SE+ +L
Sbjct 594 YSLKSDIYSFGVVMLELLTGRKPFDSTRSRSEQSLVRWATPQLHDIDALAKMVDPALKGL 653
Query 834 -PEPSCPQLATLTSQCLTYEPTQRPSFRT 861
P S + A + + C+ EP RP
Sbjct 654 YPVKSLSRFADVIALCVQPEPEFRPPMSE 682
>sp|A0A1S4CGX4|SIPKK_TOBAC Mitogen-activated protein kinase kinase
SIPKK OS=Nicotiana tabacum OX=4097 GN=SIPKK PE=1 SV=1
Length=357
Score = 210 bits (535), Expect = 5e-59, Method: Composition-based stats.
Identities = 64/267 (24%), Positives = 120/267 (45%), Gaps = 20/267 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G+ G V L + TG+ A+K ++ + R QE+ I ++ +++
Sbjct 76 IGKGNGGIVRLVQHK----WTGQFFALKVIQMNIEESMRKHIAQELRINQSSQCPYVVIS 131
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHA-QHYI 1020
D G ++ +++EY+ GSL D+L + +I L +Q+ +G+ YLH +H I
Sbjct 132 YQSFFDNG--AISIILEYMDGGSLADFLKKVKTIPERYLAAICKQVLKGLWYLHHEKHII 189
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDL N+L+++ VKI DFG++ + + + +PE + + Y
Sbjct 190 HRDLKPSNLLINHIGDVKITDFGVSAVLASTSG---LANTFVGTYNYMSPERILGGAYGY 246
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE-LLERGERLPRPDK 1139
SD+WS G+ L E T P +G + V L E ++++ PD+
Sbjct 247 RSDIWSLGLVLLECATGVFPYSPPQAD--------EGWVNVYELMETIVDQPAPSAPPDQ 298
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLI 1166
+ + C + + R + L+
Sbjct 299 FSPQFCSFISACVQKDQKDRLSANELM 325
Score = 160 bits (405), Expect = 1e-41, Method: Composition-based stats.
Identities = 59/330 (18%), Positives = 117/330 (35%), Gaps = 60/330 (18%)
Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620
I+ + +P + S +++ + + +G+G V
Sbjct 45 RIVSQSEVEAPSVIQPSD---NQLCLADFEAVKVIGKGNGGIV----------------- 84
Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVR 679
LV + GQ LKV+ + + + + ++ +
Sbjct 85 -----RLVQHKWTGQFF--ALKVIQMNIEESMRKHIAQELRINQSSQCPYVVISYQSFFD 137
Query 680 GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE-NKNLVHGNVCGR 738
++ EY++ G L +L++ + +P + + +Q+ L YL K+++H ++
Sbjct 138 NGAISIILEYMDGGSLADFLKKVK-TIPERYLAAICKQVLKGLWYLHHEKHIIHRDLKPS 196
Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSRE----ERVERIPWLAPECLPGGANSLSTA 794
N+L+ +G +K++D GV S V +++PE + GGA
Sbjct 197 NLLINHIGD-------VKITDFGVSAVLASTSGLANTFVGTYNYMSPERILGGAYGY--R 247
Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-------------PEPSCPQL 841
D W G LLE C G P SP + + + + L P+ PQ
Sbjct 248 SDIWSLGLVLLE-CATGVFPY---SPPQADEGWVNVYELMETIVDQPAPSAPPDQFSPQF 303
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
+ S C+ + R S ++R
Sbjct 304 CSFISACVQKDQKDRLSANELMRHPFITMY 333
>sp|I1Z695|EREC2_ORYSJ LRR receptor-like serine/threonine-protein
kinase ER2 OS=Oryza sativa subsp. japonica OX=39947 GN=ER2
PE=1 SV=2
Length=986
Score = 224 bits (571), Expect = 5e-59, Method: Composition-based stats.
Identities = 73/342 (21%), Positives = 129/342 (38%), Gaps = 26/342 (8%)
Query 841 LATLTSQCL---TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897
L L + C P + + L +L +N + + L
Sbjct 594 LMILAAACWPHWAQVPKDVSLCKPDIHALPSSNVPPKLVILHMNMAFLVYEDIMRMTENL 653
Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957
+ +G G V + VA+K L A PQ ++ E++ + ++ H
Sbjct 654 SEKYIIGYGASSTVYKCVLKNC-----KPVAIKKLYAHY-PQSLKEFETELETVGSIKHR 707
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMA 1012
+++ +G L +Y+ GSL D L + + L A +G+A
Sbjct 708 NLVSLQGYSLSPAGN--LLFYDYLENGSLWDVLHAGSSKKQKLDWEARLRIALGAAQGLA 765
Query 1013 YLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
YLH IHRD+ ++N+LLD D + DFG+AK++ + + +
Sbjct 766 YLHHDCNPRIIHRDVKSKNILLDKDYEAHLADFGIAKSLCTSKTH--TSTYVMGTIGYID 823
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE + SDV+S+G+ L ELLT P L + + + E+++
Sbjct 824 PEYACTSRLNEKSDVYSYGIVLLELLTGK----KPVDNECNLHHLILSKAADNTVMEMVD 879
Query 1130 RGERLPRPD-KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
D +V+ L C + + S RPT ++ +L
Sbjct 880 PDIADTCKDLGEVKKVFQLALLCSKRQPSDRPTMHEVVRVLD 921
Score = 184 bits (468), Expect = 3e-46, Method: Composition-based stats.
Identities = 56/329 (17%), Positives = 117/329 (36%), Gaps = 60/329 (18%)
Query 573 TLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
+N++ L + + + + +++ +G G + VY+ L+
Sbjct 635 HMNMAFLVYEDIMRMTENLSEKYIIGYGASSTVYKCVLKNCKP----------------- 677
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
V +K L + F + + H +L + G + N++ +Y+
Sbjct 678 --------VAIKKLYAHYPQSLKEFETELETVGSIKHRNLVSLQGYSLSPAGNLLFYDYL 729
Query 691 EHGPLDVWLR---RERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLAR 744
E+G L L ++ + ++ +A A L+YL N ++H +V +NILL +
Sbjct 730 ENGSLWDVLHAGSSKKQKLDWEARLRIALGAAQGLAYLHHDCNPRIIHRDVKSKNILLDK 789
Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWG 799
A L+D G+ + + + I ++ PE + L+ D +
Sbjct 790 DYEAH-------LADFGIAKSLCTSKTHTSTYVMGTIGYIDPEYA--CTSRLNEKSDVYS 840
Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT-------------LTS 846
+G LLE+ + + + + E P +A L
Sbjct 841 YGIVLLELLTGKKPVDNECNLHHLILSKAADNTVMEMVDPDIADTCKDLGEVKKVFQLAL 900
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
C +P+ RP+ ++R L L +
Sbjct 901 LCSKRQPSDRPTMHEVVRVLDCLVYPDPP 929
>sp|Q7FAZ0|LERK4_ORYSJ G-type lectin S-receptor-like serine/threonine-protein
kinase LECRK4 OS=Oryza sativa subsp. japonica
OX=39947 GN=LECRK4 PE=3 SV=1
Length=804
Score = 222 bits (565), Expect = 6e-59, Method: Composition-based stats.
Identities = 66/274 (24%), Positives = 112/274 (41%), Gaps = 14/274 (5%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G G V D G +AVK + + + E+ + YH+++++
Sbjct 520 LGTGASGIVYKGQLQ---DELGTYIAVKKIDKIQHETEKE-FAVEVQTIGRTYHKNLVRM 575
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH---AQH 1018
G C + E+ LV E++ GSL +L + + A + G+ YLH +
Sbjct 576 LGFCNEGTER--LLVYEFMVNGSLNRFLFSGVRPLWSLRVQLALGVARGLLYLHEECSTQ 633
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IH D+ +N+LLD++ + KI DFGLAK + + + APE K
Sbjct 634 IIHCDIKPQNILLDDNFIAKISDFGLAKLLRTNQT--QTYTGIRGTRGYVAPEWFKNVGI 691
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPR 1136
DV+SFGV L EL+ + + + + L A R+ L++ +
Sbjct 692 TAKVDVYSFGVILLELICCRQNVEMEAAEEEQSILTYWANDCYRCGRVDLLVDGDDEAKL 751
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
K + C + E + RP+ + +L
Sbjct 752 NIKKVERFVAVALWCLQEEPTMRPSILKVTQMLD 785
Score = 206 bits (524), Expect = 1e-53, Method: Composition-based stats.
Identities = 59/318 (19%), Positives = 115/318 (36%), Gaps = 59/318 (19%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L L S+ +++ LG G VY+G+L+ E
Sbjct 499 LPLKAFSYAELEKATDGFKEVLGTGASGIVYKGQLQDEL--------------------- 537
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ +K +D H+ F + + H +L + G C G E ++V E++ +G
Sbjct 538 --GTYIAVKKIDKIQHETEKEFAVEVQTIGRTYHKNLVRMLGFCNEGTERLLVYEFMVNG 595
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEG 750
L+ +L + + ++ +A +A L YL + ++H ++ +NILL
Sbjct 596 SLNRFLFSGVRPL-WSLRVQLALGVARGLLYLHEECSTQIIHCDIKPQNILLD------- 647
Query 751 TSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ K+SD G+ + + + ++APE ++ +D + FG LL
Sbjct 648 DNFIAKISDFGLAKLLRTNQTQTYTGIRGTRGYVAPEWFKN--VGITAKVDVYSFGVILL 705
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQH------------------RLPEPSCPQLATLTSQ 847
E+ + + E+ + +L + +
Sbjct 706 ELICCRQNVEMEAAEEEQSILTYWANDCYRCGRVDLLVDGDDEAKLNIKKVERFVAVALW 765
Query 848 CLTYEPTQRPSFRTILRD 865
CL EPT RPS + +
Sbjct 766 CLQEEPTMRPSILKVTQM 783
>sp|Q25AG2|LERK4_ORYSI G-type lectin S-receptor-like serine/threonine-protein
kinase LECRK4 OS=Oryza sativa subsp. indica
OX=39946 GN=LECRK4 PE=3 SV=1
Length=804
Score = 222 bits (565), Expect = 6e-59, Method: Composition-based stats.
Identities = 66/274 (24%), Positives = 112/274 (41%), Gaps = 14/274 (5%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G G V D G +AVK + + + E+ + YH+++++
Sbjct 520 LGTGASGIVYKGQLQ---DELGTYIAVKKIDKIQHETEKE-FAVEVQTIGRTYHKNLVRM 575
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH---AQH 1018
G C + E+ LV E++ GSL +L + + A + G+ YLH +
Sbjct 576 LGFCNEGTER--LLVYEFMVNGSLNRFLFSGVRPLWSLRVQLALGVARGLLYLHEECSTQ 633
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IH D+ +N+LLD++ + KI DFGLAK + + + APE K
Sbjct 634 IIHCDIKPQNILLDDNFIAKISDFGLAKLLRTNQT--QTYTGIRGTRGYVAPEWFKNVGI 691
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPR 1136
DV+SFGV L EL+ + + + + L A R+ L++ +
Sbjct 692 TAKVDVYSFGVILLELICCRQNVEMEAAEEEQSILTYWANDCYRCGRVDLLVDGDDEAKL 751
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
K + C + E + RP+ + +L
Sbjct 752 NIKKVERFVAVALWCLQEEPTMRPSILKVTQMLD 785
Score = 206 bits (524), Expect = 1e-53, Method: Composition-based stats.
Identities = 59/318 (19%), Positives = 115/318 (36%), Gaps = 59/318 (19%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
L L S+ +++ LG G VY+G+L+ E
Sbjct 499 LPLKAFSYAELEKATDGFKEVLGTGASGIVYKGQLQDEL--------------------- 537
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+ +K +D H+ F + + H +L + G C G E ++V E++ +G
Sbjct 538 --GTYIAVKKIDKIQHETEKEFAVEVQTIGRTYHKNLVRMLGFCNEGTERLLVYEFMVNG 595
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEG 750
L+ +L + + ++ +A +A L YL + ++H ++ +NILL
Sbjct 596 SLNRFLFSGVRPL-WSLRVQLALGVARGLLYLHEECSTQIIHCDIKPQNILLD------- 647
Query 751 TSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ K+SD G+ + + + ++APE ++ +D + FG LL
Sbjct 648 DNFIAKISDFGLAKLLRTNQTQTYTGIRGTRGYVAPEWFKN--VGITAKVDVYSFGVILL 705
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQH------------------RLPEPSCPQLATLTSQ 847
E+ + + E+ + +L + +
Sbjct 706 ELICCRQNVEMEAAEEEQSILTYWANDCYRCGRVDLLVDGDDEAKLNIKKVERFVAVALW 765
Query 848 CLTYEPTQRPSFRTILRD 865
CL EPT RPS + +
Sbjct 766 CLQEEPTMRPSILKVTQM 783
>sp|Q9C823|Y1523_ARATH C-type lectin receptor-like tyrosine-protein
kinase At1g52310 OS=Arabidopsis thaliana OX=3702 GN=At1g52310
PE=2 SV=1
Length=552
Score = 216 bits (551), Expect = 6e-59, Method: Composition-based stats.
Identities = 73/264 (28%), Positives = 120/264 (45%), Gaps = 15/264 (6%)
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
G VAVK LK Q + + EI LYH +++ KGCC D GE+ +V E++
Sbjct 288 SDGTKVAVKRLKR-SSFQRKKEFYSEIRRAAKLYHPNVVAIKGCCYDHGER--FIVYEFI 344
Query 982 PLGSLRDYLPR-----HSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDN 1033
G L +L S+ L A + +G+A+LH + +HRD+ A NVLLD
Sbjct 345 ASGPLDRWLHHVPRGGRSLDWNMRLNIATTLAQGIAFLHDKVKPQVVHRDIRASNVLLDE 404
Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093
+ + GL+K VP R + APE + + SDV+SFGV L E
Sbjct 405 EFGAHLMGVGLSKFVPWEVMQERT-VMAGGTYGYLAPEYVYRNELTTKSDVYSFGVLLLE 463
Query 1094 LLTHCDSSQSPPTK--FLELIGIAQGQMTVLRLTELLERGERLPRPDKC-PCEVYHLMKN 1150
+++ +Q+ + + + A + R E+L+ P+ C +V L+ +
Sbjct 464 IVSGRRPTQAVNSSVGWQSIFEWATPLVQANRWLEILDPVITCGLPEACVVQKVVDLVYS 523
Query 1151 CWETEASFRPTFENLIPILKTVHE 1174
C + S RP +++ L+ + +
Sbjct 524 CTQNVPSMRPRMSHVVHQLQQLVQ 547
Score = 172 bits (436), Expect = 4e-44, Method: Composition-based stats.
Identities = 58/263 (22%), Positives = 98/263 (37%), Gaps = 32/263 (12%)
Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+V +K L S FY +++ H ++ + G C E +V E++ GPLD
Sbjct 291 TKVAVKRLKRSSFQRKKEFYSEIRRAAKLYHPNVVAIKGCCYDHGERFIVYEFIASGPLD 350
Query 697 VWLRR-ERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEG 750
WL RG + W ++ +A LA +++L +K +VH ++ N+LL A
Sbjct 351 RWLHHVPRGGRSLDWNMRLNIATTLAQGIAFLHDKVKPQVVHRDIRASNVLLDEEFGAHL 410
Query 751 TSPFIKLSDPGVGLGALSREERV--ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ LS V + + +LAPE + N L+T D + FG LLEI
Sbjct 411 M--GVGLSKF-VPWEVMQERTVMAGGTYGYLAPEYV--YRNELTTKSDVYSFGVLLLEIV 465
Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPE-------------------PSCPQLATLTSQCL 849
S + ++ L + ++ L C
Sbjct 466 SGRRPTQAVNSSVGWQSIFEWATPLVQANRWLEILDPVITCGLPEACVVQKVVDLVYSCT 525
Query 850 TYEPTQRPSFRTILRDLTRLQPH 872
P+ RP ++ L +L
Sbjct 526 QNVPSMRPRMSHVVHQLQQLVQP 548
>sp|P06244|KAPA_YEAST cAMP-dependent protein kinase type 1 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=TPK1 PE=1 SV=3
Length=397
Score = 211 bits (538), Expect = 6e-59, Method: Composition-based stats.
Identities = 70/324 (22%), Positives = 120/324 (37%), Gaps = 45/324 (14%)
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919
T + + + + + + +R LG G FG+V L
Sbjct 50 ETQEKPKQPHVTYYNEEQYKQFIAQARVTSGKYSLQDFQILRTLGTGSFGRVHLI----R 105
Query 920 NDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLV 977
+ G A+K LK + + E +L + H II+ G +D + + ++
Sbjct 106 SRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDA--QQIFMI 163
Query 978 MEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036
M+Y+ G L L + +A ++C + YLH++ I+RDL N+LLD +
Sbjct 164 MDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGH 223
Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096
+KI DFG AK VP+ V + APE + + + D WSFG+ +YE+L
Sbjct 224 IKITDFGFAKYVPD------VTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLA 277
Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156
T+ ++L R P +V L+ +
Sbjct 278 GYTPF--------------YDSNTMKTYEKILNAELRF--PPFFNEDVKDLLSRLITRDL 321
Query 1157 SFR--------------PTFENLI 1166
S R P F+ ++
Sbjct 322 SQRLGNLQNGTEDVKNHPWFKEVV 345
Score = 177 bits (449), Expect = 4e-47, Method: Composition-based stats.
Identities = 58/322 (18%), Positives = 113/322 (35%), Gaps = 41/322 (13%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
++ L LG G+ V+ R R G + +E+ V LK ++
Sbjct 85 QDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVL-------------KKEIVVRLKQVEH 131
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
++ + ++S V+H + + G + M+ +Y+E G L LR+ +
Sbjct 132 TN--------DERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQ-RF 182
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
P A ++ AL YL +K++++ ++ NILL + G IK++D G
Sbjct 183 PNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNG-------HIKITDFGFAKYV 235
Query 767 LSREER-VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
++APE + + ++D W FG + E+ S + E
Sbjct 236 PDVTYTLCGTPDYIAPEVVST--KPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEK 293
Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885
+ R P + L S+ +T + + + L LQ
Sbjct 294 ILNAELRFPPFFNEDVKDLLSRLITRD---------LSQRLGNLQNGTEDVKNHPWFKEV 344
Query 886 ASDPTVFHKRYLKKIRDLGEGH 907
+ + + +G
Sbjct 345 VWEKLLSRNIETPYEPPIQQGQ 366
>sp|Q8BWQ5|DCLK3_MOUSE Serine/threonine-protein kinase DCLK3 OS=Mus
musculus OX=10090 GN=Dclk3 PE=1 SV=2
Length=790
Score = 221 bits (564), Expect = 6e-59, Method: Composition-based stats.
Identities = 75/324 (23%), Positives = 127/324 (39%), Gaps = 29/324 (9%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
+P R ++ R + + P + +++ +G+G+F
Sbjct 467 EKKPGGLGERRAPEKESKRKLEEKRPERPSGRKPRPKGIISADVEKHYDIGGVIGDGNFA 526
Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
V + + T + A+K + EI I+++L H +I+K E +
Sbjct 527 TVK----ECRHRETKQAYAMKMIDKSQLKGKEDIVDSEILIIQSLSHPNIVKLHEVYETE 582
Query 970 GEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARN 1028
E + L+MEYV G L D + + + + +C+ + ++H ++ +HRD+ N
Sbjct 583 AE--IYLIMEYVQGGDLFDAIVENVKFPEPEAAVMITDLCKALVHMHDKNIVHRDVKPEN 640
Query 1029 VLL----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084
+L+ D +K+ DFGLAK V R + APE L E + D+
Sbjct 641 LLVQRNEDKSITLKLADFGLAKYV------VRPIFTVCGTPTYVAPEILSEKGYGLEVDM 694
Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ-GQMTVLRLTELLERGERLPRPDKCPCE 1143
W+ GV LY LL +SP EL I Q GQ L P D
Sbjct 695 WAAGVILYILLCGFPPFRSPERDQDELFNIIQVGQFEFLS-----------PYWDNISDA 743
Query 1144 VYHLMKNCWETEASFRPTFENLIP 1167
L++N E + R T E ++
Sbjct 744 AKDLVRNLLEVDPKKRYTAEQVLQ 767
Score = 166 bits (421), Expect = 5e-41, Method: Composition-based stats.
Identities = 66/324 (20%), Positives = 109/324 (34%), Gaps = 41/324 (13%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
P+ L R R S R + V++ +G G V E
Sbjct 479 PEKESKRKLEEKRPERPSGRKPRPKGIISADVEK-HYDIGGVIGDGNFATVKE------- 530
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE-TASLMSQVSHTHLA 671
R R + +K++D S + ++ +SH ++
Sbjct 531 -----------------CRHRETKQAYAMKMIDKSQLKGKEDIVDSEILIIQSLSHPNIV 573
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
+H V E ++ EYV+ G L + E P V+ L AL ++ +KN+V
Sbjct 574 KLHEVYETEAEIYLIMEYVQGGDLFDAI-VENVKFPEPEAAVMITDLCKALVHMHDKNIV 632
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-EERVERIPWLAPECLPGGANS 790
H +V N+L+ R E S +KL+D G+ + ++APE L
Sbjct 633 HRDVKPENLLVQRN---EDKSITLKLADFGLAKYVVRPIFTVCGTPTYVAPEILSE--KG 687
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-------HRLPEPSCPQLAT 843
+D W G L I G P +S + E F Q +
Sbjct 688 YGLEVDMWAAGVILY-ILLCGFPPFRSPERDQDELFNIIQVGQFEFLSPYWDNISDAAKD 746
Query 844 LTSQCLTYEPTQRPSFRTILRDLT 867
L L +P +R + +L+
Sbjct 747 LVRNLLEVDPKKRYTAEQVLQHPW 770
>sp|A1IVT7|HOG1_BOTFB Mitogen-activated protein kinase hog1 OS=Botryotinia
fuckeliana (strain B05.10) OX=332648 GN=hog1 PE=1
SV=1
Length=354
Score = 210 bits (535), Expect = 6e-59, Method: Composition-based stats.
Identities = 68/281 (24%), Positives = 107/281 (38%), Gaps = 29/281 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V ++ TG VAVK + K P +E+ +L+ L HE++
Sbjct 24 QPVGMGAFGLVC----SAKDNLTGSNVAVKKIMKPFSTPVLSKRTYRELKLLKHLKHENV 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
DVWS G E+L + + EL+G + LR +
Sbjct 192 DVEVDVWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIHTIASENTLRFVQ 251
Query 1127 LLERGERLPRPDK---CPCEVYHLMKNCWETEASFRPTFEN 1164
L + ER P K L++ + R
Sbjct 252 SLPKRERQPLASKFTQADPLAIDLLEKMLVFDPRARIKAAE 292
Score = 132 bits (331), Expect = 5e-32, Method: Composition-based stats.
Identities = 40/252 (16%), Positives = 81/252 (32%), Gaps = 21/252 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E D + M + +D V +K ++ P ++ Y
Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSAKDNLTGSNVAVKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLKHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
+ APE + +D W G E+ +G+ + F L
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDVWSAGCIFAEML-EGKPLFPGKDH--VNQFSIITELLGT 232
Query 836 PSCPQLATLTSQ 847
P + T+ S+
Sbjct 233 PPDDVIHTIASE 244
>sp|Q8W4S5|Y5371_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At5g63710 OS=Arabidopsis thaliana OX=3702
GN=At5g63710 PE=1 SV=1
Length=614
Score = 218 bits (554), Expect = 6e-59, Method: Composition-based stats.
Identities = 71/279 (25%), Positives = 116/279 (42%), Gaps = 21/279 (8%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FGKV VAVK L P + +++EI ++ H+++++
Sbjct 295 IGQGGFGKVYRGLL-----PDKTKVAVKRLADYFSPGGEAAFQREIQLISVAVHKNLLRL 349
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMAYLHAQ 1017
G C E+ LV Y+ S+ L + A G+ YLH
Sbjct 350 IGFCTTSSER--ILVYPYMENLSVAYRLRDLKAGEEGLDWPTRKRVAFGSAHGLEYLHEH 407
Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
IHRDL A N+LLDN+ +GDFGLAK V + V + APE L
Sbjct 408 CNPKIIHRDLKAANILLDNNFEPVLGDFGLAKLVDTSLTH--VTTQVRGTMGHIAPEYLC 465
Query 1075 EYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
K +DV+ +G+TL EL+T D S+ + + L+ + + RL ++++
Sbjct 466 TGKSSEKTDVFGYGITLLELVTGQRAIDFSRLEEEENILLLDHIKKLLREQRLRDIVDSN 525
Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
K + + C + RP ++ +L+
Sbjct 526 LT-TYDSKEVETIVQVALLCTQGSPEDRPAMSEVVKMLQ 563
Score = 180 bits (456), Expect = 4e-46, Method: Composition-based stats.
Identities = 68/323 (21%), Positives = 106/323 (33%), Gaps = 66/323 (20%)
Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L + S + + + +GQG VY G L
Sbjct 273 QLKRFSLREIQLATDSFNESNLIGQGGFGKVYRGLL------------------------ 308
Query 633 RGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
+ +V +K L D AF L+S H +L + G C E I+V Y+E
Sbjct 309 -PDKTKVAVKRLADYFSPGGEAAFQREIQLISVAVHKNLLRLIGFCTTSSERILVYPYME 367
Query 692 HGPLDVWLRRERG---HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745
+ + LR + + + VA A L YL ++H ++ NILL
Sbjct 368 NLSVAYRLRDLKAGEEGLDWPTRKRVAFGSAHGLEYLHEHCNPKIIHRDLKAANILLDNN 427
Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800
L D G+ + V + +APE L G + S D +G+
Sbjct 428 FEPV-------LGDFGLAKLVDTSLTHVTTQVRGTMGHIAPEYLCTGKS--SEKTDVFGY 478
Query 801 GATLLEICFDGEAPLQSR-------SPSEKEHFYQRQHRLPEPSCPQLAT---------- 843
G TLLE+ A SR + R+ RL + L T
Sbjct 479 GITLLELVTGQRAIDFSRLEEEENILLLDHIKKLLREQRLRDIVDSNLTTYDSKEVETIV 538
Query 844 -LTSQCLTYEPTQRPSFRTILRD 865
+ C P RP+ +++
Sbjct 539 QVALLCTQGSPEDRPAMSEVVKM 561
>sp|Q66HE5|NUAK2_RAT NUAK family SNF1-like kinase 2 OS=Rattus
norvegicus OX=10116 GN=Nuak2 PE=1 SV=1
Length=630
Score = 218 bits (555), Expect = 6e-59, Method: Composition-based stats.
Identities = 68/291 (23%), Positives = 114/291 (39%), Gaps = 32/291 (11%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
+ + + LG+G +GKV + +G +VA+K+++ D
Sbjct 39 MKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKAR-----ESSGRLVAIKSIRKDKIK 93
Query 939 QHRS--GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSI 995
+ ++EI+I+ +L H HII E+ + + +VMEY G L DY+ R +
Sbjct 94 DEQDLLHIRREIEIMSSLNHPHIIAIHEVFENSSK--IVIVMEYASRGDLYDYISERPRL 151
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
F +QI + Y H +HRDL N+LLD +KI DFGL+ +G
Sbjct 152 NERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDASGNIKIADFGLSNLYHKG---- 207
Query 1056 RVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+ + + +PE + + D WS GV LY L+ K L
Sbjct 208 KFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTL----- 262
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ ++ R P P + L++ R T E++
Sbjct 263 ---------VKQISSGAYREPC---KPSDACGLIRWLLMVNPIRRATLEDV 301
Score = 173 bits (438), Expect = 8e-44, Method: Composition-based stats.
Identities = 57/320 (18%), Positives = 94/320 (29%), Gaps = 45/320 (14%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEIT----QLSHLGQGTRTNVYEGRLRVEGS 613
S + SP+ L Q + + L LG+GT V + R
Sbjct 22 ESARPLADRLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKAR------ 75
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFY---ETASLMSQVSHTHL 670
V +K + +MS ++H H+
Sbjct 76 -------------------ESSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHI 116
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730
+H V + ++V EY G L ++ ER + +Q+ SAL Y +
Sbjct 117 IAIHEVFENSSKIVIVMEYASRGDLYDYI-SERPRLNERDARHFFRQIVSALHYCHQNGI 175
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGG 787
VH ++ NILL S IK++D G+ + + +PE + G
Sbjct 176 VHRDLKLENILLD-------ASGNIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGK 228
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ 847
+ +D W G L I G P + L
Sbjct 229 PY-VGPEVDSWSLGVLLY-ILVHGTMPFDGQDHKTLVKQISSGAYREPCKPSDACGLIRW 286
Query 848 CLTYEPTQRPSFRTILRDLT 867
L P +R + +
Sbjct 287 LLMVNPIRRATLEDVASHWW 306
>sp|P27466|KCC1_YEAST Calcium/calmodulin-dependent protein kinase
I OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=CMK1 PE=1 SV=2
Length=446
Score = 213 bits (542), Expect = 6e-59, Method: Composition-based stats.
Identities = 67/292 (23%), Positives = 113/292 (39%), Gaps = 26/292 (9%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR- 941
+ + +K+ + LG G FG V N TGE VAVK L ++
Sbjct 23 MAHVQPASYVNKKKYVFGKTLGAGTFGVVR----QAKNTETGEDVAVKILIKKALKGNKV 78
Query 942 --SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLA 998
E+DIL+ L+H +I+ +K E + + ++ + G L D L +
Sbjct 79 QLEALYDELDILQRLHHPNIVAFKDWFESKDK--FYIITQLAKGGELFDRILKKGKFTEE 136
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYY 1055
+ +I + Y+H+Q+ +HRDL N+L ++ + + DFG+AK + E
Sbjct 137 DAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELL 196
Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115
+ + APE L + D+WS GV Y LL + ++ + L
Sbjct 197 YK---PAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDF-LDECT 252
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
G+ V P D + + + S RPT L+
Sbjct 253 TGEYPV---------KFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLE 295
Score = 157 bits (398), Expect = 7e-40, Method: Composition-based stats.
Identities = 48/299 (16%), Positives = 110/299 (37%), Gaps = 43/299 (14%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL-- 641
V++K+ LG GT V + + + G+++ V +
Sbjct 32 VNKKKYVFGKTLGAGTFGVVRQAK----------------------NTETGEDVAVKILI 69
Query 642 -KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
K L + + A Y+ ++ ++ H ++ + ++T+ + G L +
Sbjct 70 KKALKGNKVQL-EALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRIL 128
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ +G + + ++ SA+ Y+ ++N+VH ++ N+L + + + ++D
Sbjct 129 K-KGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLL----YIDKSDESPLVVADF 183
Query 761 GVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
G+ S EE + ++APE L + D W G + A
Sbjct 184 GIAKRLKSDEELLYKPAGSLGYVAPEVLTQ--DGHGKPCDIWSIGVITYTLLCGYSAFRA 241
Query 817 SRSPSEKE-----HFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
R + + + HR + + + L +P++RP+ +L D +
Sbjct 242 ERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWII 300
>sp|Q6C3J2|IPL1_YARLI Spindle assembly checkpoint kinase OS=Yarrowia
lipolytica (strain CLIB 122 / E 150) OX=284591 GN=IPL1
PE=3 SV=1
Length=371
Score = 211 bits (536), Expect = 6e-59, Method: Composition-based stats.
Identities = 68/275 (25%), Positives = 116/275 (42%), Gaps = 36/275 (13%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960
LG+G FGKV L + TG + A+K ++ + +++E++I L H +++
Sbjct 105 LGKGKFGKVYLV----KDKKTGFVSALKCMEKKELVEGNVEKQFRREVEIQSNLRHTNVL 160
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G D+ + L++EYV G L L + + Q+ E + YLH ++
Sbjct 161 RLFGHFHDKD--RVYLILEYVVHGELYKLLRNQKRFTESTASSYIYQMSEALLYLHGKNI 218
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ N+LL + +KI DFG + P R + + PE ++ +
Sbjct 219 IHRDIKPENILLHFNDTIKISDFGWSVHAPSNR-----RSTLCGTMDYLPPEIVQSRPYD 273
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
DVWS G+ +YE L + P Q T R+ +L R P
Sbjct 274 KNVDVWSLGILMYEFLCGAPPFEEPGG----------AQATYRRIVKLDLR-----IPPY 318
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+ L+K + + R F+ LK +H+
Sbjct 319 VSADAADLIKRMLTLDPAKR--FK-----LKDMHK 346
Score = 193 bits (491), Expect = 7e-53, Method: Composition-based stats.
Identities = 64/326 (20%), Positives = 114/326 (35%), Gaps = 36/326 (11%)
Query 549 RCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRL 608
R S + P + F + LG+G VY +
Sbjct 59 RPTNLTKTPASQVSRRSSYTTDPPSPLTGITGFRNYSLDDFEIGKALGKGKFGKVY--LV 116
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHT 668
+ + +G K ++ LV G ++ F + S + HT
Sbjct 117 KDKKTGFVSALKCMEKKELVEG-------------------NVEKQFRREVEIQSNLRHT 157
Query 669 HLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK 728
++ + G ++ EYV HG L LR ++ + Q++ AL YL K
Sbjct 158 NVLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQK-RFTESTASSYIYQMSEALLYLHGK 216
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--REERVERIPWLAPECLPG 786
N++H ++ NILL + IK+SD G + A S R + +L PE +
Sbjct 217 NIIHRDIKPENILL-------HFNDTIKISDFGWSVHAPSNRRSTLCGTMDYLPPEIVQ- 268
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--EHFYQRQHRLPEPSCPQLATL 844
+ +D W G + E G P + ++ + R+P A L
Sbjct 269 -SRPYDKNVDVWSLGILMYEFLC-GAPPFEEPGGAQATYRRIVKLDLRIPPYVSADAADL 326
Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ LT +P +R + + + ++
Sbjct 327 IKRMLTLDPAKRFKLKDMHKHPWIVR 352
>sp|G7JIK2|SUNN_MEDTR Leucine-rich repeat receptor-like kinase
protein SUNN OS=Medicago truncatula OX=3880 GN=SUNN PE=1 SV=2
Length=974
Score = 224 bits (570), Expect = 7e-59, Method: Composition-based stats.
Identities = 73/323 (23%), Positives = 126/323 (39%), Gaps = 21/323 (7%)
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920
+ + R + ++A + LK+ +G+G G V +
Sbjct 649 IVTLHMMRKRKRHMAKAWKLTAFQKLEFRAEEVVECLKEENIIGKGGAGIVYRG-----S 703
Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
G VA+K L ++ G+K EI+ L + H +I++ G ++ L+ EY
Sbjct 704 MANGTDVAIKRLVGQGSGRNDYGFKAEIETLGRIRHRNIMRLLGYVSNKDTN--LLLYEY 761
Query 981 VPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDND 1034
+P GSL ++L + A + +G+ YLH IHRD+ + N+LLD D
Sbjct 762 MPNGSLGEWLHGAKGCHLSWEMRYKIAVEAAKGLCYLHHDCSPLIIHRDVKSNNILLDAD 821
Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094
+ DFGLAK + + + S + APE K SDV+SFGV L EL
Sbjct 822 FEAHVADFGLAKFLYDPGASQSMSSIAGS-YGYIAPEYAYTLKVDEKSDVYSFGVVLLEL 880
Query 1095 LTHCDSSQSPPTKFLELIGIAQG------QMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148
+ ++++G Q + L + P ++++
Sbjct 881 IIGRKPVGE-FGDGVDIVGWINKTELELYQPSDKALVSAVVDPRLNGYPLTSVIYMFNIA 939
Query 1149 KNCWETEASFRPTFENLIPILKT 1171
C + RPT ++ +L
Sbjct 940 MMCVKEMGPARPTMREVVHMLTN 962
Score = 188 bits (478), Expect = 2e-47, Method: Composition-based stats.
Identities = 53/326 (16%), Positives = 92/326 (28%), Gaps = 47/326 (14%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPS 647
+ + + +G+G VY G V +K L
Sbjct 685 LKEENIIGKGGAGIVYRG-------------------------SMANGTDVAIKRLVGQG 719
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HV 706
F + ++ H ++ + G N+++ EY+ +G L WL +G H+
Sbjct 720 SGRNDYGFKAEIETLGRIRHRNIMRLLGYVSNKDTNLLLYEYMPNGSLGEWLHGAKGCHL 779
Query 707 PMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ +A + A L YL + ++H +V NILL ++D G+
Sbjct 780 SWEMRYKIAVEAAKGLCYLHHDCSPLIIHRDVKSNNILLD-------ADFEAHVADFGLA 832
Query 764 LGAL------SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
S ++APE + D + FG LLE+ G P
Sbjct 833 KFLYDPGASQSMSSIAGSYGYIAPEYA--YTLKVDEKSDVYSFGVVLLELII-GRKP-VG 888
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
+ E P L S + P I +
Sbjct 889 EFGDGVDIVGWINKTELELYQPSDKALVSAVVDPRLNGYPLTSVIYMFNIAMMCVKEMGP 948
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDL 903
T + +L
Sbjct 949 ARPTMREVVHMLTNPPHSTSHNLINL 974
>sp|F4IS56|ILK1_ARATH Integrin-linked protein kinase 1 OS=Arabidopsis
thaliana OX=3702 GN=ILK1 PE=1 SV=1
Length=479
Score = 214 bits (545), Expect = 7e-59, Method: Composition-based stats.
Identities = 72/261 (28%), Positives = 115/261 (44%), Gaps = 22/261 (8%)
Query 921 DGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978
G V+VK L D P+ + ++ E+ +L + H ++I++ G + +V+
Sbjct 213 KWNGTRVSVKILDKDSYSDPERINAFRHELTLLEKVRHPNVIQFVGAVTQN--IPMMIVV 270
Query 979 EYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDND 1034
EY P G L YL + + ++ L FA I GM YLH IH DL +N+LLD
Sbjct 271 EYNPKGDLSVYLQKKGRLSPSKALRFALDIARGMNYLHECKPDPIIHCDLKPKNILLDRG 330
Query 1035 RLVKIGDFG---LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091
+KI FG L+K + + + D ++ APE K+ F D SFGV L
Sbjct 331 GQLKISGFGMIRLSKISQDKAKVANHKAHIDLSNYYIAPEVYKDEIFDLRVDAHSFGVIL 390
Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
YE+ P + + + +G+ V + + P ++ L++ C
Sbjct 391 YEITEGVPVFHPRPPEEVARMMCLEGKRPVFK-----------TKSRSYPPDIKELIEKC 439
Query 1152 WETEASFRPTFENLIPILKTV 1172
W EA RPTF +I L +
Sbjct 440 WHPEAGIRPTFSEIIIRLDKI 460
Score = 173 bits (438), Expect = 7e-45, Method: Composition-based stats.
Identities = 58/298 (19%), Positives = 105/298 (35%), Gaps = 35/298 (12%)
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH---DIALAFYETASLMSQVSHTH 669
+ + + G RV +K+LD + + AF +L+ +V H +
Sbjct 195 EVQVRKSDGISKGAYQVAKWNGT--RVSVKILDKDSYSDPERINAFRHELTLLEKVRHPN 252
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN-- 727
+ G + ++V EY G L V+L++ +G + + + A +A ++YL
Sbjct 253 VIQFVGAVTQNIPMMIVVEYNPKGDLSVYLQK-KGRLSPSKALRFALDIARGMNYLHECK 311
Query 728 -KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGALSREERVERI---- 776
++H ++ +NILL R G +K+S G+ I
Sbjct 312 PDPIIHCDLKPKNILLDRGGQ-------LKISGFGMIRLSKISQDKAKVANHKAHIDLSN 364
Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP-- 834
++APE +D FG L EI +G R P E + + P
Sbjct 365 YYIAPEVYKDEI--FDLRVDAHSFGVILYEI-TEGVPVFHPRPPEEVARMMCLEGKRPVF 421
Query 835 ----EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASD 888
P + L +C E RP+F I+ L ++ + +
Sbjct 422 KTKSRSYPPDIKELIEKCWHPEAGIRPTFSEIIIRLDKIVANCSKQGWWKDTFKFPWK 479
>sp|Q6XAT2|ERL2_ARATH LRR receptor-like serine/threonine-protein
kinase ERL2 OS=Arabidopsis thaliana OX=3702 GN=ERL2 PE=1
SV=1
Length=967
Score = 224 bits (570), Expect = 7e-59, Method: Composition-based stats.
Identities = 67/339 (20%), Positives = 128/339 (38%), Gaps = 20/339 (6%)
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
TL + + + + +L ++ D + L +
Sbjct 595 FITLICMIFIAVYKSKQQKPVLKGSSKQPEGSTKLVILHMDMAIHTFDDIMRVTENLDEK 654
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G G V T +A+K + + P + ++ E++ + ++ H +I+
Sbjct 655 YIIGYGASSTVYKCTSK-----TSRPIAIKRI-YNQYPSNFREFETELETIGSIRHRNIV 708
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016
G L +Y+ GSL D L + + L A +G+AYLH
Sbjct 709 SLHGYALSPFGN--LLFYDYMENGSLWDLLHGPGKKVKLDWETRLKIAVGAAQGLAYLHH 766
Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
IHRD+ + N+LLD + ++ DFG+AK++P Y G + + PE
Sbjct 767 DCTPRIIHRDIKSSNILLDGNFEARLSDFGIAKSIPATKTYASTYVLG--TIGYIDPEYA 824
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ + SD++SFG+ L ELLT + + ++I TV+ +
Sbjct 825 RTSRLNEKSDIYSFGIVLLELLTGKKAVDN-EANLHQMILSKADDNTVMEAVDAEVSVTC 883
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ + + L C + RPT + + +L ++
Sbjct 884 MD--SGHIKKTFQLALLCTKRNPLERPTMQEVSRVLLSL 920
Score = 184 bits (466), Expect = 4e-46, Method: Composition-based stats.
Identities = 51/341 (15%), Positives = 117/341 (34%), Gaps = 67/341 (20%)
Query 555 PGETSNLIIMRGARASPR--------TLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNVY 604
+++G+ P ++++ +F + + + + + +G G + VY
Sbjct 607 YKSKQQKPVLKGSSKQPEGSTKLVILHMDMAIHTFDDIMRVTENLDEKYIIGYGASSTVY 666
Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664
+ + + +K + + F +
Sbjct 667 KCTSK-------------------------TSRPIAIKRIYNQYPSNFREFETELETIGS 701
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASAL 722
+ H ++ +HG + N++ +Y+E+G L L V + W ++ +A A L
Sbjct 702 IRHRNIVSLHGYALSPFGNLLFYDYMENGSLWDLLHGPGKKVKLDWETRLKIAVGAAQGL 761
Query 723 SYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----E 774
+YL + ++H ++ NILL + +LSD G+ + +
Sbjct 762 AYLHHDCTPRIIHRDIKSSNILLD-------GNFEARLSDFGIAKSIPATKTYASTYVLG 814
Query 775 RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834
I ++ PE + L+ D + FG LLE+ +A + + + +
Sbjct 815 TIGYIDPEYART--SRLNEKSDIYSFGIVLLELLTGKKAVDNEANLHQMILSKADDNTVM 872
Query 835 EPSCPQLA-------------TLTSQCLTYEPTQRPSFRTI 862
E +++ L C P +RP+ + +
Sbjct 873 EAVDAEVSVTCMDSGHIKKTFQLALLCTKRNPLERPTMQEV 913
>sp|Q66HE7|CDKL1_RAT Cyclin-dependent kinase-like 1 OS=Rattus
norvegicus OX=10116 GN=Cdkl1 PE=2 SV=1
Length=352
Score = 210 bits (534), Expect = 7e-59, Method: Composition-based stats.
Identities = 62/293 (21%), Positives = 119/293 (41%), Gaps = 29/293 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960
+GEG +G V + N TG++VA+K L+ + P + +EI +L+ L H +++
Sbjct 9 KIGEGSYGVV----FKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLV 64
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ + L LV EY L + + + + Q + + + H +
Sbjct 65 SLLEVFRRK--RRLHLVFEYCHHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKHNC 122
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEYKF 1078
IHRD+ N+L+ ++K+ DFG A+ + +YY D + ++ +PE L + ++
Sbjct 123 IHRDVKPENILITKHSVIKLCDFGFARLLTGPGDYY---TDYVATRWYRSPELLVGDTQY 179
Query 1079 YYASDVWSFGVTLYELLTHCD-----SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
DVW+ G ELL+ S + +G + + G +
Sbjct 180 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVK 239
Query 1134 LPRPD----------KCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHE 1174
+P P+ +K C + + R T E L+ P ++ +
Sbjct 240 IPDPEDMETLELKFPNISYSALGFLKGCLHMDPAERLTCEQLLQHPYFDSIRD 292
Score = 154 bits (389), Expect = 1e-39, Method: Composition-based stats.
Identities = 49/250 (20%), Positives = 86/250 (34%), Gaps = 40/250 (16%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ ++ +G+G+ V++ R R G V +K
Sbjct 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQ------------------------IVAIKRFL 36
Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ D I ++ Q+ H +L + V R +V EY H L R +R
Sbjct 37 ETEDDPVIKKIALREIRMLKQLKHPNLVSLLEVFRRKRRLHLVFEYCHHTVLHELDRYQR 96
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
G VP + Q A+++ N +H +V NIL+ + IKL D G
Sbjct 97 G-VPEPLVKNITWQTLQAVNFCHKHNCIHRDVKPENILITK-------HSVIKLCDFGFA 148
Query 764 LGAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ V + +PE L G +D W G E+ G +S
Sbjct 149 RLLTGPGDYYTDYVATRWYRSPELLV-GDTQYGPPVDVWAIGCVFAELLS-GVPLWPGKS 206
Query 820 PSEKEHFYQR 829
++ + ++
Sbjct 207 DVDQLYLIRK 216
>sp|Q7RJG2|CDPK4_PLAYO Calcium-dependent protein kinase 4 OS=Plasmodium
yoelii yoelii OX=73239 GN=CDPK4 PE=3 SV=3
Length=528
Score = 215 bits (548), Expect = 8e-59, Method: Composition-based stats.
Identities = 69/288 (24%), Positives = 116/288 (40%), Gaps = 33/288 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960
LG+G FG+V L + TG A+K + + +E+++L+ L H +I+
Sbjct 76 LGKGSFGEVILS----KDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINIM 131
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
K ED LV + G L D + R +Q+ G+ Y+H +
Sbjct 132 KLYEFFEDNN--YYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNV 189
Query 1020 IHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRDL N+LL D ++KI DFGL+ EY + +D ++ AP+ L
Sbjct 190 VHRDLKPENILLETKNKEDMIIKIIDFGLSTHF----EYSKKMKDKIGTAYYIAPDVL-H 244
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ D+WS GV LY LL+ C + +L+ E + LP
Sbjct 245 GTYDEKCDIWSCGVILYILLSGCPPFNG------------SNEYDILKKVETGKYTFDLP 292
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183
+ K + L+K ++ R + + L+ + +V
Sbjct 293 QFKKISDKAKDLIKKMLMYTSAVRISARD---ALEHEWIRLMTSKDNV 337
Score = 157 bits (396), Expect = 4e-39, Method: Composition-based stats.
Identities = 64/409 (16%), Positives = 131/409 (32%), Gaps = 52/409 (13%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
+ S I+ S + + + V ++ + LG+G+ V
Sbjct 35 RSTSISKEIVKNSFNNSKLRPGMFIQNSNVVFNEQYKGIKILGKGSFGEV---------- 84
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA---LAFYETASLMSQVSHTHL 670
+ +D+ +KV+ H + L+ + H ++
Sbjct 85 --------------ILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINI 130
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730
++ +V++ G L + + + + +Q+ S ++Y+ N+
Sbjct 131 MKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVD-AARIIKQVLSGITYMHKNNV 189
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---WLAPECLPGG 787
VH ++ NILL IK+ D G+ ++ ++I ++AP+ L G
Sbjct 190 VHRDLKPENILL---ETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIAPDVLHG- 245
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR---LPEP--SCPQLA 842
+ D W G L I G P + + + LP+ +
Sbjct 246 --TYDEKCDIWSCGVILY-ILLSGCPPFNGSNEYDILKKVETGKYTFDLPQFKKISDKAK 302
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902
L + L Y R S R L + +V P S + + +K+
Sbjct 303 DLIKKMLMYTSAVRISARDALEHEWIRLMTSKDNVNIDIPSLELSITNIKQFQSTQKLAQ 362
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAV-KALKADCGPQHRSGWKQEIDI 950
+ + T D T E+ + K + + Q + E+ I
Sbjct 363 AAL-----LYMGSKLTTIDETKELTKIFKKMDKNGDGQLD---RNELII 403
>sp|C0LGW6|ERL1_ARATH LRR receptor-like serine/threonine-protein
kinase ERL1 OS=Arabidopsis thaliana OX=3702 GN=ERL1 PE=1
SV=1
Length=966
Score = 223 bits (569), Expect = 8e-59, Method: Composition-based stats.
Identities = 68/345 (20%), Positives = 133/345 (39%), Gaps = 24/345 (7%)
Query 838 CPQLATLTSQCLTYEPTQRPSF--RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895
C L +T C+ + + + + + + +L ++ D +
Sbjct 587 CIVLGVITLLCMIFLAVYKSMQQKKILQGSSKQAEGLTKLVILHMDMAIHTFDDIMRVTE 646
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
L + +G G V + +A+K L + P + ++ E++ + ++
Sbjct 647 NLNEKFIIGYGASSTVYKCALK-----SSRPIAIKRL-YNQYPHNLREFETELETIGSIR 700
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGM 1011
H +I+ G L +Y+ GSL D L + + L A +G+
Sbjct 701 HRNIVSLHGYALSPTGN--LLFYDYMENGSLWDLLHGSLKKVKLDWETRLKIAVGAAQGL 758
Query 1012 AYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
AYLH IHRD+ + N+LLD + + DFG+AK++P + G + +
Sbjct 759 AYLHHDCTPRIIHRDIKSSNILLDENFEAHLSDFGIAKSIPASKTHASTYVLG--TIGYI 816
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE + + SD++SFG+ L ELLT + + ++ A + E +
Sbjct 817 DPEYARTSRINEKSDIYSFGIVLLELLTGKKAVDNEANLHQLILSKADDNT----VMEAV 872
Query 1129 ERGERLPRPD-KCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+ + D + + L C + RPT + +L ++
Sbjct 873 DPEVTVTCMDLGHIRKTFQLALLCTKRNPLERPTMLEVSRVLLSL 917
Score = 187 bits (476), Expect = 3e-47, Method: Composition-based stats.
Identities = 50/300 (17%), Positives = 102/300 (34%), Gaps = 57/300 (19%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ + + +G G + VY+ L+ + +K L
Sbjct 645 TENLNEKFIIGYGASSTVYKCALKSSRP-------------------------IAIKRLY 679
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ F + + H ++ +HG + N++ +Y+E+G L L
Sbjct 680 NQYPHNLREFETELETIGSIRHRNIVSLHGYALSPTGNLLFYDYMENGSLWDLLHGSLKK 739
Query 706 VPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
V + W ++ +A A L+YL + ++H ++ NILL + LSD
Sbjct 740 VKLDWETRLKIAVGAAQGLAYLHHDCTPRIIHRDIKSSNILLDE-------NFEAHLSDF 792
Query 761 GVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ + + I ++ PE + ++ D + FG LLE+ +A
Sbjct 793 GIAKSIPASKTHASTYVLGTIGYIDPEYART--SRINEKSDIYSFGIVLLELLTGKKAVD 850
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQL-------------ATLTSQCLTYEPTQRPSFRTI 862
+ + + + E P++ L C P +RP+ +
Sbjct 851 NEANLHQLILSKADDNTVMEAVDPEVTVTCMDLGHIRKTFQLALLCTKRNPLERPTMLEV 910
>sp|P62345|CDPK4_PLABA Calcium-dependent protein kinase 4 OS=Plasmodium
berghei (strain Anka) OX=5823 GN=CDPK4 PE=1 SV=2
Length=528
Score = 215 bits (548), Expect = 8e-59, Method: Composition-based stats.
Identities = 69/288 (24%), Positives = 116/288 (40%), Gaps = 33/288 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960
LG+G FG+V L + TG A+K + + +E+++L+ L H +I+
Sbjct 76 LGKGSFGEVILS----KDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINIM 131
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
K ED LV + G L D + R +Q+ G+ Y+H +
Sbjct 132 KLYEFFEDNN--YYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNV 189
Query 1020 IHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRDL N+LL D ++KI DFGL+ EY + +D ++ AP+ L
Sbjct 190 VHRDLKPENILLETKNKEDMIIKIIDFGLSTHF----EYSKKMKDKIGTAYYIAPDVL-H 244
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ D+WS GV LY LL+ C + +L+ E + LP
Sbjct 245 GTYDEKCDIWSCGVILYILLSGCPPFNG------------SNEYDILKKVETGKYTFDLP 292
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183
+ K + L+K ++ R + + L+ + +V
Sbjct 293 QFKKISDKAKDLIKKMLMYTSAVRISARD---ALEHEWIRLMTSKDNV 337
Score = 157 bits (396), Expect = 5e-39, Method: Composition-based stats.
Identities = 64/409 (16%), Positives = 131/409 (32%), Gaps = 52/409 (13%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
+ S I+ S + + + V ++ + LG+G+ V
Sbjct 35 RSTSISKEIVKNSFNNSKLRPGMFIQNSNVVFNEQYKGIKILGKGSFGEV---------- 84
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA---LAFYETASLMSQVSHTHL 670
+ +D+ +KV+ H + L+ + H ++
Sbjct 85 --------------ILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINI 130
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730
++ +V++ G L + + + + +Q+ S ++Y+ N+
Sbjct 131 MKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVD-AARIIKQVLSGITYMHKNNV 189
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---WLAPECLPGG 787
VH ++ NILL IK+ D G+ ++ ++I ++AP+ L G
Sbjct 190 VHRDLKPENILL---ETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIAPDVLHG- 245
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR---LPEP--SCPQLA 842
+ D W G L I G P + + + LP+ +
Sbjct 246 --TYDEKCDIWSCGVILY-ILLSGCPPFNGSNEYDILKKVETGKYTFDLPQFKKISDKAK 302
Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902
L + L Y R S R L + +V P S + + +K+
Sbjct 303 DLIKKMLMYTSAVRISARDALEHEWIRLMTSKDNVNIDIPSLELSITNIKQFQSTQKLAQ 362
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAV-KALKADCGPQHRSGWKQEIDI 950
+ + T D T E+ + K + + Q + E+ I
Sbjct 363 AAL-----LYMGSKLTTIDETKELTKIFKKMDKNGDGQLD---RNELII 403
>sp|P53778|MK12_HUMAN Mitogen-activated protein kinase 12 OS=Homo
sapiens OX=9606 GN=MAPK12 PE=1 SV=3
Length=367
Score = 210 bits (535), Expect = 8e-59, Method: Composition-based stats.
Identities = 63/302 (21%), Positives = 123/302 (41%), Gaps = 36/302 (12%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLY 955
+ ++ +G G +G V + TG VA+K L + +E+ +L+ +
Sbjct 27 YRDLQPVGSGAYGAVC----SAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMR 82
Query 956 HEHIIKYKGCCEDQ----GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011
HE++I LVM ++ L + +G ++ Q+ +G+
Sbjct 83 HENVIGLLDVFTPDETLDDFTDFYLVMPFM-GTDLGKLMKHEKLGEDRIQFLVYQMLKGL 141
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
Y+HA IHRDL N+ ++ D +KI DFGLA+ Y V ++ APE
Sbjct 142 RYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVV------TRWYRAPE 195
Query 1072 CLKEY-KFYYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGI 1114
+ + ++ D+WS G + E++T + +PP +F++ +
Sbjct 196 VILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQS 255
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTV 1172
+ + + L E LE+ + +L++ +A R T + P +++
Sbjct 256 DEAKNYMKGLPE-LEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFESL 314
Query 1173 HE 1174
H+
Sbjct 315 HD 316
Score = 127 bits (318), Expect = 4e-30, Method: Composition-based stats.
Identities = 35/219 (16%), Positives = 71/219 (32%), Gaps = 20/219 (9%)
Query 632 DRGQELRVVLKVL-DPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPEN------ 683
D +V +K L P ++ A Y L+ + H ++ + V
Sbjct 46 DGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDF 105
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743
+V ++ L ++ E+ + + Q+ L Y+ ++H ++ N+
Sbjct 106 YLVMPFM-GTDLGKLMKHEK--LGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNL--- 159
Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL-APECLPGGANSLSTAMDKWGFGA 802
A +K+ D G+ A S W APE + + +D W G
Sbjct 160 ----AVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMR-YTQTVDIWSVGC 214
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL 841
+ E+ S + + + P +L
Sbjct 215 IMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRL 253
>sp|Q4WHP3|STE20_ASPFU Serine/threonine-protein kinase ste20 OS=Aspergillus
fumigatus (strain ATCC MYA-4609 / CBS 101355 /
FGSC A1100 / Af293) OX=330879 GN=ste20 PE=3 SV=2
Length=815
Score = 221 bits (564), Expect = 8e-59, Method: Composition-based stats.
Identities = 60/270 (22%), Positives = 113/270 (42%), Gaps = 23/270 (9%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+ +G+G G V Y GT VA+K + D P+ + EI +++ H
Sbjct 534 YYNLNKIGQGASGGV----YTAYQHGTNNCVAIKQMNLDLQPK-KELIINEILVMKDSKH 588
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016
++I+ + + L +VMEY+ GSL D + + + Q+ ++ G+ +LH+
Sbjct 589 KNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMTEGQIAAVCRETLNGLQHLHS 646
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ IHRD+ + N+LL D +K+ DFG + ++ R +W APE +
Sbjct 647 KGVIHRDIKSDNILLSLDGNIKLTDFGFCAQI---NDSQNKRNTMVGTPYWMAPEVVTRK 703
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
++ D+WS G+ E++ + + L IA ++ L R
Sbjct 704 EYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLIATNGTPTIKDEHNLSPVFR--- 759
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ HL + + R + +L+
Sbjct 760 ------DFLHLA---LKVDPEKRASAHDLL 780
Score = 179 bits (453), Expect = 7e-45, Method: Composition-based stats.
Identities = 64/351 (18%), Positives = 104/351 (30%), Gaps = 45/351 (13%)
Query 535 GCLLRAGDDCFSLRRCCLPQP-GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLS 593
G A D +L+ QP R + A L + K L+
Sbjct 479 GHSQHANDHTTALQSPQKAQPVPAARPRQRARQSNAVDVRARLLAICTPGDPTKLYYNLN 538
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
+GQG VY G V +K ++
Sbjct 539 KIGQGASGGVY------------------------TAYQHGTNNCVAIKQMNLDLQPKKE 574
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713
+M H ++ + G + +V EY+E G L + +
Sbjct 575 LIINEILVMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVV--TFNIMTEGQIAA 632
Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----R 769
V ++ + L +L +K ++H ++ NILL+ IKL+D G R
Sbjct 633 VCRETLNGLQHLHSKGVIHRDIKSDNILLS-------LDGNIKLTDFGFCAQINDSQNKR 685
Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829
V W+APE + +D W G +E+ +GE P + SP +
Sbjct 686 NTMVGTPYWMAPEVVT--RKEYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLIAT 742
Query 830 QHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
P L +P +R S +L L
Sbjct 743 NGTPTIKDEHNLSPVFRDFLHLALKVDPEKRASAHDLLMHPFMSLCSPLTH 793
>sp|Q59W62|GIN4_CANAL Serine/threonine-protein kinase GIN4 OS=Candida
albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=GIN4
PE=1 SV=1
Length=1349
Score = 226 bits (575), Expect = 9e-59, Method: Composition-based stats.
Identities = 81/308 (26%), Positives = 127/308 (41%), Gaps = 36/308 (12%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
PH+ ++ + S ++ K + LG G G+V L T+ TG+ AV
Sbjct 1 MPHSRQPSISSSIMSQSNHNHPQKIGPWKLGKTLGRGATGRVLL----ATHQTTGQKAAV 56
Query 930 KALKADCGPQHRSG---------WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
K + + ++EI I++ L H ++++ E K+L LV+EY
Sbjct 57 KVVSKSELQDEETEKNGDGLPYGIEREIIIMKLLTHPNVLRLYDVWE--TSKALYLVLEY 114
Query 981 VPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039
V G L D L R + + + + +QI G AY HA HRDL N+LLD+ VK+
Sbjct 115 VEGGELFDLLVERGPLPEVEAIKYFRQIILGTAYCHALGICHRDLKPENLLLDSQLNVKL 174
Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHC 1098
DFG+A G ++ E + APE + K+ ASDVWS GV L+ LLT
Sbjct 175 ADFGMAALESNG----KLLETSCGSPHYAAPEIVSGLKYHGAASDVWSCGVILFALLTGR 230
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
+ L ++ G D+ E L+ E +
Sbjct 231 LPFDDE---------------NIRNLLLKVQAGNFEMPVDEVSREARDLIARMLEVDPMR 275
Query 1159 RPTFENLI 1166
R + E ++
Sbjct 276 RISTEKIL 283
Score = 164 bits (415), Expect = 1e-39, Method: Composition-based stats.
Identities = 54/292 (18%), Positives = 92/292 (32%), Gaps = 49/292 (17%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
LG+G V + G + +KV+ S
Sbjct 29 KLGKTLGRGATGRVLLATHQTTGQ------------------------KAAVKVVSKSEL 64
Query 650 DIALA----------FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
+M ++H ++ ++ V +V EYVE G L L
Sbjct 65 QDEETEKNGDGLPYGIEREIIIMKLLTHPNVLRLYDVWETSKALYLVLEYVEGGELFDLL 124
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
ERG +P + +Q+ +Y + H ++ N+LL + +KL+D
Sbjct 125 -VERGPLPEVEAIKYFRQIILGTAYCHALGICHRDLKPENLLLD-------SQLNVKLAD 176
Query 760 PGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
G+ + E + APE + G A D W G L + G P
Sbjct 177 FGMAALESNGKLLETSCGSPHYAAPE-IVSGLKYHGAASDVWSCGVILFALL-TGRLPFD 234
Query 817 SRSPSE-KEHFYQRQHRLP-EPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
+ +P + + L ++ L +P +R S ILR
Sbjct 235 DENIRNLLLKVQAGNFEMPVDEVSREARDLIARMLEVDPMRRISTEKILRHP 286
>sp|Q9M0G7|MIK1_ARATH MDIS1-interacting receptor like kinase 1
OS=Arabidopsis thaliana OX=3702 GN=MIK1 PE=1 SV=1
Length=1013
Score = 224 bits (570), Expect = 9e-59, Method: Composition-based stats.
Identities = 68/301 (23%), Positives = 126/301 (42%), Gaps = 27/301 (9%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL---KADCGPQHRSGWKQEIDILR 952
+K+ +G G G V Y + ++AVK L AD + E+++L
Sbjct 698 CIKESNMIGMGATGIV----YKAEMSRSSTVLAVKKLWRSAADIEDGTTGDFVGEVNLLG 753
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQ 1006
L H +I++ G +K++ +V E++ G+L D + + + A
Sbjct 754 KLRHRNIVRLLGFLY--NDKNMMIVYEFMLNGNLGDAIHGKNAAGRLLVDWVSRYNIALG 811
Query 1007 ICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+ G+AYLH IHRD+ + N+LLD + +I DFGLA+ + E +
Sbjct 812 VAHGLAYLHHDCHPPVIHRDIKSNNILLDANLDARIADFGLARMMARKKETVSM---VAG 868
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM-TVL 1122
+ APE K D++S+GV L ELLT + + ++++ + ++ +
Sbjct 869 SYGYIAPEYGYTLKVDEKIDIYSYGVVLLELLTGRRPLEPEFGESVDIVEWVRRKIRDNI 928
Query 1123 RLTELLERGE---RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
L E L+ R + + V + C RP+ ++I +L + +
Sbjct 929 SLEEALDPNVGNCRYVQEEMLL--VLQIALLCTTKLPKDRPSMRDVISMLGEAKPRRKSN 986
Query 1180 A 1180
+
Sbjct 987 S 987
Score = 184 bits (466), Expect = 6e-46, Method: Composition-based stats.
Identities = 53/311 (17%), Positives = 109/311 (35%), Gaps = 68/311 (22%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
I + + +G G VY+ + +K L S
Sbjct 699 IKESNMIGMGATGIVYKA------------------------EMSRSSTVLAVKKLWRSA 734
Query 649 HDIAL----AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER- 703
DI F +L+ ++ H ++ + G ++V E++ +G L + +
Sbjct 735 ADIEDGTTGDFVGEVNLLGKLRHRNIVRLLGFLYNDKNMMIVYEFMLNGNLGDAIHGKNA 794
Query 704 -GHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKL 757
G + + W + +A +A L+YL + ++H ++ NILL + ++
Sbjct 795 AGRLLVDWVSRYNIALGVAHGLAYLHHDCHPPVIHRDIKSNNILLD-------ANLDARI 847
Query 758 SDPGVGLGALSREERV----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
+D G+ ++E V ++APE G + +D + +G LLE+ G
Sbjct 848 ADFGLARMMARKKETVSMVAGSYGYIAPEY--GYTLKVDEKIDIYSYGVVLLELL-TGRR 904
Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQ-------------------LATLTSQCLTYEPT 854
PL+ + + ++ + + + + C T P
Sbjct 905 PLEPEFGESVDIVEWVRRKIRDNISLEEALDPNVGNCRYVQEEMLLVLQIALLCTTKLPK 964
Query 855 QRPSFRTILRD 865
RPS R ++
Sbjct 965 DRPSMRDVISM 975
>sp|P17157|PHO85_YEAST Cyclin-dependent protein kinase PHO85 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=PHO85 PE=1 SV=2
Length=305
Score = 208 bits (529), Expect = 9e-59, Method: Composition-based stats.
Identities = 62/292 (21%), Positives = 114/292 (39%), Gaps = 36/292 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG G + V Y N TG VA+K +K D S +EI +++ L HE+I++
Sbjct 12 KLGNGTYATV----YKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVR 67
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFAQQICEGMAYL 1014
E L LV E++ L+ Y+ ++G L + F Q+ +G+A+
Sbjct 68 LYDVI--HTENKLTLVFEFMDN-DLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFC 124
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H +HRDL +N+L++ +K+GDFGLA+A +++ AP+ L
Sbjct 125 HENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIP---VNTFSSEVVTLWYRAPDVLM 181
Query 1075 EYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTK-----FLELIGIA------------- 1115
+ + + D+WS G L E++T + +++G
Sbjct 182 GSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPK 241
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
R L + + + + + + R + + +
Sbjct 242 YNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALH 293
Score = 170 bits (430), Expect = 1e-45, Method: Composition-based stats.
Identities = 47/268 (18%), Positives = 95/268 (35%), Gaps = 43/268 (16%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ QL LG GT VY+G + G + V LK +
Sbjct 5 SQFKQLEKLGNGTYATVYKGLNKTTG------------------------VYVALKEVKL 40
Query 647 SHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE--- 702
+ SLM ++ H ++ ++ V + +V E++++ L ++
Sbjct 41 DSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDN-DLKKYMDSRTVG 99
Query 703 --RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ + QL L++ ++H ++ +N+L+ + G +KL D
Sbjct 100 NTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRG-------QLKLGDF 152
Query 761 GVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
G+ + V + + AP+ L G+ + ST++D W G L E+
Sbjct 153 GLARAFGIPVNTFSSEVVTLWYRAPDVLM-GSRTYSTSIDIWSCGCILAEMITGKPLFPG 211
Query 817 SRSPSEKEHFYQRQHRLPEPSCPQLATL 844
+ + + + E P + L
Sbjct 212 TNDEEQLKLIFDIMGTPNESLWPSVTKL 239
>sp|Q9C5H5|M3K5G_ARATH Mitogen-activated protein kinase kinase
kinase 5 OS=Arabidopsis thaliana OX=3702 GN=MAPKKK5 PE=1 SV=1
Length=716
Score = 219 bits (559), Expect = 1e-58, Method: Composition-based stats.
Identities = 86/367 (23%), Positives = 143/367 (39%), Gaps = 49/367 (13%)
Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVF 892
L + C P P T + + +P +P +
Sbjct 291 LHPRLSTDVTNGRRDCCNVHPLPLPPGAT---------CSSSSAASVPSPQAPLKLDSFP 341
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD----CGPQHRSGWKQEI 948
KK + +G G FG V Y +N TG + A+K ++ + +QEI
Sbjct 342 MNSQWKKGKLIGRGTFGSV----YVASNSETGALCAMKEVELFPDDPKSAECIKQLEQEI 397
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQ 1006
+L L H +I++Y G + E + +EYV GS+ Y+ H ++ + + F +
Sbjct 398 KLLSNLQHPNIVQYFGS--ETVEDRFFIYLEYVHPGSINKYIRDHCGTMTESVVRNFTRH 455
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I G+AYLH + +HRD+ N+L+D +VK+ DFG+AK + R +
Sbjct 456 ILSGLAYLHNKKTVHRDIKGANLLVDASGVVKLADFGMAKHL----TGQRADLSLKGSPY 511
Query 1067 WYAPECLK-------EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119
W APE ++ +A D+WS G T+ E+ T PP E M
Sbjct 512 WMAPELMQAVMQKDSNPDLAFAVDIWSLGCTIIEMFTGK-----PPWSEFEGAAAMFKVM 566
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179
+ P P+ E ++ C++ + RPT L+ + + Q
Sbjct 567 -----------RDSPPIPESMSPEGKDFLRLCFQRNPAERPTASMLLEH-RFLKNSLQPT 614
Query 1180 APSVFSV 1186
+PS V
Sbjct 615 SPSNSDV 621
Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats.
Identities = 68/377 (18%), Positives = 123/377 (33%), Gaps = 38/377 (10%)
Query 539 RAGDDCFSLRR-CCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK-EITQLSHLG 596
R D + RR CC P + A+ + L + + +G
Sbjct 294 RLSTDVTNGRRDCCNVHPLPLPPGATCSSSSAASVPSPQAPLKLDSFPMNSQWKKGKLIG 353
Query 597 QGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFY 656
+GT +VY G+ + D DP +
Sbjct 354 RGTFGSVYVASNSETGALCAMKEVELFPD-------------------DPKSAECIKQLE 394
Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
+ L+S + H ++ G + EYV G ++ ++R G + + +
Sbjct 395 QEIKLLSNLQHPNIVQYFGSETVEDRFFIYLEYVHPGSINKYIRDHCGTMTESVVRNFTR 454
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---GALSREERV 773
+ S L+YL NK VH ++ G N+L+ G+ +KL+D G+ G +
Sbjct 455 HILSGLAYLHNKKTVHRDIKGANLLVDASGV-------VKLADFGMAKHLTGQRADLSLK 507
Query 774 ERIPWLAPECLPGGANSLST-----AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
W+APE + S A+D W G T++E+ F G+ P +
Sbjct 508 GSPYWMAPELMQAVMQKDSNPDLAFAVDIWSLGCTIIEM-FTGKPPWSEFEGAAAMFKVM 566
Query 829 RQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887
R +PE P+ C P +RP+ +L + +
Sbjct 567 RDSPPIPESMSPEGKDFLRLCFQRNPAERPTASMLLEHRFLKNSLQPTSPSNSDVSQLFN 626
Query 888 DPTVFHKRYLKKIRDLG 904
+ ++ +
Sbjct 627 GMNITEPSSRREKPNFK 643
>sp|G4NDR3|MCK1_PYRO7 Mitogen-activated protein kinase kinae kinase
MCK1 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617
/ FGSC 8958) OX=242507 GN=MCK1 PE=1 SV=1
Length=1528
Score = 226 bits (575), Expect = 1e-58, Method: Composition-based stats.
Identities = 78/338 (23%), Positives = 131/338 (39%), Gaps = 38/338 (11%)
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905
S L + T+ + + R S P K + +G+
Sbjct 1187 SALLRRKSTKMFNANIVQIRPNRDSMLVPDIPQDSISSSSRGAPKHPTTFRWFKGQLIGK 1246
Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKAL---------KADCGPQHRSGWKQEIDILRTLYH 956
G +G+V L N TGE +AVK + + + QEI+ ++ L H
Sbjct 1247 GTYGRVYLGM----NATTGEFLAVKEVEVNPRAAAGDKKRMKELVAALDQEIETMQHLDH 1302
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLH 1015
+I++Y GC ++ E S+ + +EY+ GS+ L ++ + + +Q G+AYLH
Sbjct 1303 VNIVQYLGC--ERKETSISIFLEYISGGSIGSCLRKNGKFEESVVQSLTRQTLSGLAYLH 1360
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK- 1074
+ +HRDL A N+LLD D KI DFG++K + VFW APE ++
Sbjct 1361 REGILHRDLKADNILLDVDGTAKISDFGISKK-TDNIYGNDKSNSMQGSVFWMAPEVIRS 1419
Query 1075 -EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ D+WS G + E+ + + + GE
Sbjct 1420 QGEGYSAKVDIWSLGCVVLEMFAGRRP---------------WAKEEAVGAIYKIANGEI 1464
Query 1134 LPRPDK----CPCEVYHLMKNCWETEASFRPTFENLIP 1167
P P+ M +C+ ++ RPT L+
Sbjct 1465 PPIPEDVQDTISPIAVAFMMDCFTVDSHDRPTANKLLS 1502
Score = 196 bits (498), Expect = 2e-49, Method: Composition-based stats.
Identities = 57/292 (20%), Positives = 96/292 (33%), Gaps = 35/292 (12%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ +G+GT VY G G + + + R +EL L
Sbjct 1240 KGQLIGKGTYGRVYLGMNATTGEFLAVKEVEVNPRAAAGDKKRMKELVAAL--------- 1290
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
+ M + H ++ G + + EY+ G + LR+ G +
Sbjct 1291 -----DQEIETMQHLDHVNIVQYLGCERKETSISIFLEYISGGSIGSCLRKN-GKFEESV 1344
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------ 764
+ +Q S L+YL + ++H ++ NILL G A K+SD G+
Sbjct 1345 VQSLTRQTLSGLAYLHREGILHRDLKADNILLDVDGTA-------KISDFGISKKTDNIY 1397
Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
G + W+APE + S +D W G +LE+ F G P
Sbjct 1398 GNDKSNSMQGSVFWMAPEVIRSQGEGYSAKVDIWSLGCVVLEM-FAGRRPWAKEEAVGAI 1456
Query 825 HFYQRQHRLP------EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
+ P + P C T + RP+ +L +
Sbjct 1457 YKIANGEIPPIPEDVQDTISPIAVAFMMDCFTVDSHDRPTANKLLSQHPFCE 1508
>sp|P39951|CDK1_RAT Cyclin-dependent kinase 1 OS=Rattus norvegicus
OX=10116 GN=Cdk1 PE=1 SV=1
Length=297
Score = 207 bits (527), Expect = 1e-58, Method: Composition-based stats.
Identities = 66/307 (21%), Positives = 124/307 (40%), Gaps = 38/307 (12%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+
Sbjct 1 MEDYIKIEKIGEGTYGVV----YKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQIC 1008
L H +I+ + + L L+ E++ + L+ YL P + + + + QI
Sbjct 57 ELRHPNIVSLQDVLMQ--DSRLYLIFEFLSM-DLKKYLDSIPPGQFMDSSLVKSYLYQIL 113
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+G+ + H++ +HRDL +N+L+D+ +K+ DFGLA+A RV +++
Sbjct 114 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP---IRVYTHEVVTLWYR 170
Query 1069 APECLKEY-KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
+PE L ++ D+WS G EL T +
Sbjct 171 SPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPE 230
Query 1128 LE--RGERLPRPDKCPCEVY-----------HLMKNCWETEASFR---------PTFENL 1165
+E + + P P + L+ + + R P F++L
Sbjct 231 VESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDL 290
Query 1166 IPILKTV 1172
+K +
Sbjct 291 DNQIKKM 297
Score = 164 bits (415), Expect = 1e-43, Method: Composition-based stats.
Identities = 42/267 (16%), Positives = 93/267 (35%), Gaps = 41/267 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ ++ +G+GT VY+GR R G V +K +
Sbjct 1 MEDYIKIEKIGEGTYGVVYKGRHRTTGQ------------------------IVAMKKIR 36
Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702
+ + SL+ ++ H ++ + V ++ ++ E++ L +L
Sbjct 37 LESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95
Query 703 RGHV-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
G + Q+ + + ++ ++H ++ +N+L+ G IKL+D G
Sbjct 96 PGQFMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKG-------TIKLADFG 148
Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ V + + +PE L G+ ST +D W G E+
Sbjct 149 LARAFGIPIRVYTHEVVTLWYRSPEVLL-GSARYSTPVDIWSIGTIFAELATKKPLFHGD 207
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ P++ +L
Sbjct 208 SEIDQLFRIFRALGTPNNEVWPEVESL 234
>sp|Q9FN93|Y5596_ARATH Probable LRR receptor-like serine/threonine-protein
kinase At5g59680 OS=Arabidopsis thaliana OX=3702
GN=At5g59680 PE=1 SV=1
Length=887
Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats.
Identities = 63/254 (25%), Positives = 114/254 (45%), Gaps = 12/254 (5%)
Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984
E VAVK L + Q +K E+D+L ++H +++ G C++ L L+ E+VP G
Sbjct 603 EQVAVK-LLSQSSTQGYKEFKAEVDLLLRVHHTNLVSLVGYCDEGDH--LALIYEFVPNG 659
Query 985 SLRDYLPRHS----IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLV 1037
LR +L + L A + G+ YLH +HRD+ N+LLD
Sbjct 660 DLRQHLSGKGGKPIVNWGTRLRIAAEAALGLEYLHIGCTPPMVHRDVKTTNILLDEHYKA 719
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097
K+ DFGL+++ P G E + +P + PE + SDV+SFG+ L E++T+
Sbjct 720 KLADFGLSRSFPVGGESHVSTVIAGTP-GYLDPEYYHTSRLSEKSDVYSFGIVLLEMITN 778
Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157
+ + + ++ + ++++ + L +C + ++
Sbjct 779 -QAVIDRNRRKSHITQWVGSELNGGDIAKIMDLKLNGDYDSRSAWRALELAMSCADPTSA 837
Query 1158 FRPTFENLIPILKT 1171
RPT +++ LK
Sbjct 838 RRPTMSHVVIELKE 851
Score = 191 bits (484), Expect = 2e-48, Method: Composition-based stats.
Identities = 48/193 (25%), Positives = 77/193 (40%), Gaps = 20/193 (10%)
Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697
+V +K+L S F L+ +V HT+L + G C G ++ E+V +G L
Sbjct 604 QVAVKLLSQSSTQGYKEFKAEVDLLLRVHHTNLVSLVGYCDEGDHLALIYEFVPNGDLRQ 663
Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTS 752
L + G + W ++ +A + A L YL +VH +V NILL
Sbjct 664 HLSGKGGKPIVNWGTRLRIAAEAALGLEYLHIGCTPPMVHRDVKTTNILLDE-------H 716
Query 753 PFIKLSDPGVGLG------ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
KL+D G+ + +L PE + LS D + FG LLE
Sbjct 717 YKAKLADFGLSRSFPVGGESHVSTVIAGTPGYLDPEYYHT--SRLSEKSDVYSFGIVLLE 774
Query 807 ICFDGEAPLQSRS 819
+ + ++R
Sbjct 775 MITNQAVIDRNRR 787
>sp|Q8BZN4|NUAK2_MOUSE NUAK family SNF1-like kinase 2 OS=Mus musculus
OX=10090 GN=Nuak2 PE=1 SV=2
Length=639
Score = 218 bits (554), Expect = 1e-58, Method: Composition-based stats.
Identities = 67/297 (23%), Positives = 113/297 (38%), Gaps = 36/297 (12%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938
+ + + LG+G +GKV + +G +VA+K+++ D
Sbjct 39 MKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKAR-----ESSGRLVAIKSIRKDKIK 93
Query 939 QHRS--GWKQEIDILRTLYHEHIIKYKGCCEDQ------GEKSLQLVMEYVPLGSLRDYL 990
+ ++EI+I+ +L H HII + + +VMEY G L DY+
Sbjct 94 DEQDLLHIRREIEIMSSLNHPHIIAIHEVGRSRLVTVFENSSKIVIVMEYASRGDLYDYI 153
Query 991 -PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049
R + F +QI + Y H +HRDL N+LLD + +KI DFGL+
Sbjct 154 SERPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYH 213
Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
+G + + + +PE + + D WS GV LY L+ K
Sbjct 214 KG----KFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKT 269
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L + + G P P + L++ + R T E++
Sbjct 270 ---------------LVKQISNGAYREPPK--PSDACGLIRWLLMVNPTRRATLEDV 309
Score = 170 bits (430), Expect = 1e-42, Method: Composition-based stats.
Identities = 52/292 (18%), Positives = 86/292 (29%), Gaps = 49/292 (17%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
L LG+GT V + R V +K +
Sbjct 58 EFLETLGKGTYGKVKKAR-------------------------ESSGRLVAIKSIRKDKI 92
Query 650 DIALAFY---ETASLMSQVSHTHLA--------FVHGVCVRGPENIMVTEYVEHGPLDVW 698
+MS ++H H+ + V + ++V EY G L +
Sbjct 93 KDEQDLLHIRREIEIMSSLNHPHIIAIHEVGRSRLVTVFENSSKIVIVMEYASRGDLYDY 152
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+ ER + +Q+ SAL Y +VH ++ NILL + IK++
Sbjct 153 I-SERPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLD-------ANGNIKIA 204
Query 759 DPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
D G+ + + +PE + G + +D W G L I G P
Sbjct 205 DFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPY-VGPEVDSWSLGVLLY-ILVHGTMPF 262
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ P L L PT+R + +
Sbjct 263 DGQDHKTLVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASHWW 314
>sp|Q8WNU8|NEK11_MACFA Serine/threonine-protein kinase Nek11 OS=Macaca
fascicularis OX=9541 GN=NEK11 PE=2 SV=1
Length=637
Score = 218 bits (554), Expect = 1e-58, Method: Composition-based stats.
Identities = 64/306 (21%), Positives = 117/306 (38%), Gaps = 28/306 (9%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
+ A + ++ P R + LG G FG V L G V
Sbjct 1 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKV- 59
Query 929 VKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987
+K + + P E +L L H I+K+ +Q + ++ EY L
Sbjct 60 LKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQD--NFCIITEYCEGRDLD 117
Query 988 DYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042
+ + Q++ + Q+ G+ Y+H + +HRDL ++N+ L N+ +KIGDF
Sbjct 118 YKIQEYKEAGKIFPDNQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNNL-LKIGDF 176
Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102
G+++ + + + +PE LK + SD+WS LYE+
Sbjct 177 GVSRLLMGSCDLATTLT---GTPHYMSPEALKHQGYDTKSDIWSLACILYEMC------- 226
Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162
+ A L + + G+ P++ P E+ +M++ S RP+
Sbjct 227 --------CMNHAFAGSNFLSIVLKIVEGDTPSLPERYPKELNTIMESMLNKNPSLRPSA 278
Query 1163 ENLIPI 1168
++ I
Sbjct 279 IEILKI 284
Score = 176 bits (447), Expect = 8e-45, Method: Composition-based stats.
Identities = 70/384 (18%), Positives = 114/384 (30%), Gaps = 54/384 (14%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LG G+ VY RG+EL+V LK + +
Sbjct 34 KLGSGSFGTVYL--------------------VSDKKAKRGEELKV-LKEISVGELNPNE 72
Query 654 AFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER---GHVPM 708
A L+S++ H + H V ++TEY E LD ++ + P
Sbjct 73 TVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDYKIQEYKEAGKIFPD 132
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
+ QL + Y+ + ++H ++ +NI L L K+ D GV +
Sbjct 133 NQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNNLL--------KIGDFGVSRLLMG 184
Query 769 R----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+++PE L T D W L E+C A S S
Sbjct 185 SCDLATTLTGTPHYMSPEALKH--QGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVL 242
Query 825 HFYQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRP------SFRTILRDLTRLQPHNLADV 877
+ LPE +L T+ L P+ RP I L L +
Sbjct 243 KIVEGDTPSLPERYPKELNTIMESMLNKNPSLRPSAIEILKIPYIDEQLQHLMCRHSEMT 302
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA---VKALKA 934
L + K+I +V A + LK
Sbjct 303 LEDKNLDCQKEAARLINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADERARKLKK 362
Query 935 DCGPQHRSGWKQEIDILRTLYHEH 958
++ K+ ++ L +
Sbjct 363 IVEEKYEENSKR----MQELRSRN 382
>sp|Q8IBS5|CDPK4_PLAF7 Calcium-dependent protein kinase 4 OS=Plasmodium
falciparum (isolate 3D7) OX=36329 GN=CDPK4 PE=1 SV=3
Length=528
Score = 214 bits (546), Expect = 1e-58, Method: Composition-based stats.
Identities = 68/272 (25%), Positives = 112/272 (41%), Gaps = 30/272 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960
LG+G FG+V L + TG A+K + + +E+++L+ L H +I+
Sbjct 76 LGKGSFGEVILS----RDKHTGHEYAIKVISKKHVKRKTDKESLLREVELLKMLDHINIM 131
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
K ED LV + G L D + R +QI G+ Y+H +
Sbjct 132 KLYEFFEDNN--YYYLVSDVYTGGELFDEIISRKRFYEIDAARIIKQILSGITYMHKNNV 189
Query 1020 IHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRDL N+LL D ++KI DFGL+ EY + +D ++ AP+ L
Sbjct 190 VHRDLKPENILLETKNKEDMIIKIIDFGLSTHF----EYSKKMKDKIGTAYYIAPDVL-H 244
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ D+WS GV LY LL+ C + +L+ E + LP
Sbjct 245 GTYDEKCDIWSCGVILYILLSGCPPFNG------------SNEYDILKKVEAGKYTFDLP 292
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ K + L+K ++ R + + +
Sbjct 293 QFKKISDKAKDLIKKMLMYTSAVRISARDALE 324
Score = 156 bits (394), Expect = 1e-38, Method: Composition-based stats.
Identities = 60/377 (16%), Positives = 122/377 (32%), Gaps = 52/377 (14%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ + LG+G+ V + RD+ +KV+
Sbjct 67 NEQYKGIKILGKGSFGEV------------------------ILSRDKHTGHEYAIKVIS 102
Query 646 PSHHDIA---LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
H + L+ + H ++ ++ +V++ G L +
Sbjct 103 KKHVKRKTDKESLLREVELLKMLDHINIMKLYEFFEDNNYYYLVSDVYTGGELFDEIISR 162
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ + + +Q+ S ++Y+ N+VH ++ NILL IK+ D G+
Sbjct 163 KRFYEID-AARIIKQILSGITYMHKNNVVHRDLKPENILL---ETKNKEDMIIKIIDFGL 218
Query 763 GLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
++ ++I ++AP+ L G + D W G L I G P +
Sbjct 219 STHFEYSKKMKDKIGTAYYIAPDVLHG---TYDEKCDIWSCGVILY-ILLSGCPPFNGSN 274
Query 820 PSEKEHFYQRQHR---LPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874
+ + LP+ + L + L Y R S R L +
Sbjct 275 EYDILKKVEAGKYTFDLPQFKKISDKAKDLIKKMLMYTSAVRISARDALEHEWIKMMTSK 334
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV-KALK 933
++ P S + + +K+ + + T D T E+ + K +
Sbjct 335 DNLNIDIPSLELSIANIRQFQSTQKLAQAAL-----LYMGSKLTTIDETKELTKIFKKMD 389
Query 934 ADCGPQHRSGWKQEIDI 950
+ Q + E+ I
Sbjct 390 KNGDGQLD---RNELII 403
>sp|Q54HC6|ARKA_DICDI Ankyrin repeat-containing protein kinase
A OS=Dictyostelium discoideum OX=44689 GN=arkA PE=1 SV=1
Length=1460
Score = 225 bits (574), Expect = 1e-58, Method: Composition-based stats.
Identities = 70/284 (25%), Positives = 122/284 (43%), Gaps = 15/284 (5%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+G G GKV Y G +VA+K LK+ R + +E +L +L
Sbjct 1114 YTEKIGSGASGKVFKGIYR------GRVVAIKVLKSADDEMTREDFLKEFGVLASLESHT 1167
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017
I+ G E + LVMEY GS+ + ++ + F QQ+ G+ LH
Sbjct 1168 IVGLYGVVL---EPKICLVMEYCSNGSIYHSIRKNPPSWERFFSFVQQMLAGINALHQST 1224
Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRD+ N L++++ VK+ DFGL++ E ++ + G S + APE +
Sbjct 1225 PQVLHRDIKTLNFLVNHNNKVKVADFGLSRFNTESNQETLNKTRGTSV--YCAPEVFEGK 1282
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
++ SD++S G+ ++E++ +C + E + L L +R R
Sbjct 1283 EYNERSDMYSMGIVMWEIV-YCVVYGCYMIPYQEYNKMFNAFQVAL-LVNSSKRVLRPTI 1340
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180
P P + L+ W+ + S RPT + L ++Y+
Sbjct 1341 PIGVPQVLKDLIYCLWDHDVSSRPTATEAMTALAVCEKEYKQNK 1384
Score = 156 bits (395), Expect = 4e-37, Method: Composition-based stats.
Identities = 59/414 (14%), Positives = 124/414 (30%), Gaps = 80/414 (19%)
Query 485 LTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLL--RAGD 542
L +A + L R I + LE + S + LQ + R +
Sbjct 998 LALAVDYDVCPEISDLLRRLDTITTSLEMYELEKFQASL-----VVEELQKENVVARLDE 1052
Query 543 DCFSLRRCCLPQPGET-----SNLIIMRG-ARASPRTLNLSQLSFHRVDQ-------KEI 589
C + SN +++ AR + L ++ + E+
Sbjct 1053 KLLDKIGCTDKEERRKFLSLKSNRLLIHHPARTQGAKIILKEMETMDIKNGKLIISETEL 1112
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
+G G V++G R V +KVL +
Sbjct 1113 EYTEKIGSGASGKVFKGIYRGR--------------------------VVAIKVLKSADD 1146
Query 650 DIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
++ F + +++ + + ++GV + P+ +V EY +G + +R+
Sbjct 1147 EMTREDFLKEFGVLASLESHTIVGLYGVVLE-PKICLVMEYCSNGSIYHSIRKN--PPSW 1203
Query 709 AWKMVVAQQLASALSYLENK--NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
QQ+ + ++ L ++H ++ N L+ + +K++D G+
Sbjct 1204 ERFFSFVQQMLAGINALHQSTPQVLHRDIKTLNFLVNH-------NNKVKVADFGLSRFN 1256
Query 767 LSR-----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ + APE G + D + G + EI +
Sbjct 1257 TESNQETLNKTRGTSVYCAPEVFEG--KEYNERSDMYSMGIVMWEIVYCVVYGCYMIPYQ 1314
Query 822 EKEHFYQR--------------QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861
E + + +P L L ++ + RP+
Sbjct 1315 EYNKMFNAFQVALLVNSSKRVLRPTIPIGVPQVLKDLIYCLWDHDVSSRPTATE 1368
>sp|Q7YRC6|AURKB_BOVIN Aurora kinase B OS=Bos taurus OX=9913 GN=AURKB
PE=2 SV=1
Length=344
Score = 209 bits (531), Expect = 1e-58, Method: Composition-based stats.
Identities = 73/330 (22%), Positives = 123/330 (37%), Gaps = 30/330 (9%)
Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898
P L TL + L EP + + R + V+ + +P F +
Sbjct 19 PGLNTLPQRVLRKEPVTPSALVLMSRSNAQPTAAPGQKVVENSSGTPNIPKRSFTIDDFE 78
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYH 956
R LG+G FG V L + +VA+K L + ++EI+I L H
Sbjct 79 IGRPLGKGKFGNVYL----AREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLQH 134
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLH 1015
+I++ D+ + + L++EY P G L L + + + +++ + + Y H
Sbjct 135 PNILRLYNYFYDR--RRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELADALTYCH 192
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
A+ IHRD+ N+LL +KI DFG + P R+ + + PE ++
Sbjct 193 AKKVIHRDIKPENLLLGLRGELKIADFGWSVHAPSLR-----RKTMCGTLDYLPPEMIEG 247
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
D+W GV YELL +S A T R+ ++ L
Sbjct 248 RTHNEKVDLWCIGVLCYELLVGNPPFES-----------ASHNETYRRIVKVD-----LK 291
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P P + + S R +
Sbjct 292 FPPSVPLGAQDFIYKLLKHNPSERLPLAQV 321
Score = 177 bits (450), Expect = 8e-48, Method: Composition-based stats.
Identities = 65/351 (19%), Positives = 117/351 (33%), Gaps = 50/351 (14%)
Query 530 GAALQGCLLR---AGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ 586
L +LR L QP ++ S T N+ + SF
Sbjct 21 LNTLPQRVLRKEPVTPSALVLMSRSNAQPTAAPGQKVVE---NSSGTPNIPKRSFTI--- 74
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ LG+G NVY R++ V LKVL
Sbjct 75 DDFEIGRPLGKGKFGNVYLA------------------------REKKSHFIVALKVLFK 110
Query 647 SHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
S + + + + + H ++ ++ ++ EY G L L++ R
Sbjct 111 SQIEKEGVEHQLRREIEIQAHLQHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSR 170
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ ++LA AL+Y K ++H ++ N+LL G +K++D G
Sbjct 171 -TFDEQRTATIMEELADALTYCHAKKVIHRDIKPENLLL-------GLRGELKIADFGWS 222
Query 764 LGALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ A S R+ + +L PE + G + + +D W G E+ G P +S S +
Sbjct 223 VHAPSLRRKTMCGTLDYLPPEMIEG--RTHNEKVDLWCIGVLCYELLV-GNPPFESASHN 279
Query 822 EK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
E + + P + L + P++R +
Sbjct 280 ETYRRIVKVDLKFPPSVPLGAQDFIYKLLKHNPSERLPLAQVSAHPWVRTH 330
>sp|F4I3V3|LRL15_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE
PROTEIN KINASE-like 1.5 OS=Arabidopsis thaliana
OX=3702 GN=LRK10L-1.5 PE=3 SV=1
Length=636
Score = 217 bits (553), Expect = 1e-58, Method: Composition-based stats.
Identities = 76/359 (21%), Positives = 134/359 (37%), Gaps = 37/359 (10%)
Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914
+ +I + + P + R +G+G FG V L
Sbjct 282 RASFLSSINEEDPAALFLRHHRSAALLPPVFTFEELESATNKFDPKRKIGDGGFGSVYLG 341
Query 915 CYDPTNDGTGEMVAVKALK----------ADCGPQHRSGWKQEIDILRTLYHEHIIKYKG 964
G+++AVK L C + EI IL ++ H +++K G
Sbjct 342 QL-----SDGQLLAVKFLHHHHGATAAATEHCKAFSMKSFCNEILILSSINHPNLVKLHG 396
Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHA---QHY 1019
C D + L LV +YV G+L D+L + L A Q M YLH
Sbjct 397 YCSDP--RGLLLVHDYVTNGTLADHLHGRGPKMTWRVRLDIALQTALAMEYLHFDIVPPV 454
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD-------SPVFWYAPEC 1072
+HRD+ + N+ ++ D +K+GDFGL++ + D + P+
Sbjct 455 VHRDITSSNIFVEKDMKIKVGDFGLSRLLVFSETTVNSATSSDYVCTGPQGTPGYLDPDY 514
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
+ ++ SDV+S+GV L EL+T + Q + + L + ++ + L ++++
Sbjct 515 HRSFRLTEKSDVYSYGVVLMELITGMKAVDQRREKRDMALADLVVSKIQMGLLDQVIDPL 574
Query 1132 ERLPRPDKCP-------CEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183
L D V L C T+ RP + ++ L+ + + V
Sbjct 575 LALDGDDVAAVSDGFGVAAVAELAFRCVATDKDDRPDAKEIVQELRRIRSHTRVADDDV 633
Score = 182 bits (461), Expect = 1e-46, Method: Composition-based stats.
Identities = 72/418 (17%), Positives = 125/418 (30%), Gaps = 57/418 (14%)
Query 440 PPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIH-------WSTSHPYRLILTVAQRSQ 492
P R++ HG L E Q L + + PY + Q
Sbjct 160 PGRILHGCES-THGSLSEQGCQGDLLGFLQDFFTRFGFEVEWDESQDPYFIKCRDCQIKN 218
Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRS-----FPSVRELGAALQGCLLR--AGDDCF 545
G S + I L + +V L AL LL F
Sbjct 219 GVCGFNSTHPNQDFICFHKSRSELVTQRDNNKRVNHIAVLSLIFALTCLLLVFSVAVAIF 278
Query 546 SLRRCCLPQPGETSN--LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603
RR + + +R R++ + + +G G +V
Sbjct 279 RSRRASFLSSINEEDPAALFLRHHRSAALLPPVFTFEELESATNKFDPKRKIGDGGFGSV 338
Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663
Y G+L + K +F ++S
Sbjct 339 YLGQLSDGQLLAVKFLHHHHGATAAATEH--------CKAFS------MKSFCNEILILS 384
Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723
++H +L +HG C ++V +YV +G L L + ++ +A Q A A+
Sbjct 385 SINHPNLVKLHGYCSDPRGLLLVHDYVTNGTLADHLHGRGPKMTWRVRLDIALQTALAME 444
Query 724 YLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV------- 773
YL +VH ++ NI + + IK+ D G+ + E V
Sbjct 445 YLHFDIVPPVVHRDITSSNIFVEK-------DMKIKVGDFGLSRLLVFSETTVNSATSSD 497
Query 774 -------ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+L P+ + L+ D + +G L+E+ +A Q R +
Sbjct 498 YVCTGPQGTPGYLDPDY--HRSFRLTEKSDVYSYGVVLMELITGMKAVDQRREKRDMA 553
>sp|Q9LJM4|IKU2_ARATH Receptor-like protein kinase HAIKU2 OS=Arabidopsis
thaliana OX=3702 GN=IKU2 PE=1 SV=1
Length=991
Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats.
Identities = 72/336 (21%), Positives = 128/336 (38%), Gaps = 36/336 (11%)
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK-- 930
+ V+ + + +K +G G G V +GE +AVK
Sbjct 647 QKKNDWQVSSFRLLNFNEMEIIDEIKSENIIGRGGQGNVYKVSLR-----SGETLAVKHI 701
Query 931 ---------------ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
L + ++ E+ L + H +++K C E S
Sbjct 702 WCPESSHESFRSSTAMLSDGNNRSNNGEFEAEVATLSNIKHINVVKL--FCSITCEDSKL 759
Query 976 LVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARN 1028
LV EY+P GSL + L IG A +G+ YLH + IHRD+ + N
Sbjct 760 LVYEYMPNGSLWEQLHERRGEQEIGWRVRQALALGAAKGLEYLHHGLDRPVIHRDVKSSN 819
Query 1029 VLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
+LLD + +I DFGLAK + + + + + APE K SDV+SF
Sbjct 820 ILLDEEWRPRIADFGLAKIIQADSVQRDFSAPLVKGTLGYIAPEYAYTTKVNEKSDVYSF 879
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQG---QMTVLRLTELLERGERLPRPDKCPCEV 1144
GV L EL+T ++ + +++ + + +L++ + +V
Sbjct 880 GVVLMELVTGKKPLETDFGENNDIVMWVWSVSKETNREMMMKLIDTSIEDEYKEDAL-KV 938
Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180
+ C + RP ++++ +L+ + Y +
Sbjct 939 LTIALLCTDKSPQARPFMKSVVSMLEKIEPSYNKNS 974
Score = 191 bits (485), Expect = 2e-48, Method: Composition-based stats.
Identities = 58/364 (16%), Positives = 122/364 (34%), Gaps = 50/364 (14%)
Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRT 601
F + N + + + L + + EI + +G+G +
Sbjct 625 ALFFLFSYVIFKIRRDKLNKTVQKKNDWQVSSFRLLNFNEMEII-DEIKSENIIGRGGQG 683
Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETAS 660
NVY+ LR + + + +L D ++ F +
Sbjct 684 NVYKVSLRSGETLAVKHIWCPESSHESFRSSTA--------MLSDGNNRSNNGEFEAEVA 735
Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQL 718
+S + H ++ + ++V EY+ +G L L RG + W++ +A
Sbjct 736 TLSNIKHINVVKLFCSITCEDSKLLVYEYMPNGSLWEQLHERRGEQEIGWRVRQALALGA 795
Query 719 ASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER--- 772
A L YL ++ ++H +V NILL +++D G+ + +
Sbjct 796 AKGLEYLHHGLDRPVIHRDVKSSNILLDEEWRP-------RIADFGLAKIIQADSVQRDF 848
Query 773 -----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA----------PLQS 817
+ ++APE ++ D + FG L+E+ + +
Sbjct 849 SAPLVKGTLGYIAPEYA--YTTKVNEKSDVYSFGVVLMELVTGKKPLETDFGENNDIVMW 906
Query 818 RSPSEKEHFYQRQHRLPEPSCPQ--------LATLTSQCLTYEPTQRPSFRTILRDLTRL 869
KE + +L + S + T+ C P RP ++++ L ++
Sbjct 907 VWSVSKETNREMMMKLIDTSIEDEYKEDALKVLTIALLCTDKSPQARPFMKSVVSMLEKI 966
Query 870 QPHN 873
+P
Sbjct 967 EPSY 970
>sp|Q84SN3|CDKF3_ORYSJ Cyclin-dependent kinase F-3 OS=Oryza sativa
subsp. japonica OX=39947 GN=CDKF-3 PE=2 SV=1
Length=433
Score = 212 bits (539), Expect = 1e-58, Method: Composition-based stats.
Identities = 76/289 (26%), Positives = 116/289 (40%), Gaps = 31/289 (11%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
K IR++G+G G V + N T E+VAVK +K +E+ L+
Sbjct 1 MERYKVIREIGDGTCGNV----FRAYNTETNEIVAVKKMKRKFFQWEECISLREVKALQK 56
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGM 1011
L H +I+K K + E L + E + +L D + + ++ F QI +G+
Sbjct 57 LNHPNIVKLKEVTMENHE--LFFIFENMEC-NLYDVIRERQAAFSEEEIRNFMVQILQGL 113
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
AY+H Y HRDL N+L+ D VKI DFGLA+ V Y D S ++ APE
Sbjct 114 AYMHNNGYFHRDLKPENLLVT-DGTVKIADFGLAREVSSSPPY----TDYVSTRWYRAPE 168
Query 1072 CLKEYK-FYYASDVWSFGVTLYELLTHCDSSQ---------------SPPTKFLELIGIA 1115
L + + A D+W+ G L EL T P + G+
Sbjct 169 VLLQSSAYTPAIDMWAVGAILAELFTLSPLFPGGSETDQLYKICAVLGTPDHTVWPEGMN 228
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164
+ + ++ R P E L++ + RPT E
Sbjct 229 LPRSSSFNFFQIPPRNLWELIP-NATLEAIDLIQQLCSWDPRRRPTAEQ 276
Score = 152 bits (385), Expect = 2e-38, Method: Composition-based stats.
Identities = 38/258 (15%), Positives = 75/258 (29%), Gaps = 38/258 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ + +G GT NV+ + V +K +
Sbjct 1 MERYKVIREIGDGTCGNVFRAY------------------------NTETNEIVAVKKMK 36
Query 646 PSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ +++H ++ + V + E + E +E L +R +
Sbjct 37 RKFFQWEECISLREVKALQKLNHPNIVKLKEVTMENHELFFIFENMEC-NLYDVIRERQA 95
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
Q+ L+Y+ N H ++ N+L+ +K++D G+
Sbjct 96 AFSEEEIRNFMVQILQGLAYMHNNGYFHRDLKPENLLVT--------DGTVKIADFGLAR 147
Query 765 GALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
S + V + APE L + + A+D W GA L E+
Sbjct 148 EVSSSPPYTDYVSTRWYRAPEVLLQSSA-YTPAIDMWAVGAILAELFTLSPLFPGGSETD 206
Query 822 EKEHFYQRQHRLPEPSCP 839
+ P
Sbjct 207 QLYKICAVLGTPDHTVWP 224
>sp|Q6BNF3|STE20_DEBHA Serine/threonine-protein kinase STE20 OS=Debaryomyces
hansenii (strain ATCC 36239 / CBS 767 / BCRC
21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=STE20
PE=3 SV=2
Length=1079
Score = 224 bits (570), Expect = 1e-58, Method: Composition-based stats.
Identities = 60/267 (22%), Positives = 119/267 (45%), Gaps = 22/267 (8%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+G+G G V + +D + + VA+K + + P+ + EI +++ HE+I+
Sbjct 805 MKIGQGASGGVYIA-HDVNHRS--QTVAIKQMNLEQQPK-KELIINEILVMKGSKHENIV 860
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ +G+ L +VMEY+ GSL + + + Q+ ++ +G+ +LH++ I
Sbjct 861 NFIDSYLLRGD--LWVVMEYMEGGSLTEIVTHSVMTEGQIGAVCRETLKGLRFLHSKGVI 918
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ + N+LL+ D +K+ DFG + +E R +W APE + ++
Sbjct 919 HRDIKSDNILLNIDGNIKMTDFGFCAQI---NEINLKRTTMVGTPYWMAPEVVSRKEYGP 975
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
DVWS G+ + E++ + T L IA +L P+
Sbjct 976 KVDVWSLGIMIIEMI-EGEPPYLNETPLRALYLIATNGTP------------KLKEPEAL 1022
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIP 1167
++ + C + + + R + L+
Sbjct 1023 SYDIRKFLSWCLQVDFNKRGNADQLLN 1049
Score = 179 bits (455), Expect = 2e-44, Method: Composition-based stats.
Identities = 56/303 (18%), Positives = 99/303 (33%), Gaps = 43/303 (14%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L Q+ + L +GQG VY + +
Sbjct 788 LQQICSEGDPNELYKDLMKIGQGASGGVY-----------------------IAHDVNHR 824
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
V +K ++ +M H ++ + + +V EY+E G L
Sbjct 825 SQTVAIKQMNLEQQPKKELIINEILVMKGSKHENIVNFIDSYLLRGDLWVVMEYMEGGSL 884
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+ + V ++ L +L +K ++H ++ NILL G I
Sbjct 885 TEIVTHS--VMTEGQIGAVCRETLKGLRFLHSKGVIHRDIKSDNILLNIDG-------NI 935
Query 756 KLSDPGVGLGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811
K++D G L R V W+APE + +D W G ++E+ +G
Sbjct 936 KMTDFGFCAQINEINLKRTTMVGTPYWMAPEVVS--RKEYGPKVDVWSLGIMIIEMI-EG 992
Query 812 EAPLQSRSPSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
E P + +P + PE + S CL + +R + +L D
Sbjct 993 EPPYLNETPLRALYLIATNGTPKLKEPEALSYDIRKFLSWCLQVDFNKRGNADQLLNDKF 1052
Query 868 RLQ 870
L+
Sbjct 1053 ILE 1055
>sp|O74456|PEF1_SCHPO Serine/threonine-protein kinase pef1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=pef1 PE=3 SV=2
Length=288
Score = 207 bits (526), Expect = 1e-58, Method: Composition-based stats.
Identities = 56/212 (26%), Positives = 105/212 (50%), Gaps = 15/212 (7%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+++ LGEG + V Y N TGE+VA+K ++ D S +EI +++ L
Sbjct 1 MNYQRLEKLGEGTYAHV----YKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKEL 56
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEG 1010
H +I+ Q E L LV EY+ L+ Y+ + ++ +Q+ F QQ+ +G
Sbjct 57 RHPNIMSLSDVL--QTENKLMLVFEYMEK-DLKKYMDTYGNQGALPPSQVKNFTQQLLKG 113
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
+++ H +HRDL +N+L+++ +K+ DFGLA+++ + +++ AP
Sbjct 114 ISFCHENRVLHRDLKPQNLLINSRGELKLADFGLARSIGIP---VNTFSNEVVTLWYRAP 170
Query 1071 ECLKEYK-FYYASDVWSFGVTLYELLTHCDSS 1101
+ L + + + D+WS G + E+ T
Sbjct 171 DVLLGSRVYSTSIDIWSVGCIMAEMATGRPLF 202
Score = 167 bits (422), Expect = 1e-44, Method: Composition-based stats.
Identities = 55/264 (21%), Positives = 103/264 (39%), Gaps = 40/264 (15%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+L LG+GT +VY+G+ RV G V LKV+
Sbjct 2 NYQRLEKLGEGTYAHVYKGQNRVTGE------------------------IVALKVIRID 37
Query 648 HHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL--RRERG 704
+ SLM ++ H ++ + V + ++V EY+E L ++ +G
Sbjct 38 ADEGTPSTAIREISLMKELRHPNIMSLSDVLQTENKLMLVFEYMEK-DLKKYMDTYGNQG 96
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+P + QQL +S+ ++H ++ +N+L+ G +KL+D G+
Sbjct 97 ALPPSQVKNFTQQLLKGISFCHENRVLHRDLKPQNLLINSRGE-------LKLADFGLAR 149
Query 765 GA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+ V + + AP+ L G+ ST++D W G + E+ S +
Sbjct 150 SIGIPVNTFSNEVVTLWYRAPDVLL-GSRVYSTSIDIWSVGCIMAEMATGRPLFAGSNNE 208
Query 821 SEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ E S P ++ L
Sbjct 209 DQLLKIFRLLGTPTEQSWPGISLL 232
>sp|Q7ZX15|AKT2A_XENLA RAC-beta serine/threonine-protein kinase
A OS=Xenopus laevis OX=8355 GN=akt2-a PE=2 SV=1
Length=486
Score = 213 bits (543), Expect = 1e-58, Method: Composition-based stats.
Identities = 68/309 (22%), Positives = 106/309 (34%), Gaps = 28/309 (9%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
Q P + + + + ++ LG+G FGKV L
Sbjct 114 NQVPEDEEEEAMEVKYGSPSDVSSAEQMDVAMSKGHPKVTMNDFDYLKLLGKGTFGKVIL 173
Query 914 YCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971
TG A+K L+ + + E +L+ H + K Q
Sbjct 174 V----REKATGRYYAMKILRKEVIIAKDEVAHTLTESRVLQNTKHPFLTALKYAF--QTS 227
Query 972 KSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030
L VMEY G L +L R + + +I + YLH+++ ++RD+ N++
Sbjct 228 DRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRNVVYRDIKLENLM 287
Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
LD D VKI DFGL K EG + APE L++ + A D W GV
Sbjct 288 LDKDGHVKITDFGLCK---EGITDGATMRTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVV 344
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
+YE++ Q +L R PR E L+
Sbjct 345 MYEMMCGRLPF--------------YNQDHERLFELILMEEIRFPR--TLSPEAKSLLAG 388
Query 1151 CWETEASFR 1159
+ + R
Sbjct 389 LLKKDPKQR 397
Score = 167 bits (423), Expect = 8e-43, Method: Composition-based stats.
Identities = 56/283 (20%), Positives = 96/283 (34%), Gaps = 43/283 (15%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+V + L LG+GT V + R++ +
Sbjct 150 PKVTMNDFDYLKLLGKGTFGKV------------------------ILVREKATGRYYAM 185
Query 642 KVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
K+L + ++ H L + V EY G L
Sbjct 186 KILRKEVIIAKDEVAHTLTESRVLQNTKHPFLTALKYAFQTSDRLCFVMEYANGGELFFH 245
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
L RER ++ SAL YL ++N+V+ ++ N++L + G +K++
Sbjct 246 LSRER-VFTEDRARFYGAEIVSALEYLHSRNVVYRDIKLENLMLDKDG-------HVKIT 297
Query 759 DPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
D G+ ++ +LAPE L N A+D WG G + E+ G P
Sbjct 298 DFGLCKEGITDGATMRTFCGTPEYLAPEVLED--NDYGRAVDWWGLGVVMYEMMC-GRLP 354
Query 815 LQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
++ + R P P+ +L + L +P QR
Sbjct 355 FYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQR 397
>sp|Q86SG6|NEK8_HUMAN Serine/threonine-protein kinase Nek8 OS=Homo
sapiens OX=9606 GN=NEK8 PE=1 SV=1
Length=692
Score = 218 bits (556), Expect = 1e-58, Method: Composition-based stats.
Identities = 66/269 (25%), Positives = 120/269 (45%), Gaps = 30/269 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V L ++V +K + + + R + E +L+ L H ++I+
Sbjct 10 VGRGAFGIVHLCLRKA----DQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIE 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018
Y + +K+L + MEY P G+L +++ + + +L F QI + ++H
Sbjct 66 YYENFLE--DKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHL 123
Query 1019 YIHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL +N+LLD +VKIGDFG++K + + Y V + +PE +
Sbjct 124 ILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTV----VGTPCYISPELCEGKP 179
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ SD+W+ G LYEL + + ++ L L + G P
Sbjct 180 YNQKSDIWALGCVLYELASLKRAFEAANLPALVL---------------KIMSGTFAPIS 224
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
D+ E+ L+ + E + RP +++
Sbjct 225 DRYSPELRQLVLSLLSLEPAQRPPLSHIM 253
Score = 166 bits (419), Expect = 5e-41, Method: Composition-based stats.
Identities = 44/292 (15%), Positives = 101/292 (35%), Gaps = 39/292 (13%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ ++ +G+G V+ + + + V++K +
Sbjct 1 MEKYERIRVVGRGAFGIVHLCLRKAD------------------------QKLVIIKQIP 36
Query 646 PSHH--DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ A ++ ++H ++ + + ++ EY G L ++++
Sbjct 37 VEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRC 96
Query 704 GH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ + Q+ AL ++ ++H ++ +NILL + +K+ D G+
Sbjct 97 NSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKH------RMVVKIGDFGI 150
Query 763 GLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
S+ V +++PE G + D W G L E+ A +
Sbjct 151 SKILSSKSKAYTVVGTPCYISPELCEG--KPYNQKSDIWALGCVLYELASLKRAFEAANL 208
Query 820 PSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P+ + + P+L L L+ EP QRP I+ ++
Sbjct 209 PALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIR 260
>sp|Q19469|SAD1_CAEEL Serine/threonine kinase SAD-1 OS=Caenorhabditis
elegans OX=6239 GN=sad-1 PE=1 SV=2
Length=914
Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats.
Identities = 76/310 (25%), Positives = 128/310 (41%), Gaps = 29/310 (9%)
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920
I L + + +++ N S + K + LG+G G V T+
Sbjct 11 EINSKLAAVNNELSSKIMSENIVSTRPVAQAQYCGPYKLEKTLGKGQTGLVKTG----TH 66
Query 921 DGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979
TG VA+K + + + ++EI I++ + H H++ E++ K L L++E
Sbjct 67 CITGRKVAIKIVNKEKLSESVLQKVEREIAIMKLIEHPHVLHLYDVYENK--KYLYLLLE 124
Query 980 YVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
+V G L DYL + + + F +QI + + HA + HRDL N+LLD +K
Sbjct 125 HVSGGELFDYLVRKGRLMSKEARKFFRQIISALDFCHAHNICHRDLKPENLLLDERNNIK 184
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTH 1097
+ DFG+A EG + E + PE ++ K+ +DVWS GV LY LL
Sbjct 185 VADFGMASLQVEG----SMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVG 240
Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157
+ L E ++RG P P +V L++ E +
Sbjct 241 ALPFDDD---------------NLRNLLEKVKRGV-FHIPHFVPADVQSLLRAMIEVDPG 284
Query 1158 FRPTFENLIP 1167
R + ++
Sbjct 285 KRYSLADVFK 294
Score = 165 bits (418), Expect = 2e-40, Method: Composition-based stats.
Identities = 53/322 (16%), Positives = 106/322 (33%), Gaps = 44/322 (14%)
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEI----TQLSHLGQGTRTNVYEGRLRVE 611
GE ++ + S + ++ + +S V Q + LG+G V G +
Sbjct 10 GEINSKLAAVNNELSSKIMSENIVSTRPVAQAQYCGPYKLEKTLGKGQTGLVKTGTHCIT 69
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSHTH 669
G +V +K+++ + ++M + H H
Sbjct 70 GR------------------------KVAIKIVNKEKLSESVLQKVEREIAIMKLIEHPH 105
Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729
+ ++ V ++ E+V G L +L +G + +Q+ SAL + N
Sbjct 106 VLHLYDVYENKKYLYLLLEHVSGGELFDYL-VRKGRLMSKEARKFFRQIISALDFCHAHN 164
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR---EERVERIPWLAPECLPG 786
+ H ++ N+LL IK++D G+ + E + PE + G
Sbjct 165 ICHRDLKPENLLLDERN-------NIKVADFGMASLQVEGSMLETSCGSPHYACPEVIRG 217
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLT 845
D W G L + G P + +R +P + +L
Sbjct 218 EKYD-GRKADVWSCGVILYALLV-GALPFDDDNLRNLLEKVKRGVFHIPHFVPADVQSLL 275
Query 846 SQCLTYEPTQRPSFRTILRDLT 867
+ +P +R S + +
Sbjct 276 RAMIEVDPGKRYSLADVFKHPW 297
>sp|Q02723|RKIN1_SECCE Carbon catabolite-derepressing protein
kinase OS=Secale cereale OX=4550 GN=RKIN1 PE=2 SV=1
Length=502
Score = 214 bits (544), Expect = 2e-58, Method: Composition-based stats.
Identities = 74/283 (26%), Positives = 108/283 (38%), Gaps = 33/283 (12%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQE 947
+ + LG G F KV + + T VA+K L P+ K+E
Sbjct 7 HSEALKNYYLGKILGVGTFAKVII----AEHKHTRHKVAIKVLNRRQMRAPEMEEKAKRE 62
Query 948 IDILRT---LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLF 1003
I ILR L H HII+ K + +VMEY G L DY L + + +
Sbjct 63 IKILRLFIDLIHPHIIRVYEVIV--TPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRT 120
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
QQI + Y H +HRDL N+LLD+ VK+ DFGL+ + +GH +
Sbjct 121 FQQIISAVEYCHRNKVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGH----FLKTSCG 176
Query 1064 PVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122
+ + APE + + DVWS GV LY LL +
Sbjct 177 SLNYAAPEVISGKLYAGPEIDVWSCGVILYALLCGAVPFDDD---------------NIP 221
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L + ++ G + P V L+ + R T +
Sbjct 222 NLFKKIKGGTYI-LPIYLSDLVRDLISRMLIVDPMKRITIGEI 263
Score = 175 bits (444), Expect = 2e-45, Method: Composition-based stats.
Identities = 54/335 (16%), Positives = 102/335 (30%), Gaps = 42/335 (13%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
H K LG GT V + + +V +
Sbjct 7 HSEALKNYYLGKILGVGTFAKV------------------------IIAEHKHTRHKVAI 42
Query 642 KVLDPSHH---DIALAFYETASLMS---QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
KVL+ ++ ++ + H H+ V+ V V + +V EY ++G L
Sbjct 43 KVLNRRQMRAPEMEEKAKREIKILRLFIDLIHPHIIRVYEVIVTPKDIFVVMEYCQNGDL 102
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
++ +R + QQ+ SA+ Y +VH ++ N+LL +
Sbjct 103 LDYILEKR-RLQEDEARRTFQQIISAVEYCHRNKVVHRDLKPENLLLDSK-------YNV 154
Query 756 KLSDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
KL+D G+ + + + APE + G + +D W G L +
Sbjct 155 KLADFGLSNVMHDGHFLKTSCGSLNYAAPEVISGKLYA-GPEIDVWSCGVILYALLCGAV 213
Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
P+ + + LP + L S+ L +P +R + I +
Sbjct 214 PFDDDNIPNLFKKIKGGTYILPIYLSDLVRDLISRMLIVDPMKRITIGEIRKHSWFQNRL 273
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907
+ + + H
Sbjct 274 PRYLAVPPPDMMQQAKMIDEDTLRDVVKLGYDKDH 308
>sp|P06493|CDK1_HUMAN Cyclin-dependent kinase 1 OS=Homo sapiens
OX=9606 GN=CDK1 PE=1 SV=3
Length=297
Score = 207 bits (526), Expect = 2e-58, Method: Composition-based stats.
Identities = 62/287 (22%), Positives = 117/287 (41%), Gaps = 29/287 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+
Sbjct 1 MEDYTKIEKIGEGTYGVV----YKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQIC 1008
L H +I+ + + L L+ E++ + L+ YL P + + + + QI
Sbjct 57 ELRHPNIVSLQDVLMQ--DSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLYQIL 113
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+G+ + H++ +HRDL +N+L+D+ +K+ DFGLA+A RV +++
Sbjct 114 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP---IRVYTHEVVTLWYR 170
Query 1069 APECLKEY-KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
+PE L ++ D+WS G EL T +
Sbjct 171 SPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPE 230
Query 1128 LE--RGERLPRPDKCPCEVY-----------HLMKNCWETEASFRPT 1161
+E + + P P + L+ + + R +
Sbjct 231 VESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS 277
Score = 165 bits (417), Expect = 5e-44, Method: Composition-based stats.
Identities = 41/267 (15%), Positives = 95/267 (36%), Gaps = 41/267 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ T++ +G+GT VY+GR + G V +K +
Sbjct 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQ------------------------VVAMKKIR 36
Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-- 701
+ + SL+ ++ H ++ + V ++ ++ E++ L +L
Sbjct 37 LESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
++ + Q+ + + ++ ++H ++ +N+L+ G IKL+D G
Sbjct 96 PGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKG-------TIKLADFG 148
Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ V + + +PE L G+ ST +D W G E+
Sbjct 149 LARAFGIPIRVYTHEVVTLWYRSPEVLL-GSARYSTPVDIWSIGTIFAELATKKPLFHGD 207
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ P++ +L
Sbjct 208 SEIDQLFRIFRALGTPNNEVWPEVESL 234
>sp|D3ZGQ5|NEK8_RAT Serine/threonine-protein kinase Nek8 OS=Rattus
norvegicus OX=10116 GN=Nek8 PE=1 SV=1
Length=698
Score = 218 bits (556), Expect = 2e-58, Method: Composition-based stats.
Identities = 66/269 (25%), Positives = 120/269 (45%), Gaps = 30/269 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V L ++V +K + + + R + E +L+ L H ++I+
Sbjct 10 VGRGAFGIVHLCLRKA----DQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIE 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018
Y + +K+L + MEY P G+L +++ + + +L F QI + ++H
Sbjct 66 YYENFLE--DKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHL 123
Query 1019 YIHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL +N+LLD +VKIGDFG++K + + Y V + +PE +
Sbjct 124 ILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTV----VGTPCYISPELCEGKP 179
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ SD+W+ G LYEL + + ++ L L + G P
Sbjct 180 YNQKSDIWALGCVLYELASLKRAFEAANLPALVL---------------KIMSGTFAPIS 224
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
D+ E+ L+ + E + RP +++
Sbjct 225 DRYSPELRQLVLSLLSLEPAQRPPLSHIM 253
Score = 166 bits (419), Expect = 5e-41, Method: Composition-based stats.
Identities = 44/292 (15%), Positives = 101/292 (35%), Gaps = 39/292 (13%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ ++ +G+G V+ + + + V++K +
Sbjct 1 MEKYERIRVVGRGAFGIVHLCLRKAD------------------------QKLVIIKQIP 36
Query 646 PSHH--DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ A ++ ++H ++ + + ++ EY G L ++++
Sbjct 37 VEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRC 96
Query 704 GH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ + Q+ AL ++ ++H ++ +NILL + +K+ D G+
Sbjct 97 NSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKH------RMVVKIGDFGI 150
Query 763 GLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
S+ V +++PE G + D W G L E+ A +
Sbjct 151 SKILSSKSKAYTVVGTPCYISPELCEG--KPYNQKSDIWALGCVLYELASLKRAFEAANL 208
Query 820 PSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P+ + + P+L L L+ EP QRP I+ ++
Sbjct 209 PALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIR 260
>sp|P35567|CDK1A_XENLA Cyclin-dependent kinase 1-A OS=Xenopus
laevis OX=8355 GN=cdk1-a PE=1 SV=1
Length=302
Score = 207 bits (526), Expect = 2e-58, Method: Composition-based stats.
Identities = 68/303 (22%), Positives = 125/303 (41%), Gaps = 33/303 (11%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+
Sbjct 1 MDEYTKIEKIGEGTYGVV----YKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQIC 1008
L H +I+ + L L+ E++ + L+ YL I + + QI
Sbjct 57 ELQHPNIVCLLDVLMQ--DSRLYLIFEFLSM-DLKKYLDSIPSGQYIDTMLVKSYLYQIL 113
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+G+ + H++ +HRDL +N+L+D+ ++K+ DFGLA+A RV +++
Sbjct 114 QGIVFCHSRRVLHRDLKPQNLLIDSKGVIKLADFGLARAFGIP---VRVYTHEVVTLWYR 170
Query 1069 APECLKEY-KFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQMTVL 1122
APE L ++ DVWS G E+ T H DS + +G ++
Sbjct 171 APEVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEV-WP 229
Query 1123 RLTELLERGERLPR---------PDKCPCEVYHLMKNCWETEASFRPTFEN--LIPILKT 1171
+ L + P+ + L+ + + R + L P
Sbjct 230 EVESLQDYKNSFPKWKGGSLSANVKNIDKDGLDLLAKMLIYDPAKRISARKALLHPYFDD 289
Query 1172 VHE 1174
+ +
Sbjct 290 LDK 292
Score = 169 bits (427), Expect = 3e-45, Method: Composition-based stats.
Identities = 45/267 (17%), Positives = 94/267 (35%), Gaps = 41/267 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
E T++ +G+GT VY+GR + G V +K
Sbjct 1 MDEYTKIEKIGEGTYGVVYKGRHKATGQ------------------------VVAMKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-- 701
L+ + SL+ ++ H ++ + V ++ ++ E++ L +L
Sbjct 37 LENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
++ Q+ + + ++ ++H ++ +N+L+ G+ IKL+D G
Sbjct 96 SGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDSKGV-------IKLADFG 148
Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ V + + APE L G+ ST +D W G EI
Sbjct 149 LARAFGIPVRVYTHEVVTLWYRAPEVLL-GSVRYSTPVDVWSIGTIFAEIATKKPLFHGD 207
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ P++ +L
Sbjct 208 SEIDQLFRIFRALGTPNNEVWPEVESL 234
>sp|Q61083|M3K2_MOUSE Mitogen-activated protein kinase kinase
kinase 2 OS=Mus musculus OX=10090 GN=Map3k2 PE=1 SV=2
Length=619
Score = 217 bits (552), Expect = 2e-58, Method: Composition-based stats.
Identities = 73/281 (26%), Positives = 126/281 (45%), Gaps = 24/281 (9%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL----KADCGPQHRSGWKQ 946
+ + LG+G FG+V L + TG +AVK + ++ + + +
Sbjct 350 PRAPTNWRLGKLLGQGAFGRVYLCY----DVDTGRELAVKQVQFNPESPETSKEVNALEC 405
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQ 1005
EI +L+ L HE I++Y GC D EK+L + ME P GS++D L + + + +
Sbjct 406 EIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKAYGALTENVTRKYTR 465
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
QI EG+ YLH+ +HRD+ N+L D+ +K+GDFG +K + +
Sbjct 466 QILEGVHYLHSNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTP 525
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+W +PE + + +D+WS T+ E+LT + PP E + +
Sbjct 526 YWMSPEVISGEGYGRKADIWSVACTVVEMLT-----EKPPWAEFEAMA---------AIF 571
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
++ + P +K + EA RP+ E L+
Sbjct 572 KIATQPTNPKLPPHVSDYTRDFLKRIF-VEAKLRPSAEELL 611
Score = 158 bits (400), Expect = 5e-39, Method: Composition-based stats.
Identities = 63/335 (19%), Positives = 104/335 (31%), Gaps = 52/335 (16%)
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQK---EITQLSHLGQGTRTNVYEGRLRVE 611
P + I RG+ TL ++ +S + LGQG VY
Sbjct 319 PEYDDSRIRRRGSDIDNPTLTVTDISPPSRSPRAPTNWRLGKLLGQGAFGRVY------- 371
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE---TASLMSQVSHT 668
L D G+EL V +P + + L+ + H
Sbjct 372 ---------------LCYDVDTGRELAVKQVQFNPESPETSKEVNALECEIQLLKNLLHE 416
Query 669 HLAFVHGVCVRGPE--NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726
+ +G E + E G + L+ G + +Q+ + YL
Sbjct 417 RIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKA-YGALTENVTRKYTRQILEGVHYLH 475
Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-------VGLGALSREERVERIPWL 779
+ +VH ++ G NIL ++ IKL D G + L + W+
Sbjct 476 SNMIVHRDIKGANIL-------RDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTPYWM 528
Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP 839
+PE + G D W T++E+ E P + + F P
Sbjct 529 SPEVISG--EGYGRKADIWSVACTVVEMLT--EKPPWAEFEAMAAIFKIATQPTNPKLPP 584
Query 840 QLATLTSQCLTY---EPTQRPSFRTILRDLTRLQP 871
++ T L E RPS +LR +
Sbjct 585 HVSDYTRDFLKRIFVEAKLRPSAEELLRHMFVHYH 619
>sp|O64477|Y2913_ARATH G-type lectin S-receptor-like serine/threonine-protein
kinase At2g19130 OS=Arabidopsis thaliana OX=3702
GN=At2g19130 PE=2 SV=1
Length=828
Score = 221 bits (562), Expect = 2e-58, Method: Composition-based stats.
Identities = 77/300 (26%), Positives = 127/300 (42%), Gaps = 23/300 (8%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946
LG G FG V ++D +AVK L + Q ++
Sbjct 483 FSYRELQNATKNFSDKLGGGGFGSVFKGALPDSSD-----IAVKRL--EGISQGEKQFRT 535
Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQL 1000
E+ + T+ H ++++ +G C + +K LV +Y+P GSL +L + +G
Sbjct 536 EVVTIGTIQHVNLVRLRGFCSEGSKK--LLVYDYMPNGSLDSHLFLNQVEEKIVLGWKLR 593
Query 1001 LLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
A G+AYLH + IH D+ N+LLD+ K+ DFGLAK V G ++ RV
Sbjct 594 FQIALGTARGLAYLHDECRDCIIHCDIKPENILLDSQFCPKVADFGLAKLV--GRDFSRV 651
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQ 1116
+ APE + +DV+S+G+ L+EL++ ++ QS K A
Sbjct 652 LTTMRGTRGYLAPEWISGVAITAKADVYSYGMMLFELVSGRRNTEQSENEKVRFFPSWAA 711
Query 1117 GQMTVL-RLTELLERGERLPRPD-KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
+T + L++ D + + C + E S RP ++ IL+ V E
Sbjct 712 TILTKDGDIRSLVDPRLEGDAVDIEEVTRACKVACWCIQDEESHRPAMSQVVQILEGVLE 771
Score = 196 bits (499), Expect = 2e-50, Method: Composition-based stats.
Identities = 51/271 (19%), Positives = 91/271 (34%), Gaps = 48/271 (18%)
Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634
LS S+ + LG G +V++G L
Sbjct 479 TLSAFSYRELQNATKNFSDKLGGGGFGSVFKGALPDSSD--------------------- 517
Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
+ +K L F + + H +L + G C G + ++V +Y+ +G
Sbjct 518 ----IAVKRL-EGISQGEKQFRTEVVTIGTIQHVNLVRLRGFCSEGSKKLLVYDYMPNGS 572
Query 695 LDVWLR----RERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGL 747
LD L E+ + + +A A L+YL + ++H ++ NILL
Sbjct 573 LDSHLFLNQVEEKIVLGWKLRFQIALGTARGLAYLHDECRDCIIHCDIKPENILLDSQFC 632
Query 748 AEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGA 802
K++D G+ RV +LAPE + G A ++ D + +G
Sbjct 633 P-------KVADFGLAKLVGRDFSRVLTTMRGTRGYLAPEWISGVA--ITAKADVYSYGM 683
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833
L E+ G + + F +
Sbjct 684 MLFELVS-GRRNTEQSENEKVRFFPSWAATI 713
>sp|Q6BRY2|PHO85_DEBHA Negative regulator of the PHO system OS=Debaryomyces
hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394
/ JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=PHO85 PE=3
SV=2
Length=330
Score = 208 bits (529), Expect = 2e-58, Method: Composition-based stats.
Identities = 69/297 (23%), Positives = 122/297 (41%), Gaps = 30/297 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+++ LGEG + V Y N G++VA+K + D S +EI
Sbjct 1 MTGSSSQFQQLEKLGEGTYATV----YKGRNRTNGQLVALKEINLDSEEGTPSTAIREIS 56
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQ 1005
+++ L HE+I+ E L LV E++ L+ Y+ H + L + F
Sbjct 57 LMKELDHENIVTLYDVI--HTENKLTLVFEFMDK-DLKKYMEAHGNQGALDLKIVKSFIF 113
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
Q+ +G+ + H +HRDL +N+L++N +K+GDFGLA+A + + +
Sbjct 114 QLLKGIMFCHDNRVLHRDLKPQNLLINNKGELKLGDFGLARAFGIP---FNTFSNEVVTL 170
Query 1066 FWYAPECLKEYKFYYAS-DVWSFGVTLYELLTHCD-----SSQSPPTKFLELIGIAQGQ- 1118
++ AP+ L + Y AS D+WS G E+ T S+ K L+G +
Sbjct 171 WYRAPDVLLGSRAYTASIDIWSAGCIFAEMCTGKPLFPGTSNDDQLIKIFRLMGTPNERT 230
Query 1119 --------MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + RL P+ + +L+ + + R T +
Sbjct 231 WPGVSSYANFKNNWQIFVPQDLRLLIPNLDSMGL-NLLSSLLQMRPDARITARQALQ 286
Score = 168 bits (425), Expect = 1e-44, Method: Composition-based stats.
Identities = 46/264 (17%), Positives = 99/264 (38%), Gaps = 40/264 (15%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ QL LG+GT VY+GR R G V LK ++
Sbjct 6 SQFQQLEKLGEGTYATVYKGRNRTNGQ------------------------LVALKEINL 41
Query 647 SHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL--RRER 703
+ SLM ++ H ++ ++ V + +V E+++ L ++ +
Sbjct 42 DSEEGTPSTAIREISLMKELDHENIVTLYDVIHTENKLTLVFEFMDK-DLKKYMEAHGNQ 100
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
G + + QL + + + ++H ++ +N+L+ G +KL D G+
Sbjct 101 GALDLKIVKSFIFQLLKGIMFCHDNRVLHRDLKPQNLLINNKGE-------LKLGDFGLA 153
Query 764 LG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ V + + AP+ L G+ + + ++D W G E+C + +
Sbjct 154 RAFGIPFNTFSNEVVTLWYRAPDVLL-GSRAYTASIDIWSAGCIFAEMCTGKPLFPGTSN 212
Query 820 PSEKEHFYQRQHRLPEPSCPQLAT 843
+ ++ E + P +++
Sbjct 213 DDQLIKIFRLMGTPNERTWPGVSS 236
>sp|P97377|CDK2_MOUSE Cyclin-dependent kinase 2 OS=Mus musculus
OX=10090 GN=Cdk2 PE=1 SV=2
Length=346
Score = 208 bits (530), Expect = 2e-58, Method: Composition-based stats.
Identities = 61/206 (30%), Positives = 102/206 (50%), Gaps = 15/206 (7%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+
Sbjct 1 MENFQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICE 1009
L H +I+K E L LV E++ L+ ++ I L + + Q+ +
Sbjct 57 ELNHPNIVKLLDVI--HTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQ 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
G+A+ H+ +HRDL +N+L++ + +K+ DFGLA+A R +++ A
Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVP---VRTYTHEVVTLWYRA 170
Query 1070 PECLKEYKFY-YASDVWSFGVTLYEL 1094
PE L K+Y A D+WS G E+
Sbjct 171 PEILLGCKYYSTAVDIWSLGCIFAEM 196
Score = 166 bits (420), Expect = 8e-44, Method: Composition-based stats.
Identities = 45/229 (20%), Positives = 87/229 (38%), Gaps = 40/229 (17%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
+ ++ +G+GT VY+ + ++ G V LK
Sbjct 1 MENFQKVEKIGEGTYGVVYKAKNKLTGE------------------------VVALKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
LD + SL+ +++H ++ + V + +V E++ H L ++
Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-HQDLKKFMDASA 95
Query 704 -GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+P+ QL L++ + ++H ++ +N+L+ G IKL+D G+
Sbjct 96 LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEG-------SIKLADFGL 148
Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+ V + + APE L G STA+D W G E+
Sbjct 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKY-YSTAVDIWSLGCIFAEM 196
>sp|P22517|KCC2_YEAST Calcium/calmodulin-dependent protein kinase
II OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=CMK2 PE=1 SV=2
Length=447
Score = 212 bits (539), Expect = 2e-58, Method: Composition-based stats.
Identities = 67/316 (21%), Positives = 106/316 (34%), Gaps = 26/316 (8%)
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918
D+ + N V + ++ R LG G FG V
Sbjct 9 NSEFHVDVQDPERLNGHPVAKFINKLSGQPESYVNRTNYIFGRTLGAGSFGVVR----QA 64
Query 919 TNDGTGEMVAVKALKADCGPQ---HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975
T E VA+K L +E+ IL+ L H +I+ +K E + +
Sbjct 65 RKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDK--FY 122
Query 976 LVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL--- 1031
+V + G L D L R + QI + Y+H+++ +HRDL NVL
Sbjct 123 IVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDK 182
Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091
+ + I DFG+AK + + + + APE L + D+WS GV
Sbjct 183 SENSPLVIADFGIAKQLKGEEDLIYK---AAGSLGYVAPEVLTQDGHGKPCDIWSIGVIT 239
Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151
Y LL + + A +P D +V +
Sbjct 240 YTLLCGYSPFIAESVEGFMEECTASRYPVTF----------HMPYWDNISIDVKRFILKA 289
Query 1152 WETEASFRPTFENLIP 1167
+ RPT L+
Sbjct 290 LRLNPADRPTATELLD 305
Score = 159 bits (403), Expect = 2e-40, Method: Composition-based stats.
Identities = 49/299 (16%), Positives = 93/299 (31%), Gaps = 47/299 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V++ LG G+ V R V +K+
Sbjct 42 VNRTNYIFGRTLGAGSFGVV------------------------RQARKLSTNEDVAIKI 77
Query 644 LDPSHHDIA----LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
L YE S++ ++SH ++ + +VT+ G L +
Sbjct 78 LLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRI 137
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
RG + + Q+ A+ Y+ +KN+VH ++ N+L + + + + ++D
Sbjct 138 L-SRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVL----YVDKSENSPLVIAD 192
Query 760 PGVGLGALSREE----RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ E+ + ++APE L + D W G + G +P
Sbjct 193 FGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQ--DGHGKPCDIWSIGVITYTLLC-GYSPF 249
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQ-------LATLTSQCLTYEPTQRPSFRTILRDLT 867
+ S P + + L P RP+ +L D
Sbjct 250 IAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPW 308
>sp|W0LYS5|CAMKI_MACNP Calcium/calmodulin-dependent protein kinase
type 1 OS=Macrobrachium nipponense OX=159736 GN=CaMKI PE=2
SV=1
Length=345
Score = 208 bits (530), Expect = 2e-58, Method: Composition-based stats.
Identities = 64/270 (24%), Positives = 103/270 (38%), Gaps = 30/270 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G F +V L + +VA+K + + EI +LR L H +I++
Sbjct 37 LGTGAFSQVRLAEVK---EDPSRVVAIKIIDKKALKGKEDSLENEIRVLRRLQHPNIVQL 93
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021
ED+ + + L++E V G L D + + S +Q+ E + Y+H Q +H
Sbjct 94 METYEDR--EHVYLIIELVTGGELFDRIVEKGSYTEKDASDLIRQVLEAVDYMHDQGVVH 151
Query 1022 RDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
RDL N+L D D + I DFGL+K G + + APE L + +
Sbjct 152 RDLKPENLLYYSPDEDSKIMISDFGLSKMEDSG-----IMATACGTPGYVAPEVLAQKPY 206
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP- 1137
A DVWS GV Y LL + ++L+ P
Sbjct 207 GKAVDVWSIGVIAYILLCGYPPF--------------YDENDANLFAQILKGEFEFDSPY 252
Query 1138 -DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
D+ ++ + R T + +
Sbjct 253 WDEISESAKDFIRQLMCVDVEKRYTCKQAL 282
Score = 152 bits (385), Expect = 4e-39, Method: Composition-based stats.
Identities = 38/237 (16%), Positives = 76/237 (32%), Gaps = 34/237 (14%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ + LG G + V ++ + S V +K++D
Sbjct 28 EDKYILKDLLGTGAFSQVRLAEVKEDPS-----------------------RVVAIKIID 64
Query 646 PSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
++ ++ H ++ + ++ E V G L + E+G
Sbjct 65 KKALKGKEDSLENEIRVLRRLQHPNIVQLMETYEDREHVYLIIELVTGGELFDRI-VEKG 123
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ +Q+ A+ Y+ ++ +VH ++ N+L + I +SD G+
Sbjct 124 SYTEKDASDLIRQVLEAVDYMHDQGVVHRDLKPENLL----YYSPDEDSKIMISDFGLSK 179
Query 765 GALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
S ++APE L A+D W G I G P +
Sbjct 180 MEDSGIMATACGTPGYVAPEVLAQ--KPYGKAVDVWSIGVIAY-ILLCGYPPFYDEN 233
>sp|G5EEN4|GCK3_CAEEL Germinal center kinase 3 OS=Caenorhabditis
elegans OX=6239 GN=gck-3 PE=1 SV=1
Length=596
Score = 216 bits (550), Expect = 2e-58, Method: Composition-based stats.
Identities = 66/300 (22%), Positives = 111/300 (37%), Gaps = 28/300 (9%)
Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944
+D K +G G V P N E VA+K + +
Sbjct 96 NPADRWPTEPSAYKLDESIGVGATATVFTAYCLPRN----EKVAIKCINLEKCQTSVDEL 151
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------- 994
EI + H +++ Y Q E L +VM + GS+ D L R
Sbjct 152 SHEIQAMSQCNHPNVVSYYTSFIAQEE--LWVVMRLLNCGSMLDILKRKVKAIGKEQAQF 209
Query 995 --IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
+ + +++ +G+ Y H IHRD+ A N+LL +D ++I DFG++ +
Sbjct 210 GVLDEVSIATVLREVLKGLEYFHLNGQIHRDIKAGNILLADDGTIQIADFGVSGWLASSG 269
Query 1053 ---EYYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108
+VR W APE +++ + + +D+WS G+ EL T P
Sbjct 270 GDLSRQKVRHTFVGTPCWMAPEVMEQVQGYDFKADIWSLGILAIELATGTAPYHKYP-PM 328
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
L+ Q L ER + L+++C + + + RPT L+
Sbjct 329 KVLMLTLQNDPPTLET-----NAERKDQYKAYGKSFKTLIRDCLQKDPAKRPTASELLKY 383
Score = 153 bits (386), Expect = 2e-37, Method: Composition-based stats.
Identities = 47/264 (18%), Positives = 87/264 (33%), Gaps = 43/264 (16%)
Query 638 RVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696
+V +K ++ + MSQ +H ++ + + E +V + G +
Sbjct 133 KVAIKCINLEKCQTSVDELSHEIQAMSQCNHPNVVSYYTSFIAQEELWVVMRLLNCGSML 192
Query 697 VWLRR----------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746
L+R + G + V +++ L Y +H ++ NILLA G
Sbjct 193 DILKRKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEYFHLNGQIHRDIKAGNILLADDG 252
Query 747 LAEGTSPFIKLSDPG-----------VGLGALSREERVERIPWLAPECLPGGANSLSTAM 795
I+++D G + + R V W+APE +
Sbjct 253 -------TIQIADFGVSGWLASSGGDLSRQKV-RHTFVGTPCWMAPEVMEQ-VQGYDFKA 303
Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-----------QHRLPEPSCPQLATL 844
D W G +E+ G AP P + + + + TL
Sbjct 304 DIWSLGILAIELA-TGTAPYHKYPPMKVLMLTLQNDPPTLETNAERKDQYKAYGKSFKTL 362
Query 845 TSQCLTYEPTQRPSFRTILRDLTR 868
CL +P +RP+ +L+
Sbjct 363 IRDCLQKDPAKRPTASELLKYSFF 386
>sp|Q9Y2K2|SIK3_HUMAN Serine/threonine-protein kinase SIK3 OS=Homo
sapiens OX=9606 GN=SIK3 PE=1 SV=4
Length=1321
Score = 224 bits (572), Expect = 2e-58, Method: Composition-based stats.
Identities = 71/293 (24%), Positives = 120/293 (41%), Gaps = 29/293 (10%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADC 936
P + P Y + R +G+G+F V T+ T VA+K + K
Sbjct 47 QPRPPAPASRGPMPARIGYYEIDRTIGKGNFAVVK----RATHLVTKAKVAIKIIDKTQL 102
Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SI 995
++ +E+ I++ L H HII+ E E+ + LV EY G + D+L H +
Sbjct 103 DEENLKKIFREVQIMKMLCHPHIIRLYQVME--TERMIYLVTEYASGGEIFDHLVAHGRM 160
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
+ +QI + + H ++ +HRDL A N+LLD + +KI DFG + G
Sbjct 161 AEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPG---Q 217
Query 1056 RVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
++ SP + APE + ++ D+WS GV LY L+
Sbjct 218 LLKTWCGSPP-YAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFD------------ 264
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
T+ L + G + P E HL+++ + + R + E +
Sbjct 265 ---GSTLQNLRARVLSG-KFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICK 313
Score = 176 bits (447), Expect = 2e-43, Method: Composition-based stats.
Identities = 52/292 (18%), Positives = 95/292 (33%), Gaps = 42/292 (14%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
R+ EI +G+G V V + +V +K
Sbjct 62 RIGYYEID--RTIGKGNFAVVKRATHLV------------------------TKAKVAIK 95
Query 643 VLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
++D + + + +M + H H+ ++ V +VTEY G + L
Sbjct 96 IIDKTQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLV 155
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G + +Q+ +A+ + +N+VH ++ N+LL + IK++D
Sbjct 156 AH-GRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLD-------ANLNIKIADF 207
Query 761 GVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
G + P+ APE G +D W G L + G P
Sbjct 208 GFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYD-GPKVDIWSLGVVLY-VLVCGALPFDG 265
Query 818 RSPSEKE-HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ + R+P + L L +P +R S I +
Sbjct 266 STLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWM 317
>sp|P11440|CDK1_MOUSE Cyclin-dependent kinase 1 OS=Mus musculus
OX=10090 GN=Cdk1 PE=1 SV=3
Length=297
Score = 206 bits (525), Expect = 2e-58, Method: Composition-based stats.
Identities = 66/307 (21%), Positives = 124/307 (40%), Gaps = 38/307 (12%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+
Sbjct 1 MEDYIKIEKIGEGTYGVV----YKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQIC 1008
L H +I+ + + L L+ E++ + L+ YL P + + + + QI
Sbjct 57 ELRHPNIVSLQDVLMQ--DSRLYLIFEFLSM-DLKKYLDSIPPGQFMDSSLVKSYLHQIL 113
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+G+ + H++ +HRDL +N+L+D+ +K+ DFGLA+A RV +++
Sbjct 114 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP---IRVYTHEVVTLWYR 170
Query 1069 APECLKEY-KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
+PE L ++ D+WS G EL T +
Sbjct 171 SPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPE 230
Query 1128 LE--RGERLPRPDKCPCEVY-----------HLMKNCWETEASFR---------PTFENL 1165
+E + + P P + L+ + + R P F++L
Sbjct 231 VESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDL 290
Query 1166 IPILKTV 1172
+K +
Sbjct 291 DNQIKKM 297
Score = 164 bits (414), Expect = 1e-43, Method: Composition-based stats.
Identities = 43/267 (16%), Positives = 94/267 (35%), Gaps = 41/267 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ ++ +G+GT VY+GR RV G V +K +
Sbjct 1 MEDYIKIEKIGEGTYGVVYKGRHRVTGQ------------------------IVAMKKIR 36
Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702
+ + SL+ ++ H ++ + V ++ ++ E++ L +L
Sbjct 37 LESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95
Query 703 RGHV-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
G + Q+ + + ++ ++H ++ +N+L+ G IKL+D G
Sbjct 96 PGQFMDSSLVKSYLHQILQGIVFCHSRRVLHRDLKPQNLLIDDKG-------TIKLADFG 148
Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ V + + +PE L G+ ST +D W G E+
Sbjct 149 LARAFGIPIRVYTHEVVTLWYRSPEVLL-GSARYSTPVDIWSIGTIFAELATKKPLFHGD 207
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ P++ +L
Sbjct 208 SEIDQLFRIFRALGTPNNEVWPEVESL 234
>sp|P51958|CDK1_CARAU Cyclin-dependent kinase 1 OS=Carassius auratus
OX=7957 GN=cdk1 PE=1 SV=1
Length=302
Score = 207 bits (526), Expect = 2e-58, Method: Composition-based stats.
Identities = 64/282 (23%), Positives = 110/282 (39%), Gaps = 29/282 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHII 960
+GEG +G V Y N TG++VA+K ++ + + S +EI +L+ L H +++
Sbjct 9 KIGEGTYGVV----YKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHPNVV 64
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA 1016
+ E L LV E++ + L+ YL + + + QI EG+ + H
Sbjct 65 RLLDVLMQ--ESKLYLVFEFLSM-DLKKYLDSIPSGQFMDPMLVKSYLYQILEGILFCHC 121
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE- 1075
+ +HRDL +N+L+DN ++K+ DFGLA+A RV +++ APE L
Sbjct 122 RRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVP---VRVYTHEVVTLWYRAPEVLLGA 178
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE--RGER 1133
++ DVWS G EL T + +E +
Sbjct 179 SRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNEVWPDVESLPDYK 238
Query 1134 LPRPDKCPCEVY-----------HLMKNCWETEASFRPTFEN 1164
P + L+ + R +
Sbjct 239 NTFPKWKSGNLASTVKNLDKNGIDLLTKMLIYDPPKRISARQ 280
Score = 166 bits (421), Expect = 2e-44, Method: Composition-based stats.
Identities = 44/267 (16%), Positives = 93/267 (35%), Gaps = 41/267 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ ++ +G+GT VY+GR + G V +K +
Sbjct 1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQ------------------------VVAMKKIR 36
Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702
+ + SL+ ++ H ++ + V ++ + +V E++ L +L
Sbjct 37 LESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSM-DLKKYLDSIP 95
Query 703 RGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
G + Q+ + + + ++H ++ +N+L+ G+ IKL+D G
Sbjct 96 SGQFMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLIDNKGV-------IKLADFG 148
Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ V + + APE L GA+ ST +D W G E+
Sbjct 149 LARAFGVPVRVYTHEVVTLWYRAPEVLL-GASRYSTPVDVWSIGTIFAELATKKPLFHGD 207
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ P + +L
Sbjct 208 SEIDQLFRIFRTLGTPNNEVWPDVESL 234
>sp|Q7XQP4|SAPK7_ORYSJ Serine/threonine-protein kinase SAPK7 OS=Oryza
sativa subsp. japonica OX=39947 GN=SAPK7 PE=2 SV=2
Length=359
Score = 209 bits (531), Expect = 2e-58, Method: Composition-based stats.
Identities = 69/268 (26%), Positives = 105/268 (39%), Gaps = 26/268 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
D+G G+FG L N T E+VA+K + G + +EI R+L H +II+
Sbjct 9 DIGAGNFGVARLM----RNKETKELVAMKYIPR--GLKIDENVAREIINHRSLRHPNIIR 62
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+K L +VMEY G L D + + F QQ+ G++Y H
Sbjct 63 FKEVVVTPTH--LAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYCHFMQIC 120
Query 1021 HRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N LLD +KI DFG +K + + + APE L ++
Sbjct 121 HRDLKLENTLLDGSPAPRLKICDFGYSK----SSLLHSKPKSTVGTPAYIAPEVLSRREY 176
Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+DVWS GVTLY +L + P I + ++ E +
Sbjct 177 DGKTADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIMSIQYKIPEYV--------- 227
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ L+ + + R T +
Sbjct 228 -HVSQDCRQLLSRIFVANPAKRITIREI 254
Score = 154 bits (389), Expect = 1e-39, Method: Composition-based stats.
Identities = 54/318 (17%), Positives = 86/318 (27%), Gaps = 41/318 (13%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ L +G G R++ + V +K +
Sbjct 1 MERYELLKDIGAGNFG------------------------VARLMRNKETKELVAMKYI- 35
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
P I + H ++ V V +V EY G L + G
Sbjct 36 PRGLKIDENVAREIINHRSLRHPNIIRFKEVVVTPTHLAIVMEYAAGGELFDRI-CNAGR 94
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
QQL +SY + H ++ N LL +P +K+ D G
Sbjct 95 FSEDEARYFFQQLICGVSYCHFMQICHRDLKLENTLLD-----GSPAPRLKICDFGYSKS 149
Query 766 AL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+L + V ++APE L T D W G TL + P
Sbjct 150 SLLHSKPKSTVGTPAYIAPEVLSRREYDGKT-ADVWSCGVTLYVMLVGAYPFEDPDDPKN 208
Query 823 KEH----FYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
Q+++PE L S+ P +R + R I L+
Sbjct 209 FRKTIGRIMSIQYKIPEYVHVSQDCRQLLSRIFVANPAKRITIREIRNHPWFLKNLPREL 268
Query 877 VLTVNPDSPASDPTVFHK 894
D +
Sbjct 269 TEAAQAMYYKKDNSAPTY 286
>sp|Q94A06|M2K1_ARATH Mitogen-activated protein kinase kinase
1 OS=Arabidopsis thaliana OX=3702 GN=MKK1 PE=1 SV=2
Length=354
Score = 209 bits (531), Expect = 2e-58, Method: Composition-based stats.
Identities = 58/287 (20%), Positives = 112/287 (39%), Gaps = 21/287 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G G V L + T + A+K ++ + QE+ I + +++
Sbjct 74 IGKGSSGNVQLV----KHKLTQQFFALKVIQLNTEESTCRAISQELRINLSSQCPYLVSC 129
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHA-QHYI 1020
G + +++E++ GSL D L + + L +++ G+ Y+H + I
Sbjct 130 YQSFYHNG--LVSIILEFMDGGSLADLLKKVGKVPENMLSAICKRVLRGLCYIHHERRII 187
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDL N+L+++ VKI DFG++K + + + +PE + +
Sbjct 188 HRDLKPSNLLINHRGEVKITDFGVSKIL---TSTSSLANSFVGTYPYMSPERISGSLYSN 244
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK- 1139
SD+WS G+ L E T P K +G +V L + + P
Sbjct 245 KSDIWSLGLVLLECATGKFPYTPPEHK--------KGWSSVYELVDAIVENPPPCAPSNL 296
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP-ILKTVHEKYQGQAPSVFS 1185
E + C + + R + + L+ + E + F+
Sbjct 297 FSPEFCSFISQCVQKDPRDRKSAKELLEHKFVKMFEDSDTNLSAYFT 343
Score = 161 bits (408), Expect = 4e-42, Method: Composition-based stats.
Identities = 53/302 (18%), Positives = 105/302 (35%), Gaps = 51/302 (17%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+++ ++ + +G+G+ NV + + + L
Sbjct 61 NQLSLADLEVIKVIGKGSSGNV------------------------QLVKHKLTQQFFAL 96
Query 642 KVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
KV+ + + A + + +L + ++ E+++ G L L+
Sbjct 97 KVIQLNTEESTCRAISQELRINLSSQCPYLVSCYQSFYHNGLVSIILEFMDGGSLADLLK 156
Query 701 RERGHVPMAWKMVVAQQLASALSYLE-NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ G VP + +++ L Y+ + ++H ++ N+L+ G +K++D
Sbjct 157 KV-GKVPENMLSAICKRVLRGLCYIHHERRIIHRDLKPSNLLINHRGE-------VKITD 208
Query 760 PGVGLGALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
GV S V P+++PE + G S D W G LLE C G+ P
Sbjct 209 FGVSKILTSTSSLANSFVGTYPYMSPERISGSL--YSNKSDIWSLGLVLLE-CATGKFPY 265
Query 816 QSRSP----SEKEHFYQRQHRLPEPS------CPQLATLTSQCLTYEPTQRPSFRTILRD 865
S P P P+ + SQC+ +P R S + +L
Sbjct 266 TPPEHKKGWSSVYELVDAIVENPPPCAPSNLFSPEFCSFISQCVQKDPRDRKSAKELLEH 325
Query 866 LT 867
Sbjct 326 KF 327
>sp|Q8C0Q4|NEK11_MOUSE Serine/threonine-protein kinase Nek11 OS=Mus
musculus OX=10090 GN=Nek11 PE=2 SV=2
Length=628
Score = 216 bits (551), Expect = 2e-58, Method: Composition-based stats.
Identities = 67/306 (22%), Positives = 120/306 (39%), Gaps = 28/306 (9%)
Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927
L+ A + P PT R + LG G FG V L G V
Sbjct 1 MLKFQETAKCVGRRPTVIPMYPTALIARRYVLQQKLGSGSFGTVYLVSDKKAKPGEELKV 60
Query 928 AVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986
+K + + P E +L L+H I+++ +Q ++ ++ EY L
Sbjct 61 -LKEISVGELNPNETVQANVEAQLLSRLHHPAIVRFHASFMEQ--ETFCIITEYCEGRDL 117
Query 987 RDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041
+ + Q++ + Q+ G+ Y+H + +HRDL ++N+ L N+ +KIGD
Sbjct 118 DYRIQEYKEAGKVFAENQIVEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNNL-LKIGD 176
Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
FG+++ + E + +PE LK + SD+WS LYE+
Sbjct 177 FGVSRLLMGSCELATTLT---GTPHYMSPEALKHQGYDAKSDIWSLACILYEMC------ 227
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ A + L + + G+ PD+ P E+ +M+ S RP+
Sbjct 228 ---------CLDHAFAGSSFLSVVLNIVEGKTPSLPDRYPRELNTIMERMLNKSPSLRPS 278
Query 1162 FENLIP 1167
+++
Sbjct 279 AADILK 284
Score = 170 bits (430), Expect = 8e-43, Method: Composition-based stats.
Identities = 55/307 (18%), Positives = 100/307 (33%), Gaps = 37/307 (12%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
LG G+ VY + + PG + + + L+P+ +
Sbjct 35 KLGSGSFGTVY----------------LVSDKKAKPGEELKVLKEISVGELNPNET---V 75
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER---GHVPMAW 710
A L+S++ H + H + ++TEY E LD ++ +
Sbjct 76 QANVEAQLLSRLHHPAIVRFHASFMEQETFCIITEYCEGRDLDYRIQEYKEAGKVFAENQ 135
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR- 769
+ QL + Y+ + ++H ++ +NI L L K+ D GV +
Sbjct 136 IVEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNNLL--------KIGDFGVSRLLMGSC 187
Query 770 ---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+++PE L D W L E+C A S S +
Sbjct 188 ELATTLTGTPHYMSPEALKH--QGYDAKSDIWSLACILYEMCCLDHAFAGSSFLSVVLNI 245
Query 827 YQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885
+ + LP+ +L T+ + L P+ RPS IL+ + L
Sbjct 246 VEGKTPSLPDRYPRELNTIMERMLNKSPSLRPSAADILKAPYMEEQLQLLMCKYPEMTLE 305
Query 886 ASDPTVF 892
+
Sbjct 306 DKNSVCQ 312
>sp|P05986|KAPC_YEAST cAMP-dependent protein kinase type 3 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=TPK3 PE=1 SV=2
Length=398
Score = 210 bits (534), Expect = 2e-58, Method: Composition-based stats.
Identities = 71/321 (22%), Positives = 121/321 (38%), Gaps = 34/321 (11%)
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901
++ +C + P + + + + ++ + + +R
Sbjct 36 HSVHEECSSNTPVEINGRNS---GKLKEEASAGICLVKKPMLQYRDTSGKYSLSDFQILR 92
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHI 959
LG G FG+V L ++ G A+K LK + E +L + H I
Sbjct 93 TLGTGSFGRVHLI----RSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFI 148
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQH 1018
I+ G +D + + +VM+Y+ G L L + +A ++C + YLH++
Sbjct 149 IRMWGTFQDS--QQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKD 206
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
I+RDL N+LLD + +KI DFG AK VP+ V + APE + +
Sbjct 207 IIYRDLKPENILLDKNGHIKITDFGFAKYVPD------VTYTLCGTPDYIAPEVVSTKPY 260
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+ D WSFGV +YE+L T+ +L L P
Sbjct 261 NKSVDWWSFGVLIYEMLAGYTPF--------------YNSNTMKTYENIL--NAELKFPP 304
Query 1139 KCPCEVYHLMKNCWETEASFR 1159
+ L+K + S R
Sbjct 305 FFHPDAQDLLKKLITRDLSER 325
Score = 176 bits (446), Expect = 1e-46, Method: Composition-based stats.
Identities = 58/322 (18%), Positives = 112/322 (35%), Gaps = 41/322 (13%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ L LG G+ V+ +R +G K + V LK ++
Sbjct 86 SDFQILRTLGTGSFGRVH--LIRSNHNGRFYALKTLK-----------KHTIVKLKQVEH 132
Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706
++ + ++S VSH + + G + MV +Y+E G L LR+ +
Sbjct 133 TNDERR--------MLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQ-RF 183
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
P A ++ AL YL +K++++ ++ NILL + G IK++D G
Sbjct 184 PNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNG-------HIKITDFGFAKYV 236
Query 767 LSREER-VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
++APE + + ++D W FG + E+ S + E+
Sbjct 237 PDVTYTLCGTPDYIAPEVVST--KPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYEN 294
Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885
+ + P P L + +T + + L LQ + +
Sbjct 295 ILNAELKFPPFFHPDAQDLLKKLITRD---------LSERLGNLQNGSEDVKNHPWFNEV 345
Query 886 ASDPTVFHKRYLKKIRDLGEGH 907
+ + + +G
Sbjct 346 IWEKLLARYIETPYEPPIQQGQ 367
>sp|Q8TGA9|HOG1_BLUGR Mitogen-activated protein kinase HOG1 OS=Blumeria
graminis OX=34373 GN=HOG1 PE=3 SV=1
Length=357
Score = 209 bits (531), Expect = 2e-58, Method: Composition-based stats.
Identities = 66/276 (24%), Positives = 107/276 (39%), Gaps = 29/276 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V ++ TG+ VAVK + K P +E+ +L+ L HE++
Sbjct 24 QPVGMGAFGLVC----SAKDNLTGQNVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENV 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIHTIASENTLRFVQ 251
Query 1127 LLERGERLPRPD---KCPCEVYHLMKNCWETEASFR 1159
L + R P D L++ + R
Sbjct 252 SLPKRVRQPLKDKFTNADPLAIGLLEEMLVFDPRRR 287
Score = 132 bits (331), Expect = 6e-32, Method: Composition-based stats.
Identities = 40/252 (16%), Positives = 81/252 (32%), Gaps = 21/252 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E D + M + +D V +K ++ P ++ Y
Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSAKDNLTGQNVAVKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLRHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
+ APE + +D W G E+ +G+ + F L
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDH--VNQFSIITELLGT 232
Query 836 PSCPQLATLTSQ 847
P + T+ S+
Sbjct 233 PPDDVIHTIASE 244
>sp|Q9FRS6|PXL1_ARATH Leucine-rich repeat receptor-like protein
kinase PXL1 OS=Arabidopsis thaliana OX=3702 GN=PXL1 PE=1 SV=1
Length=1029
Score = 223 bits (568), Expect = 2e-58, Method: Composition-based stats.
Identities = 69/296 (23%), Positives = 117/296 (40%), Gaps = 30/296 (10%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-----------SGW 944
++K+ +G G G V T VAVK L PQ+
Sbjct 713 HIKESNIIGMGAIGIVYKAEVMRRPLLT---VAVKKLWRSPSPQNDIEDHHQEEDEEDDI 769
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-----GLAQ 999
+E+++L L H +I+K G E+ + +V EY+P G+L L
Sbjct 770 LREVNLLGGLRHRNIVKILGYV--HNEREVMMVYEYMPNGNLGTALHSKDEKFLLRDWLS 827
Query 1000 LLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056
A + +G+ YLH IHRD+ + N+LLD++ +I DFGLAK + +E
Sbjct 828 RYNVAVGVVQGLNYLHNDCYPPIIHRDIKSNNILLDSNLEARIADFGLAKMMLHKNETVS 887
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116
+ + APE K SD++S GV L EL+T ++++ +
Sbjct 888 M---VAGSYGYIAPEYGYTLKIDEKSDIYSLGVVLLELVTGKMPIDPSFEDSIDVVEWIR 944
Query 1117 GQMTVLR-LTELLERGERLPRPDKCPCEV--YHLMKNCWETEASFRPTFENLIPIL 1169
++ L E+++ + + C RP+ ++I +L
Sbjct 945 RKVKKNESLEEVIDASIAGDCKHVIEEMLLALRIALLCTAKLPKDRPSIRDVITML 1000
Score = 180 bits (456), Expect = 1e-44, Method: Composition-based stats.
Identities = 50/274 (18%), Positives = 93/274 (34%), Gaps = 55/274 (20%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-- 644
I + + +G G VY+ + R L V +K L
Sbjct 712 SHIKESNIIGMGAIGIVYKAEV-----------------------MRRPLLTVAVKKLWR 748
Query 645 DPSHHD----------IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694
PS + +L+ + H ++ + G E +MV EY+ +G
Sbjct 749 SPSPQNDIEDHHQEEDEEDDILREVNLLGGLRHRNIVKILGYVHNEREVMMVYEYMPNGN 808
Query 695 LDVWLRRERGHV---PMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748
L L + + VA + L+YL N ++H ++ NILL
Sbjct 809 LGTALHSKDEKFLLRDWLSRYNVAVGVVQGLNYLHNDCYPPIIHRDIKSNNILLD----- 863
Query 749 EGTSPFIKLSDPGVGLGALSREERV----ERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
++ +++D G+ L + E V ++APE G + D + G L
Sbjct 864 --SNLEARIADFGLAKMMLHKNETVSMVAGSYGYIAPEY--GYTLKIDEKSDIYSLGVVL 919
Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838
LE+ G+ P+ + + ++ +
Sbjct 920 LELV-TGKMPIDPSFEDSIDVVEWIRRKVKKNES 952
>sp|Q9SMQ4|SRK2F_ARATH Serine/threonine-protein kinase SRK2F OS=Arabidopsis
thaliana OX=3702 GN=SRK2F PE=1 SV=1
Length=350
Score = 208 bits (530), Expect = 2e-58, Method: Composition-based stats.
Identities = 71/276 (26%), Positives = 111/276 (40%), Gaps = 26/276 (9%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+RDLG G+FG L GE AVK + + G + ++EI R
Sbjct 1 MERYDILRDLGSGNFGVAKLV----REKANGEFYAVKYI--ERGLKIDEHVQREIINHRD 54
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMA 1012
L H +II++K L +VMEY G L + + + + +Q+ G++
Sbjct 55 LKHPNIIRFKEVFVTPTH--LAIVMEYAAGGELFERICNAGRFSEDEGRYYFKQLISGVS 112
Query 1013 YLHAQHYIHRDLAARNVLLDN--DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
Y HA HRDL N LLD +KI DFG +K + + + +P + AP
Sbjct 113 YCHAMQICHRDLKLENTLLDGSPSSHLKICDFGYSK---SSVLHSQPKSTVGTPA-YVAP 168
Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E L ++ +DVWS GVTLY +L + P + + +L
Sbjct 169 EVLSRKEYNGKIADVWSCGVTLYVMLVGAYPFEDPED----------PRNIRNTIQRILS 218
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+P + E HL+ + + R T +
Sbjct 219 VHYTIPDYVRISSECKHLLSRIFVADPDKRITVPEI 254
Score = 147 bits (370), Expect = 4e-37, Method: Composition-based stats.
Identities = 52/327 (16%), Positives = 100/327 (31%), Gaps = 41/327 (13%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ L LG G V + +R + +G+ +K ++
Sbjct 1 MERYDILRDLGSGNFG-VAK-LVREKANGEFY----------------------AVKYIE 36
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
I + H ++ V V +V EY G L + G
Sbjct 37 RG-LKIDEHVQREIINHRDLKHPNIIRFKEVFVTPTHLAIVMEYAAGGELFERI-CNAGR 94
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+QL S +SY + H ++ N LL S +K+ D G
Sbjct 95 FSEDEGRYYFKQLISGVSYCHAMQICHRDLKLENTLLD-----GSPSSHLKICDFGYSKS 149
Query 766 AL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
++ + V ++APE L + D W G TL + P
Sbjct 150 SVLHSQPKSTVGTPAYVAPEVLSRKEYN-GKIADVWSCGVTLYVMLVGAYPFEDPEDPRN 208
Query 823 KEHFYQR----QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
+ QR + +P+ + L S+ +P +R + I + L+ +
Sbjct 209 IRNTIQRILSVHYTIPDYVRISSECKHLLSRIFVADPDKRITVPEIEKHPWFLKGPLVVP 268
Query 877 VLTVNPDSPASDPTVFHKRYLKKIRDL 903
D+ + ++ + + ++
Sbjct 269 PEEEKCDNGVEEEEEEEEKCRQSVEEI 295
>sp|Q60DG4|NEK4_ORYSJ Serine/threonine-protein kinase Nek4 OS=Oryza
sativa subsp. japonica OX=39947 GN=NEK4 PE=2 SV=1
Length=943
Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats.
Identities = 61/282 (22%), Positives = 116/282 (41%), Gaps = 28/282 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEI 948
+ + +G G FG L + +K ++ A + R QE+
Sbjct 1 MESRMDQYEIMEQVGRGAFGAAILVNHKIERK----KYVLKKIRLARQTERCRKSAHQEM 56
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQ 1005
++ L H +I+++K ++G + +V Y G + + + + + +LL +
Sbjct 57 ALIARLQHPYIVEFKEAWVEKG-CYVCIVTGYCEGGDMDELMKKLNGTYFPEEKLLKWFA 115
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
Q+ + YLH+ + +HRDL N+ L D+ +++GDFGLAK + E +
Sbjct 116 QLVLAVDYLHSNYVLHRDLKCSNIFLTKDQDIRLGDFGLAKTLKEDD----LTSSVVGTP 171
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+ PE L + + + SD+WS G +YE+ ++ P K ++ G L
Sbjct 172 NYMCPELLTDIPYGFKSDIWSLGCCMYEM-----AAHRPAFKAFDMAG----------LI 216
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ R P P + L+K+ RPT ++
Sbjct 217 SKINRSSIGPLPACYSSSMKTLIKSMLRKSPEHRPTASEILK 258
Score = 145 bits (367), Expect = 4e-34, Method: Composition-based stats.
Identities = 56/327 (17%), Positives = 104/327 (32%), Gaps = 41/327 (13%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
R+DQ EI + +G+G ++ ++ V+ K
Sbjct 4 RMDQYEI--MEQVGRGAFG-----------------------AAILVNHKIERKKYVLKK 38
Query 643 -VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLR 700
L + ++ +L++++ H ++ V +VT Y E G +D ++
Sbjct 39 IRLARQTERCRKSAHQEMALIARLQHPYIVEFKEAWVEKGCYVCIVTGYCEGGDMDELMK 98
Query 701 RERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ G + P + QL A+ YL + ++H ++ NI L + I+L D
Sbjct 99 KLNGTYFPEEKLLKWFAQLVLAVDYLHSNYVLHRDLKCSNIFLTK-------DQDIRLGD 151
Query 760 PGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL- 815
G+ + V ++ PE L D W G + E+ A
Sbjct 152 FGLAKTLKEDDLTSSVVGTPNYMCPELLTDIPYGF--KSDIWSLGCCMYEMAAHRPAFKA 209
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+ + LP + TL L P RP+ IL++ N
Sbjct 210 FDMAGLISKINRSSIGPLPACYSSSMKTLIKSMLRKSPEHRPTASEILKNPYLQPYVNQC 269
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRD 902
L+ P +
Sbjct 270 RPLSDAPTPIRMPEKPLSTSRSNQRCT 296
>sp|Q0VD22|STK33_BOVIN Serine/threonine-protein kinase 33 OS=Bos
taurus OX=9913 GN=STK33 PE=2 SV=1
Length=486
Score = 213 bits (541), Expect = 2e-58, Method: Composition-based stats.
Identities = 69/325 (21%), Positives = 124/325 (38%), Gaps = 31/325 (10%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
PS + + Q + D + R LG+G FG V
Sbjct 73 KDSPSKSSNIERKPSQQQWGRGNFTEGKVPHIRMDNGAALQEIYTFGRILGQGSFGMV-- 130
Query 914 YCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972
+ + A+K + + G ++E+DIL+++ HEHII + E K
Sbjct 131 --IEAIDKERETKWAIKKVNKEKAGSSAVKLLEREVDILKSVKHEHIIHLEQVFE--TPK 186
Query 973 SLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031
+ LVME G L++ L R + Q + +AYLH + +HRDL N+++
Sbjct 187 KMYLVMELCEDGELKEILERKGHFSENETRWIIQSLASAIAYLHNKDIVHRDLKLENIMV 246
Query 1032 DN---------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082
+ + +K+ DFGLA G ++ +P+ + APE + + +
Sbjct 247 KSSFIDANNEMNLNIKVTDFGLA-VKKHGRSEVMLQTTCGTPI-YMAPEVINAHDYSQQC 304
Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
D+WS GV +Y LL +A + + L + E + +
Sbjct 305 DIWSIGVIMYILLCGKAPF------------MASSEEKLFELIKKGELHFKNSIWNSISD 352
Query 1143 EVYHLMKNCWETEASFRPTFENLIP 1167
++K + + + R T + L+
Sbjct 353 CAKSVLKQLMKVDPAHRITAKELLD 377
Score = 186 bits (473), Expect = 2e-49, Method: Composition-based stats.
Identities = 58/292 (20%), Positives = 107/292 (37%), Gaps = 42/292 (14%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH- 648
T LGQG+ V E D+ +E + +K ++
Sbjct 117 TFGRILGQGSFGMVIEAI------------------------DKERETKWAIKKVNKEKA 152
Query 649 -HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
++ V H H+ + V + +V E E G L L R +GH
Sbjct 153 GSSAVKLLEREVDILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILER-KGHFS 211
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG--TSPFIKLSDPGVGLG 765
+ Q LASA++YL NK++VH ++ NI++ + + IK++D G+ +
Sbjct 212 ENETRWIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDANNEMNLNIKVTDFGLAVK 271
Query 766 ALSRE-----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
R ++APE + A+ S D W G + I G+AP + S
Sbjct 272 KHGRSEVMLQTTCGTPIYMAPEVI--NAHDYSQQCDIWSIGVIMY-ILLCGKAPFMASSE 328
Query 821 SEKEHFYQRQ-----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ ++ + + ++ Q + +P R + + +L +
Sbjct 329 EKLFELIKKGELHFKNSIWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQW 380
>sp|P21860|ERBB3_HUMAN Receptor tyrosine-protein kinase erbB-3
OS=Homo sapiens OX=9606 GN=ERBB3 PE=1 SV=1
Length=1342
Score = 224 bits (571), Expect = 2e-58, Method: Composition-based stats.
Identities = 90/272 (33%), Positives = 139/272 (51%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + V +K ++ G Q + + +L H HI++
Sbjct 715 LGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRL 774
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C SLQLV +Y+PLGSL D++ +H +G LL + QI +GM YL +
Sbjct 775 LGLC---PGSSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMV 831
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HR+LAARNVLL + V++ DFG+A +P + + + +P+ W A E + K+ +
Sbjct 832 HRNLAARNVLLKSPSQVQVADFGVADLLPP-DDKQLLYSEAKTPIKWMALESIHFGKYTH 890
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + + + +LLE+GERL +P C
Sbjct 891 QSDVWSYGVTVWELMTFG--------------AEPYAGLRLAEVPDLLEKGERLAQPQIC 936
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW + + RPTF+ L +
Sbjct 937 TIDVYMVMVKCWMIDENIRPTFKELANEFTRM 968
Score = 206 bits (525), Expect = 8e-53, Method: Composition-based stats.
Identities = 72/376 (19%), Positives = 136/376 (36%), Gaps = 39/376 (10%)
Query 510 QDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARA 569
VL G ++ + + ++ G + R + L
Sbjct 630 LGQTLVLIGKTHLTMALTVIAGLVVIFMMLGGTFLYWRGRRIQNKRAMRRYLERGESIEP 689
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+ +++ + E+ +L LG G V++G EG
Sbjct 690 LDPSEKANKVLARIFKETELRKLKVLGSGVFGTVHKGVWIPEGESI-------------- 735
Query 630 GRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ V +KV+ D S A + + + H H+ + G+C G +VT+
Sbjct 736 ------KIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCP-GSSLQLVTQ 788
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
Y+ G L +R+ RG + + Q+A + YLE +VH N+ RN+LL
Sbjct 789 YLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLL------ 842
Query 749 EGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+ ++++D GV + E I W+A E + G + D W +G
Sbjct 843 -KSPSQVQVADFGVADLLPPDDKQLLYSEAKTPIKWMALESIHFG--KYTHQSDVWSYGV 899
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860
T+ E+ G P +E ++ RL P+ + + +C + RP+F+
Sbjct 900 TVWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFK 959
Query 861 TILRDLTRLQPHNLAD 876
+ + TR+
Sbjct 960 ELANEFTRMARDPPRY 975
>sp|P97477|AURKA_MOUSE Aurora kinase A OS=Mus musculus OX=10090
GN=Aurka PE=1 SV=1
Length=395
Score = 210 bits (534), Expect = 2e-58, Method: Composition-based stats.
Identities = 65/296 (22%), Positives = 110/296 (37%), Gaps = 33/296 (11%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRS-GWKQEI 948
+ R LG+G FG V L + ++A+K L K + ++E+
Sbjct 118 QWTLEDFDIGRPLGKGKFGNVYL----ARERQSKFILALKVLFKTQLEKANVEHQLRREV 173
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQI 1007
+I L H +I++ G D + L++EY PLG++ L + + + ++
Sbjct 174 EIQSHLRHPNILRLYGYFHDAT--RVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 231
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
++Y H++ IHRD+ N+LL ++ +KI DFG + P R + +
Sbjct 232 ANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSR-----RTTMCGTLDY 286
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
PE ++ D+WS GV YE L + A R
Sbjct 287 LPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFE------------AHTYQETYRRISR 334
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183
+E PD L+ + AS R T + L+ K P
Sbjct 335 VE----FTFPDFVTEGARDLISRLLKHNASQRLTLAEV---LEHPWIKANSSKPPT 383
Score = 179 bits (455), Expect = 6e-48, Method: Composition-based stats.
Identities = 59/326 (18%), Positives = 111/326 (34%), Gaps = 41/326 (13%)
Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607
R PQ E + + ++ LG+G NVY
Sbjct 83 SRLNNPQKNEQPAASGNDSEKEQASLQKTEDTKKRQWTLEDFDIGRPLGKGKFGNVYLA- 141
Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETASLMSQ 664
R+R + + LKVL + ++ + S
Sbjct 142 -----------------------RERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSH 178
Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724
+ H ++ ++G ++ EY G + L++ +LA+ALSY
Sbjct 179 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKL-SKFDEQRTATYITELANALSY 237
Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--REERVERIPWLAPE 782
+K ++H ++ N+LL G++ +K++D G + A S R + +L PE
Sbjct 238 CHSKRVIHRDIKPENLLL-------GSNGELKIADFGWSVHAPSSRRTTMCGTLDYLPPE 290
Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQL 841
+ G + +D W G E G P ++ + E + + P+
Sbjct 291 MIEGRMH--DEKVDLWSLGVLCYEFLV-GMPPFEAHTYQETYRRISRVEFTFPDFVTEGA 347
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLT 867
L S+ L + +QR + +L
Sbjct 348 RDLISRLLKHNASQRLTLAEVLEHPW 373
>sp|Q9WUA6|AKT3_MOUSE RAC-gamma serine/threonine-protein kinase
OS=Mus musculus OX=10090 GN=Akt3 PE=1 SV=1
Length=479
Score = 213 bits (541), Expect = 2e-58, Method: Composition-based stats.
Identities = 75/374 (20%), Positives = 129/374 (34%), Gaps = 51/374 (14%)
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTY-------------------- 851
E P P +F + +L + P+ T +CL +
Sbjct 40 EKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWT 99
Query 852 ---EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
+ R + + ++ D+ + ++ LG+G F
Sbjct 100 EAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTF 159
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCC 966
GKV L +G+ A+K LK + + E +L+ H + K
Sbjct 160 GKVILV----REKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSF 215
Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
Q + L VMEYV G L +L R + + +I + YLH+ ++RDL
Sbjct 216 --QTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLK 273
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
N++LD D +KI DFGL K EG + + APE L++ + A D W
Sbjct 274 LENLMLDKDGHIKITDFGLCK---EGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWW 330
Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
GV +YE++ + Q + L + + + P +
Sbjct 331 GLGVVMYEMMCGRLPFYN------------QDHEKLFELILMED----IKFPRTLSSDAK 374
Query 1146 HLMKNCWETEASFR 1159
L+ + + R
Sbjct 375 SLLSGLLIKDPNKR 388
Score = 163 bits (413), Expect = 1e-41, Method: Composition-based stats.
Identities = 56/293 (19%), Positives = 96/293 (33%), Gaps = 43/293 (15%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
++ S R + L LG+GT V + R
Sbjct 131 EEMDASTTHHKRKTMNDFDYLKLLGKGTFGKV------------------------ILVR 166
Query 632 DRGQELRVVLKVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ +K+L + ++ H L + V E
Sbjct 167 EKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVME 226
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
YV G L L RER ++ SAL YL + +V+ ++ N++L + G
Sbjct 227 YVNGGELFFHLSRER-VFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDG-- 283
Query 749 EGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
IK++D G+ ++ + +LAPE L N A+D WG G +
Sbjct 284 -----HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLED--NDYGRAVDWWGLGVVM 336
Query 805 LEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
E+ G P ++ + + P +L S L +P +R
Sbjct 337 YEMMC-GRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKR 388
>sp|P23111|CDC2_MAIZE Cell division control protein 2 homolog
OS=Zea mays OX=4577 GN=CDC2 PE=2 SV=1
Length=294
Score = 206 bits (525), Expect = 2e-58, Method: Composition-based stats.
Identities = 72/295 (24%), Positives = 124/295 (42%), Gaps = 33/295 (11%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+
Sbjct 1 MEQYEKVEKIGEGTYGVV----YKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009
+ H +I++ EK + LV EY+ L L+ ++ P + + + QI
Sbjct 57 EMNHGNIVRLHDVV--HSEKRIYLVFEYLDL-DLKKFMDSCPEFAKNPTLIKSYLYQILH 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
G+AY H+ +HRDL +N+L+D +K+ DFGLA+A R +++
Sbjct 114 GVAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIP---VRTFTHEVVTLWYR 170
Query 1069 APECLKE-YKFYYASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIGIAQGQMTVL 1122
APE L ++ DVWS G E++ DS K ++G Q +
Sbjct 171 APEILLGARQYSTPVDVWSVGCIFAEMVNQKPLFPGDSEIDELFKIFRILGTPNEQ-SWP 229
Query 1123 RLTELLERGERLPR----------PDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
++ L + PR P+ P + L+ E S R T +
Sbjct 230 GVSCLPDFKTAFPRWQAQDLATVVPNLDPAGL-DLLSKMLRYEPSKRITARQALE 283
Score = 159 bits (402), Expect = 6e-42, Method: Composition-based stats.
Identities = 47/266 (18%), Positives = 93/266 (35%), Gaps = 39/266 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
++ ++ +G+GT VY+ D+ + LK
Sbjct 1 MEQYEKVEKIGEGTYGVVYKAL------------------------DKATNETIALKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702
L+ + SL+ +++H ++ +H V +V EY++ L ++
Sbjct 37 LEQEDEGVPSTAIREISLLKEMNHGNIVRLHDVVHSEKRIYLVFEYLDL-DLKKFMDSCP 95
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
Q+ ++Y + ++H ++ +N+L+ R A +KL+D G+
Sbjct 96 EFAKNPTLIKSYLYQILHGVAYCHSHRVLHRDLKPQNLLIDRRTNA------LKLADFGL 149
Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + + APE L GA ST +D W G E+
Sbjct 150 ARAFGIPVRTFTHEVVTLWYRAPEILL-GARQYSTPVDVWSVGCIFAEMVNQKPLFPGDS 208
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844
E ++ E S P ++ L
Sbjct 209 EIDELFKIFRILGTPNEQSWPGVSCL 234
>sp|Q9FF31|LRL21_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE
PROTEIN KINASE-like 2.1 OS=Arabidopsis thaliana
OX=3702 GN=LRK10L-2.1 PE=3 SV=1
Length=638
Score = 217 bits (552), Expect = 2e-58, Method: Composition-based stats.
Identities = 65/289 (22%), Positives = 115/289 (40%), Gaps = 33/289 (11%)
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
LG+G FG V N G VAVK LK + E+ + H +
Sbjct 323 FSHTLGKGGFGTVYGG-----NLCDGRKVAVKILKDFKSNG--EDFINEVASMSQTSHVN 375
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLH 1015
I+ G C + +++ +V E++ GSL +L + ++ L A + G+ YLH
Sbjct 376 IVSLLGFCYEGSKRA--IVYEFLENGSLDQFLSEKKSLNLDVSTLYRIALGVARGLDYLH 433
Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+H D+ +N+LLD+ K+ DFGLAK E E D + + APE
Sbjct 434 HGCKTRIVHFDIKPQNILLDDTFCPKVSDFGLAKLC-EKRESILSLLDARGTIGYIAPEV 492
Query 1073 LKE--YKFYYASDVWSFGVTLYELL---------THCDSSQSPPTKFLELIGIAQGQMTV 1121
+ + SDV+S+G+ + E++ T +S S + G+ T
Sbjct 493 FSGMYGRVSHKSDVYSYGMLVLEMIGAKNKEIEETAASNSSSAYFPDWIYKNLENGEDTW 552
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
E+ + + ++ + C + RP ++ +++
Sbjct 553 KFGDEISREDK------EVAKKMTLVGLWCIQPSPLNRPPMNRIVEMME 595
Score = 212 bits (540), Expect = 6e-57, Method: Composition-based stats.
Identities = 65/322 (20%), Positives = 112/322 (35%), Gaps = 62/322 (19%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
+ L Q S+ V + LG+G VY G L
Sbjct 306 VQLKQYSYAEVRKITKLFSHTLGKGGFGTVYGGNLCDGR--------------------- 344
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+V +K+L + F + MSQ SH ++ + G C G + +V E++E+G
Sbjct 345 ----KVAVKILKDFKSNG-EDFINEVASMSQTSHVNIVSLLGFCYEGSKRAIVYEFLENG 399
Query 694 PLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAE 749
LD +L ++ ++ ++ +A +A L YL + +VH ++ +NILL
Sbjct 400 SLDQFLSEKKSLNLDVSTLYRIALGVARGLDYLHHGCKTRIVHFDIKPQNILLDDTFCP- 458
Query 750 GTSPFIKLSDPGVGLGALSREERV------ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
K+SD G+ RE + I ++APE G +S D + +G
Sbjct 459 ------KVSDFGLAKLCEKRESILSLLDARGTIGYIAPEVFSGMYGRVSHKSDVYSYGML 512
Query 804 LLEIC---------------FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLT--- 845
+LE+ P E + ++A
Sbjct 513 VLEMIGAKNKEIEETAASNSSSAYFPDWIYKNLENGEDTWKFGDEISREDKEVAKKMTLV 572
Query 846 -SQCLTYEPTQRPSFRTILRDL 866
C+ P RP I+ +
Sbjct 573 GLWCIQPSPLNRPPMNRIVEMM 594
>sp|Q9Y243|AKT3_HUMAN RAC-gamma serine/threonine-protein kinase
OS=Homo sapiens OX=9606 GN=AKT3 PE=1 SV=1
Length=479
Score = 212 bits (540), Expect = 2e-58, Method: Composition-based stats.
Identities = 75/374 (20%), Positives = 129/374 (34%), Gaps = 51/374 (14%)
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTY-------------------- 851
E P P +F + +L + P+ T +CL +
Sbjct 40 EKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWT 99
Query 852 ---EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
+ R + + ++ D+ + ++ LG+G F
Sbjct 100 EAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTF 159
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCC 966
GKV L +G+ A+K LK + + E +L+ H + K
Sbjct 160 GKVILV----REKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSF 215
Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
Q + L VMEYV G L +L R + + +I + YLH+ ++RDL
Sbjct 216 --QTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLK 273
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
N++LD D +KI DFGL K EG + + APE L++ + A D W
Sbjct 274 LENLMLDKDGHIKITDFGLCK---EGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWW 330
Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
GV +YE++ + Q + L + + + P +
Sbjct 331 GLGVVMYEMMCGRLPFYN------------QDHEKLFELILMED----IKFPRTLSSDAK 374
Query 1146 HLMKNCWETEASFR 1159
L+ + + R
Sbjct 375 SLLSGLLIKDPNKR 388
Score = 163 bits (413), Expect = 1e-41, Method: Composition-based stats.
Identities = 56/293 (19%), Positives = 96/293 (33%), Gaps = 43/293 (15%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
++ S R + L LG+GT V + R
Sbjct 131 EEMDASTTHHKRKTMNDFDYLKLLGKGTFGKV------------------------ILVR 166
Query 632 DRGQELRVVLKVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ +K+L + ++ H L + V E
Sbjct 167 EKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVME 226
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
YV G L L RER ++ SAL YL + +V+ ++ N++L + G
Sbjct 227 YVNGGELFFHLSRER-VFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDG-- 283
Query 749 EGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
IK++D G+ ++ + +LAPE L N A+D WG G +
Sbjct 284 -----HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLED--NDYGRAVDWWGLGVVM 336
Query 805 LEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
E+ G P ++ + + P +L S L +P +R
Sbjct 337 YEMMC-GRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKR 388
>sp|Q5RB22|ERBB3_PONAB Receptor tyrosine-protein kinase erbB-3
OS=Pongo abelii OX=9601 GN=ERBB3 PE=2 SV=1
Length=1342
Score = 224 bits (571), Expect = 3e-58, Method: Composition-based stats.
Identities = 90/272 (33%), Positives = 139/272 (51%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + V +K ++ G Q + + +L H HI++
Sbjct 715 LGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRL 774
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C SLQLV +Y+PLGSL D++ +H +G LL + QI +GM YL +
Sbjct 775 LGLC---PGSSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMV 831
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HR+LAARNVLL + V++ DFG+A +P + + + +P+ W A E + K+ +
Sbjct 832 HRNLAARNVLLKSPSQVQVADFGVADLLPP-DDKQLLYSEAKTPIKWMALESIHFGKYTH 890
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + + + +LLE+GERL +P C
Sbjct 891 QSDVWSYGVTVWELMTFG--------------AEPYAGLRLAEVPDLLEKGERLAQPQIC 936
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW + + RPTF+ L +
Sbjct 937 TIDVYMVMVKCWMIDENIRPTFKELANEFTRM 968
Score = 206 bits (524), Expect = 1e-52, Method: Composition-based stats.
Identities = 72/376 (19%), Positives = 136/376 (36%), Gaps = 39/376 (10%)
Query 510 QDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARA 569
VL G ++ + + ++ G + R + L
Sbjct 630 LGQTLVLIGKTHLTMALTVIAGLVVIFMMLGGTFLYWRGRRIQNKRAMRRYLERGESIEP 689
Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629
+ +++ + E+ +L LG G V++G EG
Sbjct 690 LDPSEKANKVLARIFKETELKKLKVLGSGVFGTVHKGVWIPEGESI-------------- 735
Query 630 GRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ V +KV+ D S A + + + H H+ + G+C G +VT+
Sbjct 736 ------KIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCP-GSSLQLVTQ 788
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
Y+ G L +R+ RG + + Q+A + YLE +VH N+ RN+LL
Sbjct 789 YLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLL------ 842
Query 749 EGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802
+ ++++D GV + E I W+A E + G + D W +G
Sbjct 843 -KSPSQVQVADFGVADLLPPDDKQLLYSEAKTPIKWMALESIHFG--KYTHQSDVWSYGV 899
Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860
T+ E+ G P +E ++ RL P+ + + +C + RP+F+
Sbjct 900 TVWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFK 959
Query 861 TILRDLTRLQPHNLAD 876
+ + TR+
Sbjct 960 ELANEFTRMARDPPRY 975
>sp|Q63484|AKT3_RAT RAC-gamma serine/threonine-protein kinase
OS=Rattus norvegicus OX=10116 GN=Akt3 PE=2 SV=2
Length=479
Score = 212 bits (540), Expect = 3e-58, Method: Composition-based stats.
Identities = 75/374 (20%), Positives = 129/374 (34%), Gaps = 51/374 (14%)
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTY-------------------- 851
E P P +F + +L + P+ T +CL +
Sbjct 40 EKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWT 99
Query 852 ---EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
+ R + + ++ D+ + ++ LG+G F
Sbjct 100 EAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTF 159
Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCC 966
GKV L +G+ A+K LK + + E +L+ H + K
Sbjct 160 GKVILV----REKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSF 215
Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025
Q + L VMEYV G L +L R + + +I + YLH+ ++RDL
Sbjct 216 --QTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLK 273
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085
N++LD D +KI DFGL K EG + + APE L++ + A D W
Sbjct 274 LENLMLDKDGHIKITDFGLCK---EGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWW 330
Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145
GV +YE++ + Q + L + + + P +
Sbjct 331 GLGVVMYEMMCGRLPFYN------------QDHEKLFELILMED----IKFPRTLSSDAK 374
Query 1146 HLMKNCWETEASFR 1159
L+ + + R
Sbjct 375 SLLSGLLIKDPNKR 388
Score = 163 bits (412), Expect = 2e-41, Method: Composition-based stats.
Identities = 56/293 (19%), Positives = 96/293 (33%), Gaps = 43/293 (15%)
Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631
++ S R + L LG+GT V + R
Sbjct 131 EEMDASTTHHKRKTMNDFDYLKLLGKGTFGKV------------------------ILVR 166
Query 632 DRGQELRVVLKVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
++ +K+L + ++ H L + V E
Sbjct 167 EKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVME 226
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
YV G L L RER ++ SAL YL + +V+ ++ N++L + G
Sbjct 227 YVNGGELFFHLSRER-VFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDG-- 283
Query 749 EGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
IK++D G+ ++ + +LAPE L N A+D WG G +
Sbjct 284 -----HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLED--NDYGRAVDWWGLGVVM 336
Query 805 LEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
E+ G P ++ + + P +L S L +P +R
Sbjct 337 YEMMC-GRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKR 388
>sp|Q76P07|Y7165_DICDI Probable serine/threonine-protein kinase
DDB_G0277165 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0277165
PE=3 SV=1
Length=833
Score = 220 bits (561), Expect = 3e-58, Method: Composition-based stats.
Identities = 71/282 (25%), Positives = 115/282 (41%), Gaps = 31/282 (11%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC---GPQHRSGWK 945
+ + LG+G GKV L + TG V +K + + P R +
Sbjct 1 MEIHSVGPFIIGKTLGQGTTGKVKLGFHK----DTGFKVGIKIINKELLINKPSMRRKIE 56
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFA 1004
+EI +++ + H + +K E K L L++EYV G L DYL + + + L F
Sbjct 57 REIVLMKLIDHPNAMKMYEVYE--TSKYLFLILEYVEGGELFDYLVEKGGLESGEALFFF 114
Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
QQI G+ Y H+++ HRDL N+LL D+ +KI DFG+ V + +
Sbjct 115 QQIIIGLEYCHSRNICHRDLKPENLLLSGDKRIKIADFGMGSIVRKDMLLHTS----CGS 170
Query 1065 VFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
+ +PE + + +DVWS GV LY LLT + R
Sbjct 171 PHYASPEVVSGIDYDGQKADVWSCGVILYALLTGKLPFDDE---------------NIRR 215
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
L ++ G P + L+ + S R + + +
Sbjct 216 LLNKVKNGA-FSMPPYIHKDAQDLLTKMLTVDPSKRISIKEI 256
Score = 178 bits (452), Expect = 1e-44, Method: Composition-based stats.
Identities = 61/331 (18%), Positives = 112/331 (34%), Gaps = 37/331 (11%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
LGQGT V G + G ++++ K L +
Sbjct 9 FIIGKTLGQGTTGKVKLGFHKDTGFKVG--------------------IKIINKELLINK 48
Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
+ LM + H + ++ V ++ EYVE G L +L E+G +
Sbjct 49 PSMRRKIEREIVLMKLIDHPNAMKMYEVYETSKYLFLILEYVEGGELFDYL-VEKGGLES 107
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LG 765
+ QQ+ L Y ++N+ H ++ N+LL+ IK++D G+G
Sbjct 108 GEALFFFQQIIIGLEYCHSRNICHRDLKPENLLLS-------GDKRIKIADFGMGSIVRK 160
Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
+ + +PE + G D W G L + G+ P + +
Sbjct 161 DMLLHTSCGSPHYASPEVVSGIDYD-GQKADVWSCGVILYALL-TGKLPFDDENIRRLLN 218
Query 826 FYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884
+ +P L ++ LT +P++R S + I + N T +
Sbjct 219 KVKNGAFSMPPYIHKDAQDLLTKMLTVDPSKRISIKEIKEHPWFVSNFNQFQKATPVEEI 278
Query 885 PASD---PTVFHKRYLKKIRDLGEGHFGKVS 912
A + + + + LG G +V
Sbjct 279 NAEPLVDYSQIDEDIFRSLMALGVGTIDEVK 309
>sp|O01798|SPE8_CAEEL Spermatocyte protein spe-8 OS=Caenorhabditis
elegans OX=6239 GN=spe-8 PE=1 SV=2
Length=512
Score = 213 bits (542), Expect = 3e-58, Method: Composition-based stats.
Identities = 56/239 (23%), Positives = 105/239 (44%), Gaps = 34/239 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+++ +++T LG+G V++G L+ P + V +
Sbjct 210 WQLNNEQVTLNKKLGEGQFGEVHKGSLKTSVFAAP--------------------VTVAV 249
Query 642 KVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
K L +H + + F A++M +SH ++ +GVC ++V E+ + L+ L
Sbjct 250 KTLHQNHLSANEKILFLREANVMLTLSHPNVIKFYGVCTMKEPIMIVMEFCDGKSLEDAL 309
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+ V K++ A + YL K ++H ++ RN LL +K+SD
Sbjct 310 LSKEEKVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNSK-------KILKISD 362
Query 760 PGVGLGALSREERVER---IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ + ++ +ER + ++APE L G STA D + +GA + E+ DG+ P
Sbjct 363 FGLSVKGVAIKERKGGCLPVKYMAPETLKKGL--YSTASDIYSYGALMYEVYTDGKTPF 419
Score = 210 bits (535), Expect = 3e-57, Method: Composition-based stats.
Identities = 76/321 (24%), Positives = 135/321 (42%), Gaps = 20/321 (6%)
Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913
+ + H A + + + LGEG FG+V
Sbjct 174 KKYAFKSICELIAYHKRNHKPIYEGMTLICGLARHGWQLNNEQVTLNKKLGEGQFGEVHK 233
Query 914 YCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972
+ VAVK L + + + +E +++ TL H ++IK+ G C + +
Sbjct 234 GSLKTSVFAAPVTVAVKTLHQNHLSANEKILFLREANVMLTLSHPNVIKFYGVCTMK--E 291
Query 973 SLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030
+ +VME+ SL D L + +L+ G+ YLH + IHRD+AARN L
Sbjct 292 PIMIVMEFCDGKSLEDALLSKEEKVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCL 351
Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090
L++ +++KI DFGL+ E R+ G PV + APE LK+ + ASD++S+G
Sbjct 352 LNSKKILKISDFGLSVKGVAIKE----RKGGCLPVKYMAPETLKKGLYSTASDIYSYGAL 407
Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150
+YE+ T + E G+ ++ + + + + P + ++ +
Sbjct 408 MYEVYTDGKTP-------FETCGLRGNELRKAIIGKRISLAVEVELPVF----IANIFEQ 456
Query 1151 CWETEASFRPTFENLIPILKT 1171
+ E R + + +I I K
Sbjct 457 SRQYETEDRISSKQIIQIFKE 477
>sp|P48734|CDK1_BOVIN Cyclin-dependent kinase 1 OS=Bos taurus
OX=9913 GN=CDK1 PE=2 SV=2
Length=297
Score = 206 bits (524), Expect = 3e-58, Method: Composition-based stats.
Identities = 71/308 (23%), Positives = 130/308 (42%), Gaps = 40/308 (13%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+
Sbjct 1 MEDYTKIEKIGEGTYGVV----YKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQIC 1008
L H +I+ + + L L+ E++ + L+ YL P + + + + QI
Sbjct 57 ELRHPNIVSLQDVLMQ--DSRLYLIFEFLSM-DLKKYLDSIPPGQFMDSSLVKSYLYQIL 113
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+G+ + H++ +HRDL +N+L+D+ +K+ DFGLA+A RV +++
Sbjct 114 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP---IRVYTHEVVTLWYR 170
Query 1069 APECLKEY-KFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQMTVL 1122
+PE L ++ D+WS G EL T H DS + +G ++
Sbjct 171 SPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV-WP 229
Query 1123 RLTELLERGERLP--RPDKCPCEVY-------HLMKNCWETEASFR---------PTFEN 1164
+ L + P +P V L+ + + R P F +
Sbjct 230 EVESLQDYKSTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
Query 1165 LIPILKTV 1172
L +K +
Sbjct 290 LDSQIKKM 297
Score = 165 bits (417), Expect = 6e-44, Method: Composition-based stats.
Identities = 42/267 (16%), Positives = 94/267 (35%), Gaps = 41/267 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ T++ +G+GT VY+GR + G V +K +
Sbjct 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQ------------------------VVAMKKIR 36
Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702
+ + SL+ ++ H ++ + V ++ ++ E++ L +L
Sbjct 37 LESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95
Query 703 RGHV-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
G + Q+ + + ++ ++H ++ +N+L+ G IKL+D G
Sbjct 96 PGQFMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKG-------TIKLADFG 148
Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ V + + +PE L G+ ST +D W G E+
Sbjct 149 LARAFGIPIRVYTHEVVTLWYRSPEVLL-GSARYSTPVDIWSIGTIFAELATKKPLFHGD 207
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ P++ +L
Sbjct 208 SEIDQLFRIFRALGTPNNEVWPEVESL 234
>sp|Q86CS2|ATG1_DICDI Serine/threonine-protein kinase atg1 OS=Dictyostelium
discoideum OX=44689 GN=atg1 PE=3 SV=1
Length=668
Score = 217 bits (552), Expect = 3e-58, Method: Composition-based stats.
Identities = 64/269 (24%), Positives = 113/269 (42%), Gaps = 33/269 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK----ADCGPQHRSGWKQEIDILRTLYHE 957
+G G F +V Y + T E A+K + AD + EI IL+ L H
Sbjct 12 RIGWGAFAQV----YKGFSIKTNEPFAIKVVDVCRLADKNSKLTENLNYEIRILKELSHT 67
Query 958 HIIKYKGCC-EDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLH 1015
+I++ E+ + ++ME G Y+ H + + L F +Q+ G+ +L
Sbjct 68 NIVRLYDVLNEETDPTFIYMIMECCEGGDFSKYIRTHKKLTEEKALYFMKQLANGLKFLR 127
Query 1016 AQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+ +HRDL +N+LL +D +KIGDFG AK + + + + + APE
Sbjct 128 QKQIVHRDLKPQNLLLSDDSEHPILKIGDFGFAKFIDP----FSLSDTFCGSPLYMAPEI 183
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
L + +D+WS G+ LYE+L A +V L L + +
Sbjct 184 LHRKNYTVKADLWSVGIILYEMLVGEP---------------AYNSGSVPDLLNQL-QNK 227
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
++ P + +L+ + + + R +
Sbjct 228 KIKLPSHISSDCQNLIYSLLQIDVEKRIS 256
Score = 171 bits (434), Expect = 4e-43, Method: Composition-based stats.
Identities = 48/286 (17%), Positives = 94/286 (33%), Gaps = 32/286 (11%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ +G G VY+G + V + L
Sbjct 6 DYILDKRIGWGAFAQVYKGFSIKTNEPFAIK-------------------VVDVCRLADK 46
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE---NIMVTEYVEHGPLDVWLRRERG 704
+ + ++ ++SHT++ ++ V + M+ E E G ++R +
Sbjct 47 NSKLTENLNYEIRILKELSHTNIVRLYDVLNEETDPTFIYMIMECCEGGDFSKYIRTHK- 105
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + +QLA+ L +L K +VH ++ +N+LL+ + P +K+ D G
Sbjct 106 KLTEEKALYFMKQLANGLKFLRQKQIVHRDLKPQNLLLS----DDSEHPILKIGDFGFAK 161
Query 765 GALS---REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ ++APE L + + D W G L E+ A P
Sbjct 162 FIDPFSLSDTFCGSPLYMAPEILH--RKNYTVKADLWSVGIILYEMLVGEPAYNSGSVPD 219
Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
++ +LP L L + +R S+
Sbjct 220 LLNQLQNKKIKLPSHISSDCQNLIYSLLQIDVEKRISWEDFFNHKW 265
>sp|P51955|NEK2_HUMAN Serine/threonine-protein kinase Nek2 OS=Homo
sapiens OX=9606 GN=NEK2 PE=1 SV=1
Length=445
Score = 211 bits (537), Expect = 3e-58, Method: Composition-based stats.
Identities = 60/289 (21%), Positives = 108/289 (37%), Gaps = 33/289 (11%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEI 948
+ + +G G +G+ C G+++ K L + E+
Sbjct 1 MPSRAEDYEVLYTIGTGSYGR----CQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEV 56
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLF 1003
++LR L H +I++Y D+ +L +VMEY G L + R + +L
Sbjct 57 NLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRV 116
Query 1004 AQQICEGMAYLHA-----QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
Q+ + H +HRDL NV LD + VK+GDFGLA+ + + +
Sbjct 117 MTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARILNHDTSFAKT- 175
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
++ +PE + + SD+WS G LYEL +
Sbjct 176 --FVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTA--------------- 218
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ L + G+ P + E+ ++ + RP+ E ++
Sbjct 219 FSQKELAGKIREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILE 267
Score = 148 bits (374), Expect = 8e-37, Method: Composition-based stats.
Identities = 52/294 (18%), Positives = 97/294 (33%), Gaps = 52/294 (18%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
++ L +G G+ + R + +G K LD
Sbjct 6 EDYEVLYTIGTGSYGRCQKIRRKSDGKILVW------------------------KELDY 41
Query 647 SHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEHGPLDVWLRR- 701
A +L+ ++ H ++ + + +V EY E G L + +
Sbjct 42 GSMTEAEKQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKG 101
Query 702 --ERGHVPMAWKMVVAQQLASALSYLENKN-----LVHGNVCGRNILLARLGLAEGTSPF 754
ER ++ + + V QL AL ++ ++H ++ N+ L
Sbjct 102 TKERQYLDEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQ-------N 154
Query 755 IKLSDPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
+KL D G+ + V +++PE S + D W G L E+C
Sbjct 155 VKLGDFGLARILNHDTSFAKTFVGTPYYMSPE--QMNRMSYNEKSDIWSLGCLLYELCAL 212
Query 811 GEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862
P + S E + R+P +L + ++ L + RPS I
Sbjct 213 -MPPFTAFSQKELAGKIREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEI 265
>sp|Q4P5N0|STE20_USTMA Serine/threonine-protein kinase SMU1 OS=Ustilago
maydis (strain 521 / FGSC 9021) OX=237631 GN=SMU1
PE=3 SV=1
Length=746
Score = 218 bits (556), Expect = 3e-58, Method: Composition-based stats.
Identities = 59/262 (23%), Positives = 108/262 (41%), Gaps = 23/262 (9%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
+ +G+G G V + GT VA+K + + P+ + EI +++ H +I+
Sbjct 476 QKIGQGASGGV----FTAYQVGTNVSVAIKQMNLEQQPK-KDLIINEILVMKESRHRNIV 530
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ +G+ L +VMEY+ GSL D + + + Q+ ++++ EG+ +LH I
Sbjct 531 NFIDSFLFKGD--LWVVMEYMEGGSLTDVVTCNIMTEGQIAAVSREVLEGLRHLHQHGVI 588
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ + NVLL +K+ DFG + E R +W APE + ++
Sbjct 589 HRDIKSDNVLLSLQGDIKLTDFGFCAQIGESQA---KRTTMVGTPYWMAPEVVTRKEYGP 645
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
D+WS G+ E++ PP + T ++ P+
Sbjct 646 KVDIWSLGIMCIEMV-----EGEPPYLNENPLRALYLIATNGT--------PKINNPENL 692
Query 1141 PCEVYHLMKNCWETEASFRPTF 1162
+ + +A RP
Sbjct 693 SNTFKDFLTTSLDVDAERRPDA 714
Score = 175 bits (443), Expect = 7e-44, Method: Composition-based stats.
Identities = 56/314 (18%), Positives = 100/314 (32%), Gaps = 48/314 (15%)
Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
+P+ ET I + S L + K L +GQG V+
Sbjct 439 VPRRRETKKSTI----KDSEVIAKLQAICTDADPTKLYRSLQKIGQGASGGVF------- 487
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671
G + V +K ++ +M + H ++
Sbjct 488 -----------------TAYQVGTNVSVAIKQMNLEQQPKKDLIINEILVMKESRHRNIV 530
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
+ + +V EY+E G L + + V++++ L +L ++
Sbjct 531 NFIDSFLFKGDLWVVMEYMEGGSLTDVVTCN--IMTEGQIAAVSREVLEGLRHLHQHGVI 588
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREERVERIPWLAPECLPGG 787
H ++ N+LL+ G IKL+D G G R V W+APE +
Sbjct 589 HRDIKSDNVLLSLQGD-------IKLTDFGFCAQIGESQAKRTTMVGTPYWMAPEVVT-- 639
Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL----PEPSCPQLAT 843
+D W G +E+ +GE P + +P + PE
Sbjct 640 RKEYGPKVDIWSLGIMCIEMV-EGEPPYLNENPLRALYLIATNGTPKINNPENLSNTFKD 698
Query 844 LTSQCLTYEPTQRP 857
+ L + +RP
Sbjct 699 FLTTSLDVDAERRP 712
>sp|Q9Y572|RIPK3_HUMAN Receptor-interacting serine/threonine-protein
kinase 3 OS=Homo sapiens OX=9606 GN=RIPK3 PE=1 SV=2
Length=518
Score = 213 bits (542), Expect = 3e-58, Method: Composition-based stats.
Identities = 75/292 (26%), Positives = 124/292 (42%), Gaps = 26/292 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G+G FG V + + G VAVK + + +E+ + +L +E +++
Sbjct 27 VGKGGFGTV----FRAQHRKWGYDVAVKIVNS-------KAISREVKAMASLDNEFVLRL 75
Query 963 KGCCED---QGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018
+G E + LV +++ GSL L L +++ GM YLH Q+
Sbjct 76 EGVIEKVNWDQDPKPALVTKFMENGSLSGLLQSQCPRPWPLLCRLLKEVVLGMFYLHDQN 135
Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL--K 1074
+HRDL NVLLD + VK+ DFGL+ E G + + APE
Sbjct 136 PVLLHRDLKPSNVLLDPELHVKLADFGLSTFQGGSQSGTGSGEPG-GTLGYLAPELFVNV 194
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
K ASDV+SFG+ ++ +L + PT+ + + L EL + G
Sbjct 195 NRKASTASDVYSFGILMWAVLAGREV--ELPTEPSLVYEAVCNRQNRPSLAELPQAGPET 252
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186
P + + LM+ CW +E RP+F+ +P V + + + S
Sbjct 253 PGLEG----LKELMQLCWSSEPKDRPSFQECLPKTDEVFQMVENNMNAAVST 300
Score = 179 bits (453), Expect = 2e-46, Method: Composition-based stats.
Identities = 67/367 (18%), Positives = 123/367 (34%), Gaps = 66/367 (18%)
Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623
M + P +S ++ +E+ G+G V+ + R G
Sbjct 1 MSCVKLWPSGAPAPLVSIEELENQELV-----GKGGFGTVFRAQHRKWGYD--------- 46
Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR---- 679
V +K+++ A M+ + + + + GV +
Sbjct 47 ---------------VAVKIVNS------KAISREVKAMASLDNEFVLRLEGVIEKVNWD 85
Query 680 -GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVC 736
P+ +VT+++E+G L L+ + P + +++ + YL ++N L+H ++
Sbjct 86 QDPKPALVTKFMENGSLSGLLQSQCPR-PWPLLCRLLKEVVLGMFYLHDQNPVLLHRDLK 144
Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANS 790
N+LL +KL+D G+ E + +LAPE
Sbjct 145 PSNVLLD-------PELHVKLADFGLSTFQGGSQSGTGSGEPGGTLGYLAPELFVNVNRK 197
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ---------- 840
STA D + FG + + E L + E RQ+R PQ
Sbjct 198 ASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAVCNRQNRPSLAELPQAGPETPGLEG 257
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
L L C + EP RPSF+ L + ++ + I
Sbjct 258 LKELMQLCWSSEPKDRPSFQECLPKTDEVFQMVENNMNAAVSTVKDFLSQLRSSNRRFSI 317
Query 901 RDLGEGH 907
+ G+G
Sbjct 318 PESGQGG 324
>sp|Q84UI5|MPK1_ORYSJ Mitogen-activated protein kinase 1 OS=Oryza
sativa subsp. japonica OX=39947 GN=MPK1 PE=1 SV=1
Length=398
Score = 209 bits (533), Expect = 3e-58, Method: Composition-based stats.
Identities = 71/308 (23%), Positives = 113/308 (37%), Gaps = 29/308 (9%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KA 934
+ + +Y I +G+G +G V N TGE VA+K + A
Sbjct 46 HGGRFIQYNIFGNVFEVTAKYKPPILPIGKGAYGIVC----SALNSETGEQVAIKKIANA 101
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGSLRDYLP 991
+EI +LR + HE+I+ + + + + E + L +
Sbjct 102 FDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPPQRNSFNDVYIAYELMD-TDLHQIIR 160
Query 992 -RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
++ F QI G+ Y+H+ + +HRDL N+LL+ + +KI DFGLA+ E
Sbjct 161 SNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSE 220
Query 1051 GHEYYRVREDGDSPVFWYAPE-CLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-----SP 1104
+ ++ APE L ++ A DVWS G EL+
Sbjct 221 TD----FMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 276
Query 1105 PTKFLELIGIAQG------QMTVLRLTELLERGERLPRPDKCP---CEVYHLMKNCWETE 1155
+ELIG R L R R P+K P L++ +
Sbjct 277 LRLLMELIGTPNEADLDFVNENARRYIRQLPRHARQSFPEKFPHVHPLAIDLVEKMLTFD 336
Query 1156 ASFRPTFE 1163
R T E
Sbjct 337 PRQRITVE 344
Score = 130 bits (327), Expect = 5e-31, Method: Composition-based stats.
Identities = 34/219 (16%), Positives = 77/219 (35%), Gaps = 22/219 (10%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF--YE 657
NV+E + + P + + +V +K + + + A
Sbjct 56 FGNVFEVTAKYKPPILPIGK--GAYGIVCSALNSETGEQVAIKKIANAFDNKIDAKRTLR 113
Query 658 TASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
L+ + H ++ + + + + E ++ L +R + +
Sbjct 114 EIKLLRHMDHENIVAIRDIIPPPQRNSFNDVYIAYELMD-TDLHQIIRSNQA-LSEEHCQ 171
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+ L Y+ + N++H ++ N+LL + +K+ D G+ +
Sbjct 172 YFLYQILRGLKYIHSANVLHRDLKPSNLLLN-------ANCDLKICDFGLARTTSETDFM 224
Query 771 -ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
E V + APE L ++ + A+D W G +E+
Sbjct 225 TEYVVTRWYRAPELLLN-SSEYTAAIDVWSVGCIFMELM 262
>sp|Q5REX1|SIK2_PONAB Serine/threonine-protein kinase SIK2 OS=Pongo
abelii OX=9601 GN=SIK2 PE=2 SV=1
Length=925
Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats.
Identities = 72/291 (25%), Positives = 111/291 (38%), Gaps = 29/291 (10%)
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADC 936
+ + + LG+G+F V L + T VA+K + K+
Sbjct 1 MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLG----RHRITKTEVAIKIIDKSQL 56
Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SI 995
+ +E+ I++ L H HIIK E + L LV EY G + DYL H +
Sbjct 57 DAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKS--MLYLVTEYAKNGEIFDYLANHGRL 114
Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055
++ QI + Y H + +HRDL A N+LLDN+ +KI DF G
Sbjct 115 NESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFSFGNFFKSGELLA 174
Query 1056 RVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
R + APE + ++ D+WS GV LY L+ P
Sbjct 175 TWR----GSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGP---------- 220
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
T+ L + + G R P + HL++ + S R T +
Sbjct 221 -----TLPILRQRVLEG-RFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQI 265
Score = 191 bits (485), Expect = 2e-48, Method: Composition-based stats.
Identities = 63/323 (20%), Positives = 109/323 (34%), Gaps = 43/323 (13%)
Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
PR L + RV +I LG+G V GR R+
Sbjct 7 PRHLQRGPV---RVGFYDIE--GTLGKGNFAVVKLGRHRI-------------------- 41
Query 631 RDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688
+ V +K++D S D Y +M + H H+ ++ V +VTE
Sbjct 42 ----TKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTE 97
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
Y ++G + +L G + + Q+ SA+ Y + +VH ++ N+LL
Sbjct 98 YAKNGEIFDYLANH-GRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDN---- 152
Query 749 EGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ IK++D G S E P+ APE G +D W G L
Sbjct 153 ---NMNIKIADFSFGNFFKSGELLATWRGSPPYAAPEVFEGQQYE-GPQLDIWSMGVVLY 208
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
+ P ++ + + R+P L + L +P++R + I
Sbjct 209 VLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEH 268
Query 866 LTRLQPHNLADVLTVNPDSPASD 888
L + + +
Sbjct 269 KWMLIEVPVQRPVLYPQEQENEP 291
>sp|Q55GC2|DST2_DICDI Serine/threonine-protein kinase dst2 OS=Dictyostelium
discoideum OX=44689 GN=dst2 PE=3 SV=1
Length=1142
Score = 223 bits (568), Expect = 4e-58, Method: Composition-based stats.
Identities = 68/272 (25%), Positives = 113/272 (42%), Gaps = 30/272 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
++ EG FG V Y + TG ++AVK + D EIDIL H +I+K
Sbjct 25 EIAEGSFGTV----YKGKHLPTGNIMAVKIIALDEDETF-EDLVVEIDILNRCNHNNIVK 79
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLLFAQQICEGMAYLHAQHY 1019
Y G E L + ME GS+ + +I +Q+ ++ +G+ YLH +
Sbjct 80 YYGSWVKGDE--LFIAMECCGGGSITEIYQELNIPLNESQIAYVCRETLKGLEYLHHTNV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY--- 1076
IHRDL N+LL VK+ DFG++ + + + R +W APE ++
Sbjct 138 IHRDLKGANILLTESGDVKLADFGVSGLLDKSSK----RNTFIGTPYWMAPEVIENRSNP 193
Query 1077 -KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ +D+WS G+TL EL + S L I +L
Sbjct 194 VPYDTKADIWSLGITLIELA-EAEPPLSEIHPMKVLFQIPY------------RDPPKLK 240
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + + +++C + + + R T L+
Sbjct 241 NQENYSKDFINFIQSCLQKDPNQRKTATELLK 272
Score = 201 bits (510), Expect = 4e-51, Method: Composition-based stats.
Identities = 55/301 (18%), Positives = 106/301 (35%), Gaps = 41/301 (14%)
Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635
L + + + +G+ VY+G+ G+
Sbjct 7 LEPFVGKEDPVELFELIEEIAEGSFGTVYKGKHLPTGN---------------------- 44
Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695
+ +K++ + ++++ +H ++ +G V+G E + E G +
Sbjct 45 --IMAVKIIALDEDETFEDLVVEIDILNRCNHNNIVKYYGSWVKGDELFIAMECCGGGSI 102
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+ + + V ++ L YL + N++H ++ G NILL G +
Sbjct 103 TEIYQELNIPLNESQIAYVCRETLKGLEYLHHTNVIHRDLKGANILLTESGD-------V 155
Query 756 KLSDPGVG---LGALSREERVERIPWLAPECLPGGAN--SLSTAMDKWGFGATLLEICFD 810
KL+D GV + R + W+APE + +N T D W G TL+E+ +
Sbjct 156 KLADFGVSGLLDKSSKRNTFIGTPYWMAPEVIENRSNPVPYDTKADIWSLGITLIELA-E 214
Query 811 GEAPLQSRSPSEKEHFYQRQH----RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
E PL P + + + E CL +P QR + +L+
Sbjct 215 AEPPLSEIHPMKVLFQIPYRDPPKLKNQENYSKDFINFIQSCLQKDPNQRKTATELLKHP 274
Query 867 T 867
Sbjct 275 F 275
>sp|P31751|AKT2_HUMAN RAC-beta serine/threonine-protein kinase
OS=Homo sapiens OX=9606 GN=AKT2 PE=1 SV=2
Length=481
Score = 212 bits (539), Expect = 4e-58, Method: Composition-based stats.
Identities = 77/390 (20%), Positives = 128/390 (33%), Gaps = 61/390 (16%)
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQC--LTYEPTQRPSFRTILRDLTRL 869
EAP Q+ P +F + +L + P+ T +C T + + +
Sbjct 43 EAPDQTLPP--LNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWM 100
Query 870 QPHNLADVLTVNPDSPASDPTVFH------------------------KRYLKKIRDLGE 905
+ + ++ LG+
Sbjct 101 RAIQMVANSLKQRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGK 160
Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYK 963
G FGKV L TG A+K L+ + + E +L+ H + K
Sbjct 161 GTFGKVILV----REKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALK 216
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHR 1022
Q L VMEY G L +L R + + +I + YLH++ ++R
Sbjct 217 YAF--QTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYR 274
Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082
D+ N++LD D +KI DFGL K EG + + APE L++ + A
Sbjct 275 DIKLENLMLDKDGHIKITDFGLCK---EGISDGATMKTFCGTPEYLAPEVLEDNDYGRAV 331
Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
D W GV +YE++ Q +L R PR
Sbjct 332 DWWGLGVVMYEMMCGRLPF--------------YNQDHERLFELILMEEIRFPR--TLSP 375
Query 1143 EVYHLMKNCWETEASFR----PT-FENLIP 1167
E L+ + + R P+ + ++
Sbjct 376 EAKSLLAGLLKKDPKQRLGGGPSDAKEVME 405
Score = 167 bits (422), Expect = 1e-42, Method: Composition-based stats.
Identities = 62/308 (20%), Positives = 110/308 (36%), Gaps = 46/308 (15%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
P ++S M A + R +V + L LG+GT V +R + +
Sbjct 126 SPSDSSTTEEMEVAVSKAR---------AKVTMNDFDYLKLLGKGTFGKVI--LVREKAT 174
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
G K+ ++ ++ + + + ++ H L +
Sbjct 175 GRYYAMKILRKEVIIAKDEVAHTVT-------------------ESRVLQNTRHPFLTAL 215
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHG 733
V EY G L L RER ++ SAL YL ++++V+
Sbjct 216 KYAFQTHDRLCFVMEYANGGELFFHLSRER-VFTEERARFYGAEIVSALEYLHSRDVVYR 274
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGAN 789
++ N++L + G IK++D G+ +S + +LAPE L N
Sbjct 275 DIKLENLMLDKDG-------HIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLED--N 325
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQC 848
A+D WG G + E+ G P ++ + R P P+ +L +
Sbjct 326 DYGRAVDWWGLGVVMYEMMC-GRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGL 384
Query 849 LTYEPTQR 856
L +P QR
Sbjct 385 LKKDPKQR 392
>sp|Q9M9E9|SRK2C_ARATH Serine/threonine-protein kinase SRK2C OS=Arabidopsis
thaliana OX=3702 GN=SRK2C PE=1 SV=1
Length=343
Score = 207 bits (528), Expect = 4e-58, Method: Composition-based stats.
Identities = 82/296 (28%), Positives = 125/296 (42%), Gaps = 34/296 (11%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+ ++D+G G+FG L + + E+ AVK + + G + ++EI R+
Sbjct 1 MERYEIVKDIGSGNFGVAKLV----RDKFSKELFAVKFI--ERGQKIDEHVQREIMNHRS 54
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012
L H +II++K L LVMEY G L + + F QQ+ G+
Sbjct 55 LIHPNIIRFKEVLLTATH--LALVMEYAAGGELFGRICSAGRFSEDEARFFFQQLISGVN 112
Query 1013 YLHAQHYIHRDLAARNVLLD--NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
Y H+ HRDL N LLD VKI DFG +K G + + + +P + AP
Sbjct 113 YCHSLQICHRDLKLENTLLDGSEAPRVKICDFGYSK---SGVLHSQPKTTVGTPA-YIAP 168
Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSP--PTKFLELIGIAQGQMTVLRLTEL 1127
E L ++ +DVWS GVTLY +L + P P F + IG +
Sbjct 169 EVLSTKEYDGKIADVWSCGVTLYVMLVGAYPFEDPSDPKDFRKTIG------------RI 216
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP---ILKTV-HEKYQGQ 1179
L+ +P + E HL+ + R T E + LK + E Y+G
Sbjct 217 LKAQYAIPDYVRVSDECRHLLSRIFVANPEKRITIEEIKNHSWFLKNLPVEMYEGS 272
Score = 145 bits (365), Expect = 1e-36, Method: Composition-based stats.
Identities = 47/275 (17%), Positives = 85/275 (31%), Gaps = 17/275 (6%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
RD+ + +K ++ I + H ++ V + +V EY
Sbjct 22 RDKFSKELFAVKFIERG-QKIDEHVQREIMNHRSLIHPNIIRFKEVLLTATHLALVMEYA 80
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L + G QQL S ++Y + + H ++ N LL
Sbjct 81 AGGELFGRI-CSAGRFSEDEARFFFQQLISGVNYCHSLQICHRDLKLENTLLD-----GS 134
Query 751 TSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+P +K+ D G + + V ++APE L D W G TL +
Sbjct 135 EAPRVKICDFGYSKSGVLHSQPKTTVGTPAYIAPEVLSTKEYD-GKIADVWSCGVTLYVM 193
Query 808 CFDGEAPLQSRSPSEKEH----FYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRT 861
P + + Q+ +P+ + L S+ P +R +
Sbjct 194 LVGAYPFEDPSDPKDFRKTIGRILKAQYAIPDYVRVSDECRHLLSRIFVANPEKRITIEE 253
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896
I L+ + + S TV +
Sbjct 254 IKNHSWFLKNLPVEMYEGSLMMNGPSTQTVEEIVW 288
>sp|Q9LT35|NEK6_ARATH Serine/threonine-protein kinase Nek6 OS=Arabidopsis
thaliana OX=3702 GN=NEK6 PE=3 SV=1
Length=416
Score = 210 bits (534), Expect = 4e-58, Method: Composition-based stats.
Identities = 62/285 (22%), Positives = 112/285 (39%), Gaps = 31/285 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG L + VK ++ A + + QE+ ++ L +I++
Sbjct 10 IGRGAFGSAFLVIHKSERR----KYVVKKIRLAKQTERCKLAAIQEMSLISKLKSPYIVE 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018
YK ++ + +V Y G + + + +L + Q+ + YLH
Sbjct 66 YKDSWVEKD--CVCIVTSYCEGGDMTQMIKKSRGVFASEEKLCRWMVQLLLAIDYLHNNR 123
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRDL N+ L + V++GDFGLAK + + + + PE L + +
Sbjct 124 VLHRDLKCSNIFLTKENEVRLGDFGLAKLLGKDD----LASSMVGTPNYMCPELLADIPY 179
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
Y SD+WS G ++E+ H + ++P + L + R P P
Sbjct 180 GYKSDIWSLGCCMFEVAAHQPAFKAP---------------DMAALINKINRSSLSPLPV 224
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAP 1181
+ L+K+ RPT L+ P L+ + Q +P
Sbjct 225 MYSSSLKRLIKSMLRKNPEHRPTAAELLRHPHLQPYLAQCQNLSP 269
Score = 150 bits (378), Expect = 2e-37, Method: Composition-based stats.
Identities = 51/297 (17%), Positives = 89/297 (30%), Gaps = 36/297 (12%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ + +G+G + + LV + ++ V L
Sbjct 1 MDDYEVVEQIGRGAFGSAF----------------------LVIHKSERRKYVVKKIRLA 38
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
LA + SL+S++ ++ V +VT Y E G + +++ RG
Sbjct 39 KQTERCKLAAIQEMSLISKLKSPYIVEYKDSWVEKDCVCIVTSYCEGGDMTQMIKKSRGV 98
Query 706 V-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
QL A+ YL N ++H ++ NI L + ++L D G+
Sbjct 99 FASEEKLCRWMVQLLLAIDYLHNNRVLHRDLKCSNIFLTKENE-------VRLGDFGLAK 151
Query 765 GALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ V ++ PE L D W G + E+ A +
Sbjct 152 LLGKDDLASSMVGTPNYMCPELLADIPYGY--KSDIWSLGCCMFEVAAHQPAFKAPDMAA 209
Query 822 EKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
+ LP L L L P RP+ +LR
Sbjct 210 LINKINRSSLSPLPVMYSSSLKRLIKSMLRKNPEHRPTAAELLRHPHLQPYLAQCQN 266
>sp|Q41639|CDC2_VIGAC Cell division control protein 2 homolog
OS=Vigna aconitifolia OX=3918 GN=CDC2 PE=2 SV=1
Length=294
Score = 206 bits (523), Expect = 4e-58, Method: Composition-based stats.
Identities = 71/293 (24%), Positives = 121/293 (41%), Gaps = 29/293 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+
Sbjct 1 MEQYEKVEKIGEGTYGVV----YKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009
+ H +I++ + EK L LV EY+ L L+ ++ P Q+ +F QI
Sbjct 57 EMQHRNIVRLQDVV--HSEKRLYLVFEYLDL-DLKKHMDSSPEFVKDPRQVKMFLYQILC 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
G+AY H+ +HRDL +N+L+D +K+ DFGLA+A R +++
Sbjct 114 GIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIP---VRTFTHEVVTLWYR 170
Query 1069 APECLKEYK-FYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVL 1122
APE L + + DVWS G E++ DS K ++G +
Sbjct 171 APEILLGSRHYSTPVDVWSVGCIFAEMVNRRPLFPGDSEIDELFKIFRILGTPNEETWPG 230
Query 1123 RLTELLERGERLPRPDKCPCEV--------YHLMKNCWETEASFRPTFENLIP 1167
+ P K V +L+ + + S R T +
Sbjct 231 VTALPDFKSTFPKWPPKDLATVVPNLDAAGLNLLSSMLCLDPSKRITARIAVE 283
Score = 164 bits (414), Expect = 2e-43, Method: Composition-based stats.
Identities = 46/266 (17%), Positives = 94/266 (35%), Gaps = 39/266 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
++ ++ +G+GT VY+ RDR + LK
Sbjct 1 MEQYEKVEKIGEGTYGVVYKA------------------------RDRVTNETIALKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
L+ + SL+ ++ H ++ + V +V EY++ L +
Sbjct 37 LEQEDEGVPSTAIREISLLKEMQHRNIVRLQDVVHSEKRLYLVFEYLDL-DLKKHMDSSP 95
Query 704 GHVPMAWKMVV-AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
V ++ + Q+ ++Y + ++H ++ +N+L+ R + +KL+D G+
Sbjct 96 EFVKDPRQVKMFLYQILCGIAYCHSHRVLHRDLKPQNLLIDRR------TNSLKLADFGL 149
Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + + APE L G+ ST +D W G E+
Sbjct 150 ARAFGIPVRTFTHEVVTLWYRAPEILL-GSRHYSTPVDVWSVGCIFAEMVNRRPLFPGDS 208
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844
E ++ E + P + L
Sbjct 209 EIDELFKIFRILGTPNEETWPGVTAL 234
>sp|P22612|KAPCG_HUMAN cAMP-dependent protein kinase catalytic
subunit gamma OS=Homo sapiens OX=9606 GN=PRKACG PE=1 SV=3
Length=351
Score = 207 bits (528), Expect = 4e-58, Method: Composition-based stats.
Identities = 67/261 (26%), Positives = 108/261 (41%), Gaps = 31/261 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHI 959
LG G FG+V L + TG A+K L + E IL+ + +
Sbjct 49 TLGMGSFGRVMLV----RHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFL 104
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQH 1018
+K + +D L LVMEYVP G + L R +A Q+ + YLH+
Sbjct 105 VKLQFSFKDNS--YLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLD 162
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRDL N+L+D +++ DFG AK V R +P + APE + +
Sbjct 163 LIHRDLKPENLLIDQQGYLQVTDFGFAKRVK-----GRTWTLCGTPE-YLAPEIILSKGY 216
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
A D W+ GV +YE+ + +++ E + G R+ P
Sbjct 217 NKAVDWWALGVLIYEMAVGFPPFYAD---------------QPIQIYEKIVSG-RVRFPS 260
Query 1139 KCPCEVYHLMKNCWETEASFR 1159
K ++ HL+++ + + + R
Sbjct 261 KLSSDLKHLLRSLLQVDLTKR 281
Score = 155 bits (391), Expect = 7e-40, Method: Composition-based stats.
Identities = 52/325 (16%), Positives = 101/325 (31%), Gaps = 34/325 (10%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ + +L LG G+ V R + G + ++ V +
Sbjct 37 NTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKIL-------------NKQKVVKM 83
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
K ++ ++ + L + +V EYV G + L+R
Sbjct 84 KQVEH--------ILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQR 135
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
G A Q+ A+ YL + +L+H ++ N+L+ + G +++++D G
Sbjct 136 V-GRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQG-------YLQVTDFG 187
Query 762 VGLGALSRE-ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
R +LAPE + + + A+D W G + E+ G P + P
Sbjct 188 FAKRVKGRTWTLCGTPEYLAPEIIL--SKGYNKAVDWWALGVLIYEMAV-GFPPFYADQP 244
Query 821 SEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
+ E + R P L L L + T+R +
Sbjct 245 IQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWI 304
Query 880 VNPDSPASDPTVFHKRYLKKIRDLG 904
+ P + +
Sbjct 305 AIYEKKVEAPFIPKYTGPGDASNFD 329
>sp|Q9C6P3|CDPKX_ARATH Calcium-dependent protein kinase 33 OS=Arabidopsis
thaliana OX=3702 GN=CPK33 PE=1 SV=1
Length=521
Score = 213 bits (542), Expect = 4e-58, Method: Composition-based stats.
Identities = 76/287 (26%), Positives = 119/287 (41%), Gaps = 30/287 (10%)
Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWK 945
P K + ++LG G FG L T TG+ A K++ K + +
Sbjct 64 KPYEDVKLFYTLSKELGRGQFGVTYLC----TEKSTGKRFACKSISKKKLVTKGDKEDMR 119
Query 946 QEIDILRTLYH-EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLF 1003
+EI I++ L +I+++KG ED EK++ LVME G L D L +
Sbjct 120 REIQIMQHLSGQPNIVEFKGAYED--EKAVNLVMELCAGGELFDRILAKGHYSERAAASV 177
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+QI + H +HRDL N LL D L+K DFGL+ + EG RV +D
Sbjct 178 CRQIVNVVNICHFMGVMHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEG----RVYKD 233
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
++ APE LK ++ D+WS G+ LY LL+ + K + I +G++
Sbjct 234 IVGSAYYVAPEVLK-RRYGKEIDIWSAGIILYILLSGVPPFWAETEKGI-FDAILEGEID 291
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
E P P L++ + R + ++
Sbjct 292 F----------ESQPWP-SISNSAKDLVRRMLTQDPKRRISAAEVLK 327
Score = 134 bits (336), Expect = 2e-31, Method: Composition-based stats.
Identities = 48/287 (17%), Positives = 87/287 (30%), Gaps = 39/287 (14%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
T LG+G Y + +G K + LV D+
Sbjct 74 TLSKELGRGQFGVTY--LCTEKSTGKRFACKSISKKKLVTKGDK---------------- 115
Query 650 DIALAFYETASLMSQVS-HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708
+M +S ++ G +V E G L + +GH
Sbjct 116 ---EDMRREIQIMQHLSGQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRILA-KGHYSE 171
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
V +Q+ + ++ ++H ++ N LL+ + IK +D G+ +
Sbjct 172 RAAASVCRQIVNVVNICHFMGVMHRDLKPENFLLSS----KDEKALIKATDFGLSVFIEE 227
Query 769 R---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
++ V ++APE L +D W G L I G P + +
Sbjct 228 GRVYKDIVGSAYYVAPEVL---KRRYGKEIDIWSAGIILY-ILLSGVPPFWAETEKGIFD 283
Query 826 FYQRQH-----RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ L + LT +P +R S +L+
Sbjct 284 AILEGEIDFESQPWPSISNSAKDLVRRMLTQDPKRRISAAEVLKHPW 330
>sp|Q9W739|CDK1_RANDY Cyclin-dependent kinase 1 OS=Rana dybowskii
OX=71582 GN=CDK1 PE=2 SV=1
Length=302
Score = 206 bits (523), Expect = 4e-58, Method: Composition-based stats.
Identities = 68/295 (23%), Positives = 124/295 (42%), Gaps = 33/295 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHII 960
+GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L H +I+
Sbjct 9 KIGEGTYGVV----YKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIV 64
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGMAYLHA 1016
+ L L+ E++ + L+ YL + + + QI +G+ + HA
Sbjct 65 CLLDVLMQ--DSRLYLIFEFLSM-DLKKYLDSIPSGQYLEAMLVKSYLYQILQGIIFCHA 121
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ +HRDL +N+L+D+ ++K+ DFGLA+A RV +++ APE L
Sbjct 122 RRVLHRDLKPQNLLIDSKGVIKLADFGLARAFGIP---VRVYTHEVVTLWYRAPEVLLGS 178
Query 1077 -KFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
++ DVWS G E+ + H DS + EL G ++ + L +
Sbjct 179 VRYSTPVDVWSIGTIFAEIASKKPLFHGDSEIDQLFRISELWGTPNNEV-WPEVESLQDY 237
Query 1131 GERLPR---------PDKCPCEVYHLMKNCWETEASFRPTFEN--LIPILKTVHE 1174
P+ E L+ + + R + L P + +
Sbjct 238 KNTFPKWKGGSLAANVKNIDKEGLDLLAKMLVYDPAKRISARKALLHPYFDDLDK 292
Score = 161 bits (408), Expect = 1e-42, Method: Composition-based stats.
Identities = 45/267 (17%), Positives = 91/267 (34%), Gaps = 41/267 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
E ++ +G+GT VY+G + G V +K
Sbjct 1 MDEYAKIEKIGEGTYGVVYKGVHKATGQ------------------------IVAMKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702
L+ + SL+ ++ H ++ + V ++ ++ E++ L +L
Sbjct 37 LENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95
Query 703 RGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
G A + Q+ + + + ++H ++ +N+L+ G+ IKL+D G
Sbjct 96 SGQYLEAMLVKSYLYQILQGIIFCHARRVLHRDLKPQNLLIDSKGV-------IKLADFG 148
Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ V + + APE L G+ ST +D W G EI
Sbjct 149 LARAFGIPVRVYTHEVVTLWYRAPEVLL-GSVRYSTPVDVWSIGTIFAEIASKKPLFHGD 207
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844
+ + P++ +L
Sbjct 208 SEIDQLFRISELWGTPNNEVWPEVESL 234
>sp|C0LGX3|HSL2_ARATH LRR receptor-like serine/threonine-protein
kinase HSL2 OS=Arabidopsis thaliana OX=3702 GN=HSL2 PE=1
SV=1
Length=993
Score = 221 bits (564), Expect = 4e-58, Method: Composition-based stats.
Identities = 76/345 (22%), Positives = 128/345 (37%), Gaps = 42/345 (12%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
+ L + L + +G G G V
Sbjct 651 LFIKTKPLFKRKPKRTNKITIFQRVGFTEEDIYPQLTEDNIIGSGGSGLVYRVKLK---- 706
Query 922 GTGEMVAVKALKADCGPQHRSG--WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979
+G+ +AVK L + G + S ++ E++ L + H +I+K CC GE+ LV E
Sbjct 707 -SGQTLAVKKLWGETGQKTESESVFRSEVETLGRVRHGNIVKLLMCC--NGEEFRFLVYE 763
Query 980 YVPLGSLRDYLPRHS-------IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNV 1029
++ GSL D L + A +G++YLH +HRD+ + N+
Sbjct 764 FMENGSLGDVLHSEKEHRAVSPLDWTTRFSIAVGAAQGLSYLHHDSVPPIVHRDVKSNNI 823
Query 1030 LLDNDRLVKIGDFGLAKAVPEGHE---YYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
LLD++ ++ DFGLAK + + APE K SDV+S
Sbjct 824 LLDHEMKPRVADFGLAKPLKREDNDGVSDVSMSCVAGSYGYIAPEYGYTSKVNEKSDVYS 883
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM-------------------TVLRLTEL 1127
FGV L EL+T + S + +++ A L++L
Sbjct 884 FGVVLLELITGKRPNDSSFGENKDIVKFAMEAALCYPSPSAEDGAMNQDSLGNYRDLSKL 943
Query 1128 LERGERL-PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171
++ +L R + +V + C + RPT ++ +LK
Sbjct 944 VDPKMKLSTREYEEIEKVLDVALLCTSSFPINRPTMRKVVELLKE 988
Score = 184 bits (467), Expect = 4e-46, Method: Composition-based stats.
Identities = 51/277 (18%), Positives = 92/277 (33%), Gaps = 56/277 (20%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
++T+ + +G G VY +L+ + +K L
Sbjct 685 QLTEDNIIGSGGSGLVYRVKLKSGQTL-------------------------AVKKLWGE 719
Query 648 HHDIALA---FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ F + +V H ++ + C +V E++E+G L L E+
Sbjct 720 TGQKTESESVFRSEVETLGRVRHGNIVKLLMCCNGEEFRFLVYEFMENGSLGDVLHSEKE 779
Query 705 H-----VPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIK 756
H + + +A A LSYL + + +VH +V NILL +
Sbjct 780 HRAVSPLDWTTRFSIAVGAAQGLSYLHHDSVPPIVHRDVKSNNILLDHEMKP-------R 832
Query 757 LSDPGVGL----------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
++D G+ +S ++APE G + ++ D + FG LLE
Sbjct 833 VADFGLAKPLKREDNDGVSDVSMSCVAGSYGYIAPEY--GYTSKVNEKSDVYSFGVVLLE 890
Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT 843
+ G+ P S K+ P
Sbjct 891 LI-TGKRPNDSSFGENKDIVKFAMEAALCYPSPSAED 926
>sp|Q75LR7|SAPK1_ORYSJ Serine/threonine-protein kinase SAPK1 OS=Oryza
sativa subsp. japonica OX=39947 GN=SAPK1 PE=1 SV=1
Length=342
Score = 207 bits (527), Expect = 4e-58, Method: Composition-based stats.
Identities = 70/276 (25%), Positives = 113/276 (41%), Gaps = 26/276 (9%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+ +RD+G G+FG L + T + AVK + + G + ++EI R+
Sbjct 1 MERYEVMRDIGSGNFGVAKLV----RDVATNHLFAVKFI--ERGLKIDEHVQREIMNHRS 54
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMA 1012
L H +II++K L +VMEY G L + + + F QQ+ G++
Sbjct 55 LKHPNIIRFKEVVLTPTH--LAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVS 112
Query 1013 YLHAQHYIHRDLAARNVLLDNDRL--VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
Y H+ HRDL N LLD +KI DFG +K + + + +P + AP
Sbjct 113 YCHSMQVCHRDLKLENTLLDGSVTPRLKICDFGYSK---SSVLHSQPKSTVGTPA-YIAP 168
Query 1071 ECLKEYKFYYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E L ++ DVWS GVTLY +L + P + +T +L
Sbjct 169 EVLSRKEYDGKVADVWSCGVTLYVMLVGAYPFEDPDD----------PRNFRKTITRILS 218
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+P + + HL+ + R T +
Sbjct 219 VQYSIPDYVRVSADCRHLLSRIFVGNPEQRITIPEI 254
Score = 150 bits (379), Expect = 2e-38, Method: Composition-based stats.
Identities = 51/348 (15%), Positives = 96/348 (28%), Gaps = 45/348 (13%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ + +G G RD +K ++
Sbjct 1 MERYEVMRDIGSGNFG------------------------VAKLVRDVATNHLFAVKFIE 36
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
I + H ++ V + +V EY G L + G
Sbjct 37 RG-LKIDEHVQREIMNHRSLKHPNIIRFKEVVLTPTHLAIVMEYAAGGELFERI-CNAGR 94
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
QQL S +SY + + H ++ N LL +P +K+ D G
Sbjct 95 FSEDEARFFFQQLISGVSYCHSMQVCHRDLKLENTLLD-----GSVTPRLKICDFGYSKS 149
Query 766 AL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
++ + V ++APE L D W G TL + G P + P +
Sbjct 150 SVLHSQPKSTVGTPAYIAPEVLSRKEYD-GKVADVWSCGVTLYVMLV-GAYPFED--PDD 205
Query 823 KEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880
+F + R+ + S P +++ C + ++ H
Sbjct 206 PRNFRKTITRILSVQYSIPDYVRVSADCRHLLSRIFVGNPEQRITIPEIKNHPWFLKNLP 265
Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
+ ++ + L +V + G +A
Sbjct 266 IEMTDEYQRSMQLADMNTPSQSLE-----EVMAIIQEARKPGDAMKLA 308
>sp|Q7XKA8|SAPK5_ORYSJ Serine/threonine-protein kinase SAPK5 OS=Oryza
sativa subsp. japonica OX=39947 GN=SAPK5 PE=2 SV=1
Length=370
Score = 208 bits (529), Expect = 5e-58, Method: Composition-based stats.
Identities = 75/298 (25%), Positives = 124/298 (42%), Gaps = 29/298 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+ +R++G G+FG L N T E+VA+K + + G + +EI R+
Sbjct 1 MEKYEPVREIGAGNFGVAKLM----RNKETRELVAMKFI--ERGNRIDENVFREIVNHRS 54
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMA 1012
L H +II++K + L +VMEY G L + + + F QQ+ G++
Sbjct 55 LRHPNIIRFKEVVVTG--RHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGVS 112
Query 1013 YLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
Y HA HRDL N LLD +KI DFG +K + R + +P + AP
Sbjct 113 YCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSK---SSLLHSRPKSTVGTPA-YIAP 168
Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E L ++ +DVWS GVTLY +L + P I++ ++ E +
Sbjct 169 EVLSRREYDGKLADVWSCGVTLYVMLVGAYPFEDPKDPKNFRKTISRIMSVQYKIPEYV- 227
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP---ILKTVHEKYQGQAPSVF 1184
HL+ + R + + LK + + + +A +V+
Sbjct 228 ---------HVSQPCRHLLSRIFVANPYKRISMGEIKSHPWFLKNLPRELKEEAQAVY 276
Score = 153 bits (386), Expect = 4e-39, Method: Composition-based stats.
Identities = 52/295 (18%), Positives = 86/295 (29%), Gaps = 41/295 (14%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ + +G G R++ V +K ++
Sbjct 1 MEKYEPVREIGAGNFG------------------------VAKLMRNKETRELVAMKFIE 36
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
+ F + H ++ V V G +V EY G L + E G
Sbjct 37 RGNRIDENVF-REIVNHRSLRHPNIIRFKEVVVTGRHLAIVMEYAAGGELFERI-CEAGR 94
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
QQL +SY + H ++ N LL +P +K+ D G
Sbjct 95 FHEDEARYFFQQLVCGVSYCHAMQICHRDLKLENTLLD-----GSPAPRLKICDFGYSKS 149
Query 766 ALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+L + V ++APE L D W G TL + + P
Sbjct 150 SLLHSRPKSTVGTPAYIAPEVLSRREYD-GKLADVWSCGVTLYVMLVGAYPFEDPKDPKN 208
Query 823 ----KEHFYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
Q+++PE L S+ P +R S I L+
Sbjct 209 FRKTISRIMSVQYKIPEYVHVSQPCRHLLSRIFVANPYKRISMGEIKSHPWFLKN 263
>sp|Q8MYF1|Y2070_DICDI Probable serine/threonine-protein kinase
DDB_G0277449 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0277449
PE=3 SV=1
Length=456
Score = 211 bits (537), Expect = 5e-58, Method: Composition-based stats.
Identities = 58/267 (22%), Positives = 103/267 (39%), Gaps = 28/267 (10%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRT 953
+G+G FGKV + + T ++ A+K +K + + E DIL+
Sbjct 127 NFIIKHLVGKGGFGKV----FQVVHVDTQKVYALKVIKKNHIIAKKSVVNTLAEKDILKK 182
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMA 1012
+ H I+ Q EK L LVM++V G L +L + + Q+ + ++ +
Sbjct 183 ISHPFIVNLHYAF--QNEKKLYLVMDFVNGGQLFYHLQKEAIFSEDQVRFYMAELILALE 240
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+LH + +HRDL N+LLD+ + DFGLAK + + + APE
Sbjct 241 HLHDSNIVHRDLKPENILLDSQGHCILTDFGLAKL---EVKTNNETFSFAGTLEYMAPEM 297
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
++ A D WS G+ +Y+++ + L + E
Sbjct 298 IQHATCGKAVDWWSIGILMYDMMIGKPPFEH----------------KNRALMQEKIISE 341
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFR 1159
+ P L+ + + R
Sbjct 342 KAKFPKFVSSSARSLINGLLTKDPTKR 368
Score = 169 bits (427), Expect = 1e-43, Method: Composition-based stats.
Identities = 46/282 (16%), Positives = 95/282 (34%), Gaps = 41/282 (15%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ ++ +G+G V++ + L
Sbjct 121 NSINLSNFIIKHLVGKGGFGKVFQVV------------------------HVDTQKVYAL 156
Query 642 KVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
KV+ +H + ++ ++SH + +H + +V ++V G L
Sbjct 157 KVIKKNHIIAKKSVVNTLAEKDILKKISHPFIVNLHYAFQNEKKLYLVMDFVNGGQLFYH 216
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
L++E +L AL +L + N+VH ++ NILL G L+
Sbjct 217 LQKE-AIFSEDQVRFYMAELILALEHLHDSNIVHRDLKPENILLDSQGHCI-------LT 268
Query 759 DPGVGLGALSREERV----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
D G+ + + ++APE + + A+D W G + ++
Sbjct 269 DFGLAKLEVKTNNETFSFAGTLEYMAPEMIQHA--TCGKAVDWWSIGILMYDMMIGKPPF 326
Query 815 LQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
+E + + P+ +L + LT +PT+R
Sbjct 327 EHKNRALMQEKIISEKAKFPKFVSSSARSLINGLLTKDPTKR 368
>sp|Q38HL5|HOG1_ASPGL Mitogen-activated protein kinase hog1 OS=Aspergillus
glaucus OX=41413 GN=hog1 PE=3 SV=1
Length=366
Score = 208 bits (529), Expect = 5e-58, Method: Composition-based stats.
Identities = 68/283 (24%), Positives = 107/283 (38%), Gaps = 29/283 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + TG VAVK + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVCA----ARDQLTGAPVAVKKIMKPFSTPVLSKRTYRELKLLKHLGHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L L + + F QI G+ Y+H+
Sbjct 80 ICLSDIFISPLED-IYSVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI FGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILINENCDLKICGFGLARVQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126
D+WS G E+L + + EL+G + LR +
Sbjct 192 DVEVDIWSAGCIFAEMLDGKPLFPGKDHVNQFSIITELLGTPPDDVIETICSENTLRFVK 251
Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
L + ER P R E L++ + R +
Sbjct 252 SLPKRERQPLTSRFKNADPEAVDLLERMLVFDPKKRIRAGEAL 294
Score = 124 bits (312), Expect = 2e-29, Method: Composition-based stats.
Identities = 35/231 (15%), Positives = 74/231 (32%), Gaps = 19/231 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E + + M + RD+ V +K ++ P ++ Y
Sbjct 10 FGTTFE---ITSRYTELQPVGMGAFGLVCAARDQLTGAPVAVKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L L + +
Sbjct 67 ELKLLKHLGHENIICLSDIFISPLEDIYSVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ G+ V
Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICGFGLARVQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ APE + +D W G E+ DG+ + +
Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-DGKPLFPGKDHVNQFSI 225
>sp|P34102|PK3_DICDI Protein kinase 3 OS=Dictyostelium discoideum
OX=44689 GN=pkgC PE=3 SV=2
Length=910
Score = 220 bits (561), Expect = 5e-58, Method: Composition-based stats.
Identities = 63/267 (24%), Positives = 110/267 (41%), Gaps = 33/267 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960
LG G FG+V L TG+ A+K L + + E +L T+ H I+
Sbjct 504 LGVGSFGRVYLV----RRKDTGKFYAMKVLNKKDMLKKKQIAHTNTEKMVLSTMDHPFIV 559
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ Q E L + M+YVP G L +L + + ++ + YLH+ +
Sbjct 560 RLHFAF--QNEDFLFMCMDYVPGGELFHHLQKAGKFPEELAKFYIAEVICSLHYLHSNNI 617
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKA-------VPEGHEYYRVREDGDSPVFWYAPEC 1072
I+RD+ N+LLD + +K+ DFGL+K+ G E +P + APE
Sbjct 618 IYRDIKPENILLDEEGHIKLTDFGLSKSGITSVVGSKNGGEGGFATTFCGTPE-YLAPEI 676
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ A+D WS G+ L+E+LT +A + + + +++
Sbjct 677 ITGAGHGKAADWWSVGILLFEMLTGRSPF------------LASNRNDMYK--SMIQGNL 722
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFR 1159
R+ P + L++ + + R
Sbjct 723 RM--PMFLSSDAQDLLEKLLVPDPNKR 747
Score = 174 bits (440), Expect = 5e-43, Method: Composition-based stats.
Identities = 57/296 (19%), Positives = 96/296 (32%), Gaps = 50/296 (17%)
Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636
++ S ++ + L LG G+ VY R + G
Sbjct 486 NKQSIKKLTIDDFELLKVLGVGSFGRVYLVRRKDTGKFY--------------------- 524
Query 637 LRVVLKVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+KVL+ ++S + H + +H M +YV G
Sbjct 525 ---AMKVLNKKDMLKKKQIAHTNTEKMVLSTMDHPFIVRLHFAFQNEDFLFMCMDYVPGG 581
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L L++ G P ++ +L YL + N+++ ++ NILL G
Sbjct 582 ELFHHLQKA-GKFPEELAKFYIAEVICSLHYLHSNNIIYRDIKPENILLDEEG------- 633
Query 754 FIKLSDPGVGLGALSR-------------EERVERIPWLAPECLPGGANSLSTAMDKWGF 800
IKL+D G+ ++ +LAPE + G + A D W
Sbjct 634 HIKLTDFGLSKSGITSVVGSKNGGEGGFATTFCGTPEYLAPEIITGAGH--GKAADWWSV 691
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
G L E+ L S + Q R+P L + L +P +R
Sbjct 692 GILLFEMLTGRSPFLASNRNDMYKSMIQGNLRMPMFLSSDAQDLLEKLLVPDPNKR 747
>sp|Q9UV50|HOG1_DEBHA Mitogen-activated protein kinase HOG1 OS=Debaryomyces
hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394
/ JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=HOG1 PE=1
SV=3
Length=387
Score = 208 bits (530), Expect = 5e-58, Method: Composition-based stats.
Identities = 66/293 (23%), Positives = 109/293 (37%), Gaps = 32/293 (11%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRT 953
+ +G G FG V + TG+ VAVK + K +E+ +L+
Sbjct 21 NRYTDLNPVGMGAFGLVC----SAIDKLTGQNVAVKKIMKPFSTSVLAKRTYRELKLLKH 76
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013
L HE++I E + V E L L + + F QI G+ Y
Sbjct 77 LRHENLITLDDIFLSPLED-IYFVTEL-QGTDLHRLLTSRPLEKQFIQYFTYQILRGLKY 134
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+H+ IHRDL N+L++ + +KI DFGLA+ Y S ++ APE +
Sbjct 135 VHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIM 188
Query 1074 KE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------T 1120
K+ D+WS G L E++ + EL+G +
Sbjct 189 LTWQKYDTEVDLWSVGCILSEMIEGKPLFPGKDHVHQFSIITELLGSPPPDVIETICSEN 248
Query 1121 VLRLTELLERGERLPRPD---KCP---CEVYHLMKNCWETEASFRPTFENLIP 1167
LR + L + +P + +C E L+ + R + + +
Sbjct 249 TLRFVQSLPHRDPIPFSERFAQCSHVEPEAIDLLAKMLIFDPKKRISALDALS 301
Score = 139 bits (349), Expect = 4e-34, Method: Composition-based stats.
Identities = 49/319 (15%), Positives = 91/319 (29%), Gaps = 38/319 (12%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
V+E R G + D+ V +K ++ P +A Y
Sbjct 13 FGTVFEITNRYTDLNPVGMGAF---GLVCSAIDKLTGQNVAVKKIMKPFSTSVLAKRTYR 69
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H +L + + + + VTE + L L + +
Sbjct 70 ELKLLKHLRHENLITLDDIFLSPLEDIYFVTEL-QGTDLHRLLTSR--PLEKQFIQYFTY 126
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + ++H ++ NIL+ + +K+ D G+ V
Sbjct 127 QILRGLKYVHSAGVIHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 179
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--------------------FDGEAPL 815
+ APE + T +D W G L E+ G P
Sbjct 180 RYYRAPE-IMLTWQKYDTEVDLWSVGCILSEMIEGKPLFPGKDHVHQFSIITELLGSPPP 238
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
E+ + LP + +QC EP +L + + L
Sbjct 239 DVIETICSENTLRFVQSLPHRDPIPFSERFAQCSHVEPEAIDLLAKMLIFDPKKRISALD 298
Query 876 DVLTVNPDSPASDPTVFHK 894
+ +
Sbjct 299 ALSHPYMEPYHDPTDEPVC 317
>sp|P24348|LET23_CAEEL Receptor tyrosine-protein kinase let-23
OS=Caenorhabditis elegans OX=6239 GN=let-23 PE=1 SV=3
Length=1323
Score = 223 bits (568), Expect = 5e-58, Method: Composition-based stats.
Identities = 83/276 (30%), Positives = 130/276 (47%), Gaps = 22/276 (8%)
Query 902 DLGEGHFGKVSLYCYDPTN-DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960
LG G FG V Y P VA+K + D +E + L H++++
Sbjct 890 KLGAGAFGTVFAGIYYPKRAKNVKIPVAIKVFQTDQS--QTDEMLEEATNMFRLRHDNLL 947
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQH 1018
K G C + L++V Y PLG+L+++L + ++G + +L+ QI GM YL Q
Sbjct 948 KIIGFCMH--DDGLKIVTIYRPLGNLQNFLKLHKENLGAREQVLYCYQIASGMQYLEKQR 1005
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRDLA RNVL+ V+I DFGL+K + + ++ G + W A E ++ +
Sbjct 1006 VVHRDLATRNVLVKKFNHVEITDFGLSKILKHDADSITIKS-GKVAIKWLAIEIFSKHCY 1064
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+ASDVW+FGVT +E++T S M+ + L+ G RL +P
Sbjct 1065 THASDVWAFGVTCWEIITFGQS--------------PYQGMSTDSIHNFLKDGNRLSQPP 1110
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
C ++Y + CW + RP FE L K +
Sbjct 1111 NCSQDLYQELLRCWMADPKSRPGFEILYERFKEFCK 1146
Score = 206 bits (525), Expect = 8e-53, Method: Composition-based stats.
Identities = 65/301 (22%), Positives = 118/301 (39%), Gaps = 37/301 (12%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
N+S++ + + LG G V+ G P R +
Sbjct 870 PNMSRICLIPSSELQTKLDKKLGAGAFGTVFAGI-------------------YYPKRAK 910
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
++ V +KV E A+ M ++ H +L + G C+ +VT Y G
Sbjct 911 NVKIPVAIKVFQTDQSQT-DEMLEEATNMFRLRHDNLLKIIGFCMHDDGLKIVTIYRPLG 969
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753
L +L+ + ++ +++ Q+AS + YLE + +VH ++ RN+L+ +
Sbjct 970 NLQNFLKLHKENLGAREQVLYCYQIASGMQYLEKQRVVHRDLATRNVLVKKFN------- 1022
Query 754 FIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
++++D G+ +++ + I WLA E + + A D W FG T EI
Sbjct 1023 HVEITDFGLSKILKHDADSITIKSGKVAIKWLAIEIFS--KHCYTHASDVWAFGVTCWEI 1080
Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865
G++P Q S +F + +RL P L +C +P RP F +
Sbjct 1081 ITFGQSPYQGMSTDSIHNFLKDGNRLSQPPNCSQDLYQELLRCWMADPKSRPGFEILYER 1140
Query 866 L 866
Sbjct 1141 F 1141
>sp|Q336X9|MPK6_ORYSJ Mitogen-activated protein kinase 6 OS=Oryza
sativa subsp. japonica OX=39947 GN=MPK6 PE=2 SV=1
Length=376
Score = 208 bits (529), Expect = 5e-58, Method: Composition-based stats.
Identities = 75/328 (23%), Positives = 126/328 (38%), Gaps = 35/328 (11%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHR 941
+ + +Y IR +G G +G V N GE VA+K + A
Sbjct 29 YNVYGNFFEVSSKYAPPIRPIGRGAYGIVCA----AVNSENGEEVAIKKIGNAFDNHIDA 84
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL---QLVMEYVPLGSLRDYLP-RHSIGL 997
+EI +LR + HE+II K + +V E + L + +
Sbjct 85 KRTLREIKLLRHMDHENIIAIKDIIRPPRRDNFNDVYIVSELMD-TDLHQIIRSNQPLTD 143
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057
F Q+ G+ Y+H+ + +HRDL N+ L+ + +KI DFGLA+ E +
Sbjct 144 DHCQYFLYQLLRGLKYVHSANVLHRDLKPSNLFLNANCDLKIADFGLARTTTETD----L 199
Query 1058 REDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-------------- 1102
+ ++ APE L ++ A DVWS G L E++T
Sbjct 200 MTEYVVTRWYRAPELLLNCSQYTAAIDVWSVGCILGEIVTRQPLFPGRDYIQQLKLITEL 259
Query 1103 --SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
SP L + + + +L + + RL R L++ + S R
Sbjct 260 IGSPDDSSLGFLRSDNARRYMKQLPQYPRQDFRL-RFRNMSAGAVDLLEKMLVFDPSRRI 318
Query 1161 TFENLI--PILKTVHEKYQGQA-PSVFS 1185
T + + P L ++H+ + P+ FS
Sbjct 319 TVDEALHHPYLASLHDINEEPTCPAPFS 346
Score = 126 bits (316), Expect = 9e-30, Method: Composition-based stats.
Identities = 43/242 (18%), Positives = 80/242 (33%), Gaps = 48/242 (20%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
F V K + +G+G V G V
Sbjct 35 FFEVSSKYAPPIRPIGRGAYGIVCAAVNSENGE------------------------EVA 70
Query 641 LKVLD---PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN------IMVTEYVE 691
+K + +H D L+ + H ++ + + +R P +V+E ++
Sbjct 71 IKKIGNAFDNHIDAKRT-LREIKLLRHMDHENIIAIKDI-IRPPRRDNFNDVYIVSELMD 128
Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751
L +R + + QL L Y+ + N++H ++ N+ L
Sbjct 129 -TDLHQIIRSNQ-PLTDDHCQYFLYQLLRGLKYVHSANVLHRDLKPSNLFLN-------A 179
Query 752 SPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ +K++D G+ + E V + APE L + + A+D W G L EI
Sbjct 180 NCDLKIADFGLARTTTETDLMTEYVVTRWYRAPELLLNC-SQYTAAIDVWSVGCILGEIV 238
Query 809 FD 810
Sbjct 239 TR 240
>sp|Q55FT4|TSUA_DICDI Probable serine/threonine-protein kinase
tsuA OS=Dictyostelium discoideum OX=44689 GN=tsuA PE=1 SV=1
Length=2247
Score = 224 bits (570), Expect = 6e-58, Method: Composition-based stats.
Identities = 70/259 (27%), Positives = 114/259 (44%), Gaps = 26/259 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+GEG FGKV Y TG++VA K + K + +QEIDIL+ L H +II+
Sbjct 11 IGEGSFGKV----YKYRKKFTGQLVACKVISKKGKNEEDILSLRQEIDILKNLSHPNIIQ 66
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ C E++ E LV EY G L + ++ + + Q+ + YLH + I
Sbjct 67 FISCFENKNE--FTLVTEYAD-GDLSQIISEEKTLSVDLIQSICYQLVIALNYLHYKKVI 123
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRD+ +N+L+ + +K+ DFG AK + + + APE ++E + Y
Sbjct 124 HRDIKPQNILITSGGQIKVCDFGFAKTISSNS---ILLTSLKGTPLYLAPEIIQEQPYDY 180
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
+D+WS G+ LY++L SPP L + LE +P+
Sbjct 181 KADLWSLGIILYQILVG-----SPPFSANSLADLVH---------MTLESNIEIPKELNK 226
Query 1141 PCEVYHLMKNCWETEASFR 1159
++ L + R
Sbjct 227 YPDLVSLFRQLLCKNPDKR 245
Score = 182 bits (461), Expect = 7e-45, Method: Composition-based stats.
Identities = 57/279 (20%), Positives = 99/279 (35%), Gaps = 45/279 (16%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
+ + +G+G+ VY+ R + V KV+
Sbjct 3 DDYKLIGQIGEGSFGKVYK------------------------YRKKFTGQLVACKVISK 38
Query 647 SHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ L+ + ++ +SH ++ E +VTEY + G L + E+
Sbjct 39 KGKNEEDILSLRQEIDILKNLSHPNIIQFISCFENKNEFTLVTEYAD-GDLSQIISEEK- 96
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + + QL AL+YL K ++H ++ +NIL+ G IK+ D G
Sbjct 97 TLSVDLIQSICYQLVIALNYLHYKKVIHRDIKPQNILITSGGQ-------IKVCDFGFAK 149
Query 765 GALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
S +LAPE + D W G L +I G P + S
Sbjct 150 TISSNSILLTSLKGTPLYLAPEIIQEQPYDY--KADLWSLGIILYQILV-GSPPFSANSL 206
Query 821 SEKEHFYQRQH-RLPE--PSCPQLATLTSQCLTYEPTQR 856
++ H + +P+ P L +L Q L P +R
Sbjct 207 ADLVHMTLESNIEIPKELNKYPDLVSLFRQLLCKNPDKR 245
>sp|Q8TD08|MK15_HUMAN Mitogen-activated protein kinase 15 OS=Homo
sapiens OX=9606 GN=MAPK15 PE=1 SV=1
Length=544
Score = 213 bits (542), Expect = 6e-58, Method: Composition-based stats.
Identities = 67/288 (23%), Positives = 115/288 (40%), Gaps = 29/288 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTL-YHEHII 960
LG+G +G V + + TGE+VA+K + A +EI +L+ H +II
Sbjct 19 LGQGAYGIV----WKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGDHPNII 74
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHY 1019
+ ++ + LV E++ L + + + + Q+ +LH+ H
Sbjct 75 SLLDVIRAENDRDIYLVFEFMD-TDLNAVIRKGGLLQDVHVRSIFYQLLRATRFLHSGHV 133
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKA---VPEGHEYYRVREDGDSPVFWYAPECLK-E 1075
+HRD NVLLD + VK+ DFGLA++ +PEG E V E + ++ APE L
Sbjct 134 VHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTE-YVATRWYRAPEVLLSS 192
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQS--------------PPTKFLELIGIAQGQMTV 1121
+++ D+WS G L E+L PP +L+ + G
Sbjct 193 HRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSGCRAS 252
Query 1122 L--RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ +L + P E L++ R + +
Sbjct 253 VLHQLGSRPRQTLDALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQ 300
Score = 136 bits (343), Expect = 3e-32, Method: Composition-based stats.
Identities = 52/271 (19%), Positives = 90/271 (33%), Gaps = 53/271 (20%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD---PSHH 649
LGQG V++ DR V +K +
Sbjct 17 RQLGQGAYGIVWKAV------------------------DRRTGEVVAIKKIFDAFRDKT 52
Query 650 DIALAFYETASLMSQV-SHTHLAFVHGVCVRGPEN--IMVTEYVEHGPLDVWLRRERGHV 706
D F +L+ + H ++ + V + +V E+++ L+ +R+ G +
Sbjct 53 DAQRTF-REITLLQEFGDHPNIISLLDVIRAENDRDIYLVFEFMD-TDLNAVIRKG-GLL 109
Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766
+ QL A +L + ++VH + N+LL + +KL D G+
Sbjct 110 QDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLD-------ANCTVKLCDFGLARSL 162
Query 767 ---------LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ E V + APE L ++ + +D W G L E+ G
Sbjct 163 GDLPEGPEDQAVTEYVATRWYRAPEVLLS-SHRYTLGVDMWSLGCILGEML-RGRPLFPG 220
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQC 848
S + +P PS L L S C
Sbjct 221 TSTLHQLELILE--TIPPPSEEDLLALGSGC 249
>sp|Q6P4S6|SIK3_MOUSE Serine/threonine-protein kinase SIK3 OS=Mus
musculus OX=10090 GN=Sik3 PE=1 SV=4
Length=1369
Score = 223 bits (568), Expect = 6e-58, Method: Composition-based stats.
Identities = 69/279 (25%), Positives = 118/279 (42%), Gaps = 29/279 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEI 948
Y + R +G+G+F V T+ T VA+K + K+ ++ +E+
Sbjct 59 MAARIGYYEIDRTIGKGNFAVVK----RATHLVTKAKVAIKIIDKSQLDEENLKKIFREV 114
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQI 1007
I++ L H HII+ E E+ + LV EY G + D+L H + + +QI
Sbjct 115 QIMKMLCHPHIIRLYQVME--TERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQI 172
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ + H ++ +HRDL A N+LLD + +KI DFG + G ++ SP +
Sbjct 173 VTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPG---QLLKTWCGSPP-Y 228
Query 1068 YAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
APE + ++ D+WS GV LY L+ T+ L
Sbjct 229 AAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFD---------------GSTLQNLRA 273
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ G + P E HL+++ + + R + E +
Sbjct 274 RVLSG-KFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQI 311
Score = 176 bits (447), Expect = 2e-43, Method: Composition-based stats.
Identities = 54/292 (18%), Positives = 95/292 (33%), Gaps = 42/292 (14%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
R+ EI +G+G V V + +V +K
Sbjct 62 RIGYYEID--RTIGKGNFAVVKRATHLV------------------------TKAKVAIK 95
Query 643 VLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
++D S + + +M + H H+ ++ V +VTEY G + L
Sbjct 96 IIDKSQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLV 155
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
G + +Q+ +A+ + +N+VH ++ N+LL + IK++D
Sbjct 156 AH-GRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLD-------ANLNIKIADF 207
Query 761 GVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
G + P+ APE G +D W G L + G P
Sbjct 208 GFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYD-GPKVDIWSLGVVLY-VLVCGALPFDG 265
Query 818 RSPSEKE-HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ + R+P + L L +P +R S I R
Sbjct 266 STLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICRHKWM 317
>sp|Q8GRU6|HAR1_LOTJA Leucine-rich repeat receptor-like kinase
protein HAR1 OS=Lotus japonicus OX=34305 GN=HAR1 PE=1 SV=1
Length=986
Score = 221 bits (563), Expect = 6e-58, Method: Composition-based stats.
Identities = 70/312 (22%), Positives = 123/312 (39%), Gaps = 23/312 (7%)
Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932
+ A + LK+ +G+G G V + G VA+K L
Sbjct 671 HRAQAWKLTAFQRLEIKAEDVVECLKEENIIGKGGAGIVYRG-----SMPNGTDVAIKRL 725
Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992
++ G++ EI+ L + H +I++ G ++ L+ EY+P GSL ++L
Sbjct 726 VGQGSGRNDYGFRAEIETLGKIRHRNIMRLLGYVSNKDTN--LLLYEYMPNGSLGEWLHG 783
Query 993 HS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
+ A + G+ Y+H IHRD+ + N+LLD D + DFGLAK
Sbjct 784 AKGGHLRWEMRYKIAVEAARGLCYMHHDCSPLIIHRDVKSNNILLDADFEAHVADFGLAK 843
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
+ + + S + APE K SDV+SFGV L EL+
Sbjct 844 FLYDPGASQSMSSIAGS-YGYIAPEYAYTLKVDEKSDVYSFGVVLLELIIGRKPVGE-FG 901
Query 1107 KFLELIGIAQGQMTVLR-------LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
++++G M+ L + +++ P ++++ C + R
Sbjct 902 DGVDIVGWVNKTMSELSQPSDTALVLAVVDPRLSG-YPLTSVIHMFNIAMMCVKEMGPAR 960
Query 1160 PTFENLIPILKT 1171
PT ++ +L
Sbjct 961 PTMREVVHMLTN 972
Score = 187 bits (475), Expect = 4e-47, Method: Composition-based stats.
Identities = 52/358 (15%), Positives = 102/358 (28%), Gaps = 51/358 (14%)
Query 562 IIMRGARASPRTLNLSQLSFHRVDQKE----ITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
++ + + L+ + ++ + + + +G+G VY G
Sbjct 664 VVRKRRLHRAQAWKLTAFQRLEIKAEDVVECLKEENIIGKGGAGIVYRG----------- 712
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676
V +K L F + ++ H ++ + G
Sbjct 713 --------------SMPNGTDVAIKRLVGQGSGRNDYGFRAEIETLGKIRHRNIMRLLGY 758
Query 677 CVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKN---LVH 732
N+++ EY+ +G L WL + GH+ + +A + A L Y+ + ++H
Sbjct 759 VSNKDTNLLLYEYMPNGSLGEWLHGAKGGHLRWEMRYKIAVEAARGLCYMHHDCSPLIIH 818
Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL------SREERVERIPWLAPECLPG 786
+V NILL ++D G+ S ++APE
Sbjct 819 RDVKSNNILLD-------ADFEAHVADFGLAKFLYDPGASQSMSSIAGSYGYIAPEYA-- 869
Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTS 846
+ D + FG LLE+ G P + + E S P L
Sbjct 870 YTLKVDEKSDVYSFGVVLLELII-GRKP-VGEFGDGVDIVGWVNKTMSELSQPSDTALVL 927
Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
+ + P I + T + +
Sbjct 928 AVVDPRLSGYPLTSVIHMFNIAMMCVKEMGPARPTMREVVHMLTNPPQSNTSTQDLIN 985
>sp|Q8INB9|AKT1_DROME RAC serine/threonine-protein kinase OS=Drosophila
melanogaster OX=7227 GN=Akt PE=1 SV=3
Length=611
Score = 214 bits (546), Expect = 6e-58, Method: Composition-based stats.
Identities = 68/260 (26%), Positives = 102/260 (39%), Gaps = 28/260 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTLYHEHII 960
LG+G FGKV L T ++ A+K LK + Q E +L++ H +I
Sbjct 272 LGKGTFGKVILC----REKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHPFLI 327
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHY 1019
K Q L VM+YV G L +L I + + +I + YLH+Q
Sbjct 328 SLKYSF--QTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGI 385
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
I+RDL N+LLD D +K+ DFGL K E Y R + + APE L + +
Sbjct 386 IYRDLKLENLLLDKDGHIKVADFGLCK---EDITYGRTTKTFCGTPEYLAPEVLDDNDYG 442
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
A D W GV +YE++ + L + + + P
Sbjct 443 QAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVK----------------FPRN 486
Query 1140 CPCEVYHLMKNCWETEASFR 1159
E +L+ + R
Sbjct 487 ITDEAKNLLAGLLAKDPKKR 506
Score = 163 bits (412), Expect = 1e-40, Method: Composition-based stats.
Identities = 71/400 (18%), Positives = 125/400 (31%), Gaps = 56/400 (14%)
Query 475 WSTSHPYRLILT-VAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAAL 533
S S P +L R + + F I V+E R+F EL
Sbjct 145 DSASTPSDFLLNNFTVRGCQIMTVDRPKPFTFIIRGLQWTTVIE---RTFAVESELERQQ 201
Query 534 QGCLLRAGDDCFSLRRCCLPQPGETSNLI------IMRGARASPRTLNL---SQLSFHRV 584
+R P E +++ I + ++ + +V
Sbjct 202 WTEAIRNVSSRLIDVGEVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKV 261
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ L LG+GT V + R++ +K+L
Sbjct 262 TLENFEFLKVLGKGTFGKV------------------------ILCREKATAKLYAIKIL 297
Query 645 DPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
D + ++ +H L + V +YV G L L
Sbjct 298 KKEVIIQKDEVAHTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSH 357
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
ER ++ SAL YL ++ +++ ++ N+LL + G IK++D G
Sbjct 358 ERI-FTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDG-------HIKVADFG 409
Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ + + +LAPE L N A+D WG G + E+ G P +
Sbjct 410 LCKEDITYGRTTKTFCGTPEYLAPEVLDD--NDYGQAVDWWGTGVVMYEMIC-GRLPFYN 466
Query 818 RSPSEKEHFY-QRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
R + + P + L + L +P +R
Sbjct 467 RDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKR 506
>sp|A1A5Q6|SMK_RAT Sperm motility kinase OS=Rattus norvegicus
OX=10116 GN=Smok PE=2 SV=1
Length=654
Score = 216 bits (549), Expect = 6e-58, Method: Composition-based stats.
Identities = 63/291 (22%), Positives = 114/291 (39%), Gaps = 31/291 (11%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
+ + + + LG+G FG+V L ++ T VA+K L
Sbjct 7 CQDLRSSPFQEDALTDHYRILASLGQGGFGEVKL----ASHLLTQTKVAIKVLPKS---N 59
Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLA 998
K EI+I+++L H HIIK + +++ +V+E+ G L + +
Sbjct 60 KNLLLKSEIEIMKSLDHPHIIKLLHIIDTN--ENIFIVLEHAVGGELLTRIEDFGYLPEE 117
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
+ +Q+ + Y H + IHRD+ N+LLD+ VK+ DFGL+ + G + +
Sbjct 118 ECNRLFRQMVLALQYCHQRGIIHRDIKPENILLDHKGNVKLSDFGLSTKIVMGQKLTTL- 176
Query 1059 EDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
+ + APE + A DVWS GV LY + T C Q + ++ ++
Sbjct 177 ---CGTLPYCAPELFNLNGYDGQAIDVWSLGVVLYYMATGCLPFQGFTYQAIKQKILSGR 233
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
RL +++ ++ RP ++
Sbjct 234 YSVNFRL----------------SPDLWDVIAKLLTVNPRERPRVHEILRF 268
Score = 183 bits (465), Expect = 4e-47, Method: Composition-based stats.
Identities = 65/382 (17%), Positives = 117/382 (31%), Gaps = 59/382 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
L+ LGQG V + +V +KVL
Sbjct 21 TDHYRILASLGQGGFGEV------------------------KLASHLLTQTKVAIKVLP 56
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
S+ ++ L +M + H H+ + + +V E+ G L + + G+
Sbjct 57 KSNKNLLLK--SEIEIMKSLDHPHIIKLLHIIDTNENIFIVLEHAVGGELLTRI-EDFGY 113
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+P + +Q+ AL Y + ++H ++ NILL G +KLSD G+
Sbjct 114 LPEEECNRLFRQMVLALQYCHQRGIIHRDIKPENILLDHKG-------NVKLSDFGLSTK 166
Query 766 ALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ +P+ APE A+D W G L + +
Sbjct 167 IVMGQKLTTLCGTLPYCAPELFNLNGYD-GQAIDVWSLGVVLYYMATGCLPFQGFTYQAI 225
Query 823 KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
K+ ++ + P L + ++ LT P +RP ILR N +V +
Sbjct 226 KQKILSGRYSVNFRLSPDLWDVIAKLLTVNPRERPRVHEILRFNW---LKNENEVSPSSL 282
Query 883 DSPASDPTVFHKRYLKKIRDLGEGH---------FGKVSLYCYDPTNDGTGEMVAVK--- 930
+ +G F +V E ++K
Sbjct 283 GGNTDSHPDPTILVMMGDMGYEQGQIRESLRERKFDQVMATYLMLREKACSEDKSIKTPH 342
Query 931 ------ALKADCGPQHRSGWKQ 946
LK+ + +
Sbjct 343 PTQCAQTLKSTGSTTEKQTTLR 364
>sp|Q8H1D6|RBK1_ARATH Receptor-like cytosolic serine/threonine-protein
kinase RBK1 OS=Arabidopsis thaliana OX=3702 GN=RBK1
PE=1 SV=1
Length=467
Score = 211 bits (536), Expect = 6e-58, Method: Composition-based stats.
Identities = 76/340 (22%), Positives = 135/340 (40%), Gaps = 33/340 (10%)
Query 842 ATLTSQCLT-YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
LT + L +P PS + + + + +
Sbjct 105 YELTRKNLRRKQPKLTPSESAFTCEAFFMAKPSWRNFTYEELAVATDYFNPENM------ 158
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTLYHEH 958
+G+G +V GE VA+K L + + + E+ I+ + H +
Sbjct 159 --IGKGGHAEVYKGVL-----INGETVAIKKLMSHAKEEEERVSDFLSELGIIAHVNHPN 211
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHA 1016
+ +G D+G L V+EY P GSL L + A I +G++YLH
Sbjct 212 AARLRGFSSDRG---LHFVLEYAPYGSLASMLFGSEECLEWKIRYKVALGIADGLSYLHN 268
Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+ IHRD+ A N+LL++D +I DFGLAK +PE ++ V + + APE
Sbjct 269 ACPRRIIHRDIKASNILLNHDYEAQISDFGLAKWLPENWPHHVV-FPIEGTFGYLAPEYF 327
Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
DV++FGV L E++T + + + ++ A+ + + ++++
Sbjct 328 MHGIVDEKIDVFAFGVLLLEIITSRRAVDTASRQ--SIVAWAKPFLEKNSMEDIVDPRLG 385
Query 1134 LPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170
P E+ +M C A+ RP L+ +L+
Sbjct 386 NMFN---PTEMQRVMLTASMCVHHIAAMRPDMTRLVQLLR 422
Score = 168 bits (426), Expect = 2e-43, Method: Composition-based stats.
Identities = 62/322 (19%), Positives = 104/322 (32%), Gaps = 64/322 (20%)
Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626
A+ S R +L+ V + +G+G VY+G L +
Sbjct 134 AKPSWRNFTYEELA---VATDYFNPENMIGKGGHAEVYKGVLINGET------------- 177
Query 627 LVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
V +K L + F +++ V+H + A + G
Sbjct 178 ------------VAIKKLMSHAKEEEERVSDFLSELGIIAHVNHPNAARLRGFSSDRG-L 224
Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNI 740
V EY +G L L + + VA +A LSYL N + ++H ++ NI
Sbjct 225 HFVLEYAPYGSLASMLFGSEECLEWKIRYKVALGIADGLSYLHNACPRRIIHRDIKASNI 284
Query 741 LLARLGLAEGTSPFIKLSDPGVGL-GALSREERV-----ERIPWLAPECLPGGANSLSTA 794
LL A+ +SD G+ + V +LAPE G +
Sbjct 285 LLNHDYEAQ-------ISDFGLAKWLPENWPHHVVFPIEGTFGYLAPEYFMHGI--VDEK 335
Query 795 MDKWGFGATLLEICFDGEA--------------PLQSRSPSEKEHFYQRQHRLPEPSCPQ 840
+D + FG LLEI A P ++ E + + +
Sbjct 336 IDVFAFGVLLLEIITSRRAVDTASRQSIVAWAKPFLEKNSMEDIVDPRLGNMFNPTEMQR 395
Query 841 LATLTSQCLTYEPTQRPSFRTI 862
+ S C+ + RP +
Sbjct 396 VMLTASMCVHHIAAMRPDMTRL 417
>sp|Q54G43|SHKE_DICDI Dual specificity protein kinase shkE OS=Dictyostelium
discoideum OX=44689 GN=shkE PE=3 SV=1
Length=710
Score = 217 bits (552), Expect = 7e-58, Method: Composition-based stats.
Identities = 62/274 (23%), Positives = 112/274 (41%), Gaps = 26/274 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G +GKV K +K E++I++ ++H +++
Sbjct 243 LGGGAYGKVYKATCRGKKVAVKVP-----KKQTLSESELKSFKNEVEIMKQIFHPNVVLC 297
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI---GLAQLLLFAQQICEGMAYLHA-QH 1018
G C G+ + +V E + L + + L + + G+ +LH +
Sbjct 298 LGACTKPGK--VMIVSELMQ-TDLEKLIHSSEVEPPPLYERMKMCLDAALGINWLHGICN 354
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
IHRDL N+++ D+ VKIGDFG ++ + G + + APE + +++F
Sbjct 355 IIHRDLKLANLMISKDKTVKIGDFGFSQVIKTGTTLSDQKGP-KGTALYMAPEVMMKHEF 413
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
+DV+SFG+ LYE+ T + I + R P PD
Sbjct 414 NEKADVYSFGLILYEMATCEELFPEYSEIDPFYDAICN-------------KKLRPPIPD 460
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
P + L++ CW+ + + RP+F + + V
Sbjct 461 SFPKSLKTLIQKCWDHDPNKRPSFNEVTQRMNEV 494
Score = 187 bits (474), Expect = 6e-48, Method: Composition-based stats.
Identities = 52/316 (16%), Positives = 112/316 (35%), Gaps = 47/316 (15%)
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
R+S R ++ + + LG G VY+ R + K
Sbjct 215 EKKRSSSRHSGPPEIPPEEIKFD--VKTDLLGGGAYGKVYKATCRGKKVAVKVPKKQTL- 271
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+F +M Q+ H ++ G C + + +
Sbjct 272 -----------------------SESELKSFKNEVEIMKQIFHPNVVLCLGACTKPGKVM 308
Query 685 MVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLEN-KNLVHGNVCGRNILL 742
+V+E ++ L+ + P+ +M + A +++L N++H ++ N+++
Sbjct 309 IVSELMQ-TDLEKLIHSSEVEPPPLYERMKMCLDAALGINWLHGICNIIHRDLKLANLMI 367
Query 743 ARLGLAEGTSPFIKLSDPGV------GLGALSREERVERIPWLAPECLPGGANSLSTAMD 796
++ +K+ D G G ++ ++APE + + + D
Sbjct 368 SK-------DKTVKIGDFGFSQVIKTGTTLSDQKGPKGTALYMAPEVMM--KHEFNEKAD 418
Query 797 KWGFGATLLEICFDGE-APLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEP 853
+ FG L E+ E P S + ++ R +P+ L TL +C ++P
Sbjct 419 VYSFGLILYEMATCEELFPEYSEIDPFYDAICNKKLRPPIPDSFPKSLKTLIQKCWDHDP 478
Query 854 TQRPSFRTILRDLTRL 869
+RPSF + + + +
Sbjct 479 NKRPSFNEVTQRMNEV 494
>sp|P43292|SRK2G_ARATH Serine/threonine-protein kinase SRK2G OS=Arabidopsis
thaliana OX=3702 GN=SRK2G PE=1 SV=2
Length=353
Score = 207 bits (527), Expect = 7e-58, Method: Composition-based stats.
Identities = 75/276 (27%), Positives = 117/276 (42%), Gaps = 26/276 (9%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
++DLG G+FG L + T E+VA+K + + G + +EI R+
Sbjct 1 MDKYDVVKDLGAGNFGVARLL----RHKDTKELVAMKYI--ERGRKIDENVAREIINHRS 54
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012
L H +II++K L +VMEY G L D + A+ F QQ+ G+
Sbjct 55 LKHPNIIRFKEVILTPTH--LAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVD 112
Query 1013 YLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
Y H+ HRDL N LLD L+KI DFG +K + R + +P + AP
Sbjct 113 YCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSK---SSILHSRPKSTVGTPA-YIAP 168
Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
E L ++ +DVWS GVTLY +L + P I + ++ + +
Sbjct 169 EVLSRREYDGKHADVWSCGVTLYVMLVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYV- 227
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
E HL+ + T ++ R T + +
Sbjct 228 ---------HISQECKHLLSRIFVTNSAKRITLKEI 254
Score = 147 bits (372), Expect = 2e-37, Method: Composition-based stats.
Identities = 43/250 (17%), Positives = 79/250 (32%), Gaps = 17/250 (7%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
R + + V +K ++ I + H ++ V + +V EY
Sbjct 22 RHKDTKELVAMKYIERG-RKIDENVAREIINHRSLKHPNIIRFKEVILTPTHLAIVMEYA 80
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L + G A QQL + Y + + H ++ N LL
Sbjct 81 SGGELFDRI-CTAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLD-----GS 134
Query 751 TSPFIKLSDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+P +K+ D G ++ + V ++APE L D W G TL +
Sbjct 135 PAPLLKICDFGYSKSSILHSRPKSTVGTPAYIAPEVLSRREYD-GKHADVWSCGVTLYVM 193
Query 808 CFDGEAPLQSRSPSE----KEHFYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRT 861
P + Q+++P+ + L S+ +R + +
Sbjct 194 LVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYVHISQECKHLLSRIFVTNSAKRITLKE 253
Query 862 ILRDLTRLQP 871
I L+
Sbjct 254 IKNHPWYLKN 263
>sp|Q91ZR4|NEK8_MOUSE Serine/threonine-protein kinase Nek8 OS=Mus
musculus OX=10090 GN=Nek8 PE=1 SV=1
Length=698
Score = 216 bits (551), Expect = 7e-58, Method: Composition-based stats.
Identities = 66/269 (25%), Positives = 120/269 (45%), Gaps = 30/269 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V L ++V +K + + + R + E +L+ L H ++I+
Sbjct 10 VGRGAFGIVHLCLRKA----DQKLVILKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIE 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018
Y + +K+L + MEY P G+L +++ + + +L F QI + ++H
Sbjct 66 YYENFLE--DKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHL 123
Query 1019 YIHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL +N+LLD +VKIGDFG++K + + Y V + +PE +
Sbjct 124 ILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTV----VGTPCYISPELCEGKP 179
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ SD+W+ G LYEL + + ++ L L + G P
Sbjct 180 YNQKSDIWALGCVLYELASLKRAFEAANLPALVL---------------KIMSGTFAPIS 224
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
D+ E+ L+ + E + RP +++
Sbjct 225 DRYSPELRQLVLSLLSLEPAQRPPLSHIM 253
Score = 164 bits (416), Expect = 1e-40, Method: Composition-based stats.
Identities = 45/292 (15%), Positives = 101/292 (35%), Gaps = 39/292 (13%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ ++ +G+G V+ + + + V+LK +
Sbjct 1 MEKYERIRVVGRGAFGIVHLCLRKAD------------------------QKLVILKQIP 36
Query 646 PSHH--DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
+ A ++ ++H ++ + + ++ EY G L ++++
Sbjct 37 VEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRC 96
Query 704 GH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ + Q+ AL ++ ++H ++ +NILL + +K+ D G+
Sbjct 97 NSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKH------RMVVKIGDFGI 150
Query 763 GLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
S+ V +++PE G + D W G L E+ A +
Sbjct 151 SKILSSKSKAYTVVGTPCYISPELCEG--KPYNQKSDIWALGCVLYELASLKRAFEAANL 208
Query 820 PSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P+ + + P+L L L+ EP QRP I+ ++
Sbjct 209 PALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIR 260
>sp|Q501Q9|MK15_XENLA Mitogen-activated protein kinase 15 OS=Xenopus
laevis OX=8355 GN=mapk15 PE=1 SV=1
Length=586
Score = 214 bits (545), Expect = 7e-58, Method: Composition-based stats.
Identities = 68/299 (23%), Positives = 118/299 (39%), Gaps = 27/299 (9%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEID 949
+ + LG+G +G V + + +GE+VAVK + A +EI
Sbjct 8 DHISQKYDIKKRLGKGAYGIV----WKAIDRKSGEIVAVKKIFDAFRNRTDAQRTFREIM 63
Query 950 ILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQI 1007
L+ H +IIK Q +K + LV E++ L + + ++ + Q+
Sbjct 64 FLQEFGEHPNIIKLLNVIRAQNDKDIYLVFEHME-TDLHAVIKKGNLLKDIHMRYILYQL 122
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--VREDGDSPV 1065
+ ++H+ + IHRD N+LLD D LVK+ DFGLA+++ + E + +
Sbjct 123 LKATKFIHSGNVIHRDQKPSNILLDGDCLVKLCDFGLARSLYQIQEDVGNPALTEYVATR 182
Query 1066 FWYAPECLK-EYKFYYASDVWSFGVTLYELLTHCDSS----------------QSPPTKF 1108
++ APE L ++ D+WS G L E+L + P +
Sbjct 183 WYRAPEILLASNRYTKGVDMWSVGCILGEMLLGKPLFPGTSTINQIERIMSIIEPPTHED 242
Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ I G + R++ + P CP E L+ R T E +
Sbjct 243 IVSIKSEYGASVISRMSSKHKVPMAELFPASCPREALDLLSKLLVFNPGKRLTAEEALE 301
Score = 135 bits (340), Expect = 1e-31, Method: Composition-based stats.
Identities = 44/269 (16%), Positives = 89/269 (33%), Gaps = 52/269 (19%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
++ ++ H + +I LG+G V++ DR
Sbjct 1 MSGPEVEDHISQKYDIK--KRLGKGAYGIVWKAI------------------------DR 34
Query 634 GQELRVVLKVLD---PSHHDIALAFYETASLMSQV-SHTHLAFVHGVCV--RGPENIMVT 687
V +K + + D F + + H ++ + V + +V
Sbjct 35 KSGEIVAVKKIFDAFRNRTDAQRTF-REIMFLQEFGEHPNIIKLLNVIRAQNDKDIYLVF 93
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
E++E L +++ + + + QL A ++ + N++H + NILL
Sbjct 94 EHME-TDLHAVIKKGNLLKDIHMRY-ILYQLLKATKFIHSGNVIHRDQKPSNILLD---- 147
Query 748 AEGTSPFIKLSDPGVGLGALSREERVERIP---------WLAPECLPGGANSLSTAMDKW 798
+KL D G+ +E V + APE L +N + +D W
Sbjct 148 ---GDCLVKLCDFGLARSLYQIQEDVGNPALTEYVATRWYRAPEILL-ASNRYTKGVDMW 203
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFY 827
G L E+ + + ++ E
Sbjct 204 SVGCILGEMLLGKPLFPGTSTINQIERIM 232
>sp|E9Q3S4|M3K19_MOUSE Mitogen-activated protein kinase kinase
kinase 19 OS=Mus musculus OX=10090 GN=Map3k19 PE=3 SV=1
Length=1311
Score = 223 bits (567), Expect = 7e-58, Method: Composition-based stats.
Identities = 70/287 (24%), Positives = 120/287 (42%), Gaps = 29/287 (10%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG-----PQHRSGW 944
+ K LG G +G V G+++AVK + D +
Sbjct 1037 NHEEAIFWTKGEILGRGAYGTVYCG-----LTSLGQLIAVKQVALDTSDKLATEKEYRKL 1091
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLF 1003
++E+D+L+ L H +I+ Y G C + E +L + ME+VP GS+ + R + +
Sbjct 1092 QEEVDLLKALKHVNIVAYLGTCLE--ENTLSIFMEFVPGGSISSIINRFGPLPEMVFCKY 1149
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE---GHEYYRVRED 1060
+QI +G+AYLH +HRD+ NV+L ++K+ DFG AK + + + +
Sbjct 1150 TRQILQGVAYLHDNCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHSDMLKS 1209
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
+W APE + E + SD+WS G T++E+ T P + +
Sbjct 1210 MRGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKP----PLASMDRMAAMFYIGAH 1265
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
RG P P + ++ C + RP+ L+
Sbjct 1266 ---------RGLMPPLPARFSEPAADFVRLCLTRDQHERPSALQLLK 1303
Score = 180 bits (457), Expect = 1e-44, Method: Composition-based stats.
Identities = 69/328 (21%), Positives = 113/328 (34%), Gaps = 53/328 (16%)
Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614
E + L S ++LN + F T+ LG+G VY G +
Sbjct 1017 YDEENFLTSNEKKTLSDKSLNHEEAIFW-------TKGEILGRGAYGTVYCGLTSLGQLI 1069
Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674
++ +D D L ++ E L+ + H ++
Sbjct 1070 AVKQVALDTSDKLATEKEY-------------------RKLQEEVDLLKALKHVNIVAYL 1110
Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGN 734
G C+ + E+V G + + G +P +Q+ ++YL + +VH +
Sbjct 1111 GTCLEENTLSIFMEFVPGGSISSII-NRFGPLPEMVFCKYTRQILQGVAYLHDNCVVHRD 1169
Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGL--------GALSR--EERVERIPWLAPECL 784
+ G N++L G+ IKL D G G S + W+APE +
Sbjct 1170 IKGNNVMLMPTGI-------IKLIDFGCAKRLAWAGLNGTHSDMLKSMRGTPYWMAPEVI 1222
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-----LPEPSCP 839
+ D W G T+ E+ G+ PL S FY HR LP
Sbjct 1223 --NESGYGRKSDIWSIGCTVFEMA-TGKPPLASMD-RMAAMFYIGAHRGLMPPLPARFSE 1278
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLT 867
A CLT + +RPS +L+
Sbjct 1279 PAADFVRLCLTRDQHERPSALQLLKHSF 1306
>sp|G5EFU0|PK2_CAEEL Serine/threonine-protein kinase pak-2 OS=Caenorhabditis
elegans OX=6239 GN=pak-2 PE=2 SV=1
Length=522
Score = 212 bits (540), Expect = 7e-58, Method: Composition-based stats.
Identities = 67/301 (22%), Positives = 116/301 (39%), Gaps = 23/301 (8%)
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918
T + + + L + +GEG G V
Sbjct 193 PSTPQAMRQQPKCTEGVSDEEFRNALKFVVDGTDPRSDLTDYKQIGEGSTGVVEAAY--- 249
Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978
T ++VAVK + Q R E+ ILR H +I+++ + L +VM
Sbjct 250 -KISTKQIVAVKRMNLRK-QQRRELLFNEVSILRQYQHPNIVRF--FSSHLVDDELWVVM 305
Query 979 EYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038
E++ GSL D + + Q+ ++Q+ + +LHA+ IHRD+ + ++LL D VK
Sbjct 306 EFMEGGSLTDIVTATRMTEPQIATISRQVLGALDFLHARKVIHRDIKSDSILLKRDGTVK 365
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
+ DFG + E R +W A E + + +D+WSFG+ L E++
Sbjct 366 LTDFGFCGQLSE---EVPRRRSLVGTPYWTAAEVIAREPYDTRADIWSFGIMLIEMVEGE 422
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158
+ Q + R+ + E R R K E+ L+ +C + +
Sbjct 423 PPFFND-----------QPFQAMKRIRD--EHEARFSRHAKVSVELSELLSHCIVKDVNK 469
Query 1159 R 1159
R
Sbjct 470 R 470
Score = 186 bits (473), Expect = 4e-49, Method: Composition-based stats.
Identities = 59/338 (17%), Positives = 111/338 (33%), Gaps = 45/338 (13%)
Query 539 RAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQG 598
R + PQ G L + + ++T +G+G
Sbjct 182 RTTTPQLQPKSPSTPQAMRQQPKC-TEGVSDEEFRNALKFVVDGTDPRSDLTDYKQIGEG 240
Query 599 TRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYET 658
+ V + V +K ++ +
Sbjct 241 STGVV------------------------EAAYKISTKQIVAVKRMNLRKQQRRELLFNE 276
Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQL 718
S++ Q H ++ + E +V E++E G L + R + +++Q+
Sbjct 277 VSILRQYQHPNIVRFFSSHLVDDELWVVMEFMEGGSLTDIVTATR--MTEPQIATISRQV 334
Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERVE 774
AL +L + ++H ++ +ILL R G +KL+D G + R V
Sbjct 335 LGALDFLHARKVIHRDIKSDSILLKRDG-------TVKLTDFGFCGQLSEEVPRRRSLVG 387
Query 775 RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-- 832
W A E + T D W FG L+E+ +GE P + P + + +H
Sbjct 388 TPYWTAAEVIA--REPYDTRADIWSFGIMLIEMV-EGEPPFFNDQPFQAMKRIRDEHEAR 444
Query 833 --LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+L+ L S C+ + +R + +LR
Sbjct 445 FSRHAKVSVELSELLSHCIVKDVNKRWPAKDLLRHPFF 482
>sp|Q61526|ERBB3_MOUSE Receptor tyrosine-protein kinase erbB-3
OS=Mus musculus OX=10090 GN=Erbb3 PE=1 SV=2
Length=1339
Score = 223 bits (567), Expect = 7e-58, Method: Composition-based stats.
Identities = 89/272 (33%), Positives = 139/272 (51%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + V +K ++ G Q + + +L H HI++
Sbjct 713 LGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRL 772
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C SLQLV +Y+PLGSL D++ +H ++G LL + QI +GM YL +
Sbjct 773 LGLC---PGSSLQLVTQYLPLGSLLDHVRQHRETLGPQLLLNWGVQIAKGMYYLEEHSMV 829
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLA RNV+L + V++ DFG+A +P + + + +P+ W A E + K+ +
Sbjct 830 HRDLALRNVMLKSPSQVQVADFGVADLLPP-DDKQLLHSEAKTPIKWMALESIHFGKYTH 888
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + + + +LLE+GERL +P C
Sbjct 889 QSDVWSYGVTVWELMTFG--------------AEPYAGLRLAEIPDLLEKGERLAQPQIC 934
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW + + RPTF+ L +
Sbjct 935 TIDVYMVMVKCWMIDENIRPTFKELANEFTRM 966
Score = 201 bits (511), Expect = 4e-51, Method: Composition-based stats.
Identities = 67/366 (18%), Positives = 131/366 (36%), Gaps = 39/366 (11%)
Query 520 GRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQL 579
+ + L+ G + R + L + +++
Sbjct 638 SKPHLVIAVTVGLTVIFLILGGSFLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKANKV 697
Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639
+ E+ +L LG G V++G EG ++ V
Sbjct 698 LARIFKETELRKLKVLGSGVFGTVHKGIWIPEGESI--------------------KIPV 737
Query 640 VLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+KV+ D S A + + + H H+ + G+C G +VT+Y+ G L
Sbjct 738 CIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLCP-GSSLQLVTQYLPLGSLLDH 796
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
+R+ R + + Q+A + YLE ++VH ++ RN++L + ++++
Sbjct 797 VRQHRETLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVML-------KSPSQVQVA 849
Query 759 DPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812
D GV + E I W+A E + G + D W +G T+ E+ G
Sbjct 850 DFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFG--KYTHQSDVWSYGVTVWELMTFGA 907
Query 813 APLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
P +E ++ RL P+ + + +C + RP+F+ + + TR+
Sbjct 908 EPYAGLRLAEIPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMA 967
Query 871 PHNLAD 876
Sbjct 968 RDPPRY 973
>sp|Q751E8|PHO85_EREGS Negative regulator of the PHO system OS=Eremothecium
gossypii (strain ATCC 10895 / CBS 109.51 / FGSC
9923 / NRRL Y-1056) OX=284811 GN=PHO85 PE=3 SV=2
Length=301
Score = 205 bits (521), Expect = 7e-58, Method: Composition-based stats.
Identities = 69/314 (22%), Positives = 132/314 (42%), Gaps = 40/314 (13%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950
+ K++ LG G + V Y N TG VA+K +K D S +EI +
Sbjct 1 MTSTSQFKQLERLGNGTYATV----YKGLNKTTGLYVALKEVKLDSEEGTPSTAIREISL 56
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-------SIGLAQLLLF 1003
++ L HE+I++ E L LV E++ L+ ++ + L+ + F
Sbjct 57 MKELKHENIVRLYDVI--HTENKLTLVFEFMDN-DLKKFMDSRLDREMPRGLELSLVKYF 113
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
Q+ +G+A+ H +HRDL +N+L++N +K+GDFGLA+A
Sbjct 114 QWQLLQGVAFCHENRILHRDLKPQNLLINNKGQLKLGDFGLARAFGIP---VNTFSSEVV 170
Query 1064 PVFWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTK-----FLELIGIAQG 1117
+++ AP+ L + + + D+WS G L E++ E +G
Sbjct 171 TLWYRAPDVLMGSRTYCTSIDIWSCGCILAEMIMGKALFPGTNDDEQLKLIFETMGTPTE 230
Query 1118 QMTVLRLTELLERGERLP-RP-------------DKCPCEVYHLMKNCWETEASFRPTFE 1163
Q T + +++L + ++P P ++ + +L++ + S R + +
Sbjct 231 Q-TWVGVSQLPKYNPQIPLYPNKDIKQLLQATTKEQISDVLVNLIQGLLQLNPSMRLSAQ 289
Query 1164 NLIPILKTVHEKYQ 1177
+ + E+Y
Sbjct 290 QALSH--PLFEEYH 301
Score = 166 bits (419), Expect = 3e-44, Method: Composition-based stats.
Identities = 46/270 (17%), Positives = 97/270 (36%), Gaps = 43/270 (16%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ QL LG GT VY+G + G L V LK +
Sbjct 3 STSQFKQLERLGNGTYATVYKGLNKTTG------------------------LYVALKEV 38
Query 645 DPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---- 699
+ SLM ++ H ++ ++ V + +V E++++ L ++
Sbjct 39 KLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDN-DLKKFMDSRL 97
Query 700 -RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
R + ++ QL +++ ++H ++ +N+L+ G +KL
Sbjct 98 DREMPRGLELSLVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNKGQ-------LKLG 150
Query 759 DPGVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
D G+ + V + + AP+ L G+ + T++D W G L E+
Sbjct 151 DFGLARAFGIPVNTFSSEVVTLWYRAPDVLM-GSRTYCTSIDIWSCGCILAEMIMGKALF 209
Query 815 LQSRSPSEKEHFYQRQHRLPEPSCPQLATL 844
+ + + ++ E + ++ L
Sbjct 210 PGTNDDEQLKLIFETMGTPTEQTWVGVSQL 239
>sp|Q6U1I9|SGK1_CHICK Serine/threonine-protein kinase Sgk1 OS=Gallus
gallus OX=9031 GN=SGK1 PE=2 SV=1
Length=432
Score = 209 bits (533), Expect = 8e-58, Method: Composition-based stats.
Identities = 66/338 (20%), Positives = 118/338 (35%), Gaps = 29/338 (9%)
Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885
F +++ ++AT + C E + + +
Sbjct 28 FMKQRRMGLNDFIQKIATNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINLG 87
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSG 943
S ++ +G+G FGKV L + + AVK L KA +
Sbjct 88 PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEE----QFYAVKVLQKKAILKKKEEKH 143
Query 944 WKQEID-ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLL 1001
E + +L+ + H ++ Q L V++Y+ G L +L R +
Sbjct 144 IMSERNVLLKNVKHPFLVGLH--FSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRAR 201
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
+A +I + YLH+ + ++RDL N+LLD+ + + DFGL K E E+
Sbjct 202 FYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCK---ENIEHNGTTSTF 258
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
+ APE L + + D W G LYE+L + T
Sbjct 259 CGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPF--------------YSRNTA 304
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+L + +L HL++ + + + R
Sbjct 305 EMYDNILNKPLQLK--PNITNSARHLLEGLLQKDRTKR 340
Score = 162 bits (410), Expect = 1e-41, Method: Composition-based stats.
Identities = 68/314 (22%), Positives = 109/314 (35%), Gaps = 45/314 (14%)
Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
PQ E N + + +NL S + L +G+G+ V
Sbjct 63 QPQEPELMN-ANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKV-------- 113
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETAS-LMSQVSH 667
+ R + +E +KVL + L+ V H
Sbjct 114 ----------------LLARHKAEEQFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 157
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
L +H + V +Y+ G L L+RER + + A ++ASAL YL +
Sbjct 158 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARF-YAAEIASALGYLHS 216
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREERVERIPWLAPEC 783
N+V+ ++ NILL G I L+D G+ + + +LAPE
Sbjct 217 LNIVYRDLKPENILLDSQG-------HIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEV 269
Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPSCPQLA 842
L +D W GA L E+ G P SR+ +E + + +L
Sbjct 270 LH--KQPYDRTVDWWCLGAVLYEML-YGLPPFYSRNTAEMYDNILNKPLQLKPNITNSAR 326
Query 843 TLTSQCLTYEPTQR 856
L L + T+R
Sbjct 327 HLLEGLLQKDRTKR 340
>sp|P32485|HOG1_YEAST Mitogen-activated protein kinase HOG1 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=HOG1 PE=1 SV=2
Length=435
Score = 209 bits (533), Expect = 8e-58, Method: Composition-based stats.
Identities = 62/309 (20%), Positives = 107/309 (35%), Gaps = 29/309 (9%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-K 933
+ + +G G FG V T+ T + VA+K + K
Sbjct 1 MTTNEEFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVC----SATDTLTSQPVAIKKIMK 56
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993
+E+ +L+ L HE++I + E + V E L L
Sbjct 57 PFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLED-IYFVTEL-QGTDLHRLLQTR 114
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ + F QI G+ Y+H+ IHRDL N+L++ + +KI DFGLA+
Sbjct 115 PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMT 174
Query 1054 YYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTK 1107
Y S ++ APE + K+ D+WS G E++ +
Sbjct 175 GY------VSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSI 228
Query 1108 FLELIGIAQGQMTVLRLTELLER-----GERLPRP-----DKCPCEVYHLMKNCWETEAS 1157
+L+G + +E + R P P + L++ +
Sbjct 229 ITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPK 288
Query 1158 FRPTFENLI 1166
R T + +
Sbjct 289 KRITAADAL 297
Score = 137 bits (345), Expect = 4e-33, Method: Composition-based stats.
Identities = 36/213 (17%), Positives = 69/213 (32%), Gaps = 18/213 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
V+E R G + D V +K ++ P +A Y
Sbjct 13 FGTVFEITNRYNDLNPVGMGAF---GLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYR 69
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H +L + + + + VTE + L L+ + +
Sbjct 70 ELKLLKHLRHENLICLQDIFLSPLEDIYFVTEL-QGTDLHRLLQTR--PLEKQFVQYFLY 126
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + ++H ++ NIL+ + +K+ D G+ V
Sbjct 127 QILRGLKYVHSAGVIHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 179
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ APE + +D W G E+
Sbjct 180 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEMI 211
>sp|Q9SKB2|SBIR1_ARATH Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein
kinase SOBIR1 OS=Arabidopsis thaliana
OX=3702 GN=SOBIR1 PE=1 SV=1
Length=641
Score = 215 bits (548), Expect = 8e-58, Method: Composition-based stats.
Identities = 71/294 (24%), Positives = 117/294 (40%), Gaps = 29/294 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-------------KADCGPQHRSGWKQEID 949
+G G G+V +N G+++AVK + + + + EI+
Sbjct 353 IGRGGCGEVFKAELPGSN---GKIIAVKKVIQPPKDADELTDEDSKFLNKKMRQIRSEIN 409
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFA 1004
+ + H +++ + LV EY+ GSL+D L + A
Sbjct 410 TVGHIRHRNLLPLLAHVSRP--ECHYLVYEYMEKGSLQDILTDVQAGNQELMWPARHKIA 467
Query 1005 QQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
I G+ YLH IHRDL NVLLD+D +I DFGLAKA+P+ +
Sbjct 468 LGIAAGLEYLHMDHNPRIIHRDLKPANVLLDDDMEARISDFGLAKAMPDAVTHITTSHVA 527
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQM 1119
V + APE + +KF D++SFGV L L+ S T + LI + +
Sbjct 528 -GTVGYIAPEFYQTHKFTDKCDIYSFGVILGILVIGKLPSDEFFQHTDEMSLIKWMRNII 586
Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173
T + ++ D+ V + C + RP +++ +L +
Sbjct 587 TSENPSLAIDPKLMDQGFDEQMLLVLKIACYCTLDDPKQRPNSKDVRTMLSQIK 640
Score = 185 bits (469), Expect = 1e-47, Method: Composition-based stats.
Identities = 58/345 (17%), Positives = 117/345 (34%), Gaps = 56/345 (16%)
Query 564 MRGARASPRTLNLSQL-----SFHRVDQKE-ITQLSHLGQGTRTNVYEGRL-RVEGSGDP 616
+RG+ P S L ++ +E + L +G+G V++ L G
Sbjct 316 IRGSEKPPGPSIFSPLIKKAEDLAFLENEEALASLEIIGRGGCGEVFKAELPGSNGKIIA 375
Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676
+ + D K L+ + + + H +L +
Sbjct 376 VKKVIQPPKDADELTDEDS------KFLNKK----MRQIRSEINTVGHIRHRNLLPLLAH 425
Query 677 CVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYL---ENKNL 730
R + +V EY+E G L L + G+ + W + +A +A+ L YL N +
Sbjct 426 VSRPECHYLVYEYMEKGSLQDILTDVQAGNQELMWPARHKIALGIAAGLEYLHMDHNPRI 485
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPECL 784
+H ++ N+LL ++SD G+ ++ + ++APE
Sbjct 486 IHRDLKPANVLLD-------DDMEARISDFGLAKAMPDAVTHITTSHVAGTVGYIAPEFY 538
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLA-- 842
+ + D + FG L + + +++ + + P LA
Sbjct 539 QT--HKFTDKCDIYSFGVILGILVIGKLPSDEFFQHTDEMSLIKWMRNIITSENPSLAID 596
Query 843 -TLTSQ---------------CLTYEPTQRPSFRTILRDLTRLQP 871
L Q C +P QRP+ + + L++++
Sbjct 597 PKLMDQGFDEQMLLVLKIACYCTLDDPKQRPNSKDVRTMLSQIKH 641
>sp|Q6ZI44|SAPK6_ORYSJ Serine/threonine-protein kinase SAPK6 OS=Oryza
sativa subsp. japonica OX=39947 GN=SAPK6 PE=1 SV=1
Length=365
Score = 207 bits (527), Expect = 8e-58, Method: Composition-based stats.
Identities = 72/270 (27%), Positives = 109/270 (40%), Gaps = 30/270 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
D+G G+FG L N T E+VA+K + G + +EI R+L H +II+
Sbjct 9 DIGSGNFGVARLM----RNRETKELVAMKYIPR--GLKIDENVAREIINHRSLRHPNIIR 62
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+K L +VMEY G L D + + F QQ+ G++Y H
Sbjct 63 FKEVVLTPTH--LAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYCHFMQIC 120
Query 1021 HRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N LLD +KI DFG +K + + + APE L ++
Sbjct 121 HRDLKLENTLLDGSPAPRLKICDFGYSK----SSLLHSKPKSTVGTPAYIAPEVLSRREY 176
Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSP--PTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+DVWS GVTLY +L + P P F + IG ++ ++P
Sbjct 177 DGKMADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIG------------RIVSIQYKIP 224
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
+ L+ + + R T +
Sbjct 225 EYVHISQDCRQLLSRIFVANPAKRITIREI 254
Score = 155 bits (391), Expect = 1e-39, Method: Composition-based stats.
Identities = 51/295 (17%), Positives = 84/295 (28%), Gaps = 41/295 (14%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ L +G G R+R + V +K +
Sbjct 1 MEKYELLKDIGSGNFG------------------------VARLMRNRETKELVAMKYI- 35
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
P I + H ++ V + +V EY G L + G
Sbjct 36 PRGLKIDENVAREIINHRSLRHPNIIRFKEVVLTPTHLAIVMEYAAGGELFDRI-CSAGR 94
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
QQL +SY + H ++ N LL +P +K+ D G
Sbjct 95 FSEDESRYFFQQLICGVSYCHFMQICHRDLKLENTLLD-----GSPAPRLKICDFGYSKS 149
Query 766 AL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+L + V ++APE L D W G TL + P
Sbjct 150 SLLHSKPKSTVGTPAYIAPEVLSRREYD-GKMADVWSCGVTLYVMLVGAYPFEDPDDPKN 208
Query 823 KEH----FYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
Q+++PE L S+ P +R + R I ++
Sbjct 209 FRKTIGRIVSIQYKIPEYVHISQDCRQLLSRIFVANPAKRITIREIRNHPWFMKN 263
>sp|Q91819|AURAB_XENLA Aurora kinase A-B OS=Xenopus laevis OX=8355
GN=aurka-b PE=2 SV=3
Length=408
Score = 209 bits (531), Expect = 8e-58, Method: Composition-based stats.
Identities = 62/312 (20%), Positives = 114/312 (37%), Gaps = 30/312 (10%)
Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910
+ P + + + T+ + + R LG+G FG
Sbjct 94 PNENRNPQQTSHSSTPNMEKKGSTDQGKTLAVPKEEGKKKQWCLEDFEIGRPLGKGKFGN 153
Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHIIKYKGCCED 968
V L + ++A+K L + ++E++I L H +I++ G D
Sbjct 154 VYL----ARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHD 209
Query 969 QGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027
+ L+++Y P G L L + + L+ +Q+ E + Y H++ IHRD+
Sbjct 210 A--CRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLAEALLYCHSKKVIHRDIKPE 267
Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087
N+LL ++ +KI DFG + P R + + PE ++ D+WS
Sbjct 268 NLLLGSNGELKIADFGWSVHAPSSR-----RTTLCGTLDYLPPEMIEGRMHDEKVDLWSL 322
Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
GV YE L ++ Q T R++++ P E L
Sbjct 323 GVLCYEFLVGKPPFETD-----------THQETYRRISKV-----EFQYPPYVSEEAKDL 366
Query 1148 MKNCWETEASFR 1159
+ + + R
Sbjct 367 VSKLLKHNPNHR 378
Score = 183 bits (464), Expect = 6e-49, Method: Composition-based stats.
Identities = 56/301 (19%), Positives = 108/301 (36%), Gaps = 41/301 (14%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
++ LG+G NVY R+R + + LKVL
Sbjct 138 EDFEIGRPLGKGKFGNVYLA------------------------RERESKFILALKVLFK 173
Query 647 SHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
S + + + S + H ++ ++G ++ +Y G L L++
Sbjct 174 SQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDACRVYLILDYAPGGELFRELQK-C 232
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ +QLA AL Y +K ++H ++ N+LL G++ +K++D G
Sbjct 233 TRFDDQRSALYIKQLAEALLYCHSKKVIHRDIKPENLLL-------GSNGELKIADFGWS 285
Query 764 LGALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ A S R + +L PE + G + +D W G E G+ P ++ +
Sbjct 286 VHAPSSRRTTLCGTLDYLPPEMIEGRMH--DEKVDLWSLGVLCYEFLV-GKPPFETDTHQ 342
Query 822 EK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880
E + + + P + L S+ L + P R + +L ++
Sbjct 343 ETYRRISKVEFQYPPYVSEEAKDLVSKLLKHNPNHRLPLKGVLEHPWIVKNSQQPKKKDE 402
Query 881 N 881
Sbjct 403 P 403
>sp|P34112|CDK1_DICDI Cyclin-dependent kinase 1 OS=Dictyostelium
discoideum OX=44689 GN=cdk1 PE=2 SV=1
Length=296
Score = 205 bits (521), Expect = 8e-58, Method: Composition-based stats.
Identities = 73/285 (26%), Positives = 120/285 (42%), Gaps = 26/285 (9%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+K+ LGEG +GKV Y TG MVA+K ++ + S +EI +L+ + H
Sbjct 10 YQKLEKLGEGTYGKV----YKAKEKATGRMVALKKIRLE-DDGVPSTALREISLLKEVPH 64
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLH 1015
+++ Q L LV EY+ L+ Y+ QL+ + Q+ +G+AY H
Sbjct 65 PNVVSLFDVLHCQN--RLYLVFEYLDQ-DLKKYMDSVPALCPQLIKSYLYQLLKGLAYSH 121
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRDL +N+L+D +K+ DFGLA+AV RV +++ APE L
Sbjct 122 GHRILHRDLKPQNLLIDRQGALKLADFGLARAVSIP---VRVYTHEIVTLWYRAPEVLLG 178
Query 1076 YK-FYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM--TVLRLTEL 1127
K + D+WS G E+L + ++G + V +L E
Sbjct 179 SKSYSVPVDMWSVGCIFGEMLNKKPLFSGDCEIDQIFRIFRVLGTPDDSIWPGVTKLPEY 238
Query 1128 LERGERLP------RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ P +C L+ + E S R + + +
Sbjct 239 VSTFPNWPGQPYNKIFPRCEPLALDLIAKMLQYEPSKRISAKEAL 283
Score = 155 bits (392), Expect = 1e-40, Method: Composition-based stats.
Identities = 50/283 (18%), Positives = 91/283 (32%), Gaps = 38/283 (13%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+L LG+GT VY+ + + G V LK +
Sbjct 12 KLEKLGEGTYGKVYKAKEKATGRM------------------------VALKKIRLEDDG 47
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
+ SL+ +V H ++ + V +V EY++ L ++ P
Sbjct 48 VPSTALREISLLKEVPHPNVVSLFDVLHCQNRLYLVFEYLDQ-DLKKYMDSVPALCP-QL 105
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG----A 766
QL L+Y ++H ++ +N+L+ R G +KL+D G+
Sbjct 106 IKSYLYQLLKGLAYSHGHRILHRDLKPQNLLIDRQGA-------LKLADFGLARAVSIPV 158
Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
+ + + APE L G+ S S +D W G E+ +
Sbjct 159 RVYTHEIVTLWYRAPEVLL-GSKSYSVPVDMWSVGCIFGEMLNKKPLFSGDCEIDQIFRI 217
Query 827 YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869
++ + P + L T+ + I L
Sbjct 218 FRVLGTPDDSIWPGVTKLPEYVSTFPNWPGQPYNKIFPRCEPL 260
>sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo
sapiens OX=9606 GN=RPS6KA1 PE=1 SV=2
Length=735
Score = 217 bits (553), Expect = 8e-58, Method: Composition-based stats.
Identities = 66/259 (25%), Positives = 113/259 (44%), Gaps = 24/259 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961
LG+G FGKV L T +G + A+K LK + R K E DIL + H ++K
Sbjct 68 LGQGSFGKVFLVR-KVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVK 126
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020
Q E L L+++++ G L L + + + ++ G+ +LH+ I
Sbjct 127 LHYAF--QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGII 184
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
+RDL N+LLD + +K+ DFGL+K E ++ + V + APE + +
Sbjct 185 YRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKKAYSFCGTVEYMAPEVVNRQGHSH 241
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
++D WS+GV ++E+LT Q K + + +L P
Sbjct 242 SADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILK----------------AKLGMPQFL 285
Query 1141 PCEVYHLMKNCWETEASFR 1159
E L++ ++ + R
Sbjct 286 STEAQSLLRALFKRNPANR 304
Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats.
Identities = 62/272 (23%), Positives = 102/272 (38%), Gaps = 29/272 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHII 960
+G G + + + TN AVK + + +EI+IL H +II
Sbjct 423 TIGVGSYSECKRCVHKATN----MEYAVKVIDKS-----KRDPSEEIEILLRYGQHPNII 473
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHY 1019
K +D K + LV E + G L D + R + I + + YLH+Q
Sbjct 474 TLKDVYDDG--KHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGV 531
Query 1020 IHRDLAARNVL-LDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRDL N+L +D ++I DFG AK + + + APE LK
Sbjct 532 VHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMT---PCYTANFVAPEVLKR 588
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ D+WS G+ LY +L + P+ E I +T + + G
Sbjct 589 QGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEI------LTRIGSGKFTLSGGNW- 641
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ L+ + R T + ++
Sbjct 642 --NTVSETAKDLVSKMLHVDPHQRLTAKQVLQ 671
Score = 169 bits (427), Expect = 6e-42, Method: Composition-based stats.
Identities = 54/282 (19%), Positives = 102/282 (36%), Gaps = 39/282 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ D L LGQG+ V+ + D L +
Sbjct 55 EKADPSHFELLKVLGQGSFGKVFL----------VRKVTRPDSGHLY-----------AM 93
Query 642 KVLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
KVL + + +++ V+H + +H + ++ +++ G L L
Sbjct 94 KVLKKATLKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRL 153
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+E K +A +LA L +L + +++ ++ NILL G IKL+D
Sbjct 154 SKEVMFTEEDVKFYLA-ELALGLDHLHSLGIIYRDLKPENILLDEEG-------HIKLTD 205
Query 760 PGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ A+ E++ + ++APE + +S S D W +G + E+ G P
Sbjct 206 FGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS--ADWWSYGVLMFEML-TGSLPF 262
Query 816 QSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQR 856
Q + E + +P+ + +L P R
Sbjct 263 QGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPANR 304
Score = 150 bits (379), Expect = 5e-36, Method: Composition-based stats.
Identities = 50/277 (18%), Positives = 93/277 (34%), Gaps = 26/277 (9%)
Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664
+ + +G E + + + +KV+D S D + E ++ +
Sbjct 410 KNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPS----EEIEILLR 465
Query 665 V-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723
H ++ + V G +VTE + G L + R++ V + +
Sbjct 466 YGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKF-FSEREASFVLHTIGKTVE 524
Query 724 YLENKNLVHGNVCGRNIL-LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL--- 779
YL ++ +VH ++ NIL + G E +++ D G + + +
Sbjct 525 YLHSQGVVHRDLKPSNILYVDESGNPE----CLRICDFGFAKQLRAENGLLMTPCYTANF 580
Query 780 -APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL---QSRSPSEKE-HFYQRQHRL- 833
APE L D W G L + G P S +P E + L
Sbjct 581 VAPEVLK--RQGYDEGCDIWSLGILLYTMLA-GYTPFANGPSDTPEEILTRIGSGKFTLS 637
Query 834 ---PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
L S+ L +P QR + + +L+
Sbjct 638 GGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPW 674
>sp|O64629|AUR3_ARATH Serine/threonine-protein kinase Aurora-3
OS=Arabidopsis thaliana OX=3702 GN=AUR3 PE=2 SV=1
Length=288
Score = 204 bits (520), Expect = 8e-58, Method: Composition-based stats.
Identities = 61/280 (22%), Positives = 116/280 (41%), Gaps = 29/280 (10%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEI 948
+ + R LG+G FG+V L + +VA+K + + +++ ++E+
Sbjct 16 QWSLADFEIGRPLGKGKFGRVYL----AREAKSKYIVALKVIFKEQIEKYKIHHQLRREM 71
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQI 1007
+I +L H +I++ G D + + L++EY G L L ++ + Q + +
Sbjct 72 EIQTSLRHPNILRLFGWFHDN--ERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASL 129
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ +AY H + IHRD+ N+LLD++ +KI DFG + R+ + +
Sbjct 130 SQALAYCHGKCVIHRDIKPENLLLDHEGRLKIADFGWSVQ------SSNKRKTMCGTLDY 183
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE ++ YA D W+ G+ YE L ++ K +
Sbjct 184 LAPEMVENRDHDYAVDNWTLGILCYEFLYGNPPFEAESQKDT--------------FKRI 229
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L+ P E +L+ + S R + E ++
Sbjct 230 LKIDLSFPLTPNVSEEAKNLISQLLVKDPSKRLSIEKIMQ 269
Score = 176 bits (446), Expect = 6e-48, Method: Composition-based stats.
Identities = 56/298 (19%), Positives = 103/298 (35%), Gaps = 42/298 (14%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ LG+G VY R+ + V LKV+
Sbjct 21 DFEIGRPLGKGKFGRVYLA------------------------REAKSKYIVALKVIFKE 56
Query 648 HHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ I + + + H ++ + G ++ EY G L L++ G
Sbjct 57 QIEKYKIHHQLRREMEIQTSLRHPNILRLFGWFHDNERIFLILEYAHGGELYGVLKQN-G 115
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763
H+ L+ AL+Y K ++H ++ N+LL G +K++D G
Sbjct 116 HLTEQQAATYIASLSQALAYCHGKCVIHRDIKPENLLLDHEGR-------LKIADFGWSV 168
Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
+ R+ + +LAPE + + A+D W G E G P ++ S +
Sbjct 169 QSSNKRKTMCGTLDYLAPEMVENRDHDY--AVDNWTLGILCYE-FLYGNPPFEAESQKDT 225
Query 824 EHFYQR---QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878
+ L + L SQ L +P++R S I++ ++ + V
Sbjct 226 FKRILKIDLSFPLTPNVSEEAKNLISQLLVKDPSKRLSIEKIMQHPWIVKNADPKGVC 283
>sp|Q63531|KS6A1_RAT Ribosomal protein S6 kinase alpha-1 OS=Rattus
norvegicus OX=10116 GN=Rps6ka1 PE=1 SV=1
Length=735
Score = 217 bits (553), Expect = 8e-58, Method: Composition-based stats.
Identities = 66/259 (25%), Positives = 112/259 (43%), Gaps = 24/259 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961
LG+G FGKV L T G + A+K LK + R K E DIL + H ++K
Sbjct 68 LGQGSFGKVFLVR-KVTRPDNGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVK 126
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020
Q E L L+++++ G L L + + + ++ G+ +LH+ I
Sbjct 127 LHYAF--QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGII 184
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
+RDL N+LLD + +K+ DFGL+K E ++ + V + APE + +
Sbjct 185 YRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKKAYSFCGTVEYMAPEVVNRQGHTH 241
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
++D WS+GV ++E+LT Q K + + +L P
Sbjct 242 SADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILK----------------AKLGMPQFL 285
Query 1141 PCEVYHLMKNCWETEASFR 1159
E L++ ++ + R
Sbjct 286 STEAQSLLRALFKRNPANR 304
Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats.
Identities = 63/272 (23%), Positives = 101/272 (37%), Gaps = 29/272 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHII 960
+G G + + TN AVK + + +EI+IL H +II
Sbjct 423 TIGVGSYSVCKRCVHKATN----MEYAVKVIDKS-----KRDPSEEIEILLRYGQHPNII 473
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHY 1019
K +D K + LV E + G L D + R + I + + YLH+Q
Sbjct 474 TLKDVYDDS--KHVYLVTELMRGGELLDKILRQKFFSEREASFVLYTISKTVEYLHSQGV 531
Query 1020 IHRDLAARNVL-LDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRDL N+L +D ++I DFG AK + + + APE LK
Sbjct 532 VHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMT---PCYTANFVAPEVLKR 588
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ D+WS GV LY +L + P+ E I +T + + G
Sbjct 589 QGYDEGCDIWSLGVLLYTMLAGYTPFANGPSDTPEEI------LTRISSGKFTLSGGNW- 641
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ L+ + R T + ++
Sbjct 642 --NTVSETAKDLVSKMLHVDPHQRLTAKQVLQ 671
Score = 169 bits (429), Expect = 4e-42, Method: Composition-based stats.
Identities = 53/282 (19%), Positives = 102/282 (36%), Gaps = 39/282 (14%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+ D L LGQG+ V+ + D L +
Sbjct 55 EKADPSHFELLKVLGQGSFGKVFL----------VRKVTRPDNGHLY-----------AM 93
Query 642 KVLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699
KVL + + +++ V+H + +H + ++ +++ G L L
Sbjct 94 KVLKKATLKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRL 153
Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759
+E K +A +LA L +L + +++ ++ NILL G IKL+D
Sbjct 154 SKEVMFTEEDVKFYLA-ELALGLDHLHSLGIIYRDLKPENILLDEEG-------HIKLTD 205
Query 760 PGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ A+ E++ + ++APE + ++ S D W +G + E+ G P
Sbjct 206 FGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHS--ADWWSYGVLMFEML-TGSLPF 262
Query 816 QSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQR 856
Q + E + +P+ + +L P R
Sbjct 263 QGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPANR 304
Score = 150 bits (380), Expect = 5e-36, Method: Composition-based stats.
Identities = 52/293 (18%), Positives = 97/293 (33%), Gaps = 26/293 (9%)
Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664
+ + +G E + + + +KV+D S D + E ++ +
Sbjct 410 KNLVFSDGYIVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKSKRDPS----EEIEILLR 465
Query 665 V-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723
H ++ + V +VTE + G L + R++ V ++ +
Sbjct 466 YGQHPNIITLKDVYDDSKHVYLVTELMRGGELLDKILRQKF-FSEREASFVLYTISKTVE 524
Query 724 YLENKNLVHGNVCGRNIL-LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL--- 779
YL ++ +VH ++ NIL + G E +++ D G + + +
Sbjct 525 YLHSQGVVHRDLKPSNILYVDESGNPE----CLRICDFGFAKQLRAENGLLMTPCYTANF 580
Query 780 -APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL---QSRSPSEKE-HFYQRQHRL- 833
APE L D W G L + G P S +P E + L
Sbjct 581 VAPEVLK--RQGYDEGCDIWSLGVLLYTMLA-GYTPFANGPSDTPEEILTRISSGKFTLS 637
Query 834 ---PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
L S+ L +P QR + + +L+ Q L + D
Sbjct 638 GGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLPQSQLSHQD 690
>sp|Q39025|MPK5_ARATH Mitogen-activated protein kinase 5 OS=Arabidopsis
thaliana OX=3702 GN=MPK5 PE=2 SV=2
Length=376
Score = 207 bits (528), Expect = 8e-58, Method: Composition-based stats.
Identities = 73/323 (23%), Positives = 123/323 (38%), Gaps = 34/323 (11%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KA 934
+ + +Y+ IR +G G +G V + T E +A+K + KA
Sbjct 22 HGGRYFQYNVYGNLFEVSNKYVPPIRPIGRGAYGFVCA----AVDSETHEEIAIKKIGKA 77
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL---QLVMEYVPLGSLRDYLP 991
+EI +LR L HE+++ K ++ +V E + L +
Sbjct 78 FDNKVDAKRTLREIKLLRHLEHENVVVIKDIIRPPKKEDFVDVYIVFELMD-TDLHQIIR 136
Query 992 -RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
S+ F QI G+ Y+H+ + +HRDL N+LL+++ +KI DFGLA+ E
Sbjct 137 SNQSLNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNSNCDLKITDFGLARTTSE 196
Query 1051 GHEYYRVREDGDSPVFWYAPE-CLKEYKFYYASDVWSFGVTLYELLTHCDSSQ------- 1102
+ ++ APE L ++ A DVWS G E++T
Sbjct 197 TEY----MTEYVVTRWYRAPELLLNSSEYTSAIDVWSVGCIFAEIMTREPLFPGKDYVHQ 252
Query 1103 ---------SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153
SP LE + A + V L + + P + L++
Sbjct 253 LKLITELIGSPDGASLEFLRSANARKYVKELPKFPRQNFSARFPSMNSTAI-DLLEKMLV 311
Query 1154 TEASFRPTFENLI--PILKTVHE 1174
+ R T E + P L +H+
Sbjct 312 FDPVKRITVEEALCYPYLSALHD 334
Score = 131 bits (329), Expect = 2e-31, Method: Composition-based stats.
Identities = 38/238 (16%), Positives = 80/238 (34%), Gaps = 44/238 (18%)
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
V K + + +G+G V D + +K
Sbjct 37 EVSNKYVPPIRPIGRGAYGFVC------------------------AAVDSETHEEIAIK 72
Query 643 VLDPSHHDIALAF--YETASLMSQVSHTHLAFVHGVCVRGPE-----NIMVTEYVEHGPL 695
+ + + A L+ + H ++ + + + +V E ++ L
Sbjct 73 KIGKAFDNKVDAKRTLREIKLLRHLEHENVVVIKDIIRPPKKEDFVDVYIVFELMD-TDL 131
Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755
+R + + Q+ L Y+ + N++H ++ N+LL ++ +
Sbjct 132 HQIIRSNQ-SLNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLN-------SNCDL 183
Query 756 KLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810
K++D G+ E E V + APE L ++ ++A+D W G EI
Sbjct 184 KITDFGLARTTSETEYMTEYVVTRWYRAPELLLN-SSEYTSAIDVWSVGCIFAEIMTR 240
>sp|Q62799|ERBB3_RAT Receptor tyrosine-protein kinase erbB-3 OS=Rattus
norvegicus OX=10116 GN=Erbb3 PE=1 SV=3
Length=1339
Score = 223 bits (567), Expect = 8e-58, Method: Composition-based stats.
Identities = 89/272 (33%), Positives = 139/272 (51%), Gaps = 20/272 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
LG G FG V + P + V +K ++ G Q + + +L H HI++
Sbjct 713 LGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRL 772
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYI 1020
G C SLQLV +Y+PLGSL D++ +H ++G LL + QI +GM YL +
Sbjct 773 LGLC---PGSSLQLVTQYLPLGSLLDHVKQHRETLGPQLLLNWGVQIAKGMYYLEEHSMV 829
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
HRDLA RNV+L + V++ DFG+A +P + + + +P+ W A E + K+ +
Sbjct 830 HRDLALRNVMLKSPSQVQVADFGVADLLPP-DDKQLLHSEAKTPIKWMALESIHFGKYTH 888
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
SDVWS+GVT++EL+T + + + +LLE+GERL +P C
Sbjct 889 QSDVWSYGVTVWELMTFG--------------AEPYAGLRLAEIPDLLEKGERLAQPQIC 934
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172
+VY +M CW + + RPTF+ L +
Sbjct 935 TIDVYMVMVKCWMIDENIRPTFKELANEFTRM 966
Score = 199 bits (505), Expect = 2e-50, Method: Composition-based stats.
Identities = 62/301 (21%), Positives = 118/301 (39%), Gaps = 39/301 (13%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
+ E+ +L LG G V++G EG ++ V +KV+
Sbjct 703 KETELRKLKVLGSGVFGTVHKGIWIPEGESI--------------------KIPVCIKVI 742
Query 645 -DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
D S A + + + H H+ + G+C G +VT+Y+ G L +++ R
Sbjct 743 EDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLCP-GSSLQLVTQYLPLGSLLDHVKQHR 801
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ + Q+A + YLE ++VH ++ RN++L + ++++D GV
Sbjct 802 ETLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVML-------KSPSQVQVADFGVA 854
Query 764 LGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ E I W+A E + G + D W +G T+ E+ G P
Sbjct 855 DLLPPDDKQLLHSEAKTPIKWMALESIHFG--KYTHQSDVWSYGVTVWELMTFGAEPYAG 912
Query 818 RSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
+E ++ RL P+ + + +C + RP+F+ + + TR+
Sbjct 913 LRLAEIPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPR 972
Query 876 D 876
Sbjct 973 Y 973
>sp|Q9C098|DCLK3_HUMAN Serine/threonine-protein kinase DCLK3 OS=Homo
sapiens OX=9606 GN=DCLK3 PE=1 SV=2
Length=648
Score = 215 bits (548), Expect = 8e-58, Method: Composition-based stats.
Identities = 69/277 (25%), Positives = 108/277 (39%), Gaps = 27/277 (10%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
+ + R +G+G+F V + + T + A+K + EI I+++L
Sbjct 355 HYETGRVIGDGNFAVVK----ECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLS 410
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYL 1014
H +I+K E E + L++EYV G L D + L +C+ + ++
Sbjct 411 HPNIVKLHEVYETDME--IYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHM 468
Query 1015 HAQHYIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070
H + +HRDL N+L+ D +K+ DFGLAK V R + AP
Sbjct 469 HDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHV------VRPIFTVCGTPTYVAP 522
Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
E L E + D+W+ GV LY LL +SP EL I Q E L
Sbjct 523 EILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGH-----FEFL-- 575
Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
P D L+ + R T ++
Sbjct 576 ---PPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQ 609
Score = 161 bits (407), Expect = 1e-39, Method: Composition-based stats.
Identities = 62/324 (19%), Positives = 110/324 (34%), Gaps = 45/324 (14%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
P+ N R + PR + + + + +G G V E
Sbjct 325 PKTRPEENKPE-RPSGRKPRPMGIIAANVEK----HYETGRVIGDGNFAVVKE------- 372
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE-TASLMSQVSHTHLA 671
R R +K++D S + ++ +SH ++
Sbjct 373 -----------------CRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIV 415
Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731
+H V E ++ EYV+ G L + E P ++ L AL ++ +K++V
Sbjct 416 KLHEVYETDMEIYLILEYVQGGDLFDAII-ESVKFPEPDAALMIMDLCKALVHMHDKSIV 474
Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-EERVERIPWLAPECLPGGANS 790
H ++ N+L+ R E S +KL+D G+ + ++APE L
Sbjct 475 HRDLKPENLLVQRN---EDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSE--KG 529
Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-------HRLPEPSCPQLAT 843
+D W G L I G P +S + E F Q +
Sbjct 530 YGLEVDMWAAGVILY-ILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKD 588
Query 844 LTSQCLTYEPTQRPSFRTILRDLT 867
L S+ L +P +R + +L+
Sbjct 589 LVSRLLVVDPKKRYTAHQVLQHPW 612
>sp|Q6IP76|AKT2B_XENLA RAC-beta serine/threonine-protein kinase
B OS=Xenopus laevis OX=8355 GN=akt2-b PE=2 SV=1
Length=485
Score = 211 bits (537), Expect = 8e-58, Method: Composition-based stats.
Identities = 66/260 (25%), Positives = 98/260 (38%), Gaps = 28/260 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960
LG+G FGKV L TG A+K L+ + + E +L+ H +
Sbjct 162 LGKGTFGKVILV----REKATGLYYAMKILRKEVIIAKDEVAHTLTESRVLQNTKHPFLT 217
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019
K Q L VMEY G L +L R + + +I + YLH+++
Sbjct 218 GLKYAF--QTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRNV 275
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
++RD+ N++LD D VKI DFGL K EG + APE L++ +
Sbjct 276 VYRDIKLENLMLDKDGHVKITDFGLCK---EGITDGATMRTFCGTPEYLAPEVLEDNDYG 332
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
A D W GV +YE++ Q +L R PR
Sbjct 333 RAVDWWGLGVVMYEMMCGRLPF--------------YNQDHERLFELILMEETRFPR--T 376
Query 1140 CPCEVYHLMKNCWETEASFR 1159
E L+ + + R
Sbjct 377 LSPEAKSLLAGLLKKDPKQR 396
Score = 168 bits (425), Expect = 4e-43, Method: Composition-based stats.
Identities = 57/283 (20%), Positives = 97/283 (34%), Gaps = 43/283 (15%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
+V + L LG+GT V + R++ L +
Sbjct 149 PKVTMNDFDYLKLLGKGTFGKV------------------------ILVREKATGLYYAM 184
Query 642 KVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
K+L + ++ H L + V EY G L
Sbjct 185 KILRKEVIIAKDEVAHTLTESRVLQNTKHPFLTGLKYAFQTSDRLCFVMEYANGGELFFH 244
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
L RER ++ SAL YL ++N+V+ ++ N++L + G +K++
Sbjct 245 LSRER-VFTEDRARFYGAEIVSALEYLHSRNVVYRDIKLENLMLDKDG-------HVKIT 296
Query 759 DPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
D G+ ++ +LAPE L N A+D WG G + E+ G P
Sbjct 297 DFGLCKEGITDGATMRTFCGTPEYLAPEVLED--NDYGRAVDWWGLGVVMYEMMC-GRLP 353
Query 815 LQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
++ + R P P+ +L + L +P QR
Sbjct 354 FYNQDHERLFELILMEETRFPRTLSPEAKSLLAGLLKKDPKQR 396
>sp|Q8TDC3|BRSK1_HUMAN Serine/threonine-protein kinase BRSK1 OS=Homo
sapiens OX=9606 GN=BRSK1 PE=1 SV=2
Length=778
Score = 218 bits (554), Expect = 9e-58, Method: Composition-based stats.
Identities = 71/279 (25%), Positives = 117/279 (42%), Gaps = 29/279 (10%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDI 950
+ + + LG+G G V L + TG+ VA+K + + ++EI I
Sbjct 29 QYVGPYRLEKTLGKGQTGLVKLG----VHCITGQKVAIKIVNREKLSESVLMKVEREIAI 84
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICE 1009
L+ + H H++K E++ K L LV+E+V G L DYL + + + F +QI
Sbjct 85 LKLIEHPHVLKLHDVYENK--KYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVS 142
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ + H+ HRDL N+LLD ++I DFG+A + E +
Sbjct 143 ALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASL----QVGDSLLETSCGSPHYAC 198
Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE +K K+ +D+WS GV L+ LL + +L E +
Sbjct 199 PEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDD---------------NLRQLLEKV 243
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+RG P P + L++ E E R + E +
Sbjct 244 KRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQK 281
Score = 169 bits (428), Expect = 7e-42, Method: Composition-based stats.
Identities = 54/329 (16%), Positives = 101/329 (31%), Gaps = 44/329 (13%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647
LG+G V G + G +V +K+++
Sbjct 35 RLEKTLGKGQTGLVKLGVHCITGQ------------------------KVAIKIVNREKL 70
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
+ + +++ + H H+ +H V +V E+V G L +L ++G +
Sbjct 71 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYL-VKKGRLT 129
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
+Q+ SAL + + ++ H ++ N+LL I+++D G+ +
Sbjct 130 PKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKN-------NIRIADFGMASLQV 182
Query 768 SR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
E + PE + G D W G L + G P + +
Sbjct 183 GDSLLETSCGSPHYACPEVIKGEKYD-GRRADMWSCGVILFALLV-GALPFDDDNLRQLL 240
Query 825 HFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
+R +P P +L + EP +R S I + L + D
Sbjct 241 EKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAP 300
Query 884 SPASDPTVFHKRYLKKIRDLGE----GHF 908
L G F
Sbjct 301 GRRVAMRSLPSNGELDPDVLESMASLGCF 329
>sp|O75011|NAK1_SCHPO Serine/threonine-protein kinase nak1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=nak1 PE=1 SV=1
Length=652
Score = 215 bits (548), Expect = 9e-58, Method: Composition-based stats.
Identities = 65/270 (24%), Positives = 113/270 (42%), Gaps = 30/270 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH---EHI 959
+G G +G V Y + T E VA+K L D S ++E+ +L L E+I
Sbjct 16 VGRGSYGAV----YRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQSDVENI 71
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
IKY G +L ++M+Y GS+R + I + L ++ + + ++H
Sbjct 72 IKYHGSYLVGT--NLWIIMDYCHGGSVRTLMEAGPISEPCISLILRETLQALKFIHHAGI 129
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK-F 1078
IHRD+ A N+L+ VK+ DFG+A + R R +W APE +++ + +
Sbjct 130 IHRDIKAANILVSMSGNVKLCDFGVAAELNINR---RKRITFIGTPYWMAPEVIRDGQEY 186
Query 1079 YYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+D+WS G+T YE+ T ++ P + + LI + L
Sbjct 187 NVMADIWSLGITAYEIATGSPPHAKEDPFRAVYLIAHTAPPRLNGNFSAL---------- 236
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + +C + R L+
Sbjct 237 ------LKEFIASCLQDVPQRRLDSSELLK 260
Score = 177 bits (448), Expect = 5e-45, Method: Composition-based stats.
Identities = 56/311 (18%), Positives = 108/311 (35%), Gaps = 45/311 (14%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD-PSH 648
T+L +G+G+ VY G + + V +K+L+ +
Sbjct 11 TKLELVGRGSYGAVYRGICNL------------------------TKETVAIKILNLDTD 46
Query 649 HDIALAFYETASLMSQVSH---THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
D + +++S++ ++ HG + G ++ +Y G + + E G
Sbjct 47 EDEVSDIQKEVAVLSELKQSDVENIIKYHGSYLVGTNLWIIMDYCHGGSVRTLM--EAGP 104
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763
+ ++ ++ AL ++ + ++H ++ NIL++ S +KL D GV
Sbjct 105 ISEPCISLILRETLQALKFIHHAGIIHRDIKAANILVS-------MSGNVKLCDFGVAAE 157
Query 764 --LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ R + W+APE + G + D W G T EI G P P
Sbjct 158 LNINRRKRITFIGTPYWMAPEVIRDG-QEYNVMADIWSLGITAYEIA-TGSPPHAKEDPF 215
Query 822 EKEHF--YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
+ + RL L + CL P +R +L+ Q ++
Sbjct 216 RAVYLIAHTAPPRLNGNFSALLKEFIASCLQDVPQRRLDSSELLKSKFIKQYSRMSISEL 275
Query 880 VNPDSPASDPT 890
N
Sbjct 276 TNVVKRYDTWQ 286
>sp|Q07176|MMK1_MEDSA Mitogen-activated protein kinase homolog
MMK1 OS=Medicago sativa OX=3879 GN=MMK1 PE=1 SV=1
Length=387
Score = 207 bits (528), Expect = 1e-57, Method: Composition-based stats.
Identities = 72/321 (22%), Positives = 118/321 (37%), Gaps = 31/321 (10%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KA 934
+ + +Y I +G+G +G V N T E VAVK + A
Sbjct 34 HGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAH----NSETNEHVAVKKIANA 89
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK---SLQLVMEYVPLGSLRDYLP 991
+EI +LR + HE+++ + + + + E + L +
Sbjct 90 FDNKIDAKRTLREIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMD-TDLHQIIR 148
Query 992 -RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050
++ F QI G+ Y+H+ + +HRDL N+LL+ + +KI DFGLA+ E
Sbjct 149 SNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSE 208
Query 1051 GHEYYRVREDGDSPVFWYAPE-CLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-----SP 1104
+ ++ APE L + A DVWS G EL+
Sbjct 209 TD----FMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 264
Query 1105 PTKFLELIGIAQGQ------MTVLRLTELLERGERLPRPDKCP---CEVYHLMKNCWETE 1155
+ELIG R L R +K P E L++ +
Sbjct 265 LRLLMELIGTPSEDDLGFLNENAKRYIRQLPPYRRQSFQEKFPHVHPEAIDLVEKMLTFD 324
Query 1156 ASFRPTFENLI--PILKTVHE 1174
R T E+ + P L ++H+
Sbjct 325 PRKRITVEDALAHPYLTSLHD 345
Score = 126 bits (317), Expect = 7e-30, Method: Composition-based stats.
Identities = 32/219 (15%), Positives = 75/219 (34%), Gaps = 22/219 (10%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF--YE 657
N++E + + + + V +K + + + A
Sbjct 44 FGNIFE--VTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLR 101
Query 658 TASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
L+ + H ++ + + + + E ++ L +R + +
Sbjct 102 EIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMD-TDLHQIIRSNQA-LSEEHCQ 159
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770
Q+ L Y+ + N++H ++ N+LL + +K+ D G+ +
Sbjct 160 YFLYQILRGLKYIHSANVLHRDLKPSNLLLN-------ANCDLKICDFGLARVTSETDFM 212
Query 771 -ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
E V + APE L ++ + A+D W G +E+
Sbjct 213 TEYVVTRWYRAPELLLN-SSDYTAAIDVWSVGCIFMELM 250
>sp|Q38868|CDPK9_ARATH Calcium-dependent protein kinase 9 OS=Arabidopsis
thaliana OX=3702 GN=CPK9 PE=1 SV=1
Length=541
Score = 212 bits (540), Expect = 1e-57, Method: Composition-based stats.
Identities = 78/357 (22%), Positives = 131/357 (37%), Gaps = 30/357 (8%)
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
P + + + P T ++ L+
Sbjct 12 MKPQQNGNTTRSVEVGVTNQDPPSYTPQARTTQQPEKPGSVNSQPPPWRAAAAAPGLSPK 71
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KAD 935
T +S + K + ++LG G FG L T + TG+ A K++ K
Sbjct 72 TTTKSNSILENAFEDVKLFYTLGKELGRGQFGVTYLC----TENSTGKKYACKSISKKKL 127
Query 936 CGPQHRSGWKQEIDILRTLYH-EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRH 993
+ ++EI I++ L +I+++KG ED EK++ LVME G L D + +
Sbjct 128 VTKADKDDMRREIQIMQHLSGQPNIVEFKGAYED--EKAVNLVMELCAGGELFDRIIAKG 185
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPE 1050
+QI + H +HRDL N LL D L+K DFGL+ + E
Sbjct 186 HYTERAAASVCRQIVNVVKICHFMGVLHRDLKPENFLLSSKDEKALIKATDFGLSVFIEE 245
Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110
G Y D ++ APE L+ ++ D+WS G+ LY LL+ + K +
Sbjct 246 GKVY----RDIVGSAYYVAPEVLR-RRYGKEVDIWSAGIILYILLSGVPPFWAETEKGI- 299
Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
I +G + E P P L++ + R + +++
Sbjct 300 FDAILEGHIDF----------ESQPWP-SISSSAKDLVRRMLTADPKRRISAADVLQ 345
Score = 137 bits (345), Expect = 2e-32, Method: Composition-based stats.
Identities = 51/311 (16%), Positives = 96/311 (31%), Gaps = 40/311 (13%)
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
+ + ++ ++ + +F V T LG+G Y +G K +
Sbjct 69 SPKTTTKSNSILENAFEDVKLF-YTLGKELGRGQFGVTY--LCTENSTGKKYACKSISKK 125
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS-HTHLAFVHGVCVRGPENI 684
LV D+ +M +S ++ G
Sbjct 126 KLVTKADK-------------------DDMRREIQIMQHLSGQPNIVEFKGAYEDEKAVN 166
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+V E G L + +GH V +Q+ + + ++H ++ N LL+
Sbjct 167 LVMELCAGGELFDRIIA-KGHYTERAAASVCRQIVNVVKICHFMGVLHRDLKPENFLLSS 225
Query 745 LGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFG 801
+ IK +D G+ + + + V ++APE L +D W G
Sbjct 226 ----KDEKALIKATDFGLSVFIEEGKVYRDIVGSAYYVAPEVLR---RRYGKEVDIWSAG 278
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQH-----RLPEPSCPQLATLTSQCLTYEPTQR 856
L I G P + + H + L + LT +P +R
Sbjct 279 IILY-ILLSGVPPFWAETEKGIFDAILEGHIDFESQPWPSISSSAKDLVRRMLTADPKRR 337
Query 857 PSFRTILRDLT 867
S +L+
Sbjct 338 ISAADVLQHPW 348
>sp|Q9P7I2|KCC1_SCHPO Calcium/calmodulin-dependent protein kinase
type I OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)
OX=284812 GN=cmk1 PE=1 SV=1
Length=335
Score = 206 bits (523), Expect = 1e-57, Method: Composition-based stats.
Identities = 69/298 (23%), Positives = 108/298 (36%), Gaps = 28/298 (9%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
+ R LG G + V + + T +M A K + + + K EI IL+
Sbjct 28 PCKYRVGRVLGGGTYATVR----EAVHIETNKMYAAKIMNKKMMEKKQDFVKNEIAILKR 83
Query 954 LY--HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEG 1010
+ H +I+ E +L L+ E G L D + + S A +
Sbjct 84 VSYEHPNILHLVDFFE--TVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSA 141
Query 1011 MAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
+ YLH +HRDL N+L D + + I DFGL+ E +YY + +P +
Sbjct 142 VKYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSH-FYEDSQYYMLMTACGTPE-Y 199
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE + + D+W+ GV Y LL+ P Q+ V+
Sbjct 200 MAPEVFRRTGYGKPVDMWAIGVITYFLLSGYTPFARP------------SQVEVIEAILA 247
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAPSV 1183
E P +K C E + S R T + + P L P+V
Sbjct 248 NEYTFNDPCWSGISETAKDFIKKCLENDPSKRLTAADALKHPFLSEKRPATSNLLPNV 305
Score = 145 bits (367), Expect = 7e-37, Method: Composition-based stats.
Identities = 42/282 (15%), Positives = 83/282 (29%), Gaps = 45/282 (16%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ LG GT V E K+++
Sbjct 30 KYRVGRVLGGGTYATVREAVHIETNKMY------------------------AAKIMNKK 65
Query 648 HHDIALAF-YETASLMSQVS--HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
+ F +++ +VS H ++ + ++TE G L + +G
Sbjct 66 MMEKKQDFVKNEIAILKRVSYEHPNILHLVDFFETVNNLYLITELATGGELFDRI-CAKG 124
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
A + + SA+ YL + +VH ++ N+L ++ + + ++D G+
Sbjct 125 SFYEADAAALMRTTTSAVKYLHDNGIVHRDLKPENLL----YRSKDPNSDLLIADFGLSH 180
Query 765 GALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+ + ++APE +D W G + G P S
Sbjct 181 FYEDSQYYMLMTACGTPEYMAPEVFR--RTGYGKPVDMWAIGVITYFLLS-GYTPFARPS 237
Query 820 PSEKEHF-----YQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
E Y +CL +P++R
Sbjct 238 QVEVIEAILANEYTFNDPCWSGISETAKDFIKKCLENDPSKR 279
>sp|P24923|CDC21_MEDSA Cell division control protein 2 homolog
1 (Fragment) OS=Medicago sativa OX=3879 GN=CDC2A PE=2 SV=1
Length=291
Score = 204 bits (519), Expect = 1e-57, Method: Composition-based stats.
Identities = 71/287 (25%), Positives = 124/287 (43%), Gaps = 33/287 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHII 960
+GEG +G V Y + T E +A+K ++ + + S +EI +L+ + H +I+
Sbjct 6 KIGEGTYGVV----YKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIV 61
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI---GLAQLLLFAQQICEGMAYLHAQ 1017
+ + +K L LV EY+ L L+ ++ Q+ +F Q+ G+AY H+
Sbjct 62 RLQDVV--HSDKRLYLVFEYLDL-DLKKHMDSSPEFIKDPRQVKMFLYQMLCGIAYCHSH 118
Query 1018 HYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+HRDL +N+L+D +K+ DFGLA+A R +++ APE L
Sbjct 119 RVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIP---VRTFTHEVVTLWYRAPEILLGS 175
Query 1077 K-FYYASDVWSFGVTLYEL-----LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130
+ + DVWS G E+ L+ DS K ++G T +T L +
Sbjct 176 RHYSTPVDVWSVGCIFAEMANRRPLSPGDSEIDELFKIFRILGTPNED-TWPGVTSLPDF 234
Query 1131 GERLPR----------PDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
PR P+ P + L+ + + + R T + +
Sbjct 235 KSTFPRWPSKDLATVVPNLEPAGL-DLLNSMLCLDPTKRITARSAVE 280
Score = 160 bits (404), Expect = 2e-42, Method: Composition-based stats.
Identities = 45/262 (17%), Positives = 92/262 (35%), Gaps = 39/262 (15%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--VLDPS 647
+ +G+GT VY+ RDR + LK L+
Sbjct 2 ENVEKIGEGTYGVVYKA------------------------RDRVTNETIALKKIRLEQE 37
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
+ SL+ ++ H ++ + V +V EY++ L + +
Sbjct 38 DEGVPSTAIREISLLKEMQHRNIVRLQDVVHSDKRLYLVFEYLDL-DLKKHMDSSPEFIK 96
Query 708 MAWKMVV-AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG- 765
++ + Q+ ++Y + ++H ++ +N+L+ R + +KL+D G+
Sbjct 97 DPRQVKMFLYQMLCGIAYCHSHRVLHRDLKPQNLLIDRR------TNSLKLADFGLARAF 150
Query 766 ---ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ V + + APE L G+ ST +D W G E+ E
Sbjct 151 GIPVRTFTHEVVTLWYRAPEILL-GSRHYSTPVDVWSVGCIFAEMANRRPLSPGDSEIDE 209
Query 823 KEHFYQRQHRLPEPSCPQLATL 844
++ E + P + +L
Sbjct 210 LFKIFRILGTPNEDTWPGVTSL 231
>sp|Q5QN75|M2K1_ORYSJ Mitogen-activated protein kinase kinase
1 OS=Oryza sativa subsp. japonica OX=39947 GN=MKK1 PE=1 SV=1
Length=355
Score = 206 bits (525), Expect = 1e-57, Method: Composition-based stats.
Identities = 73/320 (23%), Positives = 133/320 (42%), Gaps = 23/320 (7%)
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920
+ + LQ + + + L+ I+ +G+G G V L +
Sbjct 35 ELRLNQRGLQLISEETADEPQSTNLKVEDVQLSMDDLEMIQVIGKGSGGIVQLV----RH 90
Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980
G + A+K ++ + R QE+ I + + HI+ G + LV+EY
Sbjct 91 KWVGTLYALKGIQMNIQEAVRKQIVQELKINQATQNAHIVLCHQSFYHNG--VIYLVLEY 148
Query 981 VPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHA-QHYIHRDLAARNVLLDNDRLVK 1038
+ GSL D + + +I L + +Q+ EG+ YLH +H IHRD+ N+L++ VK
Sbjct 149 MDRGSLADIIKQVKTILEPYLAVLCKQVLEGLLYLHHERHVIHRDIKPSNLLVNRKGEVK 208
Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098
I DFG++ + R+ + APE + + Y SD+WS G+ + E C
Sbjct 209 ITDFGVSAVLASSMGQ---RDTFVGTYNYMAPERISGSSYDYKSDIWSLGLVILE----C 261
Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP-DKCPCEVYHLMKNCWETEAS 1157
+ P + +G ++ L E + P D+ E + +C + + +
Sbjct 262 AIGRFPY-----IPSEGEGWLSFYELLEAIVDQPPPSAPADQFSPEFCAFISSCIQKDPA 316
Query 1158 FRPTFENLI--PILKTVHEK 1175
R + L+ P +K +K
Sbjct 317 ERMSASELLNHPFIKKFEDK 336
Score = 166 bits (419), Expect = 2e-43, Method: Composition-based stats.
Identities = 53/320 (17%), Positives = 114/320 (36%), Gaps = 49/320 (15%)
Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621
+I P++ NL + ++ ++ + +G+G+ V R + G+ +G
Sbjct 45 LISEETADEPQSTNLK-VEDVQLSMDDLEMIQVIGKGSGGIVQLVRHKWVGTLYALKGIQ 103
Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681
+ ++ + + + + H+ H
Sbjct 104 MN-------------IQEAV----------RKQIVQELKINQATQNAHIVLCHQSFYHNG 140
Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL-ENKNLVHGNVCGRNI 740
+V EY++ G L +++ + + + V+ +Q+ L YL ++++H ++ N+
Sbjct 141 VIYLVLEYMDRGSLADIIKQVKTIL-EPYLAVLCKQVLEGLLYLHHERHVIHRDIKPSNL 199
Query 741 LLARLGLAEGTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSLSTAMD 796
L+ R G +K++D G + R+ V ++APE + G + D
Sbjct 200 LVNRKGE-------VKITDFGVSAVLASSMGQRDTFVGTYNYMAPERISGSSYDY--KSD 250
Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP---------EPSCPQLATLTSQ 847
W G +LE C G P FY+ + + P+ S
Sbjct 251 IWSLGLVILE-CAIGRFPYIPSEGEGWLSFYELLEAIVDQPPPSAPADQFSPEFCAFISS 309
Query 848 CLTYEPTQRPSFRTILRDLT 867
C+ +P +R S +L
Sbjct 310 CIQKDPAERMSASELLNHPF 329
>sp|P47197|AKT2_RAT RAC-beta serine/threonine-protein kinase OS=Rattus
norvegicus OX=10116 GN=Akt2 PE=1 SV=1
Length=481
Score = 210 bits (535), Expect = 1e-57, Method: Composition-based stats.
Identities = 66/273 (24%), Positives = 103/273 (38%), Gaps = 33/273 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960
LG+G FGKV L TG A+K L+ + + E +L+ H +
Sbjct 158 LGKGTFGKVILV----REKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLT 213
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019
K Q L VMEY G L +L R + + +I + YLH+
Sbjct 214 ALKYAF--QTHDRLCFVMEYANGGDLFFHLSRERVFTEDRARFYGAEIVSALEYLHSTDV 271
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
++RD+ N++LD D +KI DFGL+K EG + + APE L++ +
Sbjct 272 VYRDIKLENLMLDKDGHIKITDFGLSK---EGISDGATMKTFCGTPEYLAPEVLEDNDYG 328
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
A D W GV +YE++ Q +L R PR
Sbjct 329 RAVDWWGLGVVMYEMMCGRLPF--------------YNQDHERLFELILMEEIRFPR--T 372
Query 1140 CPCEVYHLMKNCWETEASFR----PT-FENLIP 1167
E L+ + + R P+ + ++
Sbjct 373 LGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVME 405
Score = 167 bits (422), Expect = 9e-43, Method: Composition-based stats.
Identities = 62/308 (20%), Positives = 110/308 (36%), Gaps = 46/308 (15%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
P ++S +M A + R +V + L LG+GT V +R + +
Sbjct 126 SPSDSSTSEMMEVAVSKAR---------AKVTMNDFDYLKLLGKGTFGKVI--LVREKAT 174
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
G K+ ++ ++ + + + ++ H L +
Sbjct 175 GRYYAMKILRKEVIIAKDEVAHTVT-------------------ESRVLQNTRHPFLTAL 215
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHG 733
V EY G L L RER ++ SAL YL + ++V+
Sbjct 216 KYAFQTHDRLCFVMEYANGGDLFFHLSRER-VFTEDRARFYGAEIVSALEYLHSTDVVYR 274
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGAN 789
++ N++L + G IK++D G+ +S + +LAPE L N
Sbjct 275 DIKLENLMLDKDG-------HIKITDFGLSKEGISDGATMKTFCGTPEYLAPEVLED--N 325
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQC 848
A+D WG G + E+ G P ++ + R P P+ +L +
Sbjct 326 DYGRAVDWWGLGVVMYEMMC-GRLPFYNQDHERLFELILMEEIRFPRTLGPEAKSLLAGL 384
Query 849 LTYEPTQR 856
L +P QR
Sbjct 385 LKKDPKQR 392
>sp|P17801|KPRO_MAIZE Putative receptor protein kinase ZmPK1 OS=Zea
mays OX=4577 GN=PK1 PE=2 SV=2
Length=817
Score = 218 bits (555), Expect = 1e-57, Method: Composition-based stats.
Identities = 75/315 (24%), Positives = 118/315 (37%), Gaps = 26/315 (8%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+ + + K K +LG G G V + VAVK
Sbjct 508 WASEKGYKAMTSNFRRYSYRELVKATRKFKVELGRGESGTVYKGVLE-----DDRHVAVK 562
Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990
L + Q + ++ E+ ++ + H ++++ G C + + LV EYV GSL + L
Sbjct 563 KL--ENVRQGKEVFQAELSVIGRINHMNLVRIWGFCSEGSHR--LLVSEYVENGSLANIL 618
Query 991 PRHS----IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFG 1043
+ A + +G+AYLH + IH D+ N+LLD KI DFG
Sbjct 619 FSEGGNILLDWEGRFNIALGVAKGLAYLHHECLEWVIHCDVKPENILLDQAFEPKITDFG 678
Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT------- 1096
L K + G V + + APE + DV+S+GV L ELLT
Sbjct 679 LVKLLNRGGSTQNV-SHVRGTLGYIAPEWVSSLPITAKVDVYSYGVVLLELLTGTRVSEL 737
Query 1097 --HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154
D S K + ++ + L+ P + L +C E
Sbjct 738 VGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDSKLNRPVNYVQARTLIKLAVSCLEE 797
Query 1155 EASFRPTFENLIPIL 1169
+ S RPT E+ + L
Sbjct 798 DRSKRPTMEHAVQTL 812
Score = 190 bits (482), Expect = 2e-48, Method: Composition-based stats.
Identities = 60/301 (20%), Positives = 114/301 (38%), Gaps = 52/301 (17%)
Query 544 CFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603
F L+R P + + T N + S+ + + LG+G V
Sbjct 495 FFVLKRELRP------SELWASEKGYKAMTSNFRRYSYRELVKATRKFKVELGRGESGTV 548
Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663
Y+G L + V +K L + F S++
Sbjct 549 YKGVLEDDRH-------------------------VAVKKL-ENVRQGKEVFQAELSVIG 582
Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASA 721
+++H +L + G C G ++V+EYVE+G L L E G++ + W + +A +A
Sbjct 583 RINHMNLVRIWGFCSEGSHRLLVSEYVENGSLANILFSEGGNILLDWEGRFNIALGVAKG 642
Query 722 LSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGALSREER 772
L+YL ++ ++H +V NILL + K++D G+ G +
Sbjct 643 LAYLHHECLEWVIHCDVKPENILLDQAFEP-------KITDFGLVKLLNRGGSTQNVSHV 695
Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832
+ ++APE + + ++ +D + +G LLE+ E ++ R
Sbjct 696 RGTLGYIAPEWVS--SLPITAKVDVYSYGVVLLELLTGTRVSELVGGTDEVHSMLRKLVR 753
Query 833 L 833
+
Sbjct 754 M 754
>sp|P18654|KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 OS=Mus
musculus OX=10090 GN=Rps6ka3 PE=1 SV=2
Length=740
Score = 216 bits (551), Expect = 1e-57, Method: Composition-based stats.
Identities = 65/279 (23%), Positives = 113/279 (41%), Gaps = 24/279 (9%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHR 941
+ ++ LG+G FGKV L + ++ A+K LK + R
Sbjct 54 HHVKEGHEKADPSQFELLKVLGQGSFGKVFLVK-KISGSDARQLYAMKVLKKATLKVRDR 112
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQL 1000
K E DIL + H I+K Q E L L+++++ G L L + +
Sbjct 113 VRTKMERDILVEVNHPFIVKLHYAF--QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDV 170
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+ ++ + +LH+ I+RDL N+LLD + +K+ DFGL+K E ++ +
Sbjct 171 KFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK---ESIDHEKKAYS 227
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
V + APE + ++D WSFGV ++E+LT Q K + +
Sbjct 228 FCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILK----- 282
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+L P E L++ ++ + R
Sbjct 283 -----------AKLGMPQFLSPEAQSLLRMLFKRNPANR 310
Score = 189 bits (479), Expect = 2e-48, Method: Composition-based stats.
Identities = 68/293 (23%), Positives = 104/293 (35%), Gaps = 29/293 (10%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
+ ++ + D+G G + + TN AVK +
Sbjct 405 HSIVQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATN----MEFAVKIIDKS---- 456
Query 940 HRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GL 997
+ +EI+IL H +II K +D K + +V E + G L D + R
Sbjct 457 -KRDPTEEIEILLRYGQHPNIITLKDVYDDG--KYVYVVTELMKGGELLDKILRQKFFSE 513
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL-LDNDRL---VKIGDFGLAKAVPEGHE 1053
+ I + + YLHAQ +HRDL N+L +D ++I DFG AK + +
Sbjct 514 REASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENG 573
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
+ APE LK + A D+WS GV LY +LT + P E I
Sbjct 574 LLMT---PCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEIL 630
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
G L G D L+ + R T ++
Sbjct 631 ARIGSGKFS-----LSGGYWNSVSDTA----KDLVSKMLHVDPHQRLTAALVL 674
Score = 174 bits (441), Expect = 1e-43, Method: Composition-based stats.
Identities = 61/340 (18%), Positives = 122/340 (36%), Gaps = 41/340 (12%)
Query 526 VRELGAALQGCLLRAGDDCFSLRRCCLPQP--GETSNLIIMRGARASPRTLNLSQLSFHR 583
+ +L Q + + D + + +P E N G+ + + +
Sbjct 3 LAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEGSIKEIAITHHVKEGHEK 62
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
D + L LGQG+ V+ ++ D L +KV
Sbjct 63 ADPSQFELLKVLGQGSFGKVFL----------VKKISGSDARQLY-----------AMKV 101
Query 644 LDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
L + + ++ +V+H + +H + ++ +++ G L L +
Sbjct 102 LKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK 161
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
E K +A +LA AL +L + +++ ++ NILL G IKL+D G
Sbjct 162 EVMFTEEDVKFYLA-ELALALDHLHSLGIIYRDLKPENILLDEEG-------HIKLTDFG 213
Query 762 VGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ ++ E++ + ++APE + + + D W FG + E+ G P Q
Sbjct 214 LSKESIDHEKKAYSFCGTVEYMAPEVV--NRRGHTQSADWWSFGVLMFEML-TGTLPFQG 270
Query 818 RSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQR 856
+ E + +P+ P+ +L P R
Sbjct 271 KDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANR 310
Score = 149 bits (376), Expect = 1e-35, Method: Composition-based stats.
Identities = 53/291 (18%), Positives = 93/291 (32%), Gaps = 26/291 (9%)
Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SHT 668
+G E+ + + + +K++D S D E ++ + H
Sbjct 419 TDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPT----EEIEILLRYGQHP 474
Query 669 HLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK 728
++ + V G +VTE ++ G L + R++ V + + YL +
Sbjct 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKF-FSEREASAVLFTITKTVEYLHAQ 533
Query 729 NLVHGNVCGRNIL-LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL----APEC 783
+VH ++ NIL + G E I++ D G + + + APE
Sbjct 534 GVVHRDLKPSNILYVDESGNPES----IRICDFGFAKQLRAENGLLMTPCYTANFVAPEV 589
Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPL---QSRSPSEKEHFYQRQHR-----LPE 835
L A D W G L + G P +P E
Sbjct 590 LK--RQGYDAACDIWSLGVLLYTML-TGYTPFANGPDDTPEEILARIGSGKFSLSGGYWN 646
Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
L S+ L +P QR + +LR + L D+P
Sbjct 647 SVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPH 697
>sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo
sapiens OX=9606 GN=RPS6KA3 PE=1 SV=1
Length=740
Score = 216 bits (551), Expect = 1e-57, Method: Composition-based stats.
Identities = 65/279 (23%), Positives = 113/279 (41%), Gaps = 24/279 (9%)
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHR 941
+ ++ LG+G FGKV L + ++ A+K LK + R
Sbjct 54 HHVKEGHEKADPSQFELLKVLGQGSFGKVFLVK-KISGSDARQLYAMKVLKKATLKVRDR 112
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQL 1000
K E DIL + H I+K Q E L L+++++ G L L + +
Sbjct 113 VRTKMERDILVEVNHPFIVKLHYAF--QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDV 170
Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
+ ++ + +LH+ I+RDL N+LLD + +K+ DFGL+K E ++ +
Sbjct 171 KFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK---ESIDHEKKAYS 227
Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120
V + APE + ++D WSFGV ++E+LT Q K + +
Sbjct 228 FCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILK----- 282
Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+L P E L++ ++ + R
Sbjct 283 -----------AKLGMPQFLSPEAQSLLRMLFKRNPANR 310
Score = 189 bits (479), Expect = 2e-48, Method: Composition-based stats.
Identities = 68/293 (23%), Positives = 104/293 (35%), Gaps = 29/293 (10%)
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939
+ ++ + D+G G + + TN AVK +
Sbjct 405 HSIVQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATN----MEFAVKIIDKS---- 456
Query 940 HRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GL 997
+ +EI+IL H +II K +D K + +V E + G L D + R
Sbjct 457 -KRDPTEEIEILLRYGQHPNIITLKDVYDDG--KYVYVVTELMKGGELLDKILRQKFFSE 513
Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL-LDNDRL---VKIGDFGLAKAVPEGHE 1053
+ I + + YLHAQ +HRDL N+L +D ++I DFG AK + +
Sbjct 514 REASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENG 573
Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113
+ APE LK + A D+WS GV LY +LT + P E I
Sbjct 574 LLMT---PCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEIL 630
Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
G L G D L+ + R T ++
Sbjct 631 ARIGSGKFS-----LSGGYWNSVSDTA----KDLVSKMLHVDPHQRLTAALVL 674
Score = 173 bits (438), Expect = 3e-43, Method: Composition-based stats.
Identities = 59/341 (17%), Positives = 122/341 (36%), Gaps = 43/341 (13%)
Query 526 VRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNL---IIMRGARASPRTLNLSQLSFH 582
+ +L Q + + D + + +P + + T ++ +
Sbjct 3 LAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH-E 61
Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642
+ D + L LGQG+ V+ ++ D L +K
Sbjct 62 KADPSQFELLKVLGQGSFGKVFL----------VKKISGSDARQLY-----------AMK 100
Query 643 VLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
VL + + ++ +V+H + +H + ++ +++ G L L
Sbjct 101 VLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLS 160
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+E K +A +LA AL +L + +++ ++ NILL G IKL+D
Sbjct 161 KEVMFTEEDVKFYLA-ELALALDHLHSLGIIYRDLKPENILLDEEG-------HIKLTDF 212
Query 761 GVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
G+ ++ E++ + ++APE + + + D W FG + E+ G P Q
Sbjct 213 GLSKESIDHEKKAYSFCGTVEYMAPEVV--NRRGHTQSADWWSFGVLMFEML-TGTLPFQ 269
Query 817 SRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQR 856
+ E + +P+ P+ +L P R
Sbjct 270 GKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANR 310
Score = 149 bits (376), Expect = 1e-35, Method: Composition-based stats.
Identities = 53/291 (18%), Positives = 93/291 (32%), Gaps = 26/291 (9%)
Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SHT 668
+G E+ + + + +K++D S D E ++ + H
Sbjct 419 TDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPT----EEIEILLRYGQHP 474
Query 669 HLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK 728
++ + V G +VTE ++ G L + R++ V + + YL +
Sbjct 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKF-FSEREASAVLFTITKTVEYLHAQ 533
Query 729 NLVHGNVCGRNIL-LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL----APEC 783
+VH ++ NIL + G E I++ D G + + + APE
Sbjct 534 GVVHRDLKPSNILYVDESGNPES----IRICDFGFAKQLRAENGLLMTPCYTANFVAPEV 589
Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPL---QSRSPSEKEHFYQRQHR-----LPE 835
L A D W G L + G P +P E
Sbjct 590 LK--RQGYDAACDIWSLGVLLYTML-TGYTPFANGPDDTPEEILARIGSGKFSLSGGYWN 646
Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886
L S+ L +P QR + +LR + L D+P
Sbjct 647 SVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPH 697
>sp|Q8AXC6|KIT_TAKRU Mast/stem cell growth factor receptor Kit
OS=Takifugu rubripes OX=31033 GN=kit PE=3 SV=1
Length=984
Score = 220 bits (560), Expect = 1e-57, Method: Composition-based stats.
Identities = 92/421 (22%), Positives = 163/421 (39%), Gaps = 95/421 (23%)
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899
+ L L Y+ Q+P ++ + + + +N + F ++ L+
Sbjct 524 CILCLILIVLFYKYMQKPKYQIQWKVIEGIHGNNYVYIDPTQLPYDHQ--WEFPRKNLRF 581
Query 900 IRDLGEGHFGKVSLYC-YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHE 957
+ LG G FGKV Y N+ + VAVK LK+ + E+ +L L H
Sbjct 582 GKTLGSGAFGKVVEATAYGLANEDSMMTVAVKMLKSSAHSTEKEALMSELKVLIYLGNHI 641
Query 958 HIIK----------------------YKGCCEDQGEKSLQLVME----Y--------VPL 983
+I+ + E + +E Y +
Sbjct 642 NIVNLLGACTVGGPTLVITEYCCFGDLLNFLRRKRESFICFKLEEDCHYRNIMLQREMAG 701
Query 984 GSLRDYLPRH----------------------------------------SIGLAQLLLF 1003
SL Y+ S+ LL F
Sbjct 702 DSLNGYMTMRPSAAGKPSSSSSSEKRRSLREGSPYVEEDSESEMFDEDSLSLDTEDLLSF 761
Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063
+ Q+ +GM +L +++ IHRDLAARN+LL R+ KI DFGLA+ + Y V+ +
Sbjct 762 SYQVAKGMEFLTSKNCIHRDLAARNILLTQGRVAKICDFGLARDINTDSNYV-VKGNARL 820
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
PV W +PE + E + + SDVWS+G+ L+E+ + +S G +
Sbjct 821 PVKWMSPESIFECVYTFESDVWSYGILLWEIFSLGNSPY-------------PGMPVDAK 867
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183
+L++ G R+ P+ P E+Y +M++CW+ + RP F ++ + + ++ +
Sbjct 868 FYKLIKEGYRMDAPEFAPSEMYQIMRSCWDADPLNRPPFRKVV---ERIEQQLSDTTKHI 924
Query 1184 F 1184
+
Sbjct 925 Y 925
Score = 150 bits (378), Expect = 2e-35, Method: Composition-based stats.
Identities = 40/221 (18%), Positives = 78/221 (35%), Gaps = 18/221 (8%)
Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748
YVE + + + + Q+A + +L +KN +H ++ RNILL +
Sbjct 736 YVEEDSESEMFDEDSLSLDTEDLLSFSYQVAKGMEFLTSKNCIHRDLAARNILLTQ---- 791
Query 749 EGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGA 802
K+ D G+ + V + + W++PE + + D W +G
Sbjct 792 ---GRVAKICDFGLARDINTDSNYVVKGNARLPVKWMSPESIFECVYTF--ESDVWSYGI 846
Query 803 TLLEICFDGEAPLQSRSPSEK-EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859
L EI G +P K + +R+ PE + ++ + C +P RP F
Sbjct 847 LLWEIFSLGNSPYPGMPVDAKFYKLIKEGYRMDAPEFAPSEMYQIMRSCWDADPLNRPPF 906
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900
R ++ + + + P + +
Sbjct 907 RKVVERIEQQLSDTTKHIYLNFSSRVPVMPRGREESSTHSM 947
Score = 88.2 bits (217), Expect = 3e-16, Method: Composition-based stats.
Identities = 27/136 (20%), Positives = 45/136 (33%), Gaps = 21/136 (15%)
Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632
L +K + LG G V + G E M
Sbjct 563 PTQLPYDHQWEFPRKNLRFGKTLGSGAFGKV----VEATAYGLANEDSM----------- 607
Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690
+ V +K+L S H ++ + +H ++ + G C G +++TEY
Sbjct 608 ----MTVAVKMLKSSAHSTEKEALMSELKVLIYLGNHINIVNLLGACTVGGPTLVITEYC 663
Query 691 EHGPLDVWLRRERGHV 706
G L +LRR+R
Sbjct 664 CFGDLLNFLRRKRESF 679
>sp|Q6Z8C8|CDKF4_ORYSJ Cyclin-dependent kinase F-4 OS=Oryza sativa
subsp. japonica OX=39947 GN=CDKF-4 PE=2 SV=1
Length=459
Score = 209 bits (533), Expect = 1e-57, Method: Composition-based stats.
Identities = 73/291 (25%), Positives = 120/291 (41%), Gaps = 29/291 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
K I+++G+G FG V + N GE+VAVK +K +E+ LR
Sbjct 1 MDRFKMIKEVGDGTFGSV----WRAINKQNGEVVAVKKMKRKYYSFEECMSLREVKSLRR 56
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGM 1011
+ H +I+K K + L +MEY+ +L + A++ + QI + +
Sbjct 57 MNHPNIVKLKEVIREND--ILYFIMEYMEC-NLYQLMKDRVKPFSEAEVRNWCFQIFQAL 113
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
AY+H + Y HRDL N+L+ D ++K+ DFGLA+ V Y + S ++ APE
Sbjct 114 AYMHQRGYFHRDLKPENLLVSKD-VIKLADFGLAREVTSVPPY----TEYVSTRWYRAPE 168
Query 1072 C-LKEYKFYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
L+ + A D+W+ G + ELLT S K +IG Q L+
Sbjct 169 VLLQSSIYDSAVDMWAMGAIMAELLTLHPLFPGTSEADEILKICNVIGSPDEQSWPQGLS 228
Query 1126 ELLERGERLPRPDK---------CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ P+ E L+ + + RP ++
Sbjct 229 LAETMKFQFPQVSGNQLAEVMTSVSSEAVDLISSLCSWDPCKRPKAAEVLQ 279
Score = 162 bits (411), Expect = 2e-41, Method: Composition-based stats.
Identities = 45/265 (17%), Positives = 86/265 (32%), Gaps = 38/265 (14%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ +G GT +V+ + G V +K +
Sbjct 1 MDRFKMIKEVGDGTFGSVWRAINKQNGE------------------------VVAVKKMK 36
Query 646 PSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
++ + +++H ++ + V + EY+E L ++
Sbjct 37 RKYYSFEECMSLREVKSLRRMNHPNIVKLKEVIRENDILYFIMEYMEC-NLYQLMKDRVK 95
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
A Q+ AL+Y+ + H ++ N+L+++ IKL+D G+
Sbjct 96 PFSEAEVRNWCFQIFQALAYMHQRGYFHRDLKPENLLVSKD--------VIKLADFGLAR 147
Query 765 GALS---REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
S E V + APE L ++ +A+D W GA + E+ +
Sbjct 148 EVTSVPPYTEYVSTRWYRAPEVLLQ-SSIYDSAVDMWAMGAIMAELLTLHPLFPGTSEAD 206
Query 822 EKEHFYQRQHRLPEPSCPQLATLTS 846
E E S PQ +L
Sbjct 207 EILKICNVIGSPDEQSWPQGLSLAE 231
>sp|Q5RJI5|BRSK1_MOUSE Serine/threonine-protein kinase BRSK1 OS=Mus
musculus OX=10090 GN=Brsk1 PE=1 SV=1
Length=778
Score = 217 bits (553), Expect = 1e-57, Method: Composition-based stats.
Identities = 72/279 (26%), Positives = 117/279 (42%), Gaps = 29/279 (10%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDI 950
+ + + LG+G G V L + TG+ VAVK + + ++EI I
Sbjct 29 QYVGPYRLEKTLGKGQTGLVKLG----VHCITGQKVAVKIVNREKLSESVLMKVEREIAI 84
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICE 1009
L+ + H H++K E++ K L LV+E+V G L DYL + + + F +QI
Sbjct 85 LKLIEHPHVLKLHDVYENK--KYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVS 142
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ + H+ HRDL N+LLD ++I DFG+A + E +
Sbjct 143 ALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASL----QVGDSLLETSCGSPHYAC 198
Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE +K K+ +D+WS GV L+ LL + +L E +
Sbjct 199 PEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDD---------------NLRQLLEKV 243
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+RG P P + L++ E E R + E +
Sbjct 244 KRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQK 281
Score = 169 bits (427), Expect = 9e-42, Method: Composition-based stats.
Identities = 54/329 (16%), Positives = 101/329 (31%), Gaps = 44/329 (13%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647
LG+G V G + G +V +K+++
Sbjct 35 RLEKTLGKGQTGLVKLGVHCITGQ------------------------KVAVKIVNREKL 70
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
+ + +++ + H H+ +H V +V E+V G L +L ++G +
Sbjct 71 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYL-VKKGRLT 129
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
+Q+ SAL + + ++ H ++ N+LL I+++D G+ +
Sbjct 130 PKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKN-------NIRIADFGMASLQV 182
Query 768 SR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
E + PE + G D W G L + G P + +
Sbjct 183 GDSLLETSCGSPHYACPEVIKGEKYD-GRRADMWSCGVILFALLV-GALPFDDDNLRQLL 240
Query 825 HFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
+R +P P +L + EP +R S I + L + D
Sbjct 241 EKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAP 300
Query 884 SPASDPTVFHKRYLKKIRDLGE----GHF 908
L G F
Sbjct 301 GRRVAMRSLPSNGELDPDVLESMASLGCF 329
>sp|Q10N20|MPK5_ORYSJ Mitogen-activated protein kinase 5 OS=Oryza
sativa subsp. japonica OX=39947 GN=MPK5 PE=1 SV=1
Length=369
Score = 207 bits (526), Expect = 1e-57, Method: Composition-based stats.
Identities = 74/329 (22%), Positives = 116/329 (35%), Gaps = 34/329 (10%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+ + +Y I +G G +G V N T EMVA+
Sbjct 9 FRPTMTHGGRYLLYDIFGNKFEVTNKYQPPIMPIGRGAYGIVCSVM----NFETREMVAI 64
Query 930 KAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGS 985
K + A +EI +LR L HE+II + Q + + E +
Sbjct 65 KKIANAFNNDMDAKRTLREIKLLRHLDHENIIGIRDVIPPPIPQAFNDVYIATELMD-TD 123
Query 986 LRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
L + + F QI G+ Y+H+ + IHRDL N+LL+ + +KI DFGL
Sbjct 124 LHHIIRSNQELSEEHCQYFLYQILRGLKYIHSANVIHRDLKPSNLLLNANCDLKICDFGL 183
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFYYASDVWSFGVTLYELLTHCDSSQ- 1102
A+ E + + ++ APE L + A DVWS G EL+
Sbjct 184 ARPSSESD----MMTEYVVTRWYRAPELLLNSTDYSAAIDVWSVGCIFMELINRQPLFPG 239
Query 1103 ---------------SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
+P L I + + L + R P P + L
Sbjct 240 RDHMHQMRLITEVIGTPTDDELGFIRNEDARKYMRHLPQYPRRTFASMFPRVQPAAL-DL 298
Query 1148 MKNCWETEASFRPTFENLI--PILKTVHE 1174
++ R T E + P L+ +H+
Sbjct 299 IERMLTFNPLQRITVEEALDHPYLERLHD 327
Score = 125 bits (314), Expect = 1e-29, Method: Composition-based stats.
Identities = 33/181 (18%), Positives = 67/181 (37%), Gaps = 22/181 (12%)
Query 639 VVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYV 690
V +K + + D L+ + H ++ + V + + TE +
Sbjct 62 VAIKKIANAFNNDMDAKRT-LREIKLLRHLDHENIIGIRDVIPPPIPQAFNDVYIATELM 120
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
+ L +R + + Q+ L Y+ + N++H ++ N+LL
Sbjct 121 D-TDLHHIIRSNQ-ELSEEHCQYFLYQILRGLKYIHSANVIHRDLKPSNLLLN------- 171
Query 751 TSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+ +K+ D G+ + + E V + APE L + S A+D W G +E+
Sbjct 172 ANCDLKICDFGLARPSSESDMMTEYVVTRWYRAPELLLNSTD-YSAAIDVWSVGCIFMEL 230
Query 808 C 808
Sbjct 231 I 231
>sp|A2XFC8|MPK5_ORYSI Mitogen-activated protein kinase 5 OS=Oryza
sativa subsp. indica OX=39946 GN=MPK5 PE=1 SV=2
Length=369
Score = 207 bits (526), Expect = 1e-57, Method: Composition-based stats.
Identities = 74/329 (22%), Positives = 116/329 (35%), Gaps = 34/329 (10%)
Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929
+ + +Y I +G G +G V N T EMVA+
Sbjct 9 FRPTMTHGGRYLLYDIFGNKFEVTNKYQPPIMPIGRGAYGIVCSVM----NFETREMVAI 64
Query 930 KAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGS 985
K + A +EI +LR L HE+II + Q + + E +
Sbjct 65 KKIANAFNNDMDAKRTLREIKLLRHLDHENIIGIRDVIPPPIPQAFNDVYIATELMD-TD 123
Query 986 LRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044
L + + F QI G+ Y+H+ + IHRDL N+LL+ + +KI DFGL
Sbjct 124 LHHIIRSNQELSEEHCQYFLYQILRGLKYIHSANVIHRDLKPSNLLLNANCDLKICDFGL 183
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFYYASDVWSFGVTLYELLTHCDSSQ- 1102
A+ E + + ++ APE L + A DVWS G EL+
Sbjct 184 ARPSSESD----MMTEYVVTRWYRAPELLLNSTDYSAAIDVWSVGCIFMELINRQPLFPG 239
Query 1103 ---------------SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147
+P L I + + L + R P P + L
Sbjct 240 RDHMHQMRLITEVIGTPTDDELGFIRNEDARKYMRHLPQYPRRTFASMFPRVQPAAL-DL 298
Query 1148 MKNCWETEASFRPTFENLI--PILKTVHE 1174
++ R T E + P L+ +H+
Sbjct 299 IERMLTFNPLQRITVEEALDHPYLERLHD 327
Score = 125 bits (314), Expect = 1e-29, Method: Composition-based stats.
Identities = 33/181 (18%), Positives = 67/181 (37%), Gaps = 22/181 (12%)
Query 639 VVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYV 690
V +K + + D L+ + H ++ + V + + TE +
Sbjct 62 VAIKKIANAFNNDMDAKRT-LREIKLLRHLDHENIIGIRDVIPPPIPQAFNDVYIATELM 120
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
+ L +R + + Q+ L Y+ + N++H ++ N+LL
Sbjct 121 D-TDLHHIIRSNQ-ELSEEHCQYFLYQILRGLKYIHSANVIHRDLKPSNLLLN------- 171
Query 751 TSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+ +K+ D G+ + + E V + APE L + S A+D W G +E+
Sbjct 172 ANCDLKICDFGLARPSSESDMMTEYVVTRWYRAPELLLNSTD-YSAAIDVWSVGCIFMEL 230
Query 808 C 808
Sbjct 231 I 231
>sp|B2DD29|BRSK1_RAT Serine/threonine-protein kinase BRSK1 OS=Rattus
norvegicus OX=10116 GN=Brsk1 PE=1 SV=1
Length=778
Score = 217 bits (553), Expect = 1e-57, Method: Composition-based stats.
Identities = 72/279 (26%), Positives = 117/279 (42%), Gaps = 29/279 (10%)
Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDI 950
+ + + LG+G G V L + TG+ VAVK + + ++EI I
Sbjct 29 QYVGPYRLEKTLGKGQTGLVKLG----VHCITGQKVAVKIVNREKLSESVLMKVEREIAI 84
Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICE 1009
L+ + H H++K E++ K L LV+E+V G L DYL + + + F +QI
Sbjct 85 LKLIEHPHVLKLHDVYENK--KYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVS 142
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ + H+ HRDL N+LLD ++I DFG+A + E +
Sbjct 143 ALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASL----QVGDSLLETSCGSPHYAC 198
Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128
PE +K K+ +D+WS GV L+ LL + +L E +
Sbjct 199 PEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDD---------------NLRQLLEKV 243
Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+RG P P + L++ E E R + E +
Sbjct 244 KRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQK 281
Score = 169 bits (427), Expect = 9e-42, Method: Composition-based stats.
Identities = 54/329 (16%), Positives = 101/329 (31%), Gaps = 44/329 (13%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647
LG+G V G + G +V +K+++
Sbjct 35 RLEKTLGKGQTGLVKLGVHCITGQ------------------------KVAVKIVNREKL 70
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
+ + +++ + H H+ +H V +V E+V G L +L ++G +
Sbjct 71 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYL-VKKGRLT 129
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
+Q+ SAL + + ++ H ++ N+LL I+++D G+ +
Sbjct 130 PKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKN-------NIRIADFGMASLQV 182
Query 768 SR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
E + PE + G D W G L + G P + +
Sbjct 183 GDSLLETSCGSPHYACPEVIKGEKYD-GRRADMWSCGVILFALLV-GALPFDDDNLRQLL 240
Query 825 HFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
+R +P P +L + EP +R S I + L + D
Sbjct 241 EKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAP 300
Query 884 SPASDPTVFHKRYLKKIRDLGE----GHF 908
L G F
Sbjct 301 GRRVAMRSLPSNGELDPDVLESMASLGCF 329
>sp|P13863|CDK1_CHICK Cyclin-dependent kinase 1 OS=Gallus gallus
OX=9031 GN=CDK1 PE=1 SV=1
Length=303
Score = 204 bits (520), Expect = 1e-57, Method: Composition-based stats.
Identities = 63/287 (22%), Positives = 120/287 (42%), Gaps = 29/287 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+
Sbjct 1 MEDYTKIEKIGEGTYGVV----YKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQIC 1008
L+H +I+ + + L L+ E++ + L+ YL + +++ + QI
Sbjct 57 ELHHPNIVCLQDVLMQ--DARLYLIFEFLSM-DLKKYLDTIPSGQYLDRSRVKSYLYQIL 113
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+G+ + H++ +HRDL +N+L+D+ ++K+ DFGLA+A RV +++
Sbjct 114 QGIVFCHSRRVLHRDLKPQNLLIDDKGVIKLADFGLARAFGIP---VRVYTHEVVTLWYR 170
Query 1069 APECLKEYK-FYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQM--- 1119
+PE L + D+WS G EL T H DS + +G +
Sbjct 171 SPEVLLGSALYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNDVWPD 230
Query 1120 -----TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
+ G + L+ + + R +
Sbjct 231 VESLQDYKNTFPKWKPGSLGTHVQNLDEDGLDLLSKMLIYDPAKRIS 277
Score = 162 bits (411), Expect = 5e-43, Method: Composition-based stats.
Identities = 41/267 (15%), Positives = 95/267 (36%), Gaps = 41/267 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ T++ +G+GT VY+GR + G V +K +
Sbjct 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQ------------------------VVAMKKIR 36
Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-- 701
+ + SL+ ++ H ++ + V ++ ++ E++ L +L
Sbjct 37 LESEEEGVPSTAIREISLLKELHHPNIVCLQDVLMQDARLYLIFEFLSM-DLKKYLDTIP 95
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
++ + Q+ + + ++ ++H ++ +N+L+ G+ IKL+D G
Sbjct 96 SGQYLDRSRVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGV-------IKLADFG 148
Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ V + + +PE L G+ ST +D W G E+
Sbjct 149 LARAFGIPVRVYTHEVVTLWYRSPEVLL-GSALYSTPVDIWSIGTIFAELATKKPLFHGD 207
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ P + +L
Sbjct 208 SEIDQLFRIFRALGTPNNDVWPDVESL 234
>sp|P29618|CDKA1_ORYSJ Cyclin-dependent kinase A-1 OS=Oryza sativa
subsp. japonica OX=39947 GN=CDKA-1 PE=1 SV=1
Length=294
Score = 204 bits (519), Expect = 1e-57, Method: Composition-based stats.
Identities = 69/295 (23%), Positives = 123/295 (42%), Gaps = 33/295 (11%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K +GEG +G V Y + T E +A+K ++ + + S +EI +L+
Sbjct 1 MEQYEKEEKIGEGTYGVV----YRARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009
++H +I++ EK + LV EY+ L L+ ++ P + + + QI
Sbjct 57 EMHHGNIVRLHDVI--HSEKRIYLVFEYLDL-DLKKFMDSCPEFAKNPTLIKSYLYQILR 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
G+AY H+ +HRDL +N+L+D +K+ DFGLA+A R +++
Sbjct 114 GVAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIP---VRTFTHEVVTLWYR 170
Query 1069 APECLKE-YKFYYASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIGIAQGQMTVL 1122
APE L ++ D+WS G E++ DS K ++G Q +
Sbjct 171 APEILLGSRQYSTPVDMWSVGCIFAEMVNQKPLFPGDSEIDELFKIFRVLGTPNEQ-SWP 229
Query 1123 RLTELLERGERLPR----------PDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
++ L + P+ P P + L+ E + R T +
Sbjct 230 GVSSLPDYKSAFPKWQAQDLATIVPTLDPAGL-DLLSKMLRYEPNKRITARQALE 283
Score = 159 bits (401), Expect = 8e-42, Method: Composition-based stats.
Identities = 47/266 (18%), Positives = 92/266 (35%), Gaps = 39/266 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
++ + +G+GT VY RD+ + LK
Sbjct 1 MEQYEKEEKIGEGTYGVVYRA------------------------RDKVTNETIALKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702
L+ + SL+ ++ H ++ +H V +V EY++ L ++
Sbjct 37 LEQEDEGVPSTAIREISLLKEMHHGNIVRLHDVIHSEKRIYLVFEYLDL-DLKKFMDSCP 95
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
Q+ ++Y + ++H ++ +N+L+ R A +KL+D G+
Sbjct 96 EFAKNPTLIKSYLYQILRGVAYCHSHRVLHRDLKPQNLLIDRRTNA------LKLADFGL 149
Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + + APE L G+ ST +D W G E+
Sbjct 150 ARAFGIPVRTFTHEVVTLWYRAPEILL-GSRQYSTPVDMWSVGCIFAEMVNQKPLFPGDS 208
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844
E ++ E S P +++L
Sbjct 209 EIDELFKIFRVLGTPNEQSWPGVSSL 234
>sp|A3EZ55|HOG1A_WALI9 Mitogen-activated protein kinase HOG1A
OS=Wallemia ichthyophaga (strain EXF-994 / CBS 113033) OX=1299270
GN=HOG1A PE=1 SV=2
Length=365
Score = 206 bits (525), Expect = 1e-57, Method: Composition-based stats.
Identities = 62/297 (21%), Positives = 112/297 (38%), Gaps = 29/297 (10%)
Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWK 945
++ +G G FG + T+ +G VA+K +K P
Sbjct 14 FGNIFQVTTRYTDLQPVGMGAFGLLC----SSTDQKSGGPVAIKKVMKPFSAPVLAKRTY 69
Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ 1005
+E+ +L+ L HE+II GE + + E + L L + + F
Sbjct 70 RELKLLKHLRHENIISLLDVFISPGED-IYFITELL-GTDLHRLLSSRPLERQFVQYFLY 127
Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
Q+ + ++H +HRDL N+L++ + +KI DFGLA+ Y S
Sbjct 128 QMLRALKFVHPAGVVHRDLKPSNILINENCDLKICDFGLARLQDPQMTGY------VSTR 181
Query 1066 FWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM 1119
++ APE + ++ + A D+WS G E++ T EL+G +
Sbjct 182 YYRAPEIMLTWQEYDSAVDIWSVGCIFAEMIDGRPIFPGKDHVHQLTVITELLGSPPEDV 241
Query 1120 TV-------LRLTELLERGERLPRPDKCP---CEVYHLMKNCWETEASFRPTFENLI 1166
R + L + ++ D+ P E L++ + R T + +
Sbjct 242 INTITSENTRRFVDALPKRHKISFADRFPNANAEEIDLLEKMLDFNPKKRITAADAL 298
Score = 133 bits (335), Expect = 2e-32, Method: Composition-based stats.
Identities = 41/229 (18%), Positives = 78/229 (34%), Gaps = 19/229 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
N+++ R G L D+ V +K V+ P +A Y
Sbjct 14 FGNIFQVTTRYTDLQPVGMGAF---GLLCSSTDQKSGGPVAIKKVMKPFSAPVLAKRTYR 70
Query 658 TASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + V + G + +TE + L L + +
Sbjct 71 ELKLLKHLRHENIISLLDVFISPGEDIYFITELL-GTDLHRLLSSR--PLERQFVQYFLY 127
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-RVER 775
Q+ AL ++ +VH ++ NIL+ + +K+ D G+ + V
Sbjct 128 QMLRALKFVHPAGVVHRDLKPSNILINE-------NCDLKICDFGLARLQDPQMTGYVST 180
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
+ APE + +A+D W G E+ DG + +
Sbjct 181 RYYRAPE-IMLTWQEYDSAVDIWSVGCIFAEMI-DGRPIFPGKDHVHQL 227
>sp|Q17446|PMK1_CAEEL Mitogen-activated protein kinase pmk-1 OS=Caenorhabditis
elegans OX=6239 GN=pmk-1 PE=1 SV=1
Length=377
Score = 207 bits (526), Expect = 1e-57, Method: Composition-based stats.
Identities = 64/327 (20%), Positives = 114/327 (35%), Gaps = 34/327 (10%)
Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922
+ T + + Y + +G G +G V
Sbjct 1 MFPQTTMDHILHPTPREGYYVVELNRSVWVVPNYYINLTPIGTGAYGTVCA----AECTR 56
Query 923 TGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE----KSLQLV 977
+G VA+K + H +E+ +LR + HE+II + + V
Sbjct 57 SGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFV 116
Query 978 MEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037
+ L + L + + QI G+ Y+H+ IHRDL N+ ++ D +
Sbjct 117 SMLM-GADLSNILKIQRLNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCEL 175
Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFYYASDVWSFGVTLYELLT 1096
KI DFGLA+ Y + ++ APE + + + DVWS G L EL+T
Sbjct 176 KILDFGLARQTDSEMTGY------VATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELIT 229
Query 1097 HCDSSQ----------------SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
+P +FL+ I + + + L ++ R +
Sbjct 230 GKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQAT 289
Query 1141 PCEVYHLMKNCWETEASFRPTFENLIP 1167
P + L++ + RPT + +
Sbjct 290 PQAI-DLLEKMLHLDPDRRPTAKEAME 315
Score = 120 bits (302), Expect = 6e-28, Method: Composition-based stats.
Identities = 56/359 (16%), Positives = 97/359 (27%), Gaps = 75/359 (21%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
L+ +G G V G RV +K +
Sbjct 36 INLTPIGTGAYGTVCAAECTRSG------------------------TRVAIKKFNRPFQ 71
Query 650 DI--ALAFYETASLMSQVSHTHLAFVHGVCV------RGPENIMVTEYVEHGPLDVWLRR 701
I A Y L+ + H ++ + V + V+ + L L+
Sbjct 72 SIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLM-GADLSNILKI 130
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
+R + + Q+ L Y+ + +++H ++ NI A +K+ D G
Sbjct 131 QR--LNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNI-------AVNEDCELKILDFG 181
Query 762 VGLGALSREERVERIPWL-APECLPGGANSLSTAMDKWGFGATLLEICF----------- 809
+ S W APE + + +D W G L E+
Sbjct 182 LARQTDSEMTGYVATRWYRAPE-IMLNWMHYTQTVDVWSVGCILAELITGKTLFPGSDHI 240
Query 810 ---------DGEAPLQSRSPSEKEHFYQRQHRLPEPS-----------CPQLATLTSQCL 849
G + E LP+ + PQ L + L
Sbjct 241 DQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQATPQAIDLLEKML 300
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908
+P +RP+ + + H+ D D KKI F
Sbjct 301 HLDPDRRPTAKEAMEHEYLAAYHDETDEPIAEEMDLNDDVRADTIDEWKKIIWEEISDF 359
>sp|Q2U469|MPKC_ASPOR Mitogen-activated protein kinase mpkC OS=Aspergillus
oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=mpkC
PE=3 SV=2
Length=344
Score = 206 bits (523), Expect = 2e-57, Method: Composition-based stats.
Identities = 67/285 (24%), Positives = 107/285 (38%), Gaps = 31/285 (11%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VAVK + +E+ +L+ L HE++
Sbjct 23 QPVGLGAFGLVC----SAYDQITQQHVAVKKMMNPFANASIAKRTYREVKLLKQLRHENL 78
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + LV E + L L + F QI G+ Y+H+
Sbjct 79 IGLCDIFISPLED-IYLVTELL-GTDLGRLLRARPLDNKFAQYFMYQILRGLKYIHSAGV 136
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
IHRDL N+L++ + +KI DFGLA+ Y S ++ APE + ++
Sbjct 137 IHRDLKPSNLLVNENCDLKICDFGLARVQEPQMTGY------VSTRYYRAPEIMLTWQRY 190
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGIAQGQMTVL 1122
D+WS G L E+L +PP + ++ I Q V
Sbjct 191 GKMVDIWSAGCILAEMLRGKPLFPGKDHIHQFFLITEVLGNPPPEVVQKITSGNTQRVVN 250
Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
L R R + +V L++ + R T E +
Sbjct 251 SLPNQEPRPLR-AVFHEFDNDVISLLEQLLLFDPDKRLTAETALQ 294
Score = 139 bits (351), Expect = 1e-34, Method: Composition-based stats.
Identities = 40/243 (16%), Positives = 84/243 (35%), Gaps = 24/243 (10%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDP 646
E + LG T + + + + D+ + V +K +++P
Sbjct 2 EFIRAEILGT-TFET-------TSRYANVQPVGLGAFGLVCSAYDQITQQHVAVKKMMNP 53
Query 647 -SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERG 704
++ IA Y L+ Q+ H +L + + + + +VTE + L LR
Sbjct 54 FANASIAKRTYREVKLLKQLRHENLIGLCDIFISPLEDIYLVTELL-GTDLGRLLRAR-- 110
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + Q+ L Y+ + ++H ++ N+L+ + +K+ D G+
Sbjct 111 PLDNKFAQYFMYQILRGLKYIHSAGVIHRDLKPSNLLVNE-------NCDLKICDFGLAR 163
Query 765 -GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
V + APE + +D W G L E+ G+ + +
Sbjct 164 VQEPQMTGYVSTRYYRAPE-IMLTWQRYGKMVDIWSAGCILAEML-RGKPLFPGKDHIHQ 221
Query 824 EHF 826
Sbjct 222 FFL 224
>sp|Q91820|AURAA_XENLA Aurora kinase A-A OS=Xenopus laevis OX=8355
GN=aurka-a PE=1 SV=1
Length=407
Score = 208 bits (529), Expect = 2e-57, Method: Composition-based stats.
Identities = 59/272 (22%), Positives = 107/272 (39%), Gaps = 30/272 (11%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEI 948
+ + R LG+G FG V L + ++A+K L + ++E+
Sbjct 134 QWCLEDFEIGRPLGKGKFGNVYL----ARERESKFILALKVLFKSQLEKAGVEHQLRREV 189
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQI 1007
+I L H +I++ G D + L+++Y P G L L + + ++ +Q+
Sbjct 190 EIQSHLRHPNILRLYGYFHDAS--RVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQL 247
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
E + Y H++ IHRD+ N+LL ++ +KI DFG + P R + +
Sbjct 248 AEALLYCHSKKVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSR-----RTTLCGTLDY 302
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
PE ++ D+WS GV YE L ++ Q T R++++
Sbjct 303 LPPEMIEGRMHDETVDLWSLGVLCYEFLVGKPPFETD-----------THQETYRRISKV 351
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
P E L+ + + R
Sbjct 352 -----EFQYPPYVSEEARDLVSKLLKHNPNHR 378
Score = 183 bits (464), Expect = 5e-49, Method: Composition-based stats.
Identities = 56/291 (19%), Positives = 108/291 (37%), Gaps = 41/291 (14%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646
++ LG+G NVY R+R + + LKVL
Sbjct 138 EDFEIGRPLGKGKFGNVYLA------------------------RERESKFILALKVLFK 173
Query 647 SHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
S + + + S + H ++ ++G ++ +Y G L L++
Sbjct 174 SQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDASRVYLILDYAPGGELFRELQK-C 232
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ +QLA AL Y +K ++H ++ N+LL G++ +K++D G
Sbjct 233 TRFDDQRSAMYIKQLAEALLYCHSKKVIHRDIKPENLLL-------GSNGELKIADFGWS 285
Query 764 LGALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ A S R + +L PE + G + +D W G E G+ P ++ +
Sbjct 286 VHAPSSRRTTLCGTLDYLPPEMIEGRMH--DETVDLWSLGVLCYEFLV-GKPPFETDTHQ 342
Query 822 EK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
E + + + P + L S+ L + P R + +L ++
Sbjct 343 ETYRRISKVEFQYPPYVSEEARDLVSKLLKHNPNHRLPLKGVLEHPWIIKN 393
>sp|Q0IHQ8|STK10_XENTR Serine/threonine-protein kinase 10 OS=Xenopus
tropicalis OX=8364 GN=stk10 PE=2 SV=1
Length=951
Score = 219 bits (559), Expect = 2e-57, Method: Composition-based stats.
Identities = 77/307 (25%), Positives = 133/307 (43%), Gaps = 32/307 (10%)
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
+ + + + I +LG+G FGKV Y N TG + A K ++ +
Sbjct 21 REYEHVRRDLDPNQVWEIIGELGDGAFGKV----YKAKNKETGILAAAKVIETK-NEEEL 75
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQ 999
+ EI+IL T H I+K G +G+ L +++E+ P G++ + + +
Sbjct 76 EDYMVEIEILATCNHHFIVKLLGSYYWEGK--LWIMIEFCPGGAVDAIMLELDRGLKEPE 133
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
+ +Q+ EG+ YLH+ IHRDL A NVLL D +K+ DFG++ + + + R+
Sbjct 134 IRTICRQMLEGLTYLHSMKMIHRDLKAGNVLLTLDGDIKLADFGVS---AKNVKTLQRRD 190
Query 1060 DGDSPVFWYAPEC-----LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114
+W APE +K+ + Y +D+WS G+TL E+ + L+ I
Sbjct 191 SFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIEMA-QIEPPHHELNPMRVLLKI 249
Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
A+ + L P K E ++ +K + RP+ L+ +
Sbjct 250 AKSEPPT------------LSSPSKWSPEFHNFLKTALDKNPETRPSAAQLLEH--PFVK 295
Query 1175 KYQGQAP 1181
K G P
Sbjct 296 KVSGNKP 302
Score = 176 bits (445), Expect = 2e-43, Method: Composition-based stats.
Identities = 54/350 (15%), Positives = 108/350 (31%), Gaps = 45/350 (13%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
+ LG G VY+ + + G + KV++ +
Sbjct 37 EIIGELGDGAFGKVYKAKNKETG------------------------ILAAAKVIETKNE 72
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
+ + +++ +H + + G + ++ E+ G +D + +
Sbjct 73 EELEDYMVEIEILATCNHHFIVKLLGSYYWEGKLWIMIEFCPGGAVDAIMLELDRGLKEP 132
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LG 765
+ +Q+ L+YL + ++H ++ N+LL IKL+D GV
Sbjct 133 EIRTICRQMLEGLTYLHSMKMIHRDLKAGNVLLT-------LDGDIKLADFGVSAKNVKT 185
Query 766 ALSREERVERIPWLAPECLP---GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
R+ + W+APE + D W G TL+E+ E P +P
Sbjct 186 LQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIEMA-QIEPPHHELNPMR 244
Query 823 KEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTI--LRDLTRLQPHNLAD 876
+ P P+ L P RPS + + ++ +
Sbjct 245 VLLKIAKSEPPTLSSPSKWSPEFHNFLKTALDKNPETRPSAAQLLEHPFVKKVSGNKPLR 304
Query 877 VLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926
L + D + ++ VS + TG+
Sbjct 305 DLVAEAKAEVLDEIEENGEVEEEEASDTPSSNKSVSQSALGEKDKHTGKE 354
>sp|Q38773|CDC2B_ANTMA Cell division control protein 2 homolog
B (Fragment) OS=Antirrhinum majus OX=4151 GN=CDC2B PE=2 SV=1
Length=280
Score = 203 bits (517), Expect = 2e-57, Method: Composition-based stats.
Identities = 70/280 (25%), Positives = 117/280 (42%), Gaps = 29/280 (10%)
Query 907 HFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIKYKGC 965
+G V Y + T E +A+K ++ + + S +EI +L+ ++HE+I+ K
Sbjct 1 AYGVV----YKARDIETNEDIALKKIRLEQEDEGVPSTAIREISLLKEMHHENIVNLKDV 56
Query 966 CEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHR 1022
EK L LV EY+ L L+ ++ P S L + +F QI G+AY H+ +HR
Sbjct 57 VHR--EKRLYLVFEYLDL-DLKKHMDSCPEFSQDLHMVKMFLCQILRGVAYCHSHRVLHR 113
Query 1023 DLAARNVLLD-NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK-FYY 1080
DL +N+L+D +K+ DFGLA+A R +++ APE L + +
Sbjct 114 DLKPQNLLIDRGSNTIKLADFGLARAFGIP---VRTFTHEVVTLWYRAPEVLLGSRHYST 170
Query 1081 ASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
DVWS G E++ DS K +IG + + +
Sbjct 171 PVDVWSVGCIFAEMVNQKPLFPGDSEIDELHKIFRIIGTPNEDIWPGVTSLPDFKSSFPK 230
Query 1136 RPDKCPCEV--------YHLMKNCWETEASFRPTFENLIP 1167
P K + L+ + + S R T + +
Sbjct 231 WPPKELATIVPNLGATGLDLLCKMLQLDPSKRITAKKALE 270
Score = 151 bits (381), Expect = 2e-39, Method: Composition-based stats.
Identities = 42/226 (19%), Positives = 81/226 (36%), Gaps = 15/226 (7%)
Query 626 PLVPGRDRGQELRVVLK--VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683
+ RD + LK L+ + SL+ ++ H ++ + V R
Sbjct 4 VVYKARDIETNEDIALKKIRLEQEDEGVPSTAIREISLLKEMHHENIVNLKDVVHREKRL 63
Query 684 IMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742
+V EY++ L + + + Q+ ++Y + ++H ++ +N+L+
Sbjct 64 YLVFEYLDL-DLKKHMDSCPEFSQDLHMVKMFLCQILRGVAYCHSHRVLHRDLKPQNLLI 122
Query 743 ARLGLAEGTSPFIKLSDPGVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKW 798
R S IKL+D G+ + V + + APE L G+ ST +D W
Sbjct 123 DR------GSNTIKLADFGLARAFGIPVRTFTHEVVTLWYRAPEVLL-GSRHYSTPVDVW 175
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATL 844
G E+ E ++ E P + +L
Sbjct 176 SVGCIFAEMVNQKPLFPGDSEIDELHKIFRIIGTPNEDIWPGVTSL 221
>sp|Q9LSR8|LRK19_ARATH L-type lectin-domain containing receptor
kinase I.9 OS=Arabidopsis thaliana OX=3702 GN=LECRK19 PE=1
SV=2
Length=766
Score = 217 bits (552), Expect = 2e-57, Method: Composition-based stats.
Identities = 74/279 (27%), Positives = 121/279 (43%), Gaps = 22/279 (8%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LG+G FG+V N G +AVK + + G + + E+ +R L H +++
Sbjct 349 FLGKGGFGEVYRG-----NLPQGREIAVKRVSHN-GDEGVKQFVAEVVSMRCLKHRNLVP 402
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA-- 1016
G C + E L LV EY+P GSL ++L + + +Q L+ + I + YLH
Sbjct 403 LFGYCRRKRE--LLLVSEYMPNGSLDEHLFDDQKPVLSWSQRLVVVKGIASALWYLHTGA 460
Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
Q +HRD+ A N++LD + ++GDFG+A+ G V + APE +
Sbjct 461 DQVVLHRDVKASNIMLDAEFHGRLGDFGMARFHEHGGNAATT--AAVGTVGYMAPELI-T 517
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+DV++FGV + E+ C P +E + + + LL+ +
Sbjct 518 MGASTGTDVYAFGVFMLEV--TCGRRPVEPQLQVEKRHMIKWVCECWKKDSLLDATDPRL 575
Query 1136 RPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILKT 1171
EV +MK C RPT E ++ L
Sbjct 576 GGKFVAEEVEMVMKLGLLCSNIVPESRPTMEQVVLYLNK 614
Score = 213 bits (542), Expect = 3e-56, Method: Composition-based stats.
Identities = 68/305 (22%), Positives = 118/305 (39%), Gaps = 63/305 (21%)
Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644
K ++ LG+G VY G L Q + +K +
Sbjct 340 ATKGFSKDEFLGKGGFGEVYRGNL-------------------------PQGREIAVKRV 374
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RER 703
+ + F M + H +L + G C R E ++V+EY+ +G LD L ++
Sbjct 375 SHNGDEGVKQFVAEVVSMRCLKHRNLVPLFGYCRRKRELLLVSEYMPNGSLDEHLFDDQK 434
Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ + ++VV + +ASAL YL ++ ++H +V NI+L +L D
Sbjct 435 PVLSWSQRLVVVKGIASALWYLHTGADQVVLHRDVKASNIMLD-------AEFHGRLGDF 487
Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815
G+ G + V + ++APE + GA ST D + FG +LE+ G P+
Sbjct 488 GMARFHEHGGNAATTAAVGTVGYMAPELITMGA---STGTDVYAFGVFMLEV-TCGRRPV 543
Query 816 QSRSPSEKEHF------YQRQHRLPEPSCPQL------------ATLTSQCLTYEPTQRP 857
+ + EK H ++ L + + P+L L C P RP
Sbjct 544 EPQLQVEKRHMIKWVCECWKKDSLLDATDPRLGGKFVAEEVEMVMKLGLLCSNIVPESRP 603
Query 858 SFRTI 862
+ +
Sbjct 604 TMEQV 608
>sp|Q9FFP9|SRK2H_ARATH Serine/threonine-protein kinase SRK2H OS=Arabidopsis
thaliana OX=3702 GN=SRK2H PE=1 SV=1
Length=360
Score = 206 bits (524), Expect = 2e-57, Method: Composition-based stats.
Identities = 77/290 (27%), Positives = 123/290 (42%), Gaps = 29/290 (10%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
DLG G+FG L + T E+VA+K + + G + +EI R+L H +II+
Sbjct 9 DLGAGNFGVARLL----RHKETKELVAMKYI--ERGRKIDENVAREIINHRSLRHPNIIR 62
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+K L +VMEY G L + + A+ F QQ+ G+ Y H+
Sbjct 63 FKEVILTPTH--LAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQIC 120
Query 1021 HRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
HRDL N LLD L+KI DFG +K + R + +P + APE L ++
Sbjct 121 HRDLKLENTLLDGSPAPLLKICDFGYSK---SSLLHSRPKSTVGTPA-YIAPEVLSRREY 176
Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+DVWS GVTLY +L + P I + ++ + +
Sbjct 177 DGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYV--------- 227
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP---ILKTVHEKYQGQAPSVF 1184
E HL+ + T ++ R T + + LK + ++ A + +
Sbjct 228 -HISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAY 276
Score = 150 bits (379), Expect = 3e-38, Method: Composition-based stats.
Identities = 47/282 (17%), Positives = 88/282 (31%), Gaps = 17/282 (6%)
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690
R + + V +K ++ I + H ++ V + +V EY
Sbjct 22 RHKETKELVAMKYIERG-RKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYA 80
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L + G A QQL + Y + + H ++ N LL
Sbjct 81 SGGELFERI-CNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLD-----GS 134
Query 751 TSPFIKLSDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807
+P +K+ D G +L + V ++APE L D W G TL +
Sbjct 135 PAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYD-GKHADVWSCGVTLYVM 193
Query 808 CFDGEAPLQSRSPSE----KEHFYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRT 861
G P + Q+++P+ + L S+ +R + +
Sbjct 194 LVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKE 253
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903
I + L+ + F + ++ I +
Sbjct 254 IKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKI 295
>sp|F4JBP3|ATG1B_ARATH Serine/threonine-protein kinase ATG1b OS=Arabidopsis
thaliana OX=3702 GN=ATG1B PE=2 SV=1
Length=711
Score = 216 bits (549), Expect = 2e-57, Method: Composition-based stats.
Identities = 72/270 (27%), Positives = 117/270 (43%), Gaps = 33/270 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G F V ++ + G +VA+K + A + + EI ILR + H +II+
Sbjct 26 IGSGSFSVV----WEGRHLVHGTVVAIKEIAMARLNKKLQESLMSEIIILRKINHPNIIR 81
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYI 1020
+ E G+ + LV+EY G L Y+ +H S+ A F Q+ G+ L + I
Sbjct 82 FIDMIEAPGK--INLVLEYCKGGDLSMYIHKHGSVPEATAKHFMLQLAAGLQVLRDNNII 139
Query 1021 HRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
HRDL +N+LL DND +KI DFG A+++ + E + APE ++ K
Sbjct 140 HRDLKPQNLLLSTDDNDAALKIADFGFARSLQPRG----LAETLCGSPLYMAPEIMQLQK 195
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ +D+WS G L++L+T + ++L + + R L P
Sbjct 196 YDAKADLWSVGAILFQLVTGRTPFT---------------GNSQIQLLQNIIRSTELHFP 240
Query 1138 DKC---PCEVYHLMKNCWETEASFRPTFEN 1164
C + L + R TFE
Sbjct 241 ADCRDLSTDCKDLCQKLLRRNPVERLTFEE 270
Score = 186 bits (473), Expect = 9e-48, Method: Composition-based stats.
Identities = 54/326 (17%), Positives = 110/326 (34%), Gaps = 38/326 (12%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ +G G+ + V+EGR V G+ + + + L+
Sbjct 19 DYAVGRQIGSGSFSVVWEGRHLVHGTVVAIK-------------------EIAMARLNK- 58
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
+ + ++ +++H ++ + + +V EY + G L +++ + G VP
Sbjct 59 --KLQESLMSEIIILRKINHPNIIRFIDMIEAPGKINLVLEYCKGGDLSMYIHKH-GSVP 115
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
A QLA+ L L + N++H ++ +N+LL+ + +K++D G
Sbjct 116 EATAKHFMLQLAAGLQVLRDNNIIHRDLKPQNLLLS----TDDNDAALKIADFGFARSLQ 171
Query 768 SR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
R E ++APE + D W GA L ++ G P S +
Sbjct 172 PRGLAETLCGSPLYMAPEIMQ--LQKYDAKADLWSVGAILFQLV-TGRTPFTGNSQIQLL 228
Query 825 HFYQRQHRLP-----EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879
R L L + L P +R +F + +
Sbjct 229 QNIIRSTELHFPADCRDLSTDCKDLCQKLLRRNPVERLTFEEFFHHPFLSDKQSYDFTRS 288
Query 880 VNPDSPASDPTVFHKRYLKKIRDLGE 905
+D + I ++ +
Sbjct 289 RLDSRTMNDFHSSGSSPSRNIEEISQ 314
>sp|P50613|CDK7_HUMAN Cyclin-dependent kinase 7 OS=Homo sapiens
OX=9606 GN=CDK7 PE=1 SV=1
Length=346
Score = 206 bits (523), Expect = 2e-57, Method: Composition-based stats.
Identities = 69/305 (23%), Positives = 121/305 (40%), Gaps = 35/305 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYHE 957
LGEG F V Y + T ++VA+K +K + + G +EI +L+ L H
Sbjct 17 FLGEGQFATV----YKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHP 72
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI--GLAQLLLFAQQICEGMAYLH 1015
+II + ++ LV +++ L + +S+ + + + +G+ YLH
Sbjct 73 NIIGLLDAFGHKS--NISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRDL N+LLD + ++K+ DFGLAK+ + Y + ++ APE L
Sbjct 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQ---VVTRWYRAPELLFG 186
Query 1076 -YKFYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIA--QGQMTVLRLTEL 1127
+ D+W+ G L ELL DS T+ E +G + + L +
Sbjct 187 ARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDY 246
Query 1128 LERGERLPRP-----DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182
+ P ++ L++ + R T + + KY P
Sbjct 247 VTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKM------KYFSNRPG 300
Query 1183 VFSVC 1187
C
Sbjct 301 PTPGC 305
Score = 155 bits (392), Expect = 4e-40, Method: Composition-based stats.
Identities = 46/264 (17%), Positives = 86/264 (33%), Gaps = 42/264 (16%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
+L LG+G VY+ RD+ V +K + H
Sbjct 13 EKLDFLGEGQFATVYKA------------------------RDKNTNQIVAIKKIKLGHR 48
Query 650 DIALA-----FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
A L+ ++SH ++ + +V +++E L+V ++
Sbjct 49 SEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFME-TDLEVIIKDNSL 107
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + L YL ++H ++ N+LL G+ +KL+D G+
Sbjct 108 VLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGV-------LKLADFGLAK 160
Query 765 G----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+ +V + APE L GA +D W G L E+
Sbjct 161 SFGSPNRAYTHQVVTRWYRAPELLF-GARMYGVGVDMWAVGCILAELLLRVPFLPGDSDL 219
Query 821 SEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ E P + +L
Sbjct 220 DQLTRIFETLGTPTEEQWPDMCSL 243
>sp|Q55GS4|CDK10_DICDI Probable cyclin-dependent kinase 10 OS=Dictyostelium
discoideum OX=44689 GN=cdk10 PE=2 SV=1
Length=366
Score = 206 bits (524), Expect = 2e-57, Method: Composition-based stats.
Identities = 71/288 (25%), Positives = 115/288 (40%), Gaps = 32/288 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYHE 957
+GEG +G VS + TG +VA+K +K G Q + G +EI IL+ + H
Sbjct 12 SIGEGTYGIVS----KGRDKETGRIVALKKVK--IGQQDKDGIPLTSLREIQILKEIKHP 65
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLG--SLRDYLPRHSIGLAQLLLFAQQICEGMAYLH 1015
+I+ + LV EY+ SL D + + L+++ F Q+ + YLH
Sbjct 66 NIVSLLEVVIGSTGDKIYLVFEYLEHDVASLIDNINK-PFKLSEIKCFLLQLLRAVEYLH 124
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ IHRDL N+L N+ +K+ DFGLA+ E +++ +PE L
Sbjct 125 SHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPIESI---TPCMVTLWYRSPELLLG 181
Query 1076 -YKFYYASDVWSFGVTLYELLTHCD-----SSQSPPTKFLELIGIAQGQM--TVLRLTEL 1127
K+ A D+WS G ELL + + L+G Q+ L
Sbjct 182 CQKYSTAVDLWSIGSIFGELLIGRPLITGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNF 241
Query 1128 LERGERLPRPDKCPCEV--------YHLMKNCWETEASFRPTFENLIP 1167
+P E+ + L+ + + R T + I
Sbjct 242 KRLNNIPHQPYNNLRELVPTISDTAFDLLNQLLTYDPTKRITASDAIK 289
Score = 163 bits (413), Expect = 1e-42, Method: Composition-based stats.
Identities = 50/265 (19%), Positives = 94/265 (35%), Gaps = 42/265 (16%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648
+L +G+GT V +G RD+ V LK +
Sbjct 7 FEKLDSIGEGTYGIVSKG------------------------RDKETGRIVALKKVKIGQ 42
Query 649 HD---IALAFYETASLMSQVSHTHLAFVHGVCV--RGPENIMVTEYVEHGPLDVWLRRER 703
D I L ++ ++ H ++ + V + G + +V EY+EH + +
Sbjct 43 QDKDGIPLTSLREIQILKEIKHPNIVSLLEVVIGSTGDKIYLVFEYLEH-DVASLIDNIN 101
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
++ QL A+ YL + ++H ++ N+L G + +KL+D G+
Sbjct 102 KPFKLSEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLL-------YGNNGNLKLADFGLA 154
Query 764 LG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
S + + + +PE L G STA+D W G+ E+ +
Sbjct 155 RKFGYPIESITPCMVTLWYRSPELLL-GCQKYSTAVDLWSIGSIFGELLIGRPLITGNNE 213
Query 820 PSEKEHFYQRQHRLPEPSCPQLATL 844
+ + E P ++L
Sbjct 214 VDQIMRIFNLLGEPNEQIWPGFSSL 238
>sp|Q6CJA8|HOG1_KLULA Mitogen-activated protein kinase HOG1 OS=Kluyveromyces
lactis (strain ATCC 8585 / CBS 2359 / DSM 70799
/ NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=HOG1 PE=3
SV=1
Length=444
Score = 209 bits (531), Expect = 2e-57, Method: Composition-based stats.
Identities = 65/318 (20%), Positives = 111/318 (35%), Gaps = 31/318 (10%)
Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KA 934
+ + +G G FG V T+ T + VA+K + K
Sbjct 1 MSNEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVC----SATDTLTSQPVAIKKIMKP 56
Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994
+E+ +L+ L HE++I + E + V E L L
Sbjct 57 FSTSVLAKRTYRELKLLKHLRHENLICLEDIFLSPLED-IYFVTEL-QGTDLHRLLQTRP 114
Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054
+ + F QI G+ Y+H+ IHRDL N+L++ + +KI DFGLA+
Sbjct 115 LEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTG 174
Query 1055 YRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKF 1108
Y S ++ APE + K+ D+WS G E++ +
Sbjct 175 Y------VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSII 228
Query 1109 LELIGIAQGQMTVLRLTELLER-----GERLPRP-----DKCPCEVYHLMKNCWETEASF 1158
+L+G + +E + R P P + L++ +
Sbjct 229 TDLLGSPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKK 288
Query 1159 RPTFENLI--PILKTVHE 1174
R T + + P L H+
Sbjct 289 RITAADALAHPYLSPYHD 306
Score = 137 bits (345), Expect = 4e-33, Method: Composition-based stats.
Identities = 36/213 (17%), Positives = 70/213 (33%), Gaps = 18/213 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
V+E R G + D V +K ++ P +A Y
Sbjct 12 FGTVFEITNRYTNLNPVGMGAF---GLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYR 68
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H +L + + + + VTE + L L+ + +
Sbjct 69 ELKLLKHLRHENLICLEDIFLSPLEDIYFVTEL-QGTDLHRLLQTR--PLEKQFVQYFLY 125
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + ++H ++ NIL+ + +K+ D G+ V
Sbjct 126 QILRGLKYVHSAGVIHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 178
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ APE + + +D W G E+
Sbjct 179 RYYRAPE-IMLTWQKYNVEVDIWSAGCIFAEMI 210
>sp|P32490|MKK1_YEAST MAP kinase kinase MKK1/SSP32 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MKK1
PE=1 SV=1
Length=508
Score = 211 bits (536), Expect = 2e-57, Method: Composition-based stats.
Identities = 67/271 (25%), Positives = 117/271 (43%), Gaps = 19/271 (7%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961
LGEG G VS ++ A+K + + P+++ +E+ R+ E+I++
Sbjct 227 LGEGAGGSVS----KCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVR 282
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLR----DYLPRH-SIGLAQLLLFAQQICEGMAYLHA 1016
Y G D S+ + MEY+ SL + L R I L A+ + G++YLH
Sbjct 283 YYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHE 342
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ IHRD+ +N+LL+ + VK+ DFG++ G + F+ APE ++
Sbjct 343 KKVIHRDIKPQNILLNENGQVKLCDFGVS-----GEAVNSLATTFTGTSFYMAPERIQGQ 397
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+ SDVWS G+T+ E+ P + IA ++ + LT E +
Sbjct 398 PYSVTSDVWSLGLTILEVANGKF----PCSSEKMAANIAPFELLMWILTFTPELKDEPES 453
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ C + ++ RP+ +I
Sbjct 454 NIIWSPSFKSFIDYCLKKDSRERPSPRQMIN 484
Score = 172 bits (437), Expect = 2e-44, Method: Composition-based stats.
Identities = 57/322 (18%), Positives = 104/322 (32%), Gaps = 56/322 (17%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ I L LG+G +V + +L+ LKV++
Sbjct 218 KDRIETLGILGEGAGGSVSKCKLKNGSKIF------------------------ALKVIN 253
Query 646 --PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEHGPLDVW--- 698
+ + + ++ +G+ + EY+ LD
Sbjct 254 TLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKN 313
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
L G + +A+ + LSYL K ++H ++ +NILL G +KL
Sbjct 314 LLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQ-------VKLC 366
Query 759 DPGVGLGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
D GV A++ ++APE + G S D W G T+LE+ +G+ P
Sbjct 367 DFGVSGEAVNSLATTFTGTSFYMAPERIQG--QPYSVTSDVWSLGLTILEVA-NGKFPCS 423
Query 817 ------SRSPSEKEHFY-------QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
+ +P E + + + P + CL + +RPS R ++
Sbjct 424 SEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMI 483
Query 864 RDLTRLQPHNLADVLTVNPDSP 885
+
Sbjct 484 NHPWIKGQMKKNVNMEKFVRKC 505
>sp|Q42438|CDPK8_ARATH Calcium-dependent protein kinase 8 OS=Arabidopsis
thaliana OX=3702 GN=CPK8 PE=1 SV=1
Length=533
Score = 211 bits (538), Expect = 2e-57, Method: Composition-based stats.
Identities = 67/300 (22%), Positives = 111/300 (37%), Gaps = 33/300 (11%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEI 948
R++G G FG L T+ TGE A K++ K ++E+
Sbjct 51 HDISLMYDLGREVGRGEFGITYLC----TDIKTGEKYACKSISKKKLRTAVDIEDVRREV 106
Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006
+I++ + H +I+ K ED + ++ +VME G L D + R +
Sbjct 107 EIMKHMPRHPNIVSLKDAFED--DDAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKT 164
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDS 1063
I E + H +HRDL N L N + +K DFGL+ G + +
Sbjct 165 ILEVVQICHKHGVMHRDLKPENFLFANKKETSALKAIDFGLSVFFKPGEGFNEI----VG 220
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
++ APE L+ + D+WS GV LY LL Q
Sbjct 221 SPYYMAPEVLRRN-YGPEVDIWSAGVILYILLCGVPPF-----------WAETEQGVAQA 268
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183
+ + +R P P L++ E + R + + L+ + +AP+V
Sbjct 269 IIRSVIDFKRDPWPR-VSETAKDLVRKMLEPDPKKRLSAAQV---LEHSWIQNAKKAPNV 324
Score = 135 bits (341), Expect = 5e-32, Method: Composition-based stats.
Identities = 49/327 (15%), Positives = 89/327 (27%), Gaps = 43/327 (13%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQL----SHLGQGTRTNVYEGRLR 609
+P SN + +I+ + +G+G Y
Sbjct 18 KPKIKSNPFYSEAYTTNGSGTGFKLSVLKDPTGHDISLMYDLGREVGRGEFGITY--LCT 75
Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SHT 668
+G+ K + L D +M + H
Sbjct 76 DIKTGEKYACKSISKKKLRTAVD-------------------IEDVRREVEIMKHMPRHP 116
Query 669 HLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK 728
++ + +V E E G L + RGH V + + +
Sbjct 117 NIVSLKDAFEDDDAVHIVMELCEGGELFDRI-VARGHYTERAAAAVMKTILEVVQICHKH 175
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLP 785
++H ++ N L + + +K D G+ + E E V ++APE L
Sbjct 176 GVMHRDLKPENFL----FANKKETSALKAIDFGLSVFFKPGEGFNEIVGSPYYMAPEVLR 231
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-----QHRLPEPSCPQ 840
+ +D W G L I G P + + R +
Sbjct 232 ---RNYGPEVDIWSAGVILY-ILLCGVPPFWAETEQGVAQAIIRSVIDFKRDPWPRVSET 287
Query 841 LATLTSQCLTYEPTQRPSFRTILRDLT 867
L + L +P +R S +L
Sbjct 288 AKDLVRKMLEPDPKKRLSAAQVLEHSW 314
>sp|Q9WVC6|SGK1_MOUSE Serine/threonine-protein kinase Sgk1 OS=Mus
musculus OX=10090 GN=Sgk1 PE=1 SV=1
Length=431
Score = 208 bits (530), Expect = 2e-57, Method: Composition-based stats.
Identities = 66/338 (20%), Positives = 117/338 (35%), Gaps = 29/338 (9%)
Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885
F +++ ++A+ T C E + + +
Sbjct 27 FMKQRRMGLNDFIQKIASNTYACKHAEVQSILKMSHPQEPELMNANPSPPPSPSQQINLG 86
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSG 943
S ++ +G+G FGKV L + AVK L KA +
Sbjct 87 PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEV----FYAVKVLQKKAILKKKEEKH 142
Query 944 WKQEID-ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLL 1001
E + +L+ + H ++ Q L V++Y+ G L +L R +
Sbjct 143 IMSERNVLLKNVKHPFLVGLH--FSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRAR 200
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
+A +I + YLH+ + ++RDL N+LLD+ + + DFGL K E E+
Sbjct 201 FYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCK---ENIEHNGTTSTF 257
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
+ APE L + + D W G LYE+L + T
Sbjct 258 CGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPF--------------YSRNTA 303
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+L + +L HL++ + + + R
Sbjct 304 EMYDNILNKPLQLK--PNITNSARHLLEGLLQKDRTKR 339
Score = 162 bits (411), Expect = 1e-41, Method: Composition-based stats.
Identities = 68/313 (22%), Positives = 110/313 (35%), Gaps = 45/313 (14%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612
PQ E N + + +NL S + L +G+G+ V
Sbjct 63 PQEPELMN-ANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKV--------- 112
Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETAS-LMSQVSHT 668
+ R + +E+ +KVL + L+ V H
Sbjct 113 ---------------LLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 157
Query 669 HLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK 728
L +H + V +Y+ G L L+RER + + A ++ASAL YL +
Sbjct 158 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARF-YAAEIASALGYLHSL 216
Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREERVERIPWLAPECL 784
N+V+ ++ NILL G I L+D G+ + + +LAPE L
Sbjct 217 NIVYRDLKPENILLDSQG-------HIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVL 269
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPSCPQLAT 843
+D W GA L E+ G P SR+ +E + + +L
Sbjct 270 H--KQPYDRTVDWWCLGAVLYEML-YGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARH 326
Query 844 LTSQCLTYEPTQR 856
L L + T+R
Sbjct 327 LLEGLLQKDRTKR 339
>sp|P25323|MYLKA_DICDI Myosin light chain kinase A OS=Dictyostelium
discoideum OX=44689 GN=mlkA PE=1 SV=2
Length=295
Score = 204 bits (518), Expect = 2e-57, Method: Composition-based stats.
Identities = 74/291 (25%), Positives = 111/291 (38%), Gaps = 33/291 (11%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEI 948
++ + +LG G F V L N T + A+K + K++ G + K E+
Sbjct 1 MTEVEKIYEFKEELGRGAFSIVYLG----ENKQTKQRYAIKVINKSELGKDYEKNLKMEV 56
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQI 1007
DIL+ + H +II K + L LVME V G L D + + S A ++I
Sbjct 57 DILKKVNHPNIIALKELF--DTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKI 114
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064
+ YLH + +HRDL N+LL N V I DFGL+K + + V +
Sbjct 115 VSAVGYLHGLNIVHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQ----TLVMQTACGT 170
Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124
+ APE L + D+WS GV Y LL G
Sbjct 171 PSYVAPEVLNATGYDKEVDMWSIGVITYILLCGFPPF--------------YGDTVPEIF 216
Query 1125 TELLERGERLP--RPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKT 1171
+++E P E + + S R N + P LK+
Sbjct 217 EQIMEANYEFPEEYWGGISKEAKDFIGKLLVVDVSKRLNATNALNHPWLKS 267
Score = 160 bits (406), Expect = 2e-42, Method: Composition-based stats.
Identities = 49/255 (19%), Positives = 90/255 (35%), Gaps = 38/255 (15%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647
LG+G + VY G ++ + R +KV++ S
Sbjct 9 EFKEELGRGAFSIVYLG------------------------ENKQTKQRYAIKVINKSEL 44
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
D ++ +V+H ++ + + + +V E V G L + E+G
Sbjct 45 GKDYEKNLKMEVDILKKVNHPNIIALKELFDTPEKLYLVMELVTGGELFDKI-VEKGSYS 103
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--- 764
A + +++ SA+ YL N+VH ++ N+LL + + ++D G+
Sbjct 104 EADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKS----KENHLEVAIADFGLSKIIG 159
Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK- 823
L + ++APE L A +D W G I G P + E
Sbjct 160 QTLVMQTACGTPSYVAPEVL--NATGYDKEVDMWSIGVITY-ILLCGFPPFYGDTVPEIF 216
Query 824 EHFYQRQHRLPEPSC 838
E + + PE
Sbjct 217 EQIMEANYEFPEEYW 231
>sp|Q7SY52|STK10_DANRE Serine/threonine-protein kinase 10 OS=Danio
rerio OX=7955 GN=stk10 PE=2 SV=1
Length=974
Score = 219 bits (558), Expect = 2e-57, Method: Composition-based stats.
Identities = 75/306 (25%), Positives = 130/306 (42%), Gaps = 30/306 (10%)
Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
+ ++ V + I +LG+G FGKV Y N TG + A
Sbjct 9 MFRLPTIEIKKKTKQYNHLQRDVNPNDMWEIIGELGDGAFGKV----YKAQNKETGVLAA 64
Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
K ++ + + EIDIL + H++I+K + S+ + E+ P G++
Sbjct 65 AKVIETK-SEEELEDYMVEIDILASCNHQYIVKLLDAFFFDNKLSIMI--EFCPGGAVDA 121
Query 989 YLPR--HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046
+ + Q+ + +Q+ E + YLH+ IHRDL A N+LL D +K+ DFG++
Sbjct 122 IMLELDRGLQEPQIRVICKQMLEALQYLHSMKIIHRDLKAGNILLTLDGDIKLADFGVS- 180
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPEC-----LKEYKFYYASDVWSFGVTLYELLTHCDSS 1101
+ + + R+ +W APE +K+ + Y +D+WS G+TL EL +
Sbjct 181 --AKNTKTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIEL-----AQ 233
Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161
PP L +L++ + G L +P K + +K + RPT
Sbjct 234 IEPPHHEL------NPMRVLLKIAKSEPPG--LDQPSKWSMDFNDFLKKALDRHPETRPT 285
Query 1162 FENLIP 1167
L+
Sbjct 286 AAQLLE 291
Score = 177 bits (450), Expect = 5e-44, Method: Composition-based stats.
Identities = 54/311 (17%), Positives = 99/311 (32%), Gaps = 45/311 (14%)
Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
+ + N Q + D EI LG G VY+ + + G
Sbjct 18 KKKTKQYNHLQRDVNPNDMWEII--GELGDGAFGKVYKAQNKETG--------------- 60
Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687
+ KV++ + + +++ +H ++ + + ++
Sbjct 61 ---------VLAAAKVIETKSEEELEDYMVEIDILASCNHQYIVKLLDAFFFDNKLSIMI 111
Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747
E+ G +D + + V+ +Q+ AL YL + ++H ++ NILL
Sbjct 112 EFCPGGAVDAIMLELDRGLQEPQIRVICKQMLEALQYLHSMKIIHRDLKAGNILLT---- 167
Query 748 AEGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLP---GGANSLSTAMDKWGF 800
IKL+D GV R+ + W+APE + D W
Sbjct 168 ---LDGDIKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSL 224
Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQR----QHRLPEPSCPQLATLTSQCLTYEPTQR 856
G TL+E+ E P +P + P + L P R
Sbjct 225 GITLIELA-QIEPPHHELNPMRVLLKIAKSEPPGLDQPSKWSMDFNDFLKKALDRHPETR 283
Query 857 PSFRTILRDLT 867
P+ +L
Sbjct 284 PTAAQLLEHPF 294
>sp|Q38873|CDPK7_ARATH Calcium-dependent protein kinase 7 OS=Arabidopsis
thaliana OX=3702 GN=CPK7 PE=2 SV=1
Length=535
Score = 211 bits (538), Expect = 2e-57, Method: Composition-based stats.
Identities = 69/300 (23%), Positives = 112/300 (37%), Gaps = 33/300 (11%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEI 948
R++G G FG L T+ TGE A K++ K ++E+
Sbjct 53 HDISLQYDLGREVGRGEFGITYLC----TDKETGEKYACKSISKKKLRTAVDIEDVRREV 108
Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006
+I++ + H +++ K ED + ++ +VME G L D + R +
Sbjct 109 EIMKHMPKHPNVVSLKDSFED--DDAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKT 166
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDS 1063
I E + H Q +HRDL N L N + +K DFGL+ G ++ +
Sbjct 167 IVEVVQICHKQGVMHRDLKPENFLFANKKETSALKAIDFGLSVFFKPGEQFNEI----VG 222
Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123
++ APE L+ + DVWS GV LY LL Q
Sbjct 223 SPYYMAPEVLRRN-YGPEIDVWSAGVILYILLCGVPPF-----------WAETEQGVAQA 270
Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183
+ + +R P P L++ E + R T + L+ +AP+V
Sbjct 271 IIRSVIDFKRDPWPR-VSDSAKDLVRKMLEPDPKKRLTAAQV---LEHTWILNAKKAPNV 326
Score = 135 bits (340), Expect = 7e-32, Method: Composition-based stats.
Identities = 50/331 (15%), Positives = 95/331 (29%), Gaps = 44/331 (13%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK-----EITQLSHLGQGTRTNVYEGRL 608
+P +N + R+ +LS + + +G+G Y
Sbjct 19 KPKNKNNPFYSNEYATTDRSGAGFKLSVLKDPTGHDISLQYDLGREVGRGEFGITY--LC 76
Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SH 667
+ +G+ K + L D +M + H
Sbjct 77 TDKETGEKYACKSISKKKLRTAVD-------------------IEDVRREVEIMKHMPKH 117
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
++ + +V E E G L + RGH V + + +
Sbjct 118 PNVVSLKDSFEDDDAVHIVMELCEGGELFDRI-VARGHYTERAAAAVMKTIVEVVQICHK 176
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECL 784
+ ++H ++ N L + + +K D G+ + E E V ++APE L
Sbjct 177 QGVMHRDLKPENFL----FANKKETSALKAIDFGLSVFFKPGEQFNEIVGSPYYMAPEVL 232
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-----QHRLPEPSCP 839
+ +D W G L I G P + + R +
Sbjct 233 R---RNYGPEIDVWSAGVILY-ILLCGVPPFWAETEQGVAQAIIRSVIDFKRDPWPRVSD 288
Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
L + L +P +R + +L L
Sbjct 289 SAKDLVRKMLEPDPKKRLTAAQVLEHTWILN 319
>sp|F4KA50|LRL22_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE
PROTEIN KINASE-like 2.2 OS=Arabidopsis thaliana
OX=3702 GN=LRK10L-2.2 PE=3 SV=2
Length=624
Score = 213 bits (543), Expect = 2e-57, Method: Composition-based stats.
Identities = 64/278 (23%), Positives = 114/278 (41%), Gaps = 25/278 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+G G FG V N G VAVK LK G + + E+ + H +I+
Sbjct 323 VGRGGFGTVYKG-----NLRDGRKVAVKILKDSNG--NCEDFINEVASISQTSHVNIVSL 375
Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH---AQHY 1019
G C ++ +++ +V E++ GSL ++ ++ L A + G+ YLH +
Sbjct 376 LGFCFEKSKRA--IVYEFLENGSLD---QSSNLDVSTLYGIALGVARGIEYLHFGCKKRI 430
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE--YK 1077
+H D+ +NVLLD + K+ DFGLAK E E D + + APE
Sbjct 431 VHFDIKPQNVLLDENLKPKVADFGLAKLC-EKQESILSLLDTRGTIGYIAPELFSRVYGN 489
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE-----LIGIAQGQMTVLRLTELLERGE 1132
+ SDV+S+G+ + E+ T + + + +LL G
Sbjct 490 VSHKSDVYSYGMLVLEM-TGARNKERVQNADSNNSSAYFPDWIFKDLENGDYVKLLADGL 548
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ ++ + C + S RP+ ++ +++
Sbjct 549 TREE-EDIAKKMILVGLWCIQFRPSDRPSMNKVVGMME 585
Score = 199 bits (506), Expect = 2e-52, Method: Composition-based stats.
Identities = 58/344 (17%), Positives = 121/344 (35%), Gaps = 66/344 (19%)
Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633
+ + S+ ++ + + +G+G VY+G LR
Sbjct 302 VTSRRYSYRQIKKITKSFTEVVGRGGFGTVYKGNLRDGR--------------------- 340
Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693
+V +K+L S+ + F + +SQ SH ++ + G C + +V E++E+G
Sbjct 341 ----KVAVKILKDSNGNC-EDFINEVASISQTSHVNIVSLLGFCFEKSKRAIVYEFLENG 395
Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEG 750
LD ++ ++ +A +A + YL K +VH ++ +N+LL
Sbjct 396 SLDQ-----SSNLDVSTLYGIALGVARGIEYLHFGCKKRIVHFDIKPQNVLLDE------ 444
Query 751 TSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804
+ K++D G+ LS + I ++APE ++S D + +G +
Sbjct 445 -NLKPKVADFGLAKLCEKQESILSLLDTRGTIGYIAPELFSRVYGNVSHKSDVYSYGMLV 503
Query 805 LEIC---------------FDGEAPLQSRSPSE----KEHFYQRQHRLPEPSCPQLATLT 845
LE+ P E + R E ++ +
Sbjct 504 LEMTGARNKERVQNADSNNSSAYFPDWIFKDLENGDYVKLLADGLTREEEDIAKKMILVG 563
Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889
C+ + P+ RPS ++ + + ++
Sbjct 564 LWCIQFRPSDRPSMNKVVGMMEGNLDSLDPPPKPLLHMPMQNNN 607
>sp|Q6FIU2|HOG1_CANGA Mitogen-activated protein kinase HOG1 OS=Candida
glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761
/ NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=HOG1 PE=3 SV=1
Length=447
Score = 209 bits (531), Expect = 2e-57, Method: Composition-based stats.
Identities = 61/283 (22%), Positives = 105/283 (37%), Gaps = 29/283 (10%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+G G FG V T+ T + VA+K + K +E+ +L+ L HE++
Sbjct 27 NPVGMGAFGLVC----SATDTLTNQQVAIKKIMKPFATAVLAKRTYRELKLLKHLRHENL 82
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I + E + V E L L + + F QI G+ Y+H+
Sbjct 83 ICLQDIFLSPLED-IYFVTEL-QGTDLHRLLQTRPLEKQFVQYFHYQILRGLKYVHSAGV 140
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 141 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 194
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTVLRLTELLER--- 1130
D+WS G E++ + +L+G + +E +
Sbjct 195 DVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPSDVIDTICSENTLKFVT 254
Query 1131 --GERLPRP-----DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
R P P + L++ + R T + +
Sbjct 255 SLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADAL 297
Score = 134 bits (337), Expect = 5e-32, Method: Composition-based stats.
Identities = 46/267 (17%), Positives = 85/267 (32%), Gaps = 21/267 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
V+E R G + D +V +K ++ P +A Y
Sbjct 13 FGTVFEITNRYSDLNPVGMGAF---GLVCSATDTLTNQQVAIKKIMKPFATAVLAKRTYR 69
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H +L + + + + VTE + L L+ + +
Sbjct 70 ELKLLKHLRHENLICLQDIFLSPLEDIYFVTEL-QGTDLHRLLQTR--PLEKQFVQYFHY 126
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 127 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 179
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
+ APE + +D W G E+ +G+ + F L
Sbjct 180 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEMI-EGKPLFPGKDH--VHQFSIITDLLGS 235
Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTI 862
P + T+ S+ T P I
Sbjct 236 PPSDVIDTICSENTLKFVTSLPHRDPI 262
>sp|Q60823|AKT2_MOUSE RAC-beta serine/threonine-protein kinase
OS=Mus musculus OX=10090 GN=Akt2 PE=1 SV=1
Length=481
Score = 210 bits (534), Expect = 2e-57, Method: Composition-based stats.
Identities = 77/390 (20%), Positives = 128/390 (33%), Gaps = 61/390 (16%)
Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQC--LTYEPTQRPSFRTILRDLTRL 869
EAP Q+ P +F + +L + P+ T +C T + + +
Sbjct 43 EAPDQTLPP--LNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWM 100
Query 870 QPHNLADVLTVNPDSPASDPTVFH------------------------KRYLKKIRDLGE 905
+ + ++ LG+
Sbjct 101 RAIQMVANSLKQRGPGEDAMDYKCGSPSDSSTSEMMEVAVNKARAKVTMNDFDYLKLLGK 160
Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYK 963
G FGKV L TG A+K L+ + + E +L+ H + K
Sbjct 161 GTFGKVILV----REKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALK 216
Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHR 1022
Q L VMEY G L +L R + + +I + YLH++ ++R
Sbjct 217 YAF--QTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRDVVYR 274
Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082
D+ N++LD D +KI DFGL K EG + + APE L++ + A
Sbjct 275 DIKLENLMLDKDGHIKITDFGLCK---EGISDGATMKTFCGTPEYLAPEVLEDNDYGRAV 331
Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142
D W GV +YE++ Q +L R PR
Sbjct 332 DWWGLGVVMYEMMCGRLPF--------------YNQDHERLFELILMEEIRFPR--TLGP 375
Query 1143 EVYHLMKNCWETEASFR----PT-FENLIP 1167
E L+ + + R P+ + ++
Sbjct 376 EAKSLLAGLLKKDPKQRLGGGPSDAKEVME 405
Score = 165 bits (418), Expect = 3e-42, Method: Composition-based stats.
Identities = 62/308 (20%), Positives = 110/308 (36%), Gaps = 46/308 (15%)
Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613
P ++S +M A R +V + L LG+GT V +R + +
Sbjct 126 SPSDSSTSEMMEVAVNKAR---------AKVTMNDFDYLKLLGKGTFGKVI--LVREKAT 174
Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673
G K+ ++ ++ + + + ++ H L +
Sbjct 175 GRYYAMKILRKEVIIAKDEVAHTVT-------------------ESRVLQNTRHPFLTAL 215
Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHG 733
V EY G L L RER ++ SAL YL ++++V+
Sbjct 216 KYAFQTHDRLCFVMEYANGGELFFHLSRER-VFTEDRARFYGAEIVSALEYLHSRDVVYR 274
Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGAN 789
++ N++L + G IK++D G+ +S + +LAPE L N
Sbjct 275 DIKLENLMLDKDG-------HIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLED--N 325
Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQC 848
A+D WG G + E+ G P ++ + R P P+ +L +
Sbjct 326 DYGRAVDWWGLGVVMYEMMC-GRLPFYNQDHERLFELILMEEIRFPRTLGPEAKSLLAGL 384
Query 849 LTYEPTQR 856
L +P QR
Sbjct 385 LKKDPKQR 392
>sp|Q9C9M7|CDKD2_ARATH Cyclin-dependent kinase D-2 OS=Arabidopsis
thaliana OX=3702 GN=CDKD-2 PE=1 SV=1
Length=348
Score = 205 bits (522), Expect = 2e-57, Method: Composition-based stats.
Identities = 69/298 (23%), Positives = 123/298 (41%), Gaps = 36/298 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-GWKQEIDILRTLYHEHIIK 961
LGEG +G V Y T+ TG+ VAVK ++ + + +EI +L+ L H HI++
Sbjct 19 LGEGTYGVV----YKATDTKTGKTVAVKKIRLGNQKEGVNFTALREIKLLKELNHPHIVE 74
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019
G SL LV EY+ L + +I L+ + + +G+AY H +
Sbjct 75 LIDAFPHDG--SLHLVFEYMQ-TDLEAVIRDRNIFLSPGDIKSYMLMTLKGLAYCHKKWV 131
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRD+ N+L+ + L+K+ DFGLA+ + + + ++ APE L ++
Sbjct 132 LHRDMKPNNLLIGENGLLKLADFGLARLFGSPNRRFTHQVFA---TWYRAPELLFGSRQY 188
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG---------IAQGQMTVLRLTELLE 1129
DVW+ G ELL P + ++ +G + ++ L + +E
Sbjct 189 GAGVDVWAAGCIFAELLLRRPFL--PGSTEIDQLGKIFQAFGTPVPSQWSDMIYLPDYME 246
Query 1130 RGERLPRP-----DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182
P + L+ + + R T + + +Y +PS
Sbjct 247 FSYTPAPPLRTIFPMASDDALDLLAKMFIYDPRQRITIQQ------ALDHRYFSSSPS 298
Score = 150 bits (380), Expect = 2e-38, Method: Composition-based stats.
Identities = 45/255 (18%), Positives = 81/255 (32%), Gaps = 40/255 (16%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654
LG+GT VY+ D V +K + + +
Sbjct 19 LGEGTYGVVYKA------------------------TDTKTGKTVAVKKIRLGNQKEGVN 54
Query 655 F--YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
F L+ +++H H+ + +V EY++ L+ +R +
Sbjct 55 FTALREIKLLKELNHPHIVELIDAFPHDGSLHLVFEYMQ-TDLEAVIRDRNIFLSPGDIK 113
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772
L+Y K ++H ++ N+L+ GL +KL+D G+ S R
Sbjct 114 SYMLMTLKGLAYCHKKWVLHRDMKPNNLLIGENGL-------LKLADFGLARLFGSPNRR 166
Query 773 ----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA-PLQSRSPSEKEHFY 827
V + APE L G+ +D W G E+ P + + F
Sbjct 167 FTHQVFATWYRAPELLF-GSRQYGAGVDVWAAGCIFAELLLRRPFLPGSTEIDQLGKIFQ 225
Query 828 QRQHRLPEPSCPQLA 842
+P +
Sbjct 226 AFGTPVPSQWSDMIY 240
>sp|Q9WUT3|KS6A2_MOUSE Ribosomal protein S6 kinase alpha-2 OS=Mus
musculus OX=10090 GN=Rps6ka2 PE=1 SV=1
Length=733
Score = 216 bits (549), Expect = 2e-57, Method: Composition-based stats.
Identities = 68/259 (26%), Positives = 109/259 (42%), Gaps = 24/259 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961
LG+G +GKV L T G++ A+K LK + R K E DIL + H I+K
Sbjct 65 LGQGSYGKVFLVR-KVTGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVK 123
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020
Q E L L+++++ G L L + + + ++ + +LH I
Sbjct 124 LHYAF--QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHGLGII 181
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
+RDL N+LLD + +KI DFGL+K E ++ + + + APE +
Sbjct 182 YRDLKPENILLDEEGHIKITDFGLSK---EATDHDKRAYSFCGTIEYMAPEVVNRRGHTQ 238
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
++D WSFGV ++E+LT Q K T L +L P
Sbjct 239 SADWWSFGVLMFEMLTGSLPFQGKDRKE----------------TMALILKAKLGMPQFL 282
Query 1141 PCEVYHLMKNCWETEASFR 1159
E L++ ++ R
Sbjct 283 SAEAQSLLRALFKRNPCNR 301
Score = 198 bits (504), Expect = 1e-51, Method: Composition-based stats.
Identities = 65/307 (21%), Positives = 104/307 (34%), Gaps = 37/307 (12%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
++ + + D+G G + + T+ AVK
Sbjct 389 QQDVPKAPIHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATD----AEYAVK 444
Query 931 ALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD- 988
+ + +EI+IL H +II K +D K + LVME + G L D
Sbjct 445 IIDKS-----KRDPSEEIEILLRYGQHPNIITLKDVYDDG--KYVYLVMELMRGGELLDR 497
Query 989 YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL-LDNDRL---VKIGDFGL 1044
L + + I M YLH+Q +HRDL N+L +D ++I DFG
Sbjct 498 ILRQRCFSEREASDVLYTIARTMDYLHSQGVVHRDLKPSNILYMDESGNPESIRICDFGF 557
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS--- 1101
AK + + + APE LK + A DVWS G+ LY +L
Sbjct 558 AKQLRAENGLLMT---PCYTANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANG 614
Query 1102 -QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
P + L IG + ++ D ++ + R
Sbjct 615 PDDTPEEILARIGSGKYALSGGNW-------------DSISDAAKDVVSKMLHVDPQQRL 661
Query 1161 TFENLIP 1167
T ++
Sbjct 662 TAVQVLK 668
Score = 174 bits (440), Expect = 2e-43, Method: Composition-based stats.
Identities = 59/283 (21%), Positives = 106/283 (37%), Gaps = 39/283 (14%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
F + D + L LGQG+ V+ R V G D GQ
Sbjct 51 FEKADPSQFELLKVLGQGSYGKVFLVR-------------------KVTGSDAGQ--LYA 89
Query 641 LKVLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+KVL + + ++++V+H + +H + ++ +++ G L
Sbjct 90 MKVLKKATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTR 149
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
L +E K +A +LA AL +L +++ ++ NILL G IK++
Sbjct 150 LSKEVMFTEEDVKFYLA-ELALALDHLHGLGIIYRDLKPENILLDEEG-------HIKIT 201
Query 759 DPGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
D G+ A ++R I ++APE + + + D W FG + E+ G P
Sbjct 202 DFGLSKEATDHDKRAYSFCGTIEYMAPEVV--NRRGHTQSADWWSFGVLMFEML-TGSLP 258
Query 815 LQSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQR 856
Q + E + +P+ + +L P R
Sbjct 259 FQGKDRKETMALILKAKLGMPQFLSAEAQSLLRALFKRNPCNR 301
Score = 155 bits (392), Expect = 1e-37, Method: Composition-based stats.
Identities = 48/267 (18%), Positives = 87/267 (33%), Gaps = 24/267 (9%)
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690
+ + +K++D S D + E ++ + H ++ + V G +V E +
Sbjct 434 HKATDAEYAVKIIDKSKRDPS----EEIEILLRYGQHPNIITLKDVYDDGKYVYLVMELM 489
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L + R+R V +A + YL ++ +VH ++ NIL G
Sbjct 490 RGGELLDRILRQRC-FSEREASDVLYTIARTMDYLHSQGVVHRDLKPSNIL---YMDESG 545
Query 751 TSPFIKLSDPGVGLGALSREERVERIPWL----APECLPGGANSLSTAMDKWGFGATLLE 806
I++ D G + + + APE L A D W G L
Sbjct 546 NPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK--RQGYDAACDVWSLGILLYT 603
Query 807 ICFDGEAPL---QSRSPSEKEHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPS 858
+ G P +P E + + S+ L +P QR +
Sbjct 604 MLA-GFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPQQRLT 662
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSP 885
+L+ + L+ D
Sbjct 663 AVQVLKHPWIVNREYLSQNQLSRQDVH 689
>sp|Q05006|CDC22_MEDSA Cell division control protein 2 homolog
2 OS=Medicago sativa OX=3879 GN=CDC2B PE=2 SV=1
Length=294
Score = 203 bits (517), Expect = 2e-57, Method: Composition-based stats.
Identities = 74/291 (25%), Positives = 126/291 (43%), Gaps = 33/291 (11%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+
Sbjct 1 MEQYEKVEKIGEGTYGVV----YKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009
+ H +I++ + EK L LV EY+ L L+ ++ P + Q+ +F QI
Sbjct 57 EMQHRNIVRLQDVV--HSEKRLYLVFEYLDL-DLKKFMDSSPEFAKDQRQIKMFLYQILC 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
G+AY H+ +HRDL +N+L+D VK+ DFGLA+A R +++
Sbjct 114 GIAYCHSHRVLHRDLKPQNLLIDRSSNAVKLADFGLARAFGIP---VRTFTHEVVTLWYR 170
Query 1069 APECLKEYK-FYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVL 1122
APE L + + DVWS G E++ DS K + G + T
Sbjct 171 APEILLGSRHYSTPVDVWSVGCIFAEMINQRPLFPGDSEIDELFKIFRITGTPNEE-TWP 229
Query 1123 RLTELLERGERLPR----------PDKCPCEVYHLMKNCWETEASFRPTFE 1163
+T L + P+ P+ P + L+ + + + R T
Sbjct 230 GVTSLPDFKSAFPKWPAKDLATQVPNLEPAGL-DLLSSTCRLDPTRRITAR 279
Score = 167 bits (423), Expect = 8e-45, Method: Composition-based stats.
Identities = 46/266 (17%), Positives = 96/266 (36%), Gaps = 39/266 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
++ ++ +G+GT VY+ RDR + LK
Sbjct 1 MEQYEKVEKIGEGTYGVVYKA------------------------RDRATNETIALKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
L+ + SL+ ++ H ++ + V +V EY++ L ++
Sbjct 37 LEQEDEGVPSTAIREISLLKEMQHRNIVRLQDVVHSEKRLYLVFEYLDL-DLKKFMDSSP 95
Query 704 GHVPMAWKMVV-AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
++ + Q+ ++Y + ++H ++ +N+L+ R +S +KL+D G+
Sbjct 96 EFAKDQRQIKMFLYQILCGIAYCHSHRVLHRDLKPQNLLIDR------SSNAVKLADFGL 149
Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + + APE L G+ ST +D W G E+
Sbjct 150 ARAFGIPVRTFTHEVVTLWYRAPEILL-GSRHYSTPVDVWSVGCIFAEMINQRPLFPGDS 208
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844
E ++ E + P + +L
Sbjct 209 EIDELFKIFRITGTPNEETWPGVTSL 234
>sp|P24100|CDKA1_ARATH Cyclin-dependent kinase A-1 OS=Arabidopsis
thaliana OX=3702 GN=CDKA-1 PE=1 SV=1
Length=294
Score = 203 bits (517), Expect = 2e-57, Method: Composition-based stats.
Identities = 71/286 (25%), Positives = 122/286 (43%), Gaps = 31/286 (11%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+
Sbjct 1 MDQYEKVEKIGEGTYGVV----YKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009
+ H +I+K + EK L LV EY+ L L+ ++ P S L + + QI
Sbjct 57 EMQHSNIVKLQDVV--HSEKRLYLVFEYLDL-DLKKHMDSTPDFSKDLHMIKTYLYQILR 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
G+AY H+ +HRDL +N+L+D +K+ DFGLA+A R +++
Sbjct 114 GIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIP---VRTFTHEVVTLWYR 170
Query 1069 APECLKE-YKFYYASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIGIAQGQMTVL 1122
APE L + + D+WS G E+++ DS K ++G T
Sbjct 171 APEILLGSHHYSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYED-TWR 229
Query 1123 RLTELLERGERLP--RP-------DKCPCEVYHLMKNCWETEASFR 1159
+T L + P +P + L+ + + R
Sbjct 230 GVTSLPDYKSAFPKWKPTDLETFVPNLDPDGVDLLSKMLLMDPTKR 275
Score = 159 bits (402), Expect = 6e-42, Method: Composition-based stats.
Identities = 42/266 (16%), Positives = 92/266 (35%), Gaps = 39/266 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
+ ++ +G+GT VY+ RD+ + LK
Sbjct 1 MDQYEKVEKIGEGTYGVVYKA------------------------RDKVTNETIALKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702
L+ + SL+ ++ H+++ + V +V EY++ L +
Sbjct 37 LEQEDEGVPSTAIREISLLKEMQHSNIVKLQDVVHSEKRLYLVFEYLDL-DLKKHMDSTP 95
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ Q+ ++Y + ++H ++ +N+L+ R + +KL+D G+
Sbjct 96 DFSKDLHMIKTYLYQILRGIAYCHSHRVLHRDLKPQNLLIDRR------TNSLKLADFGL 149
Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + + APE L G++ ST +D W G E+
Sbjct 150 ARAFGIPVRTFTHEVVTLWYRAPEILL-GSHHYSTPVDIWSVGCIFAEMISQKPLFPGDS 208
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ E + + +L
Sbjct 209 EIDQLFKIFRIMGTPYEDTWRGVTSL 234
>sp|Q9M6A7|CLV1B_SOYBN Leucine-rich repeat receptor-like kinase
protein CLV1B OS=Glycine max OX=3847 GN=CLV1B PE=2 SV=1
Length=987
Score = 219 bits (558), Expect = 2e-57, Method: Composition-based stats.
Identities = 81/324 (25%), Positives = 133/324 (41%), Gaps = 25/324 (8%)
Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921
+ + R + NLA + + LK+ +G+G G V +
Sbjct 661 VTVYMMRRRKMNLAKTWKLTAFQRLNFKAEDVVECLKEENIIGKGGAGIVYRG-----SM 715
Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981
G VA+K L ++ G+K EI+ L + H +I++ G ++ E +L L EY+
Sbjct 716 PNGTDVAIKRLVGAGSGRNDYGFKAEIETLGKIRHRNIMRLLGYVSNK-ETNLLL-YEYM 773
Query 982 PLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDR 1035
P GSL ++L + A + +G+ YLH IHRD+ + N+LLD D
Sbjct 774 PNGSLGEWLHGAKGGHLKWEMRYKIAVEAAKGLCYLHHDCSPLIIHRDVKSNNILLDGDL 833
Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095
+ DFGLAK + + + S + APE K SDV+SFGV L EL+
Sbjct 834 EAHVADFGLAKFLYDPGASQSMSSIAGS-YGYIAPEYAYTLKVDEKSDVYSFGVVLLELI 892
Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL----PRPDKCPCE----VYHL 1147
++++G T L L + + L PR P ++++
Sbjct 893 IGRKPVGE-FGDGVDIVGWVN--KTRLELAQPSDAALVLAVVDPRLSGYPLTSVIYMFNI 949
Query 1148 MKNCWETEASFRPTFENLIPILKT 1171
C + RPT ++ +L
Sbjct 950 AMMCVKEMGPARPTMREVVHMLSE 973
Score = 187 bits (476), Expect = 3e-47, Method: Composition-based stats.
Identities = 52/327 (16%), Positives = 93/327 (28%), Gaps = 47/327 (14%)
Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPS 647
+ + + +G+G VY G V +K L
Sbjct 696 LKEENIIGKGGAGIVYRG-------------------------SMPNGTDVAIKRLVGAG 730
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHV 706
F + ++ H ++ + G N+++ EY+ +G L WL + GH+
Sbjct 731 SGRNDYGFKAEIETLGKIRHRNIMRLLGYVSNKETNLLLYEYMPNGSLGEWLHGAKGGHL 790
Query 707 PMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ +A + A L YL + ++H +V NILL A ++D G+
Sbjct 791 KWEMRYKIAVEAAKGLCYLHHDCSPLIIHRDVKSNNILLDGDLEAH-------VADFGLA 843
Query 764 LGAL------SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
S ++APE + D + FG LLE+ G P
Sbjct 844 KFLYDPGASQSMSSIAGSYGYIAPEYA--YTLKVDEKSDVYSFGVVLLELII-GRKP-VG 899
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877
+ E + P A L + + P I +
Sbjct 900 EFGDGVDIVGWVNKTRLELAQPSDAALVLAVVDPRLSGYPLTSVIYMFNIAMMCVKEMGP 959
Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLG 904
+ +
Sbjct 960 ARPTMREVVHMLSEPPHSATHTHNLIN 986
>sp|Q92241|PHO85_KLULA Negative regulator of the PHO system OS=Kluyveromyces
lactis (strain ATCC 8585 / CBS 2359 / DSM 70799
/ NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=PHO85 PE=3
SV=2
Length=304
Score = 204 bits (518), Expect = 2e-57, Method: Composition-based stats.
Identities = 64/300 (21%), Positives = 123/300 (41%), Gaps = 36/300 (12%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953
K++ +G G + V Y N TG VA+K +K D S +EI +++
Sbjct 4 PSQFKQLEKVGNGTYATV----YKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKE 59
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-------IGLAQLLLFAQQ 1006
L H++I++ E L LV E++ L+ ++ + + + + F Q
Sbjct 60 LKHDNIVRLFDVI--HTENKLTLVFEFMDN-DLKKFMDNRNKGNSHKGLEMDLVKYFQWQ 116
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
+ +G+A+ H +HRDL +N+L++N +K+GDFGLA+A ++
Sbjct 117 LLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIP---VNTFSSEVVTLW 173
Query 1067 WYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRL 1124
+ AP+ L + + + D+WS G L E++ S + L+LI G
Sbjct 174 YRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW 233
Query 1125 TELLE-RGERLPRPDKCPCEVYHLMKN----------------CWETEASFRPTFENLIP 1167
++ + P P ++ L++N + R + ++ +
Sbjct 234 PQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALN 293
Score = 167 bits (424), Expect = 8e-45, Method: Composition-based stats.
Identities = 48/273 (18%), Positives = 95/273 (35%), Gaps = 43/273 (16%)
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
V + QL +G GT VY+G + G + V LK
Sbjct 2 VAPSQFKQLEKVGNGTYATVYKGLNKTTG------------------------VYVALKE 37
Query 644 LDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702
+ + SLM ++ H ++ + V + +V E++++ L ++
Sbjct 38 VKLDSEEGTPSTAIREISLMKELKHDNIVRLFDVIHTENKLTLVFEFMDN-DLKKFMDNR 96
Query 703 R-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757
+ M QL +++ ++H ++ +N+L+ G +KL
Sbjct 97 NKGNSHKGLEMDLVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQ-------LKL 149
Query 758 SDPGVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813
D G+ + V + + AP+ L G+ + T++D W G L E+
Sbjct 150 GDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM-GSRNYCTSIDIWSCGCILAEMIMGKPL 208
Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTS 846
S + + + E + PQ+ L
Sbjct 209 FPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK 241
>sp|A3LN91|HOG1_PICST Mitogen-activated protein kinase HOG1 OS=Scheffersomyces
stipitis (strain ATCC 58785 / CBS 6054 / NBRC
10063 / NRRL Y-11545) OX=322104 GN=HOG1 PE=3 SV=2
Length=385
Score = 206 bits (525), Expect = 2e-57, Method: Composition-based stats.
Identities = 65/289 (22%), Positives = 106/289 (37%), Gaps = 32/289 (11%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRT 953
+ +G G FG V + TG+ VAVK + K +E+ +L+
Sbjct 21 NRYTDLNPVGMGAFGLVC----SAVDKLTGQNVAVKKIMKPFSTSVLAKRTYRELKLLKH 76
Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013
L HE++I E + V E L L + + F QI G+ Y
Sbjct 77 LKHENLITLDDIFLSPLED-IYFVNEL-QGTDLHRLLTSRPLEKQFIQYFTYQILRGLKY 134
Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073
+H+ IHRDL N+L++ + +KI DFGLA+ Y S ++ APE +
Sbjct 135 IHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIM 188
Query 1074 KE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------T 1120
K+ D+WS G L E++ + EL+G +
Sbjct 189 LTWQKYDTEVDLWSVGCILAEMIEGKPLFPGKDHVHQFSIITELLGSPPPDVIDTICSEN 248
Query 1121 VLRLTELLERGERLPRPDKCP------CEVYHLMKNCWETEASFRPTFE 1163
LR + L + +P ++ E L+ + R +
Sbjct 249 TLRFVQSLPHRDPIPFNERFAQCTHVEPEAIDLLAKMLIFDPKKRISAA 297
Score = 135 bits (341), Expect = 6e-33, Method: Composition-based stats.
Identities = 47/324 (15%), Positives = 89/324 (27%), Gaps = 38/324 (12%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
V+E R G + D+ V +K ++ P +A Y
Sbjct 13 FGTVFEITNRYTDLNPVGMGAF---GLVCSAVDKLTGQNVAVKKIMKPFSTSVLAKRTYR 69
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H +L + + + + V E + L L + +
Sbjct 70 ELKLLKHLKHENLITLDDIFLSPLEDIYFVNEL-QGTDLHRLLTSR--PLEKQFIQYFTY 126
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + ++H ++ NIL+ + +K+ D G+ V
Sbjct 127 QILRGLKYIHSAGVIHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 179
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--------------------FDGEAPL 815
+ APE + T +D W G L E+ G P
Sbjct 180 RYYRAPE-IMLTWQKYDTEVDLWSVGCILAEMIEGKPLFPGKDHVHQFSIITELLGSPPP 238
Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875
E+ + LP +QC EP +L + + +
Sbjct 239 DVIDTICSENTLRFVQSLPHRDPIPFNERFAQCTHVEPEAIDLLAKMLIFDPKKRISAAS 298
Query 876 DVLTVNPDSPASDPTVFHKRYLKK 899
+ +
Sbjct 299 ALTHPYMEPYHDPTDEPICETKFD 322
>sp|Q5GIG6|TNI3K_MOUSE Serine/threonine-protein kinase TNNI3K
OS=Mus musculus OX=10090 GN=Tnni3k PE=2 SV=4
Length=834
Score = 217 bits (553), Expect = 2e-57, Method: Composition-based stats.
Identities = 72/327 (22%), Positives = 129/327 (39%), Gaps = 30/327 (9%)
Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911
+P S+ ++ L +++ + + ++ +G G FGKV
Sbjct 417 QPGGDGSYVSVPSPLGKIKSMTKEKADVLLLRAELPSRFHLQLSEIEFHEIIGSGSFGKV 476
Query 912 SLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969
++VA+K +A+ C + +E+ IL L H ++++ G C D
Sbjct 477 YKG------RCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVVQFVGACLD- 529
Query 970 GEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHA--QHYIHRDLA 1025
+V +Y+ GSL L + L L+ A + +GM YLH+ Q IHRDL
Sbjct 530 DPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHSLTQPIIHRDLN 589
Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKFYYASDV 1084
+ N+LL D + DFG ++ + E ++ G+ + W APE + ++ +DV
Sbjct 590 SHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGN--LRWMAPEVFTQCTRYTIKADV 647
Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144
+S+ + L+ELLT ++ R P P +
Sbjct 648 FSYALCLWELLTGEIPFAH--------------LKPAAAAADMAYHHIRPPIGYSIPKPI 693
Query 1145 YHLMKNCWETEASFRPTFENLIPILKT 1171
L+ W RP F ++ L+
Sbjct 694 SSLLMRGWNACPEGRPEFSEVVRKLEE 720
Score = 209 bits (531), Expect = 2e-54, Method: Composition-based stats.
Identities = 62/331 (19%), Positives = 125/331 (38%), Gaps = 59/331 (18%)
Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615
E ++++++R S L LS++ FH + +G G+ VY+GR R +
Sbjct 439 KEKADVLLLRAELPSRFHLQLSEIEFHEI----------IGSGSFGKVYKGRCRNK---- 484
Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETASLMSQVSHTHLAF 672
V +K + F S++ Q++H +
Sbjct 485 ----------------------IVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVVQ 522
Query 673 VHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN--KN 729
G C+ P + +VT+Y+ G L L ++ + + K+++A +A + YL + +
Sbjct 523 FVGACLDDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHSLTQP 582
Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-----GALSREERVERIPWLAPECL 784
++H ++ NILL G A ++D G + ++ + W+APE
Sbjct 583 IIHRDLNSHNILLYEDGHAV-------VADFGESRFLQSLDEDNMTKQPGNLRWMAPEVF 635
Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQL 841
+ D + + L E+ GE P P+ ++ + + +
Sbjct 636 TQCTR-YTIKADVFSYALCLWELL-TGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPI 693
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872
++L + P RP F ++R L +
Sbjct 694 SSLLMRGWNACPEGRPEFSEVVRKLEECLCN 724
>sp|Q54N73|7TMK1_DICDI Seven transmembrane domain-containing tyrosine-protein
kinase 1 OS=Dictyostelium discoideum OX=44689
GN=7tmk1 PE=3 SV=1
Length=691
Score = 215 bits (547), Expect = 2e-57, Method: Composition-based stats.
Identities = 71/295 (24%), Positives = 124/295 (42%), Gaps = 40/295 (14%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-----GPQHRSGW 944
K + +GEG+FG+V + G +VAVK L + G + + +
Sbjct 356 FYIRFNEFKFGQVIGEGYFGEVRKAVWK------GAVVAVKILHRNSFRNTDGNKEENVF 409
Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ----L 1000
+E+ IL L H +++++ G C + +V EY+ GSL L + Q
Sbjct 410 LKEVAILSILRHPNVLQFLGVCSETNLNG--IVTEYMGGGSLDRLLTDRYFLIKQNPILA 467
Query 1001 LLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYR 1056
A I GM YLH +HRDL+ +N+LLD + K+ DFGL+K E
Sbjct 468 WNMAISIARGMFYLHDWKPNPILHRDLSTKNILLDESLTIAKVADFGLSK------EQGF 521
Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIA 1115
+ + APE + +DV+SFG+ ++ ++T +Q+ P K L
Sbjct 522 EMTSTVGHLCYQAPEVFIGELYTPKADVYSFGLLVWCIITGEQPNQNLQPLKMAHLAAYE 581
Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ + + + + + L++ CW+ RP+F ++ L+
Sbjct 582 NYRPPMPQPMDPMWEN------------LGKLIEMCWKKSPEERPSFSFILDFLE 624
Score = 207 bits (528), Expect = 6e-55, Method: Composition-based stats.
Identities = 64/305 (21%), Positives = 108/305 (35%), Gaps = 57/305 (19%)
Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637
QLS + E +G+G V + +
Sbjct 352 QLSAFYIRFNEFKFGQVIGEGYFGEVRKAVWKG--------------------------A 385
Query 638 RVVLKVLDPSH---HDIALA---FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691
V +K+L + D F + +++S + H ++ GVC N +VTEY+
Sbjct 386 VVAVKILHRNSFRNTDGNKEENVFLKEVAILSILRHPNVLQFLGVCSETNLNGIVTEYMG 445
Query 692 HGPLDVWLRRE----RGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLAR 744
G LD L + + +AW M ++ +A + YL + ++H ++ +NILL
Sbjct 446 GGSLDRLLTDRYFLIKQNPILAWNMAIS--IARGMFYLHDWKPNPILHRDLSTKNILLDE 503
Query 745 LGLAEGTSPFIKLSDPGVGL-GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803
K++D G+ V + + APE G + D + FG
Sbjct 504 SLT------IAKVADFGLSKEQGFEMTSTVGHLCYQAPEVFIGEL--YTPKADVYSFGLL 555
Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHR------LPEPSCPQLATLTSQCLTYEPTQRP 857
+ GE P Q+ P + H ++ +P L L C P +RP
Sbjct 556 VW-CIITGEQPNQNLQPLKMAHLAAYENYRPPMPQPMDPMWENLGKLIEMCWKKSPEERP 614
Query 858 SFRTI 862
SF I
Sbjct 615 SFSFI 619
>sp|O00141|SGK1_HUMAN Serine/threonine-protein kinase Sgk1 OS=Homo
sapiens OX=9606 GN=SGK1 PE=1 SV=2
Length=431
Score = 208 bits (529), Expect = 2e-57, Method: Composition-based stats.
Identities = 65/338 (19%), Positives = 116/338 (34%), Gaps = 29/338 (9%)
Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885
F +++ ++A + C E + + +
Sbjct 27 FMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINLG 86
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSG 943
S ++ +G+G FGKV L + AVK L KA +
Sbjct 87 PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEV----FYAVKVLQKKAILKKKEEKH 142
Query 944 WKQEID-ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLL 1001
E + +L+ + H ++ Q L V++Y+ G L +L R +
Sbjct 143 IMSERNVLLKNVKHPFLVGLH--FSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRAR 200
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061
+A +I + YLH+ + ++RDL N+LLD+ + + DFGL K E E+
Sbjct 201 FYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCK---ENIEHNSTTSTF 257
Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121
+ APE L + + D W G LYE+L + T
Sbjct 258 CGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPF--------------YSRNTA 303
Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+L + +L HL++ + + + R
Sbjct 304 EMYDNILNKPLQLK--PNITNSARHLLEGLLQKDRTKR 339
Score = 163 bits (412), Expect = 6e-42, Method: Composition-based stats.
Identities = 68/314 (22%), Positives = 110/314 (35%), Gaps = 45/314 (14%)
Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
PQ E N + + +NL S + L +G+G+ V
Sbjct 62 QPQEPELMN-ANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKV-------- 112
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETAS-LMSQVSH 667
+ R + +E+ +KVL + L+ V H
Sbjct 113 ----------------LLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156
Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727
L +H + V +Y+ G L L+RER + + A ++ASAL YL +
Sbjct 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARF-YAAEIASALGYLHS 215
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREERVERIPWLAPEC 783
N+V+ ++ NILL G I L+D G+ + + +LAPE
Sbjct 216 LNIVYRDLKPENILLDSQG-------HIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEV 268
Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPSCPQLA 842
L +D W GA L E+ G P SR+ +E + + +L
Sbjct 269 LH--KQPYDRTVDWWCLGAVLYEML-YGLPPFYSRNTAEMYDNILNKPLQLKPNITNSAR 325
Query 843 TLTSQCLTYEPTQR 856
L L + T+R
Sbjct 326 HLLEGLLQKDRTKR 339
>sp|Q7Z8E9|STE20_PYRO7 Serine/threonine-protein kinase MST20 OS=Pyricularia
oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
OX=242507 GN=MST20 PE=3 SV=3
Length=914
Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats.
Identities = 55/274 (20%), Positives = 112/274 (41%), Gaps = 23/274 (8%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
+ + +G+G G V G+ +VA+K + + P+ + EI +++
Sbjct 630 PREIYRSFTKIGQGASGGVYTGH----ERGSNRLVAIKQMNLEQQPK-KDLIINEILVMK 684
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012
H +I+ + GE L +VME++ GSL D + + + Q+ ++ G+
Sbjct 685 DSSHPNIVNFIDSYLCGGE--LWVVMEFMEGGSLTDVVTFNIMTEGQIASVCRETLLGLQ 742
Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072
+LH++ IHRD+ + N+LL + +K+ DFG + +E R +W APE
Sbjct 743 HLHSKGVIHRDIKSDNILLSMEGNIKLTDFGFCATI---NEAQNKRTTMVGTPYWMAPEV 799
Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132
+ ++ D+WS G+ E++ + P E A + ++ + G
Sbjct 800 VTRKEYGRKVDIWSLGIMAIEMI------EGEPPYLTESPLRALWLIATNGTPQIKDEG- 852
Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ + + R + +L+
Sbjct 853 ------NMSPVFRDFLYFALKVDPDKRASAHDLL 880
Score = 181 bits (459), Expect = 3e-45, Method: Composition-based stats.
Identities = 60/296 (20%), Positives = 96/296 (32%), Gaps = 45/296 (15%)
Query 585 DQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
D +EI + +GQG VY G +RG V +K
Sbjct 629 DPREIYRSFTKIGQGASGGVYTGH------------------------ERGSNRLVAIKQ 664
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
++ +M SH ++ + G E +V E++E G L +
Sbjct 665 MNLEQQPKKDLIINEILVMKDSSHPNIVNFIDSYLCGGELWVVMEFMEGGSLTDVV--TF 722
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ V ++ L +L +K ++H ++ NILL+ G IKL+D G
Sbjct 723 NIMTEGQIASVCRETLLGLQHLHSKGVIHRDIKSDNILLSMEG-------NIKLTDFGFC 775
Query 764 LGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
R V W+APE + +D W G +E+ +GE P + S
Sbjct 776 ATINEAQNKRTTMVGTPYWMAPEVVT--RKEYGRKVDIWSLGIMAIEMI-EGEPPYLTES 832
Query 820 PSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P P L +P +R S +LR
Sbjct 833 PLRALWLIATNGTPQIKDEGNMSPVFRDFLYFALKVDPDKRASAHDLLRHEFMNLC 888
>sp|Q9H4B4|PLK3_HUMAN Serine/threonine-protein kinase PLK3 OS=Homo
sapiens OX=9606 GN=PLK3 PE=1 SV=2
Length=646
Score = 214 bits (544), Expect = 3e-57, Method: Composition-based stats.
Identities = 67/267 (25%), Positives = 110/267 (41%), Gaps = 28/267 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960
LG+G F + CY+ T+ TG AVK + P R EI++ R L H HI+
Sbjct 68 LGKGGFAR----CYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIV 123
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
++ ED ++ + +E SL + RH++ ++ + +QI G+ YLH +
Sbjct 124 RFSHHFEDAD--NIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 181
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDL N + + +K+GDFGLA + + + + APE L
Sbjct 182 LHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKT---ICGTPNYVAPEVLLRQGHG 238
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
+DVWS G +Y LL SPP + +L R + + P
Sbjct 239 PEADVWSLGCVMYTLLCG-----SPPFETADL-------KETYRCIKQV----HYTLPAS 282
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLI 1166
L+ RP+ + ++
Sbjct 283 LSLPARQLLAAILRASPRDRPSIDQIL 309
Score = 150 bits (379), Expect = 3e-36, Method: Composition-based stats.
Identities = 52/342 (15%), Positives = 91/342 (27%), Gaps = 53/342 (15%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--- 647
+ LG+G YE D +KV+ S
Sbjct 64 KGRLLGKGGFARCYEA------------------------TDTETGSAYAVKVIPQSRVA 99
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
L + H H+ + E L + + R +
Sbjct 100 KPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLA-HIWKARHTLL 158
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
+Q+ S L YL + ++H ++ N + + +K+ D G+
Sbjct 159 EPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITE-------NMELKVGDFGLAARLE 211
Query 768 S----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
++ ++APE L D W G + + G P ++ E
Sbjct 212 PPEQRKKTICGTPNYVAPEVLL--RQGHGPEADVWSLGCVMYTLLC-GSPPFETADLKET 268
Query 824 EH-FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882
Q + LP L + L P RPS ILR + + + +
Sbjct 269 YRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFFTKGYTPDRLPISSC 328
Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924
+ R L F KV+ +
Sbjct 329 VTVPDLTPPNPARSL----------FAKVTKSLFGRKKKSKN 360
>sp|Q56UN5|M3K19_HUMAN Mitogen-activated protein kinase kinase
kinase 19 OS=Homo sapiens OX=9606 GN=MAP3K19 PE=2 SV=1
Length=1328
Score = 221 bits (562), Expect = 3e-57, Method: Composition-based stats.
Identities = 71/281 (25%), Positives = 121/281 (43%), Gaps = 31/281 (11%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG-----PQHRSGWKQEIDIL 951
K LG+G +G V G+++AVK + D + ++E+D+L
Sbjct 1061 WTKGEILGKGAYGTVYCG-----LTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLL 1115
Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEG 1010
+ L H +I+ Y G C E ++ + ME+VP GS+ + R + + +QI +G
Sbjct 1116 KALKHVNIVAYLGTCLQ--ENTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQG 1173
Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP----EGHEYYRVREDGDSPVF 1066
+AYLH +HRD+ NV+L ++K+ DFG A+ + G ++ +P +
Sbjct 1174 VAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTP-Y 1232
Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126
W APE + E + SD+WS G T++E+ T P + +
Sbjct 1233 WMAPEVINESGYGRKSDIWSIGCTVFEMATGKP----PLASMDRMAAMFYIGAH------ 1282
Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
RG P PD ++ C + RP+ L+
Sbjct 1283 ---RGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQLLK 1320
Score = 179 bits (454), Expect = 3e-44, Method: Composition-based stats.
Identities = 62/293 (21%), Positives = 103/293 (35%), Gaps = 46/293 (16%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
T+ LG+G VY G ++ +D + L ++
Sbjct 1062 TKGEILGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEY---------------- 1105
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
E L+ + H ++ G C++ + E+V G + + G +P
Sbjct 1106 ---RKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSII-NRFGPLPEM 1161
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----- 764
+Q+ ++YL +VH ++ G N++L G+ IKL D G
Sbjct 1162 VFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGI-------IKLIDFGCARRLAWA 1214
Query 765 ---GALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
G S + W+APE + + D W G T+ E+ G+ PL S
Sbjct 1215 GLNGTHSDMLKSMHGTPYWMAPEVI--NESGYGRKSDIWSIGCTVFEMA-TGKPPLASMD 1271
Query 820 PSEKEHFYQRQHR-----LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
FY HR LP+ A CLT + +RPS +L+
Sbjct 1272 -RMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQLLKHSF 1323
>sp|Q10407|MKH1_SCHPO MAP kinase kinase kinase mkh1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=mkh1
PE=3 SV=1
Length=1116
Score = 220 bits (560), Expect = 3e-57, Method: Composition-based stats.
Identities = 77/312 (25%), Positives = 128/312 (41%), Gaps = 38/312 (12%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--------- 941
K +G G +GKV L N TGE++AVK ++ R
Sbjct 819 QNATFKWMKGELIGNGTYGKVFLAM----NINTGELIAVKQVEIPQTINGRHDQLRKDIV 874
Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL 1001
EI ++ L H +I++Y G ++ E + + +EYV GS+ L + QL+
Sbjct 875 DSINAEISMIADLDHLNIVQYLGF--EKTETDISIFLEYVSGGSIGRCLRNYGPFEEQLV 932
Query 1002 LFA-QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060
F +Q+ G++YLH++ IHRDL A N+L+D D + KI DFG++K +
Sbjct 933 RFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDFDGVCKISDFGISKH-SDNVYDNDANLS 991
Query 1061 GDSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
+FW APE + + DVWS G + E+L +
Sbjct 992 MQGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRRPWST--------------D 1037
Query 1119 MTVLRLTELLERGERLPRPDK----CPCEVYHLMKNCWETEASFRPTFENLIPI-LKTVH 1173
+ + +L + P P + E + C+ A RPT E L+
Sbjct 1038 EAIQAMFKLGTEKKAPPIPSELVSQVSPEAIQFLNACFTVNADVRPTAEELLNHPFMKCD 1097
Query 1174 EKYQGQAPSVFS 1185
E++ + +++
Sbjct 1098 EEFNFKDTNLYD 1109
Score = 184 bits (466), Expect = 7e-46, Method: Composition-based stats.
Identities = 83/557 (15%), Positives = 165/557 (30%), Gaps = 82/557 (15%)
Query 338 GSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHR 397
S S+ + +D +P WA + K+ + +
Sbjct 594 SSKSSNSLKESVEALSEIPFEDAPALDESDLSGDPFWA----------IQPKQSSSQVPK 643
Query 398 QDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHG---P 454
+++ ++ L A ++ +E++ P+ G
Sbjct 644 ENHHNIQSKLSINTEA----------------ATDLKANELSSPKTPE----YCRGDDRS 683
Query 455 LLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAF 514
+ + +LR I S + + + D + R FP D
Sbjct 684 ISLSPLSYRLRKSKH---IRESPPSSKVINSGNWEVRPSADDLYEDVDRFFPRYDLDKVL 740
Query 515 VLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARAS---- 570
V++ + + + R+ + ++R +
Sbjct 741 VVDQSRMVSSPSKVSIRPKMKSVRLLAREASEARKEIRHNARRNKSGNLLRRSSTKLWGS 800
Query 571 ------PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
P T S + + + +G GT V+ +G+ K +
Sbjct 801 RIVELKPDTTITSGSVVSQNATFKWMKGELIGNGTYGKVFLAM--NINTGELIAVKQVEI 858
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
+ GR D DI + S+++ + H ++ G +
Sbjct 859 PQTINGRH------------DQLRKDIVDSINAEISMIADLDHLNIVQYLGFEKTETDIS 906
Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744
+ EYV G + LR G V++Q+ LSYL +K ++H ++ N+L+
Sbjct 907 IFLEYVSGGSIGRCLR-NYGPFEEQLVRFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDF 965
Query 745 LGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKW 798
G+ K+SD G+ + I W+APE + S +D W
Sbjct 966 DGV-------CKISDFGISKHSDNVYDNDANLSMQGSIFWMAPEVIHNDHQGYSAKVDVW 1018
Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------CPQLATLTSQCLTY 851
G +LE+ G P + + + + P P+ + C T
Sbjct 1019 SLGCVVLEMLA-GRRPWSTDEAIQAMFKLGTEKKAPPIPSELVSQVSPEAIQFLNACFTV 1077
Query 852 EPTQRPSFRTILRDLTR 868
RP+ +L
Sbjct 1078 NADVRPTAEELLNHPFM 1094
>sp|Q08942|NRKA_TRYBB Putative serine/threonine-protein kinase
A OS=Trypanosoma brucei brucei OX=5702 GN=NRKA PE=2 SV=1
Length=431
Score = 208 bits (529), Expect = 3e-57, Method: Composition-based stats.
Identities = 63/273 (23%), Positives = 109/273 (40%), Gaps = 29/273 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G +G+ Y + G + K + + + + + EI L H +II+
Sbjct 26 VGLGSYGE----AYVAESVEDGSLCVAKVMDLSKMSQRDKRYAQSEIKCLANCNHPNIIR 81
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYLH 1015
Y + + L +VME+ G+L + + + L Q+C + Y+H
Sbjct 82 YIE--DHEENDRLLIVMEFADSGNLDEQIKLRGSGDARYFQEHEALFLFLQLCLALDYIH 139
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ +HRD+ + NVLL + LVK+GDFG + + +P ++ APE
Sbjct 140 SHKMLHRDIKSANVLLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTP-YYLAPELWNN 198
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
++ +DVWS GV LYE++ P L G L + G P
Sbjct 199 KRYNKKADVWSLGVLLYEIM-----GMKKPFSASNLKG----------LMSKVLAGTYAP 243
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168
PD E ++ + + RP+ + I
Sbjct 244 LPDSFSSEFKRVVDGILVADPNDRPSVREIFQI 276
Score = 150 bits (380), Expect = 9e-38, Method: Composition-based stats.
Identities = 54/290 (19%), Positives = 91/290 (31%), Gaps = 29/290 (10%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ LG GR + G G + D L V KV+D S
Sbjct 5 FSTILGTDGSG----GRCKYLNKGIVGLGSYGEAYVAESVEDGS--LCVA-KVMDLSKMS 57
Query 651 IALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR----RERG 704
Y ++ +H ++ ++V E+ + G LD ++ +
Sbjct 58 QRDKRYAQSEIKCLANCNHPNIIRYIEDHEENDRLLIVMEFADSGNLDEQIKLRGSGDAR 117
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + + QL AL Y+ + ++H ++ N+LL GL +KL D G
Sbjct 118 YFQEHEALFLFLQLCLALDYIHSHKMLHRDIKSANVLLTSTGL-------VKLGDFGFSH 170
Query 765 GALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL-QS 817
+LAPE + D W G L EI + +
Sbjct 171 QYEDTVSGVVASTFCGTPYYLAPEL--WNNKRYNKKADVWSLGVLLYEIMGMKKPFSASN 228
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ LP+ + + L +P RPS R I +
Sbjct 229 LKGLMSKVLAGTYAPLPDSFSSEFKRVVDGILVADPNDRPSVREIFQIPY 278
>sp|P28582|CDPK_DAUCA Calcium-dependent protein kinase OS=Daucus
carota OX=4039 PE=2 SV=2
Length=532
Score = 211 bits (536), Expect = 3e-57, Method: Composition-based stats.
Identities = 72/301 (24%), Positives = 118/301 (39%), Gaps = 30/301 (10%)
Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL- 932
V ++ P + ++LG G FG V Y T + +G++ A K++
Sbjct 58 PRQVHRPESNTILGKPFEDIRGKYTLGKELGRGQFGCV----YQCTENSSGQLYACKSIL 113
Query 933 -KADCGPQHRSGWKQEIDILRTLYH-EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-Y 989
+ + K+EI IL+ L +I+++KG ED+ +S+ LVME G L D
Sbjct 114 KRKLVSKNDKEDIKREIQILQHLSGQPNIVEFKGVFEDR--QSVHLVMELCAGGELFDRI 171
Query 990 LPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAK 1046
+ + +QI + H +HRDL N LL D D ++K DFGL+
Sbjct 172 IAQGHYSERAAATICRQIVNVVHVCHFMGVMHRDLKPENFLLSSKDKDAMLKATDFGLSV 231
Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106
+ EG Y + ++ APE L+ + D+WS GV LY LL+
Sbjct 232 FIEEGKVY----RNIVGSAYYVAPEVLRRS-YGKEIDIWSAGVILYILLSGVPPF----- 281
Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ + E + E P P L++ + R T ++
Sbjct 282 ------WAENEKGIFDAILEGVIDFESEPWP-SVSNSAKDLVRKMLTQDPRRRITSAQVL 334
Query 1167 P 1167
Sbjct 335 D 335
Score = 141 bits (355), Expect = 8e-34, Method: Composition-based stats.
Identities = 51/307 (17%), Positives = 94/307 (31%), Gaps = 40/307 (13%)
Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630
P + + F + + + T LG+G VY + SG K + LV
Sbjct 64 PESNTILGKPFEDI-RGKYTLGKELGRGQFGCVY--QCTENSSGQLYACKSILKRKLVSK 120
Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS-HTHLAFVHGVCVRGPENIMVTEY 689
D+ ++ +S ++ GV +V E
Sbjct 121 NDK-------------------EDIKREIQILQHLSGQPNIVEFKGVFEDRQSVHLVMEL 161
Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749
G L + + GH + +Q+ + + ++H ++ N LL+ +
Sbjct 162 CAGGELFDRIIAQ-GHYSERAAATICRQIVNVVHVCHFMGVMHRDLKPENFLLSS----K 216
Query 750 GTSPFIKLSDPGVGLGALSREER---VERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806
+K +D G+ + + V ++APE L S +D W G L
Sbjct 217 DKDAMLKATDFGLSVFIEEGKVYRNIVGSAYYVAPEVLR---RSYGKEIDIWSAGVILY- 272
Query 807 ICFDGEAPLQ-----SRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861
I G P + E + L + LT +P +R +
Sbjct 273 ILLSGVPPFWAENEKGIFDAILEGVIDFESEPWPSVSNSAKDLVRKMLTQDPRRRITSAQ 332
Query 862 ILRDLTR 868
+L
Sbjct 333 VLDHPWM 339
>sp|P59241|AURKA_RAT Aurora kinase A OS=Rattus norvegicus OX=10116
GN=Aurka PE=1 SV=1
Length=397
Score = 207 bits (526), Expect = 3e-57, Method: Composition-based stats.
Identities = 64/296 (22%), Positives = 109/296 (37%), Gaps = 33/296 (11%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRS-GWKQEI 948
+ R LG+G FG V L + ++A+K L K ++E+
Sbjct 120 QWTLEDFDIGRPLGKGKFGNVYL----AREKQSKFILALKVLFKVQLEKAGVEHQLRREV 175
Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQI 1007
+I L H +I++ G D + L++EY PLG++ L + + + ++
Sbjct 176 EIQSHLRHPNILRLYGYFHDAT--RVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 233
Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067
++Y H++ IHRD+ N+LL ++ +KI DFG + P R + +
Sbjct 234 ANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSR-----RTTLCGTLDY 288
Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
PE ++ D+WS GV YE L + A R
Sbjct 289 QPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFE------------AHTYQETYRRISR 336
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183
+E PD L+ + +S R T + L+ K P
Sbjct 337 VE----FTFPDFVTEGARDLISRLLKHNSSQRLTLAEV---LEHPWIKANSSKPPT 385
Score = 178 bits (452), Expect = 2e-47, Method: Composition-based stats.
Identities = 62/350 (18%), Positives = 121/350 (35%), Gaps = 48/350 (14%)
Query 524 PSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHR 583
P +++L AA R + ++ PQP + N + +
Sbjct 68 PVLKQLPAA---SGPRPASRLSNPQKSEQPQPAASGN----NSEKEQTSIQKTEDSKKRQ 120
Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643
++ LG+G NVY R++ + + LKV
Sbjct 121 WTLEDFDIGRPLGKGKFGNVYLA------------------------REKQSKFILALKV 156
Query 644 LDPSHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
L + + + S + H ++ ++G ++ EY G + L+
Sbjct 157 LFKVQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQ 216
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ +LA+ALSY +K ++H ++ N+LL G++ +K++D
Sbjct 217 KL-SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLL-------GSNGELKIADF 268
Query 761 GVGLGALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
G + A S R + + PE + G + +D W G E G P ++
Sbjct 269 GWSVHAPSSRRTTLCGTLDYQPPEMIEGRMH--DEKVDLWSLGVLCYEFLV-GMPPFEAH 325
Query 819 SPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
+ E + + P+ L S+ L + +QR + +L
Sbjct 326 TYQETYRRISRVEFTFPDFVTEGARDLISRLLKHNSSQRLTLAEVLEHPW 375
>sp|P26696|MK01_XENLA Mitogen-activated protein kinase 1 OS=Xenopus
laevis OX=8355 GN=mapk1 PE=1 SV=3
Length=361
Score = 205 bits (522), Expect = 3e-57, Method: Composition-based stats.
Identities = 61/276 (22%), Positives = 106/276 (38%), Gaps = 24/276 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962
+GEG +G V ++ VA+K + + +EI IL HE+II
Sbjct 34 IGEGAYGMVCSAH----DNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFKHENIIGI 89
Query 963 KGCCEDQG---EKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
K + +V + + L L + + F QI G+ Y+H+ +
Sbjct 90 NDIIRAPTIEQMKDVYIVQDLME-TDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANV 148
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC-LKEYKF 1078
+HRDL N+LL+ +KI DFGLA+ H++ + + ++ APE L +
Sbjct 149 LHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGY 208
Query 1079 YYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGI--AQGQMTVLRLTELLERGERL 1134
+ D+WS G L E+L++ + + ++GI + Q + + L R L
Sbjct 209 TKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLL 268
Query 1135 PRP-----------DKCPCEVYHLMKNCWETEASFR 1159
P + L+ R
Sbjct 269 SLPHKNKVPWNRLFPNADPKALDLLDKMLTFNPHKR 304
Score = 132 bits (332), Expect = 5e-32, Method: Composition-based stats.
Identities = 37/245 (15%), Positives = 80/245 (33%), Gaps = 48/245 (20%)
Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA-L 653
+G+G V D ++RV +K + P H
Sbjct 34 IGEGAYGMVCSAH------------------------DNVNKVRVAIKKISPFEHQTYCQ 69
Query 654 AFYETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDVWLRRERGHVPM 708
++ + H ++ ++ + + +V + +E L L+ + H+
Sbjct 70 RTLREIKILLRFKHENIIGINDIIRAPTIEQMKDVYIVQDLME-TDLYKLLKTQ--HLSN 126
Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768
Q+ L Y+ + N++H ++ N+LL T+ +K+ D G+ A
Sbjct 127 DHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLN-------TTCDLKICDFGLARVADP 179
Query 769 REERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821
+ + APE + + + ++D W G L E+ +
Sbjct 180 DHDHTGFLTEYVATRWYRAPE-IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLD 238
Query 822 EKEHF 826
+ H
Sbjct 239 QLNHI 243
>sp|Q9NRH2|SNRK_HUMAN SNF-related serine/threonine-protein kinase
OS=Homo sapiens OX=9606 GN=SNRK PE=1 SV=2
Length=765
Score = 216 bits (550), Expect = 3e-57, Method: Composition-based stats.
Identities = 65/269 (24%), Positives = 106/269 (39%), Gaps = 31/269 (12%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHII 960
LG GHF V L + TGE VAVK + K QE+ ++ + H +I+
Sbjct 21 TLGRGHFAVVKL----ARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHPNIV 76
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQH 1018
+ + Q + L L++E G + DY+ +H + + QI ++Y H H
Sbjct 77 RLYEVIDTQTK--LYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134
Query 1019 YIHRDLAARN-VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL N V + LVK+ DFG + G + + + APE L +
Sbjct 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKL----TTSCGSLAYSAPEILLGDE 190
Query 1078 FY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
+ A D+WS GV L+ L+ Q A T+ + + +
Sbjct 191 YDAPAVDIWSLGVILFMLVCGQPPFQE-----------ANDSETLTMIMDC-----KYTV 234
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENL 1165
P E L+ + + R + E +
Sbjct 235 PSHVSKECKDLITRMLQRDPKRRASLEEI 263
Score = 172 bits (437), Expect = 5e-43, Method: Composition-based stats.
Identities = 50/281 (18%), Positives = 95/281 (34%), Gaps = 38/281 (14%)
Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652
LG+G V R G +V +KV+D + D
Sbjct 20 KTLGRGHFAVVKLARHVFTGE------------------------KVAVKVIDKTKLDTL 55
Query 653 LA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
++ M V H ++ ++ V + ++ E + G + ++ + +
Sbjct 56 ATGHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDL 115
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGAL 767
Q+ A+SY ++VH ++ N+ + +KL+D G
Sbjct 116 AKKYFAQIVHAISYCHKLHVVHRDLKPENV------VFFEKQGLVKLTDFGFSNKFQPGK 169
Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
+ + APE L G + A+D W G L + G+ P Q + SE
Sbjct 170 KLTTSCGSLAYSAPEILLGDEYD-APAVDIWSLGVIL-FMLVCGQPPFQEANDSETLTMI 227
Query 828 QR-QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
++ +P + L ++ L +P +R S I
Sbjct 228 MDCKYTVPSHVSKECKDLITRMLQRDPKRRASLEEIENHPW 268
>sp|Q55GV3|PAKC_DICDI Serine/threonine-protein kinase pakC OS=Dictyostelium
discoideum OX=44689 GN=pakC PE=1 SV=2
Length=477
Score = 209 bits (532), Expect = 3e-57, Method: Composition-based stats.
Identities = 60/278 (22%), Positives = 114/278 (41%), Gaps = 26/278 (9%)
Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952
+ K + +GEG G+V + T+ + VA+K + + + EI I++
Sbjct 200 PTKIYKNMTKIGEGAAGEV----FVATSSKNNKRVAIKKI--EINNDNAKLLVTEIAIMK 253
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICE 1009
T +H++I+ Y ++ L + ME++ G L D L + Q+ ++ +
Sbjct 254 TSHHDNIVNYIDSYIV-NDRELWVAMEFMGGGCLTDILEAFDNIKMSEIQIAYVVKETLK 312
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069
+ Y+H+ H IHRD+ + N+LL ++ VKI DFG A + + + R +W A
Sbjct 313 ALQYIHSLHRIHRDIKSDNILLGSEGSVKIADFGYAAQLTQ---KQQKRNTVVGTPYWMA 369
Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129
PE ++ + + D+WS G+ + E+ P + +G + T
Sbjct 370 PELIRGHDYGVKVDIWSLGIMMMEMAEGEPPYMDFPPLRALFLITTKGIPPLKETT---- 425
Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
K C + + RP +L+
Sbjct 426 ---------KWSKTFQDFFSKCLDINVANRPDATDLLK 454
Score = 177 bits (449), Expect = 3e-46, Method: Composition-based stats.
Identities = 68/409 (17%), Positives = 129/409 (32%), Gaps = 46/409 (11%)
Query 470 LYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVREL 529
++ + + V + S+ Q L+ + A G + + + +
Sbjct 86 FFIQANTPDEMASWMKAVEKGSEYSTVSQPFNLKHEVHVDFNSATGFSGLPKEWEVILKS 145
Query 530 GAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEI 589
+ +L + S+ + E SN + A L LS L K
Sbjct 146 SNVSKQEVLDKPSEWLSVLEFQAGRTMEKSNSQNL-SALPDESNLTLSDLVTKEDPTKIY 204
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
++ +G+G V+ RV +K ++ ++
Sbjct 205 KNMTKIGEGAAGEVF------------------------VATSSKNNKRVAIKKIEINN- 239
Query 650 DIALAFYETASLMSQVSHTHLAFVHG-VCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVP 707
D A ++M H ++ V E + E++ G L L + +
Sbjct 240 DNAKLLVTEIAIMKTSHHDNIVNYIDSYIVNDRELWVAMEFMGGGCLTDILEAFDNIKMS 299
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
V ++ AL Y+ + + +H ++ NILL G+ +K++D G
Sbjct 300 EIQIAYVVKETLKALQYIHSLHRIHRDIKSDNILL-------GSEGSVKIADFGYAAQLT 352
Query 768 ----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823
R V W+APE + G + +D W G ++E+ +GE P P
Sbjct 353 QKQQKRNTVVGTPYWMAPELIRG--HDYGVKVDIWSLGIMMMEMA-EGEPPYMDFPPLRA 409
Query 824 EHFYQRQHRLP----EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868
+ P S+CL RP +L+
Sbjct 410 LFLITTKGIPPLKETTKWSKTFQDFFSKCLDINVANRPDATDLLKHPFM 458
>sp|Q54XZ5|Y0138_DICDI Probable serine/threonine-protein kinase
DDB_G0278509 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0278509
PE=3 SV=1
Length=1248
Score = 220 bits (561), Expect = 3e-57, Method: Composition-based stats.
Identities = 79/356 (22%), Positives = 136/356 (38%), Gaps = 65/356 (18%)
Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919
R Q + + ++ +G+G F KV +
Sbjct 909 RQSSFQQIPQQFNLSTSTTNITKLPRIKYTWEIDFDEIQFFNLIGQGGFSKVYHGVWRSK 968
Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY-HEHIIKYKGCCEDQGEKSLQLVM 978
+ VA+K ++ + +++E+ IL L HE+++ Y G C + ++
Sbjct 969 D------VAIKQIELQNN-KSLDDFRREVGILSKLKPHENLLAYYGAC--KHANYCYIIT 1019
Query 979 EYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLH--AQHYIHRDLAARNVLLDN 1033
EY+P GSL D L R + Q + FA + G +L H DL +N+L+ N
Sbjct 1020 EYLPRGSLHDLLHREQLMKLDFKQKVSFAICVALGCYHLSTYEPPIYHTDLKTKNLLVTN 1079
Query 1034 DRLVKIGDFGLAKAVPEG-----------------------------------HEYYRVR 1058
+KI DFGLA + + V
Sbjct 1080 ALKIKIADFGLASFAKKSLTTIINNNNNTNNTATSSTTTSSANGANSISNNNNNGTTSVD 1139
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
+ + F+ APE L F SDV+SFG L+EL+T+
Sbjct 1140 QSRLAYAFYAAPEILNSKHFSEKSDVFSFGTILWELVTNKIPFD---------------G 1184
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174
M + ELL+ G+RL P+ C + +++++CW ++ RPTF ++ L+ + +
Sbjct 1185 MDPYEVKELLKSGKRLEIPENCNEVLKNIIQDCWNQQSEDRPTFLSIYHRLENLMK 1240
Score = 185 bits (469), Expect = 4e-46, Method: Composition-based stats.
Identities = 70/367 (19%), Positives = 124/367 (34%), Gaps = 88/367 (24%)
Query 556 GETSNLIIMRGARASPRTLNLSQLS----FHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611
++S I + S T N+++L +D EI + +GQG + VY G R +
Sbjct 909 RQSSFQQIPQQFNLSTSTTNITKLPRIKYTWEIDFDEIQFFNLIGQGGFSKVYHGVWRSK 968
Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS-HTHL 670
V +K ++ ++ F ++S++ H +L
Sbjct 969 D--------------------------VAIKQIELQNNKSLDDFRREVGILSKLKPHENL 1002
Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLE--N 727
+G C ++TEY+ G L L RE+ + K+ A +A +L
Sbjct 1003 LAYYGACKHANYCYIITEYLPRGSLHDLLHREQLMKLDFKQKVSFAICVALGCYHLSTYE 1062
Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS------------------- 768
+ H ++ +N+L+ + IK++D G+ A
Sbjct 1063 PPIYHTDLKTKNLLVTN-------ALKIKIADFGLASFAKKSLTTIINNNNNTNNTATSS 1115
Query 769 -----------------------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805
+ R+ + APE L + S D + FG L
Sbjct 1116 TTTSSANGANSISNNNNNGTTSVDQSRLAYAFYAAPEIL--NSKHFSEKSDVFSFGTILW 1173
Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
E+ + + P P E + + RL PE L + C + RP+F +I
Sbjct 1174 ELVTN-KIPFDGMDPYEVKELLKSGKRLEIPENCNEVLKNIIQDCWNQQSEDRPTFLSIY 1232
Query 864 RDLTRLQ 870
L L
Sbjct 1233 HRLENLM 1239
>sp|O14427|CLA4_CANAX Serine/threonine-protein kinase CLA4 OS=Candida
albicans OX=5476 GN=CLA4 PE=3 SV=1
Length=971
Score = 219 bits (557), Expect = 3e-57, Method: Composition-based stats.
Identities = 62/268 (23%), Positives = 112/268 (42%), Gaps = 23/268 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
G+G G V L +A+K + D P+ + EI +++ H++I+
Sbjct 685 KAGQGASGNVYLAE---MIKDNNRKIAIKQMDLDAQPR-KELIINEILVMKDSQHKNIVN 740
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G+ L ++MEY+ GSL + + + + Q+ + +G+ +LH +H
Sbjct 741 FLDSYLI-GDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIATICFETLKGLQHLHKKHI 799
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ + NVLLD VKI DFG + + R +W APE +K+ ++
Sbjct 800 IHRDIKSDNVLLDAYGNVKITDFGFCAKLTDQRN---KRATMVGTPYWMAPEVVKQKEYD 856
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
DVWS G+ E++ PP E + T +L +P+
Sbjct 857 EKVDVWSLGIMTIEMI-----EGEPPYLNEEPLKALYLIATNGT--------PKLKKPEL 903
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + C + +R + + L+
Sbjct 904 LSNSIKKFLSICLCVDVRYRASTDELLE 931
Score = 189 bits (481), Expect = 6e-48, Method: Composition-based stats.
Identities = 57/346 (16%), Positives = 104/346 (30%), Gaps = 62/346 (18%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHL----------------- 595
P P + SN + + T QL R ++ ++ L
Sbjct 626 PSPTDKSNKPTAPASGPA-VTKTAKQLKKERERLNDLQIIAKLKTVVNNQDPKPLFRIVE 684
Query 596 --GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
GQG NVY + + ++ +K +D
Sbjct 685 KAGQGASGNVY-----------------------LAEMIKDNNRKIAIKQMDLDAQPRKE 721
Query 654 AFYETASLMSQVSHTHLAFVHG-VCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
+M H ++ + E ++ EY++ G L + +
Sbjct 722 LIINEILVMKDSQHKNIVNFLDSYLIGDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIA 781
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS---- 768
+ + L +L K+++H ++ N+LL G +K++D G
Sbjct 782 TICFETLKGLQHLHKKHIIHRDIKSDNVLLDAYG-------NVKITDFGFCAKLTDQRNK 834
Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
R V W+APE + +D W G +E+ +GE P + P + +
Sbjct 835 RATMVGTPYWMAPEVVKQ--KEYDEKVDVWSLGIMTIEMI-EGEPPYLNEEPLKALYLIA 891
Query 829 RQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
PE + S CL + R S +L
Sbjct 892 TNGTPKLKKPELLSNSIKKFLSICLCVDVRYRASTDELLEHSFIQH 937
>sp|Q39026|MPK6_ARATH Mitogen-activated protein kinase 6 OS=Arabidopsis
thaliana OX=3702 GN=MPK6 PE=1 SV=1
Length=395
Score = 206 bits (525), Expect = 3e-57, Method: Composition-based stats.
Identities = 71/318 (22%), Positives = 115/318 (36%), Gaps = 31/318 (10%)
Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCG 937
+ + +Y I +G+G +G V N T E VA+K + A
Sbjct 45 RFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVC----SAMNSETNESVAIKKIANAFDN 100
Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGSLRDYLP-RH 993
+EI +LR + HE+I+ + + + E + L +
Sbjct 101 KIDAKRTLREIKLLRHMDHENIVAIRDIIPPPLRNAFNDVYIAYELMD-TDLHQIIRSNQ 159
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
++ F QI G+ Y+H+ + +HRDL N+LL+ + +KI DFGLA+ E
Sbjct 160 ALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSESD- 218
Query 1054 YYRVREDGDSPVFWYAPE-CLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTK 1107
+ ++ APE L + A DVWS G EL+
Sbjct 219 ---FMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRL 275
Query 1108 FLELIGIA------QGQMTVLRLTELLERGERLPRPDKCP---CEVYHLMKNCWETEASF 1158
+ELIG R L R DK P L++ +
Sbjct 276 LMELIGTPSEEELEFLNENAKRYIRQLPPYPRQSITDKFPTVHPLAIDLIEKMLTFDPRR 335
Query 1159 RPTFENLI--PILKTVHE 1174
R T + + P L ++H+
Sbjct 336 RITVLDALAHPYLNSLHD 353
Score = 127 bits (319), Expect = 5e-30, Method: Composition-based stats.
Identities = 33/221 (15%), Positives = 75/221 (34%), Gaps = 26/221 (12%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF--YE 657
N++E + + + + V +K + + + A
Sbjct 52 FGNIFE--VTAKYKPPIMPIGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAKRTLR 109
Query 658 TASLMSQVSHTHLAFVHGVCVRGPEN-------IMVTEYVEHGPLDVWLRRERGHVPMAW 710
L+ + H ++ + + P + E ++ L +R + +
Sbjct 110 EIKLLRHMDHENIVAIRDII--PPPLRNAFNDVYIAYELMD-TDLHQIIRSNQA-LSEEH 165
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
Q+ L Y+ + N++H ++ N+LL + +K+ D G+ +
Sbjct 166 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLN-------ANCDLKICDFGLARVTSESD 218
Query 771 ---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
E V + APE L ++ + A+D W G +E+
Sbjct 219 FMTEYVVTRWYRAPELLLN-SSDYTAAIDVWSVGCIFMELM 258
>sp|Q5APR8|CLA4_CANAL Serine/threonine-protein kinase CLA4 OS=Candida
albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=CLA4
PE=1 SV=1
Length=976
Score = 219 bits (557), Expect = 3e-57, Method: Composition-based stats.
Identities = 62/268 (23%), Positives = 112/268 (42%), Gaps = 23/268 (9%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961
G+G G V L +A+K + D P+ + EI +++ H++I+
Sbjct 690 KAGQGASGNVYLAE---MIKDNNRKIAIKQMDLDAQPR-KELIINEILVMKDSQHKNIVN 745
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ G+ L ++MEY+ GSL + + + + Q+ + +G+ +LH +H
Sbjct 746 FLDSYLI-GDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIATICFETLKGLQHLHKKHI 804
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
IHRD+ + NVLLD VKI DFG + + R +W APE +K+ ++
Sbjct 805 IHRDIKSDNVLLDAYGNVKITDFGFCAKLTDQRN---KRATMVGTPYWMAPEVVKQKEYD 861
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
DVWS G+ E++ PP E + T +L +P+
Sbjct 862 EKVDVWSLGIMTIEMI-----EGEPPYLNEEPLKALYLIATNGT--------PKLKKPEL 908
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + C + +R + + L+
Sbjct 909 LSNSIKKFLSICLCVDVRYRASTDELLE 936
Score = 189 bits (481), Expect = 7e-48, Method: Composition-based stats.
Identities = 57/346 (16%), Positives = 104/346 (30%), Gaps = 62/346 (18%)
Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHL----------------- 595
P P + SN + + T QL R ++ ++ L
Sbjct 631 PSPTDKSNKPTAPASGPA-VTKTAKQLKKERERLNDLQIIAKLKTVVNNQDPKPLFRIVE 689
Query 596 --GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
GQG NVY + + ++ +K +D
Sbjct 690 KAGQGASGNVY-----------------------LAEMIKDNNRKIAIKQMDLDAQPRKE 726
Query 654 AFYETASLMSQVSHTHLAFVHG-VCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712
+M H ++ + E ++ EY++ G L + +
Sbjct 727 LIINEILVMKDSQHKNIVNFLDSYLIGDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIA 786
Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS---- 768
+ + L +L K+++H ++ N+LL G +K++D G
Sbjct 787 TICFETLKGLQHLHKKHIIHRDIKSDNVLLDAYG-------NVKITDFGFCAKLTDQRNK 839
Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828
R V W+APE + +D W G +E+ +GE P + P + +
Sbjct 840 RATMVGTPYWMAPEVVKQ--KEYDEKVDVWSLGIMTIEMI-EGEPPYLNEEPLKALYLIA 896
Query 829 RQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870
PE + S CL + R S +L
Sbjct 897 TNGTPKLKKPELLSNSIKKFLSICLCVDVRYRASTDELLEHSFIQH 942
>sp|Q9CAU7|NEK2_ARATH Serine/threonine-protein kinase Nek2 OS=Arabidopsis
thaliana OX=3702 GN=NEK2 PE=2 SV=1
Length=606
Score = 213 bits (541), Expect = 3e-57, Method: Composition-based stats.
Identities = 63/293 (22%), Positives = 124/293 (42%), Gaps = 34/293 (12%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961
+G+G FG L + ++ +K ++ A + R QE++++ +++ I++
Sbjct 10 IGKGSFGSALLV----RHKHEKKLYVLKKIRLARQTGRTRRSAHQEMELISKIHNPFIVE 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018
YK ++G + +++ Y G + + + + + +L + QI + YLHA H
Sbjct 66 YKDSWVEKG-CYVCIIIGYCKGGDMAEAIKKTNGVHFTEEKLCKWLVQILLALEYLHANH 124
Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078
+HRD+ N+ L D+ +++GDFGLAK + + + PE L + +
Sbjct 125 ILHRDVKCSNIFLTKDQDIRLGDFGLAKVLTSDD----LASSVVGTPSYMCPELLADIPY 180
Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138
SD+WS G +YE+ ++ P K ++ G L + R P P
Sbjct 181 GSKSDIWSLGCCMYEM-----TAMKPAFKAFDMQG----------LINRINRSIVPPLPA 225
Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLI------PILKTVHEKYQGQAPSVFS 1185
+ L+K+ RP+ L+ P ++ +H K +V
Sbjct 226 QYSAAFRGLVKSMLRKNPELRPSAAELLRQPLLQPYIQKIHLKVNDPGSNVLP 278
Score = 139 bits (351), Expect = 7e-33, Method: Composition-based stats.
Identities = 50/290 (17%), Positives = 91/290 (31%), Gaps = 43/290 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VL 644
+ L +G+G+ + R + E ++L V+ K L
Sbjct 1 MENYEVLEQIGKGSFGSALLVRHKHE-----------------------KKLYVLKKIRL 37
Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRER 703
+ ++ L+S++ + + V ++ Y + G + +++
Sbjct 38 ARQTGRTRRSAHQEMELISKIHNPFIVEYKDSWVEKGCYVCIIIGYCKGGDMAEAIKKTN 97
Query 704 G-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
G H Q+ AL YL +++H +V NI L + I+L D G+
Sbjct 98 GVHFTEEKLCKWLVQILLALEYLHANHILHRDVKCSNIFLTK-------DQDIRLGDFGL 150
Query 763 GLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
S + V ++ PE L + D W G + E+ P
Sbjct 151 AKVLTSDDLASSVVGTPSYMCPELLAD--IPYGSKSDIWSLGCCMYEM--TAMKPAFKAF 206
Query 820 PSEKEHFYQRQ---HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866
+ + LP L L P RPS +LR
Sbjct 207 DMQGLINRINRSIVPPLPAQYSAAFRGLVKSMLRKNPELRPSAAELLRQP 256
>sp|Q9QYZ3|SMK2B_MOUSE Sperm motility kinase 2B OS=Mus musculus
OX=10090 GN=Smok2b PE=1 SV=1
Length=484
Score = 209 bits (532), Expect = 3e-57, Method: Composition-based stats.
Identities = 63/279 (23%), Positives = 104/279 (37%), Gaps = 30/279 (11%)
Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949
+ +G G KV L + TG VAVK ++ + E++
Sbjct 1 MENFHAQYVMLETIGHGGCSKVML----ARHRLTGSHVAVKMIRK--SECWCNPVMSEVE 54
Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQIC 1008
+L H +II E + K + L+ME SL ++ + + +Q+
Sbjct 55 LLMMADHPNIISLLQVIETK--KKVYLIMELCEGKSLYQHIRNAGYLQEDEARALFKQLL 112
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
M Y H Q +HRDL N++++ D VKI DFGL V G + +
Sbjct 113 SAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLGTQVKPGQKL----NLFCGTYPFS 168
Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
APE L + DVW+ GV LY ++T + ++ +L
Sbjct 169 APEVLLSRPYDGPKIDVWTLGVVLYFMVTGKVPFDAA---------------SIQKLVRQ 213
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166
+ G+ P + E+ L+ RPT ++
Sbjct 214 ILAGKYF-VPSRLSVELRDLISLLMTANPKLRPTVAEVM 251
Score = 167 bits (423), Expect = 7e-43, Method: Composition-based stats.
Identities = 55/306 (18%), Positives = 105/306 (34%), Gaps = 39/306 (13%)
Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647
+ L +G G + V R R+ GS V +K++ S
Sbjct 7 QYVMLETIGHGGCSKVMLARHRLTGS------------------------HVAVKMIRKS 42
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
L+ H ++ + V + ++ E E L +R G++
Sbjct 43 EC-WCNPVMSEVELLMMADHPNIISLLQVIETKKKVYLIMELCEGKSLYQHIRNA-GYLQ 100
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
+ +QL SA++Y N+ +VH ++ NI++ + G +K+ D G+G
Sbjct 101 EDEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDG-------KVKIIDFGLGTQVK 153
Query 768 SREE---RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE-K 823
++ P+ APE L +D W G L + G+ P + S +
Sbjct 154 PGQKLNLFCGTYPFSAPEVLLSRPYD-GPKIDVWTLGVVLYFMV-TGKVPFDAASIQKLV 211
Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
++ +P +L L S +T P RP+ ++ + +
Sbjct 212 RQILAGKYFVPSRLSVELRDLISLLMTANPKLRPTVAEVMVHPWVTEGSGVFPDPCEEQM 271
Query 884 SPASDP 889
+P
Sbjct 272 PLKPNP 277
>sp|P67998|KS6B1_RABIT Ribosomal protein S6 kinase beta-1 OS=Oryctolagus
cuniculus OX=9986 GN=RPS6KB1 PE=2 SV=1
Length=525
Score = 210 bits (535), Expect = 3e-57, Method: Composition-based stats.
Identities = 70/292 (24%), Positives = 115/292 (39%), Gaps = 26/292 (9%)
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931
+ ++ S P + +R LG+G +GKV T TG++ A+K
Sbjct 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKV 124
Query 932 LKADC---GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
LK + + K E +IL + H I+ + G+ L L++EY+ G L
Sbjct 125 LKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGK--LYLILEYLSGGELFM 182
Query 989 YLPRHSIG-LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
L R I + +I + +LH + I+RDL N++L++ VK+ DFGL K
Sbjct 183 QLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK- 241
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
E V + + APE L A D WS G +Y++LT
Sbjct 242 --ESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTG---- 295
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+ T+ ++ + +L P E L+K + A+ R
Sbjct 296 -------ENRKKTIDKILKC-----KLNLPPYLTQEARDLLKKLLKRNAASR 335
Score = 154 bits (390), Expect = 3e-38, Method: Composition-based stats.
Identities = 52/280 (19%), Positives = 99/280 (35%), Gaps = 33/280 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
++ + L LG+G V++ R +V G+ + M + R+
Sbjct 84 EKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKVLKKAMIVRNAK------- 135
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
D +H E H + + G + ++ EY+ G L + L R
Sbjct 136 ---DTAHTKAERNILEEV------KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER 186
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
E G +++ AL +L K +++ ++ NI+L G +KL+D G
Sbjct 187 E-GIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-------HVKLTDFG 238
Query 762 VGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ ++ I ++APE L + + A+D W GA + ++ G P
Sbjct 239 LCKESIHDGTVTHTFCGTIEYMAPEILM--RSGHNRAVDWWSLGALMYDML-TGAPPFTG 295
Query 818 RSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQR 856
+ + + LP + L + L R
Sbjct 296 ENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASR 335
>sp|P32491|MKK2_YEAST MAP kinase kinase MKK2/SSP33 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MKK2
PE=1 SV=2
Length=506
Score = 210 bits (534), Expect = 4e-57, Method: Composition-based stats.
Identities = 82/392 (21%), Positives = 155/392 (40%), Gaps = 24/392 (6%)
Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL 841
E G + LS T E+ AP+ ++ + F ++ PE
Sbjct 104 EYRVAGDSQLSERFSNLHVDITYKELLSS--APISTKLSNIDTTFIKKDLDTPEGEDSYP 161
Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901
+TL S Y+ + S L + NL V+ + K + +
Sbjct 162 STLLSA---YDFSSSGSNSAPLSANNIISCSNLIQGKDVDQLEEEAWRFGHLKDEITTLG 218
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHII 960
LGEG G V+ ++ A+K + + P+++ +E+ ++ ++I+
Sbjct 219 ILGEGAGGSVA----KCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIV 274
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSL----RDYLPRH-SIGLAQLLLFAQQICEGMAYLH 1015
+Y G D+ S+ + MEY+ SL ++ L R I + A+ + G++YLH
Sbjct 275 QYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLH 334
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+ IHRD+ +N+LL+ +K+ DFG++ G + F+ APE ++
Sbjct 335 ERKVIHRDIKPQNILLNEKGEIKLCDFGVS-----GEAVNSLAMTFTGTSFYMAPERIQG 389
Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135
+ DVWS G+TL E+ +S K + + + +L + L+ L
Sbjct 390 QPYSVTCDVWSLGLTLLEVAGGRFPFES--DKITQNVAPIELLTMILTFSPQLKDEPELD 447
Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ C + +A RP+ ++
Sbjct 448 I--SWSKTFRSFIDYCLKKDARERPSPRQMLK 477
Score = 169 bits (428), Expect = 2e-43, Method: Composition-based stats.
Identities = 61/322 (19%), Positives = 105/322 (33%), Gaps = 56/322 (17%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ EIT L LG+G +V + RL+ LK ++
Sbjct 211 KDEITTLGILGEGAGGSVAKCRLKNGKKVF------------------------ALKTIN 246
Query 646 --PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG--PENIMVTEYVEHGPL---DVW 698
+ + + ++ +G+ + EY+ L
Sbjct 247 TMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKN 306
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
L + G + +A+ + LSYL + ++H ++ +NILL G IKL
Sbjct 307 LLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGE-------IKLC 359
Query 759 DPGVGLGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL- 815
D GV A++ ++APE + G S D W G TLLE+ G P
Sbjct 360 DFGVSGEAVNSLAMTFTGTSFYMAPERIQG--QPYSVTCDVWSLGLTLLEVA-GGRFPFE 416
Query 816 -----QSRSPSEKEHFY-------QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863
Q+ +P E + + L + CL + +RPS R +L
Sbjct 417 SDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQML 476
Query 864 RDLTRLQPHNLADVLTVNPDSP 885
+ + +
Sbjct 477 KHPWIVGQMKKKVNMERFVKKC 498
>sp|Q8C0X8|SMKX_MOUSE Sperm motility kinase X OS=Mus musculus
OX=10090 PE=2 SV=1
Length=640
Score = 213 bits (542), Expect = 4e-57, Method: Composition-based stats.
Identities = 65/272 (24%), Positives = 113/272 (42%), Gaps = 31/272 (11%)
Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955
+ + + LG+G FG+V L ++ T VA+K L EI+I+++L
Sbjct 23 HYEILTTLGQGTFGEVKL----ASHLVTQTKVAIKILPKSRKNSLVQP---EIEIMKSLD 75
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYL 1014
H HIIK +++ +V+E+ G L + + + +Q+ + Y
Sbjct 76 HPHIIKLLHII--DTTRNIFIVLEHAVGGELMSRIEEFGYLAEVECHRLFKQLVYALQYC 133
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H + +HRDL N+LLD+ VK+ DFGL + G + + + APE +
Sbjct 134 HEKGIVHRDLKPENILLDHRGNVKLTDFGLGTKIIMGQKLVT----FCGTLPYCAPELFE 189
Query 1075 EYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133
+ + A+DVWS GV LY + T C + ++ IA +
Sbjct 190 DRGYDGRATDVWSLGVVLYFMATGCLPFNGYSYEAIKQKIIA----------------GK 233
Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165
PR E++ ++ RPT ++
Sbjct 234 YPRSFSLSPELWEVIAKLLTVNPGERPTVHDI 265
Score = 175 bits (444), Expect = 1e-44, Method: Composition-based stats.
Identities = 58/285 (20%), Positives = 100/285 (35%), Gaps = 38/285 (13%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
+ L+ LGQGT V + +V +K+L
Sbjct 21 TEHYEILTTLGQGTFGEV------------------------KLASHLVTQTKVAIKILP 56
Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705
S + + +M + H H+ + + +V E+ G L + E G+
Sbjct 57 KSRKNSLVQ--PEIEIMKSLDHPHIIKLLHIIDTTRNIFIVLEHAVGGELMSRI-EEFGY 113
Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765
+ + +QL AL Y K +VH ++ NILL G +KL+D G+G
Sbjct 114 LAEVECHRLFKQLVYALQYCHEKGIVHRDLKPENILLDHRG-------NVKLTDFGLGTK 166
Query 766 ALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822
+ ++ V +P+ APE A D W G L + +
Sbjct 167 IIMGQKLVTFCGTLPYCAPELFEDRGYD-GRATDVWSLGVVLYFMATGCLPFNGYSYEAI 225
Query 823 KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
K+ ++ P+L + ++ LT P +RP+ I R
Sbjct 226 KQKIIAGKYPRSFSLSPELWEVIAKLLTVNPGERPTVHDIARFKW 270
>sp|Q9P419|HOG1_EMENI Mitogen-activated protein kinase hog1 OS=Emericella
nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46
/ NRRL 194 / M139) OX=227321 GN=hog1 PE=1 SV=1
Length=379
Score = 206 bits (523), Expect = 4e-57, Method: Composition-based stats.
Identities = 70/294 (24%), Positives = 110/294 (37%), Gaps = 43/294 (15%)
Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959
+ +G G FG V + T + VAVK + K P +E+ +L+ L HE+I
Sbjct 24 QPVGMGAFGLVC----SARDQLTAQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79
Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
I E + V E + L + + + F QI G+ Y+H+
Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLISSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078
+HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+
Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191
Query 1079 YYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGIAQGQMTVL 1122
DVWS E+L +PP ++ I V
Sbjct 192 DAKVDVWSAACIFAEMLLGAPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVK 251
Query 1123 RLTELLERGE-RLPR------PDKCPCE------VYHLMKNCWETEASFRPTFE 1163
L + + +LP+ PDK P E +L+K R + E
Sbjct 252 SLPKREPQDLAKLPKFLALVHPDKKPEEDEDYKNTINLLKAMLVYNPKDRISAE 305
Score = 132 bits (332), Expect = 7e-32, Method: Composition-based stats.
Identities = 46/334 (14%), Positives = 96/334 (29%), Gaps = 23/334 (7%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
+E R G + RD+ V +K ++ P ++ Y
Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSARDQLTAQPVAVKKIMKPFSTPVLSKRTYR 66
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H ++ + + + + VTE + L + + +
Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLISSR--PLEKQFIQYFLY 123
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V
Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835
+ APE + +D W E+ ++ + P+
Sbjct 177 RYYRAPE-IMLTWQKYDAKVDVWSAACIFAEMLLGAPLFPGKDHVNQFSIITELLGTPPD 235
Query 836 PSCPQLA-TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894
+ T + + P + P L L + + + +
Sbjct 236 DVIQTICSENTLRFVKSLPKREPQDLAKLPKFLALVHPDKKPEEDEDYKNTINLLKAMLV 295
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928
K ++ P +D T E VA
Sbjct 296 YNPKDRISAEA----ALAAPYLAPYHDETDEPVA 325
>sp|P21708|MK03_RAT Mitogen-activated protein kinase 3 OS=Rattus
norvegicus OX=10116 GN=Mapk3 PE=1 SV=5
Length=380
Score = 206 bits (523), Expect = 4e-57, Method: Composition-based stats.
Identities = 62/301 (21%), Positives = 119/301 (40%), Gaps = 26/301 (9%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+++ +GEG +G VS + VA+K + + +EI IL
Sbjct 41 PRYTQLQYIGEGAYGMVS----SAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRF 96
Query 955 YHEHIIKYKGCCEDQG---EKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011
HE++I + + + +V + + L L + + F QI G+
Sbjct 97 RHENVIGIRDILRAPTLEAMRDVYIVQDLME-TDLYKLLKSQQLSNDHICYFLYQILRGL 155
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
Y+H+ + +HRDL N+L++ +KI DFGLA+ H++ + + ++ APE
Sbjct 156 KYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPE 215
Query 1072 C-LKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGI--AQGQMTVLRLTE 1126
L + + D+WS G L E+L++ + + ++GI + Q + +
Sbjct 216 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 275
Query 1127 LLERGERLPRP-----------DKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVH 1173
+ R P K + L+ + R T E + P L+ +
Sbjct 276 MKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYY 335
Query 1174 E 1174
+
Sbjct 336 D 336
Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats.
Identities = 38/250 (15%), Positives = 82/250 (33%), Gaps = 48/250 (19%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
TQL ++G+G V D ++ RV +K + P H
Sbjct 44 TQLQYIGEGAYGMV------------------------SSAYDHVRKTRVAIKKISPFEH 79
Query 650 DIA-LAFYETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDVWLRRER 703
++ + H ++ + + + +V + +E L L+ +
Sbjct 80 QTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLME-TDLYKLLKSQ- 137
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ Q+ L Y+ + N++H ++ N+L+ T+ +K+ D G+
Sbjct 138 -QLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLIN-------TTCDLKICDFGLA 189
Query 764 LGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
A + + APE + + + ++D W G L E+ +
Sbjct 190 RIADPEHDHTGFLTEYVATRWYRAPE-IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPG 248
Query 817 SRSPSEKEHF 826
+ H
Sbjct 249 KHYLDQLNHI 258
>sp|Q63844|MK03_MOUSE Mitogen-activated protein kinase 3 OS=Mus
musculus OX=10090 GN=Mapk3 PE=1 SV=5
Length=380
Score = 206 bits (523), Expect = 4e-57, Method: Composition-based stats.
Identities = 62/301 (21%), Positives = 119/301 (40%), Gaps = 26/301 (9%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+++ +GEG +G VS + VA+K + + +EI IL
Sbjct 41 PRYTQLQYIGEGAYGMVS----SAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRF 96
Query 955 YHEHIIKYKGCCEDQG---EKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011
HE++I + + + +V + + L L + + F QI G+
Sbjct 97 RHENVIGIRDILRAPTLEAMRDVYIVQDLME-TDLYKLLKSQQLSNDHICYFLYQILRGL 155
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
Y+H+ + +HRDL N+L++ +KI DFGLA+ H++ + + ++ APE
Sbjct 156 KYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPE 215
Query 1072 C-LKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGI--AQGQMTVLRLTE 1126
L + + D+WS G L E+L++ + + ++GI + Q + +
Sbjct 216 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 275
Query 1127 LLERGERLPRP-----------DKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVH 1173
+ R P K + L+ + R T E + P L+ +
Sbjct 276 MKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYY 335
Query 1174 E 1174
+
Sbjct 336 D 336
Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats.
Identities = 38/250 (15%), Positives = 82/250 (33%), Gaps = 48/250 (19%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
TQL ++G+G V D ++ RV +K + P H
Sbjct 44 TQLQYIGEGAYGMV------------------------SSAYDHVRKTRVAIKKISPFEH 79
Query 650 DIA-LAFYETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDVWLRRER 703
++ + H ++ + + + +V + +E L L+ +
Sbjct 80 QTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLME-TDLYKLLKSQ- 137
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ Q+ L Y+ + N++H ++ N+L+ T+ +K+ D G+
Sbjct 138 -QLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLIN-------TTCDLKICDFGLA 189
Query 764 LGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
A + + APE + + + ++D W G L E+ +
Sbjct 190 RIADPEHDHTGFLTEYVATRWYRAPE-IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPG 248
Query 817 SRSPSEKEHF 826
+ H
Sbjct 249 KHYLDQLNHI 258
>sp|P24033|CDK1B_XENLA Cyclin-dependent kinase 1-B OS=Xenopus
laevis OX=8355 GN=cdk1-b PE=1 SV=2
Length=302
Score = 203 bits (516), Expect = 4e-57, Method: Composition-based stats.
Identities = 64/302 (21%), Positives = 117/302 (39%), Gaps = 31/302 (10%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+
Sbjct 1 MDEYTKIEKIGEGTYGVV----YKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQIC 1008
L H +I+ + L L+ E++ + L+ YL I + + QI
Sbjct 57 ELQHPNIVCLLDVLMQ--DSRLYLIFEFLSM-DLKKYLDSIPSGQYIDTMLVKSYLYQIL 113
Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
+G+ + H++ +HRDL +N+L+DN ++K+ DFGLA+A RV +++
Sbjct 114 QGIVFCHSRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGIP---VRVYTHEVVTLWYR 170
Query 1069 APECLKEY-KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127
A E L ++ DVWS G E+ T +
Sbjct 171 ASEVLLGSVRYSTPVDVWSVGTIFAEIATKKPLFHGDSEIDQLFRIFRSLGTPNNEVWPE 230
Query 1128 LE--RGERLPRP-----------DKCPCEVYHLMKNCWETEASFRPTFEN--LIPILKTV 1172
+E + + P + L+ + + R + L P +
Sbjct 231 VESLQDYKNTFPKWKGGSLSSNVKNIDEDGLDLLSKMLVYDPAKRISARKAMLHPYFDDL 290
Query 1173 HE 1174
+
Sbjct 291 DK 292
Score = 164 bits (414), Expect = 2e-43, Method: Composition-based stats.
Identities = 44/267 (16%), Positives = 93/267 (35%), Gaps = 41/267 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
E T++ +G+GT VY+GR + G V +K
Sbjct 1 MDEYTKIEKIGEGTYGVVYKGRHKATGQ------------------------VVAMKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-- 701
L+ + SL+ ++ H ++ + V ++ ++ E++ L +L
Sbjct 37 LENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
++ Q+ + + ++ ++H ++ +N+L+ G+ IKL+D G
Sbjct 96 SGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDNKGV-------IKLADFG 148
Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ V + + A E L G+ ST +D W G EI
Sbjct 149 LARAFGIPVRVYTHEVVTLWYRASEVLL-GSVRYSTPVDVWSVGTIFAEIATKKPLFHGD 207
Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ P++ +L
Sbjct 208 SEIDQLFRIFRSLGTPNNEVWPEVESL 234
>sp|P53351|PLK2_MOUSE Serine/threonine-protein kinase PLK2 OS=Mus
musculus OX=10090 GN=Plk2 PE=1 SV=1
Length=682
Score = 214 bits (545), Expect = 4e-57, Method: Composition-based stats.
Identities = 73/320 (23%), Positives = 132/320 (41%), Gaps = 28/320 (9%)
Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909
P Q +T PH+ P+ + + + LG+G F
Sbjct 32 KKRPQQPSEDGQPQAQVTPAAPHHHHHHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFA 91
Query 910 KVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967
K CY+ T+ ++ A K + P R +EI++ R L+H+H++++ E
Sbjct 92 K----CYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHKHVVQFYHYFE 147
Query 968 DQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026
D+ +++ +++EY S+ L R + ++ + +QI G+ YLH Q +HRDL
Sbjct 148 DK--ENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKL 205
Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086
N ++ +K+GDFGLA + +R R +P + +PE L + SD+W+
Sbjct 206 GNFFINEAMELKVGDFGLAARLEPLE--HRRRTICGTPN-YLSPEVLNKQGHGCESDIWA 262
Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146
G +Y +L ++ T L+ T R R P H
Sbjct 263 LGCVMYTMLLGRPPFET----------------TNLKETYRCIREARYTMPSSLLAPAKH 306
Query 1147 LMKNCWETEASFRPTFENLI 1166
L+ + RP+ +++I
Sbjct 307 LIASMLSKNPEDRPSLDDII 326
Score = 154 bits (388), Expect = 3e-37, Method: Composition-based stats.
Identities = 52/341 (15%), Positives = 101/341 (30%), Gaps = 38/341 (11%)
Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650
+ LG+G YE + + K+ + R
Sbjct 81 RGKVLGKGGFAKCYE--MTDLTNNKVYAAKIIPHSRVAKPHQR----------------- 121
Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710
+ L + H H+ + ++ EY + L+ R +
Sbjct 122 --EKIDKEIELHRLLHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKA-RKVLTEPE 178
Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770
+Q+ S L YL + ++H ++ N + + +K+ D G+ E
Sbjct 179 VRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINE-------AMELKVGDFGLAARLEPLE 231
Query 771 ER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH- 825
R +L+PE L D W G + + G P ++ + E
Sbjct 232 HRRRTICGTPNYLSPEVL--NKQGHGCESDIWALGCVMYTMLL-GRPPFETTNLKETYRC 288
Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885
+ ++ +P L + L+ P RPS I+R LQ + + +
Sbjct 289 IREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTV 348
Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926
+ K GK Y+ T++ +
Sbjct 349 PDFHLSSPAKNFFKKAAAALFG-GKKDKARYNDTHNKVSKE 388
>sp|Q5BBL3|STE20_EMENI Serine/threonine-protein kinase ste20 OS=Emericella
nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46
/ NRRL 194 / M139) OX=227321 GN=ste20 PE=3 SV=1
Length=848
Score = 217 bits (552), Expect = 4e-57, Method: Composition-based stats.
Identities = 56/271 (21%), Positives = 110/271 (41%), Gaps = 23/271 (8%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
+ +G+G G V + T VA+K + D P+ + EI +++ H
Sbjct 567 YYNLNKIGQGASGGV----FTAYEQHTNNCVAIKQMNLDLQPK-KDLIINEILVMKDSKH 621
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016
++I+ + + L +VMEY+ GSL D + + + Q+ ++ G+ +LH+
Sbjct 622 KNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMSEPQIAAVCRETLNGLQHLHS 679
Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076
+ IHRD+ + N+LL D +K+ DFG + ++ R +W APE +
Sbjct 680 KGVIHRDIKSDNILLSLDGNIKLTDFGFCAQI---NDSQNKRNTMVGTPYWMAPEVVTRK 736
Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136
++ D+WS G+ E++ + + L IA ++ L +
Sbjct 737 EYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLIATNGTPKIKDEHNLSPVFK--- 792
Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ H + R + +L+
Sbjct 793 ------DFLHFALR---VDPEKRASAHDLLK 814
Score = 175 bits (443), Expect = 1e-43, Method: Composition-based stats.
Identities = 52/293 (18%), Positives = 92/293 (31%), Gaps = 44/293 (15%)
Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651
L+ +GQG V+ ++ V +K ++
Sbjct 570 LNKIGQGASGGVF------------------------TAYEQHTNNCVAIKQMNLDLQPK 605
Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711
+M H ++ + G + +V EY+E G L + +
Sbjct 606 KDLIINEILVMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVV--TFNIMSEPQI 663
Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--- 768
V ++ + L +L +K ++H ++ NILL+ IKL+D G
Sbjct 664 AAVCRETLNGLQHLHSKGVIHRDIKSDNILLS-------LDGNIKLTDFGFCAQINDSQN 716
Query 769 -REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827
R V W+APE + +D W G +E+ +GE P + SP +
Sbjct 717 KRNTMVGTPYWMAPEVVT--RKEYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLI 773
Query 828 QRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876
P L +P +R S +L+ L
Sbjct 774 ATNGTPKIKDEHNLSPVFKDFLHFALRVDPEKRASAHDLLKHPFMNLCAPLNH 826
>sp|Q15349|KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 OS=Homo
sapiens OX=9606 GN=RPS6KA2 PE=1 SV=2
Length=733
Score = 215 bits (547), Expect = 4e-57, Method: Composition-based stats.
Identities = 67/259 (26%), Positives = 109/259 (42%), Gaps = 24/259 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961
LG+G +GKV L G++ A+K LK + R K E DIL + H I+K
Sbjct 65 LGQGSYGKVFLVR-KVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVK 123
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020
Q E L L+++++ G L L + + + ++ + +LH+ I
Sbjct 124 LHYAF--QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGII 181
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
+RDL N+LLD + +KI DFGL+K E ++ + + + APE +
Sbjct 182 YRDLKPENILLDEEGHIKITDFGLSK---EAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQ 238
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
++D WSFGV ++E+LT Q K T L +L P
Sbjct 239 SADWWSFGVLMFEMLTGSLPFQGKDRKE----------------TMALILKAKLGMPQFL 282
Query 1141 PCEVYHLMKNCWETEASFR 1159
E L++ ++ R
Sbjct 283 SGEAQSLLRALFKRNPCNR 301
Score = 191 bits (486), Expect = 2e-49, Method: Composition-based stats.
Identities = 66/307 (21%), Positives = 106/307 (35%), Gaps = 37/307 (12%)
Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930
+L V + + D+G G + + T+ AVK
Sbjct 389 QQDLHKVPVHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATD----TEYAVK 444
Query 931 ALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989
+ + +EI+IL H +II K +D K + LVME + G L D
Sbjct 445 IIDKS-----KRDPSEEIEILLRYGQHPNIITLKDVYDDG--KFVYLVMELMRGGELLDR 497
Query 990 LPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL-DNDRL---VKIGDFGL 1044
+ R + I + M YLH+Q +HRDL N+L D +++ DFG
Sbjct 498 ILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGF 557
Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS--- 1101
AK + G+ + APE LK + A D+WS G+ LY +L
Sbjct 558 AKQLRAGNGLLMT---PCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANG 614
Query 1102 -QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160
P + L IG + ++ D ++ + R
Sbjct 615 PDDTPEEILARIGSGKYALSGGNW-------------DSISDAAKDVVSKMLHVDPHQRL 661
Query 1161 TFENLIP 1167
T ++
Sbjct 662 TAMQVLK 668
Score = 174 bits (442), Expect = 9e-44, Method: Composition-based stats.
Identities = 59/283 (21%), Positives = 108/283 (38%), Gaps = 39/283 (14%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
F + D + L LGQG+ V+ R V G D GQ
Sbjct 51 FEKADPSQFELLKVLGQGSYGKVFLVR-------------------KVKGSDAGQ--LYA 89
Query 641 LKVLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698
+KVL + + ++++V+H + +H + ++ +++ G L
Sbjct 90 MKVLKKATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTR 149
Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758
L +E K +A +LA AL +L + +++ ++ NILL G IK++
Sbjct 150 LSKEVMFTEEDVKFYLA-ELALALDHLHSLGIIYRDLKPENILLDEEG-------HIKIT 201
Query 759 DPGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814
D G+ A+ ++R I ++APE + + + D W FG + E+ G P
Sbjct 202 DFGLSKEAIDHDKRAYSFCGTIEYMAPEVV--NRRGHTQSADWWSFGVLMFEML-TGSLP 258
Query 815 LQSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQR 856
Q + E + +P+ + +L P R
Sbjct 259 FQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPCNR 301
Score = 148 bits (374), Expect = 2e-35, Method: Composition-based stats.
Identities = 47/267 (18%), Positives = 88/267 (33%), Gaps = 24/267 (9%)
Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690
+ + +K++D S D + E ++ + H ++ + V G +V E +
Sbjct 434 HKATDTEYAVKIIDKSKRDPS----EEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELM 489
Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750
G L + R+R + V + + YL ++ +VH ++ NIL G
Sbjct 490 RGGELLDRILRQR-YFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNIL---YRDESG 545
Query 751 TSPFIKLSDPGVGLGALSREERVERIPWL----APECLPGGANSLSTAMDKWGFGATLLE 806
+ I++ D G + + + APE L A D W G L
Sbjct 546 SPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLK--RQGYDAACDIWSLGILLYT 603
Query 807 ICFDGEAPL---QSRSPSEKEHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPS 858
+ G P +P E + + S+ L +P QR +
Sbjct 604 MLA-GFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLT 662
Query 859 FRTILRDLTRLQPHNLADVLTVNPDSP 885
+L+ + L+ D
Sbjct 663 AMQVLKHPWVVNREYLSPNQLSRQDVH 689
>sp|Q00534|CDK6_HUMAN Cyclin-dependent kinase 6 OS=Homo sapiens
OX=9606 GN=CDK6 PE=1 SV=1
Length=326
Score = 204 bits (518), Expect = 4e-57, Method: Composition-based stats.
Identities = 64/318 (20%), Positives = 122/318 (38%), Gaps = 36/318 (11%)
Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTN-DGTGEMVAVKALKADCGPQHRS-GWKQEI 948
+ + + ++GEG +GKV + + G VA+K ++ G + +E+
Sbjct 7 CRADQQYECVAEIGEGAYGKV----FKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREV 62
Query 949 DILRTLY---HEHIIKYKGCCE---DQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQ 999
+LR L H ++++ C E L LV E+V L YL P +
Sbjct 63 AVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQ-DLTTYLDKVPEPGVPTET 121
Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059
+ Q+ G+ +LH+ +HRDL +N+L+ + +K+ DFGLA+ +
Sbjct 122 IKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIY----SFQMALT 177
Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGI 1114
+++ APE L + + D+WS G E+ + K L++IG+
Sbjct 178 SVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGL 237
Query 1115 A--QGQMTVLRLTELLERGERLPRPDKCPCEV----YHLMKNCWETEASFRPTFENLI-- 1166
+ + L + +K ++ L+ C + R + + +
Sbjct 238 PGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSH 297
Query 1167 ---PILKTVHEKYQGQAP 1181
L+ E P
Sbjct 298 PYFQDLERCKENLDSHLP 315
Score = 148 bits (374), Expect = 6e-38, Method: Composition-based stats.
Identities = 45/229 (20%), Positives = 83/229 (36%), Gaps = 47/229 (21%)
Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653
+G+G V++ R G V LK + + +
Sbjct 18 EIGEGAYGKVFKARDLKNGGRF-----------------------VALKRVRVQTGEEGM 54
Query 654 AF--YETASLMSQVS---HTHLAFVHGVCV-----RGPENIMVTEYVEHGPLDVWLRR-E 702
+++ + H ++ + VC R + +V E+V+ L +L +
Sbjct 55 PLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQ-DLTTYLDKVP 113
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
VP + QL L +L + +VH ++ +NIL+ G IKL+D G+
Sbjct 114 EPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQ-------IKLADFGL 166
Query 763 GL---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
++ V + + APE L +S +T +D W G E+
Sbjct 167 ARIYSFQMALTSVVVTLWYRAPEVLLQ--SSYATPVDLWSVGCIFAEMF 213
>sp|P23443|KS6B1_HUMAN Ribosomal protein S6 kinase beta-1 OS=Homo
sapiens OX=9606 GN=RPS6KB1 PE=1 SV=2
Length=525
Score = 210 bits (535), Expect = 4e-57, Method: Composition-based stats.
Identities = 70/292 (24%), Positives = 115/292 (39%), Gaps = 26/292 (9%)
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931
+ ++ S P + +R LG+G +GKV T TG++ A+K
Sbjct 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKV 124
Query 932 LKADC---GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
LK + + K E +IL + H I+ + G+ L L++EY+ G L
Sbjct 125 LKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGK--LYLILEYLSGGELFM 182
Query 989 YLPRHSIG-LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
L R I + +I + +LH + I+RDL N++L++ VK+ DFGL K
Sbjct 183 QLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK- 241
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
E V + + APE L A D WS G +Y++LT
Sbjct 242 --ESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTG---- 295
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+ T+ ++ + +L P E L+K + A+ R
Sbjct 296 -------ENRKKTIDKILKC-----KLNLPPYLTQEARDLLKKLLKRNAASR 335
Score = 154 bits (390), Expect = 3e-38, Method: Composition-based stats.
Identities = 52/280 (19%), Positives = 99/280 (35%), Gaps = 33/280 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
++ + L LG+G V++ R +V G+ + M + R+
Sbjct 84 EKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKVLKKAMIVRNAK------- 135
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
D +H E H + + G + ++ EY+ G L + L R
Sbjct 136 ---DTAHTKAERNILEEV------KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER 186
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
E G +++ AL +L K +++ ++ NI+L G +KL+D G
Sbjct 187 E-GIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-------HVKLTDFG 238
Query 762 VGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ ++ I ++APE L + + A+D W GA + ++ G P
Sbjct 239 LCKESIHDGTVTHTFCGTIEYMAPEILM--RSGHNRAVDWWSLGALMYDML-TGAPPFTG 295
Query 818 RSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQR 856
+ + + LP + L + L R
Sbjct 296 ENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASR 335
>sp|Q9LSC2|Y3589_ARATH PTI1-like tyrosine-protein kinase At3g15890
OS=Arabidopsis thaliana OX=3702 GN=At3g15890 PE=2 SV=1
Length=361
Score = 205 bits (521), Expect = 4e-57, Method: Composition-based stats.
Identities = 69/282 (24%), Positives = 120/282 (43%), Gaps = 18/282 (6%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956
LGEG FG V G +AVK LK + + + E++IL + H
Sbjct 39 FNYDNKLGEGRFGSVYWGQL-----WDGSQIAVKRLK-EWSNREEIDFAVEVEILARIRH 92
Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGM 1011
++++ +G C + E+ LV EY+ SL +L + + + A + +
Sbjct 93 KNLLSVRGYCAEGQER--LLVYEYMQNLSLVSHLHGQHSAECLLDWTKRMKIAISSAQAI 150
Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
AYLH H +H D+ A NVLLD++ ++ DFG K +P+ + S +
Sbjct 151 AYLHDHATPHIVHGDVRASNVLLDSEFEARVTDFGYGKLMPDDDTGDGATK-AKSNNGYI 209
Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVLRLTEL 1127
+PEC K SDV+SFG+ L L++ + PT + + E+
Sbjct 210 SPECDASGKESETSDVYSFGILLMVLVSGKRPLERLNPTTTRCITEWVLPLVYERNFGEI 269
Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169
+++ + +V + C +T+ RPT ++ +L
Sbjct 270 VDKRLSEEHVAEKLKKVVLVGLMCAQTDPDKRPTMSEVVEML 311
Score = 177 bits (448), Expect = 2e-47, Method: Composition-based stats.
Identities = 64/331 (19%), Positives = 119/331 (36%), Gaps = 66/331 (20%)
Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624
+ + P S H + LG+G +VY G+L
Sbjct 16 KKEKEEPSWRVFSLKELH-AATNSFNYDNKLGEGRFGSVYWGQLWDGS------------ 62
Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684
++ +K L + + F +++++ H +L V G C G E +
Sbjct 63 -------------QIAVKRLKEWSNREEIDFAVEVEILARIRHKNLLSVRGYCAEGQERL 109
Query 685 MVTEYVEHGPLDVWLRRERGH---VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGR 738
+V EY+++ L L + + +M +A A A++YL + ++VHG+V
Sbjct 110 LVYEYMQNLSLVSHLHGQHSAECLLDWTKRMKIAISSAQAIAYLHDHATPHIVHGDVRAS 169
Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI------PWLAPECLPGGANSLS 792
N+LL A +++D G G + +++PEC G S
Sbjct 170 NVLLDSEFEA-------RVTDFGYGKLMPDDDTGDGATKAKSNNGYISPECDASGKE--S 220
Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPS--------------EKEHFYQRQHRLPEPS- 837
D + FG LL + G+ PL+ +P+ E+ RL E
Sbjct 221 ETSDVYSFGI-LLMVLVSGKRPLERLNPTTTRCITEWVLPLVYERNFGEIVDKRLSEEHV 279
Query 838 ---CPQLATLTSQCLTYEPTQRPSFRTILRD 865
++ + C +P +RP+ ++
Sbjct 280 AEKLKKVVLVGLMCAQTDPDKRPTMSEVVEM 310
>sp|Q38772|CDC2A_ANTMA Cell division control protein 2 homolog
A OS=Antirrhinum majus OX=4151 GN=CDC2A PE=2 SV=2
Length=294
Score = 202 bits (515), Expect = 4e-57, Method: Composition-based stats.
Identities = 76/294 (26%), Positives = 126/294 (43%), Gaps = 31/294 (11%)
Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952
+K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+
Sbjct 1 MEQYEKVEKIGEGTYGVV----YKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLK 56
Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009
+ H +I++ + EK L LV EY+ L L+ ++ P S + +F QI
Sbjct 57 EMQHGNIVRLQDVV--HSEKRLYLVFEYLDL-DLKKHMDSCPEFSQDPRLVKMFLYQILR 113
Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068
G+AY H+ +HRDL +N+L+D +K+ DFGLA+A R +++
Sbjct 114 GIAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIP---VRTFTHEVVTLWYR 170
Query 1069 APECLKEYK-FYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVL 1122
APE L + + DVWS G E++ DS K ++G + T
Sbjct 171 APEILLGSRHYSTPVDVWSVGCIFAEMVNQRPLFPGDSEIDELFKIFRVMGTPNEE-TWP 229
Query 1123 RLTELLERGERLPR-PDKCPCEV--------YHLMKNCWETEASFRPTFENLIP 1167
+T L + P+ P K V L+ + S R T N +
Sbjct 230 GVTSLPDFKSAFPKWPAKELAAVVPNLDASGLDLLDKMLRLDPSKRITARNALQ 283
Score = 163 bits (412), Expect = 3e-43, Method: Composition-based stats.
Identities = 46/266 (17%), Positives = 92/266 (35%), Gaps = 39/266 (15%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643
++ ++ +G+GT VY+ RDR + LK
Sbjct 1 MEQYEKVEKIGEGTYGVVYKA------------------------RDRVTNETIALKKIR 36
Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702
L+ + SL+ ++ H ++ + V +V EY++ L +
Sbjct 37 LEQEDEGVPSTAIREISLLKEMQHGNIVRLQDVVHSEKRLYLVFEYLDL-DLKKHMDSCP 95
Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ Q+ ++Y + ++H ++ +N+L+ R A +KL+D G+
Sbjct 96 EFSQDPRLVKMFLYQILRGIAYCHSHRVLHRDLKPQNLLIDRRTNA------LKLADFGL 149
Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818
+ V + + APE L G+ ST +D W G E+
Sbjct 150 ARAFGIPVRTFTHEVVTLWYRAPEILL-GSRHYSTPVDVWSVGCIFAEMVNQRPLFPGDS 208
Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844
E ++ E + P + +L
Sbjct 209 EIDELFKIFRVMGTPNEETWPGVTSL 234
>sp|P27361|MK03_HUMAN Mitogen-activated protein kinase 3 OS=Homo
sapiens OX=9606 GN=MAPK3 PE=1 SV=4
Length=379
Score = 206 bits (523), Expect = 4e-57, Method: Composition-based stats.
Identities = 62/301 (21%), Positives = 119/301 (40%), Gaps = 26/301 (9%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
+++ +GEG +G VS + VA+K + + +EI IL
Sbjct 40 PRYTQLQYIGEGAYGMVS----SAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRF 95
Query 955 YHEHIIKYKGCCEDQG---EKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011
HE++I + + + +V + + L L + + F QI G+
Sbjct 96 RHENVIGIRDILRASTLEAMRDVYIVQDLME-TDLYKLLKSQQLSNDHICYFLYQILRGL 154
Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
Y+H+ + +HRDL N+L++ +KI DFGLA+ H++ + + ++ APE
Sbjct 155 KYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPE 214
Query 1072 C-LKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGI--AQGQMTVLRLTE 1126
L + + D+WS G L E+L++ + + ++GI + Q + +
Sbjct 215 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 274
Query 1127 LLERGERLPRP-----------DKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVH 1173
+ R P K + L+ + R T E + P L+ +
Sbjct 275 MKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYY 334
Query 1174 E 1174
+
Sbjct 335 D 335
Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats.
Identities = 38/250 (15%), Positives = 82/250 (33%), Gaps = 48/250 (19%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
TQL ++G+G V D ++ RV +K + P H
Sbjct 43 TQLQYIGEGAYGMV------------------------SSAYDHVRKTRVAIKKISPFEH 78
Query 650 DIA-LAFYETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDVWLRRER 703
++ + H ++ + + + +V + +E L L+ +
Sbjct 79 QTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLME-TDLYKLLKSQ- 136
Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763
+ Q+ L Y+ + N++H ++ N+L+ T+ +K+ D G+
Sbjct 137 -QLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLIN-------TTCDLKICDFGLA 188
Query 764 LGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816
A + + APE + + + ++D W G L E+ +
Sbjct 189 RIADPEHDHTGFLTEYVATRWYRAPE-IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPG 247
Query 817 SRSPSEKEHF 826
+ H
Sbjct 248 KHYLDQLNHI 257
>sp|Q4FZD7|PLK5_MOUSE Inactive serine/threonine-protein kinase
PLK5 OS=Mus musculus OX=10090 GN=Plk5 PE=1 SV=1
Length=595
Score = 212 bits (539), Expect = 4e-57, Method: Composition-based stats.
Identities = 63/268 (24%), Positives = 111/268 (41%), Gaps = 28/268 (10%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960
+G+G F + CY T+ T + A+K + + R ++EI + L H +I+
Sbjct 33 IGKGAFSR----CYKLTDMSTSAVFALKVVPRGGAGRLRLRGKVEREIALHSRLRHRNIV 88
Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019
+ D+ + +V+EY SL L R ++ ++ + + + G+ YLH Q
Sbjct 89 AFHAHFADRDH--VYMVLEYCSRQSLAHVLKVRRTLTEPEVRYYLRGLVSGLRYLHQQRI 146
Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079
+HRDL N L+ + VKIGD GLA V +RV + APE +
Sbjct 147 VHRDLKPSNFFLNKNMEVKIGDLGLAARVGPAGRCHRV---LCGTPNFQAPEVVSRNGHS 203
Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139
SD+W+ G +Y +LT + P + + + + G L P
Sbjct 204 CKSDIWALGCIMYTVLTGTPPFAAAP---------------LSEMYQNIRDGHYLE-PTH 247
Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167
L+ + + RP+ ++L+
Sbjct 248 LSPSARSLIARLLAPDPAERPSLDHLLQ 275
Score = 160 bits (406), Expect = 6e-40, Method: Composition-based stats.
Identities = 62/309 (20%), Positives = 103/309 (33%), Gaps = 37/309 (12%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
+ +G+G + Y+ L + K+ R RG+
Sbjct 28 RRGKLIGKGAFSRCYK--LTDMSTSAVFALKVVPRGGAGRLRLRGKVE------------ 73
Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709
+L S++ H ++ H MV EY L L+ R +
Sbjct 74 -------REIALHSRLRHRNIVAFHAHFADRDHVYMVLEYCSRQSLAHVLKVRR-TLTEP 125
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGAL 767
+ L S L YL + +VH ++ N L + + +K+ D G+ +G
Sbjct 126 EVRYYLRGLVSGLRYLHQQRIVHRDLKPSNFFLNK-------NMEVKIGDLGLAARVGPA 178
Query 768 SREERV--ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825
R RV + APE + N S D W G + + G P + SE
Sbjct 179 GRCHRVLCGTPNFQAPEVVS--RNGHSCKSDIWALGCIMYTVL-TGTPPFAAAPLSEMYQ 235
Query 826 FYQRQHRL-PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884
+ H L P P +L ++ L +P +RPS +L+D Q + + S
Sbjct 236 NIRDGHYLEPTHLSPSARSLIARLLAPDPAERPSLDHLLQDDFFSQGFTPERLPPHSCHS 295
Query 885 PASDPTVFH 893
P
Sbjct 296 PPVFAFPPP 304
>sp|P67999|KS6B1_RAT Ribosomal protein S6 kinase beta-1 OS=Rattus
norvegicus OX=10116 GN=Rps6kb1 PE=1 SV=1
Length=525
Score = 210 bits (534), Expect = 4e-57, Method: Composition-based stats.
Identities = 70/292 (24%), Positives = 115/292 (39%), Gaps = 26/292 (9%)
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931
+ ++ S P + +R LG+G +GKV T TG++ A+K
Sbjct 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKV 124
Query 932 LKADC---GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
LK + + K E +IL + H I+ + G+ L L++EY+ G L
Sbjct 125 LKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGK--LYLILEYLSGGELFM 182
Query 989 YLPRHSIG-LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
L R I + +I + +LH + I+RDL N++L++ VK+ DFGL K
Sbjct 183 QLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK- 241
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
E V + + APE L A D WS G +Y++LT
Sbjct 242 --ESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTG---- 295
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+ T+ ++ + +L P E L+K + A+ R
Sbjct 296 -------ENRKKTIDKILKC-----KLNLPPYLTQEARDLLKKLLKRNAASR 335
Score = 154 bits (390), Expect = 3e-38, Method: Composition-based stats.
Identities = 52/280 (19%), Positives = 99/280 (35%), Gaps = 33/280 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
++ + L LG+G V++ R +V G+ + M + R+
Sbjct 84 EKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKVLKKAMIVRNAK------- 135
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
D +H E H + + G + ++ EY+ G L + L R
Sbjct 136 ---DTAHTKAERNILEEV------KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER 186
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
E G +++ AL +L K +++ ++ NI+L G +KL+D G
Sbjct 187 E-GIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-------HVKLTDFG 238
Query 762 VGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ ++ I ++APE L + + A+D W GA + ++ G P
Sbjct 239 LCKESIHDGTVTHTFCGTIEYMAPEILM--RSGHNRAVDWWSLGALMYDML-TGAPPFTG 295
Query 818 RSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQR 856
+ + + LP + L + L R
Sbjct 296 ENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASR 335
>sp|O93982|HOG1_ZYGRC Mitogen-activated protein kinase HOG1 OS=Zygosaccharomyces
rouxii (strain ATCC 2623 / CBS 732 / NBRC
1130 / NCYC 568 / NRRL Y-229) OX=559307 GN=HOG1 PE=3 SV=2
Length=431
Score = 207 bits (527), Expect = 4e-57, Method: Composition-based stats.
Identities = 65/319 (20%), Positives = 111/319 (35%), Gaps = 31/319 (10%)
Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-K 933
+ + +G G FG V T+ G+ VA+K + K
Sbjct 1 MATHEEFIRTQVFGTVFEITNRYTDLNPVGMGAFGLVC----SATDTLAGQPVAIKKIMK 56
Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993
+E+ +L+ L HE++I + E + V E L L
Sbjct 57 PFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLED-IYFVTEL-QGTDLHRLLQTR 114
Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053
+ + F QI G+ Y+H+ IHRDL N+L++ + +KI DFGLA+
Sbjct 115 PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMT 174
Query 1054 YYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTK 1107
Y S ++ APE + K+ D+WS G E++ +
Sbjct 175 GY------VSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFSEMIEGKPLFPGKDHVHQFSI 228
Query 1108 FLELIGIAQGQMTVLRLTELLER-----GERLPRP-----DKCPCEVYHLMKNCWETEAS 1157
+L+G + +E + R P P + L++ +
Sbjct 229 ITDLLGSPPRDVINTICSENTLKFVTSLPHRDPVPFQERFKTVEPDAVDLLERMLVFDPK 288
Query 1158 FRPTFEN--LIPILKTVHE 1174
R T + + P L H+
Sbjct 289 KRITAADALVHPYLAPYHD 307
Score = 135 bits (340), Expect = 1e-32, Method: Composition-based stats.
Identities = 36/213 (17%), Positives = 69/213 (32%), Gaps = 18/213 (8%)
Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657
V+E R G + D V +K ++ P +A Y
Sbjct 13 FGTVFEITNRYTDLNPVGMGAF---GLVCSATDTLAGQPVAIKKIMKPFSTAVLAKRTYR 69
Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716
L+ + H +L + + + + VTE + L L+ + +
Sbjct 70 ELKLLKHLRHENLICLQDIFLSPLEDIYFVTEL-QGTDLHRLLQTR--PLEKQFVQYFLY 126
Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775
Q+ L Y+ + ++H ++ NIL+ + +K+ D G+ V
Sbjct 127 QILRGLKYVHSAGVIHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 179
Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808
+ APE + +D W G E+
Sbjct 180 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFSEMI 211
>sp|Q8GXQ3|WAKLF_ARATH Wall-associated receptor kinase-like 6
OS=Arabidopsis thaliana OX=3702 GN=WAKL6 PE=2 SV=2
Length=642
Score = 213 bits (542), Expect = 4e-57, Method: Composition-based stats.
Identities = 57/269 (21%), Positives = 94/269 (35%), Gaps = 50/269 (19%)
Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617
LI G R + +L + LGQG + VY+G L
Sbjct 404 KQQLITKNGNVDMSRIFSSKELKK---ATDNFSMNRVLGQGGQGTVYKGMLAEGRI---- 456
Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677
V +K F L+SQ++H ++ + G C
Sbjct 457 ---------------------VAVKRSKVVGEGKMEEFINEVVLLSQINHRNIVKLLGCC 495
Query 678 VRGPENIMVTEYVEHGPLDVWLR--RERGHVPMAW--KMVVAQQLASALSYLENK---NL 730
+ ++V EY+ +G L L E M W ++ +A ++A ALSY+ + +
Sbjct 496 LETEVPVLVYEYIPNGDLFKRLHEKSESNDYTMTWEVRLRIAIEIAGALSYMHSAASIPI 555
Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLP 785
H ++ NILL A K+SD G + ++ PE
Sbjct 556 YHRDIKTTNILLDEKYRA-------KVSDFGTSRSITIAQTHLTTLVAGTFGYMDPEYFL 608
Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAP 814
++ + D + FG L+E+ GE P
Sbjct 609 --SSQYTDKSDVYSFGVVLVELI-TGEKP 634
Score = 212 bits (540), Expect = 9e-57, Method: Composition-based stats.
Identities = 59/215 (27%), Positives = 90/215 (42%), Gaps = 19/215 (9%)
Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954
R LG+G G V G +VAVK K G + E+ +L +
Sbjct 430 DNFSMNRVLGQGGQGTVYKGML-----AEGRIVAVKRSKV-VGEGKMEEFINEVVLLSQI 483
Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQIC 1008
H +I+K GCC + + LV EY+P G L L S + L A +I
Sbjct 484 NHRNIVKLLGCCLET--EVPVLVYEYIPNGDLFKRLHEKSESNDYTMTWEVRLRIAIEIA 541
Query 1009 EGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065
++Y+H+ HRD+ N+LLD K+ DFG ++++ + +
Sbjct 542 GALSYMHSAASIPIYHRDIKTTNILLDEKYRAKVSDFGTSRSITIAQTH--LTTLVAGTF 599
Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100
+ PE ++ SDV+SFGV L EL+T
Sbjct 600 GYMDPEYFLSSQYTDKSDVYSFGVVLVELITGEKP 634
>sp|Q6TJY3|KS6B1_BOVIN Ribosomal protein S6 kinase beta-1 OS=Bos
taurus OX=9913 GN=RPS6KB1 PE=2 SV=1
Length=527
Score = 210 bits (534), Expect = 5e-57, Method: Composition-based stats.
Identities = 70/292 (24%), Positives = 115/292 (39%), Gaps = 26/292 (9%)
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931
+ ++ S P + +R LG+G +GKV T TG++ A+K
Sbjct 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKV 124
Query 932 LKADC---GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
LK + + K E +IL + H I+ + G+ L L++EY+ G L
Sbjct 125 LKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGK--LYLILEYLSGGELFM 182
Query 989 YLPRHSIG-LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
L R I + +I + +LH + I+RDL N++L++ VK+ DFGL K
Sbjct 183 QLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK- 241
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
E V + + APE L A D WS G +Y++LT
Sbjct 242 --ESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTG---- 295
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+ T+ ++ + +L P E L+K + A+ R
Sbjct 296 -------ENRKKTIDKILKC-----KLNLPPYLTQEARDLLKKLLKRNAASR 335
Score = 154 bits (390), Expect = 3e-38, Method: Composition-based stats.
Identities = 52/280 (19%), Positives = 99/280 (35%), Gaps = 33/280 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
++ + L LG+G V++ R +V G+ + M + R+
Sbjct 84 EKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKVLKKAMIVRNAK------- 135
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
D +H E H + + G + ++ EY+ G L + L R
Sbjct 136 ---DTAHTKAERNILEEV------KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER 186
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
E G +++ AL +L K +++ ++ NI+L G +KL+D G
Sbjct 187 E-GIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-------HVKLTDFG 238
Query 762 VGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ ++ I ++APE L + + A+D W GA + ++ G P
Sbjct 239 LCKESIHDGTVTHTFCGTIEYMAPEILM--RSGHNRAVDWWSLGALMYDML-TGAPPFTG 295
Query 818 RSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQR 856
+ + + LP + L + L R
Sbjct 296 ENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASR 335
>sp|Q55CZ1|GDT2_DICDI Probable serine/threonine-protein kinase
gdt2 OS=Dictyostelium discoideum OX=44689 GN=gdt2 PE=2 SV=1
Length=1637
Score = 221 bits (562), Expect = 5e-57, Method: Composition-based stats.
Identities = 85/348 (24%), Positives = 145/348 (42%), Gaps = 40/348 (11%)
Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898
P + T S +T T + + + I+R T + + + + +S ++ F++ +K
Sbjct 1234 PNVETSISLSVTLFSTTKYNEKVIVRFETLDVKQSWSTFVFLRLESELTNIIDFNEIIIK 1293
Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958
+ EG FG V + + VAVK LK + ++EI +L L H +
Sbjct 1294 NY--ISEGTFGIVYRGIWRSS------PVAVKLLKNEYVDHD--EIEKEISLLERLRHPN 1343
Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHA 1016
I+ Y G G +V +Y G L Y+ ++ I + Q + I + AYLH
Sbjct 1344 ILLYVGRFIFSGIHG--IVTDYCSKGCLSKYIHENKYKITIIQKIRILIDISKACAYLHR 1401
Query 1017 QHYIHRDLAARNVLLDNDR-----LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071
HRDL N+L+ + K+ DFG +K E + R V + + E
Sbjct 1402 NGITHRDLKPENILITSLNPKSLVCAKVSDFGTSKETNERYNLQTRR----GTVAYMSNE 1457
Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131
L + + ++D++SFG+ YEL + S P R+ EL+ +
Sbjct 1458 ILSQGSYTKSTDIYSFGMLCYELFSERIPYYSEPH---------------WRIRELVLKN 1502
Query 1132 ERLPRPDKC--PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177
ER + ++ ++ CW S RPTF+ L LK + +KY
Sbjct 1503 ERPSLDQEIFKDTDISDIVTRCWSKNPSQRPTFDYLSKYLKHLLKKYD 1550
Score = 201 bits (511), Expect = 6e-51, Method: Composition-based stats.
Identities = 56/307 (18%), Positives = 114/307 (37%), Gaps = 39/307 (13%)
Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640
+ +D EI +++ +GT VY G R V
Sbjct 1282 TNIIDFNEIIIKNYISEGTFGIVYRGIWRSS--------------------------PVA 1315
Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700
+K+L + D + SL+ ++ H ++ G + + +VT+Y G L ++
Sbjct 1316 VKLLKNEYVD-HDEIEKEISLLERLRHPNILLYVGRFIFSGIHGIVTDYCSKGCLSKYIH 1374
Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760
+ + + K+ + ++ A +YL + H ++ NIL+ L + K+SD
Sbjct 1375 ENKYKITIIQKIRILIDISKACAYLHRNGITHRDLKPENILITSLN--PKSLVCAKVSDF 1432
Query 761 GVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
G R + R + +++ E L G S + + D + FG E+ + P S
Sbjct 1433 GTSKETNERYNLQTRRGTVAYMSNEILSQG--SYTKSTDIYSFGMLCYELFSE-RIPYYS 1489
Query 818 RSPSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873
+ R ++ + ++C + P+QRP+F + + L L
Sbjct 1490 EPHWRIRELVLKNERPSLDQEIFKDTDISDIVTRCWSKNPSQRPTFDYLSKYLKHLLKKY 1549
Query 874 LADVLTV 880
+ +
Sbjct 1550 DINNIIY 1556
>sp|Q90XC2|NEK8_DANRE Serine/threonine-protein kinase Nek8 OS=Danio
rerio OX=7955 GN=nek8 PE=2 SV=1
Length=697
Score = 214 bits (545), Expect = 5e-57, Method: Composition-based stats.
Identities = 69/269 (26%), Positives = 117/269 (43%), Gaps = 30/269 (11%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961
+G G FG V L +V +K + + R + E +L+ L H +II+
Sbjct 10 VGRGAFGIVHLC----RRRTDSALVILKEIPVEQMTRDERLAAQNECQVLKLLSHPNIIE 65
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018
Y + +K+L + MEY P G+L DY+ + + +L QI + ++H +
Sbjct 66 YYENFLE--DKALMIAMEYAPGGTLADYIQKRCNSLLDEDTILHSFVQILLALYHVHNKL 123
Query 1019 YIHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077
+HRDL +N+LLD +VKIGDFG++K + + Y V + +PE +
Sbjct 124 ILHRDLKTQNILLDKHQMIVKIGDFGISKILVSKSKAYTV----VGTPCYISPELCEGKP 179
Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137
+ SD+W+ G LYEL + + ++ L L + G P
Sbjct 180 YNQKSDIWALGCVLYELASLKRAFEAANLPALVL---------------KIMSGTFAPIS 224
Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166
D+ E+ L+ N + S RP ++
Sbjct 225 DRYSPELRQLILNMLNLDPSKRPQLNEIM 253
Score = 169 bits (428), Expect = 3e-42, Method: Composition-based stats.
Identities = 51/293 (17%), Positives = 106/293 (36%), Gaps = 39/293 (13%)
Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645
++ + +G+G V+ R R + + V+LK +
Sbjct 1 MEKYEKTKVVGRGAFGIVHLCRRRTDSA------------------------LVILKEIP 36
Query 646 PSHH--DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703
D LA ++ +SH ++ + + ++ EY G L ++++
Sbjct 37 VEQMTRDERLAAQNECQVLKLLSHPNIIEYYENFLEDKALMIAMEYAPGGTLADYIQKRC 96
Query 704 GH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762
+ + Q+ AL ++ NK ++H ++ +NILL + +K+ D G+
Sbjct 97 NSLLDEDTILHSFVQILLALYHVHNKLILHRDLKTQNILLDKH------QMIVKIGDFGI 150
Query 763 GLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819
+S+ V +++PE G + D W G L E+ A +
Sbjct 151 SKILVSKSKAYTVVGTPCYISPELCEG--KPYNQKSDIWALGCVLYELASLKRAFEAANL 208
Query 820 PSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871
P+ + + P+L L L +P++RP I+ ++P
Sbjct 209 PALVLKIMSGTFAPISDRYSPELRQLILNMLNLDPSKRPQLNEIMAHAICIRP 261
>sp|P51952|CDK7_RAT Cyclin-dependent kinase 7 (Fragment) OS=Rattus
norvegicus OX=10116 GN=Cdk7 PE=1 SV=2
Length=329
Score = 204 bits (518), Expect = 5e-57, Method: Composition-based stats.
Identities = 69/305 (23%), Positives = 121/305 (40%), Gaps = 35/305 (11%)
Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYHE 957
LGEG F V Y + T ++VA+K +K + + G +EI +L+ L H
Sbjct 9 FLGEGQFATV----YKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHP 64
Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI--GLAQLLLFAQQICEGMAYLH 1015
+II + ++ LV +++ L + +S+ + + + +G+ YLH
Sbjct 65 NIIGLLDAFGHKS--NISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 121
Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075
+HRDL N+LLD + ++K+ DFGLAK+ + Y + ++ APE L
Sbjct 122 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNWAYTHQ---VVTRWYRAPELLFG 178
Query 1076 -YKFYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIA--QGQMTVLRLTEL 1127
+ D+W+ G L ELL DS T+ E +G + + L +
Sbjct 179 ARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDY 238
Query 1128 LERGERLPRPDK-----CPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182
+ P + ++ L++ + R T + KY P
Sbjct 239 VTFKSFPGIPLQHIFIAAGDDLLELIQGLFLFNPCTRITASQ------ALRTKYFSNRPG 292
Query 1183 VFSVC 1187
C
Sbjct 293 PTPGC 297
Score = 156 bits (394), Expect = 1e-40, Method: Composition-based stats.
Identities = 47/264 (18%), Positives = 86/264 (33%), Gaps = 42/264 (16%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649
+L LG+G VY+ RD+ V +K + H
Sbjct 5 EKLDFLGEGQFATVYKA------------------------RDKNTNQIVAIKKIKLGHR 40
Query 650 DIALA-----FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
A L+ ++SH ++ + +V +++E L+V ++
Sbjct 41 SEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFME-TDLEVIIKDNSL 99
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+ + L YL ++H ++ N+LL G+ +KL+D G+
Sbjct 100 VLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGV-------LKLADFGLAK 152
Query 765 GALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
S +V + APE L GA +D W G L E+
Sbjct 153 SFGSPNWAYTHQVVTRWYRAPELLF-GARMYGVGVDMWAVGCILAELLLRVPFLPGDSDL 211
Query 821 SEKEHFYQRQHRLPEPSCPQLATL 844
+ ++ E P + +L
Sbjct 212 DQLTRIFETLGTPTEEQWPDMCSL 235
>sp|Q8BSK8|KS6B1_MOUSE Ribosomal protein S6 kinase beta-1 OS=Mus
musculus OX=10090 GN=Rps6kb1 PE=1 SV=2
Length=525
Score = 210 bits (534), Expect = 5e-57, Method: Composition-based stats.
Identities = 70/292 (24%), Positives = 115/292 (39%), Gaps = 26/292 (9%)
Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931
+ ++ S P + +R LG+G +GKV T TG++ A+K
Sbjct 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKV 124
Query 932 LKADC---GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988
LK + + K E +IL + H I+ + G+ L L++EY+ G L
Sbjct 125 LKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGK--LYLILEYLSGGELFM 182
Query 989 YLPRHSIG-LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047
L R I + +I + +LH + I+RDL N++L++ VK+ DFGL K
Sbjct 183 QLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK- 241
Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107
E V + + APE L A D WS G +Y++LT
Sbjct 242 --ESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTG---- 295
Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159
+ T+ ++ + +L P E L+K + A+ R
Sbjct 296 -------ENRKKTIDKILKC-----KLNLPPYLTQEARDLLKKLLKRNAASR 335
Score = 154 bits (389), Expect = 3e-38, Method: Composition-based stats.
Identities = 52/280 (19%), Positives = 99/280 (35%), Gaps = 33/280 (12%)
Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641
++ + L LG+G V++ R +V G+ + M + R+
Sbjct 84 EKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKVLKKAMIVRNAK------- 135
Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701
D +H E H + + G + ++ EY+ G L + L R
Sbjct 136 ---DTAHTKAERNILEEV------KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER 186
Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761
E G +++ AL +L K +++ ++ NI+L G +KL+D G
Sbjct 187 E-GIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-------HVKLTDFG 238
Query 762 VGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817
+ ++ I ++APE L + + A+D W GA + ++ G P
Sbjct 239 LCKESIHDGTVTHTFCGTIEYMAPEILM--RSGHNRAVDWWSLGALMYDML-TGAPPFTG 295
Query 818 RSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQR 856
+ + + LP + L + L R
Sbjct 296 ENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASR 335
>sp|P10665|KS6AA_XENLA Ribosomal protein S6 kinase 2 alpha OS=Xenopus
laevis OX=8355 GN=rps6ka PE=1 SV=1
Length=733
Score = 214 bits (546), Expect = 5e-57, Method: Composition-based stats.
Identities = 64/259 (25%), Positives = 113/259 (44%), Gaps = 24/259 (9%)
Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961
LG+G FGKV L T ++ A+K LK + R K E DIL ++H +++
Sbjct 68 LGQGSFGKVFLVR-KITPPDANQLYAMKVLKKATLKVRDRVRTKMERDILADVHHPFVVR 126
Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020
Q E L L+++++ G L L + + + ++ G+ +LH+ I
Sbjct 127 LHYAF--QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGII 184
Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080
+RDL N+LLD + +K+ DFGL+K E ++ + V + APE + +
Sbjct 185 YRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKKAYSFCGTVEYMAPEVVNRQGHSH 241
Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140
++D WS+GV ++E+LT Q K + + +L P
Sbjct 242 SADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILK----------------AKLGMPQFL 285
Query 1141 PCEVYHLMKNCWETEASFR 1159
E L++ ++ + R
Sbjct 286 SNEAQSLLRALFKRNPTNR 304
Score = 188 bits (478), Expect = 3e-48, Method: Composition-based stats.
Identities = 58/290 (20%), Positives = 102/290 (35%), Gaps = 29/290 (10%)
Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943
+ +G G + + GT AVK + + +
Sbjct 403 PKTHSKNILFMDVYTVRETIGVGSYSVCKRC----VHKGTNMEYAVKVI-----DKTKRD 453
Query 944 WKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLL 1001
+EI+ILR H +II K ++ S+ +V E + G L D + R +
Sbjct 454 PSEEIEILRRYGQHPNIIALKDVYKEGN--SIYVVTELMRGGELLDRILRQKFFSEREAS 511
Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVL-LDNDRL---VKIGDFGLAKAVPEGHEYYRV 1057
+C+ + LH+Q +HRDL N+L +D ++I DFG AK + +
Sbjct 512 SVLFTVCKTVENLHSQGVVHRDLKPSNILYVDESGDPESIRICDFGFAKQLRADNGLLMT 571
Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117
+ APE LK + D+WS G+ LY +L + L +
Sbjct 572 ---PCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANG------LGDTPEE 622
Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
+ + + RG + L+ + R T + ++
Sbjct 623 ILARIGSGKFTLRGGNW---NTVSAAAKDLVSRMLHVDPHKRLTAKQVLQ 669
Score = 174 bits (441), Expect = 1e-43, Method: Composition-based stats.
Identities = 63/344 (18%), Positives = 118/344 (34%), Gaps = 40/344 (12%)
Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627
+ P T ++ + S + DQ + L LGQG+ V+ + D + L
Sbjct 42 KEFPITHHVKEGS-EKADQSDFVLLKVLGQGSFGKVFL----------VRKITPPDANQL 90
Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIM 685
+KVL + + +++ V H + +H + +
Sbjct 91 Y-----------AMKVLKKATLKVRDRVRTKMERDILADVHHPFVVRLHYAFQTEGKLYL 139
Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745
+ +++ G L L +E K +A +LA L +L + +++ ++ NILL
Sbjct 140 ILDFLRGGDLFTRLSKEVMFTEEDVKFYLA-ELALGLDHLHSLGIIYRDLKPENILLDEE 198
Query 746 GLAEGTSPFIKLSDPGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFG 801
G IKL+D G+ A+ E++ + ++APE + +S S D W +G
Sbjct 199 G-------HIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS--ADWWSYG 249
Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQRPSFR 860
+ E+ G P Q + E + +P+ + +L PT R
Sbjct 250 VLMFEML-TGSLPFQGKDRKETMTLILKAKLGMPQFLSNEAQSLLRALFKRNPTNRLGSA 308
Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904
+ + QP S P
Sbjct 309 MEGAEEIKRQPFFSTIDWNKLFRREMSPPFKPAVTQADDTYYFD 352
Score = 147 bits (370), Expect = 7e-35, Method: Composition-based stats.
Identities = 49/278 (18%), Positives = 92/278 (33%), Gaps = 28/278 (10%)
Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664
+ L ++ E + +G + +KV+D + D + E ++ +
Sbjct 408 KNILFMDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKTKRDPS----EEIEILRR 463
Query 665 V-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723
H ++ + V G +VTE + G L + R++ V + +
Sbjct 464 YGQHPNIIALKDVYKEGNSIYVVTELMRGGELLDRILRQKF-FSEREASSVLFTVCKTVE 522
Query 724 YLENKNLVHGNVCGRNIL-LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL--- 779
L ++ +VH ++ NIL + G E I++ D G + + +
Sbjct 523 NLHSQGVVHRDLKPSNILYVDESGDPES----IRICDFGFAKQLRADNGLLMTPCYTANF 578
Query 780 -APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ---SRSPSEKE------HFYQR 829
APE L D W G L + G P +P E F R
Sbjct 579 VAPEVLK--RQGYDEGCDIWSLGILLYTMLA-GYTPFANGLGDTPEEILARIGSGKFTLR 635
Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867
L S+ L +P +R + + +L+
Sbjct 636 GGN-WNTVSAAAKDLVSRMLHVDPHKRLTAKQVLQHEW 672
>sp|Q06BH3|SRF1_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 1 OS=Arabidopsis
thaliana OX=3702 GN=SRF1 PE=1 SV=2
Length=775
Score = 215 bits (548), Expect = 5e-57, Method: Composition-based stats.
Identities = 73/372 (20%), Positives = 144/372 (39%), Gaps = 32/372 (9%)
Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881
E + + S P + + ++ EP + RT + L V ++
Sbjct 415 EIDMNGNAMDLMHPSSIPPIKRVIAK--ATEPAEASLKRTTSKSHGPLTAVKHFTVASLQ 472
Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941
+ + +G G G V G++ AV+ L
Sbjct 473 QHTNSFSHENL----------IGTGMLGSVYRAELPG-----GKLFAVRKLDKKSPNHEE 517
Query 942 SG-WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSI 995
G + + ++ + + H +I++ G C + ++ L+ EY G+L D L + +
Sbjct 518 EGKFLELVNNIDRIRHANIVQLVGFCSEHSQR--LLIHEYCRNGTLHDLLHIDDRLKIEL 575
Query 996 GLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052
+ A + + + YLH IHR+ + N+LLD+D V + D GLA + G
Sbjct 576 SWNVRVRIALEAAKALEYLHEICDPPSIHRNFKSANILLDDDIRVHVSDCGLAPLISSG- 634
Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE-L 1111
++ + + APE + + DV+SFGV + ELLT S + + L
Sbjct 635 AVSQLSGQLLAAYGYGAPE-FEYGIYTMKCDVYSFGVVMLELLTGRKSYDKKRDRGEQFL 693
Query 1112 IGIAQGQM-TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170
+ A Q+ + L ++++ + P K ++ C ++E +RP ++ L
Sbjct 694 VRWAIPQLHDIDALAKMVDPSLKGDYPAKSLSHFADVISRCVQSEPEYRPLMSEVVQDLS 753
Query 1171 TVHEKYQGQAPS 1182
+ ++ + S
Sbjct 754 DMIQREHRRNDS 765
Score = 165 bits (418), Expect = 1e-40, Method: Composition-based stats.
Identities = 58/352 (16%), Positives = 116/352 (33%), Gaps = 70/352 (20%)
Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625
G + + ++ L H + + +G G +VY L
Sbjct 458 GPLTAVKHFTVASLQQH---TNSFSHENLIGTGMLGSVYRAELPGGKLF----------- 503
Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPEN 683
++ LD + F E + + ++ H ++ + G C +
Sbjct 504 --------------AVRKLDKKSPNHEEEGKFLELVNNIDRIRHANIVQLVGFCSEHSQR 549
Query 684 IMVTEYVEHGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCG 737
+++ EY +G L L +R + ++W ++ +A + A AL YL +H N
Sbjct 550 LLIHEYCRNGTLHDLLHIDDRLKIELSWNVRVRIALEAAKALEYLHEICDPPSIHRNFKS 609
Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANSL 791
NILL + +SD G+ S + + + APE
Sbjct 610 ANILLD-------DDIRVHVSDCGLAPLISSGAVSQLSGQLLAAYGYGAPE---FEYGIY 659
Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------------- 837
+ D + FG +LE+ ++ + R E+ +L +
Sbjct 660 TMKCDVYSFGVVMLELLTGRKSYDKKRDRGEQFLVRWAIPQLHDIDALAKMVDPSLKGDY 719
Query 838 ----CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885
A + S+C+ EP RP +++DL+ + + +
Sbjct 720 PAKSLSHFADVISRCVQSEPEYRPLMSEVVQDLSDMIQREHRRNDSNGDNQY 771
>sp|Q8IWQ3|BRSK2_HUMAN Serine/threonine-protein kinase BRSK2 OS=Homo
sapiens OX=9606 GN=BRSK2 PE=1 SV=3
Length=736
Score = 215 bits (547), Expect = 5e-57, Method: Composition-based stats.
Identities = 71/282 (25%), Positives = 119/282 (42%), Gaps = 29/282 (10%)
Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQE 947
+ + + LG+G G V L + T + VA+K + + ++E
Sbjct 11 QHAQYVGPYRLEKTLGKGQTGLVKLG----VHCVTCQKVAIKIVNREKLSESVLMKVERE 66
Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006
I IL+ + H H++K E++ K L LV+E+V G L DYL + + + F +Q
Sbjct 67 IAILKLIEHPHVLKLHDVYENK--KYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 124
Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066
I + + H+ HRDL N+LLD ++I DFG+A + E
Sbjct 125 IISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASL----QVGDSLLETSCGSPH 180
Query 1067 WYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125
+ PE ++ K+ +DVWS GV L+ LL + +L
Sbjct 181 YACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDD---------------NLRQLL 225
Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167
E ++RG P P + L++ E +A+ R T E++
Sbjct 226 EKVKRGV-FHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQK 266
Score = 166 bits (420), Expect = 5e-41, Method: Composition-based stats.
Identities = 48/300 (16%), Positives = 98/300 (33%), Gaps = 40/300 (13%)
Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647
LG+G V G V +V +K+++
Sbjct 20 RLEKTLGKGQTGLVKLGVHCVTCQ------------------------KVAIKIVNREKL 55
Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707
+ + +++ + H H+ +H V +V E+V G L +L ++G +
Sbjct 56 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYL-VKKGRLT 114
Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767
+Q+ SAL + + ++ H ++ N+LL I+++D G+ +
Sbjct 115 PKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKN-------NIRIADFGMASLQV 167
Query 768 SR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824
E + PE + G D W G L + G P + +
Sbjct 168 GDSLLETSCGSPHYACPEVIRGEKYD-GRKADVWSCGVILFALLV-GALPFDDDNLRQLL 225
Query 825 HFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883
+R +P P +L + + +R + I + + + N + P
Sbjct 226 EKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWYIGGKNEPEPEQPIPR 285
>sp|Q2QAV0|TIO_ARATH Serine/threonine-protein kinase TIO OS=Arabidopsis
thaliana OX=3702 GN=TIO PE=1 SV=1
Length=1322
Score = 220 bits (560), Expect = 5e-57, Method: Composition-based stats.
Identities = 74/267 (28%), Positives = 114/267 (43%), Gaps = 28/267 (10%)
Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK-ALKADCGPQHRSGWKQEIDILRTLY 955
I +GEG FG+V Y TG+ VA+K +K + +QEI+ILR L
Sbjct 6 YHVIELVGEGSFGRV----YKGRRKYTGQTVAMKFIMKQGKTDKDIHSLRQEIEILRKLK 61
Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYL 1014
HE+II+ E+ E +V E+ G L + L + Q+ A+Q+ + + YL
Sbjct 62 HENIIEMLDSFENARE--FCVVTEFAQ-GELFEILEDDKCLPEEQVQAIAKQLVKALDYL 118
Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074
H+ IHRD+ +N+L+ +VK+ DFG A+A+ V + APE +K
Sbjct 119 HSNRIIHRDMKPQNILIGAGSVVKLCDFGFARAMSTN---TVVLRSIKGTPLYMAPELVK 175
Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134
E + D+WS GV LYEL + +V L + + +
Sbjct 176 EQPYDRTVDLWSLGVILYELYVGQPPFYT---------------NSVYALIRHIVKDP-V 219
Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPT 1161
PD+ +K E R T
Sbjct 220 KYPDEMSTYFESFLKGLLNKEPHSRLT 246
Score = 182 bits (462), Expect = 3e-45, Method: Composition-based stats.
Identities = 49/276 (18%), Positives = 98/276 (36%), Gaps = 41/276 (15%)
Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLD 645
++ + +G+G+ VY+GR + G V +K ++
Sbjct 4 EDYHVIELVGEGSFGRVYKGRRKYTGQ------------------------TVAMKFIMK 39
Query 646 PSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704
D + + + ++ ++ H ++ + E +VTE+ + G L L ++
Sbjct 40 QGKTDKDIHSLRQEIEILRKLKHENIIEMLDSFENAREFCVVTEFAQ-GELFEILEDDKC 98
Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764
+P +A+QL AL YL + ++H ++ +NIL+ G +KL D G
Sbjct 99 -LPEEQVQAIAKQLVKALDYLHSNRIIHRDMKPQNILI-------GAGSVVKLCDFGFAR 150
Query 765 GALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820
+ ++APE + +D W G L E+ +
Sbjct 151 AMSTNTVVLRSIKGTPLYMAPELVKE--QPYDRTVDLWSLGVILYELYVGQPPFYTNSVY 208
Query 821 SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856
+ H + + P+ + L EP R
Sbjct 209 ALIRHIVKDPVKYPDEMSTYFESFLKGLLNKEPHSR 244
>sp|O73792|TIE1_DANRE Tyrosine-protein kinase receptor Tie-1 (Fragment)
OS=Danio rerio OX=7955 GN=tie1 PE=1 SV=1
Length=184
Score = 198 bits (503), Expect = 5e-57, Method: Composition-based stats.
Identities = 69/180 (38%), Positives = 91/180 (51%), Gaps = 18/180 (10%)
Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058
QLL FA + GM YL + +IHRDLAARNVL+ ++ + KI DFGL++ G E Y +
Sbjct 1 QLLQFAADVATGMHYLSDKQFIHRDLAARNVLVGDNLVAKIADFGLSR----GEEVYVKK 56
Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118
G PV W A E L + SDVWSFGV L+E+++ L G
Sbjct 57 TMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCG 102
Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178
MT L E L +G R+ +P C EVY LM+ CW RP F + L + E +
Sbjct 103 MTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRMQEARKA 162
Score = 160 bits (405), Expect = 9e-44, Method: Composition-based stats.
Identities = 46/183 (25%), Positives = 79/183 (43%), Gaps = 14/183 (8%)
Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALS 768
+ A +A+ + YL +K +H ++ RN+L+ G + K++D G+ G +
Sbjct 1 QLLQFAADVATGMHYLSDKQFIHRDLAARNVLV-------GDNLVAKIADFGLSRGEEVY 53
Query 769 REERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826
++ + R+P W+A E L + +T D W FG L EI G P + +E
Sbjct 54 VKKTMGRLPVRWMAIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEK 111
Query 827 YQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884
+ +R+ P ++ L QC P +RP F I L R+Q A V ++
Sbjct 112 LPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRMQEARKAYVNMALFEN 171
Query 885 PAS 887
Sbjct 172 FTY 174
Lambda K H a alpha
0.318 0.134 0.397 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 140973851148
Database: uniprot_sprot.fasta
Posted date: Aug 1, 2024 3:29 PM
Number of letters in database: 207,016,062
Number of sequences in database: 571,864
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40