PSIBLAST 2.11.0+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Stephen F. Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: uniprot_sprot.fasta 571,864 sequences; 207,016,062 total letters Results from round 1 Query= sp|P29597|TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 OS=Homo sapiens OX=9606 GN=TYK2 PE=1 SV=3 Length=1187 Score E Sequences producing significant alignments: (Bits) Value sp|P29597|TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 OS... 2455 0.0 sp|Q9R117|TYK2_MOUSE Non-receptor tyrosine-protein kinase TYK2 OS... 1919 0.0 sp|P23458|JAK1_HUMAN Tyrosine-protein kinase JAK1 OS=Homo sapiens... 1014 0.0 sp|P52332|JAK1_MOUSE Tyrosine-protein kinase JAK1 OS=Mus musculus... 1013 0.0 sp|O12990|JAK1_DANRE Tyrosine-protein kinase JAK1 OS=Danio rerio ... 990 0.0 sp|Q09178|JAK1_CYPCA Tyrosine-protein kinase JAK1 OS=Cyprinus car... 920 0.0 sp|Q75R65|JAK2_CHICK Tyrosine-protein kinase JAK2 OS=Gallus gallu... 781 0.0 sp|Q62689|JAK2_RAT Tyrosine-protein kinase JAK2 OS=Rattus norvegi... 765 0.0 sp|Q62120|JAK2_MOUSE Tyrosine-protein kinase JAK2 OS=Mus musculus... 764 0.0 sp|Q5RB23|JAK2_PONAB Tyrosine-protein kinase JAK2 OS=Pongo abelii... 759 0.0 sp|O60674|JAK2_HUMAN Tyrosine-protein kinase JAK2 OS=Homo sapiens... 759 0.0 sp|O19064|JAK2_PIG Tyrosine-protein kinase JAK2 OS=Sus scrofa OX=... 759 0.0 sp|P52333|JAK3_HUMAN Tyrosine-protein kinase JAK3 OS=Homo sapiens... 684 0.0 sp|Q62137|JAK3_MOUSE Tyrosine-protein kinase JAK3 OS=Mus musculus... 671 0.0 sp|Q63272|JAK3_RAT Tyrosine-protein kinase JAK3 OS=Rattus norvegi... 660 0.0 sp|O54967|ACK1_MOUSE Activated CDC42 kinase 1 OS=Mus musculus OX=... 182 3e-45 sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens OX=... 181 5e-45 sp|Q17R13|ACK1_BOVIN Activated CDC42 kinase 1 OS=Bos taurus OX=99... 179 2e-44 sp|Q5U2X5|ACK1_RAT Activated CDC42 kinase 1 OS=Rattus norvegicus ... 179 2e-44 sp|P24786|NTRK3_PIG NT-3 growth factor receptor OS=Sus scrofa OX=... 177 2e-44 sp|Q91044|NTRK3_CHICK NT-3 growth factor receptor OS=Gallus gallu... 177 4e-44 sp|Q5IS37|NTRK3_PANTR NT-3 growth factor receptor OS=Pan troglody... 174 2e-43 sp|Q5IFJ9|NTRK3_MACFA NT-3 growth factor receptor OS=Macaca fasci... 174 3e-43 sp|Q6VNS1|NTRK3_MOUSE NT-3 growth factor receptor OS=Mus musculus... 174 3e-43 sp|Q3UFB7|NTRK1_MOUSE High affinity nerve growth factor receptor ... 173 5e-43 sp|Q5IS82|NTRK3_SAIBB NT-3 growth factor receptor OS=Saimiri boli... 172 1e-42 sp|P35739|NTRK1_RAT High affinity nerve growth factor receptor OS... 171 2e-42 sp|Q63604|NTRK2_RAT BDNF/NT-3 growth factors receptor OS=Rattus n... 171 2e-42 sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens O... 164 9e-42 sp|Q16620|NTRK2_HUMAN BDNF/NT-3 growth factors receptor OS=Homo s... 169 9e-42 sp|F1N9Y5|KSYK_CHICK Tyrosine-protein kinase SYK OS=Gallus gallus... 166 9e-42 sp|P15209|NTRK2_MOUSE BDNF/NT-3 growth factors receptor OS=Mus mu... 169 9e-42 sp|P25911|LYN_MOUSE Tyrosine-protein kinase Lyn OS=Mus musculus O... 164 1e-41 sp|P53356|HTK16_HYDVU Tyrosine-protein kinase HTK16 OS=Hydra vulg... 168 1e-41 sp|Q91987|NTRK2_CHICK BDNF/NT-3 growth factors receptor OS=Gallus... 168 2e-41 sp|Q07014|LYN_RAT Tyrosine-protein kinase Lyn OS=Rattus norvegicu... 163 3e-41 sp|Q95KR7|LCK_SAISC Proto-oncogene tyrosine-protein kinase LCK OS... 163 3e-41 sp|P42679|MATK_HUMAN Megakaryocyte-associated tyrosine-protein ki... 163 3e-41 sp|Q61527|ERBB4_MOUSE Receptor tyrosine-protein kinase erbB-4 OS=... 169 3e-41 sp|Q5PXS1|LCK_AOTNA Tyrosine-protein kinase Lck OS=Aotus nancymaa... 162 4e-41 sp|Q14289|FAK2_HUMAN Protein-tyrosine kinase 2-beta OS=Homo sapie... 168 4e-41 sp|P41241|CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus musculus O... 161 5e-41 sp|P32577|CSK_RAT Tyrosine-protein kinase CSK OS=Rattus norvegicu... 161 5e-41 sp|P04629|NTRK1_HUMAN High affinity nerve growth factor receptor ... 167 5e-41 sp|P41242|MATK_MOUSE Megakaryocyte-associated tyrosine-protein ki... 162 6e-41 sp|Q16288|NTRK3_HUMAN NT-3 growth factor receptor OS=Homo sapiens... 166 7e-41 sp|P41240|CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo sapiens O... 160 7e-41 sp|P70600|FAK2_RAT Protein-tyrosine kinase 2-beta OS=Rattus norve... 167 8e-41 sp|Q0VBZ0|CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos taurus OX=... 160 1e-40 sp|Q15303|ERBB4_HUMAN Receptor tyrosine-protein kinase erbB-4 OS=... 167 1e-40 sp|P06240|LCK_MOUSE Proto-oncogene tyrosine-protein kinase LCK OS... 160 2e-40 sp|P42689|SRK3_SPOLA Tyrosine-protein kinase SRK3 (Fragment) OS=S... 156 2e-40 sp|P11273|ERBB_AVIEU Tyrosine-protein kinase transforming protein... 161 2e-40 sp|P41243|MATK_RAT Megakaryocyte-associated tyrosine-protein kina... 160 2e-40 sp|Q9QVP9|FAK2_MOUSE Protein-tyrosine kinase 2-beta OS=Mus muscul... 166 2e-40 sp|P42683|LCK_CHICK Proto-oncogene tyrosine-protein kinase LCK OS... 160 2e-40 sp|Q62956|ERBB4_RAT Receptor tyrosine-protein kinase erbB-4 OS=Ra... 166 2e-40 sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens OX=9... 166 3e-40 sp|P41239|CSK_CHICK Tyrosine-protein kinase CSK OS=Gallus gallus ... 158 4e-40 sp|Q01621|LCK_RAT Proto-oncogene tyrosine-protein kinase LCK OS=R... 159 4e-40 sp|P34152|FAK1_MOUSE Focal adhesion kinase 1 OS=Mus musculus OX=1... 165 5e-40 sp|P06239|LCK_HUMAN Tyrosine-protein kinase Lck OS=Homo sapiens O... 159 5e-40 sp|O35346|FAK1_RAT Focal adhesion kinase 1 OS=Rattus norvegicus O... 165 6e-40 sp|P42685|FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo sapiens O... 159 7e-40 sp|Q922K9|FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus musculus O... 159 7e-40 sp|P42690|SRK4_SPOLA Tyrosine-protein kinase isoform SRK4 OS=Spon... 159 7e-40 sp|P08631|HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo sapiens O... 159 1e-39 sp|Q24592|JAK_DROME Tyrosine-protein kinase hopscotch OS=Drosophi... 164 1e-39 sp|Q03142|FGFR4_MOUSE Fibroblast growth factor receptor 4 OS=Mus ... 162 1e-39 sp|P22455|FGFR4_HUMAN Fibroblast growth factor receptor 4 OS=Homo... 162 1e-39 sp|Q07407|FGFR1_DROME Fibroblast growth factor receptor homolog 1... 161 1e-39 sp|Q62662|FRK_RAT Tyrosine-protein kinase FRK OS=Rattus norvegicu... 157 2e-39 sp|Q24145|SHARK_DROME Tyrosine-protein kinase Shark OS=Drosophila... 162 2e-39 sp|Q498D6|FGFR4_RAT Fibroblast growth factor receptor 4 OS=Rattus... 161 3e-39 sp|P00522|ABL_DROME Tyrosine-protein kinase Abl OS=Drosophila mel... 163 3e-39 sp|Q91287|FGFR3_PLEWA Fibroblast growth factor receptor 3 OS=Pleu... 161 3e-39 sp|Q04589|FGFR1_RAT Fibroblast growth factor receptor 1 OS=Rattus... 161 4e-39 sp|P48025|KSYK_MOUSE Tyrosine-protein kinase SYK OS=Mus musculus ... 159 4e-39 sp|P21804|FGFR1_CHICK Fibroblast growth factor receptor 1 OS=Gall... 160 5e-39 sp|P43405|KSYK_HUMAN Tyrosine-protein kinase SYK OS=Homo sapiens ... 158 5e-39 sp|P00534|ERBB_ALV Tyrosine-protein kinase transforming protein e... 158 6e-39 sp|Q95YD4|KIN32_CAEEL Inactive tyrosine-protein kinase kin-32 OS=... 160 6e-39 sp|P00535|ERBB_AVIER Tyrosine-protein kinase transforming protein... 158 6e-39 sp|P50545|HCK_RAT Tyrosine-protein kinase HCK OS=Rattus norvegicu... 156 7e-39 sp|P08103|HCK_MOUSE Tyrosine-protein kinase HCK OS=Mus musculus O... 156 8e-39 sp|P11362|FGFR1_HUMAN Fibroblast growth factor receptor 1 OS=Homo... 160 9e-39 sp|P22182|FGFR1_XENLA Fibroblast growth factor receptor 1 OS=Xeno... 160 9e-39 sp|Q91009|NTRK1_CHICK High affinity nerve growth factor receptor ... 159 9e-39 sp|Q00944|FAK1_CHICK Focal adhesion kinase 1 OS=Gallus gallus OX=... 160 1e-38 sp|P16092|FGFR1_MOUSE Fibroblast growth factor receptor 1 OS=Mus ... 159 1e-38 sp|Q90Z00|FGR1A_DANRE Fibroblast growth factor receptor 1-A OS=Da... 159 1e-38 sp|Q95M30|HCK_MACFA Tyrosine-protein kinase HCK OS=Macaca fascicu... 154 2e-38 sp|P18460|FGFR3_CHICK Fibroblast growth factor receptor 3 OS=Gall... 158 2e-38 sp|Q91738|FAK1_XENLA Focal adhesion kinase 1 OS=Xenopus laevis OX... 159 2e-38 sp|P42688|SRK2_SPOLA Tyrosine-protein kinase SRK2 (Fragment) OS=S... 150 2e-38 sp|Q09147|FGFR2_DROME Fibroblast growth factor receptor homolog 2... 159 3e-38 sp|O42127|FGFR3_XENLA Fibroblast growth factor receptor 3 OS=Xeno... 158 3e-38 sp|P13388|XMRK_XIPMA Melanoma receptor tyrosine-protein kinase OS... 159 3e-38 sp|P22607|FGFR3_HUMAN Fibroblast growth factor receptor 3 OS=Homo... 158 3e-38 sp|P18461|FGFR2_CHICK Fibroblast growth factor receptor 2 OS=Gall... 158 4e-38 sp|Q9V9J3|SRC42_DROME Tyrosine-protein kinase Src42A OS=Drosophil... 154 4e-38 sp|Q90413|FGFR4_DANRE Fibroblast growth factor receptor 4 OS=Dani... 158 4e-38 sp|Q91147|FGFR2_NOTVI Fibroblast growth factor receptor 2 OS=Noto... 157 4e-38 sp|P43403|ZAP70_HUMAN Tyrosine-protein kinase ZAP-70 OS=Homo sapi... 155 4e-38 sp|Q91286|FGFR2_PLEWA Fibroblast growth factor receptor 2 OS=Pleu... 157 5e-38 sp|P21802|FGFR2_HUMAN Fibroblast growth factor receptor 2 OS=Homo... 157 5e-38 sp|P07949|RET_HUMAN Proto-oncogene tyrosine-protein kinase recept... 158 6e-38 sp|P21803|FGFR2_MOUSE Fibroblast growth factor receptor 2 OS=Mus ... 157 6e-38 sp|Q00655|KSYK_PIG Tyrosine-protein kinase SYK OS=Sus scrofa OX=9... 155 7e-38 sp|Q03351|NTRK3_RAT NT-3 growth factor receptor OS=Rattus norvegi... 157 7e-38 sp|Q91288|FGFR4_PLEWA Fibroblast growth factor receptor 4 OS=Pleu... 157 8e-38 sp|Q5RB22|ERBB3_PONAB Receptor tyrosine-protein kinase erbB-3 OS=... 158 8e-38 sp|Q61851|FGFR3_MOUSE Fibroblast growth factor receptor 3 OS=Mus ... 157 8e-38 sp|Q91285|FGFR1_PLEWA Fibroblast growth factor receptor 1 OS=Pleu... 156 1e-37 sp|Q62799|ERBB3_RAT Receptor tyrosine-protein kinase erbB-3 OS=Ra... 157 1e-37 sp|Q24488|ROR1_DROME Tyrosine-protein kinase transmembrane recept... 155 1e-37 sp|Q64725|KSYK_RAT Tyrosine-protein kinase SYK OS=Rattus norvegic... 154 1e-37 sp|Q03364|FGFR2_XENLA Fibroblast growth factor receptor 2 OS=Xeno... 156 1e-37 sp|P21860|ERBB3_HUMAN Receptor tyrosine-protein kinase erbB-3 OS=... 157 2e-37 sp|Q61526|ERBB3_MOUSE Receptor tyrosine-protein kinase erbB-3 OS=... 157 2e-37 sp|P55245|EGFR_MACMU Epidermal growth factor receptor OS=Macaca m... 157 2e-37 sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sap... 157 2e-37 sp|Q8JG38|FGFR2_DANRE Fibroblast growth factor receptor 2 OS=Dani... 155 2e-37 sp|Q01279|EGFR_MOUSE Epidermal growth factor receptor OS=Mus musc... 156 3e-37 sp|Q9I8X3|FGFR3_DANRE Fibroblast growth factor receptor 3 OS=Dani... 155 3e-37 sp|P43404|ZAP70_MOUSE Tyrosine-protein kinase ZAP-70 OS=Mus muscu... 152 4e-37 sp|G5EBZ8|ARK1_CAEEL Ack-related non-receptor tyrosine kinase OS=... 155 7e-37 sp|Q86PM4|FGFR_HYDVU Fibroblast growth factor receptor OS=Hydra v... 154 8e-37 sp|P42686|SRK1_SPOLA Tyrosine-protein kinase isoform SRK1 OS=Spon... 149 9e-37 sp|P0CY46|EGFR_APIME Epidermal growth factor receptor OS=Apis mel... 155 1e-36 sp|P17713|STK_HYDVU Tyrosine-protein kinase STK OS=Hydra vulgaris... 149 1e-36 sp|Q9H3Y6|SRMS_HUMAN Tyrosine-protein kinase Srms OS=Homo sapiens... 148 2e-36 sp|Q91743|FGFR4_XENLA Fibroblast growth factor receptor 4 OS=Xeno... 152 3e-36 sp|Q62371|DDR2_MOUSE Discoidin domain-containing receptor 2 OS=Mu... 152 3e-36 sp|Q62190|RON_MOUSE Macrophage-stimulating protein receptor OS=Mu... 153 4e-36 sp|Q62270|SRMS_MOUSE Tyrosine-protein kinase Srms OS=Mus musculus... 147 6e-36 sp|Q03145|EPHA2_MOUSE Ephrin type-A receptor 2 OS=Mus musculus OX... 151 7e-36 sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens OX... 151 8e-36 sp|P35546|RET_MOUSE Proto-oncogene tyrosine-protein kinase recept... 151 9e-36 sp|G3V9H8|RET_RAT Proto-oncogene tyrosine-protein kinase receptor... 151 9e-36 sp|P13406|FYN_XENLA Tyrosine-protein kinase Fyn OS=Xenopus laevis... 147 1e-35 sp|P00527|YES_AVISY Tyrosine-protein kinase transforming protein ... 146 1e-35 sp|P10447|ABL_FSVHY Tyrosine-protein kinase transforming protein ... 144 2e-35 sp|Q1KL86|EPHA2_MACFA Ephrin type-A receptor 2 OS=Macaca fascicul... 150 2e-35 sp|Q09YN5|MET_RABIT Hepatocyte growth factor receptor OS=Oryctola... 150 2e-35 sp|O02466|ILPR_BRALA Insulin-like peptide receptor OS=Branchiosto... 150 2e-35 sp|P16056|MET_MOUSE Hepatocyte growth factor receptor OS=Mus musc... 150 2e-35 sp|P27446|FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiphophorus he... 146 2e-35 sp|Q9VZI2|ACK_DROME Activated Cdc42 kinase Ack OS=Drosophila mela... 150 2e-35 sp|P09324|YES_CHICK Tyrosine-protein kinase Yes OS=Gallus gallus ... 146 2e-35 sp|P29321|EPHA8_RAT Ephrin type-A receptor 8 (Fragment) OS=Rattus... 142 2e-35 sp|P04412|EGFR_DROME Epidermal growth factor receptor OS=Drosophi... 150 3e-35 sp|P00521|ABL_MLVAB Tyrosine-protein kinase transforming protein ... 148 3e-35 sp|P10936|YES_XENLA Tyrosine-protein kinase Yes OS=Xenopus laevis... 145 4e-35 sp|Q90330|FGFR4_COTCO Fibroblast growth factor receptor 4 OS=Cotu... 147 4e-35 sp|Q2QLH6|MET_OTOGA Hepatocyte growth factor receptor OS=Otolemur... 150 4e-35 sp|A1A5H8|YES_DANRE Tyrosine-protein kinase yes OS=Danio rerio OX... 145 6e-35 sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens... 149 6e-35 sp|Q04912|RON_HUMAN Macrophage-stimulating protein receptor OS=Ho... 149 6e-35 sp|G5ECJ6|CSK1_CAEEL Tyrosine-protein kinase csk-1 OS=Caenorhabdi... 144 7e-35 sp|Q60553|ERBB2_MESAU Receptor tyrosine-protein kinase erbB-2 OS=... 149 7e-35 sp|Q2QLF1|MET_PANTR Hepatocyte growth factor receptor OS=Pan trog... 149 8e-35 sp|Q2IBD8|MET_PONAB Hepatocyte growth factor receptor OS=Pongo ab... 149 8e-35 sp|Q2IBF2|MET_GORGO Hepatocyte growth factor receptor OS=Gorilla ... 149 8e-35 sp|Q2IBA6|MET_CHLAE Hepatocyte growth factor receptor OS=Chloroce... 149 8e-35 sp|Q07DY1|MET_NOMLE Hepatocyte growth factor receptor OS=Nomascus... 149 8e-35 sp|P39688|FYN_MOUSE Tyrosine-protein kinase Fyn OS=Mus musculus O... 144 8e-35 sp|Q2QLC0|MET_PLEMO Hepatocyte growth factor receptor OS=Plecturo... 149 8e-35 sp|P08581|MET_HUMAN Hepatocyte growth factor receptor OS=Homo sap... 149 8e-35 sp|Q2QL89|MET_MICMU Hepatocyte growth factor receptor OS=Microceb... 149 8e-35 sp|Q2IBG7|MET_EULMM Hepatocyte growth factor receptor OS=Eulemur ... 149 8e-35 sp|A0M8R7|MET_PAPAN Hepatocyte growth factor receptor OS=Papio an... 148 8e-35 sp|Q2QLG5|MET_CALJA Hepatocyte growth factor receptor OS=Callithr... 148 9e-35 sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo sapiens O... 144 9e-35 sp|Q07DV8|MET_AOTNA Hepatocyte growth factor receptor OS=Aotus na... 148 9e-35 sp|Q09YH7|MET_SAIBB Hepatocyte growth factor receptor OS=Saimiri ... 148 1e-34 sp|Q07DZ1|MET_COLGU Hepatocyte growth factor receptor OS=Colobus ... 148 1e-34 sp|A1Y2K1|FYN_PIG Tyrosine-protein kinase Fyn OS=Sus scrofa OX=98... 144 1e-34 sp|P00520|ABL1_MOUSE Tyrosine-protein kinase ABL1 OS=Mus musculus... 148 1e-34 sp|Q09YL1|MET_ATEGE Hepatocyte growth factor receptor OS=Ateles g... 148 1e-34 sp|Q62844|FYN_RAT Tyrosine-protein kinase Fyn OS=Rattus norvegicu... 144 1e-34 sp|A0JNB0|FYN_BOVIN Tyrosine-protein kinase Fyn OS=Bos taurus OX=... 144 1e-34 sp|Q16832|DDR2_HUMAN Discoidin domain-containing receptor 2 OS=Ho... 147 1e-34 sp|P31693|SRC_RSVPA Tyrosine-protein kinase transforming protein ... 143 1e-34 sp|O18735|ERBB2_CANLF Receptor tyrosine-protein kinase erbB-2 OS=... 147 2e-34 sp|P29318|EPHA3_CHICK Ephrin type-A receptor 3 OS=Gallus gallus O... 147 2e-34 sp|Q1JPZ3|SRC_DANRE Proto-oncogene tyrosine-protein kinase Src OS... 143 2e-34 sp|Q26614|FGFR_STRPU Fibroblast growth factor receptor OS=Strongy... 147 2e-34 sp|P51813|BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX OS=Ho... 145 2e-34 sp|Q05688|IGF1R_BOVIN Insulin-like growth factor 1 receptor (Frag... 144 2e-34 sp|P06494|ERBB2_RAT Receptor tyrosine-protein kinase erbB-2 OS=Ra... 147 2e-34 sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src OS... 143 2e-34 sp|O13148|EPA4A_DANRE Ephrin type-A receptor 4a (Fragment) OS=Dan... 137 2e-34 sp|Q25410|MIPR_LYMST Putative molluscan insulin-related peptide(s... 147 2e-34 sp|P03949|ABL1_CAEEL Tyrosine-protein kinase abl-1 OS=Caenorhabdi... 147 2e-34 sp|Q09YK0|MET_MUNMU Hepatocyte growth factor receptor OS=Muntiacu... 147 2e-34 sp|Q6EWH2|FYNA_DANRE Tyrosine-protein kinase fyna OS=Danio rerio ... 143 2e-34 sp|Q2IBC0|MET_RHIFE Hepatocyte growth factor receptor OS=Rhinolop... 147 3e-34 sp|P04626|ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 OS=... 147 3e-34 sp|P51451|BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo sapiens O... 142 3e-34 sp|A1X150|MET_ECHTE Hepatocyte growth factor receptor OS=Echinops... 147 3e-34 sp|Q769I5|MET_BOVIN Hepatocyte growth factor receptor OS=Bos taur... 147 3e-34 sp|F1RDG9|FYNB_DANRE Tyrosine-protein kinase fynb OS=Danio rerio ... 142 3e-34 sp|P70424|ERBB2_MOUSE Receptor tyrosine-protein kinase erbB-2 OS=... 146 3e-34 sp|P63185|SRC_RSVSE Tyrosine-protein kinase transforming protein ... 142 3e-34 sp|P29320|EPHA3_HUMAN Ephrin type-A receptor 3 OS=Homo sapiens OX... 146 3e-34 sp|P00524|SRC_RSVSA Tyrosine-protein kinase transforming protein ... 142 4e-34 sp|Q09YI9|MET_SHEEP Hepatocyte growth factor receptor OS=Ovis ari... 146 4e-34 sp|Q00PJ8|MET_ATEAB Hepatocyte growth factor receptor OS=Atelerix... 146 4e-34 sp|Q8AXY6|MUSK_CHICK Muscle, skeletal receptor tyrosine protein k... 145 4e-34 sp|O08680|EPHA3_RAT Ephrin type-A receptor 3 OS=Rattus norvegicus... 145 5e-34 sp|Q2QLE0|MET_PIG Hepatocyte growth factor receptor OS=Sus scrofa... 146 5e-34 sp|Q9WUD9|SRC_RAT Proto-oncogene tyrosine-protein kinase Src OS=R... 142 5e-34 sp|P05480|SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src OS... 142 5e-34 sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens... 145 5e-34 sp|P54756|EPHA5_HUMAN Ephrin type-A receptor 5 OS=Homo sapiens OX... 145 6e-34 sp|P54755|EPHA5_CHICK Ephrin type-A receptor 5 OS=Gallus gallus O... 145 6e-34 sp|P42682|TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus musculus O... 141 6e-34 sp|P14084|SRC_AVISS Tyrosine-protein kinase transforming protein ... 142 6e-34 sp|P00526|SRC_RSVP Tyrosine-protein kinase transforming protein S... 141 7e-34 sp|P27447|YES_XIPHE Tyrosine-protein kinase Yes OS=Xiphophorus he... 141 7e-34 sp|P00525|SRC_AVISR Tyrosine-protein kinase transforming protein ... 141 7e-34 sp|Q8MY85|FGFR2_DUGJA Fibroblast growth factor receptor 2 OS=Duge... 144 7e-34 sp|P13115|SRC1_XENLA Tyrosine-protein kinase Src-1 OS=Xenopus lae... 141 7e-34 sp|Q2QLA9|MET_HORSE Hepatocyte growth factor receptor OS=Equus ca... 145 8e-34 sp|Q07E24|MET_MUSPF Hepatocyte growth factor receptor OS=Mustela ... 145 8e-34 sp|Q8MY86|FGFR1_DUGJA Fibroblast growth factor receptor 1 OS=Duge... 144 8e-34 sp|P29319|EPHA3_MOUSE Ephrin type-A receptor 3 OS=Mus musculus OX... 145 8e-34 sp|P00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src OS... 141 8e-34 sp|Q9YI66|TYRO3_DANRE Tyrosine-protein kinase receptor TYRO3 OS=D... 144 8e-34 sp|Q108U6|MET_LOXAF Hepatocyte growth factor receptor OS=Loxodont... 145 9e-34 sp|Q04736|YES_MOUSE Tyrosine-protein kinase Yes OS=Mus musculus O... 141 9e-34 sp|Q75ZY9|MET_CANLF Hepatocyte growth factor receptor OS=Canis lu... 145 1e-33 sp|Q07E01|MET_ORNAN Hepatocyte growth factor receptor OS=Ornithor... 145 1e-33 sp|P14085|SRC_AVIST Tyrosine-protein kinase transforming protein ... 141 1e-33 sp|P15054|SRC_AVIS2 Tyrosine-protein kinase transforming protein ... 142 1e-33 sp|Q4JIM5|ABL2_MOUSE Tyrosine-protein kinase ABL2 OS=Mus musculus... 145 1e-33 sp|Q02977|YRK_CHICK Proto-oncogene tyrosine-protein kinase Yrk OS... 141 1e-33 sp|P97523|MET_RAT Hepatocyte growth factor receptor OS=Rattus nor... 145 1e-33 sp|P07947|YES_HUMAN Tyrosine-protein kinase Yes OS=Homo sapiens O... 141 1e-33 sp|Q28923|YES_CANLF Tyrosine-protein kinase Yes OS=Canis lupus fa... 140 1e-33 sp|P13116|SRC2_XENLA Tyrosine-protein kinase Src-2 OS=Xenopus lae... 140 1e-33 sp|P54757|EPHA5_RAT Ephrin type-A receptor 5 OS=Rattus norvegicus... 144 1e-33 sp|P23049|SEA_AVIET Tyrosine-protein kinase transforming protein ... 137 2e-33 sp|Q60629|EPHA5_MOUSE Ephrin type-A receptor 5 OS=Mus musculus OX... 143 2e-33 sp|O13146|EPHA3_DANRE Ephrin type-A receptor 3 OS=Danio rerio OX=... 144 2e-33 sp|Q7YR43|DDR1_PANTR Epithelial discoidin domain-containing recep... 143 2e-33 sp|Q08345|DDR1_HUMAN Epithelial discoidin domain-containing recep... 143 2e-33 sp|P06213|INSR_HUMAN Insulin receptor OS=Homo sapiens OX=9606 GN=... 144 2e-33 sp|Q93105|INSR_AEDAE Insulin-like receptor OS=Aedes aegypti OX=71... 144 2e-33 sp|Q9I7F7|ACKL_DROME Activated Cdc42 kinase-like OS=Drosophila me... 144 2e-33 sp|P97504|BMX_MOUSE Cytoplasmic tyrosine-protein kinase BMX OS=Mu... 141 2e-33 sp|Q07E48|MET_DASNO Hepatocyte growth factor receptor OS=Dasypus ... 144 2e-33 sp|P33497|RYK_AVIR3 Tyrosine-protein kinase transforming protein ... 138 2e-33 sp|Q02858|TIE2_MOUSE Angiopoietin-1 receptor OS=Mus musculus OX=1... 143 2e-33 sp|P16277|BLK_MOUSE Tyrosine-protein kinase Blk OS=Mus musculus O... 139 2e-33 sp|Q06807|TIE2_BOVIN Angiopoietin-1 receptor OS=Bos taurus OX=991... 143 3e-33 sp|Q06806|TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mu... 143 3e-33 sp|P21709|EPHA1_HUMAN Ephrin type-A receptor 1 OS=Homo sapiens OX... 143 3e-33 sp|Q02763|TIE2_HUMAN Angiopoietin-1 receptor OS=Homo sapiens OX=9... 143 3e-33 sp|Q10656|EGL15_CAEEL Myoblast growth factor receptor egl-15 OS=C... 143 3e-33 sp|O76997|TRK1_LYMST Putative neurotrophin receptor LTRK 1 OS=Lym... 142 3e-33 sp|Q9PVZ4|INSR_XENLA Insulin receptor OS=Xenopus laevis OX=8355 G... 143 4e-33 sp|O15146|MUSK_HUMAN Muscle, skeletal receptor tyrosine-protein k... 142 4e-33 sp|Q07E37|MET_NEONE Hepatocyte growth factor receptor OS=Neofelis... 143 4e-33 sp|A0M8S8|MET_FELCA Hepatocyte growth factor receptor OS=Felis ca... 143 4e-33 sp|O45539|SRC2_CAEEL Tyrosine protein-kinase src-2 OS=Caenorhabdi... 138 5e-33 sp|Q95ZV7|DDRB_CAEEL Discoidin domain-containing receptor tyrosin... 141 5e-33 sp|Q4H3K6|FGFR_CIOIN Fibroblast growth factor receptor OS=Ciona i... 140 7e-33 sp|F1LM93|YES_RAT Tyrosine-protein kinase Yes OS=Rattus norvegicu... 138 8e-33 sp|Q95YM9|FGFR_HALRO Fibroblast growth factor receptor OS=Halocyn... 140 9e-33 sp|Q12866|MERTK_HUMAN Tyrosine-protein kinase Mer OS=Homo sapiens... 141 9e-33 sp|O42422|EPHA7_CHICK Ephrin type-A receptor 7 OS=Gallus gallus O... 141 1e-32 sp|O09127|EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus musculus OX... 141 1e-32 sp|P25020|SRC_RSVH1 Tyrosine-protein kinase transforming protein ... 137 1e-32 sp|P35590|TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 OS=Ho... 141 1e-32 sp|P00528|SRC64_DROME Tyrosine-protein kinase Src64B OS=Drosophil... 138 1e-32 sp|O73798|IGF1R_XENLA Insulin-like growth factor 1 receptor OS=Xe... 141 1e-32 sp|Q63474|DDR1_RAT Epithelial discoidin domain-containing recepto... 140 1e-32 sp|P08069|IGF1R_HUMAN Insulin-like growth factor 1 receptor OS=Ho... 141 1e-32 sp|Q13308|PTK7_HUMAN Inactive tyrosine-protein kinase 7 OS=Homo s... 141 1e-32 sp|P24062|IGF1R_RAT Insulin-like growth factor 1 receptor OS=Ratt... 141 2e-32 sp|Q15375|EPHA7_HUMAN Ephrin type-A receptor 7 OS=Homo sapiens OX... 140 2e-32 sp|P54759|EPHA7_RAT Ephrin type-A receptor 7 OS=Rattus norvegicus... 140 2e-32 sp|Q9VBW3|CAD96_DROME Tyrosine kinase receptor Cad96Ca OS=Drosoph... 139 2e-32 sp|Q06805|TIE1_BOVIN Tyrosine-protein kinase receptor Tie-1 OS=Bo... 140 2e-32 sp|Q60751|IGF1R_MOUSE Insulin-like growth factor 1 receptor OS=Mu... 141 2e-32 sp|Q8BKG3|PTK7_MOUSE Inactive tyrosine-protein kinase 7 OS=Mus mu... 140 2e-32 sp|P14617|INSRR_CAVPO Insulin receptor-related protein OS=Cavia p... 140 2e-32 sp|Q64434|PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus musculus OX... 134 4e-32 sp|P18106|FER_DROME Tyrosine-protein kinase Fer OS=Drosophila mel... 140 4e-32 sp|Q61772|EPHA7_MOUSE Ephrin type-A receptor 7 OS=Mus musculus OX... 139 4e-32 sp|P00541|FPS_AVISP Tyrosine-protein kinase transforming protein ... 135 5e-32 sp|Q9TTY2|FER_CANLF Tyrosine-protein kinase Fer OS=Canis lupus fa... 138 5e-32 sp|Q60805|MERTK_MOUSE Tyrosine-protein kinase Mer OS=Mus musculus... 139 6e-32 sp|Q91845|EPA4A_XENLA Ephrin type-A receptor 4-A OS=Xenopus laevi... 139 6e-32 sp|O73791|TIE2_DANRE Angiopoietin-1 receptor OS=Danio rerio OX=79... 139 6e-32 sp|Q07496|EPHA4_CHICK Ephrin type-A receptor 4 OS=Gallus gallus O... 139 7e-32 sp|Q60750|EPHA1_MOUSE Ephrin type-A receptor 1 OS=Mus musculus OX... 138 7e-32 sp|Q62838|MUSK_RAT Muscle, skeletal receptor tyrosine protein kin... 138 8e-32 sp|Q03137|EPHA4_MOUSE Ephrin type-A receptor 4 OS=Mus musculus OX... 138 1e-31 sp|Q03146|DDR1_MOUSE Epithelial discoidin domain-containing recep... 137 1e-31 sp|P54764|EPHA4_HUMAN Ephrin type-A receptor 4 OS=Homo sapiens OX... 137 1e-31 sp|P29322|EPHA8_HUMAN Ephrin type-A receptor 8 OS=Homo sapiens OX... 137 1e-31 sp|P00529|ROS_AVISU Tyrosine-protein kinase transforming protein ... 132 1e-31 sp|Q61006|MUSK_MOUSE Muscle, skeletal receptor tyrosine-protein k... 137 2e-31 sp|Q91694|EPA4B_XENLA Ephrin type-A receptor 4-B OS=Xenopus laevi... 137 2e-31 sp|H2KZU7|SVH2_CAEEL Tyrosine-protein kinase receptor svh-2 OS=Ca... 137 2e-31 sp|P08630|BTKL_DROME Tyrosine-protein kinase Btk OS=Drosophila me... 136 2e-31 sp|Q54I36|PYK3_DICDI Dual specificity protein kinase pyk3 OS=Dict... 137 3e-31 sp|P15127|INSR_RAT Insulin receptor OS=Rattus norvegicus OX=10116... 137 3e-31 sp|P15208|INSR_MOUSE Insulin receptor OS=Mus musculus OX=10090 GN... 137 3e-31 sp|P42687|SPK1_GIRTI Tyrosine-protein kinase SPK-1 OS=Girardia ti... 133 3e-31 sp|P57097|MERTK_RAT Tyrosine-protein kinase Mer OS=Rattus norvegi... 136 3e-31 sp|Q63132|ROS1_RAT Proto-oncogene tyrosine-protein kinase ROS OS=... 137 4e-31 sp|Q64716|INSRR_RAT Insulin receptor-related protein OS=Rattus no... 136 4e-31 sp|Q06187|BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo sapiens O... 134 4e-31 sp|P13368|7LESS_DROME Protein sevenless OS=Drosophila melanogaste... 137 4e-31 sp|Q25197|HTK7_HYDVU Putative insulin-like peptide receptor OS=Hy... 136 4e-31 sp|Q78DX7|ROS1_MOUSE Proto-oncogene tyrosine-protein kinase ROS O... 137 5e-31 sp|P09760|FER_RAT Tyrosine-protein kinase Fer OS=Rattus norvegicu... 135 5e-31 sp|P20806|7LESS_DROVI Protein sevenless OS=Drosophila virilis OX=... 137 5e-31 sp|Q9WTL4|INSRR_MOUSE Insulin receptor-related protein OS=Mus mus... 135 7e-31 sp|P70451|FER_MOUSE Tyrosine-protein kinase Fer OS=Mus musculus O... 135 7e-31 sp|P09208|INSR_DROME Insulin-like receptor OS=Drosophila melanoga... 136 7e-31 sp|G5EGK5|CAM1_CAEEL Tyrosine-protein kinase receptor cam-1 OS=Ca... 135 9e-31 sp|P14616|INSRR_HUMAN Insulin receptor-related protein OS=Homo sa... 135 1e-30 sp|Q05876|FYN_CHICK Tyrosine-protein kinase Fyn OS=Gallus gallus ... 132 1e-30 sp|Q10925|SID3_CAEEL Tyrosine-protein kinase sid-3 OS=Caenorhabdi... 134 2e-30 sp|P42681|TXK_HUMAN Tyrosine-protein kinase TXK OS=Homo sapiens O... 131 2e-30 sp|P00530|FPS_FUJSV Tyrosine-protein kinase transforming protein ... 134 2e-30 sp|Q6P6U0|FGR_RAT Tyrosine-protein kinase Fgr OS=Rattus norvegicu... 130 2e-30 sp|P00542|FES_FSVGA Tyrosine-protein kinase transforming protein ... 132 2e-30 sp|Q968Y9|INSR_CAEEL Insulin-like receptor OS=Caenorhabditis eleg... 134 3e-30 sp|P35991|BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus musculus O... 132 3e-30 sp|Q98949|TYRO3_CHICK Tyrosine-protein kinase receptor TYRO3 OS=G... 133 3e-30 sp|Q9Z139|ROR1_MOUSE Inactive tyrosine-protein kinase transmembra... 133 4e-30 sp|Q01973|ROR1_HUMAN Inactive tyrosine-protein kinase transmembra... 133 4e-30 sp|Q99ML2|TNK1_MOUSE Non-receptor tyrosine-protein kinase TNK1 OS... 131 4e-30 sp|P00543|FES_FSVST Tyrosine-protein kinase transforming protein ... 129 5e-30 sp|P14234|FGR_MOUSE Tyrosine-protein kinase Fgr OS=Mus musculus O... 129 6e-30 sp|G5EE56|SRC1_CAEEL Tyrosine protein-kinase src-1 OS=Caenorhabdi... 129 7e-30 sp|P42680|TEC_HUMAN Tyrosine-protein kinase Tec OS=Homo sapiens O... 130 8e-30 sp|Q13470|TNK1_HUMAN Non-receptor tyrosine-protein kinase TNK1 OS... 130 1e-29 sp|P08922|ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS O... 132 1e-29 sp|Q8CBF3|EPHB1_MOUSE Ephrin type-B receptor 1 OS=Mus musculus OX... 131 1e-29 sp|P09759|EPHB1_RAT Ephrin type-B receptor 1 OS=Rattus norvegicus... 131 1e-29 sp|P09769|FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo sapiens O... 128 1e-29 sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo sapiens OX... 131 2e-29 sp|Q91736|EPB1B_XENLA Ephrin type-B receptor 1-B (Fragment) OS=Xe... 130 2e-29 sp|Q91048|PTK7_CHICK Inactive tyrosine-protein kinase 7 OS=Gallus... 130 2e-29 sp|P14238|FES_FELCA Tyrosine-protein kinase Fes/Fps OS=Felis catu... 130 2e-29 sp|Q22146|FRK1_CAEEL Fer-related kinase 1 OS=Caenorhabditis elega... 125 3e-29 sp|Q8BYG9|EPHAA_MOUSE Ephrin type-A receptor 10 OS=Mus musculus O... 130 3e-29 sp|A0JM20|TYRO3_XENTR Tyrosine-protein kinase receptor TYRO3 OS=X... 130 3e-29 sp|P16591|FER_HUMAN Tyrosine-protein kinase Fer OS=Homo sapiens O... 129 3e-29 sp|Q91735|EPHB3_XENLA Ephrin type-B receptor 3 OS=Xenopus laevis ... 129 4e-29 sp|P24348|LET23_CAEEL Receptor tyrosine-protein kinase let-23 OS=... 130 4e-29 sp|Q2MHE4|HT1_ARATH Serine/threonine/tyrosine-protein kinase HT1 ... 124 4e-29 sp|Q9UF33|EPHA6_HUMAN Ephrin type-A receptor 6 OS=Homo sapiens OX... 129 6e-29 sp|P07332|FES_HUMAN Tyrosine-protein kinase Fes/Fps OS=Homo sapie... 129 6e-29 sp|Q07494|EPHB1_CHICK Ephrin type-B receptor 1 (Fragment) OS=Gall... 129 6e-29 sp|P54758|EPHA6_RAT Ephrin type-A receptor 6 OS=Rattus norvegicus... 129 6e-29 sp|P00544|FGR_FSVGR Tyrosine-protein kinase transforming protein ... 126 6e-29 sp|P24604|TEC_MOUSE Tyrosine-protein kinase Tec OS=Mus musculus O... 127 7e-29 sp|Q19238|YS3J_CAEEL Putative tyrosine-protein kinase F09A5.2 OS=... 128 7e-29 sp|P54763|EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus musculus OX... 129 7e-29 sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens OX... 129 9e-29 sp|P55146|TYRO3_RAT Tyrosine-protein kinase receptor TYRO3 OS=Rat... 128 9e-29 sp|Q13882|PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo sapiens OX... 124 1e-28 sp|P28693|EPHB2_CHICK Ephrin type-B receptor 2 OS=Gallus gallus O... 128 1e-28 sp|P29376|LTK_HUMAN Leukocyte tyrosine kinase receptor OS=Homo sa... 127 1e-28 sp|Q8JH64|BTK_CHICK Tyrosine-protein kinase BTK OS=Gallus gallus ... 126 1e-28 sp|Q62413|EPHA6_MOUSE Ephrin type-A receptor 6 OS=Mus musculus OX... 128 2e-28 sp|P55144|TYRO3_MOUSE Tyrosine-protein kinase receptor TYRO3 OS=M... 127 2e-28 sp|D2IYS2|TORSO_BOMMO Tyrosine-protein kinase receptor torso OS=B... 127 2e-28 sp|P16879|FES_MOUSE Tyrosine-protein kinase Fes/Fps OS=Mus muscul... 127 2e-28 sp|P08941|ROS1_CHICK Proto-oncogene tyrosine-protein kinase ROS O... 128 2e-28 sp|Q06418|TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3 OS=H... 127 2e-28 sp|Q90344|EPHB2_COTJA Ephrin type-B receptor 2 OS=Coturnix japoni... 127 2e-28 sp|Q54TM7|DRKD_DICDI Probable serine/threonine-protein kinase drk... 127 3e-28 sp|Q8QFP9|TYRO3_XENLA Tyrosine-protein kinase receptor TYRO3 OS=X... 126 4e-28 sp|Q03526|ITK_MOUSE Tyrosine-protein kinase ITK/TSK OS=Mus muscul... 125 4e-28 sp|P18475|TORSO_DROME Tyrosine-protein kinase receptor torso OS=D... 126 4e-28 sp|Q01887|RYK_MOUSE Tyrosine-protein kinase RYK OS=Mus musculus O... 124 5e-28 sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kinas... 125 5e-28 sp|Q91571|EPB1A_XENLA Ephrin type-B receptor 1-A OS=Xenopus laevi... 126 5e-28 sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase kin... 125 5e-28 sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kin... 125 6e-28 sp|O13147|EPHB3_DANRE Ephrin type-B receptor 3 (Fragment) OS=Dani... 122 7e-28 sp|Q9I8N6|CSF1R_DANRE Macrophage colony-stimulating factor 1 rece... 125 8e-28 sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens OX... 125 8e-28 sp|O73878|EPB4B_DANRE Ephrin type-B receptor 4b OS=Danio rerio OX... 125 1e-27 sp|P30530|UFO_HUMAN Tyrosine-protein kinase receptor UFO OS=Homo ... 125 1e-27 sp|O73792|TIE1_DANRE Tyrosine-protein kinase receptor Tie-1 (Frag... 114 1e-27 sp|P97793|ALK_MOUSE ALK tyrosine kinase receptor OS=Mus musculus ... 125 1e-27 sp|Q5JZY3|EPHAA_HUMAN Ephrin type-A receptor 10 OS=Homo sapiens O... 124 1e-27 sp|O73875|EPB4A_DANRE Ephrin type-B receptor 4a OS=Danio rerio OX... 124 1e-27 sp|P08923|LTK_MOUSE Leukocyte tyrosine kinase receptor OS=Mus mus... 124 1e-27 sp|P54761|EPHB4_MOUSE Ephrin type-B receptor 4 OS=Mus musculus OX... 124 2e-27 sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kina... 123 2e-27 sp|Q00993|UFO_MOUSE Tyrosine-protein kinase receptor UFO OS=Mus m... 124 2e-27 sp|P34925|RYK_HUMAN Tyrosine-protein kinase RYK OS=Homo sapiens O... 122 2e-27 sp|Q07497|EPHB5_CHICK Ephrin type-B receptor 5 OS=Gallus gallus O... 124 2e-27 sp|Q9UM73|ALK_HUMAN ALK tyrosine kinase receptor OS=Homo sapiens ... 124 2e-27 sp|Q61084|M3K3_MOUSE Mitogen-activated protein kinase kinase kina... 122 2e-27 sp|P0DV84|ALK_CANLF ALK tyrosine kinase receptor OS=Canis lupus f... 124 2e-27 sp|P80192|M3K9_HUMAN Mitogen-activated protein kinase kinase kina... 124 3e-27 sp|O22558|STY8_ARATH Serine/threonine-protein kinase STY8 OS=Arab... 120 5e-27 sp|Q66L42|M3K10_MOUSE Mitogen-activated protein kinase kinase kin... 122 6e-27 sp|P04048|KIT_FSVHZ Tyrosine-protein kinase transforming protein ... 117 6e-27 sp|P54753|EPHB3_HUMAN Ephrin type-B receptor 3 OS=Homo sapiens OX... 122 7e-27 sp|Q08881|ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=Homo sapie... 121 7e-27 sp|Q3U1V8|M3K9_MOUSE Mitogen-activated protein kinase kinase kina... 122 9e-27 sp|P54754|EPHB3_MOUSE Ephrin type-B receptor 3 OS=Mus musculus OX... 122 9e-27 sp|D3ZG83|M3K10_RAT Mitogen-activated protein kinase kinase kinas... 122 9e-27 sp|Q07498|EPHB3_CHICK Ephrin type-B receptor 3 (Fragment) OS=Gall... 122 1e-26 sp|Q21038|VER3_CAEEL Tyrosine-protein kinase receptor ver-3 OS=Ca... 122 1e-26 sp|Q17833|OLD1_CAEEL Tyrosine-protein kinase receptor old-1 OS=Ca... 119 2e-26 sp|F4JTP5|STY46_ARATH Serine/threonine-protein kinase STY46 OS=Ar... 119 2e-26 sp|P34892|KIN16_CAEEL Receptor-like tyrosine-protein kinase kin-1... 118 2e-26 sp|Q5XF79|PBL18_ARATH Probable serine/threonine-protein kinase PB... 116 3e-26 sp|Q02779|M3K10_HUMAN Mitogen-activated protein kinase kinase kin... 120 3e-26 sp|Q01974|ROR2_HUMAN Tyrosine-protein kinase transmembrane recept... 120 3e-26 sp|Q54PX0|Y4251_DICDI Probable serine/threonine-protein kinase DD... 117 6e-26 sp|Q08156|KIT_CHICK Mast/stem cell growth factor receptor Kit OS=... 119 7e-26 sp|Q9Z138|ROR2_MOUSE Tyrosine-protein kinase transmembrane recept... 119 8e-26 sp|Q9V6K3|ROR2_DROME Tyrosine-protein kinase transmembrane recept... 117 1e-25 sp|O76411|SCD2_CAEEL ALK tyrosine kinase receptor homolog scd-2 O... 118 2e-25 sp|Q28889|KIT_FELCA Mast/stem cell growth factor receptor Kit OS=... 117 2e-25 sp|P43481|KIT_BOVIN Mast/stem cell growth factor receptor Kit OS=... 117 2e-25 sp|Q28317|KIT_CAPHI Mast/stem cell growth factor receptor Kit OS=... 117 2e-25 sp|O97799|KIT_CANLF Mast/stem cell growth factor receptor Kit OS=... 117 2e-25 sp|Q2HWD6|KIT_PIG Mast/stem cell growth factor receptor Kit OS=Su... 117 3e-25 sp|G4N7X0|MST11_PYRO7 Mitogen-activated protein kinase kinae kina... 117 3e-25 sp|P10721|KIT_HUMAN Mast/stem cell growth factor receptor Kit OS=... 117 3e-25 sp|Q76II0|KIT_CALJA Mast/stem cell growth factor receptor Kit OS=... 117 3e-25 sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kina... 115 3e-25 sp|P05532|KIT_MOUSE Mast/stem cell growth factor receptor Kit OS=... 117 4e-25 sp|O61460|VAB1_CAEEL Ephrin receptor 1 OS=Caenorhabditis elegans ... 117 4e-25 sp|Q8RWL6|STY17_ARATH Serine/threonine-protein kinase STY17 OS=Ar... 115 4e-25 sp|F8W3R9|ALK_DANRE ALK tyrosine kinase receptor OS=Danio rerio O... 117 5e-25 sp|P00545|KFMS_FSVMD Tyrosine-protein kinase transforming protein... 116 5e-25 sp|Q5MD89|VGFR3_DANRE Vascular endothelial growth factor receptor... 117 5e-25 sp|A9SY39|M3K1A_PHYPA Mitogen-activated protein kinase kinase kin... 115 5e-25 sp|P13369|CSF1R_FELCA Macrophage colony-stimulating factor 1 rece... 115 8e-25 sp|P07333|CSF1R_HUMAN Macrophage colony-stimulating factor 1 rece... 115 8e-25 sp|P42159|RTK2_GEOCY Class II receptor tyrosine kinase OS=Geodia ... 114 9e-25 sp|Q9FGB1|CBC2_ARATH Serine/threonine-protein kinase 52 OS=Arabid... 111 9e-25 sp|Q55GU0|Y9955_DICDI Probable serine/threonine-protein kinase DD... 115 9e-25 sp|Q5PP29|PBL4_ARATH Probable serine/threonine-protein kinase PBL... 112 9e-25 sp|Q9ZQ31|STY13_ARATH Serine/threonine-protein kinase STY13 OS=Ar... 111 2e-24 sp|Q9ESL4|M3K20_MOUSE Mitogen-activated protein kinase kinase kin... 114 2e-24 sp|Q9SFB6|M3KE2_ARATH MAP3K epsilon protein kinase 2 OS=Arabidops... 115 2e-24 sp|Q9NYL2|M3K20_HUMAN Mitogen-activated protein kinase kinase kin... 114 2e-24 sp|F1QVU0|LTK_DANRE Tyrosine-protein kinase receptor OS=Danio rer... 115 2e-24 sp|Q91909|KIT_XENLA Mast/stem cell growth factor receptor-related... 114 2e-24 sp|Q7T2V3|M3K10_XENLA Mitogen-activated protein kinase kinase kin... 114 3e-24 sp|Q00495|CSF1R_RAT Macrophage colony-stimulating factor 1 recept... 114 3e-24 sp|P27450|CST_ARATH Probable serine/threonine-protein kinase CST ... 110 3e-24 sp|Q9LJD8|M3KE1_ARATH MAP3K epsilon protein kinase 1 OS=Arabidops... 114 3e-24 sp|P09581|CSF1R_MOUSE Macrophage colony-stimulating factor 1 rece... 113 4e-24 sp|P35968|VGFR2_HUMAN Vascular endothelial growth factor receptor... 114 4e-24 sp|Q8AXC6|KIT_TAKRU Mast/stem cell growth factor receptor Kit OS=... 113 5e-24 sp|Q21041|VER4_CAEEL Tyrosine-protein kinase receptor ver-4 OS=Ca... 113 5e-24 sp|Q8JFR5|KITA_DANRE Mast/stem cell growth factor receptor kita O... 113 6e-24 sp|Q8UVR8|CSF12_TAKRU Macrophage colony-stimulating factor 1 rece... 113 6e-24 sp|Q5XJV6|LMTK3_MOUSE Serine/threonine-protein kinase LMTK3 OS=Mu... 113 7e-24 sp|A0A078CGE6|M3KE1_BRANA MAP3K epsilon protein kinase 1 OS=Brass... 113 8e-24 sp|P34891|KIN15_CAEEL Receptor-like tyrosine-protein kinase kin-1... 110 8e-24 sp|Q9SSA4|CBC1_ARATH Serine/threonine-protein kinase 54 OS=Arabid... 108 1e-23 sp|Q65XV8|RK176_ORYSJ Receptor-like cytoplasmic kinase 176 OS=Ory... 108 1e-23 sp|Q54R82|MKKA_DICDI Mitogen-activated protein kinase kinase kina... 112 1e-23 sp|F4HRJ4|M3K3A_ARATH Mitogen-activated protein kinase kinase kin... 110 2e-23 sp|Q95UN8|M3KSL_DROME Mitogen-activated protein kinase kinase kin... 112 2e-23 sp|Q8AXB3|VGFR4_DANRE Vascular endothelial growth factor receptor... 111 2e-23 sp|Q0CL79|SEPH_ASPTN Cytokinesis protein sepH OS=Aspergillus terr... 111 2e-23 sp|Q9FZ36|M3K2_ARATH Mitogen-activated protein kinase kinase kina... 110 2e-23 sp|Q61083|M3K2_MOUSE Mitogen-activated protein kinase kinase kina... 110 2e-23 sp|Q96Q04|LMTK3_HUMAN Serine/threonine-protein kinase LMTK3 OS=Ho... 111 2e-23 sp|Q54Y55|SHKC_DICDI Dual specificity protein kinase shkC OS=Dict... 108 3e-23 sp|P52583|VGFR2_COTJA Vascular endothelial growth factor receptor... 111 3e-23 sp|P41892|CDC7_SCHPO Cell division control protein 7 OS=Schizosac... 110 3e-23 sp|Q9ASQ5|CRCK3_ARATH Calmodulin-binding receptor-like cytoplasmi... 108 4e-23 sp|Q40541|NPK1_TOBAC Mitogen-activated protein kinase kinase kina... 109 4e-23 sp|P28829|BYR2_SCHPO Protein kinase byr2 OS=Schizosaccharomyces p... 109 4e-23 sp|P79750|CSF11_TAKRU Macrophage colony-stimulating factor 1 rece... 110 5e-23 sp|Q9PUF6|PGFRA_CHICK Platelet-derived growth factor receptor alp... 109 7e-23 sp|P35918|VGFR2_MOUSE Vascular endothelial growth factor receptor... 109 1e-22 sp|Q8VDG6|M3K21_MOUSE Mitogen-activated protein kinase kinase kin... 108 1e-22 sp|P79701|VGFR3_COTCO Vascular endothelial growth factor receptor... 109 1e-22 sp|P20786|PGFRA_RAT Platelet-derived growth factor receptor alpha... 108 1e-22 sp|Q9CAD5|YODA_ARATH Mitogen-activated protein kinase kinase kina... 108 1e-22 sp|P26618|PGFRA_MOUSE Platelet-derived growth factor receptor alp... 108 2e-22 sp|P16234|PGFRA_HUMAN Platelet-derived growth factor receptor alp... 108 2e-22 sp|Q39008|M3K1_ARATH Mitogen-activated protein kinase kinase kina... 107 2e-22 sp|H2L099|GCK1_CAEEL Germinal center kinase 1 OS=Caenorhabditis e... 107 3e-22 sp|E9Q3S4|M3K19_MOUSE Mitogen-activated protein kinase kinase kin... 108 3e-22 sp|A0A0K3AV08|MLK1_CAEEL Mitogen-activated protein kinase kinase ... 107 3e-22 sp|Q13546|RIPK1_HUMAN Receptor-interacting serine/threonine-prote... 106 3e-22 sp|O64842|PBL12_ARATH Probable serine/threonine-protein kinase PB... 104 3e-22 sp|Q9LTC0|PBL19_ARATH Probable serine/threonine-protein kinase PB... 104 3e-22 sp|P26619|PGFRA_XENLA Platelet-derived growth factor receptor alp... 107 4e-22 sp|P36888|FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 O... 107 4e-22 sp|Q5TCX8|M3K21_HUMAN Mitogen-activated protein kinase kinase kin... 107 4e-22 sp|Q9LFP7|PBL34_ARATH Serine/threonine-protein kinase PBL34 OS=Ar... 105 5e-22 sp|A2QHV0|SEPH_ASPNC Cytokinesis protein sepH OS=Aspergillus nige... 107 5e-22 sp|Q54RR9|Y9844_DICDI Probable serine/threonine-protein kinase DD... 107 6e-22 sp|Q8AXC7|PGFRA_TAKRU Platelet-derived growth factor receptor alp... 106 6e-22 sp|Q8VYG0|LRL13_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 105 6e-22 sp|Q5GIT4|VGFR2_DANRE Vascular endothelial growth factor receptor... 107 6e-22 sp|Q8IR79|LIMK1_DROME LIM domain kinase 1 OS=Drosophila melanogas... 106 8e-22 sp|O14047|PPK11_SCHPO Serine/threonine-protein kinase ppk11 OS=Sc... 101 8e-22 sp|Q8QHL3|VGFR1_CHICK Vascular endothelial growth factor receptor... 106 1e-21 sp|Q54RZ7|Y1199_DICDI Probable serine/threonine-protein kinase DD... 106 1e-21 sp|Q5B4Z3|SEPH_EMENI Cytokinesis protein sepH OS=Emericella nidul... 106 1e-21 sp|Q9SRH7|PBL35_ARATH Serine/threonine-protein kinase PBL35 OS=Ar... 103 1e-21 sp|P53767|VGFR1_RAT Vascular endothelial growth factor receptor 1... 105 1e-21 sp|O22042|M3K3_ARATH Mitogen-activated protein kinase kinase kina... 104 1e-21 sp|P35969|VGFR1_MOUSE Vascular endothelial growth factor receptor... 105 1e-21 sp|O01798|SPE8_CAEEL Spermatocyte protein spe-8 OS=Caenorhabditis... 103 1e-21 sp|Q55A09|Y9963_DICDI Probable serine/threonine-protein kinase DD... 105 1e-21 sp|P10533|RMIL_AVII1 Serine/threonine-protein kinase-transforming... 101 1e-21 sp|Q4WXY0|BCK1_ASPFU Mitogen-activated protein kinase kinae kinas... 105 2e-21 sp|Q8I7I5|ROL3_CAEEL Protein roller-3 OS=Caenorhabditis elegans O... 105 2e-21 sp|B0XXN8|BCK1_ASPFC Mitogen-activated protein kinase kinae kinas... 105 2e-21 sp|Q9DE49|PGFRA_DANRE Platelet-derived growth factor receptor alp... 105 2e-21 sp|P23561|STE11_YEAST Serine/threonine-protein kinase STE11 OS=Sa... 104 2e-21 sp|A7A1P0|STE11_YEAS7 Serine/threonine-protein kinase STE11 OS=Sa... 104 2e-21 sp|Q61846|MELK_MOUSE Maternal embryonic leucine zipper kinase OS=... 103 2e-21 sp|Q54H45|DRKB_DICDI Probable serine/threonine-protein kinase drk... 104 2e-21 sp|O24527|SIK1_ARATH Serine/threonine-protein kinase 1 OS=Arabido... 104 2e-21 sp|O08775|VGFR2_RAT Vascular endothelial growth factor receptor 2... 105 2e-21 sp|Q54RB7|SHKA_DICDI Dual specificity protein kinase shkA OS=Dict... 103 2e-21 sp|P35917|VGFR3_MOUSE Vascular endothelial growth factor receptor... 104 3e-21 sp|Q91ZT1|VGFR3_RAT Vascular endothelial growth factor receptor 3... 104 3e-21 sp|Q10056|SHK2_SCHPO Serine/threonine-protein kinase shk2 OS=Schi... 103 3e-21 sp|Q55FT4|TSUA_DICDI Probable serine/threonine-protein kinase tsu... 105 3e-21 sp|P27636|CDC15_YEAST Cell division control protein 15 OS=Sacchar... 104 3e-21 sp|Q00342|FLT3_MOUSE Receptor-type tyrosine-protein kinase FLT3 O... 104 3e-21 sp|P00532|RAF_MSV36 Serine/threonine-protein kinase-transforming ... 99.8 3e-21 sp|F4JPX3|PBL20_ARATH Probable serine/threonine-protein kinase PB... 100 3e-21 sp|B5VNQ3|STE11_YEAS6 Serine/threonine-protein kinase STE11 OS=Sa... 103 3e-21 sp|Q9SII6|PIX13_ARATH Probable serine/threonine-protein kinase PI... 101 4e-21 sp|Q12852|M3K12_HUMAN Mitogen-activated protein kinase kinase kin... 103 4e-21 sp|Q60700|M3K12_MOUSE Mitogen-activated protein kinase kinase kin... 103 4e-21 sp|P17948|VGFR1_HUMAN Vascular endothelial growth factor receptor... 104 4e-21 sp|A7J1T2|M313A_XENLA Mitogen-activated protein kinase kinase kin... 103 4e-21 sp|P00531|MIL_AVIMH Serine/threonine-protein kinase-transforming ... 100 4e-21 sp|Q8GXZ3|PBL8_ARATH Probable serine/threonine-protein kinase PBL... 100 5e-21 sp|P11346|KRAF1_DROME Raf homolog serine/threonine-protein kinase... 103 5e-21 sp|O22040|ANP1_ARATH Mitogen-activated protein kinase kinase kina... 102 6e-21 sp|Q7T6Y2|YR831_MIMIV Putative serine/threonine-protein kinase/re... 103 6e-21 sp|A7J1T0|M313B_XENLA Mitogen-activated protein kinase kinase kin... 103 6e-21 sp|P27966|RMIL_AVEVR Serine/threonine-protein kinase-transforming... 100 6e-21 sp|G4NDR3|MCK1_PYRO7 Mitogen-activated protein kinase kinae kinas... 103 7e-21 sp|O49840|PBL3_ARATH Probable serine/threonine-protein kinase PBL... 100 7e-21 sp|Q06548|PBL9_ARATH Probable serine/threonine-protein kinase PBL... 100 7e-21 sp|Q54TA3|MRKC_DICDI Probable serine/threonine-protein kinase MAR... 102 9e-21 sp|Q9C9U5|SIS8_ARATH Probable serine/threonine-protein kinase SIS... 102 9e-21 sp|F4J0D2|PBL36_ARATH Serine/threonine-protein kinase PBL36 OS=Ar... 100 1e-20 sp|Q9LPQ3|M2K7_ARATH Mitogen-activated protein kinase kinase 7 OS... 97.8 1e-20 sp|Q63796|M3K12_RAT Mitogen-activated protein kinase kinase kinas... 102 1e-20 sp|O48814|BIK1_ARATH Serine/threonine-protein kinase BIK1 OS=Arab... 99.4 1e-20 sp|Q8IWU2|LMTK2_HUMAN Serine/threonine-protein kinase LMTK2 OS=Ho... 102 1e-20 sp|O81472|MP3K2_ARATH Mitogen-activated protein kinase kinase kin... 102 1e-20 sp|Q9UL54|TAOK2_HUMAN Serine/threonine-protein kinase TAO2 OS=Hom... 102 1e-20 sp|Q56UN5|M3K19_HUMAN Mitogen-activated protein kinase kinase kin... 102 1e-20 sp|P11345|RAF1_RAT RAF proto-oncogene serine/threonine-protein ki... 101 1e-20 sp|Q869T7|PAKF_DICDI Serine/threonine-protein kinase pakF OS=Dict... 102 2e-20 sp|P05625|RAF1_CHICK RAF proto-oncogene serine/threonine-protein ... 101 2e-20 sp|Q6ZQ29|TAOK2_MOUSE Serine/threonine-protein kinase TAO2 OS=Mus... 102 2e-20 sp|Q5R5M7|RAF1_PONAB RAF proto-oncogene serine/threonine-protein ... 100 2e-20 sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein ... 100 2e-20 sp|Q9C5H5|M3K5G_ARATH Mitogen-activated protein kinase kinase kin... 101 2e-20 sp|A7MBB4|M3K13_BOVIN Mitogen-activated protein kinase kinase kin... 101 2e-20 sp|Q54JG7|DST4_DICDI Serine/threonine-protein kinase dst4 OS=Dict... 99.8 2e-20 sp|Q9JLS3|TAOK2_RAT Serine/threonine-protein kinase TAO2 OS=Rattu... 101 2e-20 sp|P20792|DAF1_CAEEL Cell surface receptor daf-1 OS=Caenorhabditi... 100 3e-20 sp|Q1HKZ5|M3K13_MOUSE Mitogen-activated protein kinase kinase kin... 101 3e-20 sp|Q54XQ2|RCKA_DICDI RGS domain-containing serine/threonine-prote... 101 3e-20 sp|O14305|SID1_SCHPO Serine/threonine-protein kinase sid1 OS=Schi... 99.4 3e-20 sp|P43293|PBL11_ARATH Probable serine/threonine-protein kinase PB... 98.2 3e-20 sp|A7E3S4|RAF1_BOVIN RAF proto-oncogene serine/threonine-protein ... 100 3e-20 sp|Q54TA1|DRKC_DICDI Probable serine/threonine-protein kinase drk... 100 3e-20 sp|P23437|CDK2_XENLA Cyclin-dependent kinase 2 OS=Xenopus laevis ... 96.3 3e-20 sp|Q9SZ67|WRK19_ARATH Probable WRKY transcription factor 19 OS=Ar... 101 3e-20 sp|Q6GPK9|TAOK2_XENLA Serine/threonine-protein kinase TAO2 OS=Xen... 100 3e-20 sp|O61125|STK4_DICDI Serine/threonine-protein kinase 4 homolog A ... 99.0 3e-20 sp|P79749|PGFRB_TAKRU Platelet-derived growth factor receptor bet... 100 4e-20 sp|Q9Z2W1|STK25_MOUSE Serine/threonine-protein kinase 25 OS=Mus m... 98.2 4e-20 sp|Q5UQG7|YR818_MIMIV Putative serine/threonine-protein kinase/re... 101 4e-20 sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Hom... 100 4e-20 sp|O49839|PBL2_ARATH Probable serine/threonine-protein kinase PBL... 98.2 4e-20 sp|Q6QNF3|PGFRB_CANLF Platelet-derived growth factor receptor bet... 100 4e-20 sp|Q9XI96|PERK7_ARATH Proline-rich receptor-like protein kinase P... 100 4e-20 sp|P35916|VGFR3_HUMAN Vascular endothelial growth factor receptor... 100 4e-20 sp|Q9SY91|PBL15_ARATH Probable serine/threonine-protein kinase PB... 98.2 4e-20 sp|O43283|M3K13_HUMAN Mitogen-activated protein kinase kinase kin... 100 4e-20 sp|P28028|BRAF_MOUSE Serine/threonine-protein kinase B-raf OS=Mus... 100 4e-20 sp|Q04982|BRAF_CHICK Serine/threonine-protein kinase B-raf OS=Gal... 100 5e-20 sp|Q8T2I8|SEPA_DICDI Serine/threonine-protein kinase sepA OS=Dict... 100 5e-20 sp|P34908|BRAF_COTJA Serine/threonine-protein kinase B-raf OS=Cot... 100 5e-20 sp|Q9C6K9|LRL11_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 99.8 5e-20 sp|Q5R8X7|M3K13_PONAB Mitogen-activated protein kinase kinase kin... 100 5e-20 sp|C0LGQ7|Y4245_ARATH Probable LRR receptor-like serine/threonine... 100 5e-20 sp|Q9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 OS=Homo ... 98.2 5e-20 sp|Q80YP0|CDK3_MOUSE Cyclin-dependent kinase 3 OS=Mus musculus OX... 95.9 5e-20 sp|Q99N57|RAF1_MOUSE RAF proto-oncogene serine/threonine-protein ... 99.8 5e-20 sp|Q84M95|PBL28_ARATH Probable serine/threonine-protein kinase PB... 97.1 5e-20 sp|B0LT89|STK24_RAT Serine/threonine-protein kinase 24 OS=Rattus ... 97.8 5e-20 sp|Q3SWY6|STK25_BOVIN Serine/threonine-protein kinase 25 OS=Bos t... 97.8 5e-20 sp|Q99KH8|STK24_MOUSE Serine/threonine-protein kinase 24 OS=Mus m... 97.8 5e-20 sp|Q869X3|Y9851_DICDI Probable serine/threonine-protein kinase DD... 100 6e-20 sp|Q9XI87|VIK_ARATH Serine/threonine-protein kinase VIK OS=Arabid... 97.8 6e-20 sp|F1NBT0|STK10_CHICK Serine/threonine-protein kinase 10 OS=Gallu... 100 6e-20 sp|G5ED65|VER1_CAEEL Protein ver-1 OS=Caenorhabditis elegans OX=6... 100 6e-20 sp|Q9LDZ5|PBL21_ARATH Probable serine/threonine-protein kinase PB... 97.1 6e-20 sp|Q9SF86|PCRK1_ARATH Serine/threonine-protein kinase PCRK1 OS=Ar... 97.4 6e-20 sp|P09619|PGFRB_HUMAN Platelet-derived growth factor receptor bet... 100 7e-20 sp|Q55CA6|Y0146_DICDI Probable serine/threonine-protein kinase DD... 99.4 7e-20 sp|Q7ZYJ0|TAO1B_XENLA Serine/threonine-protein kinase TAO1-B OS=X... 100 7e-20 sp|Q55EC7|GEFX_DICDI RasGEF domain-containing serine/threonine-pr... 99.8 8e-20 sp|Q05030|PGFRB_RAT Platelet-derived growth factor receptor beta ... 99.8 8e-20 sp|Q91821|MELK_XENLA Maternal embryonic leucine zipper kinase OS=... 99.0 8e-20 sp|Q28GW8|MELK_XENTR Maternal embryonic leucine zipper kinase OS=... 99.0 9e-20 sp|P05622|PGFRB_MOUSE Platelet-derived growth factor receptor bet... 99.8 9e-20 sp|Q9SFT7|PBL26_ARATH Probable serine/threonine-protein kinase PB... 97.1 9e-20 sp|O61122|SVKA_DICDI Serine/threonine-protein kinase svkA OS=Dict... 97.8 9e-20 sp|F4HQ17|LRL14_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 99.0 9e-20 sp|Q9P289|STK26_HUMAN Serine/threonine-protein kinase 26 OS=Homo ... 97.1 1e-19 sp|Q9FPR3|EDR1_ARATH Serine/threonine-protein kinase EDR1 OS=Arab... 99.4 1e-19 sp|Q924U5|TESK2_RAT Dual specificity testis-specific protein kina... 98.2 1e-19 sp|Q55E58|PATS1_DICDI Probable serine/threonine-protein kinase pa... 100 1e-19 sp|Q99JT2|STK26_MOUSE Serine/threonine-protein kinase 26 OS=Mus m... 96.7 1e-19 sp|Q7T6X2|YR826_MIMIV Putative serine/threonine-protein kinase/re... 99.8 1e-19 sp|O00506|STK25_HUMAN Serine/threonine-protein kinase 25 OS=Homo ... 97.1 1e-19 sp|Q9ZUF4|RIPK_ARATH Serine/threonine-protein kinase RIPK OS=Arab... 97.1 1e-19 sp|P09560|RAF1_XENLA RAF proto-oncogene serine/threonine-protein ... 98.2 1e-19 sp|P18160|SPLA_DICDI Dual specificity protein kinase splA OS=Dict... 99.4 1e-19 sp|Q23915|KINX_DICDI Probable serine/threonine-protein kinase kin... 99.0 1e-19 sp|Q54VC0|Y9865_DICDI Probable serine/threonine-protein kinase DD... 96.3 2e-19 sp|Q8VCT9|TESK2_MOUSE Dual specificity testis-specific protein ki... 97.4 2e-19 sp|A8WYE4|PAR1_CAEBR Serine/threonine-protein kinase par-1 OS=Cae... 98.6 2e-19 sp|P53670|LIMK2_RAT LIM domain kinase 2 OS=Rattus norvegicus OX=1... 97.8 2e-19 sp|Q9TW45|PAR1_CAEEL Serine/threonine-protein kinase par-1 OS=Cae... 98.6 2e-19 sp|B4MR28|PTK7_DROWI Tyrosine-protein kinase-like otk OS=Drosophi... 98.6 2e-19 sp|Q86AT8|SPKA_DICDI Stress-activated protein kinase alpha OS=Dic... 97.8 2e-19 sp|O54785|LIMK2_MOUSE LIM domain kinase 2 OS=Mus musculus OX=1009... 97.4 3e-19 sp|P32562|CDC5_YEAST Cell cycle serine/threonine-protein kinase C... 97.4 3e-19 sp|Q9I9E0|TAOK3_CHICK Serine/threonine-protein kinase TAO3 OS=Gal... 97.8 3e-19 sp|Q55EI8|Y9956_DICDI Probable serine/threonine-protein kinase DD... 98.2 3e-19 sp|Q0WRY5|PBL7_ARATH Probable serine/threonine-protein kinase PBL... 94.7 3e-19 sp|Q14680|MELK_HUMAN Maternal embryonic leucine zipper kinase OS=... 97.4 3e-19 sp|Q27324|RYK1_DROME Tyrosine-protein kinase Drl OS=Drosophila me... 97.1 3e-19 sp|Q86HG9|Y9871_DICDI Probable serine/threonine-protein kinase DD... 97.8 3e-19 sp|Q8RWW0|ALE2_ARATH Receptor-like serine/threonine-protein kinas... 97.4 3e-19 sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapiens OX=9606... 97.1 4e-19 sp|Q9ZNQ8|PERK4_ARATH Proline-rich receptor-like protein kinase P... 96.7 4e-19 sp|Q9CAL8|PEK13_ARATH Proline-rich receptor-like protein kinase P... 97.1 4e-19 sp|F1QGZ6|MELK_DANRE Maternal embryonic leucine zipper kinase OS=... 96.7 4e-19 sp|Q10407|MKH1_SCHPO MAP kinase kinase kinase mkh1 OS=Schizosacch... 97.4 4e-19 sp|Q6DD27|TAOK3_XENLA Serine/threonine-protein kinase TAO3 OS=Xen... 97.4 4e-19 sp|Q8H186|PBL1_ARATH Probable serine/threonine-protein kinase PBL... 94.4 4e-19 sp|A9RVK2|M3K1B_PHYPA Mitogen-activated protein kinase kinase kin... 97.1 5e-19 sp|Q32L23|LIMK2_BOVIN LIM domain kinase 2 OS=Bos taurus OX=9913 G... 96.7 5e-19 sp|A6ZU08|TOS3_YEAS7 Serine/threonine-protein kinase TOS3 OS=Sacc... 95.9 5e-19 sp|C0LGD7|Y1684_ARATH Probable LRR receptor-like serine/threonine... 97.1 5e-19 sp|P43637|TOS3_YEAST Serine/threonine-protein kinase TOS3 OS=Sacc... 95.9 6e-19 sp|Q6NU21|TAO1A_XENLA Serine/threonine-protein kinase TAO1-A OS=X... 97.1 6e-19 sp|Q9LZF8|PCRK2_ARATH Serine/threonine-protein kinase PCRK2 OS=Ar... 94.7 6e-19 sp|P52497|SNF1_CANAX Carbon catabolite-derepressing protein kinas... 96.3 6e-19 sp|Q3TYD6|LMTK2_MOUSE Serine/threonine-protein kinase LMTK2 OS=Mu... 97.1 6e-19 sp|F4IS56|ILK1_ARATH Integrin-linked protein kinase 1 OS=Arabidop... 95.1 6e-19 sp|Q5R4F3|TAOK3_PONAB Serine/threonine-protein kinase TAO3 OS=Pon... 96.7 6e-19 sp|Q9M0T3|MP3K3_ARATH Mitogen-activated protein kinase kinase kin... 95.9 6e-19 sp|Q54DF2|MRKA_DICDI Probable serine/threonine-protein kinase MAR... 97.1 7e-19 sp|P08458|SPS1_YEAST Sporulation-specific protein 1 OS=Saccharomy... 95.1 7e-19 sp|P43298|TMK1_ARATH Receptor protein kinase TMK1 OS=Arabidopsis ... 96.7 7e-19 sp|Q0IHQ8|STK10_XENTR Serine/threonine-protein kinase 10 OS=Xenop... 96.7 7e-19 sp|Q8R4K2|IRAK4_MOUSE Interleukin-1 receptor-associated kinase 4 ... 94.7 7e-19 sp|H2KZW3|M3K20_CAEEL Mitogen-activated protein kinase kinase kin... 96.3 7e-19 sp|Q8GX23|PERK5_ARATH Proline-rich receptor-like protein kinase P... 95.9 8e-19 sp|P53666|LIMK2_CHICK LIM domain kinase 2 OS=Gallus gallus OX=903... 95.9 8e-19 sp|P53668|LIMK1_MOUSE LIM domain kinase 1 OS=Mus musculus OX=1009... 95.9 8e-19 sp|A4K2M3|STK4_PAPAN Serine/threonine-protein kinase 4 OS=Papio a... 94.7 9e-19 sp|Q54R58|YTYK2_DICDI Probable tyrosine-protein kinase DDB_G02833... 95.9 1e-18 sp|Q9LRY1|PBL25_ARATH Probable serine/threonine-protein kinase PB... 93.2 1e-18 sp|G4NEB8|MST7_PYRO7 Mitogen-activated protein kinase kinae MST7 ... 93.6 1e-18 sp|A4K2W5|STK4_AOTNA Serine/threonine-protein kinase 4 OS=Aotus n... 94.4 1e-18 sp|Q86I06|NEK3_DICDI Probable serine/threonine-protein kinase nek... 96.3 1e-18 sp|A0A2R6XIK6|PRAF_MARPO RAF-like serine/threonine-protein kinase... 96.3 1e-18 sp|Q9H2K8|TAOK3_HUMAN Serine/threonine-protein kinase TAO3 OS=Hom... 95.9 1e-18 sp|Q54H46|DRKA_DICDI Probable serine/threonine-protein kinase drk... 95.1 1e-18 sp|Q9FE20|PBS1_ARATH Serine/threonine-protein kinase PBS1 OS=Arab... 94.0 1e-18 sp|Q1PDV6|PBL27_ARATH Serine/threonine-protein kinase PBL27 OS=Ar... 94.4 1e-18 sp|Q9JI11|STK4_MOUSE Serine/threonine-protein kinase 4 OS=Mus mus... 94.4 1e-18 sp|Q9P0L2|MARK1_HUMAN Serine/threonine-protein kinase MARK1 OS=Ho... 95.5 1e-18 sp|P38692|KIC1_YEAST Serine/threonine-protein kinase KIC1 OS=Sacc... 95.9 1e-18 sp|A8X775|DLK1_CAEBR Mitogen-activated protein kinase kinase kina... 95.5 1e-18 sp|Q13043|STK4_HUMAN Serine/threonine-protein kinase 4 OS=Homo sa... 94.4 1e-18 sp|Q96S53|TESK2_HUMAN Dual specificity testis-specific protein ki... 94.7 1e-18 sp|A4K2T0|STK4_MACMU Serine/threonine-protein kinase 4 OS=Macaca ... 94.4 1e-18 sp|A4K2Y1|STK4_CHLAE Serine/threonine-protein kinase 4 OS=Chloroc... 94.0 1e-18 sp|P53669|LIMK1_RAT LIM domain kinase 1 OS=Rattus norvegicus OX=1... 95.1 1e-18 sp|Q80YE4|LMTK1_MOUSE Serine/threonine-protein kinase LMTK1 OS=Mu... 95.9 1e-18 sp|Q01389|BCK1_YEAST Serine/threonine-protein kinase BCK1/SLK1/SS... 95.9 1e-18 sp|P0DP15|SNF1_FUSVI Sucrose non-fermenting protein kinase 1 OS=F... 95.1 1e-18 sp|Q54IP4|SHKB_DICDI Dual specificity protein kinase shkB OS=Dict... 95.1 1e-18 sp|Q55CE0|MKCF_DICDI Probable serine/threonine-protein kinase mkc... 95.1 1e-18 sp|A4K2Q5|STK4_OTOGA Serine/threonine-protein kinase 4 OS=Otolemu... 94.0 2e-18 sp|Q5E9L6|STK4_BOVIN Serine/threonine-protein kinase 4 OS=Bos tau... 94.0 2e-18 sp|A4K2S1|STK4_LEMCA Serine/threonine-protein kinase 4 OS=Lemur c... 94.0 2e-18 sp|Q96L34|MARK4_HUMAN MAP/microtubule affinity-regulating kinase ... 95.1 2e-18 sp|Q9FIL7|CRCK1_ARATH Calmodulin-binding receptor-like cytoplasmi... 93.6 2e-18 sp|Q9V3Q6|M3K7_DROME Mitogen-activated protein kinase kinase kina... 95.1 2e-18 sp|D3ZGQ5|NEK8_RAT Serine/threonine-protein kinase Nek8 OS=Rattus... 95.1 2e-18 sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens OX=9606... 94.7 2e-18 sp|Q8CIP4|MARK4_MOUSE MAP/microtubule affinity-regulating kinase ... 95.1 2e-18 sp|Q86SG6|NEK8_HUMAN Serine/threonine-protein kinase Nek8 OS=Homo... 94.7 2e-18 sp|Q5E9Y0|CDK2_BOVIN Cyclin-dependent kinase 2 OS=Bos taurus OX=9... 90.9 2e-18 sp|A4K2P5|STK4_COLGU Serine/threonine-protein kinase 4 OS=Colobus... 94.0 2e-18 sp|P46573|PBL10_ARATH Probable serine/threonine-protein kinase PB... 92.8 2e-18 sp|Q9FX43|M2K9_ARATH Mitogen-activated protein kinase kinase 9 OS... 91.3 2e-18 sp|Q54QQ1|PHG2_DICDI Serine/threonine-protein kinase phg2 OS=Dict... 95.5 2e-18 sp|Q7SY52|STK10_DANRE Serine/threonine-protein kinase 10 OS=Danio... 95.1 2e-18 sp|P46549|SULU_CAEEL Serine/threonine-protein kinase SULU OS=Caen... 95.1 2e-18 sp|P0C5E2|LRL12_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 94.4 2e-18 sp|Q9SAJ2|RAF20_ARATH RAF-like serine/threonine-protein kinase 20... 95.1 2e-18 sp|Q6ZMQ8|LMTK1_HUMAN Serine/threonine-protein kinase LMTK1 OS=Ho... 95.1 2e-18 sp|Q9SIT1|TMK3_ARATH Receptor-like kinase TMK3 OS=Arabidopsis tha... 95.1 2e-18 sp|O08679|MARK2_RAT Serine/threonine-protein kinase MARK2 OS=Ratt... 94.4 3e-18 sp|Q9LK43|TMK4_ARATH Receptor-like kinase TMK4 OS=Arabidopsis tha... 94.7 3e-18 sp|O64768|RAF24_ARATH RAF-like serine/threonine-protein kinase 24... 95.1 3e-18 sp|Q54WS5|ROCO6_DICDI Probable serine/threonine-protein kinase ro... 95.1 3e-18 sp|Q9V422|RYK2_DROME Tyrosine-protein kinase Dnt OS=Drosophila me... 94.0 3e-18 sp|Q32MK0|MYLK3_HUMAN Myosin light chain kinase 3 OS=Homo sapiens... 94.4 3e-18 sp|Q6Z8C8|CDKF4_ORYSJ Cyclin-dependent kinase F-4 OS=Oryza sativa... 92.8 3e-18 sp|Q7L7X3|TAOK1_HUMAN Serine/threonine-protein kinase TAO1 OS=Hom... 94.7 3e-18 sp|Q00526|CDK3_HUMAN Cyclin-dependent kinase 3 OS=Homo sapiens OX... 90.5 3e-18 sp|Q8BYC6|TAOK3_MOUSE Serine/threonine-protein kinase TAO3 OS=Mus... 94.7 3e-18 sp|Q802A6|STK4_SQUAC Serine/threonine-protein kinase 3/4 OS=Squal... 93.2 3e-18 sp|Q91ZR4|NEK8_MOUSE Serine/threonine-protein kinase Nek8 OS=Mus ... 94.0 3e-18 sp|B7ZR30|STK10_XENLA Serine/threonine-protein kinase 10-A OS=Xen... 94.4 3e-18 sp|P24941|CDK2_HUMAN Cyclin-dependent kinase 2 OS=Homo sapiens OX... 90.1 3e-18 sp|Q03141|MARK3_MOUSE MAP/microtubule affinity-regulating kinase ... 94.4 3e-18 sp|Q95KV0|IKKB_BOVIN Inhibitor of nuclear factor kappa-B kinase s... 94.4 3e-18 sp|Q9HFW2|CLA4_EREGS Serine/threonine-protein kinase CLA4 OS=Erem... 94.4 3e-18 sp|O88664|TAOK1_RAT Serine/threonine-protein kinase TAO1 OS=Rattu... 94.4 3e-18 sp|Q38997|KIN10_ARATH SNF1-related protein kinase catalytic subun... 93.2 3e-18 sp|Q5F2E8|TAOK1_MOUSE Serine/threonine-protein kinase TAO1 OS=Mus... 94.4 3e-18 sp|Q5RDG7|MYLK3_PONAB Myosin light chain kinase 3 OS=Pongo abelii... 94.4 3e-18 sp|Q9FLJ8|Y5613_ARATH Probable receptor-like protein kinase At5g6... 94.4 3e-18 sp|Q94CG0|CIPKL_ARATH CBL-interacting serine/threonine-protein ki... 92.0 4e-18 sp|O88351|IKKB_MOUSE Inhibitor of nuclear factor kappa-B kinase s... 94.0 4e-18 sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Ho... 94.0 4e-18 sp|Q6NKZ9|Y4345_ARATH Probable receptor-like serine/threonine-pro... 92.4 4e-18 sp|P0C0K7|EPHB6_RAT Ephrin type-B receptor 6 OS=Rattus norvegicus... 94.4 4e-18 sp|Q3E8W4|ANX2_ARATH Receptor-like protein kinase ANXUR2 OS=Arabi... 94.0 4e-18 sp|Q1PE89|PBL24_ARATH Probable serine/threonine-protein kinase PB... 91.7 4e-18 sp|B4KPU0|PTK7_DROMO Tyrosine-protein kinase-like otk OS=Drosophi... 94.4 4e-18 sp|Q05609|CTR1_ARATH Serine/threonine-protein kinase CTR1 OS=Arab... 94.0 4e-18 sp|C0LGE0|Y1765_ARATH Probable LRR receptor-like serine/threonine... 94.4 4e-18 sp|Q9LW83|CE101_ARATH G-type lectin S-receptor-like serine/threon... 94.0 4e-18 sp|Q852Q2|OSK1_ORYSJ Serine/threonine protein kinase OSK1 OS=Oryz... 92.8 4e-18 sp|Q94C95|ATG1A_ARATH Serine/threonine-protein kinase ATG1a OS=Ar... 93.2 5e-18 sp|Q53UA7|TAOK3_RAT Serine/threonine-protein kinase TAO3 OS=Rattu... 94.0 5e-18 sp|O42565|LIMK1_XENLA LIM domain kinase 1 OS=Xenopus laevis OX=83... 93.2 5e-18 sp|Q9NGW9|MKCB_DICDI Probable serine/threonine-protein kinase mkc... 93.6 5e-18 sp|Q04759|KPCT_HUMAN Protein kinase C theta type OS=Homo sapiens ... 93.6 5e-18 sp|A8C984|MYLK3_DANRE Myosin light chain kinase 3 OS=Danio rerio ... 93.6 5e-18 sp|Q8VHF0|MARK3_RAT MAP/microtubule affinity-regulating kinase 3 ... 93.6 5e-18 sp|Q9ZUE0|PEK12_ARATH Proline-rich receptor-like protein kinase P... 93.6 5e-18 sp|O81906|B120_ARATH G-type lectin S-receptor-like serine/threoni... 93.6 5e-18 sp|P92958|KIN11_ARATH SNF1-related protein kinase catalytic subun... 92.4 5e-18 sp|Q9FID9|Y5389_ARATH Probable receptor-like protein kinase At5g3... 93.6 6e-18 sp|Q05512|MARK2_MOUSE Serine/threonine-protein kinase MARK2 OS=Mu... 93.6 6e-18 sp|B3MH43|PTK7_DROAN Tyrosine-protein kinase-like otk OS=Drosophi... 94.0 6e-18 sp|O49545|BAME1_ARATH Leucine-rich repeat receptor-like serine/th... 93.6 6e-18 sp|Q6J9G0|STYK1_HUMAN Tyrosine-protein kinase STYK1 OS=Homo sapie... 91.3 6e-18 sp|E9PT87|MYLK3_RAT Myosin light chain kinase 3 OS=Rattus norvegi... 93.2 6e-18 sp|Q93YN1|CRPK1_ARATH Cold-responsive protein kinase 1 OS=Arabido... 90.9 7e-18 sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase ... 93.2 7e-18 sp|O14920|IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase s... 93.2 7e-18 sp|Q9FLZ3|KIN12_ARATH SNF1-related protein kinase catalytic subun... 92.0 7e-18 sp|Q9LV48|PERK1_ARATH Proline-rich receptor-like protein kinase P... 92.8 7e-18 sp|O74456|PEF1_SCHPO Serine/threonine-protein kinase pef1 OS=Schi... 89.0 7e-18 sp|Q54XJ4|Y8901_DICDI Probable serine/threonine-protein kinase DD... 93.6 8e-18 sp|O55076|CDK2_CRIGR Cyclin-dependent kinase 2 OS=Cricetulus gris... 89.0 8e-18 sp|Q6P3Q4|STK4_XENTR Serine/threonine-protein kinase 4 OS=Xenopus... 91.7 8e-18 sp|Q8MVR1|GBPC_DICDI Cyclic GMP-binding protein C OS=Dictyosteliu... 93.6 8e-18 sp|Q3UIZ8|MYLK3_MOUSE Myosin light chain kinase 3 OS=Mus musculus... 92.8 8e-18 sp|A8XJW8|CST1_CAEBR Serine/threonine-protein kinase cst-1 OS=Cae... 91.7 8e-18 sp|P50527|STE20_SCHPO Serine/threonine-protein kinase shk1/pak1 O... 92.4 9e-18 sp|P14056|ARAF_RAT Serine/threonine-protein kinase A-Raf OS=Rattu... 92.4 9e-18 sp|O08678|MARK1_RAT Serine/threonine-protein kinase MARK1 OS=Ratt... 92.8 9e-18 sp|O01700|DLK1_CAEEL Mitogen-activated protein kinase kinase kina... 93.2 9e-18 sp|Q54JQ1|MKCC_DICDI Probable serine/threonine-protein kinase mkc... 93.2 9e-18 sp|Q8VHJ5|MARK1_MOUSE Serine/threonine-protein kinase MARK1 OS=Mu... 92.8 9e-18 sp|P04627|ARAF_MOUSE Serine/threonine-protein kinase A-Raf OS=Mus... 92.4 9e-18 sp|Q6PA14|STK4_XENLA Serine/threonine-protein kinase 4 OS=Xenopus... 91.7 9e-18 sp|Q9LT96|Y5977_ARATH Probable leucine-rich repeat receptor-like ... 93.2 9e-18 sp|Q9ASQ6|Y1972_ARATH Probable LRR receptor-like serine/threonine... 93.2 1e-17 sp|Q9LX66|HERK_ARATH Receptor-like protein kinase HERK 1 OS=Arabi... 92.8 1e-17 sp|P43450|CDK2_CARAU Cyclin-dependent kinase 2 OS=Carassius aurat... 89.0 1e-17 sp|P51954|NEK1_MOUSE Serine/threonine-protein kinase Nek1 OS=Mus ... 93.2 1e-17 sp|B4HNW4|PTK7_DROSE Tyrosine-protein kinase-like otk OS=Drosophi... 92.8 1e-17 sp|O70146|TESK1_MOUSE Dual specificity testis-specific protein ki... 92.0 1e-17 sp|Q9QY78|IKKB_RAT Inhibitor of nuclear factor kappa-B kinase sub... 92.4 1e-17 sp|Q60855|RIPK1_MOUSE Receptor-interacting serine/threonine-prote... 92.0 1e-17 sp|Q9NB31|CST1_CAEEL Serine/threonine-protein kinase cst-1 OS=Cae... 91.3 1e-17 sp|Q63572|TESK1_RAT Dual specificity testis-specific protein kina... 92.0 1e-17 sp|Q2QAV0|TIO_ARATH Serine/threonine-protein kinase TIO OS=Arabid... 92.8 1e-17 sp|P17157|PHO85_YEAST Cyclin-dependent protein kinase PHO85 OS=Sa... 88.6 1e-17 sp|Q69ZA1|CDK13_MOUSE Cyclin-dependent kinase 13 OS=Mus musculus ... 92.8 1e-17 sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo ... 92.4 1e-17 sp|E1BB52|CDK13_BOVIN Cyclin-dependent kinase 13 OS=Bos taurus OX... 92.8 1e-17 sp|Q9FN92|Y5597_ARATH Probable receptor-like protein kinase At5g5... 92.4 1e-17 sp|Q14004|CDK13_HUMAN Cyclin-dependent kinase 13 OS=Homo sapiens ... 92.8 1e-17 sp|Q6AWJ9|PTK7_DROME Tyrosine-protein kinase-like otk OS=Drosophi... 92.4 1e-17 sp|Q6J9G1|STYK1_MOUSE Tyrosine-protein kinase STYK1 OS=Mus muscul... 90.5 1e-17 sp|O65530|PEK14_ARATH Proline-rich receptor-like protein kinase P... 92.0 1e-17 sp|B4QC63|PTK7_DROSI Tyrosine-protein kinase-like otk OS=Drosophi... 92.4 1e-17 sp|Q9FID8|Y5900_ARATH Putative receptor-like protein kinase At5g3... 92.4 2e-17 sp|Q0KHQ5|TAO_DROME Serine/threonine-protein kinase Tao OS=Drosop... 92.4 2e-17 sp|P48963|CDK2_MESAU Cyclin-dependent kinase 2 OS=Mesocricetus au... 88.2 2e-17 sp|O19004|ARAF_PIG Serine/threonine-protein kinase A-Raf OS=Sus s... 91.7 2e-17 sp|Q9C660|PEK10_ARATH Proline-rich receptor-like protein kinase P... 92.0 2e-17 sp|Q5ZJK4|STK4_CHICK Serine/threonine-protein kinase 4 OS=Gallus ... 90.9 2e-17 sp|Q8QFP8|LIMK1_CHICK LIM domain kinase 1 OS=Gallus gallus OX=903... 91.7 2e-17 sp|P52304|POLO_DROME Serine/threonine-protein kinase polo OS=Dros... 91.3 2e-17 sp|Q8BTW9|PAK4_MOUSE Serine/threonine-protein kinase PAK 4 OS=Mus... 91.3 2e-17 sp|P51956|NEK3_HUMAN Serine/threonine-protein kinase Nek3 OS=Homo... 90.9 2e-17 sp|Q63699|CDK2_RAT Cyclin-dependent kinase 2 OS=Rattus norvegicus... 88.2 2e-17 sp|B4P5Q9|PTK7_DROYA Tyrosine-protein kinase-like otk OS=Drosophi... 92.0 2e-17 sp|Q54RV3|PAKG_DICDI Serine/threonine-protein kinase pakG OS=Dict... 92.0 2e-17 sp|Q86YV6|MYLK4_HUMAN Myosin light chain kinase family member 4 O... 89.4 2e-17 sp|Q2RA93|WNK6_ORYSJ Probable serine/threonine-protein kinase WNK... 90.1 2e-17 sp|Q8IVT5|KSR1_HUMAN Kinase suppressor of Ras 1 OS=Homo sapiens O... 92.0 2e-17 sp|Q6FKD4|PHO85_CANGA Negative regulator of the PHO system OS=Can... 87.8 2e-17 sp|Q61G93|ROL3_CAEBR Protein roller-3 OS=Caenorhabditis briggsae ... 92.4 2e-17 sp|Q9VXE5|PAKM_DROME Serine/threonine-protein kinase PAK mbt OS=D... 91.3 2e-17 sp|Q1ZXD6|ROCO5_DICDI Probable serine/threonine-protein kinase ro... 92.4 2e-17 sp|Q9N2L7|PLK2_CAEEL Serine/threonine-protein kinase plk-2 OS=Cae... 91.3 2e-17 sp|Q41328|PTI1_SOLLC Pto-interacting protein 1 OS=Solanum lycoper... 88.6 2e-17 sp|Q86IX1|DST1_DICDI Serine/threonine-protein kinase dst1 OS=Dict... 91.3 2e-17 sp|Q9LS95|PERK6_ARATH Putative proline-rich receptor-like protein... 91.3 2e-17 sp|Q9SGY7|PEK11_ARATH Putative proline-rich receptor-like protein... 91.3 2e-17 sp|Q55D99|PAKA_DICDI Serine/threonine-protein kinase pakA OS=Dict... 91.7 3e-17 sp|P06782|SNF1_YEAST Carbon catabolite-derepressing protein kinas... 90.9 3e-17 sp|O94168|SNF1_CANTR Carbon catabolite-derepressing protein kinas... 90.9 3e-17 sp|B5DE93|CDK12_XENTR Cyclin-dependent kinase 12 OS=Xenopus tropi... 91.7 3e-17 sp|Q9LSL5|LRK92_ARATH L-type lectin-domain containing receptor ki... 91.3 3e-17 sp|Q9GN62|PAR4_CAEEL Serine/threonine-protein kinase par-4 OS=Cae... 90.9 3e-17 sp|E1BK52|STK10_BOVIN Serine/threonine-protein kinase 10 OS=Bos t... 91.7 3e-17 sp|Q28DZ1|IKKA_XENTR Inhibitor of nuclear factor kappa-B kinase s... 91.3 3e-17 sp|Q9CAH1|Y1725_ARATH Putative receptor-like protein kinase At1g7... 89.7 3e-17 sp|Q02111|KPCT_MOUSE Protein kinase C theta type OS=Mus musculus ... 90.9 3e-17 sp|B3NS99|PTK7_DROER Tyrosine-protein kinase-like otk OS=Drosophi... 91.3 3e-17 sp|Q9M2S4|LRKS4_ARATH L-type lectin-domain containing receptor ki... 90.9 3e-17 sp|Q9H4B4|PLK3_HUMAN Serine/threonine-protein kinase PLK3 OS=Homo... 90.5 3e-17 sp|Q54TH6|Y9863_DICDI Probable serine/threonine-protein kinase DD... 90.5 3e-17 sp|Q00372|SNF1_CANGA Carbon catabolite-derepressing protein kinas... 90.5 4e-17 sp|Q556S2|PAKH_DICDI Serine/threonine-protein kinase pakH OS=Dict... 90.1 4e-17 sp|Q869N2|PAKB_DICDI Serine/threonine-protein kinase pakB OS=Dict... 90.9 4e-17 sp|Q92918|M4K1_HUMAN Mitogen-activated protein kinase kinase kina... 90.9 4e-17 sp|Q9SR05|ANX1_ARATH Receptor-like protein kinase ANXUR1 OS=Arabi... 90.9 4e-17 sp|Q1PEM5|PERK3_ARATH Proline-rich receptor-like protein kinase P... 89.7 4e-17 sp|Q9ZT07|RKS1_ARATH G-type lectin S-receptor-like serine/threoni... 90.9 4e-17 sp|P53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 OS=Homo... 90.1 4e-17 sp|Q54U31|SHKD_DICDI Dual specificity protein kinase shkD OS=Dict... 90.5 4e-17 sp|Q9VI13|PAK_DROME Serine/threonine-protein kinase Pak OS=Drosop... 90.5 4e-17 sp|Q9SFX0|PBL22_ARATH Probable serine/threonine-protein kinase PB... 88.2 5e-17 sp|Q96PY6|NEK1_HUMAN Serine/threonine-protein kinase Nek1 OS=Homo... 90.9 5e-17 sp|P97377|CDK2_MOUSE Cyclin-dependent kinase 2 OS=Mus musculus OX... 87.8 5e-17 sp|B4GBH0|PTK7_DROPE Tyrosine-protein kinase-like otk OS=Drosophi... 90.9 5e-17 sp|F4JZW1|PBL13_ARATH Serine/threonine-protein kinase PBL13 OS=Ar... 89.4 5e-17 sp|G5EFU0|PK2_CAEEL Serine/threonine-protein kinase pak-2 OS=Caen... 89.4 5e-17 sp|Q9M2Z1|BAME2_ARATH Leucine-rich repeat receptor-like serine/th... 90.5 5e-17 sp|O14299|WIS4_SCHPO MAP kinase kinase kinase wis4 OS=Schizosacch... 90.9 5e-17 sp|Q7ZZC8|NEK9_XENLA Serine/threonine-protein kinase Nek9 OS=Xeno... 90.5 5e-17 sp|E9PTG8|STK10_RAT Serine/threonine-protein kinase 10 OS=Rattus ... 90.5 6e-17 sp|Q9FN94|RLK0_ARATH Receptor-like protein kinase At5g59670 OS=Ar... 90.5 6e-17 sp|O55098|STK10_MOUSE Serine/threonine-protein kinase 10 OS=Mus m... 90.5 6e-17 sp|Q290N5|PTK7_DROPS Tyrosine-protein kinase-like otk OS=Drosophi... 90.5 6e-17 sp|Q1RMT8|IRAK4_BOVIN Interleukin-1 receptor-associated kinase 4 ... 89.0 6e-17 sp|Q14AX6|CDK12_MOUSE Cyclin-dependent kinase 12 OS=Mus musculus ... 90.9 6e-17 sp|Q9T020|Y4391_ARATH Probable receptor-like protein kinase At4g3... 90.5 6e-17 sp|Q61097|KSR1_MOUSE Kinase suppressor of Ras 1 OS=Mus musculus O... 90.1 6e-17 sp|Q15569|TESK1_HUMAN Dual specificity testis-specific protein ki... 89.7 6e-17 sp|Q9M8S2|LIPG2_ARATH Receptor-like kinase LIP2 OS=Arabidopsis th... 89.4 7e-17 sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Hom... 89.4 7e-17 sp|Q9WTQ0|KPCT_RAT Protein kinase C theta type OS=Rattus norvegic... 89.7 7e-17 sp|A8WZ92|SPE8_CAEBR Spermatocyte protein spe-8 OS=Caenorhabditis... 89.0 7e-17 sp|Q3MJK5|CDK12_RAT Cyclin-dependent kinase 12 OS=Rattus norvegic... 90.5 7e-17 sp|Q552C1|Y9957_DICDI Probable serine/threonine-protein kinase DD... 90.5 7e-17 sp|Q6CWQ4|IPL1_KLULA Spindle assembly checkpoint kinase OS=Kluyve... 87.4 7e-17 sp|P10398|ARAF_HUMAN Serine/threonine-protein kinase A-Raf OS=Hom... 89.4 7e-17 sp|O22833|LRK54_ARATH L-type lectin-domain containing receptor ki... 89.7 7e-17 sp|Q9R012|PLK2_RAT Serine/threonine-protein kinase PLK2 OS=Rattus... 89.7 8e-17 sp|B5X564|CDC2C_ARATH Cyclin-dependent kinase C-2 C OS=Arabidopsi... 89.4 8e-17 sp|Q9FFW5|PERK8_ARATH Proline-rich receptor-like protein kinase P... 89.4 8e-17 sp|P53351|PLK2_MOUSE Serine/threonine-protein kinase PLK2 OS=Mus ... 89.4 9e-17 sp|Q2TA25|PLK1_BOVIN Serine/threonine-protein kinase PLK1 OS=Bos ... 89.4 9e-17 sp|Q9HGY5|PHO85_CANAX Negative regulator of the PHO system OS=Can... 86.3 1e-16 sp|Q9NYV4|CDK12_HUMAN Cyclin-dependent kinase 12 OS=Homo sapiens ... 90.1 1e-16 sp|Q5R4L1|PLK2_PONAB Serine/threonine-protein kinase PLK2 OS=Pong... 89.4 1e-16 sp|Q8RWC9|CIPK1_ARATH CBL-interacting serine/threonine-protein ki... 87.8 1e-16 sp|Q9Z1J2|NEK4_MOUSE Serine/threonine-protein kinase Nek4 OS=Mus ... 89.4 1e-16 sp|Q5QNM6|CIPKD_ORYSJ Putative CBL-interacting protein kinase 13 ... 88.6 1e-16 sp|Q9M0X5|CRK25_ARATH Cysteine-rich receptor-like protein kinase ... 89.4 1e-16 sp|Q86AE1|Y9853_DICDI Probable serine/threonine-protein kinase DD... 88.6 1e-16 sp|Q54L00|LIMKA_DICDI Probable LIM domain-containing serine/threo... 89.0 1e-16 sp|Q9NYY3|PLK2_HUMAN Serine/threonine-protein kinase PLK2 OS=Homo... 89.0 1e-16 sp|Q86HN7|PLK_DICDI Probable serine/threonine-protein kinase PLK ... 89.4 1e-16 sp|D2H526|CDK12_AILME Cyclin-dependent kinase 12 OS=Ailuropoda me... 89.7 1e-16 sp|Q9SJT0|Y2214_ARATH Probable receptor-like protein kinase At2g2... 89.4 1e-16 sp|O64793|Y1675_ARATH G-type lectin S-receptor-like serine/threon... 89.4 1e-16 sp|Q5ZJB4|IKKA_CHICK Inhibitor of nuclear factor kappa-B kinase s... 89.0 1e-16 sp|Q2ULU3|STE20_ASPOR Serine/threonine-protein kinase ste20 OS=As... 89.0 1e-16 sp|Q8GZ99|HPCA1_ARATH Leucine-rich repeat receptor protein kinase... 89.0 1e-16 sp|E1BB50|CDK12_BOVIN Cyclin-dependent kinase 12 OS=Bos taurus OX... 89.4 1e-16 sp|Q6BRY2|PHO85_DEBHA Negative regulator of the PHO system OS=Deb... 85.9 2e-16 sp|Q05006|CDC22_MEDSA Cell division control protein 2 homolog 2 O... 85.1 2e-16 sp|P34331|PLK1_CAEEL Serine/threonine-protein kinase plk-1 OS=Cae... 88.6 2e-16 sp|Q9R0A5|NEK3_MOUSE Serine/threonine-protein kinase Nek3 OS=Mus ... 87.8 2e-16 sp|O54748|STK3_RAT Serine/threonine-protein kinase 3 OS=Rattus no... 87.8 2e-16 sp|Q4G3H4|IKKA_DANRE Inhibitor of nuclear factor kappa-B kinase s... 88.6 2e-16 sp|Q6GM53|IKKA_XENLA Inhibitor of nuclear factor kappa-B kinase s... 88.6 2e-16 sp|Q54QI2|Y9877_DICDI Serine/threonine-protein kinase DDB_G028382... 89.0 2e-16 sp|Q9STK6|WNK3_ARATH Probable serine/threonine-protein kinase WNK... 87.8 2e-16 sp|Q852Q1|OSK4_ORYSJ Serine/threonine protein kinase OSK4 OS=Oryz... 87.8 2e-16 sp|B8BBT7|OSK4_ORYSI Serine/threonine protein kinase OSK4 OS=Oryz... 87.8 2e-16 sp|Q76P07|Y7165_DICDI Probable serine/threonine-protein kinase DD... 88.6 2e-16 sp|Q9SX31|PERK9_ARATH Proline-rich receptor-like protein kinase P... 88.6 2e-16 sp|Q07292|KRAF1_CAEEL Raf homolog serine/threonine-protein kinase... 88.6 2e-16 sp|Q9GRT1|MKK4_LEIME Putative mitogen-activated protein kinase ki... 85.9 2e-16 sp|Q9LQQ8|PBL5_ARATH Probable serine/threonine-protein kinase PBL... 87.0 2e-16 sp|Q9LK03|PERK2_ARATH Proline-rich receptor-like protein kinase P... 88.6 2e-16 sp|Q852Q0|OSK3_ORYSJ Serine/threonine protein kinase OSK3 OS=Oryz... 87.8 2e-16 sp|A2XFF4|OSK3_ORYSI Serine/threonine protein kinase OSK3 OS=Oryz... 87.8 2e-16 sp|Q62673|PLK1_RAT Serine/threonine-protein kinase PLK1 OS=Rattus... 88.2 2e-16 sp|Q8VZJ9|CRCK2_ARATH Calmodulin-binding receptor-like cytoplasmi... 86.7 2e-16 sp|Q9C821|PEK15_ARATH Proline-rich receptor-like protein kinase P... 87.8 2e-16 sp|Q9JI10|STK3_MOUSE Serine/threonine-protein kinase 3 OS=Mus mus... 87.4 2e-16 sp|P51957|NEK4_HUMAN Serine/threonine-protein kinase Nek4 OS=Homo... 88.6 2e-16 sp|Q5R7G9|NUAK2_PONAB NUAK family SNF1-like kinase 2 OS=Pongo abe... 88.2 2e-16 sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo sapi... 88.2 2e-16 sp|F4JBP3|ATG1B_ARATH Serine/threonine-protein kinase ATG1b OS=Ar... 88.2 2e-16 sp|O22808|LYK5_ARATH Protein LYK5 OS=Arabidopsis thaliana OX=3702... 88.2 2e-16 sp|Q9SZD5|LRK59_ARATH L-type lectin-domain containing receptor ki... 88.2 2e-16 sp|Q54MY9|MKCA_DICDI Probable serine/threonine-protein kinase mkc... 88.6 2e-16 sp|Q6IP06|STK3_XENLA Serine/threonine-protein kinase 3 OS=Xenopus... 87.4 2e-16 sp|Q9SCZ4|FERON_ARATH Receptor-like protein kinase FERONIA OS=Ara... 88.2 2e-16 sp|Q55GV3|PAKC_DICDI Serine/threonine-protein kinase pakC OS=Dict... 87.0 2e-16 sp|Q8H1G6|PTI11_ARATH PTI1-like tyrosine-protein kinase 1 OS=Arab... 85.9 2e-16 sp|Q60806|PLK3_MOUSE Serine/threonine-protein kinase PLK3 OS=Mus ... 87.8 3e-16 sp|O49339|PTI12_ARATH PTI1-like tyrosine-protein kinase 2 OS=Arab... 85.9 3e-16 sp|Q751E8|PHO85_EREGS Negative regulator of the PHO system OS=Ere... 84.7 3e-16 sp|Q9FM85|PBL16_ARATH Probable serine/threonine-protein kinase PB... 86.3 3e-16 sp|Q5AG71|HSL1_CANAL Serine/threonine-protein kinase HSL1 OS=Cand... 88.6 3e-16 sp|Q07832|PLK1_MOUSE Serine/threonine-protein kinase PLK1 OS=Mus ... 87.4 3e-16 sp|P51958|CDK1_CARAU Cyclin-dependent kinase 1 OS=Carassius aurat... 84.7 3e-16 sp|Q9M9E0|LRKS1_ARATH L-type lectin-domain containing receptor ki... 87.8 3e-16 sp|Q7ZUQ3|STK3_DANRE Serine/threonine-protein kinase 3 OS=Danio r... 87.0 3e-16 sp|C0LGW2|PAM74_ARATH Probable LRR receptor-like serine/threonine... 88.2 3e-16 sp|Q54EY4|DST3_DICDI Serine/threonine-protein kinase dst3 OS=Dict... 87.0 3e-16 sp|Q9LFT8|CDKC1_ARATH Cyclin-dependent kinase C-1 OS=Arabidopsis ... 87.0 3e-16 sp|U4PR86|MELK_CAEEL Maternal embryonic leucine zipper kinase OS=... 87.4 3e-16 sp|C0LGL4|Y2289_ARATH Probable LRR receptor-like serine/threonine... 87.8 3e-16 sp|Q84SN3|CDKF3_ORYSJ Cyclin-dependent kinase F-3 OS=Oryza sativa... 86.3 4e-16 sp|Q9FIZ3|GSO2_ARATH LRR receptor-like serine/threonine-protein k... 87.8 4e-16 sp|Q13188|STK3_HUMAN Serine/threonine-protein kinase 3 OS=Homo sa... 86.7 4e-16 sp|P83104|M3K7L_DROME Putative mitogen-activated protein kinase k... 85.5 4e-16 sp|Q90XC2|NEK8_DANRE Serine/threonine-protein kinase Nek8 OS=Dani... 87.4 4e-16 sp|Q1PDW3|LIPG1_ARATH Receptor-like kinase LIP1 OS=Arabidopsis th... 87.0 4e-16 sp|Q61UC4|KRAF1_CAEBR Raf homolog serine/threonine-protein kinase... 87.4 4e-16 sp|I1RNG8|ATG1_GIBZE Serine/threonine-protein kinase ATG1 OS=Gibb... 87.8 4e-16 sp|Q9LSE1|CDG1_ARATH Serine/threonine-protein kinase CDG1 OS=Arab... 85.9 4e-16 sp|Q9FYK0|TMK2_ARATH Receptor-like kinase TMK2 OS=Arabidopsis tha... 87.4 4e-16 sp|P0C8M8|CCR1_MAIZE Probable serine/threonine-protein kinase CCR... 87.0 4e-16 sp|F4IRW0|ATG1C_ARATH Serine/threonine-protein kinase ATG1c OS=Ar... 87.0 5e-16 sp|J4W0G2|ATG1_BEAB2 Serine/threonine-protein kinase ATG1 OS=Beau... 87.4 5e-16 sp|Q863I2|OXSR1_PIG Serine/threonine-protein kinase OSR1 OS=Sus s... 86.3 5e-16 sp|O81833|SD11_ARATH G-type lectin S-receptor-like serine/threoni... 87.0 5e-16 sp|Q54XL6|FRAY1_DICDI Serine/threonine-protein kinase fray1 OS=Di... 86.7 5e-16 sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo... 87.4 5e-16 sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens ... 87.0 5e-16 sp|Q0D541|WNK5_ORYSJ Probable serine/threonine-protein kinase WNK... 84.3 5e-16 sp|Q9FN93|Y5596_ARATH Probable LRR receptor-like serine/threonine... 87.0 5e-16 sp|Q1DN93|ATG1_COCIM Serine/threonine-protein kinase ATG1 OS=Cocc... 87.4 5e-16 sp|P32490|MKK1_YEAST MAP kinase kinase MKK1/SSP32 OS=Saccharomyce... 86.3 6e-16 sp|Q8W4P1|CDKC2_ARATH Cyclin-dependent kinase C-2 OS=Arabidopsis ... 85.9 6e-16 sp|Q94C40|CIPKH_ARATH CBL-interacting serine/threonine-protein ki... 85.5 6e-16 sp|Q96285|LRK55_ARATH L-type lectin-domain containing receptor ki... 86.7 7e-16 sp|Q9BYT3|STK33_HUMAN Serine/threonine-protein kinase 33 OS=Homo ... 85.9 7e-16 sp|Q8S8Y8|WNK6_ARATH Probable serine/threonine-protein kinase WNK... 86.3 7e-16 sp|Q8RXG3|M2K5_ARATH Mitogen-activated protein kinase kinase 5 OS... 84.3 7e-16 sp|Q4WJJ0|MKK2_ASPFU Mitogen-activated protein kinase kinae mkk2 ... 85.9 7e-16 sp|B0XPE4|MKK2_ASPFC Mitogen-activated protein kinase kinae mkk2 ... 85.9 7e-16 sp|C0LGN2|Y3148_ARATH Probable leucine-rich repeat receptor-like ... 87.0 7e-16 sp|Q9FG33|LRKS5_ARATH Probable L-type lectin-domain containing re... 86.3 7e-16 sp|Q54M77|ROCO8_DICDI Probable serine/threonine-protein kinase ro... 87.0 7e-16 sp|O59790|ARK1_SCHPO Serine/threonine-protein kinase ark1 OS=Schi... 84.3 7e-16 sp|Q8AYC9|CHK1_CHICK Serine/threonine-protein kinase Chk1 OS=Gall... 85.5 8e-16 sp|Q39203|SD22_ARATH G-type lectin S-receptor-like serine/threoni... 86.7 8e-16 sp|Q9CAL2|CRK3_ARATH Cysteine-rich receptor-like protein kinase 3... 86.3 8e-16 sp|P0CD62|LIMKB_DICDI Probable LIM domain-containing serine/threo... 86.7 8e-16 sp|O80397|M2K4_ARATH Mitogen-activated protein kinase kinase 4 OS... 84.3 8e-16 sp|Q8TGI1|ATG1_PICPA Serine/threonine-protein kinase ATG1 OS=Koma... 86.7 8e-16 sp|Q8H1E3|PBL17_ARATH Probable serine/threonine-protein kinase PB... 85.1 8e-16 sp|Q8L4H4|NORK_MEDTR Nodulation receptor kinase OS=Medicago trunc... 86.7 8e-16 sp|Q9R011|PLK3_RAT Serine/threonine-protein kinase PLK3 OS=Rattus... 86.3 8e-16 sp|C0LGR6|Y4291_ARATH Probable LRR receptor-like serine/threonine... 86.7 8e-16 sp|Q5R495|OXSR1_PONAB Serine/threonine-protein kinase OSR1 OS=Pon... 85.5 9e-16 sp|O95747|OXSR1_HUMAN Serine/threonine-protein kinase OSR1 OS=Hom... 85.5 9e-16 sp|C0LGU5|Y5457_ARATH Probable LRR receptor-like serine/threonine... 85.9 9e-16 sp|Q924X7|STK33_MOUSE Serine/threonine-protein kinase 33 OS=Mus m... 85.5 9e-16 sp|Q0D5R3|CRK6_ORYSJ Cysteine-rich receptor-like protein kinase 6... 86.3 9e-16 sp|Q65X23|WNK2_ORYSJ Probable serine/threonine-protein kinase WNK... 85.9 9e-16 sp|Q755C4|IPL1_EREGS Spindle assembly checkpoint kinase OS=Eremot... 84.0 9e-16 sp|Q59W62|GIN4_CANAL Serine/threonine-protein kinase GIN4 OS=Cand... 86.7 9e-16 sp|Q9SIB6|PBL6_ARATH Probable serine/threonine-protein kinase PBL... 84.7 1e-15 sp|Q9SEZ7|CIPKG_ARATH CBL-interacting serine/threonine-protein ki... 85.1 1e-15 sp|Q869W6|MYLKG_DICDI Probable myosin light chain kinase DDB_G027... 83.6 1e-15 sp|A2VDU3|M3K7_BOVIN Mitogen-activated protein kinase kinase kina... 85.5 1e-15 sp|P22216|RAD53_YEAST Serine/threonine-protein kinase RAD53 OS=Sa... 86.3 1e-15 sp|Q06309|CRK1_LEIME Cell division protein kinase 2 homolog CRK1 ... 82.8 1e-15 sp|O22834|LRK53_ARATH Probable L-type lectin-domain containing re... 85.9 1e-15 sp|Q5RFL3|M3K7_PONAB Mitogen-activated protein kinase kinase kina... 85.9 1e-15 sp|Q95ZQ4|AAPK2_CAEEL 5'-AMP-activated protein kinase catalytic s... 85.9 1e-15 sp|Q62073|M3K7_MOUSE Mitogen-activated protein kinase kinase kina... 85.5 1e-15 sp|O14098|CTK1_SCHPO CTD kinase subunit alpha OS=Schizosaccharomy... 85.5 1e-15 sp|P46551|CDK12_CAEEL Cyclin-dependent kinase 12 OS=Caenorhabditi... 85.9 1e-15 sp|P0C8E4|M3K7_RAT Mitogen-activated protein kinase kinase kinase... 85.5 1e-15 sp|Q75DK7|STE20_EREGS Serine/threonine-protein kinase STE20 OS=Er... 86.3 1e-15 sp|Q8K1R7|NEK9_MOUSE Serine/threonine-protein kinase Nek9 OS=Mus ... 86.3 1e-15 sp|O43318|M3K7_HUMAN Mitogen-activated protein kinase kinase kina... 85.5 1e-15 sp|P70218|M4K1_MOUSE Mitogen-activated protein kinase kinase kina... 85.9 1e-15 sp|P05986|KAPC_YEAST cAMP-dependent protein kinase type 3 OS=Sacc... 84.0 1e-15 sp|D4AE59|STK11_RAT Serine/threonine-protein kinase STK11 OS=Ratt... 84.3 1e-15 sp|Q8C015|PAK5_MOUSE Serine/threonine-protein kinase PAK 5 OS=Mus... 85.9 1e-15 sp|D4A280|PAK5_RAT Serine/threonine-protein kinase PAK 5 OS=Rattu... 85.9 1e-15 sp|Q9FIU5|CRLK1_ARATH Calcium/calmodulin-regulated receptor-like ... 84.7 1e-15 sp|Q9SGP2|HSL1_ARATH Receptor-like protein kinase HSL1 OS=Arabido... 86.3 1e-15 sp|Q6P3R8|NEK5_HUMAN Serine/threonine-protein kinase Nek5 OS=Homo... 85.9 1e-15 sp|C0LGQ5|GSO1_ARATH LRR receptor-like serine/threonine-protein k... 86.3 1e-15 sp|Q8VYT3|Y4052_ARATH Probable LRR receptor-like serine/threonine... 85.5 1e-15 sp|C0LGT5|Y5169_ARATH Probable LRR receptor-like serine/threonine... 85.9 1e-15 sp|Q9ZVP5|M3K18_ARATH Mitogen-activated protein kinase kinase kin... 83.2 1e-15 sp|Q0GGW5|STK11_CHICK Serine/threonine-protein kinase STK11 OS=Ga... 84.3 1e-15 sp|P70032|PLK1_XENLA Serine/threonine-protein kinase PLK1 OS=Xeno... 85.5 1e-15 sp|P93749|Y2197_ARATH Probable protein kinase At2g41970 OS=Arabid... 83.6 1e-15 sp|Q9M020|LRK63_ARATH Lectin-domain containing receptor kinase VI... 85.5 1e-15 sp|P18161|SPLB_DICDI Dual specificity protein kinase splB OS=Dict... 86.3 1e-15 sp|Q8LKZ1|NORK_PEA Nodulation receptor kinase OS=Pisum sativum OX... 85.9 1e-15 sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo... 85.5 1e-15 sp|Q9SY89|Y1661_ARATH Putative G-type lectin S-receptor-like seri... 85.9 2e-15 sp|Q9M1Z9|LRK58_ARATH Putative L-type lectin-domain containing re... 85.1 2e-15 sp|O75011|NAK1_SCHPO Serine/threonine-protein kinase nak1 OS=Schi... 85.5 2e-15 sp|O81832|Y4729_ARATH G-type lectin S-receptor-like serine/threon... 85.5 2e-15 sp|Q5Z6X0|CIPKP_ORYSJ CBL-interacting protein kinase 25 OS=Oryza ... 84.7 2e-15 sp|Q6CVA2|STE20_KLULA Serine/threonine-protein kinase STE20 OS=Kl... 85.9 2e-15 sp|Q3ULB5|PAK6_MOUSE Serine/threonine-protein kinase PAK 6 OS=Mus... 85.5 2e-15 sp|P62205|PLK1_XENTR Serine/threonine-protein kinase PLK1 OS=Xeno... 85.1 2e-15 sp|Q9P286|PAK5_HUMAN Serine/threonine-protein kinase PAK 5 OS=Hom... 85.5 2e-15 sp|C0LGG6|Y5189_ARATH Probable LRR receptor-like protein kinase A... 85.5 2e-15 sp|Q9FLW0|Y5241_ARATH Probable receptor-like protein kinase At5g2... 85.5 2e-15 sp|Q9M8J5|M2K8_ARATH Mitogen-activated protein kinase kinase 8 OS... 82.4 2e-15 sp|Q9C823|Y1523_ARATH C-type lectin receptor-like tyrosine-protei... 84.7 2e-15 sp|Q8S9L6|CRK29_ARATH Cysteine-rich receptor-like protein kinase ... 85.1 2e-15 sp|P24583|KPC1_YEAST Protein kinase C-like 1 OS=Saccharomyces cer... 85.9 2e-15 sp|Q9WTK7|STK11_MOUSE Serine/threonine-protein kinase STK11 OS=Mu... 84.0 2e-15 sp|Q9LFG1|Y3359_ARATH Putative leucine-rich repeat receptor-like ... 85.5 2e-15 sp|Q5JK68|CDKC2_ORYSJ Cyclin-dependent kinase C-2 OS=Oryza sativa... 84.7 2e-15 sp|Q0VD22|STK33_BOVIN Serine/threonine-protein kinase 33 OS=Bos t... 84.3 2e-15 sp|Q63531|KS6A1_RAT Ribosomal protein S6 kinase alpha-1 OS=Rattus... 85.1 2e-15 sp|O22187|Y2232_ARATH Probable receptor-like protein kinase At2g2... 85.5 2e-15 sp|Q9SXB5|Y1135_ARATH G-type lectin S-receptor-like serine/threon... 85.5 2e-15 sp|P43294|MHK_ARATH Serine/threonine-protein kinase MHK OS=Arabid... 84.0 2e-15 sp|Q6DE87|CHK1_XENLA Serine/threonine-protein kinase Chk1 OS=Xeno... 84.3 2e-15 sp|Q66HE5|NUAK2_RAT NUAK family SNF1-like kinase 2 OS=Rattus norv... 85.1 2e-15 sp|Q5JLD8|CIPK8_ORYSJ CBL-interacting protein kinase 8 OS=Oryza s... 84.0 2e-15 sp|Q5R8Z4|PAK6_PONAB Serine/threonine-protein kinase PAK 6 OS=Pon... 85.1 2e-15 sp|Q64303|PAK2_RAT Serine/threonine-protein kinase PAK 2 OS=Rattu... 84.3 2e-15 sp|Q9NQU5|PAK6_HUMAN Serine/threonine-protein kinase PAK 6 OS=Hom... 84.7 2e-15 sp|Q6FV07|IPL1_CANGA Spindle assembly checkpoint kinase OS=Candid... 82.8 2e-15 sp|Q6P9R2|OXSR1_MOUSE Serine/threonine-protein kinase OSR1 OS=Mus... 84.3 2e-15 sp|A0A8I5ZNK2|OXSR1_RAT Serine/threonine-protein kinase OSR1 OS=R... 84.3 2e-15 sp|Q6I5Y0|CDKC1_ORYSJ Cyclin-dependent kinase C-1 OS=Oryza sativa... 84.3 2e-15 sp|Q8GUH1|PUB33_ARATH U-box domain-containing protein 33 OS=Arabi... 85.1 2e-15 sp|C0LGG9|Y5344_ARATH Probable LRR receptor-like serine/threonine... 85.1 2e-15 sp|Q8CIN4|PAK2_MOUSE Serine/threonine-protein kinase PAK 2 OS=Mus... 84.3 2e-15 sp|Q9FX99|Y1497_ARATH Probable receptor-like protein kinase At1g4... 84.7 2e-15 sp|Q29502|PAK2_RABIT Serine/threonine-protein kinase PAK 2 OS=Ory... 84.3 2e-15 sp|Q4P5N0|STE20_USTMA Serine/threonine-protein kinase SMU1 OS=Ust... 84.7 2e-15 sp|Q7RAH3|CDPK1_PLAYO Calcium-dependent protein kinase 1 OS=Plasm... 84.3 3e-15 sp|C0LGU1|Y5374_ARATH Probable LRR receptor-like serine/threonine... 85.1 3e-15 sp|Q08E52|PAK1_BOVIN Serine/threonine-protein kinase PAK 1 OS=Bos... 84.3 3e-15 sp|Q9SXB8|Y1133_ARATH G-type lectin S-receptor-like serine/threon... 84.7 3e-15 sp|Q9LK35|THE1_ARATH Receptor-like protein kinase THESEUS 1 OS=Ar... 84.7 3e-15 sp|G5EGT9|RYK_CAEEL Inactive tyrosine-protein kinase RYK OS=Caeno... 84.3 3e-15 sp|P0CY24|STE20_CANAL Serine/threonine-protein kinase CST20 OS=Ca... 85.1 3e-15 sp|Q66GN2|LRK64_ARATH Lectin-domain containing receptor kinase VI... 84.7 3e-15 sp|O88643|PAK1_MOUSE Serine/threonine-protein kinase PAK 1 OS=Mus... 84.0 3e-15 sp|Q39030|KPK2_ARATH Serine/threonine-protein kinase AtPK2/AtPK19... 83.6 3e-15 sp|Q13153|PAK1_HUMAN Serine/threonine-protein kinase PAK 1 OS=Hom... 84.0 3e-15 sp|C4YRB7|STE20_CANAW Serine/threonine-protein kinase CST20 OS=Ca... 85.1 3e-15 sp|Q9LVP0|Y5639_ARATH Probable leucine-rich repeat receptor-like ... 85.1 3e-15 sp|Q9URY1|PPK16_SCHPO Serine/threonine-protein kinase ppk16 OS=Sc... 84.3 3e-15 sp|Q54Y90|Y0133_DICDI Probable serine/threonine-protein kinase DD... 85.1 3e-15 sp|P0CY23|STE20_CANAX Serine/threonine-protein kinase CST20 OS=Ca... 85.1 3e-15 sp|P35465|PAK1_RAT Serine/threonine-protein kinase PAK 1 OS=Rattu... 84.0 3e-15 sp|Q6C7U8|PHO85_YARLI Negative regulator of the PHO system OS=Yar... 81.3 3e-15 sp|A0A509AHB6|CDPK1_PLABA Calcium-dependent protein kinase 1 OS=P... 84.0 3e-15 sp|Q13177|PAK2_HUMAN Serine/threonine-protein kinase PAK 2 OS=Hom... 84.0 3e-15 sp|P93050|RKF3_ARATH Probable LRR receptor-like serine/threonine-... 84.3 3e-15 sp|Q8AXB4|PAK3_XENLA Serine/threonine-protein kinase PAK 3 OS=Xen... 84.0 3e-15 sp|P51839|GUC2D_RAT Guanylate cyclase 2D OS=Rattus norvegicus OX=... 85.1 3e-15 sp|Q17850|PK1_CAEEL Serine/threonine-protein kinase pak-1 OS=Caen... 84.0 3e-15 sp|C0LGH2|Y1561_ARATH Probable LRR receptor-like serine/threonine... 84.7 3e-15 sp|Q5SUV5|MYLK4_MOUSE Myosin light chain kinase family member 4 O... 82.8 3e-15 sp|Q03147|CDK7_MOUSE Cyclin-dependent kinase 7 OS=Mus musculus OX... 82.0 3e-15 sp|C0LGD9|Y1756_ARATH Probable LRR receptor-like serine/threonine... 84.3 4e-15 sp|P50613|CDK7_HUMAN Cyclin-dependent kinase 7 OS=Homo sapiens OX... 82.0 4e-15 sp|Q9LPZ3|Y1141_ARATH G-type lectin S-receptor-like serine/threon... 84.3 4e-15 sp|A8X0C4|PAR4_CAEBR Serine/threonine-protein kinase par-4 OS=Cae... 84.0 4e-15 sp|C0LGG8|Y5343_ARATH Probable LRR receptor-like serine/threonine... 84.7 4e-15 sp|Q9R0G8|NRK_MOUSE Nik-related protein kinase OS=Mus musculus OX... 84.7 4e-15 sp|Q6I5Q6|RK185_ORYSJ Receptor-like cytoplasmic kinase 185 OS=Ory... 83.2 4e-15 sp|A8R7E6|CERK1_ARATH Chitin elicitor receptor kinase 1 OS=Arabid... 84.0 4e-15 sp|Q9NWZ3|IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 ... 83.2 4e-15 sp|O80623|Y2393_ARATH Probable receptor-like protein kinase At2g3... 84.3 4e-15 sp|A9S5R3|M2K1C_PHYPA Mitogen-activated protein kinase kinase 1c ... 81.6 4e-15 sp|Q8LST2|WNK7_ARATH Probable serine/threonine-protein kinase WNK... 83.6 4e-15 sp|P47735|RLK5_ARATH Receptor-like protein kinase 5 OS=Arabidopsi... 84.3 4e-15 sp|O04086|Y1105_ARATH Probable receptor-like protein kinase At1g1... 84.0 4e-15 sp|Q08942|NRKA_TRYBB Putative serine/threonine-protein kinase A O... 82.8 4e-15 sp|Q92241|PHO85_KLULA Negative regulator of the PHO system OS=Klu... 80.9 4e-15 sp|Q9LEU7|CIPK5_ARATH CBL-interacting serine/threonine-protein ki... 82.8 4e-15 sp|Q9Z1W9|STK39_MOUSE STE20/SPS1-related proline-alanine-rich pro... 83.6 4e-15 sp|O14427|CLA4_CANAX Serine/threonine-protein kinase CLA4 OS=Cand... 84.3 4e-15 sp|Q54B33|PAKE_DICDI Serine/threonine-protein kinase pakE OS=Dict... 84.3 5e-15 sp|Q5APR8|CLA4_CANAL Serine/threonine-protein kinase CLA4 OS=Cand... 84.3 5e-15 sp|Q9UEW8|STK39_HUMAN STE20/SPS1-related proline-alanine-rich pro... 83.6 5e-15 sp|O88506|STK39_RAT STE20/SPS1-related proline-alanine-rich prote... 83.6 5e-15 sp|F4JEQ2|PBL23_ARATH Probable serine/threonine-protein kinase PB... 82.0 5e-15 sp|Q12263|GIN4_YEAST Serine/threonine-protein kinase GIN4 OS=Sacc... 84.3 5e-15 sp|A8X5H5|GSK3_CAEBR Glycogen synthase kinase-3 OS=Caenorhabditis... 81.6 5e-15 sp|Q8C078|KKCC2_MOUSE Calcium/calmodulin-dependent protein kinase... 83.6 5e-15 sp|Q15131|CDK10_HUMAN Cyclin-dependent kinase 10 OS=Homo sapiens ... 81.6 5e-15 sp|C0LGI2|Y1677_ARATH Probable LRR receptor-like serine/threonine... 84.3 5e-15 sp|O13839|FIN1_SCHPO G2-specific protein kinase fin1 OS=Schizosac... 84.0 5e-15 sp|O64778|Y1142_ARATH G-type lectin S-receptor-like serine/threon... 84.0 5e-15 sp|Q552C6|ZAK2_DICDI Dual specificity protein kinase zak2 OS=Dict... 83.6 5e-15 sp|O64477|Y2913_ARATH G-type lectin S-receptor-like serine/threon... 84.0 5e-15 sp|O23304|BLUS1_ARATH Serine/threonine-protein kinase BLUS1 OS=Ar... 82.8 5e-15 sp|Q86CS2|ATG1_DICDI Serine/threonine-protein kinase atg1 OS=Dict... 83.6 5e-15 sp|C0LGH3|Y5614_ARATH Probable LRR receptor-like serine/threonine... 84.0 5e-15 sp|Q9LUT0|CARK1_ARATH Receptor-like cytoplasmic kinase 1 OS=Arabi... 81.6 5e-15 sp|O88831|KKCC2_RAT Calcium/calmodulin-dependent protein kinase k... 83.2 5e-15 sp|O64771|Y1148_ARATH G-type lectin S-receptor-like serine/threon... 84.0 6e-15 sp|O61661|CHK1_DROME Serine/threonine-protein kinase grp OS=Droso... 82.8 6e-15 sp|Q8INB9|AKT1_DROME RAC serine/threonine-protein kinase OS=Droso... 83.6 6e-15 sp|Q621J7|ZYG1_CAEBR Probable serine/threonine-protein kinase zyg... 83.6 6e-15 sp|Q9LP51|CIPKI_ARATH CBL-interacting serine/threonine-protein ki... 83.2 6e-15 sp|Q8W1D5|CIPKP_ARATH CBL-interacting serine/threonine-protein ki... 82.8 6e-15 sp|Q8BPM2|M4K5_MOUSE Mitogen-activated protein kinase kinase kina... 84.0 6e-15 sp|Q9M342|WAKLP_ARATH Wall-associated receptor kinase-like 15 OS=... 83.6 6e-15 sp|Q9HFF4|PPK1_SCHPO Serine/threonine-protein kinase ppk1 OS=Schi... 84.0 6e-15 sp|Q01919|KIN4_YEAST Serine/threonine-protein kinase KIN4 OS=Sacc... 83.6 6e-15 sp|Q7RZD3|STE20_NEUCR Serine/threonine-protein kinase ste20 OS=Ne... 84.0 6e-15 sp|O04533|LRK52_ARATH Putative L-type lectin-domain containing re... 83.2 6e-15 sp|Q2TBL8|CDK10_BOVIN Cyclin-dependent kinase 10 OS=Bos taurus OX... 81.3 7e-15 sp|Q2VWQ3|STE20_TALMA Serine/threonine-protein kinase pakA OS=Tal... 83.2 7e-15 sp|Q8GYA4|CRK10_ARATH Cysteine-rich receptor-like protein kinase ... 83.2 7e-15 sp|Q15831|STK11_HUMAN Serine/threonine-protein kinase STK11 OS=Ho... 82.0 7e-15 sp|O88866|HUNK_MOUSE Hormonally up-regulated neu tumor-associated... 83.6 7e-15 sp|Q3UMM4|CDK10_MOUSE Cyclin-dependent kinase 10 OS=Mus musculus ... 81.3 7e-15 sp|P34722|KPC1_CAEEL Protein kinase C-like 1 OS=Caenorhabditis el... 83.2 7e-15 sp|Q9Y4K4|M4K5_HUMAN Mitogen-activated protein kinase kinase kina... 83.6 7e-15 sp|Q9U2Q9|GSK3_CAEEL Glycogen synthase kinase-3 OS=Caenorhabditis... 81.3 7e-15 sp|Q9W739|CDK1_RANDY Cyclin-dependent kinase 1 OS=Rana dybowskii ... 80.5 7e-15 sp|P48562|CLA4_YEAST Serine/threonine-protein kinase CLA4 OS=Sacc... 83.6 7e-15 sp|Q9LXA5|LRK91_ARATH L-type lectin-domain containing receptor ki... 83.2 7e-15 sp|Q55FS2|STK4L_DICDI Serine/threonine-protein kinase 4 homolog B... 83.6 8e-15 sp|Q8VCR8|MYLK2_MOUSE Myosin light chain kinase 2, skeletal/cardi... 83.2 8e-15 sp|Q55GE6|ROCO7_DICDI Probable serine/threonine-protein kinase ro... 84.0 8e-15 sp|Q8KY50|STKP_STREE Serine/threonine-protein kinase StkP OS=Stre... 83.2 8e-15 sp|Q6C3J2|IPL1_YARLI Spindle assembly checkpoint kinase OS=Yarrow... 81.3 8e-15 sp|Q9LHP4|RGI1_ARATH LRR receptor-like serine/threonine-protein k... 83.6 8e-15 sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo sapi... 83.2 8e-15 sp|Q9SXB4|Y1130_ARATH G-type lectin S-receptor-like serine/threon... 83.2 8e-15 sp|Q4WHP3|STE20_ASPFU Serine/threonine-protein kinase ste20 OS=As... 83.2 8e-15 sp|Q9SJG2|Y2296_ARATH Probable receptor-like protein kinase At2g4... 82.4 8e-15 sp|A9SR33|M2K1B_PHYPA Mitogen-activated protein kinase kinase 1b ... 80.9 8e-15 sp|Q8T0S6|HIPPO_DROME Serine/threonine-protein kinase hippo OS=Dr... 83.2 8e-15 sp|C0LGV0|Y5487_ARATH Probable LRR receptor-like serine/threonine... 83.2 8e-15 sp|P13185|KIN1_YEAST Serine/threonine protein kinase KIN1 OS=Sacc... 83.6 9e-15 sp|F1LP90|MINK1_RAT Misshapen-like kinase 1 OS=Rattus norvegicus ... 83.6 9e-15 sp|A0A2I0BVG8|CDPK1_PLAFO Calcium-dependent protein kinase 1 OS=P... 82.4 9e-15 sp|P62343|CDPK1_PLAFK Calcium-dependent protein kinase 1 OS=Plasm... 82.4 9e-15 sp|P62344|CDPK1_PLAF7 Calcium-dependent protein kinase 1 OS=Plasm... 82.4 9e-15 sp|Q7YQL3|PAK3_PONPY Serine/threonine-protein kinase PAK 3 OS=Pon... 82.8 9e-15 sp|Q7YQL4|PAK3_PANTR Serine/threonine-protein kinase PAK 3 OS=Pan... 82.8 9e-15 sp|O75914|PAK3_HUMAN Serine/threonine-protein kinase PAK 3 OS=Hom... 82.8 9e-15 sp|Q09170|CDS1_SCHPO Serine/threonine-protein kinase cds1 OS=Schi... 82.0 9e-15 sp|Q62829|PAK3_RAT Serine/threonine-protein kinase PAK 3 OS=Rattu... 82.4 9e-15 sp|Q942F3|BRI1_ORYSJ Brassinosteroid LRR receptor kinase BRI1 OS=... 83.6 9e-15 sp|O22971|CIPKD_ARATH CBL-interacting serine/threonine-protein ki... 82.4 9e-15 sp|O64781|Y1639_ARATH G-type lectin S-receptor-like serine/threon... 83.2 9e-15 sp|A4IFM7|MYLK2_BOVIN Myosin light chain kinase 2, skeletal/cardi... 82.8 9e-15 sp|Q8SRF5|Y823_ENCCU Probable cell division protein kinase ECU08_... 79.3 9e-15 sp|Q9LYN8|EMS1_ARATH Leucine-rich repeat receptor protein kinase ... 83.6 9e-15 sp|Q61036|PAK3_MOUSE Serine/threonine-protein kinase PAK 3 OS=Mus... 82.4 9e-15 sp|Q4KM47|CDK10_RAT Cyclin-dependent kinase 10 OS=Rattus norvegic... 80.9 9e-15 sp|P07313|MYLK2_RABIT Myosin light chain kinase 2, skeletal/cardi... 82.8 9e-15 sp|P34099|KAPC_DICDI cAMP-dependent protein kinase catalytic subu... 82.8 1e-14 sp|P45894|AAPK1_CAEEL 5'-AMP-activated protein kinase catalytic s... 82.4 1e-14 sp|O65479|CRK20_ARATH Putative cysteine-rich receptor-like protei... 82.8 1e-14 sp|Q8N4C8|MINK1_HUMAN Misshapen-like kinase 1 OS=Homo sapiens OX=... 83.6 1e-14 sp|Q03963|E2AK2_MOUSE Interferon-induced, double-stranded RNA-act... 82.4 1e-14 sp|Q96RR4|KKCC2_HUMAN Calcium/calmodulin-dependent protein kinase... 82.4 1e-14 sp|O08815|SLK_RAT STE20-like serine/threonine-protein kinase OS=R... 83.2 1e-14 sp|Q9JM52|MINK1_MOUSE Misshapen-like kinase 1 OS=Mus musculus OX=... 83.2 1e-14 sp|O80888|M3K17_ARATH Mitogen-activated protein kinase kinase kin... 80.9 1e-14 sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo sa... 82.0 1e-14 sp|Q9TXJ0|CMK1_CAEEL Calcium/calmodulin-dependent protein kinase ... 80.5 1e-14 sp|P24100|CDKA1_ARATH Cyclin-dependent kinase A-1 OS=Arabidopsis ... 79.7 1e-14 sp|Q9SYA0|Y1150_ARATH G-type lectin S-receptor-like serine/threon... 82.8 1e-14 sp|Q38868|CDPK9_ARATH Calcium-dependent protein kinase 9 OS=Arabi... 82.0 1e-14 sp|Q91ZN7|CHK1_RAT Serine/threonine-protein kinase Chk1 OS=Rattus... 81.6 1e-14 sp|Q8BRK8|AAPK2_MOUSE 5'-AMP-activated protein kinase catalytic s... 82.0 1e-14 sp|O54988|SLK_MOUSE STE20-like serine/threonine-protein kinase OS... 83.2 1e-14 sp|D7UPN3|RLK10_ORYSJ LysM domain receptor-like kinase 10 OS=Oryz... 82.4 1e-14 sp|Q09137|AAPK2_RAT 5'-AMP-activated protein kinase catalytic sub... 82.0 1e-14 sp|Q8RWZ5|SD25_ARATH G-type lectin S-receptor-like serine/threoni... 82.8 1e-14 sp|C0LGP2|MEE39_ARATH Probable LRR receptor-like serine/threonine... 82.8 1e-14 sp|Q8RXC8|RBK2_ARATH Receptor-like cytosolic serine/threonine-pro... 81.6 1e-14 sp|Q8S8S7|PUB34_ARATH U-box domain-containing protein 34 OS=Arabi... 82.8 1e-14 sp|P20689|MYLK2_RAT Myosin light chain kinase 2, skeletal/cardiac... 82.4 1e-14 sp|O70405|ULK1_MOUSE Serine/threonine-protein kinase ULK1 OS=Mus ... 82.8 1e-14 sp|Q54HC6|ARKA_DICDI Ankyrin repeat-containing protein kinase A O... 83.2 1e-14 sp|Q54G43|SHKE_DICDI Dual specificity protein kinase shkE OS=Dict... 82.4 1e-14 sp|Q6BVA0|IPL1_DEBHA Spindle assembly checkpoint kinase OS=Debary... 81.3 1e-14 sp|Q04735|CDK16_MOUSE Cyclin-dependent kinase 16 OS=Mus musculus ... 81.6 1e-14 sp|Q54MV2|MRKB_DICDI Probable serine/threonine-protein kinase MAR... 82.4 1e-14 sp|Q8GWJ7|CRK19_ARATH Cysteine-rich receptor-like protein kinase ... 82.4 1e-14 sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo... 81.6 1e-14 sp|O75385|ULK1_HUMAN Serine/threonine-protein kinase ULK1 OS=Homo... 82.8 1e-14 sp|Q5PU49|KPCD_CANLF Protein kinase C delta type OS=Canis lupus f... 82.4 1e-14 sp|Q60680|IKKA_MOUSE Inhibitor of nuclear factor kappa-B kinase s... 82.4 1e-14 sp|O55092|SLK_CAVPO STE20-like serine/threonine-protein kinase OS... 82.8 1e-14 sp|Q63686|CDK16_RAT Cyclin-dependent kinase 16 OS=Rattus norvegic... 81.6 1e-14 sp|P87248|ATG1_COLLN Serine/threonine-protein kinase ATG1 OS=Coll... 82.4 1e-14 sp|Q9UIK4|DAPK2_HUMAN Death-associated protein kinase 2 OS=Homo s... 80.5 1e-14 sp|Q9WUT3|KS6A2_MOUSE Ribosomal protein S6 kinase alpha-2 OS=Mus ... 82.4 2e-14 sp|Q0UY20|ATG1_PHANO Serine/threonine-protein kinase atg1 OS=Phae... 82.4 2e-14 sp|O64556|Y2923_ARATH Putative leucine-rich repeat receptor-like ... 82.4 2e-14 sp|Q97PA9|STKP_STRPN Serine/threonine-protein kinase StkP OS=Stre... 82.0 2e-14 sp|Q3ZDQ4|ATG1_PODAS Serine/threonine-protein kinase ATG1 OS=Podo... 82.4 2e-14 sp|Q8DNS0|STKP_STRR6 Serine/threonine-protein kinase StkP OS=Stre... 82.0 2e-14 sp|Q04J43|STKP_STRP2 Serine/threonine-protein kinase StkP OS=Stre... 82.0 2e-14 sp|Q7TSC3|NEK5_MOUSE Serine/threonine-protein kinase Nek5 OS=Mus ... 82.0 2e-14 sp|Q0WVM4|Y2239_ARATH Probable LRR receptor-like serine/threonine... 82.0 2e-14 sp|Q9FII5|TDR_ARATH Leucine-rich repeat receptor-like protein kin... 82.4 2e-14 sp|O22476|BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 OS=Ara... 82.4 2e-14 sp|G5ECH7|CDK5_CAEEL Cyclin-dependent-like kinase 5 OS=Caenorhabd... 79.0 2e-14 sp|Q9SHI2|Y1723_ARATH Leucine-rich repeat receptor-like serine/th... 82.4 2e-14 sp|Q28948|AAPK2_PIG 5'-AMP-activated protein kinase catalytic sub... 81.6 2e-14 sp|P54646|AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic s... 81.6 2e-14 sp|P34112|CDK1_DICDI Cyclin-dependent kinase 1 OS=Dictyostelium d... 79.0 2e-14 sp|Q4WVG0|PKCA_ASPFU Protein kinase C OS=Aspergillus fumigatus (s... 82.4 2e-14 sp|Q9ZRF9|RPK1_ARATH Probable LRR receptor-like serine/threonine-... 81.6 2e-14 sp|Q00536|CDK16_HUMAN Cyclin-dependent kinase 16 OS=Homo sapiens ... 81.3 2e-14 sp|A0A0U1RPR8|GUC2D_MOUSE Guanylate cyclase D OS=Mus musculus OX=... 82.4 2e-14 sp|Q6ZLP5|CIPKN_ORYSJ CBL-interacting protein kinase 23 OS=Oryza ... 80.9 2e-14 sp|Q5RD00|AAPK2_PONAB 5'-AMP-activated protein kinase catalytic s... 81.6 2e-14 sp|Q9C6P3|CDPKX_ARATH Calcium-dependent protein kinase 33 OS=Arab... 81.3 2e-14 sp|Q54WJ0|STK11_DICDI Serine/threonine-protein kinase stk11 homol... 81.6 2e-14 sp|P42818|KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6 ... 80.9 2e-14 sp|Q0D4B2|CIPKL_ORYSJ CBL-interacting protein kinase 21 OS=Oryza ... 81.3 2e-14 sp|Q9ZR08|Y4230_ARATH G-type lectin S-receptor-like serine/threon... 82.0 2e-14 sp|Q641K5|NUAK1_MOUSE NUAK family SNF1-like kinase 1 OS=Mus muscu... 81.6 2e-14 sp|P13186|KIN2_YEAST Serine/threonine-protein kinase KIN2 OS=Sacc... 82.4 2e-14 sp|Q8BZ25|ANKK1_MOUSE Ankyrin repeat and protein kinase domain-co... 82.0 2e-14 sp|Q9SR87|LRK61_ARATH Probable L-type lectin-domain containing re... 81.6 2e-14 sp|Q13233|M3K1_HUMAN Mitogen-activated protein kinase kinase kina... 82.4 2e-14 sp|A3B529|CIPKS_ORYSJ CBL-interacting protein kinase 28 OS=Oryza ... 80.5 2e-14 sp|Q69Q47|CIPKO_ORYSJ CBL-interacting protein kinase 24 OS=Oryza ... 80.9 2e-14 sp|Q9SYS3|CRK40_ARATH Cysteine-rich receptor-like protein kinase ... 81.6 2e-14 sp|Q39192|SRK2D_ARATH Serine/threonine-protein kinase SRK2D OS=Ar... 79.7 2e-14 sp|P25323|MYLKA_DICDI Myosin light chain kinase A OS=Dictyosteliu... 79.0 2e-14 sp|Q6UD73|LYK3_MEDTR LysM domain receptor-like kinase 3 OS=Medica... 81.6 2e-14 sp|Q9S9M2|WAKLD_ARATH Wall-associated receptor kinase-like 4 OS=A... 81.6 2e-14 sp|Q54RB2|CDK11_DICDI Cyclin-dependent kinase 11 OS=Dictyostelium... 79.7 2e-14 sp|P0DL10|TD1_MAIZE Leucine-rich repeat receptor-like kinase prot... 82.0 2e-14 sp|Q9LZU4|CRK4_ARATH Cysteine-rich receptor-like protein kinase 4... 81.6 2e-14 sp|Q9ZVR7|PSKR1_ARATH Phytosulfokine receptor 1 OS=Arabidopsis th... 82.0 2e-14 sp|P07527|WEE1_SCHPO Mitosis inhibitor protein kinase wee1 OS=Sch... 82.0 2e-14 sp|P13863|CDK1_CHICK Cyclin-dependent kinase 1 OS=Gallus gallus O... 79.0 2e-14 sp|Q9H1R3|MYLK2_HUMAN Myosin light chain kinase 2, skeletal/cardi... 81.3 2e-14 sp|Q924I2|M4K3_RAT Mitogen-activated protein kinase kinase kinase... 81.6 2e-14 sp|Q91604|STK11_XENLA Serine/threonine-protein kinase stk11 OS=Xe... 80.5 2e-14 sp|Q9LFV3|CRLK2_ARATH Calcium/calmodulin-regulated receptor-like ... 80.5 2e-14 sp|P54645|AAPK1_RAT 5'-AMP-activated protein kinase catalytic sub... 81.3 2e-14 sp|O42632|KPC1_COCHE Protein kinase C-like OS=Cochliobolus hetero... 82.0 2e-14 sp|Q38772|CDC2A_ANTMA Cell division control protein 2 homolog A O... 78.6 3e-14 sp|Q9FJ55|CIPKJ_ARATH CBL-interacting serine/threonine-protein ki... 80.9 3e-14 sp|Q5GIG6|TNI3K_MOUSE Serine/threonine-protein kinase TNNI3K OS=M... 81.6 3e-14 sp|Q9ZWC8|BRL1_ARATH Serine/threonine-protein kinase BRI1-like 1 ... 82.0 3e-14 sp|Q8VDF3|DAPK2_MOUSE Death-associated protein kinase 2 OS=Mus mu... 79.7 3e-14 sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic s... 81.3 3e-14 sp|O35280|CHK1_MOUSE Serine/threonine-protein kinase Chk1 OS=Mus ... 80.9 3e-14 sp|F4I1N8|ATG1T_ARATH Serine/threonine-protein kinase ATG1t OS=Ar... 80.1 3e-14 sp|Q5EG47|AAPK1_MOUSE 5'-AMP-activated protein kinase catalytic s... 81.3 3e-14 sp|Q5JLQ9|CIPKU_ORYSJ CBL-interacting protein kinase 30 OS=Oryza ... 80.9 3e-14 sp|P51952|CDK7_RAT Cyclin-dependent kinase 7 (Fragment) OS=Rattus... 79.0 3e-14 sp|P10665|KS6AA_XENLA Ribosomal protein S6 kinase 2 alpha OS=Xeno... 81.6 3e-14 sp|Q7TQP6|TNI3K_RAT Serine/threonine-protein kinase TNNI3K OS=Rat... 81.6 3e-14 sp|O80939|LRK41_ARATH L-type lectin-domain containing receptor ki... 81.3 3e-14 sp|Q9SNA3|Y3463_ARATH Putative receptor-like protein kinase At3g4... 81.6 3e-14 sp|O43293|DAPK3_HUMAN Death-associated protein kinase 3 OS=Homo s... 80.5 3e-14 sp|Q19469|SAD1_CAEEL Serine/threonine kinase SAD-1 OS=Caenorhabdi... 81.6 3e-14 sp|Q68UT7|HUNK_PANTR Hormonally up-regulated neu tumor-associated... 81.3 3e-14 sp|Q9Y572|RIPK3_HUMAN Receptor-interacting serine/threonine-prote... 80.9 3e-14 sp|P18265|GSK3A_RAT Glycogen synthase kinase-3 alpha OS=Rattus no... 80.5 3e-14 sp|Q5RDH5|AAPK1_PONAB 5'-AMP-activated protein kinase catalytic s... 80.9 3e-14 sp|Q41639|CDC2_VIGAC Cell division control protein 2 homolog OS=V... 78.2 3e-14 sp|P53349|M3K1_MOUSE Mitogen-activated protein kinase kinase kina... 81.6 3e-14 sp|Q753D9|PKH3_EREGS Serine/threonine-protein kinase PKH3 OS=Erem... 81.3 3e-14 sp|Q2V419|CKB12_ARATH Cyclin-dependent kinase B1-2 OS=Arabidopsis... 78.6 3e-14 sp|Q9XEC8|CRK38_ARATH Cysteine-rich receptor-like protein kinase ... 81.3 3e-14 sp|Q9SA72|Y1357_ARATH Probable receptor-like protein kinase At1g3... 81.3 3e-14 sp|P18652|KS6AA_CHICK Ribosomal protein S6 kinase 2 alpha OS=Gall... 81.3 3e-14 sp|Q8BZN4|NUAK2_MOUSE NUAK family SNF1-like kinase 2 OS=Mus muscu... 80.9 3e-14 sp|P57058|HUNK_HUMAN Hormonally up-regulated neu tumor-associated... 81.3 3e-14 sp|Q75V57|SAPK9_ORYSJ Serine/threonine-protein kinase SAPK9 OS=Or... 79.3 3e-14 sp|Q7Z2Y5|NRK_HUMAN Nik-related protein kinase OS=Homo sapiens OX... 81.6 3e-14 sp|O08644|EPHB6_MOUSE Ephrin type-B receptor 6 OS=Mus musculus OX... 81.6 3e-14 sp|Q9LN59|WAKLK_ARATH Putative wall-associated receptor kinase-li... 81.3 3e-14 sp|Q15349|KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 OS=Homo... 81.3 3e-14 sp|P06244|KAPA_YEAST cAMP-dependent protein kinase type 1 OS=Sacc... 79.7 3e-14 sp|Q99JP0|M4K3_MOUSE Mitogen-activated protein kinase kinase kina... 81.3 4e-14 sp|O04534|LRK51_ARATH Putative L-type lectin-domain containing re... 80.9 4e-14 sp|Q9SYS7|CRK39_ARATH Putative cysteine-rich receptor-like protei... 80.9 4e-14 sp|Q6BNF3|STE20_DEBHA Serine/threonine-protein kinase STE20 OS=De... 81.3 4e-14 sp|Q75H77|SAPKA_ORYSJ Serine/threonine-protein kinase SAPK10 OS=O... 79.3 4e-14 sp|Q9SA25|WAKLG_ARATH Wall-associated receptor kinase-like 8 OS=A... 80.9 4e-14 sp|Q9Y884|SKH1_SCHPO MAP kinase kinase skh1/pek1 OS=Schizosacchar... 79.0 4e-14 sp|C0LGG7|Y1534_ARATH Probable LRR receptor-like serine/threonine... 81.3 4e-14 sp|A0A1D6E0S8|WAK17_MAIZE Wall-associated receptor kinase 17 OS=Z... 81.3 4e-14 sp|O65472|CRK12_ARATH Putative cysteine-rich receptor-like protei... 80.9 4e-14 sp|Q8IVH8|M4K3_HUMAN Mitogen-activated protein kinase kinase kina... 81.3 4e-14 sp|Q8RY67|WAKLO_ARATH Wall-associated receptor kinase-like 14 OS=... 80.9 4e-14 sp|O15111|IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase s... 80.9 4e-14 sp|Q8CFH6|SIK2_MOUSE Serine/threonine-protein kinase SIK2 OS=Mus ... 81.3 4e-14 sp|Q8GYQ5|MPK12_ARATH Mitogen-activated protein kinase 12 OS=Arab... 79.0 4e-14 sp|Q6C3D7|STE20_YARLI Serine/threonine-protein kinase STE20 OS=Ya... 81.3 4e-14 sp|Q9LDI3|CIPKO_ARATH CBL-interacting serine/threonine-protein ki... 79.7 5e-14 sp|Q21029|NSY1_CAEEL Mitogen-activated protein kinase kinase kina... 81.3 5e-14 sp|Q54GY6|KXCA_DICDI Kinase and exchange factor for Rac A OS=Dict... 81.3 5e-14 sp|P34556|CDK1_CAEEL Cyclin-dependent kinase 1 OS=Caenorhabditis ... 78.6 5e-14 sp|Q6PDN3|MYLK_MOUSE Myosin light chain kinase, smooth muscle OS=... 81.3 5e-14 sp|Q62925|M3K1_RAT Mitogen-activated protein kinase kinase kinase... 81.3 5e-14 sp|Q5REX1|SIK2_PONAB Serine/threonine-protein kinase SIK2 OS=Pong... 80.9 5e-14 sp|Q7X8C5|WAKLB_ARATH Wall-associated receptor kinase-like 2 OS=A... 80.5 5e-14 sp|Q39202|RLK1_ARATH G-type lectin S-receptor-like serine/threoni... 80.5 5e-14 sp|P50528|PLO1_SCHPO Serine/threonine-protein kinase plo1 OS=Schi... 80.5 5e-14 sp|Q52EB3|ATG1_PYRO7 Serine/threonine-protein kinase ATG1 OS=Pyri... 80.9 5e-14 sp|A9TF79|SRK2A_PHYPA Serine/threonine-protein kinase SRK2A OS=Ph... 78.6 5e-14 sp|P34101|FHKC_DICDI Probable serine/threonine-protein kinase fhk... 80.1 5e-14 sp|Q8N5S9|KKCC1_HUMAN Calcium/calmodulin-dependent protein kinase... 79.7 5e-14 sp|Q9LUL4|SRF7_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 7 OS=Arab... 80.5 5e-14 sp|Q9DG98|CDK1_ORYLU Cyclin-dependent kinase 1 OS=Oryzias luzonen... 77.8 6e-14 sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS... 80.9 6e-14 sp|Q21734|KS6A1_CAEEL Putative ribosomal protein S6 kinase alpha-... 80.5 6e-14 sp|G4N6Z6|MKK2_PYRO7 Mitogen-activated protein kinase kinae MKK2 ... 79.7 6e-14 sp|Q9DGD3|CDK1_ORYLA Cyclin-dependent kinase 1 OS=Oryzias latipes... 77.8 6e-14 sp|Q95KV1|IKKA_BOVIN Inhibitor of nuclear factor kappa-B kinase s... 80.5 6e-14 sp|Q9LIG2|RLK6_ARATH Receptor-like protein kinase At3g21340 OS=Ar... 80.5 6e-14 sp|Q69JN6|BRL1_ORYSJ Brassinosteroid LRR receptor kinase BRL1 OS=... 80.9 6e-14 sp|Q9SYM9|Y1853_ARATH Receptor-like serine/threonine-protein kina... 78.6 6e-14 sp|Q9SI06|Y5573_ARATH Putative leucine-rich repeat receptor-like ... 80.5 6e-14 sp|Q5XIT0|CDKL2_RAT Cyclin-dependent kinase-like 2 OS=Rattus norv... 79.7 6e-14 sp|Q38773|CDC2B_ANTMA Cell division control protein 2 homolog B (... 77.4 6e-14 sp|Q8BGW6|ST32A_MOUSE Serine/threonine-protein kinase 32A OS=Mus ... 79.0 6e-14 sp|Q6ZCZ2|BRL3_ORYSJ Brassinosteroid LRR receptor kinase BRL3 OS=... 80.9 6e-14 sp|Q9M345|LRK42_ARATH L-type lectin-domain containing receptor ki... 80.1 6e-14 sp|O65405|CRK28_ARATH Cysteine-rich receptor-like protein kinase ... 80.1 6e-14 sp|Q54XX5|Y9849_DICDI Probable serine/threonine-protein kinase DD... 80.5 6e-14 sp|Q9TZM3|LRK1_CAEEL Leucine-rich repeat serine/threonine-protein... 80.9 6e-14 sp|Q8VBY2|KKCC1_MOUSE Calcium/calmodulin-dependent protein kinase... 79.7 6e-14 sp|P52389|CDC2_VIGUN Cell division control protein 2 homolog OS=V... 77.4 6e-14 sp|Q6EU49|WNK4_ORYSJ Probable serine/threonine-protein kinase WNK... 80.1 6e-14 sp|Q9DGA2|CDK1_ORYJA Cyclin-dependent kinase 1 OS=Oryzias javanic... 77.4 6e-14 sp|O49717|CDPKF_ARATH Calcium-dependent protein kinase 15 OS=Arab... 79.7 7e-14 sp|Q8GUQ5|BRI1_SOLLC Brassinosteroid LRR receptor kinase OS=Solan... 80.5 7e-14 sp|Q02723|RKIN1_SECCE Carbon catabolite-derepressing protein kina... 79.7 7e-14 sp|Q7Z8E9|STE20_PYRO7 Serine/threonine-protein kinase MST20 OS=Py... 80.5 7e-14 sp|Q9LX29|ACR4L_ARATH Serine/threonine-protein kinase-like protei... 80.5 7e-14 sp|P97756|KKCC1_RAT Calcium/calmodulin-dependent protein kinase k... 79.7 7e-14 sp|O64784|Y1136_ARATH G-type lectin S-receptor-like serine/threon... 80.5 7e-14 sp|Q9LJF3|BRL3_ARATH Receptor-like protein kinase BRI1-like 3 OS=... 80.5 7e-14 sp|F4ICB6|IBS1_ARATH Protein IMPAIRED IN BABA-INDUCED STERILITY 1... 80.1 7e-14 sp|P87253|KPC1_NEUCR Protein kinase C-like OS=Neurospora crassa (... 80.5 7e-14 sp|Q8SQW2|CTK1_ENCCU Probable CTD kinase subunit alpha homolog OS... 77.8 7e-14 sp|P10666|KS6AB_XENLA Ribosomal protein S6 kinase 2 beta OS=Xenop... 79.7 8e-14 sp|O81069|Y2899_ARATH Probable leucine-rich repeat receptor-like ... 80.1 8e-14 sp|Q2NL51|GSK3A_MOUSE Glycogen synthase kinase-3 alpha OS=Mus mus... 79.3 8e-14 sp|P34117|CDK5_DICDI Cyclin-dependent kinase 5 homolog OS=Dictyos... 77.0 8e-14 sp|P50526|SSP1_SCHPO Serine/threonine-protein kinase ssp1 OS=Schi... 79.7 8e-14 sp|P51817|PRKX_HUMAN cAMP-dependent protein kinase catalytic subu... 78.2 8e-14 sp|Q5YJC2|GSK3B_SPECI Glycogen synthase kinase-3 beta OS=Spermoph... 79.0 8e-14 sp|Q9FZB8|Y5181_ARATH Probable LRR receptor-like serine/threonine... 80.1 8e-14 sp|A8X6H4|CMK1_CAEBR Calcium/calmodulin-dependent protein kinase ... 78.2 8e-14 sp|Q55GG4|Y9847_DICDI Probable serine/threonine-protein kinase DD... 80.5 8e-14 sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo... 80.1 8e-14 sp|O54784|DAPK3_MOUSE Death-associated protein kinase 3 OS=Mus mu... 79.0 8e-14 sp|Q9C7T7|CEPR2_ARATH Receptor protein-tyrosine kinase CEPR2 OS=A... 80.1 8e-14 sp|Q9SKB2|SBIR1_ARATH Leucine-rich repeat receptor-like serine/th... 79.7 8e-14 sp|Q7XR88|STRK1_ORYSJ Salt tolerance receptor-like cytoplasmic ki... 78.2 8e-14 sp|A2XW02|STRK1_ORYSI Salt tolerance receptor-like cytoplasmic ki... 78.2 8e-14 sp|P48609|CDK5_DROME Cyclin-dependent kinase 5 homolog OS=Drosoph... 77.0 8e-14 sp|P49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta OS=Homo sap... 78.6 8e-14 sp|Q14164|IKKE_HUMAN Inhibitor of nuclear factor kappa-B kinase s... 79.7 8e-14 sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo... 79.7 9e-14 sp|O95819|M4K4_HUMAN Mitogen-activated protein kinase kinase kina... 80.5 9e-14 sp|P18654|KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 OS=Mus ... 79.7 9e-14 sp|Q9WV60|GSK3B_MOUSE Glycogen synthase kinase-3 beta OS=Mus musc... 78.6 9e-14 sp|P28867|KPCD_MOUSE Protein kinase C delta type OS=Mus musculus ... 79.7 9e-14 sp|P54666|CC2H3_TRYBB Cell division control protein 2 homolog 3 O... 77.4 9e-14 sp|Q9C8I6|IOS1_ARATH LRR receptor-like serine/threonine-protein k... 80.1 9e-14 sp|Q9QUK0|CDKL2_MOUSE Cyclin-dependent kinase-like 2 OS=Mus muscu... 79.3 9e-14 sp|Q93Z30|BHP_ARATH Serine/threonine-protein kinase 12 OS=Arabido... 79.0 9e-14 sp|Q8BG48|ST17B_MOUSE Serine/threonine-protein kinase 17B OS=Mus ... 78.2 9e-14 sp|Q8VYA3|WAKLJ_ARATH Wall-associated receptor kinase-like 10 OS=... 79.7 9e-14 sp|O88764|DAPK3_RAT Death-associated protein kinase 3 OS=Rattus n... 79.0 9e-14 sp|Q9TTK0|CDKL2_RABIT Cyclin-dependent kinase-like 2 OS=Oryctolag... 79.3 9e-14 sp|Q55DD4|PAKD_DICDI Serine/threonine-protein kinase pakD OS=Dict... 80.1 9e-14 sp|P12965|MOS_XENLA Serine/threonine-protein kinase mos OS=Xenopu... 77.8 9e-14 sp|O22932|CIPKB_ARATH CBL-interacting serine/threonine-protein ki... 78.6 1e-13 sp|Q8C0V7|SMKW_MOUSE Putative sperm motility kinase W OS=Mus musc... 79.0 1e-13 sp|P06493|CDK1_HUMAN Cyclin-dependent kinase 1 OS=Homo sapiens OX... 77.0 1e-13 sp|Q8S8Y9|WNK2_ARATH Serine/threonine-protein kinase WNK2 OS=Arab... 79.3 1e-13 sp|P48734|CDK1_BOVIN Cyclin-dependent kinase 1 OS=Bos taurus OX=9... 77.0 1e-13 sp|Q12469|SKM1_YEAST Serine/threonine-protein kinase SKM1 OS=Sacc... 79.7 1e-13 sp|Q93ZS4|NIK3_ARATH Protein NSP-INTERACTING KINASE 3 OS=Arabidop... 79.3 1e-13 sp|Q9FJ54|CIPKK_ARATH CBL-interacting serine/threonine-protein ki... 78.6 1e-13 sp|Q7Y0B9|SAPK8_ORYSJ Serine/threonine-protein kinase SAPK8 OS=Or... 77.8 1e-13 sp|P93101|CDC2_OXYRB Cell division control protein 2 homolog OS=O... 76.6 1e-13 sp|P35567|CDK1A_XENLA Cyclin-dependent kinase 1-A OS=Xenopus laev... 77.0 1e-13 sp|Q55CL6|MP2K1_DICDI Dual specificity mitogen-activated protein ... 79.3 1e-13 sp|X5M8U1|GCY17_CAEEL Receptor-type guanylate cyclase gcy-17 OS=C... 79.7 1e-13 sp|Q5WA76|PUB70_ORYSJ U-box domain-containing protein 70 OS=Oryza... 79.7 1e-13 sp|P23572|CDK1_DROME Cyclin-dependent kinase 1 OS=Drosophila mela... 76.6 1e-13 sp|Q8SRU0|CSK2A_ENCCU Probable casein kinase II subunit alpha hom... 77.0 1e-13 sp|Q5N942|SAPK4_ORYSJ Serine/threonine-protein kinase SAPK4 OS=Or... 77.8 1e-13 sp|P28582|CDPK_DAUCA Calcium-dependent protein kinase OS=Daucus c... 79.0 1e-13 sp|Q03002|FRK1_YEAST Fatty acyl-CoA synthetase and RNA processing... 79.7 1e-13 sp|Q6FN53|STE20_CANGA Serine/threonine-protein kinase STE20 OS=Ca... 79.7 1e-13 sp|Q92772|CDKL2_HUMAN Cyclin-dependent kinase-like 2 OS=Homo sapi... 78.6 1e-13 sp|Q16975|KPC2_APLCA Calcium-independent protein kinase C OS=Aply... 79.3 1e-13 sp|P19525|E2AK2_HUMAN Interferon-induced, double-stranded RNA-act... 79.0 1e-13 sp|O81292|LRK43_ARATH L-type lectin-domain containing receptor ki... 79.3 1e-13 sp|Q8VYY5|NCRK_ARATH Receptor-like serine/threonine-protein kinas... 79.0 1e-13 sp|Q940H6|SRK2E_ARATH Serine/threonine-protein kinase SRK2E OS=Ar... 77.4 1e-13 sp|Q5R754|CDKL2_PONAB Cyclin-dependent kinase-like 2 OS=Pongo abe... 78.6 1e-13 sp|Q8IBS5|CDPK4_PLAF7 Calcium-dependent protein kinase 4 OS=Plasm... 79.0 1e-13 sp|O23082|CRK44_ARATH Cysteine-rich receptor-like protein kinase ... 77.8 1e-13 sp|Q9S7U9|M2K2_ARATH Mitogen-activated protein kinase kinase 2 OS... 77.4 1e-13 sp|Q4R7T5|CDKL2_MACFA Cyclin-dependent kinase-like 2 OS=Macaca fa... 79.0 1e-13 sp|Q99014|KPC1_HYPJE Protein kinase C-like OS=Hypocrea jecorina O... 79.7 1e-13 sp|Q54WW7|Y0010_DICDI Probable serine/threonine-protein kinase DD... 79.3 1e-13 sp|Q2PQN9|CDK5_GLOMM Cyclin-dependent kinase 5 homolog OS=Glossin... 76.3 1e-13 sp|Q9FXF2|RKF1_ARATH Probable LRR receptor-like serine/threonine-... 79.7 1e-13 sp|P83510|TNIK_MOUSE Traf2 and NCK-interacting protein kinase OS=... 79.7 1e-13 sp|Q9FIF1|LRK21_ARATH Probable L-type lectin-domain containing re... 79.3 1e-13 sp|O95382|M3K6_HUMAN Mitogen-activated protein kinase kinase kina... 79.7 1e-13 sp|Q39086|SD17_ARATH Receptor-like serine/threonine-protein kinas... 79.3 1e-13 sp|Q9FHG4|LRKS7_ARATH Probable L-type lectin-domain containing re... 79.0 1e-13 sp|Q9DGA5|CDK1_ORYCU Cyclin-dependent kinase 1 OS=Oryzias curvino... 76.6 1e-13 sp|P11681|ABL_CALVI Tyrosine-protein kinase ABL (Fragment) OS=Cal... 70.1 1e-13 sp|Q9IA88|SIK2_CHICK Serine/threonine-protein kinase SIK2 OS=Gall... 79.3 1e-13 sp|O49318|Y2317_ARATH Probable leucine-rich repeat receptor-like ... 79.3 1e-13 sp|Q9FIF0|LRK22_ARATH Putative L-type lectin-domain containing re... 79.0 1e-13 sp|P0C5D6|SAPK3_ORYSJ Serine/threonine-protein kinase SAPK3 OS=Or... 77.0 1e-13 sp|A2ZAB5|SAPK3_ORYSI Serine/threonine-protein kinase SAPK3 OS=Or... 77.0 1e-13 sp|Q9XEC7|CRK37_ARATH Cysteine-rich receptor-like protein kinase ... 79.0 1e-13 sp|P39951|CDK1_RAT Cyclin-dependent kinase 1 OS=Rattus norvegicus... 76.3 1e-13 sp|Q9SN43|CIPKC_ARATH CBL-interacting serine/threonine-protein ki... 78.6 1e-13 sp|Q5BBL3|STE20_EMENI Serine/threonine-protein kinase ste20 OS=Em... 79.3 1e-13 sp|P11440|CDK1_MOUSE Cyclin-dependent kinase 1 OS=Mus musculus OX... 76.3 1e-13 sp|Q9ZVM9|Y1461_ARATH Probable serine/threonine-protein kinase At... 78.6 1e-13 sp|Q7XUF4|CDKG2_ORYSJ Cyclin-dependent kinase G-2 OS=Oryza sativa... 79.0 1e-13 sp|A2XUW1|CDKG2_ORYSI Cyclin-dependent kinase G-2 OS=Oryza sativa... 79.0 1e-13 sp|Q940A2|P2C31_ARATH Protein kinase and PP2C-like domain-contain... 79.0 2e-13 sp|O74536|SNF1_SCHPO SNF1-like protein kinase ssp2 OS=Schizosacch... 78.6 2e-13 sp|Q8H1D6|RBK1_ARATH Receptor-like cytosolic serine/threonine-pro... 78.2 2e-13 sp|Q6ICW6|WNK11_ARATH Probable serine/threonine-protein kinase WN... 76.6 2e-13 >sp|P29597|TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 OS=Homo sapiens OX=9606 GN=TYK2 PE=1 SV=3 Length=1187 Score = 2455 bits (6362), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1187/1187 (100%), Positives = 1187/1187 (100%), Gaps = 0/1187 (0%) Query 1 MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI 60 MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI Sbjct 1 MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI 60 Query 61 AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREP 120 AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREP Sbjct 61 AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREP 120 Query 121 AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFK 180 AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFK Sbjct 121 AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFK 180 Query 181 NESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRR 240 NESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRR Sbjct 181 NESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRR 240 Query 241 FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP 300 FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP Sbjct 241 FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP 300 Query 301 TDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHK 360 TDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHK Sbjct 301 TDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHK 360 Query 361 AVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLV 420 AVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLV Sbjct 361 AVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLV 420 Query 421 DGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP 480 DGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP Sbjct 421 DGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP 480 Query 481 YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA 540 YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA Sbjct 481 YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA 540 Query 541 GDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTR 600 GDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTR Sbjct 541 GDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTR 600 Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS Sbjct 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS Sbjct 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA Sbjct 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ Sbjct 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI Sbjct 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII Sbjct 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI Sbjct 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY Sbjct 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC Sbjct 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC 1187 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC Sbjct 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC 1187 >sp|Q9R117|TYK2_MOUSE Non-receptor tyrosine-protein kinase TYK2 OS=Mus musculus OX=10090 GN=Tyk2 PE=1 SV=3 Length=1184 Score = 1919 bits (4970), Expect = 0.0, Method: Compositional matrix adjust. Identities = 939/1177 (80%), Positives = 1023/1177 (87%), Gaps = 10/1177 (1%) Query 12 SKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCF 71 SK G AQP+ G L VLLHW GP GGEPWVTFS++SLTAEEVCIHIAHKVGITPPC Sbjct 17 SKADGTEAQPLVPTGCLMVLLHWPGPEGGEPWVTFSQTSLTAEEVCIHIAHKVGITPPCL 76 Query 72 NLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTE 131 NLFAL++AQA+VWLPPNHIL+ +D + LYFR+RFYFRNWHGMNP+EPAVYRCG PG E Sbjct 77 NLFALYNAQAKVWLPPNHILDTSQD--MNLYFRMRFYFRNWHGMNPQEPAVYRCGFPGAE 134 Query 132 ASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHL 191 SSD+ QG+QLLD ASFEYLFEQGKHEF+NDV SL +LS+EEEIHHFKNESLGMAFLHL Sbjct 135 TSSDRAEQGVQLLDSASFEYLFEQGKHEFMNDVVSLRDLSSEEEIHHFKNESLGMAFLHL 194 Query 192 CHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLS 251 CHLAL G+PLEE+A++ SFK+CIP SFR+HIRQH+ LTRLRL VFRRFLR F+PG LS Sbjct 195 CHLALSRGVPLEEMAREISFKNCIPHSFRQHIRQHNVLTRLRLHRVFRRFLRAFRPGHLS 254 Query 252 QQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGP 311 QQ+VMVKYLATLERLAPRFG+ER+PVCHL +LAQ E +PCYI++SG DPGPE +GP Sbjct 255 QQVVMVKYLATLERLAPRFGSERIPVCHLEVLAQPERDPCYIQNSGQTAGDPGPELPSGP 314 Query 312 PTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPRE 371 PTHEVLVTGTGGIQW P++ +E G+S NP S GKK KA KA + P+E Sbjct 315 PTHEVLVTGTGGIQWHPLQ----TQESERGNSRGNPHGSRSGKKPKAPKAGEHLTESPQE 370 Query 372 PLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSS 431 P W YFCDF+DI+HVVLKE V IH QDNKCL L L S+A ALSFV+LVDGYFRLTADSS Sbjct 371 PPWTYFCDFQDISHVVLKERRVHIHLQDNKCLLLCLCSQAEALSFVALVDGYFRLTADSS 430 Query 432 HYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRS 491 HYLCHEVAPPRLV SI++GIHGPL++PFVQAKL PEDGLYLI WSTSH +RLILTVA R+ Sbjct 431 HYLCHEVAPPRLVTSIQNGIHGPLMDPFVQAKLWPEDGLYLIQWSTSHLHRLILTVAHRN 490 Query 492 QA-PDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRC 550 A +G + LRLRKFPI QQ GAFVL+GWGRSF S+ +L ALQGC LRAGDDCF L C Sbjct 491 PAFSNGPRGLRLRKFPITQQPGAFVLDGWGRSFASLGDLRLALQGCSLRAGDDCFPLHHC 550 Query 551 CLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRV 610 CLP+P E SNL+IMRG+RA R LNLSQLSFHRV Q EITQLSHLGQGTRTNVYEG LRV Sbjct 551 CLPRPREISNLVIMRGSRAHTRPLNLSQLSFHRVHQDEITQLSHLGQGTRTNVYEGLLRV 610 Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670 G P+EGK+D+ P PG GQ+LRVVLKVLDPSHHDIALAFYETASLMSQVSH HL Sbjct 611 ---GGPDEGKVDNGCPPEPGGTSGQQLRVVLKVLDPSHHDIALAFYETASLMSQVSHMHL 667 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730 AF+HGVCVRG ENI+VTE+VEHGPLDVWLRR+RG VPM WKMVVAQQLASALSYLE+KNL Sbjct 668 AFLHGVCVRGSENIIVTEFVEHGPLDVWLRRQRGQVPMTWKMVVAQQLASALSYLEDKNL 727 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANS 790 VHGNVCGRNILLARLGL EGT+PFIKLSDPGVG GALSREERVERIPW APECL GG +S Sbjct 728 VHGNVCGRNILLARLGLEEGTNPFIKLSDPGVGQGALSREERVERIPWTAPECLSGGTSS 787 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLT 850 L TA D WGFGATLLEICFDGEAPLQ R PSEKE FY ++H+LPEPS P+LATLT QCLT Sbjct 788 LGTATDMWGFGATLLEICFDGEAPLQGRGPSEKERFYTKKHQLPEPSSPELATLTRQCLT 847 Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910 YEP QRPSFRTILRDLTRLQP NL VN DSPASDPTVFHKRYLKKIRDLGEGHFGK Sbjct 848 YEPAQRPSFRTILRDLTRLQPQNLVGTSAVNSDSPASDPTVFHKRYLKKIRDLGEGHFGK 907 Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970 VSLYCYDPTNDGTGEMVAVKALK CGPQ RSGW++EI+ILRTLYHEHI+KYKGCCEDQG Sbjct 908 VSLYCYDPTNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVKYKGCCEDQG 967 Query 971 EKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030 EKS+QLVMEYVPLGSLRDYLPRH +GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL Sbjct 968 EKSVQLVMEYVPLGSLRDYLPRHCVGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1027 Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE KFYYASDVWSFGVT Sbjct 1028 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSFGVT 1087 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 LYELLT+CDS+QSP KF ELIG QGQMTVLRLTELLERGERLPRPD+CPCE+YHLMKN Sbjct 1088 LYELLTYCDSNQSPHMKFTELIGHTQGQMTVLRLTELLERGERLPRPDRCPCEIYHLMKN 1147 Query 1151 CWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC 1187 CWETEASFRPTF+NL+PIL+T EKYQGQ PSVFSVC Sbjct 1148 CWETEASFRPTFQNLVPILQTAQEKYQGQVPSVFSVC 1184 >sp|P23458|JAK1_HUMAN Tyrosine-protein kinase JAK1 OS=Homo sapiens OX=9606 GN=JAK1 PE=1 SV=2 Length=1154 Score = 1014 bits (2623), Expect = 0.0, Method: Compositional matrix adjust. Identities = 529/1130 (47%), Positives = 724/1130 (64%), Gaps = 54/1130 (5%) Query 52 TAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRN 111 TAEE+CI A I+P C NLFAL+D ++W PN + + SL L++R+RFYF N Sbjct 56 TAEELCIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTN 115 Query 112 WHGMNPREPAVYRCGPPGTEASSDQTA--QGMQLLDPASFEYLFEQGKHEFVNDVASLWE 169 WHG N E +V+R P + ++ LLD +S EYLF QG+++ V +A + + Sbjct 116 WHGTNDNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRD 175 Query 170 LSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSAL 229 TE++ H +NE LGMA L + H A+ + L E+ K S+K IP + + IRQ + L Sbjct 176 PKTEQDGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLL 235 Query 230 TRLRLRNVFRRFLRDFQ-----PGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLA 284 TR+R+ NVF+ FL++F +S + VKYLATLE L +G E L + + Sbjct 236 TRMRINNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISS 295 Query 285 QAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSG 344 + E + D G +EV+VTG GIQW + + + S Sbjct 296 ENEMNWFHSNDGG------------NVLYYEVMVTGNLGIQW--------RHKPNVVSVE 335 Query 345 RNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLE 404 + K HK + ++ RE W F F +ITH+V+KE VSI++QDNK +E Sbjct 336 KEKNKLKRKKLENKHKK-DEEKNKIREE-WNNFSYFPEITHIVIKESVVSINKQDNKKME 393 Query 405 LSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKL 464 L L S ALSFVSLVDGYFRLTAD+ HYLC +VAPP +V +I++G HGP+ + KL Sbjct 394 LKLSSHEEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKL 453 Query 465 R---PEDGLYLIHWSTSHPYRLILTVA--QRSQAPDGMQSLRLRKFPIEQQDGAFVLEGW 519 R E+G+Y++ WS + +++TV ++S+ G Q + + F IE Q G + L G Sbjct 454 RQEGSEEGMYVLRWSCTDFDNILMTVTCFEKSEQVQGAQK-QFKNFQIEVQKGRYSLHGS 512 Query 520 GRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLII-MRGARASPRTLNLSQ 578 RSFPS+ +L + L+ +LR + F L+RCC P+P E SNL++ + A+ +SQ Sbjct 513 DRSFPSLGDLMSHLKKQILRTDNISFMLKRCCQPKPREISNLLVATKKAQEWQPVYPMSQ 572 Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 LSF R+ +K++ Q HLG+GTRT++Y G L MD +D G ++++ Sbjct 573 LSFDRILKKDLVQGEHLGRGTRTHIYSGTL------------MDYKDD--EGTSEEKKIK 618 Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V+LKVLDPSH DI+LAF+E AS+M QVSH H+ +++GVCVR ENIMV E+VE GPLD++ Sbjct 619 VILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLF 678 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + R+ + WK VA+QLASALSYLE+K+LVHGNVC +N+LLAR G+ PFIKLS Sbjct 679 MHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSECGPFIKLS 738 Query 759 DPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 DPG+ + LSR+E +ERIPW+APEC+ N LS A DKW FG TL EIC++GE PL+ + Sbjct 739 DPGIPITVLSRQECIERIPWIAPECVEDSKN-LSVAADKWSFGTTLWEICYNGEIPLKDK 797 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + EKE FY+ + R PSC +LA L ++C+ Y+P QRP FR I+RD+ +L+ N D++ Sbjct 798 TLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQN-PDIV 856 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 + + DPT F KR+LK+IRDLGEGHFGKV L YDP D TGE VAVK+LK + G Sbjct 857 SEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGG 916 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IG 996 H + K+EI+ILR LYHE+I+KYKG C + G ++L+ME++P GSL++YLP++ I Sbjct 917 NHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKIN 976 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 L Q L +A QIC+GM YL ++ Y+HRDLAARNVL++++ VKIGDFGL KA+ EYY Sbjct 977 LKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYT 1036 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 V++D DSPVFWYAPECL + KFY ASDVWSFGVTL+ELLT+CDS SP FL++IG Sbjct 1037 VKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTH 1096 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 GQMTV RL L+ G+RLP P CP EVY LM+ CWE + S R +F+NLI Sbjct 1097 GQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLI 1146 Score = 68.9 bits (167), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 66/289 (23%), Positives = 126/289 (44%), Gaps = 39/289 (13%) Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQV 665 R+R G G + ++ DP G + G++ V +K L P +A + ++ + Sbjct 877 RIRDLGEGHFGKVELCRYDP--EGDNTGEQ--VAVKSLKPESGGNHIADLKKEIEILRNL 932 Query 666 SHTHLAFVHGVCVRGPEN--IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723 H ++ G+C N ++ E++ G L +L + + + + ++ A Q+ + Sbjct 933 YHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMD 992 Query 724 YLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS-------REERVERI 776 YL ++ VH ++ RN+L+ + +K+ D G+ + +++R + Sbjct 993 YLGSRQYVHRDLAARNVLVE-------SEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPV 1045 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEI---CFDGEAP----LQSRSPSEKEHFYQR 829 W APECL + A D W FG TL E+ C +P L+ P+ + R Sbjct 1046 FWYAPECL--MQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTR 1103 Query 830 -------QHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 RLP P+CP ++ L +C ++P+ R SF+ ++ L Sbjct 1104 LVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEAL 1152 >sp|P52332|JAK1_MOUSE Tyrosine-protein kinase JAK1 OS=Mus musculus OX=10090 GN=Jak1 PE=1 SV=1 Length=1153 Score = 1013 bits (2619), Expect = 0.0, Method: Compositional matrix adjust. Identities = 529/1130 (47%), Positives = 728/1130 (64%), Gaps = 55/1130 (5%) Query 52 TAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRN 111 TAEE+CI A + I+P C NLFAL+D ++W PN I+ + SL L++R+RFYF N Sbjct 56 TAEELCIRAAQECSISPLCHNLFALYDESTKLWYAPNRIITVDDKTSLRLHYRMRFYFTN 115 Query 112 WHGMNPREPAVYRCGPPGTEASSDQ--TAQGMQLLDPASFEYLFEQGKHEFVNDVASLWE 169 WHG N E +V+R P + ++ + LLD +S EYLF QG+++ + +A + + Sbjct 116 WHGTNDNEQSVWRHSPKKQKNGYEKKRVPEATPLLDASSLEYLFAQGQYDLIKCLAPIRD 175 Query 170 LSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSAL 229 TE++ H +NE LGMA L + H A+ + L E+ K S+K IP + + IRQ + L Sbjct 176 PKTEQDGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLL 235 Query 230 TRLRLRNVFRRFLRDFQPGRLSQQMV---MVKYLATLER--LAPRFGTERVPVCHLRLLA 284 TR+R+ NVF+ FL++F + V VKYLATLE L +G E L + + Sbjct 236 TRMRINNVFKDFLKEFNNKTICDSSVHDLKVKYLATLETSTLTKHYGAEIFETSMLLISS 295 Query 285 QAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSG 344 + E C+ DSG +EV+VTG GIQW ++ N + Sbjct 296 ENELSRCHSNDSGNV-------------LYEVMVTGNLGIQW---RQKPNVVPVEKEKNK 339 Query 345 RNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLE 404 + + K K ++ RE W F F +ITH+V+KE VSI++QDNK +E Sbjct 340 LKRKKLEYNKHKK-----DDERNKLREE-WNNFSYFPEITHIVIKESVVSINKQDNKNME 393 Query 405 LSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKL 464 L L SR ALSFVSLVDGYFRLTAD+ HYLC +VAPP +V +I++G HGP+ + KL Sbjct 394 LKLSSREEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKL 453 Query 465 R---PEDGLYLIHWSTSHPYRLILTVA--QRSQAPDGMQSLRLRKFPIEQQDGAFVLEGW 519 R E+G+Y++ WS + +++TV ++S+ G + + + F IE Q G + L G Sbjct 454 RQEGSEEGMYVLRWSCTDFDNILMTVTCFEKSEVLGGQK--QFKNFQIEVQKGRYSLHGS 511 Query 520 GRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLII-MRGARASPRTLNLSQ 578 FPS+R+L L+ +LR + F L+RCC P+P E SNL++ + A+ ++SQ Sbjct 512 MDHFPSLRDLMNHLKKQILRTDNISFVLKRCCQPKPREISNLLVATKKAQEWQPVYSMSQ 571 Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 LSF R+ +K+I Q HLG+GTRT++Y G L +D +D G ++++ Sbjct 572 LSFDRILKKDIIQGEHLGRGTRTHIYSGTL------------LDYKDE--EGIAEEKKIK 617 Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V+LKVLDPSH DI+LAF+E AS+M QVSH H+ +++GVCVR ENIMV E+VE GPLD++ Sbjct 618 VILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLF 677 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + R+ + WK VA+QLASALSYLE+K+LVHGNVC +N+LLAR G+ PFIKLS Sbjct 678 MHRKSDALTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSDIGPFIKLS 737 Query 759 DPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 DPG+ + L+R+E +ERIPW+APEC+ N LS A DKW FG TL EIC++GE PL+ + Sbjct 738 DPGIPVSVLTRQECIERIPWIAPECVEDSKN-LSVAADKWSFGTTLWEICYNGEIPLKDK 796 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + EKE FY+ + R PSC +LA L ++C+ Y+P QRP FR I+RD+ +L+ N D++ Sbjct 797 TLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQN-PDIV 855 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 + + DPT F KR+LK+IRDLGEGHFGKV L YDP D TGE VAVK+LK + G Sbjct 856 SEKQPTTEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGG 915 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IG 996 H + K+EI+ILR LYHE+I+KYKG C + G ++L+ME++P GSL++YLP++ I Sbjct 916 NHIADLKKEIEILRNLYHENIVKYKGICMEDGGNGIKLIMEFLPSGSLKEYLPKNKNKIN 975 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 L Q L +A QIC+GM YL ++ Y+HRDLAARNVL++++ VKIGDFGL KA+ EYY Sbjct 976 LKQQLKYAIQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYT 1035 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 V++D DSPVFWYAPECL + KFY ASDVWSFGVTL+ELLT+CDS SP FL++IG Sbjct 1036 VKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDFSPMALFLKMIGPTH 1095 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 GQMTV RL + L+ G+RLP P CP EVY LM+ CWE + S R TF+NLI Sbjct 1096 GQMTVTRLVKTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTTFQNLI 1145 >sp|O12990|JAK1_DANRE Tyrosine-protein kinase JAK1 OS=Danio rerio OX=7955 GN=jak1 PE=1 SV=1 Length=1153 Score = 990 bits (2560), Expect = 0.0, Method: Compositional matrix adjust. Identities = 535/1162 (46%), Positives = 730/1162 (63%), Gaps = 65/1162 (6%) Query 23 AAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQ 82 AM GL++ + A E F ++ TAE++C+ A + I+P C NLFAL++ Sbjct 29 TAMKGLEIHFYLADTHQLE----FFKACYTAEDLCVEAAKRCRISPLCHNLFALYEESQD 84 Query 83 VWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYR--CGPPGTEASSDQTAQG 140 +W PNH+ ++ + S+ L++R+RFYF NWHG + E V+R + +S +T +G Sbjct 85 LWYAPNHVFKVTDETSIKLHYRMRFYFTNWHGTSEIESPVWRHTLSKQKSVLNSQKTTEG 144 Query 141 MQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGI 200 LLD AS +YLF QG+++F+ ++ + T+EE H +NE LGMA L + H A + + Sbjct 145 TPLLDAASLDYLFAQGQYDFLRGLSPVRPTQTDEEHHEIENECLGMAVLAITHHAKSNNL 204 Query 201 PLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMV----- 255 PL +TS+K IP S R I+Q + LTR+R+ NVF+ FL +F + + Sbjct 205 PLSGAGAETSYKRFIPDSLNRTIKQRNFLTRIRISNVFKNFLNEFNSKTIQDSNIGLYDL 264 Query 256 MVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHE 315 VKYL+TLE L G E +L++ ++EG P A P ++ G +E Sbjct 265 KVKYLSTLETLTQGVGREIFKPKNLKVTGESEGSP--------AQMLPLGDNGMG---YE 313 Query 316 VLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVG--QPADRPREPL 373 V V GT GI W P + K K+ K G Q D+ ++ Sbjct 314 VQVYGTTGISW---------------RRKPAPNQLILKDKPKSKKIKGDKQWNDKKKDSG 358 Query 374 WAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHY 433 W F DF +ITH+V+K+ CV+I+RQDNK +EL L R AALSF +LVDGYFRLT D+ HY Sbjct 359 WTLFSDFHEITHIVIKDCCVTIYRQDNKTMELDLFYRDAALSFAALVDGYFRLTVDAHHY 418 Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWS-TSHPYRLILTVAQ 489 LC +VAP +V ++ +G HGP+ + KLR E +G Y++ WS T + + ++ V Sbjct 419 LCTDVAPSSVVQNLENGCHGPICTEYAIHKLRQEGNEEGTYVLRWSCTEYNFIIMTVVCI 478 Query 490 RSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRR 549 + + + F IE + L G P+++EL LQG LLR + F LRR Sbjct 479 ELDLCESRPVPQYKNFQIETSPQGYRLYGTDTFRPTLKELLEHLQGQLLRTDNLRFQLRR 538 Query 550 CCLPQPGETSNLIIMRGAR--ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 CC PQP E SNL++M R + +SQLSF R+ ++EI Q HLG+GTRTN+Y G Sbjct 539 CCPPQPREISNLLVMTTDREPVPQKKTQVSQLSFDRILKEEIVQGEHLGRGTRTNIYAGI 598 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667 L+ K DDED L QE++VVLKVL H DI+LAF+ETAS+M Q+SH Sbjct 599 LK---------PKSDDEDDL---GGYSQEVKVVLKVLGSGHRDISLAFFETASMMRQISH 646 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 H A ++GVCVR ENIMV E+V++GPLD+++RR+ + AWK VA+QLASALSYLE+ Sbjct 647 KHTALLYGVCVRHQENIMVEEFVQYGPLDLFMRRQTTPLSTAWKFQVAKQLASALSYLED 706 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGG 787 K +VHG VC +NIL+AR GL PFIKLSDPG+ + LSREE V+RIPW+APEC+ Sbjct 707 KKMVHGYVCSKNILVARDGLDGEGGPFIKLSDPGIPITVLSREECVDRIPWIAPECVKDT 766 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ 847 AN L+ A DKW FG TL EIC++GE PL+ + SEKE FY Q +L P C +LA L + Sbjct 767 AN-LTIAADKWSFGTTLWEICYNGEIPLKDKKLSEKERFYAAQCQLATPDCDELAKLMTH 825 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS-DPTVFHKRYLKKIRDLGEG 906 C+TY+P QR FR I+RD+ ++ N + + P DPTVF KR+LKKIRDLGEG Sbjct 826 CMTYDPRQRLFFRAIVRDIVMVEKQNPS----IQPVPMLEVDPTVFEKRFLKKIRDLGEG 881 Query 907 HFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC 966 HFGKV L YDP D TGE+VAVK+LK + + + +EI ILR LYHE+I+KYKG C Sbjct 882 HFGKVELCRYDPRGDRTGELVAVKSLKPENREEQSNNLWREIHILRELYHENIVKYKGIC 941 Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDL 1024 ++G +S++L+ME++P GSL++YLPR+ I L L ++ QIC+GM YL +++YIHRDL Sbjct 942 NEEGGRSIKLIMEFLPAGSLKEYLPRNKAHINLKTLHNYSVQICQGMDYLGSRNYIHRDL 1001 Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084 AARNVL++N+ VKIGDFGL K++ + YY V++D DSPVFWYAPECL KFY ASDV Sbjct 1002 AARNVLVENEGTVKIGDFGLTKSIKDNEGYYTVKDDLDSPVFWYAPECLIHCKFYRASDV 1061 Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144 WSFGVT+YELLT+CD+S SP + FL+LIG GQMTV RL ++LE G+RLPRPD C ++ Sbjct 1062 WSFGVTMYELLTYCDASCSPMSVFLKLIGPTHGQMTVTRLVKVLEEGKRLPRPDDCSEQL 1121 Query 1145 YHLMKNCWETEASFRPTFENLI 1166 Y+LM+ CWE R F++LI Sbjct 1122 YNLMRRCWEATPEKRIDFKSLI 1143 >sp|Q09178|JAK1_CYPCA Tyrosine-protein kinase JAK1 OS=Cyprinus carpio OX=7962 GN=jak1 PE=2 SV=1 Length=1156 Score = 920 bits (2379), Expect = 0.0, Method: Compositional matrix adjust. Identities = 520/1169 (44%), Positives = 708/1169 (61%), Gaps = 74/1169 (6%) Query 22 MAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCF-NLFALFDAQ 80 + M GL++ H+ P + + + + TAE++C+ + + C NLFAL + Sbjct 28 LTVMKGLEI--HFYLPDTHQ--LEYFKDCHTAEDLCVEGCQEDATSHLCADNLFALSEES 83 Query 81 AQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCG--PPGTEASSDQTA 138 +W PNH +I + S+ L++R+RFYF NWH E V+R + S + Sbjct 84 QDLWYAPNHAFKITEETSIKLHYRMRFYFTNWHAPVRTESPVWRHSLFKHKGVSVSPKGP 143 Query 139 QGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRH 198 +G LLD AS EYLF QG+++F+ +A + E E H +NE LGMA L + H A + Sbjct 144 EGTPLLDAASLEYLFAQGQYDFLRGLAPVRAPQNEAEKHEIENECLGMAVLAITHHAKSN 203 Query 199 GIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDF-----QPGRLSQQ 253 +PL V +TS+K IP S R I+Q + NVF+ FL +F Q ++ Sbjct 204 DLPLSGVGAETSYKRFIPDSLNRTIKQRNFSHVYVYNNVFKNFLNEFNSKTIQDSNITLY 263 Query 254 MVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPT 313 + VKYL+TLE L G E + L++ +++G P A T P + G Sbjct 264 DLKVKYLSTLETLTQGLGRETIEPKILKVSGESDGSP--------ALTLPSGDDGLG--- 312 Query 314 HEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLF-------GKKAKAHKAVGQPA 366 +EV V+GT GI W R P ++ KK KA K + Sbjct 313 YEVQVSGTTGISW-----------------RRKPVPNILIVKDKTKSKKNKADKQSKKEM 355 Query 367 DRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRL 426 + R+ + F DF +ITH+V+KE C +I+ QDNK +EL L R AALSF +LVDGYFRL Sbjct 356 TK-RKTVMTIFSDFFEITHIVIKESCATIYSQDNKTMELDLFYRDAALSFAALVDGYFRL 414 Query 427 TADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWS-TSHPYR 482 T D+ HYLC EVAP +V ++ +G HGP+ + KLR E +G Y++ WS T + Y Sbjct 415 TVDAHHYLCTEVAPSSVVQNLENGCHGPICTEYAIHKLRQEGNEEGTYVLRWSCTDYNYI 474 Query 483 LILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGD 542 ++ V + + + F IE + L G P+++EL LQG LR + Sbjct 475 IMTVVCIEMDLCESRPVPQYKNFQIETSPQGYRLYGTDTFRPTLKELLEHLQGQNLRTEN 534 Query 543 DCFSLRRCCLPQPGETSNLIIMRGARA--SPRTLNLSQLSFHRVDQKEITQLSHLGQGTR 600 F L QP + SNL++M R S R +SQLSFHR+ ++EI Q HLG+GTR Sbjct 535 LRFQPVLVGLGQPRKISNLLVMTRDREPDSQRQPQVSQLSFHRILKEEIVQGEHLGRGTR 594 Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660 TN+Y G L+++ D + G QE++V+LKVL H DI+LAF+ETAS Sbjct 595 TNIYSGVLKLKSEDDDDMGGY------------SQEVKVILKVLGSGHRDISLAFFETAS 642 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 +M Q+SH H+A ++GVCVR ENIMV E+V++GPLD+++RR+ + AWK VA+QLA Sbjct 643 MMRQISHKHIALLYGVCVRHQENIMVEEFVQYGPLDLFMRRQSIPLSTAWKFQVAKQLAG 702 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780 ALSYLE+K LVHGNVC +NIL+AR GL PFIKLSDPG+ + LSREE V+R+PW+A Sbjct 703 ALSYLEDKKLVHGNVCSKNILVARDGLDGEGGPFIKLSDPGIPITVLSREECVDRLPWIA 762 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840 PEC+ AN LS A DKWGFG TL EIC++GE PL+ + +EKE FY Q +L P C + Sbjct 763 PECVQDTAN-LSIAADKWGFGTTLWEICYNGEIPLKDKKLTEKERFYAAQCQLASPDCEE 821 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS-DPTVFHKRYLKK 899 LA L + C+TY+P QR FR I+RD+ ++ N + + P DPTVF KR+LKK Sbjct 822 LAKLMTHCMTYDPRQRLFFRAIVRDIDMVEKQNPS----IQPVPMLEVDPTVFEKRFLKK 877 Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 IRDLGEGHFGKV L YDP D TGE+VAVK+LK + + S +EI ILR LYHE+I Sbjct 878 IRDLGEGHFGKVELCRYDPRGDRTGELVAVKSLKPENREEQSSNLWREIHILRELYHENI 937 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQ 1017 +KYKG ++G +S++L+ME++P GSL++YLPR+ I L LL +A QIC+GM L ++ Sbjct 938 VKYKGIWHEEGGRSIKLIMEFLPAGSLKEYLPRNKAHIDLKTLLNYAVQICQGMDLLASR 997 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +YIHRDLAARNVL++N+ VKIGDFGL K++ + YY V++D DSPVFWYAPECL K Sbjct 998 NYIHRDLAARNVLVENENTVKIGDFGLTKSIKDNEGYYTVKDDLDSPVFWYAPECLIHCK 1057 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 FY ASDVWSFGVT+YELLT+CD S SP + FL +IG GQMTV RL ++LE G+RLP+P Sbjct 1058 FYRASDVWSFGVTMYELLTYCDISCSPMSVFLTMIGPTHGQMTVTRLVKVLEEGKRLPKP 1117 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 D C +Y LM+ CWE R F+ LI Sbjct 1118 DGCSDRLYCLMRRCWEATPEKRIDFKGLI 1146 >sp|Q75R65|JAK2_CHICK Tyrosine-protein kinase JAK2 OS=Gallus gallus OX=9031 GN=JAK2 PE=2 SV=1 Length=1129 Score = 781 bits (2017), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/1204 (38%), Positives = 649/1204 (54%), Gaps = 138/1204 (11%) Query 15 VGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLF 74 +G+ + P L+V L+++ G ++ F AEE+CI GI P N+F Sbjct 24 LGNTSAPKQTEPLLQVYLYYSPGKTGGDYLQFPAGEYVAEEICIVACKACGIMPVYHNMF 83 Query 75 ALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASS 134 AL +VW PPNHI + L L +RIRFYF +W+ Y G+E+ Sbjct 84 ALMSETERVWYPPNHIFHVDEATRLKLLYRIRFYFPHWYCNGTSRACRYGI-IRGSESP- 141 Query 135 DQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHL 194 +LD YLF Q + +F++ + H + E LGMA L + + Sbjct 142 --------VLDDLVMSYLFAQWRKDFLDGWIQM------PVTHETQEECLGMAVLDMMRV 187 Query 195 ALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQM 254 A V S+K +P+ R I+++ LTR R+R FR+F++ F + + + Sbjct 188 AKEKDQTPLAVYNSVSYKMFLPKCVRAKIQEYHILTRKRIRYRFRKFIQQFGQCKATARN 247 Query 255 VMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTH 314 + +KYL LE L F +E V +PG + + Sbjct 248 LKLKYLINLETLQSAFYSEVFEV-----------------------KEPGGDPSGEESFA 284 Query 315 EVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLW 374 +++TG GGIQ S G+ ++ Sbjct 285 TIVITGNGGIQC---------------SRGKLKNCETLAEQD-----------------L 312 Query 375 AYFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFR 425 +CDF DI V +K+ V+IH+QD+K LE S ALSFVSL+DGY+R Sbjct 313 QTYCDFPDIIDVSIKQASQEGSSERRIVTIHKQDSKNLEAEFQSLREALSFVSLIDGYYR 372 Query 426 LTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYR 482 LTAD+ HYLC EVAPP ++ +I+ HGP+ F KL+ + G Y++ S + Sbjct 373 LTADAHHYLCKEVAPPSVLENIQSNCHGPIFMDFAINKLKKAGNQTGFYVLRCSPKDFKK 432 Query 483 LILTVA-QRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAG 541 LT A +R A D L + ++G + L G RSF ++++L Q +R+ Sbjct 433 YFLTFAIERENATDYKHCLITK-----NENGEYNLSGTKRSFGNLKDLLTCYQTETVRSD 487 Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASP-------RTLNLSQLSFHRVDQKEITQLSH 594 F +CC P+P + SNL++ R S + N+SQ+ FH++ +++ Sbjct 488 SIIFQFIKCCPPKPKDKSNLLVFRSNSVSDVPSSPTLQRHNVSQMVFHKIRNEDLIFEES 547 Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ--ELRVVLKVLDPSHHDIA 652 LGQGT T +++G + G D GQ + V+LKVLD H + + Sbjct 548 LGQGTFTKIFKGIRKEVG-------------------DYGQLHQTEVLLKVLDKVHRNYS 588 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 +F+E AS+MSQ+S+ HL +GVCV G ENI+V EYV+ G LD +L++ + + + WK+ Sbjct 589 ESFFEAASMMSQLSYKHLVLNYGVCVCGEENILVQEYVKFGSLDTYLKKNKNVINILWKL 648 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARL-GLAEGTSPFIKLSDPGVGLGALSREE 771 VA+QLA A+ +LE+K LVHGNVC +NILL R G PFIKLSDPG+ + L R+ Sbjct 649 EVAKQLALAMHFLEDKGLVHGNVCAKNILLIREEDRKSGNLPFIKLSDPGISITVLPRDI 708 Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 +ERIPW+ PEC+ LS A DKW FG TL EIC G+ PL + S K FY+ +H Sbjct 709 LLERIPWVPPECIEN-PRQLSLATDKWSFGTTLWEICSGGDKPLSALDSSRKLQFYEDRH 767 Query 832 RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA----- 886 +LP P+ +LA L + C+ YEP RPSFR I+RDL L + ++LT N P Sbjct 768 QLPAPNWTELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDY-ELLTENDMLPNIRTGA 826 Query 887 ---------SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L+ Sbjct 827 LGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST- 885 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL 997 +H +++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H L Sbjct 886 EEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERL 945 Query 998 --AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 +LLL+A QIC+GM YL + Y+HRDLA RN+L++N+ VKIGDFGL K +P+ EYY Sbjct 946 DHKKLLLYASQICKGMEYLGTKRYVHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYY 1005 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI- 1114 +V+E G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG Sbjct 1006 KVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGND 1065 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 QGQM V L ELL+ RLPRPD CP E+Y +MK CW + RPTF +L + + + Sbjct 1066 KQGQMIVFHLIELLKNNGRLPRPDGCPDEIYAIMKECWNNNVAQRPTFRDLAQRVDQIRD 1125 Query 1175 KYQG 1178 G Sbjct 1126 NMGG 1129 >sp|Q62689|JAK2_RAT Tyrosine-protein kinase JAK2 OS=Rattus norvegicus OX=10116 GN=Jak2 PE=1 SV=1 Length=1132 Score = 765 bits (1976), Expect = 0.0, Method: Compositional matrix adjust. Identities = 451/1180 (38%), Positives = 641/1180 (54%), Gaps = 148/1180 (13%) Query 31 LLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHI 90 L H G G+ ++ F AEE+C+ + GITP N+FAL ++W PPNH+ Sbjct 43 LYHSLGQAEGD-YLKFPNGEYVAEEICVAASKACGITPVYHNMFALMSETERIWYPPNHV 101 Query 91 LEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPP-GTEASSDQTAQGMQLLDPASF 149 I + +RIRFYF +W+ YR G G EA LLD Sbjct 102 FHIDESTRHNILYRIRFYFPHWYCSGSNR--TYRYGVSRGAEAP---------LLDDFVM 150 Query 150 EYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKT 209 YLF Q +H+FV+ + H + E LGMA L + +A V Sbjct 151 SYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLDMMRIAKEKDQTPLAVYNSI 204 Query 210 SFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPR 269 S+K +P+ R I+ + LTR R+R FRRF++ F + + + + +KYL LE L Sbjct 205 SYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNLKLKYLINLETLQSA 264 Query 270 FGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEV----LVTGTGGIQ 325 F TE+ V ESA GP E+ ++TG GGIQ Sbjct 265 FYTEQFEV---------------------------KESARGPSGEEIFATIIITGNGGIQ 297 Query 326 WWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITH 385 W S G++ ++ ++ +CDF DI Sbjct 298 W---------------SRGKHKESETLTEQD-----------------LQLYCDFPDIID 325 Query 386 VVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCH 436 V +K+ V++H+QD K LE+ L S ALSFVSL+DGY+RLTAD+ HYLC Sbjct 326 VSIKQANQECSTESRVVTVHKQDGKVLEIELSSLKEALSFVSLIDGYYRLTADAHHYLCK 385 Query 437 EVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQA 493 EVAPP ++ +I HGP+ F +KL+ + GLY++ S + LT A + Sbjct 386 EVAPPAVLENIHSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVEREN 445 Query 494 PDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLP 553 + + K ++G + L G R+F S+++L Q +R+ F +CC P Sbjct 446 VIEYKHCLITK----NENGEYNLSGTKRNFSSLKDLLNCYQMETVRSDSIIFQFTKCCPP 501 Query 554 QPGETSNLIIMRGARASPRTL--------NLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605 +P + SNL++ R S L N++Q+ FH++ +++ LGQGT T +++ Sbjct 502 KPKDKSNLLVFRTNGVSDVQLSPTLQRHNNVNQMVFHKIRNEDLIFNESLGQGTFTKIFK 561 Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ--ELRVVLKVLDPSHHDIALAFYETASLMS 663 G R G D GQ E V+LKVLD +H + + +F+E AS+MS Sbjct 562 GVRREVG-------------------DYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS 602 Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723 Q+SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+ VA+QLA A+ Sbjct 603 QLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLGVAKQLAWAMH 662 Query 724 YLENKNLVHGNVCGRNILLARL-GLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPE 782 +LE K+L+HGNVC +NILL R G PFIKLSDPG+ + L ++ ERIPW+ PE Sbjct 663 FLEEKSLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE 722 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLA 842 C+ N L+ A DKW FG TL EIC G+ PL + K FY+ +H+LP P +LA Sbjct 723 CIENPKN-LTLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDKHQLPAPKWTELA 781 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA--------------SD 888 L + C+ YEP RP+FR ++RDL L + ++LT N P D Sbjct 782 NLINTCMDYEPDFRPAFRAVIRDLNSLFTPDY-ELLTENDMLPNMRIGALGFSGAFEDRD 840 Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 PT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L+ +H +++EI Sbjct 841 PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST-EEHLRDFEREI 899 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006 +IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I +LL + Q Sbjct 900 EILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQ 959 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 IC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V+E G+SP+F Sbjct 960 ICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIF 1019 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQGQMTVLRLT 1125 WYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG QGQM V L Sbjct 1020 WYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDKQGQMIVFHLI 1079 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 ELL+ RLPRP+ CP E+Y +M CW + RP+F +L Sbjct 1080 ELLKNNGRLPRPEGCPDEIYVIMTECWNNNVNQRPSFRDL 1119 Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 92/361 (25%), Positives = 163/361 (45%), Gaps = 56/361 (16%) Query 837 SCPQLATLTSQCLTYEPTQ----RPSFRTILRDLTRLQPHNLADVLTVNPD---SPASDP 889 +C Q+ T+ S + ++ T+ +P ++ +L + + ++DV ++P + Sbjct 479 NCYQMETVRSDSIIFQFTKCCPPKPKDKS---NLLVFRTNGVSDV-QLSPTLQRHNNVNQ 534 Query 890 TVFHKRYLKKI---RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS---G 943 VFHK + + LG+G F K+ D G++ + L HR+ Sbjct 535 MVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGD-YGQLHETEVLLKVLDKAHRNYSES 593 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLL 1001 + + ++ L H+H++ G C GE+++ LV E+V GSL YL ++ SI + L Sbjct 594 FFEAASMMSQLSHKHLVLNYGVCV-CGEENI-LVQEFVKFGSLDTYLKKNKNSINILWKL 651 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL--DNDR------LVKIGDFGLAKAV-PEGH 1052 A+Q+ M +L + IH ++ A+N+LL + DR +K+ D G++ V P+ Sbjct 652 GVAKQLAWAMHFLEEKSLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDI 711 Query 1053 EYYRVREDGDSPVFWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111 R+ W PEC++ K A+D WSFG TL+E+ C P + Sbjct 712 LQERIP--------WVPPECIENPKNLTLATDKWSFGTTLWEI---CSGGDKPLSA---- 756 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + R + E +LP P E+ +L+ C + E FRP F +I L + Sbjct 757 -------LDSQRKLQFYEDKHQLPAPKWT--ELANLINTCMDYEPDFRPAFRAVIRDLNS 807 Query 1172 V 1172 + Sbjct 808 L 808 >sp|Q62120|JAK2_MOUSE Tyrosine-protein kinase JAK2 OS=Mus musculus OX=10090 GN=Jak2 PE=1 SV=3 Length=1132 Score = 764 bits (1973), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/1180 (38%), Positives = 643/1180 (54%), Gaps = 148/1180 (13%) Query 31 LLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHI 90 L H G GE ++ F AEE+C+ + GITP N+FAL ++W PPNH+ Sbjct 43 LYHSLGQAEGE-YLKFPSGEYVAEEICVAASKACGITPVYHNMFALMSETERIWYPPNHV 101 Query 91 LEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPP-GTEASSDQTAQGMQLLDPASF 149 I + +RIRFYF +W+ YR G G EA LLD Sbjct 102 FHIDESTRHDILYRIRFYFPHWYCSGSSR--TYRYGVSRGAEAP---------LLDDFVM 150 Query 150 EYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKT 209 YLF Q +H+FV+ + H + E LGMA L + +A V Sbjct 151 SYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLDMMRIAKEKDQTPLAVYNSV 204 Query 210 SFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPR 269 S+K +P+ R I+ + LTR R+R FRRF++ F + + + + +KYL LE L Sbjct 205 SYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNLKLKYLINLETLQSA 264 Query 270 FGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEV----LVTGTGGIQ 325 F TE+ V ESA GP E+ ++TG GGIQ Sbjct 265 FYTEQFEV---------------------------KESARGPSGEEIFATIIITGNGGIQ 297 Query 326 WWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITH 385 W S G++ ++ ++ +CDF DI Sbjct 298 W---------------SRGKHKESETLTEQDVQ-----------------LYCDFPDIID 325 Query 386 VVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCH 436 V +K+ V++H+QD K LE+ L S ALSFVSL+DGY+RLTAD+ HYLC Sbjct 326 VSIKQANQECSNESRIVTVHKQDGKVLEIELSSLKEALSFVSLIDGYYRLTADAHHYLCK 385 Query 437 EVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQA 493 EVAPP ++ +I HGP+ F +KL+ + GLY++ S + LT A + Sbjct 386 EVAPPAVLENIHSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVEREN 445 Query 494 PDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLP 553 + + K ++G + L G R+F ++++L Q +R+ F +CC P Sbjct 446 VIEYKHCLITK----NENGEYNLSGTKRNFSNLKDLLNCYQMETVRSDSIIFQFTKCCPP 501 Query 554 QPGETSNLIIMR-----GARASP---RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605 +P + SNL++ R + SP R N++Q+ FH++ +++ LGQGT T +++ Sbjct 502 KPKDKSNLLVFRTNGISDVQISPTLQRHNNVNQMVFHKIRNEDLIFNESLGQGTFTKIFK 561 Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ--ELRVVLKVLDPSHHDIALAFYETASLMS 663 G R G D GQ + V+LKVLD +H + + +F+E AS+MS Sbjct 562 GVRREVG-------------------DYGQLHKTEVLLKVLDKAHRNYSESFFEAASMMS 602 Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723 Q+SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+ VA+QLA A+ Sbjct 603 QLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLGVAKQLAWAMH 662 Query 724 YLENKNLVHGNVCGRNILLARL-GLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPE 782 +LE K+L+HGNVC +NILL R G PFIKLSDPG+ + L ++ ERIPW+ PE Sbjct 663 FLEEKSLIHGNVCAKNILLIREEDRRTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE 722 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLA 842 C+ N L+ A DKW FG TL EIC G+ PL + K FY+ +H+LP P +LA Sbjct 723 CIENPKN-LNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDKHQLPAPKWTELA 781 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA--------------SD 888 L + C+ YEP RP+FR ++RDL L + ++LT N P D Sbjct 782 NLINNCMDYEPDFRPAFRAVIRDLNSLFTPDY-ELLTENDMLPNMRIGALGFSGAFEDRD 840 Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 PT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L+ +H +++EI Sbjct 841 PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST-EEHLRDFEREI 899 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006 +IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I +LL + Q Sbjct 900 EILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQ 959 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 IC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V+E G+SP+F Sbjct 960 ICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIF 1019 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQGQMTVLRLT 1125 WYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG QGQM V L Sbjct 1020 WYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDKQGQMIVFHLI 1079 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 ELL+ RLPRP+ CP E+Y +M CW S RP+F +L Sbjct 1080 ELLKSNGRLPRPEGCPDEIYVIMTECWNNNVSQRPSFRDL 1119 Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 93/361 (26%), Positives = 164/361 (45%), Gaps = 56/361 (16%) Query 837 SCPQLATLTSQCLTYEPTQ----RPSFRTILRDLTRLQPHNLADVLTVNPD---SPASDP 889 +C Q+ T+ S + ++ T+ +P ++ +L + + ++DV ++P + Sbjct 479 NCYQMETVRSDSIIFQFTKCCPPKPKDKS---NLLVFRTNGISDV-QISPTLQRHNNVNQ 534 Query 890 TVFHKRYLKKI---RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS---G 943 VFHK + + LG+G F K+ D G++ + L HR+ Sbjct 535 MVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGD-YGQLHKTEVLLKVLDKAHRNYSES 593 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLL 1001 + + ++ L H+H++ G C GE+++ LV E+V GSL YL ++ SI + L Sbjct 594 FFEAASMMSQLSHKHLVLNYGVCV-CGEENI-LVQEFVKFGSLDTYLKKNKNSINILWKL 651 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL--DNDR------LVKIGDFGLAKAV-PEGH 1052 A+Q+ M +L + IH ++ A+N+LL + DR +K+ D G++ V P+ Sbjct 652 GVAKQLAWAMHFLEEKSLIHGNVCAKNILLIREEDRRTGNPPFIKLSDPGISITVLPKDI 711 Query 1053 EYYRVREDGDSPVFWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111 R+ W PEC++ K A+D WSFG TL+E+ C P + Sbjct 712 LQERIP--------WVPPECIENPKNLNLATDKWSFGTTLWEI---CSGGDKPLSA---- 756 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + R + E +LP P E+ +L+ NC + E FRP F +I L + Sbjct 757 -------LDSQRKLQFYEDKHQLPAPKWT--ELANLINNCMDYEPDFRPAFRAVIRDLNS 807 Query 1172 V 1172 + Sbjct 808 L 808 >sp|Q5RB23|JAK2_PONAB Tyrosine-protein kinase JAK2 OS=Pongo abelii OX=9601 GN=JAK2 PE=2 SV=1 Length=1132 Score = 759 bits (1960), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/1208 (37%), Positives = 654/1208 (54%), Gaps = 144/1208 (12%) Query 15 VGDGAQPMAAMGGLKVLLHWAGPGGGEP-WVTFSESSLTAEEVCIHIAHKVGITPPCFNL 73 + A M + + ++ + G E ++TF AEE+CI + GITP N+ Sbjct 25 ISGNANSMKQIDPVLLVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNM 84 Query 74 FALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWH--GMNPREPAVYRCGPP-GT 130 FAL ++W PPNH+ I + +RIRFYF W+ G N YR G G Sbjct 85 FALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPRWYCSGSN----RAYRHGISRGA 140 Query 131 EASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLH 190 EA LLD YLF Q +H+FV+ + H + E LGMA L Sbjct 141 EAP---------LLDDFVMSYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLD 185 Query 191 LCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRL 250 + +A + + S+K +P+ R I+ + LTR R+R FRRF++ F + Sbjct 186 MMRIAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKA 245 Query 251 SQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAG 310 + + + +KYL LE L F TE+ V ++ G P+ G E A Sbjct 246 TARNLKLKYLINLETLQSAFYTEKFEV----------------KEPGSGPS--GEEIFAT 287 Query 311 PPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPR 370 +++TG GGIQW S G++ ++ ++ Sbjct 288 -----IIITGNGGIQW---------------SRGKHKESETLTEQD-------------- 313 Query 371 EPLWAYFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVD 421 +CDF +I V +K+ V+IH+QD K LE+ L S ALSFVSL+D Sbjct 314 ---LQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREALSFVSLID 370 Query 422 GYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTS 478 GY+RLTAD+ HYLC EVAPP ++ +I+ HGP+ F +KL+ + GLY++ S Sbjct 371 GYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPK 430 Query 479 HPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLL 538 + LT A + + + K ++ + L G ++F S+++L Q + Sbjct 431 DFNKYFLTFAVERENVIEYKHCLITK----NENEEYNLSGTKKNFSSLKDLLNCYQMETV 486 Query 539 RAGDDCFSLRRCCLPQPGETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEIT 590 R+ + F +CC P+P + SNL++ R S R +++Q+ FH++ +++ Sbjct 487 RSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLI 546 Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ--ELRVVLKVLDPSH 648 LGQGT T +++G R G D GQ E V+LKVLD +H Sbjct 547 FNESLGQGTFTKIFKGVRREVG-------------------DYGQLHETEVLLKVLDKAH 587 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 + + +F+E AS+MS++SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + Sbjct 588 RNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINI 647 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL-GLAEGTSPFIKLSDPGVGLGAL 767 WK+ VA+QLA A+ +LE L+HGNVC +NILL R G PFIKLSDPG+ + L Sbjct 648 LWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVL 707 Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 ++ ERIPW+ PEC+ N L+ A DKW FG TL EIC G+ PL + K FY Sbjct 708 PKDILQERIPWVPPECIENPKN-LNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFY 766 Query 828 QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA- 886 + +H+LP P +LA L + C+ YEP RPSFR I+RDL L + ++LT N P Sbjct 767 EDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDY-ELLTENDMLPNM 825 Query 887 -------------SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933 DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L+ Sbjct 826 RIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQ 885 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993 +H +++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H Sbjct 886 HST-EEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKH 944 Query 994 S--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 I +LL + QIC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ Sbjct 945 KERIDHKKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQD 1004 Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111 EYY+V+E G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ + Sbjct 1005 KEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRM 1064 Query 1112 IGI-AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 IG QGQM V L ELL+ RLPRPD CP E+Y +M CW + RP+F +L + Sbjct 1065 IGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVD 1124 Query 1171 TVHEKYQG 1178 + + G Sbjct 1125 QIRDNMAG 1132 >sp|O60674|JAK2_HUMAN Tyrosine-protein kinase JAK2 OS=Homo sapiens OX=9606 GN=JAK2 PE=1 SV=2 Length=1132 Score = 759 bits (1960), Expect = 0.0, Method: Compositional matrix adjust. Identities = 451/1194 (38%), Positives = 650/1194 (54%), Gaps = 143/1194 (12%) Query 28 LKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPP 87 L+V L+ + ++TF AEE+CI + GITP N+FAL ++W PP Sbjct 39 LQVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNMFALMSETERIWYPP 98 Query 88 NHILEIPRDASLMLYFRIRFYFRNWH--GMNPREPAVYRCGPP-GTEASSDQTAQGMQLL 144 NH+ I + +RIRFYF W+ G N YR G G EA LL Sbjct 99 NHVFHIDESTRHNVLYRIRFYFPRWYCSGSN----RAYRHGISRGAEAP---------LL 145 Query 145 DPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEE 204 D YLF Q +H+FV+ + H + E LGMA L + +A + Sbjct 146 DDFVMSYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLDMMRIAKENDQTPLA 199 Query 205 VAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLE 264 + S+K +P+ R I+ + LTR R+R FRRF++ F + + + + +KYL LE Sbjct 200 IYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNLKLKYLINLE 259 Query 265 RLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGI 324 L F TE+ V ++ G P+ G E A +++TG GGI Sbjct 260 TLQSAFYTEKFEV----------------KEPGSGPS--GEEIFAT-----IIITGNGGI 296 Query 325 QWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDIT 384 QW S G++ ++ ++ +CDF +I Sbjct 297 QW---------------SRGKHKESETLTEQD-----------------LQLYCDFPNII 324 Query 385 HVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLC 435 V +K+ V+IH+QD K LE+ L S ALSFVSL+DGY+RLTAD+ HYLC Sbjct 325 DVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYYRLTADAHHYLC 384 Query 436 HEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQ 492 EVAPP ++ +I+ HGP+ F +KL+ + GLY++ S + LT A + Sbjct 385 KEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERE 444 Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552 + + K ++ + L G ++F S+++L Q +R+ + F +CC Sbjct 445 NVIEYKHCLITK----NENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCP 500 Query 553 PQPGETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVY 604 P+P + SNL++ R S R +++Q+ FH++ +++ LGQGT T ++ Sbjct 501 PKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIF 560 Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ--ELRVVLKVLDPSHHDIALAFYETASLM 662 +G R G D GQ E V+LKVLD +H + + +F+E AS+M Sbjct 561 KGVRREVG-------------------DYGQLHETEVLLKVLDKAHRNYSESFFEAASMM 601 Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASAL 722 S++SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+ VA+QLA A+ Sbjct 602 SKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAM 661 Query 723 SYLENKNLVHGNVCGRNILLARL-GLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781 +LE L+HGNVC +NILL R G PFIKLSDPG+ + L ++ ERIPW+ P Sbjct 662 HFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP 721 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL 841 EC+ N L+ A DKW FG TL EIC G+ PL + K FY+ +H+LP P +L Sbjct 722 ECIENPKN-LNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAEL 780 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA--------------S 887 A L + C+ YEP RPSFR I+RDL L + ++LT N P Sbjct 781 ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDY-ELLTENDMLPNMRIGALGFSGAFEDR 839 Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L+ +H +++E Sbjct 840 DPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST-EEHLRDFERE 898 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQ 1005 I+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I +LL + Sbjct 899 IEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTS 958 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 QIC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V+E G+SP+ Sbjct 959 QICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPI 1018 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQGQMTVLRL 1124 FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG QGQM V L Sbjct 1019 FWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHL 1078 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 ELL+ RLPRPD CP E+Y +M CW + RP+F +L + + + G Sbjct 1079 IELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG 1132 >sp|O19064|JAK2_PIG Tyrosine-protein kinase JAK2 OS=Sus scrofa OX=9823 GN=JAK2 PE=2 SV=1 Length=1131 Score = 759 bits (1959), Expect = 0.0, Method: Compositional matrix adjust. Identities = 450/1178 (38%), Positives = 644/1178 (55%), Gaps = 144/1178 (12%) Query 31 LLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHI 90 L H G G+ ++ F AEE+C+ + GITP ++FAL + ++W PPNH+ Sbjct 43 LYHSLGKAEGD-YLKFPAGEYVAEEICVAASKACGITPVYHSMFALMNETERIWYPPNHV 101 Query 91 LEIPRDASLMLYFRIRFYFRNWH--GMNPREPAVYRCG-PPGTEASSDQTAQGMQLLDPA 147 + + +RIRFYF W+ G N YR G G EA LLD Sbjct 102 FHVDESTRHNVLYRIRFYFPYWYCNGSN----RTYRHGISRGAEAP---------LLDDF 148 Query 148 SFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAK 207 YLF Q +H+F L+ H + E LGMA L + +A ++ Sbjct 149 VMSYLFAQWRHDF------LYGWVKIPVTHETQEECLGMAVLDMMRIAKEKDQTPLDIYS 202 Query 208 KTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLA 267 S+K +P+ R I+ + LTR R+R FRRF+ F + + + + +KYL LE L Sbjct 203 SVSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQFSHCKATARNLKLKYLINLETLQ 262 Query 268 PRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWW 327 F TE+ V ++ G P+ G E A +++TG GGIQW Sbjct 263 SAFYTEQFEV----------------KEPGRGPS--GEEIFAT-----IIITGNGGIQW- 298 Query 328 PVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVV 387 S G++ ++ ++ +CDF DI V Sbjct 299 --------------SRGKHKESETLTEQD-----------------LQLYCDFPDIIDVS 327 Query 388 LKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEV 438 +K+ V+IH+QD K LE+ L S ALSFVSL+DGY+RLTAD+ HYLC EV Sbjct 328 IKQANQEGSNESRIVTIHKQDGKSLEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEV 387 Query 439 APPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPD 495 APP ++ +I+ HGP+ F +KL+ + GL+++ S + LT A + Sbjct 388 APPMVLENIQSNCHGPISMDFAISKLKKAGNQTGLFVLRCSPKDFNKYFLTFAVERENVT 447 Query 496 GMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQP 555 + + K ++G + L G ++F ++++L Q +R+ F +CC P+P Sbjct 448 EYKHCLITK----NENGEYNLSGTRKNFSNLKDLLNCYQMETVRSDSIIFQFTKCCPPKP 503 Query 556 GETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 + SNL++ R S R N++Q+ FH++ +++ LGQGT T +++G Sbjct 504 KDKSNLLVFRTNGISDVPTSPTLQRHNNVNQMVFHKIRNEDLIFNESLGQGTFTKIFKGV 563 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQ--ELRVVLKVLDPSHHDIALAFYETASLMSQV 665 R G D GQ E V+LKVLD +H + + +F+E AS+MSQ+ Sbjct 564 RREVG-------------------DYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSQL 604 Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL 725 SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+ VA+QLA A+ +L Sbjct 605 SHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWAMHFL 664 Query 726 ENKNLVHGNVCGRNILLARL-GLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECL 784 E K L+HGNVC +NILL R G PFIKLSDPG+ + L ++ ERIPW+ PEC+ Sbjct 665 EEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECI 724 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATL 844 N L+ A DKW FG TL EIC G+ PL + K FY+ +H+LP P +LA L Sbjct 725 ENPKN-LNLATDKWSFGTTLWEICSGGDKPLNALDSQRKLQFYEDRHQLPAPKWTELANL 783 Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA--------------SDPT 890 + C+ YEP RPSFR I+RDL L + ++LT N P DPT Sbjct 784 INNCMDYEPDFRPSFRAIIRDLNSLFTPDY-ELLTENDMLPNMRIGALGFSGAFEDRDPT 842 Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L+ +H +++EI+I Sbjct 843 QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHST-EEHLRDFEREIEI 901 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQIC 1008 L++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I +LL + QIC Sbjct 902 LKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQIC 961 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V+E G+SP+FWY Sbjct 962 KGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWY 1021 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQGQMTVLRLTEL 1127 APE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG QGQM V L EL Sbjct 1022 APESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL 1081 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L+ RLPRPD CP E+Y +M CW + RP+F +L Sbjct 1082 LKNNGRLPRPDGCPDEIYIIMTECWNNNVNQRPSFRDL 1119 Score = 87.8 bits (216), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 95/364 (26%), Positives = 164/364 (45%), Gaps = 62/364 (17%) Query 837 SCPQLATLTSQCLTYEPTQ----RPSFRTILRDLTRLQPHNLADVLTVNPDSPA------ 886 +C Q+ T+ S + ++ T+ +P ++ +L + + ++DV P SP Sbjct 479 NCYQMETVRSDSIIFQFTKCCPPKPKDKS---NLLVFRTNGISDV----PTSPTLQRHNN 531 Query 887 SDPTVFHKRYLKKI---RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS- 942 + VFHK + + LG+G F K+ D G++ + L HR+ Sbjct 532 VNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGD-YGQLHETEVLLKVLDKAHRNY 590 Query 943 --GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLA 998 + + ++ L H+H++ G C GE+++ LV E+V GSL YL ++ SI + Sbjct 591 SESFFEAASMMSQLSHKHLVLNYGVCV-CGEENI-LVQEFVKFGSLDTYLKKNKNSINIL 648 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL--DNDR------LVKIGDFGLAKAV-P 1049 L A+Q+ M +L + IH ++ A+N+LL + DR +K+ D G++ V P Sbjct 649 WKLEVAKQLAWAMHFLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLP 708 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 + R+ W PEC++ K A+D WSFG TL+E+ C P Sbjct 709 KDILQERIP--------WVPPECIENPKNLNLATDKWSFGTTLWEI---CSGGDKP---- 753 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 + R + E +LP P E+ +L+ NC + E FRP+F +I Sbjct 754 -------LNALDSQRKLQFYEDRHQLPAPKWT--ELANLINNCMDYEPDFRPSFRAIIRD 804 Query 1169 LKTV 1172 L ++ Sbjct 805 LNSL 808 >sp|P52333|JAK3_HUMAN Tyrosine-protein kinase JAK3 OS=Homo sapiens OX=9606 GN=JAK3 PE=1 SV=2 Length=1124 Score = 684 bits (1766), Expect = 0.0, Method: Compositional matrix adjust. Identities = 463/1200 (39%), Positives = 630/1200 (53%), Gaps = 150/1200 (13%) Query 26 GGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWL 85 G L VLL GPG + ++FS AE++C+ A GI P +LFAL W Sbjct 24 GALHVLLPARGPGPPQ-RLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLSCWF 82 Query 86 PPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLD 145 PP+HI + ++ +L +RIRFYF NW G+ +R G AS+ +LD Sbjct 83 PPSHIFSVEDASTQVLLYRIRFYFPNWFGLE----KCHRFGLRKDLASA--------ILD 130 Query 146 PASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEV 205 E+LF Q + + V+ + LS +E+ E L +A L L +A E+ Sbjct 131 LPVLEHLFAQHRSDLVSGRLPV-GLSLKEQ-----GECLSLAVLDLARMAREQAQRPGEL 184 Query 206 AKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLER 265 K S+K C+P S R I+ S +TR R+R RR LR + + +M KY+ LER Sbjct 185 LKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLER 244 Query 266 LAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQ 325 L P E V G P + + V G GGI Sbjct 245 LDPAGAAETFHV----------GLPGALGGHDG--------------LGLLRVAGDGGIA 280 Query 326 WWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITH 385 W E+EV QP FCDF +I Sbjct 281 WTQGEQEVL-----------------------------QP-----------FCDFPEIVD 300 Query 386 VVLKE----------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLC 435 + +K+ V++ R DN+ LE P ALSFV+LVDGYFRLT DS H+ C Sbjct 301 ISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFC 360 Query 436 HEVAPPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTV-AQRS 491 EVAPPRL+ + + HGP+ F KL+ G Y++ S +LTV Q Sbjct 361 KEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNP 420 Query 492 QAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCC 551 PD L +R+ P G F+L G R S+REL A L +L CC Sbjct 421 LGPDYKGCL-IRRSPT----GTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCC 475 Query 552 LPQPGETSNLIIMRGARASPRT--------LNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603 +P+P E SNLI+++ + P + LSQ++FH++ + +LG G+ T + Sbjct 476 IPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKI 535 Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663 Y G R E +V G R E V+LKV+D H + +F E ASLMS Sbjct 536 YRG-CRHE---------------VVDGEARKTE--VLLKVMDAKHKNCMESFLEAASLMS 577 Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASAL 722 QVS+ HL +HGVC+ G ++ MV E+V G +D++LR+ RGH VP +WK+ V +QLA AL Sbjct 578 QVSYRHLVLLHGVCMAG-DSTMVQEFVHLGAIDMYLRK-RGHLVPASWKLQVVKQLAYAL 635 Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPE 782 +YLE+K L HGNV R +LLAR G A+G+ PFIKLSDPGV LS E +RIPW+APE Sbjct 636 NYLEDKGLPHGNVSARKVLLAREG-ADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPE 694 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLA 842 CL A +LS DKWGFGAT+ E+ P+ + P++K FY+ + +LP P +LA Sbjct 695 CL-REAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTELA 753 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA--------------SD 888 L QC+ YEP QRPSFR ++RDL L + + P + A D Sbjct 754 LLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQD 813 Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 PT+F +R+LK I LG+G+FG V L YDP D TG +VAVK L+ GP + +++EI Sbjct 814 PTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHS-GPDQQRDFQREI 872 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQ 1006 IL+ L+ + I+KY+G G +SL+LVMEY+P G LRD+L RH L ++LLL++ Q Sbjct 873 QILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQ 932 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 IC+GM YL ++ +HRDLAARN+L++++ VKI DFGLAK +P +YY VRE G SP+F Sbjct 933 ICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIF 992 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 WYAPE L + F SDVWSFGV LYEL T+CD S SP +FL ++G + + RL E Sbjct 993 WYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLE 1052 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 LLE G+RLP P CP EV+ LMK CW RP+F L P L + +G F+ Sbjct 1053 LLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAFTA 1112 >sp|Q62137|JAK3_MOUSE Tyrosine-protein kinase JAK3 OS=Mus musculus OX=10090 GN=Jak3 PE=1 SV=2 Length=1100 Score = 671 bits (1730), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/1166 (38%), Positives = 601/1166 (52%), Gaps = 149/1166 (13%) Query 44 VTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYF 103 ++FS AE++C+ A GI P +LFAL W PP+HI I + +L + Sbjct 41 LSFSFGDYLAEDLCVRAAKACGILPVYHSLFALATEDFSCWFPPSHIFCIEDVDTQVLVY 100 Query 104 RIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVND 163 R+RFYF +W G+ +R G D T+ +LD E+LF Q + + V+ Sbjct 101 RLRFYFPDWFGLE----TCHRFG-----LRKDLTSA---ILDLHVLEHLFAQHRSDLVSG 148 Query 164 VASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHI 223 + LS +E+ E L +A L L +A E+ K S+K C+P S R I Sbjct 149 RLPV-GLSMKEQ-----GEFLSLAVLDLAQMAREQAQRPGELLKTVSYKACLPPSLRDVI 202 Query 224 RQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLL 283 + + +TR R+R LR + + +M KY+ LERL P TE V L Sbjct 203 QGQNFVTRRRIRRTVVLALRRVVACQADRYALMAKYILDLERLHPAATTETFRVG----L 258 Query 284 AQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSS 343 A+ EP +R V G GI W SSG Sbjct 259 PGAQEEPGLLR-----------------------VAGDNGISW------------SSGD- 282 Query 344 GRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKE----------HCV 393 + L+ FCDF +I V +K+ V Sbjct 283 ---------------------------QELFQTFCDFPEIVDVSIKQAPRVGPAGEHRLV 315 Query 394 SIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHG 453 ++ R D LE P ALSFV+LVDGYFRL DS HY C EVAPPRL+ + HG Sbjct 316 TVTRMDGHILEAEFPGLPEALSFVALVDGYFRLICDSRHYFCKEVAPPRLLEEEAELCHG 375 Query 454 PLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQ 510 P+ F KL+ G Y++ S +LT ++ + +R+ P Sbjct 376 PITLDFAIHKLKAAGSLPGTYILRRSPQDYDSFLLTACVQTPLGPDYKGCLIRQDP---- 431 Query 511 DGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMR----- 565 GAF L G + S+REL AA LR +L CC P+P E SNLI++R Sbjct 432 SGAFSLVGLSQPHRSLRELLAACWNSGLRVDGAALNLTSCCAPRPKEKSNLIVVRRGCTP 491 Query 566 --GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 SP L+QLSFH + + +LG G+ T ++ GR R G+ + + Sbjct 492 APAPGCSPSCCALTQLSFHTIPTDSLEWHENLGHGSFTKIFRGRRREVVDGETHDSE--- 548 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 V+LKV+D H + +F E ASLMSQVS+ HL +HGVC+ G ++ Sbjct 549 ---------------VLLKVMDSRHRNCMESFLEAASLMSQVSYPHLVLLHGVCMAG-DS 592 Query 684 IMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 IMV E+V G +D++LR+ RGH V +WK+ V +QLA AL+YLE+K L HGNV R +LL Sbjct 593 IMVQEFVYLGAIDMYLRK-RGHLVSASWKLQVTKQLAYALNYLEDKGLPHGNVSARKVLL 651 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 AR G +G PFIKLSDPGV LS E +RIPW+APECL A +L DKWGFGA Sbjct 652 AREG-GDGNPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECL-QEAQTLCLEADKWGFGA 709 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 T E+ G A + S P++K FY+ Q +LP +LA L +QC+ Y+P +RPSFR I Sbjct 710 TTWEVFSGGPAHITSLEPAKKLKFYEDQGQLPALKWTELAGLITQCMAYDPGRRPSFRAI 769 Query 863 LRDLTRLQPHNLADVLTVNPDSPA--------------SDPTVFHKRYLKKIRDLGEGHF 908 LRDL L + + P P+ DP +F +R+LK I LG+G+F Sbjct 770 LRDLNGLITSDYELLSDPTPGIPSPRDELCGGAQLYACQDPAIFEERHLKYISLLGKGNF 829 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968 G V L YDP D TG +VAVK L+ GP + +++EI IL+ L+ + I+KY+G Sbjct 830 GSVELCRYDPLGDNTGPLVAVKQLQHS-GPDQQRDFQREIQILKALHSDFIVKYRGVSYG 888 Query 969 QGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 G +SL+LVMEY+P G LRD+L RH L +LLLFA QIC+GM YL A+ +HRDLAA Sbjct 889 PGRQSLRLVMEYLPSGCLRDFLQRHRARLHTDRLLLFAWQICKGMEYLGARRCVHRDLAA 948 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RN+L++++ VKI DFGLAK +P G +YY VRE G SP+FWYAPE L + F SDVWS Sbjct 949 RNILVESEAHVKIADFGLAKLLPLGKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWS 1008 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 FGV LYEL T+CD S SP +FL ++G + + RL ELL G RLP P CP EV Sbjct 1009 FGVVLYELFTYCDKSCSPSAEFLRMMGPEREGPPLCRLLELLAEGRRLPPPPTCPTEVQE 1068 Query 1147 LMKNCWETEASFRPTFENLIPILKTV 1172 LM+ CW RP F L P L + Sbjct 1069 LMQLCWAPSPHDRPAFGTLSPQLDAL 1094 >sp|Q63272|JAK3_RAT Tyrosine-protein kinase JAK3 OS=Rattus norvegicus OX=10116 GN=Jak3 PE=2 SV=2 Length=1100 Score = 660 bits (1704), Expect = 0.0, Method: Compositional matrix adjust. Identities = 439/1166 (38%), Positives = 601/1166 (52%), Gaps = 149/1166 (13%) Query 44 VTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYF 103 ++FS AE++C+ A GI P +LFAL W PP+HI I + +L + Sbjct 41 LSFSFGDYLAEDLCVRAAKACGILPVYHSLFALATEDLSCWFPPSHIFSIEDVDTQVLVY 100 Query 104 RIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVND 163 R+RFYF W G+ +R G D T+ +LD E+LF Q + + V+ Sbjct 101 RLRFYFPGWFGLE----TCHRFG-----LHKDLTSA---ILDVHVLEHLFAQHRSDLVSG 148 Query 164 VASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHI 223 + LS +++ E L +A L L +A + E+ K S+K C+P S R I Sbjct 149 RLPV-GLSLKDQ-----GEFLSLAVLDLAQMARKQAQRPGELLKSVSYKACLPPSLRDLI 202 Query 224 RQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLL 283 + S +TR R+R + LR + + +M KY+ LERL P TE V L Sbjct 203 QGQSFVTRRRIRRTVVQALRRVVACQADRYALMAKYILDLERLHPAATTESFLVG----L 258 Query 284 AQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSS 343 A+ EP +R VTG GI W ++E Sbjct 259 PGAQEEPGCLR-----------------------VTGDNGIAWSSKDQE----------- 284 Query 344 GRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKE----------HCV 393 L+ FCDF +I V +K+ V Sbjct 285 -----------------------------LFQTFCDFPEIVDVSIKQAPRVGPAGEHRLV 315 Query 394 SIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHG 453 +I R D LE P ALSFV+LVDGYFRL DS H+ C EVAPPRL+ + HG Sbjct 316 TITRMDGHILEAEFPGLPEALSFVALVDGYFRLICDSRHFFCKEVAPPRLLEEEAELCHG 375 Query 454 PLLEPFVQAKLRPEDGL---YLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQ 510 P+ F KL+ L Y++ S +LT ++ + +R+ P Sbjct 376 PITLDFAIHKLKAAGSLPGSYILRRSPQDYDSFLLTACVQTPLGPDYKGCLIRQDP---- 431 Query 511 DGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARA- 569 GAF L G + S++EL A L+ +L CC+P+P E SNLI++R R Sbjct 432 SGAFSLVGLSQLHRSLQELLTACWHSGLQVDGTALNLTSCCVPRPKEKSNLIVVRRGRNP 491 Query 570 ------SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 SP L++LSFH + + +LG G+ T ++ G R G+ + + Sbjct 492 TPAPGHSPSCCALTKLSFHTIPADSLEWHENLGHGSFTKIFHGHRREVVDGETHDTE--- 548 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 V+LKV+D H + +F E ASLMSQVS+ HL +HGVC+ G ++ Sbjct 549 ---------------VLLKVMDSRHQNCMESFLEAASLMSQVSYPHLVLLHGVCMAG-DS 592 Query 684 IMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 IMV E+V G +D +LR+ RGH VP +WK+ V +QLA AL+YLE+K L HGNV R +LL Sbjct 593 IMVQEFVYLGAIDTYLRK-RGHLVPASWKLQVTKQLAYALNYLEDKGLPHGNVSARKVLL 651 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 AR G+ +G PFIKLSDPGV LS E +RIPW+APECL A +L+ DKWGFGA Sbjct 652 AREGV-DGNPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECL-QEAGTLNLEADKWGFGA 709 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 T E+ + S P++K FY+ + +LP +L L +QC+ Y+P +RPSFR I Sbjct 710 TTWEVFSGAPMHITSLEPAKKLKFYEDRGQLPALKWTELEGLIAQCMAYDPGRRPSFRAI 769 Query 863 LRDLTRLQPHNLADVLTVNPDSP--------------ASDPTVFHKRYLKKIRDLGEGHF 908 LRDL L + + P P DP +F +R+LK I LG+G+F Sbjct 770 LRDLNGLITSDYELLSDPTPGIPNPRDELCGGAQLYACQDPAIFEERHLKYISLLGKGNF 829 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968 G V L YDP D TG +VAVK L+ GP+ + +++EI IL+ L+ + I+KY+G Sbjct 830 GSVELCRYDPLGDNTGPLVAVKQLQHS-GPEQQRDFQREIQILKALHCDFIVKYRGVSYG 888 Query 969 QGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 G +SL+LVMEY+P G LRD+L RH L +LLLFA QIC+GM YL A+ +HRDLAA Sbjct 889 PGRQSLRLVMEYLPSGCLRDFLQRHRARLHNDRLLLFAWQICKGMEYLGARRCVHRDLAA 948 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RN+L++++ VKI DFGLAK +P G +YY VRE G SP+FWYAPE L + F SDVWS Sbjct 949 RNILVESEAHVKIADFGLAKLLPLGKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWS 1008 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 FGV LYEL T+ D S SP T+FL ++G + + L ELL G RLP P CP EV Sbjct 1009 FGVVLYELFTYSDKSCSPSTEFLRMMGPEREGSPLCHLLELLAEGRRLPPPSTCPTEVQE 1068 Query 1147 LMKNCWETEASFRPTFENLIPILKTV 1172 LM+ CW RP F+ L P L + Sbjct 1069 LMQLCWSPNPQDRPAFDTLSPQLDAL 1094 >sp|O54967|ACK1_MOUSE Activated CDC42 kinase 1 OS=Mus musculus OX=10090 GN=Tnk2 PE=1 SV=2 Length=1055 Score = 182 bits (461), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 109/279 (39%), Positives = 158/279 (57%), Gaps = 21/279 (8%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEI 948 + ++ L+ + LG+G FG V +D G VAVK LK D P+ + +E+ Sbjct 120 LIGEKDLRLLEKLGDGSFGVVRRGEWD-APAGKTVSVAVKCLKPDVLSQPEAMDDFIREV 178 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006 + + +L H ++I+ G +++V E PLGSL D L +H L L +A Q Sbjct 179 NAMHSLDHRNLIRLYGVVL---TLPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQ 235 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 + EGMAYL ++ +IHRDLAARN+LL LVKIGDFGL +A+P+ ++Y ++E P Sbjct 236 VAEGMAYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFA 295 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE LK F +ASD W FGVTL+E+ T+ Q P IG+ Q+ L + Sbjct 296 WCAPESLKTRTFSHASDTWMFGVTLWEMFTY---GQEP------WIGLNGSQI----LHK 342 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + GERLPRP+ CP ++Y++M CW + RPTF L Sbjct 343 IDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVAL 381 Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 78/255 (31%), Positives = 119/255 (47%), Gaps = 25/255 (10%) Query 634 GQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 G+ + V +K L P S + F + M + H +L ++GV + P MVTE Sbjct 150 GKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTLPMK-MVTELA 208 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L LR+ +GH + A Q+A ++YLE+K +H ++ RN+LLA Sbjct 209 PLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMAYLESKRFIHRDLAARNLLLA------- 261 Query 751 TSPFIKLSDPGVGLGALS--------REERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 T +K+ D G+ + AL +E R W APE L + S A D W FG Sbjct 262 TRDLVKIGDFGL-MRALPQNDDHYVMQEHRKVPFAWCAPESL--KTRTFSHASDTWMFGV 318 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEP-SCPQ-LATLTSQCLTYEPTQRPSF 859 TL E+ G+ P + S+ H ++ RLP P CPQ + + QC ++P RP+F Sbjct 319 TLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTF 378 Query 860 RTILRDLTRLQPHNL 874 + L QP ++ Sbjct 379 VALRDFLLEAQPTDM 393 >sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens OX=9606 GN=TNK2 PE=1 SV=3 Length=1038 Score = 181 bits (458), Expect = 5e-45, Method: Compositional matrix adjust. Identities = 108/279 (39%), Positives = 157/279 (56%), Gaps = 21/279 (8%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEI 948 + ++ L+ + LG+G FG V +D G VAVK LK D P+ + +E+ Sbjct 120 LIGEKDLRLLEKLGDGSFGVVRRGEWD-APSGKTVSVAVKCLKPDVLSQPEAMDDFIREV 178 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006 + + +L H ++I+ G +++V E PLGSL D L +H L L +A Q Sbjct 179 NAMHSLDHRNLIRLYGVVL---TPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQ 235 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 + EGM YL ++ +IHRDLAARN+LL LVKIGDFGL +A+P+ ++Y ++E P Sbjct 236 VAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFA 295 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE LK F +ASD W FGVTL+E+ T+ Q P IG+ Q+ L + Sbjct 296 WCAPESLKTRTFSHASDTWMFGVTLWEMFTY---GQEP------WIGLNGSQI----LHK 342 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + GERLPRP+ CP ++Y++M CW + RPTF L Sbjct 343 IDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVAL 381 Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 78/255 (31%), Positives = 118/255 (46%), Gaps = 25/255 (10%) Query 634 GQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 G+ + V +K L P S + F + M + H +L ++GV + P MVTE Sbjct 150 GKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMK-MVTELA 208 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L LR+ +GH + A Q+A + YLE+K +H ++ RN+LLA Sbjct 209 PLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLA------- 261 Query 751 TSPFIKLSDPGVGLGALS--------REERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 T +K+ D G+ + AL +E R W APE L + S A D W FG Sbjct 262 TRDLVKIGDFGL-MRALPQNDDHYVMQEHRKVPFAWCAPESL--KTRTFSHASDTWMFGV 318 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEP-SCPQ-LATLTSQCLTYEPTQRPSF 859 TL E+ G+ P + S+ H ++ RLP P CPQ + + QC ++P RP+F Sbjct 319 TLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTF 378 Query 860 RTILRDLTRLQPHNL 874 + L QP ++ Sbjct 379 VALRDFLLEAQPTDM 393 >sp|Q17R13|ACK1_BOVIN Activated CDC42 kinase 1 OS=Bos taurus OX=9913 GN=TNK2 PE=1 SV=1 Length=1039 Score = 179 bits (454), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 109/279 (39%), Positives = 154/279 (55%), Gaps = 21/279 (8%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEI 948 + ++ L LG+G FG V +D G VAVK LK D P+ + +E+ Sbjct 120 LIGEKDLHLFEKLGDGSFGVVRRGEWD-APSGKTVSVAVKCLKPDVLSQPEAMDDFIREV 178 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006 + + +L H ++I+ G ++ V E PLGSL D L +H L L +A Q Sbjct 179 NAMHSLDHRNLIRLYGVVL---TPPMKTVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQ 235 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 + EGM YL A+ +IHRDLAARN+LL LVKIGDFGL +A+P+ ++Y ++E P Sbjct 236 VAEGMGYLEAKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFA 295 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE LK F +ASD W FGVTL+E+ T+ Q P IG+ Q+ L + Sbjct 296 WCAPESLKTRTFSHASDTWMFGVTLWEMFTY---GQEP------WIGLNGSQI----LHK 342 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + GERLPRP+ CP ++Y++M CW + RPTF L Sbjct 343 IDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVAL 381 Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 77/255 (30%), Positives = 116/255 (45%), Gaps = 25/255 (10%) Query 634 GQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 G+ + V +K L P S + F + M + H +L ++GV + P VTE Sbjct 150 GKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKT-VTELA 208 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L LR+ +GH + A Q+A + YLE K +H ++ RN+LLA Sbjct 209 PLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLEAKRFIHRDLAARNLLLA------- 261 Query 751 TSPFIKLSDPGVGLGALS--------REERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 T +K+ D G+ + AL +E R W APE L + S A D W FG Sbjct 262 TRDLVKIGDFGL-MRALPQNDDHYVMQEHRKVPFAWCAPESL--KTRTFSHASDTWMFGV 318 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEP-SCPQ-LATLTSQCLTYEPTQRPSF 859 TL E+ G+ P + S+ H ++ RLP P CPQ + + QC ++P RP+F Sbjct 319 TLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTF 378 Query 860 RTILRDLTRLQPHNL 874 + L QP ++ Sbjct 379 VALRDFLLEAQPTDM 393 >sp|Q5U2X5|ACK1_RAT Activated CDC42 kinase 1 OS=Rattus norvegicus OX=10116 GN=Tnk2 PE=2 SV=1 Length=1040 Score = 179 bits (454), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 108/279 (39%), Positives = 156/279 (56%), Gaps = 21/279 (8%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEI 948 + ++ L+ + LG+G FG V +D G VAVK LK D P+ + +E+ Sbjct 120 LIGEKDLRLLEKLGDGSFGVVRRGEWD-APAGKTVSVAVKCLKPDVLSQPEAMDDFIREV 178 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006 + + +L H ++I+ G +++V E PLGSL D L +H L L +A Q Sbjct 179 NAMHSLDHRNLIRLYGVVL---TPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQ 235 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 + EGM YL ++ +IHRDLAARN+LL LVKIGDFGL +A+P+ +Y ++E P Sbjct 236 VAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDGHYVMQEHRKVPFA 295 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE LK F +ASD W FGVTL+E+ T+ Q P IG+ Q+ L + Sbjct 296 WCAPESLKTRTFSHASDTWMFGVTLWEMFTY---GQEP------WIGLNGSQI----LHK 342 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + GERLPRP+ CP ++Y++M CW + RPTF L Sbjct 343 IDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVAL 381 Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 78/255 (31%), Positives = 118/255 (46%), Gaps = 25/255 (10%) Query 634 GQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 G+ + V +K L P S + F + M + H +L ++GV + P MVTE Sbjct 150 GKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMK-MVTELA 208 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L LR+ +GH + A Q+A + YLE+K +H ++ RN+LLA Sbjct 209 PLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLA------- 261 Query 751 TSPFIKLSDPGVGLGALS--------REERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 T +K+ D G+ + AL +E R W APE L + S A D W FG Sbjct 262 TRDLVKIGDFGL-MRALPQNDGHYVMQEHRKVPFAWCAPESL--KTRTFSHASDTWMFGV 318 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEP-SCPQ-LATLTSQCLTYEPTQRPSF 859 TL E+ G+ P + S+ H ++ RLP P CPQ + + QC ++P RP+F Sbjct 319 TLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTF 378 Query 860 RTILRDLTRLQPHNL 874 + L QP ++ Sbjct 379 VALRDFLLEAQPTDM 393 >sp|P24786|NTRK3_PIG NT-3 growth factor receptor OS=Sus scrofa OX=9823 GN=NTRK3 PE=2 SV=1 Length=825 Score = 177 bits (450), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 111/287 (39%), Positives = 152/287 (53%), Gaps = 36/287 (13%) Query 901 RDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 R+LGEG FGKV L CY+ + +VAVKALK D R +++E ++L L HEHI Sbjct 542 RELGEGAFGKVFLAECYNLSPTKVKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHI 600 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLL 1002 +K+ G C D L +V EY+ G L +L H +GL+Q+L Sbjct 601 VKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLH 658 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 A QIC GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV Sbjct 659 IASQICSGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDV-YSTDYYRVGGHTM 717 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 P+ W PE + KF SDVWSFGV L+E+ T+ + P Q++ Sbjct 718 LPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY---GKQP-----------WFQLSNT 763 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + E + +G L RP CP EVY +M CW+ E R + + IL Sbjct 764 EVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810 Score = 78.2 bits (191), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 63/238 (26%), Positives = 105/238 (44%), Gaps = 32/238 (13%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL--------------- 699 F A L++ + H H+ +GVC G IMV EY++HG L+ +L Sbjct 585 FQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQP 644 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R+ +G + ++ + +A Q+ S + YL +++ VH ++ RN L+ G + +K+ D Sbjct 645 RQAKGELGLSQMLHIASQICSGMVYLASQHFVHRDLATRNCLV-------GANLLVKIGD 697 Query 760 PGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ S + + I W+ PE + +T D W FG L EI G+ Sbjct 698 FGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGVILWEIFTYGKQ 755 Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 P S +E + L P CP ++ + C EP QR + + I + L L Sbjct 756 PWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813 >sp|Q91044|NTRK3_CHICK NT-3 growth factor receptor OS=Gallus gallus OX=9031 GN=NTRK3 PE=1 SV=2 Length=827 Score = 177 bits (448), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 114/289 (39%), Positives = 154/289 (53%), Gaps = 40/289 (14%) Query 901 RDLGEGHFGKVSLY-CYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 R+LGEG FGKV L CY+ PTND +VAVKALK D R +++E ++L L HE Sbjct 544 RELGEGAFGKVFLAECYNLSPTNDKM--LVAVKALK-DPTLAARKDFQREAELLTNLQHE 600 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQL 1000 HI+K+ G C D L +V EY+ G L +L H +GL+Q+ Sbjct 601 HIVKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQM 658 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 L A QI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV Sbjct 659 LHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDV-YSTDYYRVGGH 717 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 P+ W PE + KF SDVWSFGV L+E+ T+ + P Q++ Sbjct 718 TMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY---GKQP-----------WFQLS 763 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + E + +G L RP CP EVY +M CW+ E R + + IL Sbjct 764 NTEVIECITQGRVLERPRVCPKEVYDIMLGCWQREPQQRLNIKEIYKIL 812 Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 64/238 (27%), Positives = 106/238 (45%), Gaps = 32/238 (13%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL--------------- 699 F A L++ + H H+ +GVC G IMV EY++HG L+ +L Sbjct 587 FQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQP 646 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R+ +G + ++ + +A Q+AS + YL +++ VH ++ RN L+ G + +K+ D Sbjct 647 RQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV-------GANLLVKIGD 699 Query 760 PGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ S + + I W+ PE + +T D W FG L EI G+ Sbjct 700 FGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGVILWEIFTYGKQ 757 Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 P S +E + L P CP ++ + C EP QR + + I + L L Sbjct 758 PWFQLSNTEVIECITQGRVLERPRVCPKEVYDIMLGCWQREPQQRLNIKEIYKILHAL 815 >sp|Q5IS37|NTRK3_PANTR NT-3 growth factor receptor OS=Pan troglodytes OX=9598 GN=NTRK3 PE=2 SV=1 Length=825 Score = 174 bits (441), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 113/289 (39%), Positives = 153/289 (53%), Gaps = 40/289 (14%) Query 901 RDLGEGHFGKVSLY-CYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 R+LGEG FGKV L CY+ PT D +VAVKALK D R +++E ++L L HE Sbjct 542 RELGEGAFGKVFLAECYNLSPTKDKM--LVAVKALK-DPTLAARKDFQREAELLTNLQHE 598 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQL 1000 HI+K+ G C D L +V EY+ G L +L H +GL+Q+ Sbjct 599 HIVKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQM 656 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 L A QI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV Sbjct 657 LHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDV-YSTDYYRVGGH 715 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 P+ W PE + KF SDVWSFGV L+E+ T+ + P Q++ Sbjct 716 TMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY---GKQP-----------WFQLS 761 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + E + +G L RP CP EVY +M CW+ E R + + IL Sbjct 762 NTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810 Score = 80.9 bits (198), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 70/266 (26%), Positives = 116/266 (44%), Gaps = 35/266 (13%) Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 L P +D+ + V +K L F A L++ + H H+ +GVC G IMV Sbjct 560 LSPTKDK---MLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMV 616 Query 687 TEYVEHGPLDVWL---------------RRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 EY++HG L+ +L R+ +G + ++ + +A Q+AS + YL +++ V Sbjct 617 FEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFV 676 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785 H ++ RN L+ G + +K+ D G+ S + + I W+ PE + Sbjct 677 HRDLATRNCLV-------GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESI- 728 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLAT 843 +T D W FG L EI G+ P S +E + L P CP ++ Sbjct 729 -MYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYD 787 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869 + C EP QR + + I + L L Sbjct 788 VMLGCWQREPQQRLNIKEIYKILHAL 813 >sp|Q5IFJ9|NTRK3_MACFA NT-3 growth factor receptor OS=Macaca fascicularis OX=9541 GN=NTRK3 PE=2 SV=1 Length=825 Score = 174 bits (441), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 113/289 (39%), Positives = 153/289 (53%), Gaps = 40/289 (14%) Query 901 RDLGEGHFGKVSLY-CYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 R+LGEG FGKV L CY+ PT D +VAVKALK D R +++E ++L L HE Sbjct 542 RELGEGAFGKVFLAECYNLSPTKDKM--LVAVKALK-DPTLAARKDFQREAELLTNLQHE 598 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQL 1000 HI+K+ G C D L +V EY+ G L +L H +GL+Q+ Sbjct 599 HIVKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQM 656 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 L A QI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV Sbjct 657 LHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDV-YSTDYYRVGGH 715 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 P+ W PE + KF SDVWSFGV L+E+ T+ + P Q++ Sbjct 716 TMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY---GKQP-----------WFQLS 761 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + E + +G L RP CP EVY +M CW+ E R + + IL Sbjct 762 NTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810 Score = 80.9 bits (198), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 70/266 (26%), Positives = 116/266 (44%), Gaps = 35/266 (13%) Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 L P +D+ + V +K L F A L++ + H H+ +GVC G IMV Sbjct 560 LSPTKDK---MLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMV 616 Query 687 TEYVEHGPLDVWL---------------RRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 EY++HG L+ +L R+ +G + ++ + +A Q+AS + YL +++ V Sbjct 617 FEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFV 676 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785 H ++ RN L+ G + +K+ D G+ S + + I W+ PE + Sbjct 677 HRDLATRNCLV-------GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM 729 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLAT 843 +T D W FG L EI G+ P S +E + L P CP ++ Sbjct 730 --YRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYD 787 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869 + C EP QR + + I + L L Sbjct 788 VMLGCWQREPQQRLNIKEIYKILHAL 813 >sp|Q6VNS1|NTRK3_MOUSE NT-3 growth factor receptor OS=Mus musculus OX=10090 GN=Ntrk3 PE=1 SV=1 Length=825 Score = 174 bits (440), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 113/289 (39%), Positives = 153/289 (53%), Gaps = 40/289 (14%) Query 901 RDLGEGHFGKVSLY-CYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 R+LGEG FGKV L CY+ PT D +VAVKALK D R +++E ++L L HE Sbjct 542 RELGEGAFGKVFLAECYNLSPTKDKM--LVAVKALK-DPTLAARKDFQREAELLTNLQHE 598 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQL 1000 HI+K+ G C D L +V EY+ G L +L H +GL+Q+ Sbjct 599 HIVKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQM 656 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 L A QI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV Sbjct 657 LHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDV-YSTDYYRVGGH 715 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 P+ W PE + KF SDVWSFGV L+E+ T+ + P Q++ Sbjct 716 TMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY---GKQP-----------WFQLS 761 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + E + +G L RP CP EVY +M CW+ E R + + IL Sbjct 762 NTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810 Score = 80.9 bits (198), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 70/266 (26%), Positives = 116/266 (44%), Gaps = 35/266 (13%) Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 L P +D+ + V +K L F A L++ + H H+ +GVC G IMV Sbjct 560 LSPTKDK---MLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMV 616 Query 687 TEYVEHGPLDVWL---------------RRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 EY++HG L+ +L R+ +G + ++ + +A Q+AS + YL +++ V Sbjct 617 FEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFV 676 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785 H ++ RN L+ G + +K+ D G+ S + + I W+ PE + Sbjct 677 HRDLATRNCLV-------GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM 729 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLAT 843 +T D W FG L EI G+ P S +E + L P CP ++ Sbjct 730 --YRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYD 787 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869 + C EP QR + + I + L L Sbjct 788 VMLGCWQREPQQRLNIKEIYKILHAL 813 >sp|Q3UFB7|NTRK1_MOUSE High affinity nerve growth factor receptor OS=Mus musculus OX=10090 GN=Ntrk1 PE=1 SV=2 Length=799 Score = 173 bits (438), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 113/316 (36%), Positives = 159/316 (50%), Gaps = 46/316 (15%) Query 887 SDPTVFHKRYLKKIR--DLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSG 943 SD V H + I +LGEG FGKV L CY+ ND +VAVKALK + R Sbjct 501 SDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALK-EASENARQD 559 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------- 994 +++E ++L L H+HI+++ G C + G L +V EY+ G L +L H Sbjct 560 FQREAELLTMLQHQHIVRFFGVCTEGG--PLLMVFEYMRHGDLNRFLRSHGPDAKLLAGG 617 Query 995 -------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 +GL QLL A Q+ GM YL + H++HRDLA RN L+ +VKIGDFG+++ Sbjct 618 EDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRD 677 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + +YYRV P+ W PE + KF SDVWSFGV L+E+ T+ Sbjct 678 I-YSTDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYGKQPWY---- 732 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 Q++ E + +G L RP CP +VY +M+ CW+ E R + Sbjct 733 ----------QLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLS------ 776 Query 1168 ILKTVHEKYQ--GQAP 1181 +K VH + Q QAP Sbjct 777 -MKDVHARLQALAQAP 791 Score = 80.5 bits (197), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 80/327 (24%), Positives = 129/327 (39%), Gaps = 52/327 (16%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 S H + +++I LG+G V+ ++D+D ++ Sbjct 500 FSDTCVHHIKRQDIILKWELGEGAFGKVFLAECY---------NLLNDQDKML------- 543 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K L + + F A L++ + H H+ GVC G +MV EY+ HG L Sbjct 544 ---VAVKALKEASENARQDFQREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDL 600 Query 696 DVWLRRER--------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 + +LR G + + + VA Q+A+ + YL + + VH ++ RN L Sbjct 601 NRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCL 660 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAM 795 + G +K+ D G+ S + + I W+ PE + ST Sbjct 661 V-------GQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESIL--YRKFSTES 711 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEP 853 D W FG L EI G+ P S +E + L P +C P + + C EP Sbjct 712 DVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREP 771 Query 854 TQRPSFRTILRDLTRL--QPHNLADVL 878 QR S + + L L P + DVL Sbjct 772 QQRLSMKDVHARLQALAQAPPSYLDVL 798 >sp|Q5IS82|NTRK3_SAIBB NT-3 growth factor receptor OS=Saimiri boliviensis boliviensis OX=39432 GN=NTRK3 PE=2 SV=1 Length=825 Score = 172 bits (436), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 112/289 (39%), Positives = 152/289 (53%), Gaps = 40/289 (14%) Query 901 RDLGEGHFGKVSLY-CYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 R+LGEG FGKV L CY+ PT D +VAVKALK D R +++E ++L L HE Sbjct 542 RELGEGAFGKVFLAECYNLSPTKDKM--LVAVKALK-DPTLAARKDFQREAELLTNLQHE 598 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQL 1000 HI+K+ G C D L +V EY+ G L +L H +GL+Q+ Sbjct 599 HIVKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPXQAKGELGLSQM 656 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 L A QI GM YL +QH++HRDLA RN + + LVKIGDFG+++ V +YYRV Sbjct 657 LHIASQIASGMVYLASQHFVHRDLATRNCXVGANLLVKIGDFGMSRDV-YSTDYYRVGGH 715 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 P+ W PE + KF SDVWSFGV L+E+ T+ + P Q++ Sbjct 716 TMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY---GKQP-----------WFQLS 761 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + E + +G L RP CP EVY +M CW+ E R + + IL Sbjct 762 NTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810 Score = 78.6 bits (192), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 69/266 (26%), Positives = 115/266 (43%), Gaps = 35/266 (13%) Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 L P +D+ + V +K L F A L++ + H H+ +GVC G IMV Sbjct 560 LSPTKDK---MLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMV 616 Query 687 TEYVEHGPLDVWLR---------------RERGHVPMAWKMVVAQQLASALSYLENKNLV 731 EY++HG L+ +LR + +G + ++ + +A Q+AS + YL +++ V Sbjct 617 FEYMKHGDLNKFLRAHGPDAMILVDGQPXQAKGELGLSQMLHIASQIASGMVYLASQHFV 676 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785 H ++ RN + G + +K+ D G+ S + + I W+ PE + Sbjct 677 HRDLATRNCXV-------GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESI- 728 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLAT 843 +T D W FG L EI G+ P S +E + L P CP ++ Sbjct 729 -MYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYD 787 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869 + C EP QR + + I + L L Sbjct 788 VMLGCWQREPQQRLNIKEIYKILHAL 813 >sp|P35739|NTRK1_RAT High affinity nerve growth factor receptor OS=Rattus norvegicus OX=10116 GN=Ntrk1 PE=1 SV=1 Length=799 Score = 171 bits (434), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 114/316 (36%), Positives = 160/316 (51%), Gaps = 46/316 (15%) Query 887 SDPTVFHKRYLKKIR--DLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSG 943 SD V H + I +LGEG FGKV L CY+ ND +VAVKALK + R Sbjct 501 SDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALK-ETSENARQD 559 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------- 994 + +E ++L L H+HI+++ G C + G L +V EY+ G L +L H Sbjct 560 FHREAELLTMLQHQHIVRFFGVCTEGG--PLLMVFEYMRHGDLNRFLRSHGPDAKLLAGG 617 Query 995 -------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 +GL QLL A Q+ GM YL + H++HRDLA RN L+ +VKIGDFG+++ Sbjct 618 EDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRD 677 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + +YYRV P+ W PE + KF SDVWSFGV L+E+ T+ + P Sbjct 678 I-YSTDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTY---GKQPWY- 732 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 Q++ E + +G L RP CP +VY +M+ CW+ E R + Sbjct 733 ----------QLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLS------ 776 Query 1168 ILKTVHEKYQ--GQAP 1181 +K VH + Q QAP Sbjct 777 -MKDVHARLQALAQAP 791 Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 80/327 (24%), Positives = 130/327 (40%), Gaps = 52/327 (16%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 S H + +++I LG+G V+ ++D+D ++ Sbjct 500 FSDTCVHHIKRQDIILKWELGEGAFGKVFLAECY---------NLLNDQDKML------- 543 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K L + + F+ A L++ + H H+ GVC G +MV EY+ HG L Sbjct 544 ---VAVKALKETSENARQDFHREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDL 600 Query 696 DVWLRRER--------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 + +LR G + + + VA Q+A+ + YL + + VH ++ RN L Sbjct 601 NRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCL 660 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAM 795 + G +K+ D G+ S + + I W+ PE + ST Sbjct 661 V-------GQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESIL--YRKFSTES 711 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEP 853 D W FG L EI G+ P S +E + L P +C P + + C EP Sbjct 712 DVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREP 771 Query 854 TQRPSFRTILRDLTRL--QPHNLADVL 878 QR S + + L L P + DVL Sbjct 772 QQRLSMKDVHARLQALAQAPPSYLDVL 798 >sp|Q63604|NTRK2_RAT BDNF/NT-3 growth factors receptor OS=Rattus norvegicus OX=10116 GN=Ntrk2 PE=1 SV=1 Length=821 Score = 171 bits (433), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 110/295 (37%), Positives = 153/295 (52%), Gaps = 35/295 (12%) Query 893 HKRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 H LK R+LGEG FGKV L CY+ + +VAVK LK D R + +E ++L Sbjct 535 HNIVLK--RELGEGAFGKVFLAECYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELL 591 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------------IGL 997 L HEHI+K+ G C + L +V EY+ G L +L H + Sbjct 592 TNLQHEHIVKFYGVCVEG--DPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 649 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 +Q+L AQQI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV Sbjct 650 SQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV-YSTDYYRV 708 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 P+ W PE + KF SDVWS GV L+E+ T+ + P Sbjct 709 GGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTY---GKQP-----------WY 754 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 Q++ + E + +G L RP CP EVY LM CW+ E R +N+ +L+ + Sbjct 755 QLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHTRKNIKNIHTLLQNL 809 Score = 87.4 bits (215), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 75/271 (28%), Positives = 121/271 (45%), Gaps = 41/271 (15%) Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 L P +D+ + V +K L + + F+ A L++ + H H+ +GVCV G IMV Sbjct 559 LCPEQDK---ILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMV 615 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMV---------------VAQQLASALSYLENKNLV 731 EY++HG L+ +L R H P A M +AQQ+A+ + YL +++ V Sbjct 616 FEYMKHGDLNKFL---RAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFV 672 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785 H ++ RN L+ G + +K+ D G+ S + + I W+ PE + Sbjct 673 HRDLATRNCLV-------GENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESI- 724 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LAT 843 +T D W G L EI G+ P S +E + L P +CPQ + Sbjct 725 -MYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYE 783 Query 844 LTSQCLTYEPTQRPSFR---TILRDLTRLQP 871 L C EP R + + T+L++L + P Sbjct 784 LMLGCWQREPHTRKNIKNIHTLLQNLAKASP 814 >sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens OX=9606 GN=LYN PE=1 SV=3 Length=512 Score = 164 bits (416), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 101/286 (35%), Positives = 152/286 (53%), Gaps = 28/286 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +K ++ LG G FG+V + Y N+ T VAVK LK G + +E ++++TL H Sbjct 247 IKLVKRLGAGQFGEVWMGYY---NNSTK--VAVKTLKP--GTMSVQAFLEEANLMKTLQH 299 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAY 1013 + +++ E+ + ++ EY+ GSL D+L G L +L+ F+ QI EGMAY Sbjct 300 DKLVRLYAVV--TREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAY 357 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + ++YIHRDL A NVL+ + KI DFGLA+ + + Y RE P+ W APE + Sbjct 358 IERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAI 415 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 F SDVWSFG+ LYE++T+ I T + L +G R Sbjct 416 NFGCFTIKSDVWSFGILLYEIVTYGK--------------IPYPGRTNADVMTALSQGYR 461 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +PR + CP E+Y +MK CW+ +A RPTF+ L +L + +GQ Sbjct 462 MPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQ 507 Score = 87.0 bits (214), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 64/241 (27%), Positives = 115/241 (48%), Gaps = 23/241 (10%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P + AF E A+LM + H L ++ V R ++TEY+ G L Sbjct 271 KVAVKTLKPGTMSVQ-AFLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLD 329 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ + G + K++ + Q+A ++Y+E KN +H ++ N+L++ S K Sbjct 330 FLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSE-------SLMCK 382 Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 ++D G+ + E R I W APE + G ++ + D W FG L EI Sbjct 383 IADFGLAR-VIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKS--DVWSFGILLYEIVTY 439 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSF---RTILRD 865 G+ P R+ ++ + +R+P +CP +L + C + +RP+F +++L D Sbjct 440 GKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDD 499 Query 866 L 866 Sbjct 500 F 500 >sp|Q16620|NTRK2_HUMAN BDNF/NT-3 growth factors receptor OS=Homo sapiens OX=9606 GN=NTRK2 PE=1 SV=1 Length=822 Score = 169 bits (428), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 109/295 (37%), Positives = 152/295 (52%), Gaps = 35/295 (12%) Query 893 HKRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 H LK R+LGEG FGKV L CY+ + +VAVK LK D R + +E ++L Sbjct 536 HNIVLK--RELGEGAFGKVFLAECYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELL 592 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------------IGL 997 L HEHI+K+ G C + L +V EY+ G L +L H + Sbjct 593 TNLQHEHIVKFYGVCVEG--DPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 650 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 +Q+L AQQI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV Sbjct 651 SQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV-YSTDYYRV 709 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 P+ W PE + KF SDVWS GV L+E+ T+ + P Sbjct 710 GGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTY---GKQP-----------WY 755 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 Q++ + E + +G L RP CP EVY LM CW+ E R + + +L+ + Sbjct 756 QLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQNL 810 Score = 87.8 bits (216), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 75/271 (28%), Positives = 121/271 (45%), Gaps = 41/271 (15%) Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 L P +D+ + V +K L + + F+ A L++ + H H+ +GVCV G IMV Sbjct 560 LCPEQDK---ILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMV 616 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMV---------------VAQQLASALSYLENKNLV 731 EY++HG L+ +L R H P A M +AQQ+A+ + YL +++ V Sbjct 617 FEYMKHGDLNKFL---RAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFV 673 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785 H ++ RN L+ G + +K+ D G+ S + + I W+ PE + Sbjct 674 HRDLATRNCLV-------GENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESI- 725 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LAT 843 +T D W G L EI G+ P S +E + L P +CPQ + Sbjct 726 -MYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYE 784 Query 844 LTSQCLTYEPTQRPSFR---TILRDLTRLQP 871 L C EP R + + T+L++L + P Sbjct 785 LMLGCWQREPHMRKNIKGIHTLLQNLAKASP 815 >sp|F1N9Y5|KSYK_CHICK Tyrosine-protein kinase SYK OS=Gallus gallus OX=9031 GN=SYK PE=1 SV=2 Length=613 Score = 166 bits (421), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 103/290 (36%), Positives = 149/290 (51%), Gaps = 29/290 (10%) Query 883 DSPASDPTVFHKRYLKKIR--------DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 +SP +DP + + R +LG G+FG V Y + VAVK LK Sbjct 327 ESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGA--KPVAVKILKN 384 Query 935 DCG-PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993 + P + +E ++++ L + +I++ G CE + + LVME LG L +L ++ Sbjct 385 ESNDPAIKDELLREANVMQQLDNPYIVRMIGICEAE---AWMLVMEMAELGPLNKFLQKN 441 Query 994 S-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 + + Q+ GM YL +++HRDLAARNVLL KI DFGL+KA+ Sbjct 442 RHVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLVTQHYAKISDFGLSKALSADE 501 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 YY+ + G PV WYAPEC+ YKF SDVWSFGV ++E ++ Q P Sbjct 502 NYYKAQSHGKWPVKWYAPECMNFYKFSSKSDVWSFGVLMWEAFSY---GQKP------YK 552 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 G+ G+ + +++ERGER+ P+ CP EVY LMK CW RP F Sbjct 553 GMKGGE-----VAQMIERGERMECPEACPVEVYDLMKLCWTYNVDDRPGF 597 Score = 89.4 bits (220), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 66/236 (28%), Positives = 108/236 (46%), Gaps = 24/236 (10%) Query 639 VVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K+L +D A+ A++M Q+ + ++ + G+C ++V E E GPL+ Sbjct 377 VAVKILKNESNDPAIKDELLREANVMQQLDNPYIVRMIGIC-EAEAWMLVMEMAELGPLN 435 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L++ R HV + Q++ + YLE N VH ++ RN+LL T + K Sbjct 436 KFLQKNR-HVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVLLV-------TQHYAK 487 Query 757 LSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 +SD G+ ALS +E + + W APEC+ S+ D W FG + E Sbjct 488 ISDFGLS-KALSADENYYKAQSHGKWPVKWYAPECM--NFYKFSSKSDVWSFGVLMWEAF 544 Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTI 862 G+ P + E +R R+ P +CP ++ L C TY RP F + Sbjct 545 SYGQKPYKGMKGGEVAQMIERGERMECPEACPVEVYDLMKLCWTYNVDDRPGFVAV 600 >sp|P15209|NTRK2_MOUSE BDNF/NT-3 growth factors receptor OS=Mus musculus OX=10090 GN=Ntrk2 PE=1 SV=1 Length=821 Score = 169 bits (428), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 109/295 (37%), Positives = 153/295 (52%), Gaps = 35/295 (12%) Query 893 HKRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 H LK R+LGEG FGKV L CY+ + +VAVK LK D R + +E ++L Sbjct 535 HNIVLK--RELGEGAFGKVFLAECYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELL 591 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------------IGL 997 L HEHI+K+ G C + L +V EY+ G L +L H + Sbjct 592 TNLQHEHIVKFYGVCVEG--DPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 649 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 +Q+L AQQI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV Sbjct 650 SQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV-YSTDYYRV 708 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 P+ W PE + KF SDVWS GV L+E+ T+ + P Sbjct 709 GGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTY---GKQP-----------WY 754 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 Q++ + E + +G L RP CP EVY LM CW+ E R +++ +L+ + Sbjct 755 QLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHTRKNIKSIHTLLQNL 809 Score = 87.4 bits (215), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 76/271 (28%), Positives = 120/271 (44%), Gaps = 41/271 (15%) Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 L P +D+ + V +K L + + F+ A L++ + H H+ +GVCV G IMV Sbjct 559 LCPEQDK---ILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMV 615 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMV---------------VAQQLASALSYLENKNLV 731 EY++HG L+ +L R H P A M +AQQ+A+ + YL +++ V Sbjct 616 FEYMKHGDLNKFL---RAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFV 672 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785 H ++ RN L+ G + +K+ D G+ S + + I W+ PE + Sbjct 673 HRDLATRNCLV-------GENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESI- 724 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LAT 843 +T D W G L EI G+ P S +E + L P +CPQ + Sbjct 725 -MYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYE 783 Query 844 LTSQCLTYEPTQR---PSFRTILRDLTRLQP 871 L C EP R S T+L++L + P Sbjct 784 LMLGCWQREPHTRKNIKSIHTLLQNLAKASP 814 >sp|P25911|LYN_MOUSE Tyrosine-protein kinase Lyn OS=Mus musculus OX=10090 GN=Lyn PE=1 SV=4 Length=512 Score = 164 bits (415), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 100/286 (35%), Positives = 152/286 (53%), Gaps = 28/286 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +K ++ LG G FG+V + Y N+ T VAVK LK G + +E ++++TL H Sbjct 247 IKLVKKLGAGQFGEVWMGYY---NNSTK--VAVKTLKP--GTMSVQAFLEEANLMKTLQH 299 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAY 1013 + +++ E+ + ++ E++ GSL D+L G L +L+ F+ QI EGMAY Sbjct 300 DKLVRLYAVV--TKEEPIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAY 357 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + ++YIHRDL A NVL+ + KI DFGLA+ + + Y RE P+ W APE + Sbjct 358 IERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAI 415 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 F SDVWSFG+ LYE++T+ I T + L +G R Sbjct 416 NFGCFTIKSDVWSFGILLYEIVTYGK--------------IPYPGRTNADVMSALSQGYR 461 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +PR + CP E+Y +MK CW+ +A RPTF+ L +L + +GQ Sbjct 462 MPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQ 507 Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 62/241 (26%), Positives = 115/241 (48%), Gaps = 23/241 (10%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P + AF E A+LM + H L ++ V + ++TE++ G L Sbjct 271 KVAVKTLKPGTMSVQ-AFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLD 329 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ + G + K++ + Q+A ++Y+E KN +H ++ N+L++ S K Sbjct 330 FLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSE-------SLMCK 382 Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 ++D G+ + E R I W APE + G ++ + D W FG L EI Sbjct 383 IADFGLAR-VIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKS--DVWSFGILLYEIVTY 439 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSF---RTILRD 865 G+ P R+ ++ + +R+P +CP +L + C + +RP+F +++L D Sbjct 440 GKIPYPGRTNADVMSALSQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDD 499 Query 866 L 866 Sbjct 500 F 500 >sp|P53356|HTK16_HYDVU Tyrosine-protein kinase HTK16 OS=Hydra vulgaris OX=6087 GN=HTK16 PE=2 SV=1 Length=757 Score = 168 bits (425), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 102/268 (38%), Positives = 143/268 (53%), Gaps = 22/268 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 ++LG G FG V + + G E+ VA+K L D Q + +E ++ L H I Sbjct 488 KELGVGEFGSVIKGIW--LSPGGKEINVAMKTLHKDKMVQGEKEFLREALVMSQLNHPCI 545 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + LV E V +G+L DYL + I L L+A QI GM YL + Sbjct 546 VSLLGVCLG---PPMILVQELVEMGALLDYLMDYQPEIQEVDLKLWASQIAFGMMYLELK 602 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 ++HRDLAARN+LL N + VKI DFGL++AV G +YY+ ++ G PV WYAPE + Sbjct 603 RFVHRDLAARNILLANKKQVKISDFGLSRAVGTGSDYYQAKQGGRWPVRWYAPESINYGT 662 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWS+G+TL+E+ T D + G+MT + LE RL +P Sbjct 663 FSTKSDVWSYGITLWEMFTFGD--------------LPYGEMTGNEVVSFLEHCGRLEKP 708 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165 D+CP Y +M +CW + + RPTF L Sbjct 709 DECPIHTYSIMLSCWHIDPNKRPTFNEL 736 Score = 90.9 bits (224), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 80/249 (32%), Positives = 120/249 (48%), Gaps = 29/249 (12%) Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALA----FYETASLMSQVSHTHLAFVHGVCVRGPE 682 L PG G+E+ V +K L H D + F A +MSQ++H + + GVC+ GP Sbjct 504 LSPG---GKEINVAMKTL---HKDKMVQGEKEFLREALVMSQLNHPCIVSLLGVCL-GPP 556 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 I+V E VE G L +L + + + A Q+A + YLE K VH ++ RNILL Sbjct 557 MILVQELVEMGALLDYLMDYQPEIQEVDLKLWASQIAFGMMYLELKRFVHRDLAARNILL 616 Query 743 ARLGLAEGTSPFIKLSDPG----VGLGA-LSREERVERIP--WLAPECLPGGANSLSTAM 795 A +K+SD G VG G+ + ++ R P W APE + G + ST Sbjct 617 A-------NKKQVKISDFGLSRAVGTGSDYYQAKQGGRWPVRWYAPESINYG--TFSTKS 667 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEP 853 D W +G TL E+ G+ P + +E F + RL +P CP ++ C +P Sbjct 668 DVWSYGITLWEMFTFGDLPYGEMTGNEVVSFLEHCGRLEKPDECPIHTYSIMLSCWHIDP 727 Query 854 TQRPSFRTI 862 +RP+F + Sbjct 728 NKRPTFNEL 736 >sp|Q91987|NTRK2_CHICK BDNF/NT-3 growth factors receptor OS=Gallus gallus OX=9031 GN=NTRK2 PE=1 SV=1 Length=818 Score = 168 bits (426), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 109/295 (37%), Positives = 152/295 (52%), Gaps = 35/295 (12%) Query 893 HKRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 H LK R+LGEG FGKV L CY+ + +VAVK LK D R + +E ++L Sbjct 532 HNIVLK--RELGEGAFGKVFLAECYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELL 588 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------------IGL 997 L HEHI+K+ G C + L +V EY+ G L +L H + Sbjct 589 TNLQHEHIVKFYGVCVEG--DPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNRPAELTQ 646 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 +Q+L AQQI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V +YYRV Sbjct 647 SQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV-YSTDYYRV 705 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 P+ W PE + KF SDVWS GV L+E+ T+ + P Sbjct 706 GGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTY---GKQP-----------WY 751 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 Q++ + E + +G L RP CP EVY LM CW+ E R + + +L+ + Sbjct 752 QLSNNEVIECITQGRVLQRPRTCPKEVYDLMLGCWQREPHMRLNIKEIHSLLQNL 806 Score = 84.3 bits (207), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 74/271 (27%), Positives = 120/271 (44%), Gaps = 41/271 (15%) Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 L P +D+ + V +K L + + F+ A L++ + H H+ +GVCV G IMV Sbjct 556 LCPEQDK---ILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMV 612 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMV---------------VAQQLASALSYLENKNLV 731 EY++HG L+ +L R H P A M +AQQ+A+ + YL +++ V Sbjct 613 FEYMKHGDLNKFL---RAHGPDAVLMAEGNRPAELTQSQMLHIAQQIAAGMVYLASQHFV 669 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLP 785 H ++ RN L+ G + +K+ D G+ S + + I W+ PE + Sbjct 670 HRDLATRNCLV-------GENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESI- 721 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLAT 843 +T D W G L EI G+ P S +E + L P +CP ++ Sbjct 722 -MYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPKEVYD 780 Query 844 LTSQCLTYEPTQRPSFRTI---LRDLTRLQP 871 L C EP R + + I L++L + P Sbjct 781 LMLGCWQREPHMRLNIKEIHSLLQNLAKASP 811 >sp|Q07014|LYN_RAT Tyrosine-protein kinase Lyn OS=Rattus norvegicus OX=10116 GN=Lyn PE=1 SV=3 Length=512 Score = 163 bits (413), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 99/286 (35%), Positives = 151/286 (53%), Gaps = 28/286 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +K ++ LG G FG+V + Y N+ T VAVK LK G + +E ++++TL H Sbjct 247 IKLVKKLGAGQFGEVWMGYY---NNSTK--VAVKTLKP--GTMSAQAFLEEANLMKTLQH 299 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAY 1013 + +++ E+ + ++ E++ GSL D+L + L +L+ F+ QI EGMAY Sbjct 300 DKLVRLYAVV--TKEEPIYIITEFMAKGSLLDFLKSDEGSKVLLPKLIDFSAQIAEGMAY 357 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + ++YIHRDL A NVL+ + KI DFGLA+ + + Y RE P+ W APE + Sbjct 358 IERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAI 415 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 F SDVWSFG+ LYE++T+ I T + L +G R Sbjct 416 NFGCFTIKSDVWSFGILLYEIVTYGK--------------IPYPGRTNADVMTALSQGYR 461 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +PR + CP E+Y +MK CW+ A RPTF+ L +L + +GQ Sbjct 462 MPRMENCPDELYDIMKMCWKESAEERPTFDYLQSVLDDFYTATEGQ 507 Score = 84.0 bits (206), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 63/241 (26%), Positives = 114/241 (47%), Gaps = 23/241 (10%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P A AF E A+LM + H L ++ V + ++TE++ G L Sbjct 271 KVAVKTLKPGTMS-AQAFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLD 329 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ + G + K++ + Q+A ++Y+E KN +H ++ N+L++ S K Sbjct 330 FLKSDEGSKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSE-------SLMCK 382 Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 ++D G+ + E R I W APE + G ++ + D W FG L EI Sbjct 383 IADFGLAR-VIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKS--DVWSFGILLYEIVTY 439 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSF---RTILRD 865 G+ P R+ ++ + +R+P +CP +L + C +RP+F +++L D Sbjct 440 GKIPYPGRTNADVMTALSQGYRMPRMENCPDELYDIMKMCWKESAEERPTFDYLQSVLDD 499 Query 866 L 866 Sbjct 500 F 500 >sp|Q95KR7|LCK_SAISC Proto-oncogene tyrosine-protein kinase LCK OS=Saimiri sciureus OX=9521 GN=LCK PE=1 SV=3 Length=509 Score = 163 bits (412), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 103/289 (36%), Positives = 150/289 (52%), Gaps = 29/289 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 + LK + LG G FG+V + Y N+ T VAVK+LK G + E ++++ Sbjct 242 RETLKLVERLGAGQFGEVWMGYY---NEHT--KVAVKSLKQ--GSMSPDAFLAEANLMKQ 294 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEG 1010 L H+ +++ E+ + ++ EY+ GSL D+L S + + +LL A QI EG Sbjct 295 LQHKRLVRLYAVVT---EEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIVEG 351 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 MA+L ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W AP Sbjct 352 MAFLEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKWTAP 409 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E + F SDVWSFG+ + E++TH I MT + + LER Sbjct 410 EAINYGTFTIKSDVWSFGILMTEIVTHGR--------------IPYPGMTNPEVIQNLER 455 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 G R+PRPD CP E+Y LM CW RPTF+ L +L+ +GQ Sbjct 456 GYRMPRPDNCPEELYKLMMQCWRERPDDRPTFDYLRSVLEDFFTATEGQ 504 Score = 85.1 bits (209), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 68/226 (30%), Positives = 108/226 (48%), Gaps = 25/226 (11%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 AF A+LM Q+ H L ++ V P I +TEY+E+G L +L+ G K++ Sbjct 284 AFLAEANLMKQLQHKRLVRLYAVVTEEPIYI-ITEYMENGSLVDFLKTPSGIKLTINKLL 342 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----- 767 +A Q+ +++LE +N +H ++ NIL++ + K++D GL L Sbjct 343 DMAAQIVEGMAFLEERNYIHRDLRAANILVS-------DTLSCKIAD--FGLARLIEDNE 393 Query 768 --SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 +RE I W APE + G ++ + D W FG + EI G P + E Sbjct 394 YTAREGAKFPIKWTAPEAINYGTFTIKS--DVWSFGILMTEIVTHGRIPYPGMTNPEVIQ 451 Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF---RTILRDL 866 +R +R+P P +CP +L L QC P RP+F R++L D Sbjct 452 NLERGYRMPRPDNCPEELYKLMMQCWRERPDDRPTFDYLRSVLEDF 497 >sp|P42679|MATK_HUMAN Megakaryocyte-associated tyrosine-protein kinase OS=Homo sapiens OX=9606 GN=MATK PE=1 SV=1 Length=507 Score = 163 bits (412), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 106/286 (37%), Positives = 153/286 (53%), Gaps = 37/286 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG V Y G+ VAVK +K D Q + E ++ + HE++++ Sbjct 241 IGEGEFGAVLQGEY------LGQKVAVKNIKCDVTAQ---AFLDETAVMTKMQHENLVRL 291 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 G QG L +VME+V G+L ++L R + AQLL F+ + EGM YL ++ Sbjct 292 LGVILHQG---LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKL 348 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDLAARN+L+ D + K+ DFGLAKA +G + R+ PV W APE LK KF Sbjct 349 VHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRL------PVKWTAPEALKHGKFT 402 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SDVWSFGV L+E+ ++ ++P K M++ ++E +E+G R+ P+ Sbjct 403 SKSDVWSFGVLLWEVFSY---GRAPYPK-----------MSLKEVSEAVEKGYRMEPPEG 448 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 CP V+ LM +CWE E + RP F L K E AP+ S Sbjct 449 CPGPVHVLMSSCWEAEPARRPPFRKLAE--KLARELRSAGAPASVS 492 Score = 87.4 bits (215), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 74/226 (33%), Positives = 109/226 (48%), Gaps = 24/226 (11%) Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAW 710 A AF + ++M+++ H +L + GV + I V E+V G L +LR R R V A Sbjct 270 AQAFLDETAVMTKMQHENLVRLLGVILHQGLYI-VMEHVSKGNLVNFLRTRGRALVNTAQ 328 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + + +A + YLE+K LVH ++ RNIL++ +A K+SD G L++ Sbjct 329 LLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVA-------KVSDFG-----LAKA 376 Query 771 ER----VERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 ER R+P W APE L G ++ D W FG L E+ G AP S E Sbjct 377 ERKGLDSSRLPVKWTAPEALKHG--KFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVS 434 Query 825 HFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTR 868 ++ +R+ P CP + L S C EP +RP FR + L R Sbjct 435 EAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLAR 480 >sp|Q61527|ERBB4_MOUSE Receptor tyrosine-protein kinase erbB-4 OS=Mus musculus OX=10090 GN=Erbb4 PE=1 SV=5 Length=1308 Score = 169 bits (428), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 108/305 (35%), Positives = 159/305 (52%), Gaps = 21/305 (7%) Query 864 RDLTRLQPHNLADVLTVNPDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922 R L R L + LT + +P + + + LK+++ LG G FG V + P + Sbjct 684 RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGET 743 Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982 VA+K L GP+ + E I+ ++ H H+++ G C ++QLV + +P Sbjct 744 VKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCL---SPTIQLVTQLMP 800 Query 983 LGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040 G L DY+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI Sbjct 801 HGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKIT 860 Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100 DFGLA+ + EG E + G P+ W A EC+ KF + SDVWS+GVT++EL+T Sbjct 861 DFGLARLL-EGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMT---- 915 Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 G + + +LLE+GERLP+P C +VY +M CW +A RP Sbjct 916 ----------FGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRP 965 Query 1161 TFENL 1165 F+ L Sbjct 966 KFKEL 970 Score = 76.6 bits (187), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 69/302 (23%), Positives = 129/302 (43%), Gaps = 39/302 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 +Q + + E+ ++ LG G VY+G EG E +P Sbjct 706 NQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEG-----------ETVKIP------- 747 Query 637 LRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K+L+ + A + F + A +M+ + H HL + GVC+ P +VT+ + HG L Sbjct 748 --VAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCL-SPTIQLVTQLMPHGCL 804 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 ++ + ++ + Q+A + YLE + LVH ++ RN+L+ + + Sbjct 805 LDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVK-------SPNHV 857 Query 756 KLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 K++D G+ L +E + I W+A EC+ + D W +G T+ E+ Sbjct 858 KITDFGLARLLEGDEKEYNADGGKMPIKWMALECI--HYRKFTHQSDVWSYGVTIWELMT 915 Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLT 867 G P E ++ RLP+P + + +C + RP F+ + + + Sbjct 916 FGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFS 975 Query 868 RL 869 R+ Sbjct 976 RM 977 >sp|Q5PXS1|LCK_AOTNA Tyrosine-protein kinase Lck OS=Aotus nancymaae OX=37293 GN=LCK PE=2 SV=4 Length=509 Score = 162 bits (411), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 103/289 (36%), Positives = 151/289 (52%), Gaps = 29/289 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 + LK + LG G FG+V + Y ND T VAVK+LK G + E ++++ Sbjct 242 RETLKLVERLGAGQFGEVWMGYY---NDHT--KVAVKSLKQ--GSMSPDAFLAEANLMKQ 294 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEG 1010 L H+ +++ ++ + ++ EY+ GSL D+L S + + +LL A QI EG Sbjct 295 LQHQRLVRLYAVVT---QEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEG 351 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 MA++ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W AP Sbjct 352 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKWTAP 409 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E + F SDVWSFG+ L E++TH I MT + + LER Sbjct 410 EAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQNLER 455 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 G R+ RPD CP E+YHLM CW+ RPTF+ L +L+ +GQ Sbjct 456 GYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLEDFFTATEGQ 504 Score = 80.1 bits (196), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 67/226 (30%), Positives = 108/226 (48%), Gaps = 25/226 (11%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 AF A+LM Q+ H L ++ V + P I +TEY+E+G L +L+ G K++ Sbjct 284 AFLAEANLMKQLQHQRLVRLYAVVTQEPIYI-ITEYMENGSLVDFLKTPSGIKLTINKLL 342 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----- 767 +A Q+A ++++E +N +H ++ NIL++ + K++D GL L Sbjct 343 DMAAQIAEGMAFIEERNYIHRDLRAANILVS-------DTLSCKIAD--FGLARLIEDNE 393 Query 768 --SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 +RE I W APE + G ++ + D W FG L EI G P + E Sbjct 394 YTAREGAKFPIKWTAPEAINYGTFTIKS--DVWSFGILLTEIVTHGRIPYPGMTNPEVIQ 451 Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF---RTILRDL 866 +R +R+ P +CP +L L C P RP+F R++L D Sbjct 452 NLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLEDF 497 >sp|Q14289|FAK2_HUMAN Protein-tyrosine kinase 2-beta OS=Homo sapiens OX=9606 GN=PTK2B PE=1 SV=2 Length=1009 Score = 168 bits (426), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 103/279 (37%), Positives = 154/279 (55%), Gaps = 28/279 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LGEG FG+V Y + G VAVK K DC ++ + E I++ L H HI+ Sbjct 429 RILGEGFFGEVYEGVYT-NHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIV 487 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQH 1018 K G E E+ ++ME P G L YL R+ S+ + L+L++ QIC+ MAYL + + Sbjct 488 KLIGIIE---EEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESIN 544 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRD+A RN+L+ + VK+GDFGL++ + E +YY+ P+ W +PE + +F Sbjct 545 CVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKA-SVTRLPIKWMSPESINFRRF 602 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE---LIGIAQGQMTVLRLTELLERGERLP 1135 ASDVW F V ++E+L+ P +LE +IG+ LE+G+RLP Sbjct 603 TTASDVWMFAVCMWEILSFGKQ----PFFWLENKDVIGV-------------LEKGDRLP 645 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 +PD CP +Y LM CW+ + S RP F L+ L V++ Sbjct 646 KPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQ 684 Score = 84.0 bits (206), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 66/245 (27%), Positives = 113/245 (46%), Gaps = 22/245 (9%) Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +G+++ V +K D F A +M + H H+ + G+ P I + E Sbjct 448 KGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWI-IMELYP 506 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 +G L +L R + + + ++ + Q+ A++YLE+ N VH ++ RNIL+A + Sbjct 507 YGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVA-------S 559 Query 752 SPFIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATL 804 +KL D GL +E V R+P W++PE + +TA D W F + Sbjct 560 PECVKLGD--FGLSRYIEDEDYYKASVTRLPIKWMSPESI--NFRRFTTASDVWMFAVCM 615 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC--PQLATLTSQCLTYEPTQRPSFRTI 862 EI G+ P + ++ RLP+P P L TL ++C Y+P+ RP F + Sbjct 616 WEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTEL 675 Query 863 LRDLT 867 + L+ Sbjct 676 VCSLS 680 >sp|P41241|CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus musculus OX=10090 GN=Csk PE=1 SV=2 Length=450 Score = 161 bits (407), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 100/278 (36%), Positives = 146/278 (53%), Gaps = 35/278 (13%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 + + LK ++ +G+G FG V L D G VAVK +K D Q + E ++ Sbjct 190 LNMKELKLLQTIGKGEFGDVML------GDYRGNKVAVKCIKNDATAQ---AFLAEASVM 240 Query 952 RTLYHEHIIKYKGC-CEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQI 1007 L H ++++ G E++G L +V EY+ GSL DYL R +G LL F+ + Sbjct 241 TQLRHSNLVQLLGVIVEEKG--GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDV 298 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 CE M YL +++HRDLAARNVL+ D + K+ DFGL K E ++ G PV W Sbjct 299 CEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------EASSTQDTGKLPVKW 352 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE L+E KF SDVWSFG+ L+E+ + + ++ + + Sbjct 353 TAPEALREKKFSTKSDVWSFGILLWEIYSFGR--------------VPYPRIPLKDVVPR 398 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 +E+G ++ PD CP VY +MKNCW +A+ RPTF L Sbjct 399 VEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPTFLQL 436 Score = 78.2 bits (191), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 66/231 (29%), Positives = 106/231 (46%), Gaps = 20/231 (9%) Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLR-RERGHVPMA 709 A AF AS+M+Q+ H++L + GV V + +VTEY+ G L +LR R R + Sbjct 230 AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD 289 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 + + + A+ YLE N VH ++ RN+L++ +A K+SD G+ A S Sbjct 290 CLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVA-------KVSDFGLTKEASST 342 Query 770 EERVER-IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA-----PLQSRSPSEK 823 ++ + + W APE L ST D W FG L EI G PL+ P + Sbjct 343 QDTGKLPVKWTAPEALR--EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVE 400 Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 + + + P+ P + + C + RP+F + L ++ H L Sbjct 401 KGY---KMDAPDGCPPAVYEVMKNCWHLDAATRPTFLQLREQLEHIKTHEL 448 >sp|P32577|CSK_RAT Tyrosine-protein kinase CSK OS=Rattus norvegicus OX=10116 GN=Csk PE=1 SV=1 Length=450 Score = 161 bits (407), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 100/278 (36%), Positives = 146/278 (53%), Gaps = 35/278 (13%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 + + LK ++ +G+G FG V L D G VAVK +K D Q + E ++ Sbjct 190 LNMKELKLLQTIGKGEFGDVML------GDYRGNKVAVKCIKNDATAQ---AFLAEASVM 240 Query 952 RTLYHEHIIKYKGC-CEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQI 1007 L H ++++ G E++G L +V EY+ GSL DYL R +G LL F+ + Sbjct 241 TQLRHSNLVQLLGVIVEEKG--GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDV 298 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 CE M YL +++HRDLAARNVL+ D + K+ DFGL K E ++ G PV W Sbjct 299 CEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------EASSTQDTGKLPVKW 352 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE L+E KF SDVWSFG+ L+E+ + + ++ + + Sbjct 353 TAPEALREKKFSTKSDVWSFGILLWEIYSFGR--------------VPYPRIPLKDVVPR 398 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 +E+G ++ PD CP VY +MKNCW +A+ RPTF L Sbjct 399 VEKGYKMDAPDGCPPAVYDVMKNCWHLDAATRPTFLQL 436 Score = 78.2 bits (191), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 66/231 (29%), Positives = 106/231 (46%), Gaps = 20/231 (9%) Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLR-RERGHVPMA 709 A AF AS+M+Q+ H++L + GV V + +VTEY+ G L +LR R R + Sbjct 230 AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD 289 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 + + + A+ YLE N VH ++ RN+L++ +A K+SD G+ A S Sbjct 290 CLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVA-------KVSDFGLTKEASST 342 Query 770 EERVER-IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA-----PLQSRSPSEK 823 ++ + + W APE L ST D W FG L EI G PL+ P + Sbjct 343 QDTGKLPVKWTAPEALR--EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVE 400 Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 + + + P+ P + + C + RP+F + L ++ H L Sbjct 401 KGY---KMDAPDGCPPAVYDVMKNCWHLDAATRPTFLQLREQLEHIRTHEL 448 >sp|P04629|NTRK1_HUMAN High affinity nerve growth factor receptor OS=Homo sapiens OX=9606 GN=NTRK1 PE=1 SV=4 Length=796 Score = 167 bits (422), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 110/319 (34%), Positives = 160/319 (50%), Gaps = 46/319 (14%) Query 887 SDPTVFH--KRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSG 943 SD V H +R + +LGEG FGKV L C++ + +VAVKALK + R Sbjct 498 SDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALK-EASESARQD 556 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------- 994 +++E ++L L H+HI+++ G C + + L +V EY+ G L +L H Sbjct 557 FQREAELLTMLQHQHIVRFFGVCTEG--RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGG 614 Query 995 -------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 +GL QLL A Q+ GM YL H++HRDLA RN L+ +VKIGDFG+++ Sbjct 615 EDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRD 674 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + +YYRV P+ W PE + KF SDVWSFGV L+E+ T+ Sbjct 675 I-YSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY---- 729 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 Q++ + + +G L RP CP EVY +M+ CW+ E R + Sbjct 730 ----------QLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHS------ 773 Query 1168 ILKTVHEKYQ--GQAPSVF 1184 +K VH + Q QAP V+ Sbjct 774 -IKDVHARLQALAQAPPVY 791 Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 74/309 (24%), Positives = 123/309 (40%), Gaps = 50/309 (16%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 S H + +++I LG+G V+ + + L+P +D+ Sbjct 497 FSDACVHHIKRRDIVLKWELGEGAFGKVF----------------LAECHNLLPEQDK-- 538 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 + V +K L + F A L++ + H H+ GVC G +MV EY+ HG L Sbjct 539 -MLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDL 597 Query 696 DVWLRRER--------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 + +LR G + + + VA Q+A+ + YL + VH ++ RN L Sbjct 598 NRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCL 657 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAM 795 + G +K+ D G+ S + + I W+ PE + +T Sbjct 658 V-------GQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESIL--YRKFTTES 708 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEP 853 D W FG L EI G+ P S +E + L P +C P++ + C EP Sbjct 709 DVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREP 768 Query 854 TQRPSFRTI 862 QR S + + Sbjct 769 QQRHSIKDV 777 >sp|P41242|MATK_MOUSE Megakaryocyte-associated tyrosine-protein kinase OS=Mus musculus OX=10090 GN=Matk PE=1 SV=2 Length=505 Score = 162 bits (409), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 100/270 (37%), Positives = 147/270 (54%), Gaps = 35/270 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG V Y G+ VAVK +K D Q + E ++ L H ++++ Sbjct 239 IGEGEFGAVLQGEY------LGQKVAVKNIKCDVTAQ---AFLDETAVMTKLQHRNLVRL 289 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 G G L +VME+V G+L ++L R + +QLL FA + EGM YL ++ Sbjct 290 LGVILHHG---LYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKL 346 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDLAARN+L+ D + K+ DFGLAKA +G + R+ PV W APE LK +F Sbjct 347 VHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRL------PVKWTAPEALKNGRFS 400 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SDVWSFGV L+E+ ++ ++P K M++ ++E +E+G R+ PD Sbjct 401 SKSDVWSFGVLLWEVFSY---GRAPYPK-----------MSLKEVSEAVEKGYRMEPPDG 446 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 CP V+ LM +CWE E + RP F ++ L Sbjct 447 CPGSVHTLMGSCWEAEPARRPPFRKIVEKL 476 Score = 91.3 bits (225), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 76/226 (34%), Positives = 110/226 (49%), Gaps = 24/226 (11%) Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAW 710 A AF + ++M+++ H +L + GV + I V E+V G L +LR R R V + Sbjct 268 AQAFLDETAVMTKLQHRNLVRLLGVILHHGLYI-VMEHVSKGNLVNFLRTRGRALVSTSQ 326 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + A +A + YLE+K LVH ++ RNIL++ +A K+SD G L++ Sbjct 327 LLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVA-------KVSDFG-----LAKA 374 Query 771 ER----VERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 ER R+P W APE L G S+ D W FG L E+ G AP S E Sbjct 375 ERKGLDSSRLPVKWTAPEALKNG--RFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVS 432 Query 825 HFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTR 868 ++ +R+ P CP + TL C EP +RP FR I+ L R Sbjct 433 EAVEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRKIVEKLGR 478 >sp|Q16288|NTRK3_HUMAN NT-3 growth factor receptor OS=Homo sapiens OX=9606 GN=NTRK3 PE=1 SV=2 Length=839 Score = 166 bits (421), Expect = 7e-41, Method: Compositional matrix adjust. Identities = 113/302 (37%), Positives = 155/302 (51%), Gaps = 52/302 (17%) Query 901 RDLGEGHFGKVSLY-CYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 R+LGEG FGKV L CY+ PT D +VAVKALK D R +++E ++L L HE Sbjct 542 RELGEGAFGKVFLAECYNLSPTKDKM--LVAVKALK-DPTLAARKDFQREAELLTNLQHE 598 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQL 1000 HI+K+ G C D L +V EY+ G L +L H +GL+Q+ Sbjct 599 HIVKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQM 656 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV----------PE 1050 L A QI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V P Sbjct 657 LHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRLFNPS 716 Query 1051 GHEYYRVREDGDS---PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 G+++ E G P+ W PE + KF SDVWSFGV L+E+ T+ + P Sbjct 717 GNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTY---GKQP--- 770 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 Q++ + E + +G L RP CP EVY +M CW+ E R + + Sbjct 771 --------WFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYK 822 Query 1168 IL 1169 IL Sbjct 823 IL 824 Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 70/280 (25%), Positives = 116/280 (41%), Gaps = 49/280 (18%) Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 L P +D+ + V +K L F A L++ + H H+ +GVC G IMV Sbjct 560 LSPTKDK---MLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMV 616 Query 687 TEYVEHGPLDVWL---------------RRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 EY++HG L+ +L R+ +G + ++ + +A Q+AS + YL +++ V Sbjct 617 FEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFV 676 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE--------------------E 771 H ++ RN L+ G + +K+ D G+ S + Sbjct 677 HRDLATRNCLV-------GANLLVKIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGH 729 Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 + I W+ PE + +T D W FG L EI G+ P S +E + Sbjct 730 TMLPIRWMPPESI--MYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGR 787 Query 832 RLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 L P CP ++ + C EP QR + + I + L L Sbjct 788 VLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 827 >sp|P41240|CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo sapiens OX=9606 GN=CSK PE=1 SV=1 Length=450 Score = 160 bits (405), Expect = 7e-41, Method: Compositional matrix adjust. Identities = 99/278 (36%), Positives = 146/278 (53%), Gaps = 35/278 (13%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 + + LK ++ +G+G FG V L D G VAVK +K D Q + E ++ Sbjct 190 LNMKELKLLQTIGKGEFGDVML------GDYRGNKVAVKCIKNDATAQ---AFLAEASVM 240 Query 952 RTLYHEHIIKYKGC-CEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQI 1007 L H ++++ G E++G L +V EY+ GSL DYL R +G LL F+ + Sbjct 241 TQLRHSNLVQLLGVIVEEKG--GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDV 298 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 CE M YL +++HRDLAARNVL+ D + K+ DFGL K E ++ G PV W Sbjct 299 CEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------EASSTQDTGKLPVKW 352 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE L+E KF SDVWSFG+ L+E+ + + ++ + + Sbjct 353 TAPEALREKKFSTKSDVWSFGILLWEIYSFGR--------------VPYPRIPLKDVVPR 398 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 +E+G ++ PD CP VY +MKNCW +A+ RP+F L Sbjct 399 VEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQL 436 Score = 79.3 bits (194), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 67/231 (29%), Positives = 106/231 (46%), Gaps = 20/231 (9%) Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLR-RERGHVPMA 709 A AF AS+M+Q+ H++L + GV V + +VTEY+ G L +LR R R + Sbjct 230 AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGD 289 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 + + + A+ YLE N VH ++ RN+L++ +A K+SD G+ A S Sbjct 290 CLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVA-------KVSDFGLTKEASST 342 Query 770 EERVER-IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA-----PLQSRSPSEK 823 ++ + + W APE L ST D W FG L EI G PL+ P + Sbjct 343 QDTGKLPVKWTAPEALR--EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVE 400 Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 + + + P+ P + + C + RPSF + L ++ H L Sbjct 401 KGY---KMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTHEL 448 >sp|P70600|FAK2_RAT Protein-tyrosine kinase 2-beta OS=Rattus norvegicus OX=10116 GN=Ptk2b PE=1 SV=1 Length=1009 Score = 167 bits (423), Expect = 8e-41, Method: Compositional matrix adjust. Identities = 104/279 (37%), Positives = 154/279 (55%), Gaps = 28/279 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LGEG FG+V Y + G VAVK K DC ++ + E I++ L H HI+ Sbjct 429 RILGEGFFGEVYEGVYT-NHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIV 487 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQH 1018 K G E E+ +VME P G L YL R+ S+ + L+L+A QIC+ MAYL + + Sbjct 488 KLIGIIE---EEPTWIVMELYPYGELGHYLERNKNSLKVPTLVLYALQICKAMAYLESIN 544 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRD+A RN+L+ + VK+GDFGL++ + E +YY+ P+ W +PE + +F Sbjct 545 CVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKA-SVTRLPIKWMSPESINFRRF 602 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE---LIGIAQGQMTVLRLTELLERGERLP 1135 ASDVW F V ++E+L S P +LE +IG+ LE+G+RLP Sbjct 603 TTASDVWMFAVCMWEIL----SFGKQPFFWLENKDVIGV-------------LEKGDRLP 645 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 +P+ CP +Y LM CW+ + S RP F L+ L +++ Sbjct 646 KPELCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDIYQ 684 Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 68/247 (28%), Positives = 114/247 (46%), Gaps = 22/247 (9%) Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +G+++ V +K D F A +M + H H+ + G+ P I V E Sbjct 448 KGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWI-VMELYP 506 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 +G L +L R + + + ++ A Q+ A++YLE+ N VH ++ RNIL+A + Sbjct 507 YGELGHYLERNKNSLKVPTLVLYALQICKAMAYLESINCVHRDIAVRNILVA-------S 559 Query 752 SPFIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATL 804 +KL D GL +E V R+P W++PE + +TA D W F + Sbjct 560 PECVKLGD--FGLSRYIEDEDYYKASVTRLPIKWMSPESI--NFRRFTTASDVWMFAVCM 615 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC--PQLATLTSQCLTYEPTQRPSFRTI 862 EI G+ P + ++ RLP+P P L TL ++C Y+P+ RP F + Sbjct 616 WEILSFGKQPFFWLENKDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDYDPSDRPRFTEL 675 Query 863 LRDLTRL 869 + L+ + Sbjct 676 VCSLSDI 682 >sp|Q0VBZ0|CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos taurus OX=9913 GN=CSK PE=2 SV=1 Length=450 Score = 160 bits (404), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 97/272 (36%), Positives = 143/272 (53%), Gaps = 33/272 (12%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 LK ++ +G+G FG V L D G VAVK +K D Q + E ++ L H Sbjct 195 LKLLQTIGKGEFGDVML------GDYRGNKVAVKCIKNDATAQ---AFLAEASVMTQLRH 245 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAY 1013 ++++ G ++ + L +V EY+ GSL DYL R +G LL F+ +CE M Y Sbjct 246 SNLVQLLGVIVEE-KSGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEY 304 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 L +++HRDLAARNVL+ D + K+ DFGL K E ++ G PV W APE L Sbjct 305 LEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK------EASSTQDTGKLPVKWTAPEAL 358 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +E KF SDVWSFG+ L+E+ + + ++ + + +E+G + Sbjct 359 REKKFSTKSDVWSFGILLWEIYSFGR--------------VPYPRIPLKDVVPRVEKGYK 404 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + PD CP VY +MKNCW +A+ RP+F L Sbjct 405 MDAPDGCPPAVYEVMKNCWHLDAATRPSFLQL 436 Score = 82.4 bits (202), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 68/231 (29%), Positives = 107/231 (46%), Gaps = 20/231 (9%) Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLR-RERGHVPMA 709 A AF AS+M+Q+ H++L + GV V + +VTEY+ G L +LR R R + Sbjct 230 AQAFLAEASVMTQLRHSNLVQLLGVIVEEKSGLYIVTEYMAKGSLVDYLRSRGRSVLGGD 289 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 + + + A+ YLE N VH ++ RN+L++ +A K+SD G+ A S Sbjct 290 CLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVA-------KVSDFGLTKEASST 342 Query 770 EERVER-IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA-----PLQSRSPSEK 823 ++ + + W APE L ST D W FG L EI G PL+ P + Sbjct 343 QDTGKLPVKWTAPEALR--EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVE 400 Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 + + + P+ P + + C + RPSF + L R++ H L Sbjct 401 KGY---KMDAPDGCPPAVYEVMKNCWHLDAATRPSFLQLREQLERIKTHEL 448 >sp|Q15303|ERBB4_HUMAN Receptor tyrosine-protein kinase erbB-4 OS=Homo sapiens OX=9606 GN=ERBB4 PE=1 SV=1 Length=1308 Score = 167 bits (423), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 107/305 (35%), Positives = 159/305 (52%), Gaps = 21/305 (7%) Query 864 RDLTRLQPHNLADVLTVNPDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922 R L R L + LT + +P + + + LK+++ LG G FG V + P + Sbjct 684 RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGET 743 Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982 VA+K L GP+ + E I+ ++ H H+++ G C ++QLV + +P Sbjct 744 VKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCL---SPTIQLVTQLMP 800 Query 983 LGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040 G L +Y+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI Sbjct 801 HGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKIT 860 Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100 DFGLA+ + EG E + G P+ W A EC+ KF + SDVWS+GVT++EL+T Sbjct 861 DFGLARLL-EGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMT---- 915 Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 G + + +LLE+GERLP+P C +VY +M CW +A RP Sbjct 916 ----------FGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRP 965 Query 1161 TFENL 1165 F+ L Sbjct 966 KFKEL 970 Score = 76.6 bits (187), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 70/309 (23%), Positives = 131/309 (42%), Gaps = 39/309 (13%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P +Q + + E+ ++ LG G VY+G EG E +P Sbjct 699 TPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEG-----------ETVKIP 747 Query 630 GRDRGQELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 V +K+L+ + A + F + A +M+ + H HL + GVC+ P +VT+ Sbjct 748 ---------VAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCL-SPTIQLVTQ 797 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + HG L ++ + ++ + Q+A + YLE + LVH ++ RN+L+ Sbjct 798 LMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVK----- 852 Query 749 EGTSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGA 802 + +K++D G+ L +E + I W+A EC+ + D W +G Sbjct 853 --SPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECI--HYRKFTHQSDVWSYGV 908 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFR 860 T+ E+ G P E ++ RLP+P + + +C + RP F+ Sbjct 909 TIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFK 968 Query 861 TILRDLTRL 869 + + +R+ Sbjct 969 ELAAEFSRM 977 >sp|P06240|LCK_MOUSE Proto-oncogene tyrosine-protein kinase LCK OS=Mus musculus OX=10090 GN=Lck PE=1 SV=4 Length=509 Score = 160 bits (406), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 101/289 (35%), Positives = 147/289 (51%), Gaps = 29/289 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 + LK + LG G FG+V + Y+ VAVK+LK G + E ++++ Sbjct 242 RETLKLVERLGAGQFGEVWMGYYNGHTK-----VAVKSLKQ--GSMSPDAFLAEANLMKQ 294 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEG 1010 L H +++ ++ + ++ EY+ GSL D+L S + + +LL A QI EG Sbjct 295 LQHPRLVRLYAVVT---QEPIYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQIAEG 351 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 MA++ Q+YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W AP Sbjct 352 MAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKWTAP 409 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E + F SDVWSFG+ L E++TH I MT + + LER Sbjct 410 EAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQNLER 455 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 G R+ RPD CP E+YHLM CW+ RPTF+ L +L +GQ Sbjct 456 GYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLDDFFTATEGQ 504 Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 67/226 (30%), Positives = 108/226 (48%), Gaps = 25/226 (11%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 AF A+LM Q+ H L ++ V + P I +TEY+E+G L +L+ G K++ Sbjct 284 AFLAEANLMKQLQHPRLVRLYAVVTQEPIYI-ITEYMENGSLVDFLKTPSGIKLNVNKLL 342 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----- 767 +A Q+A ++++E +N +H ++ NIL++ + K++D GL L Sbjct 343 DMAAQIAEGMAFIEEQNYIHRDLRAANILVS-------DTLSCKIAD--FGLARLIEDNE 393 Query 768 --SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 +RE I W APE + G ++ + D W FG L EI G P + E Sbjct 394 YTAREGAKFPIKWTAPEAINYGTFTIKS--DVWSFGILLTEIVTHGRIPYPGMTNPEVIQ 451 Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF---RTILRDL 866 +R +R+ P +CP +L L C P RP+F R++L D Sbjct 452 NLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLDDF 497 >sp|P42689|SRK3_SPOLA Tyrosine-protein kinase SRK3 (Fragment) OS=Spongilla lacustris OX=6055 GN=SRK3 PE=2 SV=1 Length=334 Score = 156 bits (394), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 97/276 (35%), Positives = 148/276 (54%), Gaps = 28/276 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LG+G+FG+V ++ T VAVK LK D + QE +++ ++H +++ Sbjct 70 RKLGQGNFGEVWAGVWNGTT-----AVAVKTLKPDT--MEVKDFVQEAQVMKKIHHPNLL 122 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQ 1017 + C GE + +V E + GS+ +YL +I L Q++ + QI GM YL A Sbjct 123 QLYAVCT-IGE-PIYIVTELMKYGSMLEYLKHGEGKNITLHQMVDMSAQIASGMTYLEAH 180 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 YIHRDLAARN+L+ + K+ DFGLA+ + E + Y RE P+ W APE + Sbjct 181 SYIHRDLAARNILVGEGNVCKVADFGLARVIKE--DIYNPREGTKFPIKWTAPEAALYNR 238 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFGV + E++TH + MT ++ E ++RG R+P P Sbjct 239 FTIKSDVWSFGVLISEIVTHGR--------------MPYPGMTNRQVLEAVDRGYRMPCP 284 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + CP +Y +M +CW+ E RPTFE+L +L+ + Sbjct 285 EGCPDPLYKIMLSCWKHEPDDRPTFESLKNLLEDYY 320 Score = 86.3 bits (212), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 64/234 (27%), Positives = 108/234 (46%), Gaps = 22/234 (9%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K L P ++ F + A +M ++ H +L ++ VC G +VTE +++G + + Sbjct 91 VAVKTLKPDTMEVK-DFVQEAQVMKKIHHPNLLQLYAVCTIGEPIYIVTELMKYGSMLEY 149 Query 699 LRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 L+ G +MV ++ Q+AS ++YLE + +H ++ RNIL+ G K+ Sbjct 150 LKHGEGKNITLHQMVDMSAQIASGMTYLEAHSYIHRDLAARNILV-------GEGNVCKV 202 Query 758 SDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +D GL + +E+ I W APE N + D W FG + EI Sbjct 203 AD--FGLARVIKEDIYNPREGTKFPIKWTAPEA--ALYNRFTIKSDVWSFGVLISEIVTH 258 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 G P + + R +R+P P CP L + C +EP RP+F ++ Sbjct 259 GRMPYPGMTNRQVLEAVDRGYRMPCPEGCPDPLYKIMLSCWKHEPDDRPTFESL 312 >sp|P11273|ERBB_AVIEU Tyrosine-protein kinase transforming protein erbB OS=Avian erythroblastosis virus (strain ts167) OX=103898 GN=V-ERBB PE=3 SV=1 Length=540 Score = 161 bits (408), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 107/307 (35%), Positives = 161/307 (52%), Gaps = 22/307 (7%) Query 864 RDLTRL-QPHNLADVLTVNPDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 R L RL Q L + LT + ++P + + + KK++ LG G FG V + P + Sbjct 97 RTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKVKVLGFGAFGTVYKGLWIPEGE 156 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VA+K L+ P+ E ++ ++ + H+ + G C ++QL+ + + Sbjct 157 KVTIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS---TVQLITQLM 213 Query 982 PLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P G L DY+ H +IG LL + QI +GM YL +H +HRDLAARNVL+ + VKI Sbjct 214 PYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERHMVHRDLAARNVLVKTPQHVKI 273 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLAK + + Y E G P+ W A E + + + SDVWS+GVT++EL+T Sbjct 274 TDFGLAKQLGADEKEYHA-EGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTF-- 330 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 S P GI + ++ +LE+GERLP+P C +VY +M CW ++A R Sbjct 331 --GSKPYD-----GIPASE-----ISSVLEKGERLPQPPICTIDVYMIMVKCWMSDADSR 378 Query 1160 PTFENLI 1166 P F LI Sbjct 379 PKFRELI 385 Score = 73.9 bits (180), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 51/221 (23%), Positives = 108/221 (49%), Gaps = 18/221 (8%) Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 + A +M+ V + H+ + G+C+ ++T+ + +G L ++R + ++ + + Sbjct 181 DEAYVMASVDNPHVCRLLGICLTSTVQ-LITQLMPYGCLLDYIREHKDNIGSQYLLNWCV 239 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE 774 Q+A ++YLE +++VH ++ RN+L+ T +K++D G+ LGA +E E Sbjct 240 QIAKGMNYLEERHMVHRDLAARNVLVK-------TPQHVKITDFGLAKQLGADEKEYHAE 292 Query 775 --RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 ++P W+A E + + + D W +G T+ E+ G P SE ++ Sbjct 293 GGKVPIKWMALESILHRIYTHQS--DVWSYGVTVWELMTFGSKPYDGIPASEISSVLEKG 350 Query 831 HRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869 RLP+P + + +C + RP FR ++ + +++ Sbjct 351 ERLPQPPICTIDVYMIMVKCWMSDADSRPKFRELIAEFSKM 391 >sp|P41243|MATK_RAT Megakaryocyte-associated tyrosine-protein kinase OS=Rattus norvegicus OX=10116 GN=Matk PE=2 SV=1 Length=467 Score = 160 bits (404), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 100/270 (37%), Positives = 145/270 (54%), Gaps = 34/270 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG V Y G+ VAVK +K D Q + E ++ L H ++++ Sbjct 200 IGEGEFGAVLQGEY------LGQKVAVKNIKCDVTAQ---AFLDETAVMTKLQHRNLVRL 250 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 G G L +VME+V G+L ++L R + +QLL FA + EGM YL ++ Sbjct 251 LGVILHHG---LYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKL 307 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDLAARN+L+ D + K+ DFGLAKA E + + PV W APE LK +F Sbjct 308 VHRDLAARNILVSEDLVAKVSDFGLAKA-----ELRKGLDSSRLPVKWTAPEALKNGRFS 362 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SDVWSFGV L+E+ ++ ++P K M++ ++E +E+G R+ PD Sbjct 363 SKSDVWSFGVLLWEVFSY---GRAPYPK-----------MSLKEVSEAVEKGYRMEPPDS 408 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 CP V+ LM +CWE E S RP F ++ L Sbjct 409 CPGPVHTLMGSCWEAEPSRRPPFRKIVEKL 438 Score = 97.1 bits (240), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 75/222 (34%), Positives = 110/222 (50%), Gaps = 15/222 (7%) Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAW 710 A AF + ++M+++ H +L + GV + I V E+V G L +LR R R V + Sbjct 229 AQAFLDETAVMTKLQHRNLVRLLGVILHHGLYI-VMEHVSKGNLVNFLRTRGRALVSTSQ 287 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + A +A + YLE+K LVH ++ RNIL++ +A K+SD G+ L + Sbjct 288 LLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVA-------KVSDFGLAKAELRKG 340 Query 771 ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 R+P W APE L G S+ D W FG L E+ G AP S E + Sbjct 341 LDSSRLPVKWTAPEALKNG--RFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVE 398 Query 829 RQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTR 868 + +R+ P SCP + TL C EP++RP FR I+ L R Sbjct 399 KGYRMEPPDSCPGPVHTLMGSCWEAEPSRRPPFRKIVEKLGR 440 >sp|Q9QVP9|FAK2_MOUSE Protein-tyrosine kinase 2-beta OS=Mus musculus OX=10090 GN=Ptk2b PE=1 SV=2 Length=1009 Score = 166 bits (420), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 102/279 (37%), Positives = 153/279 (55%), Gaps = 28/279 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LGEG FG+V Y + G VAVK K DC ++ + E I++ L H HI+ Sbjct 429 RILGEGFFGEVYEGVYT-NHKGEKINVAVKTCKKDCTQDNKEKFMSEAVIMKNLDHPHIV 487 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQH 1018 K G E E+ ++ME P G L YL R+ S+ + L+L+ QIC+ MAYL + + Sbjct 488 KLIGIIE---EEPTWIIMELYPYGELGHYLERNKNSLKVPTLVLYTLQICKAMAYLESIN 544 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRD+A RN+L+ + VK+GDFGL++ + E +YY+ P+ W +PE + +F Sbjct 545 CVHRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKA-SVTRLPIKWMSPESINFRRF 602 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE---LIGIAQGQMTVLRLTELLERGERLP 1135 ASDVW F V ++E+L S P +LE +IG+ LE+G+RLP Sbjct 603 TTASDVWMFAVCMWEIL----SFGKQPFFWLENKDVIGV-------------LEKGDRLP 645 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 +P+ CP +Y LM CW+ + S RP F L+ L +++ Sbjct 646 KPELCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDIYQ 684 Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 76/296 (26%), Positives = 127/296 (43%), Gaps = 43/296 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V ++E+ LG+G VYEG V +G+++ V +K Sbjct 420 VAREEVVLNRILGEGFFGEVYEG---------------------VYTNHKGEKINVAVKT 458 Query 644 LDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 D F A +M + H H+ + G+ P I + E +G L +L R Sbjct 459 CKKDCTQDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWI-IMELYPYGELGHYLERN 517 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + + + ++ Q+ A++YLE+ N VH ++ RNIL+A + +KL D Sbjct 518 KNSLKVPTLVLYTLQICKAMAYLESINCVHRDIAVRNILVA-------SPECVKLGD--F 568 Query 763 GLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 GL +E V R+P W++PE + +TA D W F + EI G+ P Sbjct 569 GLSRYIEDEDYYKASVTRLPIKWMSPESI--NFRRFTTASDVWMFAVCMWEILSFGKQPF 626 Query 816 QSRSPSEKEHFYQRQHRLPEPSC--PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + ++ RLP+P P L TL ++C Y+P+ RP F ++ L+ + Sbjct 627 FWLENKDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDI 682 >sp|P42683|LCK_CHICK Proto-oncogene tyrosine-protein kinase LCK OS=Gallus gallus OX=9031 GN=LCK PE=2 SV=2 Length=508 Score = 160 bits (406), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 98/286 (34%), Positives = 147/286 (51%), Gaps = 29/286 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 LK + LG G FG+V + Y+ VA+K LK G S + E ++++ L H Sbjct 244 LKLVEKLGAGQFGEVWMGFYNGHTK-----VAIKNLKQ--GSMSPSAFLAEANLMKNLQH 296 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAY 1013 +++ ++ + ++ EY+ GSL D+L + + +LL A QI EGMA+ Sbjct 297 PRLVRLYAVV---TKEPIYIITEYMEKGSLVDFLKTSEGIKLSINKLLDMAAQIAEGMAF 353 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + A++YIHRDL A N+L+ KI DFGLA+ + + Y RE P+ W APE + Sbjct 354 IEAKNYIHRDLRAANILVSEALCCKIADFGLARLIEDNE--YTAREGAKFPIKWTAPEAI 411 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 F SDVWSFG+ L E++T+ I MT + + LERG R Sbjct 412 NYGTFTIKSDVWSFGILLTEIVTYGR--------------IPYPGMTNPEVIQNLERGYR 457 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+PD CP E+Y LM CW+ + RPTFE + +L+ +GQ Sbjct 458 MPQPDNCPQELYELMMQCWKEQPEERPTFEYMKSVLEDFFTATEGQ 503 Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 69/226 (31%), Positives = 111/226 (49%), Gaps = 25/226 (11%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 AF A+LM + H L ++ V + P I +TEY+E G L +L+ G K++ Sbjct 283 AFLAEANLMKNLQHPRLVRLYAVVTKEPIYI-ITEYMEKGSLVDFLKTSEGIKLSINKLL 341 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----- 767 +A Q+A ++++E KN +H ++ NIL++ + K++D GL L Sbjct 342 DMAAQIAEGMAFIEAKNYIHRDLRAANILVSE-------ALCCKIAD--FGLARLIEDNE 392 Query 768 --SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 +RE I W APE + G ++ + D W FG L EI G P + E Sbjct 393 YTAREGAKFPIKWTAPEAINYGTFTIKS--DVWSFGILLTEIVTYGRIPYPGMTNPEVIQ 450 Query 826 FYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSF---RTILRDL 866 +R +R+P+P +CPQ L L QC +P +RP+F +++L D Sbjct 451 NLERGYRMPQPDNCPQELYELMMQCWKEQPEERPTFEYMKSVLEDF 496 >sp|Q62956|ERBB4_RAT Receptor tyrosine-protein kinase erbB-4 OS=Rattus norvegicus OX=10116 GN=Erbb4 PE=1 SV=3 Length=1308 Score = 166 bits (421), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 107/305 (35%), Positives = 159/305 (52%), Gaps = 21/305 (7%) Query 864 RDLTRLQPHNLADVLTVNPDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922 R L R L + LT + +P + + + LK+++ LG G FG V + P + Sbjct 684 RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGET 743 Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982 VA+K L GP+ + E I+ ++ H H+++ G C ++QLV + +P Sbjct 744 VKIPVAIKILNETTGPKANVEFMDEALIMASVDHPHLVRLLGVCL---SPTIQLVTQLMP 800 Query 983 LGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040 G L +Y+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI Sbjct 801 HGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKIT 860 Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100 DFGLA+ + EG E + G P+ W A EC+ KF + SDVWS+GVT++EL+T Sbjct 861 DFGLARLL-EGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMT---- 915 Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 G + + +LLE+GERLP+P C +VY +M CW +A RP Sbjct 916 ----------FGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYIVMVKCWMIDADSRP 965 Query 1161 TFENL 1165 F+ L Sbjct 966 KFKEL 970 Score = 77.8 bits (190), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 70/302 (23%), Positives = 129/302 (43%), Gaps = 39/302 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 +Q + + E+ ++ LG G VY+G EG E +P Sbjct 706 NQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEG-----------ETVKIP------- 747 Query 637 LRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K+L+ + A + F + A +M+ V H HL + GVC+ P +VT+ + HG L Sbjct 748 --VAIKILNETTGPKANVEFMDEALIMASVDHPHLVRLLGVCL-SPTIQLVTQLMPHGCL 804 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 ++ + ++ + Q+A + YLE + LVH ++ RN+L+ + + Sbjct 805 LEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVK-------SPNHV 857 Query 756 KLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 K++D G+ L +E + I W+A EC+ + D W +G T+ E+ Sbjct 858 KITDFGLARLLEGDEKEYNADGGKMPIKWMALECI--HYRKFTHQSDVWSYGVTIWELMT 915 Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLT 867 G P E ++ RLP+P + + +C + RP F+ + + + Sbjct 916 FGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYIVMVKCWMIDADSRPKFKELAAEFS 975 Query 868 RL 869 R+ Sbjct 976 RM 977 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens OX=9606 GN=PTK2 PE=1 SV=2 Length=1052 Score = 166 bits (419), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 104/282 (37%), Positives = 148/282 (52%), Gaps = 24/282 (9%) Query 901 RDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 R +GEG FG V Y P N VA+K K R + QE +R H HI Sbjct 426 RCIGEGQFGDVHQGIYMSPENPALA--VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 483 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +K G E + ++ME LG LR +L ++S+ LA L+L+A Q+ +AYL ++ Sbjct 484 VKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK 540 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 ++HRD+AARNVL+ ++ VK+GDFGL++ + E YY+ + G P+ W APE + + Sbjct 541 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYM-EDSTYYKASK-GKLPIKWMAPESINFRR 598 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F ASDVW FGV ++E+L H K ++IG +E GERLP P Sbjct 599 FTSASDVWMFGVCMWEILMH-GVKPFQGVKNNDVIG-------------RIENGERLPMP 644 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 CP +Y LM CW + S RP F L L T+ E+ + Q Sbjct 645 PNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQ 686 Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 64/224 (29%), Positives = 107/224 (48%), Gaps = 21/224 (9%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F + A M Q H H+ + GV P I + E G L +L+ + + +A ++ Sbjct 468 FLQEALTMRQFDHPHIVKLIGVITENPVWI-IMELCTLGELRSFLQVRKYSLDLASLILY 526 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 A QL++AL+YLE+K VH ++ RN+L++ ++ +KL D GL + Sbjct 527 AYQLSTALAYLESKRFVHRDIAARNVLVS-------SNDCVKLGD--FGLSRYMEDSTYY 577 Query 775 R-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 + I W+APE + ++A D W FG + EI G P Q ++ Sbjct 578 KASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 635 Query 828 QRQHRLP-EPSC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + RLP P+C P L +L ++C Y+P++RP F + L+ + Sbjct 636 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679 >sp|P41239|CSK_CHICK Tyrosine-protein kinase CSK OS=Gallus gallus OX=9031 GN=CSK PE=2 SV=1 Length=450 Score = 158 bits (400), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 99/282 (35%), Positives = 145/282 (51%), Gaps = 33/282 (12%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 LK ++ +G+G FG V L D G VAVK +K D Q + E ++ L H Sbjct 195 LKLLQIIGKGEFGDVML------GDYRGNKVAVKCIKNDATAQ---AFLAEASVMTQLRH 245 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAY 1013 ++++ G ++ + L +V EY+ GSL DYL R +G LL F+ +CE M Y Sbjct 246 SNLVQLLGVIVEE-KSGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEY 304 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 L A +++HRDLAARNVL+ D + K+ DFGL K E ++ G PV W APE L Sbjct 305 LEANNFVHRDLAARNVLVSEDNIAKVSDFGLTK------EASSTQDTGKLPVKWTAPEAL 358 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +E KF SDVWSFG+ L+E+ + + ++ + + +E+G + Sbjct 359 REKKFSTKSDVWSFGILLWEIYSFGR--------------VPYPRIPLKDVVPRVEKGYK 404 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 + PD CP VY +MK CW + RP+F L L + EK Sbjct 405 MDPPDGCPAIVYEVMKKCWTLDPGHRPSFHQLREQLVHIKEK 446 Score = 84.0 bits (206), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 67/228 (29%), Positives = 107/228 (47%), Gaps = 14/228 (6%) Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLR-RERGHVPMA 709 A AF AS+M+Q+ H++L + GV V + +VTEY+ G L +LR R R + Sbjct 230 AQAFLAEASVMTQLRHSNLVQLLGVIVEEKSGLYIVTEYMAKGSLVDYLRSRGRSVLGGD 289 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 + + + A+ YLE N VH ++ RN+L++ +A K+SD G+ A S Sbjct 290 CLLKFSLDVCEAMEYLEANNFVHRDLAARNVLVSEDNIA-------KVSDFGLTKEASST 342 Query 770 EERVER-IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 ++ + + W APE L ST D W FG L EI G P + + Sbjct 343 QDTGKLPVKWTAPEALR--EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVE 400 Query 829 RQHRLPEPS-CPQLA-TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 + +++ P CP + + +C T +P RPSF + L ++ L Sbjct 401 KGYKMDPPDGCPAIVYEVMKKCWTLDPGHRPSFHQLREQLVHIKEKEL 448 >sp|Q01621|LCK_RAT Proto-oncogene tyrosine-protein kinase LCK OS=Rattus norvegicus OX=10116 GN=Lck PE=1 SV=3 Length=509 Score = 159 bits (403), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 100/289 (35%), Positives = 147/289 (51%), Gaps = 29/289 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 + LK + LG G FG+V + Y+ VAVK+LK G + E ++++ Sbjct 242 RETLKLVERLGAGQFGEVWMGYYNGHTK-----VAVKSLKQ--GSMSPDAFLAEANLMKQ 294 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEG 1010 L H +++ ++ + ++ EY+ GSL D+L S + + +LL A QI EG Sbjct 295 LQHPRLVRLYAVVT---QEPIYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQIAEG 351 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 MA++ Q+YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W AP Sbjct 352 MAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKWTAP 409 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E + F SDVWSFG+ L E++TH I MT + + LE+ Sbjct 410 EAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQNLEK 455 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 G R+ RPD CP E+YHLM CW+ RPTF+ L +L +GQ Sbjct 456 GYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLDDFFTATEGQ 504 Score = 77.8 bits (190), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 66/226 (29%), Positives = 108/226 (48%), Gaps = 25/226 (11%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 AF A+LM Q+ H L ++ V + P I +TEY+E+G L +L+ G K++ Sbjct 284 AFLAEANLMKQLQHPRLVRLYAVVTQEPIYI-ITEYMENGSLVDFLKTPSGIKLNVNKLL 342 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----- 767 +A Q+A ++++E +N +H ++ NIL++ + K++D GL L Sbjct 343 DMAAQIAEGMAFIEEQNYIHRDLRAANILVS-------DTLSCKIAD--FGLARLIEDNE 393 Query 768 --SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 +RE I W APE + G ++ + D W FG L EI G P + E Sbjct 394 YTAREGAKFPIKWTAPEAINYGTFTIKS--DVWSFGILLTEIVTHGRIPYPGMTNPEVIQ 451 Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF---RTILRDL 866 ++ +R+ P +CP +L L C P RP+F R++L D Sbjct 452 NLEKGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLDDF 497 >sp|P34152|FAK1_MOUSE Focal adhesion kinase 1 OS=Mus musculus OX=10090 GN=Ptk2 PE=1 SV=4 Length=1052 Score = 165 bits (417), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 104/282 (37%), Positives = 148/282 (52%), Gaps = 24/282 (9%) Query 901 RDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 R +GEG FG V Y P N VA+K K R + QE +R H HI Sbjct 426 RCIGEGQFGDVHQGVYLSPENPALA--VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 483 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +K G E + ++ME LG LR +L ++S+ LA L+L+A Q+ +AYL ++ Sbjct 484 VKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK 540 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 ++HRD+AARNVL+ ++ VK+GDFGL++ + E YY+ + G P+ W APE + + Sbjct 541 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYM-EDSTYYKASK-GKLPIKWMAPESINFRR 598 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F ASDVW FGV ++E+L H K ++IG +E GERLP P Sbjct 599 FTSASDVWMFGVCMWEILMH-GVKPFQGVKNNDVIG-------------RIENGERLPMP 644 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 CP +Y LM CW + S RP F L L T+ E+ + Q Sbjct 645 PNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQ 686 Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 64/224 (29%), Positives = 107/224 (48%), Gaps = 21/224 (9%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F + A M Q H H+ + GV P I + E G L +L+ + + +A ++ Sbjct 468 FLQEALTMRQFDHPHIVKLIGVITENPVWI-IMELCTLGELRSFLQVRKYSLDLASLILY 526 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 A QL++AL+YLE+K VH ++ RN+L++ ++ +KL D GL + Sbjct 527 AYQLSTALAYLESKRFVHRDIAARNVLVS-------SNDCVKLGD--FGLSRYMEDSTYY 577 Query 775 R-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 + I W+APE + ++A D W FG + EI G P Q ++ Sbjct 578 KASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 635 Query 828 QRQHRLP-EPSC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + RLP P+C P L +L ++C Y+P++RP F + L+ + Sbjct 636 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679 >sp|P06239|LCK_HUMAN Tyrosine-protein kinase Lck OS=Homo sapiens OX=9606 GN=LCK PE=1 SV=6 Length=509 Score = 159 bits (402), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 99/289 (34%), Positives = 149/289 (52%), Gaps = 29/289 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 + LK + LG G FG+V + Y+ VAVK+LK G + E ++++ Sbjct 242 RETLKLVERLGAGQFGEVWMGYYNGHTK-----VAVKSLKQ--GSMSPDAFLAEANLMKQ 294 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEG 1010 L H+ +++ ++ + ++ EY+ GSL D+L S + + +LL A QI EG Sbjct 295 LQHQRLVRLYAVVT---QEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEG 351 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 MA++ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W AP Sbjct 352 MAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKWTAP 409 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E + F SDVWSFG+ L E++TH I MT + + LER Sbjct 410 EAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQNLER 455 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 G R+ RPD CP E+Y LM+ CW+ RPTF+ L +L+ +GQ Sbjct 456 GYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATEGQ 504 Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 67/226 (30%), Positives = 108/226 (48%), Gaps = 25/226 (11%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 AF A+LM Q+ H L ++ V + P I +TEY+E+G L +L+ G K++ Sbjct 284 AFLAEANLMKQLQHQRLVRLYAVVTQEPIYI-ITEYMENGSLVDFLKTPSGIKLTINKLL 342 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----- 767 +A Q+A ++++E +N +H ++ NIL++ + K++D GL L Sbjct 343 DMAAQIAEGMAFIEERNYIHRDLRAANILVS-------DTLSCKIAD--FGLARLIEDNE 393 Query 768 --SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 +RE I W APE + G ++ + D W FG L EI G P + E Sbjct 394 YTAREGAKFPIKWTAPEAINYGTFTIKS--DVWSFGILLTEIVTHGRIPYPGMTNPEVIQ 451 Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF---RTILRDL 866 +R +R+ P +CP +L L C P RP+F R++L D Sbjct 452 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDF 497 >sp|O35346|FAK1_RAT Focal adhesion kinase 1 OS=Rattus norvegicus OX=10116 GN=Ptk2 PE=1 SV=1 Length=1055 Score = 165 bits (417), Expect = 6e-40, Method: Compositional matrix adjust. Identities = 104/282 (37%), Positives = 148/282 (52%), Gaps = 24/282 (9%) Query 901 RDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 R +GEG FG V Y P N VA+K K R + QE +R H HI Sbjct 426 RCIGEGQFGDVHQGVYLSPENPALA--VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 483 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +K G E + ++ME LG LR +L ++S+ LA L+L+A Q+ +AYL ++ Sbjct 484 VKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK 540 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 ++HRD+AARNVL+ ++ VK+GDFGL++ + E YY+ + G P+ W APE + + Sbjct 541 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYM-EDSTYYKASK-GKLPIKWMAPESINFRR 598 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F ASDVW FGV ++E+L H K ++IG +E GERLP P Sbjct 599 FTSASDVWMFGVCMWEILMH-GVKPFQGVKNNDVIG-------------RIENGERLPMP 644 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 CP +Y LM CW + S RP F L L T+ E+ + Q Sbjct 645 PNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQ 686 Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 64/224 (29%), Positives = 107/224 (48%), Gaps = 21/224 (9%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F + A M Q H H+ + GV P I + E G L +L+ + + +A ++ Sbjct 468 FLQEALTMRQFDHPHIVKLIGVITENPVWI-IMELCTLGELRSFLQVRKYSLDLASLILY 526 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 A QL++AL+YLE+K VH ++ RN+L++ ++ +KL D GL + Sbjct 527 AYQLSTALAYLESKRFVHRDIAARNVLVS-------SNDCVKLGD--FGLSRYMEDSTYY 577 Query 775 R-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 + I W+APE + ++A D W FG + EI G P Q ++ Sbjct 578 KASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 635 Query 828 QRQHRLP-EPSC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + RLP P+C P L +L ++C Y+P++RP F + L+ + Sbjct 636 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679 >sp|P42685|FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo sapiens OX=9606 GN=FRK PE=1 SV=1 Length=505 Score = 159 bits (401), Expect = 7e-40, Method: Compositional matrix adjust. Identities = 97/273 (36%), Positives = 145/273 (53%), Gaps = 27/273 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 ++ ++ LG G FG+V ++ T VAVK LK G + + +E I++ L H Sbjct 234 IQLLKRLGSGQFGEVWEGLWNNTTP-----VAVKTLKP--GSMDPNDFLREAQIMKNLRH 286 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAY 1013 +I+ C E + ++ E + GSL++YL + I L Q + A Q+ GMAY Sbjct 287 PKLIQLYAVC--TLEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAY 344 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPEC 1072 L +++YIHRDLAARNVL+ + K+ DFGLA+ + + Y R + PV W APE Sbjct 345 LESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEA 404 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 ++ KF SDVWSFG+ LYE++T+ S MT ++ ++L + Sbjct 405 IRSNKFSIKSDVWSFGILLYEIITYGKMPYSG--------------MTGAQVIQMLAQNY 450 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 RLP+P CP + Y++M CW E RPTFE L Sbjct 451 RLPQPSNCPQQFYNIMLECWNAEPKERPTFETL 483 Score = 104 bits (259), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 81/296 (27%), Positives = 133/296 (45%), Gaps = 43/296 (15%) Query 579 LSFHRVDQKEITQ-----LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 LS+ VDQ EI + L LG G V+EG ++ P Sbjct 219 LSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGL-------------WNNTTP------- 258 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 V +K L P D F A +M + H L ++ VC ++TE + HG Sbjct 259 -----VAVKTLKPGSMDPN-DFLREAQIMKNLRHPKLIQLYAVCTLEDPIYIITELMRHG 312 Query 694 PLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE--- 749 L +L+ + G + + ++ +A Q+AS ++YLE++N +H ++ RN+L+ + + Sbjct 313 SLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVAD 372 Query 750 -GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 G + K+ + + SR E + W APE + +N S D W FG L EI Sbjct 373 FGLARVFKVDNEDI---YESRHEIKLPVKWTAPEAIR--SNKFSIKSDVWSFGILLYEII 427 Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862 G+ P + ++ + +RLP+PS CP Q + +C EP +RP+F T+ Sbjct 428 TYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERPTFETL 483 >sp|Q922K9|FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus musculus OX=10090 GN=Frk PE=1 SV=3 Length=512 Score = 159 bits (402), Expect = 7e-40, Method: Compositional matrix adjust. Identities = 98/284 (35%), Positives = 147/284 (52%), Gaps = 27/284 (10%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 +D + ++ ++ LG G FG+V ++ T VAVK LK G + + Sbjct 230 TADQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTP-----VAVKTLKP--GSMDPNDFL 282 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLL 1002 +E I+++L H +I+ C E + ++ E + GSL++YL I L Q + Sbjct 283 REAQIMKSLRHPKLIQLYAVC--TLEDPIYIITELMRHGSLQEYLQNDGGSKIHLIQQVD 340 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDG 1061 A Q+ GMAYL +Q+YIHRDLAARNVL+ + K+ DFGLA+ + + Y + + Sbjct 341 MAAQVASGMAYLESQNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESKHEI 400 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 PV W APE ++ KF SDVWSFG+ LYE++T+ S MT Sbjct 401 KLPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGKMPYSG--------------MTG 446 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 ++ ++L + RLP+P CP + Y +M CW E RPTFE L Sbjct 447 AQVIQMLSQNYRLPQPSNCPQQFYSIMLECWNVEPKQRPTFETL 490 Score = 102 bits (255), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 80/304 (26%), Positives = 133/304 (44%), Gaps = 46/304 (15%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P L+ +D+ I L LG G V+EG ++ P Sbjct 222 TPFDLSYKTADQWEIDRNSIQLLKRLGSGQFGEVWEGL-------------WNNTTP--- 265 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 V +K L P D F A +M + H L ++ VC ++TE Sbjct 266 ---------VAVKTLKPGSMDPN-DFLREAQIMKSLRHPKLIQLYAVCTLEDPIYIITEL 315 Query 690 VEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + HG L +L+ + G + + ++ +A Q+AS ++YLE++N +H ++ RN+L+ Sbjct 316 MRHGSLQEYLQNDGGSKIHLIQQVDMAAQVASGMAYLESQNYIHRDLAARNVLV------ 369 Query 749 EGTSPFIKLSDPGVG-LGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGF 800 G K++D G+ + + E+ E + W APE + N S D W F Sbjct 370 -GEHNIYKVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIR--TNKFSIKSDVWSF 426 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPS 858 G L EI G+ P + ++ + +RLP+PS CP Q ++ +C EP QRP+ Sbjct 427 GILLYEIITYGKMPYSGMTGAQVIQMLSQNYRLPQPSNCPQQFYSIMLECWNVEPKQRPT 486 Query 859 FRTI 862 F T+ Sbjct 487 FETL 490 >sp|P42690|SRK4_SPOLA Tyrosine-protein kinase isoform SRK4 OS=Spongilla lacustris OX=6055 GN=SRK1 PE=2 SV=1 Length=506 Score = 159 bits (401), Expect = 7e-40, Method: Compositional matrix adjust. Identities = 111/333 (33%), Positives = 168/333 (50%), Gaps = 44/333 (13%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP---------------ASDPTVFHK 894 TY T+R +F++I ++L AD L VN P A++ K Sbjct 180 TYFVTRRLTFQSI-QELVAYYTQQ-ADGLCVNLKGPCMVMEKPQTAGLSKQANEEWEIEK 237 Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 + +K +R LG G FG+V ++ T VAVK LK G + +E I++ L Sbjct 238 KQIKLLRGLGAGQFGEVWEGLWNGTTS-----VAVKTLKP--GTMSIEEFLEEASIMKQL 290 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMA 1012 H +I+ C E+ + +V E + GSL +YL S+ L L+ Q+ GM+ Sbjct 291 RHPKLIQLYAVCTK--EEPIYIVTELMKHGSLLEYLRGDGRSLKLPDLVDMCSQVASGMS 348 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 YL Q+YIHRDLAARN+L+ ++ K+ DFGLA+ + E E Y + P+ W APE Sbjct 349 YLEQQNYIHRDLAARNILVGEHKICKVADFGLARVIDE--EIYEAKLGAKFPIKWTAPEA 406 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 +F SDVWSFG+ LYE++T+ + P MT ++ E +++ Sbjct 407 AMYSRFTIKSDVWSFGIVLYEVITY---GRFPYPG-----------MTNAQVLEQIQQSY 452 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 R+PRP CP ++Y +M +CW + + RPTFE L Sbjct 453 RMPRPMGCPEKLYAIMMDCWREDPASRPTFETL 485 Score = 100 bits (248), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 103/405 (25%), Positives = 165/405 (41%), Gaps = 74/405 (18%) Query 469 GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRE 528 G +LI S + P L+V R+R + I++ + +F S++E Sbjct 144 GSFLIRDSDTTPGDFSLSVRDID---------RVRHYRIKKLENGTYFVTRRLTFQSIQE 194 Query 529 LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHR--VDQ 586 L A +A C +L+ C+ P+T LS+ + +++ Sbjct 195 LVAYYTQ---QADGLCVNLKGPCM--------------VMEKPQTAGLSKQANEEWEIEK 237 Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 K+I L LG G V+EG S V +K L P Sbjct 238 KQIKLLRGLGAGQFGEVWEGLWNGTTS-------------------------VAVKTLKP 272 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 I F E AS+M Q+ H L ++ VC + +VTE ++HG L +LR + + Sbjct 273 GTMSIE-EFLEEASIMKQLRHPKLIQLYAVCTKEEPIYIVTELMKHGSLLEYLRGDGRSL 331 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + + + Q+AS +SYLE +N +H ++ RNIL+ G K++D GL Sbjct 332 KLPDLVDMCSQVASGMSYLEQQNYIHRDLAARNILV-------GEHKICKVAD--FGLAR 382 Query 767 LSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + EE E I W APE + + D W FG L E+ G P + Sbjct 383 VIDEEIYEAKLGAKFPIKWTAPEA--AMYSRFTIKSDVWSFGIVLYEVITYGRFPYPGMT 440 Query 820 PSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 ++ Q+ +R+P P CP+ L + C +P RP+F T+ Sbjct 441 NAQVLEQIQQSYRMPRPMGCPEKLYAIMMDCWREDPASRPTFETL 485 >sp|P08631|HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo sapiens OX=9606 GN=HCK PE=1 SV=5 Length=526 Score = 159 bits (401), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 94/286 (33%), Positives = 145/286 (51%), Gaps = 29/286 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 LK + LG G FG+V + Y+ VAVK +K G + E ++++TL H Sbjct 262 LKLEKKLGAGQFGEVWMATYNKHTK-----VAVKTMKP--GSMSVEAFLAEANVMKTLQH 314 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAY 1013 + ++K + + ++ E++ GSL D+L L +L+ F+ QI EGMA+ Sbjct 315 DKLVKLHAVVTKE---PIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAF 371 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W APE + Sbjct 372 IEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAI 429 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 F SDVWSFG+ L E++T+ I M+ + LERG R Sbjct 430 NFGSFTIKSDVWSFGILLMEIVTYGR--------------IPYPGMSNPEVIRALERGYR 475 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +PRP+ CP E+Y++M CW+ RPTFE + +L + + Q Sbjct 476 MPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ 521 Score = 88.2 bits (217), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 65/234 (28%), Positives = 110/234 (47%), Gaps = 21/234 (9%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K + P + AF A++M + H L +H V + P I +TE++ G L Sbjct 286 KVAVKTMKPGSMSVE-AFLAEANVMKTLQHDKLVKLHAVVTKEPIYI-ITEFMAKGSLLD 343 Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ + G P+ + + Q+A ++++E +N +H ++ NIL++ S K Sbjct 344 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-------ASLVCK 396 Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 ++D G+ + E R I W APE + G S + D W FG L+EI Sbjct 397 IADFGLAR-VIEDNEYTAREGAKFPIKWTAPEAINFG--SFTIKSDVWSFGILLMEIVTY 453 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTI 862 G P S E +R +R+P P +CP +L + +C P +RP+F I Sbjct 454 GRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYI 507 >sp|Q24592|JAK_DROME Tyrosine-protein kinase hopscotch OS=Drosophila melanogaster OX=7227 GN=hop PE=1 SV=2 Length=1177 Score = 164 bits (415), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 161/574 (28%), Positives = 252/574 (44%), Gaps = 69/574 (12%) Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 +++ V +K+L + + F+ A S + ++G+ + P MV EY +GP Sbjct 608 KDVSVTMKMLKSDGN--FMEFFRLAQTWSLIQSPQFLKLYGLTLADPYT-MVMEYSRYGP 664 Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 L+ +L +V + + + L + YLE+ ++H + N+ + + Sbjct 665 LNKFLH-SMPNVTLHCLLDLMHGLVRGMHYLEDNKIIHNYIRCSNLYVTKYD-PNSYVLD 722 Query 755 IKLSDPGVGLGALSREERVERIPWLAPECLPG-GANSLSTAMDKWGFGATLLEI---CFD 810 K+SDPG R R PW+ + A W F T+ EI C + Sbjct 723 AKISDPGY-----PRPYRESDSPWIPVKYYRNLQAAKTDQFAQLWAFATTIYEIFSRCKE 777 Query 811 GEAPL-QSRSPSEKEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTR 868 + L Q + +K L + CP + + + T+R S I L Sbjct 778 DLSTLRQEQLLRQKNLDGNILKMLDQDICPAPIFETIMDGWSDDETKRFSHHDIFSRLNT 837 Query 869 LQPHNLADVL-------------TVNPDS-------PASD-----PTVFHKRYLKKIRDL 903 ++ L + + TV S P S+ P R + + ++ Sbjct 838 IKAEILPNYMPPPEIATNGTGDETVIDRSDIPFLPFPRSNMLMVIPLTSECRVIYNMENM 897 Query 904 -GEGHFGKVSLYCYDPTN-DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 G GH+G V + + D E VA+K L Q + + +EI I+RTL H +I+K Sbjct 898 IGRGHYGTVYKGHLEFNDKDQPREQVAIKMLNT---MQVSTDFHREIGIMRTLSHPNIVK 954 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019 +K EKS ++MEY+ GS YL + L +L+ FA I GM YL Sbjct 955 FKYW----AEKSHCIIMEYLQSGSFDIYLRFTAPNLNNPRLVSFALDIANGMKYLSDMGL 1010 Query 1020 IHRDLAARNVLLDND---RLVKIGDFGLAK-AVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 IHRDLAARN+L+D++ VKI DFGLA+ A +G YY + D P+ WY+PE + Sbjct 1011 IHRDLAARNILVDHNGDGDCVKISDFGLAQFANSDG--YYYAKSKRDIPIRWYSPEAIST 1068 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 +F SDVWS+GVTL+E+ + + L+ I Q L L+ GERL Sbjct 1069 CRFSSYSDVWSYGVTLFEMFSRGEEPN--------LVPIQTSQEDFL---NRLQSGERLN 1117 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 RP CP +Y LM+ CW RP+F ++ I+ Sbjct 1118 RPASCPDFIYDLMQLCWHATPRSRPSFATIVDII 1151 Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 73/285 (26%), Positives = 121/285 (42%), Gaps = 40/285 (14%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 +G+G VY+G L P E +V +K+L+ ++ Sbjct 898 IGRGHYGTVYKGHLEFNDKDQPRE-------------------QVAIKMLNTMQ--VSTD 936 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F+ +M +SH ++ + + ++ EY++ G D++LR ++ + Sbjct 937 FHREIGIMRTLSHPNIVKFKYWAEKS--HCIIMEYLQSGSFDIYLRFTAPNLNNPRLVSF 994 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS------ 768 A +A+ + YL + L+H ++ RNIL+ G +K+SD G+ A S Sbjct 995 ALDIANGMKYLSDMGLIHRDLAARNILVDH----NGDGDCVKISDFGLAQFANSDGYYYA 1050 Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 + +R I W +PE + S+ D W +G TL E+ GE P + +E F Sbjct 1051 KSKRDIPIRWYSPEAI--STCRFSSYSDVWSYGVTLFEMFSRGEEPNLVPIQTSQEDFLN 1108 Query 829 RQH---RLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTR 868 R RL P SCP + L C P RPSF TI+ +TR Sbjct 1109 RLQSGERLNRPASCPDFIYDLMQLCWHATPRSRPSFATIVDIITR 1153 Score = 45.8 bits (107), Expect = 0.003, Method: Compositional matrix adjust. Identities = 51/206 (25%), Positives = 84/206 (41%), Gaps = 31/206 (15%) Query 976 LVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL- 1031 +VMEY G L +L HS + L LL + GM YL IH + N+ + Sbjct 655 MVMEYSRYGPLNKFL--HSMPNVTLHCLLDLMHGLVRGMHYLEDNKIIHNYIRCSNLYVT 712 Query 1032 --DNDRLV---KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 D + V KI D G + YR + PV +Y L+ K + +W+ Sbjct 713 KYDPNSYVLDAKISDPGYPRP-------YRESDSPWIPVKYY--RNLQAAKTDQFAQLWA 763 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 F T+YE+ + C +L + Q Q+ LR L ++ D CP ++ Sbjct 764 FATTIYEIFSRCKE---------DLSTLRQEQL--LRQKNLDGNILKMLDQDICPAPIFE 812 Query 1147 LMKNCWETEASFRPTFENLIPILKTV 1172 + + W + + R + ++ L T+ Sbjct 813 TIMDGWSDDETKRFSHHDIFSRLNTI 838 >sp|Q03142|FGFR4_MOUSE Fibroblast growth factor receptor 4 OS=Mus musculus OX=10090 GN=Fgfr4 PE=1 SV=3 Length=799 Score = 162 bits (410), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 112/322 (35%), Positives = 160/322 (50%), Gaps = 42/322 (13%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADC 936 VN D P F + L + LGEG FG+V + DP+ VAVK LK + Sbjct 447 VNLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPSRPDQTSTVAVKMLKDNA 506 Query 937 GPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----- 990 + + E+++++ + H++II G C +G L +++E G+LR++L Sbjct 507 SDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEG--PLYVIVECAAKGNLREFLRARRP 564 Query 991 ---------PRHSIG---LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 PR S G L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++K Sbjct 565 PGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDDVMK 624 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 I DFGLA+ V +YY+ +G PV W APE L + + + SDVWSF + L+E+ T Sbjct 625 IADFGLARGV-HHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFEILLWEIFT-- 681 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 L G + V L LL G R+ RP CP E+Y LM+ CW S Sbjct 682 ------------LGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRECWHAAPSQ 729 Query 1159 RPTFENLI----PILKTVHEKY 1176 RPTF+ L+ +L V E+Y Sbjct 730 RPTFKQLVEALDKVLLAVSEEY 751 Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 70/282 (25%), Positives = 120/282 (43%), Gaps = 38/282 (13%) Query 635 QELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 Q V +K+L + S D+A E + H ++ + GVC + ++ E Sbjct 493 QTSTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAK 552 Query 693 GPLDVWLRRER-------------GHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCG 737 G L +LR R P+++ +V A Q+A + YLE++ +H ++ Sbjct 553 GNLREFLRARRPPGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDLAA 612 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSL 791 RN+L+ +K++D G+ G ++ R+P W+APE L + Sbjct 613 RNVLVTE-------DDVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTH 665 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCL 849 + D W F L EI G +P E + HR+ P+CP +L L +C Sbjct 666 QS--DVWSFEILLWEIFTLGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRECW 723 Query 850 TYEPTQRPSFRTILRDLTR----LQPHNLADVLTVNPDSPAS 887 P+QRP+F+ ++ L + + L LT P SP++ Sbjct 724 HAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPFSPSN 765 >sp|P22455|FGFR4_HUMAN Fibroblast growth factor receptor 4 OS=Homo sapiens OX=9606 GN=FGFR4 PE=1 SV=2 Length=802 Score = 162 bits (410), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 109/310 (35%), Positives = 156/310 (50%), Gaps = 42/310 (14%) Query 892 FHKRYLKKIRDLGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 F + L + LGEG FG+V + DP VAVK LK + + + E+ Sbjct 462 FPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEM 521 Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--------------PRH 993 ++++ + H++II G C +G L +++E G+LR++L PR Sbjct 522 EVMKLIGRHKNIINLLGVCTQEG--PLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRS 579 Query 994 SIG---LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 S G L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ V Sbjct 580 SEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGV-H 638 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 +YY+ +G PV W APE L + + + SDVWSFG+ L+E+ T Sbjct 639 HIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFT-------------- 684 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI---- 1166 L G + V L LL G R+ RP CP E+Y LM+ CW S RPTF+ L+ Sbjct 685 LGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALD 744 Query 1167 PILKTVHEKY 1176 +L V E+Y Sbjct 745 KVLLAVSEEY 754 Score = 67.4 bits (163), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 72/289 (25%), Positives = 122/289 (42%), Gaps = 38/289 (13%) Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 DP P D+ + V + + S D+A E + H ++ + GVC + Sbjct 490 DPARP--DQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLY 547 Query 685 MVTEYVEHGPLDVWLRRER-------------GHVPMAWKMVV--AQQLASALSYLENKN 729 ++ E G L +LR R P+++ ++V A Q+A + YLE++ Sbjct 548 VIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRK 607 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPEC 783 +H ++ RN+L+ + +K++D G+ G ++ R+P W+APE Sbjct 608 CIHRDLAARNVLVTEDNV-------MKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA 660 Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-C-PQL 841 L + D W FG L EI G +P E + HR+ P C P+L Sbjct 661 L--FDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPEL 718 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTR----LQPHNLADVLTVNPDSPA 886 L +C P+QRP+F+ ++ L + + L LT P SP+ Sbjct 719 YGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPS 767 >sp|Q07407|FGFR1_DROME Fibroblast growth factor receptor homolog 1 OS=Drosophila melanogaster OX=7227 GN=htl PE=1 SV=3 Length=729 Score = 161 bits (408), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 98/289 (34%), Positives = 149/289 (52%), Gaps = 44/289 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961 LGEG FG+V + + +VAVK +K + +E+++++ + H +II Sbjct 422 LGEGAFGRVVMA------EVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIIN 475 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------------------HSIGLAQL 1000 GCC G L +++EY P G+L+D+L + H I L Sbjct 476 LLGCCSQNG--PLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDL 533 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 + FA QI GM YL ++ IHRDLAARNVL+ +D ++KI DFGLA+ + + +YYR + Sbjct 534 IKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDI-QSTDYYRKNTN 592 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 G P+ W APE L+E + SDVWS+G+ L+E++T+ Q PT M+ Sbjct 593 GRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTY--GQQPYPTI-----------MS 639 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 L L G+R+ +P KC +Y LM+ CW A RP F ++ + Sbjct 640 AEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYM 688 Score = 64.7 bits (156), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 67/282 (24%), Positives = 113/282 (40%), Gaps = 43/282 (15%) Query 639 VVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K++ H DIA E + H ++ + G C + ++ EY HG L Sbjct 440 VAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNGPLYVIVEYAPHGNLK 499 Query 697 VWLRRER------------------GHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCG 737 +L + R HV ++ A Q+A + YL ++ +H ++ Sbjct 500 DFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAA 559 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGANSL 791 RN+L++ +K++D G+ S R+ R+P W+APE L Sbjct 560 RNVLVS-------DDYVLKIADFGLARDIQSTDYYRKNTNGRLPIKWMAPESLQ--EKFY 610 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY----QRQHRLPEPSCPQLATLTSQ 847 + D W +G L EI G+ P + +E+ + Y QR + P + L Q Sbjct 611 DSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELYTYLMSGQRMEK-PAKCSMNIYILMRQ 669 Query 848 CLTYEPTQRPSFRTILRDLTRL--QPHNLADVLTVNPDSPAS 887 C + RP F I+ + +L + DV N D+P S Sbjct 670 CWHFNADDRPPFTEIVEYMDKLLQTKEDYLDVDIANLDTPPS 711 >sp|Q62662|FRK_RAT Tyrosine-protein kinase FRK OS=Rattus norvegicus OX=10116 GN=Frk PE=1 SV=3 Length=506 Score = 157 bits (397), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 97/273 (36%), Positives = 143/273 (52%), Gaps = 27/273 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 ++ ++ LG G FG+V ++ T VAVK LK G + + +E I+++L H Sbjct 235 IQLLKRLGSGQFGEVWEGLWNNTTP-----VAVKTLKP--GSMDPNDFLREAQIMKSLRH 287 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAY 1013 +I+ C E + ++ E + GSL++YL I L Q + A Q+ GMAY Sbjct 288 PKLIQLYAVC--TLEDPIYIITELMRHGSLQEYLQNDGGSKIRLTQQVDMAAQVASGMAY 345 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPEC 1072 L +Q+YIHRDLAARNVL+ + K+ DFGLA+ + + Y + + PV W APE Sbjct 346 LESQNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEA 405 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 ++ KF SDVWSFG+ LYE++T+ S MT ++ +L + Sbjct 406 IRTNKFSIKSDVWSFGILLYEIITYGKMPYSG--------------MTGAQVIHMLGQNY 451 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 RLP+P CP + Y +M CW E RPTFE L Sbjct 452 RLPQPSNCPEQFYSIMMECWNVEPKQRPTFETL 484 Score = 107 bits (268), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 91/330 (28%), Positives = 142/330 (43%), Gaps = 61/330 (18%) Query 579 LSFHRVDQKEITQ-----LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 LS+ VDQ EI + L LG G V+EG ++ P Sbjct 220 LSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGL-------------WNNTTP------- 259 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 V +K L P D F A +M + H L ++ VC ++TE + HG Sbjct 260 -----VAVKTLKPGSMDPN-DFLREAQIMKSLRHPKLIQLYAVCTLEDPIYIITELMRHG 313 Query 694 PLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752 L +L+ + G + + ++ +A Q+AS ++YLE++N +H ++ RN+L+ G Sbjct 314 SLQEYLQNDGGSKIRLTQQVDMAAQVASGMAYLESQNYIHRDLAARNVLV-------GEH 366 Query 753 PFIKLSDPGVG-LGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATL 804 K++D G+ + + E+ E + W APE + N S D W FG L Sbjct 367 NIYKVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIR--TNKFSIKSDVWSFGILL 424 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862 EI G+ P + ++ H + +RLP+PS CP Q ++ +C EP QRP+F T+ Sbjct 425 YEIITYGKMPYSGMTGAQVIHMLGQNYRLPQPSNCPEQFYSIMMECWNVEPKQRPTFETL 484 Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVF 892 L PDS SD F Sbjct 485 HWKLEDY----------FEPDSSYSDTNNF 504 >sp|Q24145|SHARK_DROME Tyrosine-protein kinase Shark OS=Drosophila melanogaster OX=7227 GN=Shark PE=1 SV=2 Length=939 Score = 162 bits (411), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 102/293 (35%), Positives = 158/293 (54%), Gaps = 40/293 (14%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM----VAVKALKADCGPQHRSGWKQEIDILRTLYH 956 R++G G FG V + G GE VA+K L + ++ + +E ++ L H Sbjct 666 REIGHGEFGSVH-SGWLLRKSGAGEESRLEVAIKMLSDEHS--NKQEFLREASVMMRLEH 722 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAY 1013 + I++ G +GE L +V E PLGS+ Y+ H A+L ++A QI GM Y Sbjct 723 KCIVRLIGIA--KGEM-LMMVQELAPLGSMLQYILDHGHEITANAELKVWASQIACGMHY 779 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 L +QH++HRDLAARN+LL KI DFG+++++ G Y+ + G P+ WYAPE Sbjct 780 LESQHFVHRDLAARNILLTARHQAKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESF 839 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 F +ASDVWSFGVT++E+ S +PP G+++ + +L++ GER Sbjct 840 NLGIFSHASDVWSFGVTIWEMF----SLGAPP----------YGEISNVDAIKLVDSGER 885 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTF-------------ENLIPILKTVH 1173 LP+P+ CP +Y +M++CW+ RPTF +NL +++TVH Sbjct 886 LPQPNLCPAYIYAVMQSCWKERPKDRPTFVYLTEFFARDPDYQNLPELVQTVH 938 Score = 68.2 bits (165), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 70/241 (29%), Positives = 104/241 (43%), Gaps = 23/241 (10%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G L V +K+L H + F AS+M ++ H + + G+ +G +MV E Sbjct 686 GAGEESRLEVAIKMLSDEHSN-KQEFLREASVMMRLEHKCIVRLIGIA-KGEMLMMVQEL 743 Query 690 VEHGPLDVWLRRERGH--VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 G + ++ + GH A V A Q+A + YLE+++ VH ++ RNILL Sbjct 744 APLGSMLQYIL-DHGHEITANAELKVWASQIACGMHYLESQHFVHRDLAARNILLTARHQ 802 Query 748 AEGTSPFIKLSDPGV--GLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGF 800 A K+SD G+ L S E + + I W APE G S A D W F Sbjct 803 A-------KISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESFNLGI--FSHASDVWSF 853 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPS 858 G T+ E+ G P S + RLP+P+ CP + + C P RP+ Sbjct 854 GVTIWEMFSLGAPPYGEISNVDAIKLVDSGERLPQPNLCPAYIYAVMQSCWKERPKDRPT 913 Query 859 F 859 F Sbjct 914 F 914 >sp|Q498D6|FGFR4_RAT Fibroblast growth factor receptor 4 OS=Rattus norvegicus OX=10116 GN=Fgfr4 PE=1 SV=1 Length=800 Score = 161 bits (408), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 107/301 (36%), Positives = 153/301 (51%), Gaps = 42/301 (14%) Query 901 RDLGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956 + LGEG FG+V D + VAVK LK + + + E+++++ + H Sbjct 469 KPLGEGCFGQVVRAEALGMDSSRPDQTSTVAVKMLKDNASDKDLADLISEMEMMKLIGRH 528 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--------------PRHSIG---LAQ 999 ++II G C +G L +++EY G+LR++L PR S G Sbjct 529 KNIINLLGVCTQEG--PLYVIVEYAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPA 586 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ V +YY+ Sbjct 587 LVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDDVMKIADFGLARGV-HHIDYYKKTS 645 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 +G PV W APE L + + + SDVWSFG+ L+E+ T L G + Sbjct 646 NGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFT--------------LGGSPYPGI 691 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI----PILKTVHEK 1175 V L LL G R+ RP CP E+Y LM+ CW S RPTF+ L+ +L V E+ Sbjct 692 PVEELFSLLREGHRMERPPNCPSELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEE 751 Query 1176 Y 1176 Y Sbjct 752 Y 752 Score = 70.5 bits (171), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 66/260 (25%), Positives = 114/260 (44%), Gaps = 34/260 (13%) Query 635 QELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 Q V +K+L + S D+A E + H ++ + GVC + ++ EY Sbjct 494 QTSTVAVKMLKDNASDKDLADLISEMEMMKLIGRHKNIINLLGVCTQEGPLYVIVEYAAK 553 Query 693 GPLDVWLRRER-------------GHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCG 737 G L +LR R P+++ +V A Q+A + YLE++ +H ++ Sbjct 554 GNLREFLRARRPPGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDLAA 613 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSL 791 RN+L+ +K++D G+ G ++ R+P W+APE L + Sbjct 614 RNVLVTE-------DDVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTH 666 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCL 849 + D W FG L EI G +P E + HR+ P+CP +L L +C Sbjct 667 QS--DVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRECW 724 Query 850 TYEPTQRPSFRTILRDLTRL 869 P+QRP+F+ ++ L ++ Sbjct 725 HAAPSQRPTFKQLVEALDKV 744 >sp|P00522|ABL_DROME Tyrosine-protein kinase Abl OS=Drosophila melanogaster OX=7227 GN=Abl PE=1 SV=3 Length=1620 Score = 163 bits (413), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 101/290 (35%), Positives = 154/290 (53%), Gaps = 27/290 (9%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 TV P SP D + + LG G +G+V Y+ G VAVK LK D Sbjct 353 TVFPLSPEPDEWEICRTDIMMKHKLGGGQYGEV----YEAVWKRYGNTVAVKTLKEDT-- 406 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSI 995 + +E I++ + H ++++ G C E ++ E++ G+L D+L R ++ Sbjct 407 MALKDFLEEAAIMKEMKHPNLVQLIGVCTR--EPPFYIITEFMSHGNLLDFLRSAGRETL 464 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 LL A QI GM+YL +++YIHRDLAARN L+ +++LVK+ DFGLA+ + + + Y Sbjct 465 DAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMRD--DTY 522 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 P+ W APE L KF SDVW+FGV L+E+ T+ S P ++L + Sbjct 523 TAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMS----PYPAIDLTDVY 578 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L++G R+ RP CP EVY LM+ CW+ +A+ RPTF+++ Sbjct 579 HK----------LDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSI 618 Score = 104 bits (260), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 70/218 (32%), Positives = 112/218 (51%), Gaps = 21/218 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMV 713 F E A++M ++ H +L + GVC R P ++TE++ HG L +LR R + + Sbjct 412 FLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLY 471 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 +A Q+AS +SYLE++N +H ++ RN L+ G + +K++D GL L R++ Sbjct 472 MATQIASGMSYLESRNYIHRDLAARNCLV-------GDNKLVKVAD--FGLARLMRDDTY 522 Query 774 ER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 I W APE L N ST D W FG L EI G +P + ++ H Sbjct 523 TAHAGAKFPIKWTAPEGL--AYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHK 580 Query 827 YQRQHRLPE-PSC-PQLATLTSQCLTYEPTQRPSFRTI 862 + +R+ P C P++ L QC ++ T RP+F++I Sbjct 581 LDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSI 618 >sp|Q91287|FGFR3_PLEWA Fibroblast growth factor receptor 3 OS=Pleurodeles waltl OX=8319 GN=FGFR3 PE=2 SV=1 Length=796 Score = 161 bits (407), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 106/295 (36%), Positives = 150/295 (51%), Gaps = 42/295 (14%) Query 901 RDLGEGHFGKVSL-----YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL- 954 + LGEG FG+V + D N T VAVK LK D + S E+++++ + Sbjct 461 KPLGEGCFGQVVMADAVGIEKDKPNKATS--VAVKMLKDDATDKDLSDLVSEMEMMKMIG 518 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGL 997 H++II G C G L +++EY G+LR+YL P + Sbjct 519 KHKNIINLLGACTQDG--PLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKLPEEQLTF 576 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 L+ A Q+ GM YL +Q IHRDLAARNVL+ +D ++KI DFGLA+ V +YY+ Sbjct 577 KDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDV-HNIDYYKK 635 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 +G PV W APE L + + + SDVWSFGV L+E+ T L G Sbjct 636 TTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFT--------------LGGSPYP 681 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + V L +LL+ G R+ +P C E+Y +M+ CW S RPTF+ L+ L V Sbjct 682 GIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFKQLVEDLDRV 736 Score = 63.5 bits (153), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 72/284 (25%), Positives = 126/284 (44%), Gaps = 44/284 (15%) Query 639 VVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPL 695 V +K+L D + D++ E + H ++ + G C + GP ++V EY G L Sbjct 490 VAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLV-EYASKGNL 548 Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740 +LR R +P + +K +V A Q+A + YL ++ +H ++ RN+ Sbjct 549 REYLRARRPPGMDYSFDTCKLPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNV 608 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGANSLSTA 794 L+ + +K++D G+ + ++ R+P W+APE L + + Sbjct 609 LVTDDNV-------MKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQS- 660 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYE 852 D W FG L EI G +P E + HR+ +P+ C +L + +C Sbjct 661 -DVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAV 719 Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896 P+QRP+F+ ++ DL R VLTV D +V ++Y Sbjct 720 PSQRPTFKQLVEDLDR--------VLTVTSTDEYLDLSVPFEQY 755 >sp|Q04589|FGFR1_RAT Fibroblast growth factor receptor 1 OS=Rattus norvegicus OX=10116 GN=Fgfr1 PE=1 SV=1 Length=822 Score = 161 bits (407), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 102/293 (35%), Positives = 149/293 (51%), Gaps = 38/293 (13%) Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956 + LGEG FG+V L D VAVK LK+D + S E+++++ + H Sbjct 482 KPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKH 541 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999 ++II G C G L +++EY G+LR+YL P + Sbjct 542 KNIINLLGACTQDG--PLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKD 599 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+ Sbjct 600 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDI-HHIDYYKKTT 658 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 +G PV W APE L + + + SDVWSFGV L+E+ T L G + Sbjct 659 NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--------------LGGSPNPGV 704 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L + Sbjct 705 PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWNAVPSQRPTFKQLVEDLDRI 757 Score = 67.0 bits (162), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 63/257 (25%), Positives = 112/257 (44%), Gaps = 34/257 (13%) Query 638 RVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 +V +K+L D + D++ E + H ++ + G C + ++ EY G L Sbjct 510 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL 569 Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740 +L+ R H P ++ K +V A Q+A + YL +K +H ++ RN+ Sbjct 570 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV 629 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTA 794 L+ + +K++D G+ ++ R+P W+APE L + + Sbjct 630 LVTEDNV-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQS- 681 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATLTSQCLTYE 852 D W FG L EI G +P E + HR+ +PS +L + C Sbjct 682 -DVWSFGVLLWEIFTLGGSPNPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWNAV 740 Query 853 PTQRPSFRTILRDLTRL 869 P+QRP+F+ ++ DL R+ Sbjct 741 PSQRPTFKQLVEDLDRI 757 >sp|P48025|KSYK_MOUSE Tyrosine-protein kinase SYK OS=Mus musculus OX=10090 GN=Syk PE=1 SV=2 Length=629 Score = 159 bits (401), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 103/289 (36%), Positives = 144/289 (50%), Gaps = 27/289 (9%) Query 883 DSPASDPT------VFHKRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 +SP +DP V+ R L + D LG G+FG V Y V + +A Sbjct 343 ESPYADPEEIRPKEVYLDRSLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEA 402 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994 + P + E ++++ L + +I++ G CE + S LVME LG L YL ++ Sbjct 403 N-DPALKDELLAEANVMQQLDNPYIVRMIGICEAE---SWMLVMEMAELGPLNKYLQQNR 458 Query 995 -IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 I ++ Q+ GM YL +++HRDLAARNVLL KI DFGL+KA+ Sbjct 459 HIKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN 518 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 YY+ + G PV WYAPEC+ YKF SDVWSFGV ++E ++ Q P Sbjct 519 YYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSY---GQKPYRG------ 569 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 M +T +LE+GER+ P CP E+Y LM CW + RP F Sbjct 570 -----MKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGF 613 Score = 87.0 bits (214), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 64/228 (28%), Positives = 108/228 (47%), Gaps = 25/228 (11%) Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 DP+ D LA A++M Q+ + ++ + G+C ++V E E GPL+ +L++ R Sbjct 404 DPALKDELLA---EANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNR- 458 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 H+ + + Q++ + YLE N VH ++ RN+LL T + K+SD G+ Sbjct 459 HIKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLV-------TQHYAKISDFGLS- 510 Query 765 GALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 AL +E + + W APEC+ S+ D W FG + E G+ P + Sbjct 511 KALRADENYYKAQTHGKWPVKWYAPECI--NYYKFSSKSDVWSFGVLMWEAFSYGQKPYR 568 Query 817 SRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862 SE ++ R+ P+ CP ++ L + C TY+ RP F + Sbjct 569 GMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFTAV 616 >sp|P21804|FGFR1_CHICK Fibroblast growth factor receptor 1 OS=Gallus gallus OX=9031 GN=FGFR1 PE=2 SV=1 Length=819 Score = 160 bits (406), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 102/293 (35%), Positives = 149/293 (51%), Gaps = 38/293 (13%) Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956 + LGEG FG+V L D VAVK LK+D + S E+++++ + H Sbjct 480 KPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKH 539 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999 ++II G C G L +++EY G+LR+YL P + Sbjct 540 KNIINLLGACTQDG--PLYVIVEYASKGNLREYLQARRPPGMEYCYNPTRIPEEQLSFKD 597 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+ Sbjct 598 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDI-HHIDYYKKTT 656 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 +G PV W APE L + + + SDVWSFGV L+E+ T L G + Sbjct 657 NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGV 702 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L + Sbjct 703 PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 755 Score = 67.0 bits (162), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 62/257 (24%), Positives = 113/257 (44%), Gaps = 34/257 (13%) Query 638 RVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 +V +K+L D + D++ E + H ++ + G C + ++ EY G L Sbjct 508 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL 567 Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740 +L+ R +P +++K +V A Q+A + YL +K +H ++ RN+ Sbjct 568 REYLQARRPPGMEYCYNPTRIPEEQLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNV 627 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTA 794 L+ + +K++D G+ ++ R+P W+APE L + + Sbjct 628 LVTEDNV-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQS- 679 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATLTSQCLTYE 852 D W FG L EI G +P E + HR+ +PS +L + C Sbjct 680 -DVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAV 738 Query 853 PTQRPSFRTILRDLTRL 869 P+QRP+F+ ++ DL R+ Sbjct 739 PSQRPTFKQLVEDLDRI 755 >sp|P43405|KSYK_HUMAN Tyrosine-protein kinase SYK OS=Homo sapiens OX=9606 GN=SYK PE=1 SV=1 Length=635 Score = 158 bits (400), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 102/289 (35%), Positives = 144/289 (50%), Gaps = 27/289 (9%) Query 883 DSPASDPT------VFHKRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 +SP +DP V+ R L + D LG G+FG V Y V + +A Sbjct 349 ESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEA 408 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994 + P + E ++++ L + +I++ G CE + S LVME LG L YL ++ Sbjct 409 N-DPALKDELLAEANVMQQLDNPYIVRMIGICEAE---SWMLVMEMAELGPLNKYLQQNR 464 Query 995 -IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + ++ Q+ GM YL +++HRDLAARNVLL KI DFGL+KA+ Sbjct 465 HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN 524 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 YY+ + G PV WYAPEC+ YKF SDVWSFGV ++E ++ Q P Sbjct 525 YYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSY---GQKPYRG------ 575 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 M +T +LE+GER+ P CP E+Y LM CW + RP F Sbjct 576 -----MKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGF 619 Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 65/228 (29%), Positives = 108/228 (47%), Gaps = 25/228 (11%) Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 DP+ D LA A++M Q+ + ++ + G+C ++V E E GPL+ +L++ R Sbjct 410 DPALKDELLA---EANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNR- 464 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 HV + + Q++ + YLE N VH ++ RN+LL T + K+SD G+ Sbjct 465 HVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLV-------TQHYAKISDFGLS- 516 Query 765 GALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 AL +E + + W APEC+ S+ D W FG + E G+ P + Sbjct 517 KALRADENYYKAQTHGKWPVKWYAPECI--NYYKFSSKSDVWSFGVLMWEAFSYGQKPYR 574 Query 817 SRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862 SE ++ R+ P+ CP ++ L + C TY+ RP F + Sbjct 575 GMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAV 622 >sp|P00534|ERBB_ALV Tyrosine-protein kinase transforming protein erbB OS=Avian leukosis virus OX=11864 GN=V-ERBB PE=2 SV=2 Length=634 Score = 158 bits (400), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 104/307 (34%), Positives = 157/307 (51%), Gaps = 22/307 (7%) Query 864 RDLTRL-QPHNLADVLTVNPDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 R L RL Q L + LT + ++P + + + KK++ LG G FG V + P + Sbjct 97 RTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKVKVLGSGAFGTVYKGLWIPEGE 156 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VA+K L+ P+ E ++ ++ + H+ + G C ++QL+ + + Sbjct 157 KVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTS---TVQLITQLM 213 Query 982 PLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P G L DY+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI Sbjct 214 PYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLVHRDLAARNVLVKTPQHVKI 273 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLAK + + Y E G P+ W A E + + + SDVWS+GVT++EL+T Sbjct 274 TDFGLAKLLGADEKEYHA-EGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGS 332 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 GI + ++ +LE+GERLP+P C +VY +M CW +A R Sbjct 333 KPYD---------GIPASE-----ISSVLEKGERLPQPPICTIDVYMIMVKCWMIDADSR 378 Query 1160 PTFENLI 1166 P F LI Sbjct 379 PKFRELI 385 Score = 73.9 bits (180), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 52/221 (24%), Positives = 107/221 (48%), Gaps = 18/221 (8%) Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 + A +M+ V + H+ + G+C+ ++T+ + +G L ++R + ++ + + Sbjct 181 DEAYVMASVDNPHVCRLLGICLTSTVQ-LITQLMPYGCLLDYIREHKDNIGSQYLLNWCV 239 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE 774 Q+A ++YLE + LVH ++ RN+L+ T +K++D G+ LGA +E E Sbjct 240 QIAKGMNYLEERRLVHRDLAARNVLVK-------TPQHVKITDFGLAKLLGADEKEYHAE 292 Query 775 --RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 ++P W+A E + + + D W +G T+ E+ G P SE ++ Sbjct 293 GGKVPIKWMALESILHRIYTHQS--DVWSYGVTVWELMTFGSKPYDGIPASEISSVLEKG 350 Query 831 HRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869 RLP+P + + +C + RP FR ++ + +++ Sbjct 351 ERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIAEFSKM 391 >sp|Q95YD4|KIN32_CAEEL Inactive tyrosine-protein kinase kin-32 OS=Caenorhabditis elegans OX=6239 GN=kin-32 PE=1 SV=1 Length=867 Score = 160 bits (406), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 101/309 (33%), Positives = 157/309 (51%), Gaps = 26/309 (8%) Query 879 TVNPDSPAS-DPTVFHKRYLKKIRDL-GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC 936 T+ P +P + D + +R L +++L G G FG V Y VAVK K D Sbjct 347 TIRPKTPNNIDSNIRLRRELITLKELIGGGQFGNVYKAVYHDLEKDERIAVAVKVCKTDA 406 Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-- 994 P QE ++R H +II+ G C DQ + LV+E P G LR+YL + Sbjct 407 EPADTQLILQESSLMRNFRHSNIIQLIGVCVDQ---PMWLVLELAPKGELREYLQQEKDW 463 Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + L L LF QIC+ + YLH+ ++HRD+AARN+L+ + + VK+ DFGL++A+ Y Sbjct 464 LPLRILTLFCSQICDSLVYLHSTRFVHRDIAARNILVCSPQCVKLADFGLSRALDYDAVY 523 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 R G P+ W APE + +F ASDVW FGV ++E+ + +G+ Sbjct 524 TASR--GKLPIKWLAPESVNYRQFSMASDVWMFGVCMWEIFS---------------LGV 566 Query 1115 A-QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN-CWETEASFRPTFENLIPILKTV 1172 +T + +E+G R P P+KCP +Y+ +++ W E RPT + + I++ V Sbjct 567 KPWAGVTNSDVIMHIEQGSRPPCPEKCPTALYNFIRSKMWAIEPHKRPTVDQIYAIIEDV 626 Query 1173 HEKYQGQAP 1181 ++ P Sbjct 627 RQQIIQNIP 635 Score = 68.2 bits (165), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 69/242 (29%), Positives = 108/242 (45%), Gaps = 23/242 (10%) Query 632 DRGQELRVVLKV--LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 ++ + + V +KV D D L E +SLM H+++ + GVCV P +V E Sbjct 390 EKDERIAVAVKVCKTDAEPADTQLILQE-SSLMRNFRHSNIIQLIGVCVDQPM-WLVLEL 447 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 G L +L++E+ +P+ + Q+ +L YL + VH ++ RNIL+ Sbjct 448 APKGELREYLQQEKDWLPLRILTLFCSQICDSLVYLHSTRFVHRDIAARNILVC------ 501 Query 750 GTSP-FIKLSDPGVGLG----ALSREERVER-IPWLAPECLPGGANSLSTAMDKWGFGAT 803 SP +KL+D G+ A+ R + I WLAPE + S A D W FG Sbjct 502 --SPQCVKLADFGLSRALDYDAVYTASRGKLPIKWLAPESV--NYRQFSMASDVWMFGVC 557 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ--LATLTSQCLTYEPTQRPSFR 860 + EI G P + S+ ++ R P P CP + S+ EP +RP+ Sbjct 558 MWEIFSLGVKPWAGVTNSDVIMHIEQGSRPPCPEKCPTALYNFIRSKMWAIEPHKRPTVD 617 Query 861 TI 862 I Sbjct 618 QI 619 >sp|P00535|ERBB_AVIER Tyrosine-protein kinase transforming protein erbB OS=Avian erythroblastosis virus (strain ES4) OX=79685 GN=V-ERBB PE=3 SV=1 Length=604 Score = 158 bits (399), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 105/307 (34%), Positives = 159/307 (52%), Gaps = 22/307 (7%) Query 864 RDLTRL-QPHNLADVLTVNPDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 R L RL Q L + LT + ++P + + + KK++ LG G FG + + P + Sbjct 97 RTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKVKVLGSGAFGTIYKGLWIPEGE 156 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VA+K L+ P+ E ++ ++ + H+ + G C ++QL+ + + Sbjct 157 KVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLM 213 Query 982 PLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P G L DY+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI Sbjct 214 PYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLVHRDLAARNVLVKTPQHVKI 273 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLAK + + Y E G P+ W A E + + + SDVWS+GVT++EL+T Sbjct 274 TDFGLAKLLGADEKEYHA-EGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTF-- 330 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 S P GI + ++ +LE+GERLP+P C +VY +M CW +A R Sbjct 331 --GSKPYD-----GIPASE-----ISSVLEKGERLPQPPICTIDVYMIMVKCWMIDADSR 378 Query 1160 PTFENLI 1166 P F LI Sbjct 379 PKFRELI 385 Score = 73.9 bits (180), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 52/221 (24%), Positives = 107/221 (48%), Gaps = 18/221 (8%) Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 + A +M+ V + H+ + G+C+ ++T+ + +G L ++R + ++ + + Sbjct 181 DEAYVMASVDNPHVCRLLGICLTSTVQ-LITQLMPYGCLLDYIREHKDNIGSQYLLNWCV 239 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE 774 Q+A ++YLE + LVH ++ RN+L+ T +K++D G+ LGA +E E Sbjct 240 QIAKGMNYLEERRLVHRDLAARNVLVK-------TPQHVKITDFGLAKLLGADEKEYHAE 292 Query 775 --RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 ++P W+A E + + + D W +G T+ E+ G P SE ++ Sbjct 293 GGKVPIKWMALESILHRIYTHQS--DVWSYGVTVWELMTFGSKPYDGIPASEISSVLEKG 350 Query 831 HRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869 RLP+P + + +C + RP FR ++ + +++ Sbjct 351 ERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIAEFSKM 391 >sp|P50545|HCK_RAT Tyrosine-protein kinase HCK OS=Rattus norvegicus OX=10116 GN=Hck PE=1 SV=4 Length=524 Score = 156 bits (395), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 94/286 (33%), Positives = 144/286 (50%), Gaps = 29/286 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ + LG G FG+V + Y+ VAVK +K G + E ++++TL H Sbjct 260 LQMEKKLGAGQFGEVWMATYNKHTK-----VAVKTMKP--GSMSVEAFLAEANLMKTLQH 312 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAY 1013 + ++K ++ + +V E++ GSL D+L L +L+ F+ QI EGMA+ Sbjct 313 DKLVKLHAVV---SQEPIFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQISEGMAF 369 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W APE + Sbjct 370 IEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNE--YTAREGAKFPIKWTAPEAI 427 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 F SDVWSFG+ L E++T+ I M+ + LE G R Sbjct 428 NFGSFTIKSDVWSFGILLMEIVTYGR--------------IPYPGMSNPEVIRALEHGYR 473 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +PRPD CP E+Y +M CW+ RPTFE + +L + + Q Sbjct 474 MPRPDNCPEELYSIMIRCWKNRPEERPTFEYIQSVLDDFYTATESQ 519 Score = 85.9 bits (211), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 65/233 (28%), Positives = 110/233 (47%), Gaps = 19/233 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K + P + AF A+LM + H L +H V + P +VTE++ G L Sbjct 284 KVAVKTMKPGSMSVE-AFLAEANLMKTLQHDKLVKLHAVVSQEP-IFIVTEFMAKGSLLD 341 Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G P+ + + Q++ ++++E +N +H ++ NIL++ S K Sbjct 342 FLKSEEGSKQPLPKLIDFSAQISEGMAFIEQRNYIHRDLRAANILVS-------ASLVCK 394 Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ +RE I W APE + G S + D W FG L+EI G Sbjct 395 IADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFG--SFTIKSDVWSFGILLMEIVTYG 452 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTI 862 P S E + +R+P P +CP +L ++ +C P +RP+F I Sbjct 453 RIPYPGMSNPEVIRALEHGYRMPRPDNCPEELYSIMIRCWKNRPEERPTFEYI 505 >sp|P08103|HCK_MOUSE Tyrosine-protein kinase HCK OS=Mus musculus OX=10090 GN=Hck PE=1 SV=4 Length=524 Score = 156 bits (394), Expect = 8e-39, Method: Compositional matrix adjust. Identities = 93/286 (33%), Positives = 145/286 (51%), Gaps = 29/286 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ + LG G FG+V + Y+ VAVK +K G + E +++++L H Sbjct 260 LQMEKKLGAGQFGEVWMATYNKHTK-----VAVKTMKP--GSMSVEAFLAEANLMKSLQH 312 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAY 1013 + ++K ++ + +V E++ GSL D+L L +L+ F+ QI EGMA+ Sbjct 313 DKLVKLHAVV---SQEPIFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQISEGMAF 369 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W APE + Sbjct 370 IEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNE--YTAREGAKFPIKWTAPEAI 427 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 F SDVWSFG+ L E++T+ I M+ + LE G R Sbjct 428 NFGSFTIKSDVWSFGILLMEIVTYGR--------------IPYPGMSNPEVIRALEHGYR 473 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +PRPD CP E+Y++M CW+ RPTFE + +L + + Q Sbjct 474 MPRPDNCPEELYNIMIRCWKNRPEERPTFEYIQSVLDDFYTATESQ 519 Score = 85.9 bits (211), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 65/233 (28%), Positives = 109/233 (47%), Gaps = 19/233 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K + P + AF A+LM + H L +H V + P +VTE++ G L Sbjct 284 KVAVKTMKPGSMSVE-AFLAEANLMKSLQHDKLVKLHAVVSQEP-IFIVTEFMAKGSLLD 341 Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G P+ + + Q++ ++++E +N +H ++ NIL++ S K Sbjct 342 FLKSEEGSKQPLPKLIDFSAQISEGMAFIEQRNYIHRDLRAANILVS-------ASLVCK 394 Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ +RE I W APE + G S + D W FG L+EI G Sbjct 395 IADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFG--SFTIKSDVWSFGILLMEIVTYG 452 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTI 862 P S E + +R+P P +CP +L + +C P +RP+F I Sbjct 453 RIPYPGMSNPEVIRALEHGYRMPRPDNCPEELYNIMIRCWKNRPEERPTFEYI 505 >sp|P11362|FGFR1_HUMAN Fibroblast growth factor receptor 1 OS=Homo sapiens OX=9606 GN=FGFR1 PE=1 SV=3 Length=822 Score = 160 bits (404), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 102/293 (35%), Positives = 149/293 (51%), Gaps = 38/293 (13%) Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956 + LGEG FG+V L D VAVK LK+D + S E+++++ + H Sbjct 482 KPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKH 541 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999 ++II G C G L +++EY G+LR+YL P + Sbjct 542 KNIINLLGACTQDG--PLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKD 599 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+ Sbjct 600 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDI-HHIDYYKKTT 658 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 +G PV W APE L + + + SDVWSFGV L+E+ T L G + Sbjct 659 NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGV 704 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L + Sbjct 705 PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 757 Score = 66.6 bits (161), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 63/257 (25%), Positives = 112/257 (44%), Gaps = 34/257 (13%) Query 638 RVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 +V +K+L D + D++ E + H ++ + G C + ++ EY G L Sbjct 510 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL 569 Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740 +L+ R H P ++ K +V A Q+A + YL +K +H ++ RN+ Sbjct 570 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV 629 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTA 794 L+ + +K++D G+ ++ R+P W+APE L + + Sbjct 630 LVTEDNV-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQS- 681 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATLTSQCLTYE 852 D W FG L EI G +P E + HR+ +PS +L + C Sbjct 682 -DVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAV 740 Query 853 PTQRPSFRTILRDLTRL 869 P+QRP+F+ ++ DL R+ Sbjct 741 PSQRPTFKQLVEDLDRI 757 >sp|P22182|FGFR1_XENLA Fibroblast growth factor receptor 1 OS=Xenopus laevis OX=8355 GN=fgfr1 PE=1 SV=1 Length=812 Score = 160 bits (404), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 101/293 (34%), Positives = 148/293 (51%), Gaps = 38/293 (13%) Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956 + LGEG FG+V + D VAVK LK+D + S E+++++ + H Sbjct 476 KPLGEGCFGQVVMAEAIGLDKEKPNKVTKVAVKMLKSDASEKDLSDLISEMEMMKMIGKH 535 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999 ++II G C G L +++EY G+LR+YL P + Sbjct 536 KNIINLLGACTQDG--PLYVIVEYTSKGNLREYLRARRPPAMEYCYNPTCVPDQLLSFKD 593 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+ Sbjct 594 LVSCAYQVARGMDYLASKKCIHRDLAARNVLVTEDNIMKIADFGLARDI-HHIDYYKKTT 652 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 +G PV W APE L + + + SDVWSFGV L+E+ T L G + Sbjct 653 NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGV 698 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + L +LL+ G R+ +P C E+Y +MK+CW S RPTF L+ L + Sbjct 699 PMEELFKLLKEGHRMDKPTNCTNELYMMMKDCWHAMPSQRPTFNQLVEDLDRI 751 Score = 68.2 bits (165), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 64/257 (25%), Positives = 112/257 (44%), Gaps = 34/257 (13%) Query 638 RVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 +V +K+L D S D++ E + H ++ + G C + ++ EY G L Sbjct 504 KVAVKMLKSDASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYTSKGNL 563 Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740 +LR R VP +++K +V A Q+A + YL +K +H ++ RN+ Sbjct 564 REYLRARRPPAMEYCYNPTCVPDQLLSFKDLVSCAYQVARGMDYLASKKCIHRDLAARNV 623 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTA 794 L+ + +K++D G+ ++ R+P W+APE L + + Sbjct 624 LVTEDNI-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQS- 675 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATLTSQCLTYE 852 D W FG L EI G +P E + HR+ +P+ +L + C Sbjct 676 -DVWSFGVLLWEIFTLGGSPYPGVPMEELFKLLKEGHRMDKPTNCTNELYMMMKDCWHAM 734 Query 853 PTQRPSFRTILRDLTRL 869 P+QRP+F ++ DL R+ Sbjct 735 PSQRPTFNQLVEDLDRI 751 >sp|Q91009|NTRK1_CHICK High affinity nerve growth factor receptor (Fragment) OS=Gallus gallus OX=9031 GN=NTRK1 PE=1 SV=1 Length=778 Score = 159 bits (403), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 99/275 (36%), Positives = 143/275 (52%), Gaps = 35/275 (13%) Query 902 DLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +LGEG FGKV L C + +VAVKALK + R +++E ++L L HEHI+ Sbjct 498 ELGEGAFGKVFLAECSHLLPEQEKTLVAVKALK-EVTENARLDFQREAELLTVLQHEHIV 556 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----------------SIGLAQLLLFA 1004 K+ G C + L +V EY+ G L +L H + L+ +L A Sbjct 557 KFYGVCTEG--DPLIMVFEYMKHGDLNRFLRSHGPDAKILDQGQGQPCGQLTLSHMLQIA 614 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 QI GM YL + H++HRDLA RN L+ +D +VKIGDFG+++ + +YYRV P Sbjct 615 TQIASGMVYLASLHFVHRDLATRNCLVGHDLVVKIGDFGMSRDI-YSTDYYRVGGRTMLP 673 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 + W PE + KF SD+WSFGV L+E+ T+ + P Q++ Sbjct 674 IRWMPPESILYRKFTTESDIWSFGVVLWEIFTY---GKQP-----------WYQLSNTEA 719 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 E + +G L RP CP EVY +M++CW+ E R Sbjct 720 IECITQGRELERPRTCPSEVYDIMQSCWQREPQQR 754 Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 65/240 (27%), Positives = 103/240 (43%), Gaps = 31/240 (13%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K L + L F A L++ + H H+ +GVC G IMV EY++HG L+ + Sbjct 524 VAVKALKEVTENARLDFQREAELLTVLQHEHIVKFYGVCTEGDPLIMVFEYMKHGDLNRF 583 Query 699 LRRER--------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 LR G + ++ + +A Q+AS + YL + + VH ++ RN L+ Sbjct 584 LRSHGPDAKILDQGQGQPCGQLTLSHMLQIATQIASGMVYLASLHFVHRDLATRNCLV-- 641 Query 745 LGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKW 798 G +K+ D G+ S + + I W+ PE + +T D W Sbjct 642 -----GHDLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESIL--YRKFTTESDIW 694 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQR 856 FG L EI G+ P S +E + L P +CP ++ + C EP QR Sbjct 695 SFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRTCPSEVYDIMQSCWQREPQQR 754 >sp|Q00944|FAK1_CHICK Focal adhesion kinase 1 OS=Gallus gallus OX=9031 GN=PTK2 PE=1 SV=2 Length=1053 Score = 160 bits (406), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 102/275 (37%), Positives = 141/275 (51%), Gaps = 24/275 (9%) Query 901 RDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 R +GEG FG V Y P N VA+K K R + QE +R H HI Sbjct 426 RCIGEGQFGDVHQGIYMSPENPAMA--VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 483 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +K G E + ++ME LG LR +L + S+ LA L+L+A Q+ +AYL ++ Sbjct 484 VKLIGVI---TENPVWIIMELCTLGELRSFLQVRKFSLDLASLILYAYQLSTALAYLESK 540 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 ++HRD+AARNVL+ VK+GDFGL++ + E YY+ + G P+ W APE + + Sbjct 541 RFVHRDIAARNVLVSATDCVKLGDFGLSRYM-EDSTYYKASK-GKLPIKWMAPESINFRR 598 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F ASDVW FGV ++E+L H K ++IG +E GERLP P Sbjct 599 FTSASDVWMFGVCMWEILMH-GVKPFQGVKNNDVIG-------------RIENGERLPMP 644 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 CP +Y LM CW + S RP F L L T+ Sbjct 645 PNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679 Score = 88.2 bits (217), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 64/224 (29%), Positives = 106/224 (47%), Gaps = 21/224 (9%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F + A M Q H H+ + GV P I + E G L +L+ + + +A ++ Sbjct 468 FLQEALTMRQFDHPHIVKLIGVITENPVWI-IMELCTLGELRSFLQVRKFSLDLASLILY 526 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 A QL++AL+YLE+K VH ++ RN+L++ + +KL D GL + Sbjct 527 AYQLSTALAYLESKRFVHRDIAARNVLVS-------ATDCVKLGD--FGLSRYMEDSTYY 577 Query 775 R-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 + I W+APE + ++A D W FG + EI G P Q ++ Sbjct 578 KASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 635 Query 828 QRQHRLP-EPSC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + RLP P+C P L +L ++C Y+P++RP F + L+ + Sbjct 636 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679 >sp|P16092|FGFR1_MOUSE Fibroblast growth factor receptor 1 OS=Mus musculus OX=10090 GN=Fgfr1 PE=1 SV=2 Length=822 Score = 159 bits (403), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 102/293 (35%), Positives = 149/293 (51%), Gaps = 38/293 (13%) Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956 + LGEG FG+V L D VAVK LK+D + S E+++++ + H Sbjct 482 KPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKH 541 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999 ++II G C G L +++EY G+LR+YL P + Sbjct 542 KNIINLLGACTQDG--PLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKD 599 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+ Sbjct 600 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDI-HHIDYYKKTT 658 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 +G PV W APE L + + + SDVWSFGV L+E+ T L G + Sbjct 659 NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGV 704 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L + Sbjct 705 PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 757 Score = 66.6 bits (161), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 63/257 (25%), Positives = 112/257 (44%), Gaps = 34/257 (13%) Query 638 RVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 +V +K+L D + D++ E + H ++ + G C + ++ EY G L Sbjct 510 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL 569 Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740 +L+ R H P ++ K +V A Q+A + YL +K +H ++ RN+ Sbjct 570 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV 629 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTA 794 L+ + +K++D G+ ++ R+P W+APE L + + Sbjct 630 LVTEDNV-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQS- 681 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATLTSQCLTYE 852 D W FG L EI G +P E + HR+ +PS +L + C Sbjct 682 -DVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAV 740 Query 853 PTQRPSFRTILRDLTRL 869 P+QRP+F+ ++ DL R+ Sbjct 741 PSQRPTFKQLVEDLDRI 757 >sp|Q90Z00|FGR1A_DANRE Fibroblast growth factor receptor 1-A OS=Danio rerio OX=7955 GN=fgfr1a PE=1 SV=2 Length=810 Score = 159 bits (402), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 100/285 (35%), Positives = 148/285 (52%), Gaps = 38/285 (13%) Query 903 LGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEH 958 LGEG FG+V + D VAVK LK+D + S E+++++ + H++ Sbjct 471 LGEGCFGQVMMAEAMGMDKEKPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKN 530 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQLL 1001 II G C G L +++E+ G+LR+YL P ++ + L+ Sbjct 531 IINLLGACTQDG--PLYVIVEFAAKGNLREYLRVRRPPGMEYCYNPDQVPVENMSIKDLV 588 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+ +G Sbjct 589 SCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDI-HHIDYYKKTTNG 647 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 PV W APE L + + + SDVWSFGV L+E+ T L G + V Sbjct 648 RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGVPV 693 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L +LL+ G R+ RP C E+Y +M++CW S RPTF+ L+ Sbjct 694 EELFKLLKEGHRMDRPSTCTHELYMMMRDCWHAVPSQRPTFKQLV 738 Score = 67.4 bits (163), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 68/271 (25%), Positives = 115/271 (42%), Gaps = 37/271 (14%) Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680 MD E P +R ++ V + D + D++ E + H ++ + G C + Sbjct 487 MDKEKP-----NRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQD 541 Query 681 PENIMVTEYVEHGPLDVWLRRER----------GHVP---MAWKMVV--AQQLASALSYL 725 ++ E+ G L +LR R VP M+ K +V A Q+A + YL Sbjct 542 GPLYVIVEFAAKGNLREYLRVRRPPGMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYL 601 Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WL 779 +K +H ++ RN+L+ + +K++D G+ ++ R+P W+ Sbjct 602 ASKKCIHRDLAARNVLVTEDNV-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWM 654 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-C 838 APE L + + D W FG L EI G +P E + HR+ PS C Sbjct 655 APEALFDRIYTHQS--DVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDRPSTC 712 Query 839 P-QLATLTSQCLTYEPTQRPSFRTILRDLTR 868 +L + C P+QRP+F+ ++ DL R Sbjct 713 THELYMMMRDCWHAVPSQRPTFKQLVEDLDR 743 >sp|Q95M30|HCK_MACFA Tyrosine-protein kinase HCK OS=Macaca fascicularis OX=9541 GN=HCK PE=2 SV=3 Length=504 Score = 154 bits (390), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 93/286 (33%), Positives = 144/286 (50%), Gaps = 29/286 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 LK + LG G FG+V + Y+ VAVK +K G + E ++++TL H Sbjct 240 LKLEKKLGAGQFGEVWMATYNKHTK-----VAVKTMKP--GSMSVEAFLAEANLMKTLQH 292 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAY 1013 + ++K + + ++ E++ GSL D+L L +L+ F+ QI EGMA+ Sbjct 293 DKLVKLHAVVTKE---PIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAF 349 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ W APE + Sbjct 350 IEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNE--YTAREGAKFPIKWTAPEAI 407 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 SDVWSFG+ L E++T+ I M+ + LERG R Sbjct 408 NFGSSTIKSDVWSFGILLMEIVTYGR--------------IPYPGMSNPEVIRALERGYR 453 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +PRP+ CP E+Y++M CW+ RPTFE + +L + + Q Sbjct 454 MPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ 499 Score = 90.5 bits (223), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 65/233 (28%), Positives = 113/233 (48%), Gaps = 19/233 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K + P + AF A+LM + H L +H V + P I +TE++ G L Sbjct 264 KVAVKTMKPGSMSVE-AFLAEANLMKTLQHDKLVKLHAVVTKEPIYI-ITEFMAKGSLLD 321 Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ + G P+ + + Q+A ++++E +N +H ++ NIL++ S K Sbjct 322 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVS-------ASLVCK 374 Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ +RE I W APE + G++++ + D W FG L+EI G Sbjct 375 IADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSSTIKS--DVWSFGILLMEIVTYG 432 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTI 862 P S E +R +R+P P +CP +L + +C P +RP+F I Sbjct 433 RIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYI 485 >sp|P18460|FGFR3_CHICK Fibroblast growth factor receptor 3 OS=Gallus gallus OX=9031 GN=FGFR3 PE=2 SV=1 Length=806 Score = 158 bits (400), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 115/351 (33%), Positives = 167/351 (48%), Gaps = 39/351 (11%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT-VFHKRYLKKIRD 902 L Q ++ E + T L +TRL + + V+ DP + L + Sbjct 412 LKRQQVSLESNSSMNSNTPLVRITRLSSSDGPMLANVSELELPPDPKWELARSRLTLGKP 471 Query 903 LGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEH 958 LGEG FG+V + D VAVK LK D + S E+++++ + H++ Sbjct 472 LGEGCFGQVVMAEAIGIDKDKPNKAITVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 531 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQLL 1001 II G C G L +++EY G+LR+YL P + L+ Sbjct 532 IINLLGACTQDG--PLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKLPEEQLTFKDLV 589 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 A Q+ GM YL +Q IHRDLAARNVL+ D ++KI DFGLA+ V +YY+ +G Sbjct 590 SCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDV-HNIDYYKKTTNG 648 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 PV W APE L + + + SDVWSFGV L+E+ T L G + V Sbjct 649 RLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGIPV 694 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 L +LL+ G R+ +P C ++Y +M+ CW S RPTF+ L+ L V Sbjct 695 EELFKLLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRV 745 Score = 64.3 bits (155), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 65/262 (25%), Positives = 117/262 (45%), Gaps = 36/262 (14%) Query 634 GQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYV 690 + + V +K+L D + D++ E + H ++ + G C + GP ++V EY Sbjct 494 NKAITVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLV-EYA 552 Query 691 EHGPLDVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNV 735 G L +LR R +P + +K +V A Q+A + YL ++ +H ++ Sbjct 553 SKGNLREYLRARRPPGMDYSFDTCKLPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDL 612 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGAN 789 RN+L+ +K++D G+ + ++ R+P W+APE L Sbjct 613 AARNVLVTE-------DNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVY 665 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQ 847 + + D W FG L EI G +P E + HR+ +P+ C L + + Sbjct 666 THQS--DVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRE 723 Query 848 CLTYEPTQRPSFRTILRDLTRL 869 C P+QRP+F+ ++ DL R+ Sbjct 724 CWHAVPSQRPTFKQLVEDLDRV 745 >sp|Q91738|FAK1_XENLA Focal adhesion kinase 1 OS=Xenopus laevis OX=8355 GN=ptk2 PE=2 SV=2 Length=1068 Score = 159 bits (403), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 101/276 (37%), Positives = 144/276 (52%), Gaps = 26/276 (9%) Query 901 RDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 R +GEG FG V Y P N VA+K K R + QE +R H HI Sbjct 439 RCIGEGQFGDVHQGVYMSPENPAMA--VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI 496 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +K G E + ++ME LG LR +L ++S+ LA L+L++ Q+ +AYL ++ Sbjct 497 VKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYSYQLSTALAYLESK 553 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 ++HRD+AARNVL+ + VK+GDFGL++ + E YY+ + G P+ W APE + + Sbjct 554 RFVHRDIAARNVLVSSSDCVKLGDFGLSRYM-EDSTYYKASK-GKLPIKWMAPESINFRR 611 Query 1078 FYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 F ASDVW FGV ++E+L + Q K ++IG +E GERLP Sbjct 612 FTSASDVWMFGVCMWEILMYGVKPFQG--VKNNDVIG-------------RIENGERLPM 656 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P CP +Y LM CW + S RP F L L T+ Sbjct 657 PPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 692 Score = 87.8 bits (216), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 64/224 (29%), Positives = 107/224 (48%), Gaps = 21/224 (9%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F + A M Q H H+ + GV P I + E G L +L+ + + +A ++ Sbjct 481 FLQEALTMRQFDHPHIVKLIGVITENPVWI-IMELCTLGELRSFLQVRKYSLDLASLILY 539 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + QL++AL+YLE+K VH ++ RN+L++ +S +KL D GL + Sbjct 540 SYQLSTALAYLESKRFVHRDIAARNVLVS-------SSDCVKLGD--FGLSRYMEDSTYY 590 Query 775 R-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 + I W+APE + ++A D W FG + EI G P Q ++ Sbjct 591 KASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWEILMYGVKPFQGVKNNDVIGRI 648 Query 828 QRQHRLP-EPSC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + RLP P+C P L +L ++C Y+P++RP F + L+ + Sbjct 649 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 692 >sp|P42688|SRK2_SPOLA Tyrosine-protein kinase SRK2 (Fragment) OS=Spongilla lacustris OX=6055 GN=SRK2 PE=2 SV=1 Length=362 Score = 150 bits (380), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 110/328 (34%), Positives = 161/328 (49%), Gaps = 43/328 (13%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVN---PDSPASDPTV-----------FHKRYLKK 899 T+R F T L+DL + N +D L VN P P P + + + Sbjct 40 TRRAVFNT-LKDLVQYY-QNESDGLCVNLRQPCRPLERPQIDLSHKTKDMWEISRDSITL 97 Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 IR LG G FG+V ++ + VAVK LKA G + + E I++ L H + Sbjct 98 IRKLGAGQFGEVYQGLWNNSTP-----VAVKTLKA--GTMQPAAFLAEAQIMKKLRHPKL 150 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQ 1017 I+ C QGE + ++ E + GSL DYL + + L QL+ A Q+ GMAYL Sbjct 151 IQLYAVCT-QGE-PVYIITELMSKGSLLDYLQGEAGALKLPQLIDMAAQVAAGMAYLELH 208 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +YIHRDLAARN+L+ ++ + K+ DFGLA+ + Y E P+ W APE + Sbjct 209 NYIHRDLAARNILVGDNNICKVADFGLARLIVSDD--YNATEGAKFPIKWTAPEAALFNR 266 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFG+ + EL+T+ I M+ + + L++G R+P P Sbjct 267 FSIKSDVWSFGILITELVTYGR--------------IPYPGMSNAEVLQNLDKGYRMPCP 312 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165 P +Y +M +CW+ + RPTFE L Sbjct 313 VTTPESLYQIMLDCWKRNPADRPTFEAL 340 Score = 88.6 bits (218), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 104/421 (25%), Positives = 173/421 (41%), Gaps = 73/421 (17%) Query 471 YLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELG 530 +L+ S S P L++ Q D ++ R+RK +G F + F ++++L Sbjct 2 FLVRESESKPGDYSLSI----QDGDNVKHYRIRKL----DEGGFFITRRA-VFNTLKDLV 52 Query 531 AALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEIT 590 Q + C +LR+ C P +L S +T ++ ++S + IT Sbjct 53 QYYQN---ESDGLCVNLRQPCRPLERPQIDL--------SHKTKDMWEIS-----RDSIT 96 Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + LG G VY+G + + P V +K L Sbjct 97 LIRKLGAGQFGEVYQG---LWNNSTP----------------------VAVKTLKAGTMQ 131 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 A AF A +M ++ H L ++ VC +G ++TE + G L +L+ E G + + Sbjct 132 PA-AFLAEAQIMKKLRHPKLIQLYAVCTQGEPVYIITELMSKGSLLDYLQGEAGALKLPQ 190 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + +A Q+A+ ++YLE N +H ++ RNIL+ G + K++D G+ +S + Sbjct 191 LIDMAAQVAAGMAYLELHNYIHRDLAARNILV-------GDNNICKVADFGLARLIVSDD 243 Query 771 ERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 I W APE N S D W FG + E+ G P S +E Sbjct 244 YNATEGAKFPIKWTAPEA--ALFNRFSIKSDVWSFGILITELVTYGRIPYPGMSNAEVLQ 301 Query 826 FYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI---LRDLTRL---QPHNLADV 877 + +R+P P + P+ L + C P RP+F + L D L Q + ADV Sbjct 302 NLDKGYRMPCPVTTPESLYQIMLDCWKRNPADRPTFEALQWRLEDFFVLDAGQYQHAADV 361 Query 878 L 878 L Sbjct 362 L 362 >sp|Q09147|FGFR2_DROME Fibroblast growth factor receptor homolog 2 OS=Drosophila melanogaster OX=7227 GN=btl PE=2 SV=3 Length=1052 Score = 159 bits (402), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 100/292 (34%), Positives = 155/292 (53%), Gaps = 44/292 (15%) Query 903 LGEGHFGKVSLYCYD--PTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTL-YHEH 958 LGEG FG+V + + P + E +VAVK +K + + +E+++++ + H + Sbjct 718 LGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHIN 777 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------------------------ 994 II GCC G L +++EY P G+L+D+L ++ Sbjct 778 IINLLGCCSQGG--PLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQH 835 Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 +G +L FA QI GM YL ++ IHRDLAARNVL+ + ++KI DFGLA+ + + EY Sbjct 836 LGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIADFGLARDI-QDTEY 894 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 YR +G P+ W APE L+E K+ SDVWS+GV L+E++T+ D P + Sbjct 895 YRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQ----PYPHI----- 945 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 ++ L L G+R+ +P KC +Y +M+ CW E+ RPTF L+ Sbjct 946 ----LSAEELYSYLITGQRMEKPAKCSLNIYVVMRQCWHFESCARPTFAELV 993 Score = 57.0 bits (136), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 59/262 (23%), Positives = 106/262 (40%), Gaps = 44/262 (17%) Query 636 ELRVVLKVLDPSHHDIALA-FYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHG 693 E V +K++ H D +A +M + H ++ + G C +G ++ EY HG Sbjct 742 ETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHG 801 Query 694 PLDVWLRRERGHVP--------------------MAWKMVV--AQQLASALSYLENKNLV 731 L +L++ R P + K + A Q+A + YL ++ + Sbjct 802 NLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCI 861 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLP 785 H ++ RN+L++ +K++D G+ R+ R+P W+APE L Sbjct 862 HRDLAARNVLVS-------DGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQ 914 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY----QRQHRLPEPSCPQL 841 + D W +G L EI G+ P +E+ + Y QR + P + Sbjct 915 --EKKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEK-PAKCSLNI 971 Query 842 ATLTSQCLTYEPTQRPSFRTIL 863 + QC +E RP+F ++ Sbjct 972 YVVMRQCWHFESCARPTFAELV 993 >sp|O42127|FGFR3_XENLA Fibroblast growth factor receptor 3 OS=Xenopus laevis OX=8355 GN=fgfr3 PE=2 SV=1 Length=802 Score = 158 bits (399), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 102/293 (35%), Positives = 147/293 (50%), Gaps = 38/293 (13%) Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956 + LGEG FG+V + D VAVK LK D + S E+++++ + H Sbjct 466 KPLGEGCFGQVVMAEAIGIDKERPNKPATVAVKMLKDDATDKDLSDLVSEMEMMKMIGKH 525 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999 ++II G C G L +++EY GSLR+YL P + Sbjct 526 KNIINLLGACTQDG--PLYVLVEYASKGSLREYLKARRPPGMDYSFDACKIPAEQLTFKD 583 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 L+ A Q+ GM YL +Q IHRDLAARNVL+ +D ++KI DFGLA+ + +YY+ Sbjct 584 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDI-HNIDYYKKTT 642 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 +G PV W APE L + + + SDVWS+GV L+E+ T L G + Sbjct 643 NGRLPVKWMAPEALFDRIYTHHSDVWSYGVLLWEIFT--------------LGGSPYPGI 688 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 V L +LL+ G R+ +P C E+Y +M+ CW S RP F+ L+ L V Sbjct 689 PVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPAFKQLVEDLDRV 741 Score = 61.6 bits (148), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 70/284 (25%), Positives = 127/284 (45%), Gaps = 44/284 (15%) Query 639 VVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPL 695 V +K+L D + D++ E + H ++ + G C + GP ++V EY G L Sbjct 495 VAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLV-EYASKGSL 553 Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740 +L+ R +P + +K +V A Q+A + YL ++ +H ++ RN+ Sbjct 554 REYLKARRPPGMDYSFDACKIPAEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNV 613 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGANSLSTA 794 L+ + +K++D G+ + ++ R+P W+APE L + + Sbjct 614 LVTDDNV-------MKIADFGLARDIHNIDYYKKTTNGRLPVKWMAPEALFDRIYTHHS- 665 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYE 852 D W +G L EI G +P E + HR+ +P+ C +L + +C Sbjct 666 -DVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAV 724 Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896 P+QRP+F+ ++ DL R VLTV + D +V ++Y Sbjct 725 PSQRPAFKQLVEDLDR--------VLTVTSTNEYLDLSVAFEQY 760 >sp|P13388|XMRK_XIPMA Melanoma receptor tyrosine-protein kinase OS=Xiphophorus maculatus OX=8083 GN=xmrk PE=2 SV=2 Length=1167 Score = 159 bits (402), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 105/301 (35%), Positives = 154/301 (51%), Gaps = 21/301 (7%) Query 869 LQPHNLADVLTVNPDSPASD-PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 LQ L + LT + +P + + KK R LG G FG V ++P + V Sbjct 681 LQEKELVEPLTPSGQAPNQAFLRILKETEFKKDRVLGSGAFGTVYKGLWNPDGENIRIPV 740 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K L+ P+ E ++ ++ H H+ + G C ++QLV + +P G L Sbjct 741 AIKVLREATSPKVNQEVLDEAYVMASVDHPHVCRLLGICL---TSAVQLVTQLMPYGCLL 797 Query 988 DYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 DY+ +H I LL + QI +GM YL +H +HRDLAARNVLL N VKI DFGL+ Sbjct 798 DYVRQHQERICGQWLLNWCVQIAKGMNYLEERHLVHRDLAARNVLLKNPNHVKITDFGLS 857 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 K + + Y+ + G P+ W A E + ++ + + SDVWS+GVT++EL+T S P Sbjct 858 KLLTADEKEYQA-DGGKVPIKWMALESILQWTYTHQSDVWSYGVTVWELMTF----GSKP 912 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + IA +LE GERLP+P C EVY ++ CW + S RP F L Sbjct 913 YDGIPAKEIA----------SVLENGERLPQPPICTIEVYMIILKCWMIDPSSRPRFREL 962 Query 1166 I 1166 + Sbjct 963 V 963 Score = 75.9 bits (185), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 59/247 (24%), Positives = 118/247 (48%), Gaps = 21/247 (9%) Query 634 GQELR--VVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 G+ +R V +KVL + + + + A +M+ V H H+ + G+C+ +VT+ + Sbjct 733 GENIRIPVAIKVLREATSPKVNQEVLDEAYVMASVDHPHVCRLLGICLTSAVQ-LVTQLM 791 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 +G L ++R+ + + W + Q+A ++YLE ++LVH ++ RN+LL Sbjct 792 PYGCLLDYVRQHQERICGQWLLNWCVQIAKGMNYLEERHLVHRDLAARNVLLK------- 844 Query 751 TSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGATL 804 +K++D G+ L A +E + + I W+A E + + + D W +G T+ Sbjct 845 NPNHVKITDFGLSKLLTADEKEYQADGGKVPIKWMALESILQW--TYTHQSDVWSYGVTV 902 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTI 862 E+ G P E + RLP+P ++ + +C +P+ RP FR + Sbjct 903 WELMTFGSKPYDGIPAKEIASVLENGERLPQPPICTIEVYMIILKCWMIDPSSRPRFREL 962 Query 863 LRDLTRL 869 + + +++ Sbjct 963 VGEFSQM 969 >sp|P22607|FGFR3_HUMAN Fibroblast growth factor receptor 3 OS=Homo sapiens OX=9606 GN=FGFR3 PE=1 SV=1 Length=806 Score = 158 bits (399), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 102/293 (35%), Positives = 147/293 (50%), Gaps = 38/293 (13%) Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956 + LGEG FG+V + D VAVK LK D + S E+++++ + H Sbjct 476 KPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKH 535 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999 ++II G C G L +++EY G+LR++L P + Sbjct 536 KNIINLLGACTQGG--PLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKD 593 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 L+ A Q+ GM YL +Q IHRDLAARNVL+ D ++KI DFGLA+ V +YY+ Sbjct 594 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDV-HNLDYYKKTT 652 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 +G PV W APE L + + + SDVWSFGV L+E+ T L G + Sbjct 653 NGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGI 698 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 V L +LL+ G R+ +P C ++Y +M+ CW S RPTF+ L+ L V Sbjct 699 PVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRV 751 Score = 65.9 bits (159), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 64/265 (24%), Positives = 117/265 (44%), Gaps = 35/265 (13%) Query 631 RDRGQE-LRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 +DR + + V +K+L D + D++ E + H ++ + G C +G ++ Sbjct 496 KDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLV 555 Query 688 EYVEHGPLDVWLRRERG-------------HVPMAWKMVV--AQQLASALSYLENKNLVH 732 EY G L +LR R + +K +V A Q+A + YL ++ +H Sbjct 556 EYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIH 615 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPG 786 ++ RN+L+ + +K++D G+ + ++ R+P W+APE L Sbjct 616 RDLAARNVLVTEDNV-------MKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFD 668 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATL 844 + + D W FG L EI G +P E + HR+ +P+ C L + Sbjct 669 RVYTHQS--DVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMI 726 Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869 +C P+QRP+F+ ++ DL R+ Sbjct 727 MRECWHAAPSQRPTFKQLVEDLDRV 751 >sp|P18461|FGFR2_CHICK Fibroblast growth factor receptor 2 OS=Gallus gallus OX=9031 GN=FGFR2 PE=2 SV=1 Length=823 Score = 158 bits (399), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 104/311 (33%), Positives = 155/311 (50%), Gaps = 43/311 (14%) Query 892 FHKRYLKKIRDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 F + L + LGEG FG+V + D VAVK LK D + S E+ Sbjct 478 FPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKEAVTVAVKMLKDDATEKDLSDLVSEM 537 Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------------- 990 ++++ + H++II G C G L +++EY G+LR+YL Sbjct 538 EMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPPGMEYSFDINRV 595 Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 P + L+ Q+ GM YL +Q IHRDLAARNVL+ + ++KI DFGLA+ + Sbjct 596 PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDI-N 654 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 +YY+ +G PV W APE L + + + SDVWSFGV ++E+ T Sbjct 655 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT-------------- 700 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 L G + V L +LL+ G R+ +P C E+Y +M++CW+ S RPTF+ L+ L Sbjct 701 LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWQAVPSQRPTFKQLVEDLD 760 Query 1171 -----TVHEKY 1176 T +E+Y Sbjct 761 RILTLTTNEEY 771 Score = 71.2 bits (173), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 65/265 (25%), Positives = 119/265 (45%), Gaps = 35/265 (13%) Query 631 RDRGQE-LRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 +DR +E + V +K+L D + D++ E + H ++ + G C + ++ Sbjct 507 KDRPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIV 566 Query 688 EYVEHGPLDVWLRRER----------GHVP---MAWKMVVA--QQLASALSYLENKNLVH 732 EY G L +LR R VP M +K +V+ QLA + YL ++ +H Sbjct 567 EYASKGNLREYLRARRPPGMEYSFDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIH 626 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE--RIP--WLAPECLPG 786 ++ RN+L+ + +K++D G+ + + ++ R+P W+APE L Sbjct 627 RDLAARNVLVTENNV-------MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFD 679 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATL 844 + + D W FG + EI G +P E + HR+ +P+ +L + Sbjct 680 RVYTHQS--DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMM 737 Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869 C P+QRP+F+ ++ DL R+ Sbjct 738 MRDCWQAVPSQRPTFKQLVEDLDRI 762 >sp|Q9V9J3|SRC42_DROME Tyrosine-protein kinase Src42A OS=Drosophila melanogaster OX=7227 GN=Src42A PE=1 SV=1 Length=517 Score = 154 bits (389), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 100/274 (36%), Positives = 137/274 (50%), Gaps = 30/274 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 LK +R LG G FG V ++ T VA+K LK+ G + E I++ L H Sbjct 248 LKFVRKLGSGQFGDVWEGLWNNTTP-----VAIKTLKS--GTMDPKDFLAEAQIMKKLRH 300 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQICEGM 1011 +I+ C E+ + ++ E + GSL +YL S+ + L+ A QI GM Sbjct 301 TKLIQLYAVC--TVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGM 358 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 AYL +Q+YIHRDLAARNVL+ + +VKI DFGLA+ + E Y R P+ W APE Sbjct 359 AYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDE--YEARVGARFPIKWTAPE 416 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 KF SDVWSFG+ L EL+T+ I MT + +E G Sbjct 417 AANYSKFSIKSDVWSFGILLTELVTYGR--------------IPYPGMTNAEVLTQVEHG 462 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 R+P+P C +Y +M CW + RPTFE L Sbjct 463 YRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETL 496 Score = 91.7 bits (226), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 64/234 (27%), Positives = 112/234 (48%), Gaps = 23/234 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH---VPMAWK 711 F A +M ++ HT L ++ VC ++TE ++HG L +L+ G + M Sbjct 288 FLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTL 347 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771 + +A Q+A+ ++YLE++N +H ++ RN+L+ G +K++D GL L +E+ Sbjct 348 IDMAAQIAAGMAYLESQNYIHRDLAARNVLV-------GDGNIVKIAD--FGLARLIKED 398 Query 772 RVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 E I W APE + S D W FG L E+ G P + +E Sbjct 399 EYEARVGARFPIKWTAPEA--ANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVL 456 Query 825 HFYQRQHRLPE-PSC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 + +R+P+ P+C P+L + +C +P +RP+F T+ L + +D Sbjct 457 TQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDFYTSDQSD 510 >sp|Q90413|FGFR4_DANRE Fibroblast growth factor receptor 4 OS=Danio rerio OX=7955 GN=fgfr4 PE=1 SV=1 Length=922 Score = 158 bits (400), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 104/310 (34%), Positives = 156/310 (50%), Gaps = 42/310 (14%) Query 892 FHKRYLKKIRDLGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 F + L + LGEG FG+V Y + N VAVK LK D + + E+ Sbjct 573 FPRENLTLGKPLGEGCFGQVVRAEAYGINKENQDHMATVAVKMLKDDATDKDLADLISEM 632 Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------------- 990 ++++ + H++II G C G L +++EY GSLR+YL Sbjct 633 ELMKVMDKHKNIINLLGVCTQDG--PLYVLVEYASKGSLREYLRARRPPGMDYTFDVTKV 690 Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 P + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ V + Sbjct 691 PEEQLTFKDLVSCAYQVARGMEYLASKRCIHRDLAARNVLVTEDNVMKIADFGLARGVHQ 750 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 +YY+ +G PV W APE L + + + SDVWSFGV ++E+ T Sbjct 751 -IDYYKKTTNGRMPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT-------------- 795 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP--- 1167 L G + V L +LL+ G R+ +P C E+Y M+ CW + RPTF+ L+ Sbjct 796 LGGSPYPGIPVEELFKLLKEGHRMDKPSNCTHELYMKMRECWHAVPTQRPTFKQLVEELD 855 Query 1168 -ILKTVHEKY 1176 +L ++ ++Y Sbjct 856 RVLVSISDEY 865 Score = 71.6 bits (174), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 70/257 (27%), Positives = 116/257 (45%), Gaps = 36/257 (14%) Query 639 VVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPL 695 V +K+L D + D+A E + H ++ + GVC + GP ++V EY G L Sbjct 611 VAVKMLKDDATDKDLADLISEMELMKVMDKHKNIINLLGVCTQDGPLYVLV-EYASKGSL 669 Query 696 DVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNI 740 +LR R VP + +K +V A Q+A + YL +K +H ++ RN+ Sbjct 670 REYLRARRPPGMDYTFDVTKVPEEQLTFKDLVSCAYQVARGMEYLASKRCIHRDLAARNV 729 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTA 794 L+ +K++D G+ G ++ R+P W+APE L + + Sbjct 730 LVTE-------DNVMKIADFGLARGVHQIDYYKKTTNGRMPVKWMAPEALFDRVYTHQS- 781 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYE 852 D W FG + EI G +P E + HR+ +PS C +L +C Sbjct 782 -DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPSNCTHELYMKMRECWHAV 840 Query 853 PTQRPSFRTILRDLTRL 869 PTQRP+F+ ++ +L R+ Sbjct 841 PTQRPTFKQLVEELDRV 857 >sp|Q91147|FGFR2_NOTVI Fibroblast growth factor receptor 2 OS=Notophthalmus viridescens OX=8316 GN=FGFR2 PE=2 SV=1 Length=729 Score = 157 bits (396), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 112/343 (33%), Positives = 167/343 (49%), Gaps = 45/343 (13%) Query 862 ILRDLTRLQPHNLADVLT-VNPDSPASDPT-VFHKRYLKKIRDLGEGHFGKVSL---YCY 916 ++R TRL +N +L V+ DP + + L + LGEG FG+V + Sbjct 352 LVRITTRLSSNNDTHLLAGVSEYELPEDPKWEYPREKLTLGKPLGEGCFGQVVMAEAVGI 411 Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQ 975 D VAVK LK D + S E+++++ + H++II G C G L Sbjct 412 DKDRPKDAATVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLY 469 Query 976 LVMEYVPLGSLRDYL-----------------PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 +++EY G+LR+YL P + L+ Q+ GM YL +Q Sbjct 470 VIVEYASKGNLREYLRTRRPPGMEYSFDINRIPEEQMTFKDLVSCTYQLARGMEYLASQK 529 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRDLAARNVL+ ++KI DFGLA+ + +YY+ +G PV W APE L + + Sbjct 530 CIHRDLAARNVLVTETNVMKIADFGLARDI-NNIDYYKKTTNGRLPVKWMAPEALFDRVY 588 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 + SDVWSFGV ++E+ T L G + V L +LL+ G R+ +P Sbjct 589 THQSDVWSFGVLMWEIFT--------------LGGSPYPGIPVEELFKLLKEGHRMDKPG 634 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPIL-----KTVHEKY 1176 C E+Y +M +CW S RPTF+ L+ L +T +E+Y Sbjct 635 NCTNELYTMMTDCWRAVPSQRPTFKQLVEDLDRILTQTTNEEY 677 Score = 72.0 bits (175), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 65/265 (25%), Positives = 121/265 (46%), Gaps = 35/265 (13%) Query 631 RDRGQEL-RVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 +DR ++ V +K+L D + D++ E + H ++ + G C + ++ Sbjct 413 KDRPKDAATVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIV 472 Query 688 EYVEHGPLDVWLRRER----------GHVP---MAWKMVVA--QQLASALSYLENKNLVH 732 EY G L +LR R +P M +K +V+ QLA + YL ++ +H Sbjct 473 EYASKGNLREYLRTRRPPGMEYSFDINRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIH 532 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE--RIP--WLAPECLPG 786 ++ RN+L+ + +K++D G+ + + ++ R+P W+APE L Sbjct 533 RDLAARNVLVTETNV-------MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFD 585 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATL 844 + + D W FG + EI G +P E + HR+ +P +C +L T+ Sbjct 586 RVYTHQS--DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPGNCTNELYTM 643 Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869 + C P+QRP+F+ ++ DL R+ Sbjct 644 MTDCWRAVPSQRPTFKQLVEDLDRI 668 >sp|P43403|ZAP70_HUMAN Tyrosine-protein kinase ZAP-70 OS=Homo sapiens OX=9606 GN=ZAP70 PE=1 SV=1 Length=619 Score = 155 bits (393), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 114/333 (34%), Positives = 157/333 (47%), Gaps = 39/333 (12%) Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899 ++ TL S T EP R D R P + T +SP SDP + L Sbjct 283 RIDTLNSDGYTPEPA-----RITSPDKPRPMPMD-----TSVYESPYSDPEELKDKKLFL 332 Query 900 IRD--------LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 RD LG G+FG V Y VA+K LK +E I+ Sbjct 333 KRDNLLIADIELGCGNFGSVRQGVYRMRKKQID--VAIKVLKQGTEKADTEEMMREAQIM 390 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICE 1009 L + +I++ G C+ + +L LVME G L +L R I ++ + Q+ Sbjct 391 HQLDNPYIVRLIGVCQAE---ALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSM 447 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 GM YL ++++HRDLAARNVLL N KI DFGL+KA+ YY R G P+ WYA Sbjct 448 GMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYA 507 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PEC+ KF SDVWS+GVT++E L++ Q P K M + +E Sbjct 508 PECINFRKFSSRSDVWSYGVTMWEALSY---GQKPYKK-----------MKGPEVMAFIE 553 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 +G+R+ P +CP E+Y LM +CW + RP F Sbjct 554 QGKRMECPPECPPELYALMSDCWIYKWEDRPDF 586 Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 68/242 (28%), Positives = 110/242 (45%), Gaps = 20/242 (8%) Query 631 RDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 R R +++ V +KVL A +M Q+ + ++ + GVC + ++V E Sbjct 358 RMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVC-QAEALMLVMEM 416 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 GPL +L +R +P++ + Q++ + YLE KN VH ++ RN+LL Sbjct 417 AGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLV------ 470 Query 750 GTSPFIKLSDPGV--GLGA-----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 + K+SD G+ LGA +R + W APEC+ S+ D W +G Sbjct 471 -NRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECI--NFRKFSSRSDVWSYGV 527 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP-EPSC-PQLATLTSQCLTYEPTQRPSFR 860 T+ E G+ P + E F ++ R+ P C P+L L S C Y+ RP F Sbjct 528 TMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFL 587 Query 861 TI 862 T+ Sbjct 588 TV 589 >sp|Q91286|FGFR2_PLEWA Fibroblast growth factor receptor 2 OS=Pleurodeles waltl OX=8319 GN=FGFR2 PE=2 SV=1 Length=824 Score = 157 bits (398), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 113/347 (33%), Positives = 165/347 (48%), Gaps = 47/347 (14%) Query 857 PSFRTILRDLTRLQPHNLADVLTVN-PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL-- 913 P R R L+ H LA V P+ P + + + L + LGEG FG+V + Sbjct 440 PLVRITTRLLSNTDTHLLAGVSEYELPEDPKWE---YPRDKLTLGKPLGEGCFGQVVMAE 496 Query 914 -YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGE 971 D VAVK LK D + S E+++++ + H++II G C G Sbjct 497 AVGIDKDRPKDAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDG- 555 Query 972 KSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQLLLFAQQICEGMAYL 1014 L +++EY G+LR+YL P + L+ Q+ GM YL Sbjct 556 -PLYVIVEYASKGNLREYLRTRRPPGMEYSFDIFRIPEEQMTFKDLVSCTYQLARGMEYL 614 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 +Q IHRDLAARNVL+ ++KI DFGLA+ + +YY+ +G PV W APE L Sbjct 615 ASQKCIHRDLAARNVLVTETNVIKIADFGLARDI-NNIDYYKKTTNGRLPVKWMAPEALF 673 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + + SDVWSFGV ++E+ T L G + V L +LL+ G R+ Sbjct 674 DRVYTLQSDVWSFGVLMWEIFT--------------LGGSPYPGIPVEELFKLLKEGHRM 719 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL-----KTVHEKY 1176 +P C E+Y +M +CW S RPTF+ L+ L +T +E+Y Sbjct 720 VKPGNCTNELYTMMTDCWRAVPSQRPTFKQLVEDLDRILTQTTNEEY 766 Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 67/265 (25%), Positives = 123/265 (46%), Gaps = 35/265 (13%) Query 631 RDRGQE-LRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 +DR ++ + V +K+L D + D++ E + H ++ + G C + ++ Sbjct 502 KDRPKDAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIV 561 Query 688 EYVEHGPLDVWLRRERG----------HVP---MAWKMVVA--QQLASALSYLENKNLVH 732 EY G L +LR R +P M +K +V+ QLA + YL ++ +H Sbjct 562 EYASKGNLREYLRTRRPPGMEYSFDIFRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIH 621 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE--RIP--WLAPECLPG 786 ++ RN+L+ + IK++D G+ + + ++ R+P W+APE L Sbjct 622 RDLAARNVLVTETNV-------IKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFD 674 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATL 844 +L + D W FG + EI G +P E + HR+ +P +C +L T+ Sbjct 675 RVYTLQS--DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMVKPGNCTNELYTM 732 Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869 + C P+QRP+F+ ++ DL R+ Sbjct 733 MTDCWRAVPSQRPTFKQLVEDLDRI 757 >sp|P21802|FGFR2_HUMAN Fibroblast growth factor receptor 2 OS=Homo sapiens OX=9606 GN=FGFR2 PE=1 SV=1 Length=821 Score = 157 bits (397), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 104/311 (33%), Positives = 154/311 (50%), Gaps = 43/311 (14%) Query 892 FHKRYLKKIRDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 F + L + LGEG FG+V + D VAVK LK D + S E+ Sbjct 476 FPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEM 535 Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------------- 990 ++++ + H++II G C G L +++EY G+LR+YL Sbjct 536 EMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPPGMEYSYDINRV 593 Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 P + L+ Q+ GM YL +Q IHRDLAARNVL+ + ++KI DFGLA+ + Sbjct 594 PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDI-N 652 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 +YY+ +G PV W APE L + + + SDVWSFGV ++E+ T Sbjct 653 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT-------------- 698 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 L G + V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L Sbjct 699 LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLD 758 Query 1171 -----TVHEKY 1176 T +E+Y Sbjct 759 RILTLTTNEEY 769 Score = 69.3 bits (168), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 64/265 (24%), Positives = 119/265 (45%), Gaps = 35/265 (13%) Query 631 RDRGQE-LRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 +D+ +E + V +K+L D + D++ E + H ++ + G C + ++ Sbjct 505 KDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIV 564 Query 688 EYVEHGPLDVWLRRER----------GHVP---MAWKMVVA--QQLASALSYLENKNLVH 732 EY G L +LR R VP M +K +V+ QLA + YL ++ +H Sbjct 565 EYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIH 624 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE--RIP--WLAPECLPG 786 ++ RN+L+ + +K++D G+ + + ++ R+P W+APE L Sbjct 625 RDLAARNVLVTENNV-------MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFD 677 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATL 844 + + D W FG + EI G +P E + HR+ +P+ +L + Sbjct 678 RVYTHQS--DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMM 735 Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869 C P+QRP+F+ ++ DL R+ Sbjct 736 MRDCWHAVPSQRPTFKQLVEDLDRI 760 >sp|P07949|RET_HUMAN Proto-oncogene tyrosine-protein kinase receptor Ret OS=Homo sapiens OX=9606 GN=RET PE=1 SV=3 Length=1114 Score = 158 bits (400), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 106/310 (34%), Positives = 146/310 (47%), Gaps = 43/310 (14%) Query 892 FHKRYLKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 F ++ L + LGEG FGKV + VAVK LK + P E ++ Sbjct 719 FPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNV 778 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------------------- 990 L+ + H H+IK G C G L L++EY GSLR +L Sbjct 779 LKQVNHPHVIKLYGACSQDG--PLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSS 836 Query 991 -----PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 ++ + L+ FA QI +GM YL +HRDLAARN+L+ R +KI DFGL+ Sbjct 837 SLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLS 896 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + V E Y + R G PV W A E L ++ + SDVWSFGV L+E++T Sbjct 897 RDVYEEDSYVK-RSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVT--------- 946 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L G + RL LL+ G R+ RPD C E+Y LM CW+ E RP F ++ Sbjct 947 -----LGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 1001 Query 1166 IPILKTVHEK 1175 L+ + K Sbjct 1002 SKDLEKMMVK 1011 Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 64/241 (27%), Positives = 104/241 (43%), Gaps = 40/241 (17%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------------ 707 +++ QV+H H+ ++G C + +++ EY ++G L +LR R P Sbjct 777 NVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSS 836 Query 708 -----------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 M + A Q++ + YL LVH ++ RNIL +AEG +K Sbjct 837 SLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNIL-----VAEGRK--MK 889 Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +SD G+ + V+R + W+A E L + +T D W FG L EI Sbjct 890 ISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESL--FDHIYTTQSDVWSFGVLLWEIVTL 947 Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 G P P + + HR+ P+ ++ L QC EP +RP F I +DL + Sbjct 948 GGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEK 1007 Query 869 L 869 + Sbjct 1008 M 1008 >sp|P21803|FGFR2_MOUSE Fibroblast growth factor receptor 2 OS=Mus musculus OX=10090 GN=Fgfr2 PE=1 SV=4 Length=821 Score = 157 bits (397), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 104/311 (33%), Positives = 154/311 (50%), Gaps = 43/311 (14%) Query 892 FHKRYLKKIRDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 F + L + LGEG FG+V + D VAVK LK D + S E+ Sbjct 476 FPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEM 535 Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------------- 990 ++++ + H++II G C G L +++EY G+LR+YL Sbjct 536 EMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPPGMEYSYDINRV 593 Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 P + L+ Q+ GM YL +Q IHRDLAARNVL+ + ++KI DFGLA+ + Sbjct 594 PEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDI-N 652 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 +YY+ +G PV W APE L + + + SDVWSFGV ++E+ T Sbjct 653 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT-------------- 698 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 L G + V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L Sbjct 699 LGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLD 758 Query 1171 -----TVHEKY 1176 T +E+Y Sbjct 759 RILTLTTNEEY 769 Score = 68.9 bits (167), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 64/265 (24%), Positives = 119/265 (45%), Gaps = 35/265 (13%) Query 631 RDRGQE-LRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 +D+ +E + V +K+L D + D++ E + H ++ + G C + ++ Sbjct 505 KDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIV 564 Query 688 EYVEHGPLDVWLRRER----------GHVP---MAWKMVVA--QQLASALSYLENKNLVH 732 EY G L +LR R VP M +K +V+ QLA + YL ++ +H Sbjct 565 EYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIH 624 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE--RIP--WLAPECLPG 786 ++ RN+L+ + +K++D G+ + + ++ R+P W+APE L Sbjct 625 RDLAARNVLVTE-------NNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFD 677 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATL 844 + + D W FG + EI G +P E + HR+ +P+ +L + Sbjct 678 RVYTHQS--DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMM 735 Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869 C P+QRP+F+ ++ DL R+ Sbjct 736 MRDCWHAVPSQRPTFKQLVEDLDRI 760 >sp|Q00655|KSYK_PIG Tyrosine-protein kinase SYK OS=Sus scrofa OX=9823 GN=SYK PE=1 SV=1 Length=628 Score = 155 bits (391), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 101/289 (35%), Positives = 144/289 (50%), Gaps = 27/289 (9%) Query 883 DSPASDPT------VFHKRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 +SP +DP V+ R L + D LG G+FG V Y V + +A Sbjct 342 ESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEA 401 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994 + P + E ++++ L + +I++ G CE + S LVME LG L YL ++ Sbjct 402 N-DPALKDELLAEANVMQQLDNPYIVRMIGICEAE---SWMLVMEMAELGPLNKYLQQNR 457 Query 995 -IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + ++ Q+ GM YL +++HRDLAARNVLL KI DFGL+KA+ Sbjct 458 HVKDKNIIELVHQVSMGMKYLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN 517 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 YY+ + G PV WYAPEC+ YKF SDVWSFGV ++E ++ Q P Sbjct 518 YYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSY---GQKPYRG------ 568 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 M ++ +LE+GER+ P CP E+Y LM CW + RP F Sbjct 569 -----MKGSEVSAMLEKGERMGCPPGCPREMYELMTLCWTYDVENRPGF 612 Score = 87.0 bits (214), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 65/228 (29%), Positives = 107/228 (47%), Gaps = 25/228 (11%) Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 DP+ D LA A++M Q+ + ++ + G+C ++V E E GPL+ +L++ R Sbjct 403 DPALKDELLA---EANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNR- 457 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 HV + + Q++ + YLE N VH ++ RN+LL T + K+SD G+ Sbjct 458 HVKDKNIIELVHQVSMGMKYLEECNFVHRDLAARNVLLV-------TQHYAKISDFGLS- 509 Query 765 GALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 AL +E + + W APEC+ S+ D W FG + E G+ P + Sbjct 510 KALRADENYYKAQTHGKWPVKWYAPECI--NYYKFSSKSDVWSFGVLMWEAFSYGQKPYR 567 Query 817 SRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTI 862 SE ++ R+ P CP ++ L + C TY+ RP F + Sbjct 568 GMKGSEVSAMLEKGERMGCPPGCPREMYELMTLCWTYDVENRPGFVAV 615 >sp|Q03351|NTRK3_RAT NT-3 growth factor receptor OS=Rattus norvegicus OX=10116 GN=Ntrk3 PE=1 SV=2 Length=864 Score = 157 bits (397), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 114/334 (34%), Positives = 158/334 (47%), Gaps = 77/334 (23%) Query 894 KRYLKKIRDLGEGHFGKVSLY-CYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 +R + R+LGEG FGKV L CY+ PT D +VAVKALK D R +++E ++ Sbjct 535 RRDIVLKRELGEGAFGKVFLAECYNLSPTKDKM--LVAVKALK-DPTLAARKDFQREAEL 591 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------------- 994 L L HEHI+K+ G C D L +V EY+ G L +L H Sbjct 592 LTNLQHEHIVKFYGVCGDG--DPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKG 649 Query 995 -IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV----- 1048 +GL+Q+L A QI GM YL +QH++HRDLA RN L+ + LVKIGDFG+++ V Sbjct 650 ELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDY 709 Query 1049 ------------------------------PEGHEYYRVREDGDS---PVFWYAPECLKE 1075 P G+++ E G P+ W PE + Sbjct 710 YREGPYQKGPFSVSWQQQRLAASAASTLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMY 769 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+E+ T+ + P Q++ + E + +G L Sbjct 770 RKFTTESDVWSFGVILWEIFTY---GKQP-----------WFQLSNTEVIECITQGRVLE 815 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 RP CP EVY +M CW+ E R + + IL Sbjct 816 RPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 849 Score = 67.0 bits (162), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 72/305 (24%), Positives = 118/305 (39%), Gaps = 74/305 (24%) Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 L P +D+ + V +K L F A L++ + H H+ +GVC G IMV Sbjct 560 LSPTKDK---MLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMV 616 Query 687 TEYVEHGPLDVWL---------------RRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 EY++HG L+ +L R+ +G + ++ + +A Q+AS + YL +++ V Sbjct 617 FEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFV 676 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP---------- 777 H ++ RN L+ G + +K+ D G+ S RE ++ P Sbjct 677 HRDLATRNCLV-------GANLLVKIGDFGMSRDVYSTDYYREGPYQKGPFSVSWQQQRL 729 Query 778 -------------------------------WLAPECLPGGANSLSTAMDKWGFGATLLE 806 W+ PE + +T D W FG L E Sbjct 730 AASAASTLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGVILWE 787 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILR 864 I G+ P S +E + L P CP ++ + C EP QR + + I + Sbjct 788 IFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYK 847 Query 865 DLTRL 869 L L Sbjct 848 ILHAL 852 >sp|Q91288|FGFR4_PLEWA Fibroblast growth factor receptor 4 OS=Pleurodeles waltl OX=8319 GN=FGFR4 PE=2 SV=1 Length=822 Score = 157 bits (396), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 106/319 (33%), Positives = 156/319 (49%), Gaps = 42/319 (13%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADCGPQ 939 D P F + L + LGEG FG+V Y + VA+K +K + Sbjct 472 DLPLDSKWEFPRERLVLGKPLGEGCFGQVVRAEAYGINKDQPDKAITVAIKIVKDKGTDK 531 Query 940 HRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------- 990 S E+++++ + H++II G C G L +++EY G+LR++L Sbjct 532 ELSDLISEMELMKLMGKHKNIINLLGVCTQDG--PLYMIVEYASKGNLREFLRARRPPSP 589 Query 991 ---------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 P + L+ + Q+ GMAYL ++ IHRDLAARNVL+ + ++KI D Sbjct 590 DYTFDMTKVPEEQLSFQDLVSCSYQVARGMAYLESKRCIHRDLAARNVLVTGENVMKIAD 649 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLA+ V + +YY+ +G PV W APE L + + + SDVWSFGV +E+ T Sbjct 650 FGLARGVHD-IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLTWEIFT----- 703 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 L G + V L +LL G R+ +P C E+Y LM+ CW S RPT Sbjct 704 ---------LGGSPYPGIPVEELFKLLREGHRMDKPSNCTHELYMLMRECWHAAPSQRPT 754 Query 1162 FENLIP----ILKTVHEKY 1176 F+ L+ IL TV E+Y Sbjct 755 FKQLVETLDRILATVAEEY 773 Score = 69.7 bits (169), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 65/260 (25%), Positives = 116/260 (45%), Gaps = 34/260 (13%) Query 635 QELRVVLKVLDPSHHDIALA-FYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEH 692 + + V +K++ D L+ LM + H ++ + GVC + M+ EY Sbjct 515 KAITVAIKIVKDKGTDKELSDLISEMELMKLMGKHKNIINLLGVCTQDGPLYMIVEYASK 574 Query 693 GPLDVWLRRERGHVP-------------MAWKMVVA--QQLASALSYLENKNLVHGNVCG 737 G L +LR R P ++++ +V+ Q+A ++YLE+K +H ++ Sbjct 575 GNLREFLRARRPPSPDYTFDMTKVPEEQLSFQDLVSCSYQVARGMAYLESKRCIHRDLAA 634 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSL 791 RN+L+ + +K++D G+ G ++ R+P W+APE L + Sbjct 635 RNVLVTGENV-------MKIADFGLARGVHDIDYYKKTSNGRLPVKWMAPEALFDRVYTH 687 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCL 849 + D W FG EI G +P E + HR+ +PS C +L L +C Sbjct 688 QS--DVWSFGVLTWEIFTLGGSPYPGIPVEELFKLLREGHRMDKPSNCTHELYMLMRECW 745 Query 850 TYEPTQRPSFRTILRDLTRL 869 P+QRP+F+ ++ L R+ Sbjct 746 HAAPSQRPTFKQLVETLDRI 765 >sp|Q5RB22|ERBB3_PONAB Receptor tyrosine-protein kinase erbB-3 OS=Pongo abelii OX=9601 GN=ERBB3 PE=2 SV=1 Length=1342 Score = 158 bits (400), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 98/277 (35%), Positives = 148/277 (53%), Gaps = 20/277 (7%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 +F + LKK++ LG G FG V + P + V +K ++ G Q + Sbjct 703 IFKETELKKLKVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLA 762 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQIC 1008 + +L H HI++ G C SLQLV +Y+PLGSL D++ +H ++G LL + QI Sbjct 763 IGSLDHAHIVRLLGLCPG---SSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIA 819 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +GM YL +HR+LAARNVLL + V++ DFG+A +P + E +P+ W Sbjct 820 KGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDKQLLYSE-AKTPIKWM 878 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A E + K+ + SDVWS+GVT++EL+T + P L L + +LL Sbjct 879 ALESIHFGKYTHQSDVWSYGVTVWELMTF----GAEPYAGLRLA----------EVPDLL 924 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 E+GERL +P C +VY +M CW + + RPTF+ L Sbjct 925 EKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKEL 961 Score = 64.7 bits (156), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 73/298 (24%), Positives = 121/298 (41%), Gaps = 49/298 (16%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL- 644 + E+ +L LG G V++G EG E +P V +KV+ Sbjct 706 ETELKKLKVLGSGVFGTVHKGVWIPEG-----------ESIKIP---------VCIKVIE 745 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D S A + + + H H+ + G+C G +VT+Y+ G L +R+ RG Sbjct 746 DKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLC-PGSSLQLVTQYLPLGSLLDHVRQHRG 804 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEGTSPFIK 756 + + Q+A + YLE +VH N+ RN+LL A G+A+ P K Sbjct 805 ALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDK 864 Query 757 LSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 L E I W+A E + G + + D W +G T+ E+ G P Sbjct 865 ---------QLLYSEAKTPIKWMALESIHFGKYTHQS--DVWSYGVTVWELMTFGAEPYA 913 Query 817 SRSPSEKEHFYQRQHRLPEPSCPQLATL-----TSQCLTYEPTQRPSFRTILRDLTRL 869 +E ++ RL + PQ+ T+ +C + RP+F+ + + TR+ Sbjct 914 GLRLAEVPDLLEKGERLAQ---PQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRM 968 >sp|Q61851|FGFR3_MOUSE Fibroblast growth factor receptor 3 OS=Mus musculus OX=10090 GN=Fgfr3 PE=1 SV=1 Length=801 Score = 157 bits (396), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 101/293 (34%), Positives = 146/293 (50%), Gaps = 37/293 (13%) Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956 + LGEG FG+V + D VAVK LK D + S E+++++ + H Sbjct 470 KPLGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKH 529 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999 ++II G C G L +++EY G+LR++L P + Sbjct 530 KNIINLLGACTQGG--PLYVLVEYAAKGNLREFLRARRPPGMDYSFDACRLPEEQLTCKD 587 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 L+ A Q+ GM YL +Q IHRDLAARNVL+ D ++KI DFGLA+ V +YY+ Sbjct 588 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDV-HNLDYYKKTT 646 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 +G PV W APE L + + + SDVWSFGV L+E+ T S P EL Sbjct 647 NGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTPGGPSPYPGIPVEELF------- 699 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +LL+ G R+ +P C ++Y +M+ CW S RPTF+ L+ L + Sbjct 700 ------KLLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRI 746 Score = 62.0 bits (149), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 66/266 (25%), Positives = 118/266 (44%), Gaps = 36/266 (14%) Query 631 RDR-GQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 +DR + + V +K+L D + D++ E + H ++ + G C +G ++ Sbjct 490 KDRTAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLV 549 Query 688 EYVEHGPLDVWLRRER----------GHVP---MAWKMVV--AQQLASALSYLENKNLVH 732 EY G L +LR R +P + K +V A Q+A + YL ++ +H Sbjct 550 EYAAKGNLREFLRARRPPGMDYSFDACRLPEEQLTCKDLVSCAYQVARGMEYLASQKCIH 609 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPG 786 ++ RN+L+ + +K++D G+ + ++ R+P W+APE L Sbjct 610 RDLAARNVLVTEDNV-------MKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFD 662 Query 787 GANSLSTAMDKWGFGATLLEICF-DGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLAT 843 + + D W FG L EI G +P E + HR+ +P SC L Sbjct 663 RVYTHQS--DVWSFGVLLWEIFTPGGPSPYPGIPVEELFKLLKEGHRMDKPASCTHDLYM 720 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869 + +C P+QRP+F+ ++ DL R+ Sbjct 721 IMRECWHAVPSQRPTFKQLVEDLDRI 746 >sp|Q91285|FGFR1_PLEWA Fibroblast growth factor receptor 1 OS=Pleurodeles waltl OX=8319 GN=FGFR1 PE=2 SV=1 Length=816 Score = 156 bits (395), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 102/293 (35%), Positives = 150/293 (51%), Gaps = 38/293 (13%) Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956 + LGEG FG+V + D VAVK LK+D + S E+++++ + H Sbjct 478 KPLGEGCFGQVVMGEAIGLDKEKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKH 537 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------------PRHS----IGLAQ 999 ++II G C G L +++EY G+LR+YL P H + Sbjct 538 KNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPPGMEYCYNPIHVSKDMLSFKD 595 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+ Sbjct 596 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDSVMKIADFGLARDI-HHIDYYKKTT 654 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 +G PV W APE L + + + SDVWSFGV L+E+ T L G + Sbjct 655 NGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGV 700 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L + Sbjct 701 PVEELFKLLKEGHRMDKPGNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 753 Score = 68.2 bits (165), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 66/272 (24%), Positives = 117/272 (43%), Gaps = 37/272 (14%) Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680 +D E P +R ++ V + D + D++ E + H ++ + G C + Sbjct 496 LDKEKP-----NRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQD 550 Query 681 PENIMVTEYVEHGPLDVWLRRERG----------HVP---MAWKMVV--AQQLASALSYL 725 ++ EY G L +LR R HV +++K +V A Q+A + YL Sbjct 551 GPLYVIVEYASKGNLREYLRARRPPGMEYCYNPIHVSKDMLSFKDLVSCAYQVARGMEYL 610 Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WL 779 +K +H ++ RN+L+ +K++D G+ ++ R+P W+ Sbjct 611 ASKKCIHRDLAARNVLVTE-------DSVMKIADFGLARDIHHIDYYKKTTNGRLPVKWM 663 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838 APE L + + D W FG L EI G +P E + HR+ +P +C Sbjct 664 APEALFDRIYTHQS--DVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPGNC 721 Query 839 P-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 +L + C P+QRP+F+ ++ DL R+ Sbjct 722 TNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 753 >sp|Q62799|ERBB3_RAT Receptor tyrosine-protein kinase erbB-3 OS=Rattus norvegicus OX=10116 GN=Erbb3 PE=1 SV=3 Length=1339 Score = 157 bits (398), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 96/277 (35%), Positives = 148/277 (53%), Gaps = 20/277 (7%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 +F + L+K++ LG G FG V + P + V +K ++ G Q + Sbjct 701 IFKETELRKLKVLGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLA 760 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQIC 1008 + +L H HI++ G C SLQLV +Y+PLGSL D++ +H ++G LL + QI Sbjct 761 VGSLDHAHIVRLLGLCPG---SSLQLVTQYLPLGSLLDHVKQHRETLGPQLLLNWGVQIA 817 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +GM YL +HRDLA RNV+L + V++ DFG+A +P + + + +P+ W Sbjct 818 KGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADLLPPDDKQL-LHSEAKTPIKWM 876 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A E + K+ + SDVWS+GVT++EL+T + P L L I +LL Sbjct 877 ALESIHFGKYTHQSDVWSYGVTVWELMTF----GAEPYAGLRLAEIP----------DLL 922 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 E+GERL +P C +VY +M CW + + RPTF+ L Sbjct 923 EKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKEL 959 Score = 60.5 bits (145), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 77/332 (23%), Positives = 136/332 (41%), Gaps = 53/332 (16%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL- 644 + E+ +L LG G V++G EG E +P V +KV+ Sbjct 704 ETELRKLKVLGSGVFGTVHKGIWIPEG-----------ESIKIP---------VCIKVIE 743 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D S A + + + H H+ + G+C G +VT+Y+ G L +++ R Sbjct 744 DKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLC-PGSSLQLVTQYLPLGSLLDHVKQHRE 802 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEGTSPFIK 756 + + Q+A + YLE ++VH ++ RN++L A G+A+ P K Sbjct 803 TLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADLLPPDDK 862 Query 757 LSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 L E I W+A E + G + + D W +G T+ E+ G P Sbjct 863 ---------QLLHSEAKTPIKWMALESIHFGKYTHQS--DVWSYGVTVWELMTFGAEPYA 911 Query 817 SRSPSEKEHFYQRQHRLPEPSCPQLATL-----TSQCLTYEPTQRPSFRTILRDLTRLQ- 870 +E ++ RL + PQ+ T+ +C + RP+F+ + + TR+ Sbjct 912 GLRLAEIPDLLEKGERLAQ---PQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMAR 968 Query 871 --PHNLADVLTVNPDS-PASDPTVFHKRYLKK 899 P L P + PA++P+V + L++ Sbjct 969 DPPRYLVIKRASGPGTPPAAEPSVLTTKELQE 1000 >sp|Q24488|ROR1_DROME Tyrosine-protein kinase transmembrane receptor Ror OS=Drosophila melanogaster OX=7227 GN=Ror PE=1 SV=1 Length=685 Score = 155 bits (391), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 104/281 (37%), Positives = 150/281 (53%), Gaps = 24/281 (9%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + +LGEG FGKV N T VA+KALK + + + +K+EI+++ L H++I Sbjct 413 LEELGEGAFGKVYKGQLLQPNKTTI-TVAIKALKENASVKTQQDFKREIELISDLKHQNI 471 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQL--LLFAQQICEGMAY 1013 + G ++ + ++ EY+ G L ++L P L+QL L A QI EGM Y Sbjct 472 VCILGVVLNK--EPYCMLFEYMANGDLHEFLISNSPTEGKSLSQLEFLQIALQISEGMQY 529 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 L A HY+HRDLAARN L++ +VKI DFGL++ + +YYRV+ PV W E + Sbjct 530 LSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSS-DYYRVQSKSLLPVRWMPSESI 588 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 KF SDVWSFGV L+E+ ++ P F Q + ++R +L Sbjct 589 LYGKFTTESDVWSFGVVLWEIYSY---GMQPYYGFSN-----QEVINLIRSRQL------ 634 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 L P+ CP VY LM CW ++ RPTF ++ LKT HE Sbjct 635 LSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRLKTWHE 675 Score = 59.7 bits (143), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 69/289 (24%), Positives = 119/289 (41%), Gaps = 43/289 (15%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-D 645 +++ L LG+G VY+G+L L P + + V +K L + Sbjct 408 QDVEFLEELGEGAFGKVYKGQL------------------LQPNK---TTITVAIKALKE 446 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR---- 701 + F L+S + H ++ + GV + M+ EY+ +G L +L Sbjct 447 NASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSPT 506 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 E + + +A Q++ + YL + VH ++ RN L+ GL +K+SD G Sbjct 507 EGKSLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNE-GLV------VKISDFG 559 Query 762 VGLGALSRE-ERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 + S + RV+ + W+ E + G +T D W FG L EI G P Sbjct 560 LSRDIYSSDYYRVQSKSLLPVRWMPSESILYG--KFTTESDVWSFGVVLWEIYSYGMQPY 617 Query 816 QSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 S E + + + L P +CP + +L +C + +RP+F I Sbjct 618 YGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDI 666 >sp|Q64725|KSYK_RAT Tyrosine-protein kinase SYK OS=Rattus norvegicus OX=10116 GN=Syk PE=1 SV=1 Length=629 Score = 154 bits (389), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 101/289 (35%), Positives = 143/289 (49%), Gaps = 27/289 (9%) Query 883 DSPASDPT------VFHKRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 +SP +DP V+ R L + D LG G+FG V Y V + +A Sbjct 343 ESPYADPEEIRPKEVYLDRKLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEA 402 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994 + P + E ++++ L + +I++ G CE + S LVME G L YL ++ Sbjct 403 N-DPALKDELLAEANVMQQLDNPYIVRMIGICEAE---SWMLVMEMAAWGPLNKYLQQNR 458 Query 995 -IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 I ++ Q+ GM YL +++HRDLAARNVLL KI DFGL+KA+ Sbjct 459 HIKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADEN 518 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 YY+ + G PV WYAPEC+ +KF SDVWSFGV ++E ++ Q P Sbjct 519 YYKAQTHGKWPVKWYAPECINYFKFSSKSDVWSFGVLMWEAFSY---GQKPYRG------ 569 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 M +T +LE+GER+ P CP E+Y LM CW + RP F Sbjct 570 -----MKGSEVTAMLEKGERMGCPPGCPREMYDLMFLCWTYDVENRPGF 613 Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 63/228 (28%), Positives = 105/228 (46%), Gaps = 25/228 (11%) Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 DP+ D LA A++M Q+ + ++ + G+C ++V E GPL+ +L++ R Sbjct 404 DPALKDELLA---EANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAAWGPLNKYLQQNR- 458 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 H+ + + Q++ + YLE N VH ++ RN+LL T + K+SD G+ Sbjct 459 HIKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLV-------TQHYAKISDFGLS- 510 Query 765 GALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 AL +E + + W APEC+ S+ D W FG + E G+ P + Sbjct 511 KALRADENYYKAQTHGKWPVKWYAPECI--NYFKFSSKSDVWSFGVLMWEAFSYGQKPYR 568 Query 817 SRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTI 862 SE ++ R+ P CP ++ L C TY+ RP F + Sbjct 569 GMKGSEVTAMLEKGERMGCPPGCPREMYDLMFLCWTYDVENRPGFAAV 616 >sp|Q03364|FGFR2_XENLA Fibroblast growth factor receptor 2 OS=Xenopus laevis OX=8355 GN=fgfr2 PE=2 SV=1 Length=813 Score = 156 bits (394), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 104/311 (33%), Positives = 154/311 (50%), Gaps = 43/311 (14%) Query 892 FHKRYLKKIRDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 F + L + LGEG FG+V + D VAVK LK + + + E+ Sbjct 466 FSRDKLTLGKPLGEGCFGQVVMAEALGIDKERPKESVTVAVKMLKDNATEKDLADLVSEM 525 Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------------- 990 ++++ + H++II G C G +L +++EY G+LR YL Sbjct 526 EMMKMIGKHKNIINLLGACTQGG--TLYVIVEYAAKGNLRQYLRARRPLEMEYSFDVTRV 583 Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 P + L+ QI GM YL +Q IHRDLAARNVL+ + ++KI DFGLA+ V Sbjct 584 PDEQMTFKDLVSCTYQIARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDV-N 642 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 +YY+ +G PV W APE L + + + SDVWSFGV ++E+ T Sbjct 643 NIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT-------------- 688 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 L G + V L +LL+ G R+ +P C E+Y +M++CW S RPTF+ L+ L Sbjct 689 LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAIPSHRPTFKQLVEDLD 748 Query 1171 -----TVHEKY 1176 T +E+Y Sbjct 749 RILTLTTNEEY 759 Score = 67.8 bits (164), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 61/260 (23%), Positives = 114/260 (44%), Gaps = 34/260 (13%) Query 635 QELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 + + V +K+L + + D+A E + H ++ + G C +G ++ EY Sbjct 500 ESVTVAVKMLKDNATEKDLADLVSEMEMMKMIGKHKNIINLLGACTQGGTLYVIVEYAAK 559 Query 693 GPLDVWLRRER----------GHVP---MAWKMVVA--QQLASALSYLENKNLVHGNVCG 737 G L +LR R VP M +K +V+ Q+A + YL ++ +H ++ Sbjct 560 GNLRQYLRARRPLEMEYSFDVTRVPDEQMTFKDLVSCTYQIARGMEYLASQKCIHRDLAA 619 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGANSL 791 RN+L+ + +K++D G+ + ++ R+P W+APE L + Sbjct 620 RNVLVTENNV-------MKIADFGLARDVNNIDYYKKTSNGRLPVKWMAPEALFDRVYTH 672 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATLTSQCL 849 + D W FG + EI G +P E + HR+ +P+ +L + C Sbjct 673 QS--DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCW 730 Query 850 TYEPTQRPSFRTILRDLTRL 869 P+ RP+F+ ++ DL R+ Sbjct 731 HAIPSHRPTFKQLVEDLDRI 750 >sp|P21860|ERBB3_HUMAN Receptor tyrosine-protein kinase erbB-3 OS=Homo sapiens OX=9606 GN=ERBB3 PE=1 SV=1 Length=1342 Score = 157 bits (397), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 97/277 (35%), Positives = 148/277 (53%), Gaps = 20/277 (7%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 +F + L+K++ LG G FG V + P + V +K ++ G Q + Sbjct 703 IFKETELRKLKVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLA 762 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQIC 1008 + +L H HI++ G C SLQLV +Y+PLGSL D++ +H ++G LL + QI Sbjct 763 IGSLDHAHIVRLLGLCPG---SSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIA 819 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +GM YL +HR+LAARNVLL + V++ DFG+A +P + E +P+ W Sbjct 820 KGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDKQLLYSE-AKTPIKWM 878 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A E + K+ + SDVWS+GVT++EL+T + P L L + +LL Sbjct 879 ALESIHFGKYTHQSDVWSYGVTVWELMTF----GAEPYAGLRLA----------EVPDLL 924 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 E+GERL +P C +VY +M CW + + RPTF+ L Sbjct 925 EKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKEL 961 Score = 64.3 bits (155), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 73/298 (24%), Positives = 121/298 (41%), Gaps = 49/298 (16%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL- 644 + E+ +L LG G V++G EG E +P V +KV+ Sbjct 706 ETELRKLKVLGSGVFGTVHKGVWIPEG-----------ESIKIP---------VCIKVIE 745 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D S A + + + H H+ + G+C G +VT+Y+ G L +R+ RG Sbjct 746 DKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLC-PGSSLQLVTQYLPLGSLLDHVRQHRG 804 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEGTSPFIK 756 + + Q+A + YLE +VH N+ RN+LL A G+A+ P K Sbjct 805 ALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDK 864 Query 757 LSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 L E I W+A E + G + + D W +G T+ E+ G P Sbjct 865 ---------QLLYSEAKTPIKWMALESIHFGKYTHQS--DVWSYGVTVWELMTFGAEPYA 913 Query 817 SRSPSEKEHFYQRQHRLPEPSCPQLATL-----TSQCLTYEPTQRPSFRTILRDLTRL 869 +E ++ RL + PQ+ T+ +C + RP+F+ + + TR+ Sbjct 914 GLRLAEVPDLLEKGERLAQ---PQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRM 968 >sp|Q61526|ERBB3_MOUSE Receptor tyrosine-protein kinase erbB-3 OS=Mus musculus OX=10090 GN=Erbb3 PE=1 SV=2 Length=1339 Score = 157 bits (397), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 96/277 (35%), Positives = 148/277 (53%), Gaps = 20/277 (7%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 +F + L+K++ LG G FG V + P + V +K ++ G Q + Sbjct 701 IFKETELRKLKVLGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLA 760 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQIC 1008 + +L H HI++ G C SLQLV +Y+PLGSL D++ +H ++G LL + QI Sbjct 761 VGSLDHAHIVRLLGLCPG---SSLQLVTQYLPLGSLLDHVRQHRETLGPQLLLNWGVQIA 817 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +GM YL +HRDLA RNV+L + V++ DFG+A +P + + + +P+ W Sbjct 818 KGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADLLPPDDKQL-LHSEAKTPIKWM 876 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A E + K+ + SDVWS+GVT++EL+T + P L L I +LL Sbjct 877 ALESIHFGKYTHQSDVWSYGVTVWELMTF----GAEPYAGLRLAEIP----------DLL 922 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 E+GERL +P C +VY +M CW + + RPTF+ L Sbjct 923 EKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKEL 959 Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 77/331 (23%), Positives = 133/331 (40%), Gaps = 53/331 (16%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL- 644 + E+ +L LG G V++G EG E +P V +KV+ Sbjct 704 ETELRKLKVLGSGVFGTVHKGIWIPEG-----------ESIKIP---------VCIKVIE 743 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D S A + + + H H+ + G+C G +VT+Y+ G L +R+ R Sbjct 744 DKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLC-PGSSLQLVTQYLPLGSLLDHVRQHRE 802 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEGTSPFIK 756 + + Q+A + YLE ++VH ++ RN++L A G+A+ P K Sbjct 803 TLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVMLKSPSQVQVADFGVADLLPPDDK 862 Query 757 LSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 L E I W+A E + G + + D W +G T+ E+ G P Sbjct 863 ---------QLLHSEAKTPIKWMALESIHFGKYTHQS--DVWSYGVTVWELMTFGAEPYA 911 Query 817 SRSPSEKEHFYQRQHRLPEPSCPQLATL-----TSQCLTYEPTQRPSFRTILRDLTRLQ- 870 +E ++ RL + PQ+ T+ +C + RP+F+ + + TR+ Sbjct 912 GLRLAEIPDLLEKGERLAQ---PQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMAR 968 Query 871 --PHNLADVLTVNPD-SPASDPTVFHKRYLK 898 P L P PA++P+ + L+ Sbjct 969 DPPRYLVIKRASGPGIPPAAEPSALSTKELQ 999 >sp|P55245|EGFR_MACMU Epidermal growth factor receptor OS=Macaca mulatta OX=9544 GN=EGFR PE=2 SV=2 Length=1210 Score = 157 bits (396), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 109/308 (35%), Positives = 160/308 (52%), Gaps = 24/308 (8%) Query 864 RDLTRL-QPHNLADVLTVNPDSPASDPT-VFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 R L RL Q L + LT + ++P + + KKI+ LG G FG V + P + Sbjct 677 RTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGE 736 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VA+K L+ P+ E ++ ++ + H+ + G C ++QL+ + + Sbjct 737 KVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLM 793 Query 982 PLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P G L DY+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI Sbjct 794 PFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKI 853 Query 1040 GDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 DFGLAK + E EY+ E G P+ W A E + + + SDVWS+GVT++EL+T Sbjct 854 TDFGLAKLLGAEEKEYH--AEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTF- 910 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 S P GI + ++ +LE+GERLP+P C +VY +M CW +A Sbjct 911 ---GSKPYD-----GIPASE-----ISSILEKGERLPQPPICTIDVYMIMVKCWMIDADS 957 Query 1159 RPTFENLI 1166 RP F LI Sbjct 958 RPKFRELI 965 Score = 72.0 bits (175), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 52/221 (24%), Positives = 105/221 (48%), Gaps = 18/221 (8%) Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 + A +M+ V + H+ + G+C+ ++T+ + G L ++R + ++ + + Sbjct 761 DEAYVMASVDNPHVCRLLGICLTSTVQ-LITQLMPFGCLLDYVREHKDNIGSQYLLNWCV 819 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE 774 Q+A ++YLE++ LVH ++ RN+L+ T +K++D G+ LGA +E E Sbjct 820 QIAKGMNYLEDRRLVHRDLAARNVLVK-------TPQHVKITDFGLAKLLGAEEKEYHAE 872 Query 775 R----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 I W+A E + + + D W +G T+ E+ G P SE ++ Sbjct 873 GGKVPIKWMALESILHRIYTHQS--DVWSYGVTVWELMTFGSKPYDGIPASEISSILEKG 930 Query 831 HRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869 RLP+P + + +C + RP FR ++ + +++ Sbjct 931 ERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKM 971 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens OX=9606 GN=EGFR PE=1 SV=2 Length=1210 Score = 157 bits (396), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 109/308 (35%), Positives = 160/308 (52%), Gaps = 24/308 (8%) Query 864 RDLTRL-QPHNLADVLTVNPDSPASDPT-VFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 R L RL Q L + LT + ++P + + KKI+ LG G FG V + P + Sbjct 677 RTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGE 736 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VA+K L+ P+ E ++ ++ + H+ + G C ++QL+ + + Sbjct 737 KVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLM 793 Query 982 PLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P G L DY+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI Sbjct 794 PFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKI 853 Query 1040 GDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 DFGLAK + E EY+ E G P+ W A E + + + SDVWS+GVT++EL+T Sbjct 854 TDFGLAKLLGAEEKEYH--AEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTF- 910 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 S P GI + ++ +LE+GERLP+P C +VY +M CW +A Sbjct 911 ---GSKPYD-----GIPASE-----ISSILEKGERLPQPPICTIDVYMIMVKCWMIDADS 957 Query 1159 RPTFENLI 1166 RP F LI Sbjct 958 RPKFRELI 965 Score = 71.6 bits (174), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 52/221 (24%), Positives = 105/221 (48%), Gaps = 18/221 (8%) Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 + A +M+ V + H+ + G+C+ ++T+ + G L ++R + ++ + + Sbjct 761 DEAYVMASVDNPHVCRLLGICLTSTVQ-LITQLMPFGCLLDYVREHKDNIGSQYLLNWCV 819 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE 774 Q+A ++YLE++ LVH ++ RN+L+ T +K++D G+ LGA +E E Sbjct 820 QIAKGMNYLEDRRLVHRDLAARNVLVK-------TPQHVKITDFGLAKLLGAEEKEYHAE 872 Query 775 R----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 I W+A E + + + D W +G T+ E+ G P SE ++ Sbjct 873 GGKVPIKWMALESILHRIYTHQS--DVWSYGVTVWELMTFGSKPYDGIPASEISSILEKG 930 Query 831 HRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869 RLP+P + + +C + RP FR ++ + +++ Sbjct 931 ERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKM 971 >sp|Q8JG38|FGFR2_DANRE Fibroblast growth factor receptor 2 OS=Danio rerio OX=7955 GN=fgfr2 PE=1 SV=1 Length=817 Score = 155 bits (393), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 104/302 (34%), Positives = 153/302 (51%), Gaps = 38/302 (13%) Query 892 FHKRYLKKIRDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 F + L + LGEG FG+V + D VAVK LK D + S E+ Sbjct 472 FSRDKLTLGKPLGEGCFGQVVMAEALGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEM 531 Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-------RHSIGLAQ- 999 ++++ + H++II G C G L +++EY G+LR+YL +S +A+ Sbjct 532 EMMKMIGRHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPPGMEYSYDIARV 589 Query 1000 ---------LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 L+ Q+ GM YL +Q IHRDLAARNVL+ ++KI DFGLA+ V Sbjct 590 SDEPLTFKDLVSCTYQVARGMEYLASQKCIHRDLAARNVLVTESNVMKIADFGLARDV-H 648 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 +YY+ +G PV W APE L + + + SDVWSFGV ++E+ T Sbjct 649 NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT-------------- 694 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 L G + V L +LL+ G R+ +P C E+Y +MK+CW +S RPTF+ L+ L Sbjct 695 LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMKDCWHAISSHRPTFKQLVEDLD 754 Query 1171 TV 1172 + Sbjct 755 RI 756 Score = 63.9 bits (154), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 60/265 (23%), Positives = 115/265 (43%), Gaps = 35/265 (13%) Query 631 RDRGQE-LRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 +D+ +E + V +K+L D + D++ E + H ++ + G C + ++ Sbjct 501 KDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGRHKNIINLLGACTQDGPLYVIV 560 Query 688 EYVEHGPLDVWLRRER-------------GHVPMAWKMVVA--QQLASALSYLENKNLVH 732 EY G L +LR R P+ +K +V+ Q+A + YL ++ +H Sbjct 561 EYASKGNLREYLRARRPPGMEYSYDIARVSDEPLTFKDLVSCTYQVARGMEYLASQKCIH 620 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPG 786 ++ RN+L+ S +K++D G+ + ++ R+P W+APE L Sbjct 621 RDLAARNVLVTE-------SNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFD 673 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--CPQLATL 844 + + D W FG + EI G +P E + HR+ +P+ +L + Sbjct 674 RVYTHQS--DVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMM 731 Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869 C + RP+F+ ++ DL R+ Sbjct 732 MKDCWHAISSHRPTFKQLVEDLDRI 756 >sp|Q01279|EGFR_MOUSE Epidermal growth factor receptor OS=Mus musculus OX=10090 GN=Egfr PE=1 SV=1 Length=1210 Score = 156 bits (395), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 109/308 (35%), Positives = 160/308 (52%), Gaps = 24/308 (8%) Query 864 RDLTRL-QPHNLADVLTVNPDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 R L RL Q L + LT + ++P + + + KKI+ LG G FG V + P + Sbjct 679 RTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGE 738 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VA+K L+ P+ E ++ ++ + H+ + G C ++QL+ + + Sbjct 739 KVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICL---TSTVQLITQLM 795 Query 982 PLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P G L DY+ H +IG LL + QI +GM YL + +HRDLAARNVL+ + VKI Sbjct 796 PYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKI 855 Query 1040 GDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 DFGLAK + E EY+ E G P+ W A E + + + SDVWS+GVT++EL+T Sbjct 856 TDFGLAKLLGAEEKEYH--AEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTF- 912 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 S P GI ++ +LE+GERLP+P C +VY +M CW +A Sbjct 913 ---GSKPYD-----GIPASD-----ISSILEKGERLPQPPICTIDVYMIMVKCWMIDADS 959 Query 1159 RPTFENLI 1166 RP F LI Sbjct 960 RPKFRELI 967 Score = 72.4 bits (176), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 51/221 (23%), Positives = 105/221 (48%), Gaps = 18/221 (8%) Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 + A +M+ V + H+ + G+C+ ++T+ + +G L ++R + ++ + + Sbjct 763 DEAYVMASVDNPHVCRLLGICLTSTVQ-LITQLMPYGCLLDYVREHKDNIGSQYLLNWCV 821 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVE 774 Q+A ++YLE++ LVH ++ RN+L+ T +K++D G+ LGA +E E Sbjct 822 QIAKGMNYLEDRRLVHRDLAARNVLVK-------TPQHVKITDFGLAKLLGAEEKEYHAE 874 Query 775 R----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 I W+A E + + D W +G T+ E+ G P S+ ++ Sbjct 875 GGKVPIKWMALESIL--HRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASDISSILEKG 932 Query 831 HRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869 RLP+P + + +C + RP FR ++ + +++ Sbjct 933 ERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELILEFSKM 973 >sp|Q9I8X3|FGFR3_DANRE Fibroblast growth factor receptor 3 OS=Danio rerio OX=7955 GN=fgfr3 PE=2 SV=1 Length=800 Score = 155 bits (391), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 115/364 (32%), Positives = 172/364 (47%), Gaps = 40/364 (11%) Query 826 FYQRQHRLPEPSCPQLATL-TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884 + Q LP P +L+ + ++ E + T L + RL + + V+ Sbjct 387 WINTQKTLPAPPVQKLSKFPLKRQVSLESNSSMNSNTPLVRIARLSSSDGPMLPNVSELE 446 Query 885 PASDPT-VFHKRYLKKIRDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQH 940 SDP F + L + LGEG FG+V + D VAVK LK D + Sbjct 447 LPSDPKWEFTRTKLTLGKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKD 506 Query 941 RSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--------- 990 S E+++++ + H++II G C G L +++EY G+LR+YL Sbjct 507 LSDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLYVLVEYASKGNLREYLRARRPPGMD 564 Query 991 --------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 P ++ L+ A Q+ GM YL ++ IHRD AARNVL+ D ++KI DF Sbjct 565 YSFDTCKIPNETLTFKDLVSCAYQVARGMEYLASKKCIHRDPAARNVLVTEDNVMKIADF 624 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 GLA+ V +YY+ +G PV W APE L + + + SDVWS+GV L+E+ T Sbjct 625 GLARDV-HNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFT------ 677 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 L G + V L +LL+ G R+ +P C E+Y +M+ CW S RPTF Sbjct 678 --------LGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTF 729 Query 1163 ENLI 1166 L+ Sbjct 730 RQLV 733 Score = 64.3 bits (155), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 86/343 (25%), Positives = 146/343 (43%), Gaps = 54/343 (16%) Query 558 TSNLIIMRGARAS----PRTLNLSQLSFHRVDQKEITQLS-HLGQGTRTNVYEGRLRVEG 612 SN ++R AR S P N+S+L + E T+ LG+ + + E Sbjct 420 NSNTPLVRIARLSSSDGPMLPNVSELELPSDPKWEFTRTKLTLGKPLGEGCFGQVVMAEA 479 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHL 670 G +D E P P L V +K+L D + D++ E + H ++ Sbjct 480 IG------IDKEKPNKP-------LTVAVKMLKDDGTDKDLSDLVSEMEMMKMIGKHKNI 526 Query 671 AFVHGVCVR-GPENIMVTEYVEHGPLDVWLRRER----------GHVP---MAWKMVV-- 714 + G C + GP ++V EY G L +LR R +P + +K +V Sbjct 527 INLLGACTQDGPLYVLV-EYASKGNLREYLRARRPPGMDYSFDTCKIPNETLTFKDLVSC 585 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----RE 770 A Q+A + YL +K +H + RN+L+ + +K++D G+ + ++ Sbjct 586 AYQVARGMEYLASKKCIHRDPAARNVLVTEDNV-------MKIADFGLARDVHNIDYYKK 638 Query 771 ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 R+P W+APE L + + D W +G L EI G +P E + Sbjct 639 TTNGRLPVKWMAPEALFDRVYTHQS--DVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLK 696 Query 829 RQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 HR+ +P+ C +L + +C P+QRP+FR ++ D R+ Sbjct 697 EGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDRV 739 >sp|P43404|ZAP70_MOUSE Tyrosine-protein kinase ZAP-70 OS=Mus musculus OX=10090 GN=Zap70 PE=1 SV=3 Length=618 Score = 152 bits (385), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 123/377 (33%), Positives = 175/377 (46%), Gaps = 49/377 (13%) Query 799 GFGATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855 G L E+C + A +P+ H F Q Q R+ TL S T EP + Sbjct 245 GLIYRLKEVCPNSSASAAVAAPTLPAHPSTFTQPQRRV--------DTLNSDGYTPEPAR 296 Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP------TVFHKRYLKKIRD--LGEGH 907 S D R P + T +SP SDP +F KR + D LG G+ Sbjct 297 LASST----DKPRPMPMD-----TSVYESPYSDPEELKDKKLFLKRENLLVADIELGCGN 347 Query 908 FGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 FG V Y VA+K LK + +E I+ L + +I++ G C+ Sbjct 348 FGSVRQGVYRMRKKQID--VAIKVLKQGTEKADKDEMMREAQIMHQLDNPYIVRLIGVCQ 405 Query 968 DQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 + +L LVME G L +L + I ++ + Q+ GM YL ++++HRDLA Sbjct 406 AE---ALMLVMEMAGGGPLHKFLLGKKEEIPVSNVAELLHQVAMGMKYLEEKNFVHRDLA 462 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 ARNVLL N KI DFGL+KA+ YY R G P+ WYAPEC+ KF SDVW Sbjct 463 ARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVW 522 Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 S+GVT++E ++ Q P K M + + +++G+R+ P +CP E+Y Sbjct 523 SYGVTMWEAFSY---GQKPYKK-----------MKGPEVLDFIKQGKRMECPPECPPEMY 568 Query 1146 HLMKNCWETEASFRPTF 1162 LM +CW + RP F Sbjct 569 ALMSDCWIYKWEDRPDF 585 Score = 86.7 bits (213), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 67/242 (28%), Positives = 110/242 (45%), Gaps = 20/242 (8%) Query 631 RDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 R R +++ V +KVL A +M Q+ + ++ + GVC + ++V E Sbjct 357 RMRKKQIDVAIKVLKQGTEKADKDEMMREAQIMHQLDNPYIVRLIGVC-QAEALMLVMEM 415 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 GPL +L ++ +P++ + Q+A + YLE KN VH ++ RN+LL Sbjct 416 AGGGPLHKFLLGKKEEIPVSNVAELLHQVAMGMKYLEEKNFVHRDLAARNVLLV------ 469 Query 750 GTSPFIKLSDPGV--GLGA-----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 + K+SD G+ LGA +R + W APEC+ S+ D W +G Sbjct 470 -NRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECI--NFRKFSSRSDVWSYGV 526 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP-EPSC-PQLATLTSQCLTYEPTQRPSFR 860 T+ E G+ P + E F ++ R+ P C P++ L S C Y+ RP F Sbjct 527 TMWEAFSYGQKPYKKMKGPEVLDFIKQGKRMECPPECPPEMYALMSDCWIYKWEDRPDFL 586 Query 861 TI 862 T+ Sbjct 587 TV 588 >sp|G5EBZ8|ARK1_CAEEL Ack-related non-receptor tyrosine kinase OS=Caenorhabditis elegans OX=6239 GN=ark-1 PE=2 SV=1 Length=1043 Score = 155 bits (391), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 94/272 (35%), Positives = 144/272 (53%), Gaps = 21/272 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 ++LG+G FG V + + VAVK + +D S + QE I+ + HEH++ Sbjct 117 KELGQGEFGSVWQAGWKNSAGSDVIQVAVKCVGSDKLLATSSSFLQEAAIMTRMRHEHVV 176 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHA 1016 + G D K + LV E GSL + L R S + L +A+QI GM+YL Sbjct 177 RLYGVVLDT--KKIMLVSELATCGSLLECLHKPALRDSFPVHVLCDYAEQIAMGMSYLEL 234 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR--EDGDSPVFWYAPECLK 1074 Q IHRDLAARNVL+ + +LVKI DFGL++++ G +YYR + P+ W APEC+ Sbjct 235 QRLIHRDLAARNVLVFSPKLVKISDFGLSRSLGIGEDYYRSEFTPNLKLPIAWCAPECIN 294 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVW++GVT++E+ + + E+ + +L L + + E L Sbjct 295 FLKFTSKSDVWAYGVTIWEMFS-----------YGEMPWKGRSGAQILELVD--RKKELL 341 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 RP CP ++Y ++K W + RPTF +++ Sbjct 342 TRPKACPEDIYDMLKETWTHQVQDRPTFSDIV 373 Score = 75.9 bits (185), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 60/225 (27%), Positives = 110/225 (49%), Gaps = 25/225 (11%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE--RGHVPMAWK 711 +F + A++M+++ H H+ ++GV + + ++V+E G L L + R P+ Sbjct 159 SFLQEAAIMTRMRHEHVVRLYGVVLDTKKIMLVSELATCGSLLECLHKPALRDSFPVHVL 218 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV--GLGALSR 769 A+Q+A +SYLE + L+H ++ RN+L+ + +K+SD G+ LG Sbjct 219 CDYAEQIAMGMSYLELQRLIHRDLAARNVLVF-------SPKLVKISDFGLSRSLGIGED 271 Query 770 EERVERIP-------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 R E P W APEC+ ++ D W +G T+ E+ GE P + RS ++ Sbjct 272 YYRSEFTPNLKLPIAWCAPECI--NFLKFTSKSDVWAYGVTIWEMFSYGEMPWKGRSGAQ 329 Query 823 KEHFYQRQHRL---PEPSCPQ-LATLTSQCLTYEPTQRPSFRTIL 863 R+ L P+ +CP+ + + + T++ RP+F I+ Sbjct 330 ILELVDRKKELLTRPK-ACPEDIYDMLKETWTHQVQDRPTFSDIV 373 >sp|Q86PM4|FGFR_HYDVU Fibroblast growth factor receptor OS=Hydra vulgaris OX=6087 GN=FGFR PE=2 SV=1 Length=816 Score = 154 bits (388), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 104/282 (37%), Positives = 148/282 (52%), Gaps = 31/282 (11%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHII 960 LGEG FG+V D N + VAVK LK DC Q + EI++++++ H +I+ Sbjct 480 LGEGAFGRVFRATARDLPNHTGVQTVAVKMLKEDCCEQDLKDFISEIEVMKSIGKHINIL 539 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------------SIGLAQLLLFAQQIC 1008 QG+ L +V+EY G+LR +L + I L L F Q+ Sbjct 540 NLLAVSSQQGK--LYIVVEYCRHGNLRSFLKDNRPVMQANSVITKKITLYDLTSFCLQVA 597 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 GM +L ++ IHRD+AARNVL+ L+KI DFGLA+ + E +YYR DG PV W Sbjct 598 RGMNFLASKKCIHRDIAARNVLVGEGYLMKIADFGLARDIHE-QDYYRKCTDGRLPVKWM 656 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A E L + + SD+WSFG+ +E++T S GIA + +L +LL Sbjct 657 AIEALFDRVYTTQSDIWSFGILAWEIVTFGGSPYP---------GIA-----LEKLFDLL 702 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 ++G R+ RP C ++Y LM NCW+ S RPTF LI L+ Sbjct 703 KQGYRMERPLNCTDDMYTLMLNCWKEIPSKRPTFSQLIEDLE 744 Score = 58.5 bits (140), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 64/290 (22%), Positives = 116/290 (40%), Gaps = 35/290 (12%) Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 +P Q + V + D D+ E + S H ++ + V + + +V Sbjct 496 LPNHTGVQTVAVKMLKEDCCEQDLKDFISEIEVMKSIGKHINILNLLAVSSQQGKLYIVV 555 Query 688 EYVEHGPLDVWLRRER----GHVPMAWKMVVAQ------QLASALSYLENKNLVHGNVCG 737 EY HG L +L+ R + + K+ + Q+A +++L +K +H ++ Sbjct 556 EYCRHGNLRSFLKDNRPVMQANSVITKKITLYDLTSFCLQVARGMNFLASKKCIHRDIAA 615 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER--------IPWLAPECLPGGAN 789 RN+L+ G +K++D GL E+ R + W+A E L Sbjct 616 RNVLV-------GEGYLMKIAD--FGLARDIHEQDYYRKCTDGRLPVKWMAIEALFDRV- 665 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQ 847 +T D W FG EI G +P + + ++ +R+ P +C + TL Sbjct 666 -YTTQSDIWSFGILAWEIVTFGGSPYPGIALEKLFDLLKQGYRMERPLNCTDDMYTLMLN 724 Query 848 CLTYEPTQRPSFRTILRDLTRL----QPHNLADVLTVNPDSPASDPTVFH 893 C P++RP+F ++ DL R+ D+ + P+ S T H Sbjct 725 CWKEIPSKRPTFSQLIEDLERMLLDASSTEYIDLQPIQPERTESFSTSLH 774 >sp|P42686|SRK1_SPOLA Tyrosine-protein kinase isoform SRK1 OS=Spongilla lacustris OX=6055 GN=SRK1 PE=2 SV=1 Length=505 Score = 149 bits (377), Expect = 9e-37, Method: Compositional matrix adjust. Identities = 98/282 (35%), Positives = 144/282 (51%), Gaps = 27/282 (10%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 A++ K +K +R LG G FG+V ++ T VAVK LK G + Sbjct 229 ANEEWEIEKTQIKLLRRLGAGQFGEVWEGLWNGTTS-----VAVKTLKP--GTMSVEEFL 281 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLF 1003 QE I++ L H +I+ C E+ + +V E + GSL +YL + + QL+ Sbjct 282 QEASIMKRLRHPKLIQLYAVCTK--EEPIYIVTELMKYGSLLEYLRGEDGVLKIEQLVDV 339 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 A Q+ GM+YL Q+YIHRDLAARN+L+ + K+ DFGLA+ + E E Y Sbjct 340 AAQVASGMSYLEQQNYIHRDLAARNILVGEHGICKVADFGLARVIDE--EIYEAHTGAKF 397 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 P+ W APE +F SDVWSFGV LYE++T+ + P MT Sbjct 398 PIKWTAPEAAMYNRFTIKSDVWSFGVVLYEIITY---GRFPYPG-----------MTNPE 443 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + E +++ R+P P CP + + +M +CW + + RPTFE L Sbjct 444 VLEKIQQNYRMPCPANCPKQFHDIMLDCWREDPASRPTFETL 485 Score = 102 bits (254), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 73/233 (31%), Positives = 111/233 (48%), Gaps = 21/233 (9%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K L P + F + AS+M ++ H L ++ VC + +VTE +++G L + Sbjct 265 VAVKTLKPGTMSVE-EFLQEASIMKRLRHPKLIQLYAVCTKEEPIYIVTELMKYGSLLEY 323 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 LR E G + + + VA Q+AS +SYLE +N +H ++ RNIL+ G+ K++ Sbjct 324 LRGEDGVLKIEQLVDVAAQVASGMSYLEQQNYIHRDLAARNILVGEHGIC-------KVA 376 Query 759 DPGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 D GL + EE E I W APE N + D W FG L EI G Sbjct 377 D--FGLARVIDEEIYEAHTGAKFPIKWTAPEA--AMYNRFTIKSDVWSFGVVLYEIITYG 432 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862 P + E Q+ +R+P P+ CP Q + C +P RP+F T+ Sbjct 433 RFPYPGMTNPEVLEKIQQNYRMPCPANCPKQFHDIMLDCWREDPASRPTFETL 485 >sp|P0CY46|EGFR_APIME Epidermal growth factor receptor OS=Apis mellifera OX=7460 GN=Egfr PE=2 SV=1 Length=1292 Score = 155 bits (391), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 97/277 (35%), Positives = 141/277 (51%), Gaps = 20/277 (7%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 + + ++K LG G FG V + P + VA+K L G + E I Sbjct 705 IIKEEEMRKGGILGYGAFGNVYKGVWVPEGENVKIPVAIKVLHDGTGANTSKEFLDEAYI 764 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQIC 1008 + ++ H ++++ C + LV + +PLG L D++ R IG LL + QI Sbjct 765 MASVEHPNLLQLLAVCM---TSQMMLVTQLMPLGCLLDFVRRFKDKIGSKALLNWCTQIA 821 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 GMAYL + +HRDLAARNVL+ VKI DFGLAK + E Y+ G P+ W Sbjct 822 RGMAYLEERRLVHRDLAARNVLVQTPNCVKITDFGLAKLLDINEEQYKA-AGGKMPIKWL 880 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A EC++ F + SDVW+FGVT++E+LT+ G + + ELL Sbjct 881 ALECIQHRVFTHKSDVWAFGVTIWEVLTY--------------GGRPYENVPARNVPELL 926 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 E+GERLP+P C +VY +M CW +A RP+F+ L Sbjct 927 EKGERLPQPAICTIDVYMIMIKCWMLDAESRPSFKEL 963 Score = 84.0 bits (206), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 83/348 (24%), Positives = 152/348 (44%), Gaps = 42/348 (12%) Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 NL++L + ++E+ + LG G NVY+G EG E+ +P Sbjct 699 NLAKLRI--IKEEEMRKGGILGYGAFGNVYKGVWVPEG-----------ENVKIP----- 740 Query 635 QELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 V +KVL D + + + F + A +M+ V H +L + VC+ + ++VT+ + G Sbjct 741 ----VAIKVLHDGTGANTSKEFLDEAYIMASVEHPNLLQLLAVCMTS-QMMLVTQLMPLG 795 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L ++RR + + + Q+A ++YLE + LVH ++ RN+L+ T Sbjct 796 CLLDFVRRFKDKIGSKALLNWCTQIARGMAYLEERRLVHRDLAARNVLVQ-------TPN 848 Query 754 FIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K++D G+ EE+ + I WLA EC+ + D W FG T+ E+ Sbjct 849 CVKITDFGLAKLLDINEEQYKAAGGKMPIKWLALECI--QHRVFTHKSDVWAFGVTIWEV 906 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRD 865 G P ++ ++ RLP+P+ + + +C + RPSF+ + D Sbjct 907 LTYGGRPYENVPARNVPELLEKGERLPQPAICTIDVYMIMIKCWMLDAESRPSFKELAED 966 Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 ++ + L + D P+ + + IR+L G +L Sbjct 967 FAKMS-RDPGRYLAIKGDKYMRLPSYTLQDEKEMIRNLASAMDGPEAL 1013 >sp|P17713|STK_HYDVU Tyrosine-protein kinase STK OS=Hydra vulgaris OX=6087 GN=STK PE=2 SV=1 Length=509 Score = 149 bits (376), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 95/288 (33%), Positives = 146/288 (51%), Gaps = 28/288 (10%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 A D + L+ R LG G FG+V ++ T VAVK LK G + + Sbjct 229 AKDAWEIPRESLRLNRKLGAGQFGEVWAGVWNNTT-----QVAVKTLKP--GTMSPASFL 281 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLL 1002 E +++ L H+H+++ C D+ + + +V EY+ GSL DYL + ++ L L+ Sbjct 282 DEAGVMKKLRHKHLVQLYAICSDR--EPIYIVTEYMSGGSLLDYLSKGEGVNLQLPTLID 339 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 A Q+ GMA+L AQ YIHRDLAARN+L+ + + K+ DFGLA+ + + + Y E Sbjct 340 MAAQVASGMAFLEAQGYIHRDLAARNILVGENYICKVADFGLARLIED--DEYTAHEGAK 397 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 P+ W APE +F SDVWSFG+ + E++T I MT Sbjct 398 FPIKWTAPEAALYNRFTIKSDVWSFGILMAEIVTKGR--------------IPYPGMTNA 443 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + +E+G R+P CP +Y++M W + RPTF+ L +L+ Sbjct 444 QTIAEVEKGYRMPIMPGCPEPLYNIMLQTWNKDPENRPTFDYLQGVLE 491 Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 62/232 (27%), Positives = 108/232 (47%), Gaps = 22/232 (9%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P A +F + A +M ++ H HL ++ +C +VTEY+ G L Sbjct 264 QVAVKTLKPGTMSPA-SFLDEAGVMKKLRHKHLVQLYAICSDREPIYIVTEYMSGGSLLD 322 Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L + G ++ + + +A Q+AS +++LE + +H ++ RNIL+ G + K Sbjct 323 YLSKGEGVNLQLPTLIDMAAQVASGMAFLEAQGYIHRDLAARNILV-------GENYICK 375 Query 757 LSDPGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 ++D GL L ++ I W APE N + D W FG + EI Sbjct 376 VAD--FGLARLIEDDEYTAHEGAKFPIKWTAPEA--ALYNRFTIKSDVWSFGILMAEIVT 431 Query 810 DGEAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859 G P + ++ ++ +R+P P CP+ L + Q +P RP+F Sbjct 432 KGRIPYPGMTNAQTIAEVEKGYRMPIMPGCPEPLYNIMLQTWNKDPENRPTF 483 >sp|Q9H3Y6|SRMS_HUMAN Tyrosine-protein kinase Srms OS=Homo sapiens OX=9606 GN=SRMS PE=1 SV=1 Length=488 Score = 148 bits (374), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 102/277 (37%), Positives = 142/277 (51%), Gaps = 30/277 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 R LGEG+FG+V + G + VA+K +K+ + +EI L+ L HE + Sbjct 234 RKLGEGYFGEVWEGLW------LGSLPVAIKVIKS--ANMKLTDLAKEIQTLKGLRHERL 285 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHA 1016 I+ C G + + +V E + G+L+ +L ++ L LL FA Q+ EGM+YL Sbjct 286 IRLHAVC--SGGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLGFACQVAEGMSYLEE 343 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 Q +HRDLAARNVL+D+ K+ DFGLA+ + + + Y PV W APE Sbjct 344 QRVVHRDLAARNVLVDDGLACKVADFGLARLLKD--DIYSPSSSSKIPVKWTAPEAANYR 401 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 F SDVWSFGV L+E+ T+ Q P +G MT + + RG RLPR Sbjct 402 VFSQKSDVWSFGVLLHEVFTY---GQCP----------YEG-MTNHETLQQIMRGYRLPR 447 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 P CP EVY LM CW + RP+F L L +H Sbjct 448 PAACPAEVYVLMLECWRSSPEERPSFATLREKLHAIH 484 Score = 79.3 bits (194), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 71/240 (30%), Positives = 110/240 (46%), Gaps = 22/240 (9%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 L V +KV+ ++ + E +L + H L +H VC G +VTE + G L Sbjct 253 LPVAIKVIKSANMKLTDLAKEIQTLKG-LRHERLIRLHAVCSGGEPVYIVTELMRKGNLQ 311 Query 697 VWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +L G + + + A Q+A +SYLE + +VH ++ RN+L+ GLA Sbjct 312 AFLGTPEGRALRLPPLLGFACQVAEGMSYLEEQRVVHRDLAARNVLVDD-GLA------C 364 Query 756 KLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 K++D GL L +++ +IP W APE S D W FG L E+ Sbjct 365 KVAD--FGLARLLKDDIYSPSSSSKIPVKWTAPEA--ANYRVFSQKSDVWSFGVLLHEVF 420 Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDL 866 G+ P + + E R +RLP P +CP ++ L +C P +RPSF T+ L Sbjct 421 TYGQCPYEGMTNHETLQQIMRGYRLPRPAACPAEVYVLMLECWRSSPEERPSFATLREKL 480 >sp|Q91743|FGFR4_XENLA Fibroblast growth factor receptor 4 OS=Xenopus laevis OX=8355 GN=fgfr4 PE=2 SV=1 Length=828 Score = 152 bits (383), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 103/300 (34%), Positives = 151/300 (50%), Gaps = 41/300 (14%) Query 901 RDLGEGHFGKVSL---YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956 + LGEG FG+V Y + VAVK LK + + S E+++++ + H Sbjct 494 KPLGEGCFGQVVRAEGYGIEKDRPEKPVTVAVKMLKDNGTDKDLSDLISEMELMKVIGKH 553 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQ 999 ++II G C +G L +++EY G+LR++L P + Sbjct 554 KNIINLLGVCTQEG--PLFVIVEYASKGNLREFLRARRPPTPEDAFDITKVPEELLSFKD 611 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ V + +YY+ Sbjct 612 LVSCAYQVARGMEYLESKRCIHRDLAARNVLVAEDNVMKIADFGLARGVHD-IDYYKKTS 670 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 +G PV W APE L + + + SD+WSFGV +E+ T S P + EL Sbjct 671 NGRLPVKWMAPEALFDRVYTHQSDIWSFGVLTWEIFT-LGGSPYPVIPYEELF------- 722 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF---ENLIPILKTVHEKY 1176 +LL G R+ +P C E+Y LM+ CW + RPTF E+L IL V E+Y Sbjct 723 ------KLLREGHRMDKPSNCTHELYMLMRECWHAVPTQRPTFKQLEHLDRILTAVSEEY 776 Score = 70.5 bits (171), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 69/258 (27%), Positives = 117/258 (45%), Gaps = 35/258 (14%) Query 631 RDRGQE-LRVVLKVLDPSHHDIALA-FYETASLMSQV-SHTHLAFVHGVCVRGPENIMVT 687 +DR ++ + V +K+L + D L+ LM + H ++ + GVC + ++ Sbjct 514 KDRPEKPVTVAVKMLKDNGTDKDLSDLISEMELMKVIGKHKNIINLLGVCTQEGPLFVIV 573 Query 688 EYVEHGPLDVWLRRERGHVP-------------MAWKMVV--AQQLASALSYLENKNLVH 732 EY G L +LR R P +++K +V A Q+A + YLE+K +H Sbjct 574 EYASKGNLREFLRARRPPTPEDAFDITKVPEELLSFKDLVSCAYQVARGMEYLESKRCIH 633 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPG 786 ++ RN+L+A + +K++D G+ G ++ R+P W+APE L Sbjct 634 RDLAARNVLVAEDNV-------MKIADFGLARGVHDIDYYKKTSNGRLPVKWMAPEALFD 686 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATL 844 + + D W FG EI G +P E + HR+ +PS C +L L Sbjct 687 RVYTHQS--DIWSFGVLTWEIFTLGGSPYPVIPYEELFKLLREGHRMDKPSNCTHELYML 744 Query 845 TSQCLTYEPTQRPSFRTI 862 +C PTQRP+F+ + Sbjct 745 MRECWHAVPTQRPTFKQL 762 >sp|Q62371|DDR2_MOUSE Discoidin domain-containing receptor 2 OS=Mus musculus OX=10090 GN=Ddr2 PE=1 SV=2 Length=854 Score = 152 bits (383), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 99/299 (33%), Positives = 148/299 (49%), Gaps = 37/299 (12%) Query 892 FHKRYLKKIRDLGEGHFGKVSL-------------YCYDPTNDGTGEMVAVKALKADCGP 938 F ++ L LGEG FG+V L + D + + +VAVK L+AD Sbjct 558 FPRKLLAFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN-QPVLVAVKMLRADANK 616 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----- 993 R+ + +EI I+ L +II+ C E L ++ EY+ G L +L RH Sbjct 617 NARNDFLKEIKIMSRLKDPNIIRLLAVC--ITEDPLCMITEYMENGDLNQFLSRHEPLSS 674 Query 994 -----SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 ++ A L A QI GM YL + +++HRDLA RN L+ + +KI DFG+++ + Sbjct 675 CSSDATVSYANLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNL 734 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 G +YYR++ P+ W + E + KF ASDVW+FGVTL+E T C Q P Sbjct 735 YSG-DYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC---QEQPYSQ 790 Query 1109 LELIGIAQGQMTVLRLTELLERGER--LPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L + + R ++G + LP+P CP VY LM +CW E RP+F+ + Sbjct 791 LSDEQVIENTGEFFR-----DQGRQIYLPQPALCPDSVYKLMLSCWRRETKHRPSFQEI 844 Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 73/254 (29%), Positives = 113/254 (44%), Gaps = 34/254 (13%) Query 634 GQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 Q + V +K+L + A F + +MS++ ++ + VC+ M+TEY+E+ Sbjct 600 NQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIRLLAVCITEDPLCMITEYMEN 659 Query 693 GPLDVWLRRER--------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 G L+ +L R V A +A Q+AS + YL + N VH ++ RN L+ Sbjct 660 GDLNQFLSRHEPLSSCSSDATVSYANLKFMATQIASGMKYLSSLNFVHRDLATRNCLV-- 717 Query 745 LGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKW 798 G + IK++D G+ S + V I W++ E + G +TA D W Sbjct 718 -----GKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLG--KFTTASDVW 770 Query 799 GFGATLLE-ICFDGEAPLQSRSPSE----KEHFYQRQHR---LPEPS-CPQ-LATLTSQC 848 FG TL E F E P S + F++ Q R LP+P+ CP + L C Sbjct 771 AFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQIYLPQPALCPDSVYKLMLSC 830 Query 849 LTYEPTQRPSFRTI 862 E RPSF+ I Sbjct 831 WRRETKHRPSFQEI 844 >sp|Q62190|RON_MOUSE Macrophage-stimulating protein receptor OS=Mus musculus OX=10090 GN=Mst1r PE=1 SV=3 Length=1378 Score = 153 bits (386), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 112/327 (34%), Positives = 168/327 (51%), Gaps = 37/327 (11%) Query 854 TQRPSFRT---ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910 T P RT L+DL R+ + DVL + + V H + +G+GHFG Sbjct 1024 TSVPLLRTESIRLQDLDRMLLAEVKDVLIPH------EQVVIHTDQV-----IGKGHFGV 1072 Query 911 VSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 V Y + T+ + A+K+L Q + +E ++R L+H +I+ G Sbjct 1073 V--YHGEYTDGAQNQTHCAIKSLSRITEVQEVEAFLREGLLMRGLHHPNILALIGIMLPP 1130 Query 970 GEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027 E ++++ Y+ G L ++ P+ + + L+ F Q+ GM YL Q ++HRDLAAR Sbjct 1131 -EGLPRVLLPYMRHGDLLHFIRSPQRNPTVKDLVSFGLQVACGMEYLAEQKFVHRDLAAR 1189 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS--PVFWYAPECLKEYKFYYASDVW 1085 N +LD VK+ DFGLA+ V + EYY VR+ + PV W A E L+ Y+F SDVW Sbjct 1190 NCMLDESFTVKVADFGLARGVLD-KEYYSVRQHRHARLPVKWMALESLQTYRFTTKSDVW 1248 Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 SFGV L+ELLT +PP ++ L+ L +G RLP+P+ CP +Y Sbjct 1249 SFGVLLWELLTR----GAPPYPHID----------PFDLSHFLAQGRRLPQPEYCPDSLY 1294 Query 1146 HLMKNCWETEASFRPTFENLIPILKTV 1172 H+M CWE + + RPTF L+ +K V Sbjct 1295 HVMLRCWEADPAARPTFRALVLEVKQV 1321 Score = 75.1 bits (183), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 63/235 (27%), Positives = 107/235 (46%), Gaps = 22/235 (9%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENI--MVTEYVEHGPLDVWLRRERGHVPMAWK 711 AF LM + H ++ + G+ + PE + ++ Y+ HG L ++R + + + Sbjct 1104 AFLREGLLMRGLHHPNILALIGIMLP-PEGLPRVLLPYMRHGDLLHFIRSPQRNPTVKDL 1162 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--- 768 + Q+A + YL + VH ++ RN +L S +K++D G+ G L Sbjct 1163 VSFGLQVACGMEYLAEQKFVHRDLAARNCMLDE-------SFTVKVADFGLARGVLDKEY 1215 Query 769 ---REERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 R+ R R+P W+A E L +T D W FG L E+ G P P + Sbjct 1216 YSVRQHRHARLPVKWMALESL--QTYRFTTKSDVWSFGVLLWELLTRGAPPYPHIDPFDL 1273 Query 824 EHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 HF + RLP+P CP L + +C +P RP+FR ++ ++ ++ L D Sbjct 1274 SHFLAQGRRLPQPEYCPDSLYHVMLRCWEADPAARPTFRALVLEVKQVVASLLGD 1328 >sp|Q62270|SRMS_MOUSE Tyrosine-protein kinase Srms OS=Mus musculus OX=10090 GN=Srms PE=2 SV=2 Length=496 Score = 147 bits (370), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 104/278 (37%), Positives = 145/278 (52%), Gaps = 28/278 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LGEG FG+V ++ G+ VAVK +K+ + +EI+ L++L HE +I Sbjct 238 RKLGEGFFGEV----WEGLWLGSIP-VAVKVIKS--ADMKLADLTKEIEALKSLRHERLI 290 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQ 1017 + C GE + +V E + G+L+ YL ++ L LL FA Q+ EGM+YL + Sbjct 291 RLHAIC-SLGE-PVYIVTELMGKGNLQVYLGSSEGKALSLPHLLGFACQVAEGMSYLEER 348 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDLAARNVL+ +D K+ DFGLA+ + + + Y PV W APE Sbjct 349 RVVHRDLAARNVLVGDDLTCKVADFGLARLLKD--DVYSPSSGSKIPVKWTAPEAANYRV 406 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFG+ LYE+ T+ Q P +G MT + + RG RLPRP Sbjct 407 FSQKSDVWSFGILLYEVFTY---GQCP----------YEG-MTNHETLQQISRGYRLPRP 452 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 CP EVY LM CW+ RPTF L L ++ + Sbjct 453 AVCPAEVYVLMVECWKGSPEERPTFAILREKLNAINRR 490 Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 70/237 (30%), Positives = 110/237 (46%), Gaps = 23/237 (10%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +KV+ + +A E +L S + H L +H +C G +VTE + G L V+ Sbjct 259 VAVKVIKSADMKLADLTKEIEALKS-LRHERLIRLHAICSLGEPVYIVTELMGKGNLQVY 317 Query 699 LRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 L G + + + A Q+A +SYLE + +VH ++ RN+L+ G K+ Sbjct 318 LGSSEGKALSLPHLLGFACQVAEGMSYLEERRVVHRDLAARNVLV-------GDDLTCKV 370 Query 758 SDPGVGLGALSREERVE-----RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +D GL L +++ +IP W APE S D W FG L E+ Sbjct 371 AD--FGLARLLKDDVYSPSSGSKIPVKWTAPEA--ANYRVFSQKSDVWSFGILLYEVFTY 426 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRD 865 G+ P + + E R +RLP P+ CP ++ L +C P +RP+F ILR+ Sbjct 427 GQCPYEGMTNHETLQQISRGYRLPRPAVCPAEVYVLMVECWKGSPEERPTF-AILRE 482 >sp|Q03145|EPHA2_MOUSE Ephrin type-A receptor 2 OS=Mus musculus OX=10090 GN=Epha2 PE=1 SV=3 Length=977 Score = 151 bits (382), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 87/282 (31%), Positives = 143/282 (51%), Gaps = 18/282 (6%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 T H + + + +G G FG+V ++ VA+K LKA + R + E Sbjct 607 TEIHPSCVARQKVIGAGEFGEVYKGTLKASSGKKEIPVAIKTLKAGYTEKQRVDFLSEAS 666 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQI 1007 I+ H +II+ +G K + ++ EY+ G+L +L + QL+ + I Sbjct 667 IMGQFSHHNIIRLEGVVSKY--KPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGI 724 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 GM YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W Sbjct 725 ASGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRW 784 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + KF ASDVWS+G+ ++E++T+ + + EL + + + Sbjct 785 TAPEAISYRKFTSASDVWSYGIVMWEVMTYGER------PYWEL--------SNHEVMKA 830 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + G RLP P CP +Y LM CW+ E S RP F +++ IL Sbjct 831 INDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVSIL 872 Score = 95.9 bits (237), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 75/260 (29%), Positives = 121/260 (47%), Gaps = 21/260 (8%) Query 635 QELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +E+ V +K L + + + F AS+M Q SH ++ + GV + +++TEY+E+G Sbjct 640 KEIPVAIKTLKAGYTEKQRVDFLSEASIMGQFSHHNIIRLEGVVSKYKPMMIITEYMENG 699 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 LD +LR + G + + + + +AS + YL N N VH ++ RNIL+ ++ Sbjct 700 ALDKFLREKDGEFSVLQLVGMLRGIASGMKYLANMNYVHRDLAARNILV-------NSNL 752 Query 754 FIKLSDPGVGLGALSREERVE-----RIP--WLAPECLPGGANSLSTAMDKWGFGATLLE 806 K+SD G+ E +IP W APE + ++A D W +G + E Sbjct 753 VCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAI--SYRKFTSASDVWSYGIVMWE 810 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILR 864 + GE P S E RLP P CP + L QC E ++RP F I+ Sbjct 811 VMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVS 870 Query 865 DLTRL--QPHNLADVLTVNP 882 L +L P +L + +P Sbjct 871 ILDKLIRAPDSLKTLADFDP 890 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens OX=9606 GN=EPHA2 PE=1 SV=2 Length=976 Score = 151 bits (381), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 90/283 (32%), Positives = 146/283 (52%), Gaps = 20/283 (7%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEI 948 T H + + + +G G FG+V T+ G E+ VA+K LKA + R + E Sbjct 606 TEIHPSCVTRQKVIGAGEFGEVYKGMLK-TSSGKKEVPVAIKTLKAGYTEKQRVDFLGEA 664 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006 I+ H +II+ +G K + ++ EY+ G+L +L + QL+ + Sbjct 665 GIMGQFSHHNIIRLEGVISKY--KPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRG 722 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ Sbjct 723 IAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIR 782 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE + KF ASDVWSFG+ ++E++T+ + + EL + + + Sbjct 783 WTAPEAISYRKFTSASDVWSFGIVMWEVMTYGER------PYWEL--------SNHEVMK 828 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + G RLP P CP +Y LM CW+ E + RP F +++ IL Sbjct 829 AINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSIL 871 Score = 93.6 bits (231), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 83/306 (27%), Positives = 133/306 (43%), Gaps = 41/306 (13%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 +T+ +G G VY+G L+ GK +E+ V +K L + Sbjct 613 VTRQKVIGAGEFGEVYKGMLKTSS------GK--------------KEVPVAIKTLKAGY 652 Query 649 HDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 + + F A +M Q SH ++ + GV + +++TEY+E+G LD +LR + G Sbjct 653 TEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFS 712 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 + + + + +A+ + YL N N VH ++ RNIL+ ++ K+SD G+ Sbjct 713 VLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILV-------NSNLVCKVSDFGLSRVLE 765 Query 768 SREERVE-----RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 E +IP W APE + ++A D W FG + E+ GE P S Sbjct 766 DDPEATYTTSGGKIPIRWTAPEAI--SYRKFTSASDVWSFGIVMWEVMTYGERPYWELSN 823 Query 821 SEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLAD 876 E RLP P CP + L QC E +RP F I+ L +L P +L Sbjct 824 HEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKT 883 Query 877 VLTVNP 882 + +P Sbjct 884 LADFDP 889 >sp|P35546|RET_MOUSE Proto-oncogene tyrosine-protein kinase receptor Ret OS=Mus musculus OX=10090 GN=Ret PE=1 SV=2 Length=1115 Score = 151 bits (382), Expect = 9e-36, Method: Compositional matrix adjust. Identities = 104/310 (34%), Positives = 143/310 (46%), Gaps = 43/310 (14%) Query 892 FHKRYLKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 F ++ L + LGEG FGKV + VAVK LK + E ++ Sbjct 720 FPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNL 779 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------------------- 990 L+ + H H+IK G C G L L++EY GSLR +L Sbjct 780 LKQVNHPHVIKLYGACSQDG--PLLLIVEYAKYGSLRGFLRDSRKIGPAYVSGGGSRNSS 837 Query 991 -----PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 + + L+ FA QI GM YL +HRDLAARN+L+ R +KI DFGL+ Sbjct 838 SLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLS 897 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + V E Y + + G PV W A E L ++ + SDVWSFGV L+E++T Sbjct 898 RDVYEEDSYVK-KSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVT--------- 947 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L G + RL LL+ G R+ RPD C E+Y LM CW+ E RP F ++ Sbjct 948 -----LGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 1002 Query 1166 IPILKTVHEK 1175 L+ + K Sbjct 1003 SKDLEKMMVK 1012 Score = 79.3 bits (194), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 67/241 (28%), Positives = 105/241 (44%), Gaps = 40/241 (17%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------------ 707 +L+ QV+H H+ ++G C + +++ EY ++G L +LR R P Sbjct 778 NLLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIGPAYVSGGGSRNSS 837 Query 708 -----------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 M + A Q++ + YL LVH ++ RNIL +AEG +K Sbjct 838 SLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNIL-----VAEGRK--MK 890 Query 757 LSDPGVGLGALSREERVE----RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +SD G+ + V+ RIP W+A E L + +T D W FG L EI Sbjct 891 ISDFGLSRDVYEEDSYVKKSKGRIPVKWMAIESL--FDHIYTTQSDVWSFGVLLWEIVTL 948 Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 G P P + + HR+ P+ ++ L QC EP +RP F I +DL + Sbjct 949 GGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEK 1008 Query 869 L 869 + Sbjct 1009 M 1009 >sp|G3V9H8|RET_RAT Proto-oncogene tyrosine-protein kinase receptor Ret OS=Rattus norvegicus OX=10116 GN=Ret PE=1 SV=1 Length=1115 Score = 151 bits (382), Expect = 9e-36, Method: Compositional matrix adjust. Identities = 104/310 (34%), Positives = 143/310 (46%), Gaps = 43/310 (14%) Query 892 FHKRYLKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 F ++ L + LGEG FGKV + VAVK LK + E ++ Sbjct 720 FPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNL 779 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------------------- 990 L+ + H H+IK G C G L L++EY GSLR +L Sbjct 780 LKQVNHPHVIKLYGACSQDG--PLLLIVEYAKYGSLRGFLRDSRKIGPAYVSSGGSRNSS 837 Query 991 -----PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 + + L+ FA QI GM YL +HRDLAARN+L+ R +KI DFGL+ Sbjct 838 SLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLS 897 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + V E Y + + G PV W A E L ++ + SDVWSFGV L+E++T Sbjct 898 RDVYEEDSYVK-KSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVT--------- 947 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L G + RL LL+ G R+ RPD C E+Y LM CW+ E RP F ++ Sbjct 948 -----LGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 1002 Query 1166 IPILKTVHEK 1175 L+ + K Sbjct 1003 SKDLEKMMVK 1012 Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 67/241 (28%), Positives = 105/241 (44%), Gaps = 40/241 (17%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------------ 707 +L+ QV+H H+ ++G C + +++ EY ++G L +LR R P Sbjct 778 NLLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIGPAYVSSGGSRNSS 837 Query 708 -----------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 M + A Q++ + YL LVH ++ RNIL +AEG +K Sbjct 838 SLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNIL-----VAEGRK--MK 890 Query 757 LSDPGVGLGALSREERVE----RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +SD G+ + V+ RIP W+A E L + +T D W FG L EI Sbjct 891 ISDFGLSRDVYEEDSYVKKSKGRIPVKWMAIESL--FDHIYTTQSDVWSFGVLLWEIVTL 948 Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 G P P + + HR+ P+ ++ L QC EP +RP F I +DL + Sbjct 949 GGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEK 1008 Query 869 L 869 + Sbjct 1009 M 1009 >sp|P13406|FYN_XENLA Tyrosine-protein kinase Fyn OS=Xenopus laevis OX=8355 GN=fyn PE=2 SV=3 Length=537 Score = 147 bits (370), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 92/277 (33%), Positives = 139/277 (50%), Gaps = 29/277 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ I+ LG G FG+V + ++ VA+K LK G + +E I++ L H Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAIKTLKP--GTMSPESFLEEAQIMKKLKH 323 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013 + +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVARGMAY 380 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + +YIHRDL + N+L+ N + KI DFGLA+ + + Y R+ P+ W APE Sbjct 381 IERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +F SDVWSFG+ L EL+T + M + E +ERG R Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +P P CP ++ LM NCW+ + RPTFE L L+ Sbjct 485 MPCPQDCPISLHELMLNCWKKDPEERPTFEYLQGFLE 521 Score = 76.6 bits (187), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 65/230 (28%), Positives = 101/230 (44%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L Sbjct 295 KVAIKTLKPGTMSPE-SFLEEAQIMKKLKHDKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 352 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G +V +A Q+A ++Y+E N +H ++ NIL+ G K Sbjct 353 FLKDGEGRALKLPNLVDMAAQVARGMAYIERMNYIHRDLRSANILV-------GNGLICK 405 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 P + E +R +R+P P CP L L C +P +RP+F Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMLNCWKKDPEERPTF 513 >sp|P00527|YES_AVISY Tyrosine-protein kinase transforming protein Yes (Fragment) OS=Y73 avian sarcoma virus OX=11884 GN=V-YES PE=3 SV=2 Length=528 Score = 146 bits (369), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 101/305 (33%), Positives = 150/305 (49%), Gaps = 32/305 (10%) Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 H L V TV P + A D + L+ LG+G FG+V + ++ T VA Sbjct 239 HKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK-----VA 293 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK G + QE I++ L H+ ++ E+ + +V E++ GSL D Sbjct 294 IKTLK--LGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVS---EEPIYIVTEFMTKGSLLD 348 Query 989 YLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ ++ + KI DFGLA Sbjct 349 FLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLA 408 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 409 RLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR------ 460 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + M + E +ERG R+P P CP ++ LMK CW+ + RPTFE + Sbjct 461 --------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYI 512 Query 1166 IPILK 1170 L+ Sbjct 513 QSFLE 517 Score = 73.6 bits (179), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 61/217 (28%), Positives = 98/217 (45%), Gaps = 18/217 (8%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 AF + A +M ++ H L ++ V P I VTE++ G L +L+ G ++V Sbjct 306 AFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEFMTKGSLLDFLKEGEGKFLKLPQLV 364 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 +A Q+A ++Y+E N +H ++ NIL+ G + K++D G+ E Sbjct 365 DMAAQIADGMAYIERMNYIHRDLRAANILV-------GDNLVCKIADFGLARLIEDNEYT 417 Query 773 VER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 + I W APE G ++ + D W FG L E+ G P E Sbjct 418 ARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKGRVPYPGMVNREVLEQV 475 Query 828 QRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 +R +R+P P CP+ L L C +P +RP+F I Sbjct 476 ERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYI 512 >sp|P10447|ABL_FSVHY Tyrosine-protein kinase transforming protein Abl OS=Feline sarcoma virus (strain Hardy-Zuckerman 2) OX=11776 GN=ABL PE=2 SV=1 Length=439 Score = 144 bits (364), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 98/290 (34%), Positives = 142/290 (49%), Gaps = 27/290 (9%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 TV SP D + + LG G +G+V Y+ VAVK LK D Sbjct 173 TVYGVSPNYDKWEMERTDITMKHKLGGGQYGEV----YEGVWKKYSLTVAVKTLKEDT-- 226 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSI 995 + +E +++ + H ++++ G C E ++ E++ G+L DYL R + Sbjct 227 MEVEEFLKEAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLDYLRECNRQEV 284 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 LL A QI M YL +++IHRDLAARN L+ + LVK+ DFGL++ + + Y Sbjct 285 NAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT--GDTY 342 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 P+ W APE L KF SDVW+FGV L+E+ T+ SP GI Sbjct 343 TAHAGTKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATY---GMSP------YPGID 393 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 Q + ELLE+ R+ RP+ CP +VY LM+ CW+ S RP F + Sbjct 394 LSQ-----VYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPAFAEI 438 Score = 99.8 bits (247), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 78/287 (27%), Positives = 125/287 (44%), Gaps = 42/287 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 +++ +IT LG G VYEG + L V +K Sbjct 186 MERTDITMKHKLGGGQYGEVYEGVWK------------------------KYSLTVAVKT 221 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702 L ++ F + A++M ++ H +L + GVC R P ++TE++ +G L +LR Sbjct 222 LKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECN 280 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 R V + +A Q++SA+ YLE KN +H ++ RN L+ G + +K++D G+ Sbjct 281 RQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV-------GENHLVKVADFGL 333 Query 763 G---LGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 G + P W APE L N S D W FG L EI G +P Sbjct 334 SRLMTGDTYTAHAGTKFPIKWTAPESL--AYNKFSIKSDVWAFGVLLWEIATYGMSPYPG 391 Query 818 RSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTI 862 S+ ++ +R+ P CP+ + L C + P+ RP+F I Sbjct 392 IDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPAFAEI 438 >sp|Q1KL86|EPHA2_MACFA Ephrin type-A receptor 2 OS=Macaca fascicularis OX=9541 GN=EPHA2 PE=2 SV=1 Length=976 Score = 150 bits (379), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 87/283 (31%), Positives = 145/283 (51%), Gaps = 20/283 (7%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEI 948 T H + + + +G G FG+V T+ G E+ VA+K LKA + R + E Sbjct 606 TEIHPSCVTRQKVIGAGEFGEVYKGTLK-TSSGKKEVPVAIKTLKAGYTEKQRVDFLGEA 664 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQ 1006 I+ H +II+ +G K + ++ E++ G+L +L + QL+ + Sbjct 665 GIMGQFSHHNIIRLEGVISKY--KPMMIITEFMENGALDKFLREKDGEFSVLQLVGMLRG 722 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ Sbjct 723 IAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIR 782 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE + KF ASDVWSFG+ ++E++T+ + +++ + + Sbjct 783 WTAPEAISYRKFTSASDVWSFGIVMWEVMTYGER--------------PYWELSNHEVMK 828 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + G RLP P CP +Y LM CW+ E + RP F +++ IL Sbjct 829 AINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSIL 871 Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 82/306 (27%), Positives = 133/306 (43%), Gaps = 41/306 (13%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 +T+ +G G VY+G L+ GK +E+ V +K L + Sbjct 613 VTRQKVIGAGEFGEVYKGTLKTSS------GK--------------KEVPVAIKTLKAGY 652 Query 649 HDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 + + F A +M Q SH ++ + GV + +++TE++E+G LD +LR + G Sbjct 653 TEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEFMENGALDKFLREKDGEFS 712 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 + + + + +A+ + YL N N VH ++ RNIL+ ++ K+SD G+ Sbjct 713 VLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILV-------NSNLVCKVSDFGLSRVLE 765 Query 768 SREERVE-----RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 E +IP W APE + ++A D W FG + E+ GE P S Sbjct 766 DDPEATYTTSGGKIPIRWTAPEAI--SYRKFTSASDVWSFGIVMWEVMTYGERPYWELSN 823 Query 821 SEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLAD 876 E RLP P CP + L QC E +RP F I+ L +L P +L Sbjct 824 HEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKT 883 Query 877 VLTVNP 882 + +P Sbjct 884 LADFDP 889 >sp|Q09YN5|MET_RABIT Hepatocyte growth factor receptor OS=Oryctolagus cuniculus OX=9986 GN=MET PE=3 SV=1 Length=1382 Score = 150 bits (380), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 98/284 (35%), Positives = 146/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + T+ + G+ Sbjct 1305 QPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISTIFSTFIGE 1348 Score = 62.0 bits (149), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1295 VYLLQGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISTI 1341 >sp|O02466|ILPR_BRALA Insulin-like peptide receptor OS=Branchiostoma lanceolatum OX=7740 PE=2 SV=1 Length=1363 Score = 150 bits (380), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 108/327 (33%), Positives = 160/327 (49%), Gaps = 53/327 (16%) Query 879 TVNPDSPASDPTVFHKRY------LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKA 931 +VNP+ +SD + + IR+LG+G FG V D D VAVK Sbjct 970 SVNPEYMSSDDVYVPDEWEVPREKITLIRELGQGSFGMVYEGEAKDVVKDEPMVSVAVKT 1029 Query 932 LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP 991 + + R + E +++T H++K G +G+ +L +VME + LG L++YL Sbjct 1030 VNESASIRERIEFLNEASVMKTFNCHHVVKLMGVVS-KGQPTL-VVMELMALGDLKNYLR 1087 Query 992 RH----SIGLAQ-------------------------LLLFAQQICEGMAYLHAQHYIHR 1022 RH +GL+ ++ A I +GM+YL A+ ++HR Sbjct 1088 RHRPEEDVGLSDSPASNEAKNSPFAENDNDLPPTFKDIIQMAGVIADGMSYLAAKKFVHR 1147 Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082 DLA RN ++ DR VKIGDFG+ + + E +YYR G PV W +PE LK F S Sbjct 1148 DLACRNCMVAQDRTVKIGDFGMTRDIYET-DYYRKGGKGLLPVRWMSPESLKVGVFTSQS 1206 Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 DVWS+GV L+E+ T S P QG+ L +++ G L +P+ CP Sbjct 1207 DVWSYGVVLWEMATLA----SQP---------YQGKSNEEVLKFVIDGG-MLEKPEGCPN 1252 Query 1143 EVYHLMKNCWETEASFRPTFENLIPIL 1169 ++Y LMK CW+ S RPTF ++ IL Sbjct 1253 KLYDLMKLCWQYRQSMRPTFLEIVEIL 1279 Score = 73.2 bits (178), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 80/326 (25%), Positives = 133/326 (41%), Gaps = 65/326 (20%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +++IT + LGQG+ VYEG E + ++P+V V +K Sbjct 989 VPREKITLIRELGQGSFGMVYEG----------EAKDVVKDEPMV---------SVAVKT 1029 Query 644 LDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 ++ S + F AS+M + H+ + GV +G ++V E + G L +LRR Sbjct 1030 VNESASIRERIEFLNEASVMKTFNCHHVVKLMGVVSKGQPTLVVMELMALGDLKNYLRRH 1089 Query 703 R-------------------------GHVPMAWKMVV--AQQLASALSYLENKNLVHGNV 735 R +P +K ++ A +A +SYL K VH ++ Sbjct 1090 RPEEDVGLSDSPASNEAKNSPFAENDNDLPPTFKDIIQMAGVIADGMSYLAAKKFVHRDL 1149 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGAN 789 RN ++A+ +K+ D G+ + + + + W++PE L G Sbjct 1150 ACRNCMVAQ-------DRTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKVGV- 1201 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQ 847 ++ D W +G L E+ P Q +S E F L +P CP +L L Sbjct 1202 -FTSQSDVWSYGVVLWEMATLASQPYQGKSNEEVLKFVIDGGMLEKPEGCPNKLYDLMKL 1260 Query 848 CLTYEPTQRPSFRTILRDLT-RLQPH 872 C Y + RP+F I+ L+ LQ H Sbjct 1261 CWQYRQSMRPTFLEIVEILSPELQAH 1286 >sp|P16056|MET_MOUSE Hepatocyte growth factor receptor OS=Mus musculus OX=10090 GN=Met PE=1 SV=1 Length=1379 Score = 150 bits (380), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 147/284 (52%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L + S + E I++ H ++ Sbjct 1082 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNV 1137 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1138 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1196 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1197 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1255 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1256 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITIYLLQGRRLL 1301 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + ++ + G+ Sbjct 1302 QPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISSIFSTFIGE 1345 Score = 62.0 bits (149), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1122 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1180 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1181 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1233 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1234 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1291 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1292 IYLLQGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISSI 1338 >sp|P27446|FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiphophorus hellerii OX=8084 GN=fyn PE=2 SV=3 Length=537 Score = 146 bits (368), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 92/277 (33%), Positives = 140/277 (51%), Gaps = 29/277 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ I+ LG G FG+V + ++ T VAVK LK G + +E I++ L H Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGTTK-----VAVKTLKP--GTMSPESFLEEAQIMKKLRH 323 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013 + +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 380 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + +YIHRDL + N+L+ ++ + KI DFGLA+ + + Y R+ P+ W APE Sbjct 381 IERMNYIHRDLRSANILVGDNLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +F SDVWSFG+ L EL+T + M + E +ERG R Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +P P CP ++ LM CW+ + RPTFE L L+ Sbjct 485 MPCPQDCPASLHELMLQCWKKDPEERPTFEYLQAFLE 521 Score = 78.6 bits (192), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 66/230 (29%), Positives = 104/230 (45%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L Sbjct 295 KVAVKTLKPGTMSPE-SFLEEAQIMKKLRHDKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 352 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G + K Sbjct 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GDNLVCK 405 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 P + E +R +R+P P CP L L QC +P +RP+F Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPASLHELMLQCWKKDPEERPTF 513 >sp|Q9VZI2|ACK_DROME Activated Cdc42 kinase Ack OS=Drosophila melanogaster OX=7227 GN=Ack PE=1 SV=2 Length=1073 Score = 150 bits (378), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 97/287 (34%), Positives = 148/287 (52%), Gaps = 22/287 (8%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEI 948 + H++ + LG+G FG V + + G VAVK LK+D P + +E+ Sbjct 117 LIHEKDITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREV 176 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQ 1005 + L H ++++ G Q + ++ E GSL D L RH+ L + ++ Sbjct 177 QAMHALDHANLVRLYGVVLSQ---PMMMITELAERGSLLDTLRKQCRHT-SLTIIWNWSV 232 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 QI GMAYL + ++HRDLA RNVLL +KIGDFGL +A+P+ + Y + E P Sbjct 233 QIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPF 292 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 W APE L+ +F +ASD W FGVTL+E+ + + +G+ Q+ L Sbjct 293 PWCAPESLRFRQFSHASDTWMFGVTLWEMFSFGEDP---------WVGLNGSQI----LR 339 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 ++ GERL +PD CP +VY +M CW+ + RPTF L L ++ Sbjct 340 KIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYLASM 386 Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 72/245 (29%), Positives = 110/245 (45%), Gaps = 26/245 (11%) Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 VLK + + I F+ M + H +L ++GV + P +M+TE E G L L Sbjct 157 VLKSDNLTQPGIIDDFFREVQAMHALDHANLVRLYGVVLSQPM-MMITELAERGSLLDTL 215 Query 700 RRERGHVPMA--WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 R++ H + W V Q+ + ++YLE K +H ++ RN+LLA IK+ Sbjct 216 RKQCRHTSLTIIWNWSV--QIVTGMAYLEQKRFLHRDLACRNVLLA-------AGNKIKI 266 Query 758 SDPGVGLGALSREE--------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 D G+ + AL +E+ + PW APE L S A D W FG TL E+ Sbjct 267 GDFGL-MRALPQEDDCYVMSEHKKVPFPWCAPESL--RFRQFSHASDTWMFGVTLWEMFS 323 Query 810 DGEAPLQSRSPSEKEHFYQRQ-HRLPEPSC--PQLATLTSQCLTYEPTQRPSFRTILRDL 866 GE P + S+ R+ RL +P P + + QC P +RP+F + L Sbjct 324 FGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYL 383 Query 867 TRLQP 871 + P Sbjct 384 ASMSP 388 >sp|P09324|YES_CHICK Tyrosine-protein kinase Yes OS=Gallus gallus OX=9031 GN=YES1 PE=1 SV=3 Length=541 Score = 146 bits (368), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 101/305 (33%), Positives = 150/305 (49%), Gaps = 32/305 (10%) Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 H L V TV P + A D + L+ LG+G FG+V + ++ T VA Sbjct 247 HKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK-----VA 301 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK G + QE I++ L H+ ++ E+ + +V E++ GSL D Sbjct 302 IKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVVS---EEPIYIVTEFMTKGSLLD 356 Query 989 YLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ ++ + KI DFGLA Sbjct 357 FLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLA 416 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 417 RLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR------ 468 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + M + E +ERG R+P P CP ++ LMK CW+ + RPTFE + Sbjct 469 --------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYI 520 Query 1166 IPILK 1170 L+ Sbjct 521 QSFLE 525 Score = 76.6 bits (187), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 65/233 (28%), Positives = 105/233 (45%), Gaps = 19/233 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P + AF + A +M ++ H L ++ V P I VTE++ G L Sbjct 299 KVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEFMTKGSLLD 356 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G ++V +A Q+A ++Y+E N +H ++ NIL+ G + K Sbjct 357 FLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILV-------GDNLVCK 409 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 410 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 467 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 P E +R +R+P P CP+ L L C +P +RP+F I Sbjct 468 RVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYI 520 >sp|P29321|EPHA8_RAT Ephrin type-A receptor 8 (Fragment) OS=Rattus norvegicus OX=10116 GN=Epha8 PE=2 SV=1 Length=372 Score = 142 bits (358), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 89/264 (34%), Positives = 136/264 (52%), Gaps = 19/264 (7%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VA+KALKA + R + +E I+ H +II+ +G +G ++ +V EY+ GSL Sbjct 31 VAIKALKAGYTERQRQDFLREAAIMGQFDHPNIIRLEGVVT-RGRLAM-IVTEYMENGSL 88 Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L H + QL+ + + GM YL YIHRDLAARN+L+D + K+ DFGL Sbjct 89 DAFLRTHDGQFTILQLVGMLKGVGAGMRYLSDLGYIHRDLAARNILVDGRLVCKVSDFGL 148 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 ++A+ + E G P+ W APE + F ASDVWSFGV ++E+L + + Sbjct 149 SRALEDDPEAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYW- 207 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 MT + +E G RLP P CP ++ LM +CW + + RP F + Sbjct 208 -------------NMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFSH 254 Query 1165 LIPILKT-VHEKYQGQAPSVFSVC 1187 ++ +L+ VH +A + S C Sbjct 255 VVSVLEALVHSPESLRATATVSRC 278 Score = 89.4 bits (220), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 80/286 (28%), Positives = 132/286 (46%), Gaps = 28/286 (10%) Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSH 667 ++ GSG E G++ VPG+ +++ V +K L + + F A++M Q H Sbjct 6 KIIGSG--ESGEVCYGRLQVPGQ---RDVPVAIKALKAGYTERQRQDFLREAAIMGQFDH 60 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 ++ + GV RG ++VTEY+E+G LD +LR G + + + + + + + YL + Sbjct 61 PNIIRLEGVVTRGRLAMIVTEYMENGSLDAFLRTHDGQFTILQLVGMLKGVGAGMRYLSD 120 Query 728 KNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIP--WL 779 +H ++ RNIL+ RL K+SD G+ E +IP W Sbjct 121 LGYIHRDLAARNILVDGRL--------VCKVSDFGLSRALEDDPEAAYTTAGGKIPIRWT 172 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838 APE + + S+A D W FG + E+ GE P + + + + +RLP P C Sbjct 173 APEAI--AFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNQDVISSVEEGYRLPAPMGC 230 Query 839 PQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVLTVN 881 P+ L L C + QRP F ++ L L P +L TV+ Sbjct 231 PRALHQLMLDCWHKDRAQRPRFSHVVSVLEALVHSPESLRATATVS 276 >sp|P04412|EGFR_DROME Epidermal growth factor receptor OS=Drosophila melanogaster OX=7227 GN=Egfr PE=1 SV=3 Length=1426 Score = 150 bits (379), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 94/275 (34%), Positives = 142/275 (52%), Gaps = 20/275 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+K LG G FG+V + P + VA+K L G + + +E I+ + H Sbjct 938 LRKGGVLGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASEEH 997 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYL 1014 +++K C + L+ + +PLG L DY+ R IG LL ++ QI +GM+YL Sbjct 998 VNLLKLLAVCM---SSQMMLITQLMPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYL 1054 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 + +HRDLAARNVL+ LVKI DFGLAK + Y+ G P+ W A EC++ Sbjct 1055 EEKRLVHRDLAARNVLVQTPSLVKITDFGLAKLLSSDSNEYKA-AGGKMPIKWLALECIR 1113 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 F SDVW+FGVT++ELLT Q P + + +L+E G +L Sbjct 1114 NRVFTSKSDVWAFGVTIWELLTF---GQRP-----------HENIPAKDIPDLIEVGLKL 1159 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 +P+ C ++Y + +CW +A+ RPTF+ L + Sbjct 1160 EQPEICSLDIYCTLLSCWHLDAAMRPTFKQLTTVF 1194 Score = 71.2 bits (173), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 93/413 (23%), Positives = 161/413 (39%), Gaps = 78/413 (19%) Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 P + + V E+ + LG G VY+G EG E+ +P Sbjct 920 PSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPEG-----------ENVKIP- 967 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 + ++L + + + F A +M+ H +L + VC+ + +++T+ + Sbjct 968 -------VAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKLLAVCMSS-QMMLITQLM 1019 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L ++R R + + + Q+A +SYLE K LVH ++ RN+L+ Sbjct 1020 PLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLVQ------- 1072 Query 751 TSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGATL 804 T +K++D G+ L + S E + I WLA EC+ ++ D W FG T+ Sbjct 1073 TPSLVKITDFGLAKLLSSDSNEYKAAGGKMPIKWLALECIRNRV--FTSKSDVWAFGVTI 1130 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL---ATLTSQCLTYEPTQRPSFRT 861 E+ G+ P ++ + + +L +P L TL S C + RP+F+ Sbjct 1131 WELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLS-CWHLDAAMRPTFKQ 1189 Query 862 IL-------RD-----------LTRLQPHNLAD----VLTVNPDSPASDPTVFHKRYLKK 899 + RD TRL + D + + P + S+ YL+ Sbjct 1190 LTTVFAEFARDPGRYLAIPGDKFTRLPAYTSQDEKDLIRKLAPTTDGSEAIAKPDDYLQP 1249 Query 900 IRDLGEGH-------FGKVSLYCYDPTN----------DGTGEMVAVKALKAD 935 G H K++ YC DP+N D + V V L+ D Sbjct 1250 KAAPGPSHRTDCTDEMPKLNRYCKDPSNKNSSTGDDERDSSAREVGVGNLRLD 1302 >sp|P00521|ABL_MLVAB Tyrosine-protein kinase transforming protein Abl OS=Abelson murine leukemia virus OX=11788 GN=ABL PE=3 SV=1 Length=746 Score = 148 bits (374), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 96/292 (33%), Positives = 148/292 (51%), Gaps = 35/292 (12%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 +D T+ HK LG G +G+V Y+ VAVK LK D + + Sbjct 126 TDITMKHK--------LGGGQYGEV----YEGVWKKYSLTVAVKTLKEDT--MEVEEFLK 171 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLF 1003 E +++ + H ++++ G C E ++ E++ G+L DYL R + LL Sbjct 172 EAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYM 229 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 A QI M YL +++IHRDLAARN L+ + LVK+ DFGL++ + + Y Sbjct 230 ATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDTYTAHAGAKF 287 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 P+ W APE L KF SDVW+FGV L+E+ T+ S P ++L + Sbjct 288 PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMS----PYPGIDLS----------Q 333 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 + ELLE+ R+ RP+ CP +VY LM+ CW+ S RP+F + +T+ ++ Sbjct 334 VYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 385 Score = 99.4 bits (246), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 73/249 (29%), Positives = 118/249 (47%), Gaps = 19/249 (8%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 L V +K L ++ F + A++M ++ H +L + GVC R P ++TE++ +G L Sbjct 152 LTVAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLL 210 Query 697 VWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +LR R V + +A Q++SA+ YLE KN +H ++ RN L+ G + + Sbjct 211 DYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV-------GENHLV 263 Query 756 KLSDPGVG---LGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ G + P W APE L N S D W FG L EI Sbjct 264 KVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESL--AYNKFSIKSDVWAFGVLLWEIATY 321 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL-T 867 G +P S+ ++ +R+ P CP+ + L C + P+ RPSF I + T Sbjct 322 GMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFET 381 Query 868 RLQPHNLAD 876 Q +++D Sbjct 382 MFQESSISD 390 >sp|P10936|YES_XENLA Tyrosine-protein kinase Yes OS=Xenopus laevis OX=8355 GN=yes1 PE=2 SV=3 Length=537 Score = 145 bits (366), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 94/276 (34%), Positives = 142/276 (51%), Gaps = 39/276 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+V + ++ T VA+K LK G + QE I++ L H+ ++ Sbjct 277 LGQGCFGEVWIGTWNGTTK-----VAIKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPL 329 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHY 1019 E+ + +V EY+ GSL D+L + + L QL+ A QI +GMAY+ +Y Sbjct 330 YAVVS---EEPIYIVTEYMIKGSLLDFLKEGNGKYLKLPQLVDMAAQIADGMAYIERMNY 386 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRDL A N+L+ ++ + KI DFGLA+ + + Y R+ P+ W APE +F Sbjct 387 IHRDLRAANILVGDNLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFT 444 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ-----MTVLRLTELLERGERL 1134 SDVWSFG+ L EL +A+G+ M + E +ERG R+ Sbjct 445 IKSDVWSFGILLTEL-------------------VAKGRVPYPGMVNREVLEQVERGYRM 485 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 P P +CP ++ LMK CW+ + RPTFE + L+ Sbjct 486 PCPQRCPESLHELMKLCWKKDPDERPTFEYIQSFLE 521 Score = 77.0 bits (188), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 65/233 (28%), Positives = 106/233 (45%), Gaps = 19/233 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P + AF + A +M ++ H L ++ V P I VTEY+ G L Sbjct 295 KVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEYMIKGSLLD 352 Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G ++ + + +A Q+A ++Y+E N +H ++ NIL+ G + K Sbjct 353 FLKEGNGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILV-------GDNLVCK 405 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVAKG 463 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTI 862 P E +R +R+P P CP+ L L C +P +RP+F I Sbjct 464 RVPYPGMVNREVLEQVERGYRMPCPQRCPESLHELMKLCWKKDPDERPTFEYI 516 >sp|Q90330|FGFR4_COTCO Fibroblast growth factor receptor 4 OS=Coturnix coturnix OX=9091 GN=FGFR4 PE=2 SV=1 Length=713 Score = 147 bits (372), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 106/323 (33%), Positives = 158/323 (49%), Gaps = 42/323 (13%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKAD 935 V D P F + L + LGEG FG+V Y D VAVK LK + Sbjct 361 VVEMDLPLDSKWEFPREKLVLGKPLGEGCFGQVVRAEAYGIDRQWPDRAVTVAVKMLKDN 420 Query 936 CGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---- 990 + + E+++++ + H++II G C G L +++E+ G+LR+YL Sbjct 421 ATDKDLADLISEMEMMKLMDKHKNIINLLGVCTQDG--PLYVIVEFAAKGNLREYLRARR 478 Query 991 ---PRHSIGLAQL----LLFAQ------QICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037 P ++ + +L L F Q+ GM YL ++ IHRDLAARNVL+ + ++ Sbjct 479 PPTPDYTFDITELHEEQLCFKDLVSCVYQVARGMEYLESRRCIHRDLAARNVLVTAENVM 538 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 KI DFGLA+ V +YY+ +G PV W APE L + + + SDVWSFG+ ++E+ T Sbjct 539 KIADFGLARDV-HDIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILMWEIFT- 596 Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157 L G + V L +LL+ G R+ P C E+Y LM+ CW Sbjct 597 -------------LGGSPYPGIPVEELFKLLKEGHRMDCPSNCTHELYMLMRECWHAVPL 643 Query 1158 FRPTFENLI----PILKTVHEKY 1176 RPTF+ L+ IL + E+Y Sbjct 644 QRPTFKQLVEGLDKILAAISEEY 666 Score = 65.1 bits (157), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 63/261 (24%), Positives = 112/261 (43%), Gaps = 32/261 (12%) Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 DR + V + + + D+A E + H ++ + GVC + ++ E+ Sbjct 407 DRAVTVAVKMLKDNATDKDLADLISEMEMMKLMDKHKNIINLLGVCTQDGPLYVIVEFAA 466 Query 692 HGPLDVWLRRERGHVP-------------MAWKMVVA--QQLASALSYLENKNLVHGNVC 736 G L +LR R P + +K +V+ Q+A + YLE++ +H ++ Sbjct 467 KGNLREYLRARRPPTPDYTFDITELHEEQLCFKDLVSCVYQVARGMEYLESRRCIHRDLA 526 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANS 790 RN+L+ AE +K++D G+ ++ R+P W+APE L + Sbjct 527 ARNVLVT----AENV---MKIADFGLARDVHDIDYYKKTSNGRLPVKWMAPEALFDRVYT 579 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQC 848 + D W FG + EI G +P E + HR+ PS C +L L +C Sbjct 580 HQS--DVWSFGILMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDCPSNCTHELYMLMREC 637 Query 849 LTYEPTQRPSFRTILRDLTRL 869 P QRP+F+ ++ L ++ Sbjct 638 WHAVPLQRPTFKQLVEGLDKI 658 >sp|Q2QLH6|MET_OTOGA Hepatocyte growth factor receptor OS=Otolemur garnettii OX=30611 GN=MET PE=3 SV=1 Length=1382 Score = 150 bits (378), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 146/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD + VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDENFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348 Score = 62.4 bits (150), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 101/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L + +K++D G+ +E Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------NFTVKVADFGLARDMYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341 >sp|A1A5H8|YES_DANRE Tyrosine-protein kinase yes OS=Danio rerio OX=7955 GN=yes1 PE=1 SV=1 Length=546 Score = 145 bits (365), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 106/334 (32%), Positives = 159/334 (48%), Gaps = 42/334 (13%) Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVL---------TVNPDSP--ASDPTVFHKRYLKK 899 Y T R F T+ + + H AD L TV P + A D + L+ Sbjct 225 YYITTRAQFDTLQKLVKHYTEH--ADGLCYRLTTVCPTVKPQTQGLAKDAWEIPRESLRL 282 Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG+V + ++ T VA+K LK G + QE I++ L H+ + Sbjct 283 ELKLGQGCFGEVWMGTWNGTTK-----VAIKTLKP--GTMSPEAFLQEAQIMKKLRHDKL 335 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA 1016 + E+ + +V EY+ GSL D+L + L QL+ A QI +GMA++ Sbjct 336 VPLYAVVS---EEPIYIVTEYMGKGSLLDFLKEGEGKYLKLPQLVDMAAQIADGMAFIER 392 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +YIHRDL A N+L+ ++ + KI DFGLA+ + + Y R+ P+ W APE Sbjct 393 MNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYG 450 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 +F SDVWSFG+ L EL+T + M + E +ERG R+P Sbjct 451 RFTIKSDVWSFGILLTELVTKGR--------------VPYPGMVNREVLEQVERGYRMPC 496 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 P CP ++ +M+ CW+ E RPTFE + L+ Sbjct 497 PQGCPESLHEMMRLCWKKEPDERPTFEYIQSFLE 530 Score = 75.1 bits (183), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 64/233 (27%), Positives = 105/233 (45%), Gaps = 19/233 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P AF + A +M ++ H L ++ V P I VTEY+ G L Sbjct 304 KVAIKTLKPGTMSPE-AFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEYMGKGSLLD 361 Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G ++ + + +A Q+A ++++E N +H ++ NIL+ G + K Sbjct 362 FLKEGEGKYLKLPQLVDMAAQIADGMAFIERMNYIHRDLRAANILV-------GDNLVCK 414 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 415 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 472 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 P E +R +R+P P CP+ L + C EP +RP+F I Sbjct 473 RVPYPGMVNREVLEQVERGYRMPCPQGCPESLHEMMRLCWKKEPDERPTFEYI 525 >sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens OX=9606 GN=ABL1 PE=1 SV=4 Length=1130 Score = 149 bits (375), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 97/300 (32%), Positives = 149/300 (50%), Gaps = 27/300 (9%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 TV SP D + + LG G +G+V Y+ VAVK LK D Sbjct 224 TVYGVSPNYDKWEMERTDITMKHKLGGGQYGEV----YEGVWKKYSLTVAVKTLKEDT-- 277 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSI 995 + +E +++ + H ++++ G C E ++ E++ G+L DYL R + Sbjct 278 MEVEEFLKEAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLDYLRECNRQEV 335 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 LL A QI M YL +++IHRDLAARN L+ + LVK+ DFGL++ + + Y Sbjct 336 NAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDTY 393 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 P+ W APE L KF SDVW+FGV L+E+ T+ S P ++L Sbjct 394 TAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMS----PYPGIDLS--- 446 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 ++ ELLE+ R+ RP+ CP +VY LM+ CW+ S RP+F + +T+ ++ Sbjct 447 -------QVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 499 Score = 98.2 bits (243), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 73/249 (29%), Positives = 118/249 (47%), Gaps = 19/249 (8%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 L V +K L ++ F + A++M ++ H +L + GVC R P ++TE++ +G L Sbjct 266 LTVAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLL 324 Query 697 VWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +LR R V + +A Q++SA+ YLE KN +H ++ RN L+ G + + Sbjct 325 DYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV-------GENHLV 377 Query 756 KLSDPGVG---LGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ G + P W APE L N S D W FG L EI Sbjct 378 KVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESL--AYNKFSIKSDVWAFGVLLWEIATY 435 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL-T 867 G +P S+ ++ +R+ P CP+ + L C + P+ RPSF I + T Sbjct 436 GMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFET 495 Query 868 RLQPHNLAD 876 Q +++D Sbjct 496 MFQESSISD 504 >sp|Q04912|RON_HUMAN Macrophage-stimulating protein receptor OS=Homo sapiens OX=9606 GN=MST1R PE=1 SV=3 Length=1400 Score = 149 bits (376), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 97/285 (34%), Positives = 151/285 (53%), Gaps = 24/285 (8%) Query 888 DPTVFHKRYLK-KIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWK 945 D + H+R + R +G+GHFG V Y + + + A+K+L Q + Sbjct 1072 DVLIPHERVVTHSDRVIGKGHFGVV--YHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFL 1129 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLF 1003 +E ++R L H +++ G E +++ Y+ G L ++ P+ + + L+ F Sbjct 1130 REGLLMRGLNHPNVLALIGIMLPP-EGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISF 1188 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 Q+ GM YL Q ++HRDLAARN +LD VK+ DFGLA+ + + EYY V++ + Sbjct 1189 GLQVARGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILD-REYYSVQQHRHA 1247 Query 1064 --PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 PV W A E L+ Y+F SDVWSFGV L+ELLT +PP + ++ Sbjct 1248 RLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLTR----GAPPYRHID----------P 1293 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 LT L +G RLP+P+ CP +Y +M+ CWE + + RPTF L+ Sbjct 1294 FDLTHFLAQGRRLPQPEYCPDSLYQVMQQCWEADPAVRPTFRVLV 1338 Score = 76.6 bits (187), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 64/235 (27%), Positives = 108/235 (46%), Gaps = 22/235 (9%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENI--MVTEYVEHGPLDVWLRRERGHVPMAWK 711 AF LM ++H ++ + G+ + PE + ++ Y+ HG L ++R + + + Sbjct 1127 AFLREGLLMRGLNHPNVLALIGIMLP-PEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDL 1185 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE- 770 + Q+A + YL + VH ++ RN +L S +K++D G+ L RE Sbjct 1186 ISFGLQVARGMEYLAEQKFVHRDLAARNCMLDE-------SFTVKVADFGLARDILDREY 1238 Query 771 -----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 R R+P W+A E L +T D W FG L E+ G P + P + Sbjct 1239 YSVQQHRHARLPVKWMALESL--QTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDL 1296 Query 824 EHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 HF + RLP+P CP L + QC +P RP+FR ++ ++ ++ L D Sbjct 1297 THFLAQGRRLPQPEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGD 1351 >sp|G5ECJ6|CSK1_CAEEL Tyrosine-protein kinase csk-1 OS=Caenorhabditis elegans OX=6239 GN=csk-1 PE=1 SV=1 Length=539 Score = 144 bits (364), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 89/274 (32%), Positives = 138/274 (50%), Gaps = 31/274 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V L Y VA+K K G E + L H +++ Sbjct 289 IGHGEFGDVRLGTY------KNRKVALKVSKRH-GNGMLDSLLDEAKFMVGLSHPNLVTL 341 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 G D + ++ ++ EY+ G+L D L RH++ QL++FA IC+GM YL ++ Sbjct 342 VGVVLD--DVNVYMITEYMANGNLIDLLRSRGRHALERRQLMMFAMDICQGMCYLESKQI 399 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLA-KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRDLAARNVLLD+D + K+ DFGLA KA + H+ G P+ W APE L+ +F Sbjct 400 VHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSHD----SASGKFPIKWTAPEALRHSQF 455 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SDVWSFG+ L+E+ + + ++ + + +E+G R+ P+ Sbjct 456 TTKSDVWSFGILLWEIFS--------------FGRVPYPRIPIQDVVRYIEKGYRMEAPE 501 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 CP E++ +M W A RP+F ++ L T+ Sbjct 502 GCPPEIFKVMNETWALSAQDRPSFGQVLQRLTTI 535 Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 67/241 (28%), Positives = 111/241 (46%), Gaps = 18/241 (7%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V LKV + + + + A M +SH +L + GV + M+TEY+ +G L + Sbjct 306 KVALKVSKRHGNGMLDSLLDEAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMANGNL-I 364 Query 698 WLRRERGHVPMAWK--MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 L R RG + + M+ A + + YLE+K +VH ++ RN+LL +A Sbjct 365 DLLRSRGRHALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVA------- 417 Query 756 KLSDPGVGLGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 K+SD G+ A S+ I W APE L + +T D W FG L EI G Sbjct 418 KVSDFGLAKKANSQSHDSASGKFPIKWTAPEALR--HSQFTTKSDVWSFGILLWEIFSFG 475 Query 812 EAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 P + + ++ +R+ PE P++ + ++ RPSF +L+ LT + Sbjct 476 RVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRLTTI 535 Query 870 Q 870 + Sbjct 536 R 536 >sp|Q60553|ERBB2_MESAU Receptor tyrosine-protein kinase erbB-2 OS=Mesocricetus auratus OX=10036 GN=ERBB2 PE=2 SV=1 Length=1254 Score = 149 bits (375), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 92/278 (33%), Positives = 142/278 (51%), Gaps = 20/278 (7%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 + + L+K++ LG G FG V + P + VA+K L+ + P+ E + Sbjct 714 ILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYV 773 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQIC 1008 + L ++ + G C ++QLV + +P G L D++ H +G LL + QI Sbjct 774 MAGLGSPYVSRLLGICL---TSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIA 830 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +GM+YL +HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W Sbjct 831 KGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWI 889 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A E + +F + SDVWS+GVT++EL+T GI + + +LL Sbjct 890 ALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYD---------GIPARE-----IPDLL 935 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 E+GERLP+P C +VY +M CW ++ RP F L+ Sbjct 936 EKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELV 973 Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 76/342 (22%), Positives = 142/342 (42%), Gaps = 46/342 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 +Q + + E+ ++ LG G VY+G +G E+ +P Sbjct 708 NQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDG-----------ENVKIP------- 749 Query 637 LRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +KVL + A + A +M+ + +++ + G+C+ +VT+ + +G L Sbjct 750 --VAIKVLRENTSPKANKEILDEAYVMAGLGSPYVSRLLGICLTSTVQ-LVTQLMPYGCL 806 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R RG + + Q+A +SYLE+ LVH ++ RN+L+ + + Sbjct 807 LDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVK-------SPNHV 859 Query 756 KLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 K++D GL L + E I W+A E + + D W +G T+ E+ Sbjct 860 KITD--FGLARLLDIDETEYHADGGKVPIKWIALESI--LRRRFTHQSDVWSYGVTVWEL 915 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRD 865 G P E ++ RLP+P + + +C + RP FR ++ + Sbjct 916 MTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSE 975 Query 866 LTRLQPHNLADVLTVNPDSPASDP--TVFHKRYLKKIRDLGE 905 +R+ V+ N D S P + F++ L+ D+G+ Sbjct 976 FSRMARDPQRFVVIQNEDLGPSSPLDSTFYRSLLED-DDMGD 1016 >sp|Q2QLF1|MET_PANTR Hepatocyte growth factor receptor OS=Pan troglodytes OX=9598 GN=MET PE=3 SV=1 Length=1390 Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 61.6 bits (148), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340 >sp|Q2IBD8|MET_PONAB Hepatocyte growth factor receptor OS=Pongo abelii OX=9601 GN=MET PE=3 SV=1 Length=1390 Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 61.6 bits (148), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340 >sp|Q2IBF2|MET_GORGO Hepatocyte growth factor receptor OS=Gorilla gorilla gorilla OX=9595 GN=MET PE=3 SV=1 Length=1390 Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 61.6 bits (148), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340 >sp|Q2IBA6|MET_CHLAE Hepatocyte growth factor receptor OS=Chlorocebus aethiops OX=9534 GN=MET PE=1 SV=1 Length=1381 Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 61.6 bits (148), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340 >sp|Q07DY1|MET_NOMLE Hepatocyte growth factor receptor OS=Nomascus leucogenys OX=61853 GN=MET PE=3 SV=1 Length=1390 Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 61.6 bits (148), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFT-------VKVADFGLARDMYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340 >sp|P39688|FYN_MOUSE Tyrosine-protein kinase Fyn OS=Mus musculus OX=10090 GN=Fyn PE=1 SV=4 Length=537 Score = 144 bits (363), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 91/277 (33%), Positives = 139/277 (50%), Gaps = 29/277 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ I+ LG G FG+V + ++ VA+K LK G + +E I++ L H Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAIKTLKP--GTMSPESFLEEAQIMKKLKH 323 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013 + +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 380 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + +YIHRDL + N+L+ N + KI DFGLA+ + + Y R+ P+ W APE Sbjct 381 IERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +F SDVWSFG+ L EL+T + M + E +ERG R Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +P P CP ++ LM +CW+ + RPTFE L L+ Sbjct 485 MPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLE 521 Score = 77.4 bits (189), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 65/230 (28%), Positives = 102/230 (44%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L Sbjct 295 KVAIKTLKPGTMSPE-SFLEEAQIMKKLKHDKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 352 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G K Sbjct 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GNGLICK 405 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 P + E +R +R+P P CP L L C +P +RP+F Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 513 >sp|Q2QLC0|MET_PLEMO Hepatocyte growth factor receptor OS=Plecturocebus moloch OX=9523 GN=MET PE=3 SV=1 Length=1381 Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 61.2 bits (147), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340 >sp|P08581|MET_HUMAN Hepatocyte growth factor receptor OS=Homo sapiens OX=9606 GN=MET PE=1 SV=4 Length=1390 Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 61.6 bits (148), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340 >sp|Q2QL89|MET_MICMU Hepatocyte growth factor receptor OS=Microcebus murinus OX=30608 GN=MET PE=3 SV=1 Length=1382 Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348 Score = 62.0 bits (149), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341 >sp|Q2IBG7|MET_EULMM Hepatocyte growth factor receptor OS=Eulemur macaco macaco OX=30603 GN=MET PE=3 SV=1 Length=1382 Score = 149 bits (375), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348 Score = 61.6 bits (148), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341 >sp|A0M8R7|MET_PAPAN Hepatocyte growth factor receptor OS=Papio anubis OX=9555 GN=MET PE=3 SV=1 Length=1381 Score = 148 bits (374), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 61.6 bits (148), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340 >sp|Q2QLG5|MET_CALJA Hepatocyte growth factor receptor OS=Callithrix jacchus OX=9483 GN=MET PE=3 SV=1 Length=1381 Score = 148 bits (374), Expect = 9e-35, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 61.6 bits (148), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340 >sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo sapiens OX=9606 GN=FYN PE=1 SV=3 Length=537 Score = 144 bits (363), Expect = 9e-35, Method: Compositional matrix adjust. Identities = 91/277 (33%), Positives = 139/277 (50%), Gaps = 29/277 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ I+ LG G FG+V + ++ VA+K LK G + +E I++ L H Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAIKTLKP--GTMSPESFLEEAQIMKKLKH 323 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013 + +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 380 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + +YIHRDL + N+L+ N + KI DFGLA+ + + Y R+ P+ W APE Sbjct 381 IERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +F SDVWSFG+ L EL+T + M + E +ERG R Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +P P CP ++ LM +CW+ + RPTFE L L+ Sbjct 485 MPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLE 521 Score = 77.4 bits (189), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 65/230 (28%), Positives = 102/230 (44%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L Sbjct 295 KVAIKTLKPGTMSPE-SFLEEAQIMKKLKHDKLVQLYAVVSEEPIYI-VTEYMNKGSLLD 352 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G K Sbjct 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GNGLICK 405 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 P + E +R +R+P P CP L L C +P +RP+F Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 513 >sp|Q07DV8|MET_AOTNA Hepatocyte growth factor receptor OS=Aotus nancymaae OX=37293 GN=MET PE=3 SV=1 Length=1381 Score = 148 bits (374), Expect = 9e-35, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS--PVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 61.2 bits (147), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340 >sp|Q09YH7|MET_SAIBB Hepatocyte growth factor receptor OS=Saimiri boliviensis boliviensis OX=39432 GN=MET PE=3 SV=1 Length=1381 Score = 148 bits (374), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 61.2 bits (147), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340 >sp|Q07DZ1|MET_COLGU Hepatocyte growth factor receptor OS=Colobus guereza OX=33548 GN=MET PE=3 SV=1 Length=1381 Score = 148 bits (374), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 61.6 bits (148), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340 >sp|A1Y2K1|FYN_PIG Tyrosine-protein kinase Fyn OS=Sus scrofa OX=9823 GN=FYN PE=2 SV=2 Length=537 Score = 144 bits (363), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 91/277 (33%), Positives = 139/277 (50%), Gaps = 29/277 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ I+ LG G FG+V + ++ VA+K LK G + +E I++ L H Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAIKTLKP--GTMSPESFLEEAQIMKKLKH 323 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013 + +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 380 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + +YIHRDL + N+L+ N + KI DFGLA+ + + Y R+ P+ W APE Sbjct 381 IERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +F SDVWSFG+ L EL+T + M + E +ERG R Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +P P CP ++ LM +CW+ + RPTFE L L+ Sbjct 485 MPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLE 521 Score = 77.4 bits (189), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 65/230 (28%), Positives = 102/230 (44%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L Sbjct 295 KVAIKTLKPGTMSPE-SFLEEAQIMKKLKHDKLVQLYAVVSEEPIYI-VTEYMNKGSLLD 352 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G K Sbjct 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GNGLICK 405 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 P + E +R +R+P P CP L L C +P +RP+F Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 513 >sp|P00520|ABL1_MOUSE Tyrosine-protein kinase ABL1 OS=Mus musculus OX=10090 GN=Abl1 PE=1 SV=3 Length=1123 Score = 148 bits (373), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 98/292 (34%), Positives = 147/292 (50%), Gaps = 35/292 (12%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 +D T+ HK LG G +G+V Y+ VAVK LK D + + Sbjct 240 TDITMKHK--------LGGGQYGEV----YEGVWKKYSLTVAVKTLKEDT--MEVEEFLK 285 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLF 1003 E +++ + H ++++ G C E ++ E++ G+L DYL R + LL Sbjct 286 EAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYM 343 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 A QI M YL +++IHRDLAARN L+ + LVK+ DFGL++ + + Y Sbjct 344 ATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDTYTAHAGAKF 401 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 P+ W APE L KF SDVW+FGV L+E+ T+ SP GI Q Sbjct 402 PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATY---GMSP------YPGIDLSQ----- 447 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 + ELLE+ R+ RP+ CP +VY LM+ CW+ S RP+F + +T+ ++ Sbjct 448 VYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 499 Score = 98.2 bits (243), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 73/249 (29%), Positives = 118/249 (47%), Gaps = 19/249 (8%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 L V +K L ++ F + A++M ++ H +L + GVC R P ++TE++ +G L Sbjct 266 LTVAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLL 324 Query 697 VWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +LR R V + +A Q++SA+ YLE KN +H ++ RN L+ G + + Sbjct 325 DYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV-------GENHLV 377 Query 756 KLSDPGVG---LGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ G + P W APE L N S D W FG L EI Sbjct 378 KVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESL--AYNKFSIKSDVWAFGVLLWEIATY 435 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL-T 867 G +P S+ ++ +R+ P CP+ + L C + P+ RPSF I + T Sbjct 436 GMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFET 495 Query 868 RLQPHNLAD 876 Q +++D Sbjct 496 MFQESSISD 504 >sp|Q09YL1|MET_ATEGE Hepatocyte growth factor receptor OS=Ateles geoffroyi OX=9509 GN=MET PE=3 SV=1 Length=1381 Score = 148 bits (374), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T NDG AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSAFIGE 1347 Score = 61.2 bits (147), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340 >sp|Q62844|FYN_RAT Tyrosine-protein kinase Fyn OS=Rattus norvegicus OX=10116 GN=Fyn PE=1 SV=1 Length=537 Score = 144 bits (362), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 91/277 (33%), Positives = 139/277 (50%), Gaps = 29/277 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ I+ LG G FG+V + ++ VA+K LK G + +E I++ L H Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAIKTLKP--GTMSPESFLEEAQIMKKLKH 323 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013 + +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 380 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + +YIHRDL + N+L+ N + KI DFGLA+ + + Y R+ P+ W APE Sbjct 381 IERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +F SDVWSFG+ L EL+T + M + E +ERG R Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +P P CP ++ LM +CW+ + RPTFE L L+ Sbjct 485 MPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLE 521 Score = 77.4 bits (189), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 65/230 (28%), Positives = 102/230 (44%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L Sbjct 295 KVAIKTLKPGTMSPE-SFLEEAQIMKKLKHDKLVQLYAVVSEEPIYI-VTEYMNKGSLLD 352 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G K Sbjct 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GNGLICK 405 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 P + E +R +R+P P CP L L C +P +RP+F Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 513 >sp|A0JNB0|FYN_BOVIN Tyrosine-protein kinase Fyn OS=Bos taurus OX=9913 GN=FYN PE=2 SV=1 Length=537 Score = 144 bits (362), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 91/277 (33%), Positives = 139/277 (50%), Gaps = 29/277 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ I+ LG G FG+V + ++ VA+K LK G + +E I++ L H Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAIKTLKP--GTMSPESFLEEAQIMKKLKH 323 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013 + +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAY 380 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + +YIHRDL + N+L+ N + KI DFGLA+ + + Y R+ P+ W APE Sbjct 381 IERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +F SDVWSFG+ L EL+T + M + E +ERG R Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +P P CP ++ LM +CW+ + RPTFE L L+ Sbjct 485 MPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLE 521 Score = 77.4 bits (189), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 65/230 (28%), Positives = 102/230 (44%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L Sbjct 295 KVAIKTLKPGTMSPE-SFLEEAQIMKKLKHDKLVQLYAVVSEEPIYI-VTEYMNKGSLLD 352 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G K Sbjct 353 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GNGLICK 405 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 P + E +R +R+P P CP L L C +P +RP+F Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 513 >sp|Q16832|DDR2_HUMAN Discoidin domain-containing receptor 2 OS=Homo sapiens OX=9606 GN=DDR2 PE=1 SV=2 Length=855 Score = 147 bits (370), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 96/298 (32%), Positives = 143/298 (48%), Gaps = 34/298 (11%) Query 892 FHKRYLKKIRDLGEGHFGKVSL-------------YCYDPTNDGTGEMVAVKALKADCGP 938 F ++ L LGEG FG+V L + D + + +VAVK L+AD Sbjct 558 FPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN-QPVLVAVKMLRADANK 616 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----- 993 R+ + +EI I+ L +II C + L ++ EY+ G L +L RH Sbjct 617 NARNDFLKEIKIMSRLKDPNIIHLLAVC--ITDDPLCMITEYMENGDLNQFLSRHEPPNS 674 Query 994 ------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 ++ L A QI GM YL + +++HRDLA RN L+ + +KI DFG+++ Sbjct 675 SSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRN 734 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + G +YYR++ P+ W + E + KF ASDVW+FGVTL+E T C Q P Sbjct 735 LYSG-DYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC---QEQPYS 790 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L + + R R LP+P CP VY LM +CW + RP+F+ + Sbjct 791 QLSDEQVIENTGEFFRDQ---GRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEI 845 Score = 72.0 bits (175), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 71/255 (28%), Positives = 113/255 (44%), Gaps = 35/255 (14%) Query 634 GQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 Q + V +K+L + A F + +MS++ ++ + VC+ M+TEY+E+ Sbjct 600 NQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMEN 659 Query 693 GPLDVWLRR---------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 G L+ +L R + V +A Q+AS + YL + N VH ++ RN L+ Sbjct 660 GDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLV- 718 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDK 797 G + IK++D G+ S + V I W++ E + G +TA D Sbjct 719 ------GKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLG--KFTTASDV 770 Query 798 WGFGATLLE-ICFDGEAPLQSRSPSE----KEHFYQ---RQHRLPEPS-CPQ-LATLTSQ 847 W FG TL E F E P S + F++ RQ LP+P+ CP + L Sbjct 771 WAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLS 830 Query 848 CLTYEPTQRPSFRTI 862 C + RPSF+ I Sbjct 831 CWRRDTKNRPSFQEI 845 >sp|P31693|SRC_RSVPA Tyrosine-protein kinase transforming protein Src OS=Rous sarcoma virus (strain PA101T) OX=31667 GN=V-SRC PE=3 SV=3 Length=523 Score = 143 bits (361), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 100/301 (33%), Positives = 151/301 (50%), Gaps = 34/301 (11%) Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 H L +V T P + A D + L+ LG+G+FG+V + ++ T VA Sbjct 236 HRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGYFGEVWMGTWNGTT-----RVA 290 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL D Sbjct 291 IKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAMV---SEEPIYIVIEYMSKGSLLD 345 Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 346 FL-KGEMGKYLRLPQLVEMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 404 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R PV W APE +F SDVWSFG+ L EL T Sbjct 405 ARLIEDNE--YTARPGARFPVKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 457 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + G+ G+ + + +ERG R+P P +CP ++ LM CW + RPTFE Sbjct 458 ----VPYPGMVNGE-----VLDRVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEY 508 Query 1165 L 1165 L Sbjct 509 L 509 Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 67/231 (29%), Positives = 107/231 (46%), Gaps = 21/231 (9%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ + P I++ EY+ G L Sbjct 288 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAMVSEEPIYIVI-EYMSKGSLLD 345 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 346 FLKGEMGKYLRLPQLVEMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 398 Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 ++D G+ + E R + W APE G ++ + D W FG L E+ Sbjct 399 VADFGLAR-LIEDNEYTARPGARFPVKWTAPEAALYGRFTIKS--DVWSFGILLTELTTK 455 Query 811 GEAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859 G P E +R +R+P P CP+ L L QC +P +RP+F Sbjct 456 GRVPYPGMVNGEVLDRVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTF 506 >sp|O18735|ERBB2_CANLF Receptor tyrosine-protein kinase erbB-2 OS=Canis lupus familiaris OX=9615 GN=ERBB2 PE=2 SV=1 Length=1259 Score = 147 bits (372), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 89/278 (32%), Positives = 140/278 (50%), Gaps = 20/278 (7%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 + + L+K++ LG G FG V + P + VA+K L+ + P+ E + Sbjct 713 ILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYV 772 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQIC 1008 + + ++ + G C ++QLV + +P G L D++ H +G LL + QI Sbjct 773 MAGVGSPYVSRLLGICL---TSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIA 829 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +GM+YL +HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W Sbjct 830 KGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWM 888 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A E + +F + SDVWS+GVT++EL+T + + +LL Sbjct 889 ALESIPPRRFTHQSDVWSYGVTVWELMT--------------FGAKPYDGIPAREIPDLL 934 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 E+GERLP+P C +VY +M CW ++ RP F L+ Sbjct 935 EKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELV 972 Score = 68.6 bits (166), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 84/366 (23%), Positives = 148/366 (40%), Gaps = 50/366 (14%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 +Q + + E+ ++ LG G VY+G +G E+ +P Sbjct 707 NQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDG-----------ENVKIP------- 748 Query 637 LRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +KVL + A + A +M+ V +++ + G+C+ +VT+ + +G L Sbjct 749 --VAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQLMPYGCL 805 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R RG + + Q+A +SYLE+ LVH ++ RN+L+ + + Sbjct 806 LDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVK-------SPNHV 858 Query 756 KLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 K++D GL L + E I W+A E +P + D W +G T+ E+ Sbjct 859 KITD--FGLARLLDIDETEYHADGGKVPIKWMALESIP--PRRFTHQSDVWSYGVTVWEL 914 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRD 865 G P E ++ RLP+P + + +C + RP FR ++ + Sbjct 915 MTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVAE 974 Query 866 LTRLQPHNLADVLTVNPD-SPASDPTVFHKRYLKKIRDLG------EGHFGKVSLYCYDP 918 +R+ V+ N D PAS R L + D+G E + +C +P Sbjct 975 FSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPEP 1034 Query 919 TNDGTG 924 T G Sbjct 1035 TPGAGG 1040 >sp|P29318|EPHA3_CHICK Ephrin type-A receptor 3 OS=Gallus gallus OX=9031 GN=EPHA3 PE=1 SV=1 Length=983 Score = 147 bits (371), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 87/270 (32%), Positives = 141/270 (52%), Gaps = 21/270 (8%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG+V S P+ VA+K LKA + R + E I+ H +II+ Sbjct 627 VGAGEFGEVCSGRLKLPSKKEIS--VAIKTLKAGYTEKQRRDFLGEASIMGQFDHPNIIR 684 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHY 1019 +G K + +V EY+ GSL +L +H + QL+ + I GM YL Y Sbjct 685 LEGVVTKS--KPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGY 742 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W +PE + KF Sbjct 743 VHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFT 802 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 ASD WS+G+ L+E++++ + P +M+ + + ++ G RLP P Sbjct 803 SASDAWSYGIVLWEVMSY---GERP-----------YWEMSFQDVIKAVDEGYRLPPPMD 848 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 CP +Y LM +CW+ + + RP FE ++ IL Sbjct 849 CPAALYQLMLDCWQKDRNNRPKFEQIVSIL 878 Score = 86.7 bits (213), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 68/245 (28%), Positives = 110/245 (45%), Gaps = 19/245 (8%) Query 635 QELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +E+ V +K L + + F AS+M Q H ++ + GV + ++VTEY+E+G Sbjct 646 KEISVAIKTLKAGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENG 705 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 LD +LR+ + + + + +AS + YL + VH ++ RNIL+ ++ Sbjct 706 SLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILI-------NSNL 758 Query 754 FIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLE 806 K+SD G+ E R +IP W +PE + ++A D W +G L E Sbjct 759 VCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAI--AYRKFTSASDAWSYGIVLWE 816 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILR 864 + GE P S + +RLP P CP L L C + RP F I+ Sbjct 817 VMSYGERPYWEMSFQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVS 876 Query 865 DLTRL 869 L +L Sbjct 877 ILDKL 881 >sp|Q1JPZ3|SRC_DANRE Proto-oncogene tyrosine-protein kinase Src OS=Danio rerio OX=7955 GN=src PE=1 SV=2 Length=534 Score = 143 bits (361), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 101/306 (33%), Positives = 151/306 (49%), Gaps = 34/306 (11%) Query 872 HNLADVLTV-NPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 H+L DV V P + A D + L+ LG+G FG+V + ++ T VA Sbjct 240 HSLTDVCPVLKPPTQGLARDAWEIPRDSLRLDVKLGQGCFGEVWMGTWNGTT-----RVA 294 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK G + QE +++ L HE +++ E+ + +V EY+ GSL D Sbjct 295 IKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS---EEPIYIVTEYMGQGSLLD 349 Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ ++ + K+ DFGL Sbjct 350 FL-KGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGL 408 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 409 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 461 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW E RPTFE Sbjct 462 ---------VPYPGMVNREVLDQVERGYRMPCPAECPDSLHELMLTCWRKEPEERPTFEY 512 Query 1165 LIPILK 1170 L L+ Sbjct 513 LQGFLE 518 Score = 79.3 bits (194), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 69/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L Sbjct 292 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMGQGSLLD 349 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ + G + ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 350 FLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILV-------GDNLVCK 402 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 403 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 460 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSF 859 P E +R +R+P P+ CP L L C EP +RP+F Sbjct 461 RVPYPGMVNREVLDQVERGYRMPCPAECPDSLHELMLTCWRKEPEERPTF 510 >sp|Q26614|FGFR_STRPU Fibroblast growth factor receptor OS=Strongylocentrotus purpuratus OX=7668 GN=FGFR PE=2 SV=1 Length=972 Score = 147 bits (370), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 99/304 (33%), Positives = 150/304 (49%), Gaps = 45/304 (15%) Query 892 FHKRYLKKIRDLGEGHFGKV------SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 F + L + +GEG FGKV + C + T+ VAVK LKA+ + S Sbjct 634 FPRDRLTVGKTIGEGAFGKVVIGEAVGIVCQEKTS-----TVAVKMLKANAMDREFSDLI 688 Query 946 QEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------------- 990 E+ +++ + + +II GCC +G +++E+ G+LRD+L Sbjct 689 SELAMMKMIGKNPNIINLLGCCTQEGPP--YVIVEFAHHGNLRDFLRSRRPPEEYEKSIL 746 Query 991 --PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 ++ L+ A Q+ GM +L ++ IHRDLAARNVL+ D +KI DFGLA+ + Sbjct 747 LTTSQTLTNKDLMSMAYQVARGMDFLASKKCIHRDLAARNVLVTEDFEMKICDFGLARDI 806 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 ++YR DG PV W APE L + F SDVWSFG+ L+E++T Sbjct 807 -HYIDFYRKTTDGRLPVKWMAPEALFDRMFTTQSDVWSFGILLWEIMT------------ 853 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 L G + V ++ + L G+RL +P E+YH++ CW T RPTF L+ Sbjct 854 --LGGTPYPSVPVEQMFDYLRSGKRLEKPQNTSLEIYHILCECWRTSPGQRPTFCELVED 911 Query 1169 LKTV 1172 L + Sbjct 912 LDRI 915 Score = 60.1 bits (144), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 60/221 (27%), Positives = 94/221 (43%), Gaps = 39/221 (18%) Query 675 GVCVR-GPENIMVTEYVEHGPLDVWLRRERGHVPMAWK----------------MVVAQQ 717 G C + GP ++V E+ HG L +LR R P ++ M +A Q Sbjct 708 GCCTQEGPPYVIV-EFAHHGNLRDFLRSRRP--PEEYEKSILLTTSQTLTNKDLMSMAYQ 764 Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF-IKLSDPGVGLGA----LSREER 772 +A + +L +K +H ++ RN+L+ T F +K+ D G+ R+ Sbjct 765 VARGMDFLASKKCIHRDLAARNVLV--------TEDFEMKICDFGLARDIHYIDFYRKTT 816 Query 773 VERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 R+P W+APE L +T D W FG L EI G P S + + + Sbjct 817 DGRLPVKWMAPEAL--FDRMFTTQSDVWSFGILLWEIMTLGGTPYPSVPVEQMFDYLRSG 874 Query 831 HRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869 RL +P L + +C P QRP+F ++ DL R+ Sbjct 875 KRLEKPQNTSLEIYHILCECWRTSPGQRPTFCELVEDLDRI 915 >sp|P51813|BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX OS=Homo sapiens OX=9606 GN=BMX PE=1 SV=1 Length=675 Score = 145 bits (366), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 93/278 (33%), Positives = 139/278 (50%), Gaps = 27/278 (10%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +++LG G FG V L + D VAVK +K G + QE + L H + Sbjct 420 LKELGSGQFGVVQLGKWKGQYD-----VAVKMIKE--GSMSEDEFFQEAQTMMKLSHPKL 472 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQ 1017 +K+ G C E + +V EY+ G L +YL H GL +QLL +CEGMA+L + Sbjct 473 VKFYGVCSK--EYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESH 530 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +IHRDLAARN L+D D VK+ DFG+ + V + Y PV W APE +K Sbjct 531 QFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQ--YVSSVGTKFPVKWSAPEVFHYFK 588 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + SDVW+FG+ ++E+ + + P + VL++++ G RL RP Sbjct 589 YSSKSDVWAFGILMWEVFS---LGKQP-------YDLYDNSQVVLKVSQ----GHRLYRP 634 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 +Y +M +CW RPTF+ L+ ++ + EK Sbjct 635 HLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLREK 672 Score = 65.5 bits (158), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 54/224 (24%), Positives = 98/224 (44%), Gaps = 18/224 (8%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F++ A M ++SH L +GVC + +VTEY+ +G L +LR + + + + Sbjct 457 FFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEM 516 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + +++LE+ +H ++ RN L+ R +K+SD G+ L ++ V Sbjct 517 CYDVCEGMAFLESHQFIHRDLAARNCLVDR-------DLCVKVSDFGMTRYVLD-DQYVS 568 Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 + W APE S+ D W FG + E+ G+ P S+ Sbjct 569 SVGTKFPVKWSAPEVF--HYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVS 626 Query 829 RQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + HRL P + + + C P +RP+F+ +L + L+ Sbjct 627 QGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLR 670 >sp|Q05688|IGF1R_BOVIN Insulin-like growth factor 1 receptor (Fragment) OS=Bos taurus OX=9913 GN=IGF1R PE=2 SV=1 Length=640 Score = 144 bits (364), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 95/286 (33%), Positives = 144/286 (50%), Gaps = 29/286 (10%) Query 901 RDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 R+LG+G FG V D VA+K + + R + E +++ H+ Sbjct 276 RELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHV 335 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIG-------LAQLLLFAQQIC 1008 ++ G QG+ +L ++ME + G L+ YL P L++++ A +I Sbjct 336 VRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIA 393 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +GMAYL+A ++HRDLAARN ++ D VKIGDFG+ + + E +YYR G PV W Sbjct 394 DGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYE-TDYYRKGGKGLLPVRWM 452 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 +PE LK+ F SDVWSFGV L+E+ T + G++ Q VLR + Sbjct 453 SPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQ---------GLSNEQ--VLR---FV 498 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 G L +PD CP ++ LM+ CW+ RP+F +I +K E Sbjct 499 MEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSVKDEME 544 Score = 84.0 bits (206), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 79/301 (26%), Positives = 127/301 (42%), Gaps = 46/301 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +++IT LGQG+ VYEG + G + DE E RV +K Sbjct 267 VAREKITMSRELGQGSFGMVYEGVAK---------GVVKDE----------PETRVAIKT 307 Query 644 LD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 ++ + + F AS+M + + H+ + GV +G +++ E + G L +LR Sbjct 308 VNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSL 367 Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 R + P KM+ +A ++A ++YL VH ++ RN ++A Sbjct 368 RPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAE-------DF 420 Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+ D G+ + + + + W++PE L G +T D W FG L EI Sbjct 421 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTHSDVWSFGVVLWEI 478 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRD 865 E P Q S + F L +P +CP L L C Y P RPSF I+ Sbjct 479 ATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISS 538 Query 866 L 866 + Sbjct 539 V 539 >sp|P06494|ERBB2_RAT Receptor tyrosine-protein kinase erbB-2 OS=Rattus norvegicus OX=10116 GN=Erbb2 PE=1 SV=3 Length=1257 Score = 147 bits (371), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 89/278 (32%), Positives = 140/278 (50%), Gaps = 20/278 (7%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 + + L+K++ LG G FG V + P + VA+K L+ + P+ E + Sbjct 716 ILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYV 775 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQIC 1008 + + ++ + G C ++QLV + +P G L D++ H +G LL + QI Sbjct 776 MAGVGSPYVSRLLGICL---TSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIA 832 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +GM+YL +HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W Sbjct 833 KGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWM 891 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A E + +F + SDVWS+GVT++EL+T + + +LL Sbjct 892 ALESILRRRFTHQSDVWSYGVTVWELMT--------------FGAKPYDGIPAREIPDLL 937 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 E+GERLP+P C +VY +M CW ++ RP F L+ Sbjct 938 EKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELV 975 Score = 64.3 bits (155), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 77/342 (23%), Positives = 142/342 (42%), Gaps = 46/342 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 +Q + + E+ ++ LG G VY+G +G E+ +P Sbjct 710 NQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDG-----------ENVKIP------- 751 Query 637 LRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +KVL + A + A +M+ V +++ + G+C+ +VT+ + +G L Sbjct 752 --VAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQLMPYGCL 808 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R RG + + Q+A +SYLE+ LVH ++ RN+L+ + + Sbjct 809 LDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVK-------SPNHV 861 Query 756 KLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 K++D GL L + E I W+A E + + D W +G T+ E+ Sbjct 862 KITD--FGLARLLDIDETEYHADGGKVPIKWMALESI--LRRRFTHQSDVWSYGVTVWEL 917 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRD 865 G P E ++ RLP+P + + +C + RP FR ++ + Sbjct 918 MTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSE 977 Query 866 LTRLQPHNLADVLTVNPDSPASDP--TVFHKRYLKKIRDLGE 905 +R+ V+ N D S P + F++ L+ D+G+ Sbjct 978 FSRMARDPQRFVVIQNEDLGPSSPMDSTFYRSLLED-DDMGD 1018 >sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens OX=9606 GN=SRC PE=1 SV=3 Length=536 Score = 143 bits (360), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 91/271 (34%), Positives = 136/271 (50%), Gaps = 29/271 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++ Sbjct 276 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQL 328 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHY 1019 E+ + +V EY+ GSL D+L + + L QL+ A QI GMAY+ +Y Sbjct 329 YAVVS---EEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNY 385 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F Sbjct 386 VHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFT 443 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SDVWSFG+ L EL T + M + + +ERG R+P P + Sbjct 444 IKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPPE 489 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 CP ++ LM CW E RPTFE L L+ Sbjct 490 CPESLHDLMCQCWRKEPEERPTFEYLQAFLE 520 Score = 83.6 bits (205), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 71/230 (31%), Positives = 106/230 (46%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L Sbjct 294 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 351 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 352 FLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 404 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 405 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 462 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859 P E +R +R+P P CP+ L L QC EP +RP+F Sbjct 463 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTF 512 >sp|O13148|EPA4A_DANRE Ephrin type-A receptor 4a (Fragment) OS=Danio rerio OX=7955 GN=epha4a PE=2 SV=1 Length=292 Score = 137 bits (345), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 79/254 (31%), Positives = 132/254 (52%), Gaps = 27/254 (11%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VA+K LKA + R + E I+ H +II+ +G K + ++ EY+ GSL Sbjct 24 VAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIRLEGVVTKC--KPVMIITEYMENGSL 81 Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L ++ + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFG+ Sbjct 82 DAFLRKNDGRFTVIQLVGILRGIASGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGM 141 Query 1045 AKAVPEGHE-YYRVRE--------DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 ++ + E + Y RE G P+ W APE + KF ASDVWS+G+ ++E++ Sbjct 142 SRVLEEDPDAAYTTREITGTYQSQGGKIPIRWTAPEAITYRKFTSASDVWSYGIVMWEVM 201 Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155 ++ + M+ + + +E G RLP P CP ++ LM +CW+ E Sbjct 202 SYGER--------------PYWDMSNQDVIKAIEEGYRLPPPMDCPVSLHQLMLDCWQKE 247 Query 1156 ASFRPTFENLIPIL 1169 + RP F ++ +L Sbjct 248 RAERPKFSQIVNML 261 Score = 93.2 bits (230), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 76/276 (28%), Positives = 125/276 (45%), Gaps = 40/276 (14%) Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 +PG+ +E+ V +K L + D F AS+M Q H ++ + GV + +++ Sbjct 16 MPGK---REICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIRLEGVVTKCKPVMII 72 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TEY+E+G LD +LR+ G + + + + +AS + YL + + VH ++ RNIL+ Sbjct 73 TEYMENGSLDAFLRKNDGRFTVIQLVGILRGIASGMKYLSDMSYVHRDLAARNILV---- 128 Query 747 LAEGTSPFIKLSDPGVG--------LGALSRE------ERVERIP--WLAPECLPGGANS 790 ++ K+SD G+ +RE + +IP W APE + Sbjct 129 ---NSNLVCKVSDFGMSRVLEEDPDAAYTTREITGTYQSQGGKIPIRWTAPEAIT--YRK 183 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQC 848 ++A D W +G + E+ GE P S + + +RLP P CP L L C Sbjct 184 FTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPVSLHQLMLDC 243 Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884 E +RP F I+ N+ D L NP+S Sbjct 244 WQKERAERPKFSQIV---------NMLDKLIRNPNS 270 >sp|Q25410|MIPR_LYMST Putative molluscan insulin-related peptide(s) receptor OS=Lymnaea stagnalis OX=6523 PE=2 SV=1 Length=1607 Score = 147 bits (371), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 107/350 (31%), Positives = 169/350 (48%), Gaps = 42/350 (12%) Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901 +L C+ Y+ R T++ P +++L + SD + +K I+ Sbjct 991 VSLIVACVYYKQKIRSDDMTVISRNMNYVP---SEILYI------SDEWEVDRDKIKLIK 1041 Query 902 DLGEGHFGKVSLYCYDPTNDGTGEM--VAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +LG+G FG V D E VAVK + R + +E ++ + H+ Sbjct 1042 ELGQGSFGMVYEGVAKGIRDDPNEEIPVAVKTVNDRASFSDRREFLKEATTMKEFHCHHV 1101 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----------LAQLLLFAQQICE 1009 +K G G+ +L ++ME + LG L++YL H L +L A +I + Sbjct 1102 VKLLGVVS-TGQPAL-VIMELMALGDLKNYLRGHRPDEDHPGVMPPHLLDILQMAGEIAD 1159 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 GMAYL + ++HRDLAARN ++ +R VKIGDFG+ + + E +YYR G PV W A Sbjct 1160 GMAYLADKKFVHRDLAARNCMVSEERTVKIGDFGMTRDIYET-DYYRKGGKGMLPVRWMA 1218 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE LK+ F SDVWS+GV ++E++T L ++ + + + Sbjct 1219 PESLKDGVFTSLSDVWSYGVVMWEMVT--------------LAAQPYQGLSNEEVVKFIS 1264 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTF----ENLIPILKTVHEK 1175 G + P+ CP E+ +LM++CW + + RPTF E L+P LK EK Sbjct 1265 DGYIMELPENCPNEMAYLMQHCWAKKPNQRPTFKAIIEYLLPKLKPSFEK 1314 Score = 79.3 bits (194), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 79/306 (26%), Positives = 134/306 (44%), Gaps = 45/306 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 VD+ +I + LGQG+ VYEG + G DD + +P V V Sbjct 1032 VDRDKIKLIKELGQGSFGMVYEGVAK---------GIRDDPNEEIP--------VAVKTV 1074 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 D + F + A+ M + H+ + GV G +++ E + G L +LR R Sbjct 1075 NDRASFSDRREFLKEATTMKEFHCHHVVKLLGVVSTGQPALVIMELMALGDLKNYLRGHR 1134 Query 704 ------GHVP--MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 G +P + + +A ++A ++YL +K VH ++ RN +++ E T + Sbjct 1135 PDEDHPGVMPPHLLDILQMAGEIADGMAYLADKKFVHRDLAARNCMVSE----ERT---V 1187 Query 756 KLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 K+ D G+ + + + + W+APE L G ++ D W +G + E+ Sbjct 1188 KIGDFGMTRDIYETDYYRKGGKGMLPVRWMAPESLKDGV--FTSLSDVWSYGVVMWEMVT 1245 Query 810 DGEAPLQSRSPSEKEHFYQRQH--RLPEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDL 866 P Q S E F + LPE +CP ++A L C +P QRP+F+ I+ L Sbjct 1246 LAAQPYQGLSNEEVVKFISDGYIMELPE-NCPNEMAYLMQHCWAKKPNQRPTFKAIIEYL 1304 Query 867 T-RLQP 871 +L+P Sbjct 1305 LPKLKP 1310 >sp|P03949|ABL1_CAEEL Tyrosine-protein kinase abl-1 OS=Caenorhabditis elegans OX=6239 GN=abl-1 PE=1 SV=4 Length=1224 Score = 147 bits (371), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 99/266 (37%), Positives = 136/266 (51%), Gaps = 27/266 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G +G V Y +D T +AVKALK D P H + E I++ L+H+++++ Sbjct 317 LGGGQYGDV-YEGYWKRHDCT---IAVKALKEDAMPLHE--FLAEAAIMKDLHHKNLVRL 370 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLHAQHY 1019 G C E ++ E++ G+L +YL R L L+ A QI GM+YL A+H+ Sbjct 371 LGVC--THEAPFYIITEFMCNGNLLEYLRRTDKSLLPPIILVQMASQIASGMSYLEARHF 428 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRDLAARN L+ +VKI DFGLA+ + E + Y P+ W APE L F Sbjct 429 IHRDLAARNCLVSEHNIVKIADFGLARFMKE--DTYTAHAGAKFPIKWTAPEGLAFNTFS 486 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SDVW+FGV L+E+ T+ P +EL + LLE G R+ P Sbjct 487 SKSDVWAFGVLLWEIATYG----MAPYPGVELSNVYG----------LLENGFRMDGPQG 532 Query 1140 CPCEVYHLMKNCWETEASFRPTFENL 1165 CP VY LM CW S RP F ++ Sbjct 533 CPPSVYRLMLQCWNWSPSDRPRFRDI 558 Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 81/300 (27%), Positives = 129/300 (43%), Gaps = 46/300 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 +D+ EI + LG G +VYEG + + +D PL Sbjct 306 LDRSEIIMHNKLGGGQYGDVYEGYWKRHDCTIAVKALKEDAMPL---------------- 349 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702 H+ F A++M + H +L + GVC ++TE++ +G L +LRR + Sbjct 350 -----HE----FLAEAAIMKDLHHKNLVRLLGVCTHEAPFYIITEFMCNGNLLEYLRRTD 400 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + +P + +A Q+AS +SYLE ++ +H ++ RN L++ + +K++D Sbjct 401 KSLLPPIILVQMASQIASGMSYLEARHFIHRDLAARNCLVSEHNI-------VKIAD--F 451 Query 763 GLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 GL +E+ I W APE L N+ S+ D W FG L EI G AP Sbjct 452 GLARFMKEDTYTAHAGAKFPIKWTAPEGL--AFNTFSSKSDVWAFGVLLWEIATYGMAPY 509 Query 816 QSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 S + R+ P+ P + L QC + P+ RP FR I +L L N Sbjct 510 PGVELSNVYGLLENGFRMDGPQGCPPSVYRLMLQCWNWSPSDRPRFRDIHFNLENLISSN 569 >sp|Q09YK0|MET_MUNMU Hepatocyte growth factor receptor OS=Muntiacus muntjak OX=9888 GN=MET PE=3 SV=1 Length=1382 Score = 147 bits (371), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 144/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T ND AVK+L S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLASK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ V + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1305 QPEYCPDALYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348 Score = 60.8 bits (146), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1184 GFGLQVAKGMEYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDVYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1295 VYLLQGRRLLQPEYCPDALYEVMLKCWHPKAELRPSFSELVSRISAI 1341 >sp|Q6EWH2|FYNA_DANRE Tyrosine-protein kinase fyna OS=Danio rerio OX=7955 GN=fyna PE=1 SV=2 Length=537 Score = 143 bits (360), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 91/277 (33%), Positives = 137/277 (49%), Gaps = 29/277 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ I+ LG G FG+V + ++ VAVK LK G + +E I++ L H Sbjct 271 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAVKTLKP--GTMSPESFLEEAQIMKKLRH 323 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013 + +++ E+ + +V EY+ GSL D+L + L L+ A Q+ GMAY Sbjct 324 DKLVQLYAVVS---EEPIYIVTEYMSKGSLLDFLKDGEGRGLKLPNLVDMAAQVAAGMAY 380 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + +YIHRDL + N+L+ + + KI DFGLA+ + + Y R+ P+ W APE Sbjct 381 IERMNYIHRDLRSANILVGDSLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 438 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +F SDVWSFG+ L EL+T + M + E +ERG R Sbjct 439 LYGRFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 484 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +P P CP ++ LM CW+ + RPTFE L L+ Sbjct 485 MPCPQDCPSSLHELMLQCWKRDPEERPTFEYLQAFLE 521 Score = 77.8 bits (190), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 67/230 (29%), Positives = 104/230 (45%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L Sbjct 295 KVAVKTLKPGTMSPE-SFLEEAQIMKKLRHDKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 352 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G S K Sbjct 353 FLKDGEGRGLKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GDSLVCK 405 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 406 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 463 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 P + E +R +R+P P CP L L QC +P +RP+F Sbjct 464 RVPYPGMNNREVLEQVERGYRMPCPQDCPSSLHELMLQCWKRDPEERPTF 513 >sp|Q2IBC0|MET_RHIFE Hepatocyte growth factor receptor OS=Rhinolophus ferrumequinum OX=59479 GN=MET PE=3 SV=1 Length=1381 Score = 147 bits (370), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T ND AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD + VK+ DFGLA+ V + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDENFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDHLYEVMLKCWHPKAEQRPSFAELVSRISAIFSAFIGE 1347 Score = 64.7 bits (156), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 56/227 (25%), Positives = 102/227 (45%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L + +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------NFTVKVADFGLARDVYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + QRPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDHLYEVMLKCWHPKAEQRPSFAELVSRISAI 1340 >sp|P04626|ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 OS=Homo sapiens OX=9606 GN=ERBB2 PE=1 SV=1 Length=1255 Score = 147 bits (370), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 89/278 (32%), Positives = 140/278 (50%), Gaps = 20/278 (7%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 + + L+K++ LG G FG V + P + VA+K L+ + P+ E + Sbjct 714 ILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYV 773 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQIC 1008 + + ++ + G C ++QLV + +P G L D++ R +G LL + QI Sbjct 774 MAGVGSPYVSRLLGICL---TSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIA 830 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +GM+YL +HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W Sbjct 831 KGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWM 889 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A E + +F + SDVWS+GVT++EL+T + + +LL Sbjct 890 ALESILRRRFTHQSDVWSYGVTVWELMT--------------FGAKPYDGIPAREIPDLL 935 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 E+GERLP+P C +VY +M CW ++ RP F L+ Sbjct 936 EKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELV 973 Score = 67.0 bits (162), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 86/369 (23%), Positives = 149/369 (40%), Gaps = 51/369 (14%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 +Q + + E+ ++ LG G VY+G +G E+ +P Sbjct 708 NQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDG-----------ENVKIP------- 749 Query 637 LRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +KVL + A + A +M+ V +++ + G+C+ +VT+ + +G L Sbjct 750 --VAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQLMPYGCL 806 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R RG + + Q+A +SYLE+ LVH ++ RN+L+ + + Sbjct 807 LDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVK-------SPNHV 859 Query 756 KLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 K++D GL L + E I W+A E + + D W +G T+ E+ Sbjct 860 KITD--FGLARLLDIDETEYHADGGKVPIKWMALESI--LRRRFTHQSDVWSYGVTVWEL 915 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRD 865 G P E ++ RLP+P + + +C + RP FR ++ + Sbjct 916 MTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSE 975 Query 866 LTRLQPHNLADVLTVNPD-SPASDPTVFHKRYLKKIRDLG------EGHFGKVSLYCYDP 918 +R+ V+ N D PAS R L + D+G E + +C DP Sbjct 976 FSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDP 1035 Query 919 TNDGTGEMV 927 G G MV Sbjct 1036 A-PGAGGMV 1043 >sp|P51451|BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo sapiens OX=9606 GN=BLK PE=1 SV=3 Length=505 Score = 142 bits (358), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 96/303 (32%), Positives = 146/303 (48%), Gaps = 32/303 (11%) Query 882 PDSP-ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH 940 P +P A D ++ L+ +R LG G FG+V + Y VA+K LK G Sbjct 225 PQNPWAQDEWEIPRQSLRLVRKLGSGQFGEVWMGYYK-----NNMKVAIKTLKE--GTMS 277 Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGL 997 + E ++++ L HE +++ + + +V EY+ G L D+L + L Sbjct 278 PEAFLGEANVMKALQHERLVRLYAVVTKE---PIYIVTEYMARGCLLDFLKTDEGSRLSL 334 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 +L+ + QI EGMAY+ + IHRDL A N+L+ KI DFGLA+ + Y Sbjct 335 PRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARII---DSEYTA 391 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 +E P+ W APE + F +DVWSFGV L E++T+ + Sbjct 392 QEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGR--------------VPYP 437 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYH-LMKNCWETEASFRPTFENLIPILKTVHEKY 1176 M+ + LERG R+PRPD CP E+Y ++ CW + RPTFE L +L+ + Sbjct 438 GMSNPEVIRNLERGYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEFLQSVLEDFYTAT 497 Query 1177 QGQ 1179 + Q Sbjct 498 ERQ 500 Score = 73.9 bits (180), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 60/226 (27%), Positives = 106/226 (47%), Gaps = 25/226 (11%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKM 712 AF A++M + H L ++ V + P I VTEY+ G L +L+ + G + + + Sbjct 280 AFLGEANVMKALQHERLVRLYAVVTKEPIYI-VTEYMARGCLLDFLKTDEGSRLSLPRLI 338 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 ++ Q+A ++Y+E N +H ++ NIL++ + K++D GL + E Sbjct 339 DMSAQIAEGMAYIERMNSIHRDLRAANILVSE-------ALCCKIAD--FGLARIIDSEY 389 Query 773 VER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + I W APE + G ++ D W FG L+E+ G P S E Sbjct 390 TAQEGAKFPIKWTAPEAIHFGVFTIKA--DVWSFGVLLMEVVTYGRVPYPGMSNPEVIRN 447 Query 827 YQRQHRLPEP-SCPQ--LATLTSQCLTYEPTQRPSF---RTILRDL 866 +R +R+P P +CP + ++C P +RP+F +++L D Sbjct 448 LERGYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEFLQSVLEDF 493 >sp|A1X150|MET_ECHTE Hepatocyte growth factor receptor OS=Echinops telfairi OX=9371 GN=MET PE=3 SV=1 Length=1380 Score = 147 bits (370), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 144/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T ND AVK+L S + E I++ H ++ Sbjct 1083 IGRGHFGCV----YHGTLLDNDDRKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1138 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ HS + L+ F Q+ +GM YL ++ Sbjct 1139 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHSPTVKDLIGFGLQVAKGMKYLASK 1197 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1198 KFVHRDLAARNCMLDGKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1256 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1257 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1302 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1303 QPEYCPDPLYEVMLKCWHPKAEMRPSFTELVSRISAIFSTFIGE 1346 Score = 62.0 bits (149), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 56/227 (25%), Positives = 102/227 (45%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1123 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HSPTVKDLI 1181 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +G +K++D G+ +E Sbjct 1182 GFGLQVAKGMKYLASKKFVHRDLAARNCML------DGKFT-VKVADFGLARDMYDKEYY 1234 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1235 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1292 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1293 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFTELVSRISAI 1339 >sp|Q769I5|MET_BOVIN Hepatocyte growth factor receptor OS=Bos taurus OX=9913 GN=MET PE=2 SV=1 Length=1384 Score = 147 bits (370), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 144/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T ND AVK+L S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLASK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ V + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISVIFSTFIGE 1348 Score = 60.8 bits (146), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1184 GFGLQVAKGMEYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDVYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISVI 1341 >sp|F1RDG9|FYNB_DANRE Tyrosine-protein kinase fynb OS=Danio rerio OX=7955 GN=fynb PE=2 SV=1 Length=544 Score = 142 bits (359), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 91/277 (33%), Positives = 138/277 (50%), Gaps = 29/277 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ I+ LG G FG+V + ++ VA+K LK G + +E I++ L H Sbjct 278 LQLIKRLGNGQFGEVWMGTWNGNTK-----VAIKTLKP--GTMSPESFLEEAQIMKKLRH 330 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAY 1013 + +++ E+ + +V EY+ GSL D+L ++ L L+ A Q+ GMAY Sbjct 331 DKLVQLYAVVS---EEPIYIVTEYMGKGSLLDFLKDGEGRALKLPNLVDMAAQVAGGMAY 387 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + +YIHRDL + N+L+ + + KI DFGLA+ + + Y R+ P+ W APE Sbjct 388 IERMNYIHRDLRSANILVGDSLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 445 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 KF SDVWSFG+ L EL+T + M + E +ERG R Sbjct 446 LYGKFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 491 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + P CP ++ LM CW+ +A RPTFE L L+ Sbjct 492 MQCPQDCPSSLHELMVQCWKKDAEERPTFEYLQAFLE 528 Score = 73.2 bits (178), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 65/230 (28%), Positives = 101/230 (44%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P +F E A +M ++ H L ++ V P I VTEY+ G L Sbjct 302 KVAIKTLKPGTMSPE-SFLEEAQIMKKLRHDKLVQLYAVVSEEPIYI-VTEYMGKGSLLD 359 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G +V +A Q+A ++Y+E N +H ++ NIL+ G S K Sbjct 360 FLKDGEGRALKLPNLVDMAAQVAGGMAYIERMNYIHRDLRSANILV-------GDSLVCK 412 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 413 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGKFTIKS--DVWSFGILLTELVTKG 470 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 P + E +R +R+ P CP L L QC + +RP+F Sbjct 471 RVPYPGMNNREVLEQVERGYRMQCPQDCPSSLHELMVQCWKKDAEERPTF 520 >sp|P70424|ERBB2_MOUSE Receptor tyrosine-protein kinase erbB-2 OS=Mus musculus OX=10090 GN=Erbb2 PE=1 SV=3 Length=1256 Score = 146 bits (369), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 89/278 (32%), Positives = 140/278 (50%), Gaps = 20/278 (7%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 + + L+K++ LG G FG V + P + VA+K L+ + P+ E + Sbjct 715 ILKETELRKLKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYV 774 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQIC 1008 + + ++ + G C ++QLV + +P G L D++ H +G LL + QI Sbjct 775 MAGVGSPYVSRLLGICL---TSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIA 831 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +GM+YL +HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W Sbjct 832 KGMSYLEEVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWM 890 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A E + +F + SDVWS+GVT++EL+T + + +LL Sbjct 891 ALESILRRRFTHQSDVWSYGVTVWELMT--------------FGAKPYDGIPAREIPDLL 936 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 E+GERLP+P C +VY +M CW ++ RP F L+ Sbjct 937 EKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELV 974 Score = 65.9 bits (159), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 79/342 (23%), Positives = 141/342 (41%), Gaps = 46/342 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 +Q + + E+ +L LG G VY+G +G E+ +P Sbjct 709 NQAQMRILKETELRKLKVLGSGAFGTVYKGIWIPDG-----------ENVKIP------- 750 Query 637 LRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +KVL + A + A +M+ V +++ + G+C+ +VT+ + +G L Sbjct 751 --VAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQLMPYGCL 807 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R RG + + Q+A +SYLE LVH ++ RN+L+ + + Sbjct 808 LDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVRLVHRDLAARNVLVK-------SPNHV 860 Query 756 KLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 K++D GL L + E I W+A E + + D W +G T+ E+ Sbjct 861 KITD--FGLARLLDIDETEYHADGGKVPIKWMALESI--LRRRFTHQSDVWSYGVTVWEL 916 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRD 865 G P E ++ RLP+P + + +C + RP FR ++ + Sbjct 917 MTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSE 976 Query 866 LTRLQPHNLADVLTVNPDSPASDP--TVFHKRYLKKIRDLGE 905 +R+ V+ N D S P + F++ L+ D+GE Sbjct 977 FSRMARDPQRFVVIQNEDLGPSSPMDSTFYRSLLED-DDMGE 1017 >sp|P63185|SRC_RSVSE Tyrosine-protein kinase transforming protein Src OS=Rous sarcoma virus subgroup E (strain Schmidt-Ruppin) OX=270623 GN=V-SRC PE=1 SV=3 Length=526 Score = 142 bits (358), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 98/301 (33%), Positives = 151/301 (50%), Gaps = 34/301 (11%) Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 H L +V T P + A D + L+ LG+G FG+V + ++ T VA Sbjct 239 HRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTT-----RVA 293 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK G + QE +++ L H+ +++ E+ + +V+EY+ GSL D Sbjct 294 IKTLKP--GTMSPEAFLQEAQVMKKLRHKKLVQLYAVVS---EEPIYIVIEYMSKGSLLD 348 Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 349 FL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + G+ G+ + + +ERG R+P P +CP ++ LM CW + RPTFE Sbjct 461 ----VPYPGMGNGE-----VLDRVERGYRMPCPPECPESLHDLMSQCWRRDPEERPTFEY 511 Query 1165 L 1165 L Sbjct 512 L 512 Score = 83.2 bits (204), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 70/237 (30%), Positives = 109/237 (46%), Gaps = 19/237 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I++ EY+ G L Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHKKLVQLYAVVSEEPIYIVI-EYMSKGSLLD 348 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866 P E +R +R+P P CP+ L L SQC +P +RP+F + L Sbjct 460 RVPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMSQCWRRDPEERPTFEYLQAQL 516 >sp|P29320|EPHA3_HUMAN Ephrin type-A receptor 3 OS=Homo sapiens OX=9606 GN=EPHA3 PE=1 SV=2 Length=983 Score = 146 bits (368), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 87/270 (32%), Positives = 141/270 (52%), Gaps = 21/270 (8%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG+V S P+ VA+K LK + R + E I+ H +II+ Sbjct 627 VGAGEFGEVCSGRLKLPSKKEIS--VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIR 684 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHY 1019 +G K + +V EY+ GSL +L +H + QL+ + I GM YL Y Sbjct 685 LEGVVTKS--KPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGY 742 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W +PE + KF Sbjct 743 VHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFT 802 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 ASDVWS+G+ L+E++++ + P +M+ + + ++ G RLP P Sbjct 803 SASDVWSYGIVLWEVMSY---GERP-----------YWEMSNQDVIKAVDEGYRLPPPMD 848 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 CP +Y LM +CW+ + + RP FE ++ IL Sbjct 849 CPAALYQLMLDCWQKDRNNRPKFEQIVSIL 878 Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 68/245 (28%), Positives = 110/245 (45%), Gaps = 19/245 (8%) Query 635 QELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +E+ V +K L + + F AS+M Q H ++ + GV + ++VTEY+E+G Sbjct 646 KEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENG 705 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 LD +LR+ + + + + +AS + YL + VH ++ RNIL+ ++ Sbjct 706 SLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILI-------NSNL 758 Query 754 FIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLE 806 K+SD G+ E R +IP W +PE + ++A D W +G L E Sbjct 759 VCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAI--AYRKFTSASDVWSYGIVLWE 816 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILR 864 + GE P S + +RLP P CP L L C + RP F I+ Sbjct 817 VMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVS 876 Query 865 DLTRL 869 L +L Sbjct 877 ILDKL 881 >sp|P00524|SRC_RSVSA Tyrosine-protein kinase transforming protein Src OS=Rous sarcoma virus subgroup A (strain Schmidt-Ruppin) OX=269446 GN=V-SRC PE=1 SV=6 Length=526 Score = 142 bits (358), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 99/301 (33%), Positives = 151/301 (50%), Gaps = 34/301 (11%) Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 H L +V T P + A D + L+ LG+G FG+V + ++ T VA Sbjct 239 HRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTT-----RVA 293 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL D Sbjct 294 IKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS---EEPIYIVIEYMSKGSLLD 348 Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 349 FL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + G+ G+ + + +ERG R+P P +CP ++ LM CW + RPTFE Sbjct 461 ----VPYPGMGNGE-----VLDRVERGYRMPCPPECPESLHDLMCQCWRRDPEERPTFEY 511 Query 1165 L 1165 L Sbjct 512 L 512 Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 69/237 (29%), Positives = 108/237 (46%), Gaps = 19/237 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I++ EY+ G L Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVI-EYMSKGSLLD 348 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866 P E +R +R+P P CP+ L L QC +P +RP+F + L Sbjct 460 RVPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMCQCWRRDPEERPTFEYLQAQL 516 >sp|Q09YI9|MET_SHEEP Hepatocyte growth factor receptor OS=Ovis aries OX=9940 GN=MET PE=3 SV=1 Length=1384 Score = 146 bits (369), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 144/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T ND AVK+L S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLASK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS--PVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ V + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRIAAIFSAFIGE 1348 Score = 60.8 bits (146), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 99/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1184 GFGLQVAKGMEYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDVYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ + + Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRIAAI 1341 >sp|Q00PJ8|MET_ATEAB Hepatocyte growth factor receptor OS=Atelerix albiventris OX=9368 GN=MET PE=3 SV=1 Length=1382 Score = 146 bits (369), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 96/284 (34%), Positives = 145/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T ND AVK+L S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD + VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDENFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348 Score = 61.2 bits (147), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 101/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L + +K++D G+ +E Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------NFTVKVADFGLARDMYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1341 >sp|Q8AXY6|MUSK_CHICK Muscle, skeletal receptor tyrosine protein kinase OS=Gallus gallus OX=9031 GN=MUSK PE=2 SV=1 Length=947 Score = 145 bits (367), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 93/313 (30%), Positives = 156/313 (50%), Gaps = 51/313 (16%) Query 892 FHKRYLKKIRDLGEGHFGKV------SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 + + ++ +RD+GEG FG+V L Y+P MVAVK LK + ++ ++ Sbjct 650 YPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFT-----MVAVKMLKEEASADMQADFQ 704 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ-- 999 +E ++ + +I+K G C K + L+ EY+ G L +YL PR+ L Q Sbjct 705 REAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEYLRDRSPRNLCSLVQGG 762 Query 1000 -----------------LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 L A+Q+ GMAYL + ++HRDLA RN L+ + +VKI DF Sbjct 763 LEARACLLNPLALCCTSQLCIAKQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADF 822 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 GL++ + +YY+ E+ P+ W PE + ++ SDVW++GV L+E+ ++ Sbjct 823 GLSRNMYSA-DYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSY----- 876 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 G+A ++ + G L PD CP E+Y+LM+ CW + RP+F Sbjct 877 ----GMQPYYGMAHEEVIY-----YVRDGNILSCPDNCPLELYNLMRLCWSKLPADRPSF 927 Query 1163 ENLIPILKTVHEK 1175 ++ IL+ ++E+ Sbjct 928 ASIHRILERMYER 940 Score = 77.4 bits (189), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 69/268 (26%), Positives = 120/268 (45%), Gaps = 39/268 (15%) Query 639 VVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V +K+L + + D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+ Sbjct 686 VAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNE 745 Query 698 WLR-----------------RERGHVPMAW----KMVVAQQLASALSYLENKNLVHGNVC 736 +LR R P+A ++ +A+Q+A+ ++YL + VH ++ Sbjct 746 YLRDRSPRNLCSLVQGGLEARACLLNPLALCCTSQLCIAKQVAAGMAYLSERKFVHRDLA 805 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANS 790 RN L+ G + +K++D G+ S E I W+ PE + N Sbjct 806 TRNCLV-------GENMVVKIADFGLSRNMYSADYYKANENDAIPIRWMPPESI--FYNR 856 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQC 848 +T D W +G L EI G P + E ++ + + L P +CP +L L C Sbjct 857 YTTESDVWAYGVVLWEIFSYGMQPYYGMAHEEVIYYVRDGNILSCPDNCPLELYNLMRLC 916 Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLAD 876 + P RPSF +I R L R+ +A Sbjct 917 WSKLPADRPSFASIHRILERMYERAVAS 944 >sp|O08680|EPHA3_RAT Ephrin type-A receptor 3 OS=Rattus norvegicus OX=10116 GN=Epha3 PE=2 SV=1 Length=984 Score = 145 bits (367), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 88/270 (33%), Positives = 140/270 (52%), Gaps = 21/270 (8%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG+V S P+ VA+K LK + R + E I+ H +II+ Sbjct 628 VGAGEFGEVCSGRLKLPSKKEIS--VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIR 685 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHY 1019 +G K + +V EY+ GSL +L +H + QL+ + I GM YL Y Sbjct 686 LEGVVTKS--KPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGY 743 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDLAARN+L++++ + K+ DFGL++ + + E G PV W +PE KF Sbjct 744 VHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPVRWTSPEATAYRKFT 803 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 ASDVWS+G+ L+E++++ + P +M+ + + ++ G RLP P Sbjct 804 SASDVWSYGIVLWEVMSY---GERP-----------YWEMSNQDVIKAVDEGYRLPLPMD 849 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 CP +Y LM +CW+ + + RP FE ++ IL Sbjct 850 CPAALYQLMLDCWQKDRNNRPKFEQIVSIL 879 Score = 84.7 bits (208), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 68/245 (28%), Positives = 109/245 (44%), Gaps = 19/245 (8%) Query 635 QELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +E+ V +K L + + F AS+M Q H ++ + GV + ++VTEY+E+G Sbjct 647 KEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENG 706 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 LD +LR+ + + + + +AS + YL + VH ++ RNIL+ ++ Sbjct 707 SLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILI-------NSNL 759 Query 754 FIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLE 806 K+SD G+ E R +IP W +PE ++A D W +G L E Sbjct 760 VCKVSDFGLSRVLEDDPEAAYTTRGGKIPVRWTSPEAT--AYRKFTSASDVWSYGIVLWE 817 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILR 864 + GE P S + +RLP P CP L L C + RP F I+ Sbjct 818 VMSYGERPYWEMSNQDVIKAVDEGYRLPLPMDCPAALYQLMLDCWQKDRNNRPKFEQIVS 877 Query 865 DLTRL 869 L +L Sbjct 878 ILDKL 882 >sp|Q2QLE0|MET_PIG Hepatocyte growth factor receptor OS=Sus scrofa OX=9823 GN=MET PE=2 SV=1 Length=1381 Score = 146 bits (368), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 143/284 (50%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T ND AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ V + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGE 1347 Score = 60.5 bits (145), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 99/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDVYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAI 1340 >sp|Q9WUD9|SRC_RAT Proto-oncogene tyrosine-protein kinase Src OS=Rattus norvegicus OX=10116 GN=Src PE=1 SV=4 Length=536 Score = 142 bits (357), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 90/271 (33%), Positives = 136/271 (50%), Gaps = 29/271 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++ Sbjct 276 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQL 328 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHY 1019 E+ + +V EY+ GSL D+L + + L QL+ + QI GMAY+ +Y Sbjct 329 YAVV---SEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNY 385 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F Sbjct 386 VHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFT 443 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SDVWSFG+ L EL T + M + + +ERG R+P P + Sbjct 444 IKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPPE 489 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 CP ++ LM CW E RPTFE L L+ Sbjct 490 CPESLHDLMCQCWRKEPEERPTFEYLQAFLE 520 Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L Sbjct 294 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMNKGSLLD 351 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V ++ Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 352 FLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 404 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 405 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 462 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859 P E +R +R+P P CP+ L L QC EP +RP+F Sbjct 463 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTF 512 >sp|P05480|SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src OS=Mus musculus OX=10090 GN=Src PE=1 SV=5 Length=535 Score = 142 bits (357), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 90/271 (33%), Positives = 136/271 (50%), Gaps = 29/271 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++ Sbjct 275 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQL 327 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHY 1019 E+ + +V EY+ GSL D+L + + L QL+ + QI GMAY+ +Y Sbjct 328 YAVV---SEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNY 384 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F Sbjct 385 VHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFT 442 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SDVWSFG+ L EL T + M + + +ERG R+P P + Sbjct 443 IKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPPE 488 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 CP ++ LM CW E RPTFE L L+ Sbjct 489 CPESLHDLMCQCWRKEPEERPTFEYLQAFLE 519 Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L Sbjct 293 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMNKGSLLD 350 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V ++ Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 351 FLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 403 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 404 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 461 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859 P E +R +R+P P CP+ L L QC EP +RP+F Sbjct 462 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTF 511 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens OX=9606 GN=ABL2 PE=1 SV=1 Length=1182 Score = 145 bits (367), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 94/287 (33%), Positives = 145/287 (51%), Gaps = 27/287 (9%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 TV SP D + + LG G +G+V + + + VAVK LK D Sbjct 270 TVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYS----LTVAVKTLKEDT-- 323 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSI 995 + +E +++ + H ++++ G C E +V EY+P G+L DYL R + Sbjct 324 MEVEEFLKEAAVMKEIKHPNLVQLLGVC--TLEPPFYIVTEYMPYGNLLDYLRECNREEV 381 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 LL A QI M YL +++IHRDLAARN L+ + +VK+ DFGL++ + + Y Sbjct 382 TAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDTY 439 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 P+ W APE L F SDVW+FGV L+E+ T+ S P ++L Sbjct 440 TAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMS----PYPGIDLS--- 492 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 ++ +LLE+G R+ +P+ CP +VY LM+ CW+ + RP+F Sbjct 493 -------QVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSF 532 Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 70/231 (30%), Positives = 109/231 (47%), Gaps = 18/231 (8%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 L V +K L ++ F + A++M ++ H +L + GVC P +VTEY+ +G L Sbjct 312 LTVAVKTLKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLL 370 Query 697 VWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +LR R V + +A Q++SA+ YLE KN +H ++ RN L+ G + + Sbjct 371 DYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV-------GENHVV 423 Query 756 KLSDPGVG---LGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ G + P W APE L N+ S D W FG L EI Sbjct 424 KVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESL--AYNTFSIKSDVWAFGVLLWEIATY 481 Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859 G +P S+ ++ +R+ PE P++ L C + P RPSF Sbjct 482 GMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSF 532 >sp|P54756|EPHA5_HUMAN Ephrin type-A receptor 5 OS=Homo sapiens OX=9606 GN=EPHA5 PE=1 SV=3 Length=1037 Score = 145 bits (366), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 89/273 (33%), Positives = 142/273 (52%), Gaps = 23/273 (8%) Query 901 RDLGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 R +G G FG+V C G E+ VA+K LK + R + E I+ H + Sbjct 679 RVIGAGEFGEV---CSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPN 735 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHA 1016 II +G K + +V EY+ GSL +L ++ + QL+ + I GM YL Sbjct 736 IIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSD 793 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W APE + Sbjct 794 MGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFR 853 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 KF ASDVWS+G+ ++E++++ + P +MT + + +E G RLP Sbjct 854 KFTSASDVWSYGIVMWEVVSY---GERP-----------YWEMTNQDVIKAVEEGYRLPS 899 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P CP +Y LM +CW+ E + RP F+ ++ +L Sbjct 900 PMDCPAALYQLMLDCWQKERNSRPKFDEIVNML 932 Score = 90.1 bits (222), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 79/286 (28%), Positives = 129/286 (45%), Gaps = 33/286 (12%) Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSH 667 RV G+G E G++ +PG+ +EL V +K L + + F AS+M Q H Sbjct 679 RVIGAG--EFGEVCSGRLKLPGK---RELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDH 733 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 ++ + GV + ++VTEY+E+G LD +L++ G + + + + +++ + YL + Sbjct 734 PNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSD 793 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIP--WLA 780 VH ++ RNIL+ ++ K+SD G+ E R +IP W A Sbjct 794 MGYVHRDLAARNILI-------NSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTA 846 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP 839 PE + ++A D W +G + E+ GE P + + + +RLP P CP Sbjct 847 PEAI--AFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCP 904 Query 840 -QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884 L L C E RP F I+ N+ D L NP S Sbjct 905 AALYQLMLDCWQKERNSRPKFDEIV---------NMLDKLIRNPSS 941 >sp|P54755|EPHA5_CHICK Ephrin type-A receptor 5 OS=Gallus gallus OX=9031 GN=EPHA5 PE=2 SV=1 Length=1013 Score = 145 bits (366), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 88/273 (32%), Positives = 141/273 (52%), Gaps = 23/273 (8%) Query 901 RDLGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 R +G G FG+V C G E VA+K LK + R + E I+ H + Sbjct 655 RVIGAGEFGEV---CSGRLKLQGKREFPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPN 711 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHA 1016 II +G K + +V EY+ GSL +L ++ + QL+ + I GM YL Sbjct 712 IIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIASGMKYLSD 769 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W APE + Sbjct 770 MGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFR 829 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 KF ASDVWS+G+ ++E++++ + P +MT + + +E G RLP Sbjct 830 KFTSASDVWSYGIVMWEVMSY---GERP-----------YWEMTNQDVIKAVEEGYRLPS 875 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P CP +Y LM +CW+ + + RP F+ ++ +L Sbjct 876 PMDCPAALYQLMLDCWQKDRNSRPKFDEIVSML 908 Score = 90.5 bits (223), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 84/317 (26%), Positives = 135/317 (43%), Gaps = 44/317 (14%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 IT +G G V GRL+++G +E V +K L + Sbjct 651 ITIERVIGAGEFGEVCSGRLKLQGK---------------------REFPVAIKTLKVGY 689 Query 649 HDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 + F AS+M Q H ++ + GV + ++VTEY+E+G LD +L++ G Sbjct 690 TEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFT 749 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 + + + + +AS + YL + VH ++ RNIL+ ++ K+SD G+ Sbjct 750 VIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILI-------NSNLVCKVSDFGLSRVLE 802 Query 768 SREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 E R +IP W APE + ++A D W +G + E+ GE P + Sbjct 803 DDPEAAYTTRGGKIPIRWTAPEAI--AFRKFTSASDVWSYGIVMWEVMSYGERPYWEMTN 860 Query 821 SEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLAD 876 + + +RLP P CP L L C + RP F I+ L +L P +L Sbjct 861 QDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVSMLDKLIRNPSSLKT 920 Query 877 VLTVNPDSPASDPTVFH 893 + VN S S+ V H Sbjct 921 L--VNASSRVSNLLVEH 935 >sp|P42682|TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus musculus OX=10090 GN=Txk PE=1 SV=1 Length=527 Score = 141 bits (356), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 98/292 (34%), Positives = 140/292 (48%), Gaps = 47/292 (16%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-----VAVKALKADCGPQHRSGWKQEIDIL 951 L ++++G G FG V L GE VA+KA+ G + +E ++ Sbjct 271 LAFVKEIGSGQFGVVHL----------GEWRAHIPVAIKAINE--GSMSEEDFIEEAKVM 318 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICE 1009 L H +++ G C Q K L +V E++ G L DYL L + LL + Q ICE Sbjct 319 MKLSHSRLVQLYGVCIQQ--KPLYIVTEFMENGCLLDYLRERKGQLQKALLLSMCQDICE 376 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 GMAYL YIHRDLAARN L+ + +VKI DFG+A+ V + Y PV W Sbjct 377 GMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARYVLDDE--YISSSGAKFPVKWCP 434 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM-----TVLRL 1124 PE K+ SDVWSFGV ++E+ T +G+M + L++ Sbjct 435 PEVFHFNKYSSKSDVWSFGVLMWEVFT-------------------EGKMPFENKSNLQV 475 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 E + +G RL RP P +Y +M +CW RPTF L+ +L + E + Sbjct 476 VEAISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVLTEIAETW 527 Score = 89.0 bits (219), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 58/222 (26%), Positives = 105/222 (47%), Gaps = 16/222 (7%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F E A +M ++SH+ L ++GVC++ +VTE++E+G L +LR +G + A + + Sbjct 311 FIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRERKGQLQKALLLSM 370 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 Q + ++YLE +H ++ RN L++ ++ +K+SD G+ L E Sbjct 371 CQDICEGMAYLERSCYIHRDLAARNCLVS-------SACVVKISDFGMARYVLDDEYISS 423 Query 775 R-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 + W PE N S+ D W FG + E+ +G+ P +++S + + Sbjct 424 SGAKFPVKWCPPEVF--HFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISQ 481 Query 830 QHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869 RL P + + C P RP+F +L+ LT + Sbjct 482 GFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVLTEI 523 >sp|P14084|SRC_AVISS Tyrosine-protein kinase transforming protein Src OS=Avian sarcoma virus (strain S1) OX=11881 GN=V-SRC PE=3 SV=3 Length=568 Score = 142 bits (358), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 91/272 (33%), Positives = 137/272 (50%), Gaps = 31/272 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++ Sbjct 273 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVRL 325 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLHAQH 1018 E+ + +V EY+ GSL D+L + +G L QL+ A QI GMAY+ + Sbjct 326 YAVV---SEEPIYIVTEYMSKGSLLDFL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMN 381 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 Y+HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F Sbjct 382 YVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRF 439 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SDVWSFG+ L EL T + M + + +ERG R+P P Sbjct 440 TIKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPP 485 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +CP ++ LM CW + RPTFE L L+ Sbjct 486 ECPESLHDLMCQCWRKDPEERPTFEYLQAFLE 517 Score = 82.0 bits (201), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVRLYAVVSEEPIYI-VTEYMSKGSLLD 348 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859 P E +R +R+P P CP+ L L QC +P +RP+F Sbjct 460 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTF 509 >sp|P00526|SRC_RSVP Tyrosine-protein kinase transforming protein Src OS=Rous sarcoma virus subgroup C (strain Prague) OX=11888 GN=V-SRC PE=1 SV=3 Length=526 Score = 141 bits (356), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 98/301 (33%), Positives = 149/301 (50%), Gaps = 34/301 (11%) Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 H LA+V T P + A D + L+ LG+G FG+V + ++ T VA Sbjct 239 HRLANVCPTSKPQTQGLAKDAWEIPRESLRLEAKLGQGCFGEVWMGTWNDTT-----RVA 293 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL D Sbjct 294 IKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVIEYMSKGSLLD 348 Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 349 FL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW + RPTF+ Sbjct 461 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFKY 511 Query 1165 L 1165 L Sbjct 512 L 512 Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 69/237 (29%), Positives = 109/237 (46%), Gaps = 19/237 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I++ EY+ G L Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVI-EYMSKGSLLD 348 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866 P E +R +R+P P CP+ L L QC +P +RP+F+ + L Sbjct 460 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFKYLQAQL 516 >sp|P27447|YES_XIPHE Tyrosine-protein kinase Yes OS=Xiphophorus hellerii OX=8084 GN=yes PE=2 SV=3 Length=544 Score = 141 bits (356), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 88/271 (32%), Positives = 138/271 (51%), Gaps = 29/271 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+V + ++ T VA+K LK G + +E I++ L H+ ++ Sbjct 284 LGQGCFGEVWMGTWNGTTK-----VAIKTLKP--GTMSPEAFLEEAQIMKKLRHDKLVPL 336 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHY 1019 E+ + +V E++ GSL D+L + L QL+ A QI +GMA++ +Y Sbjct 337 YAVVS---EEPIYIVTEFMGKGSLLDFLKEGDGKHLKLPQLVDMASQIADGMAFIERMNY 393 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRDL A N+L+ ++ + KI DFGLA+ + + Y R+ P+ W APE +F Sbjct 394 IHRDLRAANILVADNLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFT 451 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SDVWSFG+ L EL+T + M + E ++RG R+P P Sbjct 452 IKSDVWSFGILLTELVTKGR--------------VPYPGMVNREVLEQVDRGYRMPCPQG 497 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 CP ++ +M+ CW+ E RPTFE + L+ Sbjct 498 CPESLHEMMRQCWKKEPDERPTFEYIQSFLE 528 Score = 78.6 bits (192), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 66/233 (28%), Positives = 105/233 (45%), Gaps = 19/233 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P AF E A +M ++ H L ++ V P I VTE++ G L Sbjct 302 KVAIKTLKPGTMSPE-AFLEEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEFMGKGSLLD 359 Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G H+ + + +A Q+A ++++E N +H ++ NIL+A + K Sbjct 360 FLKEGDGKHLKLPQLVDMASQIADGMAFIERMNYIHRDLRAANILVA-------DNLVCK 412 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 413 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 470 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 P E R +R+P P CP+ L + QC EP +RP+F I Sbjct 471 RVPYPGMVNREVLEQVDRGYRMPCPQGCPESLHEMMRQCWKKEPDERPTFEYI 523 >sp|P00525|SRC_AVISR Tyrosine-protein kinase transforming protein Src OS=Avian sarcoma virus (strain rASV1441) OX=11894 GN=V-SRC PE=1 SV=3 Length=526 Score = 141 bits (356), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 99/301 (33%), Positives = 150/301 (50%), Gaps = 34/301 (11%) Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 H L +V T P + A D + L+ LG+G FG+V + ++ T VA Sbjct 239 HRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTT-----RVA 293 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK G + QE +++ L HE +++ E+ + +V EY+ GSL D Sbjct 294 IKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS---EEPIYIVTEYMSKGSLLD 348 Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 349 FL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + G+ G+ + + +ERG R+P P +CP ++ LM CW + RPTFE Sbjct 461 ----VPYPGMGNGE-----VLDRVERGYRMPCPPECPESLHDLMCQCWRRDPEERPTFEY 511 Query 1165 L 1165 L Sbjct 512 L 512 Score = 82.8 bits (203), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 348 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859 P E +R +R+P P CP+ L L QC +P +RP+F Sbjct 460 RVPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMCQCWRRDPEERPTF 509 >sp|Q8MY85|FGFR2_DUGJA Fibroblast growth factor receptor 2 OS=Dugesia japonica OX=6161 GN=FGFR2 PE=2 SV=1 Length=887 Score = 144 bits (364), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 120/365 (33%), Positives = 170/365 (47%), Gaps = 54/365 (15%) Query 837 SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896 S + LTS LT E TQRP IL++ N +L P++ +F + Sbjct 539 SNTETNKLTSNSLTVE-TQRPQL--ILQN-----DANTKYIL------PSNIGWIFSRDS 584 Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTL- 954 L +GEG FG V ++ + + VA+K L G Q QE+++++ + Sbjct 585 LIIGSKIGEGAFGIVYSALVKSFSENSASVEVAIKTLHTSFGDQDVINLIQELEMMKIIG 644 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------PRHSIGLA----- 998 H HII G C D G +V+E G+LRD+L ++S GL Sbjct 645 RHRHIISLYGACIDNGHP--YMVIELAKHGNLRDFLRAQRSQSKVGEIQNSGGLVTRLTV 702 Query 999 -QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 L F+ +I EGM YL ++ IHRDLAARNVL+D +KI DFGL + V YYR Sbjct 703 TDFLRFSIEIAEGMEYLSSRKIIHRDLAARNVLVDQYVEMKIADFGLTRIV---ENYYRK 759 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQ 1116 DG P+ W APECL + + SDVWS+G+ L+E+ T Q+P PT ++ G+ Q Sbjct 760 TTDGRLPIKWMAPECLLDRVYTVKSDVWSYGIVLWEIFTM---GQTPYPT--IQSDGMHQ 814 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 L G R +P E+Y LM W + R TF +I L + Sbjct 815 A----------LRNGIRNEKPALASDEMYRLMLTIWNDDPLERHTFSEIIDKLTHIQLSN 864 Query 1177 QGQAP 1181 G +P Sbjct 865 GGSSP 869 Score = 64.3 bits (155), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 54/231 (23%), Positives = 101/231 (44%), Gaps = 36/231 (16%) Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-----GHVPMAWKMVV------- 714 H H+ ++G C+ MV E +HG L +LR +R G + + +V Sbjct 646 HRHIISLYGACIDNGHPYMVIELAKHGNLRDFLRAQRSQSKVGEIQNSGGLVTRLTVTDF 705 Query 715 ---AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--- 768 + ++A + YL ++ ++H ++ RN+L+ + ++++ GL + Sbjct 706 LRFSIEIAEGMEYLSSRKIIHRDLAARNVLVDQ---------YVEMKIADFGLTRIVENY 756 Query 769 -REERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP---LQSRSPSE 822 R+ R+P W+APECL ++ + D W +G L EI G+ P +QS + Sbjct 757 YRKTTDGRLPIKWMAPECLLDRVYTVKS--DVWSYGIVLWEIFTMGQTPYPTIQSDGMHQ 814 Query 823 KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 R + P + ++ L +P +R +F I+ LT +Q N Sbjct 815 ALRNGIRNEK-PALASDEMYRLMLTIWNDDPLERHTFSEIIDKLTHIQLSN 864 >sp|P13115|SRC1_XENLA Tyrosine-protein kinase Src-1 OS=Xenopus laevis OX=8355 GN=src-a PE=2 SV=4 Length=532 Score = 141 bits (356), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 91/272 (33%), Positives = 136/272 (50%), Gaps = 31/272 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++ Sbjct 272 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQL 324 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLHAQH 1018 E+ + +V EY+ GSL D+L + +G L QL+ A QI GMAY+ + Sbjct 325 YAVVS---EEPIYIVTEYISKGSLLDFL-KGEMGRYLRLPQLVDMAAQIASGMAYVERMN 380 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 Y+HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F Sbjct 381 YVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRF 438 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SDVWSFG+ L EL T + M + + +ERG R+P P Sbjct 439 TIKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPP 484 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 CP ++ LM CW + RPTFE L L+ Sbjct 485 DCPESLHDLMFQCWRKDPEERPTFEYLQAFLE 516 Score = 83.2 bits (204), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L Sbjct 290 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYISKGSLLD 347 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 348 FLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 400 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 401 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 458 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859 P E +R +R+P P CP+ L L QC +P +RP+F Sbjct 459 RVPYPGMVNREVLDQVERGYRMPCPPDCPESLHDLMFQCWRKDPEERPTF 508 >sp|Q2QLA9|MET_HORSE Hepatocyte growth factor receptor OS=Equus caballus OX=9796 GN=MET PE=3 SV=1 Length=1381 Score = 145 bits (366), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 96/284 (34%), Positives = 144/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T ND AVK+L S + E I++ H ++ Sbjct 1084 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1140 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1257 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1258 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1303 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 QPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1347 Score = 60.8 bits (146), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1124 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1182 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1235 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1236 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1293 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1294 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1340 >sp|Q07E24|MET_MUSPF Hepatocyte growth factor receptor OS=Mustela putorius furo OX=9669 GN=MET PE=3 SV=1 Length=1382 Score = 145 bits (366), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 96/284 (34%), Positives = 144/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T ND AVK+L S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348 Score = 60.8 bits (146), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1341 >sp|Q8MY86|FGFR1_DUGJA Fibroblast growth factor receptor 1 OS=Dugesia japonica OX=6161 GN=FGFR1 PE=2 SV=1 Length=854 Score = 144 bits (364), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 94/295 (32%), Positives = 150/295 (51%), Gaps = 37/295 (13%) Query 901 RDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEH 958 + LGEG FG V D N VAVK ++ D + + +E++I++ + H + Sbjct 555 KKLGEGAFGMVYEGIANDIGNRSNPIKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPN 614 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------------SIGLAQLLLFAQQ 1006 +I+ G C +G L++++E P G+LRD++ + + L ++ Q Sbjct 615 VIQLLGLCTQKG--PLRVIVELAPYGNLRDFVRAKNKKYSKSKKIIGNFTSSILCTYSLQ 672 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I GM YL ++ +HRDL+ARN+L+ +KI DFGL + V YYR + DG PV Sbjct 673 IARGMTYLASRSVVHRDLSARNILVGEHFEMKIADFGLTRIVDY---YYRKKTDGILPVK 729 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLELIGIAQGQMTVLRL 1124 W APE L E K+ SDVWS+G+ L+E+ T DS S P K ++LI Sbjct 730 WMAPEALLEKKYTTKSDVWSYGILLWEIFTLGDSPYSAILPEKVVDLI------------ 777 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +G + P+P+ E+Y LM++CW + RP F ++ IL + ++ + Sbjct 778 ----RKGFQNPKPELANFEIYRLMQHCWSLSSENRPNFFEIVEILIDIIQRIDDE 828 Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 67/299 (22%), Positives = 129/299 (43%), Gaps = 49/299 (16%) Query 632 DRGQELRVVLKVL-----DPSHHDIALAFYETASLMSQVS-HTHLAFVHGVCV-RGPENI 684 +R ++V +K++ D + HD F + +M + H ++ + G+C +GP + Sbjct 575 NRSNPIKVAVKMMRDDFSDSNVHD----FVKEMEIMKHIGRHPNVIQLLGLCTQKGPLRV 630 Query 685 MVTEYVEHGPLDVWLRRER----------GHVPMAWKMVVAQQLASALSYLENKNLVHGN 734 +V E +G L ++R + G+ + + Q+A ++YL ++++VH + Sbjct 631 IV-ELAPYGNLRDFVRAKNKKYSKSKKIIGNFTSSILCTYSLQIARGMTYLASRSVVHRD 689 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANS 790 + RNIL+ G +K++D G V + + + + W+APE L Sbjct 690 LSARNILV-------GEHFEMKIADFGLTRIVDYYYRKKTDGILPVKWMAPEALL--EKK 740 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP--QLATLTSQC 848 +T D W +G L EI G++P + P + ++ + P+P ++ L C Sbjct 741 YTTKSDVWSYGILLWEIFTLGDSPYSAILPEKVVDLIRKGFQNPKPELANFEIYRLMQHC 800 Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK--RYLKKIRDLGE 905 + RP+F I+ L D++ D P + ++H YLK D E Sbjct 801 WSLSSENRPNFFEIVEILI--------DIIQRIDDEP--EENIYHSELNYLKMESDYLE 849 >sp|P29319|EPHA3_MOUSE Ephrin type-A receptor 3 OS=Mus musculus OX=10090 GN=Epha3 PE=1 SV=1 Length=983 Score = 145 bits (365), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 87/270 (32%), Positives = 139/270 (51%), Gaps = 21/270 (8%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG+V S P+ VA+K LK + R + E I+ H +II+ Sbjct 627 VGAGEFGEVCSGRLKLPSKKEIS--VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIR 684 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHY 1019 +G K +V EY+ GSL +L +H + QL+ + I GM YL Y Sbjct 685 LEGVVTKS--KPEMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGY 742 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W +PE + KF Sbjct 743 VHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAMSYRKFT 802 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 ASDVWS+G+ L+E++++ + S QM+ + + ++ RLP P Sbjct 803 SASDVWSYGIVLWEVMSYGERPYS--------------QMSNQDVIKAVDERYRLPPPMD 848 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 CP +Y LM +CW+ + + RP FE ++ IL Sbjct 849 CPAALYQLMLDCWQKDRNNRPKFEQIVSIL 878 Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 68/245 (28%), Positives = 111/245 (45%), Gaps = 19/245 (8%) Query 635 QELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +E+ V +K L + + F AS+M Q H ++ + GV + ++VTEY+E+G Sbjct 646 KEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPEMIVTEYMENG 705 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 LD +LR+ + + + + +AS + YL + VH ++ RNIL+ ++ Sbjct 706 SLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILI-------NSNL 758 Query 754 FIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLE 806 K+SD G+ E R +IP W +PE + ++A D W +G L E Sbjct 759 VCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAM--SYRKFTSASDVWSYGIVLWE 816 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILR 864 + GE P S + ++RLP P CP L L C + RP F I+ Sbjct 817 VMSYGERPYSQMSNQDVIKAVDERYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVS 876 Query 865 DLTRL 869 L +L Sbjct 877 ILDKL 881 >sp|P00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src OS=Gallus gallus OX=9031 GN=SRC PE=1 SV=4 Length=533 Score = 141 bits (355), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 91/272 (33%), Positives = 137/272 (50%), Gaps = 31/272 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++ Sbjct 273 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQL 325 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLHAQH 1018 E+ + +V EY+ GSL D+L + +G L QL+ A QI GMAY+ + Sbjct 326 YAVV---SEEPIYIVTEYMSKGSLLDFL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMN 381 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 Y+HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F Sbjct 382 YVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRF 439 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SDVWSFG+ L EL T + M + + +ERG R+P P Sbjct 440 TIKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPP 485 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +CP ++ LM CW + RPTFE L L+ Sbjct 486 ECPESLHDLMCQCWRKDPEERPTFEYLQAFLE 517 Score = 82.0 bits (201), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 348 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859 P E +R +R+P P CP+ L L QC +P +RP+F Sbjct 460 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTF 509 >sp|Q9YI66|TYRO3_DANRE Tyrosine-protein kinase receptor TYRO3 OS=Danio rerio OX=7955 GN=tyro3 PE=2 SV=1 Length=874 Score = 144 bits (364), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 107/337 (32%), Positives = 167/337 (50%), Gaps = 32/337 (9%) Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS--DPTVFHKRYLKKIRDLGEGHFGK 910 P + R+ R L P + D L +N D A D +F +R L R LG+G FG Sbjct 453 PVSFTAARSFNRQFPEL-PESTLDSLGINSDLKAKLQDVLIF-ERLLTLGRMLGKGEFGS 510 Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIKYKGCC-ED 968 V + + + +G+ VAVK LK D +E ++ +H ++I+ G Sbjct 511 VR-EAFLKSENNSGQKVAVKVLKTDINSSSDIEQCLKEAAYMKDFHHPNVIQLIGVSLHR 569 Query 969 QGEKSLQLVMEYVPL---GSLRDYLPRHSIG-----LAQLLL--FAQQICEGMAYLHAQH 1018 + ++ L + M +P G L +L +G ++Q +L F I GM YL ++ Sbjct 570 RAQQRLPIPMVILPFMKHGDLHTFLLMSRLGDEPFTVSQQILIQFMLDIARGMEYLSNKN 629 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRDLAARN +L+ + V + DFGL+K + G +YYR PV W A E L + + Sbjct 630 IIHRDLAARNCMLNENMSVCVADFGLSKKIYSG-DYYRQGSVSKLPVKWIALESLADNVY 688 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SDVW+FGVT++E++T Q+P G+ + + E L +GERL +P Sbjct 689 TTQSDVWAFGVTMWEIMTR---GQTP------YPGVENSE-----IYEYLIKGERLKQPP 734 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 CP ++Y +M +CW RP+F++LI L+ + K Sbjct 735 DCPADIYEIMHSCWSPVPKCRPSFQHLIDQLELLWAK 771 Score = 73.6 bits (179), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 73/259 (28%), Positives = 116/259 (45%), Gaps = 30/259 (12%) Query 631 RDRGQELRV-VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV------RGPEN 683 + GQ++ V VLK S DI E A+ M H ++ + GV + R P Sbjct 520 NNSGQKVAVKVLKTDINSSSDIEQCLKE-AAYMKDFHHPNVIQLIGVSLHRRAQQRLPIP 578 Query 684 IMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQ----LASALSYLENKNLVHGNVCGR 738 +++ +++HG L +L R G P + Q +A + YL NKN++H ++ R Sbjct 579 MVILPFMKHGDLHTFLLMSRLGDEPFTVSQQILIQFMLDIARGMEYLSNKNIIHRDLAAR 638 Query 739 NILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIP--WLAPECLPGGANSLS 792 N +L E S + ++D G+ G R+ V ++P W+A E L N + Sbjct 639 NCMLN-----ENMS--VCVADFGLSKKIYSGDYYRQGSVSKLPVKWIALESL--ADNVYT 689 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLT 850 T D W FG T+ EI G+ P SE + + RL + P CP + + C + Sbjct 690 TQSDVWAFGVTMWEIMTRGQTPYPGVENSEIYEYLIKGERLKQPPDCPADIYEIMHSCWS 749 Query 851 YEPTQRPSFRTILRDLTRL 869 P RPSF+ ++ L L Sbjct 750 PVPKCRPSFQHLIDQLELL 768 >sp|Q108U6|MET_LOXAF Hepatocyte growth factor receptor OS=Loxodonta africana OX=9785 GN=MET PE=3 SV=1 Length=1382 Score = 145 bits (366), Expect = 9e-34, Method: Compositional matrix adjust. Identities = 95/282 (34%), Positives = 146/282 (52%), Gaps = 23/282 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G GHFG V Y ++G ++ AVK+L S + E I++ H +++ Sbjct 1085 IGRGHFGCV--YHGTLLDNGDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLS 1142 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ + Sbjct 1143 LLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKF 1201 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKEYK 1077 +HRDLAARN +LD VK+ DFGLA+ V + EYY V + PV W A E L+ K Sbjct 1202 VHRDLAARNCMLDEKFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESLQTQK 1260 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFGV L+EL+T +PP + +T L +G RL +P Sbjct 1261 FTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLLQP 1306 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 + CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1307 EYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348 Score = 62.4 bits (150), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDVYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341 >sp|Q04736|YES_MOUSE Tyrosine-protein kinase Yes OS=Mus musculus OX=10090 GN=Yes1 PE=1 SV=3 Length=541 Score = 141 bits (355), Expect = 9e-34, Method: Compositional matrix adjust. Identities = 99/305 (32%), Positives = 147/305 (48%), Gaps = 32/305 (10%) Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 H L V TV P + A D + L+ LG+G FG+V + ++ T VA Sbjct 247 HKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK-----VA 301 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK G + QE I++ L H+ ++ E+ + +V E++ GSL D Sbjct 302 IKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVVS---EEPIYIVTEFMSKGSLLD 356 Query 989 YLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ + + KI DFGLA Sbjct 357 FLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLICKIADFGLA 416 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + Y R+ P+ W APE +F SDVWSFG+ EL+T Sbjct 417 RLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGR------ 468 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + M + E +ERG R+P P CP ++ LM CW+ + RPTFE + Sbjct 469 --------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYI 520 Query 1166 IPILK 1170 L+ Sbjct 521 QSFLE 525 Score = 73.9 bits (180), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 63/233 (27%), Positives = 106/233 (45%), Gaps = 19/233 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P + AF + A +M ++ H L ++ V P I VTE++ G L Sbjct 299 KVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEFMSKGSLLD 356 Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G ++ + + +A Q+A ++Y+E N +H ++ NIL+ G + K Sbjct 357 FLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILV-------GENLICK 409 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG E+ G Sbjct 410 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILQTELVTKG 467 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 P E +R +R+P P CP+ L L + C +P +RP+F I Sbjct 468 RVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYI 520 >sp|Q75ZY9|MET_CANLF Hepatocyte growth factor receptor OS=Canis lupus familiaris OX=9615 GN=MET PE=1 SV=1 Length=1382 Score = 145 bits (366), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 96/284 (34%), Positives = 143/284 (50%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T ND AVK+L S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS--PVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW A RP+F L+ + + + G+ Sbjct 1305 QPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGE 1348 Score = 60.5 bits (145), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 99/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C RPSF ++ ++ + Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAI 1341 >sp|Q07E01|MET_ORNAN Hepatocyte growth factor receptor OS=Ornithorhynchus anatinus OX=9258 GN=MET PE=3 SV=1 Length=1382 Score = 145 bits (365), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 95/284 (33%), Positives = 144/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T ND AVK+L + S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDNDDKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICLRR-EGSPLVVLPYMKHGDLRNFIRNESHNPTVKDLIGFGLQVAKGMKYLASK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTSKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP ++ +M CW A RP+F L+ + + + G+ Sbjct 1305 QPEYCPDPLFEVMLKCWHPNAEMRPSFSELVSKIAVIFSTFIGE 1348 Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 54/224 (24%), Positives = 97/224 (43%), Gaps = 22/224 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRREGSPLVVLPYMKHGDLRNFIRNE-SHNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFT-------VKVADFGLARDMYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L ++ D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESL--QTQKFTSKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866 + + RL +P CP L + +C RPSF ++ + Sbjct 1295 VYLLQGRRLLQPEYCPDPLFEVMLKCWHPNAEMRPSFSELVSKI 1338 >sp|P14085|SRC_AVIST Tyrosine-protein kinase transforming protein Src OS=Avian sarcoma virus (strain S2) OX=11882 GN=V-SRC PE=3 SV=3 Length=557 Score = 141 bits (356), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 91/272 (33%), Positives = 137/272 (50%), Gaps = 31/272 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++ Sbjct 273 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQL 325 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLHAQH 1018 E+ + +V EY+ GSL D+L + +G L QL+ A QI GMAY+ + Sbjct 326 YAVV---SEEPIYIVTEYMSKGSLLDFL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMN 381 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 Y+HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F Sbjct 382 YVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRF 439 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SDVWSFG+ L EL T + M + + +ERG R+P P Sbjct 440 TIKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPP 485 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +CP ++ LM CW + RPTFE L L+ Sbjct 486 ECPESLHDLMCQCWRKDPEERPTFEYLQAFLE 517 Score = 82.0 bits (201), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 348 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859 P E +R +R+P P CP+ L L QC +P +RP+F Sbjct 460 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTF 509 >sp|P15054|SRC_AVIS2 Tyrosine-protein kinase transforming protein Src OS=Avian sarcoma virus (strain PR2257) OX=11879 GN=V-SRC PE=3 SV=3 Length=587 Score = 142 bits (357), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 99/306 (32%), Positives = 149/306 (49%), Gaps = 34/306 (11%) Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 H L +V T P + A D + L+ LG+G FG+V + ++ T VA Sbjct 239 HRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTT-----RVA 293 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK G + QE +++ L HE +++ E+ + +V EY+ GSL D Sbjct 294 IKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS---EEPIYIVTEYMSKGSLLD 348 Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 349 FL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW + RPTFE Sbjct 461 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEY 511 Query 1165 LIPILK 1170 L L+ Sbjct 512 LQAFLE 517 Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 348 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859 P E +R +R+P P CP+ L L QC +P +RP+F Sbjct 460 RVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTF 509 >sp|Q4JIM5|ABL2_MOUSE Tyrosine-protein kinase ABL2 OS=Mus musculus OX=10090 GN=Abl2 PE=1 SV=1 Length=1182 Score = 145 bits (365), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 93/287 (32%), Positives = 144/287 (50%), Gaps = 27/287 (9%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 TV SP D + + LG G +G+V + + + VAVK K D Sbjct 270 TVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYS----LTVAVKTFKEDT-- 323 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSI 995 + +E +++ + H ++++ G C E +V EY+P G+L DYL R + Sbjct 324 MEVEEFLKEAAVMKEIKHPNLVQLLGVC--TLEPPFYIVTEYMPYGNLLDYLRECSREEV 381 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 LL A QI M YL +++IHRDLAARN L+ + +VK+ DFGL++ + + Y Sbjct 382 TAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDTY 439 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 P+ W APE L F SDVW+FGV L+E+ T+ S P ++L Sbjct 440 TAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMS----PYPGIDLS--- 492 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 ++ +LLE+G R+ +P+ CP +VY LM+ CW+ + RP+F Sbjct 493 -------QVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSF 532 Score = 93.6 bits (231), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 69/231 (30%), Positives = 108/231 (47%), Gaps = 18/231 (8%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 L V +K ++ F + A++M ++ H +L + GVC P +VTEY+ +G L Sbjct 312 LTVAVKTFKEDTMEVE-EFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLL 370 Query 697 VWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +LR R V + +A Q++SA+ YLE KN +H ++ RN L+ G + + Sbjct 371 DYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV-------GENHVV 423 Query 756 KLSDPGVG---LGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ G + P W APE L N+ S D W FG L EI Sbjct 424 KVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESL--AYNTFSIKSDVWAFGVLLWEIATY 481 Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859 G +P S+ ++ +R+ PE P++ L C + P RPSF Sbjct 482 GMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSF 532 >sp|Q02977|YRK_CHICK Proto-oncogene tyrosine-protein kinase Yrk OS=Gallus gallus OX=9031 GN=YRK PE=2 SV=2 Length=536 Score = 141 bits (355), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 93/277 (34%), Positives = 139/277 (50%), Gaps = 29/277 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ ++ LG G FG+V + ++ T VAVK LK G + +E I++ L H Sbjct 270 LQLLQKLGNGQFGEVWMGTWNGTTK-----VAVKTLKP--GTMSPEAFLEEAQIMKRLRH 322 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAY 1013 + +++ E+ + +V E++ GSL D+L + L QL+ A QI GMAY Sbjct 323 DKLVQLYAVVS---EEPIYIVTEFMSQGSLLDFLKDGDGRYLKLPQLVDMAAQIAAGMAY 379 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + +YIHRDL A N+L+ ++ + KI DFGLA+ + + Y R+ P+ W APE Sbjct 380 IERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAA 437 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 KF SDVWSFG+ L EL+T + M + E +ERG R Sbjct 438 LFGKFTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYR 483 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + P CP ++ +M CW+ E RPTFE L L+ Sbjct 484 MQCPGGCPPSLHDVMVQCWKREPEERPTFEYLQSFLE 520 Score = 75.5 bits (184), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 64/233 (27%), Positives = 106/233 (45%), Gaps = 19/233 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P AF E A +M ++ H L ++ V P I VTE++ G L Sbjct 294 KVAVKTLKPGTMSPE-AFLEEAQIMKRLRHDKLVQLYAVVSEEPIYI-VTEFMSQGSLLD 351 Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G ++ + + +A Q+A+ ++Y+E N +H ++ NIL+ G + K Sbjct 352 FLKDGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILV-------GDNLVCK 404 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 405 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALFGKFTIKS--DVWSFGILLTELVTKG 462 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEPTQRPSFRTI 862 P + E +R +R+ P C P L + QC EP +RP+F + Sbjct 463 RVPYPGMNNREVLEQVERGYRMQCPGGCPPSLHDVMVQCWKREPEERPTFEYL 515 >sp|P97523|MET_RAT Hepatocyte growth factor receptor OS=Rattus norvegicus OX=10116 GN=Met PE=1 SV=1 Length=1382 Score = 145 bits (365), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 95/284 (33%), Positives = 146/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T +DG AVK+L + S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDSDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLVSK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITIYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+ L+ + ++ + G+ Sbjct 1305 QPEYCPDALYEVMLKCWHPKAEMRPSVSELVSRISSIFSTFIGE 1348 Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 54/227 (24%), Positives = 99/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1184 GFGLQVAKGMKYLVSKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPS ++ ++ + Sbjct 1295 IYLLQGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSVSELVSRISSI 1341 >sp|P07947|YES_HUMAN Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 Length=543 Score = 141 bits (355), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 99/305 (32%), Positives = 147/305 (48%), Gaps = 32/305 (10%) Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 H L V TV P + A D + L+ LG+G FG+V + ++ T VA Sbjct 249 HKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK-----VA 303 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK G + QE I++ L H+ ++ E+ + +V E++ GSL D Sbjct 304 IKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVVS---EEPIYIVTEFMSKGSLLD 358 Query 989 YLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ + + KI DFGLA Sbjct 359 FLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLA 418 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + Y R+ P+ W APE +F SDVWSFG+ EL+T Sbjct 419 RLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGR------ 470 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + M + E +ERG R+P P CP ++ LM CW+ + RPTFE + Sbjct 471 --------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYI 522 Query 1166 IPILK 1170 L+ Sbjct 523 QSFLE 527 Score = 73.6 bits (179), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 63/233 (27%), Positives = 106/233 (45%), Gaps = 19/233 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P + AF + A +M ++ H L ++ V P I VTE++ G L Sbjct 301 KVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEFMSKGSLLD 358 Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G ++ + + +A Q+A ++Y+E N +H ++ NIL+ G + K Sbjct 359 FLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILV-------GENLVCK 411 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG E+ G Sbjct 412 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILQTELVTKG 469 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 P E +R +R+P P CP+ L L + C +P +RP+F I Sbjct 470 RVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYI 522 >sp|Q28923|YES_CANLF Tyrosine-protein kinase Yes OS=Canis lupus familiaris OX=9615 GN=YES1 PE=1 SV=3 Length=539 Score = 140 bits (354), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 99/305 (32%), Positives = 146/305 (48%), Gaps = 32/305 (10%) Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 H L V TV P + A D + L+ LG+G FG+V + ++ T VA Sbjct 245 HKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK-----VA 299 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK G + QE I++ L H+ ++ E+ + +V E++ GSL D Sbjct 300 IKTLK--LGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVS---EEPIYIVTEFMSKGSLLD 354 Query 989 YLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ + + KI DFGLA Sbjct 355 FLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLA 414 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + Y R+ P+ W APE +F SDVWSFG+ EL T Sbjct 415 RLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELTTKGR------ 466 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + M + E +ERG R+P P CP ++ LM CW+ + RPTFE + Sbjct 467 --------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYI 518 Query 1166 IPILK 1170 L+ Sbjct 519 QSFLE 523 Score = 70.9 bits (172), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 59/217 (27%), Positives = 99/217 (46%), Gaps = 18/217 (8%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKM 712 AF + A +M ++ H L ++ V P I VTE++ G L +L+ G ++ + + Sbjct 312 AFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEFMSKGSLLDFLKEGDGKYLKLPQLV 370 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 +A Q+A ++Y+E N +H ++ NIL+ G + K++D G+ E Sbjct 371 DMAAQIADGMAYIERMNYIHRDLRAANILV-------GENLVCKIADFGLARLIEDNEYT 423 Query 773 VER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 + I W APE G ++ + D W FG E+ G P E Sbjct 424 ARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILQTELTTKGRVPYPGMVNREVLEQV 481 Query 828 QRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 +R +R+P P CP+ L L + C +P +RP+F I Sbjct 482 ERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYI 518 >sp|P13116|SRC2_XENLA Tyrosine-protein kinase Src-2 OS=Xenopus laevis OX=8355 GN=src-b PE=2 SV=3 Length=532 Score = 140 bits (354), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 91/272 (33%), Positives = 136/272 (50%), Gaps = 31/272 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+V + ++ T VA+K LK G + QE +++ L HE +++ Sbjct 272 LGQGCFGEVWMGTWNGTT-----RVAIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQL 324 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLHAQH 1018 E+ + +V EY+ GSL D+L + +G L QL+ A QI GMAY+ + Sbjct 325 YAVVS---EEPIYIVTEYMSKGSLLDFL-KGEMGRYLRLPQLVDMAAQIASGMAYVERMN 380 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 Y+HRDL A N+L+ + + K+ DFGLA+ + + Y R+ P+ W APE +F Sbjct 381 YVHRDLRAANILVGENLVCKVADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRF 438 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SDVWSFG+ L EL T + M + + +ERG R+P P Sbjct 439 TIKSDVWSFGILLTELTTKGR--------------VPYPGMVNREVLDQVERGYRMPCPP 484 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 CP ++ LM CW + RPTFE L L+ Sbjct 485 DCPESLHDLMFQCWRKDPEERPTFEYLQAFLE 516 Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 70/230 (30%), Positives = 106/230 (46%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I VTEY+ G L Sbjct 290 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYI-VTEYMSKGSLLD 347 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 348 FLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 400 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 401 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 458 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSF 859 P E +R +R+P P CP+ L L QC +P +RP+F Sbjct 459 RVPYPGMVNREVLDQVERGYRMPCPPDCPESLHDLMFQCWRKDPEERPTF 508 >sp|P54757|EPHA5_RAT Ephrin type-A receptor 5 OS=Rattus norvegicus OX=10116 GN=Epha5 PE=1 SV=1 Length=1005 Score = 144 bits (363), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 93/294 (32%), Positives = 149/294 (51%), Gaps = 31/294 (11%) Query 888 DPTVFHKRYLKKI--------RDLGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCG 937 DPT + K+I R +G G FG+V C G E+ VA K LK Sbjct 660 DPTQAVHEFGKEIEASCITIERVIGAGEFGEV---CSGRLKLPGKRELPVATKTLKVGYT 716 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995 + R + E I+ H +II +G K + +V EY+ GSL +L ++ Sbjct 717 EKQRRDFLSEASIMGQFDHPNIIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQF 774 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL++ + + E Sbjct 775 TVIQLVGMLRGIAAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAA 834 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 G P+ W APE + KF ASDVWS+G+ ++E++++ + P Sbjct 835 YTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSY---GERP----------- 880 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 +MT + + +E G RLP P CP +Y LM +CW+ + + RP F++++ +L Sbjct 881 YWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDDIVNML 934 Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 79/286 (28%), Positives = 128/286 (45%), Gaps = 33/286 (12%) Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSH 667 RV G+G E G++ +PG+ +EL V K L + + F AS+M Q H Sbjct 681 RVIGAG--EFGEVCSGRLKLPGK---RELPVATKTLKVGYTEKQRRDFLSEASIMGQFDH 735 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 ++ + GV + ++VTEY+E+G LD +L++ G + + + + +A+ + YL + Sbjct 736 PNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLSD 795 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIP--WLA 780 VH ++ RNIL+ ++ K+SD G+ E R +IP W A Sbjct 796 MGYVHRDLAARNILI-------NSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTA 848 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP 839 PE + ++A D W +G + E+ GE P + + + +RLP P CP Sbjct 849 PEAI--AFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMDCP 906 Query 840 -QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884 L L C + RP F I+ N+ D L NP S Sbjct 907 AALYQLMLDCWQKDRNSRPKFDDIV---------NMLDKLIRNPSS 943 >sp|P23049|SEA_AVIET Tyrosine-protein kinase transforming protein SEA OS=Avian erythroblastosis virus (strain S13) OX=11863 GN=V-SEA PE=3 SV=2 Length=370 Score = 137 bits (344), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 99/292 (34%), Positives = 145/292 (50%), Gaps = 39/292 (13%) Query 901 RDLGEGHFGKVSLYCY-DPTNDGTGEM-VAVKALKADCGPQHRSGWKQEID-------IL 951 R +G GHFG V Y DP G + AVK+L HR + +E++ ++ Sbjct 64 RVIGRGHFGSVYHGTYMDPL---LGNLHCAVKSL-------HRITYLEEVEEFLREGILM 113 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICE 1009 + +H ++ G C + L +V+ Y+ G LR ++ S + +L+ F Q+ Sbjct 114 KGFHHPQVLSLLGVCLPRHGLPL-VVLPYMRHGDLRHFVRAQERSPTVKELIGFGLQVAL 172 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE--DGDSPVFW 1067 GM YL + ++HRDLAARN +LD VK+ DFGLA+ V G EYY +R+ PV W Sbjct 173 GMEYLAQKKFVHRDLAARNCMLDETLTVKVADFGLARDV-FGKEYYSIRQHRHAKLPVRW 231 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 A E L+ KF SDVWSFGV ++ELLT S ++ + Sbjct 232 MALESLQTQKFTTKSDVWSFGVLMWELLTRGASPYP--------------EVDPYDMARY 277 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L RG RLP+P CP +Y +M +CW RP+F L+ L+ V +G+ Sbjct 278 LLRGRRLPQPQPCPDTLYGVMLSCWAPTPEERPSFSGLVCELERVLASLEGE 329 Score = 72.4 bits (176), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 59/226 (26%), Positives = 97/226 (43%), Gaps = 20/226 (9%) Query 655 FYETASLMSQVSHTHLAFVHGVCV-RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F LM H + + GVC+ R ++V Y+ HG L ++R + + + Sbjct 106 FLREGILMKGFHHPQVLSLLGVCLPRHGLPLVVLPYMRHGDLRHFVRAQERSPTVKELIG 165 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----- 768 Q+A + YL K VH ++ RN +L + +K++D G+ Sbjct 166 FGLQVALGMEYLAQKKFVHRDLAARNCML-------DETLTVKVADFGLARDVFGKEYYS 218 Query 769 -REERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 R+ R ++P W+A E L +T D W FG + E+ G +P P + Sbjct 219 IRQHRHAKLPVRWMALESL--QTQKFTTKSDVWSFGVLMWELLTRGASPYPEVDPYDMAR 276 Query 826 FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + R RLP+P CP L + C P +RPSF ++ +L R+ Sbjct 277 YLLRGRRLPQPQPCPDTLYGVMLSCWAPTPEERPSFSGLVCELERV 322 >sp|Q60629|EPHA5_MOUSE Ephrin type-A receptor 5 OS=Mus musculus OX=10090 GN=Epha5 PE=1 SV=2 Length=876 Score = 143 bits (361), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 87/273 (32%), Positives = 142/273 (52%), Gaps = 23/273 (8%) Query 901 RDLGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 R +G G FG+V C G E+ VA+K LK + R + E I+ H + Sbjct 518 RVIGAGEFGEV---CSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPN 574 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHA 1016 II +G K + +V EY+ GSL +L ++ + QL+ + I GM YL Sbjct 575 IIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLSD 632 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W APE + Sbjct 633 MGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFR 692 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 KF +SDVWS+G+ ++E++++ + P +MT + + +E G RLP Sbjct 693 KFTSSSDVWSYGIVMWEVVSY---GERP-----------YWEMTNQDVIKAVEEGYRLPS 738 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P CP +Y LM +CW+ + + RP F+ ++ +L Sbjct 739 PMDCPAALYQLMLDCWQKDRNSRPKFDEIVNML 771 Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 78/288 (27%), Positives = 131/288 (45%), Gaps = 37/288 (13%) Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSH 667 RV G+G E G++ +PG+ +EL V +K L + + F AS+M Q H Sbjct 518 RVIGAG--EFGEVCSGRLKLPGK---RELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDH 572 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 ++ + GV + ++VTEY+E+G LD +L++ G + + + + +A+ + YL + Sbjct 573 PNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLSD 632 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-------RVERIP--W 778 VH ++ RNIL+ ++ K+SD GL + ++ R +IP W Sbjct 633 MGYVHRDLAARNILI-------NSNLVCKVSD--FGLSRVLEDDPEAAYTTRGGKIPIRW 683 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-S 837 APE + +++ D W +G + E+ GE P + + + +RLP P Sbjct 684 TAPEAI--AFRKFTSSSDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSPMD 741 Query 838 CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884 CP L L C + RP F I+ N+ D L NP S Sbjct 742 CPAALYQLMLDCWQKDRNSRPKFDEIV---------NMLDKLIRNPSS 780 >sp|O13146|EPHA3_DANRE Ephrin type-A receptor 3 OS=Danio rerio OX=7955 GN=epha3 PE=1 SV=1 Length=981 Score = 144 bits (362), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 93/293 (32%), Positives = 147/293 (50%), Gaps = 29/293 (10%) Query 888 DPTVFHKRYLKKI--------RDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGP 938 DP + + K+I R +G G FG+V S P+ VA+K+LKA Sbjct 609 DPNQAVRDFAKEIEVSNIRIERVIGAGEFGEVCSGRLRLPSKREI--QVAIKSLKAGYSE 666 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IG 996 R + E I+ H +II+ +G K + +V EY+ GSL +L +H Sbjct 667 HQRRDFLSEASIMGQFDHPNIIRLEGVVTRC--KPVMIVTEYMENGSLDTFLKKHDGQFT 724 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 + QLL + I GM YL +Y+HRDLAARN+L++ + + K+ DFGL++ + + E Sbjct 725 VIQLLGMLRGIAAGMQYLSEMNYVHRDLAARNILVNRNLVCKVSDFGLSRVLEDDPEAAY 784 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 G P+ W APE + KF ASDVWS+G+ ++E++++ + P Sbjct 785 TTRGGKIPIRWTAPEAITYRKFTSASDVWSYGIVMWEVISY---GERP-----------Y 830 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 +M+ + + ++ G RLP P CP ++ LM +CWE S RP F ++ L Sbjct 831 WEMSNQDVIKAVDEGYRLPAPMDCPVVLHQLMLDCWEKNRSDRPKFGQIVNTL 883 Score = 91.7 bits (226), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 71/245 (29%), Positives = 112/245 (46%), Gaps = 19/245 (8%) Query 635 QELRVVLKVLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +E++V +K L + + F AS+M Q H ++ + GV R ++VTEY+E+G Sbjct 651 REIQVAIKSLKAGYSEHQRRDFLSEASIMGQFDHPNIIRLEGVVTRCKPVMIVTEYMENG 710 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 LD +L++ G + + + + +A+ + YL N VH ++ RNIL+ R + Sbjct 711 SLDTFLKKHDGQFTVIQLLGMLRGIAAGMQYLSEMNYVHRDLAARNILVNR-------NL 763 Query 754 FIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLE 806 K+SD G+ E R +IP W APE + ++A D W +G + E Sbjct 764 VCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIT--YRKFTSASDVWSYGIVMWE 821 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILR 864 + GE P S + +RLP P CP L L C + RP F I+ Sbjct 822 VISYGERPYWEMSNQDVIKAVDEGYRLPAPMDCPVVLHQLMLDCWEKNRSDRPKFGQIVN 881 Query 865 DLTRL 869 L RL Sbjct 882 TLDRL 886 >sp|Q7YR43|DDR1_PANTR Epithelial discoidin domain-containing receptor 1 OS=Pan troglodytes OX=9598 GN=DDR1 PE=3 SV=1 Length=909 Score = 143 bits (361), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 99/309 (32%), Positives = 141/309 (46%), Gaps = 47/309 (15%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTND------------GTGEMVAVKALKADCGPQ 939 F + L+ LGEG FG+V L D D G +VAVK L+ D Sbjct 601 FPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKN 660 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------ 993 R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L H Sbjct 661 ARNDFLKEVKIMSRLKDPNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSAHQLEDKA 718 Query 994 --------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 +I LL A QI GM YL +++HRDLA RN L+ + +KI Sbjct 719 AEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKI 778 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+L C Sbjct 779 ADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCR 837 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER---LPRPDKCPCEVYHLMKNCWETEA 1156 + + G + + E R L RP CP +Y LM CW E+ Sbjct 838 A---------QPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRES 888 Query 1157 SFRPTFENL 1165 RP F L Sbjct 889 EQRPPFSQL 897 Score = 76.6 bits (187), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 76/270 (28%), Positives = 121/270 (45%), Gaps = 44/270 (16%) Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +G L V +K+L P A F + +MS++ ++ + GVCV+ M+T+Y+E Sbjct 642 KGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYME 701 Query 692 HGPLDVWLRRER------------GHVP----MAWKMV--VAQQLASALSYLENKNLVHG 733 +G L+ +L + G +++ M+ VA Q+AS + YL N VH Sbjct 702 NGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHR 761 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGG 787 ++ RN L+ G + IK++D G+ + + V I W+A EC+ G Sbjct 762 DLATRNCLV-------GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG 814 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-----EHFYQRQHRLP----EPSC 838 +TA D W FG TL E+ A + E+ F++ Q R P+C Sbjct 815 --KFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPAC 872 Query 839 PQ-LATLTSQCLTYEPTQRPSFRTILRDLT 867 PQ L L +C + E QRP F + R L Sbjct 873 PQGLYELMLRCWSRESEQRPPFSQLHRFLA 902 >sp|Q08345|DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 OS=Homo sapiens OX=9606 GN=DDR1 PE=1 SV=1 Length=913 Score = 143 bits (361), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 99/309 (32%), Positives = 141/309 (46%), Gaps = 47/309 (15%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTND------------GTGEMVAVKALKADCGPQ 939 F + L+ LGEG FG+V L D D G +VAVK L+ D Sbjct 605 FPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDATKN 664 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------ 993 R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L H Sbjct 665 ARNDFLKEVKIMSRLKDPNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSAHQLEDKA 722 Query 994 --------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 +I LL A QI GM YL +++HRDLA RN L+ + +KI Sbjct 723 AEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKI 782 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+L C Sbjct 783 ADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCR 841 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER---LPRPDKCPCEVYHLMKNCWETEA 1156 + + G + + E R L RP CP +Y LM CW E+ Sbjct 842 A---------QPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRES 892 Query 1157 SFRPTFENL 1165 RP F L Sbjct 893 EQRPPFSQL 901 Score = 76.6 bits (187), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 76/270 (28%), Positives = 121/270 (45%), Gaps = 44/270 (16%) Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +G L V +K+L P A F + +MS++ ++ + GVCV+ M+T+Y+E Sbjct 646 KGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYME 705 Query 692 HGPLDVWLRRER------------GHVP----MAWKMV--VAQQLASALSYLENKNLVHG 733 +G L+ +L + G +++ M+ VA Q+AS + YL N VH Sbjct 706 NGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHR 765 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGG 787 ++ RN L+ G + IK++D G+ + + V I W+A EC+ G Sbjct 766 DLATRNCLV-------GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG 818 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-----EHFYQRQHRLP----EPSC 838 +TA D W FG TL E+ A + E+ F++ Q R P+C Sbjct 819 --KFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPAC 876 Query 839 PQ-LATLTSQCLTYEPTQRPSFRTILRDLT 867 PQ L L +C + E QRP F + R L Sbjct 877 PQGLYELMLRCWSRESEQRPPFSQLHRFLA 906 >sp|P06213|INSR_HUMAN Insulin receptor OS=Homo sapiens OX=9606 GN=INSR PE=1 SV=4 Length=1382 Score = 144 bits (363), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 94/283 (33%), Positives = 146/283 (52%), Gaps = 29/283 (10%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 +R+LG+G FG V G E VAVK + + R + E +++ H Sbjct 1026 LRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHH 1085 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------PRHSIGLAQLLLFAQQI 1007 +++ G +G+ +L +VME + G L+ YL R L +++ A +I Sbjct 1086 VVRLLGVVS-KGQPTL-VVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEI 1143 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 +GMAYL+A+ ++HRDLAARN ++ +D VKIGDFG+ + + E +YYR G PV W Sbjct 1144 ADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYET-DYYRKGGKGLLPVRW 1202 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE LK+ F +SD+WSFGV L+E+ + + G++ Q + + Sbjct 1203 MAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQ---------GLSNEQ-----VLKF 1248 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + G L +PD CP V LM+ CW+ RPTF ++ +LK Sbjct 1249 VMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLK 1291 Score = 91.3 bits (225), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 82/301 (27%), Positives = 128/301 (43%), Gaps = 46/301 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +++IT L LGQG+ VYEG R G+ E RV +K Sbjct 1018 VSREKITLLRELGQGSFGMVYEGNARDIIKGE-------------------AETRVAVKT 1058 Query 644 LDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 ++ S + F AS+M + H+ + GV +G ++V E + HG L +LR Sbjct 1059 VNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSL 1118 Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 R P +M+ +A ++A ++YL K VH ++ RN ++A Sbjct 1119 RPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAH-------DF 1171 Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+ D G+ + + + + W+APE L G +T+ D W FG L EI Sbjct 1172 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGV--FTTSSDMWSFGVVLWEI 1229 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQLAT-LTSQCLTYEPTQRPSFRTILRD 865 E P Q S + F L +P +CP+ T L C + P RP+F I+ Sbjct 1230 TSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNL 1289 Query 866 L 866 L Sbjct 1290 L 1290 >sp|Q93105|INSR_AEDAE Insulin-like receptor OS=Aedes aegypti OX=7159 GN=InR PE=2 SV=2 Length=1393 Score = 144 bits (363), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 98/305 (32%), Positives = 155/305 (51%), Gaps = 35/305 (11%) Query 880 VNPDSPASDPTV----FHKRYLKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKA 934 VNPD V + ++ ++ +LG+G FG V + + A+K + Sbjct 1004 VNPDYAGVQYKVDDWEVERNHIIQLEELGQGSFGMVYKGILTQLRGEKCNQPCAIKTVNE 1063 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994 + + + E +++ H+++ G QG+ +L ++ME + G L+ YL RH Sbjct 1064 SATAREKDSFLLEASVMKQFNTHHVVRLLGVVS-QGDPTL-VIMELMANGDLKSYLRRHR 1121 Query 995 IG-------------LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 L Q++ A +I +GMAYL A+ ++HRDLAARN ++ +D VKIGD Sbjct 1122 PDYENGEDPSPQPPTLRQIIQMAIEIADGMAYLSAKKFVHRDLAARNCMVADDMTVKIGD 1181 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FG+ + + E +YYR G PV W APE LK+ F +SDV+S+GV L+E+ T Sbjct 1182 FGMTRDIYE-TDYYRKGTKGFLPVRWMAPESLKDGIFSSSSDVFSYGVVLWEMATLA--- 1237 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 S P + G+ Q VLR + G + RP+ CP +Y+LM+ CW+ + RPT Sbjct 1238 -SQPYQ-----GLTNDQ--VLR---YVIDGGVMERPENCPDNLYNLMRRCWQHRPTARPT 1286 Query 1162 FENLI 1166 F +I Sbjct 1287 FMEII 1291 Score = 77.0 bits (188), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 77/305 (25%), Positives = 128/305 (42%), Gaps = 52/305 (17%) Query 584 VDQKEITQLSHLGQGTRTNVYEG---RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 V++ I QL LGQG+ VY+G +LR E P K +E +D Sbjct 1020 VERNHIIQLEELGQGSFGMVYKGILTQLRGEKCNQPCAIKTVNESATAREKD-------- 1071 Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 +F AS+M Q + H+ + GV +G +++ E + +G L +LR Sbjct 1072 -------------SFLLEASVMKQFNTHHVVRLLGVVSQGDPTLVIMELMANGDLKSYLR 1118 Query 701 R-----ERGHVP------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 R E G P + + +A ++A ++YL K VH ++ RN ++A Sbjct 1119 RHRPDYENGEDPSPQPPTLRQIIQMAIEIADGMAYLSAKKFVHRDLAARNCMVA------ 1172 Query 750 GTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGANSLSTAMDKWGFGAT 803 +K+ D G+ R+ +P W+APE L G S++ D + +G Sbjct 1173 -DDMTVKIGDFGMTRDIYETDYYRKGTKGFLPVRWMAPESLKDGI--FSSSSDVFSYGVV 1229 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRT 861 L E+ P Q + + + + P +CP L L +C + PT RP+F Sbjct 1230 LWEMATLASQPYQGLTNDQVLRYVIDGGVMERPENCPDNLYNLMRRCWQHRPTARPTFME 1289 Query 862 ILRDL 866 I+ +L Sbjct 1290 IISEL 1294 >sp|Q9I7F7|ACKL_DROME Activated Cdc42 kinase-like OS=Drosophila melanogaster OX=7227 GN=Ack-like PE=1 SV=3 Length=1337 Score = 144 bits (363), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 94/272 (35%), Positives = 142/272 (52%), Gaps = 29/272 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 + LG G FG V + N+ VA+K L + + + +E I+ ++ HE+I+ Sbjct 137 KQLGTGEFGIVQQGVWSNGNERI--QVAIKCLCRERMQSNPMEFLKEAAIMHSIEHENIV 194 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-----FAQQICEGMAYLH 1015 + G SL LV E L SL + L + ++ L + FA QIC GM YL Sbjct 195 RLYGVV--LATDSLMLVTELAHLRSLLECLKDSGLRVSFLTIPTLCEFALQICNGMRYLE 252 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD--SPVFWYAPECL 1073 + IHRDLAARN+L+ + VKI DFGL++A+ G +YY+ + + P+ W APEC+ Sbjct 253 QKRLIHRDLAARNILVFSKDKVKISDFGLSRALGVGKDYYKTNFNVNLKLPIAWCAPECI 312 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ-GQMTVLRLTELLE--R 1130 +F ASDVW+FGV L+E+ ++ G +T L++ E ++ Sbjct 313 NYLRFTNASDVWAFGVCLWEMFSY---------------GFQPWAALTGLQILEAIDAPN 357 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 +RL +PD CP E Y LM CW+ +A+ RP F Sbjct 358 YQRLEQPDCCPSEYYTLMMKCWQDDAAKRPRF 389 Score = 66.6 bits (161), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 69/276 (25%), Positives = 115/276 (42%), Gaps = 39/276 (14%) Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-----DVWLRRERGHVP 707 + F + A++M + H ++ ++GV + ++VTE L D LR +P Sbjct 176 MEFLKEAAIMHSIEHENIVRLYGVVLATDSLMLVTELAHLRSLLECLKDSGLRVSFLTIP 235 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VG 763 + + Q+ + + YLE K L+H ++ RNIL+ + +K+SD G +G Sbjct 236 TLCEFAL--QICNGMRYLEQKRLIHRDLAARNILVF-------SKDKVKISDFGLSRALG 286 Query 764 LGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP---- 814 +G + I W APEC+ + A D W FG L E+ G P Sbjct 287 VGKDYYKTNFNVNLKLPIAWCAPECI--NYLRFTNASDVWAFGVCLWEMFSYGFQPWAAL 344 Query 815 --LQSRSPSEKEHFYQRQHRLPEPSC--PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 LQ + ++ RL +P C + TL +C + +RP F I L ++ Sbjct 345 TGLQILEAIDAPNY----QRLEQPDCCPSEYYTLMMKCWQDDAAKRPRFGEIYDQLPDMK 400 Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906 P L V VN P D ++ + + + D G Sbjct 401 PEQLKAV--VNCTEPKKDHLLYRQGDIISVLDRNTG 434 >sp|P97504|BMX_MOUSE Cytoplasmic tyrosine-protein kinase BMX OS=Mus musculus OX=10090 GN=Bmx PE=2 SV=1 Length=651 Score = 141 bits (356), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 90/278 (32%), Positives = 139/278 (50%), Gaps = 27/278 (10%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +++LG G FG V L + D VAVK +K G + QE + L H + Sbjct 396 LKELGNGQFGVVQLGQWKGQYD-----VAVKMIKE--GAMSEDEFFQEAQTMMKLSHPKL 448 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQ 1017 +K+ G C + + +V EY+ G L +YL H GL QLL +CEGMA+L + Sbjct 449 VKFYGVCSKK--YPIYIVTEYITNGCLLNYLKSHGKGLESCQLLEMCYDVCEGMAFLESH 506 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +IHRDLAARN L+D+D VK+ DFG+ + V + Y PV W APE +K Sbjct 507 QFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQ--YVSSVGTKFPVKWSAPEVFHYFK 564 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + SDVW+FG+ ++E+ + + P + V+++++ G RL RP Sbjct 565 YSSKSDVWAFGILMWEVFS---LGKQP-------YDLYDNSEVVVKVSQ----GHRLYRP 610 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 +Y +M +CW RPTF+ L+ ++ + E+ Sbjct 611 QLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPLREQ 648 Score = 66.2 bits (160), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 57/230 (25%), Positives = 101/230 (44%), Gaps = 24/230 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F++ A M ++SH L +GVC + +VTEY+ +G L +L+ + + + Sbjct 433 FFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSHGKGLESCQLLEM 492 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + +++LE+ +H ++ RN L+ + +K+SD G+ L ++ V Sbjct 493 CYDVCEGMAFLESHQFIHRDLAARNCLV-------DSDLSVKVSDFGMTRYVLD-DQYVS 544 Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 + W APE S+ D W FG + E+ G+ P SE Sbjct 545 SVGTKFPVKWSAPEVF--HYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVS 602 Query 829 RQHRLPEPSCPQLATLTSQCLTYE-----PTQRPSFRTILRDLTRLQPHN 873 + HRL PQLA+ T + Y P +RP+F+ +L + L+ + Sbjct 603 QGHRLYR---PQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPLREQD 649 >sp|Q07E48|MET_DASNO Hepatocyte growth factor receptor OS=Dasypus novemcinctus OX=9361 GN=MET PE=3 SV=1 Length=1381 Score = 144 bits (362), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 95/284 (33%), Positives = 144/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T +D AVK+L S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1305 QPEYCPDRLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348 Score = 62.0 bits (149), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 101/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP +L + +C + RPSF ++ ++ + Sbjct 1295 VYLLQGRRLLQPEYCPDRLYEVMLKCWHPKAEMRPSFSELVSRISAI 1341 >sp|P33497|RYK_AVIR3 Tyrosine-protein kinase transforming protein RYK OS=Avian retrovirus RPL30 OX=31671 GN=V-RYK PE=2 SV=1 Length=442 Score = 138 bits (347), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 95/288 (33%), Positives = 143/288 (50%), Gaps = 29/288 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQE 947 V + L + LGEG FG V + +GT + VAVK +K D HR + E Sbjct 38 VVIDRNALSLGKVLGEGEFGSV-MEGRLSQPEGTPQKVAVKTMKLD-NFSHREIEEFLSE 95 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSL---QLVMEYVPLGSLRDYLPRHSIGLA------ 998 ++ H ++IK G C + + + +V+ ++ G L +L R + +A Sbjct 96 AACIKDFDHPNVIKLLGVCIELSSQQIPKPMVVLPFMKYGDLHSFLLRSRLEMAPQFVPL 155 Query 999 -QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 LL F I GM YL ++ ++HRDLAARN +L +D V + DFGL+K + G +YYR Sbjct 156 QMLLKFMVDIALGMEYLSSRQFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQ 214 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 PV W A E L + + SDVW+FGVT++E+ T +P G+ Sbjct 215 GRIAKMPVKWIAIESLADRVYTTKSDVWAFGVTMWEIATR---GMTP------YPGVQNH 265 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + E L G+RL +P+ C E+Y +M +CW E + RPTF L Sbjct 266 E-----IYEYLFHGQRLKKPENCLDELYDIMSSCWRAEPADRPTFSQL 308 Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 81/329 (25%), Positives = 141/329 (43%), Gaps = 51/329 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 +D+ ++ LG+G +V EGRL + G P++ + +K+ Sbjct 40 IDRNALSLGKVLGEGEFGSVMEGRLS-QPEGTPQKVAVK-----------------TMKL 81 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV-----RGPENIMVTEYVEHGPLDVW 698 + SH +I F A+ + H ++ + GVC+ + P+ ++V ++++G L + Sbjct 82 DNFSHREIE-EFLSEAACIKDFDHPNVIKLLGVCIELSSQQIPKPMVVLPFMKYGDLHSF 140 Query 699 LRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L R R VP+ + +A + YL ++ +H ++ RN +L R + + Sbjct 141 LLRSRLEMAPQFVPLQMLLKFMVDIALGMEYLSSRQFLHRDLAARNCML-RDDMTVCVAD 199 Query 754 FIKLSDPGVGLGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 F LS + G R+ R+ ++P W+A E L +T D W FG T+ EI G Sbjct 200 F-GLSKK-IYSGDYYRQGRIAKMPVKWIAIESL--ADRVYTTKSDVWAFGVTMWEIATRG 255 Query 812 EAPLQSRSPSEKEH------FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 P P + H F+ ++ + PE +L + S C EP RP+F + Sbjct 256 MTPY----PGVQNHEIYEYLFHGQRLKKPENCLDELYDIMSSCWRAEPADRPTFSQLKVH 311 Query 866 LTRL-----QPHNLADVLTVNPDSPASDP 889 L +L P DV+ VN P P Sbjct 312 LEKLLESLPAPRGSKDVIYVNTSLPEESP 340 >sp|Q02858|TIE2_MOUSE Angiopoietin-1 receptor OS=Mus musculus OX=10090 GN=Tek PE=1 SV=2 Length=1122 Score = 143 bits (361), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 102/309 (33%), Positives = 148/309 (48%), Gaps = 43/309 (14%) Query 888 DPTVFHKRYLKKIR---DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 DPT++ I+ +GEG+FG+V DG A+K +K + Sbjct 810 DPTIYPVLDWNDIKFQDVIGEGNFGQV--LKARIKKDGLRMDAAIKRMKEYASKDDHRDF 867 Query 945 KQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---------- 993 E+++L L +H +II G CE +G L L +EY P G+L D+L + Sbjct 868 AGELEVLCKLGHHPNIINLLGACEHRG--YLYLAIEYAPHGNLLDFLRKSRVLETDPAFA 925 Query 994 -------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 ++ QLL FA + GM YL + +IHRDLAARN+L+ + + KI DFGL++ Sbjct 926 IANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYIAKIADFGLSR 985 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 G E Y + G PV W A E L + SDVWS+GV L+E+++ Sbjct 986 ----GQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVS---------- 1031 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L G MT L E L +G RL +P C EVY LM+ CW + RP+F ++ Sbjct 1032 ----LGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQIL 1087 Query 1167 PILKTVHEK 1175 L + E+ Sbjct 1088 VSLNRMLEE 1096 Score = 65.1 bits (157), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 79/335 (24%), Positives = 135/335 (40%), Gaps = 58/335 (17%) Query 557 ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD- 615 + L + R A+ +P L ++ + +++ + GQ + + + LR++ + Sbjct 795 NSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKR 854 Query 616 -PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 E DD RD EL V+ K+ HH ++ + Sbjct 855 MKEYASKDDH------RDFAGELEVLCKL---GHH------------------PNIINLL 887 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRER--------GHVPMAWKMVVAQQL-------A 719 G C + EY HG L +LR+ R + +QQL A Sbjct 888 GACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVA 947 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA-LSREERVERIP- 777 + YL K +H ++ RNIL+ G + K++D G+ G + ++ + R+P Sbjct 948 RGMDYLSQKQFIHRDLAARNILV-------GENYIAKIADFGLSRGQEVYVKKTMGRLPV 1000 Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836 W+A E L + +T D W +G L EI G P + +E + +RL +P Sbjct 1001 RWMAIESL--NYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKP 1058 Query 837 -SC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 +C ++ L QC +P +RPSF IL L R+ Sbjct 1059 LNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRM 1093 >sp|P16277|BLK_MOUSE Tyrosine-protein kinase Blk OS=Mus musculus OX=10090 GN=Blk PE=1 SV=4 Length=499 Score = 139 bits (350), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 93/298 (31%), Positives = 143/298 (48%), Gaps = 31/298 (10%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 A D ++ LK +R LG G FG+V + Y VA+K LK G + Sbjct 224 AQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYK-----NNMKVAIKTLKE--GTMSPEAFL 276 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLL 1002 E ++++TL HE +++ + + +V EY+ G L D+L + L +L+ Sbjct 277 GEANVMKTLQHERLVRLYAVVTRE---PIYIVTEYMARGCLLDFLKTDEGSRLSLPRLID 333 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 + Q+ EGMAY+ + IHRDL A N+L+ KI DFGLA+ + Y +E Sbjct 334 MSAQVAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARII---DSEYTAQEGAK 390 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 P+ W APE + F +DVWSFGV L E++T+ + M+ Sbjct 391 FPIKWTAPEAIHFGVFTIKADVWSFGVLLMEIVTYGR--------------VPYPGMSNP 436 Query 1123 RLTELLERGERLPRPDKCPCEVYH-LMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 + LE G R+P P+ CP E+Y+ ++ CW RPTFE L +L+ + +GQ Sbjct 437 EVIRSLEHGYRMPCPETCPPELYNDIITECWRGRPEERPTFEFLQSVLEDFYTATEGQ 494 Score = 72.0 bits (175), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 61/226 (27%), Positives = 105/226 (46%), Gaps = 25/226 (11%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKM 712 AF A++M + H L ++ V R P I VTEY+ G L +L+ + G + + + Sbjct 274 AFLGEANVMKTLQHERLVRLYAVVTREPIYI-VTEYMARGCLLDFLKTDEGSRLSLPRLI 332 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 ++ Q+A ++Y+E N +H ++ NIL++ + K++D GL + E Sbjct 333 DMSAQVAEGMAYIERMNSIHRDLRAANILVSE-------TLCCKIAD--FGLARIIDSEY 383 Query 773 VER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + I W APE + G ++ D W FG L+EI G P S E Sbjct 384 TAQEGAKFPIKWTAPEAIHFGVFTIKA--DVWSFGVLLMEIVTYGRVPYPGMSNPEVIRS 441 Query 827 YQRQHRLPEP-SCPQ--LATLTSQCLTYEPTQRPSF---RTILRDL 866 + +R+P P +CP + ++C P +RP+F +++L D Sbjct 442 LEHGYRMPCPETCPPELYNDIITECWRGRPEERPTFEFLQSVLEDF 487 >sp|Q06807|TIE2_BOVIN Angiopoietin-1 receptor OS=Bos taurus OX=9913 GN=TEK PE=2 SV=1 Length=1125 Score = 143 bits (361), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 102/309 (33%), Positives = 148/309 (48%), Gaps = 43/309 (14%) Query 888 DPTVFHKRYLKKIR---DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 DPT++ I+ +GEG+FG+V DG A+K +K + Sbjct 813 DPTIYPVLDWNDIKFQDVIGEGNFGQV--LKARIKKDGLRMDAAIKRMKEYASKDDHRDF 870 Query 945 KQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---------- 993 E+++L L +H +II G CE +G L L +EY P G+L D+L + Sbjct 871 AGELEVLCKLGHHPNIINLLGACEHRG--YLYLAIEYAPHGNLLDFLRKSRVLETDPAFA 928 Query 994 -------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 ++ QLL FA + GM YL + +IHRDLAARN+L+ + + KI DFGL++ Sbjct 929 IANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSR 988 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 G E Y + G PV W A E L + SDVWS+GV L+E+++ Sbjct 989 ----GQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVS---------- 1034 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L G MT L E L +G RL +P C EVY LM+ CW + RP+F ++ Sbjct 1035 ----LGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQIL 1090 Query 1167 PILKTVHEK 1175 L + E+ Sbjct 1091 VSLNRMLEE 1099 Score = 64.3 bits (155), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 79/335 (24%), Positives = 135/335 (40%), Gaps = 58/335 (17%) Query 557 ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD- 615 + L + R A+ +P L ++ + +++ + GQ + + + LR++ + Sbjct 798 NSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKR 857 Query 616 -PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 E DD RD EL V+ K+ HH +L+ H + Sbjct 858 MKEYASKDDH------RDFAGELEVLCKL---GHHP------NIINLLGACEHRGYLY-- 900 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRER--------GHVPMAWKMVVAQQL-------A 719 + EY HG L +LR+ R + +QQL A Sbjct 901 ----------LAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVA 950 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA-LSREERVERIP- 777 + YL K +H ++ RNIL+ G + K++D G+ G + ++ + R+P Sbjct 951 RGMDYLSQKQFIHRDLAARNILV-------GENYVAKIADFGLSRGQEVYVKKTMGRLPV 1003 Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836 W+A E L + +T D W +G L EI G P + +E + +RL +P Sbjct 1004 RWMAIESL--NYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKP 1061 Query 837 -SC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 +C ++ L QC +P +RPSF IL L R+ Sbjct 1062 LNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRM 1096 >sp|Q06806|TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mus musculus OX=10090 GN=Tie1 PE=1 SV=3 Length=1134 Score = 143 bits (361), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 99/281 (35%), Positives = 134/281 (48%), Gaps = 40/281 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961 +GEG+FG+V DG A+K LK + E+++L L +H +II Sbjct 841 IGEGNFGQVIRAMIK--KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIIN 898 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-----------GLA------QLLLFA 1004 G CE++G L + +EY P G+L D+L + + G A QLL FA Sbjct 899 LLGACENRG--YLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFA 956 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 GM YL + +IHRDLAARNVL+ + KI DFGL++ G E Y + G P Sbjct 957 SDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSR----GEEVYVKKTMGRLP 1012 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 V W A E L + SDVWSFGV L+E+++ L G MT L Sbjct 1013 VRWMAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCGMTCAEL 1058 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 E L +G R+ +P C EVY LM+ CW RP F + Sbjct 1059 YEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQI 1099 Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 71/332 (21%), Positives = 129/332 (39%), Gaps = 54/332 (16%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 + L + R + P L+ L + + +++ + GQ R + + L++ + Sbjct 809 SGTLTLTRRPKPQPEPLSYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKML 868 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 + + D RD EL V+ K+ HH ++ + G C Sbjct 869 KEYASEND----HRDFAGELEVLCKL---GHH------------------PNIINLLGAC 903 Query 678 VRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLASAL 722 + EY +G L +LR+ R + + A A+ + Sbjct 904 ENRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGM 963 Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP--WL 779 YL K +H ++ RN+L+ G + K++D G+ G + ++ + R+P W+ Sbjct 964 QYLSEKQFIHRDLAARNVLV-------GENLASKIADFGLSRGEEVYVKKTMGRLPVRWM 1016 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838 A E L + +T D W FG L EI G P + +E + +R+ +P +C Sbjct 1017 AIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNC 1074 Query 839 -PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 ++ L QC P +RP F I L R+ Sbjct 1075 DDEVYELMRQCWRDRPYERPPFAQIALQLGRM 1106 >sp|P21709|EPHA1_HUMAN Ephrin type-A receptor 1 OS=Homo sapiens OX=9606 GN=EPHA1 PE=1 SV=4 Length=976 Score = 143 bits (360), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 88/266 (33%), Positives = 134/266 (50%), Gaps = 22/266 (8%) Query 903 LGEGHFGKVSLYCYD-PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG FG+V P+ D + VA+K LK + +E I+ H HI+ Sbjct 630 IGEGEFGEVYRGTLRLPSQDC--KTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 687 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHY 1019 +G + K + ++ E++ G+L +L L QL+ Q I GM YL +Y Sbjct 688 LEGVVTKR--KPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNY 745 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDLAARN+L++ + K+ DFGL + + + Y + G P+ W APE + F Sbjct 746 VHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYET-QGGKIPIRWTAPEAIAHRIFT 804 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 ASDVWSFG+ ++E+L+ D G+M+ + + +E G RLP P Sbjct 805 TASDVWSFGIVMWEVLSFGDK--------------PYGEMSNQEVMKSIEDGYRLPPPVD 850 Query 1140 CPCEVYHLMKNCWETEASFRPTFENL 1165 CP +Y LMKNCW + + RP F+ L Sbjct 851 CPAPLYELMKNCWAYDRARRPHFQKL 876 Score = 101 bits (252), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 73/236 (31%), Positives = 114/236 (48%), Gaps = 15/236 (6%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F A++M Q SH H+ + GV + +++TE++E+G LD +LR + + + Sbjct 670 FLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAM 729 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF--IKLSDPGVGLGALSREER 772 Q +AS ++YL N N VH ++ RNIL+ + L S F +L D G + E + Sbjct 730 LQGIASGMNYLSNHNYVHRDLAARNILVNQ-NLCCKVSDFGLTRLLDDFDG----TYETQ 784 Query 773 VERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 +IP W APE + +TA D W FG + E+ G+ P S E + Sbjct 785 GGKIPIRWTAPEAI--AHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDG 842 Query 831 HRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVLTVNP 882 +RLP P CP L L C Y+ +RP F+ + L +L PH+L + +P Sbjct 843 YRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRTIANFDP 898 >sp|Q02763|TIE2_HUMAN Angiopoietin-1 receptor OS=Homo sapiens OX=9606 GN=TEK PE=1 SV=2 Length=1124 Score = 143 bits (360), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 102/309 (33%), Positives = 148/309 (48%), Gaps = 43/309 (14%) Query 888 DPTVFHKRYLKKIR---DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 DPT++ I+ +GEG+FG+V DG A+K +K + Sbjct 812 DPTIYPVLDWNDIKFQDVIGEGNFGQV--LKARIKKDGLRMDAAIKRMKEYASKDDHRDF 869 Query 945 KQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---------- 993 E+++L L +H +II G CE +G L L +EY P G+L D+L + Sbjct 870 AGELEVLCKLGHHPNIINLLGACEHRG--YLYLAIEYAPHGNLLDFLRKSRVLETDPAFA 927 Query 994 -------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 ++ QLL FA + GM YL + +IHRDLAARN+L+ + + KI DFGL++ Sbjct 928 IANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSR 987 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 G E Y + G PV W A E L + SDVWS+GV L+E+++ Sbjct 988 ----GQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVS---------- 1033 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L G MT L E L +G RL +P C EVY LM+ CW + RP+F ++ Sbjct 1034 ----LGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQIL 1089 Query 1167 PILKTVHEK 1175 L + E+ Sbjct 1090 VSLNRMLEE 1098 Score = 63.5 bits (153), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 76/307 (25%), Positives = 125/307 (41%), Gaps = 51/307 (17%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEG-SGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 +D +I +G+G V + R++ +G D +M + RD EL V+ K Sbjct 819 LDWNDIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCK 878 Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 + HH +L+ H + + EY HG L +LR+ Sbjct 879 L---GHHP------NIINLLGACEHRGYLY------------LAIEYAPHGNLLDFLRKS 917 Query 703 R--------GHVPMAWKMVVAQQL-------ASALSYLENKNLVHGNVCGRNILLARLGL 747 R + +QQL A + YL K +H ++ RNIL+ Sbjct 918 RVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILV----- 972 Query 748 AEGTSPFIKLSDPGVGLGA-LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATL 804 G + K++D G+ G + ++ + R+P W+A E L + +T D W +G L Sbjct 973 --GENYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESL--NYSVYTTNSDVWSYGVLL 1028 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEPTQRPSFRTI 862 EI G P + +E + +RL +P +C ++ L QC +P +RPSF I Sbjct 1029 WEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQI 1088 Query 863 LRDLTRL 869 L L R+ Sbjct 1089 LVSLNRM 1095 >sp|Q10656|EGL15_CAEEL Myoblast growth factor receptor egl-15 OS=Caenorhabditis elegans OX=6239 GN=egl-15 PE=1 SV=1 Length=1040 Score = 143 bits (360), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 101/318 (32%), Positives = 151/318 (47%), Gaps = 53/318 (17%) Query 887 SDPT-VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 SDP + L + LGEG FG+V Y T + VAVK LK + Sbjct 629 SDPVWEVERSKLSLVHMLGEGAFGEVWKATYKETENNEI-AVAVKKLKMSAHEKELIDLV 687 Query 946 QEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----------- 993 E++ + + HE++++ GCC G L +V+E G+LRD+L H Sbjct 688 SEMETFKVIGEHENVLRLIGCC--TGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSS 745 Query 994 ----------------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031 ++ L+ FA Q+ +GM +L ++ IHRDLAARNVL+ Sbjct 746 QELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLV 805 Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091 + ++KI DFGL++ V ++YYR R +G P+ W A E L + SDVWS+GV L Sbjct 806 GDGHVLKISDFGLSRDV-HCNDYYRKRGNGRLPIKWMALEALDSNVYTVESDVWSYGVLL 864 Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 +E++T L G + + L L+ G R+ P CP EVYHLM +C Sbjct 865 WEIMT--------------LGGTPYPTIAMPELYANLKEGYRMEPPHLCPQEVYHLMCSC 910 Query 1152 WETEASFRPTFENLIPIL 1169 W + RP+F+ ++ L Sbjct 911 WREKLEERPSFKTIVDYL 928 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 46/170 (27%), Positives = 77/170 (45%), Gaps = 23/170 (14%) Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 +R V AW Q+A +++L +K ++H ++ RN+L+ G +K+SD G Sbjct 771 QRHLVQFAW------QVAQGMNFLASKKIIHRDLAARNVLV-------GDGHVLKISDFG 817 Query 762 VGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 + + +R I W+A E L +N + D W +G L EI G P Sbjct 818 LSRDVHCNDYYRKRGNGRLPIKWMALEAL--DSNVYTVESDVWSYGVLLWEIMTLGGTPY 875 Query 816 QSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTIL 863 + + E + +R+ P CPQ + L C + +RPSF+TI+ Sbjct 876 PTIAMPELYANLKEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIV 925 >sp|O76997|TRK1_LYMST Putative neurotrophin receptor LTRK 1 OS=Lymnaea stagnalis OX=6523 PE=2 SV=1 Length=794 Score = 142 bits (358), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 91/291 (31%), Positives = 141/291 (48%), Gaps = 37/291 (13%) Query 900 IRDLGEGHFGKVSL-YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 +R +GEG FG+V L C +VAVK LK C + +++E ++L T+ H + Sbjct 507 MRVIGEGAFGRVFLGTCAHLIQKNEFAIVAVKTLKGSCSDSLKRDFEREAEMLATIEHAN 566 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA------------------QL 1000 I+ + G C + + ++ E++ G L YL H A QL Sbjct 567 IVTFYGVCTESDQ--WMMIFEFMENGDLNKYLRMHGPDAAFLKDRDSMDSDEGQLTREQL 624 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 + QI M YL QH++HRDLA RN L+ D +VK+GDFG+++ V +YYRV Sbjct 625 MKIVLQIASAMEYLALQHFVHRDLATRNCLVGCDLVVKLGDFGMSRDV-YTTDYYRVEGT 683 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 PV W PE + F SDVWSFGVTL+E+ T+ + P ++ + Sbjct 684 AMLPVRWMPPESIIYRTFTTESDVWSFGVTLWEVFTY---GKQPWFEY-----------S 729 Query 1121 VLRLTELLERGERLPRPDK-CPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + E ++ L RP + C VY +M+ CW+ R T +++ +L+ Sbjct 730 NSEVIEHIKNSRTLKRPPRTCTDGVYRVMQGCWKPNPQDRLTMKDIAELLR 780 Score = 71.2 bits (173), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 57/221 (26%), Positives = 95/221 (43%), Gaps = 32/221 (14%) Query 639 VVLKVLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V +K L S D + F A +++ + H ++ +GVC + +M+ E++E+G L+ Sbjct 535 VAVKTLKGSCSDSLKRDFEREAEMLATIEHANIVTFYGVCTESDQWMMIFEFMENGDLNK 594 Query 698 WLR----------------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 +LR + G + M + Q+ASA+ YL ++ VH ++ RN L Sbjct 595 YLRMHGPDAAFLKDRDSMDSDEGQLTREQLMKIVLQIASAMEYLALQHFVHRDLATRNCL 654 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGANSLSTAM 795 + G +KL D G+ + R E +P W+ PE + + +T Sbjct 655 V-------GCDLVVKLGDFGMSRDVYTTDYYRVEGTAMLPVRWMPPESII--YRTFTTES 705 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836 D W FG TL E+ G+ P S SE + L P Sbjct 706 DVWSFGVTLWEVFTYGKQPWFEYSNSEVIEHIKNSRTLKRP 746 >sp|Q9PVZ4|INSR_XENLA Insulin receptor OS=Xenopus laevis OX=8355 GN=insr PE=1 SV=1 Length=1362 Score = 143 bits (361), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 92/283 (33%), Positives = 147/283 (52%), Gaps = 29/283 (10%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 +R+LG+G FG V G E+ VAVK + + R + E +++ H Sbjct 1015 LRELGQGSFGMVYEGIAKDIIKGEPEVRVAVKTVNESASLRERIEFLNEASVMKAFNCHH 1074 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------PRHSIGLAQLLLFAQQI 1007 +++ G +G+ +L ++ME + G L+ YL R + L +++ A +I Sbjct 1075 VVRLLGVVS-KGQPTL-VIMELMAHGDLKSYLRSLRPDAENNPGRLAPTLKEIIQMAAEI 1132 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 +GMAYL+A+ ++HRDLAARN ++ +D VKIGDFG+ + + E +YYR G PV W Sbjct 1133 SDGMAYLNAKKFVHRDLAARNCMVADDYAVKIGDFGMTRDIYET-DYYRKGGKGLLPVRW 1191 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 +PE LK+ F SDVWSFGV L+E+ + + G++ Q + + Sbjct 1192 MSPESLKDGVFTAFSDVWSFGVVLWEITSLAEQPYQ---------GLSNEQ-----VLKF 1237 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + G L P+ CP ++ LM+ CW+ RPTF +I +LK Sbjct 1238 VMDGGSLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLK 1280 Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 77/298 (26%), Positives = 124/298 (42%), Gaps = 46/298 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V + +I L LGQG+ VYEG + G+PE +RV +K Sbjct 1007 VPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPE-------------------VRVAVKT 1047 Query 644 LDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 ++ S + F AS+M + H+ + GV +G +++ E + HG L +LR Sbjct 1048 VNESASLRERIEFLNEASVMKAFNCHHVVRLLGVVSKGQPTLVIMELMAHGDLKSYLRSL 1107 Query 703 R-------GHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 R G + K ++ A +++ ++YL K VH ++ RN ++A Sbjct 1108 RPDAENNPGRLAPTLKEIIQMAAEISDGMAYLNAKKFVHRDLAARNCMVA-------DDY 1160 Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+ D G+ + + + + W++PE L G + D W FG L EI Sbjct 1161 AVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTAFSDVWSFGVVLWEI 1218 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 E P Q S + F L PE P+L +L C Y P RP+F I+ Sbjct 1219 TSLAEQPYQGLSNEQVLKFVMDGGSLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEII 1276 >sp|O15146|MUSK_HUMAN Muscle, skeletal receptor tyrosine-protein kinase OS=Homo sapiens OX=9606 GN=MUSK PE=1 SV=1 Length=869 Score = 142 bits (358), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 90/318 (28%), Positives = 156/318 (49%), Gaps = 53/318 (17%) Query 892 FHKRYLKKIRDLGEGHFGKV------SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 + + ++ +RD+GEG FG+V L Y+P MVAVK LK + ++ ++ Sbjct 570 YPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFT-----MVAVKMLKEEASADMQADFQ 624 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------- 994 +E ++ + +I+K G C K + L+ EY+ G L ++L S Sbjct 625 REAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSD 682 Query 995 --------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040 + A+ L A+Q+ GMAYL + ++HRDLA RN L+ + +VKI Sbjct 683 LSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIA 742 Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100 DFGL++ + +YY+ E+ P+ W PE + ++ SDVW++GV L+E+ ++ Sbjct 743 DFGLSRNIYSA-DYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSY--- 798 Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 G+A ++ + G L P+ CP E+Y+LM+ CW + RP Sbjct 799 ------GLQPYYGMAHEEVIY-----YVRDGNILSCPENCPVELYNLMRLCWSKLPADRP 847 Query 1161 TFENLIPILKTVHEKYQG 1178 +F ++ IL+ + E+ +G Sbjct 848 SFTSIHRILERMCERAEG 865 Score = 77.8 bits (190), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 67/263 (25%), Positives = 117/263 (44%), Gaps = 41/263 (16%) Query 639 VVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V +K+L + + D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+ Sbjct 606 VAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNE 665 Query 698 WLRRERGH-----------------------VPMAWKMVVAQQLASALSYLENKNLVHGN 734 +LR H + A ++ +A+Q+A+ ++YL + VH + Sbjct 666 FLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRD 725 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGA 788 + RN L+ G + +K++D G+ S E I W+ PE + Sbjct 726 LATRNCLV-------GENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESI--FY 776 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTS 846 N +T D W +G L EI G P + E ++ + + L P +CP +L L Sbjct 777 NRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMR 836 Query 847 QCLTYEPTQRPSFRTILRDLTRL 869 C + P RPSF +I R L R+ Sbjct 837 LCWSKLPADRPSFTSIHRILERM 859 >sp|Q07E37|MET_NEONE Hepatocyte growth factor receptor OS=Neofelis nebulosa OX=61452 GN=MET PE=3 SV=1 Length=1382 Score = 143 bits (360), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 95/284 (33%), Positives = 144/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T +D AVK+L S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348 Score = 60.8 bits (146), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1341 >sp|A0M8S8|MET_FELCA Hepatocyte growth factor receptor OS=Felis catus OX=9685 GN=MET PE=3 SV=1 Length=1382 Score = 143 bits (360), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 95/284 (33%), Positives = 144/284 (51%), Gaps = 27/284 (10%) Query 903 LGEGHFGKVSLYCYDPT---NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G GHFG V Y T +D AVK+L S + E I++ H ++ Sbjct 1085 IGRGHFGCV----YHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1140 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL ++ Sbjct 1141 LSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1199 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECLKE 1075 ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L+ Sbjct 1200 KFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESLQT 1258 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF SDVWSFGV L+EL+T +PP + +T L +G RL Sbjct 1259 QKFTTKSDVWSFGVLLWELMTR----GAPPYP----------DVNTFDITVYLLQGRRLL 1304 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1305 QPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348 Score = 60.8 bits (146), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 100/227 (44%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F +M SH ++ + G+C+R + ++V Y++HG L ++R E H P ++ Sbjct 1125 FLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET-HNPTVKDLI 1183 Query 714 -VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+A + YL +K VH ++ RN +L +K++D G+ +E Sbjct 1184 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------KFTVKVADFGLARDMYDKEYY 1236 Query 771 ----ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++P W+A E L +T D W FG L E+ G P + + Sbjct 1237 SVHNKTGAKLPVKWMALESLQ--TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDIT 1294 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + RL +P CP L + +C + RPSF ++ ++ + Sbjct 1295 VYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAI 1341 >sp|O45539|SRC2_CAEEL Tyrosine protein-kinase src-2 OS=Caenorhabditis elegans OX=6239 GN=src-2 PE=1 SV=2 Length=507 Score = 138 bits (348), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 100/307 (33%), Positives = 149/307 (49%), Gaps = 42/307 (14%) Query 875 ADVLTVNPDSP-----ASDPTVF--------HKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 AD L VN +P A T F +R ++ IR +G G FG+V ++ Sbjct 205 ADGLCVNLGAPCAKSEAPQTTTFTYDDQWEVDRRSVRLIRQIGAGQFGEVWEGRWN---- 260 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK-YKGCCEDQGEKSLQLVMEY 980 VAVK LKA G + + E I++ L H ++ Y C D+ L++ Sbjct 261 -VNVPVAVKKLKA--GTADPTDFLAEAQIMKKLRHPKLLSLYAVCTRDEP----ILIVTE 313 Query 981 VPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 + +L +L R + QL+ + Q+ GMAYL ++IHRDLAARN+L++N VK Sbjct 314 LMQENLLTFLQRRGRQCQMPQLVEISAQVAAGMAYLEEMNFIHRDLAARNILINNSLSVK 373 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 I DFGLA+ + + +E Y R P+ W APE +F SDVWSFG+ L E++T Sbjct 374 IADFGLARILMKENE-YEARTGARFPIKWTAPEAANYNRFTTKSDVWSFGILLTEIVT-- 430 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 + MT + + ++ G R+P P CP +Y +M+ CW ++ Sbjct 431 ------------FGRLPYPGMTNAEVLQQVDAGYRMPCPAGCPVTLYDIMQQCWRSDPDK 478 Query 1159 RPTFENL 1165 RPTFE L Sbjct 479 RPTFETL 485 Score = 99.8 bits (247), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 107/415 (26%), Positives = 167/415 (40%), Gaps = 75/415 (18%) Query 467 EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSV 526 E G +L+ S S + L L+V + D ++ R+R+ G F+ R F ++ Sbjct 144 EHGAFLVRDSESRQHDLSLSVREN----DSVKHYRIRQL---DHGGYFIARR--RPFATL 194 Query 527 RELGAALQGCLLRAGDD-CFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVD 585 +L A Q R D C +L C +P+T + VD Sbjct 195 HDLIAHYQ----READGLCVNLGAPC--------------AKSEAPQTTTFTYDDQWEVD 236 Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ + + +G G V+EGR V VP V +K L Sbjct 237 RRSVRLIRQIGAGQFGEVWEGRWNVN----------------VP---------VAVKKLK 271 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 D F A +M ++ H L ++ VC R ++VTE ++ L RR R Sbjct 272 AGTAD-PTDFLAEAQIMKKLRHPKLLSLYAVCTRDEPILIVTELMQENLLTFLQRRGR-Q 329 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 M + ++ Q+A+ ++YLE N +H ++ RNIL+ S +K++D G+ Sbjct 330 CQMPQLVEISAQVAAGMAYLEEMNFIHRDLAARNILI-------NNSLSVKIADFGLARI 382 Query 766 ALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + E R I W APE N +T D W FG L EI G P + Sbjct 383 LMKENEYEARTGARFPIKWTAPEA--ANYNRFTTKSDVWSFGILLTEIVTFGRLPYPGMT 440 Query 820 PSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI---LRDLTRL 869 +E +R+P P+ CP L + QC +P +RP+F T+ L DL L Sbjct 441 NAEVLQQVDAGYRMPCPAGCPVTLYDIMQQCWRSDPDKRPTFETLQWKLEDLFNL 495 >sp|Q95ZV7|DDRB_CAEEL Discoidin domain-containing receptor tyrosine kinase B OS=Caenorhabditis elegans OX=6239 GN=ddr-2 PE=1 SV=1 Length=797 Score = 141 bits (356), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 92/272 (34%), Positives = 146/272 (54%), Gaps = 26/272 (10%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL----KADCGPQHRSGWKQEIDILRTLY 955 + +G+G FG+V L + VAVK L +AD HR EI +L +L Sbjct 530 VSRIGQGEFGEVDLCQLE------NRKVAVKKLHGISQADEFSFHR-----EIRVLGSLK 578 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYL 1014 H ++++ G C Q K + +MEY+ G L+ Y+ ++ +I +Q + Q+ G+AYL Sbjct 579 HPNVVEVVGVCTIQ--KPILCIMEYMENGDLKSYILKNPTIQTSQCISICTQLAAGLAYL 636 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 + +++HRD+AARN L+D + VKI DFG+A+++ EYY+V P+ W A E L Sbjct 637 ESCNFVHRDIAARNCLVDGEGNVKIADFGMARSL-YSQEYYKVEGKFVLPIRWMAWEALL 695 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF ASDVW FGVT++E+ + C +++ Q + L ++L Sbjct 696 LGKFSTASDVWGFGVTMWEIFSLCSEKPYSDMTDDDVVENLQSMSSTGSLKQVLS----- 750 Query 1135 PRPDKCPCEVYH-LMKNCWETEASFRPTFENL 1165 RP CP ++Y+ + CW E+S RP+FEN+ Sbjct 751 -RPRMCPSKLYNEQILPCWNYESSRRPSFENV 781 Score = 77.4 bits (189), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 71/257 (28%), Positives = 115/257 (45%), Gaps = 34/257 (13%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L +F+ ++ + H ++ V GVC + + EY+E+G L Sbjct 550 KVAVKKLHGISQADEFSFHREIRVLGSLKHPNVVEVVGVCTIQKPILCIMEYMENGDLKS 609 Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 ++ + + + + + QLA+ L+YLE+ N VH ++ RN L+ EG +K+ Sbjct 610 YILKNPT-IQTSQCISICTQLAAGLAYLESCNFVHRDIAARNCLVD----GEGN---VKI 661 Query 758 SDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI-CFD 810 +D G+ S+E + V I W+A E L G STA D WGFG T+ EI Sbjct 662 ADFGMARSLYSQEYYKVEGKFVLPIRWMAWEALLLG--KFSTASDVWGFGVTMWEIFSLC 719 Query 811 GEAPLQSRSPSEKEHFYQR-------QHRLPEPS-CPQLATLTSQ----CLTYEPTQRPS 858 E P + + Q + L P CP + L ++ C YE ++RPS Sbjct 720 SEKPYSDMTDDDVVENLQSMSSTGSLKQVLSRPRMCP--SKLYNEQILPCWNYESSRRPS 777 Query 859 FRTI---LRDLTRLQPH 872 F + L+ L PH Sbjct 778 FENVHLHLQSLVHTSPH 794 >sp|Q4H3K6|FGFR_CIOIN Fibroblast growth factor receptor OS=Ciona intestinalis OX=7719 GN=FGFR PE=2 SV=1 Length=747 Score = 140 bits (354), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 98/291 (34%), Positives = 139/291 (48%), Gaps = 41/291 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMV--AVKALKADCGPQHRSGWKQEIDILRTL-YHEHI 959 + EG FG+V G E V AVK LK+ + E+D ++ + H++I Sbjct 383 IDEGFFGQVFRADLIRCAGGRKEKVDAAVKMLKSTRTEKDMLDLLTEMDQMKRVGKHKNI 442 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------------------IGLA 998 + G C G L LV EY G+LRDYL R+ + L Sbjct 443 VNLLGVCTQNG--ILWLVTEYAQKGNLRDYLRRNRPSELQYELSTPDSPAPPRDEPLTLR 500 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 L+ + Q+ GM YL + IHRDLAARNVL+ ND ++KI DFGLA+ + ++YYR Sbjct 501 ALMSASHQVARGMEYLSQKKCIHRDLAARNVLVANDFVMKIADFGLARDI-RSNDYYRKE 559 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 G P W A E + + F +A+DVWSFG+ L+E+ + S P K +L+ Sbjct 560 TRGHLPYKWMALEAMTDNMFTHATDVWSFGILLWEIFS-LGGSPYPGVKTHDLV------ 612 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 L G+RL +P E+Y LM++CWE RP F L+ L Sbjct 613 -------RFLRNGDRLEQPQFASSELYRLMRDCWEESPRRRPQFRQLVEDL 656 Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 67/266 (25%), Positives = 111/266 (42%), Gaps = 38/266 (14%) Query 633 RGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 R +++ +K+L + D+ E + H ++ + GVC + +VTEY Sbjct 403 RKEKVDAAVKMLKSTRTEKDMLDLLTEMDQMKRVGKHKNIVNLLGVCTQNGILWLVTEYA 462 Query 691 EHGPLDVWLRRER-----------------GHVPMAWK--MVVAQQLASALSYLENKNLV 731 + G L +LRR R P+ + M + Q+A + YL K + Sbjct 463 QKGNLRDYLRRNRPSELQYELSTPDSPAPPRDEPLTLRALMSASHQVARGMEYLSQKKCI 522 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLP 785 H ++ RN+L+A +K++D G+ S R+E +P W+A E + Sbjct 523 HRDLAARNVLVA-------NDFVMKIADFGLARDIRSNDYYRKETRGHLPYKWMALEAMT 575 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLAT 843 N + A D W FG L EI G +P + F + RL +P + +L Sbjct 576 D--NMFTHATDVWSFGILLWEIFSLGGSPYPGVKTHDLVRFLRNGDRLEQPQFASSELYR 633 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869 L C P +RP FR ++ DL R+ Sbjct 634 LMRDCWEESPRRRPQFRQLVEDLDRM 659 >sp|F1LM93|YES_RAT Tyrosine-protein kinase Yes OS=Rattus norvegicus OX=10116 GN=Yes1 PE=1 SV=1 Length=541 Score = 138 bits (348), Expect = 8e-33, Method: Compositional matrix adjust. Identities = 104/334 (31%), Positives = 155/334 (46%), Gaps = 42/334 (13%) Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVL---------TVNPDSP--ASDPTVFHKRYLKK 899 Y T R F T+ + + H AD L TV P + A D + L+ Sbjct 220 YYITTRAQFDTLQKLVKHYTEH--ADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRL 277 Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG+V + ++ T VA+K LK G + QE I++ L H+ + Sbjct 278 EVKLGQGCFGEVWMGTWNGTTK-----VAIKTLKP--GTMMPEAFLQEAQIMKKLRHDKL 330 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA 1016 + E+ + +V E++ G L D+L + L QL+ A QI +GMAY+ Sbjct 331 VPLYAVVS---EEPIYIVTEFMSKGILLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIER 387 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +YIHRDL A N+L+ + + KI DFGLA+ + + Y R+ P+ W APE Sbjct 388 MNYIHRDLRAANILVGENLVCKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYG 445 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 +F SDVWSFG+ EL+T + M + E +ERG R+P Sbjct 446 RFTIKSDVWSFGILQTELVTKGR--------------VPYPGMVNREVLEQVERGYRMPC 491 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 P CP ++ LM CW+ + RPTFE + L+ Sbjct 492 PQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 525 Score = 72.8 bits (177), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 63/233 (27%), Positives = 106/233 (45%), Gaps = 19/233 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P + AF + A +M ++ H L ++ V P I VTE++ G L Sbjct 299 KVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYI-VTEFMSKGILLD 356 Query 698 WLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G ++ + + +A Q+A ++Y+E N +H ++ NIL+ G + K Sbjct 357 FLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILV-------GENLVCK 409 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG E+ G Sbjct 410 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILQTELVTKG 467 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 P E +R +R+P P CP+ L L + C +P +RP+F I Sbjct 468 RVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYI 520 >sp|Q95YM9|FGFR_HALRO Fibroblast growth factor receptor OS=Halocynthia roretzi OX=7729 GN=FGFR PE=2 SV=1 Length=763 Score = 140 bits (354), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 101/298 (34%), Positives = 143/298 (48%), Gaps = 48/298 (16%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGE--MVAVKALKADCGPQHRSGWKQEIDILRTL-YH 956 + L EG FG+V N+ E + AVK LK + + E+D ++ + H Sbjct 385 VERLDEGFFGQVFKADLVTCNNTRKEKMVCAVKMLKGNRNEKDVLDLLTEMDQMKRVGKH 444 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR------------------------ 992 ++II G C G L LV+EY G+LRDYL R Sbjct 445 KNIINLLGVCTQNG--PLWLVIEYAAQGNLRDYLRRNRPQNTLCNLVLPSEGRNPDDELP 502 Query 993 --HSIGLAQ--LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 H L Q ++ FA Q+ G+ +L + IHRDLAARNVL+ + ++KI DFGLA+ + Sbjct 503 VPHGDTLTQKDIVSFAFQVARGLEFLAQKKCIHRDLAARNVLVTEELVMKIADFGLARDI 562 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 +YYR G P W A E + + F +A+DVWSFGV L+E+ + S P K Sbjct 563 -RSCDYYRKHTRGHLPYKWMALEAMSDNIFTHATDVWSFGVLLWEIFSLA-GSPYPGIKT 620 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 EL+ + L GERL +P E+Y LM++CWE + S RP F L+ Sbjct 621 HELV-------------KFLRSGERLDKPQYASQEMYRLMRDCWEEDPSKRPNFRTLV 665 Score = 69.3 bits (168), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 69/287 (24%), Positives = 118/287 (41%), Gaps = 45/287 (16%) Query 619 GKMDDEDPLVPGRDRGQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676 G++ D + R +++ +K+L + + D+ E + H ++ + GV Sbjct 394 GQVFKADLVTCNNTRKEKMVCAVKMLKGNRNEKDVLDLLTEMDQMKRVGKHKNIINLLGV 453 Query 677 CVRGPENIMVTEYVEHGPLDVWLRRER-------------GHVP-----------MAWKM 712 C + +V EY G L +LRR R G P + K Sbjct 454 CTQNGPLWLVIEYAAQGNLRDYLRRNRPQNTLCNLVLPSEGRNPDDELPVPHGDTLTQKD 513 Query 713 VV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS-- 768 +V A Q+A L +L K +H ++ RN+L+ +K++D G+ S Sbjct 514 IVSFAFQVARGLEFLAQKKCIHRDLAARNVLVTE-------ELVMKIADFGLARDIRSCD 566 Query 769 --REERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 R+ +P W+A E + N + A D W FG L EI +P E Sbjct 567 YYRKHTRGHLPYKWMALEAM--SDNIFTHATDVWSFGVLLWEIFSLAGSPYPGIKTHELV 624 Query 825 HFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 F + RL +P + ++ L C +P++RP+FRT++ DL R+ Sbjct 625 KFLRSGERLDKPQYASQEMYRLMRDCWEEDPSKRPNFRTLVEDLDRM 671 >sp|Q12866|MERTK_HUMAN Tyrosine-protein kinase Mer OS=Homo sapiens OX=9606 GN=MERTK PE=1 SV=2 Length=999 Score = 141 bits (356), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 97/288 (34%), Positives = 138/288 (48%), Gaps = 29/288 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEI 948 V + L + LGEG FG V + DGT VAVK +K D Q + E Sbjct 580 VVIDRNLLILGKILGEGEFGSV-MEGNLKQEDGTSLKVAVKTMKLDNSSQREIEEFLSEA 638 Query 949 DILRTLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGSLRDYL--------PRHSIGL 997 ++ H ++I+ G C QG +++ ++ G L YL P+H I L Sbjct 639 ACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKH-IPL 697 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 LL F I GM YL ++++HRDLAARN +L +D V + DFGL+K + G +YYR Sbjct 698 QTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQ 756 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 PV W A E L + + SDVW+FGVT++E+ T G+ Sbjct 757 GRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATR---------GMTPYPGVQNH 807 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 +M + L G RL +P+ C E+Y +M +CW T+ RPTF L Sbjct 808 EM-----YDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVL 850 Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 81/306 (26%), Positives = 129/306 (42%), Gaps = 51/306 (17%) Query 606 GRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKV--LDPSHHDIALAFYETASLM 662 G++ EG G EG + ED G L+V +K LD S F A+ M Sbjct 590 GKILGEGEFGSVMEGNLKQED--------GTSLKVAVKTMKLDNSSQREIEEFLSEAACM 641 Query 663 SQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDVWL---RRERG--HVPMAWKM 712 SH ++ + GVC+ P+ +++ ++++G L +L R E G H+P+ + Sbjct 642 KDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKHIPLQTLL 701 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPGVGL 764 +A + YL N+N +H ++ RN +L A GL++ + Sbjct 702 KFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSK-----------KIYS 750 Query 765 GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 G R+ R+ ++P W+A E L ++ D W FG T+ EI G P E Sbjct 751 GDYYRQGRIAKMPVKWIAIESL--ADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHE 808 Query 823 KEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL-----QPHNLA 875 + HRL PE +L + C +P RP+F + L +L N A Sbjct 809 MYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESLPDVRNQA 868 Query 876 DVLTVN 881 DV+ VN Sbjct 869 DVIYVN 874 >sp|O42422|EPHA7_CHICK Ephrin type-A receptor 7 OS=Gallus gallus OX=9031 GN=EPHA7 PE=2 SV=1 Length=993 Score = 141 bits (356), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 88/276 (32%), Positives = 142/276 (51%), Gaps = 21/276 (8%) Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 +K R +G G FG+V S P VA+K LK + R + E I+ Sbjct 628 IKIERVIGAGEFGEVCSGRLKLPGKRDVA--VAIKTLKVGYTEKQRRDFLCEASIMGQFD 685 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAY 1013 H +++ +G K + +V+EY+ G+L +L +H + QL+ + I GM Y Sbjct 686 HPNVVHLEGVVTRG--KPVMIVIEYMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRY 743 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 L Y+HRDLAARN+L++++ + K+ DFGL++ + + E G PV W APE + Sbjct 744 LADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAI 803 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF ASDVWS+G+ ++E++++ + P M+ + + +E G R Sbjct 804 QYRKFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMSNQDVIKAIEEGYR 849 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 LP P CP ++ LM +CW+ E RP FE ++ IL Sbjct 850 LPAPMDCPAGLHQLMLDCWQKERGERPKFEQIVGIL 885 Score = 89.7 bits (221), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 83/294 (28%), Positives = 135/294 (46%), Gaps = 28/294 (10%) Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSH 667 RV G+G E G++ +PG+ +++ V +K L + + F AS+M Q H Sbjct 632 RVIGAG--EFGEVCSGRLKLPGK---RDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDH 686 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 ++ + GV RG ++V EY+E+G LD +LR+ G + + + + +A+ + YL + Sbjct 687 PNVVHLEGVVTRGKPVMIVIEYMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLAD 746 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIP--WLA 780 VH ++ RNIL+ ++ K+SD G+ E V +IP W A Sbjct 747 MGYVHRDLAARNILV-------NSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTA 799 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP 839 PE + ++A D W +G + E+ GE P S + + +RLP P CP Sbjct 800 PEAIQ--YRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCP 857 Query 840 Q-LATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVLTV--NPDSPASD 888 L L C E +RP F I+ L ++ P++L L P SP D Sbjct 858 AGLHQLMLDCWQKERGERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLD 911 >sp|O09127|EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus musculus OX=10090 GN=Epha8 PE=1 SV=2 Length=1004 Score = 141 bits (355), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 90/264 (34%), Positives = 134/264 (51%), Gaps = 19/264 (7%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VA+KALKA + R + E I+ H +II+ +G +G ++ +V EY+ GSL Sbjct 663 VAIKALKAGYTERQRQDFLSEAAIMGQFDHPNIIRLEGVVT-RGRLAM-IVTEYMENGSL 720 Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L H + QL+ + + GM YL YIHRDLAARNVL+D + K+ DFGL Sbjct 721 DAFLRTHDGQFTIVQLVGMLRGVGAGMRYLSDLGYIHRDLAARNVLVDGRLVCKVSDFGL 780 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 ++A+ + E G P+ W APE + F ASDVWSFGV ++E+L + + Sbjct 781 SRALEDDPEAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERP--- 837 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 MT + +E G RLP P CP ++ LM +CW + + RP F + Sbjct 838 -----------YWNMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFAH 886 Query 1165 LIPILKT-VHEKYQGQAPSVFSVC 1187 ++ +L VH +A + S C Sbjct 887 VVSVLDALVHSPESLRATATVSRC 910 Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 86/330 (26%), Positives = 139/330 (42%), Gaps = 54/330 (16%) Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 R R+ R + S++ ++ +G G V GRL+V G D Sbjct 620 RAGRSFTREIEASRIHIEKI----------IGSGESGEVCYGRLQVPGQRD--------- 660 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPEN 683 VP V +K L + + F A++M Q H ++ + GV RG Sbjct 661 ---VP---------VAIKALKAGYTERQRQDFLSEAAIMGQFDHPNIIRLEGVVTRGRLA 708 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL- 742 ++VTEY+E+G LD +LR G + + + + + + + YL + +H ++ RN+L+ Sbjct 709 MIVTEYMENGSLDAFLRTHDGQFTIVQLVGMLRGVGAGMRYLSDLGYIHRDLAARNVLVD 768 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIP--WLAPECLPGGANSLSTAM 795 RL K+SD G+ E +IP W APE + + S+A Sbjct 769 GRL--------VCKVSDFGLSRALEDDPEAAYTTAGGKIPIRWTAPEAI--AFRTFSSAS 818 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEP 853 D W FG + E+ GE P + + + + +RLP P CP+ L L C + Sbjct 819 DVWSFGVVMWEVLAYGERPYWNMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDR 878 Query 854 TQRPSFRTILRDLTRL--QPHNLADVLTVN 881 QRP F ++ L L P +L TV+ Sbjct 879 AQRPRFAHVVSVLDALVHSPESLRATATVS 908 >sp|P25020|SRC_RSVH1 Tyrosine-protein kinase transforming protein Src OS=Rous sarcoma virus (strain H-19) OX=11887 GN=V-SRC PE=1 SV=3 Length=526 Score = 137 bits (346), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 96/301 (32%), Positives = 147/301 (49%), Gaps = 34/301 (11%) Query 872 HNLADVL-TVNPDSP--ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 H L +V T P + A D + L+ LG+G FG+V + ++ T VA Sbjct 239 HRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEAKLGQGCFGEVWMGTWNGTT-----RVA 293 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL D Sbjct 294 IKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVIEYMSKGSLLD 348 Query 989 YLPRHSIG----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L + +G L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 349 FL-KGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ER R+P P +CP ++ LM CW + RPTF+ Sbjct 461 ---------VPYPGMVNREVLDQVERAYRMPCPPECPESLHDLMCQCWRKDPEERPTFKY 511 Query 1165 L 1165 L Sbjct 512 L 512 Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 69/237 (29%), Positives = 109/237 (46%), Gaps = 19/237 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +K L P AF + A +M ++ H L ++ V P I++ EY+ G L Sbjct 291 RVAIKTLKPGTMSPE-AFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVI-EYMSKGSLLD 348 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ E G ++V +A Q+AS ++Y+E N VH ++ NIL+ G + K Sbjct 349 FLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILV-------GENLVCK 401 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 402 VADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELTTKG 459 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866 P E +R +R+P P CP+ L L QC +P +RP+F+ + L Sbjct 460 RVPYPGMVNREVLDQVERAYRMPCPPECPESLHDLMCQCWRKDPEERPTFKYLQAQL 516 >sp|P35590|TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 OS=Homo sapiens OX=9606 GN=TIE1 PE=1 SV=1 Length=1138 Score = 141 bits (356), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 98/281 (35%), Positives = 134/281 (48%), Gaps = 40/281 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961 +GEG+FG+V DG A+K LK + E+++L L +H +II Sbjct 845 IGEGNFGQVIRAMIK--KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIIN 902 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-----------GLA------QLLLFA 1004 G C+++G L + +EY P G+L D+L + + G A QLL FA Sbjct 903 LLGACKNRG--YLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFA 960 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 GM YL + +IHRDLAARNVL+ + KI DFGL++ G E Y + G P Sbjct 961 SDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSR----GEEVYVKKTMGRLP 1016 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 V W A E L + SDVWSFGV L+E+++ L G MT L Sbjct 1017 VRWMAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCGMTCAEL 1062 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 E L +G R+ +P C EVY LM+ CW RP F + Sbjct 1063 YEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQI 1103 Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 71/332 (21%), Positives = 129/332 (39%), Gaps = 54/332 (16%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 + L + R + P L+ L + + +++ + GQ R + + L++ + Sbjct 813 SGTLTLTRRPKLQPEPLSYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKML 872 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 + + D RD EL V+ K+ HH ++ + G C Sbjct 873 KEYASEND----HRDFAGELEVLCKL---GHH------------------PNIINLLGAC 907 Query 678 VRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLASAL 722 + EY +G L +LR+ R + + A A+ + Sbjct 908 KNRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGM 967 Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP--WL 779 YL K +H ++ RN+L+ G + K++D G+ G + ++ + R+P W+ Sbjct 968 QYLSEKQFIHRDLAARNVLV-------GENLASKIADFGLSRGEEVYVKKTMGRLPVRWM 1020 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838 A E L + +T D W FG L EI G P + +E + +R+ +P +C Sbjct 1021 AIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNC 1078 Query 839 -PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 ++ L QC P +RP F I L R+ Sbjct 1079 DDEVYELMRQCWRDRPYERPPFAQIALQLGRM 1110 >sp|P00528|SRC64_DROME Tyrosine-protein kinase Src64B OS=Drosophila melanogaster OX=7227 GN=Src64B PE=1 SV=3 Length=552 Score = 138 bits (347), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 93/275 (34%), Positives = 137/275 (50%), Gaps = 32/275 (12%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 ++ +R LG G+FG+V + + D VAVK L+ G + + QE I++ H Sbjct 284 IQLLRKLGRGNFGEVFYGKWRNSID-----VAVKTLRE--GTMSTAAFLQEAAIMKKFRH 336 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMA 1012 ++ C E+ + +V EY+ GSL D+L R G L+ A Q+ GM Sbjct 337 NRLVALYAVCSQ--EEPIYIVQEYMSKGSLLDFL-REGDGRYLHFEDLIYIATQVASGME 393 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 YL ++ IHRDLAARNVL+ + + KI DFGLA+ + + + Y ++ PV W APE Sbjct 394 YLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIAD--DEYCPKQGSRFPVKWTAPEA 451 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + KF SDVWS+G+ L EL T+ + M + E +ERG Sbjct 452 IIYGKFSIKSDVWSYGILLMELFTYGQ--------------VPYPGMHSREVIENIERGF 497 Query 1133 RLPRPDK--CPCEVYHLMKNCWETEASFRPTFENL 1165 R+P+P P +Y L+ CW+ RPTFE L Sbjct 498 RMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFL 532 Score = 89.0 bits (219), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 100/402 (25%), Positives = 161/402 (40%), Gaps = 67/402 (17%) Query 469 GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRE 528 G +L+ S +P L+V DG + ++ + I+ D ++FPS++ Sbjct 184 GTFLVRPSEHNPNGYSLSVKDWE---DG-RGYHVKHYRIKPLDNGGYYIATNQTFPSLQA 239 Query 529 LGAALQGCLLRAGDDCFSLRRCC-LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587 L A L C L R C PQP +R PR+ Sbjct 240 LVMAYSKNALGL---CHILSRPCPKPQPQMWDLGPELRDKYEIPRS-------------- 282 Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 EI L LG+G V+ G+ R + V +K L Sbjct 283 EIQLLRKLGRGNFGEVFYGKWR-------------------------NSIDVAVKTLREG 317 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HV 706 A AF + A++M + H L ++ VC + +V EY+ G L +LR G ++ Sbjct 318 TMSTA-AFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYL 376 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + +A Q+AS + YLE+K L+H ++ RN+L+ +A K+ D G+ Sbjct 377 HFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVA-------KICDFGLARVI 429 Query 767 LSRE---ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 E ++ R P W APE + G S+ + D W +G L+E+ G+ P Sbjct 430 ADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKS--DVWSYGILLMELFTYGQVPYPGMHSR 487 Query 822 EKEHFYQRQHRLPEPSC----PQLATLTSQCLTYEPTQRPSF 859 E +R R+P+P+ + L QC P +RP+F Sbjct 488 EVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTF 529 >sp|O73798|IGF1R_XENLA Insulin-like growth factor 1 receptor OS=Xenopus laevis OX=8355 GN=igf1r PE=1 SV=1 Length=1358 Score = 141 bits (356), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 92/282 (33%), Positives = 143/282 (51%), Gaps = 29/282 (10%) Query 901 RDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 R+LG+G FG V D VA+K + + R + E +++ H+ Sbjct 999 RELGQGSFGMVYEGIAKGVVKDEAETKVAIKTVNEAASMRERIEFLNEASVMKEFNCHHV 1058 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------PRHSIGLAQLLLFAQQIC 1008 ++ G QG+ +L ++ME + G L+ YL + + L +++ A +I Sbjct 1059 VRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSLRPDTESNSGQPTPSLKKMIQMAGEIA 1116 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +GM+YL+A ++HRDLAARN ++ D VKIGDFG+ + + E +YYR G PV W Sbjct 1117 DGMSYLNANKFVHRDLAARNCMVTEDFTVKIGDFGMTRDIYET-DYYRKGGKGLLPVRWM 1175 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 +PE LK+ F SDVWSFGV L+E+ T + G++ Q VLR + Sbjct 1176 SPESLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQ---------GMSNEQ--VLR---FV 1221 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 G L +PD CP ++ LM+ CW+ RP+F +I +K Sbjct 1222 MEGGLLEKPDNCPDMLFELMRMCWQFNPKMRPSFLEIISSIK 1263 Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 79/302 (26%), Positives = 127/302 (42%), Gaps = 48/302 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +++IT LGQG+ VYEG + G + DE E +V +K Sbjct 990 VPREKITMNRELGQGSFGMVYEGIAK---------GVVKDE----------AETKVAIKT 1030 Query 644 LD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 ++ + + F AS+M + + H+ + GV +G +++ E + G L +LR Sbjct 1031 VNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSL 1090 Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 R P KM+ +A ++A +SYL VH ++ RN ++ T Sbjct 1091 RPDTESNSGQPTPSLKKMIQMAGEIADGMSYLNANKFVHRDLAARNCMV--------TED 1142 Query 754 F-IKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 F +K+ D G+ + + + + W++PE L G +T D W FG L E Sbjct 1143 FTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTNSDVWSFGVVLWE 1200 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILR 864 I E P Q S + F L +P +CP L L C + P RPSF I+ Sbjct 1201 IATLAEQPYQGMSNEQVLRFVMEGGLLEKPDNCPDMLFELMRMCWQFNPKMRPSFLEIIS 1260 Query 865 DL 866 + Sbjct 1261 SI 1262 >sp|Q63474|DDR1_RAT Epithelial discoidin domain-containing receptor 1 OS=Rattus norvegicus OX=10116 GN=Ddr1 PE=2 SV=1 Length=910 Score = 140 bits (354), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 99/309 (32%), Positives = 141/309 (46%), Gaps = 47/309 (15%) Query 892 FHKRYLKKIRDLGEGHFGKVSL-YCYDPTNDGTGE-----------MVAVKALKADCGPQ 939 F + L+ LGEG FG+V L DP + T + +VAVK L+ D Sbjct 602 FPRSRLRFKEKLGEGQFGEVHLCEVEDPQDLVTSDFPISVQKGHPLLVAVKILRPDATKN 661 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------ 993 R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L H Sbjct 662 ARNDFLKEVKIMSRLKDLNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSAHQLENKV 719 Query 994 --------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 +I LL QI GM YL +++HRDLA RN L+ + +KI Sbjct 720 TQGLPGDRESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKI 779 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+L C Sbjct 780 ADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCR 838 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER---LPRPDKCPCEVYHLMKNCWETEA 1156 S + G + + E R L RP CP +Y LM CW E Sbjct 839 S---------QPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQTLYELMLRCWSREP 889 Query 1157 SFRPTFENL 1165 RP F L Sbjct 890 EQRPPFSQL 898 Score = 80.1 bits (196), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 77/270 (29%), Positives = 122/270 (45%), Gaps = 44/270 (16%) Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +G L V +K+L P A F + +MS++ ++ + GVCV+ M+T+Y+E Sbjct 643 KGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDLNIIRLLGVCVQDDPLCMITDYME 702 Query 692 HGPLDVWLR---------------RERGHVP-MAWKMV--VAQQLASALSYLENKNLVHG 733 +G L+ +L RE P +++ M+ V Q+AS + YL N VH Sbjct 703 NGDLNQFLSAHQLENKVTQGLPGDRESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHR 762 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGG 787 ++ RN L+ G + IK++D G+ + + V I W+A EC+ G Sbjct 763 DLATRNCLV-------GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG 815 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-----EHFYQRQHRLP----EPSC 838 +TA D W FG TL E+ + + E+ F++ Q R P+C Sbjct 816 --KFTTASDVWAFGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPAC 873 Query 839 PQ-LATLTSQCLTYEPTQRPSFRTILRDLT 867 PQ L L +C + EP QRP F + R L Sbjct 874 PQTLYELMLRCWSREPEQRPPFSQLHRFLA 903 >sp|P08069|IGF1R_HUMAN Insulin-like growth factor 1 receptor OS=Homo sapiens OX=9606 GN=IGF1R PE=1 SV=1 Length=1367 Score = 141 bits (356), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 95/286 (33%), Positives = 146/286 (51%), Gaps = 37/286 (13%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGE-----MVAVKALKADCGPQHRSGWKQEIDILRTLY 955 R+LG+G FG V Y+ G + VA+K + + R + E +++ Sbjct 1003 RELGQGSFGMV----YEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFN 1058 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIG-------LAQLLLFA 1004 H+++ G QG+ +L ++ME + G L+ YL P L++++ A Sbjct 1059 CHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMA 1116 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 +I +GMAYL+A ++HRDLAARN ++ D VKIGDFG+ + + E +YYR G P Sbjct 1117 GEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYE-TDYYRKGGKGLLP 1175 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 V W +PE LK+ F SDVWSFGV L+E+ T + G++ Q VLR Sbjct 1176 VRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQ---------GLSNEQ--VLR- 1223 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + G L +PD CP ++ LM+ CW+ RP+F +I +K Sbjct 1224 --FVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK 1267 Score = 84.3 bits (207), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 79/301 (26%), Positives = 127/301 (42%), Gaps = 46/301 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +++IT LGQG+ VYEG + G + DE E RV +K Sbjct 994 VAREKITMSRELGQGSFGMVYEGVAK---------GVVKDE----------PETRVAIKT 1034 Query 644 LD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 ++ + + F AS+M + + H+ + GV +G +++ E + G L +LR Sbjct 1035 VNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSL 1094 Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 R + P KM+ +A ++A ++YL VH ++ RN ++A Sbjct 1095 RPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAE-------DF 1147 Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+ D G+ + + + + W++PE L G +T D W FG L EI Sbjct 1148 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTYSDVWSFGVVLWEI 1205 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRD 865 E P Q S + F L +P +CP L L C Y P RPSF I+ Sbjct 1206 ATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISS 1265 Query 866 L 866 + Sbjct 1266 I 1266 >sp|Q13308|PTK7_HUMAN Inactive tyrosine-protein kinase 7 OS=Homo sapiens OX=9606 GN=PTK7 PE=1 SV=2 Length=1070 Score = 141 bits (355), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 101/353 (29%), Positives = 162/353 (46%), Gaps = 35/353 (10%) Query 828 QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 +R + PE P++ +CL P Q +++ L T N S Sbjct 733 KRLQKQPEGEEPEM-----ECLNGGPLQNGQPSAEIQEEVALTSLGSGPAAT-NKRHSTS 786 Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE-MVAVKALKADCGPQHRSGWKQ 946 D F + L+ I LG+ FG+V L +G E +V VK+L++ Q + +++ Sbjct 787 DKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSK-DEQQQLDFRR 845 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIG 996 E+++ L H ++++ G C + + +V+EYV LG L+ +L + Sbjct 846 ELEMFGKLNHANVVRLLGLCRE--AEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLS 903 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 Q + Q+ GM +L ++H+DLAARN L+ R VK+ GL+K V EYY Sbjct 904 TKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDV-YNSEYYH 962 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 R+ P+ W +PE + E F SDVW+FGV ++E+ TH + Sbjct 963 FRQ-AWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHG------------- 1008 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 GQ L +L RLP+P+ CP ++Y LM+ CW RP+F + L Sbjct 1009 GQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 1061 Score = 77.0 bits (188), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 69/247 (28%), Positives = 108/247 (44%), Gaps = 25/247 (10%) Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 E V++K L L F + +++H ++ + G+C + MV EYV+ G L Sbjct 824 ETLVLVKSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDL 883 Query 696 DVWLRRERGH------VPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILLARLGL 747 +LR + P++ K VA Q+A + +L N VH ++ RN L++ Sbjct 884 KQFLRISKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVS---- 939 Query 748 AEGTSPFIKLSDPGVGLGALSREE---RVERIP--WLAPECLPGGANSLSTAMDKWGFGA 802 +K+S G+ + E R +P W++PE + G ST D W FG Sbjct 940 ---AQRQVKVSALGLSKDVYNSEYYHFRQAWVPLRWMSPEAILEG--DFSTKSDVWAFGV 994 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQR-QHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 + E+ GE P ++ E Q + RLP+P CP +L L +C P RPSF Sbjct 995 LMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSF 1054 Query 860 RTILRDL 866 I L Sbjct 1055 SEIASAL 1061 >sp|P24062|IGF1R_RAT Insulin-like growth factor 1 receptor OS=Rattus norvegicus OX=10116 GN=Igf1r PE=2 SV=2 Length=1370 Score = 141 bits (355), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 96/290 (33%), Positives = 148/290 (51%), Gaps = 37/290 (13%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGE-----MVAVKALKADCGPQHRSGWKQEIDILRTLY 955 R+LG+G FG V Y+ G + VA+K + + R + E +++ Sbjct 1004 RELGQGSFGMV----YEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFN 1059 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSI---------GLAQLLLFA 1004 H+++ G QG+ +L ++ME + G L+ YL R + L++++ A Sbjct 1060 CHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSLRPEVENNLVLIPPSLSKMIQMA 1117 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 +I +GMAYL+A ++HRDLAARN ++ D VKIGDFG+ + + E +YYR G P Sbjct 1118 GEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYE-TDYYRKGGKGLLP 1176 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 V W +PE LK+ F SDVWSFGV L+E+ T + G++ Q VLR Sbjct 1177 VRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQ---------GLSNEQ--VLR- 1224 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + G L +PD CP ++ LM+ CW+ RP+F +I +K E Sbjct 1225 --FVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEME 1272 Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 80/298 (27%), Positives = 126/298 (42%), Gaps = 46/298 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +++IT LGQG+ VYEG + G + DE E RV +K Sbjct 995 VAREKITMNRELGQGSFGMVYEGVAK---------GVVKDE----------PETRVAIKT 1035 Query 644 LD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 ++ + + F AS+M + + H+ + GV +G +++ E + G L +LR Sbjct 1036 VNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSL 1095 Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 R V P KM+ +A ++A ++YL VH ++ RN ++A Sbjct 1096 RPEVENNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAE-------DF 1148 Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+ D G+ + + + + W++PE L G +T D W FG L EI Sbjct 1149 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTHSDVWSFGVVLWEI 1206 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTIL 863 E P Q S + F L +P +CP L L C Y P RPSF I+ Sbjct 1207 ATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEII 1264 >sp|Q15375|EPHA7_HUMAN Ephrin type-A receptor 7 OS=Homo sapiens OX=9606 GN=EPHA7 PE=1 SV=3 Length=998 Score = 140 bits (354), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 87/276 (32%), Positives = 143/276 (52%), Gaps = 21/276 (8%) Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 +K R +G G FG+V S P VA+K LK + R + E I+ Sbjct 633 IKIERVIGAGEFGEVCSGRLKLPGKRDVA--VAIKTLKVGYTEKQRRDFLCEASIMGQFD 690 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAY 1013 H +++ +G K + +V+E++ G+L +L +H + QL+ + I GM Y Sbjct 691 HPNVVHLEGVVTRG--KPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRY 748 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 L Y+HRDLAARN+L++++ + K+ DFGL++ + + E G PV W APE + Sbjct 749 LADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAI 808 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF ASDVWS+G+ ++E++++ + P M+ + + +E G R Sbjct 809 QYRKFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMSNQDVIKAIEEGYR 854 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 LP P CP ++ LM +CW+ E + RP FE ++ IL Sbjct 855 LPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGIL 890 Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 82/294 (28%), Positives = 135/294 (46%), Gaps = 28/294 (10%) Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSH 667 RV G+G E G++ +PG+ +++ V +K L + + F AS+M Q H Sbjct 637 RVIGAG--EFGEVCSGRLKLPGK---RDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDH 691 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 ++ + GV RG ++V E++E+G LD +LR+ G + + + + +A+ + YL + Sbjct 692 PNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLAD 751 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIP--WLA 780 VH ++ RNIL+ ++ K+SD G+ E V +IP W A Sbjct 752 MGYVHRDLAARNILV-------NSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTA 804 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP 839 PE + ++A D W +G + E+ GE P S + + +RLP P CP Sbjct 805 PEAIQ--YRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCP 862 Query 840 Q-LATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVLTV--NPDSPASD 888 L L C E +RP F I+ L ++ P++L L P SP D Sbjct 863 AGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLD 916 >sp|P54759|EPHA7_RAT Ephrin type-A receptor 7 OS=Rattus norvegicus OX=10116 GN=Epha7 PE=1 SV=1 Length=998 Score = 140 bits (354), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 87/276 (32%), Positives = 143/276 (52%), Gaps = 21/276 (8%) Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 +K R +G G FG+V S P VA+K LK + R + E I+ Sbjct 633 IKIERVIGAGEFGEVCSGRLKLPGKRDVA--VAIKTLKVGYTEKQRRDFLCEASIMGQFD 690 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAY 1013 H +++ +G K + +V+E++ G+L +L +H + QL+ + I GM Y Sbjct 691 HPNVVHLEGVVTRG--KPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRY 748 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 L Y+HRDLAARN+L++++ + K+ DFGL++ + + E G PV W APE + Sbjct 749 LADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAI 808 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF ASDVWS+G+ ++E++++ + P M+ + + +E G R Sbjct 809 QYRKFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMSNQDVIKAIEEGYR 854 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 LP P CP ++ LM +CW+ E + RP FE ++ IL Sbjct 855 LPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGIL 890 Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 75/271 (28%), Positives = 126/271 (46%), Gaps = 24/271 (9%) Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSH 667 RV G+G E G++ +PG+ +++ V +K L + + F AS+M Q H Sbjct 637 RVIGAG--EFGEVCSGRLKLPGK---RDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDH 691 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 ++ + GV RG ++V E++E+G LD +LR+ G + + + + +A+ + YL + Sbjct 692 PNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLAD 751 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIP--WLA 780 VH ++ RNIL+ ++ K+SD G+ E V +IP W A Sbjct 752 MGYVHRDLAARNILV-------NSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTA 804 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP 839 PE + ++A D W +G + E+ GE P S + + +RLP P CP Sbjct 805 PEAIQ--YRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCP 862 Query 840 Q-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 L L C E +RP F I+ L ++ Sbjct 863 AGLHQLMLDCWQKERAERPKFEQIVGILDKM 893 >sp|Q9VBW3|CAD96_DROME Tyrosine kinase receptor Cad96Ca OS=Drosophila melanogaster OX=7227 GN=Cad96Ca PE=2 SV=2 Length=773 Score = 139 bits (351), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 99/296 (33%), Positives = 151/296 (51%), Gaps = 37/296 (13%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE---MVAVKALKADCGPQHRSGWKQEI 948 F + LK LGEG FG+V + + TN E VAVK LK R E+ Sbjct 465 FPRYRLKFFNILGEGAFGQV--WRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSEL 522 Query 949 DILRTLY-HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRH---SIGLAQ 999 +++++L H +++ GCC D+ +++EYV G L+ YL RH + G + Sbjct 523 EVMKSLEPHINVVHLLGCCTDK--DPTFVILEYVNRGKLQTYLRSSRAERHYGNTHGKSN 580 Query 1000 LLL------FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 +L F Q+ +GM YL ++ IHRDLAARN+L+ +D K+ DFG A+ V Sbjct 581 VLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKI 640 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 Y R + +G P+ W A E L + F SD+WSFG+ ++E++T S+ P G Sbjct 641 YER-KSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVT-LGSTPYP--------G 690 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 I+ V+R + G RL +P+ C E+Y++M CW + RP F +I +L Sbjct 691 ISAAD--VMR---KVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQML 741 Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 57/223 (26%), Positives = 94/223 (42%), Gaps = 31/223 (14%) Query 669 HLAFVH--GVCVRGPENIMVTEYVEHGPLDVWLRRER-----GHVPMAWKMVVA------ 715 H+ VH G C ++ EYV G L +LR R G+ ++ + Sbjct 531 HINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRAERHYGNTHGKSNVLTSCDLTSF 590 Query 716 -QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE--ER 772 Q+A + YL ++ ++H ++ RNIL+ K++D G ++ + ER Sbjct 591 MYQVAKGMDYLTSRGIIHRDLAARNILIT-------DDHTCKVADFGFARDVITSKIYER 643 Query 773 VER----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 I W+A E L N S D W FG + EI G P S ++ + Sbjct 644 KSEGKLPIRWMATESLYD--NIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVR 701 Query 829 RQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 +RL PE +L + C +++P +RP F I++ L +L Sbjct 702 DGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDKL 744 >sp|Q06805|TIE1_BOVIN Tyrosine-protein kinase receptor Tie-1 OS=Bos taurus OX=9913 GN=TIE1 PE=2 SV=1 Length=1136 Score = 140 bits (354), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 98/281 (35%), Positives = 133/281 (47%), Gaps = 40/281 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961 +GEG+FG+V DG A+K LK + E+++L L +H +II Sbjct 843 IGEGNFGQVIRAMIK--KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIIN 900 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-----------GLA------QLLLFA 1004 G CE++G L + +EY P G+L D+L + + G A QLL FA Sbjct 901 LLGACENRG--YLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFA 958 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 GM YL + +IHRDLAARNVL+ + KI DFGL++ G E Y + G P Sbjct 959 SDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSR----GEEVYVKKTMGRLP 1014 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 V W A E L + SDVWSFGV L+E+++ L G MT L Sbjct 1015 VRWMAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCGMTCAEL 1060 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 E L + R+ +P C EVY LM+ CW RP F + Sbjct 1061 YEKLPQAYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQI 1101 Score = 55.5 bits (132), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 72/332 (22%), Positives = 129/332 (39%), Gaps = 54/332 (16%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 + L + R + P LN L + + +++ + GQ R + + L++ + Sbjct 811 SGTLTLTRRPKPQPEPLNYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKML 870 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 + + D RD EL V+ K+ HH ++ + G C Sbjct 871 KEYASEND----HRDFAGELEVLCKL---GHH------------------PNIINLLGAC 905 Query 678 VRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLASAL 722 + EY +G L +LR+ R + + A A+ + Sbjct 906 ENRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGM 965 Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP--WL 779 YL K +H ++ RN+L+ G + K++D G+ G + ++ + R+P W+ Sbjct 966 QYLSEKQFIHRDLAARNVLV-------GENLASKIADFGLSRGEEVYVKKTMGRLPVRWM 1018 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838 A E L + +T D W FG L EI G P + +E + +R+ +P +C Sbjct 1019 AIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQAYRMEQPRNC 1076 Query 839 -PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 ++ L QC P +RP F I L R+ Sbjct 1077 DDEVYELMRQCWRDRPYERPPFAQIALQLGRM 1108 >sp|Q60751|IGF1R_MOUSE Insulin-like growth factor 1 receptor OS=Mus musculus OX=10090 GN=Igf1r PE=1 SV=3 Length=1373 Score = 141 bits (355), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 95/291 (33%), Positives = 150/291 (52%), Gaps = 38/291 (13%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGE-----MVAVKALKADCGPQHRSGWKQEIDILRTLY 955 R+LG+G FG V Y+ G + VA+K + + R + E +++ Sbjct 1004 RELGQGSFGMV----YEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFN 1059 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSI-----GLAQLLLF 1003 H+++ G QG+ +L ++ME + G L+ YL ++++ L++++ Sbjct 1060 CHHVVRLLGVVS-QGQPTL-VIMELMTRGDLKSYLRSLRPEVEQNNLVLIPPSLSKMIQM 1117 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 A +I +GMAYL+A ++HRDLAARN ++ D VKIGDFG+ + + E +YYR G Sbjct 1118 AGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYE-TDYYRKGGKGLL 1176 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 PV W +PE LK+ F SDVWSFGV L+E+ T + G++ Q VLR Sbjct 1177 PVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQ---------GLSNEQ--VLR 1225 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + G L +PD CP ++ LM+ CW+ RP+F +I +K E Sbjct 1226 ---FVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEME 1273 Score = 84.3 bits (207), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 80/299 (27%), Positives = 126/299 (42%), Gaps = 47/299 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +++IT LGQG+ VYEG + G + DE E RV +K Sbjct 995 VAREKITMNRELGQGSFGMVYEGVAK---------GVVKDE----------PETRVAIKT 1035 Query 644 LD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 ++ + + F AS+M + + H+ + GV +G +++ E + G L +LR Sbjct 1036 VNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSL 1095 Query 703 RGHV---------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752 R V P KM+ +A ++A ++YL VH ++ RN ++A Sbjct 1096 RPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAE-------D 1148 Query 753 PFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 +K+ D G+ + + + + W++PE L G +T D W FG L E Sbjct 1149 FTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTHSDVWSFGVVLWE 1206 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTIL 863 I E P Q S + F L +P +CP L L C Y P RPSF I+ Sbjct 1207 IATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEII 1265 >sp|Q8BKG3|PTK7_MOUSE Inactive tyrosine-protein kinase 7 OS=Mus musculus OX=10090 GN=Ptk7 PE=1 SV=1 Length=1062 Score = 140 bits (354), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 91/301 (30%), Positives = 144/301 (48%), Gaps = 29/301 (10%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE-MVAVKALKADCGP 938 N A D F + L+ I LG+ FG+V L +G E +V VK+L++ Sbjct 771 TNKRHSAGDRMHFPRASLQPITTLGKSEFGEVFLAKAQGVEEGATETLVLVKSLQSR-DE 829 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------- 990 Q + +++E+++ L H ++++ G C + + +V+EYV LG L+ +L Sbjct 830 QQQLDFRREVEMFGKLNHANVVRLLGLCRE--AEPHYMVLEYVDLGDLKQFLRISKNKDE 887 Query 991 --PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + Q + Q+ GM +L ++H+DLAARN L+ R VK+ GL+K V Sbjct 888 KLKSQPLSTKQKVALCSQVALGMEHLSNNRFVHKDLAARNCLISAQRQVKVSALGLSKDV 947 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 EYY R+ P+ W +PE + E F SDVW+FGV ++E+ TH + Sbjct 948 -YNSEYYHFRQ-AWVPLRWMSPEAVLEGDFSTKSDVWAFGVLMWEVFTHGEMPHG----- 1000 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 GQ L +L RLP+P+ CP ++Y LM+ CW RP+F + Sbjct 1001 --------GQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWAPNPKDRPSFSEIAST 1052 Query 1169 L 1169 L Sbjct 1053 L 1053 Score = 77.0 bits (188), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 69/247 (28%), Positives = 108/247 (44%), Gaps = 25/247 (10%) Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 E V++K L L F + +++H ++ + G+C + MV EYV+ G L Sbjct 816 ETLVLVKSLQSRDEQQQLDFRREVEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDL 875 Query 696 DVWLRRERGH------VPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILLARLGL 747 +LR + P++ K VA Q+A + +L N VH ++ RN L++ Sbjct 876 KQFLRISKNKDEKLKSQPLSTKQKVALCSQVALGMEHLSNNRFVHKDLAARNCLIS---- 931 Query 748 AEGTSPFIKLSDPGVGLGALSREE---RVERIP--WLAPECLPGGANSLSTAMDKWGFGA 802 +K+S G+ + E R +P W++PE + G ST D W FG Sbjct 932 ---AQRQVKVSALGLSKDVYNSEYYHFRQAWVPLRWMSPEAVLEG--DFSTKSDVWAFGV 986 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQR-QHRLPEPS-CP-QLATLTSQCLTYEPTQRPSF 859 + E+ GE P ++ E Q + RLP+P CP +L L +C P RPSF Sbjct 987 LMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWAPNPKDRPSF 1046 Query 860 RTILRDL 866 I L Sbjct 1047 SEIASTL 1053 >sp|P14617|INSRR_CAVPO Insulin receptor-related protein OS=Cavia porcellus OX=10141 GN=INSRR PE=3 SV=1 Length=1300 Score = 140 bits (354), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 95/291 (33%), Positives = 148/291 (51%), Gaps = 41/291 (14%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDG--TGEM---VAVKALKADCGPQHRSGWKQEI 948 + + IR+LG+G FG V Y+ G GE VA+K + P+ R + +E Sbjct 976 REQISIIRELGQGSFGMV----YEGVAKGLEAGEESTPVALKTVNELASPRERIEFLKEA 1031 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------------PRHSI 995 +++ H+++ G QG+ +L ++ME + G L+ +L PR ++ Sbjct 1032 SVMKAFQCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSHLRSLRPEAENNPGIPRPAL 1089 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 G ++ A +I +GMAYL A ++HRDLAARN ++ D VKIGDFG+ + V E +YY Sbjct 1090 G--DMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYE-TDYY 1146 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 R G PV W APE LK+ F SDVWSFGV L+E++T + G++ Sbjct 1147 RKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQ---------GLS 1197 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 Q+ + + G L + CP ++ LM +CW+ RPTF ++ Sbjct 1198 NEQV-----LKFVMDGGVLEELEDCPHQLQELMSSCWQQNPRLRPTFTQIL 1243 Score = 75.1 bits (183), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 76/302 (25%), Positives = 125/302 (41%), Gaps = 44/302 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +++I+ + LGQG+ VYEG + +G+ + P+ L+ V ++ Sbjct 974 VPREQISIIRELGQGSFGMVYEGVAKGLEAGE-------ESTPVA--------LKTVNEL 1018 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 P + F + AS+M H+ + GV +G +++ E + G L LR R Sbjct 1019 ASPRER---IEFLKEASVMKAFQCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLR 1075 Query 704 GHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 P M+ +A ++A ++YL VH ++ RN ++++ Sbjct 1076 PEAENNPGIPRPALGDMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQ-------DFT 1128 Query 755 IKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 +K+ D G+ + + + + W+APE L G +T D W FG L EI Sbjct 1129 VKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGI--FTTHSDVWSFGVVLWEIV 1186 Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSFRTILRDL 866 E P Q S + F L E CP QL L S C P RP+F IL + Sbjct 1187 TLAEQPYQGLSNEQVLKFVMDGGVLEELEDCPHQLQELMSSCWQQNPRLRPTFTQILNSI 1246 Query 867 TR 868 + Sbjct 1247 QK 1248 >sp|Q64434|PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus musculus OX=10090 GN=Ptk6 PE=1 SV=1 Length=451 Score = 134 bits (338), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 93/275 (34%), Positives = 144/275 (52%), Gaps = 28/275 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 + LG G+FG+V ++ G VAVK + D H+ ++ EI ++ L H+HI+ Sbjct 195 KKLGAGYFGEV----FEALWKGQVH-VAVKVISRD-NLLHQHTFQAEIQAMKKLRHKHIL 248 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + ++ E +P G+L L ++ + +L+ FA Q+ EGM YL +Q Sbjct 249 SLYAVA--TAGDPVYIITELMPKGNLLQLLRDSDEKALPILELVDFASQVAEGMCYLESQ 306 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +YIHRDLAARNVL+ + L K+GDFGLA+ V E + + + P W APE L Sbjct 307 NYIHRDLAARNVLVTENNLCKVGDFGLARLVKED---IYLSHEHNVPYKWTAPEALSRGH 363 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + SDVWSFGV L+E+ + Q P G++ + T LR ++ G R+P P Sbjct 364 YSIKSDVWSFGVLLHEIFS---RGQMPYP------GMSNHE-TFLR----VDAGYRMPCP 409 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +CP ++ LM +CW + RP F++L L + Sbjct 410 LECPPNIHKLMLSCWSRDPKQRPCFKDLCEKLTGI 444 Score = 79.7 bits (195), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 68/239 (28%), Positives = 107/239 (45%), Gaps = 11/239 (5%) Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 +GQ + V +KV+ + F M ++ H H+ ++ V G ++TE + Sbjct 211 KGQ-VHVAVKVISRDNLLHQHTFQAEIQAMKKLRHKHILSLYAVATAGDPVYIITELMPK 269 Query 693 GPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE-G 750 G L LR + +P+ + A Q+A + YLE++N +H ++ RN+L+ L + G Sbjct 270 GNLLQLLRDSDEKALPILELVDFASQVAEGMCYLESQNYIHRDLAARNVLVTENNLCKVG 329 Query 751 TSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +L + LS E V W APE L G S+ + D W FG L EI Sbjct 330 DFGLARLVKEDI---YLSHEHNVP-YKWTAPEALSRGHYSIKS--DVWSFGVLLHEIFSR 383 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEPTQRPSFRTILRDLT 867 G+ P S E +R+P P C P + L C + +P QRP F+ + LT Sbjct 384 GQMPYPGMSNHETFLRVDAGYRMPCPLECPPNIHKLMLSCWSRDPKQRPCFKDLCEKLT 442 >sp|P18106|FER_DROME Tyrosine-protein kinase Fer OS=Drosophila melanogaster OX=7227 GN=FER PE=1 SV=3 Length=1325 Score = 140 bits (352), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 94/271 (35%), Positives = 137/271 (51%), Gaps = 29/271 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G+FG V Y T VAVK + + + + QE IL+ H +I+K Sbjct 1069 IGRGNFGDV----YKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKL 1124 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHYI 1020 G C + + + +VME V GSL YL ++S GL Q + + GM YL +++ I Sbjct 1125 IGICVQK--QPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCI 1182 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVFWYAPECLKEYKF 1078 HRDLAARN L+D + VKI DFG+++ E EY + DG PV W APE L K+ Sbjct 1183 HRDLAARNCLVDLEHSVKISDFGMSR---EEEEY--IVSDGMKQIPVKWTAPEALNFGKY 1237 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 DVWS+G+ ++E+ + D+ S MT R E ++ G R+P P Sbjct 1238 TSLCDVWSYGILMWEIFSKGDTPYSG--------------MTNSRARERIDTGYRMPTPK 1283 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P E+Y LM CW +A RP F+ + ++ Sbjct 1284 STPEEMYRLMLQCWAADAESRPHFDEIYNVV 1314 Score = 80.1 bits (196), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 64/241 (27%), Positives = 108/241 (45%), Gaps = 34/241 (14%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F + ++ Q H ++ + G+CV+ ++V E V G L +LR+ + +M + Sbjct 1106 FLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGM 1165 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-- 772 + A+ + YLE+KN +H ++ RN L+ +K+SD G +SREE Sbjct 1166 CRDAAAGMRYLESKNCIHRDLAARNCLV-------DLEHSVKISDFG-----MSREEEEY 1213 Query 773 -----VERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 +++IP W APE L G ++ D W +G + EI G+ P + S Sbjct 1214 IVSDGMKQIPVKWTAPEALNFG--KYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARE 1271 Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 +R+P P S P ++ L QC + RP F I +N+ D L + D Sbjct 1272 RIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEI---------YNVVDALILRLD 1322 Query 884 S 884 + Sbjct 1323 N 1323 >sp|Q61772|EPHA7_MOUSE Ephrin type-A receptor 7 OS=Mus musculus OX=10090 GN=Epha7 PE=1 SV=2 Length=998 Score = 139 bits (351), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 86/276 (31%), Positives = 143/276 (52%), Gaps = 21/276 (8%) Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 +K R +G G FG+V S P VA+K LK + R + E I+ Sbjct 633 IKIERVIGAGEFGEVCSGRLKLPGKRDVA--VAIKTLKVGYTEKQRRDFLCEASIMGQFD 690 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAY 1013 H +++ +G K + +V+E++ G+L +L +H + QL+ + I GM Y Sbjct 691 HPNVVHLEGVVTRG--KPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRY 748 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 L Y+HRDLAARN+L++++ + K+ DFGL++ + + E G PV W APE + Sbjct 749 LADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAI 808 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF ASDVWS+G+ ++E++++ + P M+ + + +E G R Sbjct 809 QYRKFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMSNQDVIKAIEEGYR 854 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 LP P CP ++ LM +CW+ + + RP FE ++ IL Sbjct 855 LPAPMDCPAGLHQLMLDCWQKDRAERPKFEQIVGIL 890 Score = 87.4 bits (215), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 74/271 (27%), Positives = 126/271 (46%), Gaps = 24/271 (9%) Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSH 667 RV G+G E G++ +PG+ +++ V +K L + + F AS+M Q H Sbjct 637 RVIGAG--EFGEVCSGRLKLPGK---RDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDH 691 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 ++ + GV RG ++V E++E+G LD +LR+ G + + + + +A+ + YL + Sbjct 692 PNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLAD 751 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIP--WLA 780 VH ++ RNIL+ ++ K+SD G+ E V +IP W A Sbjct 752 MGYVHRDLAARNILV-------NSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTA 804 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP 839 PE + ++A D W +G + E+ GE P S + + +RLP P CP Sbjct 805 PEAIQ--YRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCP 862 Query 840 Q-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 L L C + +RP F I+ L ++ Sbjct 863 AGLHQLMLDCWQKDRAERPKFEQIVGILDKM 893 >sp|P00541|FPS_AVISP Tyrosine-protein kinase transforming protein Fps OS=Avian sarcoma virus (strain PRCII) OX=11880 GN=V-FPS PE=3 SV=1 Length=533 Score = 135 bits (341), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 88/274 (32%), Positives = 139/274 (51%), Gaps = 27/274 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G+FG+V + D T VAVK+ + P+ ++ + QE IL+ H +I++ Sbjct 278 IGRGNFGEV--FSGRLRADNTP--VAVKSCRETLPPELKAKFLQEARILKQYNHPNIVRL 333 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C + + + +VME V G +L + + +L+ + GM YL ++H I Sbjct 334 IGVCTQK--QPIYIVMELVQGGDFLSFLRSKGPHLKMKELIKMMENAAAGMEYLESKHCI 391 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARN L+ +KI DFG+++ +G Y PV W APE L ++ Sbjct 392 HRDLAARNCLVTEKNTLKISDFGMSRQEEDG-VYASTGGMKQIPVKWTAPEALNYGRYSS 450 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWSFG+ L+E + L + ++ + E +E+G RL P++C Sbjct 451 ESDVWSFGILLWEAFS--------------LGAVPYANLSNQQTREAIEQGVRLEPPEQC 496 Query 1141 PCEVYHLMKNCWETEASFRPTF----ENLIPILK 1170 P +VY LM+ CWE + RP+F ++LI I K Sbjct 497 PEDVYRLMQRCWEYDPRRRPSFGAVHQDLIAIRK 530 Score = 86.3 bits (212), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 73/284 (26%), Positives = 127/284 (45%), Gaps = 40/284 (14%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 +G+G V+ GRLR D P+ ++ + L P ++ Sbjct 278 IGRGNFGEVFSGRLRA------------DNTPVA--------VKSCRETLPP---ELKAK 314 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F + A ++ Q +H ++ + GVC + +V E V+ G +LR + H+ M + + Sbjct 315 FLQEARILKQYNHPNIVRLIGVCTQKQPIYIVMELVQGGDFLSFLRSKGPHLKMKELIKM 374 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSRE 770 + A+ + YLE+K+ +H ++ RN L+ +K+SD G+ G + Sbjct 375 MENAAAGMEYLESKHCIHRDLAARNCLVTEKNT-------LKISDFGMSRQEEDGVYAST 427 Query 771 ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 +++IP W APE L G S+ D W FG L E G P + S + + Sbjct 428 GGMKQIPVKWTAPEALNYG--RYSSESDVWSFGILLWEAFSLGAVPYANLSNQQTREAIE 485 Query 829 RQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + RL P CP+ + L +C Y+P +RPSF + +DL ++ Sbjct 486 QGVRLEPPEQCPEDVYRLMQRCWEYDPRRRPSFGAVHQDLIAIR 529 >sp|Q9TTY2|FER_CANLF Tyrosine-protein kinase Fer OS=Canis lupus familiaris OX=9615 GN=FER PE=2 SV=1 Length=823 Score = 138 bits (348), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 91/276 (33%), Positives = 139/276 (50%), Gaps = 27/276 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G+FG+V D T VAVK K D + + + QE IL+ H +I+K Sbjct 569 LGKGNFGEV---YKGILKDKTA--VAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKL 623 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C + + + ++ME VP G +L + I L QL+ F+ GM+YL +++ I Sbjct 624 IGVCTQR--QPIYIIMELVPGGDFLSFLRKKKDEIKLKQLVKFSLDAASGMSYLESKNCI 681 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARN L+ + ++KI DFG+++ G Y P+ W APE L ++ Sbjct 682 HRDLAARNCLVGENNVLKISDFGMSRQEDGG--VYSSSGLKQIPIKWTAPEALNYGRYSS 739 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA-QGQMTVLRLTELLERGERLPRPDK 1139 SDVWSFG+ L+E + +G+ MT + TE +ERG R+ P Sbjct 740 ESDVWSFGILLWETFS---------------LGVCPYPGMTNQQATEQVERGYRISAPQH 784 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 CP +++ +M CW+ + RP F L L + +K Sbjct 785 CPEDIFKIMMKCWDYKPENRPKFSELQKELTVIKKK 820 Score = 89.7 bits (221), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 60/229 (26%), Positives = 110/229 (48%), Gaps = 16/229 (7%) Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 ++ + F + A ++ Q H ++ + GVC + ++ E V G +LR+++ + + Sbjct 599 QELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPIYIIMELVPGGDFLSFLRKKKDEIKL 658 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---G 765 + + AS +SYLE+KN +H ++ RN L+ G + +K+SD G+ G Sbjct 659 KQLVKFSLDAASGMSYLESKNCIHRDLAARNCLV-------GENNVLKISDFGMSRQEDG 711 Query 766 ALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + +++IP W APE L G S+ D W FG L E G P + + Sbjct 712 GVYSSSGLKQIPIKWTAPEALNYG--RYSSESDVWSFGILLWETFSLGVCPYPGMTNQQA 769 Query 824 EHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 +R +R+ P CP+ + + +C Y+P RP F + ++LT ++ Sbjct 770 TEQVERGYRISAPQHCPEDIFKIMMKCWDYKPENRPKFSELQKELTVIK 818 >sp|Q60805|MERTK_MOUSE Tyrosine-protein kinase Mer OS=Mus musculus OX=10090 GN=Mertk PE=1 SV=1 Length=994 Score = 139 bits (349), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 94/288 (33%), Positives = 139/288 (48%), Gaps = 29/288 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEI 948 V + L + LGEG FG V + DGT + VAVK +K D Q + E Sbjct 575 VVIDRNLLVLGKVLGEGEFGSV-MEGNLKQEDGTSQKVAVKTMKLDNFSQREIEEFLSEA 633 Query 949 DILRTLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGSLRDYL--------PRHSIGL 997 ++ H ++I+ G C QG +++ ++ G L +L P++ I L Sbjct 634 ACMKDFNHPNVIRLLGVCIELSSQGIPKPMVILPFMKYGDLHTFLLYSRLNTGPKY-IHL 692 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 LL F I +GM YL ++++HRDLAARN +L +D V + DFGL+K + G +YYR Sbjct 693 QTLLKFMMDIAQGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQ 751 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 PV W A E L + + SDVW+FGVT++E+ T G+ Sbjct 752 GRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEITTR---------GMTPYPGVQNH 802 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 +M + L G RL +P+ C E+Y +M +CW + RPTF L Sbjct 803 EM-----YDYLLHGHRLKQPEDCLDELYDIMYSCWSADPLDRPTFSVL 845 Score = 71.6 bits (174), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 75/317 (24%), Positives = 134/317 (42%), Gaps = 35/317 (11%) Query 606 GRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664 G++ EG G EG + ED Q++ V LD F A+ M Sbjct 585 GKVLGEGEFGSVMEGNLKQED------GTSQKVAVKTMKLDNFSQREIEEFLSEAACMKD 638 Query 665 VSHTHLAFVHGVCVR-----GPENIMVTEYVEHGPLDVWLRRER-----GHVPMAWKMVV 714 +H ++ + GVC+ P+ +++ ++++G L +L R ++ + + Sbjct 639 FNHPNVIRLLGVCIELSSQGIPKPMVILPFMKYGDLHTFLLYSRLNTGPKYIHLQTLLKF 698 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 +A + YL N+N +H ++ RN +L R + + F LS + G R+ R+ Sbjct 699 MMDIAQGMEYLSNRNFLHRDLAARNCML-RDDMTVCVADF-GLSK-KIYSGDYYRQGRIA 755 Query 775 RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832 ++P W+A E L ++ D W FG T+ EI G P E + HR Sbjct 756 KMPVKWIAIESL--ADRVYTSKSDVWAFGVTMWEITTRGMTPYPGVQNHEMYDYLLHGHR 813 Query 833 L--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 L PE +L + C + +P RP+F + RLQ L++ L PD+ + Sbjct 814 LKQPEDCLDELYDIMYSCWSADPLDRPTFSVL-----RLQLEKLSESL---PDAQDKESI 865 Query 891 VF-HKRYLKKIRDLGEG 906 ++ + + L+ + G Sbjct 866 IYINTQLLESCEGIANG 882 >sp|Q91845|EPA4A_XENLA Ephrin type-A receptor 4-A OS=Xenopus laevis OX=8355 GN=epha4-a PE=2 SV=1 Length=986 Score = 139 bits (349), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 87/277 (31%), Positives = 143/277 (52%), Gaps = 23/277 (8%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTL 954 +K + +G G FG+V C G E+ VA+K LKA + R + E I+ Sbjct 620 IKIEKVIGVGEFGEV---CSGRLKVPGKREIYVAIKTLKAGYTDKQRRDFLSEASIMGQF 676 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMA 1012 H +II +G K + ++ EY+ GSL +L ++ + QL+ + I GM Sbjct 677 DHPNIIHLEGVVTKC--KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGILRGIGSGMK 734 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 YL Y+HRDLAARN+L++++ + K+ DFG+++ + + E G P+ W APE Sbjct 735 YLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEA 794 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + KF ASDVWS+G+ ++E++++ + P M+ + + +E G Sbjct 795 IAYRKFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMSNQDVIKAIEEGY 840 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 RLP P CP ++ LM +CW+ E S RP F ++ +L Sbjct 841 RLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVSML 877 Score = 94.0 bits (232), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 74/259 (29%), Positives = 121/259 (47%), Gaps = 24/259 (9%) Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 VPG+ +E+ V +K L + D F AS+M Q H ++ + GV + +++ Sbjct 641 VPGK---REIYVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMII 697 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TEY+E+G LD +LR+ G + + + + + S + YL + + VH ++ RNIL+ Sbjct 698 TEYMENGSLDAFLRKNDGRFTVIQLVGILRGIGSGMKYLSDMSYVHRDLAARNILV---- 753 Query 747 LAEGTSPFIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWG 799 ++ K+SD G+ E R +IP W APE + ++A D W Sbjct 754 ---NSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAI--AYRKFTSASDVWS 808 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRP 857 +G + E+ GE P S + + +RLP P CP L L C E + RP Sbjct 809 YGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRP 868 Query 858 SFRTILRDLTRL--QPHNL 874 F I+ L +L P++L Sbjct 869 KFGQIVSMLDKLIRNPNSL 887 >sp|O73791|TIE2_DANRE Angiopoietin-1 receptor OS=Danio rerio OX=7955 GN=tek PE=1 SV=1 Length=1116 Score = 139 bits (349), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 99/291 (34%), Positives = 141/291 (48%), Gaps = 40/291 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL-RTLYHEHIIK 961 LGEG+FG+V DG AVK +K + E+++L R H++II Sbjct 822 LGEGNFGQV--LKARIRKDGLRMDAAVKRMKDYASQDDHRDFAGELEVLCRLGPHKNIIH 879 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFA 1004 G CE +G L L +E+ P G+L D+L + ++ QLL F+ Sbjct 880 LLGACEHRGY--LYLAIEFAPHGNLLDFLRKSRVLETDPAFAIAHRTASTLSSQQLLAFS 937 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 + GM+YL + +IHRDLAARNVL+ + + KI DFGL++ G E Y + G P Sbjct 938 ADVARGMSYLSQKQFIHRDLAARNVLVGENFVAKIADFGLSR----GQEVYVKKTMGRLP 993 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 V W A E L + SDVWS+GV L+E+++ L G MT L Sbjct 994 VRWMAIESLNYSVYTTNSDVWSYGVLLWEVVS--------------LGGTPYCGMTCAEL 1039 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 E L G RL +P C EVY LM+ CW + RP+F ++ L + E+ Sbjct 1040 YEKLPLGFRLEKPLNCDDEVYELMQQCWREKPFERPSFSQILLSLGRMLEE 1090 Score = 62.4 bits (150), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 78/312 (25%), Positives = 125/312 (40%), Gaps = 51/312 (16%) Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG-SGDPEEGKMDDEDPLVPGRDRGQEL 637 L F + +I LG+G V + R+R +G D +M D RD EL Sbjct 806 LVFPALQWSDIQFQDVLGEGNFGQVLKARIRKDGLRMDAAVKRMKDYASQDDHRDFAGEL 865 Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V+ + L P H ++ + G C + E+ HG L Sbjct 866 EVLCR-LGP--------------------HKNIIHLLGACEHRGYLYLAIEFAPHGNLLD 904 Query 698 WLRRER--------GHVPMAWKMVVAQQL-------ASALSYLENKNLVHGNVCGRNILL 742 +LR+ R + +QQL A +SYL K +H ++ RN+L+ Sbjct 905 FLRKSRVLETDPAFAIAHRTASTLSSQQLLAFSADVARGMSYLSQKQFIHRDLAARNVLV 964 Query 743 ARLGLAEGTSPFIKLSDPGVGLGA-LSREERVERIP--WLAPECLPGGANSLSTAMDKWG 799 G + K++D G+ G + ++ + R+P W+A E L + +T D W Sbjct 965 -------GENFVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESL--NYSVYTTNSDVWS 1015 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEPTQRP 857 +G L E+ G P + +E RL +P +C ++ L QC +P +RP Sbjct 1016 YGVLLWEVVSLGGTPYCGMTCAELYEKLPLGFRLEKPLNCDDEVYELMQQCWREKPFERP 1075 Query 858 SFRTILRDLTRL 869 SF IL L R+ Sbjct 1076 SFSQILLSLGRM 1087 >sp|Q07496|EPHA4_CHICK Ephrin type-A receptor 4 OS=Gallus gallus OX=9031 GN=EPHA4 PE=1 SV=2 Length=986 Score = 139 bits (349), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 90/294 (31%), Positives = 148/294 (50%), Gaps = 31/294 (11%) Query 888 DPTVFHKRYLKKI--------RDLGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCG 937 DP + + K+I + +G G FG+V C G E+ VA+K LKA Sbjct 604 DPNQAVREFAKEIDASCIKIEKVIGVGEFGEV---CSGRLKVPGKREICVAIKTLKAGYT 660 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995 + R + E I+ H +II +G K + ++ EY+ GSL +L ++ Sbjct 661 DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKC--KPVMIITEYMENGSLDAFLRKNDGRF 718 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFG+++ + + E Sbjct 719 TVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAA 778 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 G P+ W APE + KF ASDVWS+G+ ++E++++ + P Sbjct 779 YTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY---GERP----------- 824 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 M+ + + +E G RLP P CP ++ LM +CW+ E S RP F ++ +L Sbjct 825 YWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNML 878 Score = 94.0 bits (232), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 94/357 (26%), Positives = 154/357 (43%), Gaps = 53/357 (15%) Query 586 QKEITQLSHLGQGTRTNV----YE---------------GRLRVEGS-GDPEEGKMDDED 625 ++E + HL QG RT V YE +++E G E G++ Sbjct 580 KQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGR 639 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 VPG+ +E+ V +K L + D F AS+M Q H ++ + GV + + Sbjct 640 LKVPGK---REICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVM 696 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 ++TEY+E+G LD +LR+ G + + + + + S + YL + + VH ++ RNIL+ Sbjct 697 IITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILV-- 754 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDK 797 ++ K+SD G+ E R +IP W APE + ++A D Sbjct 755 -----NSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAI--AYRKFTSASDV 807 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQ 855 W +G + E+ GE P S + + +RLP P CP L L C E + Sbjct 808 WSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSD 867 Query 856 RPSFRTILRDLTRL--QPHNLA---------DVLTVNPDSPASDPTVFHKRYLKKIR 901 RP F I+ L +L P++L ++P SP V +L+ I+ Sbjct 868 RPKFGQIVNMLDKLIRNPNSLKRTGSESSRPSTALLDPSSPEFSAVVSVSDWLQAIK 924 >sp|Q60750|EPHA1_MOUSE Ephrin type-A receptor 1 OS=Mus musculus OX=10090 GN=Epha1 PE=1 SV=2 Length=977 Score = 138 bits (348), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 87/266 (33%), Positives = 134/266 (50%), Gaps = 22/266 (8%) Query 903 LGEGHFGKVSLYCYD-PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG FG+V P+ D + VA+K LK + + +E I+ H HI++ Sbjct 631 IGEGEFGEVYRGALRLPSQDC--KTVAIKTLKDTSPDGYWWNFLREATIMGQFNHPHILR 688 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019 +G + K + ++ E++ G+L +L LA QL+ I GM L +Y Sbjct 689 LEGVITKR--KPIMIITEFMENGALDAFLKEREDQLAPGQLVAMLLGIASGMNCLSGHNY 746 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDLAARN+L++ + K+ DFGL + + + Y + G P+ W APE + F Sbjct 747 VHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYET-QGGKIPIRWTAPEAIAHRIFT 805 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 ASDVWSFG+ ++E+L+ D G+M+ + + +E G RLP P Sbjct 806 TASDVWSFGIVMWEVLSFGDK--------------PYGEMSNQEVMKSIEDGYRLPPPVD 851 Query 1140 CPCEVYHLMKNCWETEASFRPTFENL 1165 CP +Y LMKNCW + + RP F L Sbjct 852 CPAPLYELMKNCWAYDRARRPHFLQL 877 Score = 90.1 bits (222), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 73/253 (29%), Positives = 116/253 (46%), Gaps = 16/253 (6%) Query 639 VVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V +K L D S F A++M Q +H H+ + GV + +++TE++E+G LD Sbjct 654 VAIKTLKDTSPDGYWWNFLREATIMGQFNHPHILRLEGVITKRKPIMIITEFMENGALDA 713 Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF--I 755 +L+ + + + +AS ++ L N VH ++ RNIL+ + L S F Sbjct 714 FLKEREDQLAPGQLVAMLLGIASGMNCLSGHNYVHRDLAARNILVNQ-NLCCKVSDFGLT 772 Query 756 KLSDPGVGLGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 +L D G + E + +IP W APE + +TA D W FG + E+ G+ Sbjct 773 RLLDDFDG----TYETQGGKIPIRWTAPEAI--AHRIFTTASDVWSFGIVMWEVLSFGDK 826 Query 814 PLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL-- 869 P S E + +RLP P CP L L C Y+ +RP F + L +L Sbjct 827 PYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFLQLQAHLEQLLT 886 Query 870 QPHNLADVLTVNP 882 PH+L + +P Sbjct 887 DPHSLRTIANFDP 899 >sp|Q62838|MUSK_RAT Muscle, skeletal receptor tyrosine protein kinase OS=Rattus norvegicus OX=10116 GN=Musk PE=1 SV=1 Length=868 Score = 138 bits (347), Expect = 8e-32, Method: Compositional matrix adjust. Identities = 89/318 (28%), Positives = 155/318 (49%), Gaps = 53/318 (17%) Query 892 FHKRYLKKIRDLGEGHFGKV------SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 + + ++ +RD+GEG FG+V L Y+P MVAVK LK + ++ ++ Sbjct 569 YPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFT-----MVAVKMLKEEASADMQADFQ 623 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------- 994 +E ++ + +I+K G C K + L+ EY+ G L ++L S Sbjct 624 REAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSD 681 Query 995 --------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040 + A+ L A+Q+ GMAYL + ++HRDLA RN L+ + +VKI Sbjct 682 LSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIA 741 Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100 DFGL++ + +YY+ + P+ W PE + ++ SDVW++GV L+E+ ++ Sbjct 742 DFGLSRNIYSA-DYYKADGNDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSY--- 797 Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 G+A ++ + G L P+ CP E+Y+LM+ CW + RP Sbjct 798 ------GLQPYYGMAHEEVIY-----YVRDGNILACPENCPLELYNLMRLCWSKLPADRP 846 Query 1161 TFENLIPILKTVHEKYQG 1178 +F ++ IL+ + E+ +G Sbjct 847 SFCSIHRILQRMCERAEG 864 Score = 77.0 bits (188), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 67/263 (25%), Positives = 120/263 (46%), Gaps = 41/263 (16%) Query 639 VVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V +K+L + + D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+ Sbjct 605 VAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNE 664 Query 698 WLRRERGH-----------------------VPMAWKMVVAQQLASALSYLENKNLVHGN 734 +LR H + A ++ +A+Q+A+ ++YL + VH + Sbjct 665 FLRSMSPHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRD 724 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGA 788 + RN L+ G + +K++D G+ S + + + IP W+ PE + Sbjct 725 LATRNCLV-------GENMVVKIADFGLSRNIYSADYYKADGNDAIPIRWMPPESI--FY 775 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTS 846 N +T D W +G L EI G P + E ++ + + L P +CP +L L Sbjct 776 NRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILACPENCPLELYNLMR 835 Query 847 QCLTYEPTQRPSFRTILRDLTRL 869 C + P RPSF +I R L R+ Sbjct 836 LCWSKLPADRPSFCSIHRILQRM 858 >sp|Q03137|EPHA4_MOUSE Ephrin type-A receptor 4 OS=Mus musculus OX=10090 GN=Epha4 PE=1 SV=2 Length=986 Score = 138 bits (347), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 78/245 (32%), Positives = 129/245 (53%), Gaps = 18/245 (7%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VA+K LKA + R + E I+ H +II +G K + ++ EY+ GSL Sbjct 650 VAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKC--KPVMIITEYMENGSL 707 Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L ++ + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFG+ Sbjct 708 DAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGM 767 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 ++ + + E G P+ W APE + KF ASDVWS+G+ ++E++++ + P Sbjct 768 SRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY---GERP 824 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 M+ + + +E G RLP P CP ++ LM +CW+ E S RP F Sbjct 825 -----------YWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQ 873 Query 1165 LIPIL 1169 ++ +L Sbjct 874 IVNML 878 Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 80/295 (27%), Positives = 133/295 (45%), Gaps = 33/295 (11%) Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 VPG+ +E+ V +K L + D F AS+M Q H ++ + GV + +++ Sbjct 642 VPGK---REICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMII 698 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TEY+E+G LD +LR+ G + + + + + S + YL + + VH ++ RNIL+ Sbjct 699 TEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILV---- 754 Query 747 LAEGTSPFIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWG 799 ++ K+SD G+ E R +IP W APE + ++A D W Sbjct 755 ---NSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAI--AYRKFTSASDVWS 809 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRP 857 +G + E+ GE P S + + +RLP P CP L L C E + RP Sbjct 810 YGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRP 869 Query 858 SFRTILRDLTRL--QPHNLA---------DVLTVNPDSPASDPTVFHKRYLKKIR 901 F I+ L +L P++L + ++P SP V +L+ I+ Sbjct 870 KFGQIVNMLDKLIRNPNSLKRTGSESSRPNTALLDPSSPEFSAVVSVGDWLQAIK 924 >sp|Q03146|DDR1_MOUSE Epithelial discoidin domain-containing receptor 1 OS=Mus musculus OX=10090 GN=Ddr1 PE=2 SV=2 Length=911 Score = 137 bits (346), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 98/309 (32%), Positives = 139/309 (45%), Gaps = 47/309 (15%) Query 892 FHKRYLKKIRDLGEGHFGKVSL-YCYDPTN-----------DGTGEMVAVKALKADCGPQ 939 F + L+ LGEG FG+V L DP + G +VAVK L+ D Sbjct 603 FPRSRLRFKEKLGEGQFGEVHLCEVEDPQDLVSSDFPISVHKGHPLLVAVKILRPDATKN 662 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------ 993 R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L Sbjct 663 ARNDFLKEVKIMSRLKDPNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSARQLENKA 720 Query 994 --------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 +I LL QI GM YL +++HRDLA RN L+ + +KI Sbjct 721 TQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKI 780 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+L C Sbjct 781 ADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCR 839 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER---LPRPDKCPCEVYHLMKNCWETEA 1156 S + G + + E R L RP CP +Y LM CW E Sbjct 840 S---------QPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQTLYELMLRCWSREP 890 Query 1157 SFRPTFENL 1165 RP F L Sbjct 891 EQRPPFAQL 899 Score = 77.8 bits (190), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 76/270 (28%), Positives = 121/270 (45%), Gaps = 44/270 (16%) Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +G L V +K+L P A F + +MS++ ++ + GVCV+ M+T+Y+E Sbjct 644 KGHPLLVAVKILRPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYME 703 Query 692 HGPLDVWLR---------------RERGHVP-MAWKMV--VAQQLASALSYLENKNLVHG 733 +G L+ +L E P +++ M+ V Q+AS + YL N VH Sbjct 704 NGDLNQFLSARQLENKATQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHR 763 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGG 787 ++ RN L+ G + IK++D G+ + + V I W+A EC+ G Sbjct 764 DLATRNCLV-------GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG 816 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-----EHFYQRQHRLP----EPSC 838 +TA D W FG TL E+ + + E+ F++ Q R P+C Sbjct 817 --KFTTASDVWAFGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPAC 874 Query 839 PQ-LATLTSQCLTYEPTQRPSFRTILRDLT 867 PQ L L +C + EP QRP F + R L Sbjct 875 PQTLYELMLRCWSREPEQRPPFAQLHRFLA 904 >sp|P54764|EPHA4_HUMAN Ephrin type-A receptor 4 OS=Homo sapiens OX=9606 GN=EPHA4 PE=1 SV=1 Length=986 Score = 137 bits (346), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 78/245 (32%), Positives = 129/245 (53%), Gaps = 18/245 (7%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VA+K LKA + R + E I+ H +II +G K + ++ EY+ GSL Sbjct 650 VAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKC--KPVMIITEYMENGSL 707 Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L ++ + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFG+ Sbjct 708 DAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGM 767 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 ++ + + E G P+ W APE + KF ASDVWS+G+ ++E++++ + P Sbjct 768 SRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY---GERP 824 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 M+ + + +E G RLP P CP ++ LM +CW+ E S RP F Sbjct 825 -----------YWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQ 873 Query 1165 LIPIL 1169 ++ +L Sbjct 874 IVNML 878 Score = 94.4 bits (233), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 81/295 (27%), Positives = 133/295 (45%), Gaps = 33/295 (11%) Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 VPG+ +E+ V +K L + D F AS+M Q H ++ + GV + +++ Sbjct 642 VPGK---REICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMII 698 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TEY+E+G LD +LR+ G + + + + + S + YL + + VH ++ RNIL+ Sbjct 699 TEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILV---- 754 Query 747 LAEGTSPFIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWG 799 ++ K+SD G+ E R +IP W APE + ++A D W Sbjct 755 ---NSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAI--AYRKFTSASDVWS 809 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRP 857 +G + E+ GE P S + + +RLP P CP L L C E + RP Sbjct 810 YGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRP 869 Query 858 SFRTILRDLTRL--QPHNLADVLT---------VNPDSPASDPTVFHKRYLKKIR 901 F I+ L +L P++L T ++P SP V +L+ I+ Sbjct 870 KFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVSVGDWLQAIK 924 >sp|P29322|EPHA8_HUMAN Ephrin type-A receptor 8 OS=Homo sapiens OX=9606 GN=EPHA8 PE=1 SV=2 Length=1005 Score = 137 bits (346), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 82/248 (33%), Positives = 128/248 (52%), Gaps = 18/248 (7%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VA+KALKA + R + E I+ H +II+ +G +G ++ +V EY+ GSL Sbjct 664 VAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVT-RGRLAM-IVTEYMENGSL 721 Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L H + QL+ + + GM YL Y+HRDLAARNVL+D++ + K+ DFGL Sbjct 722 DTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGL 781 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 ++ + + + G P+ W APE + F ASDVWSFGV ++E+L + + Sbjct 782 SRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGER---- 837 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 MT + +E G RLP P CP ++ LM +CW + + RP F Sbjct 838 ----------PYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQ 887 Query 1165 LIPILKTV 1172 ++ +L + Sbjct 888 IVSVLDAL 895 Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 87/329 (26%), Positives = 137/329 (42%), Gaps = 52/329 (16%) Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 R R+ R + S++ ++ +G G V GRLRV G D Sbjct 621 RAGRSFTREIEASRIHIEKI----------IGSGDSGEVCYGRLRVPGQRD--------- 661 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPEN 683 VP V +K L + + F AS+M Q H ++ + GV RG Sbjct 662 ---VP---------VAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLA 709 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 ++VTEY+E+G LD +LR G + + + + + + + YL + VH ++ RN+L+ Sbjct 710 MIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLV- 768 Query 744 RLGLAEGTSPFIKLSDPGVGL-------GALSREERVERIPWLAPECLPGGANSLSTAMD 796 ++ K+SD G+ A + I W APE + + S+A D Sbjct 769 ------DSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAI--AFRTFSSASD 820 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPT 854 W FG + E+ GE P + + + + +RLP P CP L L C + Sbjct 821 VWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRA 880 Query 855 QRPSFRTILRDLTRL--QPHNLADVLTVN 881 QRP F I+ L L P +L TV+ Sbjct 881 QRPRFSQIVSVLDALIRSPESLRATATVS 909 >sp|P00529|ROS_AVISU Tyrosine-protein kinase transforming protein ros OS=UR2 avian sarcoma virus OX=354090 GN=V-ROS PE=3 SV=1 Length=402 Score = 132 bits (331), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 97/278 (35%), Positives = 135/278 (49%), Gaps = 37/278 (13%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG G FG+V D DG+GE VAVK LK Q +S + +E ++ H HI+ Sbjct 104 LGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMSKFDHPHIL 163 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQLLLFAQQICEG 1010 K G C + L++E + G L YL P ++ + IC+G Sbjct 164 KLLGVCLLNEPQ--YLILELMEGGDLLSYLRGARKQKFQSPLLTLTDLLDICL--DICKG 219 Query 1011 MAYLHAQHYIHRDLAARNVLLDN------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 YL +IHRDLAARN L+ R+VKIGDFGLA+ + + ++YYR R +G P Sbjct 220 CVYLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYK-NDYYRKRGEGLLP 278 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 V W APE L + F SDVW+FGV ++E LT Q P ++ + + Sbjct 279 VRWMAPESLIDGVFTNHSDVWAFGVLVWETLT---LGQQPYPG-----------LSNIEV 324 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 + G RL P+ CP ++ LM CW + RPTF Sbjct 325 LHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTF 362 Score = 74.7 bits (182), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 74/294 (25%), Positives = 116/294 (39%), Gaps = 42/294 (14%) Query 595 LGQGTRTNVYEGR---LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651 LG G VYEG + +GSG E RV +K L D Sbjct 104 LGSGAFGEVYEGTALDILADGSG---------------------ESRVAVKTLKRGATDQ 142 Query 652 ALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH----- 705 + F + A LMS+ H H+ + GVC+ ++ E +E G L +LR R Sbjct 143 EKSEFLKEAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRGARKQKFQSP 202 Query 706 -VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + + + + YLE +H ++ RN L++ S +K+ D G+ Sbjct 203 LLTLTDLLDICLDICKGCVYLEKMRFIHRDLAARNCLVSEKQYGS-CSRVVKIGDFGLAR 261 Query 765 GALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + +R + W+APE L G + D W FG + E G+ P Sbjct 262 DIYKNDYYRKRGEGLLPVRWMAPESLIDGV--FTNHSDVWAFGVLVWETLTLGQQPYPGL 319 Query 819 SPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 S E H + RL P +CP + L ++C +P RP+F I L ++ Sbjct 320 SNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEIR 373 >sp|Q61006|MUSK_MOUSE Muscle, skeletal receptor tyrosine-protein kinase OS=Mus musculus OX=10090 GN=Musk PE=1 SV=1 Length=868 Score = 137 bits (345), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 89/318 (28%), Positives = 154/318 (48%), Gaps = 53/318 (17%) Query 892 FHKRYLKKIRDLGEGHFGKV------SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 + + ++ +RD+GEG FG+V L Y+P MVAVK LK + ++ ++ Sbjct 569 YPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFT-----MVAVKMLKEEASADMQADFQ 623 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------- 994 +E ++ + +I+K G C K + L+ EY+ G L ++L S Sbjct 624 REAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSD 681 Query 995 --------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040 + A+ L A+Q+ GMAYL + ++HRDLA RN L+ +VKI Sbjct 682 LSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGETMVVKIA 741 Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100 DFGL++ + +YY+ + P+ W PE + ++ SDVW++GV L+E+ ++ Sbjct 742 DFGLSRNIYSA-DYYKADGNDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSY--- 797 Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 G+A ++ + G L P+ CP E+Y+LM+ CW + RP Sbjct 798 ------GLQPYYGMAHEEVIY-----YVRDGNILACPENCPLELYNLMRLCWSKLPADRP 846 Query 1161 TFENLIPILKTVHEKYQG 1178 +F ++ IL+ + E+ +G Sbjct 847 SFCSIHRILQRMCERAEG 864 Score = 77.4 bits (189), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 67/263 (25%), Positives = 120/263 (46%), Gaps = 41/263 (16%) Query 639 VVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V +K+L + + D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+ Sbjct 605 VAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNE 664 Query 698 WLRRERGH-----------------------VPMAWKMVVAQQLASALSYLENKNLVHGN 734 +LR H + A ++ +A+Q+A+ ++YL + VH + Sbjct 665 FLRSMSPHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRD 724 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGGA 788 + RN L+ G + +K++D G+ S + + + IP W+ PE + Sbjct 725 LATRNCLV-------GETMVVKIADFGLSRNIYSADYYKADGNDAIPIRWMPPESI--FY 775 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTS 846 N +T D W +G L EI G P + E ++ + + L P +CP +L L Sbjct 776 NRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILACPENCPLELYNLMR 835 Query 847 QCLTYEPTQRPSFRTILRDLTRL 869 C + P RPSF +I R L R+ Sbjct 836 LCWSKLPADRPSFCSIHRILQRM 858 >sp|Q91694|EPA4B_XENLA Ephrin type-A receptor 4-B OS=Xenopus laevis OX=8355 GN=epha4-b PE=2 SV=1 Length=985 Score = 137 bits (345), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 89/294 (30%), Positives = 148/294 (50%), Gaps = 31/294 (11%) Query 888 DPTVFHKRYLKKI--------RDLGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCG 937 DP + + K+I + +G G FG+V C G E+ VA+K LKA Sbjct 603 DPNQAVREFAKEIDASCIKIEKVIGVGEFGEV---CSGRLKVPGKREIYVAIKTLKAGYT 659 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995 + R + E I+ H +II +G K + ++ EY+ GSL +L ++ Sbjct 660 DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKC--KPVMIITEYMENGSLDAFLRKNDGRF 717 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFG+++ + + E Sbjct 718 TVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAA 777 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 G P+ W APE + KF ASDVWS+G+ ++E++++ + P Sbjct 778 YTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY---GERP----------- 823 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 M+ + + +E G RLP P CP ++ LM +CW+ + S RP F ++ +L Sbjct 824 YWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKDRSDRPKFGQIVSML 877 Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 73/259 (28%), Positives = 121/259 (47%), Gaps = 24/259 (9%) Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 VPG+ +E+ V +K L + D F AS+M Q H ++ + GV + +++ Sbjct 641 VPGK---REIYVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMII 697 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TEY+E+G LD +LR+ G + + + + + S + YL + + VH ++ RNIL+ Sbjct 698 TEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILV---- 753 Query 747 LAEGTSPFIKLSDPGVGLGALSREE-----RVERIP--WLAPECLPGGANSLSTAMDKWG 799 ++ K+SD G+ E R +IP W APE + ++A D W Sbjct 754 ---NSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAI--AYRKFTSASDVWS 808 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRP 857 +G + E+ GE P S + + +RLP P CP L L C + + RP Sbjct 809 YGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKDRSDRP 868 Query 858 SFRTILRDLTRL--QPHNL 874 F I+ L +L P++L Sbjct 869 KFGQIVSMLDKLIRNPNSL 887 >sp|H2KZU7|SVH2_CAEEL Tyrosine-protein kinase receptor svh-2 OS=Caenorhabditis elegans OX=6239 GN=svh-2 PE=1 SV=1 Length=1086 Score = 137 bits (345), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 94/290 (32%), Positives = 142/290 (49%), Gaps = 20/290 (7%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 F + K+ +G+GH+G V Y P+ E V K LK S + +E + Sbjct 730 FKNLRVDKLDPIGQGHYGVVYKAMYSPSK-SLEEKVVCKYLKEG----KISEFYEEARTM 784 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICE 1009 H +I+K G D ++ EY+ G L+ ++ ++I + L FA I + Sbjct 785 SEFDHPNILKLIGVALDDSSHLPIIITEYMAKGDLKSFIENVENTIKMRDLFEFAFDIAK 844 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 GM Y+H++ +IHRDLA RN LLD VKI DFGL + V E Y + D PV W+ Sbjct 845 GMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERDLPVRWFP 904 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE + E F SD+WSFGV ++EL T +P + I I + L+ +E Sbjct 905 PE-ISEQGFGITSDIWSFGVVIWELFTR---GSTPYSNMASWILI----LPWLKESET-- 954 Query 1130 RGERLPRPDKCPCEVY-HLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 RL +P CP ++Y +M CW+ + RP F +L+ I+ V + +G Sbjct 955 --NRLRKPPYCPEKLYTDVMLACWKANPAERPQFSDLVTIIPNVVKYMEG 1002 Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 57/236 (24%), Positives = 90/236 (38%), Gaps = 35/236 (15%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN--IMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 FYE A MS+ H ++ + GV + + I++TEY+ G L ++ + M Sbjct 777 FYEEARTMSEFDHPNILKLIGVALDDSSHLPIIITEYMAKGDLKSFIENVENTIKMRDLF 836 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPGVGL 764 A +A ++Y+ +K +H ++ RN LL A GL +L Sbjct 837 EFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETEL------- 889 Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS----- 819 + ER + W PE G D W FG + E+ G P + + Sbjct 890 -YVQMHERDLPVRWFPPEISEQG---FGITSDIWSFGVVIWELFTRGSTPYSNMASWILI 945 Query 820 -PSEKEHFYQRQHRLPEPSCPQ--LATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 P KE R + P CP+ + C P +RP F DL + P+ Sbjct 946 LPWLKESETNRLRK--PPYCPEKLYTDVMLACWKANPAERPQF----SDLVTIIPN 995 >sp|P08630|BTKL_DROME Tyrosine-protein kinase Btk OS=Drosophila melanogaster OX=7227 GN=Btk PE=2 SV=2 Length=786 Score = 136 bits (343), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 104/323 (32%), Positives = 152/323 (47%), Gaps = 40/323 (12%) Query 865 DLTRLQPHN---LADVLTVNP-DSP-------ASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 DL HN LA L +P D P + D H L + +LG G FG V Sbjct 483 DLINYHRHNSGGLACRLKSSPCDRPVPPTAGLSHDKWEIHPMELMLMEELGSGQFGVVRR 542 Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 + + D AVK +K G + +E ++ L H ++++ G C + Sbjct 543 GKWRGSID-----TAVKMMKE--GTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKH--RP 593 Query 974 LQLVMEYVPLGSLRDYLPRHS---IGLAQLLL-FAQQICEGMAYLHAQHYIHRDLAARNV 1029 + +V EY+ GSL +YL RH IG LLL Q+ +GM YL +YIHRDLAARN Sbjct 594 IYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNC 653 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 L+ ++ +VK+ DFGLA+ V + + Y P+ W PE L +F SDVW++GV Sbjct 654 LVGSENVVKVADFGLARYVLD--DQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGV 711 Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149 ++E+ T C + G++ + E ++RG L +P C E+Y +MK Sbjct 712 LMWEIFT-CGK-------------MPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMK 757 Query 1150 NCWETEASFRPTFENLIPILKTV 1172 CW RP F L+ L V Sbjct 758 LCWSHGPEERPAFRVLMDQLALV 780 Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 66/233 (28%), Positives = 110/233 (47%), Gaps = 23/233 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER----GHVPMAW 710 F E A +M+++ H +L ++GVC + +VTEY++HG L +LRR G++ + Sbjct 566 FIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLL 625 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 M + Q++ ++YLE N +H ++ RN L+ G+ +K++D G+ L + Sbjct 626 DMCI--QVSKGMTYLERHNYIHRDLAARNCLV-------GSENVVKVADFGLARYVLDDQ 676 Query 771 ERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 I W PE L S+ D W +G + EI G+ P +E Sbjct 677 YTSSGGTKFPIKWAPPEVL--NYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVE 734 Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 QR L +P SC ++ + C ++ P +RP+FR +L D L L D Sbjct 735 RVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFR-VLMDQLALVAQTLTD 786 >sp|Q54I36|PYK3_DICDI Dual specificity protein kinase pyk3 OS=Dictyostelium discoideum OX=44689 GN=pyk3 PE=1 SV=1 Length=1338 Score = 137 bits (345), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 130/547 (24%), Positives = 234/547 (43%), Gaps = 71/547 (13%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S + + H +L + G C ++I+ + L + R+ + MA + +++ +A Sbjct 809 SKYTMIQHKNLGLLVGWC---GDSIIFESFKGMNSLHDLIHRDGLKIDMALFIKISKDIA 865 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL 779 S + L +K++ HGN+ R+I L R + + + P + +D L + E R ++ Sbjct 866 SVMGLLHSKDVAHGNLTSRSIYLDRFQIVKVSFPKLNATD----LNNPAIEPR-----YM 916 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ---SRSPSEKEHFYQRQHRLPEP 836 APE + +S ++D + + L E P + S + K + + ++P Sbjct 917 APEMTRMEEDQISCSIDVYAYAFVLWE-ALTSHLPFRKFNDISVAAKVAYENLRPKIP-T 974 Query 837 SCPQLA-TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD----VLTVNPDSPASDPTV 891 SCP + L ++C P+ RP+F IL+ L+ + ++N D Sbjct 975 SCPLIIRKLINRCWAPLPSDRPTFNDILKLFDHLEGKLFFSSPGILWSLNNDQEVERELQ 1034 Query 892 FHKRY-----------------LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 +R+ + + +G G F V L ++ G VA+K LK Sbjct 1035 KKERFNEITEFLRGKKEIKFDEVAIVEKVGAGSFANVFLGIWN------GYKVAIKILKN 1088 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994 + + + +E+ L +H +++ + G C D + EY+ GSL D L Sbjct 1089 E-SISNDEKFIKEVSSLIKSHHPNVVTFMGACIDPP----CIFTEYLQGGSLYDVLHIQK 1143 Query 995 IGLAQLLLFA--QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 I L L+++ + GM +LH+ +HRDL ++N+LLD + +KI DFGLA + + Sbjct 1144 IKLNPLMMYKMIHDLSLGMEHLHSIQMLHRDLTSKNILLDEFKNIKIADFGLATTLSDD- 1202 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 + G + W +PE K + DV+SFG+ +YE+ T F L Sbjct 1203 ----MTLSGITNPRWRSPELTKGLVYNEKVDVYSFGLVVYEIYTG-------KIPFEGLD 1251 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 G A R P CP + L+ CW ++ S RP+F ++ L+T+ Sbjct 1252 GTASAAKAAF-------ENYRPAIPPDCPVSLRKLITKCWASDPSQRPSFTEILTELETM 1304 Query 1173 HEKYQGQ 1179 K+ Q Sbjct 1305 KSKFIKQ 1311 Score = 67.0 bits (162), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 67/260 (26%), Positives = 120/260 (46%), Gaps = 30/260 (12%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-D 696 +V +K+L F + S + + H ++ G C+ P + TEY++ G L D Sbjct 1080 KVAIKILKNESISNDEKFIKEVSSLIKSHHPNVVTFMGACIDPP--CIFTEYLQGGSLYD 1137 Query 697 VW-LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 V +++ + + M +KM+ L+ + +L + ++H ++ +NILL I Sbjct 1138 VLHIQKIKLNPLMMYKMI--HDLSLGMEHLHSIQMLHRDLTSKNILLDEFK-------NI 1188 Query 756 KLSDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 K++D G+ LS + + I W +PE G + +D + FG + EI + G+ Sbjct 1189 KIADFGLA-TTLSDDMTLSGITNPRWRSPELTKGLV--YNEKVDVYSFGLVVYEI-YTGK 1244 Query 813 AP---LQSRSPSEKEHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTR 868 P L + + K F + +P P CP L L ++C +P+QRPSF IL +L Sbjct 1245 IPFEGLDGTASAAKAAFENYRPAIP-PDCPVSLRKLITKCWASDPSQRPSFTEILTELET 1303 Query 869 LQPH-----NLADVLTVNPD 883 ++ + + L NPD Sbjct 1304 MKSKFIKQLSFLNDLIQNPD 1323 Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 52/210 (25%), Positives = 91/210 (43%), Gaps = 35/210 (17%) Query 983 LGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040 + SL D + R I +A + ++ I M LH++ H +L +R++ LD ++VK+ Sbjct 838 MNSLHDLIHRDGLKIDMALFIKISKDIASVMGLLHSKDVAHGNLTSRSIYLDRFQIVKVS 897 Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVF---WYAPEC--LKEYKFYYASDVWSFGVTLYELL 1095 F A D ++P + APE ++E + + DV+++ L+E L Sbjct 898 -FPKLNAT-----------DLNNPAIEPRYMAPEMTRMEEDQISCSIDVYAYAFVLWEAL 945 Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR-PDKCPCEVYHLMKNCWET 1154 T S P KF ++ A+ LR P+ P CP + L+ CW Sbjct 946 T----SHLPFRKFNDISVAAKVAYENLR-----------PKIPTSCPLIIRKLINRCWAP 990 Query 1155 EASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 S RPTF +++ + + K +P + Sbjct 991 LPSDRPTFNDILKLFDHLEGKLFFSSPGIL 1020 >sp|P15127|INSR_RAT Insulin receptor OS=Rattus norvegicus OX=10116 GN=Insr PE=1 SV=1 Length=1383 Score = 137 bits (345), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 91/285 (32%), Positives = 148/285 (52%), Gaps = 33/285 (12%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +R+LG+G FG V Y + + GE+ VAVK + + R + E +++ Sbjct 1027 LRELGQGSFGMV--YEGNAKDIIKGEVETRVAVKTVNESASLRERIEFLNEASVMKGFTC 1084 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------PRHSIGLAQLLLFAQ 1005 H+++ G +G+ +L +VME + G L+ +L R L +++ Sbjct 1085 HHVVRLLGVVS-KGQPTL-VVMELMAHGDLKSHLRSLRPDAENNPGRPPPTLQEMIQMTA 1142 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 +I +GMAYL+A+ ++HRDLAARN ++ +D VKIGDFG+ + + E +YYR G PV Sbjct 1143 EIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYET-DYYRKGGKGLLPV 1201 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 W +PE LK+ F +SD+WSFGV L+E+ + + G++ Q + Sbjct 1202 RWMSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQ---------GLSNEQ-----VL 1247 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + + G L PD CP + LM+ CW+ RPTF ++ +LK Sbjct 1248 KFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLK 1292 Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 79/301 (26%), Positives = 127/301 (42%), Gaps = 46/301 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +++IT L LGQG+ VYEG + D +G++ E RV +K Sbjct 1019 VPREKITLLRELGQGSFGMVYEGNAK-----DIIKGEV--------------ETRVAVKT 1059 Query 644 LDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 ++ S + F AS+M + H+ + GV +G ++V E + HG L LR Sbjct 1060 VNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSL 1119 Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 R P +M+ + ++A ++YL K VH ++ RN ++A Sbjct 1120 RPDAENNPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAH-------DF 1172 Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+ D G+ + + + + W++PE L G + + D W FG L EI Sbjct 1173 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTASSDMWSFGVVLWEI 1230 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRD 865 E P Q S + F L P +CP+ L L C + P RP+F I+ Sbjct 1231 TSLAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNL 1290 Query 866 L 866 L Sbjct 1291 L 1291 >sp|P15208|INSR_MOUSE Insulin receptor OS=Mus musculus OX=10090 GN=Insr PE=1 SV=2 Length=1372 Score = 137 bits (345), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 90/283 (32%), Positives = 144/283 (51%), Gaps = 29/283 (10%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 +R+LG+G FG V G E VAVK + + R + E +++ H Sbjct 1016 LRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHH 1075 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------PRHSIGLAQLLLFAQQI 1007 +++ G +G+ +L +VME + G L+ +L R L +++ +I Sbjct 1076 VVRLLGVVS-KGQPTL-VVMELMAHGDLKSHLRSLRPDAENNPGRPPPTLQEMIQMTAEI 1133 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 +GMAYL+A+ ++HRDLAARN ++ +D VKIGDFG+ + + E +YYR G PV W Sbjct 1134 ADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYET-DYYRKGGKGLLPVRW 1192 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 +PE LK+ F +SD+WSFGV L+E+ + + G++ Q + + Sbjct 1193 MSPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQ---------GLSNEQ-----VLKF 1238 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + G L PD CP + LM+ CW+ RPTF ++ +LK Sbjct 1239 VMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNLLK 1281 Score = 81.6 bits (200), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 78/301 (26%), Positives = 124/301 (41%), Gaps = 46/301 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +++IT L LGQG+ VYEG + G+ E RV +K Sbjct 1008 VPREKITLLRELGQGSFGMVYEGNAKDIIKGE-------------------AETRVAVKT 1048 Query 644 LDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 ++ S + F AS+M + H+ + GV +G ++V E + HG L LR Sbjct 1049 VNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSL 1108 Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 R P +M+ + ++A ++YL K VH ++ RN ++A Sbjct 1109 RPDAENNPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAH-------DF 1161 Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+ D G+ + + + + W++PE L G + + D W FG L EI Sbjct 1162 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTASSDMWSFGVVLWEI 1219 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRD 865 E P Q S + F L P +CP+ L L C + P RP+F I+ Sbjct 1220 TSLAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNL 1279 Query 866 L 866 L Sbjct 1280 L 1280 >sp|P42687|SPK1_GIRTI Tyrosine-protein kinase SPK-1 OS=Girardia tigrina OX=6162 PE=2 SV=1 Length=497 Score = 133 bits (334), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 87/272 (32%), Positives = 134/272 (49%), Gaps = 31/272 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + ++G G FG V + G VA K L++ R + E I+ L H I Sbjct 223 LNEIGRGFFGSVHRAKW-----GRSYEVAAKMLQS--SKAEREKFVLEAKIMHKLRHRKI 275 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHA 1016 ++ G C + + + +++EY+ GSL++YL L Q++ +I EGMAYL + Sbjct 276 VELLGVCTEPQDMPMLIIVEYMKNGSLKEYLKTPDGKKTNLNQMVHMMAEISEGMAYLES 335 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + +HRDL A N+L+ ND K+ DFGL + + +G + ++ P W APE K Sbjct 336 EKVVHRDLRADNILVANDLTRKVADFGLTE-LTDGSLGDQEKKTLRFPYKWTAPEAAKSK 394 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 F SDVWS+G+ ++E+LT SS P E+I E + +G R+P Sbjct 395 VFTSKSDVWSYGIVMFEILTWA-SSPYPDIPAKEVI-------------EKVSKGYRMPN 440 Query 1137 PDK------CPCEVYHLMKNCWETEASFRPTF 1162 P+K CP E+Y +M CW+ RPTF Sbjct 441 PEKFITGVCCPDEIYKIMIWCWDANPEKRPTF 472 Score = 73.9 bits (180), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 64/264 (24%), Positives = 119/264 (45%), Gaps = 29/264 (11%) Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN---IMVTEYV 690 G+ V K+L S + F A +M ++ H + + GVC P++ +++ EY+ Sbjct 240 GRSYEVAAKMLQSSKAERE-KFVLEAKIMHKLRHRKIVELLGVCTE-PQDMPMLIIVEYM 297 Query 691 EHGPLDVWLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 ++G L +L+ G +MV + +++ ++YLE++ +VH ++ NIL+A L Sbjct 298 KNGSLKEYLKTPDGKKTNLNQMVHMMAEISEGMAYLESEKVVHRDLRADNILVAN-DLTR 356 Query 750 GTSPF--IKLSDPGVGLGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLL 805 + F +L+D +G +E++ R P W APE + ++ D W +G + Sbjct 357 KVADFGLTELTDGSLG----DQEKKTLRFPYKWTAPEA--AKSKVFTSKSDVWSYGIVMF 410 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------CP-QLATLTSQCLTYEPTQRP 857 EI +P E + +R+P P CP ++ + C P +RP Sbjct 411 EILTWASSPYPDIPAKEVIEKVSKGYRMPNPEKFITGVCCPDEIYKIMIWCWDANPEKRP 470 Query 858 SFRTILRDLTRLQPHNLADVLTVN 881 +F + + L + D LT N Sbjct 471 TFLVLQEKMDLL----IVDTLTNN 490 >sp|P57097|MERTK_RAT Tyrosine-protein kinase Mer OS=Rattus norvegicus OX=10116 GN=Mertk PE=2 SV=1 Length=994 Score = 136 bits (343), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 93/288 (32%), Positives = 140/288 (49%), Gaps = 29/288 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEI 948 V + L + LGEG FG V + DGT + VAVK +K D + + E Sbjct 575 VVVDRNLLILGKVLGEGEFGSV-MEGNLKQEDGTSQKVAVKTMKLDNFSLREIEEFLSEA 633 Query 949 DILRTLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGSLRDYL--------PRHSIGL 997 ++ H ++I+ G C QG +++ ++ G L +L P+ SI L Sbjct 634 ACMKDFNHPNVIRLLGVCIELSSQGIPKPMVILPFMKYGDLHTFLLYSRIESVPK-SIPL 692 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 LL F I +GM YL +++++HRDLAARN +L +D V + DFGL+K + G +YYR Sbjct 693 QTLLKFMVDIAQGMEYLSSRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQ 751 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 PV W A E L + + SDVW+FGVT++E+ T G+ Sbjct 752 GRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATR---------GMTPYPGVQNH 802 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 +M + L G RL +P+ C ++Y +M +CW + RPTF L Sbjct 803 EM-----YDYLLHGHRLKQPEDCLDDLYEIMYSCWSADPLDRPTFSVL 845 Score = 69.7 bits (169), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 73/309 (24%), Positives = 130/309 (42%), Gaps = 38/309 (12%) Query 606 GRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI--ALAFYETASLM 662 G++ EG G EG + ED G +V +K + + + F A+ M Sbjct 585 GKVLGEGEFGSVMEGNLKQED--------GTSQKVAVKTMKLDNFSLREIEEFLSEAACM 636 Query 663 SQVSHTHLAFVHGVCVR-----GPENIMVTEYVEHGPLDVWLRRER-----GHVPMAWKM 712 +H ++ + GVC+ P+ +++ ++++G L +L R +P+ + Sbjct 637 KDFNHPNVIRLLGVCIELSSQGIPKPMVILPFMKYGDLHTFLLYSRIESVPKSIPLQTLL 696 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 +A + YL ++N +H ++ RN +L R + + F LS + G R+ R Sbjct 697 KFMVDIAQGMEYLSSRNFLHRDLAARNCML-RDDMTVCVADF-GLSKK-IYSGDYYRQGR 753 Query 773 VERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 + ++P W+A E L ++ D W FG T+ EI G P E + Sbjct 754 IAKMPVKWIAIESL--ADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLHG 811 Query 831 HRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASD 888 HRL PE L + C + +P RP+F + RLQ L++ L PD+ + Sbjct 812 HRLKQPEDCLDDLYEIMYSCWSADPLDRPTFSVL-----RLQLEKLSESL---PDAQDKE 863 Query 889 PTVFHKRYL 897 ++ L Sbjct 864 SIIYINTQL 872 >sp|Q63132|ROS1_RAT Proto-oncogene tyrosine-protein kinase ROS OS=Rattus norvegicus OX=10116 GN=Ros1 PE=2 SV=1 Length=2338 Score = 137 bits (345), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 96/261 (37%), Positives = 135/261 (52%), Gaps = 37/261 (14%) Query 922 GTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC---EDQGEKSLQLV 977 G+GE+ VAVK LK Q + + +E ++ H +I+K G C E Q ++ Sbjct 1963 GSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLSEPQ-----YII 2017 Query 978 MEYVPLGSLRDYLPRHS--------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029 +E + G L YL + + LA L+ I +G YL H+IHRDLAARN Sbjct 2018 LELMEGGDLLSYLRKARGTTLSGPLLTLADLVELCVDISKGCVYLEQMHFIHRDLAARNC 2077 Query 1030 LLD-----NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084 L+ + R+VKIGDFGLA+ + + H+YYR R +G PV W APE L + F SDV Sbjct 2078 LVSVKDYTSPRVVKIGDFGLAREIYK-HDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDV 2136 Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144 WSFG+ ++E+LT Q P A + VL ++ G RL P CP ++ Sbjct 2137 WSFGILVWEILTL--GHQPYP---------AHSNLDVLN---YVQAGGRLEPPRNCPDDL 2182 Query 1145 YHLMKNCWETEASFRPTFENL 1165 ++LM CW E RPTF N+ Sbjct 2183 WNLMFRCWAQEPDQRPTFYNI 2203 Score = 87.0 bits (214), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 80/289 (28%), Positives = 132/289 (46%), Gaps = 26/289 (9%) Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAF 672 G+ EG D + GR G E++V +K L D + F + A LMS+ +H ++ Sbjct 1949 GEVYEGTAVD----ILGRGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILK 2003 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH------VPMAWKMVVAQQLASALSYLE 726 GVC+ ++ E +E G L +LR+ RG + +A + + ++ YLE Sbjct 2004 QLGVCLLSEPQYIILELMEGGDLLSYLRKARGTTLSGPLLTLADLVELCVDISKGCVYLE 2063 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSP-FIKLSDPGVGLGALSREERVER------IPWL 779 + +H ++ RN L++ + + TSP +K+ D G+ + +R + W+ Sbjct 2064 QMHFIHRDLAARNCLVS---VKDYTSPRVVKIGDFGLAREIYKHDYYRKRGEGLLPVRWM 2120 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838 APE L G ++ D W FG + EI G P + S + ++ Q RL P +C Sbjct 2121 APENLMDGI--FTSQSDVWSFGILVWEILTLGHQPYPAHSNLDVLNYVQAGGRLEPPRNC 2178 Query 839 P-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 P L L +C EP QRP+F I L + +L +V +PA Sbjct 2179 PDDLWNLMFRCWAQEPDQRPTFYNIQDQLQLFRNVSLNNVSHCGQAAPA 2227 >sp|Q64716|INSRR_RAT Insulin receptor-related protein OS=Rattus norvegicus OX=10116 GN=Insrr PE=1 SV=3 Length=1300 Score = 136 bits (343), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 94/283 (33%), Positives = 147/283 (52%), Gaps = 37/283 (13%) Query 900 IRDLGEGHFGKVSLYCYDPTNDG--TGEM---VAVKALKADCGPQHRSGWKQEIDILRTL 954 IR+LG+G FG V Y+ G GE VA+K + + R + +E +++ Sbjct 982 IRELGQGSFGMV----YEGLARGLEAGEESTPVALKTVNELASARERVEFLKEASVMKAF 1037 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQ-----LLLF 1003 H+++ G QG+ +L ++ME + G L+ +L ++ GL Q ++ Sbjct 1038 KCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSHLRSLRPEAENNPGLPQPALSDMIQM 1095 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 A +I +GMAYL A+ ++HRDLAARN ++ D VKIGDFG+ + V E +YYR G Sbjct 1096 AGEIADGMAYLAAKKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYE-TDYYRKGGKGLL 1154 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 PV W APE LK+ F SDVWSFGV L+E++T + G++ Q+ Sbjct 1155 PVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQ---------GLSNEQV---- 1201 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + + G L + CP ++ LM+ CW+ RPTF +++ Sbjct 1202 -LKFVMDGGVLEEQEDCPIQLQELMRRCWQHTPRLRPTFVHIL 1243 Score = 73.9 bits (180), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 76/298 (26%), Positives = 121/298 (41%), Gaps = 46/298 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLR-VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 V +++I + LGQG+ VYEG R +E + + + L R+R Sbjct 974 VPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASARER--------- 1024 Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 + F + AS+M H+ + GV +G +++ E + G L LR Sbjct 1025 ----------VEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSL 1074 Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 R P M+ +A ++A ++YL K VH ++ RN ++++ Sbjct 1075 RPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQ-------DF 1127 Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+ D G+ + + + + W+APE L G +T D W FG L EI Sbjct 1128 TVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGI--FTTHSDVWSFGVVLWEI 1185 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSFRTIL 863 E P Q S + F L E CP QL L +C + P RP+F IL Sbjct 1186 VTLAEQPYQGLSNEQVLKFVMDGGVLEEQEDCPIQLQELMRRCWQHTPRLRPTFVHIL 1243 >sp|Q06187|BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo sapiens OX=9606 GN=BTK PE=1 SV=3 Length=659 Score = 134 bits (338), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 89/279 (32%), Positives = 140/279 (50%), Gaps = 28/279 (10%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +++LG G FG V + D VA+K +K G + +E ++ L HE + Sbjct 405 LKELGTGQFGVVKYGKWRGQYD-----VAIKMIKE--GSMSEDEFIEEAKVMMNLSHEKL 457 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ 1017 ++ G C Q + + ++ EY+ G L +YL RH QLL + +CE M YL ++ Sbjct 458 VQLYGVCTKQ--RPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESK 515 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 ++HRDLAARN L+++ +VK+ DFGL++ V + Y PV W PE L K Sbjct 516 QFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDE--YTSSVGSKFPVRWSPPEVLMYSK 573 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SD+W+FGV ++E+ + L + + T E + +G RL RP Sbjct 574 FSSKSDIWAFGVLMWEIYS--------------LGKMPYERFTNSETAEHIAQGLRLYRP 619 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP-ILKTVHEK 1175 +VY +M +CW +A RPTF+ L+ IL + E+ Sbjct 620 HLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 658 Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 81/317 (26%), Positives = 137/317 (43%), Gaps = 55/317 (17%) Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP-----E 617 + + + +P T L S+ +D K++T L LG G V G+ R G D + Sbjct 377 VSQQNKNAPSTAGLGYGSWE-IDPKDLTFLKELGTGQFGVVKYGKWR--GQYDVAIKMIK 433 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 EG M +++ F E A +M +SH L ++GVC Sbjct 434 EGSMSEDE-----------------------------FIEEAKVMMNLSHEKLVQLYGVC 464 Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737 + ++TEY+ +G L +LR R + + + + A+ YLE+K +H ++ Sbjct 465 TKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAA 524 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV---ERIP--WLAPECLPGGANSLS 792 RN L+ G+ +K+SD G+ L E + P W PE L + S Sbjct 525 RNCLVNDQGV-------VKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVL--MYSKFS 575 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQ--RQHRLPEPSCPQLATLTSQCL 849 + D W FG + EI G+ P + + SE EH Q R +R P + ++ T+ C Sbjct 576 SKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYR-PHLASEKVYTIMYSCW 634 Query 850 TYEPTQRPSFRTILRDL 866 + +RP+F+ +L ++ Sbjct 635 HEKADERPTFKILLSNI 651 >sp|P13368|7LESS_DROME Protein sevenless OS=Drosophila melanogaster OX=7227 GN=sev PE=1 SV=2 Length=2554 Score = 137 bits (344), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 94/295 (32%), Positives = 139/295 (47%), Gaps = 38/295 (13%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 LK +R LG G FG+V + + VA+K+L+ G + QE ++ H Sbjct 2209 LKLLRFLGSGAFGEVYEGQLKTEDSEEPQRVAIKSLRK--GASEFAELLQEAQLMSNFKH 2266 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------------PRHSIGLAQLLLFA 1004 E+I+ G C D +S+ L+ME++ G L YL P + L++LL Sbjct 2267 ENIVCLVGICFDT--ESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMC 2324 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLL-------DNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + G +YL H++HRDLA RN L+ D R VKIGDFGLA+ + + +YYR Sbjct 2325 IDVANGCSYLEDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKS-DYYRK 2383 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 +G PV W +PE L + F SDVW+FGV +E+LT + F L + +G Sbjct 2384 EGEGLLPVRWMSPESLVDGLFTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEG 2443 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 RL +P C ++Y L+ CW T+ RP+F L + Sbjct 2444 G--------------RLQQPPMCTEKLYSLLLLCWRTDPWERPSFRRCYNTLHAI 2484 Score = 84.7 bits (208), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 86/340 (25%), Positives = 143/340 (42%), Gaps = 49/340 (14%) Query 557 ETSNLIIMRGARASPRTLNLSQLSF-HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615 +T ++ RA TL+ + ++ +++ ++ L LG G VYEG+L+ E S + Sbjct 2176 QTQQQLMAVRNRAFSTTLSDADIALLPQINWSQLKLLRFLGSGAFGEVYEGQLKTEDSEE 2235 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675 P+ RV +K L + A E A LMS H ++ + G Sbjct 2236 PQ--------------------RVAIKSLRKGASEFAELLQE-AQLMSNFKHENIVCLVG 2274 Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRERGH----------VPMAWKMVVAQQLASALSYL 725 +C ++ E++E G L +LR R + ++ + + +A+ SYL Sbjct 2275 ICFDTESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMCIDVANGCSYL 2334 Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WL 779 E+ + VH ++ RN L+ + +K+ D G+ R+E +P W+ Sbjct 2335 EDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDYYRKEGEGLLPVRWM 2394 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--S 837 +PE L G +T D W FG EI G+ P +R+ E + RL +P Sbjct 2395 SPESLVDGL--FTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEGGRLQQPPMC 2452 Query 838 CPQLATLTSQCLTYEPTQRPSFR-------TILRDLTRLQ 870 +L +L C +P +RPSFR I DL R Q Sbjct 2453 TEKLYSLLLLCWRTDPWERPSFRRCYNTLHAISTDLRRTQ 2492 >sp|Q25197|HTK7_HYDVU Putative insulin-like peptide receptor OS=Hydra vulgaris OX=6087 GN=HTK7 PE=2 SV=1 Length=1477 Score = 136 bits (343), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 100/312 (32%), Positives = 153/312 (49%), Gaps = 42/312 (13%) Query 879 TVNPDSPAS------DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE----MVA 928 +VNP+ S D ++ ++ IR+LG+G FG V ++ G G+ VA Sbjct 1020 SVNPEYMNSKEVYIPDEWELNREKIELIRELGQGSFGMV----FEGIAHGIGDHAELRVA 1075 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 VK + R QE I++ H++K G QG+ + +VME + G L+ Sbjct 1076 VKTTNENASIHDRIQILQEASIMKAFNCNHVVKLIGVVS-QGQPTF-VVMELMGRGDLKS 1133 Query 989 YLPRHS-------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 YL + ++ +I +GMAYL A+ ++H DLAARN ++ +D VKIGD Sbjct 1134 YLKERRPDDGGIPLMRQEIYQMVAEIADGMAYLAARKFVHCDLAARNCMVASDFTVKIGD 1193 Query 1042 FGLAKAVPEGHEYYRVREDGDS--PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 FG+A+ + E + Y R+DG S P+ W APE LK+ F ASDVWSFGV L+E+ C Sbjct 1194 FGMARDIYERNYY---RKDGKSLLPIRWMAPESLKDGIFSTASDVWSFGVVLWEI---CT 1247 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 + P QG+ L +L G L P+ C ++ M CW + R Sbjct 1248 LASQP----------YQGKTNEQVLNFVLSNG-HLDYPEGCDYQLREFMSLCWHRDPKMR 1296 Query 1160 PTFENLIPILKT 1171 P+F ++ +L+ Sbjct 1297 PSFLEIVHVLEN 1308 Score = 90.5 bits (223), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 86/319 (27%), Positives = 137/319 (43%), Gaps = 50/319 (16%) Query 567 ARASPRTLNLSQLSF---HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 A +P +N ++ +++++I + LGQG+ V+EG G GD Sbjct 1019 ASVNPEYMNSKEVYIPDEWELNREKIELIRELGQGSFGMVFEGI--AHGIGDH------- 1069 Query 624 EDPLVPGRDRGQELRVVLKVLD--PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 ELRV +K + S HD + + AS+M + H+ + GV +G Sbjct 1070 -----------AELRVAVKTTNENASIHD-RIQILQEASIMKAFNCNHVVKLIGVVSQGQ 1117 Query 682 ENIMVTEYVEHGPLDVWLRRER---GHVPMAWKMV--VAQQLASALSYLENKNLVHGNVC 736 +V E + G L +L+ R G +P+ + + + ++A ++YL + VH ++ Sbjct 1118 PTFVVMELMGRGDLKSYLKERRPDDGGIPLMRQEIYQMVAEIADGMAYLAARKFVHCDLA 1177 Query 737 GRNILLARLGLAEGTSPF-IKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGAN 789 RN ++A S F +K+ D G+ R + + I W+APE L G Sbjct 1178 ARNCMVA--------SDFTVKIGDFGMARDIYERNYYRKDGKSLLPIRWMAPESLKDGI- 1228 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847 STA D W FG L EIC P Q ++ + +F L PE QL S Sbjct 1229 -FSTASDVWSFGVVLWEICTLASQPYQGKTNEQVLNFVLSNGHLDYPEGCDYQLREFMSL 1287 Query 848 CLTYEPTQRPSFRTILRDL 866 C +P RPSF I+ L Sbjct 1288 CWHRDPKMRPSFLEIVHVL 1306 >sp|Q78DX7|ROS1_MOUSE Proto-oncogene tyrosine-protein kinase ROS OS=Mus musculus OX=10090 GN=Ros1 PE=1 SV=1 Length=2340 Score = 137 bits (344), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 95/258 (37%), Positives = 135/258 (52%), Gaps = 31/258 (12%) Query 922 GTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 G+GE+ VAVK LK Q + + +E ++ H +I+K G C GE +++E Sbjct 1964 GSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCL-LGEPQY-IILEL 2021 Query 981 VPLGSLRDYLPRH--------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032 + G L YL + S+ L L+ I +G YL H+IHRDLAARN L+ Sbjct 2022 MEGGDLLSYLRKARGTTFHGPSLTLLDLVELCVDISKGCVYLEQMHFIHRDLAARNCLVS 2081 Query 1033 -----NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 + R+VKIGDFGLA+ + + ++YYR R +G PV W APE L + F SDVWSF Sbjct 2082 VKDYTSPRVVKIGDFGLAREIYK-NDYYRKRGEGLLPVRWMAPENLMDGIFTSQSDVWSF 2140 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 G+ ++E+LT Q P A + VL ++ G RL P CP ++++L Sbjct 2141 GILVWEILTL--GHQPYP---------AHSNLDVLN---YVQAGGRLEPPRNCPDDLWNL 2186 Query 1148 MKNCWETEASFRPTFENL 1165 M CW E RPTF N+ Sbjct 2187 MSQCWAQEPDQRPTFHNI 2204 Score = 90.1 bits (222), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 75/258 (29%), Positives = 121/258 (47%), Gaps = 21/258 (8%) Query 636 ELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 E++V +K L D + F + A LMS+ +H ++ GVC+ G ++ E +E G Sbjct 1967 EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLGEPQYIILELMEGGD 2026 Query 695 LDVWLRRERG---HVPMAWKMVVAQ---QLASALSYLENKNLVHGNVCGRNILLARLGLA 748 L +LR+ RG H P + + + ++ YLE + +H ++ RN L++ + Sbjct 2027 LLSYLRKARGTTFHGPSLTLLDLVELCVDISKGCVYLEQMHFIHRDLAARNCLVS---VK 2083 Query 749 EGTSP-FIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFG 801 + TSP +K+ D G+ + +R + W+APE L G ++ D W FG Sbjct 2084 DYTSPRVVKIGDFGLAREIYKNDYYRKRGEGLLPVRWMAPENLMDGI--FTSQSDVWSFG 2141 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 + EI G P + S + ++ Q RL P +CP L L SQC EP QRP+F Sbjct 2142 ILVWEILTLGHQPYPAHSNLDVLNYVQAGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTF 2201 Query 860 RTILRDLTRLQPHNLADV 877 I L + L +V Sbjct 2202 HNIQNQLQLFRNVFLNNV 2219 >sp|P09760|FER_RAT Tyrosine-protein kinase Fer OS=Rattus norvegicus OX=10116 GN=Fer PE=1 SV=2 Length=823 Score = 135 bits (340), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 92/277 (33%), Positives = 139/277 (50%), Gaps = 29/277 (10%) Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG+G+FG+V Y T D T VAVK K D + + + QE IL+ H +I+K Sbjct 570 LGKGNFGEV----YKGTLKDKTP--VAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVK 623 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHY 1019 G C + + + ++ME VP G +L + + L QL+ F+ + GM YL ++ Sbjct 624 LIGVCTQR--QPVYIIMELVPGGDFLSFLRKRKDELKLKQLVRFSLDVAAGMLYLEGKNC 681 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRDLAARN L+ + +KI DFG+++ G Y P+ W APE L ++ Sbjct 682 IHRDLAARNCLVGENNTLKISDFGMSRQEDGG--VYSSSGLKQIPIKWTAPEALNYGRYS 739 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA-QGQMTVLRLTELLERGERLPRPD 1138 SDVWSFG+ L+E + +G+ MT + E +ERG R+ P Sbjct 740 SESDVWSFGILLWETFS---------------LGVCPYPGMTNQQAREQVERGYRMSAPQ 784 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 CP E++ +M CW+ + RP F +L L + +K Sbjct 785 NCPEEIFTIMMKCWDYKPENRPKFSDLHKELTAIKKK 821 Score = 87.8 bits (216), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 101/434 (23%), Positives = 182/434 (42%), Gaps = 86/434 (20%) Query 449 DGIHGPLLEPFVQAK-LRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPI 507 D HG + P ++A+ L + G +L+ S P +L+V DG + R F I Sbjct 460 DWYHGAI--PRIEAQELLKQQGDFLVRESHGKPGEYVLSVY-----SDGQR----RHFII 508 Query 508 EQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGA 567 + D + EG G F ++ +L D F+ ++ + G ++++ Sbjct 509 QFVDNLYRFEGTG--FSNIPQLI-----------DHHFNTKQVITKKSG----VVLLNPI 551 Query 568 RASPR-TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 + LN +S + LG+G VY+G L+ D+ P Sbjct 552 PKDKKWVLNHEDVSLGEL----------LGKGNFGEVYKGTLK-------------DKTP 588 Query 627 LVPG---RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 + D QEL++ F + A ++ Q H ++ + GVC + Sbjct 589 VAVKTCKEDLPQELKI--------------KFLQEAKILKQYDHPNIVKLIGVCTQRQPV 634 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 ++ E V G +LR+ + + + + + +A+ + YLE KN +H ++ RN L+ Sbjct 635 YIIMELVPGGDFLSFLRKRKDELKLKQLVRFSLDVAAGMLYLEGKNCIHRDLAARNCLV- 693 Query 744 RLGLAEGTSPFIKLSDPGVGL---GALSREERVERIP--WLAPECLPGGANSLSTAMDKW 798 G + +K+SD G+ G + +++IP W APE L G S+ D W Sbjct 694 ------GENNTLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYG--RYSSESDVW 745 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQR 856 FG L E G P + + +R +R+ P +CP ++ T+ +C Y+P R Sbjct 746 SFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQNCPEEIFTIMMKCWDYKPENR 805 Query 857 PSFRTILRDLTRLQ 870 P F + ++LT ++ Sbjct 806 PKFSDLHKELTAIK 819 >sp|P20806|7LESS_DROVI Protein sevenless OS=Drosophila virilis OX=7244 GN=sev PE=3 SV=1 Length=2594 Score = 137 bits (344), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 90/291 (31%), Positives = 141/291 (48%), Gaps = 34/291 (12%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L +R LG G FG+V ++ + VA+K+L+ G + QE ++ H Sbjct 2224 LTLLRFLGSGAFGEVYEGQLQAEDEAQPQRVAIKSLRK--GASEFAELLQEAQLMSNFKH 2281 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---------PRHSIGLAQLLLFAQQI 1007 E+I+ G C D S+ L+ME++ G L YL + L +LL + Sbjct 2282 ENIVCLIGICCD--TDSISLIMEHMEAGDLLSYLRAARPSSQEALSKLQLPELLSMCLDV 2339 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDND------RLVKIGDFGLAKAVPEGHEYYRVREDG 1061 G +Y+ H++HRDLA RN L+ + R+VKIGDFGLA+ + + +YYR +G Sbjct 2340 ANGCSYMEDMHFVHRDLACRNCLVSDGAAIGGRRIVKIGDFGLARDIYKS-DYYRKEGEG 2398 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 PV W A E L + F SDVW+FGV +E+ T + F L + +G Sbjct 2399 LLPVRWMALESLVDGLFSTQSDVWAFGVLCWEIFTLGQQPYAARNNFEVLAHVKEGG--- 2455 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 RL +P++CP ++Y L+ CW +E RP+F+ + L+ + Sbjct 2456 -----------RLQQPERCPEKLYALLLQCWRSEPWERPSFKRCLSTLQAL 2495 Score = 91.3 bits (225), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 88/324 (27%), Positives = 139/324 (43%), Gaps = 42/324 (13%) Query 564 MRGARASPRTLNLSQLSFH---RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620 + AR+ +++LS +++ +T L LG G VYEG+L+ E P+ Sbjct 2196 LLAARSRTFSMSLSDADIALLPQINWNRLTLLRFLGSGAFGEVYEGQLQAEDEAQPQ--- 2252 Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680 RV +K L + A + A LMS H ++ + G+C Sbjct 2253 -----------------RVAIKSLRKGASEFA-ELLQEAQLMSNFKHENIVCLIGICCDT 2294 Query 681 PENIMVTEYVEHGPLDVWLRRER-------GHVPMAWKMVVAQQLASALSYLENKNLVHG 733 ++ E++E G L +LR R + + + + +A+ SY+E+ + VH Sbjct 2295 DSISLIMEHMEAGDLLSYLRAARPSSQEALSKLQLPELLSMCLDVANGCSYMEDMHFVHR 2354 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIP--WLAPECLPGG 787 ++ RN L++ G A G +K+ D G+ R+E +P W+A E L G Sbjct 2355 DLACRNCLVSD-GAAIGGRRIVKIGDFGLARDIYKSDYYRKEGEGLLPVRWMALESLVDG 2413 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLT 845 ST D W FG EI G+ P +R+ E + RL +P CP+ L L Sbjct 2414 L--FSTQSDVWAFGVLCWEIFTLGQQPYAARNNFEVLAHVKEGGRLQQPERCPEKLYALL 2471 Query 846 SQCLTYEPTQRPSFRTILRDLTRL 869 QC EP +RPSF+ L L L Sbjct 2472 LQCWRSEPWERPSFKRCLSTLQAL 2495 >sp|Q9WTL4|INSRR_MOUSE Insulin receptor-related protein OS=Mus musculus OX=10090 GN=Insrr PE=1 SV=2 Length=1300 Score = 135 bits (341), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 94/283 (33%), Positives = 147/283 (52%), Gaps = 37/283 (13%) Query 900 IRDLGEGHFGKVSLYCYDPTNDG--TGEM---VAVKALKADCGPQHRSGWKQEIDILRTL 954 IR+LG+G FG V Y+ G GE VA+K + + R + +E +++ Sbjct 982 IRELGQGSFGMV----YEGLARGLEAGEESTPVALKTVNELASARERVEFLKEASVMKAF 1037 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQ-----LLLF 1003 H+++ G QG+ +L ++ME + G L+ +L ++ GL Q ++ Sbjct 1038 KCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSHLRSLRPEAENNPGLPQPALSDMIQM 1095 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 A +I +GMAYL A+ ++HRDLAARN ++ D VKIGDFG+ + V E +YYR G Sbjct 1096 AGEIADGMAYLAAKKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYE-TDYYRKGGKGLL 1154 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 PV W APE LK+ F SDVWSFGV L+E++T + G++ Q+ Sbjct 1155 PVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQ---------GLSNEQV---- 1201 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + + G L + CP ++ LM+ CW+ RPTF +++ Sbjct 1202 -LKFVMDGGVLEELENCPIQLQELMRLCWQHSPRLRPTFVHIL 1243 Score = 73.6 bits (179), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 76/298 (26%), Positives = 121/298 (41%), Gaps = 46/298 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLR-VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 V +++I + LGQG+ VYEG R +E + + + L R+R Sbjct 974 VPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASARER--------- 1024 Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 + F + AS+M H+ + GV +G +++ E + G L LR Sbjct 1025 ----------VEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSL 1074 Query 703 RGHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 R P M+ +A ++A ++YL K VH ++ RN ++++ Sbjct 1075 RPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQ-------DF 1127 Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+ D G+ + + + + W+APE L G +T D W FG L EI Sbjct 1128 TVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGI--FTTHSDVWSFGVVLWEI 1185 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSFRTIL 863 E P Q S + F L E +CP QL L C + P RP+F IL Sbjct 1186 VTLAEQPYQGLSNEQVLKFVMDGGVLEELENCPIQLQELMRLCWQHSPRLRPTFVHIL 1243 >sp|P70451|FER_MOUSE Tyrosine-protein kinase Fer OS=Mus musculus OX=10090 GN=Fer PE=1 SV=2 Length=823 Score = 135 bits (339), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 90/267 (34%), Positives = 136/267 (51%), Gaps = 29/267 (11%) Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG+G+FG+V Y T D T VA+K K D + + + QE IL+ H +I+K Sbjct 570 LGKGNFGEV----YKGTLKDKTP--VAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVK 623 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHY 1019 G C + + + ++ME VP G +L + + L QL+ F+ + GM YL +++ Sbjct 624 LIGVCTQR--QPVYIIMELVPGGDFLTFLRKRKDELKLKQLVRFSLDVAAGMLYLESKNC 681 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRDLAARN L+ + +KI DFG+++ G Y P+ W APE L ++ Sbjct 682 IHRDLAARNCLVGENNTLKISDFGMSRQEDGG--VYSSSGLKQIPIKWTAPEALNYGRYS 739 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA-QGQMTVLRLTELLERGERLPRPD 1138 SDVWSFG+ L+E + +G+ MT + E +ERG R+ P Sbjct 740 SESDVWSFGILLWETFS---------------LGVCPYPGMTNQQAREQVERGYRMSAPQ 784 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENL 1165 CP EV+ +M CW+ + RP F +L Sbjct 785 NCPEEVFTIMMKCWDYKPENRPKFNDL 811 Score = 90.5 bits (223), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 104/453 (23%), Positives = 191/453 (42%), Gaps = 86/453 (19%) Query 430 SSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAK-LRPEDGLYLIHWSTSHPYRLILTVA 488 SS +C ++ ++ D HG + P ++A+ L + G +L+ S P +L+V Sbjct 441 SSTQVCDVISVGERPLAEHDWYHGAI--PRIEAQELLKQQGDFLVRESHGKPGEYVLSVY 498 Query 489 QRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLR 548 DG + R F I+ D + EG G F ++ +L D F+ + Sbjct 499 -----SDGQR----RHFIIQFVDNLYRFEGTG--FSNIPQLI-----------DHHFNTK 536 Query 549 RCCLPQPGETSNLIIMRGARASPR-TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 + + G ++++ + LN +S + LG+G VY+G Sbjct 537 QVITKKSG----VVLLNPIPKDKKWVLNHEDVSLGEL----------LGKGNFGEVYKGT 582 Query 608 LRVEGSGDPEEGKMDDEDPLVPG---RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664 L+ D+ P+ D QEL++ F + A ++ Q Sbjct 583 LK-------------DKTPVAIKTCKEDLPQELKI--------------KFLQEAKILKQ 615 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 H ++ + GVC + ++ E V G +LR+ + + + + + +A+ + Y Sbjct 616 YDHPNIVKLIGVCTQRQPVYIIMELVPGGDFLTFLRKRKDELKLKQLVRFSLDVAAGMLY 675 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---GALSREERVERIP--WL 779 LE+KN +H ++ RN L+ G + +K+SD G+ G + +++IP W Sbjct 676 LESKNCIHRDLAARNCLV-------GENNTLKISDFGMSRQEDGGVYSSSGLKQIPIKWT 728 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838 APE L G S+ D W FG L E G P + + +R +R+ P +C Sbjct 729 APEALNYG--RYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQNC 786 Query 839 P-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P ++ T+ +C Y+P RP F + ++LT ++ Sbjct 787 PEEVFTIMMKCWDYKPENRPKFNDLHKELTVIK 819 >sp|P09208|INSR_DROME Insulin-like receptor OS=Drosophila melanogaster OX=7227 GN=InR PE=1 SV=3 Length=2144 Score = 136 bits (342), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 95/294 (32%), Positives = 152/294 (52%), Gaps = 45/294 (15%) Query 903 LGEGHFGKVS---LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG V L + P +G A+K + + + R+ + E +++ H+ Sbjct 1377 LGQGSFGMVYEGILKSFPP--NGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHV 1434 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------------IGLA------- 998 ++ G C +G+ +L +VME + G L+ YL H IG+ Sbjct 1435 VRLLGVCS-RGQPAL-VVMELMKKGDLKSYLRAHRPEERDEAMMTYLNRIGVTGNVQPPT 1492 Query 999 --QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 ++ A +I +GMAYL A+ ++HRDLAARN ++ +D VKIGDFG+ + + E +YYR Sbjct 1493 YGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYET-DYYR 1551 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 G PV W PE L++ + ASDV+SFGV L+E+ T + P + G++ Sbjct 1552 KGTKGLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLA----AQPYQ-----GLSN 1602 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 Q VLR + G + RP+ CP ++ LM+ CW +S RP+F ++I L+ Sbjct 1603 EQ--VLR---YVIDGGVMERPENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLE 1651 Score = 66.2 bits (160), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 79/310 (25%), Positives = 128/310 (41%), Gaps = 58/310 (19%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V ++ I QL+ LGQG+ VYEG L+ S P G DR +K Sbjct 1366 VLRENIIQLAPLGQGSFGMVYEGILK---SFPPN------------GVDR----ECAIKT 1406 Query 644 LDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 ++ + D F AS+M + H+ + GVC RG ++V E ++ G L +LR Sbjct 1407 VNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSYLRAH 1466 Query 703 R------------------GHV-PMAWKMV--VAQQLASALSYLENKNLVHGNVCGRNIL 741 R G+V P + + +A ++A ++YL K VH ++ RN + Sbjct 1467 RPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCM 1526 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAM 795 +A +K+ D G+ + + + + W+ PE L G S+A Sbjct 1527 VA-------DDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGV--YSSAS 1577 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEP 853 D + FG L E+ P Q S + + + P +CP L L +C + Sbjct 1578 DVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCWHHRS 1637 Query 854 TQRPSFRTIL 863 + RPSF I+ Sbjct 1638 SARPSFLDII 1647 >sp|G5EGK5|CAM1_CAEEL Tyrosine-protein kinase receptor cam-1 OS=Caenorhabditis elegans OX=6239 GN=cam-1 PE=1 SV=1 Length=928 Score = 135 bits (339), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 96/281 (34%), Positives = 134/281 (48%), Gaps = 29/281 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG FG V Y M VAVK + D R+ +QEI + T H ++IK Sbjct 596 IGEGQFGVVHSGIYTSGLFAPEPMAVAVKKCRHDATNAERAQLEQEIRAVATFDHPNVIK 655 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIG-----LAQLLLFAQQICEG 1010 G C + SL V EY+ G L + L H +G A+ L A QI G Sbjct 656 LIGVC--YMDNSLLAVFEYMVHGDLHELLKVRVPPADHDMGGITEANAEFLYIATQIALG 713 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 M YL + ++HRDLA RN L+ + R +KI DFGL + G +YY++ PV W + Sbjct 714 MEYLASMSFVHRDLATRNCLVGDTRTIKIADFGLMR-TSYGSDYYKMLHRSWMPVRWMSK 772 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E +++ +F ASDVWSFGVTL+E+ + + P G + Q + EL+ Sbjct 773 EAIEQGRFSEASDVWSFGVTLWEIWSF---GRQP------YEGASNQQ-----VIELVAN 818 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 L P CP +Y LM CW RPTF + L++ Sbjct 819 RHLLECPHNCPTNIYSLMVECWHENIERRPTFSEIRSRLQS 859 Score = 60.5 bits (145), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 61/231 (26%), Positives = 103/231 (45%), Gaps = 29/231 (13%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-------RERGHVPMAWK--M 712 ++ H ++ + GVC + V EY+ HG L L+ + G + A + Sbjct 645 VATFDHPNVIKLIGVCYMDNSLLAVFEYMVHGDLHELLKVRVPPADHDMGGITEANAEFL 704 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 +A Q+A + YL + + VH ++ RN L+ G + IK++D G+ + + Sbjct 705 YIATQIALGMEYLASMSFVHRDLATRNCLV-------GDTRTIKIADFGLMRTSYGSDYY 757 Query 771 ERVER----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + + R + W++ E + G S A D W FG TL EI G P + S + Sbjct 758 KMLHRSWMPVRWMSKEAIEQG--RFSEASDVWSFGVTLWEIWSFGRQPYEGASNQQVIEL 815 Query 827 YQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 +H L P +CP + +L +C +RP+F I +RLQ +LA Sbjct 816 VANRHLLECPHNCPTNIYSLMVECWHENIERRPTFSEI---RSRLQSWSLA 863 >sp|P14616|INSRR_HUMAN Insulin receptor-related protein OS=Homo sapiens OX=9606 GN=INSRR PE=1 SV=2 Length=1297 Score = 135 bits (340), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 102/321 (32%), Positives = 161/321 (50%), Gaps = 50/321 (16%) Query 879 TVNPDS-PASDPTV-----FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG--TGEM---V 927 +VNP+ ASD V + + IR+LG+G FG V Y+ G GE V Sbjct 955 SVNPEYFSASDMYVPDEWEVPREQISIIRELGQGSFGMV----YEGLARGLEAGEESTPV 1010 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K + P+ + +E +++ H+++ G QG+ +L ++ME + G L+ Sbjct 1011 ALKTVNELASPRECIEFLKEASVMKAFKCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLK 1068 Query 988 DYL-------------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034 +L P+ ++G +++ A +I +GMAYL A ++HRDLAARN ++ D Sbjct 1069 SHLRSLRPEAENNPGLPQPALG--EMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQD 1126 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 VKIGDFG+ + V E +YYR G PV W APE LK+ F SDVWSFGV L+E+ Sbjct 1127 FTVKIGDFGMTRDVYE-TDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEI 1185 Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154 +T + G++ Q+ + + G L + CP ++ LM CW+ Sbjct 1186 VTLAEQPYQ---------GLSNEQV-----LKFVMDGGVLEELEGCPLQLQELMSRCWQP 1231 Query 1155 EASFRPTFENLIPILKTVHEK 1175 RP+F + IL ++ E+ Sbjct 1232 NPRLRPSFTH---ILDSIQEE 1249 Score = 75.9 bits (185), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 78/300 (26%), Positives = 126/300 (42%), Gaps = 44/300 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +++I+ + LGQG+ VYEG R +G+ + P+ L+ V ++ Sbjct 974 VPREQISIIRELGQGSFGMVYEGLARGLEAGE-------ESTPVA--------LKTVNEL 1018 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 P + F + AS+M H+ + GV +G +++ E + G L LR R Sbjct 1019 ASPRE---CIEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLR 1075 Query 704 GHV--------PMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 P +M+ +A ++A ++YL VH ++ RN ++++ Sbjct 1076 PEAENNPGLPQPALGEMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQ-------DFT 1128 Query 755 IKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 +K+ D G+ + + + + W+APE L G +T D W FG L EI Sbjct 1129 VKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGI--FTTHSDVWSFGVVLWEIV 1186 Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSFRTILRDL 866 E P Q S + F L E CP QL L S+C P RPSF IL + Sbjct 1187 TLAEQPYQGLSNEQVLKFVMDGGVLEELEGCPLQLQELMSRCWQPNPRLRPSFTHILDSI 1246 >sp|Q05876|FYN_CHICK Tyrosine-protein kinase Fyn OS=Gallus gallus OX=9031 GN=FYN PE=1 SV=2 Length=534 Score = 132 bits (331), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 88/273 (32%), Positives = 136/273 (50%), Gaps = 29/273 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 + LG+G F +V + T +G + VA+K LK G + +E I++ L H+ ++ Sbjct 272 QKLGQGCFAEV----WRGTWNGNTK-VAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLV 324 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQ 1017 + + + +V EY+ GSL +L ++ L L+ A Q+ GMAY+ Sbjct 325 QLYAVVS---RRPIYIVTEYMSKGSLLIFLKDGEGRALKLPNLVDMAAQVAAGMAYIERM 381 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +YIHRDL + N+L+ N + KI DFGLA+ + + Y R+ P+ W APE + Sbjct 382 NYIHRDLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGR 439 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFG+ L EL+T + M + E +ERG R+P P Sbjct 440 FTIKSDVWSFGILLTELVTKGR--------------VPYPGMNNREVLEQVERGYRMPCP 485 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 CP ++ LM +CW+ + RPTFE L L+ Sbjct 486 QDCPISLHELMIHCWKKDPEERPTFEYLQGFLE 518 Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 66/230 (29%), Positives = 104/230 (45%), Gaps = 19/230 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P +F E A +M ++ H L ++ V R P I VTEY+ G L + Sbjct 292 KVAIKTLKPGTMSPE-SFLEEAQIMKKLKHDKLVQLYAVVSRRPIYI-VTEYMSKGSLLI 349 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G +V +A Q+A+ ++Y+E N +H ++ NIL+ G K Sbjct 350 FLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILV-------GNGLICK 402 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 403 IADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKS--DVWSFGILLTELVTKG 460 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 P + E +R +R+P P CP L L C +P +RP+F Sbjct 461 RVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTF 510 >sp|Q10925|SID3_CAEEL Tyrosine-protein kinase sid-3 OS=Caenorhabditis elegans OX=6239 GN=sid-3 PE=1 SV=2 Length=1237 Score = 134 bits (338), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 90/264 (34%), Positives = 133/264 (50%), Gaps = 24/264 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG F V + +N GT VAVK L+ D P + E L L H +I+ Sbjct 113 IGEGSFAVVKRGTWTQSN-GTHVNVAVKILR-DISPNIMDDLRVEASHLLKLQHPSLIRL 170 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 G + +V E GSL D L + + +++L + QI + + +L ++H Sbjct 171 YGIVR----QPAMMVFELCEGGSLLDRLRDDKKAILLVSRLHDYCMQIAKALQFLESKHC 226 Query 1020 IHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRD+AARN+LL D R VKI DFGL +A+ E + Y + P W PE L+ KF Sbjct 227 VHRDVAARNILLARDERTVKICDFGLMRALKENEQMYTMAPQKKVPFAWCPPEALRHRKF 286 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 +ASDVWS+GVT++E+ T F E + + VL+ ++ GERL +P Sbjct 287 SHASDVWSYGVTIWEVFT-----------FGEEPWVGCRAIDVLK---NIDAGERLEKPK 332 Query 1139 KCPCEVYHLMKNCWETEASFRPTF 1162 C +Y +MKNCW+ + R F Sbjct 333 YCSERIYQIMKNCWKFNPAERCKF 356 Score = 67.0 bits (162), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 72/247 (29%), Positives = 114/247 (46%), Gaps = 22/247 (9%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 + G + V +K+L +I AS + ++ H L ++G+ VR P +MV E Sbjct 128 QSNGTHVNVAVKILRDISPNIMDDLRVEASHLLKLQHPSLIRLYGI-VRQPA-MMVFELC 185 Query 691 EHGPLDVWLRRERGHVPMAWKM-VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 E G L LR ++ + + ++ Q+A AL +LE+K+ VH +V RNILLAR E Sbjct 186 EGGSLLDRLRDDKKAILLVSRLHDYCMQIAKALQFLESKHCVHRDVAARNILLAR---DE 242 Query 750 GTSPFIKLSDPGVGLGALSREERV------ERIP--WLAPECLPGGANSLSTAMDKWGFG 801 T +K+ D G+ + AL E++ +++P W PE L S A D W +G Sbjct 243 RT---VKICDFGL-MRALKENEQMYTMAPQKKVPFAWCPPEAL--RHRKFSHASDVWSYG 296 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSF 859 T+ E+ GE P + RL +P C + + + C + P +R F Sbjct 297 VTIWEVFTFGEEPWVGCRAIDVLKNIDAGERLEKPKYCSERIYQIMKNCWKFNPAERCKF 356 Query 860 RTILRDL 866 I DL Sbjct 357 GAIREDL 363 >sp|P42681|TXK_HUMAN Tyrosine-protein kinase TXK OS=Homo sapiens OX=9606 GN=TXK PE=1 SV=3 Length=527 Score = 131 bits (329), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 91/289 (31%), Positives = 137/289 (47%), Gaps = 47/289 (16%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGE-----MVAVKALKADCGPQHRSGWKQEIDILRTL 954 I+++G G FG V L GE VA+KA+ G + +E ++ L Sbjct 274 IKEIGSGQFGVVHL----------GEWRSHIQVAIKAINE--GSMSEEDFIEEAKVMMKL 321 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMA 1012 H +++ G C + K L +V E++ G L +YL + L + +L + Q ICEGM Sbjct 322 SHSKLVQLYGVCIQR--KPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGME 379 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 YL YIHRDLAARN L+ + +VKI DFG+ + V + Y P+ W PE Sbjct 380 YLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDE--YVSSFGAKFPIKWSPPEV 437 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM-----TVLRLTEL 1127 K+ SDVWSFGV ++E+ T +G+M + L++ E Sbjct 438 FLFNKYSSKSDVWSFGVLMWEVFT-------------------EGKMPFENKSNLQVVEA 478 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 + G RL RP P +Y +M +CW + RPTF L+ + + E + Sbjct 479 ISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEIAETW 527 Score = 89.0 bits (219), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 60/223 (27%), Positives = 106/223 (48%), Gaps = 18/223 (8%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F E A +M ++SH+ L ++GVC++ +VTE++E+G L +LR +G + + V Sbjct 311 FIEEAKVMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSV 370 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 Q + + YLE +H ++ RN L++ ++ +K+SD G+ L +E V Sbjct 371 CQDICEGMEYLERNGYIHRDLAARNCLVS-------STCIVKISDFGMTRYVLD-DEYVS 422 Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 I W PE N S+ D W FG + E+ +G+ P +++S + Sbjct 423 SFGAKFPIKWSPPEVFL--FNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAIS 480 Query 829 RQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTILRDLTRL 869 RL P ++ + C +P RP+F +LR +T + Sbjct 481 EGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEI 523 >sp|P00530|FPS_FUJSV Tyrosine-protein kinase transforming protein Fps OS=Fujinami sarcoma virus OX=11885 GN=V-FPS PE=3 SV=1 Length=873 Score = 134 bits (336), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 90/276 (33%), Positives = 140/276 (51%), Gaps = 31/276 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G+FG+V + D T VAVK+ + P+ ++ + QE IL+ H +I++ Sbjct 618 IGRGNFGEV--FSGRLRADNTP--VAVKSCRETLPPELKAKFLQEARILKQCNHPNIVRL 673 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 G C + + + +VME V G +L PR + + +L+ + GM YL ++H Sbjct 674 IGVCTQK--QPIYIVMELVQGGDFLSFLRSKGPR--LKMKKLIKMMENAAAGMEYLESKH 729 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRDLAARN L+ +KI DFG+++ +G Y PV W APE L + Sbjct 730 CIHRDLAARNCLVTEKNTLKISDFGMSRQEEDG-VYASTGGMKQIPVKWTAPEALNYGWY 788 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SDVWSFG+ L+E + L + ++ + E +E+G RL P+ Sbjct 789 SSESDVWSFGILLWEAFS--------------LGAVPYANLSNQQTREAIEQGVRLEPPE 834 Query 1139 KCPCEVYHLMKNCWETEASFRPTF----ENLIPILK 1170 +CP +VY LM+ CWE + RP+F ++LI I K Sbjct 835 QCPEDVYRLMQRCWEYDPHRRPSFGAVHQDLIAIRK 870 Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 72/280 (26%), Positives = 124/280 (44%), Gaps = 40/280 (14%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 +G+G V+ GRLR D P+ ++ + L P ++ Sbjct 618 IGRGNFGEVFSGRLRA------------DNTPVA--------VKSCRETLPP---ELKAK 654 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F + A ++ Q +H ++ + GVC + +V E V+ G +LR + + M + + Sbjct 655 FLQEARILKQCNHPNIVRLIGVCTQKQPIYIVMELVQGGDFLSFLRSKGPRLKMKKLIKM 714 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSRE 770 + A+ + YLE+K+ +H ++ RN L+ +K+SD G+ G + Sbjct 715 MENAAAGMEYLESKHCIHRDLAARNCLVTEKNT-------LKISDFGMSRQEEDGVYAST 767 Query 771 ERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 +++IP W APE L G S+ D W FG L E G P + S + + Sbjct 768 GGMKQIPVKWTAPEALNYGW--YSSESDVWSFGILLWEAFSLGAVPYANLSNQQTREAIE 825 Query 829 RQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866 + RL P CP+ + L +C Y+P +RPSF + +DL Sbjct 826 QGVRLEPPEQCPEDVYRLMQRCWEYDPHRRPSFGAVHQDL 865 >sp|Q6P6U0|FGR_RAT Tyrosine-protein kinase Fgr OS=Rattus norvegicus OX=10116 GN=Fgr PE=1 SV=1 Length=517 Score = 130 bits (328), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 91/288 (32%), Positives = 137/288 (48%), Gaps = 29/288 (10%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 A D + + R LG G FG V L ++ + VAVK LK G + Sbjct 240 AKDAWEIDRNSIALDRRLGTGCFGDVWLGTWNCSTK-----VAVKTLKP--GTMSPKAFL 292 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLL 1002 +E I++ L H+ +++ E+ + +V E++ GSL D+L H++ L L+ Sbjct 293 EEAQIMKLLRHDKLVQLYAVV---SEEPIYIVTEFMCYGSLLDFLKDRKGHNLMLPNLVD 349 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 A Q+ EGMAY+ +YIHRDL A N+L+ + KI DFGLA+ + + Y ++ Sbjct 350 MAAQVAEGMAYMERMNYIHRDLRAANILVGEHLICKIADFGLARLIVDDE--YNPQQGTK 407 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 P+ W APE +F SDVWSFG+ L EL+T + M Sbjct 408 FPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGR--------------VPYPGMNNR 453 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + E +E G +P P CP +Y +M+ W + RPTFE L L+ Sbjct 454 EVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLE 501 Score = 75.1 bits (183), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 64/233 (27%), Positives = 105/233 (45%), Gaps = 19/233 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P AF E A +M + H L ++ V P I VTE++ +G L Sbjct 275 KVAVKTLKPGTMS-PKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYI-VTEFMCYGSLLD 332 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ +GH M +V +A Q+A ++Y+E N +H ++ NIL+ G K Sbjct 333 FLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILV-------GEHLICK 385 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ + E ++ I W APE G ++ + D W FG L E+ G Sbjct 386 IADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKS--DVWSFGILLTELITKG 443 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTI 862 P + E + + +P P CP L + Q +P +RP+F + Sbjct 444 RVPYPGMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYL 496 >sp|P00542|FES_FSVGA Tyrosine-protein kinase transforming protein Fes OS=Feline sarcoma virus (strain Gardner-Arnstein) OX=11774 GN=V-FES PE=3 SV=1 Length=609 Score = 132 bits (331), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 93/310 (30%), Positives = 149/310 (48%), Gaps = 24/310 (8%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 QP + +N P D V + L +G G+FG+V + D T +VAV Sbjct 322 QPLTKKSGIVLNRAVP-KDKWVLNHEDLVLGEQIGRGNFGEV--FSGRLRADNT--LVAV 376 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K+ + P ++ + QE IL+ H +I++ G C + + + +VME V G + Sbjct 377 KSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVCTQK--QPIYIVMELVQGGDFLTF 434 Query 990 LPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 L + + LL GM YL ++ IHRDLAARN L+ ++KI DFG+++ Sbjct 435 LRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSRE 494 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 +G Y PV W APE L ++ SDVWSFG+ L+E + +S P Sbjct 495 AADGI-YAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFS-LGASPYP--- 549 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 ++ + E +E+G RLP P+ CP V+ LM+ CW E RP+F + Sbjct 550 ----------NLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQ 599 Query 1168 ILKTVHEKYQ 1177 L+++ ++++ Sbjct 600 ELQSIRKRHR 609 Score = 100 bits (249), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 82/285 (29%), Positives = 127/285 (45%), Gaps = 40/285 (14%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 +G+G V+ GRLR + + LV ++ + L P DI Sbjct 353 QIGRGNFGEVFSGRLRADNT-------------LVA-------VKSCRETLPP---DIKA 389 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F + A ++ Q SH ++ + GVC + +V E V+ G +LR E + M + Sbjct 390 KFLQEAKILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQ 449 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGAL 767 + A+ + YLE+K +H ++ RN L+ + +K+SD G+ G+ A Sbjct 450 MVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNV-------LKISDFGMSREAADGIYAA 502 Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 S R + W APE L G S+ D W FG L E G +P + S + F Sbjct 503 SGGLRQVPVKWTAPEALNYG--RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFV 560 Query 828 QRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 ++ RLP P CP + L QC YEP QRPSF I ++L ++ Sbjct 561 EKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQELQSIR 605 >sp|Q968Y9|INSR_CAEEL Insulin-like receptor OS=Caenorhabditis elegans OX=6239 GN=daf-2 PE=1 SV=2 Length=1846 Score = 134 bits (337), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 99/292 (34%), Positives = 137/292 (47%), Gaps = 50/292 (17%) Query 904 GEGHFGKVSLYCYDPTNDGTGEMV-----------AVKALKADCGPQHRSGWKQEIDILR 952 GEG FGKV L GTG V A+K D + E +I++ Sbjct 1253 GEGSFGKVYL--------GTGNNVVSLMGDRFGPCAIKINVDDPASTENLNYLMEANIMK 1304 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------------IGL 997 I+K G + +VME + LG+LRDYL I Sbjct 1305 NFKTNFIVKLYGVISTV--QPAMVVMEMMDLGNLRDYLRSKREDEVFNETDCNFFDIIPR 1362 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + +A QIC+GMAYL + + HRDLAARN +++ D VKIGDFG+A+ + H+YY+ Sbjct 1363 DKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFY-HDYYKP 1421 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 PV W +PE LK+ KF SDVWSFGV LYE++T P IG++ Sbjct 1422 SGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTL---GAQP------YIGLSND 1472 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + VL + + + +P+ C Y +MK CW RPTF L+ +L Sbjct 1473 E--VLNYIGMARK--VIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLVHLL 1520 Score = 57.4 bits (137), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 54/250 (22%), Positives = 98/250 (39%), Gaps = 32/250 (13%) Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 DR + + V DP+ + L + A++M + ++GV ++V E ++ Sbjct 1274 DRFGPCAIKINVDDPASTE-NLNYLMEANIMKNFKTNFIVKLYGVISTVQPAMVVMEMMD 1332 Query 692 HGPLDVWLRRERGH-------------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGR 738 G L +LR +R +P A Q+ ++YLE+ H ++ R Sbjct 1333 LGNLRDYLRSKREDEVFNETDCNFFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAAR 1392 Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLS 792 N ++ R +K+ D G+ + +R+ + W++PE L G Sbjct 1393 NCMINR-------DETVKIGDFGMARDLFYHDYYKPSGKRMMPVRWMSPESLKDG--KFD 1443 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-LPEPSCPQ--LATLTSQCL 849 + D W FG L E+ G P S E ++ + + +P C + + C Sbjct 1444 SKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCW 1503 Query 850 TYEPTQRPSF 859 Y P RP+F Sbjct 1504 RYSPRDRPTF 1513 >sp|P35991|BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus musculus OX=10090 GN=Btk PE=1 SV=4 Length=659 Score = 132 bits (331), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 87/279 (31%), Positives = 139/279 (50%), Gaps = 28/279 (10%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +++LG G FG V + D VA+K ++ G + +E ++ L HE + Sbjct 405 LKELGTGQFGVVKYGKWRGQYD-----VAIKMIRE--GSMSEDEFIEEAKVMMNLSHEKL 457 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ 1017 ++ G C Q + + ++ EY+ G L +YL RH QLL + +CE M YL ++ Sbjct 458 VQLYGVCTKQ--RPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESK 515 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 ++HRDLAARN L+++ +VK+ DFGL++ V + Y PV W PE L K Sbjct 516 QFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDE--YTSSVGSKFPVRWSPPEVLMYSK 573 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SD+W+FGV ++E+ + L + + T E + +G RL RP Sbjct 574 FSSKSDIWAFGVLMWEIYS--------------LGKMPYERFTNSETAEHIAQGLRLYRP 619 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP-ILKTVHEK 1175 VY +M +CW +A RP+F+ L+ IL + E+ Sbjct 620 HLASERVYTIMYSCWHEKADERPSFKILLSNILDVMDEE 658 Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 82/317 (26%), Positives = 136/317 (43%), Gaps = 55/317 (17%) Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP-----E 617 + + + +P T L S+ +D K++T L LG G V G+ R G D Sbjct 377 VSKQNKNAPSTAGLGYGSWE-IDPKDLTFLKELGTGQFGVVKYGKWR--GQYDVAIKMIR 433 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 EG M +++ F E A +M +SH L ++GVC Sbjct 434 EGSMSEDE-----------------------------FIEEAKVMMNLSHEKLVQLYGVC 464 Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737 + ++TEY+ +G L +LR R + + + + A+ YLE+K +H ++ Sbjct 465 TKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAA 524 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV---ERIP--WLAPECLPGGANSLS 792 RN L+ G+ +K+SD G+ L E + P W PE L + S Sbjct 525 RNCLVNDQGV-------VKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVL--MYSKFS 575 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQ--RQHRLPEPSCPQLATLTSQCL 849 + D W FG + EI G+ P + + SE EH Q R +R P + ++ T+ C Sbjct 576 SKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYR-PHLASERVYTIMYSCW 634 Query 850 TYEPTQRPSFRTILRDL 866 + +RPSF+ +L ++ Sbjct 635 HEKADERPSFKILLSNI 651 >sp|Q98949|TYRO3_CHICK Tyrosine-protein kinase receptor TYRO3 OS=Gallus gallus OX=9031 GN=TYRO3 PE=1 SV=1 Length=873 Score = 133 bits (334), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 96/274 (35%), Positives = 134/274 (49%), Gaps = 28/274 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHI 959 R LG+G FG V +DG+ + VAVK LKAD + +E ++ H H+ Sbjct 509 RMLGKGEFGSVREALLK-LDDGSFQKVAVKMLKADIFTSTDIEEFLREAACMKEFDHPHV 567 Query 960 IKYKGCC-EDQGEKSLQLVMEYVPL---GSLRDYLPRHSIG-------LAQLLLFAQQIC 1008 K G + + L + M +P G L +L IG L LL F I Sbjct 568 TKLIGVSLRSRPKGRLPIPMVILPFMKHGDLHAFLLMSRIGENPFNLPLQTLLKFMIDIA 627 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 GM YL ++++IHRDLAARN +LD + V + DFGL+K + G +YYR PV W Sbjct 628 SGMEYLSSKNFIHRDLAARNCMLDENMNVSVADFGLSKKIYSG-DYYRQGCASKLPVKWL 686 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A E L + + SDVW+FGVT++E++T Q+P GI + + L Sbjct 687 ALESLADNLYTTHSDVWAFGVTMWEIVTR---GQTP------YAGIENAE-----IYNYL 732 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 G RL +P +C +VY LM CW E RP+F Sbjct 733 ISGNRLKQPPECLEDVYDLMCRCWHPEPKLRPSF 766 Score = 73.6 bits (179), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 78/291 (27%), Positives = 129/291 (44%), Gaps = 41/291 (14%) Query 632 DRGQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PE 682 D G +V +K+L + DI F A+ M + H H+ + GV +R P Sbjct 527 DDGSFQKVAVKMLKADIFTSTDIE-EFLREAACMKEFDHPHVTKLIGVSLRSRPKGRLPI 585 Query 683 NIMVTEYVEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737 +++ +++HG L +L R ++P+ + +AS + YL +KN +H ++ Sbjct 586 PMVILPFMKHGDLHAFLLMSRIGENPFNLPLQTLLKFMIDIASGMEYLSSKNFIHRDLAA 645 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIP--WLAPECLPGGANSL 791 RN +L + + ++D G+ G R+ ++P WLA E L N Sbjct 646 RNCMLDE-------NMNVSVADFGLSKKIYSGDYYRQGCASKLPVKWLALESL--ADNLY 696 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCPQ-LATLTSQCL 849 +T D W FG T+ EI G+ P +E ++ +RL + P C + + L +C Sbjct 697 TTHSDVWAFGVTMWEIVTRGQTPYAGIENAEIYNYLISGNRLKQPPECLEDVYDLMCRCW 756 Query 850 TYEPTQRPSFRTILRDLT----RLQPHNLA-DVLTVN----PDSPASDPTV 891 EP RPSF + L R+ +L+ D L VN +S SDP V Sbjct 757 HPEPKLRPSFGVLRSQLEMIRGRMSTLSLSQDPLYVNIGKDKESSVSDPAV 807 >sp|Q9Z139|ROR1_MOUSE Inactive tyrosine-protein kinase transmembrane receptor ROR1 OS=Mus musculus OX=10090 GN=Ror1 PE=2 SV=2 Length=937 Score = 133 bits (334), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 86/288 (30%), Positives = 141/288 (49%), Gaps = 37/288 (13%) Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 ++ + +LGE FGK+ + Y P D ++VA+K LK PQ + ++QE ++ L+ Sbjct 473 VRFMEELGECTFGKIYKGHLYLPGMD-HAQLVAIKTLKDYNNPQQWTEFQQEASLMAELH 531 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ------------ 999 H +I+ G E+ + ++ EY+ G L ++L P +G + Sbjct 532 HPNIVCLLGAVTQ--EQPVCMLFEYMNQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDH 589 Query 1000 --LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 L A QI GM YL + ++H+DLAARN+L+ VKI D GL++ + +YYRV Sbjct 590 GDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSA-DYYRV 648 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 + P+ W PE + KF SD+WSFGV L+E+ + G + Sbjct 649 QSKSSLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSF---------GLQPYYGFSNQ 699 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + E++ + + LP + CP +Y LM CW S RP F+++ Sbjct 700 E-----VIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDI 742 Score = 73.2 bits (178), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 73/295 (25%), Positives = 122/295 (41%), Gaps = 52/295 (18%) Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651 + LG+ T +Y+G L +PG D Q L + + D ++ Sbjct 476 MEELGECTFGKIYKGHL------------------YLPGMDHAQ-LVAIKTLKDYNNPQQ 516 Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711 F + ASLM+++ H ++ + G + M+ EY+ G L +L H + Sbjct 517 WTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYMNQGDLHEFLIMRSPHSDVGCS 576 Query 712 ----------------MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 + +A Q+A+ + YL + VH ++ RNIL+ G + Sbjct 577 SDEDGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILI-------GEQLHV 629 Query 756 KLSDPGVGLGALSRE-ERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 K+SD G+ S + RV+ I W+ PE + G S+ D W FG L EI Sbjct 630 KISDLGLSREIYSADYYRVQSKSSLPIRWMPPEAIMYG--KFSSDSDIWSFGVVLWEIFS 687 Query 810 DGEAPLQSRSPSEKEHFYQRQHRLP--EPSCPQLATLTSQCLTYEPTQRPSFRTI 862 G P S E +++ LP E P++ +L ++C P++RP F+ I Sbjct 688 FGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDI 742 >sp|Q01973|ROR1_HUMAN Inactive tyrosine-protein kinase transmembrane receptor ROR1 OS=Homo sapiens OX=9606 GN=ROR1 PE=1 SV=2 Length=937 Score = 133 bits (334), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 93/331 (28%), Positives = 156/331 (47%), Gaps = 38/331 (11%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV-S 912 Q+ S + R ++ N+ ++ +N P S ++ + +LGE FGK+ Sbjct 431 NQKSSSAPVQRQPKHVRGQNV-EMSMLNAYKPKSKAKELPLSAVRFMEELGECAFGKIYK 489 Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972 + Y P D ++VA+K LK PQ + ++QE ++ L+H +I+ G E+ Sbjct 490 GHLYLPGMDH-AQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQ--EQ 546 Query 973 SLQLVMEYVPLGSLRDYL----PRHSIGLAQ--------------LLLFAQQICEGMAYL 1014 + ++ EY+ G L ++L P +G + L A QI GM YL Sbjct 547 PVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLHIAIQIAAGMEYL 606 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 + ++H+DLAARN+L+ VKI D GL++ + +YYRV+ P+ W PE + Sbjct 607 SSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSA-DYYRVQSKSLLPIRWMPPEAIM 665 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SD+WSFGV L+E+ + G + + + E++ + + L Sbjct 666 YGKFSSDSDIWSFGVVLWEIFSF---------GLQPYYGFSNQE-----VIEMVRKRQLL 711 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P + CP +Y LM CW S RP F+++ Sbjct 712 PCSEDCPPRMYSLMTECWNEIPSRRPRFKDI 742 Score = 74.3 bits (181), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 71/277 (26%), Positives = 119/277 (43%), Gaps = 34/277 (12%) Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTH 669 +E G+ GK+ +PG D Q L + + D ++ F + ASLM+++ H + Sbjct 476 MEELGECAFGKIYKGHLYLPGMDHAQ-LVAIKTLKDYNNPQQWTEFQQEASLMAELHHPN 534 Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK----------------MV 713 + + G + M+ EY+ G L +L H + + Sbjct 535 IVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLH 594 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-ER 772 +A Q+A+ + YL + VH ++ RNIL+ G +K+SD G+ S + R Sbjct 595 IAIQIAAGMEYLSSHFFVHKDLAARNILI-------GEQLHVKISDLGLSREIYSADYYR 647 Query 773 VER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 V+ I W+ PE + G S+ D W FG L EI G P S E Sbjct 648 VQSKSLLPIRWMPPEAIMYG--KFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMV 705 Query 828 QRQHRLP--EPSCPQLATLTSQCLTYEPTQRPSFRTI 862 +++ LP E P++ +L ++C P++RP F+ I Sbjct 706 RKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDI 742 >sp|Q99ML2|TNK1_MOUSE Non-receptor tyrosine-protein kinase TNK1 OS=Mus musculus OX=10090 GN=Tnk1 PE=1 SV=2 Length=666 Score = 131 bits (330), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 94/277 (34%), Positives = 135/277 (49%), Gaps = 28/277 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-----WKQEIDILRTLYHE 957 LG G FG V + G VAVK+L+ GP+ G + +E+ ++ L H Sbjct 122 LGSGCFGVVHRGLWT-LPSGQSIPVAVKSLRV--GPEGPMGTELGDFLREVSVMMKLEHP 178 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLR----DYLPRHSIGLAQLLLFAQQICEGMAY 1013 H+++ G Q LQ+VME PLGSL P + +A L LF +Q+ MAY Sbjct 179 HVLRLHGLVLGQ---PLQMVMELAPLGSLHARLTAPAPTPPLPVALLCLFLRQLAGAMAY 235 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 L + +HRDLA RN+LL + R++K+ DFGL + + Y + P W APE L Sbjct 236 LGSCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESL 295 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 ++ F ASDVW FGVTL+E+ + + + G L L L + R Sbjct 296 RQGAFSSASDVWMFGVTLWEMFSGGEEPWA-------------GVPPYLILQRLEKDRAR 342 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 LP+P C +Y L CW + RP+F NL +L+ Sbjct 343 LPKPPLCSRALYSLALRCWAPHPADRPSFSNLEGLLQ 379 Score = 67.4 bits (163), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 71/221 (32%), Positives = 103/221 (47%), Gaps = 24/221 (11%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV--WLRRERGHVPMAWKM 712 F S+M ++ H H+ +HG+ + P MV E G L +P+A Sbjct 165 FLREVSVMMKLEHPHVLRLHGLVLGQPLQ-MVMELAPLGSLHARLTAPAPTPPLPVALLC 223 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV--GLGALSRE 770 + +QLA A++YL + LVH ++ RN+LLA + IK++D G+ LG +R Sbjct 224 LFLRQLAGAMAYLGSCGLVHRDLATRNLLLA-------SPRMIKVADFGLVRPLGG-ARG 275 Query 771 ERVERIP------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK- 823 V P W APE L GA S+A D W FG TL E+ GE P P Sbjct 276 RYVMGGPRPIPYAWCAPESLRQGA--FSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLIL 333 Query 824 EHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTI 862 + + + RLP+P C + L +L +C P RPSF + Sbjct 334 QRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFSNL 374 >sp|P00543|FES_FSVST Tyrosine-protein kinase transforming protein Fes OS=Feline sarcoma virus (strain Snyder-Theilen) OX=11780 GN=V-FES PE=3 SV=1 Length=477 Score = 129 bits (323), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 91/310 (29%), Positives = 146/310 (47%), Gaps = 24/310 (8%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 QP + +N P D V + L +G G+FG+V + +VAV Sbjct 190 QPLTKKSGIVLNRAVP-KDKWVLNHEDLVLGEQIGRGNFGEV----FSGRLRADNTLVAV 244 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K+ + P ++ + QE IL+ H +I++ G C + + + +VME V G + Sbjct 245 KSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVCTQK--QPIYIVMELVQGGDFLTF 302 Query 990 LPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 L + + LL GM YL ++ IHRDLAARN L+ ++KI DFG+++ Sbjct 303 LRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSRE 362 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 +G Y PV W APE L ++ SDVWSFG+ L+E + +S P Sbjct 363 EADG-VYAASGGLRLVPVKWTAPEALNYGRYSSESDVWSFGILLWETFS-LGASPYP--- 417 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 ++ + E +E+G RLP P+ CP V+ LM+ CW E RP+F Sbjct 418 ----------NLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAFYQ 467 Query 1168 ILKTVHEKYQ 1177 L+++ ++++ Sbjct 468 ELQSIRKRHR 477 Score = 99.4 bits (246), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 81/285 (28%), Positives = 127/285 (45%), Gaps = 40/285 (14%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 +G+G V+ GRLR + + LV ++ + L P DI Sbjct 221 QIGRGNFGEVFSGRLRADNT-------------LVA-------VKSCRETLPP---DIKA 257 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F + A ++ Q SH ++ + GVC + +V E V+ G +LR E + M + Sbjct 258 KFLQEAKILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQ 317 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGAL 767 + A+ + YLE+K +H ++ RN L+ + +K+SD G+ G+ A Sbjct 318 MVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNV-------LKISDFGMSREEADGVYAA 370 Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 S R+ + W APE L G S+ D W FG L E G +P + S + F Sbjct 371 SGGLRLVPVKWTAPEALNYG--RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFV 428 Query 828 QRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 ++ RLP P CP + L QC YEP QRPSF ++L ++ Sbjct 429 EKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAFYQELQSIR 473 >sp|P14234|FGR_MOUSE Tyrosine-protein kinase Fgr OS=Mus musculus OX=10090 GN=Fgr PE=1 SV=2 Length=517 Score = 129 bits (324), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 88/273 (32%), Positives = 132/273 (48%), Gaps = 29/273 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LG G FG V L ++ + VAVK LK G + +E I++ L H+ ++ Sbjct 255 RRLGTGCFGDVWLGTWNCSTK-----VAVKTLKP--GTMSPKAFLEEAQIMKLLRHDKLV 307 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQ 1017 + E+ + +V E++ GSL D+L ++ L L+ A Q+ EGMAY+ Sbjct 308 QLYAVV---SEEPIYIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQVAEGMAYMERM 364 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +YIHRDL A N+L+ + KI DFGLA+ + + Y ++ P+ W APE + Sbjct 365 NYIHRDLRAANILVGEYLICKIADFGLARLIEDNE--YNPQQGTKFPIKWTAPEAALFGR 422 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFG+ L EL+T + M + E +E G +P P Sbjct 423 FTVKSDVWSFGILLTELITKGR--------------VPYPGMNNREVLEQVEHGYHMPCP 468 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 CP +Y +M+ W + RPTFE L L+ Sbjct 469 PGCPASLYEVMEQAWRLDPEERPTFEYLQSFLE 501 Score = 69.3 bits (168), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 63/233 (27%), Positives = 102/233 (44%), Gaps = 19/233 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P AF E A +M + H L ++ V P I VTE++ +G L Sbjct 275 KVAVKTLKPGTMS-PKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYI-VTEFMCYGSLLD 332 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ G M +V +A Q+A ++Y+E N +H ++ NIL+ G K Sbjct 333 FLKDREGQNLMLPHLVDMAAQVAEGMAYMERMNYIHRDLRAANILV-------GEYLICK 385 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E ++ I W APE G ++ + D W FG L E+ G Sbjct 386 IADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKS--DVWSFGILLTELITKG 443 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTI 862 P + E + + +P P CP L + Q +P +RP+F + Sbjct 444 RVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEVMEQAWRLDPEERPTFEYL 496 >sp|G5EE56|SRC1_CAEEL Tyrosine protein-kinase src-1 OS=Caenorhabditis elegans OX=6239 GN=src-1 PE=1 SV=1 Length=533 Score = 129 bits (324), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 92/272 (34%), Positives = 135/272 (50%), Gaps = 31/272 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LG+G+FG+V + G E VA+K +K G + QE I++ H +++ Sbjct 266 RKLGDGNFGEVWYGKWR----GIVE-VAIKTMKP--GTMSPEAFLQEAQIMKQCDHPNLV 318 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQH 1018 K C E+ ++ EY+ GSL YL ++G+ L+ A QI GM YL + Sbjct 319 KLYAVCTR--EEPFYIITEYMINGSLLQYLRTDGSTLGIQALVDMAAQIANGMMYLEERK 376 Query 1019 YIHRDLAARNVLLDNDR----LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 +HRDLAARNVL+ + +VK+ DFGLA+ + E + Y R P+ W APE Sbjct 377 LVHRDLAARNVLVGDKISGVPVVKVADFGLARKLME-EDIYEARTGAKFPIKWTAPEAAT 435 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 F SDVWS+G+ LYE++T Q P M + E +E G R+ Sbjct 436 CGNFTVKSDVWSYGILLYEIMT---KGQVPYPG-----------MHNREVVEQVELGYRM 481 Query 1135 PRPDKCPCEVY-HLMKNCWETEASFRPTFENL 1165 P P CP ++Y ++ CW+ RPTF+ L Sbjct 482 PMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTL 513 Score = 91.7 bits (226), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 64/235 (27%), Positives = 109/235 (46%), Gaps = 15/235 (6%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 + V +K + P AF + A +M Q H +L ++ VC R ++TEY+ +G L Sbjct 285 VEVAIKTMKPGTMSPE-AFLQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLL 343 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +LR + + + + +A Q+A+ + YLE + LVH ++ RN+L +G P +K Sbjct 344 QYLRTDGSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVL---VGDKISGVPVVK 400 Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 ++D G+ + + R I W APE G + + D W +G L EI Sbjct 401 VADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCG--NFTVKSDVWSYGILLYEIMTK 458 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ--LATLTSQCLTYEPTQRPSFRTI 862 G+ P E + +R+P P CP+ + +C P +RP+F T+ Sbjct 459 GQVPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPDRRPTFDTL 513 >sp|P42680|TEC_HUMAN Tyrosine-protein kinase Tec OS=Homo sapiens OX=9606 GN=TEC PE=1 SV=2 Length=631 Score = 130 bits (327), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 89/277 (32%), Positives = 136/277 (49%), Gaps = 30/277 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +R+LG G FG V L + VA+KA++ G + +E ++ L H + Sbjct 373 MRELGSGLFGVVRLGKWRAQYK-----VAIKAIRE--GAMCEEDFIEEAKVMMKLTHPKL 425 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQ 1017 ++ G C Q K + +V E++ G L ++L + ++ LL Q +CEGM YL Sbjct 426 VQLYGVCTQQ--KPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERN 483 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +IHRDLAARN L+ +VK+ DFG+A+ V + Y PV W PE + Sbjct 484 SFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQ--YTSSSGAKFPVKWCPPEVFNYSR 541 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFGV ++E+ T + P K+ T + ++ RG RL +P Sbjct 542 FSSKSDVWSFGVLMWEVFTE---GRMPFEKY-----------TNYEVVTMVTRGHRLYQP 587 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 VY +M CW+ + RP+FE+L L+T+ E Sbjct 588 KLASNYVYEVMLRCWQEKPEGRPSFEDL---LRTIDE 621 Score = 94.4 bits (233), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 59/222 (27%), Positives = 102/222 (46%), Gaps = 16/222 (7%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F E A +M +++H L ++GVC + +VTE++E G L +LR+ +GH + + Sbjct 410 FIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSM 469 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 Q + + YLE + +H ++ RN L++ G+ +K+SD G+ L + Sbjct 470 CQDVCEGMEYLERNSFIHRDLAARNCLVSEAGV-------VKVSDFGMARYVLDDQYTSS 522 Query 775 R-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 + W PE + S+ D W FG + E+ +G P + + E R Sbjct 523 SGAKFPVKWCPPEVF--NYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTR 580 Query 830 QHRLPEPSCPQ--LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 HRL +P + + +C +P RPSF +LR + L Sbjct 581 GHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDEL 622 >sp|Q13470|TNK1_HUMAN Non-receptor tyrosine-protein kinase TNK1 OS=Homo sapiens OX=9606 GN=TNK1 PE=1 SV=3 Length=666 Score = 130 bits (327), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 96/277 (35%), Positives = 136/277 (49%), Gaps = 29/277 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-----WKQEIDILRTLYHE 957 LG G FG V + G VAVK+L+ GP+ G + +E+ ++ L H Sbjct 122 LGSGCFGVVHRGLWT-LPSGKSVPVAVKSLR--VGPEGPMGTELGDFLREVSVMMNLEHP 178 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAY 1013 H+++ G Q LQ+VME PLGSL L P + +A L LF +Q+ MAY Sbjct 179 HVLRLHGLVLGQ---PLQMVMELAPLGSLHARLTAPAPTPPLLVALLCLFLRQLAGAMAY 235 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 L A+ +HRDLA RN+LL + R +K+ DFGL + + Y + P W APE L Sbjct 236 LGARGLVHRDLATRNLLLASPRTIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESL 295 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + F ASDVW FGVTL+E+ + + + +L L + LE R Sbjct 296 RHGAFSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLIL--------------QRLEDRAR 341 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 LPRP C +Y L CW + RP+F +L +L+ Sbjct 342 LPRPPLCSRALYSLALRCWAPHPADRPSFSHLEGLLQ 378 Score = 69.7 bits (169), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 71/217 (33%), Positives = 99/217 (46%), Gaps = 23/217 (11%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F S+M + H H+ +HG+ + P MV E G L L P+ ++ Sbjct 165 FLREVSVMMNLEHPHVLRLHGLVLGQPLQ-MVMELAPLGSLHARLTAPAPTPPLLVALLC 223 Query 715 A--QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV--GLGALSRE 770 +QLA A++YL + LVH ++ RN+LLA + IK++D G+ LG +R Sbjct 224 LFLRQLAGAMAYLGARGLVHRDLATRNLLLA-------SPRTIKVADFGLVRPLGG-ARG 275 Query 771 ERVERIP------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 V P W APE L GA S+A D W FG TL E+ GE P P Sbjct 276 RYVMGGPRPIPYAWCAPESLRHGA--FSSASDVWMFGVTLWEMFSGGEEPWAGVPPYLIL 333 Query 825 HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSF 859 + + RLP P C + L +L +C P RPSF Sbjct 334 QRLEDRARLPRPPLCSRALYSLALRCWAPHPADRPSF 370 >sp|P08922|ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3 Length=2347 Score = 132 bits (332), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 97/278 (35%), Positives = 139/278 (50%), Gaps = 32/278 (12%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG G FG+V D G+GE+ VAVK LK Q + + +E ++ H +I+ Sbjct 1951 LGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNIL 2010 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--------AQLLLFAQQICEGMA 1012 K G C + +++E + G L YL + + L+ I +G Sbjct 2011 KQLGVCLLNEPQ--YIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCV 2068 Query 1013 YLHAQHYIHRDLAARNVLLD-----NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 YL H+IHRDLAARN L+ + R+VKIGDFGLA+ + + ++YYR R +G PV W Sbjct 2069 YLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYK-NDYYRKRGEGLLPVRW 2127 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE L + F SDVWSFG+ ++E+LT Q P A + VL Sbjct 2128 MAPESLMDGIFTTQSDVWSFGILIWEILTL--GHQPYP---------AHSNLDVLN---Y 2173 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 ++ G RL P CP ++++LM CW E RPTF + Sbjct 2174 VQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRI 2211 Score = 83.6 bits (205), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 69/247 (28%), Positives = 113/247 (46%), Gaps = 21/247 (9%) Query 636 ELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 E++V +K L D + F + A LMS+ +H ++ GVC+ ++ E +E G Sbjct 1974 EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGD 2033 Query 695 LDVWLRRERGHV------PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 L +LR+ R + + + ++ YLE + +H ++ RN L++ + Sbjct 2034 LLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVS---VK 2090 Query 749 EGTSP-FIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFG 801 + TSP +K+ D G+ + +R + W+APE L G +T D W FG Sbjct 2091 DYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGI--FTTQSDVWSFG 2148 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 + EI G P + S + ++ Q RL P +CP L L +QC EP QRP+F Sbjct 2149 ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTF 2208 Query 860 RTILRDL 866 I L Sbjct 2209 HRIQDQL 2215 >sp|Q8CBF3|EPHB1_MOUSE Ephrin type-B receptor 1 OS=Mus musculus OX=10090 GN=Ephb1 PE=1 SV=1 Length=984 Score = 131 bits (330), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 82/279 (29%), Positives = 141/279 (51%), Gaps = 23/279 (8%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTL 954 ++K +G G FG+V Y G E+ VA+K LKA + R + E I+ Sbjct 618 FVKIEEVIGAGEFGEV--YKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQF 675 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMA 1012 H +II+ +G + + ++ E++ G+L +L ++ + QL+ + I GM Sbjct 676 DHPNIIRLEGVVTKS--RPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMK 733 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAP 1070 YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G PV W AP Sbjct 734 YLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAP 793 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E + KF ASDVWS+G+ ++E+++ + M+ + +E+ Sbjct 794 EAIAYRKFTSASDVWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIEQ 839 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 RLP P CP ++ LM +CW+ + + RP F ++ L Sbjct 840 DYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTL 878 Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 81/315 (26%), Positives = 141/315 (45%), Gaps = 50/315 (16%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653 +G G VY+GRL++ PG+ +E+ V +K L + + Sbjct 625 IGAGEFGEVYKGRLKL------------------PGK---REIYVAIKTLKAGYSEKQRR 663 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F AS+M Q H ++ + GV + +++TE++E+G LD +LR+ G + + Sbjct 664 DFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVG 723 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 + + +A+ + YL N VH ++ RNIL+ ++ K+SD GL +++ Sbjct 724 MLRGIAAGMKYLSEMNYVHRDLAARNILV-------NSNLVCKVSD--FGLSRYLQDDTS 774 Query 774 E---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + +IP W APE + ++A D W +G + E+ GE P S + Sbjct 775 DPTYTSSLGGKIPVRWTAPEAI--AYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQD 832 Query 823 KEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVL 878 + ++ +RLP P CP L L C + RP F I+ L ++ P +L V Sbjct 833 VINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVA 892 Query 879 TVN--PDSPASDPTV 891 T+ P P D ++ Sbjct 893 TITAVPSQPLLDRSI 907 >sp|P09759|EPHB1_RAT Ephrin type-B receptor 1 OS=Rattus norvegicus OX=10116 GN=Ephb1 PE=1 SV=2 Length=984 Score = 131 bits (330), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 83/279 (30%), Positives = 142/279 (51%), Gaps = 23/279 (8%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTL 954 ++K +G G FG+V Y G E+ VA+K LKA + R + E I+ Sbjct 618 FVKIEEVIGAGEFGEV--YKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQF 675 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMA 1012 H +II+ +G + + ++ E++ G+L +L ++ + QL+ + I GM Sbjct 676 DHPNIIRLEGVVTKS--RPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMK 733 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAP 1070 YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G PV W AP Sbjct 734 YLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAP 793 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E + KF ASDVWS+G+ ++E+++ + P M+ + +E+ Sbjct 794 EAIAYRKFTSASDVWSYGIVMWEVMSF---GERP-----------YWDMSNQDVINAIEQ 839 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 RLP P CP ++ LM +CW+ + + RP F ++ L Sbjct 840 DYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTL 878 Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 81/315 (26%), Positives = 141/315 (45%), Gaps = 50/315 (16%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653 +G G VY+GRL++ PG+ +E+ V +K L + + Sbjct 625 IGAGEFGEVYKGRLKL------------------PGK---REIYVAIKTLKAGYSEKQRR 663 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F AS+M Q H ++ + GV + +++TE++E+G LD +LR+ G + + Sbjct 664 DFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVG 723 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 + + +A+ + YL N VH ++ RNIL+ ++ K+SD GL +++ Sbjct 724 MLRGIAAGMKYLSEMNYVHRDLAARNILV-------NSNLVCKVSD--FGLSRYLQDDTS 774 Query 774 E---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + +IP W APE + ++A D W +G + E+ GE P S + Sbjct 775 DPTYTSSLGGKIPVRWTAPEAI--AYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQD 832 Query 823 KEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVL 878 + ++ +RLP P CP L L C + RP F I+ L ++ P +L V Sbjct 833 VINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVA 892 Query 879 TVN--PDSPASDPTV 891 T+ P P D ++ Sbjct 893 TITAVPSQPLLDRSI 907 >sp|P09769|FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo sapiens OX=9606 GN=FGR PE=1 SV=2 Length=529 Score = 128 bits (322), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 89/273 (33%), Positives = 131/273 (48%), Gaps = 29/273 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LG G FG V L ++ + VAVK LK G + +E +++ L H+ ++ Sbjct 267 RRLGTGCFGDVWLGTWNGSTK-----VAVKTLKP--GTMSPKAFLEEAQVMKLLRHDKLV 319 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQ 1017 + E+ + +V E++ GSL D+L + L QL+ A Q+ EGMAY+ Sbjct 320 QLYAVVS---EEPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERM 376 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +YIHRDL A N+L+ KI DFGLA+ + + + Y + P+ W APE + Sbjct 377 NYIHRDLRAANILVGERLACKIADFGLARLIKD--DEYNPCQGSKFPIKWTAPEAALFGR 434 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFG+ L EL+T I M + E +E+G +P P Sbjct 435 FTIKSDVWSFGILLTELITKGR--------------IPYPGMNKREVLEQVEQGYHMPCP 480 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 CP +Y M+ W + RPTFE L L+ Sbjct 481 PGCPASLYEAMEQTWRLDPEERPTFEYLQSFLE 513 Score = 70.1 bits (170), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 80/313 (26%), Positives = 129/313 (41%), Gaps = 49/313 (16%) Query 560 NLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEG 619 NL+I P+TL L++ ++ + + IT LG G +V+ G GS Sbjct 235 NLLIAPCTIMKPQTLGLAKDAWE-ISRSSITLERRLGTGCFGDVWLGTWN--GS------ 285 Query 620 KMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR 679 +V +K L P AF E A +M + H L ++ V Sbjct 286 -----------------TKVAVKTLKPGTMS-PKAFLEEAQVMKLLRHDKLVQLYAVVSE 327 Query 680 GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGR 738 P I VTE++ HG L +L+ G ++V +A Q+A ++Y+E N +H ++ Sbjct 328 EPIYI-VTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAA 386 Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSL 791 NIL+ G K++D GL L +++ I W APE G ++ Sbjct 387 NILV-------GERLACKIAD--FGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGRFTI 437 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCL 849 + D W FG L E+ G P + E ++ + +P P CP L Q Sbjct 438 KS--DVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTW 495 Query 850 TYEPTQRPSFRTI 862 +P +RP+F + Sbjct 496 RLDPEERPTFEYL 508 >sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo sapiens OX=9606 GN=EPHB1 PE=1 SV=1 Length=984 Score = 131 bits (329), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 82/279 (29%), Positives = 141/279 (51%), Gaps = 23/279 (8%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTL 954 ++K +G G FG+V Y G E+ VA+K LKA + R + E I+ Sbjct 618 FVKIEEVIGAGEFGEV--YKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQF 675 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMA 1012 H +II+ +G + + ++ E++ G+L +L ++ + QL+ + I GM Sbjct 676 DHPNIIRLEGVVTKS--RPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMK 733 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAP 1070 YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G PV W AP Sbjct 734 YLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAP 793 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E + KF ASDVWS+G+ ++E+++ + M+ + +E+ Sbjct 794 EAIAYRKFTSASDVWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIEQ 839 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 RLP P CP ++ LM +CW+ + + RP F ++ L Sbjct 840 DYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTL 878 Score = 94.7 bits (234), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 81/315 (26%), Positives = 141/315 (45%), Gaps = 50/315 (16%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653 +G G VY+GRL++ PG+ +E+ V +K L + + Sbjct 625 IGAGEFGEVYKGRLKL------------------PGK---REIYVAIKTLKAGYSEKQRR 663 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F AS+M Q H ++ + GV + +++TE++E+G LD +LR+ G + + Sbjct 664 DFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVG 723 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 + + +A+ + YL N VH ++ RNIL+ ++ K+SD GL +++ Sbjct 724 MLRGIAAGMKYLAEMNYVHRDLAARNILV-------NSNLVCKVSD--FGLSRYLQDDTS 774 Query 774 E---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + +IP W APE + ++A D W +G + E+ GE P S + Sbjct 775 DPTYTSSLGGKIPVRWTAPEAI--AYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQD 832 Query 823 KEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVL 878 + ++ +RLP P CP L L C + RP F I+ L ++ P +L V Sbjct 833 VINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVA 892 Query 879 TVN--PDSPASDPTV 891 T+ P P D ++ Sbjct 893 TITAVPSQPLLDRSI 907 >sp|Q91736|EPB1B_XENLA Ephrin type-B receptor 1-B (Fragment) OS=Xenopus laevis OX=8355 GN=ephb1-b PE=1 SV=1 Length=902 Score = 130 bits (328), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 73/247 (30%), Positives = 129/247 (52%), Gaps = 20/247 (8%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VA+K LKA + R + E I+ H +II+ +G + + ++ E++ G+L Sbjct 566 VAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGAL 623 Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL Sbjct 624 DSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGL 683 Query 1045 AKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 ++ + + Y G PV W APE ++ KF ASDVWS+G+ ++E++++ + Sbjct 684 SRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIRYRKFTSASDVWSYGIVMWEVMSYGER-- 741 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 M+ + +E+ RLP P CP ++ LM +CW+ + + RP F Sbjct 742 ------------PYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRF 789 Query 1163 ENLIPIL 1169 ++ L Sbjct 790 GEIVNTL 796 Score = 90.5 bits (223), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 80/315 (25%), Positives = 140/315 (44%), Gaps = 50/315 (16%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653 +G G VY+GRL++ P + +E+ V +K L + + Sbjct 543 IGAGEFGEVYKGRLKL------------------PSK---REISVAIKTLKAGYSEKQRR 581 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F AS+M Q H ++ + GV + +++TE++E+G LD +LR+ G + + Sbjct 582 DFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVG 641 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 + + +A+ + YL N VH ++ RNIL+ ++ K+SD GL +++ Sbjct 642 MLRGIAAGMKYLSEMNYVHRDLAARNILV-------NSNLVCKVSD--FGLSRYLQDDTS 692 Query 774 E---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + +IP W APE + ++A D W +G + E+ GE P S + Sbjct 693 DPTYTSSLGGKIPVRWTAPEAI--RYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQD 750 Query 823 KEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVL 878 + ++ +RLP P CP L L C + RP F I+ L ++ P +L V Sbjct 751 VINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFGEIVNTLDKMIRNPASLKTVA 810 Query 879 TV--NPDSPASDPTV 891 T+ P P D ++ Sbjct 811 TIPAVPSQPLLDRSI 825 >sp|Q91048|PTK7_CHICK Inactive tyrosine-protein kinase 7 OS=Gallus gallus OX=9031 GN=PTK7 PE=2 SV=1 Length=1051 Score = 130 bits (328), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 92/308 (30%), Positives = 141/308 (46%), Gaps = 29/308 (9%) Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE-MVAVKA 931 NL + A D F + L+ I LG G FG+V L D GE +V VK+ Sbjct 753 NLGSSSGASKRHSARDKMHFPRSNLQTITTLGRGEFGEVFLAKAKGAEDAEGEALVLVKS 812 Query 932 LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL- 990 L+ Q + +++E ++ L H ++++ G C + + +V+EYV LG L+ +L Sbjct 813 LQTR-DEQLQLDFRREAEMFGKLNHVNVVRLLGLCREA--EPHYMVLEYVDLGDLKQFLR 869 Query 991 ---------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 + + Q+ GM +L ++HRDLAARN L+ R VK+ Sbjct 870 ISKSKDESLKPQPLSTKHKVSLCTQVALGMEHLSNGRFVHRDLAARNCLVSAQRQVKVSA 929 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 L+K V EYY R+ P+ W PE + E +F SDVWSFGV ++E+ T + Sbjct 930 LSLSKDV-YNSEYYHFRQ-AWIPLRWMPPEAVLEDEFSTKSDVWSFGVLMWEVFTQGEMP 987 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 +P L G+ G+ +LP+P+ CP + LM+ CW RP+ Sbjct 988 YAPLADDEVLAGLKSGKT-------------KLPQPEGCPSRLTKLMQRCWAPSPKDRPS 1034 Query 1162 FENLIPIL 1169 F L L Sbjct 1035 FSELAAAL 1042 Score = 70.9 bits (172), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 64/251 (25%), Positives = 105/251 (42%), Gaps = 21/251 (8%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 D E V++K L + L F A + +++H ++ + G+C + MV EY Sbjct 799 AEDAEGEALVLVKSLQTRDEQLQLDFRREAEMFGKLNHVNVVRLLGLCREAEPHYMVLEY 858 Query 690 VEHGPLDVWLRRERGH------VPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNIL 741 V+ G L +LR + P++ K V+ Q+A + +L N VH ++ RN L Sbjct 859 VDLGDLKQFLRISKSKDESLKPQPLSTKHKVSLCTQVALGMEHLSNGRFVHRDLAARNCL 918 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGA---NSLSTAMDKW 798 ++ +K+S + + E R W+ +P A + ST D W Sbjct 919 VS-------AQRQVKVSALSLSKDVYNSEYYHFRQAWIPLRWMPPEAVLEDEFSTKSDVW 971 Query 799 GFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQ 855 FG + E+ GE P + E + +LP+P CP +L L +C P Sbjct 972 SFGVLMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLPQPEGCPSRLTKLMQRCWAPSPKD 1031 Query 856 RPSFRTILRDL 866 RPSF + L Sbjct 1032 RPSFSELAAAL 1042 >sp|P14238|FES_FELCA Tyrosine-protein kinase Fes/Fps OS=Felis catus OX=9685 GN=FES PE=3 SV=2 Length=820 Score = 130 bits (326), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 93/310 (30%), Positives = 149/310 (48%), Gaps = 24/310 (8%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 QP + +N P D V + L +G G+FG+V + D T +VAV Sbjct 533 QPLTKKSGIVLNRAVP-KDKWVLNHEDLVLGEQIGRGNFGEV--FSGRLRADNT--LVAV 587 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K+ + P ++ + QE IL+ H +I++ G C + + + +VME V G + Sbjct 588 KSCRETLPPDIKAKFLQEAKILKQYSHPNIVRLIGVCTQK--QPIYIVMELVQGGDFLTF 645 Query 990 LPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 L + + LL GM YL ++ IHRDLAARN L+ ++KI DFG+++ Sbjct 646 LRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSRE 705 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 +G Y PV W APE L ++ SDVWSFG+ L+E + +S P Sbjct 706 EADGI-YAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFS-LGASPYP--- 760 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 ++ + E +E+G RLP P+ CP V+ LM+ CW E RP+F + Sbjct 761 ----------NLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQ 810 Query 1168 ILKTVHEKYQ 1177 L+++ ++++ Sbjct 811 ELQSIRKRHR 820 Score = 99.4 bits (246), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 103/376 (27%), Positives = 161/376 (43%), Gaps = 67/376 (18%) Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562 R F IE D + LEG G F S+ L LLR+ QP + I Sbjct 500 RHFIIESADNLYRLEGDG--FASI----PLLVDHLLRS------------QQPLTKKSGI 541 Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 ++ RA P+ + ++ +++ +G+G V+ GRLR + + Sbjct 542 VLN--RAVPKDKWV-------LNHEDLVLGEQIGRGNFGEVFSGRLRADNT--------- 583 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 LV ++ + L P DI F + A ++ Q SH ++ + GVC + Sbjct 584 ----LVA-------VKSCRETLPP---DIKAKFLQEAKILKQYSHPNIVRLIGVCTQKQP 629 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +V E V+ G +LR E + M + + A+ + YLE+K +H ++ RN L+ Sbjct 630 IYIVMELVQGGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLV 689 Query 743 ARLGLAEGTSPFIKLSDPGV------GLGALSREERVERIPWLAPECLPGGANSLSTAMD 796 + +K+SD G+ G+ A S R + W APE L G S+ D Sbjct 690 TEKNV-------LKISDFGMSREEADGIYAASGGLRQVPVKWTAPEALNYG--RYSSESD 740 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPT 854 W FG L E G +P + S + F ++ RLP P CP + L QC YEP Sbjct 741 VWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPG 800 Query 855 QRPSFRTILRDLTRLQ 870 QRPSF I ++L ++ Sbjct 801 QRPSFSAIYQELQSIR 816 >sp|Q22146|FRK1_CAEEL Fer-related kinase 1 OS=Caenorhabditis elegans OX=6239 GN=frk-1 PE=1 SV=1 Length=390 Score = 125 bits (313), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 80/277 (29%), Positives = 137/277 (49%), Gaps = 27/277 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 + LGEG FG V + D G + VAVK ++A+ + R + +E ++R H+H++ Sbjct 135 KKLGEGAFGDVFIAELD---QGGKQEVAVKTMRAEATREARLRFMKEARLMRKYQHKHVV 191 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 K G E L +VMEY P GSL +L ++ + L + L F + +G+AYL I Sbjct 192 KLIGVA--IHEHPLMIVMEYCPNGSLLSHLKKNKVSLIEKLRFTTEAADGIAYLERSKCI 249 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVFWYAPECLKEYKF 1078 HRD+AARN LL +KI DFG++ E ++++ P+ W APE ++E + Sbjct 250 HRDIAARNCLLSAKNELKISDFGMSDNKDE------IKDETLEKVPIKWLAPETMQEKVY 303 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 + +D+W+FGV ++E+ + D ++ P G + +++ R+ PD Sbjct 304 THKTDIWTFGVLVWEI--YSDGAEPYP-----------GLTKIQTRAKIVVNDYRMKMPD 350 Query 1139 KC-PCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 P + CW+ R T +++ L+ +E Sbjct 351 GTHPTVADVVTGTCWQKNPEKRSTMDSIHKKLREFYE 387 Score = 78.6 bits (192), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 64/253 (25%), Positives = 117/253 (46%), Gaps = 25/253 (10%) Query 625 DPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 D + D+G + V +K + + + L F + A LM + H H+ + GV + Sbjct 144 DVFIAELDQGGKQEVAVKTMRAEATREARLRFMKEARLMRKYQHKHVVKLIGVAIHEHPL 203 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 ++V EY +G L L++ + V + K+ + A ++YLE +H ++ RN LL+ Sbjct 204 MIVMEYCPNGSLLSHLKKNK--VSLIEKLRFTTEAADGIAYLERSKCIHRDIAARNCLLS 261 Query 744 RLGLAEGTSPFIKLSDPGVGLGALS-REERVERIP--WLAPECLPGGANSLSTAMDKWGF 800 +K+SD G+ ++E +E++P WLAPE + + T D W F Sbjct 262 -------AKNELKISDFGMSDNKDEIKDETLEKVPIKWLAPETMQEKVYTHKT--DIWTF 312 Query 801 GATLLEICFDGEAP------LQSRSPSEKEHFYQRQHRLPEPSCPQLA-TLTSQCLTYEP 853 G + EI DG P +Q+R+ + + ++P+ + P +A +T C P Sbjct 313 GVLVWEIYSDGAEPYPGLTKIQTRAKIVVNDY---RMKMPDGTHPTVADVVTGTCWQKNP 369 Query 854 TQRPSFRTILRDL 866 +R + +I + L Sbjct 370 EKRSTMDSIHKKL 382 >sp|Q8BYG9|EPHAA_MOUSE Ephrin type-A receptor 10 OS=Mus musculus OX=10090 GN=Epha10 PE=2 SV=2 Length=1007 Score = 130 bits (327), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 89/278 (32%), Positives = 128/278 (46%), Gaps = 23/278 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LG G FG + C G E+ VAV L+ C R + E L H HI Sbjct 648 KSLGAGRFGTLCCGCLQ--LPGRQELPVAVHTLRDGCSDSQRLSFLAEALTLGQFDHSHI 705 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQ 1017 ++ +G L +V EY+ LG+L D+L H L AQL+ + M YL Sbjct 706 VRLEGVVTRG--NPLMIVTEYMNLGALDDFLRHHEGELVAAQLMGLLPGLASAMKYLSEM 763 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 Y+HR LAAR VL+ + L KI FG + + E G SP W APE L+ Sbjct 764 GYVHRGLAARRVLVSSGLLCKISGFG--RGPRDRAEAVYTTMSGRSPALWAAPETLQFGH 821 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F ASDVWSFG+ ++E++ + M+ + + +E G RLP P Sbjct 822 FSSASDVWSFGIVMWEVMAFGER--------------PYWDMSGQDVIKAVEDGFRLPPP 867 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 CP +++ LM CW+ + S RP F + IL + ++ Sbjct 868 RNCPSQLHRLMLECWQKDPSERPRFSQIHSILSKMGQE 905 Score = 104 bits (260), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 91/275 (33%), Positives = 127/275 (46%), Gaps = 28/275 (10%) Query 628 VPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 +PGR QEL V + L D L+F A + Q H+H+ + GV RG ++V Sbjct 665 LPGR---QELPVAVHTLRDGCSDSQRLSFLAEALTLGQFDHSHIVRLEGVVTRGNPLMIV 721 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TEY+ G LD +LR G + A M + LASA+ YL VH + R +L++ G Sbjct 722 TEYMNLGALDDFLRHHEGELVAAQLMGLLPGLASAMKYLSEMGYVHRGLAARRVLVSS-G 780 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-----ERIP--WLAPECLPGGANSLSTAMDKWG 799 L K+S G G G R E V R P W APE L G S+A D W Sbjct 781 L------LCKIS--GFGRGPRDRAEAVYTTMSGRSPALWAAPETLQFG--HFSSASDVWS 830 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRP 857 FG + E+ GE P S + + RLP P +CP QL L +C +P++RP Sbjct 831 FGIVMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPSQLHRLMLECWQKDPSERP 890 Query 858 SFRTILRDLTRL----QPHNLADVLTVNPDSPASD 888 F I L+++ +P A + P +P +D Sbjct 891 RFSQIHSILSKMGQEPEPSKCASTTCLRPPTPLAD 925 >sp|A0JM20|TYRO3_XENTR Tyrosine-protein kinase receptor TYRO3 OS=Xenopus tropicalis OX=8364 GN=tyro3 PE=2 SV=1 Length=881 Score = 130 bits (326), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 92/278 (33%), Positives = 134/278 (48%), Gaps = 30/278 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEH 958 R LG+G FG V D T + VAVK LKA+ C + +E ++ H + Sbjct 507 RTLGKGEFGSVR-EAQLKMEDDTMQKVAVKMLKAEIFCSSDIEE-FLREAAFMKEFDHPN 564 Query 959 IIKYKGCCEDQGEKSL----QLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFAQQI 1007 + K G K +++ ++ G L +L IG + L+ F I Sbjct 565 VCKLIGVSLRSRTKGRLPVPMVILPFMKHGDLHTFLLMSRIGEEPIALPIQTLVRFMIDI 624 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 C GM YL ++++IHRDLA RN +L+ D V + DFGL+K + G +YYR PV W Sbjct 625 CSGMEYLSSKNFIHRDLATRNCMLNEDMTVCVADFGLSKKIYSG-DYYRQGCASKLPVKW 683 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 A E L + + SDVW+FGVTL+E++T Q+P G+ + + Sbjct 684 LALESLADNVYTVHSDVWAFGVTLWEIVTR---GQTP------YAGVENSE-----IYSY 729 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L G RL +P C E+Y +M CW TE RP+F +L Sbjct 730 LTAGNRLKQPPDCLDELYEMMCQCWITEPKRRPSFVDL 767 Score = 74.3 bits (181), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 83/314 (26%), Positives = 132/314 (42%), Gaps = 57/314 (18%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S+L + Q++ T LG+G +V E +L KM+D D Q+ Sbjct 491 SKLKDVLIQQQQFTLGRTLGKGEFGSVREAQL-----------KMED--------DTMQK 531 Query 637 LRV-VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEY 689 + V +LK DI F A+ M + H ++ + GV +R P +++ + Sbjct 532 VAVKMLKAEIFCSSDIE-EFLREAAFMKEFDHPNVCKLIGVSLRSRTKGRLPVPMVILPF 590 Query 690 VEHGPLDVWLRRER-GHVPMAWKMVVAQQ----LASALSYLENKNLVHGNVCGRNILL-- 742 ++HG L +L R G P+A + + + S + YL +KN +H ++ RN +L Sbjct 591 MKHGDLHTFLLMSRIGEEPIALPIQTLVRFMIDICSGMEYLSSKNFIHRDLATRNCMLNE 650 Query 743 ------ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP--WLAPECLPGGANSLSTA 794 A GL++ + G R+ ++P WLA E L N + Sbjct 651 DMTVCVADFGLSKK-----------IYSGDYYRQGCASKLPVKWLALESL--ADNVYTVH 697 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYE 852 D W FG TL EI G+ P SE + +RL +P +L + QC E Sbjct 698 SDVWAFGVTLWEIVTRGQTPYAGVENSEIYSYLTAGNRLKQPPDCLDELYEMMCQCWITE 757 Query 853 PTQRPSFRTILRDL 866 P +RPSF + R L Sbjct 758 PKRRPSFVDLKRRL 771 >sp|P16591|FER_HUMAN Tyrosine-protein kinase Fer OS=Homo sapiens OX=9606 GN=FER PE=1 SV=2 Length=822 Score = 129 bits (325), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 91/277 (33%), Positives = 136/277 (49%), Gaps = 29/277 (10%) Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG+G+FG+V Y T D T VAVK K D + + + QE IL+ H +I+K Sbjct 569 LGKGNFGEV----YKGTLKDKTS--VAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVK 622 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHY 1019 G C + + + ++ME V G +L R + L QL+ F+ GM YL +++ Sbjct 623 LIGVCTQR--QPVYIIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLESKNC 680 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRDLAARN L+ + ++KI DFG+++ G Y P+ W APE L ++ Sbjct 681 IHRDLAARNCLVGENNVLKISDFGMSRQEDGG--VYSSSGLKQIPIKWTAPEALNYGRYS 738 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA-QGQMTVLRLTELLERGERLPRPD 1138 SDVWSFG+ L+E + +G+ MT + E +ERG R+ P Sbjct 739 SESDVWSFGILLWETFS---------------LGVCPYPGMTNQQAREQVERGYRMSAPQ 783 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 CP ++ +M CW+ + RP F L L + K Sbjct 784 HCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRK 820 Score = 89.7 bits (221), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 73/280 (26%), Positives = 127/280 (45%), Gaps = 40/280 (14%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LG+G VY+G L+ + S + K D +P QEL++ Sbjct 569 LGKGNFGEVYKGTLKDKTSVAVKTCKED-----LP-----QELKI--------------K 604 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F + A ++ Q H ++ + GVC + ++ E V G +LRR++ + + + Sbjct 605 FLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQLVKF 664 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---GALSREE 771 + A+ + YLE+KN +H ++ RN L+ G + +K+SD G+ G + Sbjct 665 SLDAAAGMLYLESKNCIHRDLAARNCLV-------GENNVLKISDFGMSRQEDGGVYSSS 717 Query 772 RVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 +++IP W APE L G S+ D W FG L E G P + + +R Sbjct 718 GLKQIPIKWTAPEALNYG--RYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVER 775 Query 830 QHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLT 867 +R+ P CP+ ++ + +C Y+P RP F + ++LT Sbjct 776 GYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELT 815 >sp|Q91735|EPHB3_XENLA Ephrin type-B receptor 3 OS=Xenopus laevis OX=8355 GN=ephb3 PE=2 SV=1 Length=974 Score = 129 bits (325), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 79/273 (29%), Positives = 134/273 (49%), Gaps = 25/273 (9%) Query 903 LGEGHFGKVSLYCYDPTNDG--TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G FG+V C + VA+K LKA Q R + E I+ H +II Sbjct 615 IGAGEFGEV---CRGKLKQAGRREQFVAIKTLKAGYTEQQRRDFLGEASIMGQFDHPNII 671 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018 + +G + + ++ E++ G+L +L + + QL+ + I GM YL + Sbjct 672 RLEGVVTR--SRPVMILTEFMENGALDSFLRMNDGQFTVIQLVGILRGIASGMKYLSEMN 729 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076 Y+HRDLAARN+L++++ + K+ DFGL++ + Y G P+ W APE + Sbjct 730 YVHRDLAARNILVNSNLVCKVSDFGLSRFLENSRSDPTYTSALGGKIPIRWTAPEAISYR 789 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 KF ASDVWS+G+ ++E++++ + M+ + +E+ RLP Sbjct 790 KFTSASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVINAIEQDYRLPP 835 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P CP ++ LM +CW + + RP F ++ L Sbjct 836 PMDCPSALHQLMLDCWLRDRNLRPKFSQIVSSL 868 Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 68/241 (28%), Positives = 109/241 (45%), Gaps = 25/241 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F AS+M Q H ++ + GV R +++TE++E+G LD +LR G + + + Sbjct 655 FLGEASIMGQFDHPNIIRLEGVVTRSRPVMILTEFMENGALDSFLRMNDGQFTVIQLVGI 714 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + +AS + YL N VH ++ RNIL+ ++ K+SD GL R + Sbjct 715 LRGIASGMKYLSEMNYVHRDLAARNILV-------NSNLVCKVSD--FGLSRFLENSRSD 765 Query 775 ---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 +IP W APE + ++A D W +G + E+ GE P S + Sbjct 766 PTYTSALGGKIPIRWTAPEAI--SYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDV 823 Query 824 EHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 + ++ +RLP P CP L L C + RP F I+ L +L N A + + Sbjct 824 INAIEQDYRLPPPMDCPSALHQLMLDCWLRDRNLRPKFSQIVSSLDKL-IRNAASLKVTS 882 Query 882 P 882 P Sbjct 883 P 883 >sp|P24348|LET23_CAEEL Receptor tyrosine-protein kinase let-23 OS=Caenorhabditis elegans OX=6239 GN=let-23 PE=1 SV=3 Length=1323 Score = 130 bits (326), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 91/274 (33%), Positives = 140/274 (51%), Gaps = 24/274 (9%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LG G FG V Y P ++ VA+K + D Q ++ ++ R L H+++ Sbjct 889 KKLGAGAFGTVFAGIYYPKRAKNVKIPVAIKVFQTD-QSQTDEMLEEATNMFR-LRHDNL 946 Query 960 IKYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHA 1016 +K G C D G L++V Y PLG+L+++L H ++G + +L+ QI GM YL Sbjct 947 LKIIGFCMHDDG---LKIVTIYRPLGNLQNFLKLHKENLGAREQVLYCYQIASGMQYLEK 1003 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 Q +HRDLA RNVL+ V+I DFGL+K + + ++ G + W A E ++ Sbjct 1004 QRVVHRDLATRNVLVKKFNHVEITDFGLSKILKHDADSITIKS-GKVAIKWLAIEIFSKH 1062 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 + +ASDVW+FGVT +E++T QSP QG M+ + L+ G RL + Sbjct 1063 CYTHASDVWAFGVTCWEIITF---GQSP----------YQG-MSTDSIHNFLKDGNRLSQ 1108 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 P C ++Y + CW + RP FE L K Sbjct 1109 PPNCSQDLYQELLRCWMADPKSRPGFEILYERFK 1142 Score = 79.0 bits (193), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 67/242 (28%), Positives = 112/242 (46%), Gaps = 18/242 (7%) Query 629 PGRDRGQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 P R + ++ V +KV D S D L E A+ M ++ H +L + G C+ +V Sbjct 906 PKRAKNVKIPVAIKVFQTDQSQTDEML---EEATNMFRLRHDNLLKIIGFCMHDDGLKIV 962 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 T Y G L +L+ + ++ +++ Q+AS + YLE + +VH ++ RN+L+ + Sbjct 963 TIYRPLGNLQNFLKLHKENLGAREQVLYCYQIASGMQYLEKQRVVHRDLATRNVLVKKFN 1022 Query 747 LAE----GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 E G S +K + + + +V I WLA E + + A D W FG Sbjct 1023 HVEITDFGLSKILKHDADSITI----KSGKVA-IKWLAIEIF--SKHCYTHASDVWAFGV 1075 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCPQ-LATLTSQCLTYEPTQRPSFR 860 T EI G++P Q S +F + +RL + P+C Q L +C +P RP F Sbjct 1076 TCWEIITFGQSPYQGMSTDSIHNFLKDGNRLSQPPNCSQDLYQELLRCWMADPKSRPGFE 1135 Query 861 TI 862 + Sbjct 1136 IL 1137 >sp|Q2MHE4|HT1_ARATH Serine/threonine/tyrosine-protein kinase HT1 OS=Arabidopsis thaliana OX=3702 GN=HT1 PE=1 SV=1 Length=390 Score = 124 bits (311), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 78/254 (31%), Positives = 125/254 (49%), Gaps = 25/254 (10%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 +MV + K + + +K E+ +L L+H +I+++ C + ++ EY+ G Sbjct 113 KMVRIPTHKEETRAKLEQQFKSEVALLSRLFHPNIVQFIAAC--KKPPVYCIITEYMSQG 170 Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 +LR YL + +S+ + +L A I GM YLH+Q IHRDL + N+LL+++ VK+ D Sbjct 171 NLRMYLNKKEPYSLSIETVLRLALDISRGMEYLHSQGVIHRDLKSNNLLLNDEMRVKVAD 230 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVF-WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100 FG + + E G+ + W APE +KE + DV+SFG+ L+EL T Sbjct 231 FGTSCLETQCRE-----AKGNMGTYRWMAPEMIKEKPYTRKVDVYSFGIVLWELTTA--- 282 Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 + QG V + E+ ER P P C + HL+K CW S RP Sbjct 283 -----------LLPFQGMTPVQAAFAVAEKNERPPLPASCQPALAHLIKRCWSENPSKRP 331 Query 1161 TFENLIPILKTVHE 1174 F N++ +L+ E Sbjct 332 DFSNIVAVLEKYDE 345 Score = 63.5 bits (153), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 61/250 (24%), Positives = 112/250 (45%), Gaps = 30/250 (12%) Query 635 QELRVVLKVLDPSHHDIALA-----FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 Q V V P+H + A F +L+S++ H ++ C + P ++TEY Sbjct 107 QRAVAVKMVRIPTHKEETRAKLEQQFKSEVALLSRLFHPNIVQFIAACKKPPVYCIITEY 166 Query 690 VEHGPLDVWL-RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + G L ++L ++E + + + +A ++ + YL ++ ++H ++ N+LL Sbjct 167 MSQGNLRMYLNKKEPYSLSIETVLRLALDISRGMEYLHSQGVIHRDLKSNNLLL------ 220 Query 749 EGTSPFIKLSDPGVG-LGALSREER--VERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 +K++D G L RE + + W+APE + + +D + FG L Sbjct 221 -NDEMRVKVADFGTSCLETQCREAKGNMGTYRWMAPEMI--KEKPYTRKVDVYSFGIVLW 277 Query 806 EIC-----FDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEPTQRPS 858 E+ F G P+Q+ ++ R P P SC P LA L +C + P++RP Sbjct 278 ELTTALLPFQGMTPVQAAFA-----VAEKNERPPLPASCQPALAHLIKRCWSENPSKRPD 332 Query 859 FRTILRDLTR 868 F I+ L + Sbjct 333 FSNIVAVLEK 342 >sp|Q9UF33|EPHA6_HUMAN Ephrin type-A receptor 6 OS=Homo sapiens OX=9606 GN=EPHA6 PE=1 SV=3 Length=1036 Score = 129 bits (324), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 94/342 (27%), Positives = 158/342 (46%), Gaps = 70/342 (20%) Query 880 VNPDSPASDPTVFHKRYLKKI--------RDLGEGHFGKVSLYCYDPTND-GTGEM-VAV 929 ++PD+ DP++ + K+I R +G G FG+V C G E+ VA+ Sbjct 607 IDPDT-YEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEV---CSGRLKTPGKREIPVAI 662 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ-------------------- 969 K LK + R + +E I+ H +II+ +G + Sbjct 663 KTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFL 722 Query 970 --------------------GEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQI 1007 + + +V+EY+ GSL +L +H + QL+ + I Sbjct 723 NSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGI 782 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 GM YL Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W Sbjct 783 ASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRW 842 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + KF ASD WS+G+ ++E++++ + P + E+ Q +L Sbjct 843 TAPEAIAYRKFSSASDAWSYGIVMWEVMSY---GERP---YWEM----SNQDVILS---- 888 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 +E G RLP P CP ++ LM +CW+ E + RP F +++ L Sbjct 889 IEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFL 930 Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 88/341 (26%), Positives = 135/341 (40%), Gaps = 70/341 (21%) Query 607 RLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQ 664 R+R+E G E G++ PG+ +E+ V +K L H D F AS+M Q Sbjct 630 RIRIERVIGAGEFGEVCSGRLKTPGK---REIPVAIKTLKGGHMDRQRRDFLREASIMGQ 686 Query 665 VSHTHLAFVHGVCVR------------------------------------------GPE 682 H ++ + GV + G Sbjct 687 FDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRP 746 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 ++V EY+E+G LD +LR+ GH + + + + +AS + YL + VH ++ RNIL+ Sbjct 747 VMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILV 806 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIP--WLAPECLPGGANSLSTAM 795 ++ K+SD G+ E +IP W APE + S+A Sbjct 807 -------NSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAI--AYRKFSSAS 857 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEP 853 D W +G + E+ GE P S + + +RLP P CP L L C E Sbjct 858 DAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKER 917 Query 854 TQRPSFRTILRDLTRL-----QPHNLADVLTVNPDSPASDP 889 RP F I+ L +L H L + + V P+SP P Sbjct 918 NHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGEVP 958 >sp|P07332|FES_HUMAN Tyrosine-protein kinase Fes/Fps OS=Homo sapiens OX=9606 GN=FES PE=1 SV=3 Length=822 Score = 129 bits (323), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 87/277 (31%), Positives = 138/277 (50%), Gaps = 23/277 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G+FG+V + D T +VAVK+ + P ++ + QE IL+ H +I++ Sbjct 567 IGRGNFGEV--FSGRLRADNT--LVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRL 622 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYI 1020 G C + + + +VME V G +L L LL GM YL ++ I Sbjct 623 IGVCTQK--QPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCI 680 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARN L+ ++KI DFG+++ +G Y PV W APE L ++ Sbjct 681 HRDLAARNCLVTEKNVLKISDFGMSREEADG-VYAASGGLRQVPVKWTAPEALNYGRYSS 739 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWSFG+ L+E + +S P ++ + E +E+G RLP P+ C Sbjct 740 ESDVWSFGILLWETFS-LGASPYP-------------NLSNQQTREFVEKGGRLPCPELC 785 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 P V+ LM+ CW E RP+F + L+++ ++++ Sbjct 786 PDAVFRLMEQCWAYEPGQRPSFSTIYQELQSIRKRHR 822 Score = 97.4 bits (241), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 81/285 (28%), Positives = 128/285 (45%), Gaps = 40/285 (14%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 +G+G V+ GRLR + + LV ++ + L P D+ Sbjct 566 QIGRGNFGEVFSGRLRADNT-------------LVA-------VKSCRETLPP---DLKA 602 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F + A ++ Q SH ++ + GVC + +V E V+ G +LR E + + + Sbjct 603 KFLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQ 662 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGAL 767 + A+ + YLE+K +H ++ RN L+ + +K+SD G+ G+ A Sbjct 663 MVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNV-------LKISDFGMSREEADGVYAA 715 Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 S R + W APE L G S+ D W FG L E G +P + S + F Sbjct 716 SGGLRQVPVKWTAPEALNYG--RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFV 773 Query 828 QRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 ++ RLP P CP + L QC YEP QRPSF TI ++L ++ Sbjct 774 EKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQSIR 818 >sp|Q07494|EPHB1_CHICK Ephrin type-B receptor 1 (Fragment) OS=Gallus gallus OX=9031 GN=EPHB1 PE=2 SV=2 Length=984 Score = 129 bits (324), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 81/279 (29%), Positives = 140/279 (50%), Gaps = 23/279 (8%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTL 954 ++K +G G FG+V Y G E+ VA+K LKA + R + E I+ Sbjct 618 FVKIEEVIGAGEFGEV--YKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQF 675 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMA 1012 H +II+ +G + + ++ E++ G+L +L ++ + QL+ + I GM Sbjct 676 DHPNIIRLEGVVTKS--RPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMK 733 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAP 1070 YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G PV W AP Sbjct 734 YLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAP 793 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E + KF ASDVWS+G+ ++E+++ + M+ + +E+ Sbjct 794 EAIAYRKFTSASDVWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIEQ 839 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 RLP P CP ++ LM +CW+ + + RP ++ L Sbjct 840 DYRLPPPMDCPAALHQLMLDCWQKDRNTRPRLAEIVNTL 878 Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 80/315 (25%), Positives = 140/315 (44%), Gaps = 50/315 (16%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653 +G G VY+GRL++ PG+ +E+ V +K L + + Sbjct 625 IGAGEFGEVYKGRLKL------------------PGK---REIYVAIKTLKAGYSEKQRR 663 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F AS+M Q H ++ + GV + +++TE++E+G LD +LR+ G + + Sbjct 664 DFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVG 723 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 + + +A+ + YL N VH ++ RNIL+ ++ K+SD GL +++ Sbjct 724 MLRGIAAGMKYLAEMNYVHRDLAARNILV-------NSNLVCKVSD--FGLSRYLQDDTS 774 Query 774 E---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + +IP W APE + ++A D W +G + E+ GE P S + Sbjct 775 DPTYTSSLGGKIPVRWTAPEAI--AYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQD 832 Query 823 KEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVL 878 + ++ +RLP P CP L L C + RP I+ L ++ P +L V Sbjct 833 VINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNTRPRLAEIVNTLDKMIRNPASLKTVA 892 Query 879 TVN--PDSPASDPTV 891 T+ P P D ++ Sbjct 893 TITAVPSQPLLDRSI 907 >sp|P54758|EPHA6_RAT Ephrin type-A receptor 6 OS=Rattus norvegicus OX=10116 GN=Epha6 PE=2 SV=2 Length=1035 Score = 129 bits (324), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 94/342 (27%), Positives = 158/342 (46%), Gaps = 70/342 (20%) Query 880 VNPDSPASDPTVFHKRYLKKI--------RDLGEGHFGKVSLYCYDPTND-GTGEM-VAV 929 ++PD+ DP++ + K+I R +G G FG+V C G E+ VA+ Sbjct 606 IDPDT-YEDPSLAVHEFEKEIDPSRIRIERVIGAGEFGEV---CSGRLKTPGKREIPVAI 661 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ-------------------- 969 K LK + R + +E I+ H +II+ +G + Sbjct 662 KTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFL 721 Query 970 --------------------GEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQI 1007 + + +V+EY+ GSL +L +H + QL+ + I Sbjct 722 NGIQAPHPVTAGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGI 781 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 GM YL Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W Sbjct 782 ASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRW 841 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + KF ASDVWS+G+ ++E++++ + + E+ Q +L Sbjct 842 TAPEAIAYRKFSSASDVWSYGIVMWEVMSYGER------PYWEM----SNQDVILS---- 887 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 +E G RLP P CP ++ LM +CW+ E + RP F +++ L Sbjct 888 IEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFL 929 Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 88/341 (26%), Positives = 135/341 (40%), Gaps = 70/341 (21%) Query 607 RLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQ 664 R+R+E G E G++ PG+ +E+ V +K L H D F AS+M Q Sbjct 629 RIRIERVIGAGEFGEVCSGRLKTPGK---REIPVAIKTLKGGHMDRQRRDFLREASIMGQ 685 Query 665 VSHTHLAFVHGVCVR------------------------------------------GPE 682 H ++ + GV + G Sbjct 686 FDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNGIQAPHPVTAGGSLPPRIPAGRP 745 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 ++V EY+E+G LD +LR+ GH + + + + +AS + YL + VH ++ RNIL+ Sbjct 746 VMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILV 805 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIP--WLAPECLPGGANSLSTAM 795 ++ K+SD G+ E +IP W APE + S+A Sbjct 806 -------NSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAI--AYRKFSSAS 856 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEP 853 D W +G + E+ GE P S + + +RLP P C P L L C E Sbjct 857 DVWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKER 916 Query 854 TQRPSFRTILRDLTRL-----QPHNLADVLTVNPDSPASDP 889 RP F I+ L +L H L + + V P+SP P Sbjct 917 NHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGDVP 957 >sp|P00544|FGR_FSVGR Tyrosine-protein kinase transforming protein Fgr OS=Feline sarcoma virus (strain Gardner-Rasheed) OX=11775 GN=V-FGR PE=3 SV=1 Length=545 Score = 126 bits (317), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 88/273 (32%), Positives = 129/273 (47%), Gaps = 29/273 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LG G FG V L ++ + VAVK LK G +E I++ L H+ ++ Sbjct 290 RRLGTGCFGDVWLGMWNGSTK-----VAVKTLKP--GTMSPKASLEEAQIMKLLRHDKLV 342 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQ 1017 + E+ + +V E++ GSL ++L + L QL+ A Q+ EGMAY+ Sbjct 343 QLYAVVP---EEPIYIVTEFMCHGSLLEFLKDQEGQDLTLPQLVDMAAQVAEGMAYMERM 399 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 YIHRDL A N+L+ + KI DFGLA+ + + Y R+ P+ W APE + Sbjct 400 DYIHRDLRAANILVGERLVCKIADFGLARLIEDNE--YNPRQGAKFPIKWTAPEAALFGR 457 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFG+ L EL++ + M + E +E G +P P Sbjct 458 FTIKSDVWSFGILLTELISKGR--------------VPYPGMNNREVLEQVEHGYHMPCP 503 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 CP +Y M+ W + RPTFE L L+ Sbjct 504 PGCPASLYEAMEQTWRLDPEERPTFEYLQSFLE 536 Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 61/233 (26%), Positives = 100/233 (43%), Gaps = 19/233 (8%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L P A E A +M + H L ++ V P I VTE++ HG L Sbjct 310 KVAVKTLKPGTMS-PKASLEEAQIMKLLRHDKLVQLYAVVPEEPIYI-VTEFMCHGSLLE 367 Query 698 WLRRERGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ + G ++V +A Q+A ++Y+E + +H ++ NIL+ G K Sbjct 368 FLKDQEGQDLTLPQLVDMAAQVAEGMAYMERMDYIHRDLRAANILV-------GERLVCK 420 Query 757 LSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ E + I W APE G ++ + D W FG L E+ G Sbjct 421 IADFGLARLIEDNEYNPRQGAKFPIKWTAPEAALFGRFTIKS--DVWSFGILLTELISKG 478 Query 812 EAPLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTI 862 P + E + + +P P CP L Q +P +RP+F + Sbjct 479 RVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYL 531 >sp|P24604|TEC_MOUSE Tyrosine-protein kinase Tec OS=Mus musculus OX=10090 GN=Tec PE=1 SV=2 Length=630 Score = 127 bits (319), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 88/277 (32%), Positives = 134/277 (48%), Gaps = 30/277 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +R+LG G FG V L + VA+KA++ G + +E ++ L H + Sbjct 372 MRELGSGLFGVVRLGKWRAQYK-----VAIKAIRE--GAMCEEDFIEEAKVMMKLTHPKL 424 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQ 1017 ++ G C Q K + +V E++ G L ++L + ++ LL Q +CEGM YL Sbjct 425 VQLYGVCTQQ--KPIYIVTEFMERGCLLNFLRQRQGHFSRDMLLSMCQDVCEGMEYLERN 482 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +IHRDLAARN L++ +VK+ DFG+A+ V + Y PV W PE + Sbjct 483 SFIHRDLAARNCLVNEAGVVKVSDFGMARYVLDDQ--YTSSSGAKFPVKWCPPEVFNYSR 540 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFGV ++E+ T + P K T + ++ RG RL RP Sbjct 541 FSSKSDVWSFGVLMWEIFTE---GRMPFEK-----------NTNYEVVTMVTRGHRLHRP 586 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 +Y +M CW+ RP+ E+L L+T+ E Sbjct 587 KLATKYLYEVMLRCWQERPEGRPSLEDL---LRTIDE 620 Score = 93.2 bits (230), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 60/222 (27%), Positives = 100/222 (45%), Gaps = 16/222 (7%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F E A +M +++H L ++GVC + +VTE++E G L +LR+ +GH + + Sbjct 409 FIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDMLLSM 468 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 Q + + YLE + +H ++ RN L+ G+ +K+SD G+ L + Sbjct 469 CQDVCEGMEYLERNSFIHRDLAARNCLVNEAGV-------VKVSDFGMARYVLDDQYTSS 521 Query 775 R-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 + W PE + S+ D W FG + EI +G P + + E R Sbjct 522 SGAKFPVKWCPPEVF--NYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTR 579 Query 830 QHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 HRL P+ + L + +C P RPS +LR + L Sbjct 580 GHRLHRPKLATKYLYEVMLRCWQERPEGRPSLEDLLRTIDEL 621 >sp|Q19238|YS3J_CAEEL Putative tyrosine-protein kinase F09A5.2 OS=Caenorhabditis elegans OX=6239 GN=F09A5.2 PE=3 SV=3 Length=867 Score = 128 bits (322), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 88/265 (33%), Positives = 130/265 (49%), Gaps = 39/265 (15%) Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVM 978 N+G E A+K L A Q+ + EID ++ L +H H+I GC + E +V+ Sbjct 507 NNGHYE-AAIKKLPAHADEQNHLDFFHEIDFMKRLGHHPHVISMLGCVSNPYEP--LIVV 563 Query 979 EYVPLGSLRDYLPRHS------------------IGLAQLLLFAQQICEGMAYLHAQHYI 1020 EY G L +L RH + + L+ A Q+ +GM+YL ++++I Sbjct 564 EYCARGDLLKFLRRHKDYVLMNKTDDCPIEADMCLRIKDLVSIAWQVADGMSYLASKNFI 623 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARN+LL K+ DFGL + + + G P+ W + E LK Y+F Sbjct 624 HRDLAARNILLTKSLTAKVSDFGLCRYMDSA---LYTAKGGRLPIKWMSVEALKLYEFST 680 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 +DVWSFGV L+E+ + D PT I Q M E L G RL +P KC Sbjct 681 KTDVWSFGVLLFEIFSMGDVPY--PT-------IQQVDM-----LEHLLAGGRLSQPLKC 726 Query 1141 PCEVYHLMKNCWETEASFRPTFENL 1165 P E++++M+ CW + RP F + Sbjct 727 PNEIFNIMQKCWAEKPEDRPEFNEM 751 Score = 78.6 bits (192), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 87/329 (26%), Positives = 141/329 (43%), Gaps = 55/329 (17%) Query 575 NLSQLSFHRVDQKEI-TQLSHL-GQGTRTNVYEGRLRVEGSGDPEEGKM------DDEDP 626 N ++ +D K + Q HL G G NVY+G ++ GK+ + + Sbjct 451 NANKKDIWEIDTKNLLVQEDHLLGNGAFANVYKGIVK---------GKIPLLVVNNSLNM 501 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHT-HLAFVHGVCVRGP-E 682 V + G + K+ P+H D L F+ M ++ H H+ + G CV P E Sbjct 502 TVESENNGHYEAAIKKL--PAHADEQNHLDFFHEIDFMKRLGHHPHVISMLG-CVSNPYE 558 Query 683 NIMVTEYVEHGPLDVWLRRERGHV--------PMAWKMV--------VAQQLASALSYLE 726 ++V EY G L +LRR + +V P+ M +A Q+A +SYL Sbjct 559 PLIVVEYCARGDLLKFLRRHKDYVLMNKTDDCPIEADMCLRIKDLVSIAWQVADGMSYLA 618 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIP--WLAPE 782 +KN +H ++ RNILL + S K+SD G+ + + + R+P W++ E Sbjct 619 SKNFIHRDLAARNILLTK-------SLTAKVSDFGLCRYMDSALYTAKGGRLPIKWMSVE 671 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-Q 840 L ST D W FG L EI G+ P + + RL +P CP + Sbjct 672 ALK--LYEFSTKTDVWSFGVLLFEIFSMGDVPYPTIQQVDMLEHLLAGGRLSQPLKCPNE 729 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + +C +P RP F + ++T + Sbjct 730 IFNIMQKCWAEKPEDRPEFNEMRGEITVM 758 >sp|P54763|EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus musculus OX=10090 GN=Ephb2 PE=1 SV=3 Length=986 Score = 129 bits (323), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 82/273 (30%), Positives = 141/273 (52%), Gaps = 25/273 (9%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G FG+V S + P G E+ VA+K LK+ + R + E I+ H ++I Sbjct 627 IGAGEFGEVCSGHLKLP---GKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVI 683 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018 +G + ++ E++ GSL +L ++ + QL+ + I GM YL + Sbjct 684 HLEGVVTKS--TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMN 741 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076 Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G P+ W APE ++ Sbjct 742 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYR 801 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 KF ASDVWS+G+ ++E++++ + P MT + +E+ RLP Sbjct 802 KFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMTNQDVINAIEQDYRLPP 847 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P CP ++ LM +CW+ + + RP F ++ L Sbjct 848 PMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 880 Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 71/262 (27%), Positives = 125/262 (48%), Gaps = 28/262 (11%) Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 +PG+ +E+ V +K L + + F AS+M Q H ++ + GV + +++ Sbjct 642 LPGK---REIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMII 698 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TE++E+G LD +LR+ G + + + + +A+ + YL + N VH ++ RNIL+ Sbjct 699 TEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNL 758 Query 747 LAE----GTSPFIK--LSDPGV--GLGALSREERVERIP--WLAPECLPGGANSLSTAMD 796 + + G S F++ SDP LG +IP W APE + ++A D Sbjct 759 VCKVSDFGLSRFLEDDTSDPTYTSALGG--------KIPIRWTAPEAIQ--YRKFTSASD 808 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPT 854 W +G + E+ GE P + + + ++ +RLP P CP L L C + Sbjct 809 VWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRN 868 Query 855 QRPSFRTILRDLTRL--QPHNL 874 RP F I+ L ++ P++L Sbjct 869 HRPKFGQIVNTLDKMIRNPNSL 890 >sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens OX=9606 GN=EPHB2 PE=1 SV=5 Length=1055 Score = 129 bits (323), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 82/273 (30%), Positives = 141/273 (52%), Gaps = 25/273 (9%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G FG+V S + P G E+ VA+K LK+ + R + E I+ H ++I Sbjct 627 IGAGEFGEVCSGHLKLP---GKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVI 683 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018 +G + ++ E++ GSL +L ++ + QL+ + I GM YL + Sbjct 684 HLEGVVTKS--TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMN 741 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076 Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G P+ W APE ++ Sbjct 742 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYR 801 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 KF ASDVWS+G+ ++E++++ + P MT + +E+ RLP Sbjct 802 KFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMTNQDVINAIEQDYRLPP 847 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P CP ++ LM +CW+ + + RP F ++ L Sbjct 848 PMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 880 Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 71/262 (27%), Positives = 125/262 (48%), Gaps = 28/262 (11%) Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 +PG+ +E+ V +K L + + F AS+M Q H ++ + GV + +++ Sbjct 642 LPGK---REIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMII 698 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TE++E+G LD +LR+ G + + + + +A+ + YL + N VH ++ RNIL+ Sbjct 699 TEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNL 758 Query 747 LAE----GTSPFIK--LSDPGV--GLGALSREERVERIP--WLAPECLPGGANSLSTAMD 796 + + G S F++ SDP LG +IP W APE + ++A D Sbjct 759 VCKVSDFGLSRFLEDDTSDPTYTSALGG--------KIPIRWTAPEAIQ--YRKFTSASD 808 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPT 854 W +G + E+ GE P + + + ++ +RLP P CP L L C + Sbjct 809 VWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRN 868 Query 855 QRPSFRTILRDLTRL--QPHNL 874 RP F I+ L ++ P++L Sbjct 869 HRPKFGQIVNTLDKMIRNPNSL 890 >sp|P55146|TYRO3_RAT Tyrosine-protein kinase receptor TYRO3 OS=Rattus norvegicus OX=10116 GN=Tyro3 PE=1 SV=1 Length=880 Score = 128 bits (322), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 95/277 (34%), Positives = 132/277 (48%), Gaps = 28/277 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHI 959 R LG+G FG V DG+ VAVK LKAD + +E ++ H H+ Sbjct 512 RMLGKGEFGSVREAQLK-QEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHV 570 Query 960 IKYKGCC-EDQGEKSLQLVMEYVPL---GSLRDYLPRHSIG-------LAQLLLFAQQIC 1008 K G + + L + M +P G L +L IG L L+ F I Sbjct 571 AKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLVRFMVDIA 630 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 GM YL ++++IHRDLAARN +L D V + DFGL++ + G +YYR PV W Sbjct 631 CGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSG-DYYRQGCASKLPVKWL 689 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A E L + + SDVW+FGVT++E++T Q+P GI + + L Sbjct 690 ALESLADNLYTVHSDVWAFGVTMWEIMTR---GQTP------YAGIENAE-----IYNYL 735 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 G RL +P +C EVY LM CW + RP+F L Sbjct 736 ISGNRLKQPPECMEEVYDLMYQCWSADPKQRPSFTCL 772 Score = 78.2 bits (191), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 92/359 (26%), Positives = 159/359 (44%), Gaps = 60/359 (17%) Query 606 GRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP---SHHDIALAFYETASL 661 GR+ +G G E ++ ED G ++V +K+L + DI F A+ Sbjct 511 GRMLGKGEFGSVREAQLKQED--------GSFVKVAVKMLKADIIASSDIE-EFLREAAC 561 Query 662 MSQVSHTHLAFVHGVCVRG------PENIMVTEYVEHGPLDVWLRRER-----GHVPMAW 710 M + H H+A + GV +R P +++ +++HG L +L R ++P+ Sbjct 562 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQT 621 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGA 766 + +A + YL ++N +H ++ RN +LA + ++D G+ G Sbjct 622 LVRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE-------DMTVCVADFGLSRKIYSGD 674 Query 767 LSREERVERIP--WLAPECLPGGANSLSTA-MDKWGFGATLLEICFDGEAPLQSRSPSEK 823 R+ ++P WLA E L A++L T D W FG T+ EI G+ P +E Sbjct 675 YYRQGCASKLPVKWLALESL---ADNLYTVHSDVWAFGVTMWEIMTRGQTPYAGIENAEI 731 Query 824 EHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 ++ +RL +P ++ L QC + +P QRPSF + R++ N+ L+V Sbjct 732 YNYLISGNRLKQPPECMEEVYDLMYQCWSADPKQRPSFTCL-----RMELENILGHLSVL 786 Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN----DGTGEMVAVKALKADC 936 S + DP Y+ R G L C + ++ DG+G M A+ + +DC Sbjct 787 --STSQDPL-----YINIERAGQPAENGSPELPCGEQSSSEAGDGSG-MGAIGGIPSDC 837 >sp|Q13882|PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo sapiens OX=9606 GN=PTK6 PE=1 SV=1 Length=451 Score = 124 bits (312), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 89/268 (33%), Positives = 135/268 (50%), Gaps = 28/268 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LG G+FG+V + VA+K + D H+ + EI ++ L H+HI+ Sbjct 195 RKLGSGYFGEVFEGLWKDRVQ-----VAIKVISRD-NLLHQQMLQSEIQAMKKLRHKHIL 248 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + ++ E + GSL + L + +++LL A Q+ EGM YL +Q Sbjct 249 ALYAVV--SVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQ 306 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +YIHRDLAARN+L+ + L K+GDFGLA+ + E + D + P W APE L Sbjct 307 NYIHRDLAARNILVGENTLCKVGDFGLARLIKED---VYLSHDHNIPYKWTAPEALSRGH 363 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + SDVWSFG+ L+E+ + Q P G++ + LR ++ G R+P P Sbjct 364 YSTKSDVWSFGILLHEMFSR---GQVP------YPGMSNHE-AFLR----VDAGYRMPCP 409 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165 +CP V+ LM CW + RP F+ L Sbjct 410 LECPPSVHKLMLTCWCRDPEQRPCFKAL 437 Score = 78.2 bits (191), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 65/220 (30%), Positives = 99/220 (45%), Gaps = 20/220 (9%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV-PMAWKMVVAQQLAS 720 M ++ H H+ ++ V G ++TE + G L LR V P++ + +A Q+A Sbjct 239 MKKLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAE 298 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV----ERI 776 + YLE++N +H ++ RNIL+ G + K+ D GL L +E+ I Sbjct 299 GMCYLESQNYIHRDLAARNILV-------GENTLCKVGD--FGLARLIKEDVYLSHDHNI 349 Query 777 P--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834 P W APE L G ST D W FG L E+ G+ P S E +R+P Sbjct 350 PYKWTAPEALSRG--HYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMP 407 Query 835 EP-SC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 P C P + L C +P QRP F+ + L+ + Sbjct 408 CPLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFTSY 447 >sp|P28693|EPHB2_CHICK Ephrin type-B receptor 2 OS=Gallus gallus OX=9031 GN=EPHB2 PE=1 SV=3 Length=1004 Score = 128 bits (321), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 82/273 (30%), Positives = 141/273 (52%), Gaps = 25/273 (9%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G FG+V S + P G E+ VA+K LK+ + R + E I+ H ++I Sbjct 645 IGAGEFGEVCSGHLKLP---GKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVI 701 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018 +G + ++ E++ GSL +L ++ + QL+ + I GM YL + Sbjct 702 HLEGVVTK--SSPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMN 759 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076 Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G P+ W APE ++ Sbjct 760 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYR 819 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 KF ASDVWS+G+ ++E++++ + P MT + +E+ RLP Sbjct 820 KFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMTNQDVINAIEQDYRLPP 865 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P CP ++ LM +CW+ + + RP F ++ L Sbjct 866 PMDCPNALHQLMLDCWQKDRNHRPKFGQIVNTL 898 Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 71/262 (27%), Positives = 125/262 (48%), Gaps = 28/262 (11%) Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 +PG+ +E+ V +K L + + F AS+M Q H ++ + GV + +++ Sbjct 660 LPGK---REIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMII 716 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TE++E+G LD +LR+ G + + + + +A+ + YL + N VH ++ RNIL+ Sbjct 717 TEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNL 776 Query 747 LAE----GTSPFIK--LSDPGV--GLGALSREERVERIP--WLAPECLPGGANSLSTAMD 796 + + G S F++ SDP LG +IP W APE + ++A D Sbjct 777 VCKVSDFGLSRFLEDDTSDPTYTSALGG--------KIPIRWTAPEAIQ--YRKFTSASD 826 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPT 854 W +G + E+ GE P + + + ++ +RLP P CP L L C + Sbjct 827 VWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPNALHQLMLDCWQKDRN 886 Query 855 QRPSFRTILRDLTRL--QPHNL 874 RP F I+ L ++ P++L Sbjct 887 HRPKFGQIVNTLDKMIRNPNSL 908 >sp|P29376|LTK_HUMAN Leukocyte tyrosine kinase receptor OS=Homo sapiens OX=9606 GN=LTK PE=1 SV=3 Length=864 Score = 127 bits (320), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 94/300 (31%), Positives = 140/300 (47%), Gaps = 38/300 (13%) Query 900 IRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +R LG G FG+V L P D + VA+K L C PQ + E I+ H+ Sbjct 513 LRALGHGAFGEVYEGLVIGLP-GDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQ 571 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------IGLAQLLLFAQQIC 1008 +I++ G + +++E + G ++ +L RHS + + LL AQ I Sbjct 572 NIVRCVGLSLRATPR--LILLELMSGGDMKSFL-RHSRPHLGQPSPLVMRDLLQLAQDIA 628 Query 1009 EGMAYLHAQHYIHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 +G YL H+IHRD+AARN LL R+ KIGDFG+A+ + YYR + PV Sbjct 629 QGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRA-SYYRRGDRALLPV 687 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 W PE E F +D WSFGV L+E+ + ++ G T + Sbjct 688 KWMPPEAFLEGIFTSKTDSWSFGVLLWEIFS---------LGYMPYPG-----RTNQEVL 733 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 + + G R+ P CP VY +M CW+ E RP+F +++ L +Y Q P V + Sbjct 734 DFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERL-----QYCTQDPDVLN 788 Score = 80.9 bits (198), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 83/299 (28%), Positives = 124/299 (41%), Gaps = 42/299 (14%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +T L LG G VYEG + G D PL +V +K Sbjct 505 VSPANVTLLRALGHGAFGEVYEGLVI---------GLPGDSSPL----------QVAIKT 545 Query 644 LDP--SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 L S D L F A ++S+ H ++ G+ +R +++ E + G + +LR Sbjct 546 LPELCSPQD-ELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRH 604 Query 702 ERGHVPMAWKMV------VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 R H+ +V +AQ +A YLE + +H ++ RN LL+ G S Sbjct 605 SRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLS----CAGPSRVA 660 Query 756 KLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 K+ D G+ + S R +R + W+ PE G ++ D W FG L EI Sbjct 661 KIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGI--FTSKTDSWSFGVLLWEIFS 718 Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDL 866 G P R+ E F R+ P CP + + +QC +EP RPSF +IL L Sbjct 719 LGYMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERL 777 >sp|Q8JH64|BTK_CHICK Tyrosine-protein kinase BTK OS=Gallus gallus OX=9031 GN=BTK PE=1 SV=1 Length=657 Score = 126 bits (317), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 83/269 (31%), Positives = 133/269 (49%), Gaps = 27/269 (10%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +++LG G FG V + + VA+K ++ G + E ++ L HE + Sbjct 403 LKELGTGQFGVVKYGKWRGQYN-----VAIKMIRE--GSMSEDEFIDEAKVMMNLSHEKL 455 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 ++ G C Q + + ++ EY+ G L ++L + A+LL + +CE M YL ++ Sbjct 456 VQLYGVCTKQ--RPIFIITEYMANGCLLNFLRETQRRFQPAELLEMCKDVCEAMEYLESK 513 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 ++HRDLAARN L+++ +VK+ DFGL++ V + Y PV W PE L K Sbjct 514 QFLHRDLAARNCLVNDQGIVKVSDFGLSRYVLDDE--YTSSMGSKFPVRWSPPEVLLYSK 571 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFGV ++E+ + L + + TE + +G RL RP Sbjct 572 FSSKSDVWSFGVLMWEVYS--------------LGKMPYERFNNSETTEHVIQGLRLYRP 617 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + VY +M +CW +A RPTF L+ Sbjct 618 QQASERVYAIMYSCWHEKAEERPTFSALL 646 Score = 79.7 bits (195), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 79/323 (24%), Positives = 140/323 (43%), Gaps = 54/323 (17%) Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE---EG 619 + R +++P T L S+ +D K++T L LG G V G+ R + + + EG Sbjct 375 VSRHQKSAPSTAGLGYGSWE-IDPKDLTFLKELGTGQFGVVKYGKWRGQYNVAIKMIREG 433 Query 620 KMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR 679 M +++ F + A +M +SH L ++GVC + Sbjct 434 SMSEDE-----------------------------FIDEAKVMMNLSHEKLVQLYGVCTK 464 Query 680 GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRN 739 ++TEY+ +G L +LR + A + + + + A+ YLE+K +H ++ RN Sbjct 465 QRPIFIITEYMANGCLLNFLRETQRRFQPAELLEMCKDVCEAMEYLESKQFLHRDLAARN 524 Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTA 794 L+ G+ +K+SD G+ L E + W PE L + S+ Sbjct 525 CLVNDQGI-------VKVSDFGLSRYVLDDEYTSSMGSKFPVRWSPPEVLL--YSKFSSK 575 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSE-KEHFYQ--RQHRLPEPSCPQLATLTSQCLTY 851 D W FG + E+ G+ P + + SE EH Q R +R P+ + ++ + C Sbjct 576 SDVWSFGVLMWEVYSLGKMPYERFNNSETTEHVIQGLRLYR-PQQASERVYAIMYSCWHE 634 Query 852 EPTQRPSFRTIL---RDLTRLQP 871 + +RP+F +L D+T +P Sbjct 635 KAEERPTFSALLGSIVDITDEEP 657 >sp|Q62413|EPHA6_MOUSE Ephrin type-A receptor 6 OS=Mus musculus OX=10090 GN=Epha6 PE=1 SV=2 Length=1035 Score = 128 bits (321), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 94/342 (27%), Positives = 158/342 (46%), Gaps = 70/342 (20%) Query 880 VNPDSPASDPTVFHKRYLKKI--------RDLGEGHFGKVSLYCYDPTND-GTGEM-VAV 929 ++PD+ DP++ + K+I R +G G FG+V C G E+ VA+ Sbjct 606 IDPDT-YEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEV---CSGRLKTPGKREIPVAI 661 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ-------------------- 969 K LK + R + +E I+ H +II+ +G + Sbjct 662 KTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFL 721 Query 970 --------------------GEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQI 1007 + + +V+EY+ GSL +L +H + QL+ + I Sbjct 722 NGIQAPHPVTAGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGI 781 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 GM YL Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W Sbjct 782 ASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRW 841 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + KF ASD WS+G+ ++E++++ + P + E+ Q +L Sbjct 842 TAPEAIAYRKFSSASDAWSYGIVMWEVMSY---GERP---YWEM----SNQDVILS---- 887 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 +E G RLP P CP ++ LM +CW+ E + RP F +++ L Sbjct 888 IEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFL 929 Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 87/341 (26%), Positives = 134/341 (39%), Gaps = 70/341 (21%) Query 607 RLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQ 664 R+R+E G E G++ PG+ +E+ V +K L H D F AS+M Q Sbjct 629 RIRIERVIGAGEFGEVCSGRLKTPGK---REIPVAIKTLKGGHMDRQRRDFLREASIMGQ 685 Query 665 VSHTHLAFVHGVCVR------------------------------------------GPE 682 H ++ + GV + G Sbjct 686 FDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNGIQAPHPVTAGGSLPPRIPAGRP 745 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 ++V EY+E+G LD +LR+ GH + + + + +AS + YL + VH ++ RNIL+ Sbjct 746 VMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILV 805 Query 743 ARLGLAEGTSPFIKLSDPGVGL-------GALSREERVERIPWLAPECLPGGANSLSTAM 795 ++ K+SD G+ A + I W APE + S+A Sbjct 806 -------NSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAI--AYRKFSSAS 856 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC-PQLATLTSQCLTYEP 853 D W +G + E+ GE P S + + +RLP P C P L L C E Sbjct 857 DAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKER 916 Query 854 TQRPSFRTILRDLTRL-----QPHNLADVLTVNPDSPASDP 889 RP F I+ L +L H L + + V P+SP P Sbjct 917 NHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGDVP 957 >sp|P55144|TYRO3_MOUSE Tyrosine-protein kinase receptor TYRO3 OS=Mus musculus OX=10090 GN=Tyro3 PE=1 SV=2 Length=880 Score = 127 bits (319), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 95/277 (34%), Positives = 132/277 (48%), Gaps = 28/277 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHI 959 R LG+G FG V DG+ VAVK LKAD + +E ++ H H+ Sbjct 512 RMLGKGEFGSVREAQLK-QEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHV 570 Query 960 IKYKGCC-EDQGEKSLQLVMEYVPL---GSLRDYLPRHSIG-------LAQLLLFAQQIC 1008 K G + + L + M +P G L +L IG L L+ F I Sbjct 571 AKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLVRFMVDIA 630 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 GM YL ++++IHRDLAARN +L D V + DFGL++ + G +YYR PV W Sbjct 631 CGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSG-DYYRQGCASKLPVKWL 689 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A E L + + SDVW+FGVT++E++T Q+P GI + + L Sbjct 690 ALESLADNLYTVHSDVWAFGVTMWEIMTR---GQTP------YAGIENAE-----IYNYL 735 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 G RL +P +C EVY LM CW + RP+F L Sbjct 736 IGGNRLKQPPECMEEVYDLMYQCWSADPKQRPSFTCL 772 Score = 74.7 bits (182), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 78/302 (26%), Positives = 136/302 (45%), Gaps = 45/302 (15%) Query 606 GRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP---SHHDIALAFYETASL 661 GR+ +G G E ++ ED G ++V +K+L + DI F A+ Sbjct 511 GRMLGKGEFGSVREAQLKQED--------GSFVKVAVKMLKADIIASSDIE-EFLREAAC 561 Query 662 MSQVSHTHLAFVHGVCVRG------PENIMVTEYVEHGPLDVWLRRER-----GHVPMAW 710 M + H H+A + GV +R P +++ +++HG L +L R ++P+ Sbjct 562 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQT 621 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGA 766 + +A + YL ++N +H ++ RN +LA + ++D G+ G Sbjct 622 LVRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE-------DMTVCVADFGLSRKIYSGD 674 Query 767 LSREERVERIP--WLAPECLPGGANSLSTA-MDKWGFGATLLEICFDGEAPLQSRSPSEK 823 R+ ++P WLA E L A++L T D W FG T+ EI G+ P +E Sbjct 675 YYRQGCASKLPVKWLALESL---ADNLYTVHSDVWAFGVTMWEIMTRGQTPYAGIENAEI 731 Query 824 EHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 ++ +RL +P ++ L QC + +P QRPSF + +L + H VL+ + Sbjct 732 YNYLIGGNRLKQPPECMEEVYDLMYQCWSADPKQRPSFTCLRMELENILGH--LSVLSTS 789 Query 882 PD 883 D Sbjct 790 QD 791 >sp|D2IYS2|TORSO_BOMMO Tyrosine-protein kinase receptor torso OS=Bombyx mori OX=7091 GN=tor PE=1 SV=1 Length=807 Score = 127 bits (319), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 93/312 (30%), Positives = 138/312 (44%), Gaps = 71/312 (23%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961 +GEG FG V P G+ VAVK LK + ++ E+++++++ H H++ Sbjct 445 IGEGAFGVVRRGTLAPG----GKSVAVKMLKEFPSQEEVRSFRSEMELMKSVGAHPHVVS 500 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--------PRHSIGLAQ-------------- 999 GCC G K L +V EY G L YL +H+ Sbjct 501 LVGCC--SGRKPL-IVAEYCSRGDLLSYLRSSWDIIVSKHTAKYYNNNMDSMDTSKLKVH 557 Query 1000 --------------------------LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033 LL F +QI GM +L + +HRDLAARNVL+ Sbjct 558 KEHTKLVVNKLYELQGPCETELTPLDLLSFCRQIAMGMEFLASNRIVHRDLAARNVLVTE 617 Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 D+ +KI DFGL++ + E ++ Y+ + +G PV W A E L + SDVWSFGV ++E Sbjct 618 DKTLKIADFGLSRDIYEENQ-YKQKGNGKMPVKWMALESLTRRVYTTQSDVWSFGVVIWE 676 Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 ++T + G ++ RL L G R+P+P C +Y +M+ CW Sbjct 677 IVT--------------VGGSPYPEVPAARLVRSLRSGYRMPKPVNCSKPLYDIMRACWN 722 Query 1154 TEASFRPTFENL 1165 RPTF L Sbjct 723 ASPRDRPTFPEL 734 Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 46/196 (23%), Positives = 82/196 (42%), Gaps = 22/196 (11%) Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER 775 +Q+A + +L + +VH ++ RN+L+ +K++D G+ + ++ Sbjct 589 RQIAMGMEFLASNRIVHRDLAARNVLVTE-------DKTLKIADFGLSRDIYEENQYKQK 641 Query 776 ------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 + W+A E L +T D W FG + EI G +P + + Sbjct 642 GNGKMPVKWMALESL--TRRVYTTQSDVWSFGVVIWEIVTVGGSPYPEVPAARLVRSLRS 699 Query 830 QHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI---LRDLTRLQPHNLADVLTVNPDS 884 +R+P+P +C + L + C P RP+F + L DL N L V+ D Sbjct 700 GYRMPKPVNCSKPLYDIMRACWNASPRDRPTFPELHQKLDDLLHSACANEYITLEVDVDE 759 Query 885 PASDPTVFHKRYLKKI 900 S P +RY+K + Sbjct 760 APSTPK--PQRYIKML 773 >sp|P16879|FES_MOUSE Tyrosine-protein kinase Fes/Fps OS=Mus musculus OX=10090 GN=Fes PE=1 SV=2 Length=822 Score = 127 bits (318), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 87/277 (31%), Positives = 137/277 (49%), Gaps = 23/277 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G+FG+V + D T VAVK+ + P ++ + QE IL+ H +I++ Sbjct 567 IGRGNFGEV--FSGRLRADNTP--VAVKSCRETLPPDLKAKFLQEARILKQYNHPNIVRL 622 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C + + + +VME V G +L + + LL GM YL ++ I Sbjct 623 IGVCTQK--QPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCI 680 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARN L+ ++KI DFG+++ +G Y PV W APE L ++ Sbjct 681 HRDLAARNCLVTEKNVLKISDFGMSREEADGI-YAASAGLRQVPVKWTAPEALNYGRYSS 739 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWSFG+ L+E + +S P +T + E +E+G RLP P+ C Sbjct 740 ESDVWSFGILLWETFS-LGASPYP-------------NLTNQQTREFVEKGHRLPCPELC 785 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 P V+ LM+ CW E RP+F + L ++ ++++ Sbjct 786 PDAVFRLMEQCWAYEPGQRPSFSIICQELHSIRKRHR 822 Score = 98.6 bits (244), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 79/281 (28%), Positives = 125/281 (44%), Gaps = 40/281 (14%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 +G+G V+ GRLR D P+ ++ + L P D+ Sbjct 566 QIGRGNFGEVFSGRLRA------------DNTPVA--------VKSCRETLPP---DLKA 602 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F + A ++ Q +H ++ + GVC + +V E V+ G +LR E + + + Sbjct 603 KFLQEARILKQYNHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQ 662 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGAL 767 + A+ + YLE+K +H ++ RN L+ + +K+SD G+ G+ A Sbjct 663 MVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNV-------LKISDFGMSREEADGIYAA 715 Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 S R + W APE L G S+ D W FG L E G +P + + + F Sbjct 716 SAGLRQVPVKWTAPEALNYG--RYSSESDVWSFGILLWETFSLGASPYPNLTNQQTREFV 773 Query 828 QRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866 ++ HRLP P CP + L QC YEP QRPSF I ++L Sbjct 774 EKGHRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSIICQEL 814 >sp|P08941|ROS1_CHICK Proto-oncogene tyrosine-protein kinase ROS OS=Gallus gallus OX=9031 GN=ROS1 PE=1 SV=3 Length=2311 Score = 128 bits (321), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 96/278 (35%), Positives = 134/278 (48%), Gaps = 37/278 (13%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG G FG+V D DG+GE VAVK LK Q +S + +E ++ H HI+ Sbjct 1967 LGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMSKFDHPHIL 2026 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQLLLFAQQICEG 1010 K G C + L++E + G L YL P ++ + IC+G Sbjct 2027 KLLGVCLLNEPQ--YLILELMEGGDLLSYLRGARKQKFQSPLLTLTDLLDICL--DICKG 2082 Query 1011 MAYLHAQHYIHRDLAARNVLLDN------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 YL +IHRDLAARN L+ R+VKIGDFGLA+ + + ++YYR R +G Sbjct 2083 CVYLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYK-NDYYRKRGEGLIN 2141 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 V W APE L + F SDVW+FGV ++E LT Q P ++ + + Sbjct 2142 VRWMAPESLIDGVFTNHSDVWAFGVLVWETLTL---GQQP-----------YPGLSNIEV 2187 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 + G RL P+ CP ++ LM CW + RPTF Sbjct 2188 LHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTF 2225 Score = 73.6 bits (179), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 75/294 (26%), Positives = 116/294 (39%), Gaps = 42/294 (14%) Query 595 LGQGTRTNVYEGR---LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651 LG G VYEG + +GSG E RV +K L D Sbjct 1967 LGSGAFGEVYEGTALDILADGSG---------------------ESRVAVKTLKRGATDQ 2005 Query 652 ALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH----- 705 + F + A LMS+ H H+ + GVC+ ++ E +E G L +LR R Sbjct 2006 EKSEFLKEAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRGARKQKFQSP 2065 Query 706 -VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + + + + YLE +H ++ RN L++ S +K+ D G+ Sbjct 2066 LLTLTDLLDICLDICKGCVYLEKMRFIHRDLAARNCLVSEKQYG-SCSRVVKIGDFGLAR 2124 Query 765 GAL------SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 R E + + W+APE L G + D W FG + E G+ P Sbjct 2125 DIYKNDYYRKRGEGLINVRWMAPESLIDGV--FTNHSDVWAFGVLVWETLTLGQQPYPGL 2182 Query 819 SPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 S E H + RL P +CP + L ++C +P RP+F I L ++ Sbjct 2183 SNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEIR 2236 >sp|Q06418|TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3 OS=Homo sapiens OX=9606 GN=TYRO3 PE=1 SV=1 Length=890 Score = 127 bits (319), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 94/277 (34%), Positives = 132/277 (48%), Gaps = 28/277 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHI 959 R LG+G FG V DG+ VAVK LKAD + +E ++ H H+ Sbjct 522 RMLGKGEFGSVREAQLK-QEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHV 580 Query 960 IKYKGCC-EDQGEKSLQLVMEYVPL---GSLRDYLPRHSIG-------LAQLLLFAQQIC 1008 K G + + L + M +P G L +L IG L L+ F I Sbjct 581 AKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLIRFMVDIA 640 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 GM YL ++++IHRDLAARN +L D V + DFGL++ + G +YYR PV W Sbjct 641 CGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSG-DYYRQGCASKLPVKWL 699 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 A E L + + SDVW+FGVT++E++T Q+P GI + + L Sbjct 700 ALESLADNLYTVQSDVWAFGVTMWEIMTR---GQTP------YAGIENAE-----IYNYL 745 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 G RL +P +C +VY LM CW + RP+F L Sbjct 746 IGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCL 782 Score = 76.6 bits (187), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 91/357 (25%), Positives = 153/357 (43%), Gaps = 56/357 (16%) Query 606 GRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP---SHHDIALAFYETASL 661 GR+ +G G E ++ ED G ++V +K+L + DI F A+ Sbjct 521 GRMLGKGEFGSVREAQLKQED--------GSFVKVAVKMLKADIIASSDIE-EFLREAAC 571 Query 662 MSQVSHTHLAFVHGVCVRG------PENIMVTEYVEHGPLDVWLRRER-----GHVPMAW 710 M + H H+A + GV +R P +++ +++HG L +L R ++P+ Sbjct 572 MKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQT 631 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGA 766 + +A + YL ++N +H ++ RN +LA + ++D G+ G Sbjct 632 LIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE-------DMTVCVADFGLSRKIYSGD 684 Query 767 LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 R+ ++P WLA E L N + D W FG T+ EI G+ P +E Sbjct 685 YYRQGCASKLPVKWLALESL--ADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIY 742 Query 825 HFYQRQHRLPE-PSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 ++ +RL + P C + + L QC + +P QRPSF + R++ N+ L+V Sbjct 743 NYLIGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCL-----RMELENILGQLSVL- 796 Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE---MVAVKALKADC 936 S + DP Y+ R G + L D G G+ M AV +DC Sbjct 797 -SASQDPL-----YINIERAEEPTAGGSLELPGRDQPYSGAGDGSGMGAVGGTPSDC 847 >sp|Q90344|EPHB2_COTJA Ephrin type-B receptor 2 OS=Coturnix japonica OX=93934 GN=EPHB2 PE=2 SV=1 Length=987 Score = 127 bits (319), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 82/273 (30%), Positives = 140/273 (51%), Gaps = 25/273 (9%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G FG+V S + P G E+ VA+K LK+ + R + E I+ H ++I Sbjct 628 IGAGEFGEVCSGHLKLP---GKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVI 684 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018 +G + ++ E++ GSL +L ++ + QL+ + I GM YL + Sbjct 685 HLEGVVTK--SSPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMN 742 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076 Y+HRDLAARN L++++ + K+ DFGL++ + + Y G P+ W APE ++ Sbjct 743 YVHRDLAARNTLVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYR 802 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 KF ASDVWS+G+ ++E++++ + P MT + +E+ RLP Sbjct 803 KFTSASDVWSYGIVMWEVMSY---GERP-----------YWDMTNQDVINAIEQDYRLPP 848 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P CP ++ LM +CW+ + + RP F ++ L Sbjct 849 PMDCPNALHQLMLDCWQKDRNHRPKFGQIVNTL 881 Score = 87.0 bits (214), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 70/262 (27%), Positives = 124/262 (47%), Gaps = 28/262 (11%) Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 +PG+ +E+ V +K L + + F AS+M Q H ++ + GV + +++ Sbjct 643 LPGK---REIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMII 699 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TE++E+G LD +LR+ G + + + + +A+ + YL + N VH ++ RN L+ Sbjct 700 TEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNTLVNSNL 759 Query 747 LAE----GTSPFIK--LSDPGV--GLGALSREERVERIP--WLAPECLPGGANSLSTAMD 796 + + G S F++ SDP LG +IP W APE + ++A D Sbjct 760 VCKVSDFGLSRFLEDDTSDPTYTSALGG--------KIPIRWTAPEAIQ--YRKFTSASD 809 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPT 854 W +G + E+ GE P + + + ++ +RLP P CP L L C + Sbjct 810 VWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPNALHQLMLDCWQKDRN 869 Query 855 QRPSFRTILRDLTRL--QPHNL 874 RP F I+ L ++ P++L Sbjct 870 HRPKFGQIVNTLDKMIRNPNSL 891 >sp|Q54TM7|DRKD_DICDI Probable serine/threonine-protein kinase drkD OS=Dictyostelium discoideum OX=44689 GN=drkD PE=2 SV=1 Length=1288 Score = 127 bits (319), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 96/285 (34%), Positives = 144/285 (51%), Gaps = 39/285 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G +G+V + G VAVK L D + S ++E+D+L L H +I+ Sbjct 857 IGRGGYGQVFRGSW------RGTEVAVKMLFNDNVNLKLISDLRKEVDLLCKLRHPNIVL 910 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI----GLAQLLLFAQQICEGMAYLHAQ 1017 + G C + S +V EY+ GSL + L SI GL L F GM YLH++ Sbjct 911 FMGACTEPS--SPCIVTEYLSRGSLANILLDESIEMDWGLRLQLGF--DCARGMTYLHSR 966 Query 1018 H--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + IHRDL N+L+D+ VK+ DFGLA + H + + W APE L E Sbjct 967 NPIIIHRDLKTDNLLVDDSWQVKVADFGLATV--KSHTFAKTM---CGTTGWVAPEVLAE 1021 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA-QGQMTVLRLTELLERGERL 1134 + +DV+S+ + L+ELLT LI A + M V+R ++RGERL Sbjct 1022 EGYTEKADVYSYAIVLWELLTR-------------LIPYAGKNTMQVVRS---IDRGERL 1065 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 P P CP + LM CWET+ + RP+F ++PI++ + ++Q + Sbjct 1066 PMPAWCPPKYAALMNRCWETDPTHRPSFPEILPIMEGMISEFQKE 1110 Score = 55.1 bits (131), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 56/239 (23%), Positives = 101/239 (42%), Gaps = 20/239 (8%) Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 RG E+ V + D + + + L+ ++ H ++ G C +VTEY+ Sbjct 871 RGTEVAVKMLFNDNVNLKLISDLRKEVDLLCKLRHPNIVLFMGACTEPSSPCIVTEYLSR 930 Query 693 GPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEG 750 G L L E + ++ + A ++YL ++N ++H ++ N+L+ Sbjct 931 GSLANILLDESIEMDWGLRLQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLV-------D 983 Query 751 TSPFIKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLE 806 S +K++D GL + + + W+APE L + D + + L E Sbjct 984 DSWQVKVAD--FGLATVKSHTFAKTMCGTTGWVAPEVL--AEEGYTEKADVYSYAIVLWE 1039 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-C-PQLATLTSQCLTYEPTQRPSFRTIL 863 + P ++ + R RLP P+ C P+ A L ++C +PT RPSF IL Sbjct 1040 L-LTRLIPYAGKNTMQVVRSIDRGERLPMPAWCPPKYAALMNRCWETDPTHRPSFPEIL 1097 >sp|Q8QFP9|TYRO3_XENLA Tyrosine-protein kinase receptor TYRO3 OS=Xenopus laevis OX=8355 GN=tyro3 PE=1 SV=1 Length=880 Score = 126 bits (317), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 93/285 (33%), Positives = 136/285 (48%), Gaps = 30/285 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEH 958 R LG+G FG V D T + VAVK LKA+ C + +E ++ H + Sbjct 507 RTLGKGEFGSVR-EAQLKMEDDTMQKVAVKMLKAEIFCSSDIEE-FLREAAFMKEFDHPN 564 Query 959 IIKYKGCCEDQGEKSL----QLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFAQQI 1007 + K G K +++ ++ G L +L IG + L+ F I Sbjct 565 VCKLIGVSLRSRTKGRLPVPMVILPFMKHGDLHTFLLMSRIGEEPITLPVQTLVRFMIDI 624 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 C GM YL ++++IHRDLA RN +L+ D V + DFGL+K + G +YYR PV W Sbjct 625 CSGMEYLSSKNFIHRDLATRNCMLNEDMTVCVADFGLSKKIYSG-DYYRQGCASKLPVKW 683 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 A E L + + SDVW+FGVTL+E+ T Q+P G+ + + Sbjct 684 LALESLADNVYTVHSDVWAFGVTLWEIATL---GQTP------YAGVENSE-----IYSY 729 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 L G RL +P C E+Y +M CW TE RP+F +L L+ + Sbjct 730 LIAGNRLKQPLDCLDELYEMMCQCWITEPKRRPSFVDLKQRLEAI 774 Score = 70.1 bits (170), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 79/303 (26%), Positives = 128/303 (42%), Gaps = 49/303 (16%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S+L + Q++ T LG+G +V E +L KM+D D Q+ Sbjct 491 SKLKDVLIQQQQFTLGRTLGKGEFGSVREAQL-----------KMED--------DTMQK 531 Query 637 LRV-VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEY 689 + V +LK DI F A+ M + H ++ + GV +R P +++ + Sbjct 532 VAVKMLKAEIFCSSDIE-EFLREAAFMKEFDHPNVCKLIGVSLRSRTKGRLPVPMVILPF 590 Query 690 VEHGPLDVWLRRER-GHVPMAWKMVVAQQ----LASALSYLENKNLVHGNVCGRNILLAR 744 ++HG L +L R G P+ + + + S + YL +KN +H ++ RN +L Sbjct 591 MKHGDLHTFLLMSRIGEEPITLPVQTLVRFMIDICSGMEYLSSKNFIHRDLATRNCMLNE 650 Query 745 LGLAEGTSPFIKLSDPGVGL----GALSREERVERIP--WLAPECLPGGANSLSTAMDKW 798 + ++D G+ G R+ ++P WLA E L N + D W Sbjct 651 -------DMTVCVADFGLSKKIYSGDYYRQGCASKLPVKWLALESL--ADNVYTVHSDVW 701 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQR 856 FG TL EI G+ P SE + +RL +P +L + QC EP +R Sbjct 702 AFGVTLWEIATLGQTPYAGVENSEIYSYLIAGNRLKQPLDCLDELYEMMCQCWITEPKRR 761 Query 857 PSF 859 PSF Sbjct 762 PSF 764 >sp|Q03526|ITK_MOUSE Tyrosine-protein kinase ITK/TSK OS=Mus musculus OX=10090 GN=Itk PE=1 SV=1 Length=625 Score = 125 bits (313), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 83/280 (30%), Positives = 131/280 (47%), Gaps = 27/280 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L ++++G G FG V L + + VA+K ++ G + +E +++ L H Sbjct 368 LTFVQEIGSGQFGLVHLGYW-----LNKDKVAIKTIQE--GAMSEEDFIEEAEVMMKLSH 420 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYL 1014 +++ G C +Q + LV E++ G L DYL R LL +CEGMAYL Sbjct 421 PKLVQLYGVCLEQA--PICLVFEFMEHGCLSDYLRSQRGLFAAETLLGMCLDVCEGMAYL 478 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDLAARN L+ ++++K+ DFG+ + V + Y PV W +PE Sbjct 479 EKACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQ--YTSSTGTKFPVKWASPEVFS 536 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 ++ SDVWSFGV ++E+ + I + + E + G RL Sbjct 537 FSRYSSKSDVWSFGVLMWEVFSEGK--------------IPYENRSNSEVVEDISTGFRL 582 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 +P C VY +M +CW+ + RP F L+ L + E Sbjct 583 YKPRLASCHVYQIMNHCWKEKPEDRPPFSQLLSQLAEIAE 622 Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 61/223 (27%), Positives = 103/223 (46%), Gaps = 18/223 (8%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F E A +M ++SH L ++GVC+ +V E++EHG L +LR +RG + + Sbjct 408 FIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRSQRGLFAAETLLGM 467 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + ++YLE ++H ++ RN L+ G + IK+SD G+ L + Sbjct 468 CLDVCEGMAYLEKACVIHRDLAARNCLV-------GENQVIKVSDFGMTRFVLDDQYTSS 520 Query 775 R-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 + W +PE + S+ D W FG + E+ +G+ P ++RS SE Sbjct 521 TGTKFPVKWASPEVF--SFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDIST 578 Query 830 QHRLPEP---SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 RL +P SC + + + C +P RP F +L L + Sbjct 579 GFRLYKPRLASC-HVYQIMNHCWKEKPEDRPPFSQLLSQLAEI 620 >sp|P18475|TORSO_DROME Tyrosine-protein kinase receptor torso OS=Drosophila melanogaster OX=7227 GN=tor PE=1 SV=2 Length=923 Score = 126 bits (317), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 73/187 (39%), Positives = 98/187 (52%), Gaps = 14/187 (7%) Query 979 EYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 EY D PR + A LL AQQ+ GM +L +HRDLAARNVL+ DR +K Sbjct 697 EYFDCLDSSDTKPRIPLKYADLLDIAQQVAVGMEFLAQNKVVHRDLAARNVLISVDRSIK 756 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 I DFGL++ V + Y + G P+ W A E L + SDVWSFGV LYE+ T Sbjct 757 IADFGLSRDVYHENVYRKSGGSGKLPIKWLALESLTHQVYTSQSDVWSFGVLLYEITT-- 814 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 L G+ ++ L +LL +G R+ RP+ C E++ LM++CW + S Sbjct 815 ------------LGGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQEMFSLMESCWSSVPSH 862 Query 1159 RPTFENL 1165 RPTF L Sbjct 863 RPTFSAL 869 Score = 63.9 bits (154), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 53/186 (28%), Positives = 81/186 (44%), Gaps = 36/186 (19%) Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE--- 770 +AQQ+A + +L +VH ++ RN+L++ IK++D G LSR+ Sbjct 721 IAQQVAVGMEFLAQNKVVHRDLAARNVLIS-------VDRSIKIADFG-----LSRDVYH 768 Query 771 ERVER---------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 E V R I WLA E L ++ D W FG L EI G P S SPS Sbjct 769 ENVYRKSGGSGKLPIKWLALESLTHQV--YTSQSDVWSFGVLLYEITTLGGMPYPSVSPS 826 Query 822 EKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 + ++ HR+ PE ++ +L C + P+ RP+F + H L ++ Sbjct 827 DLLQLLRQGHRMKRPEGCTQEMFSLMESCWSSVPSHRPTFSAL--------KHRLGGMIL 878 Query 880 VNPDSP 885 D P Sbjct 879 ATNDVP 884 Score = 36.6 bits (83), Expect = 2.1, Method: Compositional matrix adjust. Identities = 29/89 (33%), Positives = 44/89 (49%), Gaps = 8/89 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961 LGEG FG V Y VAVK LK + + +K EI +L+ + H +I+ Sbjct 481 LGEGAFGLVRRGVY------KKRQVAVKLLKDEPNDEDVYAFKCEIQMLKAVGKHPNIVG 534 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 G + + L++EY LGSL+++L Sbjct 535 IVGYST-RFSNQMMLLIEYCSLGSLQNFL 562 >sp|Q01887|RYK_MOUSE Tyrosine-protein kinase RYK OS=Mus musculus OX=10090 GN=Ryk PE=1 SV=2 Length=594 Score = 124 bits (312), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 95/317 (30%), Positives = 156/317 (49%), Gaps = 29/317 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRY-LKKIRDLGEGHFGKVSL-YCYDPTNDGTGE 925 R++ ++L V + + D + +R LK + L EG FG++ D + + Sbjct 289 RIEKNDLRSVTLLEAKAKVKDIAISRERITLKDV--LQEGTFGRIFHGILVDEKDPNKEK 346 Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 VK +K + E LR L+H +++ C ++GEK + +V+ Y+ G+ Sbjct 347 QTFVKTVKDQASEVQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPM-VVLPYMNWGN 405 Query 986 LRDYLPR---------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036 L+ +L + +I L+ A QI GM+YL + IHRDLAARN ++D+ Sbjct 406 LKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHRDLAARNCVIDDTLQ 465 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 VKI D L++ + +Y+ + ++ + PV W A E L +F ASDVW+FGVTL+EL+T Sbjct 466 VKITDNALSRDLFP-MDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMT 524 Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156 Q+P + I +M L+ G R+ +P CP E++ +M CW + Sbjct 525 ---LGQTP------YVDIDPFEMAA-----YLKDGYRIAQPINCPDELFAVMACCWALDP 570 Query 1157 SFRPTFENLIPILKTVH 1173 RP F+ L+ L H Sbjct 571 EERPKFQQLVQCLTEFH 587 Score = 72.8 bits (177), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 66/265 (25%), Positives = 125/265 (47%), Gaps = 36/265 (14%) Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL-MSQVSHTHLAFVHGVCVR-GPENI 684 LV +D +E + +K + ++ + T S + + H +L + VC+ G + + Sbjct 336 LVDEKDPNKEKQTFVKTVKDQASEVQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPM 395 Query 685 MVTEYVEHGPLDVWLRRER---GHVPMAWK----MVVAQQLASALSYLENKNLVHGNVCG 737 +V Y+ G L ++LR+ + + P A + +A Q+A +SYL + ++H ++ Sbjct 396 VVLPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHRDLAA 455 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSRE----------ERVER-IPWLAPECLPG 786 RN ++ + +K++D ALSR+ + R + W+A E L Sbjct 456 RNCVI-------DDTLQVKITD-----NALSRDLFPMDYHCLGDNENRPVRWMALESLVN 503 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATL 844 N S+A D W FG TL E+ G+ P P E + + +R+ +P +CP +L + Sbjct 504 --NEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAV 561 Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869 + C +P +RP F+ +++ LT Sbjct 562 MACCWALDPEERPKFQQLVQCLTEF 586 >sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kinase 11 OS=Rattus norvegicus OX=10116 GN=Map3k11 PE=1 SV=1 Length=850 Score = 125 bits (315), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 101/304 (33%), Positives = 145/304 (48%), Gaps = 43/304 (14%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ---HRSGWKQEI 948 F + L+++ +G G FGKV + GE+VAVKA + D +QE Sbjct 115 FQELRLEEV--IGIGGFGKVYRGSW------RGELVAVKAARQDPDEDISVTAESVRQEA 166 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008 + L H +II K C + E +L LVMEY G L L + L+ +A QI Sbjct 167 RLFAMLAHPNIIALKAVCLE--EPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIA 224 Query 1009 EGMAYLHAQH---YIHRDLAARNVLL----DND----RLVKIGDFGLAKAVPEGHEYYRV 1057 GM YLH + IHRDL + N+LL + D + +KI DFGLA+ E H+ ++ Sbjct 225 RGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAR---EWHKTTQM 281 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 G W APE +K F SDVWSFGV L+ELLT P + ++ + +A G Sbjct 282 SAAGT--YAWMAPEVIKASTFSKGSDVWSFGVLLWELLTG-----EVPYRGIDCLAVAYG 334 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 + V +LT LP P CP LM +CW + RP F +++ L+ + + Sbjct 335 -VAVNKLT--------LPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVL 385 Query 1178 GQAP 1181 + P Sbjct 386 REMP 389 Score = 68.6 bits (166), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 77/264 (29%), Positives = 120/264 (45%), Gaps = 26/264 (10%) Query 630 GRDRGQELRVVLKVLDPSHHDIAL---AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 G RG+ + V DP DI++ + + A L + ++H ++ + VC+ P +V Sbjct 135 GSWRGELVAVKAARQDP-DEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLV 193 Query 687 TEYVEHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKNLV---HGNVCGRNIL 741 EY GPL L RR HV + W A Q+A + YL + LV H ++ NIL Sbjct 194 MEYAAGGPLSRALAGRRVPPHVLVNW----AVQIARGMHYLHCEALVPVIHRDLKSNNIL 249 Query 742 LARLGLAEGTS---PFIKLSDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMD 796 L L EG +K++D G+ ++ W+APE + A++ S D Sbjct 250 L--LQPIEGDDMEHKTLKITDFGLAREWHKTTQMSAAGTYAWMAPEVI--KASTFSKGSD 305 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEP 853 W FG L E+ GE P + + + LP PS CP+ A L + C +P Sbjct 306 VWSFGVLLWEL-LTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDP 364 Query 854 TQRPSFRTILRDLTRLQPHNLADV 877 +RP F +IL+ L L+ L ++ Sbjct 365 HRRPDFASILQQLEALEAQVLREM 388 >sp|Q91571|EPB1A_XENLA Ephrin type-B receptor 1-A OS=Xenopus laevis OX=8355 GN=ephb1-a PE=1 SV=1 Length=985 Score = 126 bits (316), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 71/248 (29%), Positives = 127/248 (51%), Gaps = 20/248 (8%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VA+K LKA + R + E I+ H +II+ +G + + ++ E++ G+L Sbjct 649 VAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGAL 706 Query 987 RDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL Sbjct 707 DSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGL 766 Query 1045 AKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 ++ + + Y G PV W A E + KF ASDVWS+G+ ++E++++ + Sbjct 767 SRYLQDDTSDPTYTSSLGGKIPVRWTAQEAIAYRKFTSASDVWSYGIVMWEVMSYGER-- 824 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 M+ + +E+ RLP P CP ++ LM +CW+ + + RP Sbjct 825 ------------PYWTMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRL 872 Query 1163 ENLIPILK 1170 ++ L+ Sbjct 873 AEIVNTLR 880 Score = 84.7 bits (208), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 78/315 (25%), Positives = 138/315 (44%), Gaps = 50/315 (16%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653 +G G VY+GRL++ P + +E+ V +K L + + Sbjct 626 IGAGEFGEVYKGRLKL------------------PSK---REISVAIKTLKAGYSEKQRR 664 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F AS+M Q H ++ + GV + +++TE++E+G LD +LR+ G + + Sbjct 665 DFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVG 724 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 + + +A+ + YL N VH ++ RNIL+ ++ K+SD GL +++ Sbjct 725 MLRGIAAGMKYLSEMNYVHRDLAARNILV-------NSNLVCKVSD--FGLSRYLQDDTS 775 Query 774 E---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + +IP W A E + ++A D W +G + E+ GE P + S + Sbjct 776 DPTYTSSLGGKIPVRWTAQEAI--AYRKFTSASDVWSYGIVMWEVMSYGERPYWTMSNQD 833 Query 823 KEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL--QPHNLADVL 878 + ++ +RLP P CP L L C + RP I+ L + P +L V Sbjct 834 VINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRLAEIVNTLRPMIRNPASLKTVA 893 Query 879 TV--NPDSPASDPTV 891 T+ P P D ++ Sbjct 894 TIPAVPSQPLLDRSI 908 >sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase kinase 11 OS=Mus musculus OX=10090 GN=Map3k11 PE=1 SV=1 Length=850 Score = 125 bits (315), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 101/304 (33%), Positives = 145/304 (48%), Gaps = 43/304 (14%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ---HRSGWKQEI 948 F + L+++ +G G FGKV + GE+VAVKA + D +QE Sbjct 115 FQELRLEEV--IGIGGFGKVYRGSW------RGELVAVKAARQDPDEDISVTAESVRQEA 166 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008 + L H +II K C + E +L LVMEY G L L + L+ +A QI Sbjct 167 RLFAMLAHPNIIALKAVCLE--EPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIA 224 Query 1009 EGMAYLHAQH---YIHRDLAARNVLL----DND----RLVKIGDFGLAKAVPEGHEYYRV 1057 GM YLH + IHRDL + N+LL + D + +KI DFGLA+ E H+ ++ Sbjct 225 RGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAR---EWHKTTQM 281 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 G W APE +K F SDVWSFGV L+ELLT P + ++ + +A G Sbjct 282 SAAGT--YAWMAPEVIKASTFSKGSDVWSFGVLLWELLTG-----EVPYRGIDCLAVAYG 334 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 + V +LT LP P CP LM +CW + RP F +++ L+ + + Sbjct 335 -VAVNKLT--------LPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVL 385 Query 1178 GQAP 1181 + P Sbjct 386 REMP 389 Score = 68.2 bits (165), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 77/264 (29%), Positives = 120/264 (45%), Gaps = 26/264 (10%) Query 630 GRDRGQELRVVLKVLDPSHHDIAL---AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 G RG+ + V DP DI++ + + A L + ++H ++ + VC+ P +V Sbjct 135 GSWRGELVAVKAARQDP-DEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLV 193 Query 687 TEYVEHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKNLV---HGNVCGRNIL 741 EY GPL L RR HV + W A Q+A + YL + LV H ++ NIL Sbjct 194 MEYAAGGPLSRALAGRRVPPHVLVNW----AVQIARGMHYLHCEALVPVIHRDLKSNNIL 249 Query 742 LARLGLAEGTS---PFIKLSDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMD 796 L L EG +K++D G+ ++ W+APE + A++ S D Sbjct 250 L--LQPIEGDDMEHKTLKITDFGLAREWHKTTQMSAAGTYAWMAPEVI--KASTFSKGSD 305 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEP 853 W FG L E+ GE P + + + LP PS CP+ A L + C +P Sbjct 306 VWSFGVLLWEL-LTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDP 364 Query 854 TQRPSFRTILRDLTRLQPHNLADV 877 +RP F +IL+ L L+ L ++ Sbjct 365 HRRPDFASILQQLEALEAQVLREM 388 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens OX=9606 GN=MAP3K11 PE=1 SV=1 Length=847 Score = 125 bits (315), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 101/304 (33%), Positives = 146/304 (48%), Gaps = 43/304 (14%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ---HRSGWKQEI 948 F + L+++ +G G FGKV + GE+VAVKA + D +QE Sbjct 114 FQELRLEEV--IGIGGFGKVYRGSW------RGELVAVKAARQDPDEDISVTAESVRQEA 165 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008 + L H +II K C + E +L LVMEY G L L + L+ +A QI Sbjct 166 RLFAMLAHPNIIALKAVCLE--EPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIA 223 Query 1009 EGMAYLHAQH---YIHRDLAARNVLL----DND----RLVKIGDFGLAKAVPEGHEYYRV 1057 GM YLH + IHRDL + N+LL ++D + +KI DFGLA+ E H+ ++ Sbjct 224 RGMHYLHCEALVPVIHRDLKSNNILLLQPIESDDMEHKTLKITDFGLAR---EWHKTTQM 280 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 G W APE +K F SDVWSFGV L+ELLT P + ++ + +A G Sbjct 281 SAAGT--YAWMAPEVIKASTFSKGSDVWSFGVLLWELLTG-----EVPYRGIDCLAVAYG 333 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 + V +LT LP P CP LM +CW + RP F +++ L+ + + Sbjct 334 -VAVNKLT--------LPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVL 384 Query 1178 GQAP 1181 + P Sbjct 385 REMP 388 Score = 67.4 bits (163), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 74/262 (28%), Positives = 120/262 (46%), Gaps = 22/262 (8%) Query 630 GRDRGQELRVVLKVLDPSHHDIAL---AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 G RG+ + V DP DI++ + + A L + ++H ++ + VC+ P +V Sbjct 134 GSWRGELVAVKAARQDP-DEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLV 192 Query 687 TEYVEHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKNLV---HGNVCGRNIL 741 EY GPL L RR HV + W A Q+A + YL + LV H ++ NIL Sbjct 193 MEYAAGGPLSRALAGRRVPPHVLVNW----AVQIARGMHYLHCEALVPVIHRDLKSNNIL 248 Query 742 LAR-LGLAEGTSPFIKLSDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMDKW 798 L + + + +K++D G+ ++ W+APE + A++ S D W Sbjct 249 LLQPIESDDMEHKTLKITDFGLAREWHKTTQMSAAGTYAWMAPEVI--KASTFSKGSDVW 306 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQ 855 FG L E+ GE P + + + LP PS CP+ A L + C +P + Sbjct 307 SFGVLLWEL-LTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHR 365 Query 856 RPSFRTILRDLTRLQPHNLADV 877 RP F +IL+ L L+ L ++ Sbjct 366 RPDFASILQQLEALEAQVLREM 387 >sp|O13147|EPHB3_DANRE Ephrin type-B receptor 3 (Fragment) OS=Danio rerio OX=7955 GN=ephb3 PE=2 SV=1 Length=500 Score = 122 bits (307), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 82/273 (30%), Positives = 131/273 (48%), Gaps = 25/273 (9%) Query 903 LGEGHFGKVSLYCYDPTND-GTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G FG+V C G E VA+K LKA R + E I+ H ++I Sbjct 193 IGAGEFGEV---CRGRLKQAGRKETTVAIKTLKAGYTEHQRRDFLSEASIMGQFDHPNVI 249 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018 +G + +V E++ G+L +L + + QL+ + I GM YL + Sbjct 250 HLEGVLTRSC--PVLIVTEFMENGALDSFLRLNDGRFTVTQLVGMLRGIAAGMKYLSDMN 307 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076 Y+HRDLAARNVL++++ + K+ DFGL++ + + Y G P+ W APE + Sbjct 308 YVHRDLAARNVLVNSNLVCKVSDFGLSRFLDDNSSDPTYTSSLGGKIPIRWTAPEAIAFR 367 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 KF ASDVWS+G+ ++E+++ + M+ + +E+ RLP Sbjct 368 KFTSASDVWSYGIVMWEVMSFGER--------------PYWDMSNQDVMNAVEQDYRLPP 413 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P CP ++ LM CW E + RP F ++ L Sbjct 414 PMDCPAVLHQLMLECWVKERNMRPRFGQIVSTL 446 Score = 88.2 bits (217), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 66/227 (29%), Positives = 106/227 (47%), Gaps = 22/227 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F AS+M Q H ++ + GV R ++VTE++E+G LD +LR G + + + Sbjct 233 FLSEASIMGQFDHPNVIHLEGVLTRSCPVLIVTEFMENGALDSFLRLNDGRFTVTQLVGM 292 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFI--KLSDPGV--GLGA 766 + +A+ + YL + N VH ++ RN+L+ + + G S F+ SDP LG Sbjct 293 LRGIAAGMKYLSDMNYVHRDLAARNVLVNSNLVCKVSDFGLSRFLDDNSSDPTYTSSLGG 352 Query 767 LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 +IP W APE + ++A D W +G + E+ GE P S + Sbjct 353 --------KIPIRWTAPEAI--AFRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVM 402 Query 825 HFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + ++ +RLP P CP L L +C E RP F I+ L + Sbjct 403 NAVEQDYRLPPPMDCPAVLHQLMLECWVKERNMRPRFGQIVSTLDKF 449 >sp|Q9I8N6|CSF1R_DANRE Macrophage colony-stimulating factor 1 receptor OS=Danio rerio OX=7955 GN=csf1r PE=2 SV=1 Length=977 Score = 125 bits (315), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 106/394 (27%), Positives = 169/394 (43%), Gaps = 89/394 (23%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS-PASDPTVFHKRYLKKIRDLGEGH 907 + Y+ Q+P + + + +N ++P P ++ F + LK + LG G Sbjct 538 MIYKYKQKPRYEIRWKIIEATNGNNYT---FIDPTQLPYNEKWEFPRDKLKLGKTLGAGA 594 Query 908 FGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKG- 964 FGKV Y + VAVK LKA P R E+ IL L H++I+ G Sbjct 595 FGKVVEATAYGLGKEDNITRVAVKMLKASAHPDEREALMSELKILSHLGQHKNIVNLLGA 654 Query 965 -------------CC--------EDQGEKSLQLVM----------EYVPLGSLRDYL--- 990 CC + E L VM +Y + + R ++ Sbjct 655 CTHGGPVLVITEYCCHGDLLNFLRSKAENFLNFVMTIPNFPEPMTDYKNVSTERMFVRSD 714 Query 991 --------------------PRHS--------------IGLAQLLLFAQQICEGMAYLHA 1016 P +S + + LL F+ Q+ +G+ +L A Sbjct 715 SGISSTCSDHYLDMRPVTSRPTNSALDSSSECQEDSWPLDMDDLLRFSSQVAQGLDFLAA 774 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 ++ IHRD+AARNVLL N R+ KI DFGLA+ + Y V+ + PV W APE + E Sbjct 775 KNCIHRDVAARNVLLTNSRVAKICDFGLARDIMNDSNYV-VKGNARLPVKWMAPESIFEC 833 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 + SDVWS+G+ L+E+ + +SP L + ++++ G ++ R Sbjct 834 VYTVQSDVWSYGIMLWEIFSL---GKSPYPNIL----------VDSKFYKMIKCGYQMSR 880 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 PD P E+Y +MK CW +A+ RPTF + +++ Sbjct 881 PDFAPPEMYTIMKMCWNLDAAERPTFSKISQMIQ 914 Score = 57.8 bits (138), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 42/166 (25%), Positives = 76/166 (46%), Gaps = 22/166 (13%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + Q+A L +L KN +H +V RN+LL +A K+ D G+ ++ V Sbjct 762 SSQVAQGLDFLAAKNCIHRDVAARNVLLTNSRVA-------KICDFGLARDIMNDSNYVV 814 Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 + + W+APE + ++ + D W +G L EI G++P + K FY+ Sbjct 815 KGNARLPVKWMAPESIFECVYTVQS--DVWSYGIMLWEIFSLGKSPYPNILVDSK--FYK 870 Query 829 R-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 Q P+ + P++ T+ C + +RP+F I + + R+ Sbjct 871 MIKCGYQMSRPDFAPPEMYTIMKMCWNLDAAERPTFSKISQMIQRM 916 >sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens OX=9606 GN=EPHB4 PE=1 SV=2 Length=987 Score = 125 bits (314), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 81/280 (29%), Positives = 136/280 (49%), Gaps = 25/280 (9%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTND-GTGE-MVAVKALKADCGPQHRSGWKQEIDILRT 953 Y+K +G G FG+V C G E VA+K LK + R + E I+ Sbjct 614 YVKIEEVIGAGEFGEV---CRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQ 670 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGM 1011 H +II+ +G + + ++ E++ G+L +L + + QL+ + I GM Sbjct 671 FEHPNIIRLEGVVTNS--MPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYA 1069 YL Y+HRDLAARN+L++++ + K+ DFGL++ + E Y G P+ W A Sbjct 729 RYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTA 788 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE + KF ASD WS+G+ ++E+++ + M+ + +E Sbjct 789 PEAIAFRKFTSASDAWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIE 834 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + RLP P CP ++ LM +CW+ + + RP F ++ L Sbjct 835 QDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSAL 874 Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 64/254 (25%), Positives = 113/254 (44%), Gaps = 24/254 (9%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F AS+M Q H ++ + GV +++TE++E+G LD +LR G + + + Sbjct 661 FLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGM 720 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + +AS + YL + VH ++ RNIL+ ++ K+SD GL E + Sbjct 721 LRGIASGMRYLAEMSYVHRDLAARNILV-------NSNLVCKVSD--FGLSRFLEENSSD 771 Query 775 ---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 +IP W APE + ++A D W +G + E+ GE P S + Sbjct 772 PTYTSSLGGKIPIRWTAPEAI--AFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDV 829 Query 824 EHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 + ++ +RL P P CP L L C + RP F ++ L ++ + + + Sbjct 830 INAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVAR 889 Query 882 PDSPASDPTVFHKR 895 + AS P + ++ Sbjct 890 ENGGASHPLLDQRQ 903 >sp|O73878|EPB4B_DANRE Ephrin type-B receptor 4b OS=Danio rerio OX=7955 GN=ephb4b PE=1 SV=2 Length=976 Score = 125 bits (314), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 83/280 (30%), Positives = 135/280 (48%), Gaps = 25/280 (9%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTN-DGTGE-MVAVKALKADCGPQHRSGWKQEIDILRT 953 ++K +G G FG+V C G E VA+K LK + R + E I+ Sbjct 612 FVKIEEVIGAGEFGEV---CRGRLKVPGKKENYVAIKTLKGGYTDKQRRDFLSEASIMGQ 668 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGM 1011 H +II +G + ++ EY+ G+L +L + QL+ + I GM Sbjct 669 FQHPNIIHLEGVI--TASCPVMILTEYMENGALDSFLRLNDGQFTPIQLVGMLRGIASGM 726 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYA 1069 YL ++HRDLAARN+L++++ + K+ DFGL++ + E Y G P+ W A Sbjct 727 KYLSEMSFVHRDLAARNILVNSNLVCKVSDFGLSRFLTENSSDPTYTSSLGGKIPIRWTA 786 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE + KF ASDVWS+G+ ++E+++ + M+ + +E Sbjct 787 PEAIAFRKFTSASDVWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIE 832 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + RLP P +CP ++ LM +CW+ E S RP F ++ L Sbjct 833 QDYRLPPPPECPASLHQLMLDCWQKERSSRPRFCAIVSAL 872 Score = 87.8 bits (216), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 79/275 (29%), Positives = 123/275 (45%), Gaps = 31/275 (11%) Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 VPG+ +E V +K L + D F AS+M Q H ++ + GV +++ Sbjct 634 VPGK---KENYVAIKTLKGGYTDKQRRDFLSEASIMGQFQHPNIIHLEGVITASCPVMIL 690 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TEY+E+G LD +LR G + + + +AS + YL + VH ++ RNIL+ Sbjct 691 TEYMENGALDSFLRLNDGQFTPIQLVGMLRGIASGMKYLSEMSFVHRDLAARNILV---- 746 Query 747 LAEGTSPFIKLSDPGVGLGALSREERVE---------RIP--WLAPECLPGGANSLSTAM 795 ++ K+SD GL E + +IP W APE + ++A Sbjct 747 ---NSNLVCKVSD--FGLSRFLTENSSDPTYTSSLGGKIPIRWTAPEAI--AFRKFTSAS 799 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEP 853 D W +G + E+ GE P S + + ++ +RL P P CP L L C E Sbjct 800 DVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPECPASLHQLMLDCWQKER 859 Query 854 TQRPSFRTILRDLTRL--QPHNLADVLTVNPDSPA 886 + RP F I+ L RL P +L + PD P+ Sbjct 860 SSRPRFCAIVSALDRLIRNPASLKITGRI-PDGPS 893 >sp|P30530|UFO_HUMAN Tyrosine-protein kinase receptor UFO OS=Homo sapiens OX=9606 GN=AXL PE=1 SV=4 Length=894 Score = 125 bits (313), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 91/285 (32%), Positives = 134/285 (47%), Gaps = 31/285 (11%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDIL 951 HK L K LGEG FG V + D + VAVK +K A C + E + Sbjct 534 HKVALGKT--LGEGEFGAVMEGQLN--QDDSILKVAVKTMKIAICTRSELEDFLSEAVCM 589 Query 952 RTLYHEHIIKYKGCCEDQGEK----SLQLVMEYVPLGSLRDYLPRHSIG-------LAQL 1000 + H ++++ G C E+ + +++ ++ G L +L +G L Sbjct 590 KEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGDQPVYLPTQML 649 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 + F I GM YL + +IHRDLAARN +L+ + V + DFGL+K + G +YYR Sbjct 650 VKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNG-DYYRQGRI 708 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 PV W A E L + + SDVWSFGVT++E+ T Q+P G+ + Sbjct 709 AKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATR---GQTP------YPGVENSE-- 757 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + L +G RL +P C +Y LM CWE RP+F L Sbjct 758 ---IYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTEL 799 Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 82/316 (26%), Positives = 135/316 (43%), Gaps = 55/316 (17%) Query 600 RTNVYEGRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA---- 654 R V G+ EG G EG+++ +D + L+V +K + IA+ Sbjct 533 RHKVALGKTLGEGEFGAVMEGQLNQDDSI---------LKVAVKTMK-----IAICTRSE 578 Query 655 ---FYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEYVEHGPLDVWLRRER-- 703 F A M + H ++ + GVC +G P +++ +++HG L +L R Sbjct 579 LEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLG 638 Query 704 ---GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 ++P + +AS + YL K +H ++ RN +L E S + ++D Sbjct 639 DQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLN-----ENMS--VCVADF 691 Query 761 GVGL----GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ G R+ R+ ++P W+A E L ++ D W FG T+ EI G+ P Sbjct 692 GLSKKIYNGDYYRQGRIAKMPVKWIAIESL--ADRVYTSKSDVWSFGVTMWEIATRGQTP 749 Query 815 LQSRSPSEKEHFYQRQHRLPEPS--CPQLATLTSQCLTYEPTQRPSFRTILRDLTR---- 868 SE + ++ +RL +P+ L L S+C P RPSF + DL Sbjct 750 YPGVENSEIYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTELREDLENTLKA 809 Query 869 LQPHNLAD-VLTVNPD 883 L P D +L VN D Sbjct 810 LPPAQEPDEILYVNMD 825 >sp|O73792|TIE1_DANRE Tyrosine-protein kinase receptor Tie-1 (Fragment) OS=Danio rerio OX=7955 GN=tie1 PE=1 SV=1 Length=184 Score = 114 bits (285), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 69/176 (39%), Positives = 90/176 (51%), Gaps = 18/176 (10%) Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 QLL FA + GM YL + +IHRDLAARNVL+ ++ + KI DFGL++ G E Y + Sbjct 1 QLLQFAADVATGMHYLSDKQFIHRDLAARNVLVGDNLVAKIADFGLSR----GEEVYVKK 56 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 G PV W A E L + SDVWSFGV L+E+++ L G Sbjct 57 TMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCG 102 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 MT L E L +G R+ +P C EVY LM+ CW RP F + L + E Sbjct 103 MTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRMQE 158 Score = 59.7 bits (143), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 47/168 (28%), Positives = 79/168 (47%), Gaps = 14/168 (8%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERV 773 A +A+ + YL +K +H ++ RN+L+ G + K++D G+ G + ++ + Sbjct 6 AADVATGMHYLSDKQFIHRDLAARNVLV-------GDNLVAKIADFGLSRGEEVYVKKTM 58 Query 774 ERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 R+P W+A E L + +T D W FG L EI G P + +E + + Sbjct 59 GRLPVRWMAIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGY 116 Query 832 RLPEP-SC-PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 R+ +P +C ++ L QC P +RP F I L R+Q A V Sbjct 117 RMEQPRNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRMQEARKAYV 164 >sp|P97793|ALK_MOUSE ALK tyrosine kinase receptor OS=Mus musculus OX=10090 GN=Alk PE=1 SV=2 Length=1621 Score = 125 bits (314), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 100/330 (30%), Positives = 146/330 (44%), Gaps = 41/330 (12%) Query 855 QRPSFR-TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV-S 912 Q P ++ + LR T + +N + S SD ++ + IR LG G FG+V Sbjct 1078 QSPEYKLSKLRTSTIMTDYN-PNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYE 1136 Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972 ND + VAVK L C Q + E I+ H++I++ G Sbjct 1137 GQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGV------- 1189 Query 973 SLQ-----LVMEYVPLGSLRDYL----PR----HSIGLAQLLLFAQQICEGMAYLHAQHY 1019 SLQ +++E + G L+ +L PR S+ + LL A+ I G YL H+ Sbjct 1190 SLQALPRFILLELMAGGDLKSFLRETRPRPNQPTSLAMLDLLHVARDIACGCQYLEENHF 1249 Query 1020 IHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+AARN LL R+ KIGDFG+A+ + YYR PV W PE E Sbjct 1250 IHRDIAARNCLLTCPGAGRIAKIGDFGMARDIYRA-SYYRKGGCAMLPVKWMPPEAFMEG 1308 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 F +D WSFGV L+E+ + L + + + E + G R+ Sbjct 1309 IFTSKTDTWSFGVLLWEIFS--------------LGYMPYPSKSNQEVLEFVTSGGRMDP 1354 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 P CP VY +M CW+ + RP F ++ Sbjct 1355 PKNCPGPVYRIMTQCWQHQPEDRPNFAIIL 1384 Score = 84.3 bits (207), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 85/310 (27%), Positives = 135/310 (44%), Gaps = 42/310 (14%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 +T ++S L V +K IT + LG G VYEG++ SG P +D PL Sbjct 1105 KTSSISDLK--EVPRKNITLIRGLGHGAFGEVYEGQV----SGMP-----NDPSPL---- 1149 Query 632 DRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 +V +K L + L F A ++S+ +H ++ GV ++ ++ E + Sbjct 1150 ------QVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELM 1203 Query 691 EHGPLDVWLR--RERGHVPMAWKMV----VAQQLASALSYLENKNLVHGNVCGRNILLAR 744 G L +LR R R + P + M+ VA+ +A YLE + +H ++ RN LL Sbjct 1204 AGGDLKSFLRETRPRPNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLT- 1262 Query 745 LGLAEGTSPFIKLSDPGVG----LGALSREERVERIP--WLAPECLPGGANSLSTAMDKW 798 G K+ D G+ + R+ +P W+ PE G ++ D W Sbjct 1263 ---CPGAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGI--FTSKTDTW 1317 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQR 856 FG L EI G P S+S E F R+ P +CP + + +QC ++P R Sbjct 1318 SFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDR 1377 Query 857 PSFRTILRDL 866 P+F IL + Sbjct 1378 PNFAIILERI 1387 >sp|Q5JZY3|EPHAA_HUMAN Ephrin type-A receptor 10 OS=Homo sapiens OX=9606 GN=EPHA10 PE=1 SV=2 Length=1008 Score = 124 bits (312), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 87/275 (32%), Positives = 127/275 (46%), Gaps = 23/275 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 R LG G FG++ C G E+ VAV L+ R G+ E L H HI Sbjct 649 RSLGGGRFGELCCGCLQ--LPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHI 706 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQ 1017 ++ +G +L +V EY+ G+L +L RH L QL+ + M YL Sbjct 707 VRLEGVVTRG--STLMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEM 764 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 Y+HR LAAR+VL+ +D + KI FG + + E G SP W APE L+ Sbjct 765 GYVHRGLAARHVLVSSDLVCKISGFG--RGPRDRSEAVYTTMSGRSPALWAAPETLQFGH 822 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F ASDVWSFG+ ++E++ + M+ + + +E G RLP P Sbjct 823 FSSASDVWSFGIIMWEVMAFGERP--------------YWDMSGQDVIKAVEDGFRLPPP 868 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 CP ++ LM +CW+ + RP F + IL + Sbjct 869 RNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKM 903 Score = 105 bits (262), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 90/275 (33%), Positives = 125/275 (45%), Gaps = 28/275 (10%) Query 628 VPGRDRGQELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 +PGR QEL V + +L S D L F A + Q H+H+ + GV RG ++V Sbjct 666 LPGR---QELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIV 722 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TEY+ HG LD +LRR G + M + LASA+ YL VH + R++L++ Sbjct 723 TEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVS--- 779 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-----ERIP--WLAPECLPGGANSLSTAMDKWG 799 + K+S G G G R E V R P W APE L G S+A D W Sbjct 780 ----SDLVCKIS--GFGRGPRDRSEAVYTTMSGRSPALWAAPETLQFG--HFSSASDVWS 831 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQLA-TLTSQCLTYEPTQRP 857 FG + E+ GE P S + + RLP P +CP L L C +P +RP Sbjct 832 FGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERP 891 Query 858 SFRTILRDLTRL----QPHNLADVLTVNPDSPASD 888 F I L+++ +P A P +P +D Sbjct 892 RFSQIHSILSKMVQDPEPPKCALTTCPRPPTPLAD 926 >sp|O73875|EPB4A_DANRE Ephrin type-B receptor 4a OS=Danio rerio OX=7955 GN=ephb4a PE=1 SV=3 Length=987 Score = 124 bits (312), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 74/247 (30%), Positives = 122/247 (49%), Gaps = 20/247 (8%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VA+K LK + R + E I+ H +II +G + ++ E++ G+L Sbjct 650 VAIKTLKGGYTDKQRRDFLAEASIMGQFQHPNIIHLEGII--TASCPVMILTEFMENGAL 707 Query 987 RDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 +L + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL Sbjct 708 DSFLRLNDGQFTPIQLVGMLRGIASGMKYLSEMSYVHRDLAARNILVNSNLVCKVSDFGL 767 Query 1045 AKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 ++ + E Y G P+ W APE + KF ASDVWS+G+ ++E+++ + Sbjct 768 SRFLQENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTCASDVWSYGIVMWEVMSFGER-- 825 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 M+ + +E+ RLP P CP ++ LM +CW+ E + RP F Sbjct 826 ------------PYWDMSNQDVINAIEQDYRLPPPPDCPTYLHQLMLDCWQKERTARPRF 873 Query 1163 ENLIPIL 1169 N++ L Sbjct 874 ANIVSAL 880 Score = 84.7 bits (208), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 78/289 (27%), Positives = 123/289 (43%), Gaps = 46/289 (16%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653 +G G V GRLR+ PG+ +E V +K L + D Sbjct 627 IGAGEFGEVCRGRLRI------------------PGK---KENYVAIKTLKGGYTDKQRR 665 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F AS+M Q H ++ + G+ +++TE++E+G LD +LR G + Sbjct 666 DFLAEASIMGQFQHPNIIHLEGIITASCPVMILTEFMENGALDSFLRLNDGQFTPIQLVG 725 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 + + +AS + YL + VH ++ RNIL+ ++ K+SD GL +E Sbjct 726 MLRGIASGMKYLSEMSYVHRDLAARNILV-------NSNLVCKVSD--FGLSRFLQENSS 776 Query 774 E---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + +IP W APE + + A D W +G + E+ GE P S + Sbjct 777 DPTYTSSLGGKIPIRWTAPEAI--AFRKFTCASDVWSYGIVMWEVMSFGERPYWDMSNQD 834 Query 823 KEHFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + ++ +RL P P CP L L C E T RP F I+ L +L Sbjct 835 VINAIEQDYRLPPPPDCPTYLHQLMLDCWQKERTARPRFANIVSALDKL 883 >sp|P08923|LTK_MOUSE Leukocyte tyrosine kinase receptor OS=Mus musculus OX=10090 GN=Ltk PE=1 SV=3 Length=888 Score = 124 bits (312), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 94/300 (31%), Positives = 140/300 (47%), Gaps = 38/300 (13%) Query 900 IRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +R LG G FG+V L P D + VA+K L C Q + E I+ H+ Sbjct 509 LRALGHGAFGEVYEGLVTGLP-GDSSPLPVAIKTLPELCSHQDELDFLMEALIISKFSHQ 567 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------IGLAQLLLFAQQIC 1008 +I++ G + +++E + G ++ +L RHS + + LL AQ I Sbjct 568 NIVRCVGLSFRSAPR--LILLELMSGGDMKSFL-RHSRPHPGQLAPLTMQDLLQLAQDIA 624 Query 1009 EGMAYLHAQHYIHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 +G YL H+IHRD+AARN LL R+ KIGDFG+A+ + + YYR PV Sbjct 625 QGCHYLEENHFIHRDIAARNCLLSCSGASRVAKIGDFGMARDIYQA-SYYRKGGRTLLPV 683 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 W PE L E F +D WSFGV L+E+ + ++ G T + Sbjct 684 KWMPPEALLEGLFTSKTDSWSFGVLLWEIFS---------LGYMPYPG-----HTNQEVL 729 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 + + G R+ P CP VY +M CW+ + RP F + IL+ + +Y Q P V + Sbjct 730 DFIATGNRMDPPRNCPGPVYRIMTQCWQHQPELRPDFGS---ILERI--QYCTQDPDVLN 784 Score = 80.9 bits (198), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 86/317 (27%), Positives = 130/317 (41%), Gaps = 44/317 (14%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +T L LG G VYEG + G D PL V +K Sbjct 501 VSPANVTLLRALGHGAFGEVYEGLV---------TGLPGDSSPL----------PVAIKT 541 Query 644 LDP--SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 L SH D L F A ++S+ SH ++ G+ R +++ E + G + +LR Sbjct 542 LPELCSHQD-ELDFLMEALIISKFSHQNIVRCVGLSFRSAPRLILLELMSGGDMKSFLRH 600 Query 702 ERGH----VPMAWK--MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 R H P+ + + +AQ +A YLE + +H ++ RN LL+ G S Sbjct 601 SRPHPGQLAPLTMQDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLS----CSGASRVA 656 Query 756 KLSDPGVG----LGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 K+ D G+ + R+ +P W+ PE L G ++ D W FG L EI Sbjct 657 KIGDFGMARDIYQASYYRKGGRTLLPVKWMPPEALLEGL--FTSKTDSWSFGVLLWEIFS 714 Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLT 867 G P + E F +R+ P +CP + + +QC ++P RP F +IL + Sbjct 715 LGYMPYPGHTNQEVLDFIATGNRMDPPRNCPGPVYRIMTQCWQHQPELRPDFGSILERIQ 774 Query 868 RL--QPHNLADVLTVNP 882 P L L V P Sbjct 775 YCTQDPDVLNSPLPVEP 791 >sp|P54761|EPHB4_MOUSE Ephrin type-B receptor 4 OS=Mus musculus OX=10090 GN=Ephb4 PE=1 SV=2 Length=987 Score = 124 bits (312), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 81/280 (29%), Positives = 136/280 (49%), Gaps = 25/280 (9%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTND-GTGE-MVAVKALKADCGPQHRSGWKQEIDILRT 953 Y+K +G G FG+V C G E VA+K LK + R + E I+ Sbjct 614 YVKIEEVIGAGEFGEV---CRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMGQ 670 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGM 1011 H +II+ +G + + ++ E++ G+L +L + + QL+ + I GM Sbjct 671 FEHPNIIRLEGVVTNS--VPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYA 1069 YL Y+HRDLAARN+L++++ + K+ DFGL++ + E Y G P+ W A Sbjct 729 RYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTA 788 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE + KF ASD WS+G+ ++E+++ + M+ + +E Sbjct 789 PEAIAFRKFTSASDAWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIE 834 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + RLP P CP ++ LM +CW+ + + RP F ++ L Sbjct 835 QDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSAL 874 Score = 80.1 bits (196), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 64/248 (26%), Positives = 110/248 (44%), Gaps = 24/248 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F AS+M Q H ++ + GV +++TE++E+G LD +LR G + + + Sbjct 661 FLSEASIMGQFEHPNIIRLEGVVTNSVPVMILTEFMENGALDSFLRLNDGQFTVIQLVGM 720 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + +AS + YL + VH ++ RNIL+ ++ K+SD GL E + Sbjct 721 LRGIASGMRYLAEMSYVHRDLAARNILV-------NSNLVCKVSD--FGLSRFLEENSSD 771 Query 775 ---------RIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 +IP W APE + ++A D W +G + E+ GE P S + Sbjct 772 PTYTSSLGGKIPIRWTAPEAI--AFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDV 829 Query 824 EHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 + ++ +RL P P CP L L C + RP F ++ L ++ + + + Sbjct 830 INAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVAR 889 Query 882 PDSPASDP 889 + AS P Sbjct 890 ENGGASHP 897 >sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens OX=9606 GN=MAP3K3 PE=1 SV=2 Length=626 Score = 123 bits (308), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 73/200 (37%), Positives = 114/200 (57%), Gaps = 11/200 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP----QHRSGWKQEIDILRTLYHEH 958 LG+G FG+V L CYD TG +A K ++ D + S + EI +L+ L HE Sbjct 368 LGQGAFGRVYL-CYDVD---TGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHER 423 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQ 1017 I++Y GC D+ EK+L + MEY+P GS++D L + ++ + + +QI EGM+YLH+ Sbjct 424 IVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSN 483 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRD+ N+L D+ VK+GDFG +K + +R +P +W +PE + Sbjct 484 MIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTP-YWMSPEVISGE 542 Query 1077 KFYYASDVWSFGVTLYELLT 1096 + +DVWS G T+ E+LT Sbjct 543 GYGRKADVWSLGCTVVEMLT 562 Score = 37.4 bits (85), Expect = 1.0, Method: Compositional matrix adjust. Identities = 62/257 (24%), Positives = 98/257 (38%), Gaps = 47/257 (18%) Query 632 DRGQELRVVLKVLDPSHHDIAL---AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT- 687 D G+EL DP + + A L+ + H + +G C+R +T Sbjct 383 DTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYG-CLRDRAEKTLTI 441 Query 688 --EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 EY+ G + L+ G + + +Q+ +SYL + +VH ++ G NIL Sbjct 442 FMEYMPGGSVKDQLK-AYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSA 500 Query 746 GLAEGTSPFIKLSDPGV----------GLGALSREERVERIP-WLAPECLPGGANSLSTA 794 G +KL D G G G S V P W++PE + G Sbjct 501 G-------NVKLGDFGASKRLQTICMSGTGMRS----VTGTPYWMSPEVISG--EGYGRK 547 Query 795 MDKWGFGATLLEICFDGEAPLQSRSP-SEKEHFYQRQHRLPEPSCPQLATLTSQC----- 848 D W G T++E+ L + P +E E +P+ PQL + S+ Sbjct 548 ADVWSLGCTVVEM-------LTEKPPWAEYEAMAAIFKIATQPTNPQLPSHISEHGRDFL 600 Query 849 --LTYEPTQRPSFRTIL 863 + E QRPS +L Sbjct 601 RRIFVEARQRPSAEELL 617 >sp|Q00993|UFO_MOUSE Tyrosine-protein kinase receptor UFO OS=Mus musculus OX=10090 GN=Axl PE=1 SV=2 Length=888 Score = 124 bits (311), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 91/285 (32%), Positives = 134/285 (47%), Gaps = 31/285 (11%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDIL 951 HK L K LGEG FG V + D + VAVK +K A C + E + Sbjct 528 HKVALGKT--LGEGEFGAVMEGQLN--QDDSILKVAVKTMKIAICTRSELEDFLSEAVCM 583 Query 952 RTLYHEHIIKYKGCC----EDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-------LAQL 1000 + H ++++ G C + +G +++ ++ G L +L +G L Sbjct 584 KEFDHPNVMRLIGVCFQGSDREGFPEPVVILPFMKHGDLHSFLLYSRLGDQPVFLPTQML 643 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 + F I GM YL + +IHRDLAARN +L+ + V + DFGL+K + G +YYR Sbjct 644 VKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNG-DYYRQGRI 702 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 PV W A E L + + SDVWSFGVT++E+ T Q+P G+ + Sbjct 703 AKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATR---GQTP------YPGVENSE-- 751 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + L +G RL +P C +Y LM CWE RP+F L Sbjct 752 ---IYDYLRQGNRLKQPVDCLDGLYALMSRCWELNPRDRPSFAEL 793 Score = 76.3 bits (186), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 87/320 (27%), Positives = 139/320 (43%), Gaps = 55/320 (17%) Query 600 RTNVYEGRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA---- 654 R V G+ EG G EG+++ +D + L+V +K + IA+ Sbjct 527 RHKVALGKTLGEGEFGAVMEGQLNQDDSI---------LKVAVKTMK-----IAICTRSE 572 Query 655 ---FYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEYVEHGPLDVWLRRER-G 704 F A M + H ++ + GVC +G PE +++ +++HG L +L R G Sbjct 573 LEDFLSEAVCMKEFDHPNVMRLIGVCFQGSDREGFPEPVVILPFMKHGDLHSFLLYSRLG 632 Query 705 HVP--MAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 P + +M+V +AS + YL K +H ++ RN +L E S + ++D Sbjct 633 DQPVFLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLN-----ENMS--VCVADF 685 Query 761 GVGL----GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ G R+ R+ ++P W+A E L ++ D W FG T+ EI G+ P Sbjct 686 GLSKKIYNGDYYRQGRIAKMPVKWIAIESL--ADRVYTSKSDVWSFGVTMWEIATRGQTP 743 Query 815 LQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTR---- 868 SE + ++ +RL +P L L S+C P RPSF + DL Sbjct 744 YPGVENSEIYDYLRQGNRLKQPVDCLDGLYALMSRCWELNPRDRPSFAELREDLENTLKA 803 Query 869 LQPHNLAD-VLTVNPDSPAS 887 L P D +L VN D S Sbjct 804 LPPAQEPDEILYVNMDEGGS 823 >sp|P34925|RYK_HUMAN Tyrosine-protein kinase RYK OS=Homo sapiens OX=9606 GN=RYK PE=1 SV=3 Length=607 Score = 122 bits (307), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 95/317 (30%), Positives = 155/317 (49%), Gaps = 29/317 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRY-LKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926 R++ ++L V + D + +R LK + L EG FG++ D E Sbjct 302 RIEKNDLRSVTLLEAKGKVKDIAISRERITLKDV--LQEGTFGRIFHGILIDEKDPNKEK 359 Query 927 VA-VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 A VK +K + E LR L+H +++ C ++GEK + +++ Y+ G+ Sbjct 360 QAFVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPM-VILPYMNWGN 418 Query 986 LRDYLPR---------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036 L+ +L + +I L+ A QI GM+YL + IH+DLAARN ++D+ Sbjct 419 LKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTLQ 478 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 VKI D L++ + +Y+ + ++ + PV W A E L +F ASDVW+FGVTL+EL+T Sbjct 479 VKITDNALSRDLFP-MDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMT 537 Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156 Q+P + I +M L+ G R+ +P CP E++ +M CW + Sbjct 538 ---LGQTP------YVDIDPFEMAA-----YLKDGYRIAQPINCPDELFAVMACCWALDP 583 Query 1157 SFRPTFENLIPILKTVH 1173 RP F+ L+ L H Sbjct 584 EERPKFQQLVQCLTEFH 600 Score = 74.3 bits (181), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 72/312 (23%), Positives = 144/312 (46%), Gaps = 39/312 (13%) Query 583 RVDQKEITQLSHL-GQGTRTNVYEGRLRVEGSGDPEEGKMDD--EDPLVPGRDRGQELRV 639 R+++ ++ ++ L +G ++ R R+ +EG L+ +D +E + Sbjct 302 RIEKNDLRSVTLLEAKGKVKDIAISRERITLKDVLQEGTFGRIFHGILIDEKDPNKEKQA 361 Query 640 VLKVLDPSHHDIALAFYETASL-MSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDV 697 +K + +I + T S + + H +L + VC+ G + +++ Y+ G L + Sbjct 362 FVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKL 421 Query 698 WLRRER---GHVPMAWK----MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 +LR+ + + P A + +A Q+A +SYL + ++H ++ RN ++ Sbjct 422 FLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVI-------D 474 Query 751 TSPFIKLSDPGVGLGALSRE----------ERVER-IPWLAPECLPGGANSLSTAMDKWG 799 + +K++D ALSR+ + R + W+A E L N S+A D W Sbjct 475 DTLQVKITD-----NALSRDLFPMDYHCLGDNENRPVRWMALESLVN--NEFSSASDVWA 527 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRP 857 FG TL E+ G+ P P E + + +R+ +P +CP +L + + C +P +RP Sbjct 528 FGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERP 587 Query 858 SFRTILRDLTRL 869 F+ +++ LT Sbjct 588 KFQQLVQCLTEF 599 >sp|Q07497|EPHB5_CHICK Ephrin type-B receptor 5 OS=Gallus gallus OX=9031 GN=EPHB5 PE=2 SV=1 Length=1002 Score = 124 bits (311), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 80/286 (28%), Positives = 144/286 (50%), Gaps = 25/286 (9%) Query 896 YLKKIRDLGEGHFGKVSLYCYDP-TNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRT 953 ++K +G G FG+V C+ + G E VA+K LK+ + R + E I+ Sbjct 636 FIKIEEVIGSGEFGEV---CFGRLKHPGKREYTVAIKTLKSGYTDEQRREFLSEASIMGQ 692 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGM 1011 H ++I +G + + +V E++ GSL +L + + QL+ + I GM Sbjct 693 FEHPNVIHLEGVVTKS--RPVMIVTEFMENGSLDSFLRQKEGQFSVLQLVGMLRGIAAGM 750 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE--GHEYYRVREDGDSPVFWYA 1069 YL +Y+HRDLAARN+L++++ + K+ DFGL++ + + + Y P+ W A Sbjct 751 RYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDASNPTYTGALGCKIPIRWTA 810 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE ++ KF +SDVWS+G+ ++E++++ + M+ + ++ Sbjct 811 PEAVQYRKFTSSSDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVINAID 856 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 + RLP P CP ++ LM +CW+ + RP FE ++ L + K Sbjct 857 QDYRLPPPPDCPTVLHLLMLDCWQKDRVQRPKFEQIVSALDKMIRK 902 Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 72/252 (29%), Positives = 121/252 (48%), Gaps = 22/252 (9%) Query 629 PGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 PG+ +E V +K L + D F AS+M Q H ++ + GV + ++VT Sbjct 659 PGK---REYTVAIKTLKSGYTDEQRREFLSEASIMGQFEHPNVIHLEGVVTKSRPVMIVT 715 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 E++E+G LD +LR++ G + + + + +A+ + YL + N VH ++ RNIL+ + Sbjct 716 EFMENGSLDSFLRQKEGQFSVLQLVGMLRGIAAGMRYLSDMNYVHRDLAARNILVNSNLV 775 Query 748 AE----GTSPFIK--LSDPGVGLGALSREERVERIP--WLAPECLPGGANSLSTAMDKWG 799 + G S F++ S+P GAL +IP W APE + +++ D W Sbjct 776 CKVSDFGLSRFLEDDASNPTY-TGALGC-----KIPIRWTAPEAVQ--YRKFTSSSDVWS 827 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQRP 857 +G + E+ GE P S + + + +RL P P CP L L C + QRP Sbjct 828 YGIVMWEVMSYGERPYWDMSNQDVINAIDQDYRLPPPPDCPTVLHLLMLDCWQKDRVQRP 887 Query 858 SFRTILRDLTRL 869 F I+ L ++ Sbjct 888 KFEQIVSALDKM 899 >sp|Q9UM73|ALK_HUMAN ALK tyrosine kinase receptor OS=Homo sapiens OX=9606 GN=ALK PE=1 SV=3 Length=1620 Score = 124 bits (312), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 104/350 (30%), Positives = 153/350 (44%), Gaps = 46/350 (13%) Query 855 QRPSFR-TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV-S 912 Q P ++ + LR T + +N + S SD ++ + IR LG G FG+V Sbjct 1074 QSPEYKLSKLRTSTIMTDYN-PNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYE 1132 Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972 ND + VAVK L C Q + E I+ H++I++ G Sbjct 1133 GQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGV------- 1185 Query 973 SLQ-----LVMEYVPLGSLRDYL----PR----HSIGLAQLLLFAQQICEGMAYLHAQHY 1019 SLQ +++E + G L+ +L PR S+ + LL A+ I G YL H+ Sbjct 1186 SLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHF 1245 Query 1020 IHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+AARN LL R+ KIGDFG+A+ + YYR PV W PE E Sbjct 1246 IHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRA-SYYRKGGCAMLPVKWMPPEAFMEG 1304 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 F +D WSFGV L+E+ + L + + + E + G R+ Sbjct 1305 IFTSKTDTWSFGVLLWEIFS--------------LGYMPYPSKSNQEVLEFVTSGGRMDP 1350 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 P CP VY +M CW+ + RP F ++ + +Y Q P V + Sbjct 1351 PKNCPGPVYRIMTQCWQHQPEDRPNFAIILERI-----EYCTQDPDVINT 1395 Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 85/310 (27%), Positives = 134/310 (43%), Gaps = 42/310 (14%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 +T ++S L V +K IT + LG G VYEG++ SG P +D PL Sbjct 1101 KTSSISDL--KEVPRKNITLIRGLGHGAFGEVYEGQV----SGMP-----NDPSPL---- 1145 Query 632 DRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 +V +K L + L F A ++S+ +H ++ GV ++ ++ E + Sbjct 1146 ------QVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELM 1199 Query 691 EHGPLDVWLR--RERGHVPMAWKMV----VAQQLASALSYLENKNLVHGNVCGRNILLAR 744 G L +LR R R P + M+ VA+ +A YLE + +H ++ RN LL Sbjct 1200 AGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLT- 1258 Query 745 LGLAEGTSPFIKLSDPGVG----LGALSREERVERIP--WLAPECLPGGANSLSTAMDKW 798 G K+ D G+ + R+ +P W+ PE G ++ D W Sbjct 1259 ---CPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGI--FTSKTDTW 1313 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQR 856 FG L EI G P S+S E F R+ P +CP + + +QC ++P R Sbjct 1314 SFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDR 1373 Query 857 PSFRTILRDL 866 P+F IL + Sbjct 1374 PNFAIILERI 1383 >sp|Q61084|M3K3_MOUSE Mitogen-activated protein kinase kinase kinase 3 OS=Mus musculus OX=10090 GN=Map3k3 PE=1 SV=1 Length=626 Score = 122 bits (307), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 82/239 (34%), Positives = 127/239 (53%), Gaps = 20/239 (8%) Query 868 RLQPHNLADVLTVN----PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923 RL+ + + LTV P S P + + L LG+G FG+V L CYD T Sbjct 334 RLRSADSENALTVQERNVPTKSPSAPINWRRGKL-----LGQGAFGRVYL-CYDV---DT 384 Query 924 GEMVAVKALKADCGP----QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979 G +A K ++ D + S + EI +L+ L HE I++Y GC D+ EK L + ME Sbjct 385 GRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKILTIFME 444 Query 980 YVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 Y+P GS++D L + ++ + + +QI EGM+YLH+ +HRD+ N+L D+ VK Sbjct 445 YMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVK 504 Query 1039 IGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 +GDFG +K + +R +P +W +PE + + +DVWS G T+ E+LT Sbjct 505 LGDFGASKRLQTICMSGTGIRSVTGTP-YWMSPEVISGEGYGRKADVWSLGCTVVEMLT 562 Score = 37.7 bits (86), Expect = 0.67, Method: Compositional matrix adjust. Identities = 47/193 (24%), Positives = 76/193 (39%), Gaps = 32/193 (17%) Query 632 DRGQELRVVLKVLDPSHHDIAL---AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT- 687 D G+EL DP + + A L+ + H + +G C+R ++T Sbjct 383 DTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYG-CLRDRAEKILTI 441 Query 688 --EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 EY+ G + L+ G + + +Q+ +SYL + +VH ++ G NIL Sbjct 442 FMEYMPGGSVKDQLK-AYGALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSA 500 Query 746 GLAEGTSPFIKLSDPGV----------GLGALSREERVERIP-WLAPECLPGGANSLSTA 794 G +KL D G G G S V P W++PE + G Sbjct 501 G-------NVKLGDFGASKRLQTICMSGTGIRS----VTGTPYWMSPEVISG--EGYGRK 547 Query 795 MDKWGFGATLLEI 807 D W G T++E+ Sbjct 548 ADVWSLGCTVVEM 560 >sp|P0DV84|ALK_CANLF ALK tyrosine kinase receptor OS=Canis lupus familiaris OX=9615 GN=ALK PE=3 SV=1 Length=1631 Score = 124 bits (312), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 104/350 (30%), Positives = 153/350 (44%), Gaps = 46/350 (13%) Query 855 QRPSFR-TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV-S 912 Q P ++ + LR T + +N + S SD ++ + IR LG G FG+V Sbjct 1089 QSPEYKLSKLRTSTIMTDYN-PNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYE 1147 Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972 +D + VAVK L C Q + E I+ H++I++ G Sbjct 1148 GQVSGVPSDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGV------- 1200 Query 973 SLQ-----LVMEYVPLGSLRDYL----PR----HSIGLAQLLLFAQQICEGMAYLHAQHY 1019 SLQ +++E + G L+ +L PR S+ + LL AQ I G YL H+ Sbjct 1201 SLQALPRFILLELMAGGDLKSFLRETRPRPNQPSSLAMLDLLHVAQDIACGCQYLEENHF 1260 Query 1020 IHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+AARN LL R+ KIGDFG+A+ + YYR PV W PE E Sbjct 1261 IHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRA-SYYRKGGCAMLPVKWMPPEAFMEG 1319 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 F +D WSFGV L+E+ + L + + + E + G R+ Sbjct 1320 IFTSKTDTWSFGVLLWEIFS--------------LGYMPYPSKSNQEVLEFVTSGGRMDP 1365 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 P CP VY +M CW+ + RP F ++ + +Y Q P V + Sbjct 1366 PKNCPGPVYRIMTQCWQHQPEDRPNFAIILERI-----EYCTQDPDVINT 1410 Score = 84.0 bits (206), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 86/310 (28%), Positives = 134/310 (43%), Gaps = 42/310 (14%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 +T ++S L V +K IT + LG G VYEG++ SG P D PL Sbjct 1116 KTSSISDLK--EVPRKNITLIRGLGHGAFGEVYEGQV----SGVP-----SDPSPL---- 1160 Query 632 DRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 +V +K L + L F A ++S+ +H ++ GV ++ ++ E + Sbjct 1161 ------QVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELM 1214 Query 691 EHGPLDVWLR--RERGHVPMAWKMV----VAQQLASALSYLENKNLVHGNVCGRNILLAR 744 G L +LR R R + P + M+ VAQ +A YLE + +H ++ RN LL Sbjct 1215 AGGDLKSFLRETRPRPNQPSSLAMLDLLHVAQDIACGCQYLEENHFIHRDIAARNCLLT- 1273 Query 745 LGLAEGTSPFIKLSDPGVG----LGALSREERVERIP--WLAPECLPGGANSLSTAMDKW 798 G K+ D G+ + R+ +P W+ PE G ++ D W Sbjct 1274 ---CPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGI--FTSKTDTW 1328 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQR 856 FG L EI G P S+S E F R+ P +CP + + +QC ++P R Sbjct 1329 SFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDR 1388 Query 857 PSFRTILRDL 866 P+F IL + Sbjct 1389 PNFAIILERI 1398 >sp|P80192|M3K9_HUMAN Mitogen-activated protein kinase kinase kinase 9 OS=Homo sapiens OX=9606 GN=MAP3K9 PE=1 SV=3 Length=1104 Score = 124 bits (311), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 99/297 (33%), Positives = 145/297 (49%), Gaps = 43/297 (14%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG---PQHRSGWKQEI 948 F + L++I +G G FGKV + G+ VAVKA + D Q +QE Sbjct 141 FAELTLEEI--IGIGGFGKVYRAFW------IGDEVAVKAARHDPDEDISQTIENVRQEA 192 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008 + L H +II +G C E +L LVME+ G L L I L+ +A QI Sbjct 193 KLFAMLKHPNIIALRGVC--LKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIA 250 Query 1009 EGMAYLHAQHY---IHRDLAARNVLL----DN----DRLVKIGDFGLAKAVPEGHEYYRV 1057 GM YLH + IHRDL + N+L+ +N ++++KI DFGLA+ E H ++ Sbjct 251 RGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLAR---EWHRTTKM 307 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 G W APE ++ F SDVWS+GV L+ELLT P + ++ + +A G Sbjct 308 SAAGT--YAWMAPEVIRASMFSKGSDVWSYGVLLWELLTG-----EVPFRGIDGLAVAYG 360 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + + +L LP P CP LM++CW + RP+F N++ L T+ E Sbjct 361 ----VAMNKLA-----LPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNILDQLTTIEE 408 Score = 71.6 bits (174), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 72/254 (28%), Positives = 119/254 (47%), Gaps = 28/254 (11%) Query 634 GQELRVVLKVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 G E+ V DP DI+ + A L + + H ++ + GVC++ P +V E+ Sbjct 165 GDEVAVKAARHDPDE-DISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFA 223 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV---HGNVCGRNIL-LARLG 746 GPL+ L +R +P + A Q+A ++YL ++ +V H ++ NIL L ++ Sbjct 224 RGGPLNRVLSGKR--IPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVE 281 Query 747 LAEGTSPFIKLSDPGVGLGALSRE-ERVERIP------WLAPECLPGGANSLSTAMDKWG 799 + ++ +K++D G L+RE R ++ W+APE + A+ S D W Sbjct 282 NGDLSNKILKITDFG-----LAREWHRTTKMSAAGTYAWMAPEVI--RASMFSKGSDVWS 334 Query 800 FGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQR 856 +G L E+ GE P + + + LP PS CP+ A L C +P R Sbjct 335 YGVLLWEL-LTGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSR 393 Query 857 PSFRTILRDLTRLQ 870 PSF IL LT ++ Sbjct 394 PSFTNILDQLTTIE 407 >sp|O22558|STY8_ARATH Serine/threonine-protein kinase STY8 OS=Arabidopsis thaliana OX=3702 GN=STY8 PE=1 SV=2 Length=546 Score = 120 bits (302), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 83/281 (30%), Positives = 139/281 (49%), Gaps = 33/281 (12%) Query 897 LKKIRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRT 953 LK + + G +G + YC + VA+K LK D + + QE+ I+R Sbjct 286 LKIEKKVASGSYGDLHRGTYC--------SQEVAIKFLKPDRVNNEMLREFSQEVFIMRK 337 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGM 1011 + H++++++ G C +L +V E++ GS+ D+L + + L LL A + +GM Sbjct 338 VRHKNVVQFLGAC--TRSPTLCIVTEFMARGSIYDFLHKQKCAFKLQTLLKVALDVAKGM 395 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 +YLH + IHRDL N+L+D LVK+ DFG+A+ E V W APE Sbjct 396 SYLHQNNIIHRDLKTANLLMDEHGLVKVADFGVARVQIESG----VMTAETGTYRWMAPE 451 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 ++ + + +DV+S+ + L+ELLT P FL + A G ++++G Sbjct 452 VIEHKPYNHKADVFSYAIVLWELLTG-----DIPYAFLTPLQAAVG---------VVQKG 497 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 R P K +V L++ CW + RP FE +I +L+ + Sbjct 498 LRPKIPKKTHPKVKGLLERCWHQDPEQRPLFEEIIEMLQQI 538 Score = 73.6 bits (179), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 59/241 (24%), Positives = 112/241 (46%), Gaps = 22/241 (9%) Query 639 VVLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K L P ++++ F + +M +V H ++ G C R P +VTE++ G + Sbjct 310 VAIKFLKPDRVNNEMLREFSQEVFIMRKVRHKNVVQFLGACTRSPTLCIVTEFMARGSIY 369 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L +++ + + VA +A +SYL N++H ++ N+L+ GL +K Sbjct 370 DFLHKQKCAFKLQTLLKVALDVAKGMSYLHQNNIIHRDLKTANLLMDEHGL-------VK 422 Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D GV G ++ E R W+APE + + D + + L E+ G Sbjct 423 VADFGVARVQIESGVMTAETGTYR--WMAPEVIEH--KPYNHKADVFSYAIVLWEL-LTG 477 Query 812 EAPLQSRSPSEKE-HFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + P +P + Q+ R +P+ + P++ L +C +P QRP F I+ L + Sbjct 478 DIPYAFLTPLQAAVGVVQKGLRPKIPKKTHPKVKGLLERCWHQDPEQRPLFEEIIEMLQQ 537 Query 869 L 869 + Sbjct 538 I 538 >sp|Q66L42|M3K10_MOUSE Mitogen-activated protein kinase kinase kinase 10 OS=Mus musculus OX=10090 GN=Map3k10 PE=1 SV=2 Length=940 Score = 122 bits (307), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 100/306 (33%), Positives = 149/306 (49%), Gaps = 47/306 (15%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW-----KQ 946 FH+ L++I +G G FGKV + GE VAVKA + D P+ +Q Sbjct 95 FHELQLEEI--IGVGGFGKVYRAVW------RGEEVAVKAARLD--PERDPAVTAEQVRQ 144 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006 E + L H +II +G C +L LVMEY G+L L + L+ +A Q Sbjct 145 EARLFGALQHPNIIALRGAC--LSPPNLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQ 202 Query 1007 ICEGMAYLHAQH---YIHRDLAARNVLL----DN----DRLVKIGDFGLAKAVPEGHEYY 1055 + GM YLH IHRDL + N+L+ +N D ++KI DFGLA+ E H+ Sbjct 203 VARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAR---EWHKTT 259 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 ++ G W APE ++ F +SDVWSFGV L+ELLT P + ++ + +A Sbjct 260 KMSAAGT--YAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTG-----EVPYREIDALAVA 312 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 G + + +LT LP P CP L++ CW+ + RP F +++ L+ + + Sbjct 313 YG-VAMNKLT--------LPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKQLEVIEQS 363 Query 1176 YQGQAP 1181 Q P Sbjct 364 ALFQMP 369 Score = 65.1 bits (157), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 70/250 (28%), Positives = 108/250 (43%), Gaps = 26/250 (10%) Query 633 RGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 RG+E+ V LDP A + A L + H ++ + G C+ P +V EY Sbjct 118 RGEEVAVKAARLDPERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSPPNLCLVMEYA 177 Query 691 EHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745 G L L RR HV + W A Q+A ++YL N ++H ++ NIL+ Sbjct 178 RGGALSRVLAGRRVPPHVLVNW----AVQVARGMNYLHNDAPVPIIHRDLKSINILILEA 233 Query 746 ----GLAEGTSPFIKLSDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 LA+ +K++D G+ ++ W+APE + + S + D W Sbjct 234 IENHNLADTV---LKITDFGLAREWHKTTKMSAAGTYAWMAPEVI--RLSLFSKSSDVWS 288 Query 800 FGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQR 856 FG L E+ GE P + + + LP PS CP+ A L +C +P R Sbjct 289 FGVLLWEL-LTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGR 347 Query 857 PSFRTILRDL 866 P F +IL+ L Sbjct 348 PDFGSILKQL 357 >sp|P04048|KIT_FSVHZ Tyrosine-protein kinase transforming protein kit OS=Feline sarcoma virus (strain Hardy-Zuckerman 4) OX=11777 GN=V-KIT PE=3 SV=1 Length=370 Score = 117 bits (293), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 61/173 (35%), Positives = 99/173 (57%), Gaps = 14/173 (8%) Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ + Sbjct 210 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 268 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 PV W APE + + + SDVWS+G+ L+EL + SS P G Sbjct 269 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 315 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 + ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++ K Sbjct 316 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQKNK 368 Score = 50.8 bits (120), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 39/168 (23%), Positives = 74/168 (44%), Gaps = 22/168 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A +++L +KN +H ++ RNILL K+ D G+ + V + Sbjct 213 QVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIKNDSNYVVKG 265 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--- 827 + W+APE + + + D W +G L E+ G +P K FY Sbjct 266 NARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYKMI 321 Query 828 QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 + R+ PE + ++ + C +P +RP+F+ I++ + + + N Sbjct 322 KEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQKNKN 369 Score = 37.4 bits (85), Expect = 0.79, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689 + V +K+L PS H E +LMS++ +H ++ + G C G +++TEY Sbjct 56 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEY 110 Query 690 VEHGPLDVWLRRER 703 +G L +LRR+R Sbjct 111 CCYGDLLNFLRRKR 124 >sp|P54753|EPHB3_HUMAN Ephrin type-B receptor 3 OS=Homo sapiens OX=9606 GN=EPHB3 PE=1 SV=2 Length=998 Score = 122 bits (307), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 78/273 (29%), Positives = 135/273 (49%), Gaps = 25/273 (9%) Query 903 LGEGHFGKVSLYCYDPTND-GTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G FG+V C G E+ VA+K LK + R + E I+ H +II Sbjct 639 IGAGEFGEV---CRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNII 695 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018 + +G + + ++ E++ +L +L + + QL+ + I GM YL + Sbjct 696 RLEGVVTKS--RPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMN 753 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE--GHEYYRVREDGDSPVFWYAPECLKEY 1076 Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G P+ W APE + Sbjct 754 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYR 813 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 KF ASDVWS+G+ ++E++++ + M+ + +E+ RLP Sbjct 814 KFTSASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVINAVEQDYRLPP 859 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P CP ++ LM +CW + + RP F ++ L Sbjct 860 PMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTL 892 Score = 83.6 bits (205), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 68/248 (27%), Positives = 115/248 (46%), Gaps = 14/248 (6%) Query 629 PGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 PGR +E+ V +K L + + F AS+M Q H ++ + GV + +++T Sbjct 655 PGR---REVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILT 711 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 E++E+ LD +LR G + + + + +A+ + YL N VH ++ RNIL+ + Sbjct 712 EFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLV 771 Query 748 AE----GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 + G S F++ DP S ++ I W APE + ++A D W +G Sbjct 772 CKVSDFGLSRFLE-DDPSDPTYTSSLGGKIP-IRWTAPEAI--AYRKFTSASDVWSYGIV 827 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRT 861 + E+ GE P S + + ++ +RLP P CP L L C + RP F Sbjct 828 MWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQ 887 Query 862 ILRDLTRL 869 I+ L +L Sbjct 888 IVNTLDKL 895 >sp|Q08881|ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=Homo sapiens OX=9606 GN=ITK PE=1 SV=1 Length=620 Score = 121 bits (303), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 82/280 (29%), Positives = 129/280 (46%), Gaps = 27/280 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L ++++G G FG V L + + VA+K ++ G + +E +++ L H Sbjct 363 LTFVQEIGSGQFGLVHLGYW-----LNKDKVAIKTIRE--GAMSEEDFIEEAEVMMKLSH 415 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYL 1014 +++ G C +Q + LV E++ G L DYL R LL +CEGMAYL Sbjct 416 PKLVQLYGVCLEQA--PICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYL 473 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDLAARN L+ ++++K+ DFG+ + V + Y PV W +PE Sbjct 474 EEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQ--YTSSTGTKFPVKWASPEVFS 531 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 ++ SDVWSFGV ++E+ + I + + E + G RL Sbjct 532 FSRYSSKSDVWSFGVLMWEVFSEGK--------------IPYENRSNSEVVEDISTGFRL 577 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 +P VY +M +CW+ RP F L+ L + E Sbjct 578 YKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAE 617 Score = 90.5 bits (223), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 61/227 (27%), Positives = 104/227 (46%), Gaps = 16/227 (7%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F E A +M ++SH L ++GVC+ +V E++EHG L +LR +RG + + Sbjct 403 FIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGM 462 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + ++YLE ++H ++ RN L+ G + IK+SD G+ L + Sbjct 463 CLDVCEGMAYLEEACVIHRDLAARNCLV-------GENQVIKVSDFGMTRFVLDDQYTSS 515 Query 775 R-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 + W +PE + S+ D W FG + E+ +G+ P ++RS SE Sbjct 516 TGTKFPVKWASPEVF--SFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDIST 573 Query 830 QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 RL +P + + + + C P RP+F +LR L + L Sbjct 574 GFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAESGL 620 >sp|Q3U1V8|M3K9_MOUSE Mitogen-activated protein kinase kinase kinase 9 OS=Mus musculus OX=10090 GN=Map3k9 PE=2 SV=2 Length=1077 Score = 122 bits (306), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 98/297 (33%), Positives = 145/297 (49%), Gaps = 43/297 (14%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG---PQHRSGWKQEI 948 F + L++I +G G FGKV + G+ VAVKA + D Q +QE Sbjct 134 FAELTLEEI--IGIGGFGKVYRAFW------AGDEVAVKAARHDPDEDISQTIENVRQEA 185 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008 + L H +II +G C E +L LVME+ G L L I L+ +A QI Sbjct 186 KLFAMLKHPNIIALRGVC--LKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIA 243 Query 1009 EGMAYLHAQHY---IHRDLAARNVLL----DN----DRLVKIGDFGLAKAVPEGHEYYRV 1057 GM YLH + IHRDL + N+L+ +N ++++KI DFGLA+ E H ++ Sbjct 244 RGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLAR---EWHRTTKM 300 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 G W APE ++ F SDVWS+GV L+ELLT P + ++ + +A G Sbjct 301 SAAGT--YAWMAPEVIRASMFSKGSDVWSYGVLLWELLTG-----EVPFRGIDGLAVAYG 353 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + + +L LP P CP LM++CW + RP+F +++ L T+ E Sbjct 354 ----VAMNKLA-----LPIPSTCPEPFAKLMEDCWNPDPHSRPSFTSILDQLTTIEE 401 Score = 72.0 bits (175), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 72/254 (28%), Positives = 120/254 (47%), Gaps = 28/254 (11%) Query 634 GQELRVVLKVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 G E+ V DP DI+ + A L + + H ++ + GVC++ P +V E+ Sbjct 158 GDEVAVKAARHDPDE-DISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFA 216 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV---HGNVCGRNIL-LARLG 746 GPL+ L +R +P + A Q+A ++YL ++ +V H ++ NIL L ++ Sbjct 217 RGGPLNRVLSGKR--IPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVE 274 Query 747 LAEGTSPFIKLSDPGVGLGALSRE-ERVERIP------WLAPECLPGGANSLSTAMDKWG 799 + ++ +K++D G L+RE R ++ W+APE + A+ S D W Sbjct 275 NGDLSNKILKITDFG-----LAREWHRTTKMSAAGTYAWMAPEVI--RASMFSKGSDVWS 327 Query 800 FGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQR 856 +G L E+ GE P + + + LP PS CP+ A L C +P R Sbjct 328 YGVLLWEL-LTGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSR 386 Query 857 PSFRTILRDLTRLQ 870 PSF +IL LT ++ Sbjct 387 PSFTSILDQLTTIE 400 >sp|P54754|EPHB3_MOUSE Ephrin type-B receptor 3 OS=Mus musculus OX=10090 GN=Ephb3 PE=1 SV=2 Length=993 Score = 122 bits (306), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 75/269 (28%), Positives = 129/269 (48%), Gaps = 25/269 (9%) Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 VA+K LK + R + E I+ H +II+ +G + + ++ E++ + Sbjct 656 FVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMILTEFMENCA 713 Query 986 LRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 L +L + + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFG Sbjct 714 LDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFG 773 Query 1044 LAKAVPE--GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 L++ + + Y G P+ W APE + KF ASDVWS+G+ ++E++++ + Sbjct 774 LSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGER- 832 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 M+ + +E+ RLP P CP ++ LM +CW + + RP Sbjct 833 -------------PYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPK 879 Query 1162 FENLIPIL-----KTVHEKYQGQAPSVFS 1185 F ++ L K APS S Sbjct 880 FSQIVNTLDKLIRNAASLKVTASAPSGMS 908 Score = 84.7 bits (208), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 72/269 (27%), Positives = 124/269 (46%), Gaps = 14/269 (5%) Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 +PGR +E+ V +K L + + F AS+M Q H ++ + GV + +++ Sbjct 649 LPGR---REVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIL 705 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TE++E+ LD +LR G + + + + +A+ + YL N VH ++ RNIL+ Sbjct 706 TEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNL 765 Query 747 LAE----GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 + + G S F++ DP S ++ I W APE + ++A D W +G Sbjct 766 VCKVSDFGLSRFLE-DDPSDPTYTSSLGGKIP-IRWTAPEAI--AYRKFTSASDVWSYGI 821 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFR 860 + E+ GE P S + + ++ +RLP P CP L L C + RP F Sbjct 822 VMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFS 881 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDP 889 I+ L +L + + +T + S S P Sbjct 882 QIVNTLDKLIRNAASLKVTASAPSGMSQP 910 >sp|D3ZG83|M3K10_RAT Mitogen-activated protein kinase kinase kinase 10 OS=Rattus norvegicus OX=10116 GN=Map3k10 PE=1 SV=3 Length=940 Score = 122 bits (305), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 100/306 (33%), Positives = 149/306 (49%), Gaps = 47/306 (15%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW-----KQ 946 FH+ L++I +G G FGKV + GE VAVKA + D P+ +Q Sbjct 95 FHELQLEEI--IGVGGFGKVYRALW------RGEEVAVKAARLD--PERDPAVTAEQVRQ 144 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006 E + L H +II +G C +L LVMEY G+L L + L+ +A Q Sbjct 145 EARLFGALQHPNIIALRGAC--LSPPNLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQ 202 Query 1007 ICEGMAYLHAQH---YIHRDLAARNVLL----DN----DRLVKIGDFGLAKAVPEGHEYY 1055 + GM YLH IHRDL + N+L+ +N D ++KI DFGLA+ E H+ Sbjct 203 VARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAR---EWHKTT 259 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 ++ G W APE ++ F +SDVWSFGV L+ELLT P + ++ + +A Sbjct 260 KMSAAGT--YAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTG-----EVPYREIDALAVA 312 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 G + + +LT LP P CP L++ CW+ + RP F +++ L+ + + Sbjct 313 YG-VAMNKLT--------LPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKQLEVIEQS 363 Query 1176 YQGQAP 1181 Q P Sbjct 364 ALFQMP 369 Score = 65.1 bits (157), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 70/250 (28%), Positives = 108/250 (43%), Gaps = 26/250 (10%) Query 633 RGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 RG+E+ V LDP A + A L + H ++ + G C+ P +V EY Sbjct 118 RGEEVAVKAARLDPERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSPPNLCLVMEYA 177 Query 691 EHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745 G L L RR HV + W A Q+A ++YL N ++H ++ NIL+ Sbjct 178 RGGALSRVLAGRRVPPHVLVNW----AVQVARGMNYLHNDAPVPIIHRDLKSINILILEA 233 Query 746 ----GLAEGTSPFIKLSDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 LA+ +K++D G+ ++ W+APE + + S + D W Sbjct 234 IENHNLADTV---LKITDFGLAREWHKTTKMSAAGTYAWMAPEVI--RLSLFSKSSDVWS 288 Query 800 FGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQR 856 FG L E+ GE P + + + LP PS CP+ A L +C +P R Sbjct 289 FGVLLWEL-LTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGR 347 Query 857 PSFRTILRDL 866 P F +IL+ L Sbjct 348 PDFGSILKQL 357 >sp|Q07498|EPHB3_CHICK Ephrin type-B receptor 3 (Fragment) OS=Gallus gallus OX=9031 GN=EPHB3 PE=2 SV=1 Length=988 Score = 122 bits (305), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 78/273 (29%), Positives = 134/273 (49%), Gaps = 25/273 (9%) Query 903 LGEGHFGKVSLYCYDPTN-DGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G FG+V C G E+ VA+K LK + R + E I+ H +II Sbjct 629 IGAGEFGEV---CRGRLKLPGRREIFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNII 685 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018 +G + + ++ E++ +L +L + + QL+ + I GM YL + Sbjct 686 HLEGVVTKS--RPVMIITEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMN 743 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE--GHEYYRVREDGDSPVFWYAPECLKEY 1076 Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G P+ W APE + Sbjct 744 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPADPTYTSSLGGKIPIRWTAPEAIAYR 803 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 KF ASDVWS+G+ ++E++++ + M+ + +E+ RLP Sbjct 804 KFTSASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVINAVEQDYRLPP 849 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P CP ++ LM +CW + + RP F ++ L Sbjct 850 PMDCPTALHQLMLDCWVRDRNLRPKFAQIVNTL 882 Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 68/249 (27%), Positives = 116/249 (47%), Gaps = 14/249 (6%) Query 628 VPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 +PGR +E+ V +K L + + F AS+M Q H ++ + GV + +++ Sbjct 644 LPGR---REIFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIHLEGVVTKSRPVMII 700 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TE++E+ LD +LR G + + + + +A+ + YL N VH ++ RNIL+ Sbjct 701 TEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNL 760 Query 747 LAE----GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 + + G S F++ DP S ++ I W APE + ++A D W +G Sbjct 761 VCKVSDFGLSRFLE-DDPADPTYTSSLGGKIP-IRWTAPEAI--AYRKFTSASDVWSYGI 816 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFR 860 + E+ GE P S + + ++ +RLP P CP L L C + RP F Sbjct 817 VMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFA 876 Query 861 TILRDLTRL 869 I+ L +L Sbjct 877 QIVNTLDKL 885 >sp|Q21038|VER3_CAEEL Tyrosine-protein kinase receptor ver-3 OS=Caenorhabditis elegans OX=6239 GN=ver-3 PE=2 SV=1 Length=1227 Score = 122 bits (305), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 66/176 (38%), Positives = 91/176 (52%), Gaps = 17/176 (10%) Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + LL QI +GMA+L +HRDLA RNVL+ ++V+I DFGL+K YYR Sbjct 1005 SDLLSIGLQIAKGMAWLADVPCVHRDLACRNVLITKTKIVRIADFGLSKK-HTNKTYYRT 1063 Query 1058 REDGDS--PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 ++ D+ PV W EC++E+KF SDVWSFG+ LYE+ T L G Sbjct 1064 KKSKDTPLPVRWMPLECIEEFKFTQKSDVWSFGICLYEIFT--------------LGGTP 1109 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + E + G R +P+ C E+Y LMK CW+ RPTF + I + Sbjct 1110 YPNCDTFNVIEFIRNGNRNKQPEYCHDEIYELMKVCWQFNPKDRPTFNDCITFFEN 1165 Score = 42.0 bits (97), Expect = 0.039, Method: Compositional matrix adjust. Identities = 34/159 (21%), Positives = 67/159 (42%), Gaps = 19/159 (12%) Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--- 768 + + Q+A +++L + VH ++ RN+L+ + + ++++D G+ + Sbjct 1008 LSIGLQIAKGMAWLADVPCVHRDLACRNVLITK-------TKIVRIADFGLSKKHTNKTY 1060 Query 769 -REERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 R ++ + P W+ EC+ + D W FG L EI G P + Sbjct 1061 YRTKKSKDTPLPVRWMPLECIEEF--KFTQKSDVWSFGICLYEIFTLGGTPYPNCDTFNV 1118 Query 824 EHFYQRQHRLPEPS-C-PQLATLTSQCLTYEPTQRPSFR 860 F + +R +P C ++ L C + P RP+F Sbjct 1119 IEFIRNGNRNKQPEYCHDEIYELMKVCWQFNPKDRPTFN 1157 >sp|Q17833|OLD1_CAEEL Tyrosine-protein kinase receptor old-1 OS=Caenorhabditis elegans OX=6239 GN=old-1 PE=2 SV=3 Length=502 Score = 119 bits (297), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 79/228 (35%), Positives = 117/228 (51%), Gaps = 29/228 (13%) Query 970 GEKSLQLVMEYVPLGSLRDYL----------------PRHSIGLAQLLLFAQQICEGMAY 1013 GE+ + +V E+V G L +L + S+ L LL FA QI +GM Y Sbjct 253 GERKM-IVSEFVENGDLLSFLRDNRIYFTNDQWTLETEQDSLSLVDLLSFAFQIAKGMEY 311 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE-DGDSPVFWYAPEC 1072 L +HRDLA RNVL+ +R+++I DFGLA+ + +YY+ + D P+ W APE Sbjct 312 LIHVPCVHRDLALRNVLIKKNRIIRIADFGLARR-HKNKDYYKTQSVDTPLPIHWMAPES 370 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + F SDVWS+GV LYEL + +SP + +I Q + L G+ Sbjct 371 IDKLLFTQKSDVWSYGVCLYELFS---LGKSP---YENVIKYDQRDFYWKYVLSYLNEGK 424 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI----LKTVHEKY 1176 RL +P E+Y++MK CW+ + + R TF + I LKT +Y Sbjct 425 RLAQPAHADAEIYNVMKLCWDLDMNSRTTFLDCIEFFEKELKTTSNEY 472 Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 49/221 (22%), Positives = 95/221 (43%), Gaps = 41/221 (19%) Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM-AWKMVVAQ------------ 716 LA V G+ G ++V+E+VE+G L +LR R + W + Q Sbjct 244 LALVGGITF-GERKMIVSEFVENGDLLSFLRDNRIYFTNDQWTLETEQDSLSLVDLLSFA 302 Query 717 -QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE----E 771 Q+A + YL + VH ++ RN+L+ + + I+++D G+ +++ + Sbjct 303 FQIAKGMEYLIHVPCVHRDLALRNVLIKK-------NRIIRIADFGLARRHKNKDYYKTQ 355 Query 772 RVER---IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 V+ I W+APE + + D W +G L E+ G++P ++ ++ FY Sbjct 356 SVDTPLPIHWMAPESIDKLL--FTQKSDVWSYGVCLYELFSLGKSPYENVIKYDQRDFYW 413 Query 829 RQ--------HRLPEP--SCPQLATLTSQCLTYEPTQRPSF 859 + RL +P + ++ + C + R +F Sbjct 414 KYVLSYLNEGKRLAQPAHADAEIYNVMKLCWDLDMNSRTTF 454 >sp|F4JTP5|STY46_ARATH Serine/threonine-protein kinase STY46 OS=Arabidopsis thaliana OX=3702 GN=STY46 PE=1 SV=1 Length=575 Score = 119 bits (299), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 81/283 (29%), Positives = 142/283 (50%), Gaps = 33/283 (12%) Query 895 RYLKKIRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDIL 951 ++LK + G +G + YC + VA+K LK + + QE+ I+ Sbjct 288 KHLKFGHKIASGSYGDLYKGTYC--------SQEVAIKVLKPERLDSDLEKEFAQEVFIM 339 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICE 1009 R + H++++++ G C L +V E++P GS+ DYL + L L A IC+ Sbjct 340 RKVRHKNVVQFIGAC--TKPPHLCIVTEFMPGGSVYDYLHKQKGVFKLPTLFKVAIDICK 397 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 GM+YLH + IHRDL A N+L+D + +VK+ DFG+A+ + E G W A Sbjct 398 GMSYLHQNNIIHRDLKAANLLMDENEVVKVADFGVARV--KAQTGVMTAETG--TYRWMA 453 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE ++ + + +DV+S+G+ L+ELLT P +++ + A G +++ Sbjct 454 PEVIEHKPYDHKADVFSYGIVLWELLT-----GKLPYEYMTPLQAAVG---------VVQ 499 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +G R P ++ L++ WE +++ RP F +I L+ + Sbjct 500 KGLRPTIPKNTHPKLAELLERLWEHDSTQRPDFSEIIEQLQEI 542 Score = 75.9 bits (185), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 60/241 (25%), Positives = 110/241 (46%), Gaps = 22/241 (9%) Query 639 VVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +KVL P D+ F + +M +V H ++ G C + P +VTE++ G + Sbjct 314 VAIKVLKPERLDSDLEKEFAQEVFIMRKVRHKNVVQFIGACTKPPHLCIVTEFMPGGSVY 373 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L +++G + VA + +SYL N++H ++ N+L+ + +K Sbjct 374 DYLHKQKGVFKLPTLFKVAIDICKGMSYLHQNNIIHRDLKAANLLM-------DENEVVK 426 Query 757 LSDPGVG-----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D GV G ++ E R W+APE + D + +G L E+ G Sbjct 427 VADFGVARVKAQTGVMTAETGTYR--WMAPEVIE--HKPYDHKADVFSYGIVLWEL-LTG 481 Query 812 EAPLQSRSPSEKE-HFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + P + +P + Q+ R +P+ + P+LA L + ++ TQRP F I+ L Sbjct 482 KLPYEYMTPLQAAVGVVQKGLRPTIPKNTHPKLAELLERLWEHDSTQRPDFSEIIEQLQE 541 Query 869 L 869 + Sbjct 542 I 542 >sp|P34892|KIN16_CAEEL Receptor-like tyrosine-protein kinase kin-16 OS=Caenorhabditis elegans OX=6239 GN=kin-16 PE=2 SV=1 Length=495 Score = 118 bits (296), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 68/184 (37%), Positives = 93/184 (51%), Gaps = 20/184 (11%) Query 988 DYLPRHSIG---LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 DY+ + S+ + LL F QI GM YL + +HRDLA RNVLL ++ ++I DFG+ Sbjct 283 DYVIKESLDSLTTSDLLSFGLQIANGMQYLASIPMVHRDLALRNVLLKKNKTIRIADFGM 342 Query 1045 AKAVPEGHEYY--RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 A+ E YY + +D PV W +PE KF SDVWSFG+ LYE+ T Sbjct 343 ART-HENKSYYIPQKTKDAPVPVRWMSPEAFDTMKFTEKSDVWSFGICLYEIFT------ 395 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 L + + R+ E + G R P+P C E+Y LMK CW + RP F Sbjct 396 --------LGQLPYPDVPSERIYEYMHSGRRCPQPQHCHVELYDLMKLCWHEKPELRPNF 447 Query 1163 ENLI 1166 N + Sbjct 448 SNCV 451 Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 44/157 (28%), Positives = 70/157 (45%), Gaps = 27/157 (17%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI 776 Q+A+ + YL + +VH ++ RN+LL + + I+++D G+ A + E + I Sbjct 304 QIANGMQYLASIPMVHRDLALRNVLLKK-------NKTIRIADFGM---ARTHENKSYYI 353 Query 777 P-----------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 P W++PE + D W FG L EI G+ P PSE+ + Sbjct 354 PQKTKDAPVPVRWMSPEAF--DTMKFTEKSDVWSFGICLYEIFTLGQLPYPD-VPSERIY 410 Query 826 FYQRQ-HRLPEPS-C-PQLATLTSQCLTYEPTQRPSF 859 Y R P+P C +L L C +P RP+F Sbjct 411 EYMHSGRRCPQPQHCHVELYDLMKLCWHEKPELRPNF 447 >sp|Q5XF79|PBL18_ARATH Probable serine/threonine-protein kinase PBL18 OS=Arabidopsis thaliana OX=3702 GN=PBL18 PE=2 SV=1 Length=387 Score = 116 bits (290), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 95/295 (32%), Positives = 136/295 (46%), Gaps = 32/295 (11%) Query 895 RYLKKIRDLGEGHFGKV-----SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 R K +GEG FG V P+ G+G +VAVK LK++ G Q W E+ Sbjct 82 RNFKPNSMIGEGGFGCVYKGWIGERSLSPSKPGSGMVVAVKKLKSE-GFQGHKEWLTEVH 140 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQ 1006 L L+H +++K G C +GEK L LV EY+P GSL ++L R I + A Sbjct 141 YLGRLHHMNLVKLIGYCL-EGEKRL-LVYEYMPKGSLENHLFRRGAEPIPWKTRMKVAFS 198 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G+++LH I+RD A N+LLD D K+ DFGLAKA P G + V Sbjct 199 AARGLSFLHEAKVIYRDFKASNILLDVDFNAKLSDFGLAKAGPTGDRTH-VTTQVIGTQG 257 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG--------- 1117 + APE + + SDV+SFGV L ELL+ PT +G+ + Sbjct 258 YAAPEYIATGRLTSKSDVYSFGVVLLELLS------GRPTLDKSKVGVERNLVDWAIPYL 311 Query 1118 --QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + V R+ + G+ P K C ++ C TE RP +++ L+ Sbjct 312 VDRRKVFRIMDTKLGGQ---YPHKGACAAANIALRCLNTEPKLRPDMADVLSTLQ 363 Score = 55.1 bits (131), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 58/235 (25%), Positives = 97/235 (41%), Gaps = 36/235 (15%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK--MVVAQQLA 719 + ++ H +L + G C+ G + ++V EY+ G L+ L R RG P+ WK M VA A Sbjct 142 LGRLHHMNLVKLIGYCLEGEKRLLVYEYMPKGSLENHLFR-RGAEPIPWKTRMKVAFSAA 200 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERV 773 LS+L +++ + NILL KLSD G+ + + + + Sbjct 201 RGLSFLHEAKVIYRDFKASNILL-------DVDFNAKLSDFGLAKAGPTGDRTHVTTQVI 253 Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-------HF 826 + APE + G L++ D + FG LLE+ +S+ E+ + Sbjct 254 GTQGYAAPEYIATG--RLTSKSDVYSFGVVLLELLSGRPTLDKSKVGVERNLVDWAIPYL 311 Query 827 YQRQH-----------RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 R+ + P A + +CL EP RP +L L +L+ Sbjct 312 VDRRKVFRIMDTKLGGQYPHKGACAAANIALRCLNTEPKLRPDMADVLSTLQQLE 366 >sp|Q02779|M3K10_HUMAN Mitogen-activated protein kinase kinase kinase 10 OS=Homo sapiens OX=9606 GN=MAP3K10 PE=1 SV=3 Length=954 Score = 120 bits (301), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 100/306 (33%), Positives = 148/306 (48%), Gaps = 47/306 (15%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK-----Q 946 FH+ L++I +G G FGKV + GE VAVKA + D P+ Q Sbjct 95 FHELQLEEI--IGVGGFGKVYRALW------RGEEVAVKAARLD--PEKDPAVTAEQVCQ 144 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006 E + L H +II +G C + L LVMEY G+L L + L+ +A Q Sbjct 145 EARLFGALQHPNIIALRGACLNP--PHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQ 202 Query 1007 ICEGMAYLHAQH---YIHRDLAARNVLL----DN----DRLVKIGDFGLAKAVPEGHEYY 1055 + GM YLH IHRDL + N+L+ +N D ++KI DFGLA+ E H+ Sbjct 203 VARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAR---EWHKTT 259 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 ++ G W APE ++ F +SDVWSFGV L+ELLT P + ++ + +A Sbjct 260 KMSAAGT--YAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTG-----EVPYREIDALAVA 312 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 G + + +LT LP P CP L++ CW+ + RP F +++ L+ + + Sbjct 313 YG-VAMNKLT--------LPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQS 363 Query 1176 YQGQAP 1181 Q P Sbjct 364 ALFQMP 369 Score = 63.9 bits (154), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 70/254 (28%), Positives = 110/254 (43%), Gaps = 26/254 (10%) Query 633 RGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 RG+E+ V LDP A + A L + H ++ + G C+ P +V EY Sbjct 118 RGEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRGACLNPPHLCLVMEYA 177 Query 691 EHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745 G L L RR HV + W A Q+A ++YL N ++H ++ NIL+ Sbjct 178 RGGALSRVLAGRRVPPHVLVNW----AVQVARGMNYLHNDAPVPIIHRDLKSINILILEA 233 Query 746 ----GLAEGTSPFIKLSDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 LA+ +K++D G+ ++ W+APE + + S + D W Sbjct 234 IENHNLADTV---LKITDFGLAREWHKTTKMSAAGTYAWMAPEVI--RLSLFSKSSDVWS 288 Query 800 FGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQR 856 FG L E+ GE P + + + LP PS CP+ A L +C +P R Sbjct 289 FGVLLWEL-LTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGR 347 Query 857 PSFRTILRDLTRLQ 870 P F +IL+ L ++ Sbjct 348 PDFGSILKRLEVIE 361 >sp|Q01974|ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 OS=Homo sapiens OX=9606 GN=ROR2 PE=1 SV=2 Length=943 Score = 120 bits (301), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 82/287 (29%), Positives = 130/287 (45%), Gaps = 35/287 (12%) Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 ++ + +LGE FGKV + + P + VA+K LK R ++ E + L Sbjct 473 VRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQ 532 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ------------ 999 H +++ G ++ L ++ Y G L ++L P +G Sbjct 533 HPNVVCLLGVVTK--DQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPP 590 Query 1000 -LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 + QI GM YL + H +H+DLA RNVL+ + VKI D GL + V +YY++ Sbjct 591 DFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREV-YAADYYKLL 649 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 + P+ W APE + KF SD+WS+GV L+E+ ++ G + Sbjct 650 GNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSY---------GLQPYCGYSNQD 700 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + E++ + LP PD CP VY LM CW S RP F+++ Sbjct 701 -----VVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDI 742 Score = 57.0 bits (136), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 77/342 (23%), Positives = 136/342 (40%), Gaps = 67/342 (20%) Query 548 RRCCLPQPGETSNL-IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606 RR + P + + +I + +A + ++LS + F + LG+ VY+G Sbjct 441 RRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRF----------MEELGEDRFGKVYKG 490 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQV 665 L G+ Q V +K L D + + F A L +++ Sbjct 491 HLFGPAPGE-------------------QTQAVAIKTLKDKAEGPLREEFRHEAMLRARL 531 Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV----------------PMA 709 H ++ + GV + M+ Y HG L +L H P Sbjct 532 QHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPD 591 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALS 768 + +VAQ +A+ + YL + ++VH ++ RN+L+ +L +K+SD G+ + Sbjct 592 FVHLVAQ-IAAGMEYLSSHHVVHKDLATRNVLVYDKLN--------VKISDLGLFREVYA 642 Query 769 RE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + + I W+APE + G S+ + D W +G L E+ G P S + Sbjct 643 ADYYKLLGNSLLPIRWMAPEAIMYGKFSIDS--DIWSYGVVLWEVFSYGLQPYCGYSNQD 700 Query 823 KEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 + + LP P CP + L +C P++RP F+ I Sbjct 701 VVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDI 742 >sp|Q54PX0|Y4251_DICDI Probable serine/threonine-protein kinase DDB_G0284251 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0284251 PE=3 SV=1 Length=496 Score = 117 bits (292), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 84/276 (30%), Positives = 137/276 (50%), Gaps = 28/276 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG+V + N TGE VA+K + ++ K E++IL L H +I+K Sbjct 42 IGRGAFGQV----FKGLNGKTGEFVAIKQIDSNKIDESSLQSVKGEVEILHKLRHNNIVK 97 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-LLFAQQICEGMAYLHAQHYI 1020 G E Q + L ++EYV GSLRD + + +L +++ Q+ +G+AYLH+ I Sbjct 98 VLGVVEVQAQ--LNFILEYVENGSLRDVIEKFGPLSEELCIIYLYQMLQGLAYLHSNKVI 155 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ A N+L+ + ++K+ DFG+A + + R G +P +W APE ++ Sbjct 156 HRDIKASNILITKEGVIKLADFGVASQI-DSESQLRFSVVG-TP-YWMAPESIEISGCSS 212 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ASD+WS G T+ ELLT +PP L Q + R+ + P P Sbjct 213 ASDIWSLGSTMIELLTG-----NPPYYTL------QPMAAMFRIVS----DQHPPFPTDI 257 Query 1141 PCEVYHLMKNCWETEASFRPTFENLI--PILKTVHE 1174 E + ++ + + RPT + L+ PI T+ + Sbjct 258 SKEFLDYFQQSFKKDPTQRPTAQELLQHPIFFTLQK 293 Score = 60.8 bits (146), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 53/210 (25%), Positives = 95/210 (45%), Gaps = 17/210 (8%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 ++ ++ H ++ V GV + + EYVE+G L + + G + ++ Q+ Sbjct 86 ILHKLRHNNIVKVLGVVEVQAQLNFILEYVENGSLRDVIEK-FGPLSEELCIIYLYQMLQ 144 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE---RVERIP 777 L+YL + ++H ++ NIL+ + G+ IKL+D GV S + V P Sbjct 145 GLAYLHSNKVIHRDIKASNILITKEGV-------IKLADFGVASQIDSESQLRFSVVGTP 197 Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP-SEKEHFYQRQH-RLP 834 W+APE + + S+A D W G+T++E+ G P + P + QH P Sbjct 198 YWMAPESIE--ISGCSSASDIWSLGSTMIEL-LTGNPPYYTLQPMAAMFRIVSDQHPPFP 254 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + Q +PTQRP+ + +L+ Sbjct 255 TDISKEFLDYFQQSFKKDPTQRPTAQELLQ 284 >sp|Q08156|KIT_CHICK Mast/stem cell growth factor receptor Kit OS=Gallus gallus OX=9031 GN=KIT PE=2 SV=1 Length=960 Score = 119 bits (298), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 65/192 (34%), Positives = 110/192 (57%), Gaps = 17/192 (9%) Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 ++ + LL F+ Q+ +GM++L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Sbjct 748 ALDVEDLLSFSYQVAKGMSFLASKNCIHRDLAARNILLTHGRITKICDFGLARDI-RNDS 806 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 Y V+ + PV W APE + + + SDVWS+G+ L+EL + SS P Sbjct 807 NYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGILLWELFS-LGSSPYP--------- 856 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 G + ++++ G R+ P+ P E+Y +MK+CW+ + RPTF+ I++ + Sbjct 857 ---GMPVDSKFYKMIKEGYRMFSPECSPPEMYDIMKSCWDADPLQRPTFKQ---IVQLIE 910 Query 1174 EKYQGQAPSVFS 1185 ++ AP V++ Sbjct 911 QQLSDNAPRVYA 922 Score = 57.8 bits (138), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 41/161 (25%), Positives = 72/161 (45%), Gaps = 22/161 (14%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + Q+A +S+L +KN +H ++ RNILL K+ D G+ + V Sbjct 758 SYQVAKGMSFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIRNDSNYVV 810 Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY- 827 + + W+APE + + + D W +G L E+ G +P K FY Sbjct 811 KGNARLPVKWMAPESIFNCVYTFES--DVWSYGILLWELFSLGSSPYPGMPVDSK--FYK 866 Query 828 --QRQHRLPEPSC--PQLATLTSQCLTYEPTQRPSFRTILR 864 + +R+ P C P++ + C +P QRP+F+ I++ Sbjct 867 MIKEGYRMFSPECSPPEMYDIMKSCWDADPLQRPTFKQIVQ 907 Score = 37.0 bits (84), Expect = 1.4, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689 + V +K+L PS H E +LMS++ +H ++ + G C G +++TEY Sbjct 604 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHINIVNLLGACTIGGPTLVITEY 658 Query 690 VEHGPLDVWLRRER 703 +G L +LRR+R Sbjct 659 CCYGDLLNFLRRKR 672 >sp|Q9Z138|ROR2_MOUSE Tyrosine-protein kinase transmembrane receptor ROR2 OS=Mus musculus OX=10090 GN=Ror2 PE=1 SV=2 Length=944 Score = 119 bits (298), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 81/287 (28%), Positives = 131/287 (46%), Gaps = 35/287 (12%) Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 ++ + +LGE FGKV + + P + VA+K LK R ++QE + L Sbjct 473 VRFMEELGEDRFGKVYKGHLFGPAPGEPTQAVAIKTLKDKAEGPLREEFRQEAMLRARLQ 532 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ------------ 999 H +I+ G ++ L ++ Y G L ++L P +G Sbjct 533 HPNIVCLLGVVTK--DQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPP 590 Query 1000 -LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 + QI GM +L + H +H+DLA RNVL+ + V+I D GL + V +YY++ Sbjct 591 DFVHVVAQIAAGMEFLSSHHVVHKDLATRNVLVYDKLNVRISDLGLFREV-YSADYYKLM 649 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 + P+ W +PE + KF SD+WS+GV L+E+ ++ G + Sbjct 650 GNSLLPIRWMSPEAVMYGKFSIDSDIWSYGVVLWEVFSY---------GLQPYCGYSNQD 700 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + E++ + LP PD CP VY LM CW S RP F+++ Sbjct 701 -----VVEMIRSRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDI 742 Score = 60.1 bits (144), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 80/356 (22%), Positives = 143/356 (40%), Gaps = 70/356 (20%) Query 548 RRCCLPQPGETSNL-IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606 RR + P + + +I + +A + ++LS + F + LG+ VY+G Sbjct 441 RRQLMASPSQDMEMPLISQHKQAKLKEISLSTVRF----------MEELGEDRFGKVYKG 490 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQV 665 L G+P + V +K L D + + F + A L +++ Sbjct 491 HLFGPAPGEPTQA-------------------VAIKTLKDKAEGPLREEFRQEAMLRARL 531 Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV----------------PMA 709 H ++ + GV + M+ Y HG L +L H P Sbjct 532 QHPNIVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPD 591 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALS 768 + VVAQ +A+ + +L + ++VH ++ RN+L+ +L +++SD G+ S Sbjct 592 FVHVVAQ-IAAGMEFLSSHHVVHKDLATRNVLVYDKLN--------VRISDLGLFREVYS 642 Query 769 RE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + + I W++PE + G S+ + D W +G L E+ G P S + Sbjct 643 ADYYKLMGNSLLPIRWMSPEAVMYGKFSIDS--DIWSYGVVLWEVFSYGLQPYCGYSNQD 700 Query 823 KEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI---LRDLTRLQPHN 873 + + LP P CP + L +C P++RP F+ I LR L +N Sbjct 701 VVEMIRSRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRSWGNLSNYN 756 >sp|Q9V6K3|ROR2_DROME Tyrosine-protein kinase transmembrane receptor Ror2 OS=Drosophila melanogaster OX=7227 GN=Nrk PE=1 SV=2 Length=724 Score = 117 bits (294), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 84/282 (30%), Positives = 130/282 (46%), Gaps = 34/282 (12%) Query 900 IRDLGEGHFGKVSLYCYDP--TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +R LG+G FG+V P D +VAVK LK D Q + +++E +L H Sbjct 444 VRSLGQGAFGRV-FQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHP 502 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--------------PRHSIGLAQLLLF 1003 +I++ G C + + L+ EY+ G L ++L R + LL Sbjct 503 NIVRLLGVCALG--RPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQM 560 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 A I GM YL + ++HRDLA RN L++ VKI DFGL+ + +YY+ E+ Sbjct 561 AANIAAGMLYLSERKFVHRDLATRNCLINEHMAVKIADFGLSHKI-YLQDYYKGDENDFI 619 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 P+ W E + KF SDVW++G+ L+E+ + G+ + Sbjct 620 PIRWMPLESILYNKFSLESDVWAYGICLWEVFSF---------ALQPYFGLTHEE----- 665 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + ++ G L PD P VY LM+ CW + S RP F + Sbjct 666 VIKYIKEGNVLGCPDNTPLSVYALMRRCWNRKPSERPGFAEI 707 Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 76/324 (23%), Positives = 132/324 (41%), Gaps = 51/324 (16%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 +N+ +G + + R L +L + R D I + LGQG V++ R Sbjct 416 VTNVSDAKGTKPNAR---LEKLEYPRGD---IVYVRSLGQGAFGRVFQAR---------- 459 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676 LVP + ++L V +K+L D + + + F A L+++ H ++ + GV Sbjct 460 ------APGLVPDQ---EDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVRLLGV 510 Query 677 CVRGPENIMVTEYVEHGPLDVWLR------------RERGHVPMAWKMVVAQQLASALSY 724 C G ++ EY+ G L +LR ++R + + +A +A+ + Y Sbjct 511 CALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQMAANIAAGMLY 570 Query 725 LENKNLVHGNVCGRNILLAR---LGLAE-GTSPFIKLSDPGVGLGALSREERVERIPWLA 780 L + VH ++ RN L+ + +A+ G S I L D G E I W+ Sbjct 571 LSERKFVHRDLATRNCLINEHMAVKIADFGLSHKIYLQDYYKG-----DENDFIPIRWMP 625 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840 E + N S D W +G L E+ P + E + + + L P Sbjct 626 LESIL--YNKFSLESDVWAYGICLWEVFSFALQPYFGLTHEEVIKYIKEGNVLGCPDNTP 683 Query 841 LAT--LTSQCLTYEPTQRPSFRTI 862 L+ L +C +P++RP F I Sbjct 684 LSVYALMRRCWNRKPSERPGFAEI 707 >sp|O76411|SCD2_CAEEL ALK tyrosine kinase receptor homolog scd-2 OS=Caenorhabditis elegans OX=6239 GN=scd-2 PE=1 SV=3 Length=1421 Score = 118 bits (296), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 83/298 (28%), Positives = 137/298 (46%), Gaps = 47/298 (16%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTL 954 +++ R LG G+FG+V Y +G +AVK + +S + E + T Sbjct 976 IERGRVLGRGNFGEVYYGEY------SGVKLAVKMISRTFSASQASQSDFCNEALCMGTF 1029 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----------HSIGLAQLLLFA 1004 E++++ G D + + +EY+ G L ++ + ++ L+ Sbjct 1030 VDENVVRLIGI--DFEKVPYMIALEYMEGGDLLSFVKECRPNQVSLNPFQLAMSDLIKIC 1087 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDN---DRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 + G L Y+HRD+AARN+LL R+ KI DFG+AK + G EYYR+ Sbjct 1088 CDVAAGCKCLETFGYVHRDIAARNILLTTRGPQRVAKIADFGMAKEITYGTEYYRINGRT 1147 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA-----Q 1116 P+ W PE + F SD+WSFGV +E+ + +G+ + Sbjct 1148 MMPIKWTPPEAFIDGVFTTKSDIWSFGVLCWEVFS---------------LGVVPYPNRR 1192 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + +L LTE G RL P P VY LM++CW+T A+ RP F +++ I + + + Sbjct 1193 NEEVMLMLTE----GARLEYPYGIPTRVYQLMRDCWKTAAADRPKFVDVVEIFQDIQD 1246 Score = 41.2 bits (95), Expect = 0.084, Method: Compositional matrix adjust. Identities = 54/229 (24%), Positives = 83/229 (36%), Gaps = 24/229 (10%) Query 684 IMVTEYVEHGPLDVWLRRERGH--------VPMAWKMVVAQQLASALSYLENKNLVHGNV 735 ++ EY+E G L +++ R + + M+ + + +A+ LE VH ++ Sbjct 1048 MIALEYMEGGDLLSFVKECRPNQVSLNPFQLAMSDLIKICCDVAAGCKCLETFGYVHRDI 1107 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE--RVER-----IPWLAPECLPGGA 788 RNILL G K++D G+ E R+ I W PE G Sbjct 1108 AARNILLT----TRGPQRVAKIADFGMAKEITYGTEYYRINGRTMMPIKWTPPEAFIDGV 1163 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC--PQLATLTS 846 +T D W FG E+ G P +R E RL P ++ L Sbjct 1164 --FTTKSDIWSFGVLCWEVFSLGVVPYPNRRNEEVMLMLTEGARLEYPYGIPTRVYQLMR 1221 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895 C RP F ++ +Q + A V P PA T H + Sbjct 1222 DCWKTAAADRPKFVDVVEIFQDIQ-DDPASVGMPFPIHPAVRATFAHSQ 1269 >sp|Q28889|KIT_FELCA Mast/stem cell growth factor receptor Kit OS=Felis catus OX=9685 GN=KIT PE=2 SV=1 Length=978 Score = 117 bits (294), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%) Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ + Sbjct 773 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 831 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 PV W APE + + + SDVWS+G+ L+EL + SS P G Sbjct 832 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 878 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++ Sbjct 879 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 926 Score = 48.9 bits (115), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 38/161 (24%), Positives = 71/161 (44%), Gaps = 22/161 (14%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + Q+A +++L +KN +H ++ RNILL K+ D G+ + V Sbjct 774 SYQVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIKNDSNYVV 826 Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY- 827 + + W+APE + + + D W +G L E+ G +P K FY Sbjct 827 KGNARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYK 882 Query 828 --QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + R+ PE + ++ + C +P +RP+F+ I++ Sbjct 883 MIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQ 923 Score = 37.0 bits (84), Expect = 1.6, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689 + V +K+L PS H E +LMS++ +H ++ + G C G +++TEY Sbjct 619 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEY 673 Query 690 VEHGPLDVWLRRER 703 +G L +LRR+R Sbjct 674 CCYGDLLNFLRRKR 687 >sp|P43481|KIT_BOVIN Mast/stem cell growth factor receptor Kit OS=Bos taurus OX=9913 GN=KIT PE=2 SV=1 Length=977 Score = 117 bits (294), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%) Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ + Sbjct 773 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 831 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 PV W APE + + + SDVWS+G+ L+EL + SS P G Sbjct 832 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 878 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++ Sbjct 879 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 926 Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 44/194 (23%), Positives = 86/194 (44%), Gaps = 28/194 (14%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + Q+A +++L +KN +H ++ RNILL K+ D G+ + V Sbjct 774 SYQVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIKNDSNYVV 826 Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY- 827 + + W+APE + + + D W +G L E+ G +P K FY Sbjct 827 KGNARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYK 882 Query 828 --QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL----RDLTRLQPHNLADVLT 879 + R+ PE + ++ + C +P +RP+F+ I+ + ++ H +++ Sbjct 883 MIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLAN 942 Query 880 VNP--DSPASDPTV 891 +P ++PA D +V Sbjct 943 CSPHRENPAVDHSV 956 Score = 36.6 bits (83), Expect = 1.9, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689 + V +K+L PS H E +LMS++ +H ++ + G C G +++TEY Sbjct 619 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEY 673 Query 690 VEHGPLDVWLRRER 703 +G L +LRR+R Sbjct 674 CCYGDLLNFLRRKR 687 >sp|Q28317|KIT_CAPHI Mast/stem cell growth factor receptor Kit OS=Capra hircus OX=9925 GN=KIT PE=2 SV=1 Length=978 Score = 117 bits (294), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%) Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ + Sbjct 774 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 832 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 PV W APE + + + SDVWS+G+ L+EL + SS P G Sbjct 833 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 879 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++ Sbjct 880 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 927 Score = 50.8 bits (120), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 44/194 (23%), Positives = 86/194 (44%), Gaps = 28/194 (14%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + Q+A +++L +KN +H ++ RNILL K+ D G+ + V Sbjct 775 SYQVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIKNDSNYVV 827 Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY- 827 + + W+APE + + + D W +G L E+ G +P K FY Sbjct 828 KGNARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYK 883 Query 828 --QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL----RDLTRLQPHNLADVLT 879 + R+ PE + ++ + C +P +RP+F+ I+ + ++ H +++ Sbjct 884 MIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLAN 943 Query 880 VNP--DSPASDPTV 891 +P ++PA D +V Sbjct 944 CSPHRENPAVDHSV 957 Score = 36.6 bits (83), Expect = 1.8, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689 + V +K+L PS H E +LMS++ +H ++ + G C G +++TEY Sbjct 619 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEY 673 Query 690 VEHGPLDVWLRRER 703 +G L +LRR+R Sbjct 674 CCYGDLLNFLRRKR 687 >sp|O97799|KIT_CANLF Mast/stem cell growth factor receptor Kit OS=Canis lupus familiaris OX=9615 GN=KIT PE=2 SV=2 Length=979 Score = 117 bits (293), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%) Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ + Sbjct 775 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 833 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 PV W APE + + + SDVWS+G+ L+EL + SS P G Sbjct 834 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 880 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++ Sbjct 881 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 928 Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 48/195 (25%), Positives = 85/195 (44%), Gaps = 30/195 (15%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + Q+A +++L +KN +H ++ RNILL K+ D G+ + V Sbjct 776 SYQVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIKNDSNYVV 828 Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY- 827 + + W+APE + + + D W +G L E+ G +P K FY Sbjct 829 KGNARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYK 884 Query 828 --QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILR-------DLTRLQPHNLAD 876 + R+ PE + ++ + C +P +RP+F+ I++ D T NLA+ Sbjct 885 MIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISDSTNHIYSNLAN 944 Query 877 VLTVNPDSPASDPTV 891 + NP+ P D +V Sbjct 945 C-SPNPERPVVDHSV 958 Score = 36.6 bits (83), Expect = 1.8, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689 + V +K+L PS H E +LMS++ +H ++ + G C G +++TEY Sbjct 621 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEY 675 Query 690 VEHGPLDVWLRRER 703 +G L +LRR+R Sbjct 676 CCYGDLLNFLRRKR 689 >sp|Q2HWD6|KIT_PIG Mast/stem cell growth factor receptor Kit OS=Sus scrofa OX=9823 GN=KIT PE=2 SV=1 Length=972 Score = 117 bits (293), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%) Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ + Sbjct 768 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 826 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 PV W APE + + + SDVWS+G+ L+EL + SS P G Sbjct 827 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 873 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++ Sbjct 874 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 921 Score = 51.2 bits (121), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 44/192 (23%), Positives = 85/192 (44%), Gaps = 28/192 (15%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A +++L +KN +H ++ RNILL K+ D G+ + V + Sbjct 771 QVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIKNDSNYVVKG 823 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--- 827 + W+APE + + + D W +G L E+ G +P K FY Sbjct 824 NARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYKMI 879 Query 828 QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL----RDLTRLQPHNLADVLTVN 881 + R+ PE + ++ + C +P +RP+F+ I+ + ++ H +++ + Sbjct 880 KEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCS 939 Query 882 P--DSPASDPTV 891 P ++PA D +V Sbjct 940 PHRENPAVDHSV 951 Score = 36.6 bits (83), Expect = 1.9, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689 + V +K+L PS H E +LMS++ +H ++ + G C G +++TEY Sbjct 614 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEY 668 Query 690 VEHGPLDVWLRRER 703 +G L +LRR+R Sbjct 669 CCYGDLLNFLRRKR 682 >sp|G4N7X0|MST11_PYRO7 Mitogen-activated protein kinase kinae kinase MST11 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507 GN=MST11 PE=1 SV=1 Length=915 Score = 117 bits (293), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 71/211 (34%), Positives = 113/211 (54%), Gaps = 24/211 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRS---------GWKQEIDILR 952 +G+G FG V L + T GE++AVK ++A G ++ K+EI +LR Sbjct 647 IGQGSFGCVYLALHAIT----GELLAVKQVEAPSPGANSQNDARKKSMIEALKREISLLR 702 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--FAQQICEG 1010 L H +I++Y GC + L + +EYVP GS++ L + L + L+ F +QI G Sbjct 703 DLRHPNIVQYLGCG--SSAEYLNIFLEYVPGGSVQTMLNSYG-ALPEPLVRSFVRQILNG 759 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-----EGHEYYRVREDGDSPV 1065 ++YLH + IHRD+ N+L+DN +KI DFG++K + G + R V Sbjct 760 LSYLHEREIIHRDIKGANILVDNKGTIKISDFGISKKIEATNLLNGANNNKHRPSLQGSV 819 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 FW APE +K+ + +D+WS G + E++T Sbjct 820 FWMAPEVVKQTSYTRKADIWSLGCLVVEMMT 850 Score = 43.1 bits (100), Expect = 0.019, Method: Compositional matrix adjust. Identities = 42/167 (25%), Positives = 70/167 (42%), Gaps = 24/167 (14%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMV-TEYVEHGPLDVWLRRERGHVPMAWKM 712 A SL+ + H ++ G C E + + EYV G + L G +P Sbjct 693 ALKREISLLRDLRHPNIVQYLG-CGSSAEYLNIFLEYVPGGSVQTMLN-SYGALPEPLVR 750 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-------- 764 +Q+ + LSYL + ++H ++ G NIL+ G IK+SD G+ Sbjct 751 SFVRQILNGLSYLHEREIIHRDIKGANILVDNKGT-------IKISDFGISKKIEATNLL 803 Query 765 -GALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 GA + + R + W+APE + S + D W G ++E+ Sbjct 804 NGANNNKHRPSLQGSVFWMAPEVV--KQTSYTRKADIWSLGCLVVEM 848 >sp|P10721|KIT_HUMAN Mast/stem cell growth factor receptor Kit OS=Homo sapiens OX=9606 GN=KIT PE=1 SV=1 Length=976 Score = 117 bits (293), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%) Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ + Sbjct 772 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 830 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 PV W APE + + + SDVWS+G+ L+EL + SS P G Sbjct 831 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 877 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++ Sbjct 878 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 925 Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 38/161 (24%), Positives = 71/161 (44%), Gaps = 22/161 (14%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + Q+A +++L +KN +H ++ RNILL K+ D G+ + V Sbjct 773 SYQVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIKNDSNYVV 825 Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY- 827 + + W+APE + + + D W +G L E+ G +P K FY Sbjct 826 KGNARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYK 881 Query 828 --QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + R+ PE + ++ + C +P +RP+F+ I++ Sbjct 882 MIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQ 922 Score = 36.6 bits (83), Expect = 1.9, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 39/74 (53%), Gaps = 12/74 (16%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689 + V +K+L PS H E +LMS++ +H ++ + G C G +++TEY Sbjct 618 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEY 672 Query 690 VEHGPLDVWLRRER 703 +G L +LRR+R Sbjct 673 CCYGDLLNFLRRKR 686 >sp|Q76II0|KIT_CALJA Mast/stem cell growth factor receptor Kit OS=Callithrix jacchus OX=9483 GN=KIT PE=2 SV=1 Length=972 Score = 117 bits (293), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%) Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ + Sbjct 768 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYV-VKGNAR 826 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 PV W APE + + + SDVWS+G+ L+EL + SS P G Sbjct 827 LPVKWMAPESIFNCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 873 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++ Sbjct 874 KFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIE 921 Score = 49.3 bits (116), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 38/161 (24%), Positives = 72/161 (45%), Gaps = 22/161 (14%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + Q+A +++L +KN +H ++ RNILL + K+ D G+ + V Sbjct 769 SYQVAKGMAFLASKNCIHRDLAARNILLTHGRIT-------KICDFGLARDIKNDSNYVV 821 Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY- 827 + + W+APE + + + D W +G L E+ G +P K FY Sbjct 822 KGNARLPVKWMAPESIFNCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYK 877 Query 828 --QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + R+ PE + ++ + C +P +RP+F+ I++ Sbjct 878 MIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQ 918 Score = 36.6 bits (83), Expect = 1.8, Method: Compositional matrix adjust. Identities = 30/104 (29%), Positives = 51/104 (49%), Gaps = 19/104 (18%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689 + V +K+L PS H E +LMS++ +H ++ + G C G +++TEY Sbjct 614 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEY 668 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHG 733 +G L +LRR+R + ++Q A + L KNL+H Sbjct 669 CCYGDLLNFLRRKRD------SFICSKQEDHAEAALY-KNLLHS 705 >sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens OX=9606 GN=MAP3K2 PE=1 SV=2 Length=619 Score = 115 bits (289), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 69/199 (35%), Positives = 106/199 (53%), Gaps = 9/199 (5%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS----GWKQEIDILRTLYHEH 958 LG+G FG+V L CYD TG +AVK ++ D S + EI +L+ L HE Sbjct 362 LGQGAFGRVYL-CYDV---DTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHER 417 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL-LFAQQICEGMAYLHAQ 1017 I++Y GC D EK+L + MEY+P GS++D L + + + +QI EG+ YLH+ Sbjct 418 IVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSN 477 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRD+ N+L D+ VK+GDFG +K + + +W +PE + Sbjct 478 MIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEG 537 Query 1078 FYYASDVWSFGVTLYELLT 1096 + +D+WS T+ E+LT Sbjct 538 YGRKADIWSVACTVVEMLT 556 Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust. Identities = 43/192 (22%), Positives = 76/192 (40%), Gaps = 30/192 (16%) Query 632 DRGQELRVVLKVLDPSHHDIAL---AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 D G+EL V DP + + A L+ + H + +G C+R P+ ++ Sbjct 377 DTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYG-CLRDPQEKTLSI 435 Query 689 YVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 ++E+ P + + + + + +Q+ + YL + +VH ++ G NIL G Sbjct 436 FMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTG 495 Query 747 LAEGTSPFIKLSDPGV----------GLGALSREERVERIP-WLAPECLPGGANSLSTAM 795 +KL D G G G S V P W++PE + G Sbjct 496 -------NVKLGDFGASKRLQTICLSGTGMKS----VTGTPYWMSPEVISG--EGYGRKA 542 Query 796 DKWGFGATLLEI 807 D W T++E+ Sbjct 543 DIWSVACTVVEM 554 >sp|P05532|KIT_MOUSE Mast/stem cell growth factor receptor Kit OS=Mus musculus OX=10090 GN=Kit PE=1 SV=3 Length=979 Score = 117 bits (292), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 60/168 (36%), Positives = 98/168 (58%), Gaps = 14/168 (8%) Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 F+ Q+ +GMA+L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ + Sbjct 774 FSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIRNDSNYV-VKGNAR 832 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 PV W APE + + + SDVWS+G+ L+EL + SS P G Sbjct 833 LPVKWMAPESIFSCVYTFESDVWSYGIFLWELFS-LGSSPYP------------GMPVDS 879 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + ++++ G R+ P+ P E+Y +MK CW+ + RPTF+ ++ +++ Sbjct 880 KFYKMIKEGFRMVSPEHAPAEMYDVMKTCWDADPLKRPTFKQVVQLIE 927 Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 45/188 (24%), Positives = 82/188 (44%), Gaps = 30/188 (16%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A +++L +KN +H ++ RNILL K+ D G+ + V + Sbjct 777 QVAKGMAFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIRNDSNYVVKG 829 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--- 827 + W+APE + + + D W +G L E+ G +P K FY Sbjct 830 NARLPVKWMAPESIFSCVYTFES--DVWSYGIFLWELFSLGSSPYPGMPVDSK--FYKMI 885 Query 828 QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILR-------DLTRLQPHNLADVL 878 + R+ PE + ++ + C +P +RP+F+ +++ D T+ NLA+ Sbjct 886 KEGFRMVSPEHAPAEMYDVMKTCWDADPLKRPTFKQVVQLIEKQISDSTKHIYSNLANC- 944 Query 879 TVNPDSPA 886 NP++P Sbjct 945 NPNPENPV 952 Score = 37.4 bits (85), Expect = 1.0, Method: Compositional matrix adjust. Identities = 30/104 (29%), Positives = 51/104 (49%), Gaps = 19/104 (18%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689 + V +K+L PS H E +LMS++ +H ++ + G C G +++TEY Sbjct 621 MTVAVKMLKPSAH-----LTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEY 675 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHG 733 +G L +LRR+R + ++Q A + L KNL+H Sbjct 676 CCYGDLLNFLRRKRD------SFIFSKQEEQAEAALY-KNLLHS 712 >sp|O61460|VAB1_CAEEL Ephrin receptor 1 OS=Caenorhabditis elegans OX=6239 GN=vab-1 PE=1 SV=1 Length=1122 Score = 117 bits (292), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 86/263 (33%), Positives = 123/263 (47%), Gaps = 32/263 (12%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 E VA+K LK+ + ++ + E I+ H ++I+ G + + +V EY+ G Sbjct 743 ETVAIKTLKSGSSAKAKAEFLTEATIMGQFSHPNVIRLIGVV--TSAEPVMIVAEYMANG 800 Query 985 SLRDYLPR-----HSIGLAQLLLFAQQICEGMAYLHAQHYIHR-----DLAARNVLLDND 1034 SL +L + ++ I GM YL Y+HR DLAARNVLLD + Sbjct 801 SLDQFLRNTDQRGEKVHWEKITEMLYGIASGMKYLTDMGYVHRVSFLRDLAARNVLLDME 860 Query 1035 RLVKIGDFGLAKAV-PEGH--EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091 KI DFGL++ V EG E G PV W APE + KF +SDVWSFGV + Sbjct 861 LRCKIADFGLSRGVRSEGSSVEPEYTTNGGKIPVRWTAPEAITHRKFTPSSDVWSFGVVI 920 Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 +E+ C + P + I++ + G RLP P CP +Y + + C Sbjct 921 WEV---CSFGERPYWDWTNQKVISEVMI-----------GYRLPPPMDCPMGLYRIAQWC 966 Query 1152 WETEASFRPTFENLIPILKTVHE 1174 W+ E RPTF L L T H+ Sbjct 967 WKMERHERPTFTQL---LATFHK 986 Score = 72.0 bits (175), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 72/257 (28%), Positives = 110/257 (43%), Gaps = 34/257 (13%) Query 639 VVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V +K L A A F A++M Q SH ++ + GV ++V EY+ +G LD Sbjct 745 VAIKTLKSGSSAKAKAEFLTEATIMGQFSHPNVIRLIGVVTSAEPVMIVAEYMANGSLDQ 804 Query 698 WLRR--ERGHVPMAWKMVVAQ--QLASALSYLENKNLVH-----GNVCGRNILLARLGLA 748 +LR +RG + W+ + +AS + YL + VH ++ RN+LL Sbjct 805 FLRNTDQRGE-KVHWEKITEMLYGIASGMKYLTDMGYVHRVSFLRDLAARNVLL------ 857 Query 749 EGTSPFIKLSDPGVGLGALSREERVE--------RIP--WLAPECLPGGANSLSTAMDKW 798 K++D G+ G S VE +IP W APE + + + D W Sbjct 858 -DMELRCKIADFGLSRGVRSEGSSVEPEYTTNGGKIPVRWTAPEAIT--HRKFTPSSDVW 914 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQR 856 FG + E+C GE P + + +RLP P CP L + C E +R Sbjct 915 SFGVVIWEVCSFGERPYWDWTNQKVISEVMIGYRLPPPMDCPMGLYRIAQWCWKMERHER 974 Query 857 PSFRTILRDLTR--LQP 871 P+F +L + LQP Sbjct 975 PTFTQLLATFHKYILQP 991 >sp|Q8RWL6|STY17_ARATH Serine/threonine-protein kinase STY17 OS=Arabidopsis thaliana OX=3702 GN=STY17 PE=1 SV=1 Length=570 Score = 115 bits (287), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 77/283 (27%), Positives = 140/283 (49%), Gaps = 33/283 (12%) Query 895 RYLKKIRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDIL 951 + LK + + G +G++ YC + VA+K LK + + + QE+ I+ Sbjct 290 KQLKIEKKVACGSYGELFRGTYC--------SQEVAIKILKPERVNAEMLREFSQEVYIM 341 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICE 1009 R + H++++++ G C +L +V E++ GS+ D+L +H + LL A + + Sbjct 342 RKVRHKNVVQFIGAC--TRSPNLCIVTEFMTRGSIYDFLHKHKGVFKIQSLLKVALDVSK 399 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 GM YLH + IHRDL N+L+D +VK+ DFG+A+ E V W A Sbjct 400 GMNYLHQNNIIHRDLKTANLLMDEHEVVKVADFGVARVQTESG----VMTAETGTYRWMA 455 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE ++ + + +DV+S+ + L+ELLT P +L + A G +++ Sbjct 456 PEVIEHKPYDHRADVFSYAIVLWELLT-----GELPYSYLTPLQAAVG---------VVQ 501 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +G R P + ++ L++ CW+ + + RP F +I +L + Sbjct 502 KGLRPKIPKETHPKLTELLEKCWQQDPALRPNFAEIIEMLNQL 544 Score = 73.2 bits (178), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 58/241 (24%), Positives = 108/241 (45%), Gaps = 22/241 (9%) Query 639 VVLKVLDPSHHDIAL--AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K+L P + + F + +M +V H ++ G C R P +VTE++ G + Sbjct 316 VAIKILKPERVNAEMLREFSQEVYIMRKVRHKNVVQFIGACTRSPNLCIVTEFMTRGSIY 375 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L + +G + + VA ++ ++YL N++H ++ N+L+ +K Sbjct 376 DFLHKHKGVFKIQSLLKVALDVSKGMNYLHQNNIIHRDLKTANLLM-------DEHEVVK 428 Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D GV G ++ E R W+APE + D + + L E+ G Sbjct 429 VADFGVARVQTESGVMTAETGTYR--WMAPEVIE--HKPYDHRADVFSYAIVLWEL-LTG 483 Query 812 EAPLQSRSPSEKE-HFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 E P +P + Q+ R +P+ + P+L L +C +P RP+F I+ L + Sbjct 484 ELPYSYLTPLQAAVGVVQKGLRPKIPKETHPKLTELLEKCWQQDPALRPNFAEIIEMLNQ 543 Query 869 L 869 L Sbjct 544 L 544 >sp|F8W3R9|ALK_DANRE ALK tyrosine kinase receptor OS=Danio rerio OX=7955 GN=alk PE=2 SV=2 Length=1705 Score = 117 bits (292), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 91/294 (31%), Positives = 130/294 (44%), Gaps = 47/294 (16%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGT-GE----MVAVKALKADCGPQHRSGWKQEI 948 +R + R LG G FG+V Y+ G GE VAVK L C Q + E Sbjct 1110 RRNISLTRGLGHGAFGEV----YEGLAVGIPGEPSPMQVAVKTLPEVCSEQDELDFLMEA 1165 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQ-----LVMEYVPLGSLRDYL----PR----HSI 995 I+ H++I++ G SLQ +++E + G L+ +L PR S+ Sbjct 1166 LIISKFSHQNIVRCIGV-------SLQALPHFILLELMAGGDLKSFLRETRPRLEHPSSL 1218 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGH 1052 + LL A+ I G YL +IHRD+AARN LL R+ KIGDFG+A+ + Sbjct 1219 TMVDLLNIARDIARGCQYLEENQFIHRDIAARNCLLTCKGPGRVAKIGDFGMARDIYRA- 1277 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 YYR PV W PE E F +D WSFGV L+E+ + L Sbjct 1278 SYYRKGGRAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFS--------------LG 1323 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + + + E + G R+ P CP VY +M W+ + RP F ++ Sbjct 1324 YMPYPSRSNQEVLEFVTNGGRMDPPKNCPGPVYRIMTQSWQHQPEDRPNFSTIL 1377 Score = 77.4 bits (189), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 79/301 (26%), Positives = 125/301 (42%), Gaps = 40/301 (13%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 V ++ I+ LG G VYEG L V G+P ++V Sbjct 1105 LKEVPRRNISLTRGLGHGAFGEVYEG-LAVGIPGEPSP------------------MQVA 1145 Query 641 LKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +K L + L F A ++S+ SH ++ GV ++ + ++ E + G L +L Sbjct 1146 VKTLPEVCSEQDELDFLMEALIISKFSHQNIVRCIGVSLQALPHFILLELMAGGDLKSFL 1205 Query 700 RRERGHV--PMAWKMV----VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 R R + P + MV +A+ +A YLE +H ++ RN LL +G Sbjct 1206 RETRPRLEHPSSLTMVDLLNIARDIARGCQYLEENQFIHRDIAARNCLLT----CKGPGR 1261 Query 754 FIKLSDPGVGL----GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 K+ D G+ + R+ +P W+ PE G ++ D W FG L EI Sbjct 1262 VAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPPEAFMEGI--FTSKTDTWSFGVLLWEI 1319 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILRD 865 G P SRS E F R+ P +CP + + +Q ++P RP+F TIL Sbjct 1320 FSLGYMPYPSRSNQEVLEFVTNGGRMDPPKNCPGPVYRIMTQSWQHQPEDRPNFSTILER 1379 Query 866 L 866 + Sbjct 1380 I 1380 >sp|P00545|KFMS_FSVMD Tyrosine-protein kinase transforming protein fms OS=Feline sarcoma virus (strain McDonough) OX=11778 GN=V-FMS PE=1 SV=2 Length=978 Score = 116 bits (291), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 61/176 (35%), Positives = 101/176 (57%), Gaps = 18/176 (10%) Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 L LL F+ Q+ +GMA+L +++ IHRD+AARNVLL + R+ KIGDFGLA+ + Y Sbjct 784 LRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGRVAKIGDFGLARDIMNDSNYI- 842 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA- 1115 V+ + PV W APE + + + SDVWS+G+ L+E+ + +G+ Sbjct 843 VKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFS---------------LGLNP 887 Query 1116 -QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 G + + +L++ G ++ +P P +Y +M+ CW E + RPTF+ + +L+ Sbjct 888 YPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTRRPTFQQICSLLQ 943 Score = 52.4 bits (124), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 43/165 (26%), Positives = 75/165 (45%), Gaps = 22/165 (13%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV- 773 + Q+A +++L +KN +H +V RN+LL +A K+ D G+ ++ + Sbjct 791 SSQVAQGMAFLASKNCIHRDVAARNVLLTSGRVA-------KIGDFGLARDIMNDSNYIV 843 Query 774 ---ERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 R+P W+APE + ++ + D W +G L EI G P + K FY+ Sbjct 844 KGNARLPVKWMAPESIFDCVYTVQS--DVWSYGILLWEIFSLGLNPYPGILVNSK--FYK 899 Query 829 -----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 Q P + + ++ C EPT+RP+F+ I L + Sbjct 900 LVKDGYQMAQPAFAPKNIYSIMQACWALEPTRRPTFQQICSLLQK 944 >sp|Q5MD89|VGFR3_DANRE Vascular endothelial growth factor receptor 3 OS=Danio rerio OX=7955 GN=flt4 PE=2 SV=1 Length=1357 Score = 117 bits (292), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 91/323 (28%), Positives = 142/323 (44%), Gaps = 73/323 (23%) Query 903 LGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEH 958 LG G FGKV S++ +D + VAVK LK E+ IL + H + Sbjct 872 LGHGAFGKVIEASIFGHD--KKSSANTVAVKMLKEGATASEHKALMSELKILIHIGNHLN 929 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---------------------------- 990 ++ G C + L +++EY G+L ++L Sbjct 930 VVNLLGACT-KPNGPLMVIVEYCKYGNLSNFLRAKREFFLPYRDRSPKTQSQVRRMIEAG 988 Query 991 ----------------PRHSIG--------LAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 PR ++ + L+ ++ Q+ GM +L ++ IHRDLAA Sbjct 989 QASQSEHQPSTSSTNPPRVTVDDLWKTPLTIEDLICYSFQVARGMEFLASRKCIHRDLAA 1048 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RN+LL + +VKI DFGLA+ + + +Y R + + P+ W APE + + + SDVWS Sbjct 1049 RNILLSENNVVKICDFGLARDIYKDPDYVR-KGNARLPLKWMAPESIFDKVYTSQSDVWS 1107 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 FGV L+E+ + +S P + E + L+ G R+ PD E+Y Sbjct 1108 FGVLLWEIFS-LGASPYPGIQIDE------------DFCKRLKDGTRMRAPDNASPEIYG 1154 Query 1147 LMKNCWETEASFRPTFENLIPIL 1169 +M CW+ E RPTF L+ IL Sbjct 1155 IMLACWQGEPRERPTFPALVEIL 1177 Score = 52.0 bits (123), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 41/168 (24%), Positives = 73/168 (43%), Gaps = 22/168 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V + Sbjct 1028 QVARGMEFLASRKCIHRDLAARNILLSENNV-------VKICDFGLARDIYKDPDYVRKG 1080 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + ++ D W FG L EI G +P E F +R Sbjct 1081 NARLPLKWMAPESIFDKV--YTSQSDVWSFGVLLWEIFSLGASPYPGIQIDED--FCKRL 1136 Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 + R P+ + P++ + C EP +RP+F ++ L L N Sbjct 1137 KDGTRMRAPDNASPEIYGIMLACWQGEPRERPTFPALVEILGDLLQEN 1184 >sp|A9SY39|M3K1A_PHYPA Mitogen-activated protein kinase kinase kinase 1a OS=Physcomitrium patens OX=3218 GN=MEKK1a PE=2 SV=2 Length=759 Score = 115 bits (289), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 84/269 (31%), Positives = 132/269 (49%), Gaps = 31/269 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQ---EIDILRTLYHEH 958 LG G FG S+Y N G AVK + AD G R KQ EI +L + H + Sbjct 432 LGSGTFG--SVYEGVARN---GTFFAVKEVNLADEGKLGRQAVKQLEREIALLSDIQHPN 486 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I++Y G ++ E L + +E + GSL + ++ + Q+ + +QI G+ YLH + Sbjct 487 IVQYLGT--ERTEDKLYIFLELLNKGSLANLYRKYGLFYEQIKAYTEQILTGLKYLHDRK 544 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK-EYK 1077 IHRD+ N+L+D + +VK+ DFG+AK V E + + W APE + + + Sbjct 545 IIHRDIKCANILVDTNGVVKLADFGMAKQV----EKFGFAKSFVGSAHWMAPEVVDPKQQ 600 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + +A+D+WS G T+ E+ T + PP LE I + + RGE P Sbjct 601 YNFAADIWSLGCTVLEMAT-----EGPPFGELEFIAVFWK----------IGRGEAPLIP 645 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 D E+ + C + +AS RPT + L+ Sbjct 646 DDLEDELKDFIAQCLQVDASKRPTCDMLL 674 Score = 41.6 bits (96), Expect = 0.058, Method: Compositional matrix adjust. Identities = 68/299 (23%), Positives = 118/299 (39%), Gaps = 86/299 (29%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LG GT +VYEG R +E + DE L GR ++L +IAL Sbjct 432 LGSGTFGSVYEGVARNGTFFAVKEVNLADEGKL--GRQAVKQL----------EREIAL- 478 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 +S + H ++ G + + E + G L L R+ G + ++ + Sbjct 479 -------LSDIQHPNIVQYLGTERTEDKLYIFLELLNKGSL-ANLYRKYG---LFYEQIK 527 Query 715 A--QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 A +Q+ + L YL ++ ++H ++ NIL+ G+ +KL+D G+ ++ Sbjct 528 AYTEQILTGLKYLHDRKIIHRDIKCANILVDTNGV-------VKLADFGMA-------KQ 573 Query 773 VERIP----------WLAPECLPGGANSLSTAMDKWGFGATLLEICFD------------ 810 VE+ W+APE + + A D W G T+LE+ + Sbjct 574 VEKFGFAKSFVGSAHWMAPEVV-DPKQQYNFAADIWSLGCTVLEMATEGPPFGELEFIAV 632 Query 811 ------GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 GEAPL +P+ +L +QCL + ++RP+ +L Sbjct 633 FWKIGRGEAPL-----------------IPDDLEDELKDFIAQCLQVDASKRPTCDMLL 674 >sp|P13369|CSF1R_FELCA Macrophage colony-stimulating factor 1 receptor OS=Felis catus OX=9685 GN=CSF1R PE=2 SV=1 Length=980 Score = 115 bits (289), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 61/176 (35%), Positives = 101/176 (57%), Gaps = 18/176 (10%) Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 L LL F+ Q+ +GMA+L +++ IHRD+AARNVLL + R+ KIGDFGLA+ + Y Sbjct 750 LRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGRVAKIGDFGLARDIMNDSNYI- 808 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA- 1115 V+ + PV W APE + + + SDVWS+G+ L+E+ + +G+ Sbjct 809 VKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFS---------------LGLNP 853 Query 1116 -QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 G + + +L++ G ++ +P P +Y +M+ CW E + RPTF+ + +L+ Sbjct 854 YPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTRRPTFQQICSLLQ 909 Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 40/159 (25%), Positives = 72/159 (45%), Gaps = 22/159 (14%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + Q+A +++L +KN +H +V RN+LL +A K+ D G+ ++ + Sbjct 757 SSQVAQGMAFLASKNCIHRDVAARNVLLTSGRVA-------KIGDFGLARDIMNDSNYIV 809 Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 + + W+APE + ++ + D W +G L EI G P + K FY+ Sbjct 810 KGNARLPVKWMAPESIFDCVYTVQS--DVWSYGILLWEIFSLGLNPYPGILVNSK--FYK 865 Query 829 -----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 Q P + + ++ C EPT+RP+F+ I Sbjct 866 LVKDGYQMAQPAFAPKNIYSIMQACWALEPTRRPTFQQI 904 >sp|P07333|CSF1R_HUMAN Macrophage colony-stimulating factor 1 receptor OS=Homo sapiens OX=9606 GN=CSF1R PE=1 SV=2 Length=972 Score = 115 bits (289), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 61/176 (35%), Positives = 99/176 (56%), Gaps = 18/176 (10%) Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 L LL F+ Q+ +GMA+L +++ IHRD+AARNVLL N + KIGDFGLA+ + Y Sbjct 752 LRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYI- 810 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA- 1115 V+ + PV W APE + + + SDVWS+G+ L+E+ + +G+ Sbjct 811 VKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFS---------------LGLNP 855 Query 1116 -QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 G + + +L++ G ++ +P P +Y +M+ CW E + RPTF+ + L+ Sbjct 856 YPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQICSFLQ 911 Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 42/159 (26%), Positives = 72/159 (45%), Gaps = 22/159 (14%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV- 773 + Q+A +++L +KN +H +V RN+LL +A K+ D G+ ++ + Sbjct 759 SSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVA-------KIGDFGLARDIMNDSNYIV 811 Query 774 ---ERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 R+P W+APE + ++ + D W +G L EI G P + K FY+ Sbjct 812 KGNARLPVKWMAPESIFDCVYTVQS--DVWSYGILLWEIFSLGLNPYPGILVNSK--FYK 867 Query 829 -----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 Q P + + ++ C EPT RP+F+ I Sbjct 868 LVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQI 906 >sp|P42159|RTK2_GEOCY Class II receptor tyrosine kinase OS=Geodia cydonium OX=6047 GN=TK PE=2 SV=2 Length=605 Score = 114 bits (285), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 74/226 (33%), Positives = 113/226 (50%), Gaps = 30/226 (13%) Query 897 LKKIRDLGEGHFGKVSLY----------CY----DPTNDGTGEMVAVKALKADCGPQHRS 942 +++++ +G G FG V L C DP+ +VAVK LK D + R Sbjct 346 IREVKQIGVGQFGAVVLAEMTGLSGSERCVPTKRDPSMLNGVALVAVKKLKPDVSEEVRQ 405 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-------- 994 + +EI + L H+ I++ C K +VMEY+ G L +L ++ Sbjct 406 SFDKEIKFVSQLQHDSIVQLLAVCTH--SKHPFIVMEYMENGDLNQFLQKYQMVDDDSAL 463 Query 995 ----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 I + LL A QI GM YL + +Y+HRDLA RN L+ ++ +KI DFG+++ + E Sbjct 464 YSNQIPPSTLLYMAVQIASGMVYLSSLNYVHRDLATRNCLVGSNFRIKISDFGMSRNLYE 523 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 YYRVR P+ W A E +F SD W++GVT++E+ T Sbjct 524 -RVYYRVRGRAMLPIRWMATESFYG-RFSEKSDAWAYGVTVWEIYT 567 Score = 64.7 bits (156), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 50/186 (27%), Positives = 84/186 (45%), Gaps = 27/186 (15%) Query 639 VVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V +K L P ++ +F + +SQ+ H + + VC +V EY+E+G L+ Sbjct 390 VAVKKLKPDVSEEVRQSFDKEIKFVSQLQHDSIVQLLAVCTHSKHPFIVMEYMENGDLNQ 449 Query 698 WLRRER----------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 +L++ + +P + + +A Q+AS + YL + N VH ++ RN L+ Sbjct 450 FLQKYQMVDDDSALYSNQIPPSTLLYMAVQIASGMVYLSSLNYVHRDLATRNCLV----- 504 Query 748 AEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFG 801 G++ IK+SD G+ R R I W+A E G S D W +G Sbjct 505 --GSNFRIKISDFGMSRNLYERVYYRVRGRAMLPIRWMATESFYG---RFSEKSDAWAYG 559 Query 802 ATLLEI 807 T+ EI Sbjct 560 VTVWEI 565 >sp|Q9FGB1|CBC2_ARATH Serine/threonine-protein kinase 52 OS=Arabidopsis thaliana OX=3702 GN=CBC2 PE=1 SV=1 Length=385 Score = 111 bits (278), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 89/305 (29%), Positives = 137/305 (45%), Gaps = 56/305 (18%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ-HRS---------GWKQEIDILR 952 L G FG V YD G+ VAVK L D G + HRS + QE+ + Sbjct 88 LARGTFGTVHRGIYD------GQDVAVKLL--DWGEEGHRSEAEIVSLRADFAQEVAVWH 139 Query 953 TLYHEHIIKYKGCCEDQGEKSLQL----------------VMEYVPLGSLRDYL---PRH 993 L H ++ K+ G G LQL V+EY+P G+L+ YL R Sbjct 140 KLDHPNVTKFIGAT--MGASGLQLQTESGPLAMPNNICCVVVEYLPGGALKSYLIKNRRR 197 Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + ++ A + G++YLH+Q +HRD+ N+LLD R VKI DFG+A+ V + Sbjct 198 KLTFKIVVQLALDLARGLSYLHSQKIVHRDVKTENMLLDKTRTVKIADFGVAR-VEASNP 256 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 E G + + APE L + DV+SFG+ L+E+ +C P F E+ Sbjct 257 NDMTGETG--TLGYMAPEVLNGNPYNRKCDVYSFGICLWEI--YCCDMPYPDLTFSEVT- 311 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + ++ + R P CP + +MK CW+ RP + ++P+L+++ Sbjct 312 -----------SAVVRQNLRPDIPRCCPSALAAVMKRCWDANPDKRPEMDEVVPMLESID 360 Query 1174 EKYQG 1178 G Sbjct 361 TTKGG 365 Score = 66.2 bits (160), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 87/329 (26%), Positives = 139/329 (42%), Gaps = 40/329 (12%) Query 557 ETSNLIIMRGARASPRTLNLSQLSFHR-------VDQKEITQLSHLGQGTRTNVYEG--- 606 +T+ + I A +SP TLN R +D ++ + L +GT V+ G Sbjct 43 DTTAVAIGGSASSSPVTLNGGGFVGKRKQRLEWEIDPSKLIIKTVLARGTFGTVHRGIYD 102 Query 607 --RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664 + V+ EEG + + + D QE+ V K+ P+ A + L Q Sbjct 103 GQDVAVKLLDWGEEGHRSEAEIVSLRADFAQEVAVWHKLDHPNVTKFIGATMGASGLQLQ 162 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV--AQQLASAL 722 LA + +C +V EY+ G L +L + R + +K+VV A LA L Sbjct 163 TESGPLAMPNNICC------VVVEYLPGGALKSYLIKNRRR-KLTFKIVVQLALDLARGL 215 Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE----RIPW 778 SYL ++ +VH +V N+LL + + +K++D GV S + + + Sbjct 216 SYLHSQKIVHRDVKTENMLLDK-------TRTVKIADFGVARVEASNPNDMTGETGTLGY 268 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEI-CFDGEAPLQSRSPSEKEHFYQRQHRLPE-P 836 +APE L G N + D + FG L EI C D P + SE RQ+ P+ P Sbjct 269 MAPEVLNG--NPYNRKCDVYSFGICLWEIYCCD--MPYPDLTFSEVTSAVVRQNLRPDIP 324 Query 837 SC--PQLATLTSQCLTYEPTQRPSFRTIL 863 C LA + +C P +RP ++ Sbjct 325 RCCPSALAAVMKRCWDANPDKRPEMDEVV 353 >sp|Q55GU0|Y9955_DICDI Probable serine/threonine-protein kinase DDB_G0267514 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0267514 PE=3 SV=1 Length=916 Score = 115 bits (288), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 90/280 (32%), Positives = 133/280 (48%), Gaps = 30/280 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--DCGPQHRSGWKQEIDILRTL 954 LK LGEG FG V + G VA+K +K D Q +++E+ IL L Sbjct 662 LKISSKLGEGTFGVVYKGLW------RGSSVAIKQIKINEDVNNQVLEEFRKELTILSRL 715 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--FAQQICEGMA 1012 H +I+ C +L + EY+P GSL D L I + L A QI +GM Sbjct 716 RHPNIVLLMAACT--APPNLCFITEYLPGGSLYDALHSKKIKMNMQLYKKLAIQIAQGMN 773 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 YLH IHRD+ + N+LLD VKI DFGL+K + E + + SP+ W +PE Sbjct 774 YLHLSGVIHRDIKSLNLLLDEHMNVKICDFGLSKLKSKSTE---MTKSIGSPI-WMSPEL 829 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 L + DV++FG+ L+EL T L G+ Q+ + T+ L Sbjct 830 LMGEDYTEKVDVYAFGIILWEL----------GTGELPYSGLDSVQLALAVTTKSL---- 875 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 R P P+ P ++ HL++ CW + RP+F ++ +L + Sbjct 876 RPPIPNAWPYQLSHLIQACWHQDPLKRPSFTEILNLLNEI 915 Score = 62.8 bits (151), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 71/323 (22%), Positives = 127/323 (39%), Gaps = 41/323 (13%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 Q N++ G+ P + S + E+ S LG+GT VY+G R Sbjct 627 QYNNQGNILKNSGSVVEPPSQQQQYFSDIEISFSELKISSKLGEGTFGVVYKGLWR---- 682 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVV-LKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672 G + + +K+ + ++ + F + +++S++ H ++ Sbjct 683 --------------------GSSVAIKQIKINEDVNNQVLEEFRKELTILSRLRHPNIVL 722 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVH 732 + C P +TEY+ G L L ++ + M +A Q+A ++YL ++H Sbjct 723 LMAACTAPPNLCFITEYLPGGSLYDALHSKKIKMNMQLYKKLAIQIAQGMNYLHLSGVIH 782 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---WLAPECLPGGAN 789 ++ N+LL +K+ D G+ E + I W++PE L G Sbjct 783 RDIKSLNLLLDE-------HMNVKICDFGLSKLKSKSTEMTKSIGSPIWMSPELLMG--E 833 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPSC--PQLATLTS 846 + +D + FG L E+ GE P + + R P P+ QL+ L Sbjct 834 DYTEKVDVYAFGIILWELG-TGELPYSGLDSVQLALAVTTKSLRPPIPNAWPYQLSHLIQ 892 Query 847 QCLTYEPTQRPSFRTILRDLTRL 869 C +P +RPSF IL L + Sbjct 893 ACWHQDPLKRPSFTEILNLLNEI 915 >sp|Q5PP29|PBL4_ARATH Probable serine/threonine-protein kinase PBL4 OS=Arabidopsis thaliana OX=3702 GN=PBL4 PE=2 SV=1 Length=412 Score = 112 bits (279), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 90/281 (32%), Positives = 131/281 (47%), Gaps = 19/281 (7%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +GEG FG V D P+ G+G +VAVK LK + HR W E+D L L+H Sbjct 89 IGEGGFGYVYKGWIDERTLSPSKPGSGMVVAVKKLKEEGFQGHRQ-WLAEVDCLGRLHHM 147 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYL 1014 +++K G C +G+ LV EY+P GSL ++L R I + A G+A+L Sbjct 148 NLVKLIGYCS-KGDHIRLLVYEYMPKGSLENHLFRRGAEPIPWRTRIKVAIGAARGLAFL 206 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H I+RD A N+LLD++ K+ DFGLAK P G + V + APE + Sbjct 207 HEAQVIYRDFKASNILLDSEFNAKLSDFGLAKVGPTGDRTH-VSTQVMGTQGYAAPEYVA 265 Query 1075 EYKFYYASDVWSFGVTLYELLT---HCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLE 1129 + SDV+SFGV L ELL+ D ++ + L I + V R+ + Sbjct 266 TGRITAKSDVYSFGVVLLELLSGRLTVDKTKVGVERNLVDWAIPYLGDKRKVFRIMDTKL 325 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 G+ P K C + C E RP +++ L+ Sbjct 326 GGQ---YPHKGACLTANTALQCLNQEPKLRPKMSDVLSTLE 363 >sp|Q9ZQ31|STY13_ARATH Serine/threonine-protein kinase STY13 OS=Arabidopsis thaliana OX=3702 GN=STY13 PE=1 SV=2 Length=411 Score = 111 bits (277), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 82/291 (28%), Positives = 138/291 (47%), Gaps = 44/291 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQH----RSGWKQEIDILRTLYHE 957 +G FGK+ Y+ GE VA+K L + + P+ ++QE+ +L L H Sbjct 136 FAQGAFGKLYKGTYN------GEDVAIKILERPENSPEKAQFMEQQFQQEVSMLANLKHP 189 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ---ICEGMAYL 1014 +I+++ G C + +V EY GS+R +L R L L +Q + GMAY+ Sbjct 190 NIVRFIGAC--RKPMVWCIVTEYAKGGSVRQFLTRRQNRAVPLKLAVKQALDVARGMAYV 247 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP----VFWYAP 1070 H +++IHRDL + N+L+ D+ +KI DFG+A+ V+ +G +P W AP Sbjct 248 HGRNFIHRDLKSDNLLISADKSIKIADFGVAR--------IEVQTEGMTPETGTYRWMAP 299 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT-ELLE 1129 E ++ + DV+SFG+ L+EL+T Q+ MT ++ ++ Sbjct 300 EMIQHRAYNQKVDVYSFGIVLWELITGLLPFQN---------------MTAVQAAFAVVN 344 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180 RG R P+ C + +M CW+ RP F ++ +L+ + A Sbjct 345 RGVRPTVPNDCLPVLSDIMTRCWDANPEVRPCFVEVVKLLEAAETEIMTTA 395 Score = 59.3 bits (142), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 51/214 (24%), Positives = 96/214 (45%), Gaps = 17/214 (8%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL-RRERGHVPMAWKMVVAQQL 718 S+++ + H ++ G C + +VTEY + G + +L RR+ VP+ + A + Sbjct 181 SMLANLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTRRQNRAVPLKLAVKQALDV 240 Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP- 777 A ++Y+ +N +H ++ N+L++ IK++D GV + E Sbjct 241 ARGMAYVHGRNFIHRDLKSDNLLIS-------ADKSIKIADFGVARIEVQTEGMTPETGT 293 Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHR-- 832 W+APE + A + +D + FG L E+ G P Q+ + + R R Sbjct 294 YRWMAPEMIQHRA--YNQKVDVYSFGIVLWEL-ITGLLPFQNMTAVQAAFAVVNRGVRPT 350 Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 +P P L+ + ++C P RP F +++ L Sbjct 351 VPNDCLPVLSDIMTRCWDANPEVRPCFVEVVKLL 384 >sp|Q9ESL4|M3K20_MOUSE Mitogen-activated protein kinase kinase kinase 20 OS=Mus musculus OX=10090 GN=Map3k20 PE=1 SV=1 Length=802 Score = 114 bits (286), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 87/282 (31%), Positives = 136/282 (48%), Gaps = 40/282 (14%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ + G G FG V Y + VAVK L ++E +IL L H Sbjct 16 LQFFENCGGGSFGSV----YRAKWISQDKEVAVKKLLK---------IEKEAEILSVLSH 62 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAY 1013 +II++ G + + +V EY LGSL DY+ + + + ++ +A + +GM Y Sbjct 63 RNIIQFYGVILE--PPNYGIVTEYASLGSLYDYINSNRSEEMDMEHIMTWATDVAKGMHY 120 Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 LH + IHRDL +RNV++ D ++KI DFG ++ V G P W AP Sbjct 121 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLV---GTFP--WMAP 175 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E ++ D +S+GV L+E+LT + P K LE + +A ++E+ Sbjct 176 EVIQSLPVSETCDTYSYGVVLWEMLT-----REVPFKGLEGLQVAWL---------VVEK 221 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 ERL P CP L+ CWE +A RP+F+ +I IL+++ Sbjct 222 NERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESM 263 Score = 62.8 bits (151), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 61/234 (26%), Positives = 104/234 (44%), Gaps = 20/234 (9%) Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWK 711 L + A ++S +SH ++ +GV + P +VTEY G L ++ R + M Sbjct 48 LKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMEHI 107 Query 712 MVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--GA 766 M A +A + YL + ++H ++ RN+++A G+ +K+ D G Sbjct 108 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV-------LKICDFGASRFHNH 160 Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + V PW+APE + + +S D + +G L E+ E P + + Sbjct 161 TTHMSLVGTFPWMAPEVIQ--SLPVSETCDTYSYGVVLWEM-LTREVPFKGLEGLQVAWL 217 Query 827 -YQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL-QPHNLAD 876 ++ RL P SCP+ A L QC + +RPSF+ I+ L + NL D Sbjct 218 VVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTNLPD 271 >sp|Q9SFB6|M3KE2_ARATH MAP3K epsilon protein kinase 2 OS=Arabidopsis thaliana OX=3702 GN=MAP3KE2 PE=2 SV=1 Length=1367 Score = 115 bits (287), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 78/269 (29%), Positives = 136/269 (51%), Gaps = 28/269 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHII 960 ++G+G +G+V Y + G+ VA+K + + G + + QEID+L+ L H++I+ Sbjct 25 EIGKGAYGRV----YIGLDLENGDFVAIKQVSLENIGQEDLNTIMQEIDLLKNLNHKNIV 80 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAYLHAQ 1017 KY G + + L +++EYV GSL + + + G + + ++ Q+ EG+ YLH Q Sbjct 81 KYLGSLKTKTH--LHIILEYVENGSLANIIKPNKFGPFPESLVTVYIAQVLEGLVYLHEQ 138 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ N+L + LVK+ DFG+A + E + +P +W APE ++ Sbjct 139 GVIHRDIKGANILTTKEGLVKLADFGVATKLNEAD--FNTHSVVGTP-YWMAPEVIELSG 195 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 ASD+WS G T+ ELLT PP L Q + R+ + + P P Sbjct 196 VCAASDIWSVGCTIIELLTCV-----PPYYDL------QPMPALYRIVQ----DDTPPIP 240 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 D ++ ++ C++ ++ RP + L+ Sbjct 241 DSLSPDITDFLRLCFKKDSRQRPDAKTLL 269 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 50/210 (24%), Positives = 87/210 (41%), Gaps = 17/210 (8%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLA 719 L+ ++H ++ G ++ EYVE+G L ++ + G P + V Q+ Sbjct 70 LLKNLNHKNIVKYLGSLKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVTVYIAQVL 129 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777 L YL + ++H ++ G NIL + GL +KL+D GV + + Sbjct 130 EGLVYLHEQGVIHRDIKGANILTTKEGL-------VKLADFGVATKLNEADFNTHSVVGT 182 Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEI--CFDGEAPLQSRSPSEKEHFYQRQHRL 833 W+APE + + + A D W G T++E+ C LQ P+ + Sbjct 183 PYWMAPEVIE--LSGVCAASDIWSVGCTIIELLTCVPPYYDLQPM-PALYRIVQDDTPPI 239 Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 P+ P + C + QRP +T+L Sbjct 240 PDSLSPDITDFLRLCFKKDSRQRPDAKTLL 269 >sp|Q9NYL2|M3K20_HUMAN Mitogen-activated protein kinase kinase kinase 20 OS=Homo sapiens OX=9606 GN=MAP3K20 PE=1 SV=3 Length=800 Score = 114 bits (285), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 87/282 (31%), Positives = 136/282 (48%), Gaps = 40/282 (14%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ + G G FG V Y + VAVK L ++E +IL L H Sbjct 16 LQFFENCGGGSFGSV----YRAKWISQDKEVAVKKLLK---------IEKEAEILSVLSH 62 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAY 1013 +II++ G + + +V EY LGSL DY+ + + + ++ +A + +GM Y Sbjct 63 RNIIQFYGVILE--PPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY 120 Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 LH + IHRDL +RNV++ D ++KI DFG ++ V G P W AP Sbjct 121 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLV---GTFP--WMAP 175 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E ++ D +S+GV L+E+LT + P K LE + +A ++E+ Sbjct 176 EVIQSLPVSETCDTYSYGVVLWEMLT-----REVPFKGLEGLQVAW---------LVVEK 221 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 ERL P CP L+ CWE +A RP+F+ +I IL+++ Sbjct 222 NERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESM 263 Score = 62.4 bits (150), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 58/226 (26%), Positives = 101/226 (45%), Gaps = 19/226 (8%) Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWK 711 L + A ++S +SH ++ +GV + P +VTEY G L ++ R + M Sbjct 48 LKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHI 107 Query 712 MVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--GA 766 M A +A + YL + ++H ++ RN+++A G+ +K+ D G Sbjct 108 MTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV-------LKICDFGASRFHNH 160 Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + V PW+APE + + +S D + +G L E+ E P + + Sbjct 161 TTHMSLVGTFPWMAPEVIQ--SLPVSETCDTYSYGVVLWEM-LTREVPFKGLEGLQVAWL 217 Query 827 -YQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 ++ RL P SCP+ A L QC + +RPSF+ I+ L + Sbjct 218 VVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESM 263 >sp|F1QVU0|LTK_DANRE Tyrosine-protein kinase receptor OS=Danio rerio OX=7955 GN=ltk PE=1 SV=1 Length=1530 Score = 115 bits (287), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 92/310 (30%), Positives = 137/310 (44%), Gaps = 44/310 (14%) Query 894 KRYLKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 ++ + +R LG G FG+V + T VA+K L C Q + E I+ Sbjct 932 RKNITLLRALGHGAFGEVYEGQVLGMNGENTAMQVAIKTLPEICSEQDEMDFLMEALIMS 991 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL-----GSLRDYL----PRHS----IGLAQ 999 H++I++ G SLQ++ ++ L G ++ +L PR + + + + Sbjct 992 KFSHQNIVRCIGV-------SLQILPRFILLELMTGGDMKSFLRLNRPRTNHSSSLSMLE 1044 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN---DRLVKIGDFGLAKAVPEGHEYYR 1056 LL A+ I G YL H+IHRD+AARN LL DR+ KIGDFG+A+ + YYR Sbjct 1045 LLHMARDIALGCRYLEENHFIHRDIAARNCLLTCPGPDRVAKIGDFGMARDIYRA-SYYR 1103 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 PV W PE E F +D WSFGV L+E+ + L + Sbjct 1104 KGGRAMLPVKWMPPEAFLEGIFTCKTDTWSFGVLLWEIFS--------------LGYMPY 1149 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 T + E + G R+ P CP VY +M CW+ RP F ++ + Y Sbjct 1150 PCKTNQEVLEFVTGGGRMDPPKSCPGPVYRIMTQCWQHCPEHRPNFTTILERI-----NY 1204 Query 1177 QGQAPSVFSV 1186 Q P V + Sbjct 1205 CTQDPDVINT 1214 Score = 70.1 bits (170), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 79/311 (25%), Positives = 128/311 (41%), Gaps = 42/311 (14%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 + +LS+L V +K IT L LG G VYEG++ M+ E+ Sbjct 920 KAASLSELK--EVPRKNITLLRALGHGAFGEVYEGQVL----------GMNGEN------ 961 Query 632 DRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 ++V +K L + + F A +MS+ SH ++ GV ++ ++ E + Sbjct 962 ---TAMQVAIKTLPEICSEQDEMDFLMEALIMSKFSHQNIVRCIGVSLQILPRFILLELM 1018 Query 691 EHGPLDVWLRRERGHVPMAWKMV------VAQQLASALSYLENKNLVHGNVCGRNILLAR 744 G + +LR R + + +A+ +A YLE + +H ++ RN LL Sbjct 1019 TGGDMKSFLRLNRPRTNHSSSLSMLELLHMARDIALGCRYLEENHFIHRDIAARNCLLT- 1077 Query 745 LGLAEGTSPFIKLSDPGVG----LGALSREERVERIP--WLAPECLPGGANSLSTAMDKW 798 G K+ D G+ + R+ +P W+ PE G + T D W Sbjct 1078 ---CPGPDRVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPPEAFLEGIFTCKT--DTW 1132 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQR 856 FG L EI G P ++ E F R+ P SCP + + +QC + P R Sbjct 1133 SFGVLLWEIFSLGYMPYPCKTNQEVLEFVTGGGRMDPPKSCPGPVYRIMTQCWQHCPEHR 1192 Query 857 PSFRTILRDLT 867 P+F TIL + Sbjct 1193 PNFTTILERIN 1203 >sp|Q91909|KIT_XENLA Mast/stem cell growth factor receptor-related protein Kit OS=Xenopus laevis OX=8355 GN=kit PE=2 SV=1 Length=954 Score = 114 bits (285), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 105/419 (25%), Positives = 177/419 (42%), Gaps = 99/419 (24%) Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS-PASDPTVFHKRYLKK 899 L + L Y+ Q+P + + + + +N + ++P P + F + L Sbjct 523 LMCIAVAVLMYKYLQKPKYEIQWKVVEEINGNNY---VYIDPTQLPYDNKWEFPRDRLCF 579 Query 900 IRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHE 957 + LG G FGKV Y + + VAVK LK R E+ +L L +H+ Sbjct 580 GKILGAGAFGKVVEATAYGLLKEDSRLTVAVKMLKPSAHSTEREALMSELKVLSYLGHHK 639 Query 958 HIIKYKG--------------CC--------------------EDQGEKSL--------- 974 +I+ G CC ED E +L Sbjct 640 NIVNLLGACTVGGPTLVITEYCCYGDLLNYLRRKRDSFICPKFEDNSEAALYKNLLNTRD 699 Query 975 ---QLVMEYVPL-----------------GSLRDY-----LPRH---SIGLAQLLLFAQQ 1006 + + EY+ + GS D +P ++ L+ F+ Q Sbjct 700 MGCEGMSEYIDMKPAVSYVVPTKTDKRRSGSFGDQDVSVSIPEEDDLALDTEDLINFSYQ 759 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 + +GM +L +++ IHRDLAARN+LL + R+ KI DFGLA+ + Y V+ + PV Sbjct 760 VAQGMNFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIRNDSNYV-VKGNARLPVK 818 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP----PTKFLELIGIAQGQMTVL 1122 W APE + + + SDVWS+G+ L+E+ + SS P +KF ++I Sbjct 819 WMAPESIFHCVYTFESDVWSYGILLWEIFS-LGSSPYPRIPVDSKFYKMI---------- 867 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 + G R+ P+ P E+Y +M++CW ++ RPTF+ ++ +++ +G P Sbjct 868 ------KDGYRMMSPECAPLEMYEIMRSCWNSDPLKRPTFKQIVQMVEQQLSDSKGNTP 920 Score = 53.1 bits (126), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 38/160 (24%), Positives = 73/160 (46%), Gaps = 20/160 (13%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 + Q+A +++L +KN +H ++ RNILL K+ D G+ + V Sbjct 757 SYQVAQGMNFLASKNCIHRDLAARNILLTH-------GRITKICDFGLARDIRNDSNYVV 809 Query 775 R------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF-- 826 + + W+APE + + + D W +G L EI G +P R P + + + Sbjct 810 KGNARLPVKWMAPESIFHCVYTFES--DVWSYGILLWEIFSLGSSPY-PRIPVDSKFYKM 866 Query 827 YQRQHRLPEPSCP--QLATLTSQCLTYEPTQRPSFRTILR 864 + +R+ P C ++ + C +P +RP+F+ I++ Sbjct 867 IKDGYRMMSPECAPLEMYEIMRSCWNSDPLKRPTFKQIVQ 906 Score = 37.7 bits (86), Expect = 0.83, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 12/74 (16%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVS-------HTHLAFVHGVCVRGPENIMVTEY 689 L V +K+L PS H E +LMS++ H ++ + G C G +++TEY Sbjct 606 LTVAVKMLKPSAHST-----EREALMSELKVLSYLGHHKNIVNLLGACTVGGPTLVITEY 660 Query 690 VEHGPLDVWLRRER 703 +G L +LRR+R Sbjct 661 CCYGDLLNYLRRKR 674 >sp|Q7T2V3|M3K10_XENLA Mitogen-activated protein kinase kinase kinase 10 OS=Xenopus laevis OX=8355 GN=map3k10 PE=1 SV=1 Length=1005 Score = 114 bits (285), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 95/294 (32%), Positives = 138/294 (47%), Gaps = 43/294 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ---HRSGWKQEIDILRTLYHEHI 959 +G G FGKV + E VAVKA++ D +QE I L H +I Sbjct 124 IGVGGFGKVYKGLW------RDEEVAVKAVRHDPDEDINVTAENVRQEAKIFCMLCHPNI 177 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I G C L LVMEY G L L + L+ +A QI +GM YLH + Sbjct 178 IALTGVC--LKPPHLCLVMEYARGGPLHRALAGKKVPAHVLVNWAVQIAKGMTYLHNEAI 235 Query 1020 ---IHRDLAARNVLL----DNDRL----VKIGDFGLAKAVPEGHEYYRVREDGDSPVF-W 1067 IHRDL + N+L+ +ND L + I DFGLA+ E+ + + + + W Sbjct 236 VPIIHRDLGSSNILILEKAENDDLFNKTLNITDFGLAR------EWQKTTKMSAAGTYAW 289 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE ++ F +SDVWSFGV L+ELLT P + ++ + +A G + + +LT Sbjct 290 MAPEVIRLSLFSKSSDVWSFGVLLWELLTG-----EVPYREIDALAVAYG-VAMNKLT-- 341 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 LP P CP +++ CW+ + RPTF ++ L T+ + Q P Sbjct 342 ------LPIPSTCPEPFVRILEACWDPDPHSRPTFSCILEQLTTIEQSAMFQMP 389 Score = 65.9 bits (159), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 69/253 (27%), Positives = 109/253 (43%), Gaps = 22/253 (9%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 RD ++ V D + A + A + + H ++ + GVC++ P +V EY Sbjct 138 RDEEVAVKAVRHDPDEDINVTAENVRQEAKIFCMLCHPNIIALTGVCLKPPHLCLVMEYA 197 Query 691 EHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKNLV---HGNVCGRNILLARL 745 GPL L ++ HV + W A Q+A ++YL N+ +V H ++ NIL+ L Sbjct 198 RGGPLHRALAGKKVPAHVLVNW----AVQIAKGMTYLHNEAIVPIIHRDLGSSNILI--L 251 Query 746 GLAEGTSPFIK-LSDPGVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800 AE F K L+ GL ++ W+APE + + S + D W F Sbjct 252 EKAENDDLFNKTLNITDFGLAREWQKTTKMSAAGTYAWMAPEVI--RLSLFSKSSDVWSF 309 Query 801 GATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRP 857 G L E+ GE P + + + LP PS CP+ + C +P RP Sbjct 310 GVLLWEL-LTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFVRILEACWDPDPHSRP 368 Query 858 SFRTILRDLTRLQ 870 +F IL LT ++ Sbjct 369 TFSCILEQLTTIE 381 >sp|Q00495|CSF1R_RAT Macrophage colony-stimulating factor 1 receptor OS=Rattus norvegicus OX=10116 GN=Csf1r PE=1 SV=1 Length=978 Score = 114 bits (284), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 62/185 (34%), Positives = 104/185 (56%), Gaps = 18/185 (10%) Query 988 DYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 D P + L LL F+ Q+ +GMA+L +++ IHRD+AARNVLL + + KIGDFGLA+ Sbjct 741 DKEPSRPLELWDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGHVAKIGDFGLARD 800 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + Y V+ + PV W APE + + SDVWS+G+ L+E+ + Sbjct 801 IMNDSNYV-VKGNARLPVKWMAPESILYCVYTVQSDVWSYGILLWEIFS----------- 848 Query 1108 FLELIGIA--QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 +G+ G + + +L++ G ++ +P P +Y +M++CW+ E + RPTF+ + Sbjct 849 ----LGLNPYPGILVNNKFYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPTFQQI 904 Query 1166 IPILK 1170 +L+ Sbjct 905 CFLLQ 909 Score = 53.9 bits (128), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 52/209 (25%), Positives = 93/209 (44%), Gaps = 35/209 (17%) Query 686 VTEYVEHGPL-----DVWLRRERGHVPM----AWKMV-VAQQLASALSYLENKNLVHGNV 735 V YVE P+ D + +++ P W ++ + Q+A +++L +KN +H +V Sbjct 718 VDTYVEMRPVSTSSSDSFFKQDLDKEPSRPLELWDLLHFSSQVAQGMAFLASKNCIHRDV 777 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGAN 789 RN+LL +A K+ D G+ ++ V + + W+APE + Sbjct 778 AARNVLLTSGHVA-------KIGDFGLARDIMNDSNYVVKGNARLPVKWMAPESILYCVY 830 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-----RQHRLPEPSCPQLATL 844 ++ + D W +G L EI G P + K FY+ Q P + + ++ Sbjct 831 TVQS--DVWSYGILLWEIFSLGLNPYPGILVNNK--FYKLVKDGYQMAQPVFAPKNIYSI 886 Query 845 TSQCLTYEPTQRPSFRTI---LRDLTRLQ 870 C EPT+RP+F+ I L++ RL+ Sbjct 887 MQSCWDLEPTRRPTFQQICFLLQEQARLE 915 >sp|P27450|CST_ARATH Probable serine/threonine-protein kinase CST OS=Arabidopsis thaliana OX=3702 GN=CST PE=1 SV=2 Length=419 Score = 110 bits (275), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 83/282 (29%), Positives = 142/282 (50%), Gaps = 15/282 (5%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LG+G FGKV D P+ G+G +VA+K L ++ Q + W+ E++ L L H Sbjct 92 LGQGGFGKVYRGWVDATTLAPSRVGSGMIVAIKRLNSES-VQGFAEWRSEVNFLGMLSHR 150 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI--CEGMAYLH 1015 +++K G C + +K L LV E++P GSL +L R + L I G+A+LH Sbjct 151 NLVKLLGYCRE--DKELLLVYEFMPKGSLESHLFRRNDPFPWDLRIKIVIGAARGLAFLH 208 Query 1016 A--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + + I+RD A N+LLD++ K+ DFGLAK P E V + APE + Sbjct 209 SLQREVIYRDFKASNILLDSNYDAKLSDFGLAKLGP-ADEKSHVTTRIMGTYGYAAPEYM 267 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVL-RLTELLERG 1131 Y SDV++FGV L E++T + + P L+ + +++ R+ +++++G Sbjct 268 ATGHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLVDWLRPELSNKHRVKQIMDKG 327 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + K E+ + +C E + RP + ++ +L+ + Sbjct 328 IKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEVLEHIQ 369 Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 72/309 (23%), Positives = 121/309 (39%), Gaps = 52/309 (17%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 S LGQG VY G + D L P R G + V +K L+ Sbjct 90 SMLGQGGFGKVYRGWV--------------DATTLAPSR-VGSGMIVAIKRLNSESVQGF 134 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 + + + +SH +L + G C E ++V E++ G L+ L R P ++ Sbjct 135 AEWRSEVNFLGMLSHRNLVKLLGYCREDKELLLVYEFMPKGSLESHLFRRNDPFPWDLRI 194 Query 713 VVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSR 769 + A L++L + + +++ + NILL ++ KLSD G+ LG Sbjct 195 KIVIGAARGLAFLHSLQREVIYRDFKASNILL-------DSNYDAKLSDFGLAKLGPADE 247 Query 770 EERV-ERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + V RI + APE + G L D + FG LLEI G ++ P +E Sbjct 248 KSHVTTRIMGTYGYAAPEYMATG--HLYVKSDVFAFGVVLLEI-MTGLTAHNTKRPRGQE 304 Query 825 HFY-------QRQHRLPE------------PSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 +HR+ + ++A +T C+ +P RP + ++ Sbjct 305 SLVDWLRPELSNKHRVKQIMDKGIKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEV 364 Query 866 LTRLQPHNL 874 L +Q N+ Sbjct 365 LEHIQGLNV 373 >sp|Q9LJD8|M3KE1_ARATH MAP3K epsilon protein kinase 1 OS=Arabidopsis thaliana OX=3702 GN=M3KE1 PE=1 SV=1 Length=1368 Score = 114 bits (285), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 79/269 (29%), Positives = 137/269 (51%), Gaps = 28/269 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHII 960 ++G+G +G+V Y + G+ VA+K + + Q + QEID+L+ L H++I+ Sbjct 25 EIGKGAYGRV----YKGLDLENGDFVAIKQVSLENIVQEDLNTIMQEIDLLKNLNHKNIV 80 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAYLHAQ 1017 KY G + + L +++EYV GSL + + + G + + ++ Q+ EG+ YLH Q Sbjct 81 KYLGSSKTKTH--LHIILEYVENGSLANIIKPNKFGPFPESLVAVYIAQVLEGLVYLHEQ 138 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ N+L + LVK+ DFG+A + E +P +W APE ++ Sbjct 139 GVIHRDIKGANILTTKEGLVKLADFGVATKLNEAD--VNTHSVVGTP-YWMAPEVIEMSG 195 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 ASD+WS G T+ ELLT C PP + +L Q + R+ + + P P Sbjct 196 VCAASDIWSVGCTVIELLT-C----VPP--YYDL----QPMPALFRIVQ----DDNPPIP 240 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 D ++ ++ C++ ++ RP + L+ Sbjct 241 DSLSPDITDFLRQCFKKDSRQRPDAKTLL 269 Score = 59.7 bits (143), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 51/210 (24%), Positives = 88/210 (42%), Gaps = 17/210 (8%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLA 719 L+ ++H ++ G ++ EYVE+G L ++ + G P + V Q+ Sbjct 70 LLKNLNHKNIVKYLGSSKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVAVYIAQVL 129 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777 L YL + ++H ++ G NIL + GL +KL+D GV + + Sbjct 130 EGLVYLHEQGVIHRDIKGANILTTKEGL-------VKLADFGVATKLNEADVNTHSVVGT 182 Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEI--CFDGEAPLQSRSPSEKEHFYQRQHRL 833 W+APE + + + A D W G T++E+ C LQ P+ + Sbjct 183 PYWMAPEVIE--MSGVCAASDIWSVGCTVIELLTCVPPYYDLQPM-PALFRIVQDDNPPI 239 Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 P+ P + QC + QRP +T+L Sbjct 240 PDSLSPDITDFLRQCFKKDSRQRPDAKTLL 269 >sp|P09581|CSF1R_MOUSE Macrophage colony-stimulating factor 1 receptor OS=Mus musculus OX=10090 GN=Csf1r PE=1 SV=3 Length=977 Score = 113 bits (283), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 60/176 (34%), Positives = 102/176 (58%), Gaps = 18/176 (10%) Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 L LL F+ Q+ +GMA+L +++ IHRD+AARNVLL + + KIGDFGLA+ + Y Sbjct 750 LWDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGHVAKIGDFGLARDIMNDSNYV- 808 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA- 1115 V+ + PV W APE + + + SDVWS+G+ L+E+ + +G+ Sbjct 809 VKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFS---------------LGLNP 853 Query 1116 -QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 G + + +L++ G ++ +P P +Y +M++CW+ E + RPTF+ + +L+ Sbjct 854 YPGILVNNKFYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPTFQQICFLLQ 909 Score = 53.9 bits (128), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 45/176 (26%), Positives = 81/176 (46%), Gaps = 26/176 (15%) Query 710 WKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 W ++ + Q+A +++L +KN +H +V RN+LL +A K+ D G+ ++ Sbjct 751 WDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGHVA-------KIGDFGLARDIMN 803 Query 769 REERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 V + + W+APE + ++ + D W +G L EI G P + Sbjct 804 DSNYVVKGNARLPVKWMAPESIFDCVYTVQS--DVWSYGILLWEIFSLGLNPYPGILVNN 861 Query 823 KEHFYQ-----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI---LRDLTRLQ 870 K FY+ Q P + + ++ C EPT+RP+F+ I L++ RL+ Sbjct 862 K--FYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPTFQQICFLLQEQARLE 915 >sp|P35968|VGFR2_HUMAN Vascular endothelial growth factor receptor 2 OS=Homo sapiens OX=9606 GN=KDR PE=1 SV=2 Length=1356 Score = 114 bits (284), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 73/197 (37%), Positives = 103/197 (52%), Gaps = 20/197 (10%) Query 971 EKSLQLVMEY-VPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029 EKSL V E P +D+L L L+ ++ Q+ +GM +L ++ IHRDLAARN+ Sbjct 980 EKSLSDVEEEEAPEDLYKDFLT-----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNI 1034 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 LL +VKI DFGLA+ + + +Y R + D P+ W APE + + + SDVWSFGV Sbjct 1035 LLSEKNVVKICDFGLARDIYKDPDYVR-KGDARLPLKWMAPETIFDRVYTIQSDVWSFGV 1093 Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149 L+E+ + +S P K E L+ G R+ PD E+Y M Sbjct 1094 LLWEIFS-LGASPYPGVKIDE------------EFCRRLKEGTRMRAPDYTTPEMYQTML 1140 Query 1150 NCWETEASFRPTFENLI 1166 +CW E S RPTF L+ Sbjct 1141 DCWHGEPSQRPTFSELV 1157 Score = 57.4 bits (137), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 50/199 (25%), Positives = 87/199 (44%), Gaps = 38/199 (19%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V + Sbjct 1011 QVAKGMEFLASRKCIHRDLAARNILLSEKNV-------VKICDFGLARDIYKDPDYVRKG 1063 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--EHFYQ 828 + W+APE + ++ + D W FG L EI G +P P K E F + Sbjct 1064 DARLPLKWMAPETIFDRVYTIQS--DVWSFGVLLWEIFSLGASPY----PGVKIDEEFCR 1117 Query 829 R-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN---------- 873 R + R P+ + P++ C EP+QRP+F ++ L L N Sbjct 1118 RLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDGKDYIV 1177 Query 874 --LADVLTVNPDSPASDPT 890 +++ L++ DS S PT Sbjct 1178 LPISETLSMEEDSGLSLPT 1196 >sp|Q8AXC6|KIT_TAKRU Mast/stem cell growth factor receptor Kit OS=Takifugu rubripes OX=31033 GN=kit PE=3 SV=1 Length=984 Score = 113 bits (283), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 58/173 (34%), Positives = 96/173 (55%), Gaps = 14/173 (8%) Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 S+ LL F+ Q+ +GM +L +++ IHRDLAARN+LL R+ KI DFGLA+ + Sbjct 752 SLDTEDLLSFSYQVAKGMEFLTSKNCIHRDLAARNILLTQGRVAKICDFGLARDINTDSN 811 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 Y V+ + PV W +PE + E + + SDVWS+G+ L+E+ + +S Sbjct 812 YV-VKGNARLPVKWMSPESIFECVYTFESDVWSYGILLWEIFSLGNSPYP---------- 860 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 G + +L++ G R+ P+ P E+Y +M++CW+ + RP F ++ Sbjct 861 ---GMPVDAKFYKLIKEGYRMDAPEFAPSEMYQIMRSCWDADPLNRPPFRKVV 910 Score = 48.1 bits (113), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 39/161 (24%), Positives = 71/161 (44%), Gaps = 22/161 (14%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L +KN +H ++ RNILL + +A K+ D G+ + V + Sbjct 764 QVAKGMEFLTSKNCIHRDLAARNILLTQGRVA-------KICDFGLARDINTDSNYVVKG 816 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--- 827 + W++PE + + + D W +G L EI G +P K FY Sbjct 817 NARLPVKWMSPESIFECVYTFES--DVWSYGILLWEIFSLGNSPYPGMPVDAK--FYKLI 872 Query 828 QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 + +R+ PE + ++ + C +P RP FR ++ + Sbjct 873 KEGYRMDAPEFAPSEMYQIMRSCWDADPLNRPPFRKVVERI 913 Score = 42.4 bits (98), Expect = 0.030, Method: Compositional matrix adjust. Identities = 38/147 (26%), Positives = 65/147 (44%), Gaps = 8/147 (5%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS-PASDPTVFHKRYLKKIRDLGEGH 907 L Y+ Q+P ++ + + + +N + ++P P F ++ L+ + LG G Sbjct 533 LFYKYMQKPKYQIQWKVIEGIHGNNY---VYIDPTQLPYDHQWEFPRKNLRFGKTLGSGA 589 Query 908 FGK-VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGC 965 FGK V Y N+ + VAVK LK+ + E+ +L L H +I+ G Sbjct 590 FGKVVEATAYGLANEDSMMTVAVKMLKSSAHSTEKEALMSELKVLIYLGNHINIVNLLGA 649 Query 966 CEDQGEKSLQLVMEYVPLGSLRDYLPR 992 C G ++ EY G L ++L R Sbjct 650 CTVGGPT--LVITEYCCFGDLLNFLRR 674 >sp|Q21041|VER4_CAEEL Tyrosine-protein kinase receptor ver-4 OS=Caenorhabditis elegans OX=6239 GN=ver-4 PE=3 SV=2 Length=1216 Score = 113 bits (283), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 72/212 (34%), Positives = 101/212 (48%), Gaps = 31/212 (15%) Query 980 YVPLGSLRDYLPRHSIGLAQLLL-------------FAQQICEGMAYLHAQHYIHRDLAA 1026 Y+ L ++R+ +P+ + QLL+ QI GM +L +HRDLA Sbjct 986 YIFLTNVRENVPKREVEKEQLLIDEFNSLCTSDLLSIGLQIANGMDWLANIPCVHRDLAC 1045 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS--PVFWYAPECLKEYKFYYASDV 1084 RNVL+ ++++I DFGLAK + YYRVRE D+ PV W E + + F SDV Sbjct 1046 RNVLISKTKIIRIADFGLAKKHTD-KAYYRVRESLDTPLPVRWMPLESITDLTFTQKSDV 1104 Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144 WS+G+ LYE+ T L G L E ++ G RP C +V Sbjct 1105 WSYGICLYEIFT--------------LGGTPYPDCPNFSLVEYIKTGNINKRPSNCHKDV 1150 Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 Y +MK CW+ RPTF I + K H +Y Sbjct 1151 YKIMKMCWQASPDDRPTFAECIKLFKN-HIQY 1181 >sp|Q8JFR5|KITA_DANRE Mast/stem cell growth factor receptor kita OS=Danio rerio OX=7955 GN=kita PE=2 SV=2 Length=976 Score = 113 bits (282), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 64/205 (31%), Positives = 107/205 (52%), Gaps = 16/205 (8%) Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYIH 1021 G + +SL Y ++ + L + L LL F+ Q+ +GM +L +++ IH Sbjct 716 GILSSENRRSLNKGDSYSDSDAVSEILQEDGLTLDTEDLLSFSYQVAKGMDFLASKNCIH 775 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RDLAARN+LL R+ KI DFGLA+ + Y V+ + PV W +PE + E + + Sbjct 776 RDLAARNILLTQGRVAKICDFGLARDITTDSNYV-VKGNARLPVKWMSPESIFECVYTFE 834 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 SDVWS+G+ L+E+ + SS P G + ++++ G R+ P+ P Sbjct 835 SDVWSYGILLWEIFS-LGSSPYP------------GMPVDSKFYKMIKEGYRMESPEFSP 881 Query 1142 CEVYHLMKNCWETEASFRPTFENLI 1166 E+Y +M +CW+ + RP+F ++ Sbjct 882 SEMYDIMHSCWDADPVKRPSFSKIV 906 Score = 51.6 bits (122), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 41/161 (25%), Positives = 72/161 (45%), Gaps = 22/161 (14%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L +KN +H ++ RNILL + +A K+ D G+ + V + Sbjct 760 QVAKGMDFLASKNCIHRDLAARNILLTQGRVA-------KICDFGLARDITTDSNYVVKG 812 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--- 827 + W++PE + + + D W +G L EI G +P K FY Sbjct 813 NARLPVKWMSPESIFECVYTFES--DVWSYGILLWEIFSLGSSPYPGMPVDSK--FYKMI 868 Query 828 QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 + +R+ PE S ++ + C +P +RPSF I+ + Sbjct 869 KEGYRMESPEFSPSEMYDIMHSCWDADPVKRPSFSKIVEKI 909 Score = 34.7 bits (78), Expect = 6.3, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 12/74 (16%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQV-------SHTHLAFVHGVCVRGPENIMVTEY 689 + V +K+L PS H E +LMS++ +H ++ + G C G +++TEY Sbjct 609 MTVAVKMLKPSAHAT-----EKEALMSELKVLSYLGNHINIVNLLGACTVGGPTLVITEY 663 Query 690 VEHGPLDVWLRRER 703 G L +LRR R Sbjct 664 CCFGDLLNFLRRRR 677 >sp|Q8UVR8|CSF12_TAKRU Macrophage colony-stimulating factor 1 receptor 2 OS=Takifugu rubripes OX=31033 GN=csf1r2 PE=3 SV=1 Length=1019 Score = 113 bits (282), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 61/178 (34%), Positives = 99/178 (56%), Gaps = 20/178 (11%) Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + LL F+ Q+ +G+ +L ++ IHRD+AARNVLL + R+ KI DFGLA+ + + + Sbjct 799 LSFGDLLSFSHQVAQGLDFLSTRNCIHRDVAARNVLLTDHRVAKICDFGLARDI-QNDDS 857 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS---SQSPPTKFLEL 1111 Y V+ + PV W APE + + + SDVWS+GV L+E+ + S + + T F ++ Sbjct 858 YIVQGNARLPVKWMAPESIFQCVYTVQSDVWSYGVLLWEIFSLGKSPYPNVAVDTHFYKM 917 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 I + G + +PD P E+Y LM +CW E + RPTF+ + ++ Sbjct 918 I----------------KDGRHMTQPDFAPVEMYQLMTHCWSLEPTDRPTFKMICQLI 959 Score = 62.8 bits (151), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 46/170 (27%), Positives = 81/170 (48%), Gaps = 22/170 (13%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV- 773 + Q+A L +L +N +H +V RN+LL +A K+ D G+ + + + Sbjct 808 SHQVAQGLDFLSTRNCIHRDVAARNVLLTDHRVA-------KICDFGLARDIQNDDSYIV 860 Query 774 ---ERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 R+P W+APE + ++ + D W +G L EI G++P + + HFY+ Sbjct 861 QGNARLPVKWMAPESIFQCVYTVQS--DVWSYGVLLWEIFSLGKSPYPNVAV--DTHFYK 916 Query 829 -----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 R P+ + ++ L + C + EPT RP+F+ I + + RL N Sbjct 917 MIKDGRHMTQPDFAPVEMYQLMTHCWSLEPTDRPTFKMICQLIDRLLQSN 966 >sp|Q5XJV6|LMTK3_MOUSE Serine/threonine-protein kinase LMTK3 OS=Mus musculus OX=10090 GN=Lmtk3 PE=1 SV=1 Length=1424 Score = 113 bits (282), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 79/232 (34%), Positives = 116/232 (50%), Gaps = 23/232 (10%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 P S S P +++L ++++G G FGKV L +D + V VK L+A GP + Sbjct 118 PHSDISTPLGLSRQHLSYLQEIGSGWFGKVILGEV--FSDYSPAQVVVKELRASAGPLEQ 175 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIG- 996 + E R+L H ++++ G C + L+ME+ LG L+ YL P + Sbjct 176 RKFISEAQPYRSLQHPNVLQCLGVCVET--LPFLLIMEFCQLGDLKRYLRAQRPPEGMSP 233 Query 997 ------LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 L L +I G+A+LH+ +Y+H DLA RN LL +D V+IGD+GLA + Sbjct 234 ELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSN-Y 292 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYA-------SDVWSFGVTLYELL 1095 +YY E P+ W APE L E + S+VWS GVTL+EL Sbjct 293 KEDYYLTPERLWVPLRWAAPELLGELHGSFVLVDQSRESNVWSLGVTLWELF 344 Score = 38.9 bits (89), Expect = 0.35, Method: Compositional matrix adjust. Identities = 60/244 (25%), Positives = 92/244 (38%), Gaps = 39/244 (16%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV- 713 F A + H ++ GVCV +++ E+ + G L +LR +R M+ ++ Sbjct 178 FISEAQPYRSLQHPNVLQCLGVCVETLPFLLIMEFCQLGDLKRYLRAQRPPEGMSPELPP 237 Query 714 --------VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 + ++A L++L + N VH ++ RN LL + +++ D GL Sbjct 238 RDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLT-------SDLTVRIGD--YGLA 288 Query 766 ALSREERVERIP--------WLAPECLPGGANSL-----STAMDKWGFGATLLEICFDGE 812 + +E P W APE L S S + W G TL E+ G Sbjct 289 HSNYKEDYYLTPERLWVPLRWAAPELLGELHGSFVLVDQSRESNVWSLGVTLWELFEFGA 348 Query 813 APLQSRSPSEKEHFYQRQH-------RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 P + S E F RQ RL P + C P QRPS + Sbjct 349 QPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCW-RPPAQRPSASDLQLQ 407 Query 866 LTRL 869 LT L Sbjct 408 LTYL 411 >sp|A0A078CGE6|M3KE1_BRANA MAP3K epsilon protein kinase 1 OS=Brassica napus OX=3708 GN=M3KE1 PE=1 SV=1 Length=1299 Score = 113 bits (282), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 79/269 (29%), Positives = 135/269 (50%), Gaps = 28/269 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHII 960 ++G+G +G+V Y + G+ VA+K + + Q + QEID+L+ L H++I+ Sbjct 25 EIGKGAYGRV----YIGLDLENGDFVAIKQVSLENIVQEDLNTIMQEIDLLKNLNHKNIV 80 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAYLHAQ 1017 KY G + + L +++EYV GSL + + + G + + ++ Q+ EG+ YLH Q Sbjct 81 KYLGSLKTKTH--LHIILEYVENGSLANIIKPNKFGPFPESLVTVYIAQVLEGLVYLHEQ 138 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ N+L + LVK+ DFG+A + E +P +W APE ++ Sbjct 139 GVIHRDIKGANILTTKEGLVKLADFGVATKLNEAD--VNTHSVVGTP-YWMAPEVIEMSG 195 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 ASD+WS G T+ ELLT C PP L Q + R+ + + P P Sbjct 196 VCAASDIWSVGCTVIELLT-C----VPPYYDL------QPMPALFRIVQ----DDSPPIP 240 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 D ++ ++ C++ ++ RP + L+ Sbjct 241 DSLSPDITDFLRQCFKKDSRQRPDAKTLL 269 Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 51/210 (24%), Positives = 88/210 (42%), Gaps = 17/210 (8%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLA 719 L+ ++H ++ G ++ EYVE+G L ++ + G P + V Q+ Sbjct 70 LLKNLNHKNIVKYLGSLKTKTHLHIILEYVENGSLANIIKPNKFGPFPESLVTVYIAQVL 129 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777 L YL + ++H ++ G NIL + GL +KL+D GV + + Sbjct 130 EGLVYLHEQGVIHRDIKGANILTTKEGL-------VKLADFGVATKLNEADVNTHSVVGT 182 Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEI--CFDGEAPLQSRSPSEKEHFYQRQHRL 833 W+APE + + + A D W G T++E+ C LQ P+ + Sbjct 183 PYWMAPEVIE--MSGVCAASDIWSVGCTVIELLTCVPPYYDLQPM-PALFRIVQDDSPPI 239 Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 P+ P + QC + QRP +T+L Sbjct 240 PDSLSPDITDFLRQCFKKDSRQRPDAKTLL 269 >sp|P34891|KIN15_CAEEL Receptor-like tyrosine-protein kinase kin-15 OS=Caenorhabditis elegans OX=6239 GN=kin-15 PE=2 SV=1 Length=488 Score = 110 bits (274), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 63/179 (35%), Positives = 99/179 (55%), Gaps = 17/179 (9%) Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 S+ + LL F+ QI EGM YL + +HRDLA RNVLL+ ++ ++I DFGLA+ + Sbjct 290 SLCTSDLLSFSYQIAEGMEYLASIPCVHRDLALRNVLLNKNKTIRIADFGLARKY-QVDG 348 Query 1054 YYRVREDGDSPV--FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111 YYR+ + +P+ W APE ++E K SDVWS+GV+LYE+ + L Sbjct 349 YYRITKGVGTPMPARWMAPEVMREGKCTEKSDVWSYGVSLYEMFS--------------L 394 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + ++ + E + +G +LP P C ++Y MK W +A+FRP+F + + Sbjct 395 GELPYSNVSNSDVFEHVVQGNQLPMPQYCHPKMYDRMKQFWNFDATFRPSFSKCVEFFE 453 Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 66/297 (22%), Positives = 123/297 (41%), Gaps = 43/297 (14%) Query 592 LSHLGQGTRTNVYEG-RLRVEGSGDP----EEGKMDDEDPLVPGRDRGQELRVVLKVLD- 645 LS T T+ + + V+ S DP +E ++DE L+ R + ++ + Sbjct 163 LSMRTSNTETDTLQKLSVAVKQSNDPTQENQEKMIEDETKLMCAIGRNPNILAIIGAVTA 222 Query 646 ---PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDV 697 + + + + F E L+ + F + P++I Y+ + D Sbjct 223 NSGSARNLLIVEFVECGDLLKFLEEKKSIFKDELVYEKNGYLLPKSIRRKTYMFNENEDD 282 Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + + + + + Q+A + YL + VH ++ RN+LL + + I++ Sbjct 283 VIEESLDSLCTSDLLSFSYQIAEGMEYLASIPCVHRDLALRNVLLNK-------NKTIRI 335 Query 758 SDPGVGLGALSREERVE---RIP----------WLAPECLPGGANSLSTAMDKWGFGATL 804 +D G L+R+ +V+ RI W+APE + G + D W +G +L Sbjct 336 ADFG-----LARKYQVDGYYRITKGVGTPMPARWMAPEVMREGK--CTEKSDVWSYGVSL 388 Query 805 LEICFDGEAPLQSRSPSEK-EHFYQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859 E+ GE P + S S+ EH Q Q +P+ P++ Q ++ T RPSF Sbjct 389 YEMFSLGELPYSNVSNSDVFEHVVQGNQLPMPQYCHPKMYDRMKQFWNFDATFRPSF 445 >sp|Q9SSA4|CBC1_ARATH Serine/threonine-protein kinase 54 OS=Arabidopsis thaliana OX=3702 GN=CBC1 PE=1 SV=1 Length=411 Score = 108 bits (271), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 83/304 (27%), Positives = 134/304 (44%), Gaps = 54/304 (18%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ-HRS---------GWKQEIDILR 952 + G FG V YD G+ VAVK L D G + HRS + QE+ + Sbjct 114 IARGTFGTVHRGIYD------GQDVAVKLL--DWGEEGHRSDAEIASLRAAFTQEVAVWH 165 Query 953 TLYHEHIIKYKGCCEDQGEKSLQ--------------LVMEYVPLGSLRDYL---PRHSI 995 L H ++ K+ G E S+Q +V+EY P G+L+ +L R + Sbjct 166 KLDHPNVTKFIGAAMGTSEMSIQTENGQMGMPSNVCCVVVEYCPGGALKSFLIKTRRRKL 225 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 ++ + + G++YLH+Q +HRD+ N+LLD R +KI DFG+A+ Sbjct 226 AFKVVIQLSLDLARGLSYLHSQKIVHRDVKTENMLLDKSRTLKIADFGVARLEASNPNDM 285 Query 1056 RVREDGDSPVFWY-APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 G++ Y APE L + DV+SFG+ L+E+ +C P F E+ Sbjct 286 ----TGETGTLGYMAPEVLNGSPYNRKCDVYSFGICLWEI--YCCDMPYPDLSFSEVT-- 337 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + ++ + R P CP + ++MK CW+ RP E ++ +L+ + Sbjct 338 ----------SAVVRQNLRPEIPRCCPSSLANVMKRCWDANPEKRPEMEEVVAMLEAIDT 387 Query 1175 KYQG 1178 G Sbjct 388 SKGG 391 Score = 59.7 bits (143), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 67/239 (28%), Positives = 104/239 (44%), Gaps = 28/239 (12%) Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 QE+ V K+ P+ A T+ + Q + + VC +V EY G Sbjct 159 QEVAVWHKLDHPNVTKFIGAAMGTSEMSIQTENGQMGMPSNVCC------VVVEYCPGGA 212 Query 695 LDVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752 L +L + R +A+K+V+ + LA LSYL ++ +VH +V N+LL + S Sbjct 213 LKSFLIKTR-RRKLAFKVVIQLSLDLARGLSYLHSQKIVHRDVKTENMLLDK-------S 264 Query 753 PFIKLSDPGVGLGALSREERVE----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI- 807 +K++D GV S + + ++APE L G + + D + FG L EI Sbjct 265 RTLKIADFGVARLEASNPNDMTGETGTLGYMAPEVLNG--SPYNRKCDVYSFGICLWEIY 322 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSC--PQLATLTSQCLTYEPTQRPSFRTIL 863 C D P S SE RQ+ PE P C LA + +C P +RP ++ Sbjct 323 CCD--MPYPDLSFSEVTSAVVRQNLRPEIPRCCPSSLANVMKRCWDANPEKRPEMEEVV 379 >sp|Q65XV8|RK176_ORYSJ Receptor-like cytoplasmic kinase 176 OS=Oryza sativa subsp. japonica OX=39947 GN=RLCK176 PE=1 SV=1 Length=395 Score = 108 bits (269), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 97/301 (32%), Positives = 143/301 (48%), Gaps = 29/301 (10%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LGEG FG V D PT GTG ++AVK L + HR W E++ L L H Sbjct 76 LGEGGFGSVFKGWIDEKTLAPTKPGTGMVIAVKKLNQEGHQGHRE-WLAEVNYLGQLSHP 134 Query 958 HIIKYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGM 1011 ++++ G C ED E+ L LV E++P GSL ++L R S L + A +G+ Sbjct 135 YLVRLVGYCVED--EQRL-LVYEFMPRGSLENHLFRRSTHFQPLSWNLRMKIALGAAKGL 191 Query 1012 AYLHAQHY--IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 A+LH+ I+RD NVLLD + K+ DFGLAK P G + + V + A Sbjct 192 AFLHSDKVKVIYRDFKTSNVLLDANYDAKLSDFGLAKDGPTGDKSH-VSTRVMGTYGYAA 250 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQ----GQMTVLRL 1124 PE L SDV+SFGV L E+L+ + ++ PT L+ A+ + + R+ Sbjct 251 PEYLATGHLTTKSDVYSFGVVLLEMLSGRRALDKNRPTGEHNLVEWARPYLMSKRRIFRI 310 Query 1125 TELLERGE-RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE-KYQGQAPS 1182 + G+ L + K L C EA RP E ++ +L+ + + K G P Sbjct 311 LDARLGGQYSLAKAQKAAT----LALQCISVEAKNRPNMEQVVAVLEQLQDSKETGANPQ 366 Query 1183 V 1183 + Sbjct 367 L 367 Score = 62.0 bits (149), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 75/322 (23%), Positives = 133/322 (41%), Gaps = 45/322 (14%) Query 575 NLSQLSFH--RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 N+ +F+ R + S LG+G +V++G + DE L P + Sbjct 54 NVKAFAFNELRTATRNFRPDSVLGEGGFGSVFKGWI--------------DEKTLAPTKP 99 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 G + + +K L+ H + + + Q+SH +L + G CV + ++V E++ Sbjct 100 -GTGMVIAVKKLNQEGHQGHREWLAEVNYLGQLSHPYLVRLVGYCVEDEQRLLVYEFMPR 158 Query 693 GPLDVWLRRERGHV-PMAW--KMVVAQQLASALSYL--ENKNLVHGNVCGRNILLARLGL 747 G L+ L R H P++W +M +A A L++L + +++ + N+LL Sbjct 159 GSLENHLFRRSTHFQPLSWNLRMKIALGAAKGLAFLHSDKVKVIYRDFKTSNVLLDANYD 218 Query 748 AEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 A+ S F D G + + + APE L G L+T D + FG LLE+ Sbjct 219 AK-LSDFGLAKDGPTGDKSHVSTRVMGTYGYAAPEYLATG--HLTTKSDVYSFGVVLLEM 275 Query 808 CFDGEAPLQSRSPSEKEHFYQ----------RQHRLPE---------PSCPQLATLTSQC 848 G L P+ + + + R R+ + + ATL QC Sbjct 276 -LSGRRALDKNRPTGEHNLVEWARPYLMSKRRIFRILDARLGGQYSLAKAQKAATLALQC 334 Query 849 LTYEPTQRPSFRTILRDLTRLQ 870 ++ E RP+ ++ L +LQ Sbjct 335 ISVEAKNRPNMEQVVAVLEQLQ 356 >sp|Q54R82|MKKA_DICDI Mitogen-activated protein kinase kinase kinase A OS=Dictyostelium discoideum OX=44689 GN=mkkA PE=1 SV=2 Length=942 Score = 112 bits (279), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 79/295 (27%), Positives = 144/295 (49%), Gaps = 33/295 (11%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA---DCGPQHRS---GWKQ 946 H +K + LG G +G V Y N TGE+ AVK L+ + P+ ++ + + Sbjct 166 HNIKWQKGQILGRGGYGSV----YLGLNKDTGELFAVKQLEIVDINSDPKLKNMILSFSK 221 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL-LFAQ 1005 EI+++R+L H++I++Y G DQ L + +EY+P GS+ L + ++ ++ + Sbjct 222 EIEVMRSLRHDNIVRYLGTSLDQS--FLSVFLEYIPGGSISSLLGKFGAFSENVIKVYTK 279 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 QI +G+++LHA IHRD+ N+L+D +VK+ DFG +K+ ++ + +P Sbjct 280 QILQGLSFLHANSIIHRDIKGANILIDTKGIVKLSDFGCSKSFSGIVSQFKSMQ--GTP- 336 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 +W APE +K+ +SD+WS G + E+ T +Q P + EL + Sbjct 337 YWMAPEVIKQTGHGRSSDIWSLGCVIVEMAT----AQPPWSNITELAAVMYH-------- 384 Query 1126 ELLERGERLPR-PDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQ 1177 + +P P E + + C++ + RP L+ P + + + Q Sbjct 385 --IASSNSIPNIPSHMSQEAFDFLNLCFKRDPKERPDANQLLKHPFIMNLDDNIQ 437 Score = 54.7 bits (130), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 55/242 (23%), Positives = 101/242 (42%), Gaps = 27/242 (11%) Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 ++L +V DP ++ L+F + +M + H ++ G + + EY+ G Sbjct 199 KQLEIVDINSDPKLKNMILSFSKEIEVMRSLRHDNIVRYLGTSLDQSFLSVFLEYIPGGS 258 Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 + L + K V +Q+ LS+L +++H ++ G NIL+ G+ Sbjct 259 ISSLLGKFGAFSENVIK-VYTKQILQGLSFLHANSIIHRDIKGANILIDTKGI------- 310 Query 755 IKLSDPGVGL---GALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +KLSD G G +S+ + ++ P W+APE + + S+ D W G ++E+ Sbjct 311 VKLSDFGCSKSFSGIVSQFKSMQGTPYWMAPEVIKQTGHGRSS--DIWSLGCVIVEM--- 365 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ--------CLTYEPTQRPSFRTI 862 A Q + E H S P + + SQ C +P +RP + Sbjct 366 --ATAQPPWSNITELAAVMYHIASSNSIPNIPSHMSQEAFDFLNLCFKRDPKERPDANQL 423 Query 863 LR 864 L+ Sbjct 424 LK 425 >sp|F4HRJ4|M3K3A_ARATH Mitogen-activated protein kinase kinase kinase 3 OS=Arabidopsis thaliana OX=3702 GN=MAPKKK3 PE=1 SV=1 Length=609 Score = 110 bits (275), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 84/295 (28%), Positives = 141/295 (48%), Gaps = 32/295 (11%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS----GWKQEIDILRT 953 KK + LG G FG+V Y N G+M A+K +K Q QEI++L Sbjct 215 KKGKFLGSGTFGQV----YLGFNSEKGKMCAIKEVKVISDDQTSKECLKQLNQEINLLNQ 270 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012 L H +I++Y G + E++L + +EYV GS+ L + S + + +QI G+A Sbjct 271 LCHPNIVQYYG--SELSEETLSVYLEYVSGGSIHKLLKDYGSFTEPVIQNYTRQILAGLA 328 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE- 1071 YLH ++ +HRD+ N+L+D + +K+ DFG+AK V + + SP +W APE Sbjct 329 YLHGRNTVHRDIKGANILVDPNGEIKLADFGMAKHV---TAFSTMLSFKGSP-YWMAPEV 384 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + + +A D+WS G T+ E+ T S+ P ++F +G + ++ + Sbjct 385 VMSQNGYTHAVDIWSLGCTILEMAT----SKPPWSQF-------EGVAAIFKIGNSKDTP 433 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAPSVF 1184 E PD + + ++ C + + RPT L+ P L+ P F Sbjct 434 E---IPDHLSNDAKNFIRLCLQRNPTVRPTASQLLEHPFLRNTTRVASTSLPKDF 485 Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 72/296 (24%), Positives = 121/296 (41%), Gaps = 50/296 (17%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LG GT VY G + E+GKM +E++V+ D + + Sbjct 220 LGSGTFGQVYLGF-------NSEKGKMCAI----------KEVKVISD--DQTSKECLKQ 260 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 + +L++Q+ H ++ +G + + EYV G + L+ + G Sbjct 261 LNQEINLLNQLCHPNIVQYYGSELSEETLSVYLEYVSGGSIHKLLK-DYGSFTEPVIQNY 319 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREER 772 +Q+ + L+YL +N VH ++ G NIL+ G IKL+D G+ + A S Sbjct 320 TRQILAGLAYLHGRNTVHRDIKGANILVDPNGE-------IKLADFGMAKHVTAFSTMLS 372 Query 773 VERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEIC--------FDGEAPLQSRSPSEK 823 + P W+APE + N + A+D W G T+LE+ F+G A + S+ Sbjct 373 FKGSPYWMAPEVV-MSQNGYTHAVDIWSLGCTILEMATSKPPWSQFEGVAAIFKIGNSKD 431 Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI-----LRDLTRLQPHNL 874 +P+ CL PT RP+ + LR+ TR+ +L Sbjct 432 ------TPEIPDHLSNDAKNFIRLCLQRNPTVRPTASQLLEHPFLRNTTRVASTSL 481 >sp|Q95UN8|M3KSL_DROME Mitogen-activated protein kinase kinase kinase OS=Drosophila melanogaster OX=7227 GN=slpr PE=1 SV=1 Length=1161 Score = 112 bits (279), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 95/284 (33%), Positives = 129/284 (45%), Gaps = 43/284 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVK---ALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G G F KV YD GE VA+K D + R QE + L HE+I Sbjct 148 IGSGGFCKVHRGYYD------GEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWALKHENI 201 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 +G C + L LVMEY GSL L I L+ +A QI GM YLH + Sbjct 202 AALRGVCLN---TKLCLVMEYARGGSLNRILA-GKIPPDVLVNWAIQIARGMNYLHNEAP 257 Query 1018 -HYIHRDLAARNVLLD--------NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 IHRDL + NVL+ + +KI DFGLA+ + Y R W Sbjct 258 MSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREM-----YNTQRMSAAGTYAWM 312 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE + + SDVWS+GV L+EL+T P K + + +A G + V LT Sbjct 313 PPEVISVSTYSKFSDVWSYGVLLWELIT-----GETPYKGFDPLSVAYG-VAVNTLT--- 363 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 LP P CP LMK+CW+T+ RP F+ ++ L+++ Sbjct 364 -----LPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESI 402 >sp|Q8AXB3|VGFR4_DANRE Vascular endothelial growth factor receptor kdr-like OS=Danio rerio OX=7955 GN=kdrl PE=1 SV=1 Length=1302 Score = 111 bits (278), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 65/177 (37%), Positives = 98/177 (55%), Gaps = 14/177 (8%) Query 990 LPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 L + + L L+ ++ Q+ +GM +L ++ IHRDLAARN+LL + +VKI DFGLA+ V Sbjct 970 LYKKVLTLEDLICYSFQVAKGMEFLASRKCIHRDLAARNILLSENNVVKICDFGLARDVY 1029 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 + +Y R + D P+ W APE + + + SDVWSFGV ++E+ + +S P Sbjct 1030 KDPDYVR-KGDARLPLKWMAPEAIFDKIYTTQSDVWSFGVLMWEIFS-LGASPYP----- 1082 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 G+ + RL E G R+ P+ E+Y M +CW E S RPTF L+ Sbjct 1083 ---GLHIDEEFCCRLKE----GTRMKAPEYSSSEIYQTMLDCWHGEPSQRPTFTELV 1132 Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 41/164 (25%), Positives = 71/164 (43%), Gaps = 22/164 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V + Sbjct 986 QVAKGMEFLASRKCIHRDLAARNILLSENNV-------VKICDFGLARDVYKDPDYVRKG 1038 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + +T D W FG + EI G +P E+ F R Sbjct 1039 DARLPLKWMAPEAIFDKI--YTTQSDVWSFGVLMWEIFSLGASPYPGLHIDEE--FCCRL 1094 Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + PE S ++ C EP+QRP+F ++ L L Sbjct 1095 KEGTRMKAPEYSSSEIYQTMLDCWHGEPSQRPTFTELVERLGDL 1138 >sp|Q0CL79|SEPH_ASPTN Cytokinesis protein sepH OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=sepH PE=3 SV=2 Length=1342 Score = 111 bits (278), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 73/199 (37%), Positives = 104/199 (52%), Gaps = 24/199 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V Y N TGE VAVK +K P +S + EID+L+ L H +I+KY Sbjct 67 LGKGAFGSV----YRALNWNTGETVAVKQIKLADLP--KSELRLEIDLLKNLDHPNIVKY 120 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDY------LPRHSIGLAQLLLFAQQICEGMAYLHA 1016 +G + ++L +++EY GSL P + +GL + Q+ G+ YLH Sbjct 121 QGFV--KSAETLNIILEYCENGSLHSIAKNFGRFPENLVGL-----YMSQVLHGLLYLHE 173 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 Q IHRD+ N+L + LVK+ DFG+A E V +P +W APE ++ Sbjct 174 QGVIHRDIKGANILTTKEGLVKLADFGVASRTTGLSESSVV----GTP-YWMAPEVIELS 228 Query 1077 KFYYASDVWSFGVTLYELL 1095 ASD+WS G T+ ELL Sbjct 229 GATTASDIWSLGCTVIELL 247 Score = 63.2 bits (152), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 56/209 (27%), Positives = 90/209 (43%), Gaps = 17/209 (8%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 L+ + H ++ G ++ EY E+G L + + G P + Q+ Sbjct 108 LLKNLDHPNIVKYQGFVKSAETLNIILEYCENGSLHS-IAKNFGRFPENLVGLYMSQVLH 166 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIPW 778 L YL + ++H ++ G NIL + GL +KL+D GV LS V W Sbjct 167 GLLYLHEQGVIHRDIKGANILTTKEGL-------VKLADFGVASRTTGLSESSVVGTPYW 219 Query 779 LAPECLP-GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQH-RLPE 835 +APE + GA +TA D W G T++E+ +G+ P + P H LP+ Sbjct 220 MAPEVIELSGA---TTASDIWSLGCTVIEL-LEGKPPYYNMQPMPALFRIVNDDHPPLPQ 275 Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + P + QC +P R S R +L+ Sbjct 276 GASPAVKDFLMQCFQKDPNLRVSARKLLK 304 >sp|Q9FZ36|M3K2_ARATH Mitogen-activated protein kinase kinase kinase 2 OS=Arabidopsis thaliana OX=3702 GN=ANP2 PE=2 SV=1 Length=651 Score = 110 bits (275), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 77/294 (26%), Positives = 145/294 (49%), Gaps = 32/294 (11%) Query 884 SPASDPTVFHKRYLK--KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA--LKADCGPQ 939 SP ++ TV K ++ K + +G G FG V Y N +GE++AVK + ++C + Sbjct 53 SPPNNSTVQIKPPIRWRKGQLIGRGAFGTV----YMGMNLDSGELLAVKQVLITSNCASK 108 Query 940 HRSG-----WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993 ++ ++E+ +L+ L H +I++Y G + +++L +++E+VP GS+ L + Sbjct 109 EKTQAHIQELEEEVKLLKNLSHPNIVRYLGTVRE--DETLNILLEFVPGGSISSLLEKFG 166 Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + + + + Q+ G+ YLH +HRD+ N+L+DN +K+ DFG +K V E Sbjct 167 AFPESVVRTYTNQLLLGLEYLHNHAIMHRDIKGANILVDNQGCIKLADFGASKQVAELAT 226 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELI 1112 + +P +W APE + + +++D+WS G T+ E++T ++P ++ E+ Sbjct 227 ISGAKSMKGTP-YWMAPEVILQTGHSFSADIWSVGCTVIEMVT----GKAPWSQQYKEIA 281 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 I T P PD + + C + E + RPT L+ Sbjct 282 AIFHIGTT----------KSHPPIPDNISSDANDFLLKCLQQEPNLRPTASELL 325 Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 58/219 (26%), Positives = 95/219 (43%), Gaps = 23/219 (11%) Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715 E L+ +SH ++ G VR E + ++ E+V G + L + G P + Sbjct 120 EEVKLLKNLSHPNIVRYLGT-VREDETLNILLEFVPGGSISSLLEK-FGAFPESVVRTYT 177 Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-----LGALSRE 770 QL L YL N ++H ++ G NIL+ G IKL+D G L +S Sbjct 178 NQLLLGLEYLHNHAIMHRDIKGANILVDNQGC-------IKLADFGASKQVAELATISGA 230 Query 771 ERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-- 827 + ++ P W+APE + +S S D W G T++E+ G+AP + F+ Sbjct 231 KSMKGTPYWMAPEVILQTGHSFSA--DIWSVGCTVIEM-VTGKAPWSQQYKEIAAIFHIG 287 Query 828 -QRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + H +P+ +CL EP RP+ +L+ Sbjct 288 TTKSHPPIPDNISSDANDFLLKCLQQEPNLRPTASELLK 326 >sp|Q61083|M3K2_MOUSE Mitogen-activated protein kinase kinase kinase 2 OS=Mus musculus OX=10090 GN=Map3k2 PE=1 SV=2 Length=619 Score = 110 bits (274), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 67/201 (33%), Positives = 106/201 (53%), Gaps = 13/201 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ------EIDILRTLYH 956 LG+G FG+V L CYD TG +AVK ++ + P+ K+ EI +L+ L H Sbjct 362 LGQGAFGRVYL-CYDV---DTGRELAVKQVQFN--PESPETSKEVNALECEIQLLKNLLH 415 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL-LFAQQICEGMAYLH 1015 E I++Y GC D EK+L + ME P GS++D L + + + +QI EG+ YLH Sbjct 416 ERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLH 475 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + +HRD+ N+L D+ +K+GDFG +K + + +W +PE + Sbjct 476 SNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISG 535 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 + +D+WS T+ E+LT Sbjct 536 EGYGRKADIWSVACTVVEMLT 556 Score = 34.7 bits (78), Expect = 6.4, Method: Compositional matrix adjust. Identities = 43/192 (22%), Positives = 75/192 (39%), Gaps = 30/192 (16%) Query 632 DRGQELRVVLKVLDPSHHDIAL---AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 D G+EL V +P + + A L+ + H + +G C+R P+ ++ Sbjct 377 DTGRELAVKQVQFNPESPETSKEVNALECEIQLLKNLLHERIVQYYG-CLRDPQEKTLSI 435 Query 689 YVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 ++E P + + + + + +Q+ + YL + +VH ++ G NIL G Sbjct 436 FMELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTG 495 Query 747 LAEGTSPFIKLSDPGV----------GLGALSREERVERIP-WLAPECLPGGANSLSTAM 795 IKL D G G G S V P W++PE + G Sbjct 496 -------NIKLGDFGASKRLQTICLSGTGMKS----VTGTPYWMSPEVISG--EGYGRKA 542 Query 796 DKWGFGATLLEI 807 D W T++E+ Sbjct 543 DIWSVACTVVEM 554 >sp|Q96Q04|LMTK3_HUMAN Serine/threonine-protein kinase LMTK3 OS=Homo sapiens OX=9606 GN=LMTK3 PE=1 SV=2 Length=1460 Score = 111 bits (278), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 77/227 (34%), Positives = 115/227 (51%), Gaps = 23/227 (10%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 + P +++L ++++G G FGKV L +D T V VK L+A GP + + Sbjct 123 TTPLGLSRQHLSYLQEIGSGWFGKVILGEI--FSDYTPAQVVVKELRASAGPLEQRKFIS 180 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLA------ 998 E R+L H ++++ G C + L+ME+ LG L+ YL R GL+ Sbjct 181 EAQPYRSLQHPNVLQCLGLCVET--LPFLLIMEFCQLGDLKRYLRAQRPPEGLSPELPPR 238 Query 999 ---QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 L +I G+A+LH+ +Y+H DLA RN LL +D V+IGD+GLA + +YY Sbjct 239 DLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSN-YKEDYY 297 Query 1056 RVREDGDSPVFWYAPECLKEYKFYY-------ASDVWSFGVTLYELL 1095 E P+ W APE L E + S++WS GVTL+EL Sbjct 298 LTPERLWIPLRWAAPELLGELHGTFMVVDQSRESNIWSLGVTLWELF 344 Score = 37.0 bits (84), Expect = 1.5, Method: Compositional matrix adjust. Identities = 63/263 (24%), Positives = 102/263 (39%), Gaps = 42/263 (16%) Query 638 RVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +VV+K L S + F A + H ++ G+CV +++ E+ + G L Sbjct 160 QVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLK 219 Query 697 VWLRRERGHVPMAWKMV---------VAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 +LR +R ++ ++ + ++A L++L + N VH ++ RN LL Sbjct 220 RYLRAQRPPEGLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLT---- 275 Query 748 AEGTSPFIKLSDPGVGLGALSREERVERIP--------WLAPECLPGGANSLSTAMDK-- 797 + +++ D GL + +E P W APE L G + +D+ Sbjct 276 ---SDLTVRIGD--YGLAHSNYKEDYYLTPERLWIPLRWAAPELL-GELHGTFMVVDQSR 329 Query 798 ----WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH-------RLPEPSCPQLATLTS 846 W G TL E+ G P + S E F RQ RL P + Sbjct 330 ESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQ 389 Query 847 QCLTYEPTQRPSFRTILRDLTRL 869 C P QRPS + LT L Sbjct 390 SCW-RPPAQRPSASDLQLQLTYL 411 >sp|Q54Y55|SHKC_DICDI Dual specificity protein kinase shkC OS=Dictyostelium discoideum OX=44689 GN=shkC PE=3 SV=1 Length=506 Score = 108 bits (271), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 82/277 (30%), Positives = 133/277 (48%), Gaps = 31/277 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FGKV + VAVK L K + S +++E+ ++ +YH +I Sbjct 30 IGTGSFGKVY------KGRCRQKAVAVKLLHKQNFDAATLSAFRKEVHLMSKIYHPNICL 83 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLF--AQQICEGMAYLHAQH- 1018 + G C G +V E VP G+L L I L L A+ G+ +LH + Sbjct 84 FMGACTIPGR--CVIVTELVPKGNLETLLHDQKIQLPLYLRMRMARDAALGINWLHESNP 141 Query 1019 -YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 ++HRD+ + N+L+D + VKI DFGL+ A+ + H+ + + + APE + + Sbjct 142 VFVHRDIKSSNLLVDENMRVKICDFGLS-ALKQKHKMLKDQSSAKGTPLYMAPEVMMFKE 200 Query 1078 FYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 F +SDV+SFG+ L+E+LT + S KF E + + + ER P Sbjct 201 FNESSDVYSFGIVLWEILTRKEPFSHHRELEKFREAVCV---------------KHERPP 245 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P+ C + L++ CW+ E RP+F+ +I L V Sbjct 246 IPNDCLDSLRRLIEKCWDKEPISRPSFKEIISALDHV 282 Score = 68.6 bits (166), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 65/252 (26%), Positives = 112/252 (44%), Gaps = 28/252 (11%) Query 631 RDRGQELRVVLKVLDPSHHDIAL--AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 + R ++ V +K+L + D A AF + LMS++ H ++ G C ++VTE Sbjct 40 KGRCRQKAVAVKLLHKQNFDAATLSAFRKEVHLMSKIYHPNICLFMGACTIPGRCVIVTE 99 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLG 746 V G L+ L ++ +P+ +M +A+ A +++L N VH ++ N+L+ Sbjct 100 LVPKGNLETLLHDQKIQLPLYLRMRMARDAALGINWLHESNPVFVHRDIKSSNLLVDE-- 157 Query 747 LAEGTSPFIKLSDPGVGLGALSREERVERIP--------WLAPECLPGGANSLSTAMDKW 798 + +K+ D GL AL ++ ++ + ++APE + + + D + Sbjct 158 -----NMRVKICD--FGLSALKQKHKMLKDQSSAKGTPLYMAPEVM--MFKEFNESSDVY 208 Query 799 GFGATLLEICFDGEAPLQSRSPSEK--EHFYQRQHRLPEPS--CPQLATLTSQCLTYEPT 854 FG L EI E P EK E + R P P+ L L +C EP Sbjct 209 SFGIVLWEILTRKE-PFSHHRELEKFREAVCVKHERPPIPNDCLDSLRRLIEKCWDKEPI 267 Query 855 QRPSFRTILRDL 866 RPSF+ I+ L Sbjct 268 SRPSFKEIISAL 279 >sp|P52583|VGFR2_COTJA Vascular endothelial growth factor receptor 2 OS=Coturnix japonica OX=93934 GN=KDR PE=1 SV=1 Length=1348 Score = 111 bits (277), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 62/177 (35%), Positives = 96/177 (54%), Gaps = 14/177 (8%) Query 990 LPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 L ++ + + L+ ++ Q+ GM +L ++ IHRDLAARN+LL ++ +VKI DFGLA+ + Sbjct 988 LCKNPLTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLSDNNVVKICDFGLARDIY 1047 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 + +Y R + D P+ W APE + + + SDVWSFGV L+E+ + +S P K Sbjct 1048 KDPDYVR-KGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFS-LGASPYPGVKID 1105 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 E L+ G R+ PD E+Y M +CW + RPTF L+ Sbjct 1106 E------------EFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGDPKQRPTFSELV 1150 Score = 53.1 bits (126), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 43/171 (25%), Positives = 76/171 (44%), Gaps = 26/171 (15%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V + Sbjct 1004 QVARGMEFLASRKCIHRDLAARNILLS-------DNNVVKICDFGLARDIYKDPDYVRKG 1056 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--EHFYQ 828 + W+APE + ++ + D W FG L EI G +P P K E F + Sbjct 1057 DARLPLKWMAPETIFDRVYTIQS--DVWSFGVLLWEIFSLGASPY----PGVKIDEEFCR 1110 Query 829 R-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 R + R P+ + P++ C +P QRP+F ++ L L N+ Sbjct 1111 RLKEGTRMRAPDYTTPEMYQTMLDCWHGDPKQRPTFSELVEHLGNLLQANV 1161 >sp|P41892|CDC7_SCHPO Cell division control protein 7 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=cdc7 PE=1 SV=1 Length=1062 Score = 110 bits (276), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 73/195 (37%), Positives = 102/195 (52%), Gaps = 13/195 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG+G FG V Y N GE VAVK +K + S K EID+L+ L H +I+K Sbjct 15 LGKGAFGAV----YRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVK 70 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYI 1020 Y+G Q SL +++EY GSLR I + L+ Q+ +G+ YLH Q I Sbjct 71 YRGSY--QTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLLYLHNQGVI 128 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ N+L D +K+ DFG+A + ++ V SP +W APE ++ Sbjct 129 HRDIKGANILTTKDGTIKLADFGVATKINALEDHSVV----GSP-YWMAPEVIELVGATT 183 Query 1081 ASDVWSFGVTLYELL 1095 ASD+WS G T+ ELL Sbjct 184 ASDIWSVGCTVIELL 198 Score = 65.5 bits (158), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 58/209 (28%), Positives = 91/209 (44%), Gaps = 17/209 (8%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 L+ + H ++ G ++ EY E+G L + + G +P + Q+ Sbjct 59 LLKNLDHPNIVKYRGSYQTNDSLCIILEYCENGSLRS-ICKNFGKIPENLVALYTFQVLQ 117 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIPW 778 L YL N+ ++H ++ G NIL + +GT IKL+D GV + AL V W Sbjct 118 GLLYLHNQGVIHRDIKGANILTTK----DGT---IKLADFGVATKINALEDHSVVGSPYW 170 Query 779 LAPECLP-GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS 837 +APE + GA +TA D W G T++E+ DG P P+ + P PS Sbjct 171 MAPEVIELVGA---TTASDIWSVGCTVIEL-LDGNPPYYDLDPTSALFRMVKDEHPPLPS 226 Query 838 CPQLA--TLTSQCLTYEPTQRPSFRTILR 864 A + QC +P R R +L+ Sbjct 227 NISSAAKSFLMQCFQKDPNLRIKTRKLLK 255 >sp|Q9ASQ5|CRCK3_ARATH Calmodulin-binding receptor-like cytoplasmic kinase 3 OS=Arabidopsis thaliana OX=3702 GN=CRCK3 PE=2 SV=1 Length=510 Score = 108 bits (270), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 66/200 (33%), Positives = 103/200 (52%), Gaps = 13/200 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG V D G++VA+K K + R+ +K E+D+L + H +++K Sbjct 231 IGEGGFGVVFKGVLD-----DGQVVAIKRAKKEHFENLRTEFKSEVDLLSKIGHRNLVKL 285 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHA--- 1016 G D+G++ L ++ EYV G+LRD+L + Q L +C G+ YLH+ Sbjct 286 LGYV-DKGDERL-IITEYVRNGTLRDHLDGARGTKLNFNQRLEIVIDVCHGLTYLHSYAE 343 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + IHRD+ + N+LL + K+ DFG A+ P + V + PE +K Y Sbjct 344 RQIIHRDIKSSNILLTDSMRAKVADFGFARGGPTDSNQTHILTQVKGTVGYLDPEYMKTY 403 Query 1077 KFYYASDVWSFGVTLYELLT 1096 SDV+SFG+ L E+LT Sbjct 404 HLTAKSDVYSFGILLVEILT 423 Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 51/205 (25%), Positives = 90/205 (44%), Gaps = 25/205 (12%) Query 632 DRGQELRVVLKVLDPSH-HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 D GQ V +K H ++ F L+S++ H +L + G +G E +++TEYV Sbjct 245 DDGQV--VAIKRAKKEHFENLRTEFKSEVDLLSKIGHRNLVKLLGYVDKGDERLIITEYV 302 Query 691 EHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLG 746 +G L L RG + ++ + + L+YL + + ++H ++ NILL Sbjct 303 RNGTLRDHLDGARGTKLNFNQRLEIVIDVCHGLTYLHSYAERQIIHRDIKSSNILLT--- 359 Query 747 LAEGTSPFIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWG 799 S K++D G G + + + +L PE + L+ D + Sbjct 360 ----DSMRAKVADFGFARGGPTDSNQTHILTQVKGTVGYLDPEYMK--TYHLTAKSDVYS 413 Query 800 FGATLLEICFDGEAPLQS-RSPSEK 823 FG L+EI G P+++ R P E+ Sbjct 414 FGILLVEI-LTGRRPVEAKRLPDER 437 >sp|Q40541|NPK1_TOBAC Mitogen-activated protein kinase kinase kinase NPK1 OS=Nicotiana tabacum OX=4097 GN=NPK1 PE=1 SV=1 Length=690 Score = 109 bits (273), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 75/283 (27%), Positives = 134/283 (47%), Gaps = 30/283 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-------DCGPQHRSGWKQEIDILRTLY 955 +G G FG+V Y N +GE++A+K + + H ++E+++L+ L Sbjct 86 IGCGAFGRV----YMGMNVDSGELLAIKEVSIAMNGASRERAQAHVRELEEEVNLLKNLS 141 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYL 1014 H +I++Y G + G SL +++E+VP GS+ L + S + + ++ +Q+ G+ YL Sbjct 142 HPNIVRYLGTAREAG--SLNILLEFVPGGSISSLLGKFGSFPESVIRMYTKQLLLGLEYL 199 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H +HRD+ N+L+DN +K+ DFG +K V E + +P +W APE + Sbjct 200 HKNGIMHRDIKGANILVDNKGCIKLADFGASKKVVELATMTGAKSMKGTP-YWMAPEVIL 258 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + +++D+WS G T+ E+ T PP +Q V L + Sbjct 259 QTGHSFSADIWSVGCTIIEMATG-----KPP--------WSQQYQEVAALFHIGTTKSHP 305 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEK 1175 P P+ E + C + E R + NL+ P + H++ Sbjct 306 PIPEHLSAESKDFLLKCLQKEPHLRHSASNLLQHPFVTAEHQE 348 Score = 50.8 bits (120), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 54/218 (25%), Positives = 93/218 (43%), Gaps = 21/218 (10%) Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 E +L+ +SH ++ G ++ E+V G + L + G P + + + Sbjct 132 EEVNLLKNLSHPNIVRYLGTAREAGSLNILLEFVPGGSISSLLGK-FGSFPESVIRMYTK 190 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-----VGLGALSREE 771 QL L YL ++H ++ G NIL+ G IKL+D G V L ++ + Sbjct 191 QLLLGLEYLHKNGIMHRDIKGANILVDNKGC-------IKLADFGASKKVVELATMTGAK 243 Query 772 RVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--- 827 ++ P W+APE + +S S D W G T++E+ G+ P + F+ Sbjct 244 SMKGTPYWMAPEVILQTGHSFSA--DIWSVGCTIIEMA-TGKPPWSQQYQEVAALFHIGT 300 Query 828 QRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + H +PE + +CL EP R S +L+ Sbjct 301 TKSHPPIPEHLSAESKDFLLKCLQKEPHLRHSASNLLQ 338 >sp|P28829|BYR2_SCHPO Protein kinase byr2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=byr2 PE=1 SV=1 Length=659 Score = 109 bits (273), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 68/218 (31%), Positives = 108/218 (50%), Gaps = 23/218 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-------GWKQEIDILRTLY 955 +G G FG+V Y N +GE++AVK + D + + EI +L+ L Sbjct 400 IGSGSFGQV----YLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELS 455 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYL 1014 HEHI++Y G + L + +EYVP GS+ L + S + F +Q +G+ YL Sbjct 456 HEHIVQYLGS--NLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYL 513 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV---REDGDSPVFWYAPE 1071 H++ +HRD+ N+L+DN +KI DFG++K + + R FW APE Sbjct 514 HSRGIVHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPE 573 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT------HCDSSQS 1103 +K+ +D+WS G + E+LT +CD Q+ Sbjct 574 VVKQTMHTEKTDIWSLGCLVIEMLTSKHPYPNCDQMQA 611 Score = 40.8 bits (94), Expect = 0.088, Method: Compositional matrix adjust. Identities = 42/170 (25%), Positives = 69/170 (41%), Gaps = 20/170 (12%) Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 H + A +L+ ++SH H+ G + + EYV G + L Sbjct 437 HAKLLDALAGEIALLQELSHEHIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEE 496 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---- 763 K + Q L L YL ++ +VH ++ G NIL+ G IK+SD G+ Sbjct 497 TLVKNFIKQTLK-GLEYLHSRGIVHRDIKGANILVDNKGK-------IKISDFGISKKLE 548 Query 764 LGALSREERVERIP------WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 L + S + R W+APE + ++ T D W G ++E+ Sbjct 549 LNSTSTKTGGARPSFQGSSFWMAPEVVKQTMHTEKT--DIWSLGCLVIEM 596 >sp|P79750|CSF11_TAKRU Macrophage colony-stimulating factor 1 receptor 1 OS=Takifugu rubripes OX=31033 GN=csf1r1 PE=3 SV=1 Length=975 Score = 110 bits (274), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 60/169 (36%), Positives = 99/169 (59%), Gaps = 16/169 (9%) Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + + LL F+ Q+ +G+ +L +++ IHRD+AARNVLL + R+ KI DFGLA+ + Y Sbjct 754 LDIDDLLRFSLQVAQGLDFLASRNCIHRDVAARNVLLTDKRVAKICDFGLARDIMNDSNY 813 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIG 1113 V+ + PV W APE + + + SDVWS+G+ L+E+ + +SP P+ ++ Sbjct 814 V-VKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFS---LGKSPYPSMAVD--- 866 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 R ++++RG ++ +PD E+Y +MK CW E + RPTF Sbjct 867 --------SRFYKMVKRGYQMSQPDFALPEIYMIMKMCWNLEPTERPTF 907 Score = 65.9 bits (159), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 44/164 (27%), Positives = 81/164 (49%), Gaps = 22/164 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A L +L ++N +H +V RN+LL +A K+ D G+ ++ V + Sbjct 765 QVAQGLDFLASRNCIHRDVAARNVLLTDKRVA-------KICDFGLARDIMNDSNYVVKG 817 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-- 828 + W+APE + ++ + D W +G L EI G++P S + + FY+ Sbjct 818 NARLPVKWMAPESIFDCVYTVQS--DVWSYGILLWEIFSLGKSPYPSMAVDSR--FYKMV 873 Query 829 -RQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 R +++ +P + P++ + C EPT+RP+F I + + RL Sbjct 874 KRGYQMSQPDFALPEIYMIMKMCWNLEPTERPTFSMISQMINRL 917 Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 47/168 (28%), Positives = 76/168 (45%), Gaps = 17/168 (10%) Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS-PASDPTVFHKRYLKKIRDLGEGHFG 909 Y+ Q+P F + + + +N ++P P ++ F + LK + LG G FG Sbjct 540 YKYKQKPRFEIRWKIIEAREGNNYT---FIDPTQLPYNEKWEFPRDKLKLGKVLGAGAFG 596 Query 910 KVSLYCYDPTNDGTGE------MVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKY 962 KV + T G GE VAVK LKA+ R E+ IL L +H++I+ Sbjct 597 KV----VEATAFGLGEDKDNTLRVAVKMLKANAHSDEREALMSELKILSHLGHHQNIVNL 652 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEG 1010 G C G + ++ EY LG L ++L + + L++ +I E Sbjct 653 LGACTYGG--PVLVITEYCSLGDLLNFLRQKAETFVNLVMNIPEIMEN 698 Score = 35.8 bits (81), Expect = 3.6, Method: Compositional matrix adjust. Identities = 24/86 (28%), Positives = 42/86 (49%), Gaps = 2/86 (2%) Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSH-THLAFVHGV 676 GK+ + G D+ LRV +K+L +H D A ++S + H ++ + G Sbjct 596 GKVVEATAFGLGEDKDNTLRVAVKMLKANAHSDEREALMSELKILSHLGHHQNIVNLLGA 655 Query 677 CVRGPENIMVTEYVEHGPLDVWLRRE 702 C G +++TEY G L +LR++ Sbjct 656 CTYGGPVLVITEYCSLGDLLNFLRQK 681 >sp|Q9PUF6|PGFRA_CHICK Platelet-derived growth factor receptor alpha OS=Gallus gallus OX=9031 GN=PDGFRA PE=2 SV=1 Length=1087 Score = 109 bits (273), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 63/179 (35%), Positives = 94/179 (53%), Gaps = 16/179 (9%) Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + L LL F Q+ GM +L +++ +HRDLAARNVLL ++VKI DFGLA+ + Y Sbjct 790 LSLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNY 849 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + PV W APE + + + SDVWS+G+ L+E+ + L GI Sbjct 850 VS-KGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFS--------------LGGI 894 Query 1115 AQ-GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 G M ++ G R+ +PD EVY +M CW E RP+F +L I++++ Sbjct 895 LYPGMMVDSTFYNKIKSGYRMAKPDHATNEVYEIMVKCWNNEPEKRPSFYHLSEIVESL 953 Score = 52.0 bits (123), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 40/154 (26%), Positives = 68/154 (44%), Gaps = 22/154 (14%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L +KN VH ++ RN+LLA+ +K+ D G+ + V + Sbjct 801 QVARGMEFLASKNCVHRDLAARNVLLAQ-------GKIVKICDFGLARDIMHDSNYVSKG 853 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + N +T D W +G L EI G FY + Sbjct 854 STFLPVKWMAPESI--FDNLYTTLSDVWSYGILLWEIFSLGGILYPGMMVDST--FYNKI 909 Query 830 --QHRLPEP--SCPQLATLTSQCLTYEPTQRPSF 859 +R+ +P + ++ + +C EP +RPSF Sbjct 910 KSGYRMAKPDHATNEVYEIMVKCWNNEPEKRPSF 943 >sp|P35918|VGFR2_MOUSE Vascular endothelial growth factor receptor 2 OS=Mus musculus OX=10090 GN=Kdr PE=1 SV=2 Length=1345 Score = 109 bits (272), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 70/197 (36%), Positives = 103/197 (52%), Gaps = 20/197 (10%) Query 971 EKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029 EKSL V E L +D+L L L+ ++ Q+ +GM +L ++ IHRDLAARN+ Sbjct 978 EKSLSDVEEEEASEELYKDFLT-----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNI 1032 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 LL +VKI DFGLA+ + + +Y R + D P+ W APE + + + SDVWSFGV Sbjct 1033 LLSEKNVVKICDFGLARDIYKDPDYVR-KGDARLPLKWMAPETIFDRVYTIQSDVWSFGV 1091 Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149 L+E+ + +S P K E L+ G R+ PD E+Y M Sbjct 1092 LLWEIFS-LGASPYPGVKIDE------------EFCRRLKEGTRMRAPDYTTPEMYQTML 1138 Query 1150 NCWETEASFRPTFENLI 1166 +CW + + RP+F L+ Sbjct 1139 DCWHEDPNQRPSFSELV 1155 Score = 57.4 bits (137), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 50/199 (25%), Positives = 86/199 (43%), Gaps = 38/199 (19%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V + Sbjct 1009 QVAKGMEFLASRKCIHRDLAARNILLSEKNV-------VKICDFGLARDIYKDPDYVRKG 1061 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--EHFYQ 828 + W+APE + ++ + D W FG L EI G +P P K E F + Sbjct 1062 DARLPLKWMAPETIFDRVYTIQS--DVWSFGVLLWEIFSLGASPY----PGVKIDEEFCR 1115 Query 829 R-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN---------- 873 R + R P+ + P++ C +P QRPSF ++ L L N Sbjct 1116 RLKEGTRMRAPDYTTPEMYQTMLDCWHEDPNQRPSFSELVEHLGNLLQANAQQDGKDYIV 1175 Query 874 --LADVLTVNPDSPASDPT 890 +++ L++ DS S PT Sbjct 1176 LPMSETLSMEEDSGLSLPT 1194 >sp|Q8VDG6|M3K21_MOUSE Mitogen-activated protein kinase kinase kinase 21 OS=Mus musculus OX=10090 GN=Map3k21 PE=1 SV=2 Length=1002 Score = 108 bits (271), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 99/319 (31%), Positives = 148/319 (46%), Gaps = 60/319 (19%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW-----KQ 946 F + LK++ +G G FG+V + G+ VAVKA + D P+ + ++ Sbjct 107 FERLELKEL--IGAGGFGQVYRATWQ------GQEVAVKAARRD--PEQDAAAAAESVRR 156 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------------ 994 E + L H +II+ +G C Q L LV+E+ G+L L + Sbjct 157 EARLFAMLRHPNIIQLRGVCLRQ--PHLCLVLEFARGGALNRALAAAASDPRAPGPRRAR 214 Query 995 -IGLAQLLLFAQQICEGMAYLHAQHYI---HRDLAARNVLL------DN--DRLVKIGDF 1042 I L+ +A QI GM YLH + + HRDL + N+LL D+ ++ +KI DF Sbjct 215 RIPPQVLVNWAVQIARGMLYLHEEAVVPILHRDLKSSNILLLEKIEHDDICNKTLKITDF 274 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 GLA+ E H R+ G W APE ++ F SD+WS+GV L+ELLT Sbjct 275 GLAR---EWHRTTRMSAAGT--YAWMAPEVIRSSLFSKGSDIWSYGVLLWELLTG----- 324 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 P + ++ + +A G + V +LT LP P CP LMK CWE + RP+F Sbjct 325 EVPYRGIDGLAVAYG-VAVNKLT--------LPIPSTCPEPFAKLMKECWEQDPHIRPSF 375 Query 1163 ENLIPILKTVHEKYQGQAP 1181 ++ L + E P Sbjct 376 ALILQQLTAIEEAVLTNMP 394 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 73/272 (27%), Positives = 118/272 (43%), Gaps = 35/272 (13%) Query 633 RGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 +GQE+ V DP A A A L + + H ++ + GVC+R P +V E+ Sbjct 130 QGQEVAVKAARRDPEQDAAAAAESVRREARLFAMLRHPNIIQLRGVCLRQPHLCLVLEFA 189 Query 691 EHGPLDVWLRRERGH-----------VPMAWKMVVAQQLASALSYLENKNLV---HGNVC 736 G L+ L +P + A Q+A + YL + +V H ++ Sbjct 190 RGGALNRALAAAASDPRAPGPRRARRIPPQVLVNWAVQIARGMLYLHEEAVVPILHRDLK 249 Query 737 GRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSRE-ERVERI------PWLAPECLPGGA 788 NILL ++ + + +K++D G L+RE R R+ W+APE + + Sbjct 250 SSNILLLEKIEHDDICNKTLKITDFG-----LAREWHRTTRMSAAGTYAWMAPEVI--RS 302 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPS-CPQ-LATLT 845 + S D W +G L E+ GE P + + + LP PS CP+ A L Sbjct 303 SLFSKGSDIWSYGVLLWEL-LTGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLM 361 Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 +C +P RPSF IL+ LT ++ L ++ Sbjct 362 KECWEQDPHIRPSFALILQQLTAIEEAVLTNM 393 >sp|P79701|VGFR3_COTCO Vascular endothelial growth factor receptor 3 OS=Coturnix coturnix OX=9091 GN=FLT4 PE=2 SV=1 Length=1379 Score = 109 bits (272), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 61/182 (34%), Positives = 98/182 (54%), Gaps = 14/182 (8%) Query 988 DYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 D L + + + L+ ++ Q+ GM +L ++ IHRDLAARN+LL + +VKI DFGLA+ Sbjct 1014 DDLWQSPLTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLSENNVVKICDFGLARD 1073 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + + +Y R + P+ W APE + + + SDVWSFGV L+E+ + +S P + Sbjct 1074 IYKDPDYVR-KGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFS-LGASPYPGVQ 1131 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 E + + G R+ P+ E+Y +M +CW + RPTF +L+ Sbjct 1132 INE------------EFCQRFKDGTRMRAPEYTTAEIYRIMLSCWHGDPKERPTFSDLVE 1179 Query 1168 IL 1169 IL Sbjct 1180 IL 1181 Score = 54.7 bits (130), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 48/193 (25%), Positives = 86/193 (45%), Gaps = 27/193 (14%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V + Sbjct 1032 QVARGMEFLASRKCIHRDLAARNILLSENNV-------VKICDFGLARDIYKDPDYVRKG 1084 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + +T D W FG L EI G +P +E+ F QR Sbjct 1085 SARLPLKWMAPESIFDKV--YTTQSDVWSFGVLLWEIFSLGASPYPGVQINEE--FCQRF 1140 Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL----ADVLTVN 881 + R PE + ++ + C +P +RP+F ++ L L N+ D + +N Sbjct 1141 KDGTRMRAPEYTTAEIYRIMLSCWHGDPKERPTFSDLVEILGNLLQENVQQEGKDYIPLN 1200 Query 882 PDSPASDPTVFHK 894 DS +S+ F + Sbjct 1201 -DSHSSEDDGFSQ 1212 >sp|P20786|PGFRA_RAT Platelet-derived growth factor receptor alpha OS=Rattus norvegicus OX=10116 GN=Pdgfra PE=1 SV=2 Length=1088 Score = 108 bits (271), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 65/181 (36%), Positives = 92/181 (51%), Gaps = 23/181 (13%) Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + L LL F Q+ GM +L +++ +HRDLAARNVLL ++VKI DFGLA+ + Y Sbjct 789 LTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNY 848 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + PV W APE + + + SDVWS+GV L+E+ + L G Sbjct 849 VS-KGSTFLPVKWMAPESIFDNLYTTLSDVWSYGVLLWEIFS--------------LGGT 893 Query 1115 AQ-GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF-------ENLI 1166 G M ++ G R+ +PD EVY +M CW +E RP+F ENL+ Sbjct 894 PYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLL 953 Query 1167 P 1167 P Sbjct 954 P 954 Score = 58.2 bits (139), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 44/166 (27%), Positives = 73/166 (44%), Gaps = 22/166 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L +KN VH ++ RN+LLA+ +K+ D G+ + V + Sbjct 800 QVARGMEFLASKNCVHRDLAARNVLLAQ-------GKIVKICDFGLARDIMHDSNYVSKG 852 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + N +T D W +G L EI G P FY + Sbjct 853 STFLPVKWMAPESI--FDNLYTTLSDVWSYGVLLWEIFSLGGTPYPGMMVDST--FYNKI 908 Query 830 --QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 +R+ +P + ++ + QC EP +RPSF + + L P Sbjct 909 KSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLP 954 >sp|Q9CAD5|YODA_ARATH Mitogen-activated protein kinase kinase kinase YODA OS=Arabidopsis thaliana OX=3702 GN=YDA PE=1 SV=1 Length=883 Score = 108 bits (270), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 93/293 (32%), Positives = 137/293 (47%), Gaps = 33/293 (11%) Query 882 PDSPA-SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQ 939 P SPA ++ TV KK R LG G FG V L N +GEM A+K + P+ Sbjct 384 PRSPARAEATVSPGSRWKKGRLLGMGSFGHVYLGF----NSESGEMCAMKEVTLCSDDPK 439 Query 940 HRSGWKQ---EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-I 995 R +Q EI +L L H++I++Y G + + L + +EYV GS+ L + Sbjct 440 SRESAQQLGQEISVLSRLRHQNIVQYYG--SETVDDKLYIYLEYVSGGSIYKLLQEYGQF 497 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 G + + QQI G+AYLHA++ +HRD+ N+L+D VK+ DFG+AK + Sbjct 498 GENAIRNYTQQILSGLAYLHAKNTVHRDIKGANILVDPHGRVKVADFGMAKHITAQSGPL 557 Query 1056 RVREDGDSPVFWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + SP +W APE +K A D+WS G T+ E+ T PP E Sbjct 558 SFK---GSP-YWMAPEVIKNSNGSNLAVDIWSLGCTVLEMAT-----TKPPWSQYE---- 604 Query 1115 AQGQMTVLRLTELLERGERLPR-PDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 G + ++ E LP PD E ++ C + + RPT L+ Sbjct 605 --GVPAMFKIGNSKE----LPDIPDHLSEEGKDFVRKCLQRNPANRPTAAQLL 651 Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 49/173 (28%), Positives = 80/173 (46%), Gaps = 12/173 (7%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V L DP + A + S++S++ H ++ +G + + EYV G + Sbjct 431 VTLCSDDPKSRESAQQLGQEISVLSRLRHQNIVQYYGSETVDDKLYIYLEYVSGGSI-YK 489 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 L +E G QQ+ S L+YL KN VH ++ G NIL+ G +K++ Sbjct 490 LLQEYGQFGENAIRNYTQQILSGLAYLHAKNTVHRDIKGANILVDPHGR-------VKVA 542 Query 759 DPGVG--LGALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 D G+ + A S + P W+APE + +N + A+D W G T+LE+ Sbjct 543 DFGMAKHITAQSGPLSFKGSPYWMAPEVI-KNSNGSNLAVDIWSLGCTVLEMA 594 >sp|P26618|PGFRA_MOUSE Platelet-derived growth factor receptor alpha OS=Mus musculus OX=10090 GN=Pdgfra PE=1 SV=3 Length=1089 Score = 108 bits (270), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 63/180 (35%), Positives = 92/180 (51%), Gaps = 21/180 (12%) Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + L LL F Q+ GM +L +++ +HRDLAARNVLL ++VKI DFGLA+ + Y Sbjct 790 LTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNY 849 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + PV W APE + + + SDVWS+G+ L+E+ + + P Sbjct 850 VS-KGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFS-LGGTPYP---------- 897 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF-------ENLIP 1167 G M ++ G R+ +PD EVY +M CW +E RP+F ENL+P Sbjct 898 --GMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLP 955 Score = 57.8 bits (138), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 44/166 (27%), Positives = 73/166 (44%), Gaps = 22/166 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L +KN VH ++ RN+LLA+ +K+ D G+ + V + Sbjct 801 QVARGMEFLASKNCVHRDLAARNVLLAQ-------GKIVKICDFGLARDIMHDSNYVSKG 853 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + N +T D W +G L EI G P FY + Sbjct 854 STFLPVKWMAPESI--FDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDST--FYNKI 909 Query 830 --QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 +R+ +P + ++ + QC EP +RPSF + + L P Sbjct 910 KSGYRMAKPDHATSEVYEIMVQCWNSEPEKRPSFYHLSEIVENLLP 955 >sp|P16234|PGFRA_HUMAN Platelet-derived growth factor receptor alpha OS=Homo sapiens OX=9606 GN=PDGFRA PE=1 SV=1 Length=1089 Score = 108 bits (269), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 63/180 (35%), Positives = 92/180 (51%), Gaps = 21/180 (12%) Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + L LL F Q+ GM +L +++ +HRDLAARNVLL ++VKI DFGLA+ + Y Sbjct 790 LTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNY 849 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + PV W APE + + + SDVWS+G+ L+E+ + + P Sbjct 850 VS-KGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFS-LGGTPYP---------- 897 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF-------ENLIP 1167 G M ++ G R+ +PD EVY +M CW +E RP+F ENL+P Sbjct 898 --GMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLP 955 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 43/166 (26%), Positives = 73/166 (44%), Gaps = 22/166 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L +KN VH ++ RN+LLA+ +K+ D G+ + V + Sbjct 801 QVARGMEFLASKNCVHRDLAARNVLLAQ-------GKIVKICDFGLARDIMHDSNYVSKG 853 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + N +T D W +G L EI G P FY + Sbjct 854 STFLPVKWMAPESI--FDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDST--FYNKI 909 Query 830 --QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 +R+ +P + ++ + +C EP +RPSF + + L P Sbjct 910 KSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLP 955 >sp|Q39008|M3K1_ARATH Mitogen-activated protein kinase kinase kinase 1 OS=Arabidopsis thaliana OX=3702 GN=MEKK1 PE=1 SV=2 Length=608 Score = 107 bits (266), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 83/272 (31%), Positives = 131/272 (48%), Gaps = 36/272 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQ---EIDILRTLYHEH 958 LG G FG V Y+ + G G+ AVK + D G Q + +Q EI +L L H++ Sbjct 339 LGRGSFGSV----YEGIS-GDGDFFAVKEVSLLDQGSQAQECIQQLEGEIKLLSQLQHQN 393 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I++Y+G +D +L + +E V GSL R+ + + + L+ +QI +G+ YLH + Sbjct 394 IVRYRGTAKDG--SNLYIFLELVTQGSLLKLYQRYQLRDSVVSLYTRQILDGLKYLHDKG 451 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL--KEY 1076 +IHRD+ N+L+D + VK+ DFGLAK ++ ++ +P FW APE + K+ Sbjct 452 FIHRDIKCANILVDANGAVKLADFGLAKV----SKFNDIKSCKGTP-FWMAPEVINRKDS 506 Query 1077 KFYYA-SDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 Y + +D+WS G T+ E+ T S P + L IG RG Sbjct 507 DGYGSPADIWSLGCTVLEMCTGQIPYSDLEPVQALFRIG----------------RGTLP 550 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 PD + + C + RPT L+ Sbjct 551 EVPDTLSLDARLFILKCLKVNPEERPTAAELL 582 Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 67/279 (24%), Positives = 114/279 (41%), Gaps = 45/279 (16%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LG+G+ +VYEG + G GD K V D+G + + ++ L+ Sbjct 339 LGRGSFGSVYEG---ISGDGDFFAVKE------VSLLDQGSQAQECIQQLEGE------- 382 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 L+SQ+ H ++ G G + E V G L +R + + + Sbjct 383 ----IKLLSQLQHQNIVRYRGTAKDGSNLYIFLELVTQGSL--LKLYQRYQLRDSVVSLY 436 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 +Q+ L YL +K +H ++ NIL+ G +KL+D GL +S+ ++ Sbjct 437 TRQILDGLKYLHDKGFIHRDIKCANILVDANGA-------VKLAD--FGLAKVSKFNDIK 487 Query 775 RIP----WLAPECLP-GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 W+APE + ++ + D W G T+LE+C G+ P P + R Sbjct 488 SCKGTPFWMAPEVINRKDSDGYGSPADIWSLGCTVLEMC-TGQIPYSDLEPVQALF---R 543 Query 830 QHRLPEPSCPQLATLTS-----QCLTYEPTQRPSFRTIL 863 R P P +L + +CL P +RP+ +L Sbjct 544 IGRGTLPEVPDTLSLDARLFILKCLKVNPEERPTAAELL 582 >sp|H2L099|GCK1_CAEEL Germinal center kinase 1 OS=Caenorhabditis elegans OX=6239 GN=gck-1 PE=1 SV=1 Length=653 Score = 107 bits (266), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 70/207 (34%), Positives = 112/207 (54%), Gaps = 13/207 (6%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP V + K+ R +G G FG+V Y ++ TG +VA+K + + +QE Sbjct 29 DPEVI---FTKQER-IGRGSFGEV----YKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQE 80 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +L +++ KY G +G K L ++MEY+ GS D + + + + ++I Sbjct 81 IQVLSQCDSQYVTKYFGSFL-KGSK-LWIIMEYLGGGSALDLTKSGKLDESHIAVILREI 138 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 +G+ YLH++ IHRD+ A NVL+ VK+ DFG+A + E + R+ G SP FW Sbjct 139 LKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVK-KRITFVG-SP-FW 195 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYEL 1094 APE +K+ + Y +D+WS G+T EL Sbjct 196 MAPELIKQSSYDYKADIWSLGITAIEL 222 Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust. Identities = 57/241 (24%), Positives = 102/241 (42%), Gaps = 34/241 (14%) Query 639 VVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LD 696 V +K++D D + ++SQ ++ G ++G + ++ EY+ G LD Sbjct 60 VAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALD 119 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 + + G + + V+ +++ L YL ++ +H ++ N+L++ G +K Sbjct 120 L---TKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHG-------DVK 169 Query 757 LSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 ++D GV G L+ E +RI W+APE + +S D W G T +E+ + Sbjct 170 VADFGVA-GQLT-ETVKKRITFVGSPFWMAPELIK--QSSYDYKADIWSLGITAIELA-N 224 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-------SCPQLATLTSQCLTYEPTQRPSFRTIL 863 GE P P + P P S P CL +P RPS T+L Sbjct 225 GEPPHSDLHPMRVLFLIPKN---PPPVLQGSQWSKP-FKEFVEMCLNKDPENRPSASTLL 280 Query 864 R 864 + Sbjct 281 K 281 >sp|E9Q3S4|M3K19_MOUSE Mitogen-activated protein kinase kinase kinase 19 OS=Mus musculus OX=10090 GN=Map3k19 PE=3 SV=1 Length=1311 Score = 108 bits (269), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 72/234 (31%), Positives = 121/234 (52%), Gaps = 22/234 (9%) Query 876 DVLTVNPDSPASDPTVFHKR--YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933 + LT N SD ++ H+ + K LG G +G V YC + G+++AVK + Sbjct 1021 NFLTSNEKKTLSDKSLNHEEAIFWTKGEILGRGAYGTV--YCGLTS---LGQLIAVKQVA 1075 Query 934 ADCG-----PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 D + ++E+D+L+ L H +I+ Y G C + E +L + ME+VP GS+ Sbjct 1076 LDTSDKLATEKEYRKLQEEVDLLKALKHVNIVAYLGTCLE--ENTLSIFMEFVPGGSISS 1133 Query 989 YLPRHSIGLAQLLL--FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 + R L +++ + +QI +G+AYLH +HRD+ NV+L ++K+ DFG AK Sbjct 1134 IINRFG-PLPEMVFCKYTRQILQGVAYLHDNCVVHRDIKGNNVMLMPTGIIKLIDFGCAK 1192 Query 1047 AVP----EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 + G ++ +P +W APE + E + SD+WS G T++E+ T Sbjct 1193 RLAWAGLNGTHSDMLKSMRGTP-YWMAPEVINESGYGRKSDIWSIGCTVFEMAT 1245 Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 55/225 (24%), Positives = 89/225 (40%), Gaps = 27/225 (12%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 E L+ + H ++ G C+ + E+V G + + R G +P Sbjct 1091 LQEEVDLLKALKHVNIVAYLGTCLEENTLSIFMEFVPGGSISSIINR-FGPLPEMVFCKY 1149 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-------VGLGAL 767 +Q+ ++YL + +VH ++ G N++L G+ IKL D G GL Sbjct 1150 TRQILQGVAYLHDNCVVHRDIKGNNVMLMPTGI-------IKLIDFGCAKRLAWAGLNGT 1202 Query 768 SRE--ERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + + + P W+APE + + D W G T+ E+ G+ PL S Sbjct 1203 HSDMLKSMRGTPYWMAPEVI--NESGYGRKSDIWSIGCTVFEMAT-GKPPLASMD-RMAA 1258 Query 825 HFYQRQHRLPEPSCPQ-----LATLTSQCLTYEPTQRPSFRTILR 864 FY HR P P A CLT + +RPS +L+ Sbjct 1259 MFYIGAHRGLMPPLPARFSEPAADFVRLCLTRDQHERPSALQLLK 1303 >sp|A0A0K3AV08|MLK1_CAEEL Mitogen-activated protein kinase kinase kinase mlk-1 OS=Caenorhabditis elegans OX=6239 GN=mlk-1 PE=1 SV=1 Length=1059 Score = 107 bits (268), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 81/275 (29%), Positives = 123/275 (45%), Gaps = 53/275 (19%) Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQL 1000 K+E +++ L H +I++ G C + + L++E SLR+ +I L L Sbjct 217 KREANLVNGLSHNNIVRLLGICLE--DPYFGLLLELCEGSSLRNVCRNLNSDAAIPLGVL 274 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN------------------------DRL 1036 + +A Q+ EGM YL Q Y+HRDL A NVL+ D+L Sbjct 275 IDWATQVAEGMEYLTKQGYVHRDLKADNVLVKEEVCLCMDEEMFQYAYCLKCGKRPFDKL 334 Query 1037 -VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 +KI DFG+ + + + W APE KE + ASDVWS+GV L+ELL Sbjct 335 QLKITDFGVTRKMTADANRFSTA----GTYAWLAPEAFKEGTWSEASDVWSYGVVLWELL 390 Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155 T + P QG + ++ +G+ L D CP LM++CW E Sbjct 391 TR----EEP----------YQGHIPATIAFQIANKGQNLSIGDSCPDRWKKLMQDCWNLE 436 Query 1156 ASFRPTFENLIPILKTVHEKYQG----QAPSVFSV 1186 +FRP F L K ++++ +APS +V Sbjct 437 PNFRPKFSTLAISFKQYAKEFKDTHLQRAPSKMAV 471 Score = 57.4 bits (137), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 70/305 (23%), Positives = 120/305 (39%), Gaps = 49/305 (16%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 +G G V++ ++++ + + G+M G G +++ LK + + Sbjct 155 QIGHGATATVFKMDIKIKK--ELQNGRM--------GEAVGDQMKAALKRFNRHASNFRA 204 Query 654 AFYET----------ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-- 701 T A+L++ +SH ++ + G+C+ P ++ E E L R Sbjct 205 DVVSTDEQLEQLKREANLVNGLSHNNIVRLLGICLEDPYFGLLLELCEGSSLRNVCRNLN 264 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR---LGLAE--------- 749 +P+ + A Q+A + YL + VH ++ N+L+ L + E Sbjct 265 SDAAIPLGVLIDWATQVAEGMEYLTKQGYVHRDLKADNVLVKEEVCLCMDEEMFQYAYCL 324 Query 750 --GTSPF----IKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGF 800 G PF +K++D GV + R WLAPE G + S A D W + Sbjct 325 KCGKRPFDKLQLKITDFGVTRKMTADANRFSTAGTYAWLAPEAFKEG--TWSEASDVWSY 382 Query 801 GATLLEICFDGEAPLQSRSPSEK--EHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQRP 857 G L E+ E P Q P+ + + Q+ SCP + L C EP RP Sbjct 383 GVVLWEL-LTREEPYQGHIPATIAFQIANKGQNLSIGDSCPDRWKKLMQDCWNLEPNFRP 441 Query 858 SFRTI 862 F T+ Sbjct 442 KFSTL 446 >sp|Q13546|RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 OS=Homo sapiens OX=9606 GN=RIPK1 PE=1 SV=3 Length=671 Score = 106 bits (265), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 88/275 (32%), Positives = 129/275 (47%), Gaps = 32/275 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +L G FGKVSL C+ T G M+ K +H +E ++ L H ++K Sbjct 22 ELDSGGFGKVSL-CFHRTQ---GLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVK 77 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G ++G+ SL VMEY+ G+L L S L+ +I EGM YLH + I Sbjct 78 LLGVIIEEGKYSL--VMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMCYLHGKGVI 135 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAK----AVPEGHEYYRVRE-DGDSP-----VFWYAP 1070 H+DL N+L+DND +KI D GLA + E+ +RE DG + +++ AP Sbjct 136 HKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMAP 195 Query 1071 ECLKEY--KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM-TVLRLTEL 1127 E L + K SDV+SF V L+ + + + ++ + ++ I G V +TE Sbjct 196 EHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEY 255 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 CP E+ LMK CWE RPTF Sbjct 256 ------------CPREIISLMKLCWEANPEARPTF 278 Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust. Identities = 52/232 (22%), Positives = 95/232 (41%), Gaps = 32/232 (14%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 A E A +M+++ H+ + + GV + + +V EY+E G L L+ E P++ K Sbjct 59 ALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMS-TPLSVKGR 117 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGALSR 769 + ++ + YL K ++H ++ NIL+ IK++D G+ L+ Sbjct 118 IILEIIEGMCYLHGKGVIHKDLKPENILV-------DNDFHIKIADLGLASFKMWSKLNN 170 Query 770 EERVE-------------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 EE E + ++APE L + D + F L I F + P + Sbjct 171 EEHNELREVDGTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAI-FANKEPYE 229 Query 817 SRSPSEKEHFYQRQHRLPEPS-----CP-QLATLTSQCLTYEPTQRPSFRTI 862 + ++ + P+ CP ++ +L C P RP+F I Sbjct 230 NAICEQQLIMCIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGI 281 >sp|O64842|PBL12_ARATH Probable serine/threonine-protein kinase PBL12 OS=Arabidopsis thaliana OX=3702 GN=PBL12 PE=2 SV=1 Length=424 Score = 104 bits (259), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 97/285 (34%), Positives = 136/285 (48%), Gaps = 21/285 (7%) Query 903 LGEGHFGKV-SLYCYDPTNDGT-GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LGEG FG V + D G + VAVKAL HR W EI L L ++H++ Sbjct 94 LGEGGFGPVYKGFIDDKVKPGIEAQPVAVKALDLHGHQGHRE-WLAEILFLGQLSNKHLV 152 Query 961 KYKG-CCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLA--QLLLFAQQICEGMAYLHA 1016 K G CCE E+ LV EY+P GSL + L R+S+ +A + A +G+A+LH Sbjct 153 KLIGFCCE---EEQRVLVYEYMPRGSLENQLFRRNSLAMAWGIRMKIALGAAKGLAFLHE 209 Query 1017 QH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG-HEYYRVREDGDSPVFWYAPECL 1073 I+RD N+LLD+D K+ DFGLAK PEG H + R G + APE + Sbjct 210 AEKPVIYRDFKTSNILLDSDYNAKLSDFGLAKDGPEGEHTHVTTRVMGTQG--YAAPEYI 267 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER--G 1131 +DV+SFGV L EL+T S + T+ + + + +LR LER Sbjct 268 MTGHLTTMNDVYSFGVVLLELITGKRSMDNTRTRREQ--SLVEWARPMLRDQRKLERIID 325 Query 1132 ERLPRPDKCPCE--VYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 RL K L C +RPT ++ +L+++ E Sbjct 326 PRLANQHKTEAAQVAASLAYKCLSQHPKYRPTMCEVVKVLESIQE 370 Score = 60.8 bits (146), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 81/329 (25%), Positives = 135/329 (41%), Gaps = 56/329 (17%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 + + L L LS RV ++ + LG+G VY+G + +D + P Sbjct 69 TSQKLRLFTLSELRVITHNFSRSNMLGEGGFGPVYKGFI---------------DDKVKP 113 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G + V +K LD H + + Q+S+ HL + G C + ++V EY Sbjct 114 GIEAQP---VAVKALDLHGHQGHREWLAEILFLGQLSNKHLVKLIGFCCEEEQRVLVYEY 170 Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARL 745 + G L+ L R R + MAW +M +A A L++L K +++ + NILL Sbjct 171 MPRGSLENQLFR-RNSLAMAWGIRMKIALGAAKGLAFLHEAEKPVIYRDFKTSNILL--- 226 Query 746 GLAEGTSPFIKLSDPGVGLGALSREER--VERI----PWLAPECLPGGANSLSTAMDKWG 799 + KLSD G+ E R+ + APE + G L+T D + Sbjct 227 ----DSDYNAKLSDFGLAKDGPEGEHTHVTTRVMGTQGYAAPEYIMTG--HLTTMNDVYS 280 Query 800 FGATLLEICFDGEAPLQSRSPSEKEH------FYQRQHRLPEPSCPQL------------ 841 FG LLE+ + +R+ E+ + Q +L P+L Sbjct 281 FGVVLLELITGKRSMDNTRTRREQSLVEWARPMLRDQRKLERIIDPRLANQHKTEAAQVA 340 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 A+L +CL+ P RP+ +++ L +Q Sbjct 341 ASLAYKCLSQHPKYRPTMCEVVKVLESIQ 369 >sp|Q9LTC0|PBL19_ARATH Probable serine/threonine-protein kinase PBL19 OS=Arabidopsis thaliana OX=3702 GN=PBL19 PE=1 SV=1 Length=410 Score = 104 bits (259), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 110/382 (29%), Positives = 172/382 (45%), Gaps = 38/382 (10%) Query 815 LQSRSPSEKEHFYQRQHR----LPEPSCPQLA--TLTSQCLTYEPTQRPSFRTILRDLTR 868 +S+ P +++ + R L + S P+L + TS P PS R+I +DL Sbjct 7 FKSKKPRKQQKDNNKNKRKGKELLQNSAPELTNRSETSSFNLQTPRSLPSPRSI-KDLYT 65 Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE--- 925 + NL V + S A+ VF ++ + +GEG FG V Y ++G Sbjct 66 EREQNLR-VFSYEELSKAT--YVFSRKLV-----IGEGGFGIV--YKGKILSNGDSSDPP 115 Query 926 -MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ--LVMEYVP 982 +VA+K L G Q W E+ L + H +++K G C + GE ++ LV EY+ Sbjct 116 LVVAIKKLNRQ-GLQGHKQWLAEVQFLGVVNHPNVVKLIGYCSEDGETGIERLLVYEYMS 174 Query 983 LGSLRDYL-PR--HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 SL D+L PR H++ + L EG+ YLH I+RD + NVLLD+ K+ Sbjct 175 NRSLEDHLFPRRSHTLPWKKRLEIMLGAAEGLTYLHDLKVIYRDFKSSNVLLDDQFCPKL 234 Query 1040 GDFGLAKAVPEGHEYY----RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 DFGLA+ P+G + RV G + APE ++ SDV+SFGV LYE++ Sbjct 235 SDFGLAREGPDGDNTHVTTARVGTHG-----YAAPEYVQTGHLRLKSDVYSFGVVLYEII 289 Query 1096 T--HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 T P + L + + R + +++ R P + L C + Sbjct 290 TGRRTIERNKPVAERRLLDWVKEYPADSQRFSMIVDPRLRNNYPAAGARSLAKLADLCLK 349 Query 1154 TEASFRPTFENLIPILKTVHEK 1175 RPT E ++ LK + E+ Sbjct 350 KNDKERPTMEIVVERLKKIIEE 371 >sp|P26619|PGFRA_XENLA Platelet-derived growth factor receptor alpha OS=Xenopus laevis OX=8355 GN=pdgfra PE=2 SV=1 Length=1087 Score = 107 bits (267), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 65/195 (33%), Positives = 101/195 (52%), Gaps = 19/195 (10%) Query 982 PLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 PL +++ L + + LL F Q+ GM +L +++ +HRDLAARNVLL + ++VK Sbjct 774 PLSEVKNILSDDGFEGLTVLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAHGKIVK 833 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 I DFGLA+ + Y + PV W APE + + + SDVWSFG+ L+E+ + Sbjct 834 ICDFGLARDIMHDSNYVS-KGSTFLPVKWMAPESIFDNLYTTLSDVWSFGILLWEIFS-- 890 Query 1099 DSSQSPPTKFLELIGIAQGQMTV-LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157 L G M V ++ G R+ +PD EVY +M CW +E Sbjct 891 ------------LGGTPYPGMIVDSTFYNKIKSGYRMAKPDHATHEVYDIMVKCWNSEPE 938 Query 1158 FRPTFENLIPILKTV 1172 RP+F +L I++++ Sbjct 939 KRPSFRHLSDIVESL 953 Score = 58.2 bits (139), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 45/166 (27%), Positives = 73/166 (44%), Gaps = 22/166 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L +KN VH ++ RN+LLA +K+ D G+ + V + Sbjct 801 QVARGMEFLASKNCVHRDLAARNVLLAH-------GKIVKICDFGLARDIMHDSNYVSKG 853 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + N +T D W FG L EI G P FY + Sbjct 854 STFLPVKWMAPESI--FDNLYTTLSDVWSFGILLWEIFSLGGTPYPGMIVDST--FYNKI 909 Query 830 --QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 +R+ +P + ++ + +C EP +RPSFR + + L P Sbjct 910 KSGYRMAKPDHATHEVYDIMVKCWNSEPEKRPSFRHLSDIVESLLP 955 >sp|P36888|FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 OS=Homo sapiens OX=9606 GN=FLT3 PE=1 SV=2 Length=993 Score = 107 bits (267), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 64/194 (33%), Positives = 101/194 (52%), Gaps = 18/194 (9%) Query 978 MEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037 +EY L + + + LL FA Q+ +GM +L + +HRDLAARNVL+ + ++V Sbjct 766 IEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVV 825 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 KI DFGLA+ + Y VR + PV W APE L E + SDVWS+G+ L+E+ + Sbjct 826 KICDFGLARDIMSDSNYV-VRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFS- 883 Query 1098 CDSSQSPPTKFLELIGIA--QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155 +G+ G +L++ G ++ +P E+Y +M++CW + Sbjct 884 --------------LGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFD 929 Query 1156 ASFRPTFENLIPIL 1169 + RP+F NL L Sbjct 930 SRKRPSFPNLTSFL 943 Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 54/209 (26%), Positives = 91/209 (44%), Gaps = 31/209 (15%) Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771 + A Q+A + +LE K+ VH ++ RN+L+ +K+ D G+ +S Sbjct 789 LCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTH-------GKVVKICDFGLARDIMSDSN 841 Query 772 RVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 V R + W+APE L G ++ + D W +G L EI G P P + + Sbjct 842 YVVRGNARLPVKWMAPESLFEGIYTIKS--DVWSYGILLWEIFSLGVNPYPG-IPVDA-N 897 Query 826 FY---QRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD---V 877 FY Q ++ +P + ++ + C ++ +RPSF +LT LAD Sbjct 898 FYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSF----PNLTSFLGCQLADAEEA 953 Query 878 LTVNPDSPASDP--TVFHKRYLKKIRDLG 904 + N D S+ T ++R + DLG Sbjct 954 MYQNVDGRVSECPHTYQNRRPFSREMDLG 982 >sp|Q5TCX8|M3K21_HUMAN Mitogen-activated protein kinase kinase kinase 21 OS=Homo sapiens OX=9606 GN=MAP3K21 PE=1 SV=3 Length=1036 Score = 107 bits (267), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 96/328 (29%), Positives = 151/328 (46%), Gaps = 74/328 (23%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW-----K 945 F + LK++ +G G FG+V + G+ VAVKA + D P+ + + Sbjct 120 AFERLELKEL--IGAGGFGQVYRATWQ------GQEVAVKAARQD--PEQDAAAAAESVR 169 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY---------------- 989 +E + L H +II+ +G C Q L LV+E+ G+L Sbjct 170 REARLFAMLRHPNIIELRGVCLQQPH--LCLVLEFARGGALNRALAAANAAPDPRAPGPR 227 Query 990 ----LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI---HRDLAARNVLL------DN--D 1034 +P H L+ +A QI GM YLH + ++ HRDL + N+LL D+ + Sbjct 228 RARRIPPHV-----LVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICN 282 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-WYAPECLKEYKFYYASDVWSFGVTLYE 1093 + +KI DFGLA+ E++R + + + W APE +K F SD+WS+GV L+E Sbjct 283 KTLKITDFGLAR------EWHRTTKMSTAGTYAWMAPEVIKSSLFSKGSDIWSYGVLLWE 336 Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 LLT P + ++ + +A G + V +LT LP P CP LMK CW+ Sbjct 337 LLTG-----EVPYRGIDGLAVAYG-VAVNKLT--------LPIPSTCPEPFAKLMKECWQ 382 Query 1154 TEASFRPTFENLIPILKTVHEKYQGQAP 1181 + RP+F ++ L + + P Sbjct 383 QDPHIRPSFALILEQLTAIEGAVMTEMP 410 Score = 53.9 bits (128), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 68/279 (24%), Positives = 104/279 (37%), Gaps = 61/279 (22%) Query 633 RGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 +GQE+ V DP A A A L + + H ++ + GVC++ P +V E+ Sbjct 144 QGQEVAVKAARQDPEQDAAAAAESVRREARLFAMLRHPNIIELRGVCLQQPHLCLVLEFA 203 Query 691 EHGPLDVWLRRERG-----------------HVPMAWKMVVAQQLASALSYLENKNLV-- 731 G L+ L HV + W A Q+A + YL + V Sbjct 204 RGGALNRALAAANAAPDPRAPGPRRARRIPPHVLVNW----AVQIARGMLYLHEEAFVPI 259 Query 732 -----------------HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 H ++C + + + GLA K+S G Sbjct 260 LHRDLKSSNILLLEKIEHDDICNKTLKITDFGLAREWHRTTKMSTAGT------------ 307 Query 775 RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRL 833 W+APE + ++ S D W +G L E+ GE P + + + L Sbjct 308 -YAWMAPEVI--KSSLFSKGSDIWSYGVLLWEL-LTGEVPYRGIDGLAVAYGVAVNKLTL 363 Query 834 PEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P PS CP+ A L +C +P RPSF IL LT ++ Sbjct 364 PIPSTCPEPFAKLMKECWQQDPHIRPSFALILEQLTAIE 402 >sp|Q9LFP7|PBL34_ARATH Serine/threonine-protein kinase PBL34 OS=Arabidopsis thaliana OX=3702 GN=PBL34 PE=1 SV=1 Length=493 Score = 105 bits (261), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 94/286 (33%), Positives = 134/286 (47%), Gaps = 28/286 (10%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LGEG FG V + P GTG VAVK L D G Q W EI+ L L H Sbjct 148 LGEGGFGCVFKGWIEENGTAPVKPGTGLTVAVKTLNPD-GLQGHKEWLAEINFLGNLLHP 206 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLH 1015 +++K G C + ++ LV E++P GSL ++L R S+ L + + A +G+++LH Sbjct 207 NLVKLVGYCIEDDQR--LLVYEFMPRGSLENHLFRRSLPLPWSIRMKIALGAAKGLSFLH 264 Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPE 1071 + I+RD N+LLD D K+ DFGLAK P EG + R G + APE Sbjct 265 EEALKPVIYRDFKTSNILLDADYNAKLSDFGLAKDAPDEGKTHVSTRVMGT--YGYAAPE 322 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQ-MTVLRLTELLE 1129 + SDV+SFGV L E+LT S ++ P L+ A+ + R LL+ Sbjct 323 YVMTGHLTSKSDVYSFGVVLLEMLTGRRSMDKNRPNGEHNLVEWARPHLLDKRRFYRLLD 382 Query 1130 RGERLPRPD-----KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 PR + K +V L C + RP +++ LK Sbjct 383 -----PRLEGHFSIKGAQKVTQLAAQCLSRDPKIRPKMSDVVEALK 423 Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 85/360 (24%), Positives = 146/360 (41%), Gaps = 67/360 (19%) Query 554 QP-GETSNLIIMRGARASPRT------LNLS----QLSFH--RVDQKEITQLSHLGQGTR 600 QP G+ S+ A +S T LN+S + +F+ ++ + S LG+G Sbjct 94 QPVGQVSSTTTTSNAESSSSTPVISEELNISSHLRKFTFNDLKLSTRNFRPESLLGEGGF 153 Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660 V++G + G+ P+ PG L V +K L+P + + Sbjct 154 GCVFKGWIEENGTA-----------PVKPGTG----LTVAVKTLNPDGLQGHKEWLAEIN 198 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 + + H +L + G C+ + ++V E++ G L+ L R +P + +M +A A Sbjct 199 FLGNLLHPNLVKLVGYCIEDDQRLLVYEFMPRGSLENHLFRRSLPLPWSIRMKIALGAAK 258 Query 721 ALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-----GALSREER 772 LS+L K +++ + NILL A KLSD G+ G R Sbjct 259 GLSFLHEEALKPVIYRDFKTSNILLDADYNA-------KLSDFGLAKDAPDEGKTHVSTR 311 Query 773 V-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ--- 828 V + APE + G L++ D + FG LLE+ G + P+ + + + Sbjct 312 VMGTYGYAAPEYVMTG--HLTSKSDVYSFGVVLLEM-LTGRRSMDKNRPNGEHNLVEWAR 368 Query 829 -------RQHRLPEP---------SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 R +RL +P ++ L +QCL+ +P RP ++ L L PH Sbjct 369 PHLLDKRRFYRLLDPRLEGHFSIKGAQKVTQLAAQCLSRDPKIRPKMSDVVEALKPL-PH 427 >sp|A2QHV0|SEPH_ASPNC Cytokinesis protein sepH OS=Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) OX=425011 GN=sepH PE=3 SV=1 Length=1336 Score = 107 bits (267), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 72/200 (36%), Positives = 101/200 (51%), Gaps = 23/200 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG+G FG V Y N TGE VAVK +K D EID+L+ L H +I+K Sbjct 65 LGKGAFGSV----YRALNWNTGETVAVKQIKLVDLPKSELRVIMLEIDLLKNLDHPNIVK 120 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY------LPRHSIGLAQLLLFAQQICEGMAYLH 1015 Y+G + ++L +++EY GSL P + +GL + Q+ G+ YLH Sbjct 121 YQGFV--KSAETLNIILEYCENGSLHSIAKNFGRFPENLVGL-----YMSQVLHGLLYLH 173 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 Q IHRD+ N+L + LVK+ DFG+A E V +P +W APE ++ Sbjct 174 EQGVIHRDIKGANILTTKEGLVKLADFGVASRTTGLSESSVV----GTP-YWMAPEVIEL 228 Query 1076 YKFYYASDVWSFGVTLYELL 1095 ASD+WS G T+ ELL Sbjct 229 SGATTASDIWSLGCTVIELL 248 Score = 63.9 bits (154), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 59/229 (26%), Positives = 99/229 (43%), Gaps = 18/229 (8%) Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 +K++D ++ + E L+ + H ++ G ++ EY E+G L + Sbjct 90 IKLVDLPKSELRVIMLEI-DLLKNLDHPNIVKYQGFVKSAETLNIILEYCENGSLHS-IA 147 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G P + Q+ L YL + ++H ++ G NIL + GL +KL+D Sbjct 148 KNFGRFPENLVGLYMSQVLHGLLYLHEQGVIHRDIKGANILTTKEGL-------VKLADF 200 Query 761 GVG--LGALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 GV LS V W+APE + GA +TA D W G T++E+ +G+ P + Sbjct 201 GVASRTTGLSESSVVGTPYWMAPEVIELSGA---TTASDIWSLGCTVIEL-LEGKPPYYN 256 Query 818 RSPSEKE-HFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 P H LP+ + P + QC +P R S R +L+ Sbjct 257 LQPMPALFRIVNDDHPPLPQGASPAVKDFLMQCFQKDPNLRVSARKLLK 305 >sp|Q54RR9|Y9844_DICDI Probable serine/threonine-protein kinase DDB_G0282963 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0282963 PE=3 SV=1 Length=1761 Score = 107 bits (267), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 75/287 (26%), Positives = 143/287 (50%), Gaps = 32/287 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I+ +G G F KV Y GE+VA+K LK + + +K+E DIL + +++ Sbjct 1479 IKKIGAGSFSKVYKAKY------MGEIVAIKVLKGEATSEQIELFKKEYDILSLVSSQNL 1532 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYLHAQ 1017 IK+ G C+ EK L++V EY GSL + + + ++ L+F Q +G+ LH Sbjct 1533 IKFYGACK---EKKLRMVTEYCQHGSLYHIMSKRKMDISWPLVFKWMHQAVDGINSLHTM 1589 Query 1018 H--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV----FWYAPE 1071 +HRD+ ++N+L+++ +K+ DFGLAK ++ +S + + APE Sbjct 1590 RPALVHRDIKSQNLLINSQFDLKVADFGLAKPT-------ELQTGSNSTIKGTMAYCAPE 1642 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLTELLE 1129 + +DV+S G+ L+E+ T + Q P E+ Q+ ++ + Sbjct 1643 LYNGISYSEKADVYSLGIVLWEITTRVITGKYQRPYEDNTEI--SFDFQIVIMS----SK 1696 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 +G R P P ++ +L++ CW + + RP+ + ++ + ++++ Y Sbjct 1697 QGIRPTMPPNVPPKLSYLIQKCWNQDPNERPSCQQILLAITSLYDDY 1743 Score = 43.1 bits (100), Expect = 0.023, Method: Compositional matrix adjust. Identities = 64/254 (25%), Positives = 108/254 (43%), Gaps = 37/254 (15%) Query 639 VVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +KVL + + I L F + ++S VS +L +G C + + MVTEY +HG L Sbjct 1500 VAIKVLKGEATSEQIEL-FKKEYDILSLVSSQNLIKFYGAC-KEKKLRMVTEYCQHGSLY 1557 Query 697 VWLRRERGHVPMAWKMVVA--QQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTS 752 + + + + ++W +V Q ++ L LVH ++ +N+L+ S Sbjct 1558 HIMSKRK--MDISWPLVFKWMHQAVDGINSLHTMRPALVHRDIKSQNLLI--------NS 1607 Query 753 PF-IKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 F +K++D G+ L S + + APE G S S D + G L EI Sbjct 1608 QFDLKVADFGLAKPTELQTGSNSTIKGTMAYCAPELYNGI--SYSEKADVYSLGIVLWEI 1665 Query 808 C---FDGEAPLQSRSPSEKEHFYQR---------QHRLPEPSCPQLATLTSQCLTYEPTQ 855 G+ +E +Q + +P P+L+ L +C +P + Sbjct 1666 TTRVITGKYQRPYEDNTEISFDFQIVIMSSKQGIRPTMPPNVPPKLSYLIQKCWNQDPNE 1725 Query 856 RPSFRTILRDLTRL 869 RPS + IL +T L Sbjct 1726 RPSCQQILLAITSL 1739 >sp|Q8AXC7|PGFRA_TAKRU Platelet-derived growth factor receptor alpha OS=Takifugu rubripes OX=31033 GN=pdgfra PE=3 SV=1 Length=1062 Score = 106 bits (265), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 65/203 (32%), Positives = 100/203 (49%), Gaps = 29/203 (14%) Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 LL F Q+ +GM +L +++ +HRDLAARNVLL ++VKI DFGLA+ + + Y + Sbjct 769 DLLSFTYQVAKGMEFLASKNCVHRDLAARNVLLSQGKIVKICDFGLARDIMHDNNYVS-K 827 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 PV W APE + + + SDVWS+G+ L+E+ + L G Sbjct 828 GSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFS--------------LGGTPYPG 873 Query 1119 MTV-LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV----- 1172 M V ++ G R+ +P+ P +VY +M CW +E RP+F L + ++ Sbjct 874 MIVDSSFYNKIKSGYRMSKPEHAPQDVYDMMMKCWNSEPEKRPSFLGLSDTIASLLPSSY 933 Query 1173 --------HEKYQGQAPSVFSVC 1187 HE + P+V VC Sbjct 934 KRHYERVNHEFLKSDHPAVTRVC 956 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 44/166 (27%), Positives = 73/166 (44%), Gaps = 22/166 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L +KN VH ++ RN+LL++ +K+ D G+ + V + Sbjct 776 QVAKGMEFLASKNCVHRDLAARNVLLSQ-------GKIVKICDFGLARDIMHDNNYVSKG 828 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + N +T D W +G L EI G P FY + Sbjct 829 STFLPVKWMAPESI--FDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMIVDSS--FYNKI 884 Query 830 --QHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 +R+ +P PQ + + +C EP +RPSF + + L P Sbjct 885 KSGYRMSKPEHAPQDVYDMMMKCWNSEPEKRPSFLGLSDTIASLLP 930 >sp|Q8VYG0|LRL13_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 1.3 OS=Arabidopsis thaliana OX=3702 GN=LRK10L-1.3 PE=2 SV=1 Length=686 Score = 105 bits (263), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 102/364 (28%), Positives = 164/364 (45%), Gaps = 28/364 (8%) Query 826 FYQRQHRLP-EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884 F +R+ +L + + L+T T Y + P+ TI L P + + S Sbjct 285 FIRRRKKLATQYTNKGLSTTTPYSSNYTMSNTPTSTTISGSNHSLVP----SISNLGNGS 340 Query 885 PASDPTVFHKRYLKKI-----RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 S VF L++ ++LG+G FG V Y DG VAVK L + + Sbjct 341 VYSGIQVFSYEELEEATENFSKELGDGGFGTVY---YGTLKDG--RAVAVKRL-FERSLK 394 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----- 994 +K EIDIL++L H +++ GC + + L LV EY+ G+L ++L + Sbjct 395 RVEQFKNEIDILKSLKHPNLVILYGC-TTRHSRELLLVYEYISNGTLAEHLHGNQAQSRP 453 Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 I L A + ++YLHA IHRD+ N+LLD++ VK+ DFGL++ P + Sbjct 454 ICWPARLQIAIETASALSYLHASGIIHRDVKTTNILLDSNYQVKVADFGLSRLFPMDQTH 513 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLEL 1111 G + PE + Y+ SDV+SFGV L EL++ D ++ L Sbjct 514 ISTAPQGTPG--YVDPEYYQCYRLNEKSDVYSFGVVLSELISSKEAVDITRHRHDINLAN 571 Query 1112 IGIAQGQM-TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + I++ Q V L +L R P K V L C + E RP+ + ++ +L+ Sbjct 572 MAISKIQNDAVHELADLSLGFARDPSVKKMMSSVAELAFRCLQQERDVRPSMDEIVEVLR 631 Query 1171 TVHE 1174 + + Sbjct 632 VIQK 635 Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 64/256 (25%), Positives = 109/256 (43%), Gaps = 48/256 (19%) Query 655 FYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDVWLRRERGHV-PMAW-- 710 F ++ + H +L ++G R E ++V EY+ +G L L + P+ W Sbjct 399 FKNEIDILKSLKHPNLVILYGCTTRHSRELLLVYEYISNGTLAEHLHGNQAQSRPICWPA 458 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 ++ +A + ASALSYL ++H +V NILL ++ +K++D G LSR Sbjct 459 RLQIAIETASALSYLHASGIIHRDVKTTNILL-------DSNYQVKVADFG-----LSRL 506 Query 771 ERVERIPW-LAPECLPGGAN-------SLSTAMDKWGFGATLLEICFDGEA--------- 813 +++ AP+ PG + L+ D + FG L E+ EA Sbjct 507 FPMDQTHISTAPQGTPGYVDPEYYQCYRLNEKSDVYSFGVVLSELISSKEAVDITRHRHD 566 Query 814 -PLQSRSPSEKEHFYQRQHRLP--------EPSCPQL----ATLTSQCLTYEPTQRPSFR 860 L + + S+ ++ H L +PS ++ A L +CL E RPS Sbjct 567 INLANMAISKIQN--DAVHELADLSLGFARDPSVKKMMSSVAELAFRCLQQERDVRPSMD 624 Query 861 TILRDLTRLQPHNLAD 876 I+ L +Q ++D Sbjct 625 EIVEVLRVIQKDGISD 640 >sp|Q5GIT4|VGFR2_DANRE Vascular endothelial growth factor receptor 2 OS=Danio rerio OX=7955 GN=kdr PE=1 SV=2 Length=1357 Score = 107 bits (266), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 63/172 (37%), Positives = 94/172 (55%), Gaps = 14/172 (8%) Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + + L+ ++ Q+ +GM +L ++ IHRDLAARN+LL + +VKI DFGLA+ V + +Y Sbjct 1011 LTMEDLISYSFQVAKGMEFLASRKCIHRDLAARNILLSENSVVKICDFGLARDVYKDPDY 1070 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 R + D P+ W APE + + + SDVWSFGV L+E+ + +S P G+ Sbjct 1071 VR-KGDARLPLKWMAPETIFDRVYTTQSDVWSFGVLLWEIFS-LGASPYP--------GV 1120 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + RL E G R+ PD E+Y M +CW RPTF L+ Sbjct 1121 CIDESFCRRLKE----GTRMRAPDYATPEIYQTMLDCWLDRPLDRPTFTQLV 1168 Score = 52.4 bits (124), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 62/257 (24%), Positives = 98/257 (38%), Gaps = 47/257 (18%) Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG--VCVRGPEN 683 P +P R R V + DP D+ L + T L G VC R E Sbjct 952 PRMPNR------REVQQDEDPREGDLGLG-----------TSTRLDICTGTAVCTRTGEQ 994 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 T E D W H+ M + + Q+A + +L ++ +H ++ RNILL+ Sbjct 995 TYKTLQDEQESSD-W-----DHLTMEDLISYSFQVAKGMEFLASRKCIHRDLAARNILLS 1048 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDK 797 + +K+ D G+ + V + + W+APE + +T D Sbjct 1049 E-------NSVVKICDFGLARDVYKDPDYVRKGDARLPLKWMAPETIFDRV--YTTQSDV 1099 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-----QHRLPEPSCPQLATLTSQCLTYE 852 W FG L EI G +P E F +R + R P+ + P++ C Sbjct 1100 WSFGVLLWEIFSLGASPYPGVCIDES--FCRRLKEGTRMRAPDYATPEIYQTMLDCWLDR 1157 Query 853 PTQRPSFRTILRDLTRL 869 P RP+F ++ L L Sbjct 1158 PLDRPTFTQLVEHLGNL 1174 >sp|Q8IR79|LIMK1_DROME LIM domain kinase 1 OS=Drosophila melanogaster OX=7227 GN=LIMK1 PE=1 SV=1 Length=1257 Score = 106 bits (265), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 74/228 (32%), Positives = 117/228 (51%), Gaps = 43/228 (19%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG FGKV + T+ +GE++ +K L +AD + + + +E+ +LR L H H++K Sbjct 407 LGEGFFGKV----FKVTHRQSGEVMVLKELHRAD--EEAQRNFIKEVAVLRLLDHRHVLK 460 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G +K L +V EYV G L++ + P + Q + A+ I GM+YLH+ + Sbjct 461 FIGVL--YKDKKLHMVTEYVAGGCLKELIHDPAQVLPWPQRVRLARDIACGMSYLHSMNI 518 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAV-----PEGHEY---YRVREDGDSPV------ 1065 IHRDL + N L+ DR V + DFGLA++V P G+ Y + D+P+ Sbjct 519 IHRDLNSMNCLVREDRSVIVADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMSPSGTL 578 Query 1066 ------------------FWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 +W APE +K K+ DV+SFG+ L E++ Sbjct 579 RRSKSRQRRQRYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEII 626 Score = 54.7 bits (130), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 67/276 (24%), Positives = 108/276 (39%), Gaps = 44/276 (16%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +VLK L + + F + +++ + H H+ GV + + MVTEYV G L Sbjct 427 MVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLYKDKKLHMVTEYVAGGCLKEL 486 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG--------RNILLARLGLAEG 750 + +P ++ +A+ +A +SYL + N++H ++ R++++A GLA Sbjct 487 IHDPAQVLPWPQRVRLARDIACGMSYLHSMNIIHRDLNSMNCLVREDRSVIVADFGLARS 546 Query 751 TS----PFIKLSDPGVGLGALSREER--------------------VERIPWLAPECLPG 786 P ++ G G GA S V W+APE + G Sbjct 547 VDAPRLPSGNMTPGGYGSGANSDAPMSPSGTLRRSKSRQRRQRYTVVGNPYWMAPEMMKG 606 Query 787 GANSLSTAMDKWGFGATLLEICFDGEA-----PLQSRSPSEKEHFYQR-QHRLPEPSCPQ 840 +D + FG L EI EA P S ++ F ++ + PEP Sbjct 607 L--KYDEKVDVFSFGIMLCEIIGRVEADPDFMPRNSDFSLNQQEFREKFCAQCPEP---- 660 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 + C P RP F T+ L RL AD Sbjct 661 FVKVAFVCCDLNPDMRPCFETLHVWLQRLADDLAAD 696 >sp|O14047|PPK11_SCHPO Serine/threonine-protein kinase ppk11 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ppk11 PE=3 SV=1 Length=312 Score = 101 bits (251), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 66/209 (32%), Positives = 101/209 (48%), Gaps = 16/209 (8%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 K + ++ +G+G FG V + + + ++VA+K + D QEI+ L Sbjct 1 MEKHQYRDLQLIGQGSFGSV----FRAQDVESSKIVALKVVDLDATKDQIETLTQEINFL 56 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEG 1010 L HI KY D L + MEY GS D L +++ +Q+ E Sbjct 57 IDLNSVHITKYYASFVDGFR--LWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEA 114 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---FW 1067 + YLH Q +HRD+ A N+L D LVK+ DFG++ + +R+ D V FW Sbjct 115 LVYLHGQGKMHRDIKAANILTMKDGLVKLADFGVSGQLES------LRDKNDDFVGTPFW 168 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096 APE +K+ + Y +D+WS G+T YEL T Sbjct 169 MAPEVVKQTGYNYKADIWSLGITAYELAT 197 Score = 40.4 bits (93), Expect = 0.080, Method: Compositional matrix adjust. Identities = 56/235 (24%), Positives = 88/235 (37%), Gaps = 33/235 (14%) Query 639 VVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LD 696 V LKV+D + D + + + ++ H+ + V G + EY + G LD Sbjct 32 VALKVVDLDATKDQIETLTQEINFLIDLNSVHITKYYASFVDGFRLWITMEYCDGGSCLD 91 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 L + G V +Q+ AL YL + +H ++ NIL + GL +K Sbjct 92 --LLKLSGTFSERVIAEVMRQVLEALVYLHGQGKMHRDIKAANILTMKDGL-------VK 142 Query 757 LSDPGVGLGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 L+D GV S ++ + W+APE + + D W G T E+ GE Sbjct 143 LADFGVSGQLESLRDKNDDFVGTPFWMAPEVVK--QTGYNYKADIWSLGITAYELA-TGE 199 Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQL---------ATLTSQCLTYEPTQRPS 858 P P + +P+ S P L S CL P R + Sbjct 200 PPYSGIHPMKVLLL------IPKHSPPSLERSKFSRAFCDFVSNCLKKNPKDRAT 248 >sp|Q8QHL3|VGFR1_CHICK Vascular endothelial growth factor receptor 1 OS=Gallus gallus OX=9031 GN=FLT1 PE=2 SV=1 Length=1327 Score = 106 bits (264), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 57/172 (33%), Positives = 94/172 (55%), Gaps = 14/172 (8%) Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + + L+ ++ Q+ GM +L ++ IHRDLAARN+LL + +VKI DFGLA+ + + +Y Sbjct 987 LTMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDY 1046 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 R + D P+ W APE + + + SDVWS+GV L+E+ + +S P + E Sbjct 1047 VR-KGDARLPLKWMAPESIFDKIYNTKSDVWSYGVLLWEIFS-LGASPYPGVQIDE---- 1100 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L+ G R+ P++ E+Y +M +CW + + RP F L+ Sbjct 1101 --------DFCSKLKEGTRMRAPEQATEEIYQIMLDCWRSNPNERPWFSELV 1144 Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust. Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 22/164 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V + Sbjct 998 QVARGMEFLSSRKCIHRDLAARNILLSE-------NNVVKICDFGLARDIYKNPDYVRKG 1050 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + +T D W +G L EI G +P E F + Sbjct 1051 DARLPLKWMAPESIFDKI--YNTKSDVWSYGVLLWEIFSLGASPYPGVQID--EDFCSKL 1106 Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + R PE + ++ + C P +RP F +++ L L Sbjct 1107 KEGTRMRAPEQATEEIYQIMLDCWRSNPNERPWFSELVKRLGDL 1150 >sp|Q54RZ7|Y1199_DICDI Probable serine/threonine-protein kinase DDB_G0282895 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0282895 PE=3 SV=1 Length=1634 Score = 106 bits (264), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 74/273 (27%), Positives = 131/273 (48%), Gaps = 26/273 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ ++ LGEG +V + G+ VAVK + +E+ IL + H Sbjct 1377 LQILQFLGEGALAEVHKGIWK------GKEVAVKIFNEGSFSFRLEDFLKEVAILGLISH 1430 Query 957 EHIIKYKGCC--EDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAY 1013 +++K KG C + + +V E + G+L + + ++ + L ++ +A + +G+AY Sbjct 1431 PNLLKLKGACIAPRSHKSTFMIVTELMHKGTLLEVINKNKPLSLEDIIKYALSVAQGLAY 1490 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 LH+ +IHRD+ A N+L+D + K+GDFGL++ + V +P W +PECL Sbjct 1491 LHSVDFIHRDIKAANILVDKNNNAKVGDFGLSRVIDNNFNMTAV---AGTPK-WESPECL 1546 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + ASDV+S+G+ L+EL T + FLE+ I + +V ++ + Sbjct 1547 MGEAYTSASDVYSYGMMLFELATGDE-------PFLEIQSIVELARSV------CDKKLK 1593 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 P + L+K+C RPT +I Sbjct 1594 PKISSSVPNFISSLIKDCLHNSPKKRPTMNQII 1626 Score = 61.6 bits (148), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 58/246 (24%), Positives = 116/246 (47%), Gaps = 25/246 (10%) Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPEN-----IMV 686 +G+E V +K+ + L F + +++ +SH +L + G C+ P + ++V Sbjct 1397 KGKE--VAVKIFNEGSFSFRLEDFLKEVAILGLISHPNLLKLKGACI-APRSHKSTFMIV 1453 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLAR 744 TE + G L + + + P++ + ++ A +A L+YL + + +H ++ NIL+ + Sbjct 1454 TELMHKGTLLEVINKNK---PLSLEDIIKYALSVAQGLAYLHSVDFIHRDIKAANILVDK 1510 Query 745 LGLAE-GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 A+ G ++ D + A++ + W +PECL G A ++A D + +G Sbjct 1511 NNNAKVGDFGLSRVIDNNFNMTAVAGTPK-----WESPECLMGEA--YTSASDVYSYGMM 1563 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE--PSCPQ-LATLTSQCLTYEPTQRPSFR 860 L E+ E L+ +S E + P+ S P +++L CL P +RP+ Sbjct 1564 LFELATGDEPFLEIQSIVELARSVCDKKLKPKISSSVPNFISSLIKDCLHNSPKKRPTMN 1623 Query 861 TILRDL 866 I++ L Sbjct 1624 QIIQKL 1629 >sp|Q5B4Z3|SEPH_EMENI Cytokinesis protein sepH OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=sepH PE=3 SV=2 Length=1346 Score = 106 bits (264), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 72/200 (36%), Positives = 100/200 (50%), Gaps = 23/200 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG G FG V Y N TGE VAVK +K AD EID+L+ L H +I+K Sbjct 66 LGRGAFGSV----YRALNWNTGETVAVKQIKLADLPKSELRVIMLEIDLLKNLDHPNIVK 121 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY------LPRHSIGLAQLLLFAQQICEGMAYLH 1015 Y+G + ++L +++EY GSL P +G+ + Q+ G+ YLH Sbjct 122 YQGFV--KSAETLNIILEYCENGSLHSIAKNFGRFPETLVGV-----YMSQVLHGLLYLH 174 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 Q IHRD+ N+L + LVK+ DFG+A E V +P +W APE ++ Sbjct 175 DQGVIHRDIKGANILTTKEGLVKLADFGVASRTTGLSESSVV----GTP-YWMAPEVIEL 229 Query 1076 YKFYYASDVWSFGVTLYELL 1095 ASD+WS G T+ ELL Sbjct 230 SGATTASDIWSLGCTVIELL 249 Score = 66.2 bits (160), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 62/234 (26%), Positives = 99/234 (42%), Gaps = 32/234 (14%) Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 ELRV++ +D L+ + H ++ G ++ EY E+G L Sbjct 100 ELRVIMLEID---------------LLKNLDHPNIVKYQGFVKSAETLNIILEYCENGSL 144 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 + + G P V Q+ L YL ++ ++H ++ G NIL + GL + Sbjct 145 HS-IAKNFGRFPETLVGVYMSQVLHGLLYLHDQGVIHRDIKGANILTTKEGL-------V 196 Query 756 KLSDPGVG--LGALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGATLLEICFDGE 812 KL+D GV LS V W+APE + GA +TA D W G T++E+ +G+ Sbjct 197 KLADFGVASRTTGLSESSVVGTPYWMAPEVIELSGA---TTASDIWSLGCTVIEL-LEGK 252 Query 813 APLQSRSPSEKE-HFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 P + P H LP+ + P + QC +P R S R +L+ Sbjct 253 PPYYNLQPMPALFRIVNDDHPPLPQGASPAVKDFLMQCFQKDPNLRVSARKLLK 306 >sp|Q9SRH7|PBL35_ARATH Serine/threonine-protein kinase PBL35 OS=Arabidopsis thaliana OX=3702 GN=PBL35 PE=1 SV=1 Length=490 Score = 103 bits (258), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 93/286 (33%), Positives = 135/286 (47%), Gaps = 28/286 (10%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LGEG FG V + P GTG VAVK L D G Q W EI+ L L H Sbjct 142 LGEGGFGCVFKGWVEENGTAPVKPGTGLTVAVKTLNPD-GLQGHKEWLAEINYLGNLLHP 200 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLH 1015 +++K G C + ++ LV E++P GSL ++L R S+ L + + A +G+++LH Sbjct 201 NLVKLVGYCIEDDQR--LLVYEFMPRGSLENHLFRRSLPLPWSIRMKIALGAAKGLSFLH 258 Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPE 1071 + I+RD N+LLD + K+ DFGLAK P EG + R G + APE Sbjct 259 EEALKPVIYRDFKTSNILLDGEYNAKLSDFGLAKDAPDEGKTHVSTRVMGT--YGYAAPE 316 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQ-MTVLRLTELLE 1129 + SDV+SFGV L E+LT S ++ P L+ A+ + R LL+ Sbjct 317 YVMTGHLTSKSDVYSFGVVLLEMLTGRRSMDKNRPNGEHNLVEWARPHLLDKRRFYRLLD 376 Query 1130 RGERLPRPD-----KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 PR + K +V L C ++ RP ++ +LK Sbjct 377 -----PRLEGHFSVKGAQKVTQLAAQCLSRDSKIRPKMSEVVEVLK 417 >sp|P53767|VGFR1_RAT Vascular endothelial growth factor receptor 1 OS=Rattus norvegicus OX=10116 GN=Flt1 PE=2 SV=1 Length=1336 Score = 105 bits (263), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 63/184 (34%), Positives = 98/184 (53%), Gaps = 16/184 (9%) Query 988 DY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 DY + + + + L+ ++ Q+ GM +L ++ IHRDLAARN+LL + +VKI DFGLA Sbjct 985 DYSEISKQPLTMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLA 1044 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + +Y R R D P+ W APE + + + SDVWS+GV L+E+ + S P Sbjct 1045 RDIYKNPDYVR-RGDTRLPLKWMAPESIFDKVYSTKSDVWSYGVLLWEIFS-LGGSPYP- 1101 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 G+ + RL E G R+ P+ E+Y +M +CW + RP F L Sbjct 1102 -------GVQMDEDFCSRLKE----GMRMRTPEYATPEIYQIMLDCWHKDPKERPRFAEL 1150 Query 1166 IPIL 1169 + L Sbjct 1151 VEKL 1154 Score = 54.7 bits (130), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 52/203 (26%), Positives = 83/203 (41%), Gaps = 33/203 (16%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V R Sbjct 1005 QVARGMEFLSSRKCIHRDLAARNILLSE-------NNVVKICDFGLARDIYKNPDYVRRG 1057 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + ST D W +G L EI G +P E F R Sbjct 1058 DTRLPLKWMAPESIFDKV--YSTKSDVWSYGVLLWEIFSLGGSPYPG--VQMDEDFCSRL 1113 Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN----------LA 875 + R PE + P++ + C +P +RP F ++ L L N L Sbjct 1114 KEGMRMRTPEYATPEIYQIMLDCWHKDPKERPRFAELVEKLGDLLQANVQQDGKDYIPLN 1173 Query 876 DVLTVNPDSPASDPTVFHKRYLK 898 +LT N S PT F + + K Sbjct 1174 AILTRNSGFTYSVPT-FSEDFFK 1195 Score = 45.1 bits (105), Expect = 0.006, Method: Compositional matrix adjust. Identities = 46/166 (28%), Positives = 65/166 (39%), Gaps = 17/166 (10%) Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV--NPDSPASDPTV------ 891 +L TLT C+ I R L R D L++ +PD D Sbjct 758 ELITLTCTCVAATLFWLLLTLFI-RKLKRSSSEVKTDYLSIIMDPDEVPLDEQCERLPYD 816 Query 892 -----FHKRYLKKIRDLGEGHFGK-VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 F + LK + LG G FGK V + T VAVK LK Sbjct 817 ASKWEFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALM 876 Query 946 QEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 E+ IL + +H +++ G C QG L +++EY G+L +YL Sbjct 877 TELKILTHIGHHLNVVNLLGACTKQG-GPLMVIVEYCKYGNLSNYL 921 >sp|O22042|M3K3_ARATH Mitogen-activated protein kinase kinase kinase 3 OS=Arabidopsis thaliana OX=3702 GN=ANP3 PE=1 SV=1 Length=651 Score = 104 bits (260), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 59/202 (29%), Positives = 107/202 (53%), Gaps = 15/202 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-------KADCGPQHRSGWKQEIDILRTLY 955 +G G FG+V Y N +GE++A+K + + H ++E+ +L+ L Sbjct 74 IGCGAFGRV----YMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLKNLS 129 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYL 1014 H +I++Y G + SL ++ME+VP GS+ L + S ++++ +Q+ G+ YL Sbjct 130 HPNIVRYLGTVRES--DSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLGLEYL 187 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H +HRD+ N+L+DN +++ DFG +K V E + +P +W APE + Sbjct 188 HNNGIMHRDIKGANILVDNKGCIRLADFGASKKVVELATVNGAKSMKGTP-YWMAPEVIL 246 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + +++D+WS G T+ E+ T Sbjct 247 QTGHSFSADIWSVGCTVIEMAT 268 Score = 53.9 bits (128), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 55/218 (25%), Positives = 96/218 (44%), Gaps = 21/218 (10%) Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 E L+ +SH ++ G ++ E+V G + L + G P ++ + Sbjct 120 EEVQLLKNLSHPNIVRYLGTVRESDSLNILMEFVPGGSISSLLEK-FGSFPEPVIIMYTK 178 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-----VGLGALSREE 771 QL L YL N ++H ++ G NIL+ G I+L+D G V L ++ + Sbjct 179 QLLLGLEYLHNNGIMHRDIKGANILVDNKGC-------IRLADFGASKKVVELATVNGAK 231 Query 772 RVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL--QSRSPSEKEHFYQ 828 ++ P W+APE + +S S D W G T++E+ G+ P Q + + H + Sbjct 232 SMKGTPYWMAPEVILQTGHSFSA--DIWSVGCTVIEMA-TGKPPWSEQYQQFAAVLHIGR 288 Query 829 RQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + +PE P+ +CL EP+ R S +L+ Sbjct 289 TKAHPPIPEDLSPEAKDFLMKCLHKEPSLRLSATELLQ 326 >sp|P35969|VGFR1_MOUSE Vascular endothelial growth factor receptor 1 OS=Mus musculus OX=10090 GN=Flt1 PE=1 SV=1 Length=1333 Score = 105 bits (263), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 63/184 (34%), Positives = 98/184 (53%), Gaps = 16/184 (9%) Query 988 DY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 DY + + + + L+ ++ Q+ GM +L ++ IHRDLAARN+LL + +VKI DFGLA Sbjct 985 DYSEISKQPLTMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLA 1044 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + +Y R R D P+ W APE + + + SDVWS+GV L+E+ + S P Sbjct 1045 RDIYKNPDYVR-RGDTRLPLKWMAPESIFDKVYSTKSDVWSYGVLLWEIFS-LGGSPYP- 1101 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 G+ + RL E G R+ P+ E+Y +M +CW + RP F L Sbjct 1102 -------GVQMDEDFCSRLKE----GMRMRTPEYATPEIYQIMLDCWHKDPKERPRFAEL 1150 Query 1166 IPIL 1169 + L Sbjct 1151 VEKL 1154 Score = 55.1 bits (131), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 50/195 (26%), Positives = 79/195 (41%), Gaps = 32/195 (16%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V R Sbjct 1005 QVARGMEFLSSRKCIHRDLAARNILLSE-------NNVVKICDFGLARDIYKNPDYVRRG 1057 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + ST D W +G L EI G +P E F R Sbjct 1058 DTRLPLKWMAPESIFDKV--YSTKSDVWSYGVLLWEIFSLGGSPYPG--VQMDEDFCSRL 1113 Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN----------LA 875 + R PE + P++ + C +P +RP F ++ L L N L Sbjct 1114 KEGMRMRTPEYATPEIYQIMLDCWHKDPKERPRFAELVEKLGDLLQANVQQDGKDYIPLN 1173 Query 876 DVLTVNPDSPASDPT 890 +LT N S PT Sbjct 1174 AILTRNSSFTYSTPT 1188 Score = 44.7 bits (104), Expect = 0.006, Method: Compositional matrix adjust. Identities = 46/166 (28%), Positives = 65/166 (39%), Gaps = 17/166 (10%) Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV--NPDSPASDPTV------ 891 +L TLT C+ I R L R D L++ +PD D Sbjct 759 ELITLTCTCVAATLFWLLLTLFI-RKLKRSSSEVKTDYLSIIMDPDEVPLDEQCERLPYD 817 Query 892 -----FHKRYLKKIRDLGEGHFGK-VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 F + LK + LG G FGK V + T VAVK LK Sbjct 818 ASKWEFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALM 877 Query 946 QEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 E+ IL + +H +++ G C QG L +++EY G+L +YL Sbjct 878 TELKILTHIGHHLNVVNLLGACTKQG-GPLMVIVEYCKYGNLSNYL 922 >sp|O01798|SPE8_CAEEL Spermatocyte protein spe-8 OS=Caenorhabditis elegans OX=6239 GN=spe-8 PE=1 SV=2 Length=512 Score = 103 bits (257), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 67/200 (34%), Positives = 107/200 (54%), Gaps = 11/200 (6%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG FG+V + VAVK L + + + +E +++ TL H ++ Sbjct 221 KKLGEGQFGEVHKGSLKTSVFAAPVTVAVKTLHQNHLSANEKILFLREANVMLTLSHPNV 280 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 IK+ G C ++ + +VME+ SL D L + +L+ G+ YLH + Sbjct 281 IKFYGVC--TMKEPIMIVMEFCDGKSLEDALLSKEEKVSAEDKILYLFHAACGIDYLHGK 338 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLA-KAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+AARN LL++ +++KI DFGL+ K V + R+ G PV + APE LK+ Sbjct 339 QVIHRDIAARNCLLNSKKILKISDFGLSVKGVA-----IKERKGGCLPVKYMAPETLKKG 393 Query 1077 KFYYASDVWSFGVTLYELLT 1096 + ASD++S+G +YE+ T Sbjct 394 LYSTASDIYSYGALMYEVYT 413 Score = 72.8 bits (177), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 67/292 (23%), Positives = 128/292 (44%), Gaps = 39/292 (13%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 +++ +++T LG+G V++G L+ P + V +K Sbjct 211 QLNNEQVTLNKKLGEGQFGEVHKGSLKTSVFAAP--------------------VTVAVK 250 Query 643 VLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 L +H + + F A++M +SH ++ +GVC ++V E+ + L+ L Sbjct 251 TLHQNHLSANEKILFLREANVMLTLSHPNVIKFYGVCTMKEPIMIVMEFCDGKSLEDALL 310 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + V K++ A + YL K ++H ++ RN LL + +K+SD Sbjct 311 SKEEKVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLL-------NSKKILKISDF 363 Query 761 GVGLGALSREERVER---IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 G+ + ++ +ER + ++APE L G STA D + +GA + E+ DG+ P ++ Sbjct 364 GLSVKGVAIKERKGGCLPVKYMAPETLKKGL--YSTASDIYSYGALMYEVYTDGKTPFET 421 Query 818 ---RSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILR 864 R ++ ++ L E P +A + Q YE R S + I++ Sbjct 422 CGLRGNELRKAIIGKRISLAVEVELPVFIANIFEQSRQYETEDRISSKQIIQ 473 >sp|Q55A09|Y9963_DICDI Probable serine/threonine-protein kinase DDB_G0272254 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0272254 PE=3 SV=1 Length=1331 Score = 105 bits (263), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 82/295 (28%), Positives = 136/295 (46%), Gaps = 40/295 (14%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR---S 942 +S T+ + +K +++G+GHF KV + G+ VAVK L ++ Sbjct 1062 SSSVTMINYSDIKIDKEIGKGHFSKV------LKGNWKGKDVAVKKLNSNKDKAREEMIQ 1115 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIG 996 +K E+++L +L H +++ C + +VME++P G+L + + + SI Sbjct 1116 EFKAEVELLGSLQHPNLV----TCYGYSLNPMCIVMEFLPSGNLFELIHSKPSEQQQSIK 1171 Query 997 LAQLLLFAQ--QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 L L+ A I GM +LH ++ IHRDL + N+L+D +KI D G+A+ Sbjct 1172 LDSTLILAIAFDIARGMQHLHTRNIIHRDLKSSNLLMDKHFNIKIADLGIARETSFTQTM 1231 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + V W APE L+ + +DV+S+ + LYELLT + Q GI Sbjct 1232 TTI-----GTVAWTAPEILRHESYNQKADVYSYAIVLYELLTGEEPYQ----------GI 1276 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 +L + +G R PD C L+ CW + + RP+FE + L Sbjct 1277 PPMNAGIL----VASKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITNYL 1327 Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust. Identities = 52/241 (22%), Positives = 92/241 (38%), Gaps = 35/241 (15%) Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D + ++ F L+ + H +L +G + +V E++ G L + + Sbjct 1107 DKAREEMIQEFKAEVELLGSLQHPNLVTCYGYSLN--PMCIVMEFLPSGNLFELIHSKPS 1164 Query 705 HVPMAWKM------VVAQQLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEG 750 + K+ +A +A + +L +N++H ++ N+L+ A LG+A Sbjct 1165 EQQQSIKLDSTLILAIAFDIARGMQHLHTRNIIHRDLKSSNLLMDKHFNIKIADLGIARE 1224 Query 751 TSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 TS ++ G + W APE L S + D + + L E+ Sbjct 1225 TSFTQTMTTIGT-------------VAWTAPEILR--HESYNQKADVYSYAIVLYEL-LT 1268 Query 811 GEAPLQSRSPSEKEHFYQRQH---RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 GE P Q P + LP+ P L C + +P +RPSF I LT Sbjct 1269 GEEPYQGIPPMNAGILVASKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITNYLT 1328 Query 868 R 868 + Sbjct 1329 K 1329 >sp|P10533|RMIL_AVII1 Serine/threonine-protein kinase-transforming protein Rmil OS=Avian retrovirus IC10 OX=11874 GN=V-RMIL PE=3 SV=1 Length=367 Score = 101 bits (252), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 79/277 (29%), Positives = 123/277 (44%), Gaps = 41/277 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK L PQ +K E+ +LR H +I+ Sbjct 73 IGSGSFGTV----YKGKWHGD---VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 125 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + L +V ++ SL +L + +L+ A+Q +GM YLHA+ Sbjct 126 FMGYST---KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSI 182 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPE---GHEYYRVREDGDSPVFWYAPECLK-- 1074 IHRDL + N+ L D VKIGDFGLA H++ E + W APE ++ Sbjct 183 IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQF----EQLSGSILWMAPEVIRMQ 238 Query 1075 -EYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 + + + SDV++FG+ LYEL+T + + + F+ G ++ +R Sbjct 239 DKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVR------ 292 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 CP + LM C + + RP F ++ Sbjct 293 --------SNCPKAMKRLMAECLKKKRDERPLFPQIL 321 Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 58/244 (24%), Positives = 103/244 (42%), Gaps = 24/244 (10%) Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +L V P+ + AF ++ + H ++ G + P+ +VT++ E L L Sbjct 94 MLNVTAPTPQQLQ-AFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHL 151 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 M + +A+Q A + YL K+++H ++ NI L +K+ D Sbjct 152 HIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE-------DLTVKIGD 204 Query 760 PGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGATLLEICFDGE 812 G+ G+ E+ I W+APE + N S D + FG L E+ G+ Sbjct 205 FGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYEL-MTGQ 263 Query 813 APLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQRPSFRTILRD 865 P + + ++ F R + P+ S CP+ + L ++CL + +RP F IL Sbjct 264 LPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILAS 323 Query 866 LTRL 869 + L Sbjct 324 IELL 327 >sp|Q4WXY0|BCK1_ASPFU Mitogen-activated protein kinase kinae kinase bck1 OS=Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) OX=330879 GN=bck1 PE=3 SV=1 Length=1617 Score = 105 bits (263), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 67/207 (32%), Positives = 109/207 (53%), Gaps = 23/207 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK---------ADCGPQHRSGWKQEIDILRT 953 +G+G +G+V L N GE++AVK ++ D + + QEID ++ Sbjct 1329 IGKGTYGRVYLGI----NADNGEVLAVKQVEINPRLAGQDTDRVKEMVAAMDQEIDTMQH 1384 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012 L H +I++Y GC ++GE S+ + +EY+ GS+ L +H + + +Q G+A Sbjct 1385 LEHPNIVQYLGC--ERGEFSISIYLEYISGGSIGSCLRKHGKFEESVVKSLTRQTLSGLA 1442 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE--GHEYYRVREDGDSPVFWYAP 1070 YLH Q +HRDL A N+LLD D KI DFG++K + G++ + VFW AP Sbjct 1443 YLHDQGILHRDLKADNILLDLDGTCKISDFGISKKTDDIYGNDSSNSMQGS---VFWMAP 1499 Query 1071 ECLKEYKFYYAS--DVWSFGVTLYELL 1095 E ++ Y++ D+WS G + E+ Sbjct 1500 EVIQSQGQGYSAKVDIWSLGCVVLEMF 1526 Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 44/172 (26%), Positives = 73/172 (42%), Gaps = 17/172 (10%) Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV-TEYVEHGPLDVWLRRERGHVPM 708 ++ A + M + H ++ G C RG +I + EY+ G + LR+ G Sbjct 1370 EMVAAMDQEIDTMQHLEHPNIVQYLG-CERGEFSISIYLEYISGGSIGSCLRKH-GKFEE 1427 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----- 763 + + +Q S L+YL ++ ++H ++ NILL G K+SD G+ Sbjct 1428 SVVKSLTRQTLSGLAYLHDQGILHRDLKADNILLDLDGT-------CKISDFGISKKTDD 1480 Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G S + W+APE + S +D W G +LE+ F G P Sbjct 1481 IYGNDSSNSMQGSVFWMAPEVIQSQGQGYSAKVDIWSLGCVVLEM-FAGRRP 1531 >sp|Q8I7I5|ROL3_CAEEL Protein roller-3 OS=Caenorhabditis elegans OX=6239 GN=rol-3 PE=1 SV=2 Length=2481 Score = 105 bits (263), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 75/270 (28%), Positives = 129/270 (48%), Gaps = 28/270 (10%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VA+K LK + Q + + +E +L L H +I+K G C G++ +++EY+ G+L Sbjct 1998 VAIKKLKPNHSFQEKMMFMKEAILLNNLDHPNIVKELGVCITPGQE--LILLEYMEGGNL 2055 Query 987 RDYLPRHSIGLAQ--------LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 +L + + Q LL + I GM YL ++H++L+AR LL V Sbjct 2056 LKFLQKSTPNEYQSSELSPRDLLSISVDIARGMNYLERLPHVHKNLSARKCLLAGRPGVT 2115 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 + G++K + G + R + V W APE LK+++F SDVW++GV LYE+ + Sbjct 2116 KLEMGMSKELSNG-QVNRSDLENMEIVRWMAPEVLKDFQFSSKSDVWAYGVLLYEVFSFG 2174 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE-VYHLMKNCWETEAS 1157 + + G R+ + G LP P CP + +Y ++K C ++++ Sbjct 2175 E--------------VPYGDKDNRRIMTDVRNGSVLPIPSYCPSKRIYKVIKQCLTSDST 2220 Query 1158 FRPTFENLIPILKTVHE--KYQGQAPSVFS 1185 R F ++ I +T + K Q P F+ Sbjct 2221 KRANFATILKIFETFRDDQKCQDDKPIQFN 2250 Score = 83.6 bits (205), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 71/247 (29%), Positives = 120/247 (49%), Gaps = 27/247 (11%) Query 635 QELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +++RV +K L P+H + F + A L++ + H ++ GVC+ + +++ EY+E G Sbjct 1994 KDVRVAIKKLKPNHSFQEKMMFMKEAILLNNLDHPNIVKELGVCITPGQELILLEYMEGG 2053 Query 694 PLDVWLRRERGHVPMAWK---------MVVAQQLASALSYLENKNLVHGNVCGRNILLA- 743 L +L++ P ++ + ++ +A ++YLE VH N+ R LLA Sbjct 2054 NLLKFLQKS---TPNEYQSSELSPRDLLSISVDIARGMNYLERLPHVHKNLSARKCLLAG 2110 Query 744 RLGLAE---GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800 R G+ + G S +LS+ V L E +E + W+APE L S+ D W + Sbjct 2111 RPGVTKLEMGMSK--ELSNGQVNRSDL---ENMEIVRWMAPEVLKDF--QFSSKSDVWAY 2163 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP--QLATLTSQCLTYEPTQRP 857 G L E+ GE P + + LP PS CP ++ + QCLT + T+R Sbjct 2164 GVLLYEVFSFGEVPYGDKDNRRIMTDVRNGSVLPIPSYCPSKRIYKVIKQCLTSDSTKRA 2223 Query 858 SFRTILR 864 +F TIL+ Sbjct 2224 NFATILK 2230 >sp|B0XXN8|BCK1_ASPFC Mitogen-activated protein kinase kinae kinase bck1 OS=Aspergillus fumigatus (strain CBS 144.89 / FGSC A1163 / CEA10) OX=451804 GN=bck1 PE=3 SV=1 Length=1617 Score = 105 bits (263), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 67/207 (32%), Positives = 109/207 (53%), Gaps = 23/207 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK---------ADCGPQHRSGWKQEIDILRT 953 +G+G +G+V L N GE++AVK ++ D + + QEID ++ Sbjct 1329 IGKGTYGRVYLGI----NADNGEVLAVKQVEINPRLAGQDTDRVKEMVAAMDQEIDTMQH 1384 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012 L H +I++Y GC ++GE S+ + +EY+ GS+ L +H + + +Q G+A Sbjct 1385 LEHPNIVQYLGC--ERGEFSISIYLEYISGGSIGSCLRKHGKFEESVVKSLTRQTLSGLA 1442 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE--GHEYYRVREDGDSPVFWYAP 1070 YLH Q +HRDL A N+LLD D KI DFG++K + G++ + VFW AP Sbjct 1443 YLHDQGILHRDLKADNILLDLDGTCKISDFGISKKTDDIYGNDSSNSMQGS---VFWMAP 1499 Query 1071 ECLKEYKFYYAS--DVWSFGVTLYELL 1095 E ++ Y++ D+WS G + E+ Sbjct 1500 EVIQSQGQGYSAKVDIWSLGCVVLEMF 1526 Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 44/172 (26%), Positives = 73/172 (42%), Gaps = 17/172 (10%) Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV-TEYVEHGPLDVWLRRERGHVPM 708 ++ A + M + H ++ G C RG +I + EY+ G + LR+ G Sbjct 1370 EMVAAMDQEIDTMQHLEHPNIVQYLG-CERGEFSISIYLEYISGGSIGSCLRKH-GKFEE 1427 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----- 763 + + +Q S L+YL ++ ++H ++ NILL G K+SD G+ Sbjct 1428 SVVKSLTRQTLSGLAYLHDQGILHRDLKADNILLDLDGT-------CKISDFGISKKTDD 1480 Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G S + W+APE + S +D W G +LE+ F G P Sbjct 1481 IYGNDSSNSMQGSVFWMAPEVIQSQGQGYSAKVDIWSLGCVVLEM-FAGRRP 1531 >sp|Q9DE49|PGFRA_DANRE Platelet-derived growth factor receptor alpha OS=Danio rerio OX=7955 GN=pdgfra PE=2 SV=1 Length=1059 Score = 105 bits (261), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 59/168 (35%), Positives = 88/168 (52%), Gaps = 16/168 (10%) Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 LL F Q+ GM +L +++ +HRDLAARNVLL ++VKI DFGLA+ + + Y + Sbjct 766 DLLSFTYQVARGMEFLASKNCVHRDLAARNVLLSQGKIVKICDFGLARDIMHDNNYVS-K 824 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 PV W APE + + + SDVWS+G+ L+E+ + L G Sbjct 825 GSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFS--------------LGGTPYPG 870 Query 1119 MTV-LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 M V ++ G R+ +P+ +VY LM CW +E RP+F +L Sbjct 871 MVVDSSFYNKIKSGYRMTKPEHASSDVYELMMKCWNSEPEKRPSFHSL 918 Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 44/166 (27%), Positives = 73/166 (44%), Gaps = 22/166 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L +KN VH ++ RN+LL++ +K+ D G+ + V + Sbjct 773 QVARGMEFLASKNCVHRDLAARNVLLSQ-------GKIVKICDFGLARDIMHDNNYVSKG 825 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + N +T D W +G L EI G P FY + Sbjct 826 STFLPVKWMAPESI--FDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMVVDSS--FYNKI 881 Query 830 --QHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 +R+ PE + + L +C EP +RPSF ++ + L P Sbjct 882 KSGYRMTKPEHASSDVYELMMKCWNSEPEKRPSFHSLSDTVASLLP 927 >sp|P23561|STE11_YEAST Serine/threonine-protein kinase STE11 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=STE11 PE=1 SV=3 Length=717 Score = 104 bits (259), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 53/155 (34%), Positives = 88/155 (57%), Gaps = 3/155 (2%) Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL 1002 + E+++L+ L+HE+I+ Y G ++ G +L + +EYVP GS+ L + L+ Sbjct 500 ALQHEMNLLKELHHENIVTYYGASQEGG--NLNIFLEYVPGGSVSSMLNNYGPFEESLIT 557 Query 1003 -FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 F +QI G+AYLH ++ IHRD+ N+L+D VKI DFG++K + ++ R Sbjct 558 NFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASL 617 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 VFW +PE +K+ +D+WS G + E+ T Sbjct 618 QGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFT 652 Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 39/177 (22%), Positives = 78/177 (44%), Gaps = 22/177 (12%) Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 H + A +L+ ++ H ++ +G G + EYV G + L + P Sbjct 494 HRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLN---NYGP 550 Query 708 MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763 ++ +Q+ ++YL KN++H ++ G NIL+ G +K++D G+ Sbjct 551 FEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGC-------VKITDFGISKK 603 Query 764 LGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 L L++++ + W++PE + A + D W G ++E+ F G+ P Sbjct 604 LSPLNKKQNKRASLQGSVFWMSPEVVKQTAT--TAKADIWSTGCVVIEM-FTGKHPF 657 >sp|A7A1P0|STE11_YEAS7 Serine/threonine-protein kinase STE11 OS=Saccharomyces cerevisiae (strain YJM789) OX=307796 GN=STE11 PE=3 SV=1 Length=717 Score = 104 bits (259), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 53/155 (34%), Positives = 88/155 (57%), Gaps = 3/155 (2%) Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL 1002 + E+++L+ L+HE+I+ Y G ++ G +L + +EYVP GS+ L + L+ Sbjct 500 ALQHEMNLLKELHHENIVTYYGASQEGG--NLNIFLEYVPGGSVSSMLNNYGPFEESLIT 557 Query 1003 -FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 F +QI G+AYLH ++ IHRD+ N+L+D VKI DFG++K + ++ R Sbjct 558 NFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASL 617 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 VFW +PE +K+ +D+WS G + E+ T Sbjct 618 QGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFT 652 Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 39/177 (22%), Positives = 78/177 (44%), Gaps = 22/177 (12%) Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 H + A +L+ ++ H ++ +G G + EYV G + L + P Sbjct 494 HRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLN---NYGP 550 Query 708 MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763 ++ +Q+ ++YL KN++H ++ G NIL+ G +K++D G+ Sbjct 551 FEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGC-------VKITDFGISKK 603 Query 764 LGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 L L++++ + W++PE + A + D W G ++E+ F G+ P Sbjct 604 LSPLNKKQNKRASLQGSVFWMSPEVVKQTAT--TAKADIWSTGCVVIEM-FTGKHPF 657 >sp|Q61846|MELK_MOUSE Maternal embryonic leucine zipper kinase OS=Mus musculus OX=10090 GN=Melk PE=1 SV=2 Length=643 Score = 103 bits (258), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 72/204 (35%), Positives = 111/204 (54%), Gaps = 12/204 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 +Y + +G G F KV L C+ T GEMVA+K + + K EID L++L Sbjct 9 KYYELYETIGTGGFAKVKLACHVLT----GEMVAIKIMDKNALGSDLPRVKTEIDALKSL 64 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAY 1013 H+HI + E + + + +V+EY P G L DY+ + + + + +QI +AY Sbjct 65 RHQHICQLYHVLETKNK--IFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAY 122 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +H+Q Y HRDL N+L D + +K+ DFGL A P+G++ Y ++ S + + APE L Sbjct 123 VHSQGYAHRDLKPENLLFDENHKLKLIDFGLC-AKPKGNKDYHLQTCCGS-LAYAAPE-L 179 Query 1074 KEYKFYYAS--DVWSFGVTLYELL 1095 + K Y S DVWS G+ LY L+ Sbjct 180 IQGKSYLGSEADVWSMGILLYVLM 203 >sp|Q54H45|DRKB_DICDI Probable serine/threonine-protein kinase drkB OS=Dictyostelium discoideum OX=44689 GN=drkB PE=3 SV=1 Length=690 Score = 104 bits (259), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 84/280 (30%), Positives = 136/280 (49%), Gaps = 36/280 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGT--GEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHI 959 +G+G+FG+V L GT G VAVK L A + + +EI++++ L H ++ Sbjct 397 IGKGNFGEVYL--------GTWRGSQVAVKKLPAHNINENILKEFHREINLMKNLRHPNV 448 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI--CEGMAYLHAQ 1017 I++ G C + + + EY+P GSL L I ++ L+ I +G+ YLH Sbjct 449 IQFLGSCLISPD--ICICTEYMPRGSLYSILHNEKIKISWSLVKRMMIDAAKGIIYLHGS 506 Query 1018 H--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRDL + N+L+D + VK+ DFGL+ +G +P W +PE L+ Sbjct 507 TPVILHRDLKSHNLLVDENWKVKVADFGLSTIEQQG----ATMTACGTPC-WTSPEVLRS 561 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 ++ +DV+SFG+ L+E C + Q P GI Q+ + + G R P Sbjct 562 QRYTEKADVYSFGIILWE----CATRQDP------YFGIPPFQV----IFAVGREGMRPP 607 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 P P + L+K+C S RPT E + IL+++ K Sbjct 608 TPKYGPPKYIQLLKDCLNENPSQRPTMEQCLEILESIETK 647 Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 62/262 (24%), Positives = 109/262 (42%), Gaps = 31/262 (12%) Query 630 GRDRGQELRVVLKVLDPSHH---DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 G RG + V +K L P+H+ +I F+ +LM + H ++ G C+ P+ + Sbjct 408 GTWRGSQ--VAVKKL-PAHNINENILKEFHREINLMKNLRHPNVIQFLGSCLISPDICIC 464 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQL--ASALSYLENKN--LVHGNVCGRNILL 742 TEY+ G L L E+ + ++W +V + A + YL ++H ++ N+L+ Sbjct 465 TEYMPRGSLYSILHNEK--IKISWSLVKRMMIDAAKGIIYLHGSTPVILHRDLKSHNLLV 522 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKW 798 + +K++D GL + ++ W +PE L + + D + Sbjct 523 DE-------NWKVKVAD--FGLSTIEQQGATMTACGTPCWTSPEVLR--SQRYTEKADVY 571 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSC--PQLATLTSQCLTYEPTQ 855 FG L E C + P P + R+ R P P P+ L CL P+Q Sbjct 572 SFGIILWE-CATRQDPYFGIPPFQVIFAVGREGMRPPTPKYGPPKYIQLLKDCLNENPSQ 630 Query 856 RPSFRTILRDLTRLQPHNLADV 877 RP+ L L ++ D+ Sbjct 631 RPTMEQCLEILESIETKGFDDI 652 >sp|O24527|SIK1_ARATH Serine/threonine-protein kinase 1 OS=Arabidopsis thaliana OX=3702 GN=SIK1 PE=1 SV=1 Length=836 Score = 104 bits (260), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 84/306 (27%), Positives = 136/306 (44%), Gaps = 31/306 (10%) Query 865 DLTRLQPHNLADVLTVNPDSPA-SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923 D ++Q N T PDS DPT ++ + +LG+G +G V Y + T Sbjct 220 DNRKMQQQNSKMSTTSLPDSITREDPTTKYEF----LNELGKGSYGSV----YKARDLKT 271 Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 E+VAVK + G + + EI++L+ H ++++Y G QGE L +VMEY Sbjct 272 SEIVAVKVISLTEGEEGYEEIRGEIEMLQQCNHPNVVRYLGSY--QGEDYLWIVMEYCGG 329 Query 984 GSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 GS+ D + ++ Q+ ++ +G+AYLH+ + +HRD+ N+LL VK+GD Sbjct 330 GSVADLMNVTEEALEEYQIAYICREALKGLAYLHSIYKVHRDIKGGNILLTEQGEVKLGD 389 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FG+A + R W APE ++E ++ DVW+ GV+ E+ Sbjct 390 FGVAAQLT---RTMSKRNTFIGTPHWMAPEVIQENRYDGKVDVWALGVSAIEMAEGLPPR 446 Query 1102 QSP-PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 S P + L +I I M L +K + + C E RP Sbjct 447 SSVHPMRVLFMISIEPAPM--------------LEDKEKWSLVFHDFVAKCLTKEPRLRP 492 Query 1161 TFENLI 1166 T ++ Sbjct 493 TAAEML 498 Score = 37.7 bits (86), Expect = 0.77, Method: Compositional matrix adjust. Identities = 41/162 (25%), Positives = 64/162 (40%), Gaps = 24/162 (15%) Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG---ALSRE 770 + ++ L+YL + VH ++ G NILL G +KL D GV +S+ Sbjct 351 ICREALKGLAYLHSIYKVHRDIKGGNILLTEQG-------EVKLGDFGVAAQLTRTMSKR 403 Query 771 ERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 P W+APE + N +D W G + +E+ +G P S P Sbjct 404 NTFIGTPHWMAPEVIQ--ENRYDGKVDVWALGVSAIEMA-EGLPPRSSVHPMRVLFMISI 460 Query 830 QHRLPEPSCPQ-------LATLTSQCLTYEPTQRPSFRTILR 864 + P P ++CLT EP RP+ +L+ Sbjct 461 E---PAPMLEDKEKWSLVFHDFVAKCLTKEPRLRPTAAEMLK 499 >sp|O08775|VGFR2_RAT Vascular endothelial growth factor receptor 2 OS=Rattus norvegicus OX=10116 GN=Kdr PE=1 SV=1 Length=1343 Score = 105 bits (261), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 69/197 (35%), Positives = 102/197 (52%), Gaps = 20/197 (10%) Query 971 EKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029 EKSL V E L +D+L L L+ ++ Q+ +GM +L ++ IHRDLAARN+ Sbjct 976 EKSLSDVEEEEASEELYKDFLT-----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNI 1030 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 LL +VKI DFGLA+ + + +Y R + D P+ W APE + + + S VWSFGV Sbjct 1031 LLSEKNVVKICDFGLARDIYKDPDYVR-KGDPRLPLKWMAPETIFDRIYTIQSGVWSFGV 1089 Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149 L+E+ + +S P K E + L+ G R+ PD E+Y M Sbjct 1090 LLWEIFS-LGASPYPGVKIDE------------KFCRRLKEGTRMRAPDYTTPEMYQTML 1136 Query 1150 NCWETEASFRPTFENLI 1166 +CW + + RP F L+ Sbjct 1137 DCWHEDPNQRPAFSELV 1153 Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 47/197 (24%), Positives = 85/197 (43%), Gaps = 34/197 (17%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V + Sbjct 1007 QVAKGMEFLASRKCIHRDLAARNILLSEKNV-------VKICDFGLARDIYKDPDYVRKG 1059 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + ++ + + W FG L EI G +P EK F +R Sbjct 1060 DPRLPLKWMAPETIFDRIYTIQSGV--WSFGVLLWEIFSLGASPYPGVKIDEK--FCRRL 1115 Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN------------ 873 + R P+ + P++ C +P QRP+F ++ L L N Sbjct 1116 KEGTRMRAPDYTTPEMYQTMLDCWHEDPNQRPAFSELVEHLGNLLQANAQQDGKDYIVLP 1175 Query 874 LADVLTVNPDSPASDPT 890 +++ L++ DS S PT Sbjct 1176 MSETLSMEEDSGLSLPT 1192 >sp|Q54RB7|SHKA_DICDI Dual specificity protein kinase shkA OS=Dictyostelium discoideum OX=44689 GN=shkA PE=2 SV=1 Length=527 Score = 103 bits (256), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 73/276 (26%), Positives = 127/276 (46%), Gaps = 29/276 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEM--VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG+G FG V G + VAVK + + + +++E+ I+ ++H +I+ Sbjct 51 LGDGSFGTVY--------KGRCRLKDVAVKVMLKQVDQKTLTDFRKEVAIMSKIFHPNIV 102 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 + G C K L + E + G+L L P + L + A+ G+ +LH+ + Sbjct 103 LFLGACTSTPGK-LMICTELMK-GNLESLLLDPMVKLPLITRMRMAKDAALGVLWLHSSN 160 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +IHRDL N+L+D + VK+ DFGL++ G ++ W APE L+ Sbjct 161 PVFIHRDLKTSNLLVDANLTVKVCDFGLSQIKQRGENLKDGQDGAKGTPLWMAPEVLQGR 220 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 F +DV+SFG+ L+++ T + F + I + Q+ R Sbjct 221 LFNEKADVYSFGLVLWQIFTRQELFPEFDNFFKFVAAICEKQL-------------RPSI 267 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 PD CP + L++ CW+ RP+FE ++ L+ + Sbjct 268 PDDCPKSLKELIQKCWDPNPEVRPSFEGIVSELEEI 303 Score = 62.0 bits (149), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 71/299 (24%), Positives = 125/299 (42%), Gaps = 48/299 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + + EIT S LG G+ VY+GR R++ ++V+LK Sbjct 40 ISETEITTESILGDGSFGTVYKGRCRLKDVA----------------------VKVMLKQ 77 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 +D F + ++MS++ H ++ G C P +M+ + G L+ L Sbjct 78 VD---QKTLTDFRKEVAIMSKIFHPNIVLFLGACTSTPGKLMICTELMKGNLESLLLDPM 134 Query 704 GHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILL-ARLGLAEGTSPFIKLSDP 760 +P+ +M +A+ A + +L + N +H ++ N+L+ A L + ++ Sbjct 135 VKLPLITRMRMAKDAALGVLWLHSSNPVFIHRDLKTSNLLVDANLTVKVCDFGLSQIKQR 194 Query 761 GVGLGALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 G L ++ + P W+APE L G + D + FG L +I Q Sbjct 195 GENLK--DGQDGAKGTPLWMAPEVLQG--RLFNEKADVYSFGLVLWQI-----FTRQELF 245 Query 820 PSEKEHFY-------QRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 P E ++F+ ++Q R P CP+ L L +C P RPSF I+ +L + Sbjct 246 P-EFDNFFKFVAAICEKQLRPSIPDDCPKSLKELIQKCWDPNPEVRPSFEGIVSELEEI 303 >sp|P35917|VGFR3_MOUSE Vascular endothelial growth factor receptor 3 OS=Mus musculus OX=10090 GN=Flt4 PE=1 SV=1 Length=1363 Score = 104 bits (260), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 58/175 (33%), Positives = 94/175 (54%), Gaps = 14/175 (8%) Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + + L+ ++ Q+ GM +L ++ IHRDLAARN+LL +VKI DFGLA+ + + +Y Sbjct 1009 LTMEDLVCYSFQVARGMEFLASRKCIHRDLAARNILLSESDIVKICDFGLARDIYKDPDY 1068 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 R + P+ W APE + + + SDVWSFGV L+E+ + +S P + E Sbjct 1069 VR-KGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFS-LGASPYPGVQINE---- 1122 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + L+ G R+ P+ + H+M++CW + RP F +L+ IL Sbjct 1123 --------EFCQRLKDGTRMRAPELATPAIRHIMQSCWSGDPKARPAFSDLVEIL 1169 Score = 56.6 bits (135), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 43/164 (26%), Positives = 73/164 (45%), Gaps = 22/164 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L ++ +H ++ RNILL+ S +K+ D G+ + V + Sbjct 1020 QVARGMEFLASRKCIHRDLAARNILLSE-------SDIVKICDFGLARDIYKDPDYVRKG 1072 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + +T D W FG L EI G +P +E+ F QR Sbjct 1073 SARLPLKWMAPESIFDKV--YTTQSDVWSFGVLLWEIFSLGASPYPGVQINEE--FCQRL 1128 Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + R PE + P + + C + +P RP+F ++ L L Sbjct 1129 KDGTRMRAPELATPAIRHIMQSCWSGDPKARPAFSDLVEILGDL 1172 >sp|Q91ZT1|VGFR3_RAT Vascular endothelial growth factor receptor 3 OS=Rattus norvegicus OX=10116 GN=Flt4 PE=1 SV=1 Length=1363 Score = 104 bits (260), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 58/175 (33%), Positives = 94/175 (54%), Gaps = 14/175 (8%) Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + + L+ ++ Q+ GM +L ++ IHRDLAARN+LL +VKI DFGLA+ + + +Y Sbjct 1009 LTMEDLVCYSFQVARGMEFLASRKCIHRDLAARNILLSESDIVKICDFGLARDIYKDPDY 1068 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 R + P+ W APE + + + SDVWSFGV L+E+ + +S P + E Sbjct 1069 VR-KGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFS-LGASPYPGVQINE---- 1122 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + L+ G R+ P+ + H+M++CW + RP F +L+ IL Sbjct 1123 --------EFCQRLKDGTRMRAPELATPAIRHIMQSCWSGDPKARPAFSDLVEIL 1169 Score = 56.6 bits (135), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 43/164 (26%), Positives = 73/164 (45%), Gaps = 22/164 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L ++ +H ++ RNILL+ S +K+ D G+ + V + Sbjct 1020 QVARGMEFLASRKCIHRDLAARNILLSE-------SDIVKICDFGLARDIYKDPDYVRKG 1072 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + +T D W FG L EI G +P +E+ F QR Sbjct 1073 SARLPLKWMAPESIFDKV--YTTQSDVWSFGVLLWEIFSLGASPYPGVQINEE--FCQRL 1128 Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + R PE + P + + C + +P RP+F ++ L L Sbjct 1129 KDGTRMRAPELATPAIRHIMQSCWSGDPKARPAFSDLVEILGDL 1172 >sp|Q10056|SHK2_SCHPO Serine/threonine-protein kinase shk2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=shk2 PE=3 SV=1 Length=589 Score = 103 bits (257), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 78/249 (31%), Positives = 122/249 (49%), Gaps = 17/249 (7%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS-DPTVFHKRYLKKIRDLGEGH 907 +T P + S T+ R +T Q L + DS S DP Y LG+G Sbjct 270 VTKVPVKADSKNTLSRRMTDRQA------LAMLKDSVTSHDPV----EYFNVKHKLGQGA 319 Query 908 FGKVSL-YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC 966 G V L G + VA+K++ C + + EI ++R H +I+ Y Sbjct 320 SGSVYLAKVVGGKQLGIFDSVAIKSIDLQCQTR-KELILNEITVMRESIHPNIVTYLDSF 378 Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 + E+ L +VMEY+ GSL D + + + AQ+ + C+G+ +LHA++ IHRD+ + Sbjct 379 LVR-ERHLWVVMEYMNAGSLTDIIEKSKLTEAQIARICLETCKGIQHLHARNIIHRDIKS 437 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 NVLLDN +KI DFG A RV G +P +W APE +K+ ++ D+WS Sbjct 438 DNVLLDNSGNIKITDFGFC-ARLSNRTNKRVTMVG-TP-YWMAPEVVKQNEYGTKVDIWS 494 Query 1087 FGVTLYELL 1095 G+ + E++ Sbjct 495 LGIMIIEMI 503 Score = 43.9 bits (102), Expect = 0.009, Method: Compositional matrix adjust. Identities = 57/278 (21%), Positives = 105/278 (38%), Gaps = 40/278 (14%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LGQG +VY ++ V G+ G V +K +D Sbjct 315 LGQGASGSVYLAKV-------------------VGGKQLGIFDSVAIKSIDLQCQTRKEL 355 Query 655 FYETASLMSQVSHTHL-AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 ++M + H ++ ++ VR +V EY+ G L + E+ + A Sbjct 356 ILNEITVMRESIHPNIVTYLDSFLVRERHLWVVMEYMNAGSLTDII--EKSKLTEAQIAR 413 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-EER 772 + + + +L +N++H ++ N+LL G IK++D G +R +R Sbjct 414 ICLETCKGIQHLHARNIIHRDIKSDNVLLDNSG-------NIKITDFGFCARLSNRTNKR 466 Query 773 VERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 V + W+APE + N T +D W G ++E+ + E P P + + Sbjct 467 VTMVGTPYWMAPEVVK--QNEYGTKVDIWSLGIMIIEM-IENEPPYLREDPIRALYLIAK 523 Query 830 QH----RLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 + P L + + CLT + R + +L Sbjct 524 NGTPTLKKPNLVSKNLKSFLNSCLTIDTIFRATAAELL 561 >sp|Q55FT4|TSUA_DICDI Probable serine/threonine-protein kinase tsuA OS=Dictyostelium discoideum OX=44689 GN=tsuA PE=1 SV=1 Length=2247 Score = 105 bits (261), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 67/203 (33%), Positives = 106/203 (52%), Gaps = 16/203 (8%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYH 956 K I +GEG FGKV Y TG++VA K + K + +QEIDIL+ L H Sbjct 6 KLIGQIGEGSFGKV----YKYRKKFTGQLVACKVISKKGKNEEDILSLRQEIDILKNLSH 61 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAY 1013 +II++ C E++ E LV EY G L + S+ L Q + + Q+ + Y Sbjct 62 PNIIQFISCFENKNE--FTLVTEYAD-GDLSQIISEEKTLSVDLIQSICY--QLVIALNY 116 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 LH + IHRD+ +N+L+ + +K+ DFG AK + + +P++ APE + Sbjct 117 LHYKKVIHRDIKPQNILITSGGQIKVCDFGFAKTISSNS--ILLTSLKGTPLYL-APEII 173 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 +E + Y +D+WS G+ LY++L Sbjct 174 QEQPYDYKADLWSLGIILYQILV 196 Score = 40.4 bits (93), Expect = 0.15, Method: Compositional matrix adjust. Identities = 49/211 (23%), Positives = 84/211 (40%), Gaps = 19/211 (9%) Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 L+ + ++ +SH ++ E +VTEY + G L + E+ + + Sbjct 47 LSLRQEIDILKNLSHPNIIQFISCFENKNEFTLVTEYAD-GDLSQIISEEKT-LSVDLIQ 104 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 + QL AL+YL K ++H ++ +NIL+ G IK+ D G S Sbjct 105 SICYQLVIALNYLHYKKVIHRDIKPQNILITSGGQ-------IKVCDFGFAKTISSNSIL 157 Query 773 VERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF-Y 827 + + +LAPE + D W G L +I G P + S ++ H Sbjct 158 LTSLKGTPLYLAPEII--QEQPYDYKADLWSLGIILYQILV-GSPPFSANSLADLVHMTL 214 Query 828 QRQHRLPEP--SCPQLATLTSQCLTYEPTQR 856 + +P+ P L +L Q L P +R Sbjct 215 ESNIEIPKELNKYPDLVSLFRQLLCKNPDKR 245 >sp|P27636|CDC15_YEAST Cell division control protein 15 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CDC15 PE=1 SV=3 Length=974 Score = 104 bits (259), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 77/238 (32%), Positives = 119/238 (50%), Gaps = 26/238 (11%) Query 872 HNLADVLTVN--PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 +++AD VN P AS+ +V + +LK++ +G G +G V Y N T ++VA+ Sbjct 2 NSMADTDRVNLTPIQRASEKSV--QYHLKQV--IGRGSYGVV----YKAINKHTDQVVAI 53 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K + + + + EI +L+ L H +I+KY G E L +++EY GSLR Sbjct 54 KEVVYE-NDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYE--LYILLEYCANGSLRRL 110 Query 990 LPRHSIGLAQ--LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 + R S GL++ + Q G+ YLH + IHRD+ A N+LL D VK+ DFG++ Sbjct 111 ISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTI 170 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 V + W APE L SD+WS G T+ E+LT ++PP Sbjct 171 VNSSALTLA------GTLNWMAPEILGNRGASTLSDIWSLGATVVEMLT-----KNPP 217 Score = 60.1 bits (144), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 51/207 (25%), Positives = 88/207 (43%), Gaps = 12/207 (6%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 SL+ ++H ++ HG + E ++ EY +G L + R + Q Sbjct 72 SLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTL 131 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPW 778 L YL + ++H ++ NILL+ A+ T +KL+D GV S + + W Sbjct 132 LGLKYLHGEGVIHRDIKAANILLS----ADNT---VKLADFGVSTIVNSSALTLAGTLNW 184 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838 +APE L G ST D W GAT++E+ P + + + + + P S Sbjct 185 MAPEIL--GNRGASTLSDIWSLGATVVEM-LTKNPPYHNLTDANIYYAVENDTYYPPSSF 241 Query 839 PQ-LATLTSQCLTYEPTQRPSFRTILR 864 + L S+C +RP+ +L+ Sbjct 242 SEPLKDFLSKCFVKNMYKRPTADQLLK 268 >sp|Q00342|FLT3_MOUSE Receptor-type tyrosine-protein kinase FLT3 OS=Mus musculus OX=10090 GN=Flt3 PE=1 SV=2 Length=1000 Score = 104 bits (259), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 60/177 (34%), Positives = 94/177 (53%), Gaps = 18/177 (10%) Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + LL FA Q+ +GM +L + +HRDLAARNVL+ + ++VKI DFGLA+ + Y Sbjct 786 LTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDILSDSSY 845 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 VR + PV W APE L E + SDVWS+G+ L+E+ + +G+ Sbjct 846 V-VRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFS---------------LGV 889 Query 1115 A--QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 G +L++ G ++ +P +Y +M++CW ++ RP+F NL L Sbjct 890 NPYPGIPVDANFYKLIQSGFKMEQPFYATEGIYFVMQSCWAFDSRKRPSFPNLTSFL 946 Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 42/159 (26%), Positives = 71/159 (45%), Gaps = 22/159 (14%) Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771 + A Q+A + +LE K+ VH ++ RN+L+ +K+ D G+ LS Sbjct 792 LCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTH-------GKVVKICDFGLARDILSDSS 844 Query 772 RVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 V R + W+APE L G ++ + D W +G L EI G P P + + Sbjct 845 YVVRGNARLPVKWMAPESLFEGIYTIKS--DVWSYGILLWEIFSLGVNPYPG-IPVDA-N 900 Query 826 FY---QRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSF 859 FY Q ++ +P + + + C ++ +RPSF Sbjct 901 FYKLIQSGFKMEQPFYATEGIYFVMQSCWAFDSRKRPSF 939 >sp|P00532|RAF_MSV36 Serine/threonine-protein kinase-transforming protein raf OS=Murine sarcoma virus 3611 OX=11812 GN=V-RAF PE=3 SV=1 Length=323 Score = 99.8 bits (247), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 79/276 (29%), Positives = 127/276 (46%), Gaps = 39/276 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+ Sbjct 30 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILL 82 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ Sbjct 83 FMGYMT---KDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 139 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076 IHRD+ + N+ L VKIGDFGLA +V + S V W APE ++ + Sbjct 140 IHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-VLWMAPEVIRMQDDN 198 Query 1077 KFYYASDVWSFGVTLYELL------THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 F + SDV+S+G+ LYEL+ H ++ + + ++G + RL + Sbjct 199 PFSFQSDVYSYGIVLYELMAGELPYAHINNRD----QIIFMVGRGYASPDLSRLYK---- 250 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 CP + L+ +C + RP F ++ Sbjct 251 --------NCPKAIKRLVADCVKKVKEERPLFPQIL 278 Score = 62.8 bits (151), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 67/269 (25%), Positives = 119/269 (44%), Gaps = 27/269 (10%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688 G+ G +LKV+DP+ + AF +++ + H ++ G + +N+ +VT+ Sbjct 41 GKWHGDVAVKILKVVDPTPEQLQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 97 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + E L L + M + +A+Q A + YL KN++H ++ NI L Sbjct 98 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF-----LH 152 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECL-PGGANSLSTAMDKWGFG 801 EG + +K+ D G+ G+ E+ + W+APE + N S D + +G Sbjct 153 EGLT--VKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYG 210 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQ-RQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854 L E+ GE P + ++ F R + P+ S CP+ + L + C+ Sbjct 211 IVLYEL-MAGELPYAHINNRDQIIFMVGRGYASPDLSRLYKNCPKAIKRLVADCVKKVKE 269 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPD 883 +RP F IL + LQ H+L + P+ Sbjct 270 ERPLFPQILSSIELLQ-HSLPKINRSAPE 297 >sp|F4JPX3|PBL20_ARATH Probable serine/threonine-protein kinase PBL20 OS=Arabidopsis thaliana OX=3702 GN=PBL20 PE=3 SV=1 Length=388 Score = 100 bits (250), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 96/296 (32%), Positives = 133/296 (45%), Gaps = 30/296 (10%) Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR--PSFRTILRDLTRLQPHN 873 +SR EKE R + S P+L T + PT R PS T ++DL + N Sbjct 13 KSRGNMEKEKKNIRGREFLQKSAPELTTRKTTLSFNLPTPRSLPS-PTSIKDLYTDREQN 71 Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE------MV 927 L V SD T R LK +GEG FG S+Y N G+ V Sbjct 72 QNQNLRVFSFKELSDATCEFSRKLK----IGEGGFG--SVYKATINNPTVGDSHSSPLTV 125 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 AVK L H+ W E+ L + H ++++ G C + E+ LV E + SL Sbjct 126 AVKKLNRQSLQGHKQ-WLAEVHFLGVVNHPNVVRLLGYCSEDRER--LLVYELMSNRSLE 182 Query 988 DYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L ++ Q L +G+AYLH I+RD + NVLL+ + K+ DFGL Sbjct 183 DHLFTLRTLTLSWKQRLEIMLGAAQGLAYLHEIQVIYRDFKSSNVLLNEEFHPKLSDFGL 242 Query 1045 AKAVPEGHEYY----RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 A+ PEG + RV DG + APE + DV+SFGV LYE++T Sbjct 243 AREGPEGDNTHVTTARVGTDG-----YAAPEYVITGHLKTHCDVYSFGVVLYEIIT 293 >sp|B5VNQ3|STE11_YEAS6 Serine/threonine-protein kinase STE11 OS=Saccharomyces cerevisiae (strain AWRI1631) OX=545124 GN=STE11 PE=3 SV=2 Length=717 Score = 103 bits (257), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 53/153 (35%), Positives = 87/153 (57%), Gaps = 3/153 (2%) Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-F 1003 + E+++L+ L+HE+I+ Y G ++ G +L + +EYVP GS+ L + L+ F Sbjct 502 QHEMNLLKELHHENIVTYYGASQEGG--NLNIFLEYVPGGSVSSMLNNYGPFEESLITNF 559 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 +QI G+AYLH + IHRD+ N+L+D VKI DFG++K + ++ R Sbjct 560 TRQILIGVAYLHKKKIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQG 619 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 VFW +PE +K+ +D+WS G + E+ T Sbjct 620 SVFWMSPEVVKQSATTAKADIWSTGCVVIEMFT 652 Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust. Identities = 38/177 (21%), Positives = 77/177 (44%), Gaps = 22/177 (12%) Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 H + A +L+ ++ H ++ +G G + EYV G + L + P Sbjct 494 HRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLN---NYGP 550 Query 708 MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763 ++ +Q+ ++YL K ++H ++ G NIL+ G +K++D G+ Sbjct 551 FEESLITNFTRQILIGVAYLHKKKIIHRDIKGANILIDIKGC-------VKITDFGISKK 603 Query 764 LGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 L L++++ + W++PE + A + D W G ++E+ F G+ P Sbjct 604 LSPLNKKQNKRASLQGSVFWMSPEVVKQSAT--TAKADIWSTGCVVIEM-FTGKHPF 657 >sp|Q9SII6|PIX13_ARATH Probable serine/threonine-protein kinase PIX13 OS=Arabidopsis thaliana OX=3702 GN=PIX13 PE=1 SV=2 Length=414 Score = 101 bits (251), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 91/291 (31%), Positives = 133/291 (46%), Gaps = 18/291 (6%) Query 895 RYLKKIRDLGEGHFGKVS---LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 R + LGEG FGKV L P G ++AVK L A+ Q W+ E++ L Sbjct 85 RNFRSENVLGEGGFGKVFKGWLEDKTPGKQSNGTVIAVKKLNAESF-QGFEEWQCEVNFL 143 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQ 1006 + H +++K G C + E L LV EY+ GSL ++L R + L L A Sbjct 144 GRVSHPNLVKLLGYCLEGEE--LLLVYEYMQKGSLENHLFRKGSAVQPLSWEIRLKIAIG 201 Query 1007 ICEGMAYLHA--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE-YYRVREDGDS 1063 +G+A+LHA + I+RD A N+LLD KI DFGLAK P + + R G Sbjct 202 AAKGLAFLHASEKQVIYRDFKASNILLDGSYNAKISDFGLAKLGPSASQSHITTRVMGTH 261 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVL 1122 + APE + Y SDV+ FGV L E+LT + + PT L + ++ Sbjct 262 G--YAAPEYVATGHLYVKSDVYGFGVVLAEILTGLHALDPTRPTGQHNLTEWIKPHLSER 319 Query 1123 R-LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 R L +++ P K V L C E RP+ + ++ L+ + Sbjct 320 RKLRSIMDPRLEGKYPFKSAFRVAQLALKCLGPEPKNRPSMKEVVESLELI 370 Score = 68.2 bits (165), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 82/314 (26%), Positives = 137/314 (44%), Gaps = 42/314 (13%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 I L+ L TR E L G G +G ++D+ PG+ + + +K L+ Sbjct 74 IFSLAELRASTRNFRSENVLGEGGFGKVFKGWLEDK---TPGKQSNGTV-IAVKKLNAES 129 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV-P 707 + + + +VSH +L + G C+ G E ++V EY++ G L+ L R+ V P Sbjct 130 FQGFEEWQCEVNFLGRVSHPNLVKLLGYCLEGEELLLVYEYMQKGSLENHLFRKGSAVQP 189 Query 708 MAW--KMVVAQQLASALSYL--ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 ++W ++ +A A L++L K +++ + NILL S K+SD G+ Sbjct 190 LSWEIRLKIAIGAAKGLAFLHASEKQVIYRDFKASNILL-------DGSYNAKISDFGLA 242 Query 764 -LG-ALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGE 812 LG + S+ R+ + APE + G L D +GFG L EI D Sbjct 243 KLGPSASQSHITTRVMGTHGYAAPEYVATG--HLYVKSDVYGFGVVLAEILTGLHALDPT 300 Query 813 APLQSRSPSE--KEHFYQRQH-----------RLPEPSCPQLATLTSQCLTYEPTQRPSF 859 P + +E K H +R+ + P S ++A L +CL EP RPS Sbjct 301 RPTGQHNLTEWIKPHLSERRKLRSIMDPRLEGKYPFKSAFRVAQLALKCLGPEPKNRPSM 360 Query 860 RTILRDLTRLQPHN 873 + ++ L ++ N Sbjct 361 KEVVESLELIEAAN 374 >sp|Q12852|M3K12_HUMAN Mitogen-activated protein kinase kinase kinase 12 OS=Homo sapiens OX=9606 GN=MAP3K12 PE=1 SV=2 Length=859 Score = 103 bits (258), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 79/262 (30%), Positives = 116/262 (44%), Gaps = 37/262 (14%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 GE VAVK + R + +I LR L H +II +KG C ++ME+ Sbjct 146 GEEVAVKKV--------RDLKETDIKHLRKLKHPNIITFKGVCTQA--PCYCILMEFCAQ 195 Query 984 GSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 G L + L + + L+ ++ I GM YLH IHRDL + N+L+ D +VKI DF Sbjct 196 GQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDF 255 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 G +K + + + V W APE ++ D+WSFGV L+ELLT Sbjct 256 GTSKELSD----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLT-----G 306 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 P K ++ I G + LP P CP L++ CW ++ RP+F Sbjct 307 EIPYKDVDSSAIIWG---------VGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSF 357 Query 1163 ENLI--------PILKTVHEKY 1176 ++ +L T E Y Sbjct 358 RQILLHLDIASADVLSTPQETY 379 Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 71/260 (27%), Positives = 106/260 (41%), Gaps = 36/260 (14%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 GR G+E+ V KV D DI + ++ H ++ GVC + P ++ E+ Sbjct 142 GRFHGEEV-AVKKVRDLKETDI--------KHLRKLKHPNIITFKGVCTQAPCYCILMEF 192 Query 690 VEHGPLDVWLRRERGHVP---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 G L LR R P + W M +A ++YL ++H ++ N+L+ Sbjct 193 CAQGQLYEVLRAGRPVTPSLLVDWSMGIA----GGMNYLHLHKIIHRDLKSPNMLIT--- 245 Query 747 LAEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +K+SD G + ++ + W+APE + +S +D W FG Sbjct 246 ----YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 299 Query 804 LLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFR 860 L E+ GE P + S LP PS CP L QC +P RPSFR Sbjct 300 LWEL-LTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFR 358 Query 861 TILRDLTRLQPHNLADVLTV 880 IL L ADVL+ Sbjct 359 QILLHLDIAS----ADVLST 374 >sp|Q60700|M3K12_MOUSE Mitogen-activated protein kinase kinase kinase 12 OS=Mus musculus OX=10090 GN=Map3k12 PE=1 SV=1 Length=888 Score = 103 bits (258), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 79/262 (30%), Positives = 116/262 (44%), Gaps = 37/262 (14%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 GE VAVK + R + +I LR L H +II +KG C ++ME+ Sbjct 179 GEEVAVKKV--------RDLKETDIKHLRKLKHPNIITFKGVCTQA--PCYCILMEFCAQ 228 Query 984 GSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 G L + L + + L+ ++ I GM YLH IHRDL + N+L+ D +VKI DF Sbjct 229 GQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDF 288 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 G +K + + + V W APE ++ D+WSFGV L+ELLT Sbjct 289 GTSKELSD----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG----- 339 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 P K ++ I G + LP P CP L++ CW ++ RP+F Sbjct 340 EIPYKDVDSSAIIWG---------VGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSF 390 Query 1163 ENLI--------PILKTVHEKY 1176 ++ +L T E Y Sbjct 391 RQILLHLDIASADVLSTPQETY 412 Score = 63.5 bits (153), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 71/260 (27%), Positives = 106/260 (41%), Gaps = 36/260 (14%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 GR G+E+ V KV D DI + ++ H ++ GVC + P ++ E+ Sbjct 175 GRFHGEEV-AVKKVRDLKETDI--------KHLRKLKHPNIITFKGVCTQAPCYCILMEF 225 Query 690 VEHGPLDVWLRRERGHVP---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 G L LR R P + W M +A ++YL ++H ++ N+L+ Sbjct 226 CAQGQLYEVLRAGRPVTPSLLVDWSMGIA----GGMNYLHLHKIIHRDLKSPNMLIT--- 278 Query 747 LAEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +K+SD G + ++ + W+APE + +S +D W FG Sbjct 279 ----YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 332 Query 804 LLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFR 860 L E+ GE P + S LP PS CP L QC +P RPSFR Sbjct 333 LWEL-LTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFR 391 Query 861 TILRDLTRLQPHNLADVLTV 880 IL L ADVL+ Sbjct 392 QILLHLDIAS----ADVLST 407 >sp|P17948|VGFR1_HUMAN Vascular endothelial growth factor receptor 1 OS=Homo sapiens OX=9606 GN=FLT1 PE=1 SV=2 Length=1338 Score = 104 bits (259), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 62/182 (34%), Positives = 96/182 (53%), Gaps = 14/182 (8%) Query 988 DYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 D + I + L+ ++ Q+ GM +L ++ IHRDLAARN+LL + +VKI DFGLA+ Sbjct 987 DGFYKEPITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLARD 1046 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + + +Y R + D P+ W APE + + + SDVWS+GV L+E+ + S P Sbjct 1047 IYKNPDYVR-KGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFS-LGGSPYP--- 1101 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 G+ + RL E G R+ P+ E+Y +M +CW + RP F L+ Sbjct 1102 -----GVQMDEDFCSRLRE----GMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVE 1152 Query 1168 IL 1169 L Sbjct 1153 KL 1154 Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 43/169 (25%), Positives = 72/169 (43%), Gaps = 22/169 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ + V + Sbjct 1005 QVARGMEFLSSRKCIHRDLAARNILLSENNV-------VKICDFGLARDIYKNPDYVRKG 1057 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + ST D W +G L EI G +P E F R Sbjct 1058 DTRLPLKWMAPESIFDKI--YSTKSDVWSYGVLLWEIFSLGGSPYPG--VQMDEDFCSRL 1113 Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 + R PE S P++ + C +P +RP F ++ L L N+ Sbjct 1114 REGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQANV 1162 Score = 44.3 bits (103), Expect = 0.010, Method: Compositional matrix adjust. Identities = 45/166 (27%), Positives = 65/166 (39%), Gaps = 17/166 (10%) Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV--NPDSPASDPTV------ 891 +L TLT C+ I R + R D L++ +PD D Sbjct 758 ELITLTCTCVAATLFWLLLTLFI-RKMKRSSSEIKTDYLSIIMDPDEVPLDEQCERLPYD 816 Query 892 -----FHKRYLKKIRDLGEGHFGK-VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 F + LK + LG G FGK V + T VAVK LK Sbjct 817 ASKWEFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALM 876 Query 946 QEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 E+ IL + +H +++ G C QG L +++EY G+L +YL Sbjct 877 TELKILTHIGHHLNVVNLLGACTKQG-GPLMVIVEYCKYGNLSNYL 921 >sp|A7J1T2|M313A_XENLA Mitogen-activated protein kinase kinase kinase 13-A OS=Xenopus laevis OX=8355 GN=map3k13-a PE=2 SV=1 Length=961 Score = 103 bits (258), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 85/273 (31%), Positives = 122/273 (45%), Gaps = 39/273 (14%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI--LRTL 954 + +++ LG G G V L + GE VA+K ++ ++E DI LR L Sbjct 169 ISELQWLGSGAQGAVFLGKF------RGEEVAIKKVRE----------QKETDIKHLRKL 212 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAY 1013 H +II +KG C L+MEY G L + L +LL+ ++ I GM Y Sbjct 213 KHPNIIAFKGVCTQA--PCYCLIMEYCAHGQLYEVLRAGRKVSPRLLVDWSNGIASGMNY 270 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 LH IHRDL + NVL+ + VKI DFG +K + + + V W APE + Sbjct 271 LHLHKIIHRDLKSPNVLVTHTDTVKISDFGTSKELSDK----STKMSFAGTVAWMAPEVI 326 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + D+WSFGV L+ELLT P K ++ I G + Sbjct 327 RNEPVSEKVDIWSFGVLLWELLT-----GEIPYKDVDSSAIIWG---------VGSNSLH 372 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 LP P CP LMK W ++ RP+F ++ Sbjct 373 LPVPSTCPDGFKILMKQTWHSKPRNRPSFRQIL 405 Score = 66.2 bits (160), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 77/308 (25%), Positives = 123/308 (40%), Gaps = 54/308 (18%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 +A L Q V +EI++L LG G + V+ G+ R Sbjct 147 GKAYSTDYKLQQQETWEVPFEEISELQWLGSGAQGAVFLGKFR----------------- 189 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 G+E+ + KV + DI + ++ H ++ GVC + P ++ Sbjct 190 -------GEEV-AIKKVREQKETDIKH--------LRKLKHPNIIAFKGVCTQAPCYCLI 233 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLAR 744 EY HG L LR R P +++V + +AS ++YL ++H ++ N+L+ Sbjct 234 MEYCAHGQLYEVLRAGRKVSP---RLLVDWSNGIASGMNYLHLHKIIHRDLKSPNVLVTH 290 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFG 801 + +K+SD G + ++ + W+APE + +S +D W FG Sbjct 291 -------TDTVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFG 341 Query 802 ATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPS 858 L E+ GE P + S LP PS CP L Q +P RPS Sbjct 342 VLLWEL-LTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWHSKPRNRPS 400 Query 859 FRTILRDL 866 FR IL L Sbjct 401 FRQILMHL 408 >sp|P00531|MIL_AVIMH Serine/threonine-protein kinase-transforming protein mil OS=Avian retrovirus MH2 OX=11870 GN=V-MIL PE=3 SV=1 Length=380 Score = 100 bits (249), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 68/200 (34%), Positives = 102/200 (51%), Gaps = 17/200 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+ Sbjct 88 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILL 140 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ Sbjct 141 FMGYMT---KDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 197 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076 IHRD+ + N+ L VKIGDFGLA +V + S + W APE ++ Sbjct 198 IHRDMKSNNIFLHGGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-ILWMAPEVIRMQDSN 256 Query 1077 KFYYASDVWSFGVTLYELLT 1096 F + SDV+S+G+ LYEL+T Sbjct 257 PFSFQSDVYSYGIVLYELMT 276 Score = 64.7 bits (156), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 72/286 (25%), Positives = 126/286 (44%), Gaps = 32/286 (11%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688 G+ G +LKV+DP+ AF +++ + H ++ G + +N+ +VT+ Sbjct 99 GKWHGDVAVKILKVVDPTPEQFQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 155 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + E L L + M + +A+Q A + YL KN++H ++ NI L GL Sbjct 156 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFL-HGGLT 214 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFG 801 +K+ D G+ G+ E+ I W+APE + +N S D + +G Sbjct 215 ------VKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYG 268 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854 L E+ GE P + ++ F R + P+ S CP+ + L + CL Sbjct 269 IVLYEL-MTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVRE 327 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 +RP F IL + LQ H+L + + AS+P++ + + I Sbjct 328 ERPLFPQILSSIALLQ-HSLPKI-----NRSASEPSLHRASHTEDI 367 >sp|Q8GXZ3|PBL8_ARATH Probable serine/threonine-protein kinase PBL8 OS=Arabidopsis thaliana OX=3702 GN=PBL8 PE=1 SV=1 Length=410 Score = 100 bits (249), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 81/230 (35%), Positives = 118/230 (51%), Gaps = 14/230 (6%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LGEG FG V Y D G + VAVK L + HR W E++ L L H +++ Sbjct 75 LGEGGFGTVYKGYIDDNLRVGLKSLPVAVKVLNKEGLQGHRE-WLTEVNFLGQLRHPNLV 133 Query 961 KYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA 1016 K G CCED LV E++ GSL ++L R + + ++ ++ A +G+A+LH Sbjct 134 KLIGYCCEDDHR---LLVYEFMLRGSLENHLFRKTTAPLSWSRRMMIALGAAKGLAFLHN 190 Query 1017 QH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 I+RD N+LLD+D K+ DFGLAKA P+G E + V + APE + Sbjct 191 AERPVIYRDFKTSNILLDSDYTAKLSDFGLAKAGPQGDETH-VSTRVMGTYGYAAPEYVM 249 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR 1123 SDV+SFGV L E+LT S ++ P+K L+ A+ ++ R Sbjct 250 TGHLTARSDVYSFGVVLLEMLTGRKSVDKTRPSKEQNLVDWARPKLNDKR 299 Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 60/265 (23%), Positives = 109/265 (41%), Gaps = 40/265 (15%) Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 + L V +KVL+ + + + Q+ H +L + G C ++V E++ G Sbjct 97 KSLPVAVKVLNKEGLQGHREWLTEVNFLGQLRHPNLVKLIGYCCEDDHRLLVYEFMLRGS 156 Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGLAEG 750 L+ L R + P++W +M++A A L++L N + +++ + NILL Sbjct 157 LENHLFR-KTTAPLSWSRRMMIALGAAKGLAFLHNAERPVIYRDFKTSNILL-------D 208 Query 751 TSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 + KLSD G+ +E + + APE + G L+ D + FG L Sbjct 209 SDYTAKLSDFGLAKAGPQGDETHVSTRVMGTYGYAAPEYVMTG--HLTARSDVYSFGVVL 266 Query 805 LEICFDGEAPLQSRSPSEKEHFY-------QRQHRLPEPSCPQL------------ATLT 845 LE+ G + PS++++ + +L + P+L +L Sbjct 267 LEM-LTGRKSVDKTRPSKEQNLVDWARPKLNDKRKLLQIIDPRLENQYSVRAAQKACSLA 325 Query 846 SQCLTYEPTQRPSFRTILRDLTRLQ 870 CL+ P RP ++ L LQ Sbjct 326 YYCLSQNPKARPLMSDVVETLEPLQ 350 >sp|P11346|KRAF1_DROME Raf homolog serine/threonine-protein kinase Raf OS=Drosophila melanogaster OX=7227 GN=Raf PE=1 SV=6 Length=739 Score = 103 bits (256), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 81/277 (29%), Positives = 127/277 (46%), Gaps = 29/277 (10%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHII 960 +G G FG V + + P VAVK L P +K E+ +L+ H +I+ Sbjct 435 IGSGSFGTVYRAHWHGP--------VAVKTLNVKTPSPAQLQAFKNEVAMLKKTRHCNIL 486 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 + GC + SL +V ++ SL ++ L L+ +Q+ +GM YLHA++ Sbjct 487 LFMGCV---SKPSLAIVTQWCEGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYLHAKN 543 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK- 1077 IHRDL + N+ L D VKIGDFGLA A + + S + W APE ++ + Sbjct 544 IIHRDLKSNNIFLHEDLSVKIGDFGLATAKTRWSGEKQANQPTGS-ILWMAPEVIRMQEL 602 Query 1078 --FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + + SDV++FG+ +YELL C K L + +G LL Sbjct 603 NPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRG---------LLRPDMSQV 653 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 R D P + L ++C + RP F L+ +L+ + Sbjct 654 RSD-APQALKRLAEDCIKYTPKDRPLFRPLLNMLENM 689 Score = 54.3 bits (129), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 58/245 (24%), Positives = 97/245 (40%), Gaps = 26/245 (11%) Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 L V PS + AF +++ + H ++ G CV P +VT++ E L + Sbjct 456 TLNVKTPSPAQLQ-AFKNEVAMLKKTRHCNILLFMG-CVSKPSLAIVTQWCEGSSLYKHV 513 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + + + +Q+A + YL KN++H ++ NI L E S +K+ D Sbjct 514 HVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSNNIF-----LHEDLS--VKIGD 566 Query 760 PGVGLGAL--SREERVER----IPWLAPECLPGGA-NSLSTAMDKWGFGATLLEICFDGE 812 G+ S E++ + I W+APE + N S D + FG + E+ E Sbjct 567 FGLATAKTRWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELL--AE 624 Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQ--------LATLTSQCLTYEPTQRPSFRTILR 864 ++ + + L P Q L L C+ Y P RP FR +L Sbjct 625 CLPYGHISNKDQILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLN 684 Query 865 DLTRL 869 L + Sbjct 685 MLENM 689 >sp|O22040|ANP1_ARATH Mitogen-activated protein kinase kinase kinase ANP1 OS=Arabidopsis thaliana OX=3702 GN=ANP1 PE=1 SV=2 Length=666 Score = 102 bits (255), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 70/274 (26%), Positives = 125/274 (46%), Gaps = 32/274 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-------KADCGPQHRSGWKQEIDILRTLY 955 +G G FG V Y N +GE++AVK + + H ++E+ +L+ L Sbjct 75 IGRGAFGTV----YMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLS 130 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYL 1014 H +I++Y G + + +L +++E+VP GS+ L + + + + +Q+ G+ YL Sbjct 131 HPNIVRYLGTVRE--DDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYL 188 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H +HRD+ N+L+DN +K+ DFG +K V E + +P +W APE + Sbjct 189 HNHAIMHRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTP-YWMAPEVIL 247 Query 1075 EYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + +++D+WS G T+ E++T S Q + IG + Sbjct 248 QTGHSFSADIWSVGCTVIEMVTGKAPWSQQYKEVAAIFFIGTTKSHP------------- 294 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 P PD + + C + + RPT L+ Sbjct 295 --PIPDTLSSDAKDFLLKCLQEVPNLRPTASELL 326 Score = 53.1 bits (126), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 52/218 (24%), Positives = 90/218 (41%), Gaps = 21/218 (10%) Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 E L+ +SH ++ G ++ E+V G + L + G P + + Sbjct 121 EEVKLLKNLSHPNIVRYLGTVREDDTLNILLEFVPGGSISSLLEK-FGPFPESVVRTYTR 179 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-----LGALSREE 771 QL L YL N ++H ++ G NIL+ G IKL+D G L ++ + Sbjct 180 QLLLGLEYLHNHAIMHRDIKGANILVDNKGC-------IKLADFGASKQVAELATMTGAK 232 Query 772 RVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 ++ P W+APE + +S S D W G T++E+ G+AP + F+ Sbjct 233 SMKGTPYWMAPEVILQTGHSFSA--DIWSVGCTVIEMVT-GKAPWSQQYKEVAAIFFIGT 289 Query 831 HR----LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + +P+ +CL P RP+ +L+ Sbjct 290 TKSHPPIPDTLSSDAKDFLLKCLQEVPNLRPTASELLK 327 >sp|Q7T6Y2|YR831_MIMIV Putative serine/threonine-protein kinase/receptor R831 OS=Acanthamoeba polyphaga mimivirus OX=212035 GN=MIMI_R831 PE=3 SV=2 Length=1624 Score = 103 bits (258), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 85/279 (30%), Positives = 134/279 (48%), Gaps = 31/279 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G +G+V Y GT V + + K RS + +E+ I+ +L H +++ + Sbjct 792 LGTGGYGEV----YKSIWKGTEVAVKLISSKHVSKDMERSFF-EEVKIMTSLRHPNVVLF 846 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQHY 1019 ++ +VME++ LGSL D L I A + A Q +GM +LH+ Sbjct 847 MAAS--TKSPNMCIVMEFMSLGSLYDLLGNELIPEIPYALKIKMAYQASKGMHFLHSSGI 904 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK-- 1077 +HRDL + N+LLD+ VK+ DFGL K E + + ++ + W APE L + Sbjct 905 VHRDLKSLNLLLDSKWNVKVSDFGLTKVKSE-LDKKKTNDNIIGTIHWIAPEILNDSTEV 963 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 Y +DV+SFG+ L+ELLT + P K + IA ++V+R G R P Sbjct 964 DYILADVYSFGIILWELLT-----REQPYKGMTPAAIA---VSVIR------DGMRPPIS 1009 Query 1138 DKC----PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 D+ E L+K CW ++ RPTF ++ L + Sbjct 1010 DEAVTAHSIEYIDLIKQCWHSDTIIRPTFLEIMTRLSNI 1048 Score = 100 bits (249), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 80/264 (30%), Positives = 124/264 (47%), Gaps = 37/264 (14%) Query 924 GEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982 G VAVK +K ++ E+ L L H +I+ + G C + ++ +V EY+ Sbjct 1385 GVDVAVKKFVKQKLSETQLLEFRAEMAFLSELKHSNIVTFIGACIKK--PNICIVTEYMR 1442 Query 983 LGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDNDRLVK 1038 +G+LRD L P I A L G+ YLH+ + +HRD+ N+L+D VK Sbjct 1443 MGNLRDVLKNPDIKITFANKLKLLYGAAMGIDYLHSSNPMIVHRDIKPANILVDEHFNVK 1502 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPV-----FWYAPECLKEYKFYYASDVWSFGVTLYE 1093 I DFG A R++ED + W APE ++ K+ +DV+SFGV ++E Sbjct 1503 IADFGFA----------RIKEDNTTMTRCGTPCWTAPEVIRGEKYCEKADVFSFGVVMWE 1552 Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 +LT + P A+ + L ++LE G R P CP E L+K CW Sbjct 1553 VLT----GKEP---------FAECNFMKVSL-DILEGG-RPIIPSDCPHEFAKLIKKCWH 1597 Query 1154 TEASFRPTFENLIPILKTVHEKYQ 1177 +A RPT ++ L + E++ Sbjct 1598 AKAHKRPTMTEVVQQLMLITEQFD 1621 Score = 58.5 bits (140), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 56/251 (22%), Positives = 100/251 (40%), Gaps = 22/251 (9%) Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 +G E+ V L D+ +F+E +M+ + H ++ + P +V E++ Sbjct 806 KGTEVAVKLISSKHVSKDMERSFFEEVKIMTSLRHPNVVLFMAASTKSPNMCIVMEFMSL 865 Query 693 GPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G L L E +P A K+ +A Q + + +L + +VH ++ N+LL + Sbjct 866 GSLYDLLGNELIPEIPYALKIKMAYQASKGMHFLHSSGIVHRDLKSLNLLL-------DS 918 Query 752 SPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 +K+SD G+ + + + I W+APE L D + FG L Sbjct 919 KWNVKVSDFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSFGIILW 978 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------CPQLATLTSQCLTYEPTQRPS 858 E+ E P + +P+ R P S + L QC + RP+ Sbjct 979 EL-LTREQPYKGMTPAAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQCWHSDTIIRPT 1037 Query 859 FRTILRDLTRL 869 F I+ L+ + Sbjct 1038 FLEIMTRLSNI 1048 Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 50/225 (22%), Positives = 93/225 (41%), Gaps = 26/225 (12%) Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 L F + +S++ H+++ G C++ P +VTEY+ G L L+ + A K+ Sbjct 1404 LEFRAEMAFLSELKHSNIVTFIGACIKKPNICIVTEYMRMGNLRDVLKNPDIKITFANKL 1463 Query 713 VVAQQLASALSYLENKN--LVHGNVCGRNILLAR-LGLAEGTSPFIKLSDPGVGLGALSR 769 + A + YL + N +VH ++ NIL+ + F ++ + + Sbjct 1464 KLLYGAAMGIDYLHSSNPMIVHRDIKPANILVDEHFNVKIADFGFARIKEDNTTM----- 1518 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 R W APE + G D + FG + E+ L + P + +F + Sbjct 1519 -TRCGTPCWTAPEVIRG--EKYCEKADVFSFGVVMWEV-------LTGKEPFAECNFMKV 1568 Query 830 QHRLPE------PS-CP-QLATLTSQCLTYEPTQRPSFRTILRDL 866 + E PS CP + A L +C + +RP+ +++ L Sbjct 1569 SLDILEGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTMTEVVQQL 1613 >sp|A7J1T0|M313B_XENLA Mitogen-activated protein kinase kinase kinase 13-B OS=Xenopus laevis OX=8355 GN=map3k13-b PE=2 SV=1 Length=961 Score = 103 bits (256), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 84/273 (31%), Positives = 123/273 (45%), Gaps = 39/273 (14%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI--LRTL 954 + +++ LG G G V L + GE VA+K ++ ++E DI LR L Sbjct 171 ISELQWLGSGAQGAVFLGKF------RGEEVAIKKVRE----------QKETDIKHLRKL 214 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAY 1013 H +II +KG C ++MEY G L + L +LL+ ++ I GM Y Sbjct 215 KHPNIIAFKGVCTQA--PCYCILMEYCAQGQLYEVLRAGRKVTPKLLVEWSTGIASGMNY 272 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 LH IHRDL + NVL+ + VKI DFG +K + + + V W APE + Sbjct 273 LHLHKIIHRDLKSPNVLVTHADTVKISDFGTSKELSD----KSTKMSFAGTVAWMAPEVI 328 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + D+WSFGV L+ELLT P K ++ I G + Sbjct 329 RNEPVSEKVDIWSFGVLLWELLT-----GEIPYKDVDSSAIIWG---------VGSNSLH 374 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 LP P CP LMK W+++ RP+F ++ Sbjct 375 LPVPSTCPDGFKILMKQTWQSKPRNRPSFRQIL 407 Score = 63.5 bits (153), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 77/308 (25%), Positives = 121/308 (39%), Gaps = 54/308 (18%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 +A L Q V +EI++L LG G + V+ G+ R Sbjct 149 GKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFR----------------- 191 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 G+E+ + KV + DI + ++ H ++ GVC + P ++ Sbjct 192 -------GEEV-AIKKVREQKETDIKH--------LRKLKHPNIIAFKGVCTQAPCYCIL 235 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLAR 744 EY G L LR R P K++V + +AS ++YL ++H ++ N+L+ Sbjct 236 MEYCAQGQLYEVLRAGRKVTP---KLLVEWSTGIASGMNYLHLHKIIHRDLKSPNVLVTH 292 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFG 801 +K+SD G + ++ + W+APE + +S +D W FG Sbjct 293 ADT-------VKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFG 343 Query 802 ATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPS 858 L E+ GE P + S LP PS CP L Q +P RPS Sbjct 344 VLLWEL-LTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPS 402 Query 859 FRTILRDL 866 FR IL L Sbjct 403 FRQILMHL 410 >sp|P27966|RMIL_AVEVR Serine/threonine-protein kinase-transforming protein Rmil OS=Avian rous-associated virus type 1 OX=11950 GN=V-RMIL PE=3 SV=1 Length=450 Score = 100 bits (250), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 79/277 (29%), Positives = 123/277 (44%), Gaps = 41/277 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK L PQ +K E+ +LR H +I+ Sbjct 89 IGSGSFGTV----YKGKWHGD---VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 141 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + L +V ++ SL +L + +L+ A+Q +GM YLHA+ Sbjct 142 FMGYST---KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSI 198 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPE---GHEYYRVREDGDSPVFWYAPECLK-- 1074 IHRDL + N+ L D VKIGDFGLA H++ E + W APE ++ Sbjct 199 IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQF----EQLSGSILWMAPEVIRMQ 254 Query 1075 -EYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 + + + SDV++FG+ LYEL+T + + + F+ G ++ +R Sbjct 255 DKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVR------ 308 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 CP + LM C + + RP F ++ Sbjct 309 --------SNCPKAMKRLMAECLKKKRDERPLFPQIL 337 Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 58/244 (24%), Positives = 103/244 (42%), Gaps = 24/244 (10%) Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +L V P+ + AF ++ + H ++ G + P+ +VT++ E L L Sbjct 110 MLNVTAPTPQQLQ-AFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHL 167 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 M + +A+Q A + YL K+++H ++ NI L +K+ D Sbjct 168 HIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE-------DLTVKIGD 220 Query 760 PGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGATLLEICFDGE 812 G+ G+ E+ I W+APE + N S D + FG L E+ G+ Sbjct 221 FGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYEL-MTGQ 279 Query 813 APLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQRPSFRTILRD 865 P + + ++ F R + P+ S CP+ + L ++CL + +RP F IL Sbjct 280 LPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILAS 339 Query 866 LTRL 869 + L Sbjct 340 IELL 343 >sp|G4NDR3|MCK1_PYRO7 Mitogen-activated protein kinase kinae kinase MCK1 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507 GN=MCK1 PE=1 SV=1 Length=1528 Score = 103 bits (257), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 86/297 (29%), Positives = 143/297 (48%), Gaps = 47/297 (16%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL----KADCGPQHR--- 941 PT F R+ K + +G+G +G+V L N TGE +AVK + +A G + R Sbjct 1233 PTTF--RWFKG-QLIGKGTYGRVYLGM----NATTGEFLAVKEVEVNPRAAAGDKKRMKE 1285 Query 942 --SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLA 998 + QEI+ ++ L H +I++Y GC ++ E S+ + +EY+ GS+ L ++ + Sbjct 1286 LVAALDQEIETMQHLDHVNIVQYLGC--ERKETSISIFLEYISGGSIGSCLRKNGKFEES 1343 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE--GHEYYR 1056 + +Q G+AYLH + +HRDL A N+LLD D KI DFG++K G++ Sbjct 1344 VVQSLTRQTLSGLAYLHREGILHRDLKADNILLDVDGTAKISDFGISKKTDNIYGNDKSN 1403 Query 1057 VREDGDSPVFWYAPECLKEYKFYYAS--DVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + VFW APE ++ Y++ D+WS G + E+ + + P K + I Sbjct 1404 SMQGS---VFWMAPEVIRSQGEGYSAKVDIWSLGCVVLEMF----AGRRPWAKEEAVGAI 1456 Query 1115 AQGQMTVLRLTELLERGERLPRPDK-----CPCEVYHLMKNCWETEASFRPTFENLI 1166 + + GE P P+ P V +M +C+ ++ RPT L+ Sbjct 1457 YK-----------IANGEIPPIPEDVQDTISPIAVAFMM-DCFTVDSHDRPTANKLL 1501 Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust. Identities = 43/172 (25%), Positives = 71/172 (41%), Gaps = 17/172 (10%) Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV-TEYVEHGPLDVWLRRERGHVPM 708 ++ A + M + H ++ G C R +I + EY+ G + LR+ G Sbjct 1285 ELVAALDQEIETMQHLDHVNIVQYLG-CERKETSISIFLEYISGGSIGSCLRKN-GKFEE 1342 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----- 763 + + +Q S L+YL + ++H ++ NILL G A K+SD G+ Sbjct 1343 SVVQSLTRQTLSGLAYLHREGILHRDLKADNILLDVDGTA-------KISDFGISKKTDN 1395 Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G + W+APE + S +D W G +LE+ F G P Sbjct 1396 IYGNDKSNSMQGSVFWMAPEVIRSQGEGYSAKVDIWSLGCVVLEM-FAGRRP 1446 >sp|O49840|PBL3_ARATH Probable serine/threonine-protein kinase PBL3 OS=Arabidopsis thaliana OX=3702 GN=PBL3 PE=1 SV=1 Length=426 Score = 100 bits (249), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 79/207 (38%), Positives = 109/207 (53%), Gaps = 20/207 (10%) Query 903 LGEGHFGKVSLYCYDPTN-----DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LGEG FG V D T G+G +VAVK LK + G Q W E++ L L H Sbjct 89 LGEGGFGYVFKGWIDGTTLTASKPGSGIVVAVKKLKTE-GYQGHKEWLTEVNYLGQLSHP 147 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI------CEGM 1011 +++K G C +GE L LV E++P GSL ++L R AQ L +A ++ +G+ Sbjct 148 NLVKLVGYCV-EGENRL-LVYEFMPKGSLENHLFRRG---AQPLTWAIRMKVAIGAAKGL 202 Query 1012 AYLH--AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 +LH I+RD A N+LLD + K+ DFGLAKA P G + + V + A Sbjct 203 TFLHDAKSQVIYRDFKAANILLDAEFNSKLSDFGLAKAGPTGDKTH-VSTQVMGTHGYAA 261 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096 PE + + SDV+SFGV L ELL+ Sbjct 262 PEYVATGRLTAKSDVYSFGVVLLELLS 288 Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 68/265 (26%), Positives = 111/265 (42%), Gaps = 38/265 (14%) Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 G + V +K L + + + + Q+SH +L + G CV G ++V E++ G Sbjct 113 GSGIVVAVKKLKTEGYQGHKEWLTEVNYLGQLSHPNLVKLVGYCVEGENRLLVYEFMPKG 172 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGLAE 749 L+ L R RG P+ W +M VA A L++L + +++ + NILL AE Sbjct 173 SLENHLFR-RGAQPLTWAIRMKVAIGAAKGLTFLHDAKSQVIYRDFKAANILLD----AE 227 Query 750 GTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 S KLSD G+ + ++ + + APE + G L+ D + FG Sbjct 228 FNS---KLSDFGLAKAGPTGDKTHVSTQVMGTHGYAAPEYVATG--RLTAKSDVYSFGVV 282 Query 804 LLEICFDGEAPLQSRSPSE--------------KEHFYQRQHRL----PEPSCPQLATLT 845 LLE+ A +S+ E ++ F RL P+ A+L Sbjct 283 LLELLSGRRAVDKSKVGMEQSLVDWATPYLGDKRKLFRIMDTRLGGQYPQKGAYTAASLA 342 Query 846 SQCLTYEPTQRPSFRTILRDLTRLQ 870 QCL + RP +L L +L+ Sbjct 343 LQCLNPDAKLRPKMSEVLAKLDQLE 367 >sp|Q06548|PBL9_ARATH Probable serine/threonine-protein kinase PBL9 OS=Arabidopsis thaliana OX=3702 GN=PBL9 PE=1 SV=1 Length=410 Score = 100 bits (248), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 92/290 (32%), Positives = 136/290 (47%), Gaps = 28/290 (10%) Query 903 LGEGHFGKV--------SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 LGEG FG V SL P GTG ++AVK L D G Q W E++ L Sbjct 74 LGEGGFGCVFKGWIDEKSLTASRP---GTGLVIAVKKLNQD-GWQGHQEWLAEVNYLGQF 129 Query 955 YHEHIIKYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQIC 1008 H H++K G C ED+ LV E++P GSL ++L R + L L A Sbjct 130 SHRHLVKLIGYCLEDEHR---LLVYEFMPRGSLENHLFRRGLYFQPLSWKLRLKVALGAA 186 Query 1009 EGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE-YYRVREDGDSPV 1065 +G+A+LH+ I+RD N+LLD++ K+ DFGLAK P G + + R G Sbjct 187 KGLAFLHSSETRVIYRDFKTSNILLDSEYNAKLSDFGLAKDGPIGDKSHVSTRVMGTHG- 245 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR- 1123 + APE L SDV+SFGV L ELL+ + ++ P+ L+ A+ + R Sbjct 246 -YAAPEYLATGHLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRK 304 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + +++ + + C+V L C TE RP ++ L+ + Sbjct 305 IFRVIDNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVVSHLEHIQ 354 Score = 60.5 bits (145), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 90/348 (26%), Positives = 144/348 (41%), Gaps = 66/348 (19%) Query 568 RASPRTL-------NLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618 R SPRT NL SF + + S LG+G V++G + Sbjct 38 RPSPRTEGEILQSPNLKSFSFAELKSATRNFRPDSVLGEGGFGCVFKGWI---------- 87 Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678 DE L R G L + +K L+ + + + Q SH HL + G C+ Sbjct 88 ----DEKSLTASRP-GTGLVIAVKKLNQDGWQGHQEWLAEVNYLGQFSHRHLVKLIGYCL 142 Query 679 RGPENIMVTEYVEHGPLDVWL-RRERGHVPMAWK--MVVAQQLASALSYLENKN--LVHG 733 ++V E++ G L+ L RR P++WK + VA A L++L + +++ Sbjct 143 EDEHRLLVYEFMPRGSLENHLFRRGLYFQPLSWKLRLKVALGAAKGLAFLHSSETRVIYR 202 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVE-RI----PWLAPECLPGG 787 + NILL + KLSD G+ G + + V R+ + APE L G Sbjct 203 DFKTSNILL-------DSEYNAKLSDFGLAKDGPIGDKSHVSTRVMGTHGYAAPEYLATG 255 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--------------------EHFY 827 L+T D + FG LLE+ A ++R E+ ++ Sbjct 256 --HLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRKIFRVIDNRL 313 Query 828 QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 Q Q+ + E +C ++ATL+ +CLT E RP+ ++ L +Q N A Sbjct 314 QDQYSM-EEAC-KVATLSLRCLTTEIKLRPNMSEVVSHLEHIQSLNAA 359 >sp|Q54TA3|MRKC_DICDI Probable serine/threonine-protein kinase MARK-C OS=Dictyostelium discoideum OX=44689 GN=mrkC PE=3 SV=1 Length=773 Score = 102 bits (254), Expect = 9e-21, Method: Compositional matrix adjust. Identities = 71/200 (36%), Positives = 107/200 (54%), Gaps = 14/200 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEH 958 + LG G FGKV L TN T E VA+K +K + G Q + ++ EIDI++ L H + Sbjct 50 KTLGNGTFGKVKL----GTNICTKENVAIKFIKNNKLSGKQKETCFR-EIDIMKLLDHPN 104 Query 959 IIKYKGCCEDQGEK-SLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHA 1016 I+K + + E+ + L++EYV G L DY+ R I + F +Q+ + Y HA Sbjct 105 IVKLLDVVDKREEEGTTYLIVEYVSGGELFDYIVAREYIKEKEARKFFRQMISAIEYCHA 164 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL N+LLD++ +KI DFGL+ + G ++ E + APE LK Sbjct 165 NLIVHRDLKPENLLLDSNGDIKISDFGLSNNIQPG----KLLESFCGSPLYAAPEILKAE 220 Query 1077 KFYY-ASDVWSFGVTLYELL 1095 K+ D+WS GV +Y +L Sbjct 221 KYLGPPVDIWSLGVIMYAVL 240 >sp|Q9C9U5|SIS8_ARATH Probable serine/threonine-protein kinase SIS8 OS=Arabidopsis thaliana OX=3702 GN=SIS8 PE=1 SV=1 Length=1030 Score = 102 bits (255), Expect = 9e-21, Method: Compositional matrix adjust. Identities = 81/283 (29%), Positives = 131/283 (46%), Gaps = 34/283 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G +G+V D G VAVK L D + ++ E+ I++ L H +I+ Sbjct 754 IGLGSYGEVY------RGDWHGTEVAVKKFLDQDLTGEALEEFRSEVRIMKKLRHPNIVL 807 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018 + G +L +V E++P GSL + P + + + L A GM YLH+ + Sbjct 808 FMGAV--TRPPNLSIVTEFLPRGSLYRLIHRPNNQLDERRRLRMALDAARGMNYLHSCNP 865 Query 1019 -YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL + N+L+D + +VK+ DFGL++ H Y + W APE L+ Sbjct 866 MIVHRDLKSPNLLVDKNWVVKVCDFGLSRM---KHSTYLSSKSTAGTAEWMAPEVLRNEP 922 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKF--LELIGIAQGQMTVLRLTELLERGERLP 1135 DV+S+GV L+EL T Q P K ++++G Q RL Sbjct 923 ADEKCDVYSYGVILWELFTL----QQPWGKMNPMQVVGAVGFQH------------RRLD 966 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 PD + L+ CW+T++ RP+F ++ LK + + G Sbjct 967 IPDFVDPAIADLISKCWQTDSKLRPSFAEIMASLKRLQKPVTG 1009 Score = 60.8 bits (146), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 62/242 (26%), Positives = 102/242 (42%), Gaps = 20/242 (8%) Query 639 VVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V K LD AL F +M ++ H ++ G R P +VTE++ G L Sbjct 773 AVKKFLDQDLTGEALEEFRSEVRIMKKLRHPNIVLFMGAVTRPPNLSIVTEFLPRGSLYR 832 Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFI 755 + R + ++ +A A ++YL + N +VH ++ N+L+ + + + Sbjct 833 LIHRPNNQLDERRRLRMALDAARGMNYLHSCNPMIVHRDLKSPNLLVDK-------NWVV 885 Query 756 KLSDPGVGLGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 K+ D G+ LS + W+APE L D + +G L E+ F Sbjct 886 KVCDFGLSRMKHSTYLSSKSTAGTAEWMAPEVLRN--EPADEKCDVYSYGVILWEL-FTL 942 Query 812 EAPLQSRSPSEKEHFYQRQHR---LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + P +P + QHR +P+ P +A L S+C + RPSF I+ L R Sbjct 943 QQPWGKMNPMQVVGAVGFQHRRLDIPDFVDPAIADLISKCWQTDSKLRPSFAEIMASLKR 1002 Query 869 LQ 870 LQ Sbjct 1003 LQ 1004 >sp|F4J0D2|PBL36_ARATH Serine/threonine-protein kinase PBL36 OS=Arabidopsis thaliana OX=3702 GN=PBL36 PE=1 SV=2 Length=476 Score = 100 bits (250), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 75/205 (37%), Positives = 104/205 (51%), Gaps = 16/205 (8%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LGEG FG V + P GTG VAVK L D G Q W EI+ L L H Sbjct 132 LGEGGFGCVFKGWIEENGTAPVKPGTGLTVAVKTLNPD-GLQGHKEWLAEINFLGNLVHP 190 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLH 1015 ++K G C ++ ++ LV E++P GSL ++L R ++ L + + A +G+A+LH Sbjct 191 SLVKLVGYCMEEDQR--LLVYEFMPRGSLENHLFRRTLPLPWSVRMKIALGAAKGLAFLH 248 Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPE 1071 + I+RD N+LLD + K+ DFGLAK P E + R G + APE Sbjct 249 EEAEKPVIYRDFKTSNILLDGEYNAKLSDFGLAKDAPDEKKSHVSTRVMGT--YGYAAPE 306 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 + SDV+SFGV L E+LT Sbjct 307 YVMTGHLTTKSDVYSFGVVLLEILT 331 Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 78/313 (25%), Positives = 127/313 (41%), Gaps = 57/313 (18%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 S LG+G V++G + G+ P+ PG L V +K L+P Sbjct 130 SLLGEGGFGCVFKGWIEENGTA-----------PVKPGTG----LTVAVKTLNPDGLQGH 174 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 + + + + H L + G C+ + ++V E++ G L+ L R +P + +M Sbjct 175 KEWLAEINFLGNLVHPSLVKLVGYCMEEDQRLLVYEFMPRGSLENHLFRRTLPLPWSVRM 234 Query 713 VVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 +A A L++L K +++ + NILL A KLSD GL + Sbjct 235 KIALGAAKGLAFLHEEAEKPVIYRDFKTSNILLDGEYNA-------KLSD--FGLAKDAP 285 Query 770 EERVERIP--------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 +E+ + + APE + G L+T D + FG LLEI + +SR Sbjct 286 DEKKSHVSTRVMGTYGYAAPEYVMTG--HLTTKSDVYSFGVVLLEILTGRRSVDKSRPNG 343 Query 822 EKE-------HFY--QRQHRLPEPSC--------PQLAT-LTSQCLTYEPTQRPSFRTIL 863 E+ H +R +RL +P Q AT + +QCL + RP ++ Sbjct 344 EQNLVEWVRPHLLDKKRFYRLLDPRLEGHYSIKGAQKATQVAAQCLNRDSKARPKMSEVV 403 Query 864 RDLTRLQPHNLAD 876 L L NL D Sbjct 404 EALKPLP--NLKD 414 >sp|Q9LPQ3|M2K7_ARATH Mitogen-activated protein kinase kinase 7 OS=Arabidopsis thaliana OX=3702 GN=MKK7 PE=1 SV=1 Length=307 Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 62/204 (30%), Positives = 104/204 (51%), Gaps = 13/204 (6%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 ++K+ LG G G V Y + TGE+ A+K++ D P +E++ILR Sbjct 45 VEKLHVLGRGSSGIV----YKVHHKTTGEIYALKSVNGDMSPAFTRQLAREMEILRRTDS 100 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016 ++++ +G E + ++MEY+ G+L R ++ QL F++QI +G++YLH+ Sbjct 101 PYVVRCQGIFEKPIVGEVSILMEYMDGGNLESL--RGAVTEKQLAGFSRQILKGLSYLHS 158 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE----C 1072 +HRD+ N+LL++ VKI DFG++K + +Y + +PE Sbjct 159 LKIVHRDIKPANLLLNSRNEVKIADFGVSKIITRSLDYC---NSYVGTCAYMSPERFDSA 215 Query 1073 LKEYKFYYASDVWSFGVTLYELLT 1096 E YA D+WSFGV + EL Sbjct 216 AGENSDVYAGDIWSFGVMILELFV 239 Score = 42.0 bits (97), Expect = 0.023, Method: Compositional matrix adjust. Identities = 47/186 (25%), Positives = 75/186 (40%), Gaps = 28/186 (15%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL-- 742 ++ EY++ G L+ RG V ++Q+ LSYL + +VH ++ N+LL Sbjct 120 ILMEYMDGGNLESL----RGAVTEKQLAGFSRQILKGLSYLHSLKIVHRDIKPANLLLNS 175 Query 743 ------ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMD 796 A G+++ + + + VG A ER + G NS A D Sbjct 176 RNEVKIADFGVSKIITRSLDYCNSYVGTCAYMSPERFDS---------AAGENSDVYAGD 226 Query 797 KWGFGATLLEICFDGEAPL--QSRSPSEKEHF----YQRQHRLPEPSCPQLATLTSQCLT 850 W FG +LE+ F G PL Q + P + R PE + + CL Sbjct 227 IWSFGVMILEL-FVGHFPLLPQGQRPDWATLMCVVCFGEPPRAPEGCSDEFRSFVDCCLR 285 Query 851 YEPTQR 856 E ++R Sbjct 286 KESSER 291 >sp|Q63796|M3K12_RAT Mitogen-activated protein kinase kinase kinase 12 OS=Rattus norvegicus OX=10116 GN=Map3k12 PE=1 SV=1 Length=888 Score = 102 bits (254), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 79/262 (30%), Positives = 115/262 (44%), Gaps = 37/262 (14%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 GE VAVK + R + +I LR L H +II +KG C ++ME+ Sbjct 179 GEEVAVKKV--------RDLKETDIKHLRKLKHPNIITFKGVCTQA--PCYCILMEFCAQ 228 Query 984 GSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 G L + L + + L+ ++ I GM YLH IHRDL + N+L+ D +VKI DF Sbjct 229 GQLYEVLRAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDF 288 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 G +K + + + V W APE ++ D+WSFGV L+ELLT Sbjct 289 GTSKELSD----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG----- 339 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 P K ++ I G + LP P CP L++ CW + RP+F Sbjct 340 EIPYKDVDSSAIIWG---------VGSNSLHLPVPSSCPDGFKILLRQCWNRKPRNRPSF 390 Query 1163 ENLI--------PILKTVHEKY 1176 ++ +L T E Y Sbjct 391 RQILLHLDIASADVLSTPQETY 412 Score = 63.9 bits (154), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 71/260 (27%), Positives = 106/260 (41%), Gaps = 36/260 (14%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 GR G+E+ V KV D DI + ++ H ++ GVC + P ++ E+ Sbjct 175 GRFHGEEV-AVKKVRDLKETDI--------KHLRKLKHPNIITFKGVCTQAPCYCILMEF 225 Query 690 VEHGPLDVWLRRERGHVP---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 G L LR R P + W M +A ++YL ++H ++ N+L+ Sbjct 226 CAQGQLYEVLRAGRPVTPSLLVDWSMGIA----GGMNYLHLHKIIHRDLKSPNMLIT--- 278 Query 747 LAEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +K+SD G + ++ + W+APE + +S +D W FG Sbjct 279 ----YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 332 Query 804 LLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFR 860 L E+ GE P + S LP PS CP L QC +P RPSFR Sbjct 333 LWEL-LTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNRKPRNRPSFR 391 Query 861 TILRDLTRLQPHNLADVLTV 880 IL L ADVL+ Sbjct 392 QILLHLDIAS----ADVLST 407 >sp|O48814|BIK1_ARATH Serine/threonine-protein kinase BIK1 OS=Arabidopsis thaliana OX=3702 GN=BIK1 PE=1 SV=1 Length=395 Score = 99.4 bits (246), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 92/290 (32%), Positives = 136/290 (47%), Gaps = 24/290 (8%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +GEG FG V D PT GTG ++AVK L + HR W EI+ L L H Sbjct 73 IGEGGFGCVFKGWLDESTLTPTKPGTGLVIAVKKLNQEGFQGHRE-WLTEINYLGQLSHP 131 Query 958 HIIKYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLF-----AQQICEGM 1011 +++K G C ED+ LV E++ GSL ++L R L F A +G+ Sbjct 132 NLVKLIGYCLEDEHR---LLVYEFMQKGSLENHLFRRGAYFKPLPWFLRVNVALDAAKGL 188 Query 1012 AYLHAQ--HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH-EYYRVREDGDSPVFWY 1068 A+LH+ I+RD+ A N+LLD D K+ DFGLA+ P G Y R G + Sbjct 189 AFLHSDPVKVIYRDIKASNILLDADYNAKLSDFGLARDGPMGDLSYVSTRVMGTYG--YA 246 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + SDV+SFGV L E+L+ + + P K L+ A+ +T R L Sbjct 247 APEYMSSGHLNARSDVYSFGVLLLEILSGKRALDHNRPAKEENLVDWARPYLTSKRKVLL 306 Query 1128 L--ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 + R + P++ + + C E RPT + ++ L+ + + Sbjct 307 IVDNRLDTQYLPEEA-VRMASVAVQCLSFEPKSRPTMDQVVRALQQLQDN 355 Score = 70.1 bits (170), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 76/291 (26%), Positives = 128/291 (44%), Gaps = 44/291 (15%) Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 DE L P + G L + +K L+ + + + Q+SH +L + G C+ Sbjct 87 DESTLTPTKP-GTGLVIAVKKLNQEGFQGHREWLTEINYLGQLSHPNLVKLIGYCLEDEH 145 Query 683 NIMVTEYVEHGPLDVWLRRERGHV-PMAW--KMVVAQQLASALSYLENK--NLVHGNVCG 737 ++V E+++ G L+ L R + P+ W ++ VA A L++L + +++ ++ Sbjct 146 RLLVYEFMQKGSLENHLFRRGAYFKPLPWFLRVNVALDAAKGLAFLHSDPVKVIYRDIKA 205 Query 738 RNILLARLGLAEGTSPFIKLSDPGVG----LGALS--REERVERIPWLAPECLPGGANSL 791 NILL KLSD G+ +G LS + + APE + G L Sbjct 206 SNILL-------DADYNAKLSDFGLARDGPMGDLSYVSTRVMGTYGYAAPEYMSSG--HL 256 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF------YQRQHR------------- 832 + D + FG LLEI G+ L P+++E+ Y R Sbjct 257 NARSDVYSFGVLLLEI-LSGKRALDHNRPAKEENLVDWARPYLTSKRKVLLIVDNRLDTQ 315 Query 833 -LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 LPE + ++A++ QCL++EP RP+ ++R L +LQ NL NP Sbjct 316 YLPEEAV-RMASVAVQCLSFEPKSRPTMDQVVRALQQLQ-DNLGKPSQTNP 364 >sp|Q8IWU2|LMTK2_HUMAN Serine/threonine-protein kinase LMTK2 OS=Homo sapiens OX=9606 GN=LMTK2 PE=1 SV=2 Length=1503 Score = 102 bits (255), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 90/286 (31%), Positives = 135/286 (47%), Gaps = 55/286 (19%) Query 894 KRYLKKIRDLGEGHFGKVSL-YCYDPTNDGTGEMVA---VKALKADCGPQHRSGWKQEID 949 + L I+++G G FGKV L Y TG VA VK LKA P+ + + + + Sbjct 134 RHSLNYIQEIGNGWFGKVLLGEIY------TGTSVARVIVKELKASANPKEQDTFLKNGE 187 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQ 1006 L H +I++ G C + LV E+ LG L+ YL H G +Q +L + Sbjct 188 PYYILQHPNILQCVGQCVEA--IPYLLVFEFCDLGDLKAYLRSEQEHMRGDSQTMLLQRM 245 Query 1007 ICE---GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED--- 1060 CE G+A +H H++H DLA RN L +D VK+GD+G+ + R +ED Sbjct 246 ACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVKVGDYGIG--------FSRYKEDYIE 297 Query 1061 -GDSPVF---WYAPECLKEYKF-------YYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 D VF W APE + ++ S++WS GVTL+EL D++ P + Sbjct 298 TDDKKVFPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVTLWELF---DNAAQPYSNLS 354 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPD-KCPCEV--YHLMKNCW 1152 L + Q V+R ER +LP+P + P Y +++ CW Sbjct 355 NLDVLNQ----VIR-----ERDTKLPKPQLEQPYSDRWYEVLQFCW 391 Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 62/267 (23%), Positives = 116/267 (43%), Gaps = 37/267 (14%) Query 638 RVVLKVL----DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 RV++K L +P D L E ++ H ++ G CV ++V E+ + G Sbjct 164 RVIVKELKASANPKEQDTFLKNGEPYYILQ---HPNILQCVGQCVEAIPYLLVFEFCDLG 220 Query 694 PLDVWLRRERGHVPMAWKMVVAQ----QLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 L +LR E+ H+ + ++ Q ++A+ L+ + + +H ++ RN L Sbjct 221 DLKAYLRSEQEHMRGDSQTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLT------ 274 Query 750 GTSPFIKLSDPGVGLGAL------SREERVERIPWLAPECLPGGANSLSTA-----MDKW 798 + +K+ D G+G + +++V + W APE + + L TA + W Sbjct 275 -SDLNVKVGDYGIGFSRYKEDYIETDDKKVFPLRWTAPELVTSFQDRLLTADQTKYSNIW 333 Query 799 GFGATLLEICFDGEAPLQSRSPSE--KEHFYQRQHRLPEPSCPQ-LATLTSQCLTY---E 852 G TL E+ + P + S + + +R +LP+P Q + + L + Sbjct 334 SLGVTLWELFDNAAQPYSNLSNLDVLNQVIRERDTKLPKPQLEQPYSDRWYEVLQFCWLS 393 Query 853 PTQRPSFRTILRDLT--RLQPHNLADV 877 P +RP+ + R LT RLQ ++V Sbjct 394 PEKRPAAEDVHRLLTYLRLQSQRDSEV 420 >sp|O81472|MP3K2_ARATH Mitogen-activated protein kinase kinase kinase 9 OS=Arabidopsis thaliana OX=3702 GN=MEKK2 PE=1 SV=1 Length=773 Score = 102 bits (253), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 80/271 (30%), Positives = 134/271 (49%), Gaps = 34/271 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQ---EIDILRTLYHEH 958 L +G FG V Y+ ++ G+ AVK + D G Q + +Q EI +L L H++ Sbjct 507 LRQGSFGSV----YEAISED-GDFFAVKEVSLLDQGSQAQECIQQLEGEIALLSQLEHQN 561 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I++Y+G D+ +L + +E V GSL + R+ I + + L+ +QI +G+ YLH + Sbjct 562 ILRYRGT--DKDGSNLYIFLELVTQGSLLELYRRYQIRDSLISLYTKQILDGLKYLHHKG 619 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL--KEY 1076 +IHRD+ +L+D + VK+ DFGLAK V + ++ +E +FW APE + K+ Sbjct 620 FIHRDIKCATILVDANGTVKLADFGLAK-VSKLNDIKSRKE----TLFWMAPEVINRKDN 674 Query 1077 KFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 Y + +D+WS G T+ E+ T Q P + + + + + RG Sbjct 675 DGYRSPADIWSLGCTVLEMCT----GQIPYSDLEPVEALFR-----------IRRGTLPE 719 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 PD + H + C + RPT L+ Sbjct 720 VPDTLSLDARHFILKCLKLNPEERPTATELL 750 Score = 62.8 bits (151), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 60/214 (28%), Positives = 95/214 (44%), Gaps = 25/214 (12%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 +L+SQ+ H ++ G G + E V G L RR + + + +Q+ Sbjct 552 ALLSQLEHQNILRYRGTDKDGSNLYIFLELVTQGSLLELYRRY--QIRDSLISLYTKQIL 609 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR----EERVER 775 L YL +K +H ++ IL+ A GT +KL+D GL +S+ + R E Sbjct 610 DGLKYLHHKGFIHRDIKCATILVD----ANGT---VKLAD--FGLAKVSKLNDIKSRKET 660 Query 776 IPWLAPECLPGGANS-LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834 + W+APE + N + D W G T+LE+C G+ P P E F R+ LP Sbjct 661 LFWMAPEVINRKDNDGYRSPADIWSLGCTVLEMCT-GQIPYSDLEPVEA-LFRIRRGTLP 718 Query 835 EPSCPQLATLTS-----QCLTYEPTQRPSFRTIL 863 E P +L + +CL P +RP+ +L Sbjct 719 E--VPDTLSLDARHFILKCLKLNPEERPTATELL 750 >sp|Q9UL54|TAOK2_HUMAN Serine/threonine-protein kinase TAO2 OS=Homo sapiens OX=9606 GN=TAOK2 PE=1 SV=2 Length=1235 Score = 102 bits (254), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 80/242 (33%), Positives = 121/242 (50%), Gaps = 32/242 (13%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDI 950 ++ +R++G G FG V + D N E+VA+K + + G Q W+ +E+ Sbjct 25 EKLFSDLREIGHGSFGAV-YFARDVRNS---EVVAIKKM-SYSGKQSNEKWQDIIKEVRF 79 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQIC 1008 L+ L H + I+Y+GC E + LVMEY LGS D L H L ++ + A Sbjct 80 LQKLRHPNTIQYRGCYLR--EHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAVTHGAL 136 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +G+AYLH+ + IHRD+ A N+LL LVK+GDFG A + + + +P +W Sbjct 137 QGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSFV------GTP-YWM 189 Query 1069 APE---CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP----TKFLELIGIAQGQMTV 1121 APE + E ++ DVWS G+T EL + + PP L IAQ + V Sbjct 190 APEVILAMDEGQYDGKVDVWSLGITCIEL-----AERKPPLFNMNAMSALYHIAQNESPV 244 Query 1122 LR 1123 L+ Sbjct 245 LQ 246 Score = 38.9 bits (89), Expect = 0.39, Method: Compositional matrix adjust. Identities = 44/186 (24%), Positives = 68/186 (37%), Gaps = 14/186 (8%) Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780 L+YL + N++H +V NILL+ GL +KL D G V W+A Sbjct 138 GLAYLHSHNMIHRDVKAGNILLSEPGL-------VKLGDFGSASIMAPANSFVGTPYWMA 190 Query 781 PEC-LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-- 837 PE L +D W G T +E+ + S H Q + + + Sbjct 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHW 250 Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRD---LTRLQPHNLADVLTVNPDSPASDPTVFHK 894 CL P RP+ +L+ L P + D++ D+ + Sbjct 251 SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA-VRELDNLQY 309 Query 895 RYLKKI 900 R +KKI Sbjct 310 RKMKKI 315 >sp|Q56UN5|M3K19_HUMAN Mitogen-activated protein kinase kinase kinase 19 OS=Homo sapiens OX=9606 GN=MAP3K19 PE=2 SV=1 Length=1328 Score = 102 bits (254), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 63/205 (31%), Positives = 109/205 (53%), Gaps = 20/205 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-----CGPQHRSGWKQEIDILRTLYHE 957 LG+G +G V YC + G+++AVK + D + ++E+D+L+ L H Sbjct 1067 LGKGAYGTV--YCGLTSQ---GQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHV 1121 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--FAQQICEGMAYLH 1015 +I+ Y G C E ++ + ME+VP GS+ + R L +++ + +QI +G+AYLH Sbjct 1122 NIVAYLGTC--LQENTVSIFMEFVPGGSISSIINRFG-PLPEMVFCKYTKQILQGVAYLH 1178 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP----EGHEYYRVREDGDSPVFWYAPE 1071 +HRD+ NV+L ++K+ DFG A+ + G ++ +P +W APE Sbjct 1179 ENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTP-YWMAPE 1237 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 + E + SD+WS G T++E+ T Sbjct 1238 VINESGYGRKSDIWSIGCTVFEMAT 1262 Score = 53.9 bits (128), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 63/251 (25%), Positives = 101/251 (40%), Gaps = 31/251 (12%) Query 633 RGQELRVVLKVLDPSHHDIALAFY----ETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 +GQ + V LD S+ A Y E L+ + H ++ G C++ + E Sbjct 1082 QGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFME 1141 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 +V G + + R G +P +Q+ ++YL +VH ++ G N++L G+ Sbjct 1142 FVPGGSISSIINR-FGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGI- 1199 Query 749 EGTSPFIKLSDPG-------VGLGALSRE--ERVERIP-WLAPECLPGGANSLSTAMDKW 798 IKL D G GL + + + P W+APE + + D W Sbjct 1200 ------IKLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVI--NESGYGRKSDIW 1251 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-----LPEPSCPQLATLTSQCLTYEP 853 G T+ E+ G+ PL S FY HR LP+ A CLT + Sbjct 1252 SIGCTVFEMA-TGKPPLASMD-RMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQ 1309 Query 854 TQRPSFRTILR 864 +RPS +L+ Sbjct 1310 HERPSALQLLK 1320 >sp|P11345|RAF1_RAT RAF proto-oncogene serine/threonine-protein kinase OS=Rattus norvegicus OX=10116 GN=Raf1 PE=1 SV=1 Length=648 Score = 101 bits (251), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 69/200 (35%), Positives = 102/200 (51%), Gaps = 17/200 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+ Sbjct 355 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILL 407 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ Sbjct 408 FMGY---MTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 464 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076 IHRD+ + N+ L VKIGDFGLA +V + S V W APE ++ Sbjct 465 IHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-VLWMAPEVIRMQDNN 523 Query 1077 KFYYASDVWSFGVTLYELLT 1096 F + SDV+S+G+ LYEL+T Sbjct 524 PFSFQSDVYSYGIVLYELMT 543 Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 70/286 (24%), Positives = 128/286 (45%), Gaps = 32/286 (11%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688 G+ G +LKV+DP+ + AF +++ + H ++ G + +N+ +VT+ Sbjct 366 GKWHGDVAVKILKVVDPTPEQLQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 422 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + E L L + M + +A+Q A + YL KN++H ++ NI L Sbjct 423 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF-----LH 477 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANS-LSTAMDKWGFG 801 EG + +K+ D G+ G+ E+ + W+APE + N+ S D + +G Sbjct 478 EGLT--VKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYG 535 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854 L E+ GE P + ++ F R + P+ S CP+ + L + C+ Sbjct 536 IVLYEL-MTGELPYSHINNRDQIIFMVGRGYASPDLSRLYKNCPKAMKRLVADCVKKVKE 594 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 +RP F IL + LQ H+L + + AS+P++ + + I Sbjct 595 ERPLFPQILSSIELLQ-HSLPKI-----NRSASEPSLHRAAHTEDI 634 >sp|Q869T7|PAKF_DICDI Serine/threonine-protein kinase pakF OS=Dictyostelium discoideum OX=44689 GN=pakF PE=3 SV=1 Length=1176 Score = 102 bits (254), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 59/194 (30%), Positives = 105/194 (54%), Gaps = 13/194 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G +G V Y T+ G +A+K + + + EI+IL+ +I+ Y Sbjct 400 LGDGAYGSV----YKGTHKDLGFTLAIKVI--EMKESESVSLQNEINILKNCKSPNIVSY 453 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G Q E + +++++ LGS+RD + ++ AQ+ + +G+ YLH+Q+ I Sbjct 454 FGSL--QTESHIWILLDFCALGSIRDIIESTEKTLNEAQISFVVKNTLKGLIYLHSQNII 511 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ A NVLL VKI DFG+++ + + + +E +P+ W APE + + + Y Sbjct 512 HRDVKAANVLLSEGCDVKIADFGVSEKLNGALD--QSKEMIGTPL-WMAPEVILKKNYDY 568 Query 1081 ASDVWSFGVTLYEL 1094 +D+WS G+T+ E+ Sbjct 569 KADIWSLGITIIEM 582 Score = 42.0 bits (97), Expect = 0.043, Method: Compositional matrix adjust. Identities = 41/153 (27%), Positives = 66/153 (43%), Gaps = 18/153 (12%) Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSRE 770 V + L YL ++N++H +V N+L L+EG +K++D GV GAL + Sbjct 494 VVKNTLKGLIYLHSQNIIHRDVKAANVL-----LSEGCD--VKIADFGVSEKLNGALDQS 546 Query 771 ERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 + + P W+APE + + D W G T++E+ DG P P Sbjct 547 KEMIGTPLWMAPEVI--LKKNYDYKADIWSLGITIIEMA-DGLPPHIDLPPMRAMKMVPN 603 Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPS 858 P+ P L ++CL +P +R S Sbjct 604 WPPPTFAEPKKWSPLLNDFLARCLVKDPEKRAS 636 >sp|P05625|RAF1_CHICK RAF proto-oncogene serine/threonine-protein kinase OS=Gallus gallus OX=9031 GN=RAF1 PE=2 SV=1 Length=647 Score = 101 bits (251), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 68/200 (34%), Positives = 102/200 (51%), Gaps = 17/200 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+ Sbjct 355 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILL 407 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ Sbjct 408 FMGY---MTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 464 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076 IHRD+ + N+ L VKIGDFGLA +V + S + W APE ++ Sbjct 465 IHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-ILWMAPEVIRMQDSN 523 Query 1077 KFYYASDVWSFGVTLYELLT 1096 F + SDV+S+G+ LYEL+T Sbjct 524 PFSFQSDVYSYGIVLYELMT 543 Score = 65.1 bits (157), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 72/286 (25%), Positives = 127/286 (44%), Gaps = 32/286 (11%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688 G+ G +LKV+DP+ AF +++ + H ++ G + +N+ +VT+ Sbjct 366 GKWHGDVAVKILKVVDPTPEQFQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 422 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + E L L + M + +A+Q A + YL KN++H ++ NI L Sbjct 423 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF-----LH 477 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFG 801 EG + +K+ D G+ G+ E+ I W+APE + +N S D + +G Sbjct 478 EGLT--VKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYG 535 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854 L E+ GE P + ++ F R + P+ S CP+ + L + CL Sbjct 536 IVLYEL-MTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCLKKVRE 594 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 +RP F IL + LQ H+L + + AS+P++ + + I Sbjct 595 ERPLFPQILSSIELLQ-HSLPKI-----NRSASEPSLHRASHTEDI 634 >sp|Q6ZQ29|TAOK2_MOUSE Serine/threonine-protein kinase TAO2 OS=Mus musculus OX=10090 GN=Taok2 PE=1 SV=3 Length=1240 Score = 102 bits (253), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 72/209 (34%), Positives = 109/209 (52%), Gaps = 23/209 (11%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDI 950 ++ +R++G G FG V + D N E+VA+K + + G Q W+ +E+ Sbjct 25 EKLFSDLREIGHGSFGAV-YFARDVRNS---EVVAIKKM-SYSGKQSNEKWQDIIKEVRF 79 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQIC 1008 L+ L H + I+Y+GC E + LVMEY LGS D L H L ++ + A Sbjct 80 LQKLRHPNTIQYRGCYLR--EHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAVTHGAL 136 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +G+AYLH+ + IHRD+ A N+LL LVK+GDFG A + + + +P +W Sbjct 137 QGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSFV------GTP-YWM 189 Query 1069 APE---CLKEYKFYYASDVWSFGVTLYEL 1094 APE + E ++ DVWS G+T EL Sbjct 190 APEVILAMDEGQYDGKVDVWSLGITCIEL 218 Score = 37.7 bits (86), Expect = 0.81, Method: Compositional matrix adjust. Identities = 44/186 (24%), Positives = 67/186 (36%), Gaps = 14/186 (8%) Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780 L+YL + N++H +V NILL+ GL +KL D G V W+A Sbjct 138 GLAYLHSHNMIHRDVKAGNILLSEPGL-------VKLGDFGSASIMAPANSFVGTPYWMA 190 Query 781 PEC-LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-- 837 PE L +D W G T +E+ + S H Q + + Sbjct 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPALQSGHW 250 Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRD---LTRLQPHNLADVLTVNPDSPASDPTVFHK 894 CL P RP+ +L+ L P + D++ D+ + Sbjct 251 SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA-VRELDNLQY 309 Query 895 RYLKKI 900 R +KKI Sbjct 310 RKMKKI 315 >sp|Q5R5M7|RAF1_PONAB RAF proto-oncogene serine/threonine-protein kinase OS=Pongo abelii OX=9601 GN=RAF1 PE=2 SV=1 Length=648 Score = 100 bits (250), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 69/200 (35%), Positives = 102/200 (51%), Gaps = 17/200 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+ Sbjct 355 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILL 407 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ Sbjct 408 FMGY---MTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 464 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076 IHRD+ + N+ L VKIGDFGLA +V + S V W APE ++ Sbjct 465 IHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-VLWMAPEVIRMQDNN 523 Query 1077 KFYYASDVWSFGVTLYELLT 1096 F + SDV+S+G+ LYEL+T Sbjct 524 PFSFQSDVYSYGIVLYELMT 543 Score = 63.5 bits (153), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 70/286 (24%), Positives = 127/286 (44%), Gaps = 32/286 (11%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688 G+ G +LKV+DP+ AF +++ + H ++ G + +N+ +VT+ Sbjct 366 GKWHGDVAVKILKVVDPTPEQFQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 422 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + E L L + M + +A+Q A + YL KN++H ++ NI L Sbjct 423 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF-----LH 477 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANS-LSTAMDKWGFG 801 EG + +K+ D G+ G+ E+ + W+APE + N+ S D + +G Sbjct 478 EGLT--VKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYG 535 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854 L E+ GE P + ++ F R + P+ S CP+ + L + C+ Sbjct 536 IVLYEL-MTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKE 594 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 +RP F IL + LQ H+L + + AS+P++ + + I Sbjct 595 ERPLFPQILSSIELLQ-HSLPKI-----NRSASEPSLHRAAHTEDI 634 >sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens OX=9606 GN=RAF1 PE=1 SV=1 Length=648 Score = 100 bits (250), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 69/200 (35%), Positives = 102/200 (51%), Gaps = 17/200 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+ Sbjct 355 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILL 407 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ Sbjct 408 FMGY---MTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 464 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076 IHRD+ + N+ L VKIGDFGLA +V + S V W APE ++ Sbjct 465 IHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-VLWMAPEVIRMQDNN 523 Query 1077 KFYYASDVWSFGVTLYELLT 1096 F + SDV+S+G+ LYEL+T Sbjct 524 PFSFQSDVYSYGIVLYELMT 543 Score = 63.5 bits (153), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 70/286 (24%), Positives = 127/286 (44%), Gaps = 32/286 (11%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688 G+ G +LKV+DP+ AF +++ + H ++ G + +N+ +VT+ Sbjct 366 GKWHGDVAVKILKVVDPTPEQFQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 422 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + E L L + M + +A+Q A + YL KN++H ++ NI L Sbjct 423 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF-----LH 477 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANS-LSTAMDKWGFG 801 EG + +K+ D G+ G+ E+ + W+APE + N+ S D + +G Sbjct 478 EGLT--VKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYG 535 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854 L E+ GE P + ++ F R + P+ S CP+ + L + C+ Sbjct 536 IVLYEL-MTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKE 594 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 +RP F IL + LQ H+L + + AS+P++ + + I Sbjct 595 ERPLFPQILSSIELLQ-HSLPKI-----NRSASEPSLHRAAHTEDI 634 >sp|Q9C5H5|M3K5G_ARATH Mitogen-activated protein kinase kinase kinase 5 OS=Arabidopsis thaliana OX=3702 GN=MAPKKK5 PE=1 SV=1 Length=716 Score = 101 bits (251), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 82/286 (29%), Positives = 134/286 (47%), Gaps = 47/286 (16%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK--------ADCGPQHRSGWKQEID 949 KK + +G G FG V Y +N TG + A+K ++ A+C Q +QEI Sbjct 347 KKGKLIGRGTFGSV----YVASNSETGALCAMKEVELFPDDPKSAECIKQ----LEQEIK 398 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--FAQQI 1007 +L L H +I++Y G + E + +EYV GS+ Y+ H + + ++ F + I Sbjct 399 LLSNLQHPNIVQYFGS--ETVEDRFFIYLEYVHPGSINKYIRDHCGTMTESVVRNFTRHI 456 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 G+AYLH + +HRD+ N+L+D +VK+ DFG+AK + ++ SP +W Sbjct 457 LSGLAYLHNKKTVHRDIKGANLLVDASGVVKLADFGMAKHLTGQRADLSLK---GSP-YW 512 Query 1068 YAPECLKEY-------KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 APE ++ +A D+WS G T+ E+ T PP + E G A Sbjct 513 MAPELMQAVMQKDSNPDLAFAVDIWSLGCTIIEMFTG-----KPP--WSEFEGAA-AMFK 564 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 V+R + P P+ E ++ C++ + RPT L+ Sbjct 565 VMR--------DSPPIPESMSPEGKDFLRLCFQRNPAERPTASMLL 602 Score = 57.4 bits (137), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 17/228 (7%) Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 DP + + L+S + H ++ G + EYV G ++ ++R G Sbjct 383 DPKSAECIKQLEQEIKLLSNLQHPNIVQYFGSETVEDRFFIYLEYVHPGSINKYIRDHCG 442 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763 + + + + S L+YL NK VH ++ G N+L+ G+ +KL+D G+ Sbjct 443 TMTESVVRNFTRHILSGLAYLHNKKTVHRDIKGANLLVDASGV-------VKLADFGMAK 495 Query 764 -LGALSREERVERIP-WLAPECLPG-----GANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 L + ++ P W+APE + L+ A+D W G T++E+ F G+ P Sbjct 496 HLTGQRADLSLKGSPYWMAPELMQAVMQKDSNPDLAFAVDIWSLGCTIIEM-FTGKPPWS 554 Query 817 SRSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 + R +PE P+ C P +RP+ +L Sbjct 555 EFEGAAAMFKVMRDSPPIPESMSPEGKDFLRLCFQRNPAERPTASMLL 602 >sp|A7MBB4|M3K13_BOVIN Mitogen-activated protein kinase kinase kinase 13 OS=Bos taurus OX=9913 GN=MAP3K13 PE=2 SV=1 Length=966 Score = 101 bits (252), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 83/273 (30%), Positives = 120/273 (44%), Gaps = 39/273 (14%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI--LRTL 954 + +++ LG G G V L + E VA+K ++ + E DI LR L Sbjct 168 ISELQWLGSGAQGAVFLGKF------RAEEVAIKKVRE----------QNETDIKHLRKL 211 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAY 1013 H +II +KG C ++MEY G L + L +LL+ ++ I GM Y Sbjct 212 KHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNY 269 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 LH IHRDL + NVL+ + VKI DFG +K + + + V W APE + Sbjct 270 LHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDK----STKMSFAGTVAWMAPEVI 325 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + D+WSFGV L+ELLT P K ++ I G + Sbjct 326 RNEPVSEKVDIWSFGVVLWELLT-----GEIPYKDVDSSAIIWG---------VGSNSLH 371 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 LP P CP LMK W+++ RP+F + Sbjct 372 LPVPSTCPDGFKILMKQTWQSKTRNRPSFRQTL 404 Score = 62.0 bits (149), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 74/308 (24%), Positives = 119/308 (39%), Gaps = 54/308 (18%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 +A L Q V +EI++L LG G + V+ G+ R E Sbjct 146 GKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAEEVA------------ 193 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 + KV + + DI + ++ H ++ GVC + P ++ Sbjct 194 -------------IKKVREQNETDI--------KHLRKLKHPNIIAFKGVCTQAPCYCII 232 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLAR 744 EY HG L LR R P +++V + +AS ++YL ++H ++ N+L+ Sbjct 233 MEYCAHGQLYEVLRAGRKITP---RLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTH 289 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFG 801 + +K+SD G + ++ + W+APE + +S +D W FG Sbjct 290 -------TDAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFG 340 Query 802 ATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPS 858 L E+ GE P + S LP PS CP L Q + RPS Sbjct 341 VVLWEL-LTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKTRNRPS 399 Query 859 FRTILRDL 866 FR L L Sbjct 400 FRQTLMHL 407 >sp|Q54JG7|DST4_DICDI Serine/threonine-protein kinase dst4 OS=Dictyostelium discoideum OX=44689 GN=dst4 PE=3 SV=1 Length=485 Score = 99.8 bits (247), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 85/294 (29%), Positives = 136/294 (46%), Gaps = 33/294 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR-TLYHEHIIK 961 +G+G FG V C + N+ E+VA+K L+ + + S K+EI IL+ T+ +I+K Sbjct 27 IGQGSFG-VVCTCINTVNN---EVVAIKFLEME--GEENSSLKKEITILKNTVRCPYIVK 80 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHY 1019 Y GC E +L +VMEY GS+ D + SI L AQ+ QI EG+ YLH+ Sbjct 81 YHGCYIK--ENNLMIVMEYCDGGSILDIMQMCSITLTEAQIAAILYQIVEGLVYLHSNKI 138 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK-- 1077 +HRD+ A NVL++ K+ DFG++ + + ++ + SP +W +PE + K Sbjct 139 LHRDIKAGNVLVNKLGQAKLADFGVSAILV--NTGFKQKTVVGSP-YWMSPEVISPPKGS 195 Query 1078 --FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + +D+WS G+T E+ + PP L + + + L Sbjct 196 NGYDSKADIWSLGITAIEM-----AESKPPLFNLNPVKVI--------FVIPFRQAPTLE 242 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAPSVFSVC 1187 P E + C EA RP+ +L+ P +K E Q + C Sbjct 243 VPGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFIKKGKEHSQPTISEMVEQC 296 Score = 59.3 bits (142), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 55/236 (23%), Positives = 105/236 (44%), Gaps = 18/236 (8%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K L+ + + E L + V ++ HG ++ ++V EY + G + Sbjct 47 VAIKFLEMEGEENSSLKKEITILKNTVRCPYIVKYHGCYIKENNLMIVMEYCDGGSILDI 106 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 ++ + A + Q+ L YL + ++H ++ N+L+ +LG A KL+ Sbjct 107 MQMCSITLTEAQIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQA-------KLA 159 Query 759 DPGVGLGALS---REERVERIP-WLAPECL--PGGANSLSTAMDKWGFGATLLEICFDGE 812 D GV ++ +++ V P W++PE + P G+N + D W G T +E+ + + Sbjct 160 DFGVSAILVNTGFKQKTVVGSPYWMSPEVISPPKGSNGYDSKADIWSLGITAIEMA-ESK 218 Query 813 APLQSRSPSEKEHF--YQRQHRLPEPS--CPQLATLTSQCLTYEPTQRPSFRTILR 864 PL + +P + +++ L P P+ S CL E +RPS +L Sbjct 219 PPLFNLNPVKVIFVIPFRQAPTLEVPGNWSPEFNDFISVCLNKEADKRPSAVDLLN 274 >sp|Q9JLS3|TAOK2_RAT Serine/threonine-protein kinase TAO2 OS=Rattus norvegicus OX=10116 GN=Taok2 PE=1 SV=1 Length=1235 Score = 101 bits (252), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 72/209 (34%), Positives = 109/209 (52%), Gaps = 23/209 (11%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDI 950 ++ +R++G G FG V + D N E+VA+K + + G Q W+ +E+ Sbjct 25 EKLFSDLREIGHGSFGAV-YFARDVRNS---EVVAIKKM-SYSGKQSNEKWQDIIKEVRF 79 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQIC 1008 L+ L H + I+Y+GC E + LVMEY LGS D L H L ++ + A Sbjct 80 LQKLRHPNTIQYRGCYLR--EHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAVTHGAL 136 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +G+AYLH+ + IHRD+ A N+LL LVK+GDFG A + + + +P +W Sbjct 137 QGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSFV------GTP-YWM 189 Query 1069 APE---CLKEYKFYYASDVWSFGVTLYEL 1094 APE + E ++ DVWS G+T EL Sbjct 190 APEVILAMDEGQYDGKVDVWSLGITCIEL 218 Score = 38.1 bits (87), Expect = 0.60, Method: Compositional matrix adjust. Identities = 44/186 (24%), Positives = 67/186 (36%), Gaps = 14/186 (8%) Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780 L+YL + N++H +V NILL+ GL +KL D G V W+A Sbjct 138 GLAYLHSHNMIHRDVKAGNILLSEPGL-------VKLGDFGSASIMAPANSFVGTPYWMA 190 Query 781 PEC-LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-- 837 PE L +D W G T +E+ + S H Q + + Sbjct 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPALQSGHW 250 Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRD---LTRLQPHNLADVLTVNPDSPASDPTVFHK 894 CL P RP+ +L+ L P + D++ D+ + Sbjct 251 SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA-VRELDNLQY 309 Query 895 RYLKKI 900 R +KKI Sbjct 310 RKMKKI 315 >sp|P20792|DAF1_CAEEL Cell surface receptor daf-1 OS=Caenorhabditis elegans OX=6239 GN=daf-1 PE=1 SV=1 Length=669 Score = 100 bits (250), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 105/372 (28%), Positives = 157/372 (42%), Gaps = 73/372 (20%) Query 837 SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASD--PTVFHK 894 S P++A + Q T + SF + P+N+ D+L V ++ S PT HK Sbjct 233 SVPEVAPIEQQGSTMSTSAGNSFPP------GIMPNNMKDMLDVLEETSGSGMGPTTLHK 286 Query 895 RYLK-KIR---DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 + +IR +G G FG VS D GE VAVK A P + EI Sbjct 287 LTIGGQIRLTGRVGSGRFGNVS------RGDYRGEAVAVKVFNALDEPAFHK--ETEIFE 338 Query 951 LRTLYHEHIIKYKGCCE-DQG-EKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008 R L H ++++Y G D G L LV EY P GSL D+L +++ + + Sbjct 339 TRMLRHPNVLRYIGSDRVDTGFVTELWLVTEYHPSGSLHDFLLENTVNIETYYNLMRSTA 398 Query 1009 EGMAYLHAQ----------HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-------G 1051 G+A+LH Q HRD+ ++N+++ ND IGD GL+ + PE Sbjct 399 SGLAFLHNQIGGSKESNKPAMAHRDIKSKNIMVKNDLTCAIGDLGLSLSKPEDAASDIIA 458 Query 1052 HEYYRVREDGDSPVFWYAPECLKE------YKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 +E Y+ V + APE L ++ Y +DV+SF + ++E L C+ P Sbjct 459 NENYKC-----GTVRYLAPEILNSTMQFTVFESYQCADVYSFSLVMWETLCRCEDGDVLP 513 Query 1106 TKFLELIGIAQ--------GQMTVLRLTELLERGERLPRPDKCPC-----EVYHLM---K 1149 + +I + QM + T L RP + P E+ H+M K Sbjct 514 REAATVIPYIEWTDRDPQDAQMFDVVCTRRL-------RPTENPLWKDHPEMKHIMEIIK 566 Query 1150 NCWETEASFRPT 1161 CW S R T Sbjct 567 TCWNGNPSARFT 578 >sp|Q1HKZ5|M3K13_MOUSE Mitogen-activated protein kinase kinase kinase 13 OS=Mus musculus OX=10090 GN=Map3k13 PE=1 SV=1 Length=959 Score = 101 bits (251), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 83/273 (30%), Positives = 120/273 (44%), Gaps = 39/273 (14%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI--LRTL 954 + +++ LG G G V L + E VA+K ++ + E DI LR L Sbjct 167 ISELQWLGSGAQGAVFLGKF------RAEEVAIKKVRE----------QNETDIKHLRKL 210 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAY 1013 H +II +KG C ++MEY G L + L +LL+ ++ I GM Y Sbjct 211 KHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNY 268 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 LH IHRDL + NVL+ + VKI DFG +K + + + V W APE + Sbjct 269 LHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSD----KSTKMSFAGTVAWMAPEVI 324 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + D+WSFGV L+ELLT P K ++ I G + Sbjct 325 RNEPVSEKVDIWSFGVVLWELLT-----GEIPYKDVDSSAIIWG---------VGSNSLH 370 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 LP P CP LMK W+++ RP+F + Sbjct 371 LPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTL 403 Score = 64.3 bits (155), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 74/299 (25%), Positives = 118/299 (39%), Gaps = 54/299 (18%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L Q V +EI++L LG G + V+ G+ R E Sbjct 154 LQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAEEV---------------------- 191 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 + KV + + DI + ++ H ++ GVC + P ++ EY HG L Sbjct 192 ---AIKKVREQNETDI--------KHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQL 240 Query 696 DVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 LR R P +++V + +AS ++YL ++H ++ N+L+ + Sbjct 241 YEVLRAGRKITP---RLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTH-------TD 290 Query 754 FIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +K+SD G + ++ + W+APE + +S +D W FG L E+ Sbjct 291 AVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVVLWEL-LT 347 Query 811 GEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866 GE P + S LP PS CP L Q +P RPSFR L L Sbjct 348 GEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHL 406 >sp|Q54XQ2|RCKA_DICDI RGS domain-containing serine/threonine-protein kinase A OS=Dictyostelium discoideum OX=44689 GN=rckA PE=1 SV=1 Length=1125 Score = 101 bits (252), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 69/252 (27%), Positives = 118/252 (47%), Gaps = 25/252 (10%) Query 924 GEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982 G+ VA+K L + C + +K+E+ ++ H+++ + G + +K L EY Sbjct 863 GKDVAIKVLGPEVCVHFDLNEFKREVALMSIFKHDNLARCLGAGQ-YDDKYFHLT-EYCH 920 Query 983 LGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040 GSL YL R++I Q L FA I GM YLH+ IHRDL + N+LL +KI Sbjct 921 NGSLFSYLRDQRNNISFGQRLHFALGIARGMRYLHSMSIIHRDLKSMNILLTKRLKIKIV 980 Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100 DFG ++ ++Y G W APE + DV+S+ + L+E+ T Sbjct 981 DFGTSRV---ANKYNMTTHVGTQA--WMAPEIFTSRTYTNKVDVYSYAIILFEIFTRKS- 1034 Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 A + + + ++ +GER P + +++K CW+ + S RP Sbjct 1035 --------------AYDENANINIPNMVMKGERPELPKDMQTSISNIIKKCWQQKPSNRP 1080 Query 1161 TFENLIPILKTV 1172 +F ++ L+++ Sbjct 1081 SFIKIVAYLESI 1092 Score = 67.0 bits (162), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 61/242 (25%), Positives = 108/242 (45%), Gaps = 22/242 (9%) Query 630 GRDRGQELRVVLKVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 G+ +G++ V +KVL P H D+ F +LMS H +LA G + + Sbjct 859 GQYKGKD--VAIKVLGPEVCVHFDLN-EFKREVALMSIFKHDNLARCLGAGQYDDKYFHL 915 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA-RL 745 TEY +G L +LR +R ++ ++ A +A + YL + +++H ++ NILL RL Sbjct 916 TEYCHNGSLFSYLRDQRNNISFGQRLHFALGIARGMRYLHSMSIIHRDLKSMNILLTKRL 975 Query 746 GLAEGTSPFIKLSDPGVGLGA--LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 IK+ D G A + V W+APE + + + +D + + Sbjct 976 K--------IKIVDFGTSRVANKYNMTTHVGTQAWMAPEIF--TSRTYTNKVDVYSYAII 1025 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRT 861 L EI F ++ + + + R LP+ ++ + +C +P+ RPSF Sbjct 1026 LFEI-FTRKSAYDENANINIPNMVMKGERPELPKDMQTSISNIIKKCWQQKPSNRPSFIK 1084 Query 862 IL 863 I+ Sbjct 1085 IV 1086 >sp|O14305|SID1_SCHPO Serine/threonine-protein kinase sid1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=sid1 PE=1 SV=1 Length=471 Score = 99.4 bits (246), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 57/196 (29%), Positives = 102/196 (52%), Gaps = 10/196 (5%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +R LG G FG V + + +G+++A+K + + G + +QE+ +L ++ Sbjct 12 LRKLGSGSFGVV----WKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLSNCNSSNV 67 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I+Y GC D +L ++ME++ GS+ L + + + +++ G+ YLH Q+ Sbjct 68 IQYYGCFVDG--YTLWILMEHMDGGSVSGLLKMGRLNEQVISIILREVLYGLNYLHGQNK 125 Query 1020 IHRDLAARNVLLDNDR-LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ A N+LL + VK+ DFG+A + R FW APE +++ + Sbjct 126 IHRDIKAANILLSSSTGNVKLADFGVAAQLSNAASR---RHTFVGTPFWMAPEVIQQTSY 182 Query 1079 YYASDVWSFGVTLYEL 1094 A+D+WS G+T E+ Sbjct 183 GLAADIWSLGITAIEM 198 Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 52/221 (24%), Positives = 93/221 (42%), Gaps = 39/221 (18%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 ++S + +++ +G V G ++ E+++ G + L+ R + + ++ +++ Sbjct 58 MLSNCNSSNVIQYYGCFVDGYTLWILMEHMDGGSVSGLLKMGRLNEQVI--SIILREVLY 115 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---GALSREERVERIP 777 L+YL +N +H ++ NILL+ ++ +KL+D GV A SR P Sbjct 116 GLNYLHGQNKIHRDIKAANILLS------SSTGNVKLADFGVAAQLSNAASRRHTFVGTP 169 Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL-------------QSRSPSEK 823 W+APE + + L A D W G T +E+ +G P QS P Sbjct 170 FWMAPEVIQQTSYGL--AADIWSLGITAIEMA-NGIPPRATMHPMRVIFEIPQSEPPKLD 226 Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 +HF P S CL P R S + +L+ Sbjct 227 DHF-----------SPTFRDFVSCCLDLNPNMRWSAKELLQ 256 >sp|P43293|PBL11_ARATH Probable serine/threonine-protein kinase PBL11 OS=Arabidopsis thaliana OX=3702 GN=PBL11 PE=1 SV=2 Length=389 Score = 98.2 bits (243), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 95/292 (33%), Positives = 140/292 (48%), Gaps = 32/292 (11%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +GEG FG V D P+ GTG ++AVK L + HR W EI+ L L H Sbjct 74 VGEGGFGCVFKGWIDESSLAPSKPGTGIVIAVKRLNQEGFQGHRE-WLAEINYLGQLDHP 132 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMA 1012 +++K G C + E+ LV E++ GSL ++L R L + A G+A Sbjct 133 NLVKLIGYCLE--EEHRLLVYEFMTRGSLENHLFRRGTFYQPLSWNTRVRMALGAARGLA 190 Query 1013 YLH-AQ-HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG-HEYYRVREDGDSPVFWYA 1069 +LH AQ I+RD A N+LLD++ K+ DFGLA+ P G + + R G + A Sbjct 191 FLHNAQPQVIYRDFKASNILLDSNYNAKLSDFGLARDGPMGDNSHVSTRVMGTQG--YAA 248 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT---HCDSSQSPPTKFLELIGIAQGQMT----VL 1122 PE L SDV+SFGV L ELL+ D +Q P L+ A+ +T +L Sbjct 249 PEYLATGHLSVKSDVYSFGVVLLELLSGRRAIDKNQ--PVGEHNLVDWARPYLTNKRRLL 306 Query 1123 RLTELLERGE-RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 R+ + +G+ L R K L +C +A RPT ++ ++ +H Sbjct 307 RVMDPRLQGQYSLTRALKIAV----LALDCISIDAKSRPTMNEIVKTMEELH 354 Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 68/290 (23%), Positives = 116/290 (40%), Gaps = 41/290 (14%) Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 DE L P + G + + +K L+ + + + Q+ H +L + G C+ Sbjct 88 DESSLAPSKP-GTGIVIAVKRLNQEGFQGHREWLAEINYLGQLDHPNLVKLIGYCLEEEH 146 Query 683 NIMVTEYVEHGPLDVWL-RRERGHVPMAWKMVVAQQLASA--LSYLENKN--LVHGNVCG 737 ++V E++ G L+ L RR + P++W V L +A L++L N +++ + Sbjct 147 RLLVYEFMTRGSLENHLFRRGTFYQPLSWNTRVRMALGAARGLAFLHNAQPQVIYRDFKA 206 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVE-RI----PWLAPECLPGGANSL 791 NILL ++ KLSD G+ G + V R+ + APE L G L Sbjct 207 SNILL-------DSNYNAKLSDFGLARDGPMGDNSHVSTRVMGTQGYAAPEYLATG--HL 257 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH-------FYQRQHRLPEPSCPQL--- 841 S D + FG LLE+ G + P + + + + RL P+L Sbjct 258 SVKSDVYSFGVVLLEL-LSGRRAIDKNQPVGEHNLVDWARPYLTNKRRLLRVMDPRLQGQ 316 Query 842 ---------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 A L C++ + RP+ I++ + L A NP Sbjct 317 YSLTRALKIAVLALDCISIDAKSRPTMNEIVKTMEELHIQKEASKEQQNP 366 >sp|A7E3S4|RAF1_BOVIN RAF proto-oncogene serine/threonine-protein kinase OS=Bos taurus OX=9913 GN=RAF1 PE=2 SV=1 Length=648 Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 68/200 (34%), Positives = 102/200 (51%), Gaps = 17/200 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+ Sbjct 355 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILL 407 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ Sbjct 408 FMGY---MTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 464 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076 IHRD+ + N+ L VKIGDFGLA +V + S + W APE ++ Sbjct 465 IHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-ILWMAPEVIRMQDNN 523 Query 1077 KFYYASDVWSFGVTLYELLT 1096 F + SDV+S+G+ LYEL+T Sbjct 524 PFSFQSDVYSYGIVLYELMT 543 Score = 64.3 bits (155), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 71/286 (25%), Positives = 127/286 (44%), Gaps = 32/286 (11%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688 G+ G +LKV+DP+ AF +++ + H ++ G + +N+ +VT+ Sbjct 366 GKWHGDVAVKILKVVDPTPEQFQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 422 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + E L L + M + +A+Q A + YL KN++H ++ NI L Sbjct 423 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF-----LH 477 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANS-LSTAMDKWGFG 801 EG + +K+ D G+ G+ E+ I W+APE + N+ S D + +G Sbjct 478 EGLT--VKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDNNPFSFQSDVYSYG 535 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854 L E+ GE P + ++ F R + P+ S CP+ + L + C+ Sbjct 536 IVLYEL-MTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKE 594 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 +RP F IL + LQ H+L + + AS+P++ + + I Sbjct 595 ERPLFPQILSSIELLQ-HSLPKI-----NRSASEPSLHRAAHTEDI 634 >sp|Q54TA1|DRKC_DICDI Probable serine/threonine-protein kinase drkC OS=Dictyostelium discoideum OX=44689 GN=drkC PE=3 SV=1 Length=749 Score = 100 bits (250), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 76/249 (31%), Positives = 118/249 (47%), Gaps = 23/249 (9%) Query 924 GEMVAVKALK--ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 G +VA+K K + + QE I+ L H +I ++ G C + E + +VMEY+ Sbjct 512 GIIVAIKKAKLLNEDDEDFLNELAQEATIMSQLRHPNICQFLGTCNNPPE--ILIVMEYM 569 Query 982 PLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDNDRLV 1037 PLGSL L P S+ ++ A I +GM YLH IHRDL + N+L+D V Sbjct 570 PLGSLYRILHDPSISLDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDEHYRV 629 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 KI DFGL+ + + +P W APE L+ + +DV+SF + L+E++T Sbjct 630 KISDFGLSTRFKKHLDKKTAMTPVGTPC-WTAPEVLRNDPYTEKADVFSFAIVLWEIVTR 688 Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157 D Q PT F +I + Q ++ R P + L+ CW + Sbjct 689 EDPYQGMPT-FQIVISVGQHKL-------------RPIVPPQVSAPFTRLITECWSEDPQ 734 Query 1158 FRPTFENLI 1166 RP+F+ ++ Sbjct 735 QRPSFQEIV 743 Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 61/238 (26%), Positives = 102/238 (43%), Gaps = 25/238 (11%) Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 K+L+ D + A++MSQ+ H ++ G C PE ++V EY+ G L L Sbjct 521 KLLNEDDEDFLNELAQEATIMSQLRHPNICQFLGTCNNPPEILIVMEYMPLGSLYRILHD 580 Query 702 ERGHVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + +A +A ++YL + ++H ++ N+L+ +K+SD Sbjct 581 PSISLDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDE-------HYRVKISD 633 Query 760 PGVG------LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ L + V W APE L + + D + F L EI E Sbjct 634 FGLSTRFKKHLDKKTAMTPVGTPCWTAPEVLRN--DPYTEKADVFSFAIVLWEIV-TRED 690 Query 814 PLQSRSPSEKEHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 P Q P+ + QH+L P+ S P L ++C + +P QRPSF+ I++ L Sbjct 691 PYQGM-PTFQIVISVGQHKLRPIVPPQVSAP-FTRLITECWSEDPQQRPSFQEIVKRL 746 >sp|P23437|CDK2_XENLA Cyclin-dependent kinase 2 OS=Xenopus laevis OX=8355 GN=cdk2 PE=1 SV=3 Length=297 Score = 96.3 bits (238), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 70/207 (34%), Positives = 106/207 (51%), Gaps = 19/207 (9%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955 +K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ L Sbjct 4 FQKVEKIGEGTYGVV----YKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELN 59 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYV--PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013 H +I+K E L LV E++ L D I LA + + Q+ +G+A+ Sbjct 60 HPNIVKLLDVI--HTENKLYLVFEFLNQDLKKFMDGSNISGISLALVKSYLFQLLQGLAF 117 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070 H+ +HRDL +N+L+++D +K+ DFGLA+A VP + V WY AP Sbjct 118 CHSHRVLHRDLKPQNLLINSDGAIKLADFGLARAFGVPVRTFTHEV------VTLWYRAP 171 Query 1071 ECLKEYKFY-YASDVWSFGVTLYELLT 1096 E L KFY A D+WS G E++T Sbjct 172 EILLGCKFYSTAVDIWSLGCIFAEMIT 198 >sp|Q9SZ67|WRK19_ARATH Probable WRKY transcription factor 19 OS=Arabidopsis thaliana OX=3702 GN=WRKY19 PE=1 SV=1 Length=1895 Score = 101 bits (252), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 84/274 (31%), Positives = 134/274 (49%), Gaps = 43/274 (16%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEID----ILRTLYHE 957 LG G G V Y+ + G+ A K + D G Q W Q+++ +L L H+ Sbjct 1632 LGRGSLGSV----YEGIS-ADGDFFAFKEVSLLDQGSQAHE-WIQQVEGGIALLSQLQHQ 1685 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +I++Y+G +D E +L + +E V GSLR R+ +G + + L+ +QI +G+ YLH + Sbjct 1686 NIVRYRGTTKD--ESNLYIFLELVTQGSLRKLYQRNQLGDSVVSLYTRQILDGLKYLHDK 1743 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-WYAPECL--- 1073 +IHR++ NVL+D + VK+ DFGLAK + +R +P + W APE + Sbjct 1744 GFIHRNIKCANVLVDANGTVKLADFGLAKVM----SLWR------TPYWNWMAPEVILNP 1793 Query 1074 KEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 K+Y Y +D+WS G T+ E+LT P LE IG A + +L ++ Sbjct 1794 KDYDGYGTPADIWSLGCTVLEMLTG-----QIPYSDLE-IGTALYNIGTGKLPKI----- 1842 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 PD + + C + RPT L+ Sbjct 1843 ----PDILSLDARDFILTCLKVNPEERPTAAELL 1872 Score = 52.4 bits (124), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 54/213 (25%), Positives = 89/213 (42%), Gaps = 24/213 (11%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQL 718 +L+SQ+ H ++ G + E V G L ++ R + G ++ + +Q+ Sbjct 1677 ALLSQLQHQNIVRYRGTTKDESNLYIFLELVTQGSLRKLYQRNQLGDSVVS---LYTRQI 1733 Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPW 778 L YL +K +H N+ N+L+ A GT +KL+D GL + R W Sbjct 1734 LDGLKYLHDKGFIHRNIKCANVLVD----ANGT---VKLAD--FGLAKVMSLWRTPYWNW 1784 Query 779 LAPECL--PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836 +APE + P + T D W G T+LE+ G+ P S E P Sbjct 1785 MAPEVILNPKDYDGYGTPADIWSLGCTVLEM-LTGQIPY---SDLEIGTALYNIGTGKLP 1840 Query 837 SCPQLATLTSQ-----CLTYEPTQRPSFRTILR 864 P + +L ++ CL P +RP+ +L Sbjct 1841 KIPDILSLDARDFILTCLKVNPEERPTAAELLN 1873 >sp|Q6GPK9|TAOK2_XENLA Serine/threonine-protein kinase TAO2 OS=Xenopus laevis OX=8355 GN=taok2 PE=2 SV=1 Length=1025 Score = 100 bits (250), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 81/236 (34%), Positives = 119/236 (50%), Gaps = 32/236 (14%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956 +R++G G FG V + D N+ E+VA+K + + G Q W+ +E+ L+ L H Sbjct 31 LREIGHGSFGAV-YFARDIRNN---EVVAIKKM-SYSGKQSNEKWQDIIKEVKFLQKLRH 85 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014 + I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL Sbjct 86 PNTIEYKGCY--LREHTAWLVMEYC-LGSASDLLEVHKKPLQEMEIAAITHGALQGLAYL 142 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071 H + IHRD+ A N+LL LVK+GDFG A + + + +P +W APE Sbjct 143 HNHNMIHRDVKAGNILLTEPGLVKLGDFGSASIMAPANSFV------GTP-YWMAPEVIL 195 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP----TKFLELIGIAQGQMTVLR 1123 + E ++ DVWS G+T EL + + PP L IAQ + VL+ Sbjct 196 AMDEGQYDGKVDVWSLGITSIEL-----AERKPPLFNMNAMSALYHIAQNESPVLQ 246 Score = 41.2 bits (95), Expect = 0.066, Method: Compositional matrix adjust. Identities = 46/184 (25%), Positives = 66/184 (36%), Gaps = 12/184 (7%) Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781 L+YL N N++H +V NILL GL +KL D G V W+AP Sbjct 139 LAYLHNHNMIHRDVKAGNILLTEPGL-------VKLGDFGSASIMAPANSFVGTPYWMAP 191 Query 782 EC-LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--C 838 E L +D W G T +E+ + S H Q + + + + Sbjct 192 EVILAMDEGQYDGKVDVWSLGITSIELAERKPPLFNMNAMSALYHIAQNESPVLQSNHWS 251 Query 839 PQLATLTSQCLTYEPTQRPSFRTIL--RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896 CL P RP+ +L R L R +P + L + R Sbjct 252 EYFRNFVDSCLQKIPQDRPTSDMLLKHRFLQRERPQTVIMELIQRTKDAVRELDNLQYRK 311 Query 897 LKKI 900 +KKI Sbjct 312 MKKI 315 >sp|O61125|STK4_DICDI Serine/threonine-protein kinase 4 homolog A OS=Dictyostelium discoideum OX=44689 GN=krsA PE=1 SV=1 Length=461 Score = 99.0 bits (245), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 71/279 (25%), Positives = 131/279 (47%), Gaps = 33/279 (12%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 +++ + LGEG +G V Y N TG +VA+K + D ++EI ++ Sbjct 17 EKFFTIVEKLGEGSYGSV----YKAINISTGIVVAIKKVSVD---NDLEDMEKEISFMKQ 69 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGM 1011 +I+ Y + E + +VME+ GS+ D + L+ Q+ + ++ + +G+ Sbjct 70 CKSPYIVTYYASFRKENE--VWIVMEHCGAGSVCDAMKITDKTLSEDQIAVVSRDVLQGL 127 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 AYLH+ IHRD+ A N+L+++ K+ DFG++ + + R+ FW APE Sbjct 128 AYLHSVRKIHRDIKAGNILMNHKGESKLADFGVSGQLSDTMAK---RQTVIGTPFWMAPE 184 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 ++E + Y +D+WS+G+T E+ ++S P F + +R+ ++ Sbjct 185 VIQEIGYDYKADIWSYGITCIEM------AESKPPLF---------NVHPMRVIFMIPNP 229 Query 1132 ER----LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 R L P+K E + C + RP+ E L+ Sbjct 230 SRPPPKLTEPEKWSPEFNDFLAKCLTRKPELRPSAEELL 268 Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 34/180 (19%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSR 769 VV++ + L+YL + +H ++ NIL+ G + KL+D GV +++ Sbjct 118 VVSRDVLQGLAYLHSVRKIHRDIKAGNILMNHKGES-------KLADFGVSGQLSDTMAK 170 Query 770 EERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 + V P W+APE + D W +G T +E+ +S+ P H + Sbjct 171 RQTVIGTPFWMAPEVIQEIGYDYKA--DIWSYGITCIEMA-------ESKPPLFNVHPMR 221 Query 829 RQHRLPEPS------------CPQLATLTSQCLTYEPTQRPSFRTILRD--LTRLQPHNL 874 +P PS P+ ++CLT +P RPS +L+ +T+ + H+L Sbjct 222 VIFMIPNPSRPPPKLTEPEKWSPEFNDFLAKCLTRKPELRPSAEELLKHPFITKAKSHSL 281 >sp|P79749|PGFRB_TAKRU Platelet-derived growth factor receptor beta OS=Takifugu rubripes OX=31033 GN=pdgfrb PE=3 SV=1 Length=1048 Score = 100 bits (250), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 70/222 (32%), Positives = 105/222 (47%), Gaps = 29/222 (13%) Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 ++QG + LV+ P + D LL F+ Q+ +GM +L +++ +HRDLAA Sbjct 776 QEQGGGRVDLVISDSPALTYDD-----------LLGFSYQVAKGMEFLASKNCVHRDLAA 824 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RNVL+ +LVKI DFGLA+ + Y + P+ W APE + + SDVWS Sbjct 825 RNVLICEGKLVKICDFGLARDIMHDSNYIS-KGSTFLPLKWMAPESIFHNLYTTLSDVWS 883 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 +G+ L+E+ T + P EL L+RG R+ +P EVY Sbjct 884 YGILLWEIFT-LGGTPYPDLPMNEL------------FYSPLKRGYRMAKPAHASDEVYE 930 Query 1147 LMKNCWETEASFRPTFENLI----PILKTVHEKYQGQAPSVF 1184 +MK CW+ RP F L+ +L ++K Q F Sbjct 931 IMKRCWDETFEKRPDFSFLVHCVGDMLTDSYKKKYSQVNETF 972 Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 43/174 (25%), Positives = 77/174 (44%), Gaps = 30/174 (17%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L +KN VH ++ RN+L + EG +K+ D G+ + + + Sbjct 804 QVAKGMEFLASKNCVHRDLAARNVL-----ICEGK--LVKICDFGLARDIMHDSNYISKG 856 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--- 827 + W+APE + N +T D W +G L EI G P +E FY Sbjct 857 STFLPLKWMAPESI--FHNLYTTLSDVWSYGILLWEIFTLGGTPYPDLPMNEL--FYSPL 912 Query 828 QRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 +R +R+ +P + ++ + +C +RP F ++ H + D+LT Sbjct 913 KRGYRMAKPAHASDEVYEIMKRCWDETFEKRPDFSFLV--------HCVGDMLT 958 Score = 40.4 bits (93), Expect = 0.11, Method: Compositional matrix adjust. Identities = 35/108 (32%), Positives = 45/108 (42%), Gaps = 4/108 (4%) Query 901 RDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY-HEH 958 R LG G FG+V + ++ + VAVK LKA E+ I+ L H + Sbjct 600 RTLGSGAFGRVVEATAHGLSHSQSSIKVAVKMLKATARRSETQALMSELKIMSHLGPHLN 659 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006 I+ C G L LV EY G L DYL R+ Q L Q Sbjct 660 IVNLLAACTKHG--PLYLVTEYCRYGDLVDYLHRNKHTFLQYYLDKNQ 705 >sp|Q9Z2W1|STK25_MOUSE Serine/threonine-protein kinase 25 OS=Mus musculus OX=10090 GN=Stk25 PE=1 SV=2 Length=426 Score = 98.2 bits (243), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 77/274 (28%), Positives = 125/274 (46%), Gaps = 36/274 (13%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 K+ +G+G FG+V Y ++ T E+VA+K + + +QEI +L + Sbjct 22 KLDRIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPY 77 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I +Y G + L ++MEY+ GS D L + + ++I +G+ YLH++ Sbjct 78 ITRYFGSYLKSTK--LWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSER 135 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ A NVLL VK+ DFG+A + + R FW APE +K+ + Sbjct 136 KIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQ---IKRNTFVGTPFWMAPEVIKQSAY 192 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 + +D+WS G+T EL + PP L M VL L +P+ + Sbjct 193 DFKADIWSLGITAIEL-----AKGEPPNSDLH-------PMRVLFL---------IPKNN 231 Query 1139 KCPCEVYH------LMKNCWETEASFRPTFENLI 1166 E +H ++ C + FRPT + L+ Sbjct 232 PPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELL 265 Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 64/298 (21%), Positives = 121/298 (41%), Gaps = 60/298 (20%) Query 583 RVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 RVD +E+ T+L +G+G+ VY+G +D+ V V + Sbjct 13 RVDPEELFTKLDRIGKGSFGEVYKG--------------IDNHTKEV----------VAI 48 Query 642 KVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWL 699 K++D D + +++SQ ++ G ++ + ++ EY+ G LD+ Sbjct 49 KIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLL- 107 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + G + + + +++ L YL ++ +H ++ N+LL+ G +KL+D Sbjct 108 --KPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQG-------DVKLAD 158 Query 760 PGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 GV G L+ R V W+APE + A D W G T +E+ Sbjct 159 FGVA-GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKA--DIWSLGITAIELA------ 209 Query 815 LQSRSPSEKEHFYQRQHRLPEPSCPQL--------ATLTSQCLTYEPTQRPSFRTILR 864 + P+ H + +P+ + P L CL +P RP+ + +L+ Sbjct 210 -KGEPPNSDLHPMRVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLK 266 >sp|Q5UQG7|YR818_MIMIV Putative serine/threonine-protein kinase/receptor R818 OS=Acanthamoeba polyphaga mimivirus OX=212035 GN=MIMI_R818 PE=3 SV=1 Length=1651 Score = 101 bits (251), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 80/287 (28%), Positives = 132/287 (46%), Gaps = 26/287 (9%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDI 950 FH+ L + LG G G+V + G VAVK L ++ +KQEI Sbjct 790 FHE--LDFMESLGSGGSGEVFKAMWK------GTEVAVKKLVNSNITKDAERNFKQEIHR 841 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL---FAQQI 1007 + +L H +++ + ++ +VME++ LGSL D L + +L A Q Sbjct 842 MTSLRHPNVVLFMAASTR--PPNMCIVMEFMSLGSLYDLLGNELVTEIPPVLRIRIAYQA 899 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 +GM +LH+ +HRDL + N+LLD+ VK+ DFGL K +ED + W Sbjct 900 AKGMHFLHSSDIVHRDLKSLNLLLDSKWNVKVSDFGLTKIKDNNKGKSSTKEDSVCSIQW 959 Query 1068 YAPECLKEYK--FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 APE L E + Y +DV+SFG+ ++EL+ T+ IG++ + V + Sbjct 960 TAPEVLSEKQDIDYILADVYSFGIIMWELM----------TRLRPYIGLSPAAIAVAVIR 1009 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + L + + + L+ CW + RP+F ++ L T+ Sbjct 1010 DNLRPEIQEEDINLMSSDYVELVNICWHKDTMIRPSFLEIMTKLSTL 1056 Score = 99.0 bits (245), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 80/269 (30%), Positives = 123/269 (46%), Gaps = 31/269 (12%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G +G V++ + N VAVK +K + ++ EI L L H HI Sbjct 1398 KQIGVGSYGIVNMGKWKNIN------VAVKKFVKQKIDEKQMLEFRAEIAFLSQLRHPHI 1451 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018 I G C + ++ +V E++ GSLR+ + + Q G+ YLH Sbjct 1452 ILMIGACLKR--PNICIVTEFMGNGSLRNVIKTTKPEWKLKIKMLYQTALGIGYLHNSDP 1509 Query 1019 -YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ N+L+D+ VKI DFG A+ E R +P W APE ++ K Sbjct 1510 IIIHRDIKPSNILVDDSMNVKIADFGFARIKEENSVMTRC----GTPC-WTAPEIIRGEK 1564 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + DV+SFG+ ++E+LT C S F+++ M +L G R P Sbjct 1565 YTEKVDVFSFGIVMWEVLT-CKEPFS-GCNFMKV------SMDIL-------EGARPQIP 1609 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 CP + LMK CW + RP+ E++I Sbjct 1610 SDCPIDFTKLMKQCWHAKPDKRPSMEDVI 1638 Score = 59.7 bits (143), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 55/231 (24%), Positives = 99/231 (43%), Gaps = 34/231 (15%) Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 L F + +SQ+ H H+ + G C++ P +VTE++ +G L ++ + + KM Sbjct 1434 LEFRAEIAFLSQLRHPHIILMIGACLKRPNICIVTEFMGNGSLRNVIKTTKPEWKLKIKM 1493 Query 713 VVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + Q A + YL N + ++H ++ NIL+ S +K++D G + E Sbjct 1494 L--YQTALGIGYLHNSDPIIIHRDIKPSNILV-------DDSMNVKIAD--FGFARIKEE 1542 Query 771 ERVER---IP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 V P W APE + G + +D + FG + E+ L + P +F Sbjct 1543 NSVMTRCGTPCWTAPEIIRG--EKYTEKVDVFSFGIVMWEV-------LTCKEPFSGCNF 1593 Query 827 YQRQHRLPEPSCPQL--------ATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + E + PQ+ L QC +P +RPS ++ L + Sbjct 1594 MKVSMDILEGARPQIPSDCPIDFTKLMKQCWHAKPDKRPSMEDVIMGLNDM 1644 Score = 53.9 bits (128), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 56/246 (23%), Positives = 98/246 (40%), Gaps = 11/246 (4%) Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 +G E+ V V D F + M+ + H ++ R P +V E++ Sbjct 813 KGTEVAVKKLVNSNITKDAERNFKQEIHRMTSLRHPNVVLFMAASTRPPNMCIVMEFMSL 872 Query 693 GPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEG 750 G L L E +P ++ +A Q A + +L + ++VH ++ N+LL ++ + Sbjct 873 GSLYDLLGNELVTEIPPVLRIRIAYQAAKGMHFLHSSDIVHRDLKSLNLLLDSKWNVKVS 932 Query 751 TSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K+ D G + ++E+ V I W APE L + D + FG + E+ Sbjct 933 DFGLTKIKDNNKGKSS-TKEDSVCSIQWTAPEVLSEKQDIDYILADVYSFGIIMWEL-MT 990 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ-------CLTYEPTQRPSFRTIL 863 P SP+ R + PE + ++S C + RPSF I+ Sbjct 991 RLRPYIGLSPAAIAVAVIRDNLRPEIQEEDINLMSSDYVELVNICWHKDTMIRPSFLEIM 1050 Query 864 RDLTRL 869 L+ L Sbjct 1051 TKLSTL 1056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens OX=9606 GN=BRAF PE=1 SV=4 Length=766 Score = 100 bits (249), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 78/274 (28%), Positives = 123/274 (45%), Gaps = 35/274 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK L PQ +K E+ +LR H +I+ Sbjct 463 IGSGSFGTV----YKGKWHGD---VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 515 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + L +V ++ SL +L + +L+ A+Q +GM YLHA+ Sbjct 516 FMGYST---KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSI 572 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076 IHRDL + N+ L D VKIGDFGLA ++ + S + W APE ++ + Sbjct 573 IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGS-ILWMAPEVIRMQDKN 631 Query 1077 KFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + SDV++FG+ LYEL+T + + + F+ G ++ +R Sbjct 632 PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVR--------- 682 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 CP + LM C + + RP F ++ Sbjct 683 -----SNCPKAMKRLMAECLKKKRDERPLFPQIL 711 Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 60/254 (24%), Positives = 106/254 (42%), Gaps = 24/254 (9%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G+ G +L V P+ + AF ++ + H ++ G + P+ +VT++ Sbjct 474 GKWHGDVAVKMLNVTAPTPQQLQ-AFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQW 531 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 E L L M + +A+Q A + YL K+++H ++ NI L Sbjct 532 CEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE----- 586 Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802 +K+ D G+ G+ E+ I W+APE + N S D + FG Sbjct 587 --DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGI 644 Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855 L E+ G+ P + + ++ F R + P+ S CP+ + L ++CL + + Sbjct 645 VLYEL-MTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDE 703 Query 856 RPSFRTILRDLTRL 869 RP F IL + L Sbjct 704 RPLFPQILASIELL 717 >sp|O49839|PBL2_ARATH Probable serine/threonine-protein kinase PBL2 OS=Arabidopsis thaliana OX=3702 GN=PBL2 PE=1 SV=1 Length=426 Score = 98.2 bits (243), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 78/207 (38%), Positives = 108/207 (52%), Gaps = 20/207 (10%) Query 903 LGEGHFGKVSLYCYDPTN-----DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LGEG FG V D T+ G+G +VAVK LK + G Q W E++ L L H Sbjct 92 LGEGGFGCVFKGWIDQTSLTASRPGSGIVVAVKQLKPE-GFQGHKEWLTEVNYLGQLSHP 150 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI------CEGM 1011 +++ G C +GE L LV E++P GSL ++L R AQ L +A ++ +G+ Sbjct 151 NLVLLVGYCA-EGENRL-LVYEFMPKGSLENHLFRRG---AQPLTWAIRMKVAVGAAKGL 205 Query 1012 AYLH--AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 +LH I+RD A N+LLD D K+ DFGLAKA P G + V + A Sbjct 206 TFLHEAKSQVIYRDFKAANILLDADFNAKLSDFGLAKAGPTGDNTH-VSTKVIGTHGYAA 264 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096 PE + + SDV+SFGV L EL++ Sbjct 265 PEYVATGRLTAKSDVYSFGVVLLELIS 291 Score = 56.2 bits (134), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 78/327 (24%), Positives = 127/327 (39%), Gaps = 57/327 (17%) Query 575 NLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 NL +F+ + K Q + LG+G V++G + D+ L R Sbjct 70 NLKAFTFNELKNATKNFRQDNLLGEGGFGCVFKGWI--------------DQTSLTASRP 115 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 G + V +K L P + + + Q+SH +L + G C G ++V E++ Sbjct 116 -GSGIVVAVKQLKPEGFQGHKEWLTEVNYLGQLSHPNLVLLVGYCAEGENRLLVYEFMPK 174 Query 693 GPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLA 748 G L+ L R RG P+ W +M VA A L++L +++ + NILL Sbjct 175 GSLENHLFR-RGAQPLTWAIRMKVAVGAAKGLTFLHEAKSQVIYRDFKAANILL------ 227 Query 749 EGTSPF-IKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFG 801 + F KLSD G+ + + + + APE + G L+ D + FG Sbjct 228 --DADFNAKLSDFGLAKAGPTGDNTHVSTKVIGTHGYAAPEYVATG--RLTAKSDVYSFG 283 Query 802 ATLLEICFDGEAPLQSRSPSE--------------KEHFYQRQHRL----PEPSCPQLAT 843 LLE+ A S +E ++ F +L P+ A Sbjct 284 VVLLELISGRRAMDNSNGGNEYSLVDWATPYLGDKRKLFRIMDTKLGGQYPQKGAFTAAN 343 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQ 870 L QCL + RP +L L +L+ Sbjct 344 LALQCLNPDAKLRPKMSEVLVTLEQLE 370 >sp|Q6QNF3|PGFRB_CANLF Platelet-derived growth factor receptor beta OS=Canis lupus familiaris OX=9615 GN=PDGFRB PE=2 SV=1 Length=1103 Score = 100 bits (250), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 58/168 (35%), Positives = 87/168 (52%), Gaps = 14/168 (8%) Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + L+ F+ Q+ GM +L +++ +HRDLAARNVL+ +LVKI DFGLA+ + Y Sbjct 798 LSYTDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNY 857 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + P+ W APE + + SDVWSFG+ L+E+ T T + EL Sbjct 858 IS-KGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGG------TPYPELPMN 910 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 Q ++RG R+ +P E+Y +M+ CWE + RP F Sbjct 911 EQ-------FYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPF 951 Score = 49.3 bits (116), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 42/155 (27%), Positives = 71/155 (46%), Gaps = 24/155 (15%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A+ + +L +KN VH ++ RN+L + EG +K+ D G+ + + + Sbjct 809 QVANGMEFLASKNCVHRDLAARNVL-----ICEGK--LVKICDFGLARDIMRDSNYISKG 861 Query 776 -----IPWLAPECLPGGANSLSTAM-DKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-- 827 + W+APE + NSL T + D W FG L EI G P E FY Sbjct 862 STFLPLKWMAPESI---FNSLYTTLSDVWSFGILLWEIFTLGGTPYPEL--PMNEQFYNA 916 Query 828 -QRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSF 859 +R +R+ +P + ++ + +C + RP F Sbjct 917 IKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPF 951 Score = 39.7 bits (91), Expect = 0.20, Method: Compositional matrix adjust. Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 4/102 (4%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLY-HEH 958 R LG G FG+V + M VAVK LK+ + E+ I+ L H + Sbjct 604 RTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLN 663 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL 1000 ++ G C G + ++ EY G L DYL R+ QL Sbjct 664 VVNLLGACTKGG--PIYIITEYCRYGDLVDYLHRNKHTFLQL 703 >sp|Q9XI96|PERK7_ARATH Proline-rich receptor-like protein kinase PERK7 OS=Arabidopsis thaliana OX=3702 GN=PERK7 PE=2 SV=1 Length=699 Score = 100 bits (248), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 74/207 (36%), Positives = 106/207 (51%), Gaps = 17/207 (8%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 K R LG+G FG V G+ +AVK+LKA G R ++ E++I+ ++H Sbjct 336 FSKDRLLGQGGFGYVHKGILP-----NGKEIAVKSLKAGSGQGERE-FQAEVEIISRVHH 389 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAY 1013 H++ G C + G + L LV E++P +L +L S + L A +G+AY Sbjct 390 RHLVSLVGYCSNAGGQRL-LVYEFLPNDTLEFHLHGKSGTVMDWPTRLKIALGSAKGLAY 448 Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-A 1069 LH IHRD+ A N+LLD++ K+ DFGLAK + + + R G F Y A Sbjct 449 LHEDCHPKIIHRDIKASNILLDHNFEAKVADFGLAKLSQDNNTHVSTRVMG---TFGYLA 505 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096 PE K SDV+SFGV L EL+T Sbjct 506 PEYASSGKLTEKSDVFSFGVMLLELIT 532 Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust. Identities = 48/174 (28%), Positives = 77/174 (44%), Gaps = 26/174 (15%) Query 655 FYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDVWLRRERGHVPMAW--K 711 F ++S+V H HL + G C G + ++V E++ + L+ L + G V M W + Sbjct 377 FQAEVEIISRVHHRHLVSLVGYCSNAGGQRLLVYEFLPNDTLEFHLHGKSGTV-MDWPTR 435 Query 712 MVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + +A A L+YL ++H ++ NILL A K++D GL LS Sbjct 436 LKIALGSAKGLAYLHEDCHPKIIHRDIKASNILLDHNFEA-------KVAD--FGLAKLS 486 Query 769 REERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 ++ +LAPE G L+ D + FG LLE+ G P+ Sbjct 487 QDNNTHVSTRVMGTFGYLAPEYASSG--KLTEKSDVFSFGVMLLEL-ITGRGPV 537 >sp|P35916|VGFR3_HUMAN Vascular endothelial growth factor receptor 3 OS=Homo sapiens OX=9606 GN=FLT4 PE=1 SV=3 Length=1363 Score = 100 bits (250), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 58/175 (33%), Positives = 90/175 (51%), Gaps = 14/175 (8%) Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + + L+ ++ Q+ GM +L ++ IHRDLAARN+LL +VKI DFGLA+ + + +Y Sbjct 1009 LTMEDLVCYSFQVARGMEFLASRKCIHRDLAARNILLSESDVVKICDFGLARDIYKDPDY 1068 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 R + P+ W APE + + + SDVWSFGV L+E+ + +S P + E Sbjct 1069 VR-KGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFS-LGASPYPGVQINE---- 1122 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + L G R+ P+ + +M NCW + RP F L+ IL Sbjct 1123 --------EFCQRLRDGTRMRAPELATPAIRRIMLNCWSGDPKARPAFSELVEIL 1169 Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 43/164 (26%), Positives = 73/164 (45%), Gaps = 22/164 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A + +L ++ +H ++ RNILL+ S +K+ D G+ + V + Sbjct 1020 QVARGMEFLASRKCIHRDLAARNILLSE-------SDVVKICDFGLARDIYKDPDYVRKG 1072 Query 776 -----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 + W+APE + +T D W FG L EI G +P +E+ F QR Sbjct 1073 SARLPLKWMAPESIFDKV--YTTQSDVWSFGVLLWEIFSLGASPYPGVQINEE--FCQRL 1128 Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + R PE + P + + C + +P RP+F ++ L L Sbjct 1129 RDGTRMRAPELATPAIRRIMLNCWSGDPKARPAFSELVEILGDL 1172 >sp|Q9SY91|PBL15_ARATH Probable serine/threonine-protein kinase PBL15 OS=Arabidopsis thaliana OX=3702 GN=PBL15 PE=1 SV=1 Length=424 Score = 98.2 bits (243), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 90/256 (35%), Positives = 122/256 (48%), Gaps = 24/256 (9%) Query 857 PSFRTI-LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD-------LGEGHF 908 PSFR + DL+R + + L + +D F LK I LGEG F Sbjct 54 PSFRRLSFADLSRSSSARINEDLA---QTLGADLVDFQMCELKMITQSFSGNYLLGEGGF 110 Query 909 GKV-SLYCYDPTNDG-TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG-C 965 GKV Y D + VAVK L + HR W E+ L L H +++K G C Sbjct 111 GKVYKGYVDDYLRQSLKAQPVAVKLLDIEGLQGHRE-WLSEVIFLGQLKHPNLVKLIGYC 169 Query 966 CEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQH--YI 1020 CE E+ L+ E++P GSL ++L R S+ A L A +G+A+LH I Sbjct 170 CE---EEERVLIYEFMPRGSLENHLFRRISLSLPWATRLKIAVAAAKGLAFLHDLESPII 226 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 +RD N+LLD+D K+ DFGLAK PEG + + V + APE + Sbjct 227 YRDFKTSNILLDSDFTAKLSDFGLAKMGPEGSKSH-VTTRVMGTYGYAAPEYVSTGHLTT 285 Query 1081 ASDVWSFGVTLYELLT 1096 SDV+S+GV L ELLT Sbjct 286 KSDVYSYGVVLLELLT 301 Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust. Identities = 79/332 (24%), Positives = 131/332 (39%), Gaps = 64/332 (19%) Query 572 RTLNLSQLSFHRVDQKEITQLSH----LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 +TL + F + K ITQ LG+G VY+G + +D L Sbjct 78 QTLGADLVDFQMCELKMITQSFSGNYLLGEGGFGKVYKGYV---------------DDYL 122 Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 R + V +K+LD + + Q+ H +L + G C E +++ Sbjct 123 ---RQSLKAQPVAVKLLDIEGLQGHREWLSEVIFLGQLKHPNLVKLIGYCCEEEERVLIY 179 Query 688 EYVEHGPLDVWL-RRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLAR 744 E++ G L+ L RR +P A ++ +A A L++L + +++ + NILL Sbjct 180 EFMPRGSLENHLFRRISLSLPWATRLKIAVAAAKGLAFLHDLESPIIYRDFKTSNILL-- 237 Query 745 LGLAEGTSPFI-KLSDPGVGLGAL----SREERVERI----PWLAPECLPGGANSLSTAM 795 S F KLSD GL + S+ R+ + APE + G L+T Sbjct 238 ------DSDFTAKLSD--FGLAKMGPEGSKSHVTTRVMGTYGYAAPEYVSTG--HLTTKS 287 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEK------EHFYQRQHRLPEPSCPQLA------- 842 D + +G LLE+ A +SR +++ + + RL P+LA Sbjct 288 DVYSYGVVLLELLTGRRATEKSRPKNQQNIIDWSKPYLTSSRRLRCVMDPRLAGQYSVKA 347 Query 843 -----TLTSQCLTYEPTQRPSFRTILRDLTRL 869 L QC++ P RP ++ L L Sbjct 348 AKDTALLALQCVSPNPKDRPKMLAVVEALESL 379 >sp|O43283|M3K13_HUMAN Mitogen-activated protein kinase kinase kinase 13 OS=Homo sapiens OX=9606 GN=MAP3K13 PE=1 SV=1 Length=966 Score = 100 bits (249), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 83/273 (30%), Positives = 120/273 (44%), Gaps = 39/273 (14%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI--LRTL 954 + +++ LG G G V L + E VA+K ++ + E DI LR L Sbjct 168 ISELQWLGSGAQGAVFLGKF------RAEEVAIKKVRE----------QNETDIKHLRKL 211 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAY 1013 H +II +KG C ++MEY G L + L +LL+ ++ I GM Y Sbjct 212 KHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNY 269 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 LH IHRDL + NVL+ + VKI DFG +K + + + V W APE + Sbjct 270 LHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDK----STKMSFAGTVAWMAPEVI 325 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + D+WSFGV L+ELLT P K ++ I G + Sbjct 326 RNEPVSEKVDIWSFGVVLWELLT-----GEIPYKDVDSSAIIWG---------VGSNSLH 371 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 LP P CP LMK W+++ RP+F + Sbjct 372 LPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTL 404 Score = 65.1 bits (157), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 75/308 (24%), Positives = 120/308 (39%), Gaps = 54/308 (18%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 +A L Q V +EI++L LG G + V+ G+ R E Sbjct 146 GKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAEEVA------------ 193 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 + KV + + DI + ++ H ++ GVC + P ++ Sbjct 194 -------------IKKVREQNETDIKH--------LRKLKHPNIIAFKGVCTQAPCYCII 232 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLAR 744 EY HG L LR R P +++V + +AS ++YL ++H ++ N+L+ Sbjct 233 MEYCAHGQLYEVLRAGRKITP---RLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTH 289 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFG 801 + +K+SD G + ++ + W+APE + +S +D W FG Sbjct 290 -------TDAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFG 340 Query 802 ATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPS 858 L E+ GE P + S LP PS CP L Q +P RPS Sbjct 341 VVLWEL-LTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPS 399 Query 859 FRTILRDL 866 FR L L Sbjct 400 FRQTLMHL 407 >sp|P28028|BRAF_MOUSE Serine/threonine-protein kinase B-raf OS=Mus musculus OX=10090 GN=Braf PE=1 SV=4 Length=751 Score = 100 bits (248), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 78/274 (28%), Positives = 123/274 (45%), Gaps = 35/274 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK L PQ +K E+ +LR H +I+ Sbjct 448 IGSGSFGTV----YKGKWHGD---VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 500 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + L +V ++ SL +L + +L+ A+Q +GM YLHA+ Sbjct 501 FMGYST---KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSI 557 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076 IHRDL + N+ L D VKIGDFGLA ++ + S + W APE ++ + Sbjct 558 IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGS-ILWMAPEVIRMQDKN 616 Query 1077 KFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + SDV++FG+ LYEL+T + + + F+ G ++ +R Sbjct 617 PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVR--------- 667 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 CP + LM C + + RP F ++ Sbjct 668 -----SNCPKAMKRLMAECLKKKRDERPLFPQIL 696 Score = 52.4 bits (124), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 60/254 (24%), Positives = 106/254 (42%), Gaps = 24/254 (9%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G+ G +L V P+ + AF ++ + H ++ G + P+ +VT++ Sbjct 459 GKWHGDVAVKMLNVTAPTPQQLQ-AFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQW 516 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 E L L M + +A+Q A + YL K+++H ++ NI L Sbjct 517 CEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE----- 571 Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802 +K+ D G+ G+ E+ I W+APE + N S D + FG Sbjct 572 --DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGI 629 Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855 L E+ G+ P + + ++ F R + P+ S CP+ + L ++CL + + Sbjct 630 VLYEL-MTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDE 688 Query 856 RPSFRTILRDLTRL 869 RP F IL + L Sbjct 689 RPLFPQILASIELL 702 >sp|Q04982|BRAF_CHICK Serine/threonine-protein kinase B-raf OS=Gallus gallus OX=9031 GN=BRAF PE=1 SV=2 Length=766 Score = 100 bits (248), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 78/274 (28%), Positives = 123/274 (45%), Gaps = 35/274 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK L PQ +K E+ +LR H +I+ Sbjct 463 IGSGSFGTV----YKGKWHGD---VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 515 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + L +V ++ SL +L + +L+ A+Q +GM YLHA+ Sbjct 516 FMGYST---KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSI 572 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076 IHRDL + N+ L D VKIGDFGLA ++ + S + W APE ++ + Sbjct 573 IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGS-ILWMAPEVIRMQDKN 631 Query 1077 KFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + SDV++FG+ LYEL+T + + + F+ G ++ +R Sbjct 632 PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVR--------- 682 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 CP + LM C + + RP F ++ Sbjct 683 -----SNCPKAMKRLMAECLKKKRDERPLFPQIL 711 Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 60/254 (24%), Positives = 106/254 (42%), Gaps = 24/254 (9%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G+ G +L V P+ + AF ++ + H ++ G + P+ +VT++ Sbjct 474 GKWHGDVAVKMLNVTAPTPQQLQ-AFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQW 531 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 E L L M + +A+Q A + YL K+++H ++ NI L Sbjct 532 CEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE----- 586 Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802 +K+ D G+ G+ E+ I W+APE + N S D + FG Sbjct 587 --DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGI 644 Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855 L E+ G+ P + + ++ F R + P+ S CP+ + L ++CL + + Sbjct 645 VLYEL-MTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDE 703 Query 856 RPSFRTILRDLTRL 869 RP F IL + L Sbjct 704 RPLFPQILASIELL 717 >sp|Q8T2I8|SEPA_DICDI Serine/threonine-protein kinase sepA OS=Dictyostelium discoideum OX=44689 GN=sepA PE=2 SV=1 Length=1167 Score = 100 bits (250), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 63/196 (32%), Positives = 102/196 (52%), Gaps = 13/196 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIK 961 +G+G FG V Y + G+ VA+K + P+ + G EID+L+ L H +I+K Sbjct 24 IGKGGFGTV----YQGLDIEDGDFVAIKQINLTKIPKDQLQGIMNEIDLLKNLNHANIVK 79 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL-LFAQQICEGMAYLHAQHYI 1020 Y + + +L +V+EYV GSL + + L+ ++ +Q+ EG+ YLH Q + Sbjct 80 YIKYVKTKD--NLYIVLEYVENGSLSGIIKKFGKFPETLVCVYIRQVLEGLVYLHEQGVV 137 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ N+L + +K+ DFG+A + V +P +W APE ++ Sbjct 138 HRDIKGANILTTKEGKIKLADFGVATKFDDTSAAAVV----GTP-YWMAPEIIELNGATT 192 Query 1081 ASDVWSFGVTLYELLT 1096 SD+WS G T+ ELLT Sbjct 193 KSDIWSVGCTVIELLT 208 Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 56/192 (29%), Positives = 84/192 (44%), Gaps = 16/192 (8%) Query 678 VRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736 V+ +N+ +V EYVE+G L +++ G P V +Q+ L YL + +VH ++ Sbjct 84 VKTKDNLYIVLEYVENGSLSGIIKK-FGKFPETLVCVYIRQVLEGLVYLHEQGVVHRDIK 142 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTA 794 G NIL + G IKL+D GV S V W+APE + N +T Sbjct 143 GANILTTKEGK-------IKLADFGVATKFDDTSAAAVVGTPYWMAPEIIE--LNGATTK 193 Query 795 MDKWGFGATLLEICFDGEAPLQS--RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYE 852 D W G T++E+ G P + P+ LPE P L QC + Sbjct 194 SDIWSVGCTVIEL-LTGSPPYYDLGQMPALFRIVQDDCPPLPEGISPPLKDWLMQCFQKD 252 Query 853 PTQRPSFRTILR 864 P R S + +L+ Sbjct 253 PNLRISAQKLLK 264 >sp|P34908|BRAF_COTJA Serine/threonine-protein kinase B-raf OS=Coturnix japonica OX=93934 GN=BRAF PE=2 SV=1 Length=807 Score = 100 bits (248), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 78/274 (28%), Positives = 123/274 (45%), Gaps = 35/274 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK L PQ +K E+ +LR H +I+ Sbjct 503 IGSGSFGTV----YKGKWHGD---VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILL 555 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + L +V ++ SL +L + +L+ A+Q +GM YLHA+ Sbjct 556 FMGYST---KPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSI 612 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076 IHRDL + N+ L D VKIGDFGLA ++ + S + W APE ++ + Sbjct 613 IHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGS-ILWMAPEVIRMQDKN 671 Query 1077 KFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + SDV++FG+ LYEL+T + + + F+ G ++ +R Sbjct 672 PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVR--------- 722 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 CP + LM C + + RP F ++ Sbjct 723 -----SNCPKAMKRLMAECLKKKRDERPLFPQIL 751 Score = 52.0 bits (123), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 60/254 (24%), Positives = 106/254 (42%), Gaps = 24/254 (9%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G+ G +L V P+ + AF ++ + H ++ G + P+ +VT++ Sbjct 514 GKWHGDVAVKMLNVTAPTPQQLQ-AFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQW 571 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 E L L M + +A+Q A + YL K+++H ++ NI L Sbjct 572 CEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE----- 626 Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802 +K+ D G+ G+ E+ I W+APE + N S D + FG Sbjct 627 --DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGI 684 Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855 L E+ G+ P + + ++ F R + P+ S CP+ + L ++CL + + Sbjct 685 VLYEL-MTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDE 743 Query 856 RPSFRTILRDLTRL 869 RP F IL + L Sbjct 744 RPLFPQILASIELL 757 >sp|Q9C6K9|LRL11_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 1.1 OS=Arabidopsis thaliana OX=3702 GN=LRK10L-1.1 PE=2 SV=1 Length=629 Score = 99.8 bits (247), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 86/293 (29%), Positives = 135/293 (46%), Gaps = 23/293 (8%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 K R LG+G FG V Y DG VAVK L + + + EI+IL L+H Sbjct 291 FSKDRLLGDGGFGTVY---YGKVRDG--REVAVKRL-YEHNYRRLEQFMNEIEILTRLHH 344 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEG 1010 ++++ GC + + L LV E++P G++ D+L + + + L A + Sbjct 345 KNLVSLYGCTSRRS-RELLLVYEFIPNGTVADHLYGENTPHQGFLTWSMRLSIAIETASA 403 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 +AYLHA IHRD+ N+LLD + VK+ DFGL++ +P + G + P Sbjct 404 LAYLHASDIIHRDVKTTNILLDRNFGVKVADFGLSRLLPSDVTHVSTAPQGTPG--YVDP 461 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 E + Y SDV+SFGV L EL++ D S+ L + I + Q EL Sbjct 462 EYHRCYHLTDKSDVYSFGVVLVELISSKPAVDISRCKSEINLSSLAINKIQNHATH--EL 519 Query 1128 LERGERLPRPD---KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 +++ + K V L C + + + RPT E ++ LK + + Q Sbjct 520 IDQNLGYATNEGVRKMTTMVAELAFQCLQQDNTMRPTMEQVVHELKGIQNEEQ 572 Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 58/248 (23%), Positives = 105/248 (42%), Gaps = 43/248 (17%) Query 655 FYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDVWLRRE----RGHVPMA 709 F +++++ H +L ++G R E ++V E++ +G + L E +G + + Sbjct 332 FMNEIEILTRLHHKNLVSLYGCTSRRSRELLLVYEFIPNGTVADHLYGENTPHQGFLTWS 391 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 ++ +A + ASAL+YL +++H +V NILL R + +K++D G+ S Sbjct 392 MRLSIAIETASALAYLHASDIIHRDVKTTNILLDR-------NFGVKVADFGLSRLLPSD 444 Query 770 EERVERIPWLAPECLPGGAN-------SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 V AP+ PG + L+ D + FG L+E+ A SR SE Sbjct 445 VTHVS----TAPQGTPGYVDPEYHRCYHLTDKSDVYSFGVVLVELISSKPAVDISRCKSE 500 Query 823 --------KEHFYQRQHRLPEPS------------CPQLATLTSQCLTYEPTQRPSFRTI 862 + H L + + +A L QCL + T RP+ + Sbjct 501 INLSSLAINKIQNHATHELIDQNLGYATNEGVRKMTTMVAELAFQCLQQDNTMRPTMEQV 560 Query 863 LRDLTRLQ 870 + +L +Q Sbjct 561 VHELKGIQ 568 >sp|Q5R8X7|M3K13_PONAB Mitogen-activated protein kinase kinase kinase 13 OS=Pongo abelii OX=9601 GN=MAP3K13 PE=2 SV=1 Length=966 Score = 100 bits (249), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 83/273 (30%), Positives = 120/273 (44%), Gaps = 39/273 (14%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI--LRTL 954 + +++ LG G G V L + E VA+K ++ + E DI LR L Sbjct 168 ISELQWLGSGAQGAVFLGKF------RAEEVAIKKVRE----------QNETDIKHLRKL 211 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAY 1013 H +II +KG C ++MEY G L + L +LL+ ++ I GM Y Sbjct 212 KHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNY 269 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 LH IHRDL + NVL+ + VKI DFG +K + + + V W APE + Sbjct 270 LHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDK----STKMSFAGTVAWLAPEVI 325 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + D+WSFGV L+ELLT P K ++ I G + Sbjct 326 RNEPVSEKVDIWSFGVVLWELLT-----GEIPYKDVDSSAIIWG---------VGSNSLH 371 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 LP P CP LMK W+++ RP+F + Sbjct 372 LPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTL 404 Score = 65.9 bits (159), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 75/299 (25%), Positives = 118/299 (39%), Gaps = 54/299 (18%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L Q V +EI++L LG G + V+ G+ R E Sbjct 155 LQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAEEVA--------------------- 193 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 + KV + + DI + ++ H ++ GVC + P ++ EY HG L Sbjct 194 ----IKKVREQNETDI--------KHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQL 241 Query 696 DVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 LR R P +++V + +AS ++YL ++H ++ N+L+ + Sbjct 242 YEVLRAGRKITP---RLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTH-------TD 291 Query 754 FIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +K+SD G + ++ + WLAPE + +S +D W FG L E+ Sbjct 292 AVKISDFGTSKELSDKSTKMSFAGTVAWLAPEVIRN--EPVSEKVDIWSFGVVLWEL-LT 348 Query 811 GEAPLQSRSPSEKE-HFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866 GE P + S LP PS CP L Q +P RPSFR L L Sbjct 349 GEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHL 407 >sp|C0LGQ7|Y4245_ARATH Probable LRR receptor-like serine/threonine-protein kinase At4g20450 OS=Arabidopsis thaliana OX=3702 GN=At4g20450 PE=1 SV=1 Length=898 Score = 100 bits (249), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 72/203 (35%), Positives = 108/203 (53%), Gaps = 16/203 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LGEG FG V + ND E VAVK L ++ Q +K E+D+L ++H +++ Sbjct 595 RPLGEGGFGVV---YHGNVNDN--EQVAVKVL-SESSAQGYKQFKAEVDLLLRVHHINLV 648 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHA 1016 G C D+G+ L L+ EY+ G+L+ +L R + L A + +G+ YLH Sbjct 649 TLVGYC-DEGQH-LVLIYEYMSNGNLKQHLSGENSRSPLSWENRLRIAAETAQGLEYLHI 706 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRD+ + N+LLDN+ K+GDFGL+++ P G E + SP + PE Sbjct 707 GCKPPMIHRDIKSMNILLDNNFQAKLGDFGLSRSFPVGSETHVSTNVAGSPGY-LDPEYY 765 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 + SDV+SFGV L E++T Sbjct 766 RTNWLTEKSDVFSFGVVLLEIIT 788 Score = 52.4 bits (124), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 64/237 (27%), Positives = 97/237 (41%), Gaps = 35/237 (15%) Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660 TN +E L G G G ++D + +V +KVL S F Sbjct 590 TNNFERPLGEGGFGVVYHGNVNDNE------------QVAVKVLSESSAQGYKQFKAEVD 637 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQL 718 L+ +V H +L + G C G +++ EY+ +G L L E P++W ++ +A + Sbjct 638 LLLRVHHINLVTLVGYCDEGQHLVLIYEYMSNGNLKQHLSGENSRSPLSWENRLRIAAET 697 Query 719 ASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGALSR-E 770 A L YL ++H ++ NILL A KL D G+ +G+ + Sbjct 698 AQGLEYLHIGCKPPMIHRDIKSMNILLDNNFQA-------KLGDFGLSRSFPVGSETHVS 750 Query 771 ERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 V P +L PE N L+ D + FG LLEI Q+R EK H Sbjct 751 TNVAGSPGYLDPEYYR--TNWLTEKSDVFSFGVVLLEIITSQPVIDQTR---EKSHI 802 >sp|Q9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 OS=Homo sapiens OX=9606 GN=STK24 PE=1 SV=1 Length=443 Score = 98.2 bits (243), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 77/274 (28%), Positives = 125/274 (46%), Gaps = 36/274 (13%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 K+ +G+G FG+V + ++ T ++VA+K + + +QEI +L + Sbjct 38 KLEKIGKGSFGEV----FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPY 93 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 + KY G + L ++MEY+ GS D L + Q+ ++I +G+ YLH++ Sbjct 94 VTKYYGSY--LKDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEK 151 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ A NVLL VK+ DFG+A + + R FW APE +K+ + Sbjct 152 KIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQ---IKRNTFVGTPFWMAPEVIKQSAY 208 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 +D+WS G+T EL + PP L M VL L +P+ + Sbjct 209 DSKADIWSLGITAIEL-----ARGEPPHSELH-------PMKVLFL---------IPKNN 247 Query 1139 KCPCE------VYHLMKNCWETEASFRPTFENLI 1166 E + ++ C E SFRPT + L+ Sbjct 248 PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELL 281 Score = 54.7 bits (130), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 74/330 (22%), Positives = 133/330 (40%), Gaps = 67/330 (20%) Query 544 CFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603 + RR LP PG ++NL +A P L T+L +G+G+ V Sbjct 11 ALNKRRATLPHPGGSTNL------KADPEEL--------------FTKLEKIGKGSFGEV 50 Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLM 662 ++G +D+ R Q++ V +K++D D + +++ Sbjct 51 FKG--------------IDN---------RTQKV-VAIKIIDLEEAEDEIEDIQQEITVL 86 Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWLRRERGHVPMAWKMVVAQQLASA 721 SQ ++ +G ++ + ++ EY+ G LD+ E G + + +++ Sbjct 87 SQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL---EPGPLDETQIATILREILKG 143 Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS-----REERVERI 776 L YL ++ +H ++ N+LL+ G +KL+D GV G L+ R V Sbjct 144 LDYLHSEKKIHRDIKAANVLLSEHG-------EVKLADFGVA-GQLTDTQIKRNTFVGTP 195 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH--RLP 834 W+APE + A + D W G T +E+ GE P P + + + L Sbjct 196 FWMAPEVIKQSA--YDSKADIWSLGITAIELA-RGEPPHSELHPMKVLFLIPKNNPPTLE 252 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 L CL EP+ RP+ + +L+ Sbjct 253 GNYSKPLKEFVEACLNKEPSFRPTAKELLK 282 >sp|Q80YP0|CDK3_MOUSE Cyclin-dependent kinase 3 OS=Mus musculus OX=10090 GN=Cdk3 PE=1 SV=3 Length=304 Score = 95.9 bits (237), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 69/205 (34%), Positives = 103/205 (50%), Gaps = 15/205 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955 +K+ +GEG +G V Y N TG++VA+K ++ D + S +EI +L+ L Sbjct 4 FQKVEKIGEGTYGVV----YKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKELK 59 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013 H +IIK EK L +V E++ L D P + L + + Q+ EG+++ Sbjct 60 HPNIIKLLDVVHR--EKKLYMVFEFLTQDLKRHMDSSPTSELPLPVVKSYLAQLLEGVSF 117 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072 H+ IHRDL +N+LLD +K+ DFGLA+A Y + WY APE Sbjct 118 CHSHRVIHRDLKPQNLLLDGLGAIKLADFGLARAFGVPLRTY----THEVVTLWYRAPEI 173 Query 1073 LKEYKFY-YASDVWSFGVTLYELLT 1096 L KFY A D+WS G E++T Sbjct 174 LLGSKFYSTAVDIWSIGCIFAEMVT 198 Score = 42.0 bits (97), Expect = 0.027, Method: Compositional matrix adjust. Identities = 67/307 (22%), Positives = 116/307 (38%), Gaps = 65/307 (21%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-LDPSHH 649 ++ +G+GT VY+ R +V G +L + K+ LD Sbjct 6 KVEKIGEGTYGVVYKARNKVTG-----------------------QLVALKKIRLDLEAE 42 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 + SL+ ++ H ++ + V R + MV E++ +P+ Sbjct 43 GVPSTAVREISLLKELKHPNIIKLLDVVHREKKLYMVFEFLTQDLKRHMDSSPTSELPLP 102 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLG 765 QL +S+ + ++H ++ +N+LL LG IKL+D G+ G+ Sbjct 103 VVKSYLAQLLEGVSFCHSHRVIHRDLKPQNLLLDGLGA-------IKLADFGLARAFGVP 155 Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEA------- 813 + V + + APE L G+ STA+D W G E+ F G++ Sbjct 156 LRTYTHEVVTLWYRAPEILL-GSKFYSTAVDIWSIGCIFAEMVTGKALFPGDSEIDQLFR 214 Query 814 -------------PLQSRSPSEKEHFYQRQHRLPEPSCPQLA----TLTSQCLTYEPTQR 856 P S+ P + F + + E P L L + L Y+P+QR Sbjct 215 IFRTLGTPSEATWPGVSQMPDYQSSFPKWSRKGLEEIVPSLGPEGKDLLLRLLQYDPSQR 274 Query 857 PSFRTIL 863 S +T L Sbjct 275 ISAKTAL 281 >sp|Q99N57|RAF1_MOUSE RAF proto-oncogene serine/threonine-protein kinase OS=Mus musculus OX=10090 GN=Raf1 PE=1 SV=2 Length=648 Score = 99.8 bits (247), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 68/199 (34%), Positives = 102/199 (51%), Gaps = 17/199 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+ Sbjct 355 IGSGSFGTV----YKGKWHGD---VAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILL 407 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ Sbjct 408 FMGY---MTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNI 464 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076 IHRD+ + N+ L VKIGDFGLA +V + S V W APE ++ + Sbjct 465 IHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS-VLWMAPEVIRMQDDN 523 Query 1077 KFYYASDVWSFGVTLYELL 1095 F + SDV+S+G+ LYEL+ Sbjct 524 PFSFQSDVYSYGIVLYELM 542 Score = 62.8 bits (151), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 70/286 (24%), Positives = 127/286 (44%), Gaps = 32/286 (11%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTE 688 G+ G +LKV+DP+ + AF +++ + H ++ G + +N+ +VT+ Sbjct 366 GKWHGDVAVKILKVVDPTPEQLQ-AFRNEVAVLRKTRHVNILLFMGYMTK--DNLAIVTQ 422 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + E L L + M + +A+Q A + YL KN++H ++ NI L Sbjct 423 WCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIF-----LH 477 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFG 801 EG + +K+ D G+ G+ E+ + W+APE + N S D + +G Sbjct 478 EGLT--VKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYG 535 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPT 854 L E+ GE P + ++ F R + P+ S CP+ + L + C+ Sbjct 536 IVLYEL-MAGELPYAHINNRDQIIFMVGRGYASPDLSRLYKNCPKAMKRLVADCVKKVKE 594 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 +RP F IL + LQ H+L + + AS+P++ + + I Sbjct 595 ERPLFPQILSSIELLQ-HSLPKI-----NRSASEPSLHRAAHTEDI 634 >sp|Q84M95|PBL28_ARATH Probable serine/threonine-protein kinase PBL28 OS=Arabidopsis thaliana OX=3702 GN=PBL28 PE=2 SV=1 Length=375 Score = 97.1 bits (240), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 83/228 (36%), Positives = 116/228 (51%), Gaps = 33/228 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL------KADCGPQHRSGWKQEIDILRTLYH 956 LG+G FG+V Y T TGE+VA+K + KAD + R E+DIL L H Sbjct 82 LGKGGFGRV----YQGTLK-TGEVVAIKKMDLPTFKKADGEREFRV----EVDILSRLDH 132 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGM 1011 +++ G C D K LV EY+ G+L+D+L + I A++ L A +G+ Sbjct 133 PNLVSLIGYCADG--KHRFLVYEYMQNGNLQDHL--NGIKEAKISWPIRLRIALGAAKGL 188 Query 1012 AYLHAQH-----YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 AYLH+ +HRD + NVLLD++ KI DFGLAK +PEG + V Sbjct 189 AYLHSSSSVGIPIVHRDFKSTNVLLDSNYNAKISDFGLAKLMPEGKDTC-VTARVLGTFG 247 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLT---HCDSSQSPPTKFLEL 1111 ++ PE K SD+++FGV L ELLT D +Q P + L L Sbjct 248 YFDPEYTSTGKLTLQSDIYAFGVVLLELLTGRRAVDLTQGPNEQNLVL 295 Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 70/304 (23%), Positives = 120/304 (39%), Gaps = 64/304 (21%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LG+G VY+G L+ +G+ K D P D +E RV + +L Sbjct 82 LGKGGFGRVYQGTLK---TGEVVAIKKMDL-PTFKKADGEREFRVEVDIL---------- 127 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 S++ H +L + G C G +V EY+++G L L + ++W ++ Sbjct 128 --------SRLDHPNLVSLIGYCADGKHRFLVYEYMQNGNLQDHLNGIK-EAKISWPIRL 178 Query 713 VVAQQLASALSYLENKN-----LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----- 762 +A A L+YL + + +VH + N+LL ++ K+SD G+ Sbjct 179 RIALGAAKGLAYLHSSSSVGIPIVHRDFKSTNVLL-------DSNYNAKISDFGLAKLMP 231 Query 763 -GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 G + + PE G +L + D + FG LLE+ A ++ P+ Sbjct 232 EGKDTCVTARVLGTFGYFDPEYTSTGKLTLQS--DIYAFGVVLLELLTGRRAVDLTQGPN 289 Query 822 EKEHFYQRQH--------------RLPEPS-----CPQLATLTSQCLTYEPTQRPSFRTI 862 E+ Q ++ LP S A L S+C+ E +RPS Sbjct 290 EQNLVLQVRNILNDRKKLRKVIDVELPRNSYSMEAITMFADLASRCIRIESKERPSVMDC 349 Query 863 LRDL 866 +++L Sbjct 350 VKEL 353 >sp|B0LT89|STK24_RAT Serine/threonine-protein kinase 24 OS=Rattus norvegicus OX=10116 GN=Stk24 PE=2 SV=1 Length=431 Score = 97.8 bits (242), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 77/274 (28%), Positives = 125/274 (46%), Gaps = 36/274 (13%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 K+ +G+G FG+V + ++ T ++VA+K + + +QEI +L + Sbjct 26 KLEKIGKGSFGEV----FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPY 81 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 + KY G + L ++MEY+ GS D L + Q+ ++I +G+ YLH++ Sbjct 82 VTKYYGSY--LKDTKLWIIMEYLGGGSALDLLEPGPLDEIQIATILREILKGLDYLHSEK 139 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ A NVLL VK+ DFG+A + + R FW APE +K+ + Sbjct 140 KIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQ---IKRNTFVGTPFWMAPEVIKQSAY 196 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 +D+WS G+T EL + PP L M VL L +P+ + Sbjct 197 DSKADIWSLGITAIEL-----AKGEPPHSELH-------PMKVLFL---------IPKNN 235 Query 1139 KCPCE------VYHLMKNCWETEASFRPTFENLI 1166 E + ++ C E SFRPT + L+ Sbjct 236 PPTLEGSYSRPLKEFVEACLNKEPSFRPTAKELL 269 Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 68/305 (22%), Positives = 127/305 (42%), Gaps = 48/305 (16%) Query 570 SPRTLNLSQLSFHRVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 SP L + + D +E+ T+L +G+G+ V++G +D+ Sbjct 4 SPVQSGLPGMQTLKADPEELFTKLEKIGKGSFGEVFKG--------------IDN----- 44 Query 629 PGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 R Q++ V +K++D D + +++SQ ++ +G ++ + ++ Sbjct 45 ----RTQKV-VAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIM 99 Query 688 EYVEHGP-LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 EY+ G LD+ E G + + +++ L YL ++ +H ++ N+LL+ G Sbjct 100 EYLGGGSALDLL---EPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHG 156 Query 747 LAEGTSPFIKLSDPGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 +KL+D GV G L+ R V W+APE + A + D W G Sbjct 157 -------EVKLADFGVA-GQLTDTQIKRNTFVGTPFWMAPEVIKQSA--YDSKADIWSLG 206 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSF 859 T +E+ GE P P + + + L L CL EP+ RP+ Sbjct 207 ITAIELA-KGEPPHSELHPMKVLFLIPKNNPPTLEGSYSRPLKEFVEACLNKEPSFRPTA 265 Query 860 RTILR 864 + +L+ Sbjct 266 KELLK 270 >sp|Q3SWY6|STK25_BOVIN Serine/threonine-protein kinase 25 OS=Bos taurus OX=9913 GN=STK25 PE=2 SV=1 Length=426 Score = 97.8 bits (242), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 77/274 (28%), Positives = 124/274 (45%), Gaps = 36/274 (13%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 K+ +G+G FG+V Y ++ T E+VA+K + + +QEI +L + Sbjct 22 KLDRIGKGSFGEV----YKGIDNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPY 77 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I +Y G + L ++MEY+ GS D L + + ++I +G+ YLH++ Sbjct 78 ITRYFGSYLKSTK--LWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSER 135 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ A NVLL VK+ DFG+A + + R FW APE +K+ + Sbjct 136 KIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQ---IKRNTFVGTPFWMAPEVIKQSAY 192 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 + +D+WS G+T EL + PP L M VL L +P+ Sbjct 193 DFKADIWSLGITAIEL-----AKGEPPNSDLH-------PMRVLFL---------IPKNS 231 Query 1139 KCPCEVYH------LMKNCWETEASFRPTFENLI 1166 E +H ++ C + FRPT + L+ Sbjct 232 PPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELL 265 Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 66/298 (22%), Positives = 124/298 (42%), Gaps = 60/298 (20%) Query 583 RVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 RVD +E+ T+L +G+G+ VY+G +D+ R +E+ V + Sbjct 13 RVDPEELFTKLDRIGKGSFGEVYKG--------------IDN---------RTKEV-VAI 48 Query 642 KVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWL 699 K++D D + +++SQ ++ G ++ + ++ EY+ G LD+ Sbjct 49 KIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLL- 107 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + G + + + +++ L YL ++ +H ++ N+LL+ G +KL+D Sbjct 108 --KPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQG-------DVKLAD 158 Query 760 PGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 GV G L+ R V W+APE + A D W G T +E+ Sbjct 159 FGVA-GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKA--DIWSLGITAIELA------ 209 Query 815 LQSRSPSEKEHFYQRQHRLPEPSCPQL--------ATLTSQCLTYEPTQRPSFRTILR 864 + P+ H + +P+ S P L CL +P RP+ + +L+ Sbjct 210 -KGEPPNSDLHPMRVLFLIPKNSPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLK 266 >sp|Q99KH8|STK24_MOUSE Serine/threonine-protein kinase 24 OS=Mus musculus OX=10090 GN=Stk24 PE=1 SV=1 Length=431 Score = 97.8 bits (242), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 77/274 (28%), Positives = 125/274 (46%), Gaps = 36/274 (13%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 K+ +G+G FG+V + ++ T ++VA+K + + +QEI +L + Sbjct 26 KLEKIGKGSFGEV----FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPY 81 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 + KY G + L ++MEY+ GS D L + Q+ ++I +G+ YLH++ Sbjct 82 VTKYYGSY--LKDTKLWIIMEYLGGGSALDLLEPGPLDEIQIATILREILKGLDYLHSEK 139 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ A NVLL VK+ DFG+A + + R FW APE +K+ + Sbjct 140 KIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQ---IKRNTFVGTPFWMAPEVIKQSAY 196 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 +D+WS G+T EL + PP L M VL L +P+ + Sbjct 197 DSKADIWSLGITAIEL-----AKGEPPHSELH-------PMKVLFL---------IPKNN 235 Query 1139 KCPCE------VYHLMKNCWETEASFRPTFENLI 1166 E + ++ C E SFRPT + L+ Sbjct 236 PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELL 269 Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 56/244 (23%), Positives = 102/244 (42%), Gaps = 23/244 (9%) Query 630 GRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 G D + V +K++D D + +++SQ ++ +G ++ + ++ E Sbjct 41 GIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIME 100 Query 689 YVEHGP-LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 Y+ G LD+ E G + + +++ L YL ++ +H ++ N+LL+ G Sbjct 101 YLGGGSALDLL---EPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHG- 156 Query 748 AEGTSPFIKLSDPGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 +KL+D GV G L+ R V W+APE + A + D W G Sbjct 157 ------EVKLADFGVA-GQLTDTQIKRNTFVGTPFWMAPEVIKQSA--YDSKADIWSLGI 207 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 T +E+ GE P P + + + L L CL EP+ RP+ + Sbjct 208 TAIELA-KGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAK 266 Query 861 TILR 864 +L+ Sbjct 267 ELLK 270 >sp|Q869X3|Y9851_DICDI Probable serine/threonine-protein kinase DDB_G0275165 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0275165 PE=3 SV=1 Length=921 Score = 100 bits (248), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 83/278 (30%), Positives = 133/278 (48%), Gaps = 33/278 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWK---QEIDILRTLYHEH 958 +G G FGKV + G+ + +K + +D P K +EI L+ L H + Sbjct 29 IGSGGFGKVYQGVLN------GKEIGIKKITISDNDPNRDILLKFLEREIYTLKMLSHPN 82 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--FAQQICEGMAYLHA 1016 +IK+ G E E+SL L+ E V G L Y+ SI + L A+ I MAYLH Sbjct 83 VIKFYGIAE--KERSLFLLTELVSGGDLHWYIKNKSIDITWKLKVKIARDIAASMAYLHE 140 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRDL + N+L+ + ++K+ D GLA+ + + + D W APE L Sbjct 141 NGVIHRDLKSTNLLVAENWVIKVCDMGLARKMDKSEKSKMTICGTDD---WMAPEVLIGE 197 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 ++ + DV+SFG+ L EL+T + + P E +G+ Q L+++ Sbjct 198 EYDASCDVFSFGMVLIELITRENLT---PRIRNEDLGVDQK----FFLSKV--------- 241 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 P CP E+ L+ C + S RP+ N++ +L+ + E Sbjct 242 PADCPKELLRLVSECCKVAPSGRPSASNILGLLEYILE 279 Score = 61.6 bits (148), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 69/286 (24%), Positives = 123/286 (43%), Gaps = 40/286 (14%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 D+ + LS +G G VY+G L G++ G + ++ + Sbjct 19 DEIKFDPLSIIGSGGFGKVYQGVLN--------------------GKEIGIK-KITISDN 57 Query 645 DPSHHDIALAFYE-TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 DP + DI L F E + +SH ++ +G+ + ++TE V G L +++ + Sbjct 58 DP-NRDILLKFLEREIYTLKMLSHPNVIKFYGIAEKERSLFLLTELVSGGDLHWYIKNKS 116 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + K+ +A+ +A++++YL ++H ++ N+L+A + IK+ D G+ Sbjct 117 IDITWKLKVKIARDIAASMAYLHENGVIHRDLKSTNLLVAENWV-------IKVCDMGLA 169 Query 764 LGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 E+ I W+APE L G + D + FG L+E+ L R Sbjct 170 RKMDKSEKSKMTICGTDDWMAPEVLIG--EEYDASCDVFSFGMVLIELI--TRENLTPRI 225 Query 820 PSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTIL 863 +E Q+ P+ CP +L L S+C P+ RPS IL Sbjct 226 RNEDLGVDQKFFLSKVPADCPKELLRLVSECCKVAPSGRPSASNIL 271 >sp|Q9XI87|VIK_ARATH Serine/threonine-protein kinase VIK OS=Arabidopsis thaliana OX=3702 GN=VIK PE=1 SV=1 Length=438 Score = 97.8 bits (242), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 84/282 (30%), Positives = 133/282 (47%), Gaps = 34/282 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHII 960 +G+G FG++ + G VAVK + ++ E+D+L L H +I+ Sbjct 168 IGKGSFGEIVKAYW------RGTPVAVKRILPSLSDDRLVIQDFRHEVDLLVKLRHPNIV 221 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 ++ G ++ K L L+ EY+ G L YL + + + FA I GM YLH + Sbjct 222 QFLGAVTER--KPLMLITEYLRGGDLHQYLKEKGGLTPTTAVNFALDIARGMTYLHNEPN 279 Query 1018 HYIHRDLAARNVLLDNDRL--VKIGDFGLAK--AVPEGHEYYRVREDGDSPVFWY-APEC 1072 IHRDL RNVLL N +K+GDFGL+K V H+ Y++ G++ + Y APE Sbjct 280 VIIHRDLKPRNVLLVNSSADHLKVGDFGLSKLIKVQNSHDVYKMT--GETGSYRYMAPEV 337 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 K ++ DV+SF + LYE+L PP E A+ R T Sbjct 338 FKHRRYDKKVDVFSFAMILYEML-----EGEPPFANHEPYEAAKHVSDGHRPTF------ 386 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 R C ++ L+ CW+ + + RP+F +++ L+ + E Sbjct 387 ---RSKGCTPDLRELIVKCWDADMNQRPSFLDILKRLEKIKE 425 Score = 60.1 bits (144), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 63/249 (25%), Positives = 109/249 (44%), Gaps = 27/249 (11%) Query 639 VVLKVLDPSHHDIALA---FYETASLMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGP 694 V +K + PS D L F L+ ++ H ++ F+ V R P +++TEY+ G Sbjct 186 VAVKRILPSLSDDRLVIQDFRHEVDLLVKLRHPNIVQFLGAVTERKPL-MLITEYLRGGD 244 Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENK--NLVHGNVCGRNILLARLGLAEGTS 752 L +L+ + G P + A +A ++YL N+ ++H ++ RN+LL ++ Sbjct 245 LHQYLKEKGGLTPTT-AVNFALDIARGMTYLHNEPNVIIHRDLKPRNVLLV-----NSSA 298 Query 753 PFIKLSDPGVG-LGALSREERVERIP-------WLAPECLPGGANSLSTAMDKWGFGATL 804 +K+ D G+ L + V ++ ++APE +D + F L Sbjct 299 DHLKVGDFGLSKLIKVQNSHDVYKMTGETGSYRYMAPEVFK--HRRYDKKVDVFSFAMIL 356 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSC-PQLATLTSQCLTYEPTQRPSFRT 861 E+ +GE P + P E HR C P L L +C + QRPSF Sbjct 357 YEM-LEGEPPFANHEPYEAAKHVSDGHRPTFRSKGCTPDLRELIVKCWDADMNQRPSFLD 415 Query 862 ILRDLTRLQ 870 IL+ L +++ Sbjct 416 ILKRLEKIK 424 >sp|F1NBT0|STK10_CHICK Serine/threonine-protein kinase 10 OS=Gallus gallus OX=9031 GN=STK10 PE=3 SV=2 Length=969 Score = 100 bits (248), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 68/201 (34%), Positives = 106/201 (53%), Gaps = 19/201 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +LG+G FGKV Y N TG + A K ++ + EI+IL T H HI+K Sbjct 41 ELGDGAFGKV----YKAKNKETGALAAAKVIETK-NEDELEDYMVEIEILATCDHPHIVK 95 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019 G +G+ L +++E+ P G++ + GL Q+ + +Q+ E + YLH++ Sbjct 96 LLGAFYWEGK--LWIMIEFCPGGAVDATMLELDRGLTEPQIQVICRQMLEALHYLHSKKI 153 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVFWYAP-----ECL 1073 IHRDL A NVLL D +K+ DFG+ AK V + + R+ +W AP E + Sbjct 154 IHRDLKAGNVLLTQDGDIKLADFGVSAKNV----KTLQKRDSFIGTPYWMAPEVVMCETM 209 Query 1074 KEYKFYYASDVWSFGVTLYEL 1094 K+ + Y +D+WS G+TL E+ Sbjct 210 KDTPYDYKADIWSLGITLIEM 230 Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust. Identities = 46/176 (26%), Positives = 77/176 (44%), Gaps = 18/176 (10%) Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV-RGPENIMVTEYVEHGPLD-VWL 699 KV++ + D + +++ H H+ + G G IM+ E+ G +D L Sbjct 65 KVIETKNEDELEDYMVEIEILATCDHPHIVKLLGAFYWEGKLWIMI-EFCPGGAVDATML 123 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 +RG + V+ +Q+ AL YL +K ++H ++ N+LL + G IKL+D Sbjct 124 ELDRG-LTEPQIQVICRQMLEALHYLHSKKIIHRDLKAGNVLLTQDG-------DIKLAD 175 Query 760 PGV---GLGALSREERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808 GV + L + + P W+APE C D W G TL+E+ Sbjct 176 FGVSAKNVKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMA 231 >sp|G5ED65|VER1_CAEEL Protein ver-1 OS=Caenorhabditis elegans OX=6239 GN=ver-1 PE=2 SV=1 Length=1083 Score = 100 bits (248), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 77/297 (26%), Positives = 125/297 (42%), Gaps = 55/297 (19%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 FHK L+ + +G GHFG V GT +VAVK+ + +E+ ++ Sbjct 798 FHKDSLEILEPIGSGHFGVVRRGILK----GTKTVVAVKSSSYRSSIGFQKVIVEELKLM 853 Query 952 RTL-YHEHIIKYKGC-CEDQGEKSLQLVMEYVPLGSLRDYLPR----------------- 992 + H +++ G ++ L ++MEY+ G+LRD+L + Sbjct 854 SAIPKHPNVLALVGAITKNLRHGELYILMEYIDGGNLRDFLQQRRNVFIDELHDNFDENI 913 Query 993 -------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +S+ L+ A QI GM +L +H +L R VL+ + ++I D+G+ Sbjct 914 PLIRPDFNSLSTTDLVGIAHQIANGMEWLGNVPCVHGNLCCRKVLISKTKTIRITDYGVG 973 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 R+ S + W APE ++ F SDVWSFG+ LYE+ T Sbjct 974 D-----------RQRKSSSMRWMAPEAIEHQMFSSKSDVWSFGICLYEIFT--------- 1013 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 L G + + ++ G R +P+ CP +Y LM+ CW RP F Sbjct 1014 -----LGGTPYPTCVTENILKHIKNGSRNLQPEYCPSALYDLMQLCWRAPPQDRPKF 1065 Score = 61.2 bits (147), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 47/163 (29%), Positives = 72/163 (44%), Gaps = 22/163 (13%) Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 +A Q+A+ + +L N VHGN+C R +L+++ + I+++D GVG R+ + Sbjct 931 IAHQIANGMEWLGNVPCVHGNLCCRKVLISK-------TKTIRITDYGVG----DRQRKS 979 Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS-RSPSEKEHFYQRQHR 832 + W+APE + S+ D W FG L EI G P + + + +H Sbjct 980 SSMRWMAPEAIE--HQMFSSKSDVWSFGICLYEIFTLGGTPYPTCVTENILKHIKNGSRN 1037 Query 833 LPEPSCPQ-LATLTSQCLTYEPTQRPSFRTI-------LRDLT 867 L CP L L C P RP F L+DLT Sbjct 1038 LQPEYCPSALYDLMQLCWRAPPQDRPKFSLCSELIEKQLKDLT 1080 >sp|Q9LDZ5|PBL21_ARATH Probable serine/threonine-protein kinase PBL21 OS=Arabidopsis thaliana OX=3702 GN=PBL21 PE=1 SV=1 Length=381 Score = 97.1 bits (240), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 91/313 (29%), Positives = 143/313 (46%), Gaps = 43/313 (14%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R +++ LGEG FG+V Y D +G++VA+K L D G Q + E+ +L L Sbjct 76 RNFREVNLLGEGGFGRV----YKGRLD-SGQVVAIKQLNPD-GLQGNREFIVEVLMLSLL 129 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICE 1009 +H +++ G C G++ L LV EY+P+GSL D+L + + + A Sbjct 130 HHPNLVTLIGYCT-SGDQRL-LVYEYMPMGSLEDHLFDLESNQEPLSWNTRMKIAVGAAR 187 Query 1010 GMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G+ YLH I+RDL + N+LLD + K+ DFGLAK P G + V Sbjct 188 GIEYLHCTANPPVIYRDLKSANILLDKEFSPKLSDFGLAKLGPVGDRTH-VSTRVMGTYG 246 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL---- 1122 + APE K SD++ FGV L EL+T K ++L G QG+ ++ Sbjct 247 YCAPEYAMSGKLTVKSDIYCFGVVLLELITG--------RKAIDL-GQKQGEQNLVTWSR 297 Query 1123 -------RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV--- 1172 + L++ R P +C ++ C EA +RP +++ L+ + Sbjct 298 PYLKDQKKFGHLVDPSLRGKYPRRCLNYAIAIIAMCLNEEAHYRPFIGDIVVALEYLAAQ 357 Query 1173 ---HEKYQGQAPS 1182 HE +PS Sbjct 358 SRSHEARNVSSPS 370 Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 71/267 (27%), Positives = 112/267 (42%), Gaps = 51/267 (19%) Query 557 ETSNLIIMRGARASP------RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRV 610 E+ + I++ G SP R+ +L+ + +E+ + LG+G VY+GRL Sbjct 43 ESISGILVNGKVNSPIPGGGARSFTFKELAAATRNFREV---NLLGEGGFGRVYKGRL-- 97 Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670 D GQ V +K L+P F ++S + H +L Sbjct 98 ---------------------DSGQV--VAIKQLNPDGLQGNREFIVEVLMLSLLHHPNL 134 Query 671 AFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAW--KMVVAQQLASALSYLE- 726 + G C G + ++V EY+ G L D E P++W +M +A A + YL Sbjct 135 VTLIGYCTSGDQRLLVYEYMPMGSLEDHLFDLESNQEPLSWNTRMKIAVGAARGIEYLHC 194 Query 727 --NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERVE-RIPWLAPE 782 N +++ ++ NILL + SP KLSD G+ LG + V R+ Sbjct 195 TANPPVIYRDLKSANILLDK-----EFSP--KLSDFGLAKLGPVGDRTHVSTRVMGTYGY 247 Query 783 CLPGGANS--LSTAMDKWGFGATLLEI 807 C P A S L+ D + FG LLE+ Sbjct 248 CAPEYAMSGKLTVKSDIYCFGVVLLEL 274 >sp|Q9SF86|PCRK1_ARATH Serine/threonine-protein kinase PCRK1 OS=Arabidopsis thaliana OX=3702 GN=PCRK1 PE=1 SV=1 Length=418 Score = 97.4 bits (241), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 71/204 (35%), Positives = 103/204 (50%), Gaps = 13/204 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG FG V D + ++ VAVK L G Q W E++ L + H +++K Sbjct 90 IGEGGFGCVFRGTVRNLEDSSVKIEVAVKQL-GKRGLQGHKEWVTEVNFLGIVEHTNLVK 148 Query 962 YKGCCEDQGEKSLQ--LVMEYVPLGSLRDYLPRHSIGLAQL---LLFAQQICEGMAYLHA 1016 G C + E+ +Q LV EY+P S+ +L S+ + L AQ G+ YLH Sbjct 149 LLGYCAEDDERGIQRLLVYEYMPNRSVEFHLSPRSLTVLTWDLRLRIAQDAARGLTYLHE 208 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPEC 1072 + I RD + N+LLD D K+ DFGLA+ P EG + V D + + APE Sbjct 209 EMEFQIIFRDFKSSNILLDEDWKAKLSDFGLARLGPSEGLTH--VSTDVVGTMGYAAPEY 266 Query 1073 LKEYKFYYASDVWSFGVTLYELLT 1096 ++ + SDVW +GV LYEL+T Sbjct 267 IQTGRLTSKSDVWGYGVFLYELIT 290 Score = 51.2 bits (121), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 55/239 (23%), Positives = 101/239 (42%), Gaps = 33/239 (14%) Query 659 ASLMSQVSHTHLAFVHGVCV----RGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 + + V HT+L + G C RG + ++V EY+ + ++ L R + W ++ Sbjct 135 VNFLGIVEHTNLVKLLGYCAEDDERGIQRLLVYEYMPNRSVEFHLS-PRSLTVLTWDLRL 193 Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 +AQ A L+YL + ++ + NILL A+ + + P GL +S Sbjct 194 RIAQDAARGLTYLHEEMEFQIIFRDFKSSNILLDEDWKAKLSDFGLARLGPSEGLTHVS- 252 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ- 828 + V + + APE + G L++ D WG+G L E+ G P+ P ++ + Sbjct 253 TDVVGTMGYAAPEYIQTG--RLTSKSDVWGYGVFLYEL-ITGRRPVDRNRPKGEQKLLEW 309 Query 829 --------RQHRL----------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 R+ +L P S +LA + ++CL RP +L + ++ Sbjct 310 VRPYLSDTRKFKLILDPRLEGKYPIKSVQKLAVVANRCLVRNSKARPKMSEVLEMVNKI 368 >sp|P09619|PGFRB_HUMAN Platelet-derived growth factor receptor beta OS=Homo sapiens OX=9606 GN=PDGFRB PE=1 SV=1 Length=1106 Score = 100 bits (248), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 58/168 (35%), Positives = 87/168 (52%), Gaps = 14/168 (8%) Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + L+ F+ Q+ GM +L +++ +HRDLAARNVL+ +LVKI DFGLA+ + Y Sbjct 798 LSYMDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNY 857 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + P+ W APE + + SDVWSFG+ L+E+ T T + EL Sbjct 858 IS-KGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGG------TPYPELPMN 910 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 Q ++RG R+ +P E+Y +M+ CWE + RP F Sbjct 911 EQ-------FYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPF 951 Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 42/155 (27%), Positives = 73/155 (47%), Gaps = 24/155 (15%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A+ + +L +KN VH ++ RN+L + EG +K+ D G+ + + + Sbjct 809 QVANGMEFLASKNCVHRDLAARNVL-----ICEGK--LVKICDFGLARDIMRDSNYISKG 861 Query 776 -----IPWLAPECLPGGANSLSTAM-DKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-- 827 + W+APE + NSL T + D W FG L EI G P +E+ FY Sbjct 862 STFLPLKWMAPESI---FNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQ--FYNA 916 Query 828 -QRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSF 859 +R +R+ +P + ++ + +C + RP F Sbjct 917 IKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPF 951 Score = 38.5 bits (88), Expect = 0.55, Method: Compositional matrix adjust. Identities = 29/95 (31%), Positives = 42/95 (44%), Gaps = 4/95 (4%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLY-HEH 958 R LG G FG+V + M VAVK LK+ + E+ I+ L H + Sbjct 604 RTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLN 663 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993 ++ G C G + ++ EY G L DYL R+ Sbjct 664 VVNLLGACTKGG--PIYIITEYCRYGDLVDYLHRN 696 >sp|Q55CA6|Y0146_DICDI Probable serine/threonine-protein kinase DDB_G0270146 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0270146 PE=3 SV=1 Length=635 Score = 99.4 bits (246), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 75/267 (28%), Positives = 126/267 (47%), Gaps = 28/267 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G F V + N +G+ VA+K K+ + S E DIL+ L HE+I++ Sbjct 83 IGKGAFATV----FKGLNTLSGDFVAIKRFEKSKISNEQHSSVSTEFDILQRLNHENIVR 138 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLHAQHYI 1020 G ++ E + + +EY+ GSL L L+ + + + +G+ YLH + I Sbjct 139 ILG--REENENYIYIFLEYMENGSLSTILNNFGTFPESLICNYVENVLKGLVYLHQEGVI 196 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLA-KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 HRD+ A N+L++ K+ DFG A + + E + Y V +P +W APE ++ Sbjct 197 HRDIKAANILINKAGEAKLSDFGTAGEIIKESDKRYSVV---GTP-YWMAPEVIEISGHC 252 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SD+WS G T+ EL T PP L +G + R+ + +R P PD Sbjct 253 QVSDIWSLGCTIIELFTSY-----PPYFDLNPLG------AMYRICQ----DDRPPLPDD 297 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLI 1166 E+ + ++ C+ R T + L+ Sbjct 298 ISSELANFLERCFCKSTEERATAKELL 324 Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 47/228 (21%), Positives = 92/228 (40%), Gaps = 21/228 (9%) Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 K+ + H ++ F ++ +++H ++ + G + EY+E+G L L Sbjct 112 KISNEQHSSVSTEF----DILQRLNHENIVRILGREENENYIYIFLEYMENGSLSTILNN 167 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 G P + + + L YL + ++H ++ NIL+ + G A KLSD G Sbjct 168 -FGTFPESLICNYVENVLKGLVYLHQEGVIHRDIKAANILINKAGEA-------KLSDFG 219 Query 762 VGLGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + ++ + W+APE + + D W G T++E+ F P Sbjct 220 TAGEIIKESDKRYSVVGTPYWMAPEVIEISGH--CQVSDIWSLGCTIIEL-FTSYPPYFD 276 Query 818 RSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 +P + + R LP+ +LA +C +R + + +L Sbjct 277 LNPLGAMYRICQDDRPPLPDDISSELANFLERCFCKSTEERATAKELL 324 >sp|Q7ZYJ0|TAO1B_XENLA Serine/threonine-protein kinase TAO1-B OS=Xenopus laevis OX=8355 GN=taok1-b PE=2 SV=1 Length=1001 Score = 100 bits (248), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 80/239 (33%), Positives = 119/239 (50%), Gaps = 32/239 (13%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956 +R++G G FG V + +D T E+VA+K + + G Q W+ +E+ L+ + H Sbjct 31 LREIGHGSFGAV-YFAHDAR---TSEVVAIKKM-SYSGKQSNEKWQDIIKEVKFLQRIQH 85 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014 + I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL Sbjct 86 PNSIEYKGCY--LREHTAWLVMEYC-LGSASDLLEVHKKPLQEIEIAAITHGALQGLAYL 142 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071 H+ + IHRD+ A N+LL VK+ DFG A V + + +P +W APE Sbjct 143 HSHNLIHRDIKAGNILLTEPGQVKLADFGSASIVSPANSFV------GTP-YWMAPEVIL 195 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP----TKFLELIGIAQGQMTVLRLTE 1126 + E ++ DVWS G+T EL + + PP L IAQ + L+ TE Sbjct 196 AMDEGQYDGKVDVWSLGITCVEL-----AERKPPLFNMNAMSALYHIAQNESPTLQSTE 249 Score = 35.4 bits (80), Expect = 4.1, Method: Compositional matrix adjust. Identities = 26/88 (30%), Positives = 37/88 (42%), Gaps = 8/88 (9%) Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781 L+YL + NL+H ++ NILL G +KL+D G V W+AP Sbjct 139 LAYLHSHNLIHRDIKAGNILLTEPGQ-------VKLADFGSASIVSPANSFVGTPYWMAP 191 Query 782 EC-LPGGANSLSTAMDKWGFGATLLEIC 808 E L +D W G T +E+ Sbjct 192 EVILAMDEGQYDGKVDVWSLGITCVELA 219 >sp|Q55EC7|GEFX_DICDI RasGEF domain-containing serine/threonine-protein kinase X OS=Dictyostelium discoideum OX=44689 GN=gefX PE=2 SV=1 Length=960 Score = 99.8 bits (247), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 61/195 (31%), Positives = 101/195 (52%), Gaps = 11/195 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FG V CY G VA+K ++ P++ +E+ +L++L H I+ + Sbjct 27 IGKGSFGSVFRGCY------LGLDVAIKKIEKADDPEYLKYIDREVSMLQSLRHPFIVNF 80 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G C L +V E+V G +R L + IG + + A + + M +LHA+ IH Sbjct 81 SGICVHSS--GLYIVTEFVSGGDVRQLLKKTPPIGWDKRVSIAVDLAKAMVFLHAKKIIH 138 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RDL ++N+LLD + +++ DFG A+ + + + G W APE L + + Sbjct 139 RDLKSKNILLDEFQRIRLCDFGFARMSEQTKKSRHMTMCGTEG--WVAPEILLGMSYDTS 196 Query 1082 SDVWSFGVTLYELLT 1096 DV+S+GV L EL+T Sbjct 197 CDVFSYGVVLAELIT 211 Score = 71.2 bits (173), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 69/253 (27%), Positives = 110/253 (43%), Gaps = 38/253 (15%) Query 637 LRVVLKVLDPSHHDIALAFYE-TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 L V +K ++ + L + + S++ + H + G+CV +VTE+V G + Sbjct 43 LDVAIKKIEKADDPEYLKYIDREVSMLQSLRHPFIVNFSGICVHSSGLYIVTEFVSGGDV 102 Query 696 DVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L++ P+ W ++ +A LA A+ +L K ++H ++ +NILL Sbjct 103 RQLLKKTP---PIGWDKRVSIAVDLAKAMVFLHAKKIIHRDLKSKNILLDEFQR------ 153 Query 754 FIKLSDPGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 I+L D G +S + + R W+APE L G S T+ D + +G L E Sbjct 154 -IRLCD--FGFARMSEQTKKSRHMTMCGTEGWVAPEILLGM--SYDTSCDVFSYGVVLAE 208 Query 807 ICFDGEAP---LQSRSPS-----EKEHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQRP 857 + G P L RSP E Q+ P CP +L ++ +C YEP RP Sbjct 209 L-ITGRKPGVDLWVRSPETCFDINPEELKQKSI----PGCPSELISVCVECCLYEPLTRP 263 Query 858 SFRTILRDLTRLQ 870 F IL L Q Sbjct 264 KFDEILSQLKVCQ 276 >sp|Q05030|PGFRB_RAT Platelet-derived growth factor receptor beta OS=Rattus norvegicus OX=10116 GN=Pdgfrb PE=2 SV=2 Length=1097 Score = 99.8 bits (247), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 65/188 (35%), Positives = 94/188 (50%), Gaps = 19/188 (10%) Query 980 YVPLGSLRDY---LPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034 YVP R Y L S + L+ F+ Q+ GM +L +++ +HRDLAARNVL+ Sbjct 777 YVPSAPERTYRATLINDSPVLSYTDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEG 836 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 +LVKI DFGLA+ + Y + P+ W APE + + SDVWSFG+ L+E+ Sbjct 837 KLVKICDFGLARDIMRDSNYIS-KGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEI 895 Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154 T T + EL Q ++RG R+ +P E+Y +M+ CWE Sbjct 896 FTLGG------TPYPELPMNDQ-------FYNAIKRGYRMAQPAHASDEIYEIMQKCWEE 942 Query 1155 EASFRPTF 1162 + RP F Sbjct 943 KFETRPPF 950 Score = 49.3 bits (116), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 41/155 (26%), Positives = 73/155 (47%), Gaps = 24/155 (15%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A+ + +L +KN VH ++ RN+L + EG +K+ D G+ + + + Sbjct 808 QVANGMEFLASKNCVHRDLAARNVL-----ICEGK--LVKICDFGLARDIMRDSNYISKG 860 Query 776 -----IPWLAPECLPGGANSLSTAM-DKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-- 827 + W+APE + NSL T + D W FG L EI G P +++ FY Sbjct 861 STFLPLKWMAPESI---FNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQ--FYNA 915 Query 828 -QRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSF 859 +R +R+ +P + ++ + +C + RP F Sbjct 916 IKRGYRMAQPAHASDEIYEIMQKCWEEKFETRPPF 950 Score = 38.5 bits (88), Expect = 0.52, Method: Compositional matrix adjust. Identities = 29/95 (31%), Positives = 42/95 (44%), Gaps = 4/95 (4%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLY-HEH 958 R LG G FG+V + M VAVK LK+ + E+ I+ L H + Sbjct 603 RTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLN 662 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993 ++ G C G + ++ EY G L DYL R+ Sbjct 663 VVNLLGACTKGG--PIYIITEYCRYGDLVDYLHRN 695 >sp|Q91821|MELK_XENLA Maternal embryonic leucine zipper kinase OS=Xenopus laevis OX=8355 GN=melk PE=1 SV=2 Length=651 Score = 99.0 bits (245), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 70/204 (34%), Positives = 108/204 (53%), Gaps = 12/204 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 +Y + +G G F KV L ++ TGE VA+K + + K EID ++ L Sbjct 11 KYYELHETVGTGGFAKVKL----ASHLITGEKVAIKIMDKESLGDDLPRVKTEIDAMKNL 66 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAY 1013 H+H+ + E K + +V+EY P G L DY+ + + + +F +QI +AY Sbjct 67 SHQHVCRLYHVIE--TPKKIFMVLEYCPGGELFDYIIAKDRLTEEEARVFFRQIVSAVAY 124 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +H+Q Y HRDL N+L+D D+ +K+ DFGL A P+G Y + SP + APE + Sbjct 125 IHSQGYAHRDLKPENLLIDEDQNLKLIDFGLC-AKPKGGLDYHLMTCCGSPAY-AAPELI 182 Query 1074 KEYKFYYAS--DVWSFGVTLYELL 1095 + K Y S D+WS GV +Y L+ Sbjct 183 QG-KAYIGSEADIWSMGVLMYALM 205 >sp|Q28GW8|MELK_XENTR Maternal embryonic leucine zipper kinase OS=Xenopus tropicalis OX=8364 GN=melk PE=2 SV=1 Length=652 Score = 99.0 bits (245), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 70/204 (34%), Positives = 108/204 (53%), Gaps = 12/204 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 +Y + +G G F KV L ++ TGE VA+K + + K EID ++ L Sbjct 11 KYYELHETIGTGGFAKVKL----ASHLTTGEKVAIKIMDKESLGDDLPRVKTEIDAMKNL 66 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAY 1013 H+H+ + E + + +V+EY P G L DY+ + + + +F +QI +AY Sbjct 67 SHQHVCRLYHVIETPNK--IFMVLEYCPGGELFDYIIAKDRLTEDEARVFFRQIVSAVAY 124 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +H+Q Y HRDL N+L+D D+ +K+ DFGL A P+G Y + SP + APE L Sbjct 125 IHSQGYAHRDLKPENLLIDEDQNLKLIDFGLC-AKPKGGLDYHLMTCCGSPAY-AAPE-L 181 Query 1074 KEYKFYYAS--DVWSFGVTLYELL 1095 + K Y S D+WS GV +Y L+ Sbjct 182 IQGKAYIGSEADIWSMGVLMYALM 205 Score = 35.0 bits (79), Expect = 5.1, Method: Compositional matrix adjust. Identities = 54/234 (23%), Positives = 96/234 (41%), Gaps = 19/234 (8%) Query 638 RVVLKVLDPSHHDIALAFYETA-SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL- 695 +V +K++D L +T M +SH H+ ++ V + MV EY G L Sbjct 38 KVAIKIMDKESLGDDLPRVKTEIDAMKNLSHQHVCRLYHVIETPNKIFMVLEYCPGGELF 97 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 D + ++R A V +Q+ SA++Y+ ++ H ++ N+L+ + Sbjct 98 DYIIAKDRLTEDEA--RVFFRQIVSAVAYIHSQGYAHRDLKPENLLIDE-------DQNL 148 Query 756 KLSDPGVGL---GALSREERV--ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 KL D G+ G L + APE + G A + + D W G L+ Sbjct 149 KLIDFGLCAKPKGGLDYHLMTCCGSPAYAAPELIQGKA-YIGSEADIWSMGV-LMYALMC 206 Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 G P + + + ++ +P+ P L SQ L +P +R S + +L Sbjct 207 GYLPFDDDNVMVLYKKIMRGKYEIPKWLSPGSVLLLSQMLQVDPKKRISVKHLL 260 >sp|P05622|PGFRB_MOUSE Platelet-derived growth factor receptor beta OS=Mus musculus OX=10090 GN=Pdgfrb PE=1 SV=2 Length=1098 Score = 99.8 bits (247), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 65/188 (35%), Positives = 94/188 (50%), Gaps = 19/188 (10%) Query 980 YVPLGSLRDY---LPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034 YVP R Y L S + L+ F+ Q+ GM +L +++ +HRDLAARNVL+ Sbjct 777 YVPSAPERTYRATLINDSPVLSYTDLVGFSYQVANGMDFLASKNCVHRDLAARNVLICEG 836 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 +LVKI DFGLA+ + Y + P+ W APE + + SDVWSFG+ L+E+ Sbjct 837 KLVKICDFGLARDIMRDSNYIS-KGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEI 895 Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154 T T + EL Q ++RG R+ +P E+Y +M+ CWE Sbjct 896 FTLGG------TPYPELPMNDQ-------FYNAIKRGYRMAQPAHASDEIYEIMQKCWEE 942 Query 1155 EASFRPTF 1162 + RP F Sbjct 943 KFETRPPF 950 Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 41/155 (26%), Positives = 73/155 (47%), Gaps = 24/155 (15%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER- 775 Q+A+ + +L +KN VH ++ RN+L + EG +K+ D G+ + + + Sbjct 808 QVANGMDFLASKNCVHRDLAARNVL-----ICEGK--LVKICDFGLARDIMRDSNYISKG 860 Query 776 -----IPWLAPECLPGGANSLSTAM-DKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-- 827 + W+APE + NSL T + D W FG L EI G P +++ FY Sbjct 861 STFLPLKWMAPESI---FNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNDQ--FYNA 915 Query 828 -QRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSF 859 +R +R+ +P + ++ + +C + RP F Sbjct 916 IKRGYRMAQPAHASDEIYEIMQKCWEEKFETRPPF 950 Score = 38.1 bits (87), Expect = 0.58, Method: Compositional matrix adjust. Identities = 29/95 (31%), Positives = 42/95 (44%), Gaps = 4/95 (4%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLY-HEH 958 R LG G FG+V + M VAVK LK+ + E+ I+ L H + Sbjct 603 RTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLN 662 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993 ++ G C G + ++ EY G L DYL R+ Sbjct 663 VVNLLGACTKGG--PIYIITEYCRYGDLVDYLHRN 695 >sp|Q9SFT7|PBL26_ARATH Probable serine/threonine-protein kinase PBL26 OS=Arabidopsis thaliana OX=3702 GN=PBL26 PE=2 SV=1 Length=414 Score = 97.1 bits (240), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 89/279 (32%), Positives = 134/279 (48%), Gaps = 22/279 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG+V Y + TG +VAVK L + G Q + E+ +L L+H+H++ Sbjct 85 IGEGGFGRV----YKGKLEKTGMIVAVKQLDRN-GLQGNKEFIVEVLMLSLLHHKHLVNL 139 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 G C D G++ L LV EY+ GSL D+L + + + A G+ YLH + Sbjct 140 IGYCAD-GDQRL-LVYEYMSRGSLEDHLLDLTPDQIPLDWDTRIRIALGAAMGLEYLHDK 197 Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 I+RDL A N+LLD + K+ DFGLAK P G + + V + APE + Sbjct 198 ANPPVIYRDLKAANILLDGEFNAKLSDFGLAKLGPVGDKQH-VSSRVMGTYGYCAPEYQR 256 Query 1075 EYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTV-LRLTELLER 1130 + SDV+SFGV L EL+T D+++ P L+ AQ R EL + Sbjct 257 TGQLTTKSDVYSFGVVLLELITGRRVIDTTR--PKDEQNLVTWAQPVFKEPSRFPELADP 314 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P+K + + C + EA+ RP +++ L Sbjct 315 SLEGVFPEKALNQAVAVAAMCLQEEATVRPLMSDVVTAL 353 Score = 57.8 bits (138), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 75/311 (24%), Positives = 122/311 (39%), Gaps = 65/311 (21%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 K Q +G+G VY+G+L G + V +K LD Sbjct 77 KNFRQECLIGEGGFGRVYKGKLEKTG------------------------MIVAVKQLDR 112 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGH 705 + F ++S + H HL + G C G + ++V EY+ G L D L Sbjct 113 NGLQGNKEFIVEVLMLSLLHHKHLVNLIGYCADGDQRLLVYEYMSRGSLEDHLLDLTPDQ 172 Query 706 VPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 +P+ W ++ +A A L YL +K +++ ++ NILL A KLSD Sbjct 173 IPLDWDTRIRIALGAAMGLEYLHDKANPPVIYRDLKAANILLDGEFNA-------KLSDF 225 Query 761 GVG-LGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ LG + ++ V + APE G L+T D + FG LLE+ G Sbjct 226 GLAKLGPVGDKQHVSSRVMGTYGYCAPEYQRTG--QLTTKSDVYSFGVVLLEL-ITGRRV 282 Query 815 LQSRSPSEKEHF-------YQRQHRLPEPSCP------------QLATLTSQCLTYEPTQ 855 + + P ++++ ++ R PE + P Q + + CL E T Sbjct 283 IDTTRPKDEQNLVTWAQPVFKEPSRFPELADPSLEGVFPEKALNQAVAVAAMCLQEEATV 342 Query 856 RPSFRTILRDL 866 RP ++ L Sbjct 343 RPLMSDVVTAL 353 >sp|O61122|SVKA_DICDI Serine/threonine-protein kinase svkA OS=Dictyostelium discoideum OX=44689 GN=svkA PE=1 SV=1 Length=478 Score = 97.8 bits (242), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 62/211 (29%), Positives = 103/211 (49%), Gaps = 13/211 (6%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 S DP + R K +G+G FG+V + N T E +A+K + + Sbjct 3 SKKGDPEELYVRQEK----IGKGSFGEV----FKGINKKTNETIAIKTIDLEDAEDEIED 54 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLF 1003 +QEI++L + KY G +G K L ++MEY+ GS+ D + + + Sbjct 55 IQQEINVLSQCESPFVTKYFGSFL-KGSK-LWIIMEYLAGGSVLDLMKPGPFDEGYIAII 112 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 +++ +G+ YLH++ IHRD+ A NVLL VK+ DFG++ + + R Sbjct 113 LRELLKGLEYLHSEGKIHRDIKAANVLLSASGDVKLADFGVSGQL---TDQMTKRNTFVG 169 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 FW APE +K+ + +D+WS G+T E+ Sbjct 170 TPFWMAPEVIKQTGYDSKADIWSMGITALEM 200 Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 63/273 (23%), Positives = 111/273 (41%), Gaps = 42/273 (15%) Query 614 GDPEEGKMDDED-------PLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQV 665 GDPEE + E + G ++ + +K +D D + +++SQ Sbjct 6 GDPEELYVRQEKIGKGSFGEVFKGINKKTNETIAIKTIDLEDAEDEIEDIQQEINVLSQC 65 Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWLRRERGHVPMAWKMVVAQQLASALSY 724 + G ++G + ++ EY+ G LD+ + G + ++ ++L L Y Sbjct 66 ESPFVTKYFGSFLKGSKLWIIMEYLAGGSVLDLM---KPGPFDEGYIAIILRELLKGLEY 122 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS-----REERVERIPWL 779 L ++ +H ++ N+LL+ G +KL+D GV G L+ R V W+ Sbjct 123 LHSEGKIHRDIKAANVLLSASG-------DVKLADFGVS-GQLTDQMTKRNTFVGTPFWM 174 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP 839 APE + + D W G T LE+ GE P P + +P+ P Sbjct 175 APEVI--KQTGYDSKADIWSMGITALEMA-KGEPPRADLHP------MRALFLIPKDPPP 225 Query 840 QLATLTSQ--------CLTYEPTQRPSFRTILR 864 L S+ CL +P QRP+ + +L+ Sbjct 226 TLEGNFSKGFKEFCALCLNKDPNQRPTAKDLLK 258 >sp|F4HQ17|LRL14_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 1.4 OS=Arabidopsis thaliana OX=3702 GN=LRK10L-1.4 PE=2 SV=2 Length=663 Score = 99.0 bits (245), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 79/283 (28%), Positives = 135/283 (48%), Gaps = 18/283 (6%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R+LG+G FG V Y DG VAVK L + + +K EI+IL++L H +++ Sbjct 338 RELGDGGFGTVY---YGVLKDGRA--VAVKRL-YERSLKRVEQFKNEIEILKSLKHPNLV 391 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLH 1015 GC + + L LV EY+ G+L ++L + + L A + +++LH Sbjct 392 ILYGCTS-RHSRELLLVYEYISNGTLAEHLHGNRAEARPLCWSTRLNIAIETASALSFLH 450 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + IHRD+ N+LLD++ VK+ DFGL++ P + G + PE + Sbjct 451 IKGIIHRDIKTTNILLDDNYQVKVADFGLSRLFPMDQTHISTAPQGTPG--YVDPEYYQC 508 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF-LELIGIAQGQMTVLRLTELLERG--- 1131 Y+ SDV+SFGV L EL++ ++ + + L +A ++ L EL++ Sbjct 509 YQLNEKSDVYSFGVVLTELISSKEAVDITRHRHDINLANMAVSKIQNNALHELVDSSLGY 568 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + P + V L C + E RP + ++ IL+ + + Sbjct 569 DNDPEVRRKMMAVAELAFRCLQQERDVRPAMDEIVEILRGIKD 611 Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 46/171 (27%), Positives = 78/171 (46%), Gaps = 24/171 (14%) Query 655 FYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDVWLRRERGHV-PMAW-- 710 F ++ + H +L ++G R E ++V EY+ +G L L R P+ W Sbjct 375 FKNEIEILKSLKHPNLVILYGCTSRHSRELLLVYEYISNGTLAEHLHGNRAEARPLCWST 434 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 ++ +A + ASALS+L K ++H ++ NILL + +K++D G LSR Sbjct 435 RLNIAIETASALSFLHIKGIIHRDIKTTNILL-------DDNYQVKVADFG-----LSRL 482 Query 771 ERVERIPW-LAPECLPGGAN-------SLSTAMDKWGFGATLLEICFDGEA 813 +++ AP+ PG + L+ D + FG L E+ EA Sbjct 483 FPMDQTHISTAPQGTPGYVDPEYYQCYQLNEKSDVYSFGVVLTELISSKEA 533 >sp|Q9P289|STK26_HUMAN Serine/threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 Length=416 Score = 97.1 bits (240), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 73/268 (27%), Positives = 121/268 (45%), Gaps = 24/268 (9%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 K+ +G+G FG+V + ++ T ++VA+K + + +QEI +L + Sbjct 26 KLERIGKGSFGEV----FKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSY 81 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 + KY G +G K L ++MEY+ GS D L Q+ ++I +G+ YLH++ Sbjct 82 VTKYYGSYL-KGSK-LWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEK 139 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ A NVLL VK+ DFG+A + + R FW APE +++ + Sbjct 140 KIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIK---RNTFVGTPFWMAPEVIQQSAY 196 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 +D+WS G+T EL + PP M +R+ L+ + Sbjct 197 DSKADIWSLGITAIEL-----AKGEPPN----------SDMHPMRVLFLIPKNNPPTLVG 241 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLI 1166 + C + SFRPT + L+ Sbjct 242 DFTKSFKEFIDACLNKDPSFRPTAKELL 269 Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 65/310 (21%), Positives = 129/310 (42%), Gaps = 58/310 (19%) Query 570 SPRTLNLSQLSFHRVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 SP + + + + D +E+ T+L +G+G+ V++G +D+ Sbjct 4 SPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKG--------------IDN----- 44 Query 629 PGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 R Q++ V +K++D D + +++SQ +++ +G ++G + ++ Sbjct 45 ----RTQQV-VAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIM 99 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 EY+ G LR G + +++ L YL ++ +H ++ N+LL+ G Sbjct 100 EYLGGGSALDLLRA--GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQG- 156 Query 748 AEGTSPFIKLSDPGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 +KL+D GV G L+ R V W+APE + A + D W G Sbjct 157 ------DVKLADFGVA-GQLTDTQIKRNTFVGTPFWMAPEVIQQSA--YDSKADIWSLGI 207 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLA--------TLTSQCLTYEPT 854 T +E+ + P+ H + +P+ + P L CL +P+ Sbjct 208 TAIELA-------KGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPS 260 Query 855 QRPSFRTILR 864 RP+ + +L+ Sbjct 261 FRPTAKELLK 270 >sp|Q9FPR3|EDR1_ARATH Serine/threonine-protein kinase EDR1 OS=Arabidopsis thaliana OX=3702 GN=EDR1 PE=1 SV=1 Length=933 Score = 99.4 bits (246), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 81/275 (29%), Positives = 125/275 (45%), Gaps = 28/275 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G +G+V Y GT E+ K L D + ++ E+ I+R L H +++ + Sbjct 675 IGLGSYGEV----YHADWHGT-EVAVKKFLDQDFSGAALAEFRSEVRIMRRLRHPNVVFF 729 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH-- 1018 G +L +V E++P GSL L P+ I + + A + GM LH Sbjct 730 LGAV--TRPPNLSIVTEFLPRGSLYRILHRPKSHIDERRRIKMALDVAMGMNCLHTSTPT 787 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRDL N+L+DN+ VK+GDFGL++ H + + W APE L+ Sbjct 788 IVHRDLKTPNLLVDNNWNVKVGDFGLSRL---KHNTFLSSKSTAGTPEWMAPEVLRNEPS 844 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 DV+SFGV L+EL T L L M V+ R RL P Sbjct 845 NEKCDVYSFGVILWELAT------------LRLPWRGMNPMQVVGAVGFQNR--RLEIPK 890 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + V ++ CW+T+ + RP+F L +LK ++ Sbjct 891 ELDPVVGRIILECWQTDPNLRPSFAQLTEVLKPLN 925 Score = 55.5 bits (132), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 61/246 (25%), Positives = 103/246 (42%), Gaps = 27/246 (11%) Query 639 VVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V K LD ALA F +M ++ H ++ F G R P +VTE++ G L Sbjct 694 AVKKFLDQDFSGAALAEFRSEVRIMRRLRHPNVVFFLGAVTRPPNLSIVTEFLPRGSLYR 753 Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENK--NLVHGNVCGRNILLARLGLAEGTSPFI 755 L R + H+ ++ +A +A ++ L +VH ++ N+L+ + + Sbjct 754 ILHRPKSHIDERRRIKMALDVAMGMNCLHTSTPTIVHRDLKTPNLLV-------DNNWNV 806 Query 756 KLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--- 808 K+ D G+ LS + W+APE L + + D + FG L E+ Sbjct 807 KVGDFGLSRLKHNTFLSSKSTAGTPEWMAPEVLRNEPS--NEKCDVYSFGVILWELATLR 864 Query 809 --FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF---RTIL 863 + G P+Q F R+ +P+ P + + +C +P RPSF +L Sbjct 865 LPWRGMNPMQVVGAV---GFQNRRLEIPKELDPVVGRIILECWQTDPNLRPSFAQLTEVL 921 Query 864 RDLTRL 869 + L RL Sbjct 922 KPLNRL 927 >sp|Q924U5|TESK2_RAT Dual specificity testis-specific protein kinase 2 OS=Rattus norvegicus OX=10116 GN=Tesk2 PE=2 SV=1 Length=570 Score = 98.2 bits (243), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 74/281 (26%), Positives = 125/281 (44%), Gaps = 33/281 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G F +V + + +G+ V ALK + +R+ +E+ ++ L H +I+++ Sbjct 64 IGSGFFSEV----FKVRHRASGQ---VMALKMNTLSSNRANLLKEMQLMNRLSHPNILRF 116 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G C QG+ L + EY+ G+L L + + + A I G++YLH + H Sbjct 117 MGVCVHQGQ--LHALTEYINSGNLEQLLDSNLYLPWTVRVKLAYDIAVGLSYLHFKGIFH 174 Query 1022 RDLAARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 RDL ++N L+ D + DFGLA+ +P+ SP FW APE L++ + Sbjct 175 RDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGSEKLAVVGSP-FWMAPEVLRDEPY 233 Query 1079 YYASDVWSFGVTLYELLT--HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 +DV+S+G+ L E++ D P T+ L A M Sbjct 234 NEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMV---------------- 277 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 CP + L NC + RP+FE + L+ + + Q Sbjct 278 -GDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLEEIMSRLQ 317 Score = 62.4 bits (150), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 68/262 (26%), Positives = 111/262 (42%), Gaps = 36/262 (14%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 R GQ + + + L + ++ + LM+++SH ++ GVCV + +TEY+ Sbjct 78 RASGQVMALKMNTLSSNRANL----LKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYI 133 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR------ 744 G L+ L ++P ++ +A +A LSYL K + H ++ +N L+ R Sbjct 134 NSGNLEQLLDSNL-YLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYS 192 Query 745 -----LGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 GLAE K+ D +G L+ V W+APE L + D + Sbjct 193 AVVADFGLAE------KIPDASIGSEKLA---VVGSPFWMAPEVL--RDEPYNEKADVFS 241 Query 800 FGATLLEIC--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQR 856 +G L EI + R+ + + QH + + CP LT C +P R Sbjct 242 YGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGD--CPSDFLQLTFNCCNMDPKLR 299 Query 857 PSFRTILRDL----TRLQPHNL 874 PSF I + L +RLQ L Sbjct 300 PSFEEIGKTLEEIMSRLQEEEL 321 >sp|Q55E58|PATS1_DICDI Probable serine/threonine-protein kinase pats1 OS=Dictyostelium discoideum OX=44689 GN=pats1 PE=3 SV=1 Length=3184 Score = 100 bits (248), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 85/264 (32%), Positives = 131/264 (50%), Gaps = 46/264 (17%) Query 924 GEMVAVKALKA-----------DCG-PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 G+ VAVK LK D + + +++E ++ L H +I++ KG C D Sbjct 2268 GQTVAVKKLKTIENLDSPIEINDISLSKAFNEFRRECWVMSELEHPNIVQLKGLCLD--- 2324 Query 972 KSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQH--YIHRDLAAR 1027 L +V EY+P G+L +L + + + L L A I GMA+LH+ IHRDL + Sbjct 2325 -PLCIVTEYLPHGNLYSFLHKPEMEFSWLFRLKVALDISSGMAFLHSSTPPIIHRDLKSP 2383 Query 1028 NVLL-----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK-FYYA 1081 N+LL + + K+ DFGL+ G ++ ++P+ W APE L + K Sbjct 2384 NILLASINENAQTIAKVVDFGLS-----GLQHTITNRGVENPL-WLAPEILNKTKEASTQ 2437 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 +DV++FGV L+EL+T D F E+ G MT++ E + GER P+ CP Sbjct 2438 TDVYAFGVILWELVTRKD-------YFGEI-----GFMTLIE--EKVINGERPKIPEDCP 2483 Query 1142 CEVYHLMKNCWETEASFRPTFENL 1165 L+ CW+T+AS RP F + Sbjct 2484 EMYSKLIVECWQTDASQRPKFSEI 2507 Score = 69.7 bits (169), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 66/242 (27%), Positives = 114/242 (47%), Gaps = 21/242 (9%) Query 649 HDIALA-----FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 +DI+L+ F +MS++ H ++ + G+C+ P I VTEY+ HG L +L + Sbjct 2289 NDISLSKAFNEFRRECWVMSELEHPNIVQLKGLCL-DPLCI-VTEYLPHGNLYSFLHKPE 2346 Query 704 GHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 +++ VA ++S +++L + ++H ++ NILLA + E K+ D G Sbjct 2347 MEFSWLFRLKVALDISSGMAFLHSSTPPIIHRDLKSPNILLASIN--ENAQTIAKVVDFG 2404 Query 762 V-GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC----FDGEAPLQ 816 + GL VE WLAPE L ST D + FG L E+ + GE Sbjct 2405 LSGLQHTITNRGVENPLWLAPEIL-NKTKEASTQTDVYAFGVILWELVTRKDYFGEIGFM 2463 Query 817 SRSPSEKEHFYQRQHRLPEPSCPQL-ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + E++ + ++PE CP++ + L +C + +QRP F I L ++ Sbjct 2464 TL--IEEKVINGERPKIPE-DCPEMYSKLIVECWQTDASQRPKFSEIEDRLIKIAEAMFP 2520 Query 876 DV 877 D+ Sbjct 2521 DI 2522 >sp|Q99JT2|STK26_MOUSE Serine/threonine-protein kinase 26 OS=Mus musculus OX=10090 GN=Stk26 PE=1 SV=1 Length=416 Score = 96.7 bits (239), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 73/268 (27%), Positives = 121/268 (45%), Gaps = 24/268 (9%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 K+ +G+G FG+V + ++ T ++VA+K + + +QEI +L + Sbjct 26 KLERIGKGSFGEV----FKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSY 81 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 + KY G +G K L ++MEY+ GS D L Q+ ++I +G+ YLH++ Sbjct 82 VTKYYGSYL-KGSK-LWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEK 139 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ A NVLL VK+ DFG+A + + R FW APE +++ + Sbjct 140 KIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQ---IKRNTFVGTPFWMAPEVIQQSAY 196 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 +D+WS G+T EL + PP M +R+ L+ + Sbjct 197 DSKADIWSLGITAIEL-----AKGEPPN----------SDMHPMRVLFLIPKNNPPTLIG 241 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLI 1166 + C + SFRPT + L+ Sbjct 242 DFTKSFKEFIDACLNKDPSFRPTAKELL 269 Score = 49.3 bits (116), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 65/310 (21%), Positives = 129/310 (42%), Gaps = 58/310 (19%) Query 570 SPRTLNLSQLSFHRVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 SP + + + + D +E+ T+L +G+G+ V++G +D+ Sbjct 4 SPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKG--------------IDN----- 44 Query 629 PGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 R Q++ V +K++D D + +++SQ +++ +G ++G + ++ Sbjct 45 ----RTQQV-VAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIM 99 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 EY+ G LR G + +++ L YL ++ +H ++ N+LL+ G Sbjct 100 EYLGGGSALDLLRA--GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQG- 156 Query 748 AEGTSPFIKLSDPGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 +KL+D GV G L+ R V W+APE + A + D W G Sbjct 157 ------DVKLADFGVA-GQLTDTQIKRNTFVGTPFWMAPEVIQQSA--YDSKADIWSLGI 207 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--------ATLTSQCLTYEPT 854 T +E+ + P+ H + +P+ + P L CL +P+ Sbjct 208 TAIELA-------KGEPPNSDMHPMRVLFLIPKNNPPTLIGDFTKSFKEFIDACLNKDPS 260 Query 855 QRPSFRTILR 864 RP+ + +L+ Sbjct 261 FRPTAKELLK 270 >sp|Q7T6X2|YR826_MIMIV Putative serine/threonine-protein kinase/receptor R826 OS=Acanthamoeba polyphaga mimivirus OX=212035 GN=MIMI_R826 PE=3 SV=2 Length=1657 Score = 99.8 bits (247), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 75/248 (30%), Positives = 122/248 (49%), Gaps = 27/248 (11%) Query 927 VAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 VA+K +K H G ++EI L+ L+H +II G + ++ +V EY+ G+ Sbjct 1423 VAIKKFIKQKIDENHLLGIREEIAFLKKLHHPNIITMVGAS--LKKPNICIVTEYMAKGN 1480 Query 986 LRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGD 1041 LRD + + L Q + I +G++YLH+ IHRD+ N+L+D + VKI D Sbjct 1481 LRDAMRTCTPKLEWHQKIKILVNIAKGISYLHSFDPPIIHRDIKPSNILIDENWNVKIAD 1540 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FG A+ E R +P W APE ++ + DV+SFG+ ++E+LT Sbjct 1541 FGFARIKEENAIMTRC----GTPC-WTAPEIIRNDIYDEKVDVFSFGIVMWEVLT----C 1591 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + P IG +++T + R P CP E LM+ CW +++ RPT Sbjct 1592 KEP------FIG-----ANFMKITMDILEDVRPKIPQDCPEEFAKLMRKCWHAKSTKRPT 1640 Query 1162 FENLIPIL 1169 +++I +L Sbjct 1641 MDDVIIVL 1648 Score = 95.1 bits (235), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 89/295 (30%), Positives = 135/295 (46%), Gaps = 45/295 (15%) Query 891 VFHKRYLKKIRD--------------LGEGHFGKVSLYCYDPTNDGT--GEMVAVKALKA 934 +F R+ K I D LG G FG+V + GT G VAVK + Sbjct 766 IFSLRFRKGISDDWEIDFHELELGEQLGTGAFGEV--------HKGTWRGTEVAVKMISP 817 Query 935 D--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992 D +K E+ ++ TL H +++ + + + +VME++ LGSL D L Sbjct 818 DKTITKDIERNFKDEVRVMTTLRHPNVVLFMAASTKPPK--MCIVMEFMALGSLHDLLKN 875 Query 993 H---SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 I A + A Q +GM +LH+ HRDL + N+LLD VK+ DFGL K Sbjct 876 ELIPDIPFALKVKIAYQASKGMHFLHSSGITHRDLKSLNLLLDIKWNVKVSDFGLTKFKS 935 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYK--FYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + + G + W APE L E + Y SDV+SFG+ ++EL+T + P Sbjct 936 DVKSINPEKFAG--TIQWTAPEILSEDREVDYILSDVYSFGIIMWELIT-----RDQPYF 988 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 + IA ++V+R ++L R + P E L+ +CW + + RPTF Sbjct 989 GMSPAAIA---VSVIRDNYRPVISDQL-RSEVAP-EYIELLTSCWHFDPTIRPTF 1038 Score = 64.7 bits (156), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 61/256 (24%), Positives = 108/256 (42%), Gaps = 26/256 (10%) Query 630 GRDRGQELRVVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 G RG E V +K++ P DI F + +M+ + H ++ + P+ +V Sbjct 803 GTWRGTE--VAVKMISPDKTITKDIERNFKDEVRVMTTLRHPNVVLFMAASTKPPKMCIV 860 Query 687 TEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 E++ G L L+ E +P A K+ +A Q + + +L + + H ++ N+LL Sbjct 861 MEFMALGSLHDLLKNELIPDIPFALKVKIAYQASKGMHFLHSSGITHRDLKSLNLLL--- 917 Query 746 GLAEGTSPFIKLSDPGV-----GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800 +K+SD G+ + +++ E+ I W APE L D + F Sbjct 918 ----DIKWNVKVSDFGLTKFKSDVKSINPEKFAGTIQWTAPEILSEDREVDYILSDVYSF 973 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------CPQLATLTSQCLTYEP 853 G + E+ + P SP+ R + P S P+ L + C ++P Sbjct 974 GIIMWEL-ITRDQPYFGMSPAAIAVSVIRDNYRPVISDQLRSEVAPEYIELLTSCWHFDP 1032 Query 854 TQRPSFRTILRDLTRL 869 T RP+F I+ L+ L Sbjct 1033 TIRPTFLEIMTRLSNL 1048 Score = 44.3 bits (103), Expect = 0.010, Method: Compositional matrix adjust. Identities = 51/248 (21%), Positives = 103/248 (42%), Gaps = 35/248 (14%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 + + + +D +H L E + + ++ H ++ + G ++ P +VTEY+ G L Sbjct 1427 KFIKQKIDENH---LLGIREEIAFLKKLHHPNIITMVGASLKKPNICIVTEYMAKGNLRD 1483 Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFI 755 +R + K+ + +A +SYL + + ++H ++ NIL+ + + Sbjct 1484 AMRTCTPKLEWHQKIKILVNIAKGISYLHSFDPPIIHRDIKPSNILIDE-------NWNV 1536 Query 756 KLSDPGVGLGALSREERVER---IP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 K++D G + E + P W APE + + +D + FG + E+ Sbjct 1537 KIAD--FGFARIKEENAIMTRCGTPCWTAPEIIRN--DIYDEKVDVFSFGIVMWEV---- 1588 Query 812 EAPLQSRSPSEKEHFYQRQHRLPE---PSCPQ-----LATLTSQCLTYEPTQRPSFRTIL 863 L + P +F + + E P PQ A L +C + T+RP+ ++ Sbjct 1589 ---LTCKEPFIGANFMKITMDILEDVRPKIPQDCPEEFAKLMRKCWHAKSTKRPTMDDVI 1645 Query 864 RDLTRLQP 871 L + P Sbjct 1646 IVLAKFCP 1653 >sp|O00506|STK25_HUMAN Serine/threonine-protein kinase 25 OS=Homo sapiens OX=9606 GN=STK25 PE=1 SV=1 Length=426 Score = 97.1 bits (240), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 61/196 (31%), Positives = 99/196 (51%), Gaps = 9/196 (5%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 K+ +G+G FG+V Y ++ T E+VA+K + + +QEI +L + Sbjct 22 KLDRIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPY 77 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I +Y G + L ++MEY+ GS D L + + ++I +G+ YLH++ Sbjct 78 ITRYFGSYLKSTK--LWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSER 135 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ A NVLL VK+ DFG+A + + R FW APE +K+ + Sbjct 136 KIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQ---IKRNTFVGTPFWMAPEVIKQSAY 192 Query 1079 YYASDVWSFGVTLYEL 1094 + +D+WS G+T EL Sbjct 193 DFKADIWSLGITAIEL 208 Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 66/298 (22%), Positives = 123/298 (41%), Gaps = 60/298 (20%) Query 583 RVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 RVD +E+ T+L +G+G+ VY+G +D+ V V + Sbjct 13 RVDPEELFTKLDRIGKGSFGEVYKG--------------IDNHTKEV----------VAI 48 Query 642 KVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWL 699 K++D D + +++SQ ++ G ++ + ++ EY+ G LD+ Sbjct 49 KIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLL- 107 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + G + + + +++ L YL ++ +H ++ N+LL+ G +KL+D Sbjct 108 --KPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQG-------DVKLAD 158 Query 760 PGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 GV G L+ R V W+APE + A D W G T +E+ Sbjct 159 FGVA-GQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKA--DIWSLGITAIELA------ 209 Query 815 LQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ--------CLTYEPTQRPSFRTILR 864 + P+ H + +P+ S P L S+ CL +P RP+ + +L+ Sbjct 210 -KGEPPNSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLK 266 >sp|Q9ZUF4|RIPK_ARATH Serine/threonine-protein kinase RIPK OS=Arabidopsis thaliana OX=3702 GN=RIPK PE=1 SV=1 Length=462 Score = 97.1 bits (240), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 88/253 (35%), Positives = 123/253 (49%), Gaps = 24/253 (9%) Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD-------LGEGHFGKV- 911 R + D++ + L++ L+++ SD VF LK I LGEG FG V Sbjct 45 RLSILDMSNPSSNTLSEDLSIS--LAGSDLHVFTLAELKVITQSFSSTNFLGEGGFGPVH 102 Query 912 SLYCYDPTNDG-TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG-CCEDQ 969 + D G + VAVK L + HR W E+ L L H++++K G CCE Sbjct 103 KGFIDDKLRPGLKAQPVAVKLLDLEGLQGHRE-WLTEVMFLGQLKHKNLVKLIGYCCE-- 159 Query 970 GEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQH--YIHRDL 1024 E+ LV E++P GSL + L R S+ + + A G+ +LH I+RD Sbjct 160 -EEHRTLVYEFMPRGSLENQLFRRYSASLPWSTRMKIAHGAATGLQFLHEAENPVIYRDF 218 Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHE-YYRVREDGDSPVFWYAPECLKEYKFYYASD 1083 A N+LLD+D K+ DFGLAK PEG + + R G + APE + SD Sbjct 219 KASNILLDSDYTAKLSDFGLAKDGPEGDDTHVSTRVMGTQG--YAAPEYIMTGHLTARSD 276 Query 1084 VWSFGVTLYELLT 1096 V+SFGV L ELLT Sbjct 277 VYSFGVVLLELLT 289 Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 72/289 (25%), Positives = 121/289 (42%), Gaps = 41/289 (14%) Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 G G +G +DD+ L PG + V +K+LD + + Q+ H +L Sbjct 97 GFGPVHKGFIDDK--LRPGL---KAQPVAVKLLDLEGLQGHREWLTEVMFLGQLKHKNLV 151 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWL-RRERGHVPMAWKMVVAQQLASALSYL-ENKN 729 + G C +V E++ G L+ L RR +P + +M +A A+ L +L E +N Sbjct 152 KLIGYCCEEEHRTLVYEFMPRGSLENQLFRRYSASLPWSTRMKIAHGAATGLQFLHEAEN 211 Query 730 -LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIP-WLAPE 782 +++ + NILL A KLSD G+ ++ RV + APE Sbjct 212 PVIYRDFKASNILLDSDYTA-------KLSDFGLAKDGPEGDDTHVSTRVMGTQGYAAPE 264 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE---------HFYQRQHRL 833 + G L+ D + FG LLE+ + + RS E+ + ++ R+ Sbjct 265 YIMTG--HLTARSDVYSFGVVLLELLTGRRSVDKKRSSREQNLVDWARPMLNDPRKLSRI 322 Query 834 PEP---------SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 +P + ATL QCL++ P RP ++ L L+ +N Sbjct 323 MDPRLEGQYSETGARKAATLAYQCLSHRPKNRPCMSAVVSILNDLKDYN 371 >sp|P09560|RAF1_XENLA RAF proto-oncogene serine/threonine-protein kinase OS=Xenopus laevis OX=8355 GN=raf1 PE=2 SV=1 Length=638 Score = 98.2 bits (243), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 68/200 (34%), Positives = 101/200 (51%), Gaps = 17/200 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y G VAVK LK D P+ ++ E+ +LR H +I+ Sbjct 346 IGSGSFGTV----YKGKWHGD---VAVKILKVTDPTPEQLQAFRNEVAVLRKTRHVNILL 398 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ Sbjct 399 FMGY---MTKDNLAIVTQWCEGSSLYYHLHVLDTKFQMFQLIDIARQTAQGMDYLHAKNI 455 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EY 1076 IHRD+ + N+ L VKIGDFGLA +V E + W APE ++ Sbjct 456 IHRDMKSNNIFLHEGLTVKIGDFGLATVKTRWSGSQQV-EQLTGSILWMAPEVIRMQDNN 514 Query 1077 KFYYASDVWSFGVTLYELLT 1096 F + SDV+S+G+ LYEL+T Sbjct 515 PFSFQSDVYSYGIVLYELMT 534 Score = 57.0 bits (136), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 79/337 (23%), Positives = 133/337 (39%), Gaps = 59/337 (18%) Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615 G+ N I RG R S + + E+ S +G G+ VY+G+ Sbjct 315 GQEKNKIRARGQRDSSY--------YWEIIASEVMLSSRIGSGSFGTVYKGKWH------ 360 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675 G +LKV DP+ + AF +++ + H ++ G Sbjct 361 ------------------GDVAVKILKVTDPTPEQLQ-AFRNEVAVLRKTRHVNILLFMG 401 Query 676 VCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGN 734 + +N+ +VT++ E L L M + +A+Q A + YL KN++H + Sbjct 402 YMTK--DNLAIVTQWCEGSSLYYHLHVLDTKFQMFQLIDIARQTAQGMDYLHAKNIIHRD 459 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGA 788 + NI L EG + +K+ D G+ G+ E+ I W+APE + Sbjct 460 MKSNNIF-----LHEGLT--VKIGDFGLATVKTRWSGSQQVEQLTGSILWMAPEVIRMQD 512 Query 789 NS-LSTAMDKWGFGATLLEICFDGEAPLQS-RSPSEKEHFYQRQHRLPEPS-----CPQ- 840 N+ S D + +G L E+ GE P R + R +P+ S CP+ Sbjct 513 NNPFSFQSDVYSYGIVLYEL-MTGELPYSHIRDRDQIIFLVGRGGVVPDLSKLYKNCPKA 571 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 + L + + +RP F IL + LQ H+L + Sbjct 572 MKRLVADSIKKLRDERPLFPQILSSIELLQ-HSLPKI 607 >sp|P18160|SPLA_DICDI Dual specificity protein kinase splA OS=Dictyostelium discoideum OX=44689 GN=splA PE=1 SV=3 Length=2410 Score = 99.4 bits (246), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 88/297 (30%), Positives = 135/297 (45%), Gaps = 46/297 (15%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTLYHEH 958 + +G+G FG+V + T+ VA+K + D S ++ E+ IL L H + Sbjct 2119 QTIGKGFFGEVKRGYWRETD------VAIKIIYRDQFKTKSSLVMFQNEVGILSKLRHPN 2172 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ----LLLFAQQICEGMAYL 1014 ++++ G C GE +V E++ GSLR +L H L Q L A I +GM YL Sbjct 2173 VVQFLGACTAGGEDHHCIVTEWMGGGSLRQFLTDHFNLLEQNPHIRLKLALDIAKGMNYL 2232 Query 1015 HAQH--YIHRDLAARNVLLDN-------------DRLVKIGDFGLAKAVPEGHEYYRVRE 1059 H +HRDL++RN+LLD+ D KI DFGL++ E + Sbjct 2233 HGWTPPILHRDLSSRNILLDHNIDPKNPVVSSRQDIKCKISDFGLSRLKME-QASQMTQS 2291 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 G P + APE K SDV+S+G+ L+ELLT S P Q M Sbjct 2292 VGCIP--YMAPEVFKGDSNSEKSDVYSYGMVLFELLT----SDEP-----------QQDM 2334 Query 1120 TVLRLTELLE-RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 +++ L R P P + ++ CW++ RPTF+ +I LK + ++ Sbjct 2335 KPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQIIVHLKEMEDQ 2391 Score = 60.5 bits (145), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 62/255 (24%), Positives = 113/255 (44%), Gaps = 38/255 (15%) Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPEN--IMVTEYVEHGPLDVWLR------RERG 704 + F ++S++ H ++ G C G E+ +VTE++ G L +L + Sbjct 2156 VMFQNEVGILSKLRHPNVVQFLGACTAGGEDHHCIVTEWMGGGSLRQFLTDHFNLLEQNP 2215 Query 705 HVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFI------- 755 H+ ++ +A +A ++YL ++H ++ RNILL + +P + Sbjct 2216 HI----RLKLALDIAKGMNYLHGWTPPILHRDLSSRNILLDHN--IDPKNPVVSSRQDIK 2269 Query 756 -KLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 K+SD GL L E+ V IP++APE G +NS + D + +G L E+ Sbjct 2270 CKISD--FGLSRLKMEQASQMTQSVGCIPYMAPEVFKGDSNSEKS--DVYSYGMVLFELL 2325 Query 809 FDGEAPLQSRSPSEKEHFYQRQ-HRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRD 865 E P Q P + H + +R P P + + + +QC P RP+F+ I+ Sbjct 2326 TSDE-PQQDMKPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQIIVH 2384 Query 866 LTRLQPHNLADVLTV 880 L ++ ++ +V Sbjct 2385 LKEMEDQGVSSFASV 2399 >sp|Q23915|KINX_DICDI Probable serine/threonine-protein kinase kinX OS=Dictyostelium discoideum OX=44689 GN=kinX PE=3 SV=2 Length=1094 Score = 99.0 bits (245), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 77/279 (28%), Positives = 130/279 (47%), Gaps = 32/279 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ----EIDILRTLY 955 I ++G G FGKV Y G VA+K + +R ++ EI+ ++ Sbjct 25 ISEIGSGGFGKVFKGEY------LGAPVAIKKIHILPDDPNRVDLEKFLNREIETIKLFT 78 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--FAQQICEGMAY 1013 H ++I++ G E+ G L +V E + G L+ YL SI L L A + M+Y Sbjct 79 HPNVIQFVGISENNG--ILFIVTELIEGGDLQYYLKNQSIDLPWFLRANIALDVSLAMSY 136 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 LH++ +HRDL + N+L+D + +K+ DFG A+ V E + D+ W +PE + Sbjct 137 LHSKSIVHRDLKSTNLLVDKNWKIKVCDFGFARIVEEDNNKSMTICGTDN---WMSPEMI 193 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + SD++SFG+ L E++ S+ P ++ L E + R + Sbjct 194 TGLDYDERSDIFSFGIVLLEII-----SRVKPAPYMRDASFG--------LAEDIVRNQL 240 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +P CP + L NC + + RP+F+ + LK + Sbjct 241 IPT--DCPESLIDLTFNCCSVDPNNRPSFKEISQTLKQI 277 Score = 58.5 bits (140), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 56/234 (24%), Positives = 102/234 (44%), Gaps = 20/234 (9%) Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 DP+ D+ + +H ++ G+ +VTE +E G L +L+ + Sbjct 57 DPNRVDLEKFLNREIETIKLFTHPNVIQFVGISENNGILFIVTELIEGGDLQYYLKNQSI 116 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 +P + +A ++ A+SYL +K++VH ++ N+L+ + IK+ D G Sbjct 117 DLPWFLRANIALDVSLAMSYLHSKSIVHRDLKSTNLLVDKNWK-------IKVCD--FGF 167 Query 765 GALSREERVERIP------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE-APLQS 817 + E+ + + W++PE + G D + FG LLEI + AP Sbjct 168 ARIVEEDNNKSMTICGTDNWMSPEMITGL--DYDERSDIFSFGIVLLEIISRVKPAPYMR 225 Query 818 RSPSEKEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + R +P CP+ L LT C + +P RPSF+ I + L +++ Sbjct 226 DASFGLAEDIVRNQLIP-TDCPESLIDLTFNCCSVDPNNRPSFKEISQTLKQIK 278 >sp|Q54VC0|Y9865_DICDI Probable serine/threonine-protein kinase DDB_G0280461 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0280461 PE=3 SV=1 Length=418 Score = 96.3 bits (238), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 84/292 (29%), Positives = 131/292 (45%), Gaps = 40/292 (14%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW---KQEIDILRTLY-- 955 + +G F KV Y G V VK +K D S W K+EI IL+ L Sbjct 18 NEFSKGSFAKVYKGSY------YGNPVCVKVIKKDTLIDKES-WVFLKREIGILKNLLNQ 70 Query 956 -HEHIIKYKGCCEDQGEKS--LQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEG 1010 H++II++ G GEK L LV E + G L + L H I + + A+ I EG Sbjct 71 GHKNIIRFIGI----GEKDSLLFLVTELINGGDLGNILLDHKFHIPWSLRVKIAKDIAEG 126 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 M YLH++ +HRDL + N+LL + +KI DFG AK + + D + +P Sbjct 127 MEYLHSKQIMHRDLKSNNLLLGRNWTIKICDFGFAKEITIQNPLSMTICGTDE---FMSP 183 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E + ++ Y++D++SFG+ L EL+T + P + I + Q + Sbjct 184 EVILGIQYSYSADIYSFGMVLLELITRSKLDERLPQNNFD-IDYEELQNKI--------- 233 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182 P +CP E L C + + RP+F +++ L + K + P Sbjct 234 ------PSECPREFLELSMKCCNYDPNDRPSFTDIVQTLDQLAIKLVKETPD 279 Score = 69.7 bits (169), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 59/239 (25%), Positives = 113/239 (47%), Gaps = 23/239 (10%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 +L++Q H ++ G+ + +VTE + G L L + H+P + ++ +A+ +A Sbjct 66 NLLNQ-GHKNIIRFIGIGEKDSLLFLVTELINGGDLGNILLDHKFHIPWSLRVKIAKDIA 124 Query 720 SALSYLENKNLVHGNVCGRNILLAR---LGLAE-GTSPFIKLSDPGVGLGALSREERVER 775 + YL +K ++H ++ N+LL R + + + G + I + +P + + +E Sbjct 125 EGMEYLHSKQIMHRDLKSNNLLLGRNWTIKICDFGFAKEITIQNP-LSMTICGTDE---- 179 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--EHFYQRQHRL 833 +++PE + G S S D + FG LLE+ + L R P + + Q+++ Sbjct 180 --FMSPEVILGIQYSYSA--DIYSFGMVLLELI--TRSKLDERLPQNNFDIDYEELQNKI 233 Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA-SDPTV 891 P + L+ +C Y+P RPSF I++ L +L ++ PD P S P V Sbjct 234 PSECPREFLELSMKCCNYDPNDRPSFTDIVQTLDQLA----IKLVKETPDGPYPSTPIV 288 >sp|Q8VCT9|TESK2_MOUSE Dual specificity testis-specific protein kinase 2 OS=Mus musculus OX=10090 GN=Tesk2 PE=1 SV=1 Length=570 Score = 97.4 bits (241), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 77/282 (27%), Positives = 126/282 (45%), Gaps = 39/282 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G F +V + + +G+ V ALK + +R+ +E+ ++ L H +I+++ Sbjct 64 IGSGFFSEV----FKVRHRASGQ---VMALKMNTLSSNRANLLKEMQLMNRLSHPNILRF 116 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G C QG+ L + EY+ G+L L + + A I G++YLH + H Sbjct 117 MGVCVHQGQ--LHALTEYINSGNLEQLLDSDLYLPWTVRVKLAYDIAVGLSYLHFKGIFH 174 Query 1022 RDLAARNVLLDNDR---LVKIGDFGLAKAVPE---GHEYYRVREDGDSPVFWYAPECLKE 1075 RDL ++N L+ D + DFGLA+ +P+ G E V SP FW APE L++ Sbjct 175 RDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGREKLAVV---GSP-FWMAPEVLRD 230 Query 1076 YKFYYASDVWSFGVTLYELLT--HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + +DV+S+G+ L E++ D P T+ L A M Sbjct 231 EPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMV------------- 277 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 CP + L NC + RP+FE + LK + + Sbjct 278 ----GDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLKEIMSR 315 Score = 60.8 bits (146), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 63/251 (25%), Positives = 104/251 (41%), Gaps = 28/251 (11%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 R GQ + + + L + ++ + LM+++SH ++ GVCV + +TEY+ Sbjct 78 RASGQVMALKMNTLSSNRANL----LKEMQLMNRLSHPNILRFMGVCVHQGQLHALTEYI 133 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR------ 744 G L+ L + ++P ++ +A +A LSYL K + H ++ +N L+ R Sbjct 134 NSGNLEQLLDSDL-YLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYS 192 Query 745 -----LGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 GLAE K+ D +G L+ V W+APE L + D + Sbjct 193 AVVADFGLAE------KIPDASIGREKLA---VVGSPFWMAPEVL--RDEPYNEKADVFS 241 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQRPS 858 +G L EI +A +E + CP LT C +P RPS Sbjct 242 YGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVGDCPSDFLQLTFNCCNMDPKLRPS 301 Query 859 FRTILRDLTRL 869 F I + L + Sbjct 302 FEEIGKTLKEI 312 >sp|A8WYE4|PAR1_CAEBR Serine/threonine-protein kinase par-1 OS=Caenorhabditis briggsae OX=6238 GN=par-1 PE=3 SV=1 Length=1088 Score = 98.6 bits (244), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 70/208 (34%), Positives = 104/208 (50%), Gaps = 13/208 (6%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDI 950 H K ++ +G+G+F KV L + T G VA+K + K P +E+ I Sbjct 123 VHVGKYKLLKTIGKGNFAKVKLAKHVIT----GHEVAIKIIDKTALNPSSLQKLFREVKI 178 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICE 1009 ++ L H +I+K E E++L LV+EY G + DYL H + + +QI Sbjct 179 MKQLDHPNIVKLYQVMET--EQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS 236 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + YLH+++ IHRDL A N+LLD D +KI DFG + G++ G P + A Sbjct 237 AVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFC--GSPP--YAA 292 Query 1070 PECLKEYKFYYAS-DVWSFGVTLYELLT 1096 PE K+ DVWS GV LY L++ Sbjct 293 PELFSGKKYDGPEVDVWSLGVILYTLVS 320 Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 54/236 (23%), Positives = 99/236 (42%), Gaps = 22/236 (9%) Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K++D + + + + +M Q+ H ++ ++ V +V EY G + Sbjct 154 VAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVF 213 Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 +L H M K A+ Q+ SA+ YL +KN++H ++ N+LL + Sbjct 214 DYLV---AHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQ-------DMN 263 Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 IK++D G S +++ P+ APE G +D W G +L Sbjct 264 IKIADFGFS-NTFSLGNKLDTFCGSPPYAAPELF-SGKKYDGPEVDVWSLGV-ILYTLVS 320 Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 G P ++ E +E + ++R+P L + L P +R S I++D Sbjct 321 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKD 376 >sp|P53670|LIMK2_RAT LIM domain kinase 2 OS=Rattus norvegicus OX=10116 GN=Limk2 PE=2 SV=1 Length=638 Score = 97.8 bits (242), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 76/281 (27%), Positives = 125/281 (44%), Gaps = 38/281 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+ T+ TG+++ +K L C + + + E+ ++R+L H +++K+ Sbjct 337 LGKGFFGQA----IKVTHKATGKVMVMKEL-IRCDEETQKTFLTEVKVMRSLDHPNVLKF 391 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G +K L L+ EY+ G+L+D+L Q + FA+ I GMAYLH+ IH Sbjct 392 IGVL--YKDKKLNLLTEYIEGGTLKDFLRNVDPFPWQQKVRFAKGIASGMAYLHSMCIIH 449 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---------------- 1065 RDL + N L+ D+ V + DFGL++ + E + V + Sbjct 450 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRPPVEKAATKKRTLRKSDRKKRYTVVGN 509 Query 1066 -FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 +W APE L + DV+SFG+ L E++ + + L+ G L Sbjct 510 PYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDF-----GLNVKLFW 564 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + P CP + L C + E RP F L Sbjct 565 EKFV--------PTDCPPAFFPLAAICCKLEPESRPAFSKL 597 Score = 53.9 bits (128), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 61/248 (25%), Positives = 102/248 (41%), Gaps = 31/248 (13%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +V+K L + F +M + H ++ GV + + ++TEY+E G L + Sbjct 357 MVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDF 416 Query 699 LRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNIL-------------LA 743 LR P W+ V A+ +AS ++YL + ++H ++ N L L+ Sbjct 417 LRNVD---PFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLS 473 Query 744 RLGLAEGTSPFI-KLSDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWG 799 RL + E P + K + L R++R + W+APE L G S +D + Sbjct 474 RLIVEERKRPPVEKAATKKRTLRKSDRKKRYTVVGNPYWMAPEMLNG--KSYDETVDVFS 531 Query 800 FGATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854 FG L EI A P + F+++ +P P L + C EP Sbjct 532 FGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEK--FVPTDCPPAFFPLAAICCKLEPE 589 Query 855 QRPSFRTI 862 RP+F + Sbjct 590 SRPAFSKL 597 >sp|Q9TW45|PAR1_CAEEL Serine/threonine-protein kinase par-1 OS=Caenorhabditis elegans OX=6239 GN=par-1 PE=1 SV=1 Length=1192 Score = 98.6 bits (244), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 70/208 (34%), Positives = 104/208 (50%), Gaps = 13/208 (6%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDI 950 H K ++ +G+G+F KV L + T G VA+K + K P +E+ I Sbjct 165 VHVGKYKLLKTIGKGNFAKVKLAKHVIT----GHEVAIKIIDKTALNPSSLQKLFREVKI 220 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICE 1009 ++ L H +I+K E E++L LV+EY G + DYL H + + +QI Sbjct 221 MKQLDHPNIVKLYQVMET--EQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS 278 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + YLH+++ IHRDL A N+LLD D +KI DFG + G++ G P + A Sbjct 279 AVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTF--CGSPP--YAA 334 Query 1070 PECLKEYKFYYAS-DVWSFGVTLYELLT 1096 PE K+ DVWS GV LY L++ Sbjct 335 PELFSGKKYDGPEVDVWSLGVILYTLVS 362 Score = 47.8 bits (112), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 54/236 (23%), Positives = 99/236 (42%), Gaps = 22/236 (9%) Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K++D + + + + +M Q+ H ++ ++ V +V EY G + Sbjct 196 VAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVF 255 Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 +L H M K A+ Q+ SA+ YL +KN++H ++ N+LL + Sbjct 256 DYLV---AHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQ-------DMN 305 Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 IK++D G S +++ P+ APE G +D W G +L Sbjct 306 IKIADFGFS-NTFSLGNKLDTFCGSPPYAAPELF-SGKKYDGPEVDVWSLGV-ILYTLVS 362 Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 G P ++ E +E + ++R+P L + L P +R S I++D Sbjct 363 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKD 418 >sp|B4MR28|PTK7_DROWI Tyrosine-protein kinase-like otk OS=Drosophila willistoni OX=7260 GN=otk PE=3 SV=1 Length=1059 Score = 98.6 bits (244), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 69/258 (27%), Positives = 120/258 (47%), Gaps = 34/258 (13%) Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 +V VKAL Q +++++D+LR L H+ I++ G C ++ LV+EY G Sbjct 806 LVMVKALNKVKDEQACQEFRRQLDLLRALSHKGIVRLYGLCREKDPH--YLVLEYTDWGD 863 Query 986 LRDYL------------------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027 L+ +L P + +Q+L A QI GM ++ + HRDLA R Sbjct 864 LKQFLLATAGKVNTATTATSSTTPLPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATR 923 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 N ++ ++ +VK+ L K EY++ R + P+ W APEC++E ++ SD++S+ Sbjct 924 NCVISSEFIVKVSYPALCKD-KYSREYHKHR-NSLLPIRWLAPECIQEDEYTTKSDIFSY 981 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 GV ++EL +++ P I + Q L+ T + P + + Sbjct 982 GVVVWELFNQ--ATKLPHEDLTNEQVIEKSQDGTLKWT----------VAESTPESLKEI 1029 Query 1148 MKNCWETEASFRPTFENL 1165 + +CW RP+F L Sbjct 1030 LLSCWSVNPKQRPSFSQL 1047 Score = 55.5 bits (132), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 61/258 (24%), Positives = 105/258 (41%), Gaps = 39/258 (15%) Query 639 VVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V++K L+ + A F L+ +SH + ++G+C + +V EY + G L Sbjct 807 VMVKALNKVKDEQACQEFRRQLDLLRALSHKGIVRLYGLCREKDPHYLVLEYTDWGDLKQ 866 Query 698 WLRRERGHV--------------PMAWKMV--VAQQLASALSYLENKNLVHGNVCGRNIL 741 +L G V P+ V VA Q+A + + H ++ RN + Sbjct 867 FLLATAGKVNTATTATSSTTPLPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRNCV 926 Query 742 LARLGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAM 795 + +S FI K+S P + SRE R I WLAPEC+ + +T Sbjct 927 I--------SSEFIVKVSYPALCKDKYSREYHKHRNSLLPIRWLAPECIQ--EDEYTTKS 976 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH-----RLPEPSCPQLATLTSQCLT 850 D + +G + E+ F+ L + ++ + Q + E + L + C + Sbjct 977 DIFSYGVVVWEL-FNQATKLPHEDLTNEQVIEKSQDGTLKWTVAESTPESLKEILLSCWS 1035 Query 851 YEPTQRPSFRTILRDLTR 868 P QRPSF + L++ Sbjct 1036 VNPKQRPSFSQLGAALSK 1053 >sp|Q86AT8|SPKA_DICDI Stress-activated protein kinase alpha OS=Dictyostelium discoideum OX=44689 GN=spkA-1 PE=1 SV=1 Length=638 Score = 97.8 bits (242), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 80/297 (27%), Positives = 138/297 (46%), Gaps = 25/297 (8%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + + L+ LG G GKV Y G+ VA+K LK+ + +K+E Sbjct 344 NIINDNELEYTEKLGAGSSGKVYKGLY------RGKEVAIKVLKSMTESKEIEEFKKEFQ 397 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQI 1007 I+ + +H++ + G E L +VME GSL + +S IG + FA + Sbjct 398 IMSAIRSKHVVHFYGAV---LEPKLCMVMENCSRGSLYHVMDNNSLDIGWERTFRFAIET 454 Query 1008 CEGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 G+ LH +HRDL + N+L+++ +K+ DFGL++ + V+ G Sbjct 455 VRGIECLHKWDPPIVHRDLKSLNLLVNDKWEIKVCDFGLSRFNTGSNLETLVKMRG---T 511 Query 1066 FWY-APECLKEYKFYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVL 1122 F Y APE +F SDV+S V L+EL+T C + + P +++ L Q Sbjct 512 FAYCAPEVYYGEQFSGKSDVYSIAVILWELVTRCINGRYERPFSEYKNL------QHDFQ 565 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 + + ++ R P+ CP + L+++CW+ RPT +++ L T+ +Y+ Sbjct 566 IIIQTAKKNLRPTIPNACPESLVSLIQDCWDPNLENRPTCTDILSRLVTIENEYRSN 622 >sp|O54785|LIMK2_MOUSE LIM domain kinase 2 OS=Mus musculus OX=10090 GN=Limk2 PE=1 SV=2 Length=638 Score = 97.4 bits (241), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 77/281 (27%), Positives = 125/281 (44%), Gaps = 38/281 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+ T+ TG+++ +K L C + + + E+ ++R+L H +++K+ Sbjct 337 LGKGFFGQA----IKVTHKATGKVMVMKEL-IRCDEETQKTFLTEVKVMRSLDHPNVLKF 391 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G +K L L+ EY+ G+L+D+L Q + FA+ I GMAYLH+ IH Sbjct 392 IGVL--YKDKKLNLLTEYIEGGTLKDFLRSVDPFPWQQKVRFAKGISSGMAYLHSMCIIH 449 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE---------YYRVREDGDSPV------- 1065 RDL + N L+ D+ V + DFGL++ + E + R D Sbjct 450 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRPPVEKATTKKRTLRKSDRKKRYTVVGN 509 Query 1066 -FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 +W APE L + DV+SFG+ L E++ + + L+ G L Sbjct 510 PYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDF-----GLNVKLFW 564 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + P CP + L C + E RP F L Sbjct 565 EKFV--------PTDCPPAFFPLAAICCKLEPESRPAFSKL 597 Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 60/248 (24%), Positives = 102/248 (41%), Gaps = 31/248 (13%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +V+K L + F +M + H ++ GV + + ++TEY+E G L + Sbjct 357 MVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDF 416 Query 699 LRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNIL-------------LA 743 LR P W+ V A+ ++S ++YL + ++H ++ N L L+ Sbjct 417 LRSVD---PFPWQQKVRFAKGISSGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLS 473 Query 744 RLGLAEGTSPFI-KLSDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWG 799 RL + E P + K + L R++R + W+APE L G S +D + Sbjct 474 RLIVEERKRPPVEKATTKKRTLRKSDRKKRYTVVGNPYWMAPEMLNG--KSYDETVDVFS 531 Query 800 FGATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854 FG L EI A P + F+++ +P P L + C EP Sbjct 532 FGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEK--FVPTDCPPAFFPLAAICCKLEPE 589 Query 855 QRPSFRTI 862 RP+F + Sbjct 590 SRPAFSKL 597 >sp|P32562|CDC5_YEAST Cell cycle serine/threonine-protein kinase CDC5/MSD2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CDC5 PE=1 SV=1 Length=705 Score = 97.4 bits (241), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 67/198 (34%), Positives = 104/198 (53%), Gaps = 15/198 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQH-RSGWKQEIDILRTLYHEHII 960 LGEG F + C+ D +GE+ A K + KA + R EI I +++ H +I+ Sbjct 88 LGEGGFAR----CFQ-IKDDSGEIFAAKTVAKASIKSEKTRKKLLSEIQIHKSMSHPNIV 142 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA-QLLLFAQQICEGMAYLHAQHY 1019 ++ C ED + ++ +++E P GSL + L R + ++ F QIC + Y+H++ Sbjct 143 QFIDCFED--DSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFTTQICGAIKYMHSRRV 200 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL--KEYK 1077 IHRDL N+ D++ +KIGDFGLA + +E R +P + APE L K Sbjct 201 IHRDLKLGNIFFDSNYNLKIGDFGLAAVL--ANESERKYTICGTPN-YIAPEVLMGKHSG 257 Query 1078 FYYASDVWSFGVTLYELL 1095 + D+WS GV LY LL Sbjct 258 HSFEVDIWSLGVMLYALL 275 Score = 45.1 bits (105), Expect = 0.005, Method: Compositional matrix adjust. Identities = 49/216 (23%), Positives = 90/216 (42%), Gaps = 22/216 (10%) Query 661 LMSQV----SHTHLAFVHGV-CVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 L+S++ S +H V + C N+ ++ E +G L L+R + + Sbjct 126 LLSEIQIHKSMSHPNIVQFIDCFEDDSNVYILLEICPNGSLMELLKRRKVLTEPEVRFFT 185 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 Q + A+ Y+ ++ ++H ++ NI ++ +K+ D G+ + ER Sbjct 186 TQ-ICGAIKYMHSRRVIHRDLKLGNIFF-------DSNYNLKIGDFGLAAVLANESERKY 237 Query 775 RI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE-KEHFYQR 829 I ++APE L G + S +D W G L + G+ P Q+R + E R Sbjct 238 TICGTPNYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLI-GKPPFQARDVNTIYERIKCR 296 Query 830 QHRLP--EPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 P +P + L L+ +P +RPS I+ Sbjct 297 DFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIM 332 >sp|Q9I9E0|TAOK3_CHICK Serine/threonine-protein kinase TAO3 OS=Gallus gallus OX=9031 GN=TAOK3 PE=2 SV=2 Length=898 Score = 97.8 bits (242), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 74/203 (36%), Positives = 104/203 (51%), Gaps = 23/203 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956 + ++G G FG V Y TN T E+VAVK + + G Q W+ +E+ L+ L H Sbjct 27 LHEIGHGSFGAV----YFATNSHTNEVVAVKKM-SYSGKQTNEKWQDIIKEVKFLQQLKH 81 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014 + I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL Sbjct 82 PNTIEYKGCY--LKEHTAWLVMEYC-LGSASDMLEVHKKPLQEVEIAAITHGALQGLAYL 138 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071 H+ IHRD+ A N+LL VK+ DFG A V + + +P +W APE Sbjct 139 HSHCKIHRDIKAGNILLTEPGQVKLADFGSASIVSPANSFV------GTP-YWMAPEVIL 191 Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094 + E ++ DVWS G+T EL Sbjct 192 AMDEGQYDGKVDVWSLGITCIEL 214 >sp|Q55EI8|Y9956_DICDI Probable serine/threonine-protein kinase DDB_G0268876 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0268876 PE=3 SV=1 Length=1385 Score = 98.2 bits (243), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 79/260 (30%), Positives = 121/260 (47%), Gaps = 25/260 (10%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 G +AVK + + E I+ L H++I+ G G+ + LV +Y Sbjct 779 GYEIAVKQFNEEELGFSEREFHSEATIMSVLRHDNIVHCVGGSAQPGK--MYLVCDYYSR 836 Query 984 GSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 GSL + + L A+++ A Q+ +GM YLH+ IHRDL N+L+D D ++I D Sbjct 837 GSLYSVITANICPLSNARIVHLALQVAKGMNYLHSLGIIHRDLKPGNLLIDQDWNIRISD 896 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDS 1100 FGL++ V R+ + +P + A E LK Y +DV+SF L+E C S Sbjct 897 FGLSRVVDN-----RMTKTVGTPCYM-AVEVLKGLTDYSQQADVYSFAFVLWE----CIS 946 Query 1101 SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 Q P F ++ I+ +LE R P PD C E L+ CW + RP Sbjct 947 RQIPYKDFAQIQWISM----------VLEDSFRPPIPDSCLPEFRDLITMCWTSNPDDRP 996 Query 1161 TFENLIPILKTVHEKYQGQA 1180 +F+ +I L+ + K Q Q Sbjct 997 SFQQIITYLENLRLKMQDQG 1016 Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 55/233 (24%), Positives = 102/233 (44%), Gaps = 17/233 (7%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F+ A++MS + H ++ G + + +V +Y G L + + A + + Sbjct 799 FHSEATIMSVLRHDNIVHCVGGSAQPGKMYLVCDYYSRGSLYSVITANICPLSNARIVHL 858 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 A Q+A ++YL + ++H ++ N+L+ + I++SD G+ +R + Sbjct 859 ALQVAKGMNYLHSLGIIHRDLKPGNLLIDQ-------DWNIRISDFGLSRVVDNRMTKTV 911 Query 775 RIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE-KEHFYQRQHR 832 P ++A E L G + S D + F L E C + P + + + + R Sbjct 912 GTPCYMAVEVLKGLTD-YSQQADVYSFAFVLWE-CISRQIPYKDFAQIQWISMVLEDSFR 969 Query 833 LPEP-SC-PQLATLTSQCLTYEPTQRPSFRTILRDLT----RLQPHNLADVLT 879 P P SC P+ L + C T P RPSF+ I+ L ++Q + +LT Sbjct 970 PPIPDSCLPEFRDLITMCWTSNPDDRPSFQQIITYLENLRLKMQDQGIYQILT 1022 >sp|Q0WRY5|PBL7_ARATH Probable serine/threonine-protein kinase PBL7 OS=Arabidopsis thaliana OX=3702 GN=PBL7 PE=1 SV=1 Length=378 Score = 94.7 bits (234), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 77/212 (36%), Positives = 109/212 (51%), Gaps = 19/212 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG+V Y T + A+K L + G Q + E+ +L L+H +++ Sbjct 79 IGEGGFGRV----YKGYLASTSQTAAIKQLDHN-GLQGNREFLVEVLMLSLLHHPNLVNL 133 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017 G C D G++ L LV EY+PLGSL D+L S G L + A +G+ YLH + Sbjct 134 IGYCAD-GDQRL-LVYEYMPLGSLEDHLHDISPGKQPLDWNTRMKIAAGAAKGLEYLHDK 191 Query 1018 HY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 I+RDL N+LLD+D K+ DFGLAK P G + + V + APE Sbjct 192 TMPPVIYRDLKCSNILLDDDYFPKLSDFGLAKLGPVGDKSH-VSTRVMGTYGYCAPEYAM 250 Query 1075 EYKFYYASDVWSFGVTLYELLT---HCDSSQS 1103 + SDV+SFGV L E++T DSS+S Sbjct 251 TGQLTLKSDVYSFGVVLLEIITGRKAIDSSRS 282 Score = 54.3 bits (129), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 63/237 (27%), Positives = 99/237 (42%), Gaps = 35/237 (15%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KMVVAQQ 717 ++S + H +L + G C G + ++V EY+ G L+ L G P+ W +M +A Sbjct 121 MLSLLHHPNLVNLIGYCADGDQRLLVYEYMPLGSLEDHLHDISPGKQPLDWNTRMKIAAG 180 Query 718 LASALSYLENKNL---VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERV 773 A L YL +K + ++ ++ NILL F KLSD G+ LG + + V Sbjct 181 AAKGLEYLHDKTMPPVIYRDLKCSNILL-------DDDYFPKLSDFGLAKLGPVGDKSHV 233 Query 774 E-RIPWLAPECLPGGANS--LSTAMDKWGFGATLLEICFDGEAPLQSRSPSE-------- 822 R+ C P A + L+ D + FG LLEI +A SRS E Sbjct 234 STRVMGTYGYCAPEYAMTGQLTLKSDVYSFGVVLLEIITGRKAIDSSRSTGEQNLVAWAR 293 Query 823 -----KEHFYQR-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + F Q Q + P Q + + C+ +P RP ++ L+ L Sbjct 294 PLFKDRRKFSQMADPMLQGQYPPRGLYQALAVAAMCVQEQPNLRPLIADVVTALSYL 350 >sp|Q14680|MELK_HUMAN Maternal embryonic leucine zipper kinase OS=Homo sapiens OX=9606 GN=MELK PE=1 SV=3 Length=651 Score = 97.4 bits (241), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 71/204 (35%), Positives = 108/204 (53%), Gaps = 12/204 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 +Y + +G G F KV L C+ T GEMVA+K + + K EI+ L+ L Sbjct 9 KYYELHETIGTGGFAKVKLACHILT----GEMVAIKIMDKNTLGSDLPRIKTEIEALKNL 64 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAY 1013 H+HI + E + + +V+EY P G L DY+ + + + + +QI +AY Sbjct 65 RHQHICQLYHVLETANK--IFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAY 122 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +H+Q Y HRDL N+L D +K+ DFGL A P+G++ Y ++ S + + APE L Sbjct 123 VHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC-AKPKGNKDYHLQTCCGS-LAYAAPE-L 179 Query 1074 KEYKFYYAS--DVWSFGVTLYELL 1095 + K Y S DVWS G+ LY L+ Sbjct 180 IQGKSYLGSEADVWSMGILLYVLM 203 >sp|Q27324|RYK1_DROME Tyrosine-protein kinase Drl OS=Drosophila melanogaster OX=7227 GN=drl PE=2 SV=1 Length=610 Score = 97.1 bits (240), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 94/390 (24%), Positives = 163/390 (42%), Gaps = 58/390 (15%) Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQ--HRLPEPSCPQLATLTSQCLTYEPTQRPSF 859 +TL+ I + + P R PS H + RLP S +T + T P++ Sbjct 258 STLILIAYCAKGP-SKRHPSNGVHLIKTSSFQRLPTIS----STAHNSIYVCPSTITPTY 312 Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY----LKKIRD-----LGEGHFGK 910 T+ R + +P F++R ++K R + EG+FG+ Sbjct 313 ATLTRPFREYE----------------HEPEEFNRRLQELTVQKCRVRLSCLVQEGNFGR 356 Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970 + Y+ + V VK + + QE +L H +++ G + Sbjct 357 IYRGTYNDCQE-----VLVKTVAQHASQLQVNLLLQESMMLYEASHPNVLSVLGISIEDY 411 Query 971 EKSLQLVMEYVPLGSLRDYL--PRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 L + +L+ +L P + S+ Q +L Q+ M +LH IH+D+AA Sbjct 412 ATPFVLYAATGSVRNLKSFLQDPSYARSVTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAA 471 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD-SPVFWYAPECLKEYKFYYASDVW 1085 RN ++D+ VK+ D L++ + G Y DG+ P+ W + E L++ + SDVW Sbjct 472 RNCVIDDQLRVKLTDSALSRDLFPGD--YNSLGDGEYRPIKWLSLEALQKSHYNEGSDVW 529 Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 SFGV ++E+ T L + ++ + L+ G RL +P CP E++ Sbjct 530 SFGVLMWEMCT--------------LGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELF 575 Query 1146 HLMKNCWETEASFRPTFENLIPILKTVHEK 1175 +M CW + + RP+F L L H + Sbjct 576 TIMAYCWASMPAERPSFSQLQICLSEFHTQ 605 Score = 64.3 bits (155), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 47/167 (28%), Positives = 76/167 (46%), Gaps = 27/167 (16%) Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 V +++ QLA A+ +L N ++H ++ RN ++ +KL+D Sbjct 440 VTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVI-------DDQLRVKLTD-----S 487 Query 766 ALSRE-----------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 ALSR+ I WL+ E L + + D W FG + E+C G+ P Sbjct 488 ALSRDLFPGDYNSLGDGEYRPIKWLSLEALQ--KSHYNEGSDVWSFGVLMWEMCTLGKLP 545 Query 815 LQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 P E EH+ + +RL +P +CP +L T+ + C P +RPSF Sbjct 546 YAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSF 592 >sp|Q86HG9|Y9871_DICDI Probable serine/threonine-protein kinase DDB_G0271682 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0271682 PE=3 SV=2 Length=1024 Score = 97.8 bits (242), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 78/282 (28%), Positives = 129/282 (46%), Gaps = 38/282 (13%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEH 958 I+ +G G G+V Y + G VAVK + K+ + +++E+ IL+ L H + Sbjct 363 IKKIGSGACGEVCQY------EWKGTPVAVKTIFKSLLRKDKKEEFEKEVSILKCLRHPN 416 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH 1015 ++ + G C G +L ++ EY+ GSLRD L + + L+ + + +GM YLH Sbjct 417 VVLFMGTCLLNG--NLAIITEYLNRGSLRDVLTTMNKSELSLSVKVKMLIDVAQGMNYLH 474 Query 1016 AQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRDL + N+L+DN+ VK+ DFGL++ + G G + W APE Sbjct 475 TYSPPIIHRDLKSLNLLVDNNFNVKVSDFGLSRFISGGIGSSAKTFCG--TLSWIAPEVF 532 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + DV+SFG+ L+E+LTH P+ + + ++ Sbjct 533 NGSGYTTKVDVYSFGIVLWEILTH-----KQPSGNISATSLGHPEL-------------- 573 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 P CP L+K C RP F ++ LK ++ + Sbjct 574 ---PSNCPQSFSDLIKECCNRNPDQRPNFSQILLKLKLMYNQ 612 Score = 64.3 bits (155), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 55/218 (25%), Positives = 94/218 (43%), Gaps = 27/218 (12%) Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQ 717 S++ + H ++ G C+ ++TEY+ G L DV + + ++ K+ + Sbjct 406 VSILKCLRHPNVVLFMGTCLLNGNLAIITEYLNRGSLRDVLTTMNKSELSLSVKVKMLID 465 Query 718 LASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGALSR 769 +A ++YL + ++H + L L L + +K+SD G+ G+G+ S Sbjct 466 VAQGMNYLHTYSPPIIHRD-------LKSLNLLVDNNFNVKVSDFGLSRFISGGIGS-SA 517 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 + + W+APE G +T +D + FG L EI L + PS Sbjct 518 KTFCGTLSWIAPEVFNGSG--YTTKVDVYSFGIVLWEI-------LTHKQPSGNISATSL 568 Query 830 QHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866 H +CPQ + L +C P QRP+F IL L Sbjct 569 GHPELPSNCPQSFSDLIKECCNRNPDQRPNFSQILLKL 606 Score = 40.8 bits (94), Expect = 0.083, Method: Compositional matrix adjust. Identities = 32/140 (23%), Positives = 65/140 (46%), Gaps = 19/140 (14%) Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP-ECLKEYKFYYASDVWSFGVTL 1091 N+ +K+ DFGL++ + +E G+ F Y+P E L + SD++S + L Sbjct 887 NEIKIKVHDFGLSRFNTQENEESLKEIKGN---FLYSPPELLSLNTYSNKSDIYSLSIVL 943 Query 1092 YELLTHC-DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP-RP---DKCPCEVYH 1146 YEL C + P ++T+ +++ + +L RP + P E+ Sbjct 944 YELFETCLTKTYKKPYH----------EVTLDFDFQIIHKTSKLNLRPTISNNMPNEISK 993 Query 1147 LMKNCWETEASFRPTFENLI 1166 +++ W +++ RP+ + +I Sbjct 994 ILQQGWFSDSVLRPSLDTII 1013 >sp|Q8RWW0|ALE2_ARATH Receptor-like serine/threonine-protein kinase ALE2 OS=Arabidopsis thaliana OX=3702 GN=ALE2 PE=1 SV=1 Length=744 Score = 97.4 bits (241), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 74/200 (37%), Positives = 102/200 (51%), Gaps = 15/200 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LGEG FG+V + DGT VAVK L D + R + E+++L L+H +++ Sbjct 353 RVLGEGGFGRVYQGSME---DGT--EVAVKLLTRDNQNRDRE-FIAEVEMLSRLHHRNLV 406 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ--- 1017 K G C + ++ L+ E V GS+ +L ++ L A G+AYLH Sbjct 407 KLIGICIEG--RTRCLIYELVHNGSVESHLHEGTLDWDARLKIALGAARGLAYLHEDSNP 464 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKEY 1076 IHRD A NVLL++D K+ DFGLA+ EG ++ R G F Y APE Sbjct 465 RVIHRDFKASNVLLEDDFTPKVSDFGLAREATEGSQHISTRVMG---TFGYVAPEYAMTG 521 Query 1077 KFYYASDVWSFGVTLYELLT 1096 SDV+S+GV L ELLT Sbjct 522 HLLVKSDVYSYGVVLLELLT 541 >sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapiens OX=9606 GN=LIMK2 PE=1 SV=1 Length=638 Score = 97.1 bits (240), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 76/281 (27%), Positives = 124/281 (44%), Gaps = 38/281 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+ T+ TG+++ +K L C + + + E+ ++R+L H +++K+ Sbjct 337 LGKGFFGQA----IKVTHKATGKVMVMKEL-IRCDEETQKTFLTEVKVMRSLDHPNVLKF 391 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G +K L L+ EY+ G+L+D+L Q + FA+ I GMAYLH+ IH Sbjct 392 IGVL--YKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAYLHSMCIIH 449 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE---------YYRVREDGDSPV------- 1065 RDL + N L+ D+ V + DFGL++ + E + R D Sbjct 450 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGN 509 Query 1066 -FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 +W APE L + D++SFG+ L E++ + + L+ G L Sbjct 510 PYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDF-----GLNVKLFW 564 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + P CP + L C E RP F L Sbjct 565 EKFV--------PTDCPPAFFPLAAICCRLEPESRPAFSKL 597 Score = 53.9 bits (128), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 61/248 (25%), Positives = 102/248 (41%), Gaps = 31/248 (13%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +V+K L + F +M + H ++ GV + + ++TEY+E G L + Sbjct 357 MVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDF 416 Query 699 LRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNIL-------------LA 743 L R P W+ V A+ +AS ++YL + ++H ++ N L L+ Sbjct 417 L---RSMDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLS 473 Query 744 RLGLAE-GTSPFIKLSDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWG 799 RL + E +P K + L R++R + W+APE L G S +D + Sbjct 474 RLIVEERKRAPMEKATTKKRTLRKNDRKKRYTVVGNPYWMAPEMLNG--KSYDETVDIFS 531 Query 800 FGATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854 FG L EI A P + F+++ +P P L + C EP Sbjct 532 FGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEK--FVPTDCPPAFFPLAAICCRLEPE 589 Query 855 QRPSFRTI 862 RP+F + Sbjct 590 SRPAFSKL 597 >sp|Q9ZNQ8|PERK4_ARATH Proline-rich receptor-like protein kinase PERK4 OS=Arabidopsis thaliana OX=3702 GN=PERK4 PE=1 SV=1 Length=633 Score = 96.7 bits (239), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 69/201 (34%), Positives = 104/201 (52%), Gaps = 18/201 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V +G+ VAVK+LKA G R ++ E+DI+ ++H +++ Sbjct 290 LGQGGFGYVHKGVLP-----SGKEVAVKSLKAGSGQGERE-FQAEVDIISRVHHRYLVSL 343 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL---LLFAQQICEGMAYLHAQ-- 1017 G C G++ LV E+VP +L +L ++ + + L A +G+AYLH Sbjct 344 VGYCIADGQR--MLVYEFVPNKTLEYHLHGKNLPVMEFSTRLRIALGAAKGLAYLHEDCH 401 Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075 IHRD+ + N+LLD + + DFGLAK + + + R G F Y APE Sbjct 402 PRIIHRDIKSANILLDFNFDAMVADFGLAKLTSDNNTHVSTRVMG---TFGYLAPEYASS 458 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 K SDV+S+GV L EL+T Sbjct 459 GKLTEKSDVFSYGVMLLELIT 479 Score = 38.5 bits (88), Expect = 0.47, Method: Compositional matrix adjust. Identities = 59/260 (23%), Positives = 98/260 (38%), Gaps = 44/260 (17%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K L F ++S+V H +L + G C+ + ++V E+V + L+ Sbjct 309 VAVKSLKAGSGQGEREFQAEVDIISRVHHRYLVSLVGYCIADGQRMLVYEFVPNKTLEYH 368 Query 699 LRRERGHV-PMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILL--------ARLG 746 L + V + ++ +A A L+YL ++H ++ NILL A G Sbjct 369 LHGKNLPVMEFSTRLRIALGAAKGLAYLHEDCHPRIIHRDIKSANILLDFNFDAMVADFG 428 Query 747 LAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 LA+ TS V +G +LAPE G L+ D + +G LLE Sbjct 429 LAKLTSDNNTHVSTRV-MGTFG---------YLAPEYASSG--KLTEKSDVFSYGVMLLE 476 Query 807 IC----------------FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ----LATLTS 846 + D PL +R+ + RL PQ + T + Sbjct 477 LITGKRPVDNSITMDDTLVDWARPLMARALEDGNFNELADARLEGNYNPQEMARMVTCAA 536 Query 847 QCLTYEPTQRPSFRTILRDL 866 + + +RP I+R L Sbjct 537 ASIRHSGRKRPKMSQIVRAL 556 >sp|Q9CAL8|PEK13_ARATH Proline-rich receptor-like protein kinase PERK13 OS=Arabidopsis thaliana OX=3702 GN=PERK13 PE=1 SV=1 Length=710 Score = 97.1 bits (240), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 72/201 (36%), Positives = 102/201 (51%), Gaps = 18/201 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG C G++VAVK LK G R +K E++I+ ++H H++ Sbjct 359 LGEGGFG-----CVYKGKLNDGKLVAVKQLKVGSGQGDRE-FKAEVEIISRVHHRHLVSL 412 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 G C E+ L+ EYVP +L +L R + A+ + A +G+AYLH Sbjct 413 VGYCIADSER--LLIYEYVPNQTLEHHLHGKGRPVLEWARRVRIAIGSAKGLAYLHEDCH 470 Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075 IHRD+ + N+LLD++ ++ DFGLAK + R G F Y APE + Sbjct 471 PKIIHRDIKSANILLDDEFEAQVADFGLAKLNDSTQTHVSTRVMG---TFGYLAPEYAQS 527 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 K SDV+SFGV L EL+T Sbjct 528 GKLTDRSDVFSFGVVLLELIT 548 Score = 43.9 bits (102), Expect = 0.011, Method: Compositional matrix adjust. Identities = 50/184 (27%), Positives = 77/184 (42%), Gaps = 37/184 (20%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F ++S+V H HL + G C+ E +++ EYV + L+ L +G + W ++ Sbjct 394 FKAEVEIISRVHHRHLVSLVGYCIADSERLLIYEYVPNQTLEHHL-HGKGRPVLEWARRV 452 Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPG 761 +A A L+YL ++H ++ NILL A GLA KL+D Sbjct 453 RIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDDEFEAQVADFGLA-------KLND-- 503 Query 762 VGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 S + V +LAPE G L+ D + FG LLE+ G P+ Sbjct 504 ------STQTHVSTRVMGTFGYLAPEYAQSG--KLTDRSDVFSFGVVLLEL-ITGRKPVD 554 Query 817 SRSP 820 P Sbjct 555 QYQP 558 >sp|F1QGZ6|MELK_DANRE Maternal embryonic leucine zipper kinase OS=Danio rerio OX=7955 GN=melk PE=2 SV=1 Length=676 Score = 96.7 bits (239), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 73/197 (37%), Positives = 105/197 (53%), Gaps = 14/197 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G F KV L + TGE VA+K + K D G K EI+ ++ L H+H+ + Sbjct 19 IGSGGFAKVKL----GRHKLTGEKVAIKIMEKKDLG-DDLPRVKIEIEAMKNLSHQHVCR 73 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 E + + +V+EY P G L DY+ + + + +F +QI +AY+H+Q Y Sbjct 74 LYHVIETTSK--IYMVLEYCPGGELFDYIIAKDRLSEEETRVFFRQIISALAYVHSQGYA 131 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDL N+L+D D +K+ DFGL A P+G + + SP + APE L + K Y Sbjct 132 HRDLKPENLLIDEDHNLKLIDFGLC-AKPKGGLGFELLTCCGSPAY-AAPE-LIQGKAYI 188 Query 1081 AS--DVWSFGVTLYELL 1095 S DVWS GV LY LL Sbjct 189 GSEADVWSMGVLLYALL 205 >sp|Q10407|MKH1_SCHPO MAP kinase kinase kinase mkh1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=mkh1 PE=3 SV=1 Length=1116 Score = 97.4 bits (241), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 73/216 (34%), Positives = 112/216 (52%), Gaps = 41/216 (19%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG------------WKQEIDI 950 +G G +GKV L N TGE++AVK ++ PQ +G EI + Sbjct 831 IGNGTYGKVFL----AMNINTGELIAVKQVEI---PQTINGRHDQLRKDIVDSINAEISM 883 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS----LRDYLPRHSIGLAQLLLF-AQ 1005 + L H +I++Y G ++ E + + +EYV GS LR+Y P QL+ F ++ Sbjct 884 IADLDHLNIVQYLGF--EKTETDISIFLEYVSGGSIGRCLRNYGPFEE----QLVRFVSR 937 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD--- 1062 Q+ G++YLH++ IHRDL A N+L+D D + KI DFG++K H D + Sbjct 938 QVLYGLSYLHSKGIIHRDLKADNLLIDFDGVCKISDFGISK-----HSDNVYDNDANLSM 992 Query 1063 -SPVFWYAPECL-KEYKFYYAS-DVWSFGVTLYELL 1095 +FW APE + +++ Y A DVWS G + E+L Sbjct 993 QGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEML 1028 Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 54/240 (23%), Positives = 94/240 (39%), Gaps = 38/240 (16%) Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D DI + S+++ + H ++ G + + EYV G + LR Sbjct 867 DQLRKDIVDSINAEISMIADLDHLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLR---N 923 Query 705 HVPMAWKMV--VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + P ++V V++Q+ LSYL +K ++H ++ N+L+ G+ K+SD G+ Sbjct 924 YGPFEEQLVRFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDFDGVC-------KISDFGI 976 Query 763 GLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 + + + I W+APE + S +D W G +LE+ L Sbjct 977 SKHSDNVYDNDANLSMQGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEM-------LA 1029 Query 817 SRSPSEKEHFYQRQHRL-------PEPS------CPQLATLTSQCLTYEPTQRPSFRTIL 863 R P + Q +L P PS P+ + C T RP+ +L Sbjct 1030 GRRPWSTDEAIQAMFKLGTEKKAPPIPSELVSQVSPEAIQFLNACFTVNADVRPTAEELL 1089 >sp|Q6DD27|TAOK3_XENLA Serine/threonine-protein kinase TAO3 OS=Xenopus laevis OX=8355 GN=taok3 PE=2 SV=1 Length=896 Score = 97.4 bits (241), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 85/265 (32%), Positives = 125/265 (47%), Gaps = 40/265 (15%) Query 878 LTVNPDSP----ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933 L +PD+ DP +R + ++G G FG V Y TN T E+VAVK + Sbjct 5 LVKDPDNADLFCKEDP----ERIFVDLHEIGHGSFGAV----YFATNSTTNEIVAVKKM- 55 Query 934 ADCGPQHRSGWK---QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 + G Q W+ +E+ L+ L H + I+YKGC + + LVMEY LGS D L Sbjct 56 SYSGKQMNEKWQDIIKEVKFLQQLKHPNTIEYKGCY--LKDHTAWLVMEYC-LGSASDLL 112 Query 991 PRHSIGLAQLLLFA--QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 H L ++ + A +G+AYLH+ + IHRD+ A N+LL VK+ DFG A Sbjct 113 EVHKKPLQEVEIAAITHGALQGLAYLHSHNMIHRDIKAGNILLTEPGQVKLADFGSASKS 172 Query 1049 PEGHEYYRVREDGDSPVFWYAPE---CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + +P +W APE + E ++ D+WS G+T EL + + PP Sbjct 173 SPANSFV------GTP-YWMAPEVILAMDEGQYDGKIDIWSLGITCIEL-----AERKPP 220 Query 1106 ----TKFLELIGIAQGQMTVLRLTE 1126 L IAQ + L+ E Sbjct 221 LFNMNAMSALYHIAQNESPTLQSNE 245 Score = 36.6 bits (83), Expect = 2.0, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 8/88 (9%) Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781 L+YL + N++H ++ NILL G +KL+D G + V W+AP Sbjct 135 LAYLHSHNMIHRDIKAGNILLTEPGQ-------VKLADFGSASKSSPANSFVGTPYWMAP 187 Query 782 EC-LPGGANSLSTAMDKWGFGATLLEIC 808 E L +D W G T +E+ Sbjct 188 EVILAMDEGQYDGKIDIWSLGITCIELA 215 >sp|Q8H186|PBL1_ARATH Probable serine/threonine-protein kinase PBL1 OS=Arabidopsis thaliana OX=3702 GN=PBL1 PE=1 SV=1 Length=389 Score = 94.4 bits (233), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 92/288 (32%), Positives = 135/288 (47%), Gaps = 31/288 (11%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +GEG FG V D PT +G ++AVK L D HR W EI+ L L H Sbjct 67 VGEGGFGCVFRGWLDETTLTPTKSSSGLVIAVKRLNPDGFQGHRE-WLTEINYLGQLSHP 125 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSL---------RDYLPRHSIGLAQLLLFAQQIC 1008 +++K G C + ++ LV E++ GSL +D+ P I ++ L A Sbjct 126 NLVKLIGYCLEDEQR--LLVYEFMHKGSLENHLFANGNKDFKPLSWILRIKVALDA---A 180 Query 1009 EGMAYLHAQ--HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE-YYRVREDGDSPV 1065 +G+A+LH+ I+RD+ A N+LLD+D K+ DFGLA+ P G + Y R G Sbjct 181 KGLAFLHSDPVKVIYRDIKASNILLDSDFNAKLSDFGLARDGPMGEQSYVSTRVMG---T 237 Query 1066 FWY-APECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR 1123 F Y APE + SDV+SFGV L ELL + + P K L+ A+ +T R Sbjct 238 FGYAAPEYVSTGHLNARSDVYSFGVVLLELLCGRQALDHNRPAKEQNLVDWARPYLTSRR 297 Query 1124 LTELL--ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 L+ R +P+ + + C E RPT + ++ L Sbjct 298 KVLLIVDTRLNSQYKPEGA-VRLASIAVQCLSFEPKSRPTMDQVVRAL 344 Score = 65.1 bits (157), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 69/280 (25%), Positives = 124/280 (44%), Gaps = 44/280 (16%) Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 DE L P + L + +K L+P + + + Q+SH +L + G C+ + Sbjct 81 DETTLTPTKS-SSGLVIAVKRLNPDGFQGHREWLTEINYLGQLSHPNLVKLIGYCLEDEQ 139 Query 683 NIMVTEYVEHGPLD--VWLRRERGHVPMAW--KMVVAQQLASALSYLENK--NLVHGNVC 736 ++V E++ G L+ ++ + P++W ++ VA A L++L + +++ ++ Sbjct 140 RLLVYEFMHKGSLENHLFANGNKDFKPLSWILRIKVALDAAKGLAFLHSDPVKVIYRDIK 199 Query 737 GRNILLARLGLAEGTSPF-IKLSDPGVGL-GALSREERVER-----IPWLAPECLPGGAN 789 NILL S F KLSD G+ G + + V + APE + G Sbjct 200 ASNILL--------DSDFNAKLSDFGLARDGPMGEQSYVSTRVMGTFGYAAPEYVSTG-- 249 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-------HFYQRQHRL--------- 833 L+ D + FG LLE+ +A +R E+ + R+ L Sbjct 250 HLNARSDVYSFGVVLLELLCGRQALDHNRPAKEQNLVDWARPYLTSRRKVLLIVDTRLNS 309 Query 834 ---PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 PE + +LA++ QCL++EP RP+ ++R L +LQ Sbjct 310 QYKPEGAV-RLASIAVQCLSFEPKSRPTMDQVVRALVQLQ 348 >sp|A9RVK2|M3K1B_PHYPA Mitogen-activated protein kinase kinase kinase 1b OS=Physcomitrium patens OX=3218 GN=MEKK1b PE=2 SV=2 Length=764 Score = 97.1 bits (240), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 77/270 (29%), Positives = 122/270 (45%), Gaps = 33/270 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQ---EIDILRTLYHEH 958 +G G FG V Y+ D G AVK + D G + KQ EI +L + H + Sbjct 437 IGSGTFGSV----YEGI-DNNGMFFAVKEVSLKDQGKVGQEAIKQLEHEIALLSDIQHPN 491 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I++Y G D ++ L + +E V GSL ++ Q+ + +QI G+ YLH + Sbjct 492 IVQYLGTERD--DEKLYIFLELVSKGSLASLYKKYYFVYDQVRAYTKQILSGLKYLHDRK 549 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ N+L+D + +VK+ DFG+AK V + + + W APE + + Sbjct 550 IIHRDIKCANILVDTNGVVKLADFGMAKQV----DKLGLLKSFMGSAHWMAPEVVNPKRQ 605 Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ-GQMTVLRLTELLERGERLPR 1136 Y + +D+WS G T+ E+ T G A G++ + + GE Sbjct 606 YNFLADIWSLGCTVLEMAT----------------GDAPFGELECHSVLWKVGNGEGPLI 649 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 PD E+ + C E RPT + L+ Sbjct 650 PDDLEDEMKDFISKCLEVTVGNRPTCDMLL 679 Score = 41.2 bits (95), Expect = 0.077, Method: Compositional matrix adjust. Identities = 57/228 (25%), Positives = 99/228 (43%), Gaps = 42/228 (18%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 +G GT +VYEG ++ +G M V +D+G+ + +K L+ H+IAL Sbjct 437 IGSGTFGSVYEG---IDNNG------MFFAVKEVSLKDQGKVGQEAIKQLE---HEIAL- 483 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 +S + H ++ G + + E V G L ++ + V Sbjct 484 -------LSDIQHPNIVQYLGTERDDEKLYIFLELVSKGSLASLYKKYY----FVYDQVR 532 Query 715 A--QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-----LGAL 767 A +Q+ S L YL ++ ++H ++ NIL+ G+ +KL+D G+ LG L Sbjct 533 AYTKQILSGLKYLHDRKIIHRDIKCANILVDTNGV-------VKLADFGMAKQVDKLGLL 585 Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 + + W+APE + + D W G T+LE+ G+AP Sbjct 586 --KSFMGSAHWMAPEVV-NPKRQYNFLADIWSLGCTVLEMA-TGDAPF 629 >sp|Q32L23|LIMK2_BOVIN LIM domain kinase 2 OS=Bos taurus OX=9913 GN=LIMK2 PE=2 SV=1 Length=638 Score = 96.7 bits (239), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 76/281 (27%), Positives = 125/281 (44%), Gaps = 38/281 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+ T+ TG+++ + L C + + + E+ ++R+L H +++K+ Sbjct 337 LGKGFFGQA----IKVTHKATGKVMVMNEL-IRCDEETQKTFLTEVKVMRSLDHPNVLKF 391 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G +K L L+ EY+ G+L+D+L Q + FA+ I GMAYLH+ IH Sbjct 392 IGVL--YKDKKLNLLTEYIEGGTLKDFLRNVDPFPWQQKVRFAKGIASGMAYLHSMCIIH 449 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE---------YYRVREDGDSPV------- 1065 RDL + N L+ D+ V + DFGL++ + E + R D Sbjct 450 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKKPPVEKATTKKRTLRKSDRKKRYTVVGN 509 Query 1066 -FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 +W APE L + DV+SFG+ L E++ + + L+ G L Sbjct 510 PYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDF-----GLNVKLFW 564 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + P++CP + L C E RP F L Sbjct 565 EKFV--------PEECPPAFFPLAAICCRLEPESRPAFSKL 597 Score = 54.7 bits (130), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 61/248 (25%), Positives = 102/248 (41%), Gaps = 31/248 (13%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +V+ L + F +M + H ++ GV + + ++TEY+E G L + Sbjct 357 MVMNELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDF 416 Query 699 LRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNIL-------------LA 743 LR P W+ V A+ +AS ++YL + ++H ++ N L L+ Sbjct 417 LRNVD---PFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLS 473 Query 744 RLGLAEGTSPFI-KLSDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWG 799 RL + E P + K + L R++R + W+APE L G S +D + Sbjct 474 RLIVEERKKPPVEKATTKKRTLRKSDRKKRYTVVGNPYWMAPEMLNG--KSYDETVDVFS 531 Query 800 FGATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854 FG L EI A P + F+++ +PE P L + C EP Sbjct 532 FGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEK--FVPEECPPAFFPLAAICCRLEPE 589 Query 855 QRPSFRTI 862 RP+F + Sbjct 590 SRPAFSKL 597 >sp|A6ZU08|TOS3_YEAS7 Serine/threonine-protein kinase TOS3 OS=Saccharomyces cerevisiae (strain YJM789) OX=307796 GN=TOS3 PE=3 SV=1 Length=560 Score = 95.9 bits (237), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 70/224 (31%), Positives = 108/224 (48%), Gaps = 40/224 (18%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW-----------KQEIDIL 951 LG G +GKV L + GTG +VA+K L + RSG+ QEI+++ Sbjct 56 LGNGQYGKVKL----ARDLGTGALVAIKILNRF---EKRSGYSLQLKVENPRVNQEIEVM 108 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA----QLLLFAQQ- 1006 + +HE++++ D + LV+EY G ++ + P + + + +L F Q Sbjct 109 KRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVK-WCPENKMEIKAVGPSILTFQQSR 167 Query 1007 -----ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG-------HEY 1054 + G+ YLH+Q HRD+ N+L+ ++ VKI DFG+A + G HE Sbjct 168 KVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQ 227 Query 1055 YRVREDGDSPVFWYAPECL---KEYKFYYASDVWSFGVTLYELL 1095 +P F +APE KEY A D+WS GVT+Y LL Sbjct 228 LLKSRALGTPAF-FAPELCSTEKEYSCSSAIDIWSLGVTIYCLL 270 Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 47/198 (24%), Positives = 82/198 (41%), Gaps = 41/198 (21%) Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP-----ENIMVTEYVEHGPL 695 ++V+ HH+ + YE +++ T + V C RGP EN M + V GP Sbjct 105 IEVMKRCHHENVVELYE---ILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAV--GPS 159 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 + ++ R V + S L YL ++ + H ++ N+L++ G + Sbjct 160 ILTFQQSRK---------VVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGT-------V 203 Query 756 KLSDPGVGLGALSREERVERI-------------PWLAPE-CLPGGANSLSTAMDKWGFG 801 K+SD GV + + ++ + APE C S S+A+D W G Sbjct 204 KISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLG 263 Query 802 ATLLEICFDGEAPLQSRS 819 T+ + F G+ P + S Sbjct 264 VTIYCLLF-GKLPFNANS 280 >sp|C0LGD7|Y1684_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g06840 OS=Arabidopsis thaliana OX=3702 GN=At1g06840 PE=1 SV=2 Length=953 Score = 97.1 bits (240), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 87/290 (30%), Positives = 138/290 (48%), Gaps = 39/290 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961 +G+G +GKV Y T G+G +VA+K +A G Q + EI++L L+H +++ Sbjct 631 IGQGGYGKV----YKGT-LGSGTVVAIK--RAQEGSLQGEKEFLTEIELLSRLHHRNLVS 683 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI------CEGMAYLH 1015 G C+++GE+ LV EY+ G+LRD + S+ L + L FA ++ +G+ YLH Sbjct 684 LLGFCDEEGEQ--MLVYEYMENGTLRDNI---SVKLKEPLDFAMRLRIALGSAKGILYLH 738 Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVP----EGHEYYRVREDGDSPVFWY 1068 + HRD+ A N+LLD+ K+ DFGL++ P EG V + Sbjct 739 TEANPPIFHRDIKASNILLDSRFTAKVADFGLSRLAPVPDMEGISPQHVSTVVKGTPGYL 798 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT---KFLELIGIAQGQMTVLRLT 1125 PE ++ SDV+S GV L EL T P T + I IA ++L Sbjct 799 DPEYFLTHQLTDKSDVYSLGVVLLELFT----GMQPITHGKNIVREINIAYESGSILSTV 854 Query 1126 ELLERGERLPR-PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + +R+ PD+C + L C E RP+ ++ L+ + E Sbjct 855 D-----KRMSSVPDECLEKFATLALRCCREETDARPSMAEVVRELEIIWE 899 Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust. Identities = 73/295 (25%), Positives = 116/295 (39%), Gaps = 50/295 (17%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 + +GQG VY+G L GSG K E L +G++ Sbjct 629 TQIGQGGYGKVYKGTL---GSGTVVAIKRAQEGSL-----QGEK---------------- 664 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWK 711 F L+S++ H +L + G C E ++V EY+E+G L D + + + A + Sbjct 665 -EFLTEIELLSRLHHRNLVSLLGFCDEEGEQMLVYEYMENGTLRDNISVKLKEPLDFAMR 723 Query 712 MVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGL 764 + +A A + YL N + H ++ NILL A+ G S + D G+ Sbjct 724 LRIALGSAKGILYLHTEANPPIFHRDIKASNILLDSRFTAKVADFGLSRLAPVPDME-GI 782 Query 765 GALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS------ 817 V+ P +L PE + L+ D + G LLE+ F G P+ Sbjct 783 SPQHVSTVVKGTPGYLDPEYFL--THQLTDKSDVYSLGVVLLEL-FTGMQPITHGKNIVR 839 Query 818 ------RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 S S +R +P+ + ATL +C E RPS ++R+L Sbjct 840 EINIAYESGSILSTVDKRMSSVPDECLEKFATLALRCCREETDARPSMAEVVREL 894 >sp|P43637|TOS3_YEAST Serine/threonine-protein kinase TOS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TOS3 PE=1 SV=1 Length=560 Score = 95.9 bits (237), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 70/224 (31%), Positives = 108/224 (48%), Gaps = 40/224 (18%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW-----------KQEIDIL 951 LG G +GKV L + GTG +VA+K L + RSG+ QEI+++ Sbjct 56 LGNGQYGKVKL----ARDLGTGALVAIKILNRF---EKRSGYSLQLKVENPRVNQEIEVM 108 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA----QLLLFAQQ- 1006 + +HE++++ D + LV+EY G ++ + P + + + +L F Q Sbjct 109 KRCHHENVVELYEILNDPESTKVYLVLEYCSRGPVK-WCPENKMEIKAVGPSILTFQQSR 167 Query 1007 -----ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG-------HEY 1054 + G+ YLH+Q HRD+ N+L+ ++ VKI DFG+A + G HE Sbjct 168 KVVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGTVKISDFGVAMSTATGSTNIQSSHEQ 227 Query 1055 YRVREDGDSPVFWYAPECL---KEYKFYYASDVWSFGVTLYELL 1095 +P F +APE KEY A D+WS GVT+Y LL Sbjct 228 LLKSRALGTPAF-FAPELCSTEKEYSCSSAIDIWSLGVTIYCLL 270 Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 47/198 (24%), Positives = 82/198 (41%), Gaps = 41/198 (21%) Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP-----ENIMVTEYVEHGPL 695 ++V+ HH+ + YE +++ T + V C RGP EN M + V GP Sbjct 105 IEVMKRCHHENVVELYE---ILNDPESTKVYLVLEYCSRGPVKWCPENKMEIKAV--GPS 159 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 + ++ R V + S L YL ++ + H ++ N+L++ G + Sbjct 160 ILTFQQSRK---------VVLDVVSGLEYLHSQGITHRDIKPSNLLISSNGT-------V 203 Query 756 KLSDPGVGLGALSREERVERI-------------PWLAPE-CLPGGANSLSTAMDKWGFG 801 K+SD GV + + ++ + APE C S S+A+D W G Sbjct 204 KISDFGVAMSTATGSTNIQSSHEQLLKSRALGTPAFFAPELCSTEKEYSCSSAIDIWSLG 263 Query 802 ATLLEICFDGEAPLQSRS 819 T+ + F G+ P + S Sbjct 264 VTIYCLLF-GKLPFNANS 280 >sp|Q6NU21|TAO1A_XENLA Serine/threonine-protein kinase TAO1-A OS=Xenopus laevis OX=8355 GN=taok1-a PE=2 SV=1 Length=1001 Score = 97.1 bits (240), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 78/245 (32%), Positives = 120/245 (49%), Gaps = 32/245 (13%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDI 950 ++ +R++G G FG V + +D + T E+VA+K + + G Q W+ +E+ Sbjct 25 EKLFSDLREIGHGSFGAV-YFAHDAS---TREVVAIKKM-SYSGKQSNEKWQDIVKEVKF 79 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQIC 1008 L+ + H + I+YKGC E + LVMEY LGS D L H L ++ + A Sbjct 80 LQRIKHPNSIEYKGCY--LREHTAWLVMEYC-LGSASDLLEVHKKPLQEIEIAAITHGAL 136 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +G+AYLH+ + IHRD+ A N+LL VK+ DFG A + + +P +W Sbjct 137 QGLAYLHSHNLIHRDIKAGNILLTEPGQVKLADFGSASIASPANSFV------GTP-YWM 189 Query 1069 APE---CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP----TKFLELIGIAQGQMTV 1121 APE + E ++ DVWS G+T EL + + PP L IAQ + Sbjct 190 APEVILAMDEGQYDGKVDVWSLGITCIEL-----AERKPPLFNMNAMSALYHIAQNESPT 244 Query 1122 LRLTE 1126 L+ E Sbjct 245 LQSNE 249 Score = 37.4 bits (85), Expect = 1.0, Method: Compositional matrix adjust. Identities = 27/88 (31%), Positives = 38/88 (43%), Gaps = 8/88 (9%) Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781 L+YL + NL+H ++ NILL G +KL+D G A V W+AP Sbjct 139 LAYLHSHNLIHRDIKAGNILLTEPGQ-------VKLADFGSASIASPANSFVGTPYWMAP 191 Query 782 EC-LPGGANSLSTAMDKWGFGATLLEIC 808 E L +D W G T +E+ Sbjct 192 EVILAMDEGQYDGKVDVWSLGITCIELA 219 >sp|Q9LZF8|PCRK2_ARATH Serine/threonine-protein kinase PCRK2 OS=Arabidopsis thaliana OX=3702 GN=PCRK2 PE=1 SV=1 Length=420 Score = 94.7 bits (234), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 69/203 (34%), Positives = 101/203 (50%), Gaps = 11/203 (5%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG FG V D + ++ VAVK L G Q W E++ L + H +++K Sbjct 87 IGEGGFGCVFWGTIKNLEDPSKKIEVAVKQL-GKRGLQGHKEWVTEVNFLGVVEHSNLVK 145 Query 962 YKGCCEDQGEKSLQ--LVMEYVPLGSLRDYL-PRHSIGLAQ--LLLFAQQICEGMAYLHA 1016 G C + E+ +Q LV EY+P S+ +L PR L L AQ G+ YLH Sbjct 146 LLGHCAEDDERGIQRLLVYEYMPNQSVEFHLSPRSPTVLTWDLRLRIAQDAARGLTYLHE 205 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + I RD + N+LLD + K+ DFGLA+ P + V D + + APE + Sbjct 206 EMDFQIIFRDFKSSNILLDENWTAKLSDFGLARLGPSPGSSH-VSTDVVGTMGYAAPEYI 264 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 + + SDVW +GV +YEL+T Sbjct 265 QTGRLTSKSDVWGYGVFIYELIT 287 Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 60/266 (23%), Positives = 111/266 (42%), Gaps = 33/266 (12%) Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV----RGPENIMVT 687 D +++ V +K L + + + V H++L + G C RG + ++V Sbjct 105 DPSKKIEVAVKQLGKRGLQGHKEWVTEVNFLGVVEHSNLVKLLGHCAEDDERGIQRLLVY 164 Query 688 EYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILL 742 EY+ + ++ L R + W ++ +AQ A L+YL + ++ + NILL Sbjct 165 EYMPNQSVEFHLS-PRSPTVLTWDLRLRIAQDAARGLTYLHEEMDFQIIFRDFKSSNILL 223 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 A+ + + P G +S + V + + APE + G L++ D WG+G Sbjct 224 DENWTAKLSDFGLARLGPSPGSSHVS-TDVVGTMGYAAPEYIQTG--RLTSKSDVWGYGV 280 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQ---------RQHRL-PEP---------SCPQLAT 843 + E+ G PL P ++ + R+ RL +P S +LA Sbjct 281 FIYEL-ITGRRPLDRNKPKGEQKLLEWVRPYLSDTRRFRLIVDPRLEGKYMIKSVQKLAV 339 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869 + + CLT RP +L +T++ Sbjct 340 VANLCLTRNAKARPKMSEVLEMVTKI 365 >sp|P52497|SNF1_CANAX Carbon catabolite-derepressing protein kinase OS=Candida albicans OX=5476 GN=SNF1 PE=2 SV=2 Length=620 Score = 96.3 bits (238), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 77/219 (35%), Positives = 111/219 (51%), Gaps = 17/219 (8%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQ 939 P PA++P RY + ++ LGEG FGKV L + GTG+ VA+K + K Sbjct 39 PIDPAANPANRIGRY-QILKTLGEGSFGKVKL----AQHLGTGQKVALKIINRKTLAKSD 93 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLA 998 + ++EI LR L H HIIK + + E + +V+E+ L DY+ R + Sbjct 94 MQGRVEREISYLRLLRHPHIIKLYDVIKSKDE--IIMVIEFAG-KELFDYIVQRGKMPED 150 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 + F QQI + Y H +HRDL N+LLD+ VKI DFGL+ + +G+ ++ Sbjct 151 EARRFFQQIIAAVEYCHRHKIVHRDLKPENLLLDDQLNVKIADFGLSNIMTDGN---FLK 207 Query 1059 EDGDSPVFWYAPECLKEYKFYYA--SDVWSFGVTLYELL 1095 SP + APE + K Y DVWS GV LY +L Sbjct 208 TSCGSPNYMPAPEVISG-KLYAGPEVDVWSAGVILYVML 245 Score = 34.3 bits (77), Expect = 9.0, Method: Compositional matrix adjust. Identities = 49/241 (20%), Positives = 89/241 (37%), Gaps = 21/241 (9%) Query 634 GQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 G +V LK+++ + D+ S + + H H+ ++ V E IMV E+ Sbjct 74 GTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEFA 133 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 D + +RG +P QQ+ +A+ Y +VH ++ N+LL Sbjct 134 GKELFDYIV--QRGKMPEDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLLL-------D 184 Query 751 TSPFIKLSDPGVGLGALSREERVERIPWLAPECLPG-----GANSLSTAMDKWGFGATLL 805 +K++D GL + + + +P +P G +D W G +L Sbjct 185 DQLNVKIAD--FGLSNIMTDGNFLKTSCGSPNYMPAPEVISGKLYAGPEVDVWSAG-VIL 241 Query 806 EICFDGEAPLQSR-SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + G P P+ + + LP L ++ L P R + I+ Sbjct 242 YVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSAGAKHLLTRMLVVNPLNRITIHEIME 301 Query 865 D 865 D Sbjct 302 D 302 >sp|Q3TYD6|LMTK2_MOUSE Serine/threonine-protein kinase LMTK2 OS=Mus musculus OX=10090 GN=Lmtk2 PE=1 SV=3 Length=1471 Score = 97.1 bits (240), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 86/283 (30%), Positives = 132/283 (47%), Gaps = 49/283 (17%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG-EMVAVKALKADCGPQHRSGWKQEIDILR 952 + L I+++G G FGKV L T GT V VK LK P+ + + + + Sbjct 133 RHSLNYIQEIGSGWFGKVLL---GETYTGTSVARVIVKELKVSASPKEQDTFLKSGEPYY 189 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009 L H ++++ G C + LV E+ LG L+ YL H G +Q +L + CE Sbjct 190 ILQHPNVLQCVGQCVEA--IPYLLVFEFCDLGDLKAYLHNEQEHVRGDSQTMLLQRMACE 247 Query 1010 ---GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED----GD 1062 G+A +H H++H DLA RN L +D VK+GD+G+ + R +ED D Sbjct 248 IAAGLAAMHKLHFLHSDLALRNCYLTSDLNVKVGDYGIG--------FSRYKEDYIETDD 299 Query 1063 SPVF---WYAPECLKEYKFYYA-------SDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 VF W APE + ++ S++WS GVTL+EL + + P +L Sbjct 300 KKVFPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVTLWELFNN---AAQPYANLSDLD 356 Query 1113 GIAQGQMTVLRLTELLERGERLPRPD-KCPCEV--YHLMKNCW 1152 + Q V+R ER +LP+P + P Y +++ CW Sbjct 357 VLNQ----VIR-----ERDMKLPKPQLEQPYSDRWYEVLQFCW 390 >sp|F4IS56|ILK1_ARATH Integrin-linked protein kinase 1 OS=Arabidopsis thaliana OX=3702 GN=ILK1 PE=1 SV=1 Length=479 Score = 95.1 bits (235), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 71/259 (27%), Positives = 115/259 (44%), Gaps = 22/259 (8%) Query 923 TGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 G V+VK L D P+ + ++ E+ +L + H ++I++ G + +V+EY Sbjct 215 NGTRVSVKILDKDSYSDPERINAFRHELTLLEKVRHPNVIQFVGAVTQN--IPMMIVVEY 272 Query 981 VPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRL 1036 P G L YL + + ++ L FA I GM YLH IH DL +N+LLD Sbjct 273 NPKGDLSVYLQKKGRLSPSKALRFALDIARGMNYLHECKPDPIIHCDLKPKNILLDRGGQ 332 Query 1037 VKIGDFGLAKAVPEGHEYYRV---REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 +KI FG+ + + +V + D ++ APE K+ F D SFGV LYE Sbjct 333 LKISGFGMIRLSKISQDKAKVANHKAHIDLSNYYIAPEVYKDEIFDLRVDAHSFGVILYE 392 Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 + P + + + +G+ V + + P ++ L++ CW Sbjct 393 ITEGVPVFHPRPPEEVARMMCLEGKRPVFKT-----------KSRSYPPDIKELIEKCWH 441 Query 1154 TEASFRPTFENLIPILKTV 1172 EA RPTF +I L + Sbjct 442 PEAGIRPTFSEIIIRLDKI 460 Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust. Identities = 58/247 (23%), Positives = 102/247 (41%), Gaps = 19/247 (8%) Query 638 RVVLKVLDPSHH---DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 RV +K+LD + + AF +L+ +V H ++ G + ++V EY G Sbjct 218 RVSVKILDKDSYSDPERINAFRHELTLLEKVRHPNVIQFVGAVTQNIPMMIVVEYNPKGD 277 Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLG-LAEG 750 L V+L++ +G + + + A +A ++YL ++H ++ +NILL R G L Sbjct 278 LSVYLQK-KGRLSPSKALRFALDIARGMNYLHECKPDPIIHCDLKPKNILLDRGGQLKIS 336 Query 751 TSPFIKLSDPGVGLGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 I+LS ++ + + ++APE L +D FG L EI Sbjct 337 GFGMIRLSKISQDKAKVANHKAHIDLSNYYIAPEVYKDEIFDLR--VDAHSFGVILYEIT 394 Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLP------EPSCPQLATLTSQCLTYEPTQRPSFRTI 862 +G R P E + + P P + L +C E RP+F I Sbjct 395 -EGVPVFHPRPPEEVARMMCLEGKRPVFKTKSRSYPPDIKELIEKCWHPEAGIRPTFSEI 453 Query 863 LRDLTRL 869 + L ++ Sbjct 454 IIRLDKI 460 >sp|Q5R4F3|TAOK3_PONAB Serine/threonine-protein kinase TAO3 OS=Pongo abelii OX=9601 GN=TAOK3 PE=2 SV=1 Length=898 Score = 96.7 bits (239), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 73/203 (36%), Positives = 102/203 (50%), Gaps = 23/203 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956 + ++G G FG V Y TN T E+VA+K + + G Q W+ +E+ LR L H Sbjct 27 LHEIGHGSFGAV----YFATNAHTNEVVAIKKM-SYSGKQTHEKWQDILKEVKFLRQLKH 81 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014 + I+YKGC E + LVMEY LGS D L H L ++ + A G+AYL Sbjct 82 PNTIEYKGCY--LKEHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALHGLAYL 138 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071 H+ IHRD+ A N+LL VK+ DFG A + + +P +W APE Sbjct 139 HSHALIHRDIKAGNILLTEPGQVKLADFGSASVASPANSFV------GTP-YWMAPEVIL 191 Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094 + E ++ DVWS G+T EL Sbjct 192 AMDEGQYDGKVDVWSLGITCIEL 214 Score = 36.6 bits (83), Expect = 1.8, Method: Compositional matrix adjust. Identities = 47/204 (23%), Positives = 72/204 (35%), Gaps = 22/204 (11%) Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781 L+YL + L+H ++ NILL G +KL+D G A V W+AP Sbjct 135 LAYLHSHALIHRDIKAGNILLTEPGQ-------VKLADFGSASVASPANSFVGTPYWMAP 187 Query 782 EC-LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--C 838 E L +D W G T +E+ A + S H Q + + Sbjct 188 EVILAMDEGQYDGKVDVWSLGITCIELAERKPALFNMNAMSALYHIAQNDSPTLQSNEWT 247 Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898 CL P +RP+ +LR H+ V D P +R Sbjct 248 DSFRRFVDYCLQKIPQERPTSAELLR-------HDF-----VRRDRPLRVLIDLIQRTKD 295 Query 899 KIRDLGEGHFGKVSLYCYDPTNDG 922 +R+L + K+ + T +G Sbjct 296 AVRELDNLQYRKMKKILFQETRNG 319 >sp|Q9M0T3|MP3K3_ARATH Mitogen-activated protein kinase kinase kinase 3 OS=Arabidopsis thaliana OX=3702 GN=MEKK3 PE=2 SV=1 Length=560 Score = 95.9 bits (237), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 72/271 (27%), Positives = 122/271 (45%), Gaps = 34/271 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQ---EIDILRTLYHEH 958 LG G + V Y+ ++ G+ AVK + D G Q + +Q EI +L L H++ Sbjct 309 LGRGSYASV----YEAISED-GDFFAVKEVSLLDKGIQAQECIQQLEGEIALLSQLQHQN 363 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I++Y+G +D + L + +E V GS++ R+ + + L+ +QI G+ YLH + Sbjct 364 IVRYRGTAKDVSK--LYIFLELVTQGSVQKLYERYQLSYTVVSLYTRQILAGLNYLHDKG 421 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 ++HRD+ N+L+D + VK+ DFGLA+A + +FW APE + Sbjct 422 FVHRDIKCANMLVDANGTVKLADFGLAEA-----SKFNDIMSCKGTLFWMAPEVINRKDS 476 Query 1079 Y---YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 +D+WS G T+ E+ T I + ++ + RG Sbjct 477 DGNGSPADIWSLGCTVLEMCTG---------------QIPYSDLKPIQAAFKIGRGTLPD 521 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 PD + H + C + RPT L+ Sbjct 522 VPDTLSLDARHFILTCLKVNPEERPTAAELL 552 Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 53/214 (25%), Positives = 92/214 (43%), Gaps = 25/214 (12%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 +L+SQ+ H ++ G + + E V G V ER + + +Q+ Sbjct 354 ALLSQLQHQNIVRYRGTAKDVSKLYIFLELVTQG--SVQKLYERYQLSYTVVSLYTRQIL 411 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER---- 775 + L+YL +K VH ++ N+L+ A GT +KL+D GL S+ + Sbjct 412 AGLNYLHDKGFVHRDIKCANMLVD----ANGT---VKLAD--FGLAEASKFNDIMSCKGT 462 Query 776 IPWLAPECLP-GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834 + W+APE + ++ + D W G T+LE+C G+ P P + + R Sbjct 463 LFWMAPEVINRKDSDGNGSPADIWSLGCTVLEMC-TGQIPYSDLKPIQAAF---KIGRGT 518 Query 835 EPSCPQLATLTSQ-----CLTYEPTQRPSFRTIL 863 P P +L ++ CL P +RP+ +L Sbjct 519 LPDVPDTLSLDARHFILTCLKVNPEERPTAAELL 552 >sp|Q54DF2|MRKA_DICDI Probable serine/threonine-protein kinase MARK-A OS=Dictyostelium discoideum OX=44689 GN=mrkA PE=3 SV=1 Length=1060 Score = 97.1 bits (240), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 67/201 (33%), Positives = 105/201 (52%), Gaps = 14/201 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEH 958 I+ +G G FGKV L + E VA+K + K P+ ++E+ I++ L+H + Sbjct 112 IKTIGRGQFGKVKLGYHKKI---PNEKVAIKIINKGKLDPETLKMVQREVRIMKLLHHPN 168 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQ 1017 II+ E ++L L+MEY G + D++ H + +Q F QI + Y H++ Sbjct 169 IIRLYEVIE--TSRALYLIMEYAGEGEVMDFMIAHGVLTESQARTFFTQIVSAINYCHSK 226 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL--KE 1075 +HRDL N+LLD +R +KI DFGL+ G ++ SP + +PE + KE Sbjct 227 RAVHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGS---YLKTFCGSPTYA-SPELILRKE 282 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 Y + DVWS GV L+ L+T Sbjct 283 YNG-PSVDVWSMGVVLFVLVT 302 >sp|P08458|SPS1_YEAST Sporulation-specific protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SPS1 PE=1 SV=2 Length=490 Score = 95.1 bits (235), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 67/200 (34%), Positives = 102/200 (51%), Gaps = 19/200 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G+FG V Y + T E+VA+K + + + QEI L L I Y Sbjct 24 IGRGNFGDV----YKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNY 79 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GL--AQLLLFAQQICEGMAYLHAQHY 1019 + + S+ +VMEY GS D L R + GL ++ ++ G+ YLH Q Sbjct 80 IATMLE--DVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRK 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVFWYAPE--CLKE 1075 IHRD+ A N+LL+ + +VK+GDFG++ GH ++ D +P +W APE C + Sbjct 138 IHRDIKAANILLNEEGMVKLGDFGVS-----GHIRSTLKRDTFVGTP-YWMAPEVVCCEV 191 Query 1076 YKFYYASDVWSFGVTLYELL 1095 + +D+WS G+T YELL Sbjct 192 DGYNEKADIWSLGITTYELL 211 Score = 51.2 bits (121), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 58/243 (24%), Positives = 93/243 (38%), Gaps = 23/243 (9%) Query 632 DRGQELRVVLKVLDPSHHD-----IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 DR + V +KV++ H D +A + A L S + ++A + +V Sbjct 37 DRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIA----TMLEDVSMWIV 92 Query 687 TEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 EY G L+R + +P + ++ L YL + +H ++ NILL Sbjct 93 MEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEE 152 Query 746 GLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 G+ +KL D GV L R+ V W+APE + + + D W G Sbjct 153 GM-------VKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGI 205 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 T E+ G PL P + ++ +L P + CL P RPS Sbjct 206 TTYEL-LKGLPPLSKYDPMKVMTNLPKRKPPKLQGPFSDAAKDFVAGCLVKTPADRPSAY 264 Query 861 TIL 863 +L Sbjct 265 NLL 267 >sp|P43298|TMK1_ARATH Receptor protein kinase TMK1 OS=Arabidopsis thaliana OX=3702 GN=TMK1 PE=1 SV=1 Length=942 Score = 96.7 bits (239), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 78/222 (35%), Positives = 107/222 (48%), Gaps = 22/222 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 LG G FG V +DGT +AVK ++ + + +K EI +L + H H++ Sbjct 594 LGSGGFGVV---YKGELHDGT--KIAVKRMENGVIAGKGFAEFKSEIAVLTKVRHRHLVT 648 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYLH 1015 G C D EK LV EY+P G+L +L S + Q L A + G+ YLH Sbjct 649 LLGYCLDGNEK--LLVYEYMPQGTLSRHLFEWSEEGLKPLLWKQRLTLALDVARGVEYLH 706 Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APE 1071 Q +IHRDL N+LL +D K+ DFGL + PEG R G F Y APE Sbjct 707 GLAHQSFIHRDLKPSNILLGDDMRAKVADFGLVRLAPEGKGSIETRIAG---TFGYLAPE 763 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELI 1112 + DV+SFGV L EL+T S +S P + + L+ Sbjct 764 YAVTGRVTTKVDVYSFGVILMELITGRKSLDESQPEESIHLV 805 Score = 62.4 bits (150), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 65/247 (26%), Positives = 109/247 (44%), Gaps = 41/247 (17%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD--VWLRRERGHVPMAWK- 711 F +++++V H HL + G C+ G E ++V EY+ G L ++ E G P+ WK Sbjct 631 FKSEIAVLTKVRHRHLVTLLGYCLDGNEKLLVYEYMPQGTLSRHLFEWSEEGLKPLLWKQ 690 Query 712 -MVVAQQLASALSY---LENKNLVHGNVCGRNILLA---RLGLAEGTSPFIKLSDPGVGL 764 + +A +A + Y L +++ +H ++ NILL R +A+ ++L+ G G Sbjct 691 RLTLALDVARGVEYLHGLAHQSFIHRDLKPSNILLGDDMRAKVAD--FGLVRLAPEGKG- 747 Query 765 GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 S E R+ +LAPE G ++T +D + FG L+E+ G L P E Sbjct 748 ---SIETRIAGTFGYLAPEYAVTG--RVTTKVDVYSFGVILMEL-ITGRKSLDESQPEES 801 Query 824 EH---FYQRQHRLPEPSCPQ------------------LATLTSQCLTYEPTQRPSFRTI 862 H +++R + E S + +A L C EP QRP Sbjct 802 IHLVSWFKRMYINKEASFKKAIDTTIDLDEETLASVHTVAELAGHCCAREPYQRPDMGHA 861 Query 863 LRDLTRL 869 + L+ L Sbjct 862 VNILSSL 868 >sp|Q0IHQ8|STK10_XENTR Serine/threonine-protein kinase 10 OS=Xenopus tropicalis OX=8364 GN=stk10 PE=2 SV=1 Length=951 Score = 96.7 bits (239), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 85/287 (30%), Positives = 134/287 (47%), Gaps = 42/287 (15%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I +LG+G FGKV Y N TG + A K ++ + + EI+IL T H I Sbjct 39 IGELGDGAFGKV----YKAKNKETGILAAAKVIETK-NEEELEDYMVEIEILATCNHHFI 93 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQ 1017 +K G +G+ L +++E+ P G++ + GL + + +Q+ EG+ YLH+ Sbjct 94 VKLLGSYYWEGK--LWIMIEFCPGGAVDAIMLELDRGLKEPEIRTICRQMLEGLTYLHSM 151 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVFWYAP-----E 1071 IHRDL A NVLL D +K+ DFG+ AK V + + R+ +W AP E Sbjct 152 KMIHRDLKAGNVLLTLDGDIKLADFGVSAKNV----KTLQRRDSFIGTPYWMAPEVVMCE 207 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE----LIGIAQGQMTVLRLTEL 1127 +K+ + Y +D+WS G+TL E+ + PP L L+ IA+ + Sbjct 208 TMKDAPYDYKADIWSLGITLIEM-----AQIEPPHHELNPMRVLLKIAKSEPPT------ 256 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTV 1172 L P K E ++ +K + RP+ L+ P +K V Sbjct 257 ------LSSPSKWSPEFHNFLKTALDKNPETRPSAAQLLEHPFVKKV 297 Score = 39.3 bits (90), Expect = 0.29, Method: Compositional matrix adjust. Identities = 29/103 (28%), Positives = 45/103 (44%), Gaps = 14/103 (14%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV---GLGALSR 769 + +Q+ L+YL + ++H ++ N+LL G IKL+D GV + L R Sbjct 136 TICRQMLEGLTYLHSMKMIHRDLKAGNVLLTLDG-------DIKLADFGVSAKNVKTLQR 188 Query 770 EERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808 + P W+APE C D W G TL+E+ Sbjct 189 RDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIEMA 231 >sp|Q8R4K2|IRAK4_MOUSE Interleukin-1 receptor-associated kinase 4 OS=Mus musculus OX=10090 GN=Irak4 PE=1 SV=1 Length=459 Score = 94.7 bits (234), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 71/202 (35%), Positives = 100/202 (50%), Gaps = 19/202 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC---GPQHRSGWKQEIDILRTLYHEHI 959 +GEG FG V C + T +VAVK L A + + + QEI ++ T HE++ Sbjct 192 MGEGGFGVVYKGCVNNT------IVAVKKLGAMVEISTEELKQQFDQEIKVMATCQHENL 245 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLH 1015 ++ G D +L LV Y+P GSL D L + AQ G+ +LH Sbjct 246 VELLGFSSDS--DNLCLVYAYMPNGSLLDRLSCLDGTPPLSWHTRCKVAQGTANGIRFLH 303 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLK 1074 H+IHRD+ + N+LLD D KI DFGLA+A R G + + APE L+ Sbjct 304 ENHHIHRDIKSANILLDKDFTAKISDFGLARASARLAQTVMTSRIVGTTA--YMAPEALR 361 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + SD++SFGV L EL+T Sbjct 362 G-EITPKSDIYSFGVVLLELIT 382 Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 53/243 (22%), Positives = 100/243 (41%), Gaps = 33/243 (14%) Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 +++ S ++ F + +M+ H +L + G +V Y+ +G L L Sbjct 218 MVEISTEELKQQFDQEIKVMATCQHENLVELLGFSSDSDNLCLVYAYMPNGSLLDRLSCL 277 Query 703 RGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G P++W + VAQ A+ + +L + +H ++ NILL + A K+SD Sbjct 278 DGTPPLSWHTRCKVAQGTANGIRFLHENHHIHRDIKSANILLDKDFTA-------KISDF 330 Query 761 GVGLGA--LSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ + L++ RI ++APE L G ++ D + FG LLE+ A Sbjct 331 GLARASARLAQTVMTSRIVGTTAYMAPEALRG---EITPKSDIYSFGVVLLELITGLAAV 387 Query 815 LQSRSPS---------------EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859 ++R P +++ ++ S + + SQCL + +RP Sbjct 388 DENREPQLLLDIKEEIEDEEKTIEDYTDEKMSDADPASVEAMYSAASQCLHEKKNRRPDI 447 Query 860 RTI 862 + Sbjct 448 AKV 450 >sp|H2KZW3|M3K20_CAEEL Mitogen-activated protein kinase kinase kinase zak-1 OS=Caenorhabditis elegans OX=6239 GN=zak-1 PE=2 SV=1 Length=745 Score = 96.3 bits (238), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 80/277 (29%), Positives = 123/277 (44%), Gaps = 43/277 (16%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + DG+ +A+K + ++E +IL + H++II++ Sbjct 37 IGVGTFGAVFSGNW-TLPDGSQRTIALKKVFV---------LEKEAEILSKIRHKNIIQF 86 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQ---------LLLFAQQICEGMA 1012 G C+ G +V EY GSL D++ S A ++ +A QI G+ Sbjct 87 YGICKATGNDFF-IVTEYAEKGSLYDFIHSEESQSFASSSGGNSFDVVVKWASQIASGIQ 145 Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH IHRDL ++NV+LD + + KI DFG +K + H G + W + Sbjct 146 YLHYDAVDTIIHRDLKSKNVVLDKNLVCKICDFGTSKDLT--HSCTAPSWGGTAA--WMS 201 Query 1070 PE-CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE L+ A+DVWS+GV L+E+L S + P + E T + Sbjct 202 PEMILQSEGLTTATDVWSYGVVLWEIL----SKEVPYKDYSEF----------RIFTMIT 247 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + G L P CP + LM NCW+ R + Sbjct 248 QSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQI 284 >sp|Q8GX23|PERK5_ARATH Proline-rich receptor-like protein kinase PERK5 OS=Arabidopsis thaliana OX=3702 GN=PERK5 PE=2 SV=1 Length=670 Score = 95.9 bits (237), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 73/203 (36%), Positives = 101/203 (50%), Gaps = 22/203 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V +G+ VAVK+LK G R ++ E+DI+ ++H H++ Sbjct 318 LGQGGFGYVHKGVLP-----SGKEVAVKSLKLGSGQGERE-FQAEVDIISRVHHRHLVSL 371 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017 G C G++ LV E++P +L +L H G L + A G+AYLH Sbjct 372 VGYCISGGQR--LLVYEFIPNNTLEFHL--HGKGRPVLDWPTRVKIALGSARGLAYLHED 427 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECL 1073 IHRD+ A N+LLD K+ DFGLAK + + + R G F Y APE Sbjct 428 CHPRIIHRDIKAANILLDFSFETKVADFGLAKLSQDNYTHVSTRVMG---TFGYLAPEYA 484 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 K SDV+SFGV L EL+T Sbjct 485 SSGKLSDKSDVFSFGVMLLELIT 507 Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 50/173 (29%), Positives = 76/173 (44%), Gaps = 25/173 (14%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F ++S+V H HL + G C+ G + ++V E++ + L+ L +G + W V Sbjct 353 FQAEVDIISRVHHRHLVSLVGYCISGGQRLLVYEFIPNNTLEFHLHG-KGRPVLDWPTRV 411 Query 715 AQQLASA--LSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 L SA L+YL ++H ++ NILL S K++D GL LS+ Sbjct 412 KIALGSARGLAYLHEDCHPRIIHRDIKAANILLD-------FSFETKVAD--FGLAKLSQ 462 Query 770 EERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 + +LAPE G LS D + FG LLE+ G PL Sbjct 463 DNYTHVSTRVMGTFGYLAPEYASSG--KLSDKSDVFSFGVMLLEL-ITGRPPL 512 >sp|P53666|LIMK2_CHICK LIM domain kinase 2 OS=Gallus gallus OX=9031 GN=LIMK2 PE=2 SV=1 Length=642 Score = 95.9 bits (237), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 63/211 (30%), Positives = 105/211 (50%), Gaps = 25/211 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+ T+ TG+++ +K L C + + + E+ ++R+L H +++K+ Sbjct 337 LGKGFFGQA----IKVTHKATGKVMVMKEL-IRCDEETQKTFLTEVKVMRSLDHPNVLKF 391 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G +K L L+ EY+ G+L+D+L Q + FA+ I GMAYLH+ IH Sbjct 392 IGVL--YKDKKLNLLTEYIEGGTLKDFLRNADPFPWQQKVSFAKGIASGMAYLHSMCIIH 449 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE---------YYRVREDGDSPV------- 1065 RDL + N L+ D+ V + DFGL++ + E + R D Sbjct 450 RDLNSHNCLIKLDKTVVVADFGLSRLIVEERKKPTLEKPSAKKRTLRKSDRKKRYTVVGN 509 Query 1066 -FWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 +W APE L + D++SFG+ L E++ Sbjct 510 PYWMAPEMLNGQSYDETVDIFSFGIVLCEII 540 Score = 57.8 bits (138), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 62/250 (25%), Positives = 100/250 (40%), Gaps = 35/250 (14%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +V+K L + F +M + H ++ GV + + ++TEY+E G L + Sbjct 357 MVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDF 416 Query 699 LRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNIL-------------LA 743 LR P W K+ A+ +AS ++YL + ++H ++ N L L+ Sbjct 417 LRNAD---PFPWQQKVSFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLS 473 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAMDK 797 RL + E P L P L + +R +R W+APE L G S +D Sbjct 474 RLIVEERKKP--TLEKPSAKKRTLRKSDRKKRYTVVGNPYWMAPEMLNG--QSYDETVDI 529 Query 798 WGFGATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYE 852 + FG L EI A P + F+++ +P P L + C E Sbjct 530 FSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEK--FVPADCPPAFFPLAAICCRLE 587 Query 853 PTQRPSFRTI 862 P RP F + Sbjct 588 PESRPPFSKL 597 >sp|P53668|LIMK1_MOUSE LIM domain kinase 1 OS=Mus musculus OX=10090 GN=Limk1 PE=1 SV=1 Length=647 Score = 95.9 bits (237), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 79/296 (27%), Positives = 133/296 (45%), Gaps = 41/296 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+ T+ TGE++ +K L R+ K E+ ++R L H +++K+ Sbjct 345 LGKGCFGQA----IKVTHRETGEVMVMKELIRFDEETQRTFLK-EVKVMRCLEHPNVLKF 399 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYI 1020 G +K L + EY+ G+LR + +Q + FA+ I GMAYLH+ + I Sbjct 400 IGVL--YKDKRLNFITEYIKGGTLRGIIKNMDSQYPWSQRVSFAKDIASGMAYLHSMNII 457 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAV---------------PEGHEYYRVREDGDSPV 1065 HRDL + N L+ +R V + DFGLA+ + P+ + Y V + Sbjct 458 HRDLNSHNCLVRENRNVVVADFGLARLMIDEKNQSEDLRSLKKPDRKKRYTVVGNP---- 513 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 +W APE + + DV+SFG+ L E++ ++ + ++ L + Sbjct 514 YWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDF---------GLNVR 564 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 L+R P CP + + C + + RP+F L L+T+ G P Sbjct 565 GFLDRY----CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETLRMHLSGHLP 616 Score = 66.2 bits (160), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 60/251 (24%), Positives = 110/251 (44%), Gaps = 22/251 (9%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +V+K L + F + +M + H ++ GV + +TEY++ G L Sbjct 365 MVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGI 424 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNV----C----GRNILLARLGLAEG 750 ++ P + ++ A+ +AS ++YL + N++H ++ C RN+++A GLA Sbjct 425 IKNMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLAR- 483 Query 751 TSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAMDKWGFGATL 804 I + L +L + +R +R W+APE + G S +D + FG L Sbjct 484 --LMIDEKNQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMING--RSYDEKVDVFSFGIVL 539 Query 805 LEIC--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSC-PQLATLTSQCLTYEPTQRPSFRT 861 EI + + R+ + R P+C P +T +C +P +RPSF Sbjct 540 CEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVK 599 Query 862 ILRDLTRLQPH 872 + + L L+ H Sbjct 600 LEQWLETLRMH 610 >sp|A4K2M3|STK4_PAPAN Serine/threonine-protein kinase 4 OS=Papio anubis OX=9555 GN=STK4 PE=3 SV=1 Length=487 Score = 94.7 bits (234), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V Y + TG++VA+K + + Q +EI I++ H+ Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 144 RKIHRDIKAGNILLNTEGQAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 201 YNCVADIWSLGITAIEM 217 Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 55/228 (24%), Positives = 84/228 (37%), Gaps = 21/228 (9%) Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 P D+ E S+M Q H+ +G + + +V EY G + +R Sbjct 62 PVESDLQEIIKEI-SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKT 120 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763 + + Q L YL +H ++ NILL G A KL+D GV Sbjct 121 LTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGQA-------KLADFGVAGQ 173 Query 764 -LGALSREERVERIP-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +++ V P W+APE + G N ++ D W G T +E+ +G+ P P Sbjct 174 LTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHP 229 Query 821 SEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R PE QCL P QR + +L+ Sbjct 230 MRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQ 277 >sp|Q54R58|YTYK2_DICDI Probable tyrosine-protein kinase DDB_G0283397 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0283397 PE=3 SV=1 Length=918 Score = 95.9 bits (237), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 87/290 (30%), Positives = 127/290 (44%), Gaps = 37/290 (13%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK--ALKADCGPQHRSGWKQEIDILR 952 R L +++G+G FGKV + G+ VA+K L + +E+ I+ Sbjct 175 RELTVEKEIGQGFFGKVYKARW------RGKSVALKKITLIKFRDLTETEIFDKEVSIMS 228 Query 953 TLYHEHIIKYKGCCEDQG-EKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQIC 1008 L H + + G C G ++MEY+ GSLR L S + + L A+ I Sbjct 229 KLCHPTCVMFIGACSLDGPSNDRSIIMEYMEGGSLRRLLDEKSSYHLPPSLQLSIARDIA 288 Query 1009 EGMAYLHAQH----YIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDS 1063 EGM YLH +HRDL + N+LL++ V KI DFGL+K + G Sbjct 289 EGMNYLHTNFKEGPIVHRDLTSSNILLNSSYTVAKINDFGLSKEMKPGPTEMTA---AMG 345 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 + W APEC K + DV+SF + L+E++T D M LR Sbjct 346 SLAWMAPECFKAENYTEKVDVYSFAIILWEIVTCRD---------------PYNGMEPLR 390 Query 1124 LTELLERGE-RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 L L + RLP P V L+ CW S RP+F+ ++ IL + Sbjct 391 LAFLASVEDYRLPLNGFPPYWV-ELISKCWNITPSLRPSFKEILQILNQI 439 Score = 77.8 bits (190), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 78/312 (25%), Positives = 135/312 (43%), Gaps = 54/312 (17%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S L H + +E+T +GQG VY+ R R G+ + Sbjct 165 STLKKHEIPSRELTVEKEIGQGFFGKVYKARWR--------------------GKSVALK 204 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSH-THLAFVHGVCVRGPEN--IMVTEYVEHG 693 ++K D + +I F + S+MS++ H T + F+ + GP N ++ EY+E G Sbjct 205 KITLIKFRDLTETEI---FDKEVSIMSKLCHPTCVMFIGACSLDGPSNDRSIIMEYMEGG 261 Query 694 PLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKN----LVHGNVCGRNILLARLGLA 748 L L + H+P + ++ +A+ +A ++YL +VH ++ NILL Sbjct 262 SLRRLLDEKSSYHLPPSLQLSIARDIAEGMNYLHTNFKEGPIVHRDLTSSNILL------ 315 Query 749 EGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 + K++D G+ G + + W+APEC A + + +D + F L Sbjct 316 NSSYTVAKINDFGLSKEMKPGPTEMTAAMGSLAWMAPECFK--AENYTEKVDVYSFAIIL 373 Query 805 LEIC-----FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQRPS 858 EI ++G PL+ + E + RLP P L S+C P+ RPS Sbjct 374 WEIVTCRDPYNGMEPLRLAFLASVEDY-----RLPLNGFPPYWVELISKCWNITPSLRPS 428 Query 859 FRTILRDLTRLQ 870 F+ IL+ L +++ Sbjct 429 FKEILQILNQIE 440 >sp|Q9LRY1|PBL25_ARATH Probable serine/threonine-protein kinase PBL25 OS=Arabidopsis thaliana OX=3702 GN=PBL25 PE=2 SV=1 Length=381 Score = 93.2 bits (230), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 96/319 (30%), Positives = 151/319 (47%), Gaps = 37/319 (12%) Query 875 ADVLTVNPDSPASD--PTVFHKRYL----KKIRD---LGEGHFGKVSLYCYDPTNDGTGE 925 +V+ N + P+++ +F R L K R +GEG FG+V Y + + Sbjct 34 GEVVAKNANGPSNNMGARIFTFRELATATKNFRQECLIGEGGFGRV----YKGKLENPAQ 89 Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 +VAVK L + G Q + + E+ +L L+H +++ G C D G++ L LV EY+PLGS Sbjct 90 VVAVKQLDRN-GLQGQREFLVEVLMLSLLHHRNLVNLIGYCAD-GDQRL-LVYEYMPLGS 146 Query 986 LRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLV 1037 L D+L G L + A +G+ YLH + I+RDL + N+LLD + + Sbjct 147 LEDHLLDLEPGQKPLDWNTRIKIALGAAKGIEYLHDEADPPVIYRDLKSSNILLDPEYVA 206 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 K+ DFGLAK P G + V + APE + SDV+SFGV L EL++ Sbjct 207 KLSDFGLAKLGPVGDTLH-VSSRVMGTYGYCAPEYQRTGYLTNKSDVYSFGVVLLELISG 265 Query 1098 ---CDSSQSPPTKFLELIG----IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 D+ + P+ L+ I + +L + L RG+ P+K + + Sbjct 266 RRVIDTMR--PSHEQNLVTWALPIFRDPTRYWQLADPLLRGD---YPEKSLNQAIAVAAM 320 Query 1151 CWETEASFRPTFENLIPIL 1169 C E + RP ++I L Sbjct 321 CLHEEPTVRPLMSDVITAL 339 Score = 55.8 bits (133), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 81/346 (23%), Positives = 136/346 (39%), Gaps = 63/346 (18%) Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEG 612 P T+ ++ + A + +F + K Q +G+G VY+G+L Sbjct 29 PKRTTGEVVAKNANGPSNNMGARIFTFRELATATKNFRQECLIGEGGFGRVYKGKL---- 84 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672 E+P V +K LD + F ++S + H +L Sbjct 85 -----------ENP---------AQVVAVKQLDRNGLQGQREFLVEVLMLSLLHHRNLVN 124 Query 673 VHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN 729 + G C G + ++V EY+ G L D L E G P+ W ++ +A A + YL ++ Sbjct 125 LIGYCADGDQRLLVYEYMPLGSLEDHLLDLEPGQKPLDWNTRIKIALGAAKGIEYLHDEA 184 Query 730 ---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERV-ERIPWLAPECL 784 +++ ++ NILL +A KLSD G+ LG + V R+ C Sbjct 185 DPPVIYRDLKSSNILLDPEYVA-------KLSDFGLAKLGPVGDTLHVSSRVMGTYGYCA 237 Query 785 PGGANS--LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH--------------FYQ 828 P + L+ D + FG LLE+ G + + PS +++ ++Q Sbjct 238 PEYQRTGYLTNKSDVYSFGVVLLEL-ISGRRVIDTMRPSHEQNLVTWALPIFRDPTRYWQ 296 Query 829 RQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 L PE S Q + + CL EPT RP ++ L+ L Sbjct 297 LADPLLRGDYPEKSLNQAIAVAAMCLHEEPTVRPLMSDVITALSFL 342 >sp|G4NEB8|MST7_PYRO7 Mitogen-activated protein kinase kinae MST7 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507 GN=MST7 PE=1 SV=1 Length=415 Score = 93.6 bits (231), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 77/281 (27%), Positives = 133/281 (47%), Gaps = 34/281 (12%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ I+DLG G+ G VS + PTN ++A K + + + R +E+ I+ + Sbjct 61 LEVIKDLGSGNGGTVSKVRHIPTN----TVMARKVIHVEAKREMRKRIVRELQIMHSCNS 116 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYL 1014 E+I+ + G ++ + + MEY +GSL D + R I + L A+ G+ YL Sbjct 117 EYIVTFYGAFLNENNDVI-MCMEYADVGSL-DRVSRVFGPIRVDVLGKIAEATLGGLTYL 174 Query 1015 HAQHYI-HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +A+H+I HRD+ N+L+++ +K+ DFG++ G + + + APE + Sbjct 175 YAKHHIMHRDIKPSNILVNSRGSIKLCDFGVS-----GELINSIADTFVGTSTYMAPERI 229 Query 1074 KEYKFYYASDVWSFGVTLYELLT---------HCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 + K+ SDVWSFG+++ EL ++S P L+L+ Q V Sbjct 230 QGEKYTVKSDVWSFGLSIMELAIGKFPFAASEQLSDAESAPAGILDLL-----QQIV--- 281 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 E +LP+ D P + +++ C RPT E L Sbjct 282 ---HEPAPKLPKSDAFPQILEDMIQKCLYKNPDDRPTPEEL 319 >sp|A4K2W5|STK4_AOTNA Serine/threonine-protein kinase 4 OS=Aotus nancymaae OX=37293 GN=STK4 PE=3 SV=1 Length=487 Score = 94.4 bits (233), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V Y + TG++VA+K + + Q +EI I++ H+ Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSHHV 85 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 201 YNCVADIWSLGITAIEM 217 Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q H+ +G + + +V EY G + +R + + Q Sbjct 75 SIMQQCDSHHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL +H ++ NILL G A KL+D GV +++ V Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187 Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830 P W+APE + G N ++ D W G T +E+ +G+ P P Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R PE QCL P QR + +L+ Sbjct 244 FRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQ 277 >sp|Q86I06|NEK3_DICDI Probable serine/threonine-protein kinase nek3 OS=Dictyostelium discoideum OX=44689 GN=nek3 PE=3 SV=1 Length=1123 Score = 96.3 bits (238), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 71/285 (25%), Positives = 133/285 (47%), Gaps = 50/285 (18%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEH 958 I+ +G+G FG+ L G ++ +K + + P+ RS E+++L L HE+ Sbjct 7 IKTIGKGSFGRAILV----KRKSDGLLLVLKEINVMEMQPKERSDAMNEVNLLSMLDHEN 62 Query 959 IIKY------KGCCEDQGEKSLQLVMEYVPLGSL-----RDYLPRHSIGLAQLLLFAQQI 1007 II Y GC L ++MEY G + + L + ++L + QI Sbjct 63 IIGYYDSFILNGC--------LYIIMEYANAGDINLEIKKRTLQNKTFSEFEILSWFSQI 114 Query 1008 CEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 C+ + Y+ +++ +HRDL +N+ L + D +K+GDFG+AK + E +P Sbjct 115 CKALQYISSRNILHRDLKTQNIFLSIVNGDYFIKLGDFGIAKIL--NSETSLASTVLGTP 172 Query 1065 VFWYAPECLKEYKFY-YASDVWSFGVTLYELLT--HCDSSQSPPTKFLELIGIAQGQMTV 1121 ++ +PE ++ K Y + SD+WS G LYEL T H ++ + P L+++ Sbjct 173 -YYLSPELIQNEKGYDHKSDIWSLGCVLYELTTLKHAFNAANLPALVLKIL--------- 222 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 +G P P ++ +L+ + + + RP+ +++ Sbjct 223 --------KGTYPPIPSHYSNDLRNLISSMLQIDPKNRPSVNDIL 259 Score = 37.7 bits (86), Expect = 0.85, Method: Compositional matrix adjust. Identities = 47/219 (21%), Positives = 89/219 (41%), Gaps = 25/219 (11%) Query 659 ASLMSQVSHTHL-----AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 +L+S + H ++ +F+ C+ ++ EY G +++ +++ + Sbjct 52 VNLLSMLDHENIIGYYDSFILNGCLY-----IIMEYANAGDINLEIKKRTLQNKTFSEFE 106 Query 714 VAQ---QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + Q+ AL Y+ ++N++H ++ +NI L+ + G FIKL D G+ L+ E Sbjct 107 ILSWFSQICKALQYISSRNILHRDLKTQNIFLS---IVNGDY-FIKLGDFGIA-KILNSE 161 Query 771 ERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 + +L+PE + D W G L E+ A + P+ Sbjct 162 TSLASTVLGTPYYLSPELI-QNEKGYDHKSDIWSLGCVLYELTTLKHAFNAANLPALVLK 220 Query 826 FYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 + + +P L L S L +P RPS IL Sbjct 221 ILKGTYPPIPSHYSNDLRNLISSMLQIDPKNRPSVNDIL 259 >sp|A0A2R6XIK6|PRAF_MARPO RAF-like serine/threonine-protein kinase PRAF OS=Marchantia polymorpha OX=3197 GN=PRAF PE=1 SV=1 Length=1680 Score = 96.3 bits (238), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 88/297 (30%), Positives = 135/297 (45%), Gaps = 41/297 (14%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-----GPQHR---SGWKQEI 948 L+++R+LG G FG V + T+ VA+K +KA C Q R W++ Sbjct 1389 LEELRELGSGTFGTVYHGKWRGTD------VAIKRIKASCFAGRPSEQERLIEDFWREAC 1442 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQ 1006 + L L+H +++ + G D +L V EY+ GSL+ L + +I + LL A Sbjct 1443 N-LGHLHHPNVVAFYGVVADGPGGTLATVTEYMVNGSLKQVLQKKDRTIDRRKRLLIAMD 1501 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLD----NDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 GM YLH ++ +H DL N+L++ + + K+GD GL+K + VR G Sbjct 1502 AAFGMEYLHGKNIVHFDLKCENLLVNMRDPHRPICKVGDLGLSKVKHQTMVSGGVR--GT 1559 Query 1063 SPVFWYAPECLKEYKFYYAS--DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 P W APE L DV+SFG+ ++ELLT + P K G G + Sbjct 1560 LP--WMAPELLNGNSSLVTEKVDVFSFGIVMWELLT----GEEPYDKM--HYGAIIGGIV 1611 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 L L+ P C LM+ CW E + RP+F ++ L+T+ Q Sbjct 1612 NNTLRPLI--------PSWCDPAWRSLMERCWANEPAVRPSFSDIAKELRTMAAALQ 1660 Score = 75.1 bits (183), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 74/317 (23%), Positives = 131/317 (41%), Gaps = 54/317 (17%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG-QELRV 639 + ++ +L LG GT VY G+ R G D + ++ Sbjct 1381 LQTIKNADLEELRELGSGTFGTVYHGKWR--------------------GTDVAIKRIKA 1420 Query 640 VLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEYVEHGPLD 696 PS + + F+ A + + H ++ +GV GP + VTEY+ +G L Sbjct 1421 SCFAGRPSEQERLIEDFWREACNLGHLHHPNVVAFYGVVADGPGGTLATVTEYMVNGSLK 1480 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 L+++ + ++++A A + YL KN+VH ++ N+L + + + P K Sbjct 1481 QVLQKKDRTIDRRKRLLIAMDAAFGMEYLHGKNIVHFDLKCENLL---VNMRDPHRPICK 1537 Query 757 LSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 + D +GL + + V +PW+APE L G ++ ++ +D + FG + E+ Sbjct 1538 VGD--LGLSKVKHQTMVSGGVRGTLPWMAPELLNGNSSLVTEKVDVFSFGIVMWEL---- 1591 Query 812 EAPLQSRSPSEKEHF---------YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 L P +K H+ + +P P +L +C EP RPSF I Sbjct 1592 ---LTGEEPYDKMHYGAIIGGIVNNTLRPLIPSWCDPAWRSLMERCWANEPAVRPSFSDI 1648 Query 863 LRDL----TRLQPHNLA 875 ++L LQP A Sbjct 1649 AKELRTMAAALQPKTQA 1665 >sp|Q9H2K8|TAOK3_HUMAN Serine/threonine-protein kinase TAO3 OS=Homo sapiens OX=9606 GN=TAOK3 PE=1 SV=2 Length=898 Score = 95.9 bits (237), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 72/203 (35%), Positives = 102/203 (50%), Gaps = 23/203 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956 + ++G G FG V Y TN T E+VA+K + + G Q W+ +E+ LR L H Sbjct 27 LHEIGHGSFGAV----YFATNAHTSEVVAIKKM-SYSGKQTHEKWQDILKEVKFLRQLKH 81 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014 + I+YKGC E + LVMEY LGS D L H L ++ + A G+AYL Sbjct 82 PNTIEYKGCY--LKEHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALHGLAYL 138 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071 H+ IHRD+ A N+LL VK+ DFG A + + +P +W APE Sbjct 139 HSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFV------GTP-YWMAPEVIL 191 Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094 + E ++ D+WS G+T EL Sbjct 192 AMDEGQYDGKVDIWSLGITCIEL 214 >sp|Q54H46|DRKA_DICDI Probable serine/threonine-protein kinase drkA OS=Dictyostelium discoideum OX=44689 GN=drkA PE=3 SV=1 Length=642 Score = 95.1 bits (235), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 80/278 (29%), Positives = 131/278 (47%), Gaps = 38/278 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGT--GEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHI 959 +G+G++G+V L GT G VAVK L A + + +EI++++ L H ++ Sbjct 380 IGKGNYGEVYL--------GTWRGSQVAVKKLPAHNINENILKEFHREINLMKNLRHPNV 431 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI--CEGMAYLHAQ 1017 I++ G C + + + EY+P GSL L ++ L LL I +G+ YLH Sbjct 432 IQFLGSCLIPPD--ICICTEYMPRGSLYSILHDQALQLQWSLLIKMMIDAAKGVIYLHNS 489 Query 1018 H--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRDL + N+L+D + VK+ DFGL+ +G +P W +PE L+ Sbjct 490 TPVILHRDLKSHNLLVDENWKVKVADFGLSTIEQQG----ATMTACGTPC-WTSPEVLRS 544 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 ++ +DV+SFG+ L+E T D PP + + +G G R Sbjct 545 QRYTEKADVYSFGIILWECATRQDPYFGIPPFQVIFAVG---------------REGMRP 589 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P P P + L+ +C S RPT E + L+++ Sbjct 590 PVPQNGPPKYIQLLIDCLNENPSHRPTMEQCLERLESI 627 Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust. Identities = 67/315 (21%), Positives = 131/315 (42%), Gaps = 43/315 (14%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVE-GSGDPEEGKMDDEDPLVPGRDRGQELRV 639 +++ D+ + TQ+ G ++++ ++ V G G+ E + G RG + V Sbjct 352 YYKPDKNDYTQIK---DGKDIDIHQIKIGVRIGKGNYGEVYL--------GTWRGSQ--V 398 Query 640 VLKVLDPSHH---DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +K L P+H+ +I F+ +LM + H ++ G C+ P+ + TEY+ G L Sbjct 399 AVKKL-PAHNINENILKEFHREINLMKNLRHPNVIQFLGSCLIPPDICICTEYMPRGSLY 457 Query 697 VWLRRERGHVPMAWKMVVAQQL--ASALSYLENKN--LVHGNVCGRNILLARLGLAEGTS 752 L + + + W +++ + A + YL N ++H ++ N+L+ + Sbjct 458 SILHDQA--LQLQWSLLIKMMIDAAKGVIYLHNSTPVILHRDLKSHNLLVDE-------N 508 Query 753 PFIKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 +K++D GL + ++ W +PE L + + D + FG L E C Sbjct 509 WKVKVAD--FGLSTIEQQGATMTACGTPCWTSPEVLR--SQRYTEKADVYSFGIILWE-C 563 Query 809 FDGEAPLQSRSPSEKEHFYQRQHR---LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + P P + R+ +P+ P+ L CL P+ RP+ L Sbjct 564 ATRQDPYFGIPPFQVIFAVGREGMRPPVPQNGPPKYIQLLIDCLNENPSHRPTMEQCLER 623 Query 866 LTRLQPHNLADVLTV 880 L + +D+ V Sbjct 624 LESIDSSGYSDLQYV 638 >sp|Q9FE20|PBS1_ARATH Serine/threonine-protein kinase PBS1 OS=Arabidopsis thaliana OX=3702 GN=PBS1 PE=1 SV=1 Length=456 Score = 94.0 bits (232), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 73/205 (36%), Positives = 105/205 (51%), Gaps = 22/205 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG+V Y D TG++VAVK L + G Q + E+ +L L+H +++ Sbjct 92 LGEGGFGRV----YKGRLDSTGQVVAVKQLDRN-GLQGNREFLVEVLMLSLLHHPNLVNL 146 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 G C D G++ L LV E++PLGSL D+L + ++ + A +G+ +LH + Sbjct 147 IGYCAD-GDQRL-LVYEFMPLGSLEDHLHDLPPDKEALDWNMRMKIAAGAAKGLEFLHDK 204 Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG---HEYYRVREDGDSPVFWYAPE 1071 I+RD + N+LLD K+ DFGLAK P G H RV + APE Sbjct 205 ANPPVIYRDFKSSNILLDEGFHPKLSDFGLAKLGPTGDKSHVSTRVM----GTYGYCAPE 260 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 + SDV+SFGV EL+T Sbjct 261 YAMTGQLTVKSDVYSFGVVFLELIT 285 >sp|Q1PDV6|PBL27_ARATH Serine/threonine-protein kinase PBL27 OS=Arabidopsis thaliana OX=3702 GN=PBL27 PE=1 SV=1 Length=513 Score = 94.4 bits (233), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 74/213 (35%), Positives = 112/213 (53%), Gaps = 19/213 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG+V Y + TG++VAVK L + G Q + E+ +L L+H +++ Sbjct 89 LGEGGFGRV----YKGRLETTGQIVAVKQLDRN-GLQGNREFLVEVLMLSLLHHPNLVNL 143 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 G C D G++ L LV EY+PLGSL D+L + + + + A +G+ YLH + Sbjct 144 IGYCAD-GDQRL-LVYEYMPLGSLEDHLHDLPPDKEPLDWSTRMTIAAGAAKGLEYLHDK 201 Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 I+RDL + N+LL + K+ DFGLAK P G + + V + APE Sbjct 202 ANPPVIYRDLKSSNILLGDGYHPKLSDFGLAKLGPVGDKTH-VSTRVMGTYGYCAPEYAM 260 Query 1075 EYKFYYASDVWSFGVTLYELLT---HCDSSQSP 1104 + SDV+SFGV EL+T D++++P Sbjct 261 TGQLTLKSDVYSFGVVFLELITGRKAIDNARAP 293 Score = 54.3 bits (129), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 75/317 (24%), Positives = 124/317 (39%), Gaps = 59/317 (19%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LG+G VY+GRL G V +K LD + Sbjct 89 LGEGGFGRVYKGRLETTGQ------------------------IVAVKQLDRNGLQGNRE 124 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--K 711 F ++S + H +L + G C G + ++V EY+ G L+ L P+ W + Sbjct 125 FLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEYMPLGSLEDHLHDLPPDKEPLDWSTR 184 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSRE 770 M +A A L YL +K + V R++ + + L +G P KLSD G+ LG + + Sbjct 185 MTIAAGAAKGLEYLHDK--ANPPVIYRDLKSSNILLGDGYHP--KLSDFGLAKLGPVGDK 240 Query 771 ERVE-RIPWLAPECLPGGA--NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE----- 822 V R+ C P A L+ D + FG LE+ +A +R+P E Sbjct 241 THVSTRVMGTYGYCAPEYAMTGQLTLKSDVYSFGVVFLELITGRKAIDNARAPGEHNLVA 300 Query 823 -KEHFYQRQHRLPEPSCPQLA------------TLTSQCLTYEPTQRPSFRTILRDLTRL 869 ++ + + P+ + P L + + CL + RP ++ LT L Sbjct 301 WARPLFKDRRKFPKMADPSLQGRYPMRGLYQALAVAAMCLQEQAATRPLIGDVVTALTYL 360 Query 870 QPHNLADVLTVNPDSPA 886 T +P++P+ Sbjct 361 ASQ------TFDPNAPS 371 >sp|Q9JI11|STK4_MOUSE Serine/threonine-protein kinase 4 OS=Mus musculus OX=10090 GN=Stk4 PE=1 SV=1 Length=487 Score = 94.4 bits (233), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V Y + TG++VA+K + + Q +EI I++ H+ Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 201 YNCVADIWSLGITAIEM 217 Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q H+ +G + + +V EY G + +R + + Q Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL +H ++ NILL G A KL+D GV +++ V Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187 Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830 P W+APE + G N ++ D W G T +E+ +G+ P P Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R PE QCL P QR + +L+ Sbjct 244 FRKPELWSDNFMDFVKQCLVKSPEQRATATQLLQ 277 >sp|Q9P0L2|MARK1_HUMAN Serine/threonine-protein kinase MARK1 OS=Homo sapiens OX=9606 GN=MARK1 PE=1 SV=2 Length=795 Score = 95.5 bits (236), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 69/199 (35%), Positives = 100/199 (50%), Gaps = 13/199 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G+G+F KV L + T G VAVK + K P +E+ I++ L H +I Sbjct 64 KTIGKGNFAKVKLARHVLT----GREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQH 1018 +K E EK+L LVMEY G + DYL H + + +QI + Y H ++ Sbjct 120 VKLFEVIET--EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 177 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRDL A N+LLD D +KI DFG + G++ G P + APE + K+ Sbjct 178 IVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTF--CGSPP--YAAPELFQGKKY 233 Query 1079 YYAS-DVWSFGVTLYELLT 1096 DVWS GV LY L++ Sbjct 234 DGPEVDVWSLGVILYTLVS 252 Score = 34.7 bits (78), Expect = 7.2, Method: Compositional matrix adjust. Identities = 51/236 (22%), Positives = 93/236 (39%), Gaps = 22/236 (9%) Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K++D + + + +M ++H ++ + V +V EY G + Sbjct 86 VAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVF 145 Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 +L H M K A+ Q+ SA+ Y K +VH ++ N+LL Sbjct 146 DYLV---AHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLL-------DGDMN 195 Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 IK++D G + +++ P+ APE G +D W G L + Sbjct 196 IKIADFGFS-NEFTVGNKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLV-S 252 Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 G P ++ E +E + ++R+P L + L P +R S I++D Sbjct 253 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKD 308 >sp|P38692|KIC1_YEAST Serine/threonine-protein kinase KIC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=KIC1 PE=1 SV=1 Length=1080 Score = 95.9 bits (237), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 66/209 (32%), Positives = 101/209 (48%), Gaps = 15/209 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 K+ +G G FG V Y N TG + A+K L D ++EI L +L Sbjct 23 FKRTEVIGRGKFGVV----YKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQ 78 Query 957 -EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH 1015 +I +Y G + SL ++ME+ GSLR L I + + +++ + +H Sbjct 79 ISNITRYYGSY--LKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIH 136 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + IHRD+ A NVL+ N+ VK+ DFG+A V R + +P +W APE + E Sbjct 137 KDNVIHRDIKAANVLITNEGNVKLCDFGVAAQV--NQTSLRRQTMAGTP-YWMAPEVIME 193 Query 1076 YKFYYAS-DVWSFGVTLYELLT----HCD 1099 +Y D+WS G+T YE+ T +CD Sbjct 194 GVYYDTKVDIWSLGITTYEIATGNPPYCD 222 Score = 41.2 bits (95), Expect = 0.065, Method: Compositional matrix adjust. Identities = 34/128 (27%), Positives = 55/128 (43%), Gaps = 14/128 (11%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 ++ E+ G L LR G + + V+ ++L AL + N++H ++ N+L+ Sbjct 97 IIMEHCAGGSLRSLLRP--GKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITN 154 Query 745 LGLAEGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800 G +KL D GV +L R+ W+APE + G T +D W Sbjct 155 EG-------NVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGV-YYDTKVDIWSL 206 Query 801 GATLLEIC 808 G T EI Sbjct 207 GITTYEIA 214 >sp|A8X775|DLK1_CAEBR Mitogen-activated protein kinase kinase kinase dlk-1 OS=Caenorhabditis briggsae OX=6238 GN=dlk-1 PE=3 SV=1 Length=857 Score = 95.5 bits (236), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 71/227 (31%), Positives = 110/227 (48%), Gaps = 34/227 (15%) Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQ 1005 EI LR L H++II++ G C +VMEY P G L L + ++ Q+ + + Sbjct 98 EIKHLRHLRHKNIIEFLGVCSKS--PCYCIVMEYCPKGQLCTVLRQKNLITRQMFSDWVK 155 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS-- 1063 +I +GM YLH IHRDL + N+L+ + +KI DFG + +++ DS Sbjct 156 EIADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTS----------HLQKKNDSTM 205 Query 1064 -----PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 V W APE +K+ DV+SFGV L+E+LT ++P IAQ Sbjct 206 MSFCGTVSWMAPEMIKKEPCNEKVDVYSFGVVLWEMLTR----ETP------YANIAQMA 255 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + T +L LP P++ P + L+K C + RP+F ++ Sbjct 256 IIFGVGTNILN----LPMPEEAPRGLVLLIKQCLSQKGRNRPSFSHI 298 Score = 40.4 bits (93), Expect = 0.13, Method: Compositional matrix adjust. Identities = 50/214 (23%), Positives = 88/214 (41%), Gaps = 22/214 (10%) Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726 H ++ GVC + P +V EY G L LR++ + V +++A + YL Sbjct 107 HKNIIEFLGVCSKSPCYCIVMEYCPKGQLCTVLRQKNLITRQMFSDWV-KEIADGMHYLH 165 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER----IPWLAPE 782 ++H ++ NIL++ AE + IK+ D G + + + W+APE Sbjct 166 QNKVIHRDLKSPNILIS----AEDS---IKICDFGTSHLQKKNDSTMMSFCGTVSWMAPE 218 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-----LPEPS 837 + + +D + FG L E+ E P + ++ + +PE + Sbjct 219 MIK--KEPCNEKVDVYSFGVVLWEM-LTRETPYA--NIAQMAIIFGVGTNILNLPMPEEA 273 Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 L L QCL+ + RPSF I + +P Sbjct 274 PRGLVLLIKQCLSQKGRNRPSFSHIRQHWEIFKP 307 >sp|Q13043|STK4_HUMAN Serine/threonine-protein kinase 4 OS=Homo sapiens OX=9606 GN=STK4 PE=1 SV=2 Length=487 Score = 94.4 bits (233), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V Y + TG++VA+K + + Q +EI I++ H+ Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 201 YNCVADIWSLGITAIEM 217 Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q H+ +G + + +V EY G + +R + + Q Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL +H ++ NILL G A KL+D GV +++ V Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187 Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830 P W+APE + G N ++ D W G T +E+ +G+ P P Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R PE QCL P QR + +L+ Sbjct 244 FRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQ 277 >sp|Q96S53|TESK2_HUMAN Dual specificity testis-specific protein kinase 2 OS=Homo sapiens OX=9606 GN=TESK2 PE=1 SV=1 Length=571 Score = 94.7 bits (234), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 76/284 (27%), Positives = 127/284 (45%), Gaps = 39/284 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G F +V + + +G+ V ALK + +R+ +E+ ++ L H +I+++ Sbjct 64 IGSGFFSEV----FKVRHRASGQ---VMALKMNTLSSNRANMLKEVQLMNRLSHPNILRF 116 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G C QG+ L + EY+ G+L L + + + A I G++YLH + H Sbjct 117 MGVCVHQGQ--LHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFH 174 Query 1022 RDLAARNVLLDNDR---LVKIGDFGLAKAVPE---GHEYYRVREDGDSPVFWYAPECLKE 1075 RDL ++N L+ D + DFGLA+ +P+ G E V SP FW APE L++ Sbjct 175 RDLTSKNCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVV---GSP-FWMAPEVLRD 230 Query 1076 YKFYYASDVWSFGVTLYELLT--HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + +DV+S+G+ L E++ D P T+ L A M Sbjct 231 EPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMV------------- 277 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 CP + L NC + RP+F + L+ + + Q Sbjct 278 ----GDCPPDFLQLTFNCCNMDPKLRPSFVEIGKTLEEILSRLQ 317 Score = 63.2 bits (152), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 68/258 (26%), Positives = 111/258 (43%), Gaps = 36/258 (14%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 R GQ + + + L + ++ + LM+++SH ++ GVCV + +TEY+ Sbjct 78 RASGQVMALKMNTLSSNRANM----LKEVQLMNRLSHPNILRFMGVCVHQGQLHALTEYI 133 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR------ 744 G L+ L H+P ++ +A +A LSYL K + H ++ +N L+ R Sbjct 134 NSGNLEQLLDSNL-HLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYS 192 Query 745 -----LGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 GLAE K+ D +G L+ V W+APE L + D + Sbjct 193 AVVADFGLAE------KIPDVSMGSEKLA---VVGSPFWMAPEVL--RDEPYNEKADVFS 241 Query 800 FGATLLEIC--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSC-PQLATLTSQCLTYEPTQR 856 +G L EI + R+ + + QH + + C P LT C +P R Sbjct 242 YGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGD--CPPDFLQLTFNCCNMDPKLR 299 Query 857 PSF----RTILRDLTRLQ 870 PSF +T+ L+RLQ Sbjct 300 PSFVEIGKTLEEILSRLQ 317 >sp|A4K2T0|STK4_MACMU Serine/threonine-protein kinase 4 OS=Macaca mulatta OX=9544 GN=STK4 PE=3 SV=1 Length=487 Score = 94.4 bits (233), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V Y + TG++VA+K + + Q +EI I++ H+ Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 201 YNCVADIWSLGITAIEM 217 Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q H+ +G + + +V EY G + +R + + Q Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL +H ++ NILL G A KL+D GV +++ V Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187 Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830 P W+APE + G N ++ D W G T +E+ +G+ P P Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R PE QCL P QR + +L+ Sbjct 244 FRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQ 277 >sp|A4K2Y1|STK4_CHLAE Serine/threonine-protein kinase 4 OS=Chlorocebus aethiops OX=9534 GN=STK4 PE=3 SV=1 Length=487 Score = 94.0 bits (232), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V Y + TG++VA+K + + Q +EI I++ H+ Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 201 YNCVADIWSLGITAIEM 217 Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q H+ +G + + +V EY G + +R + + Q Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL +H ++ NILL G A KL+D GV +++ V Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187 Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830 P W+APE + G N ++ D W G T +E+ +G+ P P Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R PE QCL P QR + +L+ Sbjct 244 FRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQ 277 >sp|P53669|LIMK1_RAT LIM domain kinase 1 OS=Rattus norvegicus OX=10116 GN=Limk1 PE=1 SV=1 Length=647 Score = 95.1 bits (235), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 79/296 (27%), Positives = 133/296 (45%), Gaps = 41/296 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+ T+ TGE++ +K L R+ K E+ ++R L H +++K+ Sbjct 345 LGKGCFGQA----IKVTHRETGEVMVMKELIRFDEETQRTFLK-EVKVMRCLEHPNVLKF 399 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYI 1020 G +K L + EY+ G+LR + +Q + FA+ I GMAYLH+ + I Sbjct 400 IGVLYK--DKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNII 457 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAV---------------PEGHEYYRVREDGDSPV 1065 HRDL + N L+ +R V + DFGLA+ + P+ + Y V + Sbjct 458 HRDLNSHNCLVRENRNVVVADFGLARLMIDEKGQSEDLRSLKKPDRKKRYTVVGNP---- 513 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 +W APE + + DV+SFG+ L E++ ++ + ++ L + Sbjct 514 YWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDF---------GLNVR 564 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 L+R P CP + + C + + RP+F L L+T+ G P Sbjct 565 GFLDRY----CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETLRMHLAGHLP 616 Score = 65.5 bits (158), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 64/261 (25%), Positives = 114/261 (44%), Gaps = 23/261 (9%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +V+K L + F + +M + H ++ GV + +TEY++ G L Sbjct 365 MVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGI 424 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNV----C----GRNILLARLGLAEG 750 ++ P + ++ A+ +AS ++YL + N++H ++ C RN+++A GLA Sbjct 425 IKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLAR- 483 Query 751 TSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAMDKWGFGATL 804 I L +L + +R +R W+APE + G S +D + FG L Sbjct 484 --LMIDEKGQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMING--RSYDEKVDVFSFGIVL 539 Query 805 LEIC--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSC-PQLATLTSQCLTYEPTQRPSFRT 861 EI + + R+ + R P+C P +T +C +P +RPSF Sbjct 540 CEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVK 599 Query 862 ILRDLTRLQPHNLADVLTVNP 882 + + L L+ H LA L + P Sbjct 600 LEQWLETLRMH-LAGHLPLGP 619 >sp|Q80YE4|LMTK1_MOUSE Serine/threonine-protein kinase LMTK1 OS=Mus musculus OX=10090 GN=Aatk PE=1 SV=1 Length=1365 Score = 95.9 bits (237), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 74/220 (34%), Positives = 111/220 (50%), Gaps = 20/220 (9%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 T + L ++++G G FGKV + + + +G V VK LK Q + + +E Sbjct 119 TDLGRHSLLYLKEIGHGWFGKV--FLGEVHSGVSGTQVVVKELKVSASVQEQMQFLEEAQ 176 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQI 1007 R L H ++++ C + LVME+ PLG L+ YL R + +A L Q++ Sbjct 177 PYRALQHSNLLQCLAQCAEV--TPYLLVMEFCPLGDLKGYLRSCRVTESMAPDPLTLQRM 234 Query 1008 -CE---GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD- 1062 CE G+ +LH +Y+H DLA RN LL D VK+GD+GL+ + E Y V D Sbjct 235 ACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLSHC--KYREDYLVTADQLW 292 Query 1063 SPVFWYAPECLKE-------YKFYYASDVWSFGVTLYELL 1095 P+ W APE + E +S+VWS GVT++EL Sbjct 293 VPLRWIAPELVDEVHGNLLVVDQTKSSNVWSLGVTIWELF 332 >sp|Q01389|BCK1_YEAST Serine/threonine-protein kinase BCK1/SLK1/SSP31 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=BCK1 PE=1 SV=1 Length=1478 Score = 95.9 bits (237), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 68/207 (33%), Positives = 106/207 (51%), Gaps = 27/207 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS----------GWKQEIDILR 952 +G+G FG V L C + T TGEM+AVK ++ P++ S + E+ L+ Sbjct 1181 IGKGSFGAVYL-CLNVT---TGEMMAVKQVEV---PKYSSQNEAILSTVEALRSEVSTLK 1233 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYV---PLGSLRDYLPRHSIGLAQLLLFAQQICE 1009 L H +I++Y G + L +EYV +GSL R L + L Q+ + Sbjct 1234 DLDHLNIVQYLGF--ENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHL--TTQVLK 1289 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 G+AYLH++ +HRD+ A N+LLD D + KI DFG+++ + + + G VFW A Sbjct 1290 GLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGT--VFWMA 1347 Query 1070 PECLKEYKFYYAS-DVWSFGVTLYELL 1095 PE + + Y A D+WS G + E+ Sbjct 1348 PEMVDTKQGYSAKVDIWSLGCIVLEMF 1374 Score = 43.1 bits (100), Expect = 0.018, Method: Compositional matrix adjust. Identities = 61/248 (25%), Positives = 103/248 (42%), Gaps = 31/248 (13%) Query 636 ELRVVLKVLDPSHHDIALAFYETA-SLMSQVSH----THLAFVHGVCVRGPENI--MVTE 688 E+ V +V P + A T +L S+VS HL V + NI + E Sbjct 1199 EMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLE 1258 Query 689 YVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 YV G + +R R P+ + Q+ L+YL +K ++H ++ N+LL + G+ Sbjct 1259 YVAGGSVGSLIRMYGRFDEPLIKHLTT--QVLKGLAYLHSKGILHRDMKADNLLLDQDGI 1316 Query 748 AEGTSPFIKLSDPGVGLGA---LSREERVER--IPWLAPECLPGGANSLSTAMDKWGFGA 802 K+SD G+ + S + R + W+APE + S +D W G Sbjct 1317 C-------KISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMV-DTKQGYSAKVDIWSLGC 1368 Query 803 TLLEICFDGEAP---LQSRSPSEKEHFYQRQHRLPEPSCPQLA----TLTSQCLTYEPTQ 855 +LE+ F G+ P L+ + K + +PE + P ++ C P + Sbjct 1369 IVLEM-FAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEK 1427 Query 856 RPSFRTIL 863 RP+ +L Sbjct 1428 RPTANELL 1435 >sp|P0DP15|SNF1_FUSVI Sucrose non-fermenting protein kinase 1 OS=Fusarium virguliforme OX=232082 GN=SNF1 PE=3 SV=1 Length=698 Score = 95.1 bits (235), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 76/204 (37%), Positives = 106/204 (52%), Gaps = 17/204 (8%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK--ALKADCGPQHRSGWKQEIDILRTLY 955 K +R LGEG FGKV L ++ GTG+ VA+K A K ++EI+ L+ L Sbjct 63 KVLRTLGEGSFGKVKLAIHN----GTGQQVALKIIARKKLISRDMAGRVEREIEYLQLLR 118 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYL 1014 H HIIK + E + +V+EY G L DY+ +H + A+ F QQ+ + Y Sbjct 119 HPHIIKLYTVIKTPNE--IIMVLEYAG-GELFDYIVQHGRMKEAEARRFFQQMLCAVEYC 175 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H +HRDL N+LLD + VKI DFGL+ + +G+ ++ SP + APE + Sbjct 176 HRHKIVHRDLKPENLLLDENLNVKIADFGLSNIMTDGN---FLKTSCGSPNY-AAPEVIG 231 Query 1075 EYKFYYAS--DVWSFGVTLYELLT 1096 K Y DVWS GV LY LL Sbjct 232 G-KLYAGPEVDVWSCGVILYVLLV 254 >sp|Q54IP4|SHKB_DICDI Dual specificity protein kinase shkB OS=Dictyostelium discoideum OX=44689 GN=shkB PE=3 SV=1 Length=653 Score = 95.1 bits (235), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 80/280 (29%), Positives = 133/280 (48%), Gaps = 34/280 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIK 961 LG G FG V G+ VA+K L ++ + +K+E+ ++ L + H++ Sbjct 180 LGSGAFGSVYKGIV------RGKEVAIKKLTQTVFEENTMNEFKKEVSLMAKLRNPHLLL 233 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHA 1016 + G C + L +V E +P GS+ L I + +L A+ GM +LHA Sbjct 234 FMGAC--TAPEDLSIVTELMPKGSVHSLLRAKEDTSDFITFKRAILIARDTVLGMTWLHA 291 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLKE 1075 + +H DL N+L+D + +VK+ DFGL+K + P+ + ++ SP++ APE L Sbjct 292 SNILHLDLKPANLLVDQNWVVKVADFGLSKYMKPDSKD--KLLGQAGSPLY-MAPEMLVN 348 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE-LLERGERL 1134 + DV+SF + L+ELLT Q P K + +L E ++ + R Sbjct 349 QPYDGKVDVFSFSILLWELLTK----QEPYNKLYS---------SYPQLVEGVVNKKNRP 395 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIP--ILKTV 1172 PD P + L+ CW+ S RP+F + IL+T+ Sbjct 396 IIPDYFPTRLKDLLARCWDHYPSRRPSFAEISKQRILETI 435 Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 82/387 (21%), Positives = 160/387 (41%), Gaps = 46/387 (12%) Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 +I+ G+ T +S S D++EI + + R + R GSG Sbjct 135 VILNGSLTEDSTSTISPDSTKNRDEEEIIRW----EIDRNEISYNREAKLGSGAF----- 185 Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 + G RG+E+ + + F + SLM+++ + HL G C P Sbjct 186 ---GSVYKGIVRGKEVAIKKLTQTVFEENTMNEFKKEVSLMAKLRNPHLLLFMGACT-AP 241 Query 682 ENI-MVTEYVEHGPLDVWLRRER---GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737 E++ +VTE + G + LR + + +++A+ +++L N++H ++ Sbjct 242 EDLSIVTELMPKGSVHSLLRAKEDTSDFITFKRAILIARDTVLGMTWLHASNILHLDLKP 301 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI-------PWLAPECLPGGANS 790 N+L+ + + +K++D GL + + +++ ++APE L Sbjct 302 ANLLVDQ-------NWVVKVAD--FGLSKYMKPDSKDKLLGQAGSPLYMAPEMLVN--QP 350 Query 791 LSTAMDKWGFGATLLEICFDGE--APLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTS 846 +D + F L E+ E L S P E +++R +P+ +L L + Sbjct 351 YDGKVDVFSFSILLWELLTKQEPYNKLYSSYPQLVEGVVNKKNRPIIPDYFPTRLKDLLA 410 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906 +C + P++RPSF I + R+ L D L ++ +S + + Y+ K Sbjct 411 RCWDHYPSRRPSFAEISKQ--RILETILIDGLILD----SSARQFWSQYYMGKEEVPWNS 464 Query 907 HFGKVSLYCYDPTNDGTGEMVAVKALK 933 SLYC +N + + + +K LK Sbjct 465 FIVNFSLYCGFESN-LSADDIKIKFLK 490 >sp|Q55CE0|MKCF_DICDI Probable serine/threonine-protein kinase mkcF OS=Dictyostelium discoideum OX=44689 GN=mkcF PE=3 SV=1 Length=677 Score = 95.1 bits (235), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 89/325 (27%), Positives = 144/325 (44%), Gaps = 39/325 (12%) Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923 R LT + L T P+SD K+ +K +G G +GKV YD Sbjct 372 RILTGISTEFLGQASTTIRVIPSSDI----KKRIKFTHMVGRGQYGKVYDALYDK----- 422 Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 + V VK + P+ + QEI L H +I+KY C L +V E++ Sbjct 423 -KRVCVKVVNYST-PKEQHNVLQEIGFLTQCDHPNILKYN--CSVLYGSDLFIVSEFIQG 478 Query 984 GSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 G+L H Q+ ++ + ++YLH + IHRD+ A NV++ D VK+ DF Sbjct 479 GTLEQASASSHVFKETQVGFIGLELLKAISYLHEKKLIHRDIKAANVMVSTDGEVKLIDF 538 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 GL +V +G + V SP ++ +PE ++ + Y SD+WSFG+ + ELL + Sbjct 539 GLCASVEKGGSQHMV----GSP-YYMSPEMIRGEECSYPSDIWSFGICILELLF-----K 588 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 PP + +M + + G P+ +C ++ ++ C+E+ R T Sbjct 589 KPPHR--------DSRMKAMFYNAI--NGIDFPKI-RCSIDLKDMLWQCFESNPEKRSTV 637 Query 1163 ENLI--PILKTVHEKYQGQAPSVFS 1185 + L+ P K K Q SVF+ Sbjct 638 DKLMRHPFFKRCESK--SQMKSVFT 660 Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 53/233 (23%), Positives = 100/233 (43%), Gaps = 20/233 (9%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 RV +KV++ S + ++Q H ++ + + G + +V+E+++ G L+ Sbjct 424 RVCVKVVNYSTPKEQHNVLQEIGFLTQCDHPNILKYNCSVLYGSDLFIVSEFIQGGTLEQ 483 Query 698 WLRRERGHVPMAWKM-VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 HV ++ + +L A+SYL K L+H ++ N++++ G +K Sbjct 484 A--SASSHVFKETQVGFIGLELLKAISYLHEKKLIHRDIKAANVMVSTDGE-------VK 534 Query 757 LSDPGV--GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 L D G+ + + V +++PE + G S D W FG +LE+ F Sbjct 535 LIDFGLCASVEKGGSQHMVGSPYYMSPEMIRG--EECSYPSDIWSFGICILELLFKKPPH 592 Query 815 LQSRSPSEKEHFYQRQHRL--PEPSCP-QLATLTSQCLTYEPTQRPSFRTILR 864 SR K FY + + P+ C L + QC P +R + ++R Sbjct 593 RDSRM---KAMFYNAINGIDFPKIRCSIDLKDMLWQCFESNPEKRSTVDKLMR 642 >sp|A4K2Q5|STK4_OTOGA Serine/threonine-protein kinase 4 OS=Otolemur garnettii OX=30611 GN=STK4 PE=3 SV=1 Length=487 Score = 94.0 bits (232), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V Y + TG++VA+K + + Q +EI I++ H+ Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 201 YNCVADIWSLGITAIEM 217 Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q H+ +G + + +V EY G + +R + + Q Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL +H ++ NILL G A KL+D GV +++ V Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187 Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830 P W+APE + G N ++ D W G T +E+ +G+ P P Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R PE QCL P QR + +L+ Sbjct 244 FRKPELWSDNFTDFVRQCLVKSPDQRATATQLLQ 277 >sp|Q5E9L6|STK4_BOVIN Serine/threonine-protein kinase 4 OS=Bos taurus OX=9913 GN=STK4 PE=2 SV=1 Length=487 Score = 94.0 bits (232), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V Y + TG++VA+K + + Q +EI I++ H+ Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 201 YNCVADIWSLGITAIEM 217 Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q H+ +G + + +V EY G + +R + + Q Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL +H ++ NILL G A KL+D GV +++ V Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187 Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830 P W+APE + G N ++ D W G T +E+ +G+ P P Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R PE QCL P QR + +L+ Sbjct 244 FRKPELWSDSFMDFVKQCLVKSPEQRATATQLLQ 277 >sp|A4K2S1|STK4_LEMCA Serine/threonine-protein kinase 4 OS=Lemur catta OX=9447 GN=STK4 PE=3 SV=1 Length=487 Score = 94.0 bits (232), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V Y + TG++VA+K + + Q +EI I++ H+ Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFM 143 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 201 YNCVADIWSLGITAIEM 217 Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 52/214 (24%), Positives = 80/214 (37%), Gaps = 20/214 (9%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q H+ +G + + +V EY G + +R + + Q Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTL 134 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL +H ++ NILL G A KL+D GV +++ V Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187 Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830 P W+APE + G N ++ D W G T +E+ +G+ P P Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R PE QCL P QR + +L+ Sbjct 244 FRKPELWSDNFMDFVRQCLVKSPDQRATATQLLQ 277 >sp|Q96L34|MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 OS=Homo sapiens OX=9606 GN=MARK4 PE=1 SV=1 Length=752 Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 72/215 (33%), Positives = 105/215 (49%), Gaps = 16/215 (7%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSG 943 P P V + R L R +G+G+F KV L + TG VA+K + K P Sbjct 50 PEEQPHVGNYRLL---RTIGKGNFAKVKLARHI----LTGREVAIKIIDKTQLNPSSLQK 102 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLL 1002 +E+ I++ L H +I+K E EK+L LVMEY G + DYL H + + Sbjct 103 LFREVRIMKGLNHPNIVKLFEVIET--EKTLYLVMEYASAGEVFDYLVSHGRMKEKEARA 160 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 +QI + Y H ++ +HRDL A N+LLD + +KI DFG + G + G Sbjct 161 KFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTF--CGS 218 Query 1063 SPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096 P + APE + K+ D+WS GV LY L++ Sbjct 219 PP--YAAPELFQGKKYDGPEVDIWSLGVILYTLVS 251 Score = 40.8 bits (94), Expect = 0.086, Method: Compositional matrix adjust. Identities = 52/236 (22%), Positives = 97/236 (41%), Gaps = 22/236 (9%) Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K++D + + + + +M ++H ++ + V +V EY G + Sbjct 85 VAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVF 144 Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 +L H M K A+ Q+ SA+ Y KN+VH ++ N+LL AE Sbjct 145 DYLV---SHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD----AEAN--- 194 Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 IK++D G + +++ P+ APE G +D W G L + Sbjct 195 IKIADFGFS-NEFTLGSKLDTFCGSPPYAAPELFQGKKYD-GPEVDIWSLGVILYTL-VS 251 Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 G P + E +E + ++R+P ++ + L P +R + I++D Sbjct 252 GSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKD 307 >sp|Q9FIL7|CRCK1_ARATH Calmodulin-binding receptor-like cytoplasmic kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CRCK1 PE=1 SV=1 Length=470 Score = 93.6 bits (231), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 68/204 (33%), Positives = 102/204 (50%), Gaps = 14/204 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK-ALKADCGPQHRSGWKQEIDILRTLYHEH 958 + +GEG FG V D DGT +VA+K A K + G +K EI L + H + Sbjct 150 VHQIGEGGFGTVFKGKLD---DGT--IVAIKRARKNNYGKSWLLEFKNEIYTLSKIEHMN 204 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLH 1015 ++K G E EK + V+EYV G+LR++L + + +A+ L A + + YLH Sbjct 205 LVKLYGFLEHGDEKVI--VVEYVANGNLREHLDGLRGNRLEMAERLEIAIDVAHALTYLH 262 Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 IHRD+ A N+L+ N K+ DFG A+ V E + + P+ Sbjct 263 TYTDSPIIHRDIKASNILITNKLRAKVADFGFARLVSEDLGATHISTQVKGSAGYVDPDY 322 Query 1073 LKEYKFYYASDVWSFGVTLYELLT 1096 L+ ++ SDV+SFGV L E+LT Sbjct 323 LRTFQLTDKSDVYSFGVLLVEILT 346 Score = 56.2 bits (134), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 55/238 (23%), Positives = 102/238 (43%), Gaps = 28/238 (12%) Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWK 711 L F +S++ H +L ++G G E ++V EYV +G L L RG+ + MA + Sbjct 188 LEFKNEIYTLSKIEHMNLVKLYGFLEHGDEKVIVVEYVANGNLREHLDGLRGNRLEMAER 247 Query 712 MVVAQQLASALSYLENKN---LVHGNVCGRNILLA-RLGLAEGTSPFIKLSDPGVGLGAL 767 + +A +A AL+YL ++H ++ NIL+ +L F +L +G + Sbjct 248 LEIAIDVAHALTYLHTYTDSPIIHRDIKASNILITNKLRAKVADFGFARLVSEDLGATHI 307 Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF- 826 S + + ++ P+ L L+ D + FG L+EI G P++ + P + Sbjct 308 STQVKGS-AGYVDPDYLR--TFQLTDKSDVYSFGVLLVEI-LTGRRPIELKRPRKDRLTV 363 Query 827 ------------------YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 + +++R ++ L S+C+T RP+ + I L Sbjct 364 KWALRRLKDDEAVLIMDPFLKRNRAAIEVAEKMLRLASECVTPTRATRPAMKGIAEKL 421 >sp|Q9V3Q6|M3K7_DROME Mitogen-activated protein kinase kinase kinase 7 OS=Drosophila melanogaster OX=7227 GN=Tak1 PE=2 SV=1 Length=678 Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 77/283 (27%), Positives = 131/283 (46%), Gaps = 38/283 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G +G V + ++VAVK A + ++E+ L + H +II Sbjct 25 VGHGSYGVVCKAVW------RDKLVAVKEFFASA---EQKDIEKEVKQLSRVKHPNIIAL 75 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA--- 1016 G Q ++ L+ME+ GSL ++L + + LA + +A+Q EG+AYLHA Sbjct 76 HGISSYQ--QATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMTP 133 Query 1017 QHYIHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + IHRD+ N+LL N R +KI DFG + + + W APE + Sbjct 134 KPLIHRDVKPLNLLLTNKGRNLKICDFGTVA------DKSTMMTNNRGSAAWMAPEVFEG 187 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 K+ D++S+ + L+E+L S+ P K ++ Q + + +GER P Sbjct 188 SKYTEKCDIFSWAIVLWEVL-----SRKQPFKGIDNAYTIQWK---------IYKGERPP 233 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 CP + LM CW+T RP+ + ++ ++ + + Y G Sbjct 234 LLTTCPKRIEDLMTACWKTVPEDRPSMQYIVGVMHEIVKDYTG 276 Score = 42.7 bits (99), Expect = 0.023, Method: Compositional matrix adjust. Identities = 47/209 (22%), Positives = 85/209 (41%), Gaps = 15/209 (7%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLAS 720 +S+V H ++ +HG+ ++ E+ E G L +L + + +A M A+Q A Sbjct 64 LSRVKHPNIIALHGISSYQQATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAE 123 Query 721 ALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP 777 L+YL K L+H +V N+LL G F ++D + Sbjct 124 GLAYLHAMTPKPLIHRDVKPLNLLLTNKGRNLKICDFGTVADKSTMM-----TNNRGSAA 178 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ--SRSPSEKEHFYQRQHRLPE 835 W+APE G + + W A +L + P + + + + Y+ + Sbjct 179 WMAPEVFEGSKYTEKCDIFSW---AIVLWEVLSRKQPFKGIDNAYTIQWKIYKGERPPLL 235 Query 836 PSCPQ-LATLTSQCLTYEPTQRPSFRTIL 863 +CP+ + L + C P RPS + I+ Sbjct 236 TTCPKRIEDLMTACWKTVPEDRPSMQYIV 264 >sp|D3ZGQ5|NEK8_RAT Serine/threonine-protein kinase Nek8 OS=Rattus norvegicus OX=10116 GN=Nek8 PE=1 SV=1 Length=698 Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 64/203 (32%), Positives = 108/203 (53%), Gaps = 17/203 (8%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYH 956 ++IR +G G FG V L C + ++V +K + + + R + E +L+ L H Sbjct 5 ERIRVVGRGAFGIVHL-CLRKADQ---KLVIIKQIPVEQMTKEERQAAQNECQVLKLLNH 60 Query 957 EHIIKY-KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMA 1012 ++I+Y + ED K+L + MEY P G+L +++ + L + +L F QI + Sbjct 61 PNVIEYYENFLED---KALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALH 117 Query 1013 YLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 ++H +HRDL +N+LLD R+ VKIGDFG++K + + Y V +P + +PE Sbjct 118 HVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVV---GTPCY-ISPE 173 Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094 + + SD+W+ G LYEL Sbjct 174 LCEGKPYNQKSDIWALGCVLYEL 196 >sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens OX=9606 GN=LIMK1 PE=1 SV=3 Length=647 Score = 94.7 bits (234), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 80/292 (27%), Positives = 135/292 (46%), Gaps = 33/292 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+ T+ TGE++ +K L R+ + +E+ ++R L H +++K+ Sbjct 345 LGKGCFGQA----IKVTHRETGEVMVMKELIRFDEETQRT-FLKEVKVMRCLEHPNVLKF 399 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYI 1020 G +K L + EY+ G+LR + +Q + FA+ I GMAYLH+ + I Sbjct 400 IGVLYK--DKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNII 457 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLA------KAVPEGHEYYRV--REDGDSPV---FWYA 1069 HRDL + N L+ ++ V + DFGLA K PEG + R+ + V +W A Sbjct 458 HRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMA 517 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE + + DV+SFG+ L E++ ++ + ++ L + L+ Sbjct 518 PEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDF---------GLNVRGFLD 568 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 R P CP + + C + + RP+F L L+T+ G P Sbjct 569 RY----CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHLP 616 Score = 67.4 bits (163), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 66/266 (25%), Positives = 113/266 (42%), Gaps = 33/266 (12%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +V+K L + F + +M + H ++ GV + +TEY++ G L Sbjct 365 MVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGI 424 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL-------------LARL 745 ++ P + ++ A+ +AS ++YL + N++H ++ N L LARL Sbjct 425 IKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARL 484 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAMDKWG 799 + E T P GL +L + +R +R W+APE + G S +D + Sbjct 485 MVDEKTQP--------EGLRSLKKPDRKKRYTVVGNPYWMAPEMING--RSYDEKVDVFS 534 Query 800 FGATLLEIC--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSC-PQLATLTSQCLTYEPTQR 856 FG L EI + + R+ + R P+C P +T +C +P +R Sbjct 535 FGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKR 594 Query 857 PSFRTILRDLTRLQPHNLADVLTVNP 882 PSF + L L+ H LA L + P Sbjct 595 PSFVKLEHWLETLRMH-LAGHLPLGP 619 >sp|Q8CIP4|MARK4_MOUSE MAP/microtubule affinity-regulating kinase 4 OS=Mus musculus OX=10090 GN=Mark4 PE=1 SV=1 Length=752 Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 72/215 (33%), Positives = 105/215 (49%), Gaps = 16/215 (7%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSG 943 P P V + R L R +G+G+F KV L + T G VA+K + K P Sbjct 50 PEEQPHVGNYRLL---RTIGKGNFAKVKLARHILT----GREVAIKIIDKTQLNPSSLQK 102 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLL 1002 +E+ I++ L H +I+K E EK+L LVMEY G + DYL H + + Sbjct 103 LFREVRIMKGLNHPNIVKLFEVIET--EKTLYLVMEYASAGEVFDYLVSHGRMKEKEARA 160 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 +QI + Y H ++ +HRDL A N+LLD + +KI DFG + G + G Sbjct 161 KFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTF--CGS 218 Query 1063 SPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096 P + APE + K+ D+WS GV LY L++ Sbjct 219 PP--YAAPELFQGKKYDGPEVDIWSLGVILYTLVS 251 Score = 41.2 bits (95), Expect = 0.073, Method: Compositional matrix adjust. Identities = 52/236 (22%), Positives = 97/236 (41%), Gaps = 22/236 (9%) Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K++D + + + + +M ++H ++ + V +V EY G + Sbjct 85 VAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVF 144 Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 +L H M K A+ Q+ SA+ Y KN+VH ++ N+LL AE Sbjct 145 DYLV---SHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD----AEAN--- 194 Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 IK++D G + +++ P+ APE G +D W G L + Sbjct 195 IKIADFGFS-NEFTLGSKLDTFCGSPPYAAPELFQGKKYD-GPEVDIWSLGVILYTL-VS 251 Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 G P + E +E + ++R+P ++ + L P +R + I++D Sbjct 252 GSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKD 307 >sp|Q86SG6|NEK8_HUMAN Serine/threonine-protein kinase Nek8 OS=Homo sapiens OX=9606 GN=NEK8 PE=1 SV=1 Length=692 Score = 94.7 bits (234), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 64/203 (32%), Positives = 108/203 (53%), Gaps = 17/203 (8%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYH 956 ++IR +G G FG V L C + ++V +K + + + R + E +L+ L H Sbjct 5 ERIRVVGRGAFGIVHL-CLRKADQ---KLVIIKQIPVEQMTKEERQAAQNECQVLKLLNH 60 Query 957 EHIIKY-KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMA 1012 ++I+Y + ED K+L + MEY P G+L +++ + L + +L F QI + Sbjct 61 PNVIEYYENFLED---KALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALH 117 Query 1013 YLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 ++H +HRDL +N+LLD R+ VKIGDFG++K + + Y V +P + +PE Sbjct 118 HVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVV---GTPCY-ISPE 173 Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094 + + SD+W+ G LYEL Sbjct 174 LCEGKPYNQKSDIWALGCVLYEL 196 >sp|Q5E9Y0|CDK2_BOVIN Cyclin-dependent kinase 2 OS=Bos taurus OX=9913 GN=CDK2 PE=2 SV=1 Length=298 Score = 90.9 bits (224), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 68/207 (33%), Positives = 104/207 (50%), Gaps = 19/207 (9%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955 +K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ L Sbjct 4 FQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYV--PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013 H +I+K E L LV E++ L D I L + + Q+ +G+A+ Sbjct 60 HPNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAF 117 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070 H+ +HRDL +N+L++ D +K+ DFGLA+A VP + V WY AP Sbjct 118 CHSHRVLHRDLKPQNLLINADGSIKLADFGLARAFGVPVRTYTHEVV------TLWYRAP 171 Query 1071 ECLKEYKFY-YASDVWSFGVTLYELLT 1096 E L K+Y A D+WS G E++T Sbjct 172 EILLGCKYYSTAVDIWSLGCIFAEMVT 198 Score = 35.8 bits (81), Expect = 2.0, Method: Compositional matrix adjust. Identities = 55/251 (22%), Positives = 103/251 (41%), Gaps = 46/251 (18%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 SL+ +++H ++ + V + +V E++ +P+ QL Sbjct 53 SLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLL 112 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREERVER 775 L++ + ++H ++ +N+L+ A+G+ IKL+D G+ G+ + V Sbjct 113 QGLAFCHSHRVLHRDLKPQNLLIN----ADGS---IKLADFGLARAFGVPVRTYTHEVVT 165 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQS------RSPSEKE 824 + + APE L G STA+D W G E+ F G++ + + E Sbjct 166 LWYRAPEIL-LGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDE 224 Query 825 HFYQRQHRLPE--PSCPQLA----------------TLTSQCLTYEPTQRPSFRTIL--- 863 + +P+ PS P+ A +L SQ L Y+P +R S + L Sbjct 225 VVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHP 284 Query 864 --RDLTRLQPH 872 +D+T+ PH Sbjct 285 FFQDVTKPVPH 295 >sp|A4K2P5|STK4_COLGU Serine/threonine-protein kinase 4 OS=Colobus guereza OX=33548 GN=STK4 PE=3 SV=1 Length=487 Score = 94.0 bits (232), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V Y + TG++VA+K + + Q +EI I++ H+ Sbjct 33 LEKLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 85 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 86 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLQSTLKGLEYLHFM 143 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 144 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 200 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 201 YNCVADIWSLGITAIEM 217 Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 53/214 (25%), Positives = 80/214 (37%), Gaps = 20/214 (9%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q H+ +G + + +V EY G + +R + V Q Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLQSTL 134 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL +H ++ NILL G A KL+D GV +++ V Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 187 Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830 P W+APE + G N ++ D W G T +E+ +G+ P P Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 243 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R PE QCL P QR + +L+ Sbjct 244 FRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQ 277 >sp|P46573|PBL10_ARATH Probable serine/threonine-protein kinase PBL10 OS=Arabidopsis thaliana OX=3702 GN=PBL10 PE=1 SV=2 Length=412 Score = 92.8 bits (229), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 87/288 (30%), Positives = 132/288 (46%), Gaps = 24/288 (8%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LGEG FG V D + GTG ++AVK L D G Q W E++ L H Sbjct 75 LGEGGFGSVFKGWIDEQTLTASKPGTGVVIAVKKLNQD-GWQGHQEWLAEVNYLGQFSHP 133 Query 958 HIIKYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGM 1011 +++K G C ED+ LV E++P GSL ++L R L L A +G+ Sbjct 134 NLVKLIGYCLEDEHR---LLVYEFMPRGSLENHLFRRGSYFQPLSWTLRLKVALGAAKGL 190 Query 1012 AYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 A+LH I+RD N+LLD++ K+ DFGLAK P G + + V + A Sbjct 191 AFLHNAETSVIYRDFKTSNILLDSEYNAKLSDFGLAKDGPTGDKSH-VSTRIMGTYGYAA 249 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT---HCDSSQSPPTKFLELIGIAQGQMTVLR-LT 1125 PE L SDV+S+GV L E+L+ D ++ P + +L+ A+ + R L Sbjct 250 PEYLATGHLTTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQ--KLVEWARPLLANKRKLF 307 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 +++ + + C+V L C E RP ++ L+ + Sbjct 308 RVIDNRLQDQYSMEEACKVATLALRCLTFEIKLRPNMNEVVSHLEHIQ 355 Score = 59.7 bits (143), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 86/348 (25%), Positives = 146/348 (42%), Gaps = 66/348 (19%) Query 568 RASPRTL-------NLSQLSFH--RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618 R +PRT NL +F + + S LG+G +V++G + Sbjct 39 RTNPRTEGEILQSPNLKSFTFAELKAATRNFRPDSVLGEGGFGSVFKGWI---------- 88 Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678 DE L + G + + +K L+ + + + Q SH +L + G C+ Sbjct 89 ----DEQTLTASKP-GTGVVIAVKKLNQDGWQGHQEWLAEVNYLGQFSHPNLVKLIGYCL 143 Query 679 RGPENIMVTEYVEHGPLDVWL-RRERGHVPMAW--KMVVAQQLASALSYLEN--KNLVHG 733 ++V E++ G L+ L RR P++W ++ VA A L++L N ++++ Sbjct 144 EDEHRLLVYEFMPRGSLENHLFRRGSYFQPLSWTLRLKVALGAAKGLAFLHNAETSVIYR 203 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVE-RI----PWLAPECLPGG 787 + NILL + KLSD G+ G + V RI + APE L G Sbjct 204 DFKTSNILL-------DSEYNAKLSDFGLAKDGPTGDKSHVSTRIMGTYGYAAPEYLATG 256 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--------------------EHFY 827 L+T D + +G LLE+ A ++R P E+ ++ Sbjct 257 --HLTTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLLANKRKLFRVIDNRL 314 Query 828 QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 Q Q+ + E +C ++ATL +CLT+E RP+ ++ L +Q N A Sbjct 315 QDQYSMEE-AC-KVATLALRCLTFEIKLRPNMNEVVSHLEHIQTLNEA 360 >sp|Q9FX43|M2K9_ARATH Mitogen-activated protein kinase kinase 9 OS=Arabidopsis thaliana OX=3702 GN=MKK9 PE=1 SV=1 Length=310 Score = 91.3 bits (225), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 65/208 (31%), Positives = 104/208 (50%), Gaps = 20/208 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+K+ LG G+ G V Y + T E+ A+K + D P +E++ILR Sbjct 47 LEKLNVLGCGNGGIV----YKVRHKTTSEIYALKTVNGDMDPIFTRQLMREMEILRRTDS 102 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016 +++K G E + ++MEY+ G+L R + +L FA+QI +G++YLHA Sbjct 103 PYVVKCHGIFEKPVVGEVSILMEYMDGGTLESL--RGGVTEQKLAGFAKQILKGLSYLHA 160 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---FWYAPE-- 1071 +HRD+ N+LL++ VKI DFG++K + R + +S V + +PE Sbjct 161 LKIVHRDIKPANLLLNSKNEVKIADFGVSKIL------VRSLDSCNSYVGTCAYMSPERF 214 Query 1072 ---CLKEYKFYYASDVWSFGVTLYELLT 1096 YA D+WSFG+ + ELL Sbjct 215 DSESSGGSSDIYAGDIWSFGLMMLELLV 242 >sp|Q54QQ1|PHG2_DICDI Serine/threonine-protein kinase phg2 OS=Dictyostelium discoideum OX=44689 GN=phg2 PE=1 SV=1 Length=1387 Score = 95.5 bits (236), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 71/292 (24%), Positives = 133/292 (46%), Gaps = 34/292 (12%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLY 955 L+ I+ +G G + KV Y + VA+K ++ ++ + +K+E DIL T+ Sbjct 807 LEYIKRIGSGTYSKVYKGKY------RDKFVAIKTMRGSNMTTEQIESFKKECDILSTIQ 860 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAY 1013 +I + G C ++ + L +V+EY G+L L P + + ++ EG+ Y Sbjct 861 SPLLISFYGSCIEESQ--LSMVVEYCSKGTLHKVLNNPLLDFDWDKWFKWMTEVVEGVRY 918 Query 1014 LHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 LH+ + +HRDL N+L+ +D K+ DFGL + + + G + + APE Sbjct 919 LHSMNPPMVHRDLKTLNILISSDWTAKLCDFGLTRTMTMTNVSTLGMLRGT--MAYTAPE 976 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSS-------QSPPTKFLELIGIAQGQMTVLRL 1124 F SDV+S GV ++E + C S + P + +++I + ++ Sbjct 977 IYDGLLFNTKSDVYSLGVIMWEAIQRCISGVYLRPFHEHPISMDIQIIILTSKNKVRPKI 1036 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 +E CP ++ L+ CW+ RP + ++ IL T+ + + Sbjct 1037 SE------------NCPEQLKTLITRCWDENPDKRPNCDEILEILLTMKQAH 1076 >sp|Q7SY52|STK10_DANRE Serine/threonine-protein kinase 10 OS=Danio rerio OX=7955 GN=stk10 PE=2 SV=1 Length=974 Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 63/202 (31%), Positives = 104/202 (51%), Gaps = 17/202 (8%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I +LG+G FGKV Y N TG + A K ++ + + EIDIL + H++I Sbjct 40 IGELGDGAFGKV----YKAQNKETGVLAAAKVIETK-SEEELEDYMVEIDILASCNHQYI 94 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQ 1017 +K + L +++E+ P G++ + GL Q+ + +Q+ E + YLH+ Sbjct 95 VKLLDAF--FFDNKLSIMIEFCPGGAVDAIMLELDRGLQEPQIRVICKQMLEALQYLHSM 152 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP-----EC 1072 IHRDL A N+LL D +K+ DFG++ + + + R+ +W AP E Sbjct 153 KIIHRDLKAGNILLTLDGDIKLADFGVS---AKNTKTLQRRDSFIGTPYWMAPEVVMCET 209 Query 1073 LKEYKFYYASDVWSFGVTLYEL 1094 +K+ + Y +D+WS G+TL EL Sbjct 210 MKDAPYDYKADIWSLGITLIEL 231 Score = 42.4 bits (98), Expect = 0.036, Method: Compositional matrix adjust. Identities = 32/103 (31%), Positives = 45/103 (44%), Gaps = 14/103 (14%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV---GLGALSR 769 V+ +Q+ AL YL + ++H ++ NILL G IKL+D GV L R Sbjct 137 VICKQMLEALQYLHSMKIIHRDLKAGNILLTLDG-------DIKLADFGVSAKNTKTLQR 189 Query 770 EERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808 + P W+APE C D W G TL+E+ Sbjct 190 RDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIELA 232 >sp|P46549|SULU_CAEEL Serine/threonine-protein kinase SULU OS=Caenorhabditis elegans OX=6239 GN=kin-18 PE=1 SV=1 Length=982 Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 69/209 (33%), Positives = 106/209 (51%), Gaps = 24/209 (11%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDI 950 +RY + +R++G G FG V + YD N+ T VA+K + G Q W +E+ Sbjct 28 QRY-QDLREIGHGSFGAV-YFAYDKKNEQT---VAIKKMNF-SGKQAVEKWNDILKEVSF 81 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQIC 1008 L T+ H HI+ YK C + + LVMEY +GS D + G+ ++ + A Q Sbjct 82 LNTVVHPHIVDYKACF--LKDTTCWLVMEYC-IGSAADIVDVLRKGMREVEIAAICSQTL 138 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 + + YLH+ IHRD+ A N+LL + +VK+ DFG A V + +P F+ Sbjct 139 DALRYLHSLKRIHRDIKAGNILLSDHAIVKLADFGSASLVDPAQTFI------GTP-FFM 191 Query 1069 APE---CLKEYKFYYASDVWSFGVTLYEL 1094 APE + E + +D+WS G+T EL Sbjct 192 APEVILAMDEGHYTDRADIWSLGITCIEL 220 >sp|P0C5E2|LRL12_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 1.2 OS=Arabidopsis thaliana OX=3702 GN=LRK10L-1.2 PE=2 SV=3 Length=651 Score = 94.4 bits (233), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 82/295 (28%), Positives = 134/295 (45%), Gaps = 18/295 (6%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 ++LG+G FG V Y DG VAVK L D + ++ E++IL L H +++ Sbjct 345 KELGDGGFGTVY---YGKLKDGRS--VAVKRL-YDNNFKRAEQFRNEVEILTGLRHPNLV 398 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PR---HSIGLAQLLLFAQQICEGMAYLH 1015 GC Q + L LV EYV G+L D+L P+ S+ + L A + + YLH Sbjct 399 ALFGCSSKQS-RDLLLVYEYVANGTLADHLHGPQANPSSLPWSIRLKIAVETASALKYLH 457 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 A IHRD+ + N+LLD + VK+ DFGL++ P + G + P+ Sbjct 458 ASKIIHRDVKSNNILLDQNFNVKVADFGLSRLFPMDKTHVSTAPQGTPG--YVDPDYHLC 515 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERG--- 1131 Y+ SDV+SF V L EL++ + + P + + L +A ++ L ++++ Sbjct 516 YQLSNKSDVYSFAVVLMELISSLPAVDITRPRQEINLSNMAVVKIQNHELRDMVDPSLGF 575 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 + R + V L C +++ RP ++ L + G V V Sbjct 576 DTDTRVRQTVIAVAELAFQCLQSDKDLRPCMSHVQDTLTRIQNNGFGSEMDVVDV 630 Score = 54.7 bits (130), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 69/282 (24%), Positives = 115/282 (41%), Gaps = 47/282 (17%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM-VTEYVEHGPLDV 697 V +K L ++ A F +++ + H +L + G + +++ V EYV +G L Sbjct 366 VAVKRLYDNNFKRAEQFRNEVEILTGLRHPNLVALFGCSSKQSRDLLLVYEYVANGTLAD 425 Query 698 WLRRERGH---VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 L + + +P + ++ +A + ASAL YL ++H +V NILL + + Sbjct 426 HLHGPQANPSSLPWSIRLKIAVETASALKYLHASKIIHRDVKSNNILLDQ-------NFN 478 Query 755 IKLSDPGVGLGALSREERVERI-PWLAPECLPGGAN-------SLSTAMDKWGFGATLLE 806 +K++D G LSR +++ AP+ PG + LS D + F L+E Sbjct 479 VKVADFG-----LSRLFPMDKTHVSTAPQGTPGYVDPDYHLCYQLSNKSDVYSFAVVLME 533 Query 807 I-----CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL---------------ATLTS 846 + D P Q + S + H L + P L A L Sbjct 534 LISSLPAVDITRPRQEINLSNMAVVKIQNHELRDMVDPSLGFDTDTRVRQTVIAVAELAF 593 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLA---DVLTVNPDSP 885 QCL + RP + LTR+Q + DV+ VN P Sbjct 594 QCLQSDKDLRPCMSHVQDTLTRIQNNGFGSEMDVVDVNKSGP 635 >sp|Q9SAJ2|RAF20_ARATH RAF-like serine/threonine-protein kinase 20 OS=Arabidopsis thaliana OX=3702 GN=RAF20 PE=1 SV=1 Length=1248 Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 88/297 (30%), Positives = 131/297 (44%), Gaps = 39/297 (13%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---- 946 + L+++R+LG G FG V + G VA+K +K C S ++ Sbjct 958 IIKNEDLEELRELGSGTFGTVYHGKW------RGSDVAIKRIKKSCFAGRSSEQERLTGE 1011 Query 947 ---EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLL 1001 E +IL L+H +++ + G +D +L V EY+ GSLR L R L + L Sbjct 1012 FWGEAEILSKLHHPNVVAFYGVVKDGPGGTLATVTEYMVDGSLRHVLVRKDRHLDRRKRL 1071 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDR-LVKIGDFGLAKAVPEGHEYYRV 1057 + A GM YLH+++ +H DL N+L+ D R + K+GDFGL+K V Sbjct 1072 IIAMDAAFGMEYLHSKNTVHFDLKCDNLLVNLKDPSRPICKVGDFGLSKIKRNTLVSGGV 1131 Query 1058 REDGDSPVFWYAPECLK--EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 R G P W APE L K DV+SFG+ L+E+LT + P + I Sbjct 1132 R--GTLP--WMAPELLNGSSSKVSEKVDVFSFGIVLWEILTGEE-----PYANMHYGAII 1182 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 G ++ R P C E LM+ CW RP+F + L+ + Sbjct 1183 GG---------IVNNTLRPTIPGFCDDEWRTLMEECWAPNPMARPSFTEIAGRLRVM 1230 Score = 79.3 bits (194), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 79/301 (26%), Positives = 125/301 (42%), Gaps = 58/301 (19%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + +++ +L LG GT VY G+ R D ++ + GR QE Sbjct 959 IKNEDLEELRELGSGTFGTVYHGKWR---GSDVAIKRI--KKSCFAGRSSEQER------ 1007 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEYVEHGPLDVWLRR 701 + F+ A ++S++ H ++ +GV GP + VTEY+ G L L R Sbjct 1008 -------LTGEFWGEAEILSKLHHPNVVAFYGVVKDGPGGTLATVTEYMVDGSLRHVLVR 1060 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 + H+ ++++A A + YL +KN VH ++ N+L + L + + P K+ D Sbjct 1061 KDRHLDRRKRLIIAMDAAFGMEYLHSKNTVHFDLKCDNLL---VNLKDPSRPICKVGD-- 1115 Query 762 VGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 GL + R V +PW+APE L G ++ +S +D + FG L EI GE P Sbjct 1116 FGLSKIKRNTLVSGGVRGTLPWMAPELLNGSSSKVSEKVDVFSFGIVLWEI-LTGEEP-- 1172 Query 817 SRSPSEKEHFYQRQH----------RLPEPSCP-----QLATLTSQCLTYEPTQRPSFRT 861 Y H P+ P + TL +C P RPSF Sbjct 1173 ----------YANMHYGAIIGGIVNNTLRPTIPGFCDDEWRTLMEECWAPNPMARPSFTE 1222 Query 862 I 862 I Sbjct 1223 I 1223 >sp|Q6ZMQ8|LMTK1_HUMAN Serine/threonine-protein kinase LMTK1 OS=Homo sapiens OX=9606 GN=AATK PE=1 SV=2 Length=1374 Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 69/220 (31%), Positives = 106/220 (48%), Gaps = 20/220 (9%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG-TGEMVAVKALKADCGPQHRSGWKQEI 948 T + L ++++G G FGKV L N G + V VK L+A Q + + +E+ Sbjct 118 TDVGRHSLLYLKEIGRGWFGKVFL---GEVNSGISSAQVVVKELQASASVQEQMQFLEEV 174 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA------QLLL 1002 R L H ++++ C + LVME+ PLG L+ YL + + L Sbjct 175 QPYRALKHSNLLQCLAQCAEV--TPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPRTLQR 232 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 A ++ G+ +LH +++H DLA RN LL D VKIGD+GLA +Y+ + Sbjct 233 MACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCK-YREDYFVTADQLW 291 Query 1063 SPVFWYAPECLKEYKFYY-------ASDVWSFGVTLYELL 1095 P+ W APE + E + +VWS GVT++EL Sbjct 292 VPLRWIAPELVDEVHSNLLVVDQTKSGNVWSLGVTIWELF 331 Score = 35.0 bits (79), Expect = 6.5, Method: Compositional matrix adjust. Identities = 60/248 (24%), Positives = 99/248 (40%), Gaps = 31/248 (13%) Query 638 RVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +VV+K L S + F E + H++L C ++V E+ G L Sbjct 152 QVVVKELQASASVQEQMQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLK 211 Query 697 VWLRRERGHVPMAWKMVVAQQLASALS----YLENKNLVHGNVCGRNILLARLGLAEGTS 752 +LR R MA Q++A ++ +L N VH ++ RN LL A+ T Sbjct 212 GYLRSCRVAESMAPDPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLT----ADLT- 266 Query 753 PFIKLSDPGVGLGALSREERVER----IP--WLAPECLPGGANSL-----STAMDKWGFG 801 +K+ D G+ + V +P W+APE + ++L + + + W G Sbjct 267 --VKIGDYGLAHCKYREDYFVTADQLWVPLRWIAPELVDEVHSNLLVVDQTKSGNVWSLG 324 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTS-------QCLTYEPT 854 T+ E+ G P S + + R+ +L P PQL S Q +P Sbjct 325 VTIWELFELGTQPYPQHSDQQVLAYTVREQQLKLPK-PQLQLTLSDRWYEVMQFCWLQPE 383 Query 855 QRPSFRTI 862 QRP+ + Sbjct 384 QRPTAEEV 391 >sp|Q9SIT1|TMK3_ARATH Receptor-like kinase TMK3 OS=Arabidopsis thaliana OX=3702 GN=TMK3 PE=1 SV=1 Length=943 Score = 95.1 bits (235), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 69/205 (34%), Positives = 99/205 (48%), Gaps = 21/205 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 LG G FG V +DGT +AVK +++ + + +K EI +L + H H++ Sbjct 591 LGRGGFGTV---YKGELHDGT--KIAVKRMESSVVSDKGLTEFKSEITVLTKMRHRHLVA 645 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQLLLFAQQICEGMAYLH 1015 G C D E+ LV EY+P G+L +L R + + L A + G+ YLH Sbjct 646 LLGYCLDGNER--LLVYEYMPQGTLSQHLFHWKEEGRKPLDWTRRLAIALDVARGVEYLH 703 Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APE 1071 Q +IHRDL N+LL +D K+ DFGL + P+G R G F Y APE Sbjct 704 TLAHQSFIHRDLKPSNILLGDDMRAKVSDFGLVRLAPDGKYSIETRVAG---TFGYLAPE 760 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 + D++S GV L EL+T Sbjct 761 YAVTGRVTTKVDIFSLGVILMELIT 785 Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 63/249 (25%), Positives = 101/249 (41%), Gaps = 44/249 (18%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--RERGHVPMAW-- 710 F ++++++ H HL + G C+ G E ++V EY+ G L L +E G P+ W Sbjct 628 FKSEITVLTKMRHRHLVALLGYCLDGNERLLVYEYMPQGTLSQHLFHWKEEGRKPLDWTR 687 Query 711 KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--- 764 ++ +A +A + YL ++ +H ++ NILL G K+SD G+ Sbjct 688 RLAIALDVARGVEYLHTLAHQSFIHRDLKPSNILL-------GDDMRAKVSDFGLVRLAP 740 Query 765 -GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 G S E RV +LAPE G ++T +D + G L+E+ G L P + Sbjct 741 DGKYSIETRVAGTFGYLAPEYAVTG--RVTTKVDIFSLGVILMEL-ITGRKALDETQPED 797 Query 823 KEHFYQRQHRLPEP----------------------SCPQLATLTSQCLTYEPTQRPSFR 860 H R+ S ++ L C EP QRP Sbjct 798 SVHLVTWFRRVAASKDENAFKNAIDPNISLDDDTVASIEKVWELAGHCCAREPYQRPDMA 857 Query 861 TILRDLTRL 869 I+ L+ L Sbjct 858 HIVNVLSSL 866 >sp|O08679|MARK2_RAT Serine/threonine-protein kinase MARK2 OS=Rattus norvegicus OX=10116 GN=Mark2 PE=1 SV=1 Length=722 Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 76/232 (33%), Positives = 115/232 (50%), Gaps = 18/232 (8%) Query 870 QPHNLADVLTVNPDSPASD--PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 +P + +++L + ++D P + + R LK I G+G+F KV L + T G+ V Sbjct 27 KPSSKSNMLRGRNSATSADEQPHIGNYRLLKTI---GKGNFAKVKLARHILT----GKEV 79 Query 928 AVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 AVK + K +E+ I++ L H +I+K E EK+L LVMEY G + Sbjct 80 AVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIET--EKTLYLVMEYASGGEV 137 Query 987 RDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 DYL H + + +QI + Y H + +HRDL A N+LLD D +KI DFG + Sbjct 138 FDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFS 197 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096 G++ G P + APE + K+ DVWS GV LY L++ Sbjct 198 NEFTFGNKLDTF--CGSPP--YAAPELFQGKKYDGPEVDVWSLGVILYTLVS 245 Score = 40.8 bits (94), Expect = 0.089, Method: Compositional matrix adjust. Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 22/236 (9%) Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K++D + + + + +M ++H ++ + V +V EY G + Sbjct 79 VAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVF 138 Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 +L H M K A+ Q+ SA+ Y K +VH ++ N+LL Sbjct 139 DYLV---AHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLL-------DADMN 188 Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 IK++D G + +++ P+ APE G +D W G L + Sbjct 189 IKIADFGFS-NEFTFGNKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLV-S 245 Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 G P ++ E +E + ++R+P L + L P++R + I++D Sbjct 246 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKD 301 >sp|Q9LK43|TMK4_ARATH Receptor-like kinase TMK4 OS=Arabidopsis thaliana OX=3702 GN=TMK4 PE=1 SV=1 Length=928 Score = 94.7 bits (234), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 73/205 (36%), Positives = 103/205 (50%), Gaps = 21/205 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG G FG V Y + +DGT AVK ++ A G + S ++ EI +L + H H++ Sbjct 584 LGRGGFGVV--YAGE-LHDGT--KTAVKRMECAAMGNKGMSEFQAEIAVLTKVRHRHLVA 638 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYLH 1015 G C + E+ LV EY+P G+L +L S + Q + A + G+ YLH Sbjct 639 LLGYCVNGNER--LLVYEYMPQGNLGQHLFEWSELGYSPLTWKQRVSIALDVARGVEYLH 696 Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APE 1071 + Q +IHRDL N+LL +D K+ DFGL K P+G R G F Y APE Sbjct 697 SLAQQSFIHRDLKPSNILLGDDMRAKVADFGLVKNAPDGKYSVETRLAG---TFGYLAPE 753 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 + DV++FGV L E+LT Sbjct 754 YAATGRVTTKVDVYAFGVVLMEILT 778 Score = 68.2 bits (165), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 64/235 (27%), Positives = 101/235 (43%), Gaps = 42/235 (18%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR--ERGHVPMAWK- 711 F +++++V H HL + G CV G E ++V EY+ G L L E G+ P+ WK Sbjct 621 FQAEIAVLTKVRHRHLVALLGYCVNGNERLLVYEYMPQGNLGQHLFEWSELGYSPLTWKQ 680 Query 712 -MVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 + +A +A + YL + ++ +H ++ NILL G K++D G+ A Sbjct 681 RVSIALDVARGVEYLHSLAQQSFIHRDLKPSNILL-------GDDMRAKVADFGLVKNAP 733 Query 768 SREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + VE +LAPE G ++T +D + FG L+EI G L P E Sbjct 734 DGKYSVETRLAGTFGYLAPEYAATG--RVTTKVDVYAFGVVLMEI-LTGRKALDDSLPDE 790 Query 823 KEHFYQ-------RQHRLPEP-------------SCPQLATLTSQCLTYEPTQRP 857 + H + +P+ S ++A L C EP QRP Sbjct 791 RSHLVTWFRRILINKENIPKALDQTLEADEETMESIYRVAELAGHCTAREPQQRP 845 >sp|O64768|RAF24_ARATH RAF-like serine/threonine-protein kinase 24 OS=Arabidopsis thaliana OX=3702 GN=RAF24 PE=1 SV=1 Length=1257 Score = 95.1 bits (235), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 93/297 (31%), Positives = 135/297 (45%), Gaps = 40/297 (13%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-----GPQHR--SG 943 V L+++++LG G FG V Y GT VA+K +K C Q R S Sbjct 968 VIKNDDLEELKELGSGTFGTV----YHGKWRGTD--VAIKRIKRSCFIGRSSEQERLTSE 1021 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLL 1001 + E +IL L+H +++ + G +D +L V EY+ GSLR L RH + + L Sbjct 1022 FWHEAEILSKLHHPNVMAFYGVVKDGPGGTLATVTEYMVNGSLRHVLLSNRH-LDRRKRL 1080 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDR-LVKIGDFGLAKAVPEGHEYYRV 1057 + A GM YLH++ +H DL N+L+ D R + K+GDFGL+K V Sbjct 1081 IIAMDAAFGMEYLHSKSIVHFDLKCDNLLVNLKDPARPICKVGDFGLSKIKRNTLVTGGV 1140 Query 1058 REDGDSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 R G P W APE L K DV+SFG+ L+E+LT + P + I Sbjct 1141 R--GTLP--WMAPELLSGSSSKVSEKVDVFSFGIVLWEILTGEE-----PYANMHYGAII 1191 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 G ++ R P+ C E LM+ CW + RP F + L+T+ Sbjct 1192 GG---------IVNNTLRPTVPNYCDPEWRMLMEQCWAPDPFVRPAFPEIARRLRTM 1239 Score = 79.3 bits (194), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 84/331 (25%), Positives = 135/331 (41%), Gaps = 59/331 (18%) Query 564 MRGARASPRTLNLS------------QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 ++GA ++ TLN S + ++ +L LG GT VY G+ R Sbjct 937 IKGAESTDATLNAGVPLIDFMAADSGMRSLQVIKNDDLEELKELGSGTFGTVYHGKWR-- 994 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 G K + GR QE + F+ A ++S++ H ++ Sbjct 995 --GTDVAIKRIKRSCFI-GRSSEQER-------------LTSEFWHEAEILSKLHHPNVM 1038 Query 672 FVHGVCVRGPENIM--VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729 +GV GP + VTEY+ +G L L R H+ ++++A A + YL +K+ Sbjct 1039 AFYGVVKDGPGGTLATVTEYMVNGSLRHVLLSNR-HLDRRKRLIIAMDAAFGMEYLHSKS 1097 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECL 784 +VH ++ N+L+ L + P K+ D GL + R V +PW+APE L Sbjct 1098 IVHFDLKCDNLLV---NLKDPARPICKVGD--FGLSKIKRNTLVTGGVRGTLPWMAPELL 1152 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF---------YQRQHRLPE 835 G ++ +S +D + FG L EI L P H+ + +P Sbjct 1153 SGSSSKVSEKVDVFSFGIVLWEI-------LTGEEPYANMHYGAIIGGIVNNTLRPTVPN 1205 Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 P+ L QC +P RP+F I R L Sbjct 1206 YCDPEWRMLMEQCWAPDPFVRPAFPEIARRL 1236 >sp|Q54WS5|ROCO6_DICDI Probable serine/threonine-protein kinase roco6 OS=Dictyostelium discoideum OX=44689 GN=roco6 PE=3 SV=1 Length=2147 Score = 95.1 bits (235), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 85/292 (29%), Positives = 139/292 (48%), Gaps = 49/292 (17%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--DCGPQHRSGWKQEIDILRTLYHEHII 960 +G G GK+ + T MVAVK L+ + P+ S +++EI ++ L H +++ Sbjct 1362 IGRGASGKIYRANLNDT------MVAVKQLEVVGEDAPRIFSEFRREIHVMSDLKHSNVV 1415 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IG------LAQLLLFAQQICEGMAY 1013 G +VMEY+ G L +L HS IG A +L A I +GM + Sbjct 1416 NLLGFTL----SPFTMVMEYIDCGDLHKFL--HSPIGDQLNGNWALILKLALDIAKGMEF 1469 Query 1014 LHAQH--YIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 LH+ +HRDL + NVLL D K+GDFGL+ + +++R + W Sbjct 1470 LHSVTPPLLHRDLKSPNVLLSMKDGVYTAKVGDFGLSSRMFIQALKHKLRNFPVGNITWV 1529 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 APE L+E ++ SDV++FG+ L+ELLT + P +F +++ L E Sbjct 1530 APEILREEEYTVKSDVYAFGLILHELLTR----KHPYREF---------NYSMVSLQE-- 1574 Query 1129 ERGERLPRPDKCPC--------EVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + + RP P E L+++CW+++ RPTF ++ +K + Sbjct 1575 DAIKNGLRPTISPSYTQTVTGHEYCGLIQDCWDSDIDRRPTFNKIVKRIKQI 1626 >sp|Q9V422|RYK2_DROME Tyrosine-protein kinase Dnt OS=Drosophila melanogaster OX=7227 GN=dnt PE=2 SV=2 Length=584 Score = 94.0 bits (232), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 71/267 (27%), Positives = 120/267 (45%), Gaps = 24/267 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 L EG FG+V Y+ T D V VK + QE +L H I+ Sbjct 323 LQEGTFGRVYRGTYNDTQD-----VLVKTVAQHASQMQVLLLLQEGMLLYGASHPGILSV 377 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 G + L +L+ +L ++ Q+++ A Q+ + +LH+ Sbjct 378 LGVSIEDHTTPFVLYPALNNTRNLKQFLLDPACARTVTTIQIVMMASQLSMALDHLHSHG 437 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +H+D+A RN ++D+ VK+ D L++ + +Y + + + PV W + E L+ +F Sbjct 438 VVHKDIATRNCVIDDQLRVKLSDSSLSRDLFPS-DYNCLGDSENRPVKWMSLEALQHKQF 496 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 ASD W+FGV ++EL C S++ P ++ + L+ G RL +P Sbjct 497 SEASDSWAFGVLMWEL---CTSAKQP-----------YAEVDPFEMEHYLKDGYRLAQPF 542 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENL 1165 CP E++ +M CW + RPTF L Sbjct 543 NCPDELFTIMAYCWALLPAERPTFAQL 569 Score = 64.3 bits (155), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 44/157 (28%), Positives = 73/157 (46%), Gaps = 19/157 (12%) Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-------L 764 +++A QL+ AL +L + +VH ++ RN ++ +KLSD + Sbjct 420 VMMASQLSMALDHLHSHGVVHKDIATRNCVI-------DDQLRVKLSDSSLSRDLFPSDY 472 Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 L E + W++ E L S A D W FG + E+C + P P E E Sbjct 473 NCLGDSEN-RPVKWMSLEALQH--KQFSEASDSWAFGVLMWELCTSAKQPYAEVDPFEME 529 Query 825 HFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSF 859 H+ + +RL +P +CP +L T+ + C P +RP+F Sbjct 530 HYLKDGYRLAQPFNCPDELFTIMAYCWALLPAERPTF 566 >sp|Q32MK0|MYLK3_HUMAN Myosin light chain kinase 3 OS=Homo sapiens OX=9606 GN=MYLK3 PE=1 SV=3 Length=819 Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 72/202 (36%), Positives = 101/202 (50%), Gaps = 23/202 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG+V + T TG +A K +K + R K EI+I+ L H ++I+ Sbjct 521 LGGGRFGQV----HRCTEKSTGLPLAAKIIKVKSA-KDREDVKNEINIMNQLSHVNLIQL 575 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020 E + S LVMEYV G L D + L +L +LF +QICEG+ YLH + + Sbjct 576 YDAFESK--HSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYIL 633 Query 1021 HRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVRE----DGDSPVFWYAPECLK 1074 H DL N+L N +KI DFGLA+ Y+ RE + +P F APE + Sbjct 634 HLDLKPENILCVNQTGHQIKIIDFGLAR-------RYKPREKLKVNFGTPEF-LAPEVVN 685 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + +D+WS GV Y LL+ Sbjct 686 YEFVSFPTDMWSVGVITYMLLS 707 >sp|Q6Z8C8|CDKF4_ORYSJ Cyclin-dependent kinase F-4 OS=Oryza sativa subsp. japonica OX=39947 GN=CDKF-4 PE=2 SV=1 Length=459 Score = 92.8 bits (229), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 67/206 (33%), Positives = 101/206 (49%), Gaps = 21/206 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 K I+++G+G FG V + N GE+VAVK +K +E+ LR + H Sbjct 4 FKMIKEVGDGTFGSV----WRAINKQNGEVVAVKKMKRKYYSFEECMSLREVKSLRRMNH 59 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLH 1015 +I+K K + L +MEY+ + R A++ + QI + +AY+H Sbjct 60 PNIVKLKEVIREND--ILYFIMEYMECNLYQLMKDRVKPFSEAEVRNWCFQIFQALAYMH 117 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAK---AVPEGHEYYRVREDGDSPVFWY-APE 1071 + Y HRDL N+L+ D ++K+ DFGLA+ +VP EY R WY APE Sbjct 118 QRGYFHRDLKPENLLVSKD-VIKLADFGLAREVTSVPPYTEYVSTR--------WYRAPE 168 Query 1072 CLKEYKFY-YASDVWSFGVTLYELLT 1096 L + Y A D+W+ G + ELLT Sbjct 169 VLLQSSIYDSAVDMWAMGAIMAELLT 194 >sp|Q7L7X3|TAOK1_HUMAN Serine/threonine-protein kinase TAO1 OS=Homo sapiens OX=9606 GN=TAOK1 PE=1 SV=1 Length=1001 Score = 94.7 bits (234), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 78/239 (33%), Positives = 115/239 (48%), Gaps = 32/239 (13%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956 +R++G G FG V Y + T E+VA+K + + G Q W+ +E+ L+ + H Sbjct 31 LREIGHGSFGAV----YFARDVRTNEVVAIKKM-SYSGKQSTEKWQDIIKEVKFLQRIKH 85 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014 + I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL Sbjct 86 PNSIEYKGCY--LREHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQGLAYL 142 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071 H+ IHRD+ A N+LL VK+ DFG A + + +P +W APE Sbjct 143 HSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFV------GTP-YWMAPEVIL 195 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP----TKFLELIGIAQGQMTVLRLTE 1126 + E ++ DVWS G+T EL + + PP L IAQ + L+ E Sbjct 196 AMDEGQYDGKVDVWSLGITCIEL-----AERKPPLFNMNAMSALYHIAQNESPTLQSNE 249 Score = 34.7 bits (78), Expect = 7.0, Method: Compositional matrix adjust. Identities = 25/89 (28%), Positives = 37/89 (42%), Gaps = 8/89 (9%) Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780 L+YL + ++H ++ NILL G +KL+D G A V W+A Sbjct 138 GLAYLHSHTMIHRDIKAGNILLTEPGQ-------VKLADFGSASMASPANSFVGTPYWMA 190 Query 781 PEC-LPGGANSLSTAMDKWGFGATLLEIC 808 PE L +D W G T +E+ Sbjct 191 PEVILAMDEGQYDGKVDVWSLGITCIELA 219 >sp|Q00526|CDK3_HUMAN Cyclin-dependent kinase 3 OS=Homo sapiens OX=9606 GN=CDK3 PE=1 SV=1 Length=305 Score = 90.5 bits (223), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 64/205 (31%), Positives = 104/205 (51%), Gaps = 15/205 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955 +K+ +GEG +G V Y N TG++VA+K ++ D + S +EI +L+ L Sbjct 4 FQKVEKIGEGTYGVV----YKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELK 59 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013 H +I++ + E+ L LV E++ L D P + L + + Q+ +G+++ Sbjct 60 HPNIVRLLDVVHN--ERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSF 117 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072 H+ IHRDL +N+L++ +K+ DFGLA+A Y + WY APE Sbjct 118 CHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTY----THEVVTLWYRAPEI 173 Query 1073 LKEYKFY-YASDVWSFGVTLYELLT 1096 L KFY A D+WS G E++T Sbjct 174 LLGSKFYTTAVDIWSIGCIFAEMVT 198 Score = 38.1 bits (87), Expect = 0.44, Method: Compositional matrix adjust. Identities = 58/268 (22%), Positives = 106/268 (40%), Gaps = 43/268 (16%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 R+ GQ + + LD + SL+ ++ H ++ + V + +V E+ Sbjct 23 NRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEF 82 Query 690 VEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + L ++ G +P+ QL +S+ + ++H ++ +N+L+ LG Sbjct 83 LSQD-LKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGA- 140 Query 749 EGTSPFIKLSDPGV----GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 IKL+D G+ G+ + V + + APE L G+ +TA+D W G Sbjct 141 ------IKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILL-GSKFYTTAVDIWSIGCIF 193 Query 805 LEIC-----FDGEA--------------------PLQSRSPSEKEHFYQRQHRLPEPSCP 839 E+ F G++ P ++ P K F + + E P Sbjct 194 AEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWTRKGLEEIVP 253 Query 840 QLA----TLTSQCLTYEPTQRPSFRTIL 863 L L Q L Y+P+QR + +T L Sbjct 254 NLEPEGRDLLMQLLQYDPSQRITAKTAL 281 >sp|Q8BYC6|TAOK3_MOUSE Serine/threonine-protein kinase TAO3 OS=Mus musculus OX=10090 GN=Taok3 PE=1 SV=2 Length=898 Score = 94.7 bits (234), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 72/203 (35%), Positives = 102/203 (50%), Gaps = 23/203 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956 + ++G G FG V Y TN T E+VAVK + + G Q W+ +E+ L+ L H Sbjct 27 LHEIGHGSFGAV----YFATNAHTNEVVAVKKM-SYSGKQTHEKWQDILKEVKFLQQLKH 81 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014 + I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL Sbjct 82 PNTIEYKGCY--LKEHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQGLAYL 138 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071 H IHRD+ A N+LL VK+ DFG A + + +P +W APE Sbjct 139 HFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFV------GTP-YWMAPEVIL 191 Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094 + E ++ D+WS G+T EL Sbjct 192 AMDEGQYDGKVDIWSLGITCIEL 214 >sp|Q802A6|STK4_SQUAC Serine/threonine-protein kinase 3/4 OS=Squalus acanthias OX=7797 GN=STK4 PE=2 SV=1 Length=491 Score = 93.2 bits (230), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 64/229 (28%), Positives = 108/229 (47%), Gaps = 18/229 (8%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 R PH + ++ DS P + + LGEG +G V + + +G++V Sbjct 7 RQHPHPRRSLKKLSEDSLTKQP----EEVFDVLEKLGEGSYGSV----FKAIHKESGQVV 58 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K + + Q +EI I++ H++KY G + L +VMEY GS+ Sbjct 59 AIKQVPVESDLQE---IIKEISIMQQCDSPHVVKYYGSYFKNTD--LWIVMEYCGAGSVS 113 Query 988 DYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 D + + L + + Q +G+ YLH IHRD+ A N+LL+N+ K+ DFG+A Sbjct 114 DLIRIRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNNEGHAKLADFGVA 173 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 + + R FW APE ++E + +D+WS G++ E+ Sbjct 174 GQLTDT---MAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGISAIEM 219 Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 51/214 (24%), Positives = 81/214 (38%), Gaps = 20/214 (9%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q H+ +G + + +V EY G + +R + + Q Sbjct 77 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDLIRIRNKTLTEDEIATILQSTL 136 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL +H ++ NILL G A KL+D GV +++ V Sbjct 137 KGLEYLHFMRKIHRDIKAGNILLNNEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 189 Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830 P W+APE + G N ++ D W G + +E+ +G+ P P Sbjct 190 PFWMAPEVIQEIGYNCVA---DIWSLGISAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 245 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R PE + QCL P QR + +L+ Sbjct 246 FRKPELWTDEFTDFVKQCLVKNPEQRAAATQLLQ 279 >sp|Q91ZR4|NEK8_MOUSE Serine/threonine-protein kinase Nek8 OS=Mus musculus OX=10090 GN=Nek8 PE=1 SV=1 Length=698 Score = 94.0 bits (232), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 64/203 (32%), Positives = 108/203 (53%), Gaps = 17/203 (8%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYH 956 ++IR +G G FG V L C + ++V +K + + + R + E +L+ L H Sbjct 5 ERIRVVGRGAFGIVHL-CLRKADQ---KLVILKQIPVEQMTKEERQAAQNECQVLKLLNH 60 Query 957 EHIIKY-KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMA 1012 ++I+Y + ED K+L + MEY P G+L +++ + L + +L F QI + Sbjct 61 PNVIEYYENFLED---KALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALH 117 Query 1013 YLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 ++H +HRDL +N+LLD R+ VKIGDFG++K + + Y V +P + +PE Sbjct 118 HVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVV---GTPCY-ISPE 173 Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094 + + SD+W+ G LYEL Sbjct 174 LCEGKPYNQKSDIWALGCVLYEL 196 >sp|B7ZR30|STK10_XENLA Serine/threonine-protein kinase 10-A OS=Xenopus laevis OX=8355 GN=stk10-a PE=1 SV=1 Length=950 Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 68/203 (33%), Positives = 106/203 (52%), Gaps = 19/203 (9%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I +LG+G FGKV Y N TG + A K ++ + + EI+IL T H I Sbjct 39 IGELGDGAFGKV----YKAKNRETGILAAAKVIETK-NEEELEDYMVEIEILATCNHHFI 93 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQ 1017 +K G +G+ L +++E+ P G++ + GL + + +Q+ E +AYLH+ Sbjct 94 VKLLGAFYWEGK--LWIMIEFCPGGAVDAVMLELDRGLKEPEIKTICRQMLEALAYLHSM 151 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVFWYAPEC---- 1072 IHRDL A NVLL D +K+ DFG+ AK V + + R+ +W APE Sbjct 152 KIIHRDLKAGNVLLTLDGDIKLADFGVSAKNV----KTLQRRDSFIGTPYWMAPEVVMCE 207 Query 1073 -LKEYKFYYASDVWSFGVTLYEL 1094 +K+ + Y +D+WS G+TL E+ Sbjct 208 TMKDAPYDYKADIWSLGITLIEM 230 Score = 40.8 bits (94), Expect = 0.096, Method: Compositional matrix adjust. Identities = 40/133 (30%), Positives = 60/133 (45%), Gaps = 17/133 (13%) Query 684 IMVTEYVEHGPLD-VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 IM+ E+ G +D V L +RG K + +Q+ AL+YL + ++H ++ N+LL Sbjct 108 IMI-EFCPGGAVDAVMLELDRGLKEPEIK-TICRQMLEALAYLHSMKIIHRDLKAGNVLL 165 Query 743 ARLGLAEGTSPFIKLSDPGV---GLGALSREERVERIP-WLAPE---CLPGGANSLSTAM 795 G IKL+D GV + L R + P W+APE C Sbjct 166 TLDG-------DIKLADFGVSAKNVKTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKA 218 Query 796 DKWGFGATLLEIC 808 D W G TL+E+ Sbjct 219 DIWSLGITLIEMA 231 >sp|P24941|CDK2_HUMAN Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2 Length=298 Score = 90.1 bits (222), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 65/205 (32%), Positives = 102/205 (50%), Gaps = 15/205 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955 +K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ L Sbjct 4 FQKVEKIGEGTYGVV----YKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYV--PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013 H +I+K E L LV E++ L D I L + + Q+ +G+A+ Sbjct 60 HPNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAF 117 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072 H+ +HRDL +N+L++ + +K+ DFGLA+A Y + WY APE Sbjct 118 CHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTY----THEVVTLWYRAPEI 173 Query 1073 LKEYKFY-YASDVWSFGVTLYELLT 1096 L K+Y A D+WS G E++T Sbjct 174 LLGCKYYSTAVDIWSLGCIFAEMVT 198 Score = 35.8 bits (81), Expect = 2.2, Method: Compositional matrix adjust. Identities = 65/321 (20%), Positives = 122/321 (38%), Gaps = 70/321 (22%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-LDPSHH 649 ++ +G+GT VY+ R ++ G E+ + K+ LD Sbjct 6 KVEKIGEGTYGVVYKARNKLTG-----------------------EVVALKKIRLDTETE 42 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 + SL+ +++H ++ + V + +V E++ +P+ Sbjct 43 GVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLP 102 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLG 765 QL L++ + ++H ++ +N+L+ T IKL+D G+ G+ Sbjct 103 LIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI-------NTEGAIKLADFGLARAFGVP 155 Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQS--- 817 + V + + APE L G STA+D W G E+ F G++ + Sbjct 156 VRTYTHEVVTLWYRAPEIL-LGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFR 214 Query 818 ---RSPSEKEHFYQRQHRLPE--PSCPQLA----------------TLTSQCLTYEPTQR 856 + E + +P+ PS P+ A +L SQ L Y+P +R Sbjct 215 IFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKR 274 Query 857 PSFRTIL-----RDLTRLQPH 872 S + L +D+T+ PH Sbjct 275 ISAKAALAHPFFQDVTKPVPH 295 >sp|Q03141|MARK3_MOUSE MAP/microtubule affinity-regulating kinase 3 OS=Mus musculus OX=10090 GN=Mark3 PE=1 SV=2 Length=753 Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 72/211 (34%), Positives = 103/211 (49%), Gaps = 16/211 (8%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQE 947 P + + R LK I G+G+F KV L + T G VA+K + K P +E Sbjct 51 PHIGNYRLLKTI---GKGNFAKVKLARHILT----GREVAIKIIDKTQLNPTSLQKLFRE 103 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQ 1006 + I++ L H +I+K E EK+L L+MEY G + DYL H + + +Q Sbjct 104 VRIMKILNHPNIVKLFEVIET--EKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 161 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I + Y H + +HRDL A N+LLD D +KI DFG + G + G P Sbjct 162 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGSKLDTF--CGSPP-- 217 Query 1067 WYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096 + APE + K+ DVWS GV LY L++ Sbjct 218 YAAPELFQGKKYDGPEVDVWSLGVILYTLVS 248 Score = 40.8 bits (94), Expect = 0.095, Method: Compositional matrix adjust. Identities = 49/236 (21%), Positives = 93/236 (39%), Gaps = 22/236 (9%) Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K++D + + + +M ++H ++ + V ++ EY G + Sbjct 82 VAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVF 141 Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 +L H M K A+ Q+ SA+ Y K +VH ++ N+LL Sbjct 142 DYLV---AHGRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLL-------DADMN 191 Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 IK++D G + +++ P+ APE G +D W G L + Sbjct 192 IKIADFGFS-NEFTVGSKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLV-S 248 Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 G P ++ E +E + ++R+P L + L P +R + I++D Sbjct 249 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMKD 304 >sp|Q95KV0|IKKB_BOVIN Inhibitor of nuclear factor kappa-B kinase subunit beta OS=Bos taurus OX=9913 GN=IKBKB PE=2 SV=1 Length=756 Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 69/207 (33%), Positives = 100/207 (48%), Gaps = 23/207 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + N TGE +A+K + + P++R W EI I+R L H +++ Sbjct 21 LGTGGFGNVIRW----HNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLNHPNVVAA 76 Query 963 KGCCEDQGEKSLQ------LVMEYVPLGSLRDYLPR--HSIGLAQ--LLLFAQQICEGMA 1012 + E G +SL L MEY G LR YL + + GL + +L I + Sbjct 77 RDVPE--GMQSLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALR 134 Query 1013 YLHAQHYIHRDLAARNVLLDN--DRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH IHRDL N++L RL+ KI D G AK + +G + + + A Sbjct 135 YLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGS----LCTSFVGTLQYLA 190 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096 PE L++ K+ D WSFG +E +T Sbjct 191 PELLEQQKYTVTVDYWSFGTLAFECIT 217 >sp|Q9HFW2|CLA4_EREGS Serine/threonine-protein kinase CLA4 OS=Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=CLA4 PE=3 SV=1 Length=793 Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 69/232 (30%), Positives = 108/232 (47%), Gaps = 33/232 (14%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLY------CYDPT--------NDGTGEMVAVKAL 932 +DP+ F + I G+G G V L YD ND G+ VA+K + Sbjct 492 TDPSPF----FQMIEKAGQGASGSVYLAQRLKIPPYDENSGVSQHELNDNIGDKVAIKQM 547 Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992 P+ + EI +++ H++I+ + + E L +VMEY+ GSL D + Sbjct 548 ILSKQPR-KELIVNEILVMKDSQHKNIVNFLEAYL-KTEDDLWVVMEYMEGGSLTDVI-E 604 Query 993 HSIGL---------AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 +SIG Q+ ++ C+G+ +LH +H IHRD+ + NVLLD VKI DFG Sbjct 605 NSIGSDASESPMTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTHGRVKITDFG 664 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 + + R +W APE +K+ ++ DVWS G+ E+L Sbjct 665 FCAKLTDKRSK---RATMVGTPYWMAPEVVKQREYDEKVDVWSLGIMTIEML 713 Score = 39.7 bits (91), Expect = 0.20, Method: Compositional matrix adjust. Identities = 51/214 (24%), Positives = 89/214 (42%), Gaps = 33/214 (15%) Query 685 MVTEYVEHGPLDVWLRRERG----HVPMAWKMV--VAQQLASALSYLENKNLVHGNVCGR 738 +V EY+E G L + G PM + + ++ L +L +K+++H ++ Sbjct 589 VVMEYMEGGSLTDVIENSIGSDASESPMTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSD 648 Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLS 792 N+LL G +K++D G A ++R +R W+APE + Sbjct 649 NVLLDTHGR-------VKITD--FGFCAKLTDKRSKRATMVGTPYWMAPEVV--KQREYD 697 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLT-----SQ 847 +D W G +E+ +GE P + P K + + P+ P+L +L S Sbjct 698 EKVDVWSLGIMTIEM-LEGEPPYLNEEPL-KALYLIATNGTPKLKHPELLSLEIKRFLSV 755 Query 848 CLTYEPTQRPSFRTILRDL---TRLQPHNLADVL 878 CL + R S +L T +P LA++L Sbjct 756 CLCVDVRYRASTEELLHHSFFETSCEPEELANLL 789 >sp|O88664|TAOK1_RAT Serine/threonine-protein kinase TAO1 OS=Rattus norvegicus OX=10116 GN=Taok1 PE=1 SV=1 Length=1001 Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 78/239 (33%), Positives = 115/239 (48%), Gaps = 32/239 (13%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956 +R++G G FG V Y + T E+VA+K + + G Q W+ +E+ L+ + H Sbjct 31 LREIGHGSFGAV----YFARDVRTNEVVAIKKM-SYSGKQSTEKWQDIIKEVKFLQRIKH 85 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014 + I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL Sbjct 86 PNSIEYKGCY--LREHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQGLAYL 142 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071 H+ IHRD+ A N+LL VK+ DFG A + + +P +W APE Sbjct 143 HSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFV------GTP-YWMAPEVIL 195 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP----TKFLELIGIAQGQMTVLRLTE 1126 + E ++ DVWS G+T EL + + PP L IAQ + L+ E Sbjct 196 AMDEGQYDGKVDVWSLGITCIEL-----AERKPPLFNMNAMSALYHIAQNESPTLQSNE 249 Score = 34.7 bits (78), Expect = 7.6, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 8/88 (9%) Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781 L+YL + ++H ++ NILL G +KL+D G A V W+AP Sbjct 139 LAYLHSHTMIHRDIKAGNILLTEPGQ-------VKLADFGSASMASPANSFVGTPYWMAP 191 Query 782 EC-LPGGANSLSTAMDKWGFGATLLEIC 808 E L +D W G T +E+ Sbjct 192 EVILAMDEGQYDGKVDVWSLGITCIELA 219 >sp|Q38997|KIN10_ARATH SNF1-related protein kinase catalytic subunit alpha KIN10 OS=Arabidopsis thaliana OX=3702 GN=KIN10 PE=1 SV=3 Length=512 Score = 93.2 bits (230), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 74/200 (37%), Positives = 100/200 (50%), Gaps = 16/200 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEH 958 R LG G FG+V + + TG VA+K L + + ++EI ILR H H Sbjct 23 RTLGIGSFGRVKI----AEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPH 78 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 II+ E + + LVMEYV G L DY+ + + + F QQI G+ Y H Sbjct 79 IIRLYEVIETPTD--IYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRN 136 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL N+LLD+ VKI DFGL+ + +GH ++ SP + APE + K Sbjct 137 MVVHRDLKPENLLLDSKCNVKIADFGLSNIMRDGH---FLKTSCGSPNY-AAPEVISG-K 191 Query 1078 FYYA--SDVWSFGVTLYELL 1095 Y DVWS GV LY LL Sbjct 192 LYAGPEVDVWSCGVILYALL 211 Score = 34.3 bits (77), Expect = 8.7, Method: Compositional matrix adjust. Identities = 57/263 (22%), Positives = 99/263 (38%), Gaps = 20/263 (8%) Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726 H H+ ++ V + +V EYV G L ++ E+G + QQ+ S + Y Sbjct 76 HPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIV-EKGRLQEDEARNFFQQIISGVEYCH 134 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-----WLAP 781 +VH ++ N+LL + +K++D GL + R+ + + AP Sbjct 135 RNMVVHRDLKPENLLL-------DSKCNVKIAD--FGLSNIMRDGHFLKTSCGSPNYAAP 185 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQ 840 E + G + +D W G L + G P + P+ + + LP P Sbjct 186 EVISGKLYA-GPEVDVWSCGVILYALLC-GTLPFDDENIPNLFKKIKGGIYTLPSHLSPG 243 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 L + L +P +R + I R Q H L L V P + L+++ Sbjct 244 ARDLIPRMLVVDPMKRVTIPEI-RQHPWFQAH-LPRYLAVPPPDTVQQAKKIDEEILQEV 301 Query 901 RDLGEGHFGKVSLYCYDPTNDGT 923 ++G + NDGT Sbjct 302 INMGFDRNHLIESLRNRTQNDGT 324 >sp|Q5F2E8|TAOK1_MOUSE Serine/threonine-protein kinase TAO1 OS=Mus musculus OX=10090 GN=Taok1 PE=1 SV=1 Length=1001 Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 78/239 (33%), Positives = 115/239 (48%), Gaps = 32/239 (13%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956 +R++G G FG V Y + T E+VA+K + + G Q W+ +E+ L+ + H Sbjct 31 LREIGHGSFGAV----YFARDVRTNEVVAIKKM-SYSGKQSTEKWQDIIKEVKFLQRIKH 85 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014 + I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL Sbjct 86 PNSIEYKGCY--LREHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQGLAYL 142 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071 H+ IHRD+ A N+LL VK+ DFG A + + +P +W APE Sbjct 143 HSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFV------GTP-YWMAPEVIL 195 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP----TKFLELIGIAQGQMTVLRLTE 1126 + E ++ DVWS G+T EL + + PP L IAQ + L+ E Sbjct 196 AMDEGQYDGKVDVWSLGITCIEL-----AERKPPLFNMNAMSALYHIAQNESPTLQSNE 249 Score = 34.7 bits (78), Expect = 7.7, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 8/88 (9%) Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781 L+YL + ++H ++ NILL G +KL+D G A V W+AP Sbjct 139 LAYLHSHTMIHRDIKAGNILLTEPGQ-------VKLADFGSASMASPANSFVGTPYWMAP 191 Query 782 EC-LPGGANSLSTAMDKWGFGATLLEIC 808 E L +D W G T +E+ Sbjct 192 EVILAMDEGQYDGKVDVWSLGITCIELA 219 >sp|Q5RDG7|MYLK3_PONAB Myosin light chain kinase 3 OS=Pongo abelii OX=9601 GN=MYLK3 PE=2 SV=3 Length=819 Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 72/202 (36%), Positives = 101/202 (50%), Gaps = 23/202 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG+V + T TG +A K +K + R K EI+I+ L H ++I+ Sbjct 521 LGGGRFGQV----HRCTEKSTGLPLAAKIIKVKSA-KDREDVKNEINIMNQLSHVNLIQL 575 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020 E + S LVMEYV G L D + L +L +LF +QICEG+ YLH + + Sbjct 576 YDAFESK--HSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYIL 633 Query 1021 HRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVRE----DGDSPVFWYAPECLK 1074 H DL N+L N +KI DFGLA+ Y+ RE + +P F APE + Sbjct 634 HLDLKPENILCVNQTGHQIKIIDFGLAR-------RYKPREKLKVNFGTPEF-LAPEVVN 685 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + +D+WS GV Y LL+ Sbjct 686 YEFVSFPTDMWSVGVITYMLLS 707 Score = 34.3 bits (77), Expect = 9.7, Method: Compositional matrix adjust. Identities = 39/170 (23%), Positives = 72/170 (42%), Gaps = 11/170 (6%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 ++M+Q+SH +L ++ +V EYV+ G L + E+ H+ ++ +Q+ Sbjct 562 NIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQIC 621 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE---RVERI 776 + YL ++H ++ NIL T IK+ D G+ RE+ Sbjct 622 EGVHYLHQHYILHLDLKPENILCVNQ-----TGHQIKIIDFGLARRYKPREKLKVNFGTP 676 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 +LAPE + +S D W G + + G +P + +E +F Sbjct 677 EFLAPEVV--NYEFVSFPTDMWSVG-VITYMLLSGLSPFLGETDAETMNF 723 >sp|Q9FLJ8|Y5613_ARATH Probable receptor-like protein kinase At5g61350 OS=Arabidopsis thaliana OX=3702 GN=At5g61350 PE=2 SV=1 Length=842 Score = 94.4 bits (233), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 72/206 (35%), Positives = 101/206 (49%), Gaps = 26/206 (13%) Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963 G G FGKV Y DG G VA+K + Q + ++ EI +L L H H++ Sbjct 532 GVGGFGKV----YIGEIDG-GTQVAIKR-GSQSSEQGINEFQTEIQMLSKLRHRHLVSLI 585 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYL---------PRHSIGLAQLLLFAQQICEGMAYL 1014 G C++ K + LV EY+ G LRD+L P ++ Q L G+ YL Sbjct 586 GFCDEN--KEMILVYEYMSNGPLRDHLYGSKENDPNPIPTLSWKQRLEICIGSARGLHYL 643 Query 1015 H---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP--EGHEYYRVREDGDSPVFWYA 1069 H AQ IHRD+ N+LLD + + K+ DFGL+K P EGH V+ + Sbjct 644 HTGAAQGIIHRDVKTTNILLDENLVAKVSDFGLSKDAPMDEGHVSTAVK----GSFGYLD 699 Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095 PE + + SDV+SFGV L+E+L Sbjct 700 PEYFRRQQLTDKSDVYSFGVVLFEVL 725 Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust. Identities = 47/168 (28%), Positives = 72/168 (43%), Gaps = 24/168 (14%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP-----MA 709 F ++S++ H HL + G C E I+V EY+ +GPL L + + P ++ Sbjct 566 FQTEIQMLSKLRHRHLVSLIGFCDENKEMILVYEYMSNGPLRDHLYGSKENDPNPIPTLS 625 Query 710 WKMVVAQQLASA--LSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 WK + + SA L YL + ++H +V NILL +A K+SD G+ Sbjct 626 WKQRLEICIGSARGLHYLHTGAAQGIIHRDVKTTNILLDENLVA-------KVSDFGLSK 678 Query 765 GALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 A E V +L PE L+ D + FG L E+ Sbjct 679 DAPMDEGHVSTAVKGSFGYLDPEYFR--RQQLTDKSDVYSFGVVLFEV 724 >sp|Q94CG0|CIPKL_ARATH CBL-interacting serine/threonine-protein kinase 21 OS=Arabidopsis thaliana OX=3702 GN=CIPK21 PE=1 SV=1 Length=416 Score = 92.0 bits (227), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 74/199 (37%), Positives = 106/199 (53%), Gaps = 15/199 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEH 958 R +GEG+F KV L YD TN G VAVK + Q S K+EI ++ L H + Sbjct 16 RTIGEGNFAKVKL-GYDTTN---GTYVAVKIIDKALVIQKGLESQVKREIRTMKLLNHPN 71 Query 959 IIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 I++ E G K+ + +VMEYV G L D L R + + QQ+ + + Y H + Sbjct 72 IVQIH---EVIGTKTKICIVMEYVSGGQLSDRLGRQKMKESDARKLFQQLIDAVDYCHNR 128 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 HRDL +N+LLD+ +K+ DFGL+ AVP+ + + SP + APE + Sbjct 129 GVYHRDLKPQNLLLDSKGNLKVSDFGLS-AVPKSGDM--LSTACGSPC-YIAPELIMNKG 184 Query 1078 FYYAS-DVWSFGVTLYELL 1095 + A+ DVWS GV L+ELL Sbjct 185 YSGAAVDVWSCGVILFELL 203 Score = 43.5 bits (101), Expect = 0.011, Method: Compositional matrix adjust. Identities = 41/151 (27%), Positives = 68/151 (45%), Gaps = 17/151 (11%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA 721 M ++H ++ +H V + +V EYV G L L R++ A K+ QQL A Sbjct 64 MKLLNHPNIVQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQKMKESDARKLF--QQLIDA 121 Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---- 777 + Y N+ + H ++ +N+LL G +K+SD GL A+ + + Sbjct 122 VDYCHNRGVYHRDLKPQNLLLDSKG-------NLKVSD--FGLSAVPKSGDMLSTACGSP 172 Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 ++APE + S A+D W G L E+ Sbjct 173 CYIAPELIMNKGYS-GAAVDVWSCGVILFEL 202 >sp|O88351|IKKB_MOUSE Inhibitor of nuclear factor kappa-B kinase subunit beta OS=Mus musculus OX=10090 GN=Ikbkb PE=1 SV=1 Length=757 Score = 94.0 bits (232), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 68/207 (33%), Positives = 101/207 (49%), Gaps = 23/207 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + N TGE +A+K + + P++R+ W EI I+R L H +++ Sbjct 21 LGTGGFGNVIRW----HNQATGEQIAIKQCRQELSPKNRNRWCLEIQIMRRLNHPNVVAA 76 Query 963 KGCCEDQGEKSLQ------LVMEYVPLGSLRDYLPR--HSIGLAQ--LLLFAQQICEGMA 1012 + E G ++L L MEY G LR YL + + GL + +L I + Sbjct 77 RDVPE--GMQNLAPNDLPLLAMEYCQGGDLRRYLNQFENCCGLREGAVLTLLSDIASALR 134 Query 1013 YLHAQHYIHRDLAARNVLLDN--DRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH IHRDL N++L RL+ KI D G AK + +G + + + A Sbjct 135 YLHENRIIHRDLKPENIVLQQGEKRLIHKIIDLGYAKELDQGS----LCTSFVGTLQYLA 190 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096 PE L++ K+ D WSFG +E +T Sbjct 191 PELLEQQKYTVTVDYWSFGTLAFECIT 217 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 Length=788 Score = 94.0 bits (232), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 73/211 (35%), Positives = 104/211 (49%), Gaps = 16/211 (8%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQE 947 P + + R LK I G+G+F KV L + T G+ VAVK + K +E Sbjct 48 PHIGNYRLLKTI---GKGNFAKVKLARHILT----GKEVAVKIIDKTQLNSSSLQKLFRE 100 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQ 1006 + I++ L H +I+K E EK+L LVMEY G + DYL H + + +Q Sbjct 101 VRIMKVLNHPNIVKLFEVIET--EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 158 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I + Y H + +HRDL A N+LLD D +KI DFG + G++ G P Sbjct 159 IVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTF--CGSPP-- 214 Query 1067 WYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096 + APE + K+ DVWS GV LY L++ Sbjct 215 YAAPELFQGKKYDGPEVDVWSLGVILYTLVS 245 Score = 40.4 bits (93), Expect = 0.13, Method: Compositional matrix adjust. Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 22/236 (9%) Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K++D + + + + +M ++H ++ + V +V EY G + Sbjct 79 VAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVF 138 Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 +L H M K A+ Q+ SA+ Y K +VH ++ N+LL Sbjct 139 DYLV---AHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLL-------DADMN 188 Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 IK++D G + +++ P+ APE G +D W G L + Sbjct 189 IKIADFGFS-NEFTFGNKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLV-S 245 Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 G P ++ E +E + ++R+P L + L P++R + I++D Sbjct 246 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKD 301 >sp|Q6NKZ9|Y4345_ARATH Probable receptor-like serine/threonine-protein kinase At4g34500 OS=Arabidopsis thaliana OX=3702 GN=At4g34500 PE=2 SV=1 Length=437 Score = 92.4 bits (228), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 78/278 (28%), Positives = 127/278 (46%), Gaps = 19/278 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG +G V Y D ++ G + AVK L + G Q +K E++ + + H++++ Sbjct 151 IGEGGYGVV--YRADFSD---GSVAAVKNLLNNKG-QAEKEFKVEVEAIGKVRHKNLVGL 204 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 G C D + LV EY+ G+L +L P + + A +G+AYLH Sbjct 205 MGYCADSAQSQRMLVYEYIDNGNLEQWLHGDVGPVSPLTWDIRMKIAIGTAKGLAYLHEG 264 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECL 1073 +HRD+ + N+LLD K+ DFGLAK + Y R G F Y +PE Sbjct 265 LEPKVVHRDVKSSNILLDKKWNAKVSDFGLAKLLGSETSYVTTRVMG---TFGYVSPEYA 321 Query 1074 KEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 SDV+SFGV L E++T S P + L+ +G + R E+++ Sbjct 322 STGMLNECSDVYSFGVLLMEIITGRSPVDYSRPPGEMNLVDWFKGMVASRRGEEVIDPKI 381 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + P + + C + ++S RP +I +L+ Sbjct 382 KTSPPPRALKRALLVCLRCIDLDSSKRPKMGQIIHMLE 419 Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 63/233 (27%), Positives = 104/233 (45%), Gaps = 41/233 (18%) Query 662 MSQVSHTHLAFVHGVCVRGPEN--IMVTEYVEHGPLDVWLRRERGHV-PMAW--KMVVAQ 716 + +V H +L + G C ++ ++V EY+++G L+ WL + G V P+ W +M +A Sbjct 193 IGKVRHKNLVGLMGYCADSAQSQRMLVYEYIDNGNLEQWLHGDVGPVSPLTWDIRMKIAI 252 Query 717 QLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSR-- 769 A L+YL +VH +V NILL + A K+SD G+ LG+ + Sbjct 253 GTAKGLAYLHEGLEPKVVHRDVKSSNILLDKKWNA-------KVSDFGLAKLLGSETSYV 305 Query 770 EERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ-SRSPSE----- 822 RV +++PE G L+ D + FG L+EI G +P+ SR P E Sbjct 306 TTRVMGTFGYVSPEYASTGM--LNECSDVYSFGVLLMEI-ITGRSPVDYSRPPGEMNLVD 362 Query 823 -----------KEHFYQRQHRLPEPSCPQLATLTS-QCLTYEPTQRPSFRTIL 863 +E + P P + A L +C+ + ++RP I+ Sbjct 363 WFKGMVASRRGEEVIDPKIKTSPPPRALKRALLVCLRCIDLDSSKRPKMGQII 415 >sp|P0C0K7|EPHB6_RAT Ephrin type-B receptor 6 OS=Rattus norvegicus OX=10116 GN=Ephb6 PE=3 SV=3 Length=1013 Score = 94.4 bits (233), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 73/290 (25%), Positives = 132/290 (46%), Gaps = 36/290 (12%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DPT Y+K +G G FG+V P + VA++AL A + + Sbjct 658 DPT-----YIKIEEVIGAGSFGEVRRGRLQPRGRRE-QAVAIQALWAGGAESLKMTFLGR 711 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ- 1006 +L H +I++ +G + + ++ E + LG L +L + + L L A Q Sbjct 712 AALLGQFQHPNILRLEGVVTR--SRPVMVLTELMELGPLDSFLRQREGQFSSLQLVAMQR 769 Query 1007 -ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 + M YL + ++HR L+AR+VL+++ + K+ G + P+G S + Sbjct 770 GVAAAMQYLSSFAFVHRALSARSVLVNSHLVCKVARLGHS---PQG---------SSSLL 817 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 W APE + K+ +SDVWSFG+ ++E++++ + M+ + Sbjct 818 RWAAPEVITHGKYTTSSDVWSFGILMWEVMSYGER--------------PYWDMSDQEVL 863 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 +E+ RLP P CP ++ LM + W+ + + RP F+ L+ + K Sbjct 864 NAIEQEFRLPPPPGCPTGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRK 913 Score = 74.7 bits (182), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 61/250 (24%), Positives = 109/250 (44%), Gaps = 34/250 (14%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 R R ++ + + + + F A+L+ Q H ++ + GV R +++TE + Sbjct 684 RGRREQAVAIQALWAGGAESLKMTFLGRAALLGQFQHPNILRLEGVVTRSRPVMVLTELM 743 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL--------L 742 E GPLD +LR+ G + + + +A+A+ YL + VH + R++L + Sbjct 744 ELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRALSARSVLVNSHLVCKV 803 Query 743 ARLGLA-EGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 ARLG + +G+S ++ W APE + G +T+ D W FG Sbjct 804 ARLGHSPQGSSSLLR---------------------WAAPEVITHG--KYTTSSDVWSFG 840 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSF 859 + E+ GE P S E + +++ RL P P CP L L + +RP F Sbjct 841 ILMWEVMSYGERPYWDMSDQEVLNAIEQEFRLPPPPGCPTGLHLLMLDTWQKDRARRPHF 900 Query 860 RTILRDLTRL 869 ++ ++ Sbjct 901 DQLVAAFDKM 910 >sp|Q3E8W4|ANX2_ARATH Receptor-like protein kinase ANXUR2 OS=Arabidopsis thaliana OX=3702 GN=ANX2 PE=1 SV=1 Length=858 Score = 94.0 bits (232), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 79/276 (29%), Positives = 129/276 (47%), Gaps = 26/276 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FGKV Y DG G VA+K + Q + ++ EI++L L H+H++ Sbjct 527 IGVGGFGKV----YKGVIDG-GTKVAIKKSNPNS-EQGLNEFETEIELLSRLRHKHLVSL 580 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA--- 1016 G C++ GE + L+ +Y+ LG+LR++L R + + L A G+ YLH Sbjct 581 IGYCDEGGE--MCLIYDYMSLGTLREHLYNTKRPQLTWKRRLEIAIGAARGLHYLHTGAK 638 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE---GHEYYRVREDGDSPVFWYAPECL 1073 IHRD+ N+LLD + + K+ DFGL+K P GH V+ + PE Sbjct 639 YTIIHRDVKTTNILLDENWVAKVSDFGLSKTGPNMNGGHVTTVVK----GSFGYLDPEYF 694 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR---LTELLER 1130 + + SDV+SFGV L+E+L C P+ E + + M R L ++++ Sbjct 695 RRQQLTEKSDVYSFGVVLFEVL--CARPALNPSLSKEQVSLGDWAMNCKRKGTLEDIIDP 752 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + +C + + C RPT +++ Sbjct 753 NLKGKINPECLKKFADTAEKCLSDSGLDRPTMGDVL 788 Score = 42.4 bits (98), Expect = 0.031, Method: Compositional matrix adjust. Identities = 42/175 (24%), Positives = 74/175 (42%), Gaps = 9/175 (5%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K +P+ F L+S++ H HL + G C G E ++ +Y+ G L Sbjct 545 KVAIKKSNPNSEQGLNEFETEIELLSRLRHKHLVSLIGYCDEGGEMCLIYDYMSLGTLRE 604 Query 698 WLRRERGHVPMAWK--MVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752 L + + WK + +A A L YL ++H +V NILL +A+ + Sbjct 605 HLYNTK-RPQLTWKRRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILLDENWVAKVSD 663 Query 753 PFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 + + P + G ++ + +L PE L+ D + FG L E+ Sbjct 664 FGLSKTGPNMNGGHVTTVVK-GSFGYLDPEYFR--RQQLTEKSDVYSFGVVLFEV 715 >sp|Q1PE89|PBL24_ARATH Probable serine/threonine-protein kinase PBL24 OS=Arabidopsis thaliana OX=3702 GN=PBL24 PE=2 SV=1 Length=389 Score = 91.7 bits (226), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 77/219 (35%), Positives = 110/219 (50%), Gaps = 21/219 (10%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 A+ F + +L +GEG FG+V Y + TG++VAVK L + G Q + Sbjct 65 ATATNSFRQEFL-----IGEGGFGRV----YKGKMEKTGQVVAVKQLDRN-GLQGNREFL 114 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL----- 1000 EI L L+H ++ G C D G++ L LV E++PLGSL D+L +G L Sbjct 115 VEIFRLSLLHHPNLANLIGYCLD-GDQRL-LVHEFMPLGSLEDHLLDVVVGQQPLDWNSR 172 Query 1001 LLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + A +G+ YLH + I+RD + N+LL+ D K+ DFGLAK G + V Sbjct 173 IRIALGAAKGLEYLHEKANPPVIYRDFKSSNILLNVDFDAKLSDFGLAKLGSVG-DTQNV 231 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 + APE K + SDV+SFGV L EL+T Sbjct 232 SSRVVGTYGYCAPEYHKTGQLTVKSDVYSFGVVLLELIT 270 Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 69/283 (24%), Positives = 111/283 (39%), Gaps = 43/283 (15%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DV 697 V +K LD + F +S + H +LA + G C+ G + ++V E++ G L D Sbjct 97 VAVKQLDRNGLQGNREFLVEIFRLSLLHHPNLANLIGYCLDGDQRLLVHEFMPLGSLEDH 156 Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTS 752 L G P+ W ++ +A A L YL K +++ + NILL Sbjct 157 LLDVVVGQQPLDWNSRIRIALGAAKGLEYLHEKANPPVIYRDFKSSNILL-------NVD 209 Query 753 PFIKLSDPGVG-LGALSREERVE-RIPWLAPECLPG--GANSLSTAMDKWGFGATLLEIC 808 KLSD G+ LG++ + V R+ C P L+ D + FG LLE+ Sbjct 210 FDAKLSDFGLAKLGSVGDTQNVSSRVVGTYGYCAPEYHKTGQLTVKSDVYSFGVVLLEL- 268 Query 809 FDGEAPLQSRSPSEKEHFYQ-------------------RQHRLPEPSCPQLATLTSQCL 849 G+ + + P +++ Q PE S Q + + CL Sbjct 269 ITGKRVIDTTRPCHEQNLVTWAQPIFREPNRFPELADPLLQGEFPEKSLNQAVAIAAMCL 328 Query 850 TYEPTQRPSFRTILRDLTRL-----QPHNLADVLTVNPDSPAS 887 EP RP ++ L+ + P L +NP SP + Sbjct 329 QEEPIVRPLISDVVTALSFMSTETGSPSGLTGT-ALNPLSPKT 370 >sp|B4KPU0|PTK7_DROMO Tyrosine-protein kinase-like otk OS=Drosophila mojavensis OX=7230 GN=otk PE=3 SV=1 Length=1045 Score = 94.4 bits (233), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 70/254 (28%), Positives = 120/254 (47%), Gaps = 30/254 (12%) Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 +V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY G Sbjct 795 LVMVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPH--YMVLEYTDWGD 852 Query 986 LRDYLPRHS--------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031 L+ +L + + +QLL A QI GM ++ + HRDLA RN ++ Sbjct 853 LKQFLLATAGKVNTATATSSPPPLTTSQLLAVAYQIARGMDAIYRARFTHRDLATRNCVI 912 Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091 ++ +VK+ L K EY++ R + PV W APEC++E ++ SD+++F V + Sbjct 913 SSEFIVKVAYPALCKD-KYSREYHKHR-NTLLPVRWLAPECIQEDEYTTKSDIFAFAVVV 970 Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 +EL TK L ++ Q+ L LE PD + ++ +C Sbjct 971 WELFNQA-------TK-LPHEDLSNEQVVQRSLANTLEWSVAEGTPDG----LKEILLSC 1018 Query 1152 WETEASFRPTFENL 1165 W T RP+F L Sbjct 1019 WLTNPKERPSFSQL 1032 Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 62/258 (24%), Positives = 103/258 (40%), Gaps = 37/258 (14%) Query 636 ELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 +L V++K L+ + A F L+ +SH + + G+C + MV EY + G Sbjct 793 DLLVMVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDWGD 852 Query 695 LDVWLRRERGHVPMAWK------------MVVAQQLASALSYLENKNLVHGNVCGRNILL 742 L +L G V A + VA Q+A + + H ++ RN ++ Sbjct 853 LKQFLLATAGKVNTATATSSPPPLTTSQLLAVAYQIARGMDAIYRARFTHRDLATRNCVI 912 Query 743 ARLGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMD 796 +S FI K++ P + SRE R + WLAPEC+ + +T D Sbjct 913 --------SSEFIVKVAYPALCKDKYSREYHKHRNTLLPVRWLAPECIQ--EDEYTTKSD 962 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR------QHRLPEPSCPQLATLTSQCLT 850 + F + E+ F+ L S E QR + + E + L + C Sbjct 963 IFAFAVVVWEL-FNQATKLPHEDLS-NEQVVQRSLANTLEWSVAEGTPDGLKEILLSCWL 1020 Query 851 YEPTQRPSFRTILRDLTR 868 P +RPSF + L++ Sbjct 1021 TNPKERPSFSQLGAALSK 1038 >sp|Q05609|CTR1_ARATH Serine/threonine-protein kinase CTR1 OS=Arabidopsis thaliana OX=3702 GN=CTR1 PE=1 SV=1 Length=821 Score = 94.0 bits (232), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 79/280 (28%), Positives = 130/280 (46%), Gaps = 42/280 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V + G VAVK L + D + + + +E+ I++ L H +I+ Sbjct 557 IGAGSFGTVHRAEW------HGSDVAVKILMEQDFHAERVNEFLREVAIMKRLRHPNIVL 610 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G +L +V EY+ GSL L R + + L A + +GM YLH + Sbjct 611 FMGAVTQ--PPNLSIVTEYLSRGSLYRLLHKSGAREQLDERRRLSMAYDVAKGMNYLHNR 668 Query 1018 H--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + +HRDL + N+L+D VK+ DFGL++ + + + +P W APE L++ Sbjct 669 NPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRL--KASTFLSSKSAAGTPE-WMAPEVLRD 725 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSP-----PTKFLELIGIAQGQMTVLRLTELLER 1130 SDV+SFGV L+EL T Q P P + + +G + Sbjct 726 EPSNEKSDVYSFGVILWELATL----QQPWGNLNPAQVVAAVGF---------------K 766 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +RL P +V +++ CW E RP+F ++ +L+ Sbjct 767 CKRLEIPRNLNPQVAAIIEGCWTNEPWKRPSFATIMDLLR 806 Score = 65.5 bits (158), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 63/246 (26%), Positives = 114/246 (46%), Gaps = 22/246 (9%) Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 G ++ V + + H + F ++M ++ H ++ G + P +VTEY+ G Sbjct 572 GSDVAVKILMEQDFHAERVNEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRG 631 Query 694 PLDVWLRRE--RGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAE 749 L L + R + ++ +A +A ++YL N+N +VH ++ N+L+ + Sbjct 632 SLYRLLHKSGAREQLDERRRLSMAYDVAKGMNYLHNRNPPIVHRDLKSPNLLVDK----- 686 Query 750 GTSPFIKLSDPGVG-LGA---LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 +K+ D G+ L A LS + W+APE L ++ + D + FG L Sbjct 687 --KYTVKVCDFGLSRLKASTFLSSKSAAGTPEWMAPEVLRDEPSNEKS--DVYSFGVILW 742 Query 806 EICFDGEAPLQSRSPSE---KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 E+ + P + +P++ F ++ +P PQ+A + C T EP +RPSF TI Sbjct 743 ELA-TLQQPWGNLNPAQVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNEPWKRPSFATI 801 Query 863 LRDLTR 868 + DL R Sbjct 802 M-DLLR 806 >sp|C0LGE0|Y1765_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g07650 OS=Arabidopsis thaliana OX=3702 GN=At1g07650 PE=1 SV=1 Length=1014 Score = 94.4 bits (233), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 86/289 (30%), Positives = 132/289 (46%), Gaps = 38/289 (13%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R +GEG FG S+Y + + G+++AVK L A +R + EI ++ L H +++ Sbjct 682 RKIGEGGFG--SVYKGELSE---GKLIAVKQLSAKSRQGNRE-FVNEIGMISALQHPNLV 735 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSL------RDYLPRHSIGLAQLLLFAQQICEGMAYL 1014 K GCC + + L LV EY+ L +D R + + I +G+ +L Sbjct 736 KLYGCCVEGNQ--LILVYEYLENNCLSRALFGKDESSRLKLDWSTRKKIFLGIAKGLTFL 793 Query 1015 HAQHYI---HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 H + I HRD+ A NVLLD D KI DFGLAK +G+ + R G + + APE Sbjct 794 HEESRIKIVHRDIKASNVLLDKDLNAKISDFGLAKLNDDGNTHISTRIAG--TIGYMAPE 851 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQMTVLRLTELLER 1130 +DV+SFGV E+++ ++ PT+ F+ L+ A L ER Sbjct 852 YAMRGYLTEKADVYSFGVVALEIVSGKSNTNFRPTEDFVYLLDWAY---------VLQER 902 Query 1131 GERLPRPDKCPCEVYH-----LMKN----CWETEASFRPTFENLIPILK 1170 G L D Y LM N C + RPT ++ +++ Sbjct 903 GSLLELVDPTLASDYSEEEAMLMLNVALMCTNASPTLRPTMSQVVSLIE 951 Score = 53.9 bits (128), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 78/328 (24%), Positives = 130/328 (40%), Gaps = 64/328 (20%) Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 +RG T L Q+ D ++T+ +G+G +VY+G L EGK+ Sbjct 656 LRGLDLQTGTFTLRQIK-AATDNFDVTR--KIGEGGFGSVYKGEL--------SEGKL-- 702 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 + +K L F ++S + H +L ++G CV G + Sbjct 703 ---------------IAVKQLSAKSRQGNREFVNEIGMISALQHPNLVKLYGCCVEGNQL 747 Query 684 IMVTEYVEHGPLDVWL--RRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVC 736 I+V EY+E+ L L + E + + W + + +A L++L ++ +VH ++ Sbjct 748 ILVYEYLENNCLSRALFGKDESSRLKLDWSTRKKIFLGIAKGLTFLHEESRIKIVHRDIK 807 Query 737 GRNILLARLGLAEGTSPF--IKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTA 794 N+LL + L S F KL+D G I ++APE G L+ Sbjct 808 ASNVLLDK-DLNAKISDFGLAKLNDDG---NTHISTRIAGTIGYMAPEYAMRGY--LTEK 861 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEK-------EHFYQRQHRLPEPSCPQLATLTSQ 847 D + FG LEI G++ R P+E + Q + L E P LA+ S+ Sbjct 862 ADVYSFGVVALEIV-SGKSNTNFR-PTEDFVYLLDWAYVLQERGSLLELVDPTLASDYSE 919 Query 848 ------------CLTYEPTQRPSFRTIL 863 C PT RP+ ++ Sbjct 920 EEAMLMLNVALMCTNASPTLRPTMSQVV 947 >sp|Q9LW83|CE101_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase CES101 OS=Arabidopsis thaliana OX=3702 GN=CES101 PE=2 SV=2 Length=850 Score = 94.0 bits (232), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 76/219 (35%), Positives = 105/219 (48%), Gaps = 24/219 (11%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG---TGEMVAVKALKADCGPQHRSGW 944 + F Y LGEG FG P G GE VA+K L G Q + Sbjct 518 ESVAFATDYFSDANKLGEGGFG--------PVYKGRLIDGEEVAIKRLSLASG-QGLVEF 568 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLL 1002 K E ++ L H +++K GCC ++ EK L+ EY+P SL +L P I L L Sbjct 569 KNEAMLIAKLQHTNLVKLLGCCVEKDEK--MLIYEYMPNKSLDYFLFDPLRKIVLDWKLR 626 Query 1003 F--AQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 F + I +G+ YLH IHRD+ A N+LLD D KI DFG+A+ G + + Sbjct 627 FRIMEGIIQGLLYLHKYSRLKVIHRDIKAGNILLDEDMNPKISDFGMARIF--GAQESKA 684 Query 1058 REDGDSPVFWY-APECLKEYKFYYASDVWSFGVTLYELL 1095 + F Y +PE +E F SDV+SFGV + E++ Sbjct 685 NTKRVAGTFGYMSPEYFREGLFSAKSDVFSFGVLMLEII 723 Score = 54.7 bits (130), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 66/271 (24%), Positives = 110/271 (41%), Gaps = 46/271 (17%) Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 P+ GR E V +K L + + F A L++++ HT+L + G CV E ++ Sbjct 540 PVYKGRLIDGE-EVAIKRLSLASGQGLVEFKNEAMLIAKLQHTNLVKLLGCCVEKDEKML 598 Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKM--VVAQQLASALSYLENKN---LVHGNVCGRNI 740 + EY+ + LD +L + + WK+ + + + L YL + ++H ++ NI Sbjct 599 IYEYMPNKSLDYFLFDPLRKIVLDWKLRFRIMEGIIQGLLYLHKYSRLKVIHRDIKAGNI 658 Query 741 LLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIP----WLAPECLPGGANSLSTA 794 L L E +P K+SD G+ GA + +R+ +++PE G S Sbjct 659 L-----LDEDMNP--KISDFGMARIFGAQESKANTKRVAGTFGYMSPEYFREGL--FSAK 709 Query 795 MDKWGFGATLLEIC---------FDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------- 837 D + FG +LEI D E PL R + +PS Sbjct 710 SDVFSFGVLMLEIICGRKNNSFHHDSEGPLNLIVHVWNLFKENRVREVIDPSLGDSAVEN 769 Query 838 -----CPQLATLTSQCLTYEPTQRPSFRTIL 863 C Q+A L C+ RPS ++ Sbjct 770 PQVLRCVQVALL---CVQQNADDRPSMLDVV 797 >sp|Q852Q2|OSK1_ORYSJ Serine/threonine protein kinase OSK1 OS=Oryza sativa subsp. japonica OX=39947 GN=OSK1 PE=1 SV=1 Length=505 Score = 92.8 bits (229), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 73/200 (37%), Positives = 100/200 (50%), Gaps = 16/200 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEH 958 + LG G FGKV + + TG VA+K L + + K+EI ILR H H Sbjct 18 KTLGIGSFGKVKI----AEHILTGHKVAIKILNRRKIKSMEMEEKVKREIKILRLFMHPH 73 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 II+ + + + +VMEYV G L DY+ + + + F QQI G+ Y H Sbjct 74 IIRLYEVIDTPAD--IYVVMEYVKSGELFDYIVEKGRLQEEEARRFFQQIISGVEYCHRN 131 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL N+LLD+ VKI DFGL+ + +GH ++ SP + APE + K Sbjct 132 MVVHRDLKPENLLLDSKCNVKIADFGLSNVMRDGH---FLKTSCGSPNY-AAPEVISG-K 186 Query 1078 FYYA--SDVWSFGVTLYELL 1095 Y DVWS GV LY LL Sbjct 187 LYAGPEVDVWSCGVILYALL 206 Score = 34.7 bits (78), Expect = 6.5, Method: Compositional matrix adjust. Identities = 45/202 (22%), Positives = 81/202 (40%), Gaps = 18/202 (9%) Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726 H H+ ++ V + +V EYV+ G L ++ E+G + QQ+ S + Y Sbjct 71 HPHIIRLYEVIDTPADIYVVMEYVKSGELFDYIV-EKGRLQEEEARRFFQQIISGVEYCH 129 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-----WLAP 781 +VH ++ N+LL + +K++D GL + R+ + + AP Sbjct 130 RNMVVHRDLKPENLLL-------DSKCNVKIAD--FGLSNVMRDGHFLKTSCGSPNYAAP 180 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQ 840 E + G + +D W G L + G P + P+ + + LP P Sbjct 181 EVISGKLYA-GPEVDVWSCGVILYALLC-GTLPFDDENIPNLFKKIKGGIYTLPSHLSPL 238 Query 841 LATLTSQCLTYEPTQRPSFRTI 862 L + L +P +R + R I Sbjct 239 ARDLIPRMLVVDPMKRITIREI 260 >sp|Q94C95|ATG1A_ARATH Serine/threonine-protein kinase ATG1a OS=Arabidopsis thaliana OX=3702 GN=ATG1A PE=1 SV=1 Length=626 Score = 93.2 bits (230), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 68/200 (34%), Positives = 106/200 (53%), Gaps = 17/200 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G F V L + +G VAVK + K P+ R +EI IL T+ H +II+ Sbjct 16 IGSGSFAVVWL----AKHRSSGLEVAVKEIDKKLLSPKVRDNLLKEISILSTIDHPNIIR 71 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + E G++ + LV+EY G L Y+ RH + A F +Q+ G+ L +H+I Sbjct 72 FYEAIE-TGDR-IFLVLEYCSGGDLAGYINRHGKVPEAVAKHFMRQLALGLQVLQEKHFI 129 Query 1021 HRDLAARNVLLDNDR---LVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLKEY 1076 HRDL +N+LL + L+KIGDFG A+++ PE + E + APE ++ Sbjct 130 HRDLKPQNLLLSSKEVTPLLKIGDFGFARSLTPES-----MAETFCGSPLYMAPEIIRNQ 184 Query 1077 KFYYASDVWSFGVTLYELLT 1096 K+ +D+WS G L++L+T Sbjct 185 KYDAKADLWSAGAILFQLVT 204 Score = 57.4 bits (137), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 60/246 (24%), Positives = 100/246 (41%), Gaps = 22/246 (9%) Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 K+L P D L + S++S + H ++ + G +V EY G L ++ R Sbjct 44 KLLSPKVRDNLL---KEISILSTIDHPNIIRFYEAIETGDRIFLVLEYCSGGDLAGYINR 100 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 G VP A +QLA L L+ K+ +H ++ +N+LL+ ++ +P +K+ D G Sbjct 101 -HGKVPEAVAKHFMRQLALGLQVLQEKHFIHRDLKPQNLLLS----SKEVTPLLKIGDFG 155 Query 762 VGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 +L+ E E ++APE + D W GA L ++ G+ P Sbjct 156 FA-RSLTPESMAETFCGSPLYMAPEIIRN--QKYDAKADLWSAGAILFQLV-TGKPPFDG 211 Query 818 RSPSEKEHFYQRQHRLPEPSC------PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 + + H R L P P L L P +R +FR + +P Sbjct 212 NNHIQLFHNIVRDTELKFPEDTRNEIHPDCVDLCRSLLRRNPIERLTFREFFNHMFLREP 271 Query 872 HNLADV 877 + DV Sbjct 272 RQIPDV 277 >sp|Q53UA7|TAOK3_RAT Serine/threonine-protein kinase TAO3 OS=Rattus norvegicus OX=10116 GN=Taok3 PE=1 SV=1 Length=898 Score = 94.0 bits (232), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 71/203 (35%), Positives = 102/203 (50%), Gaps = 23/203 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDILRTLYH 956 + ++G G FG V Y TN T E+VA+K + + G Q W+ +E+ L+ L H Sbjct 27 LHEIGHGSFGAV----YFATNAHTNEVVAIKKM-SYSGKQTHEKWQDILKEVRFLQQLKH 81 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYL 1014 + I+YKGC E + LVMEY LGS D L H L ++ + A +G+AYL Sbjct 82 PNTIEYKGCY--LKEHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQGLAYL 138 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--- 1071 H IHRD+ A N+LL VK+ DFG A + + +P +W APE Sbjct 139 HFHSLIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFV------GTP-YWMAPEVIL 191 Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094 + E ++ D+WS G+T EL Sbjct 192 AMDEGQYDGKVDIWSLGITCIEL 214 Score = 34.7 bits (78), Expect = 7.8, Method: Compositional matrix adjust. Identities = 49/214 (23%), Positives = 75/214 (35%), Gaps = 42/214 (20%) Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781 L+YL +L+H ++ NILL G +KL+D G A V W+AP Sbjct 135 LAYLHFHSLIHRDIKAGNILLTEPGQ-------VKLADFGSASMASPANSFVGTPYWMAP 187 Query 782 EC-LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840 E L +D W G T +E+ + S H Q P Sbjct 188 EVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQN-------DSPT 240 Query 841 LAT---------LTSQCLTYEPTQRPSFRTILR-DLTRLQ--PHNLADVLTVNPDSPASD 888 L + CL P +RP+ +LR D R + P L D++ D+ Sbjct 241 LQSREWTDSFRRFVDYCLHKIPQERPAAAELLRHDFIRRERPPRVLIDLIQRTKDA---- 296 Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922 +R+L + K+ + T +G Sbjct 297 -----------VRELDNLQYRKMKKILFQETRNG 319 >sp|O42565|LIMK1_XENLA LIM domain kinase 1 OS=Xenopus laevis OX=8355 GN=limk1 PE=2 SV=1 Length=615 Score = 93.2 bits (230), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 62/199 (31%), Positives = 100/199 (50%), Gaps = 13/199 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG+ T+ TGE++ +K L R+ K E+ ++R L H H++K+ Sbjct 320 LGRGCFGQA----IKVTHRVTGEVMVMKELIRFDEETQRTFLK-EVKVMRCLEHPHVLKF 374 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYI 1020 G +K L + EY+P G+LR + Q + FA+ I GM YLH+ + I Sbjct 375 IGVL--YKDKRLNFITEYIPGGTLRRVIKSMDTHCPWNQRVSFARDIAAGMTYLHSMNII 432 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV----FWYAPECLKEY 1076 HRDL + N L+ D + + +FGL++ +PE R V +W APE + Sbjct 433 HRDLNSHNCLVREDGGLVVANFGLSRLIPEETRDLRKDRRKRYTVVGNPYWMAPEMINGR 492 Query 1077 KFYYASDVWSFGVTLYELL 1095 + + DV+SFG+ + E++ Sbjct 493 SYDESVDVFSFGIVICEII 511 Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 51/228 (22%), Positives = 90/228 (39%), Gaps = 9/228 (4%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +V+K L + F + +M + H H+ GV + +TEY+ G L Sbjct 340 MVMKELIRFDEETQRTFLKEVKVMRCLEHPHVLKFIGVLYKDKRLNFITEYIPGGTLRRV 399 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG----LAEGTSPF 754 ++ H P ++ A+ +A+ ++YL + N++H ++ N L+ G G S Sbjct 400 IKSMDTHCPWNQRVSFARDIAAGMTYLHSMNIIHRDLNSHNCLVREDGGLVVANFGLSRL 459 Query 755 IKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--FDGE 812 I + R V W+APE + G S ++D + FG + EI + + Sbjct 460 IPEETRDLRKDRRKRYTVVGNPYWMAPEMING--RSYDESVDVFSFGIVICEIIGLVNAD 517 Query 813 APLQSRSPSEKEHFYQRQHRLPEPSC-PQLATLTSQCLTYEPTQRPSF 859 R+ + R P+C P C +P +RP F Sbjct 518 PDYLPRTMDFGLNVRAFLDRFCPPNCPPGFFPSAVLCCDLDPEKRPRF 565 >sp|Q9NGW9|MKCB_DICDI Probable serine/threonine-protein kinase mkcB OS=Dictyostelium discoideum OX=44689 GN=mkcB PE=2 SV=1 Length=714 Score = 93.6 bits (231), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 63/218 (29%), Positives = 107/218 (49%), Gaps = 17/218 (8%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 +P + K Y K +G+G FG V Y + +VA+K + Q + ++ E Sbjct 430 EPALLKKMY-KDSDQVGKGGFGTV----YFAKSTKEKRLVAIKKMPHVTKRQQQQNFR-E 483 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 IL H +I+K C D+ + +L +VME++ G+ + L A+++ Sbjct 484 AAILAKCDHPNIVKLHTCHIDK-DSNLWIVMEFMEGGTFEEAAKAWKFNENNLAYVAKEL 542 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 +G+ YLH H +HRDL + N+++ + VK+ DFGL + V + V SP FW Sbjct 543 LKGLQYLHENHMVHRDLKSANIMMSVEGKVKLIDFGLCEDVATSTPMHMV----GSP-FW 597 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 APE +++ D+WSF ++L E+ ++Q PP Sbjct 598 MAPEMIQQKYHSTPVDIWSFAISLLEM-----ANQRPP 630 Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust. Identities = 39/162 (24%), Positives = 74/162 (46%), Gaps = 26/162 (16%) Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKM-- 712 + A+++++ H ++ +H + N+ +V E++E G + + AWK Sbjct 481 FREAAILAKCDHPNIVKLHTCHIDKDSNLWIVMEFMEGGTFEEAAK--------AWKFNE 532 Query 713 ----VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV--GLGA 766 VA++L L YL ++VH ++ NI+++ G +KL D G+ + Sbjct 533 NNLAYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEGK-------VKLIDFGLCEDVAT 585 Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + V W+APE + + ST +D W F +LLE+ Sbjct 586 STPMHMVGSPFWMAPEMIQQKYH--STPVDIWSFAISLLEMA 625 >sp|Q04759|KPCT_HUMAN Protein kinase C theta type OS=Homo sapiens OX=9606 GN=PRKCQ PE=1 SV=3 Length=706 Score = 93.6 bits (231), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 70/209 (33%), Positives = 103/209 (49%), Gaps = 23/209 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI-LRTLYHEHIIK 961 LG+G FGKV L + TN + A+KALK D ++ + +L EH Sbjct 386 LGKGSFGKVFLAEFKKTN----QFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFL 441 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 C Q +++L VMEY+ G L ++ H L++ +A +I G+ +LH++ + Sbjct 442 THMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIV 501 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WYAPECLKE 1075 +RDL N+LLD D +KI DFG+ K G D + F + APE L Sbjct 502 YRDLKLDNILLDKDGHIKIADFGMCKENMLG--------DAKTNTFCGTPDYIAPEILLG 553 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 K+ ++ D WSFGV LYE+L QSP Sbjct 554 QKYNHSVDWWSFGVLLYEMLI----GQSP 578 >sp|A8C984|MYLK3_DANRE Myosin light chain kinase 3 OS=Danio rerio OX=7955 GN=mylk3 PE=2 SV=1 Length=715 Score = 93.6 bits (231), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 71/202 (35%), Positives = 105/202 (52%), Gaps = 23/202 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG+V C + + +G +A K +K G + R K EI ++ L H ++I+ Sbjct 410 LGGGRFGQVH-KCAELS---SGLTLAAKIIKVR-GMKERDEVKNEIGVMNQLNHVNLIQL 464 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020 E + +L L+MEYV G L + + S L +L ++F +QICEG+ YLH Q+ + Sbjct 465 YDAFESRT--NLTLIMEYVEGGELFERIIDESYQLTELDAIVFTRQICEGVQYLHQQYIL 522 Query 1021 HRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVRE----DGDSPVFWYAPECLK 1074 H DL N+L N +KI DFGLA+ YR RE + +P F APE + Sbjct 523 HLDLKPENILCVNSTGNQIKIIDFGLARK-------YRPREKLKVNFGTPEFL-APEVVN 574 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + +D+WS GV Y LL+ Sbjct 575 YDFVSFPTDMWSVGVITYMLLS 596 Score = 35.4 bits (80), Expect = 3.8, Method: Compositional matrix adjust. Identities = 37/165 (22%), Positives = 69/165 (42%), Gaps = 11/165 (7%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 +M+Q++H +L ++ ++ EYVE G L + E + +V +Q+ Sbjct 452 VMNQLNHVNLIQLYDAFESRTNLTLIMEYVEGGELFERIIDESYQLTELDAIVFTRQICE 511 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---P 777 + YL + ++H ++ NIL T IK+ D G+ RE+ Sbjct 512 GVQYLHQQYILHLDLKPENILCVN-----STGNQIKIIDFGLARKYRPREKLKVNFGTPE 566 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 +LAPE + + +S D W G + + G +P + +E Sbjct 567 FLAPEVV--NYDFVSFPTDMWSVG-VITYMLLSGLSPFMGDNDAE 608 >sp|Q8VHF0|MARK3_RAT MAP/microtubule affinity-regulating kinase 3 OS=Rattus norvegicus OX=10116 GN=Mark3 PE=1 SV=1 Length=797 Score = 93.6 bits (231), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 72/211 (34%), Positives = 103/211 (49%), Gaps = 16/211 (8%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQE 947 P + + R LK I G+G+F KV L + T G VA+K + K P +E Sbjct 51 PHIGNYRLLKTI---GKGNFAKVKLARHILT----GREVAIKIIDKTQLNPTSLQKLFRE 103 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQ 1006 + I++ L H +I+K E EK+L L+MEY G + DYL H + + +Q Sbjct 104 VRIMKILNHPNIVKLFEVIET--EKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 161 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I + Y H + +HRDL A N+LLD D +KI DFG + G + G P Sbjct 162 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKITDFGFSNEFTVGSKLDTF--CGSPP-- 217 Query 1067 WYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096 + APE + K+ DVWS GV LY L++ Sbjct 218 YAAPELFQGKKYDGPEVDVWSLGVILYTLVS 248 Score = 40.0 bits (92), Expect = 0.14, Method: Compositional matrix adjust. Identities = 49/236 (21%), Positives = 93/236 (39%), Gaps = 22/236 (9%) Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K++D + + + +M ++H ++ + V ++ EY G + Sbjct 82 VAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVF 141 Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 +L H M K A+ Q+ SA+ Y K +VH ++ N+LL Sbjct 142 DYLV---AHGRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLL-------DADMN 191 Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 IK++D G + +++ P+ APE G +D W G L + Sbjct 192 IKITDFGFS-NEFTVGSKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLV-S 248 Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 G P ++ E +E + ++R+P L + L P +R + I++D Sbjct 249 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMKD 304 >sp|Q9ZUE0|PEK12_ARATH Proline-rich receptor-like protein kinase PERK12 OS=Arabidopsis thaliana OX=3702 GN=PERK12 PE=2 SV=2 Length=720 Score = 93.6 bits (231), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 74/204 (36%), Positives = 101/204 (50%), Gaps = 24/204 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG C G++VAVK LKA G R +K E++I+ ++H H++ Sbjct 377 LGEGGFG-----CVYKGTLQDGKVVAVKQLKAGSGQGDRE-FKAEVEIISRVHHRHLVSL 430 Query 963 KG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHA 1016 G C DQ L+ EYV +L +L H GL L + A +G+AYLH Sbjct 431 VGYCISDQHR---LLIYEYVSNQTLEHHL--HGKGLPVLEWSKRVRIAIGSAKGLAYLHE 485 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072 IHRD+ + N+LLD++ ++ DFGLA+ + R G F Y APE Sbjct 486 DCHPKIIHRDIKSANILLDDEYEAQVADFGLARLNDTTQTHVSTRVMG---TFGYLAPEY 542 Query 1073 LKEYKFYYASDVWSFGVTLYELLT 1096 K SDV+SFGV L EL+T Sbjct 543 ASSGKLTDRSDVFSFGVVLLELVT 566 Score = 41.2 bits (95), Expect = 0.070, Method: Compositional matrix adjust. Identities = 66/269 (25%), Positives = 106/269 (39%), Gaps = 50/269 (19%) Query 574 LNLSQLSFHRVDQKEITQ----LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 L Q F + EITQ + LG+G VY+G L ++GK+ Sbjct 352 LGSGQTHFSYEELAEITQGFARKNILGEGGFGCVYKGTL--------QDGKV-------- 395 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 V +K L F ++S+V H HL + G C+ +++ EY Sbjct 396 ---------VAVKQLKAGSGQGDREFKAEVEIISRVHHRHLVSLVGYCISDQHRLLIYEY 446 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASA--LSYLENK---NLVHGNVCGRNILLAR 744 V + L+ L +G + W V + SA L+YL ++H ++ NILL Sbjct 447 VSNQTLEHHLHG-KGLPVLEWSKRVRIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDD 505 Query 745 LGLAEGTSPFIKLSDPGVG-LGALSREERVERI----PWLAPECLPGGANSLSTAMDKWG 799 A+ ++D G+ L ++ R+ +LAPE G L+ D + Sbjct 506 EYEAQ-------VADFGLARLNDTTQTHVSTRVMGTFGYLAPEYASSG--KLTDRSDVFS 556 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 FG LLE+ G P+ P +E + Sbjct 557 FGVVLLELV-TGRKPVDQTQPLGEESLVE 584 >sp|O81906|B120_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase B120 OS=Arabidopsis thaliana OX=3702 GN=B120 PE=2 SV=1 Length=849 Score = 93.6 bits (231), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 86/281 (31%), Positives = 129/281 (46%), Gaps = 18/281 (6%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 K +LG G FG V + G +AVK L G Q +K EI ++ L H + Sbjct 531 KENELGRGGFGPVYKGVLED-----GREIAVKRLSGKSG-QGVDEFKNEIILIAKLQHRN 584 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYL 1014 +++ GCC + EK LV EY+P SL +L + I + I G+ YL Sbjct 585 LVRLLGCCFEGEEK--MLVYEYMPNKSLDFFLFDETKQALIDWKLRFSIIEGIARGLLYL 642 Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAP 1070 H IHRDL NVLLD + KI DFG+A+ +E VR G + +P Sbjct 643 HRDSRLRIIHRDLKVSNVLLDAEMNPKISDFGMARIFGGNQNEANTVRVVGTYG--YMSP 700 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E E F SDV+SFGV L E+++ ++ ++ LIG A T R EL++ Sbjct 701 EYAMEGLFSVKSDVYSFGVLLLEIVSGKRNTSLRSSEHGSLIGYAWYLYTHGRSEELVDP 760 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 R+ + H+ C + A+ RP +++ +L++ Sbjct 761 KIRVTCSKREALRCIHVAMLCVQDSAAERPNMASVLLMLES 801 Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 42/161 (26%), Positives = 74/161 (46%), Gaps = 14/161 (9%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM-- 712 F L++++ H +L + G C G E ++V EY+ + LD +L E + WK+ Sbjct 570 FKNEIILIAKLQHRNLVRLLGCCFEGEEKMLVYEYMPNKSLDFFLFDETKQALIDWKLRF 629 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSRE 770 + + +A L YL + + + R++ ++ + L +P K+SD G+ G E Sbjct 630 SIIEGIARGLLYLHRDSRLR--IIHRDLKVSNVLLDAEMNP--KISDFGMARIFGGNQNE 685 Query 771 ERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 R+ +++PE G S D + FG LLEI Sbjct 686 ANTVRVVGTYGYMSPEYAMEGL--FSVKSDVYSFGVLLLEI 724 >sp|P92958|KIN11_ARATH SNF1-related protein kinase catalytic subunit alpha KIN11 OS=Arabidopsis thaliana OX=3702 GN=KIN11 PE=1 SV=1 Length=512 Score = 92.4 bits (228), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 72/200 (36%), Positives = 100/200 (50%), Gaps = 16/200 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEH 958 + LG G FGKV + + TG VA+K L + + ++EI ILR H H Sbjct 24 KTLGIGSFGKVKI----AEHVVTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPH 79 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 II+ E + + +VMEYV G L DY+ + + + F QQI G+ Y H Sbjct 80 IIRQYEVIETTSD--IYVVMEYVKSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRN 137 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL N+LLD+ +KI DFGL+ + +GH ++ SP + APE + K Sbjct 138 MVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDGH---FLKTSCGSPNY-AAPEVISG-K 192 Query 1078 FYYA--SDVWSFGVTLYELL 1095 Y DVWS GV LY LL Sbjct 193 LYAGPEVDVWSCGVILYALL 212 >sp|Q9FID9|Y5389_ARATH Probable receptor-like protein kinase At5g38990 OS=Arabidopsis thaliana OX=3702 GN=At5g38990 PE=2 SV=1 Length=880 Score = 93.6 bits (231), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 67/202 (33%), Positives = 97/202 (48%), Gaps = 16/202 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V Y DG +VAVK L+ Q + E+++L L H H++ Sbjct 531 IGVGGFGSV----YKGRIDGGATLVAVKRLEITSN-QGAKEFDTELEMLSKLRHVHLVSL 585 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ--QIC----EGMAYLHA 1016 G C+D E + LV EY+P G+L+D+L R L + + +IC G+ YLH Sbjct 586 IGYCDDDNE--MVLVYEYMPHGTLKDHLFRRDKASDPPLSWKRRLEICIGAARGLQYLHT 643 Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRD+ N+LLD + + K+ DFGL++ P V + PE Sbjct 644 GAKYTIIHRDIKTTNILLDENFVAKVSDFGLSRVGPTSASQTHVSTVVKGTFGYLDPEYY 703 Query 1074 KEYKFYYASDVWSFGVTLYELL 1095 + SDV+SFGV L E+L Sbjct 704 RRQILTEKSDVYSFGVVLLEVL 725 Score = 51.2 bits (121), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 57/209 (27%), Positives = 91/209 (44%), Gaps = 23/209 (11%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 GR G V +K L+ + + A F ++S++ H HL + G C E ++V EY Sbjct 542 GRIDGGATLVAVKRLEITSNQGAKEFDTELEMLSKLRHVHLVSLIGYCDDDNEMVLVYEY 601 Query 690 VEHGPL-DVWLRRERGHV-PMAWK--MVVAQQLASALSYLENK---NLVHGNVCGRNILL 742 + HG L D RR++ P++WK + + A L YL ++H ++ NILL Sbjct 602 MPHGTLKDHLFRRDKASDPPLSWKRRLEICIGAARGLQYLHTGAKYTIIHRDIKTTNILL 661 Query 743 ARLGLAEGTSPFIKLSDPG---VGLGALSREERVERIP----WLAPECLPGGANSLSTAM 795 +A K+SD G VG + S+ + +L PE L+ Sbjct 662 DENFVA-------KVSDFGLSRVGPTSASQTHVSTVVKGTFGYLDPEYYR--RQILTEKS 712 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKE 824 D + FG LLE+ +QS P + + Sbjct 713 DVYSFGVVLLEVLCCRPIRMQSVPPEQAD 741 >sp|Q05512|MARK2_MOUSE Serine/threonine-protein kinase MARK2 OS=Mus musculus OX=10090 GN=Mark2 PE=1 SV=3 Length=776 Score = 93.6 bits (231), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 76/232 (33%), Positives = 114/232 (49%), Gaps = 18/232 (8%) Query 870 QPHNLADVLTVNPDSPASD--PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 +P + +++L + ++D P + + R LK I G+G+F KV L + TG+ V Sbjct 27 KPSSKSNMLRGRNSATSADEQPHIGNYRLLKTI---GKGNFAKVKLARHI----LTGKEV 79 Query 928 AVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 AVK + K +E+ I++ L H +I+K E EK+L LVMEY G + Sbjct 80 AVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIET--EKTLYLVMEYASGGEV 137 Query 987 RDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 DYL H + + +QI + Y H + +HRDL A N+LLD D +KI DFG + Sbjct 138 FDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFS 197 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096 G++ G P + APE + K DVWS GV LY L++ Sbjct 198 NEFTFGNKLDTF--CGSPP--YAAPELFQGKKIDGPEVDVWSLGVILYTLVS 245 Score = 39.7 bits (91), Expect = 0.21, Method: Compositional matrix adjust. Identities = 50/236 (21%), Positives = 95/236 (40%), Gaps = 22/236 (9%) Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K++D + + + + +M ++H ++ + V +V EY G + Sbjct 79 VAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVF 138 Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 +L H M K A+ Q+ SA+ Y K +VH ++ N+LL Sbjct 139 DYLV---AHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLL-------DADMN 188 Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 IK++D G + +++ P+ APE G +D W G L + Sbjct 189 IKIADFGFS-NEFTFGNKLDTFCGSPPYAAPELFQGKKID-GPEVDVWSLGVILYTLV-S 245 Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 G P ++ E +E + ++R+P L + L P++R + I++D Sbjct 246 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKD 301 >sp|B3MH43|PTK7_DROAN Tyrosine-protein kinase-like otk OS=Drosophila ananassae OX=7217 GN=otk PE=3 SV=1 Length=1037 Score = 94.0 bits (232), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 64/257 (25%), Positives = 122/257 (47%), Gaps = 32/257 (12%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 ++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY G Sbjct 784 QLVLVKALNKVKDEQACQEFRRQLDLLRGISHKGVVRLFGLCREKDPH--YMVLEYTDWG 841 Query 985 SLRDYLPRHS----------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARN 1028 L+ +L + + +Q+L A QI GM ++ + HRDLA RN Sbjct 842 DLKQFLLATAGKVNTASAAATSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRN 901 Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 ++ ++ +VK+ L K EY++ R + P+ W APEC++E ++ SD++++G Sbjct 902 CVISSEFIVKVSYPALCKD-KYSREYHKHR-NTLLPIRWLAPECIQEDEYTTKSDIFAYG 959 Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148 V ++EL +++ P + I + Q L T + P + ++ Sbjct 960 VVVWELFNQ--ATKLPHEELTNEQVIQKSQAGTLEWT----------VAESTPDSLREIL 1007 Query 1149 KNCWETEASFRPTFENL 1165 +CW + RP+F L Sbjct 1008 LSCWVSNPKERPSFSQL 1024 Score = 53.9 bits (128), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 60/256 (23%), Positives = 102/256 (40%), Gaps = 37/256 (14%) Query 639 VVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V++K L+ + A F L+ +SH + + G+C + MV EY + G L Sbjct 786 VLVKALNKVKDEQACQEFRRQLDLLRGISHKGVVRLFGLCREKDPHYMVLEYTDWGDLKQ 845 Query 698 WLRRERGHVPMAWK--------------MVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 +L G V A + VA Q+A + + H ++ RN ++ Sbjct 846 FLLATAGKVNTASAAATSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRNCVI- 904 Query 744 RLGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDK 797 +S FI K+S P + SRE R I WLAPEC+ + +T D Sbjct 905 -------SSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQ--EDEYTTKSDI 955 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH-----RLPEPSCPQLATLTSQCLTYE 852 + +G + E+ F+ L + ++ + Q + E + L + C Sbjct 956 FAYGVVVWEL-FNQATKLPHEELTNEQVIQKSQAGTLEWTVAESTPDSLREILLSCWVSN 1014 Query 853 PTQRPSFRTILRDLTR 868 P +RPSF + L++ Sbjct 1015 PKERPSFSQLGAALSK 1030 >sp|O49545|BAME1_ARATH Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM1 OS=Arabidopsis thaliana OX=3702 GN=BAM1 PE=1 SV=1 Length=1003 Score = 93.6 bits (231), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 84/271 (31%), Positives = 127/271 (47%), Gaps = 38/271 (14%) Query 923 TGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 G++VAVK L A G H G+ EI L + H HI++ G C + E +L LV EY+ Sbjct 715 NGDLVAVKRLAAMSRGSSHDHGFNAEIQTLGRIRHRHIVRLLGFCSNH-ETNL-LVYEYM 772 Query 982 PLGSLRDYL-----------PRHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAAR 1027 P GSL + L R+ I L + +G+ YLH + +HRD+ + Sbjct 773 PNGSLGEVLHGKKGGHLHWDTRYKIAL--------EAAKGLCYLHHDCSPLIVHRDVKSN 824 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 N+LLD++ + DFGLAK + + + S + APE K SDV+SF Sbjct 825 NILLDSNFEAHVADFGLAKFLQDSGTSECMSAIAGS-YGYIAPEYAYTLKVDEKSDVYSF 883 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQ--GQMTVLRLTELLERGERLPRPDKCP---- 1141 GV L EL+T + P +F + + I Q +MT +L+ + PR P Sbjct 884 GVVLLELVT----GRKPVGEFGDGVDIVQWVRKMTDSNKDSVLKVLD--PRLSSIPIHEV 937 Query 1142 CEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 V+++ C E +A RPT ++ IL + Sbjct 938 THVFYVAMLCVEEQAVERPTMREVVQILTEI 968 Score = 43.1 bits (100), Expect = 0.020, Method: Compositional matrix adjust. Identities = 60/253 (24%), Positives = 105/253 (42%), Gaps = 45/253 (18%) Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGH 705 S HD F + ++ H H+ + G C N++V EY+ +G L +V ++ GH Sbjct 731 SSHD--HGFNAEIQTLGRIRHRHIVRLLGFCSNHETNLLVYEYMPNGSLGEVLHGKKGGH 788 Query 706 VPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILL--------ARLGLAEGTSPF 754 + + +A + A L YL + +VH +V NILL A GLA+ F Sbjct 789 LHWDTRYKIALEAAKGLCYLHHDCSPLIVHRDVKSNNILLDSNFEAHVADFGLAK----F 844 Query 755 IKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLST--AMDKWGFGATLLEICF--- 809 ++ S + A++ ++APE A +L D + FG LLE+ Sbjct 845 LQDSGTSECMSAIAGS-----YGYIAPEY----AYTLKVDEKSDVYSFGVVLLELVTGRK 895 Query 810 ------DGEAPLQ---SRSPSEKEHFYQ----RQHRLPEPSCPQLATLTSQCLTYEPTQR 856 DG +Q + S K+ + R +P + + C+ + +R Sbjct 896 PVGEFGDGVDIVQWVRKMTDSNKDSVLKVLDPRLSSIPIHEVTHVFYVAMLCVEEQAVER 955 Query 857 PSFRTILRDLTRL 869 P+ R +++ LT + Sbjct 956 PTMREVVQILTEI 968 >sp|Q6J9G0|STYK1_HUMAN Tyrosine-protein kinase STYK1 OS=Homo sapiens OX=9606 GN=STYK1 PE=1 SV=4 Length=422 Score = 91.3 bits (225), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 76/273 (28%), Positives = 122/273 (45%), Gaps = 43/273 (16%) Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKG 964 G + ++ DP+ + V +KALK G + I + L H+++++ +G Sbjct 126 GPIFRANMNTGDPSKPKS---VILKALKEPAGLHEVQDFLGRIQFHQYLGKHKNLVQLEG 182 Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLF----------AQQICEGMA 1012 CC ++ L +V+E V G L +L R + LL+ +Q+ + Sbjct 183 CCTEK--LPLYMVLEDVAQGDLLSFLWTCRRDVMTMDGLLYDLTEKQVYHIGKQVLLALE 240 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAP 1070 +L +H H D+AARN+L+ +D K+ GLA V Y R + P+ W AP Sbjct 241 FLQEKHLFHGDVAARNILMQSDLTAKLCGLGLAYEV-----YTRGAISSTQTIPLKWLAP 295 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLTELL 1128 E L +DVWSFG+ LYE++T + PPT L E L Sbjct 296 ERLLLRPASIRADVWSFGILLYEMVTLGAPPYPEVPPTSIL----------------EHL 339 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 +R + + RP C +Y +MK+CW + RP+ Sbjct 340 QRRKIMKRPSSCTHTMYSIMKSCWRWREADRPS 372 Score = 56.2 bits (134), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 61/214 (29%), Positives = 90/214 (42%), Gaps = 29/214 (14%) Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV--------PMAWKMV--VAQ 716 H +L + G C MV E V G L +L R V + K V + + Sbjct 174 HKNLVQLEGCCTEKLPLYMVLEDVAQGDLLSFLWTCRRDVMTMDGLLYDLTEKQVYHIGK 233 Query 717 QLASALSYLENKNLVHGNVCGRNILL-----ARL-GLAEGTSPFIKLSDPGVGLGALSRE 770 Q+ AL +L+ K+L HG+V RNIL+ A+L GL + + GA+S Sbjct 234 QVLLALEFLQEKHLFHGDVAARNILMQSDLTAKLCGLGLAYEVYTR--------GAISST 285 Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 + + + WLAPE L S+ D W FG L E+ G P P+ QR+ Sbjct 286 QTIP-LKWLAPERLLLRPASIRA--DVWSFGILLYEMVTLGAPPYPEVPPTSILEHLQRR 342 Query 831 HRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 + P SC + ++ C + RPS R + Sbjct 343 KIMKRPSSCTHTMYSIMKSCWRWREADRPSPREL 376 >sp|E9PT87|MYLK3_RAT Myosin light chain kinase 3 OS=Rattus norvegicus OX=10116 GN=Mylk3 PE=1 SV=1 Length=786 Score = 93.2 bits (230), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 79/244 (32%), Positives = 113/244 (46%), Gaps = 38/244 (16%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRD--------------LGEGHFGKVSLYCYDPTN 920 A+ V D A+ P F R + I+D LG G FG+V + T Sbjct 447 AEAAIVVLDDSAAPPAPFEHRVVS-IKDTLISTSYTVSQHEVLGGGRFGQV----HRCTE 501 Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 TG +A K +K + R K EI+I+ L H ++I+ E + S L+MEY Sbjct 502 RSTGLALAAKIIKVK-NIKDREDVKNEINIMNQLSHVNLIQLYDAFESK--NSFTLIMEY 558 Query 981 VPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYIHRDLAARNVLL--DNDRL 1036 V G L D + L +L +LF +QICEG+ YLH + +H DL N+L Sbjct 559 VDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQ 618 Query 1037 VKIGDFGLAKAVPEGHEYYRVRE----DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 +KI DFGLA+ Y+ RE + +P F APE + + +D+WS GV Y Sbjct 619 IKIIDFGLAR-------RYKPREKLKVNFGTPEF-LAPEVVNYEFVSFPTDMWSVGVITY 670 Query 1093 ELLT 1096 LL+ Sbjct 671 MLLS 674 Score = 34.7 bits (78), Expect = 6.1, Method: Compositional matrix adjust. Identities = 38/170 (22%), Positives = 72/170 (42%), Gaps = 11/170 (6%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 ++M+Q+SH +L ++ ++ EYV+ G L + E+ H+ ++ +Q+ Sbjct 529 NIMNQLSHVNLIQLYDAFESKNSFTLIMEYVDGGELFDRITDEKYHLTELDVVLFTRQIC 588 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776 + YL ++H ++ NIL T IK+ D G+ RE+ Sbjct 589 EGVHYLHQHYILHLDLKPENIL-----CVSQTGHQIKIIDFGLARRYKPREKLKVNFGTP 643 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 +LAPE + +S D W G + + G +P + +E +F Sbjct 644 EFLAPEVV--NYEFVSFPTDMWSVG-VITYMLLSGLSPFLGETDAETMNF 690 >sp|Q93YN1|CRPK1_ARATH Cold-responsive protein kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CRPK1 PE=1 SV=1 Length=390 Score = 90.9 bits (224), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 76/287 (26%), Positives = 127/287 (44%), Gaps = 39/287 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---EIDILRTLYHEHI 959 +GEG FG V C G++ A+K L A + R G K+ EI+++ + HE++ Sbjct 47 IGEGGFGSVYKGCLKD-----GKLAAIKVLSA----ESRQGVKEFLTEINVISEIQHENL 97 Query 960 IKYKGCC-------------EDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006 +K GCC E+ L Y G D+ R +I + Sbjct 98 VKLYGCCVEGNHRILVYNFLENNSLDKTLLAGGYTRSGIQFDWSSRANICVG-------- 149 Query 1007 ICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 + +G+A+LH + H IHRD+ A N+LLD KI DFGLA+ +P + R G Sbjct 150 VAKGLAFLHEEVRPHIIHRDIKASNILLDKYLSPKISDFGLARLMPPNMTHVSTRVAG-- 207 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVL 1122 + + APE + +D++SFGV L E+++ + + PT++ L+ A Sbjct 208 TIGYLAPEYAVRGQLTRKADIYSFGVLLMEIVSGRSNKNTRLPTEYQYLLERAWELYERN 267 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 L +L++ G + C + C + RP+ ++ +L Sbjct 268 ELVDLVDSGLNGVFDAEEACRYLKIGLLCTQDSPKLRPSMSTVVRLL 314 Score = 60.8 bits (146), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 66/259 (25%), Positives = 108/259 (42%), Gaps = 43/259 (17%) Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 +KVL F +++S++ H +L ++G CV G I+V ++E+ LD L Sbjct 68 IKVLSAESRQGVKEFLTEINVISEIQHENLVKLYGCCVEGNHRILVYNFLENNSLDKTLL 127 Query 701 R---ERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752 R + W + + +A L++L + +++H ++ NILL + S Sbjct 128 AGGYTRSGIQFDWSSRANICVGVAKGLAFLHEEVRPHIIHRDIKASNILLDKY-----LS 182 Query 753 PFIKLSDPGVGL----GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 P K+SD G+ RV I +LAPE G L+ D + FG L+EI Sbjct 183 P--KISDFGLARLMPPNMTHVSTRVAGTIGYLAPEYAVRG--QLTRKADIYSFGVLLMEI 238 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL-------------------PEPSCPQLATLTSQC 848 G + +R P+E ++ +R L E +C L + C Sbjct 239 -VSGRSNKNTRLPTEYQYLLERAWELYERNELVDLVDSGLNGVFDAEEACRYLK-IGLLC 296 Query 849 LTYEPTQRPSFRTILRDLT 867 P RPS T++R LT Sbjct 297 TQDSPKLRPSMSTVVRLLT 315 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 Length=753 Score = 93.2 bits (230), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 72/211 (34%), Positives = 103/211 (49%), Gaps = 16/211 (8%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQE 947 P + + R LK I G+G+F KV L + T G VA+K + K P +E Sbjct 51 PHIGNYRLLKTI---GKGNFAKVKLARHILT----GREVAIKIIDKTQLNPTSLQKLFRE 103 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQ 1006 + I++ L H +I+K E EK+L L+MEY G + DYL H + + +Q Sbjct 104 VRIMKILNHPNIVKLFEVIET--EKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQ 161 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I + Y H + +HRDL A N+LLD D +KI DFG + G + G P Sbjct 162 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTF--CGSPP-- 217 Query 1067 WYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096 + APE + K+ DVWS GV LY L++ Sbjct 218 YAAPELFQGKKYDGPEVDVWSLGVILYTLVS 248 Score = 38.5 bits (88), Expect = 0.52, Method: Compositional matrix adjust. Identities = 48/236 (20%), Positives = 93/236 (39%), Gaps = 22/236 (9%) Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K++D + + + +M ++H ++ + V ++ EY G + Sbjct 82 VAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVF 141 Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 +L H M K ++ Q+ SA+ Y K +VH ++ N+LL Sbjct 142 DYLV---AHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLL-------DADMN 191 Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 IK++D G + +++ P+ APE G +D W G L + Sbjct 192 IKIADFGFS-NEFTVGGKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLV-S 248 Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 G P ++ E +E + ++R+P L + L P +R + I++D Sbjct 249 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKD 304 >sp|O14920|IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta OS=Homo sapiens OX=9606 GN=IKBKB PE=1 SV=1 Length=756 Score = 93.2 bits (230), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 68/207 (33%), Positives = 100/207 (48%), Gaps = 23/207 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + N TGE +A+K + + P++R W EI I+R L H +++ Sbjct 21 LGTGGFGNVIRW----HNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVVAA 76 Query 963 KGCCEDQGEKSLQ------LVMEYVPLGSLRDYLPR--HSIGLAQ--LLLFAQQICEGMA 1012 + E G ++L L MEY G LR YL + + GL + +L I + Sbjct 77 RDVPE--GMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALR 134 Query 1013 YLHAQHYIHRDLAARNVLLDN--DRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH IHRDL N++L RL+ KI D G AK + +G + + + A Sbjct 135 YLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGS----LCTSFVGTLQYLA 190 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096 PE L++ K+ D WSFG +E +T Sbjct 191 PELLEQQKYTVTVDYWSFGTLAFECIT 217 >sp|Q9FLZ3|KIN12_ARATH SNF1-related protein kinase catalytic subunit alpha KIN12 OS=Arabidopsis thaliana OX=3702 GN=KIN12 PE=2 SV=1 Length=494 Score = 92.0 bits (227), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 71/200 (36%), Positives = 100/200 (50%), Gaps = 17/200 (9%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK----ADCGPQHRSGWKQEIDILRTLYH 956 + LG G F KV L + TG VA+K L + G + + ++EI ILR L H Sbjct 23 KTLGHGSFAKVKLALHV----ATGHKVAIKILNRSKIKNMGIEIKV--QREIKILRFLMH 76 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLH 1015 HII+ E + + +VMEYV G L DY+ + + + QQI G+ Y H Sbjct 77 PHIIRQYEVIETPND--IYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCH 134 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRDL NVLLD+ +KI DFGL+ + +GH ++ SP + APE + Sbjct 135 RNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGH---FLKTSCGSPNY-AAPEVISG 190 Query 1076 YKFYYASDVWSFGVTLYELL 1095 + D+WS GV LY LL Sbjct 191 KPYGPDVDIWSCGVILYALL 210 >sp|Q9LV48|PERK1_ARATH Proline-rich receptor-like protein kinase PERK1 OS=Arabidopsis thaliana OX=3702 GN=PERK1 PE=1 SV=1 Length=652 Score = 92.8 bits (229), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 72/201 (36%), Positives = 103/201 (51%), Gaps = 18/201 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V +G+ VAVK LKA G R ++ E++I+ ++H H++ Sbjct 286 LGQGGFGYVHKGILP-----SGKEVAVKQLKAGSGQGERE-FQAEVEIISRVHHRHLVSL 339 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 G C G + L LV E+VP +L +L R ++ + L A +G++YLH Sbjct 340 IGYCM-AGVQRL-LVYEFVPNNNLEFHLHGKGRPTMEWSTRLKIALGSAKGLSYLHEDCN 397 Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075 IHRD+ A N+L+D K+ DFGLAK + + + R G F Y APE Sbjct 398 PKIIHRDIKASNILIDFKFEAKVADFGLAKIASDTNTHVSTRVMG---TFGYLAPEYAAS 454 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 K SDV+SFGV L EL+T Sbjct 455 GKLTEKSDVFSFGVVLLELIT 475 Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 49/183 (27%), Positives = 79/183 (43%), Gaps = 27/183 (15%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F ++S+V H HL + G C+ G + ++V E+V + L+ L +G M W ++ Sbjct 321 FQAEVEIISRVHHRHLVSLIGYCMAGVQRLLVYEFVPNNNLEFHL-HGKGRPTMEWSTRL 379 Query 713 VVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 +A A LSYL N ++H ++ NIL+ A K++D G+ A Sbjct 380 KIALGSAKGLSYLHEDCNPKIIHRDIKASNILIDFKFEA-------KVADFGLAKIASDT 432 Query 770 EERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 V +LAPE G L+ D + FG LLE+ + R P + Sbjct 433 NTHVSTRVMGTFGYLAPEYAASG--KLTEKSDVFSFGVVLLEL-------ITGRRPVDAN 483 Query 825 HFY 827 + Y Sbjct 484 NVY 486 >sp|O74456|PEF1_SCHPO Serine/threonine-protein kinase pef1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=pef1 PE=3 SV=2 Length=288 Score = 89.0 bits (219), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 60/205 (29%), Positives = 105/205 (51%), Gaps = 17/205 (8%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +++ LGEG + V Y N TGE+VA+K ++ D S +EI +++ L H Sbjct 4 QRLEKLGEGTYAHV----YKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELRHP 59 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----SIGLAQLLLFAQQICEGMAY 1013 +I+ Q E L LV EY+ L+ Y+ + ++ +Q+ F QQ+ +G+++ Sbjct 60 NIMSLSDVL--QTENKLMLVFEYME-KDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISF 116 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072 H +HRDL +N+L+++ +K+ DFGLA+++ + + WY AP+ Sbjct 117 CHENRVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTF----SNEVVTLWYRAPDV 172 Query 1073 LKEYKFYYAS-DVWSFGVTLYELLT 1096 L + Y S D+WS G + E+ T Sbjct 173 LLGSRVYSTSIDIWSVGCIMAEMAT 197 Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust. Identities = 54/227 (24%), Positives = 97/227 (43%), Gaps = 44/227 (19%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV--LDPSH 648 +L LG+GT +VY+G+ RV G V LKV +D Sbjct 5 RLEKLGEGTYAHVYKGQNRVTGE------------------------IVALKVIRIDADE 40 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP---LDVWLRRERGH 705 + A E SLM ++ H ++ + V + ++V EY+E +D + +G Sbjct 41 GTPSTAIREI-SLMKELRHPNIMSLSDVLQTENKLMLVFEYMEKDLKKYMDTY--GNQGA 97 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG---- 761 +P + QQL +S+ ++H ++ +N+L+ G +KL+D G Sbjct 98 LPPSQVKNFTQQLLKGISFCHENRVLHRDLKPQNLLINSRGE-------LKLADFGLARS 150 Query 762 VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 +G+ + V + + AP+ L G+ ST++D W G + E+ Sbjct 151 IGIPVNTFSNEVVTLWYRAPDVLL-GSRVYSTSIDIWSVGCIMAEMA 196 >sp|Q54XJ4|Y8901_DICDI Probable serine/threonine-protein kinase DDB_G0278901 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0278901 PE=3 SV=1 Length=1495 Score = 93.6 bits (231), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 69/239 (29%), Positives = 114/239 (48%), Gaps = 22/239 (9%) Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL-LFAQ 1005 EI++L+ L H +I++Y +VME++ GSL + RH + L+ ++ Sbjct 72 EINLLKVLSHHNIVRYYEHIPSSSHS--YIVMEFIENGSLEKIIKRHGLLPESLVTVYIA 129 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 Q+ G+ YLH Q IHRD+ A N+L+ D +K+ DFG+A V + +P Sbjct 130 QVLNGLEYLHRQGVIHRDIKAANLLISTDGSIKLADFGVATKVSDLSSDNPDDTFAGTP- 188 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 +W APE ++ A DVWS G T+ ELLT +PP G+A + Sbjct 189 YWMAPEVIQMQGISTACDVWSLGCTIIELLTG-----TPP-----YFGLAPAAALYKIVQ 238 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKY-QGQAP 1181 E + P P + + NC++ + + R + + L+ P +K+V + + QAP Sbjct 239 E-----DHPPIPPGISAALKDFLLNCFKKDENIRSSAKQLLHHPWVKSVQIRNPETQAP 292 Score = 56.6 bits (135), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 45/161 (28%), Positives = 82/161 (51%), Gaps = 24/161 (15%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENI-------MVTEYVEHGPLDVWLRRERGHVPMAWKM 712 SLM++++ + H + VR E+I +V E++E+G L+ ++R G +P + Sbjct 68 SLMAEINLLKVLSHHNI-VRYYEHIPSSSHSYIVMEFIENGSLEKIIKR-HGLLPESLVT 125 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-----LGAL 767 V Q+ + L YL + ++H ++ N+L++ G IKL+D GV L + Sbjct 126 VYIAQVLNGLEYLHRQGVIHRDIKAANLLISTDG-------SIKLADFGVATKVSDLSSD 178 Query 768 SREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 + ++ P W+APE + +STA D W G T++E+ Sbjct 179 NPDDTFAGTPYWMAPEVI--QMQGISTACDVWSLGCTIIEL 217 >sp|O55076|CDK2_CRIGR Cyclin-dependent kinase 2 OS=Cricetulus griseus OX=10029 GN=CDK2 PE=1 SV=1 Length=298 Score = 89.0 bits (219), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 65/205 (32%), Positives = 102/205 (50%), Gaps = 15/205 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955 +K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ L Sbjct 4 FQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYV--PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013 H +I+K E L LV E++ L D I L + + Q+ +G+A+ Sbjct 60 HPNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASAVTGIPLPLIKSYLFQLLQGLAF 117 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072 H+ +HRDL +N+L++ + +K+ DFGLA+A Y + WY APE Sbjct 118 CHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTY----THEVVTLWYRAPEI 173 Query 1073 LKEYKFY-YASDVWSFGVTLYELLT 1096 L K+Y A D+WS G E++T Sbjct 174 LLGCKYYSTAVDIWSLGCIFAEMVT 198 Score = 37.0 bits (84), Expect = 0.91, Method: Compositional matrix adjust. Identities = 49/194 (25%), Positives = 83/194 (43%), Gaps = 46/194 (24%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREER 772 QL L++ + ++H ++ +N+L+ AEG+ IKL+D G+ G+ + Sbjct 110 QLLQGLAFCHSHRVLHRDLKPQNLLIN----AEGS---IKLADFGLARAFGVPVRTYTHE 162 Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQS------RSPS 821 V + + APE L G STA+D W G E+ F G++ + + Sbjct 163 VVTLWYRAPEIL-LGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGT 221 Query 822 EKEHFYQRQHRLPE--PSCPQLA----------------TLTSQCLTYEPTQRPSFRTIL 863 E + +P+ PS P+ A +L SQ L Y+P +R S + L Sbjct 222 PDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAAL 281 Query 864 -----RDLTRLQPH 872 +D+T+ PH Sbjct 282 AHPFFQDVTKPVPH 295 >sp|Q6P3Q4|STK4_XENTR Serine/threonine-protein kinase 4 OS=Xenopus tropicalis OX=8364 GN=stk4 PE=2 SV=1 Length=485 Score = 91.7 bits (226), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 58/197 (29%), Positives = 98/197 (50%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V Y ++ T ++VA+K + + Q +EI I++ H+ Sbjct 33 LEKLGEGSYGSV----YKASHKETSQIVAIKQIPVESDLQE---IIKEIAIMQQCDSLHV 85 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VME+ GS+ D L + ++ + Q +G+ YLH Sbjct 86 VKYYGSYFKNTD--LWIVMEFCGGGSISDIIRLRKQTLKEDETATILQSTLKGLEYLHFM 143 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+++ K+ DFG+A + + R FW APE ++E Sbjct 144 RKIHRDIKAGNILLNSEGTAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVIQEIG 200 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 201 YNCVADIWSLGITAIEM 217 Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust. Identities = 54/228 (24%), Positives = 87/228 (38%), Gaps = 21/228 (9%) Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 P D+ E A +M Q H+ +G + + +V E+ G + +R + Sbjct 62 PVESDLQEIIKEIA-IMQQCDSLHVVKYYGSYFKNTDLWIVMEFCGGGSISDIIRLRKQT 120 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763 + + Q L YL +H ++ NILL +EGT+ KL+D GV Sbjct 121 LKEDETATILQSTLKGLEYLHFMRKIHRDIKAGNILLN----SEGTA---KLADFGVAGQ 173 Query 764 -LGALSREERVERIP-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +++ V P W+APE + G N ++ D W G T +E+ +G+ P P Sbjct 174 LTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYAEIHP 229 Query 821 SEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R PE + CL P R S +L+ Sbjct 230 MRAIFMIPSNPPPTFRKPELWSKDFVDFINLCLVKNPELRSSATELLQ 277 >sp|Q8MVR1|GBPC_DICDI Cyclic GMP-binding protein C OS=Dictyostelium discoideum OX=44689 GN=gbpC PE=1 SV=1 Length=2631 Score = 93.6 bits (231), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 76/242 (31%), Positives = 120/242 (50%), Gaps = 28/242 (12%) Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLL 1001 ++ E+ + L H +++K G C + L + +EYV GSL L SI ++ L Sbjct 944 FRHEVYYMSGLNHPNVMKISGFCI----QPLCMALEYVRYGSLYSLLSNSSIEISWGLRL 999 Query 1002 LFAQQICEGMAYLHAQH--YIHRDLAARNVLLD-----NDRLVKIGDFGLAKAVPEGHEY 1054 A +I +GM +LH+ + IHRDL + N+LL+ + + I DFG + A+ G Sbjct 1000 QIASEIAKGMQHLHSHNPPVIHRDLKSPNILLNGITEGQNSVATIIDFGTSTALYGGAAL 1059 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 R D P+ W PE L + SDV+SFG+ L+EL T P +F Sbjct 1060 IRCV---DQPL-WLGPEVLAGTAYSEPSDVYSFGIILWELYTRA----HPFDEF------ 1105 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 Q + +L + + RG R P CP E L+++CW E + RPTF +++ IL + + Sbjct 1106 -QFGQWMSKLEDEIIRGLRPTIPPTCPPEYVELIQSCWTHEPNSRPTFTSIVEILGQIKK 1164 Query 1175 KY 1176 K+ Sbjct 1165 KF 1166 Score = 67.4 bits (163), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 75/271 (28%), Positives = 121/271 (45%), Gaps = 39/271 (14%) Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672 +G+ E DD D L+ R L+V H++ +Y MS ++H ++ Sbjct 919 NGNGEVMVYDDPDQLIEDR---------LRVFREFRHEV---YY-----MSGLNHPNVMK 961 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--L 730 + G C++ M EYV +G L L + ++ +A ++A + +L + N + Sbjct 962 ISGFCIQPL--CMALEYVRYGSLYSLLSNSSIEISWGLRLQIASEIAKGMQHLHSHNPPV 1019 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGV-----GLGALSREERVERIPWLAPECLP 785 +H ++ NILL G+ EG + + D G G AL R V++ WL PE L Sbjct 1020 IHRDLKSPNILLN--GITEGQNSVATIIDFGTSTALYGGAALIR--CVDQPLWLGPEVLA 1075 Query 786 GGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP- 839 G A S D + FG L E+ FD Q S E E + +P P+CP Sbjct 1076 GTA--YSEPSDVYSFGIILWELYTRAHPFDEFQFGQWMSKLEDEIIRGLRPTIP-PTCPP 1132 Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + L C T+EP RP+F +I+ L +++ Sbjct 1133 EYVELIQSCWTHEPNSRPTFTSIVEILGQIK 1163 >sp|Q3UIZ8|MYLK3_MOUSE Myosin light chain kinase 3 OS=Mus musculus OX=10090 GN=Mylk3 PE=1 SV=1 Length=795 Score = 92.8 bits (229), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 78/244 (32%), Positives = 113/244 (46%), Gaps = 38/244 (16%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRD--------------LGEGHFGKVSLYCYDPTN 920 A+ V D A+ P F R + I+D LG G FG+V + T Sbjct 456 AEAAIVVLDDSAAPPAPFEHRVVS-IKDTLISAGYTVSQHEVLGGGRFGQV----HRCTE 510 Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 TG +A K +K + R K E++I+ L H ++I+ E + S L+MEY Sbjct 511 RSTGLALAAKIIKVK-NVKDREDVKNEVNIMNQLSHVNLIQLYDAFESK--SSFTLIMEY 567 Query 981 VPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYIHRDLAARNVLL--DNDRL 1036 V G L D + L +L +LF +QICEG+ YLH + +H DL N+L Sbjct 568 VDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQ 627 Query 1037 VKIGDFGLAKAVPEGHEYYRVRE----DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 +KI DFGLA+ Y+ RE + +P F APE + + +D+WS GV Y Sbjct 628 IKIIDFGLAR-------RYKPREKLKVNFGTPEF-LAPEVVNYEFVSFPTDMWSVGVITY 679 Query 1093 ELLT 1096 LL+ Sbjct 680 MLLS 683 Score = 35.0 bits (79), Expect = 5.7, Method: Compositional matrix adjust. Identities = 38/170 (22%), Positives = 72/170 (42%), Gaps = 11/170 (6%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 ++M+Q+SH +L ++ ++ EYV+ G L + E+ H+ ++ +Q+ Sbjct 538 NIMNQLSHVNLIQLYDAFESKSSFTLIMEYVDGGELFDRITDEKYHLTELDVVLFTRQIC 597 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776 + YL ++H ++ NIL T IK+ D G+ RE+ Sbjct 598 EGVHYLHQHYILHLDLKPENIL-----CVSQTGHQIKIIDFGLARRYKPREKLKVNFGTP 652 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 +LAPE + +S D W G + + G +P + +E +F Sbjct 653 EFLAPEVV--NYEFVSFPTDMWSVG-VITYMLLSGLSPFLGETDAETMNF 699 >sp|A8XJW8|CST1_CAEBR Serine/threonine-protein kinase cst-1 OS=Caenorhabditis briggsae OX=6238 GN=cst-1 PE=3 SV=2 Length=494 Score = 91.7 bits (226), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 57/194 (29%), Positives = 97/194 (50%), Gaps = 14/194 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG +G V + + +G ++A+K + D Q +EI I++ ++++KY Sbjct 41 LGEGSYGSV----HKAIHKESGHVLAIKKVPVDTDLQE---IIKEISIMQQCKSKYVVKY 93 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G + L +VMEY GS+ D + R + ++ + +G+ YLH I Sbjct 94 YGSYFKNSD--LWIVMEYCGAGSISDIMRARRKPLSEKEISAVLRDTLKGLQYLHDLKKI 151 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ A N+LL+ D + K+ DFG+A + + R FW APE ++E + Sbjct 152 HRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIEEIGYDT 208 Query 1081 ASDVWSFGVTLYEL 1094 +D+WS G+T E+ Sbjct 209 KADIWSLGITAIEM 222 Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust. Identities = 50/213 (23%), Positives = 81/213 (38%), Gaps = 21/213 (10%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q ++ +G + + +V EY G + +R R + V + Sbjct 80 SIMQQCKSKYVVKYYGSYFKNSDLWIVMEYCGAGSISDIMRARRKPLSEKEISAVLRDTL 139 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL + +H ++ NILL G+A KL+D GV +++ V Sbjct 140 KGLQYLHDLKKIHRDIKAGNILLNTDGIA-------KLADFGVAGQLTDTMAKRNTVIGT 192 Query 777 P-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ----H 831 P W+APE + T D W G T +E+ +G P P + Sbjct 193 PFWMAPEVIE--EIGYDTKADIWSLGITAIEMA-EGRPPYSDIHPMRAIFMIPTKPPPTF 249 Query 832 RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + PE + CL +P +R +T LR Sbjct 250 KKPEEWSSEFNDFIRCCLIKKPEER---KTALR 279 >sp|P50527|STE20_SCHPO Serine/threonine-protein kinase shk1/pak1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=shk1 PE=1 SV=2 Length=658 Score = 92.4 bits (228), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 67/280 (24%), Positives = 133/280 (48%), Gaps = 15/280 (5%) Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 Q+ S SE +H + + P + +T T + + PS + + R Q ++ A Sbjct 310 QTLSTSETKHI-RPNNSTPYQRRAETSTKPKAVATPQKVEAPSAPRLQKRAPRQQSNDSA 368 Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935 + + +PT+ ++ ++K +G+G G V Y GT VA+K + + Sbjct 369 VLAKLQSICNPKNPTLLYRNFVK----IGQGASGDV----YSARQVGTNLSVAIKKMNIN 420 Query 936 CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI 995 P+ + EI ++++ +H++I+ + + E L +VMEY+ GSL + + +++ Sbjct 421 QQPK-KEFIVNEILVMKSHHHKNIVNFIDTFFYKSE--LWMVMEYMRGGSLTEVVTNNTL 477 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 Q+ ++ EG+ +LH +HRD+ + N+LL +K+ DFG + + + Sbjct 478 SEGQIAAICKETLEGLQHLHENGIVHRDIKSDNILLSLQGDIKLTDFGFCAQI-DSNMTK 536 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 R G +W APE + ++ + DVWS G+ E++ Sbjct 537 RTTMVGTP--YWMAPEVVTRKEYGFKVDVWSLGIMAIEMV 574 Score = 42.0 bits (97), Expect = 0.038, Method: Compositional matrix adjust. Identities = 58/245 (24%), Positives = 92/245 (38%), Gaps = 24/245 (10%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 R G L V +K ++ + +M H ++ E MV EY Sbjct 403 ARQVGTNLSVAIKKMNINQQPKKEFIVNEILVMKSHHHKNIVNFIDTFFYKSELWMVMEY 462 Query 690 VEHGPL-DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + G L +V +A + ++ L +L +VH ++ NILL+ G Sbjct 463 MRGGSLTEVVTNNTLSEGQIA---AICKETLEGLQHLHENGIVHRDIKSDNILLSLQG-- 517 Query 749 EGTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 IKL+D G + R V W+APE + +D W G Sbjct 518 -----DIKLTDFGFCAQIDSNMTKRTTMVGTPYWMAPEVV--TRKEYGFKVDVWSLGIMA 570 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT-----LTSQCLTYEPTQRPSF 859 +E+ +GE P + +P + P+ S P+L + S+ LT P QRPS Sbjct 571 IEMV-EGEPPYLNENPLRALYLIATIG-TPKISRPELLSSVFHDFLSKSLTVNPKQRPSS 628 Query 860 RTILR 864 +LR Sbjct 629 GELLR 633 >sp|P14056|ARAF_RAT Serine/threonine-protein kinase A-Raf OS=Rattus norvegicus OX=10116 GN=Araf PE=1 SV=1 Length=604 Score = 92.4 bits (228), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 70/257 (27%), Positives = 118/257 (46%), Gaps = 34/257 (13%) Query 927 VAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 VAVK LK A + +K E+ +LR H +I+ + G G ++ ++ S Sbjct 331 VAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG---FAIITQWCEGSS 387 Query 986 LRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 L +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L VKIGDFG Sbjct 388 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFG 447 Query 1044 LAKAVPEGHEYYRVREDGDSP-------VFWYAPECLKEYK---FYYASDVWSFGVTLYE 1093 LA + R G P V W A E ++ + + SDV+++GV LYE Sbjct 448 LATV--------KTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYE 499 Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 L+T ++ + + +G ++ L+++ CP + L+ +C + Sbjct 500 LMTGSLPYSHIGSRDQIIFMVGRGYLSP-DLSKIFS---------NCPKAMRRLLTDCLK 549 Query 1154 TEASFRPTFENLIPILK 1170 + RP F ++ ++ Sbjct 550 FQREERPLFPQILATIE 566 Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 67/255 (26%), Positives = 106/255 (42%), Gaps = 24/255 (9%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 GR G VLKV P+ A AF ++ + H ++ G R P ++T++ Sbjct 325 GRWHGDVAVKVLKVAQPTAEQ-AQAFKNEMQVLRKTRHVNILLFMGFMTR-PGFAIITQW 382 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 E L L M + VA+Q A + YL KN++H ++ NI L E Sbjct 383 CEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIF-----LHE 437 Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802 G + +K+ D G+ GA E+ + W+A E + N S D + +G Sbjct 438 GLT--VKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 495 Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855 L E+ G P ++ F R + P+ S CP+ + L + CL ++ + Sbjct 496 VLYEL-MTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRRLLTDCLKFQREE 554 Query 856 RPSFRTILRDLTRLQ 870 RP F IL + LQ Sbjct 555 RPLFPQILATIELLQ 569 >sp|O08678|MARK1_RAT Serine/threonine-protein kinase MARK1 OS=Rattus norvegicus OX=10116 GN=Mark1 PE=1 SV=1 Length=793 Score = 92.8 bits (229), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 69/199 (35%), Positives = 99/199 (50%), Gaps = 13/199 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G+G+F KV L + T G VAVK + K P +E+ I++ L H +I Sbjct 64 KTIGKGNFAKVKLARHVLT----GREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQH 1018 +K E EK+L LVMEY G + DYL H + + +QI + Y H + Sbjct 120 VKLFEVIET--EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKC 177 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRDL A N+LLD D +KI DFG + G++ G P + APE + K+ Sbjct 178 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTF--CGSPP--YAAPELFQGKKY 233 Query 1079 YYAS-DVWSFGVTLYELLT 1096 DVWS GV LY L++ Sbjct 234 DGPEVDVWSLGVILYTLVS 252 >sp|O01700|DLK1_CAEEL Mitogen-activated protein kinase kinase kinase dlk-1 OS=Caenorhabditis elegans OX=6239 GN=dlk-1 PE=1 SV=4 Length=928 Score = 93.2 bits (230), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 71/223 (32%), Positives = 107/223 (48%), Gaps = 26/223 (12%) Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQ 1005 EI LR L H++II++ G C +VMEY G L L R++I + + Sbjct 171 EIKHLRHLRHQNIIEFLGVCSKS--PCYCIVMEYCSKGQLCTVLKSRNTITRELFAQWVK 228 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS-- 1063 +I +GM YLH IHRDL + N+L+ + +KI DFG + H ++ S Sbjct 229 EIADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTS------HMQKKMDSTMMSFC 282 Query 1064 -PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 V W APE +K+ DV+SFGV L+E+LT ++P IAQ + Sbjct 283 GTVSWMAPEMIKKQPCNEKVDVYSFGVVLWEMLTR----ETP------YANIAQMAIIFG 332 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 T +L LP P++ P + L+K C + RP+F ++ Sbjct 333 VGTNILS----LPMPEEAPKGLVLLIKQCLSQKGRNRPSFSHI 371 Score = 40.8 bits (94), Expect = 0.083, Method: Compositional matrix adjust. Identities = 49/215 (23%), Positives = 86/215 (40%), Gaps = 22/215 (10%) Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726 H ++ GVC + P +V EY G L L + R + +++A + YL Sbjct 180 HQNIIEFLGVCSKSPCYCIVMEYCSKGQLCTVL-KSRNTITRELFAQWVKEIADGMHYLH 238 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER----IPWLAPE 782 ++H ++ NIL++ AE + IK+ D G + + + W+APE Sbjct 239 QNKVIHRDLKSPNILIS----AEDS---IKICDFGTSHMQKKMDSTMMSFCGTVSWMAPE 291 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-----LPEPS 837 + + +D + FG L E+ E P + ++ + +PE + Sbjct 292 MIK--KQPCNEKVDVYSFGVVLWEM-LTRETPYA--NIAQMAIIFGVGTNILSLPMPEEA 346 Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 L L QCL+ + RPSF I + +P Sbjct 347 PKGLVLLIKQCLSQKGRNRPSFSHIRQHWEIFKPE 381 >sp|Q54JQ1|MKCC_DICDI Probable serine/threonine-protein kinase mkcC OS=Dictyostelium discoideum OX=44689 GN=mkcC PE=3 SV=1 Length=891 Score = 93.2 bits (230), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 74/275 (27%), Positives = 126/275 (46%), Gaps = 30/275 (11%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 K+ K ++ +G G FG S++ T D +A+K + R+ EI L Sbjct 613 KKLYKNLKQIGSGGFG--SVFLAKSTVDKCE--IAIKKIAHVSAKAQRTNL-NEIGFLNF 667 Query 954 LYHEHIIKY--KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011 H +I+ Y +D ++ + MEY+ G+L + H+ + + A+ + EG+ Sbjct 668 CKHPNIVSYLRSHLVDD----TIWIAMEYMQGGTLTEASQGHTFNESCIAYVAKGMLEGL 723 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 YLHA + +HRD+ + N+++ D +KI DFGL + +E V G SP FW +PE Sbjct 724 MYLHAHNIVHRDIKSGNIMMTIDGKIKIVDFGLC---VDANERKLVHMAG-SP-FWMSPE 778 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 ++ + +D+WSF + L EL ++ PP + L + T E Sbjct 779 MIRGESYGCPTDIWSFAICLLEL-----ANGEPPHRKSSLTAM---------FTTATEGC 824 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L +P++ H + C E + S R T E L+ Sbjct 825 AGLDKPERWTEHFTHFLNLCLEMDPSKRSTAEQLL 859 Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust. Identities = 48/188 (26%), Positives = 77/188 (41%), Gaps = 23/188 (12%) Query 685 MVTEYVEHGPLDVWLRRERGHV-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 + EY++ G L +GH + VA+ + L YL N+VH ++ NI++ Sbjct 688 IAMEYMQGGTL---TEASQGHTFNESCIAYVAKGMLEGLMYLHAHNIVHRDIKSGNIMMT 744 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSRE-ERVERIP-WLAPECLPGGANSLSTAMDKWGFG 801 G IK+ D G+ + A R+ + P W++PE + G S D W F Sbjct 745 IDGK-------IKIVDFGLCVDANERKLVHMAGSPFWMSPEMIRG--ESYGCPTDIWSFA 795 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQH-----RLPEPSCPQLATLTSQCLTYEPTQR 856 LLE+ +GE P R S F PE + CL +P++R Sbjct 796 ICLLELA-NGEPP--HRKSSLTAMFTTATEGCAGLDKPERWTEHFTHFLNLCLEMDPSKR 852 Query 857 PSFRTILR 864 + +L+ Sbjct 853 STAEQLLK 860 >sp|Q8VHJ5|MARK1_MOUSE Serine/threonine-protein kinase MARK1 OS=Mus musculus OX=10090 GN=Mark1 PE=1 SV=2 Length=795 Score = 92.8 bits (229), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 69/199 (35%), Positives = 99/199 (50%), Gaps = 13/199 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G+G+F KV L + T G VAVK + K P +E+ I++ L H +I Sbjct 64 KTIGKGNFAKVKLARHVLT----GREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQH 1018 +K E EK+L LVMEY G + DYL H + + +QI + Y H + Sbjct 120 VKLFEVIET--EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKC 177 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRDL A N+LLD D +KI DFG + G++ G P + APE + K+ Sbjct 178 IVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTF--CGSPP--YAAPELFQGKKY 233 Query 1079 YYAS-DVWSFGVTLYELLT 1096 DVWS GV LY L++ Sbjct 234 DGPEVDVWSLGVILYTLVS 252 Score = 34.7 bits (78), Expect = 7.4, Method: Compositional matrix adjust. Identities = 51/236 (22%), Positives = 93/236 (39%), Gaps = 22/236 (9%) Query 639 VVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K++D + + + +M ++H ++ + V +V EY G + Sbjct 86 VAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVF 145 Query 697 VWLRRERGHVPMAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 +L H M K A+ Q+ SA+ Y K +VH ++ N+LL Sbjct 146 DYLV---AHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLL-------DADMN 195 Query 755 IKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 IK++D G + +++ P+ APE G +D W G L + Sbjct 196 IKIADFGFS-NEFTVGNKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLV-S 252 Query 811 GEAPLQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 G P ++ E +E + ++R+P L + L P +R S I++D Sbjct 253 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKD 308 >sp|P04627|ARAF_MOUSE Serine/threonine-protein kinase A-Raf OS=Mus musculus OX=10090 GN=Araf PE=1 SV=2 Length=604 Score = 92.4 bits (228), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 70/257 (27%), Positives = 118/257 (46%), Gaps = 34/257 (13%) Query 927 VAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 VAVK LK A + +K E+ +LR H +I+ + G G ++ ++ S Sbjct 331 VAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG---FAIITQWCEGSS 387 Query 986 LRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 L +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L VKIGDFG Sbjct 388 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFG 447 Query 1044 LAKAVPEGHEYYRVREDGDSP-------VFWYAPECLKEYK---FYYASDVWSFGVTLYE 1093 LA + R G P V W A E ++ + + SDV+++GV LYE Sbjct 448 LATV--------KTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYE 499 Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 L+T ++ + + +G ++ L+++ CP + L+ +C + Sbjct 500 LMTGSLPYSHIGSRDQIIFMVGRGYLSP-DLSKIFS---------NCPKAMRRLLTDCLK 549 Query 1154 TEASFRPTFENLIPILK 1170 + RP F ++ ++ Sbjct 550 FQREERPLFPQILATIE 566 Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 67/255 (26%), Positives = 106/255 (42%), Gaps = 24/255 (9%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 GR G VLKV P+ A AF ++ + H ++ G R P ++T++ Sbjct 325 GRWHGDVAVKVLKVAQPTAEQ-AQAFKNEMQVLRKTRHVNILLFMGFMTR-PGFAIITQW 382 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 E L L M + VA+Q A + YL KN++H ++ NI L E Sbjct 383 CEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIF-----LHE 437 Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802 G + +K+ D G+ GA E+ + W+A E + N S D + +G Sbjct 438 GLT--VKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 495 Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855 L E+ G P ++ F R + P+ S CP+ + L + CL ++ + Sbjct 496 VLYEL-MTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRRLLTDCLKFQREE 554 Query 856 RPSFRTILRDLTRLQ 870 RP F IL + LQ Sbjct 555 RPLFPQILATIELLQ 569 >sp|Q6PA14|STK4_XENLA Serine/threonine-protein kinase 4 OS=Xenopus laevis OX=8355 GN=stk4 PE=2 SV=1 Length=485 Score = 91.7 bits (226), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V Y ++ T ++VA+K + + Q +EI I++ H+ Sbjct 33 LEKLGEGSYGSV----YKASHKETSQIVAIKQIPVESDLQE---IIKEISIMQQCDSPHV 85 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VME+ GS+ D L + ++ ++ Q +G+ YLH Sbjct 86 VKYYGSYFKNTD--LWIVMEFCGGGSVSDIIRLRKQTLNEDEIATILQSTLKGLEYLHFM 143 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL + K+ DFG+A + + R FW APE ++E Sbjct 144 RKIHRDIKAGNILLSCEGTAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVIQEIG 200 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 201 YNCVADIWSLGITAIEM 217 Score = 43.5 bits (101), Expect = 0.012, Method: Compositional matrix adjust. Identities = 51/214 (24%), Positives = 83/214 (39%), Gaps = 20/214 (9%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q H+ +G + + +V E+ G + +R + + + Q Sbjct 75 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEFCGGGSVSDIIRLRKQTLNEDEIATILQSTL 134 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL +H ++ NILL+ EGT+ KL+D GV +++ V Sbjct 135 KGLEYLHFMRKIHRDIKAGNILLS----CEGTA---KLADFGVAGQLTDTMAKRNTVIGT 187 Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830 P W+APE + G N ++ D W G T +E+ +G+ P P Sbjct 188 PFWMAPEVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYAEIHPMRAIFMIPSNPPPT 243 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R PE + CL P R S +L+ Sbjct 244 FRKPELWSKDFVDFINLCLVKNPELRSSATELLQ 277 >sp|Q9LT96|Y5977_ARATH Probable leucine-rich repeat receptor-like protein kinase At5g49770 OS=Arabidopsis thaliana OX=3702 GN=At5g49770 PE=1 SV=1 Length=946 Score = 93.2 bits (230), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 82/262 (31%), Positives = 129/262 (49%), Gaps = 21/262 (8%) Query 923 TGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 G+++A+K +A G Q +K EI++L ++H++++K G C DQ E+ LV EY+ Sbjct 655 NGQVIAIK--RAQQGSMQGAFEFKTEIELLSRVHHKNVVKLLGFCFDQKEQ--MLVYEYI 710 Query 982 PLGSLRDYLP-RHSIGL--AQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDR 1035 P GSLRD L ++ + L + L A +G+AYLH IHRD+ + N+LLD Sbjct 711 PNGSLRDGLSGKNGVKLDWTRRLKIALGSGKGLAYLHELADPPIIHRDVKSNNILLDEHL 770 Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 K+ DFGL+K V + E V + + PE + SDV+ FGV + ELL Sbjct 771 TAKVADFGLSKLVGD-PEKAHVTTQVKGTMGYLDPEYYMTNQLTEKSDVYGFGVVMLELL 829 Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLR----LTELLERGERLPRPDKCPCEVY-HLMKN 1150 T +SP + ++ + +M R L ELL+ + E Y + Sbjct 830 T----GKSPIDRGSYVVKEVKKKMDKSRNLYDLQELLDTTIIQNSGNLKGFEKYVDVALQ 885 Query 1151 CWETEASFRPTFENLIPILKTV 1172 C E E RPT ++ L+++ Sbjct 886 CVEPEGVNRPTMSEVVQELESI 907 Score = 49.3 bits (116), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 59/244 (24%), Positives = 100/244 (41%), Gaps = 40/244 (16%) Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW- 710 A F L+S+V H ++ + G C E ++V EY+ +G L L + G V + W Sbjct 672 AFEFKTEIELLSRVHHKNVVKLLGFCFDQKEQMLVYEYIPNGSLRDGLSGKNG-VKLDWT 730 Query 711 -KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--L 764 ++ +A L+YL + ++H +V NILL A K++D G+ + Sbjct 731 RRLKIALGSGKGLAYLHELADPPIIHRDVKSNNILLDEHLTA-------KVADFGLSKLV 783 Query 765 GALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 G + ++ +L PE N L+ D +GFG +LE+ G++P+ S Sbjct 784 GDPEKAHVTTQVKGTMGYLDPEYYM--TNQLTEKSDVYGFGVVMLEL-LTGKSPIDRGSY 840 Query 821 SEKE---------HFYQRQHRLPEPSCPQLATLTS---------QCLTYEPTQRPSFRTI 862 KE + Y Q L L QC+ E RP+ + Sbjct 841 VVKEVKKKMDKSRNLYDLQELLDTTIIQNSGNLKGFEKYVDVALQCVEPEGVNRPTMSEV 900 Query 863 LRDL 866 +++L Sbjct 901 VQEL 904 >sp|Q9ASQ6|Y1972_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g29720 OS=Arabidopsis thaliana OX=3702 GN=RFK1 PE=2 SV=3 Length=1019 Score = 93.2 bits (230), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 85/280 (30%), Positives = 136/280 (49%), Gaps = 27/280 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG V +DGT ++AVK L + +R + EI ++ L H +++K Sbjct 679 LGEGGFGSV---FKGELSDGT--IIAVKQLSSKSSQGNRE-FVNEIGMISGLNHPNLVKL 732 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA----YLH-- 1015 GCC ++ + L LV EY+ SL L ++S+ L Q+IC G+A +LH Sbjct 733 YGCCVERDQ--LLLVYEYMENNSLALALFGQNSLKLDWAA--RQKICVGIARGLEFLHDG 788 Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 A +HRD+ NVLLD D KI DFGLA+ H + + G + + APE Sbjct 789 SAMRMVHRDIKTTNVLLDTDLNAKISDFGLARLHEAEHTHISTKVAG--TIGYMAPEYAL 846 Query 1075 EYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + +DV+SFGV E+++ ++ Q + LI A +T+ + ++LE +R Sbjct 847 WGQLTEKADVYSFGVVAMEIVSGKSNTKQQGNADSVSLINWA---LTLQQTGDILEIVDR 903 Query 1134 LPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170 + + E ++K C + S RPT + +L+ Sbjct 904 MLEGEFNRSEAVRMIKVALVCTNSSPSLRPTMSEAVKMLE 943 Score = 38.5 bits (88), Expect = 0.44, Method: Compositional matrix adjust. Identities = 41/164 (25%), Positives = 72/164 (44%), Gaps = 22/164 (13%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMV 713 F ++S ++H +L ++G CV + ++V EY+E+ L + L + + A + Sbjct 714 FVNEIGMISGLNHPNLVKLYGCCVERDQLLLVYEYMENNSLALALFGQNSLKLDWAARQK 773 Query 714 VAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + +A L +L + + +VH ++ N+LL T K+SD GL L Sbjct 774 ICVGIARGLEFLHDGSAMRMVHRDIKTTNVLL-------DTDLNAKISD--FGLARLHEA 824 Query 771 ERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 E I ++APE G L+ D + FG +EI Sbjct 825 EHTHISTKVAGTIGYMAPEYALWG--QLTEKADVYSFGVVAMEI 866 >sp|Q9LX66|HERK_ARATH Receptor-like protein kinase HERK 1 OS=Arabidopsis thaliana OX=3702 GN=HERK1 PE=1 SV=1 Length=830 Score = 92.8 bits (229), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 75/230 (33%), Positives = 118/230 (51%), Gaps = 27/230 (12%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHE 957 R++G G FGKV NDGT VAVK P+ + G ++ EI++L H Sbjct 489 RNIGVGGFGKV---YKGELNDGT--KVAVKR----GNPKSQQGLAEFRTEIEMLSQFRHR 539 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ-QICEGMA---- 1012 H++ G C++ E + L+ EY+ G+++ +L + GL L + +IC G A Sbjct 540 HLVSLIGYCDENNE--MILIYEYMENGTVKSHL--YGSGLPSLTWKQRLEICIGAARGLH 595 Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH ++ IHRD+ + N+LLD + + K+ DFGL+K PE + + V + Sbjct 596 YLHTGDSKPVIHRDVKSANILLDENFMAKVADFGLSKTGPELDQTH-VSTAVKGSFGYLD 654 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 PE + + SDV+SFGV L+E+L C PT E++ +A+ M Sbjct 655 PEYFRRQQLTDKSDVYSFGVVLFEVL--CARPVIDPTLPREMVNLAEWAM 702 Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust. Identities = 61/252 (24%), Positives = 99/252 (39%), Gaps = 28/252 (11%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K +P F ++SQ H HL + G C E I++ EY+E+G + Sbjct 509 KVAVKRGNPKSQQGLAEFRTEIEMLSQFRHRHLVSLIGYCDENNEMILIYEYMENGTVKS 568 Query 698 WLRRERGHVPMAWK--MVVAQQLASALSYL---ENKNLVHGNVCGRNILLARLGLAEGTS 752 L G + WK + + A L YL ++K ++H +V NILL +A+ Sbjct 569 HLYGS-GLPSLTWKQRLEICIGAARGLHYLHTGDSKPVIHRDVKSANILLDENFMAKVAD 627 Query 753 PFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI---- 807 LS G L V+ +L PE L+ D + FG L E+ Sbjct 628 --FGLSKTGPELDQTHVSTAVKGSFGYLDPEYFR--RQQLTDKSDVYSFGVVLFEVLCAR 683 Query 808 -CFDGEAPLQSRSPSEKEHFYQRQHRLPE------------PSCPQLATLTSQCLTYEPT 854 D P + + +E +Q++ +L + S + A +CL Sbjct 684 PVIDPTLPREMVNLAEWAMKWQKKGQLDQIIDQSLRGNIRPDSLRKFAETGEKCLADYGV 743 Query 855 QRPSFRTILRDL 866 RPS +L +L Sbjct 744 DRPSMGDVLWNL 755 >sp|P43450|CDK2_CARAU Cyclin-dependent kinase 2 OS=Carassius auratus OX=7957 GN=cdk2 PE=1 SV=1 Length=298 Score = 89.0 bits (219), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 65/205 (32%), Positives = 100/205 (49%), Gaps = 15/205 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955 +K+ +GEG +G V Y N TGE VA+K ++ D + S +EI +L+ L Sbjct 4 FQKVEKIGEGTYGVV----YKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELN 59 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYV--PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013 H +I+K E L LV E++ L D I L + + Q+ +G+A+ Sbjct 60 HPNIVKLHDVI--HTENKLYLVFEFLHQDLKRFMDSSTVTGISLPLVKSYLFQLLQGLAF 117 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072 H+ +HRDL +N+L++ +K+ DFGLA+A Y + WY APE Sbjct 118 CHSHRVLHRDLKPQNLLINAQGEIKLADFGLARAFGVPVRTY----THEVVTLWYRAPEI 173 Query 1073 LKEYKFY-YASDVWSFGVTLYELLT 1096 L K+Y A D+WS G E++T Sbjct 174 LLGCKYYSTAVDIWSLGCIFAEMIT 198 Score = 34.7 bits (78), Expect = 5.3, Method: Compositional matrix adjust. Identities = 68/328 (21%), Positives = 127/328 (39%), Gaps = 62/328 (19%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDP-EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 ++ +G+GT VY+ + +V G ++ ++D E VP Sbjct 6 KVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVP-------------------- 45 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 + A E SL+ +++H ++ +H V + +V E++ + + Sbjct 46 --STAIREI-SLLKELNHPNIVKLHDVIHTENKLYLVFEFLHQDLKRFMDSSTVTGISLP 102 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLG 765 QL L++ + ++H ++ +N+L+ A+G IKL+D G+ G+ Sbjct 103 LVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLIN----AQGE---IKLADFGLARAFGVP 155 Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQSRSP 820 + V + + APE L G STA+D W G E+ F G+ Sbjct 156 VRTYTHEVVTLWYRAPEILLG-CKYYSTAVDIWSLGCIFAEMITRKALFPGD-------- 206 Query 821 SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR-DLTRLQP-------H 872 SE + ++ L P +TS P +PSF R DL+++ P Sbjct 207 SEIDQLFRIFRTLGTPDESIWPGVTSM-----PDYKPSFPKWARQDLSKVVPPLDEDGRD 261 Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKI 900 L +L +P+ S R+ + + Sbjct 262 LLGQMLIYDPNKRISAKNALVHRFFRDV 289 >sp|P51954|NEK1_MOUSE Serine/threonine-protein kinase Nek1 OS=Mus musculus OX=10090 GN=Nek1 PE=1 SV=2 Length=1203 Score = 93.2 bits (230), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 58/201 (29%), Positives = 102/201 (51%), Gaps = 11/201 (5%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 +++ +GEG FGK L T DG ++ + + + R ++E+ +L + H + Sbjct 6 RLQKIGEGSFGKAVLV--KSTEDGRHYVIKEINI-SRMSDKERQESRREVAVLANMKHPN 62 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLH 1015 I++YK E+ G SL +VM+Y G L + L Q+L + QIC + ++H Sbjct 63 IVQYKESFEENG--SLYIVMDYCEGGDLFKRINAQKGALFQEDQILDWFVQICLALKHVH 120 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + +HRD+ ++N+ L D V++GDFG+A+ + E R ++ +PE + Sbjct 121 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELART---CIGTPYYLSPEICEN 177 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 + SD+W+ G LYEL T Sbjct 178 KPYNNKSDIWALGCVLYELCT 198 >sp|B4HNW4|PTK7_DROSE Tyrosine-protein kinase-like otk OS=Drosophila sechellia OX=7238 GN=otk PE=3 SV=1 Length=1029 Score = 92.8 bits (229), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 63/259 (24%), Positives = 123/259 (47%), Gaps = 31/259 (12%) Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 G ++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY Sbjct 774 GLDQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPH--YMVLEYT 831 Query 982 PLGSLRDYLPRHS---------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 G L+ +L + + +Q+L A QI GM ++ + HRDLA Sbjct 832 DWGDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLAT 891 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RN ++ ++ +VK+ L K EY++ R + P+ W APEC++E ++ SD+++ Sbjct 892 RNCVISSEFIVKVSYPALCKD-KYSREYHKHR-NTLLPIRWLAPECIQEDEYTTKSDIFA 949 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 +GV ++EL +++ P + + + Q L + + P + Sbjct 950 YGVVVWELFNQ--ATKLPHEELTNEQVVQRSQAGSLEWS----------VAEATPDSLRE 997 Query 1147 LMKNCWETEASFRPTFENL 1165 ++ +CW + RP+F L Sbjct 998 ILLSCWVSNPKERPSFSQL 1016 Score = 55.5 bits (132), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 64/259 (25%), Positives = 103/259 (40%), Gaps = 44/259 (17%) Query 639 VVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V++K L+ + A F L+ +SH + + G+C + MV EY + G L Sbjct 779 VLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDWGDLKQ 838 Query 698 WLRRERGHVPMAWK-------------MVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 +L G V A + VA Q+A + + H ++ RN ++ Sbjct 839 FLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRNCVI-- 896 Query 745 LGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKW 798 +S FI K+S P + SRE R I WLAPEC+ + +T D + Sbjct 897 ------SSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQ--EDEYTTKSDIF 948 Query 799 GFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQH------RLPEPSCPQLATLTSQCL 849 +G + E+ F+ L P E+ E QR + E + L + C Sbjct 949 AYGVVVWEL-FNQATKL----PHEELTNEQVVQRSQAGSLEWSVAEATPDSLREILLSCW 1003 Query 850 TYEPTQRPSFRTILRDLTR 868 P +RPSF + L++ Sbjct 1004 VSNPKERPSFSQLGAALSK 1022 >sp|O70146|TESK1_MOUSE Dual specificity testis-specific protein kinase 1 OS=Mus musculus OX=10090 GN=Tesk1 PE=1 SV=3 Length=627 Score = 92.0 bits (227), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 63/199 (32%), Positives = 102/199 (51%), Gaps = 16/199 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G F +V Y + +G+++ +K K P +RS +E+ ++ L H +I+++ Sbjct 58 IGAGFFSEV----YKVRHRQSGQVMVLKMNKL---PSNRSNTLREVQLMNRLRHPNILRF 110 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G C QG+ L + EY+ G+L L + L A I +G+ YLHA+ H Sbjct 111 MGVCVHQGQ--LHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIAQGLRYLHAKGVFH 168 Query 1022 RDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVFWYAPECLKEY 1076 RDL ++N L+ D +GDFGLA+ +P E R SP +W APE L+ Sbjct 169 RDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGTRKEPLAVVGSP-YWMAPEVLRGE 227 Query 1077 KFYYASDVWSFGVTLYELL 1095 + +DV++FG+ L EL+ Sbjct 228 LYDEKADVFAFGIVLCELI 246 Score = 44.7 bits (104), Expect = 0.006, Method: Compositional matrix adjust. Identities = 63/264 (24%), Positives = 107/264 (41%), Gaps = 51/264 (19%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 R GQ + + + L PS+ L LM+++ H ++ GVCV + +TEY+ Sbjct 72 RQSGQVMVLKMNKL-PSNRSNTL---REVQLMNRLRHPNILRFMGVCVHQGQLHALTEYM 127 Query 691 EHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLAR---- 744 G L+ L P++W ++ +A +A L YL K + H ++ +N L+ R Sbjct 128 NGGTLEQLLSSPE---PLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRREDRG 184 Query 745 -------LGLAEGTSPFIKLS--DPGVGLGALSREERVERIPWLAPECLPGGANSLSTAM 795 GLAE + + + +P +G+ W+APE L G Sbjct 185 FTAVVGDFGLAEKIPVYREGTRKEPLAVVGSPY---------WMAPEVLRG--ELYDEKA 233 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---------HRLPEPSCP-QLATLT 845 D + FG L E L +R P++ ++ + + L CP L Sbjct 234 DVFAFGIVLCE--------LIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLA 285 Query 846 SQCLTYEPTQRPSFRTILRDLTRL 869 C + EP+ R F I + L ++ Sbjct 286 IHCCSMEPSTRAPFTEITQHLEQI 309 >sp|Q9QY78|IKKB_RAT Inhibitor of nuclear factor kappa-B kinase subunit beta OS=Rattus norvegicus OX=10116 GN=Ikbkb PE=1 SV=1 Length=757 Score = 92.4 bits (228), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 68/207 (33%), Positives = 100/207 (48%), Gaps = 23/207 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + N TGE +A+K + + P++R W EI I+R L H +++ Sbjct 21 LGTGGFGNVIRW----HNQVTGEQIAIKQCRQELSPKNRDRWCLEIQIMRRLNHPNVVAA 76 Query 963 KGCCEDQGEKSLQ------LVMEYVPLGSLRDYLPR--HSIGLAQ--LLLFAQQICEGMA 1012 + E G ++L L MEY G LR YL + + GL + +L I + Sbjct 77 RDVPE--GMQNLAPNDLPLLAMEYCQGGDLRRYLNQFENCCGLREGAILTLLSDIASALR 134 Query 1013 YLHAQHYIHRDLAARNVLLDN--DRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH IHRDL N++L RL+ KI D G AK + +G + + + A Sbjct 135 YLHENRIIHRDLKPENIVLQQGEKRLIHKIIDLGYAKELDQGS----LCTSFVGTLQYLA 190 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096 PE L++ K+ D WSFG +E +T Sbjct 191 PELLEQQKYTVTVDYWSFGTLAFECIT 217 >sp|Q60855|RIPK1_MOUSE Receptor-interacting serine/threonine-protein kinase 1 OS=Mus musculus OX=10090 GN=Ripk1 PE=1 SV=1 Length=656 Score = 92.0 bits (227), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 79/275 (29%), Positives = 124/275 (45%), Gaps = 31/275 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 DL G FGKVSL CY ++ G ++ K ++ +E ++ L H ++K Sbjct 22 DLDSGGFGKVSL-CYHRSH---GFVILKKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVVK 77 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G ++G SL VMEY+ G+L L + L+ + EGM YLH + I Sbjct 78 LLGIIIEEGNYSL--VMEYMEKGNLMHVLKTQIDVPLSLKGRIIVEAIEGMCYLHDKGVI 135 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLA------KAVPEGHEYYR-----VREDGDSPVFWYA 1069 H+DL N+L+D D +KI D G+A K E + +++ +++ A Sbjct 136 HKDLKPENILVDRDFHIKIADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMA 195 Query 1070 PECLKEY--KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 PE L + K SDV+SFG+ L+ + + ++ +I I G + E+ Sbjct 196 PEHLNDINAKPTEKSDVYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNRP--NVEEI 253 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 LE CP E+ LM+ CW+ RPTF Sbjct 254 LEY---------CPREIISLMERCWQAIPEDRPTF 279 Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 57/284 (20%), Positives = 117/284 (41%), Gaps = 40/284 (14%) Query 639 VVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V+LK + P+ + E +M ++ H+ + + G+ + +V EY+E G L Sbjct 42 VILKKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVVKLLGIIIEEGNYSLVMEYMEKGNL- 100 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 + + + + VP++ K + + + YL +K ++H ++ NIL+ R IK Sbjct 101 MHVLKTQIDVPLSLKGRIIVEAIEGMCYLHDKGVIHKDLKPENILVDR-------DFHIK 153 Query 757 LSDPGVG------------------LGALSREERVERIPWLAPECLPGGANSLSTAMDKW 798 ++D GV + + +++ + ++APE L + D + Sbjct 154 IADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMAPEHLNDINAKPTEKSDVY 213 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-----CP-QLATLTSQCLTYE 852 FG L I F + P ++ +E+ + P CP ++ +L +C Sbjct 214 SFGIVLWAI-FAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPREIISLMERCWQAI 272 Query 853 PTQRPSFRTILRD-----LTRLQPHNLADVLTVNPDSPASDPTV 891 P RP+F I + L+ + + DV ++ + P P + Sbjct 273 PEDRPTFLGIEEEFRPFYLSHFEEYVEEDVASLKKEYPDQSPVL 316 >sp|Q9NB31|CST1_CAEEL Serine/threonine-protein kinase cst-1 OS=Caenorhabditis elegans OX=6239 GN=cst-1 PE=1 SV=1 Length=497 Score = 91.3 bits (225), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 57/194 (29%), Positives = 97/194 (50%), Gaps = 14/194 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG +G V + + +G ++A+K + D Q +EI I++ ++++KY Sbjct 41 LGEGSYGSV----HKAIHRESGHVLAIKKVPVDTDLQE---IIKEISIMQQCKSKYVVKY 93 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G + L +VMEY GS+ D + R + ++ + +G+ YLH I Sbjct 94 YGSYFKHSD--LWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKI 151 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ A N+LL+ D + K+ DFG+A + + R FW APE ++E + Sbjct 152 HRDIKAGNILLNTDGIAKLADFGVAGQLT---DTMAKRNTVIGTPFWMAPEVIEEIGYDT 208 Query 1081 ASDVWSFGVTLYEL 1094 +D+WS G+T E+ Sbjct 209 KADIWSLGITAIEM 222 Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust. Identities = 50/213 (23%), Positives = 81/213 (38%), Gaps = 21/213 (10%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q ++ +G + + +V EY G + +R R + V + Sbjct 80 SIMQQCKSKYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTL 139 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL + +H ++ NILL G+A KL+D GV +++ V Sbjct 140 KGLQYLHDLKKIHRDIKAGNILLNTDGIA-------KLADFGVAGQLTDTMAKRNTVIGT 192 Query 777 P-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ----H 831 P W+APE + T D W G T +E+ +G P P + Sbjct 193 PFWMAPEVIE--EIGYDTKADIWSLGITAIEMA-EGRPPYSDIHPMRAIFMIPTKPPPTF 249 Query 832 RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + PE + CL +P +R +T LR Sbjct 250 KKPEEWSSEFNDFIRSCLIKKPEER---KTALR 279 >sp|Q63572|TESK1_RAT Dual specificity testis-specific protein kinase 1 OS=Rattus norvegicus OX=10116 GN=Tesk1 PE=1 SV=1 Length=628 Score = 92.0 bits (227), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 63/201 (31%), Positives = 102/201 (51%), Gaps = 16/201 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G F +V Y + +G+++ +K K P +RS +E+ ++ L H +I+++ Sbjct 58 IGAGFFSEV----YKVRHRQSGQVMVLKMNKL---PSNRSNTLREVQLMNRLRHPNILRF 110 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G C QG+ L + EY+ G+L L + L A I +G+ YLHA+ H Sbjct 111 MGVCVHQGQ--LHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIAQGLRYLHAKGVFH 168 Query 1022 RDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVFWYAPECLKEY 1076 RDL ++N L+ D +GDFGLA+ +P E R SP +W APE L+ Sbjct 169 RDLTSKNCLVRREDGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSP-YWMAPEVLRGE 227 Query 1077 KFYYASDVWSFGVTLYELLTH 1097 + +DV++FG+ L EL+ Sbjct 228 LYDEKADVFAFGIVLCELIAR 248 Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust. Identities = 66/263 (25%), Positives = 104/263 (40%), Gaps = 49/263 (19%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 R GQ + + + L PS+ L LM+++ H ++ GVCV + +TEY+ Sbjct 72 RQSGQVMVLKMNKL-PSNRSNTL---REVQLMNRLRHPNILRFMGVCVHQGQLHALTEYM 127 Query 691 EHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLAR---- 744 G L+ L P++W ++ +A +A L YL K + H ++ +N L+ R Sbjct 128 NGGTLEQLLSSPE---PLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRREDGG 184 Query 745 -------LGLAEGTSPFIKLSDPGVGLGALSREERVERIP-WLAPECLPGGANSLSTAMD 796 GLAE P GA V P W+APE L G D Sbjct 185 FTAVVGDFGLAEKI--------PVYREGARKEPLAVVGSPYWMAPEVLRG--ELYDEKAD 234 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---------HRLPEPSCP-QLATLTS 846 + FG L E L +R P++ ++ + + L CP L Sbjct 235 VFAFGIVLCE--------LIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAI 286 Query 847 QCLTYEPTQRPSFRTILRDLTRL 869 C + EP+ R F I + L ++ Sbjct 287 HCCSMEPSARAPFTEITQHLEQI 309 >sp|Q2QAV0|TIO_ARATH Serine/threonine-protein kinase TIO OS=Arabidopsis thaliana OX=3702 GN=TIO PE=1 SV=1 Length=1322 Score = 92.8 bits (229), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 67/197 (34%), Positives = 102/197 (52%), Gaps = 12/197 (6%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK-ALKADCGPQHRSGWKQEIDILRTLYHEH 958 I +GEG FG+V Y TG+ VA+K +K + +QEI+ILR L HE+ Sbjct 9 IELVGEGSFGRV----YKGRRKYTGQTVAMKFIMKQGKTDKDIHSLRQEIEILRKLKHEN 64 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQ 1017 II+ E+ E +V E+ G L + L + Q+ A+Q+ + + YLH+ Sbjct 65 IIEMLDSFENARE--FCVVTEFAQ-GELFEILEDDKCLPEEQVQAIAKQLVKALDYLHSN 121 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ +N+L+ +VK+ DFG A+A+ +R +P + APE +KE Sbjct 122 RIIHRDMKPQNILIGAGSVVKLCDFGFARAMSTN--TVVLRSIKGTP-LYMAPELVKEQP 178 Query 1078 FYYASDVWSFGVTLYEL 1094 + D+WS GV LYEL Sbjct 179 YDRTVDLWSLGVILYEL 195 Score = 37.7 bits (86), Expect = 0.81, Method: Compositional matrix adjust. Identities = 44/187 (24%), Positives = 76/187 (41%), Gaps = 20/187 (11%) Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 E +VTE+ + G L L ++ +P +A+QL AL YL + ++H ++ +NIL Sbjct 77 EFCVVTEFAQ-GELFEILEDDKC-LPEEQVQAIAKQLVKALDYLHSNRIIHRDMKPQNIL 134 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP----WLAPECLPGGANSLSTAMDK 797 + G +KL D G + + I ++APE + +D Sbjct 135 I-------GAGSVVKLCDFGFARAMSTNTVVLRSIKGTPLYMAPELVK--EQPYDRTVDL 185 Query 798 WGFGATLLEICFDGEAPLQSRSP-SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 W G L E+ + G+ P + S + H + + P+ + L EP R Sbjct 186 WSLGVILYEL-YVGQPPFYTNSVYALIRHIVKDPVKYPDEMSTYFESFLKGLLNKEPHSR 244 Query 857 ---PSFR 860 P+ R Sbjct 245 LTWPALR 251 >sp|P17157|PHO85_YEAST Cyclin-dependent protein kinase PHO85 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PHO85 PE=1 SV=2 Length=305 Score = 88.6 bits (218), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 63/209 (30%), Positives = 101/209 (48%), Gaps = 20/209 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 K++ LG G + V Y N TG VA+K +K D S +EI +++ L H Sbjct 7 FKQLEKLGNGTYATV----YKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKH 62 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFAQQICE 1009 E+I++ E L LV E++ L+ Y+ ++G L + F Q+ + Sbjct 63 ENIVRLYDVI--HTENKLTLVFEFMD-NDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQ 119 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068 G+A+ H +HRDL +N+L++ +K+GDFGLA+A + + WY Sbjct 120 GLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTF----SSEVVTLWYR 175 Query 1069 APECLKEYKFYYAS-DVWSFGVTLYELLT 1096 AP+ L + Y S D+WS G L E++T Sbjct 176 APDVLMGSRTYSTSIDIWSCGCILAEMIT 204 Score = 44.7 bits (104), Expect = 0.003, Method: Compositional matrix adjust. Identities = 76/330 (23%), Positives = 131/330 (40%), Gaps = 66/330 (20%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDP-EEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + QL LG GT VY+G + G +E K+D E+ G + ++ Sbjct 6 QFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEE--------GTPSTAIREI--- 54 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 SLM ++ H ++ ++ V + +V E++++ R G+ Sbjct 55 -------------SLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNT 101 Query 707 PMAWKMVVAQ----QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 P ++ + + QL L++ ++H ++ +N+L+ + G +KL D G+ Sbjct 102 PRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQ-------LKLGDFGL 154 Query 763 ----GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 G+ + V + + AP+ L G+ + ST++D W G L E+ G+ Sbjct 155 ARAFGIPVNTFSSEVVTLWYRAPDVL-MGSRTYSTSIDIWSCGCILAEMI-TGKPLFPGT 212 Query 819 SPSEKEHFYQRQHRLPEPSC-PQLATLTSQCLTYEPT--QRPSFRTILRDLTR-LQPH-- 872 + E+ P S P + L Y P QRP RDL + LQPH Sbjct 213 NDEEQLKLIFDIMGTPNESLWPSVTKLPK----YNPNIQQRPP-----RDLRQVLQPHTK 263 Query 873 -----NLAD----VLTVNPDSPASDPTVFH 893 NL D +L +NPD S H Sbjct 264 EPLDGNLMDFLHGLLQLNPDMRLSAKQALH 293 >sp|Q69ZA1|CDK13_MOUSE Cyclin-dependent kinase 13 OS=Mus musculus OX=10090 GN=Cdk13 PE=1 SV=3 Length=1511 Score = 92.8 bits (229), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 68/212 (32%), Positives = 103/212 (49%), Gaps = 31/212 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958 +GEG +G+V Y + TGEMVA+K ++ D + G+ +EI ILR L H+ Sbjct 711 IGEGTYGQV----YKARDKDTGEMVALKKVRLD---NEKEGFPITAIREIKILRQLTHQS 763 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL----------FAQQIC 1008 II K D+ E +L + + +Y+ +GL + L F +Q+ Sbjct 764 IINMKEIVTDK-EDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLM 822 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK--AVPEGHEYYRVREDGDSPVF 1066 EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ + E Y Sbjct 823 EGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYT-----NKVITL 877 Query 1067 WYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096 WY P L E ++ A DVWS G L EL T Sbjct 878 WYRPPELLLGEERYTPAIDVWSCGCILGELFT 909 Score = 35.8 bits (81), Expect = 3.5, Method: Compositional matrix adjust. Identities = 57/242 (24%), Positives = 92/242 (38%), Gaps = 54/242 (22%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 VD+ +I + +G+GT VY+ R D + G+M V LK Sbjct 702 VDKFDIIGI--IGEGTYGQVYKAR-------DKDTGEM-----------------VALKK 735 Query 644 --LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI----------MVTEYVE 691 LD + ++ Q++H + + + + + +V EY++ Sbjct 736 VRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMD 795 Query 692 HGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 H D+ E G V + + +QL L Y KN +H ++ NILL G Sbjct 796 H---DLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQ-- 850 Query 750 GTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKWGFGATLL 805 IKL+D G+ S E R ++ W P L G + A+D W G L Sbjct 851 -----IKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILG 905 Query 806 EI 807 E+ Sbjct 906 EL 907 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens OX=9606 GN=STK10 PE=1 SV=1 Length=968 Score = 92.4 bits (228), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 60/200 (30%), Positives = 105/200 (53%), Gaps = 17/200 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +LG+G FGKV Y N TG + A K ++ + + EI+IL T H +I+K Sbjct 41 ELGDGAFGKV----YKAKNKETGALAAAKVIETK-SEEELEDYIVEIEILATCDHPYIVK 95 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019 G G+ L +++E+ P G++ + GL Q+ + +Q+ E + +LH++ Sbjct 96 LLGAYYHDGK--LWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHSKRI 153 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP-----ECLK 1074 IHRDL A NVL+ + +++ DFG++ + + + R+ +W AP E +K Sbjct 154 IHRDLKAGNVLMTLEGDIRLADFGVS---AKNLKTLQKRDSFIGTPYWMAPEVVMCETMK 210 Query 1075 EYKFYYASDVWSFGVTLYEL 1094 + + Y +D+WS G+TL E+ Sbjct 211 DTPYDYKADIWSLGITLIEM 230 Score = 42.0 bits (97), Expect = 0.039, Method: Compositional matrix adjust. Identities = 38/133 (29%), Positives = 62/133 (47%), Gaps = 17/133 (13%) Query 684 IMVTEYVEHGPLD-VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 IM+ E+ G +D + L +RG + VV +Q+ AL++L +K ++H ++ N+L+ Sbjct 108 IMI-EFCPGGAVDAIMLELDRG-LTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLM 165 Query 743 ARLGLAEGTSPFIKLSDPGV---GLGALSREERVERIP-WLAPE---CLPGGANSLSTAM 795 G I+L+D GV L L + + P W+APE C Sbjct 166 TLEG-------DIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKA 218 Query 796 DKWGFGATLLEIC 808 D W G TL+E+ Sbjct 219 DIWSLGITLIEMA 231 >sp|E1BB52|CDK13_BOVIN Cyclin-dependent kinase 13 OS=Bos taurus OX=9913 GN=CDK13 PE=3 SV=1 Length=1512 Score = 92.8 bits (229), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 68/212 (32%), Positives = 103/212 (49%), Gaps = 31/212 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958 +GEG +G+V Y + TGEMVA+K ++ D + G+ +EI ILR L H+ Sbjct 712 IGEGTYGQV----YKARDKDTGEMVALKKVRLD---NEKEGFPITAIREIKILRQLTHQS 764 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL----------FAQQIC 1008 II K D+ E +L + + +Y+ +GL + L F +Q+ Sbjct 765 IINMKEIVTDK-EDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLM 823 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK--AVPEGHEYYRVREDGDSPVF 1066 EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ + E Y Sbjct 824 EGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYT-----NKVITL 878 Query 1067 WYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096 WY P L E ++ A DVWS G L EL T Sbjct 879 WYRPPELLLGEERYTPAIDVWSCGCILGELFT 910 Score = 36.2 bits (82), Expect = 2.7, Method: Compositional matrix adjust. Identities = 57/242 (24%), Positives = 92/242 (38%), Gaps = 54/242 (22%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 VD+ +I + +G+GT VY+ R D + G+M V LK Sbjct 703 VDKFDIIGI--IGEGTYGQVYKAR-------DKDTGEM-----------------VALKK 736 Query 644 --LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI----------MVTEYVE 691 LD + ++ Q++H + + + + + +V EY++ Sbjct 737 VRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMD 796 Query 692 HGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 H D+ E G V + + +QL L Y KN +H ++ NILL G Sbjct 797 H---DLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQ-- 851 Query 750 GTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKWGFGATLL 805 IKL+D G+ S E R ++ W P L G + A+D W G L Sbjct 852 -----IKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILG 906 Query 806 EI 807 E+ Sbjct 907 EL 908 >sp|Q9FN92|Y5597_ARATH Probable receptor-like protein kinase At5g59700 OS=Arabidopsis thaliana OX=3702 GN=At5g59700 PE=1 SV=1 Length=829 Score = 92.4 bits (228), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 76/230 (33%), Positives = 117/230 (51%), Gaps = 27/230 (12%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHE 957 R +G G FGKV +DGT VAVK P+ + G ++ EI++L H Sbjct 486 RAIGVGGFGKV---YKGELHDGT--KVAVKR----ANPKSQQGLAEFRTEIEMLSQFRHR 536 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ-QICEGMA---- 1012 H++ G C++ E + LV EY+ G+L+ +L + GL L + +IC G A Sbjct 537 HLVSLIGYCDENNE--MILVYEYMENGTLKSHL--YGSGLLSLSWKQRLEICIGSARGLH 592 Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH A+ IHRD+ + N+LLD + + K+ DFGL+K PE + + V + Sbjct 593 YLHTGDAKPVIHRDVKSANILLDENLMAKVADFGLSKTGPEIDQTH-VSTAVKGSFGYLD 651 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 PE + + SDV+SFGV ++E+L C PT E++ +A+ M Sbjct 652 PEYFRRQQLTEKSDVYSFGVVMFEVL--CARPVIDPTLTREMVNLAEWAM 699 Score = 47.4 bits (111), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 9/175 (5%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K +P F ++SQ H HL + G C E I+V EY+E+G L Sbjct 506 KVAVKRANPKSQQGLAEFRTEIEMLSQFRHRHLVSLIGYCDENNEMILVYEYMENGTLKS 565 Query 698 WLRRERGHVPMAWKMVVAQQLASA--LSYL---ENKNLVHGNVCGRNILLARLGLAEGTS 752 L G + ++WK + + SA L YL + K ++H +V NILL +A+ Sbjct 566 HLYGS-GLLSLSWKQRLEICIGSARGLHYLHTGDAKPVIHRDVKSANILLDENLMAKVAD 624 Query 753 PFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 + + P + +S + +L PE L+ D + FG + E+ Sbjct 625 FGLSKTGPEIDQTHVSTAVK-GSFGYLDPEYFR--RQQLTEKSDVYSFGVVMFEV 676 >sp|Q14004|CDK13_HUMAN Cyclin-dependent kinase 13 OS=Homo sapiens OX=9606 GN=CDK13 PE=1 SV=2 Length=1512 Score = 92.8 bits (229), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 68/212 (32%), Positives = 103/212 (49%), Gaps = 31/212 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958 +GEG +G+V Y + TGEMVA+K ++ D + G+ +EI ILR L H+ Sbjct 711 IGEGTYGQV----YKARDKDTGEMVALKKVRLD---NEKEGFPITAIREIKILRQLTHQS 763 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL----------FAQQIC 1008 II K D+ E +L + + +Y+ +GL + L F +Q+ Sbjct 764 IINMKEIVTDK-EDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLM 822 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK--AVPEGHEYYRVREDGDSPVF 1066 EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ + E Y Sbjct 823 EGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYT-----NKVITL 877 Query 1067 WYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096 WY P L E ++ A DVWS G L EL T Sbjct 878 WYRPPELLLGEERYTPAIDVWSCGCILGELFT 909 Score = 38.1 bits (87), Expect = 0.73, Method: Compositional matrix adjust. Identities = 65/277 (23%), Positives = 102/277 (37%), Gaps = 68/277 (25%) Query 549 RCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRL 608 + C P+ GET I G R VD+ +I + +G+GT VY+ R Sbjct 681 KICGPRYGETKEKDIDWGKRC--------------VDKFDIIGI--IGEGTYGQVYKAR- 723 Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV--LDPSHHDIALAFYETASLMSQVS 666 D + G+M V LK LD + ++ Q++ Sbjct 724 ------DKDTGEM-----------------VALKKVRLDNEKEGFPITAIREIKILRQLT 760 Query 667 HTHLAFVHGVCVRGPENI----------MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA- 715 H + + + + + +V EY++H D+ E G V + + Sbjct 761 HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDH---DLMGLLESGLVHFNENHIKSF 817 Query 716 -QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-- 772 +QL L Y KN +H ++ NILL G IKL+D G+ S E R Sbjct 818 MRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQ-------IKLADFGLARLYSSEESRPY 870 Query 773 VERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 ++ W P L G + A+D W G L E+ Sbjct 871 TNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGEL 907 >sp|Q6AWJ9|PTK7_DROME Tyrosine-protein kinase-like otk OS=Drosophila melanogaster OX=7227 GN=otk PE=1 SV=1 Length=1033 Score = 92.4 bits (228), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 63/259 (24%), Positives = 123/259 (47%), Gaps = 31/259 (12%) Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 G ++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY Sbjct 778 GLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPH--YMVLEYT 835 Query 982 PLGSLRDYLPRHS---------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 G L+ +L + + +Q+L A QI GM ++ + HRDLA Sbjct 836 DWGDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLAT 895 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RN ++ ++ +VK+ L K EY++ R + P+ W APEC++E ++ SD+++ Sbjct 896 RNCVISSEFIVKVSYPALCKD-KYSREYHKHR-NTLLPIRWLAPECIQEDEYTTKSDIFA 953 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 +GV ++EL +++ P + + + Q L + + P + Sbjct 954 YGVVVWELFNQ--ATKLPHEELTNEQVVQRSQAGSLEWS----------VAEATPDSLRE 1001 Query 1147 LMKNCWETEASFRPTFENL 1165 ++ +CW + RP+F L Sbjct 1002 ILLSCWVSNPKERPSFSQL 1020 Score = 56.6 bits (135), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 66/264 (25%), Positives = 105/264 (40%), Gaps = 44/264 (17%) Query 634 GQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 G E V++K L+ + A F L+ +SH + + G+C + MV EY + Sbjct 778 GLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDW 837 Query 693 GPLDVWLRRERGHVPMAWK-------------MVVAQQLASALSYLENKNLVHGNVCGRN 739 G L +L G V A + VA Q+A + + H ++ RN Sbjct 838 GDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRN 897 Query 740 ILLARLGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLST 793 ++ +S FI K+S P + SRE R I WLAPEC+ + +T Sbjct 898 CVI--------SSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQ--EDEYTT 947 Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQH------RLPEPSCPQLATL 844 D + +G + E+ F+ L P E+ E QR + E + L + Sbjct 948 KSDIFAYGVVVWEL-FNQATKL----PHEELTNEQVVQRSQAGSLEWSVAEATPDSLREI 1002 Query 845 TSQCLTYEPTQRPSFRTILRDLTR 868 C P +RPSF + L++ Sbjct 1003 LLSCWVSNPKERPSFSQLGAALSK 1026 >sp|Q6J9G1|STYK1_MOUSE Tyrosine-protein kinase STYK1 OS=Mus musculus OX=10090 GN=Styk1 PE=2 SV=2 Length=429 Score = 90.5 bits (223), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 73/269 (27%), Positives = 116/269 (43%), Gaps = 34/269 (13%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 V +KAL+ G Q + I + L H+++++ +GCC ++ L +++E V G Sbjct 149 VVLKALEDPVGLQEVQDFIGRIQFYQYLGKHKNLVQLEGCCTER--LPLYMMLEDVVPGD 206 Query 986 LRDYL--PRHSIGLAQLLLF----------AQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033 L +L R + LL+ +QI + +L +H H D+AARN+L+ + Sbjct 207 LLSFLWTCRRDVMTMDGLLYDLTEKQIYHIGKQILLALEFLQEKHLFHGDVAARNILIQS 266 Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 D K+ GLA V H P+ W APE L D+WSFG+ LYE Sbjct 267 DLTPKLCHLGLAYEV-HAHGAISSARSSTIPLKWLAPERLLLRPASIRGDIWSFGILLYE 325 Query 1094 LLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 ++T + PPT L + L+R + + RP C +Y++MK C Sbjct 326 MVTLGAPPYPEVPPTSIL----------------QYLQRKKIMKRPSSCSHAMYNIMKCC 369 Query 1152 WETEASFRPTFENLIPILKTVHEKYQGQA 1180 W RP L+ L+ +A Sbjct 370 WRWSEDSRPLLGQLLQRLEAASRSADDKA 398 Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 50/165 (30%), Positives = 69/165 (42%), Gaps = 25/165 (15%) Query 714 VAQQLASALSYLENKNLVHGNVCGRNIL--------LARLGLAEGTSPFIKLSDPGVGLG 765 + +Q+ AL +L+ K+L HG+V RNIL L LGLA G Sbjct 236 IGKQILLALEFLQEKHLFHGDVAARNILIQSDLTPKLCHLGLAYEVHAH----------G 285 Query 766 ALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 A+S R IP WLAPE L S+ D W FG L E+ G P P+ Sbjct 286 AIS-SARSSTIPLKWLAPERLLLRPASIRG--DIWSFGILLYEMVTLGAPPYPEVPPTSI 342 Query 824 EHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866 + QR+ + P SC + + C + RP +L+ L Sbjct 343 LQYLQRKKIMKRPSSCSHAMYNIMKCCWRWSEDSRPLLGQLLQRL 387 >sp|O65530|PEK14_ARATH Proline-rich receptor-like protein kinase PERK14 OS=Arabidopsis thaliana OX=3702 GN=PERK14 PE=2 SV=1 Length=731 Score = 92.0 bits (227), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 71/201 (35%), Positives = 100/201 (50%), Gaps = 15/201 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG V G VAVK LK R ++ E+D + ++H+H++ Sbjct 395 LGEGGFGYVHKGVLK-----NGTEVAVKQLKIGSYQGERE-FQAEVDTISRVHHKHLVSL 448 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMAYLH---A 1016 G C + G+K L LV E+VP +L +L + + + L A +G+AYLH + Sbjct 449 VGYCVN-GDKRL-LVYEFVPKDTLEFHLHENRGSVLEWEMRLRIAVGAAKGLAYLHEDCS 506 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075 IHRD+ A N+LLD+ K+ DFGLAK + + + F Y APE Sbjct 507 PTIIHRDIKAANILLDSKFEAKVSDFGLAKFFSDTNSSFTHISTRVVGTFGYMAPEYASS 566 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 K SDV+SFGV L EL+T Sbjct 567 GKVTDKSDVYSFGVVLLELIT 587 Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 51/187 (27%), Positives = 79/187 (42%), Gaps = 31/187 (17%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K L + F +S+V H HL + G CV G + ++V E+V L+ Sbjct 414 VAVKQLKIGSYQGEREFQAEVDTISRVHHKHLVSLVGYCVNGDKRLLVYEFVPKDTLEFH 473 Query 699 LRRERGHVPMAWKM--VVAQQLASALSYLE---NKNLVHGNVCGRNILL--------ARL 745 L RG V + W+M +A A L+YL + ++H ++ NILL + Sbjct 474 LHENRGSV-LEWEMRLRIAVGAAKGLAYLHEDCSPTIIHRDIKAANILLDSKFEAKVSDF 532 Query 746 GLA----EGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 GLA + S F +S VG ++APE G ++ D + FG Sbjct 533 GLAKFFSDTNSSFTHISTRVVGT-----------FGYMAPEYASSG--KVTDKSDVYSFG 579 Query 802 ATLLEIC 808 LLE+ Sbjct 580 VVLLELI 586 >sp|B4QC63|PTK7_DROSI Tyrosine-protein kinase-like otk OS=Drosophila simulans OX=7240 GN=otk PE=3 SV=1 Length=1029 Score = 92.4 bits (228), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 63/259 (24%), Positives = 123/259 (47%), Gaps = 31/259 (12%) Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 G ++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY Sbjct 774 GLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPH--YMVLEYT 831 Query 982 PLGSLRDYLPRHS---------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 G L+ +L + + +Q+L A QI GM ++ + HRDLA Sbjct 832 DWGDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLAT 891 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RN ++ ++ +VK+ L K EY++ R + P+ W APEC++E ++ SD+++ Sbjct 892 RNCVISSEFIVKVSYPALCKD-KYSREYHKHR-NTLLPIRWLAPECIQEDEYTTKSDIFA 949 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 +GV ++EL +++ P + + + Q L + + P + Sbjct 950 YGVVVWELFNQ--ATKLPHEELTNEQVVQRSQAGSLEWS----------VAEATPDSLRE 997 Query 1147 LMKNCWETEASFRPTFENL 1165 ++ +CW + RP+F L Sbjct 998 ILLSCWVSNPKERPSFSQL 1016 Score = 56.6 bits (135), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 66/264 (25%), Positives = 105/264 (40%), Gaps = 44/264 (17%) Query 634 GQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 G E V++K L+ + A F L+ +SH + + G+C + MV EY + Sbjct 774 GLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDW 833 Query 693 GPLDVWLRRERGHVPMAWK-------------MVVAQQLASALSYLENKNLVHGNVCGRN 739 G L +L G V A + VA Q+A + + H ++ RN Sbjct 834 GDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRN 893 Query 740 ILLARLGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLST 793 ++ +S FI K+S P + SRE R I WLAPEC+ + +T Sbjct 894 CVI--------SSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQ--EDEYTT 943 Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQH------RLPEPSCPQLATL 844 D + +G + E+ F+ L P E+ E QR + E + L + Sbjct 944 KSDIFAYGVVVWEL-FNQATKL----PHEELTNEQVVQRSQAGSLEWSVAEATPDSLREI 998 Query 845 TSQCLTYEPTQRPSFRTILRDLTR 868 C P +RPSF + L++ Sbjct 999 LLSCWVSNPKERPSFSQLGAALSK 1022 >sp|Q9FID8|Y5900_ARATH Putative receptor-like protein kinase At5g39000 OS=Arabidopsis thaliana OX=3702 GN=At5g39000 PE=3 SV=1 Length=873 Score = 92.4 bits (228), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 66/202 (33%), Positives = 98/202 (49%), Gaps = 16/202 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V Y DG +VAVK L+ Q ++ E+++L L H H++ Sbjct 524 IGVGGFGSV----YKGQIDGGATLVAVKRLEITSN-QGAKEFETELEMLSKLRHVHLVSL 578 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ--QIC----EGMAYLHA 1016 G C++ E + LV EY+P G+L+D+L R L + + +IC G+ YLH Sbjct 579 IGYCDEDNE--MVLVYEYMPHGTLKDHLFRRDKTSDPPLSWKRRLEICIGAARGLQYLHT 636 Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRD+ N+LLD + + K+ DFGL++ P V + PE Sbjct 637 GAKYTIIHRDIKTTNILLDENFVTKVSDFGLSRVGPTSASQTHVSTVVKGTFGYLDPEYY 696 Query 1074 KEYKFYYASDVWSFGVTLYELL 1095 + SDV+SFGV L E+L Sbjct 697 RRQVLTEKSDVYSFGVVLLEVL 718 Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 63/240 (26%), Positives = 102/240 (43%), Gaps = 36/240 (15%) Query 601 TNVYEGRL--RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYET 658 TN +E +L V G G +G++D G V +K L+ + + A F Sbjct 515 TNDFEDKLIIGVGGFGSVYKGQID-----------GGATLVAVKRLEITSNQGAKEFETE 563 Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRER-GHVPMAWK--MVV 714 ++S++ H HL + G C E ++V EY+ HG L D RR++ P++WK + + Sbjct 564 LEMLSKLRHVHLVSLIGYCDEDNEMVLVYEYMPHGTLKDHLFRRDKTSDPPLSWKRRLEI 623 Query 715 AQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG---VGLGALS 768 A L YL ++H ++ NILL + K+SD G VG + S Sbjct 624 CIGAARGLQYLHTGAKYTIIHRDIKTTNILLDE-------NFVTKVSDFGLSRVGPTSAS 676 Query 769 REERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + + +L PE L+ D + FG LLE+ +QS P + + Sbjct 677 QTHVSTVVKGTFGYLDPEYYR--RQVLTEKSDVYSFGVVLLEVLCCRPIRMQSVPPEQAD 734 >sp|Q0KHQ5|TAO_DROME Serine/threonine-protein kinase Tao OS=Drosophila melanogaster OX=7227 GN=Tao PE=1 SV=1 Length=1039 Score = 92.4 bits (228), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 72/211 (34%), Positives = 110/211 (52%), Gaps = 27/211 (13%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---QEIDI 950 ++ + +R++G G FG V Y + T E+VA+K + + G Q + W+ +EI Sbjct 24 EKIFEDLREIGHGSFGAV----YYARCNLTREIVAIKKM-SYTGKQSQEKWQDILKEIRF 78 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC-- 1008 LR L H + I+YKGC E + LVMEY +GS D + H L + + A IC Sbjct 79 LRQLNHPNTIEYKGCY--LRESTAWLVMEYC-VGSASDIIEVHKKPLHEDEIAA--ICLG 133 Query 1009 --EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G++YLH+ IHRD+ A N+LL ++ +VK+ DFG A + + +P + Sbjct 134 VLSGLSYLHSLGRIHRDIKAGNILLTDNGVVKLADFGSAAIKCPANSFV------GTP-Y 186 Query 1067 WYAPE---CLKEYKFYYASDVWSFGVTLYEL 1094 W APE + E ++ DVWS G+T EL Sbjct 187 WMAPEVILAMDEGQYDGKVDVWSLGITCIEL 217 Score = 36.6 bits (83), Expect = 1.8, Method: Compositional matrix adjust. Identities = 46/190 (24%), Positives = 70/190 (37%), Gaps = 20/190 (11%) Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL 779 S LSYL + +H ++ NILL G+ +KL+D G V W+ Sbjct 136 SGLSYLHSLGRIHRDIKAGNILLTDNGV-------VKLADFGSAAIKCPANSFVGTPYWM 188 Query 780 APEC-LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838 APE L +D W G T +E+ + S H Q + P+ Sbjct 189 APEVILAMDEGQYDGKVDVWSLGITCIELAERKPPYFNMNAMSALYHIAQNE----SPTL 244 Query 839 PQ------LATLTSQCLTYEPTQRPSFRTILRD--LTRLQPHNLADVLTVNPDSPASDPT 890 P+ + CL P +RPS +L +TR + + L S + Sbjct 245 PKNDWSDAFCSFVELCLKKMPAERPSSAKLLTHAYVTRPRSDTVLLELIARTKSAVRELD 304 Query 891 VFHKRYLKKI 900 + R +KKI Sbjct 305 NLNYRKMKKI 314 >sp|P48963|CDK2_MESAU Cyclin-dependent kinase 2 OS=Mesocricetus auratus OX=10036 GN=CDK2 PE=2 SV=1 Length=298 Score = 88.2 bits (217), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 61/203 (30%), Positives = 100/203 (49%), Gaps = 11/203 (5%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955 +K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ L Sbjct 4 FQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH 1015 H +I+K + + L + + L D I L + + Q+ +G+A+ H Sbjct 60 HPNIVKLLDVIHTENKLYLVFELLHQDLKKFMDASAVTGIPLPLIKSYLFQLLQGLAFCH 119 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074 + +HRDL +N+L++ + +K+ DFGLA+A Y + WY APE L Sbjct 120 SHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTY----THEVVTLWYRAPEILL 175 Query 1075 EYKFY-YASDVWSFGVTLYELLT 1096 K+Y A D+WS G E++T Sbjct 176 GCKYYSTAVDIWSLGCIFAEMVT 198 Score = 37.0 bits (84), Expect = 0.92, Method: Compositional matrix adjust. Identities = 49/194 (25%), Positives = 83/194 (43%), Gaps = 46/194 (24%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREER 772 QL L++ + ++H ++ +N+L+ AEG+ IKL+D G+ G+ + Sbjct 110 QLLQGLAFCHSHRVLHRDLKPQNLLIN----AEGS---IKLADFGLARAFGVPVRTYTHE 162 Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQS------RSPS 821 V + + APE L G STA+D W G E+ F G++ + + Sbjct 163 VVTLWYRAPEIL-LGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGT 221 Query 822 EKEHFYQRQHRLPE--PSCPQLA----------------TLTSQCLTYEPTQRPSFRTIL 863 E + +P+ PS P+ A +L SQ L Y+P +R S + L Sbjct 222 PDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAAL 281 Query 864 -----RDLTRLQPH 872 +D+T+ PH Sbjct 282 AHPFFQDVTKPVPH 295 >sp|O19004|ARAF_PIG Serine/threonine-protein kinase A-Raf OS=Sus scrofa OX=9823 GN=ARAF PE=2 SV=1 Length=606 Score = 91.7 bits (226), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 74/261 (28%), Positives = 115/261 (44%), Gaps = 42/261 (16%) Query 927 VAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 VAVK LK A + +K E+ +LR H +I+ + G G ++ ++ S Sbjct 333 VAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG---FAIITQWCEGSS 389 Query 986 LRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 L +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L VKIGDFG Sbjct 390 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFG 449 Query 1044 LAKAVPEGHEYYRVREDGDSP-------VFWYAPECLKEYK---FYYASDVWSFGVTLYE 1093 LA + R G P V W A E ++ + + SDV+++GV LYE Sbjct 450 LATV--------KTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYE 501 Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK----CPCEVYHLMK 1149 L+T L I + ++ RG P K CP + L+ Sbjct 502 LMTGS----------LPYSHIGSRDQIIF----MVGRGYLSPDLSKISSNCPKAMRRLLS 547 Query 1150 NCWETEASFRPTFENLIPILK 1170 +C + + RP F ++ ++ Sbjct 548 DCLKFQREERPLFPQILATIE 568 Score = 59.7 bits (143), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 68/255 (27%), Positives = 106/255 (42%), Gaps = 24/255 (9%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 GR G VLKV P+ A AF ++ + H ++ G R P ++T++ Sbjct 327 GRWHGDVAVKVLKVAQPTAEQ-AQAFKNEMQVLRKTRHVNILLFMGFMTR-PGFAIITQW 384 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 E L L M + VA+Q A + YL KN++H ++ NI L E Sbjct 385 CEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIF-----LHE 439 Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802 G + +K+ D G+ GA E+ + W+A E + N S D + +G Sbjct 440 GLT--VKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 497 Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855 L E+ G P ++ F R + P+ S CP+ + L S CL ++ + Sbjct 498 VLYEL-MTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREE 556 Query 856 RPSFRTILRDLTRLQ 870 RP F IL + LQ Sbjct 557 RPLFPQILATIELLQ 571 >sp|Q9C660|PEK10_ARATH Proline-rich receptor-like protein kinase PERK10 OS=Arabidopsis thaliana OX=3702 GN=PERK10 PE=1 SV=2 Length=762 Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 72/212 (34%), Positives = 102/212 (48%), Gaps = 25/212 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG+V +VAVK LK G R +K E+D + ++H +++ Sbjct 436 LGEGGFGRVYKGVLP-----DERVVAVKQLKIGGGQGDRE-FKAEVDTISRVHHRNLLSM 489 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL-----AQLLLFAQQICEGMAYLHAQ 1017 G C + + L+ +YVP +L Y H+ G A + A G+AYLH Sbjct 490 VGYCISENRR--LLIYDYVPNNNL--YFHLHAAGTPGLDWATRVKIAAGAARGLAYLHED 545 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECL 1073 IHRD+ + N+LL+N+ + DFGLAK + + + R G F Y APE Sbjct 546 CHPRIIHRDIKSSNILLENNFHALVSDFGLAKLALDCNTHITTRVMG---TFGYMAPEYA 602 Query 1074 KEYKFYYASDVWSFGVTLYELLTH---CDSSQ 1102 K SDV+SFGV L EL+T D+SQ Sbjct 603 SSGKLTEKSDVFSFGVVLLELITGRKPVDASQ 634 Score = 35.8 bits (81), Expect = 3.0, Method: Compositional matrix adjust. Identities = 44/184 (24%), Positives = 74/184 (40%), Gaps = 21/184 (11%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F +S+V H +L + G C+ +++ +YV + L L G + W ++ Sbjct 471 FKAEVDTISRVHHRNLLSMVGYCISENRRLLIYDYVPNNNLYFHL-HAAGTPGLDWATRV 529 Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 +A A L+YL ++H ++ NILL A +SD G+ AL Sbjct 530 KIAAGAARGLAYLHEDCHPRIIHRDIKSSNILLENNFHA-------LVSDFGLAKLALDC 582 Query 770 EERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++APE G L+ D + FG LLE+ G P+ + P E Sbjct 583 NTHITTRVMGTFGYMAPEYASSG--KLTEKSDVFSFGVVLLEL-ITGRKPVDASQPLGDE 639 Query 825 HFYQ 828 + Sbjct 640 SLVE 643 >sp|Q5ZJK4|STK4_CHICK Serine/threonine-protein kinase 4 OS=Gallus gallus OX=9031 GN=STK4 PE=2 SV=1 Length=486 Score = 90.9 bits (224), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 58/197 (29%), Positives = 96/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V + + TG++VA+K + + Q +EI I++ H+ Sbjct 32 LEKLGEGSYGSV----FKAIHKETGQVVAIKQVPVESDLQE---IIKEISIMQQCDSPHV 84 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 85 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEEEIATIVQSTLKGLEYLHFM 142 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW AP ++E Sbjct 143 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPGVIQEIG 199 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 200 YNCVADIWSLGITAIEM 216 Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust. Identities = 51/214 (24%), Positives = 79/214 (37%), Gaps = 20/214 (9%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q H+ +G + + +V EY G + +R + + Q Sbjct 74 SIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEEEIATIVQSTL 133 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL +H ++ NILL G A KL+D GV +++ V Sbjct 134 KGLEYLHFMRKIHRDIKAGNILLNTEGHA-------KLADFGVAGQLTDTMAKRNTVIGT 186 Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830 P W+AP + G N ++ D W G T +E+ +G+ P P Sbjct 187 PFWMAPGVIQEIGYNCVA---DIWSLGITAIEMA-EGKPPYADIHPMRAIFMIPTNPPPT 242 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R PE QCL P QR + +L+ Sbjct 243 FRKPELWSDAFTDFVKQCLVKSPEQRATAIQLLQ 276 >sp|Q8QFP8|LIMK1_CHICK LIM domain kinase 1 OS=Gallus gallus OX=9031 GN=LIMK1 PE=1 SV=1 Length=662 Score = 91.7 bits (226), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 80/289 (28%), Positives = 129/289 (45%), Gaps = 45/289 (16%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+ T+ TGE++ +K L R+ K E+ ++R L H +++K+ Sbjct 352 LGKGCFGQA----IKVTHRETGEVMVMKELIRFDEETQRTFLK-EVKVMRCLEHPNVLKF 406 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYI 1020 G EK L + EY+ G+LR + +Q + FA+ I GMAYLH+ + I Sbjct 407 IGVL--YKEKRLNFITEYIKGGTLRGLIKSMDSHYPWSQRVSFAKDIAAGMAYLHSMNII 464 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAV---------------PEGHEYYRVREDGDSPV 1065 HRDL + N L+ ++ V + DFGLA+ + P+ + Y V + Sbjct 465 HRDLNSHNCLVRENKSVVVADFGLARLMVDEKNQPEHLQNLKKPDRKKRYTVVGNP---- 520 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELL--THCDSSQSPPTKFLELIGIAQGQMTVLR 1123 +W APE + + D++SFG+ L E++ D P T L Sbjct 521 YWMAPEMINGRSYDEKVDIFSFGIVLCEIIGRVSADPDYLPRTTDFG-----------LN 569 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + LER P CP + + C + + RP+F L L+T+ Sbjct 570 VRGFLERY----CPPACPPSFFPIAACCCDLDPEKRPSFSKLEQWLETL 614 Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 59/256 (23%), Positives = 105/256 (41%), Gaps = 32/256 (13%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +V+K L + F + +M + H ++ GV + +TEY++ G L Sbjct 372 MVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKEKRLNFITEYIKGGTLRGL 431 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL-------------LARL 745 ++ H P + ++ A+ +A+ ++YL + N++H ++ N L LARL Sbjct 432 IKSMDSHYPWSQRVSFAKDIAAGMAYLHSMNIIHRDLNSHNCLVRENKSVVVADFGLARL 491 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAMDKWG 799 + E P L L + +R +R W+APE + G S +D + Sbjct 492 MVDEKNQP--------EHLQNLKKPDRKKRYTVVGNPYWMAPEMING--RSYDEKVDIFS 541 Query 800 FGATLLEIC--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSC-PQLATLTSQCLTYEPTQR 856 FG L EI + R+ + R P+C P + + C +P +R Sbjct 542 FGIVLCEIIGRVSADPDYLPRTTDFGLNVRGFLERYCPPACPPSFFPIAACCCDLDPEKR 601 Query 857 PSFRTILRDLTRLQPH 872 PSF + + L L+ H Sbjct 602 PSFSKLEQWLETLRMH 617 >sp|P52304|POLO_DROME Serine/threonine-protein kinase polo OS=Drosophila melanogaster OX=7227 GN=polo PE=1 SV=2 Length=576 Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 68/217 (31%), Positives = 108/217 (50%), Gaps = 12/217 (6%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 D P + ++ K++R G+G F K CY+ + T ++ A K + +H Sbjct 11 DIPDRLVDINQRKTYKRMRFFGKGGFAK----CYEIIDVETDDVFAGKIVSKKLMIKHNQ 66 Query 943 GWK--QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQ 999 K QEI I R+L H +I+K+ ED +++ +V+E S+ + + R SI + Sbjct 67 KEKTAQEITIHRSLNHPNIVKFHNYFEDS--QNIYIVLELCKKRSMMELHKRRKSITEFE 124 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 + QI +G+ YLH IHRDL N+ L++ VKIGDFGLA + +E R + Sbjct 125 CRYYIYQIIQGVKYLHDNRIIHRDLKLGNLFLNDLLHVKIGDFGLATRIE--YEGERKKT 182 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 +P + APE L + + D+WS G +Y LL Sbjct 183 LCGTPN-YIAPEILTKKGHSFEVDIWSIGCVMYTLLV 218 >sp|Q8BTW9|PAK4_MOUSE Serine/threonine-protein kinase PAK 4 OS=Mus musculus OX=10090 GN=Pak4 PE=1 SV=1 Length=593 Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 71/237 (30%), Positives = 111/237 (47%), Gaps = 21/237 (9%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 L V+P P S YL +GEG G V + T +G++VAVK K D Sbjct 312 LVVDPGDPRS--------YLDNFIKIGEGSTGIVCIA----TVRSSGKLVAVK--KMDLR 357 Query 938 PQHRSGWK-QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996 Q R E+ I+R HE++++ E L +VME++ G+L D + + Sbjct 358 KQQRRELLFNEVVIMRDYRHENVVEMYNSYLVGDE--LWVVMEFLEGGALTDIVTHTRMN 415 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 Q+ + + +A LHAQ IHRD+ + ++LL +D VK+ DFG V E R Sbjct 416 EEQIAAVCLAVLQALAVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQV--SKEVPR 473 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELI 1112 + +P +W APE + + D+WS GV + E++ PP K +++I Sbjct 474 RKSLVGTP-YWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMI 529 >sp|P51956|NEK3_HUMAN Serine/threonine-protein kinase Nek3 OS=Homo sapiens OX=9606 GN=NEK3 PE=1 SV=2 Length=506 Score = 90.9 bits (224), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 70/270 (26%), Positives = 127/270 (47%), Gaps = 27/270 (10%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +R +GEG FG+ L ++ +N +M A+K ++ + ++E +L + H +I Sbjct 7 LRMIGEGSFGRALLVQHESSN----QMFAMKEIRLPKSFSNTQNSRKEAVLLAKMKHPNI 62 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLHA 1016 + +K E +G L +VMEY G L + + L +L + Q+C G+ ++H Sbjct 63 VAFKESFEAEGH--LYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHK 120 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + +HRD+ ++N+ L + VK+GDFG A+ + + +P ++ PE + Sbjct 121 KRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACTY--VGTP-YYVPPEIWENL 177 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 + SD+WS G LYEL T Q+ K L ++ + QG ++ P Sbjct 178 PYNNKSDIWSLGCILYELCTLKHPFQANSWKNL-ILKVCQGCIS--------------PL 222 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 P E+ L+K ++ S RP+ L+ Sbjct 223 PSHYSYELQFLVKQMFKRNPSHRPSATTLL 252 >sp|Q63699|CDK2_RAT Cyclin-dependent kinase 2 OS=Rattus norvegicus OX=10116 GN=Cdk2 PE=1 SV=1 Length=298 Score = 88.2 bits (217), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 64/205 (31%), Positives = 102/205 (50%), Gaps = 15/205 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955 +K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ L Sbjct 4 FQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYV--PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013 H +I+K E L LV E++ L D + L + + Q+ +G+A+ Sbjct 60 HPNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGLPLPLIKSYLFQLLQGLAF 117 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072 H+ +HRDL +N+L++ + +K+ DFGLA+A Y + WY APE Sbjct 118 CHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTY----THEVVTLWYRAPEI 173 Query 1073 LKEYKFY-YASDVWSFGVTLYELLT 1096 L K+Y A D+WS G E++T Sbjct 174 LLGCKYYSTAVDIWSLGCIFAEMVT 198 Score = 37.0 bits (84), Expect = 0.99, Method: Compositional matrix adjust. Identities = 49/194 (25%), Positives = 83/194 (43%), Gaps = 46/194 (24%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREER 772 QL L++ + ++H ++ +N+L+ AEG+ IKL+D G+ G+ + Sbjct 110 QLLQGLAFCHSHRVLHRDLKPQNLLIN----AEGS---IKLADFGLARAFGVPVRTYTHE 162 Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQS------RSPS 821 V + + APE L G STA+D W G E+ F G++ + + Sbjct 163 VVTLWYRAPEIL-LGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGT 221 Query 822 EKEHFYQRQHRLPE--PSCPQLA----------------TLTSQCLTYEPTQRPSFRTIL 863 E + +P+ PS P+ A +L SQ L Y+P +R S + L Sbjct 222 PDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAAL 281 Query 864 -----RDLTRLQPH 872 +D+T+ PH Sbjct 282 AHPFFQDVTKPVPH 295 >sp|B4P5Q9|PTK7_DROYA Tyrosine-protein kinase-like otk OS=Drosophila yakuba OX=7245 GN=otk PE=3 SV=1 Length=1033 Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 63/259 (24%), Positives = 122/259 (47%), Gaps = 31/259 (12%) Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 G ++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY Sbjct 778 GLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPH--YMVLEYT 835 Query 982 PLGSLRDYLPRHS---------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 G L+ +L + + +Q+L A QI GM ++ + HRDLA Sbjct 836 DWGDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLAT 895 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RN ++ ++ +VK+ L K EY++ R + P+ W APEC++E ++ SD+++ Sbjct 896 RNCVISSEFIVKVSYPALCKD-KYSREYHKHR-NTLLPIRWLAPECIQEDEYTTKSDIFA 953 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 +GV ++EL +++ P + + + Q L + + P + Sbjct 954 YGVVVWELFNQ--ATKLPHEELTNEQVVQRSQAGSLEWS----------VAESTPDSLRE 1001 Query 1147 LMKNCWETEASFRPTFENL 1165 ++ +CW RP+F L Sbjct 1002 ILLSCWVANPKERPSFSQL 1020 Score = 56.6 bits (135), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 66/264 (25%), Positives = 105/264 (40%), Gaps = 44/264 (17%) Query 634 GQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 G E V++K L+ + A F L+ +SH + + G+C + MV EY + Sbjct 778 GLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDW 837 Query 693 GPLDVWLRRERGHVPMAWK-------------MVVAQQLASALSYLENKNLVHGNVCGRN 739 G L +L G V A + VA Q+A + + H ++ RN Sbjct 838 GDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRN 897 Query 740 ILLARLGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLST 793 ++ +S FI K+S P + SRE R I WLAPEC+ + +T Sbjct 898 CVI--------SSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQ--EDEYTT 947 Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQH------RLPEPSCPQLATL 844 D + +G + E+ F+ L P E+ E QR + E + L + Sbjct 948 KSDIFAYGVVVWEL-FNQATKL----PHEELTNEQVVQRSQAGSLEWSVAESTPDSLREI 1002 Query 845 TSQCLTYEPTQRPSFRTILRDLTR 868 C P +RPSF + L++ Sbjct 1003 LLSCWVANPKERPSFSQLGAALSK 1026 >sp|Q54RV3|PAKG_DICDI Serine/threonine-protein kinase pakG OS=Dictyostelium discoideum OX=44689 GN=pakG PE=3 SV=1 Length=1179 Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 60/197 (30%), Positives = 103/197 (52%), Gaps = 20/197 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G +G V Y + T ++A+K++ + ++EI IL+ ++I+ Y Sbjct 145 LGTGSYGTV----YKAIHKDTNFVLAIKSIPI----KESEEIEKEISILKKCKSQNIVSY 196 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G + QG+ +L ++MEY S+RD L S+ Q+ + QQ +G+ YLH + I Sbjct 197 FGSGQ-QGD-NLWILMEYCSANSIRDMLELTEKSLTEKQISVILQQALKGLHYLHQSNII 254 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---FWYAPECLKEYK 1077 HRD+ A N+L++ D +VK+ DFG++ + + +R + V W APE +K Sbjct 255 HRDIKAANILINEDAIVKLADFGVSSQLEDS-----LRGEASQLVGTPLWMAPEIIKRQN 309 Query 1078 FYYASDVWSFGVTLYEL 1094 + D+WS G+T E+ Sbjct 310 YNNKCDIWSLGITAIEM 326 Score = 38.1 bits (87), Expect = 0.74, Method: Compositional matrix adjust. Identities = 40/158 (25%), Positives = 65/158 (41%), Gaps = 25/158 (16%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSRE 770 V+ QQ L YL N++H ++ NIL+ + +KL+D GV L R Sbjct 236 VILQQALKGLHYLHQSNIIHRDIKAANILINEDAI-------VKLADFGVSSQLEDSLRG 288 Query 771 ERVERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 E + + W+APE + + + D W G T +E+ + PL + P+ Sbjct 289 EASQLVGTPLWMAPEII--KRQNYNNKCDIWSLGITAIEMA-ESFPPLYTMPPTRAMLMI 345 Query 828 QRQHRLPEPS-------CPQLATLTSQCLTYEPTQRPS 858 + P P+ +L QC +P +RPS Sbjct 346 PNK---PPPTLSKPHHFSKELNDFIGQCCQKDPEKRPS 380 >sp|Q86YV6|MYLK4_HUMAN Myosin light chain kinase family member 4 OS=Homo sapiens OX=9606 GN=MYLK4 PE=1 SV=2 Length=388 Score = 89.4 bits (220), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 69/208 (33%), Positives = 105/208 (50%), Gaps = 23/208 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 + K LG G FG+V + TG +A K +K G + + K EI ++ L H Sbjct 106 VSKTEILGGGRFGQV----HKCEETATGLKLAAKIIKTR-GMKDKEEVKNEISVMNQLDH 160 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYL 1014 ++I+ E + + + LVMEYV G L D + S L +L +LF +QICEG+ ++ Sbjct 161 ANLIQLYDAFESKND--IVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHM 218 Query 1015 HAQHYIHRDLAARNVLLDN--DRLVKIGDFGLAKAVPEGHEYYRVRE----DGDSPVFWY 1068 H + +H DL N+L N + +KI DFGLA+ Y+ RE + +P F Sbjct 219 HQMYILHLDLKPENILCVNRDAKQIKIIDFGLARR-------YKPREKLKVNFGTPEF-L 270 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLT 1096 APE + + +D+WS GV Y LL+ Sbjct 271 APEVVNYDFVSFPTDMWSVGVIAYMLLS 298 >sp|Q2RA93|WNK6_ORYSJ Probable serine/threonine-protein kinase WNK6 OS=Oryza sativa subsp. japonica OX=39947 GN=WNK6 PE=2 SV=1 Length=439 Score = 90.1 bits (222), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 72/248 (29%), Positives = 118/248 (48%), Gaps = 23/248 (9%) Query 876 DVLTVNPDSPASDPTVFHK----RYLKKIRDLGEGHFGKVSLYCYDPTNDGT----GEMV 927 DV P+ P DP V RYL+ +G G K +D DG G++ Sbjct 10 DVADEQPEPPDEDPDVAEADPTGRYLRYREIIGSGS-SKTVYKAFDAV-DGIEVAWGKVE 67 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 + + R + EI +L++L H+HI+K D +++ +V E G+LR Sbjct 68 INERIMGSSKELQR--LRTEIQLLKSLQHKHILKLYASWVDTNRRTVNIVTELFTSGNLR 125 Query 988 DYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFG 1043 +Y +H + + + +A+QI G+ YLH+Q IHRDL N+ ++ N VKIGDFG Sbjct 126 EYRTKHKKVDMKAMRRWAKQILTGLEYLHSQKPPIIHRDLKCDNIFINGNHGKVKIGDFG 185 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 LA + + R + + APE E + D++SFG+ + E++T C+ S Sbjct 186 LAMVMQQ-----RKTRSIQGTIEFMAPELFGE-NYNELVDIYSFGMCMLEMVT-CECPYS 238 Query 1104 PPTKFLEL 1111 F+++ Sbjct 239 ECKGFIQI 246 >sp|Q8IVT5|KSR1_HUMAN Kinase suppressor of Ras 1 OS=Homo sapiens OX=9606 GN=KSR1 PE=1 SV=3 Length=923 Score = 92.0 bits (227), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 77/287 (27%), Positives = 137/287 (48%), Gaps = 42/287 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ-HRSGWKQEIDILRTLYHEHIIK 961 +G+G +G+V + GE VA++ L+ D Q H +K+E+ R HE+++ Sbjct 619 IGQGRWGRVHRGRWH------GE-VAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVL 671 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G C + L ++ + +L ++ P+ S+ + + AQ+I +GM YLHA+ Sbjct 672 FMGACMNPPH--LAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGI 729 Query 1020 IHRDLAARNVLLDNDRLV--KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +H+DL ++NV DN ++V G FG++ V EG +++ D + + APE ++E Sbjct 730 VHKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDW-LCYLAPEIVREMT 788 Query 1078 ---------FYYASDVWSFGVTLYELLTHCD---SSQSPPTKFLELIGIAQGQMTVLRLT 1125 F A+DV++FG YEL D +Q+ + IG +G VL Sbjct 789 PGKDEDQLPFSKAADVYAFGTVWYELQAR-DWPLKNQAAEASIWQ-IGSGEGMKRVLTSV 846 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 L + EV ++ CW + RP+F L+ +L+ + Sbjct 847 SLGK-------------EVSEILSACWAFDLQERPSFSLLMDMLEKL 880 Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust. Identities = 54/261 (21%), Positives = 110/261 (42%), Gaps = 34/261 (13%) Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 E+ + L +D + D F + Q H ++ G C+ P ++T + + L Sbjct 635 EVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTL 694 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 ++R + + + +AQ++ + YL K +VH ++ +N+ + + Sbjct 695 HSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFY--------DNGKV 746 Query 756 KLSDPGV-GLGALSREERVER--------IPWLAPECL----PGGANS---LSTAMDKWG 799 ++D G+ G+ + RE R E + +LAPE + PG S A D + Sbjct 747 VITDFGLFGISGVVREGRRENQLKLSHDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYA 806 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQ------RQHRLPEPSC-PQLATLTSQCLTYE 852 FG E+ + PL+++ + + +Q + L S +++ + S C ++ Sbjct 807 FGTVWYELQAR-DWPLKNQ--AAEASIWQIGSGEGMKRVLTSVSLGKEVSEILSACWAFD 863 Query 853 PTQRPSFRTILRDLTRLQPHN 873 +RPSF ++ L +L N Sbjct 864 LQERPSFSLLMDMLEKLPKLN 884 >sp|Q6FKD4|PHO85_CANGA Negative regulator of the PHO system OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=PHO85 PE=3 SV=1 Length=302 Score = 87.8 bits (216), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 63/209 (30%), Positives = 100/209 (48%), Gaps = 20/209 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 K++ LG G + V Y N TG VA+K +K D S +EI +++ L H Sbjct 6 FKQLEKLGNGTYATV----YKGLNKSTGVYVALKEVKLDSEEGTPSTAIREISLMKELKH 61 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFAQQICE 1009 ++I++ E L LV EY+ L+ Y+ ++G + + F Q+ E Sbjct 62 DNIVRLYDVI--HTENKLTLVFEYMD-NDLKKYMDSRTVGNAPRGLEMNLVKYFQWQLLE 118 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068 G+A+ H +HRDL +N+L+ +K+GDFGLA+A + + WY Sbjct 119 GLAFCHENKILHRDLKPQNLLITKRGQLKLGDFGLARAFGIPVNTF----SSEVVTLWYR 174 Query 1069 APECLKEYKFYYAS-DVWSFGVTLYELLT 1096 AP+ L + Y S D+WS G L E++T Sbjct 175 APDVLMGSRTYSTSIDIWSCGCILAEMIT 203 Score = 46.2 bits (108), Expect = 0.001, Method: Compositional matrix adjust. Identities = 71/319 (22%), Positives = 128/319 (40%), Gaps = 64/319 (20%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--VLD 645 + QL LG GT VY+G + G + V LK LD Sbjct 5 QFKQLEKLGNGTYATVYKGLNKSTG------------------------VYVALKEVKLD 40 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + A E SLM ++ H ++ ++ V + +V EY+++ R G+ Sbjct 41 SEEGTPSTAIREI-SLMKELKHDNIVRLYDVIHTENKLTLVFEYMDNDLKKYMDSRTVGN 99 Query 706 VPMAWKMVVAQ----QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 P +M + + QL L++ ++H ++ +N+L+ + G +KL D G Sbjct 100 APRGLEMNLVKYFQWQLLEGLAFCHENKILHRDLKPQNLLITKRGQ-------LKLGDFG 152 Query 762 V----GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + G+ + V + + AP+ L G+ + ST++D W G L E+ + Sbjct 153 LARAFGIPVNTFSSEVVTLWYRAPDVL-MGSRTYSTSIDIWSCGCILAEMITGKPLFPGT 211 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL-RDL-TRLQPH--- 872 + + + + E + P + +L P P+F+ L +DL LQP+ Sbjct 212 NDEEQLKLIFDKMGTPNETTWPGVTSL--------PKYNPNFQQRLPKDLKAELQPYVKE 263 Query 873 ----NLAD----VLTVNPD 883 N+ D +L +NPD Sbjct 264 PLDDNVIDLLHGLLQLNPD 282 >sp|Q61G93|ROL3_CAEBR Protein roller-3 OS=Caenorhabditis briggsae OX=6238 GN=rol-3 PE=3 SV=3 Length=2439 Score = 92.4 bits (228), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 74/265 (28%), Positives = 123/265 (46%), Gaps = 30/265 (11%) Query 927 VAVKALKADCGPQH--RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 VAVK L+ R + +E +L L H +I+K G C G+ +++EY+ G Sbjct 1960 VAVKQLRPKSANHDFDRMMFMKEAILLNNLDH-NIVKELGVCVSPGQG--LILLEYMEGG 2016 Query 985 SLRDYLPRHS--------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036 +L ++L + + LL + I GM YL ++H++L+AR LL Sbjct 2017 NLLNFLRESAPSEMQASELSTRDLLAISVDIARGMNYLERLPHVHKNLSARKCLLSGRPG 2076 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 V + G+ +A+ +G E RV + V W APE K+ F SDVW++GV LYE+ + Sbjct 2077 VAKLEMGMPRALSKG-EINRVDLESMQSVKWMAPEVFKDLMFTSKSDVWAYGVLLYEIFS 2135 Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLR-LTELLERGERLPRPDKCPC-EVYHLMKNCWET 1154 + G M R +T++ + LP P CP ++ +MK C + Sbjct 2136 FGEE--------------PYGSMDSRRVITDVRDGNLTLPVPPYCPSKKICKVMKMCLIS 2181 Query 1155 EASFRPTFENLIPILKTVHEKYQGQ 1179 + + R +F ++ I +T + Q Q Sbjct 2182 DPNKRASFATILKIFETCRDDQQSQ 2206 Score = 70.9 bits (172), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 68/248 (27%), Positives = 119/248 (48%), Gaps = 27/248 (11%) Query 635 QELRVVLKVLDP--SHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 ++++V +K L P ++HD + F + A L++ + H ++ GVCV + +++ EY+E Sbjct 1956 KQVKVAVKQLRPKSANHDFDRMMFMKEAILLNNLDH-NIVKELGVCVSPGQGLILLEYME 2014 Query 692 HGPLDVWLRRERGHVPMAWK------MVVAQQLASALSYLENKNLVHGNVCGRNILLA-R 744 G L +LR A + + ++ +A ++YLE VH N+ R LL+ R Sbjct 2015 GGNLLNFLRESAPSEMQASELSTRDLLAISVDIARGMNYLERLPHVHKNLSARKCLLSGR 2074 Query 745 LGLAEGTSPFIKLSDP-GVGLGALSRE--ERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 G+A+ +++ P + G ++R E ++ + W+APE ++ D W +G Sbjct 2075 PGVAK-----LEMGMPRALSKGEINRVDLESMQSVKWMAPEVFKDLM--FTSKSDVWAYG 2127 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP---EPSCP--QLATLTSQCLTYEPTQR 856 L EI GE P S S + R L P CP ++ + CL +P +R Sbjct 2128 VLLYEIFSFGEEPYGSMD-SRRVITDVRDGNLTLPVPPYCPSKKICKVMKMCLISDPNKR 2186 Query 857 PSFRTILR 864 SF TIL+ Sbjct 2187 ASFATILK 2194 >sp|Q9VXE5|PAKM_DROME Serine/threonine-protein kinase PAK mbt OS=Drosophila melanogaster OX=7227 GN=mbt PE=1 SV=2 Length=639 Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 64/211 (30%), Positives = 101/211 (48%), Gaps = 16/211 (8%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 A DP + L +GEG G V + T+ TG VAVK K D Q R Sbjct 361 AGDP----RENLDHFNKIGEGSTGTVCIA----TDKSTGRQVAVK--KMDLRKQQRRELL 410 Query 946 -QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA 1004 E+ I+R +H +I++ E L +VMEY+ G+L D + + Q+ Sbjct 411 FNEVVIMRDYHHPNIVETYSSFLVNDE--LWVVMEYLEGGALTDIVTHSRMDEEQIATVC 468 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 +Q + +AYLH+Q IHRD+ + ++LL D VK+ DFG V E + + +P Sbjct 469 KQCLKALAYLHSQGVIHRDIKSDSILLAADGRVKLSDFGFCAQV--SQELPKRKSLVGTP 526 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 +W +PE + + D+WS G+ + E++ Sbjct 527 -YWMSPEVISRLPYGPEVDIWSLGIMVIEMV 556 Score = 46.6 bits (109), Expect = 0.002, Method: Compositional matrix adjust. Identities = 59/246 (24%), Positives = 102/246 (41%), Gaps = 32/246 (13%) Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 D+ +V +K +D + +M H ++ + + E +V EY+E Sbjct 387 DKSTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYHHPNIVETYSSFLVNDELWVVMEYLE 446 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G L + R + V +Q AL+YL ++ ++H ++ +ILLA A+G Sbjct 447 GGALTDIVTHSR--MDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLA----ADGR 500 Query 752 SPFIKLSDPG----VGLGALSREERVERIPWLAPEC---LPGGANSLSTAMDKWGFGATL 804 +KLSD G V R+ V W++PE LP G +D W G + Sbjct 501 ---VKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVISRLPYGPE-----VDIWSLGIMV 552 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------CPQLATLTSQCLTYEPTQRP 857 +E+ DGE P + P + +R + P+ P+L + + L +P QR Sbjct 553 IEMV-DGEPPFFNEPPLQA---MRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRA 608 Query 858 SFRTIL 863 + +L Sbjct 609 TAAELL 614 >sp|Q1ZXD6|ROCO5_DICDI Probable serine/threonine-protein kinase roco5 OS=Dictyostelium discoideum OX=44689 GN=roco5 PE=3 SV=1 Length=2800 Score = 92.4 bits (228), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 78/282 (28%), Positives = 128/282 (45%), Gaps = 39/282 (14%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-----WKQEIDIL 951 L+ I +GEG FG V G++VA+K + D G + +++E+ + Sbjct 2175 LEIIEKVGEGGFGIVY------KGKLRGQLVAIKQITIDSGQAEAASEIYREFRREVWLS 2228 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICE 1009 TL H I+ KG C D +VMEY+P G+L +L + SI L A I + Sbjct 2229 NTLTHPSIVSLKGYCLD----PCCIVMEYIPNGTLYSHLRKSFSSITWQLKLKIAINIAD 2284 Query 1010 GMAYLH--AQHYIHRDLAARNVLLDNDR----LVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 + ++H HRDL + N+L+ +D + K+ DFG +AV + D S Sbjct 2285 AIKHMHGFTPKICHRDLKSPNILMLSDMNAAVVCKVSDFGETRAVVTS----ALGRDKLS 2340 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 W +PE ++ ++ +DV+SFG+ L+E+LT P +A + + Sbjct 2341 NPIWLSPEIMRGDEYTEKADVYSFGIVLWEILTGLLPFDEYP--------VAHSSF-MYQ 2391 Query 1124 LTELLERGERLPRPDKCPC---EVYHLMKNCWETEASFRPTF 1162 L + + G R P C + L+ +CW+ + RPTF Sbjct 2392 LEDEITNGLRPTIPQNSVCGHPDFITLITDCWQNDPLKRPTF 2433 Score = 58.9 bits (141), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 67/274 (24%), Positives = 114/274 (42%), Gaps = 32/274 (12%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETAS----LMSQVSHTHLAFVHGVCVRGPENIM 685 G+ RGQ + + +D + A Y L + ++H + + G C+ + Sbjct 2192 GKLRGQLVAIKQITIDSGQAEAASEIYREFRREVWLSNTLTHPSIVSLKGYCLD--PCCI 2249 Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLA 743 V EY+ +G L LR+ + K+ +A +A A+ ++ + H ++ NIL+ Sbjct 2250 VMEYIPNGTLYSHLRKSFSSITWQLKLKIAINIADAIKHMHGFTPKICHRDLKSPNILM- 2308 Query 744 RLGLAEGTSPFI-KLSDPG----VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKW 798 L++ + + K+SD G V AL R++ I WL+PE + G + + D + Sbjct 2309 ---LSDMNAAVVCKVSDFGETRAVVTSALGRDKLSNPI-WLSPEIMRG--DEYTEKADVY 2362 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE---PSCPQ--------LATLTSQ 847 FG L EI G P + YQ + + P+ PQ TL + Sbjct 2363 SFGIVLWEI-LTGLLPFDEYPVAHSSFMYQLEDEITNGLRPTIPQNSVCGHPDFITLITD 2421 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 C +P +RP+F I L + N A T N Sbjct 2422 CWQNDPLKRPTFIDIHSRLLIMSGLNPATATTTN 2455 >sp|Q9N2L7|PLK2_CAEEL Serine/threonine-protein kinase plk-2 OS=Caenorhabditis elegans OX=6239 GN=plk-2 PE=1 SV=1 Length=632 Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 71/217 (33%), Positives = 106/217 (49%), Gaps = 13/217 (6%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQH 940 PD P K +K + LG+G F +CY+ N TGE+ A K + KA Q+ Sbjct 21 PDVPDVILDGERKTRYEKGKFLGKGGFA----HCYELRNKSTGELFAGKVVPKALLIKQY 76 Query 941 -RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLA 998 R QE+ I R L H +++K ED+ ++ + +E P SL + + R ++ Sbjct 77 QRDKMAQEVQIHRNLQHRNVVKLYHFFEDKS--NVYITLELCPRRSLMELHKRRKAVTEP 134 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 + F QI EG+ YLH +HRDL N+ L+++ VKIGDFGLA R + Sbjct 135 EARYFTYQIVEGVLYLHNLKIVHRDLKLGNLFLNDELQVKIGDFGLATTCDNDE---RKK 191 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 +P + APE L + + D+W+ G LY LL Sbjct 192 TLCGTPN-YIAPEVLNKIGHSFEVDLWAIGCILYILL 227 >sp|Q41328|PTI1_SOLLC Pto-interacting protein 1 OS=Solanum lycopersicum OX=4081 GN=PTI1 PE=1 SV=2 Length=354 Score = 88.6 bits (218), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 82/296 (28%), Positives = 131/296 (44%), Gaps = 33/296 (11%) Query 897 LKKIRD-------LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 LK I D +GEG +G+V +G A+K L D Q + ++ Sbjct 61 LKDITDNFGSKALIGEGSYGRVYHGVLK-----SGRAAAIKKL--DSSKQPDREFLAQVS 113 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQ 999 ++ L E++++ G C D G + L EY P GSL D L P + AQ Sbjct 114 MVSRLKDENVVELLGYCVDGGFRVL--AYEYAPNGSLHDILHGRKGVKGAQPGPVLSWAQ 171 Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYY 1055 + A +G+ YLH + H IHRD+ + N+LL +D + KI DF L+ P+ + Sbjct 172 RVKIAVGAAKGLEYLHEKAQPHIIHRDIKSSNILLFDDDVAKIADFDLSNQAPDMAARLH 231 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGI 1114 R G ++APE + SDV+SFGV L ELLT + P L+ Sbjct 232 STRVLG--TFGYHAPEYAMTGQLSSKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTW 289 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 A +++ ++ + ++ P K ++ + C + EA FRP ++ L+ Sbjct 290 ATPRLSEDKVKQCVDARLNTDYPPKAIAKMAAVAALCVQYEADFRPNMSIVVKALQ 345 Score = 46.2 bits (108), Expect = 0.001, Method: Compositional matrix adjust. Identities = 62/247 (25%), Positives = 102/247 (41%), Gaps = 35/247 (14%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRE--RGHVP---M 708 F S++S++ ++ + G CV G ++ EY +G L D+ R+ +G P + Sbjct 108 FLAQVSMVSRLKDENVVELLGYCVDGGFRVLAYEYAPNGSLHDILHGRKGVKGAQPGPVL 167 Query 709 AW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 +W ++ +A A L YL K +++H ++ NILL +A+ LS+ Sbjct 168 SWAQRVKIAVGAAKGLEYLHEKAQPHIIHRDIKSSNILLFDDDVAKIAD--FDLSNQAPD 225 Query 764 LGALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + A RV + APE G LS+ D + FG LLE+ G P+ P Sbjct 226 MAARLHSTRVLGTFGYHAPEYAMTG--QLSSKSDVYSFGVVLLEL-LTGRKPVDHTLPRG 282 Query 823 KEHFYQ-RQHRLPEPSCPQL--ATLTSQ---------------CLTYEPTQRPSFRTILR 864 ++ RL E Q A L + C+ YE RP+ +++ Sbjct 283 QQSLVTWATPRLSEDKVKQCVDARLNTDYPPKAIAKMAAVAALCVQYEADFRPNMSIVVK 342 Query 865 DLTRLQP 871 L L P Sbjct 343 ALQPLLP 349 >sp|Q86IX1|DST1_DICDI Serine/threonine-protein kinase dst1 OS=Dictyostelium discoideum OX=44689 GN=dst1 PE=3 SV=1 Length=737 Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 64/214 (30%), Positives = 108/214 (50%), Gaps = 19/214 (9%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 PD P T++H + LG+G FG+V + + G++VA+K + D + Sbjct 22 PDDPQ---TIYHIQ-----ERLGKGSFGQV----FKAVHFANGKVVAIKIISLD-DQEAI 68 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQL 1000 ++EI IL + +I++Y G + L +VMEY GS+ D L +I ++ Sbjct 69 KDVRKEISILAECNYPNIVQYFGSY--FKDHQLWIVMEYCGGGSVSDLLQVIDTISEDEI 126 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 L ++ +G+ YLH IHRD+ N+LL++ VK+ DFG++ + + R Sbjct 127 ALICREALKGLNYLHEFKKIHRDIKGGNILLNDRGEVKLADFGVSAQL---FNTFSKRNT 183 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 +W APE ++E K+ +DVWS G+T E+ Sbjct 184 FVGTPYWMAPEVIQENKYDGKADVWSLGITAIEM 217 Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust. Identities = 40/166 (24%), Positives = 65/166 (39%), Gaps = 30/166 (18%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSR 769 ++ ++ L+YL +H ++ G NILL G +KL+D GV S+ Sbjct 128 LICREALKGLNYLHEFKKIHRDIKGGNILLNDRGE-------VKLADFGVSAQLFNTFSK 180 Query 770 EERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 P W+APE + N D W G T +E+ + P+ H + Sbjct 181 RNTFVGTPYWMAPEVI--QENKYDGKADVWSLGITAIEMA-------EGLPPNSNVHPMR 231 Query 829 RQHRLPEPSCPQLAT----------LTSQCLTYEPTQRPSFRTILR 864 +P P L S+CLT +P +RP+ + +L Sbjct 232 VIFMIPREESPALTDKSIWSDKFQDFISKCLTKDPAERPTAKELLN 277 >sp|Q9LS95|PERK6_ARATH Putative proline-rich receptor-like protein kinase PERK6 OS=Arabidopsis thaliana OX=3702 GN=PERK6 PE=2 SV=2 Length=700 Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 75/227 (33%), Positives = 106/227 (47%), Gaps = 18/227 (8%) Query 877 VLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC 936 L N + D + + R LG+G FG V G+ +AVK+LKA Sbjct 317 ALGFNKSTFTYDELAAATQGFSQSRLLGQGGFGYVHKGILP-----NGKEIAVKSLKAGS 371 Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-- 994 G R ++ E+DI+ ++H ++ G C G++ LV E++P +L +L S Sbjct 372 GQGERE-FQAEVDIISRVHHRFLVSLVGYCIAGGQR--MLVYEFLPNDTLEFHLHGKSGK 428 Query 995 -IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 + L A +G+AYLH IHRD+ A N+LLD K+ DFGLAK + Sbjct 429 VLDWPTRLKIALGSAKGLAYLHEDCHPRIIHRDIKASNILLDESFEAKVADFGLAKLSQD 488 Query 1051 GHEYYRVREDGDSPVFWY-APECLKEYKFYYASDVWSFGVTLYELLT 1096 + R G F Y APE K SDV+SFGV L EL+T Sbjct 489 NVTHVSTRIMG---TFGYLAPEYASSGKLTDRSDVFSFGVMLLELVT 532 Score = 45.8 bits (107), Expect = 0.003, Method: Compositional matrix adjust. Identities = 46/166 (28%), Positives = 76/166 (46%), Gaps = 24/166 (14%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F ++S+V H L + G C+ G + ++V E++ + L+ L + G V + W ++ Sbjct 378 FQAEVDIISRVHHRFLVSLVGYCIAGGQRMLVYEFLPNDTLEFHLHGKSGKV-LDWPTRL 436 Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 +A A L+YL ++H ++ NILL S K++D GL LS+ Sbjct 437 KIALGSAKGLAYLHEDCHPRIIHRDIKASNILLDE-------SFEAKVAD--FGLAKLSQ 487 Query 770 EERVE---RI----PWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + RI +LAPE G L+ D + FG LLE+ Sbjct 488 DNVTHVSTRIMGTFGYLAPEYASSG--KLTDRSDVFSFGVMLLELV 531 >sp|Q9SGY7|PEK11_ARATH Putative proline-rich receptor-like protein kinase PERK11 OS=Arabidopsis thaliana OX=3702 GN=PERK11 PE=2 SV=2 Length=718 Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 88/289 (30%), Positives = 137/289 (47%), Gaps = 39/289 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG C G+ VA+K LK+ +R +K E++I+ ++H H++ Sbjct 376 VGEGGFG-----CVYKGILFEGKPVAIKQLKSVSAEGYRE-FKAEVEIISRVHHRHLVSL 429 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLHAQ-- 1017 G C E+ L+ E+VP +L +L ++ + ++ + A +G+AYLH Sbjct 430 VGYC--ISEQHRFLIYEFVPNNTLDYHLHGKNLPVLEWSRRVRIAIGAAKGLAYLHEDCH 487 Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075 IHRD+ + N+LLD++ ++ DFGLA+ + R G F Y APE Sbjct 488 PKIIHRDIKSSNILLDDEFEAQVADFGLARLNDTAQSHISTRVMG---TFGYLAPEYASS 544 Query 1076 YKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 K SDV+SFGV L EL+T D+SQ P L+ A+ RL E +E+G+ Sbjct 545 GKLTDRSDVFSFGVVLLELITGRKPVDTSQ--PLGEESLVEWAR-----PRLIEAIEKGD 597 Query 1133 -------RLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILKT 1171 RL D EVY +++ +C A RP ++ L T Sbjct 598 ISEVVDPRLEN-DYVESEVYKMIETAASCVRHSALKRPRMVQVVRALDT 645 Score = 42.7 bits (99), Expect = 0.022, Method: Compositional matrix adjust. Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 21/184 (11%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F ++S+V H HL + G C+ ++ E+V + LD L + V + W ++ Sbjct 411 FKAEVEIISRVHHRHLVSLVGYCISEQHRFLIYEFVPNNTLDYHLHGKNLPV-LEWSRRV 469 Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALS 768 +A A L+YL ++H ++ NILL A+ ++D G+ L + Sbjct 470 RIAIGAAKGLAYLHEDCHPKIIHRDIKSSNILLDDEFEAQ-------VADFGLARLNDTA 522 Query 769 REERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + R+ +LAPE G L+ D + FG LLE+ G P+ + P +E Sbjct 523 QSHISTRVMGTFGYLAPEYASSGK--LTDRSDVFSFGVVLLEL-ITGRKPVDTSQPLGEE 579 Query 825 HFYQ 828 + Sbjct 580 SLVE 583 >sp|Q55D99|PAKA_DICDI Serine/threonine-protein kinase pakA OS=Dictyostelium discoideum OX=44689 GN=pakA PE=1 SV=1 Length=1197 Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 62/235 (26%), Positives = 117/235 (50%), Gaps = 30/235 (13%) Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE 925 LT P L D+++++ DP K+ I +GEG G+V ++ N T + Sbjct 890 LTDEPPVTLNDLISLD------DP----KKIYYNINKIGEGGAGEV----FEAINSRTNQ 935 Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 +A+K +K Q+ EI +++ HE+I++Y E L + ME++ G Sbjct 936 TIAIKKMKLKA--QNLKTVINEIGMMKNSNHENIVQYIDSYIVADE--LWVAMEFMSGGC 991 Query 986 LRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 L + L ++ + +Q+ Q++ G+ Y+H + IHRD+ + N+L+ + +K+ DF Sbjct 992 LTEVLDQYRDIQLNESQIAFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADF 1051 Query 1043 GLAKAVPEGHEYYRVREDGDSPV---FWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 G A + + +R++ +S V +W APE ++ + + DVWS G+ E+ Sbjct 1052 GYAAQLTQ------IRQERNSVVGTPYWMAPELIRGNNYDFKVDVWSLGIMTREM 1100 Score = 39.7 bits (91), Expect = 0.24, Method: Compositional matrix adjust. Identities = 31/105 (30%), Positives = 48/105 (46%), Gaps = 14/105 (13%) Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS-REER 772 V Q++ L Y+ N +H ++ NIL+ G + IKL+D G R+ER Sbjct 1012 VCQEVLRGLEYIHKFNRIHRDIKSDNILI-------GANGEIKLADFGYAAQLTQIRQER 1064 Query 773 VERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 + W+APE + G N+ +D W G E+ +GE P Sbjct 1065 NSVVGTPYWMAPELIRG--NNYDFKVDVWSLGIMTREMA-EGEPP 1106 >sp|P06782|SNF1_YEAST Carbon catabolite-derepressing protein kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SNF1 PE=1 SV=1 Length=633 Score = 90.9 bits (224), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 78/220 (35%), Positives = 108/220 (49%), Gaps = 19/220 (9%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGP 938 NP S +D H + ++ LGEG FGKV L Y T TG+ VA+K + K Sbjct 41 NPKSSLADGA--HIGNYQIVKTLGEGSFGKVKL-AYHTT---TGQKVALKIINKKVLAKS 94 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGL 997 + ++EI LR L H HIIK + + E + +V+EY L DY+ R + Sbjct 95 DMQGRIEREISYLRLLRHPHIIKLYDVIKSKDE--IIMVIEYAG-NELFDYIVQRDKMSE 151 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + F QQI + Y H +HRDL N+LLD VKI DFGL+ + +G+ + Sbjct 152 QEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGN---FL 208 Query 1058 REDGDSPVFWYAPECLKEYKFYYA--SDVWSFGVTLYELL 1095 + SP + APE + K Y DVWS GV LY +L Sbjct 209 KTSCGSPNY-AAPEVISG-KLYAGPEVDVWSCGVILYVML 246 Score = 41.6 bits (96), Expect = 0.047, Method: Compositional matrix adjust. Identities = 55/241 (23%), Positives = 98/241 (41%), Gaps = 30/241 (12%) Query 638 RVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 +V LK+++ + D+ S + + H H+ ++ V E IMV EY + Sbjct 80 KVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNEL 139 Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 D ++R++ A + QQ+ SA+ Y +VH ++ N+LL Sbjct 140 FDYIVQRDKMSEQEARRFF--QQIISAVEYCHRHKIVHRDLKPENLLLDE-------HLN 190 Query 755 IKLSDPGVGLGALSREERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATL-LEIC 808 +K++D GL + + + + APE + G + +D W G L + +C Sbjct 191 VKIAD--FGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYVMLC 247 Query 809 ----FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 FD E+ P ++ + LP+ P A L + L P R S I++ Sbjct 248 RRLPFDDESI-----PVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQ 302 Query 865 D 865 D Sbjct 303 D 303 >sp|O94168|SNF1_CANTR Carbon catabolite-derepressing protein kinase OS=Candida tropicalis OX=5482 GN=SNF1 PE=3 SV=1 Length=619 Score = 90.9 bits (224), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 77/219 (35%), Positives = 109/219 (50%), Gaps = 18/219 (8%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQ 939 P P +P RY + I+ LGEG FGKV L + GTG+ VA+K + K Sbjct 38 PIDPNVNPANRIGRY-QIIKTLGEGSFGKVKL----AQHVGTGQKVALKIINRKTLAKSD 92 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLA 998 + ++EI LR L H HIIK + + E + +V+E+ L DY+ R + Sbjct 93 MQGRVEREISYLRLLRHPHIIKLYDVIKSKDE--IIMVIEFAG-KELFDYIVQRGKMPED 149 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 + F QQI + Y H +HRDL N+LLD+ VKI DFGL+ + +G+ ++ Sbjct 150 EARRFFQQIIAAVEYCHRHKIVHRDLKPENLLLDDQLNVKIADFGLSNIMTDGN---FLK 206 Query 1059 EDGDSPVFWYAPECLKEYKFYYA--SDVWSFGVTLYELL 1095 SP + APE + K Y DVWS GV LY +L Sbjct 207 TSCGSPNY-AAPEVISG-KLYAGPEVDVWSSGVILYVML 243 Score = 37.4 bits (85), Expect = 0.88, Method: Compositional matrix adjust. Identities = 51/241 (21%), Positives = 92/241 (38%), Gaps = 22/241 (9%) Query 634 GQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 G +V LK+++ + D+ S + + H H+ ++ V E IMV E+ Sbjct 73 GTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEFA 132 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 D + +RG +P QQ+ +A+ Y +VH ++ N+LL Sbjct 133 GKELFDYIV--QRGKMPEDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLLL-------D 183 Query 751 TSPFIKLSDPGVGLGALSREERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATLL 805 +K++D GL + + + + APE + G + +D W G +L Sbjct 184 DQLNVKIAD--FGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSSGV-IL 239 Query 806 EICFDGEAPLQSR-SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + G P P+ + + LP P L ++ L P R + I+ Sbjct 240 YVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSPGAKHLLTRMLVVNPLNRITIHEIME 299 Query 865 D 865 D Sbjct 300 D 300 >sp|B5DE93|CDK12_XENTR Cyclin-dependent kinase 12 OS=Xenopus tropicalis OX=8364 GN=cdk12 PE=2 SV=1 Length=1239 Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 67/215 (31%), Positives = 103/215 (48%), Gaps = 37/215 (17%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958 +GEG +G+V Y + TGE+VA+K ++ D + G+ +EI ILR L H+ Sbjct 716 IGEGTYGQV----YKAKDKDTGELVALKKVRLD---NEKEGFPITAIREIKILRQLIHKS 768 Query 959 IIKYKGCCEDQGEK--------SLQLVMEYVPLGSLRDYLPRHSIGLAQ-----LLLFAQ 1005 ++ K D+ + + LV EY+ D + GL Q + F + Sbjct 769 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMD----HDLMGLLESGLVQFSEDHIKSFMK 824 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK--AVPEGHEYYRVREDGDS 1063 Q+ EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ + E Y Sbjct 825 QLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYSSEESRPYT-----NKV 879 Query 1064 PVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096 WY P L E ++ A DVWS G L EL T Sbjct 880 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFT 914 Score = 37.0 bits (84), Expect = 1.5, Method: Compositional matrix adjust. Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 16/129 (12%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILL 742 +V EY++H D+ E G V + + + +QL L Y KN +H ++ NILL Sbjct 794 LVFEYMDH---DLMGLLESGLVQFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILL 850 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKW 798 G IKL+D G+ S E R ++ W P L G + A+D W Sbjct 851 NNSGQ-------IKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVW 903 Query 799 GFGATLLEI 807 G L E+ Sbjct 904 SCGCILGEL 912 >sp|Q9LSL5|LRK92_ARATH L-type lectin-domain containing receptor kinase IX.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK92 PE=1 SV=1 Length=675 Score = 91.3 bits (225), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 71/211 (34%), Positives = 105/211 (50%), Gaps = 33/211 (16%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LGEG FG V Y+ MVAVK L D Q ++ + E+ I+ L H +++ Sbjct 354 RKLGEGGFGAV----YEGNLKEINTMVAVKKLSGDS-RQGKNEFLNEVKIISKLRHRNLV 408 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------PRHSIGLAQLLLFAQQICE 1009 + G C ++ E L+ E VP GSL +L R+ IGL + Sbjct 409 QLIGWCNEKNE--FLLIYELVPNGSLNSHLFGKRPNLLSWDIRYKIGLG--------LAS 458 Query 1010 GMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 + YLH Q +HRD+ A N++LD++ VK+GDFGLA+ + HE G + F Sbjct 459 ALLYLHEEWDQCVLHRDIKASNIMLDSEFNVKLGDFGLARLM--NHE-LGSHTTGLAGTF 515 Query 1067 WY-APECLKEYKFYYASDVWSFGVTLYELLT 1096 Y APE + + SD++SFG+ L E++T Sbjct 516 GYMAPEYVMKGSASKESDIYSFGIVLLEIVT 546 >sp|Q9GN62|PAR4_CAEEL Serine/threonine-protein kinase par-4 OS=Caenorhabditis elegans OX=6239 GN=par-4 PE=1 SV=2 Length=617 Score = 90.9 bits (224), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 76/240 (32%), Positives = 122/240 (51%), Gaps = 21/240 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW---KQEIDILRTLYHEHI 959 +G G +GKV C D T AVK +K D + +GW + E+ ILR + H ++ Sbjct 189 IGTGSYGKVK-ECIDMY---TLTRRAVKIMKYDKLRKITNGWENIRSEMSILRRMNHRNV 244 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMAYL 1014 IK + + +V EY +GS++ L R +IG + + ++C+G+ YL Sbjct 245 IKLIEIFNIPAKGKVYMVFEYC-IGSVQQLLDMEPARRLTIGESHAIFI--ELCQGLNYL 301 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL- 1073 H++ H+D+ N+L+ D VKI DFG+A+ + R + +P F PEC+ Sbjct 302 HSKRVSHKDIKPGNLLVSIDFTVKICDFGVAEQINLFQRDGRCTKVNGTPKFQ-PPECIY 360 Query 1074 KEYKFY--YASDVWSFGVTLYELLTHCDSSQSPP-TKFLELIGIAQGQM-TVLRLTELLE 1129 + F+ Y +D+WS GVTLY L++ + P K E IG QM T ++LT+ L+ Sbjct 361 GNHDFFDGYKADMWSAGVTLYNLVSGKYPFEKPVLLKLYECIGTEPLQMPTNVQLTKDLQ 420 >sp|E1BK52|STK10_BOVIN Serine/threonine-protein kinase 10 OS=Bos taurus OX=9913 GN=STK10 PE=3 SV=3 Length=966 Score = 91.7 bits (226), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 60/200 (30%), Positives = 105/200 (53%), Gaps = 17/200 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +LG+G FGKV Y N TG + A K ++ + + + EI+IL T H +I+K Sbjct 41 ELGDGAFGKV----YKAKNKETGALAAAKVIETN-SEEELEDYIVEIEILATCDHPYIVK 95 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019 G G+ L +++E+ P G++ + GL Q+ + +Q+ E + +LH + Sbjct 96 LLGAYYYDGK--LWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALTFLHGKKI 153 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP-----ECLK 1074 IHRDL A NVL+ + +++ DFG++ + + + R+ +W AP E +K Sbjct 154 IHRDLKAGNVLMTLEGDIRLADFGVS---AKNLKTLQKRDSFIGTPYWMAPEVVMCETMK 210 Query 1075 EYKFYYASDVWSFGVTLYEL 1094 + + Y +D+WS G+TL E+ Sbjct 211 DTPYDYKADIWSLGITLIEM 230 Score = 41.6 bits (96), Expect = 0.056, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 47/103 (46%), Gaps = 14/103 (14%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV---GLGALSR 769 VV +Q+ AL++L K ++H ++ N+L+ G I+L+D GV L L + Sbjct 136 VVCRQMLEALTFLHGKKIIHRDLKAGNVLMTLEG-------DIRLADFGVSAKNLKTLQK 188 Query 770 EERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808 + P W+APE C D W G TL+E+ Sbjct 189 RDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMA 231 >sp|Q28DZ1|IKKA_XENTR Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Xenopus tropicalis OX=8364 GN=chuk PE=2 SV=1 Length=743 Score = 91.3 bits (225), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 68/206 (33%), Positives = 99/206 (48%), Gaps = 24/206 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V LY N TGE+ A+K+ + + +++ W QEI I++ L H +++K Sbjct 21 LGTGGFGNVCLY----QNRETGELKAIKSCRLELSMKNKERWCQEIQIMKRLNHPNVVK- 75 Query 963 KGCCEDQGEKSL------QLVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMA 1012 CE E L MEY G LR L P + GL +Q+L I G+ Sbjct 76 --ACEVPPEMDFLVNDVPHLAMEYCAGGDLRKLLNKPENCCGLKESQVLNLMSDIGSGIQ 133 Query 1013 YLHAQHYIHRDLAARNVLLD--NDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH + IHRDL N++L N + V KI D G AK + +G + + + A Sbjct 134 YLHEKRIIHRDLKPENIVLQECNGKTVHKIIDLGYAKDLDQG----SLCTSFVGTLQYLA 189 Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095 PE + + D WSFG ++E + Sbjct 190 PELFENKPYSVTVDYWSFGTMVFECI 215 >sp|Q9CAH1|Y1725_ARATH Putative receptor-like protein kinase At1g72540 OS=Arabidopsis thaliana OX=3702 GN=At1g72540 PE=2 SV=1 Length=450 Score = 89.7 bits (221), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 76/211 (36%), Positives = 103/211 (49%), Gaps = 19/211 (9%) Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTL 954 K LGEG FG+V + D G + VAVKALK + G HR W E+ IL L Sbjct 84 FSKYNFLGEGGFGEVYKGFVDDSLKTGLKDQPVAVKALKREGGQGHRE-WLAEVIILGQL 142 Query 955 YHEHIIKYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL------AQLLLFAQQI 1007 H H++ G CCED LV EY+ G+L D+L + G ++LL A Sbjct 143 KHPHLVNLVGYCCEDDER---LLVYEYMERGNLEDHLFQKYGGALPWLTRVKILLGA--- 196 Query 1008 CEGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 +G+ +LH Q I+RD N+LL +D K+ DFGLA E + + + Sbjct 197 AKGLEFLHKQEKPVIYRDFKPSNILLSSDFSSKLSDFGLATDGSEEEDSNFTKSVMGTEG 256 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 + APE + SDV+SFGV L E+LT Sbjct 257 YA-APEYISAGNLTTMSDVFSFGVVLLEMLT 286 Score = 60.1 bits (144), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 63/241 (26%), Positives = 104/241 (43%), Gaps = 52/241 (22%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719 ++ Q+ H HL + G C E ++V EY+E G L D ++ G +P ++ + A Sbjct 138 ILGQLKHPHLVNLVGYCCEDDERLLVYEYMERGNLEDHLFQKYGGALPWLTRVKILLGAA 197 Query 720 SALSYL--ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER----- 772 L +L + K +++ + NILL+ ++ +S KLSD G+ E+ Sbjct 198 KGLEFLHKQEKPVIYRDFKPSNILLS----SDFSS---KLSDFGLATDGSEEEDSNFTKS 250 Query 773 -VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 + + APE + G +L+T D + FG LLE+ L +R EK + QR Sbjct 251 VMGTEGYAAPEYISAG--NLTTMSDVFSFGVVLLEM-------LTARKAVEK-YRAQRGR 300 Query 832 RLPEPSCPQL--------------------------ATLTSQCLTYEPTQRPSFRTILRD 865 L E + P L A L QCL++ P RP+ T+++ Sbjct 301 NLVEWARPMLKDPNKLERIIDPSLEGKYSVEGIRKAAALAYQCLSHNPKSRPTMTTVVKT 360 Query 866 L 866 L Sbjct 361 L 361 >sp|Q02111|KPCT_MOUSE Protein kinase C theta type OS=Mus musculus OX=10090 GN=Prkcq PE=1 SV=1 Length=707 Score = 90.9 bits (224), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 68/209 (33%), Positives = 103/209 (49%), Gaps = 23/209 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI-LRTLYHEHIIK 961 LG+G FGKV L + TN + A+KALK D ++ + +L EH Sbjct 386 LGKGSFGKVFLAEFKRTN----QFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFL 441 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 C Q +++L VMEY+ G L ++ H L++ +A ++ G+ +LH++ + Sbjct 442 THMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEVILGLQFLHSKGIV 501 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WYAPECLKE 1075 +RDL N+LLD D +KI DFG+ K G D + F + APE L Sbjct 502 YRDLKLDNILLDRDGHIKIADFGMCKENMLG--------DAKTNTFCGTPDYIAPEILLG 553 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 K+ ++ D WSFGV +YE+L QSP Sbjct 554 QKYNHSVDWWSFGVLVYEMLI----GQSP 578 >sp|B3NS99|PTK7_DROER Tyrosine-protein kinase-like otk OS=Drosophila erecta OX=7220 GN=otk PE=3 SV=1 Length=1033 Score = 91.3 bits (225), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 62/256 (24%), Positives = 122/256 (48%), Gaps = 31/256 (12%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 ++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY G Sbjct 781 QLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPH--YMVLEYTDWG 838 Query 985 SLRDYLPRHS---------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029 L+ +L + + +Q+L A QI GM ++ + HRDLA RN Sbjct 839 DLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRNC 898 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 ++ ++ +VK+ L K EY++ R + P+ W APEC++E ++ SD++++GV Sbjct 899 VISSEFIVKVSYPALCKD-KYSREYHKHR-NTLLPIRWLAPECIQEDEYTTKSDIFAYGV 956 Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149 ++EL +++ P + + + Q L + + P + ++ Sbjct 957 VVWELFNQ--ATKLPHEELTNEQVVQRSQAGSLEWS----------VAEATPDSLREILL 1004 Query 1150 NCWETEASFRPTFENL 1165 +CW + RP+F L Sbjct 1005 SCWVSNPKERPSFSQL 1020 Score = 55.5 bits (132), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 65/262 (25%), Positives = 104/262 (40%), Gaps = 44/262 (17%) Query 636 ELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 E V++K L+ + A F L+ +SH + + G+C + MV EY + G Sbjct 780 EQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDWGD 839 Query 695 LDVWLRRERGHVPMAWK-------------MVVAQQLASALSYLENKNLVHGNVCGRNIL 741 L +L G V A + VA Q+A + + H ++ RN + Sbjct 840 LKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRNCV 899 Query 742 LARLGLAEGTSPFI-KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAM 795 + +S FI K+S P + SRE R I WLAPEC+ + +T Sbjct 900 I--------SSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQ--EDEYTTKS 949 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQH------RLPEPSCPQLATLTS 846 D + +G + E+ F+ L P E+ E QR + E + L + Sbjct 950 DIFAYGVVVWEL-FNQATKL----PHEELTNEQVVQRSQAGSLEWSVAEATPDSLREILL 1004 Query 847 QCLTYEPTQRPSFRTILRDLTR 868 C P +RPSF + L++ Sbjct 1005 SCWVSNPKERPSFSQLGAALSK 1026 >sp|Q9M2S4|LRKS4_ARATH L-type lectin-domain containing receptor kinase S.4 OS=Arabidopsis thaliana OX=3702 GN=LECRKS4 PE=2 SV=1 Length=684 Score = 90.9 bits (224), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 75/221 (34%), Positives = 106/221 (48%), Gaps = 25/221 (11%) Query 889 PTVFHKRYLKKIRD-------LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 P F R LKK + LG G FGKV Y G+ E VAVK + + R Sbjct 331 PHRFSYRELKKATNGFGDKELLGSGGFGKV----YKGKLPGSDEFVAVKRISHESRQGVR 386 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGL 997 + E+ + L H ++++ G C + + L LV +++P GSL YL P + Sbjct 387 E-FMSEVSSIGHLRHRNLVQLLGWCRRRDD--LLLVYDFMPNGSLDMYLFDENPEVILTW 443 Query 998 AQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 Q + + G+ YLH Q IHRD+ A NVLLD++ ++GDFGLAK G + Sbjct 444 KQRFKIIKGVASGLLYLHEGWEQTVIHRDIKAANVLLDSEMNGRVGDFGLAKLYEHGSDP 503 Query 1055 YRVREDGDSPVFWY-APECLKEYKFYYASDVWSFGVTLYEL 1094 R G F Y APE K K ++DV++FG L E+ Sbjct 504 GATRVVG---TFGYLAPELTKSGKLTTSTDVYAFGAVLLEV 541 Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 65/255 (25%), Positives = 111/255 (44%), Gaps = 43/255 (17%) Query 582 HRVDQKEITQLSH-------LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 HR +E+ + ++ LG G VY+G+L PG D Sbjct 332 HRFSYRELKKATNGFGDKELLGSGGFGKVYKGKL--------------------PGSD-- 369 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 E V ++ S + F S + + H +L + G C R + ++V +++ +G Sbjct 370 -EFVAVKRISHESRQGVR-EFMSEVSSIGHLRHRNLVQLLGWCRRRDDLLLVYDFMPNGS 427 Query 695 LDVWLRRERGHVPMAWK--MVVAQQLASALSYLE---NKNLVHGNVCGRNILL-ARLGLA 748 LD++L E V + WK + + +AS L YL + ++H ++ N+LL + + Sbjct 428 LDMYLFDENPEVILTWKQRFKIIKGVASGLLYLHEGWEQTVIHRDIKAANVLLDSEMNGR 487 Query 749 EGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 G KL + G GA V +LAPE G L+T+ D + FGA LLE+ Sbjct 488 VGDFGLAKLYEHGSDPGA---TRVVGTFGYLAPELTKSG--KLTTSTDVYAFGAVLLEVA 542 Query 809 FDGEAPLQSRSPSEK 823 G P+++ + E+ Sbjct 543 C-GRRPIETSALPEE 556 >sp|Q9H4B4|PLK3_HUMAN Serine/threonine-protein kinase PLK3 OS=Homo sapiens OX=9606 GN=PLK3 PE=1 SV=2 Length=646 Score = 90.5 bits (223), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 70/225 (31%), Positives = 109/225 (48%), Gaps = 14/225 (6%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933 LA + T +P +DP + YLK R LG+G F + CY+ T+ TG AVK + Sbjct 41 LAGLPTSDPGRLITDPRS-GRTYLKG-RLLGKGGFAR----CYEATDTETGSAYAVKVIP 94 Query 934 AD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YL 990 P R EI++ R L H HI+++ ED ++ + +E SL + Sbjct 95 QSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDA--DNIYIFLELCSRKSLAHIWK 152 Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 RH++ ++ + +QI G+ YLH + +HRDL N + + +K+GDFGLA + Sbjct 153 ARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEP 212 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 + R + +P + APE L +DVWS G +Y LL Sbjct 213 PEQ--RKKTICGTPNY-VAPEVLLRQGHGPEADVWSLGCVMYTLL 254 >sp|Q54TH6|Y9863_DICDI Probable serine/threonine-protein kinase DDB_G0281745 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0281745 PE=3 SV=1 Length=597 Score = 90.5 bits (223), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 73/279 (26%), Positives = 127/279 (46%), Gaps = 36/279 (13%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 ++G G +G VSL + G VA+K L + + ++E+ IL+ + H I++ Sbjct 339 EIGSGKYGSVSLGYW------LGTPVAIKKLHEN-NEETEILVQRELQILKEIRHPQIVQ 391 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019 + G ++ ++ + ++ E++ G L D L I L + L + I + +LHA+ Sbjct 392 FLGVSRNEKDE-IHIITEFMDGGDLFDALIFGDIPLTWKEKLRISLDIAQSCRFLHARGI 450 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPE--GHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL ++N+LL +R K+ D GLA+ E Y V + W APE + Sbjct 451 LHRDLKSQNILLSTNRRAKLCDLGLARMFEERINKRYTCVGTE-----IWMAPEVCLDQS 505 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + A DV+SFG+ L E++T + P + A L++ P Sbjct 506 YSTAVDVFSFGIVLVEIITEKIPDERFPQHRFQFDAPA-----------FLKK-----VP 549 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 +CP + L +C + RP+F I +L T+ Y Sbjct 550 KECPPDFSKLCVDCTKYNPKERPSF---IKVLDTIQNIY 585 Score = 69.3 bits (168), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 62/249 (25%), Positives = 116/249 (47%), Gaps = 40/249 (16%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDV 697 V +K L ++ + + ++ ++ H + GV + I ++TE+++ G D+ Sbjct 358 VAIKKLHENNEETEILVQRELQILKEIRHPQIVQFLGVSRNEKDEIHIITEFMDGG--DL 415 Query 698 WLRRERGHVPMAWK--MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 + G +P+ WK + ++ +A + +L + ++H ++ +NILL+ T+ Sbjct 416 FDALIFGDIPLTWKEKLRISLDIAQSCRFLHARGILHRDLKSQNILLS-------TNRRA 468 Query 756 KLSDPGVGLGALSREERVERI-------PWLAPE-CLPGGANSLSTAMDKWGFGATLLEI 807 KL D G+ A EER+ + W+APE CL S STA+D + FG L+EI Sbjct 469 KLCDLGL---ARMFEERINKRYTCVGTEIWMAPEVCL---DQSYSTAVDVFSFGIVLVEI 522 Query 808 CFDGEAPLQSRSPSEK--EHFYQRQ-----HRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 + + P E+ +H +Q ++P+ P + L C Y P +RPSF Sbjct 523 -------ITEKIPDERFPQHRFQFDAPAFLKKVPKECPPDFSKLCVDCTKYNPKERPSFI 575 Query 861 TILRDLTRL 869 +L + + Sbjct 576 KVLDTIQNI 584 >sp|Q00372|SNF1_CANGA Carbon catabolite-derepressing protein kinase OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=SNF1 PE=3 SV=2 Length=612 Score = 90.5 bits (223), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 73/201 (36%), Positives = 102/201 (51%), Gaps = 17/201 (8%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHE 957 ++ LGEG FGKV L Y T TG+ VA+K + K + ++EI LR L H Sbjct 42 VKTLGEGSFGKVKL-AYHVT---TGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHP 97 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHA 1016 HIIK + + E + +V+EY L DY+ R+ + + F QQI + Y H Sbjct 98 HIIKLYDVIKSKDE--IIMVIEYAG-NELFDYIVQRNKMSEQEARRFFQQIISAVEYCHR 154 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL N+LLD VKI DFGL+ + +G+ ++ SP + APE + Sbjct 155 HKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGN---FLKTSCGSPNY-AAPEVISG- 209 Query 1077 KFYYA--SDVWSFGVTLYELL 1095 K Y DVWS GV LY +L Sbjct 210 KLYAGPEVDVWSCGVILYVML 230 Score = 42.4 bits (98), Expect = 0.029, Method: Compositional matrix adjust. Identities = 64/289 (22%), Positives = 116/289 (40%), Gaps = 39/289 (13%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP--- 646 ++S L G+R Y+ V+ G+ GK+ + G+ +V LK+++ Sbjct 25 NKVSSLADGSRVGNYQ---IVKTLGEGSFGKVKLAYHVTTGQ------KVALKIINKKVL 75 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 + D+ S + + H H+ ++ V E IMV EY + D ++R + Sbjct 76 AKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRNKMSE 135 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 A + QQ+ SA+ Y +VH ++ N+LL +K++D GL Sbjct 136 QEARRFF--QQIISAVEYCHRHKIVHRDLKPENLLLDE-------HLNVKIAD--FGLSN 184 Query 767 LSREERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATL-LEIC----FDGEAPLQ 816 + + + + APE + G + +D W G L + +C FD E+ Sbjct 185 IMTDGNFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYVMLCRRLPFDDESI-- 241 Query 817 SRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 P ++ + LP+ P + L + L P R S I++D Sbjct 242 ---PVLFKNISNGVYTLPKFLSPGASDLIKRMLIVNPLNRISIHEIMQD 287 >sp|Q556S2|PAKH_DICDI Serine/threonine-protein kinase pakH OS=Dictyostelium discoideum OX=44689 GN=pakH-1 PE=3 SV=1 Length=513 Score = 90.1 bits (222), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 60/200 (30%), Positives = 95/200 (48%), Gaps = 25/200 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA----DCGPQHRSGWKQEIDILRTLYHEH 958 LGEG FG V Y + + +A+K + D P + EI IL+ + + Sbjct 48 LGEGSFGSV----YRAIHKSSNTSIAIKEFEIFEANDVEPISK-----EIQILKKCNNPY 98 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA----QLLLFAQQICEGMAYL 1014 ++ Y G + + ++M+Y L S D + SIG ++ L QQ G+ YL Sbjct 99 VVSYFGSIMLKNK--YWILMDYCSLSSFNDIM--QSIGKTFKEKEISLILQQSLLGLVYL 154 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H++ IHRD+ + N+LLD VKI DFG+++ + + +P +W APE L Sbjct 155 HSKQIIHRDIKSANILLDETGQVKIADFGVSQQI---QSTFSKGSIAGTP-YWMAPEILN 210 Query 1075 EYKFYYASDVWSFGVTLYEL 1094 + + DVWS G+ EL Sbjct 211 QTDYNNKIDVWSLGIVAIEL 230 Score = 54.7 bits (130), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 39/151 (26%), Positives = 68/151 (45%), Gaps = 17/151 (11%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSRE 770 ++ QQ L YL +K ++H ++ NILL G +K++D GV + + + Sbjct 142 LILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQ-------VKIADFGVSQQIQSTFSK 194 Query 771 ERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 + P W+APE L + +D W G +E+ DGE PL +P + R Sbjct 195 GSIAGTPYWMAPEIL--NQTDYNNKIDVWSLGIVAIELA-DGEPPLSEVNPMRAMYMIGR 251 Query 830 Q----HRLPEPSCPQLATLTSQCLTYEPTQR 856 + + P+ P+ + +CLT + +R Sbjct 252 RPPPTFKDPKKWSPEFVSFVDKCLTKDINER 282 >sp|Q869N2|PAKB_DICDI Serine/threonine-protein kinase pakB OS=Dictyostelium discoideum OX=44689 GN=pakB PE=1 SV=1 Length=852 Score = 90.9 bits (224), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 85/292 (29%), Positives = 138/292 (47%), Gaps = 38/292 (13%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DPT K + + +GEG G+V + TN+ VA+K K Q+ E Sbjct 564 DPT---KLFGEGSTKIGEGAAGEVFVVTQLKTNN----KVAIK--KMPLNQQNMKLIVTE 614 Query 948 IDILRTLYHEHIIKYKGC--CEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGL--AQLLL 1002 I I+++ H++II Y D SL + ME++ G L + L + +S+ L AQ+ Sbjct 615 IGIMKSCRHQNIIDYIDSYLVGD----SLWVAMEFMGGGCLTEILEQFNSVKLVEAQIAY 670 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 + +G+AY+H+QH IHRD+ + N+LL +D VK+ DFG A + + + RV G Sbjct 671 VCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAAQLTKSKQ-KRVTIVGT 729 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQMTV 1121 +W APE ++ + D+WS G+ E+ S PP + L LI T Sbjct 730 P--YWMAPELIRGQNYDRKVDIWSLGIMAMEMAESEPPYMSFPPLRALFLI-------TT 780 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKT 1171 + +L ++ +K + +K C + + RP + L+ P LKT Sbjct 781 KGIPDLKDQ-------NKWSDDFKDFVKKCLDKDVENRPEAKVLLNHPFLKT 825 Score = 35.0 bits (79), Expect = 5.8, Method: Compositional matrix adjust. Identities = 29/111 (26%), Positives = 52/111 (47%), Gaps = 14/111 (13%) Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREER 772 V + L+Y+ +++ +H ++ NILL G+ +KL+D G S+++R Sbjct 671 VCAETLKGLAYIHSQHRIHRDIKSDNILL-------GSDGSVKLADFGYAAQLTKSKQKR 723 Query 773 VERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 V + W+APE + G + +D W G +E+ + E P S P Sbjct 724 VTIVGTPYWMAPELIRG--QNYDRKVDIWSLGIMAMEMA-ESEPPYMSFPP 771 >sp|Q92918|M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 OS=Homo sapiens OX=9606 GN=MAP4K1 PE=1 SV=1 Length=833 Score = 90.9 bits (224), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 63/214 (29%), Positives = 112/214 (52%), Gaps = 17/214 (8%) Query 888 DPTVFHKR---YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 DP +F++ + ++ LG G +G+V + + +G++VA+K +K + S Sbjct 5 DPDIFNRDPRDHYDLLQRLGGGTYGEV----FKARDKVSGDLVALKMVKMEPD-DDVSTL 59 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLF 1003 ++EI IL+T H +I+ Y G + L + ME+ GSL+D Y S+ Q+ Sbjct 60 QKEILILKTCRHANIVAYHGSY--LWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYV 117 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 +++ +G+AYLH+Q IHRD+ N+L+++ V++ DFG++ + G R + Sbjct 118 CREVLQGLAYLHSQKKIHRDIKGANILINDAGEVRLADFGISAQI--GATLARRLSFIGT 175 Query 1064 PVFWYAPECLK---EYKFYYASDVWSFGVTLYEL 1094 P +W APE + + D+WS G+T EL Sbjct 176 P-YWMAPEVAAVALKGGYNELCDIWSLGITAIEL 208 Score = 42.7 bits (99), Expect = 0.025, Method: Compositional matrix adjust. Identities = 55/236 (23%), Positives = 94/236 (40%), Gaps = 45/236 (19%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 F+R + L LG GT V++ R +V G V Sbjct 9 FNRDPRDHYDLLQRLGGGTYGEVFKARDKVSGD------------------------LVA 44 Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWL 699 LK++ D + ++ H ++ HG + + + E+ G L D++ Sbjct 45 LKMVKMEPDDDVSTLQKEILILKTCRHANIVAYHGSYLWLQKLWICMEFCGAGSLQDIY- 103 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + G + V +++ L+YL ++ +H ++ G NIL+ G ++L+D Sbjct 104 -QVTGSLSELQISYVCREVLQGLAYLHSQKKIHRDIKGANILINDAG-------EVRLAD 155 Query 760 PGVG--LGA-LSREERVERIP-WLAPE----CLPGGANSLSTAMDKWGFGATLLEI 807 G+ +GA L+R P W+APE L GG N L D W G T +E+ Sbjct 156 FGISAQIGATLARRLSFIGTPYWMAPEVAAVALKGGYNELC---DIWSLGITAIEL 208 >sp|Q9SR05|ANX1_ARATH Receptor-like protein kinase ANXUR1 OS=Arabidopsis thaliana OX=3702 GN=ANX1 PE=1 SV=1 Length=850 Score = 90.9 bits (224), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 67/202 (33%), Positives = 104/202 (51%), Gaps = 21/202 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FGKV Y DGT + VAVK + Q + ++ EI++L L H+H++ Sbjct 523 IGVGGFGKV----YKGVIDGTTK-VAVKKSNPNS-EQGLNEFETEIELLSRLRHKHLVSL 576 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA--- 1016 G C++ GE + LV +Y+ G+LR++L + + + L A G+ YLH Sbjct 577 IGYCDEGGE--MCLVYDYMAFGTLREHLYNTKKPQLTWKRRLEIAIGAARGLHYLHTGAK 634 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE---GHEYYRVREDGDSPVFWYAPECL 1073 IHRD+ N+L+D + + K+ DFGL+K P GH V+ + PE Sbjct 635 YTIIHRDVKTTNILVDENWVAKVSDFGLSKTGPNMNGGHVTTVVK----GSFGYLDPEYF 690 Query 1074 KEYKFYYASDVWSFGVTLYELL 1095 + + SDV+SFGV L+E+L Sbjct 691 RRQQLTEKSDVYSFGVVLFEIL 712 Score = 43.5 bits (101), Expect = 0.016, Method: Compositional matrix adjust. Identities = 60/262 (23%), Positives = 102/262 (39%), Gaps = 27/262 (10%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K +P+ F L+S++ H HL + G C G E +V +Y+ G L Sbjct 541 KVAVKKSNPNSEQGLNEFETEIELLSRLRHKHLVSLIGYCDEGGEMCLVYDYMAFGTLRE 600 Query 698 WLRRERGHVPMAWK--MVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752 L + + WK + +A A L YL ++H +V NIL+ +A+ + Sbjct 601 HLYNTK-KPQLTWKRRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILVDENWVAKVSD 659 Query 753 PFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI----- 807 + + P + G ++ + +L PE L+ D + FG L EI Sbjct 660 FGLSKTGPNMNGGHVTTVVK-GSFGYLDPEYFR--RQQLTEKSDVYSFGVVLFEILCARP 716 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL------------ATLTSQCLTYEPTQ 855 + P + S + +R+ L + P L A +CL + Sbjct 717 ALNPSLPKEQVSLGDWAMNCKRKGNLEDIIDPNLKGKINAECLKKFADTAEKCLNDSGLE 776 Query 856 RPSFRTILRDLT-RLQPHNLAD 876 RP+ +L +L LQ AD Sbjct 777 RPTMGDVLWNLEFALQLQETAD 798 >sp|Q1PEM5|PERK3_ARATH Proline-rich receptor-like protein kinase PERK3 OS=Arabidopsis thaliana OX=3702 GN=PERK3 PE=2 SV=2 Length=513 Score = 89.7 bits (221), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 68/201 (34%), Positives = 100/201 (50%), Gaps = 18/201 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG V + N+ VAVK LK Q ++ E++I+ ++H +++ Sbjct 189 LGEGGFGFVYKGILNNGNE-----VAVKQLKVGSA-QGEKEFQAEVNIISQIHHRNLVSL 242 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 G C ++ LV E+VP +L +L R ++ + L A +G++YLH Sbjct 243 VGYCIAGAQR--LLVYEFVPNNTLEFHLHGKGRPTMEWSLRLKIAVSSSKGLSYLHENCN 300 Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075 IHRD+ A N+L+D K+ DFGLAK + + + R G F Y APE Sbjct 301 PKIIHRDIKAANILIDFKFEAKVADFGLAKIALDTNTHVSTRVMG---TFGYLAPEYAAS 357 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 K SDV+SFGV L EL+T Sbjct 358 GKLTEKSDVYSFGVVLLELIT 378 Score = 53.9 bits (128), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 48/183 (26%), Positives = 81/183 (44%), Gaps = 27/183 (15%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F +++SQ+ H +L + G C+ G + ++V E+V + L+ L +G M W ++ Sbjct 224 FQAEVNIISQIHHRNLVSLVGYCIAGAQRLLVYEFVPNNTLEFHL-HGKGRPTMEWSLRL 282 Query 713 VVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 +A + LSYL N ++H ++ NIL+ A K++D G+ AL Sbjct 283 KIAVSSSKGLSYLHENCNPKIIHRDIKAANILIDFKFEA-------KVADFGLAKIALDT 335 Query 770 EERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 V +LAPE G L+ D + FG LLE+ + R P + Sbjct 336 NTHVSTRVMGTFGYLAPEYAASG--KLTEKSDVYSFGVVLLEL-------ITGRRPVDAN 386 Query 825 HFY 827 + Y Sbjct 387 NVY 389 >sp|Q9ZT07|RKS1_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase RKS1 OS=Arabidopsis thaliana OX=3702 GN=RKS1 PE=3 SV=3 Length=833 Score = 90.9 bits (224), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 71/202 (35%), Positives = 102/202 (50%), Gaps = 18/202 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V Y E +AVK L + G Q +K E+ ++ L H ++++ Sbjct 521 LGAGGFGPV----YKGVLQNRME-IAVKRLSRNSG-QGMEEFKNEVKLISKLQHRNLVRI 574 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017 GCC + EK LV EY+P SL DY H A+L + + I G+ YLH Sbjct 575 LGCCVELEEK--MLVYEYLPNKSL-DYFIFHEEQRAELDWPKRMEIVRGIARGILYLHQD 631 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL A N+LLD++ + KI DFG+A+ + G++ + APE Sbjct 632 SRLRIIHRDLKASNILLDSEMIPKISDFGMAR-IFGGNQMEGCTSRVVGTFGYMAPEYAM 690 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 E +F SDV+SFGV + E++T Sbjct 691 EGQFSIKSDVYSFGVLMLEIIT 712 Score = 50.8 bits (120), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 45/184 (24%), Positives = 81/184 (44%), Gaps = 20/184 (11%) Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 + + +K L + F L+S++ H +L + G CV E ++V EY+ + Sbjct 536 NRMEIAVKRLSRNSGQGMEEFKNEVKLISKLQHRNLVRILGCCVELEEKMLVYEYLPNKS 595 Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAE 749 LD ++ E + W +M + + +A + YL + ++H ++ NILL Sbjct 596 LDYFIFHEEQRAELDWPKRMEIVRGIARGILYLHQDSRLRIIHRDLKASNILL------- 648 Query 750 GTSPFIKLSDPGVG--LGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGAT 803 + K+SD G+ G E R+ ++APE G S+ + D + FG Sbjct 649 DSEMIPKISDFGMARIFGGNQMEGCTSRVVGTFGYMAPEYAMEGQFSIKS--DVYSFGVL 706 Query 804 LLEI 807 +LEI Sbjct 707 MLEI 710 >sp|P53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 OS=Homo sapiens OX=9606 GN=PLK1 PE=1 SV=1 Length=603 Score = 90.1 bits (222), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 77/267 (29%), Positives = 118/267 (44%), Gaps = 28/267 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960 LG+G F K C++ ++ T E+ A K + P R EI I R+L H+H++ Sbjct 59 LGKGGFAK----CFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVV 114 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G ED + +V+E SL + + R ++ + + +QI G YLH Sbjct 115 GFHGFFEDND--FVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRV 172 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRDL N+ L+ D VKIGDFGLA V E R + +P + APE L + Sbjct 173 IHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGE--RKKTLCGTPN-YIAPEVLSKKGHS 229 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 + DVWS G +Y L L+G + + L+ T L + P Sbjct 230 FEVDVWSIGCIMYTL----------------LVGKPPFETSCLKETYLRIKKNEYSIPKH 273 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLI 1166 L++ +T+ + RPT L+ Sbjct 274 INPVAASLIQKMLQTDPTARPTINELL 300 Score = 43.9 bits (102), Expect = 0.009, Method: Compositional matrix adjust. Identities = 46/211 (22%), Positives = 84/211 (40%), Gaps = 16/211 (8%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+ ++H H+ HG +V E L + L + R + +Q+ Sbjct 103 SIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSL-LELHKRRKALTEPEARYYLRQIV 161 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776 YL ++H R++ L L L E +K+ D G+ ER + + Sbjct 162 LGCQYLHRNRVIH-----RDLKLGNLFLNEDLE--VKIGDFGLATKVEYDGERKKTLCGT 214 Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLP 834 ++APE L +S +D W G + + G+ P ++ E + ++ +P Sbjct 215 PNYIAPEVLSKKGHSFE--VDVWSIGCIMYTLLV-GKPPFETSCLKETYLRIKKNEYSIP 271 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + P A+L + L +PT RP+ +L D Sbjct 272 KHINPVAASLIQKMLQTDPTARPTINELLND 302 >sp|Q54U31|SHKD_DICDI Dual specificity protein kinase shkD OS=Dictyostelium discoideum OX=44689 GN=shkD PE=3 SV=1 Length=744 Score = 90.5 bits (223), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 73/290 (25%), Positives = 128/290 (44%), Gaps = 29/290 (10%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQH 940 P AS P + + LG+G FG V G+ VAVK K Sbjct 262 PKRKASGPPEILPEEIDRTDFLGQGSFGSVY------KGKCRGQEVAVKIPRKQKLSLYE 315 Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS---LRDYLPRHSIGL 997 + ++ E+ I+ ++H +++ + G C G+ +Q+V E L + + L Sbjct 316 LTSFRHEVKIMSKIFHPNVVLFLGACTQSGK--MQIVTELCQTDLEKLLHNDRTKKEFSL 373 Query 998 AQLLLFAQQICEGMAYLHA-QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 + + A+ GM +LH +H DL N+L+D + VK+ DFG ++ + EG E+ Sbjct 374 FRRMQMAKDAALGMNWLHGITRIVHNDLKTANLLVDINLRVKVTDFGFSQ-IKEGEEFQD 432 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 G +P+ W APE + + +DV+SFG+ L+E+LT ++P + Sbjct 433 KAAKG-TPL-WMAPEVMMGNPYNEKADVYSFGIILWEILT----KEAP---------YSH 477 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + + + ER P P + HL++ CW+ RP+F ++ Sbjct 478 HKDYDIFFNAICNEKERPPIPADTLPSLRHLIQTCWDHNPQNRPSFSEIL 527 Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 74/300 (25%), Positives = 126/300 (42%), Gaps = 58/300 (19%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 +EI + LGQG+ +VY+G+ R GQE+ V + P Sbjct 275 EEIDRTDFLGQGSFGSVYKGKCR------------------------GQEVAVKI----P 306 Query 647 SHHDIAL----AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 ++L +F +MS++ H ++ G C + + +VTE + L+ L + Sbjct 307 RKQKLSLYELTSFRHEVKIMSKIFHPNVVLFLGACTQSGKMQIVTELCQTD-LEKLLHND 365 Query 703 RGHVPMAW--KMVVAQQLASALSYLEN-KNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R + +M +A+ A +++L +VH ++ N LL + L +K++D Sbjct 366 RTKKEFSLFRRMQMAKDAALGMNWLHGITRIVHNDLKTAN-LLVDINLR------VKVTD 418 Query 760 PG---VGLGALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G + G +++ + P W+APE + G N + D + FG L EI EAP Sbjct 419 FGFSQIKEGEEFQDKAAKGTPLWMAPEVMMG--NPYNEKADVYSFGIILWEI-LTKEAPY 475 Query 816 QSRSPSEKEHFYQ----RQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + F+ + R P P + P L L C + P RPSF IL L + Sbjct 476 SHHK--DYDIFFNAICNEKERPPIPADTLPSLRHLIQTCWDHNPQNRPSFSEILFRLNEI 533 >sp|Q9VI13|PAK_DROME Serine/threonine-protein kinase Pak OS=Drosophila melanogaster OX=7227 GN=Pak PE=1 SV=1 Length=704 Score = 90.5 bits (223), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 60/203 (30%), Positives = 97/203 (48%), Gaps = 12/203 (6%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 R K+ +G+G G V Y TG VA+K + P+ + EI ++R Sbjct 427 NRKYTKMEKIGQGASGTV----YTAIESSTGMEVAIKQMNLSQQPK-KELIINEILVMRE 481 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013 H +++ Y E L +VMEY+P GSL D + + Q+ +++ + + + Sbjct 482 NKHPNVVNYLDSYLVSEE--LWVVMEYLPGGSLTDVVTETCMDEGQIAAVCREVLQALEF 539 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 LHA IHRD+ + N+LL D VK+ DFG A+ PE + R G +W APE Sbjct 540 LHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPE--QSKRTTMVGTP--YWMAPEV 595 Query 1073 LKEYKFYYASDVWSFGVTLYELL 1095 + ++ D+WS G+ E++ Sbjct 596 VTRKQYGPKVDLWSLGIMAIEMV 618 >sp|Q9SFX0|PBL22_ARATH Probable serine/threonine-protein kinase PBL22 OS=Arabidopsis thaliana OX=3702 GN=PBL22 PE=2 SV=1 Length=381 Score = 88.2 bits (217), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 82/277 (30%), Positives = 131/277 (47%), Gaps = 25/277 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FG V Y D +G++VA+K L D G Q + E+ +L +H +++ Sbjct 81 IGKGGFGSV----YKGRLD-SGQVVAIKQLNPD-GHQGNQEFIVEVCMLSVFHHPNLVTL 134 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHS-IGLAQLLLFAQQICEGMAYLHAQ 1017 G C ++ LV EY+P+GSL D+L P + + + A G+ YLH + Sbjct 135 IGYCTSGAQR--LLVYEYMPMGSLEDHLFDLEPDQTPLSWYTRMKIAVGAARGIEYLHCK 192 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 I+RDL + N+LLD + VK+ DFGLAK P G+ + V + APE Sbjct 193 ISPSVIYRDLKSANILLDKEFSVKLSDFGLAKVGPVGNRTH-VSTRVMGTYGYCAPEYAM 251 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLR----LTELLE 1129 + SD++SFGV L EL++ + S P L+ A+ + + L + L Sbjct 252 SGRLTIKSDIYSFGVVLLELISGRKAIDLSKPNGEQYLVAWARPYLKDPKKFGLLVDPLL 311 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 RG+ R C + + C EA+ RP +++ Sbjct 312 RGKFSKR---CLNYAISITEMCLNDEANHRPKIGDVV 345 Score = 56.6 bits (135), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 81/345 (23%), Positives = 134/345 (39%), Gaps = 69/345 (20%) Query 553 PQPGETSNLIIMRGARASP------RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606 P+ + + I++ G SP R+ +L+ K + + +G+G +VY+G Sbjct 36 PRGTGSKSGILVNGKVNSPKPGGGARSFTFKELA---AATKNFREGNIIGKGGFGSVYKG 92 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS 666 RL D GQ V +K L+P H F ++S Sbjct 93 RL-----------------------DSGQV--VAIKQLNPDGHQGNQEFIVEVCMLSVFH 127 Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAW--KMVVAQQLASALS 723 H +L + G C G + ++V EY+ G L D E P++W +M +A A + Sbjct 128 HPNLVTLIGYCTSGAQRLLVYEYMPMGSLEDHLFDLEPDQTPLSWYTRMKIAVGAARGIE 187 Query 724 YLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERVE-RIPW 778 YL K ++++ ++ NILL + +KLSD G+ +G + V R+ Sbjct 188 YLHCKISPSVIYRDLKSANILLDK-------EFSVKLSDFGLAKVGPVGNRTHVSTRVMG 240 Query 779 LAPECLPGGANS--LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836 C P A S L+ D + FG LLE+ +A S+ E+ + L +P Sbjct 241 TYGYCAPEYAMSGRLTIKSDIYSFGVVLLELISGRKAIDLSKPNGEQYLVAWARPYLKDP 300 Query 837 S-----------------CPQLA-TLTSQCLTYEPTQRPSFRTIL 863 C A ++T CL E RP ++ Sbjct 301 KKFGLLVDPLLRGKFSKRCLNYAISITEMCLNDEANHRPKIGDVV 345 >sp|Q96PY6|NEK1_HUMAN Serine/threonine-protein kinase Nek1 OS=Homo sapiens OX=9606 GN=NEK1 PE=1 SV=2 Length=1258 Score = 90.9 bits (224), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 57/201 (28%), Positives = 102/201 (51%), Gaps = 11/201 (5%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 +++ +GEG FGK L T DG ++ + + + R ++E+ +L + H + Sbjct 6 RLQKIGEGSFGKAILV--KSTEDGRQYVIKEINI-SRMSSKEREESRREVAVLANMKHPN 62 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLH 1015 I++Y+ E+ G SL +VM+Y G L + L Q+L + QIC + ++H Sbjct 63 IVQYRESFEENG--SLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVH 120 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + +HRD+ ++N+ L D V++GDFG+A+ + E R ++ +PE + Sbjct 121 DRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELART---CIGTPYYLSPEICEN 177 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 + SD+W+ G LYEL T Sbjct 178 KPYNNKSDIWALGCVLYELCT 198 >sp|P97377|CDK2_MOUSE Cyclin-dependent kinase 2 OS=Mus musculus OX=10090 GN=Cdk2 PE=1 SV=2 Length=346 Score = 87.8 bits (216), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 65/207 (31%), Positives = 101/207 (49%), Gaps = 15/207 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955 +K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ L Sbjct 4 FQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN 59 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYV--PLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013 H +I+K E L LV E++ L D I L + + Q+ +G+A+ Sbjct 60 HPNIVKLLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAF 117 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072 H+ +HRDL +N+L++ + +K+ DFGLA+A Y + WY APE Sbjct 118 CHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTY----THEVVTLWYRAPEI 173 Query 1073 LKEYKFY-YASDVWSFGVTLYELLTHC 1098 L K+Y A D+WS G E+ C Sbjct 174 LLGCKYYSTAVDIWSLGCIFAEMHLVC 200 Score = 33.9 bits (76), Expect = 8.3, Method: Compositional matrix adjust. Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 12/95 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREER 772 QL L++ + ++H ++ +N+L+ AEG+ IKL+D G+ G+ + Sbjct 110 QLLQGLAFCHSHRVLHRDLKPQNLLIN----AEGS---IKLADFGLARAFGVPVRTYTHE 162 Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 V + + APE L G STA+D W G E+ Sbjct 163 VVTLWYRAPEILLG-CKYYSTAVDIWSLGCIFAEM 196 >sp|B4GBH0|PTK7_DROPE Tyrosine-protein kinase-like otk OS=Drosophila persimilis OX=7234 GN=otk PE=3 SV=1 Length=1035 Score = 90.9 bits (224), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 65/255 (25%), Positives = 120/255 (47%), Gaps = 30/255 (12%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 ++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY G Sbjct 783 QLVLVKALNKVKDEQACQEFRRQLDLLRGISHKGVVRLFGLCREKDPH--YMVLEYTDWG 840 Query 985 SLRDYLPRHS--------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030 L+ +L + + +Q+L A QI GM ++ HRDLA RN + Sbjct 841 DLKQFLLATAGKVNTATATSSPPALTTSQVLAVAYQIARGMDAIYRSRCTHRDLATRNCV 900 Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 + ++ +VK+ L K EY++ R + PV W APEC++E ++ SD++++GV Sbjct 901 ISSEFVVKVSYPALCKD-KYSREYHKHR-NTLLPVRWLAPECIQEDEYTTKSDIFAYGVL 958 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 ++EL +++ P + I + Q L T + P + ++ + Sbjct 959 VWELFNQ--ATKLPHEELTSEQVIQRSQAGTLEWT----------VAEATPDSLKEILLS 1006 Query 1151 CWETEASFRPTFENL 1165 CW RP+F L Sbjct 1007 CWLANPKERPSFSQL 1021 Score = 53.1 bits (126), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 61/260 (23%), Positives = 103/260 (40%), Gaps = 41/260 (16%) Query 636 ELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 E V++K L+ + A F L+ +SH + + G+C + MV EY + G Sbjct 782 EQLVLVKALNKVKDEQACQEFRRQLDLLRGISHKGVVRLFGLCREKDPHYMVLEYTDWGD 841 Query 695 LDVWLRRERGHVPMAWK------------MVVAQQLASALSYLENKNLVHGNVCGRNILL 742 L +L G V A + VA Q+A + + H ++ RN ++ Sbjct 842 LKQFLLATAGKVNTATATSSPPALTTSQVLAVAYQIARGMDAIYRSRCTHRDLATRNCVI 901 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDK 797 + + +K+S P + SRE R + WLAPEC+ + +T D Sbjct 902 S-------SEFVVKVSYPALCKDKYSREYHKHRNTLLPVRWLAPECIQ--EDEYTTKSDI 952 Query 798 WGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQH------RLPEPSCPQLATLTSQC 848 + +G + E+ F+ L P E+ E QR + E + L + C Sbjct 953 FAYGVLVWEL-FNQATKL----PHEELTSEQVIQRSQAGTLEWTVAEATPDSLKEILLSC 1007 Query 849 LTYEPTQRPSFRTILRDLTR 868 P +RPSF + L++ Sbjct 1008 WLANPKERPSFSQLGSALSK 1027 >sp|F4JZW1|PBL13_ARATH Serine/threonine-protein kinase PBL13 OS=Arabidopsis thaliana OX=3702 GN=PBL13 PE=1 SV=1 Length=494 Score = 89.4 bits (220), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 78/203 (38%), Positives = 102/203 (50%), Gaps = 15/203 (7%) Query 903 LGEGHFGKVSL-YCYDPTNDG-TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LGEG FG V + D G + VAVK L D HR + E+ L L H +++ Sbjct 82 LGEGGFGPVHKGFIDDKLRPGLKAQPVAVKLLDLDGLQGHRE-FMTEVMCLGKLKHPNLV 140 Query 961 KYKG-CCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGL--AQLLLFAQQICEGMAYLHA 1016 K G CCE E LV E++P GSL L R S+ L L A + +G+ +LH Sbjct 141 KLIGYCCE---EAHRLLVYEFMPRGSLESQLFRRCSLPLPWTTRLNIAYEAAKGLQFLHE 197 Query 1017 QH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE-YYRVREDGDSPVFWYAPECL 1073 I+RD A N+LLD+D K+ DFGLAK P+G + + R G + APE + Sbjct 198 AEKPIIYRDFKASNILLDSDYTAKLSDFGLAKDGPQGDDTHVSTRVMGTQG--YAAPEYI 255 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 SDV+SFGV L ELLT Sbjct 256 MTGHLTAKSDVYSFGVVLLELLT 278 Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 73/290 (25%), Positives = 118/290 (41%), Gaps = 45/290 (16%) Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 G G +G +DD+ L PG + Q V +K+LD F + ++ H +L Sbjct 86 GFGPVHKGFIDDK--LRPGL-KAQP--VAVKLLDLDGLQGHREFMTEVMCLGKLKHPNLV 140 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN-- 727 + G C ++V E++ G L+ L R R +P+ W ++ +A + A L +L Sbjct 141 KLIGYCCEEAHRLLVYEFMPRGSLESQLFR-RCSLPLPWTTRLNIAYEAAKGLQFLHEAE 199 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVE-RI----PWLAP 781 K +++ + NILL A KLSD G+ G + V R+ + AP Sbjct 200 KPIIYRDFKASNILLDSDYTA-------KLSDFGLAKDGPQGDDTHVSTRVMGTQGYAAP 252 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ------------- 828 E + G L+ D + FG LLE+ G + S KE + Sbjct 253 EYIMTG--HLTAKSDVYSFGVVLLEL-LTGRKSVDIARSSRKETLVEWARPMLNDARKLG 309 Query 829 ------RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 + + E + ATL QCL Y P RP T++ L ++ + Sbjct 310 RIMDPRLEDQYSETGARKAATLAYQCLRYRPKTRPDISTVVSVLQDIKDY 359 >sp|G5EFU0|PK2_CAEEL Serine/threonine-protein kinase pak-2 OS=Caenorhabditis elegans OX=6239 GN=pak-2 PE=2 SV=1 Length=522 Score = 89.4 bits (220), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 60/199 (30%), Positives = 97/199 (49%), Gaps = 10/199 (5%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L + +GEG G V T ++VAVK + Q R E+ ILR H Sbjct 231 LTDYKQIGEGSTGVVEAAY----KISTKQIVAVKRMNLRKQ-QRRELLFNEVSILRQYQH 285 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016 +I+++ E L +VME++ GSL D + + Q+ ++Q+ + +LHA Sbjct 286 PNIVRFFSSHLVDDE--LWVVMEFMEGGSLTDIVTATRMTEPQIATISRQVLGALDFLHA 343 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + IHRD+ + ++LL D VK+ DFG + E E R R +P +W A E + Sbjct 344 RKVIHRDIKSDSILLKRDGTVKLTDFGFCGQLSE--EVPRRRSLVGTP-YWTAAEVIARE 400 Query 1077 KFYYASDVWSFGVTLYELL 1095 + +D+WSFG+ L E++ Sbjct 401 PYDTRADIWSFGIMLIEMV 419 Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 55/223 (25%), Positives = 93/223 (42%), Gaps = 30/223 (13%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 + S++ Q H ++ + E +V E++E G L + R P + Sbjct 273 LFNEVSILRQYQHPNIVRFFSSHLVDDELWVVMEFMEGGSLTDIVTATRMTEPQI--ATI 330 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 ++Q+ AL +L + ++H ++ +ILL R G +KL+D G G LS E Sbjct 331 SRQVLGALDFLHARKVIHRDIKSDSILLKRDGT-------VKLTDFGF-CGQLSEEVPRR 382 Query 775 R----IP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP--------S 821 R P W A E + T D W FG L+E+ +GE P + P Sbjct 383 RSLVGTPYWTAAEVI--AREPYDTRADIWSFGIMLIEMV-EGEPPFFNDQPFQAMKRIRD 439 Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 E E + R ++ +L+ L S C+ + +R + +LR Sbjct 440 EHEARFSRHAKV----SVELSELLSHCIVKDVNKRWPAKDLLR 478 >sp|Q9M2Z1|BAME2_ARATH Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM2 OS=Arabidopsis thaliana OX=3702 GN=BAM2 PE=1 SV=1 Length=1002 Score = 90.5 bits (223), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 82/272 (30%), Positives = 127/272 (47%), Gaps = 42/272 (15%) Query 924 GEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982 G++VAVK L G H G+ EI L + H HI++ G C + E +L LV EY+P Sbjct 712 GDLVAVKRLATMSHGSSHDHGFNAEIQTLGRIRHRHIVRLLGFCSNH-ETNL-LVYEYMP 769 Query 983 LGSLRDYL-----------PRHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARN 1028 GSL + L R+ I L + +G+ YLH + +HRD+ + N Sbjct 770 NGSLGEVLHGKKGGHLHWNTRYKIAL--------EAAKGLCYLHHDCSPLIVHRDVKSNN 821 Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 +LLD++ + DFGLAK + + + S + APE K SDV+SFG Sbjct 822 ILLDSNFEAHVADFGLAKFLQDSGTSECMSAIAGS-YGYIAPEYAYTLKVDEKSDVYSFG 880 Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQ--------GQMTVLRLTELLERGERLPRPDKC 1140 V L EL+T + P +F + + I Q + VL++ +L R +P + Sbjct 881 VVLLELIT----GKKPVGEFGDGVDIVQWVRSMTDSNKDCVLKVIDL--RLSSVPVHEV- 933 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 V+++ C E +A RPT ++ IL + Sbjct 934 -THVFYVALLCVEEQAVERPTMREVVQILTEI 964 Score = 43.9 bits (102), Expect = 0.011, Method: Compositional matrix adjust. Identities = 57/247 (23%), Positives = 104/247 (42%), Gaps = 45/247 (18%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKM 712 F + ++ H H+ + G C N++V EY+ +G L +V ++ GH+ + Sbjct 732 GFNAEIQTLGRIRHRHIVRLLGFCSNHETNLLVYEYMPNGSLGEVLHGKKGGHLHWNTRY 791 Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPG 761 +A + A L YL + +VH +V NILL A GLA+ F++ S Sbjct 792 KIALEAAKGLCYLHHDCSPLIVHRDVKSNNILLDSNFEAHVADFGLAK----FLQDSGTS 847 Query 762 VGLGALSREERVERIPWLAPECLPGGANSLST--AMDKWGFGATLLEICFDGEAP----- 814 + A++ ++APE A +L D + FG LLE+ G+ P Sbjct 848 ECMSAIAGS-----YGYIAPEY----AYTLKVDEKSDVYSFGVVLLEL-ITGKKPVGEFG 897 Query 815 --------LQSRSPSEKEHFYQ----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 ++S + S K+ + R +P + + C+ + +RP+ R + Sbjct 898 DGVDIVQWVRSMTDSNKDCVLKVIDLRLSSVPVHEVTHVFYVALLCVEEQAVERPTMREV 957 Query 863 LRDLTRL 869 ++ LT + Sbjct 958 VQILTEI 964 >sp|O14299|WIS4_SCHPO MAP kinase kinase kinase wis4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=wis4 PE=3 SV=1 Length=1401 Score = 90.9 bits (224), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 85/279 (30%), Positives = 128/279 (46%), Gaps = 40/279 (14%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD- 902 L+ Q L E R I R+ T L+ + VL D +VF R K+ Sbjct 979 LSIQLLQKETMLRIDELEIERNNTLLERLAIGHVL---------DDSVFRNRDFIKLASS 1029 Query 903 -------LGEGHFGKVSLY--CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---EIDI 950 +GHF + ++ Y N TG+++AVK +K RS Q E+ + Sbjct 1030 FSNITIRWQQGHFVRSGMFGDVYTGVNMETGDLLAVKEIKLQDSRTFRSTVDQIHNEMTV 1089 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL-LFAQQICE 1009 L L H +++ Y G E EK + + ME+ GSL D L I +L ++ Q+ E Sbjct 1090 LERLNHPNVVTYYGV-EVHREK-VYIFMEFCQGGSLADLLAHGRIEDENVLKVYVVQLLE 1147 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV--PEGHEYYRVREDGDSPVF- 1066 G+AY+H+QH +HRD+ N+LLD+ ++K DFG A V P E VR + P Sbjct 1148 GLAYIHSQHILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPE---VRYEDIQPELQ 1204 Query 1067 -------WYAPECLKEYKF--YYASDVWSFGVTLYELLT 1096 + APE + K + A D+WS G + E++T Sbjct 1205 HLAGTPMYMAPEIILGTKKGDFGAMDIWSLGCVILEMMT 1243 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 68/266 (26%), Positives = 109/266 (41%), Gaps = 41/266 (15%) Query 614 GDPEEG-KMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672 GD G M+ D L + Q+ R +D H+++ +++ +++H ++ Sbjct 1049 GDVYTGVNMETGDLLAVKEIKLQDSRTFRSTVDQIHNEM--------TVLERLNHPNVVT 1100 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVH 732 +GV V + + E+ + G L L R K+ V Q L L+Y+ +++++H Sbjct 1101 YYGVEVHREKVYIFMEFCQGGSLADLLAHGRIEDENVLKVYVVQ-LLEGLAYIHSQHILH 1159 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA---LSREERVERIP-----------W 778 ++ NILL G+ IK SD G L E R E I + Sbjct 1160 RDIKPANILLDHRGM-------IKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAGTPMY 1212 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838 +APE + G AMD W G +LE+ G P S +E Y + PS Sbjct 1213 MAPEIILGTKKGDFGAMDIWSLGCVILEM-MTGSTPW-SEMDNEWAIMYHVA-AMHTPSI 1269 Query 839 PQLATLTS-------QCLTYEPTQRP 857 PQ ++S QC +P QRP Sbjct 1270 PQNEKISSLARDFIEQCFERDPEQRP 1295 >sp|Q7ZZC8|NEK9_XENLA Serine/threonine-protein kinase Nek9 OS=Xenopus laevis OX=8355 GN=nek9 PE=2 SV=1 Length=944 Score = 90.5 bits (223), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 80/277 (29%), Positives = 128/277 (46%), Gaps = 30/277 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEH 958 IR LG G +G+ +LY T D + +V K + A + R EI IL L H++ Sbjct 37 IRVLGHGAYGEATLY--RRTEDDS--LVVWKEVGLARLSEKERRDALNEIVILSLLQHDN 92 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMAYLH 1015 II Y D +L + +EY G+L D + L Q +L + QI ++ +H Sbjct 93 IIAYYNHFLDS--NTLLIELEYCNGGNLFDKIVHQKAQLFQEETVLWYLFQIVSAVSCIH 150 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRD+ N+ L L+K+GD+GLAK + Y + E +++ +PE + Sbjct 151 KAGILHRDIKTLNIFLTKANLIKLGDYGLAKQLS---SEYSMAETCVGTLYYMSPEICQG 207 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL-IGIAQGQMTVLRLTELLERGERL 1134 K+ + SD+W+ G LYELLT + + T L L + I QG V + + Sbjct 208 VKYSFKSDIWAVGCVLYELLTLTRTFDA--TNPLNLCVKIVQGNWAVGLDNTVYTQ---- 261 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PIL 1169 E+ ++ C E + RPT + ++ PIL Sbjct 262 --------ELIEVVHACLEQDPEKRPTADEILERPIL 290 >sp|E9PTG8|STK10_RAT Serine/threonine-protein kinase 10 OS=Rattus norvegicus OX=10116 GN=Stk10 PE=1 SV=1 Length=967 Score = 90.5 bits (223), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 60/200 (30%), Positives = 104/200 (52%), Gaps = 17/200 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +LG+G FGKV Y N TG + A K ++ + + EI+IL T H +I+K Sbjct 41 ELGDGAFGKV----YKAKNKETGALAAAKVIETK-SEEELEDYIVEIEILATCDHPYIVK 95 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019 G G+ L +++E+ P G++ + GL Q+ + +Q+ E + +LH + Sbjct 96 LLGAYYYDGK--LWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRI 153 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP-----ECLK 1074 IHRDL A NVL+ + +++ DFG++ + + + R+ +W AP E +K Sbjct 154 IHRDLKAGNVLMTLEGDIRLADFGVS---AKNLKTLQKRDSFIGTPYWMAPEVVLCETMK 210 Query 1075 EYKFYYASDVWSFGVTLYEL 1094 + + Y +D+WS G+TL E+ Sbjct 211 DAPYDYKADIWSLGITLIEM 230 Score = 40.8 bits (94), Expect = 0.11, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 47/103 (46%), Gaps = 14/103 (14%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV---GLGALSR 769 VV +Q+ AL++L K ++H ++ N+L+ G I+L+D GV L L + Sbjct 136 VVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEG-------DIRLADFGVSAKNLKTLQK 188 Query 770 EERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808 + P W+APE C D W G TL+E+ Sbjct 189 RDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWSLGITLIEMA 231 >sp|Q9FN94|RLK0_ARATH Receptor-like protein kinase At5g59670 OS=Arabidopsis thaliana OX=3702 GN=At5g59670 PE=1 SV=1 Length=868 Score = 90.5 bits (223), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 93/327 (28%), Positives = 145/327 (44%), Gaps = 27/327 (8%) Query 856 RPSFRTILRDLTRLQPH-NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 R TI++ L RL P ++ DV N S + + R LG+G FG V Sbjct 523 RKKMSTIVKGL-RLPPRTSMVDVTFSNKKSKRFTYSEVVQVTKNFQRVLGKGGFGMV--- 578 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG-CCEDQGEKS 973 Y T G+ E VAVK L + Q +K E+D+L ++H +++ G CCE Sbjct 579 -YHGTVKGS-EQVAVKVL-SQSSTQGSKEFKAEVDLLLRVHHTNLVSLVGYCCEGD---Y 632 Query 974 LQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAA 1026 L LV E++P G L+ +L I + L A + G+ YLH +HRD+ Sbjct 633 LALVYEFLPNGDLKQHLSGKGGNSIINWSIRLRIALEAALGLEYLHIGCTPPMVHRDVKT 692 Query 1027 RNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 N+LLD + K+ DFGL+++ EG G + + PEC + SDV+ Sbjct 693 ANILLDENFKAKLADFGLSRSFQGEGESQESTTIAG--TLGYLDPECYHSGRLGEKSDVY 750 Query 1086 SFGVTLYELLTH--CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE 1143 SFG+ L E++T+ + S + + +G QM + E+++ R Sbjct 751 SFGIVLLEMITNQPVINQTSGDSHITQWVGF---QMNRGDILEIMDPNLRKDYNINSAWR 807 Query 1144 VYHLMKNCWETEASFRPTFENLIPILK 1170 L +C +S RP+ +I LK Sbjct 808 ALELAMSCAYPSSSKRPSMSQVIHELK 834 Score = 54.7 bits (130), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 70/265 (26%), Positives = 105/265 (40%), Gaps = 54/265 (20%) Query 563 IMRGARASPRT----LNLSQLSFHRVDQKEITQLSH-----LGQGTRTNVYEGRLRVEGS 613 I++G R PRT + S R E+ Q++ LG+G VY G ++ Sbjct 529 IVKGLRLPPRTSMVDVTFSNKKSKRFTYSEVVQVTKNFQRVLGKGGFGMVYHGTVK---- 584 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 G E +V +KVL S + F L+ +V HT+L + Sbjct 585 --------------------GSE-QVAVKVLSQSSTQGSKEFKAEVDLLLRVHHTNLVSL 623 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NK 728 G C G +V E++ +G L L + G+ + W ++ +A + A L YL Sbjct 624 VGYCCEGDYLALVYEFLPNGDLKQHLSGKGGNSIINWSIRLRIALEAALGLEYLHIGCTP 683 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPE 782 +VH +V NILL A KL+D G+ E E + +L PE Sbjct 684 PMVHRDVKTANILLDENFKA-------KLADFGLSRSFQGEGESQESTTIAGTLGYLDPE 736 Query 783 CLPGGANSLSTAMDKWGFGATLLEI 807 C G L D + FG LLE+ Sbjct 737 CYHSG--RLGEKSDVYSFGIVLLEM 759 >sp|O55098|STK10_MOUSE Serine/threonine-protein kinase 10 OS=Mus musculus OX=10090 GN=Stk10 PE=1 SV=2 Length=966 Score = 90.5 bits (223), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 60/200 (30%), Positives = 104/200 (52%), Gaps = 17/200 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +LG+G FGKV Y N TG + A K ++ + + EI+IL T H +I+K Sbjct 41 ELGDGAFGKV----YKAKNKETGALAAAKVIETK-SEEELEDYIVEIEILATCDHPYIVK 95 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019 G G+ L +++E+ P G++ + GL Q+ + +Q+ E + +LH + Sbjct 96 LLGAYYYDGK--LWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRI 153 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP-----ECLK 1074 IHRDL A NVL+ + +++ DFG++ + + + R+ +W AP E +K Sbjct 154 IHRDLKAGNVLMTLEGDIRLADFGVS---AKNLKTLQKRDSFIGTPYWMAPEVVLCETMK 210 Query 1075 EYKFYYASDVWSFGVTLYEL 1094 + + Y +D+WS G+TL E+ Sbjct 211 DAPYDYKADIWSLGITLIEM 230 Score = 40.8 bits (94), Expect = 0.094, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 47/103 (46%), Gaps = 14/103 (14%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV---GLGALSR 769 VV +Q+ AL++L K ++H ++ N+L+ G I+L+D GV L L + Sbjct 136 VVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEG-------DIRLADFGVSAKNLKTLQK 188 Query 770 EERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808 + P W+APE C D W G TL+E+ Sbjct 189 RDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWSLGITLIEMA 231 >sp|Q290N5|PTK7_DROPS Tyrosine-protein kinase-like otk OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=otk PE=3 SV=2 Length=1037 Score = 90.5 bits (223), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 65/255 (25%), Positives = 120/255 (47%), Gaps = 30/255 (12%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 ++V VKAL Q +++++D+LR + H+ +++ G C ++ +V+EY G Sbjct 785 QLVLVKALNKVKDEQACQEFRRQLDLLRGISHKGVVRLFGLCREKDPH--YMVLEYTDWG 842 Query 985 SLRDYLPRHS--------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030 L+ +L + + +Q+L A QI GM ++ HRDLA RN + Sbjct 843 DLKQFLLATAGKVNTATATSSPPALTTSQVLAVAYQIARGMDAIYRSRCTHRDLATRNCV 902 Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 + ++ +VK+ L K EY++ R + PV W APEC++E ++ SD++++GV Sbjct 903 ISSEFVVKVSYPALCKD-KYSREYHKHR-NTLLPVRWLAPECIQEDEYTTKSDIFAYGVL 960 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 ++EL +++ P + I + Q L T + P + ++ + Sbjct 961 VWELFNQ--ATKLPHEELTSEQVIQRSQAGTLEWT----------VAEATPDSLKEILLS 1008 Query 1151 CWETEASFRPTFENL 1165 CW RP+F L Sbjct 1009 CWLANPKERPSFSQL 1023 Score = 53.1 bits (126), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 61/260 (23%), Positives = 103/260 (40%), Gaps = 41/260 (16%) Query 636 ELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 E V++K L+ + A F L+ +SH + + G+C + MV EY + G Sbjct 784 EQLVLVKALNKVKDEQACQEFRRQLDLLRGISHKGVVRLFGLCREKDPHYMVLEYTDWGD 843 Query 695 LDVWLRRERGHVPMAWK------------MVVAQQLASALSYLENKNLVHGNVCGRNILL 742 L +L G V A + VA Q+A + + H ++ RN ++ Sbjct 844 LKQFLLATAGKVNTATATSSPPALTTSQVLAVAYQIARGMDAIYRSRCTHRDLATRNCVI 903 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDK 797 + + +K+S P + SRE R + WLAPEC+ + +T D Sbjct 904 S-------SEFVVKVSYPALCKDKYSREYHKHRNTLLPVRWLAPECIQ--EDEYTTKSDI 954 Query 798 WGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQH------RLPEPSCPQLATLTSQC 848 + +G + E+ F+ L P E+ E QR + E + L + C Sbjct 955 FAYGVLVWEL-FNQATKL----PHEELTSEQVIQRSQAGTLEWTVAEATPDSLKEILLSC 1009 Query 849 LTYEPTQRPSFRTILRDLTR 868 P +RPSF + L++ Sbjct 1010 WLANPKERPSFSQLGSALSK 1029 >sp|Q1RMT8|IRAK4_BOVIN Interleukin-1 receptor-associated kinase 4 OS=Bos taurus OX=9913 GN=IRAK4 PE=2 SV=1 Length=461 Score = 89.0 bits (219), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 89/306 (29%), Positives = 132/306 (43%), Gaps = 43/306 (14%) Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP------SFRTILRDLTRLQPHNLA 875 + E F LP+ + TL S+ Q+P +++ D Q + L Sbjct 90 QNEFFAPASLLLPDAVPKNVNTLPSKVTVVAVQQKPKPLCGKDRTSVISDENPEQNYVLP 149 Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRD----------------LGEGHFGKV-SLYCYDP 918 D + S T FH +++D +GEG FG V Y + Sbjct 150 DSSSPENTSLEFSDTRFHSFSFFELKDVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNR 209 Query 919 TNDGTGEMVAVKALKA--DCGPQH-RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 T VAVK L A D + + + QEI ++ HE++++ G D + L Sbjct 210 T-------VAVKKLAAMVDISTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDD--LC 260 Query 976 LVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031 LV Y+P GSL D L + AQ G++YLH H+IHRD+ + N+LL Sbjct 261 LVYVYMPNGSLLDRLSCLDGTPPLSWNMRCKIAQGAANGLSYLHENHHIHRDIKSANILL 320 Query 1032 DNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 D D KI DFGLA+A + R G + + APE L+ + SD++SFGV Sbjct 321 DEDFTAKISDFGLARASEKFAQTVMTSRIVGTTA--YMAPEALRG-EITPKSDIYSFGVV 377 Query 1091 LYELLT 1096 L E++T Sbjct 378 LLEIIT 383 Score = 63.5 bits (153), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 57/257 (22%), Positives = 107/257 (42%), Gaps = 37/257 (14%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 +R ++ + ++D S ++ F + +M++ H +L + G G + +V Y+ Sbjct 207 NNRTVAVKKLAAMVDISTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYM 266 Query 691 EHGPLDVWLRRERGHVPMAWKM--VVAQQLASALSYLENKNLVHGNVCGRNILL------ 742 +G L L G P++W M +AQ A+ LSYL + +H ++ NILL Sbjct 267 PNGSLLDRLSCLDGTPPLSWNMRCKIAQGAANGLSYLHENHHIHRDIKSANILLDEDFTA 326 Query 743 --ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800 + GLA + F + + V ++APE L G ++ D + F Sbjct 327 KISDFGLARASEKFAQ---------TVMTSRIVGTTAYMAPEALRG---EITPKSDIYSF 374 Query 801 GATLLEICFDGEAPLQSRSPS---------------EKEHFYQRQHRLPEPSCPQLATLT 845 G LLEI A + R P +++ ++ + + S + ++ Sbjct 375 GVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYVDRKMNDIDSTSIETMYSVA 434 Query 846 SQCLTYEPTQRPSFRTI 862 SQCL + +RP + + Sbjct 435 SQCLHEKKNKRPDIKKV 451 >sp|Q14AX6|CDK12_MOUSE Cyclin-dependent kinase 12 OS=Mus musculus OX=10090 GN=Cdk12 PE=1 SV=2 Length=1484 Score = 90.9 bits (224), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 67/215 (31%), Positives = 102/215 (47%), Gaps = 37/215 (17%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958 +GEG +G+V Y + TGE+VA+K ++ D + G+ +EI ILR L H+ Sbjct 729 IGEGTYGQV----YKAKDKDTGELVALKKVRLD---NEKEGFPITAIREIKILRQLVHQS 781 Query 959 IIKYKGCCEDQGEK--------SLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQI 1007 ++ K D+ + + LV EY+ +G L L S + F +Q+ Sbjct 782 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSED--HIKSFMKQL 839 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED----GDS 1063 EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ Y E Sbjct 840 MEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLAR-------LYNSEESRPYTNKV 892 Query 1064 PVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096 WY P L E ++ A DVWS G L EL T Sbjct 893 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFT 927 Score = 35.8 bits (81), Expect = 3.0, Method: Compositional matrix adjust. Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 16/129 (12%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILL 742 +V EY++H D+ E G V + + + +QL L Y KN +H ++ NILL Sbjct 807 LVFEYMDH---DLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILL 863 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKW 798 G IKL+D G+ S E R ++ W P L G + A+D W Sbjct 864 NNSGQ-------IKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVW 916 Query 799 GFGATLLEI 807 G L E+ Sbjct 917 SCGCILGEL 925 >sp|Q9T020|Y4391_ARATH Probable receptor-like protein kinase At4g39110 OS=Arabidopsis thaliana OX=3702 GN=At4g39110 PE=3 SV=1 Length=878 Score = 90.5 bits (223), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 75/205 (37%), Positives = 101/205 (49%), Gaps = 28/205 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHEHI 959 +G G FG V + D DGT VAVK PQ G ++ EI +L L H H+ Sbjct 532 IGVGGFGNVYIGTLD---DGT--KVAVKR----GNPQSEQGITEFQTEIQMLSKLRHRHL 582 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ-QICEGMA----YL 1014 + G C++ E + LV E++ G RD+L + LA L + +IC G A YL Sbjct 583 VSLIGYCDENSE--MILVYEFMSNGPFRDHL--YGKNLAPLTWKQRLEICIGSARGLHYL 638 Query 1015 H---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-AP 1070 H AQ IHRD+ + N+LLD + K+ DFGL+K V G + G F Y P Sbjct 639 HTGTAQGIIHRDVKSTNILLDEALVAKVADFGLSKDVAFGQNHVSTAVKGS---FGYLDP 695 Query 1071 ECLKEYKFYYASDVWSFGVTLYELL 1095 E + + SDV+SFGV L E L Sbjct 696 EYFRRQQLTDKSDVYSFGVVLLEAL 720 Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 69/297 (23%), Positives = 117/297 (39%), Gaps = 39/297 (13%) Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651 LS L + T+ + V G G+ G +DD +V +K +P Sbjct 516 LSELQEATKNFEASQIIGVGGFGNVYIGTLDDG------------TKVAVKRGNPQSEQG 563 Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711 F ++S++ H HL + G C E I+V E++ +GP L + P+ WK Sbjct 564 ITEFQTEIQMLSKLRHRHLVSLIGYCDENSEMILVYEFMSNGPFRDHLYG-KNLAPLTWK 622 Query 712 MVVAQQLASA--LSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + + SA L YL + ++H +V NILL L + F D G Sbjct 623 QRLEICIGSARGLHYLHTGTAQGIIHRDVKSTNILLDE-ALVAKVADFGLSKDVAFGQNH 681 Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE-IC----FDGEAPLQSRSPS 821 +S + +L PE L+ D + FG LLE +C + + P + + + Sbjct 682 VSTAVK-GSFGYLDPEYFR--RQQLTDKSDVYSFGVVLLEALCARPAINPQLPREQVNLA 738 Query 822 EKEHFYQRQ---HRLPEP---------SCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 E ++R+ ++ +P S + A +CL RP+ +L +L Sbjct 739 EWAMQWKRKGLLEKIIDPHLAGTINPESMKKFAEAAEKCLEDYGVDRPTMGDVLWNL 795 >sp|Q61097|KSR1_MOUSE Kinase suppressor of Ras 1 OS=Mus musculus OX=10090 GN=Ksr1 PE=1 SV=1 Length=873 Score = 90.1 bits (222), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 75/283 (27%), Positives = 132/283 (47%), Gaps = 38/283 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ-HRSGWKQEIDILRTLYHEHIIK 961 +G+G +G+V + GE VA++ L+ D Q H +K+E+ R HE+++ Sbjct 569 IGQGRWGRVHRGRWH------GE-VAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVL 621 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G C + L ++ + +L ++ P+ S+ + + AQ+I +GM YLHA+ Sbjct 622 FMGACMNPPH--LAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGI 679 Query 1020 IHRDLAARNVLLDNDRLV--KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY- 1076 +H+DL ++NV DN ++V G FG++ V E +++ D + + APE ++E Sbjct 680 VHKDLKSKNVFYDNGKVVITDFGLFGISGVVREERRENQLKLSHDW-LCYLAPEIVREMI 738 Query 1077 --------KFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 F A+DV++FG YEL P + IG +G VL L Sbjct 739 PGRDEDQLPFSKAADVYAFGTVWYELQARDWPFKHQPAEALIWQIGSGEGVRRVLASVSL 798 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + EV ++ CW + RP+F L+ +L+ Sbjct 799 GK-------------EVGEILSACWAFDLQERPSFSLLMDMLE 828 Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 41/188 (22%), Positives = 79/188 (42%), Gaps = 24/188 (13%) Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 E+ + L +D + D F + Q H ++ G C+ P ++T + + L Sbjct 585 EVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTL 644 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 ++R + + + +AQ++ + YL K +VH ++ +N+ + + Sbjct 645 HSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFY--------DNGKV 696 Query 756 KLSDPGV-GLGALSREERVER--------IPWLAPEC----LPGGANS---LSTAMDKWG 799 ++D G+ G+ + REER E + +LAPE +PG S A D + Sbjct 697 VITDFGLFGISGVVREERRENQLKLSHDWLCYLAPEIVREMIPGRDEDQLPFSKAADVYA 756 Query 800 FGATLLEI 807 FG E+ Sbjct 757 FGTVWYEL 764 >sp|Q15569|TESK1_HUMAN Dual specificity testis-specific protein kinase 1 OS=Homo sapiens OX=9606 GN=TESK1 PE=1 SV=2 Length=626 Score = 89.7 bits (221), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 80/295 (27%), Positives = 126/295 (43%), Gaps = 50/295 (17%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G F +V Y + +G+++ +K K P +R +E+ ++ L H +I+++ Sbjct 63 IGAGFFSEV----YKVRHRQSGQVMVLKMNKL---PSNRGNTLREVQLMNRLRHPNILRF 115 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G C QG+ L + EY+ G+L L + L A I G+ YLH++ H Sbjct 116 MGVCVHQGQ--LHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIARGLRYLHSKGVFH 173 Query 1022 RDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVFWYAPECLKEY 1076 RDL ++N L+ D +GDFGLA+ +P E R SP +W APE L+ Sbjct 174 RDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSP-YWMAPEVLRGE 232 Query 1077 KFYYASDVWSFGVTLYELLTH--CDSSQSPPTK--------FLELIGIAQGQMTVLRLTE 1126 + +DV++FG+ L EL+ D P T+ F L+G Sbjct 233 LYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVG------------- 279 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 D CP L +C E S R F + L+ + E+ AP Sbjct 280 -----------DDCPLPFLLLAIHCCNLEPSTRAPFTEITQHLEWILEQLPEPAP 323 Score = 46.6 bits (109), Expect = 0.002, Method: Compositional matrix adjust. Identities = 81/319 (25%), Positives = 121/319 (38%), Gaps = 73/319 (23%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 R L + S RVD + +G G + VY+ R R SG KM+ +P Sbjct 42 RALRSAVSSLARVDDFHCAE--KIGAGFFSEVYKVRHR--QSGQVMVLKMNK----LPS- 92 Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +RG LR V LM+++ H ++ GVCV + +TEY+ Sbjct 93 NRGNTLREV-------------------QLMNRLRHPNILRFMGVCVHQGQLHALTEYMN 133 Query 692 HGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLAR----- 744 G L+ L P++W ++ +A +A L YL +K + H ++ +N L+ R Sbjct 134 GGTLEQLLSSPE---PLSWPVRLHLALDIARGLRYLHSKGVFHRDLTSKNCLVRREDRGF 190 Query 745 ------LGLAEGTSPFIKLSDPGVGLGALSREERVERIP-WLAPECLPGGANSLSTAMDK 797 GLAE P GA V P W+APE L G D Sbjct 191 TAVVGDFGLAEKI--------PVYREGARKEPLAVVGSPYWMAPEVLRG--ELYDEKADV 240 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---------HRLPEPSCP-QLATLTSQ 847 + FG L E L +R P++ ++ + + L CP L Sbjct 241 FAFGIVLCE--------LIARVPADPDYLPRTEDFGLDVPAFRTLVGDDCPLPFLLLAIH 292 Query 848 CLTYEPTQRPSFRTILRDL 866 C EP+ R F I + L Sbjct 293 CCNLEPSTRAPFTEITQHL 311 >sp|Q9M8S2|LIPG2_ARATH Receptor-like kinase LIP2 OS=Arabidopsis thaliana OX=3702 GN=LIP2 PE=1 SV=1 Length=558 Score = 89.4 bits (220), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 73/203 (36%), Positives = 104/203 (51%), Gaps = 16/203 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG+V Y T TG++VAVK L G ++ E+ L L H +++K Sbjct 70 LGEGGFGRV----YKGTLKSTGQVVAVKQLDK-HGLHGNKEFQAEVLSLGQLDHPNLVKL 124 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHS---IGLAQLLLFAQQICEGMAYLHAQ 1017 G C D G++ L LV +Y+ GSL+D+L P+ + + A +G+ YLH + Sbjct 125 IGYCAD-GDQRL-LVYDYISGGSLQDHLHEPKADSDPMDWTTRMQIAYAAAQGLDYLHDK 182 Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECL 1073 I+RDL A N+LLD+D K+ DFGL K P G + + + APE Sbjct 183 ANPPVIYRDLKASNILLDDDFSPKLSDFGLHKLGPGTGDKMMALSSRVMGTYGYSAPEYT 242 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 + SDV+SFGV L EL+T Sbjct 243 RGGNLTLKSDVYSFGVVLLELIT 265 Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 61/238 (26%), Positives = 103/238 (43%), Gaps = 37/238 (16%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV-PMAW--KMVVAQQL 718 + Q+ H +L + G C G + ++V +Y+ G L L + PM W +M +A Sbjct 113 LGQLDHPNLVKLIGYCADGDQRLLVYDYISGGSLQDHLHEPKADSDPMDWTTRMQIAYAA 172 Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD-------PGVGLGALSREE 771 A L YL +K + V R++ + + L + SP KLSD PG G ++ Sbjct 173 AQGLDYLHDK--ANPPVIYRDLKASNILLDDDFSP--KLSDFGLHKLGPGTGDKMMALSS 228 Query 772 RVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF---- 826 RV + APE GG +L+ D + FG LLE+ G L + P+++++ Sbjct 229 RVMGTYGYSAPEYTRGG--NLTLKSDVYSFGVVLLELIT-GRRALDTTRPNDEQNLVSWA 285 Query 827 ---YQRQHRLPEPSCP------------QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 ++ R P+ + P Q + S C+ E + RP ++ L+ L Sbjct 286 QPIFRDPKRYPDMADPVLENKFSERGLNQAVAIASMCVQEEASARPLISDVMVALSFL 343 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens OX=9606 GN=PAK4 PE=1 SV=1 Length=591 Score = 89.4 bits (220), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 69/237 (29%), Positives = 111/237 (47%), Gaps = 21/237 (9%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 L V+P P S YL +GEG G V + T +G++VAVK K D Sbjct 310 LVVDPGDPRS--------YLDNFIKIGEGSTGIVCIA----TVRSSGKLVAVK--KMDLR 355 Query 938 PQHRSGWK-QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996 Q R E+ I+R HE++++ E L +VME++ G+L D + + Sbjct 356 KQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDE--LWVVMEFLEGGALTDIVTHTRMN 413 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 Q+ + + ++ LHAQ IHRD+ + ++LL +D VK+ DFG V E R Sbjct 414 EEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQV--SKEVPR 471 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELI 1112 + +P +W APE + + D+WS G+ + E++ PP K +++I Sbjct 472 RKSLVGTP-YWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMI 527 >sp|Q9WTQ0|KPCT_RAT Protein kinase C theta type OS=Rattus norvegicus OX=10116 GN=Prkcq PE=1 SV=2 Length=707 Score = 89.7 bits (221), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 68/209 (33%), Positives = 102/209 (49%), Gaps = 23/209 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI-LRTLYHEHIIK 961 LG+G FGKV L + T + A+KALK D ++ + +L EH Sbjct 386 LGKGSFGKVFLAEFKRTK----QFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFL 441 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 C Q +++L VMEY+ G L ++ H L++ +A ++ G+ +LH++ + Sbjct 442 THMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEVILGLQFLHSKGIV 501 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WYAPECLKE 1075 +RDL N+LLD D +KI DFG+ K G D + F + APE L Sbjct 502 YRDLKLDNILLDRDGHIKIADFGMCKENMLG--------DAKTNTFCGTPDYIAPEILLG 553 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 K+ ++ D WSFGV LYE+L QSP Sbjct 554 QKYNHSVDWWSFGVLLYEMLI----GQSP 578 >sp|A8WZ92|SPE8_CAEBR Spermatocyte protein spe-8 OS=Caenorhabditis briggsae OX=6238 GN=spe-8 PE=2 SV=2 Length=479 Score = 89.0 bits (219), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 52/142 (37%), Positives = 82/142 (58%), Gaps = 10/142 (7%) Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLH 1015 ++IK+ G C ++ + +VME+ SL D L + +L+ G+ YLH Sbjct 244 NVIKFYGVC--TMKEPIMIVMEFCDGSSLEDVLLSKESKVSSEDKILYLFHAACGIDYLH 301 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLA-KAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 +H IHRD+AARN LL++ +++KI DFGL+ K V + R+ G PV + APE LK Sbjct 302 GKHVIHRDIAARNCLLNSKKVLKISDFGLSVKGVA-----IKERKGGCLPVKYMAPETLK 356 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + + ASD++S+G +YE+ T Sbjct 357 KGFYSTASDIYSYGALVYEVYT 378 Score = 62.4 bits (150), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 50/198 (25%), Positives = 91/198 (46%), Gaps = 17/198 (9%) Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHG 733 +GVC ++V E+ + L+ L + V K++ A + YL K+++H Sbjct 249 YGVCTMKEPIMIVMEFCDGSSLEDVLLSKESKVSSEDKILYLFHAACGIDYLHGKHVIHR 308 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER---IPWLAPECLPGGANS 790 ++ RN LL + +K+SD G+ + ++ +ER + ++APE L G Sbjct 309 DIAARNCLL-------NSKKVLKISDFGLSVKGVAIKERKGGCLPVKYMAPETLKKGF-- 359 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQS---RSPSEKEHFYQRQHRLP-EPSCPQLA-TLT 845 STA D + +GA + E+ DG+ P +S R ++ + L + CP+ + Sbjct 360 YSTASDIYSYGALVYEVYTDGKTPFESCGLRGNELRKAIIGKSVILTIDVECPEFVKAIF 419 Query 846 SQCLTYEPTQRPSFRTIL 863 Q Y+ QR S + I+ Sbjct 420 EQSRLYDTEQRISSKRII 437 >sp|Q3MJK5|CDK12_RAT Cyclin-dependent kinase 12 OS=Rattus norvegicus OX=10116 GN=Cdk12 PE=1 SV=1 Length=1484 Score = 90.5 bits (223), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 67/215 (31%), Positives = 102/215 (47%), Gaps = 37/215 (17%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958 +GEG +G+V Y + TGE+VA+K ++ D + G+ +EI ILR L H+ Sbjct 729 IGEGTYGQV----YKAKDKDTGELVALKKVRLD---NEKEGFPITAIREIKILRQLVHQS 781 Query 959 IIKYKGCCEDQGEK--------SLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQI 1007 ++ K D+ + + LV EY+ +G L L S + F +Q+ Sbjct 782 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSED--HIKSFMKQL 839 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED----GDS 1063 EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ Y E Sbjct 840 MEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLAR-------LYNSEESRPYTNKV 892 Query 1064 PVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096 WY P L E ++ A DVWS G L EL T Sbjct 893 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFT 927 Score = 36.2 bits (82), Expect = 2.6, Method: Compositional matrix adjust. Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 16/129 (12%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILL 742 +V EY++H D+ E G V + + + +QL L Y KN +H ++ NILL Sbjct 807 LVFEYMDH---DLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILL 863 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKW 798 G IKL+D G+ S E R ++ W P L G + A+D W Sbjct 864 NNSGQ-------IKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVW 916 Query 799 GFGATLLEI 807 G L E+ Sbjct 917 SCGCILGEL 925 >sp|Q552C1|Y9957_DICDI Probable serine/threonine-protein kinase DDB_G0276181 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0276181 PE=3 SV=1 Length=1555 Score = 90.5 bits (223), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 76/285 (27%), Positives = 125/285 (44%), Gaps = 47/285 (16%) Query 913 LYCYDPTND--------GTGE--MVAVKALK--ADCGPQHRSGWKQEIDILRTLYHEHII 960 L +P+ND G+G +VAVK L AD P+ + E+ +L H +++ Sbjct 1034 LIARNPSNDIINKDAIIGSGPQIIVAVKKLHPLADPSPEMIQDFYNEVRVLSMFNHPNVV 1093 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 KY G C S+ VMEYVP G+L D L P I +L A I +G+ YLH+ Sbjct 1094 KYVGGCTKIANWSI--VMEYVPGGNLMDVLANPVLVIPYKLVLRMALDIAKGLHYLHSLG 1151 Query 1019 YIHRDLAARNVLLDNDRL-----VKIGDFG--LAKAVPEGHEYYRVREDGDS-------- 1063 +H D+ + N+L+ + +K+ DF + ++ + R GD+ Sbjct 1152 ILHLDMKSPNLLVSSLSTSAKVNIKVADFNTCINRSRITAGFFNRHTGSGDNNKVEKDSK 1211 Query 1064 --PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 W APE ++ + DV+SF + ++E++T + P + + Q+ Sbjct 1212 KGTTLWMAPEVIRGAMYSEKCDVYSFAIIMWEMVT-----RKLPYSHIAFNCEVEDQVL- 1265 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 +G R P P C LM+ CW+ + RP F+ +I Sbjct 1266 --------KGLRPPIPMHCNKNYTDLMEQCWDDDPENRPYFDTII 1302 Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 64/265 (24%), Positives = 107/265 (40%), Gaps = 30/265 (11%) Query 634 GQELRVVLKVL----DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G ++ V +K L DPS I FY ++S +H ++ G C + +V EY Sbjct 1053 GPQIIVAVKKLHPLADPSPEMIQ-DFYNEVRVLSMFNHPNVVKYVGGCTKIANWSIVMEY 1111 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 V G L L +P + +A +A L YL + ++H ++ N+L++ L + Sbjct 1112 VPGGNLMDVLANPVLVIPYKLVLRMALDIAKGLHYLHSLGILHLDMKSPNLLVSSLSTSA 1171 Query 750 GTSPFIKLSDPG-------VGLGALSR------EERVER------IPWLAPECLPGGANS 790 + IK++D + G +R +VE+ W+APE + G Sbjct 1172 KVN--IKVADFNTCINRSRITAGFFNRHTGSGDNNKVEKDSKKGTTLWMAPEVIRGAM-- 1227 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQLAT-LTSQC 848 S D + F + E+ E E + R P P C + T L QC Sbjct 1228 YSEKCDVYSFAIIMWEMVTRKLPYSHIAFNCEVEDQVLKGLRPPIPMHCNKNYTDLMEQC 1287 Query 849 LTYEPTQRPSFRTILRDLTRLQPHN 873 +P RP F TI+ ++++ N Sbjct 1288 WDDDPENRPYFDTIIHSISKMIESN 1312 >sp|Q6CWQ4|IPL1_KLULA Spindle assembly checkpoint kinase OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=IPL1 PE=3 SV=1 Length=361 Score = 87.4 bits (215), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 57/197 (29%), Positives = 104/197 (53%), Gaps = 13/197 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960 LG+G FGKV YC + TG + A+KA++ Q+ + +++E++I + H+++ Sbjct 106 LGKGKFGKV--YCV--KHRETGLICALKAMEKKEIVQYTIQKQFRREVEIQGSFKHKNLT 161 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019 + G D EK + L+MEYV G L +L + + F Q+ + Y+H+++ Sbjct 162 QLYGFFYD--EKRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDYMHSKNI 219 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRD+ N+L+ + +K+ DFG + +G + R+ + + +PE +K ++ Sbjct 220 LHRDIKPENILIGFNNTIKLTDFGWSVYNEDGQK----RKTLCGTIDYLSPELIKSREYN 275 Query 1080 YASDVWSFGVTLYELLT 1096 DVW+ GV YELL Sbjct 276 NKVDVWALGVLTYELLV 292 Score = 59.7 bits (143), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 53/216 (25%), Positives = 91/216 (42%), Gaps = 21/216 (10%) Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 + I F + H +L ++G ++ EYV +G L +L+ G + Sbjct 138 QYTIQKQFRREVEIQGSFKHKNLTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNN-GPLN 196 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--- 764 Q+A+AL Y+ +KN++H ++ NIL+ G + IKL+D G + Sbjct 197 ETLASYFVYQMANALDYMHSKNILHRDIKPENILI-------GFNNTIKLTDFGWSVYNE 249 Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 R+ I +L+PE + + + +D W G E+ G P + + KE Sbjct 250 DGQKRKTLCGTIDYLSPELIK--SREYNNKVDVWALGVLTYELLV-GSPPFEEDT---KE 303 Query 825 HFYQRQHR----LPEPSCPQLATLTSQCLTYEPTQR 856 Y+R R P PQ L + L +EP++R Sbjct 304 MTYRRILRCDLKFPLNVSPQARDLIVRLLQFEPSKR 339 >sp|P10398|ARAF_HUMAN Serine/threonine-protein kinase A-Raf OS=Homo sapiens OX=9606 GN=ARAF PE=1 SV=2 Length=606 Score = 89.4 bits (220), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 75/261 (29%), Positives = 118/261 (45%), Gaps = 42/261 (16%) Query 927 VAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 VAVK LK + + +K E+ +LR H +I+ + G G ++ ++ S Sbjct 333 VAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG---FAIITQWCEGSS 389 Query 986 LRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 L +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L VKIGDFG Sbjct 390 LYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFG 449 Query 1044 LAKAVPEGHEYYRVREDGDSP-------VFWYAPECLKEYK---FYYASDVWSFGVTLYE 1093 LA + R G P V W A E ++ + + SDV+++GV LYE Sbjct 450 LATV--------KTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYE 501 Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK----CPCEVYHLMK 1149 L+T S P IG ++ ++ RG P K CP + L+ Sbjct 502 LMT-----GSLPYSH---IGCRD------QIIFMVGRGYLSPDLSKISSNCPKAMRRLLS 547 Query 1150 NCWETEASFRPTFENLIPILK 1170 +C + + RP F ++ ++ Sbjct 548 DCLKFQREERPLFPQILATIE 568 Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 68/255 (27%), Positives = 106/255 (42%), Gaps = 24/255 (9%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 GR G VLKV P+ A AF ++ + H ++ G R P ++T++ Sbjct 327 GRWHGDVAVKVLKVSQPTAEQ-AQAFKNEMQVLRKTRHVNILLFMGFMTR-PGFAIITQW 384 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 E L L M + VA+Q A + YL KN++H ++ NI L E Sbjct 385 CEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIF-----LHE 439 Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP-GGANSLSTAMDKWGFGA 802 G + +K+ D G+ GA E+ + W+A E + N S D + +G Sbjct 440 GLT--VKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGV 497 Query 803 TLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQ 855 L E+ G P ++ F R + P+ S CP+ + L S CL ++ + Sbjct 498 VLYEL-MTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREE 556 Query 856 RPSFRTILRDLTRLQ 870 RP F IL + LQ Sbjct 557 RPLFPQILATIELLQ 571 >sp|O22833|LRK54_ARATH L-type lectin-domain containing receptor kinase V.4 OS=Arabidopsis thaliana OX=3702 GN=LECRK54 PE=2 SV=1 Length=658 Score = 89.7 bits (221), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 64/200 (32%), Positives = 103/200 (52%), Gaps = 18/200 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+V + T G+ +AVK + D Q + EI + L H+++++ Sbjct 340 LGKGGFGQV----FKGTLPGSDAEIAVKRISHDS-KQGMQEFLAEISTIGRLRHQNLVRL 394 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH--- 1015 +G C + E L LV +++P GSL YL + + Q + I + YLH Sbjct 395 QGYCRYKEE--LYLVYDFMPNGSLDKYLYHRANQEQLTWNQRFKIIKDIASALCYLHHEW 452 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074 Q IHRD+ NVL+D+ ++GDFGLAK +G++ R G FWY APE ++ Sbjct 453 VQVVIHRDIKPANVLIDHQMNARLGDFGLAKLYDQGYDPQTSRVAG---TFWYIAPELIR 509 Query 1075 EYKFYYASDVWSFGVTLYEL 1094 + +DV++FG+ + E+ Sbjct 510 SGRATTGTDVYAFGLFMLEV 529 Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 45/197 (23%), Positives = 87/197 (44%), Gaps = 14/197 (7%) Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 G + + +K + F S + ++ H +L + G C E +V +++ +G Sbjct 355 GSDAEIAVKRISHDSKQGMQEFLAEISTIGRLRHQNLVRLQGYCRYKEELYLVYDFMPNG 414 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLA-RLGL 747 LD +L + W + + + +ASAL YL + + ++H ++ N+L+ ++ Sbjct 415 SLDKYLYHRANQEQLTWNQRFKIIKDIASALCYLHHEWVQVVIHRDIKPANVLIDHQMNA 474 Query 748 AEGTSPFIKLSDPGVGLGALSREERVERIPW-LAPECLPGGANSLSTAMDKWGFGATLLE 806 G KL D G + RV W +APE + G +T D + FG +LE Sbjct 475 RLGDFGLAKLYDQGYD----PQTSRVAGTFWYIAPELIRSG--RATTGTDVYAFGLFMLE 528 Query 807 ICFDGEAPLQSRSPSEK 823 + G ++ R+ S++ Sbjct 529 VSC-GRRLIERRTASDE 544 >sp|Q9R012|PLK2_RAT Serine/threonine-protein kinase PLK2 OS=Rattus norvegicus OX=10116 GN=Plk2 PE=1 SV=1 Length=682 Score = 89.7 bits (221), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 76/283 (27%), Positives = 130/283 (46%), Gaps = 32/283 (11%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWK 945 DPT KRY + + LG+G F K CY+ T+ ++ A K + P R Sbjct 72 DPTT-GKRYCRG-KVLGKGGFAK----CYEMTDLTNNKVYAAKIIPHSRVAKPHQREKID 125 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFA 1004 +EI++ R L+H+H++++ ED+ +++ +++EY S+ L R + ++ + Sbjct 126 KEIELHRILHHKHVVQFYHYFEDK--ENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 183 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDS 1063 +QI G+ YLH Q +HRDL N ++ +K+GDFGLA + P H R R + Sbjct 184 RQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEH---RRRTICGT 240 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 P + +PE L + SD+W+ G +Y + L+G + T L+ Sbjct 241 PNYL-SPEVLNKQGHGCESDIWALGCVMYTM----------------LLGRPPFETTNLK 283 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 T R R P HL+ + RP+ +++I Sbjct 284 ETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDII 326 >sp|B5X564|CDC2C_ARATH Cyclin-dependent kinase C-2 C OS=Arabidopsis thaliana OX=3702 GN=CDC2C PE=1 SV=1 Length=644 Score = 89.4 bits (220), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 67/205 (33%), Positives = 100/205 (49%), Gaps = 15/205 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLY 955 +K+ +G+G + V + TG+MVA+K +K D P+ +EI ILR L Sbjct 105 FQKLEKIGQGTYSSV----FRAREVETGKMVALKKVKFDNLQPESIRFMAREILILRKLN 160 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013 H +I+K +G + S+ LV EY+ L L P Q+ + +Q+ G+ + Sbjct 161 HPNIMKLEGIVTSRASSSIYLVFEYMEHDLAGLSSN-PDIRFTEPQIKCYMKQLLWGLEH 219 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWY-APE 1071 H + IHRD+ A N+L++N ++K+GDFGLA V P R WY APE Sbjct 220 CHMRGVIHRDIKASNILVNNKGVLKLGDFGLANVVTPSNKNQLTSR----VVTLWYRAPE 275 Query 1072 CLKEYKFYYAS-DVWSFGVTLYELL 1095 L Y S D+WS G E+L Sbjct 276 LLMGSTSYGVSVDLWSVGCVFAEIL 300 >sp|Q9FFW5|PERK8_ARATH Proline-rich receptor-like protein kinase PERK8 OS=Arabidopsis thaliana OX=3702 GN=PERK8 PE=1 SV=1 Length=681 Score = 89.4 bits (220), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 91/292 (31%), Positives = 131/292 (45%), Gaps = 37/292 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG C G VAVK LK G Q +K E++I+ ++H H++ Sbjct 345 LGEGGFG-----CVYKGVLSDGREVAVKQLKI-GGSQGEREFKAEVEIISRVHHRHLVTL 398 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017 G C E+ LV +YVP +L +L H+ G + + A G+AYLH Sbjct 399 VGYC--ISEQHRLLVYDYVPNNTLHYHL--HAPGRPVMTWETRVRVAAGAARGIAYLHED 454 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRD+ + N+LLDN + DFGLAK E V + APE Sbjct 455 CHPRIIHRDIKSSNILLDNSFEALVADFGLAKIAQELDLNTHVSTRVMGTFGYMAPEYAT 514 Query 1075 EYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQ---GQ-MTVLRLTEL 1127 K +DV+S+GV L EL+T D+SQ P L+ A+ GQ + EL Sbjct 515 SGKLSEKADVYSYGVILLELITGRKPVDTSQ--PLGDESLVEWARPLLGQAIENEEFDEL 572 Query 1128 LERGERLPRPDK--CPCEVYHLMK---NCWETEASFRPTFENLIPILKTVHE 1174 ++ PR K P E++ +++ C A+ RP ++ L T+ E Sbjct 573 VD-----PRLGKNFIPGEMFRMVEAAAACVRHSAAKRPKMSQVVRALDTLEE 619 Score = 43.1 bits (100), Expect = 0.019, Method: Compositional matrix adjust. Identities = 58/251 (23%), Positives = 97/251 (39%), Gaps = 47/251 (19%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F ++S+V H HL + G C+ ++V +YV + L L G M W ++ Sbjct 380 FKAEVEIISRVHHRHLVTLVGYCISEQHRLLVYDYVPNNTLHYHLHAP-GRPVMTWETRV 438 Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPG 761 VA A ++YL ++H ++ NILL A GLA K++ Sbjct 439 RVAAGAARGIAYLHEDCHPRIIHRDIKSSNILLDNSFEALVADFGLA-------KIAQE- 490 Query 762 VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP- 820 + L + ++APE G LS D + +G LLE+ G P+ + P Sbjct 491 LDLNTHVSTRVMGTFGYMAPEYATSG--KLSEKADVYSYGVILLEL-ITGRKPVDTSQPL 547 Query 821 ----------------SEKEHFYQ-RQHRLPEPSCP----QLATLTSQCLTYEPTQRPSF 859 E E F + RL + P ++ + C+ + +RP Sbjct 548 GDESLVEWARPLLGQAIENEEFDELVDPRLGKNFIPGEMFRMVEAAAACVRHSAAKRPKM 607 Query 860 RTILRDLTRLQ 870 ++R L L+ Sbjct 608 SQVVRALDTLE 618 >sp|P53351|PLK2_MOUSE Serine/threonine-protein kinase PLK2 OS=Mus musculus OX=10090 GN=Plk2 PE=1 SV=1 Length=682 Score = 89.4 bits (220), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 76/283 (27%), Positives = 130/283 (46%), Gaps = 32/283 (11%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWK 945 DPT KRY + + LG+G F K CY+ T+ ++ A K + P R Sbjct 72 DPTT-GKRYCRG-KVLGKGGFAK----CYEMTDLTNNKVYAAKIIPHSRVAKPHQREKID 125 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFA 1004 +EI++ R L+H+H++++ ED+ +++ +++EY S+ L R + ++ + Sbjct 126 KEIELHRLLHHKHVVQFYHYFEDK--ENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 183 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDS 1063 +QI G+ YLH Q +HRDL N ++ +K+GDFGLA + P H R R + Sbjct 184 RQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEH---RRRTICGT 240 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 P + +PE L + SD+W+ G +Y + L+G + T L+ Sbjct 241 PNYL-SPEVLNKQGHGCESDIWALGCVMYTM----------------LLGRPPFETTNLK 283 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 T R R P HL+ + RP+ +++I Sbjct 284 ETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDII 326 >sp|Q2TA25|PLK1_BOVIN Serine/threonine-protein kinase PLK1 OS=Bos taurus OX=9913 GN=PLK1 PE=2 SV=2 Length=602 Score = 89.4 bits (220), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 76/267 (28%), Positives = 117/267 (44%), Gaps = 28/267 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960 LG+G F K C++ ++ T E+ A K + P + EI I R+L H+H++ Sbjct 57 LGKGGFAK----CFEISDADTKEVFAGKIVPKSLLLKPHQKEKMSMEISIHRSLAHQHVV 112 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G ED + +V+E SL + + R ++ + + +QI G YLH Sbjct 113 GFHGFFEDND--FVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHGNRV 170 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRDL N+ L+ D VKIGDFGLA V E R + +P + APE L + Sbjct 171 IHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGE--RKKTLCGTPN-YIAPEVLSKKGHS 227 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 + DVWS G +Y L L+G + + L+ T L + P Sbjct 228 FEVDVWSIGCIMYTL----------------LVGKPPFETSCLKETYLRIKNNEYSIPKH 271 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLI 1166 L+K + + + RPT L+ Sbjct 272 INPVASSLIKKMLQPDPTARPTIHELL 298 Score = 40.8 bits (94), Expect = 0.079, Method: Compositional matrix adjust. Identities = 45/211 (21%), Positives = 83/211 (39%), Gaps = 16/211 (8%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+ ++H H+ HG +V E L + L + R + +Q+ Sbjct 101 SIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSL-LELHKRRKALTEPEARYYLRQIV 159 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776 YL ++H R++ L L L E +K+ D G+ ER + + Sbjct 160 LGCQYLHGNRVIH-----RDLKLGNLFLNEDLE--VKIGDFGLATKVEYDGERKKTLCGT 212 Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLP 834 ++APE L +S +D W G + + G+ P ++ E ++ +P Sbjct 213 PNYIAPEVLSKKGHSFE--VDVWSIGCIMYTLLV-GKPPFETSCLKETYLRIKNNEYSIP 269 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + P ++L + L +PT RP+ +L D Sbjct 270 KHINPVASSLIKKMLQPDPTARPTIHELLND 300 >sp|Q9HGY5|PHO85_CANAX Negative regulator of the PHO system OS=Candida albicans OX=5476 GN=PHO85 PE=3 SV=1 Length=326 Score = 86.3 bits (212), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 62/206 (30%), Positives = 99/206 (48%), Gaps = 17/206 (8%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +++ LGEG + V Y N TG +VA+K + D S +EI +++ L H Sbjct 8 FQQLEKLGEGTYATV----YKGRNRATGALVALKEISLDSEEGTPSTAIREISLMKELDH 63 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----SIGLAQLLLFAQQICEGMA 1012 E+I+ E L LV EY+ L+ Y+ H ++ L + F Q+ +G+ Sbjct 64 ENIVTLYDVI--HTENKLTLVFEYMD-KDLKKYMEVHGQQSALDLKVVKSFMFQLLKGIM 120 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APE 1071 + H +HRDL +N+L++N +K+GDFGLA+A + + WY AP+ Sbjct 121 FCHDNRVLHRDLKPQNLLINNKGELKLGDFGLARAFGIPFNTF----SNEVVTLWYRAPD 176 Query 1072 CLKEYKFYYAS-DVWSFGVTLYELLT 1096 L + Y S D+WS G E+ T Sbjct 177 VLLGSRAYTTSIDIWSAGCIFAEMCT 202 Score = 41.2 bits (95), Expect = 0.046, Method: Compositional matrix adjust. Identities = 51/227 (22%), Positives = 96/227 (42%), Gaps = 38/227 (17%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + QL LG+GT VY+GR R G+ LV ++ LD Sbjct 7 QFQQLEKLGEGTYATVYKGRNRATGA-------------LVALKEIS---------LDSE 44 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 + A E SLM ++ H ++ ++ V + +V EY++ L ++ Sbjct 45 EGTPSTAIREI-SLMKELDHENIVTLYDVIHTENKLTLVFEYMDKD-LKKYMEVHGQQSA 102 Query 708 MAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV--- 762 + K+V + QL + + + ++H ++ +N+L+ G +KL D G+ Sbjct 103 LDLKVVKSFMFQLLKGIMFCHDNRVLHRDLKPQNLLINNKGE-------LKLGDFGLARA 155 Query 763 -GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 G+ + V + + AP+ L G + + +T++D W G E+C Sbjct 156 FGIPFNTFSNEVVTLWYRAPDVLLG-SRAYTTSIDIWSAGCIFAEMC 201 >sp|Q9NYV4|CDK12_HUMAN Cyclin-dependent kinase 12 OS=Homo sapiens OX=9606 GN=CDK12 PE=1 SV=2 Length=1490 Score = 90.1 bits (222), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 67/215 (31%), Positives = 101/215 (47%), Gaps = 37/215 (17%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958 +GEG +G+V Y + TGE+VA+K ++ D + G+ +EI ILR L H Sbjct 733 IGEGTYGQV----YKAKDKDTGELVALKKVRLD---NEKEGFPITAIREIKILRQLIHRS 785 Query 959 IIKYKGCCEDQGEK--------SLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQI 1007 ++ K D+ + + LV EY+ +G L L S + F +Q+ Sbjct 786 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSED--HIKSFMKQL 843 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED----GDS 1063 EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ Y E Sbjct 844 MEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLAR-------LYNSEESRPYTNKV 896 Query 1064 PVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096 WY P L E ++ A DVWS G L EL T Sbjct 897 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFT 931 Score = 35.8 bits (81), Expect = 3.5, Method: Compositional matrix adjust. Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 16/129 (12%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILL 742 +V EY++H D+ E G V + + + +QL L Y KN +H ++ NILL Sbjct 811 LVFEYMDH---DLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILL 867 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKW 798 G IKL+D G+ S E R ++ W P L G + A+D W Sbjct 868 NNSGQ-------IKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVW 920 Query 799 GFGATLLEI 807 G L E+ Sbjct 921 SCGCILGEL 929 >sp|Q5R4L1|PLK2_PONAB Serine/threonine-protein kinase PLK2 OS=Pongo abelii OX=9601 GN=PLK2 PE=3 SV=1 Length=685 Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 76/283 (27%), Positives = 130/283 (46%), Gaps = 32/283 (11%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWK 945 DPT KRY + + LG+G F K CY+ T+ ++ A K + P R Sbjct 75 DPTT-GKRYCRG-KVLGKGGFAK----CYEMTDLTNNKVYAAKIIPHSRVAKPHQREKID 128 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFA 1004 +EI++ R L+H+H++++ ED+ +++ +++EY S+ L R + ++ + Sbjct 129 KEIELHRILHHKHVVQFYHYFEDK--ENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 186 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDS 1063 +QI G+ YLH Q +HRDL N ++ +K+GDFGLA + P H R R + Sbjct 187 RQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEH---RRRTICGT 243 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 P + +PE L + SD+W+ G +Y + L+G + T L+ Sbjct 244 PNYL-SPEVLNKQGHGCESDIWALGCVMYTM----------------LLGRPPFETTNLK 286 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 T R R P HL+ + RP+ +++I Sbjct 287 ETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDII 329 >sp|Q8RWC9|CIPK1_ARATH CBL-interacting serine/threonine-protein kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CIPK1 PE=1 SV=2 Length=444 Score = 87.8 bits (216), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 74/208 (36%), Positives = 106/208 (51%), Gaps = 23/208 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRS-GWKQEIDILRTLYHEH 958 R LGEG+FGKV + D +G AVK + K+ + S K+EI L+ L H H Sbjct 24 RTLGEGNFGKVK-FAKDTV---SGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLKHPH 79 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQ 1017 I++ + + + +VME V G L D + + + QQ+ +G++Y H++ Sbjct 80 IVRLHEVLASKTK--INMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSK 137 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG------DSPVFWYAPE 1071 HRDL NVLLD +KI DFGL+ A+P+ R+DG SP + APE Sbjct 138 GVFHRDLKLENVLLDAKGHIKITDFGLS-ALPQ-----HFRDDGLLHTTCGSP-NYVAPE 190 Query 1072 CLKEYKFY-YASDVWSFGVTLYELLTHC 1098 L + ASD+WS GV LY +LT C Sbjct 191 VLANRGYDGAASDIWSCGVILYVILTGC 218 Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust. Identities = 56/232 (24%), Positives = 90/232 (39%), Gaps = 32/232 (14%) Query 641 LKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-D 696 +K++D S + +L + + H H+ +H V + MV E V G L D Sbjct 48 VKIIDKSRIADLNFSLQIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFD 107 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 + + KM QQL +SY +K + H ++ N+LL G IK Sbjct 108 RIVSNGKLTETDGRKMF--QQLIDGISYCHSKGVFHRDLKLENVLLDAKG-------HIK 158 Query 757 LSDPGVGLGALSREERVERI--------PWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 ++D GL AL + R + + ++APE L A D W G +L + Sbjct 159 ITD--FGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRGYD-GAASDIWSCGV-ILYVI 214 Query 809 FDGEAPLQSRSPSEKEHFYQRQHR----LPEPSCPQLATLTSQCLTYEPTQR 856 G P R+ + YQ+ + +P P T+ + L P R Sbjct 215 LTGCLPFDDRNLAV---LYQKICKGDPPIPRWLSPGARTMIKRMLDPNPVTR 263 >sp|Q9Z1J2|NEK4_MOUSE Serine/threonine-protein kinase Nek4 OS=Mus musculus OX=10090 GN=Nek4 PE=1 SV=1 Length=792 Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 61/200 (31%), Positives = 101/200 (51%), Gaps = 10/200 (5%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +R +G G +G+V+L + DG ++ L+ + + R +QE +L L H +I Sbjct 9 MRVVGRGSYGEVTLVKH--RRDGKQYVIKKLNLR-NASSRERRAAEQEAQLLSQLKHPNI 65 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLHA 1016 + YK E G+ L +VM + G L L L +Q++ + QI + YLH Sbjct 66 VTYKESWEG-GDGLLYIVMGFCEGGDLYRKLKEQKGQLLPESQVVEWFVQIAMALQYLHE 124 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +H +HRDL +NV L ++K+GD G+A+ + E H G +P ++ +PE Sbjct 125 KHILHRDLKTQNVFLTRTNIIKVGDLGIARVL-ENHGDMASTLIG-TP-YYMSPELFSNK 181 Query 1077 KFYYASDVWSFGVTLYELLT 1096 + Y SDVW+ G +YE+ T Sbjct 182 PYNYKSDVWALGCCVYEMAT 201 Score = 42.0 bits (97), Expect = 0.042, Method: Compositional matrix adjust. Identities = 50/219 (23%), Positives = 95/219 (43%), Gaps = 18/219 (8%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEYVEHGPLDVWLRRERGHV-PMAW 710 A + A L+SQ+ H ++ + G + ++ V + E G L L+ ++G + P + Sbjct 49 AAEQEAQLLSQLKHPNI-VTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPESQ 107 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + Q+A AL YL K+++H ++ +N+ L R + IK+ D G+ + Sbjct 108 VVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNI-------IKVGDLGIARVLENHG 160 Query 771 ERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + + +++PE + + D W G + E+ A S Sbjct 161 DMASTLIGTPYYMSPELFSNKPYNYKS--DVWALGCCVYEMATLKHAFNAKDMNSLVYRI 218 Query 827 YQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + + +P+ +LA L L+ P +RPS R+ILR Sbjct 219 IEGKLPPMPKVYSTELAELIRTMLSRRPEERPSVRSILR 257 >sp|Q5QNM6|CIPKD_ORYSJ Putative CBL-interacting protein kinase 13 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK13 PE=3 SV=1 Length=511 Score = 88.6 bits (218), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 68/204 (33%), Positives = 104/204 (51%), Gaps = 24/204 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYHEH 958 LG+G+F KV Y N TGE VA+K ++ + +SG K+EI +LR + H H Sbjct 31 LGQGNFAKV----YHARNVATGEEVAIKVMEKE--KIFKSGLTAHIKREIAVLRRVRHPH 84 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I++ + + VMEYV G L + R + A + QQ+ +A+ HA+ Sbjct 85 IVQLYEVMATK--LRIYFVMEYVRGGELFARVARGRLPEADARRYFQQLVSAVAFCHARG 142 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WYAPECL 1073 HRD+ N+L+D+ +K+ DFGL+ AV +G +R DG F + APE L Sbjct 143 VFHRDIKPENLLVDDAGDLKVSDFGLS-AVADG-----MRRDGLFHTFCGTPAYVAPEVL 196 Query 1074 KEYKFYYA-SDVWSFGVTLYELLT 1096 + A +D+WS GV L+ L+ Sbjct 197 SRRGYDAAGADLWSCGVVLFVLMA 220 Score = 50.8 bits (120), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 55/218 (25%), Positives = 93/218 (43%), Gaps = 28/218 (13%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 +++ +V H H+ ++ V V EYV G L + R RG +P A QQL Sbjct 75 AVLRRVRHPHIVQLYEVMATKLRIYFVMEYVRGGEL--FARVARGRLPEADARRYFQQLV 132 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776 SA+++ + + H ++ N+L+ G +K+SD GL A++ R + + Sbjct 133 SAVAFCHARGVFHRDIKPENLLVDDAGD-------LKVSD--FGLSAVADGMRRDGLFHT 183 Query 777 -----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 ++APE L + A D W G L + G P Q R+ + Y++ H Sbjct 184 FCGTPAYVAPEVLSRRGYDAAGA-DLWSCGVVLF-VLMAGYLPFQDRNLA---GMYRKIH 238 Query 832 ----RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 R P+ P+L L L P +R + I+ + Sbjct 239 KGDFRCPKWFSPELIRLLRGVLVTNPQRRATAEGIMEN 276 >sp|Q9M0X5|CRK25_ARATH Cysteine-rich receptor-like protein kinase 25 OS=Arabidopsis thaliana OX=3702 GN=CRK25 PE=3 SV=1 Length=675 Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 85/283 (30%), Positives = 128/283 (45%), Gaps = 29/283 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG+V TGE VA+K L + Q +K E+D++ L H ++ K Sbjct 353 LGHGGFGEVY-----KGQLITGETVAIKRL-SQGSTQGAEEFKNEVDVVAKLQHRNLAKL 406 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 G C D EK LV E+VP SL +L R + + + I G+ YLH Sbjct 407 LGYCLDGEEK--ILVYEFVPNKSLDYFLFDNEKRRVLDWQRRYKIIEGIARGILYLHRDS 464 Query 1019 ---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074 IHRDL A N+LLD D KI DFG+A+ G + + + Y +PE Sbjct 465 RLTIIHRDLKASNILLDADMHPKISDFGMARIF--GVDQTQANTKRIVGTYGYMSPEYAI 522 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL------TELL 1128 K+ SDV+SFGV + EL+T +S F E G+ V +L EL+ Sbjct 523 HGKYSVKSDVYSFGVLVLELITGKKNSS-----FYEEDGLGDLVTYVWKLWVENSPLELV 577 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + R H+ C + ++S RP+ ++++ ++ + Sbjct 578 DEAMRGNFQTNEVIRCIHIALLCVQEDSSERPSMDDILVMMNS 620 Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 70/304 (23%), Positives = 121/304 (40%), Gaps = 50/304 (16%) Query 517 EGWGRSFPS-VRELGAALQGCLLRAGDDCFSL-RRCCLPQPGETSNLIIMRGARASPRTL 574 +G G++ V + + C+L G C+ L RR ET +L S TL Sbjct 276 KGKGKNLTVIVTAIAVPVSVCVLLLGAMCWLLARRRNNKLSAETEDL--DEDGITSTETL 333 Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 Q S + ++ + LG G VY+G+L + G Sbjct 334 QF-QFSAIEAATNKFSESNKLGHGGFGEVYKGQL-------------------ITGE--- 370 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 V +K L A F +++++ H +LA + G C+ G E I+V E+V + Sbjct 371 ---TVAIKRLSQGSTQGAEEFKNEVDVVAKLQHRNLAKLLGYCLDGEEKILVYEFVPNKS 427 Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAE 749 LD +L + W + + + +A + YL + ++H ++ NILL Sbjct 428 LDYFLFDNEKRRVLDWQRRYKIIEGIARGILYLHRDSRLTIIHRDLKASNILL------- 480 Query 750 GTSPFIKLSDPGVG--LGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGAT 803 K+SD G+ G + +RI +++PE G S+ + D + FG Sbjct 481 DADMHPKISDFGMARIFGVDQTQANTKRIVGTYGYMSPEYAIHGKYSVKS--DVYSFGVL 538 Query 804 LLEI 807 +LE+ Sbjct 539 VLEL 542 >sp|Q86AE1|Y9853_DICDI Probable serine/threonine-protein kinase DDB_G0271538 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0271538 PE=3 SV=1 Length=527 Score = 88.6 bits (218), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 82/290 (28%), Positives = 129/290 (44%), Gaps = 34/290 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--DCGPQHRSGWKQEIDILRTLYHEHI 959 ++G G FG+V Y G VAVK L P + +EI IL+ + H +I Sbjct 38 EIGRGSFGQVQKASY------FGTDVAVKQLSTLVSIDPDYFKFMLREIKILKGMRHPNI 91 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL---FAQQICEGMAYLHA 1016 ++Y G C +G +V EY+ G L ++ + L A I +YLH+ Sbjct 92 VQYIGACCHEGR--YMIVTEYIKGGDLHQFIKARGVSNISWTLRMKLALDIASAFSYLHS 149 Query 1017 QHYIHRDLAARNVLLDN--DRL--VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 + I RDL A+N+L+D D L K+ DFG A+ + +G + + G +PE Sbjct 150 KKVIFRDLKAKNILVDEIGDGLYRAKVIDFGFAR-IFDGKDTNNLTICGSENTM--SPEV 206 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL-LERG 1131 + + + DV+S+GV L EL+ C S + Q + T + ++ LE+ Sbjct 207 IVGSSYNDSCDVYSYGVLLLELI--CGSR----------VVKTQLKRTPMNAFDMNLEKA 254 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 E L P+ CP L K C RPTF+ ++ LK + + P Sbjct 255 EHLA-PESCPRAFMDLAKWCCSYNPKDRPTFKIVVEGLKVLTNQQLKDLP 303 Score = 73.9 bits (180), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 67/268 (25%), Positives = 118/268 (44%), Gaps = 15/268 (6%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G D + L +DP + L ++ + H ++ G C ++VTEY Sbjct 54 GTDVAVKQLSTLVSIDPDYFKFML---REIKILKGMRHPNIVQYIGACCHEGRYMIVTEY 110 Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 ++ G L +++ RG ++W +M +A +ASA SYL +K ++ ++ +NIL+ +G Sbjct 111 IKGGDLHQFIK-ARGVSNISWTLRMKLALDIASAFSYLHSKKVIFRDLKAKNILVDEIGD 169 Query 748 AEGTSPFIKLSDPGVGLGALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 + I + G + + ++PE + G +S + + D + +G LLE Sbjct 170 GLYRAKVIDFGFARIFDGKDTNNLTICGSENTMSPEVIVG--SSYNDSCDVYSYGVLLLE 227 Query 807 -ICFDGEAPLQ-SRSPSE--KEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRT 861 IC Q R+P + + +H PE SCP+ L C +Y P RP+F+ Sbjct 228 LICGSRVVKTQLKRTPMNAFDMNLEKAEHLAPE-SCPRAFMDLAKWCCSYNPKDRPTFKI 286 Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDP 889 ++ L L L D+ P DP Sbjct 287 VVEGLKVLTNQQLKDLPVKGKSKPYIDP 314 >sp|Q54L00|LIMKA_DICDI Probable LIM domain-containing serine/threonine-protein kinase DDB_G0287001 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0287001 PE=3 SV=1 Length=650 Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 72/255 (28%), Positives = 115/255 (45%), Gaps = 24/255 (9%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH--IIKYKGCCEDQGEKSLQLVMEYV 981 G VA+K ++ + + +E+ I+ + +H ++ G Q +K L V E V Sbjct 407 GRDVAIKVYSSENFCFNIEEFDREVTIMSLIDSDHPNFTRFYGA-NKQNKKYLFHVSELV 465 Query 982 PLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 GSLRD L LA L A I M +LH+ IHRDL + NVL+ D K+ Sbjct 466 KSGSLRDLLLDKEKPLAYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKV 525 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFG ++ V + G S + +PE K + DV++FG+ L+E++ Sbjct 526 IDFGTSRNVDLAKQM--TLNLGTS--CYMSPELFKGNGYDETCDVYAFGIVLWEII---- 577 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 ++ P + + + L+ +GER P CP E L+K CW + R Sbjct 578 -ARKEPYE----------NINSWSIPVLVAKGERPTIPADCPSEYSKLIKACWTDKPKKR 626 Query 1160 PTFENLIPILKTVHE 1174 P+F+ + LK + E Sbjct 627 PSFKEICDTLKKISE 641 Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 56/228 (25%), Positives = 104/228 (46%), Gaps = 28/228 (12%) Query 655 FYETASLMSQVSHTHLAFV--HGVCVRGPENIM-VTEYVEHGPL-DVWLRRERGHVPMAW 710 F ++MS + H F +G + + + V+E V+ G L D+ L +E+ P+A+ Sbjct 427 FDREVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSELVKSGSLRDLLLDKEK---PLAY 483 Query 711 --KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDP-GVG 763 ++ +A +A+A+ +L + ++H ++ N+L+ A+ GTS + L+ + Sbjct 484 FTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLAKQMTLN 543 Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 LG +++PE G N D + FG L EI E P ++ + Sbjct 544 LGTSC---------YMSPELFKG--NGYDETCDVYAFGIVLWEIIARKE-PYENINSWSI 591 Query 824 EHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + R P+ CP + + L C T +P +RPSF+ I L ++ Sbjct 592 PVLVAKGERPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTLKKI 639 >sp|Q9NYY3|PLK2_HUMAN Serine/threonine-protein kinase PLK2 OS=Homo sapiens OX=9606 GN=PLK2 PE=1 SV=3 Length=685 Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 76/283 (27%), Positives = 130/283 (46%), Gaps = 32/283 (11%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWK 945 DPT KRY + + LG+G F K CY+ T+ ++ A K + P R Sbjct 75 DPTT-GKRYCRG-KVLGKGGFAK----CYEMTDLTNNKVYAAKIIPHSRVAKPHQREKID 128 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFA 1004 +EI++ R L+H+H++++ ED+ +++ +++EY S+ L R + ++ + Sbjct 129 KEIELHRILHHKHVVQFYHYFEDK--ENIYILLEYCSRRSMAHILKARKVLTEPEVRYYL 186 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDS 1063 +QI G+ YLH Q +HRDL N ++ +K+GDFGLA + P H R R + Sbjct 187 RQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEH---RRRTICGT 243 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 P + +PE L + SD+W+ G +Y + L+G + T L+ Sbjct 244 PNYL-SPEVLNKQGHGCESDIWALGCVMYTM----------------LLGRPPFETTNLK 286 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 T R R P HL+ + RP+ +++I Sbjct 287 ETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDII 329 >sp|Q86HN7|PLK_DICDI Probable serine/threonine-protein kinase PLK OS=Dictyostelium discoideum OX=44689 GN=PLK PE=3 SV=1 Length=978 Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 65/197 (33%), Positives = 100/197 (51%), Gaps = 15/197 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960 LG+G F K CY T T + A K + + RS K EI I +L HE+I+ Sbjct 169 LGKGGFAK----CYLMTEVETNRIYAAKIIPKSTLQKTRARSKLKSEIKIHSSLSHENIV 224 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 K++ C E+ E+++ +++E ++ D + R + + + Q+ + YLH + Sbjct 225 KFEHCFEN--EENVYILLELCNQKTVMDIHKKRKYLMEYETKYYVYQVIMAVQYLHNNNI 282 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRDL N+ +DN R +K+GDFGL+ V G R + +P + APE L + Sbjct 283 IHRDLKLGNLFIDNMR-IKLGDFGLSTKVEHGE---RKKTICGTPNYI-APEILDNSNGH 337 Query 1080 -YASDVWSFGVTLYELL 1095 Y DVWS G+ LY LL Sbjct 338 SYEVDVWSIGIILYTLL 354 Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 53/214 (25%), Positives = 95/214 (44%), Gaps = 27/214 (13%) Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 + S +SH ++ F H C EN+ + + + + + ++R ++ Q+ Sbjct 214 IHSSLSHENIVKFEH--CFENEENVYILLELCNQKTVMDIHKKRKYLMEYETKYYVYQVI 271 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776 A+ YL N N++H ++ N+ + + IKL D G+ + ER + I Sbjct 272 MAVQYLHNNNIIHRDLKLGNLFIDNMR--------IKLGDFGLS-TKVEHGERKKTICGT 322 Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR--QHRL 833 ++APE L +N S +D W G L + G+ P ++ S+ +H YQR Q++ Sbjct 323 PNYIAPEIL-DNSNGHSYEVDVWSIGIILYTLLI-GKPPFET---SDVKHTYQRIKQNQY 377 Query 834 PEPSCPQLA----TLTSQCLTYEPTQRPSFRTIL 863 P P ++ +L L P QRP+ IL Sbjct 378 SFPDEPIISHYGKSLIISILNPVPEQRPNLTQIL 411 >sp|D2H526|CDK12_AILME Cyclin-dependent kinase 12 OS=Ailuropoda melanoleuca OX=9646 GN=CDK12 PE=3 SV=1 Length=1491 Score = 89.7 bits (221), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 67/215 (31%), Positives = 101/215 (47%), Gaps = 37/215 (17%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958 +GEG +G+V Y + TGE+VA+K ++ D + G+ +EI ILR L H Sbjct 734 IGEGTYGQV----YKAKDKDTGELVALKKVRLD---NEKEGFPITAIREIKILRQLIHRS 786 Query 959 IIKYKGCCEDQGEK--------SLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQI 1007 ++ K D+ + + LV EY+ +G L L S + F +Q+ Sbjct 787 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSED--HIKSFMKQL 844 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED----GDS 1063 EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ Y E Sbjct 845 MEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLAR-------LYNSEESRPYTNKV 897 Query 1064 PVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096 WY P L E ++ A DVWS G L EL T Sbjct 898 ITLWYRPPELLLGEERYTPAIDVWSCGCILGELFT 932 Score = 35.8 bits (81), Expect = 3.2, Method: Compositional matrix adjust. Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 16/129 (12%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILL 742 +V EY++H D+ E G V + + + +QL L Y KN +H ++ NILL Sbjct 812 LVFEYMDH---DLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILL 868 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKW 798 G IKL+D G+ S E R ++ W P L G + A+D W Sbjct 869 NNSGQ-------IKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVW 921 Query 799 GFGATLLEI 807 G L E+ Sbjct 922 SCGCILGEL 930 >sp|Q9SJT0|Y2214_ARATH Probable receptor-like protein kinase At2g21480 OS=Arabidopsis thaliana OX=3702 GN=At2g21480 PE=3 SV=1 Length=871 Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 71/203 (35%), Positives = 96/203 (47%), Gaps = 24/203 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHEHI 959 +G G FG V + D DGT VA+K PQ G + EI +L L H H+ Sbjct 531 IGVGGFGNVYIGTID---DGT--QVAIKR----GNPQSEQGITEFHTEIQMLSKLRHRHL 581 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAYLH- 1015 + G C++ E + LV EY+ G RD+L ++ Q L G+ YLH Sbjct 582 VSLIGYCDENAE--MILVYEYMSNGPFRDHLYGKNLSPLTWKQRLEICIGAARGLHYLHT 639 Query 1016 --AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072 AQ IHRD+ + N+LLD + K+ DFGL+K V G + G F Y PE Sbjct 640 GTAQGIIHRDVKSTNILLDEALVAKVADFGLSKDVAFGQNHVSTAVKGS---FGYLDPEY 696 Query 1073 LKEYKFYYASDVWSFGVTLYELL 1095 + + SDV+SFGV L E L Sbjct 697 FRRQQLTDKSDVYSFGVVLLEAL 719 Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 68/297 (23%), Positives = 117/297 (39%), Gaps = 39/297 (13%) Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651 LS L + T+ + V G G+ G +DD +V +K +P Sbjct 515 LSELQEVTKNFDASEIIGVGGFGNVYIGTIDDG------------TQVAIKRGNPQSEQG 562 Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711 F+ ++S++ H HL + G C E I+V EY+ +GP L + P+ WK Sbjct 563 ITEFHTEIQMLSKLRHRHLVSLIGYCDENAEMILVYEYMSNGPFRDHLYG-KNLSPLTWK 621 Query 712 --MVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + + A L YL + ++H +V NILL L + F D G Sbjct 622 QRLEICIGAARGLHYLHTGTAQGIIHRDVKSTNILLDE-ALVAKVADFGLSKDVAFGQNH 680 Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE-IC----FDGEAPLQSRSPS 821 +S + +L PE L+ D + FG LLE +C + + P + + + Sbjct 681 VSTAVK-GSFGYLDPEYFR--RQQLTDKSDVYSFGVVLLEALCARPAINPQLPREQVNLA 737 Query 822 EKEHFYQRQ---HRLPEP---------SCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 E ++++ ++ +P S + A +CL RP+ +L +L Sbjct 738 EWAMLWKQKGLLEKIIDPHLVGAVNPESMKKFAEAAEKCLADYGVDRPTMGDVLWNL 794 >sp|O64793|Y1675_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g67520 OS=Arabidopsis thaliana OX=3702 GN=At1g67520 PE=2 SV=3 Length=818 Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 75/201 (37%), Positives = 101/201 (50%), Gaps = 18/201 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG V Y N GE VA+K L G Q +K E ++ L H ++++ Sbjct 502 LGEGGFGPV--YKGKLLN---GEEVAIKRLSLASG-QGLVEFKNEAILIAKLQHTNLVQV 555 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLF--AQQICEGMAYLHAQ- 1017 GCC ++ EK L+ EY+ SL +L P L L F + I +G+ YLH Sbjct 556 LGCCIEKDEK--MLIYEYMQNKSLDYFLFDPLRKNVLDWTLRFRIMEGIIQGLLYLHKYS 613 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074 IHRD+ A N+LLD D KI DFGLA+ G E R + F Y +PE + Sbjct 614 RLKVIHRDIKASNILLDEDMNPKISDFGLARIF--GAEETRANTKRVAGTFGYMSPEYFR 671 Query 1075 EYKFYYASDVWSFGVTLYELL 1095 E F SDV+SFGV + E++ Sbjct 672 EGLFSAKSDVFSFGVLMLEII 692 Score = 52.4 bits (124), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 21/193 (11%) Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 P+ G+ E V +K L + + F A L++++ HT+L V G C+ E ++ Sbjct 509 PVYKGKLLNGE-EVAIKRLSLASGQGLVEFKNEAILIAKLQHTNLVQVLGCCIEKDEKML 567 Query 686 VTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNI 740 + EY+++ LD +L + W + + + + L YL + ++H ++ NI Sbjct 568 IYEYMQNKSLDYFLFDPLRKNVLDWTLRFRIMEGIIQGLLYLHKYSRLKVIHRDIKASNI 627 Query 741 LLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIP----WLAPECLPGGANSLSTA 794 L L E +P K+SD G+ GA +R+ +++PE G S Sbjct 628 L-----LDEDMNP--KISDFGLARIFGAEETRANTKRVAGTFGYMSPEYFREGL--FSAK 678 Query 795 MDKWGFGATLLEI 807 D + FG +LEI Sbjct 679 SDVFSFGVLMLEI 691 >sp|Q5ZJB4|IKKA_CHICK Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Gallus gallus OX=9031 GN=CHUK PE=2 SV=1 Length=759 Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 66/212 (31%), Positives = 104/212 (49%), Gaps = 25/212 (12%) Query 899 KIRD-LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 ++RD LG G FG V LY + TG VA+K+ + + +++ W EIDI++ L H Sbjct 30 EMRDRLGTGGFGNVCLY----QHQDTGARVAIKSCRLELSVKNKDRWCHEIDIMKKLNHP 85 Query 958 HIIKYKGCCEDQGEKSL------QLVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQI 1007 ++++ CE E + L MEY G LR L P + GL +Q+L I Sbjct 86 NVVR---ACEVPEEMNFLVNDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDI 142 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDND--RLV-KIGDFGLAKAVPEGHEYYRVREDGDSP 1064 G+ YLH IHRDL N++L ++ +++ KI D G AK + +G + Sbjct 143 GSGIQYLHENRIIHRDLKPENIVLQDEGGKIIHKIIDLGYAKDLDQG----SLCTSFVGT 198 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 + + APE + + D WSFG ++E + Sbjct 199 LQYLAPELFENKSYSVTVDYWSFGTMVFECIA 230 >sp|Q2ULU3|STE20_ASPOR Serine/threonine-protein kinase ste20 OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=ste20 PE=3 SV=1 Length=848 Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 57/208 (27%), Positives = 102/208 (49%), Gaps = 14/208 (7%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DPT K Y + +G+G G V + ++GTG VA+K + D P+ + E Sbjct 562 DPT---KMYYN-LNKIGQGASGGV----FTAYHNGTGSCVAIKQMNLDLQPK-KDLIINE 612 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +++ H++I+ + + L +VMEY+ GSL D + + + Q+ ++ Sbjct 613 IIVMKDSKHKNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMSEGQIAAVCRET 670 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 G+ +LH++ IHRD+ + N+LL D +K+ DFG + + H R +W Sbjct 671 LNGLQHLHSKGVIHRDIKSDNILLSLDGNIKLTDFGFCAQINDSHNK---RNTMVGTPYW 727 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095 APE + ++ D+WS G+ E++ Sbjct 728 MAPEVVTRKEYGRKVDIWSLGIMAIEMI 755 Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust. Identities = 42/165 (25%), Positives = 69/165 (42%), Gaps = 18/165 (11%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719 +M H ++ + G + +V EY+E G L DV +A V ++ Sbjct 615 VMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVVTFNIMSEGQIA---AVCRETL 671 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERVER 775 + L +L +K ++H ++ NILL+ G IKL+D G + R V Sbjct 672 NGLQHLHSKGVIHRDIKSDNILLSLDG-------NIKLTDFGFCAQINDSHNKRNTMVGT 724 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 W+APE + +D W G +E+ +GE P + SP Sbjct 725 PYWMAPEVV--TRKEYGRKVDIWSLGIMAIEM-IEGEPPYLTESP 766 >sp|Q8GZ99|HPCA1_ARATH Leucine-rich repeat receptor protein kinase HPCA1 OS=Arabidopsis thaliana OX=3702 GN=HPCA1 PE=1 SV=1 Length=953 Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 62/181 (34%), Positives = 96/181 (53%), Gaps = 12/181 (7%) Query 923 TGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 G+++A+K +A G Q +K EI++L ++H+++++ G C D+ E+ LV EY+ Sbjct 652 NGQLIAIK--RAQQGSLQGGLEFKTEIELLSRVHHKNVVRLLGFCFDRNEQ--MLVYEYI 707 Query 982 PLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDR 1035 GSL+D L S + + L A +G+AYLH IHRD+ + N+LLD + Sbjct 708 SNGSLKDSLSGKSGIRLDWTRRLKIALGSGKGLAYLHELADPPIIHRDIKSNNILLDENL 767 Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 K+ DFGL+K V + E V + + PE + SDV+ FGV L ELL Sbjct 768 TAKVADFGLSKLVGD-PEKTHVTTQVKGTMGYLDPEYYMTNQLTEKSDVYGFGVVLLELL 826 Query 1096 T 1096 T Sbjct 827 T 827 Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 64/289 (22%), Positives = 114/289 (39%), Gaps = 60/289 (21%) Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW- 710 L F L+S+V H ++ + G C E ++V EY+ +G L L + G + + W Sbjct 669 GLEFKTEIELLSRVHHKNVVRLLGFCFDRNEQMLVYEYISNGSLKDSLSGKSG-IRLDWT 727 Query 711 -KMVVAQQLASALSY---LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--L 764 ++ +A L+Y L + ++H ++ NILL A K++D G+ + Sbjct 728 RRLKIALGSGKGLAYLHELADPPIIHRDIKSNNILLDENLTA-------KVADFGLSKLV 780 Query 765 GALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 G + ++ +L PE N L+ D +GFG LLE+ L RSP Sbjct 781 GDPEKTHVTTQVKGTMGYLDPEYYM--TNQLTEKSDVYGFGVVLLEL-------LTGRSP 831 Query 821 SEKEHFYQRQHRLPEPSCPQL------------------------ATLTSQCLTYEPTQR 856 E+ + R+ + L L +C+ E R Sbjct 832 IERGKYVVREVKTKMNKSRSLYDLQELLDTTIIASSGNLKGFEKYVDLALRCVEEEGVNR 891 Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 PS +++++ N+ + +NP+ SD + Y I+ G+ Sbjct 892 PSMGEVVKEI-----ENIMQLAGLNPN---SDSATSSRTYEDAIKGSGD 932 >sp|E1BB50|CDK12_BOVIN Cyclin-dependent kinase 12 OS=Bos taurus OX=9913 GN=CDK12 PE=3 SV=1 Length=1264 Score = 89.4 bits (220), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 67/213 (31%), Positives = 101/213 (47%), Gaps = 33/213 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958 +GEG +G+V Y + TGE+VA+K ++ D + G+ +EI ILR L H Sbjct 733 IGEGTYGQV----YKAKDKDTGELVALKKVRLD---NEKEGFPITAIREIKILRQLIHRS 785 Query 959 IIKYKGCCEDQGEK--------SLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQI 1007 ++ K D+ + + LV EY+ +G L L S + F +Q+ Sbjct 786 VVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSED--HIKSFMKQL 843 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK--AVPEGHEYYRVREDGDSPV 1065 EG+ Y H ++++HRD+ N+LL+N +K+ DFGLA+ E Y Sbjct 844 MEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYT-----NKVIT 898 Query 1066 FWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096 WY P L E ++ A DVWS G L EL T Sbjct 899 LWYRPPELLLGEERYTPAIDVWSCGCILGELFT 931 Score = 36.2 bits (82), Expect = 2.6, Method: Compositional matrix adjust. Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 16/129 (12%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILL 742 +V EY++H D+ E G V + + + +QL L Y KN +H ++ NILL Sbjct 811 LVFEYMDH---DLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILL 867 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREER--VERIP--WLAPECLPGGANSLSTAMDKW 798 G IKL+D G+ S E R ++ W P L G + A+D W Sbjct 868 NNSGQ-------IKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVW 920 Query 799 GFGATLLEI 807 G L E+ Sbjct 921 SCGCILGEL 929 >sp|Q6BRY2|PHO85_DEBHA Negative regulator of the PHO system OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=PHO85 PE=3 SV=2 Length=330 Score = 85.9 bits (211), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 61/206 (30%), Positives = 100/206 (49%), Gaps = 17/206 (8%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +++ LGEG + V Y N G++VA+K + D S +EI +++ L H Sbjct 8 FQQLEKLGEGTYATV----YKGRNRTNGQLVALKEINLDSEEGTPSTAIREISLMKELDH 63 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----SIGLAQLLLFAQQICEGMA 1012 E+I+ E L LV E++ L+ Y+ H ++ L + F Q+ +G+ Sbjct 64 ENIVTLYDVI--HTENKLTLVFEFMD-KDLKKYMEAHGNQGALDLKIVKSFIFQLLKGIM 120 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APE 1071 + H +HRDL +N+L++N +K+GDFGLA+A + + WY AP+ Sbjct 121 FCHDNRVLHRDLKPQNLLINNKGELKLGDFGLARAFGIPFNTF----SNEVVTLWYRAPD 176 Query 1072 CLKEYKFYYAS-DVWSFGVTLYELLT 1096 L + Y AS D+WS G E+ T Sbjct 177 VLLGSRAYTASIDIWSAGCIFAEMCT 202 Score = 38.9 bits (89), Expect = 0.23, Method: Compositional matrix adjust. Identities = 48/227 (21%), Positives = 93/227 (41%), Gaps = 38/227 (17%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + QL LG+GT VY+GR R GQ + + LD Sbjct 7 QFQQLEKLGEGTYATVYKGR----------------------NRTNGQLVALKEINLDSE 44 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 + A E SLM ++ H ++ ++ V + +V E+++ L ++ Sbjct 45 EGTPSTAIREI-SLMKELDHENIVTLYDVIHTENKLTLVFEFMDKD-LKKYMEAHGNQGA 102 Query 708 MAWKMVVAQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV--- 762 + K+V + QL + + + ++H ++ +N+L+ G +KL D G+ Sbjct 103 LDLKIVKSFIFQLLKGIMFCHDNRVLHRDLKPQNLLINNKGE-------LKLGDFGLARA 155 Query 763 -GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 G+ + V + + AP+ L G + + + ++D W G E+C Sbjct 156 FGIPFNTFSNEVVTLWYRAPDVLLG-SRAYTASIDIWSAGCIFAEMC 201 >sp|Q05006|CDC22_MEDSA Cell division control protein 2 homolog 2 OS=Medicago sativa OX=3879 GN=CDC2B PE=2 SV=1 Length=294 Score = 85.1 bits (209), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 65/208 (31%), Positives = 102/208 (49%), Gaps = 20/208 (10%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYH 956 +K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ + H Sbjct 5 EKVEKIGEGTYGVV----YKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLG--SLRDYLPRHSIGLAQLLLFAQQICEGMAYL 1014 +I++ + EK L LV EY+ L D P + Q+ +F QI G+AY Sbjct 61 RNIVRLQDVV--HSEKRLYLVFEYLDLDLKKFMDSSPEFAKDQRQIKMFLYQILCGIAYC 118 Query 1015 HAQHYIHRDLAARNVLLD-NDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070 H+ +HRDL +N+L+D + VK+ DFGLA+A +P + V WY AP Sbjct 119 HSHRVLHRDLKPQNLLIDRSSNAVKLADFGLARAFGIPVRTFTHEV------VTLWYRAP 172 Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTH 1097 E L + Y DVWS G E++ Sbjct 173 EILLGSRHYSTPVDVWSVGCIFAEMINQ 200 >sp|P34331|PLK1_CAEEL Serine/threonine-protein kinase plk-1 OS=Caenorhabditis elegans OX=6239 GN=plk-1 PE=1 SV=3 Length=649 Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 73/218 (33%), Positives = 110/218 (50%), Gaps = 14/218 (6%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQH 940 P+ PA Y +K R LG+G F +CY+ TN T E+VA K + K+ Q+ Sbjct 23 PEVPALIADKDRGTYYEKGRFLGKGGFA----HCYELTNRATREVVAGKVVPKSMLVKQY 78 Query 941 RSGW--KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGL 997 + + I I R L H +I+K ED ++ + +E SL + + R ++ Sbjct 79 QRDKVDNERILIHRELGHINIVKLFNFFEDN--LNVYITLELCARRSLMELHKRRKAVTE 136 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + F QI +G+ YLH + IHRD+ N+ L++D +VKIGDFGLA V G E R Sbjct 137 PEARYFTHQIVDGVLYLHDLNIIHRDMKLGNLFLNDDLVVKIGDFGLATTV-NGDE--RK 193 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 + +P + APE L + + D+W+ G LY LL Sbjct 194 KTLCGTPN-YIAPEVLNKAGHSFEVDIWAVGCILYILL 230 Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 43/172 (25%), Positives = 77/172 (45%), Gaps = 16/172 (9%) Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 L + R V Q+ + YL + N++H R++ L L L + +K+ Sbjct 127 LHKRRKAVTEPEARYFTHQIVDGVLYLHDLNIIH-----RDMKLGNLFLNDDL--VVKIG 179 Query 759 DPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 D G+ ++ +ER + + ++APE L +S +D W G L + F G+ P Sbjct 180 DFGLAT-TVNGDERKKTLCGTPNYIAPEVLNKAGHSFE--VDIWAVGCILYILLF-GQPP 235 Query 815 LQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 +S+S E + +P + A+L + L EPT+RP+ + + RD Sbjct 236 FESKSLEETYSRIRHNNYTIPSIATQPAASLIRKMLDPEPTRRPTAKQVQRD 287 >sp|Q9R0A5|NEK3_MOUSE Serine/threonine-protein kinase Nek3 OS=Mus musculus OX=10090 GN=Nek3 PE=1 SV=2 Length=511 Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 73/270 (27%), Positives = 125/270 (46%), Gaps = 29/270 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +R +G+G FG+ L + +N T M ++ LK+D ++E +L + H +I Sbjct 7 LRVIGQGSFGRALLVLQESSNQ-TFAMKEIRLLKSDTQTS-----RKEAVLLAKMKHPNI 60 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLHA 1016 + +K E +G L +VMEY G L + + L +L + QIC G+ ++H Sbjct 61 VAFKESFEAEG--YLYIVMEYCDGGDLMQRIKQQKGKLFPEDTILNWFIQICLGVNHIHK 118 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + +HRD+ ++NV L ++ VK+GDFG A+ + + +P ++ PE + Sbjct 119 RRVLHRDIKSKNVFLTHNGKVKLGDFGSARLLSSPMAFACTYV--GTP-YYVPPEIWENL 175 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 + SD+WS G LYEL Q+ K L ++ I QG + P Sbjct 176 PYNNKSDIWSLGCILYELCALKHPFQANSWKNL-ILKICQGPIH--------------PL 220 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 P C++ L+K + S RP+ L+ Sbjct 221 PALYSCKLQGLVKQMLKRNPSHRPSATTLL 250 >sp|O54748|STK3_RAT Serine/threonine-protein kinase 3 OS=Rattus norvegicus OX=10116 GN=Stk3 PE=1 SV=1 Length=491 Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 56/197 (28%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V + + +G++VA+K + + Q +EI I++ ++ Sbjct 30 LEKLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDVQE---IIKEISIMQQCDSPYV 82 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ + +G+ YLH Sbjct 83 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFM 140 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 141 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVIQEIG 197 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 198 YNCVADIWSLGITSIEM 214 >sp|Q4G3H4|IKKA_DANRE Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Danio rerio OX=7955 GN=chuk PE=1 SV=1 Length=758 Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 64/202 (32%), Positives = 96/202 (48%), Gaps = 19/202 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V LY N T E +AVK + + +++ W + I I++ L H +++ Sbjct 21 LGTGGFGHVYLY----QNQETSEKIAVKLCRLELNSKNKDRWSRGIQIMKKLKHLNVVTA 76 Query 963 KGCCEDQGEKSLQ----LVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMAYL 1014 K E+ +L L MEY G LR L P + GL +++L + G+ YL Sbjct 77 KDVPEEMMHIALNDLPLLAMEYCSKGDLRKLLSKPENCCGLKESEVLSLLNDVGSGIQYL 136 Query 1015 HAQHYIHRDLAARNVLLD--NDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 H IHRDL N++L N +LV KI D G AK + +G + + + APE Sbjct 137 HENKIIHRDLKPENIVLQEINGKLVHKIIDLGYAKDLDQGS----LCTSFVGTLQYLAPE 192 Query 1072 CLKEYKFYYASDVWSFGVTLYE 1093 + + D WSFG ++E Sbjct 193 LFEGKSYTVTVDFWSFGTMIFE 214 >sp|Q6GM53|IKKA_XENLA Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Xenopus laevis OX=8355 GN=chuk PE=2 SV=1 Length=743 Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 67/206 (33%), Positives = 97/206 (47%), Gaps = 24/206 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V LY N TGE+ A+K+ + + +++ W QEI I++ L H +++K Sbjct 21 LGTGGFGNVCLY----QNRETGELKAIKSCRLELSVKNKERWCQEIQIMKRLNHPNVVK- 75 Query 963 KGCCEDQGEKSL------QLVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMA 1012 C+ E L MEY G LR L P + GL +Q+L I G+ Sbjct 76 --ACDVPPEMDFLVNDVPHLAMEYCAGGDLRKLLNKPENCCGLKESQVLNLISDIGSGIQ 133 Query 1013 YLHAQHYIHRDLAARNVLLD--NDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH IHRDL N++L N + V KI D G AK + +G + + + A Sbjct 134 YLHENRIIHRDLKPENIVLQECNGKTVHKIIDLGYAKDLDQGS----LCTSFVGTLQYLA 189 Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095 PE + + D WSFG +E + Sbjct 190 PELFENKPYSVTVDYWSFGTMAFECI 215 >sp|Q54QI2|Y9877_DICDI Serine/threonine-protein kinase DDB_G0283821 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0283821 PE=3 SV=1 Length=941 Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 63/198 (32%), Positives = 99/198 (50%), Gaps = 15/198 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G FGKV + N TG+ A+K + K + QEI +L+TL H +I+K Sbjct 19 VGKGAFGKV----FKALNAETGDFCAIKQIEKTIISEKQLPSIIQEIKLLQTLQHPNIVK 74 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLHAQHYI 1020 + E + L +E++ GSL R+ LL + Q+ +G+AYLH + I Sbjct 75 FIESYE--TSRYLYFALEFIEGGSLAKIAKRYGCFQEPLLSRYFSQVLKGLAYLHEKGVI 132 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK--EYKF 1078 HRD+ + N+L+ + ++K+ DFG + V +P FW APE ++ Sbjct 133 HRDIKSDNILITKEGVIKLADFGSCTYSAIDRKLTVV----GTP-FWMAPEVIQMDMNAR 187 Query 1079 YYASDVWSFGVTLYELLT 1096 A D+WS G TL E+LT Sbjct 188 STACDIWSLGCTLLEMLT 205 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 34/93 (37%), Positives = 50/93 (54%), Gaps = 9/93 (10%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-VGLGALSREERVER 775 Q+ L+YL K ++H ++ NIL+ + G+ IKL+D G A+ R+ V Sbjct 118 QVLKGLAYLHEKGVIHRDIKSDNILITKEGV-------IKLADFGSCTYSAIDRKLTVVG 170 Query 776 IP-WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 P W+APE + N+ STA D W G TLLE+ Sbjct 171 TPFWMAPEVIQMDMNARSTACDIWSLGCTLLEM 203 >sp|Q9STK6|WNK3_ARATH Probable serine/threonine-protein kinase WNK3 OS=Arabidopsis thaliana OX=3702 GN=WNK3 PE=2 SV=1 Length=516 Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 73/216 (34%), Positives = 109/216 (50%), Gaps = 19/216 (9%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD---CGPQHRSGW 944 DPT + RY K++ LG+G F +V Y + G VA +K D C + Sbjct 16 DPTGRYGRY-KEV--LGKGAFKEV----YRAFDQLEGIEVAWNQVKLDDKFCSSEDLDRL 68 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLF 1003 E+ +L+TL H+ IIK+ D ++ L+ E G+LR Y +H + L L + Sbjct 69 YSEVHLLKTLKHKSIIKFYTSWIDHQHMTINLITEVFTSGNLRQYRKKHKCVDLRALKKW 128 Query 1004 AQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 ++QI EG+ YLH+ IHRDL N+ ++ N VKIGD GLA + + V Sbjct 129 SRQILEGLVYLHSHDPPVIHRDLKCDNIFINGNQGEVKIGDLGLAAILHRARSAHSVI-- 186 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 +P F APE L E + D+++FG+ L EL+T Sbjct 187 -GTPEFM-APE-LYEEDYNVLVDIYAFGMCLLELVT 219 >sp|Q852Q1|OSK4_ORYSJ Serine/threonine protein kinase OSK4 OS=Oryza sativa subsp. japonica OX=39947 GN=OSK4 PE=1 SV=1 Length=509 Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 71/200 (36%), Positives = 97/200 (49%), Gaps = 16/200 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEH 958 R LG G FGKV + + TG VA+K L + + K+EI ILR H H Sbjct 21 RTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKREIKILRLFIHPH 76 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 II+ + + +VMEY G L DY+ + + + QQI G+ Y H Sbjct 77 IIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQIISGVEYCHRN 134 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL N+LLD+ VK+ DFGL+ + +GH ++ SP + APE + K Sbjct 135 MVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGH---FLKTSCGSPNYA-APEVISG-K 189 Query 1078 FYYA--SDVWSFGVTLYELL 1095 Y DVWS GV LY LL Sbjct 190 LYAGPEVDVWSCGVILYALL 209 >sp|B8BBT7|OSK4_ORYSI Serine/threonine protein kinase OSK4 OS=Oryza sativa subsp. indica OX=39946 GN=OSK4 PE=3 SV=1 Length=509 Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 71/200 (36%), Positives = 97/200 (49%), Gaps = 16/200 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEH 958 R LG G FGKV + + TG VA+K L + + K+EI ILR H H Sbjct 21 RTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKREIKILRLFIHPH 76 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 II+ + + +VMEY G L DY+ + + + QQI G+ Y H Sbjct 77 IIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQIISGVEYCHRN 134 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL N+LLD+ VK+ DFGL+ + +GH ++ SP + APE + K Sbjct 135 MVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGH---FLKTSCGSPNYA-APEVISG-K 189 Query 1078 FYYA--SDVWSFGVTLYELL 1095 Y DVWS GV LY LL Sbjct 190 LYAGPEVDVWSCGVILYALL 209 >sp|Q76P07|Y7165_DICDI Probable serine/threonine-protein kinase DDB_G0277165 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0277165 PE=3 SV=1 Length=833 Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 66/198 (33%), Positives = 99/198 (50%), Gaps = 9/198 (5%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 + LG+G GKV L + T G + K L + P R ++EI +++ + H + + Sbjct 13 KTLGQGTTGKVKLGFHKDTGFKVGIKIINKELLIN-KPSMRRKIEREIVLMKLIDHPNAM 71 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 K E K L L++EYV G L DYL + + + L F QQI G+ Y H+++ Sbjct 72 KMYEVYET--SKYLFLILEYVEGGELFDYLVEKGGLESGEALFFFQQIIIGLEYCHSRNI 129 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 HRDL N+LL D+ +KI DFG+ V + + SP + +PE + + Sbjct 130 CHRDLKPENLLLSGDKRIKIADFGMGSIV---RKDMLLHTSCGSP-HYASPEVVSGIDYD 185 Query 1080 -YASDVWSFGVTLYELLT 1096 +DVWS GV LY LLT Sbjct 186 GQKADVWSCGVILYALLT 203 Score = 38.1 bits (87), Expect = 0.56, Method: Compositional matrix adjust. Identities = 47/214 (22%), Positives = 90/214 (42%), Gaps = 30/214 (14%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 LM + H + ++ V ++ EYVE G L +L E+G + + QQ+ Sbjct 61 LMKLIDHPNAMKMYEVYETSKYLFLILEYVEGGELFDYLV-EKGGLESGEALFFFQQIII 119 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP--- 777 L Y ++N+ H ++ N+LL+ IK++D G+G++ R++ + Sbjct 120 GLEYCHSRNICHRDLKPENLLLS-------GDKRIKIAD--FGMGSIVRKDMLLHTSCGS 170 Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR--- 832 + +PE + G + D W G L A L + P + E+ + ++ Sbjct 171 PHYASPEVV-SGIDYDGQKADVWSCGVILY-------ALLTGKLPFDDENIRRLLNKVKN 222 Query 833 ----LPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 +P L ++ LT +P++R S + I Sbjct 223 GAFSMPPYIHKDAQDLLTKMLTVDPSKRISIKEI 256 >sp|Q9SX31|PERK9_ARATH Proline-rich receptor-like protein kinase PERK9 OS=Arabidopsis thaliana OX=3702 GN=PERK9 PE=1 SV=1 Length=708 Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 71/209 (34%), Positives = 103/209 (49%), Gaps = 20/209 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG C G +VAVK LK G R +K E++ L ++H H++ Sbjct 383 LGEGGFG-----CVYKGILPDGRVVAVKQLKIGGGQGDRE-FKAEVETLSRIHHRHLVSI 436 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ--- 1017 G C G++ L L+ +YV L +L + + A + A G+AYLH Sbjct 437 VGHC-ISGDRRL-LIYDYVSNNDLYFHLHGEKSVLDWATRVKIAAGAARGLAYLHEDCHP 494 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKEY 1076 IHRD+ + N+LL+++ ++ DFGLA+ + + + R G F Y APE Sbjct 495 RIIHRDIKSSNILLEDNFDARVSDFGLARLALDCNTHITTRVIG---TFGYMAPEYASSG 551 Query 1077 KFYYASDVWSFGVTLYELLTH---CDSSQ 1102 K SDV+SFGV L EL+T D+SQ Sbjct 552 KLTEKSDVFSFGVVLLELITGRKPVDTSQ 580 Score = 51.2 bits (121), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 45/182 (25%), Positives = 77/182 (42%), Gaps = 18/182 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F +S++ H HL + G C+ G +++ +YV + L L E+ + A ++ + Sbjct 418 FKAEVETLSRIHHRHLVSIVGHCISGDRRLLIYDYVSNNDLYFHLHGEKSVLDWATRVKI 477 Query 715 AQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771 A A L+YL ++H ++ NILL A ++SD G+ AL Sbjct 478 AAGAARGLAYLHEDCHPRIIHRDIKSSNILLEDNFDA-------RVSDFGLARLALDCNT 530 Query 772 RVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + ++APE G L+ D + FG LLE+ G P+ + P E Sbjct 531 HITTRVIGTFGYMAPEYASSG--KLTEKSDVFSFGVVLLEL-ITGRKPVDTSQPLGDESL 587 Query 827 YQ 828 + Sbjct 588 VE 589 >sp|Q07292|KRAF1_CAEEL Raf homolog serine/threonine-protein kinase OS=Caenorhabditis elegans OX=6239 GN=lin-45 PE=1 SV=2 Length=813 Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 72/280 (26%), Positives = 125/280 (45%), Gaps = 30/280 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y GT VA+K L D P + +K E+ +L+ H +++ Sbjct 487 VGSGSFGTV----YRGEFFGT---VAIKKLNVVDPTPSQMAAFKNEVAVLKKTRHLNVLL 539 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G E + ++ ++ SL ++ PR + ++ +Q+ GM YLH++ Sbjct 540 FMGWVR---EPEIAIITQWCEGSSLYRHIHVQEPRVEFEMGAIIDILKQVSLGMNYLHSK 596 Query 1018 HYIHRDLAARNV-LLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLK- 1074 + IHRDL N+ L+D+ VKIGDFGLA + + ++ + W APE ++ Sbjct 597 NIIHRDLKTNNIFLMDDMSTVKIGDFGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRM 656 Query 1075 --EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + SDV+SFG+ +YE+L + L I + + R + Sbjct 657 QDDNPYTPQSDVYSFGICMYEIL----------SSHLPYSNINNRDQILFMVGRGYLRPD 706 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 R P + L NC + + RP F ++ L+ + Sbjct 707 RSKIRHDTPKSMLKLYDNCIMFDRNERPVFGEVLERLRDI 746 Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 55/246 (22%), Positives = 104/246 (42%), Gaps = 31/246 (13%) Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVW 698 L V+DP+ +A AF +++ + H ++ G VR PE ++T++ E L + Sbjct 509 LNVVDPTPSQMA-AFKNEVAVLKKTRHLNVLLFMG-WVREPEIAIITQWCEGSSLYRHIH 566 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 ++ R M + + +Q++ ++YL +KN++H ++ NI L +K+ Sbjct 567 VQEPRVEFEMGAIIDILKQVSLGMNYLHSKNIIHRDLKTNNIFLM------DDMSTVKIG 620 Query 759 DPGVGLGALSREERVE----------RIPWLAPECLP-GGANSLSTAMDKWGFGATLLEI 807 D GL + + V I W+APE + N + D + FG + EI Sbjct 621 D--FGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGICMYEI 678 Query 808 CFDGEAPLQSRSPSEKEHF-----YQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFR 860 P + + ++ F Y R R + + + L C+ ++ +RP F Sbjct 679 -LSSHLPYSNINNRDQILFMVGRGYLRPDRSKIRHDTPKSMLKLYDNCIMFDRNERPVFG 737 Query 861 TILRDL 866 +L L Sbjct 738 EVLERL 743 >sp|Q9GRT1|MKK4_LEIME Putative mitogen-activated protein kinase kinase 4 OS=Leishmania mexicana OX=5665 GN=MKK4 PE=1 SV=2 Length=350 Score = 85.9 bits (211), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 63/216 (29%), Positives = 113/216 (52%), Gaps = 18/216 (8%) Query 885 PASDPTVFHKRYLKKIR---DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH- 940 P SD V +K + +R +LG+G GKV + + T GE A+K + D Sbjct 59 PKSD-AVMNKIKFEDLRIGSELGKGSQGKVRVAQHKLT----GEKYAMKYIAFDGDSDDM 113 Query 941 RSGWKQEIDILRTLYHEHIIK-YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ 999 RS + E+ + + H +++ Y+ D L +V+EY+ G++ + + RH G ++ Sbjct 114 RSALEAELRQVAAVKHHNVVSSYEAFFRD---GRLYIVLEYMDCGTMNNLIDRHPEGFSE 170 Query 1000 LLL--FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 +L A+++ +G+ +LH + IHRD+ NVL + +KI DFG+AK + G + + Sbjct 171 DMLAYIARELFKGLEFLHHLNMIHRDIKPANVLANTKGEIKISDFGVAKTL-SGGDLQTL 229 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 G P + +PE ++ + + SD+WS G+T+ E Sbjct 230 SAQGSVP--YMSPERIQSKPYSFNSDIWSAGLTIAE 263 Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust. Identities = 43/191 (23%), Positives = 77/191 (40%), Gaps = 14/191 (7%) Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 G++ + D D+ A ++ V H ++ + R +V EY++ G Sbjct 96 GEKYAMKYIAFDGDSDDMRSALEAELRQVAAVKHHNVVSSYEAFFRDGRLYIVLEYMDCG 155 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 ++ + R +A++L L +L + N++H ++ N+L T Sbjct 156 TMNNLIDRHPEGFSEDMLAYIARELFKGLEFLHHLNMIHRDIKPANVL-------ANTKG 208 Query 754 FIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 IK+SD GV G L +P+++PE + S ++ D W G T+ E F Sbjct 209 EIKISDFGVAKTLSGGDLQTLSAQGSVPYMSPERIQSKPYSFNS--DIWSAGLTIAECAF 266 Query 810 DGEAPLQSRSP 820 E P S P Sbjct 267 R-EYPFASLKP 276 >sp|Q9LQQ8|PBL5_ARATH Probable serine/threonine-protein kinase PBL5 OS=Arabidopsis thaliana OX=3702 GN=PBL5 PE=2 SV=1 Length=423 Score = 87.0 bits (214), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 89/300 (30%), Positives = 139/300 (46%), Gaps = 31/300 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FGKV + T + ++VA+K L + G Q + E+ L H +++K Sbjct 109 LGEGGFGKV----FKGTIEKLDQVVAIKQLDRN-GVQGIREFVVEVLTLSLADHPNLVKL 163 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017 G C +G++ L LV EY+P GSL D+L G L + A G+ YLH + Sbjct 164 IGFCA-EGDQRL-LVYEYMPQGSLEDHLHVLPSGKKPLDWNTRMKIAAGAARGLEYLHDR 221 Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG---HEYYRVREDGDSPVFWYAPE 1071 I+RDL N+LL D K+ DFGLAK P G H RV + AP+ Sbjct 222 MTPPVIYRDLKCSNILLGEDYQPKLSDFGLAKVGPSGDKTHVSTRVM----GTYGYCAPD 277 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIA----QGQMTVLRLTE 1126 + + SD++SFGV L EL+T + + T K L+G A + + ++ + Sbjct 278 YAMTGQLTFKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLFKDRRNFPKMVD 337 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV-HEKYQGQAPSVFS 1185 L +G+ P + + + C + + + RP +++ L + KY +PS S Sbjct 338 PLLQGQ---YPVRGLYQALAISAMCVQEQPTMRPVVSDVVLALNFLASSKYDPNSPSSSS 394 Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 64/274 (23%), Positives = 111/274 (41%), Gaps = 35/274 (13%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K LD + F +S H +L + G C G + ++V EY+ G L+ Sbjct 129 VAIKQLDRNGVQGIREFVVEVLTLSLADHPNLVKLIGFCAEGDQRLLVYEYMPQGSLEDH 188 Query 699 LR-RERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 L G P+ W +M +A A L YL ++ + V R++ + + L E P Sbjct 189 LHVLPSGKKPLDWNTRMKIAAGAARGLEYLHDR--MTPPVIYRDLKCSNILLGEDYQP-- 244 Query 756 KLSDPGVG-LGALSREERVE-RIPWLAPECLPGGA--NSLSTAMDKWGFGATLLEICFDG 811 KLSD G+ +G + V R+ C P A L+ D + FG LLE+ Sbjct 245 KLSDFGLAKVGPSGDKTHVSTRVMGTYGYCAPDYAMTGQLTFKSDIYSFGVVLLELITGR 304 Query 812 EAPLQSRSPSEKEH------FYQRQHRLPEPSCP------------QLATLTSQCLTYEP 853 +A +++ ++ ++ + P+ P Q +++ C+ +P Sbjct 305 KAIDNTKTRKDQNLVGWARPLFKDRRNFPKMVDPLLQGQYPVRGLYQALAISAMCVQEQP 364 Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 T RP ++ L L +P+SP+S Sbjct 365 TMRPVVSDVVLALNFLASSKY------DPNSPSS 392 >sp|Q9LK03|PERK2_ARATH Proline-rich receptor-like protein kinase PERK2 OS=Arabidopsis thaliana OX=3702 GN=PERK2 PE=2 SV=3 Length=717 Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 68/201 (34%), Positives = 98/201 (49%), Gaps = 18/201 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V G+ VAVK LK R ++ E+ I+ ++H H++ Sbjct 360 LGQGGFGYVFKGMLR-----NGKEVAVKQLKEGSSQGERE-FQAEVGIISRVHHRHLVAL 413 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 G C ++ LV E+VP +L +L R ++ + L A +G++YLH Sbjct 414 VGYCIADAQR--LLVYEFVPNNTLEFHLHGKGRPTMEWSSRLKIAVGSAKGLSYLHENCN 471 Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075 IHRD+ A N+L+D K+ DFGLAK + + + R G F Y APE Sbjct 472 PKIIHRDIKASNILIDFKFEAKVADFGLAKIASDTNTHVSTRVMG---TFGYLAPEYASS 528 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 K SDV+SFGV L EL+T Sbjct 529 GKLTEKSDVFSFGVVLLELIT 549 Score = 51.6 bits (122), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 68/266 (26%), Positives = 104/266 (39%), Gaps = 54/266 (20%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 P PG L I +G T N +LS ++ + LGQG V++G LR Sbjct 327 PSPGLALGLGIYQG------TFNYEELSRA---TNGFSEANLLGQGGFGYVFKGMLR--- 374 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672 G+E V +K L F ++S+V H HL Sbjct 375 --------------------NGKE--VAVKQLKEGSSQGEREFQAEVGIISRVHHRHLVA 412 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---N 727 + G C+ + ++V E+V + L+ L +G M W ++ +A A LSYL N Sbjct 413 LVGYCIADAQRLLVYEFVPNNTLEFHL-HGKGRPTMEWSSRLKIAVGSAKGLSYLHENCN 471 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPE 782 ++H ++ NIL+ A K++D G+ A V +LAPE Sbjct 472 PKIIHRDIKASNILIDFKFEA-------KVADFGLAKIASDTNTHVSTRVMGTFGYLAPE 524 Query 783 CLPGGANSLSTAMDKWGFGATLLEIC 808 G L+ D + FG LLE+ Sbjct 525 YASSG--KLTEKSDVFSFGVVLLELI 548 >sp|Q852Q0|OSK3_ORYSJ Serine/threonine protein kinase OSK3 OS=Oryza sativa subsp. japonica OX=39947 GN=OSK3 PE=1 SV=1 Length=508 Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 71/200 (36%), Positives = 97/200 (49%), Gaps = 16/200 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEH 958 R LG G FGKV + + TG VA+K L + + K+EI ILR H H Sbjct 21 RTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKREIKILRLFIHPH 76 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 II+ + + +VMEY G L DY+ + + + QQI G+ Y H Sbjct 77 IIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQIISGVEYCHRN 134 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL N+LLD+ VK+ DFGL+ + +GH ++ SP + APE + K Sbjct 135 MVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGH---FLKTSCGSPNYA-APEVISG-K 189 Query 1078 FYYA--SDVWSFGVTLYELL 1095 Y DVWS GV LY LL Sbjct 190 LYAGPEVDVWSCGVILYALL 209 >sp|A2XFF4|OSK3_ORYSI Serine/threonine protein kinase OSK3 OS=Oryza sativa subsp. indica OX=39946 GN=OSK3 PE=3 SV=1 Length=508 Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 71/200 (36%), Positives = 97/200 (49%), Gaps = 16/200 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEH 958 R LG G FGKV + + TG VA+K L + + K+EI ILR H H Sbjct 21 RTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKREIKILRLFIHPH 76 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 II+ + + +VMEY G L DY+ + + + QQI G+ Y H Sbjct 77 IIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQIISGVEYCHRN 134 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL N+LLD+ VK+ DFGL+ + +GH ++ SP + APE + K Sbjct 135 MVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGH---FLKTSCGSPNYA-APEVISG-K 189 Query 1078 FYYA--SDVWSFGVTLYELL 1095 Y DVWS GV LY LL Sbjct 190 LYAGPEVDVWSCGVILYALL 209 >sp|Q62673|PLK1_RAT Serine/threonine-protein kinase PLK1 OS=Rattus norvegicus OX=10116 GN=Plk1 PE=2 SV=2 Length=603 Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 76/269 (28%), Positives = 119/269 (44%), Gaps = 28/269 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEH 958 R LG+G F K C++ ++ T E+ K + P + EI I R+L H+H Sbjct 57 RFLGKGGFAK----CFEISDSDTKEVFPGKIVPKSLLLKPHQKEKMSMEISIHRSLAHQH 112 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 ++ + G ED + +V+E SL + + R ++ + + +QI G YLH Sbjct 113 VVGFHGFFEDSD--FVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRN 170 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRDL N+ L+ D VKIGDFGLA V +E R + +P + APE L + Sbjct 171 QVIHRDLKLGNLFLNEDLEVKIGDFGLATKVE--YEGERKKTLCGTPN-YIAPEVLSKKG 227 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + DVWS G +Y L L+G + + L+ T L + P Sbjct 228 HSFEVDVWSIGCIMYTL----------------LVGKPPFETSCLKETYLRIKKNEYSIP 271 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L++ +T+ + RPT L+ Sbjct 272 KHINPVAASLIQKMLQTDPTARPTIHELL 300 Score = 43.9 bits (102), Expect = 0.008, Method: Compositional matrix adjust. Identities = 46/211 (22%), Positives = 84/211 (40%), Gaps = 16/211 (8%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+ ++H H+ HG +V E L + L + R + +Q+ Sbjct 103 SIHRSLAHQHVVGFHGFFEDSDFVFVVLELCRRRSL-LELHKRRKALTEPEARYYLRQIV 161 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776 YL ++H R++ L L L E +K+ D G+ ER + + Sbjct 162 LGCQYLHRNQVIH-----RDLKLGNLFLNEDLE--VKIGDFGLATKVEYEGERKKTLCGT 214 Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLP 834 ++APE L +S +D W G + + G+ P ++ E + ++ +P Sbjct 215 PNYIAPEVLSKKGHSFE--VDVWSIGCIMYTLLV-GKPPFETSCLKETYLRIKKNEYSIP 271 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + P A+L + L +PT RP+ +L D Sbjct 272 KHINPVAASLIQKMLQTDPTARPTIHELLND 302 >sp|Q8VZJ9|CRCK2_ARATH Calmodulin-binding receptor-like cytoplasmic kinase 2 OS=Arabidopsis thaliana OX=3702 GN=CRCK2 PE=2 SV=1 Length=411 Score = 86.7 bits (213), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 67/207 (32%), Positives = 97/207 (47%), Gaps = 23/207 (11%) Query 903 LGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHEH 958 +G+G FG V + D G+ AVK K + + EI L + H Sbjct 125 IGQGGFGTVYKVKLRD------GKTFAVKRAKKSMHDDRQGADAEFMSEIQTLAQVTHLS 178 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH 1015 ++KY G EK LV+EYV G+LRD+L ++ +A L A + + YLH Sbjct 179 LVKYYGFVVHNDEK--ILVVEYVANGTLRDHLDCKEGKTLDMATRLDIATDVAHAITYLH 236 Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE---GHEYYRVREDGDSPVFWYA 1069 IHRD+ + N+LL + K+ DFG A+ P+ G + + G + + Sbjct 237 MYTQPPIIHRDIKSSNILLTENYRAKVADFGFARLAPDTDSGATHVSTQVKGTAG--YLD 294 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096 PE L Y+ SDV+SFGV L ELLT Sbjct 295 PEYLTTYQLTEKSDVYSFGVLLVELLT 321 Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 52/178 (29%), Positives = 84/178 (47%), Gaps = 15/178 (8%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAWKMV 713 F ++QV+H L +G V E I+V EYV +G L L +E + MA ++ Sbjct 164 FMSEIQTLAQVTHLSLVKYYGFVVHNDEKILVVEYVANGTLRDHLDCKEGKTLDMATRLD 223 Query 714 VAQQLASALSYLENKN---LVHGNVCGRNILLA---RLGLAEGTSPFIKLSDPGVGLGAL 767 +A +A A++YL ++H ++ NILL R +A+ F +L+ P GA Sbjct 224 IATDVAHAITYLHMYTQPPIIHRDIKSSNILLTENYRAKVADF--GFARLA-PDTDSGAT 280 Query 768 SREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ-SRSPSEK 823 +V+ +L PE L L+ D + FG L+E+ G P++ SR E+ Sbjct 281 HVSTQVKGTAGYLDPEYLT--TYQLTEKSDVYSFGVLLVEL-LTGRRPIELSRGQKER 335 >sp|Q9C821|PEK15_ARATH Proline-rich receptor-like protein kinase PERK15 OS=Arabidopsis thaliana OX=3702 GN=PERK15 PE=2 SV=1 Length=509 Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 68/201 (34%), Positives = 101/201 (50%), Gaps = 18/201 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V DGT +VA+K LK+ G R ++ EI + ++H H++ Sbjct 149 LGQGGFGYVHRGVL---VDGT--LVAIKQLKSGSGQGERE-FQAEIQTISRVHHRHLVSL 202 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 G C ++ LV E+VP +L +L R + ++ + A +G+AYLH Sbjct 203 LGYCITGAQR--LLVYEFVPNKTLEFHLHEKERPVMEWSKRMKIALGAAKGLAYLHEDCN 260 Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075 IHRD+ A N+L+D+ K+ DFGLA++ + + R G F Y APE Sbjct 261 PKTIHRDVKAANILIDDSYEAKLADFGLARSSLDTDTHVSTRIMG---TFGYLAPEYASS 317 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 K SDV+S GV L EL+T Sbjct 318 GKLTEKSDVFSIGVVLLELIT 338 Score = 54.3 bits (129), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 51/175 (29%), Positives = 79/175 (45%), Gaps = 19/175 (11%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL-RRERGHVPMAWKMV 713 F +S+V H HL + G C+ G + ++V E+V + L+ L +ER + + +M Sbjct 184 FQAEIQTISRVHHRHLVSLLGYCITGAQRLLVYEFVPNKTLEFHLHEKERPVMEWSKRMK 243 Query 714 VAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 +A A L+YL N +H +V NIL+ S KL+D G+ +L + Sbjct 244 IALGAAKGLAYLHEDCNPKTIHRDVKAANILI-------DDSYEAKLADFGLARSSLDTD 296 Query 771 ERVE-RI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 V RI +LAPE G L+ D + G LLE+ G P+ P Sbjct 297 THVSTRIMGTFGYLAPEYASSG--KLTEKSDVFSIGVVLLEL-ITGRRPVDKSQP 348 >sp|Q9JI10|STK3_MOUSE Serine/threonine-protein kinase 3 OS=Mus musculus OX=10090 GN=Stk3 PE=1 SV=1 Length=497 Score = 87.4 bits (215), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 56/197 (28%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V + + +G++VA+K + + Q +EI I++ ++ Sbjct 30 LEKLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQE---IIKEISIMQQCDSPYV 82 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ + +G+ YLH Sbjct 83 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFM 140 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 141 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 197 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 198 YNCVADIWSLGITSIEM 214 >sp|P51957|NEK4_HUMAN Serine/threonine-protein kinase Nek4 OS=Homo sapiens OX=9606 GN=NEK4 PE=1 SV=2 Length=841 Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 62/200 (31%), Positives = 101/200 (51%), Gaps = 10/200 (5%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +R +G+G +G+V+L + DG ++ L+ + + R +QE +L L H +I Sbjct 9 LRVVGKGSYGEVTLVKH--RRDGKQYVIKKLNLR-NASSRERRAAEQEAQLLSQLKHPNI 65 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLHA 1016 + YK E G+ L +VM + G L L L Q++ + QI + YLH Sbjct 66 VTYKESWEG-GDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHE 124 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +H +HRDL +NV L ++K+GD G+A+ V E H G +P ++ +PE Sbjct 125 KHILHRDLKTQNVFLTRTNIIKVGDLGIAR-VLENHCDMASTLIG-TP-YYMSPELFSNK 181 Query 1077 KFYYASDVWSFGVTLYELLT 1096 + Y SDVW+ G +YE+ T Sbjct 182 PYNYKSDVWALGCCVYEMAT 201 Score = 43.9 bits (102), Expect = 0.010, Method: Compositional matrix adjust. Identities = 52/220 (24%), Positives = 95/220 (43%), Gaps = 20/220 (9%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEYVEHGPLDVWLRRERGHVPMAWK 711 A + A L+SQ+ H ++ + G + ++ V + E G L L+ ++G + + Sbjct 49 AAEQEAQLLSQLKHPNI-VTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQL-LPEN 106 Query 712 MVVA--QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 VV Q+A AL YL K+++H ++ +N+ L R + IK+ D G+ + Sbjct 107 QVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNI-------IKVGDLGIARVLENH 159 Query 770 EERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 + + +++PE + + D W G + E+ A S Sbjct 160 CDMASTLIGTPYYMSPELFSNKPYNYKS--DVWALGCCVYEMATLKHAFNAKDMNSLVYR 217 Query 826 FYQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + + +P P+LA L L+ P +RPS R+ILR Sbjct 218 IIEGKLPPMPRDYSPELAELIRTMLSKRPEERPSVRSILR 257 >sp|Q5R7G9|NUAK2_PONAB NUAK family SNF1-like kinase 2 OS=Pongo abelii OX=9601 GN=NUAK2 PE=2 SV=1 Length=628 Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 62/200 (31%), Positives = 100/200 (50%), Gaps = 15/200 (8%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHE 957 + LG+G +GKV + +G +VA+K+++ D Q ++EI+I+ +L H Sbjct 56 LETLGKGTYGKVK-----KARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHP 110 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHA 1016 HII E+ + + +VMEY G L DY+ R + + F +QI + Y H Sbjct 111 HIIAIHEVFENSSK--IVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQ 168 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL N+LLD + +KI DFGL+ H+ ++ SP++ +PE + Sbjct 169 NRVVHRDLKLENILLDANGNIKIADFGLSNLY---HQGKFLQTFCGSPLY-ASPEIVNGK 224 Query 1077 KFYYAS-DVWSFGVTLYELL 1095 + D WS GV LY L+ Sbjct 225 PYTGPEVDSWSLGVLLYILV 244 Score = 41.2 bits (95), Expect = 0.066, Method: Compositional matrix adjust. Identities = 41/159 (26%), Positives = 65/159 (41%), Gaps = 15/159 (9%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 +MS ++H H+ +H V + ++V EY G L ++ ER + +Q+ S Sbjct 103 IMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYI-SERQQLSEREARHFFRQIVS 161 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---- 776 A+ Y +VH ++ NILL G IK++D GL L + + + Sbjct 162 AVHYCHQNRVVHRDLKLENILLDANG-------NIKIAD--FGLSNLYHQGKFLQTFCGS 212 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 P A + G +D W G LL I G P Sbjct 213 PLYASPEIVNGKPYTGPEVDSWSLG-VLLYILVHGTMPF 250 >sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo sapiens OX=9606 GN=NUAK2 PE=1 SV=1 Length=628 Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 62/200 (31%), Positives = 100/200 (50%), Gaps = 15/200 (8%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHE 957 + LG+G +GKV + +G +VA+K+++ D Q ++EI+I+ +L H Sbjct 56 LETLGKGTYGKVK-----KARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHP 110 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHA 1016 HII E+ + + +VMEY G L DY+ R + + F +QI + Y H Sbjct 111 HIIAIHEVFENSSK--IVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQ 168 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL N+LLD + +KI DFGL+ H+ ++ SP++ +PE + Sbjct 169 NRVVHRDLKLENILLDANGNIKIADFGLSNLY---HQGKFLQTFCGSPLY-ASPEIVNGK 224 Query 1077 KFYYAS-DVWSFGVTLYELL 1095 + D WS GV LY L+ Sbjct 225 PYTGPEVDSWSLGVLLYILV 244 Score = 41.2 bits (95), Expect = 0.064, Method: Compositional matrix adjust. Identities = 41/159 (26%), Positives = 65/159 (41%), Gaps = 15/159 (9%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 +MS ++H H+ +H V + ++V EY G L ++ ER + +Q+ S Sbjct 103 IMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYI-SERQQLSEREARHFFRQIVS 161 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---- 776 A+ Y +VH ++ NILL G IK++D GL L + + + Sbjct 162 AVHYCHQNRVVHRDLKLENILLDANG-------NIKIAD--FGLSNLYHQGKFLQTFCGS 212 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 P A + G +D W G LL I G P Sbjct 213 PLYASPEIVNGKPYTGPEVDSWSLG-VLLYILVHGTMPF 250 >sp|F4JBP3|ATG1B_ARATH Serine/threonine-protein kinase ATG1b OS=Arabidopsis thaliana OX=3702 GN=ATG1B PE=2 SV=1 Length=711 Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 74/235 (31%), Positives = 118/235 (50%), Gaps = 29/235 (12%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHI 959 R +G G F V ++ + G +VA+K + A + + EI ILR + H +I Sbjct 24 RQIGSGSFSVV----WEGRHLVHGTVVAIKEIAMARLNKKLQESLMSEIIILRKINHPNI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018 I++ E G+ + LV+EY G L Y+ +H S+ A F Q+ G+ L + Sbjct 80 IRFIDMIEAPGK--INLVLEYCKGGDLSMYIHKHGSVPEATAKHFMLQLAAGLQVLRDNN 137 Query 1019 YIHRDLAARNVLL---DNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL +N+LL DND +KI DFG A+++ P G + E + APE ++ Sbjct 138 IIHRDLKPQNLLLSTDDNDAALKIADFGFARSLQPRG-----LAETLCGSPLYMAPEIMQ 192 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM--TVLRLTEL 1127 K+ +D+WS G L++L+T ++P T G +Q Q+ ++R TEL Sbjct 193 LQKYDAKADLWSVGAILFQLVT----GRTPFT------GNSQIQLLQNIIRSTEL 237 Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust. Identities = 50/208 (24%), Positives = 89/208 (43%), Gaps = 18/208 (9%) Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 ++ +++H ++ F+ + G N +V EY + G L +++ + G VP A QLA Sbjct 70 ILRKINHPNIIRFIDMIEAPGKIN-LVLEYCKGGDLSMYIHKH-GSVPEATAKHFMLQLA 127 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR---EERVERI 776 + L L + N++H ++ +N+LL+ + +K++D G R E Sbjct 128 AGLQVLRDNNIIHRDLKPQNLLLS----TDDNDAALKIADFGFARSLQPRGLAETLCGSP 183 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836 ++APE + D W GA L ++ G P S + R L P Sbjct 184 LYMAPEIMQ--LQKYDAKADLWSVGAILFQLV-TGRTPFTGNSQIQLLQNIIRSTELHFP 240 Query 837 S-CPQLAT----LTSQCLTYEPTQRPSF 859 + C L+T L + L P +R +F Sbjct 241 ADCRDLSTDCKDLCQKLLRRNPVERLTF 268 >sp|O22808|LYK5_ARATH Protein LYK5 OS=Arabidopsis thaliana OX=3702 GN=LYK5 PE=2 SV=1 Length=664 Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 69/264 (26%), Positives = 122/264 (46%), Gaps = 24/264 (9%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 G+ AVK +K D EI++L+ L H +II+ G C +G LV EY Sbjct 389 GDDAAVKVIKGDVS-------SSEINLLKKLNHSNIIRLSGFCIREGTS--YLVFEYSEN 439 Query 984 GSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLV 1037 GS+ D+L + S+ Q + A+ + E + YLH +IH++L + N+LLD++ Sbjct 440 GSISDWLHSSGKKSLTWKQRVEIARDVAEALDYLHNYITPPHIHKNLESTNILLDSNFRA 499 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT- 1096 KI +FG+A+ + EG ++ + + APE ++ DV++FGV + ELL+ Sbjct 500 KIANFGVARILDEGDLDLQLTRHVEGTQGYLAPEYVENGVITSKLDVFAFGVAVLELLSG 559 Query 1097 ------HCDSSQSPPTKFL--ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148 H + L + + G+ +L E ++ P + + L Sbjct 560 REAVTIHKKKEGEEEVEMLCKVINSVLGGENVREKLKEFMDPSLGNEYPLELAYTMAQLA 619 Query 1149 KNCWETEASFRPTFENLIPILKTV 1172 K+C T+ + RP+ ++ L + Sbjct 620 KSCVATDLNSRPSVTQVLTTLSMI 643 Score = 57.8 bits (138), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 47/167 (28%), Positives = 82/167 (49%), Gaps = 24/167 (14%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK--MVVAQQ 717 +L+ +++H+++ + G C+R + +V EY E+G + WL G + WK + +A+ Sbjct 407 NLLKKLNHSNIIRLSGFCIREGTSYLVFEYSENGSISDWL-HSSGKKSLTWKQRVEIARD 465 Query 718 LASALSYLENKNL---VHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPGVGLGA 766 +A AL YL N +H N+ NILL A G+A ++ D G Sbjct 466 VAEALDYLHNYITPPHIHKNLESTNILLDSNFRAKIANFGVA-------RILDEGDLDLQ 518 Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 L+R + +LAPE + G +++ +D + FG +LE+ EA Sbjct 519 LTRHVEGTQ-GYLAPEYVENGV--ITSKLDVFAFGVAVLELLSGREA 562 >sp|Q9SZD5|LRK59_ARATH L-type lectin-domain containing receptor kinase V.9 OS=Arabidopsis thaliana OX=3702 GN=LECRK59 PE=2 SV=1 Length=669 Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 68/199 (34%), Positives = 99/199 (50%), Gaps = 17/199 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FGKV Y T + +AVK + D R + EI + L H ++++ Sbjct 350 LGKGGFGKV----YKGTLSTSNMDIAVKKVSHDSRQGMRE-FVAEIATIGRLRHPNLVRL 404 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH---A 1016 G C +GE L LV + +P GSL +L P S+ +Q + + G+ YLH Sbjct 405 LGYCRRKGE--LYLVYDCMPKGSLDKFLYHQPEQSLDWSQRFKIIKDVASGLCYLHHQWV 462 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075 Q IHRD+ NVLLD+ K+GDFGLAK G + G F Y +PE + Sbjct 463 QVIIHRDIKPANVLLDDSMNGKLGDFGLAKLCEHGFDPQTSNVAG---TFGYISPELSRT 519 Query 1076 YKFYYASDVWSFGVTLYEL 1094 K +SDV++FG+ + E+ Sbjct 520 GKASTSSDVFAFGILMLEI 538 >sp|Q54MY9|MKCA_DICDI Probable serine/threonine-protein kinase mkcA OS=Dictyostelium discoideum OX=44689 GN=mkcA PE=2 SV=1 Length=860 Score = 88.6 bits (218), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 73/290 (25%), Positives = 129/290 (44%), Gaps = 35/290 (12%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 D PT K+ +G+G FG V Y D + +A+K L P R Sbjct 571 DQICKKPTNEMKKLYTFREKVGKGGFGTV--YLVRNNMDKSKSRIAIKKL-----PHVRK 623 Query 943 GWKQ----EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA 998 K+ EI +L H +II Y E + + ME++ G+L + ++ + Sbjct 624 KEKKFNVKEIRVLEFTNHPNIITYYNSHMLHDE--VWIAMEFMEGGTLAEASNQYPFQES 681 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 + A+++ +G+AYLH +HRDL ++N+++ +K+ DFGL + +G R+R Sbjct 682 NIAYVAREVLQGLAYLHGIQLVHRDLKSQNIMMTTSGEIKLIDFGLCANLSKGE---RIR 738 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 G SP+ W PE +++ + Y D+WS + L EL + + P K + ++G Sbjct 739 MCG-SPI-WMPPEMIQQKQHGYTCDIWSTAICLLELANRNNKLRKNPIKTMFMVG----- 791 Query 1119 MTVLRLTELLERGERLP--RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 G + P P K E + ++ C + + RP+ + L+ Sbjct 792 ----------SEGIKDPFEDPHKWSDEFHDIINKCLQMDPHKRPSAQELL 831 Score = 38.5 bits (88), Expect = 0.48, Method: Compositional matrix adjust. Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 22/160 (14%) Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 VA+++ L+YL LVH ++ +NI++ TS IKL D G+ LS+ ER+ Sbjct 686 VAREVLQGLAYLHGIQLVHRDLKSQNIMMT-------TSGEIKLIDFGL-CANLSKGERI 737 Query 774 ERI---PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 W+ PE + + + D W LLE+ + R K F Sbjct 738 RMCGSPIWMPPEMIQQKQHGYTC--DIWSTAICLLELANRNN---KLRKNPIKTMFMVGS 792 Query 831 HRLPEPS------CPQLATLTSQCLTYEPTQRPSFRTILR 864 + +P + + ++CL +P +RPS + +L+ Sbjct 793 EGIKDPFEDPHKWSDEFHDIINKCLQMDPHKRPSAQELLK 832 >sp|Q6IP06|STK3_XENLA Serine/threonine-protein kinase 3 OS=Xenopus laevis OX=8355 GN=stk3 PE=2 SV=1 Length=493 Score = 87.4 bits (215), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 56/197 (28%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V + + +G++VA+K + + Q +EI I++ ++ Sbjct 29 LEKLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQE---IIKEISIMQQCDSHYV 81 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ + +G+ YLH Sbjct 82 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILRSTLKGLEYLHFM 139 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 140 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVIQEIG 196 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 197 YNCVADIWSLGITSIEM 213 >sp|Q9SCZ4|FERON_ARATH Receptor-like protein kinase FERONIA OS=Arabidopsis thaliana OX=3702 GN=FER PE=1 SV=1 Length=895 Score = 88.2 bits (217), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 77/227 (34%), Positives = 109/227 (48%), Gaps = 26/227 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHE 957 R LG G FGKV Y DG VA+K P G ++ EI++L L H Sbjct 540 RVLGVGGFGKV----YRGEIDGGTTKVAIKR----GNPMSEQGVHEFQTEIEMLSKLRHR 591 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYL 1014 H++ G CE+ E + LV +Y+ G++R++L + S+ Q L G+ YL Sbjct 592 HLVSLIGYCEENCE--MILVYDYMAHGTMREHLYKTQNPSLPWKQRLEICIGAARGLHYL 649 Query 1015 H--AQH-YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWY-A 1069 H A+H IHRD+ N+LLD + K+ DFGL+K P H + G F Y Sbjct 650 HTGAKHTIIHRDVKTTNILLDEKWVAKVSDFGLSKTGPTLDHTHVSTVVKGS---FGYLD 706 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 PE + + SDV+SFGV L+E L C PT E + +A+ Sbjct 707 PEYFRRQQLTEKSDVYSFGVVLFEAL--CARPALNPTLAKEQVSLAE 751 Score = 41.2 bits (95), Expect = 0.073, Method: Compositional matrix adjust. Identities = 47/182 (26%), Positives = 74/182 (41%), Gaps = 9/182 (5%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G G +V +K +P F ++S++ H HL + G C E I+V +Y Sbjct 553 GEIDGGTTKVAIKRGNPMSEQGVHEFQTEIEMLSKLRHRHLVSLIGYCEENCEMILVYDY 612 Query 690 VEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARL 745 + HG + L + + +P ++ + A L YL ++H +V NILL Sbjct 613 MAHGTMREHLYKTQNPSLPWKQRLEICIGAARGLHYLHTGAKHTIIHRDVKTTNILLDEK 672 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATL 804 +A+ S F LS G L V+ +L PE L+ D + FG L Sbjct 673 WVAK-VSDF-GLSKTGPTLDHTHVSTVVKGSFGYLDPEYFR--RQQLTEKSDVYSFGVVL 728 Query 805 LE 806 E Sbjct 729 FE 730 >sp|Q55GV3|PAKC_DICDI Serine/threonine-protein kinase pakC OS=Dictyostelium discoideum OX=44689 GN=pakC PE=1 SV=2 Length=477 Score = 87.0 bits (214), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 63/239 (26%), Positives = 116/239 (49%), Gaps = 22/239 (9%) Query 864 RDLTRLQPHNLADV-----LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918 R + + NL+ + LT++ DPT +K K +GEG G+V + Sbjct 170 RTMEKSNSQNLSALPDESNLTLSDLVTKEDPTKIYKNMTK----IGEGAAGEV----FVA 221 Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978 T+ + VA+K K + + EI I++T +H++I+ Y ++ L + M Sbjct 222 TSSKNNKRVAIK--KIEINNDNAKLLVTEIAIMKTSHHDNIVNYIDSY-IVNDRELWVAM 278 Query 979 EYVPLGSLRDYLPR-HSIGLA--QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035 E++ G L D L +I ++ Q+ ++ + + Y+H+ H IHRD+ + N+LL ++ Sbjct 279 EFMGGGCLTDILEAFDNIKMSEIQIAYVVKETLKALQYIHSLHRIHRDIKSDNILLGSEG 338 Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 VKI DFG A + + + R +W APE ++ + + D+WS G+ + E+ Sbjct 339 SVKIADFGYAAQLTQKQQK---RNTVVGTPYWMAPELIRGHDYGVKVDIWSLGIMMMEM 394 Score = 43.9 bits (102), Expect = 0.010, Method: Compositional matrix adjust. Identities = 61/331 (18%), Positives = 135/331 (41%), Gaps = 40/331 (12%) Query 548 RRCCLPQPGETSNLIIMRGARASPRT--LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605 ++ L +P E +++ + R ++ NLS L D+ +T + + T +Y+ Sbjct 150 KQEVLDKPSEWLSVLEFQAGRTMEKSNSQNLSALP----DESNLTLSDLVTKEDPTKIYK 205 Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV 665 ++ G+ G++ V + + RV +K ++ ++ + L E A + + Sbjct 206 NMTKI---GEGAAGEV-----FVATSSKNNK-RVAIKKIEINNDNAKLLVTEIAIMKTSH 256 Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHG----PLDVWLRRERGHVPMAWKMVVAQQLASA 721 + ++ V E + E++ G L+ + + + +A+ V ++ A Sbjct 257 HDNIVNYIDSYIVNDRELWVAMEFMGGGCLTDILEAFDNIKMSEIQIAY---VVKETLKA 313 Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---- 777 L Y+ + + +H ++ NILL +EG+ +K++D G ++++ + Sbjct 314 LQYIHSLHRIHRDIKSDNILLG----SEGS---VKIADFGYAAQLTQKQQKRNTVVGTPY 366 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS 837 W+APE + G + +D W G ++E+ +GE P P + P Sbjct 367 WMAPELIRG--HDYGVKVDIWSLGIMMMEMA-EGEPPYMDFPPLRALFLITTKGIPPLKE 423 Query 838 CPQLAT----LTSQCLTYEPTQRPSFRTILR 864 + + S+CL RP +L+ Sbjct 424 TTKWSKTFQDFFSKCLDINVANRPDATDLLK 454 >sp|Q8H1G6|PTI11_ARATH PTI1-like tyrosine-protein kinase 1 OS=Arabidopsis thaliana OX=3702 GN=PTI11 PE=1 SV=1 Length=361 Score = 85.9 bits (211), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 80/285 (28%), Positives = 127/285 (45%), Gaps = 28/285 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG--WKQEIDILRTLYHEHII 960 +GEG +G+V Y NDG VAV K D P+ + + ++ ++ L HE++I Sbjct 74 IGEGSYGRVY---YATLNDG----VAVALKKLDVAPEAETDTEFLSQVSMVSRLKHENLI 126 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQLLLFAQQICEG 1010 + G C D + L E+ +GSL D L P ++ + A + G Sbjct 127 QLLGFCVDGNLRVL--AYEFATMGSLHDILHGRKGVQGAQPGPTLDWITRVKIAVEAARG 184 Query 1011 MAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH + IHRD+ + NVLL D KI DF L+ P+ R+ F Sbjct 185 LEYLHEKSQPPVIHRDIRSSNVLLFEDYKAKIADFNLSNQAPDNAA--RLHSTRVLGTFG 242 Query 1068 Y-APECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 Y APE + SDV+SFGV L ELLT + P L+ A +++ ++ Sbjct 243 YHAPEYAMTGQLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRLSEDKVK 302 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + ++ + P K ++ + C + EA FRP ++ L+ Sbjct 303 QCIDPKLKADYPPKAVAKLAAVAALCVQYEAEFRPNMSIVVKALQ 347 Score = 40.4 bits (93), Expect = 0.081, Method: Compositional matrix adjust. Identities = 65/262 (25%), Positives = 106/262 (40%), Gaps = 36/262 (14%) Query 639 VVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-D 696 V LK LD + + F S++S++ H +L + G CV G ++ E+ G L D Sbjct 93 VALKKLDVAPEAETDTEFLSQVSMVSRLKHENLIQLLGFCVDGNLRVLAYEFATMGSLHD 152 Query 697 VWLRRE--RGHVP---MAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLG 746 + R+ +G P + W ++ +A + A L YL K+ ++H ++ N+LL Sbjct 153 ILHGRKGVQGAQPGPTLDWITRVKIAVEAARGLEYLHEKSQPPVIHRDIRSSNVLLFEDY 212 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 A+ LS+ A RV + APE G L+ D + FG LL Sbjct 213 KAKIAD--FNLSNQAPDNAARLHSTRVLGTFGYHAPEYAMTG--QLTQKSDVYSFGVVLL 268 Query 806 EICFDGEAPLQSRSPSEKEHFYQ-RQHRLPEPSCPQ-----------------LATLTSQ 847 E+ G P+ P ++ RL E Q LA + + Sbjct 269 EL-LTGRKPVDHTMPRGQQSLVTWATPRLSEDKVKQCIDPKLKADYPPKAVAKLAAVAAL 327 Query 848 CLTYEPTQRPSFRTILRDLTRL 869 C+ YE RP+ +++ L L Sbjct 328 CVQYEAEFRPNMSIVVKALQPL 349 >sp|Q60806|PLK3_MOUSE Serine/threonine-protein kinase PLK3 OS=Mus musculus OX=10090 GN=Plk3 PE=1 SV=2 Length=631 Score = 87.8 bits (216), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 67/220 (30%), Positives = 105/220 (48%), Gaps = 17/220 (8%) Query 882 PDSPA---SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--C 936 PD P +DP R K R LG+G F + CY+ T+ +G AVK + Sbjct 47 PDPPGRLITDP--LSGRTYTKGRLLGKGGFAR----CYEATDTESGIAYAVKVIPQSRVA 100 Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSI 995 P R EI++ R L H HI+++ ED ++ + +E SL + RH++ Sbjct 101 KPHQREKILNEIELHRDLQHRHIVRFSHHFEDA--DNIYIFLELCSRKSLAHIWKARHTL 158 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 ++ + +QI G+ YLH + +HRDL N + ++ +K+GDFGLA + + Sbjct 159 LEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAARLEPPEQ-- 216 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 R + +P + APE L +DVWS G +Y LL Sbjct 217 RKKTICGTPNY-VAPEVLLRQGHGPEADVWSLGCVMYTLL 255 >sp|O49339|PTI12_ARATH PTI1-like tyrosine-protein kinase 2 OS=Arabidopsis thaliana OX=3702 GN=PTI12 PE=1 SV=1 Length=366 Score = 85.9 bits (211), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 76/283 (27%), Positives = 127/283 (45%), Gaps = 24/283 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG +G+V Y NDG VA+K L + + + ++ ++ L HE++I+ Sbjct 77 IGEGSYGRV---YYATLNDGKA--VALKKLDVAPEAETNTEFLNQVSMVSRLKHENLIQL 131 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQLLLFAQQICEGMA 1012 G C D+ + L E+ +GSL D L P ++ + A + G+ Sbjct 132 VGYCVDENLRVL--AYEFATMGSLHDILHGRKGVQGAQPGPTLDWLTRVKIAVEAARGLE 189 Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068 YLH + IHRD+ + NVLL D K+ DF L+ P+ R+ F Y Sbjct 190 YLHEKVQPPVIHRDIRSSNVLLFEDYQAKVADFNLSNQAPDNAA--RLHSTRVLGTFGYH 247 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + SDV+SFGV L ELLT + P L+ A +++ ++ + Sbjct 248 APEYAMTGQLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRLSEDKVKQC 307 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 ++ + P K ++ + C + E+ FRP ++ L+ Sbjct 308 VDPKLKGEYPPKSVAKLAAVAALCVQYESEFRPNMSIVVKALQ 350 Score = 37.0 bits (84), Expect = 1.0, Method: Compositional matrix adjust. Identities = 62/262 (24%), Positives = 105/262 (40%), Gaps = 36/262 (14%) Query 639 VVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-D 696 V LK LD + + F S++S++ H +L + G CV ++ E+ G L D Sbjct 96 VALKKLDVAPEAETNTEFLNQVSMVSRLKHENLIQLVGYCVDENLRVLAYEFATMGSLHD 155 Query 697 VWLRRE--RGHVP---MAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLG 746 + R+ +G P + W ++ +A + A L YL K ++H ++ N+LL Sbjct 156 ILHGRKGVQGAQPGPTLDWLTRVKIAVEAARGLEYLHEKVQPPVIHRDIRSSNVLLFEDY 215 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 A+ LS+ A RV + APE G L+ D + FG LL Sbjct 216 QAKVAD--FNLSNQAPDNAARLHSTRVLGTFGYHAPEYAMTG--QLTQKSDVYSFGVVLL 271 Query 806 EICFDGEAPLQSRSPSEKEHFY------------------QRQHRLPEPSCPQLATLTSQ 847 E+ G P+ P ++ + + P S +LA + + Sbjct 272 EL-LTGRKPVDHTMPRGQQSLVTWATPRLSEDKVKQCVDPKLKGEYPPKSVAKLAAVAAL 330 Query 848 CLTYEPTQRPSFRTILRDLTRL 869 C+ YE RP+ +++ L L Sbjct 331 CVQYESEFRPNMSIVVKALQPL 352 >sp|Q751E8|PHO85_EREGS Negative regulator of the PHO system OS=Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=PHO85 PE=3 SV=2 Length=301 Score = 84.7 bits (208), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 63/209 (30%), Positives = 102/209 (49%), Gaps = 22/209 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 K++ LG G + V Y N TG VA+K +K D S +EI +++ L H Sbjct 7 FKQLERLGNGTYATV----YKGLNKTTGLYVALKEVKLDSEEGTPSTAIREISLMKELKH 62 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--------PRHSIGLAQLLLFAQQIC 1008 E+I++ E L LV E++ L+ ++ PR + L+ + F Q+ Sbjct 63 ENIVRLYDVI--HTENKLTLVFEFMD-NDLKKFMDSRLDREMPR-GLELSLVKYFQWQLL 118 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +G+A+ H +HRDL +N+L++N +K+GDFGLA+A + + WY Sbjct 119 QGVAFCHENRILHRDLKPQNLLINNKGQLKLGDFGLARAFGIPVNTF----SSEVVTLWY 174 Query 1069 -APECLKEYKFYYAS-DVWSFGVTLYELL 1095 AP+ L + Y S D+WS G L E++ Sbjct 175 RAPDVLMGSRTYCTSIDIWSCGCILAEMI 203 >sp|Q9FM85|PBL16_ARATH Probable serine/threonine-protein kinase PBL16 OS=Arabidopsis thaliana OX=3702 GN=PBL16 PE=1 SV=1 Length=408 Score = 86.3 bits (212), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 89/272 (33%), Positives = 124/272 (46%), Gaps = 25/272 (9%) Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI-------RDLGEGHFGKVSLYC 915 ++++ +L P N +V + DS A+ F LK I R LG G FG V Sbjct 36 IKEVQKL-PSNPKEVEDLRRDSAANPLIAFTYEELKNITSNFRQDRVLGGGGFGSV-YKG 93 Query 916 YDPTNDGTGEM-----VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG-CCEDQ 969 + + G E+ VAVK D Q W E+ L L H +++K G CCED Sbjct 94 FIKEDLGDQEVPEPLPVAVKVHDGDNSFQGHREWLAEVIFLGQLSHPNLVKLIGYCCEDN 153 Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSI---GLAQLLLFAQQICEGMAYLH--AQHYIHRDL 1024 L+ EY+ GS+ + L + A + A +G+A+LH + I+RD Sbjct 154 HR---VLIYEYMARGSVENNLFSRVLLPLSWAIRMKIAFGAAKGLAFLHEAKKPVIYRDF 210 Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084 N+LLD D K+ DFGLAK P G + + V + APE + SDV Sbjct 211 KTSNILLDMDYNAKLSDFGLAKDGPVGDKSH-VSTRIMGTYGYAAPEYIMTGHLTPGSDV 269 Query 1085 WSFGVTLYELLTHCDS-SQSPPTKFLELIGIA 1115 +SFGV L ELLT S +S PT+ LI A Sbjct 270 YSFGVVLLELLTGRKSLDKSRPTREQNLIDWA 301 Score = 50.4 bits (119), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 66/268 (25%), Positives = 110/268 (41%), Gaps = 31/268 (12%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQL 718 + Q+SH +L + G C +++ EY+ G ++ L R +P++W +M +A Sbjct 133 FLGQLSHPNLVKLIGYCCEDNHRVLIYEYMARGSVENNL-FSRVLLPLSWAIRMKIAFGA 191 Query 719 ASALSYLE--NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI 776 A L++L K +++ + NILL + S F D VG + + Sbjct 192 AKGLAFLHEAKKPVIYRDFKTSNILL-DMDYNAKLSDFGLAKDGPVGDKSHVSTRIMGTY 250 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--------Q 828 + APE + G L+ D + FG LLE+ G L P+ +++ + Sbjct 251 GYAAPEYIMTG--HLTPGSDVYSFGVVLLEL-LTGRKSLDKSRPTREQNLIDWALPLLKE 307 Query 829 RQHRL----PEPSCP-------QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 ++ L P+ +C + A L CL P RP R I+ L LQ + Sbjct 308 KKKVLNIVDPKMNCEYPVKAVQKAAMLAYHCLNRNPKARPLMRDIVDSLEPLQATE-EEA 366 Query 878 LTVNPDSPASDPTV--FHKRYLKKIRDL 903 L V P A + K LKK+ +L Sbjct 367 LLVPPVQKAVITIIDEMPKNGLKKVEEL 394 >sp|Q5AG71|HSL1_CANAL Serine/threonine-protein kinase HSL1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=HSL1 PE=1 SV=2 Length=1462 Score = 88.6 bits (218), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 67/214 (31%), Positives = 109/214 (51%), Gaps = 29/214 (14%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-----KADCGPQHRS----------GWK 945 R LG G G+V L N TG++ AVK + K P+++ G + Sbjct 69 RTLGRGSTGRVRL----AKNTTTGQLAAVKIVPKSNFKKLENPKYKRSKEDATRLPYGIE 124 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFA 1004 +EI I++ + H +I+ E++ + L L++EY+ G L DYL R + + + + Sbjct 125 REIIIMKLISHPNIMGLYDVWENKND--LYLILEYIEGGELFDYLIKRGKLQEYEAINYF 182 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK-AVPEGHEYYRVREDGDS 1063 +QI G+ YLH + HRDL N+LLD ++ +KI DFG+A V E ++ E Sbjct 183 KQIINGINYLHQFNICHRDLKPENLLLDFNKNIKIADFGMAALEVKE-----KLLETSCG 237 Query 1064 PVFWYAPECLKEYKFYYA-SDVWSFGVTLYELLT 1096 + +PE + ++ A SD+WS G+ L+ LLT Sbjct 238 SPHYASPEIVAGKNYHGAPSDIWSCGIILFALLT 271 Score = 36.2 bits (82), Expect = 2.7, Method: Compositional matrix adjust. Identities = 38/162 (23%), Positives = 72/162 (44%), Gaps = 21/162 (13%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 +M +SH ++ ++ V + ++ EY+E G L +L + RG + + +Q+ + Sbjct 129 IMKLISHPNIMGLYDVWENKNDLYLILEYIEGGELFDYLIK-RGKLQEYEAINYFKQIIN 187 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP--- 777 ++YL N+ H ++ N+LL + IK++D G+ AL +E++ Sbjct 188 GINYLHQFNICHRDLKPENLLL-------DFNKNIKIAD--FGMAALEVKEKLLETSCGS 238 Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGE 812 + +PE + G N D W G L + FD E Sbjct 239 PHYASPEIV-AGKNYHGAPSDIWSCGIILFALLTGHLPFDDE 279 >sp|Q07832|PLK1_MOUSE Serine/threonine-protein kinase PLK1 OS=Mus musculus OX=10090 GN=Plk1 PE=1 SV=2 Length=603 Score = 87.4 bits (215), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 76/269 (28%), Positives = 119/269 (44%), Gaps = 28/269 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEH 958 R LG+G F K C++ ++ T E+ A K + P + EI I R+L H+H Sbjct 57 RFLGKGGFAK----CFEISDADTKEVFAGKIVPKSLLLKPHQKEKMSMEISIHRSLAHQH 112 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 ++ + ED + +V+E SL + + R ++ + + +QI G YLH Sbjct 113 VVGFHDFFEDSD--FVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRN 170 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRDL N+ L+ D VKIGDFGLA V +E R + +P + APE L + Sbjct 171 QVIHRDLKLGNLFLNEDLEVKIGDFGLATKVE--YEGERKKTLCGTPN-YIAPEVLSKKG 227 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + DVWS G +Y L L+G + + L+ T L + P Sbjct 228 HSFEVDVWSIGCIMYTL----------------LVGKPPFETSCLKETYLRIKKNEYSIP 271 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L++ +T+ + RPT L+ Sbjct 272 KHINPVAASLIQKMLQTDPTARPTIHELL 300 Score = 41.6 bits (96), Expect = 0.055, Method: Compositional matrix adjust. Identities = 36/155 (23%), Positives = 66/155 (43%), Gaps = 15/155 (10%) Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER 775 +Q+ YL ++H R++ L L L E +K+ D G+ ER + Sbjct 158 RQIVLGCQYLHRNQVIH-----RDLKLGNLFLNEDLE--VKIGDFGLATKVEYEGERKKT 210 Query 776 I----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQ 830 + ++APE L +S +D W G + + G+ P ++ E + + Sbjct 211 LCGTPNYIAPEVLSKKGHSFE--VDVWSIGCIMYTLLV-GKPPFETSCLKETYLRIKKNE 267 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + +P+ P A+L + L +PT RP+ +L D Sbjct 268 YSIPKHINPVAASLIQKMLQTDPTARPTIHELLND 302 >sp|P51958|CDK1_CARAU Cyclin-dependent kinase 1 OS=Carassius auratus OX=7957 GN=cdk1 PE=1 SV=1 Length=302 Score = 84.7 bits (208), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 70/235 (30%), Positives = 110/235 (47%), Gaps = 27/235 (11%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957 KI +GEG +G V Y N TG++VA+K ++ + + S +EI +L+ L H Sbjct 6 KIEKIGEGTYGVV----YKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHP 61 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL------LFAQQICEGM 1011 ++++ E L LV E++ + L+ YL SI Q + + QI EG+ Sbjct 62 NVVRLLDVL--MQESKLYLVFEFLSM-DLKKYL--DSIPSGQFMDPMLVKSYLYQILEGI 116 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-AP 1070 + H + +HRDL +N+L+DN ++K+ DFGLA+A Y + WY AP Sbjct 117 LFCHCRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVPVRVYT----HEVVTLWYRAP 172 Query 1071 EC-LKEYKFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQM 1119 E L ++ DVWS G EL T H DS + +G ++ Sbjct 173 EVLLGASRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNEV 227 >sp|Q9M9E0|LRKS1_ARATH L-type lectin-domain containing receptor kinase S.1 OS=Arabidopsis thaliana OX=3702 GN=LECRKS1 PE=1 SV=1 Length=656 Score = 87.8 bits (216), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 67/202 (33%), Positives = 101/202 (50%), Gaps = 16/202 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LG G FGKV Y E +AVK + D R + EI + L H++++ Sbjct 365 RLLGSGGFGKV----YRGILSNNSE-IAVKCVNHDSKQGLRE-FMAEISSMGRLQHKNLV 418 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH-- 1015 + +G C + E L LV +Y+P GSL ++ P+ + + + EG+ YLH Sbjct 419 QMRGWCRRKNE--LMLVYDYMPNGSLNQWIFDNPKEPMPWRRRRQVINDVAEGLNYLHHG 476 Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 Q IHRD+ + N+LLD++ ++GDFGLAK G R G + + APE Sbjct 477 WDQVVIHRDIKSSNILLDSEMRGRLGDFGLAKLYEHGGAPNTTRVVG--TLGYLAPELAS 534 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 ASDV+SFGV + E+++ Sbjct 535 ASAPTEASDVYSFGVVVLEVVS 556 Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 47/168 (28%), Positives = 82/168 (49%), Gaps = 13/168 (8%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F S M ++ H +L + G C R E ++V +Y+ +G L+ W+ + PM W + Sbjct 402 FMAEISSMGRLQHKNLVQMRGWCRRKNELMLVYDYMPNGSLNQWI-FDNPKEPMPWRRRR 460 Query 713 VVAQQLASALSYLE---NKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALS 768 V +A L+YL ++ ++H ++ NILL + + G KL + G GA + Sbjct 461 QVINDVAEGLNYLHHGWDQVVIHRDIKSSNILLDSEMRGRLGDFGLAKLYEHG---GAPN 517 Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 V + +LAPE A++ + A D + FG +LE+ G P++ Sbjct 518 TTRVVGTLGYLAPEL--ASASAPTEASDVYSFGVVVLEVV-SGRRPIE 562 >sp|Q7ZUQ3|STK3_DANRE Serine/threonine-protein kinase 3 OS=Danio rerio OX=7955 GN=stk3 PE=2 SV=1 Length=492 Score = 87.0 bits (214), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 56/197 (28%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V + + +G++VA+K + + Q +EI I++ ++ Sbjct 29 LEKLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQE---IIKEISIMQQCDSPYV 81 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D L ++ ++ + +G+ YLH Sbjct 82 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLKSTLKGLEYLHFM 139 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 140 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK---RNTVIGTPFWMAPEVIQEIG 196 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 197 YNCVADIWSLGITSIEM 213 >sp|C0LGW2|PAM74_ARATH Probable LRR receptor-like serine/threonine-protein kinase PAM74 OS=Arabidopsis thaliana OX=3702 GN=PAM74 PE=1 SV=1 Length=884 Score = 88.2 bits (217), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 57/181 (31%), Positives = 93/181 (51%), Gaps = 11/181 (6%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 E VAVK L + Q +K E+D+L ++H +++ G C+++ L L+ E++P Sbjct 601 SEQVAVKVL-SQSSSQGYKHFKAEVDLLLRVHHTNLVSLVGYCDERDH--LALIYEFLPK 657 Query 984 GSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRL 1036 G LR +L S I L A + G+ YLH+ +HRD+ N+LLD Sbjct 658 GDLRQHLSGKSGGSFINWGNRLRIALEAALGLEYLHSGCTPPIVHRDIKTTNILLDEQLK 717 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 K+ DFGL+++ P G E + +P + PE + + SDV+SFG+ L E++T Sbjct 718 AKLADFGLSRSFPIGGETHISTVVAGTPGY-LDPEYYQTTRLGEKSDVYSFGIVLLEIIT 776 Query 1097 H 1097 + Sbjct 777 N 777 Score = 40.8 bits (94), Expect = 0.085, Method: Compositional matrix adjust. Identities = 57/203 (28%), Positives = 82/203 (40%), Gaps = 21/203 (10%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G G E +V +KVL S F L+ +V HT+L + G C ++ E+ Sbjct 596 GTINGSE-QVAVKVLSQSSSQGYKHFKAEVDLLLRVHHTNLVSLVGYCDERDHLALIYEF 654 Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744 + G L L + G + W ++ +A + A L YL + +VH ++ NILL Sbjct 655 LPKGDLRQHLSGKSGGSFINWGNRLRIALEAALGLEYLHSGCTPPIVHRDIKTTNILLDE 714 Query 745 LGLAEGTSPFIKLSDPGVGL-----GALSREERVERIP-WLAPECLPGGANSLSTAMDKW 798 A KL+D G+ G V P +L PE L D + Sbjct 715 QLKA-------KLADFGLSRSFPIGGETHISTVVAGTPGYLDPEYYQ--TTRLGEKSDVY 765 Query 799 GFGATLLEICFDGEAPLQSRSPS 821 FG LLEI + QSRS S Sbjct 766 SFGIVLLEIITNQPVIDQSRSKS 788 >sp|Q54EY4|DST3_DICDI Serine/threonine-protein kinase dst3 OS=Dictyostelium discoideum OX=44689 GN=dst3 PE=3 SV=1 Length=562 Score = 87.0 bits (214), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 61/200 (31%), Positives = 101/200 (51%), Gaps = 15/200 (8%) Query 903 LGEGHFGKVS----LYCYDPTNDGTGEMVAVKALKADCGPQHRS-GWKQEIDILR-TLYH 956 +G G FG V + D ++G ++A K ++ + + +EIDIL+ ++ Sbjct 29 VGSGSFGTVCACRWMKKKDRESNG-NRLIACKFVEVNADDVETNLNLVKEIDILKESMDC 87 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYL 1014 +I++YKGC L +VMEY GSL D + L + + + +G+ YL Sbjct 88 PYIVEYKGCYLKSS--MLLIVMEYCKGGSLLDIIELCGKRLIEEEIAAVCAGVVKGLVYL 145 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H++ HRD+ A NVLLD + L K+ DFG++ +G + V SP +W APE + Sbjct 146 HSKRTTHRDIKAGNVLLDEEGLPKLADFGVSTIAEQGQKMNTVI---GSP-YWMAPEIIM 201 Query 1075 EYKFYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 202 GQGYDQKADIWSLGITAIEI 221 Score = 43.5 bits (101), Expect = 0.011, Method: Compositional matrix adjust. Identities = 52/197 (26%), Positives = 80/197 (41%), Gaps = 37/197 (19%) Query 684 IMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLASA-------LSYLENKNLVHGNV 735 ++V EY + G L D+ + + K ++ +++A+ L YL +K H ++ Sbjct 104 LIVMEYCKGGSLLDI--------IELCGKRLIEEEIAAVCAGVVKGLVYLHSKRTTHRDI 155 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---WLAPECLPGGANSLS 792 N+LL GL KL+D GV A ++ I W+APE + G Sbjct 156 KAGNVLLDEEGLP-------KLADFGVSTIAEQGQKMNTVIGSPYWMAPEIIMGQG--YD 206 Query 793 TAMDKWGFGATLLEIC------FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTS 846 D W G T +EI FD P SR H ++P P+ Sbjct 207 QKADIWSLGITAIEIAELVPPRFD--VP-PSRVIFTIPHQPPPSLKIPSDWSPEFNDFVK 263 Query 847 QCLTYEPTQRPSFRTIL 863 QCL+ P RPS + +L Sbjct 264 QCLSMNPALRPSAQQLL 280 >sp|Q9LFT8|CDKC1_ARATH Cyclin-dependent kinase C-1 OS=Arabidopsis thaliana OX=3702 GN=CDKC-1 PE=1 SV=1 Length=505 Score = 87.0 bits (214), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 67/221 (30%), Positives = 105/221 (48%), Gaps = 33/221 (15%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILR 952 +K+ +GEG +G+V Y TGE+VA+K ++ D R G+ +EI IL+ Sbjct 26 FEKLEQIGEGTYGQV----YMAKEIKTGEIVALKKIRMD---NEREGFPITAIREIKILK 78 Query 953 TLYHEHIIKYKGCC-------EDQGEKS-------LQLVMEYVP--LGSLRDYLPRHSIG 996 L+HE++I+ K +DQG+ + +V EY+ L L D P Sbjct 79 KLHHENVIQLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLAD-RPGLRFT 137 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 + Q+ + +Q+ G+ Y H +HRD+ N+L+DN+ +K+ DFGLA++ H Sbjct 138 VPQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGNL 197 Query 1057 VREDGDSPVFWYAPE--CLKEYKFYYASDVWSFGVTLYELL 1095 WY P L K+ A D+WS G ELL Sbjct 198 TNR---VITLWYRPPELLLGATKYGPAIDMWSVGCIFAELL 235 >sp|U4PR86|MELK_CAEEL Maternal embryonic leucine zipper kinase OS=Caenorhabditis elegans OX=6239 GN=pig-1 PE=1 SV=1 Length=706 Score = 87.4 bits (215), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 67/199 (34%), Positives = 101/199 (51%), Gaps = 12/199 (6%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +LG G FGKV L + TN + VA+K + + E+D LR L H++I + Sbjct 16 ELGSGGFGKVRLATHLLTN----QKVAIKIIDKKQLGHDLPRVQTEMDALRNLSHQNICR 71 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020 E E +VMEY G + DY+ R + ++ F +Q+ +A++H+Q Y Sbjct 72 LYHYIET--EDKFFIVMEYCSGGEMFDYIVRKERLEESEARHFFRQLVSAIAFVHSQGYA 129 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH-EYYRVREDGDSPVFWYAPECLK--EYK 1077 HRDL N+LL D +K+ DFGL +G + + + SP + APE ++ +YK Sbjct 130 HRDLKPENLLLTEDLHLKLIDFGLCAKTEKGRIDKHNLDTCCGSPAY-AAPELIQGLQYK 188 Query 1078 FYYASDVWSFGVTLYELLT 1096 A DVWS G+ LY LL Sbjct 189 GNEA-DVWSMGILLYTLLV 206 >sp|C0LGL4|Y2289_ARATH Probable LRR receptor-like serine/threonine-protein kinase At2g28960 OS=Arabidopsis thaliana OX=3702 GN=At2g28960 PE=1 SV=1 Length=880 Score = 87.8 bits (216), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 64/203 (32%), Positives = 103/203 (51%), Gaps = 16/203 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LGEG FG V Y +GT + +AVK L + Q +K E+++L ++H +++ Sbjct 577 RVLGEGGFGVV----YHGILNGT-QPIAVKLL-SQSSVQGYKEFKAEVELLLRVHHVNLV 630 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLHA 1016 G C++ E +L L+ EY P G L+ +L G + L + +G+ YLH Sbjct 631 SLVGYCDE--ESNLALLYEYAPNGDLKQHLSGERGGSPLKWSSRLKIVVETAQGLEYLHT 688 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +HRD+ N+LLD K+ DFGL+++ P G E + +P + PE Sbjct 689 GCKPPMVHRDVKTTNILLDEHFQAKLADFGLSRSFPVGGETHVSTAVAGTPGYL-DPEYY 747 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 + + SDV+SFG+ L E++T Sbjct 748 RTNRLNEKSDVYSFGIVLLEIIT 770 Score = 47.4 bits (111), Expect = 0.001, Method: Compositional matrix adjust. Identities = 56/199 (28%), Positives = 79/199 (40%), Gaps = 23/199 (12%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 + +K+L S F L+ +V H +L + G C ++ EY +G L Sbjct 598 IAVKLLSQSSVQGYKEFKAEVELLLRVHHVNLVSLVGYCDEESNLALLYEYAPNGDLKQH 657 Query 699 LRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSP 753 L ERG P+ W ++ + + A L YL +VH +V NILL A Sbjct 658 LSGERGGSPLKWSSRLKIVVETAQGLEYLHTGCKPPMVHRDVKTTNILLDEHFQA----- 712 Query 754 FIKLSDPGVGL-----GALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 KL+D G+ G V P +L PE N L+ D + FG LLEI Sbjct 713 --KLADFGLSRSFPVGGETHVSTAVAGTPGYLDPEYY--RTNRLNEKSDVYSFGIVLLEI 768 Query 808 CFDGEAPLQSRSPSEKEHF 826 Q+R EK H Sbjct 769 ITSRPVIQQTR---EKPHI 784 >sp|Q84SN3|CDKF3_ORYSJ Cyclin-dependent kinase F-3 OS=Oryza sativa subsp. japonica OX=39947 GN=CDKF-3 PE=2 SV=1 Length=433 Score = 86.3 bits (212), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 71/210 (34%), Positives = 101/210 (48%), Gaps = 24/210 (11%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 +RY K IR++G+G G V + N T E+VAVK +K +E+ L+ Sbjct 2 ERY-KVIREIGDGTCGNV----FRAYNTETNEIVAVKKMKRKFFQWEECISLREVKALQK 56 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGM 1011 L H +I+K K + E L + E + +L D + ++ + F QI +G+ Sbjct 57 LNHPNIVKLKEVTMENHE--LFFIFENMEC-NLYDVIRERQAAFSEEEIRNFMVQILQGL 113 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV---PEGHEYYRVREDGDSPVFWY 1068 AY+H Y HRDL N+L+ D VKI DFGLA+ V P +Y R WY Sbjct 114 AYMHNNGYFHRDLKPENLLV-TDGTVKIADFGLAREVSSSPPYTDYVSTR--------WY 164 Query 1069 -APECLKEYKFYY-ASDVWSFGVTLYELLT 1096 APE L + Y A D+W+ G L EL T Sbjct 165 RAPEVLLQSSAYTPAIDMWAVGAILAELFT 194 >sp|Q9FIZ3|GSO2_ARATH LRR receptor-like serine/threonine-protein kinase GSO2 OS=Arabidopsis thaliana OX=3702 GN=GSO2 PE=1 SV=2 Length=1252 Score = 87.8 bits (216), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 65/220 (30%), Positives = 103/220 (47%), Gaps = 16/220 (7%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 D + YL + +G G GKV Y + N GE +AVK + + +E Sbjct 939 DDIMEATHYLNEEFMIGSGGSGKV--YKAELKN---GETIAVKKILWKDDLMSNKSFNRE 993 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSIGLAQL 1000 + L T+ H H++K G C + + L+ EY+ GS+ D+L + +G Sbjct 994 VKTLGTIRHRHLVKLMGYCSSKADGLNLLIYEYMANGSVWDWLHANENTKKKEVLGWETR 1053 Query 1001 LLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 L A + +G+ YLH +HRD+ + NVLLD++ +GDFGLAK + ++ Sbjct 1054 LKIALGLAQGVEYLHYDCVPPIVHRDIKSSNVLLDSNIEAHLGDFGLAKILTGNYDTNTE 1113 Query 1058 REDGDSPVFWY-APECLKEYKFYYASDVWSFGVTLYELLT 1096 + + Y APE K SDV+S G+ L E++T Sbjct 1114 SNTMFAGSYGYIAPEYAYSLKATEKSDVYSMGIVLMEIVT 1153 >sp|Q13188|STK3_HUMAN Serine/threonine-protein kinase 3 OS=Homo sapiens OX=9606 GN=STK3 PE=1 SV=2 Length=491 Score = 86.7 bits (213), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 56/197 (28%), Positives = 97/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V + + +G++VA+K + + Q +EI I++ ++ Sbjct 30 LEKLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQE---IIKEISIMQQCDSPYV 82 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQ 1017 +KY G + L +VMEY GS+ D + + L + + + +G+ YLH Sbjct 83 VKYYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFM 140 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E Sbjct 141 RKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVIQEIG 197 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+WS G+T E+ Sbjct 198 YNCVADIWSLGITSIEM 214 >sp|P83104|M3K7L_DROME Putative mitogen-activated protein kinase kinase kinase 7-like OS=Drosophila melanogaster OX=7227 GN=Takl1 PE=2 SV=1 Length=393 Score = 85.5 bits (210), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 76/254 (30%), Positives = 125/254 (49%), Gaps = 33/254 (13%) Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGL 997 + ++EI L + HE++I+ G + G+K L+MEY+ GSL +YL + + Sbjct 48 KKNAEREITHLSEIDHENVIRVIGRASN-GKKDY-LLMEYLEEGSLHNYLYGDDKWEYTV 105 Query 998 AQLLLFAQQICEGMAYLHA--QHYIHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEY 1054 Q + +A Q + +AYLH+ + +HRD+ +N+LL N +KI DFGLA + Sbjct 106 EQAVRWALQCAKALAYLHSLDRPIVHRDIKPQNMLLYNQHEDLKICDFGLATDMSNN--- 162 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + D + + APE +K K+ DV+SFG+ L+EL+T + P LE Sbjct 163 ---KTDMQGTLRYMAPEAIKHLKYTAKCDVYSFGIMLWELMT-----RQLPYSHLE---N 211 Query 1115 AQGQMTVLRLTELLERGERLP----RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 Q +++ + GE+LP R D CP + LM+ C + RP+ + I K Sbjct 212 PNSQYAIMK---AISSGEKLPMEAVRSD-CPEGIKQLMECCMDINPEKRPSMKE---IEK 264 Query 1171 TVHEKYQGQAPSVF 1184 + E+Y+ F Sbjct 265 FLGEQYESGTDEDF 278 Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust. Identities = 52/245 (21%), Positives = 101/245 (41%), Gaps = 30/245 (12%) Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 Q + +K+ D I + +S++ H ++ V G G ++ ++ EY+E G Sbjct 31 QNQEIAVKIFDFLEETIKKNAEREITHLSEIDHENVIRVIGRASNGKKDYLLMEYLEEGS 90 Query 695 LDVWLRRERGHVPMAWKMVVAQ------QLASALSYLE--NKNLVHGNVCGRNILLARLG 746 L +L + W+ V Q Q A AL+YL ++ +VH ++ +N+LL Sbjct 91 LHNYL-----YGDDKWEYTVEQAVRWALQCAKALAYLHSLDRPIVHRDIKPQNMLLY--- 142 Query 747 LAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 +K+ D G+ + + ++ + ++APE + + D + FG L Sbjct 143 ---NQHEDLKICDFGLATDMSNNKTDMQGTLRYMAPEAIKHL--KYTAKCDVYSFGIMLW 197 Query 806 EICFDGEAPLQSRSPSEKEHFYQ---RQHRLP----EPSCPQ-LATLTSQCLTYEPTQRP 857 E+ +P+ + + +LP CP+ + L C+ P +RP Sbjct 198 ELMTRQLPYSHLENPNSQYAIMKAISSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRP 257 Query 858 SFRTI 862 S + I Sbjct 258 SMKEI 262 >sp|Q90XC2|NEK8_DANRE Serine/threonine-protein kinase Nek8 OS=Danio rerio OX=7955 GN=nek8 PE=2 SV=1 Length=697 Score = 87.4 bits (215), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 77/277 (28%), Positives = 128/277 (46%), Gaps = 36/277 (13%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYH 956 +K + +G G FG V L C T+ +V +K + + R + E +L+ L H Sbjct 5 EKTKVVGRGAFGIVHL-CRRRTDSA---LVILKEIPVEQMTRDERLAAQNECQVLKLLSH 60 Query 957 EHIIKY-KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMA 1012 +II+Y + ED K+L + MEY P G+L DY+ + L +L QI + Sbjct 61 PNIIEYYENFLED---KALMIAMEYAPGGTLADYIQKRCNSLLDEDTILHSFVQILLALY 117 Query 1013 YLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 ++H + +HRDL +N+LLD ++ VKIGDFG++K + + Y V +P + +PE Sbjct 118 HVHNKLILHRDLKTQNILLDKHQMIVKIGDFGISKILVSKSKAYTVV---GTPCY-ISPE 173 Query 1072 CLKEYKFYYASDVWSFGVTLYEL--LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 + + SD+W+ G LYEL L + + P L+++ Sbjct 174 LCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMS---------------- 217 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 G P D+ E+ L+ N + S RP ++ Sbjct 218 -GTFAPISDRYSPELRQLILNMLNLDPSKRPQLNEIM 253 >sp|Q1PDW3|LIPG1_ARATH Receptor-like kinase LIP1 OS=Arabidopsis thaliana OX=3702 GN=LIP1 PE=1 SV=1 Length=636 Score = 87.0 bits (214), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 72/202 (36%), Positives = 99/202 (49%), Gaps = 15/202 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG+V Y T TG++VAVK L G + E+ L L H +++K Sbjct 80 LGEGGFGRV----YKGTLQSTGQLVAVKQLDKH-GLHGNKEFLAEVLSLAKLEHPNLVKL 134 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017 G C D G++ L LV EYV GSL+D+L G + + A +G+ YLH + Sbjct 135 IGYCAD-GDQRL-LVFEYVSGGSLQDHLYEQKPGQKPMDWITRMKIAFGAAQGLDYLHDK 192 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 I+RDL A N+LLD + K+ DFGL P + + + APE + Sbjct 193 VTPAVIYRDLKASNILLDAEFYPKLCDFGLHNLEPGTGDSLFLSSRVMDTYGYSAPEYTR 252 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 SDV+SFGV L EL+T Sbjct 253 GDDLTVKSDVYSFGVVLLELIT 274 Score = 65.1 bits (157), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 61/240 (25%), Positives = 103/240 (43%), Gaps = 42/240 (18%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAW--KMVVAQQL 718 ++++ H +L + G C G + ++V EYV G L L ++ G PM W +M +A Sbjct 123 LAKLEHPNLVKLIGYCADGDQRLLVFEYVSGGSLQDHLYEQKPGQKPMDWITRMKIAFGA 182 Query 719 ASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD-------PGVGLGALS 768 A L YL +K +++ ++ NILL + KL D PG G Sbjct 183 AQGLDYLHDKVTPAVIYRDLKASNILL-------DAEFYPKLCDFGLHNLEPGTGDSLFL 235 Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF-- 826 ++ + APE G + L+ D + FG LLE+ G + + P+++++ Sbjct 236 SSRVMDTYGYSAPEYTRG--DDLTVKSDVYSFGVVLLEL-ITGRRAIDTTKPNDEQNLVA 292 Query 827 -----YQRQHRLPEPSCP------------QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 ++ R P+ + P Q +TS CL EPT RP ++ L+ L Sbjct 293 WAQPIFKDPKRYPDMADPLLRKNFSERGLNQAVAITSMCLQEEPTARPLISDVMVALSFL 352 >sp|Q61UC4|KRAF1_CAEBR Raf homolog serine/threonine-protein kinase OS=Caenorhabditis briggsae OX=6238 GN=lin-45 PE=3 SV=2 Length=811 Score = 87.4 bits (215), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 72/280 (26%), Positives = 126/280 (45%), Gaps = 30/280 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V Y GT VA+K L D P + +K E+ +L+ H +++ Sbjct 485 VGSGSFGTV----YRGEFFGT---VAIKKLNVVDPTPSQMAAFKNEVAVLKKTRHLNVLL 537 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G E + ++ ++ SL ++ PR ++ ++ +Q+ GM YLH++ Sbjct 538 FMGWVR---EPEIAIITQWCEGSSLYRHIHVQEPRVEFEMSAVIDILKQVSLGMNYLHSK 594 Query 1018 HYIHRDLAARNV-LLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLK- 1074 + IHRDL N+ L+D+ VKIGDFGLA + + ++ + W APE ++ Sbjct 595 NIIHRDLKTNNIFLMDDMSTVKIGDFGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRM 654 Query 1075 --EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + SDV+SFGV +YE+L + L I + + + + Sbjct 655 QDDNPYTPQSDVYSFGVCMYEIL----------SSHLPYSNINNRDQILFMVGRGYLKPD 704 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 R P + L NC + + RP F ++ L+ + Sbjct 705 RSKIRTDTPKSLMKLYDNCIMFDRNERPVFGEVLERLRDI 744 Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 57/246 (23%), Positives = 107/246 (43%), Gaps = 31/246 (13%) Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVW 698 L V+DP+ +A AF +++ + H ++ G VR PE ++T++ E L + Sbjct 507 LNVVDPTPSQMA-AFKNEVAVLKKTRHLNVLLFMG-WVREPEIAIITQWCEGSSLYRHIH 564 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 ++ R M+ + + +Q++ ++YL +KN++H ++ NI L +K+ Sbjct 565 VQEPRVEFEMSAVIDILKQVSLGMNYLHSKNIIHRDLKTNNIFLM------DDMSTVKIG 618 Query 759 DPGVGLGALSREERVE----------RIPWLAPECLP-GGANSLSTAMDKWGFGATLLEI 807 D GL + + V I W+APE + N + D + FG + EI Sbjct 619 D--FGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGVCMYEI 676 Query 808 CFDGEAPLQSRSPSEKEHFY-QRQHRLPEPS-----CPQ-LATLTSQCLTYEPTQRPSFR 860 P + + ++ F R + P+ S P+ L L C+ ++ +RP F Sbjct 677 -LSSHLPYSNINNRDQILFMVGRGYLKPDRSKIRTDTPKSLMKLYDNCIMFDRNERPVFG 735 Query 861 TILRDL 866 +L L Sbjct 736 EVLERL 741 >sp|I1RNG8|ATG1_GIBZE Serine/threonine-protein kinase ATG1 OS=Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) OX=229533 GN=ATG1 PE=3 SV=1 Length=944 Score = 87.8 bits (216), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 80/316 (25%), Positives = 137/316 (43%), Gaps = 73/316 (23%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHII 960 ++G+G F +V L + T VA+K+++ + + R EI IL+TL H HI+ Sbjct 29 EIGKGSFAQVYLGWHKETKAA----VAIKSVELERLNKKLRENLYSEIQILKTLRHPHIV 84 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSL------RDYLPRH--------------SIGLAQL 1000 C E + L+MEY LG L R+ L H + GL ++ Sbjct 85 ALHDCIESTSH--INLIMEYCELGDLSLFIKKREKLATHPATHDMARKYPSMPNSGLHEV 142 Query 1001 LL--FAQQICEGMAYLHAQHYIHRDLAARNVLL-----------------DNDRLV---- 1037 ++ F +Q+ + +L +++Y+HRD+ +N+LL D L+ Sbjct 143 VIRHFLKQLTSALEFLRSKNYVHRDVKPQNLLLLPSQPFRDQRSRPVMQASQDSLIPISG 202 Query 1038 -------KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 K+ DFG A+ +P + SP++ APE L+ ++ +D+WS G Sbjct 203 LASLPMLKLADFGFARVLPSTSLADTL---CGSPLYM-APEILRYERYDAKADLWSVGTV 258 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 LYE+ S+ PP + A+ + +LR E E + PR E+ L+++ Sbjct 259 LYEM-----STGRPPFR-------ARNHVELLRKIEAAEDVIKFPREVSITPELKALIRS 306 Query 1151 CWETEASFRPTFENLI 1166 + R +FEN Sbjct 307 LLKRSPVERLSFENFF 322 Score = 39.7 bits (91), Expect = 0.19, Method: Compositional matrix adjust. Identities = 64/261 (25%), Positives = 103/261 (39%), Gaps = 58/261 (22%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVP------ 707 Y ++ + H H+ +H C+ +I ++ EY E G L +++++ Sbjct 68 LYSEIQILKTLRHPHIVALHD-CIESTSHINLIMEYCELGDLSLFIKKREKLATHPATHD 126 Query 708 MAWK-----------MVVA---QQLASALSYLENKNLVHGNVCGRNILL----------A 743 MA K +V+ +QL SAL +L +KN VH +V +N+LL + Sbjct 127 MARKYPSMPNSGLHEVVIRHFLKQLTSALEFLRSKNYVHRDVKPQNLLLLPSQPFRDQRS 186 Query 744 R-------------LGLAEGTSPFIKLSDPGVG--LGALSREERVERIP-WLAPECLPGG 787 R GLA + P +KL+D G L + S + + P ++APE L Sbjct 187 RPVMQASQDSLIPISGLA--SLPMLKLADFGFARVLPSTSLADTLCGSPLYMAPEIL--R 242 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE---KEHFYQRQHRLPEPS--CPQLA 842 D W G L E+ G P ++R+ E K + + P P+L Sbjct 243 YERYDAKADLWSVGTVLYEMS-TGRPPFRARNHVELLRKIEAAEDVIKFPREVSITPELK 301 Query 843 TLTSQCLTYEPTQRPSFRTIL 863 L L P +R SF Sbjct 302 ALIRSLLKRSPVERLSFENFF 322 >sp|Q9LSE1|CDG1_ARATH Serine/threonine-protein kinase CDG1 OS=Arabidopsis thaliana OX=3702 GN=CDG1 PE=1 SV=1 Length=432 Score = 85.9 bits (211), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 70/203 (34%), Positives = 103/203 (51%), Gaps = 19/203 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V TG+ +AVK L G Q + E+ +L L+H +++ Sbjct 80 IGRGGFGTVY-----KGRLSTGQNIAVKMLD-QSGIQGDKEFLVEVLMLSLLHHRNLVHL 133 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017 G C +G++ L +V EY+PLGS+ D+L S G L + A +G+A+LH + Sbjct 134 FGYCA-EGDQRL-VVYEYMPLGSVEDHLYDLSEGQEALDWKTRMKIALGAAKGLAFLHNE 191 Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECL 1073 I+RDL N+LLD+D K+ DFGLAK P + + R G + APE Sbjct 192 AQPPVIYRDLKTSNILLDHDYKPKLSDFGLAKFGPSDDMSHVSTRVMGTHG--YCAPEYA 249 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 K SD++SFGV L EL++ Sbjct 250 NTGKLTLKSDIYSFGVVLLELIS 272 Score = 44.3 bits (103), Expect = 0.007, Method: Compositional matrix adjust. Identities = 59/222 (27%), Positives = 90/222 (41%), Gaps = 36/222 (16%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 S +G+G VY+GRL GQ + V K+LD S Sbjct 78 SLIGRGGFGTVYKGRLST-----------------------GQNIAV--KMLDQSGIQGD 112 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAWK 711 F ++S + H +L + G C G + ++V EY+ G ++ L G + WK Sbjct 113 KEFLVEVLMLSLLHHRNLVHLFGYCAEGDQRLVVYEYMPLGSVEDHLYDLSEGQEALDWK 172 Query 712 --MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALS 768 M +A A L++L N+ V R++ + + L P KLSD G+ G Sbjct 173 TRMKIALGAAKGLAFLHNE--AQPPVIYRDLKTSNILLDHDYKP--KLSDFGLAKFGPSD 228 Query 769 REERVE-RIPWLAPECLPGGANS--LSTAMDKWGFGATLLEI 807 V R+ C P AN+ L+ D + FG LLE+ Sbjct 229 DMSHVSTRVMGTHGYCAPEYANTGKLTLKSDIYSFGVVLLEL 270 >sp|Q9FYK0|TMK2_ARATH Receptor-like kinase TMK2 OS=Arabidopsis thaliana OX=3702 GN=TMK2 PE=1 SV=1 Length=886 Score = 87.4 bits (215), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 71/205 (35%), Positives = 100/205 (49%), Gaps = 21/205 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 LG G FG V +DGT +AVK +++ + +K EI +L + H +++ Sbjct 553 LGRGGFGIV---YKGELHDGT--KIAVKRMESSIISGKGLDEFKSEIAVLTRVRHRNLVV 607 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSL-RDYLPRHSIGLAQL-----LLFAQQICEGMAYLH 1015 G C + E+ LV +Y+P G+L R GL L L+ A + G+ YLH Sbjct 608 LHGYCLEGNER--LLVYQYMPQGTLSRHIFYWKEEGLRPLEWTRRLIIALDVARGVEYLH 665 Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APE 1071 Q +IHRDL N+LL +D K+ DFGL + PEG + + G F Y APE Sbjct 666 TLAHQSFIHRDLKPSNILLGDDMHAKVADFGLVRLAPEGTQSIETKIAG---TFGYLAPE 722 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 + DV+SFGV L ELLT Sbjct 723 YAVTGRVTTKVDVYSFGVILMELLT 747 Score = 63.5 bits (153), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 59/235 (25%), Positives = 107/235 (46%), Gaps = 42/235 (18%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD--VWLRRERGHVPMAW-- 710 F +++++V H +L +HG C+ G E ++V +Y+ G L ++ +E G P+ W Sbjct 590 FKSEIAVLTRVRHRNLVVLHGYCLEGNERLLVYQYMPQGTLSRHIFYWKEEGLRPLEWTR 649 Query 711 KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--- 764 ++++A +A + YL ++ +H ++ NILL G K++D G+ Sbjct 650 RLIIALDVARGVEYLHTLAHQSFIHRDLKPSNILL-------GDDMHAKVADFGLVRLAP 702 Query 765 -GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 G S E ++ +LAPE G ++T +D + FG L+E+ G L E Sbjct 703 EGTQSIETKIAGTFGYLAPEYAVTG--RVTTKVDVYSFGVILMEL-LTGRKALDVARSEE 759 Query 823 KEHF--YQRQHRLPEPSCPQ------------------LATLTSQCLTYEPTQRP 857 + H + R+ + + S P+ +A L +QC + EP RP Sbjct 760 EVHLATWFRRMFINKGSFPKAIDEAMEVNEETLRSINIVAELANQCSSREPRDRP 814 >sp|P0C8M8|CCR1_MAIZE Probable serine/threonine-protein kinase CCRP1 OS=Zea mays OX=4577 GN=CCRP1 PE=1 SV=1 Length=626 Score = 87.0 bits (214), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 67/214 (31%), Positives = 111/214 (52%), Gaps = 16/214 (7%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 ++PT+ R K R LG+G F K CY+ TN +++A K + + R+ K Sbjct 28 GTEPTI---RKYSKGRMLGKGGFAK----CYEVTNLENKKVLAGKIICKASLTKSRAKQK 80 Query 946 --QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLL 1002 EI I ++L H +I++++ EDQ +++ +++E P SL D + R + ++ Sbjct 81 LISEIKIHKSLRHSNIVEFEHVFEDQ--ENVYILLELCPNQSLHDLIKRRKRLTEIEVQC 138 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 + Q+ G+ YLH++ IHRDL N+LL++ +KI DFGLA + E R+ Sbjct 139 YTLQLICGLKYLHSRRVIHRDLKLGNLLLNDKMELKICDFGLAAKLEFDGEK---RKTVC 195 Query 1063 SPVFWYAPECLK-EYKFYYASDVWSFGVTLYELL 1095 + APE ++ + Y D WS GV +Y LL Sbjct 196 GTPNYIAPEVIEGKGGHSYEVDTWSLGVIIYTLL 229 Score = 35.0 bits (79), Expect = 4.6, Method: Compositional matrix adjust. Identities = 37/158 (23%), Positives = 69/158 (44%), Gaps = 22/158 (14%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI 776 QL L YL ++ ++H R++ L L L + +K+ D G+ E+ + + Sbjct 142 QLICGLKYLHSRRVIH-----RDLKLGNLLLNDKME--LKICDFGLAAKLEFDGEKRKTV 194 Query 777 ----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR--- 829 ++APE + G S +D W G + + G P ++ S+ + Y+R Sbjct 195 CGTPNYIAPEVIEGKGGH-SYEVDTWSLGVIIYTLLV-GRPPFET---SDVKQTYKRIKA 249 Query 830 -QHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILR 864 ++ P+ L + LT +P++RPS IL+ Sbjct 250 CEYSFPDHVSVSDTAKNLVQKMLTLDPSKRPSLDEILQ 287 >sp|F4IRW0|ATG1C_ARATH Serine/threonine-protein kinase ATG1c OS=Arabidopsis thaliana OX=3702 GN=ATG1C PE=2 SV=1 Length=733 Score = 87.0 bits (214), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 74/235 (31%), Positives = 116/235 (49%), Gaps = 29/235 (12%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHI 959 R +G G F V ++ + G VA+K + D + + EI ILR + H +I Sbjct 16 RQIGSGSFSVV----WEARHRVDGTEVAIKEIAMDRLNKKLQESLMSEIFILRRINHPNI 71 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLHAQH 1018 I+ + G+ + LV+EY G L Y+ RH I A F QQ+ G+ L + Sbjct 72 IRLIDMIKSPGK--VHLVLEYCKGGDLSVYVQRHGIVPEATAKHFMQQLAAGLQVLRDNN 129 Query 1019 YIHRDLAARNVLL---DNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL +N+LL +ND +KI DFG A+++ P G + E + APE ++ Sbjct 130 IIHRDLKPQNLLLSTNENDADLKIADFGFARSLQPRG-----LAETLCGSPLYMAPEIMQ 184 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM--TVLRLTEL 1127 K+ +D+WS G L++L+T ++P T G +Q Q+ ++R TEL Sbjct 185 LQKYDAKADLWSVGAILFQLVT----GRTPFT------GNSQIQLLQNIIRSTEL 229 Score = 47.4 bits (111), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 60/275 (22%), Positives = 111/275 (40%), Gaps = 40/275 (15%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 +G G+ + V+E R RV+G+ E+ + +D + + Sbjct 17 QIGSGSFSVVWEARHRVDGT----------------------EVAIKEIAMDRLNKKLQE 54 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKM 712 + ++ +++H ++ + + ++ P + +V EY + G L V+++R G VP A Sbjct 55 SLMSEIFILRRINHPNIIRLIDM-IKSPGKVHLVLEYCKGGDLSVYVQRH-GIVPEATAK 112 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR--- 769 QQLA+ L L + N++H ++ +N+LL+ +K++D G R Sbjct 113 HFMQQLAAGLQVLRDNNIIHRDLKPQNLLLS----TNENDADLKIADFGFARSLQPRGLA 168 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 E ++APE + D W GA L ++ G P S + R Sbjct 169 ETLCGSPLYMAPEIMQ--LQKYDAKADLWSVGAILFQLV-TGRTPFTGNSQIQLLQNIIR 225 Query 830 QHRLPEP-SCPQLA----TLTSQCLTYEPTQRPSF 859 L P C L+ L + L P +R +F Sbjct 226 STELHFPGDCRDLSLDCIDLCQKLLRRNPVERLTF 260 >sp|J4W0G2|ATG1_BEAB2 Serine/threonine-protein kinase ATG1 OS=Beauveria bassiana (strain ARSEF 2860) OX=655819 GN=ATG1 PE=2 SV=1 Length=930 Score = 87.4 bits (215), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 79/316 (25%), Positives = 138/316 (44%), Gaps = 73/316 (23%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHI 959 R++G+G F +V + + + VA+K+++ + + + EI IL+TL H HI Sbjct 27 REIGKGSFAQVYMGWHKESKAA----VAIKSVELERLNKKLKENLYGEIQILKTLRHPHI 82 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSL------RDYLPRH--------------SIGLAQ 999 + C E + L+MEY LG L RD L H + GL + Sbjct 83 VALHDCVESSTH--INLIMEYCELGDLSLFIKKRDKLITHPATHDMARKYPSAPNSGLHE 140 Query 1000 LLL--FAQQICEGMAYLHAQHYIHRDLAARNVLL-----------------DNDRLV--- 1037 +++ F +Q+ + +L A++Y+HRD+ +N+LL D L+ Sbjct 141 VVIRHFLKQLSSALEFLRAKNYVHRDVKPQNLLLLPSQAFREERALPIMEASQDSLIPIS 200 Query 1038 --------KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 K+ DFG A+ +P + SP++ APE L+ ++ +D+WS G Sbjct 201 GLASLPMLKLADFGFARVLPSTSLADTL---CGSPLYM-APEILRYERYDAKADLWSVGT 256 Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149 LYE++T PP + A+ + +LR E E + PR ++ L++ Sbjct 257 VLYEMITG-----RPPFR-------ARNHVELLRKIEAAEDVIKFPREVSVTPDLKALVR 304 Query 1150 NCWETEASFRPTFENL 1165 + + R +FEN Sbjct 305 SLLKRSPVERLSFENF 320 Score = 42.0 bits (97), Expect = 0.042, Method: Compositional matrix adjust. Identities = 63/259 (24%), Positives = 99/259 (38%), Gaps = 54/259 (21%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVP------ 707 Y ++ + H H+ +H CV +I ++ EY E G L +++++ + Sbjct 67 LYGEIQILKTLRHPHIVALHD-CVESSTHINLIMEYCELGDLSLFIKKRDKLITHPATHD 125 Query 708 MAWKMVVA--------------QQLASALSYLENKNLVHGNVCGRNILL---------AR 744 MA K A +QL+SAL +L KN VH +V +N+LL Sbjct 126 MARKYPSAPNSGLHEVVIRHFLKQLSSALEFLRAKNYVHRDVKPQNLLLLPSQAFREERA 185 Query 745 LGLAEGTS------------PFIKLSDPGVG--LGALSREERVERIP-WLAPECLPGGAN 789 L + E + P +KL+D G L + S + + P ++APE L Sbjct 186 LPIMEASQDSLIPISGLASLPMLKLADFGFARVLPSTSLADTLCGSPLYMAPEIL--RYE 243 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE---KEHFYQRQHRLPE--PSCPQLATL 844 D W G L E+ G P ++R+ E K + + P P L L Sbjct 244 RYDAKADLWSVGTVLYEM-ITGRPPFRARNHVELLRKIEAAEDVIKFPREVSVTPDLKAL 302 Query 845 TSQCLTYEPTQRPSFRTIL 863 L P +R SF Sbjct 303 VRSLLKRSPVERLSFENFF 321 >sp|Q863I2|OXSR1_PIG Serine/threonine-protein kinase OSR1 OS=Sus scrofa OX=9823 GN=OXSR1 PE=2 SV=1 Length=529 Score = 86.3 bits (212), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 62/200 (31%), Positives = 98/200 (49%), Gaps = 15/200 (8%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 E VA+K + + +EI + +H +I+ Y + E L LVM+ + G Sbjct 41 EKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGG 98 Query 985 SLRDYLP------RHSIGL---AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035 S+ D + H G+ A + +++ EG+ YLH IHRD+ A N+LL D Sbjct 99 SVLDIIKHIVAKGEHKSGVLDEATIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG 158 Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092 V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAI 218 Query 1093 ELLTHCDS-SQSPPTKFLEL 1111 EL T + PP K L L Sbjct 219 ELATGAAPYHKYPPMKVLML 238 Score = 37.7 bits (86), Expect = 0.70, Method: Compositional matrix adjust. Identities = 54/227 (24%), Positives = 87/227 (38%), Gaps = 30/227 (13%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWL------RRERGHVPMAWKMVV 714 MSQ H ++ + V E +V + + G LD+ + G + A + Sbjct 67 MSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEATIATI 126 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALSRE 770 +++ L YL +H +V NILL G + G S F L+ G R+ Sbjct 127 LREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAF--LATGGDITRNKVRK 184 Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------LQS 817 V W+APE + D W FG T +E+ G AP LQ+ Sbjct 185 TFVGTPCWMAPEVME-QVRGYDFKADIWSFGITAIELA-TGAAPYHKYPPMKVLMLTLQN 242 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 PS + ++ + + + S CL +P +RP+ +LR Sbjct 243 DPPSLETGVQDKE--MLKKYGKSFRKMISLCLQKDPEKRPTAAELLR 287 >sp|O81833|SD11_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase SD1-1 OS=Arabidopsis thaliana OX=3702 GN=SD11 PE=1 SV=1 Length=815 Score = 87.0 bits (214), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 73/205 (36%), Positives = 103/205 (50%), Gaps = 24/205 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG G FG P G G+ +AVK L A+ G Q +K E+ ++ L H ++ Sbjct 506 LGRGGFG--------PVYKGKLEDGQEIAVKRLSANSG-QGVEEFKNEVKLIAKLQHRNL 556 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMAYLH 1015 ++ GCC QGE+ + L+ EY+P SL ++ R S L + + + G+ YLH Sbjct 557 VRLLGCCI-QGEECM-LIYEYMPNKSLDFFIFDERRSTELDWKKRMNIINGVARGILYLH 614 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA-PE 1071 IHRDL A NVLLDND KI DFGLAK+ G + + + Y PE Sbjct 615 QDSRLRIIHRDLKAGNVLLDNDMNPKISDFGLAKSF--GGDQSESSTNRVVGTYGYMPPE 672 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 + F SDV+SFGV + E++T Sbjct 673 YAIDGHFSVKSDVFSFGVLVLEIIT 697 Score = 53.9 bits (128), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 50/194 (26%), Positives = 88/194 (45%), Gaps = 23/194 (12%) Query 626 PLVPGR-DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 P+ G+ + GQE+ V K L + F L++++ H +L + G C++G E + Sbjct 513 PVYKGKLEDGQEIAV--KRLSANSGQGVEEFKNEVKLIAKLQHRNLVRLLGCCIQGEECM 570 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWK--MVVAQQLASALSYLENKN---LVHGNVCGRN 739 ++ EY+ + LD ++ ER + WK M + +A + YL + ++H ++ N Sbjct 571 LIYEYMPNKSLDFFIFDERRSTELDWKKRMNIINGVARGILYLHQDSRLRIIHRDLKAGN 630 Query 740 ILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERI----PWLAPECLPGGANSLST 793 +L L +P K+SD G+ G E R+ ++ PE G S Sbjct 631 VL-----LDNDMNP--KISDFGLAKSFGGDQSESSTNRVVGTYGYMPPEYAIDG--HFSV 681 Query 794 AMDKWGFGATLLEI 807 D + FG +LEI Sbjct 682 KSDVFSFGVLVLEI 695 >sp|Q54XL6|FRAY1_DICDI Serine/threonine-protein kinase fray1 OS=Dictyostelium discoideum OX=44689 GN=fray1 PE=3 SV=1 Length=574 Score = 86.7 bits (213), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 79/277 (29%), Positives = 129/277 (47%), Gaps = 34/277 (12%) Query 900 IRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHE 957 I +GEG G+V YC E VA+K ++ D PQ +E+ ++ H Sbjct 100 IEPIGEGTEGRVFKAYCIP-----LKENVAIKVVELDKMDPQFVKDVIKEVKVMNGNNHP 154 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFA--QQICEGMAYL 1014 ++I Y + + L LVM+Y+ GSL D + ++ G+ ++L + + +G+ YL Sbjct 155 NLIHYHTSFLENNQ--LWLVMDYLGGGSLADIMKFKYPDGIPEVLAVTVLKSLLKGLEYL 212 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H+ IHRDL + N+L+ D +++ DFG++ A+ E + + +P W APE + Sbjct 213 HSHQRIHRDLKSDNILIGEDGAIELADFGVS-AMFEKNTCCSRKTIVGTPC-WMAPEIIS 270 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQMTVLRLTELLERGER 1133 E + D+WSFG+T EL+ PP+K + + G L+ E Sbjct 271 ERGYNQGVDIWSFGITAIELIRGKPPGYDLPPSKV--FMNLLFGNSPSLQEEE------- 321 Query 1134 LPRPDKCPCEVYHLMKN----CWETEASFRPTFENLI 1166 DK C HL K+ C + E S RP L+ Sbjct 322 ----DKGVCS--HLYKDLVDKCLQKEPSKRPNASKLL 352 Score = 50.8 bits (120), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 58/238 (24%), Positives = 96/238 (40%), Gaps = 26/238 (11%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DV 697 V L +DP + +M+ +H +L H + + +V +Y+ G L D+ Sbjct 128 VELDKMDPQ---FVKDVIKEVKVMNGNNHPNLIHYHTSFLENNQLWLVMDYLGGGSLADI 184 Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + +P + V + L L YL + +H ++ NIL+ G I+L Sbjct 185 MKFKYPDGIPEVLAVTVLKSLLKGLEYLHSHQRIHRDLKSDNILIGEDGA-------IEL 237 Query 758 SDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 +D GV SR+ V W+APE + + +D W FG T +E+ G+ Sbjct 238 ADFGVSAMFEKNTCCSRKTIVGTPCWMAPEII--SERGYNQGVDIWSFGITAIEL-IRGK 294 Query 813 APLQSRSPSE--KEHFYQRQHRLPEPS----CPQL-ATLTSQCLTYEPTQRPSFRTIL 863 P PS+ + L E C L L +CL EP++RP+ +L Sbjct 295 PPGYDLPPSKVFMNLLFGNSPSLQEEEDKGVCSHLYKDLVDKCLQKEPSKRPNASKLL 352 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens OX=9606 GN=NEK9 PE=1 SV=2 Length=979 Score = 87.4 bits (215), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 78/278 (28%), Positives = 132/278 (47%), Gaps = 30/278 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEH 958 IR LG G FG+ +LY T D + +V K + + R EI IL L H++ Sbjct 55 IRVLGRGAFGEATLY--RRTEDDS--LVVWKEVDLTRLSEKERRDALNEIVILALLQHDN 110 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMAYLH 1015 II Y D +L + +EY G+L D + R L + ++ + QI ++ +H Sbjct 111 IIAYYNHFMDN--TTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIH 168 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRD+ N+ L L+K+GD+GLAK + + Y + E ++ +PE + Sbjct 169 KAGILHRDIKTLNIFLTKANLIKLGDYGLAKKL---NSEYSMAETLVGTPYYMSPELCQG 225 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL-IGIAQGQMTVLRLTELLERGERL 1134 K+ + SD+W+ G ++ELLT + + T L L + I QG +R E+ L Sbjct 226 VKYNFKSDIWAVGCVIFELLTLKRTFDA--TNPLNLCVKIVQG----IRAMEVDSSQYSL 279 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILK 1170 E+ ++ +C + + RPT + L+ P+L+ Sbjct 280 --------ELIQMVHSCLDQDPEQRPTADELLDRPLLR 309 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens OX=9606 GN=PRKCD PE=1 SV=2 Length=676 Score = 87.0 bits (214), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 76/217 (35%), Positives = 104/217 (48%), Gaps = 22/217 (10%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG--PQHRSGWKQEI 948 +FHK LG+G FGKV L G GE A+KALK D E Sbjct 350 IFHKV-------LGKGSFGKVLL----GELKGRGEYFAIKALKKDVVLIDDDVECTMVEK 398 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQI 1007 +L TL E+ C Q + L VME++ G L ++ + L + +A +I Sbjct 399 RVL-TLAAENPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEI 457 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 G+ +LH++ I+RDL NVLLD D +KI DFG+ K G R +P + Sbjct 458 MCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGES--RASTFCGTPDY- 514 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 APE L+ K+ ++ D WSFGV LYE+L QSP Sbjct 515 IAPEILQGLKYTFSVDWWSFGVLLYEMLI----GQSP 547 >sp|Q0D541|WNK5_ORYSJ Probable serine/threonine-protein kinase WNK5 OS=Oryza sativa subsp. japonica OX=39947 GN=WNK5 PE=2 SV=1 Length=327 Score = 84.3 bits (207), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 64/184 (35%), Positives = 95/184 (52%), Gaps = 16/184 (9%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 V ++AL AD P E+ +LR+L+HEHII + D+ L + E GSL Sbjct 86 VRLRAL-ADRDPAMVERLHAEVRLLRSLHHEHIIGFHKVWLDRDAGVLNFITEVCTSGSL 144 Query 987 RDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDF 1042 R+Y RH + + L +A+QI G+ +LH IHRDL NV ++ N VKIGD Sbjct 145 REYRDRHRHVSVKALKKWARQILLGLDHLHTHDPCIIHRDLNCSNVFINGNTGQVKIGDL 204 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT------ 1096 GLA V + H + + +P F APE E + + D++S+G+ + E++T Sbjct 205 GLAAIVDKTHVAHTIL---GTPEFM-APELYTE-TYTESVDIYSYGMCVLEMVTREMPYA 259 Query 1097 HCDS 1100 CDS Sbjct 260 ECDS 263 >sp|Q9FN93|Y5596_ARATH Probable LRR receptor-like serine/threonine-protein kinase At5g59680 OS=Arabidopsis thaliana OX=3702 GN=At5g59680 PE=1 SV=1 Length=887 Score = 87.0 bits (214), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 58/180 (32%), Positives = 92/180 (51%), Gaps = 11/180 (6%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 E VAVK L + Q +K E+D+L ++H +++ G C D+G+ L L+ E+VP G Sbjct 603 EQVAVKLL-SQSSTQGYKEFKAEVDLLLRVHHTNLVSLVGYC-DEGDH-LALIYEFVPNG 659 Query 985 SLRDYLP----RHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLV 1037 LR +L + + L A + G+ YLH +HRD+ N+LLD Sbjct 660 DLRQHLSGKGGKPIVNWGTRLRIAAEAALGLEYLHIGCTPPMVHRDVKTTNILLDEHYKA 719 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 K+ DFGL+++ P G E + +P + PE + SDV+SFG+ L E++T+ Sbjct 720 KLADFGLSRSFPVGGESHVSTVIAGTPGY-LDPEYYHTSRLSEKSDVYSFGIVLLEMITN 778 Score = 41.6 bits (96), Expect = 0.052, Method: Compositional matrix adjust. Identities = 57/210 (27%), Positives = 87/210 (41%), Gaps = 24/210 (11%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G G E +V +K+L S F L+ +V HT+L + G C G ++ E+ Sbjct 597 GTVNGSE-QVAVKLLSQSSTQGYKEFKAEVDLLLRVHHTNLVSLVGYCDEGDHLALIYEF 655 Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLAR 744 V +G L L + G + W ++ +A + A L YL +VH +V NILL Sbjct 656 VPNGDLRQHLSGKGGKPIVNWGTRLRIAAEAALGLEYLHIGCTPPMVHRDVKTTNILLDE 715 Query 745 LGLAEGTSPFIKLSDPGVGLG-ALSREERVERI-----PWLAPECLPGGANSLSTAMDKW 798 A KL+D G+ + E V + +L PE + LS D + Sbjct 716 HYKA-------KLADFGLSRSFPVGGESHVSTVIAGTPGYLDPEYY--HTSRLSEKSDVY 766 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 FG LLE+ + ++R K H Q Sbjct 767 SFGIVLLEMITNQAVIDRNR---RKSHITQ 793 >sp|Q1DN93|ATG1_COCIM Serine/threonine-protein kinase ATG1 OS=Coccidioides immitis (strain RS) OX=246410 GN=ATG1 PE=3 SV=1 Length=969 Score = 87.4 bits (215), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 68/250 (27%), Positives = 110/250 (44%), Gaps = 63/250 (25%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHE 957 KI ++G G F V Y ++ VA+KA+ + P+ + K EI+IL+ L H Sbjct 32 KIEEIGRGSFATV----YQGIHNKYRSCVAIKAVNISSLNPKLKDNLKLEIEILKGLQHP 87 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSL------RDYLPRHSI--------------GL 997 HI+ C D+ + LVMEY LG L RD L +H + GL Sbjct 88 HIVALIDC--DESTSCIHLVMEYCALGDLSLFIRKRDTLSKHELTRDMIAKYPNPPAGGL 145 Query 998 AQLLL--FAQQICEGMAYLHAQHYIHRDLAARNVLLD-------------------NDR- 1035 ++++ F +Q+ + +L + IHRDL +N+LL+ D Sbjct 146 NEVIVRHFLKQLASALQFLRTKDLIHRDLKPQNLLLNPPPSTYAKGLLRIVPYKTREDSF 205 Query 1036 ----------LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 ++KI DFG A+++P + E + APE L+ K+ +D+W Sbjct 206 TPLVGVESLPMLKIADFGFARSLPATS----LAETLCGSPLYMAPEILRYEKYDAKADLW 261 Query 1086 SFGVTLYELL 1095 S G L+E++ Sbjct 262 SVGTVLFEMV 271 >sp|P32490|MKK1_YEAST MAP kinase kinase MKK1/SSP32 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MKK1 PE=1 SV=1 Length=508 Score = 86.3 bits (212), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 58/197 (29%), Positives = 95/197 (48%), Gaps = 13/197 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG G VS C + + L D P+++ +E+ R+ E+I++Y Sbjct 227 LGEGAGGSVS-KCKLKNGSKIFALKVINTLNTD--PEYQKQIFRELQFNRSFQSEYIVRY 283 Query 963 KGCCEDQGEKSLQLVMEYVPLGSL----RDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQ 1017 G D S+ + MEY+ SL ++ L R I L A+ + G++YLH + Sbjct 284 YGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEK 343 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ +N+LL+ + VK+ DFG++ G + F+ APE ++ Sbjct 344 KVIHRDIKPQNILLNENGQVKLCDFGVS-----GEAVNSLATTFTGTSFYMAPERIQGQP 398 Query 1078 FYYASDVWSFGVTLYEL 1094 + SDVWS G+T+ E+ Sbjct 399 YSVTSDVWSLGLTILEV 415 Score = 40.4 bits (93), Expect = 0.11, Method: Compositional matrix adjust. Identities = 42/166 (25%), Positives = 70/166 (42%), Gaps = 25/166 (15%) Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR--EE 771 +A+ + LSYL K ++H ++ +NILL G +KL D GV A++ Sbjct 329 IAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQ-------VKLCDFGVSGEAVNSLATT 381 Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-------- 823 ++APE + G S+++ D W G T+LE+ +G+ P S + Sbjct 382 FTGTSFYMAPERIQGQPYSVTS--DVWSLGLTILEVA-NGKFPCSSEKMAANIAPFELLM 438 Query 824 --EHFYQRQHRLPEPS---CPQLATLTSQCLTYEPTQRPSFRTILR 864 F PE + P + CL + +RPS R ++ Sbjct 439 WILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMIN 484 >sp|Q8W4P1|CDKC2_ARATH Cyclin-dependent kinase C-2 OS=Arabidopsis thaliana OX=3702 GN=CDKC-2 PE=1 SV=2 Length=513 Score = 85.9 bits (211), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 67/222 (30%), Positives = 104/222 (47%), Gaps = 33/222 (15%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILR 952 +K+ +GEG +G+V Y TGE+VA+K ++ D R G+ +EI IL+ Sbjct 26 FEKLEQIGEGTYGQV----YMAKEIKTGEIVALKKIRMD---NEREGFPITAIREIKILK 78 Query 953 TLYHEHIIKYKGCC-------EDQGEK-------SLQLVMEYVP--LGSLRDYLPRHSIG 996 L+HE++I K +DQG+ + +V EY+ L L D P Sbjct 79 KLHHENVIHLKEIVTSPGRDRDDQGKPDNNKYKGGIYMVFEYMDHDLTGLAD-RPGLRFT 137 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 + Q+ + +Q+ G+ Y H +HRD+ N+L+DN+ +K+ DFGLA++ H Sbjct 138 VPQIKCYMKQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSYSHDHTGNL 197 Query 1057 VREDGDSPVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096 WY P L K+ A D+WS G ELL Sbjct 198 TNR---VITLWYRPPELLLGATKYGPAIDMWSVGCIFAELLN 236 >sp|Q94C40|CIPKH_ARATH CBL-interacting serine/threonine-protein kinase 17 OS=Arabidopsis thaliana OX=3702 GN=CIPK17 PE=1 SV=1 Length=432 Score = 85.5 bits (210), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 70/208 (34%), Positives = 103/208 (50%), Gaps = 23/208 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW--KQEIDILRTLYHEH 958 R LGEG+ KV + TGE A+K ++ C + + K+EI L+ L H + Sbjct 15 RTLGEGNSAKVKF----AIDTLTGESFAIKIIEKSCITRLNVSFQIKREIRTLKVLKHPN 70 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 I++ + + + +V+E V G L D + + + Q QQ+ +G++Y H + Sbjct 71 IVRLHEVLASKTK--IYMVLECVTGGDLFDRIVSKGKLSETQGRKMFQQLIDGVSYCHNK 128 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG------DSPVFWYAPE 1071 HRDL NVLLD +KI DFGL+ ++Y REDG SP + APE Sbjct 129 GVFHRDLKLENVLLDAKGHIKITDFGLSAL----SQHY--REDGLLHTTCGSPN-YVAPE 181 Query 1072 CLKEYKFY-YASDVWSFGVTLYELLTHC 1098 L + ASD+WS GV LY +LT C Sbjct 182 VLANEGYDGAASDIWSCGVILYVILTGC 209 Score = 37.7 bits (86), Expect = 0.75, Method: Compositional matrix adjust. Identities = 43/152 (28%), Positives = 63/152 (41%), Gaps = 21/152 (14%) Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLASALS 723 + H ++ +H V + MV E V G L D + + + KM QQL +S Sbjct 66 LKHPNIVRLHEVLASKTKIYMVLECVTGGDLFDRIVSKGKLSETQGRKMF--QQLIDGVS 123 Query 724 YLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI------- 776 Y NK + H ++ N+LL G IK++D GL ALS+ R + + Sbjct 124 YCHNKGVFHRDLKLENVLLDAKG-------HIKITD--FGLSALSQHYREDGLLHTTCGS 174 Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 ++APE L A D W G L I Sbjct 175 PNYVAPEVLANEGYD-GAASDIWSCGVILYVI 205 >sp|Q96285|LRK55_ARATH L-type lectin-domain containing receptor kinase V.5 OS=Arabidopsis thaliana OX=3702 GN=LECRK55 PE=1 SV=1 Length=661 Score = 86.7 bits (213), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 85/295 (29%), Positives = 137/295 (46%), Gaps = 35/295 (12%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 K+ + LG+G FG+V Y T G+ +AVK D Q S + EI + L H Sbjct 338 FKEKQLLGKGGFGQV----YKGTLPGSDAEIAVKRTSHDS-RQGMSEFLAEISTIGRLRH 392 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMA 1012 ++++ G C + ++L LV +Y+P GSL YL R + Q + + + Sbjct 393 PNLVRLLGYCRHK--ENLYLVYDYMPNGSLDKYLNRSENQERLTWEQRFRIIKDVATALL 450 Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068 +LH Q IHRD+ NVL+DN+ ++GDFGLAK +G + + G F Y Sbjct 451 HLHQEWVQVIIHRDIKPANVLIDNEMNARLGDFGLAKLYDQGFDPETSKVAG---TFGYI 507 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 APE L+ + ++DV++FG+ + E++ C + +E + V + EL Sbjct 508 APEFLRTGRATTSTDVYAFGLVMLEVV--CGR------RIIERRAAENEEYLVDWILELW 559 Query 1129 ERG------ERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILKTVHE 1174 E G E R ++ +V ++K C AS RP ++ IL V + Sbjct 560 ENGKIFDAAEESIRQEQNRGQVELVLKLGVLCSHQAASIRPAMSVVMRILNGVSQ 614 Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust. Identities = 62/258 (24%), Positives = 107/258 (41%), Gaps = 48/258 (19%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAW--K 711 F S + ++ H +L + G C R EN+ +V +Y+ +G LD +L R + W + Sbjct 380 FLAEISTIGRLRHPNLVRLLGYC-RHKENLYLVYDYMPNGSLDKYLNRSENQERLTWEQR 438 Query 712 MVVAQQLASALSYLEN---KNLVHGNVCGRNILL-----ARLGLAEGTSPFIKLSDPGVG 763 + + +A+AL +L + ++H ++ N+L+ ARL G KL D G Sbjct 439 FRIIKDVATALLHLHQEWVQVIIHRDIKPANVLIDNEMNARL----GDFGLAKLYDQGFD 494 Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + ++APE L G + ST D + FG +LE+ G ++ R+ + Sbjct 495 ---PETSKVAGTFGYIAPEFLRTGRATTST--DVYAFGLVMLEVVC-GRRIIERRAAENE 548 Query 824 EHFY---------------------QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 E+ Q Q+R +L L C + RP+ + Sbjct 549 EYLVDWILELWENGKIFDAAEESIRQEQNRGQVELVLKLGVL---CSHQAASIRPAMSVV 605 Query 863 LRDLTRLQ--PHNLADVL 878 +R L + P NL DV+ Sbjct 606 MRILNGVSQLPDNLLDVV 623 >sp|Q9BYT3|STK33_HUMAN Serine/threonine-protein kinase 33 OS=Homo sapiens OX=9606 GN=STK33 PE=1 SV=1 Length=514 Score = 85.9 bits (211), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 61/206 (30%), Positives = 99/206 (48%), Gaps = 19/206 (9%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 R LG+G FG V + T+ T A+K + K G ++E++IL+++ HEHI Sbjct 120 RILGKGSFGIV----IEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHI 175 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQH 1018 I + E K + LVME G L++ L R + Q + +AYLH Sbjct 176 IHLEQVFETP--KKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNND 233 Query 1019 YIHRDLAARNVLL------DNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 +HRDL N+++ DN+ + +K+ DFGLA + ++ +P++ A Sbjct 234 IVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA-VKKQSRSEAMLQATCGTPIY-MA 291 Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095 PE + + + D+WS GV +Y LL Sbjct 292 PEVISAHDYSQQCDIWSIGVVMYMLL 317 Score = 53.9 bits (128), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 45/168 (27%), Positives = 78/168 (46%), Gaps = 13/168 (8%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 +++ V H H+ + V + +V E E G L L R +GH + Q LA Sbjct 165 NILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDR-KGHFSENETRWIIQSLA 223 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF---IKLSDPGVGLGALSREERVERI 776 SA++YL N ++VH ++ NI++ + L + + IK++D G+ + SR E + + Sbjct 224 SAIAYLHNNDIVHRDLKLENIMV-KSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQA 282 Query 777 P-----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 ++APE + A+ S D W G + + GE P + S Sbjct 283 TCGTPIYMAPEVI--SAHDYSQQCDIWSIGVVMY-MLLRGEPPFLASS 327 >sp|Q8S8Y8|WNK6_ARATH Probable serine/threonine-protein kinase WNK6 OS=Arabidopsis thaliana OX=3702 GN=WNK6 PE=2 SV=1 Length=567 Score = 86.3 bits (212), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 66/223 (30%), Positives = 110/223 (49%), Gaps = 20/223 (9%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD---CG 937 +P+ DPT RY++ +G+G F V Y ++ G VA ++ D Sbjct 15 DPEVLEVDPTF---RYIRYKEVIGKGAFKTV----YKAFDEVDGIEVAWNQVRIDDVLQS 67 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIG 996 P E+ +L++L H +II++ D K++ ++ E GSLR Y +H + Sbjct 68 PNCLERLYSEVRLLKSLKHNNIIRFYNSWIDDKNKTVNIITELFTSGSLRHYRKKHRKVN 127 Query 997 LAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFGLAKAVPEGHE 1053 + + +A+QI G+ YLH Q IHRDL N+ ++ N VKIGD GLA + + + Sbjct 128 MKAVKNWARQILMGLRYLHGQEPPIIHRDLKCDNIFINGNHGEVKIGDLGLATVMEQANA 187 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 + +P F APE E + +D++SFG+ + E++T Sbjct 188 KSVI----GTPEFM-APELYDE-NYNELADIYSFGMCMLEMVT 224 >sp|Q8RXG3|M2K5_ARATH Mitogen-activated protein kinase kinase 5 OS=Arabidopsis thaliana OX=3702 GN=MKK5 PE=1 SV=2 Length=348 Score = 84.3 bits (207), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 57/203 (28%), Positives = 105/203 (52%), Gaps = 17/203 (8%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+++ +G G G V + PT+ A+K + + R +EI+ILR++ H Sbjct 70 LERVNRIGSGAGGTVYKVIHTPTS----RPFALKVIYGNHEDTVRRQICREIEILRSVDH 125 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016 +++K + GE +Q+++E++ GSL H +L ++QI G+AYLH Sbjct 126 PNVVKCHDMFDHNGE--IQVLLEFMDQGSLEGA---HIWQEQELADLSRQILSGLAYLHR 180 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK-- 1074 +H +HRD+ N+L+++ + VKI DFG+++ + + + + + +PE + Sbjct 181 RHIVHRDIKPSNLLINSAKNVKIADFGVSRILAQTMDPC---NSSVGTIAYMSPERINTD 237 Query 1075 -EYKFY--YASDVWSFGVTLYEL 1094 + Y YA DVWS GV++ E Sbjct 238 LNHGRYDGYAGDVWSLGVSILEF 260 Score = 38.5 bits (88), Expect = 0.30, Method: Compositional matrix adjust. Identities = 51/240 (21%), Positives = 101/240 (42%), Gaps = 32/240 (13%) Query 641 LKVLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD--- 696 LKV+ +H D + ++ V H ++ H + E ++ E+++ G L+ Sbjct 98 LKVIYGNHEDTVRRQICREIEILRSVDHPNVVKCHDMFDHNGEIQVLLEFMDQGSLEGAH 157 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +W +E + ++Q+ S L+YL +++VH ++ N+L+ ++ +K Sbjct 158 IWQEQELADL--------SRQILSGLAYLHRRHIVHRDIKPSNLLI-------NSAKNVK 202 Query 757 LSDPGVG-LGALSRE---ERVERIPWLAPECLPGGANS---LSTAMDKWGFGATLLEICF 809 ++D GV + A + + V I +++PE + N A D W G ++LE + Sbjct 203 IADFGVSRILAQTMDPCNSSVGTIAYMSPERINTDLNHGRYDGYAGDVWSLGVSILEF-Y 261 Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT-----LTSQCLTYEPTQRPSFRTILR 864 G P + P P A+ S CL +P +R S + +L+ Sbjct 262 LGRFPFAVSRQGDWASLMCAICMSQPPEAPATASQEFRHFVSCCLQSDPPKRWSAQQLLQ 321 >sp|Q4WJJ0|MKK2_ASPFU Mitogen-activated protein kinase kinae mkk2 OS=Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) OX=330879 GN=mkk2 PE=3 SV=1 Length=503 Score = 85.9 bits (211), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 59/213 (28%), Positives = 100/213 (47%), Gaps = 19/213 (9%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 ++ + ++ LGEG G V+ C DG + A+K + D P + +E++ + Sbjct 207 EQKKIIELGSLGEGAGGAVT-RCK--LKDGK-TVFALKIITTDPNPDVKKQIVRELNFNK 262 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQI 1007 EHI +Y G D+ ++ + ME+ GSL G L A+ + Sbjct 263 DCASEHICRYYGAFMDKSTGTISIAMEFCEGGSLDSIYKEVKKLGGRTGEKVLGKIAEGV 322 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV-- 1065 G+ YLH++ IHRD+ N+LL + VK+ DFG++ + + D ++ + Sbjct 323 LNGLTYLHSRKIIHRDIKPSNILLCRNGQVKLCDFGVSGE-------FGTKGDANTFIGT 375 Query 1066 -FWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 ++ APE + + SDVWS GVTL E+ H Sbjct 376 SYYMAPERITGQSYTITSDVWSLGVTLLEVAQH 408 Score = 41.2 bits (95), Expect = 0.063, Method: Compositional matrix adjust. Identities = 52/234 (22%), Positives = 96/234 (41%), Gaps = 44/234 (19%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +QK+I +L LG+G V +L+ +GK LK++ Sbjct 207 EQKKIIELGSLGEGAGGAVTRCKLK--------DGKT----------------VFALKII 242 Query 645 --DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEYVEHGPLDVWLR 700 DP + D+ + + H+ +G + + E+ E G LD + Sbjct 243 TTDP-NPDVKKQIVRELNFNKDCASEHICRYYGAFMDKSTGTISIAMEFCEGGSLDSIYK 301 Query 701 RER---GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + G +A+ + + L+YL ++ ++H ++ NILL R G +KL Sbjct 302 EVKKLGGRTGEKVLGKIAEGVLNGLTYLHSRKIIHRDIKPSNILLCRNGQ-------VKL 354 Query 758 SDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 D GV ++ + I ++APE + G + ++++ D W G TLLE+ Sbjct 355 CDFGVSGEFGTKGDANTFIGTSYYMAPERITGQSYTITS--DVWSLGVTLLEVA 406 >sp|B0XPE4|MKK2_ASPFC Mitogen-activated protein kinase kinae mkk2 OS=Aspergillus fumigatus (strain CBS 144.89 / FGSC A1163 / CEA10) OX=451804 GN=mkk2 PE=3 SV=1 Length=503 Score = 85.9 bits (211), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 59/213 (28%), Positives = 100/213 (47%), Gaps = 19/213 (9%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 ++ + ++ LGEG G V+ C DG + A+K + D P + +E++ + Sbjct 207 EQKKIIELGSLGEGAGGAVT-RCK--LKDGK-TVFALKIITTDPNPDVKKQIVRELNFNK 262 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQI 1007 EHI +Y G D+ ++ + ME+ GSL G L A+ + Sbjct 263 DCASEHICRYYGAFMDKSTGTISIAMEFCEGGSLDSIYKEVKKLGGRTGEKVLGKIAEGV 322 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV-- 1065 G+ YLH++ IHRD+ N+LL + VK+ DFG++ + + D ++ + Sbjct 323 LNGLTYLHSRKIIHRDIKPSNILLCRNGQVKLCDFGVSGE-------FGTKGDANTFIGT 375 Query 1066 -FWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 ++ APE + + SDVWS GVTL E+ H Sbjct 376 SYYMAPERITGQSYTITSDVWSLGVTLLEVAQH 408 Score = 41.2 bits (95), Expect = 0.063, Method: Compositional matrix adjust. Identities = 52/234 (22%), Positives = 96/234 (41%), Gaps = 44/234 (19%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +QK+I +L LG+G V +L+ +GK LK++ Sbjct 207 EQKKIIELGSLGEGAGGAVTRCKLK--------DGKT----------------VFALKII 242 Query 645 --DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEYVEHGPLDVWLR 700 DP + D+ + + H+ +G + + E+ E G LD + Sbjct 243 TTDP-NPDVKKQIVRELNFNKDCASEHICRYYGAFMDKSTGTISIAMEFCEGGSLDSIYK 301 Query 701 RER---GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + G +A+ + + L+YL ++ ++H ++ NILL R G +KL Sbjct 302 EVKKLGGRTGEKVLGKIAEGVLNGLTYLHSRKIIHRDIKPSNILLCRNGQ-------VKL 354 Query 758 SDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 D GV ++ + I ++APE + G + ++++ D W G TLLE+ Sbjct 355 CDFGVSGEFGTKGDANTFIGTSYYMAPERITGQSYTITS--DVWSLGVTLLEVA 406 >sp|C0LGN2|Y3148_ARATH Probable leucine-rich repeat receptor-like serine/threonine-protein kinase At3g14840 OS=Arabidopsis thaliana OX=3702 GN=LRR-RLK PE=1 SV=1 Length=1020 Score = 87.0 bits (214), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 81/241 (34%), Positives = 118/241 (49%), Gaps = 32/241 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG V DGT ++AVK L A +R + EI ++ L H H++K Sbjct 678 IGEGGFGPVH---KGIMTDGT--VIAVKQLSAKSKQGNRE-FLNEIAMISALQHPHLVKL 731 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLL---FAQQIC----EGMAY 1013 GCC + + L LV EY+ SL L P+ + Q+ L Q+IC G+AY Sbjct 732 YGCCVEGDQ--LLLVYEYLENNSLARALFGPQET----QIPLNWPMRQKICVGIARGLAY 785 Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 LH + +HRD+ A NVLLD + KI DFGLAK E + + R G + AP Sbjct 786 LHEESRLKIVHRDIKATNVLLDKELNPKISDFGLAKLDEEENTHISTRVAG--TYGYMAP 843 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-----FLELIGIAQGQMTVLRLT 1125 E +DV+SFGV E++ H S+ S +K L+ + + + Q T+L + Sbjct 844 EYAMRGHLTDKADVYSFGVVALEIV-HGKSNTSSRSKADTFYLLDWVHVLREQNTLLEVV 902 Query 1126 E 1126 + Sbjct 903 D 903 Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 68/254 (27%), Positives = 115/254 (45%), Gaps = 46/254 (18%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAWKM- 712 F +++S + H HL ++G CV G + ++V EY+E+ L L + +P+ W M Sbjct 713 FLNEIAMISALQHPHLVKLYGCCVEGDQLLLVYEYLENNSLARALFGPQETQIPLNWPMR 772 Query 713 -VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + +A L+YL ++ +VH ++ N+LL + +P K+SD GL L Sbjct 773 QKICVGIARGLAYLHEESRLKIVHRDIKATNVLLDK-----ELNP--KISD--FGLAKLD 823 Query 769 REERV---ERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 EE R+ ++APE G L+ D + FG LEI G++ SRS + Sbjct 824 EEENTHISTRVAGTYGYMAPEYAMRG--HLTDKADVYSFGVVALEIVH-GKSNTSSRSKA 880 Query 822 EK------EHFYQRQHRLPEPSCPQLATLTSQ------------CLTYEPTQRPSFRTIL 863 + H + Q+ L E P+L T ++ C + P RPS T+ Sbjct 881 DTFYLLDWVHVLREQNTLLEVVDPRLGTDYNKQEALMMIQIGMLCTSPAPGDRPSMSTV- 939 Query 864 RDLTRLQPHNLADV 877 ++ L+ H+ +V Sbjct 940 --VSMLEGHSTVNV 951 >sp|Q9FG33|LRKS5_ARATH Probable L-type lectin-domain containing receptor kinase S.5 OS=Arabidopsis thaliana OX=3702 GN=LECRKS5 PE=2 SV=1 Length=652 Score = 86.3 bits (212), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 71/237 (30%), Positives = 115/237 (49%), Gaps = 40/237 (17%) Query 883 DSPASDPTVFHKRYLKKI-------RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935 D+ A++P F R LK+ LG+G FG V + G +AVK + ++ Sbjct 309 DNCAANPQKFKLRELKRATGNFGAENKLGQGGFGMVFKGKWQ------GRDIAVKRV-SE 361 Query 936 CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----- 990 Q + + EI + L H +++K G C ++ K LV EY+P GSL YL Sbjct 362 KSHQGKQEFIAEITTIGNLNHRNLVKLLGWCYER--KEYLLVYEYMPNGSLDKYLFLEDK 419 Query 991 --------PRHSI--GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040 R +I GL+Q L + CE + +HRD+ A NV+LD+D K+G Sbjct 420 SRSNLTWETRKNIITGLSQALEYLHNGCE-------KRILHRDIKASNVMLDSDFNAKLG 472 Query 1041 DFGLAKAVPEGH-EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 DFGLA+ + + ++ +E +P + APE + +DV++FGV + E+++ Sbjct 473 DFGLARMIQQSEMTHHSTKEIAGTPGY-MAPETFLNGRATVETDVYAFGVLMLEVVS 528 Score = 57.4 bits (137), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 62/274 (23%), Positives = 117/274 (43%), Gaps = 43/274 (16%) Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 + G+ +G+++ V K + H F + + ++H +L + G C E ++V Sbjct 344 VFKGKWQGRDIAV--KRVSEKSHQGKQEFIAEITTIGNLNHRNLVKLLGWCYERKEYLLV 401 Query 687 TEYVEHGPLDVWL---RRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNI 740 EY+ +G LD +L + R ++ + + L+ AL YL N K ++H ++ N+ Sbjct 402 YEYMPNGSLDKYLFLEDKSRSNLTWETRKNIITGLSQALEYLHNGCEKRILHRDIKASNV 461 Query 741 LL-----ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAM 795 +L A+LG G + I+ S+ + S +E ++APE G ++ T Sbjct 462 MLDSDFNAKLG-DFGLARMIQQSE----MTHHSTKEIAGTPGYMAPETFLNGRATVET-- 514 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ----------RQHRLPEPSCPQLATLT 845 D + FG +LE+ G+ P + ++ R + + + P + L Sbjct 515 DVYAFGVLMLEVV-SGKKPSYVLVKDNQNNYNNSIVNWLWELYRNGTITDAADPGMGNLF 573 Query 846 SQ------------CLTYEPTQRPSFRTILRDLT 867 + C P QRPS +T+L+ LT Sbjct 574 DKEEMKSVLLLGLACCHPNPNQRPSMKTVLKVLT 607 >sp|Q54M77|ROCO8_DICDI Probable serine/threonine-protein kinase roco8 OS=Dictyostelium discoideum OX=44689 GN=roco8 PE=3 SV=1 Length=1867 Score = 87.0 bits (214), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 69/244 (28%), Positives = 117/244 (48%), Gaps = 37/244 (15%) Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLA 998 +++E+ ++ L H +I+ KG C + +VMEY+ +GSL +L + + Sbjct 1639 FRREVWLMSGLSHSNIVLMKGFCFE----PYAIVMEYMDIGSLSSFLKKKKEDGQVLDWQ 1694 Query 999 QLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD------NDRLVKIGDFGLAKAVPE 1050 LL I GMA+LH +HRDL + N+LL N+ K+ DFGL++++ + Sbjct 1695 MLLKIVTDIASGMAFLHNITPPLVHRDLKSPNILLASHPTNPNEISAKVSDFGLSRSIVQ 1754 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 V D+P W +PE LK ++ SD++SFG+ L+E C + P +F + Sbjct 1755 NFSSKVV----DNPT-WQSPEVLKGMEYNEKSDIYSFGMILWE----CYHLELPFDEF-D 1804 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 ++ + +L G R C L+ CW + + RP+F + ILK Sbjct 1805 FKFMSTLEDNIL-------SGLRPSINQNCNRMYSSLITKCWNADPNLRPSFNS---ILK 1854 Query 1171 TVHE 1174 T++E Sbjct 1855 TLNE 1858 Score = 67.4 bits (163), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 65/226 (29%), Positives = 109/226 (48%), Gaps = 26/226 (12%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR--ERGHVPMAWKMV--VAQ 716 LMS +SH+++ + G C P I V EY++ G L +L++ E G V + W+M+ + Sbjct 1645 LMSGLSHSNIVLMKGFCFE-PYAI-VMEYMDIGSLSSFLKKKKEDGQV-LDWQMLLKIVT 1701 Query 717 QLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSP---FIKLSDPGVGLGALSR-- 769 +AS +++L N LVH ++ NILLA + T+P K+SD G+ + Sbjct 1702 DIASGMAFLHNITPPLVHRDLKSPNILLA----SHPTNPNEISAKVSDFGLSRSIVQNFS 1757 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATL-----LEICFDGEAPLQSRSPSEKE 824 + V+ W +PE L G + D + FG L LE+ FD E + S E Sbjct 1758 SKVVDNPTWQSPEVLKGME--YNEKSDIYSFGMILWECYHLELPFD-EFDFKFMSTLEDN 1814 Query 825 HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + + + ++L ++C +P RPSF +IL+ L ++ Sbjct 1815 ILSGLRPSINQNCNRMYSSLITKCWNADPNLRPSFNSILKTLNEIK 1860 >sp|O59790|ARK1_SCHPO Serine/threonine-protein kinase ark1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ark1 PE=1 SV=2 Length=355 Score = 84.3 bits (207), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 66/220 (30%), Positives = 102/220 (46%), Gaps = 18/220 (8%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 P S FH + + LG+G FG+V Y TG +VA+K L Q + Sbjct 74 PSSAGPQWREFHIGMFEIGKPLGKGKFGRV----YLAKEKKTGFIVALKTLHKSELVQSK 129 Query 942 --SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIG 996 ++EI+I L H++I++ G D EK + L++E+ G L +L R S Sbjct 130 IEKQVRREIEIQSNLRHKNILRLYGHFHD--EKRIYLILEFAGRGELYQHLRRAKRFSEE 187 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 +A +F Q+ ++YLH +H IHRD+ N+LL D +K+ DFG + P Sbjct 188 VASKYIF--QMANALSYLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNR---- 241 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 R + + PE ++ + D+WS GV YE L Sbjct 242 -RTTLCGTLDYLPPEMVEGKEHTEKVDLWSLGVLTYEFLV 280 Score = 52.4 bits (124), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 55/209 (26%), Positives = 92/209 (44%), Gaps = 17/209 (8%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLA 719 + S + H ++ ++G ++ E+ G L LRR +R +A K + Q+A Sbjct 140 IQSNLRHKNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAKRFSEEVASKYIF--QMA 197 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--REERVERIP 777 +ALSYL K+++H ++ NILL G IKLSD G + A S R + Sbjct 198 NALSYLHKKHVIHRDIKPENILL-------GIDGEIKLSDFGWSVHAPSNRRTTLCGTLD 250 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS--PSEKEHFYQRQHRLPE 835 +L PE + G + + +D W G E G P + S + + + ++P Sbjct 251 YLPPEMVEGKEH--TEKVDLWSLGVLTYEFLV-GAPPFEDMSGHSATYKRIAKVDLKIPS 307 Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILR 864 P L S+ L + P +R S ++R Sbjct 308 FVPPDARDLISRLLQHNPEKRMSLEQVMR 336 >sp|Q8AYC9|CHK1_CHICK Serine/threonine-protein kinase Chk1 OS=Gallus gallus OX=9031 GN=CHEK1 PE=1 SV=1 Length=476 Score = 85.5 bits (210), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 70/200 (35%), Positives = 98/200 (49%), Gaps = 13/200 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 ++ LGEG +G+V L N T E VAVK + K+EI I + L HE++ Sbjct 12 VQTLGEGAYGEVQL----AVNRRTEEAVAVKIVDMKRAADCPENIKKEICINKMLNHENV 67 Query 960 IKYKGCCEDQGEKSLQ-LVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +K+ G + E + Q L +EY G L D + P + + F QQ+ G+ YLH+ Sbjct 68 VKFYG---HRREGATQYLFLEYCSGGELFDRIEPDIGMPEPEAQRFFQQLIAGVVYLHSM 124 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEY 1076 HRDL N+LLD +KI DFGLA G E + G P + APE L+ Sbjct 125 GITHRDLKPENLLLDERDNLKISDFGLATVFKHNGRERLLNKMCGTLP--YVAPELLRRP 182 Query 1077 KFYYA-SDVWSFGVTLYELL 1095 +F DVW+ GV L +L Sbjct 183 EFRAEPVDVWACGVVLTAML 202 >sp|Q39203|SD22_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase SD2-2 OS=Arabidopsis thaliana OX=3702 GN=SD22 PE=1 SV=1 Length=797 Score = 86.7 bits (213), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 65/199 (33%), Positives = 99/199 (50%), Gaps = 16/199 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + T G+ VAVK L+ + S ++ E+ + + H ++++ Sbjct 467 VGHGGFGAV----FKGTLPGSSTFVAVKRLERPGSGE--SEFRAEVCTIGNIQHVNLVRL 520 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL---LLFAQQICEGMAYLHA--- 1016 +G C + + LV +Y+P GSL YL R S L A +G+AYLH Sbjct 521 RGFCSENLHR--LLVYDYMPQGSLSSYLSRTSPKLLSWETRFRIALGTAKGIAYLHEGCR 578 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IH D+ N+LLD+D K+ DFGLAK + G ++ RV + APE + Sbjct 579 DCIIHCDIKPENILLDSDYNAKVSDFGLAKLL--GRDFSRVLATMRGTWGYVAPEWISGL 636 Query 1077 KFYYASDVWSFGVTLYELL 1095 +DV+SFG+TL EL+ Sbjct 637 PITTKADVYSFGMTLLELI 655 Score = 41.6 bits (96), Expect = 0.057, Method: Compositional matrix adjust. Identities = 44/163 (27%), Positives = 72/163 (44%), Gaps = 20/163 (12%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F + + H +L + G C ++V +Y+ G L +L R + ++W + Sbjct 502 FRAEVCTIGNIQHVNLVRLRGFCSENLHRLLVYDYMPQGSLSSYLSRTSPKL-LSWETRF 560 Query 713 VVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LG-A 766 +A A ++YL ++H ++ NILL A K+SD G+ LG Sbjct 561 RIALGTAKGIAYLHEGCRDCIIHCDIKPENILLDSDYNA-------KVSDFGLAKLLGRD 613 Query 767 LSREERVERIPW--LAPECLPGGANSLSTAMDKWGFGATLLEI 807 SR R W +APE + G ++T D + FG TLLE+ Sbjct 614 FSRVLATMRGTWGYVAPEWISGLP--ITTKADVYSFGMTLLEL 654 >sp|Q9CAL2|CRK3_ARATH Cysteine-rich receptor-like protein kinase 3 OS=Arabidopsis thaliana OX=3702 GN=CRK3 PE=2 SV=1 Length=646 Score = 86.3 bits (212), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 70/208 (34%), Positives = 104/208 (50%), Gaps = 17/208 (8%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 Y LG+G G S+Y TN G+ VAVK L + Q + E++++ + Sbjct 322 YFSDKNKLGQG--GSGSVYKGVLTN---GKTVAVKRLFFNT-KQWVDHFFNEVNLISQVD 375 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGM 1011 H++++K GC G +SL LV EY+ SL DYL + A+ EGM Sbjct 376 HKNLVKLLGC-SITGPESL-LVYEYIANQSLHDYLFVRKDVQPLNWAKRFKIILGTAEGM 433 Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 AYLH + IHRD+ N+LL++D +I DFGLA+ PE + G + + Sbjct 434 AYLHEESNLRIIHRDIKLSNILLEDDFTPRIADFGLARLFPEDKTHISTAIAG--TLGYM 491 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLT 1096 APE + K +DV+SFGV + E++T Sbjct 492 APEYVVRGKLTEKADVYSFGVLMIEVIT 519 Score = 55.1 bits (131), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 43/163 (26%), Positives = 81/163 (50%), Gaps = 19/163 (12%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F+ +L+SQV H +L + G + GPE+++V EY+ + L +L + P+ W + Sbjct 364 FFNEVNLISQVDHKNLVKLLGCSITGPESLLVYEYIANQSLHDYLFVRKDVQPLNWAKRF 423 Query 713 VVAQQLASALSYL-ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771 + A ++YL E NL + R+I L+ + L + +P +++D GL L E+ Sbjct 424 KIILGTAEGMAYLHEESNL---RIIHRDIKLSNILLEDDFTP--RIAD--FGLARLFPED 476 Query 772 RVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 + + ++APE + G L+ D + FG ++E+ Sbjct 477 KTHISTAIAGTLGYMAPEYVVRG--KLTEKADVYSFGVLMIEV 517 >sp|P0CD62|LIMKB_DICDI Probable LIM domain-containing serine/threonine-protein kinase DDB_G0286997 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0286997 PE=3 SV=1 Length=966 Score = 86.7 bits (213), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 73/276 (26%), Positives = 119/276 (43%), Gaps = 30/276 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH--II 960 + G GKV Y G VA+K ++ + + +E+ I+ + +H Sbjct 708 IAAGASGKVYKGIYK------GRDVAIKVYSSENFCFNIDEFDREVTIMSLIDSDHPNFT 761 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQH 1018 ++ G Q +K L V E V GSLRD L L L A I M +LH+ Sbjct 762 RFYGA-NKQNKKYLFHVSELVKSGSLRDLLLDKEKPLLYFTQLSIASDIANAMKHLHSIG 820 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRDL + NVL+ D K+ DFG ++ V + G S + +PE K + Sbjct 821 VIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLAK--HMTMNLGTS--CYMSPELFKGNGY 876 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 DV++FG+ L+E++ + ++ + + ++ +G+R P Sbjct 877 DETCDVYAFGIVLWEIIARKEPYEN---------------INSWSIPVMVAKGDRPTIPA 921 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 CP E L+K CW + RP+F+ + LK + E Sbjct 922 DCPSEYSKLIKACWTDKPKKRPSFKEICDTLKKISE 957 Score = 45.8 bits (107), Expect = 0.003, Method: Compositional matrix adjust. Identities = 55/228 (24%), Positives = 103/228 (45%), Gaps = 28/228 (12%) Query 655 FYETASLMSQVSHTHLAFV--HGVCVRGPENIM-VTEYVEHGPL-DVWLRRERGHVPMAW 710 F ++MS + H F +G + + + V+E V+ G L D+ L +E+ P+ + Sbjct 743 FDREVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSELVKSGSLRDLLLDKEK---PLLY 799 Query 711 --KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSD-PGVG 763 ++ +A +A+A+ +L + ++H ++ N+L+ A+ GTS + L+ + Sbjct 800 FTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGTSRNVDLAKHMTMN 859 Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 LG +++PE G N D + FG L EI E P ++ + Sbjct 860 LGTSC---------YMSPELFKG--NGYDETCDVYAFGIVLWEIIARKE-PYENINSWSI 907 Query 824 EHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + R P+ CP + + L C T +P +RPSF+ I L ++ Sbjct 908 PVMVAKGDRPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTLKKI 955 >sp|O80397|M2K4_ARATH Mitogen-activated protein kinase kinase 4 OS=Arabidopsis thaliana OX=3702 GN=MKK4 PE=1 SV=1 Length=366 Score = 84.3 bits (207), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 59/208 (28%), Positives = 107/208 (51%), Gaps = 19/208 (9%) Query 894 KRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 K Y +R +G G G V + P++ + A+K + + R +EI+IL Sbjct 74 KNYSDLVRGNRIGSGAGGTVYKVIHRPSS----RLYALKVIYGNHEETVRRQICREIEIL 129 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011 R + H +++K + GE +Q+++E++ GSL H QL ++QI G+ Sbjct 130 RDVNHPNVVKCHEMFDQNGE--IQVLLEFMDKGSLEGA---HVWKEQQLADLSRQILSGL 184 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 AYLH++H +HRD+ N+L+++ + VKI DFG+++ + + + + + +PE Sbjct 185 AYLHSRHIVHRDIKPSNLLINSAKNVKIADFGVSRILAQTMDPC---NSSVGTIAYMSPE 241 Query 1072 ----CLKEYKFY-YASDVWSFGVTLYEL 1094 L + K+ YA D+WS GV++ E Sbjct 242 RINTDLNQGKYDGYAGDIWSLGVSILEF 269 Score = 39.7 bits (91), Expect = 0.16, Method: Compositional matrix adjust. Identities = 50/240 (21%), Positives = 104/240 (43%), Gaps = 32/240 (13%) Query 641 LKVLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD--- 696 LKV+ +H + + ++ V+H ++ H + + E ++ E+++ G L+ Sbjct 107 LKVIYGNHEETVRRQICREIEILRDVNHPNVVKCHEMFDQNGEIQVLLEFMDKGSLEGAH 166 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 VW ++ + ++Q+ S L+YL ++++VH ++ N+L+ ++ +K Sbjct 167 VWKEQQLADL--------SRQILSGLAYLHSRHIVHRDIKPSNLLI-------NSAKNVK 211 Query 757 LSDPGVG-LGALSRE---ERVERIPWLAPECLPGGANSLS---TAMDKWGFGATLLEICF 809 ++D GV + A + + V I +++PE + N A D W G ++LE + Sbjct 212 IADFGVSRILAQTMDPCNSSVGTIAYMSPERINTDLNQGKYDGYAGDIWSLGVSILEF-Y 270 Query 810 DGEAPLQSRSPSEKEHF-----YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 G P + + P + P+ S CL EP +R S +L+ Sbjct 271 LGRFPFPVSRQGDWASLMCAICMSQPPEAPATASPEFRHFISCCLQREPGKRRSAMQLLQ 330 >sp|Q8TGI1|ATG1_PICPA Serine/threonine-protein kinase ATG1 OS=Komagataella pastoris OX=4922 GN=ATG1 PE=3 SV=1 Length=796 Score = 86.7 bits (213), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 78/315 (25%), Positives = 133/315 (42%), Gaps = 67/315 (21%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959 ++G G F V Y N T VA+K++ + + EI IL+ L H H+ Sbjct 14 EIGRGSFANV----YKGYNSKTQVSVAIKSVIKSRLRNKKLIENLEVEISILKNLKHPHV 69 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------------------PRHSIGL 997 + C +Q + L+MEY LG L ++ P +S GL Sbjct 70 VALLDC--EQSKHYFHLLMEYCSLGDLSYFITKREELISNHPLITGVFKKYPSPENSKGL 127 Query 998 AQLLL--FAQQICEGMAYLHAQHYIHRDLAARNVLLD--------NDR---------LVK 1038 +++ F QQ+ + +L +Q+ +HRD+ +N+LL DR ++K Sbjct 128 NEVITINFVQQLASALKFLRSQNLVHRDIKPQNLLLSPPVSREVFEDRKYTGLWELPVLK 187 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 I DFG A+ +P + E + APE L+ K+ +D+WS G +YE+ Sbjct 188 IADFGFARFLPATS----MAETLCGSPLYMAPEILRYEKYNAKADLWSVGAVVYEM---- 239 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 S +PP A + +LR E + P+ + P E+ L+ + +A+ Sbjct 240 -SVGTPPFP-------AHNHVELLRNIERQKDKISFPKVAQVPPEIIQLICGLLKQQATE 291 Query 1159 RPTFENLI--PILKT 1171 R +F+ P++ T Sbjct 292 RMSFQEFFNDPVITT 306 Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 60/206 (29%), Positives = 92/206 (45%), Gaps = 31/206 (15%) Query 715 AQQLASALSYLENKNLVHGNVCGRNILLA------------RLGLAEGTSPFIKLSDPGV 762 QQLASAL +L ++NLVH ++ +N+LL+ GL E P +K++D G Sbjct 136 VQQLASALKFLRSQNLVHRDIKPQNLLLSPPVSREVFEDRKYTGLWE--LPVLKIADFGF 193 Query 763 G--LGALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 L A S E + P ++APE L + D W GA + E+ G P + + Sbjct 194 ARFLPATSMAETLCGSPLYMAPEIL--RYEKYNAKADLWSVGAVVYEMSV-GTPPFPAHN 250 Query 820 PSEKEHFYQRQH-RLPEPSC----PQLATLTSQCLTYEPTQRPSFRTILRD---LTRLQP 871 E +RQ ++ P P++ L L + T+R SF+ D T+LQP Sbjct 251 HVELLRNIERQKDKISFPKVAQVPPEIIQLICGLLKQQATERMSFQEFFNDPVITTKLQP 310 Query 872 HNLADVLTVNPDSPASDPTVFHKRYL 897 + +L P + D +F YL Sbjct 311 CSDEPLL---PQNQHIDENLFISEYL 333 >sp|Q8H1E3|PBL17_ARATH Probable serine/threonine-protein kinase PBL17 OS=Arabidopsis thaliana OX=3702 GN=PBL17 PE=1 SV=1 Length=442 Score = 85.1 bits (209), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 79/240 (33%), Positives = 112/240 (47%), Gaps = 19/240 (8%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYL--KKIRD---LGEGHFGKVSLYCYDPTN--D 921 L P N+ D L NP D + + + K+ R LGEG FG V D + Sbjct 58 LAPKNIKD-LQSNPGYENVDIFTYEEMKIATKQFRPDYILGEGGFGVVYKGVIDESVRVG 116 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG-CCEDQGEKSLQLVMEY 980 VA+K L + G Q W E++ L L H +++K G CCED LV EY Sbjct 117 FKSTKVAIKELNPE-GFQGDREWLAEVNYLGQLSHPNLVKLIGYCCEDDHR---LLVYEY 172 Query 981 VPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHA--QHYIHRDLAARNVLLDNDR 1035 + +GSL +L R ++ + + A +G+A+LH + I+RDL N+LLD Sbjct 173 MAMGSLEKHLFRRVGCTLTWTKRMKIALDAAKGLAFLHGAERSIIYRDLKTANILLDEGY 232 Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 K+ DFGLAK P G + + V + APE + SDV+ FGV L E+L Sbjct 233 NAKLSDFGLAKDGPRGDQTH-VSTRVMGTYGYAAPEYVMTGHLTSRSDVYGFGVLLLEML 291 Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 66/265 (25%), Positives = 113/265 (43%), Gaps = 40/265 (15%) Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 + +V +K L+P + + + Q+SH +L + G C ++V EY+ G Sbjct 118 KSTKVAIKELNPEGFQGDREWLAEVNYLGQLSHPNLVKLIGYCCEDDHRLLVYEYMAMGS 177 Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHG---NVCGRNILLARLGLAE 749 L+ L R G + W +M +A A L++L HG ++ R++ A + L E Sbjct 178 LEKHLFRRVG-CTLTWTKRMKIALDAAKGLAFL------HGAERSIIYRDLKTANILLDE 230 Query 750 GTSPFIKLSDPGVGL-GALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGAT 803 G + KLSD G+ G + V + APE + G L++ D +GFG Sbjct 231 GYNA--KLSDFGLAKDGPRGDQTHVSTRVMGTYGYAAPEYVMTG--HLTSRSDVYGFGVL 286 Query 804 LLEICFDGEAPLQSRSPSEKE---------HFYQRQHRLPEP---------SCPQLATLT 845 LLE+ A +SR+ E + ++ R+ +P + ++A L Sbjct 287 LLEMLLGKRAMDKSRACREHNLVEWARPLLNHNKKLLRIIDPRMDGQYGTKALMKVAGLA 346 Query 846 SQCLTYEPTQRPSFRTILRDLTRLQ 870 QCL+ P RP ++ L L+ Sbjct 347 YQCLSQNPKGRPLMNHVVEVLETLK 371 >sp|Q8L4H4|NORK_MEDTR Nodulation receptor kinase OS=Medicago truncatula OX=3880 GN=NORK PE=1 SV=2 Length=925 Score = 86.7 bits (213), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 78/278 (28%), Positives = 129/278 (46%), Gaps = 28/278 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG V Y T D G+ VAVK +++ Q + E+++L + HE+++ Sbjct 602 IGEGGFGSV----YRGTLDD-GQEVAVK-VRSSTSTQGTREFDNELNLLSAIQHENLVPL 655 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHA- 1016 G C + ++ L V ++ GSL D L R + L A G+AYLH Sbjct 656 LGYCNEYDQQIL--VYPFMSNGSLLDRLYGEASKRKILDWPTRLSIALGAARGLAYLHTF 713 Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECL 1073 + IHRD+ + N+LLD K+ DFG +K P EG Y + G + + PE Sbjct 714 PGRSVIHRDVKSSNILLDQSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAG--YLDPEYY 771 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSP-----PTKFLELIGIAQGQMTVLRLTELL 1128 K + SDV+SFGV L E++ S + P P L+ A+ + ++ E++ Sbjct 772 KTQQLSEKSDVFSFGVVLLEIV----SGREPLNIKRPRIEWSLVEWAKPYIRASKVDEIV 827 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + G + + V + C E +++RP +++ Sbjct 828 DPGIKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIV 865 Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 88/381 (23%), Positives = 139/381 (36%), Gaps = 89/381 (23%) Query 513 AFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPR 572 + LEG+G+++P + +L + DD F ++ P Sbjct 550 SITLEGFGKTYPMATNIIFSLP-----SKDDFF------------------IKSVSVKPF 586 Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 TL ++Q + +G+G +VY G L D Sbjct 587 TL-------EYIEQATEQYKTLIGEGGFGSVYRGTL-----------------------D 616 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 GQE V +KV + F +L+S + H +L + G C + I+V ++ + Sbjct 617 DGQE--VAVKVRSSTSTQGTREFDNELNLLSAIQHENLVPLLGYCNEYDQQILVYPFMSN 674 Query 693 GPLDVWLRRERGHVP----MAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLA 743 G L L R G + W ++ +A A L+YL ++++H +V NILL Sbjct 675 GSL---LDRLYGEASKRKILDWPTRLSIALGAARGLAYLHTFPGRSVIHRDVKSSNILLD 731 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 + A+ P G +S E R +L PE LS D + FG Sbjct 732 QSMCAKVADFGFSKYAPQEGDSYVSLEVR-GTAGYLDPEYYK--TQQLSEKSDVFSFGVV 788 Query 804 LLEICFDGEAPLQSRSPS------EKEHFYQRQHRLPEPSCP------------QLATLT 845 LLEI G PL + P E Y R ++ E P ++ + Sbjct 789 LLEIV-SGREPLNIKRPRIEWSLVEWAKPYIRASKVDEIVDPGIKGGYHAEALWRVVEVA 847 Query 846 SQCLTYEPTQRPSFRTILRDL 866 QCL T RP I+R+L Sbjct 848 LQCLEPYSTYRPCMVDIVREL 868 >sp|Q9R011|PLK3_RAT Serine/threonine-protein kinase PLK3 OS=Rattus norvegicus OX=10116 GN=Plk3 PE=1 SV=2 Length=647 Score = 86.3 bits (212), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 69/231 (30%), Positives = 108/231 (47%), Gaps = 14/231 (6%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 R +P LA T + +DP R K R LG+G F + CY+ T+ T Sbjct 35 RSEPGVLAGPQTPDASRLITDPR--SGRTYIKGRLLGKGGFAR----CYEATDTETSIAY 88 Query 928 AVKALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 AVK + P R EI++ R L H HI+++ ED ++ + +E S Sbjct 89 AVKVIPQSRVAKPHQREKIINEIELHRDLQHRHIVRFSHHFEDA--DNIYIFLELCSRKS 146 Query 986 LRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 L + RH++ ++ + +QI G+ YLH + +HRDL N + ++ +K+GDFGL Sbjct 147 LAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGL 206 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 A + + R + +P + APE L +DVWS G +Y LL Sbjct 207 AARLEPPEQ--RKKTICGTPNY-VAPEVLLRQGHGPEADVWSLGCVMYTLL 254 >sp|C0LGR6|Y4291_ARATH Probable LRR receptor-like serine/threonine-protein kinase At4g29180 OS=Arabidopsis thaliana OX=3702 GN=At4g29180 PE=1 SV=2 Length=913 Score = 86.7 bits (213), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 65/212 (31%), Positives = 106/212 (50%), Gaps = 26/212 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK------------ADCGPQHRSGWKQEIDI 950 +G+G FG V L + DGT +AVK + + Q ++ E ++ Sbjct 573 IGKGGFGIVYLGSLE---DGT--EIAVKMINDSSFGKSKGSSSSSSSSQVSKEFQVEAEL 627 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQI 1007 L T++H ++ + G C+D +S+ L+ EY+ G+L+DYL + + + L A Sbjct 628 LLTVHHRNLASFVGYCDDG--RSMALIYEYMANGNLQDYLSSENAEDLSWEKRLHIAIDS 685 Query 1008 CEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 +G+ YLH +HRD+ N+LL+++ KI DFGL+K PE + V +P Sbjct 686 AQGLEYLHHGCRPPIVHRDVKTANILLNDNLEAKIADFGLSKVFPEDDLSHVVTAVMGTP 745 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 + PE +K SDV+SFG+ L EL+T Sbjct 746 GY-VDPEYYNTFKLNEKSDVYSFGIVLLELIT 776 Score = 39.3 bits (90), Expect = 0.26, Method: Compositional matrix adjust. Identities = 67/278 (24%), Positives = 106/278 (38%), Gaps = 46/278 (17%) Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 ++ F A L+ V H +LA G C G ++ EY+ +G L +L E ++W Sbjct 617 VSKEFQVEAELLLTVHHRNLASFVGYCDDGRSMALIYEYMANGNLQDYLSSENAE-DLSW 675 Query 711 --KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 ++ +A A L YL + +VH +V NILL A K++D GL Sbjct 676 EKRLHIAIDSAQGLEYLHHGCRPPIVHRDVKTANILLNDNLEA-------KIAD--FGLS 726 Query 766 ALSREERVERIPWLAPECLPGGAN-------SLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + E+ + + A PG + L+ D + FG LLE+ G+ + Sbjct 727 KVFPEDDLSHVV-TAVMGTPGYVDPEYYNTFKLNEKSDVYSFGIVLLEL-ITGKRSIMKT 784 Query 819 SPSEKE---HFYQ--------------RQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 EK H+ + R H S + + C+ T RP+ Sbjct 785 DDGEKMNVVHYVEPFLKMGDIDGVVDPRLHGDFSSNSAWKFVEVAMSCVRDRGTNRPNTN 844 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898 I+ DL + LA L P S V ++Y K Sbjct 845 QIVSDLKQC----LAAELAREPKSNHEKKEVVKEKYTK 878 >sp|Q5R495|OXSR1_PONAB Serine/threonine-protein kinase OSR1 OS=Pongo abelii OX=9601 GN=OXSR1 PE=2 SV=1 Length=527 Score = 85.5 bits (210), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 61/200 (31%), Positives = 98/200 (49%), Gaps = 15/200 (8%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 E VA+K + + +EI + +H +I+ Y + E L LVM+ + G Sbjct 41 EKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGG 98 Query 985 SLRDYLP------RHSIGL---AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035 S+ D + H G+ + + +++ EG+ YLH IHRD+ A N+LL D Sbjct 99 SVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG 158 Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092 V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAI 218 Query 1093 ELLTHCDS-SQSPPTKFLEL 1111 EL T + PP K L L Sbjct 219 ELATGAAPYHKYPPMKVLML 238 Score = 37.7 bits (86), Expect = 0.71, Method: Compositional matrix adjust. Identities = 42/169 (25%), Positives = 66/169 (39%), Gaps = 23/169 (14%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALS 768 + +++ L YL +H +V NILL G + G S F L+ G Sbjct 125 TILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAF--LATGGDITRNKV 182 Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------L 815 R+ V W+APE + D W FG T +E+ G AP L Sbjct 183 RKTFVGTPCWMAPEVME-QVRGYDFKADIWSFGITAIELA-TGAAPYHKYPPMKVLMLTL 240 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 Q+ PS + ++ + + + S CL +P +RP+ +LR Sbjct 241 QNDPPSLETGVQDKE--MLKKYGKSFRKMISLCLQKDPEKRPTAAELLR 287 >sp|O95747|OXSR1_HUMAN Serine/threonine-protein kinase OSR1 OS=Homo sapiens OX=9606 GN=OXSR1 PE=1 SV=1 Length=527 Score = 85.5 bits (210), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 61/200 (31%), Positives = 98/200 (49%), Gaps = 15/200 (8%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 E VA+K + + +EI + +H +I+ Y + E L LVM+ + G Sbjct 41 EKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGG 98 Query 985 SLRDYLP------RHSIGL---AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035 S+ D + H G+ + + +++ EG+ YLH IHRD+ A N+LL D Sbjct 99 SVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG 158 Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092 V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAI 218 Query 1093 ELLTHCDS-SQSPPTKFLEL 1111 EL T + PP K L L Sbjct 219 ELATGAAPYHKYPPMKVLML 238 Score = 37.7 bits (86), Expect = 0.75, Method: Compositional matrix adjust. Identities = 42/169 (25%), Positives = 66/169 (39%), Gaps = 23/169 (14%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALS 768 + +++ L YL +H +V NILL G + G S F L+ G Sbjct 125 TILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAF--LATGGDITRNKV 182 Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------L 815 R+ V W+APE + D W FG T +E+ G AP L Sbjct 183 RKTFVGTPCWMAPEVME-QVRGYDFKADIWSFGITAIELA-TGAAPYHKYPPMKVLMLTL 240 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 Q+ PS + ++ + + + S CL +P +RP+ +LR Sbjct 241 QNDPPSLETGVQDKE--MLKKYGKSFRKMISLCLQKDPEKRPTAAELLR 287 >sp|C0LGU5|Y5457_ARATH Probable LRR receptor-like serine/threonine-protein kinase At5g45780 OS=Arabidopsis thaliana OX=3702 GN=At5g45780 PE=1 SV=1 Length=614 Score = 85.9 bits (211), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 84/296 (28%), Positives = 134/296 (45%), Gaps = 26/296 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V Y P G +VAVK LK D ++ E++++ H ++++ Sbjct 306 LGQGGFGMV-YKGYLPN----GTVVAVKRLK-DPIYTGEVQFQTEVEMIGLAVHRNLLRL 359 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRD-----YLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 G C E+ LV Y+P GS+ D Y + S+ + + A G+ YLH Q Sbjct 360 FGFCMTPEER--MLVYPYMPNGSVADRLRDNYGEKPSLDWNRRISIALGAARGLVYLHEQ 417 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRD+ A N+LLD +GDFGLAK + + + G + APE L Sbjct 418 CNPKIIHRDVKAANILLDESFEAIVGDFGLAKLLDQRDSHVTTAVRG--TIGHIAPEYLS 475 Query 1075 EYKFYYASDVWSFGVTLYELLT---HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + +DV+ FGV + EL+T D K + ++ + R E+++R Sbjct 476 TGQSSEKTDVFGFGVLILELITGHKMIDQGNGQVRKGM-ILSWVRTLKAEKRFAEMVDRD 534 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK----YQGQAPSV 1183 + D EV L C + + RP ++ +L+ + E+ Y+ +APSV Sbjct 535 LKGEFDDLVLEEVVELALLCTQPHPNLRPRMSQVLKVLEGLVEQCEGGYEARAPSV 590 >sp|Q924X7|STK33_MOUSE Serine/threonine-protein kinase 33 OS=Mus musculus OX=10090 GN=Stk33 PE=1 SV=2 Length=491 Score = 85.5 bits (210), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 58/206 (28%), Positives = 99/206 (48%), Gaps = 18/206 (9%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 R LG+G FG V ++ + TG A+K + K G ++E+ IL+T+ H+HI Sbjct 115 RILGQGSFGMV----FEAIDKETGAKWAIKKVNKEKAGSSAMKLLEREVSILKTVNHQHI 170 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I + E + + LVME G L+ + R + L Q + +AYLH + Sbjct 171 IHLEQVFE--SPQKMYLVMELCEDGELKAVMDQRGHFSENETRLIIQSLASAIAYLHNKD 228 Query 1019 YIHRDLAARNVLL------DNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 +HRDL N+++ DN+ + +K+ DFGL+ ++ +P++ A Sbjct 229 IVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPIY-MA 287 Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095 PE + + + D+WS GV ++ LL Sbjct 288 PEVINAHDYSQQCDIWSIGVIMFILL 313 Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 57/248 (23%), Positives = 105/248 (42%), Gaps = 24/248 (10%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S++ V+H H+ + V + +V E E G L + +RGH ++ Q LA Sbjct 160 SILKTVNHQHIIHLEQVFESPQKMYLVMELCEDGELKAVMD-QRGHFSENETRLIIQSLA 218 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777 SA++YL NK++VH ++ NI++ + + + + GL R E + Sbjct 219 SAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQT 278 Query 778 ------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-Q 830 ++APE + A+ S D W G + I GE P + S + ++ + Sbjct 279 TCGTPIYMAPEVI--NAHDYSQQCDIWSIGVIMF-ILLCGEPPFLANSEEKLYELIKKGE 335 Query 831 HRLPEP---SCPQLATLT-SQCLTYEPTQRPSFRTILRD-------LTRLQPHNLADVLT 879 R P S A T Q + +P R + + +L + L+ +P N+ +++ Sbjct 336 LRFENPVWESVSDSAKNTLKQLMKVDPAHRITAKELLDNQWLTGNTLSSARPTNVLEMMK 395 Query 880 VNPDSPAS 887 ++P S Sbjct 396 EWKNNPES 403 >sp|Q0D5R3|CRK6_ORYSJ Cysteine-rich receptor-like protein kinase 6 OS=Oryza sativa subsp. japonica OX=39947 GN=CRK6 PE=1 SV=1 Length=695 Score = 86.3 bits (212), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 81/279 (29%), Positives = 128/279 (46%), Gaps = 21/279 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FG V G+ +AVK L Q K E+ ++ LYH+++++ Sbjct 369 IGQGGFGMVYKGVLP-----DGQEIAVKRL-CQSSRQGIGELKSELILVAKLYHKNLVRL 422 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLR----DYLPRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017 G C +Q EK L V EY+P GSL D + + I G+ YLH Sbjct 423 IGVCLEQQEKIL--VYEYMPNGSLDIVLFDTDKNRELDWGKRFKIINGIARGLQYLHEDS 480 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRDL A N+LLD D KI DFGLAK + G + V + APE Sbjct 481 QLKIVHRDLKASNILLDFDYSPKISDFGLAK-IFGGDQSEDVTNRIAGTYGYMAPEYAMR 539 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLRLTELLE--RGE 1132 + SDV+SFGV + E++T ++ S + + ++L+ + T + EL++ G+ Sbjct 540 GNYSIKSDVFSFGVLVLEIITGRRNTGSYDSGQDVDLLNLVWEHWTRGNVVELIDPSMGD 599 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 P C H+ C + + + RPT ++ +L + Sbjct 600 HPPIEQMLKC--IHIGLLCVQKKPASRPTISSVNIMLSS 636 Score = 53.1 bits (126), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 47/158 (30%), Positives = 76/158 (48%), Gaps = 20/158 (13%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQL 718 L++++ H +L + GVC+ E I+V EY+ +G LD+ L + + W + + + Sbjct 410 LVAKLYHKNLVRLIGVCLEQQEKILVYEYMPNGSLDIVLFDTDKNRELDWGKRFKIINGI 469 Query 719 ASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERV 773 A L YL + +VH ++ NILL SP K+SD G+ G E+ Sbjct 470 ARGLQYLHEDSQLKIVHRDLKASNILLDF-----DYSP--KISDFGLAKIFGGDQSEDVT 522 Query 774 ERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 RI ++APE G S+ + D + FG +LEI Sbjct 523 NRIAGTYGYMAPEYAMRGNYSIKS--DVFSFGVLVLEI 558 >sp|Q65X23|WNK2_ORYSJ Probable serine/threonine-protein kinase WNK2 OS=Oryza sativa subsp. japonica OX=39947 GN=WNK2 PE=2 SV=1 Length=621 Score = 85.9 bits (211), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 72/241 (30%), Positives = 117/241 (49%), Gaps = 27/241 (11%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935 D+L P+ DPT + RY + LG+G F V Y + G VA +K Sbjct 10 DLLDTEPEFAEVDPTARYGRYTEV---LGKGAFKTV----YKAFDQLEGLEVAWNQIK-- 60 Query 936 CGPQHRSG-----WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 G R+ + E+ +L+TL H++IIK+ D+ ++ + E G+LR Y Sbjct 61 VGDILRNNDDLERLRSEVRLLKTLKHKNIIKFYNSWLDKKNNNINFITEVFTSGTLRQYR 120 Query 991 PRH-SIGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFGLAK 1046 +H + + L +++QI G+ YLH+ IHRDL N+ ++ N VKIGD GLA Sbjct 121 IKHKKVDVRALKKWSRQILSGLVYLHSHDPPVIHRDLKCDNIFVNGNQGEVKIGDLGLAT 180 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT----HCDSSQ 1102 + + + +P F APE E ++ D+++FG+ L EL+T +C+ S Sbjct 181 ILDNARSAHSII---GTPEFM-APELYDE-EYNELVDIYAFGMCLLELVTFEYPYCECSN 235 Query 1103 S 1103 + Sbjct 236 A 236 >sp|Q755C4|IPL1_EREGS Spindle assembly checkpoint kinase OS=Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=IPL1 PE=3 SV=1 Length=367 Score = 84.0 bits (206), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 69/260 (27%), Positives = 122/260 (47%), Gaps = 29/260 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHII 960 LG+G FG+V YC +G + A+KA++ Q+ +++E++I +L H ++ Sbjct 115 LGKGKFGRV--YCVRHIE--SGFVCALKAMEKKDIIQYNIEKQFRREVEIQSSLRHPNLT 170 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G D EK + L+MEY+ G L +L R + Q+ + + Y+H ++ Sbjct 171 QLYGYFHD--EKRVYLLMEYLVNGELYKHLKGRSHFNDVVASYYVYQMADALDYMHERNI 228 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRD+ N+++ + +K+ DFG + P+G + R+ V + +PE ++ ++ Sbjct 229 LHRDIKPENIIIGFNNTIKLTDFGWSVITPKGSK----RKTLCGTVDYLSPELIRSREYN 284 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 DVW+ GV YELL SPP + + L +L+R L PD Sbjct 285 EKVDVWALGVLTYELLV-----GSPP---------FEEESKELTYKRILKRN--LIFPDH 328 Query 1140 CPCEVYHLMKNCWETEASFR 1159 E HL+ E + R Sbjct 329 VDTEARHLISRLLEYDPGDR 348 Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 51/225 (23%), Positives = 93/225 (41%), Gaps = 21/225 (9%) Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D ++I F + S + H +L ++G ++ EY+ +G L L+ R Sbjct 144 DIIQYNIEKQFRREVEIQSSLRHPNLTQLYGYFHDEKRVYLLMEYLVNGELYKHLK-GRS 202 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG--- 761 H Q+A AL Y+ +N++H ++ NI++ G + IKL+D G Sbjct 203 HFNDVVASYYVYQMADALDYMHERNILHRDIKPENIII-------GFNNTIKLTDFGWSV 255 Query 762 VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + R+ + +L+PE + + + +D W G E+ G P + S Sbjct 256 ITPKGSKRKTLCGTVDYLSPELI--RSREYNEKVDVWALGVLTYELLV-GSPPFEEES-- 310 Query 822 EKEHFYQRQHR----LPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 KE Y+R + P+ + L S+ L Y+P R + + Sbjct 311 -KELTYKRILKRNLIFPDHVDTEARHLISRLLEYDPGDRIPLKEV 354 >sp|Q59W62|GIN4_CANAL Serine/threonine-protein kinase GIN4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=GIN4 PE=1 SV=1 Length=1349 Score = 86.7 bits (213), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 71/207 (34%), Positives = 105/207 (51%), Gaps = 21/207 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRS--------GWKQEIDIL 951 + LG G G+V L T+ TG+ AVK + K++ + G ++EI I+ Sbjct 32 KTLGRGATGRVLL----ATHQTTGQKAAVKVVSKSELQDEETEKNGDGLPYGIEREIIIM 87 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEG 1010 + L H ++++ E K+L LV+EYV G L D L R + + + + +QI G Sbjct 88 KLLTHPNVLRLYDVWE--TSKALYLVLEYVEGGELFDLLVERGPLPEVEAIKYFRQIILG 145 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 AY HA HRDL N+LLD+ VK+ DFG+A G ++ E + AP Sbjct 146 TAYCHALGICHRDLKPENLLLDSQLNVKLADFGMAALESNG----KLLETSCGSPHYAAP 201 Query 1071 ECLKEYKFY-YASDVWSFGVTLYELLT 1096 E + K++ ASDVWS GV L+ LLT Sbjct 202 EIVSGLKYHGAASDVWSCGVILFALLT 228 >sp|Q9SIB6|PBL6_ARATH Probable serine/threonine-protein kinase PBL6 OS=Arabidopsis thaliana OX=3702 GN=PBL6 PE=2 SV=1 Length=424 Score = 84.7 bits (208), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 69/202 (34%), Positives = 100/202 (50%), Gaps = 16/202 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FGKV Y + ++VA+K L + G Q + E+ L H +++K Sbjct 104 LGEGGFGKV----YKGFIEKINQVVAIKQLDRN-GAQGIREFVVEVLTLSLADHPNLVKL 158 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 G C +G + L LV EY+PLGSL ++L ++ + + A G+ YLH Sbjct 159 IGFCA-EGVQRL-LVYEYMPLGSLDNHLHDLPSGKNPLAWNTRMKIAAGAARGLEYLHDT 216 Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 I+RDL N+L+D K+ DFGLAK P G E + V + AP+ Sbjct 217 MKPPVIYRDLKCSNILIDEGYHAKLSDFGLAKVGPRGSETH-VSTRVMGTYGYCAPDYAL 275 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + + SDV+SFGV L EL+T Sbjct 276 TGQLTFKSDVYSFGVVLLELIT 297 Score = 50.4 bits (119), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 64/256 (25%), Positives = 105/256 (41%), Gaps = 29/256 (11%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K LD + F +S H +L + G C G + ++V EY+ G LD Sbjct 124 VAIKQLDRNGAQGIREFVVEVLTLSLADHPNLVKLIGFCAEGVQRLLVYEYMPLGSLDNH 183 Query 699 LRR-ERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 L G P+AW +M +A A L YL + + V R++ + + + EG Sbjct 184 LHDLPSGKNPLAWNTRMKIAAGAARGLEYLH--DTMKPPVIYRDLKCSNILIDEGYHA-- 239 Query 756 KLSDPGVG-LGALSREERVE-RIPWLAPECLPGGA--NSLSTAMDKWGFGATLLEICFDG 811 KLSD G+ +G E V R+ C P A L+ D + FG LLE+ Sbjct 240 KLSDFGLAKVGPRGSETHVSTRVMGTYGYCAPDYALTGQLTFKSDVYSFGVVLLELITGR 299 Query 812 EAPLQSRSPS-------------EKEHFYQRQHRLPEPSCP-----QLATLTSQCLTYEP 853 +A +R+ + ++++F + L E P Q + + C+ +P Sbjct 300 KAYDNTRTRNHQSLVEWANPLFKDRKNFKKMVDPLLEGDYPVRGLYQALAIAAMCVQEQP 359 Query 854 TQRPSFRTILRDLTRL 869 + RP ++ L L Sbjct 360 SMRPVIADVVMALDHL 375 >sp|Q9SEZ7|CIPKG_ARATH CBL-interacting serine/threonine-protein kinase 16 OS=Arabidopsis thaliana OX=3702 GN=CIPK16 PE=1 SV=1 Length=469 Score = 85.1 bits (209), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 72/226 (32%), Positives = 114/226 (50%), Gaps = 23/226 (10%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 +S S +F K + ++ LG G+F KV Y T TG+ VA+K +K D + R Sbjct 3 ESNRSSTVLFDKYNIGRL--LGTGNFAKV----YHGTEISTGDDVAIKVIKKDHVFKRRG 56 Query 943 GWKQ---EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ 999 +Q EI ++R L H ++++ + +K + VMEYV G L + + R L + Sbjct 57 MMEQIEREIAVMRLLRHPNVVELREVM--ATKKKIFFVMEYVNGGELFEMIDRDG-KLPE 113 Query 1000 LLL--FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYR 1056 L + QQ+ + + H++ HRD+ N+LLD + +K+ DFGL A +PEG R Sbjct 114 DLARKYFQQLISAVDFCHSRGVFHRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRR 173 Query 1057 VREDG------DSPVFWYAPECLKEYKFYYA-SDVWSFGVTLYELL 1095 D +P + APE L+ + A +D+WS G+ LY LL Sbjct 174 GSSDDLLHTRCGTPA-YVAPEVLRNKGYDGAMADIWSCGIVLYALL 218 >sp|Q869W6|MYLKG_DICDI Probable myosin light chain kinase DDB_G0275057 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0275057 PE=3 SV=1 Length=349 Score = 83.6 bits (205), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 66/200 (33%), Positives = 94/200 (47%), Gaps = 15/200 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 ++LG G F V + T T + VA+K + K +H ++EIDI++ + HE++ Sbjct 60 KELGRGAFSVVR----EGTRKTTSDKVALKYIEKKFVKKKHIEQLRREIDIMKKVKHENV 115 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 + K E + L LVME V G L + R S +Q+C G+ YLH+Q Sbjct 116 LSLKEIFE--SDSHLTLVMELVTGGELFYKIVERGSFTEKGARNVVRQVCAGVEYLHSQG 173 Query 1019 YIHRDLAARNVLLDN---DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 HRDL N+L + D +KI DFGL+K G E + APE L Sbjct 174 IAHRDLKPENLLCNGEGEDMTIKIADFGLSKIFGTG----EALETSCGTPDYVAPEVLTG 229 Query 1076 YKFYYASDVWSFGVTLYELL 1095 + A D+WS GV Y LL Sbjct 230 GSYDNAVDMWSIGVITYILL 249 Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 53/216 (25%), Positives = 89/216 (41%), Gaps = 20/216 (9%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 +M +V H ++ + + +V E V G L + ERG V +Q+ + Sbjct 106 IMKKVKHENVLSLKEIFESDSHLTLVMELVTGGEL-FYKIVERGSFTEKGARNVVRQVCA 164 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREERVERI 776 + YL ++ + H ++ N+L EG IK++D G+ G G + E Sbjct 165 GVEYLHSQGIAHRDLKPENLLCN----GEGEDMTIKIADFGLSKIFGTGE-ALETSCGTP 219 Query 777 PWLAPECLPGGANSLSTAMDKWGFGA-TLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLP 834 ++APE L GG S A+D W G T + +C G P + S + E + P Sbjct 220 DYVAPEVLTGG--SYDNAVDMWSIGVITYILLC--GFPPFYASSQNLLFEKILTADYDFP 275 Query 835 EPSCPQLA----TLTSQCLTYEPTQRPSFRTILRDL 866 EP ++ + +P QR + + L DL Sbjct 276 EPEWTHVSEHAKAFIRNLIVKDPDQRHTAKQCLDDL 311 >sp|A2VDU3|M3K7_BOVIN Mitogen-activated protein kinase kinase kinase 7 OS=Bos taurus OX=9913 GN=MAP3K7 PE=2 SV=1 Length=579 Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 78/275 (28%), Positives = 124/275 (45%), Gaps = 40/275 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + + VA+K ++++ R + E+ L + H +I+K Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 G C + + LVMEY GSL + L P A + + Q +G+AYLH+ Sbjct 93 YGACLN----PVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148 Query 1019 ---YIHRDLAARNVLL-DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL N+LL ++KI DFG A + + + G + W APE + Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTACDI----QTHMTNNKGSAA--WMAPEVFE 202 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + DV+S+G+ L+E++T + P F E+ G A R+ + G R Sbjct 203 GSNYSEKCDVFSWGIILWEVITR----RKP---FDEIGGPA------FRIMWAVHNGTRP 249 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P P + LM CW + S RP+ E ++ I+ Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIM 284 Score = 43.9 bits (102), Expect = 0.009, Method: Compositional matrix adjust. Identities = 57/233 (24%), Positives = 103/233 (44%), Gaps = 35/233 (15%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------ 707 AF +S+V+H ++ ++G C+ +V EY E G L L G P Sbjct 73 AFIVELRQLSRVNHPNIVKLYGACLNPV--CLVMEYAEGGSLYNVLH---GAEPLPYYTA 127 Query 708 ---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 M+W + +Q +A L ++ K L+H ++ N+LL +A GT +K+ D G Sbjct 128 AHAMSWCLQCSQGVA-YLHSMQPKALIHRDLKPPNLLL----VAGGT--VLKICDFGTAC 180 Query 765 GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + + W+APE G ++ S D + +G L E+ + + P+ + Sbjct 181 DIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFR 238 Query 824 EHFYQRQ-------HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + LP+P + +L ++C + +P+QRPS I++ +T L Sbjct 239 IMWAVHNGTRPPLIKNLPKP----IESLMTRCWSKDPSQRPSMEEIVKIMTHL 287 >sp|P22216|RAD53_YEAST Serine/threonine-protein kinase RAD53 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RAD53 PE=1 SV=1 Length=821 Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 83/300 (28%), Positives = 138/300 (46%), Gaps = 35/300 (12%) Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906 QCL R R+ L++ +++ L + S ++ T K + +G+G Sbjct 153 QCLEQNKVDR--IRSNLKNTSKIASPGLT---SSTASSMVANKTGIFKDFSIIDEVVGQG 207 Query 907 HFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC 966 F V TG+ AVK + + G +E+++L+ L H I++ KG Sbjct 208 AFATVK----KAIERTTGKTFAVKIISKRKVIGNMDGVTRELEVLQKLNHPRIVRLKGFY 263 Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 ED +S +VME+V G L D++ H ++G ++QI + Y+H+ HRDL Sbjct 264 ED--TESYYMVMEFVSGGDLMDFVAAHGAVGEDAGREISRQILTAIKYIHSMGISHRDLK 321 Query 1026 ARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK--------- 1074 N+L++ D LVKI DFGLAK +G+ + G + + APE ++ Sbjct 322 PDNILIEQDDPVLVKITDFGLAKV--QGNGSFMKTFCG--TLAYVAPEVIRGKDTSVSPD 377 Query 1075 --EYKFYYAS--DVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIA---QGQMTVLRLTE 1126 E + Y+S D+WS G +Y +LT H S S + + IG +G + R++E Sbjct 378 EYEERNEYSSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFRISE 437 >sp|Q06309|CRK1_LEIME Cell division protein kinase 2 homolog CRK1 OS=Leishmania mexicana OX=5665 GN=CRK1 PE=2 SV=1 Length=301 Score = 82.8 bits (203), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 64/202 (32%), Positives = 101/202 (50%), Gaps = 22/202 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIK 961 +GEG +G V Y + T VA+K ++ D + +EI +L+ L HE+I+K Sbjct 11 IGEGTYGVV----YKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRHENIVK 66 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHY 1019 C E L +V EY+ L L+ YL R + L A + F + + G+A+ H + Sbjct 67 LLDVC--HSEHRLTIVFEYLDL-DLKKYLDRENGNLDAATIQHFMRDLLRGVAFCHQRSV 123 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAK--AVPEGHEYYRVREDGDSPV-FWYAPE--CLK 1074 +HRDL +N+L+ ++ +K+GDFGL + A+P VR+ + V WY P L Sbjct 124 LHRDLKPQNLLISREKELKLGDFGLGRSFAIP-------VRKFTNEVVTLWYRPPDVLLG 176 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 ++ DVWS G E+ T Sbjct 177 SMQYGPPVDVWSVGCIFSEMAT 198 Score = 36.6 bits (83), Expect = 1.4, Method: Compositional matrix adjust. Identities = 40/184 (22%), Positives = 75/184 (41%), Gaps = 13/184 (7%) Query 630 GRDRGQELRVVLKV--LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 RD V LK LD + SL+ ++ H ++ + VC +V Sbjct 22 ARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRHENIVKLLDVCHSEHRLTIVF 81 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 EY++ L +L RE G++ A + L +++ ++++H ++ +N+L++R Sbjct 82 EYLDLD-LKKYLDRENGNLDAATIQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISR--- 137 Query 748 AEGTSPFIKLSDPGVG--LGALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFGATL 804 +KL D G+G R+ E + W P + G+ +D W G Sbjct 138 ----EKELKLGDFGLGRSFAIPVRKFTNEVVTLWYRPPDVLLGSMQYGPPVDVWSVGCIF 193 Query 805 LEIC 808 E+ Sbjct 194 SEMA 197 >sp|O22834|LRK53_ARATH Probable L-type lectin-domain containing receptor kinase V.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK53 PE=3 SV=1 Length=664 Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 77/283 (27%), Positives = 124/283 (44%), Gaps = 23/283 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG V + T G+ +AVK + D R EI + L H ++++ Sbjct 341 LGEGGFGPV----FKGTLSGSNAKIAVKRVSHDSSQGMRE-LLAEISTIGRLRHPNLVRL 395 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH--- 1015 G C + E L LV +++P GSL YL + + +Q + + ++YLH Sbjct 396 LGYCRYKEE--LYLVYDFLPNGSLDKYLYGTSDQKQLSWSQRFKIIKDVASALSYLHHGW 453 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074 IHRD+ NVL+D+ +GDFGLAK +G++ R G F Y APE ++ Sbjct 454 IHVVIHRDIKPANVLIDDKMNASLGDFGLAKVYDQGYDPQTSRVAG---TFGYMAPEIMR 510 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + +DV++FG+ + E+ CD P E + + +++E Sbjct 511 TGRPTMGTDVYAFGMFMLEV--SCDRKLFEPRAESEEAILTNWAINCWENGDIVEAATER 568 Query 1135 PRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILKTVHE 1174 R D ++ ++K C RP ++ IL V E Sbjct 569 IRQDNDKGQLELVLKLGVLCSHEAEEVRPDMATVVKILNGVSE 611 Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust. Identities = 49/208 (24%), Positives = 96/208 (46%), Gaps = 20/208 (10%) Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS---HTHLAFVHGVCVRGPE 682 P+ G G ++ +K + HD + E + +S + H +L + G C E Sbjct 348 PVFKGTLSGSNAKIAVKRVS---HDSSQGMRELLAEISTIGRLRHPNLVRLLGYCRYKEE 404 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCG 737 +V +++ +G LD +L ++W + + + +ASALSYL + ++H ++ Sbjct 405 LYLVYDFLPNGSLDKYLYGTSDQKQLSWSQRFKIIKDVASALSYLHHGWIHVVIHRDIKP 464 Query 738 RNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAM 795 N+L+ ++ + G K+ D G + RV ++APE + G ++ T Sbjct 465 ANVLIDDKMNASLGDFGLAKVYDQGYD----PQTSRVAGTFGYMAPEIMRTGRPTMGT-- 518 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEK 823 D + FG +LE+ D + + R+ SE+ Sbjct 519 DVYAFGMFMLEVSCDRKL-FEPRAESEE 545 >sp|Q5RFL3|M3K7_PONAB Mitogen-activated protein kinase kinase kinase 7 OS=Pongo abelii OX=9601 GN=MAP3K7 PE=2 SV=1 Length=606 Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 79/284 (28%), Positives = 127/284 (45%), Gaps = 40/284 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + + VA+K ++++ R + E+ L + H +I+K Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 G C + + LVMEY GSL + L P A + + Q +G+AYLH+ Sbjct 93 YGACLN----PVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148 Query 1019 ---YIHRDLAARNVLL-DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL N+LL ++KI DFG A + + + G + W APE + Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTACDI----QTHMTNNKGSAA--WMAPEVFE 202 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + DV+S+G+ L+E++T + P F E+ G A R+ + G R Sbjct 203 GSNYSEKCDVFSWGIILWEVITR----RKP---FDEIGGPA------FRIMWAVHNGTRP 249 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P P + LM CW + S RP+ E ++ I+ + + G Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293 Score = 43.9 bits (102), Expect = 0.009, Method: Compositional matrix adjust. Identities = 57/233 (24%), Positives = 103/233 (44%), Gaps = 35/233 (15%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------ 707 AF +S+V+H ++ ++G C+ +V EY E G L L G P Sbjct 73 AFIVELRQLSRVNHPNIVKLYGACLNPV--CLVMEYAEGGSLYNVLH---GAEPLPYYTA 127 Query 708 ---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 M+W + +Q +A L ++ K L+H ++ N+LL +A GT +K+ D G Sbjct 128 AHAMSWCLQCSQGVA-YLHSMQPKALIHRDLKPPNLLL----VAGGT--VLKICDFGTAC 180 Query 765 GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + + W+APE G ++ S D + +G L E+ + + P+ + Sbjct 181 DIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFR 238 Query 824 EHFYQRQ-------HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + LP+P + +L ++C + +P+QRPS I++ +T L Sbjct 239 IMWAVHNGTRPPLIKNLPKP----IESLMTRCWSKDPSQRPSMEEIVKIMTHL 287 >sp|Q95ZQ4|AAPK2_CAEEL 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Caenorhabditis elegans OX=6239 GN=aak-2 PE=1 SV=2 Length=626 Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 71/198 (36%), Positives = 96/198 (48%), Gaps = 16/198 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSG-WKQEIDILRTLYHEHII 960 LG G FGKV + ++ T VAVK L + G ++EI L H HII Sbjct 93 LGVGTFGKVKVGIHETTQ----YKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHPHII 148 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019 + + + ++ME+V G L DY+ +H + A+ F QQI G+ Y H Sbjct 149 RLYQVISTPSD--IFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMV 206 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDL N+LLD VKI DFGL+ + +G +R SP + APE + K Y Sbjct 207 VHRDLKPENLLLDEQNNVKIADFGLSNIMTDGD---FLRTSCGSP-NYAAPEVISG-KLY 261 Query 1080 YA--SDVWSFGVTLYELL 1095 DVWS GV LY LL Sbjct 262 AGPEVDVWSCGVILYALL 279 >sp|Q62073|M3K7_MOUSE Mitogen-activated protein kinase kinase kinase 7 OS=Mus musculus OX=10090 GN=Map3k7 PE=1 SV=1 Length=579 Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 79/284 (28%), Positives = 127/284 (45%), Gaps = 40/284 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + + VA+K ++++ R + E+ L + H +I+K Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 G C + + LVMEY GSL + L P A + + Q +G+AYLH+ Sbjct 93 YGACLN----PVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148 Query 1019 ---YIHRDLAARNVLL-DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL N+LL ++KI DFG A + + + G + W APE + Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTACDI----QTHMTNNKGSAA--WMAPEVFE 202 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + DV+S+G+ L+E++T + P F E+ G A R+ + G R Sbjct 203 GSNYSEKCDVFSWGIILWEVITR----RKP---FDEIGGPA------FRIMWAVHNGTRP 249 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P P + LM CW + S RP+ E ++ I+ + + G Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293 Score = 43.9 bits (102), Expect = 0.009, Method: Compositional matrix adjust. Identities = 57/233 (24%), Positives = 103/233 (44%), Gaps = 35/233 (15%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------ 707 AF +S+V+H ++ ++G C+ +V EY E G L L G P Sbjct 73 AFIVELRQLSRVNHPNIVKLYGACLNPV--CLVMEYAEGGSLYNVLH---GAEPLPYYTA 127 Query 708 ---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 M+W + +Q +A L ++ K L+H ++ N+LL +A GT +K+ D G Sbjct 128 AHAMSWCLQCSQGVA-YLHSMQPKALIHRDLKPPNLLL----VAGGT--VLKICDFGTAC 180 Query 765 GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + + W+APE G ++ S D + +G L E+ + + P+ + Sbjct 181 DIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFR 238 Query 824 EHFYQRQ-------HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + LP+P + +L ++C + +P+QRPS I++ +T L Sbjct 239 IMWAVHNGTRPPLIKNLPKP----IESLMTRCWSKDPSQRPSMEEIVKIMTHL 287 >sp|O14098|CTK1_SCHPO CTD kinase subunit alpha OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=lsk1 PE=1 SV=1 Length=593 Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 73/233 (31%), Positives = 113/233 (48%), Gaps = 42/233 (18%) Query 884 SPASDPT---VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH 940 SP S P + K +KI +GEG +GKV Y N TG++VA+K ++ + Q Sbjct 261 SPPSGPIYTYTYPKPAYEKIDQIGEGTYGKV----YKAINTVTGDLVALKRIRLE---QE 313 Query 941 RSGWK----QEIDILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEY-------VPLGSLRD 988 + G+ +E+ IL+ L H++I++ E EKS + +V EY V L S Sbjct 314 KDGFPITTVREVKILQRLRHKNIVR---LLEIMVEKSSVYMVFEYMDHDLTGVLLNSQLH 370 Query 989 YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK-- 1046 + P + ++QI E +AYLH + +HRD+ N+LL+N+ +K DFGLA+ Sbjct 371 FTP------GNIKHLSKQIFEALAYLHHRGVLHRDIKGSNILLNNNGDLKFADFGLARFN 424 Query 1047 -AVPEGHEYYRVREDGDSPVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096 + + RV W+ P L E + A D+WS G + EL T Sbjct 425 TSSKSANYTNRV------ITLWFRPPELLLGETAYDTAVDIWSAGCIVMELFT 471 Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 43/163 (26%), Positives = 76/163 (47%), Gaps = 15/163 (9%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 ++ ++ H ++ + + V MV EY++H V L + P K + ++Q+ Sbjct 327 ILQRLRHKNIVRLLEIMVEKSSVYMVFEYMDHDLTGVLLNSQLHFTPGNIKHL-SKQIFE 385 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-----ERVER 775 AL+YL ++ ++H ++ G NILL G +K +D G+ S + RV Sbjct 386 ALAYLHHRGVLHRDIKGSNILLNNNGD-------LKFADFGLARFNTSSKSANYTNRVIT 438 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + W P L G + TA+D W G ++E+ F G+ Q R Sbjct 439 L-WFRPPELLLGETAYDTAVDIWSAGCIVMEL-FTGKPFFQGR 479 >sp|P46551|CDK12_CAEEL Cyclin-dependent kinase 12 OS=Caenorhabditis elegans OX=6239 GN=cdk-12 PE=1 SV=4 Length=730 Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 65/210 (31%), Positives = 101/210 (48%), Gaps = 27/210 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILRTLYHEH 958 +GEG +G+V Y N+ TGE VA+K ++ + + G+ +EI ILR L+H++ Sbjct 317 IGEGTYGQV----YKAVNNLTGEQVALKRVRLE---NEKEGFPITAIREIKILRQLHHKN 369 Query 959 IIKYKGCCED--------QGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQIC 1008 I++ D + + LV EYV L L + Q+ +Q+ Sbjct 370 IVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQLL 429 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 EG+AY+H ++HRD+ N+L++N +KI D GLA+ + Y R WY Sbjct 430 EGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESRLYTNR----VITLWY 485 Query 1069 APE--CLKEYKFYYASDVWSFGVTLYELLT 1096 P L + ++ A DVWS G L EL T Sbjct 486 RPPELLLGDERYGPAIDVWSTGCMLGELFT 515 Score = 36.6 bits (83), Expect = 1.9, Method: Compositional matrix adjust. Identities = 63/285 (22%), Positives = 115/285 (40%), Gaps = 49/285 (17%) Query 541 GDDCFSLRRCCLPQPGETSNL-----IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHL 595 G S R+ LP P ++ + I R A+ R + S+++ + T L + Sbjct 260 GGASSSKRQDPLPMPPDSKRIATRPVITTRRGHATNRPSDSD--SWYKTNLTHYTMLDQI 317 Query 596 GQGTRTNVYEGRLRVEGSGDP-EEGKMDDED---PLVPGRD----RGQELRVVLKVLDPS 647 G+GT VY+ + G + ++++E P+ R+ R + +++++D Sbjct 318 GEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRLMDIV 377 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 DI+ M ++ T F +V EYV+H + + +E Sbjct 378 IDDIS---------MDELKRTRANFY-----------LVFEYVDHDLIGLLESKELVDFN 417 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 + +QL L+Y+ N +H ++ NIL+ G +K++D +GL L Sbjct 418 KDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGE-------LKIAD--LGLARL 468 Query 768 -SREERV--ERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +E R+ R+ W P L G A+D W G L E+ Sbjct 469 WEKESRLYTNRVITLWYRPPELLLGDERYGPAIDVWSTGCMLGEL 513 >sp|P0C8E4|M3K7_RAT Mitogen-activated protein kinase kinase kinase 7 OS=Rattus norvegicus OX=10116 GN=Map3k7 PE=1 SV=1 Length=606 Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 79/284 (28%), Positives = 127/284 (45%), Gaps = 40/284 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + + VA+K ++++ R + E+ L + H +I+K Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 G C + + LVMEY GSL + L P A + + Q +G+AYLH+ Sbjct 93 YGACLN----PVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148 Query 1019 ---YIHRDLAARNVLL-DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL N+LL ++KI DFG A + + + G + W APE + Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTACDI----QTHMTNNKGSAA--WMAPEVFE 202 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + DV+S+G+ L+E++T + P F E+ G A R+ + G R Sbjct 203 GSNYSEKCDVFSWGIILWEVITR----RKP---FDEIGGPA------FRIMWAVHNGTRP 249 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P P + LM CW + S RP+ E ++ I+ + + G Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293 Score = 43.9 bits (102), Expect = 0.010, Method: Compositional matrix adjust. Identities = 57/233 (24%), Positives = 103/233 (44%), Gaps = 35/233 (15%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------ 707 AF +S+V+H ++ ++G C+ +V EY E G L L G P Sbjct 73 AFIVELRQLSRVNHPNIVKLYGACLNPV--CLVMEYAEGGSLYNVLH---GAEPLPYYTA 127 Query 708 ---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 M+W + +Q +A L ++ K L+H ++ N+LL +A GT +K+ D G Sbjct 128 AHAMSWCLQCSQGVA-YLHSMQPKALIHRDLKPPNLLL----VAGGT--VLKICDFGTAC 180 Query 765 GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + + W+APE G ++ S D + +G L E+ + + P+ + Sbjct 181 DIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFR 238 Query 824 EHFYQRQ-------HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + LP+P + +L ++C + +P+QRPS I++ +T L Sbjct 239 IMWAVHNGTRPPLIKNLPKP----IESLMTRCWSKDPSQRPSMEEIVKIMTHL 287 >sp|Q75DK7|STE20_EREGS Serine/threonine-protein kinase STE20 OS=Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=STE20 PE=3 SV=2 Length=970 Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 54/208 (26%), Positives = 102/208 (49%), Gaps = 14/208 (7%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP+ ++ +K +G+G G V Y GT VA+K + + P+ + E Sbjct 678 DPSKIYRNLVK----IGQGASGGV----YTAYEIGTNASVAIKQMNLEKQPK-KELIINE 728 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +++ H +I+ + +G+ L ++MEY+ GSL D + + Q+ +++ Sbjct 729 ILVMKGSRHNNIVNFIDSYLLKGD--LWVIMEYMEGGSLTDVVTHCILTEGQIAAVSRET 786 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 G+ +LH++ IHRD+ + N+LL D +K+ DFG + +E R +W Sbjct 787 LRGLHFLHSKGVIHRDIKSDNILLSMDGNIKLTDFGFCAQI---NETNLKRTTMVGTPYW 843 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095 APE + ++ D+WS G+ + E++ Sbjct 844 MAPEVVSRKEYGPKVDIWSLGIMIIEMI 871 Score = 40.4 bits (93), Expect = 0.13, Method: Compositional matrix adjust. Identities = 45/192 (23%), Positives = 76/192 (40%), Gaps = 26/192 (14%) Query 685 MVTEYVEHGPLDVWLRR---ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 ++ EY+E G L + G + V+++ L +L +K ++H ++ NIL Sbjct 755 VIMEYMEGGSLTDVVTHCILTEGQI-----AAVSRETLRGLHFLHSKGVIHRDIKSDNIL 809 Query 742 LARLGLAEGTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSLSTAMDK 797 L+ G IKL+D G + L R V W+APE + +D Sbjct 810 LSMDG-------NIKLTDFGFCAQINETNLKRTTMVGTPYWMAPEVV--SRKEYGPKVDI 860 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH----RLPEPSCPQLATLTSQCLTYEP 853 W G ++E+ +GE P + +P + + + P L S CL P Sbjct 861 WSLGIMIIEM-IEGEPPYLNETPLRALYLIATNGTPKLKDADSLSPVLKRFLSWCLQVSP 919 Query 854 TQRPSFRTILRD 865 R + +L D Sbjct 920 NDRATAMELLYD 931 >sp|Q8K1R7|NEK9_MOUSE Serine/threonine-protein kinase Nek9 OS=Mus musculus OX=10090 GN=Nek9 PE=1 SV=2 Length=984 Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 61/201 (30%), Positives = 100/201 (50%), Gaps = 13/201 (6%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEH 958 IR LG G FG+ +LY T D + +V K + + R EI IL L H++ Sbjct 55 IRVLGRGAFGEATLY--RRTEDDS--LVVWKEVDLTRLSEKERRDALNEIVILALLQHDN 110 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMAYLH 1015 II Y D +L + +EY G+L D + R L + ++ + QI ++ +H Sbjct 111 IIAYYNHFMDN--TTLLIELEYCNGGNLYDKILRQKDKLFEEEMVVWYLFQIVSAVSCIH 168 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRD+ N+ L L+K+GD+GLAK + + Y + E ++ +PE + Sbjct 169 KAGILHRDIKTLNIFLTKANLIKLGDYGLAKKL---NSEYSMAETLVGTPYYMSPELCQG 225 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 K+ + SD+W+ G ++ELLT Sbjct 226 VKYNFKSDIWAVGCVIFELLT 246 >sp|O43318|M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 OS=Homo sapiens OX=9606 GN=MAP3K7 PE=1 SV=1 Length=606 Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 79/284 (28%), Positives = 127/284 (45%), Gaps = 40/284 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + + VA+K ++++ R + E+ L + H +I+K Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 G C + + LVMEY GSL + L P A + + Q +G+AYLH+ Sbjct 93 YGACLN----PVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148 Query 1019 ---YIHRDLAARNVLL-DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL N+LL ++KI DFG A + + + G + W APE + Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTACDI----QTHMTNNKGSAA--WMAPEVFE 202 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + DV+S+G+ L+E++T + P F E+ G A R+ + G R Sbjct 203 GSNYSEKCDVFSWGIILWEVITR----RKP---FDEIGGPA------FRIMWAVHNGTRP 249 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P P + LM CW + S RP+ E ++ I+ + + G Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293 Score = 43.9 bits (102), Expect = 0.010, Method: Compositional matrix adjust. Identities = 57/233 (24%), Positives = 103/233 (44%), Gaps = 35/233 (15%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP------ 707 AF +S+V+H ++ ++G C+ +V EY E G L L G P Sbjct 73 AFIVELRQLSRVNHPNIVKLYGACLNPV--CLVMEYAEGGSLYNVLH---GAEPLPYYTA 127 Query 708 ---MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 M+W + +Q +A L ++ K L+H ++ N+LL +A GT +K+ D G Sbjct 128 AHAMSWCLQCSQGVA-YLHSMQPKALIHRDLKPPNLLL----VAGGT--VLKICDFGTAC 180 Query 765 GALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + + W+APE G ++ S D + +G L E+ + + P+ + Sbjct 181 DIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFR 238 Query 824 EHFYQRQ-------HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + LP+P + +L ++C + +P+QRPS I++ +T L Sbjct 239 IMWAVHNGTRPPLIKNLPKP----IESLMTRCWSKDPSQRPSMEEIVKIMTHL 287 >sp|P70218|M4K1_MOUSE Mitogen-activated protein kinase kinase kinase kinase 1 OS=Mus musculus OX=10090 GN=Map4k1 PE=1 SV=1 Length=827 Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 61/214 (29%), Positives = 111/214 (52%), Gaps = 17/214 (8%) Query 888 DPTVFHK---RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 DP +F+K + ++ LG G +G+V + + + ++VA+K +K + + Sbjct 5 DPDIFNKDPREHYDLLQRLGGGTYGEV----FKARDKVSKDLVALKMVKMEPD-DDVATL 59 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLF 1003 ++EI +L+T H +I+ Y G + L + ME+ GSL+D Y S+ Q+ Sbjct 60 QKEILMLKTCRHANIVAYHG--SYLWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYV 117 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 +++ +G+AYLH++ IHRD+ N+L+++ VK+ DFG++ + G R + Sbjct 118 CREVLQGLAYLHSEKKIHRDIKGANILINDCGEVKLADFGISAQI--GATLARRLSFIGT 175 Query 1064 PVFWYAPECLK---EYKFYYASDVWSFGVTLYEL 1094 P +W APE + + D+WS G+T EL Sbjct 176 P-YWMAPEVAAVALKGGYNELCDIWSLGITAIEL 208 Score = 44.3 bits (103), Expect = 0.008, Method: Compositional matrix adjust. Identities = 47/187 (25%), Positives = 82/187 (44%), Gaps = 21/187 (11%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 RD+ + V LK++ D + ++ H ++ HG + + + E+ Sbjct 34 ARDKVSKDLVALKMVKMEPDDDVATLQKEILMLKTCRHANIVAYHGSYLWLQKLWICMEF 93 Query 690 VEHGPL-DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 G L D++ + G + V +++ L+YL ++ +H ++ G NIL+ G Sbjct 94 CGAGSLQDIY--QVTGSLSELQISYVCREVLQGLAYLHSEKKIHRDIKGANILINDCG-- 149 Query 749 EGTSPFIKLSDPGVG--LGA-LSREERVERIP-WLAPE----CLPGGANSLSTAMDKWGF 800 +KL+D G+ +GA L+R P W+APE L GG N L D W Sbjct 150 -----EVKLADFGISAQIGATLARRLSFIGTPYWMAPEVAAVALKGGYNELC---DIWSL 201 Query 801 GATLLEI 807 G T +E+ Sbjct 202 GITAIEL 208 >sp|P05986|KAPC_YEAST cAMP-dependent protein kinase type 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TPK3 PE=1 SV=2 Length=398 Score = 84.0 bits (206), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 64/200 (32%), Positives = 99/200 (50%), Gaps = 17/200 (9%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTLYHE 957 +R LG G FG+V L ++ G A+K LK + + E +L + H Sbjct 91 LRTLGTGSFGRVHLI----RSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHP 146 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL--LFAQQICEGMAYLH 1015 II+ G +D + + +VM+Y+ G L L R S + +A ++C + YLH Sbjct 147 FIIRMWGTFQDS--QQVFMVMDYIEGGELFSLL-RKSQRFPNPVAKFYAAEVCLALEYLH 203 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 ++ I+RDL N+LLD + +KI DFG AK VP+ Y + D + APE + Sbjct 204 SKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVT--YTLCGTPD----YIAPEVVST 257 Query 1076 YKFYYASDVWSFGVTLYELL 1095 + + D WSFGV +YE+L Sbjct 258 KPYNKSVDWWSFGVLIYEML 277 Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 45/197 (23%), Positives = 84/197 (43%), Gaps = 11/197 (6%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 ++S VSH + + G + MV +Y+E G L LR+ + P A ++ Sbjct 139 MLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQ-RFPNPVAKFYAAEVCL 197 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-WL 779 AL YL +K++++ ++ NILL + G IK++D G + P ++ Sbjct 198 ALEYLHSKDIIYRDLKPENILLDKNG-------HIKITDFGFAKYVPDVTYTLCGTPDYI 250 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP 839 APE + + ++D W FG + E+ S + E+ + + P P Sbjct 251 APEVV--STKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHP 308 Query 840 QLATLTSQCLTYEPTQR 856 L + +T + ++R Sbjct 309 DAQDLLKKLITRDLSER 325 >sp|D4AE59|STK11_RAT Serine/threonine-protein kinase STK11 OS=Rattus norvegicus OX=10116 GN=Stk11 PE=1 SV=2 Length=436 Score = 84.3 bits (207), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 59/198 (30%), Positives = 96/198 (48%), Gaps = 6/198 (3%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG +GKV D + +K K P + K+EI +LR L H ++I+ Sbjct 55 LGEGSYGKVK-EVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHRNVIQL 113 Query 963 KGCCEDQGEKSLQLVMEYVPLG--SLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 ++ ++ + +VMEY G + D +P + Q + +Q+ +G+ YLH+Q + Sbjct 114 VDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFRQLIDGLEYLHSQGIV 173 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 H+D+ N+LL + +KI D G+A+A+ R SP F PE + Sbjct 174 HKDIKPGNLLLTTNGTLKISDLGVAEALHPFAVDDTCRTSQGSPAFQ-PPEIANGLDTFS 232 Query 1080 -YASDVWSFGVTLYELLT 1096 + D+WS GVTLY + T Sbjct 233 GFKVDIWSAGVTLYNITT 250 Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 56/210 (27%), Positives = 87/210 (41%), Gaps = 15/210 (7%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 MV EY G ++ P+ +QL L YL ++ +VH ++ N+LL Sbjct 127 MVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFRQLIDGLEYLHSQGIVHKDIKPGNLLLT- 185 Query 745 LGLAEGTSPFIKLSDPGVGLG----ALSREERVER-IPWLAPECLPGGANSLST-AMDKW 798 T+ +K+SD GV A+ R + P P + G ++ S +D W Sbjct 186 ------TNGTLKISDLGVAEALHPFAVDDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIW 239 Query 799 GFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857 G TL I G P + + + E+ + +P P L+ L L YEP +R Sbjct 240 SAGVTLYNIT-TGLYPFEGDNIYKLFENIGRGDFTIPCDCAPPLSDLLRGMLEYEPAKRF 298 Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 S R I + + H LA+ L P SP + Sbjct 299 SIRQIRQHSWFRKKHPLAEALVPIPPSPDT 328 >sp|Q8C015|PAK5_MOUSE Serine/threonine-protein kinase PAK 5 OS=Mus musculus OX=10090 GN=Pak5 PE=1 SV=1 Length=719 Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 63/223 (28%), Positives = 105/223 (47%), Gaps = 28/223 (13%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 L V+P P + YL +GEG G V + T TG+ VAVK K D Sbjct 438 LVVSPGDP--------REYLDNFIKIGEGSTGIVCI----ATEKHTGKQVAVK--KMDLR 483 Query 938 PQHRSGWK-QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996 Q R E+ I+R +H++++ E L +VME++ G+L D + + Sbjct 484 KQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDE--LWVVMEFLEGGALTDIVTHTRMN 541 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG----LAKAVPEGH 1052 Q+ + + ++YLH Q IHRD+ + ++LL +D +K+ DFG ++K VP+ Sbjct 542 EEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPK-- 599 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 R+ +W APE + + D+WS G+ + E++ Sbjct 600 -----RKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMI 637 Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 52/191 (27%), Positives = 81/191 (42%), Gaps = 24/191 (13%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-D 696 +V +K +D + +M H ++ ++ + G E +V E++E G L D Sbjct 474 QVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTD 533 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 + +A V + ALSYL N+ ++H ++ +ILL G IK Sbjct 534 IVTHTRMNEEQIA---TVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGR-------IK 583 Query 757 LSDPG----VGLGALSREERVERIPWLAPEC---LPGGANSLSTAMDKWGFGATLLEICF 809 LSD G V R+ V W+APE LP G T +D W G ++E+ Sbjct 584 LSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYG-----TEVDIWSLGIMVIEM-I 637 Query 810 DGEAPLQSRSP 820 DGE P + P Sbjct 638 DGEPPYFNEPP 648 >sp|D4A280|PAK5_RAT Serine/threonine-protein kinase PAK 5 OS=Rattus norvegicus OX=10116 GN=Pak5 PE=1 SV=1 Length=718 Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 63/223 (28%), Positives = 105/223 (47%), Gaps = 28/223 (13%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 L V+P P + YL +GEG G V + T TG+ VAVK K D Sbjct 437 LVVSPGDP--------REYLDNFIKIGEGSTGIVCI----ATEKHTGKQVAVK--KMDLR 482 Query 938 PQHRSGWK-QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996 Q R E+ I+R +H++++ E L +VME++ G+L D + + Sbjct 483 KQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDE--LWVVMEFLEGGALTDIVTHTRMN 540 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG----LAKAVPEGH 1052 Q+ + + ++YLH Q IHRD+ + ++LL +D +K+ DFG ++K VP+ Sbjct 541 EEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPK-- 598 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 R+ +W APE + + D+WS G+ + E++ Sbjct 599 -----RKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMI 636 Score = 52.0 bits (123), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 52/191 (27%), Positives = 81/191 (42%), Gaps = 24/191 (13%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-D 696 +V +K +D + +M H ++ ++ + G E +V E++E G L D Sbjct 473 QVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTD 532 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 + +A V + ALSYL N+ ++H ++ +ILL G IK Sbjct 533 IVTHTRMNEEQIA---TVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGR-------IK 582 Query 757 LSDPG----VGLGALSREERVERIPWLAPEC---LPGGANSLSTAMDKWGFGATLLEICF 809 LSD G V R+ V W+APE LP G T +D W G ++E+ Sbjct 583 LSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYG-----TEVDIWSLGIMVIEM-I 636 Query 810 DGEAPLQSRSP 820 DGE P + P Sbjct 637 DGEPPYFNEPP 647 >sp|Q9FIU5|CRLK1_ARATH Calcium/calmodulin-regulated receptor-like kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CRLK1 PE=1 SV=1 Length=440 Score = 84.7 bits (208), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 65/220 (30%), Positives = 105/220 (48%), Gaps = 24/220 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FG V TGE+VAVK L D Q ++ E+ +L L+H +++ Sbjct 119 IGQGAFGPVY-----KAQMSTGEIVAVKVLATDS-KQGEKEFQTEVMLLGRLHHRNLVNL 172 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019 G C ++G+ L+ Y+ GSL +L +H + + A + G+ YLH Sbjct 173 IGYCAEKGQH--MLIYVYMSKGSLASHLYSEKHEPLSWDLRVYIALDVARGLEYLHDGAV 230 Query 1020 ---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA-PECLKE 1075 IHRD+ + N+LLD ++ DFGL++ +R F Y PE + Sbjct 231 PPVIHRDIKSSNILLDQSMRARVADFGLSREEMVDKHAANIR-----GTFGYLDPEYIST 285 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 F SDV+ FGV L+EL+ + ++P +EL+ +A Sbjct 286 RTFTKKSDVYGFGVLLFELI----AGRNPQQGLMELVELA 321 Score = 60.5 bits (145), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 63/258 (24%), Positives = 112/258 (43%), Gaps = 43/258 (17%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +KVL F L+ ++ H +L + G C +++++ Y+ G L Sbjct 138 VAVKVLATDSKQGEKEFQTEVMLLGRLHHRNLVNLIGYCAEKGQHMLIYVYMSKGSLASH 197 Query 699 LRRERGHVPMAW--KMVVAQQLASALSYLENKNL---VHGNVCGRNILLARLGLAEGTSP 753 L E+ H P++W ++ +A +A L YL + + +H ++ NILL + S Sbjct 198 LYSEK-HEPLSWDLRVYIALDVARGLEYLHDGAVPPVIHRDIKSSNILLDQ-------SM 249 Query 754 FIKLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGATLL 805 +++D G LSREE V++ +L PE + + + D +GFG L Sbjct 250 RARVADFG-----LSREEMVDKHAANIRGTFGYLDPEYIS--TRTFTKKSDVYGFGVLLF 302 Query 806 EICFDGEAP---------LQSRSPSEK---EHFYQRQ--HRLPEPSCPQLATLTSQCLTY 851 E+ G P L + + EK E + R ++A +C++ Sbjct 303 EL-IAGRNPQQGLMELVELAAMNAEEKVGWEEIVDSRLDGRYDLQEVNEVAAFAYKCISR 361 Query 852 EPTQRPSFRTILRDLTRL 869 P +RP+ R I++ LTR+ Sbjct 362 APRKRPNMRDIVQVLTRV 379 >sp|Q9SGP2|HSL1_ARATH Receptor-like protein kinase HSL1 OS=Arabidopsis thaliana OX=3702 GN=HSL1 PE=1 SV=1 Length=996 Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 69/217 (32%), Positives = 104/217 (48%), Gaps = 33/217 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-------KADCGPQ-------HRSGWKQEI 948 +G G GKV Y TN GE VAVK L DC P+ ++ E+ Sbjct 682 IGAGASGKV--YKVVLTN---GETVAVKRLWTGSVKETGDCDPEKGYKPGVQDEAFEAEV 736 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA------QLLL 1002 + L + H++I+K CC + K LV EY+P GSL D L G+ +++L Sbjct 737 ETLGKIRHKNIVKLWCCCSTRDCK--LLVYEYMPNGSLGDLLHSSKGGMLGWQTRFKIIL 794 Query 1003 FAQQICEGMAYLHAQHY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 A EG++YLH +HRD+ + N+L+D D ++ DFG+AKAV + + Sbjct 795 DA---AEGLSYLHHDSVPPIVHRDIKSNNILIDGDYGARVADFGVAKAVDLTGKAPKSMS 851 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 + APE + SD++SFGV + E++T Sbjct 852 VIAGSCGYIAPEYAYTLRVNEKSDIYSFGVVILEIVT 888 >sp|Q6P3R8|NEK5_HUMAN Serine/threonine-protein kinase Nek5 OS=Homo sapiens OX=9606 GN=NEK5 PE=1 SV=1 Length=708 Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 57/202 (28%), Positives = 99/202 (49%), Gaps = 14/202 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEH 958 I+ +G+G FGK Y + +K + + P Q + K+E+ +L + H + Sbjct 7 IKAIGQGAFGKA----YLAKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKHPN 62 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLH 1015 I+ + ++ G L +VMEY G L + R L Q+L + QI G+ ++H Sbjct 63 IVAFFNSFQENGR--LFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIH 120 Query 1016 AQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 + +HRD+ A+N+ L + +V K+GDFG+A+ + E R ++ +PE + Sbjct 121 DRKILHRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELART---CIGTPYYLSPEICQ 177 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + +D+WS G LYEL T Sbjct 178 NKPYNNKTDIWSLGCVLYELCT 199 Score = 45.8 bits (107), Expect = 0.003, Method: Compositional matrix adjust. Identities = 51/220 (23%), Positives = 90/220 (41%), Gaps = 34/220 (15%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQL 718 L+ ++ H ++ +V EY + G L + R+RG V + ++ Q+ Sbjct 54 LLEKMKHPNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRG-VLFSEDQILGWFVQI 112 Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI-- 776 + L ++ ++ ++H ++ +NI L++ G+ KL D G+ L+ + R Sbjct 113 SLGLKHIHDRKILHRDIKAQNIFLSKNGMV------AKLGDFGIAR-VLNNSMELARTCI 165 Query 777 ---PWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FDGEAPLQSRSPSEKEHFYQ 828 +L+PE + T D W G L E+C F+G Q + HF Sbjct 166 GTPYYLSPEICQNKPYNNKT--DIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHF-- 221 Query 829 RQHRLPEPSCP----QLATLTSQCLTYEPTQRPSFRTILR 864 P P +L +L SQ P RPS +IL+ Sbjct 222 ------APISPGFSRELHSLISQLFQVSPRDRPSINSILK 255 >sp|C0LGQ5|GSO1_ARATH LRR receptor-like serine/threonine-protein kinase GSO1 OS=Arabidopsis thaliana OX=3702 GN=GSO1 PE=1 SV=1 Length=1249 Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 79/282 (28%), Positives = 122/282 (43%), Gaps = 34/282 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G GKV Y + N GE VAVK + + +E+ L + H H++K Sbjct 957 IGSGGSGKV--YKAELEN---GETVAVKKILWKDDLMSNKSFSREVKTLGRIRHRHLVKL 1011 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---------PRHSIGLAQLLLFAQQICEGMAY 1013 G C + E L+ EY+ GS+ D+L + + L A + +G+ Y Sbjct 1012 MGYCSSKSEGLNLLIYEYMKNGSIWDWLHEDKPVLEKKKKLLDWEARLRIAVGLAQGVEY 1071 Query 1014 LH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-A 1069 LH +HRD+ + NVLLD++ +GDFGLAK + E + + + Y A Sbjct 1072 LHHDCVPPIVHRDIKSSNVLLDSNMEAHLGDFGLAKVLTENCDTNTDSNTWFACSYGYIA 1131 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKF-------LELIGIAQGQM 1119 PE K SDV+S G+ L E++T DS LE+ G A+ ++ Sbjct 1132 PEYAYSLKATEKSDVYSMGIVLMEIVTGKMPTDSVFGAEMDMVRWVETHLEVAGSARDKL 1191 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 +L L LP + C+V + C +T RP+ Sbjct 1192 IDPKLKPL------LPFEEDAACQVLEIALQCTKTSPQERPS 1227 Score = 35.0 bits (79), Expect = 5.9, Method: Compositional matrix adjust. Identities = 25/101 (25%), Positives = 48/101 (48%), Gaps = 12/101 (12%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEHGPLDVWLRR-----ERGHV 706 +F + ++ H HL + G C E N+++ EY+++G + WL E+ Sbjct 992 SFSREVKTLGRIRHRHLVKLMGYCSSKSEGLNLLIYEYMKNGSIWDWLHEDKPVLEKKKK 1051 Query 707 PMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILL 742 + W ++ +A LA + YL + +VH ++ N+LL Sbjct 1052 LLDWEARLRIAVGLAQGVEYLHHDCVPPIVHRDIKSSNVLL 1092 >sp|Q8VYT3|Y4052_ARATH Probable LRR receptor-like serine/threonine-protein kinase At4g30520 OS=Arabidopsis thaliana OX=3702 GN=At4g30520 PE=1 SV=1 Length=648 Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 66/198 (33%), Positives = 94/198 (47%), Gaps = 13/198 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V G G MVAVK LK G S ++ E++++ H+++++ Sbjct 309 LGAGGFGNVY-----RGKLGDGTMVAVKRLKDINGTSGDSQFRMELEMISLAVHKNLLRL 363 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ---H 1018 G C GE+ LV Y+P GS+ L + ++ A G+ YLH Q Sbjct 364 IGYCATSGER--LLVYPYMPNGSVASKLKSKPALDWNMRKRIAIGAARGLLYLHEQCDPK 421 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ A N+LLD +GDFGLAK + + G V APE L + Sbjct 422 IIHRDVKAANILLDECFEAVVGDFGLAKLLNHADSHVTTAVRG--TVGHIAPEYLSTGQS 479 Query 1079 YYASDVWSFGVTLYELLT 1096 +DV+ FG+ L EL+T Sbjct 480 SEKTDVFGFGILLLELIT 497 >sp|C0LGT5|Y5169_ARATH Probable LRR receptor-like serine/threonine-protein kinase At5g16900 OS=Arabidopsis thaliana OX=3702 GN=At5g16900 PE=1 SV=1 Length=866 Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 63/204 (31%), Positives = 105/204 (51%), Gaps = 16/204 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R +GEG FG V + ND E VAVK L ++ +K E+++L ++H +++ Sbjct 577 RVIGEGGFGVV---YHGYLNDS--EQVAVKVLSPSSSQGYKE-FKAEVELLLRVHHINLV 630 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHS---IGLAQLLLFAQQICEGMAYLHA 1016 G C++Q L L+ EY+ G L+ +L +H + L A + G+ YLH+ Sbjct 631 SLVGYCDEQAH--LALIYEYMANGDLKSHLSGKHGDCVLKWENRLSIAVETALGLEYLHS 688 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +HRD+ + N+LLD K+ DFGL+++ G E + +P + PE Sbjct 689 GCKPLMVHRDVKSMNILLDEHFQAKLADFGLSRSFSVGEESHVSTGVVGTPGYL-DPEYY 747 Query 1074 KEYKFYYASDVWSFGVTLYELLTH 1097 + Y+ SDV+SFG+ L E++T+ Sbjct 748 RTYRLTEKSDVYSFGIVLLEIITN 771 Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust. Identities = 63/240 (26%), Positives = 96/240 (40%), Gaps = 35/240 (15%) Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660 TN +E + G G G ++D + +V +KVL PS F Sbjct 572 TNNFERVIGEGGFGVVYHGYLNDSE------------QVAVKVLSPSSSQGYKEFKAEVE 619 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQL 718 L+ +V H +L + G C ++ EY+ +G L L + G + W ++ +A + Sbjct 620 LLLRVHHINLVSLVGYCDEQAHLALIYEYMANGDLKSHLSGKHGDCVLKWENRLSIAVET 679 Query 719 ASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER--- 772 A L YL + +VH +V NILL A KL+D G+ EE Sbjct 680 ALGLEYLHSGCKPLMVHRDVKSMNILLDEHFQA-------KLADFGLSRSFSVGEESHVS 732 Query 773 --VERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 V P +L PE L+ D + FG LLEI + Q+ +E H +R Sbjct 733 TGVVGTPGYLDPEYY--RTYRLTEKSDVYSFGIVLLEIITNQPVLEQA---NENRHIAER 787 >sp|Q9ZVP5|M3K18_ARATH Mitogen-activated protein kinase kinase kinase 18 OS=Arabidopsis thaliana OX=3702 GN=MAPKKK18 PE=1 SV=1 Length=339 Score = 83.2 bits (204), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 70/209 (33%), Positives = 106/209 (51%), Gaps = 29/209 (14%) Query 901 RDLGEGHFGKVSL-YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ-EIDILRTLYHEH 958 + LG G VS C++ +GE +AVK+ + HRS + Q E IL +L + Sbjct 7 KTLGRGSTATVSAATCHE-----SGETLAVKSAEF-----HRSEFLQREAKILSSLNSPY 56 Query 959 IIKYKGC------CEDQGE-KSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICE 1009 +I Y+GC + GE + L+MEY P G+L D ++ I A+++ + +QI Sbjct 57 VIGYRGCEITREPFHNNGEATTYSLLMEYAPYGTLTDVATKNGGFIDEARVVKYTRQILL 116 Query 1010 GMAYLHAQHYI-HRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFW 1067 G+ Y+H I H D+ NVL+ + KI DFG AK V PE E R +P F Sbjct 117 GLEYIHNSKGIAHCDIKGSNVLVGENGEAKIADFGCAKWVEPEITEPVR-----GTPAF- 170 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096 APE + + SD+W+ G T+ E++T Sbjct 171 MAPEAARGERQGKESDIWAVGCTVIEMVT 199 Score = 39.3 bits (90), Expect = 0.18, Method: Compositional matrix adjust. Identities = 47/214 (22%), Positives = 88/214 (41%), Gaps = 27/214 (13%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN-KNLVHGNVCGRNILLA 743 ++ EY +G L + G + A + +Q+ L Y+ N K + H ++ G N+L+ Sbjct 81 LLMEYAPYGTLTDVATKNGGFIDEARVVKYTRQILLGLEYIHNSKGIAHCDIKGSNVLVG 140 Query 744 RLGLAE----GTSPFI--KLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDK 797 G A+ G + ++ ++++P G A +APE G + D Sbjct 141 ENGEAKIADFGCAKWVEPEITEPVRGTPAF-----------MAPEAARGERQGKES--DI 187 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCP---QLATLTSQCLTYE 852 W G T++E+ + + + Y+ + LPE C Q +CL E Sbjct 188 WAVGCTVIEMVTGSQPWIGADFTDPVSVLYRVGYLGELPELPCSLTEQAKDFLGKCLKKE 247 Query 853 PTQRPSFRTILRD--LTRLQPHNLADVLTVNPDS 884 T+R + +L L +P + ++T +P S Sbjct 248 ATERWTASQLLNHPFLVNKEPELVTGLVTNSPTS 281 >sp|Q0GGW5|STK11_CHICK Serine/threonine-protein kinase STK11 OS=Gallus gallus OX=9031 GN=STK11 PE=2 SV=1 Length=440 Score = 84.3 bits (207), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 60/198 (30%), Positives = 97/198 (49%), Gaps = 6/198 (3%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG +GKV D + +K K P + K+EI +LR L H+++I+ Sbjct 55 LGEGSYGKVK-EMLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQL 113 Query 963 KGCCEDQGEKSLQLVMEYVPLG--SLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 ++ ++ + +VMEY G + D +P + Q + Q+ +G+ YLH+Q + Sbjct 114 VDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVFQAHGYFCQLIDGLEYLHSQGIV 173 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 H+D+ N+LL + +KI D G+A+A+ E R SP F PE + Sbjct 174 HKDIKPGNLLLTTNGTLKISDLGVAEALHPFAEDDTCRTSQGSPAFQ-PPEIANGLDTFS 232 Query 1080 -YASDVWSFGVTLYELLT 1096 + D+WS GVTLY + T Sbjct 233 GFKVDIWSAGVTLYNITT 250 Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust. Identities = 47/181 (26%), Positives = 75/181 (41%), Gaps = 21/181 (12%) Query 717 QLASALSYLENKNLVHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPGVGLGALS 768 QL L YL ++ +VH ++ N+LL + LG+AE PF + G+ Sbjct 159 QLIDGLEYLHSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEALHPFAEDDTCRTSQGS-- 216 Query 769 REERVERIPWLAPECLPGGANSLST-AMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHF 826 P P + G ++ S +D W G TL I G P + + + E+ Sbjct 217 --------PAFQPPEIANGLDTFSGFKVDIWSAGVTLYNIT-TGLYPFEGDNIYKLFENI 267 Query 827 YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 + +PE P L+ L L Y+P +R S + I + + H A+ L P SP Sbjct 268 GKGDFTIPEDCGPPLSDLLRGMLEYDPAKRFSIQQIRQHNWFRKKHAQAETLVPIPPSPE 327 Query 887 S 887 + Sbjct 328 T 328 >sp|P70032|PLK1_XENLA Serine/threonine-protein kinase PLK1 OS=Xenopus laevis OX=8355 GN=plk1 PE=1 SV=1 Length=598 Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 63/197 (32%), Positives = 96/197 (49%), Gaps = 12/197 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960 LG+G F K CY+ T+ + E+ A K + P + EI I R+L H H++ Sbjct 50 LGKGGFAK----CYEITDLESREVFAGKIVPKTMLLKPHQKDKMTMEIAIQRSLDHRHVV 105 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G ED + +V+E SL + + R ++ + + +Q G YLH+ Sbjct 106 GFHGFFEDND--FVYVVLELCRRRSLLELHKRRKAVTEPEARYYLKQTISGCQYLHSNRV 163 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRDL N+ L+++ VKIGDFGLA V E R + +P + APE L + Sbjct 164 IHRDLKLGNLFLNDEMEVKIGDFGLATKVEYDGE--RKKTLCGTPN-YIAPEVLGKKGHS 220 Query 1080 YASDVWSFGVTLYELLT 1096 + D+WS G +Y LL Sbjct 221 FEVDIWSIGCIMYTLLV 237 Score = 42.0 bits (97), Expect = 0.033, Method: Compositional matrix adjust. Identities = 47/211 (22%), Positives = 83/211 (39%), Gaps = 16/211 (8%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 ++ + H H+ HG +V E L + L + R V +Q Sbjct 94 AIQRSLDHRHVVGFHGFFEDNDFVYVVLELCRRRSL-LELHKRRKAVTEPEARYYLKQTI 152 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776 S YL + ++H R++ L L L + +K+ D G+ ER + + Sbjct 153 SGCQYLHSNRVIH-----RDLKLGNLFLNDEME--VKIGDFGLATKVEYDGERKKTLCGT 205 Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLP 834 ++APE L G S +D W G + + G+ P ++ E + ++ +P Sbjct 206 PNYIAPEVL--GKKGHSFEVDIWSIGCIMYTLLV-GKPPFETSCLKETYMRIKKNEYSIP 262 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + P A L + L +PT RP+ +L D Sbjct 263 KHINPVAAALIQKMLRSDPTSRPTIDDLLND 293 >sp|P93749|Y2197_ARATH Probable protein kinase At2g41970 OS=Arabidopsis thaliana OX=3702 GN=At2g41970 PE=2 SV=1 Length=365 Score = 83.6 bits (205), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 73/283 (26%), Positives = 127/283 (45%), Gaps = 25/283 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG +G+V +C GE VA+K L A + S + ++ ++ L H+H ++ Sbjct 79 IGEGSYGRV--FC----GKFKGEAVAIKKLDASSSEEPDSDFTSQLSVVSRLKHDHFVEL 132 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQLLLFAQQICEGMA 1012 G C + + L+ ++ GSL D L P + Q + A +G+ Sbjct 133 LGYCLEANNRI--LIYQFATKGSLHDVLHGRKGVQGAEPGPVLNWNQRVKIAYGAAKGLE 190 Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWY 1068 +LH + +HRD+ + NVLL +D + K+ DF L A + + R G ++ Sbjct 191 FLHEKVQPPIVHRDVRSSNVLLFDDFVAKMADFNLTNASSDTAARLHSTRVLGT--FGYH 248 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + SDV+SFGV L ELLT + P L+ A +++ ++ + Sbjct 249 APEYAMTGQITQKSDVYSFGVVLLELLTGRKPVDHTMPKGQQSLVTWATPRLSEDKVKQC 308 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 ++ P K ++ + C + EA FRP ++ L+ Sbjct 309 IDPKLNNDFPPKAVAKLAAVAALCVQYEADFRPNMTIVVKALQ 351 Score = 39.3 bits (90), Expect = 0.21, Method: Compositional matrix adjust. Identities = 62/271 (23%), Positives = 111/271 (41%), Gaps = 38/271 (14%) Query 630 GRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 G+ +G+ V +K LD S + + F S++S++ H H + G C+ I++ + Sbjct 90 GKFKGEA--VAIKKLDASSSEEPDSDFTSQLSVVSRLKHDHFVELLGYCLEANNRILIYQ 147 Query 689 YVEHGPL-DVWLRRE--RGHVP---MAW--KMVVAQQLASALSYLENK---NLVHGNVCG 737 + G L DV R+ +G P + W ++ +A A L +L K +VH +V Sbjct 148 FATKGSLHDVLHGRKGVQGAEPGPVLNWNQRVKIAYGAAKGLEFLHEKVQPPIVHRDVRS 207 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-ERIPWLAPECLPGGANSLSTAMD 796 N+LL +A+ L++ A RV + APE G ++ D Sbjct 208 SNVLLFDDFVAKMAD--FNLTNASSDTAARLHSTRVLGTFGYHAPEYAMTG--QITQKSD 263 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFY------------------QRQHRLPEPSC 838 + FG LLE+ G P+ P ++ + + P + Sbjct 264 VYSFGVVLLEL-LTGRKPVDHTMPKGQQSLVTWATPRLSEDKVKQCIDPKLNNDFPPKAV 322 Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 +LA + + C+ YE RP+ +++ L L Sbjct 323 AKLAAVAALCVQYEADFRPNMTIVVKALQPL 353 >sp|Q9M020|LRK63_ARATH Lectin-domain containing receptor kinase VI.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK63 PE=2 SV=1 Length=688 Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 67/213 (31%), Positives = 107/213 (50%), Gaps = 25/213 (12%) Query 897 LKKIRDLGEGHFGKV-SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---EIDILR 952 K+ R +G G FG V P++D +AVK + P G ++ EI+ L Sbjct 361 FKENRIVGTGGFGTVFRGNLSSPSSD----QIAVKKIT----PNSMQGVREFIAEIESLG 412 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHS---IGLAQLLLFAQQ 1006 L H++++ +G C+ + + L L+ +Y+P GSL L PR S + A+ Sbjct 413 RLRHKNLVNLQGWCKQKND--LLLIYDYIPNGSLDSLLYSRPRQSGVVLSWNARFKIAKG 470 Query 1007 ICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 I G+ YLH + IHRD+ NVL+++D ++GDFGLA+ G + G Sbjct 471 IASGLLYLHEEWEKVVIHRDIKPSNVLIEDDMNPRLGDFGLARLYERGSQSNTTVVVG-- 528 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 + + APE + K ASDV++FGV L E+++ Sbjct 529 TIGYMAPELARNGKSSSASDVFAFGVLLLEIVS 561 Score = 53.9 bits (128), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 62/262 (24%), Positives = 112/262 (43%), Gaps = 48/262 (18%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 ++ +K + P+ F + ++ H +L + G C + + +++ +Y+ +G LD Sbjct 387 QIAVKKITPNSMQGVREFIAEIESLGRLRHKNLVNLQGWCKQKNDLLLIYDYIPNGSLDS 446 Query 698 WL--RRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEG 750 L R + V ++W + +A+ +AS L YL K ++H ++ N+L + + Sbjct 447 LLYSRPRQSGVVLSWNARFKIAKGIASGLLYLHEEWEKVVIHRDIKPSNVL-----IEDD 501 Query 751 TSPFIKLSDPGVG----LGALSREE-RVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 +P +L D G+ G+ S V I ++APE G + S+A D + FG LL Sbjct 502 MNP--RLGDFGLARLYERGSQSNTTVVVGTIGYMAPELARNGKS--SSASDVFAFGVLLL 557 Query 806 EICFDGEAPLQSRSPSEKEHFY--------QRQHRLPEPSCPQLA------------TLT 845 EI + R P++ F+ + + P+L + Sbjct 558 EI-------VSGRRPTDSGTFFLADWVMELHARGEILHAVDPRLGFGYDGVEARLALVVG 610 Query 846 SQCLTYEPTQRPSFRTILRDLT 867 C PT RPS RT+LR L Sbjct 611 LLCCHQRPTSRPSMRTVLRYLN 632 >sp|P18161|SPLB_DICDI Dual specificity protein kinase splB OS=Dictyostelium discoideum OX=44689 GN=splB PE=2 SV=2 Length=1155 Score = 86.3 bits (212), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 81/283 (29%), Positives = 129/283 (46%), Gaps = 36/283 (13%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEH 958 I+ +GEG F +V + G VA+K LK Q + + +E+ L+ H++ Sbjct 856 IQKVGEGAFSEVWEGWWK------GIHVAIKKLKIIGDEEQFKERFIREVQNLKKGNHQN 909 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEGM 1011 I+ + G C K ++ EY+ GSL + L P+ +L A + G+ Sbjct 910 IVMFIGACY----KPACIITEYMAGGSLYNILHNPNSSTPKVKYSFPLVLKMATDMALGL 965 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAP 1070 +LH+ +HRDL ++N+LLD +KI DFGL++ EG + G W P Sbjct 966 LHLHSITIVHRDLTSQNILLDELGNIKISDFGLSREKSREGS--MTMTNGGICNPRWRPP 1023 Query 1071 ECLKEYKFYYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E K Y DV+ F + ++E+LT + P F +L G +Q V Sbjct 1024 ELTKNLGHYSEKVDVYCFSLVVWEILT----GEIP---FSDLDG-SQASAQVAY------ 1069 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 G R P P+ C E+ L+ CWE + + RP F ++ LK + Sbjct 1070 AGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKLKEI 1112 Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 62/229 (27%), Positives = 92/229 (40%), Gaps = 39/229 (17%) Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP-------MAWKMVVAQQL 718 +H ++ G C + ++TEY+ G L L P + KM A + Sbjct 906 NHQNIVMFIGACYKPA--CIITEYMAGGSLYNILHNPNSSTPKVKYSFPLVLKM--ATDM 961 Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE---- 774 A L +L + +VH ++ +NILL LG IK+SD G LSRE+ E Sbjct 962 ALGLLHLHSITIVHRDLTSQNILLDELG-------NIKISDFG-----LSREKSREGSMT 1009 Query 775 -------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP---LQSRSPSEKE 824 W PE L S +D + F + EI GE P L S + Sbjct 1010 MTNGGICNPRWRPPE-LTKNLGHYSEKVDVYCFSLVVWEI-LTGEIPFSDLDGSQASAQV 1067 Query 825 HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 + + +PE P+L L +QC +P RP F I+ L + +N Sbjct 1068 AYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKLKEISWNN 1116 >sp|Q8LKZ1|NORK_PEA Nodulation receptor kinase OS=Pisum sativum OX=3888 GN=NORK PE=1 SV=1 Length=924 Score = 85.9 bits (211), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 78/278 (28%), Positives = 130/278 (47%), Gaps = 28/278 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG V Y T D G+ VAVK +++ Q + E+++L + HE+++ Sbjct 601 IGEGGFGSV----YRGTLDD-GQEVAVK-VRSATSTQGTREFDNELNLLSAIQHENLVPL 654 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHA- 1016 G C + ++ L V ++ GSL D L R + L A G+AYLH Sbjct 655 LGYCNEYDQQIL--VYPFMSNGSLLDRLYGEPAKRKILDWPTRLSIALGAARGLAYLHTF 712 Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECL 1073 + IHRD+ + N+LLD+ K+ DFG +K P EG Y + G + + PE Sbjct 713 PGRSVIHRDVKSSNILLDHSMCAKVADFGFSKYAPQEGDSYVSLEVRGTAG--YLDPEYY 770 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSP-----PTKFLELIGIAQGQMTVLRLTELL 1128 K + SDV+SFGV L E++ S + P P L+ A+ + ++ E++ Sbjct 771 KTQQLSEKSDVFSFGVVLLEIV----SGREPLNIKRPRVEWSLVEWAKPYIRASKVDEIV 826 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + G + + V + C E +++RP +++ Sbjct 827 DPGIKGGYHAEALWRVVEVALQCLEPYSTYRPCMVDIV 864 Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 68/259 (26%), Positives = 102/259 (39%), Gaps = 30/259 (12%) Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 D GQE V +KV + F +L+S + H +L + G C + I+V ++ Sbjct 615 DDGQE--VAVKVRSATSTQGTREFDNELNLLSAIQHENLVPLLGYCNEYDQQILVYPFMS 672 Query 692 HGPLDVWLRRE---RGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARL 745 +G L L E R + ++ +A A L+YL ++++H +V NILL Sbjct 673 NGSLLDRLYGEPAKRKILDWPTRLSIALGAARGLAYLHTFPGRSVIHRDVKSSNILLDHS 732 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 A+ P G +S E R +L PE LS D + FG LL Sbjct 733 MCAKVADFGFSKYAPQEGDSYVSLEVR-GTAGYLDPEYYK--TQQLSEKSDVFSFGVVLL 789 Query 806 EICFDGEAPLQSRSPS------EKEHFYQRQHRLPEPSCP------------QLATLTSQ 847 EI G PL + P E Y R ++ E P ++ + Q Sbjct 790 EIV-SGREPLNIKRPRVEWSLVEWAKPYIRASKVDEIVDPGIKGGYHAEALWRVVEVALQ 848 Query 848 CLTYEPTQRPSFRTILRDL 866 CL T RP I+R+L Sbjct 849 CLEPYSTYRPCMVDIVREL 867 >sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens OX=9606 GN=RPS6KA1 PE=1 SV=2 Length=735 Score = 85.5 bits (210), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 64/219 (29%), Positives = 113/219 (52%), Gaps = 13/219 (6%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGP 938 V S +DP+ F + ++ LG+G FGKV L T +G + A+K LK A Sbjct 50 VKAGSEKADPSHF-----ELLKVLGQGSFGKVFL-VRKVTRPDSGHLYAMKVLKKATLKV 103 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA 998 + R K E DIL + H ++K + +G+ L L+++++ G L L + + Sbjct 104 RDRVRTKMERDILADVNHPFVVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTE 161 Query 999 Q-LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + + + ++ G+ +LH+ I+RDL N+LLD + +K+ DFGL+K E ++ + Sbjct 162 EDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKK 218 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 V + APE + +++D WS+GV ++E+LT Sbjct 219 AYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLT 257 Score = 60.1 bits (144), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 58/189 (31%), Positives = 86/189 (46%), Gaps = 23/189 (12%) Query 946 QEIDIL-RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA 1004 +EI+IL R H +II K +D K + LV E + G L D + R + F Sbjct 458 EEIEILLRYGQHPNIITLKDVYDDG--KHVYLVTELMRGGELLDKILRQKFFSEREASFV 515 Query 1005 -QQICEGMAYLHAQHYIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 I + + YLH+Q +HRDL N+L N ++I DFG AK + E Sbjct 516 LHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRA--------E 567 Query 1060 DG--DSPVF---WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LI 1112 +G +P + + APE LK + D+WS G+ LY +L + P+ E L Sbjct 568 NGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILT 627 Query 1113 GIAQGQMTV 1121 I G+ T+ Sbjct 628 RIGSGKFTL 636 >sp|Q9SY89|Y1661_ARATH Putative G-type lectin S-receptor-like serine/threonine-protein kinase At1g61610 OS=Arabidopsis thaliana OX=3702 GN=At1g61610 PE=3 SV=1 Length=842 Score = 85.9 bits (211), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 79/282 (28%), Positives = 125/282 (44%), Gaps = 28/282 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V N G +AVK L Q +K EI ++ L H ++++ Sbjct 531 LGQGGFGTVY-----KGNFSEGREIAVKRLSGK-SKQGLEEFKNEILLIAKLQHRNLVRL 584 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017 GCC + EK L+ EY+P SL +L + S+ + I G+ YLH Sbjct 585 LGCCIEDNEK--MLLYEYMPNKSLDRFLFDESKQGSLDWRKRWEVIGGIARGLLYLHRDS 642 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV------FWYA 1069 IHRDL A N+LLD + KI DFG+A+ + R+D + + + A Sbjct 643 RLKIIHRDLKASNILLDTEMNPKISDFGMARI-------FNYRQDHANTIRVVGTYGYMA 695 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE E F SDV+SFGV + E+++ + T LIG A + + E+++ Sbjct 696 PEYAMEGIFSEKSDVYSFGVLILEIVSGRKNVSFRGTDHGSLIGYAWHLWSQGKTKEMID 755 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + R H+ C + RP +++ +L++ Sbjct 756 PIVKDTRDVTEAMRCIHVGMLCTQDSVIHRPNMGSVLLMLES 797 Score = 42.0 bits (97), Expect = 0.044, Method: Compositional matrix adjust. Identities = 42/164 (26%), Positives = 71/164 (43%), Gaps = 20/164 (12%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F L++++ H +L + G C+ E +++ EY+ + LD +L E + W + Sbjct 566 FKNEILLIAKLQHRNLVRLLGCCIEDNEKMLLYEYMPNKSLDRFLFDESKQGSLDWRKRW 625 Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 V +A L YL + ++H ++ NILL T K+SD G+ R Sbjct 626 EVIGGIARGLLYLHRDSRLKIIHRDLKASNILL-------DTEMNPKISDFGMARIFNYR 678 Query 770 EERVERI------PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 ++ I ++APE G S D + FG +LEI Sbjct 679 QDHANTIRVVGTYGYMAPEYAMEGI--FSEKSDVYSFGVLILEI 720 >sp|Q9M1Z9|LRK58_ARATH Putative L-type lectin-domain containing receptor kinase V.8 OS=Arabidopsis thaliana OX=3702 GN=LECRK58 PE=3 SV=1 Length=626 Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 65/207 (31%), Positives = 106/207 (51%), Gaps = 18/207 (9%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 K+ + LG+G FG+V + T G+ +AVK D Q S + EI + L H Sbjct 303 FKEKQLLGKGGFGQV----FKGTLPGSNAEIAVKRTSHDS-RQGMSEFLAEISTIGRLRH 357 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMA 1012 ++++ G C + ++L LV ++ P GSL YL R+ + Q + + + Sbjct 358 PNLVRLLGYCRHK--ENLYLVYDFTPNGSLDKYLDRNENQERLTWEQRFKIIKDVASALL 415 Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068 +LH Q IHRD+ NVL+D++ +IGDFGLAK +G + R G F Y Sbjct 416 HLHQEWVQIIIHRDIKPANVLIDHEMNARIGDFGLAKLYDQGLDPQTSRVAG---TFGYI 472 Query 1069 APECLKEYKFYYASDVWSFGVTLYELL 1095 APE L+ + ++DV++FG+ + E++ Sbjct 473 APELLRTGRATTSTDVYAFGLVMLEVV 499 Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 47/178 (26%), Positives = 84/178 (47%), Gaps = 16/178 (9%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAW--K 711 F S + ++ H +L + G C R EN+ +V ++ +G LD +L R + W + Sbjct 345 FLAEISTIGRLRHPNLVRLLGYC-RHKENLYLVYDFTPNGSLDKYLDRNENQERLTWEQR 403 Query 712 MVVAQQLASALSYLEN---KNLVHGNVCGRNILLA-RLGLAEGTSPFIKLSDPGVGLGAL 767 + + +ASAL +L + ++H ++ N+L+ + G KL D G+ Sbjct 404 FKIIKDVASALLHLHQEWVQIIIHRDIKPANVLIDHEMNARIGDFGLAKLYDQGLD---- 459 Query 768 SREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + RV ++APE L G + ST D + FG +LE+ G ++ R+P +E Sbjct 460 PQTSRVAGTFGYIAPELLRTGRATTST--DVYAFGLVMLEVVC-GRRMIERRAPENEE 514 >sp|O75011|NAK1_SCHPO Serine/threonine-protein kinase nak1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=nak1 PE=1 SV=1 Length=652 Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 61/202 (30%), Positives = 99/202 (49%), Gaps = 13/202 (6%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH-- 956 K+ +G G +G V Y + T E VA+K L D S ++E+ +L L Sbjct 12 KLELVGRGSYGAV----YRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQSD 67 Query 957 -EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH 1015 E+IIKY G +L ++M+Y GS+R + I + L ++ + + ++H Sbjct 68 VENIIKYHGSY--LVGTNLWIIMDYCHGGSVRTLMEAGPISEPCISLILRETLQALKFIH 125 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 IHRD+ A N+L+ VK+ DFG+A E + R R +W APE +++ Sbjct 126 HAGIIHRDIKAANILVSMSGNVKLCDFGVAA---ELNINRRKRITFIGTPYWMAPEVIRD 182 Query 1076 YKFYYA-SDVWSFGVTLYELLT 1096 + Y +D+WS G+T YE+ T Sbjct 183 GQEYNVMADIWSLGITAYEIAT 204 Score = 41.2 bits (95), Expect = 0.067, Method: Compositional matrix adjust. Identities = 41/178 (23%), Positives = 77/178 (43%), Gaps = 18/178 (10%) Query 639 VVLKVL--DPSHHDIALAFYETASL--MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 V +K+L D +++ E A L + Q ++ HG + G ++ +Y G Sbjct 36 VAIKILNLDTDEDEVSDIQKEVAVLSELKQSDVENIIKYHGSYLVGTNLWIIMDYCHGGS 95 Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 + + E G + ++ ++ AL ++ + ++H ++ NIL++ G Sbjct 96 VRTLM--EAGPISEPCISLILRETLQALKFIHHAGIIHRDIKAANILVSMSG-------N 146 Query 755 IKLSDPGVGLG-ALSREERVERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 +KL D GV ++R +R+ I W+APE + G + D W G T EI Sbjct 147 VKLCDFGVAAELNINRRKRITFIGTPYWMAPEVIRDG-QEYNVMADIWSLGITAYEIA 203 >sp|O81832|Y4729_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At4g27290 OS=Arabidopsis thaliana OX=3702 GN=At4g27290 PE=3 SV=4 Length=783 Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 70/204 (34%), Positives = 100/204 (49%), Gaps = 22/204 (11%) Query 903 LGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG V +L C G+ VAVK L + Q +K EI ++ L H ++ Sbjct 471 LGQGGFGPVYKGTLAC--------GQEVAVKRL-SRTSRQGVEEFKNEIKLIAKLQHRNL 521 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015 +K G C D+ E+ L+ EY P SL ++ R + + + + I GM YLH Sbjct 522 VKILGYCVDEEER--MLIYEYQPNKSLDSFIFDKERRRELDWPKRVEIIKGIARGMLYLH 579 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 IHRDL A NVLLD+D KI DFGLA+ + G E + +PE Sbjct 580 EDSRLRIIHRDLKASNVLLDSDMNAKISDFGLARTLG-GDETEANTTRVVGTYGYMSPEY 638 Query 1073 LKEYKFYYASDVWSFGVTLYELLT 1096 + F SDV+SFGV + E+++ Sbjct 639 QIDGYFSLKSDVFSFGVLVLEIVS 662 Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust. Identities = 45/185 (24%), Positives = 83/185 (45%), Gaps = 22/185 (12%) Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 GQE V +K L + F L++++ H +L + G CV E +++ EY + Sbjct 487 GQE--VAVKRLSRTSRQGVEEFKNEIKLIAKLQHRNLVKILGYCVDEEERMLIYEYQPNK 544 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLA 748 LD ++ + + W ++ + + +A + YL + ++H ++ N+LL Sbjct 545 SLDSFIFDKERRRELDWPKRVEIIKGIARGMLYLHEDSRLRIIHRDLKASNVLL------ 598 Query 749 EGTSPFIKLSDPGVG--LGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGA 802 + K+SD G+ LG E R+ +++PE G SL + D + FG Sbjct 599 -DSDMNAKISDFGLARTLGGDETEANTTRVVGTYGYMSPEYQIDGYFSLKS--DVFSFGV 655 Query 803 TLLEI 807 +LEI Sbjct 656 LVLEI 660 >sp|Q5Z6X0|CIPKP_ORYSJ CBL-interacting protein kinase 25 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK25 PE=2 SV=1 Length=514 Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 67/205 (33%), Positives = 103/205 (50%), Gaps = 20/205 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG----WKQEIDILRTLYHEH 958 +GEG+F KV Y + TGE VA+K + D R G K+EI +++ L H + Sbjct 27 VGEGNFAKV----YLGRHRATGEEVAIKVM--DKEKLVRLGATELIKREIAVMQRLRHPN 80 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL------FAQQICEGMA 1012 +++ ++ + + +VMEYV G+L Y R G A L F QQ+ +A Sbjct 81 VVRIHEVMANK--RRICVVMEYVRGGALYRYFRRGPSGGAAGLREHEARRFFQQLVSAVA 138 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Y H++ HRD+ N+L+D +K+ DFGL+ ++ +P+F APE Sbjct 139 YCHSRGVFHRDIKLDNLLVDEQGNLKVADFGLSALADMERREAHLQTVCGTPLFL-APEV 197 Query 1073 LKEYKFYYA-SDVWSFGVTLYELLT 1096 K + A +DVW+ GV LY LLT Sbjct 198 FKRRGYDGAKADVWACGVVLYVLLT 222 Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 67/257 (26%), Positives = 102/257 (40%), Gaps = 41/257 (16%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYE----TASLMSQVSHTHLAFVHGVCVRGPENIM 685 GR R V +KV+D + L E ++M ++ H ++ +H V + Sbjct 38 GRHRATGEEVAIKVMDKEKL-VRLGATELIKREIAVMQRLRHPNVVRIHEVMANKRRICV 96 Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVA----QQLASALSYLENKNLVHGNVCGRNIL 741 V EYV G L + RR + A QQL SA++Y ++ + H ++ N+L Sbjct 97 VMEYVRGGALYRYFRRGPSGGAAGLREHEARRFFQQLVSAVAYCHSRGVFHRDIKLDNLL 156 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVER-------IP-WLAPECLPGGANSLST 793 + G +K++D GL AL+ ER E P +LAPE + Sbjct 157 VDEQG-------NLKVAD--FGLSALADMERREAHLQTVCGTPLFLAPEVFKRRGYDGAK 207 Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-------QRQHRLPEPSCPQLATLTS 846 A D W G L + L R P EH Q Q + P P LA L Sbjct 208 A-DVWACGVVLYVL-------LTGRKPFPDEHVSRLYRLIGQNQFQCPPSFSPDLARLVR 259 Query 847 QCLTYEPTQRPSFRTIL 863 + L +P +R + I+ Sbjct 260 RLLQPDPDRRITIPEIM 276 >sp|Q6CVA2|STE20_KLULA Serine/threonine-protein kinase STE20 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=STE20 PE=3 SV=1 Length=989 Score = 85.9 bits (211), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 55/208 (26%), Positives = 103/208 (50%), Gaps = 14/208 (7%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP+ +K +K +G+G G V Y GT VA+K + + P+ + E Sbjct 693 DPSKLYKNLIK----IGQGASGGV----YTAYELGTNASVAIKQMNLEKQPK-KELIVNE 743 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +++ H +I+ + +G+ L +VMEY+ GSL D + + Q+ +++ Sbjct 744 ILVMKGSKHNNIVNFIDSYLFRGD--LWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRET 801 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 +G+ +LH++ IHRD+ + N+LL + +K+ DFG + +E R +W Sbjct 802 LKGLQFLHSKGVIHRDIKSDNILLSMNGDIKLTDFGFCAQI---NEVNLKRTTMVGTPYW 858 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095 APE + ++ D+WS G+ + E++ Sbjct 859 MAPEVVSRKEYGPKVDIWSLGIMIIEMI 886 Score = 42.4 bits (98), Expect = 0.035, Method: Compositional matrix adjust. Identities = 55/229 (24%), Positives = 97/229 (42%), Gaps = 30/229 (13%) Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMV--VAQ 716 +M H ++ F+ RG + +V EY+E G L DV H + + V++ Sbjct 746 VMKGSKHNNIVNFIDSYLFRG-DLWVVMEYMEGGSLTDVVT-----HCILTEGQIGAVSR 799 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREER 772 + L +L +K ++H ++ NILL+ G IKL+D G + L R Sbjct 800 ETLKGLQFLHSKGVIHRDIKSDNILLSMNG-------DIKLTDFGFCAQINEVNLKRTTM 852 Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH- 831 V W+APE + +D W G ++E+ +GE P + +P + Sbjct 853 VGTPYWMAPEVV--SRKEYGPKVDIWSLGIMIIEM-IEGEPPYLNETPLRALYLIATNGT 909 Query 832 -RLPEPS--CPQLATLTSQCLTYEPTQRPSFRTILRD--LTRLQPHNLA 875 +L +P ++A + CL +P R + +L D +T + N + Sbjct 910 PKLKDPGNLSHKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTS 958 >sp|Q3ULB5|PAK6_MOUSE Serine/threonine-protein kinase PAK 6 OS=Mus musculus OX=10090 GN=Pak6 PE=2 SV=1 Length=682 Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 63/213 (30%), Positives = 105/213 (49%), Gaps = 24/213 (11%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP + Y+K +GEG G V L +G VAVK + Q R E Sbjct 403 DPRLLLDSYVK----IGEGSTGIVCLA----REKHSGRQVAVKMMDLRKQ-QRRELLFNE 453 Query 948 IDILRTLYHEHIIK-YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006 + I+R H ++++ YK GE+ L ++ME++ G+L D + + + Q+ + Sbjct 454 VVIMRDYQHLNVVEMYKSYLV--GEE-LWVLMEFLQGGALTDIISQVRLNEEQIATVCEA 510 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG----LAKAVPEGHEYYRVREDGD 1062 + + +AYLHAQ IHRD+ + ++LL D VK+ DFG ++K VP+ R+ Sbjct 511 VLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPK-------RKSLV 563 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 +W APE + + D+WS G+ + E++ Sbjct 564 GTPYWMAPEVISRSLYATEVDIWSLGIMVIEMV 596 Score = 47.4 bits (111), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 57/249 (23%), Positives = 106/249 (43%), Gaps = 34/249 (14%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 R++ +V +K++D + +M H ++ ++ + G E ++ E+ Sbjct 425 AREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHLNVVEMYKSYLVGEELWVLMEF 484 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 ++ G L + + R + V + + AL+YL + ++H ++ +ILL G Sbjct 485 LQGGALTDIISQVR--LNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDG--- 539 Query 750 GTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSL-STAMDKWGFGATL 804 +KLSD G + R+ V W+APE + + SL +T +D W G + Sbjct 540 ----RVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVI---SRSLYATEVDIWSLGIMV 592 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT----------LTSQCLTYEPT 854 +E+ DGE P S SP Q RL + + P+L + L EP Sbjct 593 IEMV-DGEPPYFSDSP------VQAMKRLRDSAPPKLKNSYKVSPVLRDFLDRMLVREPQ 645 Query 855 QRPSFRTIL 863 +R + + +L Sbjct 646 ERATAQELL 654 >sp|P62205|PLK1_XENTR Serine/threonine-protein kinase PLK1 OS=Xenopus tropicalis OX=8364 GN=plk1 PE=2 SV=1 Length=598 Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 73/267 (27%), Positives = 119/267 (45%), Gaps = 28/267 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960 LG+G F K CY+ T+ + E+ A K + P + EI I R+L H H++ Sbjct 50 LGKGGFAK----CYEITDLESREVFAGKIVPKTMLLKPHQKDKMTMEIAIQRSLDHRHVV 105 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G ED + +V+E SL + + R ++ + + +Q G YLH+ Sbjct 106 GFHGFFEDND--FVYVVLELCRRRSLLELHKRRKAVTEPEARYYLKQTILGCQYLHSNRV 163 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRDL N+ L+++ VKIGDFGLA V E R + +P + APE L + Sbjct 164 IHRDLKLGNLFLNDEMEVKIGDFGLATKVEYDGE--RKKTLCGTPN-YIAPEVLGKKGHS 220 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 + D+WS G +Y L L+G + + L+ T + + P Sbjct 221 FEVDIWSIGCIMYTL----------------LVGKPPFETSCLKETYMRIKKNEYSVPKH 264 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLI 1166 L++ +E + RPT ++L+ Sbjct 265 INPMATALIQKMLRSEPTSRPTIDDLL 291 Score = 39.7 bits (91), Expect = 0.17, Method: Compositional matrix adjust. Identities = 46/211 (22%), Positives = 81/211 (38%), Gaps = 16/211 (8%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 ++ + H H+ HG +V E L + L + R V +Q Sbjct 94 AIQRSLDHRHVVGFHGFFEDNDFVYVVLELCRRRSL-LELHKRRKAVTEPEARYYLKQTI 152 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776 YL + ++H R++ L L L + +K+ D G+ ER + + Sbjct 153 LGCQYLHSNRVIH-----RDLKLGNLFLNDEME--VKIGDFGLATKVEYDGERKKTLCGT 205 Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLP 834 ++APE L G S +D W G + + G+ P ++ E + ++ +P Sbjct 206 PNYIAPEVL--GKKGHSFEVDIWSIGCIMYTLLV-GKPPFETSCLKETYMRIKKNEYSVP 262 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + P L + L EPT RP+ +L D Sbjct 263 KHINPMATALIQKMLRSEPTSRPTIDDLLND 293 >sp|Q9P286|PAK5_HUMAN Serine/threonine-protein kinase PAK 5 OS=Homo sapiens OX=9606 GN=PAK5 PE=1 SV=1 Length=719 Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 63/223 (28%), Positives = 104/223 (47%), Gaps = 28/223 (13%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 L V+P P + YL +GEG G V + T TG+ VAVK K D Sbjct 438 LVVSPGDP--------REYLANFIKIGEGSTGIVCI----ATEKHTGKQVAVK--KMDLR 483 Query 938 PQHRSGWK-QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996 Q R E+ I+R +H++++ E L +VME++ G+L D + + Sbjct 484 KQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDE--LWVVMEFLEGGALTDIVTHTRMN 541 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG----LAKAVPEGH 1052 Q+ + ++YLH Q IHRD+ + ++LL +D +K+ DFG ++K VP+ Sbjct 542 EEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPK-- 599 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 R+ +W APE + + D+WS G+ + E++ Sbjct 600 -----RKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMI 637 Score = 51.2 bits (121), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 52/191 (27%), Positives = 81/191 (42%), Gaps = 24/191 (13%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-D 696 +V +K +D + +M H ++ ++ + G E +V E++E G L D Sbjct 474 QVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTD 533 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 + +A V + ALSYL N+ ++H ++ +ILL G IK Sbjct 534 IVTHTRMNEEQIA---TVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGR-------IK 583 Query 757 LSDPG----VGLGALSREERVERIPWLAPEC---LPGGANSLSTAMDKWGFGATLLEICF 809 LSD G V R+ V W+APE LP G T +D W G ++E+ Sbjct 584 LSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYG-----TEVDIWSLGIMVIEM-I 637 Query 810 DGEAPLQSRSP 820 DGE P + P Sbjct 638 DGEPPYFNEPP 648 >sp|C0LGG6|Y5189_ARATH Probable LRR receptor-like protein kinase At1g51890 OS=Arabidopsis thaliana OX=3702 GN=At1g51890 PE=1 SV=2 Length=876 Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 62/204 (30%), Positives = 103/204 (50%), Gaps = 17/204 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LG+G FG V D T VAVK L ++ +K E+++L ++H H++ Sbjct 574 RVLGKGGFGTVYHGNLDDT------QVAVKMLSHSSAQGYKE-FKAEVELLLRVHHRHLV 626 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQL---LLFAQQICEGMAYLHA 1016 G C+D +L L+ EY+ G LR+ + +HS+ + + A + +G+ YLH Sbjct 627 GLVGYCDDG--DNLALIYEYMEKGDLRENMSGKHSVNVLSWETRMQIAVEAAQGLEYLHN 684 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +HRD+ N+LL+ K+ DFGL+++ P E + + +P + PE Sbjct 685 GCRPPMVHRDVKPTNILLNERSQAKLADFGLSRSFPVDGESHVMTVVAGTPGY-LDPEYY 743 Query 1074 KEYKFYYASDVWSFGVTLYELLTH 1097 + SDV+SFGV L E++T+ Sbjct 744 RTNWLSEKSDVYSFGVVLLEIVTN 767 Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 61/219 (28%), Positives = 87/219 (40%), Gaps = 33/219 (15%) Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660 T +E L G G G +DD +V +K+L S F Sbjct 569 TKNFERVLGKGGFGTVYHGNLDDT-------------QVAVKMLSHSSAQGYKEFKAEVE 615 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQL 718 L+ +V H HL + G C G ++ EY+E G L + + ++W +M +A + Sbjct 616 LLLRVHHRHLVGLVGYCDDGDNLALIYEYMEKGDLRENMSGKHSVNVLSWETRMQIAVEA 675 Query 719 ASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVE 774 A L YL N +VH +V NILL A KL+D G+ + E V Sbjct 676 AQGLEYLHNGCRPPMVHRDVKPTNILLNERSQA-------KLADFGLSRSFPVDGESHVM 728 Query 775 RIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + +L PE N LS D + FG LLEI Sbjct 729 TVVAGTPGYLDPEYY--RTNWLSEKSDVYSFGVVLLEIV 765 >sp|Q9FLW0|Y5241_ARATH Probable receptor-like protein kinase At5g24010 OS=Arabidopsis thaliana OX=3702 GN=At5g24010 PE=1 SV=1 Length=824 Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 61/188 (32%), Positives = 93/188 (49%), Gaps = 14/188 (7%) Query 938 PQHRSG---WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994 P R G + EI IL + H H++ G CE+Q E + LV EY+ G L+ +L + Sbjct 521 PGSRQGLPEFLSEITILSKIRHRHLVSLVGYCEEQSE--MILVYEYMDKGPLKSHLYGST 578 Query 995 ---IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + Q L G+ YLH +Q IHRD+ + N+LLDN+ + K+ DFGL+++ Sbjct 579 NPPLSWKQRLEVCIGAARGLHYLHTGSSQGIIHRDIKSTNILLDNNYVAKVADFGLSRSG 638 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 P E + V + PE + + SDV+SFGV L+E+L C P Sbjct 639 PCIDETH-VSTGVKGSFGYLDPEYFRRQQLTDKSDVYSFGVVLFEVL--CARPAVDPLLV 695 Query 1109 LELIGIAQ 1116 E + +A+ Sbjct 696 REQVNLAE 703 Score = 47.4 bits (111), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 42/158 (27%), Positives = 71/158 (45%), Gaps = 9/158 (6%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK--M 712 F +++S++ H HL + G C E I+V EY++ GPL L + P++WK + Sbjct 530 FLSEITILSKIRHRHLVSLVGYCEEQSEMILVYEYMDKGPLKSHLYGST-NPPLSWKQRL 588 Query 713 VVAQQLASALSYL---ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 V A L YL ++ ++H ++ NILL +A+ + S P + +S Sbjct 589 EVCIGAARGLHYLHTGSSQGIIHRDIKSTNILLDNNYVAKVADFGLSRSGPCIDETHVST 648 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 + +L PE L+ D + FG L E+ Sbjct 649 GVK-GSFGYLDPEYFR--RQQLTDKSDVYSFGVVLFEV 683 >sp|Q9M8J5|M2K8_ARATH Mitogen-activated protein kinase kinase 8 OS=Arabidopsis thaliana OX=3702 GN=MKK8 PE=3 SV=2 Length=309 Score = 82.4 bits (202), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 67/217 (31%), Positives = 101/217 (47%), Gaps = 26/217 (12%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 F L +I LG G+ G V + + T E+ A+K +K + S +EI+ Sbjct 46 NTFSVANLDRISVLGSGNGGTV----FKVKDKTTSEIYALKKVKENWD----STSLREIE 97 Query 950 ILRTLYHEHIIKYKGCCED-QGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008 ILR + ++ K ++ GE S+ +M+Y+ LGSL + QL L ++Q+ Sbjct 98 ILRMVNSPYVAKCHDIFQNPSGEVSI--LMDYMDLGSLESL---RGVTEKQLALMSRQVL 152 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE---------GHEYYRVRE 1059 EG YLH +HRD+ N+L + VKI DFG++K V G Y E Sbjct 153 EGKNYLHEHKIVHRDIKPANLLRSSKEEVKIADFGVSKIVVRSLNKCNSFVGTFAYMSPE 212 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 DS E + YA D+WSFG+T+ E+L Sbjct 213 RLDSEADGVTEE---DKSNVYAGDIWSFGLTMLEILV 246 >sp|Q9C823|Y1523_ARATH C-type lectin receptor-like tyrosine-protein kinase At1g52310 OS=Arabidopsis thaliana OX=3702 GN=At1g52310 PE=2 SV=1 Length=552 Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 75/254 (30%), Positives = 120/254 (47%), Gaps = 15/254 (6%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 G VAVK LK Q + + EI LYH +++ KGCC D GE+ +V E++ Sbjct 290 GTKVAVKRLKRS-SFQRKKEFYSEIRRAAKLYHPNVVAIKGCCYDHGERF--IVYEFIAS 346 Query 984 GSLRDYL---PR--HSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDR 1035 G L +L PR S+ L A + +G+A+LH + +HRD+ A NVLLD + Sbjct 347 GPLDRWLHHVPRGGRSLDWNMRLNIATTLAQGIAFLHDKVKPQVVHRDIRASNVLLDEEF 406 Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 + GL+K VP R G + + APE + + SDV+SFGV L E++ Sbjct 407 GAHLMGVGLSKFVPWEVMQERTVMAGGTYGY-LAPEYVYRNELTTKSDVYSFGVLLLEIV 465 Query 1096 THCDSSQSPPTK--FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE-VYHLMKNCW 1152 + +Q+ + + + A + R E+L+ P+ C + V L+ +C Sbjct 466 SGRRPTQAVNSSVGWQSIFEWATPLVQANRWLEILDPVITCGLPEACVVQKVVDLVYSCT 525 Query 1153 ETEASFRPTFENLI 1166 + S RP +++ Sbjct 526 QNVPSMRPRMSHVV 539 Score = 57.8 bits (138), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 57/198 (29%), Positives = 88/198 (44%), Gaps = 26/198 (13%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L S FY +++ H ++ + G C E +V E++ GPLD Sbjct 292 KVAVKRLKRSSFQRKKEFYSEIRRAAKLYHPNVVAIKGCCYDHGERFIVYEFIASGPLDR 351 Query 698 WLRRE-RGHVPMAWKM--VVAQQLASALSYLENK---NLVHGNVCGRNILL-----ARLG 746 WL RG + W M +A LA +++L +K +VH ++ N+LL A L Sbjct 352 WLHHVPRGGRSLDWNMRLNIATTLAQGIAFLHDKVKPQVVHRDIRASNVLLDEEFGAHL- 410 Query 747 LAEGTSPFI---KLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 + G S F+ + + V G +LAPE + N L+T D + FG Sbjct 411 MGVGLSKFVPWEVMQERTVMAGGT--------YGYLAPEYVY--RNELTTKSDVYSFGVL 460 Query 804 LLEICFDGEAPLQSRSPS 821 LLEI G P Q+ + S Sbjct 461 LLEI-VSGRRPTQAVNSS 477 >sp|Q8S9L6|CRK29_ARATH Cysteine-rich receptor-like protein kinase 29 OS=Arabidopsis thaliana OX=3702 GN=CRK29 PE=2 SV=1 Length=679 Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 68/203 (33%), Positives = 97/203 (48%), Gaps = 16/203 (8%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +LG G FG V + G+ +AVK L + G Q + +K EI +L L H ++++ Sbjct 362 ELGRGGFGSVYKGVFPQ-----GQEIAVKRLSGNSG-QGDNEFKNEILLLAKLQHRNLVR 415 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 G C QGE+ L LV E++ SL ++ R + I G+ YLH Sbjct 416 LIGFCI-QGEERL-LVYEFIKNASLDQFIFDTEKRQLLDWVVRYKMIGGIARGLLYLHED 473 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECL 1073 IHRDL A N+LLD + KI DFGLAK G +R + APE Sbjct 474 SRFRIIHRDLKASNILLDQEMNPKIADFGLAKLFDSGQTMTHRFTSRIAGTYGYMAPEYA 533 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 +F +DV+SFGV + E++T Sbjct 534 MHGQFSVKTDVFSFGVLVIEIIT 556 Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust. Identities = 49/190 (26%), Positives = 86/190 (45%), Gaps = 28/190 (15%) Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 +GQE+ V K L + F L++++ H +L + G C++G E ++V E++++ Sbjct 378 QGQEIAV--KRLSGNSGQGDNEFKNEILLLAKLQHRNLVRLIGFCIQGEERLLVYEFIKN 435 Query 693 GPLDVWL----RRERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILL--- 742 LD ++ +R+ + +KM+ +A L YL + ++H ++ NILL Sbjct 436 ASLDQFIFDTEKRQLLDWVVRYKMIGG--IARGLLYLHEDSRFRIIHRDLKASNILLDQE 493 Query 743 -----ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDK 797 A GLA KL D G + ++APE G S+ T D Sbjct 494 MNPKIADFGLA-------KLFDSGQTMTHRFTSRIAGTYGYMAPEYAMHGQFSVKT--DV 544 Query 798 WGFGATLLEI 807 + FG ++EI Sbjct 545 FSFGVLVIEI 554 >sp|P24583|KPC1_YEAST Protein kinase C-like 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PKC1 PE=1 SV=3 Length=1151 Score = 85.9 bits (211), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 70/265 (26%), Positives = 117/265 (44%), Gaps = 28/265 (11%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK---------- 899 T++ Q + + +L++ L P + T + SP T ++ K+ Sbjct 763 TFQIEQDHASKEVLQETVSLAPTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKRRKVSLD 822 Query 900 ----IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH---RSGWKQEIDILR 952 ++ LG+G+FGKV L + T + A+K LK D Q+ S ++ L Sbjct 823 NFVLLKVLGKGNFGKVIL----SKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLL 878 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 +H C Q E + ME++ G L ++ + + + +A ++ + Sbjct 879 ATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALK 938 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVFWYAP 1070 Y H I+RDL N+LL + +KI D+GL K +Y R +P F AP Sbjct 939 YFHDNGVIYRDLKLENILLTPEGHIKIADYGLCK----DEMWYGNRTSTFCGTPEF-MAP 993 Query 1071 ECLKEYKFYYASDVWSFGVTLYELL 1095 E LKE ++ A D W+FGV LY++L Sbjct 994 EILKEQEYTKAVDWWAFGVLLYQML 1018 >sp|Q9WTK7|STK11_MOUSE Serine/threonine-protein kinase STK11 OS=Mus musculus OX=10090 GN=Stk11 PE=1 SV=1 Length=436 Score = 84.0 bits (206), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 59/198 (30%), Positives = 96/198 (48%), Gaps = 6/198 (3%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG +GKV D + +K K P + K+EI +LR L H ++I+ Sbjct 55 LGEGSYGKVK-EVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHRNVIQL 113 Query 963 KGCCEDQGEKSLQLVMEYVPLG--SLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 ++ ++ + +VMEY G + D +P + Q + +Q+ +G+ YLH+Q + Sbjct 114 VDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFRQLIDGLEYLHSQGIV 173 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 H+D+ N+LL + +KI D G+A+A+ R SP F PE + Sbjct 174 HKDIKPGNLLLTTNGTLKISDLGVAEALHPFAVDDTCRTSQGSPAFQ-PPEIANGLDTFS 232 Query 1080 -YASDVWSFGVTLYELLT 1096 + D+WS GVTLY + T Sbjct 233 GFKVDIWSAGVTLYNITT 250 Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 56/210 (27%), Positives = 87/210 (41%), Gaps = 15/210 (7%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 MV EY G ++ P+ +QL L YL ++ +VH ++ N+LL Sbjct 127 MVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFRQLIDGLEYLHSQGIVHKDIKPGNLLLT- 185 Query 745 LGLAEGTSPFIKLSDPGVGLG----ALSREERVER-IPWLAPECLPGGANSLST-AMDKW 798 T+ +K+SD GV A+ R + P P + G ++ S +D W Sbjct 186 ------TNGTLKISDLGVAEALHPFAVDDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIW 239 Query 799 GFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857 G TL I G P + + + E+ + +P P L+ L L YEP +R Sbjct 240 SAGVTLYNIT-TGLYPFEGDNIYKLFENIGRGDFTIPCDCGPPLSDLLRGMLEYEPAKRF 298 Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 S R I + + H LA+ L P SP + Sbjct 299 SIRQIRQHSWFRKKHPLAEALVPIPPSPDT 328 >sp|Q9LFG1|Y3359_ARATH Putative leucine-rich repeat receptor-like serine/threonine-protein kinase At3g53590 OS=Arabidopsis thaliana OX=3702 GN=At3g53590 PE=1 SV=2 Length=937 Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 82/262 (31%), Positives = 120/262 (46%), Gaps = 49/262 (19%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV-FHKRYLKKIRDLGEGHFGKVS 912 T++ FRTI R++ ++ + ++ SD T F L +G G +GKV Sbjct 584 TKKRVFRTISREIKGVKKFSFVEL---------SDATNGFDSSTL-----IGRGSYGKV- 628 Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972 Y E VA+K + Q + EID+L L+H +++ G D GE+ Sbjct 629 ---YKGILSNKTE-VAIKR-GEETSLQSEKEFLNEIDLLSRLHHRNLVSLIGYSSDIGEQ 683 Query 973 SLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI------CEGMAYLHAQH---YIHRD 1023 LV EY+P G++RD+L S A L F+ + +G+ YLH + IHRD Sbjct 684 --MLVYEYMPNGNVRDWL---SANAADTLSFSMRSHVALGSAKGILYLHTEANPPVIHRD 738 Query 1024 LAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD----SPVF-----WYAPECLK 1074 + N+LLD K+ DFGL++ P E DG+ S V + PE Sbjct 739 IKTSNILLDCQLHAKVADFGLSRLAPAFGE-----GDGEPAHVSTVVRGTPGYLDPEYFM 793 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + SDV+SFGV L ELLT Sbjct 794 TQQLTVRSDVYSFGVVLLELLT 815 Score = 34.3 bits (77), Expect = 8.8, Method: Compositional matrix adjust. Identities = 57/237 (24%), Positives = 92/237 (39%), Gaps = 33/237 (14%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMV 713 F L+S++ H +L + G E ++V EY+ +G + WL + + + Sbjct 655 FLNEIDLLSRLHHRNLVSLIGYSSDIGEQMLVYEYMPNGNVRDWLSANAADTLSFSMRSH 714 Query 714 VAQQLASALSYLE---NKNLVHGNVCGRNILL--------ARLGLAEGTSPFIKLSDPGV 762 VA A + YL N ++H ++ NILL A GL+ F G Sbjct 715 VALGSAKGILYLHTEANPPVIHRDIKTSNILLDCQLHAKVADFGLSRLAPAF------GE 768 Query 763 GLGALSREERVER-IP-WLAPECLPGGANSLSTAMDKWGFGATLLEIC------FDGEAP 814 G G + V R P +L PE L+ D + FG LLE+ F+G Sbjct 769 GDGEPAHVSTVVRGTPGYLDPEYF--MTQQLTVRSDVYSFGVVLLELLTGMHPFFEGTHI 826 Query 815 L-QSRSPSEKEHFY----QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 + + R+ +E R + +LA L C P RP ++++L Sbjct 827 IREVRTANECGTVLSVADSRMGQCSPDKVKKLAELALWCCEDRPETRPPMSKVVKEL 883 >sp|Q5JK68|CDKC2_ORYSJ Cyclin-dependent kinase C-2 OS=Oryza sativa subsp. japonica OX=39947 GN=CDKC-2 PE=2 SV=1 Length=513 Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 64/223 (29%), Positives = 106/223 (48%), Gaps = 34/223 (15%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILR 952 +K+ +GEG +G+V + TN E+VA+K ++ D R G+ +EI IL+ Sbjct 25 FEKLEQIGEGTYGQVYMAKETETN----EIVALKKIRMD---NEREGFPITAIREIKILK 77 Query 953 TLYHEHIIKYKGCC-------EDQGEK--------SLQLVMEYVP--LGSLRDYLPRHSI 995 L+H+++I+ K ++QG+ S+ +V EY+ L L D P Sbjct 78 KLHHQNVIQLKEIVTSPGPERDEQGKPIEGNKYKGSIYMVFEYMDHDLTGLAD-RPGMRF 136 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + Q+ + +Q+ G+ Y H +HRD+ N+L+DN+ +K+ DFGLA++ H Sbjct 137 TVPQIKCYMRQLLTGLHYCHVNQVLHRDIKGSNLLIDNEGNLKLADFGLARSFSSDHNGN 196 Query 1056 RVREDGDSPVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096 WY P L ++ A D+WS G ELL Sbjct 197 LTNR---VITLWYRPPELLLGSTRYGPAVDMWSVGCIFAELLN 236 >sp|Q0VD22|STK33_BOVIN Serine/threonine-protein kinase 33 OS=Bos taurus OX=9913 GN=STK33 PE=2 SV=1 Length=486 Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 67/225 (30%), Positives = 104/225 (46%), Gaps = 22/225 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LG+G FG V + D + + V KA G ++E+DIL+++ HEHII Sbjct 120 RILGQGSFGMV-IEAIDKERETKWAIKKVNKEKA--GSSAVKLLEREVDILKSVKHEHII 176 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019 + E K + LVME G L++ L R + Q + +AYLH + Sbjct 177 HLEQVFETP--KKMYLVMELCEDGELKEILERKGHFSENETRWIIQSLASAIAYLHNKDI 234 Query 1020 IHRDLAARNVLLD------NDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 +HRDL N+++ N+ + +K+ DFGLA G ++ +P++ AP Sbjct 235 VHRDLKLENIMVKSSFIDANNEMNLNIKVTDFGLA-VKKHGRSEVMLQTTCGTPIY-MAP 292 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSS---QSPPTKFLELI 1112 E + + + D+WS GV +Y LL C + S K ELI Sbjct 293 EVINAHDYSQQCDIWSIGVIMYILL--CGKAPFMASSEEKLFELI 335 Score = 56.2 bits (134), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 54/247 (22%), Positives = 109/247 (44%), Gaps = 23/247 (9%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 ++ V H H+ + V + +V E E G L L R +GH + Q LAS Sbjct 166 ILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILER-KGHFSENETRWIIQSLAS 224 Query 721 ALSYLENKNLVHGNVCGRNILLAR--LGLAEGTSPFIKLSDPGVGLGALSREERVERIP- 777 A++YL NK++VH ++ NI++ + + IK++D G+ + R E + + Sbjct 225 AIAYLHNKDIVHRDLKLENIMVKSSFIDANNEMNLNIKVTDFGLAVKKHGRSEVMLQTTC 284 Query 778 ----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---- 829 ++APE + A+ S D W G ++ I G+AP + S + ++ Sbjct 285 GTPIYMAPEVI--NAHDYSQQCDIWSIGV-IMYILLCGKAPFMASSEEKLFELIKKGELH 341 Query 830 -QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD-------LTRLQPHNLADVLTVN 881 ++ + ++ Q + +P R + + +L + ++ +P N+ +++ Sbjct 342 FKNSIWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNTVSSARPTNVLEMMKEW 401 Query 882 PDSPASD 888 ++P SD Sbjct 402 KNNPESD 408 >sp|Q63531|KS6A1_RAT Ribosomal protein S6 kinase alpha-1 OS=Rattus norvegicus OX=10116 GN=Rps6ka1 PE=1 SV=1 Length=735 Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 64/219 (29%), Positives = 112/219 (51%), Gaps = 13/219 (6%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGP 938 V S +DP+ F + ++ LG+G FGKV L T G + A+K LK A Sbjct 50 VKAGSEKADPSHF-----ELLKVLGQGSFGKVFL-VRKVTRPDNGHLYAMKVLKKATLKV 103 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA 998 + R K E DIL + H ++K + +G+ L L+++++ G L L + + Sbjct 104 RDRVRTKMERDILADVNHPFVVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTE 161 Query 999 Q-LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + + + ++ G+ +LH+ I+RDL N+LLD + +K+ DFGL+K E ++ + Sbjct 162 EDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKK 218 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 V + APE + +++D WS+GV ++E+LT Sbjct 219 AYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLMFEMLT 257 Score = 62.0 bits (149), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 61/191 (32%), Positives = 90/191 (47%), Gaps = 27/191 (14%) Query 946 QEIDIL-RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLL 1001 +EI+IL R H +II K +D K + LV E + G L D + R S A + Sbjct 458 EEIEILLRYGQHPNIITLKDVYDDS--KHVYLVTELMRGGELLDKILRQKFFSEREASFV 515 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRV 1057 L+ I + + YLH+Q +HRDL N+L N ++I DFG AK + Sbjct 516 LYT--ISKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRA------- 566 Query 1058 REDG--DSPVF---WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE-- 1110 E+G +P + + APE LK + D+WS GV LY +L + P+ E Sbjct 567 -ENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGYTPFANGPSDTPEEI 625 Query 1111 LIGIAQGQMTV 1121 L I+ G+ T+ Sbjct 626 LTRISSGKFTL 636 >sp|O22187|Y2232_ARATH Probable receptor-like protein kinase At2g23200 OS=Arabidopsis thaliana OX=3702 GN=At2g23200 PE=3 SV=1 Length=834 Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 66/202 (33%), Positives = 99/202 (49%), Gaps = 21/202 (10%) Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G FG Y Y DGT A+K K G Q ++ EI +L + H H++ Sbjct 494 IGKGGFG----YVYKAILPDGTK--AAIKRGKTGSG-QGILEFQTEIQVLSRIRHRHLVS 546 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQ- 1017 G CE+ E + LV E++ G+L+++L S+ Q L G+ YLH+ Sbjct 547 LTGYCEENSE--MILVYEFMEKGTLKEHLYGSNLPSLTWKQRLEICIGAARGLDYLHSSG 604 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECL 1073 IHRD+ + N+LLD + K+ DFGL+K + + G F Y PE L Sbjct 605 SEGAIIHRDVKSTNILLDEHNIAKVADFGLSKIHNQDESNISINIKG---TFGYLDPEYL 661 Query 1074 KEYKFYYASDVWSFGVTLYELL 1095 + +K SDV++FGV L E+L Sbjct 662 QTHKLTEKSDVYAFGVVLLEVL 683 Score = 54.7 bits (130), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 61/243 (25%), Positives = 99/243 (41%), Gaps = 40/243 (16%) Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP-MAWK 711 L F ++S++ H HL + G C E I+V E++E G L L ++P + WK Sbjct 527 LEFQTEIQVLSRIRHRHLVSLTGYCEENSEMILVYEFMEKGTLKEHLY--GSNLPSLTWK 584 Query 712 --MVVAQQLASALSYLENKN----LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 + + A L YL + ++H +V NILL +A K++D G+ Sbjct 585 QRLEICIGAARGLDYLHSSGSEGAIIHRDVKSTNILLDEHNIA-------KVADFGLSKI 637 Query 766 ALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF-----DGEAPL 815 E + +L PE L + L+ D + FG LLE+ F D P Sbjct 638 HNQDESNISINIKGTFGYLDPEYLQ--THKLTEKSDVYAFGVVLLEVLFARPAIDPYLPH 695 Query 816 QSRSPSEKEHFYQRQHRLPE------------PSCPQLATLTSQCLTYEPTQRPSFRTIL 863 + + SE F + + + E S + + +CL +RPS R ++ Sbjct 696 EEVNLSEWVMFCKSKGTIDEILDPSLIGQIETNSLKKFMEIAEKCLKEYGDERPSMRDVI 755 Query 864 RDL 866 DL Sbjct 756 WDL 758 >sp|Q9SXB5|Y1135_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g11303 OS=Arabidopsis thaliana OX=3702 GN=At1g11303 PE=3 SV=1 Length=820 Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 86/282 (30%), Positives = 124/282 (44%), Gaps = 34/282 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG P G G+ +AVK L G Q E+ ++ L H ++ Sbjct 515 LGQGGFG--------PVYKGMLLEGQEIAVKRLSQASG-QGLEELVTEVVVISKLQHRNL 565 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLF--AQQICEGMAYLH 1015 +K GCC E+ LV E++P SL Y+ PR + L F IC G+ YLH Sbjct 566 VKLFGCCIAGEER--MLVYEFMPKKSLDFYIFDPREAKLLDWNTRFEIINGICRGLLYLH 623 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 IHRDL A N+LLD + + KI DFGLA+ P + R + + APE Sbjct 624 RDSRLRIIHRDLKASNILLDENLIPKISDFGLARIFPGNEDEANTRRVVGT-YGYMAPEY 682 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI---GIAQGQMTVLRLTELLE 1129 F SDV+S GV L E+++ +S S + I G G + +L E Sbjct 683 AMGGLFSEKSDVFSLGVILLEIISGRRNSHSTLLAHVWSIWNEGEINGMVDPEIFDQLFE 742 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + R KC H+ C + A+ RP+ + +L + Sbjct 743 KEIR-----KC----VHIALLCVQDAANDRPSVSTVCMMLSS 775 Score = 41.6 bits (96), Expect = 0.053, Method: Compositional matrix adjust. Identities = 41/158 (26%), Positives = 69/158 (44%), Gaps = 20/158 (13%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQL 718 ++S++ H +L + G C+ G E ++V E++ LD ++ R + W + + + Sbjct 556 VISKLQHRNLVKLFGCCIAGEERMLVYEFMPKKSLDFYIFDPREAKLLDWNTRFEIINGI 615 Query 719 ASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERV 773 L YL + ++H ++ NIL L E P K+SD G+ E Sbjct 616 CRGLLYLHRDSRLRIIHRDLKASNIL-----LDENLIP--KISDFGLARIFPGNEDEANT 668 Query 774 ERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 R+ ++APE GG S D + G LLEI Sbjct 669 RRVVGTYGYMAPEYAMGGL--FSEKSDVFSLGVILLEI 704 >sp|P43294|MHK_ARATH Serine/threonine-protein kinase MHK OS=Arabidopsis thaliana OX=3702 GN=MHK PE=2 SV=2 Length=443 Score = 84.0 bits (206), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 70/211 (33%), Positives = 96/211 (45%), Gaps = 21/211 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 VF K + +LG+G G V Y N T E+VAVK +K +E+ Sbjct 5 VVFVMCRYKILEELGDGTCGSV----YKAVNLETYEVVAVKKMKRKFYYWEECVNLREVK 60 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQIC 1008 LR L H HIIK K + E L + E + R ++ F Q+ Sbjct 61 ALRKLNHPHIIKLKEIVREHNE--LFFIFECMDHNLYHIMKERERPFSEGEIRSFMSQML 118 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV---PEGHEYYRVREDGDSPV 1065 +G+A++H Y HRDL N+L+ N+ ++KI DFGLA+ V P EY R Sbjct 119 QGLAHMHKNGYFHRDLKPENLLVTNN-ILKIADFGLAREVASMPPYTEYVSTR------- 170 Query 1066 FWY-APECLKEYKFYY-ASDVWSFGVTLYEL 1094 WY APE L + Y A D+W+ G L EL Sbjct 171 -WYRAPEVLLQSSLYTPAVDMWAVGAILAEL 200 >sp|Q6DE87|CHK1_XENLA Serine/threonine-protein kinase Chk1 OS=Xenopus laevis OX=8355 GN=chek1 PE=1 SV=2 Length=474 Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 73/204 (36%), Positives = 103/204 (50%), Gaps = 21/204 (10%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK----ADCGPQHRSGWKQEIDILRTLY 955 ++ LGEG +G+V L N T E VAVK + ADC P++ K+EI I R L Sbjct 12 VQTLGEGAYGEVQL----AVNRKTEEAVAVKIVDMTRAADC-PEN---IKKEICINRMLS 63 Query 956 HEHIIKYKGCCEDQGEKSLQ-LVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAY 1013 H +I+++ G + E ++Q L +EY G L D + P + F QQ+ G+ Y Sbjct 64 HTNIVRFYG---HRREGNIQYLFLEYCRGGELFDRIEPDVGMPEQDAQKFFQQLIAGVEY 120 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPEC 1072 LH+ HRD+ N+LLD +KI DFGLA G E + G P + APE Sbjct 121 LHSIGITHRDIKPENLLLDERDQLKISDFGLATVFRHNGKERLLNKMCGTLP--YVAPEL 178 Query 1073 LKEYKFYYA-SDVWSFGVTLYELL 1095 +K F+ DVWS G+ L +L Sbjct 179 IKSRAFHADPVDVWSCGIVLTAML 202 Score = 36.6 bits (83), Expect = 1.7, Method: Compositional matrix adjust. Identities = 71/295 (24%), Positives = 119/295 (40%), Gaps = 36/295 (12%) Query 632 DRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 +R E V +K++D + D + + +SHT++ +G G + EY Sbjct 28 NRKTEEAVAVKIVDMTRAADCPENIKKEICINRMLSHTNIVRFYGHRREGNIQYLFLEYC 87 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L + + G +P QQL + + YL + + H ++ N+LL Sbjct 88 RGGELFDRIEPDVG-MPEQDAQKFFQQLIAGVEYLHSIGITHRDIKPENLLL-------D 139 Query 751 TSPFIKLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSLSTAMDKWGFGA 802 +K+SD GL + R ER +P++APE + A + +D W G Sbjct 140 ERDQLKISD--FGLATVFRHNGKERLLNKMCGTLPYVAPELIKSRAFH-ADPVDVWSCGI 196 Query 803 TLLEICFDGEAPLQSRSPSEKEH--FYQRQHRL---PEPSCPQLATLTSQCLTYEPTQRP 857 L + GE P + +E+ + ++ H L + S LA L + LT P R Sbjct 197 VLTAM-LAGELPWDQPNEVCQEYCDWKEKNHYLTPWKKISATPLA-LLCKMLTENPQSRI 254 Query 858 SFRTILRD--LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR-DLGEGHFG 909 + I +D T + L ++ S SD +V K+IR D+ HF Sbjct 255 TIPDIKKDRWFTEIIKKGLKRSRVISGGS--SDSSVL----CKQIRSDIDISHFS 303 >sp|Q66HE5|NUAK2_RAT NUAK family SNF1-like kinase 2 OS=Rattus norvegicus OX=10116 GN=Nuak2 PE=1 SV=1 Length=630 Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 71/233 (30%), Positives = 109/233 (47%), Gaps = 22/233 (9%) Query 874 LADVLTVNPDSPASDPTV---FHKRYLKK----IRDLGEGHFGKVSLYCYDPTNDGTGEM 926 LAD L +P V HK L+ + LG+G +GKV + +G + Sbjct 27 LADRLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVK-----KARESSGRL 81 Query 927 VAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 VA+K+++ D Q ++EI+I+ +L H HII E+ + + +VMEY G Sbjct 82 VAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVFENSSK--IVIVMEYASRG 139 Query 985 SLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 L DY+ R + F +QI + Y H +HRDL N+LLD +KI DFG Sbjct 140 DLYDYISERPRLNERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDASGNIKIADFG 199 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELL 1095 L+ H+ ++ SP++ +PE + + D WS GV LY L+ Sbjct 200 LSNLY---HKGKFLQTFCGSPLY-ASPEIVNGKPYVGPEVDSWSLGVLLYILV 248 Score = 41.6 bits (96), Expect = 0.051, Method: Compositional matrix adjust. Identities = 42/159 (26%), Positives = 66/159 (42%), Gaps = 15/159 (9%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 +MS ++H H+ +H V + ++V EY G L ++ ER + +Q+ S Sbjct 107 IMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYI-SERPRLNERDARHFFRQIVS 165 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---- 776 AL Y +VH ++ NILL G IK++D GL L + + + Sbjct 166 ALHYCHQNGIVHRDLKLENILLDASG-------NIKIAD--FGLSNLYHKGKFLQTFCGS 216 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 P A + G + +D W G LL I G P Sbjct 217 PLYASPEIVNGKPYVGPEVDSWSLG-VLLYILVHGTMPF 254 >sp|Q5JLD8|CIPK8_ORYSJ CBL-interacting protein kinase 8 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK8 PE=2 SV=1 Length=446 Score = 84.0 bits (206), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 62/200 (31%), Positives = 102/200 (51%), Gaps = 13/200 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG--WKQEIDILRTLYHEH 958 R +GEG F KV N +GE VA+K + +H+ K+EI I++ + H + Sbjct 17 RTIGEGTFAKVKF----AQNTESGESVAMKVVDRSSILKHKMADQIKREISIMKLVRHPN 72 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQ 1017 +++ + K + +++E++ G L D + RH + A + QQ+ +G+ + H++ Sbjct 73 VVRLHEVLASR--KKIFIILEFITGGELFDKIIRHGRLNEADARRYFQQLIDGVDFCHSK 130 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 HRDL N+LLD+ +KI DFGL+ +G +R +P + APE L Sbjct 131 GVYHRDLKPENLLLDSQGNLKISDFGLSAWPAQGGAL--LRTTCGTPNY-VAPEVLSHKG 187 Query 1078 FYYA-SDVWSFGVTLYELLT 1096 + A +D WS GV LY LL Sbjct 188 YDGALADTWSCGVILYVLLA 207 Score = 36.2 bits (82), Expect = 2.1, Method: Compositional matrix adjust. Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 20/175 (11%) Query 639 VVLKVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +KV+D S H +A S+M V H ++ +H V + ++ E++ G L Sbjct 39 VAMKVVDRSSILKHKMADQIKREISIMKLVRHPNVVRLHEVLASRKKIFIILEFITGGEL 98 Query 696 -DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 D +R R + A + QQL + + +K + H ++ N+LL G Sbjct 99 FDKIIRHGRLNEADARRYF--QQLIDGVDFCHSKGVYHRDLKPENLLLDSQG-------N 149 Query 755 IKLSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 +K+SD G+ GAL R ++APE L + A D W G L Sbjct 150 LKISDFGLSAWPAQGGALLRTT-CGTPNYVAPEVLSHKGYDGALA-DTWSCGVIL 202 >sp|Q5R8Z4|PAK6_PONAB Serine/threonine-protein kinase PAK 6 OS=Pongo abelii OX=9601 GN=PAK6 PE=2 SV=1 Length=681 Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 63/213 (30%), Positives = 105/213 (49%), Gaps = 24/213 (11%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP + Y+K +GEG G V L +G VAVK + Q R E Sbjct 402 DPRLLLDSYVK----IGEGSTGIVCLA----REKHSGRQVAVKMMDLRKQ-QRRELLFNE 452 Query 948 IDILRTLYHEHIIK-YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006 + I+R H ++++ YK GE+ L ++ME++ G+L D + + + Q+ + Sbjct 453 VVIMRDYQHFNVVEMYKSYLV--GEE-LWVLMEFLQGGALTDIVSQVRLNEEQIATVCEA 509 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG----LAKAVPEGHEYYRVREDGD 1062 + + +AYLHAQ IHRD+ + ++LL D VK+ DFG ++K VP+ R+ Sbjct 510 VLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPK-------RKSLV 562 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 +W APE + + D+WS G+ + E++ Sbjct 563 GTPYWMAPEVISRSLYATEVDIWSLGIMVIEMV 595 Score = 47.4 bits (111), Expect = 0.001, Method: Compositional matrix adjust. Identities = 56/246 (23%), Positives = 105/246 (43%), Gaps = 28/246 (11%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 R++ +V +K++D + +M H ++ ++ + G E ++ E+ Sbjct 424 AREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELWVLMEF 483 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 ++ G L + + R + V + + AL+YL + ++H ++ +ILL G Sbjct 484 LQGGALTDIVSQVRLNEEQI--ATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGR-- 539 Query 750 GTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSL-STAMDKWGFGATL 804 +KLSD G + R+ V W+APE + + SL +T +D W G + Sbjct 540 -----VKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVI---SRSLYATEVDIWSLGIMV 591 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------CPQLATLTSQCLTYEPTQRP 857 +E+ DGE P S SP + +R P P P L + L +P +R Sbjct 592 IEMV-DGEPPYFSDSPVQA---MKRLRDSPPPKLKNSHKVSPVLRDFLERMLVRDPQERA 647 Query 858 SFRTIL 863 + + +L Sbjct 648 TAQELL 653 >sp|Q64303|PAK2_RAT Serine/threonine-protein kinase PAK 2 OS=Rattus norvegicus OX=10116 GN=Pak2 PE=1 SV=1 Length=524 Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 60/209 (29%), Positives = 100/209 (48%), Gaps = 16/209 (8%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP + RY K +G+G G V + T+ G+ VA+K + P+ + E Sbjct 244 DPKKKYTRYEK----IGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINE 294 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +++ L + +I+ + E L +VMEY+ GSL D + + AQ+ ++ Sbjct 295 ILVMKELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCREC 352 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066 + + +LHA IHRD+ + NVLL + VK+ DFG A+ PE + R + Sbjct 353 LQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 408 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095 W APE + + D+WS G+ E++ Sbjct 409 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 437 Score = 37.4 bits (85), Expect = 0.82, Method: Compositional matrix adjust. Identities = 49/215 (23%), Positives = 90/215 (42%), Gaps = 26/215 (12%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719 +M ++ + ++ + G E +V EY+ G L DV +A V ++ Sbjct 297 VMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIA---AVCRECL 353 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777 AL +L ++H ++ N+LL EG+ +KL+D G A E+ +R Sbjct 354 QALEFLHANQVIHRDIKSDNVLLG----MEGS---VKLTD--FGFCAQITPEQSKRSTMV 404 Query 778 ----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---- 829 W+APE + A +D W G +E+ +GE P + +P + Sbjct 405 GTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNGTP 461 Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + + PE P ++CL + +R S + +L+ Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496 >sp|Q9NQU5|PAK6_HUMAN Serine/threonine-protein kinase PAK 6 OS=Homo sapiens OX=9606 GN=PAK6 PE=1 SV=1 Length=681 Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 63/213 (30%), Positives = 105/213 (49%), Gaps = 24/213 (11%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP + Y+K +GEG G V L +G VAVK + Q R E Sbjct 402 DPRLLLDSYVK----IGEGSTGIVCLA----REKHSGRQVAVKMMDLRKQ-QRRELLFNE 452 Query 948 IDILRTLYHEHIIK-YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006 + I+R H ++++ YK GE+ L ++ME++ G+L D + + + Q+ + Sbjct 453 VVIMRDYQHFNVVEMYKSYLV--GEE-LWVLMEFLQGGALTDIVSQVRLNEEQIATVCEA 509 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG----LAKAVPEGHEYYRVREDGD 1062 + + +AYLHAQ IHRD+ + ++LL D VK+ DFG ++K VP+ R+ Sbjct 510 VLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPK-------RKSLV 562 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 +W APE + + D+WS G+ + E++ Sbjct 563 GTPYWMAPEVISRSLYATEVDIWSLGIMVIEMV 595 Score = 47.4 bits (111), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 56/246 (23%), Positives = 105/246 (43%), Gaps = 28/246 (11%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 R++ +V +K++D + +M H ++ ++ + G E ++ E+ Sbjct 424 AREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELWVLMEF 483 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 ++ G L + + R + V + + AL+YL + ++H ++ +ILL G Sbjct 484 LQGGALTDIVSQVRLNEEQI--ATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGR-- 539 Query 750 GTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSL-STAMDKWGFGATL 804 +KLSD G + R+ V W+APE + + SL +T +D W G + Sbjct 540 -----VKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVI---SRSLYATEVDIWSLGIMV 591 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------CPQLATLTSQCLTYEPTQRP 857 +E+ DGE P S SP + +R P P P L + L +P +R Sbjct 592 IEMV-DGEPPYFSDSPVQA---MKRLRDSPPPKLKNSHKVSPVLRDFLERMLVRDPQERA 647 Query 858 SFRTIL 863 + + +L Sbjct 648 TAQELL 653 >sp|Q6FV07|IPL1_CANGA Spindle assembly checkpoint kinase OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=IPL1 PE=3 SV=1 Length=358 Score = 82.8 bits (203), Expect = 2e-15, Method: Composition-based stats. Identities = 76/249 (31%), Positives = 127/249 (51%), Gaps = 27/249 (11%) Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDP----TVFHKRYLKKI---RDLGEGHFGKVS 912 R L++ R +P ++ + ++P+S + T +K LK R LG+G FGKV Sbjct 57 RLFLKNQER-KPLGVSPLSNLSPNSLGRNSLEKSTYNNKLSLKDFEVGRKLGKGKFGKV- 114 Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGCCEDQG 970 YC + +G + A+KA++ + Q K+E+DI + H +IIK D Sbjct 115 -YCV--RHKKSGFICALKAIEKNEILQFNLLKQLKREVDIQLGMDHPNIIKLYAHFHD-- 169 Query 971 EKSLQLVMEYVPLG----SLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 EK + L+ME+ G SL++ P + + LA ++ QI + + Y+H + IHRD+ Sbjct 170 EKRVYLLMEHSINGELYKSLKNNGPFNDV-LASHYIY--QIADALHYMHKKRIIHRDVKP 226 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 NVL+ D +VK+ DFG + PEG + R+ + + +PE + ++ DVW+ Sbjct 227 ENVLIGFDNVVKLADFGWSILNPEGSK----RKTLCGTIDYLSPEMITPREYDEQVDVWA 282 Query 1087 FGVTLYELL 1095 GV YEL+ Sbjct 283 LGVLAYELV 291 Score = 39.7 bits (91), Expect = 0.14, Method: Composition-based stats. Identities = 40/150 (27%), Positives = 61/150 (41%), Gaps = 20/150 (13%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---GALSREERV 773 Q+A AL Y+ K ++H +V N+L+ G +KL+D G + R+ Sbjct 206 QIADALHYMHKKRIIHRDVKPENVLI-------GFDNVVKLADFGWSILNPEGSKRKTLC 258 Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR- 832 I +L+PE + +D W G E+ G P + S KE Y+R + Sbjct 259 GTIDYLSPEMIT--PREYDEQVDVWALGVLAYELVV-GVPPFEENS---KELTYKRILKC 312 Query 833 ---LPEPSCPQLATLTSQCLTYEPTQRPSF 859 PE L S+ L + TQR S Sbjct 313 DLNFPESISKDAKDLISKLLVTDTTQRLSL 342 >sp|Q6P9R2|OXSR1_MOUSE Serine/threonine-protein kinase OSR1 OS=Mus musculus OX=10090 GN=Oxsr1 PE=1 SV=1 Length=527 Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 61/200 (31%), Positives = 97/200 (49%), Gaps = 15/200 (8%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 E VA+K + + +EI + +H +I+ Y + E L LVM+ + G Sbjct 41 ERVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGG 98 Query 985 SLRDYLP------RHSIGLAQ---LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035 S+ D + H G+ + +++ EG+ YLH IHRD+ A N+LL D Sbjct 99 SVLDIIKHIVAKGEHKSGVLDEPTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG 158 Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092 V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAI 218 Query 1093 ELLTHCDS-SQSPPTKFLEL 1111 EL T + PP K L L Sbjct 219 ELATGAAPYHKYPPMKVLML 238 Score = 37.7 bits (86), Expect = 0.73, Method: Compositional matrix adjust. Identities = 42/169 (25%), Positives = 66/169 (39%), Gaps = 23/169 (14%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALS 768 + +++ L YL +H +V NILL G + G S F L+ G Sbjct 125 TILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAF--LATGGDITRNKV 182 Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------L 815 R+ V W+APE + D W FG T +E+ G AP L Sbjct 183 RKTFVGTPCWMAPEVME-QVRGYDFKADIWSFGITAIELA-TGAAPYHKYPPMKVLMLTL 240 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 Q+ PS + ++ + + + S CL +P +RP+ +LR Sbjct 241 QNDPPSLETGVQDKE--MLKKYGKSFRKMISLCLQKDPEKRPTAAELLR 287 >sp|A0A8I5ZNK2|OXSR1_RAT Serine/threonine-protein kinase OSR1 OS=Rattus norvegicus OX=10116 GN=Oxsr1 PE=1 SV=1 Length=528 Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 61/200 (31%), Positives = 98/200 (49%), Gaps = 15/200 (8%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 E VA+K + + +EI + +H +I+ Y + E L LVM+ + G Sbjct 41 ERVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGG 98 Query 985 SLRDYLP------RHSIGL---AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035 S+ D + H G+ + + +++ EG+ YLH IHRD+ A N+LL D Sbjct 99 SVLDIIKHIVAKGEHKGGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG 158 Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092 V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAI 218 Query 1093 ELLTHCDS-SQSPPTKFLEL 1111 EL T + PP K L L Sbjct 219 ELATGAAPYHKYPPMKVLML 238 Score = 37.4 bits (85), Expect = 1.0, Method: Compositional matrix adjust. Identities = 42/169 (25%), Positives = 65/169 (38%), Gaps = 23/169 (14%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALS 768 + +++ L YL +H +V NILL G + G S F L+ G Sbjct 125 TILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAF--LATGGDITRNKV 182 Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------L 815 R+ V W+APE + D W FG T +E+ G AP L Sbjct 183 RKTFVGTPCWMAPEVME-QVRGYDFKADIWSFGITAIELA-TGAAPYHKYPPMKVLMLTL 240 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 Q+ PS ++ + + + S CL +P +RP+ +LR Sbjct 241 QNDPPSLDTGVQDKE--MLKKYGKSFRKMISLCLQKDPEKRPTAAELLR 287 >sp|Q6I5Y0|CDKC1_ORYSJ Cyclin-dependent kinase C-1 OS=Oryza sativa subsp. japonica OX=39947 GN=CDKC-1 PE=2 SV=1 Length=519 Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 65/223 (29%), Positives = 105/223 (47%), Gaps = 34/223 (15%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILR 952 +K+ +GEG +G+V Y T E+VA+K ++ D R G+ +EI IL+ Sbjct 25 FEKLEQIGEGTYGQV----YMARETETQEIVALKKIRMD---NEREGFPITAIREIKILK 77 Query 953 TLYHEHIIKYKGCC-------EDQGEK--------SLQLVMEYVP--LGSLRDYLPRHSI 995 L+H+++I+ K ++QG+ S+ +V EY+ L L D P Sbjct 78 KLHHQNVIQLKEIVTSPGPERDEQGKPIHGNKYKGSIYMVFEYMDHDLTGLAD-RPGMRF 136 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + Q+ + +Q+ G+ Y H +HRD+ N+L+DN+ +K+ DFGLA++ H Sbjct 137 TVPQIKCYMKQLLTGLHYCHINQVLHRDIKGSNLLIDNEGNLKLADFGLARSFSNDHNGN 196 Query 1056 RVREDGDSPVFWYAPE--CLKEYKFYYASDVWSFGVTLYELLT 1096 WY P L K+ A D+WS G ELL Sbjct 197 LTNR---VITLWYRPPELLLGSTKYGPAVDMWSVGCIFAELLN 236 >sp|Q8GUH1|PUB33_ARATH U-box domain-containing protein 33 OS=Arabidopsis thaliana OX=3702 GN=PUB33 PE=2 SV=2 Length=834 Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 64/202 (32%), Positives = 95/202 (47%), Gaps = 21/202 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG +G + + T VA+K L + Q ++QE+D+L + H +II Sbjct 487 IGEGGYGSIYVGLLRHTQ------VAIKMLNPNSS-QGPVEYQQEVDVLSKMRHPNIITL 539 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLH--- 1015 G C + LV EY+P GSL D L + + A +IC + +LH Sbjct 540 IGACPE----GWSLVYEYLPGGSLEDRLTCKDNSPPLSWQNRVRIATEICAALVFLHSNK 595 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLK 1074 A +H DL N+LLD++ + K+ DFG + P G + VR D V + PE Sbjct 596 AHSLVHGDLKPANILLDSNLVSKLSDFGTCSLLHPNGSK--SVRTDVTGTVAYLDPEASS 653 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + SDV+SFG+ L LLT Sbjct 654 SGELTPKSDVYSFGIILLRLLT 675 Score = 49.3 bits (116), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 49/181 (27%), Positives = 89/181 (49%), Gaps = 22/181 (12%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K+L+P+ + + + ++S++ H ++ + G C G +V EY+ G L+ Sbjct 504 QVAIKMLNPNSSQGPVEYQQEVDVLSKMRHPNIITLIGACPEGWS--LVYEYLPGGSLED 561 Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYL-ENK--NLVHGNVCGRNILLARLGLAEGTS 752 L + P++W ++ +A ++ +AL +L NK +LVHG++ NILL ++ Sbjct 562 RLTCKDNSPPLSWQNRVRIATEICAALVFLHSNKAHSLVHGDLKPANILL-------DSN 614 Query 753 PFIKLSDPGVGL-----GALS-REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 KLSD G G+ S R + + +L PE G L+ D + FG LL Sbjct 615 LVSKLSDFGTCSLLHPNGSKSVRTDVTGTVAYLDPEASSSG--ELTPKSDVYSFGIILLR 672 Query 807 I 807 + Sbjct 673 L 673 >sp|C0LGG9|Y5344_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g53440 OS=Arabidopsis thaliana OX=3702 GN=At1g53440 PE=2 SV=2 Length=1035 Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 78/285 (27%), Positives = 125/285 (44%), Gaps = 35/285 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG V G +AVK L + +R + EI ++ L H +++K Sbjct 673 IGEGGFGPVYKGVL-----ADGMTIAVKQLSSKSKQGNRE-FVTEIGMISALQHPNLVKL 726 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLR-------------DYLPRHSIGLAQLLLFAQQICE 1009 GCC + K L LV EY+ SL D+ R+ + + I + Sbjct 727 YGCCIEG--KELLLVYEYLENNSLARALFGTEKQRLHLDWSTRNKVCIG--------IAK 776 Query 1010 GMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G+AYLH + +HRD+ A NVLLD KI DFGLAK E + + R G + Sbjct 777 GLAYLHEESRLKIVHRDIKATNVLLDLSLNAKISDFGLAKLDEEENTHISTRIAG--TIG 834 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 + APE +DV+SFGV E+++ +++ P +F+ L+ A L Sbjct 835 YMAPEYAMRGYLTDKADVYSFGVVCLEIVSGKSNTNYRPKEEFIYLLDWAYVLQEQGSLL 894 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 EL++ K + ++ C + RP +++ +L+ Sbjct 895 ELVDPDLGTSFSKKEAMRMLNIALLCTNPSPTLRPPMSSVVSMLQ 939 Score = 58.2 bits (139), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 70/270 (26%), Positives = 111/270 (41%), Gaps = 48/270 (18%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 + + +K L F ++S + H +L ++G C+ G E ++V EY+E+ L Sbjct 690 MTIAVKQLSSKSKQGNREFVTEIGMISALQHPNLVKLYGCCIEGKELLLVYEYLENNSLA 749 Query 697 VWL---RRERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEG 750 L ++R H+ + + V +A L+YL ++ +VH ++ N+LL L L Sbjct 750 RALFGTEKQRLHLDWSTRNKVCIGIAKGLAYLHEESRLKIVHRDIKATNVLL-DLSLNAK 808 Query 751 TSPFIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGAT 803 S F GL L EE I ++APE G L+ D + FG Sbjct 809 ISDF--------GLAKLDEEENTHISTRIAGTIGYMAPEYAMRGY--LTDKADVYSFGVV 858 Query 804 LLEICFDGEAPLQSRSPSEK-------EHFYQRQHRLPEPSCPQLATLTSQ--------- 847 LEI G++ R P E+ + Q Q L E P L T S+ Sbjct 859 CLEIV-SGKSNTNYR-PKEEFIYLLDWAYVLQEQGSLLELVDPDLGTSFSKKEAMRMLNI 916 Query 848 ---CLTYEPTQRP---SFRTILRDLTRLQP 871 C PT RP S ++L+ ++QP Sbjct 917 ALLCTNPSPTLRPPMSSVVSMLQGKIKVQP 946 >sp|Q8CIN4|PAK2_MOUSE Serine/threonine-protein kinase PAK 2 OS=Mus musculus OX=10090 GN=Pak2 PE=1 SV=1 Length=524 Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 60/209 (29%), Positives = 100/209 (48%), Gaps = 16/209 (8%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP + RY K +G+G G V + T+ G+ VA+K + P+ + E Sbjct 244 DPKKKYTRYEK----IGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINE 294 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +++ L + +I+ + E L +VMEY+ GSL D + + AQ+ ++ Sbjct 295 ILVMKELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCREC 352 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066 + + +LHA IHRD+ + NVLL + VK+ DFG A+ PE + R + Sbjct 353 LQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 408 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095 W APE + + D+WS G+ E++ Sbjct 409 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 437 Score = 37.4 bits (85), Expect = 0.84, Method: Compositional matrix adjust. Identities = 49/215 (23%), Positives = 90/215 (42%), Gaps = 26/215 (12%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719 +M ++ + ++ + G E +V EY+ G L DV +A V ++ Sbjct 297 VMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIA---AVCRECL 353 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777 AL +L ++H ++ N+LL EG+ +KL+D G A E+ +R Sbjct 354 QALEFLHANQVIHRDIKSDNVLLG----MEGS---VKLTD--FGFCAQITPEQSKRSTMV 404 Query 778 ----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---- 829 W+APE + A +D W G +E+ +GE P + +P + Sbjct 405 GTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNGTP 461 Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + + PE P ++CL + +R S + +L+ Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496 >sp|Q9FX99|Y1497_ARATH Probable receptor-like protein kinase At1g49730 OS=Arabidopsis thaliana OX=3702 GN=At1g49730 PE=2 SV=1 Length=663 Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 64/203 (32%), Positives = 102/203 (50%), Gaps = 19/203 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FG V + NDG + AVK + Q + +EI +L L+H +++ Sbjct 333 IGQGGFGTVYKAEF---NDGL--IAAVKKMNK-VSEQAEQDFCREIGLLAKLHHRNLVAL 386 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL-----AQLLLFAQQICEGMAYLHAQ 1017 KG C ++ E+ L V +Y+ GSL+D+L H+IG + A + + YLH Sbjct 387 KGFCINKKERFL--VYDYMKNGSLKDHL--HAIGKPPPSWGTRMKIAIDVANALEYLHFY 442 Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR-VREDGDSPVFWYAPECL 1073 HRD+ + N+LLD + + K+ DFGLA + +G + V D + PE + Sbjct 443 CDPPLCHRDIKSSNILLDENFVAKLSDFGLAHSSRDGSVCFEPVNTDIRGTPGYVDPEYV 502 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 + SDV+S+GV L EL+T Sbjct 503 VTQELTEKSDVYSYGVVLLELIT 525 >sp|Q29502|PAK2_RABIT Serine/threonine-protein kinase PAK 2 OS=Oryctolagus cuniculus OX=9986 GN=PAK2 PE=1 SV=1 Length=524 Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 60/209 (29%), Positives = 100/209 (48%), Gaps = 16/209 (8%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP + RY K +G+G G V + T+ G+ VA+K + P+ + E Sbjct 244 DPKKKYTRYEK----IGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINE 294 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +++ L + +I+ + E L +VMEY+ GSL D + + AQ+ ++ Sbjct 295 ILVMKELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCREC 352 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066 + + +LHA IHRD+ + NVLL + VK+ DFG A+ PE + R + Sbjct 353 LQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 408 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095 W APE + + D+WS G+ E++ Sbjct 409 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 437 Score = 37.4 bits (85), Expect = 0.88, Method: Compositional matrix adjust. Identities = 49/215 (23%), Positives = 90/215 (42%), Gaps = 26/215 (12%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719 +M ++ + ++ + G E +V EY+ G L DV +A V ++ Sbjct 297 VMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIA---AVCRECL 353 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777 AL +L ++H ++ N+LL EG+ +KL+D G A E+ +R Sbjct 354 QALEFLHANQVIHRDIKSDNVLLG----MEGS---VKLTD--FGFCAQITPEQSKRSTMV 404 Query 778 ----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---- 829 W+APE + A +D W G +E+ +GE P + +P + Sbjct 405 GTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNGTP 461 Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + + PE P ++CL + +R S + +L+ Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496 >sp|Q4P5N0|STE20_USTMA Serine/threonine-protein kinase SMU1 OS=Ustilago maydis (strain 521 / FGSC 9021) OX=237631 GN=SMU1 PE=3 SV=1 Length=746 Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 60/209 (29%), Positives = 104/209 (50%), Gaps = 14/209 (7%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 +DPT + R L+KI G+G G V + GT VA+K + + P+ + Sbjct 466 ADPTKLY-RSLQKI---GQGASGGV----FTAYQVGTNVSVAIKQMNLEQQPK-KDLIIN 516 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ 1006 EI +++ H +I+ + +G+ L +VMEY+ GSL D + + + Q+ +++ Sbjct 517 EILVMKESRHRNIVNFIDSFLFKGD--LWVVMEYMEGGSLTDVVTCNIMTEGQIAAVSRE 574 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 + EG+ +LH IHRD+ + NVLL +K+ DFG + E + R G + Sbjct 575 VLEGLRHLHQHGVIHRDIKSDNVLLSLQGDIKLTDFGFCAQIGES-QAKRTTMVGTP--Y 631 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095 W APE + ++ D+WS G+ E++ Sbjct 632 WMAPEVVTRKEYGPKVDIWSLGIMCIEMV 660 Score = 34.3 bits (77), Expect = 9.1, Method: Compositional matrix adjust. Identities = 39/168 (23%), Positives = 71/168 (42%), Gaps = 24/168 (14%) Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLR---RERGHVPMAWKMVVAQ 716 +M + H ++ F+ +G + +V EY+E G L + G + V++ Sbjct 520 VMKESRHRNIVNFIDSFLFKG-DLWVVMEYMEGGSLTDVVTCNIMTEGQI-----AAVSR 573 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREER 772 ++ L +L ++H ++ N+LL+ G IKL+D G +G R Sbjct 574 EVLEGLRHLHQHGVIHRDIKSDNVLLSLQG-------DIKLTDFGFCAQIGESQAKRTTM 626 Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 V W+APE + +D W G +E+ +GE P + +P Sbjct 627 VGTPYWMAPEVV--TRKEYGPKVDIWSLGIMCIEMV-EGEPPYLNENP 671 >sp|Q7RAH3|CDPK1_PLAYO Calcium-dependent protein kinase 1 OS=Plasmodium yoelii yoelii OX=73239 GN=CDPK1 PE=3 SV=3 Length=535 Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 67/210 (32%), Positives = 99/210 (47%), Gaps = 21/210 (10%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---------QEID 949 K+R LG G +G+V L C + + +K + D G + EI Sbjct 59 KVRKLGSGAYGEV-LLCKEKNGHSEKAIKVIKKSQFDKGRYNDDNKNIEKFHEEIYNEIS 117 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQIC 1008 +L++L H +IIK ED+ K LV E+ G L + RH +QI Sbjct 118 LLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQIL 175 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 G+ YLH + +HRD+ N+LL+N +KI DFGL+ + Y++R D Sbjct 176 SGICYLHKHNIVHRDIKPENILLENKNSLLNIKIVDFGLSSFFSKD---YKLR-DRLGTA 231 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 ++ APE LK+ K+ DVWS GV +Y LL Sbjct 232 YYIAPEVLKK-KYNEKCDVWSCGVIMYILL 260 Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust. Identities = 51/227 (22%), Positives = 88/227 (39%), Gaps = 29/227 (13%) Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVWL 699 K ++ H +I Y SL+ + H ++ + V +VTE+ E G L + Sbjct 103 KNIEKFHEEI----YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIIN 158 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R + A + +Q+ S + YL N+VH ++ NILL E + + + Sbjct 159 RHKFDECDAA---NIMKQILSGICYLHKHNIVHRDIKPENILL------ENKNSLLNIKI 209 Query 760 PGVGLGALSRE-----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATL-LEIC----F 809 GL + + +R+ ++APE L N D W G + + +C F Sbjct 210 VDFGLSSFFSKDYKLRDRLGTAYYIAPEVLKKKYNE---KCDVWSCGVIMYILLCGYPPF 266 Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 G+ EK +Y + S + L LTY+ +R Sbjct 267 GGQNDQDIIKKVEKGKYYFDFNDWKNIS-DEAKELIKLMLTYDYNKR 312 >sp|C0LGU1|Y5374_ARATH Probable LRR receptor-like serine/threonine-protein kinase At5g37450 OS=Arabidopsis thaliana OX=3702 GN=At5g37450 PE=1 SV=1 Length=959 Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 68/209 (33%), Positives = 107/209 (51%), Gaps = 23/209 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEH 958 + +G G +GKV Y G G +VAVK +A+ G Q + + EI++L L+H + Sbjct 634 LSQIGRGGYGKV----YKGHLPG-GLVVAVK--RAEQGSLQGQKEFFTEIELLSRLHHRN 686 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH 1015 ++ G C+ +GE+ LV EY+P GSL+D L R + LA L A G+ YLH Sbjct 687 LVSLLGYCDQKGEQ--MLVYEYMPNGSLQDALSARFRQPLSLALRLRIALGSARGILYLH 744 Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----W 1067 + IHRD+ N+LLD+ K+ DFG++K + + V+ D + + + Sbjct 745 TEADPPIIHRDIKPSNILLDSKMNPKVADFGISKLI--ALDGGGVQRDHVTTIVKGTPGY 802 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096 PE ++ SDV+S G+ E+LT Sbjct 803 VDPEYYLSHRLTEKSDVYSLGIVFLEILT 831 Score = 38.1 bits (87), Expect = 0.55, Method: Compositional matrix adjust. Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 4/92 (4%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMV 713 F+ L+S++ H +L + G C + E ++V EY+ +G L D R R + +A ++ Sbjct 672 FFTEIELLSRLHHRNLVSLLGYCDQKGEQMLVYEYMPNGSLQDALSARFRQPLSLALRLR 731 Query 714 VAQQLASALSYLENKN---LVHGNVCGRNILL 742 +A A + YL + ++H ++ NILL Sbjct 732 IALGSARGILYLHTEADPPIIHRDIKPSNILL 763 >sp|Q08E52|PAK1_BOVIN Serine/threonine-protein kinase PAK 1 OS=Bos taurus OX=9913 GN=PAK1 PE=1 SV=1 Length=544 Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 63/237 (27%), Positives = 105/237 (44%), Gaps = 28/237 (12%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDL----------------GEGHFGKVSLYCYDPT 919 D LT N + P + + L+K+R + G+G G V Y Sbjct 232 DALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV----YTAM 287 Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979 + TG+ VA+K + P+ + EI ++R + +I+ Y E L +VME Sbjct 288 DVATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVME 344 Query 980 YVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 Y+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+LL D VK+ Sbjct 345 YLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKL 404 Query 1040 GDFGL-AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 DFG A+ PE + R +W APE + + D+WS G+ E++ Sbjct 405 TDFGFCAQITPEQSK----RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI 457 Score = 34.3 bits (77), Expect = 9.5, Method: Compositional matrix adjust. Identities = 40/150 (27%), Positives = 64/150 (43%), Gaps = 26/150 (17%) Query 680 GPENIMVTEYVEHGPL-DVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736 G E +V EY+ G L DV + G + V ++ AL +L + ++H ++ Sbjct 336 GDELWVVMEYLAGGSLTDVVTETCMDEGQI-----AAVCRECLQALEFLHSNQVIHRDIK 390 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANS 790 NILL G +KL+D G A E+ +R W+APE + A Sbjct 391 SDNILLGMDG-------SVKLTD--FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-- 439 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +D W G +E+ +GE P + +P Sbjct 440 YGPKVDIWSLGIMAIEM-IEGEPPYLNENP 468 >sp|Q9SXB8|Y1133_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g11330 OS=Arabidopsis thaliana OX=3702 GN=At1g11330 PE=1 SV=3 Length=842 Score = 84.7 bits (208), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 88/289 (30%), Positives = 124/289 (43%), Gaps = 41/289 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG P G G+ +AVK L G Q E+ ++ L H ++ Sbjct 530 LGQGGFG--------PVYKGKLPEGQEIAVKRLSRKSG-QGLEELMNEVVVISKLQHRNL 580 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015 +K GCC + E+ LV EY+P SL YL + + + IC G+ YLH Sbjct 581 VKLLGCCIEGEER--MLVYEYMPKKSLDAYLFDPMKQKILDWKTRFNIMEGICRGLLYLH 638 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 IHRDL A N+LLD + KI DFGLA+ + R + + +PE Sbjct 639 RDSRLKIIHRDLKASNILLDENLNPKISDFGLARIFRANEDEANTRRVVGTYGY-MSPEY 697 Query 1073 LKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 E F SDV+S GV E+++ +SS L L+ A +L G Sbjct 698 AMEGFFSEKSDVFSLGVIFLEIISGRRNSSSHKEENNLNLLAYAW---------KLWNDG 748 Query 1132 E--RLPRP---DKC----PCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 E L P DKC + H+ C + A+ RP N+I +L T Sbjct 749 EAASLADPAVFDKCFEKEIEKCVHIGLLCVQEVANDRPNVSNVIWMLTT 797 Score = 41.6 bits (96), Expect = 0.058, Method: Compositional matrix adjust. Identities = 57/226 (25%), Positives = 89/226 (39%), Gaps = 45/226 (20%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 + LGQG VY+G+L PE GQE+ V K L Sbjct 528 NKLGQGGFGPVYKGKL-------PE----------------GQEIAV--KRLSRKSGQGL 562 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK- 711 ++S++ H +L + G C+ G E ++V EY+ LD +L + WK Sbjct 563 EELMNEVVVISKLQHRNLVKLLGCCIEGEERMLVYEYMPKKSLDAYLFDPMKQKILDWKT 622 Query 712 -MVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LG 765 + + + L YL + ++H ++ NIL L E +P K+SD G+ Sbjct 623 RFNIMEGICRGLLYLHRDSRLKIIHRDLKASNIL-----LDENLNP--KISDFGLARIFR 675 Query 766 ALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 A E R+ +++PE G S D + G LEI Sbjct 676 ANEDEANTRRVVGTYGYMSPEYAMEGF--FSEKSDVFSLGVIFLEI 719 >sp|Q9LK35|THE1_ARATH Receptor-like protein kinase THESEUS 1 OS=Arabidopsis thaliana OX=3702 GN=THE1 PE=1 SV=1 Length=855 Score = 84.7 bits (208), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 69/203 (34%), Positives = 99/203 (49%), Gaps = 23/203 (11%) Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHEH 958 LG G FG+V Y T DGT VAVK P+ G ++ EI++L L H H Sbjct 516 LGVGGFGRV----YKGTLEDGTK--VAVKR----GNPRSEQGMAEFRTEIEMLSKLRHRH 565 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI---GLAQLLLFAQQICEGMAYLH 1015 ++ G C+++ E + LV EY+ G LR +L + Q L G+ YLH Sbjct 566 LVSLIGYCDERSE--MILVYEYMANGPLRSHLYGADLPPLSWKQRLEICIGAARGLHYLH 623 Query 1016 ---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 +Q IHRD+ N+LLD + + K+ DFGL+K P + + V + PE Sbjct 624 TGASQSIIHRDVKTTNILLDENLVAKVADFGLSKTGPSLDQTH-VSTAVKGSFGYLDPEY 682 Query 1073 LKEYKFYYASDVWSFGVTLYELL 1095 + + SDV+SFGV L E+L Sbjct 683 FRRQQLTEKSDVYSFGVVLMEVL 705 Score = 44.3 bits (103), Expect = 0.008, Method: Compositional matrix adjust. Identities = 61/258 (24%), Positives = 102/258 (40%), Gaps = 40/258 (16%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K +P F ++S++ H HL + G C E I+V EY+ +GPL Sbjct 534 KVAVKRGNPRSEQGMAEFRTEIEMLSKLRHRHLVSLIGYCDERSEMILVYEYMANGPL-- 591 Query 698 WLRRERGHV------PMAWK--MVVAQQLASALSYL---ENKNLVHGNVCGRNILLARLG 746 R H+ P++WK + + A L YL +++++H +V NILL Sbjct 592 -----RSHLYGADLPPLSWKQRLEICIGAARGLHYLHTGASQSIIHRDVKTTNILLDE-N 645 Query 747 LAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 L + F LS G L V+ +L PE L+ D + FG L+ Sbjct 646 LVAKVADF-GLSKTGPSLDQTHVSTAVKGSFGYLDPEYFR--RQQLTEKSDVYSFGVVLM 702 Query 806 EI-----CFDGEAPLQSRSPSEKEHFYQRQHRLPE------------PSCPQLATLTSQC 848 E+ + P + + +E +Q++ L + S + +C Sbjct 703 EVLCCRPALNPVLPREQVNIAEWAMAWQKKGLLDQIMDSNLTGKVNPASLKKFGETAEKC 762 Query 849 LTYEPTQRPSFRTILRDL 866 L RPS +L +L Sbjct 763 LAEYGVDRPSMGDVLWNL 780 >sp|G5EGT9|RYK_CAEEL Inactive tyrosine-protein kinase RYK OS=Caenorhabditis elegans OX=6239 GN=lin-18 PE=1 SV=1 Length=583 Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 49/171 (29%), Positives = 92/171 (54%), Gaps = 18/171 (11%) Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD--NDRL-VKIGDFGLAKAVPEGHEYY 1055 QL+ A Q+ +A++H +H D+AARN L+ N RL V++ D L++ + +Y+ Sbjct 414 QLVSLATQVSSAVAHIHKYRIVHNDIAARNCLIAEVNGRLQVQLCDSALSRDLFPA-DYH 472 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 + ++ + P+ W +PE + + A+DVWS GV L+EL++ L G Sbjct 473 CLGDNENRPLKWMSPEAIANELYSSAADVWSLGVLLWELMS--------------LGGSP 518 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 ++ + ++ +G+RL +P+ CP ++Y +M CW + RP+ E ++ Sbjct 519 HAEIDPEEVYTMILKGKRLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQVV 569 Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 47/164 (29%), Positives = 72/164 (44%), Gaps = 15/164 (9%) Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLA----RLGLAEGTSPFIKLSDPGVGLGALSR 769 +A Q++SA++++ +VH ++ RN L+A RL + S + P Sbjct 418 LATQVSSAVAHIHKYRIVHNDIAARNCLIAEVNGRLQVQLCDSALSRDLFPADYHCLGDN 477 Query 770 EERVERIPWLAPECLPGGANSL-STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 E R + W++PE + AN L S+A D W G L E+ G +P P E Sbjct 478 ENR--PLKWMSPEAI---ANELYSSAADVWSLGVLLWELMSLGGSPHAEIDPEEVYTMIL 532 Query 829 RQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTI---LRDLT 867 + RL +P +CP QL + C RPS + LRD Sbjct 533 KGKRLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQVVHGLRDFN 576 >sp|P0CY24|STE20_CANAL Serine/threonine-protein kinase CST20 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=CST20 PE=3 SV=1 Length=1228 Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 56/195 (29%), Positives = 103/195 (53%), Gaps = 13/195 (7%) Query 903 LGEGHFGKVSLY--CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G+G G V L D +N +VA+K + + P+ + EI +++ H +I+ Sbjct 957 IGQGASGGVFLAHDVRDKSN-----IVAIKQMNLEQQPK-KELIINEILVMKGSSHPNIV 1010 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + +G+ L ++MEY+ GSL D + + Q+ + ++ +G+ +LH++ I Sbjct 1011 NFIDSYLLKGD--LWVIMEYMEGGSLTDIVTHSVMTEGQIGVVCRETLKGLKFLHSKGVI 1068 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ + N+LL+ D +KI DFG + E + R+ G +P +W APE + ++ Sbjct 1069 HRDIKSDNILLNMDGNIKITDFGFCAQINEINS-KRITMVG-TP-YWMAPEIVSRKEYGP 1125 Query 1081 ASDVWSFGVTLYELL 1095 DVWS G+ + E+L Sbjct 1126 KVDVWSLGIMIIEML 1140 Score = 38.9 bits (89), Expect = 0.36, Method: Compositional matrix adjust. Identities = 43/169 (25%), Positives = 74/169 (44%), Gaps = 26/169 (15%) Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM--VVAQQ 717 +M SH ++ F+ ++G + ++ EY+E G L + H M VV ++ Sbjct 1000 VMKGSSHPNIVNFIDSYLLKG-DLWVIMEYMEGGSLTDIVT----HSVMTEGQIGVVCRE 1054 Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP 777 L +L +K ++H ++ NILL G IK++D G A E +RI Sbjct 1055 TLKGLKFLHSKGVIHRDIKSDNILLNMDG-------NIKITD--FGFCAQINEINSKRIT 1105 Query 778 ------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 W+APE + +D W G ++E+ +GE P + +P Sbjct 1106 MVGTPYWMAPEIV--SRKEYGPKVDVWSLGIMIIEM-LEGEPPYLNETP 1151 >sp|Q66GN2|LRK64_ARATH Lectin-domain containing receptor kinase VI.4 OS=Arabidopsis thaliana OX=3702 GN=LECRK64 PE=2 SV=1 Length=691 Score = 84.7 bits (208), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 66/209 (32%), Positives = 104/209 (50%), Gaps = 18/209 (9%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 K+ R +G G FG V Y + + +AVK + + R + EI+ L L H Sbjct 363 FKENRVVGTGGFGIV----YRGNIRSSSDQIAVKKITPNSMQGVRE-FVAEIESLGRLRH 417 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHS---IGLAQLLLFAQQICEG 1010 ++++ +G C+ + + L L+ +Y+P GSL L PR S + A+ I G Sbjct 418 KNLVNLQGWCKHRND--LLLIYDYIPNGSLDSLLYSKPRRSGAVLSWNARFQIAKGIASG 475 Query 1011 MAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH Q IHRD+ NVL+D+D ++GDFGLA+ G + G + + Sbjct 476 LLYLHEEWEQIVIHRDVKPSNVLIDSDMNPRLGDFGLARLYERGSQSCTTVVVG--TIGY 533 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096 APE + ASDV++FGV L E+++ Sbjct 534 MAPELARNGNSSSASDVFAFGVLLLEIVS 562 Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 58/267 (22%), Positives = 110/267 (41%), Gaps = 40/267 (15%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G R ++ +K + P+ F + ++ H +L + G C + +++ +Y Sbjct 380 GNIRSSSDQIAVKKITPNSMQGVREFVAEIESLGRLRHKNLVNLQGWCKHRNDLLLIYDY 439 Query 690 VEHGPLD--VWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILL 742 + +G LD ++ + R ++W + +A+ +AS L YL + ++H +V N+L+ Sbjct 440 IPNGSLDSLLYSKPRRSGAVLSWNARFQIAKGIASGLLYLHEEWEQIVIHRDVKPSNVLI 499 Query 743 -ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 + + G +L + G V I ++APE G + S+A D + FG Sbjct 500 DSDMNPRLGDFGLARLYERG---SQSCTTVVVGTIGYMAPELARNGNS--SSASDVFAFG 554 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY--------QRQHRLPEPSCPQLATLTSQ------ 847 LLEI + R P++ F+ Q + P+L + + Sbjct 555 VLLLEI-------VSGRKPTDSGTFFIADWVMELQASGEILSAIDPRLGSGYDEGEARLA 607 Query 848 ------CLTYEPTQRPSFRTILRDLTR 868 C ++P RP R +LR L R Sbjct 608 LAVGLLCCHHKPESRPLMRMVLRYLNR 634 >sp|O88643|PAK1_MOUSE Serine/threonine-protein kinase PAK 1 OS=Mus musculus OX=10090 GN=Pak1 PE=1 SV=1 Length=545 Score = 84.0 bits (206), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 63/237 (27%), Positives = 105/237 (44%), Gaps = 28/237 (12%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDL----------------GEGHFGKVSLYCYDPT 919 D LT N + P + + L+K+R + G+G G V Y Sbjct 233 DALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTPFEKIGQGASGTV----YTAM 288 Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979 + TG+ VA+K + P+ + EI ++R + +I+ Y E L +VME Sbjct 289 DVATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVME 345 Query 980 YVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 Y+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+LL D VK+ Sbjct 346 YLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKL 405 Query 1040 GDFGL-AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 DFG A+ PE + R +W APE + + D+WS G+ E++ Sbjct 406 TDFGFCAQITPEQSK----RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI 458 Score = 34.3 bits (77), Expect = 7.7, Method: Compositional matrix adjust. Identities = 40/150 (27%), Positives = 64/150 (43%), Gaps = 26/150 (17%) Query 680 GPENIMVTEYVEHGPL-DVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736 G E +V EY+ G L DV + G + V ++ AL +L + ++H ++ Sbjct 337 GDELWVVMEYLAGGSLTDVVTETCMDEGQI-----AAVCRECLQALEFLHSNQVIHRDIK 391 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANS 790 NILL G +KL+D G A E+ +R W+APE + A Sbjct 392 SDNILLGMDG-------SVKLTD--FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-- 440 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +D W G +E+ +GE P + +P Sbjct 441 YGPKVDIWSLGIMAIEM-IEGEPPYLNENP 469 >sp|Q39030|KPK2_ARATH Serine/threonine-protein kinase AtPK2/AtPK19 OS=Arabidopsis thaliana OX=3702 GN=ATPK2 PE=1 SV=2 Length=471 Score = 83.6 bits (205), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 80/279 (29%), Positives = 120/279 (43%), Gaps = 23/279 (8%) Query 827 YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD--- 883 Y R H L PS +L LT T+ L + + D + N D Sbjct 68 YSRSHSLVGPSLVVSHSLKMNKLTLRETED---SVDLVECVEGESIKENDEFSGNDDTDS 124 Query 884 --SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQ 939 SP V + ++ +G+G FGKV Y T E+ A+K ++ D Sbjct 125 EKSPEEVSGVVGIEDFEVLKVVGQGAFGKV----YQVRKKDTSEIYAMKVMRKDKIVEKN 180 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ 999 H K E DIL + H I++ K Q + L LV++++ G L L + Sbjct 181 HAEYMKAERDILTKIDHPFIVQLKYSF--QTKYRLYLVLDFINGGHLFFQLYHQGLFRED 238 Query 1000 LL-LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 L ++ +I +++LH + +HRDL N+L+D D V + DFGLAK E R Sbjct 239 LARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDVDGHVMLTDFGLAKEFEEN-----TR 293 Query 1059 EDGDSPVFWY-APECLKEYKFYYASDVWSFGVTLYELLT 1096 + Y APE ++ A+D WS G+ LYE+LT Sbjct 294 SNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLT 332 Score = 34.3 bits (77), Expect = 9.0, Method: Compositional matrix adjust. Identities = 36/150 (24%), Positives = 62/150 (41%), Gaps = 19/150 (13%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 V ++ SA+S+L K ++H ++ NIL+ G + L+D G+ A EE Sbjct 242 VYTAEIVSAVSHLHEKGIMHRDLKPENILMDVDG-------HVMLTDFGL---AKEFEEN 291 Query 773 VER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 ++APE + G + A D W G L E+ G+ P ++ Sbjct 292 TRSNSMCGTTEYMAPEIVRGKGH--DKAADWWSVGILLYEM-LTGKPPFLGSKGKIQQKI 348 Query 827 YQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 + + +LP+ + L L EP +R Sbjct 349 VKDKIKLPQFLSNEAHALLKGLLQKEPERR 378 >sp|Q13153|PAK1_HUMAN Serine/threonine-protein kinase PAK 1 OS=Homo sapiens OX=9606 GN=PAK1 PE=1 SV=2 Length=545 Score = 84.0 bits (206), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 63/237 (27%), Positives = 105/237 (44%), Gaps = 28/237 (12%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDL----------------GEGHFGKVSLYCYDPT 919 D LT N + P + + L+K+R + G+G G V Y Sbjct 233 DALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV----YTAM 288 Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979 + TG+ VA+K + P+ + EI ++R + +I+ Y E L +VME Sbjct 289 DVATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVME 345 Query 980 YVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 Y+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+LL D VK+ Sbjct 346 YLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKL 405 Query 1040 GDFGL-AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 DFG A+ PE + R +W APE + + D+WS G+ E++ Sbjct 406 TDFGFCAQITPEQSK----RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI 458 Score = 33.9 bits (76), Expect = 9.8, Method: Compositional matrix adjust. Identities = 40/150 (27%), Positives = 64/150 (43%), Gaps = 26/150 (17%) Query 680 GPENIMVTEYVEHGPL-DVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736 G E +V EY+ G L DV + G + V ++ AL +L + ++H ++ Sbjct 337 GDELWVVMEYLAGGSLTDVVTETCMDEGQI-----AAVCRECLQALEFLHSNQVIHRDIK 391 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANS 790 NILL G +KL+D G A E+ +R W+APE + A Sbjct 392 SDNILLGMDG-------SVKLTD--FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-- 440 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +D W G +E+ +GE P + +P Sbjct 441 YGPKVDIWSLGIMAIEM-IEGEPPYLNENP 469 >sp|C4YRB7|STE20_CANAW Serine/threonine-protein kinase CST20 OS=Candida albicans (strain WO-1) OX=294748 GN=CST20 PE=3 SV=2 Length=1224 Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 56/195 (29%), Positives = 103/195 (53%), Gaps = 13/195 (7%) Query 903 LGEGHFGKVSLY--CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G+G G V L D +N +VA+K + + P+ + EI +++ H +I+ Sbjct 953 IGQGASGGVFLAHDVRDKSN-----IVAIKQMNLEQQPK-KELIINEILVMKGSSHPNIV 1006 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + +G+ L ++MEY+ GSL D + + Q+ + ++ +G+ +LH++ I Sbjct 1007 NFIDSYLLKGD--LWVIMEYMEGGSLTDIVTHSVMTEGQIGVVCRETLKGLKFLHSKGVI 1064 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ + N+LL+ D +KI DFG + E + R+ G +P +W APE + ++ Sbjct 1065 HRDIKSDNILLNMDGNIKITDFGFCAQINEINS-KRITMVG-TP-YWMAPEIVSRKEYGP 1121 Query 1081 ASDVWSFGVTLYELL 1095 DVWS G+ + E+L Sbjct 1122 KVDVWSLGIMIIEML 1136 Score = 38.9 bits (89), Expect = 0.36, Method: Compositional matrix adjust. Identities = 43/169 (25%), Positives = 74/169 (44%), Gaps = 26/169 (15%) Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM--VVAQQ 717 +M SH ++ F+ ++G + ++ EY+E G L + H M VV ++ Sbjct 996 VMKGSSHPNIVNFIDSYLLKG-DLWVIMEYMEGGSLTDIVT----HSVMTEGQIGVVCRE 1050 Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP 777 L +L +K ++H ++ NILL G IK++D G A E +RI Sbjct 1051 TLKGLKFLHSKGVIHRDIKSDNILLNMDG-------NIKITD--FGFCAQINEINSKRIT 1101 Query 778 ------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 W+APE + +D W G ++E+ +GE P + +P Sbjct 1102 MVGTPYWMAPEIV--SRKEYGPKVDVWSLGIMIIEM-LEGEPPYLNETP 1147 >sp|Q9LVP0|Y5639_ARATH Probable leucine-rich repeat receptor-like protein kinase At5g63930 OS=Arabidopsis thaliana OX=3702 GN=At5g63930 PE=1 SV=1 Length=1102 Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 61/182 (34%), Positives = 90/182 (49%), Gaps = 13/182 (7%) Query 924 GEMVAVKALKAD--CGPQHR--SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979 G +AVK L ++ G + + ++ EI L + H +I+K G C QG L+ E Sbjct 826 GYTLAVKKLASNHEGGNNNNVDNSFRAEILTLGNIRHRNIVKLHGFCNHQGSN--LLLYE 883 Query 980 YVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDND 1034 Y+P GSL + L P ++ ++ A +G+AYLH HRD+ + N+LLD+ Sbjct 884 YMPKGSLGEILHDPSCNLDWSKRFKIALGAAQGLAYLHHDCKPRIFHRDIKSNNILLDDK 943 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 +GDFGLAK + H G + APE K SD++S+GV L EL Sbjct 944 FEAHVGDFGLAKVIDMPHSKSMSAIAGSYG--YIAPEYAYTMKVTEKSDIYSYGVVLLEL 1001 Query 1095 LT 1096 LT Sbjct 1002 LT 1003 >sp|Q9URY1|PPK16_SCHPO Serine/threonine-protein kinase ppk16 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ppk16 PE=1 SV=1 Length=672 Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 64/196 (33%), Positives = 91/196 (46%), Gaps = 16/196 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK- 961 +GEG FGKV L + TN LK+ C Q +EI R L H +I + Sbjct 37 VGEGSFGKVYLAAHLLTNTKV-------VLKSSCRKQ-AIILAREIHHHRRLLHPNITRL 88 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020 Y+ C E + L MEY P G L D++ R + Q+C + YLH Q + Sbjct 89 YEVVC---TEDRIYLAMEYCPNGELYDWVAREKRLDEKTTCRIMWQLCCAIQYLHRQGCV 145 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 HRDL N+ LD VK+GDFG ++ + G V + APE ++ +K+ Sbjct 146 HRDLKLENIFLDKAYNVKLGDFGFSRDSDCSRRTFMNTRCGT--VAYCAPELVQGHKYIG 203 Query 1080 YASDVWSFGVTLYELL 1095 D+WS G+ +Y LL Sbjct 204 ECVDIWSLGIIMYALL 219 >sp|Q54Y90|Y0133_DICDI Probable serine/threonine-protein kinase DDB_G0278665 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0278665 PE=3 SV=1 Length=1090 Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 64/232 (28%), Positives = 109/232 (47%), Gaps = 28/232 (12%) Query 942 SGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLA 998 S +++E+++ + L +H +I+ + G C LV+EY+ GSL YL P ++ Sbjct 228 SEFEKELEMHKELLHHPNIVHFVGFCVSPK----CLVLEYIEGGSLDKYLHNPNYTFSPQ 283 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL-----DNDRLVKIGDFGLAKAVPEGHE 1053 L A I +GM +LH +H DL +N L+ + +K+ DFGLA + Sbjct 284 LRLKMANDIAKGMCFLHRNEILHLDLKPQNFLVVSISPEAPVSIKLADFGLATS--SSRS 341 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 +Y +G + +PE + KF A+DVWS+G L E+LT+ Q Sbjct 342 FYGPTVEGS--FLYMSPEVFTQKKFSRAADVWSYGACLIEILTNKRPYQE---------- 389 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 Q+ L L + E G P + ++ +++ C+ + + RP FEN+ Sbjct 390 --YDQLGYLELARVREEGLPPMIPPEIEGDLRKIIEACFHRDHTKRPNFENI 439 Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 51/204 (25%), Positives = 85/204 (42%), Gaps = 15/204 (7%) Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726 H ++ G CV +V EY+E G LD +L ++ +A +A + +L Sbjct 243 HPNIVHFVGFCVS--PKCLVLEYIEGGSLDKYLHNPNYTFSPQLRLKMANDIAKGMCFLH 300 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVE-RIPWLAPE 782 ++H ++ +N L+ + S IKL+D G+ + SR VE +++PE Sbjct 301 RNEILHLDLKPQNFLVVSISPEAPVS--IKLADFGLATSS-SRSFYGPTVEGSFLYMSPE 357 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ-- 840 S A D W +GA L+EI + + E R+ LP P+ Sbjct 358 VF--TQKKFSRAADVWSYGACLIEILTNKRPYQEYDQLGYLELARVREEGLPPMIPPEIE 415 Query 841 --LATLTSQCLTYEPTQRPSFRTI 862 L + C + T+RP+F I Sbjct 416 GDLRKIIEACFHRDHTKRPNFENI 439 >sp|P0CY23|STE20_CANAX Serine/threonine-protein kinase CST20 OS=Candida albicans OX=5476 GN=CST20 PE=3 SV=1 Length=1230 Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 56/195 (29%), Positives = 103/195 (53%), Gaps = 13/195 (7%) Query 903 LGEGHFGKVSLY--CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G+G G V L D +N +VA+K + + P+ + EI +++ H +I+ Sbjct 959 IGQGASGGVFLAHDVRDKSN-----IVAIKQMNLEQQPK-KELIINEILVMKGSSHPNIV 1012 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + +G+ L ++MEY+ GSL D + + Q+ + ++ +G+ +LH++ I Sbjct 1013 NFIDSYLLKGD--LWVIMEYMEGGSLTDIVTHSVMTEGQIGVVCRETLKGLKFLHSKGVI 1070 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ + N+LL+ D +KI DFG + E + R+ G +P +W APE + ++ Sbjct 1071 HRDIKSDNILLNMDGNIKITDFGFCAQINEINS-KRITMVG-TP-YWMAPEIVSRKEYGP 1127 Query 1081 ASDVWSFGVTLYELL 1095 DVWS G+ + E+L Sbjct 1128 KVDVWSLGIMIIEML 1142 Score = 38.9 bits (89), Expect = 0.36, Method: Compositional matrix adjust. Identities = 43/169 (25%), Positives = 74/169 (44%), Gaps = 26/169 (15%) Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM--VVAQQ 717 +M SH ++ F+ ++G + ++ EY+E G L + H M VV ++ Sbjct 1002 VMKGSSHPNIVNFIDSYLLKG-DLWVIMEYMEGGSLTDIVT----HSVMTEGQIGVVCRE 1056 Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP 777 L +L +K ++H ++ NILL G IK++D G A E +RI Sbjct 1057 TLKGLKFLHSKGVIHRDIKSDNILLNMDG-------NIKITD--FGFCAQINEINSKRIT 1107 Query 778 ------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 W+APE + +D W G ++E+ +GE P + +P Sbjct 1108 MVGTPYWMAPEIV--SRKEYGPKVDVWSLGIMIIEM-LEGEPPYLNETP 1153 >sp|P35465|PAK1_RAT Serine/threonine-protein kinase PAK 1 OS=Rattus norvegicus OX=10116 GN=Pak1 PE=1 SV=3 Length=544 Score = 84.0 bits (206), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 63/237 (27%), Positives = 105/237 (44%), Gaps = 28/237 (12%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDL----------------GEGHFGKVSLYCYDPT 919 D LT N + P + + L+K+R + G+G G V Y Sbjct 232 DALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV----YTAM 287 Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979 + TG+ VA+K + P+ + EI ++R + +I+ Y E L +VME Sbjct 288 DVATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVME 344 Query 980 YVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 Y+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+LL D VK+ Sbjct 345 YLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKL 404 Query 1040 GDFGL-AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 DFG A+ PE + R +W APE + + D+WS G+ E++ Sbjct 405 TDFGFCAQITPEQSK----RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI 457 Score = 33.9 bits (76), Expect = 9.9, Method: Compositional matrix adjust. Identities = 40/150 (27%), Positives = 64/150 (43%), Gaps = 26/150 (17%) Query 680 GPENIMVTEYVEHGPL-DVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736 G E +V EY+ G L DV + G + V ++ AL +L + ++H ++ Sbjct 336 GDELWVVMEYLAGGSLTDVVTETCMDEGQI-----AAVCRECLQALEFLHSNQVIHRDIK 390 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANS 790 NILL G +KL+D G A E+ +R W+APE + A Sbjct 391 SDNILLGMDG-------SVKLTD--FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-- 439 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +D W G +E+ +GE P + +P Sbjct 440 YGPKVDIWSLGIMAIEM-IEGEPPYLNENP 468 >sp|Q6C7U8|PHO85_YARLI Negative regulator of the PHO system OS=Yarrowia lipolytica (strain CLIB 122 / E 150) OX=284591 GN=PHO85 PE=3 SV=1 Length=294 Score = 81.3 bits (199), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 58/206 (28%), Positives = 98/206 (48%), Gaps = 17/206 (8%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +++ LGEG + V Y N TG++VA+K + D S +EI +++ L H Sbjct 7 FQQLEKLGEGTYATV----YKGRNRTTGQLVALKEINLDSEEGTPSTAIREISLMKELKH 62 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----SIGLAQLLLFAQQICEGMA 1012 E+I+ E L LV EY+ L+ ++ + ++ Q+ F Q+ G+ Sbjct 63 ENIVTLYDVI--HTENKLNLVFEYMD-KDLKKFMDTNGNKGALETKQVKWFMYQLLRGIL 119 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APE 1071 + H +HRDL +N+L++ +K+ DFGLA+A + + WY AP+ Sbjct 120 FCHDNRVLHRDLKPQNLLINAKGQLKLADFGLARAFGIPVNTF----SNEVVTLWYRAPD 175 Query 1072 CLKEYKFYYAS-DVWSFGVTLYELLT 1096 L + Y S D+WS G + E+ T Sbjct 176 VLLGSRTYSTSIDIWSAGCIMAEMFT 201 >sp|A0A509AHB6|CDPK1_PLABA Calcium-dependent protein kinase 1 OS=Plasmodium berghei (strain Anka) OX=5823 GN=CDPK1 PE=1 SV=1 Length=523 Score = 84.0 bits (206), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 67/210 (32%), Positives = 98/210 (47%), Gaps = 21/210 (10%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK---------QEID 949 K+R LG G +G+V L C + + +K + D G EI Sbjct 59 KVRKLGSGAYGEV-LLCKEKNGHSEKAIKVIKKSQFDKGRYSDDNKNIEKFHEEIYNEIS 117 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQIC 1008 +L++L H +IIK ED+ K LV E+ G L + RH +QI Sbjct 118 LLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQIL 175 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 G+ YLH + +HRD+ N+LL+N +KI DFGL+ + Y++R D Sbjct 176 SGICYLHKHNIVHRDIKPENILLENKNSLLNIKIVDFGLSSFFSKD---YKLR-DRLGTA 231 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 ++ APE LK+ K+ DVWS GV +Y LL Sbjct 232 YYIAPEVLKK-KYNEKCDVWSCGVIMYILL 260 Score = 38.5 bits (88), Expect = 0.45, Method: Compositional matrix adjust. Identities = 52/227 (23%), Positives = 90/227 (40%), Gaps = 29/227 (13%) Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVWL 699 K ++ H +I Y SL+ + H ++ + V +VTE+ E G L + Sbjct 103 KNIEKFHEEI----YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIIN 158 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R + A + +Q+ S + YL N+VH ++ NILL E + + + Sbjct 159 RHKFDECDAA---NIMKQILSGICYLHKHNIVHRDIKPENILL------ENKNSLLNIKI 209 Query 760 PGVGLGA-LSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATL-LEIC----F 809 GL + S++ +R+ ++APE L N D W G + + +C F Sbjct 210 VDFGLSSFFSKDYKLRDRLGTAYYIAPEVLKKKYNE---KCDVWSCGVIMYILLCGYPPF 266 Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 G+ EK +Y + S + L LTY+ +R Sbjct 267 GGQNDQDIIKKVEKGKYYFDFNDWKNIS-DEAKELIKLMLTYDYNKR 312 >sp|Q13177|PAK2_HUMAN Serine/threonine-protein kinase PAK 2 OS=Homo sapiens OX=9606 GN=PAK2 PE=1 SV=3 Length=524 Score = 84.0 bits (206), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 60/209 (29%), Positives = 100/209 (48%), Gaps = 16/209 (8%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP + RY K +G+G G V + T+ G+ VA+K + P+ + E Sbjct 244 DPKKKYTRYEK----IGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINE 294 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +++ L + +I+ + E L +VMEY+ GSL D + + AQ+ ++ Sbjct 295 ILVMKELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCREC 352 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066 + + +LHA IHRD+ + NVLL + VK+ DFG A+ PE + R + Sbjct 353 LQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 408 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095 W APE + + D+WS G+ E++ Sbjct 409 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 437 Score = 37.7 bits (86), Expect = 0.78, Method: Compositional matrix adjust. Identities = 49/215 (23%), Positives = 90/215 (42%), Gaps = 26/215 (12%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719 +M ++ + ++ + G E +V EY+ G L DV +A V ++ Sbjct 297 VMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIA---AVCRECL 353 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777 AL +L ++H ++ N+LL EG+ +KL+D G A E+ +R Sbjct 354 QALEFLHANQVIHRDIKSDNVLLG----MEGS---VKLTD--FGFCAQITPEQSKRSTMV 404 Query 778 ----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---- 829 W+APE + A +D W G +E+ +GE P + +P + Sbjct 405 GTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNGTP 461 Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + + PE P ++CL + +R S + +L+ Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496 >sp|P93050|RKF3_ARATH Probable LRR receptor-like serine/threonine-protein kinase RKF3 OS=Arabidopsis thaliana OX=3702 GN=RKF3 PE=2 SV=1 Length=617 Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 87/298 (29%), Positives = 138/298 (46%), Gaps = 56/298 (19%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G +G V DGT VA K K +C + + E++++ ++ H +++ Sbjct 289 IGRGGYGNV---FKGALPDGT--QVAFKRFK-NCSAGGDANFAHEVEVIASIRHVNLLAL 342 Query 963 KGCCED----QGEKSLQLVMEYVPLGSLRDYL-------------PRHSIGLAQLLLFAQ 1005 +G C +G + + +V + V GSL D+L R ++G+A+ Sbjct 343 RGYCTATTPYEGHQRI-IVCDLVSNGSLHDHLFGDLEAQLAWPLRQRIALGMAR------ 395 Query 1006 QICEGMAYLH--AQ-HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 G+AYLH AQ IHRD+ A N+LLD K+ DFGLAK PEG + R G Sbjct 396 ----GLAYLHYGAQPSIIHRDIKASNILLDERFEAKVADFGLAKFNPEGMTHMSTRVAGT 451 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQG 1117 + + APE + SDV+SFGV L ELL+ D P + +A Sbjct 452 --MGYVAPEYALYGQLTEKSDVYSFGVVLLELLSRRKAIVTDEEGQP-------VSVADW 502 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEV---YHLMKN-CWETEASFRPTFENLIPILKT 1171 +++R + L+ E P+K P EV Y L+ C + RPT + ++ +L++ Sbjct 503 AWSLVREGQTLDVVED-GMPEKGPPEVLEKYVLIAVLCSHPQLHARPTMDQVVKMLES 559 >sp|Q8AXB4|PAK3_XENLA Serine/threonine-protein kinase PAK 3 OS=Xenopus laevis OX=8355 GN=pak3 PE=2 SV=1 Length=564 Score = 84.0 bits (206), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 71/262 (27%), Positives = 117/262 (45%), Gaps = 25/262 (10%) Query 836 PSCPQLATLTSQCLT-YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894 P PQ S T Y T R ++ + D L+ L +++V DP + Sbjct 238 PVTPQPENSNSSTSTLYRNTDRQRKKSKMTDEEILE--KLRSIVSV------GDPKKKYT 289 Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R+ K +G+G G V Y + TG+ VA+K + P+ + EI ++R Sbjct 290 RFEK----IGQGASGTV----YTAIDIATGQEVAIKQMNLQQQPK-KELIINEILVMREN 340 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYL 1014 + +I+ Y E L +VMEY+ GSL D + + Q+ ++ + + +L Sbjct 341 KNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFL 398 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 H+ IHRD+ + N+LL D VK+ DFG A+ PE + R +W APE + Sbjct 399 HSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK----RSTMVGTPYWMAPEVV 454 Query 1074 KEYKFYYASDVWSFGVTLYELL 1095 + D+WS G+ E++ Sbjct 455 TRKAYGPKVDIWSLGIMAIEMV 476 Score = 34.3 bits (77), Expect = 9.3, Method: Compositional matrix adjust. Identities = 40/150 (27%), Positives = 64/150 (43%), Gaps = 26/150 (17%) Query 680 GPENIMVTEYVEHGPL-DVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736 G E +V EY+ G L DV + G + V ++ AL +L + ++H ++ Sbjct 355 GDELWVVMEYLAGGSLTDVVTETCMDEGQI-----AAVCRECLQALDFLHSNQVIHRDIK 409 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANS 790 NILL G +KL+D G A E+ +R W+APE + A Sbjct 410 SDNILL-------GMDGSVKLTD--FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-- 458 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +D W G +E+ +GE P + +P Sbjct 459 YGPKVDIWSLGIMAIEMV-EGEPPYLNENP 487 >sp|P51839|GUC2D_RAT Guanylate cyclase 2D OS=Rattus norvegicus OX=10116 GN=Gucy2d PE=1 SV=2 Length=1110 Score = 85.1 bits (209), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 76/272 (28%), Positives = 122/272 (45%), Gaps = 31/272 (11%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 GE V +K +A P R + +R + HE++ + G G + +V+E+ Sbjct 577 GEWVWLKKFEAGTAPDLRPSSLSLLRKMREMRHENVTAFLGLF--VGPEVSAMVLEHCAR 634 Query 984 GSLRDYLPRHSIGL-----AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 GSL D L + L A LLL + G+ YLH +H+ H L +RN ++D ++K Sbjct 635 GSLEDLLRNEDLRLDWTFKASLLL---DLIRGLRYLHHRHFPHGRLKSRNCVVDTRFVLK 691 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK-------EYKFYYASDVWSFGVTL 1091 I D G A+ + E H +R + + W APE L+ K + DV+S G+ L Sbjct 692 ITDHGYAEFL-ESHCSFR-PQPAPEELLWTAPELLRGPRRPWGPGKATFKGDVFSLGIIL 749 Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 E+LT + PP L + + ++ L PD+ P E LM+ C Sbjct 750 QEVLT-----RDPPYCSWGL----SAEEIIRKVASPPPLCRPLVSPDQGPLECIQLMQLC 800 Query 1152 WETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183 WE RP+ + + K+++ QG+ SV Sbjct 801 WEEAPDDRPSLDQIYTQFKSIN---QGKKTSV 829 Score = 40.0 bits (92), Expect = 0.17, Method: Compositional matrix adjust. Identities = 57/222 (26%), Positives = 86/222 (39%), Gaps = 32/222 (14%) Query 662 MSQVSHTHLAFVHGVCVRGPE-NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 M ++ H ++ G+ V GPE + MV E+ G L+ LR E + +K + L Sbjct 604 MREMRHENVTAFLGLFV-GPEVSAMVLEHCARGSLEDLLRNEDLRLDWTFKASLLLDLIR 662 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-----EERVER 775 L YL +++ HG + RN ++ T +K++D G S + E Sbjct 663 GLRYLHHRHFPHGRLKSRNCVV-------DTRFVLKITDHGYAEFLESHCSFRPQPAPEE 715 Query 776 IPWLAPECL-----PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 + W APE L P G + D + G L E+ + P S S +E R+ Sbjct 716 LLWTAPELLRGPRRPWGPGKATFKGDVFSLGIILQEV-LTRDPPYCSWGLSAEEII--RK 772 Query 831 HRLPEPSCPQLAT----------LTSQCLTYEPTQRPSFRTI 862 P P C L + L C P RPS I Sbjct 773 VASPPPLCRPLVSPDQGPLECIQLMQLCWEEAPDDRPSLDQI 814 >sp|Q17850|PK1_CAEEL Serine/threonine-protein kinase pak-1 OS=Caenorhabditis elegans OX=6239 GN=pak-1 PE=1 SV=2 Length=572 Score = 84.0 bits (206), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 59/205 (29%), Positives = 97/205 (47%), Gaps = 18/205 (9%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R +K+ +G G G V Y T VA+K + P+ + EI ++R Sbjct 293 RKYRKVDKIGSGASGSV----YTAIEISTEAEVAIKQMNLKDQPK-KELIINEILVMREN 347 Query 955 YHEHIIKYKG---CCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011 H +I+ Y C++ L +VMEY+ GSL D + + + +++ + + Sbjct 348 KHANIVNYLDSYLVCDE-----LWVVMEYLAGGSLTDVVTECQMEDGIIAAVCREVLQAL 402 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVFWYAP 1070 +LH++H IHRD+ + N+LL D VK+ DFG A+ PE R R +W AP Sbjct 403 EFLHSRHVIHRDIKSDNILLGMDGSVKLTDFGFCAQLSPE----QRKRTTMVGTPYWMAP 458 Query 1071 ECLKEYKFYYASDVWSFGVTLYELL 1095 E + ++ DVWS G+ E++ Sbjct 459 EVVTRKQYGPKVDVWSLGIMAIEMV 483 Score = 37.4 bits (85), Expect = 0.91, Method: Compositional matrix adjust. Identities = 31/112 (28%), Positives = 53/112 (47%), Gaps = 16/112 (14%) Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER- 772 V +++ AL +L +++++H ++ NILL G +KL+D G LS E+R Sbjct 394 VCREVLQALEFLHSRHVIHRDIKSDNILL-------GMDGSVKLTDFGF-CAQLSPEQRK 445 Query 773 ----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 V W+APE + +D W G +E+ +GE P + +P Sbjct 446 RTTMVGTPYWMAPEVV--TRKQYGPKVDVWSLGIMAIEMV-EGEPPYLNENP 494 >sp|C0LGH2|Y1561_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g56130 OS=Arabidopsis thaliana OX=3702 GN=At1g56130 PE=2 SV=2 Length=1032 Score = 84.7 bits (208), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 67/208 (32%), Positives = 99/208 (48%), Gaps = 32/208 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG V N G +VAVK L Q + + EI + ++ H +++K Sbjct 700 LGEGGFGPVY-----KGNLNDGRVVAVKLLSVGS-RQGKGQFVAEIVAISSVLHRNLVKL 753 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLR-----------DYLPRHSIGLAQLLLFAQQICEGM 1011 GCC +GE + LV EY+P GSL D+ R+ I L + G+ Sbjct 754 YGCCF-EGEHRM-LVYEYLPNGSLDQALFGDKTLHLDWSTRYEICLG--------VARGL 803 Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 YLH + +HRD+ A N+LLD+ + +I DFGLAK + + R G + + Sbjct 804 VYLHEEASVRIVHRDVKASNILLDSRLVPQISDFGLAKLYDDKKTHISTRVAG--TIGYL 861 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLT 1096 APE +DV++FGV EL++ Sbjct 862 APEYAMRGHLTEKTDVYAFGVVALELVS 889 Score = 43.9 bits (102), Expect = 0.011, Method: Compositional matrix adjust. Identities = 55/209 (26%), Positives = 88/209 (42%), Gaps = 32/209 (15%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K+L F +S V H +L ++G C G ++V EY+ +G LD Sbjct 719 VAVKLLSVGSRQGKGQFVAEIVAISSVLHRNLVKLYGCCFEGEHRMLVYEYLPNGSLDQA 778 Query 699 LRRERG-HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILL-ARLGLAEGTSP 753 L ++ H+ + + + +A L YL + +VH +V NILL +RL Sbjct 779 LFGDKTLHLDWSTRYEICLGVARGLVYLHEEASVRIVHRDVKASNILLDSRL-------- 830 Query 754 FIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 ++SD GL L +++ I +LAPE G L+ D + FG LE Sbjct 831 VPQISD--FGLAKLYDDKKTHISTRVAGTIGYLAPEYAMRG--HLTEKTDVYAFGVVALE 886 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 L S P+ E+ + + L E Sbjct 887 --------LVSGRPNSDENLEEEKKYLLE 907 >sp|Q5SUV5|MYLK4_MOUSE Myosin light chain kinase family member 4 OS=Mus musculus OX=10090 GN=Mylk4 PE=1 SV=2 Length=386 Score = 82.8 bits (203), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 66/202 (33%), Positives = 103/202 (51%), Gaps = 24/202 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG+V + TG +A K +K G + + K EI ++ L H ++I+ Sbjct 113 LGGGRFGQV----HKCEEKATGLKLAAKIIKTR-GAKDKEDVKNEISVMNQLDHVNLIQL 167 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020 E + + + LVM+ V G L D + + L +L +LF +QICEG+ Y+H + + Sbjct 168 YDAFESKHD--IILVMD-VEGGELFDRIIDENCNLTELDTILFMKQICEGIRYMHQMYIL 224 Query 1021 HRDLAARNVLLDN--DRLVKIGDFGLAKAVPEGHEYYRVRE----DGDSPVFWYAPECLK 1074 H DL N+L N + +KI DFGLA+ Y+ RE + +P F APE + Sbjct 225 HLDLKPENILCVNRDAKQIKIIDFGLAR-------RYKPREKLKVNFGTPEF-LAPEVVN 276 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 +++D+WS GV Y LL+ Sbjct 277 YDFVSFSTDMWSVGVITYMLLS 298 >sp|Q03147|CDK7_MOUSE Cyclin-dependent kinase 7 OS=Mus musculus OX=10090 GN=Cdk7 PE=1 SV=2 Length=346 Score = 82.0 bits (201), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 72/234 (31%), Positives = 111/234 (47%), Gaps = 27/234 (12%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ----EID 949 KRY +K+ LGEG F V Y + T ++VA+K +K + + G + EI Sbjct 10 KRY-EKLDFLGEGQFATV----YKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIK 64 Query 950 ILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQ 1006 +L+ L H +II G + G KS + LV +++ L + +S+ L + + + Sbjct 65 LLQELSHPNII---GLLDAFGHKSNISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLM 120 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 +G+ YLH +HRDL N+LLD + ++K+ DFGLAK+ + Y Sbjct 121 TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAY----THQVVTR 176 Query 1067 WY-APECLKEYKFY-YASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIG 1113 WY APE L + Y D+W+ G L ELL DS T+ E +G Sbjct 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLG 230 >sp|C0LGD9|Y1756_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g07560 OS=Arabidopsis thaliana OX=3702 GN=At1g07560 PE=1 SV=1 Length=871 Score = 84.3 bits (207), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 63/201 (31%), Positives = 101/201 (50%), Gaps = 13/201 (6%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LG+G FG V Y +GT E VAVK L ++ +K E+++L +YH +++ Sbjct 574 RVLGKGGFGMV----YHGYINGTEE-VAVKLLSPSSAQGYKE-FKTEVELLLRVYHTNLV 627 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQ-- 1017 G C+++ L L+ +Y+ G L+ + SI L A G+ YLH Sbjct 628 SLVGYCDEKDH--LALIYQYMVNGDLKKHFSGSSIISWVDRLNIAVDAASGLEYLHIGCK 685 Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRD+ + N+LLD+ K+ DFGL+++ P G E + V + E + Sbjct 686 PLIVHRDVKSSNILLDDQLQAKLADFGLSRSFPIGDESH-VSTLVAGTFGYLDHEYYQTN 744 Query 1077 KFYYASDVWSFGVTLYELLTH 1097 + SDV+SFGV L E++T+ Sbjct 745 RLSEKSDVYSFGVVLLEIITN 765 Score = 39.3 bits (90), Expect = 0.28, Method: Compositional matrix adjust. Identities = 53/189 (28%), Positives = 78/189 (41%), Gaps = 24/189 (13%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G G E V +K+L PS F L+ +V HT+L + G C ++ +Y Sbjct 587 GYINGTE-EVAVKLLSPSSAQGYKEFKTEVELLLRVYHTNLVSLVGYCDEKDHLALIYQY 645 Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLAR 744 + +G L + G ++W ++ +A AS L YL +VH +V NILL Sbjct 646 MVNGDLK---KHFSGSSIISWVDRLNIAVDAASGLEYLHIGCKPLIVHRDVKSSNILLDD 702 Query 745 LGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP-----WLAPECLPGGANSLSTAMDKW 798 A KL+D G+ + E V + +L E N LS D + Sbjct 703 QLQA-------KLADFGLSRSFPIGDESHVSTLVAGTFGYLDHEYYQ--TNRLSEKSDVY 753 Query 799 GFGATLLEI 807 FG LLEI Sbjct 754 SFGVVLLEI 762 >sp|P50613|CDK7_HUMAN Cyclin-dependent kinase 7 OS=Homo sapiens OX=9606 GN=CDK7 PE=1 SV=1 Length=346 Score = 82.0 bits (201), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 72/234 (31%), Positives = 112/234 (48%), Gaps = 27/234 (12%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ----EID 949 KRY +K+ LGEG F V Y + T ++VA+K +K + + G + EI Sbjct 10 KRY-EKLDFLGEGQFATV----YKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIK 64 Query 950 ILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQ 1006 +L+ L H +II G + G KS + LV +++ L + +S+ L + + + Sbjct 65 LLQELSHPNII---GLLDAFGHKSNISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLM 120 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 +G+ YLH +HRDL N+LLD + ++K+ DFGLAK+ + Y + Sbjct 121 TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQ----VVTR 176 Query 1067 WY-APECLKEYKFY-YASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIG 1113 WY APE L + Y D+W+ G L ELL DS T+ E +G Sbjct 177 WYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLG 230 >sp|Q9LPZ3|Y1141_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g11410 OS=Arabidopsis thaliana OX=3702 GN=At1g11410 PE=3 SV=3 Length=845 Score = 84.3 bits (207), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 72/205 (35%), Positives = 101/205 (49%), Gaps = 24/205 (12%) Query 903 LGEGHFGKVSLYCYDPTNDG---TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG G FG P G G +AVK L G Q +K E+ ++ L H ++ Sbjct 529 LGAGGFG--------PVYKGVLQNGMEIAVKRLSKSSG-QGMEEFKNEVKLISKLQHRNL 579 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYL 1014 ++ GCC + EK LV EY+P SL DY H A+L + + I G+ YL Sbjct 580 VRILGCCVEFEEK--MLVYEYLPNKSL-DYFIFHEEQRAELDWPKRMGIIRGIGRGILYL 636 Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 H IHRDL A NVLLDN+ + KI DFGLA+ + G++ + +PE Sbjct 637 HQDSRLRIIHRDLKASNVLLDNEMIPKIADFGLAR-IFGGNQIEGSTNRVVGTYGYMSPE 695 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 + +F SDV+SFGV + E++T Sbjct 696 YAMDGQFSIKSDVYSFGVLILEIIT 720 Score = 46.6 bits (109), Expect = 0.002, Method: Compositional matrix adjust. Identities = 52/228 (23%), Positives = 96/228 (42%), Gaps = 32/228 (14%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +LS + T ++ +L G G +G + + G E+ V K L S Sbjct 512 ELSTIATATNNFAFQNKLGAGGFGPVYKGVLQN----------GMEIAV--KRLSKSSGQ 559 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 F L+S++ H +L + G CV E ++V EY+ + LD ++ E + W Sbjct 560 GMEEFKNEVKLISKLQHRNLVRILGCCVEFEEKMLVYEYLPNKSLDYFIFHEEQRAELDW 619 Query 711 --KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763 +M + + + + YL + ++H ++ N+LL + K++D G+ Sbjct 620 PKRMGIIRGIGRGILYLHQDSRLRIIHRDLKASNVLLDNEMIP-------KIADFGLARI 672 Query 764 LGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 G E R+ +++PE G S+ + D + FG +LEI Sbjct 673 FGGNQIEGSTNRVVGTYGYMSPEYAMDGQFSIKS--DVYSFGVLILEI 718 >sp|A8X0C4|PAR4_CAEBR Serine/threonine-protein kinase par-4 OS=Caenorhabditis briggsae OX=6238 GN=par-4 PE=3 SV=2 Length=649 Score = 84.0 bits (206), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 61/205 (30%), Positives = 102/205 (50%), Gaps = 19/205 (9%) Query 903 LGEGHFGKVS--LYCYDPTNDGTGEMVAVKALKADCGPQHRSGW---KQEIDILRTLYHE 957 +G G +GKV + Y T A K +K + + +GW + E+ ILR L H Sbjct 203 IGTGSYGKVKEVIDIYTITRR------AAKIMKYEKLRKIPNGWDNIRSEMSILRRLNHR 256 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYL 1014 +I+K + + ++ EY +GS+++ + P H + + + ++C G+ YL Sbjct 257 NIVKLIEVFNLPEKGKVYMIFEYC-IGSVQNLIDMEPAHRLSIGESHAIFLELCHGLNYL 315 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL- 1073 H++ H+D+ N+LL D VKI DFG+A+ + R + +P F PEC+ Sbjct 316 HSKRVSHKDIKPGNLLLSIDMTVKICDFGVAEQICLFQSDGRCTKVNGTPKFQ-PPECVY 374 Query 1074 --KEYKFYYASDVWSFGVTLYELLT 1096 EY Y D+WS GVTLY +++ Sbjct 375 GNHEYFDGYKVDMWSAGVTLYNMVS 399 >sp|C0LGG8|Y5343_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g53430 OS=Arabidopsis thaliana OX=3702 GN=At1g53430 PE=1 SV=1 Length=1038 Score = 84.7 bits (208), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 73/244 (30%), Positives = 113/244 (46%), Gaps = 38/244 (16%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG V G +AVK L + +R + EI ++ L H +++K Sbjct 675 IGEGGFGPVYKGVL-----ADGMTIAVKQLSSKSKQGNRE-FVTEIGMISALQHPNLVKL 728 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLR-------------DYLPRHSIGLAQLLLFAQQICE 1009 GCC + K L LV EY+ SL D+ R+ I + I + Sbjct 729 YGCCIEG--KELLLVYEYLENNSLARALFGTEKQRLHLDWSTRNKICIG--------IAK 778 Query 1010 GMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G+AYLH + +HRD+ A NVLLD KI DFGLAK + + + R G + Sbjct 779 GLAYLHEESRLKIVHRDIKATNVLLDLSLNAKISDFGLAKLNDDENTHISTRIAG--TIG 836 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIG---IAQGQMTVL 1122 + APE +DV+SFGV E+++ +++ P +F+ L+ + Q Q ++L Sbjct 837 YMAPEYAMRGYLTDKADVYSFGVVCLEIVSGKSNTNYRPKEEFVYLLDWAYVLQEQGSLL 896 Query 1123 RLTE 1126 L + Sbjct 897 ELVD 900 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 68/270 (25%), Positives = 111/270 (41%), Gaps = 48/270 (18%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 + + +K L F ++S + H +L ++G C+ G E ++V EY+E+ L Sbjct 692 MTIAVKQLSSKSKQGNREFVTEIGMISALQHPNLVKLYGCCIEGKELLLVYEYLENNSLA 751 Query 697 VWL---RRERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEG 750 L ++R H+ + + + +A L+YL ++ +VH ++ N+LL L L Sbjct 752 RALFGTEKQRLHLDWSTRNKICIGIAKGLAYLHEESRLKIVHRDIKATNVLL-DLSLNAK 810 Query 751 TSPFIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGAT 803 S F GL L+ +E I ++APE G L+ D + FG Sbjct 811 ISDF--------GLAKLNDDENTHISTRIAGTIGYMAPEYAMRGY--LTDKADVYSFGVV 860 Query 804 LLEICFDGEAPLQSRSPSEK-------EHFYQRQHRLPEPSCPQLATLTSQ--------- 847 LEI G++ R P E+ + Q Q L E P L T S+ Sbjct 861 CLEIV-SGKSNTNYR-PKEEFVYLLDWAYVLQEQGSLLELVDPDLGTSFSKKEAMRMLNI 918 Query 848 ---CLTYEPTQRP---SFRTILRDLTRLQP 871 C PT RP S ++L ++QP Sbjct 919 ALLCTNPSPTLRPPMSSVVSMLEGKIKVQP 948 >sp|Q9R0G8|NRK_MOUSE Nik-related protein kinase OS=Mus musculus OX=10090 GN=Nrk PE=1 SV=2 Length=1455 Score = 84.7 bits (208), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 79/301 (26%), Positives = 131/301 (44%), Gaps = 56/301 (19%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-------------QHRSGWK-- 945 + +G G +G++ L ++ TG +VAVK + A P Q GW+ Sbjct 29 KAIGLGTYGRIFLGIHE----KTGSLVAVKVMSARKTPLPEIGRRVRVNKYQKSVGWRYS 84 Query 946 -------QEIDILRTL-YHEHIIKYKGCCEDQG----EKSLQLVMEYVPLGSLRDYLP-- 991 E+++LR +H++I+ + G + L +VME GS+ D + Sbjct 85 DEEEDLRTELNLLRKYSFHKNIVTFYGAFFKLNPPGHQHQLWMVMELCAAGSVTDVVRMT 144 Query 992 -RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 S+ + ++I +G+A+LHA IHRD+ +NVLL +D VKI DFG++ V Sbjct 145 RNQSLKEDWIAYICREILQGLAHLHAHQVIHRDIKGQNVLLTHDAEVKIVDFGVSAQVSR 204 Query 1051 GHEYYRVREDGDSPVFWYAPECLK-----EYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + R +W APE + + Y SDVWS G+T E+ + +PP Sbjct 205 TNGR---RNSFIGTPYWMAPEVIHCDEDPRCSYDYRSDVWSVGITAIEM-----AEGAPP 256 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L+ + + +LR + R + + M+NC FRPT N+ Sbjct 257 LCKLQPL---EALCVILREAAPKVKSSGWSR------KFQNFMENCMIKNFLFRPTSGNM 307 Query 1166 I 1166 + Sbjct 308 L 308 Score = 37.0 bits (84), Expect = 1.7, Method: Compositional matrix adjust. Identities = 46/200 (23%), Positives = 74/200 (37%), Gaps = 29/200 (15%) Query 632 DRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 D ++LR L +L S H + FY ++ H H + MV E Sbjct 85 DEEEDLRTELNLLRKYSFHKNIVTFYGAFFKLNPPGHQHQLW------------MVMELC 132 Query 691 EHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 G + +R R + W + +++ L++L ++H ++ G+N+LL Sbjct 133 AAGSVTDVVRMTRNQSLKEDWIAYICREILQGLAHLHAHQVIHRDIKGQNVLLTH----- 187 Query 750 GTSPFIKLSDPGVGLGALSREERVERIP----WLAPE---CLPGGANSLSTAMDKWGFGA 802 +K+ D GV R W+APE C S D W G Sbjct 188 --DAEVKIVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIHCDEDPRCSYDYRSDVWSVGI 245 Query 803 TLLEICFDGEAPLQSRSPSE 822 T +E+ +G PL P E Sbjct 246 TAIEMA-EGAPPLCKLQPLE 264 >sp|Q6I5Q6|RK185_ORYSJ Receptor-like cytoplasmic kinase 185 OS=Oryza sativa subsp. japonica OX=39947 GN=RLCK185 PE=1 SV=1 Length=491 Score = 83.2 bits (204), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 69/202 (34%), Positives = 102/202 (50%), Gaps = 17/202 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG+V Y N G+ VAVK L + G Q + E+ +L L+H++++ Sbjct 86 LGEGGFGRV--YKGHLEN---GQAVAVKQLDRN-GLQGNREFLVEVLMLSLLHHDNLVNL 139 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 G C D G++ L LV E++PLGSL D+L + + + A +G+ +LH + Sbjct 140 IGYCAD-GDQRL-LVYEFMPLGSLEDHLHDIPPDKEPLDWNTRMKIAAGAAKGLEFLHDK 197 Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 I+RD + N+LL K+ DFGLAK P G + + V + APE Sbjct 198 ANPPVIYRDFKSSNILLGEGYHPKLSDFGLAKLGPVGDKTH-VSTRVMGTYGYCAPEYAM 256 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + SDV+SFGV EL+T Sbjct 257 TGQLTVKSDVYSFGVVFLELIT 278 >sp|A8R7E6|CERK1_ARATH Chitin elicitor receptor kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CERK1 PE=1 SV=1 Length=617 Score = 84.0 bits (206), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 81/288 (28%), Positives = 130/288 (45%), Gaps = 40/288 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FG V Y + GE A+K + + Q + E+ +L ++H ++++ Sbjct 328 IGQGGFGAV-YYA-----ELRGEKAAIKKMDMEASKQ----FLAELKVLTRVHHVNLVRL 377 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018 G C E SL LV EYV G+L +L R + + + A G+ Y+H Sbjct 378 IGYCV---EGSLFLVYEYVENGNLGQHLHGSGREPLPWTKRVQIALDSARGLEYIHEHTV 434 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075 Y+HRD+ + N+L+D K+ DFGL K G R G F Y APE + Sbjct 435 PVYVHRDIKSANILIDQKFRAKVADFGLTKLTEVGGSATR----GAMGTFGYMAPETVYG 490 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV----LRLTELLERG 1131 + DV++FGV LYEL+ S++ K E +G +G + V + T+ E Sbjct 491 -EVSAKVDVYAFGVVLYELI----SAKGAVVKMTEAVGEFRGLVGVFEESFKETDKEEAL 545 Query 1132 ERLPRP---DKCPCEVYHLM----KNCWETEASFRPTFENLIPILKTV 1172 ++ P D P + + M K C + A RP+ ++ L T+ Sbjct 546 RKIIDPRLGDSYPFDSVYKMAELGKACTQENAQLRPSMRYIVVALSTL 593 Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust. Identities = 60/247 (24%), Positives = 101/247 (41%), Gaps = 44/247 (18%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F ++++V H +L + G CV G +V EYVE+G L L G P+ W ++ Sbjct 359 FLAELKVLTRVHHVNLVRLIGYCVEGSL-FLVYEYVENGNLGQHLHGS-GREPLPWTKRV 416 Query 713 VVAQQLASALSYLENKNL---VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LG 765 +A A L Y+ + VH ++ NIL+ + A K++D G+ +G Sbjct 417 QIALDSARGLEYIHEHTVPVYVHRDIKSANILIDQKFRA-------KVADFGLTKLTEVG 469 Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC---------------FD 810 + + ++APE + G +S +D + FG L E+ F Sbjct 470 GSATRGAMGTFGYMAPETVYG---EVSAKVDVYAFGVVLYELISAKGAVVKMTEAVGEFR 526 Query 811 GEAPL--QSRSPSEKEHFYQR------QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 G + +S ++KE ++ P S ++A L C RPS R I Sbjct 527 GLVGVFEESFKETDKEEALRKIIDPRLGDSYPFDSVYKMAELGKACTQENAQLRPSMRYI 586 Query 863 LRDLTRL 869 + L+ L Sbjct 587 VVALSTL 593 >sp|Q9NWZ3|IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 OS=Homo sapiens OX=9606 GN=IRAK4 PE=1 SV=1 Length=460 Score = 83.2 bits (204), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 68/202 (34%), Positives = 98/202 (49%), Gaps = 19/202 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--DCGPQH-RSGWKQEIDILRTLYHEHI 959 +GEG FG V + T VAVK L A D + + + QEI ++ HE++ Sbjct 192 MGEGGFGVVYKGYVNNTT------VAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENL 245 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLH 1015 ++ G D + L LV Y+P GSL D L + AQ G+ +LH Sbjct 246 VELLGFSSDGDD--LCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLH 303 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLK 1074 H+IHRD+ + N+LLD KI DFGLA+A + R G + + APE L+ Sbjct 304 ENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTA--YMAPEALR 361 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + SD++SFGV L E++T Sbjct 362 G-EITPKSDIYSFGVVLLEIIT 382 Score = 57.0 bits (136), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 54/243 (22%), Positives = 104/243 (43%), Gaps = 33/243 (14%) Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 ++D + ++ F + +M++ H +L + G G + +V Y+ +G L L Sbjct 218 MVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCL 277 Query 703 RGHVPMAWKM--VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G P++W M +AQ A+ +++L + +H ++ NILL A K+SD Sbjct 278 DGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTA-------KISDF 330 Query 761 GVGLGA--LSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ + ++ RI ++APE L G ++ D + FG LLEI A Sbjct 331 GLARASEKFAQTVMTSRIVGTTAYMAPEALRG---EITPKSDIYSFGVVLLEIITGLPAV 387 Query 815 LQSRSPS---------------EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859 + R P +++ ++ + S + ++ SQCL + +RP Sbjct 388 DEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDI 447 Query 860 RTI 862 + + Sbjct 448 KKV 450 >sp|O80623|Y2393_ARATH Probable receptor-like protein kinase At2g39360 OS=Arabidopsis thaliana OX=3702 GN=At2g39360 PE=1 SV=1 Length=815 Score = 84.3 bits (207), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 67/205 (33%), Positives = 101/205 (49%), Gaps = 26/205 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHEHI 959 +G G FGKV Y E VAVK PQ R G +K E+++L H H+ Sbjct 493 IGVGGFGKV----YKGVLRDKTE-VAVKR----GAPQSRQGLAEFKTEVEMLTQFRHRHL 543 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQLLLFAQQICEGMAY 1013 + G C++ E + +V EY+ G+L+D+L PR S Q L G+ Y Sbjct 544 VSLIGYCDENSE--MIIVYEYMEKGTLKDHLYDLDDKPRLS--WRQRLEICVGAARGLHY 599 Query 1014 LHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 LH + IHRD+ + N+LLD++ + K+ DFGL+K P+ + + V + P Sbjct 600 LHTGSTRAIIHRDVKSANILLDDNFMAKVADFGLSKTGPDLDQTH-VSTAVKGSFGYLDP 658 Query 1071 ECLKEYKFYYASDVWSFGVTLYELL 1095 E L + SDV+SFGV + E++ Sbjct 659 EYLTRQQLTEKSDVYSFGVVMLEVV 683 Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust. Identities = 57/236 (24%), Positives = 94/236 (40%), Gaps = 29/236 (12%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F +++Q H HL + G C E I+V EY+E G L L ++W ++ Sbjct 528 FKTEVEMLTQFRHRHLVSLIGYCDENSEMIIVYEYMEKGTLKDHLYDLDDKPRLSWRQRL 587 Query 713 VVAQQLASALSYL---ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 + A L YL + ++H +V NILL +A+ LS G L Sbjct 588 EICVGAARGLHYLHTGSTRAIIHRDVKSANILLDDNFMAKVAD--FGLSKTGPDLDQTHV 645 Query 770 EERVE-RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 V+ +L PE L L+ D + FG +LE+ G + P EK + + Sbjct 646 STAVKGSFGYLDPEYLT--RQQLTEKSDVYSFGVVMLEVVC-GRPVIDPSLPREKVNLIE 702 Query 829 ------RQHRLPEPSCPQLA------------TLTSQCLTYEPTQRPSFRTILRDL 866 ++ +L + P L +T +CL+ +RP+ +L +L Sbjct 703 WAMKLVKKGKLEDIIDPFLVGKVKLEEVKKYCEVTEKCLSQNGIERPAMGDLLWNL 758 >sp|A9S5R3|M2K1C_PHYPA Mitogen-activated protein kinase kinase 1c OS=Physcomitrium patens OX=3218 GN=MKK1c PE=3 SV=1 Length=346 Score = 81.6 bits (200), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 77/286 (27%), Positives = 134/286 (47%), Gaps = 24/286 (8%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ +R LG+G G V L + TN A+KA++ + R QE+ I + + Sbjct 70 LELVRFLGKGAGGTVQLVRHKWTNVN----YALKAIQMNINETVRKQIVQELKINQVTHQ 125 Query 957 E--HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAY 1013 + +I++ G + +++EY+ GSL D + + I L + A Q+ +G+ Y Sbjct 126 QCPYIVECFHSFYHNG--VISMILEYMDRGSLSDIIKQQKQIPEPYLAVIASQVLKGLEY 183 Query 1014 LH-AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 LH +H IHRD+ N+L+++ VKI DFG++ + R+ + +PE Sbjct 184 LHQVRHIIHRDIKPSNLLINHKGEVKISDFGVSAVLVHS---LAQRDTFVGTCTYMSPER 240 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE-LLERG 1131 L+ + Y SD+WS G+TL E C P + G+ +G L E ++ + Sbjct 241 LQGRSYAYDSDLWSLGLTLLE----CALGTFP----YKPAGMEEGWQNFFILMECIVNQP 292 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEK 1175 PDK E +++C S RP+ +L+ P L+ +E+ Sbjct 293 PAAASPDKFSPEFCSFIESCIRKCPSERPSTTDLLKHPFLQKYNEE 338 Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 50/198 (25%), Positives = 89/198 (45%), Gaps = 32/198 (16%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN-KNLVHGNVCGRNILLA 743 M+ EY++ G L +++++ +P + V+A Q+ L YL ++++H ++ N+L+ Sbjct 145 MILEYMDRGSLSDIIKQQK-QIPEPYLAVIASQVLKGLEYLHQVRHIIHRDIKPSNLLIN 203 Query 744 RLGLAEGTSPFIKLSDPGVGLGAL----SREERVERIPWLAPECLPGGANSLSTAMDKWG 799 G +K+SD GV + R+ V +++PE L G S + D W Sbjct 204 HKGE-------VKISDFGVSAVLVHSLAQRDTFVGTCTYMSPERLQG--RSYAYDSDLWS 254 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-------------PEPSCPQLATLTS 846 G TLLE C G P + P+ E +Q L P+ P+ + Sbjct 255 LGLTLLE-CALGTFPYK---PAGMEEGWQNFFILMECIVNQPPAAASPDKFSPEFCSFIE 310 Query 847 QCLTYEPTQRPSFRTILR 864 C+ P++RPS +L+ Sbjct 311 SCIRKCPSERPSTTDLLK 328 >sp|Q8LST2|WNK7_ARATH Probable serine/threonine-protein kinase WNK7 OS=Arabidopsis thaliana OX=3702 GN=WNK7 PE=2 SV=1 Length=557 Score = 83.6 bits (205), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 73/276 (26%), Positives = 132/276 (48%), Gaps = 26/276 (9%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD---CG 937 +P+ DPT RY++ +G+G K +D + G VA ++ D Sbjct 15 DPEVLEIDPTC---RYIRYKEVIGKGA-SKTVFKGFDEVD---GIEVAWNQVRIDDLLQS 67 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIG 996 P E+ +L++L H++II++ D K++ ++ E GSLR Y +H + Sbjct 68 PDCLERLYSEVRLLKSLKHKNIIRFYNSWIDDKNKTVNIITELFTSGSLRQYRKKHRKVN 127 Query 997 LAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFGLAKAVPEGHE 1053 + + +A+QI G+ YLH+Q IHRD+ N+ ++ N VKIGD GLA + + + Sbjct 128 MKAVKCWARQILTGLKYLHSQDPPIIHRDIKCDNIFINGNHGEVKIGDLGLATVMEQANA 187 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFL 1109 + +P F APE E + +D++SFG+ + E++T +C+ S Sbjct 188 KSVI----GTPEFM-APELYDE-NYNELADIYSFGMCMLEMVTFEYPYCECRNSAQIYKK 241 Query 1110 ELIGIAQGQMTVLRLTELLERGER--LPRPDKCPCE 1143 GI ++ ++ E+++ E+ LP ++ E Sbjct 242 VSSGIKPASLSKVKDPEVMKFIEKCLLPASERLSAE 277 >sp|P47735|RLK5_ARATH Receptor-like protein kinase 5 OS=Arabidopsis thaliana OX=3702 GN=RLK5 PE=1 SV=1 Length=999 Score = 84.3 bits (207), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 63/191 (33%), Positives = 92/191 (48%), Gaps = 20/191 (10%) Query 924 GEMVAVKALKADC---------GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 GE+VAVK L +R + E++ L T+ H+ I++ CC G+ L Sbjct 705 GEVVAVKKLNKSVKGGDDEYSSDSLNRDVFAAEVETLGTIRHKSIVRLWCCCS-SGDCKL 763 Query 975 QLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAA 1026 LV EY+P GSL D L +G + L A EG++YLH +HRD+ + Sbjct 764 -LVYEYMPNGSLADVLHGDRKGGVVLGWPERLRIALDAAEGLSYLHHDCVPPIVHRDVKS 822 Query 1027 RNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 N+LLD+D K+ DFG+AK G + + APE + + SD++ Sbjct 823 SNILLDSDYGAKVADFGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEKSDIY 882 Query 1086 SFGVTLYELLT 1096 SFGV L EL+T Sbjct 883 SFGVVLLELVT 893 >sp|O04086|Y1105_ARATH Probable receptor-like protein kinase At1g11050 OS=Arabidopsis thaliana OX=3702 GN=At1g11050 PE=2 SV=1 Length=625 Score = 84.0 bits (206), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 73/268 (27%), Positives = 118/268 (44%), Gaps = 25/268 (9%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGC--CEDQGEKSLQLVMEYV 981 G ++AVK + + Q + ++ E++I+ L H +++ +GC +D E LV +Y+ Sbjct 317 GSVIAVKKV-IESEFQGDAEFRNEVEIISNLKHRNLVPLRGCSMVDDDSESQRYLVYDYM 375 Query 982 PLGSLRDYL-PRHS-----IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLD 1032 G+L D+L PR + Q + +G+AYLH HRD+ N+LLD Sbjct 376 SNGNLDDHLFPRGETTKMPLSWPQRKSIILDVAKGLAYLHYGVKPAIYHRDIKGTNILLD 435 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 D ++ DFGLAK EG + R G + APE + SDV+SFGV + Sbjct 436 VDMRARVADFGLAKQSREGESHLTTRVAGTHG--YLAPEYALYGQLTEKSDVYSFGVVIL 493 Query 1093 ELLTHCD----SSQSPPTKFL------ELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 E++ S+ P FL L+ + + L + L E G L P Sbjct 494 EIMCGRKALDLSTSGSPNTFLITDWAWSLVKAGKTE-EALEQSLLREEGSGLSNPKGIME 552 Query 1143 EVYHLMKNCWETEASFRPTFENLIPILK 1170 + C + RPT + + +L+ Sbjct 553 RFLQVGILCAHVLVALRPTILDALKMLE 580 >sp|Q08942|NRKA_TRYBB Putative serine/threonine-protein kinase A OS=Trypanosoma brucei brucei OX=5702 GN=NRKA PE=2 SV=1 Length=431 Score = 82.8 bits (203), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 81/292 (28%), Positives = 127/292 (43%), Gaps = 52/292 (18%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ-EIDILRT 953 +YL K +G G +G+ Y + DG+ + K + Q + Q EI L Sbjct 19 KYLNK-GIVGLGSYGEA--YVAESVEDGS--LCVAKVMDLSKMSQRDKRYAQSEIKCLAN 73 Query 954 LYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIGLAQ-------LLLFAQ 1005 H +II+Y ED E L +VME+ G+L + + G A+ L LF Q Sbjct 74 CNHPNIIRY---IEDHEENDRLLIVMEFADSGNLDEQIKLRGSGDARYFQEHEALFLFLQ 130 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 +C + Y+H+ +HRD+ + NVLL + LVK+GDFG + H+Y ED S V Sbjct 131 -LCLALDYIHSHKMLHRDIKSANVLLTSTGLVKLGDFGFS------HQY----EDTVSGV 179 Query 1066 ---------FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 ++ APE ++ +DVWS GV LYE++ P L G+ Sbjct 180 VASTFCGTPYYLAPELWNNKRYNKKADVWSLGVLLYEIM-----GMKKPFSASNLKGL-- 232 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 ++++L G P PD E ++ + + RP+ + I Sbjct 233 -------MSKVLA-GTYAPLPDSFSSEFKRVVDGILVADPNDRPSVREIFQI 276 >sp|Q92241|PHO85_KLULA Negative regulator of the PHO system OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=PHO85 PE=3 SV=2 Length=304 Score = 80.9 bits (198), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 59/208 (28%), Positives = 100/208 (48%), Gaps = 20/208 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 K++ +G G + V Y N TG VA+K +K D S +EI +++ L H Sbjct 7 FKQLEKVGNGTYATV----YKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKH 62 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFAQQICE 1009 ++I++ E L LV E++ L+ ++ + G + + F Q+ + Sbjct 63 DNIVRLFDVI--HTENKLTLVFEFMD-NDLKKFMDNRNKGNSHKGLEMDLVKYFQWQLLQ 119 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068 G+A+ H +HRDL +N+L++N +K+GDFGLA+A + + WY Sbjct 120 GVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIPVNTFS----SEVVTLWYR 175 Query 1069 APECLKEYKFYYAS-DVWSFGVTLYELL 1095 AP+ L + Y S D+WS G L E++ Sbjct 176 APDVLMGSRNYCTSIDIWSCGCILAEMI 203 Score = 41.2 bits (95), Expect = 0.043, Method: Compositional matrix adjust. Identities = 65/304 (21%), Positives = 116/304 (38%), Gaps = 50/304 (16%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--VLD 645 + QL +G GT VY+G + G + V LK LD Sbjct 6 QFKQLEKVGNGTYATVYKGLNKTTG------------------------VYVALKEVKLD 41 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + A E SLM ++ H ++ + V + +V E++++ R +G+ Sbjct 42 SEEGTPSTAIREI-SLMKELKHDNIVRLFDVIHTENKLTLVFEFMDNDLKKFMDNRNKGN 100 Query 706 VPMAWKMVVAQ----QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 +M + + QL +++ ++H ++ +N+L+ G +KL D G Sbjct 101 SHKGLEMDLVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQ-------LKLGDFG 153 Query 762 V----GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + G+ + V + + AP+ L G N T++D W G L E+ S Sbjct 154 LARAFGIPVNTFSSEVVTLWYRAPDVLMGSRN-YCTSIDIWSCGCILAEMIMGKPLFPGS 212 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 + + + E + PQ+ +Q Y P P RDL +L +N +V Sbjct 213 NDEEQLKLIFDTMGTPVEQTWPQV----TQLAKYNPLLPPHMP---RDLKQLLQNNTEEV 265 Query 878 LTVN 881 L N Sbjct 266 LDDN 269 >sp|Q9LEU7|CIPK5_ARATH CBL-interacting serine/threonine-protein kinase 5 OS=Arabidopsis thaliana OX=3702 GN=CIPK5 PE=1 SV=1 Length=445 Score = 82.8 bits (203), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 68/208 (33%), Positives = 104/208 (50%), Gaps = 23/208 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD---CGPQHRSGWKQEIDILRTLYHE 957 R LG+G F KV Y GE VA+K + D P K+EI I++ + H Sbjct 16 RLLGKGTFAKV----YYGKEIIGGECVAIKVINKDQVMKRPGMMEQIKREISIMKLVRHP 71 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +I++ K + + + VME+V G L + + + + QQ+ + Y H++ Sbjct 72 NIVELKEVMATKTK--IFFVMEFVKGGELFCKISKGKLHEDAARRYFQQLISAVDYCHSR 129 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG------DSPVFWYAPE 1071 HRDL N+LLD + +KI DFGL+ A+PE ++ +DG +P + APE Sbjct 130 GVSHRDLKPENLLLDENGDLKISDFGLS-ALPE-----QILQDGLLHTQCGTPAY-VAPE 182 Query 1072 CLKEYKFYYA-SDVWSFGVTLYELLTHC 1098 LK+ + A +D+WS GV LY LL C Sbjct 183 VLKKKGYDGAKADIWSCGVVLYVLLAGC 210 Score = 43.9 bits (102), Expect = 0.008, Method: Compositional matrix adjust. Identities = 52/214 (24%), Positives = 88/214 (41%), Gaps = 22/214 (10%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M V H ++ + V + V E+V+ G L + + + H A + QQL Sbjct 63 SIMKLVRHPNIVELKEVMATKTKIFFVMEFVKGGELFCKISKGKLHEDAARRYF--QQLI 120 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776 SA+ Y ++ + H ++ N+LL G +K+SD GL AL + + + Sbjct 121 SAVDYCHSRGVSHRDLKPENLLLDENGD-------LKISD--FGLSALPEQILQDGLLHT 171 Query 777 -----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQ 830 ++APE L + A D W G L + G P Q + + ++ Sbjct 172 QCGTPAYVAPEVLKKKGYDGAKA-DIWSCGVVLY-VLLAGCLPFQDENLMNMYRKIFRAD 229 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 P P+ L S+ L +P +R S I+R Sbjct 230 FEFPPWFSPEARRLISKLLVVDPDRRISIPAIMR 263 >sp|Q9Z1W9|STK39_MOUSE STE20/SPS1-related proline-alanine-rich protein kinase OS=Mus musculus OX=10090 GN=Stk39 PE=1 SV=1 Length=556 Score = 83.6 bits (205), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 75/256 (29%), Positives = 116/256 (45%), Gaps = 24/256 (9%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 E VA+K + + +EI + H +++ Y + E L LVM+ + G Sbjct 99 ERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDE--LWLVMKLLSGG 156 Query 985 SLRDYLP------RHSIGLAQLLLFA---QQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035 S+ D + H G+ + + A +++ EG+ YLH IHRDL A N+LL D Sbjct 157 SMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDG 216 Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092 V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T Sbjct 217 SVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAI 276 Query 1093 ELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERG-ERLPRPDKCPCEVYHLMKN 1150 EL T + PP K L L T+ LE G E K L+ Sbjct 277 ELATGAAPYHKYPPMKVLML--------TLQNDPPTLETGVEDKEMMKKYGKSFRKLLSL 328 Query 1151 CWETEASFRPTFENLI 1166 C + + S RPT L+ Sbjct 329 CLQKDPSKRPTAAELL 344 Score = 40.0 bits (92), Expect = 0.16, Method: Compositional matrix adjust. Identities = 53/227 (23%), Positives = 89/227 (39%), Gaps = 30/227 (13%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWL------RRERGHVPMAWKMVV 714 MSQ SH ++ + V E +V + + G LD+ + G + A + Sbjct 125 MSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATI 184 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALSRE 770 +++ L YL +H ++ NILL G + G S F L+ G R+ Sbjct 185 LKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAF--LATGGDVTRNKVRK 242 Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------LQS 817 V W+APE + D W FG T +E+ G AP LQ+ Sbjct 243 TFVGTPCWMAPEVME-QVRGYDFKADMWSFGITAIELA-TGAAPYHKYPPMKVLMLTLQN 300 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 P+ + ++ + + L S CL +P++RP+ +L+ Sbjct 301 DPPTLETGVEDKE--MMKKYGKSFRKLLSLCLQKDPSKRPTAAELLK 345 >sp|O14427|CLA4_CANAX Serine/threonine-protein kinase CLA4 OS=Candida albicans OX=5476 GN=CLA4 PE=3 SV=1 Length=971 Score = 84.3 bits (207), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 58/204 (28%), Positives = 100/204 (49%), Gaps = 10/204 (5%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 K + + G+G G V L N+ +A+K + D P+ + EI +++ Sbjct 677 KPLFRIVEKAGQGASGNVYLAEMIKDNN---RKIAIKQMDLDAQPR-KELIINEILVMKD 732 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGM 1011 H++I+ + G+ L ++MEY+ GSL + + + L Q+ + +G+ Sbjct 733 SQHKNIVNFLDSYL-IGDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIATICFETLKGL 791 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 +LH +H IHRD+ + NVLLD VKI DFG + + R G +P +W APE Sbjct 792 QHLHKKHIIHRDIKSDNVLLDAYGNVKITDFGFCAKLTD-QRNKRATMVG-TP-YWMAPE 848 Query 1072 CLKEYKFYYASDVWSFGVTLYELL 1095 +K+ ++ DVWS G+ E++ Sbjct 849 VVKQKEYDEKVDVWSLGIMTIEMI 872 Score = 35.8 bits (81), Expect = 3.4, Method: Compositional matrix adjust. Identities = 34/167 (20%), Positives = 67/167 (40%), Gaps = 19/167 (11%) Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 +M H ++ F+ + E ++ EY++ G L + + + + Sbjct 729 VMKDSQHKNIVNFLDSYLIGDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIATICFETL 788 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777 L +L K+++H ++ N+LL G +K++D G A ++R +R Sbjct 789 KGLQHLHKKHIIHRDIKSDNVLLDAYG-------NVKITD--FGFCAKLTDQRNKRATMV 839 Query 778 ----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 W+APE + +D W G +E+ +GE P + P Sbjct 840 GTPYWMAPEVV--KQKEYDEKVDVWSLGIMTIEM-IEGEPPYLNEEP 883 >sp|Q54B33|PAKE_DICDI Serine/threonine-protein kinase pakE OS=Dictyostelium discoideum OX=44689 GN=pakE PE=3 SV=1 Length=926 Score = 84.3 bits (207), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 54/194 (28%), Positives = 101/194 (52%), Gaps = 12/194 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G +G V + TN +A+K L P ++EID+L+ +++ Y Sbjct 656 LGQGGYGAVFKVLHRETNFP----LAIKVLS--ITPTRIKDIEKEIDLLKKCRCPNVLSY 709 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G + + L ++M++ +GS+ D + ++ Q+ + + G+ YLH++ + Sbjct 710 YGSISSKLTE-LWILMDHCAVGSINDMMKICCDTLDEEQIAVVTLNVLNGLGYLHSKGIV 768 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 H D+ A N+LL D+ +KI DFG+++ + EY + SP++ APE + + + Sbjct 769 HLDVKAANILLTEDKQIKIADFGVSQQL--QTEYGQANVYIGSPLYM-APEVILKAPYNS 825 Query 1081 ASDVWSFGVTLYEL 1094 +D+WS G+TL EL Sbjct 826 KADIWSLGITLIEL 839 Score = 39.7 bits (91), Expect = 0.23, Method: Compositional matrix adjust. Identities = 42/166 (25%), Positives = 66/166 (40%), Gaps = 32/166 (19%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 VV + + L YL +K +VH +V NILL IK++D GV L E Sbjct 750 VVTLNVLNGLGYLHSKGIVHLDVKAANILLTE-------DKQIKIADFGVS-QQLQTEYG 801 Query 773 VERI-----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 + ++APE + ++ D W G TL+E+ + R P+ Sbjct 802 QANVYIGSPLYMAPEVILKAP--YNSKADIWSLGITLIELA-------EGRPPNRGLRSM 852 Query 828 QRQHRLPEPSCPQLA----------TLTSQCLTYEPTQRPSFRTIL 863 + +P P+L+ + CL +P QRPS +L Sbjct 853 NQLVEIPNMPPPKLSNPKDWSPCFNNFLATCLVKDPVQRPSVIDLL 898 >sp|Q5APR8|CLA4_CANAL Serine/threonine-protein kinase CLA4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=CLA4 PE=1 SV=1 Length=976 Score = 84.3 bits (207), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 57/198 (29%), Positives = 98/198 (49%), Gaps = 10/198 (5%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + G+G G V L N+ +A+K + D P+ + EI +++ H++I Sbjct 688 VEKAGQGASGNVYLAEMIKDNN---RKIAIKQMDLDAQPR-KELIINEILVMKDSQHKNI 743 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQ 1017 + + G+ L ++MEY+ GSL + + + L Q+ + +G+ +LH + Sbjct 744 VNFLDSYL-IGDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIATICFETLKGLQHLHKK 802 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 H IHRD+ + NVLLD VKI DFG + + R G +P +W APE +K+ + Sbjct 803 HIIHRDIKSDNVLLDAYGNVKITDFGFCAKLTD-QRNKRATMVG-TP-YWMAPEVVKQKE 859 Query 1078 FYYASDVWSFGVTLYELL 1095 + DVWS G+ E++ Sbjct 860 YDEKVDVWSLGIMTIEMI 877 Score = 35.8 bits (81), Expect = 3.2, Method: Compositional matrix adjust. Identities = 34/167 (20%), Positives = 67/167 (40%), Gaps = 19/167 (11%) Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 +M H ++ F+ + E ++ EY++ G L + + + + Sbjct 734 VMKDSQHKNIVNFLDSYLIGDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIATICFETL 793 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-- 777 L +L K+++H ++ N+LL G +K++D G A ++R +R Sbjct 794 KGLQHLHKKHIIHRDIKSDNVLLDAYG-------NVKITD--FGFCAKLTDQRNKRATMV 844 Query 778 ----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 W+APE + +D W G +E+ +GE P + P Sbjct 845 GTPYWMAPEVV--KQKEYDEKVDVWSLGIMTIEM-IEGEPPYLNEEP 888 >sp|Q9UEW8|STK39_HUMAN STE20/SPS1-related proline-alanine-rich protein kinase OS=Homo sapiens OX=9606 GN=STK39 PE=1 SV=3 Length=545 Score = 83.6 bits (205), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 62/200 (31%), Positives = 98/200 (49%), Gaps = 15/200 (8%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 E VA+K + + +EI + H +++ Y + E L LVM+ + G Sbjct 87 ERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDE--LWLVMKLLSGG 144 Query 985 SLRDYLP------RHSIGLAQLLLFA---QQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035 S+ D + H G+ + + A +++ EG+ YLH IHRDL A N+LL D Sbjct 145 SMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDG 204 Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092 V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T Sbjct 205 SVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAI 264 Query 1093 ELLTHCDS-SQSPPTKFLEL 1111 EL T + PP K L L Sbjct 265 ELATGAAPYHKYPPMKVLML 284 Score = 39.7 bits (91), Expect = 0.17, Method: Compositional matrix adjust. Identities = 53/227 (23%), Positives = 89/227 (39%), Gaps = 30/227 (13%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWL------RRERGHVPMAWKMVV 714 MSQ SH ++ + V E +V + + G LD+ + G + A + Sbjct 113 MSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATI 172 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALSRE 770 +++ L YL +H ++ NILL G + G S F L+ G R+ Sbjct 173 LKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAF--LATGGDVTRNKVRK 230 Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------LQS 817 V W+APE + D W FG T +E+ G AP LQ+ Sbjct 231 TFVGTPCWMAPEVME-QVRGYDFKADMWSFGITAIELA-TGAAPYHKYPPMKVLMLTLQN 288 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 P+ + ++ + + L S CL +P++RP+ +L+ Sbjct 289 DPPTLETGVEDKE--MMKKYGKSFRKLLSLCLQKDPSKRPTAAELLK 333 >sp|O88506|STK39_RAT STE20/SPS1-related proline-alanine-rich protein kinase OS=Rattus norvegicus OX=10116 GN=Stk39 PE=1 SV=2 Length=553 Score = 83.6 bits (205), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 75/256 (29%), Positives = 116/256 (45%), Gaps = 24/256 (9%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 E VA+K + + +EI + H +++ Y + E L LVM+ + G Sbjct 96 ERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDE--LWLVMKLLSGG 153 Query 985 SLRDYLP------RHSIGLAQLLLFA---QQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035 S+ D + H G+ + + A +++ EG+ YLH IHRDL A N+LL D Sbjct 154 SMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDG 213 Query 1036 LVKIGDFGLAKAVPEGHEYYR--VREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLY 1092 V+I DFG++ + G + R VR+ W APE +++ + Y + +D+WSFG+T Sbjct 214 SVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAI 273 Query 1093 ELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERG-ERLPRPDKCPCEVYHLMKN 1150 EL T + PP K L L T+ LE G E K L+ Sbjct 274 ELATGAAPYHKYPPMKVLML--------TLQNDPPTLETGVEDKEMMKKYGKSFRKLLSL 325 Query 1151 CWETEASFRPTFENLI 1166 C + + S RPT L+ Sbjct 326 CLQKDPSKRPTAAELL 341 Score = 39.7 bits (91), Expect = 0.17, Method: Compositional matrix adjust. Identities = 53/227 (23%), Positives = 89/227 (39%), Gaps = 30/227 (13%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP-LDVWL------RRERGHVPMAWKMVV 714 MSQ SH ++ + V E +V + + G LD+ + G + A + Sbjct 122 MSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATI 181 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALSRE 770 +++ L YL +H ++ NILL G + G S F L+ G R+ Sbjct 182 LKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAF--LATGGDVTRNKVRK 239 Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP-------------LQS 817 V W+APE + D W FG T +E+ G AP LQ+ Sbjct 240 TFVGTPCWMAPEVME-QVRGYDFKADMWSFGITAIELA-TGAAPYHKYPPMKVLMLTLQN 297 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 P+ + ++ + + L S CL +P++RP+ +L+ Sbjct 298 DPPTLETGVEDKE--MMKKYGKSFRKLLSLCLQKDPSKRPTAAELLK 342 >sp|F4JEQ2|PBL23_ARATH Probable serine/threonine-protein kinase PBL23 OS=Arabidopsis thaliana OX=3702 GN=PBL23 PE=2 SV=1 Length=386 Score = 82.0 bits (201), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 68/203 (33%), Positives = 100/203 (49%), Gaps = 17/203 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG+V Y + ++VAVK L + G Q + E+ +L L+H++++ Sbjct 88 LGEGGFGRV----YKGQIETPEQVVAVKQLDRN-GYQGNREFLVEVMMLSLLHHQNLVNL 142 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQLLLFAQQICEGMAYLHA 1016 G C D G++ + LV EY+ GSL D+L + + + A G+ YLH Sbjct 143 VGYCAD-GDQRI-LVYEYMQNGSLEDHLLELARNKKKPLDWDTRMKVAAGAARGLEYLHE 200 Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 I+RD A N+LLD + K+ DFGLAK P G E + V + APE Sbjct 201 TADPPVIYRDFKASNILLDEEFNPKLSDFGLAKVGPTGGETH-VSTRVMGTYGYCAPEYA 259 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 + SDV+SFGV E++T Sbjct 260 LTGQLTVKSDVYSFGVVFLEMIT 282 Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 66/262 (25%), Positives = 107/262 (41%), Gaps = 40/262 (15%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD-- 696 V +K LD + + F ++S + H +L + G C G + I+V EY+++G L+ Sbjct 108 VAVKQLDRNGYQGNREFLVEVMMLSLLHHQNLVNLVGYCADGDQRILVYEYMQNGSLEDH 167 Query 697 -VWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEG 750 + L R + P+ W +M VA A L YL +++ + NIL L E Sbjct 168 LLELARNKKK-PLDWDTRMKVAAGAARGLEYLHETADPPVIYRDFKASNIL-----LDEE 221 Query 751 TSPFIKLSDPGVG-LGALSREERVE-RIPWLAPECLPGGA--NSLSTAMDKWGFGATLLE 806 +P KLSD G+ +G E V R+ C P A L+ D + FG LE Sbjct 222 FNP--KLSDFGLAKVGPTGGETHVSTRVMGTYGYCAPEYALTGQLTVKSDVYSFGVVFLE 279 Query 807 ICFDGEAPLQSRSPSEKEH--------FYQRQH-----------RLPEPSCPQLATLTSQ 847 + G + + P+E+++ F R+ + P Q + + Sbjct 280 M-ITGRRVIDTTKPTEEQNLVTWASPLFKDRRKFTLMADPLLEGKYPIKGLYQALAVAAM 338 Query 848 CLTYEPTQRPSFRTILRDLTRL 869 CL E RP ++ L L Sbjct 339 CLQEEAATRPMMSDVVTALEYL 360 >sp|Q12263|GIN4_YEAST Serine/threonine-protein kinase GIN4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=GIN4 PE=1 SV=1 Length=1142 Score = 84.3 bits (207), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 73/217 (34%), Positives = 103/217 (47%), Gaps = 38/217 (18%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGW---------------KQ 946 LG G GKV L N TG+ AVK + KA + SG ++ Sbjct 25 LGLGSTGKVQL----ARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDALPYGIER 80 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL------RDYLPRHSIGLAQL 1000 EI I++ L H ++++ E + L LV+EY G L R LP H + Sbjct 81 EIIIMKLLNHPNVLRLYDVWETNTD--LYLVLEYAEKGELFNLLVERGPLPEH-----EA 133 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 + F +QI G++Y HA +HRDL N+LLD+ +KI DFG+A EG ++ E Sbjct 134 IRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEG----KLLET 189 Query 1061 GDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLT 1096 + APE + + +ASDVWS GV L+ LLT Sbjct 190 SCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLT 226 >sp|A8X5H5|GSK3_CAEBR Glycogen synthase kinase-3 OS=Caenorhabditis briggsae OX=6238 GN=gsk-3 PE=3 SV=1 Length=359 Score = 81.6 bits (200), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 69/209 (33%), Positives = 103/209 (49%), Gaps = 35/209 (17%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V L TN EMVA+K + D ++R E+ I+R L H +I+K Sbjct 42 IGNGSFGVVFLAKLSTTN----EMVAIKKVLQDKRFKNR-----ELQIMRKLNHPNIVKL 92 Query 963 KGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRH------SIGLAQLLLFAQQICEGMA 1012 K G+K L L++EYVP R + RH SI + + L+ Q+ +A Sbjct 93 KYFFYSSGDKKDELYLNLILEYVPETVYR--VARHYSKQRQSIPMIYVKLYMYQLLRSLA 150 Query 1013 YLHAQHYIHRDLAARNVLLDNDR-LVKIGDFGLAKAVPEGHEYYRVREDGDSPV----FW 1067 Y+H+ HRD+ +N+L+D + ++K+ DFG AK Y VR + + ++ Sbjct 151 YIHSIGICHRDIKPQNLLIDPETGILKLCDFGSAK--------YLVRNEPNVSYICSRYY 202 Query 1068 YAPECLKEYKFYYAS-DVWSFGVTLYELL 1095 APE + Y S DVWS G + ELL Sbjct 203 RAPELIFGATNYTNSIDVWSAGTVIAELL 231 Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust. Identities = 65/323 (20%), Positives = 133/323 (41%), Gaps = 66/323 (20%) Query 573 TLNLSQLSFHRVDQK-EITQLSH--LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 T+ ++ ++ VDQ+ EI+ +G G+ V+ +L + + D+ Sbjct 17 TMVVASVATDGVDQQVEISYYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKVLQDK----- 71 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 R + +EL+++ K+ P+ + FY + ++ +++ + PE V Sbjct 72 -RFKNRELQIMRKLNHPNIVKLKYFFYSSGDKKDEL------YLNLILEYVPET--VYRV 122 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 H ++R +PM + + QL +L+Y+ + + H ++ +N+L+ + Sbjct 123 ARH------YSKQRQSIPMIYVKLYMYQLLRSLAYIHSIGICHRDIKPQNLLI------D 170 Query 750 GTSPFIKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGFGATLLE 806 + +KL D G + E V I + APE + G N + ++D W G + E Sbjct 171 PETGILKLCDFGSAKYLVRNEPNVSYICSRYYRAPELIFGATN-YTNSIDVWSAGTVIAE 229 Query 807 I-----CFDGEA------------------PLQSRSPSEKE--------HFYQRQHRLPE 835 + F G++ +QS +P+ KE H + + R+ Sbjct 230 LLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIQSMNPNYKEFKFPQIKAHPWNKVFRVHT 289 Query 836 PSCPQLATLTSQCLTYEPTQRPS 858 P+ + L S+ + Y PT RP+ Sbjct 290 PA--EAIDLISKIIEYTPTSRPT 310 >sp|Q8C078|KKCC2_MOUSE Calcium/calmodulin-dependent protein kinase kinase 2 OS=Mus musculus OX=10090 GN=Camkk2 PE=1 SV=2 Length=588 Score = 83.6 bits (205), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 52/150 (35%), Positives = 77/150 (51%), Gaps = 6/150 (4%) Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ 1005 QEI IL+ L H +++K +D E L +V E V G + + + Q + Q Sbjct 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQ 294 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 + +G+ YLH Q IHRD+ N+L+ D +KI DFG++ +G + G +P Sbjct 295 DLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF-KGSDALLSNTVG-TPA 352 Query 1066 FWYAPECLKEYKFYY---ASDVWSFGVTLY 1092 F APE L E + + A DVW+ GVTLY Sbjct 353 FM-APESLSETRKIFSGKALDVWAMGVTLY 381 >sp|Q15131|CDK10_HUMAN Cyclin-dependent kinase 10 OS=Homo sapiens OX=9606 GN=CDK10 PE=1 SV=1 Length=360 Score = 81.6 bits (200), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 70/214 (33%), Positives = 101/214 (47%), Gaps = 26/214 (12%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDI 950 + +K+ +GEG +G V Y + T E+VA+K ++ D + + G +EI + Sbjct 37 KEFEKLNRIGEGTYGIV----YRARDTQTDEIVALKKVRMD---KEKDGIPISSLREITL 89 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQIC 1008 L L H +I++ K +S+ LVM Y L SL + +P AQ+ Q+ Sbjct 90 LLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPT-PFSEAQVKCIVLQVL 148 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP---V 1065 G+ YLH IHRDL N+L+ + VK DFGLA+A Y V +P Sbjct 149 RGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARA-------YGVPVKPMTPKVVT 201 Query 1066 FWY-APECLKEYKFYYAS-DVWSFGVTLYELLTH 1097 WY APE L S D+W+ G L ELL H Sbjct 202 LWYRAPELLLGTTTQTTSIDMWAVGCILAELLAH 235 >sp|C0LGI2|Y1677_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g67720 OS=Arabidopsis thaliana OX=3702 GN=At1g67720 PE=1 SV=1 Length=929 Score = 84.3 bits (207), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 66/203 (33%), Positives = 98/203 (48%), Gaps = 17/203 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 + +G G FG V Y DG + VAVK + AD + E+ +L ++H +++ Sbjct 610 KKVGRGSFGSV---YYGRMKDG--KEVAVK-ITADPSSHLNRQFVTEVALLSRIHHRNLV 663 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA 1016 G CE+ + L V EY+ GSL D+L S + L AQ +G+ YLH Sbjct 664 PLIGYCEEADRRIL--VYEYMHNGSLGDHLHGSSDYKPLDWLTRLQIAQDAAKGLEYLHT 721 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRD+ + N+LLD + K+ DFGL++ E + V V + PE Sbjct 722 GCNPSIIHRDVKSSNILLDINMRAKVSDFGLSRQTEE--DLTHVSSVAKGTVGYLDPEYY 779 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 + SDV+SFGV L+ELL+ Sbjct 780 ASQQLTEKSDVYSFGVVLFELLS 802 Score = 56.6 bits (135), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 59/233 (25%), Positives = 101/233 (43%), Gaps = 45/233 (19%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 +G+G+ +VY GR++ G+E+ V + DPS H + Sbjct 612 VGRGSFGSVYYGRMK-----------------------DGKEVAVKITA-DPSSH-LNRQ 646 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F +L+S++ H +L + G C I+V EY+ +G L L + P+ W ++ Sbjct 647 FVTEVALLSRIHHRNLVPLIGYCEEADRRILVYEYMHNGSLGDHLHGSSDYKPLDWLTRL 706 Query 713 VVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA--- 766 +AQ A L YL N +++H +V NILL + K+SD G+ Sbjct 707 QIAQDAAKGLEYLHTGCNPSIIHRDVKSSNILL-------DINMRAKVSDFGLSRQTEED 759 Query 767 LSREERVER--IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 L+ V + + +L PE + L+ D + FG L E+ G+ P+ + Sbjct 760 LTHVSSVAKGTVGYLDPEYY--ASQQLTEKSDVYSFGVVLFEL-LSGKKPVSA 809 >sp|O13839|FIN1_SCHPO G2-specific protein kinase fin1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=fin1 PE=3 SV=1 Length=722 Score = 84.0 bits (206), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 75/307 (24%), Positives = 133/307 (43%), Gaps = 55/307 (18%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG++ Y G ++A K + + Q + E++ILR L H +I++ Sbjct 10 IGHGSFGRI----YKVQRLKDGALLAQKEIHFGNITRQEKQYIADEVNILRNLKHPNIVQ 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLH- 1015 Y G ++ + + L MEY G L + + R+ ++L F Q+ + H Sbjct 66 YCGEELNRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTEQEVLKFFTQLLLALYRCHY 125 Query 1016 ------------------AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 Q +HRD+ N+ LD + VK+GDFGL+K + + Sbjct 126 GENAPACDSQWPREIFHPKQSVLHRDIKPANIFLDENNSVKLGDFGLSKLLDNTRVF--T 183 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE--LLTHCDSSQSPPTKFLELI-GI 1114 + +P ++ +PE ++ + SDVW+ G ++E +LTH +S +LEL I Sbjct 184 QSYVGTP-YYMSPEIIRSSPYSAKSDVWALGCVIFEICMLTHPFEGRS----YLELQRNI 238 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTV 1172 QG ++ +V+ L+++C E + RPT L+ PIL + Sbjct 239 CQGNLSCW--------------DHHYSDDVFLLIRHCLEVNSDLRPTTYQLLRSPILSDI 284 Query 1173 HEKYQGQ 1179 K + + Sbjct 285 RSKLESE 291 >sp|O64778|Y1142_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61420 OS=Arabidopsis thaliana OX=3702 GN=At1g61420 PE=3 SV=2 Length=807 Score = 84.0 bits (206), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 68/204 (33%), Positives = 102/204 (50%), Gaps = 22/204 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG P G G+ +AVK L + G Q + + EI ++ L H+++ Sbjct 500 LGQGGFG--------PVYKGKLQDGKEIAVKRLSSSSG-QGKEEFMNEIVLISKLQHKNL 550 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015 ++ GCC +GE+ L L+ E++ SL +L R I + L Q I G+ YLH Sbjct 551 VRILGCCI-EGEEKL-LIYEFMLNNSLDTFLFDSRKRLEIDWPKRLDIIQGIARGIHYLH 608 Query 1016 AQHY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 + IHRDL N+LLD KI DFGLA+ + +G EY + + APE Sbjct 609 RDSHLKVIHRDLKVSNILLDEKMNPKISDFGLAR-MYQGTEYQDNTRRVVGTLGYMAPEY 667 Query 1073 LKEYKFYYASDVWSFGVTLYELLT 1096 F SD++SFGV + E+++ Sbjct 668 AWTGMFSEKSDIYSFGVLMLEIIS 691 >sp|Q552C6|ZAK2_DICDI Dual specificity protein kinase zak2 OS=Dictyostelium discoideum OX=44689 GN=zak2 PE=1 SV=1 Length=635 Score = 83.6 bits (205), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 124/524 (24%), Positives = 208/524 (40%), Gaps = 112/524 (21%) Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALSREERV 773 L LS+L ++H ++ NI+L + G+ + G+S + D G + S Sbjct 108 LTETLSFLHKHQILHRDIKPSNIILDKNGVLKLIDFGSSIIDQQQDDGDNICKESSFAIT 167 Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-------FDGEAPLQSRSPSEKEHF 826 ++APE + + D W G T+LEI FDG P+ Sbjct 168 GTHTYMAPEV--KKLHRSTKKSDVWSLGCTVLEIVGGNPKKIFDG-IPI----------- 213 Query 827 YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL--RDLTRLQPHNLADVLTVNP-- 882 +P + +CL +P +R +L R ++ + N + P Sbjct 214 ------IPNHVSEIMVDFIKRCLIIDPNKRSHMEELLTHRLISSMVGQNKNRENNIEPKF 267 Query 883 --DSPASD-PTVFHKRY-----------LKKIRDL---GEGHFGKVSLYCYDPTNDGTGE 925 D +S P F R+ LK +D G+G F V Y+ T Sbjct 268 NNDYLSSKFPERFAPRFEKPKWEIEFNELKFNKDDTVGGDGFFSVVKKGYYNETE----- 322 Query 926 MVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGCCE--DQGEKSLQLVMEYV 981 VA+K +K G + E+ I+ L H +I+++ C D E + +V E++ Sbjct 323 -VAIKLIKKAHGENVTVCDTFYHEVLIISNLRHPNIVQFIAACIKFDNKEVNHCIVSEWM 381 Query 982 PLGSLRDYLPRHSIGL-------AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL--- 1031 G+L ++ L ++LL I +GM Y H Q IHRDL + NVLL Sbjct 382 SGGNLSQFISNERKILEINPHLRVKILL---DIAKGMLYSHRQGIIHRDLTSNNVLLNFR 438 Query 1032 -----------------DNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 D+D ++ K+ DFGL+ E ++R G S + + APE L Sbjct 439 KKKLLNNNSSNNDEQFYDSDEIIAKVCDFGLSSNQSESK---KLR--GGS-IHYMAPENL 492 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 SD++SFG+ ++++ ++ SP T + + +M + E L + Sbjct 493 NGSPINEKSDIYSFGLLVWQMFSYA----SPNTIY------SPKEMASMVSDEKLNYRPQ 542 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPT-FENLIPILKTVHEKY 1176 +P P + L+ CW+ RP F +I LK +++ Y Sbjct 543 IPF--NVPLKFKELITQCWDRNPLNRPKDFSEIIDKLKDINQIY 584 Score = 54.7 bits (130), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 45/183 (25%), Positives = 84/183 (46%), Gaps = 34/183 (19%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV-PL 983 ++VAVK + + + E DIL + +I +Y ED + + + MEY+ Sbjct 40 DIVAVKIINK------KFFKRNETDILEKIRLFNIPRYYSHAED--DNYIYIYMEYIEDK 91 Query 984 GSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 LR ++++ + E +++LH +HRD+ N++LD + ++K+ DFG Sbjct 92 KQLR-------FKESEIISMIADLTETLSFLHKHQILHRDIKPSNIILDKNGVLKLIDFG 144 Query 1044 LAKAVPEGHEYYRVREDGDSPV-----------FWYAPECLKEYKFYYASDVWSFGVTLY 1092 + + ++DGD+ + APE K ++ SDVWS G T+ Sbjct 145 SSIIDQQ-------QDDGDNICKESSFAITGTHTYMAPEVKKLHRSTKKSDVWSLGCTVL 197 Query 1093 ELL 1095 E++ Sbjct 198 EIV 200 Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust. Identities = 51/266 (19%), Positives = 104/266 (39%), Gaps = 33/266 (12%) Query 635 QELRVVLKVLDPSHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPE----NIMVT 687 E V +K++ +H + + FY ++S + H ++ C++ + +V+ Sbjct 319 NETEVAIKLIKKAHGENVTVCDTFYHEVLIISNLRHPNIVQFIAACIKFDNKEVNHCIVS 378 Query 688 EYVEHGPLDVWLRRERGHVPMA--WKMVVAQQLASALSYLENKNLVHGNVCGRNILL--- 742 E++ G L ++ ER + + ++ + +A + Y + ++H ++ N+LL Sbjct 379 EWMSGGNLSQFISNERKILEINPHLRVKILLDIAKGMLYSHRQGIIHRDLTSNNVLLNFR 438 Query 743 -----------ARLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIPWLAPECLPGGANS 790 + K+ D G+ + S++ R I ++APE L G Sbjct 439 KKKLLNNNSSNNDEQFYDSDEIIAKVCDFGLSSNQSESKKLRGGSIHYMAPENLNGSP-- 496 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP-----QLATLT 845 ++ D + FG + ++ F +P SP E + P P + L Sbjct 497 INEKSDIYSFGLLVWQM-FSYASPNTIYSPKEMASMVSDEKLNYRPQIPFNVPLKFKELI 555 Query 846 SQCLTYEPTQRP-SFRTILRDLTRLQ 870 +QC P RP F I+ L + Sbjct 556 TQCWDRNPLNRPKDFSEIIDKLKDIN 581 >sp|O64477|Y2913_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At2g19130 OS=Arabidopsis thaliana OX=3702 GN=At2g19130 PE=2 SV=1 Length=828 Score = 84.0 bits (206), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 86/291 (30%), Positives = 132/291 (45%), Gaps = 37/291 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V ++D +AVK L+ Q ++ E+ + T+ H ++++ Sbjct 499 LGGGGFGSVFKGALPDSSD-----IAVKRLEGI--SQGEKQFRTEVVTIGTIQHVNLVRL 551 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLF--AQQICEGMAYLHA 1016 +G C +G K L LV +Y+P GSL +L I L L F A G+AYLH Sbjct 552 RGFCS-EGSKKL-LVYDYMPNGSLDSHLFLNQVEEKIVLGWKLRFQIALGTARGLAYLHD 609 Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + IH D+ N+LLD+ K+ DFGLAK V G ++ RV + APE + Sbjct 610 ECRDCIIHCDIKPENILLDSQFCPKVADFGLAKLV--GRDFSRVLTTMRGTRGYLAPEWI 667 Query 1074 KEYKFYYASDVWSFGVTLYELLT---HCDSSQSPPTKFL----ELIGIAQGQMTVL---R 1123 +DV+S+G+ L+EL++ + + S++ +F I G + L R Sbjct 668 SGVAITAKADVYSYGMMLFELVSGRRNTEQSENEKVRFFPSWAATILTKDGDIRSLVDPR 727 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 L E + R K C C + E S RP ++ IL+ V E Sbjct 728 LEGDAVDIEEVTRACKVACW-------CIQDEESHRPAMSQVVQILEGVLE 771 Score = 44.3 bits (103), Expect = 0.007, Method: Compositional matrix adjust. Identities = 53/212 (25%), Positives = 90/212 (42%), Gaps = 36/212 (17%) Query 640 VLKVLDPSHHDIALAFYETAS-----------LMSQVSHTHLAFVHGVCVRGPENIMVTE 688 V K P DIA+ E S + + H +L + G C G + ++V + Sbjct 507 VFKGALPDSSDIAVKRLEGISQGEKQFRTEVVTIGTIQHVNLVRLRGFCSEGSKKLLVYD 566 Query 689 YVEHGPLD--VWLRRERGHVPMAWKM--VVAQQLASALSYLENK---NLVHGNVCGRNIL 741 Y+ +G LD ++L + + + WK+ +A A L+YL ++ ++H ++ NIL Sbjct 567 YMPNGSLDSHLFLNQVEEKIVLGWKLRFQIALGTARGLAYLHDECRDCIIHCDIKPENIL 626 Query 742 LARLGLAEGTSPFI-KLSDPGVGLGALSREERVERI-----PWLAPECLPGGANSLSTAM 795 L S F K++D G+ RV +LAPE + G A ++ Sbjct 627 L--------DSQFCPKVADFGLAKLVGRDFSRVLTTMRGTRGYLAPEWISGVA--ITAKA 676 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 D + +G L E+ QS +EK F+ Sbjct 677 DVYSYGMMLFELVSGRRNTEQSE--NEKVRFF 706 >sp|O23304|BLUS1_ARATH Serine/threonine-protein kinase BLUS1 OS=Arabidopsis thaliana OX=3702 GN=BLUS1 PE=1 SV=1 Length=487 Score = 82.8 bits (203), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 53/186 (28%), Positives = 93/186 (50%), Gaps = 25/186 (13%) Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 +VA+KA+ D ++E + L H +I+ C ++ L +VM ++ GS Sbjct 41 VVAIKAIDLDQSRADFDSLRRETKTMSLLSHPNILN--AYCSFTVDRCLWVVMPFMSCGS 98 Query 986 LRDY--------LPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037 L LP + I + F ++ ++YLH Q ++HRD+ A N+L+D+D V Sbjct 99 LHSIVSSSFPSGLPENCISV-----FLKETLNAISYLHDQGHLHRDIKAGNILVDSDGSV 153 Query 1038 KIGDFGLAKAVPE--------GHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFG 1088 K+ DFG++ ++ E R+ + +P +W APE + + Y + +D+WSFG Sbjct 154 KLADFGVSASIYEPVTSSSGTTSSSLRLTDIAGTP-YWMAPEVVHSHTGYGFKADIWSFG 212 Query 1089 VTLYEL 1094 +T EL Sbjct 213 ITALEL 218 Score = 36.6 bits (83), Expect = 1.6, Method: Compositional matrix adjust. Identities = 44/181 (24%), Positives = 69/181 (38%), Gaps = 38/181 (21%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS---- 768 V ++ +A+SYL ++ +H ++ NIL+ G +KL+D GV Sbjct 118 VFLKETLNAISYLHDQGHLHRDIKAGNILVDSDG-------SVKLADFGVSASIYEPVTS 170 Query 769 ---------REERVERIP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 R + P W+APE + A D W FG T LE+ G PL Sbjct 171 SSGTTSSSLRLTDIAGTPYWMAPEVVHSHTGYGFKA-DIWSFGITALELAH-GRPPLSHL 228 Query 819 SP--------SEKEHFYQRQHRLPEPS-------CPQLATLTSQCLTYEPTQRPSFRTIL 863 P +++ HF + S + CL +PT+RPS +L Sbjct 229 PPLKSLLMKITKRFHFSDYEINTSGSSKKGNKKFSKAFREMVGLCLEQDPTKRPSAEKLL 288 Query 864 R 864 + Sbjct 289 K 289 >sp|Q86CS2|ATG1_DICDI Serine/threonine-protein kinase atg1 OS=Dictyostelium discoideum OX=44689 GN=atg1 PE=3 SV=1 Length=668 Score = 83.6 bits (205), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 58/203 (29%), Positives = 97/203 (48%), Gaps = 17/203 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK----ADCGPQHRSGWKQEIDILRTLYHEH 958 +G G F +V Y + T E A+K + AD + EI IL+ L H + Sbjct 13 IGWGAFAQV----YKGFSIKTNEPFAIKVVDVCRLADKNSKLTENLNYEIRILKELSHTN 68 Query 959 IIK-YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016 I++ Y E+ + ++ME G Y+ H + + L F +Q+ G+ +L Sbjct 69 IVRLYDVLNEETDPTFIYMIMECCEGGDFSKYIRTHKKLTEEKALYFMKQLANGLKFLRQ 128 Query 1017 QHYIHRDLAARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + +HRDL +N+LL +D ++KIGDFG AK + + + + + + APE L Sbjct 129 KQIVHRDLKPQNLLLSDDSEHPILKIGDFGFAKFI----DPFSLSDTFCGSPLYMAPEIL 184 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 + +D+WS G+ LYE+L Sbjct 185 HRKNYTVKADLWSVGIILYEMLV 207 Score = 41.2 bits (95), Expect = 0.058, Method: Compositional matrix adjust. Identities = 48/205 (23%), Positives = 86/205 (42%), Gaps = 15/205 (7%) Query 661 LMSQVSHTHLAFVHGVCVR--GPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQ 717 ++ ++SHT++ ++ V P I M+ E E G ++R + + + +Q Sbjct 60 ILKELSHTNIVRLYDVLNEETDPTFIYMIMECCEGGDFSKYIRTHK-KLTEEKALYFMKQ 118 Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVER 775 LA+ L +L K +VH ++ +N+LL+ + P +K+ D G + S + Sbjct 119 LANGLKFLRQKQIVHRDLKPQNLLLS----DDSEHPILKIGDFGFAKFIDPFSLSDTFCG 174 Query 776 IP-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRL 833 P ++APE L + + D W G L E+ GE S S P ++ +L Sbjct 175 SPLYMAPEIL--HRKNYTVKADLWSVGIILYEMLV-GEPAYNSGSVPDLLNQLQNKKIKL 231 Query 834 PEPSCPQLATLTSQCLTYEPTQRPS 858 P L L + +R S Sbjct 232 PSHISSDCQNLIYSLLQIDVEKRIS 256 >sp|C0LGH3|Y5614_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g56140 OS=Arabidopsis thaliana OX=3702 GN=At1g56140 PE=2 SV=2 Length=1033 Score = 84.0 bits (206), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 69/208 (33%), Positives = 98/208 (47%), Gaps = 32/208 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG V NDG VAVK L Q + + EI + + H +++K Sbjct 699 LGEGGFGPV---YKGKLNDG--REVAVKLLSVGS-RQGKGQFVAEIVAISAVQHRNLVKL 752 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLR-----------DYLPRHSIGLAQLLLFAQQICEGM 1011 GCC +GE L LV EY+P GSL D+ R+ I L + G+ Sbjct 753 YGCCY-EGEHRL-LVYEYLPNGSLDQALFGEKTLHLDWSTRYEICLG--------VARGL 802 Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 YLH + +HRD+ A N+LLD+ + K+ DFGLAK + + R G + + Sbjct 803 VYLHEEARLRIVHRDVKASNILLDSKLVPKVSDFGLAKLYDDKKTHISTRVAG--TIGYL 860 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLT 1096 APE +DV++FGV EL++ Sbjct 861 APEYAMRGHLTEKTDVYAFGVVALELVS 888 Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust. Identities = 63/236 (27%), Positives = 97/236 (41%), Gaps = 44/236 (19%) Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 G G +GK++D GR+ V +K+L F +S V H +L Sbjct 703 GFGPVYKGKLND------GRE------VAVKLLSVGSRQGKGQFVAEIVAISAVQHRNLV 750 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENK-- 728 ++G C G ++V EY+ +G LD L E+ H+ + + + +A L YL + Sbjct 751 KLYGCCYEGEHRLLVYEYLPNGSLDQALFGEKTLHLDWSTRYEICLGVARGLVYLHEEAR 810 Query 729 -NLVHGNVCGRNILLARLGLAEGTSPFI-KLSDPGVGLGALSREERVE-------RIPWL 779 +VH +V NILL S + K+SD GL L +++ I +L Sbjct 811 LRIVHRDVKASNILL--------DSKLVPKVSD--FGLAKLYDDKKTHISTRVAGTIGYL 860 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 APE G L+ D + FG LE L S P+ E+ + L E Sbjct 861 APEYAMRG--HLTEKTDVYAFGVVALE--------LVSGRPNSDENLEDEKRYLLE 906 >sp|Q9LUT0|CARK1_ARATH Receptor-like cytoplasmic kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CARK1 PE=1 SV=1 Length=364 Score = 81.6 bits (200), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 87/322 (27%), Positives = 138/322 (43%), Gaps = 38/322 (12%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRD-------LGEGHFGKVSLYCYDPTNDGT 923 P NL V+ + P S A+ P L+ I D +GEG +G+V + Sbjct 41 PKNLP-VIQMQPISVAAIPA----DELRDITDNYGSKSLIGEGSYGRVFYGILK-----S 90 Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 G+ A+K L D Q + ++ ++ L E+++ G C D + L EY P Sbjct 91 GKAAAIKKL--DSSKQPDQEFLAQVSMVSRLRQENVVALLGYCVDGPLRVL--AYEYAPN 146 Query 984 GSLRDYL----------PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVL 1030 GSL D L P + Q + A G+ YLH + H IHRD+ + NVL Sbjct 147 GSLHDILHGRKGVKGAQPGPVLSWHQRVKIAVGAARGLEYLHEKANPHVIHRDIKSSNVL 206 Query 1031 LDNDRLVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 L +D + KI DF L+ P+ + R G ++APE SDV+SFGV Sbjct 207 LFDDDVAKIADFDLSNQAPDMAARLHSTRVLGT--FGYHAPEYAMTGTLSTKSDVYSFGV 264 Query 1090 TLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148 L ELLT + P ++ A +++ ++ + ++ P K ++ + Sbjct 265 VLLELLTGRKPVDHTLPRGQQSVVTWATPKLSEDKVKQCVDARLNGEYPPKAVAKLAAVA 324 Query 1149 KNCWETEASFRPTFENLIPILK 1170 C + EA FRP ++ L+ Sbjct 325 ALCVQYEADFRPNMSIVVKALQ 346 Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 49/178 (28%), Positives = 82/178 (46%), Gaps = 17/178 (10%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRE--RGHVP---M 708 F S++S++ ++ + G CV GP ++ EY +G L D+ R+ +G P + Sbjct 109 FLAQVSMVSRLRQENVVALLGYCVDGPLRVLAYEYAPNGSLHDILHGRKGVKGAQPGPVL 168 Query 709 AW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 +W ++ +A A L YL N +++H ++ N+LL +A+ LS+ Sbjct 169 SWHQRVKIAVGAARGLEYLHEKANPHVIHRDIKSSNVLLFDDDVAKIAD--FDLSNQAPD 226 Query 764 LGALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 + A RV + APE G +LST D + FG LLE+ G P+ P Sbjct 227 MAARLHSTRVLGTFGYHAPEYAMTG--TLSTKSDVYSFGVVLLEL-LTGRKPVDHTLP 281 >sp|O88831|KKCC2_RAT Calcium/calmodulin-dependent protein kinase kinase 2 OS=Rattus norvegicus OX=10116 GN=Camkk2 PE=1 SV=1 Length=587 Score = 83.2 bits (204), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 52/150 (35%), Positives = 77/150 (51%), Gaps = 6/150 (4%) Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ 1005 QEI IL+ L H +++K +D E L +V E V G + + + Q + Q Sbjct 234 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQ 293 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 + +G+ YLH Q IHRD+ N+L+ D +KI DFG++ +G + G +P Sbjct 294 DLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF-KGSDALLSNTVG-TPA 351 Query 1066 FWYAPECLKEYKFYY---ASDVWSFGVTLY 1092 F APE L E + + A DVW+ GVTLY Sbjct 352 FM-APESLSETRKIFSGKALDVWAMGVTLY 380 >sp|O64771|Y1148_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61480 OS=Arabidopsis thaliana OX=3702 GN=At1g61480 PE=2 SV=2 Length=809 Score = 84.0 bits (206), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 68/201 (34%), Positives = 99/201 (49%), Gaps = 16/201 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V G+ +AVK L + G Q + + EI ++ L H+++++ Sbjct 502 LGQGGFGSVY-----KGKLQDGKEIAVKRLSSSSG-QGKEEFMNEIVLISKLQHKNLVRI 555 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017 GCC +GE+ L LV E++ SL +L R I + + I G+ YLH Sbjct 556 LGCC-IEGEERL-LVYEFLLNKSLDTFLFDSRKRLEIDWPKRFNIIEGIARGLHYLHRDS 613 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 IHRDL N+LLD KI DFGLA+ + +G EY + + APE Sbjct 614 CLRVIHRDLKVSNILLDEKMNPKISDFGLAR-MYQGTEYQDNTRRVAGTLGYMAPEYAWT 672 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 F SD++SFGV L E++T Sbjct 673 GMFSEKSDIYSFGVILLEIIT 693 >sp|O61661|CHK1_DROME Serine/threonine-protein kinase grp OS=Drosophila melanogaster OX=7227 GN=grp PE=1 SV=2 Length=512 Score = 82.8 bits (203), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 64/197 (32%), Positives = 100/197 (51%), Gaps = 14/197 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG +G+V L N TGE VA+K + P + ++E+ I + L +HI+++ Sbjct 28 LGEGAYGEVKLLI----NRQTGEAVAMKMVDLKKHPDAANSVRKEVCIQKMLQDKHILRF 83 Query 963 KGCCEDQGEKSLQLV-MEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQHY 1019 G + + S++ + +EY G L D + +G+ Q + Q+ G+ YLH + Sbjct 84 FG---KRSQGSVEYIFLEYAAGGELFDRI-EPDVGMPQHEAQRYFTQLLSGLNYLHQRGI 139 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N+LLD VKI DFG+A +G E + G P + APE L++ Sbjct 140 AHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLP--YVAPEVLQKAYH 197 Query 1079 YYASDVWSFGVTLYELL 1095 +D+WS GV L +L Sbjct 198 AQPADLWSCGVILVTML 214 Score = 36.6 bits (83), Expect = 1.6, Method: Compositional matrix adjust. Identities = 47/200 (24%), Positives = 81/200 (41%), Gaps = 24/200 (12%) Query 624 EDPLVPGRDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 E L+ R G+ V +K++D H D A + + + + H+ G +G Sbjct 35 EVKLLINRQTGEA--VAMKMVDLKKHPDAANSVRKEVCIQKMLQDKHILRFFGKRSQGSV 92 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 + EY G L + + G +P QL S L+YL + + H ++ N+LL Sbjct 93 EYIFLEYAAGGELFDRIEPDVG-MPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENLLL 151 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSR--------EERVERIPWLAPECLPGGANSLSTA 794 +K+SD G+ + R ++R +P++APE L + + Sbjct 152 DE-------HDNVKISD--FGMATMFRCKGKERLLDKRCGTLPYVAPEVLQKAYH--AQP 200 Query 795 MDKWGFGATLLEICFDGEAP 814 D W G L+ + GE P Sbjct 201 ADLWSCGVILVTM-LAGELP 219 >sp|Q8INB9|AKT1_DROME RAC serine/threonine-protein kinase OS=Drosophila melanogaster OX=7227 GN=Akt PE=1 SV=3 Length=611 Score = 83.6 bits (205), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 64/199 (32%), Positives = 95/199 (48%), Gaps = 12/199 (6%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHE 957 ++ LG+G FGKV L C + T ++ A+K LK + Q + E +L++ H Sbjct 269 LKVLGKGTFGKVIL-CRE---KATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHP 324 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA-QLLLFAQQICEGMAYLHA 1016 +I K Q L VM+YV G L +L I + + +I + YLH+ Sbjct 325 FLISLKYSF--QTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHS 382 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 Q I+RDL N+LLD D +K+ DFGL K E Y R + + APE L + Sbjct 383 QGIIYRDLKLENLLLDKDGHIKVADFGLCK---EDITYGRTTKTFCGTPEYLAPEVLDDN 439 Query 1077 KFYYASDVWSFGVTLYELL 1095 + A D W GV +YE++ Sbjct 440 DYGQAVDWWGTGVVMYEMI 458 Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust. Identities = 39/139 (28%), Positives = 62/139 (45%), Gaps = 17/139 (12%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 V +YV G L L ER + A+ + SAL YL ++ +++ ++ N+LL + Sbjct 341 FVMQYVNGGELFWHLSHERIFTEDRTRFYGAE-IISALGYLHSQGIIYRDLKLENLLLDK 399 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGF 800 G IK++D G+ ++ + +LAPE L N A+D WG Sbjct 400 DG-------HIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDD--NDYGQAVDWWGT 450 Query 801 GATLLE-ICFDGEAPLQSR 818 G + E IC G P +R Sbjct 451 GVVMYEMIC--GRLPFYNR 467 >sp|Q621J7|ZYG1_CAEBR Probable serine/threonine-protein kinase zyg-1 OS=Caenorhabditis briggsae OX=6238 GN=zyg-1 PE=3 SV=1 Length=709 Score = 83.6 bits (205), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 67/217 (31%), Positives = 109/217 (50%), Gaps = 26/217 (12%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 + ++ +G+G FG V Y N GE VA+K + + Q R K+EI ++ L H Sbjct 13 FQNLQQIGQGGFGVV--YSAQREN---GEKVAIKKI-GNAASQTR--IKEEIKTMKLLRH 64 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLH 1015 +I+++ + GE LVME GSL DY+ + + + + +Q+ + Y+H Sbjct 65 RNIVQFYETFFENGE--TYLVMELCEGGSLMDYVKQKGPLDDSTAVHILRQLIAAVKYIH 122 Query 1016 AQHYIHRDLAARNVLLDNDR----LVKIGDFGLAKAVPE-GHEYYRVREDGDSPVFWYAP 1070 ++ +HRDL+A NV + + VK+GDFGLA + + G V G + AP Sbjct 123 DENILHRDLSAGNVFIKDATKSTITVKLGDFGLATNLGQHGTACTIVGTPG-----FIAP 177 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + + + A+DV+S G LY +LT +PPTK Sbjct 178 QVFGQ-NYDQAADVYSLGAVLYTMLTK----HTPPTK 209 >sp|Q9LP51|CIPKI_ARATH CBL-interacting serine/threonine-protein kinase 18 OS=Arabidopsis thaliana OX=3702 GN=CIPK18 PE=1 SV=1 Length=520 Score = 83.2 bits (204), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 77/234 (33%), Positives = 114/234 (49%), Gaps = 33/234 (14%) Query 879 TVNPDSPAS-----DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933 ++P SP S + + K L K+ LG G F KV Y N +G+ VA+K + Sbjct 53 NISPQSPRSPRSPRNNILMGKYELGKL--LGHGTFAKV----YLAQNIKSGDKVAIKVI- 105 Query 934 ADCGPQHRSGW----KQEIDILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRD 988 D +SG K+EI ILR + H +I+ E KS + VMEYV G L + Sbjct 106 -DKEKIMKSGLVAHIKREISILRRVRHPYIVH---LFEVMATKSKIYFVMEYVGGGELFN 161 Query 989 YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + + + + QQ+ +++ H + HRDL N+LLDN +K+ DFGL+ AV Sbjct 162 TVAKGRLPEETARRYFQQLISSVSFCHGRGVYHRDLKPENLLLDNKGNLKVSDFGLS-AV 220 Query 1049 PEGHEYYRVREDGDSPVF-----WYAPECLKEYKFYYA-SDVWSFGVTLYELLT 1096 E ++R+DG F + APE L + A +DVWS GV L+ L+ Sbjct 221 AE-----QLRQDGLCHTFCGTPAYIAPEVLTRKGYDAAKADVWSCGVILFVLMA 269 Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust. Identities = 53/240 (22%), Positives = 97/240 (40%), Gaps = 25/240 (10%) Query 638 RVVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 +V +KV+D + S++ +V H ++ + V + V EYV G Sbjct 99 KVAIKVIDKEKIMKSGLVAHIKREISILRRVRHPYIVHLFEVMATKSKIYFVMEYVGGGE 158 Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 L + +G +P QQL S++S+ + + H ++ N+LL G Sbjct 159 L--FNTVAKGRLPEETARRYFQQLISSVSFCHGRGVYHRDLKPENLLLDNKG-------N 209 Query 755 IKLSDPGVGLGALSREERVERI--------PWLAPECLPGGANSLSTAMDKWGFGATLLE 806 +K+SD GL A++ + R + + ++APE L + A D W G L Sbjct 210 LKVSD--FGLSAVAEQLRQDGLCHTFCGTPAYIAPEVLTRKGYDAAKA-DVWSCGVILF- 265 Query 807 ICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + G P ++ + Y+ + R P L L ++ L P R + I+++ Sbjct 266 VLMAGHIPFYDKNIMVMYKKIYKGEFRCPRWFSSDLVRLLTRLLDTNPDTRITIPEIMKN 325 >sp|Q8W1D5|CIPKP_ARATH CBL-interacting serine/threonine-protein kinase 25 OS=Arabidopsis thaliana OX=3702 GN=CIPK25 PE=2 SV=1 Length=488 Score = 82.8 bits (203), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 66/207 (32%), Positives = 105/207 (51%), Gaps = 26/207 (13%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYH 956 R LG+G FGKV Y TGE VA+K + D R G K+EI I+R + H Sbjct 47 RLLGKGTFGKV----YYGKEITTGESVAIKIINKD--QVKREGMMEQIKREISIMRLVRH 100 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016 +I++ K + + + +MEYV G L + + + + QQ+ + + H+ Sbjct 101 PNIVELKEVMATKTK--IFFIMEYVKGGELFSKIVKGKLKEDSARKYFQQLISAVDFCHS 158 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG------DSPVFWYAP 1070 + HRDL N+L+D + +K+ DFGL+ A+PE ++ +DG +P + AP Sbjct 159 RGVSHRDLKPENLLVDENGDLKVSDFGLS-ALPE-----QILQDGLLHTQCGTPAY-VAP 211 Query 1071 ECLKEYKFYYAS-DVWSFGVTLYELLT 1096 E L++ + A D+WS G+ LY LL Sbjct 212 EVLRKKGYDGAKGDIWSCGIILYVLLA 238 Score = 38.1 bits (87), Expect = 0.47, Method: Compositional matrix adjust. Identities = 48/214 (22%), Positives = 88/214 (41%), Gaps = 22/214 (10%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M V H ++ + V + + EYV+ G L + + +G + QQL Sbjct 93 SIMRLVRHPNIVELKEVMATKTKIFFIMEYVKGGEL--FSKIVKGKLKEDSARKYFQQLI 150 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776 SA+ + ++ + H ++ N+L+ G +K+SD GL AL + + + Sbjct 151 SAVDFCHSRGVSHRDLKPENLLVDENGD-------LKVSD--FGLSALPEQILQDGLLHT 201 Query 777 -----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQ 830 ++APE L + D W G +L + G P Q + + ++ + Sbjct 202 QCGTPAYVAPEVLRKKGYDGAKG-DIWSCG-IILYVLLAGFLPFQDENLMKMYRKIFKSE 259 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 P P+ L S+ L +P +R S I+R Sbjct 260 FEYPPWFSPESKRLISKLLVVDPNKRISIPAIMR 293 >sp|Q8BPM2|M4K5_MOUSE Mitogen-activated protein kinase kinase kinase kinase 5 OS=Mus musculus OX=10090 GN=Map4k5 PE=1 SV=2 Length=847 Score = 84.0 bits (206), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 68/224 (30%), Positives = 105/224 (47%), Gaps = 25/224 (11%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 AD+L NP H L ++ +G G +G V Y N TGE+ AVK +K Sbjct 9 ADILRRNPQ---------HDYEL--VQRVGSGTYGDV----YKARNVHTGELAAVKIIKL 53 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRH 993 + G S +QEI +++ H +I+ Y G + L + MEY GSL+D Y Sbjct 54 EPGDDF-SLIQQEIFMVKECKHCNIVAYFGSY--LSREKLWICMEYCGGGSLQDIYHVTG 110 Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + Q+ ++ +G+AYLH + +HRD+ N+LL + VK+ DFG+A + Sbjct 111 PLSEMQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITAT-- 168 Query 1054 YYRVREDGDSPVFWYAPECL---KEYKFYYASDVWSFGVTLYEL 1094 R+ +W APE K + D+W+ G+T EL Sbjct 169 -IAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIEL 211 Score = 40.0 bits (92), Expect = 0.16, Method: Compositional matrix adjust. Identities = 49/190 (26%), Positives = 75/190 (39%), Gaps = 26/190 (14%) Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSRE 770 V ++ L+YL K +H ++ G NILL G +KL+D GV +++ Sbjct 120 VCRETLQGLAYLHTKGKMHRDIKGANILLTDHG-------DVKLADFGVAAKITATIAKR 172 Query 771 ERVERIP-WLAPECLP----GGANSLSTAMDKWGFGATLLEI------CFDGEAPLQSRS 819 + P W+APE GG N L D W G T +E+ FD P+++ Sbjct 173 KSFIGTPYWMAPEVAAVEKNGGYNQLC---DIWAVGITAIELGELQPPMFDLH-PMRALF 228 Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 K +F + + LT P +RP+ +L QP L+ L Sbjct 229 LMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVGQP-GLSRALA 287 Query 880 VNPDSPASDP 889 V S+P Sbjct 288 VELLDKVSNP 297 >sp|Q9M342|WAKLP_ARATH Wall-associated receptor kinase-like 15 OS=Arabidopsis thaliana OX=3702 GN=WAKL15 PE=2 SV=2 Length=639 Score = 83.6 bits (205), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 79/258 (31%), Positives = 118/258 (46%), Gaps = 43/258 (17%) Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917 S R + R+L + L + T A+D F K L LG G FG+V Sbjct 322 SVRKLHRNLLSINSTGLDRIFTGKEIVKATDN--FAKSNL-----LGFGGFGEVF----- 369 Query 918 PTNDGTGEMVAVKALKADCGPQHRSGWK--QEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 N G VAVK K +S ++ E+ IL + H++++K GCC + + Sbjct 370 KGNLDDGTTVAVKRAKLG---NEKSIYQIVNEVQILCQVSHKNLVKLLGCCIEL--EMPV 424 Query 976 LVMEYVPLGSL--------------RDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH--- 1018 LV E+VP G+L D+LP L + L+ A Q +G+ YLH+ Sbjct 425 LVYEFVPNGTLFEHIYGGGGGGGGLYDHLP-----LRRRLMIAHQTAQGLDYLHSSSSPP 479 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRD+ + N+LLD + VK+ DFGL++ + G + + PE ++ Sbjct 480 IYHRDVKSSNILLDENLDVKVADFGLSRLGVSDVSHVTTCAQG--TLGYLDPEYYLNFQL 537 Query 1079 YYASDVWSFGVTLYELLT 1096 SDV+SFGV L+ELLT Sbjct 538 TDKSDVYSFGVVLFELLT 555 Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust. Identities = 55/254 (22%), Positives = 102/254 (40%), Gaps = 36/254 (14%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 AS R L+ + LS + I + + T L G G+ +G +DD + Sbjct 321 ASVRKLHRNLLSINSTGLDRIFTGKEIVKATDNFAKSNLLGFGGFGEVFKGNLDDGTTVA 380 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 R + + + ++++ ++ QVSH +L + G C+ ++V E Sbjct 381 VKRAKLGNEKSIYQIVNE------------VQILCQVSHKNLVKLLGCCIELEMPVLVYE 428 Query 689 YVEHGPLDVWLRRER-------GHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGR 738 +V +G L + H+P+ ++++A Q A L YL + + + H +V Sbjct 429 FVPNGTLFEHIYGGGGGGGGLYDHLPLRRRLMIAHQTAQGLDYLHSSSSPPIYHRDVKSS 488 Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLST 793 NILL + +K++D G+ +S V + +L PE L+ Sbjct 489 NILLDE-------NLDVKVADFGLSRLGVSDVSHVTTCAQGTLGYLDPEYYLNF--QLTD 539 Query 794 AMDKWGFGATLLEI 807 D + FG L E+ Sbjct 540 KSDVYSFGVVLFEL 553 >sp|Q9HFF4|PPK1_SCHPO Serine/threonine-protein kinase ppk1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ppk1 PE=1 SV=2 Length=1023 Score = 84.0 bits (206), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 73/220 (33%), Positives = 103/220 (47%), Gaps = 33/220 (15%) Query 901 RDLGEGHFGKVSLYCYDPTNDGT----GEMVAVK---ALKADCGPQHRSGWKQEIDILRT 953 R +G G FGKV L P + T V +K + K +C S +E+ IL+ Sbjct 496 RTIGTGEFGKVKLGWPLPKANSTIHRSTPQVVIKIVLSTKQNC---QTSRLMREVAILKG 552 Query 954 L--YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICEG 1010 L H HI+KY + + +V++YV G L DY L R + + Q+ G Sbjct 553 LGNNHPHIVKYLDFVKTKHH--FGIVLDYVNGGELFDYILARRRLEDSVACRLFAQLISG 610 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH-----EYYRVREDGD--- 1062 +AYLH++ +HRDL N+LLD +R + I DFG A GH E+ E D Sbjct 611 VAYLHSRGVVHRDLKLENILLDTNRNIVIADFGFATTF--GHFNTLSEHSLPTEKPDLFS 668 Query 1063 ----SPVFWYAPECLKEYKFYYA---SDVWSFGVTLYELL 1095 SP + APE + YA +D+WS GV LY +L Sbjct 669 TSCGSPC-YAAPELVNCKSGMYAGTQADIWSCGVILYAML 707 >sp|Q01919|KIN4_YEAST Serine/threonine-protein kinase KIN4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=KIN4 PE=1 SV=1 Length=800 Score = 83.6 bits (205), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 67/201 (33%), Positives = 99/201 (49%), Gaps = 14/201 (7%) Query 903 LGEGHFGKVSL-YCYDPTNDGTGEMVAVKALKADC---GPQHRSGWKQEIDILRTLYHEH 958 LGEG FGKV L + +++ + VA+K ++ D +EI+ L+ L H + Sbjct 52 LGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPN 111 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHA 1016 II + Q K + +V+E+V G Y+ R + LFAQ I G+ Y+H Sbjct 112 IIYLEEVL--QNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLIS-GVNYMHY 168 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + +HRDL N+LLD + I DFG E +E ++ SP + APE + Sbjct 169 KGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNEL--MKTSCGSPCYA-APELVVST 225 Query 1077 KFYYA--SDVWSFGVTLYELL 1095 K Y A +DVWS GV LY +L Sbjct 226 KAYEARKADVWSCGVILYAML 246 >sp|Q7RZD3|STE20_NEUCR Serine/threonine-protein kinase ste20 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=stk-4 PE=3 SV=1 Length=954 Score = 84.0 bits (206), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 55/208 (26%), Positives = 101/208 (49%), Gaps = 14/208 (7%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP ++ + K +G+G G V Y G+ +VA+K + + P+ + E Sbjct 669 DPREIYRGFTK----IGQGASGGV----YTGHERGSNRLVAIKQMNLEQQPK-KDLIINE 719 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +++ H +I+ + GE L +VMEY+ GSL D + + + Q+ ++ Sbjct 720 ILVMKESSHPNIVNFIDSYLCAGE--LWVVMEYMEGGSLTDVVTFNIMTEGQIASVCRET 777 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 G+ +LH++ IHRD+ + N+LL + +K+ DFG + E + R G +W Sbjct 778 LRGLQHLHSKGVIHRDIKSDNILLSMEGNIKLTDFGFCATINEA-QSKRTTMVGTP--YW 834 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095 APE + ++ D+WS G+ E++ Sbjct 835 MAPEVVTRKEYGRKVDIWSLGIMAIEMI 862 Score = 43.1 bits (100), Expect = 0.017, Method: Compositional matrix adjust. Identities = 52/206 (25%), Positives = 85/206 (41%), Gaps = 38/206 (18%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA-FVHGVCVRGPENIMVTE 688 G +RG V +K ++ +M + SH ++ F+ G E +V E Sbjct 691 GHERGSNRLVAIKQMNLEQQPKKDLIINEILVMKESSHPNIVNFIDSYLCAG-ELWVVME 749 Query 689 YVEHGPL-DVWLRRERGHVPMAWKMVVAQQLAS-------ALSYLENKNLVHGNVCGRNI 740 Y+E G L DV + + ++ Q+AS L +L +K ++H ++ NI Sbjct 750 YMEGGSLTDV----------VTFNIMTEGQIASVCRETLRGLQHLHSKGVIHRDIKSDNI 799 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTA 794 LL+ G IKL+D G A E + +R W+APE + Sbjct 800 LLSMEG-------NIKLTD--FGFCATINEAQSKRTTMVGTPYWMAPEVV--TRKEYGRK 848 Query 795 MDKWGFGATLLEICFDGEAPLQSRSP 820 +D W G +E+ +GE P + SP Sbjct 849 VDIWSLGIMAIEM-IEGEPPYLTESP 873 >sp|O04533|LRK52_ARATH Putative L-type lectin-domain containing receptor kinase V.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK52 PE=3 SV=1 Length=656 Score = 83.2 bits (204), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 66/202 (33%), Positives = 99/202 (49%), Gaps = 23/202 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---EIDILRTLYHEHI 959 LG+G FGKV + + +AVK + D R G ++ EI + L H + Sbjct 340 LGKGGFGKV----FKGILPLSSIPIAVKKISHDS----RQGMREFLAEIATIGRLRHPDL 391 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH- 1015 ++ G C +GE L LV +++P GSL +L P + +Q + + G+ YLH Sbjct 392 VRLLGYCRRKGE--LYLVYDFMPKGSLDKFLYNQPNQILDWSQRFNIIKDVASGLCYLHQ 449 Query 1016 --AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072 Q IHRD+ N+LLD + K+GDFGLAK G + G F Y +PE Sbjct 450 QWVQVIIHRDIKPANILLDENMNAKLGDFGLAKLCDHGIDSQTSNVAG---TFGYISPEL 506 Query 1073 LKEYKFYYASDVWSFGVTLYEL 1094 + K +SDV++FGV + E+ Sbjct 507 SRTGKSSTSSDVFAFGVFMLEI 528 >sp|Q2TBL8|CDK10_BOVIN Cyclin-dependent kinase 10 OS=Bos taurus OX=9913 GN=CDK10 PE=2 SV=1 Length=361 Score = 81.3 bits (199), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 69/214 (32%), Positives = 101/214 (47%), Gaps = 26/214 (12%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDI 950 + +K+ +GEG +G V Y + T E+VA+K ++ D + + G +EI + Sbjct 35 KEFEKLNRIGEGTYGIV----YRARDTHTDEIVALKKVRMD---KEKDGVPISSLREITL 87 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQIC 1008 L L H +I++ K +S+ LVM Y L SL + +P AQ+ Q+ Sbjct 88 LLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPT-PFSEAQVKCIVLQVL 146 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP---V 1065 G+ YLH IHRDL N+L+ + VK DFGLA+A Y + +P Sbjct 147 RGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARA-------YGIPVKPMTPKVVT 199 Query 1066 FWY-APECLKEYKFYYAS-DVWSFGVTLYELLTH 1097 WY APE L S D+W+ G L ELL H Sbjct 200 LWYRAPELLLGTTTQTTSIDMWAVGCILAELLAH 233 >sp|Q2VWQ3|STE20_TALMA Serine/threonine-protein kinase pakA OS=Talaromyces marneffei OX=37727 GN=pakA PE=3 SV=1 Length=642 Score = 83.2 bits (204), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 57/208 (27%), Positives = 103/208 (50%), Gaps = 14/208 (7%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DPT K+Y + +G+G G V Y+ TN T + VA+K + D P+ + E Sbjct 356 DPT---KKYYN-LNKIGQGASGGV-FTAYE-TN--TNKCVAIKQMNLDLQPK-KDLIINE 406 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +++ H++I+ + + L +VMEY+ GSL D + + + Q+ ++ Sbjct 407 ILVMKDSKHKNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMSEGQIAAVCRET 464 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 G+ +LH++ IHRD+ + N+LL D +K+ DFG + ++ R +W Sbjct 465 LSGLQHLHSKGVIHRDIKSDNILLSMDGEIKLTDFGFCAQI---NDSQNKRNTMVGTPYW 521 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095 APE + ++ D+WS G+ E++ Sbjct 522 MAPEVVTRKEYGRKVDIWSLGIMAIEMI 549 Score = 39.3 bits (90), Expect = 0.24, Method: Compositional matrix adjust. Identities = 43/165 (26%), Positives = 69/165 (42%), Gaps = 18/165 (11%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719 +M H ++ + G + +V EY+E G L DV +A V ++ Sbjct 409 VMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVVTFNIMSEGQIA---AVCRETL 465 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERVER 775 S L +L +K ++H ++ NILL+ G IKL+D G + R V Sbjct 466 SGLQHLHSKGVIHRDIKSDNILLSMDGE-------IKLTDFGFCAQINDSQNKRNTMVGT 518 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 W+APE + +D W G +E+ +GE P + SP Sbjct 519 PYWMAPEVV--TRKEYGRKVDIWSLGIMAIEM-IEGEPPYLTESP 560 >sp|Q8GYA4|CRK10_ARATH Cysteine-rich receptor-like protein kinase 10 OS=Arabidopsis thaliana OX=3702 GN=CRK10 PE=1 SV=3 Length=669 Score = 83.2 bits (204), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 84/284 (30%), Positives = 132/284 (46%), Gaps = 31/284 (11%) Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G FG+V Y T +DGT VAVK L G Q +K E+ ++ L H ++++ Sbjct 354 IGQGGFGEV----YKGTLSDGT--EVAVKRLSKSSG-QGEVEFKNEVVLVAKLQHRNLVR 406 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 G C D E+ L V EYVP SL +L + + + + G+ YLH Sbjct 407 LLGFCLDGEERVL--VYEYVPNKSLDYFLFDPAKKGQLDWTRRYKIIGGVARGILYLHQD 464 Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF----WYAP 1070 IHRDL A N+LLD D KI DFG+A+ E+ S + + +P Sbjct 465 SRLTIIHRDLKASNILLDADMNPKIADFGMARIFGLDQT-----EENTSRIVGTYGYMSP 519 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL-ELIGIAQGQMTVLRLTELLE 1129 E ++ SDV+SFGV + E+++ +S T +L+ A G + R EL++ Sbjct 520 EYAMHGQYSMKSDVYSFGVLVLEIISGKKNSSFYQTDGAHDLVSYAWGLWSNGRPLELVD 579 Query 1130 RG--ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 E R + C H+ C + + + RPT ++ +L + Sbjct 580 PAIVENCQRNEVVRC--VHIGLLCVQEDPAERPTLSTIVLMLTS 621 Score = 51.2 bits (121), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 64/270 (24%), Positives = 109/270 (40%), Gaps = 63/270 (23%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K L S + F L++++ H +L + G C+ G E ++V EYV + LD + Sbjct 373 VAVKRLSKSSGQGEVEFKNEVVLVAKLQHRNLVRLLGFCLDGEERVLVYEYVPNKSLDYF 432 Query 699 LRR--ERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSP 753 L ++G + + + +A + YL + ++H ++ NIL L +P Sbjct 433 LFDPAKKGQLDWTRRYKIIGGVARGILYLHQDSRLTIIHRDLKASNIL-----LDADMNP 487 Query 754 FIKLSDPGVG--LGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 K++D G+ G EE RI +++PE G S+ + D + FG +LEI Sbjct 488 --KIADFGMARIFGLDQTEENTSRIVGTYGYMSPEYAMHGQYSMKS--DVYSFGVLVLEI 543 Query 808 CFDGEAPLQSRSPSEKEHFYQ------------------RQHRLPEPS------------ 837 S + FYQ R L +P+ Sbjct 544 I----------SGKKNSSFYQTDGAHDLVSYAWGLWSNGRPLELVDPAIVENCQRNEVVR 593 Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 C + L C+ +P +RP+ TI+ LT Sbjct 594 CVHIGLL---CVQEDPAERPTLSTIVLMLT 620 >sp|Q15831|STK11_HUMAN Serine/threonine-protein kinase STK11 OS=Homo sapiens OX=9606 GN=STK11 PE=1 SV=1 Length=433 Score = 82.0 bits (201), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 59/198 (30%), Positives = 95/198 (48%), Gaps = 6/198 (3%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG +GKV D + +K K P + K+EI +LR L H+++I+ Sbjct 55 LGEGSYGKVK-EVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQL 113 Query 963 KGCCEDQGEKSLQLVMEYVPLG--SLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 ++ ++ + +VMEY G + D +P + Q + Q+ +G+ YLH+Q + Sbjct 114 VDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIV 173 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 H+D+ N+LL +KI D G+A+A+ R SP F PE + Sbjct 174 HKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQ-PPEIANGLDTFS 232 Query 1080 -YASDVWSFGVTLYELLT 1096 + D+WS GVTLY + T Sbjct 233 GFKVDIWSAGVTLYNITT 250 Score = 43.5 bits (101), Expect = 0.009, Method: Compositional matrix adjust. Identities = 48/188 (26%), Positives = 73/188 (39%), Gaps = 21/188 (11%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL-- 742 MV EY G ++ P+ QL L YL ++ +VH ++ N+LL Sbjct 127 MVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTT 186 Query 743 ------ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLST-AM 795 + LG+AE PF G+ P P + G ++ S + Sbjct 187 GGTLKISDLGVAEALHPFAADDTCRTSQGS----------PAFQPPEIANGLDTFSGFKV 236 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854 D W G TL I G P + + + E+ + + +P P L+ L L YEP Sbjct 237 DIWSAGVTLYNIT-TGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPA 295 Query 855 QRPSFRTI 862 +R S R I Sbjct 296 KRFSIRQI 303 >sp|O88866|HUNK_MOUSE Hormonally up-regulated neu tumor-associated kinase OS=Mus musculus OX=10090 GN=Hunk PE=2 SV=1 Length=714 Score = 83.6 bits (205), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 69/213 (32%), Positives = 98/213 (46%), Gaps = 18/213 (8%) Query 893 HKR---YLKKIRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKAL---KADCGPQHRSGW 944 HKR YL R LGEG F KV L+ TGE VA+K + +A Sbjct 55 HKRVGNYLIGSRKLGEGSFAKVREGLHVL------TGEKVAIKVIDKKRAKKDTYVTKNL 108 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLF 1003 ++E I + + H +I + E E S LVME P G+L + + + A+ + Sbjct 109 RREGQIQQMIRHPNITQLLDILET--ENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRY 166 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 +Q+ + +LH +HRDL N+LLD D +K+ DFGL+ S Sbjct 167 IRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGS 226 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 P + APE L K+ DVWS GV +Y +LT Sbjct 227 PAYA-APELLARKKYGPKIDVWSIGVNMYAMLT 258 >sp|Q3UMM4|CDK10_MOUSE Cyclin-dependent kinase 10 OS=Mus musculus OX=10090 GN=Cdk10 PE=1 SV=1 Length=360 Score = 81.3 bits (199), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 70/214 (33%), Positives = 101/214 (47%), Gaps = 26/214 (12%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDI 950 + +K+ +GEG +G V Y + T E+VA+K ++ D + + G +EI + Sbjct 37 KEFEKLNRIGEGTYGIV----YRARDTQTDEIVALKKVRMD---KEKDGIPISSLREITL 89 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQIC 1008 L L H +I++ K +S+ LVM Y L SL + +P AQ+ Q+ Sbjct 90 LLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPT-PFSEAQVKCIMLQVL 148 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP---V 1065 G+ YLH IHRDL N+L+ + VK DFGLA+A Y V +P Sbjct 149 RGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARA-------YGVPVKPMTPKVVT 201 Query 1066 FWY-APECLKEYKFYYAS-DVWSFGVTLYELLTH 1097 WY APE L S D+W+ G L ELL H Sbjct 202 LWYRAPELLLGTTTQTTSIDMWAVGCILAELLAH 235 >sp|P34722|KPC1_CAEEL Protein kinase C-like 1 OS=Caenorhabditis elegans OX=6239 GN=tpa-1 PE=1 SV=2 Length=704 Score = 83.2 bits (204), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 71/220 (32%), Positives = 99/220 (45%), Gaps = 38/220 (17%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH- 958 ++ LG+G FGKV L G E A+K LK D E D Y E Sbjct 378 LKVLGKGSFGKVMLV----ELKGKNEFYAMKCLKKDV--------ILEDDDTECTYIERR 425 Query 959 -IIKYKGC-------CEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICE 1009 +I C C Q + L VMEY+ G L ++ + A+ +A +I Sbjct 426 VLILASQCPFLCQLFCSFQTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVV 485 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF--- 1066 + +LH + I+RDL NVLLD D +K+ DFG+AK RE+G + F Sbjct 486 ALQFLHTNNIIYRDLKLDNVLLDCDGHIKLADFGMAKTEMN-------RENGMASTFCGT 538 Query 1067 --WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 + +PE +K + A D WSFGV +YE+L QSP Sbjct 539 PDYISPEIIKGQLYNEAVDFWSFGVLMYEMLV----GQSP 574 >sp|Q9Y4K4|M4K5_HUMAN Mitogen-activated protein kinase kinase kinase kinase 5 OS=Homo sapiens OX=9606 GN=MAP4K5 PE=1 SV=3 Length=846 Score = 83.6 bits (205), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 66/224 (29%), Positives = 106/224 (47%), Gaps = 25/224 (11%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 AD+L NP ++ + ++ +G G +G V Y N TGE+ AVK +K Sbjct 9 ADILRRNP-----------QQDYELVQRVGSGTYGDV----YKARNVHTGELAAVKIIKL 53 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRH 993 + G S +QEI +++ H +I+ Y G + L + MEY GSL+D Y Sbjct 54 EPGDDF-SLIQQEIFMVKECKHCNIVAYFGSY--LSREKLWICMEYCGGGSLQDIYHVTG 110 Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + Q+ ++ +G+AYLH + +HRD+ N+LL + VK+ DFG+A + Sbjct 111 PLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITAT-- 168 Query 1054 YYRVREDGDSPVFWYAPECL---KEYKFYYASDVWSFGVTLYEL 1094 R+ +W APE K + D+W+ G+T EL Sbjct 169 -IAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIEL 211 Score = 40.8 bits (94), Expect = 0.088, Method: Compositional matrix adjust. Identities = 51/194 (26%), Positives = 77/194 (40%), Gaps = 33/194 (17%) Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSRE 770 V ++ L+YL K +H ++ G NILL G +KL+D GV +++ Sbjct 120 VCRETLQGLAYLHTKGKMHRDIKGANILLTDHG-------DVKLADFGVAAKITATIAKR 172 Query 771 ERVERIP-WLAPECLP----GGANSLSTAMDKWGFGATLLEI------CFDGEAPLQSRS 819 + P W+APE GG N L D W G T +E+ FD P+++ Sbjct 173 KSFIGTPYWMAPEVAAVEKNGGYNQLC---DIWAVGITAIELGELQPPMFDLH-PMRALF 228 Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 K +F + + LT P +RP+ +L QP L+ L Sbjct 229 LMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQP-GLSRALA 287 Query 880 V-------NPDSPA 886 V NPD+ A Sbjct 288 VELLDKVNNPDNHA 301 >sp|Q9U2Q9|GSK3_CAEEL Glycogen synthase kinase-3 OS=Caenorhabditis elegans OX=6239 GN=gsk-3 PE=1 SV=1 Length=362 Score = 81.3 bits (199), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 69/209 (33%), Positives = 102/209 (49%), Gaps = 35/209 (17%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V L TN EMVA+K + D ++R E+ I+R L H +I+K Sbjct 42 IGNGSFGVVFLAKLSTTN----EMVAIKKVLQDKRFKNR-----ELQIMRKLNHPNIVKL 92 Query 963 KGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRH------SIGLAQLLLFAQQICEGMA 1012 K GEK L L++EYVP R + RH I + + L+ Q+ +A Sbjct 93 KYFFYSSGEKKDELYLNLILEYVPETVYR--VARHYSKQRQQIPMIYVKLYMYQLLRSLA 150 Query 1013 YLHAQHYIHRDLAARNVLLDNDR-LVKIGDFGLAKAVPEGHEYYRVREDGDSPV----FW 1067 Y+H+ HRD+ +N+L+D + ++K+ DFG AK Y VR + + ++ Sbjct 151 YIHSIGICHRDIKPQNLLIDPESGVLKLCDFGSAK--------YLVRNEPNVSYICSRYY 202 Query 1068 YAPECLKEYKFYYAS-DVWSFGVTLYELL 1095 APE + Y S DVWS G + ELL Sbjct 203 RAPELIFGATNYTNSIDVWSAGTVMAELL 231 Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust. Identities = 66/325 (20%), Positives = 131/325 (40%), Gaps = 70/325 (22%) Query 573 TLNLSQLSFHRVDQK-EITQLSH--LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 T+ ++ ++ VDQ+ EI+ +G G+ V+ +L + + D+ Sbjct 17 TMVVASVATDGVDQQVEISYYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKVLQDK----- 71 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 R + +EL+++ K+ P+ + FY + ++ ++ EY Sbjct 72 -RFKNRELQIMRKLNHPNIVKLKYFFYSSGEKKDELYLN----------------LILEY 114 Query 690 VEHGPLDVW--LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 V V ++R +PM + + QL +L+Y+ + + H ++ +N+L+ Sbjct 115 VPETVYRVARHYSKQRQQIPMIYVKLYMYQLLRSLAYIHSIGICHRDIKPQNLLI----- 169 Query 748 AEGTSPFIKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGFGATL 804 + S +KL D G + E V I + APE + G N + ++D W G + Sbjct 170 -DPESGVLKLCDFGSAKYLVRNEPNVSYICSRYYRAPELIFGATN-YTNSIDVWSAGTVM 227 Query 805 LEI-----CFDGEA------------------PLQSRSPSEKE--------HFYQRQHRL 833 E+ F G++ +QS +P+ KE H + + R+ Sbjct 228 AELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIQSMNPNYKEFKFPQIKAHPWNKVFRV 287 Query 834 PEPSCPQLATLTSQCLTYEPTQRPS 858 P+ + L S+ + Y PT RP+ Sbjct 288 HTPA--EAIDLISKIIEYTPTSRPT 310 >sp|Q9W739|CDK1_RANDY Cyclin-dependent kinase 1 OS=Rana dybowskii OX=71582 GN=CDK1 PE=2 SV=1 Length=302 Score = 80.5 bits (197), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 70/236 (30%), Positives = 117/236 (50%), Gaps = 29/236 (12%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957 KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L H Sbjct 6 KIEKIGEGTYGVV----YKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query 958 HIIKYKGCCED--QGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLL--FAQQICEGM 1011 +I+ C D + L L+ E++ + L+ YL G L +L+ + QI +G+ Sbjct 62 NIV----CLLDVLMQDSRLYLIFEFLSM-DLKKYLDSIPSGQYLEAMLVKSYLYQILQGI 116 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWYA 1069 + HA+ +HRDL +N+L+D+ ++K+ DFGLA+A +P RV +++ A Sbjct 117 IFCHARRVLHRDLKPQNLLIDSKGVIKLADFGLARAFGIP-----VRVYTHEVVTLWYRA 171 Query 1070 PEC-LKEYKFYYASDVWSFGVTLYEL-----LTHCDSSQSPPTKFLELIGIAQGQM 1119 PE L ++ DVWS G E+ L H DS + EL G ++ Sbjct 172 PEVLLGSVRYSTPVDVWSIGTIFAEIASKKPLFHGDSEIDQLFRISELWGTPNNEV 227 >sp|P48562|CLA4_YEAST Serine/threonine-protein kinase CLA4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CLA4 PE=1 SV=1 Length=842 Score = 83.6 bits (205), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 53/180 (29%), Positives = 90/180 (50%), Gaps = 13/180 (7%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 G+ VA+K + P+ + EI +++ H++I+ + + + L +VME++ Sbjct 588 GDKVAIKQMVLSKQPR-KELIVNEILVMKDSRHKNIVNFLEAYL-RTDDDLWVVMEFMEG 645 Query 984 GSLRDYLPR-------HS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035 GSL D + HS + Q+ ++ C+G+ +LH +H IHRD+ + NVLLD Sbjct 646 GSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRA 705 Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 VKI DFG + + R +W APE +K+ ++ DVWS G+ E+L Sbjct 706 RVKITDFGFCARLTDKRSK---RATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEML 762 Score = 39.7 bits (91), Expect = 0.20, Method: Compositional matrix adjust. Identities = 31/143 (22%), Positives = 63/143 (44%), Gaps = 25/143 (17%) Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENKNLVHGNVCGRNILLA 743 +T+ +E+ P + + H P+ + + ++ L +L +K+++H ++ N+LL Sbjct 648 LTDIIENSPTN-----DNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLL- 701 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAMDK 797 T +K++D G A ++R +R W+APE + +D Sbjct 702 ------DTRARVKITD--FGFCARLTDKRSKRATMVGTPYWMAPEVV--KQREYDEKIDV 751 Query 798 WGFGATLLEICFDGEAPLQSRSP 820 W G +E+ +GE P + P Sbjct 752 WSLGIMTIEM-LEGEPPYLNEDP 773 >sp|Q9LXA5|LRK91_ARATH L-type lectin-domain containing receptor kinase IX.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK91 PE=1 SV=1 Length=651 Score = 83.2 bits (204), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 84/290 (29%), Positives = 134/290 (46%), Gaps = 40/290 (14%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LGEG FG V Y + MVA+K A Q + + E+ I+ +L H +++ Sbjct 339 RKLGEGGFGAV----YRGYLNSLDMMVAIKKF-AGGSKQGKREFVTEVKIISSLRHRNLV 393 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------------RHSIGLAQLLLFAQQIC 1008 + G C ++ E ++ E++P GSL +L + ++GLA LL+ + Sbjct 394 QLIGWCHEKDE--FLMIYEFMPNGSLDAHLFGKKPHLAWHVRCKITLGLASALLYLHEEW 451 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 E Q +HRD+ A NV+LD++ K+GDFGLA+ + HE + G + F Y Sbjct 452 E-------QCVVHRDIKASNVMLDSNFNAKLGDFGLARLMD--HE-LGPQTTGLAGTFGY 501 Query 1069 -APECLKEYKFYYASDVWSFGVTLYELLT---HCDSSQS---PPTKFLELIGIAQGQMTV 1121 APE + + SDV+SFGV E++T D Q P T +E + G+ V Sbjct 502 MAPEYISTGRASKESDVYSFGVVTLEIVTGRKSVDRRQGRVEPVTNLVEKMWDLYGKGEV 561 Query 1122 LR-LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + + E L G + +C V C + + RP+ + I +L Sbjct 562 ITAIDEKLRIGGFDEKQAECLMIVGLW---CAHPDVNTRPSIKQAIQVLN 608 Score = 42.4 bits (98), Expect = 0.029, Method: Compositional matrix adjust. Identities = 40/158 (25%), Positives = 69/158 (44%), Gaps = 9/158 (6%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F ++S + H +L + G C E +M+ E++ +G LD L ++ H+ + + Sbjct 377 FVTEVKIISSLRHRNLVQLIGWCHEKDEFLMIYEFMPNGSLDAHLFGKKPHLAWHVRCKI 436 Query 715 AQQLASALSYLE---NKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSRE 770 LASAL YL + +VH ++ N++L + G +L D +G Sbjct 437 TLGLASALLYLHEEWEQCVVHRDIKASNVMLDSNFNAKLGDFGLARLMDHELGPQTTG-- 494 Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 ++APE + G S + D + FG LEI Sbjct 495 -LAGTFGYMAPEYISTGRASKES--DVYSFGVVTLEIV 529 >sp|Q55FS2|STK4L_DICDI Serine/threonine-protein kinase 4 homolog B OS=Dictyostelium discoideum OX=44689 GN=krsB PE=3 SV=1 Length=1105 Score = 83.6 bits (205), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 55/197 (28%), Positives = 96/197 (49%), Gaps = 14/197 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I LG G FG V Y T TG +VAVK + + Q +EI+I++ +++ Sbjct 26 IECLGRGSFGSV----YKATYKKTGNIVAVKLVPINEDFQE---ILKEINIMKQCKSKYV 78 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 ++Y G +++ ++MEY GS+ D + + Q+ L +G+ YLH Sbjct 79 VQYYGNYFK--DETCWIIMEYCAFGSVSDMMNITNRVLNEEQIALVCYSTLKGLYYLHRN 136 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ N+L+ + K+ DFG++ + E R R F+ APE ++E Sbjct 137 SKIHRDIKPGNILVSEEGECKLADFGVSGQL---SERTRKRNTVIGTPFFLAPEVIQEVG 193 Query 1078 FYYASDVWSFGVTLYEL 1094 + +D+W+ G++ E+ Sbjct 194 YDNKADIWALGISAIEM 210 Score = 38.5 bits (88), Expect = 0.46, Method: Compositional matrix adjust. Identities = 53/244 (22%), Positives = 90/244 (37%), Gaps = 37/244 (15%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V L P + D E ++M Q ++ +G + ++ EY G + Sbjct 47 NIVAVKLVPINEDFQEILKE-INIMKQCKSKYVVQYYGNYFKDETCWIIMEYCAFGSVSD 105 Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + + +V L YL + +H ++ NIL++ G KL Sbjct 106 MMNITNRVLNEEQIALVCYSTLKGLYYLHRNSKIHRDIKPGNILVSEEGEC-------KL 158 Query 758 SDPGVGLGALSREERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEIC---- 808 +D GV G LS R +LAPE + D W G + +E+ Sbjct 159 ADFGVS-GQLSERTRKRNTVIGTPFFLAPEVIQEVG--YDNKADIWALGISAIEMAEFHP 215 Query 809 -FDGEAPLQ-------SRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 + P++ S SP+ KE P P+ + + CL E +QRPS + Sbjct 216 PYHDLHPMRVLFMIPTSTSPTLKE---------PHKWSPEFSDFIALCLAKEQSQRPSAK 266 Query 861 TILR 864 +L+ Sbjct 267 DLLK 270 >sp|Q8VCR8|MYLK2_MOUSE Myosin light chain kinase 2, skeletal/cardiac muscle OS=Mus musculus OX=10090 GN=Mylk2 PE=1 SV=2 Length=613 Score = 83.2 bits (204), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 61/198 (31%), Positives = 99/198 (50%), Gaps = 15/198 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V C T TG +A K +K P+ + EI+++ L H ++I+ Sbjct 308 LGGGKFGAV-CTC---TERATGLKLAAKVIKKQT-PKDKEMVLLEIEVMNQLNHRNLIQL 362 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020 E E + L MEY+ G L + + L ++ ++F +QIC+G+ ++H + Sbjct 363 YAAIETSHE--IILFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVL 420 Query 1021 HRDLAARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 H DL N+L N LVKI DFGLA+ + +++ + +P F +PE + + Sbjct 421 HLDLKPENILCVNTTGHLVKIIDFGLARRY---NPNEKLKVNFGTPEF-LSPEVVNYDQI 476 Query 1079 YYASDVWSFGVTLYELLT 1096 +D+WS GV Y LL+ Sbjct 477 SDKTDMWSLGVITYMLLS 494 Score = 38.5 bits (88), Expect = 0.43, Method: Compositional matrix adjust. Identities = 40/180 (22%), Positives = 75/180 (42%), Gaps = 24/180 (13%) Query 632 DRGQELRVVLKVLD---PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 +R L++ KV+ P ++ L E +M+Q++H +L ++ E I+ E Sbjct 321 ERATGLKLAAKVIKKQTPKDKEMVLLEIE---VMNQLNHRNLIQLYAAIETSHEIILFME 377 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 Y+E G L + E H+ MV +Q+ + ++ ++H ++ NIL Sbjct 378 YIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNT--- 434 Query 749 EGTSPFIKLSDPGVGLGALSREERVERIP-------WLAPECLPGGANSLSTAMDKWGFG 801 T +K+ D G R E++ +L+PE + + +S D W G Sbjct 435 --TGHLVKIID----FGLARRYNPNEKLKVNFGTPEFLSPEVV--NYDQISDKTDMWSLG 486 >sp|Q55GE6|ROCO7_DICDI Probable serine/threonine-protein kinase roco7 OS=Dictyostelium discoideum OX=44689 GN=roco7 PE=3 SV=1 Length=2615 Score = 84.0 bits (206), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 81/332 (24%), Positives = 148/332 (45%), Gaps = 58/332 (17%) Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926 T++ ++LA +T N + + P LK LG G + V ++ G Sbjct 1749 TKIDIYSLAFEVTFNSNKFSVIP----YETLKFGPQLGSGSYANVYRGIWN------GSE 1798 Query 927 VAVKALKADCGPQHRSG----WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982 VA+K L D G + + ++ E I L H + + G LV E + Sbjct 1799 VAIKVLNFDDGHANTTEKYREFRNEAHITGELRHANTVSLMGV----SLSPFCLVTELLQ 1854 Query 983 LGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHA--QHYIHRDLAARNVLL---DNDR 1035 G L ++ + +L A + +GM +LH+ +HRDL + N+LL D Sbjct 1855 YGDLAKFIRNTAETFSWGTVLKLAIDVAKGMNFLHSCKPMIVHRDLKSANILLGGSSMDN 1914 Query 1036 LV-KIGDFGLA-----KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 LV K+GDFGL+ K V +G + + R W APEC+ + ++ D++S+ + Sbjct 1915 LVAKVGDFGLSIKPIGKEV-KGRKVWNWR--------WLAPECMGDGQYTEKIDIYSYAI 1965 Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE----RGERLPRPDKCPCEVY 1145 L+E++T P ++++ L+ ++E +G R P++CP ++ Sbjct 1966 VLWEIITR----DLPFEEYVDQ----------LKWNSIIEDKIMKGLRPTIPNECPPDMK 2011 Query 1146 HLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 L+ +CW + RP+F +++ L T+ + + Sbjct 2012 QLITDCWSGDPKKRPSFNSILERLSTMQKTFN 2043 Score = 58.5 bits (140), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 57/252 (23%), Positives = 112/252 (44%), Gaps = 21/252 (8%) Query 633 RGQELRVVLKVLDPSHHDIALAFYE---TASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G E+ + + D H + + E A + ++ H + + GV + +VTE Sbjct 1795 NGSEVAIKVLNFDDGHANTTEKYREFRNEAHITGELRHANTVSLMGVSLS--PFCLVTEL 1852 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGL 747 +++G L ++R + +A +A +++L + +VH ++ NILL G Sbjct 1853 LQYGDLAKFIRNTAETFSWGTVLKLAIDVAKGMNFLHSCKPMIVHRDLKSANILL---GG 1909 Query 748 AEGTSPFIKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGFGATL 804 + + K+ D G+ + + +E + ++ WLAPEC+ G + +D + + L Sbjct 1910 SSMDNLVAKVGDFGLSIKPIGKEVKGRKVWNWRWLAPECM--GDGQYTEKIDIYSYAIVL 1967 Query 805 LEIC-----FDGEAP-LQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPS 858 EI F+ L+ S E + + +P P + L + C + +P +RPS Sbjct 1968 WEIITRDLPFEEYVDQLKWNSIIEDKIMKGLRPTIPNECPPDMKQLITDCWSGDPKKRPS 2027 Query 859 FRTILRDLTRLQ 870 F +IL L+ +Q Sbjct 2028 FNSILERLSTMQ 2039 >sp|Q8KY50|STKP_STREE Serine/threonine-protein kinase StkP OS=Streptococcus pneumoniae OX=1313 GN=stkP PE=1 SV=1 Length=659 Score = 83.2 bits (204), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 63/209 (30%), Positives = 100/209 (48%), Gaps = 11/209 (5%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEI 948 +F RY + ++ +G G V L D DG E VAVK L+ + P + +++E Sbjct 7 IFAGRY-RIVKQIGRGGMADVYL-AKDLILDG--EEVAVKVLRTNYQTDPIAVARFQREA 62 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQI 1007 + L H HI++ E+ G++ L MEYV L+ Y+ H + + + +QI Sbjct 63 RAMADLDHPHIVRITDIGEEDGQQ--YLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMRQI 120 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 M H + +HRDL +N+LL D K+ DFG+A A E G V + Sbjct 121 LLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVAFAETSLTQTNSMLGS--VHY 178 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096 +PE + K SD+++ G+ YE+LT Sbjct 179 LSPEQARGSKATVQSDIYAMGIIFYEMLT 207 Score = 35.0 bits (79), Expect = 5.0, Method: Compositional matrix adjust. Identities = 43/192 (22%), Positives = 87/192 (45%), Gaps = 27/192 (14%) Query 639 VVLKVLDPSHHD--IALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +KVL ++ IA+A F A M+ + H H+ + + + + EYV L Sbjct 39 VAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDL 98 Query 696 DVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 +++ H P++ + V +Q+ A+ + +VH ++ +NILL G A Sbjct 99 KRYIKE---HYPLSNEEAVRIMRQILLAMRLAHTRGIVHRDLKPQNILLTPDGTA----- 150 Query 754 FIKLSDPGVGLG----ALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLE-- 806 K++D G+ + +L++ + + +L+PE G ++ + D + G E Sbjct 151 --KVTDFGIAVAFAETSLTQTNSMLGSVHYLSPEQARGSKATVQS--DIYAMGIIFYEML 206 Query 807 ---ICFDGEAPL 815 I +DG++ + Sbjct 207 TGHIPYDGDSAV 218 >sp|Q6C3J2|IPL1_YARLI Spindle assembly checkpoint kinase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) OX=284591 GN=IPL1 PE=3 SV=1 Length=371 Score = 81.3 bits (199), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 64/225 (28%), Positives = 104/225 (46%), Gaps = 21/225 (9%) Query 879 TVNPDSPASDPTVFHKRYLKKI---RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--K 933 T +P SP + T F L + LG+G FGKV L + TG + A+K + K Sbjct 78 TTDPPSPLTGITGFRNYSLDDFEIGKALGKGKFGKVYLV----KDKKTGFVSALKCMEKK 133 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--- 990 +++E++I L H ++++ G D+ + L++EYV G L L Sbjct 134 ELVEGNVEKQFRREVEIQSNLRHTNVLRLFGHFHDKDR--VYLILEYVVHGELYKLLRNQ 191 Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 R + A ++ Q+ E + YLH ++ IHRD+ N+LL + +KI DFG + P Sbjct 192 KRFTESTASSYIY--QMSEALLYLHGKNIIHRDIKPENILLHFNDTIKISDFGWSVHAPS 249 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 R + + PE ++ + DVWS G+ +YE L Sbjct 250 NR-----RSTLCGTMDYLPPEIVQSRPYDKNVDVWSLGILMYEFL 289 Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 57/231 (25%), Positives = 97/231 (42%), Gaps = 23/231 (10%) Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 ++ F + S + HT++ + G ++ EYV HG L LR ++ Sbjct 139 NVEKQFRREVEIQSNLRHTNVLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTEST 198 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS- 768 + Q ++ AL YL KN++H ++ NILL + IK+SD G + A S Sbjct 199 ASSYIYQ-MSEALLYLHGKNIIHRDIKPENILLH-------FNDTIKISDFGWSVHAPSN 250 Query 769 -REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE-ICFDGEAPLQSRSPSEKEHF 826 R + +L PE + + +D W G + E +C G P + P + Sbjct 251 RRSTLCGTMDYLPPEIV--QSRPYDKNVDVWSLGILMYEFLC--GAPPFE--EPGGAQAT 304 Query 827 YQR----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD--LTRLQP 871 Y+R R+P A L + LT +P +R + + + + RL+P Sbjct 305 YRRIVKLDLRIPPYVSADAADLIKRMLTLDPAKRFKLKDMHKHPWIVRLRP 355 >sp|Q9LHP4|RGI1_ARATH LRR receptor-like serine/threonine-protein kinase RGI1 OS=Arabidopsis thaliana OX=3702 GN=RGI1 PE=1 SV=1 Length=1141 Score = 83.6 bits (205), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 90/298 (30%), Positives = 138/298 (46%), Gaps = 35/298 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQH-------RSGWKQEIDILRTL 954 +G+G G V Y D N GE++AVK L A H R + E+ L T+ Sbjct 792 IGKGCSGVV--YRADVDN---GEVIAVKKLWPAMVNGGHDEKTKNVRDSFSAEVKTLGTI 846 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLA-----QLLLFAQQIC 1008 H++I+++ GCC ++ + L+ +Y+P GSL L R L ++LL A Q Sbjct 847 RHKNIVRFLGCCWNRNTR--LLMYDYMPNGSLGSLLHERRGSSLDWDLRYRILLGAAQ-- 902 Query 1009 EGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 G+AYLH +HRD+ A N+L+ D I DFGLAK V EG + R Sbjct 903 -GLAYLHHDCLPPIVHRDIKANNILIGLDFEPYIADFGLAKLVDEG-DIGRCSNTVAGSY 960 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVL 1122 + APE K SDV+S+GV + E+LT D + ++ + +G + VL Sbjct 961 GYIAPEYGYSMKITEKSDVYSYGVVVLEVLTGKQPIDPTVPEGIHLVDWVRQNRGSLEVL 1020 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180 T L R E D+ +V C + RPT +++ +LK + ++ + A Sbjct 1021 DST-LRSRTE--AEADEM-MQVLGTALLCVNSSPDERPTMKDVAAMLKEIKQEREEYA 1074 Score = 34.7 bits (78), Expect = 6.8, Method: Compositional matrix adjust. Identities = 48/203 (24%), Positives = 84/203 (41%), Gaps = 29/203 (14%) Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D ++ +F + + H ++ G C +++ +Y+ +G L L RG Sbjct 826 DEKTKNVRDSFSAEVKTLGTIRHKNIVRFLGCCWNRNTRLLMYDYMPNGSLGSLLHERRG 885 Query 705 HVPMAWKMVVAQQLASA--LSYLENKNL---VHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + W + L +A L+YL + L VH ++ NIL +GL P+I Sbjct 886 S-SLDWDLRYRILLGAAQGLAYLHHDCLPPIVHRDIKANNIL---IGL--DFEPYI---- 935 Query 760 PGVGLGALSREERVERIP--------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 GL L E + R ++APE G + ++ D + +G +LE+ G Sbjct 936 ADFGLAKLVDEGDIGRCSNTVAGSYGYIAPEY--GYSMKITEKSDVYSYGVVVLEV-LTG 992 Query 812 EAPLQSRSPSEKEHF--YQRQHR 832 + P+ P E H + RQ+R Sbjct 993 KQPIDPTVP-EGIHLVDWVRQNR 1014 >sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo sapiens OX=9606 GN=NUAK1 PE=1 SV=1 Length=661 Score = 83.2 bits (204), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 58/197 (29%), Positives = 98/197 (50%), Gaps = 14/197 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960 LG+G +GKV T +G +VA+K+++ D Q ++EI+I+ +L H HII Sbjct 61 LGKGTYGKVK----RATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHII 116 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 E++ + + ++MEY G L DY+ R + + F +QI + Y H Sbjct 117 SIYEVFENKDK--IVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGV 174 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDL N+LLD++ +KI DFGL+ ++ + + + +PE + + Sbjct 175 VHRDLKLENILLDDNCNIKIADFGLSNL----YQKDKFLQTFCGSPLYASPEIVNGRPYR 230 Query 1080 YAS-DVWSFGVTLYELL 1095 D W+ GV LY L+ Sbjct 231 GPEVDSWALGVLLYTLV 247 Score = 37.0 bits (84), Expect = 1.2, Method: Compositional matrix adjust. Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 14/153 (9%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 +MS ++H H+ ++ V + +++ EY G L ++ ER + +Q+ S Sbjct 106 IMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYI-SERRRLSERETRHFFRQIVS 164 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---- 776 A+ Y +VH ++ NILL + IK++D GL L ++++ + Sbjct 165 AVHYCHKNGVVHRDLKLENILL-------DDNCNIKIAD--FGLSNLYQKDKFLQTFCGS 215 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 P A + G +D W G L + + Sbjct 216 PLYASPEIVNGRPYRGPEVDSWALGVLLYTLVY 248 >sp|Q9SXB4|Y1130_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g11300 OS=Arabidopsis thaliana OX=3702 GN=At1g11300 PE=2 SV=1 Length=820 Score = 83.2 bits (204), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 72/211 (34%), Positives = 98/211 (46%), Gaps = 22/211 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG P G G+ +AVK L G Q E+ ++ L H ++ Sbjct 515 LGQGGFG--------PVYKGKLQEGQEIAVKRLSRASG-QGLEELVNEVVVISKLQHRNL 565 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLF--AQQICEGMAYLH 1015 +K GCC E+ LV E++P SL YL R + L F IC G+ YLH Sbjct 566 VKLLGCCIAGEER--MLVYEFMPKKSLDYYLFDSRRAKLLDWKTRFNIINGICRGLLYLH 623 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 IHRDL A N+LLD + + KI DFGLA+ P + R + + APE Sbjct 624 RDSRLRIIHRDLKASNILLDENLIPKISDFGLARIFPGNEDEANTRRVVGTYGY-MAPEY 682 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 F SDV+S GV L E+++ +S S Sbjct 683 AMGGLFSEKSDVFSLGVILLEIISGRRNSNS 713 Score = 43.5 bits (101), Expect = 0.013, Method: Compositional matrix adjust. Identities = 57/226 (25%), Positives = 89/226 (39%), Gaps = 45/226 (20%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 + LGQG VY+G+L+ GQE+ V K L + Sbjct 513 NKLGQGGFGPVYKGKLQ-----------------------EGQEIAV--KRLSRASGQGL 547 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK- 711 ++S++ H +L + G C+ G E ++V E++ LD +L R + WK Sbjct 548 EELVNEVVVISKLQHRNLVKLLGCCIAGEERMLVYEFMPKKSLDYYLFDSRRAKLLDWKT 607 Query 712 -MVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LG 765 + + L YL + ++H ++ NIL L E P K+SD G+ Sbjct 608 RFNIINGICRGLLYLHRDSRLRIIHRDLKASNIL-----LDENLIP--KISDFGLARIFP 660 Query 766 ALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 E R+ ++APE GG S D + G LLEI Sbjct 661 GNEDEANTRRVVGTYGYMAPEYAMGGL--FSEKSDVFSLGVILLEI 704 >sp|Q4WHP3|STE20_ASPFU Serine/threonine-protein kinase ste20 OS=Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) OX=330879 GN=ste20 PE=3 SV=2 Length=815 Score = 83.2 bits (204), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 55/208 (26%), Positives = 98/208 (47%), Gaps = 14/208 (7%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DPT + K +G+G G V Y GT VA+K + D P+ + E Sbjct 529 DPTKLYYNLNK----IGQGASGGV----YTAYQHGTNNCVAIKQMNLDLQPK-KELIINE 579 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +++ H++I+ + + L +VMEY+ GSL D + + + Q+ ++ Sbjct 580 ILVMKDSKHKNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMTEGQIAAVCRET 637 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 G+ +LH++ IHRD+ + N+LL D +K+ DFG + ++ R +W Sbjct 638 LNGLQHLHSKGVIHRDIKSDNILLSLDGNIKLTDFGFCAQI---NDSQNKRNTMVGTPYW 694 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095 APE + ++ D+WS G+ E++ Sbjct 695 MAPEVVTRKEYGRKVDIWSLGIMAIEMI 722 Score = 37.0 bits (84), Expect = 1.4, Method: Compositional matrix adjust. Identities = 42/165 (25%), Positives = 69/165 (42%), Gaps = 18/165 (11%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719 +M H ++ + G + +V EY+E G L DV +A V ++ Sbjct 582 VMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVVTFNIMTEGQIA---AVCRETL 638 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERVER 775 + L +L +K ++H ++ NILL+ G IKL+D G + R V Sbjct 639 NGLQHLHSKGVIHRDIKSDNILLSLDG-------NIKLTDFGFCAQINDSQNKRNTMVGT 691 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 W+APE + +D W G +E+ +GE P + SP Sbjct 692 PYWMAPEVV--TRKEYGRKVDIWSLGIMAIEM-IEGEPPYLTESP 733 >sp|Q9SJG2|Y2296_ARATH Probable receptor-like protein kinase At2g42960 OS=Arabidopsis thaliana OX=3702 GN=At2g42960 PE=3 SV=1 Length=494 Score = 82.4 bits (202), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 81/284 (29%), Positives = 130/284 (46%), Gaps = 25/284 (9%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG +G V Y N G VAVK L + G Q ++ E++ + + H+++ Sbjct 186 VNVLGEGGYGVV--YRGKLVN---GTEVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNL 239 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYL 1014 ++ G C + + LV EYV G+L +L ++ + + +AYL Sbjct 240 VRLLGYCIEGVHR--MLVYEYVNSGNLEQWLHGAMRQHGNLTWEARMKIITGTAQALAYL 297 Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-AP 1070 H +HRD+ A N+L+D++ K+ DFGLAK + G + R G F Y AP Sbjct 298 HEAIEPKVVHRDIKASNILIDDEFNAKLSDFGLAKLLDSGESHITTRVMG---TFGYVAP 354 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E SD++SFGV L E +T D P + L+ + + R E+++ Sbjct 355 EYANTGLLNEKSDIYSFGVLLLEAITGRDPVDYGRPANEVNLVEWLKMMVGTRRAEEVVD 414 Query 1130 RGERL-PRPDKCPCEVYHLMK-NCWETEASFRPTFENLIPILKT 1171 RL PRP K + L+ C + EA RP + +L++ Sbjct 415 --PRLEPRPSKSALKRALLVSLRCVDPEAEKRPRMSQVARMLES 456 Score = 53.5 bits (127), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 61/234 (26%), Positives = 94/234 (40%), Gaps = 39/234 (17%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR---RERGHVPMAWKMVVAQQL 718 + V H +L + G C+ G ++V EYV G L+ WL R+ G++ +M + Sbjct 231 IGHVRHKNLVRLLGYCIEGVHRMLVYEYVNSGNLEQWLHGAMRQHGNLTWEARMKIITGT 290 Query 719 ASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE- 774 A AL+YL +VH ++ NIL+ A KLSD G+ S E + Sbjct 291 AQALAYLHEAIEPKVVHRDIKASNILIDDEFNA-------KLSDFGLAKLLDSGESHITT 343 Query 775 ----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-- 828 ++APE G L+ D + FG LLE G P+ P+ + + + Sbjct 344 RVMGTFGYVAPEYANTGL--LNEKSDIYSFGVLLLE-AITGRDPVDYGRPANEVNLVEWL 400 Query 829 ---------------RQHRLPEPSCPQLATLTS-QCLTYEPTQRPSFRTILRDL 866 R P S + A L S +C+ E +RP + R L Sbjct 401 KMMVGTRRAEEVVDPRLEPRPSKSALKRALLVSLRCVDPEAEKRPRMSQVARML 454 >sp|A9SR33|M2K1B_PHYPA Mitogen-activated protein kinase kinase 1b OS=Physcomitrium patens OX=3218 GN=MKK1b PE=2 SV=2 Length=342 Score = 80.9 bits (198), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 60/201 (30%), Positives = 100/201 (50%), Gaps = 13/201 (6%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ +R LG+G G V L + TND + A+K ++ + R QE+ I + H Sbjct 66 LEAVRVLGKGAGGSVQLVRHKWTND----IYALKGIQMNINETVRKQIVQELKINQLTLH 121 Query 957 E--HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAY 1013 + +I+K G + +V+EY+ GSL D + + I L + + Q+ +G+ Y Sbjct 122 QCPYIVKCYHSFYHNG--IISIVLEYMDRGSLADIIKQTKQIPEPYLAVISNQVLKGLNY 179 Query 1014 LH-AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 LH +H IHRD+ N+L++ VKI DFG++ + R+ + +PE Sbjct 180 LHQVRHIIHRDIKPSNLLINQKGEVKISDFGVSAVLISSMAQ---RDTFVGTYTYMSPER 236 Query 1073 LKEYKFYYASDVWSFGVTLYE 1093 L + Y SD+WS G+T+ E Sbjct 237 LGGQSYAYDSDIWSLGLTILE 257 >sp|Q8T0S6|HIPPO_DROME Serine/threonine-protein kinase hippo OS=Drosophila melanogaster OX=7227 GN=hpo PE=1 SV=1 Length=669 Score = 83.2 bits (204), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 54/194 (28%), Positives = 94/194 (48%), Gaps = 14/194 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG +G V Y + + +VA+K + + +EI I++ ++++Y Sbjct 48 LGEGSYGSV----YKAVHKESSSIVAIKLVPVESDLHE---IIKEISIMQQCDSPYVVRY 100 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G Q + L + MEY GS+ D L + ++ ++ +G+ YLH + I Sbjct 101 YGSYFKQYD--LWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKI 158 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 159 HRDIKAANILLNTEGYAKLADFGVAGQLTDT---MAKRNTVIGTPFWMAPEVIEEIGYDC 215 Query 1081 ASDVWSFGVTLYEL 1094 +D+WS G+T E+ Sbjct 216 VADIWSLGITALEM 229 Score = 41.6 bits (96), Expect = 0.046, Method: Compositional matrix adjust. Identities = 47/213 (22%), Positives = 83/213 (39%), Gaps = 20/213 (9%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S+M Q ++ +G + + + EY G + +R + + + Sbjct 87 SIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTL 146 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 L YL + +H ++ NILL T + KL+D GV +++ V Sbjct 147 QGLVYLHLRRKIHRDIKAANILL-------NTEGYAKLADFGVAGQLTDTMAKRNTVIGT 199 Query 777 P-WLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---- 830 P W+APE + G + ++ D W G T LE+ +G+ P P ++ Sbjct 200 PFWMAPEVIEEIGYDCVA---DIWSLGITALEMA-EGKPPYGEIHPMRAIFMIPQKPPPS 255 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 R P+ + S+CL EP R + +L Sbjct 256 FREPDRWSTEFIDFVSKCLVKEPDDRATATELL 288 >sp|C0LGV0|Y5487_ARATH Probable LRR receptor-like serine/threonine-protein kinase At5g48740 OS=Arabidopsis thaliana OX=3702 GN=At5g48740 PE=1 SV=1 Length=895 Score = 83.2 bits (204), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 71/249 (29%), Positives = 110/249 (44%), Gaps = 26/249 (10%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 QR R I R ++Q N + + + A+ R K++ +G G FG V Sbjct 573 QRNKERDITRAQLKMQNWNASRIFSHKEIKSAT-------RNFKEV--IGRGSFGAV--- 620 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 DG V V+ + G + E+ +L + H++++ ++G C + K Sbjct 621 YRGKLPDGKQVAVKVRFDRTQLGAD---SFINEVHLLSQIRHQNLVSFEGFCYE--PKRQ 675 Query 975 QLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAA 1026 LV EY+ GSL D+L RHS+ L A +G+ YLH IHRD+ + Sbjct 676 ILVYEYLSGGSLADHLYGPRSKRHSLNWVSRLKVAVDAAKGLDYLHNGSEPRIIHRDVKS 735 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 N+LLD D K+ DFGL+K + + + + PE + SDV+S Sbjct 736 SNILLDKDMNAKVSDFGLSKQFTKADASH-ITTVVKGTAGYLDPEYYSTLQLTEKSDVYS 794 Query 1087 FGVTLYELL 1095 FGV L EL+ Sbjct 795 FGVVLLELI 803 Score = 45.4 bits (106), Expect = 0.004, Method: Compositional matrix adjust. Identities = 53/179 (30%), Positives = 73/179 (41%), Gaps = 28/179 (16%) Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---RRERGHVPM 708 A +F L+SQ+ H +L G C I+V EY+ G L L R +R + Sbjct 644 ADSFINEVHLLSQIRHQNLVSFEGFCYEPKRQILVYEYLSGGSLADHLYGPRSKRHSLNW 703 Query 709 AWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 ++ VA A L YL N + ++H +V NILL + A K+SD GL Sbjct 704 VSRLKVAVDAAKGLDYLHNGSEPRIIHRDVKSSNILLDKDMNA-------KVSD--FGLS 754 Query 766 ALSREERVERIP--------WLAPECLPGGANSLSTAMDKWGFGATLLE-ICFDGEAPL 815 + I +L PE L+ D + FG LLE IC G PL Sbjct 755 KQFTKADASHITTVVKGTAGYLDPEYY--STLQLTEKSDVYSFGVVLLELIC--GREPL 809 >sp|P13185|KIN1_YEAST Serine/threonine protein kinase KIN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=KIN1 PE=1 SV=3 Length=1064 Score = 83.6 bits (205), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 71/242 (29%), Positives = 105/242 (43%), Gaps = 47/242 (19%) Query 889 PTVFHKRYLKK---IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW- 944 P FH++ L + +G G GKV L + TN+ + +A KA H+ Sbjct 109 PKQFHRKSLGDWEFVETVGAGSMGKVKLAKHRYTNEVCAVKIVNRATKAFL---HKEQML 165 Query 945 ---KQEIDIL-----------------------RTLYHEHIIKYKGCCEDQGEKSLQLVM 978 K E D+L + LYH HI + C ++ Sbjct 166 PPPKNEQDVLERQKKLEKEISRDKRTIREASLGQILYHPHICRLFEMCTLSNH--FYMLF 223 Query 979 EYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037 EYV G L DY+ +H SI Q FA+ I + YLHA + +HRDL N+++ + + Sbjct 224 EYVSGGQLLDYIIQHGSIREHQARKFARGIASALIYLHANNIVHRDLKIENIMISDSSEI 283 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDS---PVFWYAPECLKEYKFYYAS-DVWSFGVTLYE 1093 KI DFGL+ Y R+ + +++ APE LK + DVWSFGV L+ Sbjct 284 KIIDFGLSN-------IYDSRKQLHTFCGSLYFAAPELLKANPYTGPEVDVWSFGVVLFV 336 Query 1094 LL 1095 L+ Sbjct 337 LV 338 Score = 47.4 bits (111), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 52/209 (25%), Positives = 92/209 (44%), Gaps = 14/209 (7%) Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQL 718 ASL + H H+ + +C M+ EYV G L ++ + G + A+ + Sbjct 195 ASLGQILYHPHICRLFEMCTLSNHFYMLFEYVSGGQLLDYII-QHGSIREHQARKFARGI 253 Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER---VER 775 ASAL YL N+VH ++ NI+++ S IK+ D G+ SR++ Sbjct 254 ASALIYLHANNIVHRDLKIENIMIS-------DSSEIKIIDFGLSNIYDSRKQLHTFCGS 306 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE-KEHFYQRQHRLP 834 + + APE L + +D W FG L + G+ P + S E Q + P Sbjct 307 LYFAAPELLKANPYT-GPEVDVWSFGVVLF-VLVCGKVPFDDENSSVLHEKIKQGKVEYP 364 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 + ++ +L S+ L +P +R + + ++ Sbjct 365 QHLSIEVISLLSKMLVVDPKRRATLKQVV 393 >sp|F1LP90|MINK1_RAT Misshapen-like kinase 1 OS=Rattus norvegicus OX=10116 GN=Mink1 PE=1 SV=2 Length=1336 Score = 83.6 bits (205), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 62/206 (30%), Positives = 101/206 (49%), Gaps = 24/206 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961 +G G +G+V Y + TG++ A+K + D KQEI++L+ +H +I Sbjct 31 VGNGTYGQV----YKGRHVKTGQLAAIKVM--DVTEDEEEEIKQEINMLKKYSHHRNIAT 84 Query 962 YKGCCEDQ----GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ----LLLFAQQICEGMAY 1013 Y G + + L LVME+ GS+ D L +++ G A + ++I G+A+ Sbjct 85 YYGAFIKKSPPGNDDQLWLVMEFCGAGSVTD-LVKNTKGNALKEDCIAYICREILRGLAH 143 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 LHA IHRD+ +NVLL + VK+ DFG++ + R +W APE + Sbjct 144 LHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---DRTVGRRNTFIGTPYWMAPEVI 200 Query 1074 K-----EYKFYYASDVWSFGVTLYEL 1094 + + Y SD+WS G+T E+ Sbjct 201 ACDENPDATYDYRSDIWSLGITAIEM 226 Score = 37.0 bits (84), Expect = 1.4, Method: Compositional matrix adjust. Identities = 42/191 (22%), Positives = 80/191 (42%), Gaps = 22/191 (12%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG--PENI----MVTEYVEH 692 +KV+D + + E L H ++A +G ++ P N +V E+ Sbjct 51 AAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGA 110 Query 693 GPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G + ++ +G+ + + +++ L++L ++H ++ G+N+LL Sbjct 111 GSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTE------- 163 Query 752 SPFIKLSDPGVGLG---ALSREERVERIP-WLAPECLPGGANSLST---AMDKWGFGATL 804 + +KL D GV + R P W+APE + N +T D W G T Sbjct 164 NAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITA 223 Query 805 LEICFDGEAPL 815 +E+ +G PL Sbjct 224 IEMA-EGAPPL 233 >sp|A0A2I0BVG8|CDPK1_PLAFO Calcium-dependent protein kinase 1 OS=Plasmodium falciparum (isolate NF54) OX=5843 GN=PDCK1 PE=1 SV=1 Length=524 Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 67/212 (32%), Positives = 100/212 (47%), Gaps = 23/212 (11%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK-----------ALKADCGPQHRSGWKQE 947 K+R LG G +G+V L C + G + +K K +C + E Sbjct 58 KVRKLGSGAYGEV-LLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEIYNE 116 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQ 1006 I +L++L H +IIK ED+ K LV E+ G L + RH +Q Sbjct 117 ISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQ 174 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDS 1063 I G+ YLH + +HRD+ N+LL+N +KI DFGL+ + + ++R D Sbjct 175 ILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDN---KLR-DRLG 230 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 ++ APE L++ K+ DVWS GV LY LL Sbjct 231 TAYYIAPEVLRK-KYNEKCDVWSCGVILYILL 261 Score = 38.5 bits (88), Expect = 0.41, Method: Compositional matrix adjust. Identities = 54/232 (23%), Positives = 90/232 (39%), Gaps = 29/232 (13%) Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVWLRRE 702 D H +I Y SL+ + H ++ + V +VTE+ E G L + R + Sbjct 107 DKIHEEI----YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHK 162 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 A + +Q+ S + YL N+VH ++ NILL E + + Sbjct 163 FDECDAA---NIMKQILSGICYLHKHNIVHRDIKPENILL------ENKHSLLNIKIVDF 213 Query 763 GLGA-LSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATL-LEIC----FDGE 812 GL + S++ +R+ ++APE L N D W G L + +C F G+ Sbjct 214 GLSSFFSKDNKLRDRLGTAYYIAPEVLRKKYNE---KCDVWSCGVILYILLCGYPPFGGQ 270 Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 EK +Y + S + L LTY+ +R + + L Sbjct 271 NDQDIIKKVEKGKYYFDFNDWKNIS-EEAKELIKLMLTYDYNKRITAKEALN 321 >sp|P62343|CDPK1_PLAFK Calcium-dependent protein kinase 1 OS=Plasmodium falciparum (isolate K1 / Thailand) OX=5839 GN=CDPK1 PE=1 SV=2 Length=524 Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 67/212 (32%), Positives = 100/212 (47%), Gaps = 23/212 (11%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK-----------ALKADCGPQHRSGWKQE 947 K+R LG G +G+V L C + G + +K K +C + E Sbjct 58 KVRKLGSGAYGEV-LLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEIYNE 116 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQ 1006 I +L++L H +IIK ED+ K LV E+ G L + RH +Q Sbjct 117 ISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQ 174 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDS 1063 I G+ YLH + +HRD+ N+LL+N +KI DFGL+ + + ++R D Sbjct 175 ILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDN---KLR-DRLG 230 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 ++ APE L++ K+ DVWS GV LY LL Sbjct 231 TAYYIAPEVLRK-KYNEKCDVWSCGVILYILL 261 Score = 38.5 bits (88), Expect = 0.41, Method: Compositional matrix adjust. Identities = 54/232 (23%), Positives = 90/232 (39%), Gaps = 29/232 (13%) Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVWLRRE 702 D H +I Y SL+ + H ++ + V +VTE+ E G L + R + Sbjct 107 DKIHEEI----YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHK 162 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 A + +Q+ S + YL N+VH ++ NILL E + + Sbjct 163 FDECDAA---NIMKQILSGICYLHKHNIVHRDIKPENILL------ENKHSLLNIKIVDF 213 Query 763 GLGA-LSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATL-LEIC----FDGE 812 GL + S++ +R+ ++APE L N D W G L + +C F G+ Sbjct 214 GLSSFFSKDNKLRDRLGTAYYIAPEVLRKKYNE---KCDVWSCGVILYILLCGYPPFGGQ 270 Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 EK +Y + S + L LTY+ +R + + L Sbjct 271 NDQDIIKKVEKGKYYFDFNDWKNIS-EEAKELIKLMLTYDYNKRITAKEALN 321 >sp|P62344|CDPK1_PLAF7 Calcium-dependent protein kinase 1 OS=Plasmodium falciparum (isolate 3D7) OX=36329 GN=CDPK1 PE=1 SV=2 Length=524 Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 67/212 (32%), Positives = 100/212 (47%), Gaps = 23/212 (11%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK-----------ALKADCGPQHRSGWKQE 947 K+R LG G +G+V L C + G + +K K +C + E Sbjct 58 KVRKLGSGAYGEV-LLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEIYNE 116 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL-RDYLPRHSIGLAQLLLFAQQ 1006 I +L++L H +IIK ED+ K LV E+ G L + RH +Q Sbjct 117 ISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQ 174 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDS 1063 I G+ YLH + +HRD+ N+LL+N +KI DFGL+ + + ++R D Sbjct 175 ILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDN---KLR-DRLG 230 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 ++ APE L++ K+ DVWS GV LY LL Sbjct 231 TAYYIAPEVLRK-KYNEKCDVWSCGVILYILL 261 Score = 38.5 bits (88), Expect = 0.41, Method: Compositional matrix adjust. Identities = 54/232 (23%), Positives = 90/232 (39%), Gaps = 29/232 (13%) Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVWLRRE 702 D H +I Y SL+ + H ++ + V +VTE+ E G L + R + Sbjct 107 DKIHEEI----YNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHK 162 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 A + +Q+ S + YL N+VH ++ NILL E + + Sbjct 163 FDECDAA---NIMKQILSGICYLHKHNIVHRDIKPENILL------ENKHSLLNIKIVDF 213 Query 763 GLGA-LSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATL-LEIC----FDGE 812 GL + S++ +R+ ++APE L N D W G L + +C F G+ Sbjct 214 GLSSFFSKDNKLRDRLGTAYYIAPEVLRKKYNE---KCDVWSCGVILYILLCGYPPFGGQ 270 Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 EK +Y + S + L LTY+ +R + + L Sbjct 271 NDQDIIKKVEKGKYYFDFNDWKNIS-EEAKELIKLMLTYDYNKRITAKEALN 321 >sp|Q7YQL3|PAK3_PONPY Serine/threonine-protein kinase PAK 3 OS=Pongo pygmaeus OX=9600 GN=PAK3 PE=2 SV=1 Length=559 Score = 82.8 bits (203), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 59/209 (28%), Positives = 98/209 (47%), Gaps = 16/209 (8%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP + R+ K +G+G G V Y + TG+ VA+K + P+ + E Sbjct 278 DPKKKYTRFEK----IGQGASGTV----YTALDIATGQEVAIKQMNLQQQPK-KELIINE 328 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I ++R + +I+ Y E L +VMEY+ GSL D + + Q+ ++ Sbjct 329 ILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCREC 386 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066 + + +LH+ IHRD+ + N+LL D VK+ DFG A+ PE + R + Sbjct 387 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 442 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095 W APE + + D+WS G+ E++ Sbjct 443 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 471 >sp|Q7YQL4|PAK3_PANTR Serine/threonine-protein kinase PAK 3 OS=Pan troglodytes OX=9598 GN=PAK3 PE=2 SV=1 Length=559 Score = 82.8 bits (203), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 59/209 (28%), Positives = 98/209 (47%), Gaps = 16/209 (8%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP + R+ K +G+G G V Y + TG+ VA+K + P+ + E Sbjct 278 DPKKKYTRFEK----IGQGASGTV----YTALDIATGQEVAIKQMNLQQQPK-KELIINE 328 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I ++R + +I+ Y E L +VMEY+ GSL D + + Q+ ++ Sbjct 329 ILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCREC 386 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066 + + +LH+ IHRD+ + N+LL D VK+ DFG A+ PE + R + Sbjct 387 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 442 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095 W APE + + D+WS G+ E++ Sbjct 443 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 471 >sp|O75914|PAK3_HUMAN Serine/threonine-protein kinase PAK 3 OS=Homo sapiens OX=9606 GN=PAK3 PE=1 SV=2 Length=559 Score = 82.8 bits (203), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 59/209 (28%), Positives = 98/209 (47%), Gaps = 16/209 (8%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP + R+ K +G+G G V Y + TG+ VA+K + P+ + E Sbjct 278 DPKKKYTRFEK----IGQGASGTV----YTALDIATGQEVAIKQMNLQQQPK-KELIINE 328 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I ++R + +I+ Y E L +VMEY+ GSL D + + Q+ ++ Sbjct 329 ILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCREC 386 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066 + + +LH+ IHRD+ + N+LL D VK+ DFG A+ PE + R + Sbjct 387 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 442 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095 W APE + + D+WS G+ E++ Sbjct 443 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 471 >sp|Q09170|CDS1_SCHPO Serine/threonine-protein kinase cds1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=cds1 PE=1 SV=2 Length=460 Score = 82.0 bits (201), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 77/244 (32%), Positives = 111/244 (45%), Gaps = 19/244 (8%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAV----KALKADCGPQHRSGWKQEIDILRTLY 955 IR LG G F V L N G + + K L + +++EIDIL++L+ Sbjct 170 IRTLGSGTFAVVKLAV--EVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSLH 227 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYL 1014 H +++ E+ E L +VMEYV G L D+L + SI +Q+ E + +L Sbjct 228 HPGVVQCHEIFENDDE--LFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHL 285 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H Q HRD+ N+L+ ND +KI DFGLAK + H E + + APE LK Sbjct 286 HKQGVTHRDIKPENILITNDFHLKISDFGLAKVI---HGTGTFLETFCGTMGYLAPEVLK 342 Query 1075 EYK------FYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 + D+WS G LY +LT + S K +ELI + L E+ Sbjct 343 SKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQAKCIELISKGAYPIEPLLENEI 402 Query 1128 LERG 1131 E G Sbjct 403 SEEG 406 >sp|Q62829|PAK3_RAT Serine/threonine-protein kinase PAK 3 OS=Rattus norvegicus OX=10116 GN=Pak3 PE=1 SV=1 Length=544 Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 59/209 (28%), Positives = 98/209 (47%), Gaps = 16/209 (8%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP + R+ K +G+G G V Y + TG+ VA+K + P+ + E Sbjct 263 DPKKKYTRFEK----IGQGASGTV----YTALDIATGQEVAIKQMNLQQQPK-KELIINE 313 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I ++R + +I+ Y E L +VMEY+ GSL D + + Q+ ++ Sbjct 314 ILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCREC 371 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066 + + +LH+ IHRD+ + N+LL D VK+ DFG A+ PE + R + Sbjct 372 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 427 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095 W APE + + D+WS G+ E++ Sbjct 428 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 456 Score = 33.9 bits (76), Expect = 9.7, Method: Compositional matrix adjust. Identities = 40/150 (27%), Positives = 64/150 (43%), Gaps = 26/150 (17%) Query 680 GPENIMVTEYVEHGPL-DVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736 G E +V EY+ G L DV + G + V ++ AL +L + ++H ++ Sbjct 335 GDELWVVMEYLAGGSLTDVVTETCMDEGQI-----AAVCRECLQALDFLHSNQVIHRDIK 389 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANS 790 NILL G +KL+D G A E+ +R W+APE + A Sbjct 390 SDNILL-------GMDGSVKLTD--FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-- 438 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +D W G +E+ +GE P + +P Sbjct 439 YGPKVDIWSLGIMAIEMV-EGEPPYLNENP 467 >sp|Q942F3|BRI1_ORYSJ Brassinosteroid LRR receptor kinase BRI1 OS=Oryza sativa subsp. japonica OX=39947 GN=BRI1 PE=1 SV=1 Length=1121 Score = 83.6 bits (205), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 81/288 (28%), Positives = 132/288 (46%), Gaps = 33/288 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V G++VA+K L G R + E++ + + H +++ Sbjct 813 IGSGGFGDVY-----KAQLKDGKVVAIKKLIHVSGQGDRE-FTAEMETIGKIKHRNLVPL 866 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQIC----EGMAYLHAQ 1017 G C+ GE+ L LV +Y+ GSL D L R IG ++I G+A+LH Sbjct 867 LGYCK-AGEERL-LVYDYMKFGSLEDVLHDRKKIGKKLNWEARRKIAVGAARGLAFLHHN 924 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H IHRD+ + NVL+D ++ DFG+A+ + + V +P + PE + Sbjct 925 CIPHIIHRDMKSSNVLIDEQLEARVSDFGMARLMSVVDTHLSVSTLAGTPGY-VPPEYYQ 983 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE------LIGIAQGQMTVLRLTELL 1128 ++ DV+S+GV L ELLT PPT + L+G + Q T L++T++ Sbjct 984 SFRCTTKGDVYSYGVVLLELLTG-----KPPTDSADFGEDNNLVGWVK-QHTKLKITDVF 1037 Query 1129 ERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILKTVH 1173 + E L E+ +K C + S RPT ++ + K + Sbjct 1038 DP-ELLKEDPSVELELLEHLKIACACLDDRPSRRPTMLKVMAMFKEIQ 1084 Score = 35.4 bits (80), Expect = 4.5, Method: Compositional matrix adjust. Identities = 52/264 (20%), Positives = 110/264 (42%), Gaps = 39/264 (15%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAW--K 711 F + ++ H +L + G C G E ++V +Y++ G L DV R++ + W + Sbjct 848 FTAEMETIGKIKHRNLVPLLGYCKAGEERLLVYDYMKFGSLEDVLHDRKKIGKKLNWEAR 907 Query 712 MVVAQQLASALSYLENK---NLVHGNVCGRNILL-----ARLGLAEGTSPFIKLSDPGVG 763 +A A L++L + +++H ++ N+L+ AR+ G + + + D + Sbjct 908 RKIAVGAARGLAFLHHNCIPHIIHRDMKSSNVLIDEQLEARVS-DFGMARLMSVVDTHLS 966 Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + L+ ++ PE + +T D + +G LLE+ G+ P S E Sbjct 967 VSTLAGTP-----GYVPPEYYQ--SFRCTTKGDVYSYGVVLLEL-LTGKPPTDSADFGED 1018 Query 824 EHF--YQRQH---RLPEPSCPQL--------------ATLTSQCLTYEPTQRPSFRTILR 864 + + +QH ++ + P+L + CL P++RP+ ++ Sbjct 1019 NNLVGWVKQHTKLKITDVFDPELLKEDPSVELELLEHLKIACACLDDRPSRRPTMLKVMA 1078 Query 865 DLTRLQPHNLADVLTVNPDSPASD 888 +Q + D T + + + D Sbjct 1079 MFKEIQAGSTVDSKTSSAAAGSID 1102 >sp|O22971|CIPKD_ARATH CBL-interacting serine/threonine-protein kinase 13 OS=Arabidopsis thaliana OX=3702 GN=CIPK13 PE=1 SV=2 Length=502 Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 76/233 (33%), Positives = 115/233 (49%), Gaps = 33/233 (14%) Query 879 TVNPDSPASDPT-----VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933 T P+SP S T + K + K+ LG G F KV Y N +GE VA+K + Sbjct 36 TSTPESPRSPRTPQGSILMDKYEIGKL--LGHGSFAKV----YLARNIHSGEDVAIKVI- 88 Query 934 ADCGPQHRSGW----KQEIDILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRD 988 D +SG K+EI ILR + H +I+ E K+ + +VMEYV G L + Sbjct 89 -DKEKIVKSGLAGHIKREISILRRVRHPYIVH---LLEVMATKTKIYIVMEYVRGGELYN 144 Query 989 YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + R + + QQ+ +A+ H++ HRDL N+LLD+ VK+ DFGL+ V Sbjct 145 TVARGRLREGTARRYFQQLISSVAFCHSRGVYHRDLKLENLLLDDKGNVKVSDFGLS-VV 203 Query 1049 PEGHEYYRVREDGDSPVF-----WYAPECLKEYKFYYA-SDVWSFGVTLYELL 1095 E +++++G F + APE L + A +D+WS GV L+ L+ Sbjct 204 SE-----QLKQEGICQTFCGTPAYLAPEVLTRKGYEGAKADIWSCGVILFVLM 251 Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 76/304 (25%), Positives = 125/304 (41%), Gaps = 49/304 (16%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 SPRT S L +D+ EI +L LG G+ VY R SG+ K+ D++ +V Sbjct 44 SPRTPQGSIL----MDKYEIGKL--LGHGSFAKVYLAR--NIHSGEDVAIKVIDKEKIVK 95 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G R + S++ +V H ++ + V + +V EY Sbjct 96 SGLAGHIKREI-------------------SILRRVRHPYIVHLLEVMATKTKIYIVMEY 136 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 V G L + R R A + QQL S++++ ++ + H ++ N+LL G Sbjct 137 VRGGELYNTVARGRLREGTARRYF--QQLISSVAFCHSRGVYHRDLKLENLLLDDKG--- 191 Query 750 GTSPFIKLSDPGVGLGALSREERVERI--------PWLAPECLPGGANSLSTAMDKWGFG 801 +K+SD GL +S + + E I +LAPE L + A D W G Sbjct 192 ----NVKVSD--FGLSVVSEQLKQEGICQTFCGTPAYLAPEVLTRKGYEGAKA-DIWSCG 244 Query 802 ATLLEICFDGEAPLQSRSP-SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 L + G P ++ Y+ Q + P+ P+LA L ++ L P R + Sbjct 245 VILF-VLMAGYLPFDDKNILVMYTKIYKGQFKCPKWFSPELARLVTRMLDTNPDTRITIP 303 Query 861 TILR 864 I++ Sbjct 304 EIMK 307 >sp|O64781|Y1639_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61390 OS=Arabidopsis thaliana OX=3702 GN=At1g61390 PE=3 SV=1 Length=831 Score = 83.2 bits (204), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 66/203 (33%), Positives = 99/203 (49%), Gaps = 22/203 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG P G G+ +AVK L + G Q + EI ++ L H+++ Sbjct 526 LGQGGFG--------PVYKGKLVDGKEIAVKRLSSSSG-QGTDEFMNEIRLISKLQHKNL 576 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015 ++ GCC +GE+ L L+ EY+ SL +L + I + Q + G+ YLH Sbjct 577 VRLLGCCI-KGEEKL-LIYEYLVNKSLDVFLFDSTLKFEIDWQKRFNIIQGVARGLLYLH 634 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 IHRDL N+LLD + KI DFGLA+ + +G +Y + + APE Sbjct 635 RDSRLRVIHRDLKVSNILLDEKMIPKISDFGLAR-MSQGTQYQDNTRRVVGTLGYMAPEY 693 Query 1073 LKEYKFYYASDVWSFGVTLYELL 1095 F SD++SFGV L E++ Sbjct 694 AWTGVFSEKSDIYSFGVLLLEII 716 Score = 57.0 bits (136), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 61/244 (25%), Positives = 103/244 (42%), Gaps = 43/244 (18%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 +NL + R + + LGQG VY+G+L V G++ Sbjct 505 VNLFDMHTIRTATNNFSSSNKLGQGGFGPVYKGKL-------------------VDGKE- 544 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + +K L S F L+S++ H +L + G C++G E +++ EY+ + Sbjct 545 -----IAVKRLSSSSGQGTDEFMNEIRLISKLQHKNLVRLLGCCIKGEEKLLIYEYLVNK 599 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 LDV+L + W + + Q +A L YL + + V R++ ++ + L E Sbjct 600 SLDVFLFDSTLKFEIDWQKRFNIIQGVARGLLYLHRDSRLR--VIHRDLKVSNILLDEKM 657 Query 752 SPFIKLSDPGVGLGALSREER--------VERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 P K+SD GL +S+ + V + ++APE G S D + FG Sbjct 658 IP--KISD--FGLARMSQGTQYQDNTRRVVGTLGYMAPEYAWTGV--FSEKSDIYSFGVL 711 Query 804 LLEI 807 LLEI Sbjct 712 LLEI 715 >sp|A4IFM7|MYLK2_BOVIN Myosin light chain kinase 2, skeletal/cardiac muscle OS=Bos taurus OX=9913 GN=MYLK2 PE=2 SV=1 Length=623 Score = 82.8 bits (203), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 61/198 (31%), Positives = 99/198 (50%), Gaps = 15/198 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V C T TG +A K +K P+ + EI+++ L H ++I+ Sbjct 318 LGGGKFGAV-CTC---TEKATGLKLAAKVIKKQT-PKDKEMVLLEIEVMNQLNHRNLIQL 372 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020 E E + L MEY+ G L + + L ++ ++F +QIC+G+ ++H + Sbjct 373 YAAIETPHE--IVLFMEYIEGGELFERIVDEDYQLTEVDTMVFVRQICDGILFMHKMRVL 430 Query 1021 HRDLAARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 H DL N+L N LVKI DFGLA+ + +++ + +P F +PE + + Sbjct 431 HLDLKPENILCVNTTGHLVKIIDFGLARRY---NPNEKLKVNFGTPEF-LSPEVVNYDQI 486 Query 1079 YYASDVWSFGVTLYELLT 1096 +D+WS GV Y LL+ Sbjct 487 SDKTDMWSLGVITYMLLS 504 Score = 34.7 bits (78), Expect = 7.1, Method: Compositional matrix adjust. Identities = 38/172 (22%), Positives = 69/172 (40%), Gaps = 27/172 (16%) Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 V+K P ++ L E +M+Q++H +L ++ E ++ EY+E G L + Sbjct 342 VIKKQTPKDKEMVLLEIE---VMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERI 398 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL----------LARLGLAE 749 E + MV +Q+ + ++ ++H ++ NIL + GLA Sbjct 399 VDEDYQLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLAR 458 Query 750 GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 +P KL V G +L+PE + + +S D W G Sbjct 459 RYNPNEKLK---VNFGTPE---------FLSPEVV--NYDQISDKTDMWSLG 496 >sp|Q8SRF5|Y823_ENCCU Probable cell division protein kinase ECU08_0230 OS=Encephalitozoon cuniculi (strain GB-M1) OX=284813 GN=ECU08_0230 PE=3 SV=1 Length=265 Score = 79.3 bits (194), Expect = 9e-15, Method: Composition-based stats. Identities = 61/202 (30%), Positives = 100/202 (50%), Gaps = 27/202 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G +G+V Y+ + T E VA+K ++ + +EI IL+ L H +II Sbjct 10 IGSGTYGEV----YEAIDTETKEKVALKRIRLNEKEGMPGTALREISILKKLSHRNIISL 65 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ----LLLFAQQICEGMAYLHAQH 1018 + L +V ++ DY + IG+ + L Q IC G+ YLH + Sbjct 66 VSII--HTDALLTMVFPFI------DYELKKYIGMNTGKNIMELVNQLIC-GVHYLHRMN 116 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECL---K 1074 +HRDL +N+L+ +D ++KI DFGL++++ E + WY +PE L Sbjct 117 VVHRDLKPQNILVTSDGVLKIADFGLSRSL----EIRVPPYSSEVVTLWYRSPELLMGST 172 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 Y+FY D+WS G +YE++T Sbjct 173 SYRFYV--DIWSLGCIIYEMIT 192 >sp|Q9LYN8|EMS1_ARATH Leucine-rich repeat receptor protein kinase EMS1 OS=Arabidopsis thaliana OX=3702 GN=EMS1 PE=1 SV=1 Length=1192 Score = 83.6 bits (205), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 69/212 (33%), Positives = 104/212 (49%), Gaps = 24/212 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTL 954 + K +G+G FG V C GE VAVK L ++ Q + E++ L + Sbjct 916 HFSKKNIIGDGGFGTVYKACL------PGEKTVAVKKL-SEAKTQGNREFMAEMETLGKV 968 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI------C 1008 H +++ G C EK LV EY+ GSL +L R+ G+ ++L +++++ Sbjct 969 KHPNLVSLLGYCSFSEEK--LLVYEYMVNGSLDHWL-RNQTGMLEVLDWSKRLKIAVGAA 1025 Query 1009 EGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 G+A+LH H IHRD+ A N+LLD D K+ DFGLA+ + + G Sbjct 1026 RGLAFLHHGFIPHIIHRDIKASNILLDGDFEPKVADFGLARLISACESHVSTVIAG---T 1082 Query 1066 FWYA-PECLKEYKFYYASDVWSFGVTLYELLT 1096 F Y PE + + DV+SFGV L EL+T Sbjct 1083 FGYIPPEYGQSARATTKGDVYSFGVILLELVT 1114 Score = 47.4 bits (111), Expect = 0.001, Method: Compositional matrix adjust. Identities = 63/264 (24%), Positives = 111/264 (42%), Gaps = 40/264 (15%) Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 E V +K L + F + +V H +L + G C E ++V EY+ +G L Sbjct 939 EKTVAVKKLSEAKTQGNREFMAEMETLGKVKHPNLVSLLGYCSFSEEKLLVYEYMVNGSL 998 Query 696 DVWLRRERGHVP-MAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAE 749 D WLR + G + + W ++ +A A L++L + +++H ++ NILL + Sbjct 999 DHWLRNQTGMLEVLDWSKRLKIAVGAARGLAFLHHGFIPHIIHRDIKASNILL------D 1052 Query 750 GT-SPFIKLSDPGVGLGALSREERVERI-----PWLAPECLPGGANSLSTAMDKWGFGAT 803 G P K++D G+ + E V + ++ PE G + +T D + FG Sbjct 1053 GDFEP--KVADFGLARLISACESHVSTVIAGTFGYIPPEY--GQSARATTKGDVYSFGVI 1108 Query 804 LLEICFDGEAPLQSRSPSEKEHF----YQRQHR-----LPEPSCPQLATLTSQ------- 847 LLE+ E SE + Q+ ++ + +P +A SQ Sbjct 1109 LLELVTGKEPTGPDFKESEGGNLVGWAIQKINQGKAVDVIDPLLVSVALKNSQLRLLQIA 1168 Query 848 --CLTYEPTQRPSFRTILRDLTRL 869 CL P +RP+ +L+ L + Sbjct 1169 MLCLAETPAKRPNMLDVLKALKEI 1192 >sp|Q61036|PAK3_MOUSE Serine/threonine-protein kinase PAK 3 OS=Mus musculus OX=10090 GN=Pak3 PE=1 SV=2 Length=559 Score = 82.4 bits (202), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 59/209 (28%), Positives = 98/209 (47%), Gaps = 16/209 (8%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP + R+ K +G+G G V Y + TG+ VA+K + P+ + E Sbjct 278 DPKKKYTRFEK----IGQGASGTV----YTALDIATGQEVAIKQMNLQQQPK-KELIINE 328 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I ++R + +I+ Y E L +VMEY+ GSL D + + Q+ ++ Sbjct 329 ILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCREC 386 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL-AKAVPEGHEYYRVREDGDSPVF 1066 + + +LH+ IHRD+ + N+LL D VK+ DFG A+ PE + R + Sbjct 387 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK----RSTMVGTPY 442 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELL 1095 W APE + + D+WS G+ E++ Sbjct 443 WMAPEVVTRKAYGPKVDIWSLGIMAIEMV 471 Score = 34.3 bits (77), Expect = 9.3, Method: Compositional matrix adjust. Identities = 40/150 (27%), Positives = 64/150 (43%), Gaps = 26/150 (17%) Query 680 GPENIMVTEYVEHGPL-DVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736 G E +V EY+ G L DV + G + V ++ AL +L + ++H ++ Sbjct 350 GDELWVVMEYLAGGSLTDVVTETCMDEGQI-----AAVCRECLQALDFLHSNQVIHRDIK 404 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANS 790 NILL G +KL+D G A E+ +R W+APE + A Sbjct 405 SDNILL-------GMDGSVKLTD--FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA-- 453 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +D W G +E+ +GE P + +P Sbjct 454 YGPKVDIWSLGIMAIEMV-EGEPPYLNENP 482 >sp|Q4KM47|CDK10_RAT Cyclin-dependent kinase 10 OS=Rattus norvegicus OX=10116 GN=Cdk10 PE=2 SV=1 Length=358 Score = 80.9 bits (198), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 70/214 (33%), Positives = 101/214 (47%), Gaps = 26/214 (12%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDI 950 + +K+ +GEG +G V Y + T E+VA+K ++ D + + G +EI + Sbjct 35 KEFEKLNRIGEGTYGIV----YRARDTQTDEIVALKKVRMD---KEKDGIPISSLREITL 87 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQIC 1008 L L H +I++ K +S+ LVM Y L SL + +P AQ+ Q+ Sbjct 88 LLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPT-PFSEAQVKCILLQVL 146 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP---V 1065 G+ YLH IHRDL N+L+ + VK DFGLA+A Y V +P Sbjct 147 RGLQYLHRSFIIHRDLKVSNLLMTDKGCVKTADFGLARA-------YGVPVKPMTPKVVT 199 Query 1066 FWY-APECLKEYKFYYAS-DVWSFGVTLYELLTH 1097 WY APE L S D+W+ G L ELL H Sbjct 200 LWYRAPELLLGTTTQTTSIDMWAVGCILAELLAH 233 >sp|P07313|MYLK2_RABIT Myosin light chain kinase 2, skeletal/cardiac muscle OS=Oryctolagus cuniculus OX=9986 GN=MYLK2 PE=1 SV=3 Length=608 Score = 82.8 bits (203), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 61/198 (31%), Positives = 99/198 (50%), Gaps = 15/198 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V C T TG +A K +K P+ + EI+++ L H ++I+ Sbjct 303 LGGGKFGAV-CTC---TEKSTGLKLAAKVIKKQT-PKDKEMVMLEIEVMNQLNHRNLIQL 357 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020 E E + L MEY+ G L + + L ++ ++F +QIC+G+ ++H + Sbjct 358 YAAIETPHE--IVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVL 415 Query 1021 HRDLAARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 H DL N+L N LVKI DFGLA+ + +++ + +P F +PE + + Sbjct 416 HLDLKPENILCVNTTGHLVKIIDFGLARRY---NPNEKLKVNFGTPEF-LSPEVVNYDQI 471 Query 1079 YYASDVWSFGVTLYELLT 1096 +D+WS GV Y LL+ Sbjct 472 SDKTDMWSLGVITYMLLS 489 Score = 35.4 bits (80), Expect = 3.7, Method: Compositional matrix adjust. Identities = 38/172 (22%), Positives = 70/172 (41%), Gaps = 27/172 (16%) Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 V+K P ++ + E +M+Q++H +L ++ E ++ EY+E G L + Sbjct 327 VIKKQTPKDKEMVMLEIE---VMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERI 383 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL----------LARLGLAE 749 E H+ MV +Q+ + ++ ++H ++ NIL + GLA Sbjct 384 VDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLAR 443 Query 750 GTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 +P KL V G +L+PE + + +S D W G Sbjct 444 RYNPNEKLK---VNFGTPE---------FLSPEVV--NYDQISDKTDMWSLG 481 >sp|P34099|KAPC_DICDI cAMP-dependent protein kinase catalytic subunit OS=Dictyostelium discoideum OX=44689 GN=pkaC PE=1 SV=2 Length=648 Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 65/203 (32%), Positives = 99/203 (49%), Gaps = 17/203 (8%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTL 954 K+IR +G G FGKV Y T DG A+K L Q + E IL ++ Sbjct 336 FKQIRVIGTGTFGKV--YLIQNTKDGC--YYAMKCLNKAYVVQLKQVEHLNSEKSILSSI 391 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL--LFAQQICEGMA 1012 +H I+ +D EK L L+ EYV G + +L R S+ + +A +I + Sbjct 392 HHPFIVNLYQAFQD--EKKLYLLFEYVAGGEVFTHL-RKSMKFSNSTAKFYAAEIVLALE 448 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 +LH Q+ ++RDL N+L+DN +KI DFG AK V + R +P + APE Sbjct 449 FLHKQNIVYRDLKPENLLIDNQGHIKITDFGFAKRVED-----RTFTLCGTPEYL-APEI 502 Query 1073 LKEYKFYYASDVWSFGVTLYELL 1095 ++ A D W+ G+ ++E+L Sbjct 503 IQSKGHGKAVDWWALGILIFEML 525 Score = 38.5 bits (88), Expect = 0.40, Method: Compositional matrix adjust. Identities = 34/150 (23%), Positives = 64/150 (43%), Gaps = 11/150 (7%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S++S + H + ++ + ++ EYV G + LR+ K A+ + Sbjct 386 SILSSIHHPFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAE-IV 444 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-W 778 AL +L +N+V+ ++ N+L+ G IK++D G R + P + Sbjct 445 LALEFLHKQNIVYRDLKPENLLIDNQG-------HIKITDFGFAKRVEDRTFTLCGTPEY 497 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEIC 808 LAPE + + A+D W G + E+ Sbjct 498 LAPEIIQSKGH--GKAVDWWALGILIFEML 525 >sp|P45894|AAPK1_CAEEL 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Caenorhabditis elegans OX=6239 GN=aak-1 PE=2 SV=2 Length=589 Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 75/228 (33%), Positives = 111/228 (49%), Gaps = 25/228 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK----ADCGPQHRSGWKQEIDILRTLYHEH 958 +G+G FG V T+ TG VA+K L G +++ + EID L+ L H H Sbjct 30 IGKGAFGAVK----RGTHIQTGYDVAIKILNRGRMKGLGTVNKT--RNEIDNLQKLTHPH 83 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQ 1017 I + + + LVME V G L Y+ R ++ + + + QQI G++Y H Sbjct 84 ITRLFRVISTPSD--IFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNH 141 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL N+LLD ++ +KI DFGL+ + +G + SP + APE + K Sbjct 142 MIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGD---LLSTACGSP-NYAAPELISN-K 196 Query 1078 FYYA--SDVWSFGVTLYELL--THCDSSQSPPTKFLELIGIAQGQMTV 1121 Y D+WS GV LY +L T Q+ PT F + I G+ TV Sbjct 197 LYVGPEVDLWSCGVILYAMLCGTLPFDDQNVPTLFAK---IKSGRYTV 241 Score = 40.4 bits (93), Expect = 0.11, Method: Compositional matrix adjust. Identities = 46/212 (22%), Positives = 84/212 (40%), Gaps = 24/212 (11%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA 721 + +++H H+ + V + +V E V G L ++ R +G +P+ QQ+ S Sbjct 76 LQKLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITR-KGALPIRESRRYFQQIISG 134 Query 722 LSYLENKNLVHGNV--------CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 +SY N +VH ++ +NI +A GL+ + LS G + E + Sbjct 135 VSYCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYMTDGDLLS-TACGSPNYAAPELI 193 Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHR 832 ++ PE +D W G L + G P ++ P+ ++ Sbjct 194 SNKLYVGPE------------VDLWSCGVILYAMLC-GTLPFDDQNVPTLFAKIKSGRYT 240 Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 +P Q A L S L +P +R + I+ Sbjct 241 VPYSMEKQAADLISTMLQVDPVKRADVKRIVN 272 >sp|O65479|CRK20_ARATH Putative cysteine-rich receptor-like protein kinase 20 OS=Arabidopsis thaliana OX=3702 GN=CRK20 PE=2 SV=2 Length=666 Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 86/289 (30%), Positives = 129/289 (45%), Gaps = 34/289 (12%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I LG+G FG+V + +G VAVK L + G Q ++ E+ ++ L H ++ Sbjct 347 INKLGQGGFGEVYKGTFP-----SGVQVAVKRLSKNSG-QGEKEFENEVVVVAKLQHRNL 400 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYL 1014 +K G C + EK L V E+VP SL DY QL I G+ YL Sbjct 401 VKLLGYCLEGEEKIL--VYEFVPNKSL-DYFLFDPTMQGQLDWSRRYKIIGGIARGILYL 457 Query 1015 HAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 H IHRDL A N+LLD D K+ DFG+A+ R + + APE Sbjct 458 HQDSRLTIIHRDLKAGNILLDADMNPKVADFGMARIFGMDQTEANTRRVVGT-YGYMAPE 516 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL-RL------ 1124 KF SDV+SFGV + E+++ +S ++ G +T RL Sbjct 517 YAMYGKFSMKSDVYSFGVLVLEIVSGMKNS-----SLDQMDGSISNLVTYTWRLWSNGSP 571 Query 1125 TELLE--RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +EL++ G+ + C H+ C + +A+ RPT ++ +L T Sbjct 572 SELVDPSFGDNYQTSEITRC--IHIALLCVQEDANDRPTMSAIVQMLTT 618 Score = 43.9 bits (102), Expect = 0.010, Method: Compositional matrix adjust. Identities = 44/182 (24%), Positives = 83/182 (46%), Gaps = 20/182 (11%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 ++V +K L + F +++++ H +L + G C+ G E I+V E+V + LD Sbjct 367 VQVAVKRLSKNSGQGEKEFENEVVVVAKLQHRNLVKLLGYCLEGEEKILVYEFVPNKSLD 426 Query 697 VWLR--RERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGT 751 +L +G + + + + +A + YL + ++H ++ NIL L Sbjct 427 YFLFDPTMQGQLDWSRRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNIL-----LDADM 481 Query 752 SPFIKLSDPGVG--LGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLL 805 +P K++D G+ G E R+ ++APE G S+ + D + FG +L Sbjct 482 NP--KVADFGMARIFGMDQTEANTRRVVGTYGYMAPEYAMYGKFSMKS--DVYSFGVLVL 537 Query 806 EI 807 EI Sbjct 538 EI 539 >sp|Q8N4C8|MINK1_HUMAN Misshapen-like kinase 1 OS=Homo sapiens OX=9606 GN=MINK1 PE=1 SV=2 Length=1332 Score = 83.6 bits (205), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 62/206 (30%), Positives = 101/206 (49%), Gaps = 24/206 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961 +G G +G+V Y + TG++ A+K + D KQEI++L+ +H +I Sbjct 31 VGNGTYGQV----YKGRHVKTGQLAAIKVM--DVTEDEEEEIKQEINMLKKYSHHRNIAT 84 Query 962 YKGCCEDQ----GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ----LLLFAQQICEGMAY 1013 Y G + + L LVME+ GS+ D L +++ G A + ++I G+A+ Sbjct 85 YYGAFIKKSPPGNDDQLWLVMEFCGAGSVTD-LVKNTKGNALKEDCIAYICREILRGLAH 143 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 LHA IHRD+ +NVLL + VK+ DFG++ + R +W APE + Sbjct 144 LHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---DRTVGRRNTFIGTPYWMAPEVI 200 Query 1074 K-----EYKFYYASDVWSFGVTLYEL 1094 + + Y SD+WS G+T E+ Sbjct 201 ACDENPDATYDYRSDIWSLGITAIEM 226 Score = 36.6 bits (83), Expect = 1.8, Method: Compositional matrix adjust. Identities = 42/191 (22%), Positives = 80/191 (42%), Gaps = 22/191 (12%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG--PENI----MVTEYVEH 692 +KV+D + + E L H ++A +G ++ P N +V E+ Sbjct 51 AAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGA 110 Query 693 GPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G + ++ +G+ + + +++ L++L ++H ++ G+N+LL Sbjct 111 GSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTE------- 163 Query 752 SPFIKLSDPGVGLG---ALSREERVERIP-WLAPECLPGGANSLST---AMDKWGFGATL 804 + +KL D GV + R P W+APE + N +T D W G T Sbjct 164 NAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITA 223 Query 805 LEICFDGEAPL 815 +E+ +G PL Sbjct 224 IEMA-EGAPPL 233 >sp|Q03963|E2AK2_MOUSE Interferon-induced, double-stranded RNA-activated protein kinase OS=Mus musculus OX=10090 GN=Eif2ak2 PE=1 SV=2 Length=515 Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 69/253 (27%), Positives = 117/253 (46%), Gaps = 33/253 (13%) Query 878 LTVNPDSPASDPTVFHKRY---LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 + V+PD + R+ + I ++G G FG+V + + G+ A+K +K Sbjct 220 VKVSPDDVQRNKYTLDARFNSDFEDIEEIGLGGFGQV----FKAKHRIDGKRYAIKRVKY 275 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED--------------QGEKSLQLVMEY 980 + + E+ L L H +I++Y C E + L + ME+ Sbjct 276 NT-----EKAEHEVQALAELNHVNIVQYHSCWEGVDYDPEHSMSDTSRYKTRCLFIQMEF 330 Query 981 VPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037 G+L ++ + + A +L +QI G+ Y+H++ IHRDL N+ L ++R + Sbjct 331 CDKGTLEQWMRNRNQSKVDKALILDLYEQIVTGVEYIHSKGLIHRDLKPGNIFLVDERHI 390 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 KIGDFGLA A+ E R R G + + +PE L + D+++ G+ L ELL Sbjct 391 KIGDFGLATAL-ENDGKSRTRRTG--TLQYMSPEQLFLKHYGKEVDIFALGLILAELLHT 447 Query 1098 CDSSQSPPTKFLE 1110 C ++S KF E Sbjct 448 C-FTESEKIKFFE 459 >sp|Q96RR4|KKCC2_HUMAN Calcium/calmodulin-dependent protein kinase kinase 2 OS=Homo sapiens OX=9606 GN=CAMKK2 PE=1 SV=2 Length=588 Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 52/150 (35%), Positives = 77/150 (51%), Gaps = 6/150 (4%) Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ 1005 QEI IL+ L H +++K +D E L +V E V G + + + Q + Q Sbjct 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQ 294 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 + +G+ YLH Q IHRD+ N+L+ D +KI DFG++ +G + G +P Sbjct 295 DLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF-KGSDALLSNTVG-TPA 352 Query 1066 FWYAPECLKEYKFYY---ASDVWSFGVTLY 1092 F APE L E + + A DVW+ GVTLY Sbjct 353 FM-APESLSETRKIFSGKALDVWAMGVTLY 381 >sp|O08815|SLK_RAT STE20-like serine/threonine-protein kinase OS=Rattus norvegicus OX=10116 GN=Slk PE=1 SV=1 Length=1206 Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 61/205 (30%), Positives = 99/205 (48%), Gaps = 23/205 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I +LG+G FGKV Y N T + A K + + + EIDIL + H +I Sbjct 37 IGELGDGAFGKV----YKAQNKETNVLAAAKVIDTKS-EEELEDYMVEIDILASCDHPNI 91 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQ 1017 +K E +L +++E+ G++ + + +Q+ + +Q E + YLH Sbjct 92 VKLLDAF--YYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDN 149 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---FWYAPECL- 1073 IHRDL A N+L D +K+ DFG++ + R + DS + +W APE + Sbjct 150 KIIHRDLKAGNILFTLDGDIKLADFGVS------AKNTRTIQRRDSFIGTPYWMAPEVVM 203 Query 1074 ----KEYKFYYASDVWSFGVTLYEL 1094 K+ + Y +DVWS G+TL E+ Sbjct 204 CETSKDRPYDYKADVWSLGITLIEM 228 Score = 40.4 bits (93), Expect = 0.13, Method: Compositional matrix adjust. Identities = 38/132 (29%), Positives = 57/132 (43%), Gaps = 16/132 (12%) Query 685 MVTEYVEHGPLD-VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 ++ E+ G +D V L ER + + VV +Q AL+YL + ++H ++ NIL Sbjct 106 ILIEFCAGGAVDAVMLELERP-LTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFT 164 Query 744 RLGLAEGTSPFIKLSDPGVGLG---ALSREERVERIP-WLAPE---CLPGGANSLSTAMD 796 G IKL+D GV + R + P W+APE C D Sbjct 165 LDG-------DIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKAD 217 Query 797 KWGFGATLLEIC 808 W G TL+E+ Sbjct 218 VWSLGITLIEMA 229 >sp|Q9JM52|MINK1_MOUSE Misshapen-like kinase 1 OS=Mus musculus OX=10090 GN=Mink1 PE=1 SV=3 Length=1308 Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 62/206 (30%), Positives = 101/206 (49%), Gaps = 24/206 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961 +G G +G+V Y + TG++ A+K + D KQEI++L+ +H +I Sbjct 31 VGNGTYGQV----YKGRHVKTGQLAAIKVM--DVTEDEEEEIKQEINMLKKYSHHRNIAT 84 Query 962 YKGCCEDQ----GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ----LLLFAQQICEGMAY 1013 Y G + + L LVME+ GS+ D L +++ G A + ++I G+A+ Sbjct 85 YYGAFIKKSPPGNDDQLWLVMEFCGAGSVTD-LVKNTKGNALKEDCIAYICREILRGLAH 143 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 LHA IHRD+ +NVLL + VK+ DFG++ + R +W APE + Sbjct 144 LHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---DRTVGRRNTFIGTPYWMAPEVI 200 Query 1074 K-----EYKFYYASDVWSFGVTLYEL 1094 + + Y SD+WS G+T E+ Sbjct 201 ACDENPDATYDYRSDIWSLGITAIEM 226 Score = 37.0 bits (84), Expect = 1.5, Method: Compositional matrix adjust. Identities = 42/191 (22%), Positives = 80/191 (42%), Gaps = 22/191 (12%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG--PENI----MVTEYVEH 692 +KV+D + + E L H ++A +G ++ P N +V E+ Sbjct 51 AAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGA 110 Query 693 GPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G + ++ +G+ + + +++ L++L ++H ++ G+N+LL Sbjct 111 GSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTE------- 163 Query 752 SPFIKLSDPGVGLG---ALSREERVERIP-WLAPECLPGGANSLST---AMDKWGFGATL 804 + +KL D GV + R P W+APE + N +T D W G T Sbjct 164 NAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITA 223 Query 805 LEICFDGEAPL 815 +E+ +G PL Sbjct 224 IEMA-EGAPPL 233 >sp|O80888|M3K17_ARATH Mitogen-activated protein kinase kinase kinase 17 OS=Arabidopsis thaliana OX=3702 GN=MAPKKK17 PE=1 SV=1 Length=372 Score = 80.9 bits (198), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 65/215 (30%), Positives = 101/215 (47%), Gaps = 33/215 (15%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ-EIDILRTLYHEHI 959 R LG G V Y + E++AVK+ + HRS + Q E IL +L ++ Sbjct 7 RILGRGSTATV----YAAAGHNSDEILAVKSSEV-----HRSEFLQREAKILSSLSSPYV 57 Query 960 IKYKGC---CEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYL 1014 I Y+G E G L+MEY P G+L D + + +++ + + I +G+ Y+ Sbjct 58 IGYRGSETKRESNGVVMYNLLMEYAPYGTLTDAAAKDGGRVDETRVVKYTRDILKGLEYI 117 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF----WYAP 1070 H++ +H D+ NV++ KI DFG AK RV +SPV + AP Sbjct 118 HSKGIVHCDVKGSNVVISEKGEAKIADFGCAK---------RVDPVFESPVMGTPAFMAP 168 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 E + K SD+W+ G T+ E++T SPP Sbjct 169 EVARGEKQGKESDIWAVGCTMIEMVTG-----SPP 198 Score = 37.0 bits (84), Expect = 0.95, Method: Compositional matrix adjust. Identities = 48/216 (22%), Positives = 82/216 (38%), Gaps = 32/216 (15%) Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVT-----EYVEHGPLDVWLRRERGHVPMAWKMV 713 A ++S +S ++ G + N +V EY +G L ++ G V + Sbjct 46 AKILSSLSSPYVIGYRGSETKRESNGVVMYNLLMEYAPYGTLTDAAAKDGGRVDETRVVK 105 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 + + L Y+ +K +VH +V G N++++ G A K++D G R + V Sbjct 106 YTRDILKGLEYIHSKGIVHCDVKGSNVVISEKGEA-------KIAD----FGCAKRVDPV 154 Query 774 ERIP------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--EH 825 P ++APE G + D W G T++E+ G P E Sbjct 155 FESPVMGTPAFMAPEVARGEKQGKES--DIWAVGCTMIEM-VTGSPPWTKADSREDPVSV 211 Query 826 FYQRQHRLPEPSCPQL-----ATLTSQCLTYEPTQR 856 Y+ + P P L +CL E +R Sbjct 212 LYRVGYSSETPELPCLLAEEAKDFLEKCLKREANER 247 >sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo sapiens OX=9606 GN=GSK3A PE=1 SV=2 Length=483 Score = 82.0 bits (201), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 70/211 (33%), Positives = 104/211 (49%), Gaps = 33/211 (16%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I+ +G G FG V Y T E+VA+K + D ++R E+ I+R L H +I Sbjct 122 IKVIGNGSFGVV----YQARLAETRELVAIKKVLQDKRFKNR-----ELQIMRKLDHCNI 172 Query 960 IKYKGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRH------SIGLAQLLLFAQQICE 1009 ++ + GEK L LV+EYVP R + RH +I + + ++ Q+ Sbjct 173 VRLRYFFYSSGEKKDELYLNLVLEYVPETVYR--VARHFTKAKLTIPILYVKVYMYQLFR 230 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGH---EYYRVREDGDSPV 1065 +AY+H+Q HRD+ +N+L+D D V K+ DFG AK + G Y R Sbjct 231 SLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR------- 283 Query 1066 FWYAPECLKEYKFYYAS-DVWSFGVTLYELL 1095 ++ APE + Y +S DVWS G L ELL Sbjct 284 YYRAPELIFGATDYTSSIDVWSAGCVLAELL 314 Score = 36.6 bits (83), Expect = 1.4, Method: Compositional matrix adjust. Identities = 31/128 (24%), Positives = 59/128 (46%), Gaps = 12/128 (9%) Query 685 MVTEYVEHGPLDVW--LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +V EYV V + + +P+ + V QL +L+Y+ ++ + H ++ +N+L+ Sbjct 193 LVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLV 252 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWG 799 + + +KL D G + E V I + APE + GA ++++D W Sbjct 253 ------DPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELI-FGATDYTSSIDVWS 305 Query 800 FGATLLEI 807 G L E+ Sbjct 306 AGCVLAEL 313 >sp|Q9TXJ0|CMK1_CAEEL Calcium/calmodulin-dependent protein kinase type 1 OS=Caenorhabditis elegans OX=6239 GN=cmk-1 PE=1 SV=1 Length=348 Score = 80.5 bits (197), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 65/215 (30%), Positives = 97/215 (45%), Gaps = 16/215 (7%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 PA + T+ K + + LG G F KV L + G+M AVK + Sbjct 12 PAPNATIREKYDFRDV--LGTGAFSKVFLA---ESKSDAGQMYAVKCIDKKALKGKEESL 66 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLF 1003 + EI +LR L H +I++ +++ + + LVME V G L D + + S Sbjct 67 ENEIKVLRKLRHNNIVQLFDTYDEK--QFVYLVMELVTGGELFDRIVAKGSYTEQDASNL 124 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 +Q+ E + ++H +HRDL N+L D D + I DFGL+K G V Sbjct 125 IRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKTEDSG-----VMAT 179 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 + APE L++ + A DVWS GV Y LL Sbjct 180 ACGTPGYVAPEVLQQKPYGKAVDVWSIGVIAYILL 214 >sp|P24100|CDKA1_ARATH Cyclin-dependent kinase A-1 OS=Arabidopsis thaliana OX=3702 GN=CDKA-1 PE=1 SV=1 Length=294 Score = 79.7 bits (195), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 63/208 (30%), Positives = 102/208 (49%), Gaps = 20/208 (10%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYH 956 +K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ + H Sbjct 5 EKVEKIGEGTYGVV----YKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR--DYLPRHSIGLAQLLLFAQQICEGMAYL 1014 +I+K + EK L LV EY+ L + D P S L + + QI G+AY Sbjct 61 SNIVKLQDVV--HSEKRLYLVFEYLDLDLKKHMDSTPDFSKDLHMIKTYLYQILRGIAYC 118 Query 1015 HAQHYIHRDLAARNVLLD-NDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070 H+ +HRDL +N+L+D +K+ DFGLA+A +P + V WY AP Sbjct 119 HSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEV------VTLWYRAP 172 Query 1071 EC-LKEYKFYYASDVWSFGVTLYELLTH 1097 E L + + D+WS G E+++ Sbjct 173 EILLGSHHYSTPVDIWSVGCIFAEMISQ 200 >sp|Q9SYA0|Y1150_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61500 OS=Arabidopsis thaliana OX=3702 GN=At1g61500 PE=2 SV=2 Length=804 Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 83/284 (29%), Positives = 130/284 (46%), Gaps = 25/284 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V G+ +AVK L + G Q + + EI ++ L H ++++ Sbjct 497 LGQGGFGSVY-----KGKLQDGKEIAVKRLSSSSG-QGKEEFMNEIVLISKLQHRNLVRV 550 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017 GCC ++ EK L+ E++ SL +L R I + Q I G+ YLH Sbjct 551 LGCCIEEEEK--LLIYEFMVNKSLDTFLFDSRKRLEIDWPKRFDIIQGIARGLLYLHHDS 608 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 IHRDL N+LLD KI DFGLA+ + +G EY + + +PE Sbjct 609 RLRVIHRDLKVSNILLDEKMNPKISDFGLAR-MYQGTEYQDNTRRVVGTLGYMSPEYAWT 667 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 F SD++SFGV + E+++ S+ S + LI A + R +LL++ Sbjct 668 GMFSEKSDIYSFGVLMLEIISGEKISRFSYGVEGKTLIAYAWESWSEYRGIDLLDQ---- 723 Query 1135 PRPDKC-PCEVYHLMKN---CWETEASFRPTFENLIPILKTVHE 1174 D C P EV ++ C + + + RP L+ +L T + Sbjct 724 DLADSCHPLEVGRCIQIGLLCVQHQPADRPNTLELLAMLTTTSD 767 >sp|Q38868|CDPK9_ARATH Calcium-dependent protein kinase 9 OS=Arabidopsis thaliana OX=3702 GN=CPK9 PE=1 SV=1 Length=541 Score = 82.0 bits (201), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 67/209 (32%), Positives = 104/209 (50%), Gaps = 30/209 (14%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHE- 957 ++LG G FG V+ C T + TG+ A K++ K + ++EI I++ L + Sbjct 95 KELGRGQFG-VTYLC---TENSTGKKYACKSISKKKLVTKADKDDMRREIQIMQHLSGQP 150 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-------YLPRHSIGLAQLLLFAQQICEG 1010 +I+++KG ED EK++ LVME G L D Y R + + + ++ +IC Sbjct 151 NIVEFKGAYED--EKAVNLVMELCAGGELFDRIIAKGHYTERAAASVCRQIVNVVKICHF 208 Query 1011 MAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 M LH RDL N LL D L+K DFGL+ + EG +V D ++ Sbjct 209 MGVLH------RDLKPENFLLSSKDEKALIKATDFGLSVFIEEG----KVYRDIVGSAYY 258 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096 APE L+ ++ D+WS G+ LY LL+ Sbjct 259 VAPEVLRR-RYGKEVDIWSAGIILYILLS 286 >sp|Q91ZN7|CHK1_RAT Serine/threonine-protein kinase Chk1 OS=Rattus norvegicus OX=10116 GN=Chek1 PE=2 SV=1 Length=476 Score = 81.6 bits (200), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 67/199 (34%), Positives = 97/199 (49%), Gaps = 11/199 (6%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 ++ LGEG +G+V L N T E VAVK + K+EI I + L HE++ Sbjct 12 VQTLGEGAYGEVQL----AVNRITEEAVAVKIVDMKRAIDCPENIKKEICINKMLNHENV 67 Query 960 IKYKGCCEDQGEKSLQ-LVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +K+ G + E ++Q L +EY G L D + P + F Q+ G+ YLH Sbjct 68 VKFYG---HRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVYLHGI 124 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 HRD+ N+LLD +KI DFGLA V + R+ + + APE LK + Sbjct 125 GITHRDIKPENLLLDERDNLKISDFGLA-TVFRHNNRERLLNKMCGTLPYVAPELLKRKE 183 Query 1078 FYYA-SDVWSFGVTLYELL 1095 F+ DVWS G+ L +L Sbjct 184 FHAEPVDVWSCGIVLTAML 202 >sp|Q8BRK8|AAPK2_MOUSE 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Mus musculus OX=10090 GN=Prkaa2 PE=1 SV=3 Length=552 Score = 82.0 bits (201), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 73/201 (36%), Positives = 95/201 (47%), Gaps = 22/201 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957 LG G FGKV + + TG VAVK L + RS K+EI L+ H Sbjct 22 LGVGTFGKVKI----GEHQLTGHKVAVKILNRQ---KIRSLDVVGKIKREIQNLKLFRHP 74 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016 HIIK + +VMEYV G L DY+ +H + + QQI + Y H Sbjct 75 HIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHR 132 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE + Sbjct 133 HMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 187 Query 1077 KFYYA--SDVWSFGVTLYELL 1095 + Y D+WS GV LY LL Sbjct 188 RLYAGPEVDIWSCGVILYALL 208 Score = 35.4 bits (80), Expect = 4.1, Method: Compositional matrix adjust. Identities = 62/262 (24%), Positives = 105/262 (40%), Gaps = 24/262 (9%) Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726 H H+ ++ V + MV EYV G L ++ + G V + QQ+ SA+ Y Sbjct 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKH-GRVEEVEARRLFQQILSAVDYCH 131 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-----WLAP 781 +VH ++ N+LL A K++D GL + + R + AP Sbjct 132 RHMVVHRDLKPENVLLDAQMNA-------KIAD--FGLSNMMSDGEFLRTSCGSPNYAAP 182 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQ 840 E + G + +D W G L + G P P+ + +P+ Sbjct 183 EVISGRLYA-GPEVDIWSCGVILYALLC-GTLPFDDEHVPTLFKKIRGGVFYIPDYLNRS 240 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 +ATL L +P +R + + I R+ + +L L P+ P+ D V +K++ Sbjct 241 VATLLMHMLQVDPLKRATIKDI-REHEWFK-QDLPSYLF--PEDPSYDANVIDDEAVKEV 296 Query 901 RDLGEGHFGKV--SLYCYDPTN 920 + E +V SLY DP + Sbjct 297 CEKFECTESEVMNSLYSGDPQD 318 >sp|O54988|SLK_MOUSE STE20-like serine/threonine-protein kinase OS=Mus musculus OX=10090 GN=Slk PE=1 SV=2 Length=1233 Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 61/205 (30%), Positives = 99/205 (48%), Gaps = 23/205 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I +LG+G FGKV Y N T + A K + + + EIDIL + H +I Sbjct 37 IGELGDGAFGKV----YKAQNKETNVLAAAKVIDTK-SEEELEDYMVEIDILASCDHPNI 91 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQ 1017 +K E +L +++E+ G++ + + +Q+ + +Q E + YLH Sbjct 92 VKLLDAF--YYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDN 149 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---FWYAPECL- 1073 IHRDL A N+L D +K+ DFG++ + R + DS + +W APE + Sbjct 150 KIIHRDLKAGNILFTLDGDIKLADFGVS------AKNTRTIQRRDSFIGTPYWMAPEVVM 203 Query 1074 ----KEYKFYYASDVWSFGVTLYEL 1094 K+ + Y +DVWS G+TL E+ Sbjct 204 CETSKDRPYDYKADVWSLGITLIEM 228 Score = 40.4 bits (93), Expect = 0.13, Method: Compositional matrix adjust. Identities = 31/104 (30%), Positives = 44/104 (42%), Gaps = 14/104 (13%) Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG---ALS 768 VV +Q AL+YL + ++H ++ NIL G IKL+D GV + Sbjct 133 QVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDG-------DIKLADFGVSAKNTRTIQ 185 Query 769 REERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808 R + P W+APE C D W G TL+E+ Sbjct 186 RRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMA 229 >sp|D7UPN3|RLK10_ORYSJ LysM domain receptor-like kinase 10 OS=Oryza sativa subsp. japonica OX=39947 GN=RLK10 PE=2 SV=1 Length=605 Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 80/286 (28%), Positives = 124/286 (43%), Gaps = 33/286 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FG V + GE A+K + G Q + E+ +L ++H ++++ Sbjct 323 IGQGGFGSVYY------AELRGEKTAIKKM----GMQATQEFLAELKVLTHVHHLNLVRL 372 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH- 1018 G C E L LV E++ G+L +L R + A + A G+ YLH +H Sbjct 373 IGYCV---ENCLFLVYEFIDNGNLSQHLQRTGYAPLSWATRVQIALDSARGLEYLH-EHV 428 Query 1019 ---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG--HEYYRVREDGDSPVFWYAPECL 1073 Y+HRD+ + N+LLD D KI DFGLAK G + R G F Y P Sbjct 429 VPVYVHRDIKSANILLDKDFRAKIADFGLAKLTEVGSMSQSLSTRVAG---TFGYMPPEA 485 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR-------LTE 1126 + + DV++FGV LYELL+ + E G+ L L E Sbjct 486 RYGEVSPKVDVYAFGVVLYELLSAKQAIVRSSESVSESKGLVFLFEEALSAPNPTEALDE 545 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 L++ + P ++ L K+C E RPT +++ L + Sbjct 546 LIDPSLQGDYPVDSALKIASLAKSCTHEEPGMRPTMRSVVVALMAL 591 >sp|Q09137|AAPK2_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Rattus norvegicus OX=10116 GN=Prkaa2 PE=1 SV=1 Length=552 Score = 82.0 bits (201), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 73/201 (36%), Positives = 95/201 (47%), Gaps = 22/201 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957 LG G FGKV + + TG VAVK L + RS K+EI L+ H Sbjct 22 LGVGTFGKVKI----GEHQLTGHKVAVKILNRQ---KIRSLDVVGKIKREIQNLKLFRHP 74 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016 HIIK + +VMEYV G L DY+ +H + + QQI + Y H Sbjct 75 HIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHR 132 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE + Sbjct 133 HMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 187 Query 1077 KFYYA--SDVWSFGVTLYELL 1095 + Y D+WS GV LY LL Sbjct 188 RLYAGPEVDIWSCGVILYALL 208 Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust. Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 24/262 (9%) Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726 H H+ ++ V + MV EYV G L ++ + G V + QQ+ SA+ Y Sbjct 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKH-GRVEEVEARRLFQQILSAVDYCH 131 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-----WLAP 781 +VH ++ N+LL A K++D GL + + R + AP Sbjct 132 RHMVVHRDLKPENVLLDAQMNA-------KIAD--FGLSNMMSDGEFLRTSCGSPNYAAP 182 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQ 840 E + G + +D W G L + G P P+ + +PE Sbjct 183 EVISGRLYA-GPEVDIWSCGVILYALLC-GTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS 240 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 +ATL L +P +R + + I R+ + +L L P+ P+ D V +K++ Sbjct 241 IATLLMHMLQVDPLKRATIKDI-REHEWFK-QDLPSYLF--PEDPSYDANVIDDEAVKEV 296 Query 901 RDLGEGHFGKV--SLYCYDPTN 920 + E +V SLY DP + Sbjct 297 CEKFECTESEVMNSLYSGDPQD 318 >sp|Q8RWZ5|SD25_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase SD2-5 OS=Arabidopsis thaliana OX=3702 GN=SD25 PE=1 SV=1 Length=821 Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 79/297 (27%), Positives = 136/297 (46%), Gaps = 55/297 (19%) Query 903 LGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG V +GT G +AVK L+ Q + ++ E+ I+ +++H H+ Sbjct 499 LGQGGFGSVY--------EGTLPDGSRLAVKKLEGI--GQGKKEFRAEVSIIGSIHHLHL 548 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYL 1014 ++ +G C + + L E++ GSL ++ R G L A +G+AYL Sbjct 549 VRLRGFCAEGAHR--LLAYEFLSKGSLERWIFRKKDGDVLLDWDTRFNIALGTAKGLAYL 606 Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP--EGHEYYRVREDGDSPVFWYA 1069 H +H D+ N+LLD++ K+ DFGLAK + + H + +R + A Sbjct 607 HEDCDARIVHCDIKPENILLDDNFNAKVSDFGLAKLMTREQSHVFTTMR----GTRGYLA 662 Query 1070 PECLKEYKFYYASDVWSFGVTLYELL---THCDSSQS------PPTKFL-----ELIGIA 1115 PE + Y SDV+S+G+ L EL+ + D S++ P F +L+ I Sbjct 663 PEWITNYAISEKSDVYSYGMVLLELIGGRKNYDPSETSEKCHFPSFAFKKMEEGKLMDIV 722 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 G+M + +T+ ER+ R K C + + RP+ ++ +L+ V Sbjct 723 DGKMKNVDVTD-----ERVQRAMKTALW-------CIQEDMQTRPSMSKVVQMLEGV 767 Score = 55.5 bits (132), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 53/185 (29%), Positives = 84/185 (45%), Gaps = 25/185 (14%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL-RRERGHVPMAW--K 711 F S++ + H HL + G C G ++ E++ G L+ W+ R++ G V + W + Sbjct 533 FRAEVSIIGSIHHLHLVRLRGFCAEGAHRLLAYEFLSKGSLERWIFRKKDGDVLLDWDTR 592 Query 712 MVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 +A A L+YL + +VH ++ NILL A K+SD G+ ++ Sbjct 593 FNIALGTAKGLAYLHEDCDARIVHCDIKPENILLDDNFNA-------KVSDFGLA-KLMT 644 Query 769 REE-------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 RE+ R R +LAPE + A +S D + +G LLE+ G S Sbjct 645 REQSHVFTTMRGTR-GYLAPEWITNYA--ISEKSDVYSYGMVLLEL-IGGRKNYDPSETS 700 Query 822 EKEHF 826 EK HF Sbjct 701 EKCHF 705 >sp|C0LGP2|MEE39_ARATH Probable LRR receptor-like serine/threonine-protein kinase MEE39 OS=Arabidopsis thaliana OX=3702 GN=MEE39 PE=1 SV=1 Length=878 Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 63/204 (31%), Positives = 102/204 (50%), Gaps = 15/204 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LGEG FG V Y +G+ E VAVK L + Q +K E+++L ++H +++ Sbjct 570 RPLGEGGFGVV----YHGDLNGS-EQVAVKLL-SQTSAQGYKEFKAEVELLLRVHHINLV 623 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHS---IGLAQLLLFAQQICEGMAYLHA 1016 G C++Q L+ EY+ G L +L +H + L A + G+ YLH Sbjct 624 NLVGYCDEQDH--FALIYEYMSNGDLHQHLSGKHGGSVLNWGTRLQIAIEAALGLEYLHT 681 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +HRD+ + N+LLD + KI DFGL+++ G + +V + + PE Sbjct 682 GCKPAMVHRDVKSTNILLDEEFKAKIADFGLSRSFQVGGDQSQVSTVVAGTLGYLDPEYY 741 Query 1074 KEYKFYYASDVWSFGVTLYELLTH 1097 + SDV+SFG+ L E++T+ Sbjct 742 LTSELSEKSDVYSFGILLLEIITN 765 Score = 38.1 bits (87), Expect = 0.62, Method: Compositional matrix adjust. Identities = 53/201 (26%), Positives = 83/201 (41%), Gaps = 22/201 (11%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G G E +V +K+L + F L+ +V H +L + G C ++ EY Sbjct 583 GDLNGSE-QVAVKLLSQTSAQGYKEFKAEVELLLRVHHINLVNLVGYCDEQDHFALIYEY 641 Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744 + +G L L + G + W ++ +A + A L YL +VH +V NILL Sbjct 642 MSNGDLHQHLSGKHGGSVLNWGTRLQIAIEAALGLEYLHTGCKPAMVHRDVKSTNILLDE 701 Query 745 LGLAEGTSPFIKLSDPGVGL-----GALSREERVE--RIPWLAPECLPGGANSLSTAMDK 797 A K++D G+ G S+ V + +L PE + LS D Sbjct 702 EFKA-------KIADFGLSRSFQVGGDQSQVSTVVAGTLGYLDPEYYL--TSELSEKSDV 752 Query 798 WGFGATLLEICFDGEAPLQSR 818 + FG LLEI + Q+R Sbjct 753 YSFGILLLEIITNQRVIDQTR 773 >sp|Q8RXC8|RBK2_ARATH Receptor-like cytosolic serine/threonine-protein kinase RBK2 OS=Arabidopsis thaliana OX=3702 GN=RBK2 PE=1 SV=1 Length=460 Score = 81.6 bits (200), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 56/179 (31%), Positives = 92/179 (51%), Gaps = 10/179 (6%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 G+++AVK L + + + E+ I+ + H + K+ GCC + G + LV PL Sbjct 165 GKLIAVKRLTKGTPDEQTAEFLSELGIIAHVDHPNTAKFIGCCIEGG---MHLVFRLSPL 221 Query 984 GSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLV 1037 GSL L ++ + ++ A +G+ YLH + IHRD+ A N+LL D Sbjct 222 GSLGSLLHGPSKYKLTWSRRYNVALGTADGLVYLHEGCQRRIIHRDIKADNILLTEDFQP 281 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 +I DFGLAK +P+ ++ V + + ++APE +DV++FGV L EL+T Sbjct 282 QICDFGLAKWLPKQLTHHNVSK-FEGTFGYFAPEYFMHGIVDEKTDVFAFGVLLLELIT 339 >sp|Q8S8S7|PUB34_ARATH U-box domain-containing protein 34 OS=Arabidopsis thaliana OX=3702 GN=PUB34 PE=3 SV=1 Length=801 Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 82/291 (28%), Positives = 138/291 (47%), Gaps = 35/291 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG +GKV Y + D T AVK ++ D P+ + + +E+++L L H H++ Sbjct 448 IGEGGYGKV----YQCSLDSTP--AAVKVVRLDT-PEKKQEFLKEVEVLSQLRHPHVVLL 500 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ-----QICEGMAYLHAQ 1017 G C + G LV EY+ GSL +Y+ H L F + ++ G+A+LH+ Sbjct 501 LGACPENG----CLVYEYLENGSLEEYI-FHRKNKPPLPWFIRFRVIFEVACGLAFLHSS 555 Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAV----PEGHEYYRVREDGDSPVFWYAP 1070 +HRDL N+LL+ + + KI D GLAK V P+ YR + + + P Sbjct 556 KPEPIVHRDLKPGNILLNRNYVSKIADVGLAKLVTDVAPDNVTMYRNSVLAGT-LHYIDP 614 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E + SD+++FG+ + +LLT + P+ + + A + T LTE+L++ Sbjct 615 EYHRTGTIRPKSDLYAFGIIILQLLTARN-----PSGIVPAVENAVKKGT---LTEMLDK 666 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN-LIPILKTVHEKYQGQA 1180 P E+ + C E RP ++ +IP+LK + E + Sbjct 667 SV-TDWPLAETEELARIGLKCAEFRCRDRPDLKSEVIPVLKRLVETANSKV 716 Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 45/183 (25%), Positives = 83/183 (45%), Gaps = 35/183 (19%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHVPMAW--K 711 F + ++SQ+ H H+ + G C PEN +V EY+E+G L+ ++ + P+ W + Sbjct 482 FLKEVEVLSQLRHPHVVLLLGAC---PENGCLVYEYLENGSLEEYIFHRKNKPPLPWFIR 538 Query 712 MVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 V ++A L++L + +VH ++ NILL R ++ K++D VGL L Sbjct 539 FRVIFEVACGLAFLHSSKPEPIVHRDLKPGNILLNRNYVS-------KIAD--VGLAKLV 589 Query 769 REERVERIPWLAPECLPGG----------ANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + + + L G ++ D + FG +L++ L +R Sbjct 590 TDVAPDNVTMYRNSVLAGTLHYIDPEYHRTGTIRPKSDLYAFGIIILQL-------LTAR 642 Query 819 SPS 821 +PS Sbjct 643 NPS 645 >sp|P20689|MYLK2_RAT Myosin light chain kinase 2, skeletal/cardiac muscle OS=Rattus norvegicus OX=10116 GN=Mylk2 PE=1 SV=2 Length=610 Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 61/198 (31%), Positives = 99/198 (50%), Gaps = 15/198 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V C T TG +A K +K P+ + EI+++ L H ++I+ Sbjct 305 LGGGKFGAV-CTC---TERSTGLKLAAKVIKKQT-PKDKEMVLLEIEVMNQLNHRNLIQL 359 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020 E E + L MEY+ G L + + L ++ ++F +QIC+G+ ++H + Sbjct 360 YSAIETSHE--IILFMEYIEGGELFERIVDEDYQLTEVDTMVFVRQICDGILFMHKMRVL 417 Query 1021 HRDLAARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 H DL N+L N LVKI DFGLA+ + +++ + +P F +PE + + Sbjct 418 HLDLKPENILCVNTTGHLVKIIDFGLARRY---NPNEKLKVNFGTPEF-LSPEVVNYDQI 473 Query 1079 YYASDVWSFGVTLYELLT 1096 +D+WS GV Y LL+ Sbjct 474 SDKTDMWSLGVITYMLLS 491 Score = 35.4 bits (80), Expect = 3.4, Method: Compositional matrix adjust. Identities = 39/180 (22%), Positives = 74/180 (41%), Gaps = 24/180 (13%) Query 632 DRGQELRVVLKVLD---PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 +R L++ KV+ P ++ L E +M+Q++H +L ++ E I+ E Sbjct 318 ERSTGLKLAAKVIKKQTPKDKEMVLLEIE---VMNQLNHRNLIQLYSAIETSHEIILFME 374 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 Y+E G L + E + MV +Q+ + ++ ++H ++ NIL Sbjct 375 YIEGGELFERIVDEDYQLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNT--- 431 Query 749 EGTSPFIKLSDPGVGLGALSREERVERIP-------WLAPECLPGGANSLSTAMDKWGFG 801 T +K+ D G R E++ +L+PE + + +S D W G Sbjct 432 --TGHLVKIID----FGLARRYNPNEKLKVNFGTPEFLSPEVV--NYDQISDKTDMWSLG 483 >sp|O70405|ULK1_MOUSE Serine/threonine-protein kinase ULK1 OS=Mus musculus OX=10090 GN=Ulk1 PE=1 SV=1 Length=1051 Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 60/180 (33%), Positives = 87/180 (48%), Gaps = 16/180 (9%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VAVK + + ++ +EI IL+ L HE+I+ E S+ LVMEY G L Sbjct 43 VAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEM--ANSVYLVMEYCNGGDL 100 Query 987 RDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN---------DRL 1036 DYL ++ + LF QQI M LH++ IHRDL +N+LL N + Sbjct 101 ADYLHTMRTLSEDTVRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIR 160 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 VKI DFG A+ + SP++ APE + + +D+WS G +Y+ LT Sbjct 161 VKIADFGFARYL---QSNMMAATLCGSPMYM-APEVIMSQHYDGKADLWSIGTIVYQCLT 216 Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 39/178 (22%), Positives = 76/178 (43%), Gaps = 9/178 (5%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 ++ ++ H ++ ++ +V EY G L +L R ++ + QQ+A Sbjct 66 ILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFL-QQIAG 124 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---- 776 A+ L +K ++H ++ +NILL+ G I++ G + + Sbjct 125 AMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAATLCGS 184 Query 777 -PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833 ++APE + + D W G T++ C G+AP Q+ SP + FY++ L Sbjct 185 PMYMAPEVI--MSQHYDGKADLWSIG-TIVYQCLTGKAPFQASSPQDLRLFYEKNKTL 239 >sp|Q54HC6|ARKA_DICDI Ankyrin repeat-containing protein kinase A OS=Dictyostelium discoideum OX=44689 GN=arkA PE=1 SV=1 Length=1460 Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 71/287 (25%), Positives = 128/287 (45%), Gaps = 23/287 (8%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 L+ +G G GKV Y G +VA+K LK+ R + +E +L +L Sbjct 1112 LEYTEKIGSGASGKVFKGIY------RGRVVAIKVLKSADDEMTREDFLKEFGVLASLES 1165 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016 I+ G E + LVMEY GS+ + ++ + F QQ+ G+ LH Sbjct 1166 HTIVGLYGVVL---EPKICLVMEYCSNGSIYHSIRKNPPSWERFFSFVQQMLAGINALHQ 1222 Query 1017 Q--HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 +HRD+ N L++++ VK+ DFGL++ E ++ + G S + APE + Sbjct 1223 STPQVLHRDIKTLNFLVNHNNKVKVADFGLSRFNTESNQETLNKTRGTS--VYCAPEVFE 1280 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 ++ SD++S G+ ++E++ +C + E ++ L+ +R+ Sbjct 1281 GKEYNERSDMYSMGIVMWEIV-YCVVYGCYMIPYQEY----NKMFNAFQVALLVNSSKRV 1335 Query 1135 PRPDKCPCEVYHLMKN----CWETEASFRPTFENLIPILKTVHEKYQ 1177 RP P V ++K+ W+ + S RPT + L ++Y+ Sbjct 1336 LRP-TIPIGVPQVLKDLIYCLWDHDVSSRPTATEAMTALAVCEKEYK 1381 >sp|Q54G43|SHKE_DICDI Dual specificity protein kinase shkE OS=Dictyostelium discoideum OX=44689 GN=shkE PE=3 SV=1 Length=710 Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 70/267 (26%), Positives = 118/267 (44%), Gaps = 32/267 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G +GKV Y T G V V + + +S +K E++I++ ++H +++ Sbjct 243 LGGGAYGKV----YKATCRGKKVAVKVPKKQTLSESELKS-FKNEVEIMKQIFHPNVVLC 297 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ-HYIH 1021 G C G+ + + L L L + + G+ +LH + IH Sbjct 298 LGACTKPGKVMIVSELMQTDLEKLIHSSEVEPPPLYERMKMCLDAALGINWLHGICNIIH 357 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP---VFWYAPECLKEYKF 1078 RDL N+++ D+ VKIGDFG ++ + G D P + APE + +++F Sbjct 358 RDLKLANLMISKDKTVKIGDFGFSQVIKTG----TTLSDQKGPKGTALYMAPEVMMKHEF 413 Query 1079 YYASDVWSFGVTLYELLTHCDS---SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 +DV+SFG+ LYE+ T C+ S F + I + R P Sbjct 414 NEKADVYSFGLILYEMAT-CEELFPEYSEIDPFYDAI---------------CNKKLRPP 457 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTF 1162 PD P + L++ CW+ + + RP+F Sbjct 458 IPDSFPKSLKTLIQKCWDHDPNKRPSF 484 Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust. Identities = 52/232 (22%), Positives = 105/232 (45%), Gaps = 31/232 (13%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 +F +M Q+ H ++ G C + + ++V+E ++ + E P+ +M Sbjct 278 SFKNEVEIMKQIFHPNVVLCLGACTKPGKVMIVSELMQTDLEKLIHSSEVEPPPLYERMK 337 Query 714 VAQQLASALSYLENKNLVHG--NVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGAL 767 + A +++L HG N+ R++ LA L +++ + +K+ D G + G Sbjct 338 MCLDAALGINWL------HGICNIIHRDLKLANLMISKDKT--VKIGDFGFSQVIKTGTT 389 Query 768 SREERVER--IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP--SEK 823 +++ + ++APE + + + D + FG L E+ A + P SE Sbjct 390 LSDQKGPKGTALYMAPEVM--MKHEFNEKADVYSFGLILYEM-----ATCEELFPEYSEI 442 Query 824 EHFY----QRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + FY ++ R P P S P+ L TL +C ++P +RPSF + + + + Sbjct 443 DPFYDAICNKKLRPPIPDSFPKSLKTLIQKCWDHDPNKRPSFNEVTQRMNEV 494 >sp|Q6BVA0|IPL1_DEBHA Spindle assembly checkpoint kinase OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=IPL1 PE=3 SV=2 Length=412 Score = 81.3 bits (199), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 57/195 (29%), Positives = 88/195 (45%), Gaps = 7/195 (4%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G GKV YC G + V A K + +++EI+I L H I + Sbjct 154 LGKGKLGKV--YCVKHKTSGYIAALKVMAKKDLIDLKLEKNFRREIEIQSNLIHPKISRL 211 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G D K++ L++EY G L +L + A + Q+ + YLH +H IH Sbjct 212 YGFFYDH--KNVYLILEYSIHGELYHHLKVQRRFNDATASHYIYQVALALDYLHTKHIIH 269 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RD+ N+LL D +K+ DFG + R+ G + + PE ++ + Y Sbjct 270 RDIKPENILLSTDNCIKLSDFGWSVKSSPSSSTKRLTICG--TLDYLPPEMIESNEHDYT 327 Query 1082 SDVWSFGVTLYELLT 1096 D+WS G+ YE L Sbjct 328 VDIWSLGILCYEFLV 342 Score = 40.0 bits (92), Expect = 0.13, Method: Compositional matrix adjust. Identities = 49/218 (22%), Positives = 85/218 (39%), Gaps = 23/218 (11%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F + S + H ++ ++G ++ EY HG L L+ +R + Sbjct 193 FRREIEIQSNLIHPKISRLYGFFYDHKNVYLILEYSIHGELYHHLKVQRRFNDATASHYI 252 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-----VGLGALSR 769 Q +A AL YL K+++H ++ NILL+ T IKLSD G + R Sbjct 253 YQ-VALALDYLHTKHIIHRDIKPENILLS-------TDNCIKLSDFGWSVKSSPSSSTKR 304 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 + +L PE + +N +D W G E G+ P + +K Y+R Sbjct 305 LTICGTLDYLPPEMIE--SNEHDYTVDIWSLGILCYEFLV-GKPPFEE---IDKNSTYKR 358 Query 830 ----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 ++P + L + L P +R + ++ Sbjct 359 IAKVDLKIPSFLSSEATDLILRLLQKSPKKRITLAEVM 396 >sp|Q04735|CDK16_MOUSE Cyclin-dependent kinase 16 OS=Mus musculus OX=10090 GN=Cdk16 PE=1 SV=1 Length=496 Score = 81.6 bits (200), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 60/202 (30%), Positives = 94/202 (47%), Gaps = 15/202 (7%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 K+ LGEG + V Y + T +VA+K ++ + +E+ +L+ L H + Sbjct 167 KLDKLGEGTYATV----YKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHAN 222 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHA 1016 I+ EKSL LV EY+ L+ YL + I + + LF Q+ G+AY H Sbjct 223 IVTLHDII--HTEKSLTLVFEYLD-KDLKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHR 279 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--CLK 1074 Q +HRDL +N+L++ +K+ DFGLA+A + Y + WY P L Sbjct 280 QKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTY----SNEVVTLWYRPPDILLG 335 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + D+W G YE+ T Sbjct 336 STDYSTQIDMWGVGCIFYEMAT 357 Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust. Identities = 61/271 (23%), Positives = 106/271 (39%), Gaps = 57/271 (21%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 R ++LS++ F +++ +L LG+GT VY+G+ K+ D Sbjct 150 RRVSLSEIGFGKLET--YIKLDKLGEGTYATVYKGK-----------SKLTDN------- 189 Query 632 DRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 V LK + H + A A E SL+ + H ++ +H + +V EY Sbjct 190 ------LVALKEIRLEHEEGAPCTAIRE-VSLLKDLKHANIVTLHDIIHTEKSLTLVFEY 242 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 ++ L +L + M + QL L+Y + ++H ++ +N+L+ G Sbjct 243 LDKD-LKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERG--- 298 Query 750 GTSPFIKLSDPGVGLGALSREERVERIP-----------WLAPECLPGGANSLSTAMDKW 798 +KL+D G+ R + IP W P + G+ ST +D W Sbjct 299 ----ELKLADFGLA--------RAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMW 346 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 G G E+ G + E+ HF R Sbjct 347 GVGCIFYEMA-TGRPLFPGSTVEEQLHFIFR 376 >sp|Q54MV2|MRKB_DICDI Probable serine/threonine-protein kinase MARK-B OS=Dictyostelium discoideum OX=44689 GN=mrkB PE=3 SV=1 Length=715 Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 62/198 (31%), Positives = 98/198 (49%), Gaps = 11/198 (6%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 + +G G KV + TN TG+ A+K K + R ++EI IL+ L H++II Sbjct 69 KTIGSGTSSKVKI----GTNILTGKQYAIKITKPK-RIKERKEIEREISILKRLKHDNII 123 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + + + L++E V G L DY+ R + + F +Q+ G+ Y H+ Sbjct 124 QLHDAIYEDDVGRICLILELVSGGELFDYIVARGRLSEKEGRKFFRQMLCGLIYCHSNMV 183 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 HRDL N+L+D D +KI DFG + + G+ + SPV+ PE L E ++ Sbjct 184 CHRDLKLENLLVDEDGNLKISDFGYSNIIKPGN---LLSTFCGSPVYA-PPEILLEKRYN 239 Query 1080 -YASDVWSFGVTLYELLT 1096 D+WS GV LY ++T Sbjct 240 GNEVDIWSMGVILYAMVT 257 >sp|Q8GWJ7|CRK19_ARATH Cysteine-rich receptor-like protein kinase 19 OS=Arabidopsis thaliana OX=3702 GN=CRK19 PE=1 SV=2 Length=645 Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 84/289 (29%), Positives = 132/289 (46%), Gaps = 34/289 (12%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I LG+G FG+V Y T +G VAVK L G Q ++ E+ ++ L H ++ Sbjct 329 INKLGQGGFGEV----YKGTL-SSGLQVAVKRLSKTSG-QGEKEFENEVVVVAKLQHRNL 382 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL----AQLLLFAQQICEGMAYLH 1015 +K G C + EK L V E+VP SL +L ++ + + I G+ YLH Sbjct 383 VKLLGYCLEGEEKIL--VYEFVPNKSLDHFLFDSTMKMKLDWTRRYKIIGGIARGILYLH 440 Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 IHRDL A N+LLD+D KI DFG+A+ R + + +PE Sbjct 441 QDSRLTIIHRDLKAGNILLDDDMNPKIADFGMARIFGMDQTEAMTRRVVGT-YGYMSPEY 499 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL--RL------ 1124 +F SDV+SFGV + E+++ +S L + + G + RL Sbjct 500 AMYGQFSMKSDVYSFGVLVLEIISGMKNSS------LYQMDESVGNLVTYTWRLWSNGSP 553 Query 1125 TELLE--RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +EL++ G+ + C H+ C + +A RPT +++ +L T Sbjct 554 SELVDPSFGDNYQTSEITRC--IHIALLCVQEDAEDRPTMSSIVQMLTT 600 Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust. Identities = 54/227 (24%), Positives = 96/227 (42%), Gaps = 45/227 (20%) Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651 ++ LGQG VY+G L SG L+V +K L + Sbjct 329 INKLGQGGFGEVYKGTL---SSG----------------------LQVAVKRLSKTSGQG 363 Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW- 710 F +++++ H +L + G C+ G E I+V E+V + LD +L + + W Sbjct 364 EKEFENEVVVVAKLQHRNLVKLLGYCLEGEEKILVYEFVPNKSLDHFLFDSTMKMKLDWT 423 Query 711 -KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--L 764 + + +A + YL + ++H ++ NIL L + +P K++D G+ Sbjct 424 RRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNIL-----LDDDMNP--KIADFGMARIF 476 Query 765 GALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 G E R+ +++PE G S+ + D + FG +LEI Sbjct 477 GMDQTEAMTRRVVGTYGYMSPEYAMYGQFSMKS--DVYSFGVLVLEI 521 >sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo sapiens OX=9606 GN=CHEK1 PE=1 SV=2 Length=476 Score = 81.6 bits (200), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 68/200 (34%), Positives = 99/200 (50%), Gaps = 13/200 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 ++ LGEG +G+V L N T E VAVK + K+EI I + L HE++ Sbjct 12 VQTLGEGAYGEVQL----AVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENV 67 Query 960 IKYKGCCEDQGEKSLQ-LVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHA 1016 +K+ G + E ++Q L +EY G L D + IG+ + F Q+ G+ YLH Sbjct 68 VKFYG---HRREGNIQYLFLEYCSGGELFDRI-EPDIGMPEPDAQRFFHQLMAGVVYLHG 123 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 HRD+ N+LLD +KI DFGLA V + R+ + + APE LK Sbjct 124 IGITHRDIKPENLLLDERDNLKISDFGLA-TVFRYNNRERLLNKMCGTLPYVAPELLKRR 182 Query 1077 KFYYA-SDVWSFGVTLYELL 1095 +F+ DVWS G+ L +L Sbjct 183 EFHAEPVDVWSCGIVLTAML 202 >sp|O75385|ULK1_HUMAN Serine/threonine-protein kinase ULK1 OS=Homo sapiens OX=9606 GN=ULK1 PE=1 SV=2 Length=1050 Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 60/180 (33%), Positives = 86/180 (48%), Gaps = 16/180 (9%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VAVK + + ++ +EI IL+ L HE+I+ E S+ LVMEY G L Sbjct 43 VAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEM--ANSVYLVMEYCNGGDL 100 Query 987 RDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR---------L 1036 DYL ++ + LF QQI M LH++ IHRDL +N+LL N Sbjct 101 ADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIR 160 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 VKI DFG A+ + SP++ APE + + +D+WS G +Y+ LT Sbjct 161 VKIADFGFARYL---QSNMMAATLCGSPMYM-APEVIMSQHYDGKADLWSIGTIVYQCLT 216 Score = 46.6 bits (109), Expect = 0.002, Method: Compositional matrix adjust. Identities = 43/178 (24%), Positives = 81/178 (46%), Gaps = 9/178 (5%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 ++ ++ H ++ ++ +V EY G L +L R ++ + QQ+A Sbjct 66 ILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFL-QQIAG 124 Query 721 ALSYLENKNLVHGNVCGRNILLARLG--LAEGTSPFIKLSDPGVG--LGALSREERVERI 776 A+ L +K ++H ++ +NILL+ A S +K++D G L + + Sbjct 125 AMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGS 184 Query 777 P-WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833 P ++APE + + D W G T++ C G+AP Q+ SP + FY++ L Sbjct 185 PMYMAPEVI--MSQHYDGKADLWSIG-TIVYQCLTGKAPFQASSPQDLRLFYEKNKTL 239 >sp|Q5PU49|KPCD_CANLF Protein kinase C delta type OS=Canis lupus familiaris OX=9615 GN=PRKCD PE=2 SV=1 Length=674 Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 71/226 (31%), Positives = 105/226 (46%), Gaps = 34/226 (15%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 D +FHK LG+G FGKV L G E A+KALK D + Sbjct 345 DNFIFHKV-------LGKGSFGKVLLV----ELKGKKEFFAIKALKKDVVLI-------D 386 Query 948 IDILRTLYHEHIIKYKG--------CCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLA 998 D+ T+ + ++ C Q + L VME++ G L ++ + L Sbjct 387 DDVECTMVEKRVLALAWENPFLTHLFCTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELY 446 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 + +A +I G+ +LH + I+RDL NV+LD D +KI DFG+ K G + + Sbjct 447 RATFYAAEIVCGLQFLHNKGIIYRDLKLDNVMLDQDGHIKIADFGMCKENIFGEK--QAS 504 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 +P + APE L+ K+ ++ D WSFGV LYE+L QSP Sbjct 505 TFCGTPDY-IAPEILQGLKYSFSVDWWSFGVLLYEMLI----GQSP 545 Score = 42.7 bits (99), Expect = 0.024, Method: Compositional matrix adjust. Identities = 42/183 (23%), Positives = 82/183 (45%), Gaps = 19/183 (10%) Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 V E++ G L ++ +++G + A ++ L +L NK +++ ++ N++L Sbjct 422 FFVMEFLNGGDL-MYHIQDKGRFELYRATFYAAEIVCGLQFLHNKGIIYRDLKLDNVMLD 480 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSLSTAMDKWG 799 + G IK++D G+ + E++ ++APE L G S S +D W Sbjct 481 QDG-------HIKIADFGMCKENIFGEKQASTFCGTPDYIAPEILQGLKYSFS--VDWWS 531 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859 FG L E+ G++P E E F R+ P P+ T S+ + + +R + Sbjct 532 FGVLLYEMLI-GQSPFH--GDDEDELF--ESIRVDTPHYPRWITKESKDILEKLLERDTT 586 Query 860 RTI 862 + + Sbjct 587 KRL 589 >sp|Q60680|IKKA_MOUSE Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Mus musculus OX=10090 GN=Chuk PE=1 SV=1 Length=745 Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 63/206 (31%), Positives = 96/206 (47%), Gaps = 24/206 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG VSLY + + +A+K+ + + ++R W EI I++ L H +++K Sbjct 21 LGTGGFGNVSLYQHRELDLK----IAIKSCRLELSSKNRERWCHEIQIMKKLDHANVVK- 75 Query 963 KGCCEDQGEKSLQ------LVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMA 1012 C+ E + L MEY G LR L P + GL +Q+L I G+ Sbjct 76 --ACDVPEELNFLINDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIR 133 Query 1013 YLHAQHYIHRDLAARNVLLDN---DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH IHRDL N++L + + KI D G AK V +G + + + A Sbjct 134 YLHENKIIHRDLKPENIVLQDVGGKTIHKIIDLGYAKDVDQG----SLCTSFVGTLQYLA 189 Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095 PE + + D WSFG ++E + Sbjct 190 PELFENKPYTATVDYWSFGTMVFECI 215 >sp|O55092|SLK_CAVPO STE20-like serine/threonine-protein kinase OS=Cavia porcellus OX=10141 GN=SLK PE=1 SV=1 Length=1231 Score = 82.8 bits (203), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 61/205 (30%), Positives = 99/205 (48%), Gaps = 23/205 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I +LG+G FGKV Y N T + A K + + + EIDIL + H +I Sbjct 37 IGELGDGAFGKV----YKAQNKETNVLAAAKVIDTKS-EEELEDYMVEIDILASCDHPNI 91 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQ 1017 +K E +L +++E+ G++ + + +Q+ + +Q E + YLH Sbjct 92 VKLLDAF--YYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDN 149 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---FWYAPECL- 1073 IHRDL A N+L D +K+ DFG++ + R + DS + +W APE + Sbjct 150 KIIHRDLKAGNILFTLDGDIKLADFGVS------AKNTRTIQRRDSFIGTPYWMAPEVVM 203 Query 1074 ----KEYKFYYASDVWSFGVTLYEL 1094 K+ + Y +DVWS G+TL E+ Sbjct 204 CETSKDRPYDYKADVWSLGITLIEM 228 Score = 40.8 bits (94), Expect = 0.11, Method: Compositional matrix adjust. Identities = 31/103 (30%), Positives = 44/103 (43%), Gaps = 14/103 (14%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG---ALSR 769 VV +Q AL+YL + ++H ++ NIL G IKL+D GV + R Sbjct 134 VVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDG-------DIKLADFGVSAKNTRTIQR 186 Query 770 EERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808 + P W+APE C D W G TL+E+ Sbjct 187 RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMA 229 >sp|Q63686|CDK16_RAT Cyclin-dependent kinase 16 OS=Rattus norvegicus OX=10116 GN=Cdk16 PE=1 SV=2 Length=496 Score = 81.6 bits (200), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 60/202 (30%), Positives = 94/202 (47%), Gaps = 15/202 (7%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 K+ LGEG + V Y + T +VA+K ++ + +E+ +L+ L H + Sbjct 167 KLDKLGEGTYATV----YKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHAN 222 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHA 1016 I+ EKSL LV EY+ L+ YL + I + + LF Q+ G+AY H Sbjct 223 IVTLHDII--HTEKSLTLVFEYLD-KDLKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHR 279 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--CLK 1074 Q +HRDL +N+L++ +K+ DFGLA+A + Y + WY P L Sbjct 280 QKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTY----SNEVVTLWYRPPDILLG 335 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + D+W G YE+ T Sbjct 336 STDYSTQIDMWGVGCIFYEMAT 357 Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust. Identities = 61/271 (23%), Positives = 106/271 (39%), Gaps = 57/271 (21%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 R ++LS++ F +++ +L LG+GT VY+G+ K+ D Sbjct 150 RRVSLSEIGFGKLET--YIKLDKLGEGTYATVYKGK-----------SKLTDN------- 189 Query 632 DRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 V LK + H + A A E SL+ + H ++ +H + +V EY Sbjct 190 ------LVALKEIRLEHEEGAPCTAIRE-VSLLKDLKHANIVTLHDIIHTEKSLTLVFEY 242 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 ++ L +L + M + QL L+Y + ++H ++ +N+L+ G Sbjct 243 LDKD-LKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERG--- 298 Query 750 GTSPFIKLSDPGVGLGALSREERVERIP-----------WLAPECLPGGANSLSTAMDKW 798 +KL+D G+ R + IP W P + G+ ST +D W Sbjct 299 ----ELKLADFGLA--------RAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMW 346 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 G G E+ G + E+ HF R Sbjct 347 GVGCIFYEMA-TGRPLFPGSTVEEQLHFIFR 376 >sp|P87248|ATG1_COLLN Serine/threonine-protein kinase ATG1 OS=Colletotrichum lindemuthianum OX=290576 GN=ATG1 PE=3 SV=1 Length=675 Score = 82.4 bits (202), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 78/316 (25%), Positives = 130/316 (41%), Gaps = 73/316 (23%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHII 960 ++G+G F +V Y + + VA+K+++ + R EI IL+TL H HI+ Sbjct 30 EIGKGSFAQV----YSGHHKNSKAAVAIKSVEMGRLNNKLRENLYGEIQILKTLRHPHIV 85 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSI-----------------GLAQL 1000 C E + LVMEY LG L ++ RH GL ++ Sbjct 86 ALHDCVESATH--INLVMEYCELGDLSFFIKKRDRHGTNAATEDMARKYPVTPGSGLHEV 143 Query 1001 LL--FAQQICEGMAYLHAQHYIHRDLAARNVLL-----------------DNDRLV---- 1037 + F QQ+ + +L ++Y+HRD+ +N+LL ND L+ Sbjct 144 VTRHFLQQLASALKFLREKNYVHRDVKPQNLLLLPSPGFRKENSRPILTASNDSLIPNAG 203 Query 1038 -------KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 K+ DFG A+ +P + SP++ APE L+ ++ +D+WS G Sbjct 204 LASLPMLKLADFGFARVLPSTSLADTL---CGSPLYM-APEILRYERYDAKADLWSVGTV 259 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 LYE++T PP + A+ + +LR E E + P+ ++ L+ Sbjct 260 LYEMIT-----GRPPFR-------ARNHVELLRKIEATEDKVKYPKDAVVSKDLVKLIGK 307 Query 1151 CWETEASFRPTFENLI 1166 R FE+ Sbjct 308 LLTRNPVERMRFEDFF 323 Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 68/263 (26%), Positives = 102/263 (39%), Gaps = 58/263 (22%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGH------VP 707 Y ++ + H H+ +H CV +I +V EY E G L ++++ H Sbjct 69 LYGEIQILKTLRHPHIVALHD-CVESATHINLVMEYCELGDLSFFIKKRDRHGTNAATED 127 Query 708 MAWKMVVA--------------QQLASALSYLENKNLVHGNVCGRNILL----------- 742 MA K V QQLASAL +L KN VH +V +N+LL Sbjct 128 MARKYPVTPGSGLHEVVTRHFLQQLASALKFLREKNYVHRDVKPQNLLLLPSPGFRKENS 187 Query 743 ------------ARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIP-WLAPECLPGG 787 GLA + P +KL+D G L + S + + P ++APE L Sbjct 188 RPILTASNDSLIPNAGLA--SLPMLKLADFGFARVLPSTSLADTLCGSPLYMAPEIL--R 243 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE---KEHFYQRQHRLPEPSC--PQLA 842 D W G L E+ G P ++R+ E K + + + P+ + L Sbjct 244 YERYDAKADLWSVGTVLYEM-ITGRPPFRARNHVELLRKIEATEDKVKYPKDAVVSKDLV 302 Query 843 TLTSQCLTYEPTQRPSFRTILRD 865 L + LT P +R F D Sbjct 303 KLIGKLLTRNPVERMRFEDFFND 325 >sp|Q9UIK4|DAPK2_HUMAN Death-associated protein kinase 2 OS=Homo sapiens OX=9606 GN=DAPK2 PE=1 SV=1 Length=370 Score = 80.5 bits (197), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 66/227 (29%), Positives = 110/227 (48%), Gaps = 26/227 (11%) Query 884 SPASDPTVFHKRYLKKIRDLGE----GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 SP +P F ++ ++ D+GE G F V C + + TG A K +K Sbjct 8 SPNMEP--FKQQKVEDFYDIGEELGSGQFAIVK-KCREKS---TGLEYAAKFIKKRQSRA 61 Query 940 HRSG-----WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RH 993 R G ++E+ ILR + H ++I E++ + + L++E V G L D+L + Sbjct 62 SRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTD--VVLILELVSGGELFDFLAQKE 119 Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL----VKIGDFGLAKAVP 1049 S+ + F +QI +G+ YLH + H DL N++L + + +K+ DFGLA + Sbjct 120 SLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIE 179 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 +G E+ + +P F APE + +D+WS GV Y LL+ Sbjct 180 DGVEFKNI---FGTPEF-VAPEIVNYEPLGLEADMWSIGVITYILLS 222 Score = 35.4 bits (80), Expect = 3.0, Method: Compositional matrix adjust. Identities = 42/171 (25%), Positives = 71/171 (42%), Gaps = 18/171 (11%) Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQ 717 S++ QV H ++ +H V + +++ E V G L D ++E A + +Q Sbjct 75 VSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFI--KQ 132 Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE--- 774 + ++YL K + H ++ NI+L + P IKL D G+ A E+ VE Sbjct 133 ILDGVNYLHTKKIAHFDLKPENIMLLDKNIP---IPHIKLIDFGL---AHEIEDGVEFKN 186 Query 775 ---RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 ++APE + L D W G + I G +P + E Sbjct 187 IFGTPEFVAPEIV--NYEPLGLEADMWSIGV-ITYILLSGASPFLGDTKQE 234 >sp|Q9WUT3|KS6A2_MOUSE Ribosomal protein S6 kinase alpha-2 OS=Mus musculus OX=10090 GN=Rps6ka2 PE=1 SV=1 Length=733 Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 62/212 (29%), Positives = 108/212 (51%), Gaps = 13/212 (6%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWK 945 +DP+ F + ++ LG+G +GKV L T G++ A+K LK A + R K Sbjct 54 ADPSQF-----ELLKVLGQGSYGKVFL-VRKVTGSDAGQLYAMKVLKKATLKVRDRVRSK 107 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ-LLLFA 1004 E DIL + H I+K + +G+ L L+++++ G L L + + + + + Sbjct 108 MERDILAEVNHPFIVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYL 165 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 ++ + +LH I+RDL N+LLD + +KI DFGL+K E ++ + Sbjct 166 AELALALDHLHGLGIIYRDLKPENILLDEEGHIKITDFGLSK---EATDHDKRAYSFCGT 222 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 + + APE + ++D WSFGV ++E+LT Sbjct 223 IEYMAPEVVNRRGHTQSADWWSFGVLMFEMLT 254 Score = 63.9 bits (154), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 62/185 (34%), Positives = 86/185 (46%), Gaps = 29/185 (16%) Query 946 QEIDIL-RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLL 1001 +EI+IL R H +II K +D K + LVME + G L D + R S A + Sbjct 455 EEIEILLRYGQHPNIITLKDVYDDG--KYVYLVMELMRGGELLDRILRQRCFSEREASDV 512 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRV 1057 L+ I M YLH+Q +HRDL N+L N ++I DFG AK + Sbjct 513 LYT--IARTMDYLHSQGVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLRA------- 563 Query 1058 REDG--DSPVF---WYAPECLKEYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKF 1108 E+G +P + + APE LK + A DVWS G+ LY +L + P + Sbjct 564 -ENGLLMTPCYTANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPDDTPEEI 622 Query 1109 LELIG 1113 L IG Sbjct 623 LARIG 627 >sp|Q0UY20|ATG1_PHANO Serine/threonine-protein kinase atg1 OS=Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) OX=321614 GN=ATG1 PE=3 SV=2 Length=972 Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 75/321 (23%), Positives = 134/321 (42%), Gaps = 78/321 (24%) Query 897 LKKIRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRT 953 K++ +G+G F +V ++ T + VA+K++ + + + EI ILR+ Sbjct 30 FKRMDHIGKGSFAEVYRGIHIVPNTQQEKRQSVAIKSVNMNKLNKKLKDNLVSEISILRS 89 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI------------------ 995 L+H HI+ C E + ++ME+ LG L ++ + + Sbjct 90 LHHPHIVSLIDCHETPSR--MHIIMEFCELGDLSAFIKKRADLVNHPQTQRMIEKYPNPA 147 Query 996 --GLAQLLL--FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR---------------- 1035 GL ++++ FA+Q+ + +L +++YIHRDL +N+LL+ Sbjct 148 VGGLNEVIVRHFAKQMASALEFLRSKNYIHRDLKPQNLLLNPSSVYYSQSGTLERMPLAA 207 Query 1036 ---------------LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 ++KI DFG A+ +P + E + APE L+ K+ Sbjct 208 DASSLLPATGIESLPMLKIADFGFARILPTTS----LAETLCGSPLYMAPEILRYEKYDA 263 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 +D+WS G L+E++ C PP + A + +LR E ER + + P+ Sbjct 264 KADLWSVGTVLFEMM--C---ARPPFR-------ANNHVELLRKIE--ERKDHIRFPEGI 309 Query 1141 PCEVYHLMKNCWETEASFRPT 1161 C MKN +PT Sbjct 310 VCS--RAMKNLIRALLKRKPT 328 Score = 41.2 bits (95), Expect = 0.073, Method: Compositional matrix adjust. Identities = 71/334 (21%), Positives = 125/334 (37%), Gaps = 85/334 (25%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 ++ H+G+G+ VY G +VP + + V +K ++ + + Sbjct 32 RMDHIGKGSFAEVYRGIH------------------IVPNTQQEKRQSVAIKSVNMNKLN 73 Query 651 IALA--FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHV- 706 L S++ + H H+ + C P + ++ E+ E G L ++++ V Sbjct 74 KKLKDNLVSEISILRSLHHPHIVSLID-CHETPSRMHIIMEFCELGDLSAFIKKRADLVN 132 Query 707 -PMAWKMV------------------VAQQLASALSYLENKNLVHGNVCGRNIL------ 741 P +M+ A+Q+ASAL +L +KN +H ++ +N+L Sbjct 133 HPQTQRMIEKYPNPAVGGLNEVIVRHFAKQMASALEFLRSKNYIHRDLKPQNLLLNPSSV 192 Query 742 -------LARLGLAEGTS-----------PFIKLSDPGVG--LGALSREERVERIP-WLA 780 L R+ LA S P +K++D G L S E + P ++A Sbjct 193 YYSQSGTLERMPLAADASSLLPATGIESLPMLKIADFGFARILPTTSLAETLCGSPLYMA 252 Query 781 PECLPGGANSLSTAMDKWGFGATLLEIC-------FDGEAPLQSRSPSEKEHFYQRQHRL 833 PE L D W G L E+ + L + K+H R Sbjct 253 PEIL--RYEKYDAKADLWSVGTVLFEMMCARPPFRANNHVELLRKIEERKDHI-----RF 305 Query 834 PEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRD 865 PE C + + L L +PT+R S+ + D Sbjct 306 PEGIVCSRAMKNLIRALLKRKPTERMSYDSFFSD 339 >sp|O64556|Y2923_ARATH Putative leucine-rich repeat receptor-like serine/threonine-protein kinase At2g19230 OS=Arabidopsis thaliana OX=3702 GN=At2g19230 PE=1 SV=3 Length=877 Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 60/203 (30%), Positives = 102/203 (50%), Gaps = 18/203 (9%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LG+G FGKV GE VA+K L ++ ++ E+++L ++H+++I Sbjct 573 RVLGQGGFGKVYYGVL------RGEQVAIKMLSKSSAQGYKE-FRAEVELLLRVHHKNLI 625 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLH-- 1015 G C + + + L+ EY+ G+L DYL + + + L + +G+ YLH Sbjct 626 ALIGYCHEGDQ--MALIYEYIGNGTLGDYLSGKNSSILSWEERLQISLDAAQGLEYLHNG 683 Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECL 1073 +HRD+ N+L++ KI DFGL+++ EG +V + + + PE Sbjct 684 CKPPIVHRDVKPTNILINEKLQAKIADFGLSRSFTLEGDS--QVSTEVAGTIGYLDPEHY 741 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 +F SDV+SFGV L E++T Sbjct 742 SMQQFSEKSDVYSFGVVLLEVIT 764 Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust. Identities = 63/254 (25%), Positives = 102/254 (40%), Gaps = 54/254 (21%) Query 588 EITQLSH-----LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 EI ++++ LGQG VY G LR E +V +K Sbjct 563 EIVEITNNFERVLGQGGFGKVYYGVLRGE--------------------------QVAIK 596 Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 +L S F L+ +V H +L + G C G + ++ EY+ +G L +L + Sbjct 597 MLSKSSAQGYKEFRAEVELLLRVHHKNLIALIGYCHEGDQMALIYEYIGNGTLGDYLSGK 656 Query 703 RGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + ++W ++ ++ A L YL N +VH +V NIL+ A K+ Sbjct 657 NSSI-LSWEERLQISLDAAQGLEYLHNGCKPPIVHRDVKPTNILINEKLQA-------KI 708 Query 758 SDPGVGLG-ALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 +D G+ L + +V I +L PE S D + FG LLE+ Sbjct 709 ADFGLSRSFTLEGDSQVSTEVAGTIGYLDPEHY--SMQQFSEKSDVYSFGVVLLEVI--T 764 Query 812 EAPLQSRSPSEKEH 825 P+ SRS +E+ Sbjct 765 GQPVISRSRTEENR 778 >sp|Q97PA9|STKP_STRPN Serine/threonine-protein kinase StkP OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=stkP PE=1 SV=1 Length=659 Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 63/209 (30%), Positives = 99/209 (47%), Gaps = 11/209 (5%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEI 948 +F RY + ++ +G G V L D DG E VAVK L+ + P + +++E Sbjct 7 IFAGRY-RIVKQIGRGGMADVYL-AKDLILDG--EEVAVKVLRTNYQTDPIAVARFQREA 62 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQI 1007 + L H HI++ E+ G++ L MEYV L+ Y+ H + + + QI Sbjct 63 RAMADLDHPHIVRITDIGEEDGQQ--YLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQI 120 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 M H + +HRDL +N+LL D K+ DFG+A A E G V + Sbjct 121 LLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVAFAETSLTQTNSMLGS--VHY 178 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096 +PE + K SD+++ G+ YE+LT Sbjct 179 LSPEQARGSKATVQSDIYAMGIIFYEMLT 207 Score = 35.0 bits (79), Expect = 5.3, Method: Compositional matrix adjust. Identities = 52/222 (23%), Positives = 96/222 (43%), Gaps = 39/222 (18%) Query 639 VVLKVLDPSHHD--IALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +KVL ++ IA+A F A M+ + H H+ + + + + EYV L Sbjct 39 VAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDL 98 Query 696 DVWLRRERGHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 +++ H P++ + V Q+ A+ + +VH ++ +NILL G A Sbjct 99 KRYIKE---HYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTA----- 150 Query 754 FIKLSDPGVGLG----ALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLE-- 806 K++D G+ + +L++ + + +L+PE G ++ + D + G E Sbjct 151 --KVTDFGIAVAFAETSLTQTNSMLGSVHYLSPEQARGSKATVQS--DIYAMGIIFYEML 206 Query 807 ---ICFDGEAPLQSRSPSEKEHFYQRQHRLP-----EPSCPQ 840 I +DG++ + +HF Q LP PS PQ Sbjct 207 TGHIPYDGDSAVT----IALQHF---QKPLPSVIAENPSVPQ 241 >sp|Q3ZDQ4|ATG1_PODAS Serine/threonine-protein kinase ATG1 OS=Podospora anserina OX=2587412 GN=ATG1 PE=2 SV=1 Length=941 Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 76/318 (24%), Positives = 130/318 (41%), Gaps = 75/318 (24%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHI 959 +++G+G F +V Y + TG +VA+K+++ + + + EI IL+TL H HI Sbjct 30 KEIGKGSFAQV----YSGRHKVTGALVAIKSVELSRLNKKLKENLYGEIKILKTLRHPHI 85 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSL--------------------RDYLPRHSIGLAQ 999 + C E + L+MEY LG L R Y H+ GL + Sbjct 86 VALHDCVESATH--INLIMEYCELGDLSLFIKKREKLITHSATRDIARRYPIEHNQGLHE 143 Query 1000 LLL--FAQQICEGMAYLHAQHYIHRDLAARNVLL-------------------DNDRLV- 1037 ++ F +Q+ + +L +++HRD+ +N+LL D L+ Sbjct 144 VITRHFLKQLASALKFLREGNFVHRDVKPQNLLLLPSPLFRETHHSAKQILSASYDSLMP 203 Query 1038 ----------KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 K+ DFG A+ +P + E + APE L+ ++ +D+WS Sbjct 204 AAGLPSLPMLKLADFGFARVLPSTS----LAETLCGSPLYMAPEILRYERYDAKADLWSV 259 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 G LYE+ T PP + A + +LR E E + PR E+ L Sbjct 260 GTVLYEMATG-----RPPFR-------AGNHVELLRKIEAAEDQVKFPRESVVSPELKSL 307 Query 1148 MKNCWETEASFRPTFENL 1165 ++ + R +F + Sbjct 308 VRALLKRNPVERISFADF 325 Score = 47.8 bits (112), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 74/319 (23%), Positives = 122/319 (38%), Gaps = 82/319 (26%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 +G+G+ VY GR +V G+ V +K ++ S + L Sbjct 32 IGKGSFAQVYSGRHKVTGA------------------------LVAIKSVELSRLNKKLK 67 Query 655 --FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWK 711 Y ++ + H H+ +H CV +I ++ EY E G L +++++ + + Sbjct 68 ENLYGEIKILKTLRHPHIVALHD-CVESATHINLIMEYCELGDLSLFIKKREKLITHSAT 126 Query 712 MVVA--------------------QQLASALSYLENKNLVHGNVCGRNILL--------- 742 +A +QLASAL +L N VH +V +N+LL Sbjct 127 RDIARRYPIEHNQGLHEVITRHFLKQLASALKFLREGNFVHRDVKPQNLLLLPSPLFRET 186 Query 743 ---ARLGLAEG-----------TSPFIKLSDPGVG--LGALSREERVERIP-WLAPECLP 785 A+ L+ + P +KL+D G L + S E + P ++APE L Sbjct 187 HHSAKQILSASYDSLMPAAGLPSLPMLKLADFGFARVLPSTSLAETLCGSPLYMAPEIL- 245 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE---KEHFYQRQHRLPEPSC--PQ 840 D W G L E+ G P ++ + E K + Q + P S P+ Sbjct 246 -RYERYDAKADLWSVGTVLYEMA-TGRPPFRAGNHVELLRKIEAAEDQVKFPRESVVSPE 303 Query 841 LATLTSQCLTYEPTQRPSF 859 L +L L P +R SF Sbjct 304 LKSLVRALLKRNPVERISF 322 >sp|Q8DNS0|STKP_STRR6 Serine/threonine-protein kinase StkP OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=stkP PE=1 SV=1 Length=659 Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 63/209 (30%), Positives = 99/209 (47%), Gaps = 11/209 (5%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEI 948 +F RY + ++ +G G V L D DG E VAVK L+ + P + +++E Sbjct 7 IFAGRY-RIVKQIGRGGMADVYL-AKDLILDG--EEVAVKVLRTNYQTDPIAVARFQREA 62 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQI 1007 + L H HI++ E+ G++ L MEYV L+ Y+ H + + + QI Sbjct 63 RAMADLDHPHIVRITDIGEEDGQQ--YLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQI 120 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 M H + +HRDL +N+LL D K+ DFG+A A E G V + Sbjct 121 LLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVAFAETSLTQTNSMLGS--VHY 178 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096 +PE + K SD+++ G+ YE+LT Sbjct 179 LSPEQARGSKATVQSDIYAMGIIFYEMLT 207 >sp|Q04J43|STKP_STRP2 Serine/threonine-protein kinase StkP OS=Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) OX=373153 GN=stkP PE=1 SV=1 Length=659 Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 63/209 (30%), Positives = 99/209 (47%), Gaps = 11/209 (5%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEI 948 +F RY + ++ +G G V L D DG E VAVK L+ + P + +++E Sbjct 7 IFAGRY-RIVKQIGRGGMADVYL-AKDLILDG--EEVAVKVLRTNYQTDPIAVARFQREA 62 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQI 1007 + L H HI++ E+ G++ L MEYV L+ Y+ H + + + QI Sbjct 63 RAMADLDHPHIVRITDIGEEDGQQ--YLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQI 120 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 M H + +HRDL +N+LL D K+ DFG+A A E G V + Sbjct 121 LLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVAFAETSLTQTNSMLGS--VHY 178 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096 +PE + K SD+++ G+ YE+LT Sbjct 179 LSPEQARGSKATVQSDIYAMGIIFYEMLT 207 >sp|Q7TSC3|NEK5_MOUSE Serine/threonine-protein kinase Nek5 OS=Mus musculus OX=10090 GN=Nek5 PE=2 SV=1 Length=627 Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 55/201 (27%), Positives = 98/201 (49%), Gaps = 16/201 (8%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I+ +GEG FGKV Y + +K + + + K E+ +L + H +I Sbjct 7 IKIIGEGTFGKV----YLAKDKSESSHCVIKEISL---TKEKEASKNEVILLARMEHPNI 59 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA 1016 + + ++ G L +VMEY G L + R Q+L + QI G+ ++H Sbjct 60 VTFFSSFQENGR--LFIVMEYCDGGDLMQRIQRQRGVMFSEDQILCWFVQISLGLKHIHD 117 Query 1017 QHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + +HRD+ ++N+ L + +V K+GDFG A+ + + E + +P ++ +PE + Sbjct 118 RKILHRDIKSQNIFLSKNGMVAKLGDFGTARTLNDSMELAQTC--AGTP-YYLSPEICQN 174 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 + +D+WS G LYEL T Sbjct 175 RPYNNKTDIWSLGCVLYELCT 195 Score = 40.8 bits (94), Expect = 0.084, Method: Compositional matrix adjust. Identities = 53/254 (21%), Positives = 103/254 (41%), Gaps = 42/254 (17%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETAS-----LMSQVSHTHLAFVHGVCVRGPENI 684 +D+ + V+K +I+L + AS L++++ H ++ Sbjct 21 AKDKSESSHCVIK-------EISLTKEKEASKNEVILLARMEHPNIVTFFSSFQENGRLF 73 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILL 742 +V EY + G L ++R+RG V + ++ Q++ L ++ ++ ++H ++ +NI L Sbjct 74 IVMEYCDGGDLMQRIQRQRG-VMFSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFL 132 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP----WLAPECLPGGANSLSTAMDKW 798 ++ G+ KL D G E + +L+PE + T D W Sbjct 133 SKNGMV------AKLGDFGTARTLNDSMELAQTCAGTPYYLSPEICQNRPYNNKT--DIW 184 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE----PSCP----QLATLTSQCLT 850 G L E+C + P E +F+ ++ + P P L +L Q Sbjct 185 SLGCVLYELC-------TLKHPFESNNFHHLVLKICQGRVAPISPHFSRDLQSLIPQLFR 237 Query 851 YEPTQRPSFRTILR 864 P RPS ++L+ Sbjct 238 VSPQDRPSVTSLLK 251 >sp|Q0WVM4|Y2239_ARATH Probable LRR receptor-like serine/threonine-protein kinase At2g23950 OS=Arabidopsis thaliana OX=3702 GN=At2g23950 PE=1 SV=1 Length=634 Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 65/198 (33%), Positives = 93/198 (47%), Gaps = 13/198 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + G G +VAVK LK G S ++ E++++ H ++++ Sbjct 305 LGAGGFGNVYRGKF-----GDGTVVAVKRLKDVNGTSGNSQFRTELEMISLAVHRNLLRL 359 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQ---H 1018 G C E+ LV Y+ GS+ L + ++ A G+ YLH Q Sbjct 360 IGYCASSSER--LLVYPYMSNGSVASRLKAKPALDWNTRKKIAIGAARGLFYLHEQCDPK 417 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ A N+LLD +GDFGLAK + HE V V APE L + Sbjct 418 IIHRDVKAANILLDEYFEAVVGDFGLAKLL--NHEDSHVTTAVRGTVGHIAPEYLSTGQS 475 Query 1079 YYASDVWSFGVTLYELLT 1096 +DV+ FG+ L EL+T Sbjct 476 SEKTDVFGFGILLLELIT 493 >sp|Q9FII5|TDR_ARATH Leucine-rich repeat receptor-like protein kinase TDR OS=Arabidopsis thaliana OX=3702 GN=TDR PE=1 SV=1 Length=1041 Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 60/188 (32%), Positives = 91/188 (48%), Gaps = 20/188 (11%) Query 923 TGEMVAVKAL---KADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLV 977 GE++AVK L + G R SG E+D+L + H +I++ GCC ++ L+ Sbjct 740 NGEIIAVKKLWGKNKENGKIRRRKSGVLAEVDVLGNVRHRNIVRLLGCCTNR--DCTMLL 797 Query 978 MEYVPLGSLRDYL---PRHSIGLAQ---LLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028 EY+P GSL D L + A+ L A + +G+ YLH +HRDL N Sbjct 798 YEYMPNGSLDDLLHGGDKTMTAAAEWTALYQIAIGVAQGICYLHHDCDPVIVHRDLKPSN 857 Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 +LLD D ++ DFG+AK + V + APE + SD++S+G Sbjct 858 ILLDADFEARVADFGVAKLIQTDESMSVVA----GSYGYIAPEYAYTLQVDKKSDIYSYG 913 Query 1089 VTLYELLT 1096 V L E++T Sbjct 914 VILLEIIT 921 >sp|O22476|BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 OS=Arabidopsis thaliana OX=3702 GN=BRI1 PE=1 SV=1 Length=1196 Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 78/293 (27%), Positives = 131/293 (45%), Gaps = 27/293 (9%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 FH L +G G FG V G VA+K L G R + E++ + Sbjct 883 FHNDSL-----IGSGGFGDVYKAILK-----DGSAVAIKKLIHVSGQGDRE-FMAEMETI 931 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHS---IGLAQLLLFAQQ 1006 + H +++ G C+ E+ LV E++ GSL D L P+ + + + A Sbjct 932 GKIKHRNLVPLLGYCKVGDER--LLVYEFMKYGSLEDVLHDPKKAGVKLNWSTRRKIAIG 989 Query 1007 ICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 G+A+LH + H IHRD+ + NVLLD + ++ DFG+A+ + + V + Sbjct 990 SARGLAFLHHNCSPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGT 1049 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 P + PE + ++ DV+S+GV L ELLT + SP L+G + Q LR Sbjct 1050 PG-YVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKRPTDSPDFGDNNLVGWVK-QHAKLR 1107 Query 1124 LTELLERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILKTVH 1173 ++++ + E + E+ +K C + A RPT ++ + K + Sbjct 1108 ISDVFDP-ELMKEDPALEIELLQHLKVAVACLDDRAWRRPTMVQVMAMFKEIQ 1159 >sp|G5ECH7|CDK5_CAEEL Cyclin-dependent-like kinase 5 OS=Caenorhabditis elegans OX=6239 GN=cdk-5 PE=1 SV=1 Length=292 Score = 79.0 bits (193), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 62/205 (30%), Positives = 99/205 (48%), Gaps = 24/205 (12%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957 K+ +GEG +G V + N +GE+VA+K ++ D + S +EI ILR L H Sbjct 6 KMEKIGEGTYGTV----FKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHR 61 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVP------LGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011 ++++ E L LV EY SL Y+ + A+ L+ Q+ G+ Sbjct 62 NVVRLYDVV--HSENKLTLVFEYCDQDLKKFFDSLNGYMDAQT---ARSLML--QLLRGL 114 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-AP 1070 ++ HA H +HRDL +N+L++ + +K+ DFGLA+A + + WY P Sbjct 115 SFCHAHHVLHRDLKPQNLLINTNGTLKLADFGLARAFGVPVRCF----SAEVVTLWYRPP 170 Query 1071 ECLKEYKFYYAS-DVWSFGVTLYEL 1094 + L K Y S D+WS G E+ Sbjct 171 DVLFGAKLYNTSIDMWSAGCIFAEI 195 >sp|Q9SHI2|Y1723_ARATH Leucine-rich repeat receptor-like serine/threonine-protein kinase At1g17230 OS=Arabidopsis thaliana OX=3702 GN=At1g17230 PE=1 SV=2 Length=1101 Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 73/219 (33%), Positives = 98/219 (45%), Gaps = 28/219 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 LG G G V Y G GE++AVK L + G + ++ EI L + H +I+K Sbjct 805 LGRGACGTV----YKAEMSG-GEVIAVKKLNSRGEGASSDNSFRAEISTLGKIRHRNIVK 859 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-------FAQQICEGMAYL 1014 G C Q S L+ EY+ GSL + L R G LL A EG+ YL Sbjct 860 LYGFCYHQ--NSNLLLYEYMSKGSLGEQLQR---GEKNCLLDWNARYRIALGAAEGLCYL 914 Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 H +HRD+ + N+LLD +GDFGLAK + Y + + APE Sbjct 915 HHDCRPQIVHRDIKSNNILLDERFQAHVGDFGLAKLID--LSYSKSMSAVAGSYGYIAPE 972 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 K D++SFGV L EL+T PP + LE Sbjct 973 YAYTMKVTEKCDIYSFGVVLLELITG-----KPPVQPLE 1006 Score = 43.1 bits (100), Expect = 0.021, Method: Compositional matrix adjust. Identities = 43/173 (25%), Positives = 75/173 (43%), Gaps = 20/173 (12%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--K 711 +F S + ++ H ++ ++G C N+++ EY+ G L L+R + + W + Sbjct 841 SFRAEISTLGKIRHRNIVKLYGFCYHQNSNLLLYEYMSKGSLGEQLQRGEKNCLLDWNAR 900 Query 712 MVVAQQLASALSYLENK---NLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGAL 767 +A A L YL + +VH ++ NILL R G KL D L Sbjct 901 YRIALGAAEGLCYLHHDCRPQIVHRDIKSNNILLDERFQAHVGDFGLAKLID-------L 953 Query 768 SREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 S + + + ++APE ++ D + FG LLE+ G+ P+Q Sbjct 954 SYSKSMSAVAGSYGYIAPEY--AYTMKVTEKCDIYSFGVVLLEL-ITGKPPVQ 1003 >sp|Q28948|AAPK2_PIG 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Sus scrofa OX=9823 GN=PRKAA2 PE=2 SV=2 Length=552 Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 73/201 (36%), Positives = 95/201 (47%), Gaps = 22/201 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957 LG G FGKV + + TG VAVK L + RS K+EI L+ H Sbjct 22 LGVGTFGKVKI----GEHQLTGHKVAVKILNRQ---KIRSLDVVGKIKREIQNLKLFRHP 74 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016 HIIK + +VMEYV G L DY+ +H + + QQI + Y H Sbjct 75 HIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE + Sbjct 133 HMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 187 Query 1077 KFYYA--SDVWSFGVTLYELL 1095 + Y D+WS GV LY LL Sbjct 188 RLYAGPEVDIWSCGVILYALL 208 Score = 36.6 bits (83), Expect = 1.7, Method: Compositional matrix adjust. Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 24/262 (9%) Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726 H H+ ++ V + MV EYV G L ++ + G V + QQ+ SA+ Y Sbjct 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKH-GRVEEMEARRLFQQILSAVDYCH 131 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-----WLAP 781 +VH ++ N+LL A K++D GL + + R + AP Sbjct 132 RHMVVHRDLKPENVLLDAQMNA-------KIAD--FGLSNMMSDGEFLRTSCGSPNYAAP 182 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQ 840 E + G + +D W G L + G P P+ + +PE Sbjct 183 EVISGRLYA-GPEVDIWSCGVILYALLC-GTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS 240 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 +ATL L +P +R + + I R+ + +L L P+ P+ D V +K++ Sbjct 241 VATLLMHMLQVDPLKRATIKDI-REHEWFK-QDLPSYLF--PEDPSYDANVIDDEAVKEV 296 Query 901 RDLGEGHFGKV--SLYCYDPTN 920 + E +V SLY DP + Sbjct 297 CEKFECTESEVMNSLYSGDPQD 318 >sp|P54646|AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Homo sapiens OX=9606 GN=PRKAA2 PE=1 SV=2 Length=552 Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 73/201 (36%), Positives = 95/201 (47%), Gaps = 22/201 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957 LG G FGKV + + TG VAVK L + RS K+EI L+ H Sbjct 22 LGVGTFGKVKI----GEHQLTGHKVAVKILNRQ---KIRSLDVVGKIKREIQNLKLFRHP 74 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016 HIIK + +VMEYV G L DY+ +H + + QQI + Y H Sbjct 75 HIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE + Sbjct 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 187 Query 1077 KFYYA--SDVWSFGVTLYELL 1095 + Y D+WS GV LY LL Sbjct 188 RLYAGPEVDIWSCGVILYALL 208 Score = 36.2 bits (82), Expect = 2.3, Method: Compositional matrix adjust. Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 24/262 (9%) Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726 H H+ ++ V + MV EYV G L ++ + G V + QQ+ SA+ Y Sbjct 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKH-GRVEEMEARRLFQQILSAVDYCH 131 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-----WLAP 781 +VH ++ N+LL A K++D GL + + R + AP Sbjct 132 RHMVVHRDLKPENVLLDAHMNA-------KIAD--FGLSNMMSDGEFLRTSCGSPNYAAP 182 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQ 840 E + G + +D W G L + G P P+ + +PE Sbjct 183 EVISGRLYA-GPEVDIWSCGVILYALLC-GTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS 240 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 +ATL L +P +R + + I R+ + +L L P+ P+ D V +K++ Sbjct 241 VATLLMHMLQVDPLKRATIKDI-REHEWFK-QDLPSYLF--PEDPSYDANVIDDEAVKEV 296 Query 901 RDLGEGHFGKV--SLYCYDPTN 920 + E +V SLY DP + Sbjct 297 CEKFECTESEVMNSLYSGDPQD 318 >sp|P34112|CDK1_DICDI Cyclin-dependent kinase 1 OS=Dictyostelium discoideum OX=44689 GN=cdk1 PE=2 SV=1 Length=296 Score = 79.0 bits (193), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 64/202 (32%), Positives = 97/202 (48%), Gaps = 15/202 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +K+ LGEG +GKV Y TG MVA+K ++ + + + EI +L+ + H Sbjct 11 QKLEKLGEGTYGKV----YKAKEKATGRMVALKKIRLEDDGVPSTALR-EISLLKEVPHP 65 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLHA 1016 +++ Q L LV EY+ L+ Y+ QL+ + Q+ +G+AY H Sbjct 66 NVVSLFDVLHCQNR--LYLVFEYLD-QDLKKYMDSVPALCPQLIKSYLYQLLKGLAYSHG 122 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075 +HRDL +N+L+D +K+ DFGLA+AV Y + WY APE L Sbjct 123 HRILHRDLKPQNLLIDRQGALKLADFGLARAVSIPVRVYT----HEIVTLWYRAPEVLLG 178 Query 1076 YKFYYA-SDVWSFGVTLYELLT 1096 K Y D+WS G E+L Sbjct 179 SKSYSVPVDMWSVGCIFGEMLN 200 Score = 36.2 bits (82), Expect = 1.8, Method: Compositional matrix adjust. Identities = 66/309 (21%), Positives = 111/309 (36%), Gaps = 73/309 (24%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +L LG+GT VY+ + + G V LK + Sbjct 12 KLEKLGEGTYGKVYKAKEKATGR------------------------MVALKKIRLEDDG 47 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 + SL+ +V H ++ + V +V EY LD L++ VP Sbjct 48 VPSTALREISLLKEVPHPNVVSLFDVLHCQNRLYLVFEY-----LDQDLKKYMDSVPALC 102 Query 711 KMVVAQ---QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VG 763 ++ QL L+Y ++H ++ +N+L+ R G +KL+D G V Sbjct 103 PQLIKSYLYQLLKGLAYSHGHRILHRDLKPQNLLIDRQGA-------LKLADFGLARAVS 155 Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGEAPLQS- 817 + + + + APE L G+ S S +D W G E+ F G+ + Sbjct 156 IPVRVYTHEIVTLWYRAPEVLL-GSKSYSVPVDMWSVGCIFGEMLNKKPLFSGDCEIDQI 214 Query 818 -----RSPSEKEHFYQRQHRLPE-----------------PSCPQLA-TLTSQCLTYEPT 854 + + + +LPE P C LA L ++ L YEP+ Sbjct 215 FRIFRVLGTPDDSIWPGVTKLPEYVSTFPNWPGQPYNKIFPRCEPLALDLIAKMLQYEPS 274 Query 855 QRPSFRTIL 863 +R S + L Sbjct 275 KRISAKEAL 283 >sp|Q4WVG0|PKCA_ASPFU Protein kinase C OS=Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) OX=330879 GN=pkcA PE=1 SV=1 Length=1106 Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 60/198 (30%), Positives = 91/198 (46%), Gaps = 14/198 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH-----RSGWKQEIDILRTLYHE 957 LG+G+FGKV L T ++ A+K LK + ++ K+ I H Sbjct 787 LGKGNFGKVML----AETKSTKKLYAIKVLKKEFIIENDEVESTKSEKRVFLIANKERHP 842 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 ++ C Q E + VMEY+ G L ++ R GL + +A ++ + Y H Sbjct 843 FLLNLHACF--QTETRVYFVMEYISGGDLMLHIQRGQFGLKRAQFYAAEVLLALKYFHEN 900 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 I+RDL N+LL D +KI D+GL K E Y + APE L + K Sbjct 901 GVIYRDLKLDNILLTLDGHIKIADYGLCK---ENMWYGSTTSTFCGTPEFMAPEILLDKK 957 Query 1078 FYYASDVWSFGVTLYELL 1095 + A D W+FGV +Y++L Sbjct 958 YGRAVDWWAFGVLIYQML 975 >sp|Q9ZRF9|RPK1_ARATH Probable LRR receptor-like serine/threonine-protein kinase RPK1 OS=Arabidopsis thaliana OX=3702 GN=RPK1 PE=1 SV=1 Length=540 Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 73/288 (25%), Positives = 120/288 (42%), Gaps = 21/288 (7%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 Y +G G FG PTN + ++V + D + EI L + Sbjct 260 YFSNSNCIGHGGFGSTYKAEVSPTNVFAVKRLSVGRFQGD------QQFHAEISALEMVR 313 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMA 1012 H +++ G + E + L+ Y+ G+L+D++ S I L A + ++ Sbjct 314 HPNLVMLIGYHASETE--MFLIYNYLSGGNLQDFIKERSKAAIEWKVLHKIALDVARALS 371 Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068 YLH Q +HRD+ N+LLDN+ + DFGL+K + + G + F Y Sbjct 372 YLHEQCSPKVLHRDIKPSNILLDNNYNAYLSDFGLSKLLGTSQSHVTT---GVAGTFGYV 428 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 APE + +DV+S+G+ L EL++ D S S ++ A ++ + Sbjct 429 APEYAMTCRVSEKADVYSYGIVLLELISDKRALDPSFSSHENGFNIVSWAHMMLSQGKAK 488 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 E+ G P EV HL C S RPT + + +LK + Sbjct 489 EVFTTGLWETGPPDDLVEVLHLALKCTVDSLSIRPTMKQAVRLLKRIQ 536 Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust. Identities = 59/248 (24%), Positives = 95/248 (38%), Gaps = 37/248 (15%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV- 713 F+ S + V H +L + G E ++ Y+ G L +++ ER + WK++ Sbjct 302 FHAEISALEMVRHPNLVMLIGYHASETEMFLIYNYLSGGNLQDFIK-ERSKAAIEWKVLH 360 Query 714 -VAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAE----GTSPFIKLSDPGVGLG 765 +A +A ALSYL + ++H ++ NILL A G S + S V G Sbjct 361 KIALDVARALSYLHEQCSPKVLHRDIKPSNILLDNNYNAYLSDFGLSKLLGTSQSHVTTG 420 Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-- 823 ++APE +S D + +G LLE+ D A S S E Sbjct 421 VAGT------FGYVAPEY--AMTCRVSEKADVYSYGIVLLELISDKRALDPSFSSHENGF 472 Query 824 -----EHFYQRQHRL------------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 H Q + P ++ L +C + RP+ + +R L Sbjct 473 NIVSWAHMMLSQGKAKEVFTTGLWETGPPDDLVEVLHLALKCTVDSLSIRPTMKQAVRLL 532 Query 867 TRLQPHNL 874 R+QP L Sbjct 533 KRIQPSRL 540 >sp|Q00536|CDK16_HUMAN Cyclin-dependent kinase 16 OS=Homo sapiens OX=9606 GN=CDK16 PE=1 SV=1 Length=496 Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 60/202 (30%), Positives = 94/202 (47%), Gaps = 15/202 (7%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 K+ LGEG + V Y + T +VA+K ++ + +E+ +L+ L H + Sbjct 167 KLDKLGEGTYATV----YKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHAN 222 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHA 1016 I+ EKSL LV EY+ L+ YL + I + + LF Q+ G+AY H Sbjct 223 IVTLHDII--HTEKSLTLVFEYLD-KDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHR 279 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE--CLK 1074 Q +HRDL +N+L++ +K+ DFGLA+A + Y + WY P L Sbjct 280 QKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTY----SNEVVTLWYRPPDILLG 335 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + D+W G YE+ T Sbjct 336 STDYSTQIDMWGVGCIFYEMAT 357 Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust. Identities = 61/271 (23%), Positives = 106/271 (39%), Gaps = 57/271 (21%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 R ++LS++ F +++ +L LG+GT VY+G+ K+ D Sbjct 150 RRVSLSEIGFGKLET--YIKLDKLGEGTYATVYKGK-----------SKLTDN------- 189 Query 632 DRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 V LK + H + A A E SL+ + H ++ +H + +V EY Sbjct 190 ------LVALKEIRLEHEEGAPCTAIRE-VSLLKDLKHANIVTLHDIIHTEKSLTLVFEY 242 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 ++ L +L + M + QL L+Y + ++H ++ +N+L+ G Sbjct 243 LDKD-LKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERG--- 298 Query 750 GTSPFIKLSDPGVGLGALSREERVERIP-----------WLAPECLPGGANSLSTAMDKW 798 +KL+D G+ R + IP W P + G+ ST +D W Sbjct 299 ----ELKLADFGLA--------RAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMW 346 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 G G E+ G + E+ HF R Sbjct 347 GVGCIFYEMA-TGRPLFPGSTVEEQLHFIFR 376 >sp|A0A0U1RPR8|GUC2D_MOUSE Guanylate cyclase D OS=Mus musculus OX=10090 GN=Gucy2d PE=2 SV=1 Length=1117 Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 75/266 (28%), Positives = 120/266 (45%), Gaps = 25/266 (9%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 GE V +K +A P R + LR + HE++ + G G ++ V+E+ Sbjct 577 GEWVWLKKFEAGVAPDLRPSSLSFLRKLREMRHENVTAFLGLFVGPGVSAM--VLEHCAR 634 Query 984 GSLRDYLPRHSIGL-----AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 GSL D L ++ L A LLL + G+ YLH + + H L +RN ++D ++K Sbjct 635 GSLEDLLQNENLRLDWTFKASLLL---DLIRGLRYLHHRRFPHGRLKSRNCVVDTRFVLK 691 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK-EYKFYYASDVWSFGVTLYELLTH 1097 I D G A+ + E H R + + W APE L+ K + DV+S + L E+LT Sbjct 692 ITDHGYAEFL-ESHCSSR-PQPAPEELLWTAPELLRGPGKATFKGDVFSLAIILQEVLT- 748 Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157 + PP L + + ++ L PD+ P E LM+ CWE Sbjct 749 ----RDPPYCSWGL----SAEEIIRKVASPPPLCRPLVSPDQGPLECIQLMQLCWEEAPD 800 Query 1158 FRPTFENLIPILKTVHEKYQGQAPSV 1183 RP+ + + K+++ QG+ SV Sbjct 801 DRPSLDQIYTQFKSIN---QGKKTSV 823 >sp|Q6ZLP5|CIPKN_ORYSJ CBL-interacting protein kinase 23 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK23 PE=2 SV=1 Length=450 Score = 80.9 bits (198), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 64/205 (31%), Positives = 100/205 (49%), Gaps = 23/205 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEH 958 R LGEG F KV N +GE VA+K L D +H+ + K+EI ++ + H + Sbjct 17 RTLGEGTFAKVKF----ARNADSGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPN 72 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +I+ + + + +VME V G L D + R + + QQ+ + Y H++ Sbjct 73 VIRMHEVMASKTK--IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSR 130 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG------DSPVFWYAPE 1071 HRDL N+LLD +K+ DFGL+ + VREDG +P + APE Sbjct 131 GVYHRDLKPENLLLDASGTLKVSDFGLSALSQQ------VREDGLLHTTCGTPNY-VAPE 183 Query 1072 CLKEYKFYYA-SDVWSFGVTLYELL 1095 + + A +D+WS GV L+ L+ Sbjct 184 VINNKGYDGAKADLWSCGVILFVLM 208 Score = 41.2 bits (95), Expect = 0.052, Method: Compositional matrix adjust. Identities = 61/241 (25%), Positives = 101/241 (42%), Gaps = 30/241 (12%) Query 639 VVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K+LD H + S M + H ++ +H V + +V E V G L Sbjct 39 VAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRMHEVMASKTKIYIVMELVTGGEL 98 Query 696 -DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 D R R A K QQL +A+ Y ++ + H ++ N+LL A GT Sbjct 99 FDKIASRGRLKEDDARKYF--QQLINAVDYCHSRGVYHRDLKPENLLLD----ASGT--- 149 Query 755 IKLSDPGVGLGALSREERVERI--------PWLAPECLPGGANSLSTAMDKWGFGATLLE 806 +K+SD GL ALS++ R + + ++APE + + A D W G L Sbjct 150 LKVSD--FGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKA-DLWSCGVILF- 205 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQ-RPSFRTILRD 865 + G P + S Y++ + + SCP + +++ L + PS R + + Sbjct 206 VLMAGYLPFED---SNLMSLYKKIFK-ADFSCPSWFSTSAKKLIKKILDPNPSTRITIAE 261 Query 866 L 866 L Sbjct 262 L 262 >sp|Q5RD00|AAPK2_PONAB 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Pongo abelii OX=9601 GN=PRKAA2 PE=2 SV=1 Length=552 Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 73/201 (36%), Positives = 95/201 (47%), Gaps = 22/201 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957 LG G FGKV + + TG VAVK L + RS K+EI L+ H Sbjct 22 LGVGTFGKVKI----GEHQLTGHKVAVKILNRQ---KIRSLDVVGKIKREIQNLKLFRHP 74 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016 HIIK + +VMEYV G L DY+ +H + + QQI + Y H Sbjct 75 HIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHR 132 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE + Sbjct 133 HMVVHRDLKPENVLLDAHMNAKIADFGLSNIMSDG-EF--LRTSCGSPNYA-APEVISG- 187 Query 1077 KFYYA--SDVWSFGVTLYELL 1095 + Y D+WS GV LY LL Sbjct 188 RLYAGPEVDIWSCGVILYALL 208 Score = 35.8 bits (81), Expect = 2.6, Method: Compositional matrix adjust. Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 24/262 (9%) Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726 H H+ ++ V + MV EYV G L ++ + G V + QQ+ SA+ Y Sbjct 73 HPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKH-GRVEEMEARRLFQQILSAVDYCH 131 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-----WLAP 781 +VH ++ N+LL A K++D GL + + R + AP Sbjct 132 RHMVVHRDLKPENVLLDAHMNA-------KIAD--FGLSNIMSDGEFLRTSCGSPNYAAP 182 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQ 840 E + G + +D W G L + G P P+ + +PE Sbjct 183 EVISGRLYA-GPEVDIWSCGVILYALLC-GTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS 240 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 +ATL L +P +R + + I R+ + +L L P+ P+ D V +K++ Sbjct 241 VATLLMHMLQVDPLKRATIKDI-REHEWFK-QDLPSYLF--PEDPSYDANVIDDEAVKEV 296 Query 901 RDLGEGHFGKV--SLYCYDPTN 920 + E +V SLY DP + Sbjct 297 CEKFECTESEVMNSLYSGDPQD 318 >sp|Q9C6P3|CDPKX_ARATH Calcium-dependent protein kinase 33 OS=Arabidopsis thaliana OX=3702 GN=CPK33 PE=1 SV=1 Length=521 Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 68/209 (33%), Positives = 103/209 (49%), Gaps = 30/209 (14%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHE- 957 ++LG G FG V+ C T TG+ A K++ K + ++EI I++ L + Sbjct 77 KELGRGQFG-VTYLC---TEKSTGKRFACKSISKKKLVTKGDKEDMRREIQIMQHLSGQP 132 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-------YLPRHSIGLAQLLLFAQQICEG 1010 +I+++KG ED EK++ LVME G L D Y R + + + ++ IC Sbjct 133 NIVEFKGAYED--EKAVNLVMELCAGGELFDRILAKGHYSERAAASVCRQIVNVVNIC-- 188 Query 1011 MAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 H +HRDL N LL D L+K DFGL+ + EG RV +D ++ Sbjct 189 ----HFMGVMHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEG----RVYKDIVGSAYY 240 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096 APE LK ++ D+WS G+ LY LL+ Sbjct 241 VAPEVLKR-RYGKEIDIWSAGIILYILLS 268 >sp|Q54WJ0|STK11_DICDI Serine/threonine-protein kinase stk11 homolog OS=Dictyostelium discoideum OX=44689 GN=lkb1 PE=3 SV=1 Length=586 Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 62/201 (31%), Positives = 104/201 (52%), Gaps = 19/201 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK---ADCGPQHRSGWKQEIDILRTLYHEHI 959 LGEG +GKV D + T + VAVK LK P + +EI+I + L+++HI Sbjct 46 LGEGAYGKVK----DGMDSFTQKRVAVKILKRARLKKIPGGEASVLKEINITKKLHNKHI 101 Query 960 IKYKG--CCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYL 1014 IK E++G+ L +V EYV G+ ++ L P + Q +Q+ E Y+ Sbjct 102 IKLIDHFIIEEKGK--LYIVYEYVGGGTSQNILENAPNGRLPPHQSQFIFRQLIEACEYI 159 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H+Q +HRD+ N+L + ++K+ DFG+A+ + ++ + SP F P L Sbjct 160 HSQKILHRDIKPDNILFTHANVLKLSDFGVAEDSSQLEDFECLSRSYGSPAF--QPPELT 217 Query 1075 EYKFYYAS---DVWSFGVTLY 1092 +++ ++ D+W+ GVTLY Sbjct 218 QFQTTFSPFKIDIWAMGVTLY 238 >sp|P42818|KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6 OS=Arabidopsis thaliana OX=3702 GN=ATPK1 PE=1 SV=1 Length=465 Score = 80.9 bits (198), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 63/201 (31%), Positives = 97/201 (48%), Gaps = 15/201 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHE 957 ++ +G+G FGKV Y T E+ A+K ++ D H K E DIL + H Sbjct 137 MKVVGKGAFGKV----YQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHP 192 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL-LFAQQICEGMAYLHA 1016 I++ K Q + L LV++++ G L L + L ++ +I +++LH Sbjct 193 FIVQLKYSF--QTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHE 250 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075 + +HRDL N+L+D D V + DFGLAK E R + Y APE ++ Sbjct 251 KGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEEN-----TRSNSMCGTTEYMAPEIVRG 305 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 A+D WS G+ LYE+LT Sbjct 306 KGHDKAADWWSVGILLYEMLT 326 Score = 35.0 bits (79), Expect = 4.3, Method: Compositional matrix adjust. Identities = 35/150 (23%), Positives = 62/150 (41%), Gaps = 19/150 (13%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 V ++ SA+S+L K ++H ++ NIL+ T + L+D G+ A EE Sbjct 236 VYTAEIVSAVSHLHEKGIMHRDLKPENILM-------DTDGHVMLTDFGL---AKEFEEN 285 Query 773 VER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 ++APE + G + A D W G L E+ G+ P ++ Sbjct 286 TRSNSMCGTTEYMAPEIVRGKGH--DKAADWWSVGILLYEM-LTGKPPFLGSKGKIQQKI 342 Query 827 YQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 + + +LP+ + + L EP +R Sbjct 343 VKDKIKLPQFLSNEAHAILKGLLQKEPERR 372 >sp|Q0D4B2|CIPKL_ORYSJ CBL-interacting protein kinase 21 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK21 PE=2 SV=2 Length=525 Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 67/206 (33%), Positives = 102/206 (50%), Gaps = 23/206 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEH 958 R LGEGHFGKV L + TG A+K L + K+EI L+ L H + Sbjct 91 RALGEGHFGKVKL----ARHADTGAAFAIKILDRQRILAMKIDEQIKREIATLKLLKHPN 146 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +++ + + + +V+EYV G L D + + + + QQ+ + ++Y H + Sbjct 147 VVRLHEVSASKTK--IYMVLEYVNGGELFDKIALKGKLSEKEGRKLFQQLMDAVSYCHEK 204 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG------DSPVFWYAPE 1071 HRDL NVL+D +K+ DFGL+ A+P+ R+DG SP + APE Sbjct 205 GVYHRDLKPENVLVDAKGNIKVSDFGLS-ALPQNQ-----RKDGLLHTTCGSP-NYIAPE 257 Query 1072 CLKEYKFYYA-SDVWSFGVTLYELLT 1096 L + + SD+WS GV LY +LT Sbjct 258 VLLNRGYDGSLSDIWSCGVILYVMLT 283 Score = 38.9 bits (89), Expect = 0.32, Method: Compositional matrix adjust. Identities = 55/208 (26%), Positives = 87/208 (42%), Gaps = 35/208 (17%) Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPL--DVWLRRERGHVPMAWKMVVAQQLASAL 722 + H ++ +H V + MV EYV G L + L+ G + + QQL A+ Sbjct 142 LKHPNVVRLHEVSASKTKIYMVLEYVNGGELFDKIALK---GKLSEKEGRKLFQQLMDAV 198 Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI------ 776 SY K + H ++ N+L+ A+G IK+SD GL AL + +R + + Sbjct 199 SYCHEKGVYHRDLKPENVLVD----AKGN---IKVSD--FGLSALPQNQRKDGLLHTTCG 249 Query 777 --PWLAPECL--PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR--- 829 ++APE L G SLS D W G +L + G P ++ YQ+ Sbjct 250 SPNYIAPEVLLNRGYDGSLS---DIWSCG-VILYVMLTGNLPFDDQNTVV---LYQKILK 302 Query 830 -QHRLPEPSCPQLATLTSQCLTYEPTQR 856 R+P+ P + + L P R Sbjct 303 GDARIPKWLSPGAQDILRKILDPNPITR 330 >sp|Q9ZR08|Y4230_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At4g03230 OS=Arabidopsis thaliana OX=3702 GN=At4g03230 PE=3 SV=3 Length=852 Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 87/281 (31%), Positives = 131/281 (47%), Gaps = 29/281 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V Y G E +AVK L + C Q +K E+ ++ L H ++++ Sbjct 538 LGQGGFGPV----YKGMFPGDQE-IAVKRL-SRCSGQGLEEFKNEVVLIAKLQHRNLVRL 591 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ------ICEGMAYLHA 1016 G C GE+ L L+ EY+P SL ++ L Q L + + I G+ YLH Sbjct 592 LGYCV-AGEEKL-LLYEYMPHKSLDFFIFDRK--LCQRLDWKMRCNIILGIARGLLYLHQ 647 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRDL N+LLD + KI DFGLA+ + G E + +PE Sbjct 648 DSRLRIIHRDLKTSNILLDEEMNPKISDFGLAR-IFGGSETSANTNRVVGTYGYMSPEYA 706 Query 1074 KEYKFYYASDVWSFGVTLYELLT-HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 E F + SDV+SFGV + E ++ ++ P K L L+G A R ELL++ Sbjct 707 LEGLFSFKSDVFSFGVVVIETISGKRNTGFHEPEKSLSLLGHAWDLWKAERGIELLDQAL 766 Query 1133 RLPRPDKCPCEVYHLMKN----CWETEASFRPTFENLIPIL 1169 + + C E + N C + + + RPT N++ +L Sbjct 767 Q----ESCETEGFLKCLNVGLLCVQEDPNDRPTMSNVVFML 803 Score = 45.8 bits (107), Expect = 0.003, Method: Compositional matrix adjust. Identities = 42/163 (26%), Positives = 74/163 (45%), Gaps = 20/163 (12%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM-- 712 F L++++ H +L + G CV G E +++ EY+ H LD ++ + + WKM Sbjct 573 FKNEVVLIAKLQHRNLVRLLGYCVAGEEKLLLYEYMPHKSLDFFIFDRKLCQRLDWKMRC 632 Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGAL 767 + +A L YL + ++H ++ NIL L E +P K+SD G+ G Sbjct 633 NIILGIARGLLYLHQDSRLRIIHRDLKTSNIL-----LDEEMNP--KISDFGLARIFGGS 685 Query 768 SREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLE 806 R+ +++PE G S + D + FG ++E Sbjct 686 ETSANTNRVVGTYGYMSPEYALEGLFSFKS--DVFSFGVVVIE 726 >sp|Q641K5|NUAK1_MOUSE NUAK family SNF1-like kinase 1 OS=Mus musculus OX=10090 GN=Nuak1 PE=1 SV=1 Length=658 Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 65/229 (28%), Positives = 106/229 (46%), Gaps = 18/229 (8%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDL----GEGHFGKVSLYCYDPTNDGTGEMVAVK 930 A V P P HK LK +L G+G +GKV T +G +VA+K Sbjct 30 ATAAPVEPRKPHGVKRHHHKHNLKHRYELQETLGKGTYGKVKR----ATERFSGRVVAIK 85 Query 931 ALKADCGPQHRS--GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +++ D ++EI+I+ +L H HII E++ + + ++MEY G L D Sbjct 86 SIRKDKIKDELDMVHIRREIEIMSSLNHPHIISIYEVFENKDK--IVIIMEYASKGELYD 143 Query 989 YLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 Y+ R + + F +QI + Y H +HRDL N+LLD++ +KI DFGL+ Sbjct 144 YISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNL 203 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELL 1095 ++ + + + +PE + + D W+ GV LY L+ Sbjct 204 ----YQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLI 248 Score = 37.0 bits (84), Expect = 1.4, Method: Compositional matrix adjust. Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 14/153 (9%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 +MS ++H H+ ++ V + +++ EY G L ++ ER + +Q+ S Sbjct 107 IMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYI-SERRRLSERETRHFFRQIVS 165 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---- 776 A+ Y +VH ++ NILL + IK++D GL L ++++ + Sbjct 166 AVHYCHKNGVVHRDLKLENILL-------DDNCNIKIAD--FGLSNLYQKDKFLQTFCGS 216 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 P A + G +D W G L + + Sbjct 217 PLYASPEIVNGRPYRGPEVDSWALGVLLYTLIY 249 >sp|P13186|KIN2_YEAST Serine/threonine-protein kinase KIN2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=KIN2 PE=1 SV=3 Length=1147 Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 67/233 (29%), Positives = 101/233 (43%), Gaps = 35/233 (15%) Query 892 FHKRYLKK---IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQE 947 FH+R L + +G G GKV L + T + + +A KA QH K E Sbjct 91 FHRRSLGDWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNE 150 Query 948 IDIL-----------------------RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 +IL + LYH HI + C ++ EYV G Sbjct 151 SEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNH--FYMLFEYVSGG 208 Query 985 SLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 L DY+ +H S+ FA+ I + YLHA + +HRDL N+++ + +KI DFG Sbjct 209 QLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFG 268 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELL 1095 L+ +Y + +++ APE LK + D+WSFG+ LY L+ Sbjct 269 LSNIF----DYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLV 317 Score = 38.9 bits (89), Expect = 0.35, Method: Compositional matrix adjust. Identities = 50/211 (24%), Positives = 95/211 (45%), Gaps = 18/211 (9%) Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQL 718 ASL + H H+ + +C M+ EYV G L ++ + G + A+ + Sbjct 174 ASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYII-QHGSLKEHHARKFARGI 232 Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER---VER 775 ASAL YL N+VH ++ NI+++ G IK+ D G+ R++ Sbjct 233 ASALQYLHANNIVHRDLKIENIMISSSG-------EIKIIDFGLSNIFDYRKQLHTFCGS 285 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATL-LEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834 + + APE L + +D W FG L + +C G+ P + S H ++ ++ Sbjct 286 LYFAAPELLKAQPYT-GPEVDIWSFGIVLYVLVC--GKVPFDDEN-SSILHEKIKKGKVD 341 Query 835 EPS--CPQLATLTSQCLTYEPTQRPSFRTIL 863 PS ++ +L ++ + +P +R + + ++ Sbjct 342 YPSHLSIEVISLLTRMIVVDPLRRATLKNVV 372 >sp|Q8BZ25|ANKK1_MOUSE Ankyrin repeat and protein kinase domain-containing protein 1 OS=Mus musculus OX=10090 GN=Ankk1 PE=2 SV=1 Length=745 Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 66/223 (30%), Positives = 105/223 (47%), Gaps = 24/223 (11%) Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEG 1010 + + +HI+ G C+ + L +VME++ GSL LP HS+ L + Sbjct 87 MEKIKFQHIVSIYGVCK----QPLGIVMEFMASGSLEKTLPTHSLCWPLKLRIIHETSLA 142 Query 1011 MAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG-HEYYRVREDGDSPVFW 1067 M +LH+ +H DL N+LLDN+ VKI DFGL+K + + + Y R + + Sbjct 143 MNFLHSIKPPLLHLDLKPGNILLDNNMHVKISDFGLSKWMEQSTQKQYIERSALRGTLSY 202 Query 1068 YAPECLKEYKFYYAS--DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 PE E DV+SF + ++E+LT Q P L ++ I ++R+ Sbjct 203 IPPEMFLENNKAPGPEYDVYSFAIVIWEILT-----QKKPYAGLNMMTI------IIRVA 251 Query 1126 ELLERGERLPRPDKCPCEVY---HLMKNCWETEASFRPTFENL 1165 + R D+ P EV+ +LMK CW+ + RP F N+ Sbjct 252 AGM-RPSLQDVSDEWPEEVHQMVNLMKRCWDQDPKKRPCFLNV 293 Score = 35.8 bits (81), Expect = 3.4, Method: Compositional matrix adjust. Identities = 50/251 (20%), Positives = 96/251 (38%), Gaps = 35/251 (14%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 +E A M ++ H+ ++GVC + P I V E++ G L+ L P+ +++ Sbjct 80 LFEEAVKMEKIKFQHIVSIYGVC-KQPLGI-VMEFMASGSLEKTLPTHSLCWPLKLRIIH 137 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREER 772 LA + L+H ++ NILL + +K+SD G+ + ++++ Sbjct 138 ETSLAMNFLHSIKPPLLHLDLKPGNILL-------DNNMHVKISDFGLSKWMEQSTQKQY 190 Query 773 VER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--------FDGEAPLQSR 818 +ER + ++ PE + D + F + EI + + Sbjct 191 IERSALRGTLSYIPPEMFLENNKAPGPEYDVYSFAIVIWEILTQKKPYAGLNMMTIIIRV 250 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + PE Q+ L +C +P +RP F + + D+L Sbjct 251 AAGMRPSLQDVSDEWPE-EVHQMVNLMKRCWDQDPKKRPCFLNVAVE---------TDML 300 Query 879 TVNPDSPASDP 889 SP +DP Sbjct 301 LSLFQSPMTDP 311 >sp|Q9SR87|LRK61_ARATH Probable L-type lectin-domain containing receptor kinase VI.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK61 PE=2 SV=1 Length=693 Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 68/210 (32%), Positives = 107/210 (51%), Gaps = 19/210 (9%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 + K+ +G G FG V Y + ++ G +AVK + ++ R + EI+ L L Sbjct 366 KKFKESEIIGTGGFGIV--YRGNLSSSGP---IAVKKITSNSLQGVRE-FMAEIESLGRL 419 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLF--AQQIC 1008 H++++ +G C+ + E L L+ +Y+P GSL L R+ I L + F + I Sbjct 420 GHKNLVNLQGWCKHKNE--LLLIYDYIPNGSLDSLLYQTPRRNGIVLPWDVRFEIIKGIA 477 Query 1009 EGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 G+ YLH Q +HRD+ NVL+D D K+GDFGLA+ G + G + Sbjct 478 SGLLYLHEEWEQIVVHRDVKPSNVLIDEDMNAKLGDFGLARLYERGTLTQTTKIVG--TL 535 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 + APE + K ASDV++FGV L E++ Sbjct 536 GYMAPELTRNGKGSTASDVFAFGVLLLEIV 565 Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 58/238 (24%), Positives = 97/238 (41%), Gaps = 48/238 (20%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL----RRERGHVPMAWKMVVAQQ 717 + ++ H +L + G C E +++ +Y+ +G LD L RR +P + + + Sbjct 416 LGRLGHKNLVNLQGWCKHKNELLLIYDYIPNGSLDSLLYQTPRRNGIVLPWDVRFEIIKG 475 Query 718 LASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGALSRE 770 +AS L YL + +VH +V N+L+ A KL D G+ G L++ Sbjct 476 IASGLLYLHEEWEQIVVHRDVKPSNVLIDEDMNA-------KLGDFGLARLYERGTLTQT 528 Query 771 ER-VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 + V + ++APE G STA D + FG LLEI + P+ E+F+ Sbjct 529 TKIVGTLGYMAPELTRNGKG--STASDVFAFGVLLLEI-------VCGNKPTNAENFFLA 579 Query 830 QHRLPEPSCPQLATLTSQ--------------------CLTYEPTQRPSFRTILRDLT 867 + + + + Q C +P RPS R +LR L Sbjct 580 DWVMEFHTNGGILCVVDQNLGSSFNGREAKLALVVGLLCCHQKPKFRPSMRMVLRYLN 637 >sp|Q13233|M3K1_HUMAN Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens OX=9606 GN=MAP3K1 PE=1 SV=4 Length=1512 Score = 82.4 bits (202), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 64/243 (26%), Positives = 119/243 (49%), Gaps = 23/243 (9%) Query 868 RLQPHNLADVLTVNPDSPASDP--TVFHKRYLK-----KIRDLGEGHFGKVSLYCYDPTN 920 +LQ N D++ + D+P + P T + Y + K + +G G F CY + Sbjct 1207 QLQVENGEDIIIIQQDTPETLPGHTKAKQPYREDTEWLKGQQIGLGAFSS----CYQAQD 1262 Query 921 DGTGEMVAVKAL---KADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGC-CEDQGEKSL 974 GTG ++AVK + + Q ++EI ++ L H +II+ G CE + + Sbjct 1263 VGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCE---KSNY 1319 Query 975 QLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033 L +E++ GS+ L ++ +++ + +Q+ G++YLH IHRD+ N+L+D+ Sbjct 1320 NLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDS 1379 Query 1034 D-RLVKIGDFG-LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091 + ++I DFG A+ +G + + + APE L+ ++ + DVWS G + Sbjct 1380 TGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAI 1439 Query 1092 YEL 1094 E+ Sbjct 1440 IEM 1442 Score = 49.3 bits (116), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 52/227 (23%), Positives = 95/227 (42%), Gaps = 16/227 (7%) Query 648 HHDIALAFYETASLMSQVSHTHLAFVHG-VCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 ++ A E +MS ++H ++ + G C + N+ + E++ G + L + G Sbjct 1284 QEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFI-EWMAGGSV-AHLLSKYGAF 1341 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF---IKLSDPGVG 763 + + +QL LSYL ++H +V G N+L+ G + F +L+ G G Sbjct 1342 KESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTG 1401 Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE- 822 G + + + I ++APE L G + D W G ++E+ + P + S Sbjct 1402 AGEF-QGQLLGTIAFMAPEVLRG--QQYGRSCDVWSVGCAIIEMAC-AKPPWNAEKHSNH 1457 Query 823 -----KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 K +P P L + +CL +P RP R +L+ Sbjct 1458 LALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLK 1504 >sp|A3B529|CIPKS_ORYSJ CBL-interacting protein kinase 28 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK28 PE=2 SV=2 Length=435 Score = 80.5 bits (197), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 71/221 (32%), Positives = 108/221 (49%), Gaps = 31/221 (14%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD----CGPQHRSGWK 945 +V +RY+ R LG+G FGKV Y N +G+ VA+K + + G + K Sbjct 5 SVLMERYVIG-RQLGQGTFGKV----YYARNLSSGQSVAIKMIDKEKILKVGLMEQ--IK 57 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA 1004 +EI I+R + H ++++ E KS + +EY G L + R + + Sbjct 58 REISIMRLVRHPNVLQ---LFEVMATKSNIYFALEYAKGGELFHKMARAKLNEESARNYF 114 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG--- 1061 QQ+ M Y H++ HRDL N+LLD + +K+ DFGL+ A+ E R+DG Sbjct 115 QQLISAMDYCHSRGVYHRDLKPENLLLDENETLKVSDFGLS-ALAESR-----RQDGLLH 168 Query 1062 ---DSPVFWYAPECLKEYKFYYAS--DVWSFGVTLYELLTH 1097 +P + APE L K Y S DVWS GV L+ L+ + Sbjct 169 TACGTPAY-VAPEVLSR-KGYSGSKADVWSCGVILFVLVAN 207 Score = 41.6 bits (96), Expect = 0.038, Method: Compositional matrix adjust. Identities = 72/313 (23%), Positives = 119/313 (38%), Gaps = 49/313 (16%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LGQGT VY R SG KM D++ ++ + +++ +I Sbjct 16 QLGQGTFGKVYYAR--NLSSGQSVAIKMIDKEKILK-----------VGLMEQIKREI-- 60 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 S+M V H ++ + V EY + G L + R + + A Sbjct 61 ------SIMRLVRHPNVLQLFEVMATKSNIYFALEYAKGGELFHKMARAKLNEESARNYF 114 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 QQL SA+ Y ++ + H ++ N+LL + +K+SD GL AL+ R Sbjct 115 --QQLISAMDYCHSRGVYHRDLKPENLLL-------DENETLKVSD--FGLSALAESRRQ 163 Query 774 ERI--------PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-E 824 + + ++APE L S S A D W G L + P R+ + Sbjct 164 DGLLHTACGTPAYVAPEVLSRKGYSGSKA-DVWSCGVILF-VLVANYLPFHDRNIIQMYR 221 Query 825 HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP------HNLADVL 878 + ++R P +L L L +P+ R S I R +P +N Sbjct 222 KIAKAEYRCPRHFSAELKELLYGILDPDPSTRMSISRIKRSAWYRKPIAISALNNETGKK 281 Query 879 TVNPDSPASDPTV 891 + ++P S PT+ Sbjct 282 SCTSEAPFSGPTI 294 >sp|Q69Q47|CIPKO_ORYSJ CBL-interacting protein kinase 24 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK24 PE=1 SV=1 Length=453 Score = 80.9 bits (198), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 60/199 (30%), Positives = 98/199 (49%), Gaps = 13/199 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTLYHEH 958 R +G+G F KV + TG VA+K L D HR K+EI I++ + H + Sbjct 22 RTIGQGTFAKVKF----AVDADTGAAVAMKVLDKDTILNHRMLHQIKREISIMKIVRHPN 77 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQ 1017 I++ G+ + +++E + G L D + R + + + QQ+ + + Y H++ Sbjct 78 IVRLNEVL--AGKTKIYIILELITGGELFDKIARQGKLRENEARKYFQQLIDAINYCHSK 135 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 HRDL N+LLD+ +K+ DFGL+ +G + +P + APE L Sbjct 136 GVYHRDLKPENLLLDSRGNLKVSDFGLSTLAQKGVGL--LHTTCGTP-NYVAPEVLSNNG 192 Query 1078 FY-YASDVWSFGVTLYELL 1095 + A+DVWS GV LY L+ Sbjct 193 YDGSAADVWSCGVILYVLM 211 Score = 38.9 bits (89), Expect = 0.31, Method: Compositional matrix adjust. Identities = 55/232 (24%), Positives = 89/232 (38%), Gaps = 12/232 (5%) Query 639 VVLKVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +KVLD +H + S+M V H ++ ++ V + ++ E + G L Sbjct 44 VAMKVLDKDTILNHRMLHQIKREISIMKIVRHPNIVRLNEVLAGKTKIYIILELITGGEL 103 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPF 754 + R+ G + QQL A++Y +K + H ++ N+LL +R L Sbjct 104 FDKIARQ-GKLRENEARKYFQQLIDAINYCHSKGVYHRDLKPENLLLDSRGNLKVSDFGL 162 Query 755 IKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 L+ GVGL ++APE L S A D W G +L + G P Sbjct 163 STLAQKGVGL----LHTTCGTPNYVAPEVLSNNGYDGSAA-DVWSCG-VILYVLMAGYLP 216 Query 815 LQSRS-PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + P+ + Q P P +L + L P R + I D Sbjct 217 FEEDDLPTLYDKITAGQFSCPYWFSPGATSLIHRILDPNPKTRITIEQIRED 268 >sp|Q9SYS3|CRK40_ARATH Cysteine-rich receptor-like protein kinase 40 OS=Arabidopsis thaliana OX=3702 GN=CRK40 PE=2 SV=1 Length=654 Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 64/201 (32%), Positives = 97/201 (48%), Gaps = 16/201 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V + G+ VAVK L G Q +K E+ +L L H++++K Sbjct 354 LGQGGFGTVYKGTFP-----NGQEVAVKRLTKGSG-QGDMEFKNEVSLLTRLQHKNLVKL 407 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017 G C ++G++ + LV E+VP SL ++ R + + I G+ YLH Sbjct 408 LGFC-NEGDEEI-LVYEFVPNSSLDHFIFDEDKRSLLTWEVRFRIIEGIARGLLYLHEDS 465 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 IHRDL A N+LLD + K+ DFG A+ + + + APE L Sbjct 466 QLKIIHRDLKASNILLDAEMNPKVADFGTARLFDSDETRAETKRIAGTRGY-MAPEYLNH 524 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 + SDV+SFGV L E+++ Sbjct 525 GQISAKSDVYSFGVMLLEMIS 545 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 56/186 (30%), Positives = 87/186 (47%), Gaps = 22/186 (12%) Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 GQE V +K L + F SL++++ H +L + G C G E I+V E+V + Sbjct 369 NGQE--VAVKRLTKGSGQGDMEFKNEVSLLTRLQHKNLVKLLGFCNEGDEEILVYEFVPN 426 Query 693 GPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGL 747 LD ++ E + W + + + +A L YL + ++H ++ NILL Sbjct 427 SSLDHFIFDEDKRSLLTWEVRFRIIEGIARGLLYLHEDSQLKIIHRDLKASNILLD---- 482 Query 748 AEGTSPFIKLSDPGVGLGALSREERVE--RIP----WLAPECLPGGANSLSTAMDKWGFG 801 AE +P K++D G S E R E RI ++APE L G +S D + FG Sbjct 483 AE-MNP--KVADFGTARLFDSDETRAETKRIAGTRGYMAPEYLNHG--QISAKSDVYSFG 537 Query 802 ATLLEI 807 LLE+ Sbjct 538 VMLLEM 543 >sp|Q39192|SRK2D_ARATH Serine/threonine-protein kinase SRK2D OS=Arabidopsis thaliana OX=3702 GN=SRK2D PE=1 SV=1 Length=362 Score = 79.7 bits (195), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 77/229 (34%), Positives = 111/229 (48%), Gaps = 24/229 (10%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935 D T +P P P + ++D+G G+FG L T+ T E+VAVK ++ Sbjct 2 DPATNSPIMPIDLPIMHDSDRYDFVKDIGSGNFGVARLM----TDRVTKELVAVKYIER- 56 Query 936 CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PR 992 G + ++EI R+L H +I+++K L +VMEY G L + + R Sbjct 57 -GEKIDENVQREIINHRSLRHPNIVRFKEVI--LTPSHLAIVMEYAAGGELYERICNAGR 113 Query 993 HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVP 1049 S A+ F QQ+ G++Y HA HRDL N LLD RL KI DFG +K+ Sbjct 114 FSEDEARF--FFQQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRL-KICDFGYSKS-- 168 Query 1050 EGHEYYRVREDGDSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELLT 1096 + + + +P + APE L +EY A DVWS GVTLY +L Sbjct 169 -SVLHSQPKSTVGTPA-YIAPEILLRQEYDGKLA-DVWSCGVTLYVMLV 214 >sp|P25323|MYLKA_DICDI Myosin light chain kinase A OS=Dictyostelium discoideum OX=44689 GN=mlkA PE=1 SV=2 Length=295 Score = 79.0 bits (193), Expect = 2e-14, Method: Composition-based stats. Identities = 67/199 (34%), Positives = 94/199 (47%), Gaps = 15/199 (8%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHII 960 +LG G F V Y N T + A+K + K++ G + K E+DIL+ + H +II Sbjct 13 ELGRGAFSIV----YLGENKQTKQRYAIKVINKSELGKDYEKNLKMEVDILKKVNHPNII 68 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 K D EK L LVME V G L D + + S A ++I + YLH + Sbjct 69 ALKELF-DTPEK-LYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGLNI 126 Query 1020 IHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL N+LL +N V I DFGL+K + + V + + APE L Sbjct 127 VHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQT----LVMQTACGTPSYVAPEVLNAT 182 Query 1077 KFYYASDVWSFGVTLYELL 1095 + D+WS GV Y LL Sbjct 183 GYDKEVDMWSIGVITYILL 201 >sp|Q6UD73|LYK3_MEDTR LysM domain receptor-like kinase 3 OS=Medicago truncatula OX=3880 GN=LYK3 PE=1 SV=1 Length=620 Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 81/286 (28%), Positives = 126/286 (44%), Gaps = 34/286 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FG V + GE A+K + Q S + E+ +L ++H ++++ Sbjct 328 IGQGGFGAVYY------AELRGEKTAIKKMDV----QASSEFLCELKVLTHVHHLNLVRL 377 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017 G C E SL LV E++ G+L YL H IG L + A G+ Y+H Sbjct 378 IGYCV---EGSLFLVYEHIDNGNLGQYL--HGIGTEPLPWSSRVQIALDSARGLEYIHEH 432 Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 YIHRD+ + N+L+D + K+ DFGL K + G+ R G F Y P Sbjct 433 TVPVYIHRDVKSANILIDKNLRGKVADFGLTKLIEVGNSTLHTRLVG---TFGYMPPEYA 489 Query 1075 EY-KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +Y DV++FGV LYEL+T ++ E G+ Q L + LE + Sbjct 490 QYGDVSPKIDVYAFGVVLYELITAKNAVLKTGESVAESKGLVQLFEEALHRMDPLEGLRK 549 Query 1134 L--PR-----PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 L PR P ++ L + C RP+ +++ L T+ Sbjct 550 LVDPRLKENYPIDSVLKMAQLGRACTRDNPLLRPSMRSIVVALMTL 595 >sp|Q9S9M2|WAKLD_ARATH Wall-associated receptor kinase-like 4 OS=Arabidopsis thaliana OX=3702 GN=WAKL4 PE=2 SV=2 Length=761 Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 76/252 (30%), Positives = 114/252 (45%), Gaps = 23/252 (9%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 G +VAVK KA + E+ +L + H +I+K GCC + + LV E+VP Sbjct 446 GRIVAVKRSKA-MDEDKVEEFINEVVVLAQINHRNIVKLLGCCLET--EVPVLVYEFVPN 502 Query 984 GSL----RDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI---HRDLAARNVLLDNDRL 1036 G L RD + + L A +I ++YLH+ HRD+ N+LLD Sbjct 503 GDLCKRLRDECDDYIMTWEVRLHIAIEIAGALSYLHSAASFPIYHRDIKTTNILLDEKYQ 562 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA-PECLKEYKFYYASDVWSFGVTLYELL 1095 VK+ DFG +++V + + G F Y PE + KF SDV+SFGV L EL+ Sbjct 563 VKVSDFGTSRSVTIDQTHLTTQVAG---TFGYVDPEYFQSSKFTDKSDVYSFGVVLVELI 619 Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE-RGERLPRPDKCPCE----VYHLMKN 1150 T + S ++ E G A + ++ L+ ER+ D+C + V L K Sbjct 620 TGKNPSSRVQSE--ENRGFAAHFVAAVKENRFLDIVDERI--KDECNLDQVMAVAKLAKR 675 Query 1151 CWETEASFRPTF 1162 C + RP Sbjct 676 CLNRKGKKRPNM 687 Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 72/305 (24%), Positives = 124/305 (41%), Gaps = 65/305 (21%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LGQG + VY+G L V GR V +K D Sbjct 430 LGQGGQGTVYKGML-------------------VDGR------IVAVKRSKAMDEDKVEE 464 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F +++Q++H ++ + G C+ ++V E+V +G L LR E M W ++ Sbjct 465 FINEVVVLAQINHRNIVKLLGCCLETEVPVLVYEFVPNGDLCKRLRDECDDYIMTWEVRL 524 Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 +A ++A ALSYL + + H ++ NILL +K+SD G Sbjct 525 HIAIEIAGALSYLHSAASFPIYHRDIKTTNILLDE-------KYQVKVSDFGTSRSVTID 577 Query 770 EERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + + ++ PE ++ + D + FG L+E+ G+ P SR SE+ Sbjct 578 QTHLTTQVAGTFGYVDPEYFQ--SSKFTDKSDVYSFGVVLVEL-ITGKNP-SSRVQSEEN 633 Query 825 -----HFYQ--RQHRL---------PEPSCPQ---LATLTSQCLTYEPTQRPSFRTILRD 865 HF +++R E + Q +A L +CL + +RP+ R + + Sbjct 634 RGFAAHFVAAVKENRFLDIVDERIKDECNLDQVMAVAKLAKRCLNRKGKKRPNMREVSVE 693 Query 866 LTRLQ 870 L R++ Sbjct 694 LERIR 698 >sp|Q54RB2|CDK11_DICDI Cyclin-dependent kinase 11 OS=Dictyostelium discoideum OX=44689 GN=cdk11 PE=3 SV=1 Length=358 Score = 79.7 bits (195), Expect = 2e-14, Method: Composition-based stats. Identities = 62/207 (30%), Positives = 106/207 (51%), Gaps = 18/207 (9%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILR 952 KK+ + EG FG V YC + T E+VA+K +K + + R G +EI +L Sbjct 52 FKKLYTINEGAFGVV--YC--AQDKETEEIVALKKIKME---REREGIPITSVREIKVLM 104 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQICEG 1010 L H++I++ K + S+ + ME++ L L + + + + +++ QQ+ G Sbjct 105 ELKHDNIVQIKEIVLGKNINSIFMAMEFIDHDLRGLMEVIKKPFLP-SEIKTLIQQLLNG 163 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 ++Y+H IHRDL N+L N ++KI DFGLA+ E + G +++ AP Sbjct 164 VSYMHDNWVIHRDLKTANLLYTNKGVLKIADFGLAR---EYGSPLKPLSKGVVTLWYRAP 220 Query 1071 ECLKEYKFYY-ASDVWSFGVTLYELLT 1096 E L + + Y A D+WS G E+++ Sbjct 221 ELLLDTEIYTPAIDIWSVGCIFAEIIS 247 >sp|P0DL10|TD1_MAIZE Leucine-rich repeat receptor-like kinase protein THICK TASSEL DWARF1 OS=Zea mays OX=4577 GN=TD1 PE=2 SV=1 Length=996 Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 81/288 (28%), Positives = 122/288 (42%), Gaps = 24/288 (8%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 LK+ +G+G G V Y G E+ + + CG H G+ E+ L + H Sbjct 703 LKEDNIIGKGGAGIV----YHGVTRGGAELAIKRLVGRGCG-DHDRGFTAEVTTLGRIRH 757 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---LLLFAQQICEGMAY 1013 +I++ G ++ E +L L+ EY+P GSL + L G A + G+ Y Sbjct 758 RNIVRLLGFVSNR-EANL-LLYEYMPNGSLGEMLHGGKGGHLGWEARARVAAEAARGLCY 815 Query 1014 LH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 LH A IHRD+ + N+LLD+ + DFGLAK + G + AP Sbjct 816 LHHDCAPRIIHRDVKSNNILLDSAFEAHVADFGLAKFLGGGGATSECMSAIAGSYGYIAP 875 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ------GQMTVLRL 1124 E + SDV+SFGV L EL+T + P F + + I Sbjct 876 EYAYTLRVDEKSDVYSFGVVLLELIT----GRRPVGSFGDGVDIVHWVRKVTADAAAAEE 931 Query 1125 TELLERGERL-PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 LL RL P P ++Y + C E ++ RPT ++ +L T Sbjct 932 PVLLVADRRLAPEPVPLLADLYRVAMACVEEASTARPTMREVVHMLST 979 >sp|Q9LZU4|CRK4_ARATH Cysteine-rich receptor-like protein kinase 4 OS=Arabidopsis thaliana OX=3702 GN=CRK4 PE=2 SV=1 Length=676 Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 83/287 (29%), Positives = 127/287 (44%), Gaps = 35/287 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+V + +G VAVK L G R + E+ ++ L H ++++ Sbjct 357 LGQGGFGEVYKGIFP-----SGVQVAVKRLSKTSGQGERE-FANEVIVVAKLQHRNLVRL 410 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ------ICEGMAYLHA 1016 G C ++ E+ L V E+VP SL DY S + LL + ++ I G+ YLH Sbjct 411 LGFCLERDERIL--VYEFVPNKSL-DYFIFDST-MQSLLDWTRRYKIIGGIARGILYLHQ 466 Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRDL A N+LL +D KI DFG+A+ R + + +PE Sbjct 467 DSRLTIIHRDLKAGNILLGDDMNAKIADFGMARIFGMDQTEANTRRIVGT-YGYMSPEYA 525 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +F SDV+SFGV + E++ S + ++ G + G + V L G Sbjct 526 MYGQFSMKSDVYSFGVLVLEII-----SGKKNSNVYQMDGTSAGNL-VTYTWRLWSNGSP 579 Query 1134 LPRPDKCPCEVY---------HLMKNCWETEASFRPTFENLIPILKT 1171 L D + Y H+ C + EA RPT ++ +L T Sbjct 580 LELVDPSFRDNYRINEVSRCIHIALLCVQEEAEDRPTMSAIVQMLTT 626 Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust. Identities = 61/269 (23%), Positives = 110/269 (41%), Gaps = 55/269 (20%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 ++V +K L + F +++++ H +L + G C+ E I+V E+V + LD Sbjct 374 VQVAVKRLSKTSGQGEREFANEVIVVAKLQHRNLVRLLGFCLERDERILVYEFVPNKSLD 433 Query 697 VWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGT 751 ++ + W + + +A + YL + ++H ++ NILL G Sbjct 434 YFIFDSTMQSLLDWTRRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNILL-------GD 486 Query 752 SPFIKLSDPGVG--LGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLL 805 K++D G+ G E RI +++PE G S+ + D + FG +L Sbjct 487 DMNAKIADFGMARIFGMDQTEANTRRIVGTYGYMSPEYAMYGQFSMKS--DVYSFGVLVL 544 Query 806 EIC----------FDGE----------------APLQSRSPSEKEHFYQRQHRLPEPS-C 838 EI DG +PL+ PS ++++ R+ E S C Sbjct 545 EIISGKKNSNVYQMDGTSAGNLVTYTWRLWSNGSPLELVDPSFRDNY-----RINEVSRC 599 Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLT 867 +A L C+ E RP+ I++ LT Sbjct 600 IHIALL---CVQEEAEDRPTMSAIVQMLT 625 >sp|Q9ZVR7|PSKR1_ARATH Phytosulfokine receptor 1 OS=Arabidopsis thaliana OX=3702 GN=PSKR1 PE=1 SV=4 Length=1008 Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 61/183 (33%), Positives = 92/183 (50%), Gaps = 17/183 (9%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 G+ VA+K L DCG R ++ E++ L H +++ +G C + ++ L+ Y+ Sbjct 756 GKKVAIKKLSGDCGQIERE-FEAEVETLSRAQHPNLVLLRGFCFYKNDR--LLIYSYMEN 812 Query 984 GSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDR 1035 GSL +L + G A L L AQ +G+ YLH H +HRD+ + N+LLD + Sbjct 813 GSLDYWLHERNDGPALLKWKTRLRIAQGAAKGLLYLHEGCDPHILHRDIKSSNILLDENF 872 Query 1036 LVKIGDFGLAKAVP--EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 + DFGLA+ + E H V D + + PE + Y DV+SFGV L E Sbjct 873 NSHLADFGLARLMSPYETH----VSTDLVGTLGYIPPEYGQASVATYKGDVYSFGVVLLE 928 Query 1094 LLT 1096 LLT Sbjct 929 LLT 931 Score = 57.4 bits (137), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 52/188 (28%), Positives = 82/188 (44%), Gaps = 28/188 (15%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K L I F +S+ H +L + G C + +++ Y+E+G LD Sbjct 758 KVAIKKLSGDCGQIEREFEAEVETLSRAQHPNLVLLRGFCFYKNDRLLIYSYMENGSLDY 817 Query 698 WL-RRERGHVPMAWK--MVVAQQLASALSYLE---NKNLVHGNVCGRNIL--------LA 743 WL R G + WK + +AQ A L YL + +++H ++ NIL LA Sbjct 818 WLHERNDGPALLKWKTRLRIAQGAAKGLLYLHEGCDPHILHRDIKSSNILLDENFNSHLA 877 Query 744 RLGLAEGTSPF-IKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 GLA SP+ +S VG + ++ PE G A+ + D + FG Sbjct 878 DFGLARLMSPYETHVSTDLVG-----------TLGYIPPEY--GQASVATYKGDVYSFGV 924 Query 803 TLLEICFD 810 LLE+ D Sbjct 925 VLLELLTD 932 >sp|P07527|WEE1_SCHPO Mitosis inhibitor protein kinase wee1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=wee1 PE=1 SV=1 Length=877 Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 64/206 (31%), Positives = 101/206 (49%), Gaps = 22/206 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLY 955 + + LG G F +V DP AVK LK GP+ R+ QE+ I R L Sbjct 566 FRNVTLLGSGEFSEV-FQVEDPVEKTLK--YAVKKLKVKFSGPKERNRLLQEVSIQRALK 622 Query 956 -HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ-----QICE 1009 H+HI++ E G L + +E GSL +L L++L F ++ Sbjct 623 GHDHIVELMDSWEHGG--FLYMQVELCENGSLDRFLEEQG-QLSRLDEFRVWKILVEVAL 679 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFW 1067 G+ ++H ++Y+H DL NV++ + +KIGDFG+A VP G E +GD + Sbjct 680 GLQFIHHKNYVHLDLKPANVMITFEGTLKIGDFGMASVWPVPRGME-----REGD--CEY 732 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYE 1093 APE L + + +D++S G+T++E Sbjct 733 IAPEVLANHLYDKPADIFSLGITVFE 758 Score = 34.7 bits (78), Expect = 8.1, Method: Compositional matrix adjust. Identities = 39/135 (29%), Positives = 63/135 (47%), Gaps = 27/135 (20%) Query 685 MVTEYVEHGPLDVWLRRERGHVPM-----AWKMVVAQQLASALSYLENKNLVHGNVCGRN 739 M E E+G LD +L E+G + WK++V ++A L ++ +KN VH ++ N Sbjct 642 MQVELCENGSLDRFLE-EQGQLSRLDEFRVWKILV--EVALGLQFIHHKNYVHLDLKPAN 698 Query 740 ILLARLGLAEGTSPFIKLSDPGVGL-----GALSREERVERIPWLAPECLPGGANSL-ST 793 +++ EGT +K+ D G+ + RE E ++APE L AN L Sbjct 699 VMIT----FEGT---LKIGDFGMASVWPVPRGMEREGDCE---YIAPEVL---ANHLYDK 745 Query 794 AMDKWGFGATLLEIC 808 D + G T+ E Sbjct 746 PADIFSLGITVFEAA 760 >sp|P13863|CDK1_CHICK Cyclin-dependent kinase 1 OS=Gallus gallus OX=9031 GN=CDK1 PE=1 SV=1 Length=303 Score = 79.0 bits (193), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 63/216 (29%), Positives = 108/216 (50%), Gaps = 27/216 (13%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957 KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L+H Sbjct 6 KIEKIGEGTYGVV----YKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELHHP 61 Query 958 HIIKYKGCCED--QGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGM 1011 +I+ C +D + L L+ E++ + L+ YL + +++ + QI +G+ Sbjct 62 NIV----CLQDVLMQDARLYLIFEFLSM-DLKKYLDTIPSGQYLDRSRVKSYLYQILQGI 116 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-AP 1070 + H++ +HRDL +N+L+D+ ++K+ DFGLA+A Y + WY +P Sbjct 117 VFCHSRRVLHRDLKPQNLLIDDKGVIKLADFGLARAFGIPVRVYT----HEVVTLWYRSP 172 Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLT-----HCDS 1100 E L Y D+WS G EL T H DS Sbjct 173 EVLLGSALYSTPVDIWSIGTIFAELATKKPLFHGDS 208 >sp|Q9H1R3|MYLK2_HUMAN Myosin light chain kinase 2, skeletal/cardiac muscle OS=Homo sapiens OX=9606 GN=MYLK2 PE=1 SV=3 Length=596 Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 60/198 (30%), Positives = 99/198 (50%), Gaps = 15/198 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V C + TG +A K +K P+ + EI+++ L H ++I+ Sbjct 291 LGGGKFGAV-CTCME---KATGLKLAAKVIKKQT-PKDKEMVLLEIEVMNQLNHRNLIQL 345 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYI 1020 E E + L MEY+ G L + + L ++ ++F +QIC+G+ ++H + Sbjct 346 YAAIETPHE--IVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVL 403 Query 1021 HRDLAARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 H DL N+L N LVKI DFGLA+ + +++ + +P F +PE + + Sbjct 404 HLDLKPENILCVNTTGHLVKIIDFGLARRY---NPNEKLKVNFGTPEF-LSPEVVNYDQI 459 Query 1079 YYASDVWSFGVTLYELLT 1096 +D+WS GV Y LL+ Sbjct 460 SDKTDMWSMGVITYMLLS 477 Score = 36.2 bits (82), Expect = 2.1, Method: Compositional matrix adjust. Identities = 37/169 (22%), Positives = 70/169 (41%), Gaps = 21/169 (12%) Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 V+K P ++ L E +M+Q++H +L ++ E ++ EY+E G L + Sbjct 315 VIKKQTPKDKEMVLLEIE---VMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERI 371 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 E H+ MV +Q+ + ++ ++H ++ NIL T +K+ D Sbjct 372 VDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNT-----TGHLVKIID 426 Query 760 PGVGLGALSREERVERIP-------WLAPECLPGGANSLSTAMDKWGFG 801 G R E++ +L+PE + + +S D W G Sbjct 427 ----FGLARRYNPNEKLKVNFGTPEFLSPEVV--NYDQISDKTDMWSMG 469 >sp|Q924I2|M4K3_RAT Mitogen-activated protein kinase kinase kinase kinase 3 OS=Rattus norvegicus OX=10116 GN=Map4k3 PE=1 SV=2 Length=873 Score = 81.6 bits (200), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 56/199 (28%), Positives = 102/199 (51%), Gaps = 14/199 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I+ +G G +G V Y N TGE+ A+K +K + G + + +QEI +++ H +I Sbjct 19 IQRIGSGTYGDV----YKARNVNTGELAAIKVIKLEPG-EDFAVVQQEIIMMKDCKHANI 73 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 + Y G + + L + ME+ GSL+D Y + Q+ +++ +G+ YLH++ Sbjct 74 VAYFGSYLRRDK--LWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKG 131 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL---KE 1075 +HRD+ N+LL ++ VK+ DFG++ + R+ +W APE ++ Sbjct 132 KMHRDIKGANILLTDNGHVKLADFGVSAQITAT---IAKRKSFIGTPYWMAPEVAAVERK 188 Query 1076 YKFYYASDVWSFGVTLYEL 1094 + D+W+ G+T EL Sbjct 189 GGYNQLCDLWAVGITAIEL 207 Score = 41.2 bits (95), Expect = 0.072, Method: Compositional matrix adjust. Identities = 73/322 (23%), Positives = 122/322 (38%), Gaps = 59/322 (18%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 R Q++ + +G GT +VY+ R + G+ + + Sbjct 10 RNPQEDFELIQRIGSGTYGDVYKAR----------------------NVNTGELAAIKVI 47 Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRR 701 L+P D A+ E +M H ++ G +R + + E+ G L D++ Sbjct 48 KLEPGE-DFAVVQQEII-MMKDCKHANIVAYFGSYLRRDKLWICMEFCGGGSLQDIY--H 103 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 G + V+++ L YL +K +H ++ G NILL G +KL+D G Sbjct 104 VTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNG-------HVKLADFG 156 Query 762 VG---LGALSREERVERIP-WLAPECLP----GGANSLSTAMDKWGFGATLLEIC----- 808 V +++ + P W+APE GG N L D W G T +E+ Sbjct 157 VSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLC---DLWAVGITAIELAELQPP 213 Query 809 -FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD-- 865 FD P+++ K +F + + LT P +RP+ +L+ Sbjct 214 MFDLH-PMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPF 272 Query 866 ----LTRLQPHNLADVLTVNPD 883 LTR L D + NPD Sbjct 273 VTQPLTRSLAIELLDKVN-NPD 293 >sp|Q91604|STK11_XENLA Serine/threonine-protein kinase stk11 OS=Xenopus laevis OX=8355 GN=stk11 PE=1 SV=1 Length=432 Score = 80.5 bits (197), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 60/198 (30%), Positives = 95/198 (48%), Gaps = 6/198 (3%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG +GKV D + +K K P + K+EI +LR L H ++I+ Sbjct 58 LGEGSYGKVK-EMLDSDTLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHRNVIQL 116 Query 963 KGCCEDQGEKSLQLVMEYVPLG--SLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 ++ ++ + +VMEY G + D + + Q + Q+ +G+ YLH+Q + Sbjct 117 VDVLYNEEKQKMYMVMEYCVCGMQEMLDSVQDKHFPVFQAHGYFCQLIDGLEYLHSQGIV 176 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 H+D+ N+LL D +KI D G+A+A+ E R SP F PE + Sbjct 177 HKDIKPGNLLLTTDGTLKISDLGVAEALHPFAEGDTCRTSQGSPAFQ-PPEIANGLDTFS 235 Query 1080 -YASDVWSFGVTLYELLT 1096 + D+WS GVTLY + T Sbjct 236 GFKVDIWSAGVTLYNITT 253 Score = 48.1 bits (113), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 53/213 (25%), Positives = 86/213 (40%), Gaps = 21/213 (10%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL-- 742 MV EY G ++ + H P+ QL L YL ++ +VH ++ N+LL Sbjct 130 MVMEYCVCGMQEMLDSVQDKHFPVFQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTT 189 Query 743 ------ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLST-AM 795 + LG+AE PF + G+ P P + G ++ S + Sbjct 190 DGTLKISDLGVAEALHPFAEGDTCRTSQGS----------PAFQPPEIANGLDTFSGFKV 239 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854 D W G TL I G P + + + E+ + + +PE P L+ L L Y+P Sbjct 240 DIWSAGVTLYNIT-TGLYPFEGDNIYKLFENIGKGDYSIPEECGPLLSDLLRGMLEYDPA 298 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 +R S + I + + H D + P SP + Sbjct 299 KRFSIQQIRQHNWFRKKHPHMDPIVPIPPSPET 331 >sp|Q9LFV3|CRLK2_ARATH Calcium/calmodulin-regulated receptor-like kinase 2 OS=Arabidopsis thaliana OX=3702 GN=CRLK2 PE=2 SV=1 Length=436 Score = 80.5 bits (197), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 62/220 (28%), Positives = 99/220 (45%), Gaps = 23/220 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V GE+ A K ++ R ++ E+ +L L+H +++ Sbjct 120 LGQGSFGPVYKAVMP-----NGELAAAKVHGSNSSQGDRE-FQTEVSLLGRLHHRNLVNL 173 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 G C D+ + L+ E++ GSL + L + + L A I G+ YLH Sbjct 174 TGYCVDKSHR--MLIYEFMSNGSLENLLYGGEGMQVLNWEERLQIALDISHGIEYLHEGA 231 Query 1019 Y---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 IHRDL + N+LLD+ K+ DFGL+K + R+ + P + Sbjct 232 VPPVIHRDLKSANILLDHSMRAKVADFGLSKEMV----LDRMTSGLKGTHGYMDPTYIST 287 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 K+ SD++SFGV + EL+T P +E I +A Sbjct 288 NKYTMKSDIYSFGVIILELITAI----HPQQNLMEYINLA 323 Score = 42.4 bits (98), Expect = 0.023, Method: Compositional matrix adjust. Identities = 50/240 (21%), Positives = 100/240 (42%), Gaps = 39/240 (16%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F SL+ ++ H +L + G CV +++ E++ +G L+ L G + W ++ Sbjct 155 FQTEVSLLGRLHHRNLVNLTGYCVDKSHRMLIYEFMSNGSLENLLYGGEGMQVLNWEERL 214 Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 +A ++ + YL ++H ++ NILL S K++D G LS+ Sbjct 215 QIALDISHGIEYLHEGAVPPVIHRDLKSANILLDH-------SMRAKVADFG-----LSK 262 Query 770 EERVERIP--------WLAPECLPGGANSLSTAMDKWGFGATLLEIC--------FDGEA 813 E ++R+ ++ P + N + D + FG +LE+ Sbjct 263 EMVLDRMTSGLKGTHGYMDPTYI--STNKYTMKSDIYSFGVIILELITAIHPQQNLMEYI 320 Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQ---LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 L S SP + Q + S + LA + ++C+ P +RPS + + + +++ Sbjct 321 NLASMSPDGIDEILD-QKLVGNASIEEVRLLAKIANRCVHKTPRKRPSIGEVTQFILKIK 379 >sp|P54645|AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Rattus norvegicus OX=10116 GN=Prkaa1 PE=1 SV=2 Length=559 Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 72/201 (36%), Positives = 98/201 (49%), Gaps = 22/201 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957 LG G FGKV + ++ TG VAVK L + RS ++EI L+ H Sbjct 33 LGVGTFGKVKV----GKHELTGHKVAVKILNRQ---KIRSLDVVGKIRREIQNLKLFRHP 85 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016 HIIK + + +VMEYV G L DY+ ++ + + QQI G+ Y H Sbjct 86 HIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 143 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE + Sbjct 144 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 198 Query 1077 KFYYA--SDVWSFGVTLYELL 1095 + Y D+WS GV LY LL Sbjct 199 RLYAGPEVDIWSSGVILYALL 219 >sp|O42632|KPC1_COCHE Protein kinase C-like OS=Cochliobolus heterostrophus OX=5016 GN=PKC1 PE=3 SV=1 Length=1174 Score = 82.0 bits (201), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 58/198 (29%), Positives = 91/198 (46%), Gaps = 14/198 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957 LG+G+FGKV L T ++ A+K LK + ++ K+ I H Sbjct 855 LGKGNFGKVML----AETKTTKQLYAIKVLKKEFIIENDEVESTRSEKRVFLIANKERHP 910 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 ++ C Q E + VMEY+ G L ++ R G + +A ++C + Y H Sbjct 911 FLLNLHACF--QTETRVYFVMEYISGGDLMLHIQRGQFGTKRAQFYAAEVCLALKYFHEN 968 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 I+RDL N++L D +K+ D+GL K E Y + APE L + K Sbjct 969 GVIYRDLKLDNIMLTLDGHIKVADYGLCK---EEMWYGSTTSTFCGTPEFMAPEILLDKK 1025 Query 1078 FYYASDVWSFGVTLYELL 1095 + A D W+FGV +Y++L Sbjct 1026 YGRAVDWWAFGVLIYQML 1043 >sp|Q38772|CDC2A_ANTMA Cell division control protein 2 homolog A OS=Antirrhinum majus OX=4151 GN=CDC2A PE=2 SV=2 Length=294 Score = 78.6 bits (192), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 64/208 (31%), Positives = 101/208 (49%), Gaps = 20/208 (10%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYH 956 +K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ + H Sbjct 5 EKVEKIGEGTYGVV----YKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR--DYLPRHSIGLAQLLLFAQQICEGMAYL 1014 +I++ + EK L LV EY+ L + D P S + +F QI G+AY Sbjct 61 GNIVRLQDVV--HSEKRLYLVFEYLDLDLKKHMDSCPEFSQDPRLVKMFLYQILRGIAYC 118 Query 1015 HAQHYIHRDLAARNVLLD-NDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070 H+ +HRDL +N+L+D +K+ DFGLA+A +P + V WY AP Sbjct 119 HSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIPVRTFTHEV------VTLWYRAP 172 Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTH 1097 E L + Y DVWS G E++ Sbjct 173 EILLGSRHYSTPVDVWSVGCIFAEMVNQ 200 >sp|Q9FJ55|CIPKJ_ARATH CBL-interacting serine/threonine-protein kinase 19 OS=Arabidopsis thaliana OX=3702 GN=CIPK19 PE=1 SV=1 Length=483 Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 69/207 (33%), Positives = 103/207 (50%), Gaps = 26/207 (13%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYH 956 R LG G F KV Y N +GE VA+K + D +SG K+EI ILR + H Sbjct 32 RLLGHGTFAKV----YLARNAQSGESVAIKVI--DKEKVLKSGLIAHIKREISILRRVRH 85 Query 957 EHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH 1015 +I++ E KS + VMEYV G L + + + + + QQ+ +++ H Sbjct 86 PNIVQ---LFEVMATKSKIYFVMEYVKGGELFNKVAKGRLKEEMARKYFQQLISAVSFCH 142 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WYAP 1070 + HRDL N+LLD + +K+ DFGL+ AV + ++R+DG F + AP Sbjct 143 FRGVYHRDLKPENLLLDENGNLKVSDFGLS-AVSD-----QIRQDGLFHTFCGTPAYVAP 196 Query 1071 ECLKEYKFYYAS-DVWSFGVTLYELLT 1096 E L + A D+WS GV L+ L+ Sbjct 197 EVLARKGYDGAKVDIWSCGVILFVLMA 223 Score = 40.8 bits (94), Expect = 0.077, Method: Compositional matrix adjust. Identities = 52/213 (24%), Positives = 90/213 (42%), Gaps = 22/213 (10%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S++ +V H ++ + V + V EYV+ G L + + R MA K QQL Sbjct 78 SILRRVRHPNIVQLFEVMATKSKIYFVMEYVKGGELFNKVAKGRLKEEMARKYF--QQLI 135 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776 SA+S+ + + H ++ N+LL G +K+SD GL A+S + R + + Sbjct 136 SAVSFCHFRGVYHRDLKPENLLLDENG-------NLKVSD--FGLSAVSDQIRQDGLFHT 186 Query 777 -----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP-SEKEHFYQRQ 830 ++APE L +D W G L + G P R+ + + Y+ Sbjct 187 FCGTPAYVAPEVLARKGYD-GAKVDIWSCGVILF-VLMAGFLPFHDRNVMAMYKKIYRGD 244 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 R P ++ L + L +P +R + I+ Sbjct 245 FRCPRWFPVEINRLLIRMLETKPERRFTMPDIM 277 >sp|Q5GIG6|TNI3K_MOUSE Serine/threonine-protein kinase TNNI3K OS=Mus musculus OX=10090 GN=Tnni3k PE=2 SV=4 Length=834 Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 66/229 (29%), Positives = 112/229 (49%), Gaps = 18/229 (8%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 ADVL + + P+ + +I +G G FGKV ++VA+K +A Sbjct 442 ADVLLLRAELPSRFHLQLSEIEFHEI--IGSGSFGKVY------KGRCRNKIVAIKRYRA 493 Query 935 D--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-- 990 + C + +E+ IL L H ++++ G C D + +V +Y+ GSL L Sbjct 494 NTYCSKSDVDMFCREVSILCQLNHPCVVQFVGACLDDPSQ-FAIVTQYISGGSLFSLLHE 552 Query 991 PRHSIGLAQLLLFAQQICEGMAYLHA--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + + L L+ A + +GM YLH+ Q IHRDL + N+LL D + DFG ++ + Sbjct 553 QKRILDLQSKLIIAVDVAKGMEYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFL 612 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLT 1096 E ++ G+ + W APE + ++ +DV+S+ + L+ELLT Sbjct 613 QSLDEDNMTKQPGN--LRWMAPEVFTQCTRYTIKADVFSYALCLWELLT 659 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 72/328 (22%), Positives = 127/328 (39%), Gaps = 67/328 (20%) Query 557 ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616 E ++++++R S L LS++ FH + +G G+ VY+GR R Sbjct 440 EKADVLLLRAELPSRFHLQLSEIEFHEI----------IGSGSFGKVYKGRCR------- 482 Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676 + R R S D+ + F S++ Q++H + G Sbjct 483 -------NKIVAIKRYRANTY--------CSKSDVDM-FCREVSILCQLNHPCVVQFVGA 526 Query 677 CVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN--KNLVHG 733 C+ P +VT+Y+ G L L ++ + + K+++A +A + YL + + ++H Sbjct 527 CLDDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHSLTQPIIHR 586 Query 734 NVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALSREERVERIP----WLAPECLP 785 ++ NILL G A G S F++ D E+ + + P W+APE Sbjct 587 DLNSHNILLYEDGHAVVADFGESRFLQSLD----------EDNMTKQPGNLRWMAPEVFT 636 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH-------RLPEPSC 838 + D + + L E+ GE P P+ H +P+P Sbjct 637 -QCTRYTIKADVFSYALCLWEL-LTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPIS 694 Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDL 866 L + C P RP F ++R L Sbjct 695 SLLMRGWNAC----PEGRPEFSEVVRKL 718 >sp|Q9ZWC8|BRL1_ARATH Serine/threonine-protein kinase BRI1-like 1 OS=Arabidopsis thaliana OX=3702 GN=BRL1 PE=1 SV=1 Length=1166 Score = 82.0 bits (201), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 84/286 (29%), Positives = 128/286 (45%), Gaps = 33/286 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG+V G +VA+K L G R + E++ + + H +++ Sbjct 865 VGSGGFGEVY-----KAQLRDGSVVAIKKLIRITGQGDRE-FMAEMETIGKIKHRNLVPL 918 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-------FAQQICEGMAYLH 1015 G C+ GE+ L LV EY+ GSL L S + L A G+A+LH Sbjct 919 LGYCK-VGEERL-LVYEYMKWGSLETVLHEKSSKKGGIYLNWAARKKIAIGAARGLAFLH 976 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 H IHRD+ + NVLLD D ++ DFG+A+ V + V +P + PE Sbjct 977 HSCIPHIIHRDMKSSNVLLDEDFEARVSDFGMARLVSALDTHLSVSTLAGTPGY-VPPEY 1035 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLE---LIGIAQGQMTVLRLTEL 1127 + ++ DV+S+GV L ELL S + P P +F E L+G A+ R E+ Sbjct 1036 YQSFRCTAKGDVYSYGVILLELL----SGKKPIDPGEFGEDNNLVGWAKQLYREKRGAEI 1091 Query 1128 LERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170 L+ L E++H +K C + RPT L+ + K Sbjct 1092 LD--PELVTDKSGDVELFHYLKIASQCLDDRPFKRPTMIQLMAMFK 1135 Score = 38.9 bits (89), Expect = 0.42, Method: Compositional matrix adjust. Identities = 55/248 (22%), Positives = 100/248 (40%), Gaps = 55/248 (22%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---RRERGHVPMAW- 710 F + ++ H +L + G C G E ++V EY++ G L+ L ++G + + W Sbjct 900 FMAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKWGSLETVLHEKSSKKGGIYLNWA 959 Query 711 -KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--L 764 + +A A L++L + +++H ++ N+LL A ++SD G+ + Sbjct 960 ARKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDEDFEA-------RVSDFGMARLV 1012 Query 765 GALSREERVERIP----WLAPE------CLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 AL V + ++ PE C G D + +G LLE+ G+ P Sbjct 1013 SALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKG--------DVYSYGVILLEL-LSGKKP 1063 Query 815 LQSRSPSEKEHFY------QRQHRLPEPSCPQLAT-------------LTSQCLTYEPTQ 855 + E + R+ R E P+L T + SQCL P + Sbjct 1064 IDPGEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELFHYLKIASQCLDDRPFK 1123 Query 856 RPSFRTIL 863 RP+ ++ Sbjct 1124 RPTMIQLM 1131 >sp|Q8VDF3|DAPK2_MOUSE Death-associated protein kinase 2 OS=Mus musculus OX=10090 GN=Dapk2 PE=1 SV=1 Length=370 Score = 79.7 bits (195), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 62/205 (30%), Positives = 100/205 (49%), Gaps = 20/205 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-----WKQEIDILRTLYH 956 +LG G F V C + + TG A K +K R G ++E+ ILR + H Sbjct 28 ELGSGQFAIVK-KCREKS---TGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVLH 83 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLH 1015 +II E++ + + L++E V G L D+L + S+ + F +QI +G+ YLH Sbjct 84 PNIITLHDVYENRTD--VVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLH 141 Query 1016 AQHYIHRDLAARNVLLDNDRL----VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 + H DL N++L + + +K+ DFGLA + +G E+ + +P F APE Sbjct 142 TKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNI---FGTPEF-VAPE 197 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 + +D+WS GV Y LL+ Sbjct 198 IVNYEPLGLEADMWSIGVITYILLS 222 Score = 35.4 bits (80), Expect = 3.4, Method: Compositional matrix adjust. Identities = 42/171 (25%), Positives = 71/171 (42%), Gaps = 18/171 (11%) Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQ 717 S++ QV H ++ +H V + +++ E V G L D ++E A + +Q Sbjct 75 VSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFI--KQ 132 Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE--- 774 + ++YL K + H ++ NI+L + P IKL D G+ A E+ VE Sbjct 133 ILDGVNYLHTKKIAHFDLKPENIMLLDKNIP---IPHIKLIDFGL---AHEIEDGVEFKN 186 Query 775 ---RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 ++APE + L D W G + I G +P + E Sbjct 187 IFGTPEFVAPEIV--NYEPLGLEADMWSIGV-ITYILLSGASPFLGDTKQE 234 >sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4 Length=559 Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 72/201 (36%), Positives = 98/201 (49%), Gaps = 22/201 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957 LG G FGKV + ++ TG VAVK L + RS ++EI L+ H Sbjct 33 LGVGTFGKVKV----GKHELTGHKVAVKILNRQ---KIRSLDVVGKIRREIQNLKLFRHP 85 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016 HIIK + + +VMEYV G L DY+ ++ + + QQI G+ Y H Sbjct 86 HIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 143 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE + Sbjct 144 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 198 Query 1077 KFYYA--SDVWSFGVTLYELL 1095 + Y D+WS GV LY LL Sbjct 199 RLYAGPEVDIWSSGVILYALL 219 >sp|O35280|CHK1_MOUSE Serine/threonine-protein kinase Chk1 OS=Mus musculus OX=10090 GN=Chek1 PE=1 SV=2 Length=476 Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 68/200 (34%), Positives = 98/200 (49%), Gaps = 13/200 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 ++ LGEG +G+V L N T E VAVK + K+EI I + L HE++ Sbjct 12 VQTLGEGAYGEVQL----AVNRITEEAVAVKIVDMKRAIDCPENIKKEICINKMLSHENV 67 Query 960 IKYKGCCEDQGEKSLQ-LVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHA 1016 +K+ G + E +Q L +EY G L D + IG+ + F Q+ G+ YLH Sbjct 68 VKFYG---HRREGHIQYLFLEYCSGGELFDRI-EPDIGMPEQDAQRFFHQLMAGVVYLHG 123 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 HRD+ N+LLD +KI DFGLA V + R+ + + APE LK Sbjct 124 IGITHRDIKPENLLLDERDNLKISDFGLA-TVFRHNNRERLLNKMCGTLPYVAPELLKRK 182 Query 1077 KFYYA-SDVWSFGVTLYELL 1095 +F+ DVWS G+ L +L Sbjct 183 EFHAEPVDVWSCGIVLTAML 202 >sp|F4I1N8|ATG1T_ARATH Serine/threonine-protein kinase ATG1t OS=Arabidopsis thaliana OX=3702 GN=At1g49180 PE=2 SV=1 Length=408 Score = 80.1 bits (196), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 57/178 (32%), Positives = 90/178 (51%), Gaps = 11/178 (6%) Query 923 TGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 TGE +K + R E++ L ++ H +II+ +D + L +V+EY Sbjct 29 TGEEAVMKCFDLSKLNRNLRDCLNNELEFLSSVDHPNIIRLLHVSQD--DDFLVMVLEYC 86 Query 982 PLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLHAQHYIHRDLAARNVLLD---NDRLV 1037 G+L Y+ R+ + F +QI G+ +H H IHRDL N+L+D +D ++ Sbjct 87 DGGTLSSYIQRYGRVEEDIAKRFMKQIGAGLEIIHDNHIIHRDLKPENILIDGSGDDLVL 146 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 KI DF LA+ + G V SP F+ APE L+ ++ +D+WS G L+ELL Sbjct 147 KIADFSLARKLHPGKYLETV---CGSP-FYMAPEVLQFQRYNEKADMWSVGAILFELL 200 >sp|Q5EG47|AAPK1_MOUSE 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Mus musculus OX=10090 GN=Prkaa1 PE=1 SV=2 Length=559 Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 72/201 (36%), Positives = 98/201 (49%), Gaps = 22/201 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957 LG G FGKV + ++ TG VAVK L + RS ++EI L+ H Sbjct 33 LGVGTFGKVKV----GKHELTGHKVAVKILNRQ---KIRSLDVVGKIRREIQNLKLFRHP 85 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016 HIIK + + +VMEYV G L DY+ ++ + + QQI G+ Y H Sbjct 86 HIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 143 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE + Sbjct 144 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 198 Query 1077 KFYYA--SDVWSFGVTLYELL 1095 + Y D+WS GV LY LL Sbjct 199 RLYAGPEVDIWSSGVILYALL 219 >sp|Q5JLQ9|CIPKU_ORYSJ CBL-interacting protein kinase 30 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK30 PE=2 SV=1 Length=476 Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 75/227 (33%), Positives = 110/227 (48%), Gaps = 32/227 (14%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 ++ + D V RY K R LG G F KV Y TGE VA+K D RS Sbjct 4 ETTSQDSQVIMGRY-KLGRLLGRGTFAKV----YKAYKLATGEAVAIKVF--DKEAVQRS 56 Query 943 GW----KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSI 995 G K+E+D++R ++H H+I+ + + VMEY G L L PR Sbjct 57 GTVEQVKREVDVMRRVHHRHVIRLHEVMATRSR--IYFVMEYASGGELFTRLSRSPRFPE 114 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 +A+ + QQ+ + + H++ HRDL N+LLD +K+ DFGL+ A+ G Sbjct 115 PVARR--YFQQLITAVEFCHSRGVYHRDLKPENLLLDARGDLKVTDFGLS-ALDGG---- 167 Query 1056 RVREDG------DSPVFWYAPECLKEYKFYYA-SDVWSFGVTLYELL 1095 +R DG +P + APE L + + A +D+WS GV L+ LL Sbjct 168 -LRGDGLLHTTCGTPAY-VAPEVLLKRGYDGAKADIWSCGVILFVLL 212 >sp|P51952|CDK7_RAT Cyclin-dependent kinase 7 (Fragment) OS=Rattus norvegicus OX=10116 GN=Cdk7 PE=1 SV=2 Length=329 Score = 79.0 bits (193), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 69/230 (30%), Positives = 109/230 (47%), Gaps = 26/230 (11%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ----EIDILRT 953 +K+ LGEG F V Y + T ++VA+K +K + + G + EI +L+ Sbjct 5 EKLDFLGEGQFATV----YKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQE 60 Query 954 LYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEG 1010 L H +II G + G KS + LV +++ L + +S+ L + + + +G Sbjct 61 LSHPNII---GLLDAFGHKSNISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQG 116 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-A 1069 + YLH +HRDL N+LLD + ++K+ DFGLAK+ + Y + WY A Sbjct 117 LEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNWAYTHQ----VVTRWYRA 172 Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIG 1113 PE L + Y D+W+ G L ELL DS T+ E +G Sbjct 173 PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLG 222 >sp|P10665|KS6AA_XENLA Ribosomal protein S6 kinase 2 alpha OS=Xenopus laevis OX=8355 GN=rps6ka PE=1 SV=1 Length=733 Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 57/199 (29%), Positives = 105/199 (53%), Gaps = 8/199 (4%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEH 958 ++ LG+G FGKV L T ++ A+K LK A + R K E DIL ++H Sbjct 65 LKVLGQGSFGKVFL-VRKITPPDANQLYAMKVLKKATLKVRDRVRTKMERDILADVHHPF 123 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ-LLLFAQQICEGMAYLHAQ 1017 +++ + +G+ L L+++++ G L L + + + + + ++ G+ +LH+ Sbjct 124 VVRLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSL 181 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 I+RDL N+LLD + +K+ DFGL+K E ++ + V + APE + Sbjct 182 GIIYRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKKAYSFCGTVEYMAPEVVNRQG 238 Query 1078 FYYASDVWSFGVTLYELLT 1096 +++D WS+GV ++E+LT Sbjct 239 HSHSADWWSYGVLMFEMLT 257 Score = 59.7 bits (143), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 57/195 (29%), Positives = 90/195 (46%), Gaps = 32/195 (16%) Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKS 973 C + GT AVK + + + +EI+ILR H +II K ++ S Sbjct 430 CKRCVHKGTNMEYAVKVID-----KTKRDPSEEIEILRRYGQHPNIIALKDVYKEGN--S 482 Query 974 LQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030 + +V E + G L D + R S A +LF +C+ + LH+Q +HRDL N+L Sbjct 483 IYVVTELMRGGELLDRILRQKFFSEREASSVLFT--VCKTVENLHSQGVVHRDLKPSNIL 540 Query 1031 LDND----RLVKIGDFGLAKAVPEGHEYYRVREDGD---SPVF---WYAPECLKEYKFYY 1080 ++ ++I DFG AK ++R D +P + + APE LK + Sbjct 541 YVDESGDPESIRICDFGFAK---------QLRADNGLLMTPCYTANFVAPEVLKRQGYDE 591 Query 1081 ASDVWSFGVTLYELL 1095 D+WS G+ LY +L Sbjct 592 GCDIWSLGILLYTML 606 >sp|Q7TQP6|TNI3K_RAT Serine/threonine-protein kinase TNNI3K OS=Rattus norvegicus OX=10116 GN=Tnni3k PE=2 SV=3 Length=835 Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 66/229 (29%), Positives = 112/229 (49%), Gaps = 18/229 (8%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 ADVL + + P+ + +I +G G FGKV ++VA+K +A Sbjct 443 ADVLLLRAELPSRFHLQLSEIEFHEI--IGSGSFGKVY------KGRCRNKIVAIKRYRA 494 Query 935 D--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-- 990 + C + +E+ IL L H ++++ G C D + +V +Y+ GSL L Sbjct 495 NTYCSKSDVDMFCREVSILCQLNHPCVVQFVGACLDDPSQ-FAIVTQYISGGSLFSLLHE 553 Query 991 PRHSIGLAQLLLFAQQICEGMAYLHA--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + + L L+ A + +GM YLH+ Q IHRDL + N+LL D + DFG ++ + Sbjct 554 QKRILDLQSKLIIAVDVAKGMEYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFL 613 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLT 1096 E ++ G+ + W APE + ++ +DV+S+ + L+ELLT Sbjct 614 QSLDEDNMTKQPGN--LRWMAPEVFTQCTRYTIKADVFSYSLCLWELLT 660 Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 71/328 (22%), Positives = 126/328 (38%), Gaps = 67/328 (20%) Query 557 ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616 E ++++++R S L LS++ FH + +G G+ VY+GR R Sbjct 441 EKADVLLLRAELPSRFHLQLSEIEFHEI----------IGSGSFGKVYKGRCR------- 483 Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676 + R R S D+ + F S++ Q++H + G Sbjct 484 -------NKIVAIKRYRANTY--------CSKSDVDM-FCREVSILCQLNHPCVVQFVGA 527 Query 677 CVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN--KNLVHG 733 C+ P +VT+Y+ G L L ++ + + K+++A +A + YL + + ++H Sbjct 528 CLDDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHSLTQPIIHR 587 Query 734 NVCGRNILLARLGLAE----GTSPFIKLSDPGVGLGALSREERVERIP----WLAPECLP 785 ++ NILL G A G S F++ D E+ + + P W+APE Sbjct 588 DLNSHNILLYEDGHAVVADFGESRFLQSLD----------EDNMTKQPGNLRWMAPEVFT 637 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH-------RLPEPSC 838 + D + + L E+ GE P P+ H +P+P Sbjct 638 -QCTRYTIKADVFSYSLCLWEL-LTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPIS 695 Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDL 866 L + C P RP F ++ L Sbjct 696 SLLIRGWNAC----PEGRPEFSEVVSKL 719 >sp|O80939|LRK41_ARATH L-type lectin-domain containing receptor kinase IV.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK41 PE=2 SV=1 Length=675 Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 67/201 (33%), Positives = 98/201 (49%), Gaps = 21/201 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---EIDILRTLYHEHI 959 LG G FG V Y GT +AVK + + R G K+ EI + + H ++ Sbjct 353 LGTGGFGSV----YKGVMPGTKLEIAVKRVSHES----RQGMKEFVAEIVSIGRMSHRNL 404 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA 1016 + G C +GE L LV +Y+P GSL YL P ++ Q + + G+ YLH Sbjct 405 VPLLGYCRRRGE--LLLVYDYMPNGSLDKYLYNTPEVTLNWKQRIKVILGVASGLFYLHE 462 Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 Q IHRD+ A NVLLD + ++GDFGLA+ G + G + + APE Sbjct 463 EWEQVVIHRDVKASNVLLDGELNGRLGDFGLARLYDHGSDPQTTHVVG--TLGYLAPEHT 520 Query 1074 KEYKFYYASDVWSFGVTLYEL 1094 + + A+DV++FG L E+ Sbjct 521 RTGRATMATDVFAFGAFLLEV 541 Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 51/185 (28%), Positives = 82/185 (44%), Gaps = 20/185 (11%) Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 G +L + +K + F + ++SH +L + G C R E ++V +Y+ +G Sbjct 368 GTKLEIAVKRVSHESRQGMKEFVAEIVSIGRMSHRNLVPLLGYCRRRGELLLVYDYMPNG 427 Query 694 PLDVWLRRERGHVPMAWK--MVVAQQLASALSYLE---NKNLVHGNVCGRNILL-----A 743 LD +L V + WK + V +AS L YL + ++H +V N+LL Sbjct 428 SLDKYLYNTP-EVTLNWKQRIKVILGVASGLFYLHEEWEQVVIHRDVKASNVLLDGELNG 486 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 RLG + SDP V + +LAPE G +++T D + FGA Sbjct 487 RLGDFGLARLYDHGSDP-------QTTHVVGTLGYLAPEHTRTGRATMAT--DVFAFGAF 537 Query 804 LLEIC 808 LLE+ Sbjct 538 LLEVA 542 >sp|Q9SNA3|Y3463_ARATH Putative receptor-like protein kinase At3g46340 OS=Arabidopsis thaliana OX=3702 GN=At3g46340 PE=1 SV=1 Length=889 Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 61/204 (30%), Positives = 103/204 (50%), Gaps = 15/204 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LGEG FG V Y +G+ + VAVK L + Q +K E+++L ++H +++ Sbjct 589 RPLGEGGFGVV----YHGDINGSSQQVAVKLL-SQSSTQGYKEFKAEVELLLRVHHINLV 643 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQL---LLFAQQICEGMAYLHA 1016 G C+++ L L+ EY+ L+ +L +H + + L A G+ YLH Sbjct 644 SLVGYCDERDH--LALIYEYMSNKDLKHHLSGKHGGSVLKWNTRLQIAVDAALGLEYLHI 701 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +HRD+ + N+LLD+ K+ DFGL+++ G E +P + PE Sbjct 702 GCRPSMVHRDVKSTNILLDDQFTAKMADFGLSRSFQLGDESQVSTVVAGTPGY-LDPEYY 760 Query 1074 KEYKFYYASDVWSFGVTLYELLTH 1097 + + SDV+SFG+ L E++T+ Sbjct 761 RTGRLAEMSDVYSFGIVLLEIITN 784 Score = 41.6 bits (96), Expect = 0.055, Method: Compositional matrix adjust. Identities = 50/189 (26%), Positives = 77/189 (41%), Gaps = 20/189 (11%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G G +V +K+L S F L+ +V H +L + G C ++ EY Sbjct 602 GDINGSSQQVAVKLLSQSSTQGYKEFKAEVELLLRVHHINLVSLVGYCDERDHLALIYEY 661 Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLAR 744 + + L L + G + W ++ +A A L YL ++VH +V NILL Sbjct 662 MSNKDLKHHLSGKHGGSVLKWNTRLQIAVDAALGLEYLHIGCRPSMVHRDVKSTNILLDD 721 Query 745 LGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP-----WLAPECLPGGANSLSTAMDKW 798 A K++D G+ L E +V + +L PE G L+ D + Sbjct 722 QFTA-------KMADFGLSRSFQLGDESQVSTVVAGTPGYLDPEYYRTG--RLAEMSDVY 772 Query 799 GFGATLLEI 807 FG LLEI Sbjct 773 SFGIVLLEI 781 >sp|O43293|DAPK3_HUMAN Death-associated protein kinase 3 OS=Homo sapiens OX=9606 GN=DAPK3 PE=1 SV=1 Length=454 Score = 80.5 bits (197), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 62/205 (30%), Positives = 102/205 (50%), Gaps = 20/205 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-----WKQEIDILRTLYH 956 +LG G F V C GTG+ A K +K R G ++E++ILR + H Sbjct 18 ELGSGQFAIVR-KC---RQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRH 73 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLH 1015 +II E++ + + L++E V G L D+L + S+ + F +QI +G+ YLH Sbjct 74 PNIITLHDIFENKTD--VVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131 Query 1016 AQHYIHRDLAARNVLLDNDRL----VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 ++ H DL N++L + + +K+ DFG+A + G+E+ + +P F APE Sbjct 132 SKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNI---FGTPEF-VAPE 187 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 + +D+WS GV Y LL+ Sbjct 188 IVNYEPLGLEADMWSIGVITYILLS 212 >sp|Q19469|SAD1_CAEEL Serine/threonine kinase SAD-1 OS=Caenorhabditis elegans OX=6239 GN=sad-1 PE=1 SV=2 Length=914 Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 63/200 (32%), Positives = 97/200 (49%), Gaps = 17/200 (9%) Query 901 RDLGEGHFG--KVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHE 957 + LG+G G K +C TG VA+K + K ++EI I++ + H Sbjct 51 KTLGKGQTGLVKTGTHCI------TGRKVAIKIVNKEKLSESVLQKVEREIAIMKLIEHP 104 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA-QLLLFAQQICEGMAYLHA 1016 H++ E++ K L L++E+V G L DYL R ++ + F +QI + + HA Sbjct 105 HVLHLYDVYENK--KYLYLLLEHVSGGELFDYLVRKGRLMSKEARKFFRQIISALDFCHA 162 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + HRDL N+LLD +K+ DFG+A EG + E + PE ++ Sbjct 163 HNICHRDLKPENLLLDERNNIKVADFGMASLQVEGS----MLETSCGSPHYACPEVIRGE 218 Query 1077 KFY-YASDVWSFGVTLYELL 1095 K+ +DVWS GV LY LL Sbjct 219 KYDGRKADVWSCGVILYALL 238 >sp|Q68UT7|HUNK_PANTR Hormonally up-regulated neu tumor-associated kinase OS=Pan troglodytes OX=9598 GN=HUNK PE=3 SV=1 Length=714 Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 68/213 (32%), Positives = 98/213 (46%), Gaps = 18/213 (8%) Query 893 HKR---YLKKIRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKAL---KADCGPQHRSGW 944 HKR YL R LGEG F KV L+ TGE VA+K + +A Sbjct 55 HKRVGNYLIGSRKLGEGSFAKVREGLHVL------TGEKVAIKVIDKKRAKKDTYVTKNL 108 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLF 1003 ++E I + + H +I + E E S LVME P G+L + + + ++ + Sbjct 109 RREGQIQQMIRHPNITQLLDILET--ENSYYLVMELCPGGNLMHKIYEKKRLEESEARRY 166 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 +Q+ + +LH +HRDL N+LLD D +K+ DFGL+ S Sbjct 167 IRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGS 226 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 P + APE L K+ DVWS GV +Y +LT Sbjct 227 PAYA-APELLARKKYGPKIDVWSIGVNMYAMLT 258 >sp|Q9Y572|RIPK3_HUMAN Receptor-interacting serine/threonine-protein kinase 3 OS=Homo sapiens OX=9606 GN=RIPK3 PE=1 SV=2 Length=518 Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 83/297 (28%), Positives = 135/297 (45%), Gaps = 36/297 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FG V + + G VAVK + + +E+ + +L +E +++ Sbjct 27 VGKGGFGTV----FRAQHRKWGYDVAVKIVNSKA-------ISREVKAMASLDNEFVLRL 75 Query 963 KGCCE----DQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYL 1014 +G E DQ K LV +++ GSL L PR L +LL +++ GM YL Sbjct 76 EGVIEKVNWDQDPKPA-LVTKFMENGSLSGLLQSQCPRPWPLLCRLL---KEVVLGMFYL 131 Query 1015 HAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 H Q+ +HRDL NVLLD + VK+ DFGL+ E G + + + APE Sbjct 132 HDQNPVLLHRDLKPSNVLLDPELHVKLADFGLSTFQGGSQSGTGSGEPGGT-LGYLAPEL 190 Query 1073 LKEY--KFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLTELLE 1129 K ASDV+SFG+ ++ +L + + P+ E + Q + + L EL + Sbjct 191 FVNVNRKASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAVCNRQNRPS---LAELPQ 247 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 G P + + LM+ CW +E RP+F+ +P V + + + S Sbjct 248 AGPETPGLEG----LKELMQLCWSSEPKDRPSFQECLPKTDEVFQMVENNMNAAVST 300 Score = 43.5 bits (101), Expect = 0.011, Method: Compositional matrix adjust. Identities = 61/251 (24%), Positives = 106/251 (42%), Gaps = 51/251 (20%) Query 649 HDIALAFYETASL------MSQVSHTHLAFVHGVCVR-----GPENIMVTEYVEHGPLDV 697 +D+A+ + ++ M+ + + + + GV + P+ +VT+++E+G L Sbjct 45 YDVAVKIVNSKAISREVKAMASLDNEFVLRLEGVIEKVNWDQDPKPALVTKFMENGSLSG 104 Query 698 WLRRERGHVPMAWKMV--VAQQLASALSYLENKN--LVHGNVCGRNILLA---RLGLAE- 749 L+ + P W ++ + +++ + YL ++N L+H ++ N+LL + LA+ Sbjct 105 LLQSQ---CPRPWPLLCRLLKEVVLGMFYLHDQNPVLLHRDLKPSNVLLDPELHVKLADF 161 Query 750 GTSPFIKLS-------DPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 G S F S +PG LG +LAPE STA D + FG Sbjct 162 GLSTFQGGSQSGTGSGEPGGTLG------------YLAPELFVNVNRKASTASDVYSFGI 209 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHR-----LPE-----PSCPQLATLTSQCLTYE 852 + + E L + E RQ+R LP+ P L L C + E Sbjct 210 LMWAVLAGREVELPTEPSLVYEAVCNRQNRPSLAELPQAGPETPGLEGLKELMQLCWSSE 269 Query 853 PTQRPSFRTIL 863 P RPSF+ L Sbjct 270 PKDRPSFQECL 280 >sp|P18265|GSK3A_RAT Glycogen synthase kinase-3 alpha OS=Rattus norvegicus OX=10116 GN=Gsk3a PE=1 SV=1 Length=483 Score = 80.5 bits (197), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 70/211 (33%), Positives = 103/211 (49%), Gaps = 33/211 (16%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I+ +G G FG V Y T E+VA+K + D ++R E+ I+R L H +I Sbjct 122 IKVIGNGSFGVV----YQARLAETRELVAIKKVLQDKRFKNR-----ELQIMRKLDHCNI 172 Query 960 IKYKGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRH------SIGLAQLLLFAQQICE 1009 ++ + GEK L LV+EYVP R + RH I + + ++ Q+ Sbjct 173 VRLRYFFYSSGEKKDELYLNLVLEYVPETVYR--VARHFTKAKLIIPIIYVKVYMYQLFR 230 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGH---EYYRVREDGDSPV 1065 +AY+H+Q HRD+ +N+L+D D V K+ DFG AK + G Y R Sbjct 231 SLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR------- 283 Query 1066 FWYAPECLKEYKFYYAS-DVWSFGVTLYELL 1095 ++ APE + Y +S DVWS G L ELL Sbjct 284 YYRAPELIFGATDYTSSIDVWSAGCVLAELL 314 Score = 36.2 bits (82), Expect = 1.9, Method: Compositional matrix adjust. Identities = 31/128 (24%), Positives = 59/128 (46%), Gaps = 12/128 (9%) Query 685 MVTEYVEHGPLDVW--LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +V EYV V + + +P+ + V QL +L+Y+ ++ + H ++ +N+L+ Sbjct 193 LVLEYVPETVYRVARHFTKAKLIIPIIYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLV 252 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWG 799 + + +KL D G + E V I + APE + GA ++++D W Sbjct 253 ------DPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELI-FGATDYTSSIDVWS 305 Query 800 FGATLLEI 807 G L E+ Sbjct 306 AGCVLAEL 313 >sp|Q5RDH5|AAPK1_PONAB 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Fragment) OS=Pongo abelii OX=9601 GN=PRKAA1 PE=2 SV=2 Length=554 Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 72/201 (36%), Positives = 98/201 (49%), Gaps = 22/201 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957 LG G FGKV + ++ TG VAVK L + RS ++EI L+ H Sbjct 28 LGVGTFGKVKV----GKHELTGHKVAVKILNRQ---KIRSLDVVGKIRREIQNLKLFRHP 80 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA 1016 HIIK + + +VMEYV G L DY+ ++ + + QQI G+ Y H Sbjct 81 HIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR 138 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL NVLLD KI DFGL+ + +G E+ +R SP + APE + Sbjct 139 HMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDG-EF--LRTSCGSPNYA-APEVISG- 193 Query 1077 KFYYA--SDVWSFGVTLYELL 1095 + Y D+WS GV LY LL Sbjct 194 RLYAGPEVDIWSSGVILYALL 214 >sp|Q41639|CDC2_VIGAC Cell division control protein 2 homolog OS=Vigna aconitifolia OX=3918 GN=CDC2 PE=2 SV=1 Length=294 Score = 78.2 bits (191), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 64/207 (31%), Positives = 101/207 (49%), Gaps = 20/207 (10%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYH 956 +K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ + H Sbjct 5 EKVEKIGEGTYGVV----YKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR--DYLPRHSIGLAQLLLFAQQICEGMAYL 1014 +I++ + EK L LV EY+ L + D P Q+ +F QI G+AY Sbjct 61 RNIVRLQDVV--HSEKRLYLVFEYLDLDLKKHMDSSPEFVKDPRQVKMFLYQILCGIAYC 118 Query 1015 HAQHYIHRDLAARNVLLD-NDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070 H+ +HRDL +N+L+D +K+ DFGLA+A +P + V WY AP Sbjct 119 HSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEV------VTLWYRAP 172 Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLT 1096 E L + Y DVWS G E++ Sbjct 173 EILLGSRHYSTPVDVWSVGCIFAEMVN 199 >sp|P53349|M3K1_MOUSE Mitogen-activated protein kinase kinase kinase 1 OS=Mus musculus OX=10090 GN=Map3k1 PE=1 SV=3 Length=1493 Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 64/243 (26%), Positives = 119/243 (49%), Gaps = 23/243 (9%) Query 868 RLQPHNLADVLTVNPDSPASDP--TVFHKRYLK-----KIRDLGEGHFGKVSLYCYDPTN 920 +LQ N D++ + D+P + P T + Y + K + +G G F CY + Sbjct 1188 QLQVENGEDIIIIQQDTPETLPGHTKAKQPYREDAEWLKGQQIGLGAFSS----CYQAQD 1243 Query 921 DGTGEMVAVKAL---KADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGC-CEDQGEKSL 974 GTG ++AVK + + Q ++EI ++ L H +II+ G CE + + Sbjct 1244 VGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMGHLNHPNIIRMLGATCE---KSNY 1300 Query 975 QLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033 L +E++ GS+ L ++ +++ + +Q+ G++YLH IHRD+ N+L+D+ Sbjct 1301 NLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDS 1360 Query 1034 D-RLVKIGDFG-LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091 + ++I DFG A+ +G + + + APE L+ ++ + DVWS G + Sbjct 1361 TGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAI 1420 Query 1092 YEL 1094 E+ Sbjct 1421 IEM 1423 Score = 47.8 bits (112), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 49/226 (22%), Positives = 90/226 (40%), Gaps = 14/226 (6%) Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 ++ A E +M ++H ++ + G + E++ G + L + G Sbjct 1265 QEEVVEALREEIRMMGHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSV-AHLLSKYGAFK 1323 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF---IKLSDPGVGL 764 + + +QL LSYL ++H +V G N+L+ G + F +L+ G G Sbjct 1324 ESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGA 1383 Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE-- 822 G + + + I ++APE L G + D W G ++E+ + P + S Sbjct 1384 GEF-QGQLLGTIAFMAPEVLRG--QQYGRSCDVWSVGCAIIEMAC-AKPPWNAEKHSNHL 1439 Query 823 ----KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 K +P P L + +CL +P RP R +L+ Sbjct 1440 ALIFKIASATTAPSIPSHLSPGLRDVAVRCLELQPQDRPPSRELLK 1485 >sp|Q753D9|PKH3_EREGS Serine/threonine-protein kinase PKH3 OS=Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=PKH3 PE=3 SV=1 Length=726 Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 55/159 (35%), Positives = 76/159 (48%), Gaps = 14/159 (9%) Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLF 1003 K +++L H IIK DQ ++L VM+ P G L L R + A + Sbjct 59 KNTLNLLGQANHPGIIKLYYTFHDQ--ENLYFVMDLAPGGELLQLLRRQRVFSEAWARHY 116 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 Q+ + + Y+H+ IHRDL NVLLD + + I DFG A V + DGD Sbjct 117 MCQLVDTVEYIHSMGVIHRDLKPENVLLDKEGRLMIADFGAAYTVGQSD----AGSDGDK 172 Query 1064 PVF-------WYAPECLKEYKFYYASDVWSFGVTLYELL 1095 P + +PE L E K YY+SDVW+ G LY+ L Sbjct 173 PATSFVGTAEYVSPELLLENKSYYSSDVWALGCMLYQFL 211 Score = 41.6 bits (96), Expect = 0.049, Method: Compositional matrix adjust. Identities = 53/214 (25%), Positives = 90/214 (42%), Gaps = 12/214 (6%) Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715 T +L+ Q +H + ++ EN+ V + G L LRR+R AW Sbjct 60 NTLNLLGQANHPGIIKLY-YTFHDQENLYFVMDLAPGGELLQLLRRQRV-FSEAWARHYM 117 Query 716 QQLASALSYLENKNLVHGNVCGRNILL---ARLGLAE-GTSPFIKLSDPGVGLGALSREE 771 QL + Y+ + ++H ++ N+LL RL +A+ G + + SD G G Sbjct 118 CQLVDTVEYIHSMGVIHRDLKPENVLLDKEGRLMIADFGAAYTVGQSDAGSD-GDKPATS 176 Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQ 830 V +++PE L + S+ D W G L + G P + ++ E E Sbjct 177 FVGTAEYVSPELLLENKSYYSS--DVWALGCMLYQF-LQGTPPFRGQNEMETFEQIVNLD 233 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + P+ P A L S+ L +P+QR + I + Sbjct 234 YTWRIPANPLAAGLVSKILVLDPSQRYTLEQIKK 267 >sp|Q2V419|CKB12_ARATH Cyclin-dependent kinase B1-2 OS=Arabidopsis thaliana OX=3702 GN=CDKB1-2 PE=1 SV=2 Length=311 Score = 78.6 bits (192), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 68/222 (31%), Positives = 104/222 (47%), Gaps = 35/222 (16%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH-----------RSGWKQ 946 +K+ +GEG +GKV Y TG++VA+K + + + Q Sbjct 5 EKLEKVGEGTYGKV----YKAMEKTTGKLVALKKTRLEMDEEGIPPTALREISLLQMLSQ 60 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRDYLPRHSIG--------- 996 I I+R L EH+I+ K KS L LV EY+ L+ ++ H G Sbjct 61 SIYIVRLLCVEHVIQSKDSTVSHSPKSNLYLVFEYLD-TDLKKFIDSHRKGSNPRPLEAS 119 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR-LVKIGDFGLAKAVPEGHEYY 1055 L Q +F Q+ +G+A+ H+ +HRDL +N+LLD D+ ++KI D GL++A + Y Sbjct 120 LVQRFMF--QLFKGVAHCHSHGVLHRDLKPQNLLLDKDKGILKIADLGLSRAFTVPLKAY 177 Query 1056 RVREDGDSPVFWY-APECLKEYKFY-YASDVWSFGVTLYELL 1095 + WY APE L Y A D+WS G E++ Sbjct 178 ----THEIVTLWYRAPEVLLGSTHYSTAVDIWSVGCIFAEMI 215 >sp|Q9XEC8|CRK38_ARATH Cysteine-rich receptor-like protein kinase 38 OS=Arabidopsis thaliana OX=3702 GN=CRK38 PE=3 SV=1 Length=648 Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 69/202 (34%), Positives = 101/202 (50%), Gaps = 18/202 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FG V Y G GE +AVK L G Q ++ E+ +L L H +++K Sbjct 345 IGQGGFGSV----YKGKLPG-GEEIAVKRLTRGSG-QGEIEFRNEVLLLTRLQHRNLVKL 398 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA----YLHAQ- 1017 G C ++G++ + LV E+VP SL ++ L +I EG+A YLH Sbjct 399 LGFC-NEGDEEI-LVYEFVPNSSLDHFIFDEEKRLLLTWDMRARIIEGVARGLVYLHEDS 456 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074 IHRDL A N+LLD K+ DFG+A+ R+ + F Y APE ++ Sbjct 457 QLRIIHRDLKASNILLDAYMNPKVADFGMARLFNMDQTRAVTRKVVGT--FGYMAPEYVR 514 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 F +DV+SFGV L E++T Sbjct 515 NRTFSVKTDVYSFGVVLLEMIT 536 Score = 51.6 bits (122), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 55/215 (26%), Positives = 96/215 (45%), Gaps = 32/215 (15%) Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663 +E ++ G G +GK+ PG G+E+ V K L + F L++ Sbjct 341 FENKIGQGGFGSVYKGKL-------PG---GEEIAV--KRLTRGSGQGEIEFRNEVLLLT 388 Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM--VVAQQLASA 721 ++ H +L + G C G E I+V E+V + LD ++ E + + W M + + +A Sbjct 389 RLQHRNLVKLLGFCNEGDEEILVYEFVPNSSLDHFIFDEEKRLLLTWDMRARIIEGVARG 448 Query 722 LSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERVER-- 775 L YL + ++H ++ NILL +P K++D G+ L + + V R Sbjct 449 LVYLHEDSQLRIIHRDLKASNILLDAY-----MNP--KVADFGMARLFNMDQTRAVTRKV 501 Query 776 ---IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 ++APE + + S D + FG LLE+ Sbjct 502 VGTFGYMAPEYVRN--RTFSVKTDVYSFGVVLLEM 534 >sp|Q9SA72|Y1357_ARATH Probable receptor-like protein kinase At1g30570 OS=Arabidopsis thaliana OX=3702 GN=At1g30570 PE=3 SV=1 Length=849 Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 80/282 (28%), Positives = 128/282 (45%), Gaps = 26/282 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG---WKQEIDILRTLYHEHI 959 +G G FGKV DGT ++A+K P + G ++ EI +L L H H+ Sbjct 526 IGVGGFGKV---YRGELEDGT--LIAIKR----ATPHSQQGLAEFETEIVMLSRLRHRHL 576 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI---GLAQLLLFAQQICEGMAYLHA 1016 + G C++ E + LV EY+ G+LR +L ++ Q L G+ YLH Sbjct 577 VSLIGFCDEHNE--MILVYEYMANGTLRSHLFGSNLPPLSWKQRLEACIGSARGLHYLHT 634 Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + IHRD+ N+LLD + + K+ DFGL+KA P ++ V + PE Sbjct 635 GSERGIIHRDVKTTNILLDENFVAKMSDFGLSKAGPS-MDHTHVSTAVKGSFGYLDPEYF 693 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + + SDV+SFGV L+E + C + PT + I +A+ ++ + L + Sbjct 694 RRQQLTEKSDVYSFGVVLFEAV--CARAVINPTLPKDQINLAEWALSWQKQRNLESIIDS 751 Query 1134 LPRPDKCP--CEVY-HLMKNCWETEASFRPTFENLIPILKTV 1172 R + P E Y + + C E RP ++ L+ V Sbjct 752 NLRGNYSPESLEKYGEIAEKCLADEGKNRPMMGEVLWSLEYV 793 Score = 45.4 bits (106), Expect = 0.004, Method: Compositional matrix adjust. Identities = 66/258 (26%), Positives = 105/258 (41%), Gaps = 46/258 (18%) Query 648 HHDIALAFYETASLM-SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 H LA +ET +M S++ H HL + G C E I+V EY+ +G L R H+ Sbjct 553 HSQQGLAEFETEIVMLSRLRHRHLVSLIGFCDEHNEMILVYEYMANGTL-------RSHL 605 Query 707 ------PMAWKMVVAQQLASA--LSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFI 755 P++WK + + SA L YL + ++H +V NILL +A+ + + Sbjct 606 FGSNLPPLSWKQRLEACIGSARGLHYLHTGSERGIIHRDVKTTNILLDENFVAKMSDFGL 665 Query 756 KLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE-ICFDGEAP 814 + P + +S + +L PE L+ D + FG L E +C A Sbjct 666 SKAGPSMDHTHVSTAVK-GSFGYLDPEYFR--RQQLTEKSDVYSFGVVLFEAVC--ARAV 720 Query 815 LQSRSPSEKEHF------YQRQHRL-------------PEPSCPQLATLTSQCLTYEPTQ 855 + P ++ + +Q+Q L PE S + + +CL E Sbjct 721 INPTLPKDQINLAEWALSWQKQRNLESIIDSNLRGNYSPE-SLEKYGEIAEKCLADEGKN 779 Query 856 RPSFRTILRDLTR-LQPH 872 RP +L L LQ H Sbjct 780 RPMMGEVLWSLEYVLQIH 797 >sp|P18652|KS6AA_CHICK Ribosomal protein S6 kinase 2 alpha OS=Gallus gallus OX=9031 GN=RPS6KA PE=2 SV=1 Length=752 Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 63/219 (29%), Positives = 112/219 (51%), Gaps = 13/219 (6%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGP 938 V S +DP+ F + ++ LG+G FGKV L T + + A+K LK A Sbjct 68 VKEGSEKADPSQF-----ELLKVLGQGSFGKVFL-VRKITPPDSNHLYAMKVLKKATLKV 121 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA 998 + R K E DIL + H ++K + +G+ L L+++++ G L L + + Sbjct 122 RDRVRTKIERDILADVNHPFVVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTE 179 Query 999 Q-LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + + + ++ G+ +LH+ I+RDL N+LLD + +K+ DFGL+K E ++ + Sbjct 180 EDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKK 236 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 V + APE + +++D WS+GV ++E+LT Sbjct 237 AYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLT 275 Score = 66.2 bits (160), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 60/189 (32%), Positives = 87/189 (46%), Gaps = 23/189 (12%) Query 946 QEIDIL-RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLF 1003 +EI+IL R H +II K +D K + LV E + G L D + R + Sbjct 475 EEIEILLRYGQHPNIITLKDVYDDG--KYVYLVTELMRGGELLDKILRQKFFSEREASSV 532 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 IC+ + YLH+Q +HRDL N+L N ++I DFG AK + E Sbjct 533 LHTICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRA--------E 584 Query 1060 DG--DSPVF---WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LI 1112 +G +P + + APE LK + D+WS GV LY +L C + P+ E L Sbjct 585 NGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILT 644 Query 1113 GIAQGQMTV 1121 I G+ +V Sbjct 645 RIGGGKFSV 653 >sp|Q8BZN4|NUAK2_MOUSE NUAK family SNF1-like kinase 2 OS=Mus musculus OX=10090 GN=Nuak2 PE=1 SV=2 Length=639 Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 70/239 (29%), Positives = 108/239 (45%), Gaps = 26/239 (11%) Query 874 LADVLTVNPDSPASDPTV---FHKRYLKK----IRDLGEGHFGKVSLYCYDPTNDGTGEM 926 LAD L +P V HK L+ + LG+G +GKV + +G + Sbjct 27 LADGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVK-----KARESSGRL 81 Query 927 VAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCED------QGEKSLQLVM 978 VA+K+++ D Q ++EI+I+ +L H HII + + +VM Sbjct 82 VAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVGRSRLVTVFENSSKIVIVM 141 Query 979 EYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037 EY G L DY+ R + F +QI + Y H +HRDL N+LLD + + Sbjct 142 EYASRGDLYDYISERPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNI 201 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELL 1095 KI DFGL+ H+ ++ SP++ +PE + + D WS GV LY L+ Sbjct 202 KIADFGLSNLY---HKGKFLQTFCGSPLY-ASPEIVNGKPYVGPEVDSWSLGVLLYILV 256 Score = 35.8 bits (81), Expect = 3.0, Method: Compositional matrix adjust. Identities = 46/167 (28%), Positives = 69/167 (41%), Gaps = 23/167 (14%) Query 661 LMSQVSHTHLAFVHGV----CVRGPEN----IMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 +MS ++H H+ +H V V EN ++V EY G L ++ ER + Sbjct 107 IMSSLNHPHIIAIHEVGRSRLVTVFENSSKIVIVMEYASRGDLYDYIS-ERPRLSERDAR 165 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 +Q+ SAL Y +VH ++ NILL A G IK++D GL L + + Sbjct 166 HFFRQIVSALHYCHQNGIVHRDLKLENILLD----ANGN---IKIAD--FGLSNLYHKGK 216 Query 773 VERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 + P A + G + +D W G LL I G P Sbjct 217 FLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLG-VLLYILVHGTMPF 262 >sp|P57058|HUNK_HUMAN Hormonally up-regulated neu tumor-associated kinase OS=Homo sapiens OX=9606 GN=HUNK PE=1 SV=1 Length=714 Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 68/213 (32%), Positives = 98/213 (46%), Gaps = 18/213 (8%) Query 893 HKR---YLKKIRDLGEGHFGKV--SLYCYDPTNDGTGEMVAVKAL---KADCGPQHRSGW 944 HKR YL R LGEG F KV L+ TGE VA+K + +A Sbjct 55 HKRVGNYLIGSRKLGEGSFAKVREGLHVL------TGEKVAIKVIDKKRAKKDTYVTKNL 108 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLF 1003 ++E I + + H +I + E E S LVME P G+L + + + ++ + Sbjct 109 RREGQIQQMIRHPNITQLLDILET--ENSYYLVMELCPGGNLMHKIYEKKRLEESEARRY 166 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 +Q+ + +LH +HRDL N+LLD D +K+ DFGL+ S Sbjct 167 IRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGS 226 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 P + APE L K+ DVWS GV +Y +LT Sbjct 227 PAYA-APELLARKKYGPKIDVWSIGVNMYAMLT 258 >sp|Q75V57|SAPK9_ORYSJ Serine/threonine-protein kinase SAPK9 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK9 PE=1 SV=1 Length=361 Score = 79.3 bits (194), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 74/222 (33%), Positives = 109/222 (49%), Gaps = 24/222 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 ++++G G+FG L N +G++VAVK + D G + ++EI R+L H +I Sbjct 25 VKEIGSGNFGVARLM----RNRASGDLVAVKYI--DRGEKIDENVQREIINHRSLRHPNI 78 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA 1016 I++K L +VMEY G L + + R S A+ F QQ+ G++Y H+ Sbjct 79 IRFKEVI--LTPTHLAIVMEYASGGELFERICSAGRFSEDEARF--FFQQLISGVSYCHS 134 Query 1017 QHYIHRDLAARNVLLDNDRL--VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL- 1073 HRDL N LLD +KI DFG +K+ + + + +P + APE L Sbjct 135 MQVCHRDLKLENTLLDGSTAPRLKICDFGYSKS---SVLHSQPKSTVGTPA-YIAPEVLL 190 Query 1074 -KEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLELI 1112 KEY A DVWS GVTLY +L + P P F + I Sbjct 191 KKEYDGKIA-DVWSCGVTLYVMLVGAYPFEDPEDPKNFRKTI 231 >sp|Q7Z2Y5|NRK_HUMAN Nik-related protein kinase OS=Homo sapiens OX=9606 GN=NRK PE=1 SV=2 Length=1582 Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 76/301 (25%), Positives = 132/301 (44%), Gaps = 56/301 (19%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-------------QHRSGWK-- 945 + +G G +G++ L ++ TG AVK + A P Q GW+ Sbjct 29 KTIGLGTYGRIYLGLHE----KTGAFTAVKVMNARKTPLPEIGRRVRVNKYQKSVGWRYS 84 Query 946 -------QEIDILRTL-YHEHIIKYKGC---CEDQGEK-SLQLVMEYVPLGSLRDYL--- 990 E+++LR +H++I+ + G G++ L +VME GS+ D + Sbjct 85 DEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPGQRHQLWMVMELCAAGSVTDVVRMT 144 Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 S+ + ++I +G+A+LHA IHRD+ +NVLL ++ VK+ DFG++ V Sbjct 145 SNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKGQNVLLTHNAEVKLVDFGVSAQVSR 204 Query 1051 GHEYYRVREDGDSPVFWYAPECLK-----EYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + R +W APE + + Y SDVWS G+T E+ + +PP Sbjct 205 TNGR---RNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDVWSVGITAIEM-----AEGAPP 256 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L+ + + +LR + + R + ++ M+ C FRPT N+ Sbjct 257 LCNLQPL---EALFVILRESAPTVKSSGWSR------KFHNFMEKCTIKNFLFRPTSANM 307 Query 1166 I 1166 + Sbjct 308 L 308 Score = 37.4 bits (85), Expect = 1.3, Method: Compositional matrix adjust. Identities = 49/200 (25%), Positives = 76/200 (38%), Gaps = 29/200 (15%) Query 632 DRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTH-LAFVHGVCVRGPENIMVTEY 689 D ++LR L +L S H ++FY +S H L V +C G VT Sbjct 85 DEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPGQRHQLWMVMELCAAG----SVT-- 138 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 DV + W + +++ L++L ++H ++ G+N+LL Sbjct 139 ------DVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKGQNVLLTH----- 187 Query 750 GTSPFIKLSDPGVGLGALSREERVERIP----WLAPE---CLPGGANSLSTAMDKWGFGA 802 + +KL D GV R W+APE C S D W G Sbjct 188 --NAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDVWSVGI 245 Query 803 TLLEICFDGEAPLQSRSPSE 822 T +E+ +G PL + P E Sbjct 246 TAIEMA-EGAPPLCNLQPLE 264 >sp|O08644|EPHB6_MOUSE Ephrin type-B receptor 6 OS=Mus musculus OX=10090 GN=Ephb6 PE=2 SV=4 Length=1014 Score = 81.6 bits (200), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 73/290 (25%), Positives = 131/290 (45%), Gaps = 36/290 (12%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DPT Y+K +G G FG+V P + VA++AL A + + Sbjct 659 DPT-----YIKIEEVIGAGSFGEVRRGRLQPRGRRE-QAVAIQALWAGGAESLKMTFLGR 712 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ- 1006 +L H +I++ +G + + ++ E + LG L +L + + L L A Q Sbjct 713 AALLGQFQHPNILRLEGVVTK--SRPVMVLTELMELGPLDSFLRQREGQFSSLQLVAMQR 770 Query 1007 -ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 + M YL + ++HR L+AR+VL+++ + K+ G + P+G S + Sbjct 771 GVAAAMQYLSSFAFVHRALSARSVLVNSHLVCKVARLGHS---PQGS---------SSLL 818 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 W APE + K+ +SDVWSFG+ ++E++++ + M + Sbjct 819 RWAAPEVITHGKYTTSSDVWSFGILMWEVMSYGER--------------PYWDMNEQEVL 864 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 +E+ RLP P CP ++ LM + W+ + + RP F+ L+ + K Sbjct 865 NAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRK 914 Score = 65.5 bits (158), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 50/212 (24%), Positives = 94/212 (44%), Gaps = 32/212 (15%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 R R ++ + + + + F A+L+ Q H ++ + GV + +++TE + Sbjct 685 RGRREQAVAIQALWAGGAESLKMTFLGRAALLGQFQHPNILRLEGVVTKSRPVMVLTELM 744 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL--------L 742 E GPLD +LR+ G + + + +A+A+ YL + VH + R++L + Sbjct 745 ELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRALSARSVLVNSHLVCKV 804 Query 743 ARLGLA-EGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 ARLG + +G+S ++ W APE + G +T+ D W FG Sbjct 805 ARLGHSPQGSSSLLR---------------------WAAPEVITHG--KYTTSSDVWSFG 841 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833 + E+ GE P + E + +++ RL Sbjct 842 ILMWEVMSYGERPYWDMNEQEVLNAIEQEFRL 873 >sp|Q9LN59|WAKLK_ARATH Putative wall-associated receptor kinase-like 11 OS=Arabidopsis thaliana OX=3702 GN=WAKL11 PE=3 SV=2 Length=788 Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 70/260 (27%), Positives = 114/260 (44%), Gaps = 18/260 (7%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 G VAVK K + E+ IL + H H++K GCC + + LV E++P Sbjct 473 GRTVAVKKSKV-VDEDKLEEFINEVVILSQINHRHVVKLLGCCLET--EVPTLVYEFIPN 529 Query 984 GSLRDYLPRHSIGLAQL----LLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRL 1036 G+L ++ S + L A I ++YLH+ HRD+ + N+LLD Sbjct 530 GNLFQHIHEESDDYTKTWGMRLRIAVDIAGALSYLHSAASSPIYHRDIKSTNILLDEKYR 589 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 K+ DFG +++V H ++ G V + PE ++ SDV+SFGV L EL+T Sbjct 590 TKVSDFGTSRSVTIDHTHWTTVISG--TVGYVDPEYYGSSQYTDKSDVYSFGVVLVELIT 647 Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE----VYHLMKNCW 1152 + + E+ G+A ++ E + R D C E V +L + C Sbjct 648 G-EKPVITVSNSQEIRGLADHFRVAMKENRFFEIMDARIR-DGCKPEQVMAVANLARRCL 705 Query 1153 ETEASFRPTFENLIPILKTV 1172 ++ RP + L+ + Sbjct 706 NSKGKKRPCMRKVFTDLEKI 725 Score = 62.8 bits (151), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 76/328 (23%), Positives = 128/328 (39%), Gaps = 74/328 (23%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LGQG + VY+G L + ++ K+ DED L Sbjct 457 LGQGGQGTVYKGMLVDGRTVAVKKSKVVDEDKLEE------------------------- 491 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM-- 712 F ++SQ++H H+ + G C+ +V E++ +G L + E W M Sbjct 492 FINEVVILSQINHRHVVKLLGCCLETEVPTLVYEFIPNGNLFQHIHEESDDYTKTWGMRL 551 Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 +A +A ALSYL + + H ++ NILL K+SD G SR Sbjct 552 RIAVDIAGALSYLHSAASSPIYHRDIKSTNILLDE-------KYRTKVSDFGT-----SR 599 Query 770 EERVERIPW----------LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 ++ W + PE G++ + D + FG L+E+ GE P+ + S Sbjct 600 SVTIDHTHWTTVISGTVGYVDPEYY--GSSQYTDKSDVYSFGVVLVEL-ITGEKPVITVS 656 Query 820 PSEK-----EHF--YQRQHRLPE-------PSCP-----QLATLTSQCLTYEPTQRPSFR 860 S++ +HF +++R E C +A L +CL + +RP R Sbjct 657 NSQEIRGLADHFRVAMKENRFFEIMDARIRDGCKPEQVMAVANLARRCLNSKGKKRPCMR 716 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASD 888 + DL ++ ++ + D A D Sbjct 717 KVFTDLEKILASQEDSLVNIENDDGADD 744 >sp|Q15349|KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 OS=Homo sapiens OX=9606 GN=RPS6KA2 PE=1 SV=2 Length=733 Score = 81.3 bits (199), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 62/212 (29%), Positives = 110/212 (52%), Gaps = 13/212 (6%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWK 945 +DP+ F + ++ LG+G +GKV L +D G++ A+K LK A + R K Sbjct 54 ADPSQF-----ELLKVLGQGSYGKVFLVRKVKGSDA-GQLYAMKVLKKATLKVRDRVRSK 107 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ-LLLFA 1004 E DIL + H I+K + +G+ L L+++++ G L L + + + + + Sbjct 108 MERDILAEVNHPFIVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYL 165 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 ++ + +LH+ I+RDL N+LLD + +KI DFGL+K E ++ + Sbjct 166 AELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSK---EAIDHDKRAYSFCGT 222 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 + + APE + ++D WSFGV ++E+LT Sbjct 223 IEYMAPEVVNRRGHTQSADWWSFGVLMFEMLT 254 Score = 62.8 bits (151), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 64/232 (28%), Positives = 100/232 (43%), Gaps = 44/232 (19%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL-RTLYHEHII 960 D+G G + C + T AVK + + + +EI+IL R H +II Sbjct 420 DIGVGSYS----VCKRCVHKATDTEYAVKIID-----KSKRDPSEEIEILLRYGQHPNII 470 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ--------ICEGMA 1012 K +D K + LVME + G L D + R F+++ I + M Sbjct 471 TLKDVYDDG--KFVYLVMELMRGGELLDRILRQR-------YFSEREASDVLCTITKTMD 521 Query 1013 YLHAQHYIHRDLAARNVLLDND----RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-- 1066 YLH+Q +HRDL N+L ++ +++ DFG AK + G+ +P + Sbjct 522 YLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLM------TPCYTA 575 Query 1067 -WYAPECLKEYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELIG 1113 + APE LK + A D+WS G+ LY +L + P + L IG Sbjct 576 NFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIG 627 >sp|P06244|KAPA_YEAST cAMP-dependent protein kinase type 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TPK1 PE=1 SV=3 Length=397 Score = 79.7 bits (195), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 62/200 (31%), Positives = 99/200 (50%), Gaps = 17/200 (9%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTLYHE 957 +R LG G FG+V L + G A+K LK + + + E +L + H Sbjct 90 LRTLGTGSFGRVHLI----RSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHP 145 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL--LFAQQICEGMAYLH 1015 II+ G +D + + ++M+Y+ G L L R S + +A ++C + YLH Sbjct 146 FIIRMWGTFQDA--QQIFMIMDYIEGGELFSLL-RKSQRFPNPVAKFYAAEVCLALEYLH 202 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 ++ I+RDL N+LLD + +KI DFG AK VP+ Y + D + APE + Sbjct 203 SKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVT--YTLCGTPD----YIAPEVVST 256 Query 1076 YKFYYASDVWSFGVTLYELL 1095 + + D WSFG+ +YE+L Sbjct 257 KPYNKSIDWWSFGILIYEML 276 Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 45/197 (23%), Positives = 84/197 (43%), Gaps = 11/197 (6%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 ++S V+H + + G + M+ +Y+E G L LR+ + P A ++ Sbjct 138 MLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQ-RFPNPVAKFYAAEVCL 196 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-WL 779 AL YL +K++++ ++ NILL + G IK++D G + P ++ Sbjct 197 ALEYLHSKDIIYRDLKPENILLDKNG-------HIKITDFGFAKYVPDVTYTLCGTPDYI 249 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP 839 APE + + ++D W FG + E+ S + E + R P Sbjct 250 APEVV--STKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNE 307 Query 840 QLATLTSQCLTYEPTQR 856 + L S+ +T + +QR Sbjct 308 DVKDLLSRLITRDLSQR 324 >sp|Q99JP0|M4K3_MOUSE Mitogen-activated protein kinase kinase kinase kinase 3 OS=Mus musculus OX=10090 GN=Map4k3 PE=1 SV=4 Length=894 Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 56/199 (28%), Positives = 102/199 (51%), Gaps = 14/199 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I+ +G G +G V Y N TGE+ A+K +K + G + + +QEI +++ H +I Sbjct 19 IQRIGSGTYGDV----YKARNVNTGELAAIKVIKLEPG-EDFAVVQQEIIMMKDCKHPNI 73 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 + Y G + + L + ME+ GSL+D Y + Q+ +++ +G+ YLH++ Sbjct 74 VAYFGSYLRRDK--LWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKG 131 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL---KE 1075 +HRD+ N+LL ++ VK+ DFG++ + R+ +W APE ++ Sbjct 132 KMHRDIKGANILLTDNGHVKLADFGVSAQITAT---IAKRKSFIGTPYWMAPEVAAVERK 188 Query 1076 YKFYYASDVWSFGVTLYEL 1094 + D+W+ G+T EL Sbjct 189 GGYNQLCDLWAVGITAIEL 207 Score = 40.8 bits (94), Expect = 0.10, Method: Compositional matrix adjust. Identities = 67/304 (22%), Positives = 115/304 (38%), Gaps = 52/304 (17%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 R Q++ + +G GT +VY+ R + G+ + + Sbjct 10 RNPQEDFELIQRIGSGTYGDVYKAR----------------------NVNTGELAAIKVI 47 Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRR 701 L+P D A+ E +M H ++ G +R + + E+ G L D++ Sbjct 48 KLEPGE-DFAVVQQEII-MMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIY--H 103 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 G + V+++ L YL +K +H ++ G NILL G +KL+D G Sbjct 104 VTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNG-------HVKLADFG 156 Query 762 VG---LGALSREERVERIP-WLAPECLP----GGANSLSTAMDKWGFGATLLEIC----- 808 V +++ + P W+APE GG N L D W G T +E+ Sbjct 157 VSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLC---DLWAVGITAIELAELQPP 213 Query 809 -FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 FD P+++ K +F + + LT P +RP+ +L+ Sbjct 214 MFDLH-PMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKKRPNAEKLLQHPF 272 Query 868 RLQP 871 QP Sbjct 273 VTQP 276 >sp|O04534|LRK51_ARATH Putative L-type lectin-domain containing receptor kinase V.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK51 PE=3 SV=1 Length=666 Score = 80.9 bits (198), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 65/207 (31%), Positives = 99/207 (48%), Gaps = 21/207 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---EIDILRT 953 K LG+G FGKV Y T + +AVK + D R G ++ EI + Sbjct 344 FKDTEVLGKGGFGKV----YKGTLPVSNVEIAVKMVSHDS----RQGMREFIAEIATIGR 395 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEG 1010 L H ++++ +G C +GE L LV + + GSL +L G +Q + + G Sbjct 396 LRHPNLVRLQGYCRHKGE--LYLVYDCMAKGSLDKFLYHQQTGNLDWSQRFKIIKDVASG 453 Query 1011 MAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH Q IHRD+ N+LLD + K+GDFGLAK G + G + + Sbjct 454 LYYLHQQWVQVIIHRDIKPANILLDANMNAKLGDFGLAKLCDHGTDPQTSHVAG--TLGY 511 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYEL 1094 +PE + K SDV++FG+ + E+ Sbjct 512 ISPELSRTGKASTRSDVFAFGIVMLEI 538 >sp|Q9SYS7|CRK39_ARATH Putative cysteine-rich receptor-like protein kinase 39 OS=Arabidopsis thaliana OX=3702 GN=CRK39 PE=3 SV=1 Length=659 Score = 80.9 bits (198), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 66/201 (33%), Positives = 97/201 (48%), Gaps = 16/201 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V Y N G+ VAVK L G Q +K E+ +L L H +++K Sbjct 359 LGQGGFGTV--YKGTLLN---GQEVAVKRLTKGSG-QGDIEFKNEVSLLTRLQHRNLVKL 412 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017 G C ++G++ + LV E+VP SL ++ R + + I G+ YLH Sbjct 413 LGFC-NEGDEQI-LVYEFVPNSSLDHFIFDDEKRSLLTWEMRYRIIEGIARGLLYLHEDS 470 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 IHRDL A N+LLD + K+ DFG A+ + + + APE L Sbjct 471 QLKIIHRDLKASNILLDAEMNPKVADFGTARLFDSDETRAETKRIAGTRGY-MAPEYLNH 529 Query 1076 YKFYYASDVWSFGVTLYELLT 1096 + SDV+SFGV L E+++ Sbjct 530 GQISAKSDVYSFGVMLLEMIS 550 Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 78/299 (26%), Positives = 124/299 (41%), Gaps = 57/299 (19%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 E + + LGQG VY+G L GQE V +K L Sbjct 352 EFSSENTLGQGGFGTVYKGTLL-----------------------NGQE--VAVKRLTKG 386 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 + F SL++++ H +L + G C G E I+V E+V + LD ++ + Sbjct 387 SGQGDIEFKNEVSLLTRLQHRNLVKLLGFCNEGDEQILVYEFVPNSSLDHFIFDDEKRSL 446 Query 708 MAWKM--VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + W+M + + +A L YL + ++H ++ NILL AE +P K++D G Sbjct 447 LTWEMRYRIIEGIARGLLYLHEDSQLKIIHRDLKASNILLD----AE-MNP--KVADFGT 499 Query 763 GLGALSREERVE--RIP----WLAPECLPGGANSLSTAMDKWGFGATLLEIC-------F 809 S E R E RI ++APE L G +S D + FG LLE+ F Sbjct 500 ARLFDSDETRAETKRIAGTRGYMAPEYLNHG--QISAKSDVYSFGVMLLEMISGERNNSF 557 Query 810 DGE---APLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTIL 863 +GE A R K + +P +L + C+ PT+RP+ +++ Sbjct 558 EGEGLAAFAWKRWVEGKPEIIIDPFLIEKPRNEIIKLIQIGLLCVQENPTKRPTMSSVI 616 >sp|Q6BNF3|STE20_DEBHA Serine/threonine-protein kinase STE20 OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=STE20 PE=3 SV=2 Length=1079 Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 56/208 (27%), Positives = 104/208 (50%), Gaps = 13/208 (6%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP +K +K +G+G G V Y N + + VA+K + + P+ + E Sbjct 796 DPNELYKDLMK----IGQGASGGV--YIAHDVNHRS-QTVAIKQMNLEQQPK-KELIINE 847 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +++ HE+I+ + +G+ L +VMEY+ GSL + + + Q+ ++ Sbjct 848 ILVMKGSKHENIVNFIDSYLLRGD--LWVVMEYMEGGSLTEIVTHSVMTEGQIGAVCRET 905 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 +G+ +LH++ IHRD+ + N+LL+ D +K+ DFG + +E R +W Sbjct 906 LKGLRFLHSKGVIHRDIKSDNILLNIDGNIKMTDFGFCAQI---NEINLKRTTMVGTPYW 962 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095 APE + ++ DVWS G+ + E++ Sbjct 963 MAPEVVSRKEYGPKVDVWSLGIMIIEMI 990 Score = 37.7 bits (86), Expect = 0.88, Method: Compositional matrix adjust. Identities = 42/167 (25%), Positives = 72/167 (43%), Gaps = 22/167 (13%) Query 661 LMSQVSHTHLA-FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQ 717 +M H ++ F+ +RG + +V EY+E G L + H M + V ++ Sbjct 850 VMKGSKHENIVNFIDSYLLRG-DLWVVMEYMEGGSLTEIVT----HSVMTEGQIGAVCRE 904 Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERV 773 L +L +K ++H ++ NILL G IK++D G + L R V Sbjct 905 TLKGLRFLHSKGVIHRDIKSDNILLNIDG-------NIKMTDFGFCAQINEINLKRTTMV 957 Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 W+APE + +D W G ++E+ +GE P + +P Sbjct 958 GTPYWMAPEVV--SRKEYGPKVDVWSLGIMIIEM-IEGEPPYLNETP 1001 >sp|Q75H77|SAPKA_ORYSJ Serine/threonine-protein kinase SAPK10 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK10 PE=1 SV=1 Length=362 Score = 79.3 bits (194), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 79/239 (33%), Positives = 115/239 (48%), Gaps = 27/239 (11%) Query 885 PASDPTVFHK--RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 P D + H RY + +RD+G G+FG L + G++VAVK ++ G + Sbjct 10 PGMDMPIMHDGDRY-ELVRDIGSGNFGVARLM----RSRADGQLVAVKYIER--GDKIDE 62 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQ 999 ++EI R+L H +II++K L +VMEY G L + + R S A+ Sbjct 63 NVQREIINHRSLRHPNIIRFKEVI--LTPTHLAIVMEYASGGELFERICNAGRFSEDEAR 120 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL--VKIGDFGLAKAVPEGHEYYRV 1057 F QQ+ G++Y H+ HRDL N LLD +KI DFG +K+ + + Sbjct 121 F--FFQQLISGVSYCHSMQVCHRDLKLENTLLDGSTAPRLKICDFGYSKS---SVLHSQP 175 Query 1058 REDGDSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLELI 1112 + +P + APE L KEY A DVWS GVTLY +L + P P F + I Sbjct 176 KSTVGTPA-YIAPEVLLKKEYDGKIA-DVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTI 232 Score = 34.3 bits (77), Expect = 7.0, Method: Compositional matrix adjust. Identities = 46/191 (24%), Positives = 75/191 (39%), Gaps = 37/191 (19%) Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER 775 QQL S +SY + VC R++ L L T+P +K+ D G ++ + Sbjct 124 QQLISGVSYCHSM-----QVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKST 178 Query 776 I---PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832 + ++APE L A D W G TL + G P + P E ++F + R Sbjct 179 VGTPAYIAPEVLLKKEYDGKIA-DVWSCGVTLY-VMLVGAYPFE--DPDEPKNFRKTIQR 234 Query 833 L--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 + + S P ++ +C RDL +A + NP + S P Sbjct 235 ILGVQYSIPDYVHISPEC---------------RDL-------IARIFVANPATRISIPE 272 Query 891 V-FHKRYLKKI 900 + H +LK + Sbjct 273 IRNHPWFLKNL 283 >sp|Q9SA25|WAKLG_ARATH Wall-associated receptor kinase-like 8 OS=Arabidopsis thaliana OX=3702 GN=WAKL8 PE=2 SV=1 Length=720 Score = 80.9 bits (198), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 73/263 (28%), Positives = 123/263 (47%), Gaps = 13/263 (5%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 G +VAVK KA ++ + EI +L + H +++K GCC + + LV E++P Sbjct 412 GMIVAVKKSKA-LKEENLEEFINEIILLSQINHRNVVKILGCCLET--EVPILVYEFIPN 468 Query 984 GSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQHYI---HRDLAARNVLLDNDRL 1036 +L D+L S + L A ++ + ++YLH+ I HRD+ + N+LLD Sbjct 469 RNLFDHLHNPSEDFPMSWEVRLCIACEVADALSYLHSAVSIPIYHRDVKSTNILLDEKHR 528 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 K+ DFG++++V + G + + PE L+ F SDV+SFGV L ELLT Sbjct 529 AKVSDFGISRSVAIDDTHLTTIVQG--TIGYVDPEYLQSNHFTGKSDVYSFGVLLIELLT 586 Query 1097 HCDSSQSPPTKFLELIGIAQGQ-MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155 + + ++G + M RL E+L+ + + V L + C Sbjct 587 GEKPVSLLRRQEVRMLGAYFLEAMRNDRLHEILDARIKEECDREEVLAVAKLARRCLSLN 646 Query 1156 ASFRPTFENLIPILKTVHEKYQG 1178 + RPT ++ L + K +G Sbjct 647 SEHRPTMRDVFIELDRMQSKRKG 669 Score = 62.0 bits (149), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 74/304 (24%), Positives = 124/304 (41%), Gaps = 63/304 (21%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LGQG + VY+G L ED ++ + + L+ + Sbjct 396 LGQGGQGTVYKGML---------------EDGMIVAVKKSKALK----------EENLEE 430 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F L+SQ++H ++ + G C+ I+V E++ + L L PM+W ++ Sbjct 431 FINEIILLSQINHRNVVKILGCCLETEVPILVYEFIPNRNLFDHLHNPSEDFPMSWEVRL 490 Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 +A ++A ALSYL + + H +V NILL A K+SD G+ Sbjct 491 CIACEVADALSYLHSAVSIPIYHRDVKSTNILLDEKHRA-------KVSDFGISRSVAID 543 Query 770 EERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + + I ++ PE L +N + D + FG L+E+ GE P+ E Sbjct 544 DTHLTTIVQGTIGYVDPEYLQ--SNHFTGKSDVYSFGVLLIEL-LTGEKPVSLLRRQEVR 600 Query 825 ----HFYQ--RQHRLPE-------PSCPQ-----LATLTSQCLTYEPTQRPSFRTILRDL 866 +F + R RL E C + +A L +CL+ RP+ R + +L Sbjct 601 MLGAYFLEAMRNDRLHEILDARIKEECDREEVLAVAKLARRCLSLNSEHRPTMRDVFIEL 660 Query 867 TRLQ 870 R+Q Sbjct 661 DRMQ 664 >sp|Q9Y884|SKH1_SCHPO MAP kinase kinase skh1/pek1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=skh1 PE=3 SV=1 Length=363 Score = 79.0 bits (193), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 59/200 (30%), Positives = 90/200 (45%), Gaps = 14/200 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG G V GT + A+K + A + +E+ I R+ +I Sbjct 82 MNSLGEGVSGSVR----KCRIRGTQMIFAMKTVLAAPNTALQKQLLRELKINRSCTSPYI 137 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQICEGMAYL 1014 +KY G C + E L + MEY GSL R G L A + G++YL Sbjct 138 VKYYGACYNNAECQLNIAMEYCGAGSLDAIYKRVRSQGGRTGERPLGKIAFGVLSGLSYL 197 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H + IHRD+ N+LL + VK+ DFG++ G + ++ APE + Sbjct 198 HDRKIIHRDIKPSNILLTSKGQVKLCDFGVS-----GELVNSLAGTFTGTSYYMAPERIS 252 Query 1075 EYKFYYASDVWSFGVTLYEL 1094 + +SD+WS G+TL E+ Sbjct 253 GGSYTISSDIWSLGLTLMEV 272 Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 51/193 (26%), Positives = 83/193 (43%), Gaps = 27/193 (14%) Query 631 RDRGQELRVVLK-VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE---NIMV 686 R RG ++ +K VL + + + + ++ +G C E NI + Sbjct 97 RIRGTQMIFAMKTVLAAPNTALQKQLLRELKINRSCTSPYIVKYYGACYNNAECQLNIAM 156 Query 687 TEYVEHGPLDVWLRRER------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNI 740 EY G LD +R R G P+ +A + S LSYL ++ ++H ++ NI Sbjct 157 -EYCGAGSLDAIYKRVRSQGGRTGERPLG---KIAFGVLSGLSYLHDRKIIHRDIKPSNI 212 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDK 797 LL G +KL D GV G L ++APE + GG+ ++S+ D Sbjct 213 LLTSKGQ-------VKLCDFGVS-GELVNSLAGTFTGTSYYMAPERISGGSYTISS--DI 262 Query 798 WGFGATLLEICFD 810 W G TL+E+ + Sbjct 263 WSLGLTLMEVALN 275 >sp|C0LGG7|Y1534_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g53420 OS=Arabidopsis thaliana OX=3702 GN=At1g53420 PE=2 SV=2 Length=953 Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 85/288 (30%), Positives = 133/288 (46%), Gaps = 41/288 (14%) Query 903 LGEGHFGKV---SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +GEG FG V L+ DGT ++AVK L +R + EI ++ L+H ++ Sbjct 630 IGEGGFGPVYKGKLF------DGT--IIAVKQLSTGSKQGNRE-FLNEIGMISALHHPNL 680 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLL---FAQQIC----EG 1010 +K GCC + G+ L LV E+V SL L P+ + QL L ++IC G Sbjct 681 VKLYGCCVEGGQ--LLLVYEFVENNSLARALFGPQET----QLRLDWPTRRKICIGVARG 734 Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 +AYLH + +HRD+ A NVLLD KI DFGLAK E + R G F Sbjct 735 LAYLHEESRLKIVHRDIKATNVLLDKQLNPKISDFGLAKLDEEDSTHISTRIAG---TFG 791 Query 1068 Y-APECLKEYKFYYASDVWSFGVTLYELL----THCDSSQSPPTKFLELIGIAQGQMTVL 1122 Y APE +DV+SFG+ E++ + S++ ++ + + + + +L Sbjct 792 YMAPEYAMRGHLTDKADVYSFGIVALEIVHGRSNKIERSKNNTFYLIDWVEVLREKNNLL 851 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 L + G R + +M C +E RP+ ++ +L+ Sbjct 852 ELVD-PRLGSEYNREEAMTMIQIAIM--CTSSEPCERPSMSEVVKMLE 896 Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 62/250 (25%), Positives = 107/250 (43%), Gaps = 57/250 (23%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH--------GPLDVWLRRERGHV 706 F ++S + H +L ++G CV G + ++V E+VE+ GP + LR + Sbjct 665 FLNEIGMISALHHPNLVKLYGCCVEGGQLLLVYEFVENNSLARALFGPQETQLRLDW--- 721 Query 707 PMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 P K+ + +A L+YL ++ +VH ++ N+LL + +P K+SD G Sbjct 722 PTRRKICIG--VARGLAYLHEESRLKIVHRDIKATNVLLDK-----QLNP--KISD--FG 770 Query 764 LGALSREERV---ERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 L L E+ RI ++APE G L+ D + FG LEI ++ Sbjct 771 LAKLDEEDSTHISTRIAGTFGYMAPEYAMRG--HLTDKADVYSFGIVALEIVHGRSNKIE 828 Query 817 SRSPSEKEHFY--------QRQHRLPEPSCPQLAT------------LTSQCLTYEPTQR 856 S+ FY + ++ L E P+L + + C + EP +R Sbjct 829 R---SKNNTFYLIDWVEVLREKNNLLELVDPRLGSEYNREEAMTMIQIAIMCTSSEPCER 885 Query 857 PSFRTILRDL 866 PS +++ L Sbjct 886 PSMSEVVKML 895 >sp|A0A1D6E0S8|WAK17_MAIZE Wall-associated receptor kinase 17 OS=Zea mays OX=4577 GN=WAK17 PE=1 SV=1 Length=856 Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 11/160 (7%) Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQ 999 + EI IL + H +++K GCC + + LV E++ G+L ++ + + Sbjct 568 FVNEIAILSQIDHPNVVKLLGCCLET--QVPLLVYEFISNGTLFQHIHNRNATRPLTWED 625 Query 1000 LLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 L A + + +AYLH+ IHRD+ + N+LLD + + KI DFG +++VP + Sbjct 626 CLRIAAETADALAYLHSASSIPIIHRDIKSSNILLDGNFVAKIADFGASRSVPFDQTHIT 685 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 G + + PE + + SDV+SFGV L ELLT Sbjct 686 TLIQGT--IGYLDPEYFQSSQLTEKSDVYSFGVVLAELLT 723 Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 62/302 (21%), Positives = 122/302 (40%), Gaps = 41/302 (14%) Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 KV D S + F +++SQ+ H ++ + G C+ ++V E++ +G L + Sbjct 558 KVFDESQVE---QFVNEIAILSQIDHPNVVKLLGCCLETQVPLLVYEFISNGTLFQHIHN 614 Query 702 ERGHVPMAWK--MVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIK 756 P+ W+ + +A + A AL+YL + + ++H ++ NILL +A K Sbjct 615 RNATRPLTWEDCLRIAAETADALAYLHSASSIPIIHRDIKSSNILLDGNFVA-------K 667 Query 757 LSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G + + I +L PE ++ L+ D + FG L E+ Sbjct 668 IADFGASRSVPFDQTHITTLIQGTIGYLDPEYFQ--SSQLTEKSDVYSFGVVLAEL-LTR 724 Query 812 EAPLQSRSPSEKEHFYQ------RQHRL------------PEPSCPQLATLTSQCLTYEP 853 + P+ + P + + + RL E C +A L+ +CL + Sbjct 725 QKPISAARPEDSCNLAMHLVVLFNKGRLLQEIEPHILAEAGEDQCYAVAELSVRCLNVKG 784 Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 +RP+ + L L+ D D + + +++L + R + +VS Sbjct 785 EERPAMVVVASVLQELRRSFTIDQAVGIKDESIQENSEQEEKHLHESRSIPSLQSSEVST 844 Query 914 YC 915 C Sbjct 845 QC 846 >sp|O65472|CRK12_ARATH Putative cysteine-rich receptor-like protein kinase 12 OS=Arabidopsis thaliana OX=3702 GN=CRK12 PE=3 SV=3 Length=659 Score = 80.9 bits (198), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 72/206 (35%), Positives = 97/206 (47%), Gaps = 20/206 (10%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 K LG+G FG+V Y T G VAVK L + Q +K E+ ++ L H + Sbjct 338 KTNKLGQGGFGEV----YKGTLVN-GTEVAVKRL-SKTSEQGAQEFKNEVVLVAKLQHRN 391 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAY 1013 ++K G C + EK L V E+VP SL DY QL I G+ Y Sbjct 392 LVKLLGYCLEPEEKIL--VYEFVPNKSL-DYFLFDPTKQGQLDWTKRYNIIGGITRGILY 448 Query 1014 LHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA- 1069 LH IHRDL A N+LLD D + KI DFG+A+ G + + F Y Sbjct 449 LHQDSRLTIIHRDLKASNILLDADMIPKIADFGMARI--SGIDQSVANTKRIAGTFGYMP 506 Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095 PE + +F SDV+SFGV + E++ Sbjct 507 PEYVIHGQFSMKSDVYSFGVLILEII 532 Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 68/321 (21%), Positives = 124/321 (39%), Gaps = 53/321 (17%) Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 TL+ QL F ++ + + + LGQG VY+G L V G+ Sbjct 318 TLHFQQLDFKTIEVATENFAKTNKLGQGGFGEVYKGTL-VNGT----------------- 359 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 V +K L + A F L++++ H +L + G C+ E I+V E+V Sbjct 360 -------EVAVKRLSKTSEQGAQEFKNEVVLVAKLQHRNLVKLLGYCLEPEEKILVYEFV 412 Query 691 EHGPLDVWLR--RERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745 + LD +L ++G + + + + + YL + ++H ++ NILL Sbjct 413 PNKSLDYFLFDPTKQGQLDWTKRYNIIGGITRGILYLHQDSRLTIIHRDLKASNILLDA- 471 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + + F G+ + + ++ PE + G S+ + D + FG +L Sbjct 472 DMIPKIADFGMARISGIDQSVANTKRIAGTFGYMPPEYVIHGQFSMKS--DVYSFGVLIL 529 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP-QLATLTSQ----------------- 847 EI + ++ ++ E+ RL P +L LT Sbjct 530 EIICGKKNRSFYQADTKAENLVTYVWRLWTNGSPLELVDLTISENCQTEEVIRCIHIALL 589 Query 848 CLTYEPTQRPSFRTILRDLTR 868 C+ +P RP+ TI+ LT Sbjct 590 CVQEDPKDRPNLSTIMMMLTN 610 >sp|Q8IVH8|M4K3_HUMAN Mitogen-activated protein kinase kinase kinase kinase 3 OS=Homo sapiens OX=9606 GN=MAP4K3 PE=1 SV=1 Length=894 Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 56/199 (28%), Positives = 102/199 (51%), Gaps = 14/199 (7%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I+ +G G +G V Y N TGE+ A+K +K + G + + +QEI +++ H +I Sbjct 19 IQRIGSGTYGDV----YKARNVNTGELAAIKVIKLEPG-EDFAVVQQEIIMMKDCKHPNI 73 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 + Y G + + L + ME+ GSL+D Y + Q+ +++ +G+ YLH++ Sbjct 74 VAYFGSYLRRDK--LWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKG 131 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL---KE 1075 +HRD+ N+LL ++ VK+ DFG++ + R+ +W APE ++ Sbjct 132 KMHRDIKGANILLTDNGHVKLADFGVSAQITAT---IAKRKSFIGTPYWMAPEVAAVERK 188 Query 1076 YKFYYASDVWSFGVTLYEL 1094 + D+W+ G+T EL Sbjct 189 GGYNQLCDLWAVGITAIEL 207 Score = 41.2 bits (95), Expect = 0.069, Method: Compositional matrix adjust. Identities = 73/322 (23%), Positives = 122/322 (38%), Gaps = 59/322 (18%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 R Q++ + +G GT +VY+ R + G+ + + Sbjct 10 RNPQEDFELIQRIGSGTYGDVYKAR----------------------NVNTGELAAIKVI 47 Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRR 701 L+P D A+ E +M H ++ G +R + + E+ G L D++ Sbjct 48 KLEPGE-DFAVVQQEII-MMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIY--H 103 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 G + V+++ L YL +K +H ++ G NILL G +KL+D G Sbjct 104 VTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNG-------HVKLADFG 156 Query 762 VG---LGALSREERVERIP-WLAPECLP----GGANSLSTAMDKWGFGATLLEIC----- 808 V +++ + P W+APE GG N L D W G T +E+ Sbjct 157 VSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLC---DLWAVGITAIELAELQPP 213 Query 809 -FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL---- 863 FD P+++ K +F + + LT P +RP+ +L Sbjct 214 MFDLH-PMRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPF 272 Query 864 --RDLTRLQPHNLADVLTVNPD 883 + LTR L D + NPD Sbjct 273 VTQHLTRSLAIELLDKVN-NPD 293 >sp|Q8RY67|WAKLO_ARATH Wall-associated receptor kinase-like 14 OS=Arabidopsis thaliana OX=3702 GN=WAKL14 PE=2 SV=2 Length=708 Score = 80.9 bits (198), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 67/207 (32%), Positives = 101/207 (49%), Gaps = 26/207 (13%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK-----QEIDILRTLY 955 + LG G +G V Y ND E VA+K L+ HR EI +L ++ Sbjct 352 QKLGIGAYGTV--YRGKLQND---EWVAIKRLR------HRDSESLDQVMNEIKLLSSVS 400 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGL--AQLLLFAQQICEGMA 1012 H ++++ GCC +QG+ LV EY+P G+L ++L R GL L A Q + +A Sbjct 401 HPNLVRLLGCCIEQGDP--VLVYEYMPNGTLSEHLQRDRGSGLPWTLRLTVATQTAKAIA 458 Query 1013 YLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH+ HRD+ + N+LLD D K+ DFGL++ + G + Sbjct 459 YLHSSMNPPIYHRDIKSTNILLDYDFNSKVADFGLSRLGMTESSHISTAPQGTPG--YLD 516 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLT 1096 P+ + + SDV+SFGV L E++T Sbjct 517 PQYHQCFHLSDKSDVYSFGVVLAEIIT 543 Score = 55.1 bits (131), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 22/158 (14%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLA 719 L+S VSH +L + G C+ + ++V EY+ +G L L+R+RG +P ++ VA Q A Sbjct 395 LLSSVSHPNLVRLLGCCIEQGDPVLVYEYMPNGTLSEHLQRDRGSGLPWTLRLTVATQTA 454 Query 720 SALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI 776 A++YL N + H ++ NILL + K++D G+ ++ + Sbjct 455 KAIAYLHSSMNPPIYHRDIKSTNILLDYDFNS-------KVADFGLSRLGMTESSHIST- 506 Query 777 PWLAPECLPGGAN-------SLSTAMDKWGFGATLLEI 807 AP+ PG + LS D + FG L EI Sbjct 507 ---APQGTPGYLDPQYHQCFHLSDKSDVYSFGVVLAEI 541 >sp|O15111|IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Homo sapiens OX=9606 GN=CHUK PE=1 SV=2 Length=745 Score = 80.9 bits (198), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 62/206 (30%), Positives = 96/206 (47%), Gaps = 24/206 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V LY + + +A+K+ + + ++R W EI I++ L H +++K Sbjct 21 LGTGGFGNVCLYQHRELDLK----IAIKSCRLELSTKNRERWCHEIQIMKKLNHANVVK- 75 Query 963 KGCCEDQGEKSLQ------LVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMA 1012 C+ E ++ L MEY G LR L P + GL +Q+L I G+ Sbjct 76 --ACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIR 133 Query 1013 YLHAQHYIHRDLAARNVLLDN---DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH IHRDL N++L + + KI D G AK V +G + + + A Sbjct 134 YLHENKIIHRDLKPENIVLQDVGGKIIHKIIDLGYAKDVDQG----SLCTSFVGTLQYLA 189 Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095 PE + + D WSFG ++E + Sbjct 190 PELFENKPYTATVDYWSFGTMVFECI 215 >sp|Q8CFH6|SIK2_MOUSE Serine/threonine-protein kinase SIK2 OS=Mus musculus OX=10090 GN=Sik2 PE=1 SV=1 Length=931 Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 63/196 (32%), Positives = 91/196 (46%), Gaps = 13/196 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG+G+F V L + T VA+K + K+ + +E+ I++ L H HIIK Sbjct 26 LGKGNFAVVKLGRHRTTKTE----VAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIK 81 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020 E + L LV EY G + DYL H + ++ QI + Y H + + Sbjct 82 LYQVMETKS--MLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKVV 139 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDL A N+LLDN+ +KI DFG G G P + APE + ++ Sbjct 140 HRDLKAENLLLDNNMNIKIADFGFGNFFKTGE--LLATWCGSPP--YAAPEVFEGQQYEG 195 Query 1081 AS-DVWSFGVTLYELL 1095 D+WS GV LY L+ Sbjct 196 PQLDIWSMGVVLYVLV 211 Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust. Identities = 48/192 (25%), Positives = 79/192 (41%), Gaps = 19/192 (10%) Query 630 GRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 GR R + V +K++D S D Y +M + H H+ ++ V +VT Sbjct 37 GRHRTTKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVT 96 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 EY ++G + +L G + + Q+ SA+ Y + +VH ++ N+LL Sbjct 97 EYAKNGEIFDYLAN-HGRLNESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLL----- 150 Query 748 AEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGATL 804 + IK++D G G + E P+ APE G +D W G L Sbjct 151 --DNNMNIKIADFGFGNFFKTGELLATWCGSPPYAAPEVFEGQQYE-GPQLDIWSMGVVL 207 Query 805 -LEIC----FDG 811 + +C FDG Sbjct 208 YVLVCGALPFDG 219 >sp|Q8GYQ5|MPK12_ARATH Mitogen-activated protein kinase 12 OS=Arabidopsis thaliana OX=3702 GN=MPK12 PE=1 SV=1 Length=372 Score = 79.0 bits (193), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 65/212 (31%), Positives = 97/212 (46%), Gaps = 21/212 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILR 952 ++Y+ IR +G G G V N TGE VA+K + A +EI +LR Sbjct 38 RKYVPPIRPIGRGACGIVCA----AVNSVTGEKVAIKKIGNAFDNIIDAKRTLREIKLLR 93 Query 953 TLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICE 1009 + HE++I K + + +V E + R ++ Q Q+ Sbjct 94 HMDHENVITIKDIVRPPQRDIFNDVYIVYELMDTDLQRILRSNQTLTSDQCRFLVYQLLR 153 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH---EYYRVREDGDSPVF 1066 G+ Y+H+ + +HRDL NVLL++ +KIGDFGLA+ + EY R Sbjct 154 GLKYVHSANILHRDLRPSNVLLNSKNELKIGDFGLARTTSDTDFMTEYVVTR-------- 205 Query 1067 WY-APECLKEYKFYYAS-DVWSFGVTLYELLT 1096 WY APE L Y A+ D+WS G L E++T Sbjct 206 WYRAPELLLNCSEYTAAIDIWSVGCILGEIMT 237 >sp|Q6C3D7|STE20_YARLI Serine/threonine-protein kinase STE20 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) OX=284591 GN=STE20 PE=3 SV=1 Length=1125 Score = 81.3 bits (199), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 56/208 (27%), Positives = 103/208 (50%), Gaps = 14/208 (7%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DPT ++ +K +G+G G V Y+ G+ VA+K + + P+ + E Sbjct 839 DPTKLYRNLVK----IGQGASGGV-FTAYE---VGSNLSVAIKQMNLEHQPK-KELIINE 889 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +++ H++I+ + G+ L +VMEY+ GSL D + + + +Q+ ++ Sbjct 890 ILVMKDSKHKNIVNFIDSYLHGGD--LWVVMEYMEGGSLTDVVTYNMMTESQIGAVCRET 947 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 G+ +LH++ IHRD+ + NVLL +K+ DFG + E + R G +W Sbjct 948 LLGLQHLHSKGVIHRDIKSDNVLLSMRGEIKLTDFGFCAQINESN-LKRTTMVGTP--YW 1004 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095 APE + ++ D+WS G+ E++ Sbjct 1005 MAPEVVSRKEYGSKVDIWSLGIMSIEMI 1032 Score = 44.7 bits (104), Expect = 0.007, Method: Compositional matrix adjust. Identities = 47/199 (24%), Positives = 80/199 (40%), Gaps = 32/199 (16%) Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 G L V +K ++ H +M H ++ + G + +V EY+E G Sbjct 865 GSNLSVAIKQMNLEHQPKKELIINEILVMKDSKHKNIVNFIDSYLHGGDLWVVMEYMEGG 924 Query 694 PL-DVWLRRERGHVPMAWKMVVAQQLAS-------ALSYLENKNLVHGNVCGRNILLARL 745 L DV + + M+ Q+ + L +L +K ++H ++ N+LL+ Sbjct 925 SLTDV----------VTYNMMTESQIGAVCRETLLGLQHLHSKGVIHRDIKSDNVLLSMR 974 Query 746 GLAEGTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 G IKL+D G + L R V W+APE + + +D W G Sbjct 975 G-------EIKLTDFGFCAQINESNLKRTTMVGTPYWMAPEVV--SRKEYGSKVDIWSLG 1025 Query 802 ATLLEICFDGEAPLQSRSP 820 +E+ +GE P + SP Sbjct 1026 IMSIEM-IEGEPPYLNESP 1043 >sp|Q9LDI3|CIPKO_ARATH CBL-interacting serine/threonine-protein kinase 24 OS=Arabidopsis thaliana OX=3702 GN=CIPK24 PE=1 SV=1 Length=446 Score = 79.7 bits (195), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 60/199 (30%), Positives = 102/199 (51%), Gaps = 13/199 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEH 958 R +GEG F KV N TG+ VA+K + ++R K+EI I++ + H + Sbjct 15 RTIGEGTFAKVKF----ARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPN 70 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ 1017 I++ + + +V+E+V G L D + + + ++ + QQ+ + +A+ H + Sbjct 71 IVRLYEVLASPSK--IYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCK 128 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 HRDL N+LLD + +K+ DFGL+ EG E +R +P + APE L Sbjct 129 GVYHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVEL--LRTTCGTP-NYVAPEVLSGQG 185 Query 1078 FY-YASDVWSFGVTLYELL 1095 + A+D+WS GV L+ +L Sbjct 186 YDGSAADIWSCGVILFVIL 204 Score = 37.0 bits (84), Expect = 1.0, Method: Compositional matrix adjust. Identities = 59/219 (27%), Positives = 93/219 (42%), Gaps = 31/219 (14%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQL 718 S+M V H ++ ++ V + +V E+V G L D + + R + K QQL Sbjct 61 SIMKIVRHPNIVRLYEVLASPSKIYIVLEFVTGGELFDRIVHKGRLEESESRKYF--QQL 118 Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI-- 776 A+++ K + H ++ N+LL T+ +K+SD GL AL +E VE + Sbjct 119 VDAVAHCHCKGVYHRDLKPENLLL-------DTNGNLKVSD--FGLSALP-QEGVELLRT 168 Query 777 -----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 ++APE L G S A D W G L + G P S ++ Y R+ Sbjct 169 TCGTPNYVAPEVLSGQGYDGSAA-DIWSCGVILF-VILAGYLPF---SETDLPGLY-RKI 222 Query 832 RLPEPSCP-----QLATLTSQCLTYEPTQRPSFRTILRD 865 E SCP ++ L + L P R + I +D Sbjct 223 NAAEFSCPPWFSAEVKFLIHRILDPNPKTRIQIQGIKKD 261 >sp|Q21029|NSY1_CAEEL Mitogen-activated protein kinase kinase kinase nsy-1 OS=Caenorhabditis elegans OX=6239 GN=nsy-1 PE=1 SV=4 Length=1498 Score = 81.3 bits (199), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 75/272 (28%), Positives = 125/272 (46%), Gaps = 29/272 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G +G V Y + T + VK ++ + + +EI + TL H +I++Y Sbjct 670 LGKGTYGTV----YAARDMDTQRQIVVKEIEVKYDEEVQP-LMEEISLHSTLCHANIVQY 724 Query 963 KGC---CEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQ 1017 GC +D + ME+VP GSL L + + + +QI EG+ YLH Sbjct 725 LGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKYLHEL 784 Query 1018 HYIHRDLAARNVLLDN-DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRD+ NVL++ + KI DFG K + + V E + + APE + Sbjct 785 KIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNP---VTETFTGTLQYMAPEVIDHG 841 Query 1077 KFYYA--SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + Y +D+WSFG T+ E+ T PP F+E+ Q + R+ Sbjct 842 QRGYGAPADIWSFGCTMVEMAT-----GRPP--FVEM---QNPQAAMFRVGMF---KTHP 888 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 P P + + + +K+C+ EA RP+ ++L+ Sbjct 889 PIPTEITEKCRNFIKSCFLPEACDRPSAKDLL 920 Score = 57.8 bits (138), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 56/250 (22%), Positives = 99/250 (40%), Gaps = 22/250 (9%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN-----I 684 RD + ++V+K ++ + + E SL S + H ++ G + G + + Sbjct 681 ARDMDTQRQIVVKEIEVKYDEEVQPLMEEISLHSTLCHANIVQYLGCDLVGKDGSNDHFL 740 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 + E+V G L LR + G + +Q+ L YL +VH ++ G N+L+ Sbjct 741 IFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLV-- 798 Query 745 LGLAEGTSPFIKLSDPGV-----GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 S K+SD G GL ++ E + ++APE + G D W Sbjct 799 ----NTYSGVCKISDFGTCKRLAGLNPVT-ETFTGTLQYMAPEVIDHGQRGYGAPADIWS 853 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHF----YQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855 FG T++E+ G P + F ++ +P + C E Sbjct 854 FGCTMVEMA-TGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACD 912 Query 856 RPSFRTILRD 865 RPS + +L+D Sbjct 913 RPSAKDLLQD 922 >sp|Q54GY6|KXCA_DICDI Kinase and exchange factor for Rac A OS=Dictyostelium discoideum OX=44689 GN=kxcA PE=3 SV=1 Length=1311 Score = 81.3 bits (199), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 77/316 (24%), Positives = 138/316 (44%), Gaps = 69/316 (22%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G+FG V Y G VA+K + + P + ++E+ LR + H ++ + Sbjct 24 IGKGNFGCVYRGNY------LGVEVAIKQIPSFDDPDYCKYTEREVKALRYIRHPFVVHF 77 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 G C + E L+ E++ LR YL P+ L+++ + A + + +LH+++ Sbjct 78 FGAC--KHESGFYLITEFIEGLDLRRYLKSVPKPPKWLSRVNI-ALGVAKTFLFLHSKNL 134 Query 1020 IHRDLAARNVLLDNDR-LVKIGDFGLAKAVPEGHEY------------------------ 1054 +HRDL ++N+LLD R +K+ DFG A+ G +Y Sbjct 135 LHRDLKSKNILLDISRNQIKLCDFGFARV---GSQYSNGSDSSSSEDESDSECVNGAAGG 191 Query 1055 ----------------YRVREDG--DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 YR+R +P F PE L + K+ ++ DV+SFG+ EL+T Sbjct 192 GGDDVYKNNGNGKPANYRLRRMSICGTPSFM-PPEILLQQKYDWSVDVFSFGILCTELIT 250 Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156 + + +Q + + EL +P P+ CP + Y L C + Sbjct 251 LKRPGKDYWVR-------SQNNGFDINIEEL---NVNIPSPNDCPIQFYDLALKCCSYKH 300 Query 1157 SFRPTFENLIPILKTV 1172 + RP F ++ IL+++ Sbjct 301 TNRPMFSTIVTILESI 316 >sp|P34556|CDK1_CAEEL Cyclin-dependent kinase 1 OS=Caenorhabditis elegans OX=6239 GN=cdk-1 PE=1 SV=1 Length=332 Score = 78.6 bits (192), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 64/218 (29%), Positives = 101/218 (46%), Gaps = 26/218 (12%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEI 948 +V+ K+ +GEG +G V Y N T MVA+K ++ + + S +EI Sbjct 15 SVYTLNDFTKLEKIGEGTYGVV----YKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREI 70 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR--------DYLPRHSIGLAQL 1000 +L+ L H +++ + E L L+ E++ R +YLP L L Sbjct 71 SLLKELQHPNVVGLEAVI--MQENRLFLIFEFLSFDLKRYMDQLGKDEYLP-----LETL 123 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 + QI + M + H + IHRDL +N+L+DN+ +K+ DFGLA+A+ Y Sbjct 124 KSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAIGIPIRVYT---- 179 Query 1061 GDSPVFWY-APECLKEYKFY-YASDVWSFGVTLYELLT 1096 + WY APE L + Y D+WS G E+ T Sbjct 180 HEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEMAT 217 >sp|Q6PDN3|MYLK_MOUSE Myosin light chain kinase, smooth muscle OS=Mus musculus OX=10090 GN=Mylk PE=1 SV=3 Length=1941 Score = 81.3 bits (199), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 71/256 (28%), Positives = 112/256 (44%), Gaps = 36/256 (14%) Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911 E + P + D +P +TVN + SD +R LG G FG+V Sbjct 1448 EKPEEPKDEVEVSDDDEKEPEVDYRTVTVNTEQKVSDVYDIEER-------LGSGKFGQV 1500 Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 + TG++ A K KA + + +QEI I+ L+H +++ C D E Sbjct 1501 ----FRLVEKKTGKIWAGKFFKAYSA-KEKDNIRQEISIMNCLHHPKLVQ----CVDAFE 1551 Query 972 KSLQLVM--EYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQHYIHRDLAAR 1027 + +VM E V G L + + L + + + +QI EG+ Y+H Q +H DL Sbjct 1552 EKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPE 1611 Query 1028 NVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WYAPECLKEYKFYY 1080 N++ N +K+ DFGLA+ R+ G V + APE + Y Sbjct 1612 NIMCVNKTGTRIKLIDFGLAR---------RLENAGSLKVLFGTPEFVAPEVINYEPIGY 1662 Query 1081 ASDVWSFGVTLYELLT 1096 A+D+WS GV Y L++ Sbjct 1663 ATDMWSIGVICYILVS 1678 >sp|Q62925|M3K1_RAT Mitogen-activated protein kinase kinase kinase 1 OS=Rattus norvegicus OX=10116 GN=Map3k1 PE=1 SV=1 Length=1493 Score = 81.3 bits (199), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 63/244 (26%), Positives = 118/244 (48%), Gaps = 25/244 (10%) Query 868 RLQPHNLADVLTVNPDSP--------ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919 +LQ N D++ + D+P A++P +LK + +G G F CY Sbjct 1188 QLQVENGEDIIIIQQDTPETLPGHTKANEPYREDTEWLKG-QQIGLGAFSS----CYQAQ 1242 Query 920 NDGTGEMVAVKAL---KADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGC-CEDQGEKS 973 + GTG ++AVK + + Q ++EI ++ L H +II+ G CE + + Sbjct 1243 DVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCE---KSN 1299 Query 974 LQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032 L +E++ S+ L ++ +++ + +Q+ G++YLH IHRD+ N+L+D Sbjct 1300 YNLFIEWMAGASVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLID 1359 Query 1033 ND-RLVKIGDFG-LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 + + ++I DFG A+ +G + + + APE L+ ++ + DVWS G Sbjct 1360 STGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCA 1419 Query 1091 LYEL 1094 + E+ Sbjct 1420 IIEM 1423 Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust. Identities = 52/227 (23%), Positives = 94/227 (41%), Gaps = 16/227 (7%) Query 648 HHDIALAFYETASLMSQVSHTHLAFVHG-VCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 ++ A E +MS ++H ++ + G C + N+ + E++ G L + G Sbjct 1265 QEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFI-EWMA-GASVAHLLSKYGAF 1322 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF---IKLSDPGVG 763 + + +QL LSYL ++H +V G N+L+ G + F +L+ G G Sbjct 1323 KESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTG 1382 Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE- 822 G + + + I ++APE L G + D W G ++E+ + P + S Sbjct 1383 AGEF-QGQLLGTIAFMAPEVLRG--QQYGRSCDVWSVGCAIIEMAC-AKPPWNAEKHSNH 1438 Query 823 -----KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 K +P P L + +CL +P RP R +L+ Sbjct 1439 LALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLK 1485 >sp|Q5REX1|SIK2_PONAB Serine/threonine-protein kinase SIK2 OS=Pongo abelii OX=9601 GN=SIK2 PE=2 SV=1 Length=925 Score = 80.9 bits (198), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 63/196 (32%), Positives = 91/196 (46%), Gaps = 13/196 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG+G+F V L + T VA+K + K+ + +E+ I++ L H HIIK Sbjct 26 LGKGNFAVVKLGRHRITKTE----VAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIK 81 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020 E + L LV EY G + DYL H + ++ QI + Y H + + Sbjct 82 LYQVMETKS--MLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIV 139 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDL A N+LLDN+ +KI DF G R G P + APE + ++ Sbjct 140 HRDLKAENLLLDNNMNIKIADFSFGNFFKSGELLATWR--GSPP--YAAPEVFEGQQYEG 195 Query 1081 AS-DVWSFGVTLYELL 1095 D+WS GV LY L+ Sbjct 196 PQLDIWSMGVVLYVLV 211 Score = 45.4 bits (106), Expect = 0.004, Method: Compositional matrix adjust. Identities = 48/192 (25%), Positives = 78/192 (41%), Gaps = 19/192 (10%) Query 630 GRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 GR R + V +K++D S D Y +M + H H+ ++ V +VT Sbjct 37 GRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVT 96 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 EY ++G + +L G + + Q+ SA+ Y + +VH ++ N+LL Sbjct 97 EYAKNGEIFDYLAN-HGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLL----- 150 Query 748 AEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGATL 804 + IK++D G S E P+ APE G +D W G L Sbjct 151 --DNNMNIKIADFSFGNFFKSGELLATWRGSPPYAAPEVFEGQQYE-GPQLDIWSMGVVL 207 Query 805 -LEIC----FDG 811 + +C FDG Sbjct 208 YVLVCGALPFDG 219 >sp|Q7X8C5|WAKLB_ARATH Wall-associated receptor kinase-like 2 OS=Arabidopsis thaliana OX=3702 GN=WAKL2 PE=2 SV=1 Length=748 Score = 80.5 bits (197), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 60/181 (33%), Positives = 87/181 (48%), Gaps = 14/181 (8%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 G +VAVK KA + E+ +L + H +I+K GCC + + LV E+VP Sbjct 438 GRIVAVKRSKA-VDEDRVEEFINEVVVLAQINHRNIVKLLGCCLET--EVPVLVYEFVPN 494 Query 984 GSL----RDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI---HRDLAARNVLLDNDRL 1036 G L D +++ L A +I ++YLH+ HRD+ N+LLD Sbjct 495 GDLCKRLHDESDDYTMTWEVRLHIAIEIAGALSYLHSAASFPIYHRDIKTTNILLDERNR 554 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA-PECLKEYKFYYASDVWSFGVTLYELL 1095 K+ DFG +++V + + G F Y PE + KF SDV+SFGV L ELL Sbjct 555 AKVSDFGTSRSVTIDQTHLTTQVAG---TFGYVDPEYFQSSKFTEKSDVYSFGVVLVELL 611 Query 1096 T 1096 T Sbjct 612 T 612 Score = 52.8 bits (125), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 70/305 (23%), Positives = 122/305 (40%), Gaps = 65/305 (21%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LGQG + VY+G L V GR V +K D Sbjct 422 LGQGGQGTVYKGML-------------------VDGR------IVAVKRSKAVDEDRVEE 456 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KM 712 F +++Q++H ++ + G C+ ++V E+V +G L L E M W ++ Sbjct 457 FINEVVVLAQINHRNIVKLLGCCLETEVPVLVYEFVPNGDLCKRLHDESDDYTMTWEVRL 516 Query 713 VVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 +A ++A ALSYL + + H ++ NILL A K+SD G Sbjct 517 HIAIEIAGALSYLHSAASFPIYHRDIKTTNILLDERNRA-------KVSDFGTSRSVTID 569 Query 770 EERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + + ++ PE ++ + D + FG L+E+ GE P SR SE+ Sbjct 570 QTHLTTQVAGTFGYVDPEYFQ--SSKFTEKSDVYSFGVVLVEL-LTGEKP-SSRVRSEEN 625 Query 825 -----HFYQ--RQHRLPE------------PSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 HF + +++R+ + +A L +CL + +RP+ R + + Sbjct 626 RGLAAHFVEAVKENRVLDIVDDRIKDECNMDQVMSVANLARRCLNRKGKKRPNMREVSIE 685 Query 866 LTRLQ 870 L ++ Sbjct 686 LEMIR 690 >sp|Q39202|RLK1_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase RLK1 OS=Arabidopsis thaliana OX=3702 GN=RLK1 PE=2 SV=2 Length=832 Score = 80.5 bits (197), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 78/291 (27%), Positives = 127/291 (44%), Gaps = 16/291 (5%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +LG G FG V Y G+ VAVK L + +K E+ ++ ++H+++++ Sbjct 536 ELGRGAFGIV-YKGYLEVAGGSEVTVAVKKLDR-LDLDNEKEFKNEVKVIGQIHHKNLVR 593 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH--- 1015 G C + +S +V E++P G+L ++L PR S + + A I G+ YLH Sbjct 594 LIGFCNEG--QSQMIVYEFLPQGTLANFLFRRPRPSWEDRKNIAVA--IARGILYLHEEC 649 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 ++ IH D+ +N+LLD +I DFGLAK + Y G + APE + Sbjct 650 SEQIIHCDIKPQNILLDEYYTPRISDFGLAKLLLMNQTYTLTNIRGTKG--YVAPEWFRN 707 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 DV+S+GV L E++ C + LI A RL +L E Sbjct 708 SPITSKVDVYSYGVMLLEIV--CCKKAVDLEDNVILINWAYDCFRQGRLEDLTEDDSEAM 765 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 + + C + E RP N+ +L+ V + + PS +S Sbjct 766 NDMETVERYVKIAIWCIQEEHGMRPNMRNVTQMLEGVIQVFDPPNPSPYST 816 Score = 51.2 bits (121), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 61/252 (24%), Positives = 108/252 (43%), Gaps = 45/252 (18%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 A + LNL ++ + + LG+G VY+G L V G Sbjct 509 ATTTANELNLRVFTYGELAEATRDFTEELGRGAFGIVYKGYLEVAG-------------- 554 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 G E+ V +K LD D F ++ Q+ H +L + G C G ++V Sbjct 555 -------GSEVTVAVKKLDRLDLDNEKEFKNEVKVIGQIHHKNLVRLIGFCNEGQSQMIV 607 Query 687 TEYVEHGPLDVWL-RRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNI 740 E++ G L +L RR R +W + +A +A + YL ++ ++H ++ +NI Sbjct 608 YEFLPQGTLANFLFRRPRP----SWEDRKNIAVAIARGILYLHEECSEQIIHCDIKPQNI 663 Query 741 LLARLGLAEGTSPFIKLSDPGVG-LGALSREERVERI----PWLAPECLPGGANSLSTAM 795 L L E +P ++SD G+ L +++ + I ++APE +++ + Sbjct 664 L-----LDEYYTP--RISDFGLAKLLLMNQTYTLTNIRGTKGYVAPEWFRNSP--ITSKV 714 Query 796 DKWGFGATLLEI 807 D + +G LLEI Sbjct 715 DVYSYGVMLLEI 726 >sp|P50528|PLO1_SCHPO Serine/threonine-protein kinase plo1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=plo1 PE=1 SV=1 Length=683 Score = 80.5 bits (197), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 74/282 (26%), Positives = 123/282 (44%), Gaps = 33/282 (12%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ--E 947 +F+ RY +GEG F + C+ D G + A K + ++ K E Sbjct 38 NIFYTRY----DCIGEGGFAR----CFR-VKDNYGNIYAAKVIAKRSLQNDKTKLKLFGE 88 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006 I + +++ H +I+ + C ED ++ L++E SL + L R + ++ Q Sbjct 89 IKVHQSMSHPNIVGFIDCFEDST--NIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQ 146 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I + Y+H + IHRDL N++LD VKIGDFGLA + + E R +P Sbjct 147 ILGALKYMHKKRVIHRDLKLGNIMLDESNNVKIGDFGLAALLMDDEE--RKMTICGTPN- 203 Query 1067 WYAPECLKEYK--FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 + APE L K + D+WS GV +Y LL PP + E+ T+ R Sbjct 204 YIAPEILFNSKEGHSFEVDLWSAGVVMYALLI-----GKPPFQDKEV-------KTIYR- 250 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 ++ P E L+ + + S RP+ ++++ Sbjct 251 -KIKANSYSFPSNVDISAEAKDLISSLLTHDPSIRPSIDDIV 291 Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 51/198 (26%), Positives = 86/198 (43%), Gaps = 23/198 (12%) Query 677 CVRGPENI-MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNV 735 C NI ++ E EH L + L R+R + + Q+ AL Y+ K ++H Sbjct 106 CFEDSTNIYLILELCEHKSL-MELLRKRKQLTEPEVRYLMMQILGALKYMHKKRVIH--- 161 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI----PWLAPECLPGGANSL 791 R++ L + L E + +K+ D G+ + EER I ++APE L Sbjct 162 --RDLKLGNIMLDESNN--VKIGDFGLAALLMDDEERKMTICGTPNYIAPEILFNSKEGH 217 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ--RQHRLPEPSCPQLAT----LT 845 S +D W G + + G+ P Q + E + Y+ + + PS ++ L Sbjct 218 SFEVDLWSAGVVMYALLI-GKPPFQDK---EVKTIYRKIKANSYSFPSNVDISAEAKDLI 273 Query 846 SQCLTYEPTQRPSFRTIL 863 S LT++P+ RPS I+ Sbjct 274 SSLLTHDPSIRPSIDDIV 291 >sp|Q52EB3|ATG1_PYRO7 Serine/threonine-protein kinase ATG1 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507 GN=ATG1 PE=1 SV=1 Length=982 Score = 80.9 bits (198), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 76/317 (24%), Positives = 128/317 (40%), Gaps = 75/317 (24%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHII 960 ++G+G F +V Y + +G VA+K+++ A + + EI+IL+TL H HI+ Sbjct 24 EIGKGSFAQV----YMGKHKVSGAAVAIKSVELARLNKKLKENLYGEINILKTLRHPHIV 79 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSL--------------------RDYLPRHSIGLAQL 1000 C E + L+MEY LG L R Y + GL ++ Sbjct 80 ALHDCVESATH--INLMMEYCELGDLSLFIKKREKLSTNPATHDMARKYPNVPNSGLNEV 137 Query 1001 LL--FAQQICEGMAYLHAQHYIHRDLAARNVLL-------------------DNDRLV-- 1037 ++ F +Q+ + +L + +HRD+ +N+LL D LV Sbjct 138 VIRHFLKQLSSALKFLRESNLVHRDVKPQNLLLLPSPEFREVNKLARPILTASQDSLVPV 197 Query 1038 ---------KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 K+ DFG A+ +P + E + APE L+ ++ +D+WS G Sbjct 198 AGLASLPMLKLADFGFARVLPSTS----LAETLCGSPLYMAPEILRYERYDAKADLWSVG 253 Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148 L+E++ PP + A + +LR E E + PR E+ L Sbjct 254 TVLFEMIVG-----RPPFR-------ASNHVELLRKIEAAEDVIKFPRETTISSEMKGLT 301 Query 1149 KNCWETEASFRPTFENL 1165 + + R +FEN Sbjct 302 RALLKRNPVERISFENF 318 Score = 40.4 bits (93), Expect = 0.13, Method: Compositional matrix adjust. Identities = 75/323 (23%), Positives = 126/323 (39%), Gaps = 86/323 (27%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 + +G+G+ VY G+ +V G+ V +K ++ + + Sbjct 23 AEIGKGSFAQVYMGKHKVSGAA------------------------VAIKSVELARLNKK 58 Query 653 LA--FYETASLMSQVSHTHLAFVHGVCVRGPENI-MVTEYVEHGPLDVWLR--------- 700 L Y +++ + H H+ +H CV +I ++ EY E G L ++++ Sbjct 59 LKENLYGEINILKTLRHPHIVALHD-CVESATHINLMMEYCELGDLSLFIKKREKLSTNP 117 Query 701 ------RERGHVPMAWKMVVA-----QQLASALSYLENKNLVHGNVCGRNIL-------- 741 R+ +VP + V +QL+SAL +L NLVH +V +N+L Sbjct 118 ATHDMARKYPNVPNSGLNEVVIRHFLKQLSSALKFLRESNLVHRDVKPQNLLLLPSPEFR 177 Query 742 ----LAR-------------LGLAEGTSPFIKLSDPGVG--LGALSREERVERIP-WLAP 781 LAR GLA + P +KL+D G L + S E + P ++AP Sbjct 178 EVNKLARPILTASQDSLVPVAGLA--SLPMLKLADFGFARVLPSTSLAETLCGSPLYMAP 235 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE---KEHFYQRQHRLPEPSC 838 E L D W G L E+ G P ++ + E K + + P + Sbjct 236 EIL--RYERYDAKADLWSVGTVLFEMIV-GRPPFRASNHVELLRKIEAAEDVIKFPRETT 292 Query 839 --PQLATLTSQCLTYEPTQRPSF 859 ++ LT L P +R SF Sbjct 293 ISSEMKGLTRALLKRNPVERISF 315 >sp|A9TF79|SRK2A_PHYPA Serine/threonine-protein kinase SRK2A OS=Physcomitrium patens OX=3218 GN=SRK2A PE=1 SV=1 Length=349 Score = 78.6 bits (192), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 79/231 (34%), Positives = 114/231 (49%), Gaps = 27/231 (12%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 H RY + ++D+G G+FG L + T E+VAVK ++ G + ++EI R Sbjct 9 HDRY-ELVKDIGSGNFGVARLM----RDKKTRELVAVKYIER--GEKIDENVQREIINHR 61 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009 +L H +I+++K L +VMEY G L + + R S A+ F QQ+ Sbjct 62 SLRHPNIVRFKEVM--LTPTHLAIVMEYAAGGELFERICNAGRFSEDEARF--FFQQLIS 117 Query 1010 GMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G++Y H+ HRDL N LLD RL KI DFG +K+ + + + +P Sbjct 118 GVSYCHSMQICHRDLKLENTLLDGSPAPRL-KICDFGYSKS---SLLHSQPKSTVGTPA- 172 Query 1067 WYAPECL--KEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLELIG 1113 + APE L KEY A DVWS GVTLY +L + P P F + IG Sbjct 173 YIAPEVLSKKEYDGKIA-DVWSCGVTLYVMLVGAYPFEDPEDPRNFRKTIG 222 >sp|P34101|FHKC_DICDI Probable serine/threonine-protein kinase fhkC OS=Dictyostelium discoideum OX=44689 GN=fhkC PE=3 SV=2 Length=595 Score = 80.1 bits (196), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 74/220 (34%), Positives = 103/220 (47%), Gaps = 20/220 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL---KADCGPQHRSGWKQEIDILRTLYHEHI 959 LG G+F V L TG A+K + K + + E+++L + H++I Sbjct 224 LGTGNFASVRL----GVEKETGNKYAIKIIDKKKMSMTSKRKDSLMDEVNVLTKVKHQNI 279 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I K E Q K+L LV+E V G L D + +Q+C+ + YLH+ Sbjct 280 ISIKEVFETQ--KNLYLVLELVTGGELFDKIVSERKFQEDTCRYILKQLCDSVRYLHSNG 337 Query 1019 YIHRDLAARNVLLD--NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK-- 1074 HRDL N+LL N L+KI DFGL++A+ EG Y + +P + APE L Sbjct 338 IAHRDLKPENILLATPNSFLLKISDFGLSRAMDEGT-YMKTM--CGTPQY-VAPEILTKG 393 Query 1075 EYKFYYAS-DVWSFGVTLYELLTHCDSSQSPPTK-FLELI 1112 E + Y S D+WS GV Y LL P TK F E I Sbjct 394 EREGYGKSVDLWSIGVITYILLCGFPPFGDPQTKDFFEKI 433 >sp|Q8N5S9|KKCC1_HUMAN Calcium/calmodulin-dependent protein kinase kinase 1 OS=Homo sapiens OX=9606 GN=CAMKK1 PE=1 SV=2 Length=505 Score = 79.7 bits (195), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 50/150 (33%), Positives = 79/150 (53%), Gaps = 6/150 (4%) Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ 1005 QEI IL+ L H +++K +D E +L LV + + G + + Q L+ + Sbjct 198 QEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFSEEQARLYLR 257 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 + G+ YLH Q +HRD+ N+LL +D VKI DFG++ EG++ ++ +P Sbjct 258 DVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF-EGND-AQLSSTAGTPA 315 Query 1066 FWYAPECLKEYKFYY---ASDVWSFGVTLY 1092 F APE + + + A DVW+ GVTLY Sbjct 316 FM-APEAISDSGQSFSGKALDVWATGVTLY 344 >sp|Q9LUL4|SRF7_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 7 OS=Arabidopsis thaliana OX=3702 GN=SRF7 PE=1 SV=1 Length=717 Score = 80.5 bits (197), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 73/278 (26%), Positives = 130/278 (47%), Gaps = 41/278 (15%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-WKQEIDILRTLYHEHIIK 961 LGEG FG+V ++ G+++AVK + + P + + + + + L HE++ K Sbjct 425 LGEGTFGRVYRAQFE-----DGKVLAVKKIDSSALPTDTADDFTEIVSKIAHLDHENVTK 479 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------------PRHSI--GLAQLLLFAQQ 1006 G C + G+ +V E+ GSL D+L PR I G A+ L + + Sbjct 480 LDGYCSEHGQH--LVVYEFHRNGSLHDFLHLAEEESKPLIWNPRVKIALGTARALEYLHE 537 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 +C + +H+++ + N+LLD++ + D GLA +P +E ++G Sbjct 538 VC-------SPSIVHKNIKSANILLDSELNPHLSDSGLASFLPTANELLNQNDEG----- 585 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQM-TVL 1122 + APE ++ SDV+SFGV + ELLT DS++S + L+ A Q+ + Sbjct 586 YSAPETSMSGQYSLKSDVYSFGVVMLELLTGRKPFDSTRSRSEQ--SLVRWATPQLHDID 643 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 L ++++ + P K ++ C + E FRP Sbjct 644 ALGKMVDPALKGLYPVKSLSRFADVIALCVQPEPEFRP 681 >sp|Q9DG98|CDK1_ORYLU Cyclin-dependent kinase 1 OS=Oryzias luzonensis OX=104659 GN=cdk1 PE=2 SV=1 Length=303 Score = 77.8 bits (190), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 66/215 (31%), Positives = 109/215 (51%), Gaps = 25/215 (12%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957 KI +GEG +G V Y + TG++VA+K ++ + + S +E+ +L+ L H Sbjct 6 KIEKIGEGTYGVV----YKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLL--FAQQICEGMAY 1013 ++++ E L L+ E++ + L+ YL G + +L+ + QI EG+ + Sbjct 62 NVVRLLDVL--MQESRLYLIFEFLSM-DLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWYAPE 1071 H + +HRDL +N+L+DN ++K+ DFGLA+A VP RV +++ APE Sbjct 119 CHRRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVP-----VRVYTHEVVTLWYRAPE 173 Query 1072 C-LKEYKFYYASDVWSFGVTLYELLT-----HCDS 1100 L ++ DVWS G EL T H DS Sbjct 174 VLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDS 208 >sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1 Length=1235 Score = 80.9 bits (198), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 60/205 (29%), Positives = 99/205 (48%), Gaps = 23/205 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I +LG+G FGKV Y N T + A K + + + EIDIL + H +I Sbjct 37 IGELGDGAFGKV----YKAQNKETSVLAAAKVIDTK-SEEELEDYMVEIDILASCDHPNI 91 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQ 1017 +K E +L +++E+ G++ + + +Q+ + +Q + + YLH Sbjct 92 VKLLDAF--YYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDN 149 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV---FWYAPECL- 1073 IHRDL A N+L D +K+ DFG++ + R + DS + +W APE + Sbjct 150 KIIHRDLKAGNILFTLDGDIKLADFGVS------AKNTRTIQRRDSFIGTPYWMAPEVVM 203 Query 1074 ----KEYKFYYASDVWSFGVTLYEL 1094 K+ + Y +DVWS G+TL E+ Sbjct 204 CETSKDRPYDYKADVWSLGITLIEM 228 Score = 40.4 bits (93), Expect = 0.12, Method: Compositional matrix adjust. Identities = 31/103 (30%), Positives = 44/103 (43%), Gaps = 14/103 (14%) Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG---ALSR 769 VV +Q AL+YL + ++H ++ NIL G IKL+D GV + R Sbjct 134 VVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDG-------DIKLADFGVSAKNTRTIQR 186 Query 770 EERVERIP-WLAPE---CLPGGANSLSTAMDKWGFGATLLEIC 808 + P W+APE C D W G TL+E+ Sbjct 187 RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMA 229 >sp|Q21734|KS6A1_CAEEL Putative ribosomal protein S6 kinase alpha-1 OS=Caenorhabditis elegans OX=6239 GN=rskn-1 PE=3 SV=4 Length=784 Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 61/205 (30%), Positives = 103/205 (50%), Gaps = 10/205 (5%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRT 953 R + ++ LG+G FGKV L D +G + A+K LK A + R K E +IL Sbjct 102 RQFELLKVLGQGSFGKVFLVRKVRGRD-SGHVYAMKVLKKATLKVRDRQRTKLERNILAH 160 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ-LLLFAQQICEGMA 1012 + H I+K + +G+ L L+++++ G L L + + + + ++ + Sbjct 161 ISHPFIVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALE 218 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK-AVPEGHEYYRVREDGDSPVFWYAPE 1071 +LH+ ++RDL N+LLD D +K+ DFGL+K A+ + Y V + APE Sbjct 219 HLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFC----GTVEYMAPE 274 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 + A+D WS GV ++E+LT Sbjct 275 VINRRGHSMAADFWSLGVLMFEMLT 299 Score = 67.8 bits (164), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 26/191 (14%) Query 946 QEIDIL-RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGL-AQLLL 1002 +E+DIL R +H+ ++K ED E ++ ++ E G L D L + S+G ++ Sbjct 494 EEVDILLRHSHHQFVVKLFDVYED--ETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAA 551 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLL---DND-RLVKIGDFGLAKAVPEGHEYYRVR 1058 + + YLH+Q HRDL A N+L D D ++I DFG AK Sbjct 552 IMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRA-------- 603 Query 1059 EDGD--SPVF---WYAPECLKEYKFYYASDVWSFGVTLYELLTHCD----SSQSPPTKFL 1109 E+G +P + + APE L++ + + DVWS GV L+ +LT C P + L Sbjct 604 ENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQIL 663 Query 1110 ELIGIAQGQMT 1120 + +G + MT Sbjct 664 QRVGDGKISMT 674 >sp|G4N6Z6|MKK2_PYRO7 Mitogen-activated protein kinase kinae MKK2 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507 GN=MKK2 PE=1 SV=1 Length=527 Score = 79.7 bits (195), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 54/181 (30%), Positives = 83/181 (46%), Gaps = 9/181 (5%) Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 G + A+K + A+ P + +E+D EHI +Y G ED ++ + ME+ Sbjct 248 GGKTVFALKVITANPDPDVKKQIMRELDFNIQCASEHICRYYGAFEDPSTATISIAMEFC 307 Query 982 PLGSLRDYLPR-----HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036 GSL G L A+ + G+ YL+++ IHRD+ N+LL + Sbjct 308 EGGSLDSIYKEVKRLGGRTGEKVLGKIAEGVLRGLTYLNSKKIIHRDIKPSNILLCRNGD 367 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 VK+ DFG++ E G S ++ APE + + SDVWS GVTL E+ Sbjct 368 VKLCDFGVSGDFGTKGEANTFI--GTS--YYMAPERITGQSYTITSDVWSTGVTLLEVAQ 423 Query 1097 H 1097 H Sbjct 424 H 424 Score = 44.3 bits (103), Expect = 0.007, Method: Compositional matrix adjust. Identities = 46/181 (25%), Positives = 78/181 (43%), Gaps = 22/181 (12%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT---EYVEHG 693 L+V+ DP D+ Q + H+ +G P ++ E+ E G Sbjct 255 LKVITANPDP---DVKKQIMRELDFNIQCASEHICRYYG-AFEDPSTATISIAMEFCEGG 310 Query 694 PLDVW---LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 LD ++R G +A+ + L+YL +K ++H ++ NILL R G Sbjct 311 SLDSIYKEVKRLGGRTGEKVLGKIAEGVLRGLTYLNSKKIIHRDIKPSNILLCRNG---- 366 Query 751 TSPFIKLSDPGVGLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +KL D GV ++ E I ++APE + G + ++++ D W G TLLE+ Sbjct 367 ---DVKLCDFGVSGDFGTKGEANTFIGTSYYMAPERITGQSYTITS--DVWSTGVTLLEV 421 Query 808 C 808 Sbjct 422 A 422 >sp|Q9DGD3|CDK1_ORYLA Cyclin-dependent kinase 1 OS=Oryzias latipes OX=8090 GN=cdk1 PE=2 SV=1 Length=303 Score = 77.8 bits (190), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 66/215 (31%), Positives = 109/215 (51%), Gaps = 25/215 (12%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957 KI +GEG +G V Y + TG++VA+K ++ + + S +E+ +L+ L H Sbjct 6 KIEKIGEGTYGVV----YKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLL--FAQQICEGMAY 1013 ++++ E L L+ E++ + L+ YL G + +L+ + QI EG+ + Sbjct 62 NVVRLLDVL--MQESRLYLIFEFLSM-DLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWYAPE 1071 H + +HRDL +N+L+DN ++K+ DFGLA+A VP RV +++ APE Sbjct 119 CHRRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVP-----VRVYTHEVVTLWYRAPE 173 Query 1072 C-LKEYKFYYASDVWSFGVTLYELLT-----HCDS 1100 L ++ DVWS G EL T H DS Sbjct 174 VLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDS 208 >sp|Q95KV1|IKKA_BOVIN Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Bos taurus OX=9913 GN=CHUK PE=1 SV=1 Length=740 Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 62/206 (30%), Positives = 95/206 (46%), Gaps = 24/206 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V LY + + +A+K+ + + ++R W EI I++ L H +++K Sbjct 21 LGTGGFGNVCLYQHRELDLK----IAIKSCRLELSTKNRERWCHEIQIMKKLNHANVVK- 75 Query 963 KGCCEDQGEKSLQ------LVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMA 1012 C+ E + L MEY G LR L P + GL +Q+L I G+ Sbjct 76 --ACDVPEELNFLINDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIR 133 Query 1013 YLHAQHYIHRDLAARNVLLDN---DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH IHRDL N++L + + KI D G AK V +G + + + A Sbjct 134 YLHENKIIHRDLKPENIVLQDVGGKIMHKIIDLGYAKDVDQG----SLCTSFVGTLQYLA 189 Query 1070 PECLKEYKFYYASDVWSFGVTLYELL 1095 PE + + D WSFG ++E + Sbjct 190 PELFENKPYTATVDYWSFGTMVFECI 215 >sp|Q9LIG2|RLK6_ARATH Receptor-like protein kinase At3g21340 OS=Arabidopsis thaliana OX=3702 GN=At3g21340 PE=1 SV=1 Length=899 Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 63/204 (31%), Positives = 104/204 (51%), Gaps = 16/204 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LG+G FG V Y T + T E VAVK L ++ +K E+++L ++H++++ Sbjct 596 RVLGKGGFGMV----YHGTVNNT-EQVAVKMLSHSSSQGYKE-FKAEVELLLRVHHKNLV 649 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLHA 1016 G C D+GE +L L+ EY+ G LR+++ G L + +G+ YLH Sbjct 650 GLVGYC-DEGE-NLALIYEYMANGDLREHMSGKRGGSILNWETRLKIVVESAQGLEYLHN 707 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +HRD+ N+LL+ K+ DFGL+++ P E + +P + PE Sbjct 708 GCKPPMVHRDVKTTNILLNEHLHAKLADFGLSRSFPIEGETHVSTVVAGTPGY-LDPEYY 766 Query 1074 KEYKFYYASDVWSFGVTLYELLTH 1097 + SDV+SFG+ L E++T+ Sbjct 767 RTNWLNEKSDVYSFGIVLLEIITN 790 Score = 46.6 bits (109), Expect = 0.002, Method: Compositional matrix adjust. Identities = 64/239 (27%), Positives = 97/239 (41%), Gaps = 35/239 (15%) Query 599 TRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYET 658 T TN +E L G G G +++ + +V +K+L S F Sbjct 589 TMTNNFERVLGKGGFGMVYHGTVNNTE------------QVAVKMLSHSSSQGYKEFKAE 636 Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQ 716 L+ +V H +L + G C G ++ EY+ +G L + +RG + W ++ + Sbjct 637 VELLLRVHHKNLVGLVGYCDEGENLALIYEYMANGDLREHMSGKRGGSILNWETRLKIVV 696 Query 717 QLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREER 772 + A L YL N +VH +V NILL A KL+D G+ + E Sbjct 697 ESAQGLEYLHNGCKPPMVHRDVKTTNILLNEHLHA-------KLADFGLSRSFPIEGETH 749 Query 773 VERIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 V + +L PE N L+ D + FG LLEI + QSR EK H Sbjct 750 VSTVVAGTPGYLDPEYYR--TNWLNEKSDVYSFGIVLLEIITNQLVINQSR---EKPHI 803 >sp|Q69JN6|BRL1_ORYSJ Brassinosteroid LRR receptor kinase BRL1 OS=Oryza sativa subsp. japonica OX=39947 GN=BRL1 PE=2 SV=1 Length=1214 Score = 80.9 bits (198), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 81/301 (27%), Positives = 133/301 (44%), Gaps = 34/301 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG+V G +VA+K L G R + E++ + + H +++ Sbjct 918 IGSGGFGEVY-----KAKLKDGSVVAIKKLIHFTGQGDRE-FTAEMETIGKIKHRNLVPL 971 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-------FAQQICEGMAYLH 1015 G C+ E+ LV EY+ GSL L H A + L A G+A+LH Sbjct 972 LGYCKIGDER--LLVYEYMKHGSLDVVL--HDKAKASVKLDWSARKKIAIGSARGLAFLH 1027 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 H IHRD+ + NVLLDN+ ++ DFG+A+ + + V +P + PE Sbjct 1028 HSCIPHIIHRDMKSSNVLLDNNLDARVSDFGMARLMNALDTHLSVSTLAGTP-GYVPPEY 1086 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLE--LIGIAQGQMTVLRLTELL 1128 + ++ DV+S+GV L ELL S + P PT+F + L+G + + R +E+ Sbjct 1087 YQSFRCTTKGDVYSYGVVLLELL----SGKKPIDPTEFGDNNLVGWVKQMVKENRSSEIF 1142 Query 1129 ERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 + L E+Y +K C + + RPT ++ + K + FS Sbjct 1143 D--PTLTDRKSGEAELYQYLKIACECLDDRPNRRPTMIQVMAMFKELQLDSDSDILDGFS 1200 Query 1186 V 1186 + Sbjct 1201 I 1201 Score = 44.7 bits (104), Expect = 0.007, Method: Compositional matrix adjust. Identities = 55/252 (22%), Positives = 103/252 (41%), Gaps = 36/252 (14%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAW--K 711 F + ++ H +L + G C G E ++V EY++HG LDV L + + V + W + Sbjct 953 FTAEMETIGKIKHRNLVPLLGYCKIGDERLLVYEYMKHGSLDVVLHDKAKASVKLDWSAR 1012 Query 712 MVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGA 766 +A A L++L + +++H ++ N+LL + ++SD G+ + A Sbjct 1013 KKIAIGSARGLAFLHHSCIPHIIHRDMKSSNVLLDN-------NLDARVSDFGMARLMNA 1065 Query 767 LSREERVERIPWLAPECLPGGANSL--STAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 L V + P S +T D + +G LLE+ G+ P+ + Sbjct 1066 LDTHLSVSTLAGTPGYVPPEYYQSFRCTTKGDVYSYGVVLLEL-LSGKKPIDPTEFGDNN 1124 Query 825 HF-----YQRQHRLPEPSCPQLA-------------TLTSQCLTYEPTQRPSFRTILRDL 866 +++R E P L + +CL P +RP+ ++ Sbjct 1125 LVGWVKQMVKENRSSEIFDPTLTDRKSGEAELYQYLKIACECLDDRPNRRPTMIQVMAMF 1184 Query 867 TRLQPHNLADVL 878 LQ + +D+L Sbjct 1185 KELQLDSDSDIL 1196 >sp|Q9SYM9|Y1853_ARATH Receptor-like serine/threonine-protein kinase At1g78530 OS=Arabidopsis thaliana OX=3702 GN=At1g78530 PE=2 SV=1 Length=355 Score = 78.6 bits (192), Expect = 6e-14, Method: Composition-based stats. Identities = 84/290 (29%), Positives = 128/290 (44%), Gaps = 25/290 (9%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 HK K I LG G FG V D D T AVK L + R G+ +E++ + Sbjct 73 HKLSNKDI--LGSGGFGTVYRLVID---DST--TFAVKRLNRGTSERDR-GFHRELEAMA 124 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGM 1011 + H +I+ G L+ E +P GSL +L R ++ A A G+ Sbjct 125 DIKHRNIVTLHGYFTSPHYN--LLIYELMPNGSLDSFLHGRKALDWASRYRIAVGAARGI 182 Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +YLH H IHRD+ + N+LLD++ ++ DFGLA + + G F Y Sbjct 183 SYLHHDCIPHIIHRDIKSSNILLDHNMEARVSDFGLATLMEPDKTHVSTFVAG---TFGY 239 Query 1069 -APECLKEYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKFLELI-GIAQGQMTVL 1122 APE K DV+SFGV L ELLT D TK + + G+ + Q + Sbjct 240 LAPEYFDTGKATMKGDVYSFGVVLLELLTGRKPTDDEFFEEGTKLVTWVKGVVRDQREEV 299 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + L RG + ++ +V+ + C E E + RP ++ +L+ + Sbjct 300 VIDNRL-RGSSVQENEEMN-DVFGIAMMCLEPEPAIRPAMTEVVKLLEYI 347 Score = 45.1 bits (105), Expect = 0.003, Method: Composition-based stats. Identities = 45/183 (25%), Positives = 78/183 (43%), Gaps = 29/183 (16%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F+ M+ + H ++ +HG N+++ E + +G LD +L R + A + Sbjct 115 GFHRELEAMADIKHRNIVTLHGYFTSPHYNLLIYELMPNGSLDSFL-HGRKALDWASRYR 173 Query 714 VAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 +A A +SYL + +++H ++ NILL A ++SD GL L Sbjct 174 IAVGAARGISYLHHDCIPHIIHRDIKSSNILLDHNMEA-------RVSD--FGLATLMEP 224 Query 771 ERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 ++ +LAPE G ++ D + FG LLE+ L R P++ Sbjct 225 DKTHVSTFVAGTFGYLAPEYFDTGKATMKG--DVYSFGVVLLEL-------LTGRKPTDD 275 Query 824 EHF 826 E F Sbjct 276 EFF 278 >sp|Q9SI06|Y5573_ARATH Putative leucine-rich repeat receptor-like serine/threonine-protein kinase At2g04300 OS=Arabidopsis thaliana OX=3702 GN=At2g04300 PE=3 SV=2 Length=892 Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 64/204 (31%), Positives = 106/204 (52%), Gaps = 20/204 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V + ND E VAVK L ++ +K E+++L ++H++++ Sbjct 588 LGKGGFGMV---YHGTVNDA--EQVAVKMLSPSSSQGYKE-FKAEVELLLRVHHKNLVGL 641 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL-----LLFAQQICEGMAYLHAQ 1017 G C D+GE +L L+ EY+ G L++++ + G++ L L + +G+ YLH Sbjct 642 VGYC-DEGE-NLSLIYEYMAKGDLKEHMLGNQ-GVSILDWKTRLKIVAESAQGLEYLHNG 698 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECL 1073 +HRD+ N+LLD K+ DFGL+++ P EG RV + PE Sbjct 699 CKPPMVHRDVKTTNILLDEHFQAKLADFGLSRSFPLEGET--RVDTVVAGTPGYLDPEYY 756 Query 1074 KEYKFYYASDVWSFGVTLYELLTH 1097 + SDV+SFG+ L E++T+ Sbjct 757 RTNWLNEKSDVYSFGIVLLEIITN 780 Score = 54.3 bits (129), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 67/237 (28%), Positives = 97/237 (41%), Gaps = 35/237 (15%) Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660 TN +E L G G G ++D + +V +K+L PS F Sbjct 581 TNNFEKILGKGGFGMVYHGTVNDAE------------QVAVKMLSPSSSQGYKEFKAEVE 628 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK--MVVAQQL 718 L+ +V H +L + G C G ++ EY+ G L + +G + WK + + + Sbjct 629 LLLRVHHKNLVGLVGYCDEGENLSLIYEYMAKGDLKEHMLGNQGVSILDWKTRLKIVAES 688 Query 719 ASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVE 774 A L YL N +VH +V NILL A KL+D G+ L E RV+ Sbjct 689 AQGLEYLHNGCKPPMVHRDVKTTNILLDEHFQA-------KLADFGLSRSFPLEGETRVD 741 Query 775 RIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + +L PE N L+ D + FG LLEI + QSR EK H Sbjct 742 TVVAGTPGYLDPEYYR--TNWLNEKSDVYSFGIVLLEIITNQHVINQSR---EKPHI 793 >sp|Q5XIT0|CDKL2_RAT Cyclin-dependent kinase-like 2 OS=Rattus norvegicus OX=10116 GN=Cdkl2 PE=2 SV=1 Length=507 Score = 79.7 bits (195), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 60/198 (30%), Positives = 101/198 (51%), Gaps = 16/198 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG +G V + C N +G +VA+K L++D + +EI +L+ L HE+++ Sbjct 10 VGEGSYGMV-MKC---RNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65 Query 962 YKGCCEDQGEKSLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 C+ + K LV E+V L L+ + + Q LF QI G+ + H+ + Sbjct 66 LLEVCKKK--KRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLF--QIINGIGFCHSHN 121 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEYK 1077 IHRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L + K Sbjct 122 IIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVK 178 Query 1078 FYYASDVWSFGVTLYELL 1095 + A D+W+ G + E+L Sbjct 179 YGKAVDIWAIGCLVIEML 196 Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 58/238 (24%), Positives = 98/238 (41%), Gaps = 54/238 (23%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ---- 716 L+ Q+ H +L + VC + +V E+V+H LD + P V Q Sbjct 54 LLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILD-----DLKLFPNGLDYQVVQKYLF 108 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVER 775 Q+ + + + + N++H ++ NIL+++ G+ +KL D G A E + Sbjct 109 QIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFARTLAAPGEVYTDY 161 Query 776 IP---WLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGEAP----------LQS 817 + + APE L G A+D W G ++E+ F GE+ L + Sbjct 162 VATRWYRAPELLVGDV-KYGKAVDIWAIGCLVIEMLMGQPLFPGESDIDQLHHIMTCLGN 220 Query 818 RSPSEKEHFYQR----QHRLPE-------------PSCPQLA-TLTSQCLTYEPTQRP 857 P +E FY+ RLPE P P++ +L +CL +P +RP Sbjct 221 LIPRHQELFYKNPVFAGVRLPEIKDIEAEPLESRYPKLPEVVISLAKKCLHIDPDKRP 278 >sp|Q38773|CDC2B_ANTMA Cell division control protein 2 homolog B (Fragment) OS=Antirrhinum majus OX=4151 GN=CDC2B PE=2 SV=1 Length=280 Score = 77.4 bits (189), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 66/212 (31%), Positives = 99/212 (47%), Gaps = 21/212 (10%) Query 915 CYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 Y + T E +A+K ++ + + S +EI +L+ ++HE+I+ K EK Sbjct 5 VYKARDIETNEDIALKKIRLEQEDEGVPSTAIREISLLKEMHHENIVNLKDVV--HREKR 62 Query 974 LQLVMEYVPLGSLR--DYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031 L LV EY+ L + D P S L + +F QI G+AY H+ +HRDL +N+L+ Sbjct 63 LYLVFEYLDLDLKKHMDSCPEFSQDLHMVKMFLCQILRGVAYCHSHRVLHRDLKPQNLLI 122 Query 1032 DN-DRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-APECLKEYKFYYA-SDVWS 1086 D +K+ DFGLA+A +P + V WY APE L + Y DVWS Sbjct 123 DRGSNTIKLADFGLARAFGIPVRTFTHEVV------TLWYRAPEVLLGSRHYSTPVDVWS 176 Query 1087 FGVTLYELLTH-----CDSSQSPPTKFLELIG 1113 G E++ DS K +IG Sbjct 177 VGCIFAEMVNQKPLFPGDSEIDELHKIFRIIG 208 >sp|Q8BGW6|ST32A_MOUSE Serine/threonine-protein kinase 32A OS=Mus musculus OX=10090 GN=Stk32a PE=2 SV=1 Length=398 Score = 79.0 bits (193), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 82/262 (31%), Positives = 125/262 (48%), Gaps = 42/262 (16%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQH--RSGWKQEIDILRTLYH 956 +R +G+G FGKV C ND T +M A+K + K C ++ R+ +K E+ I++ L H Sbjct 26 LRAIGKGSFGKV---CIVRKND-TKKMYAMKYMNKQKCVERNEVRNVFK-ELQIMQGLEH 80 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLH 1015 ++ +D E+ + +V++ + G LR +L ++ + LF ++ + YL Sbjct 81 PFLVNLWYSFQD--EEDMFMVVDLLLGGDLRYHLQQNVHFQEDTVKLFICELAMALDYLQ 138 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-- 1073 +Q IHRD+ N+LLD V I DF +A +P+ V G P + APE Sbjct 139 SQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPKETRITTVA--GTKP--YMAPEMFTS 194 Query 1074 -KEYKFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGI----------AQG 1117 KE + +A D WS GVT YELL H SS S E++ + A Sbjct 195 RKETGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSK----EIVNMFETAIVTYPSAWS 250 Query 1118 QMTVLRLTELLERGERLPRPDK 1139 Q V L +LLE P PD+ Sbjct 251 QEMVSLLKKLLE-----PNPDQ 267 Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust. Identities = 43/171 (25%), Positives = 73/171 (43%), Gaps = 18/171 (11%) Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI 776 +LA AL YL+++ ++H ++ NILL G + ++D + L +E R+ + Sbjct 129 ELAMALDYLQSQRIIHRDMKPDNILLDEHG-------HVHITDFNIA-AMLPKETRITTV 180 Query 777 ----PWLAPECLPGGANS-LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH----FY 827 P++APE + S A+D W G T E+ G P RS + + F Sbjct 181 AGTKPYMAPEMFTSRKETGYSFAVDWWSLGVTAYEL-LRGRRPYHIRSSTSSKEIVNMFE 239 Query 828 QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 P ++ +L + L P QR S T +++ + N VL Sbjct 240 TAIVTYPSAWSQEMVSLLKKLLEPNPDQRFSHLTDIQNFPYMSDMNWDAVL 290 >sp|Q6ZCZ2|BRL3_ORYSJ Brassinosteroid LRR receptor kinase BRL3 OS=Oryza sativa subsp. japonica OX=39947 GN=BRL3 PE=2 SV=1 Length=1214 Score = 80.9 bits (198), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 82/285 (29%), Positives = 131/285 (46%), Gaps = 35/285 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG+V G +VAVK L G R + E++ + + H +++ Sbjct 919 IGSGGFGEVY-----KAKLKDGNIVAVKKLMHFTGQGDRE-FTAEMETIGKIKHRNLVPL 972 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-------FAQQICEGMAYLH 1015 G C+ E+ LV EY+ GSL L H G A + L A G+A+LH Sbjct 973 LGYCKIGDER--LLVYEYMKNGSLDFVL--HDKGEANMDLNWATRKKIAIGSARGLAFLH 1028 Query 1016 ---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 H IHRD+ + NVLLD + + DFG+A+ + + V +P + PE Sbjct 1029 HSCVPHIIHRDMKSSNVLLDGNFDAYVSDFGMARLMNALDSHLTVSMLSGTPG-YVPPEY 1087 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLE--LIGIAQGQMTVLRLTELL 1128 ++++ DV+S+GV L ELLT + P PT+F + L+G + QM R +E+ Sbjct 1088 CQDFRCTTKGDVYSYGVVLLELLT----GKKPIDPTEFGDSNLVGWVK-QMVEDRCSEIY 1142 Query 1129 ERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170 + L E+Y +K C + + + RPT ++ + K Sbjct 1143 D--PTLMATTSSELELYQYLKIACRCLDDQPNRRPTMIQVMTMFK 1185 Score = 35.4 bits (80), Expect = 4.1, Method: Compositional matrix adjust. Identities = 58/263 (22%), Positives = 107/263 (41%), Gaps = 50/263 (19%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM----AW 710 F + ++ H +L + G C G E ++V EY+++G LD L ++G M A Sbjct 954 FTAEMETIGKIKHRNLVPLLGYCKIGDERLLVYEYMKNGSLDFVL-HDKGEANMDLNWAT 1012 Query 711 KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LG 765 + +A A L++L + +++H ++ N+LL +G +SD G+ + Sbjct 1013 RKKIAIGSARGLAFLHHSCVPHIIHRDMKSSNVLL------DGNFD-AYVSDFGMARLMN 1065 Query 766 ALSREERVERIPWLAPECLPGGANSL--STAMDKWGFGATLLEICFDGEAPLQSRSPSE- 822 AL V + P +T D + +G LLE+ G+ P+ P+E Sbjct 1066 ALDSHLTVSMLSGTPGYVPPEYCQDFRCTTKGDVYSYGVVLLEL-LTGKKPID---PTEF 1121 Query 823 ---------KEHFYQRQHRLPEPSCPQLATLTSQ------------CLTYEPTQRPSFRT 861 K+ R + +P+ +AT +S+ CL +P +RP+ Sbjct 1122 GDSNLVGWVKQMVEDRCSEIYDPTL--MATTSSELELYQYLKIACRCLDDQPNRRPTMIQ 1179 Query 862 ILRDLTRLQ---PHNLADVLTVN 881 ++ Q N D ++N Sbjct 1180 VMTMFKEFQVDSGSNFLDDFSLN 1202 >sp|Q9M345|LRK42_ARATH L-type lectin-domain containing receptor kinase IV.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK42 PE=2 SV=1 Length=677 Score = 80.1 bits (196), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 66/200 (33%), Positives = 97/200 (49%), Gaps = 15/200 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG+V Y T VAVK + D Q + EI + + H +++ Sbjct 353 LGSGGFGRV----YRGILPTTKLEVAVKRVSHDS-KQGMKEFVAEIVSIGRMSHRNLVPL 407 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA--- 1016 G C +GE L LV +Y+P GSL YL P ++ Q + + G+ YLH Sbjct 408 LGYCRRRGE--LLLVYDYMPNGSLDKYLYNNPETTLDWKQRSTIIKGVASGLFYLHEEWE 465 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 Q IHRD+ A NVLLD D ++GDFGLA+ G + G + + APE + Sbjct 466 QVVIHRDVKASNVLLDADFNGRLGDFGLARLYDHGSDPQTTHVVG--TLGYLAPEHSRTG 523 Query 1077 KFYYASDVWSFGVTLYELLT 1096 + +DV++FG L E+++ Sbjct 524 RATTTTDVYAFGAFLLEVVS 543 Score = 50.8 bits (120), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 61/235 (26%), Positives = 98/235 (42%), Gaps = 41/235 (17%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM--VVAQQLA 719 + ++SH +L + G C R E ++V +Y+ +G LD +L + WK + + +A Sbjct 396 IGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNNP-ETTLDWKQRSTIIKGVA 454 Query 720 SALSYLE---NKNLVHGNVCGRNILL-----ARLGLAEGTSPFIKLSDPGVGLGALSREE 771 S L YL + ++H +V N+LL RLG + SDP Sbjct 455 SGLFYLHEEWEQVVIHRDVKASNVLLDADFNGRLGDFGLARLYDHGSDP-------QTTH 507 Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-- 829 V + +LAPE G + +T D + FGA LLE+ G P++ S S+ Sbjct 508 VVGTLGYLAPEHSRTGRATTTT--DVYAFGAFLLEVV-SGRRPIEFHSASDDTFLLVEWV 564 Query 830 -----QHRLPEPSCPQLAT-------------LTSQCLTYEPTQRPSFRTILRDL 866 + + E P+L + L C +P RPS R +L+ L Sbjct 565 FSLWLRGNIMEAKDPKLGSSGYDLEEVEMVLKLGLLCSHSDPRARPSMRQVLQYL 619 >sp|O65405|CRK28_ARATH Cysteine-rich receptor-like protein kinase 28 OS=Arabidopsis thaliana OX=3702 GN=CRK28 PE=3 SV=2 Length=683 Score = 80.1 bits (196), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 68/206 (33%), Positives = 100/206 (49%), Gaps = 20/206 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +LG G FG V Y G G+ +AVK L G Q S +K EI +L L H +++ Sbjct 365 NELGRGGFGSV----YKGVFSG-GQEIAVKRLSCTSG-QGDSEFKNEILLLAKLQHRNLV 418 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQ------ICEGMAYL 1014 + G C + E+ L V E++ SL +++ + QLL + + + G+ YL Sbjct 419 RLLGFCIEGQERIL--VYEFIKNASLDNFI--FDLKKRQLLDWGVRYKMIGGVARGLLYL 474 Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWYAP 1070 H IHRDL A N+LLD + KI DFGLAK + +R + AP Sbjct 475 HEDSRYRIIHRDLKASNILLDQEMNPKIADFGLAKLYDTDQTSTHRFTSKIAGTYGYMAP 534 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLT 1096 E +F +DV+SFGV + E++T Sbjct 535 EYAIYGQFSVKTDVFSFGVLVIEIIT 560 Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust. Identities = 53/206 (26%), Positives = 88/206 (43%), Gaps = 29/206 (14%) Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 GQE+ V K L + F L++++ H +L + G C+ G E I+V E++++ Sbjct 383 GQEIAV--KRLSCTSGQGDSEFKNEILLLAKLQHRNLVRLLGFCIEGQERILVYEFIKNA 440 Query 694 PLDVWLRRERGHVPMAW----KMVVAQQLASALSYLENKN---LVHGNVCGRNILL---- 742 LD ++ + + W KM+ +A L YL + ++H ++ NILL Sbjct 441 SLDNFIFDLKKRQLLDWGVRYKMIGG--VARGLLYLHEDSRYRIIHRDLKASNILLDQEM 498 Query 743 ----ARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKW 798 A GLA KL D + ++APE G S+ T D + Sbjct 499 NPKIADFGLA-------KLYDTDQTSTHRFTSKIAGTYGYMAPEYAIYGQFSVKT--DVF 549 Query 799 GFGATLLEICFDGEAPLQSRSPSEKE 824 FG ++EI G+ RS ++E Sbjct 550 SFGVLVIEI-ITGKGNNNGRSNDDEE 574 >sp|Q54XX5|Y9849_DICDI Probable serine/threonine-protein kinase DDB_G0278535 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0278535 PE=3 SV=1 Length=848 Score = 80.5 bits (197), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 78/288 (27%), Positives = 122/288 (42%), Gaps = 26/288 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G GKV Y G+ VAVK LK+ +K+E I+ ++ + ++ + Sbjct 535 LGSGSSGKVYKGLYK------GKEVAVKVLKSITTQSQLEEFKKEFQIMGSIRSQFMVTF 588 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLH--AQH 1018 G C E L +VMEY SL + ++ IG + F Q+ G+ LH Sbjct 589 YGAC---IEPKLCMVMEYCSRDSLYHVMNTKKYDIGWDRFFQFTMQMTLGVQCLHNWTPQ 645 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKEYK 1077 +HRD + N+L++ D K+ DFGL++ + + G F Y +PE Sbjct 646 IVHRDFKSLNLLVNEDWECKVSDFGLSRFNTADNLETLSKIRG---TFAYCSPEVAVGNG 702 Query 1078 FYYA--SDVWSFGVTLYELLTHC-DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 Y SD++S G+ +EL+T + S P + E I +L E G R Sbjct 703 SLYTTKSDIYSIGIVFWELVTRVINGEYSRP--YSEYSHIKMDFQIMLNSKE----GLRP 756 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182 P P + L K C E + RP+ E +I L + +Y + Sbjct 757 TLPQNTPPGLEALYKQCVNQEQTLRPSCEEIIETLNRLRHEYMSSKTT 804 Score = 41.2 bits (95), Expect = 0.080, Method: Compositional matrix adjust. Identities = 70/317 (22%), Positives = 112/317 (35%), Gaps = 59/317 (19%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L+ L +D E+ LG G+ VY+G L G++ Sbjct 516 LTNLEHWVIDHSELEYTLKLGSGSSGKVYKG--------------------LYKGKE--- 552 Query 636 ELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 V +KVL L F + +M + + +G C+ P+ MV EY Sbjct 553 ---VAVKVLKSITTQSQLEEFKKEFQIMGSIRSQFMVTFYGACIE-PKLCMVMEYCSRDS 608 Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGLAEGTS 752 L + ++ + Q+ + L N +VH + N+L+ Sbjct 609 LYHVMNTKKYDIGWDRFFQFTMQMTLGVQCLHNWTPQIVHRDFKSLNLLV-------NED 661 Query 753 PFIKLSDPGVG-LGALSREERVERI----PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 K+SD G+ E + +I + +PE G + +T D + G E+ Sbjct 662 WECKVSDFGLSRFNTADNLETLSKIRGTFAYCSPEVAVGNGSLYTTKSDIYSIGIVFWEL 721 Query 808 C---FDGEAPLQSRSPSEKEHFYQR-----------QHRLPEPSCPQLATLTSQCLTYEP 853 +GE SR SE H + LP+ + P L L QC+ E Sbjct 722 VTRVINGEY---SRPYSEYSHIKMDFQIMLNSKEGLRPTLPQNTPPGLEALYKQCVNQEQ 778 Query 854 TQRPSFRTILRDLTRLQ 870 T RPS I+ L RL+ Sbjct 779 TLRPSCEEIIETLNRLR 795 >sp|Q9TZM3|LRK1_CAEEL Leucine-rich repeat serine/threonine-protein kinase 1 OS=Caenorhabditis elegans OX=6239 GN=lrk-1 PE=1 SV=6 Length=2393 Score = 80.9 bits (198), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 98/338 (29%), Positives = 141/338 (42%), Gaps = 82/338 (24%) Query 882 PDSPASD---PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM--VAVKALK-AD 935 PD+ +D H LK+ R LG G FG V N GE+ VA K L+ D Sbjct 1676 PDTVFADIENALTIHPDQLKRSRMLGRGAFGFVFRATVRQPN---GELCEVAQKMLEPVD 1732 Query 936 CGPQHR-----------SGWK---------------QEIDILRTLYHEHIIKYKGCCEDQ 969 GP R WK QE+ +L + H ++I G C Sbjct 1733 PGPGGRPSALAAYKAAADKWKRDSMEFACRAYCTSRQELSLLSRMKHPNVIGLVGVCT-- 1790 Query 970 GEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHAQHYIHRDL 1024 L LV+E PLG+L L H + L + A Q+ + YLH+ H I+RDL Sbjct 1791 --FPLSLVVELAPLGALNQLLGSHRKAGTKLSLGVIKESAVQVARALEYLHSAHIIYRDL 1848 Query 1025 AARNVL---------LDNDRLVKIGDFGLAKAV-PEGHEYYRVREDGDSPVFWYAPECLK 1074 + NVL D L+K+GD+G++++V P G +G + APE ++ Sbjct 1849 KSENVLGWRFPAPFSPQTDVLLKLGDYGISRSVLPSGGAKGFGGTEG-----FMAPEIVR 1903 Query 1075 ---EYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 E ++ D +SFG+ LYELLT +S + + L+ G VL ELL Sbjct 1904 FNGEEEYTQKVDCFSFGMFLYELLTLKFPFESEEHVKERMLD------GARPVLLPHELL 1957 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 LP P + L+ +CW RP+ L+ Sbjct 1958 -----LPTP------MLDLLVHCWSAHPESRPSSSQLV 1984 >sp|Q8VBY2|KKCC1_MOUSE Calcium/calmodulin-dependent protein kinase kinase 1 OS=Mus musculus OX=10090 GN=Camkk1 PE=1 SV=1 Length=505 Score = 79.7 bits (195), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 51/150 (34%), Positives = 79/150 (53%), Gaps = 6/150 (4%) Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ 1005 QEI IL+ L H +++K +D E +L LV + + G + + Q L+ + Sbjct 198 QEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFPEEQARLYLR 257 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 I G+ YLH Q +HRD+ N+LL +D VKI DFG++ EG++ ++ +P Sbjct 258 DIILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF-EGND-AQLSSTAGTPA 315 Query 1066 FWYAPECLKEYKFYY---ASDVWSFGVTLY 1092 F APE + + + A DVW+ GVTLY Sbjct 316 FM-APEAISDSGQSFSGKALDVWATGVTLY 344 >sp|P52389|CDC2_VIGUN Cell division control protein 2 homolog OS=Vigna unguiculata OX=3917 GN=CDC2 PE=2 SV=1 Length=294 Score = 77.4 bits (189), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 64/207 (31%), Positives = 101/207 (49%), Gaps = 20/207 (10%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYH 956 +K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ + H Sbjct 5 EKVEKIGEGTYGVV----YKARDRVTDETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR--DYLPRHSIGLAQLLLFAQQICEGMAYL 1014 +I++ + EK L LV EY+ L + D P Q+ +F QI G+AY Sbjct 61 RNIVRLQDVV--HSEKRLYLVFEYLDLDLKKHMDSSPEFVKDPRQVKMFLYQILCGIAYC 118 Query 1015 HAQHYIHRDLAARNVLLD-NDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070 H+ +HRDL +N+L+D +K+ DFGLA+A +P + V WY AP Sbjct 119 HSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEV------VTLWYRAP 172 Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLT 1096 E L + Y DVWS G E++ Sbjct 173 EILLGSRHYSTPVDVWSVGCLFAEMVN 199 >sp|Q6EU49|WNK4_ORYSJ Probable serine/threonine-protein kinase WNK4 OS=Oryza sativa subsp. japonica OX=39947 GN=WNK4 PE=2 SV=1 Length=612 Score = 80.1 bits (196), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 65/216 (30%), Positives = 105/216 (49%), Gaps = 20/216 (9%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD---CGPQHRSGW 944 DPT +RY++ LG G V Y ++ G VA ++ D P + Sbjct 19 DPT---RRYIRYNEVLGRGAMKTV----YKAFDEVEGIEVAWSQVEIDEVMQSPDNLERL 71 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLF 1003 E+ +L++L HE+++K+ D +K++ ++ E GSLR Y +H + L + + Sbjct 72 YSEVHLLKSLKHENVMKFYNYWVDDQKKTINVITELFTSGSLRQYRQKHPRVDLKAIKNW 131 Query 1004 AQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 A+Q+ G+ YLH IHRDL N+ ++ N VKIGD GLA + R + Sbjct 132 ARQVLRGLDYLHTHQPPIIHRDLKCDNIFVNGNHGEVKIGDLGLATVMLTP----RAKSV 187 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 +P F APE E + D++SFG+ + E+ T Sbjct 188 IGTPEFM-APELYDE-NYDELVDIYSFGMCMLEMFT 221 >sp|Q9DGA2|CDK1_ORYJA Cyclin-dependent kinase 1 OS=Oryzias javanicus OX=123683 GN=cdk1 PE=2 SV=1 Length=303 Score = 77.4 bits (189), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 66/215 (31%), Positives = 109/215 (51%), Gaps = 25/215 (12%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957 KI +GEG +G V Y + TG++VA+K ++ + + S +E+ +L+ L H Sbjct 6 KIEKIGEGTYGVV----YKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLL--FAQQICEGMAY 1013 ++++ E L L+ E++ + L+ YL G + +L+ + QI EG+ + Sbjct 62 NVVRLLDVL--MQESRLYLIFEFLSM-DLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWYAPE 1071 H + +HRDL +N+L+DN ++K+ DFGLA+A VP RV +++ APE Sbjct 119 CHRRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVP-----VRVYTHEVVTLWYRAPE 173 Query 1072 C-LKEYKFYYASDVWSFGVTLYELLT-----HCDS 1100 L ++ DVWS G EL T H DS Sbjct 174 VLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDS 208 >sp|O49717|CDPKF_ARATH Calcium-dependent protein kinase 15 OS=Arabidopsis thaliana OX=3702 GN=CPK15 PE=2 SV=1 Length=554 Score = 79.7 bits (195), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 83/296 (28%), Positives = 132/296 (45%), Gaps = 34/296 (11%) Query 815 LQSRSPSEK-EHFYQRQHRLPE-PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 +QS P+ + E+ R P+ P PQ+ T T ++ +P + I + QP Sbjct 20 VQSSIPTNQPENHVSRDVLKPQKPPSPQIPTTTQSNHHHQQESKPVNQQIEKKHVLTQP- 78 Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932 L ++ ++ P ++ ++LG G FG Y + TG A K++ Sbjct 79 -LKPIVFRETETILGKPFEEIRKLYTLGKELGRGQFG----ITYTCKENSTGNTYACKSI 133 Query 933 --KADCGPQHRSGWKQEIDILRTLY-HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD- 988 + Q K+EI I++ L E+I++ KG ED+ +S+ LVME L D Sbjct 134 LKRKLTRKQDIDDVKREIQIMQYLSGQENIVEIKGAYEDR--QSIHLVMELCGGSELFDR 191 Query 989 ------YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKI 1039 Y + + G+ + +L QIC H IHRDL N LL D + ++K Sbjct 192 IIAQGHYSEKAAAGVIRSVLNVVQIC------HFMGVIHRDLKPENFLLASTDENAMLKA 245 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 DFGL+ + EG +V D ++ APE L+ + D+WS G+ LY LL Sbjct 246 TDFGLSVFIEEG----KVYRDIVGSAYYVAPEVLRR-SYGKEIDIWSAGIILYILL 296 >sp|Q8GUQ5|BRI1_SOLLC Brassinosteroid LRR receptor kinase OS=Solanum lycopersicum OX=4081 GN=CURL3 PE=1 SV=1 Length=1207 Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 76/251 (30%), Positives = 118/251 (47%), Gaps = 26/251 (10%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 FH L +G G FG V G +VA+K L G R + E++ + Sbjct 888 FHNDSL-----VGSGGFGDVY-----KAQLKDGSVVAIKKLIHVSGQGDRE-FTAEMETI 936 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQIC-- 1008 + H +++ G C+ GE+ L LV EY+ GSL D L R IG+ ++I Sbjct 937 GKIKHRNLVPLLGYCK-VGEERL-LVYEYMKYGSLEDVLHDRKKIGIKLNWPARRKIAIG 994 Query 1009 --EGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 G+A+LH H IHRD+ + NVLLD + ++ DFG+A+ + + V + Sbjct 995 AARGLAFLHHNCIPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGT 1054 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI----AQGQM 1119 P + PE + ++ DV+S+GV L ELLT + S L+G A+G++ Sbjct 1055 PG-YVPPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFGDNNLVGWVKLHAKGKI 1113 Query 1120 TVLRLTELLER 1130 T + ELL+ Sbjct 1114 TDVFDRELLKE 1124 Score = 36.6 bits (83), Expect = 2.0, Method: Compositional matrix adjust. Identities = 24/94 (26%), Positives = 49/94 (52%), Gaps = 6/94 (6%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAW--K 711 F + ++ H +L + G C G E ++V EY+++G L DV R++ + + W + Sbjct 929 FTAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKYGSLEDVLHDRKKIGIKLNWPAR 988 Query 712 MVVAQQLASALSYLENK---NLVHGNVCGRNILL 742 +A A L++L + +++H ++ N+LL Sbjct 989 RKIAIGAARGLAFLHHNCIPHIIHRDMKSSNVLL 1022 >sp|Q02723|RKIN1_SECCE Carbon catabolite-derepressing protein kinase OS=Secale cereale OX=4550 GN=RKIN1 PE=2 SV=1 Length=502 Score = 79.7 bits (195), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 73/208 (35%), Positives = 97/208 (47%), Gaps = 21/208 (10%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILR- 952 YL KI LG G F KV + + T VA+K L + P+ K+EI ILR Sbjct 15 YLGKI--LGVGTFAKVII----AEHKHTRHKVAIKVLNRRQMRAPEMEEKAKREIKILRL 68 Query 953 --TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICE 1009 L H HII+ K + +VMEY G L DY L + + + QQI Sbjct 69 FIDLIHPHIIRVYEVI--VTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQIIS 126 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + Y H +HRDL N+LLD+ VK+ DFGL+ + +GH + + + A Sbjct 127 AVEYCHRNKVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGH----FLKTSCGSLNYAA 182 Query 1070 PECLKEYKFYYAS--DVWSFGVTLYELL 1095 PE + K Y DVWS GV LY LL Sbjct 183 PEVISG-KLYAGPEIDVWSCGVILYALL 209 Score = 38.9 bits (89), Expect = 0.32, Method: Compositional matrix adjust. Identities = 55/238 (23%), Positives = 96/238 (40%), Gaps = 26/238 (11%) Query 638 RVVLKVLD------PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +V +KVL+ P + A + L + H H+ V+ V V + +V EY + Sbjct 39 KVAIKVLNRRQMRAPEMEEKAKREIKILRLFIDLIHPHIIRVYEVIVTPKDIFVVMEYCQ 98 Query 692 HGPL-DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 +G L D L + R A + QQ+ SA+ Y +VH ++ N+LL Sbjct 99 NGDLLDYILEKRRLQEDEARRTF--QQIISAVEYCHRNKVVHRDLKPENLLL-------D 149 Query 751 TSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + +KL+D GL + + + + + APE + G + +D W G L Sbjct 150 SKYNVKLAD--FGLSNVMHDGHFLKTSCGSLNYAAPEVISGKLYA-GPEIDVWSCGVILY 206 Query 806 EICFDGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 + G P + P+ + + LP + L S+ L +P +R + I Sbjct 207 AL-LCGAVPFDDDNIPNLFKKIKGGTYILPIYLSDLVRDLISRMLIVDPMKRITIGEI 263 >sp|Q7Z8E9|STE20_PYRO7 Serine/threonine-protein kinase MST20 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507 GN=MST20 PE=3 SV=3 Length=914 Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 53/208 (25%), Positives = 100/208 (48%), Gaps = 14/208 (7%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DP ++ + K +G+G G V Y G+ +VA+K + + P+ + E Sbjct 629 DPREIYRSFTK----IGQGASGGV----YTGHERGSNRLVAIKQMNLEQQPK-KDLIINE 679 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +++ H +I+ + GE L +VME++ GSL D + + + Q+ ++ Sbjct 680 ILVMKDSSHPNIVNFIDSYLCGGE--LWVVMEFMEGGSLTDVVTFNIMTEGQIASVCRET 737 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 G+ +LH++ IHRD+ + N+LL + +K+ DFG + +E R +W Sbjct 738 LLGLQHLHSKGVIHRDIKSDNILLSMEGNIKLTDFGFCATI---NEAQNKRTTMVGTPYW 794 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095 APE + ++ D+WS G+ E++ Sbjct 795 MAPEVVTRKEYGRKVDIWSLGIMAIEMI 822 Score = 41.6 bits (96), Expect = 0.057, Method: Compositional matrix adjust. Identities = 50/205 (24%), Positives = 83/205 (40%), Gaps = 36/205 (18%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G +RG V +K ++ +M SH ++ + G E +V E+ Sbjct 651 GHERGSNRLVAIKQMNLEQQPKKDLIINEILVMKDSSHPNIVNFIDSYLCGGELWVVMEF 710 Query 690 VEHGPL-DVWLRRERGHVPMAWKMVVAQQLAS-------ALSYLENKNLVHGNVCGRNIL 741 +E G L DV + + ++ Q+AS L +L +K ++H ++ NIL Sbjct 711 MEGGSLTDV----------VTFNIMTEGQIASVCRETLLGLQHLHSKGVIHRDIKSDNIL 760 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP------WLAPECLPGGANSLSTAM 795 L+ G IKL+D G A E + +R W+APE + + Sbjct 761 LSMEG-------NIKLTD--FGFCATINEAQNKRTTMVGTPYWMAPEVV--TRKEYGRKV 809 Query 796 DKWGFGATLLEICFDGEAPLQSRSP 820 D W G +E+ +GE P + SP Sbjct 810 DIWSLGIMAIEM-IEGEPPYLTESP 833 >sp|Q9LX29|ACR4L_ARATH Serine/threonine-protein kinase-like protein ACR4 OS=Arabidopsis thaliana OX=3702 GN=ACR4 PE=1 SV=1 Length=895 Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 75/250 (30%), Positives = 114/250 (46%), Gaps = 41/250 (16%) Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 DL LQ A V T A+D K+ +G+G F S DGT Sbjct 487 DLDELQKRRRARVFTYEELEKAADG-------FKEESIVGKGSF---SCVYKGVLRDGT- 535 Query 925 EMVAVK-ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 VAVK A+ + ++ + ++ E+D+L L H H++ G CE+ GE+ LV E++ Sbjct 536 -TVAVKRAIMSSDKQKNSNEFRTELDLLSRLNHAHLLSLLGYCEECGER--LLVYEFMAH 592 Query 984 GSLRDYLPRHSIGLAQLL------LFAQQICEGMAYLHAQH---YIHRDLAARNVLLDND 1034 GSL ++L + L + L A Q G+ YLH IHRD+ + N+L+D + Sbjct 593 GSLHNHLHGKNKALKEQLDWVKRVTIAVQAARGIEYLHGYACPPVIHRDIKSSNILIDEE 652 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF--------WYAPECLKEYKFYYASDVWS 1086 ++ DFGL+ P D SP+ + PE + + SDV+S Sbjct 653 HNARVADFGLSLLGP---------VDSGSPLAELPAGTLGYLDPEYYRLHYLTTKSDVYS 703 Query 1087 FGVTLYELLT 1096 FGV L E+L+ Sbjct 704 FGVLLLEILS 713 Score = 43.5 bits (101), Expect = 0.013, Method: Compositional matrix adjust. Identities = 53/222 (24%), Positives = 90/222 (41%), Gaps = 33/222 (15%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 S +G+G+ + VY+G LR G + V ++ + Sbjct 516 SIVGKGSFSCVYKGVLR-----------------------DGTTVAVKRAIMSSDKQKNS 552 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP--MAW 710 F L+S+++H HL + G C E ++V E++ HG L L + + + W Sbjct 553 NEFRTELDLLSRLNHAHLLSLLGYCEECGERLLVYEFMAHGSLHNHLHGKNKALKEQLDW 612 Query 711 --KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 ++ +A Q A + YL ++H ++ NIL+ A + L P V G Sbjct 613 VKRVTIAVQAARGIEYLHGYACPPVIHRDIKSSNILIDEEHNARVADFGLSLLGP-VDSG 671 Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 + E + +L PE + L+T D + FG LLEI Sbjct 672 SPLAELPAGTLGYLDPEYYR--LHYLTTKSDVYSFGVLLLEI 711 >sp|P97756|KKCC1_RAT Calcium/calmodulin-dependent protein kinase kinase 1 OS=Rattus norvegicus OX=10116 GN=Camkk1 PE=1 SV=1 Length=505 Score = 79.7 bits (195), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 51/150 (34%), Positives = 79/150 (53%), Gaps = 6/150 (4%) Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ 1005 QEI IL+ L H +++K +D E +L LV + + G + + Q L+ + Sbjct 198 QEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFPEEQARLYLR 257 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 I G+ YLH Q +HRD+ N+LL +D VKI DFG++ EG++ ++ +P Sbjct 258 DIILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF-EGND-AQLSSTAGTPA 315 Query 1066 FWYAPECLKEYKFYY---ASDVWSFGVTLY 1092 F APE + + + A DVW+ GVTLY Sbjct 316 FM-APEAISDTGQSFSGKALDVWATGVTLY 344 >sp|O64784|Y1136_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61360 OS=Arabidopsis thaliana OX=3702 GN=At1g61360 PE=2 SV=1 Length=821 Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 65/204 (32%), Positives = 96/204 (47%), Gaps = 16/204 (8%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LG+G FG V G+ +AVK L + Q + EI ++ L H ++ Sbjct 501 LNKLGQGGFGTVY-----KGKLQDGKEIAVKRLTSS-SVQGTEEFMNEIKLISKLQHRNL 554 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLR----DYLPRHSIGLAQLLLFAQQICEGMAYLH 1015 ++ GCC D GE+ L LV EY+ SL D + I A Q I G+ YLH Sbjct 555 LRLLGCCID-GEEKL-LVYEYMVNKSLDIFIFDLKKKLEIDWATRFNIIQGIARGLLYLH 612 Query 1016 AQHY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 + +HRDL N+LLD KI DFGLA+ G+++ + + +PE Sbjct 613 RDSFLRVVHRDLKVSNILLDEKMNPKISDFGLARLF-HGNQHQDSTGSVVGTLGYMSPEY 671 Query 1073 LKEYKFYYASDVWSFGVTLYELLT 1096 F SD++SFGV + E++T Sbjct 672 AWTGTFSEKSDIYSFGVLMLEIIT 695 Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 59/244 (24%), Positives = 105/244 (43%), Gaps = 43/244 (18%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 LN ++ + + L+ LGQG VY+G+L ++GK Sbjct 483 LNFFEIHDLQTATNNFSVLNKLGQGGFGTVYKGKL--------QDGK------------- 521 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + +K L S F L+S++ H +L + G C+ G E ++V EY+ + Sbjct 522 ----EIAVKRLTSSSVQGTEEFMNEIKLISKLQHRNLLRLLGCCIDGEEKLLVYEYMVNK 577 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 LD+++ + + + W + + Q +A L YL + + V R++ ++ + L E Sbjct 578 SLDIFIFDLKKKLEIDWATRFNIIQGIARGLLYLHRDSFLR--VVHRDLKVSNILLDEKM 635 Query 752 SPFIKLSDPGVGLGAL--------SREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +P K+SD GL L S V + +++PE G + S D + FG Sbjct 636 NP--KISD--FGLARLFHGNQHQDSTGSVVGTLGYMSPEYAWTG--TFSEKSDIYSFGVL 689 Query 804 LLEI 807 +LEI Sbjct 690 MLEI 693 >sp|Q9LJF3|BRL3_ARATH Receptor-like protein kinase BRI1-like 3 OS=Arabidopsis thaliana OX=3702 GN=BRL3 PE=1 SV=1 Length=1164 Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 82/285 (29%), Positives = 126/285 (44%), Gaps = 32/285 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V G +VA+K L G R + E++ + + H +++ Sbjct 864 IGSGGFGDVY-----KAKLADGSVVAIKKLIQVTGQGDRE-FMAEMETIGKIKHRNLVPL 917 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL------LFAQQICEGMAYLHA 1016 G C+ GE+ L LV EY+ GSL L + L A G+A+LH Sbjct 918 LGYCK-IGEERL-LVYEYMKYGSLETVLHEKTKKGGIFLDWSARKKIAIGAARGLAFLHH 975 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 H IHRD+ + NVLLD D + ++ DFG+A+ V + V +P + PE Sbjct 976 SCIPHIIHRDMKSSNVLLDQDFVARVSDFGMARLVSALDTHLSVSTLAGTP-GYVPPEYY 1034 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLE---LIGIAQGQMTVLRLTELL 1128 + ++ DV+S+GV L ELL S + P P +F E L+G A+ R E+L Sbjct 1035 QSFRCTAKGDVYSYGVILLELL----SGKKPIDPEEFGEDNNLVGWAKQLYREKRGAEIL 1090 Query 1129 ERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170 + L E+ H +K C + RPT ++ + K Sbjct 1091 D--PELVTDKSGDVELLHYLKIASQCLDDRPFKRPTMIQVMTMFK 1133 Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust. Identities = 58/260 (22%), Positives = 110/260 (42%), Gaps = 57/260 (22%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL--RRERGHVPMAW-- 710 F + ++ H +L + G C G E ++V EY+++G L+ L + ++G + + W Sbjct 899 FMAEMETIGKIKHRNLVPLLGYCKIGEERLLVYEYMKYGSLETVLHEKTKKGGIFLDWSA 958 Query 711 KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LG 765 + +A A L++L + +++H ++ N+LL + +A ++SD G+ + Sbjct 959 RKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDQDFVA-------RVSDFGMARLVS 1011 Query 766 ALSREERVERIP----WLAPE------CLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 AL V + ++ PE C G D + +G LLE+ G+ P+ Sbjct 1012 ALDTHLSVSTLAGTPGYVPPEYYQSFRCTAKG--------DVYSYGVILLEL-LSGKKPI 1062 Query 816 QSRSPSEKEHFY------QRQHRLPEPSCPQLAT-------------LTSQCLTYEPTQR 856 E + R+ R E P+L T + SQCL P +R Sbjct 1063 DPEEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELLHYLKIASQCLDDRPFKR 1122 Query 857 PSF---RTILRDLTRLQPHN 873 P+ T+ ++L ++ N Sbjct 1123 PTMIQVMTMFKELVQVDTEN 1142 >sp|F4ICB6|IBS1_ARATH Protein IMPAIRED IN BABA-INDUCED STERILITY 1 OS=Arabidopsis thaliana OX=3702 GN=IBS1 PE=3 SV=1 Length=709 Score = 80.1 bits (196), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 63/209 (30%), Positives = 98/209 (47%), Gaps = 12/209 (6%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDI 950 F +K+ +G+G + V + TG +VA+K ++ D P+ +EI I Sbjct 126 FRSDAFEKLEKIGQGTYSSV----FRARETETGRIVALKKVRFDNFEPESVRFMAREILI 181 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQIC 1008 LR L H +IIK +G + S+ LV EY+ L L I Q+ + +Q+ Sbjct 182 LRKLNHPNIIKLEGIVTSKLSCSIHLVFEYME-HDLTGLLSSPDIDFTTPQIKCYMKQLL 240 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 G+ + HA+ +HRD+ N+L++N+ ++K+ DFGLA + WY Sbjct 241 SGLDHCHARGVMHRDIKGSNLLVNNEGILKVADFGLANFCNASGNKQPL--TSRVVTLWY 298 Query 1069 A-PECLKEYKFYYAS-DVWSFGVTLYELL 1095 PE L Y AS D+WS G ELL Sbjct 299 RPPELLLGATEYGASVDLWSVGCVFAELL 327 >sp|P87253|KPC1_NEUCR Protein kinase C-like OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=NCU06544 PE=3 SV=2 Length=1142 Score = 80.5 bits (197), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 59/198 (30%), Positives = 90/198 (45%), Gaps = 14/198 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-----GWKQEIDILRTLYHE 957 LG+G+FGKV L + ++ A+K LK + ++ K+ I H Sbjct 823 LGKGNFGKVML----AETKKSRKLYAIKVLKKEFIIENDEVESIRSEKRVFLIANRERHP 878 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + C Q E + VMEY+ G L ++ R G + +A ++C + Y H Sbjct 879 FLTNLHACF--QTETRVYFVMEYISGGDLMLHIQRGMFGTKRAQFYAAEVCLALKYFHEN 936 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 I+RDL N+LL D +KI D+GL K E Y + APE L + K Sbjct 937 GVIYRDLKLDNILLTLDGHIKIADYGLCK---EDMWYGSTTSTFCGTPEFMAPEILLDKK 993 Query 1078 FYYASDVWSFGVTLYELL 1095 + A D W+FGV +Y++L Sbjct 994 YGRAVDWWAFGVLIYQML 1011 >sp|Q8SQW2|CTK1_ENCCU Probable CTD kinase subunit alpha homolog OS=Encephalitozoon cuniculi (strain GB-M1) OX=284813 GN=CTK1 PE=3 SV=1 Length=329 Score = 77.8 bits (190), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 67/245 (27%), Positives = 111/245 (45%), Gaps = 22/245 (9%) Query 885 PASDPTVF-HKRY------LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 PA + + H+R+ +KIR +GEG FG+V L G K K G Sbjct 3 PAEEGEILAHRRFTATKMEYEKIRIIGEGTFGQVIL-----ARKGRARYALKKVSKEKEG 57 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL 997 + +E+ +LR + H I++ + G + +V Y P L ++ + + Sbjct 58 LSVTT--IREVQVLRAMGHPSIVRLIEVVVEPG-GDIYMVFPYFPY-DLNRFIRSNKMTC 113 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 +++ QI +G+ Y+H++ +HRDL + N+LLD I DFG+A+ + Y Sbjct 114 SEIKHIFYQIAQGVCYIHSKGIMHRDLKSANILLDQKLNASIADFGMARYTTKTGAY--- 170 Query 1058 REDGDSPVFWYAPEC-LKEYKFYYASDVWSFGVTLYEL-LTHCDSSQSPPTKFLELIGIA 1115 G +++ APE L + YA D+WS G L E+ L H S LE++ A Sbjct 171 -TPGMVTLWYRAPEILLGSSSYTYAVDIWSLGCILTEMYLGHMIFQGSTEMLQLEMVIHA 229 Query 1116 QGQMT 1120 G + Sbjct 230 CGSIN 234 >sp|P10666|KS6AB_XENLA Ribosomal protein S6 kinase 2 beta OS=Xenopus laevis OX=8355 PE=2 SV=1 Length=629 Score = 79.7 bits (195), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 57/199 (29%), Positives = 104/199 (52%), Gaps = 8/199 (4%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEH 958 ++ LG+G FGKV L T ++ A+K LK A + R K E DIL ++H Sbjct 65 LKVLGQGSFGKVFL-VRKITPPDANQLYAMKVLKKATLKVRDRVRTKMERDILADVHHPF 123 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ-LLLFAQQICEGMAYLHAQ 1017 +++ + +G+ L L+++++ G L L + + + + + ++ G+ +LH+ Sbjct 124 VVRLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSL 181 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 I+RDL N+LLD + +K+ DFGL+K E ++ + V + APE + Sbjct 182 GIIYRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKKAYSFCGTVEYMAPEVVNRQG 238 Query 1078 FYYASDVWSFGVTLYELLT 1096 + +D WS+GV ++E+LT Sbjct 239 HSHGADWWSYGVLMFEMLT 257 Score = 61.2 bits (147), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 59/194 (30%), Positives = 91/194 (47%), Gaps = 30/194 (15%) Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKS 973 C + GT AVK + + + +EI+ILR H +II K E+ S Sbjct 430 CKRCVHKGTNMEYAVKVID-----KSKRDPSEEIEILRRYGQHPNIITLKDVYEECN--S 482 Query 974 LQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030 + LV E + G L D + R S A +LF +C+ + YLH+Q +HRDL N+L Sbjct 483 IYLVTELMRGGELLDRILRQKFFSEREACSVLFT--VCKTVEYLHSQGVVHRDLKPSNIL 540 Query 1031 LDND----RLVKIGDFGLAKAVPEGHEYYRVREDG--DSPVF---WYAPECLKEYKFYYA 1081 ++ ++I DFG +K + E+G +P + + APE LK + Sbjct 541 YVDESGDPESIRICDFGFSKQLRA--------ENGLLMTPCYTANFVAPEVLKRQGYDEG 592 Query 1082 SDVWSFGVTLYELL 1095 D+WS G+ LY +L Sbjct 593 CDIWSLGILLYTML 606 >sp|O81069|Y2899_ARATH Probable leucine-rich repeat receptor-like protein kinase At2g28990 OS=Arabidopsis thaliana OX=3702 GN=At2g28990 PE=1 SV=1 Length=884 Score = 80.1 bits (196), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 62/204 (30%), Positives = 98/204 (48%), Gaps = 16/204 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 + LGEG FG V + E VAVK L + Q +K E+++L ++H +++ Sbjct 581 KALGEGGFGVVYHGFVNVI-----EQVAVKLL-SQSSSQGYKHFKAEVELLMRVHHINLV 634 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA----QLLLFAQQICEGMAYLHA 1016 G C D+GE L L+ EY+P G L+ +L G L G+ YLH Sbjct 635 SLVGYC-DEGEH-LALIYEYMPNGDLKQHLSGKHGGFVLSWESRLKIVLDAALGLEYLHT 692 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +HRD+ N+LLD K+ DFGL+++ P G+E +P + PE Sbjct 693 GCVPPMVHRDIKTTNILLDQHLQAKLADFGLSRSFPIGNEKNVSTVVAGTPGYL-DPEYY 751 Query 1074 KEYKFYYASDVWSFGVTLYELLTH 1097 + SD++SFG+ L E++++ Sbjct 752 QTNWLTEKSDIYSFGIVLLEIISN 775 Score = 45.8 bits (107), Expect = 0.003, Method: Compositional matrix adjust. Identities = 54/202 (27%), Positives = 85/202 (42%), Gaps = 23/202 (11%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K+L S F L+ +V H +L + G C G ++ EY+ +G L Sbjct 601 QVAVKLLSQSSSQGYKHFKAEVELLMRVHHINLVSLVGYCDEGEHLALIYEYMPNGDLKQ 660 Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752 L + G ++W ++ + A L YL +VH ++ NILL + A Sbjct 661 HLSGKHGGFVLSWESRLKIVLDAALGLEYLHTGCVPPMVHRDIKTTNILLDQHLQA---- 716 Query 753 PFIKLSDPGVGLG-ALSREERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATLLE 806 KL+D G+ + E+ V + +L PE N L+ D + FG LLE Sbjct 717 ---KLADFGLSRSFPIGNEKNVSTVVAGTPGYLDPEYYQ--TNWLTEKSDIYSFGIVLLE 771 Query 807 ICFDGEAPLQSRSPSEKEHFYQ 828 I + QSR EK H + Sbjct 772 IISNRPIIQQSR---EKPHIVE 790 >sp|Q2NL51|GSK3A_MOUSE Glycogen synthase kinase-3 alpha OS=Mus musculus OX=10090 GN=Gsk3a PE=1 SV=2 Length=490 Score = 79.3 bits (194), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 71/212 (33%), Positives = 104/212 (49%), Gaps = 35/212 (17%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I+ +G G FG V Y T E+VA+K + D ++R E+ I+R L H +I Sbjct 122 IKVIGNGSFGVV----YQARLAETRELVAIKKVLQDKRFKNR-----ELQIMRKLDHCNI 172 Query 960 IKYKGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRHSIGLAQLL-------LFAQQIC 1008 ++ + GEK L LV+EYVP R + RH A+L+ ++ Q+ Sbjct 173 VRLRYFFYSSGEKKDELYLNLVLEYVPETVYR--VARH-FTKAKLITPIIYIKVYMYQLF 229 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGH---EYYRVREDGDSP 1064 +AY+H+Q HRD+ +N+L+D D V K+ DFG AK + G Y R Sbjct 230 RSLAYIHSQGVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR------ 283 Query 1065 VFWYAPECLKEYKFYYAS-DVWSFGVTLYELL 1095 ++ APE + Y +S DVWS G L ELL Sbjct 284 -YYRAPELIFGATDYTSSIDVWSAGCVLAELL 314 Score = 35.0 bits (79), Expect = 4.5, Method: Compositional matrix adjust. Identities = 31/128 (24%), Positives = 58/128 (45%), Gaps = 12/128 (9%) Query 685 MVTEYVEHGPLDVW--LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +V EYV V + + P+ + V QL +L+Y+ ++ + H ++ +N+L+ Sbjct 193 LVLEYVPETVYRVARHFTKAKLITPIIYIKVYMYQLFRSLAYIHSQGVCHRDIKPQNLLV 252 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWG 799 + + +KL D G + E V I + APE + GA ++++D W Sbjct 253 ------DPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELI-FGATDYTSSIDVWS 305 Query 800 FGATLLEI 807 G L E+ Sbjct 306 AGCVLAEL 313 >sp|P34117|CDK5_DICDI Cyclin-dependent kinase 5 homolog OS=Dictyostelium discoideum OX=44689 GN=cdk5 PE=2 SV=2 Length=292 Score = 77.0 bits (188), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 63/201 (31%), Positives = 96/201 (48%), Gaps = 16/201 (8%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK-QEIDILRTLYHE 957 KI LGEG +G V Y N TGE+VA+K ++ D + +EI +L+ L H Sbjct 6 KIEKLGEGTYGIV----YKAKNRETGEIVALKRIRLDSEDEGVPCTAIREISLLKELKHP 61 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +I++ E+ L LV EY+ L+ YL I + F Q+ +G+A+ H Sbjct 62 NIVRLHDVI--HTERKLTLVFEYLD-QDLKKYLDECGGEISKPTIKSFMYQLLKGVAFCH 118 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074 +HRDL +N+L++ +K+ DFGLA+A Y + WY AP+ L Sbjct 119 DHRVLHRDLKPQNLLINRKGELKLADFGLARAFGIPVRTY----SHEVVTLWYRAPDVLM 174 Query 1075 -EYKFYYASDVWSFGVTLYEL 1094 K+ D+WS G E+ Sbjct 175 GSRKYSTPIDIWSAGCIFAEM 195 Score = 38.9 bits (89), Expect = 0.24, Method: Compositional matrix adjust. Identities = 49/224 (22%), Positives = 92/224 (41%), Gaps = 37/224 (17%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDP-EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 +++ LG+GT VY+ + R G + ++D ED VP Sbjct 5 SKIEKLGEGTYGIVYKAKNRETGEIVALKRIRLDSEDEGVP------------------- 45 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 A E SL+ ++ H ++ +H V + +V EY++ L +L G + Sbjct 46 ---CTAIREI-SLLKELKHPNIVRLHDVIHTERKLTLVFEYLDQD-LKKYLDECGGEISK 100 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GL 764 QL +++ + ++H ++ +N+L+ R G +KL+D G+ G+ Sbjct 101 PTIKSFMYQLLKGVAFCHDHRVLHRDLKPQNLLINRKGE-------LKLADFGLARAFGI 153 Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + V + + AP+ L G+ ST +D W G E+ Sbjct 154 PVRTYSHEVVTLWYRAPDVL-MGSRKYSTPIDIWSAGCIFAEMA 196 >sp|P50526|SSP1_SCHPO Serine/threonine-protein kinase ssp1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ssp1 PE=1 SV=1 Length=652 Score = 79.7 bits (195), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 64/221 (29%), Positives = 107/221 (48%), Gaps = 36/221 (16%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL----------KADCGPQHRSGWKQEID 949 I++LG G GKV L + T E++A+K + +A+ Q + ++EI Sbjct 138 IKELGRGMHGKVKL----GRDTVTRELLAIKIIPKTERRPKLGRANASSQ-KEKVRREIA 192 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR-DYLPRHSIGLAQLLLFAQQIC 1008 IL+ H ++++ + +D + LV+EY+ G + + +++ + + + Sbjct 193 ILKKCVHPNVVRLREVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQYFRDVV 252 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD------ 1062 G+ YLH Q IHRD+ N+LL++ VKI DFG++ G + ED D Sbjct 253 LGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIANAG-----LNEDNDVELAKT 307 Query 1063 --SPVFWYAPE-CLKEY-----KFYYASDVWSFGVTLYELL 1095 +P F +APE C + K A DVW+ GVTL+ LL Sbjct 308 VGTPAF-FAPELCWTDLDRPRPKISEAIDVWALGVTLFCLL 347 Score = 35.0 bits (79), Expect = 5.7, Method: Compositional matrix adjust. Identities = 44/154 (29%), Positives = 64/154 (42%), Gaps = 28/154 (18%) Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA---LSREERVERIP 777 L YL + ++H ++ N+LL +S +K+SD GV A L+ + VE Sbjct 254 GLEYLHYQGIIHRDIKPANLLL-------NSSNCVKISDFGVSYIANAGLNEDNDVELAK 306 Query 778 ------WLAPEC----LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 + APE L +S A+D W G TL + F G P + E E F Sbjct 307 TVGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLF-GRCPFN--ASMEYELFD 363 Query 828 Q-RQHRLPEPSCPQLA----TLTSQCLTYEPTQR 856 + RL PS P + L + L +P QR Sbjct 364 KIVNERLNIPSTPDIGEEGRDLLKRLLCKDPEQR 397 >sp|P51817|PRKX_HUMAN cAMP-dependent protein kinase catalytic subunit PRKX OS=Homo sapiens OX=9606 GN=PRKX PE=1 SV=1 Length=358 Score = 78.2 bits (191), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 63/228 (28%), Positives = 107/228 (47%), Gaps = 21/228 (9%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 A L +P++ + +P V+ + + +G G FG+V L + T + ALK Sbjct 27 APALCPSPEALSPEPPVYSLQDFDTLATVGTGTFGRVHL-----VKEKTAKHFF--ALKV 79 Query 935 DCGP-----QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 P + E +L+ + H +I+ D E+ L ++MEYVP G L Y Sbjct 80 MSIPDVIRLKQEQHVHNEKSVLKEVSHPFLIRLFWTWHD--ERFLYMLMEYVPGGELFSY 137 Query 990 L-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 L R L ++ +I + YLH++ ++RDL N+LLD D +K+ DFG AK + Sbjct 138 LRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKL 197 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 + R +P + APE ++ A D W+ G+ ++E+L+ Sbjct 198 VD-----RTWTLCGTPEY-LAPEVIQSKGHGRAVDWWALGILIFEMLS 239 Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 45/162 (28%), Positives = 71/162 (44%), Gaps = 12/162 (7%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S++ +VSH L + M+ EYV G L +LR RG + + ++ Sbjct 99 SVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRN-RGRFSSTTGLFYSAEII 157 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP-W 778 A+ YL +K +V+ ++ NILL R G IKL+D G + R + P + Sbjct 158 CAIEYLHSKEIVYRDLKPENILLDRDG-------HIKLTDFGFAKKLVDRTWTLCGTPEY 210 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 LAPE + + A+D W G + E+ G P +P Sbjct 211 LAPEVIQSKGH--GRAVDWWALGILIFEM-LSGFPPFFDDNP 249 >sp|Q5YJC2|GSK3B_SPECI Glycogen synthase kinase-3 beta OS=Spermophilus citellus OX=9997 GN=GSK3B PE=2 SV=1 Length=420 Score = 79.0 bits (193), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 70/208 (34%), Positives = 100/208 (48%), Gaps = 33/208 (16%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V Y +GE+VA+K + D ++R E+ I+R L H +I++ Sbjct 62 IGNGSFGVV----YQAKLCDSGELVAIKKVLQDKRFKNR-----ELQIMRKLDHCNIVRL 112 Query 963 KGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRHSIGLAQLL------LFAQQICEGMA 1012 + GEK L LV++YVP R + RH Q L L+ Q+ +A Sbjct 113 RYFFYSSGEKKDVVYLNLVLDYVPETVYR--VARHYSRAKQTLPVIYVKLYMYQLFRSLA 170 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGH---EYYRVREDGDSPVFWY 1068 Y+H+ HRD+ +N+LLD D V K+ DFG AK + G Y R ++ Sbjct 171 YIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR-------YYR 223 Query 1069 APECLKEYKFYYAS-DVWSFGVTLYELL 1095 APE + Y +S DVWS G L ELL Sbjct 224 APELIFGATDYTSSIDVWSAGCVLAELL 251 Score = 35.4 bits (80), Expect = 3.5, Method: Compositional matrix adjust. Identities = 27/110 (25%), Positives = 52/110 (47%), Gaps = 10/110 (9%) Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 R + +P+ + + QL +L+Y+ + + H ++ +N+LL + + +KL D Sbjct 148 RAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLL------DPDTAVLKLCDF 201 Query 761 GVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 G + E V I + APE + GA ++++D W G L E+ Sbjct 202 GSAKQLVRGEPNVSYICSRYYRAPELI-FGATDYTSSIDVWSAGCVLAEL 250 >sp|Q9FZB8|Y5181_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g51810 OS=Arabidopsis thaliana OX=3702 GN=At1g51810 PE=1 SV=1 Length=871 Score = 80.1 bits (196), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 71/236 (30%), Positives = 116/236 (49%), Gaps = 33/236 (14%) Query 883 DSPASDPTVFHKRYLKKI-------------RDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 DS +S+PT+ K KK + LG+G FG V Y + +GT E VAV Sbjct 552 DSRSSEPTIVTKN--KKFTYAEVLTMTNNFQKILGKGGFGIV----YYGSVNGT-EQVAV 604 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K L ++ +K E+++L ++H++++ G CE +G+K L L+ EY+ G L ++ Sbjct 605 KMLSHSSAQGYKQ-FKAEVELLLRVHHKNLVGLVGYCE-EGDK-LALIYEYMANGDLDEH 661 Query 990 LPRHSIG----LAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDF 1042 + G L A + +G+ YLH +HRD+ N+LL+ K+ DF Sbjct 662 MSGKRGGSILNWGTRLKIALEAAQGLEYLHNGCKPLMVHRDVKTTNILLNEHFDTKLADF 721 Query 1043 GLAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 GL+++ P EG + G + + PE + SDV+SFGV L ++T+ Sbjct 722 GLSRSFPIEGETHVSTVVAG--TIGYLDPEYYRTNWLTEKSDVYSFGVVLLVMITN 775 Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 60/213 (28%), Positives = 89/213 (42%), Gaps = 34/213 (16%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 G G E +V +K+L S F L+ +V H +L + G C G + ++ EY Sbjct 594 GSVNGTE-QVAVKMLSHSSAQGYKQFKAEVELLLRVHHKNLVGLVGYCEEGDKLALIYEY 652 Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLAR 744 + +G LD + +RG + W ++ +A + A L YL N +VH +V NILL Sbjct 653 MANGDLDEHMSGKRGGSILNWGTRLKIALEAAQGLEYLHNGCKPLMVHRDVKTTNILLNE 712 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVE-----------RIPWLAPECLPGGANSLST 793 KL+D G LSR +E I +L PE N L+ Sbjct 713 -------HFDTKLADFG-----LSRSFPIEGETHVSTVVAGTIGYLDPEYYR--TNWLTE 758 Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 D + FG LL + + Q+R EK H Sbjct 759 KSDVYSFGVVLLVMITNQPVIDQNR---EKRHI 788 >sp|A8X6H4|CMK1_CAEBR Calcium/calmodulin-dependent protein kinase type 1 OS=Caenorhabditis briggsae OX=6238 GN=cmk-1 PE=3 SV=4 Length=356 Score = 78.2 bits (191), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 66/218 (30%), Positives = 98/218 (45%), Gaps = 18/218 (8%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 ++PA ++ K + + LG G F KV L + G++ AVK + Sbjct 10 NTPAPTSSIREKYDFRDV--LGTGAFSKVFL---AESKTDVGQLYAVKCIDKKALKGKEE 64 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKS-LQLVMEYVPLGSLRD-YLPRHSIGLAQL 1000 + EI +LR L H +I++ E EK + LVME V G L D + + S Sbjct 65 SLENEIKVLRKLRHNNIVQ---LFETYDEKQFVYLVMELVTGGELFDRIVAKGSYTEQDA 121 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRV 1057 +Q+ E ++++H +HRDL N+L D D + I DFGL+K G V Sbjct 122 SNLIRQVLEAVSFMHDNGVVHRDLKPENLLYYNQDEDSKIMISDFGLSKTEDSG-----V 176 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 + APE L++ + A DVWS GV Y LL Sbjct 177 MATACGTPGYVAPEVLQQKPYGKAVDVWSIGVIAYILL 214 >sp|Q55GG4|Y9847_DICDI Probable serine/threonine-protein kinase DDB_G0267686 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0267686 PE=3 SV=1 Length=2230 Score = 80.5 bits (197), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 71/284 (25%), Positives = 127/284 (45%), Gaps = 28/284 (10%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 + LGEG KV + + VAVK L+++ Q + +E++I+ +L H+ Sbjct 1952 LNKLGEGTSAKVYRATW------RNQEVAVKVLRSEPESQKLLDFLKELEIMSSLRSPHV 2005 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQH 1018 + + G D + ++MEY +L + + + + FA ++ G+ LH+ Sbjct 2006 VYFYGMVLD---PKICMIMEYCSNQTLYHLMHLQMNFTWDWVFKFAIEMVRGVNCLHSWK 2062 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLKE 1075 +HRDL + N+L+ ++ +K+ DFGL++ R F Y APE Sbjct 2063 PVIVHRDLKSLNLLVSDNWTIKVADFGLSRFATAKSASNRTTRG----TFAYCAPEVF-- 2116 Query 1076 YKFYYAS-DVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 Y + D++S G+ L+EL C S + P ++F + Q L + + Sbjct 2117 YGIHTTKGDIFSIGIILWELAVRCIKSKYEKPFSEFKHI------QYDFQILVQTSKFNL 2170 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 R P CP +L+ NCWE+ RP+ ++ L + +KY Sbjct 2171 RPTIPQNCPEAFSNLISNCWESSPDNRPSCPEILDSLLDMEKKY 2214 Score = 38.9 bits (89), Expect = 0.38, Method: Compositional matrix adjust. Identities = 68/306 (22%), Positives = 118/306 (39%), Gaps = 57/306 (19%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 +D +EI L+ LG+GT VY R QE+ V + Sbjct 1944 IDGEEIVFLNKLGEGTSAKVYRATW------------------------RNQEVAVKVLR 1979 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 +P + L F + +MS + H+ + +G+ V P+ M+ EY + L L + Sbjct 1980 SEPESQKL-LDFLKELEIMSSLRSPHVVYFYGM-VLDPKICMIMEYCSNQTL-YHLMHLQ 2036 Query 704 GHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 + W A ++ ++ L + +VH ++ N+L++ + IK++D G Sbjct 2037 MNFTWDWVFKFAIEMVRGVNCLHSWKPVIVHRDLKSLNLLVSD-------NWTIKVADFG 2089 Query 762 VG--LGALSREERVER--IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + A S R R + APE G +T D + G L E+ Sbjct 2090 LSRFATAKSASNRTTRGTFAYCAPEVFYGIH---TTKGDIFSIGIILWELAVRCIKSKYE 2146 Query 818 RSPSEKEHF------------YQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILR 864 + SE +H + + +P+ +CP+ + L S C P RPS IL Sbjct 2147 KPFSEFKHIQYDFQILVQTSKFNLRPTIPQ-NCPEAFSNLISNCWESSPDNRPSCPEILD 2205 Query 865 DLTRLQ 870 L ++ Sbjct 2206 SLLDME 2211 >sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo sapiens OX=9606 GN=SIK2 PE=1 SV=1 Length=926 Score = 80.1 bits (196), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 63/196 (32%), Positives = 91/196 (46%), Gaps = 13/196 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG+G+F V L + T VA+K + K+ + +E+ I++ L H HIIK Sbjct 26 LGKGNFAVVKLGRHRITKTE----VAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIK 81 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020 E + L LV EY G + DYL H + ++ QI + Y H + + Sbjct 82 LYQVMETKS--MLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIV 139 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDL A N+LLDN+ +KI DFG G G P + APE + ++ Sbjct 140 HRDLKAENLLLDNNMNIKIADFGFGNFFKSGE--LLATWCGSPP--YAAPEVFEGQQYEG 195 Query 1081 AS-DVWSFGVTLYELL 1095 D+WS GV LY L+ Sbjct 196 PQLDIWSMGVVLYVLV 211 Score = 47.8 bits (112), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 49/192 (26%), Positives = 79/192 (41%), Gaps = 19/192 (10%) Query 630 GRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 GR R + V +K++D S D Y +M + H H+ ++ V +VT Sbjct 37 GRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVT 96 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 EY ++G + +L G + + Q+ SA+ Y + +VH ++ N+LL Sbjct 97 EYAKNGEIFDYLAN-HGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLL----- 150 Query 748 AEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGATL 804 + IK++D G G S E P+ APE G +D W G L Sbjct 151 --DNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYE-GPQLDIWSMGVVL 207 Query 805 -LEIC----FDG 811 + +C FDG Sbjct 208 YVLVCGALPFDG 219 >sp|O54784|DAPK3_MOUSE Death-associated protein kinase 3 OS=Mus musculus OX=10090 GN=Dapk3 PE=1 SV=1 Length=448 Score = 79.0 bits (193), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 63/205 (31%), Positives = 99/205 (48%), Gaps = 20/205 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-----WKQEIDILRTLYH 956 +LG G F V C GTG A K +K P R G ++E+ ILR + H Sbjct 18 ELGSGQFAIVR-KC---QQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIRH 73 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLH 1015 +II E++ + + L++E V G L D+L + S+ + F +QI +G+ YLH Sbjct 74 PNIITLHDVFENKTD--VVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131 Query 1016 AQHYIHRDLAARNVLLDNDRL----VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 ++ H DL N++L + +K+ DFG+A + G E+ + +P F APE Sbjct 132 SKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNI---FGTPEF-VAPE 187 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 + +D+WS GV Y LL+ Sbjct 188 IVNYEPLGLEADMWSIGVITYILLS 212 Score = 37.7 bits (86), Expect = 0.59, Method: Compositional matrix adjust. Identities = 39/166 (23%), Positives = 71/166 (43%), Gaps = 10/166 (6%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S++ ++ H ++ +H V + +++ E V G L +L E+ + +Q+ Sbjct 66 SILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLA-EKESLTEDEATQFLKQIL 124 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIP 777 + YL +K + H ++ NI+L SP IKL D G+ + A S + + P Sbjct 125 DGVHYLHSKRIAHFDLKPENIMLLD---KHAASPRIKLIDFGIAHRIEAGSEFKNIFGTP 181 Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 ++APE + L D W G + I G +P + E Sbjct 182 EFVAPEIV--NYEPLGLEADMWSIG-VITYILLSGASPFLGETKQE 224 >sp|Q9C7T7|CEPR2_ARATH Receptor protein-tyrosine kinase CEPR2 OS=Arabidopsis thaliana OX=3702 GN=CEPR2 PE=1 SV=1 Length=977 Score = 80.1 bits (196), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 69/213 (32%), Positives = 98/213 (46%), Gaps = 37/213 (17%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ--EIDILRTLYHEHII 960 +G G GKV Y G VAVK LK G + E++IL + H +++ Sbjct 689 IGSGSAGKV----YRVDLKKGGGTVAVKWLKRGGGEEGDGTEVSVAEMEILGKIRHRNVL 744 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLR--------------DYLPRHSIGLAQLLLFAQQ 1006 K C +G + LV E++ G+L D+L R+ I + Sbjct 745 KLYACLVGRGSR--YLVFEFMENGNLYQALGNNIKGGLPELDWLKRYKIAVGA------- 795 Query 1007 ICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 +G+AYLH IHRD+ + N+LLD D KI DFG+AK +G+E+ V Sbjct 796 -AKGIAYLHHDCCPPIIHRDIKSSNILLDGDYESKIADFGVAKVADKGYEWSCVAGTHG- 853 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 + APE +K SDV+SFGV L EL+T Sbjct 854 ---YMAPELAYSFKATEKSDVYSFGVVLLELVT 883 >sp|Q9SKB2|SBIR1_ARATH Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 OS=Arabidopsis thaliana OX=3702 GN=SOBIR1 PE=1 SV=1 Length=641 Score = 79.7 bits (195), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 50/124 (40%), Positives = 66/124 (53%), Gaps = 9/124 (7%) Query 976 LVMEYVPLGSLRDYLPRHSIGLAQLL-----LFAQQICEGMAYLHAQH---YIHRDLAAR 1027 LV EY+ GSL+D L G +L+ A I G+ YLH H IHRDL Sbjct 434 LVYEYMEKGSLQDILTDVQAGNQELMWPARHKIALGIAAGLEYLHMDHNPRIIHRDLKPA 493 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 NVLLD+D +I DFGLAKA+P+ + + V + APE + +KF D++SF Sbjct 494 NVLLDDDMEARISDFGLAKAMPDAVTHITTSHVAGT-VGYIAPEFYQTHKFTDKCDIYSF 552 Query 1088 GVTL 1091 GV L Sbjct 553 GVIL 556 >sp|Q7XR88|STRK1_ORYSJ Salt tolerance receptor-like cytoplasmic kinase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=STRK1 PE=1 SV=2 Length=361 Score = 78.2 bits (191), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 68/211 (32%), Positives = 101/211 (48%), Gaps = 27/211 (13%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEH 958 R +G G F V L + G A+K C + HR+ ++QE+++L +L H H Sbjct 71 RVIGHGGFSTVYLASLSSSRLG--------AVKVHCSSERLHRA-FRQELEVLLSLRHPH 121 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI--GLAQLLLFAQ------QICEG 1010 I++ G C+++ E LV EY P G L + L + G+A +L +A+ Q+ Sbjct 122 IVRLLGYCDERDEG--VLVFEYAPNGDLHERLHCSEVAGGVASVLPWARRVAIAFQVAMA 179 Query 1011 MAYLHAQHY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--VREDGDSPV 1065 + YLH + IH D+ A NVLLD + K+ DFG A R R SP Sbjct 180 LEYLHESRHPAVIHGDIKASNVLLDANMNAKLCDFGFAHVGFSATVGCRPSARAVMGSP- 238 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 + P ++ SDV+SFGV L EL+T Sbjct 239 GYVDPHLIRSGVATKKSDVYSFGVLLLELVT 269 Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust. Identities = 61/251 (24%), Positives = 97/251 (39%), Gaps = 54/251 (22%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-------- 705 AF + ++ + H H+ + G C E ++V EY +G L ER H Sbjct 106 AFRQELEVLLSLRHPHIVRLLGYCDERDEGVLVFEYAPNGDL-----HERLHCSEVAGGV 160 Query 706 ---VPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 +P A ++ +A Q+A AL YL ++HG++ N+LL + KL D Sbjct 161 ASVLPWARRVAIAFQVAMALEYLHESRHPAVIHGDIKASNVLL-------DANMNAKLCD 213 Query 760 PG---VGLGAL-----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G VG A S + ++ P + G + + D + FG LLE+ Sbjct 214 FGFAHVGFSATVGCRPSARAVMGSPGYVDPHLIRSGVATKKS--DVYSFGVLLLELVTGK 271 Query 812 EAPLQSR------------SPSEKEHFYQR----QHRLPEPSCPQLATLTSQCLTYEPTQ 855 EA + S + R +H E + +A L QC+ P Sbjct 272 EAVCRDTGRRLTAAVGPMLSEGKVADVVDRRLGGEHDGAEAAV--MAELAMQCIGDSPGL 329 Query 856 RPSFRTILRDL 866 RPS ++R L Sbjct 330 RPSMADVVRAL 340 >sp|A2XW02|STRK1_ORYSI Salt tolerance receptor-like cytoplasmic kinase 1 OS=Oryza sativa subsp. indica OX=39946 GN=OsI_16820 PE=2 SV=1 Length=361 Score = 78.2 bits (191), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 68/211 (32%), Positives = 101/211 (48%), Gaps = 27/211 (13%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEH 958 R +G G F V L + G A+K C + HR+ ++QE+++L +L H H Sbjct 71 RVIGHGGFSTVYLASLSSSRLG--------AVKVHCSSERLHRA-FRQELEVLLSLRHPH 121 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI--GLAQLLLFAQ------QICEG 1010 I++ G C+++ E LV EY P G L + L + G+A +L +A+ Q+ Sbjct 122 IVRLLGYCDERDEG--VLVFEYAPNGDLHERLHCSEVAGGVASVLPWARRVAIAFQVAMA 179 Query 1011 MAYLHAQHY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--VREDGDSPV 1065 + YLH + IH D+ A NVLLD + K+ DFG A R R SP Sbjct 180 LEYLHESRHPAVIHGDIKASNVLLDANMNAKLCDFGFAHVGFSATVGCRPSARAVMGSP- 238 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 + P ++ SDV+SFGV L EL+T Sbjct 239 GYVDPHLIRSGVATKKSDVYSFGVLLLELVT 269 Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust. Identities = 61/251 (24%), Positives = 97/251 (39%), Gaps = 54/251 (22%) Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-------- 705 AF + ++ + H H+ + G C E ++V EY +G L ER H Sbjct 106 AFRQELEVLLSLRHPHIVRLLGYCDERDEGVLVFEYAPNGDL-----HERLHCSEVAGGV 160 Query 706 ---VPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 +P A ++ +A Q+A AL YL ++HG++ N+LL + KL D Sbjct 161 ASVLPWARRVAIAFQVAMALEYLHESRHPAVIHGDIKASNVLL-------DANMNAKLCD 213 Query 760 PG---VGLGAL-----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G VG A S + ++ P + G + + D + FG LLE+ Sbjct 214 FGFAHVGFSATVGCRPSARAVMGSPGYVDPHLIRSGVATKKS--DVYSFGVLLLELVTGK 271 Query 812 EAPLQSR------------SPSEKEHFYQR----QHRLPEPSCPQLATLTSQCLTYEPTQ 855 EA + S + R +H E + +A L QC+ P Sbjct 272 EAVCRDTGRRLTAAVGPMLSEGKVADVVDRRLGGEHDGAEAAV--MAELAMQCIGDSPGL 329 Query 856 RPSFRTILRDL 866 RPS ++R L Sbjct 330 RPSMADVVRAL 340 >sp|P48609|CDK5_DROME Cyclin-dependent kinase 5 homolog OS=Drosophila melanogaster OX=7227 GN=Cdk5 PE=1 SV=2 Length=294 Score = 77.0 bits (188), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 62/201 (31%), Positives = 101/201 (50%), Gaps = 16/201 (8%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957 K+ +GEG +G V + N T E+VA+K ++ D + S +EI +L+ L H+ Sbjct 6 KMEKIGEGTYGTV----FKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHK 61 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015 +I++ +K L LV E+ L+ Y + I +A F Q+ G+A+ H Sbjct 62 NIVRLIDVL--HSDKKLTLVFEHCD-QDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCH 118 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA-PECLK 1074 + + +HRDL +N+L++ + +K+ DFGLA+A + Y + WY P+ L Sbjct 119 SHNVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVKCY----SAEVVTLWYRPPDVLF 174 Query 1075 EYKFYYAS-DVWSFGVTLYEL 1094 K Y S D+WS G L EL Sbjct 175 GAKLYTTSIDMWSAGCILAEL 195 >sp|P49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta OS=Homo sapiens OX=9606 GN=GSK3B PE=1 SV=2 Length=420 Score = 78.6 bits (192), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 70/208 (34%), Positives = 100/208 (48%), Gaps = 33/208 (16%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V Y +GE+VA+K + D ++R E+ I+R L H +I++ Sbjct 62 IGNGSFGVV----YQAKLCDSGELVAIKKVLQDKRFKNR-----ELQIMRKLDHCNIVRL 112 Query 963 KGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRHSIGLAQLL------LFAQQICEGMA 1012 + GEK L LV++YVP R + RH Q L L+ Q+ +A Sbjct 113 RYFFYSSGEKKDEVYLNLVLDYVPETVYR--VARHYSRAKQTLPVIYVKLYMYQLFRSLA 170 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGH---EYYRVREDGDSPVFWY 1068 Y+H+ HRD+ +N+LLD D V K+ DFG AK + G Y R ++ Sbjct 171 YIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR-------YYR 223 Query 1069 APECLKEYKFYYAS-DVWSFGVTLYELL 1095 APE + Y +S DVWS G L ELL Sbjct 224 APELIFGATDYTSSIDVWSAGCVLAELL 251 Score = 35.8 bits (81), Expect = 2.7, Method: Compositional matrix adjust. Identities = 27/110 (25%), Positives = 52/110 (47%), Gaps = 10/110 (9%) Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 R + +P+ + + QL +L+Y+ + + H ++ +N+LL + + +KL D Sbjct 148 RAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLL------DPDTAVLKLCDF 201 Query 761 GVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 G + E V I + APE + GA ++++D W G L E+ Sbjct 202 GSAKQLVRGEPNVSYICSRYYRAPELI-FGATDYTSSIDVWSAGCVLAEL 250 >sp|Q14164|IKKE_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit epsilon OS=Homo sapiens OX=9606 GN=IKBKE PE=1 SV=1 Length=716 Score = 79.7 bits (195), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 61/206 (30%), Positives = 95/206 (46%), Gaps = 16/206 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G V Y N +GE+VAVK + R +E ++LR L H++I+K Sbjct 15 LGQGATASV----YKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLRKLNHQNIVKL 70 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGL--AQLLLFAQQICEGMAYLHAQH 1018 E G + LVMEY GSL L P ++ GL + L+ + + GM +L Sbjct 71 FAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVVAGMNHLRENG 130 Query 1019 YIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPEC 1072 +HRD+ N++ + + K+ DFG A+ + + ++ V E+ P + Sbjct 131 IVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYLHPDMYERAVL 190 Query 1073 LK--EYKFYYASDVWSFGVTLYELLT 1096 K + F D+WS GVTLY T Sbjct 191 RKPQQKAFGVTVDLWSIGVTLYHAAT 216 >sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens OX=9606 GN=RPS6KA3 PE=1 SV=1 Length=740 Score = 79.7 bits (195), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 62/212 (29%), Positives = 109/212 (51%), Gaps = 13/212 (6%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWK 945 +DP+ F + ++ LG+G FGKV L +D ++ A+K LK A + R K Sbjct 63 ADPSQF-----ELLKVLGQGSFGKVFLVKKISGSDAR-QLYAMKVLKKATLKVRDRVRTK 116 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ-LLLFA 1004 E DIL + H I+K + +G+ L L+++++ G L L + + + + + Sbjct 117 MERDILVEVNHPFIVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYL 174 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 ++ + +LH+ I+RDL N+LLD + +K+ DFGL+K E ++ + Sbjct 175 AELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK---ESIDHEKKAYSFCGT 231 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 V + APE + ++D WSFGV ++E+LT Sbjct 232 VEYMAPEVVNRRGHTQSADWWSFGVLMFEMLT 263 Score = 65.5 bits (158), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 62/185 (34%), Positives = 87/185 (47%), Gaps = 29/185 (16%) Query 946 QEIDIL-RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLL 1001 +EI+IL R H +II K +D K + +V E + G L D + R S A + Sbjct 462 EEIEILLRYGQHPNIITLKDVYDDG--KYVYVVTELMKGGELLDKILRQKFFSEREASAV 519 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRV 1057 LF I + + YLHAQ +HRDL N+L N ++I DFG AK + Sbjct 520 LFT--ITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRA------- 570 Query 1058 REDG--DSPVF---WYAPECLKEYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKF 1108 E+G +P + + APE LK + A D+WS GV LY +LT + P + Sbjct 571 -ENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEI 629 Query 1109 LELIG 1113 L IG Sbjct 630 LARIG 634 >sp|O95819|M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP4K4 PE=1 SV=2 Length=1239 Score = 80.5 bits (197), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 58/205 (28%), Positives = 99/205 (48%), Gaps = 22/205 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961 +G G +G+V Y + TG++ A+K + D K EI++L+ +H +I Sbjct 31 VGNGTYGQV----YKGRHVKTGQLAAIKVM--DVTEDEEEEIKLEINMLKKYSHHRNIAT 84 Query 962 YKGCCEDQG----EKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYL 1014 Y G + + L LVME+ GS+ D + +++ + +++I G+A+L Sbjct 85 YYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHL 144 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H H IHRD+ +NVLL + VK+ DFG++ + R +W APE + Sbjct 145 HIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---DRTVGRRNTFIGTPYWMAPEVIA 201 Query 1075 -----EYKFYYASDVWSFGVTLYEL 1094 + + Y SD+WS G+T E+ Sbjct 202 CDENPDATYDYRSDLWSCGITAIEM 226 Score = 41.2 bits (95), Expect = 0.073, Method: Compositional matrix adjust. Identities = 55/253 (22%), Positives = 99/253 (39%), Gaps = 32/253 (13%) Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP------ENIMVTEYVEHGP 694 +KV+D + + E L H ++A +G ++ + +V E+ G Sbjct 53 IKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGS 112 Query 695 LDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 + ++ +G+ + W +++++ L++L +++H ++ G+N+LL + Sbjct 113 ITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTE-------NA 165 Query 754 FIKLSDPGVGLG---ALSREERVERIP-WLAPECLPGGANSLST---AMDKWGFGATLLE 806 +KL D GV + R P W+APE + N +T D W G T +E Sbjct 166 EVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIE 225 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ------CLTYEPTQRPSFR 860 + +G PL P R P P CL QRPS Sbjct 226 MA-EGAPPLCDMHPMRALFLIPRN---PPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTE 281 Query 861 TILRD-LTRLQPH 872 +L+ R QP+ Sbjct 282 QLLKHPFIRDQPN 294 >sp|P18654|KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 OS=Mus musculus OX=10090 GN=Rps6ka3 PE=1 SV=2 Length=740 Score = 79.7 bits (195), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 62/212 (29%), Positives = 109/212 (51%), Gaps = 13/212 (6%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWK 945 +DP+ F + ++ LG+G FGKV L +D ++ A+K LK A + R K Sbjct 63 ADPSQF-----ELLKVLGQGSFGKVFLVKKISGSDAR-QLYAMKVLKKATLKVRDRVRTK 116 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ-LLLFA 1004 E DIL + H I+K + +G+ L L+++++ G L L + + + + + Sbjct 117 MERDILVEVNHPFIVKLHYAFQTEGK--LYLILDFLRGGDLFTRLSKEVMFTEEDVKFYL 174 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 ++ + +LH+ I+RDL N+LLD + +K+ DFGL+K E ++ + Sbjct 175 AELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK---ESIDHEKKAYSFCGT 231 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 V + APE + ++D WSFGV ++E+LT Sbjct 232 VEYMAPEVVNRRGHTQSADWWSFGVLMFEMLT 263 Score = 65.5 bits (158), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 62/185 (34%), Positives = 87/185 (47%), Gaps = 29/185 (16%) Query 946 QEIDIL-RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLL 1001 +EI+IL R H +II K +D K + +V E + G L D + R S A + Sbjct 462 EEIEILLRYGQHPNIITLKDVYDDG--KYVYVVTELMKGGELLDKILRQKFFSEREASAV 519 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRV 1057 LF I + + YLHAQ +HRDL N+L N ++I DFG AK + Sbjct 520 LFT--ITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRA------- 570 Query 1058 REDG--DSPVF---WYAPECLKEYKFYYASDVWSFGVTLYELLT----HCDSSQSPPTKF 1108 E+G +P + + APE LK + A D+WS GV LY +LT + P + Sbjct 571 -ENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEI 629 Query 1109 LELIG 1113 L IG Sbjct 630 LARIG 634 >sp|Q9WV60|GSK3B_MOUSE Glycogen synthase kinase-3 beta OS=Mus musculus OX=10090 GN=Gsk3b PE=1 SV=2 Length=420 Score = 78.6 bits (192), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 70/208 (34%), Positives = 100/208 (48%), Gaps = 33/208 (16%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V Y +GE+VA+K + D ++R E+ I+R L H +I++ Sbjct 62 IGNGSFGVV----YQAKLCDSGELVAIKKVLQDKRFKNR-----ELQIMRKLDHCNIVRL 112 Query 963 KGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRHSIGLAQLL------LFAQQICEGMA 1012 + GEK L LV++YVP R + RH Q L L+ Q+ +A Sbjct 113 RYFFYSSGEKKDEVYLNLVLDYVPETVYR--VARHYSRAKQTLPVIYVKLYMYQLFRSLA 170 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGH---EYYRVREDGDSPVFWY 1068 Y+H+ HRD+ +N+LLD D V K+ DFG AK + G Y R ++ Sbjct 171 YIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSR-------YYR 223 Query 1069 APECLKEYKFYYAS-DVWSFGVTLYELL 1095 APE + Y +S DVWS G L ELL Sbjct 224 APELIFGATDYTSSIDVWSAGCVLAELL 251 Score = 35.8 bits (81), Expect = 2.6, Method: Compositional matrix adjust. Identities = 27/110 (25%), Positives = 52/110 (47%), Gaps = 10/110 (9%) Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 R + +P+ + + QL +L+Y+ + + H ++ +N+LL + + +KL D Sbjct 148 RAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLL------DPDTAVLKLCDF 201 Query 761 GVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 G + E V I + APE + GA ++++D W G L E+ Sbjct 202 GSAKQLVRGEPNVSYICSRYYRAPELI-FGATDYTSSIDVWSAGCVLAEL 250 >sp|P28867|KPCD_MOUSE Protein kinase C delta type OS=Mus musculus OX=10090 GN=Prkcd PE=1 SV=3 Length=674 Score = 79.7 bits (195), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 66/216 (31%), Positives = 100/216 (46%), Gaps = 37/216 (17%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FGKV L G + A+K LK D + D+ T+ + ++ Sbjct 353 LGKGSFGKVLL----AELKGKDKYFAIKCLKKDVVLI-------DDDVECTMVEKRVLAL 401 Query 963 KG--------CCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAY 1013 C Q + L VME++ G L ++ + L + +A +I G+ + Sbjct 402 AWESPFLTHLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQF 461 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WY 1068 LH++ I+RDL NV+LD D +KI DFG+ K G +G + F + Sbjct 462 LHSKGIIYRDLKLDNVMLDRDGHIKIADFGMCKENIFG--------EGRASTFCGTPDYI 513 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 APE L+ K+ ++ D WSFGV LYE+L QSP Sbjct 514 APEILQGLKYSFSVDWWSFGVLLYEMLI----GQSP 545 >sp|P54666|CC2H3_TRYBB Cell division control protein 2 homolog 3 OS=Trypanosoma brucei brucei OX=5702 GN=CRK3 PE=3 SV=1 Length=311 Score = 77.4 bits (189), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 67/202 (33%), Positives = 96/202 (48%), Gaps = 26/202 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ----EIDILRTLYHEH 958 LGEG +G V Y + TG++VA+K ++ D + G Q E+ IL+ ++H + Sbjct 29 LGEGTYGVV----YRAVDRATGQIVALKKVRLD---RTDEGIPQTALREVSILQEIHHPN 81 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--FAQQICEGMAYLHA 1016 I+ G+ L L+ EYV L+ L + L Q+ EG+++ H Sbjct 82 IVNLLDVICADGK--LYLIFEYVD-HDLKKALEKRGGAFTGTTLKKIIYQLLEGLSFCHR 138 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-APECL 1073 +HRDL N+L+ D VKI DFGLA+A +P H Y + WY APE L Sbjct 139 HRIVHRDLKPANILVTTDNSVKIADFGLARAFQIPM-HTYTH-----EVVTLWYRAPEIL 192 Query 1074 KEYKFYY-ASDVWSFGVTLYEL 1094 K Y A D+WS G EL Sbjct 193 LGEKHYTPAVDMWSIGCIFAEL 214 Score = 37.0 bits (84), Expect = 1.00, Method: Compositional matrix adjust. Identities = 57/269 (21%), Positives = 100/269 (37%), Gaps = 44/269 (16%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 R GQ + + LD + I S++ ++ H ++ + V + ++ EYV Sbjct 43 RATGQIVALKKVRLDRTDEGIPQTALREVSILQEIHHPNIVNLLDVICADGKLYLIFEYV 102 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 +H +R K ++ QL LS+ +VH ++ NIL+ Sbjct 103 DHDLKKALEKRGGAFTGTTLKKII-YQLLEGLSFCHRHRIVHRDLKPANILVT------- 154 Query 751 TSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 T +K++D G+ + + V + + APE L G + A+D W G E Sbjct 155 TDNSVKIADFGLARAFQIPMHTYTHEVVTLWYRAPEILL-GEKHYTPAVDMWSIGCIFAE 213 Query 807 -----ICFDGEAPLQSR--------SPSEKEHFYQRQHRLPE-----------PSCPQLA 842 + F G++ + +P + E + LP+ P L Sbjct 214 LARGKVLFRGDSEIGQLFEIFQVLGTPMDAEGSWLGVSSLPDYRDVFPKWSGKPLTQVLP 273 Query 843 TLT-------SQCLTYEPTQRPSFRTILR 864 TL SQ L Y P +R S + L+ Sbjct 274 TLDGDAVDLLSQMLRYNPAERISAKAALQ 302 >sp|Q9C8I6|IOS1_ARATH LRR receptor-like serine/threonine-protein kinase IOS1 OS=Arabidopsis thaliana OX=3702 GN=IOS1 PE=1 SV=1 Length=894 Score = 80.1 bits (196), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 75/279 (27%), Positives = 128/279 (46%), Gaps = 22/279 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R LG G FG V Y N+ E VAVK L ++ +K E+++L ++H+ + Sbjct 590 RVLGRGGFGVV---YYGVLNN---EPVAVKMLTESTALGYKQ-FKAEVELLLRVHHKDLT 642 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA 1016 G CE +G+K + L+ E++ G L+++L + L A + +G+ YLH Sbjct 643 CLVGYCE-EGDK-MSLIYEFMANGDLKEHLSGKRGPSILTWEGRLRIAAESAQGLEYLHN 700 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +HRD+ N+LL+ K+ DFGL+++ P G E + +P + PE Sbjct 701 GCKPQIVHRDIKTTNILLNEKFQAKLADFGLSRSFPLGTETHVSTIVAGTPGY-LDPEYY 759 Query 1074 KEYKFYYASDVWSFGVTLYELLTH--CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + SDV+SFGV L EL+T+ + + E +G+ + + + + +G Sbjct 760 RTNWLTEKSDVFSFGVVLLELVTNQPVIDMKREKSHIAEWVGLMLSRGDINSIVDPKLQG 819 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + P +V C +S RPT ++ LK Sbjct 820 DFDP---NTIWKVVETAMTCLNPSSSRRPTMTQVVMDLK 855 Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust. Identities = 51/181 (28%), Positives = 77/181 (43%), Gaps = 20/181 (11%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K+L S F L+ +V H L + G C G + ++ E++ +G L Sbjct 610 VAVKMLTESTALGYKQFKAEVELLLRVHHKDLTCLVGYCEEGDKMSLIYEFMANGDLKEH 669 Query 699 LRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSP 753 L +RG + W ++ +A + A L YL N +VH ++ NILL A Sbjct 670 LSGKRGPSILTWEGRLRIAAESAQGLEYLHNGCKPQIVHRDIKTTNILLNEKFQA----- 724 Query 754 FIKLSDPGVGLG-ALSREERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 KL+D G+ L E V I +L PE N L+ D + FG LLE+ Sbjct 725 --KLADFGLSRSFPLGTETHVSTIVAGTPGYLDPEYYR--TNWLTEKSDVFSFGVVLLEL 780 Query 808 C 808 Sbjct 781 V 781 >sp|Q9QUK0|CDKL2_MOUSE Cyclin-dependent kinase-like 2 OS=Mus musculus OX=10090 GN=Cdkl2 PE=2 SV=1 Length=568 Score = 79.3 bits (194), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 60/198 (30%), Positives = 101/198 (51%), Gaps = 16/198 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG +G V + C N +G +VA+K L++D + +EI +L+ L HE+++ Sbjct 10 VGEGSYGMV-MKC---RNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65 Query 962 YKGCCEDQGEKSLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 C+ + K LV E+V L L+ + + Q LF QI G+ + H+ + Sbjct 66 LLEVCKKK--KRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLF--QIINGIGFCHSHN 121 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEYK 1077 IHRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L + K Sbjct 122 IIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVK 178 Query 1078 FYYASDVWSFGVTLYELL 1095 + A D+W+ G + E+L Sbjct 179 YGKAVDIWAIGCLVIEML 196 Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 60/245 (24%), Positives = 101/245 (41%), Gaps = 54/245 (22%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ---- 716 L+ Q+ H +L + VC + +V E+V+H LD + P V Q Sbjct 54 LLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILD-----DLKLFPNGLDYQVVQKYLF 108 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVER 775 Q+ + + + + N++H ++ NIL+++ G+ +KL D G A E + Sbjct 109 QIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFARTLAAPGEVYTDY 161 Query 776 IP---WLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGEAP----------LQS 817 + + APE L G A+D W G ++E+ F GE+ L + Sbjct 162 VATRWYRAPELLVGDV-KYGKAVDIWAIGCLVIEMLMGQPLFPGESDIDQLHHIMTCLGN 220 Query 818 RSPSEKEHFYQR----QHRLPE-------------PSCPQ-LATLTSQCLTYEPTQRPSF 859 P +E FY+ RLPE P P+ + +L +CL +P +RP Sbjct 221 LIPRHQELFYKNPVFAGVRLPEVKDAEAEPLESRYPKLPEAVISLAKKCLHIDPDKRPFC 280 Query 860 RTILR 864 +LR Sbjct 281 ADLLR 285 >sp|Q93Z30|BHP_ARATH Serine/threonine-protein kinase 12 OS=Arabidopsis thaliana OX=3702 GN=BHP PE=1 SV=1 Length=459 Score = 79.0 bits (193), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 73/268 (27%), Positives = 118/268 (44%), Gaps = 48/268 (18%) Query 924 GEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 G VAVK L + + E+ +L+ L H +I+++ G + +V EY+ Sbjct 178 GIQVAVKKLDDEVLSDDDQVRKFHDELALLQRLRHPNIVQFLGAVTQSN--PMMIVTEYL 235 Query 982 PLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLV 1037 P G LR+ L R + A + +A I GM+YLH IHRDL N+L D+ + Sbjct 236 PRGDLRELLKRKGQLKPATAVRYALDIARGMSYLHEIKGDPIIHRDLEPSNILRDDSGHL 295 Query 1038 KIGDFGLAKAVPEGHEYYRVREDG-----DSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 K+ DFG++K V V+ED D + APE ++ +DV+SF + + Sbjct 296 KVADFGVSKLVT-------VKEDKPFTCQDISCRYIAPEVFTSEEYDTKADVFSFALIVQ 348 Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL--TELLERGERLPRP-DKCPCEVY---- 1145 E++ +G+M +E E RP K P + Y Sbjct 349 EMI--------------------EGRMPFAEKEDSEASEAYAGKHRPLFKAPSKNYPHGL 388 Query 1146 -HLMKNCWETEASFRPTFENLIPILKTV 1172 L++ CW + + RPTF +I L+++ Sbjct 389 KTLIEECWHEKPAKRPTFREIIKRLESI 416 Score = 68.6 bits (166), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 64/252 (25%), Positives = 114/252 (45%), Gaps = 27/252 (11%) Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 ++V +K LD S D F++ +L+ ++ H ++ G + ++VTEY+ G Sbjct 179 IQVAVKKLDDEVLSDDDQVRKFHDELALLQRLRHPNIVQFLGAVTQSNPMMIVTEYLPRG 238 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYL---ENKNLVHGNVCGRNILLARLGLAEG 750 L L+R +G + A + A +A +SYL + ++H ++ NIL Sbjct 239 DLRELLKR-KGQLKPATAVRYALDIARGMSYLHEIKGDPIIHRDLEPSNIL-------RD 290 Query 751 TSPFIKLSDPGVGLGALSREER---VERIP--WLAPECLPGGANSLSTAMDKWGFGATLL 805 S +K++D GV +E++ + I ++APE + T D + F + Sbjct 291 DSGHLKVADFGVSKLVTVKEDKPFTCQDISCRYIAPEVF--TSEEYDTKADVFSFALIVQ 348 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHR----LPEPSCPQ-LATLTSQCLTYEPTQRPSFR 860 E+ +G P + SE Y +HR P + P L TL +C +P +RP+FR Sbjct 349 EM-IEGRMPFAEKEDSEASEAYAGKHRPLFKAPSKNYPHGLKTLIEECWHEKPAKRPTFR 407 Query 861 TILRDLTRLQPH 872 I++ L + H Sbjct 408 EIIKRLESILHH 419 >sp|Q8BG48|ST17B_MOUSE Serine/threonine-protein kinase 17B OS=Mus musculus OX=10090 GN=Stk17b PE=1 SV=1 Length=372 Score = 78.2 bits (191), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 70/242 (29%), Positives = 111/242 (46%), Gaps = 27/242 (11%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 R +++ +LT P +P F+ Y ++LG G F V + TG+ Sbjct 5 RFDCRSVSGLLTTTPQTPIKTEN-FNNFYTLTPKELGRGKFAVVR----QCISKSTGQEY 59 Query 928 AVKALKA-----DCGPQHRSGWKQEIDILRTLYH-EHIIKYKGCCEDQGEKSLQLVMEYV 981 A K+LK DC R+ EI +L H+I E+ E + LV+EY Sbjct 60 AAKSLKKRRRGQDC----RAEILHEIAVLELARSCPHVINLHEVYENATE--IILVLEYA 113 Query 982 PLGSLRDY-LPR--HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR--- 1035 G + + LP + ++ +QI EG+ YLH + +H DL +N+LL + Sbjct 114 AGGEIFNLCLPELAEMVSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLG 173 Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 +KI DFG+++ + E +RE +P + APE L A+D+W+ G+ Y LL Sbjct 174 DIKIVDFGMSRKIGNASE---LREIMGTPEYL-APEILNYDPITTATDMWNIGIIAYMLL 229 Query 1096 TH 1097 TH Sbjct 230 TH 231 Score = 43.1 bits (100), Expect = 0.013, Method: Compositional matrix adjust. Identities = 49/177 (28%), Positives = 76/177 (43%), Gaps = 27/177 (15%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 R RGQ+ R A +E A L S H+ +H V E I+V EY Sbjct 67 RRRGQDCR-------------AEILHEIAVLELARSCPHVINLHEVYENATEIILVLEYA 113 Query 691 EHGPL-DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 G + ++ L V + + +Q+ + YL N+VH ++ +NILL+ + Sbjct 114 AGGEIFNLCLPELAEMVSENDVIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSI---- 169 Query 750 GTSPF--IKLSDPGVG--LGALSREERVERIP-WLAPECLPGGANSLSTAMDKWGFG 801 P IK+ D G+ +G S + P +LAPE L + ++TA D W G Sbjct 170 --YPLGDIKIVDFGMSRKIGNASELREIMGTPEYLAPEIL--NYDPITTATDMWNIG 222 >sp|Q8VYA3|WAKLJ_ARATH Wall-associated receptor kinase-like 10 OS=Arabidopsis thaliana OX=3702 GN=WAKL10 PE=2 SV=1 Length=769 Score = 79.7 bits (195), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 69/221 (31%), Positives = 103/221 (47%), Gaps = 25/221 (11%) Query 891 VFHKRYLKK-------IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 VF+ R L+K R LGEG G+ ++Y + G +VAVK K Sbjct 420 VFNSRELEKATENFSLTRILGEG--GQGTVYKGMLVD---GRIVAVKKSKV-VDEDKLEE 473 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--- 1000 + E+ IL + H +I+K GCC + LV E++P G+L ++L S Sbjct 474 FINEVVILSQINHRNIVKLLGCCLETDVP--ILVYEFIPNGNLFEHLHDDSDDYTMTTWE 531 Query 1001 --LLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 L A I ++YLH+ HRD+ + N++LD K+ DFG ++ V H + Sbjct 532 VRLRIAVDIAGALSYLHSAASSPIYHRDIKSTNIMLDEKHRAKVSDFGTSRTVTVDHTHL 591 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 G V + PE + +F SDV+SFGV L EL+T Sbjct 592 TTVVSG--TVGYMDPEYFQSSQFTDKSDVYSFGVVLAELIT 630 Score = 44.3 bits (103), Expect = 0.007, Method: Compositional matrix adjust. Identities = 71/342 (21%), Positives = 133/342 (39%), Gaps = 77/342 (23%) Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 G S R N +L + +T++ LG+G + VY+G L ++ K+ DED Sbjct 413 GNVDSTRVFNSRELE-KATENFSLTRI--LGEGGQGTVYKGMLVDGRIVAVKKSKVVDED 469 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 L F ++SQ++H ++ + G C+ I+ Sbjct 470 KLEE-------------------------FINEVVILSQINHRNIVKLLGCCLETDVPIL 504 Query 686 VTEYVEHGPLDVWLRRERGHVPM-AW--KMVVAQQLASALSYLENKN---LVHGNVCGRN 739 V E++ +G L L + M W ++ +A +A ALSYL + + H ++ N Sbjct 505 VYEFIPNGNLFEHLHDDSDDYTMTTWEVRLRIAVDIAGALSYLHSAASSPIYHRDIKSTN 564 Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE----------RIPWLAPECLPGGAN 789 I+L A K+SD G SR V+ + ++ PE ++ Sbjct 565 IMLDEKHRA-------KVSDFGT-----SRTVTVDHTHLTTVVSGTVGYMDPEYFQ--SS 610 Query 790 SLSTAMDKWGFGATLLEICFDGEAPL------QSRSPSEKEHFYQRQHRLPE-------- 835 + D + FG L E+ GE + + R+ + +++RL + Sbjct 611 QFTDKSDVYSFGVVLAEL-ITGEKSVSFLRSQEYRTLATYFTLAMKENRLSDIIDARIRD 669 Query 836 ----PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 A + +CL + +RPS R + +L +++ ++ Sbjct 670 GCKLNQVTAAAKIARKCLNMKGRKRPSMRQVSMELEKIRSYS 711 >sp|O88764|DAPK3_RAT Death-associated protein kinase 3 OS=Rattus norvegicus OX=10116 GN=Dapk3 PE=1 SV=1 Length=448 Score = 79.0 bits (193), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 63/205 (31%), Positives = 99/205 (48%), Gaps = 20/205 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-----WKQEIDILRTLYH 956 +LG G F V C GTG A K +K P R G ++E+ ILR + H Sbjct 18 ELGSGQFAIVR-KC---QQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIRH 73 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLH 1015 +II E++ + + L++E V G L D+L + S+ + F +QI +G+ YLH Sbjct 74 PNIITLHDVFENKTD--VVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH 131 Query 1016 AQHYIHRDLAARNVLLDNDRL----VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 ++ H DL N++L + +K+ DFG+A + G E+ + +P F APE Sbjct 132 SKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNI---FGTPEF-VAPE 187 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 + +D+WS GV Y LL+ Sbjct 188 IVNYEPLGLEADMWSIGVITYILLS 212 Score = 37.7 bits (86), Expect = 0.60, Method: Compositional matrix adjust. Identities = 39/166 (23%), Positives = 71/166 (43%), Gaps = 10/166 (6%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S++ ++ H ++ +H V + +++ E V G L +L E+ + +Q+ Sbjct 66 SILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLA-EKESLTEDEATQFLKQIL 124 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIP 777 + YL +K + H ++ NI+L SP IKL D G+ + A S + + P Sbjct 125 DGVHYLHSKRIAHFDLKPENIMLLD---KHAASPRIKLIDFGIAHRIEAGSEFKNIFGTP 181 Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 ++APE + L D W G + I G +P + E Sbjct 182 EFVAPEIV--NYEPLGLEADMWSIG-VITYILLSGASPFLGETKQE 224 >sp|Q9TTK0|CDKL2_RABIT Cyclin-dependent kinase-like 2 OS=Oryctolagus cuniculus OX=9986 GN=CDKL2 PE=2 SV=1 Length=566 Score = 79.3 bits (194), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 63/199 (32%), Positives = 102/199 (51%), Gaps = 18/199 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG +G V + C N +G +VA+K L++D + +EI +L+ L HE+++ Sbjct 10 VGEGSYGMV-MKC---RNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL----AQLLLFAQQICEGMAYLHAQ 1017 C+ + K LV E+V ++ D L GL Q LF QI G+ + H+ Sbjct 66 LLEVCKKK--KRWYLVFEFVD-HTILDDLELFPNGLDDQVVQKYLF--QIINGIGFCHSH 120 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEY 1076 + IHRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L + Sbjct 121 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDV 177 Query 1077 KFYYASDVWSFGVTLYELL 1095 K+ A DVW+ G + E+L Sbjct 178 KYGKAVDVWAIGCLVTEML 196 Score = 41.6 bits (96), Expect = 0.046, Method: Compositional matrix adjust. Identities = 56/236 (24%), Positives = 96/236 (41%), Gaps = 52/236 (22%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ---- 716 L+ Q+ H +L + VC + +V E+V+H LD + P V Q Sbjct 54 LLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILD-----DLELFPNGLDDQVVQKYLF 108 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVER 775 Q+ + + + + N++H ++ NIL+++ G+ +KL D G A E + Sbjct 109 QIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFARTLAAPGEVYTDY 161 Query 776 IP---WLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGEAPLQ----------S 817 + + APE L G A+D W G + E+ F G++ + + Sbjct 162 VATRWYRAPELLVGDV-KYGKAVDVWAIGCLVTEMLMGEPLFPGDSDIDQLYLIMRCLGN 220 Query 818 RSPSEKEHFYQR----QHRLPEPS--------CPQLA----TLTSQCLTYEPTQRP 857 P +E FY+ RLPE P+L+ L +CL +P +RP Sbjct 221 LIPRHQELFYKNPVFAGVRLPEIKESEPLERRYPKLSEVVIDLAKKCLHVDPDKRP 276 >sp|Q55DD4|PAKD_DICDI Serine/threonine-protein kinase pakD OS=Dictyostelium discoideum OX=44689 GN=pakD PE=3 SV=1 Length=1678 Score = 80.1 bits (196), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 66/224 (29%), Positives = 101/224 (45%), Gaps = 41/224 (18%) Query 897 LKKIRDL-GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 L K+R++ G G GKV Y N TGE VA+K +K D EI ++ Sbjct 1375 LYKVREVVGGGSTGKV----YVGENSITGEKVAIKKMKVDNNNIKNII--NEISTMKNSK 1428 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL------------------ 997 H+++IKY + L+MEY+ GSL D L + I + Sbjct 1429 HKNVIKY--VSSHLVINHIWLIMEYMSYGSLTD-LISNCINIQCNGNNQQQQQQQQQQQT 1485 Query 998 ----AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + + QQ+ +GM Y+H H HRD+ + N+LL D VKI DFG + Sbjct 1486 YFIESHIAYICQQVLQGMDYIHKGHRTHRDIKSDNILLGKDGSVKIADFGFVANLT---- 1541 Query 1054 YYRVREDGDSPV---FWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 R + +S V ++ APE ++ ++ + D+WS G+ EL Sbjct 1542 --RKKLQRNSVVGTPYFMAPELIRGNQYNHKVDIWSLGILAREL 1583 Score = 34.3 bits (77), Expect = 9.4, Method: Compositional matrix adjust. Identities = 37/160 (23%), Positives = 65/160 (41%), Gaps = 20/160 (13%) Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSR 769 + QQ+ + Y+ + H ++ NILL + G +K++D G + L R Sbjct 1495 ICQQVLQGMDYIHKGHRTHRDIKSDNILLGKDG-------SVKIADFGFVANLTRKKLQR 1547 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 V ++APE + G N + +D W G E+ +GE P ++ P + F Sbjct 1548 NSVVGTPYFMAPELIRG--NQYNHKVDIWSLGILARELS-EGEPPY-AKYPPVRALFLLT 1603 Query 830 QHRLPEPSCPQ-----LATLTSQCLTYEPTQRPSFRTILR 864 +P+ P + CL + +RP +LR Sbjct 1604 LEGVPDFKEPNKWSSDFIEFVNLCLNLDDKRRPDAHYLLR 1643 >sp|P12965|MOS_XENLA Serine/threonine-protein kinase mos OS=Xenopus laevis OX=8355 GN=mos PE=2 SV=1 Length=359 Score = 77.8 bits (190), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 80/306 (26%), Positives = 127/306 (42%), Gaps = 50/306 (16%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHE 957 + LG G FG V Y GE VA+K +K R + E++ R L H Sbjct 66 LEPLGSGGFGSVYRATY------RGETVALKKVKRSTKNSLASRQSFWAELNAAR-LRHP 118 Query 958 HIIKY----KGCCEDQGEKSLQLVMEYVPLGSL--RDYLPRHSIGLAQLLLFAQQICEGM 1011 H+++ C D G ++MEY G+L R Y +G + +A+ + +G+ Sbjct 119 HVVRVVAASASCPGDPGCPG-TIIMEYTGTGTLHQRIYGRSPPLGAEICMRYARHVADGL 177 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-------YRVREDGDSP 1064 +LH +H DL NVLL L KIGDFG ++ + EG E ++R G + Sbjct 178 RFLHRDGVVHLDLKPANVLLAPGDLCKIGDFGCSQRLREGDEAAGGEPCCTQLRHVGGT- 236 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 APE LK +D++SF +TL++++ ++ L G Q + + Sbjct 237 YTHRAPELLKGEPVTAKADIYSFAITLWQMV----------SRELPYTGDRQCVLYAVVA 286 Query 1125 TELLERGERLPRPDKCPC--------EVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 +L RP+ P ++++CW RP E L+ L+ Sbjct 287 YDL--------RPEMGPLFSHTEEGRAARTIVQSCWAARPQERPNAEQLLERLEQECAMC 338 Query 1177 QGQAPS 1182 G PS Sbjct 339 TGGPPS 344 >sp|O22932|CIPKB_ARATH CBL-interacting serine/threonine-protein kinase 11 OS=Arabidopsis thaliana OX=3702 GN=CIPK11 PE=1 SV=1 Length=435 Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 70/231 (30%), Positives = 112/231 (48%), Gaps = 28/231 (12%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL---KA 934 + + S ++ +F K L K+ LG G F KV + + TG+ VAVK L K Sbjct 4 IEIAAGSGDNNDALFGKYELGKL--LGCGAFAKV----FHARDRRTGQSVAVKILNKKKL 57 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994 P + K+EI I+R L H +I+K + + + ME+V G L + + +H Sbjct 58 LTNPALANNIKREISIMRRLSHPNIVKLHEVMATKSK--IFFAMEFVKGGELFNKISKHG 115 Query 995 IGLAQLL--LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 L++ L + QQ+ + Y HA+ HRDL N+L+D + +K+ DFGL+ + Sbjct 116 -RLSEDLSRRYFQQLISAVGYCHARGVYHRDLKPENLLIDENGNLKVSDFGLSALTDQ-- 172 Query 1053 EYYRVREDG------DSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELLT 1096 +R DG +P + APE L + + A DVWS G+ L+ L+ Sbjct 173 ----IRPDGLLHTLCGTPA-YVAPEILSKKGYEGAKVDVWSCGIVLFVLVA 218 Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 58/248 (23%), Positives = 101/248 (41%), Gaps = 25/248 (10%) Query 631 RDRGQELRVVLKVLDP----SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 RDR V +K+L+ ++ +A S+M ++SH ++ +H V + Sbjct 39 RDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHPNIVKLHEVMATKSKIFFA 98 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 E+V+ G L + + G + QQL SA+ Y + + H ++ N+L+ G Sbjct 99 MEFVKGGELFNKISKH-GRLSEDLSRRYFQQLISAVGYCHARGVYHRDLKPENLLIDENG 157 Query 747 LAEGTSPFIKLSDPGVGLGALSREERVERI--------PWLAPECLPGGANSLSTAMDKW 798 +K+SD GL AL+ + R + + ++APE L +D W Sbjct 158 -------NLKVSD--FGLSALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYE-GAKVDVW 207 Query 799 GFGATLLEICFDGEAPLQS-RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857 G L + G P + + Y+ ++R P P L S+ L P R Sbjct 208 SCGIVLF-VLVAGYLPFNDPNVMNMYKKIYKGEYRFPRWMSPDLKRFVSRLLDINPETRI 266 Query 858 SFRTILRD 865 + IL+D Sbjct 267 TIDEILKD 274 >sp|Q8C0V7|SMKW_MOUSE Putative sperm motility kinase W OS=Mus musculus OX=10090 GN=Stk-ps2 PE=5 SV=2 Length=499 Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 69/207 (33%), Positives = 98/207 (47%), Gaps = 26/207 (13%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 K + LG G FG V L C+ T +VA+K + + ++ G + EI L L H Sbjct 15 KVLFTLGHGSFGTVKLACHLKTK----ALVAIKMV--ELSKKNIRGIRAEIATLEKLQHP 68 Query 958 HIIKYKGCCEDQ---GEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEG 1010 +II C Q K + +V EY+P G+L D + P H ++ Q+ Sbjct 69 NII-----CLFQVLVTSKHINIVTEYIPGGNLFDIIKEDGPMHEEEARRIF---GQVVSA 120 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 + Y H Q +H+D+ A+N+L D + VKI DFGLA G R+ G F AP Sbjct 121 VKYCHNQDIVHQDIKAQNILRDEEGNVKIIDFGLAIRCRSG--TLLKRQCGTKSCF--AP 176 Query 1071 E-CLKEYKFYYASDVWSFGVTLYELLT 1096 E L+E +DVWS GV LY + T Sbjct 177 ELVLQEPYDGKKADVWSLGVLLYFITT 203 Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 60/231 (26%), Positives = 98/231 (42%), Gaps = 17/231 (7%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K+++ S +I E A+L ++ H ++ + V V +VTEY+ G L Sbjct 40 VAIKMVELSKKNIRGIRAEIATL-EKLQHPNIICLFQVLVTSKHINIVTEYIPGGNL-FD 97 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + +E G + + Q+ SA+ Y N+++VH ++ +NIL G +K+ Sbjct 98 IIKEDGPMHEEEARRIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEG-------NVKII 150 Query 759 DPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 D G+ + G L + + + APE + A D W G LL G P Sbjct 151 DFGLAIRCRSGTLLKRQCGTK-SCFAPELVLQEPYDGKKA-DVWSLG-VLLYFITTGYYP 207 Query 815 LQSRSPSE-KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + + E +E + +P QL L Q LT P RPS I R Sbjct 208 FRGSTMKEMEEKIATGTYDIPTHVSGQLENLIHQILTVPPEMRPSIEDIER 258 >sp|P06493|CDK1_HUMAN Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3 Length=297 Score = 77.0 bits (188), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 62/234 (26%), Positives = 113/234 (48%), Gaps = 25/234 (11%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957 KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L H Sbjct 6 KIEKIGEGTYGVV----YKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAY 1013 +I+ + + L L+ E++ + L+ YL P + + + + QI +G+ + Sbjct 62 NIVSLQDVL--MQDSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWYAPE 1071 H++ +HRDL +N+L+D+ +K+ DFGLA+A +P RV +++ +PE Sbjct 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP-----IRVYTHEVVTLWYRSPE 173 Query 1072 C-LKEYKFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQM 1119 L ++ D+WS G EL T H DS + +G ++ Sbjct 174 VLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV 227 >sp|Q8S8Y9|WNK2_ARATH Serine/threonine-protein kinase WNK2 OS=Arabidopsis thaliana OX=3702 GN=WNK2 PE=1 SV=1 Length=568 Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 56/164 (34%), Positives = 90/164 (55%), Gaps = 10/164 (6%) Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SI 995 P+ + +EI +L+TL H++I+K+ D S+ V E G+LR Y RH + Sbjct 63 NPEELEKFFREIHLLKTLNHQNIMKFYTSWVDTNNLSINFVTELFTSGTLRQYRLRHRRV 122 Query 996 GLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFGLAKAVPEGH 1052 + + + +QI +G+ YLH++ IHRDL N+ ++ N VKIGD GLA + + H Sbjct 123 NIRAVKQWCKQILKGLLYLHSRSPPIIHRDLKCDNIFINGNQGEVKIGDLGLAAILRKSH 182 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 VR G +P F APE E ++ DV++FG+ + E++T Sbjct 183 A---VRCVG-TPEF-MAPEVYDE-EYNELVDVYAFGMCVLEMVT 220 >sp|P48734|CDK1_BOVIN Cyclin-dependent kinase 1 OS=Bos taurus OX=9913 GN=CDK1 PE=2 SV=2 Length=297 Score = 77.0 bits (188), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 61/215 (28%), Positives = 108/215 (50%), Gaps = 25/215 (12%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957 KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L H Sbjct 6 KIEKIGEGTYGVV----YKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAY 1013 +I+ + + L L+ E++ + L+ YL P + + + + QI +G+ + Sbjct 62 NIVSLQDVL--MQDSRLYLIFEFLSM-DLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVF 118 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWYAPE 1071 H++ +HRDL +N+L+D+ +K+ DFGLA+A +P RV +++ +PE Sbjct 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP-----IRVYTHEVVTLWYRSPE 173 Query 1072 C-LKEYKFYYASDVWSFGVTLYELLT-----HCDS 1100 L ++ D+WS G EL T H DS Sbjct 174 VLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDS 208 >sp|Q12469|SKM1_YEAST Serine/threonine-protein kinase SKM1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SKM1 PE=1 SV=1 Length=655 Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 53/184 (29%), Positives = 89/184 (48%), Gaps = 17/184 (9%) Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY-KGCCEDQGEKSLQLVMEYV 981 GE VA+K ++ P+ + E+ ++ E+I+ + + D E L ++MEY+ Sbjct 399 VGERVAIKQIRLSEQPK-KQLIMNELLVMNDSRQENIVNFLEAYIIDDEE--LWVIMEYM 455 Query 982 PLGSLRDYLP--------RHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031 G L D L HS + Q+ ++ C+G+ +LH + IHRD+ + N+LL Sbjct 456 EGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQGLKFLHNKKIIHRDIKSDNILL 515 Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091 ++ LVKI DFG + E R +W APE + + + DVWS G+ L Sbjct 516 NSQGLVKITDFGFCVELTEKRSK---RATMVGTPYWMAPEIVNQKGYDEKVDVWSLGIML 572 Query 1092 YELL 1095 E++ Sbjct 573 IEMI 576 Score = 52.0 bits (123), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 51/212 (24%), Positives = 84/212 (40%), Gaps = 30/212 (14%) Query 670 LAFVHGVCVRGPENIMVTEYVEHG----PLDVWLRRERGH--VPMAWKMV--VAQQLASA 721 + F+ + E ++ EY+E G LD R G P+ + + ++ Sbjct 435 VNFLEAYIIDDEELWVIMEYMEGGCLTDILDAVARSNTGEHSSPLNENQMAYIVKETCQG 494 Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---- 777 L +L NK ++H ++ NILL GL +K++D G + E+R +R Sbjct 495 LKFLHNKKIIHRDIKSDNILLNSQGL-------VKITDFGFCVELT--EKRSKRATMVGT 545 Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR----QH 831 W+APE + +D W G L+E+ +GE P + P + + + Sbjct 546 PYWMAPEIV--NQKGYDEKVDVWSLGIMLIEM-IEGEPPYLNEDPLKALYLIANNGSPKL 602 Query 832 RLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 R PE Q CL R S R +L Sbjct 603 RHPESVSKQTKQFLDACLQVNVESRASVRKLL 634 >sp|Q93ZS4|NIK3_ARATH Protein NSP-INTERACTING KINASE 3 OS=Arabidopsis thaliana OX=3702 GN=NIK3 PE=1 SV=1 Length=632 Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 67/203 (33%), Positives = 97/203 (48%), Gaps = 19/203 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG-PQHRSGWKQEIDILRTLYHEHIIK 961 LG G +G V NDGT +VAVK LK DC ++ E++ + H ++++ Sbjct 307 LGRGGYGIV---YKGHLNDGT--LVAVKRLK-DCNIAGGEVQFQTEVETISLALHRNLLR 360 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHA 1016 +G C E+ L V Y+P GS+ L + ++ ++ A G+ YLH Sbjct 361 LRGFCSSNQERIL--VYPYMPNGSVASRLKDNIRGEPALDWSRRKKIAVGTARGLVYLHE 418 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 Q IHRD+ A N+LLD D +GDFGLAK + H V V APE L Sbjct 419 QCDPKIIHRDVKAANILLDEDFEAVVGDFGLAKLLD--HRDSHVTTAVRGTVGHIAPEYL 476 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 + +DV+ FG+ L EL+T Sbjct 477 STGQSSEKTDVFGFGILLLELIT 499 >sp|Q9FJ54|CIPKK_ARATH CBL-interacting serine/threonine-protein kinase 20 OS=Arabidopsis thaliana OX=3702 GN=CIPK20 PE=1 SV=1 Length=439 Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 63/201 (31%), Positives = 96/201 (48%), Gaps = 14/201 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYH 956 R LG+G F KV Y N TGE VA+K + D + G K+EI ++R + H Sbjct 16 RLLGQGTFAKV----YHARNIKTGESVAIKVI--DKQKVAKVGLIDQIKREISVMRLVRH 69 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016 H++ + + + MEYV G L D + + + + QQ+ + Y H+ Sbjct 70 PHVVFLHEVMASKTK--IYFAMEYVKGGELFDKVSKGKLKENIARKYFQQLIGAIDYCHS 127 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + HRDL N+LLD + +KI DFGL+ + + +P + APE + + Sbjct 128 RGVYHRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPAY-VAPEVIGKK 186 Query 1077 KFYYA-SDVWSFGVTLYELLT 1096 + A +DVWS GV LY LL Sbjct 187 GYDGAKADVWSCGVVLYVLLA 207 Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 65/280 (23%), Positives = 107/280 (38%), Gaps = 43/280 (15%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LGQGT VY R G E + D+ + +V L +D +I Sbjct 18 LGQGTFAKVYHARNIKTG-----------ESVAIKVIDKQKVAKVGL--IDQIKREI--- 61 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 S+M V H H+ F+H V + EYV+ G L + + +G + Sbjct 62 -----SVMRLVRHPHVVFLHEVMASKTKIYFAMEYVKGGEL--FDKVSKGKLKENIARKY 114 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 QQL A+ Y ++ + H ++ N+LL G +K+SD GL AL ++ + Sbjct 115 FQQLIGAIDYCHSRGVYHRDLKPENLLLDENGD-------LKISD--FGLSALRESKQQD 165 Query 775 RI--------PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EH 825 + ++APE + G D W G L + G P ++ E Sbjct 166 GLLHTTCGTPAYVAPEVI-GKKGYDGAKADVWSCGVVLY-VLLAGFLPFHEQNLVEMYRK 223 Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + + + P P++ L S+ L P R I+ + Sbjct 224 ITKGEFKCPNWFPPEVKKLLSRILDPNPNSRIKIEKIMEN 263 >sp|Q7Y0B9|SAPK8_ORYSJ Serine/threonine-protein kinase SAPK8 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK8 PE=1 SV=1 Length=371 Score = 77.8 bits (190), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 78/238 (33%), Positives = 115/238 (48%), Gaps = 25/238 (11%) Query 885 PASDPTVFHK--RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 P D + H RY + +RD+G G+FG L + T E+VAVK ++ G + Sbjct 20 PGMDMPIMHDSDRY-ELVRDIGSGNFGVARLM----RDRRTMELVAVKYIER--GEKIDD 72 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLL 1001 ++EI R+L H +II++K L +VMEY G L + + ++ + Sbjct 73 NVQREIINHRSLKHPNIIRFKEVI--LTPTHLAIVMEYASGGELFERICKNVRFSEDEAR 130 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVR 1058 F QQ+ G++Y H+ HRDL N LLD RL KI DFG +K+ + + + Sbjct 131 YFFQQLISGVSYCHSMQVCHRDLKLENTLLDGSPAPRL-KICDFGYSKS---SVLHSQPK 186 Query 1059 EDGDSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLELI 1112 +P + APE L KEY A DVWS GVTLY ++ + P P F + I Sbjct 187 STVGTPA-YIAPEVLLKKEYDGKTA-DVWSCGVTLYVMVVGAYPFEDPEEPKNFRKTI 242 Score = 34.3 bits (77), Expect = 6.9, Method: Compositional matrix adjust. Identities = 35/138 (25%), Positives = 59/138 (43%), Gaps = 14/138 (10%) Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER 775 QQL S +SY + VC R++ L L +P +K+ D G ++ + Sbjct 134 QQLISGVSYCHSM-----QVCHRDLKLENTLLDGSPAPRLKICDFGYSKSSVLHSQPKST 188 Query 776 I---PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832 + ++APE L TA D W G TL + G P + P E ++F + R Sbjct 189 VGTPAYIAPEVLLKKEYDGKTA-DVWSCGVTLY-VMVVGAYPFE--DPEEPKNFRKTIQR 244 Query 833 L--PEPSCPQLATLTSQC 848 + + S P+ ++ +C Sbjct 245 ILNVQYSIPENVDISPEC 262 >sp|P93101|CDC2_OXYRB Cell division control protein 2 homolog OS=Oxybasis rubra OX=3560 GN=CDC2 PE=2 SV=1 Length=294 Score = 76.6 bits (187), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 63/208 (30%), Positives = 100/208 (48%), Gaps = 20/208 (10%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYH 956 +K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ + H Sbjct 5 EKVEKIGEGTYGVV----YKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQH 60 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR--DYLPRHSIGLAQLLLFAQQICEGMAYL 1014 +I++ + EK L LV EY+ L + D P + + F QI G+AY Sbjct 61 GNIVRLQDVV--HSEKRLYLVFEYLDLDLKKHMDSCPDFAKDPRMIKRFLYQILRGIAYC 118 Query 1015 HAQHYIHRDLAARNVLLD-NDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWY-AP 1070 H+ +HRDL +N+L+D +K+ DFGLA+A +P + V WY AP Sbjct 119 HSHRVLHRDLKPQNLLIDRQTNALKLADFGLARAFGIPVRTFTHEV------VTLWYRAP 172 Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTH 1097 E L + Y DVWS G E++ Sbjct 173 EILLGSRHYSTPVDVWSVGCIFAEMVNQ 200 >sp|P35567|CDK1A_XENLA Cyclin-dependent kinase 1-A OS=Xenopus laevis OX=8355 GN=cdk1-a PE=1 SV=1 Length=302 Score = 77.0 bits (188), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 66/235 (28%), Positives = 113/235 (48%), Gaps = 27/235 (11%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957 KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L H Sbjct 6 KIEKIGEGTYGVV----YKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHP 61 Query 958 HIIKYKGCCED--QGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLL--FAQQICEGM 1011 +I+ C D + L L+ E++ + L+ YL G + +L+ + QI +G+ Sbjct 62 NIV----CLLDVLMQDSRLYLIFEFLSM-DLKKYLDSIPSGQYIDTMLVKSYLYQILQGI 116 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-AP 1070 + H++ +HRDL +N+L+D+ ++K+ DFGLA+A Y + WY AP Sbjct 117 VFCHSRRVLHRDLKPQNLLIDSKGVIKLADFGLARAFGIPVRVYT----HEVVTLWYRAP 172 Query 1071 EC-LKEYKFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQM 1119 E L ++ DVWS G E+ T H DS + +G ++ Sbjct 173 EVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEV 227 >sp|Q55CL6|MP2K1_DICDI Dual specificity mitogen-activated protein kinase kinase 1 OS=Dictyostelium discoideum OX=44689 GN=mekA PE=1 SV=1 Length=660 Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 60/200 (30%), Positives = 100/200 (50%), Gaps = 13/200 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 LK IR LG G G V L ++ + G +A+K + D R E+ L + Sbjct 292 LKIIRVLGRGAGGVVKLAYHETS----GTYIALKVITLDIQENIRKQIILELKTLHKTSY 347 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLH 1015 +I+ + +G S+ + +E++ LGSL D + + S I L A Q+ +G+ YLH Sbjct 348 PYIVSFYDAFYTEG--SIFIALEFMELGSLSDIMKKTSTIPEPVLGKIAFQVLQGLVYLH 405 Query 1016 AQ-HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR-VREDGDSPVFWYAPECL 1073 + H IHRD+ N+L++N KI DFG++ + H + V G V + +PE + Sbjct 406 RKLHLIHRDIKPSNILVNNKGEAKIADFGVSGQLQ--HTLSKAVTWVG--TVTYMSPERI 461 Query 1074 KEYKFYYASDVWSFGVTLYE 1093 + + S++WS G+T+ E Sbjct 462 SGRSYSFDSEIWSLGLTILE 481 >sp|X5M8U1|GCY17_CAEEL Receptor-type guanylate cyclase gcy-17 OS=Caenorhabditis elegans OX=6239 GN=gcy-17 PE=2 SV=1 Length=1088 Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 70/274 (26%), Positives = 133/274 (49%), Gaps = 27/274 (10%) Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972 Y Y N+ E+VA A K D PQ + E+ +R+L H+++ K+ G C + + Sbjct 564 FYIYQVRNN---EVVA--ANKHDFRPQLTDVERSELRQMRSLDHDNLNKFIGLCLNS--Q 616 Query 973 SLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA--QQICEGMAYLHAQH-YIHRDLAARNV 1029 L + Y GSL D + R S+ + + + + I G+ ++H + H L++R+ Sbjct 617 QLLSIWRYCSRGSLADVISRSSMQMDSFFMLSLIRDIANGLGFIHTSMLHFHGYLSSRSC 676 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFYYASDVWSFG 1088 L+D+ VKI DFGL +E + + + W+APE L+ + +D++SFG Sbjct 677 LIDDRWQVKISDFGL-------NEVRGMDKLSTENMLWWAPEVLRGLEQRSKEADIYSFG 729 Query 1089 VTLYELLTHCDSS--QSPPTKFLELI-GIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 + E++T + ++ K E+I + +G +R + L + + P V Sbjct 730 IICSEVITRSSAFDLENRKEKPEEIIYQLKKGGFNAIRPSLLTDEALEIN-----PALV- 783 Query 1146 HLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 HL+++CW + S RP + + +L+ +++ +G Sbjct 784 HLIRDCWTEKPSERPPIDQVRSLLRGMNDGKKGN 817 Score = 50.4 bits (119), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 57/236 (24%), Positives = 95/236 (40%), Gaps = 33/236 (14%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA 721 M + H +L G+C+ + + + Y G L + R + + + + + +A+ Sbjct 597 MRSLDHDNLNKFIGLCLNSQQLLSIWRYCSRGSLADVISRSSMQMDSFFMLSLIRDIANG 656 Query 722 LSYLENKNL-VHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREERVERI 776 L ++ L HG + R+ L+ +K+SD G+ G+ LS E + Sbjct 657 LGFIHTSMLHFHGYLSSRSCLI-------DDRWQVKISDFGLNEVRGMDKLS----TENM 705 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA-PLQSRSPSEKEHFYQRQH---R 832 W APE L G S D + FG E+ A L++R +E YQ + Sbjct 706 LWWAPEVLRG-LEQRSKEADIYSFGIICSEVITRSSAFDLENRKEKPEEIIYQLKKGGFN 764 Query 833 LPEPSC---------PQLATLTSQCLTYEPTQRP---SFRTILRDLTRLQPHNLAD 876 PS P L L C T +P++RP R++LR + + NL D Sbjct 765 AIRPSLLTDEALEINPALVHLIRDCWTEKPSERPPIDQVRSLLRGMNDGKKGNLMD 820 >sp|Q5WA76|PUB70_ORYSJ U-box domain-containing protein 70 OS=Oryza sativa subsp. japonica OX=39947 GN=PUB70 PE=1 SV=1 Length=805 Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 61/205 (30%), Positives = 98/205 (48%), Gaps = 23/205 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG V VA+K L+ D Q +S ++QE+ IL + H H++ Sbjct 451 IGEGGFGCVYKGIL------RNMTVAIKVLRPD-SLQGQSQFEQEVSILSRVRHPHLVTL 503 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 G C + S LV E++P GSL D+L R ++ + +IC + +LH Sbjct 504 LGACSE----SSTLVYEFLPNGSLEDFLMCSDKRQTLTWQARIRIIAEICSALIFLHKNK 559 Query 1019 ---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH----EYYRVREDGDSPVFWYAPE 1071 +H DL N+LL + + K+ DFG+++ + + YR +P++ PE Sbjct 560 PHPVVHGDLKPANILLGVNLVSKLSDFGISRLLIQSSTNNTTLYRTMHPVGTPLYM-DPE 618 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 L + SDV+SFG+ + LLT Sbjct 619 FLSTGELTPQSDVYSFGIVVLRLLT 643 Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 49/196 (25%), Positives = 88/196 (45%), Gaps = 27/196 (14%) Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 + + V +KVL P F + S++S+V H HL + G C + +V E++ +G Sbjct 465 RNMTVAIKVLRPDSLQGQSQFEQEVSILSRVRHPHLVTLLGAC--SESSTLVYEFLPNGS 522 Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAE 749 L+ +L + W ++ + ++ SAL +L +VHG++ NILL Sbjct 523 LEDFLMCSDKRQTLTWQARIRIIAEICSALIFLHKNKPHPVVHGDLKPANILL------- 575 Query 750 GTSPFIKLSDPGVG---LGALSREERVERIP-------WLAPECLPGGANSLSTAMDKWG 799 G + KLSD G+ + + + + R ++ PE L G L+ D + Sbjct 576 GVNLVSKLSDFGISRLLIQSSTNNTTLYRTMHPVGTPLYMDPEFLSTG--ELTPQSDVYS 633 Query 800 FGATLLEICFDGEAPL 815 FG +L + G+ P+ Sbjct 634 FGIVVLRL-LTGKPPV 648 >sp|P23572|CDK1_DROME Cyclin-dependent kinase 1 OS=Drosophila melanogaster OX=7227 GN=Cdk1 PE=1 SV=1 Length=297 Score = 76.6 bits (187), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 63/208 (30%), Positives = 100/208 (48%), Gaps = 20/208 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLY 955 +KI +GEG +G V Y N TG++VA+K ++ + + S +EI +L+ L Sbjct 4 FEKIEKIGEGTYGVV----YKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELK 59 Query 956 HEHIIKYKGCCED--QGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLL-FAQQICEG 1010 HE+I+ C ED E + L+ E++ L D LP ++L+ + QI Sbjct 60 HENIV----CLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSA 115 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-A 1069 + + H + +HRDL +N+L+D L+K+ DFGL ++ Y + WY A Sbjct 116 ILFCHRRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYT----HEIVTLWYRA 171 Query 1070 PECLKEYKFYYA-SDVWSFGVTLYELLT 1096 PE L Y D+WS G E+ T Sbjct 172 PEVLLGSPRYSCPVDIWSIGCIFAEMAT 199 Score = 37.0 bits (84), Expect = 1.0, Method: Compositional matrix adjust. Identities = 64/317 (20%), Positives = 125/317 (39%), Gaps = 76/317 (24%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGS-GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ ++ +G+GT VY+GR R+ G ++ +++ +D VP Sbjct 2 EDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVP---------------- 45 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + A E SL+ ++ H ++ + V + ++ E+ L + L++ Sbjct 46 ------STAIREI-SLLKELKHENIVCLEDVLMEENRIYLIFEF-----LSMDLKKYMDS 93 Query 706 VPMAWKM------VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 +P+ M Q+ SA+ + + ++H ++ +N+L+ + GL IK++D Sbjct 94 LPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSGL-------IKVAD 146 Query 760 PGVG--LGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC-----FD 810 G+G G R + + + APE L G S +D W G E+ F Sbjct 147 FGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPR-YSCPVDIWSIGCIFAEMATRKPLFQ 205 Query 811 GEAPLQS--------RSPSEK-----EHFYQRQHRLPEPSCPQLAT-----------LTS 846 G++ + ++P+E ++ P S QL L Sbjct 206 GDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDANGIDLIQ 265 Query 847 QCLTYEPTQRPSFRTIL 863 + L Y+P R S + IL Sbjct 266 KMLIYDPVHRISAKDIL 282 >sp|Q8SRU0|CSK2A_ENCCU Probable casein kinase II subunit alpha homolog OS=Encephalitozoon cuniculi (strain GB-M1) OX=284813 GN=CKA1 PE=3 SV=1 Length=319 Score = 77.0 bits (188), Expect = 1e-13, Method: Composition-based stats. Identities = 54/177 (31%), Positives = 93/177 (53%), Gaps = 20/177 (11%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 E + +KALK P ++ +E+ ILR L H++IIK D + L+ EY+ Sbjct 59 EKIVIKALK----PVRKAKICREVLILRNLSHKNIIKLMDVVVDPESQIYSLIFEYI--- 111 Query 985 SLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL-VKIGDF 1042 DY + ++ +++QI ++Y H+ IHRD+ +N++++ R +KI D+ Sbjct 112 EHEDYAKIFEKLCYKDIVEYSRQILSALSYCHSMGIIHRDIKPQNMVINQARRELKIIDW 171 Query 1043 GLAKAVPEGHEYYRVREDGDSPV---FWYAPECLKEYKFY-YASDVWSFGVTLYELL 1095 GLA E+Y +++ V ++ PE L +Y +Y Y+ D+WSFG L EL+ Sbjct 172 GLA-------EFYHPKKEYSVRVASRYYKGPELLVDYPYYDYSLDIWSFGCVLAELV 221 >sp|Q5N942|SAPK4_ORYSJ Serine/threonine-protein kinase SAPK4 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK4 PE=2 SV=2 Length=360 Score = 77.8 bits (190), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 73/203 (36%), Positives = 100/203 (49%), Gaps = 20/203 (10%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +RD+G G+FG L N T E+VAVK ++ G + +EI R+L H +I Sbjct 7 VRDIGSGNFGVARLM----RNRETRELVAVKCIER--GHRIDENVYREIINHRSLRHPNI 60 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I++K L +VME+ G L D + R + F QQ+ G++Y H Sbjct 61 IRFKEVI--LTPTHLMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVSYCHHMQ 118 Query 1019 YIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-- 1073 HRDL NVLLD RL KI DFG +K+ + R + +P + APE L Sbjct 119 ICHRDLKLENVLLDGSPAPRL-KICDFGYSKS---SVLHSRPKSAVGTPAY-IAPEVLSR 173 Query 1074 KEYKFYYASDVWSFGVTLYELLT 1096 +EY A DVWS GVTLY +L Sbjct 174 REYDGKLA-DVWSCGVTLYVMLV 195 >sp|P28582|CDPK_DAUCA Calcium-dependent protein kinase OS=Daucus carota OX=4039 PE=2 SV=2 Length=532 Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 64/209 (31%), Positives = 102/209 (49%), Gaps = 30/209 (14%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHE- 957 ++LG G FG V Y T + +G++ A K++ + + K+EI IL+ L + Sbjct 85 KELGRGQFGCV----YQCTENSSGQLYACKSILKRKLVSKNDKEDIKREIQILQHLSGQP 140 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-------YLPRHSIGLAQLLLFAQQICEG 1010 +I+++KG ED+ +S+ LVME G L D Y R + + + ++ +C Sbjct 141 NIVEFKGVFEDR--QSVHLVMELCAGGELFDRIIAQGHYSERAAATICRQIVNVVHVC-- 196 Query 1011 MAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 H +HRDL N LL D D ++K DFGL+ + EG Y + ++ Sbjct 197 ----HFMGVMHRDLKPENFLLSSKDKDAMLKATDFGLSVFIEEGKVYRNIV----GSAYY 248 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLT 1096 APE L+ + D+WS GV LY LL+ Sbjct 249 VAPEVLRR-SYGKEIDIWSAGVILYILLS 276 >sp|Q03002|FRK1_YEAST Fatty acyl-CoA synthetase and RNA processing-associated kinase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=FRK1 PE=1 SV=1 Length=865 Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 66/206 (32%), Positives = 104/206 (50%), Gaps = 19/206 (9%) Query 903 LGEGHFGKVSL---YCYDPTNDGTGEM---VAVKALKADC-GPQHRSGWK--QEIDILRT 953 LGEG FGKV L + +++ T + VA+K +K D +R K +EI+ L+ Sbjct 47 LGEGEFGKVKLGWPKNFSNSSNSTFDFPKQVAIKLIKRDSISNDYRKEVKIYREINALKH 106 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGM 1011 L H +I+K + Q + + +V+EY G Y+ R + LF+Q I G+ Sbjct 107 LSHPNIVKLEEVL--QNSRYIGIVLEYACGGEFYKYIQKKRRLKEMNACRLFSQLIS-GV 163 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 Y+H++ +HRDL N+LLD + + I DFG +E ++ SP + APE Sbjct 164 HYIHSKGLVHRDLKLENLLLDKNENLVITDFGFVNEFCSRNEL--MKTSCGSPCYA-APE 220 Query 1072 CLKEYKFYYA--SDVWSFGVTLYELL 1095 + + Y A +D+WS GV LY +L Sbjct 221 LVISAEPYEARKADIWSCGVILYAIL 246 >sp|Q6FN53|STE20_CANGA Serine/threonine-protein kinase STE20 OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=STE20 PE=3 SV=1 Length=915 Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 55/200 (28%), Positives = 100/200 (50%), Gaps = 13/200 (7%) Query 899 KIRDL---GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 K RDL G+G G V + + D VA+K + + P+ + EI ++R Sbjct 619 KYRDLIKIGQGASGGVYIAHDTESEDS----VAIKQMNLEKQPK-KELILNEILVMRESK 673 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH 1015 H +I+ + +G+ L +VMEY+ GSL D + + Q+ ++ +G+ +LH Sbjct 674 HSNIVNFIDSYLAKGD--LWIVMEYMEGGSLTDVVTHCLLSEGQIGAVCRETLKGLQFLH 731 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 ++ +HRD+ + N+LL +K+ DFG + E + R G +P +W APE + Sbjct 732 SKGVLHRDIKSDNILLSLKGNIKLTDFGFCAQINENN-LKRTTMVG-TP-YWMAPEVVSR 788 Query 1076 YKFYYASDVWSFGVTLYELL 1095 ++ D+WS G+ + E++ Sbjct 789 KEYGPKVDIWSLGIMIIEMI 808 >sp|Q92772|CDKL2_HUMAN Cyclin-dependent kinase-like 2 OS=Homo sapiens OX=9606 GN=CDKL2 PE=1 SV=1 Length=493 Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 63/199 (32%), Positives = 101/199 (51%), Gaps = 18/199 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG +G V + C N TG +VA+K L++D + +EI +L+ L HE+++ Sbjct 10 VGEGSYGMV-MKC---RNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL----AQLLLFAQQICEGMAYLHAQ 1017 C + +K LV E+V ++ D L GL Q LF QI G+ + H+ Sbjct 66 LLEVC--KKKKRWYLVFEFVD-HTILDDLELFPNGLDYQVVQKYLF--QIINGIGFCHSH 120 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEY 1076 + IHRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L + Sbjct 121 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDV 177 Query 1077 KFYYASDVWSFGVTLYELL 1095 K+ A DVW+ G + E+ Sbjct 178 KYGKAVDVWAIGCLVTEMF 196 Score = 40.0 bits (92), Expect = 0.12, Method: Compositional matrix adjust. Identities = 41/160 (26%), Positives = 70/160 (44%), Gaps = 22/160 (14%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ---- 716 L+ Q+ H +L + VC + +V E+V+H LD + P V Q Sbjct 54 LLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILD-----DLELFPNGLDYQVVQKYLF 108 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVER 775 Q+ + + + + N++H ++ NIL+++ G+ +KL D G A E + Sbjct 109 QIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFARTLAAPGEVYTDY 161 Query 776 IP---WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 + + APE L G A+D W G + E+ F GE Sbjct 162 VATRWYRAPELLVGDV-KYGKAVDVWAIGCLVTEM-FMGE 199 >sp|Q16975|KPC2_APLCA Calcium-independent protein kinase C OS=Aplysia californica OX=6500 GN=PRKC2 PE=1 SV=1 Length=743 Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 62/205 (30%), Positives = 95/205 (46%), Gaps = 23/205 (11%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 I+ LG+G FGKV L GT E+ A+K LK D Q+ D+ T+ + I Sbjct 406 IKVLGKGSFGKVML----AEKKGTDEVYAIKVLKKDV-------IIQDDDVECTMTEKRI 454 Query 960 IKYKGC--------CEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEG 1010 + Q ++ L VMEYV G L + R + +A ++ Sbjct 455 LALSAKHPFLTALHSSFQTKERLFFVMEYVNGGDLMFQIQRARKFDEPRARFYAAEVTLA 514 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 + +LH I+RDL N+LLD + KI DFG+ K EG ++ + + AP Sbjct 515 LMFLHRHGIIYRDLKLDNILLDAEGHCKIADFGMCK---EGMTENKLTQTFCGTPDYIAP 571 Query 1071 ECLKEYKFYYASDVWSFGVTLYELL 1095 E L+E K+ + D W+ GV +YE++ Sbjct 572 EILQELKYDASVDWWALGVLMYEMM 596 >sp|P19525|E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2 Length=551 Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 76/282 (27%), Positives = 126/282 (45%), Gaps = 48/282 (17%) Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY---LKKIRDLGEGHFGKVSLYCYDPT 919 LR+ R +LA + PD + TV KR+ K+I +G G FG+V + Sbjct 232 LRNNQRKAKRSLAPRFDL-PDMKETKYTV-DKRFGMDFKEIELIGSGGFGQV----FKAK 285 Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGC----------CEDQ 969 + G+ +K +K + R E+ L L H +I+ Y GC +D Sbjct 286 HRIDGKTYVIKRVKYNNEKAER-----EVKALAKLDHVNIVHYNGCWDGFDYDPETSDDS 340 Query 970 GEKS-----------------LQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFA--QQICE 1009 E S L + ME+ G+L ++ R L ++L +QI + Sbjct 341 LESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITK 400 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 G+ Y+H++ IHRDL N+ L + + VKIGDFGL ++ ++ R R G + + + Sbjct 401 GVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLK--NDGKRTRSKG--TLRYMS 456 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111 PE + + D+++ G+ L ELL CD++ F +L Sbjct 457 PEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDL 498 Score = 43.5 bits (101), Expect = 0.011, Method: Compositional matrix adjust. Identities = 41/190 (22%), Positives = 83/190 (44%), Gaps = 29/190 (15%) Query 688 EYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 E+ + G L+ W+ + RG + + + +Q+ + Y+ +K L+H ++ NI L Sbjct 367 EFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFLV--- 423 Query 747 LAEGTSPFIKLSDPGVGLGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFG- 801 + +K+ D G+ + +L + + R + +++PE + + +D + G Sbjct 424 ----DTKQVKIGDFGL-VTSLKNDGKRTRSKGTLRYMSPEQIS--SQDYGKEVDLYALGL 476 Query 802 --ATLLEICFDGEAPLQSRSPSEKEHFYQ--RQHRLPEPSCPQLATLTSQCLTYEPTQRP 857 A LL +C + E F+ R + + + TL + L+ +P RP Sbjct 477 ILAELLHVC---------DTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRP 527 Query 858 SFRTILRDLT 867 + ILR LT Sbjct 528 NTSEILRTLT 537 >sp|O81292|LRK43_ARATH L-type lectin-domain containing receptor kinase IV.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK43 PE=2 SV=1 Length=674 Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 66/201 (33%), Positives = 99/201 (49%), Gaps = 21/201 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ---EIDILRTLYHEHI 959 LG G FG+V Y T + +AVK + + R G K+ EI + + H ++ Sbjct 361 LGSGGFGRV----YRGVMPTTKKEIAVKRVSN----ESRQGLKEFVAEIVSIGRMSHRNL 412 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA 1016 + G C + E L LV +Y+P GSL YL P ++ Q + G+ YLH Sbjct 413 VPLLGYCRRRDE--LLLVYDYMPNGSLDKYLYDCPEVTLDWKQRFNVIIGVASGLFYLHE 470 Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 Q IHRD+ A NVLLD + ++GDFGLA+ G + R G + AP+ + Sbjct 471 EWEQVVIHRDIKASNVLLDAEYNGRLGDFGLARLCDHGSDPQTTRVVGTWG--YLAPDHV 528 Query 1074 KEYKFYYASDVWSFGVTLYEL 1094 + + A+DV++FGV L E+ Sbjct 529 RTGRATTATDVFAFGVLLLEV 549 Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust. Identities = 57/234 (24%), Positives = 102/234 (44%), Gaps = 40/234 (17%) Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK--MVVAQQLA 719 + ++SH +L + G C R E ++V +Y+ +G LD +L + V + WK V +A Sbjct 404 IGRMSHRNLVPLLGYCRRRDELLLVYDYMPNGSLDKYL-YDCPEVTLDWKQRFNVIIGVA 462 Query 720 SALSYLE---NKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREERVER 775 S L YL + ++H ++ N+LL A G +L D G + + R Sbjct 463 SGLFYLHEEWEQVVIHRDIKASNVLLDAEYNGRLGDFGLARLCDHG-------SDPQTTR 515 Query 776 IP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF----- 826 + +LAP+ + G +TA D + FG LLE+ G P++ S++ Sbjct 516 VVGTWGYLAPDHVRTG--RATTATDVFAFGVLLLEVAC-GRRPIEIEIESDESVLLVDSV 572 Query 827 --YQRQHRLPEPSCPQLATLTSQ------------CLTYEPTQRPSFRTILRDL 866 + + + + + P L ++ Q C +P RP+ R +L+ L Sbjct 573 FGFWIEGNILDATDPNLGSVYDQREVETVLKLGLLCSHSDPQVRPTMRQVLQYL 626 >sp|Q8VYY5|NCRK_ARATH Receptor-like serine/threonine-protein kinase NCRK OS=Arabidopsis thaliana OX=3702 GN=NCRK PE=1 SV=1 Length=565 Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 82/275 (30%), Positives = 120/275 (44%), Gaps = 37/275 (13%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ--LVMEYV 981 G+ A+K L G + + E+++L L+H H++ G C + K + LV EY+ Sbjct 232 GKTAAIKRLNTPKGDDTDTLFSTEVELLSRLHHYHVVPLIGYCSEFHGKHAERLLVFEYM 291 Query 982 PLGSLRDYLPRHSIGLAQLLLFAQQI------CEGMAYLH---AQHYIHRDLAARNVLLD 1032 GSLRD L L + + + +I G+ YLH A +HRD+ + N+LLD Sbjct 292 SYGSLRDCLDGE---LGEKMTWNIRISVALGAARGLEYLHEAAAPRILHRDVKSTNILLD 348 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-------WYAPECLKEYKFYYASDVW 1085 + KI D G+AK + ++ SP ++APE SDV+ Sbjct 349 ENWHAKITDLGMAKCLSSDG----LQSGSSSPTTGLQGTFGYFAPEYAIAGCASQMSDVF 404 Query 1086 SFGVTLYELLTHCDSSQSPP-TKFLELIGIAQGQMTVLRLTELLERGERLPRP---DKCP 1141 SFGV L EL+T Q P K E + I V RL + E LP P K Sbjct 405 SFGVVLLELITGRKPIQKPSNNKGEESLVI----WAVPRLQDSKRVIEELPDPRLNGKFA 460 Query 1142 CEVYHLM----KNCWETEASFRPTFENLIPILKTV 1172 E +M K C + RPT ++ IL T+ Sbjct 461 EEEMQIMAYLAKECLLLDPESRPTMREVVQILSTI 495 Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 85/347 (24%), Positives = 144/347 (41%), Gaps = 79/347 (23%) Query 569 ASPRTLN--LSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 + P T++ + Q S+ ++Q + + S +G G + VY G+L+ +GK Sbjct 186 SKPETIHGAIFQFSYTELEQATNKFSSNSVIGHGGSSCVYRGQLK--------DGKT--- 234 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV----RG 680 + ++ P D F L+S++ H H+ + G C + Sbjct 235 -------------AAIKRLNTPKGDDTDTLFSTEVELLSRLHHYHVVPLIGYCSEFHGKH 281 Query 681 PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA--LSYLENK---NLVHGNV 735 E ++V EY+ +G L L E G M W + ++ L +A L YL ++H +V Sbjct 282 AERLLVFEYMSYGSLRDCLDGELGE-KMTWNIRISVALGAARGLEYLHEAAAPRILHRDV 340 Query 736 CGRNILL--------ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPE-CLP 785 NILL LG+A+ LS G+ G+ S ++ + APE + Sbjct 341 KSTNILLDENWHAKITDLGMAKC------LSSDGLQSGSSSPTTGLQGTFGYFAPEYAIA 394 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY--------QRQHR----L 833 G A+ +S D + FG LLE+ G P+Q S ++ E Q R L Sbjct 395 GCASQMS---DVFSFGVVLLEL-ITGRKPIQKPSNNKGEESLVIWAVPRLQDSKRVIEEL 450 Query 834 PEP---------SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P+P +A L +CL +P RP+ R +++ L+ + P Sbjct 451 PDPRLNGKFAEEEMQIMAYLAKECLLLDPESRPTMREVVQILSTITP 497 >sp|Q940H6|SRK2E_ARATH Serine/threonine-protein kinase SRK2E OS=Arabidopsis thaliana OX=3702 GN=SRK2E PE=1 SV=1 Length=362 Score = 77.4 bits (189), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 78/238 (33%), Positives = 113/238 (47%), Gaps = 26/238 (11%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 P P + + ++D+G G+FG L + + E+VAVK ++ G + Sbjct 9 PMDLPIMHDSDRYELVKDIGSGNFGVARLM----RDKQSNELVAVKYIER--GEKIDENV 62 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLL 1001 K+EI R+L H +I+++K L +VMEY G L + + R S A+ Sbjct 63 KREIINHRSLRHPNIVRFKEVI--LTPTHLAIVMEYASGGELFERICNAGRFSEDEARF- 119 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVR 1058 F QQ+ G++Y HA HRDL N LLD RL KI DFG +K+ + + + Sbjct 120 -FFQQLISGVSYCHAMQVCHRDLKLENTLLDGSPAPRL-KICDFGYSKS---SVLHSQPK 174 Query 1059 EDGDSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLELI 1112 +P + APE L KEY A DVWS GVTLY +L + P P F + I Sbjct 175 STVGTPA-YIAPEVLLKKEYDGKVA-DVWSCGVTLYVMLVGAYPFEDPEEPKNFRKTI 230 >sp|Q5R754|CDKL2_PONAB Cyclin-dependent kinase-like 2 OS=Pongo abelii OX=9601 GN=CDKL2 PE=2 SV=1 Length=493 Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 63/199 (32%), Positives = 101/199 (51%), Gaps = 18/199 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG +G V + C N TG +VA+K L++D + +EI +L+ L HE+++ Sbjct 10 VGEGSYGMV-MKC---RNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL----AQLLLFAQQICEGMAYLHAQ 1017 C+ + K LV E+V ++ D L GL Q LF QI G+ + H+ Sbjct 66 LLEVCKKK--KRWYLVFEFVD-HTILDDLELFPNGLDYQVVQKYLF--QIINGIGFCHSH 120 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEY 1076 + IHRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L + Sbjct 121 NIIHRDIKPENILVSKSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDV 177 Query 1077 KFYYASDVWSFGVTLYELL 1095 K+ A DVW+ G + E+ Sbjct 178 KYGKAVDVWAIGCLVTEMF 196 Score = 43.1 bits (100), Expect = 0.014, Method: Compositional matrix adjust. Identities = 57/236 (24%), Positives = 96/236 (41%), Gaps = 52/236 (22%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ---- 716 L+ Q+ H +L + VC + +V E+V+H LD + P V Q Sbjct 54 LLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILD-----DLELFPNGLDYQVVQKYLF 108 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVER 775 Q+ + + + + N++H ++ NIL+++ G+ +KL D G A E + Sbjct 109 QIINGIGFCHSHNIIHRDIKPENILVSKSGV-------VKLCDFGFARTLAAPGEVYTDY 161 Query 776 IP---WLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGEAP----------LQS 817 + + APE L G A+D W G + E+ F G++ L + Sbjct 162 VATRWYRAPELLVGDV-KYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGN 220 Query 818 RSPSEKEHFYQR----QHRLPEPS--------CPQLA----TLTSQCLTYEPTQRP 857 P +E FY+ RLPE P+L+ L +CL +P +RP Sbjct 221 LIPRHQELFYKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRP 276 >sp|Q8IBS5|CDPK4_PLAF7 Calcium-dependent protein kinase 4 OS=Plasmodium falciparum (isolate 3D7) OX=36329 GN=CDPK4 PE=1 SV=3 Length=528 Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 67/219 (31%), Positives = 108/219 (49%), Gaps = 25/219 (11%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQE 947 VF+++Y K I+ LG+G FG+V L + TG A+K + K + +E Sbjct 64 VVFNEQY-KGIKILGKGSFGEVIL----SRDKHTGHEYAIKVISKKHVKRKTDKESLLRE 118 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLF 1003 +++L+ L H +I+K ED LV + G L D + + I A+++ Sbjct 119 VELLKMLDHINIMKLYEFFEDNN--YYYLVSDVYTGGELFDEIISRKRFYEIDAARII-- 174 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDN----DRLVKIGDFGLAKAVPEGHEYYRVRE 1059 +QI G+ Y+H + +HRDL N+LL+ D ++KI DFGL+ EY + + Sbjct 175 -KQILSGITYMHKNNVVHRDLKPENILLETKNKEDMIIKIIDFGLSTHF----EYSKKMK 229 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 D ++ AP+ L + D+WS GV LY LL+ C Sbjct 230 DKIGTAYYIAPDVL-HGTYDEKCDIWSCGVILYILLSGC 267 >sp|O23082|CRK44_ARATH Cysteine-rich receptor-like protein kinase 44 OS=Arabidopsis thaliana OX=3702 GN=CRK44 PE=3 SV=2 Length=379 Score = 77.8 bits (190), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 63/210 (30%), Positives = 99/210 (47%), Gaps = 16/210 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG V D +GE +AVK L G Q + + E+ ++ L H ++++ Sbjct 62 LGEGGFGAVYKGVLD-----SGEEIAVKRLSMKSG-QGDNEFVNEVSLVAKLQHRNLVRL 115 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 G C +GE+ L L+ E+ SL ++ R + + + G+ YLH Sbjct 116 LGFCF-KGEERL-LIYEFFKNTSLEKFIFDSDRRMILDWEKRYRIISGVARGLLYLHEDS 173 Query 1019 Y---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074 + IHRD+ A NVLLD+ KI DFG+ K + + + Y APE Sbjct 174 HFKIIHRDMKASNVLLDDAMNPKIADFGMVKLFNTDQTSQTMFTSKVAGTYGYMAPEYAM 233 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 +F +DV+SFGV + E++ ++ SP Sbjct 234 SGQFSVKTDVFSFGVLVLEIIKGKKNNWSP 263 Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 67/325 (21%), Positives = 130/325 (40%), Gaps = 67/325 (21%) Query 576 LSQLSFH--RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L QL F R+ + + +HLG+G VY+G L D Sbjct 41 LLQLDFDTIRLATNDFSPYNHLGEGGFGAVYKGVL-----------------------DS 77 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 G+E+ V + D F SL++++ H +L + G C +G E +++ E+ ++ Sbjct 78 GEEIAVKRLSMKSGQGDNE--FVNEVSLVAKLQHRNLVRLLGFCFKGEERLLIYEFFKNT 135 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 L+ ++ + + W + + +A L YL + H + R++ + + L + Sbjct 136 SLEKFIFDSDRRMILDWEKRYRIISGVARGLLYLHEDS--HFKIIHRDMKASNVLLDDAM 193 Query 752 SPFIKLSDPGV----GLGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGAT 803 +P K++D G+ S+ ++ ++APE G S+ T D + FG Sbjct 194 NP--KIADFGMVKLFNTDQTSQTMFTSKVAGTYGYMAPEYAMSGQFSVKT--DVFSFGVL 249 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQH-----------RLPEPSCPQLATLTSQ----- 847 +LEI + + SP E+ + + + +PS + L+ + Sbjct 250 VLEII---KGKKNNWSPEEQSSLFLLSYVWKCWREGEVLNIVDPSLIETRGLSDEIRKCI 306 Query 848 -----CLTYEPTQRPSFRTILRDLT 867 C+ P RP+ +I+R L Sbjct 307 HIGLLCVQENPGSRPTMASIVRMLN 331 >sp|Q9S7U9|M2K2_ARATH Mitogen-activated protein kinase kinase 2 OS=Arabidopsis thaliana OX=3702 GN=MKK2 PE=1 SV=2 Length=363 Score = 77.4 bits (189), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 65/241 (27%), Positives = 115/241 (48%), Gaps = 29/241 (12%) Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922 +R +++L+P L+ P PA D L ++ +G+G G V L + Sbjct 44 VRIISQLEPEVLS------PIKPADDQLSLSD--LDMVKVIGKGSSGVVQLVQHK----W 91 Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982 TG+ A+K ++ + R QE+ I ++ +++ D G ++ L++EY+ Sbjct 92 TGQFFALKVIQLNIDEAIRKAIAQELKINQSSQCPNLVTSYQSFYDNG--AISLILEYMD 149 Query 983 LGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLH-AQHYIHRDLAARNVLLDNDRLVKIG 1040 GSL D+L +I + L +Q+ +G+ YLH +H IHRDL N+L+++ VKI Sbjct 150 GGSLADFLKSVKAIPDSYLSAIFRQVLQGLIYLHHDRHIIHRDLKPSNLLINHRGEVKIT 209 Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVF-----WYAPECLKEYKFYYASDVWSFGVTLYELL 1095 DFG++ + G + F + +PE + K+ SD+WS G+ + E Sbjct 210 DFGVSTVM--------TNTAGLANTFVGTYNYMSPERIVGNKYGNKSDIWSLGLVVLECA 261 Query 1096 T 1096 T Sbjct 262 T 262 Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust. Identities = 45/198 (23%), Positives = 87/198 (44%), Gaps = 32/198 (16%) Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE-NKNLVHGNVCGRNILLA 743 ++ EY++ G L +L+ + +P ++ + +Q+ L YL +++++H ++ N+L+ Sbjct 143 LILEYMDGGSLADFLKSVKA-IPDSYLSAIFRQVLQGLIYLHHDRHIIHRDLKPSNLLIN 201 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWG 799 G +K++D GV + V +++PE + G N D W Sbjct 202 HRGE-------VKITDFGVSTVMTNTAGLANTFVGTYNYMSPERIVG--NKYGNKSDIWS 252 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE----------PS---CPQLATLTS 846 G +LE C G+ P +P +E + L E PS P+L++ S Sbjct 253 LGLVVLE-CATGKFPY---APPNQEETWTSVFELMEAIVDQPPPALPSGNFSPELSSFIS 308 Query 847 QCLTYEPTQRPSFRTILR 864 CL +P R S + ++ Sbjct 309 TCLQKDPNSRSSAKELME 326 >sp|Q4R7T5|CDKL2_MACFA Cyclin-dependent kinase-like 2 OS=Macaca fascicularis OX=9541 GN=CDKL2 PE=2 SV=1 Length=570 Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 63/199 (32%), Positives = 101/199 (51%), Gaps = 18/199 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG +G V + C N TG +VA+K L++D + +EI +L+ L HE+++ Sbjct 10 VGEGSYGMV-VKC---RNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL----AQLLLFAQQICEGMAYLHAQ 1017 C + +K LV E+V ++ D L GL Q LF QI G+ + H+ Sbjct 66 LLEVC--KKKKRWYLVFEFVD-HTILDDLELFPNGLDYQVVQKYLF--QIINGIGFCHSH 120 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEY 1076 + IHRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L + Sbjct 121 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDV 177 Query 1077 KFYYASDVWSFGVTLYELL 1095 K+ A DVW+ G + E+ Sbjct 178 KYGKAVDVWAIGCLVTEMF 196 Score = 42.4 bits (98), Expect = 0.026, Method: Compositional matrix adjust. Identities = 56/236 (24%), Positives = 96/236 (41%), Gaps = 52/236 (22%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ---- 716 L+ Q+ H +L + VC + +V E+V+H LD + P V Q Sbjct 54 LLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILD-----DLELFPNGLDYQVVQKYLF 108 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVER 775 Q+ + + + + N++H ++ NIL+++ G+ +KL D G A E + Sbjct 109 QIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFARTLAAPGEVYTDY 161 Query 776 IP---WLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGEAPLQ----------S 817 + + APE L G A+D W G + E+ F G++ + + Sbjct 162 VATRWYRAPELLVGDV-KYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGN 220 Query 818 RSPSEKEHFYQR----QHRLPEPS--------CPQLA----TLTSQCLTYEPTQRP 857 P +E FY+ RLPE P+L+ L +CL +P +RP Sbjct 221 LIPRHQELFYKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRP 276 >sp|Q99014|KPC1_HYPJE Protein kinase C-like OS=Hypocrea jecorina OX=51453 GN=pkc1 PE=3 SV=1 Length=1139 Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 58/198 (29%), Positives = 89/198 (45%), Gaps = 14/198 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-----SGWKQEIDILRTLYHE 957 LG+G+FGKV L + + A+K LK + ++ K+ I H Sbjct 820 LGKGNFGKVML----AETKRSKRLFAIKVLKKEFIIENDEVESIKSEKRVFLIANRERHP 875 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 + C Q E + VMEY+ G L ++ R G + +A ++C + Y H Sbjct 876 FLTNLHACF--QTETRVYFVMEYISGGDLMLHIQRGQFGTKRAQFYAAEVCLALKYFHEN 933 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 I+RDL N++L D +KI D+GL K E Y + APE L + K Sbjct 934 GVIYRDLKLDNIMLTLDGHIKIADYGLCK---EDMWYGSTTSTFCGTPEFMAPEILLDKK 990 Query 1078 FYYASDVWSFGVTLYELL 1095 + A D W+FGV +Y++L Sbjct 991 YGRAVDWWAFGVLIYQML 1008 >sp|Q54WW7|Y0010_DICDI Probable serine/threonine-protein kinase DDB_G0279405 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0279405 PE=3 SV=1 Length=695 Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 69/209 (33%), Positives = 104/209 (50%), Gaps = 25/209 (12%) Query 900 IRDLGEGHFGKVSL-YCYDPTNDGTGEMVAVKAL------KADCG---PQHRSGWKQEID 949 +R LG+G FGKV L Y +D T + A+K K G P +EI Sbjct 204 VRKLGKGTFGKVKLAYHHD-----THHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIA 258 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICE 1009 I++ + H +++K D E+ + +VMEY+ GS+ S LA+ + + I Sbjct 259 IMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMS-ANETSEDLARK--YFRDIVF 315 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 G+ YLH Q IH+DL N+L++++ +VKI DFG++ + VR SP F A Sbjct 316 GLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDD---VVRCSRGSPAFL-A 371 Query 1070 PE-CLKEYKFYYAS--DVWSFGVTLYELL 1095 PE C E + DVW+ GV+LY L+ Sbjct 372 PELCRNESQPISGKGVDVWALGVSLYCLI 400 >sp|Q2PQN9|CDK5_GLOMM Cyclin-dependent kinase 5 homolog OS=Glossina morsitans morsitans OX=37546 GN=Cdk5 PE=2 SV=1 Length=292 Score = 76.3 bits (186), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 62/202 (31%), Positives = 100/202 (50%), Gaps = 16/202 (8%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYH 956 +K+ +GEG +G V + N T E+VA+K ++ D + S +EI +L+ L H Sbjct 5 EKLEKIGEGTYGTV----FKGRNRETLEIVALKRVRLDEDDEGVPSSALREICLLKELKH 60 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYL 1014 ++I++ EK L LV E+ L+ Y I +A F Q+ G+A+ Sbjct 61 KNIVRLYDVL--HSEKKLTLVFEHCD-QDLKKYFDSLNGDIDMAVCRSFMLQLLRGLAFC 117 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA-PECL 1073 H+ + +HRDL +N+L++ + +K+ DFGLA+A + Y + WY P+ L Sbjct 118 HSHNVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVKCY----SAEVVTLWYRPPDVL 173 Query 1074 KEYKFYYAS-DVWSFGVTLYEL 1094 K Y S D+WS G EL Sbjct 174 FGAKLYTTSIDMWSAGCIFAEL 195 >sp|Q9FXF2|RKF1_ARATH Probable LRR receptor-like serine/threonine-protein kinase RFK1 OS=Arabidopsis thaliana OX=3702 GN=RKF1 PE=1 SV=1 Length=1021 Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 63/208 (30%), Positives = 98/208 (47%), Gaps = 18/208 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG V G +VAVK L + +R + EI + L H +++K Sbjct 687 IGEGGFGAVFKGVL-----ADGRVVAVKQLSSKSRQGNRE-FLNEIGAISCLQHPNLVKL 740 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHS---IGLAQLLLFAQQICEGMAYLHAQ 1017 G C ++ + L L EY+ SL L P+H + I +G+A+LH + Sbjct 741 HGFCVERAQ--LLLAYEYMENNSLSSALFSPKHKQIPMDWPTRFKICCGIAKGLAFLHEE 798 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 ++HRD+ A N+LLD D KI DFGLA+ E + + G + + APE Sbjct 799 SPLKFVHRDIKATNILLDKDLTPKISDFGLARLDEEEKTHISTKVAGT--IGYMAPEYAL 856 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 + +DV+SFGV + E++ +S Sbjct 857 WGYLTFKADVYSFGVLVLEIVAGITNSN 884 Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 49/182 (27%), Positives = 79/182 (43%), Gaps = 24/182 (13%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K L F +S + H +L +HG CV + ++ EY+E+ L Sbjct 706 VAVKQLSSKSRQGNREFLNEIGAISCLQHPNLVKLHGFCVERAQLLLAYEYMENNSLSSA 765 Query 699 LRRER-GHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTS 752 L + +PM W + + +A L++L ++ VH ++ NILL + + Sbjct 766 LFSPKHKQIPMDWPTRFKICCGIAKGLAFLHEESPLKFVHRDIKATNILLDK-----DLT 820 Query 753 PFIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 P K+SD GL L EE+ I ++APE G L+ D + FG +L Sbjct 821 P--KISD--FGLARLDEEEKTHISTKVAGTIGYMAPEYALWGY--LTFKADVYSFGVLVL 874 Query 806 EI 807 EI Sbjct 875 EI 876 >sp|P83510|TNIK_MOUSE Traf2 and NCK-interacting protein kinase OS=Mus musculus OX=10090 GN=Tnik PE=1 SV=2 Length=1323 Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 56/205 (27%), Positives = 98/205 (48%), Gaps = 22/205 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961 +G G +G+V Y + TG++ A+K + D KQEI++L+ +H +I Sbjct 31 VGNGTYGQV----YKGRHVKTGQLAAIKVM--DVTGDEEEEIKQEINMLKKYSHHRNIAT 84 Query 962 YKGCCEDQG----EKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYL 1014 Y G + + L LVME+ GS+ D + +++ + ++I G+++L Sbjct 85 YYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHL 144 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H IHRD+ +NVLL + VK+ DFG++ + R +W APE + Sbjct 145 HQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQL---DRTVGRRNTFIGTPYWMAPEVIA 201 Query 1075 -----EYKFYYASDVWSFGVTLYEL 1094 + + + SD+WS G+T E+ Sbjct 202 CDENPDATYDFKSDLWSLGITAIEM 226 Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust. Identities = 55/255 (22%), Positives = 101/255 (40%), Gaps = 32/255 (13%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENI-----MVTEYVEH 692 +KV+D + + E L H ++A +G ++ P + +V E+ Sbjct 51 AAIKVMDVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGA 110 Query 693 GPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G + ++ +G+ + W + +++ LS+L ++H ++ G+N+LL Sbjct 111 GSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTE------- 163 Query 752 SPFIKLSDPGVGLG---ALSREERVERIP-WLAPECLPGGANSLST---AMDKWGFGATL 804 + +KL D GV + R P W+APE + N +T D W G T Sbjct 164 NAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITA 223 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS------CPQLATLTSQCLTYEPTQRPS 858 +E+ +G PL P R P P + + CL +QRP+ Sbjct 224 IEMA-EGAPPLCDMHPMRALFLIPRN---PAPRLKSKKWSKKFQSFIESCLVKNHSQRPA 279 Query 859 FRTILRD-LTRLQPH 872 +++ R QP+ Sbjct 280 TEQLMKHPFIRDQPN 294 >sp|Q9FIF1|LRK21_ARATH Probable L-type lectin-domain containing receptor kinase II.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK21 PE=2 SV=1 Length=674 Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 64/200 (32%), Positives = 96/200 (48%), Gaps = 17/200 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FGKV +G +AVK + D Q + EI + L H++++ Sbjct 361 LGAGGFGKVYKGILP-----SGTQIAVKRVYHDA-EQGMKQYVAEIASMGRLRHKNLVHL 414 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA-- 1016 G C +GE L LV +Y+P GSL DYL + + +Q + + + + YLH Sbjct 415 LGYCRRKGE--LLLVYDYMPNGSLDDYLFHKNKLKDLTWSQRVNIIKGVASALLYLHEEW 472 Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 Q +HRD+ A N+LLD D K+GDFGLA+ G R G + + APE Sbjct 473 EQVVLHRDIKASNILLDADLNGKLGDFGLARFHDRGVNLEATRVVG--TIGYMAPELTAM 530 Query 1076 YKFYYASDVWSFGVTLYELL 1095 +DV++FG + E++ Sbjct 531 GVTTTCTDVYAFGAFILEVV 550 Score = 62.0 bits (149), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 64/233 (27%), Positives = 103/233 (44%), Gaps = 30/233 (13%) Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVV 714 E AS M ++ H +L + G C R E ++V +Y+ +G LD +L + + W ++ + Sbjct 399 EIAS-MGRLRHKNLVHLLGYCRRKGELLLVYDYMPNGSLDDYLFHKNKLKDLTWSQRVNI 457 Query 715 AQQLASALSYLE---NKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + +ASAL YL + ++H ++ NILL A L G + D GV L A Sbjct 458 IKGVASALLYLHEEWEQVVLHRDIKASNILLDADLNGKLGDFGLARFHDRGVNLEA---T 514 Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-- 828 V I ++APE G +T D + FGA +LE+ G P+ +P E+ + Sbjct 515 RVVGTIGYMAPELTAMGVT--TTCTDVYAFGAFILEVVC-GRRPVDPDAPREQVILVKWV 571 Query 829 ----RQHRLPEPSCPQLATLTSQ-----------CLTYEPTQRPSFRTILRDL 866 ++ L + +L + C P RPS R IL+ L Sbjct 572 ASCGKRDALTDTVDSKLIDFKVEEAKLLLKLGMLCSQINPENRPSMRQILQYL 624 >sp|O95382|M3K6_HUMAN Mitogen-activated protein kinase kinase kinase 6 OS=Homo sapiens OX=9606 GN=MAP3K6 PE=1 SV=3 Length=1288 Score = 79.7 bits (195), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 65/206 (32%), Positives = 101/206 (49%), Gaps = 27/206 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ----EIDILRTLYHEH 958 LG+G +G V Y + T +A+K + P+ S + Q EI + R L H++ Sbjct 654 LGKGTYGVV----YAGRDRHTRVRIAIKEI-----PERDSRFSQPLHEEIALHRRLRHKN 704 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-----LAQLLLFAQQICEGMAY 1013 I++Y G G L++ ME VP GSL L R G + + + +QI +G+ Y Sbjct 705 IVRYLGSASQGG--YLKIFMEEVPGGSLSSLL-RSVWGPLKDNESTISFYTRQILQGLGY 761 Query 1014 LHAQHYIHRDLAARNVLLDN-DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 LH H +HRD+ NVL++ L+KI DFG +K + E + + APE Sbjct 762 LHDNHIVHRDIKGDNVLINTFSGLLKISDFGTSKRL---AGITPCTETFTGTLQYMAPEI 818 Query 1073 LKEYKFYY--ASDVWSFGVTLYELLT 1096 + + Y A+D+WS G T+ E+ T Sbjct 819 IDQGPRGYGKAADIWSLGCTVIEMAT 844 Score = 57.4 bits (137), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 58/247 (23%), Positives = 102/247 (41%), Gaps = 19/247 (8%) Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 GRDR +R+ +K + + +E +L ++ H ++ G +G + E Sbjct 665 GRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHRRLRHKNIVRYLGSASQGGYLKIFMEE 724 Query 690 VEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 V G L LR G + + +Q+ L YL + ++VH ++ G N+L+ Sbjct 725 VPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTF-- 782 Query 748 AEGTSPFIKLSDPGVG--LGALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 S +K+SD G L ++ E + ++APE + G A D W G T Sbjct 783 ----SGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCT 838 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCL---TYEPTQ--RPS 858 ++E+ G P + F +++ P P + +Q T+EP R S Sbjct 839 VIEMA-TGRPPFHELGSPQAAMFQVGMYKV-HPPMPSSLSAEAQAFLLRTFEPDPRLRAS 896 Query 859 FRTILRD 865 +T+L D Sbjct 897 AQTLLGD 903 >sp|Q39086|SD17_ARATH Receptor-like serine/threonine-protein kinase SD1-7 OS=Arabidopsis thaliana OX=3702 GN=SD17 PE=1 SV=1 Length=843 Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 65/202 (32%), Positives = 95/202 (47%), Gaps = 18/202 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V G+ +AVK L + Q + E+ ++ L H ++++ Sbjct 525 LGQGGFGIVY-----KGRLLDGKEIAVKRL-SKMSSQGTDEFMNEVRLIAKLQHINLVRL 578 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017 GCC D+GEK L+ EY+ SL +L ++ + I G+ YLH Sbjct 579 LGCCVDKGEK--MLIYEYLENLSLDSHLFDQTRSSNLNWQKRFDIINGIARGLLYLHQDS 636 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APECLK 1074 IHRDL A NVLLD + KI DFG+A+ G E + Y +PE Sbjct 637 RCRIIHRDLKASNVLLDKNMTPKISDFGMARIF--GREETEANTRRVVGTYGYMSPEYAM 694 Query 1075 EYKFYYASDVWSFGVTLYELLT 1096 + F SDV+SFGV L E+++ Sbjct 695 DGIFSMKSDVFSFGVLLLEIIS 716 Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 57/226 (25%), Positives = 95/226 (42%), Gaps = 45/226 (20%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 + LGQG VY+GRL +D G+E+ V K L Sbjct 523 NKLGQGGFGIVYKGRL------------LD-----------GKEIAV--KRLSKMSSQGT 557 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW-- 710 F L++++ H +L + G CV E +++ EY+E+ LD L + + W Sbjct 558 DEFMNEVRLIAKLQHINLVRLLGCCVDKGEKMLIYEYLENLSLDSHLFDQTRSSNLNWQK 617 Query 711 KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LG 765 + + +A L YL + ++H ++ N+LL + +P K+SD G+ G Sbjct 618 RFDIINGIARGLLYLHQDSRCRIIHRDLKASNVLLDK-----NMTP--KISDFGMARIFG 670 Query 766 ALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEI 807 E R+ +++PE G S+ + D + FG LLEI Sbjct 671 REETEANTRRVVGTYGYMSPEYAMDGIFSMKS--DVFSFGVLLLEI 714 >sp|Q9FHG4|LRKS7_ARATH Probable L-type lectin-domain containing receptor kinase S.7 OS=Arabidopsis thaliana OX=3702 GN=LECRKS7 PE=2 SV=1 Length=681 Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 58/203 (29%), Positives = 102/203 (50%), Gaps = 18/203 (9%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R +G G FG V Y +G + AVK + + + ++ + E+ I+ L H++++ Sbjct 369 RVIGRGAFGNV----YRAMFVSSGTISAVKRSRHNS-TEGKTEFLAELSIIACLRHKNLV 423 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYL 1014 + +G C ++GE L LV E++P GSL L + S + + L A + ++YL Sbjct 424 QLQGWCNEKGE--LLLVYEFMPNGSLDKILYQESQTGAVALDWSHRLNIAIGLASALSYL 481 Query 1015 H---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 H Q +HRD+ N++LD + ++GDFGLA+ H+ V + + APE Sbjct 482 HHECEQQVVHRDIKTSNIMLDINFNARLGDFGLARLTE--HDKSPVSTLTAGTMGYLAPE 539 Query 1072 CLKEYKFYYASDVWSFGVTLYEL 1094 L+ +D +S+GV + E+ Sbjct 540 YLQYGTATEKTDAFSYGVVILEV 562 >sp|Q9DGA5|CDK1_ORYCU Cyclin-dependent kinase 1 OS=Oryzias curvinotus OX=104658 GN=cdk1 PE=2 SV=1 Length=303 Score = 76.6 bits (187), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 65/215 (30%), Positives = 109/215 (51%), Gaps = 25/215 (12%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957 KI +GEG +G V Y + TG++VA+K ++ + + S +E+ +L+ L H Sbjct 6 KIEKIGEGTYGVV----YKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHP 61 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLL--FAQQICEGMAY 1013 ++++ E L L+ E++ + L+ YL G + +L+ + QI EG+ + Sbjct 62 NVVRLLDVL--MQESRLYLIFEFLSM-DLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYF 118 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA--VPEGHEYYRVREDGDSPVFWYAPE 1071 H + +HRDL +N+L+DN ++K+ DFGL++A VP RV +++ APE Sbjct 119 CHRRRVLHRDLKPQNLLIDNKGVIKLADFGLSRAFGVP-----VRVYTHEVVTLWYRAPE 173 Query 1072 C-LKEYKFYYASDVWSFGVTLYELLT-----HCDS 1100 L ++ DVWS G EL T H DS Sbjct 174 VLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDS 208 >sp|P11681|ABL_CALVI Tyrosine-protein kinase ABL (Fragment) OS=Calliphora vicina OX=7373 GN=ABL PE=3 SV=1 Length=74 Score = 70.1 bits (170), Expect = 1e-13, Method: Composition-based stats. Identities = 33/76 (43%), Positives = 48/76 (63%), Gaps = 2/76 (3%) Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 R ++ LL A QI GM+YL A++YIHRDLAARN L+ +++LVK+ DFGLA+ + + Sbjct 1 RETLDAVALLYMATQIASGMSYLEARNYIHRDLAARNCLVGDNKLVKVADFGLARLMRD- 59 Query 1052 HEYYRVREDGDSPVFW 1067 + Y P+ W Sbjct 60 -DTYTAHAGAKFPIKW 74 Score = 37.7 bits (86), Expect = 0.039, Method: Composition-based stats. Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 9/60 (15%) Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771 + +A Q+AS +SYLE +N +H ++ RN L+ G + +K++D GL L R++ Sbjct 10 LYMATQIASGMSYLEARNYIHRDLAARNCLV-------GDNKLVKVAD--FGLARLMRDD 60 >sp|Q9IA88|SIK2_CHICK Serine/threonine-protein kinase SIK2 OS=Gallus gallus OX=9031 GN=SIK2 PE=2 SV=1 Length=798 Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 66/223 (30%), Positives = 101/223 (45%), Gaps = 25/223 (11%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQH 940 P A+ P + R LG+G+F V L + T VA+K + K P + Sbjct 11 PAPSAAQPRPLRVGFYDIERTLGKGNFAVVKLARHRVTKT----QVAIKIIDKTRLDPSN 66 Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQ 999 +E+ I++ L H HIIK E + L +V E+ G + D+L + + ++ Sbjct 67 LEKIYREVQIMKLLNHPHIIKLYQVMETK--DMLYIVTEFAKNGEMFDHLTSNGHLSESE 124 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 QI + Y H+ H +HRDL N+LLD + +K+ DFG +Y+ E Sbjct 125 ARKKFWQILSAVEYCHSHHIVHRDLKTENLLLDANMNIKLADFGFGN-------FYKSGE 177 Query 1060 D-----GDSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELL 1095 G P + APE KEY+ + D+WS GV LY L+ Sbjct 178 PLSTWCGSPP--YAAPEVFEGKEYEGPHL-DIWSLGVVLYVLV 217 Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 58/243 (24%), Positives = 102/243 (42%), Gaps = 24/243 (10%) Query 630 GRDRGQELRVVLKVLDPSHHDIAL--AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 R R + +V +K++D + D + Y +M ++H H+ ++ V +VT Sbjct 43 ARHRVTKTQVAIKIIDKTRLDPSNLEKIYREVQIMKLLNHPHIIKLYQVMETKDMLYIVT 102 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 E+ ++G + L GH+ + Q+ SA+ Y + ++VH ++ N+LL Sbjct 103 EFAKNGEMFDHLT-SNGHLSESEARKKFWQILSAVEYCHSHHIVHRDLKTENLLL----- 156 Query 748 AEGTSPFIKLSDPGVGLGALSREERVE---RIPWLAPECLPGGANSLSTAMDKWGFGATL 804 + IKL+D G G S E P+ APE G +D W G L Sbjct 157 --DANMNIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYE-GPHLDIWSLGVVL 213 Query 805 -LEIC----FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859 + +C FDG P+ ++ + + R+P TL + L +PT+R + Sbjct 214 YVLVCGSLPFDG-----PNLPTLRQRVLEGRFRIPYFMSEDCETLIRRMLVVDPTKRITI 268 Query 860 RTI 862 I Sbjct 269 SQI 271 >sp|O49318|Y2317_ARATH Probable leucine-rich repeat receptor-like protein kinase At2g33170 OS=Arabidopsis thaliana OX=3702 GN=At2g33170 PE=2 SV=1 Length=1124 Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 60/188 (32%), Positives = 89/188 (47%), Gaps = 18/188 (10%) Query 923 TGEMVAVKALKADCGPQHRSG------WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976 +G+ +AVK L+++ + + ++ EI L + H +I++ C QG S L Sbjct 840 SGKTIAVKKLESNREGNNNNSNNTDNSFRAEILTLGKIRHRNIVRLYSFCYHQGSNSNLL 899 Query 977 VMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVL 1030 + EY+ GSL + L HS+ A EG+AYLH IHRD+ + N+L Sbjct 900 LYEYMSRGSLGELLHGGKSHSMDWPTRFAIALGAAEGLAYLHHDCKPRIIHRDIKSNNIL 959 Query 1031 LDNDRLVKIGDFGLAKAV--PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 +D + +GDFGLAK + P V + APE K D++SFG Sbjct 960 IDENFEAHVGDFGLAKVIDMPLSKSVSAVA----GSYGYIAPEYAYTMKVTEKCDIYSFG 1015 Query 1089 VTLYELLT 1096 V L ELLT Sbjct 1016 VVLLELLT 1023 >sp|Q9FIF0|LRK22_ARATH Putative L-type lectin-domain containing receptor kinase II.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK22 PE=3 SV=3 Length=694 Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 63/208 (30%), Positives = 101/208 (49%), Gaps = 17/208 (8%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R ++ R LG G FGKV +G +AVK + + Q + EI + L Sbjct 373 RGFRENRLLGAGGFGKVY-----KGELPSGTQIAVKRVYHNA-EQGMKQYAAEIASMGRL 426 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEG 1010 H+++++ G C +GE L LV +Y+P GSL DYL + + +Q + + + Sbjct 427 RHKNLVQLLGYCRRKGE--LLLVYDYMPNGSLDDYLFNKNKLKDLTWSQRVNIIKGVASA 484 Query 1011 MAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH Q +HRD+ A N+LLD D ++GDFGLA+ G R G + + Sbjct 485 LLYLHEEWEQVVLHRDIKASNILLDADLNGRLGDFGLARFHDRGENLQATRVVG--TIGY 542 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095 APE +D+++FG + E++ Sbjct 543 MAPELTAMGVATTKTDIYAFGSFILEVV 570 Score = 59.7 bits (143), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 62/233 (27%), Positives = 104/233 (45%), Gaps = 30/233 (13%) Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVV 714 E AS M ++ H +L + G C R E ++V +Y+ +G LD +L + + W ++ + Sbjct 419 EIAS-MGRLRHKNLVQLLGYCRRKGELLLVYDYMPNGSLDDYLFNKNKLKDLTWSQRVNI 477 Query 715 AQQLASALSYLE---NKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + +ASAL YL + ++H ++ NILL A L G + D G L A Sbjct 478 IKGVASALLYLHEEWEQVVLHRDIKASNILLDADLNGRLGDFGLARFHDRGENLQA---T 534 Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-- 828 V I ++APE G +T D + FG+ +LE+ G P++ P E+ H + Sbjct 535 RVVGTIGYMAPELTAMGV--ATTKTDIYAFGSFILEVVC-GRRPVEPDRPPEQMHLLKWV 591 Query 829 ----RQHRLPEPSCPQLATLTSQ-----------CLTYEPTQRPSFRTILRDL 866 ++ L + +L ++ C P RPS R I++ L Sbjct 592 ATCGKRDTLMDVVDSKLGDFKAKEAKLLLKLGMLCSQSNPESRPSMRHIIQYL 644 >sp|P0C5D6|SAPK3_ORYSJ Serine/threonine-protein kinase SAPK3 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK3 PE=1 SV=1 Length=334 Score = 77.0 bits (188), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 73/212 (34%), Positives = 107/212 (50%), Gaps = 23/212 (11%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 +RY + +++LG G+FG L + + E+VAVK ++ G + ++EI Sbjct 1 MEERY-EALKELGAGNFGVARLV----RDKRSKELVAVKYIER--GKKIDENVQREIINH 53 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQIC 1008 R+L H +II++K C L +VMEY G L + + R S A+ F QQ+ Sbjct 54 RSLRHPNIIRFKEVC--LTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARY--FFQQLI 109 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRL--VKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G++Y H+ HRDL N LLD VKI DFG +K+ + + + +P Sbjct 110 SGVSYCHSLEICHRDLKLENTLLDGSPTPRVKICDFGYSKS---ALLHSKPKSTVGTPA- 165 Query 1067 WYAPECL--KEYKFYYASDVWSFGVTLYELLT 1096 + APE L KEY A DVWS GVTLY +L Sbjct 166 YIAPEVLSRKEYDGKVA-DVWSCGVTLYVMLV 196 >sp|A2ZAB5|SAPK3_ORYSI Serine/threonine-protein kinase SAPK3 OS=Oryza sativa subsp. indica OX=39946 GN=SAPK3 PE=1 SV=2 Length=334 Score = 77.0 bits (188), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 73/212 (34%), Positives = 107/212 (50%), Gaps = 23/212 (11%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 +RY + +++LG G+FG L + + E+VAVK ++ G + ++EI Sbjct 1 MEERY-EALKELGAGNFGVARLV----RDKRSKELVAVKYIER--GKKIDENVQREIINH 53 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQIC 1008 R+L H +II++K C L +VMEY G L + + R S A+ F QQ+ Sbjct 54 RSLRHPNIIRFKEVC--LTPTHLAIVMEYAAGGELFEQICTAGRFSEDEARY--FFQQLI 109 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRL--VKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G++Y H+ HRDL N LLD VKI DFG +K+ + + + +P Sbjct 110 SGVSYCHSLEICHRDLKLENTLLDGSPTPRVKICDFGYSKS---ALLHSKPKSTVGTPA- 165 Query 1067 WYAPECL--KEYKFYYASDVWSFGVTLYELLT 1096 + APE L KEY A DVWS GVTLY +L Sbjct 166 YIAPEVLSRKEYDGKVA-DVWSCGVTLYVMLV 196 >sp|Q9XEC7|CRK37_ARATH Cysteine-rich receptor-like protein kinase 37 OS=Arabidopsis thaliana OX=3702 GN=CRK37 PE=3 SV=1 Length=646 Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 65/205 (32%), Positives = 97/205 (47%), Gaps = 24/205 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V +G+ +AVK L+ G Q +K E+ +L L H +++K Sbjct 351 LGQGGFGSVYKGILP-----SGQEIAVKRLRKGSG-QGGMEFKNEVLLLTRLQHRNLVKL 404 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017 G C ++ E+ L V E+VP SL ++ R + + + G+ YLH Sbjct 405 LGFCNEKDEEIL--VYEFVPNSSLDHFIFDEEKRRVLTWDVRYTIIEGVARGLLYLHEDS 462 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAV----PEGHEYYRVREDGDSPVFWYAPE 1071 IHRDL A N+LLD + K+ DFG+A+ G V G + APE Sbjct 463 QLRIIHRDLKASNILLDAEMNPKVADFGMARLFDMDETRGQTSRVVGTYG-----YMAPE 517 Query 1072 CLKEYKFYYASDVWSFGVTLYELLT 1096 +F SDV+SFGV L E+++ Sbjct 518 YATYGQFSTKSDVYSFGVMLLEMIS 542 Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 49/180 (27%), Positives = 78/180 (43%), Gaps = 12/180 (7%) Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 GQE+ V K L + F L++++ H +L + G C E I+V E+V + Sbjct 367 GQEIAV--KRLRKGSGQGGMEFKNEVLLLTRLQHRNLVKLLGFCNEKDEEILVYEFVPNS 424 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILL-ARLGL 747 LD ++ E + W + + + +A L YL + ++H ++ NILL A + Sbjct 425 SLDHFIFDEEKRRVLTWDVRYTIIEGVARGLLYLHEDSQLRIIHRDLKASNILLDAEMNP 484 Query 748 AEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +L D G SR V ++APE G ST D + FG LLE+ Sbjct 485 KVADFGMARLFDMDETRGQTSRV--VGTYGYMAPEYATYG--QFSTKSDVYSFGVMLLEM 540 >sp|P39951|CDK1_RAT Cyclin-dependent kinase 1 OS=Rattus norvegicus OX=10116 GN=Cdk1 PE=1 SV=1 Length=297 Score = 76.3 bits (186), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 62/233 (27%), Positives = 110/233 (47%), Gaps = 23/233 (10%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957 KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L H Sbjct 6 KIEKIGEGTYGVV----YKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAY 1013 +I+ + + L L+ E++ + L+ YL P + + + + QI +G+ + Sbjct 62 NIVSLQDVL--MQDSRLYLIFEFLSM-DLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVF 118 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072 H++ +HRDL +N+L+D+ +K+ DFGLA+A Y + WY +PE Sbjct 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYT----HEVVTLWYRSPEV 174 Query 1073 -LKEYKFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQM 1119 L ++ D+WS G EL T H DS + +G ++ Sbjct 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV 227 >sp|Q9SN43|CIPKC_ARATH CBL-interacting serine/threonine-protein kinase 12 OS=Arabidopsis thaliana OX=3702 GN=CIPK12 PE=1 SV=1 Length=489 Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 65/203 (32%), Positives = 99/203 (49%), Gaps = 24/203 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYHEH 958 LG G F KV Y N T E VA+K + D + G K+EI ILR + H + Sbjct 32 LGHGTFAKV----YLARNVKTNESVAIKVI--DKEKVLKGGLIAHIKREISILRRVRHPN 85 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I++ + + + VMEYV G L + + + + + QQ+ + + HA+ Sbjct 86 IVQLFEVMATKAK--IYFVMEYVRGGELFNKVAKGRLKEEVARKYFQQLISAVTFCHARG 143 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF-----WYAPECL 1073 HRDL N+LLD + +K+ DFGL+ AV + ++R+DG F + APE L Sbjct 144 VYHRDLKPENLLLDENGNLKVSDFGLS-AVSD-----QIRQDGLFHTFCGTPAYVAPEVL 197 Query 1074 KEYKFYYAS-DVWSFGVTLYELL 1095 + A D+WS GV L+ L+ Sbjct 198 ARKGYDAAKVDIWSCGVILFVLM 220 Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 53/215 (25%), Positives = 93/215 (43%), Gaps = 22/215 (10%) Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLA 719 S++ +V H ++ + V + V EYV G L + + R +A K QQL Sbjct 76 SILRRVRHPNIVQLFEVMATKAKIYFVMEYVRGGELFNKVAKGRLKEEVARKYF--QQLI 133 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--- 776 SA+++ + + H ++ N+LL G +K+SD GL A+S + R + + Sbjct 134 SAVTFCHARGVYHRDLKPENLLLDENG-------NLKVSD--FGLSAVSDQIRQDGLFHT 184 Query 777 -----PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP-SEKEHFYQRQ 830 ++APE L + +D W G L + G P R+ + + Y+ + Sbjct 185 FCGTPAYVAPEVLARKGYD-AAKVDIWSCGVILF-VLMAGYLPFHDRNVMAMYKKIYRGE 242 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 R P +L L S+ L P +R +F I+ + Sbjct 243 FRCPRWFSTELTRLLSKLLETNPEKRFTFPEIMEN 277 >sp|Q5BBL3|STE20_EMENI Serine/threonine-protein kinase ste20 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=ste20 PE=3 SV=1 Length=848 Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 53/208 (25%), Positives = 98/208 (47%), Gaps = 14/208 (7%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DPT + + +G+G G V Y+ T VA+K + D P+ + E Sbjct 562 DPTKLYY----NLNKIGQGASGGV-FTAYE---QHTNNCVAIKQMNLDLQPK-KDLIINE 612 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQI 1007 I +++ H++I+ + + L +VMEY+ GSL D + + + Q+ ++ Sbjct 613 ILVMKDSKHKNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMSEPQIAAVCRET 670 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 G+ +LH++ IHRD+ + N+LL D +K+ DFG + ++ R +W Sbjct 671 LNGLQHLHSKGVIHRDIKSDNILLSLDGNIKLTDFGFCAQI---NDSQNKRNTMVGTPYW 727 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELL 1095 APE + ++ D+WS G+ E++ Sbjct 728 MAPEVVTRKEYGRKVDIWSLGIMAIEMI 755 Score = 37.7 bits (86), Expect = 0.72, Method: Compositional matrix adjust. Identities = 42/165 (25%), Positives = 69/165 (42%), Gaps = 18/165 (11%) Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL-DVWLRRERGHVPMAWKMVVAQQLA 719 +M H ++ + G + +V EY+E G L DV +A V ++ Sbjct 615 VMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVVTFNIMSEPQIA---AVCRETL 671 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERVER 775 + L +L +K ++H ++ NILL+ G IKL+D G + R V Sbjct 672 NGLQHLHSKGVIHRDIKSDNILLSLDG-------NIKLTDFGFCAQINDSQNKRNTMVGT 724 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 W+APE + +D W G +E+ +GE P + SP Sbjct 725 PYWMAPEVV--TRKEYGRKVDIWSLGIMAIEM-IEGEPPYLTESP 766 >sp|P11440|CDK1_MOUSE Cyclin-dependent kinase 1 OS=Mus musculus OX=10090 GN=Cdk1 PE=1 SV=3 Length=297 Score = 76.3 bits (186), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 62/233 (27%), Positives = 110/233 (47%), Gaps = 23/233 (10%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHE 957 KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L H Sbjct 6 KIEKIGEGTYGVV----YKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAY 1013 +I+ + + L L+ E++ + L+ YL P + + + + QI +G+ + Sbjct 62 NIVSLQDVL--MQDSRLYLIFEFLSM-DLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVF 118 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072 H++ +HRDL +N+L+D+ +K+ DFGLA+A Y + WY +PE Sbjct 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYT----HEVVTLWYRSPEV 174 Query 1073 -LKEYKFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQM 1119 L ++ D+WS G EL T H DS + +G ++ Sbjct 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV 227 >sp|Q9ZVM9|Y1461_ARATH Probable serine/threonine-protein kinase At1g54610 OS=Arabidopsis thaliana OX=3702 GN=At1g54610 PE=1 SV=1 Length=572 Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 61/205 (30%), Positives = 99/205 (48%), Gaps = 13/205 (6%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLY 955 +KI +G+G + V Y + TG++VA+K ++ D P+ +EI +LR L Sbjct 118 FEKIDKIGQGTYSNV----YKAKDMLTGKIVALKKVRFDNLEPESVKFMAREILVLRRLD 173 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVP--LGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013 H +++K +G + SL LV +Y+ L L P +++ +Q+ G+ + Sbjct 174 HPNVVKLEGLVTSRMSCSLYLVFQYMDHDLAGLASS-PVVKFSESEVKCLMRQLISGLEH 232 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY-APEC 1072 H++ +HRD+ N+L+D+ ++KI DFGLA H+ WY APE Sbjct 233 CHSRGVLHRDIKGSNLLIDDGGVLKIADFGLATIFDPNHKRPMTSR---VVTLWYRAPEL 289 Query 1073 LKEYKFY-YASDVWSFGVTLYELLT 1096 L Y D+WS G L ELL Sbjct 290 LLGATDYGVGIDLWSAGCILAELLA 314 >sp|Q7XUF4|CDKG2_ORYSJ Cyclin-dependent kinase G-2 OS=Oryza sativa subsp. japonica OX=39947 GN=CDKG-2 PE=2 SV=2 Length=710 Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 66/209 (32%), Positives = 101/209 (48%), Gaps = 22/209 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILR 952 +++ + EG +G V Y + TGE+VA+K +K + + R G+ +EI+IL Sbjct 365 FERLNKINEGTYGVV----YRARDKKTGEIVALKKVKME---KEREGFPLTSLREINILL 417 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQICE 1009 + +H I+ K S+ +VMEY+ G + +S + L+ Q+ E Sbjct 418 SFHHPSIVDVKEVVVGSSLDSIFMVMEYMEHDLKGVMEAMKQPYSQSEVKCLML--QLLE 475 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068 G+ YLH +HRDL N+LL+N +KI DFGL++ + Y WY Sbjct 476 GVKYLHDNWVLHRDLKTSNLLLNNRGELKICDFGLSRQYGSPLKPYTQL----VVTLWYR 531 Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLT 1096 APE L K Y A D+WS G + ELL Sbjct 532 APELLLGTKEYSTAIDMWSVGCIMAELLA 560 >sp|A2XUW1|CDKG2_ORYSI Cyclin-dependent kinase G-2 OS=Oryza sativa subsp. indica OX=39946 GN=CDKG-2 PE=3 SV=1 Length=710 Score = 79.0 bits (193), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 66/209 (32%), Positives = 101/209 (48%), Gaps = 22/209 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK----QEIDILR 952 +++ + EG +G V Y + TGE+VA+K +K + + R G+ +EI+IL Sbjct 365 FERLNKINEGTYGVV----YRARDKKTGEIVALKKVKME---KEREGFPLTSLREINILL 417 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVP---LGSLRDYLPRHSIGLAQLLLFAQQICE 1009 + +H I+ K S+ +VMEY+ G + +S + L+ Q+ E Sbjct 418 SFHHPSIVDVKEVVVGSSLDSIFMVMEYMEHDLKGVMEAMKQPYSQSEVKCLML--QLLE 475 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY- 1068 G+ YLH +HRDL N+LL+N +KI DFGL++ + Y WY Sbjct 476 GVKYLHDNWVLHRDLKTSNLLLNNRGELKICDFGLSRQYGSPLKPYTQL----VVTLWYR 531 Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLT 1096 APE L K Y A D+WS G + ELL Sbjct 532 APELLLGTKEYSTAIDMWSVGCIMAELLA 560 >sp|Q940A2|P2C31_ARATH Protein kinase and PP2C-like domain-containing protein OS=Arabidopsis thaliana OX=3702 GN=At2g40860/At2g40870 PE=2 SV=1 Length=658 Score = 79.0 bits (193), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 55/206 (27%), Positives = 97/206 (47%), Gaps = 28/206 (14%) Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY- 1054 + Q+LL + + + YLH +HRD+ NVLLD + DFGLA+ E Sbjct 122 SIDQVLLITLHLAKALQYLHNNGIVHRDVKPANVLLDEKFFPYLADFGLAEYKKNLREVN 181 Query 1055 -YRVREDGD-----------SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT----HC 1098 R G + + APE L++ + +D++SFG+ + ELLT + Sbjct 182 LQNWRSSGKPTGGFHKKNMVGTLIYMAPEILRKDMYTEKADIYSFGILINELLTGVVPYT 241 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTE-----LLERGERLPRPDKCPCEVYHLMKNCWE 1153 D + + + Q+TV ++ L E G LP+ + L++NCWE Sbjct 242 DRRAEAQAHTVLEMNYTEQQLTVAIVSSGLRPALAEIGLHLPK------SLLSLIQNCWE 295 Query 1154 TEASFRPTFENLIPILKTVHEKYQGQ 1179 ++ S RP+ +N++ L+++ E+ +G+ Sbjct 296 SDPSKRPSSDNVVLELESIWEQVRGK 321 Score = 47.4 bits (111), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 55/248 (22%), Positives = 97/248 (39%), Gaps = 36/248 (15%) Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F+ L ++H +A + + P + ++ E G L L E + +++ Sbjct 70 FHRNLQLSCNLNHPGVAKLLAAHAKPPNYMFFFDFYESGTLAEKLHVEEWSPSIDQVLLI 129 Query 715 AQQLASALSYLENKNLVHGNVCGRNIL--------LARLGLAEGTSPFIKLS-----DPG 761 LA AL YL N +VH +V N+L LA GLAE +++ G Sbjct 130 TLHLAKALQYLHNNGIVHRDVKPANVLLDEKFFPYLADFGLAEYKKNLREVNLQNWRSSG 189 Query 762 VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 G ++ V + ++APE L + + D + FG + E+ G P R Sbjct 190 KPTGGFHKKNMVGTLIYMAPEILR--KDMYTEKADIYSFGILINEL-LTGVVPYTDRRAE 246 Query 822 EKEH------FYQRQHRLPEPSC---PQLA-----------TLTSQCLTYEPTQRPSFRT 861 + H + ++Q + S P LA +L C +P++RPS Sbjct 247 AQAHTVLEMNYTEQQLTVAIVSSGLRPALAEIGLHLPKSLLSLIQNCWESDPSKRPSSDN 306 Query 862 ILRDLTRL 869 ++ +L + Sbjct 307 VVLELESI 314 >sp|O74536|SNF1_SCHPO SNF1-like protein kinase ssp2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ssp2 PE=1 SV=1 Length=576 Score = 78.6 bits (192), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 72/216 (33%), Positives = 106/216 (49%), Gaps = 20/216 (9%) Query 889 PTVFHKRYLKK--IRD-LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 P KR++ IR+ LGEG FGKV L T+ T + VA+K + + + Sbjct 23 PEAISKRHIGPYIIRETLGEGSFGKVKL----ATHYKTQQKVALKFISRQLLKKSDMHMR 78 Query 946 --QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLL 1002 +EI L+ L H HIIK + + +V+EY G L DY+ + + + Sbjct 79 VEREISYLKLLRHPHIIKLYDVITTPTD--IVMVIEYAG-GELFDYIVEKKRMTEDEGRR 135 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 F QQI + Y H +HRDL N+LLD++ VKI DFGL+ + +G+ ++ Sbjct 136 FFQQIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGN---FLKTSCG 192 Query 1063 SPVFWYAPECLKEYKFYYA--SDVWSFGVTLYELLT 1096 SP + APE + K Y DVWS G+ LY +L Sbjct 193 SPNYA-APEVING-KLYAGPEVDVWSCGIVLYVMLV 226 Score = 35.4 bits (80), Expect = 3.5, Method: Compositional matrix adjust. Identities = 44/222 (20%), Positives = 87/222 (39%), Gaps = 19/222 (9%) Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 D+ + S + + H H+ ++ V + +MV EY D + ++R Sbjct 74 DMHMRVEREISYLKLLRHPHIIKLYDVITTPTDIVMVIEYAGGELFDYIVEKKRMTEDEG 133 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 + QQ+ A+ Y +VH ++ N+LL + +K++D GL + Sbjct 134 RRFF--QQIICAIEYCHRHKIVHRDLKPENLLL-------DDNLNVKIAD--FGLSNIMT 182 Query 770 EERVERIP-----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR-SPSEK 823 + + + APE + G + +D W G +L + G P P+ Sbjct 183 DGNFLKTSCGSPNYAAPEVINGKLYA-GPEVDVWSCG-IVLYVMLVGRLPFDDEFIPNLF 240 Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + + +P+ P +L + + +P QR + + I RD Sbjct 241 KKVNSCVYVMPDFLSPGAQSLIRRMIVADPMQRITIQEIRRD 282 >sp|Q8H1D6|RBK1_ARATH Receptor-like cytosolic serine/threonine-protein kinase RBK1 OS=Arabidopsis thaliana OX=3702 GN=RBK1 PE=1 SV=1 Length=467 Score = 78.2 bits (191), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 59/181 (33%), Positives = 91/181 (50%), Gaps = 11/181 (6%) Query 923 TGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 GE VA+K L + + S + E+ I+ + H + + +G D+G L V+EY Sbjct 174 NGETVAIKKLMSHAKEEEERVSDFLSELGIIAHVNHPNAARLRGFSSDRG---LHFVLEY 230 Query 981 VPLGSLRDYLPRHSIGLAQLLLF--AQQICEGMAYLHA---QHYIHRDLAARNVLLDNDR 1035 P GSL L L + + A I +G++YLH + IHRD+ A N+LL++D Sbjct 231 APYGSLASMLFGSEECLEWKIRYKVALGIADGLSYLHNACPRRIIHRDIKASNILLNHDY 290 Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 +I DFGLAK +PE ++ V + + APE DV++FGV L E++ Sbjct 291 EAQISDFGLAKWLPENWPHHVVFPI-EGTFGYLAPEYFMHGIVDEKIDVFAFGVLLLEII 349 Query 1096 T 1096 T Sbjct 350 T 350 >sp|Q6ICW6|WNK11_ARATH Probable serine/threonine-protein kinase WNK11 OS=Arabidopsis thaliana OX=3702 GN=WNK11 PE=2 SV=1 Length=314 Score = 76.6 bits (187), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 69/226 (31%), Positives = 106/226 (47%), Gaps = 25/226 (11%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC---GPQHRSGW 944 DPT + RY + LG G KV Y + G VA +K C P Sbjct 25 DPTGRYGRYGEL---LGSGAVKKV----YRAFDQEEGIEVAWNQVKLRCFSDDPAMTERL 77 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLF 1003 E+ +L+ L + +II D+ +L + E G+LR+Y +H + + L + Sbjct 78 YSEVRLLKNLKNSNIITLYKVWRDERNNTLNFITEICTSGNLREYRKKHRHVSMRALKKW 137 Query 1004 AQQICEGMAYLHAQH--YIHRDLAARNVLLD-NDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 ++QI +G+ YLH IHRDL N+ ++ N VKIGD GLA V + H + + Sbjct 138 SKQILKGLDYLHTHDPCIIHRDLNCSNIFVNGNIGQVKIGDLGLAAIVGKNHLAHSIL-- 195 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL------THCDS 1100 +P F APE L E + D++S+G+ + EL+ + CDS Sbjct 196 -GTPEFM-APE-LYEENYTEMVDIYSYGMCVLELVSLEIPYSECDS 238 Lambda K H a alpha 0.321 0.138 0.435 0.792 4.96 Gapped Lambda K H a alpha sigma 0.267 0.0410 0.140 1.90 42.6 43.6 Effective search space used: 140973851148 Results from round 2 Query= sp|P29597|TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 OS=Homo sapiens OX=9606 GN=TYK2 PE=1 SV=3 Length=1187 Score E Sequences producing significant alignments: (Bits) Value Sequences used in model and found again: sp|P29597|TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 OS... 1630 0.0 sp|Q9R117|TYK2_MOUSE Non-receptor tyrosine-protein kinase TYK2 OS... 1498 0.0 sp|O12990|JAK1_DANRE Tyrosine-protein kinase JAK1 OS=Danio rerio ... 1224 0.0 sp|P23458|JAK1_HUMAN Tyrosine-protein kinase JAK1 OS=Homo sapiens... 1219 0.0 sp|P52332|JAK1_MOUSE Tyrosine-protein kinase JAK1 OS=Mus musculus... 1219 0.0 sp|Q75R65|JAK2_CHICK Tyrosine-protein kinase JAK2 OS=Gallus gallu... 1172 0.0 sp|Q09178|JAK1_CYPCA Tyrosine-protein kinase JAK1 OS=Cyprinus car... 1164 0.0 sp|Q5RB23|JAK2_PONAB Tyrosine-protein kinase JAK2 OS=Pongo abelii... 1147 0.0 sp|O60674|JAK2_HUMAN Tyrosine-protein kinase JAK2 OS=Homo sapiens... 1145 0.0 sp|Q62689|JAK2_RAT Tyrosine-protein kinase JAK2 OS=Rattus norvegi... 1139 0.0 sp|O19064|JAK2_PIG Tyrosine-protein kinase JAK2 OS=Sus scrofa OX=... 1138 0.0 sp|Q62120|JAK2_MOUSE Tyrosine-protein kinase JAK2 OS=Mus musculus... 1131 0.0 sp|Q62137|JAK3_MOUSE Tyrosine-protein kinase JAK3 OS=Mus musculus... 1036 0.0 sp|P52333|JAK3_HUMAN Tyrosine-protein kinase JAK3 OS=Homo sapiens... 1036 0.0 sp|Q63272|JAK3_RAT Tyrosine-protein kinase JAK3 OS=Rattus norvegi... 1025 0.0 sp|Q24592|JAK_DROME Tyrosine-protein kinase hopscotch OS=Drosophi... 416 1e-124 sp|P42688|SRK2_SPOLA Tyrosine-protein kinase SRK2 (Fragment) OS=S... 323 3e-99 sp|P42690|SRK4_SPOLA Tyrosine-protein kinase isoform SRK4 OS=Spon... 323 1e-97 sp|Q54I36|PYK3_DICDI Dual specificity protein kinase pyk3 OS=Dict... 342 4e-97 sp|P42686|SRK1_SPOLA Tyrosine-protein kinase isoform SRK1 OS=Spon... 320 1e-96 sp|P18652|KS6AA_CHICK Ribosomal protein S6 kinase 2 alpha OS=Gall... 326 1e-95 sp|Q9UK32|KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 OS=Homo... 325 1e-95 sp|Q62662|FRK_RAT Tyrosine-protein kinase FRK OS=Rattus norvegicu... 318 1e-95 sp|O45539|SRC2_CAEEL Tyrosine protein-kinase src-2 OS=Caenorhabdi... 318 1e-95 sp|P00528|SRC64_DROME Tyrosine-protein kinase Src64B OS=Drosophil... 319 1e-95 sp|Q552C6|ZAK2_DICDI Dual specificity protein kinase zak2 OS=Dict... 320 8e-95 sp|P42685|FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo sapiens O... 314 2e-94 sp|Q922K9|FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus musculus O... 315 3e-94 sp|P27446|FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiphophorus he... 312 3e-93 sp|Q9V9J3|SRC42_DROME Tyrosine-protein kinase Src42A OS=Drosophil... 311 8e-93 sp|Q02977|YRK_CHICK Proto-oncogene tyrosine-protein kinase Yrk OS... 311 8e-93 sp|Q6EWH2|FYNA_DANRE Tyrosine-protein kinase fyna OS=Danio rerio ... 310 2e-92 sp|P13406|FYN_XENLA Tyrosine-protein kinase Fyn OS=Xenopus laevis... 310 2e-92 sp|P10936|YES_XENLA Tyrosine-protein kinase Yes OS=Xenopus laevis... 308 1e-91 sp|P09324|YES_CHICK Tyrosine-protein kinase Yes OS=Gallus gallus ... 308 2e-91 sp|P13116|SRC2_XENLA Tyrosine-protein kinase Src-2 OS=Xenopus lae... 307 2e-91 sp|P00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src OS... 307 2e-91 sp|P39688|FYN_MOUSE Tyrosine-protein kinase Fyn OS=Mus musculus O... 307 2e-91 sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo sapiens O... 307 3e-91 sp|Q62844|FYN_RAT Tyrosine-protein kinase Fyn OS=Rattus norvegicu... 307 3e-91 sp|A1Y2K1|FYN_PIG Tyrosine-protein kinase Fyn OS=Sus scrofa OX=98... 307 3e-91 sp|A0JNB0|FYN_BOVIN Tyrosine-protein kinase Fyn OS=Bos taurus OX=... 307 3e-91 sp|P14084|SRC_AVISS Tyrosine-protein kinase transforming protein ... 308 3e-91 sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src OS... 306 4e-91 sp|Q9TTY2|FER_CANLF Tyrosine-protein kinase Fer OS=Canis lupus fa... 315 4e-91 sp|P70451|FER_MOUSE Tyrosine-protein kinase Fer OS=Mus musculus O... 315 5e-91 sp|P14085|SRC_AVIST Tyrosine-protein kinase transforming protein ... 307 6e-91 sp|P00525|SRC_AVISR Tyrosine-protein kinase transforming protein ... 305 7e-91 sp|P63185|SRC_RSVSE Tyrosine-protein kinase transforming protein ... 305 1e-90 sp|P15054|SRC_AVIS2 Tyrosine-protein kinase transforming protein ... 307 1e-90 sp|P09760|FER_RAT Tyrosine-protein kinase Fer OS=Rattus norvegicu... 313 1e-90 sp|P05480|SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src OS... 305 2e-90 sp|Q9WUD9|SRC_RAT Proto-oncogene tyrosine-protein kinase Src OS=R... 305 2e-90 sp|P07947|YES_HUMAN Tyrosine-protein kinase Yes OS=Homo sapiens O... 305 3e-90 sp|Q05876|FYN_CHICK Tyrosine-protein kinase Fyn OS=Gallus gallus ... 304 3e-90 sp|F1RDG9|FYNB_DANRE Tyrosine-protein kinase fynb OS=Danio rerio ... 305 3e-90 sp|P31693|SRC_RSVPA Tyrosine-protein kinase transforming protein ... 303 3e-90 sp|P00524|SRC_RSVSA Tyrosine-protein kinase transforming protein ... 303 5e-90 sp|P17713|STK_HYDVU Tyrosine-protein kinase STK OS=Hydra vulgaris... 302 6e-90 sp|A1A5H8|YES_DANRE Tyrosine-protein kinase yes OS=Danio rerio OX... 303 7e-90 sp|P00527|YES_AVISY Tyrosine-protein kinase transforming protein ... 303 7e-90 sp|P27447|YES_XIPHE Tyrosine-protein kinase Yes OS=Xiphophorus he... 303 9e-90 sp|Q04736|YES_MOUSE Tyrosine-protein kinase Yes OS=Mus musculus O... 303 1e-89 sp|Q1JPZ3|SRC_DANRE Proto-oncogene tyrosine-protein kinase Src OS... 302 1e-89 sp|P13115|SRC1_XENLA Tyrosine-protein kinase Src-1 OS=Xenopus lae... 302 2e-89 sp|Q6P6U0|FGR_RAT Tyrosine-protein kinase Fgr OS=Rattus norvegicu... 301 3e-89 sp|F1LM93|YES_RAT Tyrosine-protein kinase Yes OS=Rattus norvegicu... 301 6e-89 sp|P14234|FGR_MOUSE Tyrosine-protein kinase Fgr OS=Mus musculus O... 299 1e-88 sp|P10447|ABL_FSVHY Tyrosine-protein kinase transforming protein ... 296 2e-88 sp|P00526|SRC_RSVP Tyrosine-protein kinase transforming protein S... 299 2e-88 sp|P25020|SRC_RSVH1 Tyrosine-protein kinase transforming protein ... 298 3e-88 sp|P16591|FER_HUMAN Tyrosine-protein kinase Fer OS=Homo sapiens O... 306 4e-88 sp|Q28923|YES_CANLF Tyrosine-protein kinase Yes OS=Canis lupus fa... 298 6e-88 sp|O13148|EPA4A_DANRE Ephrin type-A receptor 4a (Fragment) OS=Dan... 288 1e-87 sp|G5EE56|SRC1_CAEEL Tyrosine protein-kinase src-1 OS=Caenorhabdi... 297 1e-87 sp|P00521|ABL_MLVAB Tyrosine-protein kinase transforming protein ... 303 2e-87 sp|P09769|FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo sapiens O... 294 2e-86 sp|P54755|EPHA5_CHICK Ephrin type-A receptor 5 OS=Gallus gallus O... 305 4e-86 sp|Q60629|EPHA5_MOUSE Ephrin type-A receptor 5 OS=Mus musculus OX... 302 4e-86 sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens O... 292 5e-86 sp|P25911|LYN_MOUSE Tyrosine-protein kinase Lyn OS=Mus musculus O... 292 5e-86 sp|P00543|FES_FSVST Tyrosine-protein kinase transforming protein ... 290 6e-86 sp|Q07014|LYN_RAT Tyrosine-protein kinase Lyn OS=Rattus norvegicu... 291 7e-86 sp|Q95KR7|LCK_SAISC Proto-oncogene tyrosine-protein kinase LCK OS... 291 1e-85 sp|P42683|LCK_CHICK Proto-oncogene tyrosine-protein kinase LCK OS... 291 1e-85 sp|P42689|SRK3_SPOLA Tyrosine-protein kinase SRK3 (Fragment) OS=S... 283 3e-85 sp|Q01621|LCK_RAT Proto-oncogene tyrosine-protein kinase LCK OS=R... 289 4e-85 sp|P06240|LCK_MOUSE Proto-oncogene tyrosine-protein kinase LCK OS... 289 4e-85 sp|Q95M30|HCK_MACFA Tyrosine-protein kinase HCK OS=Macaca fascicu... 288 6e-85 sp|P00542|FES_FSVGA Tyrosine-protein kinase transforming protein ... 292 7e-85 sp|P29320|EPHA3_HUMAN Ephrin type-A receptor 3 OS=Homo sapiens OX... 300 9e-85 sp|P00544|FGR_FSVGR Tyrosine-protein kinase transforming protein ... 289 9e-85 sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens... 303 1e-84 sp|P00520|ABL1_MOUSE Tyrosine-protein kinase ABL1 OS=Mus musculus... 303 1e-84 sp|P06239|LCK_HUMAN Tyrosine-protein kinase Lck OS=Homo sapiens O... 288 1e-84 sp|Q5PXS1|LCK_AOTNA Tyrosine-protein kinase Lck OS=Aotus nancymaa... 288 1e-84 sp|P54756|EPHA5_HUMAN Ephrin type-A receptor 5 OS=Homo sapiens OX... 301 2e-84 sp|P08631|HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo sapiens O... 288 2e-84 sp|P54757|EPHA5_RAT Ephrin type-A receptor 5 OS=Rattus norvegicus... 299 5e-84 sp|P29321|EPHA8_RAT Ephrin type-A receptor 8 (Fragment) OS=Rattus... 281 6e-84 sp|P14238|FES_FELCA Tyrosine-protein kinase Fes/Fps OS=Felis catu... 295 7e-84 sp|Q03145|EPHA2_MOUSE Ephrin type-A receptor 2 OS=Mus musculus OX... 297 1e-83 sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens... 300 1e-83 sp|O08680|EPHA3_RAT Ephrin type-A receptor 3 OS=Rattus norvegicus... 297 1e-83 sp|P00522|ABL_DROME Tyrosine-protein kinase Abl OS=Drosophila mel... 303 2e-83 sp|P29318|EPHA3_CHICK Ephrin type-A receptor 3 OS=Gallus gallus O... 296 3e-83 sp|P16879|FES_MOUSE Tyrosine-protein kinase Fes/Fps OS=Mus muscul... 293 4e-83 sp|P00541|FPS_AVISP Tyrosine-protein kinase transforming protein ... 285 4e-83 sp|O13146|EPHA3_DANRE Ephrin type-A receptor 3 OS=Danio rerio OX=... 295 1e-82 sp|P29319|EPHA3_MOUSE Ephrin type-A receptor 3 OS=Mus musculus OX... 295 1e-82 sp|Q4JIM5|ABL2_MOUSE Tyrosine-protein kinase ABL2 OS=Mus musculus... 297 2e-82 sp|P08103|HCK_MOUSE Tyrosine-protein kinase HCK OS=Mus musculus O... 282 2e-82 sp|P16277|BLK_MOUSE Tyrosine-protein kinase Blk OS=Mus musculus O... 281 2e-82 sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens OX... 293 3e-82 sp|P42681|TXK_HUMAN Tyrosine-protein kinase TXK OS=Homo sapiens O... 282 3e-82 sp|P07332|FES_HUMAN Tyrosine-protein kinase Fes/Fps OS=Homo sapie... 290 4e-82 sp|P50545|HCK_RAT Tyrosine-protein kinase HCK OS=Rattus norvegicu... 281 4e-82 sp|P42682|TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus musculus O... 281 6e-82 sp|Q91736|EPB1B_XENLA Ephrin type-B receptor 1-B (Fragment) OS=Xe... 291 6e-82 sp|Q91694|EPA4B_XENLA Ephrin type-A receptor 4-B OS=Xenopus laevi... 292 9e-82 sp|Q91845|EPA4A_XENLA Ephrin type-A receptor 4-A OS=Xenopus laevi... 291 1e-81 sp|P54763|EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus musculus OX... 291 1e-81 sp|P21802|FGFR2_HUMAN Fibroblast growth factor receptor 2 OS=Homo... 288 1e-81 sp|Q1KL86|EPHA2_MACFA Ephrin type-A receptor 2 OS=Macaca fascicul... 291 1e-81 sp|P21804|FGFR1_CHICK Fibroblast growth factor receptor 1 OS=Gall... 288 1e-81 sp|P18461|FGFR2_CHICK Fibroblast growth factor receptor 2 OS=Gall... 288 2e-81 sp|Q61772|EPHA7_MOUSE Ephrin type-A receptor 7 OS=Mus musculus OX... 291 2e-81 sp|O42422|EPHA7_CHICK Ephrin type-A receptor 7 OS=Gallus gallus O... 291 3e-81 sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens OX... 291 3e-81 sp|P54759|EPHA7_RAT Ephrin type-A receptor 7 OS=Rattus norvegicus... 290 4e-81 sp|Q15375|EPHA7_HUMAN Ephrin type-A receptor 7 OS=Homo sapiens OX... 290 4e-81 sp|P28693|EPHB2_CHICK Ephrin type-B receptor 2 OS=Gallus gallus O... 290 4e-81 sp|P16092|FGFR1_MOUSE Fibroblast growth factor receptor 1 OS=Mus ... 287 4e-81 sp|Q03137|EPHA4_MOUSE Ephrin type-A receptor 4 OS=Mus musculus OX... 290 4e-81 sp|P54764|EPHA4_HUMAN Ephrin type-A receptor 4 OS=Homo sapiens OX... 290 4e-81 sp|Q07496|EPHA4_CHICK Ephrin type-A receptor 4 OS=Gallus gallus O... 290 4e-81 sp|P11362|FGFR1_HUMAN Fibroblast growth factor receptor 1 OS=Homo... 287 4e-81 sp|Q04589|FGFR1_RAT Fibroblast growth factor receptor 1 OS=Rattus... 286 5e-81 sp|P21803|FGFR2_MOUSE Fibroblast growth factor receptor 2 OS=Mus ... 286 6e-81 sp|P09759|EPHB1_RAT Ephrin type-B receptor 1 OS=Rattus norvegicus... 290 7e-81 sp|Q8CBF3|EPHB1_MOUSE Ephrin type-B receptor 1 OS=Mus musculus OX... 290 7e-81 sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo sapiens OX... 289 9e-81 sp|Q91287|FGFR3_PLEWA Fibroblast growth factor receptor 3 OS=Pleu... 285 1e-80 sp|P03949|ABL1_CAEEL Tyrosine-protein kinase abl-1 OS=Caenorhabdi... 292 1e-80 sp|Q91147|FGFR2_NOTVI Fibroblast growth factor receptor 2 OS=Noto... 283 1e-80 sp|Q91285|FGFR1_PLEWA Fibroblast growth factor receptor 1 OS=Pleu... 285 2e-80 sp|P18460|FGFR3_CHICK Fibroblast growth factor receptor 3 OS=Gall... 285 2e-80 sp|Q64434|PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus musculus OX... 274 2e-80 sp|Q13882|PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo sapiens OX... 274 3e-80 sp|Q91735|EPHB3_XENLA Ephrin type-B receptor 3 OS=Xenopus laevis ... 287 3e-80 sp|P22607|FGFR3_HUMAN Fibroblast growth factor receptor 3 OS=Homo... 284 3e-80 sp|Q8JH64|BTK_CHICK Tyrosine-protein kinase BTK OS=Gallus gallus ... 280 4e-80 sp|Q90344|EPHB2_COTJA Ephrin type-B receptor 2 OS=Coturnix japoni... 287 4e-80 sp|Q8JG38|FGFR2_DANRE Fibroblast growth factor receptor 2 OS=Dani... 284 4e-80 sp|O13147|EPHB3_DANRE Ephrin type-B receptor 3 (Fragment) OS=Dani... 275 4e-80 sp|Q0VBZ0|CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos taurus OX=... 273 5e-80 sp|P41240|CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo sapiens O... 273 6e-80 sp|P22182|FGFR1_XENLA Fibroblast growth factor receptor 1 OS=Xeno... 283 7e-80 sp|P32577|CSK_RAT Tyrosine-protein kinase CSK OS=Rattus norvegicu... 273 7e-80 sp|P41241|CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus musculus O... 272 1e-79 sp|Q498D6|FGFR4_RAT Fibroblast growth factor receptor 4 OS=Rattus... 282 1e-79 sp|P42680|TEC_HUMAN Tyrosine-protein kinase Tec OS=Homo sapiens O... 278 1e-79 sp|Q91288|FGFR4_PLEWA Fibroblast growth factor receptor 4 OS=Pleu... 282 2e-79 sp|Q61851|FGFR3_MOUSE Fibroblast growth factor receptor 3 OS=Mus ... 282 2e-79 sp|Q03364|FGFR2_XENLA Fibroblast growth factor receptor 2 OS=Xeno... 282 2e-79 sp|Q91286|FGFR2_PLEWA Fibroblast growth factor receptor 2 OS=Pleu... 281 3e-79 sp|Q07494|EPHB1_CHICK Ephrin type-B receptor 1 (Fragment) OS=Gall... 285 3e-79 sp|P51451|BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo sapiens O... 272 4e-79 sp|P24604|TEC_MOUSE Tyrosine-protein kinase Tec OS=Mus musculus O... 276 4e-79 sp|Q90Z00|FGR1A_DANRE Fibroblast growth factor receptor 1-A OS=Da... 281 4e-79 sp|P27450|CST_ARATH Probable serine/threonine-protein kinase CST ... 269 4e-79 sp|Q5XF79|PBL18_ARATH Probable serine/threonine-protein kinase PB... 268 5e-79 sp|P41239|CSK_CHICK Tyrosine-protein kinase CSK OS=Gallus gallus ... 270 5e-79 sp|Q07497|EPHB5_CHICK Ephrin type-B receptor 5 OS=Gallus gallus O... 284 5e-79 sp|Q6VNS1|NTRK3_MOUSE NT-3 growth factor receptor OS=Mus musculus... 281 6e-79 sp|Q91044|NTRK3_CHICK NT-3 growth factor receptor OS=Gallus gallu... 281 6e-79 sp|P29322|EPHA8_HUMAN Ephrin type-A receptor 8 OS=Homo sapiens OX... 284 7e-79 sp|Q91987|NTRK2_CHICK BDNF/NT-3 growth factors receptor OS=Gallus... 280 8e-79 sp|Q5IFJ9|NTRK3_MACFA NT-3 growth factor receptor OS=Macaca fasci... 280 9e-79 sp|Q5IS37|NTRK3_PANTR NT-3 growth factor receptor OS=Pan troglody... 280 9e-79 sp|Q54H45|DRKB_DICDI Probable serine/threonine-protein kinase drk... 277 1e-78 sp|P54754|EPHB3_MOUSE Ephrin type-B receptor 3 OS=Mus musculus OX... 283 1e-78 sp|Q86PM4|FGFR_HYDVU Fibroblast growth factor receptor OS=Hydra v... 280 1e-78 sp|Q3UFB7|NTRK1_MOUSE High affinity nerve growth factor receptor ... 278 2e-78 sp|Q90413|FGFR4_DANRE Fibroblast growth factor receptor 4 OS=Dani... 281 2e-78 sp|O42127|FGFR3_XENLA Fibroblast growth factor receptor 3 OS=Xeno... 278 2e-78 sp|P22455|FGFR4_HUMAN Fibroblast growth factor receptor 4 OS=Homo... 278 3e-78 sp|Q06187|BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo sapiens O... 275 3e-78 sp|P00530|FPS_FUJSV Tyrosine-protein kinase transforming protein ... 280 3e-78 sp|P24786|NTRK3_PIG NT-3 growth factor receptor OS=Sus scrofa OX=... 278 4e-78 sp|P35739|NTRK1_RAT High affinity nerve growth factor receptor OS... 278 4e-78 sp|O22558|STY8_ARATH Serine/threonine-protein kinase STY8 OS=Arab... 271 4e-78 sp|F4JTP5|STY46_ARATH Serine/threonine-protein kinase STY46 OS=Ar... 272 4e-78 sp|P35991|BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus musculus O... 274 6e-78 sp|O48814|BIK1_ARATH Serine/threonine-protein kinase BIK1 OS=Arab... 265 7e-78 sp|P54758|EPHA6_RAT Ephrin type-A receptor 6 OS=Rattus norvegicus... 281 7e-78 sp|Q9LTC0|PBL19_ARATH Probable serine/threonine-protein kinase PB... 265 1e-77 sp|Q07407|FGFR1_DROME Fibroblast growth factor receptor homolog 1... 275 1e-77 sp|Q5IS82|NTRK3_SAIBB NT-3 growth factor receptor OS=Saimiri boli... 276 2e-77 sp|Q2MHE4|HT1_ARATH Serine/threonine/tyrosine-protein kinase HT1 ... 264 2e-77 sp|Q90330|FGFR4_COTCO Fibroblast growth factor receptor 4 OS=Cotu... 273 3e-77 sp|Q91571|EPB1A_XENLA Ephrin type-B receptor 1-A OS=Xenopus laevi... 279 4e-77 sp|P53356|HTK16_HYDVU Tyrosine-protein kinase HTK16 OS=Hydra vulg... 274 4e-77 sp|Q9I8X3|FGFR3_DANRE Fibroblast growth factor receptor 3 OS=Dani... 275 4e-77 sp|Q08881|ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=Homo sapie... 270 5e-77 sp|Q8GXZ3|PBL8_ARATH Probable serine/threonine-protein kinase PBL... 263 6e-77 sp|Q5PP29|PBL4_ARATH Probable serine/threonine-protein kinase PBL... 263 6e-77 sp|Q9LFP7|PBL34_ARATH Serine/threonine-protein kinase PBL34 OS=Ar... 266 8e-77 sp|P41242|MATK_MOUSE Megakaryocyte-associated tyrosine-protein ki... 266 8e-77 sp|O73878|EPB4B_DANRE Ephrin type-B receptor 4b OS=Danio rerio OX... 277 9e-77 sp|P54761|EPHB4_MOUSE Ephrin type-B receptor 4 OS=Mus musculus OX... 278 9e-77 sp|Q63604|NTRK2_RAT BDNF/NT-3 growth factors receptor OS=Rattus n... 274 9e-77 sp|P54753|EPHB3_HUMAN Ephrin type-B receptor 3 OS=Homo sapiens OX... 278 9e-77 sp|P00529|ROS_AVISU Tyrosine-protein kinase transforming protein ... 262 1e-76 sp|Q65XV8|RK176_ORYSJ Receptor-like cytoplasmic kinase 176 OS=Ory... 261 1e-76 sp|P08630|BTKL_DROME Tyrosine-protein kinase Btk OS=Drosophila me... 273 1e-76 sp|P15209|NTRK2_MOUSE BDNF/NT-3 growth factors receptor OS=Mus mu... 274 1e-76 sp|Q16620|NTRK2_HUMAN BDNF/NT-3 growth factors receptor OS=Homo s... 274 1e-76 sp|Q54H46|DRKA_DICDI Probable serine/threonine-protein kinase drk... 269 2e-76 sp|P43293|PBL11_ARATH Probable serine/threonine-protein kinase PB... 261 2e-76 sp|O09127|EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus musculus OX... 276 2e-76 sp|P41243|MATK_RAT Megakaryocyte-associated tyrosine-protein kina... 263 2e-76 sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens OX... 276 3e-76 sp|Q07498|EPHB3_CHICK Ephrin type-B receptor 3 (Fragment) OS=Gall... 276 3e-76 sp|Q55GU0|Y9955_DICDI Probable serine/threonine-protein kinase DD... 275 4e-76 sp|G5ECJ6|CSK1_CAEEL Tyrosine-protein kinase csk-1 OS=Caenorhabdi... 265 4e-76 sp|Q9SFT7|PBL26_ARATH Probable serine/threonine-protein kinase PB... 261 4e-76 sp|Q8RWL6|STY17_ARATH Serine/threonine-protein kinase STY17 OS=Ar... 266 5e-76 sp|Q9SRH7|PBL35_ARATH Serine/threonine-protein kinase PBL35 OS=Ar... 263 5e-76 sp|Q62413|EPHA6_MOUSE Ephrin type-A receptor 6 OS=Mus musculus OX... 276 5e-76 sp|Q03142|FGFR4_MOUSE Fibroblast growth factor receptor 4 OS=Mus ... 271 9e-76 sp|Q62270|SRMS_MOUSE Tyrosine-protein kinase Srms OS=Mus musculus... 263 1e-75 sp|Q9UF33|EPHA6_HUMAN Ephrin type-A receptor 6 OS=Homo sapiens OX... 275 1e-75 sp|Q91743|FGFR4_XENLA Fibroblast growth factor receptor 4 OS=Xeno... 271 1e-75 sp|Q8H186|PBL1_ARATH Probable serine/threonine-protein kinase PBL... 259 1e-75 sp|O73875|EPB4A_DANRE Ephrin type-B receptor 4a OS=Danio rerio OX... 274 1e-75 sp|P43404|ZAP70_MOUSE Tyrosine-protein kinase ZAP-70 OS=Mus muscu... 266 1e-75 sp|P46573|PBL10_ARATH Probable serine/threonine-protein kinase PB... 259 1e-75 sp|Q03526|ITK_MOUSE Tyrosine-protein kinase ITK/TSK OS=Mus muscul... 266 1e-75 sp|Q9SII6|PIX13_ARATH Probable serine/threonine-protein kinase PI... 259 2e-75 sp|Q16288|NTRK3_HUMAN NT-3 growth factor receptor OS=Homo sapiens... 271 2e-75 sp|Q9C9U5|SIS8_ARATH Probable serine/threonine-protein kinase SIS... 274 2e-75 sp|Q24488|ROR1_DROME Tyrosine-protein kinase transmembrane recept... 267 2e-75 sp|Q9FE20|PBS1_ARATH Serine/threonine-protein kinase PBS1 OS=Arab... 260 3e-75 sp|Q06548|PBL9_ARATH Probable serine/threonine-protein kinase PBL... 258 3e-75 sp|Q84M95|PBL28_ARATH Probable serine/threonine-protein kinase PB... 257 4e-75 sp|P43403|ZAP70_HUMAN Tyrosine-protein kinase ZAP-70 OS=Homo sapi... 265 4e-75 sp|P33497|RYK_AVIR3 Tyrosine-protein kinase transforming protein ... 259 4e-75 sp|Q54TM7|DRKD_DICDI Probable serine/threonine-protein kinase drk... 275 6e-75 sp|Q9H3Y6|SRMS_HUMAN Tyrosine-protein kinase Srms OS=Homo sapiens... 260 7e-75 sp|Q9LDZ5|PBL21_ARATH Probable serine/threonine-protein kinase PB... 256 7e-75 sp|P04629|NTRK1_HUMAN High affinity nerve growth factor receptor ... 268 8e-75 sp|P42679|MATK_HUMAN Megakaryocyte-associated tyrosine-protein ki... 260 1e-74 sp|P07949|RET_HUMAN Proto-oncogene tyrosine-protein kinase recept... 273 1e-74 sp|Q91009|NTRK1_CHICK High affinity nerve growth factor receptor ... 267 1e-74 sp|Q06807|TIE2_BOVIN Angiopoietin-1 receptor OS=Bos taurus OX=991... 273 1e-74 sp|Q4H3K6|FGFR_CIOIN Fibroblast growth factor receptor OS=Ciona i... 266 1e-74 sp|G3V9H8|RET_RAT Proto-oncogene tyrosine-protein kinase receptor... 273 1e-74 sp|Q02763|TIE2_HUMAN Angiopoietin-1 receptor OS=Homo sapiens OX=9... 273 1e-74 sp|Q02858|TIE2_MOUSE Angiopoietin-1 receptor OS=Mus musculus OX=1... 273 2e-74 sp|Q8VYG0|LRL13_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 264 2e-74 sp|Q0WRY5|PBL7_ARATH Probable serine/threonine-protein kinase PBL... 254 2e-74 sp|Q95YM9|FGFR_HALRO Fibroblast growth factor receptor OS=Halocyn... 266 2e-74 sp|P16056|MET_MOUSE Hepatocyte growth factor receptor OS=Mus musc... 274 3e-74 sp|F4J0D2|PBL36_ARATH Serine/threonine-protein kinase PBL36 OS=Ar... 258 3e-74 sp|O15146|MUSK_HUMAN Muscle, skeletal receptor tyrosine-protein k... 268 3e-74 sp|Q7TPS0|KS6A6_MOUSE Ribosomal protein S6 kinase alpha-6 OS=Mus ... 266 3e-74 sp|Q9LRY1|PBL25_ARATH Probable serine/threonine-protein kinase PB... 254 3e-74 sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens OX=9... 271 3e-74 sp|P21709|EPHA1_HUMAN Ephrin type-A receptor 1 OS=Homo sapiens OX... 270 3e-74 sp|Q09YN5|MET_RABIT Hepatocyte growth factor receptor OS=Oryctola... 273 4e-74 sp|P70600|FAK2_RAT Protein-tyrosine kinase 2-beta OS=Rattus norve... 270 4e-74 sp|Q5UQG7|YR818_MIMIV Putative serine/threonine-protein kinase/re... 274 4e-74 sp|P35546|RET_MOUSE Proto-oncogene tyrosine-protein kinase recept... 271 4e-74 sp|Q9SY91|PBL15_ARATH Probable serine/threonine-protein kinase PB... 255 5e-74 sp|Q7T6Y2|YR831_MIMIV Putative serine/threonine-protein kinase/re... 274 5e-74 sp|Q2QLH6|MET_OTOGA Hepatocyte growth factor receptor OS=Otolemur... 273 5e-74 sp|P18106|FER_DROME Tyrosine-protein kinase Fer OS=Drosophila mel... 273 6e-74 sp|Q9SFX0|PBL22_ARATH Probable serine/threonine-protein kinase PB... 253 7e-74 sp|Q2IBC0|MET_RHIFE Hepatocyte growth factor receptor OS=Rhinolop... 273 7e-74 sp|Q9QVP9|FAK2_MOUSE Protein-tyrosine kinase 2-beta OS=Mus muscul... 270 7e-74 sp|Q9VBW3|CAD96_DROME Tyrosine kinase receptor Cad96Ca OS=Drosoph... 265 7e-74 sp|Q2QLG5|MET_CALJA Hepatocyte growth factor receptor OS=Callithr... 273 8e-74 sp|Q1PDV6|PBL27_ARATH Serine/threonine-protein kinase PBL27 OS=Ar... 258 8e-74 sp|Q8AXY6|MUSK_CHICK Muscle, skeletal receptor tyrosine protein k... 268 9e-74 sp|Q2QL89|MET_MICMU Hepatocyte growth factor receptor OS=Microceb... 272 1e-73 sp|Q2QLC0|MET_PLEMO Hepatocyte growth factor receptor OS=Plecturo... 272 1e-73 sp|Q07DY1|MET_NOMLE Hepatocyte growth factor receptor OS=Nomascus... 272 1e-73 sp|P08581|MET_HUMAN Hepatocyte growth factor receptor OS=Homo sap... 272 1e-73 sp|Q2IBF2|MET_GORGO Hepatocyte growth factor receptor OS=Gorilla ... 272 1e-73 sp|Q2QLF1|MET_PANTR Hepatocyte growth factor receptor OS=Pan trog... 272 1e-73 sp|Q2IBD8|MET_PONAB Hepatocyte growth factor receptor OS=Pongo ab... 272 1e-73 sp|Q07DZ1|MET_COLGU Hepatocyte growth factor receptor OS=Colobus ... 272 1e-73 sp|P51813|BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX OS=Ho... 262 1e-73 sp|Q09YL1|MET_ATEGE Hepatocyte growth factor receptor OS=Ateles g... 272 1e-73 sp|Q09YH7|MET_SAIBB Hepatocyte growth factor receptor OS=Saimiri ... 272 1e-73 sp|F4JZW1|PBL13_ARATH Serine/threonine-protein kinase PBL13 OS=Ar... 257 1e-73 sp|P34152|FAK1_MOUSE Focal adhesion kinase 1 OS=Mus musculus OX=1... 269 1e-73 sp|Q07DV8|MET_AOTNA Hepatocyte growth factor receptor OS=Aotus na... 272 1e-73 sp|Q2IBG7|MET_EULMM Hepatocyte growth factor receptor OS=Eulemur ... 272 1e-73 sp|Q54TA1|DRKC_DICDI Probable serine/threonine-protein kinase drk... 264 1e-73 sp|A0M8R7|MET_PAPAN Hepatocyte growth factor receptor OS=Papio an... 272 1e-73 sp|Q1PE89|PBL24_ARATH Probable serine/threonine-protein kinase PB... 253 1e-73 sp|Q07E48|MET_DASNO Hepatocyte growth factor receptor OS=Dasypus ... 272 1e-73 sp|O35346|FAK1_RAT Focal adhesion kinase 1 OS=Rattus norvegicus O... 269 1e-73 sp|Q2IBA6|MET_CHLAE Hepatocyte growth factor receptor OS=Chloroce... 272 1e-73 sp|O49840|PBL3_ARATH Probable serine/threonine-protein kinase PBL... 254 1e-73 sp|Q09YK0|MET_MUNMU Hepatocyte growth factor receptor OS=Muntiacu... 272 2e-73 sp|Q60750|EPHA1_MOUSE Ephrin type-A receptor 1 OS=Mus musculus OX... 268 2e-73 sp|Q00PJ8|MET_ATEAB Hepatocyte growth factor receptor OS=Atelerix... 271 2e-73 sp|Q09147|FGFR2_DROME Fibroblast growth factor receptor homolog 2... 269 2e-73 sp|Q62838|MUSK_RAT Muscle, skeletal receptor tyrosine protein kin... 265 2e-73 sp|Q8GYA4|CRK10_ARATH Cysteine-rich receptor-like protein kinase ... 261 2e-73 sp|Q9M0X5|CRK25_ARATH Cysteine-rich receptor-like protein kinase ... 261 3e-73 sp|Q07E24|MET_MUSPF Hepatocyte growth factor receptor OS=Mustela ... 271 3e-73 sp|Q9ZQ31|STY13_ARATH Serine/threonine-protein kinase STY13 OS=Ar... 253 3e-73 sp|Q75ZY9|MET_CANLF Hepatocyte growth factor receptor OS=Canis lu... 271 3e-73 sp|O49564|CRK27_ARATH Cysteine-rich receptor-like protein kinase ... 260 3e-73 sp|Q2QLA9|MET_HORSE Hepatocyte growth factor receptor OS=Equus ca... 271 3e-73 sp|Q54RB7|SHKA_DICDI Dual specificity protein kinase shkA OS=Dict... 256 4e-73 sp|F4JEQ2|PBL23_ARATH Probable serine/threonine-protein kinase PB... 251 4e-73 sp|Q769I5|MET_BOVIN Hepatocyte growth factor receptor OS=Bos taur... 271 4e-73 sp|Q2QLE0|MET_PIG Hepatocyte growth factor receptor OS=Sus scrofa... 270 4e-73 sp|Q09YI9|MET_SHEEP Hepatocyte growth factor receptor OS=Ovis ari... 270 5e-73 sp|O49839|PBL2_ARATH Probable serine/threonine-protein kinase PBL... 253 5e-73 sp|Q07E37|MET_NEONE Hepatocyte growth factor receptor OS=Neofelis... 270 5e-73 sp|A0M8S8|MET_FELCA Hepatocyte growth factor receptor OS=Felis ca... 270 5e-73 sp|A1X150|MET_ECHTE Hepatocyte growth factor receptor OS=Echinops... 270 5e-73 sp|Q61006|MUSK_MOUSE Muscle, skeletal receptor tyrosine-protein k... 264 6e-73 sp|Q05688|IGF1R_BOVIN Insulin-like growth factor 1 receptor (Frag... 259 6e-73 sp|Q9FGB1|CBC2_ARATH Serine/threonine-protein kinase 52 OS=Arabid... 251 6e-73 sp|Q14289|FAK2_HUMAN Protein-tyrosine kinase 2-beta OS=Homo sapie... 266 6e-73 sp|Q108U6|MET_LOXAF Hepatocyte growth factor receptor OS=Loxodont... 270 7e-73 sp|Q8GWJ7|CRK19_ARATH Cysteine-rich receptor-like protein kinase ... 259 7e-73 sp|Q9SSA4|CBC1_ARATH Serine/threonine-protein kinase 54 OS=Arabid... 251 8e-73 sp|Q62371|DDR2_MOUSE Discoidin domain-containing receptor 2 OS=Mu... 263 8e-73 sp|Q9SYM9|Y1853_ARATH Receptor-like serine/threonine-protein kina... 249 8e-73 sp|Q9CAH1|Y1725_ARATH Putative receptor-like protein kinase At1g7... 253 9e-73 sp|P97504|BMX_MOUSE Cytoplasmic tyrosine-protein kinase BMX OS=Mu... 258 1e-72 sp|Q07E01|MET_ORNAN Hepatocyte growth factor receptor OS=Ornithor... 269 1e-72 sp|Q06806|TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mu... 267 1e-72 sp|Q9XI87|VIK_ARATH Serine/threonine-protein kinase VIK OS=Arabid... 252 1e-72 sp|Q9LQQ8|PBL5_ARATH Probable serine/threonine-protein kinase PBL... 251 2e-72 sp|F4HQ17|LRL14_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 258 2e-72 sp|Q86AT8|SPKA_DICDI Stress-activated protein kinase alpha OS=Dic... 257 2e-72 sp|Q9ZUF4|RIPK_ARATH Serine/threonine-protein kinase RIPK OS=Arab... 252 2e-72 sp|Q03351|NTRK3_RAT NT-3 growth factor receptor OS=Rattus norvegi... 262 3e-72 sp|P23049|SEA_AVIET Tyrosine-protein kinase transforming protein ... 248 3e-72 sp|Q16832|DDR2_HUMAN Discoidin domain-containing receptor 2 OS=Ho... 262 3e-72 sp|Q26614|FGFR_STRPU Fibroblast growth factor receptor OS=Strongy... 264 4e-72 sp|Q00944|FAK1_CHICK Focal adhesion kinase 1 OS=Gallus gallus OX=... 265 4e-72 sp|O81906|B120_ARATH G-type lectin S-receptor-like serine/threoni... 261 4e-72 sp|Q8H1E3|PBL17_ARATH Probable serine/threonine-protein kinase PB... 250 5e-72 sp|P35590|TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 OS=Ho... 265 5e-72 sp|Q95YD4|KIN32_CAEEL Inactive tyrosine-protein kinase kin-32 OS=... 261 5e-72 sp|O65479|CRK20_ARATH Putative cysteine-rich receptor-like protei... 257 7e-72 sp|Q06805|TIE1_BOVIN Tyrosine-protein kinase receptor Tie-1 OS=Bo... 265 7e-72 sp|Q9SYA0|Y1150_ARATH G-type lectin S-receptor-like serine/threon... 260 7e-72 sp|P42687|SPK1_GIRTI Tyrosine-protein kinase SPK-1 OS=Girardia ti... 252 7e-72 sp|P97523|MET_RAT Hepatocyte growth factor receptor OS=Rattus nor... 266 8e-72 sp|Q91738|FAK1_XENLA Focal adhesion kinase 1 OS=Xenopus laevis OX... 264 8e-72 sp|F1N9Y5|KSYK_CHICK Tyrosine-protein kinase SYK OS=Gallus gallus... 255 8e-72 sp|Q3U1V8|M3K9_MOUSE Mitogen-activated protein kinase kinase kina... 264 9e-72 sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kin... 260 9e-72 sp|Q8MY86|FGFR1_DUGJA Fibroblast growth factor receptor 1 OS=Duge... 260 9e-72 sp|Q61527|ERBB4_MOUSE Receptor tyrosine-protein kinase erbB-4 OS=... 266 9e-72 sp|Q05609|CTR1_ARATH Serine/threonine-protein kinase CTR1 OS=Arab... 260 1e-71 sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kinas... 260 1e-71 sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase kin... 260 1e-71 sp|Q9SIB6|PBL6_ARATH Probable serine/threonine-protein kinase PBL... 249 1e-71 sp|Q7T6X2|YR826_MIMIV Putative serine/threonine-protein kinase/re... 266 1e-71 sp|Q78DX7|ROS1_MOUSE Proto-oncogene tyrosine-protein kinase ROS O... 267 1e-71 sp|F4JPX3|PBL20_ARATH Probable serine/threonine-protein kinase PB... 247 2e-71 sp|Q3EDL4|Y1154_ARATH Probable serine/threonine-protein kinase At... 250 2e-71 sp|Q93YN1|CRPK1_ARATH Cold-responsive protein kinase 1 OS=Arabido... 247 2e-71 sp|Q9LZU4|CRK4_ARATH Cysteine-rich receptor-like protein kinase 4... 256 2e-71 sp|P80192|M3K9_HUMAN Mitogen-activated protein kinase kinase kina... 263 2e-71 sp|Q63132|ROS1_RAT Proto-oncogene tyrosine-protein kinase ROS OS=... 266 2e-71 sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens OX=... 262 2e-71 sp|Q1RMT8|IRAK4_BOVIN Interleukin-1 receptor-associated kinase 4 ... 249 2e-71 sp|Q15303|ERBB4_HUMAN Receptor tyrosine-protein kinase erbB-4 OS=... 265 3e-71 sp|Q9YI66|TYRO3_DANRE Tyrosine-protein kinase receptor TYRO3 OS=D... 259 3e-71 sp|P57097|MERTK_RAT Tyrosine-protein kinase Mer OS=Rattus norvegi... 261 3e-71 sp|O54967|ACK1_MOUSE Activated CDC42 kinase 1 OS=Mus musculus OX=... 261 5e-71 sp|P11273|ERBB_AVIEU Tyrosine-protein kinase transforming protein... 251 5e-71 sp|Q9SYS7|CRK39_ARATH Putative cysteine-rich receptor-like protei... 254 6e-71 sp|Q93105|INSR_AEDAE Insulin-like receptor OS=Aedes aegypti OX=71... 264 7e-71 sp|O64771|Y1148_ARATH G-type lectin S-receptor-like serine/threon... 257 7e-71 sp|Q04912|RON_HUMAN Macrophage-stimulating protein receptor OS=Ho... 263 9e-71 sp|Q9FG33|LRKS5_ARATH Probable L-type lectin-domain containing re... 253 9e-71 sp|Q5U2X5|ACK1_RAT Activated CDC42 kinase 1 OS=Rattus norvegicus ... 260 9e-71 sp|Q8RWW0|ALE2_ARATH Receptor-like serine/threonine-protein kinas... 255 1e-70 sp|P08922|ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS O... 264 1e-70 sp|Q9FM85|PBL16_ARATH Probable serine/threonine-protein kinase PB... 245 1e-70 sp|Q75JK0|ZAK1_DICDI Dual specificity protein kinase zakA OS=Dict... 256 1e-70 sp|Q12866|MERTK_HUMAN Tyrosine-protein kinase Mer OS=Homo sapiens... 260 1e-70 sp|Q54Y55|SHKC_DICDI Dual specificity protein kinase shkC OS=Dict... 249 1e-70 sp|Q9SJG2|Y2296_ARATH Probable receptor-like protein kinase At2g4... 248 1e-70 sp|Q60805|MERTK_MOUSE Tyrosine-protein kinase Mer OS=Mus musculus... 259 1e-70 sp|Q62190|RON_MOUSE Macrophage-stimulating protein receptor OS=Mu... 263 1e-70 sp|D3ZG83|M3K10_RAT Mitogen-activated protein kinase kinase kinas... 259 1e-70 sp|Q17R13|ACK1_BOVIN Activated CDC42 kinase 1 OS=Bos taurus OX=99... 260 1e-70 sp|Q24145|SHARK_DROME Tyrosine-protein kinase Shark OS=Drosophila... 258 1e-70 sp|O73798|IGF1R_XENLA Insulin-like growth factor 1 receptor OS=Xe... 263 1e-70 sp|Q9M8S2|LIPG2_ARATH Receptor-like kinase LIP2 OS=Arabidopsis th... 250 2e-70 sp|Q8MY85|FGFR2_DUGJA Fibroblast growth factor receptor 2 OS=Duge... 258 2e-70 sp|Q66L42|M3K10_MOUSE Mitogen-activated protein kinase kinase kin... 258 2e-70 sp|Q6NKZ9|Y4345_ARATH Probable receptor-like serine/threonine-pro... 246 2e-70 sp|Q9SY89|Y1661_ARATH Putative G-type lectin S-receptor-like seri... 257 2e-70 sp|C0LGD7|Y1684_ARATH Probable LRR receptor-like serine/threonine... 259 2e-70 sp|Q9NWZ3|IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 ... 246 2e-70 sp|Q62956|ERBB4_RAT Receptor tyrosine-protein kinase erbB-4 OS=Ra... 262 2e-70 sp|P13388|XMRK_XIPMA Melanoma receptor tyrosine-protein kinase OS... 261 2e-70 sp|D2IYS2|TORSO_BOMMO Tyrosine-protein kinase receptor torso OS=B... 256 2e-70 sp|Q25410|MIPR_LYMST Putative molluscan insulin-related peptide(s... 263 2e-70 sp|Q9C5S8|CRK5_ARATH Cysteine-rich receptor-like protein kinase 5... 252 3e-70 sp|Q03146|DDR1_MOUSE Epithelial discoidin domain-containing recep... 257 3e-70 sp|Q9SYS3|CRK40_ARATH Cysteine-rich receptor-like protein kinase ... 252 3e-70 sp|P0C5E2|LRL12_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 251 3e-70 sp|Q9FID9|Y5389_ARATH Probable receptor-like protein kinase At5g3... 256 3e-70 sp|H2KZU7|SVH2_CAEEL Tyrosine-protein kinase receptor svh-2 OS=Ca... 259 3e-70 sp|D7UPN3|RLK10_ORYSJ LysM domain receptor-like kinase 10 OS=Oryz... 250 3e-70 sp|Q9Z139|ROR1_MOUSE Inactive tyrosine-protein kinase transmembra... 257 3e-70 sp|P00534|ERBB_ALV Tyrosine-protein kinase transforming protein e... 251 4e-70 sp|O64778|Y1142_ARATH G-type lectin S-receptor-like serine/threon... 255 4e-70 sp|O22040|ANP1_ARATH Mitogen-activated protein kinase kinase kina... 251 4e-70 sp|P06213|INSR_HUMAN Insulin receptor OS=Homo sapiens OX=9606 GN=... 261 4e-70 sp|Q55A09|Y9963_DICDI Probable serine/threonine-protein kinase DD... 261 4e-70 sp|Q02779|M3K10_HUMAN Mitogen-activated protein kinase kinase kin... 257 5e-70 sp|Q7T2V3|M3K10_XENLA Mitogen-activated protein kinase kinase kin... 258 5e-70 sp|Q9SF86|PCRK1_ARATH Serine/threonine-protein kinase PCRK1 OS=Ar... 244 6e-70 sp|O64780|Y1614_ARATH G-type lectin S-receptor-like serine/threon... 254 6e-70 sp|Q22146|FRK1_CAEEL Fer-related kinase 1 OS=Caenorhabditis elega... 243 6e-70 sp|Q9FZ36|M3K2_ARATH Mitogen-activated protein kinase kinase kina... 251 6e-70 sp|A2VDU3|M3K7_BOVIN Mitogen-activated protein kinase kinase kina... 249 6e-70 sp|Q62073|M3K7_MOUSE Mitogen-activated protein kinase kinase kina... 248 7e-70 sp|Q7YR43|DDR1_PANTR Epithelial discoidin domain-containing recep... 256 8e-70 sp|Q08345|DDR1_HUMAN Epithelial discoidin domain-containing recep... 256 8e-70 sp|Q0D5R3|CRK6_ORYSJ Cysteine-rich receptor-like protein kinase 6... 251 8e-70 sp|Q9FFW5|PERK8_ARATH Proline-rich receptor-like protein kinase P... 251 9e-70 sp|Q9XEC6|CRK36_ARATH Cysteine-rich receptor-like protein kinase ... 250 1e-69 sp|O73791|TIE2_DANRE Angiopoietin-1 receptor OS=Danio rerio OX=79... 258 1e-69 sp|P0C8E4|M3K7_RAT Mitogen-activated protein kinase kinase kinase... 249 1e-69 sp|Q5RFL3|M3K7_PONAB Mitogen-activated protein kinase kinase kina... 249 1e-69 sp|O43318|M3K7_HUMAN Mitogen-activated protein kinase kinase kina... 249 1e-69 sp|C0LGE0|Y1765_ARATH Probable LRR receptor-like serine/threonine... 257 1e-69 sp|Q9SR05|ANX1_ARATH Receptor-like protein kinase ANXUR1 OS=Arabi... 254 1e-69 sp|Q98949|TYRO3_CHICK Tyrosine-protein kinase receptor TYRO3 OS=G... 254 1e-69 sp|P08941|ROS1_CHICK Proto-oncogene tyrosine-protein kinase ROS O... 260 2e-69 sp|Q9LRP3|Y3174_ARATH Probable receptor-like protein kinase At3g1... 244 2e-69 sp|Q9ASQ5|CRCK3_ARATH Calmodulin-binding receptor-like cytoplasmi... 245 2e-69 sp|O22042|M3K3_ARATH Mitogen-activated protein kinase kinase kina... 249 2e-69 sp|Q9C6K9|LRL11_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEP... 249 2e-69 sp|O76997|TRK1_LYMST Putative neurotrophin receptor LTRK 1 OS=Lym... 253 2e-69 sp|O64781|Y1639_ARATH G-type lectin S-receptor-like serine/threon... 253 2e-69 sp|O65472|CRK12_ARATH Putative cysteine-rich receptor-like protei... 249 2e-69 sp|Q9LSE1|CDG1_ARATH Serine/threonine-protein kinase CDG1 OS=Arab... 243 2e-69 sp|P08069|IGF1R_HUMAN Insulin-like growth factor 1 receptor OS=Ho... 259 2e-69 sp|Q54VC0|Y9865_DICDI Probable serine/threonine-protein kinase DD... 242 2e-69 sp|P00535|ERBB_AVIER Tyrosine-protein kinase transforming protein... 248 2e-69 sp|Q8LEB6|Y5185_ARATH Probable receptor-like protein kinase At5g1... 244 3e-69 sp|O64784|Y1136_ARATH G-type lectin S-receptor-like serine/threon... 253 3e-69 sp|O81832|Y4729_ARATH G-type lectin S-receptor-like serine/threon... 252 3e-69 sp|Q3E8W4|ANX2_ARATH Receptor-like protein kinase ANXUR2 OS=Arabi... 253 3e-69 sp|Q9FIU5|CRLK1_ARATH Calcium/calmodulin-regulated receptor-like ... 243 3e-69 sp|P24062|IGF1R_RAT Insulin-like growth factor 1 receptor OS=Ratt... 258 3e-69 sp|Q9UM73|ALK_HUMAN ALK tyrosine kinase receptor OS=Homo sapiens ... 259 3e-69 sp|Q6I5Q6|RK185_ORYSJ Receptor-like cytoplasmic kinase 185 OS=Ory... 244 3e-69 sp|Q1PDW3|LIPG1_ARATH Receptor-like kinase LIP1 OS=Arabidopsis th... 248 3e-69 sp|Q9ZR08|Y4230_ARATH G-type lectin S-receptor-like serine/threon... 253 4e-69 sp|Q60751|IGF1R_MOUSE Insulin-like growth factor 1 receptor OS=Mu... 258 4e-69 sp|Q01973|ROR1_HUMAN Inactive tyrosine-protein kinase transmembra... 254 5e-69 sp|O65476|CRK16_ARATH Putative cysteine-rich receptor-like protei... 248 5e-69 sp|Q63474|DDR1_RAT Epithelial discoidin domain-containing recepto... 253 5e-69 sp|Q9NYL2|M3K20_HUMAN Mitogen-activated protein kinase kinase kin... 251 6e-69 sp|Q9LYN8|EMS1_ARATH Leucine-rich repeat receptor protein kinase ... 256 6e-69 sp|Q9ESL4|M3K20_MOUSE Mitogen-activated protein kinase kinase kin... 251 6e-69 sp|Q9FID8|Y5900_ARATH Putative receptor-like protein kinase At5g3... 253 7e-69 sp|C0LGU1|Y5374_ARATH Probable LRR receptor-like serine/threonine... 254 7e-69 sp|O65483|CRK24_ARATH Cysteine-rich receptor-like protein kinase ... 247 8e-69 sp|Q9XEC7|CRK37_ARATH Cysteine-rich receptor-like protein kinase ... 247 8e-69 sp|P97793|ALK_MOUSE ALK tyrosine kinase receptor OS=Mus musculus ... 258 8e-69 sp|C0LGU5|Y5457_ARATH Probable LRR receptor-like serine/threonine... 246 8e-69 sp|Q9CAC3|CRK43_ARATH Cysteine-rich receptor-like protein kinase ... 240 9e-69 sp|P0CY46|EGFR_APIME Epidermal growth factor receptor OS=Apis mel... 256 1e-68 sp|Q54L00|LIMKA_DICDI Probable LIM domain-containing serine/threo... 247 1e-68 sp|Q9ZT07|RKS1_ARATH G-type lectin S-receptor-like serine/threoni... 251 1e-68 sp|P15208|INSR_MOUSE Insulin receptor OS=Mus musculus OX=10090 GN... 256 1e-68 sp|Q9XEC8|CRK38_ARATH Cysteine-rich receptor-like protein kinase ... 247 1e-68 sp|Q9SXB8|Y1133_ARATH G-type lectin S-receptor-like serine/threon... 251 1e-68 sp|Q9M9E0|LRKS1_ARATH L-type lectin-domain containing receptor ki... 247 1e-68 sp|Q9PVZ4|INSR_XENLA Insulin receptor OS=Xenopus laevis OX=8355 G... 256 1e-68 sp|Q9FPR3|EDR1_ARATH Serine/threonine-protein kinase EDR1 OS=Arab... 253 1e-68 sp|Q25197|HTK7_HYDVU Putative insulin-like peptide receptor OS=Hy... 257 1e-68 sp|P0DV84|ALK_CANLF ALK tyrosine kinase receptor OS=Canis lupus f... 257 1e-68 sp|O64776|Y1144_ARATH G-type lectin S-receptor-like serine/threon... 250 2e-68 sp|A0JM20|TYRO3_XENTR Tyrosine-protein kinase receptor TYRO3 OS=X... 251 2e-68 sp|Q10656|EGL15_CAEEL Myoblast growth factor receptor egl-15 OS=C... 254 2e-68 sp|Q0D5R2|CRK10_ORYSJ Cysteine-rich receptor-like protein kinase ... 246 2e-68 sp|P15127|INSR_RAT Insulin receptor OS=Rattus norvegicus OX=10116... 256 2e-68 sp|Q95ZV7|DDRB_CAEEL Discoidin domain-containing receptor tyrosin... 249 2e-68 sp|O65482|CRK23_ARATH Putative cysteine-rich receptor-like protei... 250 2e-68 sp|Q8W4G6|CRK15_ARATH Cysteine-rich receptor-like protein kinase ... 246 2e-68 sp|Q41328|PTI1_SOLLC Pto-interacting protein 1 OS=Solanum lycoper... 237 2e-68 sp|O65468|CRK8_ARATH Cysteine-rich receptor-like protein kinase 8... 246 3e-68 sp|Q9SA25|WAKLG_ARATH Wall-associated receptor kinase-like 8 OS=A... 247 3e-68 sp|P13368|7LESS_DROME Protein sevenless OS=Drosophila melanogaste... 256 4e-68 sp|C0LGG8|Y5343_ARATH Probable LRR receptor-like serine/threonine... 253 4e-68 sp|P30530|UFO_HUMAN Tyrosine-protein kinase receptor UFO OS=Homo ... 250 5e-68 sp|P08923|LTK_MOUSE Leukocyte tyrosine kinase receptor OS=Mus mus... 250 5e-68 sp|O64842|PBL12_ARATH Probable serine/threonine-protein kinase PB... 238 6e-68 sp|A0A0P0XII1|CERK1_ORYSJ Chitin elicitor receptor kinase 1 OS=Or... 244 7e-68 sp|Q54XQ2|RCKA_DICDI RGS domain-containing serine/threonine-prote... 253 7e-68 sp|O64783|Y1137_ARATH G-type lectin S-receptor-like serine/threon... 248 8e-68 sp|Q9LDQ3|CRK34_ARATH Cysteine-rich receptor-like protein kinase ... 244 1e-67 sp|Q9ASQ6|Y1972_ARATH Probable LRR receptor-like serine/threonine... 251 1e-67 sp|O61460|VAB1_CAEEL Ephrin receptor 1 OS=Caenorhabditis elegans ... 252 1e-67 sp|Q8QFP9|TYRO3_XENLA Tyrosine-protein kinase receptor TYRO3 OS=X... 249 1e-67 sp|Q54PX0|Y4251_DICDI Probable serine/threonine-protein kinase DD... 239 1e-67 sp|Q9S972|SD16_ARATH Receptor-like serine/threonine-protein kinas... 248 2e-67 sp|P29376|LTK_HUMAN Leukocyte tyrosine kinase receptor OS=Homo sa... 248 2e-67 sp|F8W3R9|ALK_DANRE ALK tyrosine kinase receptor OS=Danio rerio O... 253 2e-67 sp|O61122|SVKA_DICDI Serine/threonine-protein kinase svkA OS=Dict... 238 2e-67 sp|Q8VYA3|WAKLJ_ARATH Wall-associated receptor kinase-like 10 OS=... 246 2e-67 sp|C0LGG7|Y1534_ARATH Probable LRR receptor-like serine/threonine... 249 2e-67 sp|P20806|7LESS_DROVI Protein sevenless OS=Drosophila virilis OX=... 254 2e-67 sp|F4HRJ4|M3K3A_ARATH Mitogen-activated protein kinase kinase kin... 242 2e-67 sp|Q00993|UFO_MOUSE Tyrosine-protein kinase receptor UFO OS=Mus m... 248 2e-67 sp|P55146|TYRO3_RAT Tyrosine-protein kinase receptor TYRO3 OS=Rat... 248 2e-67 sp|Q9SXB4|Y1130_ARATH G-type lectin S-receptor-like serine/threon... 247 2e-67 sp|Q8L710|CRK17_ARATH Cysteine-rich receptor-like protein kinase ... 244 2e-67 sp|C0LGF4|FEI1_ARATH LRR receptor-like serine/threonine-protein k... 241 2e-67 sp|C0LGG9|Y5344_ARATH Probable LRR receptor-like serine/threonine... 250 2e-67 sp|Q86IX1|DST1_DICDI Serine/threonine-protein kinase dst1 OS=Dict... 245 3e-67 sp|O23082|CRK44_ARATH Cysteine-rich receptor-like protein kinase ... 235 3e-67 sp|O64793|Y1675_ARATH G-type lectin S-receptor-like serine/threon... 247 3e-67 sp|Q9LDN1|CRK33_ARATH Putative cysteine-rich receptor-like protei... 243 3e-67 sp|Q9C5S9|CRK6_ARATH Cysteine-rich receptor-like protein kinase 6... 243 3e-67 sp|P14617|INSRR_CAVPO Insulin receptor-related protein OS=Cavia p... 252 3e-67 sp|Q8RX80|CRK18_ARATH Cysteine-rich receptor-like protein kinase ... 243 3e-67 sp|Q9VZI2|ACK_DROME Activated Cdc42 kinase Ack OS=Drosophila mela... 250 3e-67 sp|P55144|TYRO3_MOUSE Tyrosine-protein kinase receptor TYRO3 OS=M... 248 3e-67 sp|Q9T058|Y4119_ARATH G-type lectin S-receptor-like serine/threon... 247 3e-67 sp|Q06418|TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3 OS=H... 248 3e-67 sp|C0LGQ7|Y4245_ARATH Probable LRR receptor-like serine/threonine... 248 3e-67 sp|Q9LZF8|PCRK2_ARATH Serine/threonine-protein kinase PCRK2 OS=Ar... 236 3e-67 sp|Q9T0J1|CRK26_ARATH Cysteine-rich receptor-like protein kinase ... 243 4e-67 sp|Q9LDM5|CRK31_ARATH Putative cysteine-rich receptor-like protei... 243 4e-67 sp|Q9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 OS=Homo ... 236 4e-67 sp|Q39086|SD17_ARATH Receptor-like serine/threonine-protein kinas... 246 4e-67 sp|P18160|SPLA_DICDI Dual specificity protein kinase splA OS=Dict... 253 4e-67 sp|H2L099|GCK1_CAEEL Germinal center kinase 1 OS=Caenorhabditis e... 242 5e-67 sp|Q9SN43|CIPKC_ARATH CBL-interacting serine/threonine-protein ki... 238 5e-67 sp|Q99KH8|STK24_MOUSE Serine/threonine-protein kinase 24 OS=Mus m... 236 5e-67 sp|Q9LDS6|CRK32_ARATH Putative cysteine-rich receptor-like protei... 242 6e-67 sp|Q8R4K2|IRAK4_MOUSE Interleukin-1 receptor-associated kinase 4 ... 236 6e-67 sp|Q54IP4|SHKB_DICDI Dual specificity protein kinase shkB OS=Dict... 242 6e-67 sp|Q8RZV7|MSP1_ORYSJ Leucine-rich repeat receptor protein kinase ... 251 6e-67 sp|Q9FN92|Y5597_ARATH Probable receptor-like protein kinase At5g5... 246 6e-67 sp|O81833|SD11_ARATH G-type lectin S-receptor-like serine/threoni... 246 6e-67 sp|Q54TH6|Y9863_DICDI Probable serine/threonine-protein kinase DD... 241 6e-67 sp|Q9LX66|HERK_ARATH Receptor-like protein kinase HERK 1 OS=Arabi... 246 7e-67 sp|C0LGT5|Y5169_ARATH Probable LRR receptor-like serine/threonine... 246 7e-67 sp|A7J1T2|M313A_XENLA Mitogen-activated protein kinase kinase kin... 248 8e-67 sp|Q5Z6X0|CIPKP_ORYSJ CBL-interacting protein kinase 25 OS=Oryza ... 238 8e-67 sp|O65405|CRK28_ARATH Cysteine-rich receptor-like protein kinase ... 243 8e-67 sp|Q6Z4U4|BAK1_ORYSJ LRR receptor kinase BAK1 OS=Oryza sativa sub... 241 8e-67 sp|B8BB68|BAK1_ORYSI LRR receptor kinase BAK1 OS=Oryza sativa sub... 241 8e-67 sp|O64777|Y1643_ARATH G-type lectin S-receptor-like serine/threon... 245 8e-67 sp|O24527|SIK1_ARATH Serine/threonine-protein kinase 1 OS=Arabido... 246 9e-67 sp|Q94F62|BAK1_ARATH BRASSINOSTEROID INSENSITIVE 1-associated rec... 241 9e-67 sp|Q9CAL8|PEK13_ARATH Proline-rich receptor-like protein kinase P... 243 9e-67 sp|Q8H199|CRK14_ARATH Cysteine-rich receptor-like protein kinase ... 241 1e-66 sp|Q7X8C5|WAKLB_ARATH Wall-associated receptor kinase-like 2 OS=A... 244 1e-66 sp|Q55EC7|GEFX_DICDI RasGEF domain-containing serine/threonine-pr... 247 1e-66 sp|Q9SIT1|TMK3_ARATH Receptor-like kinase TMK3 OS=Arabidopsis tha... 247 1e-66 sp|Q8L4H4|NORK_MEDTR Nodulation receptor kinase OS=Medicago trunc... 247 1e-66 sp|B0LT89|STK24_RAT Serine/threonine-protein kinase 24 OS=Rattus ... 235 1e-66 sp|Q8L7G3|CRK7_ARATH Cysteine-rich receptor-like protein kinase 7... 241 1e-66 sp|P48025|KSYK_MOUSE Tyrosine-protein kinase SYK OS=Mus musculus ... 240 1e-66 sp|Q9M2S4|LRKS4_ARATH L-type lectin-domain containing receptor ki... 242 1e-66 sp|O64770|Y1649_ARATH G-type lectin S-receptor-like serine/threon... 244 1e-66 sp|Q9SGY7|PEK11_ARATH Putative proline-rich receptor-like protein... 243 1e-66 sp|Q3E9X6|CRK21_ARATH Cysteine-rich receptor-like protein kinase ... 242 2e-66 sp|Q9LW83|CE101_ARATH G-type lectin S-receptor-like serine/threon... 245 2e-66 sp|Q8S9L6|CRK29_ARATH Cysteine-rich receptor-like protein kinase ... 241 2e-66 sp|O64768|RAF24_ARATH RAF-like serine/threonine-protein kinase 24... 249 2e-66 sp|O49339|PTI12_ARATH PTI1-like tyrosine-protein kinase 2 OS=Arab... 232 2e-66 sp|Q9ZP16|CRK11_ARATH Cysteine-rich receptor-like protein kinase ... 241 2e-66 sp|Q9SY95|Y1155_ARATH G-type lectin S-receptor-like serine/threon... 244 2e-66 sp|G5EGK5|CAM1_CAEEL Tyrosine-protein kinase receptor cam-1 OS=Ca... 246 2e-66 sp|Q9I7F7|ACKL_DROME Activated Cdc42 kinase-like OS=Drosophila me... 249 2e-66 sp|P53668|LIMK1_MOUSE LIM domain kinase 1 OS=Mus musculus OX=1009... 240 2e-66 sp|Q54RR9|Y9844_DICDI Probable serine/threonine-protein kinase DD... 250 2e-66 sp|Q8LKZ1|NORK_PEA Nodulation receptor kinase OS=Pisum sativum OX... 246 2e-66 sp|Q0WNY5|WAKLN_ARATH Wall-associated receptor kinase-like 18 OS=... 243 3e-66 sp|P14616|INSRR_HUMAN Insulin receptor-related protein OS=Homo sa... 249 3e-66 sp|F1QVU0|LTK_DANRE Tyrosine-protein kinase receptor OS=Danio rer... 249 3e-66 sp|C0LGL9|FEI2_ARATH LRR receptor-like serine/threonine-protein k... 238 3e-66 sp|A7J1T0|M313B_XENLA Mitogen-activated protein kinase kinase kin... 246 3e-66 sp|C0LGL4|Y2289_ARATH Probable LRR receptor-like serine/threonine... 244 4e-66 sp|O59790|ARK1_SCHPO Serine/threonine-protein kinase ark1 OS=Schi... 231 4e-66 sp|O61125|STK4_DICDI Serine/threonine-protein kinase 4 homolog A ... 234 4e-66 sp|Q94AG2|SERK1_ARATH Somatic embryogenesis receptor kinase 1 OS=... 239 4e-66 sp|P43405|KSYK_HUMAN Tyrosine-protein kinase SYK OS=Homo sapiens ... 239 4e-66 sp|P55245|EGFR_MACMU Epidermal growth factor receptor OS=Macaca m... 248 4e-66 sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sap... 248 4e-66 sp|Q9WTL4|INSRR_MOUSE Insulin receptor-related protein OS=Mus mus... 248 4e-66 sp|P70424|ERBB2_MOUSE Receptor tyrosine-protein kinase erbB-2 OS=... 248 4e-66 sp|C0LGV0|Y5487_ARATH Probable LRR receptor-like serine/threonine... 244 5e-66 sp|Q01279|EGFR_MOUSE Epidermal growth factor receptor OS=Mus musc... 248 5e-66 sp|Q7XV05|SERK2_ORYSJ LRR receptor kinase SERK2 OS=Oryza sativa s... 239 5e-66 sp|Q95UN8|M3KSL_DROME Mitogen-activated protein kinase kinase kin... 247 5e-66 sp|A9SY39|M3K1A_PHYPA Mitogen-activated protein kinase kinase kin... 242 5e-66 sp|P10533|RMIL_AVII1 Serine/threonine-protein kinase-transforming... 231 6e-66 sp|Q93ZS4|NIK3_ARATH Protein NSP-INTERACTING KINASE 3 OS=Arabidop... 239 6e-66 sp|Q9LXA5|LRK91_ARATH L-type lectin-domain containing receptor ki... 239 6e-66 sp|Q9LUT0|CARK1_ARATH Receptor-like cytoplasmic kinase 1 OS=Arabi... 230 6e-66 sp|Q6ZCZ2|BRL3_ORYSJ Brassinosteroid LRR receptor kinase BRL3 OS=... 247 6e-66 sp|Q60700|M3K12_MOUSE Mitogen-activated protein kinase kinase kin... 244 7e-66 sp|P53669|LIMK1_RAT LIM domain kinase 1 OS=Rattus norvegicus OX=1... 239 7e-66 sp|Q64716|INSRR_RAT Insulin receptor-related protein OS=Rattus no... 248 7e-66 sp|Q8BKG3|PTK7_MOUSE Inactive tyrosine-protein kinase 7 OS=Mus mu... 246 7e-66 sp|P00532|RAF_MSV36 Serine/threonine-protein kinase-transforming ... 229 8e-66 sp|Q23915|KINX_DICDI Probable serine/threonine-protein kinase kin... 246 8e-66 sp|P09208|INSR_DROME Insulin-like receptor OS=Drosophila melanoga... 249 8e-66 sp|Q12852|M3K12_HUMAN Mitogen-activated protein kinase kinase kin... 243 9e-66 sp|P06494|ERBB2_RAT Receptor tyrosine-protein kinase erbB-2 OS=Ra... 247 9e-66 sp|Q9ES74|NEK7_MOUSE Serine/threonine-protein kinase Nek7 OS=Mus ... 228 9e-66 sp|Q9LFH9|LRK81_ARATH L-type lectin-domain containing receptor ki... 240 9e-66 sp|Q9FJ55|CIPKJ_ARATH CBL-interacting serine/threonine-protein ki... 234 9e-66 sp|Q9V6K3|ROR2_DROME Tyrosine-protein kinase transmembrane recept... 240 1e-65 sp|Q60553|ERBB2_MESAU Receptor tyrosine-protein kinase erbB-2 OS=... 247 1e-65 sp|Q69JN6|BRL1_ORYSJ Brassinosteroid LRR receptor kinase BRL1 OS=... 247 1e-65 sp|O02466|ILPR_BRALA Insulin-like peptide receptor OS=Branchiosto... 247 1e-65 sp|Q9SXB5|Y1135_ARATH G-type lectin S-receptor-like serine/threon... 242 1e-65 sp|Q40541|NPK1_TOBAC Mitogen-activated protein kinase kinase kina... 239 1e-65 sp|Q9S9M3|WAKLC_ARATH Wall-associated receptor kinase-like 3 OS=A... 240 1e-65 sp|Q63796|M3K12_RAT Mitogen-activated protein kinase kinase kinas... 243 1e-65 sp|Q8TDX7|NEK7_HUMAN Serine/threonine-protein kinase Nek7 OS=Homo... 227 1e-65 sp|O65440|BAME3_ARATH Leucine-rich repeat receptor-like serine/th... 244 1e-65 sp|O22476|BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 OS=Ara... 246 1e-65 sp|D3ZBE5|NEK7_RAT Serine/threonine-protein kinase Nek7 OS=Rattus... 227 1e-65 sp|Q5MD89|VGFR3_DANRE Vascular endothelial growth factor receptor... 247 1e-65 sp|Q99JT2|STK26_MOUSE Serine/threonine-protein kinase 26 OS=Mus m... 231 1e-65 sp|Q86HG9|Y9871_DICDI Probable serine/threonine-protein kinase DD... 245 1e-65 sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens OX=9606... 238 1e-65 sp|P04626|ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 OS=... 247 1e-65 sp|Q9ZVR7|PSKR1_ARATH Phytosulfokine receptor 1 OS=Arabidopsis th... 244 1e-65 sp|P0CD62|LIMKB_DICDI Probable LIM domain-containing serine/threo... 244 1e-65 sp|Q8LPB4|PSKR1_DAUCA Phytosulfokine receptor 1 OS=Daucus carota ... 244 1e-65 sp|Q8BYG9|EPHAA_MOUSE Ephrin type-A receptor 10 OS=Mus musculus O... 244 1e-65 sp|Q96285|LRK55_ARATH L-type lectin-domain containing receptor ki... 238 1e-65 sp|Q7X996|CIPK2_ORYSJ CBL-interacting protein kinase 2 OS=Oryza s... 232 1e-65 sp|Q0WVM4|Y2239_ARATH Probable LRR receptor-like serine/threonine... 238 1e-65 sp|Q9ZRF9|RPK1_ARATH Probable LRR receptor-like serine/threonine-... 235 2e-65 sp|A0A2R6XIK6|PRAF_MARPO RAF-like serine/threonine-protein kinase... 247 2e-65 sp|Q8H1G6|PTI11_ARATH PTI1-like tyrosine-protein kinase 1 OS=Arab... 229 2e-65 sp|Q9FJ54|CIPKK_ARATH CBL-interacting serine/threonine-protein ki... 232 2e-65 sp|Q9FN94|RLK0_ARATH Receptor-like protein kinase At5g59670 OS=Ar... 242 2e-65 sp|Q9SA72|Y1357_ARATH Probable receptor-like protein kinase At1g3... 242 2e-65 sp|Q9P289|STK26_HUMAN Serine/threonine-protein kinase 26 OS=Homo ... 231 2e-65 sp|F4IB81|LYK3_ARATH LysM domain receptor-like kinase 3 OS=Arabid... 238 2e-65 sp|O04534|LRK51_ARATH Putative L-type lectin-domain containing re... 238 2e-65 sp|O22932|CIPKB_ARATH CBL-interacting serine/threonine-protein ki... 231 2e-65 sp|Q9FHG4|LRKS7_ARATH Probable L-type lectin-domain containing re... 238 2e-65 sp|Q8VYY5|NCRK_ARATH Receptor-like serine/threonine-protein kinas... 235 2e-65 sp|Q64725|KSYK_RAT Tyrosine-protein kinase SYK OS=Rattus norvegic... 237 2e-65 sp|Q54U31|SHKD_DICDI Dual specificity protein kinase shkD OS=Dict... 239 3e-65 sp|Q3SWY6|STK25_BOVIN Serine/threonine-protein kinase 25 OS=Bos t... 231 3e-65 sp|Q9SZD5|LRK59_ARATH L-type lectin-domain containing receptor ki... 238 3e-65 sp|C0LGQ5|GSO1_ARATH LRR receptor-like serine/threonine-protein k... 246 3e-65 sp|Q1HKZ5|M3K13_MOUSE Mitogen-activated protein kinase kinase kin... 243 3e-65 sp|Q9LDT0|CRK30_ARATH Putative cysteine-rich receptor-like protei... 238 3e-65 sp|Q9Z2W1|STK25_MOUSE Serine/threonine-protein kinase 25 OS=Mus m... 231 3e-65 sp|Q9M092|WAKLM_ARATH Wall-associated receptor kinase-like 17 OS=... 240 3e-65 sp|Q8W1D5|CIPKP_ARATH CBL-interacting serine/threonine-protein ki... 233 3e-65 sp|Q9XIC7|SERK2_ARATH Somatic embryogenesis receptor kinase 2 OS=... 236 3e-65 sp|Q9FXF2|RKF1_ARATH Probable LRR receptor-like serine/threonine-... 243 3e-65 sp|P00531|MIL_AVIMH Serine/threonine-protein kinase-transforming ... 229 3e-65 sp|Q942F3|BRI1_ORYSJ Brassinosteroid LRR receptor kinase BRI1 OS=... 244 4e-65 sp|Q9LN59|WAKLK_ARATH Putative wall-associated receptor kinase-li... 240 4e-65 sp|P23437|CDK2_XENLA Cyclin-dependent kinase 2 OS=Xenopus laevis ... 226 4e-65 sp|Q8VDG6|M3K21_MOUSE Mitogen-activated protein kinase kinase kin... 243 4e-65 sp|Q5JZY3|EPHAA_HUMAN Ephrin type-A receptor 10 OS=Homo sapiens O... 243 4e-65 sp|O00506|STK25_HUMAN Serine/threonine-protein kinase 25 OS=Homo ... 230 4e-65 sp|Q7G768|BRL2_ORYSJ Brassinosteroid LRR receptor kinase BRL2 OS=... 244 5e-65 sp|Q9M1Z9|LRK58_ARATH Putative L-type lectin-domain containing re... 236 5e-65 sp|Q00655|KSYK_PIG Tyrosine-protein kinase SYK OS=Sus scrofa OX=9... 236 5e-65 sp|Q9S9M2|WAKLD_ARATH Wall-associated receptor kinase-like 4 OS=A... 239 5e-65 sp|Q54R58|YTYK2_DICDI Probable tyrosine-protein kinase DDB_G02833... 241 6e-65 sp|C0LGN2|Y3148_ARATH Probable leucine-rich repeat receptor-like ... 243 6e-65 sp|Q9SKG5|SERK4_ARATH Somatic embryogenesis receptor kinase 4 OS=... 235 7e-65 sp|Q5E9L6|STK4_BOVIN Serine/threonine-protein kinase 4 OS=Bos tau... 231 7e-65 sp|O18735|ERBB2_CANLF Receptor tyrosine-protein kinase erbB-2 OS=... 244 7e-65 sp|O80623|Y2393_ARATH Probable receptor-like protein kinase At2g3... 239 7e-65 sp|P27966|RMIL_AVEVR Serine/threonine-protein kinase-transforming... 230 7e-65 sp|Q39202|RLK1_ARATH G-type lectin S-receptor-like serine/threoni... 240 8e-65 sp|P43298|TMK1_ARATH Receptor protein kinase TMK1 OS=Arabidopsis ... 241 8e-65 sp|C0LGG6|Y5189_ARATH Probable LRR receptor-like protein kinase A... 240 8e-65 sp|Q9S9M5|WAKLA_ARATH Wall-associated receptor kinase-like 1 OS=A... 238 8e-65 sp|Q9LFV3|CRLK2_ARATH Calcium/calmodulin-regulated receptor-like ... 229 9e-65 sp|Q9LEU7|CIPK5_ARATH CBL-interacting serine/threonine-protein ki... 230 9e-65 sp|A8R7E6|CERK1_ARATH Chitin elicitor receptor kinase 1 OS=Arabid... 235 9e-65 sp|Q9FX99|Y1497_ARATH Probable receptor-like protein kinase At1g4... 236 9e-65 sp|O80719|Y2706_ARATH Probable receptor-like protein kinase At2g4... 227 9e-65 sp|Q1PEM5|PERK3_ARATH Proline-rich receptor-like protein kinase P... 232 9e-65 sp|Q86AE1|Y9853_DICDI Probable serine/threonine-protein kinase DD... 232 1e-64 sp|O43283|M3K13_HUMAN Mitogen-activated protein kinase kinase kin... 241 1e-64 sp|Q9LIG2|RLK6_ARATH Receptor-like protein kinase At3g21340 OS=Ar... 240 1e-64 sp|Q13308|PTK7_HUMAN Inactive tyrosine-protein kinase 7 OS=Homo s... 243 1e-64 sp|Q9JI11|STK4_MOUSE Serine/threonine-protein kinase 4 OS=Mus mus... 231 1e-64 sp|Q9FZB8|Y5181_ARATH Probable LRR receptor-like serine/threonine... 240 1e-64 sp|P04412|EGFR_DROME Epidermal growth factor receptor OS=Drosophi... 244 1e-64 sp|Q13043|STK4_HUMAN Serine/threonine-protein kinase 4 OS=Homo sa... 231 1e-64 sp|Q9LV48|PERK1_ARATH Proline-rich receptor-like protein kinase P... 235 1e-64 sp|A4K2Y1|STK4_CHLAE Serine/threonine-protein kinase 4 OS=Chloroc... 231 1e-64 sp|A4K2T0|STK4_MACMU Serine/threonine-protein kinase 4 OS=Macaca ... 231 1e-64 sp|Q8VYT3|Y4052_ARATH Probable LRR receptor-like serine/threonine... 235 1e-64 sp|A4K2M3|STK4_PAPAN Serine/threonine-protein kinase 4 OS=Papio a... 231 1e-64 sp|Q9SX31|PERK9_ARATH Proline-rich receptor-like protein kinase P... 236 1e-64 sp|O23081|CRK41_ARATH Cysteine-rich receptor-like protein kinase ... 236 1e-64 sp|Q9ZUE0|PEK12_ARATH Proline-rich receptor-like protein kinase P... 237 1e-64 sp|Q8RY17|WAKLI_ARATH Wall-associated receptor kinase-like 22 OS=... 237 1e-64 sp|Q9FNE1|CRK42_ARATH Cysteine-rich receptor-like protein kinase ... 235 1e-64 sp|Q8RY67|WAKLO_ARATH Wall-associated receptor kinase-like 14 OS=... 236 2e-64 sp|P83104|M3K7L_DROME Putative mitogen-activated protein kinase k... 227 2e-64 sp|Q00526|CDK3_HUMAN Cyclin-dependent kinase 3 OS=Homo sapiens OX... 224 2e-64 sp|Q852Q0|OSK3_ORYSJ Serine/threonine protein kinase OSK3 OS=Oryz... 231 2e-64 sp|A2XFF4|OSK3_ORYSI Serine/threonine protein kinase OSK3 OS=Oryz... 231 2e-64 sp|P18161|SPLB_DICDI Dual specificity protein kinase splB OS=Dict... 243 2e-64 sp|P05625|RAF1_CHICK RAF proto-oncogene serine/threonine-protein ... 235 2e-64 sp|O81905|SD18_ARATH Receptor-like serine/threonine-protein kinas... 239 2e-64 sp|Q9C821|PEK15_ARATH Proline-rich receptor-like protein kinase P... 231 2e-64 sp|Q54XX5|Y9849_DICDI Probable serine/threonine-protein kinase DD... 239 2e-64 sp|O81069|Y2899_ARATH Probable leucine-rich repeat receptor-like ... 239 2e-64 sp|C0LGI2|Y1677_ARATH Probable LRR receptor-like serine/threonine... 240 2e-64 sp|O64782|SD129_ARATH G-type lectin S-receptor-like serine/threon... 238 2e-64 sp|Q8T2I8|SEPA_DICDI Serine/threonine-protein kinase sepA OS=Dict... 242 2e-64 sp|Q9FZB1|Y5188_ARATH Probable LRR receptor-like serine/threonine... 239 2e-64 sp|Q5E9Y0|CDK2_BOVIN Cyclin-dependent kinase 2 OS=Bos taurus OX=9... 223 2e-64 sp|Q6H7U5|CIPKQ_ORYSJ CBL-interacting protein kinase 26 OS=Oryza ... 230 2e-64 Sequences not found previously or not previously below threshold: >sp|P29597|TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 OS=Homo sapiens OX=9606 GN=TYK2 PE=1 SV=3 Length=1187 Score = 1630 bits (4220), Expect = 0.0, Method: Composition-based stats. Identities = 1187/1187 (100%), Positives = 1187/1187 (100%), Gaps = 0/1187 (0%) Query 1 MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI 60 MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI Sbjct 1 MPLRHWGMARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHI 60 Query 61 AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREP 120 AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREP Sbjct 61 AHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREP 120 Query 121 AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFK 180 AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFK Sbjct 121 AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFK 180 Query 181 NESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRR 240 NESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRR Sbjct 181 NESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRR 240 Query 241 FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP 300 FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP Sbjct 241 FLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAP 300 Query 301 TDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHK 360 TDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHK Sbjct 301 TDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHK 360 Query 361 AVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLV 420 AVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLV Sbjct 361 AVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLV 420 Query 421 DGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP 480 DGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP Sbjct 421 DGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP 480 Query 481 YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA 540 YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA Sbjct 481 YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA 540 Query 541 GDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTR 600 GDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTR Sbjct 541 GDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTR 600 Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS Sbjct 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS Sbjct 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA Sbjct 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLA 780 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ Sbjct 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI Sbjct 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII Sbjct 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI Sbjct 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY Sbjct 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC Sbjct 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC 1187 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC Sbjct 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC 1187 >sp|Q9R117|TYK2_MOUSE Non-receptor tyrosine-protein kinase TYK2 OS=Mus musculus OX=10090 GN=Tyk2 PE=1 SV=3 Length=1184 Score = 1498 bits (3879), Expect = 0.0, Method: Composition-based stats. Identities = 939/1177 (80%), Positives = 1023/1177 (87%), Gaps = 10/1177 (1%) Query 12 SKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCF 71 SK G AQP+ G L VLLHW GP GGEPWVTFS++SLTAEEVCIHIAHKVGITPPC Sbjct 17 SKADGTEAQPLVPTGCLMVLLHWPGPEGGEPWVTFSQTSLTAEEVCIHIAHKVGITPPCL 76 Query 72 NLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTE 131 NLFAL++AQA+VWLPPNHIL+ +D + LYFR+RFYFRNWHGMNP+EPAVYRCG PG E Sbjct 77 NLFALYNAQAKVWLPPNHILDTSQD--MNLYFRMRFYFRNWHGMNPQEPAVYRCGFPGAE 134 Query 132 ASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHL 191 SSD+ QG+QLLD ASFEYLFEQGKHEF+NDV SL +LS+EEEIHHFKNESLGMAFLHL Sbjct 135 TSSDRAEQGVQLLDSASFEYLFEQGKHEFMNDVVSLRDLSSEEEIHHFKNESLGMAFLHL 194 Query 192 CHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLS 251 CHLAL G+PLEE+A++ SFK+CIP SFR+HIRQH+ LTRLRL VFRRFLR F+PG LS Sbjct 195 CHLALSRGVPLEEMAREISFKNCIPHSFRQHIRQHNVLTRLRLHRVFRRFLRAFRPGHLS 254 Query 252 QQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGP 311 QQ+VMVKYLATLERLAPRFG+ER+PVCHL +LAQ E +PCYI++SG DPGPE +GP Sbjct 255 QQVVMVKYLATLERLAPRFGSERIPVCHLEVLAQPERDPCYIQNSGQTAGDPGPELPSGP 314 Query 312 PTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPRE 371 PTHEVLVTGTGGIQW P++ +E G+S NP S GKK KA KA + P+E Sbjct 315 PTHEVLVTGTGGIQWHPLQ----TQESERGNSRGNPHGSRSGKKPKAPKAGEHLTESPQE 370 Query 372 PLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSS 431 P W YFCDF+DI+HVVLKE V IH QDNKCL L L S+A ALSFV+LVDGYFRLTADSS Sbjct 371 PPWTYFCDFQDISHVVLKERRVHIHLQDNKCLLLCLCSQAEALSFVALVDGYFRLTADSS 430 Query 432 HYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRS 491 HYLCHEVAPPRLV SI++GIHGPL++PFVQAKL PEDGLYLI WSTSH +RLILTVA R+ Sbjct 431 HYLCHEVAPPRLVTSIQNGIHGPLMDPFVQAKLWPEDGLYLIQWSTSHLHRLILTVAHRN 490 Query 492 QA-PDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRC 550 A +G + LRLRKFPI QQ GAFVL+GWGRSF S+ +L ALQGC LRAGDDCF L C Sbjct 491 PAFSNGPRGLRLRKFPITQQPGAFVLDGWGRSFASLGDLRLALQGCSLRAGDDCFPLHHC 550 Query 551 CLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRV 610 CLP+P E SNL+IMRG+RA R LNLSQLSFHRV Q EITQLSHLGQGTRTNVYEG LRV Sbjct 551 CLPRPREISNLVIMRGSRAHTRPLNLSQLSFHRVHQDEITQLSHLGQGTRTNVYEGLLRV 610 Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670 G P+EGK+D+ P PG GQ+LRVVLKVLDPSHHDIALAFYETASLMSQVSH HL Sbjct 611 GG---PDEGKVDNGCPPEPGGTSGQQLRVVLKVLDPSHHDIALAFYETASLMSQVSHMHL 667 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730 AF+HGVCVRG ENI+VTE+VEHGPLDVWLRR+RG VPM WKMVVAQQLASALSYLE+KNL Sbjct 668 AFLHGVCVRGSENIIVTEFVEHGPLDVWLRRQRGQVPMTWKMVVAQQLASALSYLEDKNL 727 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANS 790 VHGNVCGRNILLARLGL EGT+PFIKLSDPGVG GALSREERVERIPW APECL GG +S Sbjct 728 VHGNVCGRNILLARLGLEEGTNPFIKLSDPGVGQGALSREERVERIPWTAPECLSGGTSS 787 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLT 850 L TA D WGFGATLLEICFDGEAPLQ R PSEKE FY ++H+LPEPS P+LATLT QCLT Sbjct 788 LGTATDMWGFGATLLEICFDGEAPLQGRGPSEKERFYTKKHQLPEPSSPELATLTRQCLT 847 Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910 YEP QRPSFRTILRDLTRLQP NL VN DSPASDPTVFHKRYLKKIRDLGEGHFGK Sbjct 848 YEPAQRPSFRTILRDLTRLQPQNLVGTSAVNSDSPASDPTVFHKRYLKKIRDLGEGHFGK 907 Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970 VSLYCYDPTNDGTGEMVAVKALK CGPQ RSGW++EI+ILRTLYHEHI+KYKGCCEDQG Sbjct 908 VSLYCYDPTNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVKYKGCCEDQG 967 Query 971 EKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030 EKS+QLVMEYVPLGSLRDYLPRH +GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL Sbjct 968 EKSVQLVMEYVPLGSLRDYLPRHCVGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1027 Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE KFYYASDVWSFGVT Sbjct 1028 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSFGVT 1087 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 LYELLT+CDS+QSP KF ELIG QGQMTVLRLTELLERGERLPRPD+CPCE+YHLMKN Sbjct 1088 LYELLTYCDSNQSPHMKFTELIGHTQGQMTVLRLTELLERGERLPRPDRCPCEIYHLMKN 1147 Query 1151 CWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC 1187 CWETEASFRPTF+NL+PIL+T EKYQGQ PSVFSVC Sbjct 1148 CWETEASFRPTFQNLVPILQTAQEKYQGQVPSVFSVC 1184 >sp|O12990|JAK1_DANRE Tyrosine-protein kinase JAK1 OS=Danio rerio OX=7955 GN=jak1 PE=1 SV=1 Length=1153 Score = 1224 bits (3167), Expect = 0.0, Method: Composition-based stats. Identities = 526/1171 (45%), Positives = 724/1171 (62%), Gaps = 63/1171 (5%) Query 23 AAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQ 82 AM GL++ + A + F ++ TAE++C+ A + I+P C NLFAL++ Sbjct 29 TAMKGLEIHFYLADTHQ----LEFFKACYTAEDLCVEAAKRCRISPLCHNLFALYEESQD 84 Query 83 VWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRC--GPPGTEASSDQTAQG 140 +W PNH+ ++ + S+ L++R+RFYF NWHG + E V+R + +S +T +G Sbjct 85 LWYAPNHVFKVTDETSIKLHYRMRFYFTNWHGTSEIESPVWRHTLSKQKSVLNSQKTTEG 144 Query 141 MQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGI 200 LLD AS +YLF QG+++F+ ++ + T+EE H +NE LGMA L + H A + + Sbjct 145 TPLLDAASLDYLFAQGQYDFLRGLSPVRPTQTDEEHHEIENECLGMAVLAITHHAKSNNL 204 Query 201 PLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQ-----QMV 255 PL +TS+K IP S R I+Q + LTR+R+ NVF+ FL +F + + Sbjct 205 PLSGAGAETSYKRFIPDSLNRTIKQRNFLTRIRISNVFKNFLNEFNSKTIQDSNIGLYDL 264 Query 256 MVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHE 315 VKYL+TLE L G E +L++ ++EG P A P ++ G +E Sbjct 265 KVKYLSTLETLTQGVGREIFKPKNLKVTGESEGSP--------AQMLPLGDNGMG---YE 313 Query 316 VLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVG--QPADRPREPL 373 V V GT GI W P + K K+ K G Q D+ ++ Sbjct 314 VQVYGTTGISW---------------RRKPAPNQLILKDKPKSKKIKGDKQWNDKKKDSG 358 Query 374 WAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHY 433 W F DF +ITH+V+K+ CV+I+RQDNK +EL L R AALSF +LVDGYFRLT D+ HY Sbjct 359 WTLFSDFHEITHIVIKDCCVTIYRQDNKTMELDLFYRDAALSFAALVDGYFRLTVDAHHY 418 Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILTV-AQ 489 LC +VAP +V ++ +G HGP+ + KLR E +G Y++ WS + +I+TV Sbjct 419 LCTDVAPSSVVQNLENGCHGPICTEYAIHKLRQEGNEEGTYVLRWSCTEYNFIIMTVVCI 478 Query 490 RSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRR 549 + + + F IE + L G P+++EL LQG LLR + F LRR Sbjct 479 ELDLCESRPVPQYKNFQIETSPQGYRLYGTDTFRPTLKELLEHLQGQLLRTDNLRFQLRR 538 Query 550 CCLPQPGETSNLIIMRGARAS--PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 CC PQP E SNL++M R + +SQLSF R+ ++EI Q HLG+GTRTN+Y G Sbjct 539 CCPPQPREISNLLVMTTDREPVPQKKTQVSQLSFDRILKEEIVQGEHLGRGTRTNIYAGI 598 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667 L+ + + + G QE++VVLKVL H DI+LAF+ETAS+M Q+SH Sbjct 599 LKPKSDDEDDLG------------GYSQEVKVVLKVLGSGHRDISLAFFETASMMRQISH 646 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 H A ++GVCVR ENIMV E+V++GPLD+++RR+ + AWK VA+QLASALSYLE+ Sbjct 647 KHTALLYGVCVRHQENIMVEEFVQYGPLDLFMRRQTTPLSTAWKFQVAKQLASALSYLED 706 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGG 787 K +VHG VC +NIL+AR GL PFIKLSDPG+ + LSREE V+RIPW+APEC+ Sbjct 707 KKMVHGYVCSKNILVARDGLDGEGGPFIKLSDPGIPITVLSREECVDRIPWIAPECVKDT 766 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ 847 AN L+ A DKW FG TL EIC++GE PL+ + SEKE FY Q +L P C +LA L + Sbjct 767 AN-LTIAADKWSFGTTLWEICYNGEIPLKDKKLSEKERFYAAQCQLATPDCDELAKLMTH 825 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 C+TY+P QR FR I+ + + DPTVF KR+LKKIRDLGEGH Sbjct 826 CMTYDPRQRLFFRAIV---RDIVMVEKQNPSIQPVPMLEVDPTVFEKRFLKKIRDLGEGH 882 Query 908 FGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 FGKV L YDP D TGE+VAVK+LK + + + +EI ILR LYHE+I+KYKG C Sbjct 883 FGKVELCRYDPRGDRTGELVAVKSLKPENREEQSNNLWREIHILRELYHENIVKYKGICN 942 Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 ++G +S++L+ME++P GSL++YLPR+ I L L ++ QIC+GM YL +++YIHRDLA Sbjct 943 EEGGRSIKLIMEFLPAGSLKEYLPRNKAHINLKTLHNYSVQICQGMDYLGSRNYIHRDLA 1002 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 ARNVL++N+ VKIGDFGL K++ + YY V++D DSPVFWYAPECL KFY ASDVW Sbjct 1003 ARNVLVENEGTVKIGDFGLTKSIKDNEGYYTVKDDLDSPVFWYAPECLIHCKFYRASDVW 1062 Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 SFGVT+YELLT+CD+S SP + FL+LIG GQMTV RL ++LE G+RLPRPD C ++Y Sbjct 1063 SFGVTMYELLTYCDASCSPMSVFLKLIGPTHGQMTVTRLVKVLEEGKRLPRPDDCSEQLY 1122 Query 1146 HLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 +LM+ CWE R F++LI + + + Sbjct 1123 NLMRRCWEATPEKRIDFKSLIANFQQMLDNL 1153 Score = 122 bits (305), Expect = 1e-26, Method: Composition-based stats. Identities = 76/416 (18%), Positives = 144/416 (35%), Gaps = 59/416 (14%) Query 798 WGFGA---TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP--EPSCPQLATLTS----QC 848 + F +E+ P+ + E + +RL + P L L Q Sbjct 468 YNFIIMTVVCIELDLCESRPVPQYKNFQIET-SPQGYRLYGTDTFRPTLKELLEHLQGQL 526 Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 L + + R + + + + + K + H Sbjct 527 LRTDNLRFQLRRCCPPQPREISNLLVMTTDREPVPQKKTQVSQLSFDRILKEEIVQGEHL 586 Query 909 GK-----VSLYCYDPTNDGTGE--------MVAVKALKADCGPQHRSGWKQEIDILRTLY 955 G+ + P +D + V +K L + + ++ ++R + Sbjct 587 GRGTRTNIYAGILKPKSDDEDDLGGYSQEVKVVLKVLGSGHRDISLAFFET-ASMMRQIS 645 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLF--AQQICEGMAY 1013 H+H G C E +V E+V G L ++ R + L+ F A+Q+ ++Y Sbjct 646 HKHTALLYGVCVRHQEN--IMVEEFVQYGPLDLFMRRQTTPLSTAWKFQVAKQLASALSY 703 Query 1014 LHAQHYIHRDLAARNVLLDNDRL-------VKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 L + +H + ++N+L+ D L +K+ D G+ RE+ + Sbjct 704 LEDKKMVHGYVCSKNILVARDGLDGEGGPFIKLSDPGI-------PITVLSREECVDRIP 756 Query 1067 WYAPECLKEY-KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 W APEC+K+ A+D WSFG TL+E+ C + + P + Sbjct 757 WIAPECVKDTANLTIAADKWSFGTTLWEI---CYNGEIPLKD-----------KKLSEKE 802 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 +L PD E+ LM +C + R F ++ + V ++ P Sbjct 803 RFYAAQCQLATPDC--DELAKLMTHCMTYDPRQRLFFRAIVRDIVMVEKQNPSIQP 856 >sp|P23458|JAK1_HUMAN Tyrosine-protein kinase JAK1 OS=Homo sapiens OX=9606 GN=JAK1 PE=1 SV=2 Length=1154 Score = 1219 bits (3155), Expect = 0.0, Method: Composition-based stats. Identities = 529/1180 (45%), Positives = 730/1180 (62%), Gaps = 60/1180 (5%) Query 10 RGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPP 69 R SK A G++V+ + + + TAEE+CI A I+P Sbjct 20 RSSKK--TEVNLEAPEPGVEVIFYLSDREP----LRLGSGEYTAEELCIRAAQACRISPL 73 Query 70 CFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPG 129 C NLFAL+D ++W PN + + SL L++R+RFYF NWHG N E +V+R P Sbjct 74 CHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTNDNEQSVWRHSPKK 133 Query 130 TEASSDQT--AQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMA 187 + ++ LLD +S EYLF QG+++ V +A + + TE++ H +NE LGMA Sbjct 134 QKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQDGHDIENECLGMA 193 Query 188 FLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQP 247 L + H A+ + L E+ K S+K IP + + IRQ + LTR+R+ NVF+ FL++F Sbjct 194 VLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFNN 253 Query 248 GRLSQ-----QMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTD 302 + + VKYLATLE L +G E L + ++ E + D G Sbjct 254 KTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMNWFHSNDGGNVL-- 311 Query 303 PGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAV 362 +EV+VTG GIQW + + + S + K HK Sbjct 312 ----------YYEVMVTGNLGIQW--------RHKPNVVSVEKEKNKLKRKKLENKHKK- 352 Query 363 GQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDG 422 + ++ RE W F F +ITH+V+KE VSI++QDNK +EL L S ALSFVSLVDG Sbjct 353 DEEKNKIREE-WNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDG 411 Query 423 YFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSH 479 YFRLTAD+ HYLC +VAPP +V +I++G HGP+ + KLR E +G+Y++ WS + Sbjct 412 YFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTD 471 Query 480 PYRLILTVA--QRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCL 537 +++TV ++S+ G Q + + F IE Q G + L G RSFPS+ +L + L+ + Sbjct 472 FDNILMTVTCFEKSEQVQGAQK-QFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQI 530 Query 538 LRAGDDCFSLRRCCLPQPGETSNLII-MRGARASPRTLNLSQLSFHRVDQKEITQLSHLG 596 LR + F L+RCC P+P E SNL++ + A+ +SQLSF R+ +K++ Q HLG Sbjct 531 LRTDNISFMLKRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLG 590 Query 597 QGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFY 656 +GTRT++Y G L + G ++++V+LKVLDPSH DI+LAF+ Sbjct 591 RGTRTHIYSGTLMDYKDDE--------------GTSEEKKIKVILKVLDPSHRDISLAFF 636 Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 E AS+M QVSH H+ +++GVCVR ENIMV E+VE GPLD+++ R+ + WK VA+ Sbjct 637 EAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAK 696 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI 776 QLASALSYLE+K+LVHGNVC +N+LLAR G+ PFIKLSDPG+ + LSR+E +ERI Sbjct 697 QLASALSYLEDKDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGIPITVLSRQECIERI 756 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836 PW+APEC+ N LS A DKW FG TL EIC++GE PL+ ++ EKE FY+ + R P Sbjct 757 PWIAPECVEDSKN-LSVAADKWSFGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTP 815 Query 837 SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896 SC +LA L ++C+ Y+P QRP FR I+RD+ +L+ N V P + F KR+ Sbjct 816 SCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQNPDIVSEKKPATEVDPTH-FEKRF 874 Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 LK+IRDLGEGHFGKV L YDP D TGE VAVK+LK + G H + K+EI+ILR LYH Sbjct 875 LKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYH 934 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYL 1014 E+I+KYKG C + G ++L+ME++P GSL++YLP++ I L Q L +A QIC+GM YL Sbjct 935 ENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYL 994 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 ++ Y+HRDLAARNVL++++ VKIGDFGL KA+ EYY V++D DSPVFWYAPECL Sbjct 995 GSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLM 1054 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + KFY ASDVWSFGVTL+ELLT+CDS SP FL++IG GQMTV RL L+ G+RL Sbjct 1055 QSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRL 1114 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 P P CP EVY LM+ CWE + S R +F+NLI + + + Sbjct 1115 PCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK 1154 Score = 150 bits (380), Expect = 2e-35, Method: Composition-based stats. Identities = 77/358 (22%), Positives = 137/358 (38%), Gaps = 55/358 (15%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 + +C +P + + L A K+ L + L Sbjct 539 MLKRCCQPKPREISNL---------LVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHL 589 Query 904 GEG---HFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS---GWKQEIDILRTLYHE 957 G G H +L Y ++GT E +K + P HR + + ++R + H+ Sbjct 590 GRGTRTHIYSGTLMDYKD-DEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHK 648 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015 HI+ G C E +V E+V G L ++ R S + A+Q+ ++YL Sbjct 649 HIVYLYGVCVRDVEN--IMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLE 706 Query 1016 AQHYIHRDLAARNVLLDNDRL-------VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 + +H ++ +N+LL + + +K+ D G+ R++ + W Sbjct 707 DKDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGI-------PITVLSRQECIERIPWI 759 Query 1069 APECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APEC+++ K A+D WSFG TL+E+ C + + P T++ Sbjct 760 APECVEDSKNLSVAADKWSFGTTLWEI---CYNGEIPLKD-----------KTLIEKERF 805 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 E R P E+ LM C + + RP F ++ + + E Q P + S Sbjct 806 YESRCRPVTPSC--KELADLMTRCMNYDPNQRPFFRAIMRDINKLEE----QNPDIVS 857 >sp|P52332|JAK1_MOUSE Tyrosine-protein kinase JAK1 OS=Mus musculus OX=10090 GN=Jak1 PE=1 SV=1 Length=1153 Score = 1219 bits (3153), Expect = 0.0, Method: Composition-based stats. Identities = 526/1173 (45%), Positives = 731/1173 (62%), Gaps = 59/1173 (5%) Query 17 DGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFAL 76 + + G++V + + TAEE+CI A + I+P C NLFAL Sbjct 25 TEVKQVVPEPGVEVTFYLLDREP----LRLGSGEYTAEELCIRAAQECSISPLCHNLFAL 80 Query 77 FDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQ 136 +D ++W PN I+ + SL L++R+RFYF NWHG N E +V+R P + ++ Sbjct 81 YDESTKLWYAPNRIITVDDKTSLRLHYRMRFYFTNWHGTNDNEQSVWRHSPKKQKNGYEK 140 Query 137 T--AQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHL 194 + LLD +S EYLF QG+++ + +A + + TE++ H +NE LGMA L + H Sbjct 141 KRVPEATPLLDASSLEYLFAQGQYDLIKCLAPIRDPKTEQDGHDIENECLGMAVLAISHY 200 Query 195 ALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQ-- 252 A+ + L E+ K S+K IP + + IRQ + LTR+R+ NVF+ FL++F + Sbjct 201 AMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRINNVFKDFLKEFNNKTICDSS 260 Query 253 -QMVMVKYLATLER--LAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAA 309 + VKYLATLE L +G E L + ++ E C+ DSG Sbjct 261 VHDLKVKYLATLETSTLTKHYGAEIFETSMLLISSENELSRCHSNDSGNV---------- 310 Query 310 GPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRP 369 +EV+VTG GIQW ++ N + + + K K ++ Sbjct 311 ---LYEVMVTGNLGIQW---RQKPNVVPVEKEKNKLKRKKLEYNKHKK-----DDERNKL 359 Query 370 REPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTAD 429 RE W F F +ITH+V+KE VSI++QDNK +EL L SR ALSFVSLVDGYFRLTAD Sbjct 360 REE-WNNFSYFPEITHIVIKESVVSINKQDNKNMELKLSSREEALSFVSLVDGYFRLTAD 418 Query 430 SSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILT 486 + HYLC +VAPP +V +I++G HGP+ + KLR E +G+Y++ WS + +++T Sbjct 419 AHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMT 478 Query 487 VA--QRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDC 544 V ++S+ G + + + F IE Q G + L G FPS+R+L L+ +LR + Sbjct 479 VTCFEKSEVLGGQK--QFKNFQIEVQKGRYSLHGSMDHFPSLRDLMNHLKKQILRTDNIS 536 Query 545 FSLRRCCLPQPGETSNLII-MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603 F L+RCC P+P E SNL++ + A+ ++SQLSF R+ +K+I Q HLG+GTRT++ Sbjct 537 FVLKRCCQPKPREISNLLVATKKAQEWQPVYSMSQLSFDRILKKDIIQGEHLGRGTRTHI 596 Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663 Y G L + G ++++V+LKVLDPSH DI+LAF+E AS+M Sbjct 597 YSGTLLDYKDEE--------------GIAEEKKIKVILKVLDPSHRDISLAFFEAASMMR 642 Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723 QVSH H+ +++GVCVR ENIMV E+VE GPLD+++ R+ + WK VA+QLASALS Sbjct 643 QVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDALTTPWKFKVAKQLASALS 702 Query 724 YLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPEC 783 YLE+K+LVHGNVC +N+LLAR G+ PFIKLSDPG+ + L+R+E +ERIPW+APEC Sbjct 703 YLEDKDLVHGNVCTKNLLLAREGIDSDIGPFIKLSDPGIPVSVLTRQECIERIPWIAPEC 762 Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT 843 + N LS A DKW FG TL EIC++GE PL+ ++ EKE FY+ + R PSC +LA Sbjct 763 VEDSKN-LSVAADKWSFGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELAD 821 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 L ++C+ Y+P QRP FR I+RD+ +L+ N V P + F KR+LK+IRDL Sbjct 822 LMTRCMNYDPNQRPFFRAIMRDINKLEEQNPDIVSEKQPTTEVDPTH-FEKRFLKRIRDL 880 Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963 GEGHFGKV L YDP D TGE VAVK+LK + G H + K+EI+ILR LYHE+I+KYK Sbjct 881 GEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYK 940 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G C + G ++L+ME++P GSL++YLP++ I L Q L +A QIC+GM YL ++ Y+H Sbjct 941 GICMEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAIQICKGMDYLGSRQYVH 1000 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RDLAARNVL++++ VKIGDFGL KA+ EYY V++D DSPVFWYAPECL + KFY A Sbjct 1001 RDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIA 1060 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 SDVWSFGVTL+ELLT+CDS SP FL++IG GQMTV RL + L+ G+RLP P CP Sbjct 1061 SDVWSFGVTLHELLTYCDSDFSPMALFLKMIGPTHGQMTVTRLVKTLKEGKRLPCPPNCP 1120 Query 1142 CEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 EVY LM+ CWE + S R TF+NLI + + + Sbjct 1121 DEVYQLMRKCWEFQPSNRTTFQNLIEGFEALLK 1153 Score = 148 bits (373), Expect = 1e-34, Method: Composition-based stats. Identities = 73/357 (20%), Positives = 132/357 (37%), Gaps = 53/357 (15%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 + +C +P + + L A K+ + + L Sbjct 538 VLKRCCQPKPREISNL---------LVATKKAQEWQPVYSMSQLSFDRILKKDIIQGEHL 588 Query 904 GEGHFGKVSLYCYDPTNDGTG--EMVAVKALKADCGPQHRS---GWKQEIDILRTLYHEH 958 G G + D G E +K + P HR + + ++R + H+H Sbjct 589 GRGTRTHIYSGTLLDYKDEEGIAEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKH 648 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHA 1016 I+ G C E +V E+V G L ++ R S + A+Q+ ++YL Sbjct 649 IVYLYGVCVRDVEN--IMVEEFVEGGPLDLFMHRKSDALTTPWKFKVAKQLASALSYLED 706 Query 1017 QHYIHRDLAARNVLLDNDRL-------VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + +H ++ +N+LL + + +K+ D G+ R++ + W A Sbjct 707 KDLVHGNVCTKNLLLAREGIDSDIGPFIKLSDPGI-------PVSVLTRQECIERIPWIA 759 Query 1070 PECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PEC+++ K A+D WSFG TL+E+ C + + P T++ Sbjct 760 PECVEDSKNLSVAADKWSFGTTLWEI---CYNGEIPLKD-----------KTLIEKERFY 805 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 E R P E+ LM C + + RP F ++ + + E Q P + S Sbjct 806 ESRCRPVTPSC--KELADLMTRCMNYDPNQRPFFRAIMRDINKLEE----QNPDIVS 856 >sp|Q75R65|JAK2_CHICK Tyrosine-protein kinase JAK2 OS=Gallus gallus OX=9031 GN=JAK2 PE=2 SV=1 Length=1129 Score = 1172 bits (3031), Expect = 0.0, Method: Composition-based stats. Identities = 441/1200 (37%), Positives = 637/1200 (53%), Gaps = 130/1200 (11%) Query 15 VGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLF 74 +G+ + P L+V L+++ G ++ F AEE+CI GI P N+F Sbjct 24 LGNTSAPKQTEPLLQVYLYYSPGKTGGDYLQFPAGEYVAEEICIVACKACGIMPVYHNMF 83 Query 75 ALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASS 134 AL +VW PPNHI + L L +RIRFYF +W+ Y G+E+ Sbjct 84 ALMSETERVWYPPNHIFHVDEATRLKLLYRIRFYFPHWYCNGTSRACRYGI-IRGSES-- 140 Query 135 DQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHL 194 +LD YLF Q + +F++ + H + E LGMA L + + Sbjct 141 -------PVLDDLVMSYLFAQWRKDFLDGWIQM------PVTHETQEECLGMAVLDMMRV 187 Query 195 ALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQM 254 A V S+K +P+ R I+++ LTR R+R FR+F++ F + + + Sbjct 188 AKEKDQTPLAVYNSVSYKMFLPKCVRAKIQEYHILTRKRIRYRFRKFIQQFGQCKATARN 247 Query 255 VMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTH 314 + +KYL LE L F +E V +PG + + Sbjct 248 LKLKYLINLETLQSAFYSEVFEVK-----------------------EPGGDPSGEESFA 284 Query 315 EVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLW 374 +++TG GGIQ S G+ ++ Sbjct 285 TIVITGNGGIQC---------------SRGKLKNCETLAEQD-----------------L 312 Query 375 AYFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFR 425 +CDF DI V +K+ V+IH+QD+K LE S ALSFVSL+DGY+R Sbjct 313 QTYCDFPDIIDVSIKQASQEGSSERRIVTIHKQDSKNLEAEFQSLREALSFVSLIDGYYR 372 Query 426 LTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYR 482 LTAD+ HYLC EVAPP ++ +I+ HGP+ F KL+ + G Y++ S + Sbjct 373 LTADAHHYLCKEVAPPSVLENIQSNCHGPIFMDFAINKLKKAGNQTGFYVLRCSPKDFKK 432 Query 483 LILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGD 542 LT A + + + K ++G + L G RSF ++++L Q +R+ Sbjct 433 YFLTFAIERENATDYKHCLITK----NENGEYNLSGTKRSFGNLKDLLTCYQTETVRSDS 488 Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTL-------NLSQLSFHRVDQKEITQLSHL 595 F +CC P+P + SNL++ R S N+SQ+ FH++ +++ L Sbjct 489 IIFQFIKCCPPKPKDKSNLLVFRSNSVSDVPSSPTLQRHNVSQMVFHKIRNEDLIFEESL 548 Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655 GQGT T +++G + G + V+LKVLD H + + +F Sbjct 549 GQGTFTKIFKGIRKEVGDYGQLH-----------------QTEVLLKVLDKVHRNYSESF 591 Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715 +E AS+MSQ+S+ HL +GVCV G ENI+V EYV+ G LD +L++ + + + WK+ VA Sbjct 592 FEAASMMSQLSYKHLVLNYGVCVCGEENILVQEYVKFGSLDTYLKKNKNVINILWKLEVA 651 Query 716 QQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 +QLA A+ +LE+K LVHGNVC +NILL G PFIKLSDPG+ + L R+ +E Sbjct 652 KQLALAMHFLEDKGLVHGNVCAKNILLIREEDRKSGNLPFIKLSDPGISITVLPRDILLE 711 Query 775 RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834 RIPW+ PEC+ LS A DKW FG TL EIC G+ PL + S K FY+ +H+LP Sbjct 712 RIPWVPPECI-ENPRQLSLATDKWSFGTTLWEICSGGDKPLSALDSSRKLQFYEDRHQLP 770 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP--------- 885 P+ +LA L + C+ YEP RPSFR I+RDL L + + + Sbjct 771 APNWTELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNIRTGALGFS 830 Query 886 ----ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L +H Sbjct 831 GAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTEEHL 889 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQ 999 +++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H + + Sbjct 890 RDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERLDHKK 949 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 LLL+A QIC+GM YL + Y+HRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V+E Sbjct 950 LLLYASQICKGMEYLGTKRYVHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKE 1009 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQGQ 1118 G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG QGQ Sbjct 1010 PGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQ 1069 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 M V L ELL+ RLPRPD CP E+Y +MK CW + RPTF +L + + + G Sbjct 1070 MIVFHLIELLKNNGRLPRPDGCPDEIYAIMKECWNNNVAQRPTFRDLAQRVDQIRDNMGG 1129 >sp|Q09178|JAK1_CYPCA Tyrosine-protein kinase JAK1 OS=Cyprinus carpio OX=7962 GN=jak1 PE=2 SV=1 Length=1156 Score = 1164 bits (3011), Expect = 0.0, Method: Composition-based stats. Identities = 511/1171 (44%), Positives = 697/1171 (60%), Gaps = 58/1171 (5%) Query 22 MAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCF-NLFALFDAQ 80 + M GL++ + + + + TAE++C+ + + C NLFAL + Sbjct 28 LTVMKGLEIHFYLPDTHQ----LEYFKDCHTAEDLCVEGCQEDATSHLCADNLFALSEES 83 Query 81 AQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCG--PPGTEASSDQTA 138 +W PNH +I + S+ L++R+RFYF NWH E V+R + S + Sbjct 84 QDLWYAPNHAFKITEETSIKLHYRMRFYFTNWHAPVRTESPVWRHSLFKHKGVSVSPKGP 143 Query 139 QGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRH 198 +G LLD AS EYLF QG+++F+ +A + E E H +NE LGMA L + H A + Sbjct 144 EGTPLLDAASLEYLFAQGQYDFLRGLAPVRAPQNEAEKHEIENECLGMAVLAITHHAKSN 203 Query 199 GIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQ-----PGRLSQQ 253 +PL V +TS+K IP S R I+Q + NVF+ FL +F ++ Sbjct 204 DLPLSGVGAETSYKRFIPDSLNRTIKQRNFSHVYVYNNVFKNFLNEFNSKTIQDSNITLY 263 Query 254 MVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPT 313 + VKYL+TLE L G E + L++ +++G P A T P + G Sbjct 264 DLKVKYLSTLETLTQGLGRETIEPKILKVSGESDGSP--------ALTLPSGDDGLG--- 312 Query 314 HEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPL 373 +EV V+GT GI W S +N KA K + + R+ + Sbjct 313 YEVQVSGTTGISWRRKPVPNILIVKDKTKSKKN----------KADKQSKKEMTK-RKTV 361 Query 374 WAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHY 433 F DF +ITH+V+KE C +I+ QDNK +EL L R AALSF +LVDGYFRLT D+ HY Sbjct 362 MTIFSDFFEITHIVIKESCATIYSQDNKTMELDLFYRDAALSFAALVDGYFRLTVDAHHY 421 Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILTV-AQ 489 LC EVAP +V ++ +G HGP+ + KLR E +G Y++ WS + +I+TV Sbjct 422 LCTEVAPSSVVQNLENGCHGPICTEYAIHKLRQEGNEEGTYVLRWSCTDYNYIIMTVVCI 481 Query 490 RSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRR 549 + + + F IE + L G P+++EL LQG LR + F Sbjct 482 EMDLCESRPVPQYKNFQIETSPQGYRLYGTDTFRPTLKELLEHLQGQNLRTENLRFQPVL 541 Query 550 CCLPQPGETSNLIIMRGARA--SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 L QP + SNL++M R S R +SQLSFHR+ ++EI Q HLG+GTRTN+Y G Sbjct 542 VGLGQPRKISNLLVMTRDREPDSQRQPQVSQLSFHRILKEEIVQGEHLGRGTRTNIYSGV 601 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667 L+++ D + G QE++V+LKVL H DI+LAF+ETAS+M Q+SH Sbjct 602 LKLKSEDDDDMG------------GYSQEVKVILKVLGSGHRDISLAFFETASMMRQISH 649 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 H+A ++GVCVR ENIMV E+V++GPLD+++RR+ + AWK VA+QLA ALSYLE+ Sbjct 650 KHIALLYGVCVRHQENIMVEEFVQYGPLDLFMRRQSIPLSTAWKFQVAKQLAGALSYLED 709 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGG 787 K LVHGNVC +NIL+AR GL PFIKLSDPG+ + LSREE V+R+PW+APEC+ Sbjct 710 KKLVHGNVCSKNILVARDGLDGEGGPFIKLSDPGIPITVLSREECVDRLPWIAPECVQDT 769 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ 847 AN LS A DKWGFG TL EIC++GE PL+ + +EKE FY Q +L P C +LA L + Sbjct 770 AN-LSIAADKWGFGTTLWEICYNGEIPLKDKKLTEKERFYAAQCQLASPDCEELAKLMTH 828 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 C+TY+P QR FR I+ + + DPTVF KR+LKKIRDLGEGH Sbjct 829 CMTYDPRQRLFFRAIV---RDIDMVEKQNPSIQPVPMLEVDPTVFEKRFLKKIRDLGEGH 885 Query 908 FGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 FGKV L YDP D TGE+VAVK+LK + + S +EI ILR LYHE+I+KYKG Sbjct 886 FGKVELCRYDPRGDRTGELVAVKSLKPENREEQSSNLWREIHILRELYHENIVKYKGIWH 945 Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 ++G +S++L+ME++P GSL++YLPR+ I L LL +A QIC+GM L +++YIHRDLA Sbjct 946 EEGGRSIKLIMEFLPAGSLKEYLPRNKAHIDLKTLLNYAVQICQGMDLLASRNYIHRDLA 1005 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 ARNVL++N+ VKIGDFGL K++ + YY V++D DSPVFWYAPECL KFY ASDVW Sbjct 1006 ARNVLVENENTVKIGDFGLTKSIKDNEGYYTVKDDLDSPVFWYAPECLIHCKFYRASDVW 1065 Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 SFGVT+YELLT+CD S SP + FL +IG GQMTV RL ++LE G+RLP+PD C +Y Sbjct 1066 SFGVTMYELLTYCDISCSPMSVFLTMIGPTHGQMTVTRLVKVLEEGKRLPKPDGCSDRLY 1125 Query 1146 HLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 LM+ CWE R F+ LI + + + Sbjct 1126 CLMRRCWEATPEKRIDFKGLIANFQQMIDNQ 1156 Score = 126 bits (316), Expect = 6e-28, Method: Composition-based stats. Identities = 63/266 (24%), Positives = 111/266 (42%), Gaps = 38/266 (14%) Query 929 VKALKADCGPQHRS---GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 VK + G HR + + ++R + H+HI G C E +V E+V G Sbjct 619 VKVILKVLGSGHRDISLAFFETASMMRQISHKHIALLYGVCVRHQEN--IMVEEFVQYGP 676 Query 986 LRDYLPRHSIGLAQLLLF--AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL------- 1036 L ++ R SI L+ F A+Q+ ++YL + +H ++ ++N+L+ D L Sbjct 677 LDLFMRRQSIPLSTAWKFQVAKQLAGALSYLEDKKLVHGNVCSKNILVARDGLDGEGGPF 736 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFYYASDVWSFGVTLYELL 1095 +K+ D G+ RE+ + W APEC+++ A+D W FG TL+E+ Sbjct 737 IKLSDPGI-------PITVLSREECVDRLPWIAPECVQDTANLSIAADKWGFGTTLWEI- 788 Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155 C + + P K +L + +L C E+ LM +C + Sbjct 789 --CYNGEIP-LKDKKLTEKERFYAAQCQLAS-----------PDC-EELAKLMTHCMTYD 833 Query 1156 ASFRPTFENLIPILKTVHEKYQGQAP 1181 R F ++ + V ++ P Sbjct 834 PRQRLFFRAIVRDIDMVEKQNPSIQP 859 >sp|Q5RB23|JAK2_PONAB Tyrosine-protein kinase JAK2 OS=Pongo abelii OX=9601 GN=JAK2 PE=2 SV=1 Length=1132 Score = 1147 bits (2968), Expect = 0.0, Method: Composition-based stats. Identities = 435/1202 (36%), Positives = 636/1202 (53%), Gaps = 132/1202 (11%) Query 15 VGDGAQPMAAMGGLKVLLHWAGPGGGE-PWVTFSESSLTAEEVCIHIAHKVGITPPCFNL 73 + A M + + ++ + G E ++TF AEE+CI + GITP N+ Sbjct 25 ISGNANSMKQIDPVLLVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNM 84 Query 74 FALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEAS 133 FAL ++W PPNH+ I + +RIRFYF W+ YR G Sbjct 85 FALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPRWYCSGSNRA--YRHGISRG--- 139 Query 134 SDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCH 193 LLD YLF Q +H+FV+ + H + E LGMA L + Sbjct 140 -----AEAPLLDDFVMSYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLDMMR 188 Query 194 LALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQ 253 +A + + S+K +P+ R I+ + LTR R+R FRRF++ F + + + Sbjct 189 IAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATAR 248 Query 254 MVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPT 313 + +KYL LE L F TE+ V +PG + Sbjct 249 NLKLKYLINLETLQSAFYTEKFEVK-----------------------EPGSGPSGEEIF 285 Query 314 HEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPL 373 +++TG GGIQW S G++ ++ ++ Sbjct 286 ATIIITGNGGIQW---------------SRGKHKESETLTEQD----------------- 313 Query 374 WAYFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYF 424 +CDF +I V +K+ V+IH+QD K LE+ L S ALSFVSL+DGY+ Sbjct 314 LQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYY 373 Query 425 RLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPY 481 RLTAD+ HYLC EVAPP ++ +I+ HGP+ F +KL+ + GLY++ S Sbjct 374 RLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFN 433 Query 482 RLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAG 541 + LT A + + + K ++ + L G ++F S+++L Q +R+ Sbjct 434 KYFLTFAVERENVIEYKHCLITK----NENEEYNLSGTKKNFSSLKDLLNCYQMETVRSD 489 Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEITQLS 593 + F +CC P+P + SNL++ R S R +++Q+ FH++ +++ Sbjct 490 NIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNE 549 Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LGQGT T +++G R G E V+LKVLD +H + + Sbjct 550 SLGQGTFTKIFKGVRREVGDYGQLH-----------------ETEVLLKVLDKAHRNYSE 592 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 +F+E AS+MS++SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+ Sbjct 593 SFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLE 652 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREER 772 VA+QLA A+ +LE L+HGNVC +NILL G PFIKLSDPG+ + L ++ Sbjct 653 VAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDIL 712 Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832 ERIPW+ PEC+ +L+ A DKW FG TL EIC G+ PL + K FY+ +H+ Sbjct 713 QERIPWVPPECI-ENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQ 771 Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA------ 886 LP P +LA L + C+ YEP RPSFR I+RDL L + + + Sbjct 772 LPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALG 831 Query 887 -------SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L + Sbjct 832 FSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTEE 890 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGL 997 H +++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I Sbjct 891 HLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDH 950 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 +LL + QIC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V Sbjct 951 KKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKV 1010 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQ 1116 +E G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG Q Sbjct 1011 KEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQ 1070 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 GQM V L ELL+ RLPRPD CP E+Y +M CW + RP+F +L + + + Sbjct 1071 GQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM 1130 Query 1177 QG 1178 G Sbjct 1131 AG 1132 >sp|O60674|JAK2_HUMAN Tyrosine-protein kinase JAK2 OS=Homo sapiens OX=9606 GN=JAK2 PE=1 SV=2 Length=1132 Score = 1145 bits (2963), Expect = 0.0, Method: Composition-based stats. Identities = 435/1202 (36%), Positives = 635/1202 (53%), Gaps = 132/1202 (11%) Query 15 VGDGAQPMAAMGGLKVLLHWAGPGGGE-PWVTFSESSLTAEEVCIHIAHKVGITPPCFNL 73 + A M + + + + G E ++TF AEE+CI + GITP N+ Sbjct 25 ISGNANSMKQIDPVLQVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNM 84 Query 74 FALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEAS 133 FAL ++W PPNH+ I + +RIRFYF W+ YR G Sbjct 85 FALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPRWYCSGSNRA--YRHGISRG--- 139 Query 134 SDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCH 193 LLD YLF Q +H+FV+ + H + E LGMA L + Sbjct 140 -----AEAPLLDDFVMSYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLDMMR 188 Query 194 LALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQ 253 +A + + S+K +P+ R I+ + LTR R+R FRRF++ F + + + Sbjct 189 IAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATAR 248 Query 254 MVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPT 313 + +KYL LE L F TE+ V +PG + Sbjct 249 NLKLKYLINLETLQSAFYTEKFEVK-----------------------EPGSGPSGEEIF 285 Query 314 HEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPL 373 +++TG GGIQW S G++ ++ ++ Sbjct 286 ATIIITGNGGIQW---------------SRGKHKESETLTEQD----------------- 313 Query 374 WAYFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYF 424 +CDF +I V +K+ V+IH+QD K LE+ L S ALSFVSL+DGY+ Sbjct 314 LQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYY 373 Query 425 RLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPY 481 RLTAD+ HYLC EVAPP ++ +I+ HGP+ F +KL+ + GLY++ S Sbjct 374 RLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFN 433 Query 482 RLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAG 541 + LT A + + + K ++ + L G ++F S+++L Q +R+ Sbjct 434 KYFLTFAVERENVIEYKHCLITK----NENEEYNLSGTKKNFSSLKDLLNCYQMETVRSD 489 Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEITQLS 593 + F +CC P+P + SNL++ R S R +++Q+ FH++ +++ Sbjct 490 NIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNE 549 Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LGQGT T +++G R G E V+LKVLD +H + + Sbjct 550 SLGQGTFTKIFKGVRREVGDYGQLH-----------------ETEVLLKVLDKAHRNYSE 592 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 +F+E AS+MS++SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+ Sbjct 593 SFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLE 652 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREER 772 VA+QLA A+ +LE L+HGNVC +NILL G PFIKLSDPG+ + L ++ Sbjct 653 VAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDIL 712 Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832 ERIPW+ PEC+ +L+ A DKW FG TL EIC G+ PL + K FY+ +H+ Sbjct 713 QERIPWVPPECI-ENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQ 771 Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA------ 886 LP P +LA L + C+ YEP RPSFR I+RDL L + + + Sbjct 772 LPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALG 831 Query 887 -------SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L + Sbjct 832 FSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTEE 890 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGL 997 H +++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I Sbjct 891 HLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDH 950 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 +LL + QIC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V Sbjct 951 IKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKV 1010 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQ 1116 +E G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG Q Sbjct 1011 KEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQ 1070 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 GQM V L ELL+ RLPRPD CP E+Y +M CW + RP+F +L + + + Sbjct 1071 GQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM 1130 Query 1177 QG 1178 G Sbjct 1131 AG 1132 >sp|Q62689|JAK2_RAT Tyrosine-protein kinase JAK2 OS=Rattus norvegicus OX=10116 GN=Jak2 PE=1 SV=1 Length=1132 Score = 1139 bits (2947), Expect = 0.0, Method: Composition-based stats. Identities = 434/1196 (36%), Positives = 630/1196 (53%), Gaps = 131/1196 (11%) Query 16 GDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFA 75 G+ L+V L+ + ++ F AEE+C+ + GITP N+FA Sbjct 27 GNANSVKQTEPVLQVYLYHSLGQAEGDYLKFPNGEYVAEEICVAASKACGITPVYHNMFA 86 Query 76 LFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSD 135 L ++W PPNH+ I + +RIRFYF +W+ YR G Sbjct 87 LMSETERIWYPPNHVFHIDESTRHNILYRIRFYFPHWYCSGSNR--TYRYGVSRG----- 139 Query 136 QTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLA 195 LLD YLF Q +H+FV+ + H + E LGMA L + +A Sbjct 140 ---AEAPLLDDFVMSYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLDMMRIA 190 Query 196 LRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMV 255 V S+K +P+ R I+ + LTR R+R FRRF++ F + + + + Sbjct 191 KEKDQTPLAVYNSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNL 250 Query 256 MVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHE 315 +KYL LE L F TE+ V E Sbjct 251 KLKYLINLETLQSAFYTEQFEVKESARGPSGEE-----------------------IFAT 287 Query 316 VLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWA 375 +++TG GGIQW S G++ ++ ++ Sbjct 288 IIITGNGGIQW---------------SRGKHKESETLTEQD-----------------LQ 315 Query 376 YFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRL 426 +CDF DI V +K+ V++H+QD K LE+ L S ALSFVSL+DGY+RL Sbjct 316 LYCDFPDIIDVSIKQANQECSTESRVVTVHKQDGKVLEIELSSLKEALSFVSLIDGYYRL 375 Query 427 TADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRL 483 TAD+ HYLC EVAPP ++ +I HGP+ F +KL+ + GLY++ S + Sbjct 376 TADAHHYLCKEVAPPAVLENIHSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKY 435 Query 484 ILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDD 543 LT A + + + K ++G + L G R+F S+++L Q +R+ Sbjct 436 FLTFAVERENVIEYKHCLITK----NENGEYNLSGTKRNFSSLKDLLNCYQMETVRSDSI 491 Query 544 CFSLRRCCLPQPGETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEITQLSHL 595 F +CC P+P + SNL++ R S R N++Q+ FH++ +++ L Sbjct 492 IFQFTKCCPPKPKDKSNLLVFRTNGVSDVQLSPTLQRHNNVNQMVFHKIRNEDLIFNESL 551 Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655 GQGT T +++G R G E V+LKVLD +H + + +F Sbjct 552 GQGTFTKIFKGVRREVGDYGQLH-----------------ETEVLLKVLDKAHRNYSESF 594 Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715 +E AS+MSQ+SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+ VA Sbjct 595 FEAASMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLGVA 654 Query 716 QQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREERVE 774 +QLA A+ +LE K+L+HGNVC +NILL G PFIKLSDPG+ + L ++ E Sbjct 655 KQLAWAMHFLEEKSLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQE 714 Query 775 RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834 RIPW+ PEC+ +L+ A DKW FG TL EIC G+ PL + K FY+ +H+LP Sbjct 715 RIPWVPPECI-ENPKNLTLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDKHQLP 773 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA-------- 886 P +LA L + C+ YEP RP+FR ++RDL L + + + Sbjct 774 APKWTELANLINTCMDYEPDFRPAFRAVIRDLNSLFTPDYELLTENDMLPNMRIGALGFS 833 Query 887 -----SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L +H Sbjct 834 GAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTEEHL 892 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQ 999 +++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I + Sbjct 893 RDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKK 952 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 LL + QIC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V+E Sbjct 953 LLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKE 1012 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQGQ 1118 G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG QGQ Sbjct 1013 PGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDKQGQ 1072 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 M V L ELL+ RLPRP+ CP E+Y +M CW + RP+F +L + + + Sbjct 1073 MIVFHLIELLKNNGRLPRPEGCPDEIYVIMTECWNNNVNQRPSFRDLSLRVDQIRD 1128 >sp|O19064|JAK2_PIG Tyrosine-protein kinase JAK2 OS=Sus scrofa OX=9823 GN=JAK2 PE=2 SV=1 Length=1131 Score = 1138 bits (2944), Expect = 0.0, Method: Composition-based stats. Identities = 432/1198 (36%), Positives = 634/1198 (53%), Gaps = 132/1198 (11%) Query 15 VGDGAQPMAAMGG-LKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNL 73 + A + + L+V L+ + ++ F AEE+C+ + GITP ++ Sbjct 25 IPGNANSVKQIDPVLQVYLYHSLGKAEGDYLKFPAGEYVAEEICVAASKACGITPVYHSM 84 Query 74 FALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEAS 133 FAL + ++W PPNH+ + + +RIRFYF W+ YR G Sbjct 85 FALMNETERIWYPPNHVFHVDESTRHNVLYRIRFYFPYWYCNGSNR--TYRHGISRG--- 139 Query 134 SDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCH 193 LLD YLF Q +H+F+ + H + E LGMA L + Sbjct 140 -----AEAPLLDDFVMSYLFAQWRHDFLYGWVKI------PVTHETQEECLGMAVLDMMR 188 Query 194 LALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQ 253 +A ++ S+K +P+ R I+ + LTR R+R FRRF+ F + + + Sbjct 189 IAKEKDQTPLDIYSSVSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQFSHCKATAR 248 Query 254 MVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPT 313 + +KYL LE L F TE+ V +PG + Sbjct 249 NLKLKYLINLETLQSAFYTEQFEVK-----------------------EPGRGPSGEEIF 285 Query 314 HEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPL 373 +++TG GGIQW S G++ ++ ++ Sbjct 286 ATIIITGNGGIQW---------------SRGKHKESETLTEQD----------------- 313 Query 374 WAYFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYF 424 +CDF DI V +K+ V+IH+QD K LE+ L S ALSFVSL+DGY+ Sbjct 314 LQLYCDFPDIIDVSIKQANQEGSNESRIVTIHKQDGKSLEIELSSLREALSFVSLIDGYY 373 Query 425 RLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPY 481 RLTAD+ HYLC EVAPP ++ +I+ HGP+ F +KL+ + GL+++ S Sbjct 374 RLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKAGNQTGLFVLRCSPKDFN 433 Query 482 RLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAG 541 + LT A + + + K ++G + L G ++F ++++L Q +R+ Sbjct 434 KYFLTFAVERENVTEYKHCLITK----NENGEYNLSGTRKNFSNLKDLLNCYQMETVRSD 489 Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEITQLS 593 F +CC P+P + SNL++ R S R N++Q+ FH++ +++ Sbjct 490 SIIFQFTKCCPPKPKDKSNLLVFRTNGISDVPTSPTLQRHNNVNQMVFHKIRNEDLIFNE 549 Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LGQGT T +++G R G E V+LKVLD +H + + Sbjct 550 SLGQGTFTKIFKGVRREVGDYGQLH-----------------ETEVLLKVLDKAHRNYSE 592 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 +F+E AS+MSQ+SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+ Sbjct 593 SFFEAASMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLE 652 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREER 772 VA+QLA A+ +LE K L+HGNVC +NILL G PFIKLSDPG+ + L ++ Sbjct 653 VAKQLAWAMHFLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDIL 712 Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832 ERIPW+ PEC+ +L+ A DKW FG TL EIC G+ PL + K FY+ +H+ Sbjct 713 QERIPWVPPECI-ENPKNLNLATDKWSFGTTLWEICSGGDKPLNALDSQRKLQFYEDRHQ 771 Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS----- 887 LP P +LA L + C+ YEP RPSFR I+RDL L + + + Sbjct 772 LPAPKWTELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALG 831 Query 888 --------DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L + Sbjct 832 FSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTEE 890 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGL 997 H +++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I Sbjct 891 HLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDH 950 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 +LL + QIC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+V Sbjct 951 KKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKV 1010 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-AQ 1116 +E G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG Q Sbjct 1011 KEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQ 1070 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 GQM V L ELL+ RLPRPD CP E+Y +M CW + RP+F +L + + + Sbjct 1071 GQMIVFHLIELLKNNGRLPRPDGCPDEIYIIMTECWNNNVNQRPSFRDLALRVDQIRD 1128 >sp|Q62120|JAK2_MOUSE Tyrosine-protein kinase JAK2 OS=Mus musculus OX=10090 GN=Jak2 PE=1 SV=3 Length=1132 Score = 1131 bits (2925), Expect = 0.0, Method: Composition-based stats. Identities = 435/1199 (36%), Positives = 632/1199 (53%), Gaps = 134/1199 (11%) Query 15 VGDGAQPMAAMGGLK--VLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFN 72 + A + + + L H G GE ++ F AEE+C+ + GITP N Sbjct 25 IPGSANSVKQIEPVLQVYLYHSLGQAEGE-YLKFPSGEYVAEEICVAASKACGITPVYHN 83 Query 73 LFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEA 132 +FAL ++W PPNH+ I + +RIRFYF +W+ YR G Sbjct 84 MFALMSETERIWYPPNHVFHIDESTRHDILYRIRFYFPHWYCSGS--SRTYRYGVSRG-- 139 Query 133 SSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLC 192 LLD YLF Q +H+FV+ + H + E LGMA L + Sbjct 140 ------AEAPLLDDFVMSYLFAQWRHDFVHGWIKV------PVTHETQEECLGMAVLDMM 187 Query 193 HLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQ 252 +A V S+K +P+ R I+ + LTR R+R FRRF++ F + + Sbjct 188 RIAKEKDQTPLAVYNSVSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATA 247 Query 253 QMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPP 312 + + +KYL LE L F TE+ V E Sbjct 248 RNLKLKYLINLETLQSAFYTEQFEVKESARGPSGEE-----------------------I 284 Query 313 THEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREP 372 +++TG GGIQW S G++ ++ ++ Sbjct 285 FATIIITGNGGIQW---------------SRGKHKESETLTEQD---------------- 313 Query 373 LWAYFCDFRDITHVVLKE---------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGY 423 +CDF DI V +K+ V++H+QD K LE+ L S ALSFVSL+DGY Sbjct 314 -VQLYCDFPDIIDVSIKQANQECSNESRIVTVHKQDGKVLEIELSSLKEALSFVSLIDGY 372 Query 424 FRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHP 480 +RLTAD+ HYLC EVAPP ++ +I HGP+ F +KL+ + GLY++ S Sbjct 373 YRLTADAHHYLCKEVAPPAVLENIHSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDF 432 Query 481 YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA 540 + LT A + + + K ++G + L G R+F ++++L Q +R+ Sbjct 433 NKYFLTFAVERENVIEYKHCLITK----NENGEYNLSGTKRNFSNLKDLLNCYQMETVRS 488 Query 541 GDDCFSLRRCCLPQPGETSNLIIMRGARASP--------RTLNLSQLSFHRVDQKEITQL 592 F +CC P+P + SNL++ R S R N++Q+ FH++ +++ Sbjct 489 DSIIFQFTKCCPPKPKDKSNLLVFRTNGISDVQISPTLQRHNNVNQMVFHKIRNEDLIFN 548 Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 LGQGT T +++G R G + V+LKVLD +H + + Sbjct 549 ESLGQGTFTKIFKGVRREVGDYGQLH-----------------KTEVLLKVLDKAHRNYS 591 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 +F+E AS+MSQ+SH HL +GVCV G ENI+V E+V+ G LD +L++ + + + WK+ Sbjct 592 ESFFEAASMMSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKL 651 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILL-ARLGLAEGTSPFIKLSDPGVGLGALSREE 771 VA+QLA A+ +LE K+L+HGNVC +NILL G PFIKLSDPG+ + L ++ Sbjct 652 GVAKQLAWAMHFLEEKSLIHGNVCAKNILLIREEDRRTGNPPFIKLSDPGISITVLPKDI 711 Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 ERIPW+ PEC+ +L+ A DKW FG TL EIC G+ PL + K FY+ +H Sbjct 712 LQERIPWVPPECI-ENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDKH 770 Query 832 RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA----- 886 +LP P +LA L + C+ YEP RP+FR ++RDL L + + + Sbjct 771 QLPAPKWTELANLINNCMDYEPDFRPAFRAVIRDLNSLFTPDYELLTENDMLPNMRIGAL 830 Query 887 --------SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 DPT F +R+LK ++ LG+G+FG V + YDP D TGE+VAVK L Sbjct 831 GFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL-QHSTE 889 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IG 996 +H +++EI+IL++L H++I+KYKG C G ++L+L+MEY+P GSLRDYL +H I Sbjct 890 EHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERID 949 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 +LL + QIC+GM YL + YIHRDLA RN+L++N+ VKIGDFGL K +P+ EYY+ Sbjct 950 HKKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYK 1009 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI-A 1115 V+E G+SP+FWYAPE L E KF ASDVWSFGV LYEL T+ + S+SPP +F+ +IG Sbjct 1010 VKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDK 1069 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 QGQM V L ELL+ RLPRP+ CP E+Y +M CW S RP+F +L + + + Sbjct 1070 QGQMIVFHLIELLKSNGRLPRPEGCPDEIYVIMTECWNNNVSQRPSFRDLSLRVDQIRD 1128 >sp|Q62137|JAK3_MOUSE Tyrosine-protein kinase JAK3 OS=Mus musculus OX=10090 GN=Jak3 PE=1 SV=2 Length=1100 Score = 1036 bits (2679), Expect = 0.0, Method: Composition-based stats. Identities = 440/1171 (38%), Positives = 591/1171 (50%), Gaps = 147/1171 (13%) Query 44 VTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYF 103 ++FS AE++C+ A GI P +LFAL W PP+HI I + +L + Sbjct 41 LSFSFGDYLAEDLCVRAAKACGILPVYHSLFALATEDFSCWFPPSHIFCIEDVDTQVLVY 100 Query 104 RIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVND 163 R+RFYF +W G+ +R G S+ +LD E+LF Q + + V+ Sbjct 101 RLRFYFPDWFGLE----TCHRFGLRKDLTSA--------ILDLHVLEHLFAQHRSDLVSG 148 Query 164 VASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHI 223 + LS +E + E L +A L L +A E+ K S+K C+P S R I Sbjct 149 RLPV-GLSMKE-----QGEFLSLAVLDLAQMAREQAQRPGELLKTVSYKACLPPSLRDVI 202 Query 224 RQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLL 283 + + +TR R+R LR + + +M KY+ LERL P TE V L Sbjct 203 QGQNFVTRRRIRRTVVLALRRVVACQADRYALMAKYILDLERLHPAATTETFRVG----L 258 Query 284 AQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSS 343 A+ EP +R V G GI W ++E Sbjct 259 PGAQEEPGLLR-----------------------VAGDNGISWSSGDQE----------- 284 Query 344 GRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKE----------HCV 393 L+ FCDF +I V +K+ V Sbjct 285 -----------------------------LFQTFCDFPEIVDVSIKQAPRVGPAGEHRLV 315 Query 394 SIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHG 453 ++ R D LE P ALSFV+LVDGYFRL DS HY C EVAPPRL+ + HG Sbjct 316 TVTRMDGHILEAEFPGLPEALSFVALVDGYFRLICDSRHYFCKEVAPPRLLEEEAELCHG 375 Query 454 PLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQ 510 P+ F KL+ G Y++ S +LT ++ + +R+ P Sbjct 376 PITLDFAIHKLKAAGSLPGTYILRRSPQDYDSFLLTACVQTPLGPDYKGCLIRQDP---- 431 Query 511 DGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGA--- 567 GAF L G + S+REL AA LR +L CC P+P E SNLI++R Sbjct 432 SGAFSLVGLSQPHRSLRELLAACWNSGLRVDGAALNLTSCCAPRPKEKSNLIVVRRGCTP 491 Query 568 ----RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 SP L+QLSFH + + +LG G+ T ++ GR R G+ + Sbjct 492 APAPGCSPSCCALTQLSFHTIPTDSLEWHENLGHGSFTKIFRGRRREVVDGETHDS---- 547 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 V+LKV+D H + +F E ASLMSQVS+ HL +HGVC+ G Sbjct 548 --------------EVLLKVMDSRHRNCMESFLEAASLMSQVSYPHLVLLHGVCMAGDS- 592 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 IMV E+V G +D++LR+ V +WK+ V +QLA AL+YLE+K L HGNV R +LLA Sbjct 593 IMVQEFVYLGAIDMYLRKRGHLVSASWKLQVTKQLAYALNYLEDKGLPHGNVSARKVLLA 652 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 R G +G PFIKLSDPGV LS E +RIPW+APECL A +L DKWGFGAT Sbjct 653 REG-GDGNPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQE-AQTLCLEADKWGFGAT 710 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 E+ G A + S P++K FY+ Q +LP +LA L +QC+ Y+P +RPSFR IL Sbjct 711 TWEVFSGGPAHITSLEPAKKLKFYEDQGQLPALKWTELAGLITQCMAYDPGRRPSFRAIL 770 Query 864 RDLTRLQPHNL--------------ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 RDL L + ++ DP +F +R+LK I LG+G+FG Sbjct 771 RDLNGLITSDYELLSDPTPGIPSPRDELCGGAQLYACQDPAIFEERHLKYISLLGKGNFG 830 Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 V L YDP D TG +VAVK L GP + +++EI IL+ L+ + I+KY+G Sbjct 831 SVELCRYDPLGDNTGPLVAVKQL-QHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGP 889 Query 970 GEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027 G +SL+LVMEY+P G LRD+L RH + +LLLFA QIC+GM YL A+ +HRDLAAR Sbjct 890 GRQSLRLVMEYLPSGCLRDFLQRHRARLHTDRLLLFAWQICKGMEYLGARRCVHRDLAAR 949 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 N+L++++ VKI DFGLAK +P G +YY VRE G SP+FWYAPE L + F SDVWSF Sbjct 950 NILVESEAHVKIADFGLAKLLPLGKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSF 1009 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 GV LYEL T+CD S SP +FL ++G + + RL ELL G RLP P CP EV L Sbjct 1010 GVVLYELFTYCDKSCSPSAEFLRMMGPEREGPPLCRLLELLAEGRRLPPPPTCPTEVQEL 1069 Query 1148 MKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 M+ CW RP F L P L + G Sbjct 1070 MQLCWAPSPHDRPAFGTLSPQLDALWRGRPG 1100 >sp|P52333|JAK3_HUMAN Tyrosine-protein kinase JAK3 OS=Homo sapiens OX=9606 GN=JAK3 PE=1 SV=2 Length=1124 Score = 1036 bits (2679), Expect = 0.0, Method: Composition-based stats. Identities = 444/1200 (37%), Positives = 612/1200 (51%), Gaps = 146/1200 (12%) Query 23 AAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQ 82 G L VLL GPG + ++FS AE++C+ A GI P +LFAL Sbjct 21 TEAGALHVLLPARGPGPPQ-RLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATEDLS 79 Query 83 VWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQ 142 W PP+HI + ++ +L +RIRFYF NW G+ +R G AS+ Sbjct 80 CWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLE----KCHRFGLRKDLASA-------- 127 Query 143 LLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPL 202 +LD E+LF Q + + V+ + LS +E + E L +A L L +A Sbjct 128 ILDLPVLEHLFAQHRSDLVSGRLPV-GLSLKE-----QGECLSLAVLDLARMAREQAQRP 181 Query 203 EEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLAT 262 E+ K S+K C+P S R I+ S +TR R+R RR LR + + +M KY+ Sbjct 182 GELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMD 241 Query 263 LERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTG 322 LERL P E V + V G G Sbjct 242 LERLDPAGAAETFHVGLPGA------------------------LGGHDGLGLLRVAGDG 277 Query 323 GIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRD 382 GI W E+EV FCDF + Sbjct 278 GIAWTQGEQEV----------------------------------------LQPFCDFPE 297 Query 383 ITHVVLKE----------HCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSH 432 I + +K+ V++ R DN+ LE P ALSFV+LVDGYFRLT DS H Sbjct 298 IVDISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQH 357 Query 433 YLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQ 489 + C EVAPPRL+ + + HGP+ F KL+ G Y++ S +LTV Sbjct 358 FFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCV 417 Query 490 RSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRR 549 ++ + +R+ P G F+L G R S+REL A L +L Sbjct 418 QNPLGPDYKGCLIRRSPT----GTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTS 473 Query 550 CCLPQPGETSNLIIMRGARASPRT--------LNLSQLSFHRVDQKEITQLSHLGQGTRT 601 CC+P+P E SNLI+++ + P + LSQ++FH++ + +LG G+ T Sbjct 474 CCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFT 533 Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL 661 +Y G G+ ++ V+LKV+D H + +F E ASL Sbjct 534 KIYRGCRHEVVDGE------------------ARKTEVLLKVMDAKHKNCMESFLEAASL 575 Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA 721 MSQVS+ HL +HGVC+ G MV E+V G +D++LR+ VP +WK+ V +QLA A Sbjct 576 MSQVSYRHLVLLHGVCMAGDST-MVQEFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYA 634 Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP 781 L+YLE+K L HGNV R +LLAR G A+G+ PFIKLSDPGV LS E +RIPW+AP Sbjct 635 LNYLEDKGLPHGNVSARKVLLAREG-ADGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAP 693 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL 841 ECL A +LS DKWGFGAT+ E+ P+ + P++K FY+ + +LP P +L Sbjct 694 ECLRE-AQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQFYEDRQQLPAPKWTEL 752 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL--------------ADVLTVNPDSPAS 887 A L QC+ YEP QRPSFR ++RDL L + + Sbjct 753 ALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALAPRDGLWNGAQLYACQ 812 Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 DPT+F +R+LK I LG+G+FG V L YDP D TG +VAVK L GP + +++E Sbjct 813 DPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQL-QHSGPDQQRDFQRE 871 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQ 1005 I IL+ L+ + I+KY+G G +SL+LVMEY+P G LRD+L RH + ++LLL++ Sbjct 872 IQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSS 931 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 QIC+GM YL ++ +HRDLAARN+L++++ VKI DFGLAK +P +YY VRE G SP+ Sbjct 932 QICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPI 991 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 FWYAPE L + F SDVWSFGV LYEL T+CD S SP +FL ++G + + RL Sbjct 992 FWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLL 1051 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 ELLE G+RLP P CP EV+ LMK CW RP+F L P L + +G F+ Sbjct 1052 ELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDMLWSGSRGCETHAFT 1111 Score = 197 bits (500), Expect = 6e-50, Method: Composition-based stats. Identities = 68/331 (21%), Positives = 111/331 (34%), Gaps = 54/331 (16%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +++ + +S LG+G +V E V +K L Sbjct 818 EERHLKYISQLGKGNFGSV--------------------ELCRYDPLGDNTGALVAVKQL 857 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEHGPLDVWLRRE 702 S D F ++ + + GV +V EY+ G L +L+R Sbjct 858 QHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRH 917 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 R + + ++ + Q+ + YL ++ VH ++ RNIL+ + +K++D G+ Sbjct 918 RARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILV-------ESEAHVKIADFGL 970 Query 763 G-LGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD----- 810 L L ++ V R I W APE L S D W FG L E+ Sbjct 971 AKLLPLDKDYYVVREPGQSPIFWYAPESLSDNI--FSRQSDVWSFGVVLYELFTYCDKSC 1028 Query 811 ---GEAPLQSRSPSEKEHFYQR------QHRLP-EPSCP-QLATLTSQCLTYEPTQRPSF 859 E + + RLP P+CP ++ L C P RPSF Sbjct 1029 SPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSF 1088 Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 + L L + P Sbjct 1089 SALGPQLDMLWSGSRGCETHAFTAHPEGKHH 1119 >sp|Q63272|JAK3_RAT Tyrosine-protein kinase JAK3 OS=Rattus norvegicus OX=10116 GN=Jak3 PE=2 SV=2 Length=1100 Score = 1025 bits (2649), Expect = 0.0, Method: Composition-based stats. Identities = 434/1167 (37%), Positives = 593/1167 (51%), Gaps = 147/1167 (13%) Query 44 VTFSESSLTAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYF 103 ++FS AE++C+ A GI P +LFAL W PP+HI I + +L + Sbjct 41 LSFSFGDYLAEDLCVRAAKACGILPVYHSLFALATEDLSCWFPPSHIFSIEDVDTQVLVY 100 Query 104 RIRFYFRNWHGMNPREPAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVND 163 R+RFYF W G+ +R G S+ +LD E+LF Q + + V+ Sbjct 101 RLRFYFPGWFGLE----TCHRFGLHKDLTSA--------ILDVHVLEHLFAQHRSDLVSG 148 Query 164 VASLWELSTEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHI 223 + LS ++ + E L +A L L +A + E+ K S+K C+P S R I Sbjct 149 RLPV-GLSLKD-----QGEFLSLAVLDLAQMARKQAQRPGELLKSVSYKACLPPSLRDLI 202 Query 224 RQHSALTRLRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLL 283 + S +TR R+R + LR + + +M KY+ LERL P TE V L Sbjct 203 QGQSFVTRRRIRRTVVQALRRVVACQADRYALMAKYILDLERLHPAATTESFLVG----L 258 Query 284 AQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSS 343 A+ EP +R VTG GI W ++E Sbjct 259 PGAQEEPGCLR-----------------------VTGDNGIAWSSKDQE----------- 284 Query 344 GRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKE----------HCV 393 L+ FCDF +I V +K+ V Sbjct 285 -----------------------------LFQTFCDFPEIVDVSIKQAPRVGPAGEHRLV 315 Query 394 SIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHG 453 +I R D LE P ALSFV+LVDGYFRL DS H+ C EVAPPRL+ + HG Sbjct 316 TITRMDGHILEAEFPGLPEALSFVALVDGYFRLICDSRHFFCKEVAPPRLLEEEAELCHG 375 Query 454 PLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQ 510 P+ F KL+ G Y++ S +LT ++ + +R+ P Sbjct 376 PITLDFAIHKLKAAGSLPGSYILRRSPQDYDSFLLTACVQTPLGPDYKGCLIRQDP---- 431 Query 511 DGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARA- 569 GAF L G + S++EL A L+ +L CC+P+P E SNLI++R R Sbjct 432 SGAFSLVGLSQLHRSLQELLTACWHSGLQVDGTALNLTSCCVPRPKEKSNLIVVRRGRNP 491 Query 570 ------SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 SP L++LSFH + + +LG G+ T ++ G R G+ Sbjct 492 TPAPGHSPSCCALTKLSFHTIPADSLEWHENLGHGSFTKIFHGHRREVVDGETH------ 545 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 + V+LKV+D H + +F E ASLMSQVS+ HL +HGVC+ G Sbjct 546 ------------DTEVLLKVMDSRHQNCMESFLEAASLMSQVSYPHLVLLHGVCMAGDS- 592 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 IMV E+V G +D +LR+ VP +WK+ V +QLA AL+YLE+K L HGNV R +LLA Sbjct 593 IMVQEFVYLGAIDTYLRKRGHLVPASWKLQVTKQLAYALNYLEDKGLPHGNVSARKVLLA 652 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 R G+ +G PFIKLSDPGV LS E +RIPW+APECL A +L+ DKWGFGAT Sbjct 653 REGV-DGNPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQE-AGTLNLEADKWGFGAT 710 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 E+ + S P++K FY+ + +LP +L L +QC+ Y+P +RPSFR IL Sbjct 711 TWEVFSGAPMHITSLEPAKKLKFYEDRGQLPALKWTELEGLIAQCMAYDPGRRPSFRAIL 770 Query 864 RDLTRLQ--------------PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 RDL L P+ ++ DP +F +R+LK I LG+G+FG Sbjct 771 RDLNGLITSDYELLSDPTPGIPNPRDELCGGAQLYACQDPAIFEERHLKYISLLGKGNFG 830 Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 V L YDP D TG +VAVK L GP+ + +++EI IL+ L+ + I+KY+G Sbjct 831 SVELCRYDPLGDNTGPLVAVKQL-QHSGPEQQRDFQREIQILKALHCDFIVKYRGVSYGP 889 Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027 G +SL+LVMEY+P G LRD+L RH L +LLLFA QIC+GM YL A+ +HRDLAAR Sbjct 890 GRQSLRLVMEYLPSGCLRDFLQRHRARLHNDRLLLFAWQICKGMEYLGARRCVHRDLAAR 949 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 N+L++++ VKI DFGLAK +P G +YY VRE G SP+FWYAPE L + F SDVWSF Sbjct 950 NILVESEAHVKIADFGLAKLLPLGKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSF 1009 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 GV LYEL T+ D S SP T+FL ++G + + L ELL G RLP P CP EV L Sbjct 1010 GVVLYELFTYSDKSCSPSTEFLRMMGPEREGSPLCHLLELLAEGRRLPPPSTCPTEVQEL 1069 Query 1148 MKNCWETEASFRPTFENLIPILKTVHE 1174 M+ CW RP F+ L P L + Sbjct 1070 MQLCWSPNPQDRPAFDTLSPQLDALWR 1096 >sp|Q24592|JAK_DROME Tyrosine-protein kinase hopscotch OS=Drosophila melanogaster OX=7227 GN=hop PE=1 SV=2 Length=1177 Score = 416 bits (1068), Expect = 1e-124, Method: Composition-based stats. Identities = 242/1221 (20%), Positives = 422/1221 (35%), Gaps = 167/1221 (14%) Query 16 GDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEVCIHIAHKVGITPPCFNLFA 75 G +Q + G + ++ ++ EE+C + ++GI P L+ Sbjct 35 GTSSQSIHTNDGTIRVFNFTTGE-----FERFHPNMLCEEICNTMCRQLGIAPIAQLLYG 89 Query 76 LFDAQAQ-----------VWLPPNHILEIPRDASLMLYFRIRFYFRNWHGMNPREPAVYR 124 + + W P L L+ FR+RF Sbjct 90 IREHSTSRRPSPLVRLDLTWCLPGERLNCQ----LVYCFRMRFRVP-------------- 131 Query 125 CGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHFKNESL 184 + ++L+D S ++L+ Q +++ + E K++S Sbjct 132 -----------ELDSQLELIDGRSHKFLYRQMRYDMRTEQIP------EIRYPEHKDKST 174 Query 185 GMAFLHLCHLALRHGIPLEEVAK-KTSFKDCIPRSFRRHIRQHSALTRLRLRNVFRRFLR 243 G+A + + + + + +K +P S R HS ++R VFR Sbjct 175 GLAVMDMLIDDQEQSEDQQAMRSIEKLYKLYLPPSL---WRAHSFFVGSKIREVFR---- 227 Query 244 DFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPC---------YIR 294 + LS + + Y+ + LAP + TE+ C ++ L E + Sbjct 228 SLKANSLSVERLKWHYVHQVSHLAPTYMTEQF-TCTVQYLPNEEVARGSGPIGTSLAHST 286 Query 295 DSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGK 354 + + S T+ V + G+G + + G P SL Sbjct 287 STLASSGSTNTLSTLTTNTNSVALGGSG-----KKAKRRSTSGGIDVYVRVFPHDSLEPG 341 Query 355 KAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAAL 414 A I ++ V + K E+ + Sbjct 342 LKVARVTSEATLKWILVGAVEGIFMISKINDTSVRLEIVGLP----KGYEMQFQTEKEMK 397 Query 415 SFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLY 471 SF+S + Y RL++ LCH P L HGP+ + KL G Y Sbjct 398 SFISYLGIYIRLSSKWMQDLCHSYRTPSLEELSSLHCHGPIGGAYSLMKLHENGDKCGSY 457 Query 472 LIHWSTSHPYRLILTV-AQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELG 530 ++ + + + + + F I ++D + L S+ + + Sbjct 458 IVRECDREYNIYYIDINTKIMAKKTDQERCKTETFRIVRKDSQWKL-----SYNNGEHVL 512 Query 531 AALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASP--RTLNLSQLSFHRVDQKE 588 +L D R + + L+++ L LS+ R + + Sbjct 513 NSLHEVAHIIQADSPDRYRIPASKYDKPPLLLLLLPKNLKAKKTDLQLSEAELQRRNPQI 572 Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 + L + + ++G M + +++ V +K+L Sbjct 573 FNPRTDL-----------QWYPDSISLSDDGMMFTMRGDWIQQSPVKDVSVTMKMLKSDG 621 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 + + F+ A S + ++G+ MV EY +GPL+ +L +V + Sbjct 622 N--FMEFFRLAQTWSLIQSPQFLKLYGL-TLADPYTMVMEYSRYGPLNKFLH-SMPNVTL 677 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + + L + YLE+ ++H + N+ + + K+SDPG Sbjct 678 HCLLDLMHGLVRGMHYLEDNKIIHNYIRCSNLYVTKYD-PNSYVLDAKISDPG-----YP 731 Query 769 REERVERIPWLAPECLPG-GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 R R PW+ + A W F T+ EI + L + + Sbjct 732 RPYRESDSPWIPVKYYRNLQAAKTDQFAQLWAFATTIYEIFSRCKEDLSTLRQEQLLRQK 791 Query 828 QRQ----HRLPEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN- 881 L + CP + + + T+R S I L ++ L + + Sbjct 792 NLDGNILKMLDQDICPAPIFETIMDGWSDDETKRFSHHDIFSRLNTIKAEILPNYMPPPE 851 Query 882 -------------------------PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916 T + +G GH+G V Sbjct 852 IATNGTGDETVIDRSDIPFLPFPRSNMLMVIPLTSECRVIYNMENMIGRGHYGTVYKGHL 911 Query 917 DPTNDGT-GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 + + E VA+K L Q + + +EI I+RTL H +I+K+K EKS Sbjct 912 EFNDKDQPREQVAIKMLN---TMQVSTDFHREIGIMRTLSHPNIVKFKYW----AEKSHC 964 Query 976 LVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033 ++MEY+ GS YL ++ +L+ FA I GM YL IHRDLAARN+L+D+ Sbjct 965 IIMEYLQSGSFDIYLRFTAPNLNNPRLVSFALDIANGMKYLSDMGLIHRDLAARNILVDH 1024 Query 1034 DRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 + VKI DFGLA YY + D P+ WY+PE + +F SDVWS+GVT Sbjct 1025 NGDGDCVKISDFGLA-QFANSDGYYYAKSKRDIPIRWYSPEAISTCRFSSYSDVWSYGVT 1083 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 L+E+ + + P Q + L+ GERL RP CP +Y LM+ Sbjct 1084 LFEMFSRGEEPNLVPI-----------QTSQEDFLNRLQSGERLNRPASCPDFIYDLMQL 1132 Query 1151 CWETEASFRPTFENLIPILKT 1171 CW RP+F ++ I+ Sbjct 1133 CWHATPRSRPSFATIVDIITR 1153 Score = 214 bits (545), Expect = 3e-55, Method: Composition-based stats. Identities = 70/309 (23%), Positives = 119/309 (39%), Gaps = 40/309 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + +G+G VY+G L P E +V +K+L+ Sbjct 894 MENMIGRGHYGTVYKGHLEFNDKDQPRE-------------------QVAIKMLN--TMQ 932 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 ++ F+ +M +SH ++ ++ EY++ G D++LR ++ Sbjct 933 VSTDFHREIGIMRTLSHPNIVKFK-YWAEKSH-CIIMEYLQSGSFDIYLRFTAPNLNNPR 990 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + A +A+ + YL + L+H ++ RNIL+ G + +K+SD G+ A S Sbjct 991 LVSFALDIANGMKYLSDMGLIHRDLAARNILVDHNGDGD----CVKISDFGLAQFANSDG 1046 Query 771 ERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + I W +PE + S+ D W +G TL E+ GE P + +E Sbjct 1047 YYYAKSKRDIPIRWYSPEAISTC--RFSSYSDVWSYGVTLFEMFSRGEEPNLVPIQTSQE 1104 Query 825 HFYQR---QHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 F R RL P + L C P RPSF TI+ +TR + Sbjct 1105 DFLNRLQSGERLNRPASCPDFIYDLMQLCWHATPRSRPSFATIVDIITREVATKVTHPTD 1164 Query 880 VNPDSPASD 888 + P Sbjct 1165 GHQSPPNQP 1173 Score = 89.7 bits (221), Expect = 1e-16, Method: Composition-based stats. Identities = 50/260 (19%), Positives = 92/260 (35%), Gaps = 41/260 (16%) Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 V +K LK+D + + + +K G +VMEY G L Sbjct 612 VTMKMLKSDGNFM---EFFRLAQTWSLIQSPQFLKLYGLTL---ADPYTMVMEYSRYGPL 665 Query 987 RDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND------RLVKI 1039 +L ++ L LL + GM YL IH + N+ + KI Sbjct 666 NKFLHSMPNVTLHCLLDLMHGLVRGMHYLEDNKIIHNYIRCSNLYVTKYDPNSYVLDAKI 725 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASD----VWSFGVTLYELL 1095 D G + YR + PV +Y +D +W+F T+YE+ Sbjct 726 SDPGYPR-------PYRESDSPWIPVKYY------RNLQAAKTDQFAQLWAFATTIYEIF 772 Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155 + C S + L + + + ++L++ D CP ++ + + W + Sbjct 773 SRCKEDLSTLRQEQLL----RQKNLDGNILKMLDQ-------DICPAPIFETIMDGWSDD 821 Query 1156 ASFRPTFENLIPILKTVHEK 1175 + R + ++ L T+ + Sbjct 822 ETKRFSHHDIFSRLNTIKAE 841 >sp|P42688|SRK2_SPOLA Tyrosine-protein kinase SRK2 (Fragment) OS=Spongilla lacustris OX=6055 GN=SRK2 PE=2 SV=1 Length=362 Score = 323 bits (827), Expect = 3e-99, Method: Composition-based stats. Identities = 90/402 (22%), Positives = 149/402 (37%), Gaps = 67/402 (17%) Query 470 LYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVREL 529 +L+ S S P L++ Q D ++ R+RK D F ++++L Sbjct 1 TFLVRESESKPGDYSLSI----QDGDNVKHYRIRKL-----DEGGFFITRRAVFNTLKDL 51 Query 530 GAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEI 589 Q + C +LR+ C P +L + + + I Sbjct 52 VQYYQNE---SDGLCVNLRQPCRPLERPQIDL-------------SHKTKDMWEISRDSI 95 Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 T + LG G VY+G V +K L Sbjct 96 TLIRKLGAGQFGEVYQGLW-------------------------NNSTPVAVKTLKAGTM 130 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 A AF A +M ++ H L ++ VC +G ++TE + G L +L+ E G + + Sbjct 131 QPA-AFLAEAQIMKKLRHPKLIQLYAVCTQGEPVYIITELMSKGSLLDYLQGEAGALKLP 189 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 + +A Q+A+ ++YLE N +H ++ RNIL+ G + K++D G+ +S Sbjct 190 QLIDMAAQVAAGMAYLELHNYIHRDLAARNILV-------GDNNICKVADFGLARLIVSD 242 Query 770 EERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + I W APE N S D W FG + E+ G P S +E Sbjct 243 DYNATEGAKFPIKWTAPEAAL--FNRFSIKSDVWSFGILITELVTYGRIPYPGMSNAEVL 300 Query 825 HFYQRQHRLPEPSCPQ--LATLTSQCLTYEPTQRPSFRTILR 864 + +R+P P L + C P RP+F + Sbjct 301 QNLDKGYRMPCPVTTPESLYQIMLDCWKRNPADRPTFEALQW 342 Score = 275 bits (703), Expect = 9e-82, Method: Composition-based stats. Identities = 99/324 (31%), Positives = 152/324 (47%), Gaps = 27/324 (8%) Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910 + Q + + QP + ++ D + + IR LG G FG+ Sbjct 49 KDLVQYYQNESDGLCVNLRQPCRPLERPQIDLSHKTKDMWEISRDSITLIRKLGAGQFGE 108 Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970 V + N+ T VAVK LKA G + + E I++ L H +I+ C Sbjct 109 VYQGLW---NNST--PVAVKTLKA--GTMQPAAFLAEAQIMKKLRHPKLIQLYAVCTQG- 160 Query 971 EKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARN 1028 + + ++ E + GSL DYL + + L QL+ A Q+ GMAYL +YIHRDLAARN Sbjct 161 -EPVYIITELMSKGSLLDYLQGEAGALKLPQLIDMAAQVAAGMAYLELHNYIHRDLAARN 219 Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 +L+ ++ + K+ DFGLA+ + Y E P+ W APE +F SDVWSFG Sbjct 220 ILVGDNNICKVADFGLARLIVSDD--YNATEGAKFPIKWTAPEAALFNRFSIKSDVWSFG 277 Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148 + + EL+T+ I M+ + + L++G R+P P P +Y +M Sbjct 278 ILITELVTYGR--------------IPYPGMSNAEVLQNLDKGYRMPCPVTTPESLYQIM 323 Query 1149 KNCWETEASFRPTFENLIPILKTV 1172 +CW+ + RPTFE L L+ Sbjct 324 LDCWKRNPADRPTFEALQWRLEDF 347 >sp|P42690|SRK4_SPOLA Tyrosine-protein kinase isoform SRK4 OS=Spongilla lacustris OX=6055 GN=SRK1 PE=2 SV=1 Length=506 Score = 323 bits (829), Expect = 1e-97, Method: Composition-based stats. Identities = 101/430 (23%), Positives = 167/430 (39%), Gaps = 73/430 (17%) Query 448 RDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 + G + + +L G +LI S + P L+V R+R Sbjct 120 EEWFFGQVKRVDAEKQLMMPFNNLGSFLIRDSDTTPGDFSLSVRDID---------RVRH 170 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + I++ + +F S++EL A A C +L+ C+ Sbjct 171 YRIKKLENGTYFVTRRLTFQSIQELVAYYTQQ---ADGLCVNLKGPCM------------ 215 Query 565 RGARASPRTLNLSQLSF--HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 P+T LS+ + +++K+I L LG G V+EG S Sbjct 216 --VMEKPQTAGLSKQANEEWEIEKKQIKLLRGLGAGQFGEVWEGLWNGTTS--------- 264 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 V +K L P I F E AS+M Q+ H L ++ VC + Sbjct 265 ----------------VAVKTLKPGTMSI-EEFLEEASIMKQLRHPKLIQLYAVCTKEEP 307 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +VTE ++HG L +LR + + + + + Q+AS +SYLE +N +H ++ RNIL+ Sbjct 308 IYIVTELMKHGSLLEYLRGDGRSLKLPDLVDMCSQVASGMSYLEQQNYIHRDLAARNILV 367 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDK 797 G K++D G+ + I W APE + + D Sbjct 368 -------GEHKICKVADFGLARVIDEEIYEAKLGAKFPIKWTAPEAAM--YSRFTIKSDV 418 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQ 855 W FG L E+ G P + ++ Q+ +R+P P CP +L + C +P Sbjct 419 WSFGIVLYEVITYGRFPYPGMTNAQVLEQIQQSYRMPRPMGCPEKLYAIMMDCWREDPAS 478 Query 856 RPSFRTILRD 865 RP+F T+ Sbjct 479 RPTFETLSWQ 488 Score = 285 bits (729), Expect = 1e-83, Method: Composition-based stats. Identities = 99/305 (32%), Positives = 151/305 (50%), Gaps = 27/305 (9%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 + T A++ K+ +K +R LG G FG+V ++ T VAV Sbjct 213 PCMVMEKPQTAGLSKQANEEWEIEKKQIKLLRGLGAGQFGEVWEGLWNGT-----TSVAV 267 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K LK G + +E I++ L H +I+ C E+ + +V E + GSL +Y Sbjct 268 KTLKP--GTMSIEEFLEEASIMKQLRHPKLIQLYAVCTK--EEPIYIVTELMKHGSLLEY 323 Query 990 LPR--HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 L S+ L L+ Q+ GM+YL Q+YIHRDLAARN+L+ ++ K+ DFGLA+ Sbjct 324 LRGDGRSLKLPDLVDMCSQVASGMSYLEQQNYIHRDLAARNILVGEHKICKVADFGLARV 383 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + E E Y + P+ W APE +F SDVWSFG+ LYE++T+ Sbjct 384 IDE--EIYEAKLGAKFPIKWTAPEAAMYSRFTIKSDVWSFGIVLYEVITYGR-------- 433 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 MT ++ E +++ R+PRP CP ++Y +M +CW + + RPTFE L Sbjct 434 ------FPYPGMTNAQVLEQIQQSYRMPRPMGCPEKLYAIMMDCWREDPASRPTFETLSW 487 Query 1168 ILKTV 1172 L+ Sbjct 488 QLEEF 492 >sp|Q54I36|PYK3_DICDI Dual specificity protein kinase pyk3 OS=Dictyostelium discoideum OX=44689 GN=pyk3 PE=1 SV=1 Length=1338 Score = 342 bits (876), Expect = 4e-97, Method: Composition-based stats. Identities = 120/541 (22%), Positives = 213/541 (39%), Gaps = 69/541 (13%) Query 665 VSHTHLAFVHGVCVRGPENIMVTE-YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723 + H +L + G C ++ E + L + R+ + MA + +++ +AS + Sbjct 814 IQHKNLGLLVGWCGDS----IIFESFKGMNSLHDLIHRDGLKIDMALFIKISKDIASVMG 869 Query 724 YLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPEC 783 L +K++ HGN+ R+I L R + +K+S P + A ++APE Sbjct 870 LLHSKDVAHGNLTSRSIYLDRFQI-------VKVSFPKL--NATDLNNPAIEPRYMAPEM 920 Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAP--LQSRSPSEKEHFYQRQHRLPEPSCPQL 841 + +S ++D + + L E S + K + + ++P + Sbjct 921 TRMEEDQISCSIDVYAYAFVLWEALTSHLPFRKFNDISVAAKVAYENLRPKIPTSCPLII 980 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQ---------------------PHNLADVLTV 880 L ++C P+ RP+F IL+ L+ Sbjct 981 RKLINRCWAPLPSDRPTFNDILKLFDHLEGKLFFSSPGILWSLNNDQEVERELQKKERFN 1040 Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH 940 + + +G G F V L + G VA+K LK + Sbjct 1041 EITEFLRGKKEIKFDEVAIVEKVGAGSFANVFLGIW------NGYKVAIKILKNESISND 1094 Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL 1000 + +E+ L +H +++ + G C D + EY+ GSL D L I L L Sbjct 1095 -EKFIKEVSSLIKSHHPNVVTFMGACIDPP----CIFTEYLQGGSLYDVLHIQKIKLNPL 1149 Query 1001 LLF--AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 +++ + GM +LH+ +HRDL ++N+LLD + +KI DFGLA + + + Sbjct 1150 MMYKMIHDLSLGMEHLHSIQMLHRDLTSKNILLDEFKNIKIADFGLATTLSDD-----MT 1204 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 G + W +PE K + DV+SFG+ +YE+ T + L G A Sbjct 1205 LSGITNPRWRSPELTKGLVYNEKVDVYSFGLVVYEIYTGKIPFEG-------LDGTASAA 1257 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 R P CP + L+ CW ++ S RP+F ++ L+T+ K+ Sbjct 1258 KAAFE-------NYRPAIPPDCPVSLRKLITKCWASDPSQRPSFTEILTELETMKSKFIK 1310 Query 1179 Q 1179 Q Sbjct 1311 Q 1311 Score = 200 bits (508), Expect = 9e-51, Method: Composition-based stats. Identities = 60/321 (19%), Positives = 116/321 (36%), Gaps = 43/321 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + E+ + +G G+ NV+ G +V + Sbjct 1050 KEIKFDEVAIVEKVGAGSFANVFLGIW--------------------------NGYKVAI 1083 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 K+L F + S + + H ++ G C+ P + TEY++ G L L Sbjct 1084 KILKNESISNDEKFIKEVSSLIKSHHPNVVTFMGACIDPP--CIFTEYLQGGSLYDVLHI 1141 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 ++ + + L+ + +L + ++H ++ +NILL IK++D G Sbjct 1142 QKIKLNPLMMYKMIHDLSLGMEHLHSIQMLHRDLTSKNILLDEF-------KNIKIADFG 1194 Query 762 VGLGALSREERVE--RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + W +PE G + +D + FG + EI + G+ P + Sbjct 1195 LATTLSDDMTLSGITNPRWRSPELTKGLV--YNEKVDVYSFGLVVYEI-YTGKIPFEGLD 1251 Query 820 ---PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 + K F + +P L L ++C +P+QRPSF IL +L ++ + Sbjct 1252 GTASAAKAAFENYRPAIPPDCPVSLRKLITKCWASDPSQRPSFTEILTELETMKSKFIKQ 1311 Query 877 VLTVNPDSPASDPTVFHKRYL 897 + +N D + Sbjct 1312 LSFLNDLIQNPDDDYNNNLNY 1332 Score = 124 bits (310), Expect = 4e-27, Method: Composition-based stats. Identities = 52/237 (22%), Positives = 97/237 (41%), Gaps = 34/237 (14%) Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVME-YVPLGSLRDYLPRH--SIGLAQLLLFAQQICE 1009 + H+++ G C D ++ E + + SL D + R I +A + ++ I Sbjct 813 MIQHKNLGLLVGWCGDS------IIFESFKGMNSLHDLIHRDGLKIDMALFIKISKDIAS 866 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 M LH++ H +L +R++ LD ++VK+ + P + A Sbjct 867 VMGLLHSKDVAHGNLTSRSIYLDRFQIVKVS--------FPKLNATDLNNPAIEP-RYMA 917 Query 1070 PEC--LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 PE ++E + + DV+++ L+E LT S P KF ++ A ++ Sbjct 918 PEMTRMEEDQISCSIDVYAYAFVLWEALT----SHLPFRKFNDISVAA----------KV 963 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 R P CP + L+ CW S RPTF +++ + + K +P + Sbjct 964 AYENLRPKIPTSCPLIIRKLINRCWAPLPSDRPTFNDILKLFDHLEGKLFFSSPGIL 1020 >sp|P42686|SRK1_SPOLA Tyrosine-protein kinase isoform SRK1 OS=Spongilla lacustris OX=6055 GN=SRK1 PE=2 SV=1 Length=505 Score = 320 bits (821), Expect = 1e-96, Method: Composition-based stats. Identities = 97/445 (22%), Positives = 162/445 (36%), Gaps = 69/445 (16%) Query 448 RDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 + G + + L + G +LI S + P L+V + R+R Sbjct 120 EEWFLGKIKRVEAEKMLNQSFNQVGSFLIRDSETTPGDFSLSVKDQD---------RVRH 170 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + + + + + +F + EL + + C L CL + ++ Sbjct 171 YRVRRLEDGSLFVTRRSTFQILHELVDHYK---IETDGLCCKLLYPCLQAEKPQTAGLLR 227 Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 + +++ +I L LG G V+EG S Sbjct 228 QANEE------------WEIEKTQIKLLRRLGAGQFGEVWEGLWNGTTS----------- 264 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 V +K L P + F + AS+M ++ H L ++ VC + Sbjct 265 --------------VAVKTLKPGTMSV-EEFLQEASIMKRLRHPKLIQLYAVCTKEEPIY 309 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 +VTE +++G L +LR E G + + + VA Q+AS +SYLE +N +H ++ RNIL+ Sbjct 310 IVTELMKYGSLLEYLRGEDGVLKIEQLVDVAAQVASGMSYLEQQNYIHRDLAARNILVGE 369 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWG 799 G+ K++D G+ I W APE N + D W Sbjct 370 HGI-------CKVADFGLARVIDEEIYEAHTGAKFPIKWTAPEAAM--YNRFTIKSDVWS 420 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRP 857 FG L EI G P + E Q+ +R+P P +CP Q + C +P RP Sbjct 421 FGVVLYEIITYGRFPYPGMTNPEVLEKIQQNYRMPCPANCPKQFHDIMLDCWREDPASRP 480 Query 858 SFRTILRDLTRLQPHNLADVLTVNP 882 +F T+ L Sbjct 481 TFETLQWQLEEFFNSEGYRDPDAIH 505 Score = 289 bits (739), Expect = 5e-85, Method: Composition-based stats. Identities = 100/322 (31%), Positives = 147/322 (46%), Gaps = 27/322 (8%) Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923 T A++ K +K +R LG G FG+V ++ T Sbjct 207 CCKLLYPCLQAEKPQTAGLLRQANEEWEIEKTQIKLLRRLGAGQFGEVWEGLWNGT---- 262 Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 VAVK LK G + QE I++ L H +I+ C E+ + +V E + Sbjct 263 -TSVAVKTLKP--GTMSVEEFLQEASIMKRLRHPKLIQLYAVCTK--EEPIYIVTELMKY 317 Query 984 GSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 GSL +YL + + QL+ A Q+ GM+YL Q+YIHRDLAARN+L+ + K+ D Sbjct 318 GSLLEYLRGEDGVLKIEQLVDVAAQVASGMSYLEQQNYIHRDLAARNILVGEHGICKVAD 377 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLA+ + E E Y P+ W APE +F SDVWSFGV LYE++T+ Sbjct 378 FGLARVIDE--EIYEAHTGAKFPIKWTAPEAAMYNRFTIKSDVWSFGVVLYEIITYGR-- 433 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 MT + E +++ R+P P CP + + +M +CW + + RPT Sbjct 434 ------------FPYPGMTNPEVLEKIQQNYRMPCPANCPKQFHDIMLDCWREDPASRPT 481 Query 1162 FENLIPILKTVHEKYQGQAPSV 1183 FE L L+ + P Sbjct 482 FETLQWQLEEFFNSEGYRDPDA 503 >sp|P18652|KS6AA_CHICK Ribosomal protein S6 kinase 2 alpha OS=Gallus gallus OX=9031 GN=RPS6KA PE=2 SV=1 Length=752 Score = 326 bits (835), Expect = 1e-95, Method: Composition-based stats. Identities = 125/662 (19%), Positives = 215/662 (32%), Gaps = 122/662 (18%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + D + L LGQG+ V+ + D + L + Sbjct 73 EKADPSQFELLKVLGQGSFGKVFL----------VRKITPPDSNHLY-----------AM 111 Query 642 KVLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 KVL + + +++ V+H + +H + ++ +++ G L L Sbjct 112 KVLKKATLKVRDRVRTKIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRL 171 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 +E K +A +LA L +L + +++ ++ NILL G IKL+D Sbjct 172 SKEVMFTEEDVKFYLA-ELALGLDHLHSLGIIYRDLKPENILLDEEG-------HIKLTD 223 Query 760 PGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ A+ E++ + ++APE + +S S D W +G + E+ G P Sbjct 224 FGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS--ADWWSYGVLMFEML-TGSLPF 280 Query 816 QSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQR--------------PSFR 860 Q + E + +P+ + +L P R P + Sbjct 281 QGKDRKETMTLILKAKLGMPQFLSAEAQSLLRALFKRNPANRLGSGPDGAEEIKRHPFYS 340 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK-----------IRDLGEGHF- 908 TI + + V K + F Sbjct 341 TIDWNKLYRREIKPPFKPAVGQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFV 400 Query 909 ------------------GKVSLYCYDPTNDGTGEMV--AV-------------KALKAD 935 V G +V A+ K + Sbjct 401 ATGLMEDSKVKPAQPPLHSVVQQLHGKNIQFSDGYVVKEAIGVGSYSVCKRCIHKTTNME 460 Query 936 CGPQHRSGWKQ----EIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 + K+ EI+IL H +II K +D K + LV E + G L D + Sbjct 461 YAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDG--KYVYLVTELMRGGELLDKI 518 Query 991 PRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL-LDNDRL---VKIGDFGLA 1045 R + IC+ + YLH+Q +HRDL N+L +D ++I DFG A Sbjct 519 LRQKFFSEREASSVLHTICKTVEYLHSQGVVHRDLKPSNILYVDESGNPESIRICDFGFA 578 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 K + + + APE LK + D+WS GV LY +L C + P Sbjct 579 KQLRAENGLLMT---PCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGCTPFANGP 635 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + E I +T + + G D L+ + R T + + Sbjct 636 SDTPEEI------LTRIGGGKFSVNGGNW---DTISDVAKDLVSKMLHVDPHQRLTAKQV 686 Query 1166 IP 1167 + Sbjct 687 LQ 688 Score = 152 bits (383), Expect = 2e-36, Method: Composition-based stats. Identities = 50/286 (17%), Positives = 93/286 (33%), Gaps = 24/286 (8%) Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SHTH 669 +G E + + + +KV+D S D + E ++ + H + Sbjct 433 DGYVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSKRDPS----EEIEILLRYGQHPN 488 Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729 + + V G +VTE + G L + R++ V + + YL ++ Sbjct 489 IITLKDVYDDGKYVYLVTELMRGGELLDKILRQKF-FSEREASSVLHTICKTVEYLHSQG 547 Query 730 LVHGNVCGRNIL-LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL----APECL 784 +VH ++ NIL + G E I++ D G + + + APE L Sbjct 548 VVHRDLKPSNILYVDESGNPES----IRICDFGFAKQLRAENGLLMTPCYTANFVAPEVL 603 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-------HRLPEPS 837 D W G L + S + +E + + Sbjct 604 K--RQGYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTI 661 Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 L S+ L +P QR + + +L+ Q +L D Sbjct 662 SDVAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLPQSQLNYQD 707 >sp|Q9UK32|KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 OS=Homo sapiens OX=9606 GN=RPS6KA6 PE=1 SV=1 Length=745 Score = 325 bits (834), Expect = 1e-95, Method: Composition-based stats. Identities = 129/696 (19%), Positives = 230/696 (33%), Gaps = 138/696 (20%) Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 + P T ++ + + + D + L LGQG+ V+ R + Sbjct 53 KEIPITHHVKE-GYEKADPAQFELLKVLGQGSFGKVFLVRKKT----------------- 94 Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIM 685 G D GQ +KVL + + ++ +V+H + +H + + Sbjct 95 --GPDAGQ--LYAMKVLKKASLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYL 150 Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 + +++ G + L +E K +A +LA AL +L +V+ ++ NILL + Sbjct 151 ILDFLRGGDVFTRLSKEVLFTEEDVKFYLA-ELALALDHLHQLGIVYRDLKPENILLDEI 209 Query 746 GLAEGTSPFIKLSDPGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFG 801 G IKL+D G+ ++ +E++ + ++APE + S + D W +G Sbjct 210 G-------HIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVV--NRRGHSQSADWWSYG 260 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQRPSFR 860 + E+ G P Q + +E + + +P+ + +L P R Sbjct 261 VLMFEML-TGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPANRLGSE 319 Query 861 TILRDLTRLQ---------PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG----- 906 + L D F + K G Sbjct 320 GVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPEFTAKTPKDSPGLPASA 379 Query 907 -----------------------------------------HFGKVSL-----------Y 914 FG+V Sbjct 380 NAHQLFKGFSFVATSIAEEYKITPITSANVLPIVQINGNAAQFGEVYELKEDIGVGSYSV 439 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKS 973 C + T AVK + + +EI+IL H +II K +D + Sbjct 440 CKRCIHATTNMEFAVKIIDKS-----KRDPSEEIEILMRYGQHPNIITLKDVFDDG--RY 492 Query 974 LQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032 + LV + + G L D L + + I + + YLH Q +HRDL N+L Sbjct 493 VYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDLKPSNILYM 552 Query 1033 ND----RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 ++ ++I DFG AK + + + APE L + + A D+WS G Sbjct 553 DESASADSIRICDFGFAKQLRGENGLLLT---PCYTANFVAPEVLMQQGYDAACDIWSLG 609 Query 1089 VTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 V Y +L + P E L+ I G+ ++ D Sbjct 610 VLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNW-----------DNISDGAKD 658 Query 1147 LMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182 L+ + + R T E + LK ++ Q P+ Sbjct 659 LLSHMLHMDPHQRYTAEQI---LKHSWITHRDQLPN 691 Score = 150 bits (379), Expect = 6e-36, Method: Composition-based stats. Identities = 49/316 (16%), Positives = 92/316 (29%), Gaps = 33/316 (10%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETA 659 VYE E+ + + +K++D S D + E Sbjct 422 FGEVYE---------LKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPS----EEI 468 Query 660 SLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQL 718 ++ + H ++ + V G +VT+ ++ G L + +++ + + Sbjct 469 EILMRYGQHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKC-FSEREASDILYVI 527 Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPW 778 + + YL + +VH ++ NIL ++ I++ D G + + Sbjct 528 SKTVDYLHCQGVVHRDLKPSNIL---YMDESASADSIRICDFGFAKQLRGENGLLLTPCY 584 Query 779 L----APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS--EKEHFYQRQHR 832 APE L A D W G L G P + E+ + Sbjct 585 TANFVAPEVLMQ--QGYDAACDIWSLGV-LFYTMLAGYTPFANGPNDTPEEILLRIGNGK 641 Query 833 L------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 + L S L +P QR + IL+ L + D Sbjct 642 FSLSGGNWDNISDGAKDLLSHMLHMDPHQRYTAEQILKHSWITHRDQLPNDQPKRNDVSH 701 Query 887 SDPTVFHKRYLKKIRD 902 Y Sbjct 702 VVKGAMVATYSALTHK 717 >sp|Q62662|FRK_RAT Tyrosine-protein kinase FRK OS=Rattus norvegicus OX=10116 GN=Frk PE=1 SV=3 Length=506 Score = 318 bits (814), Expect = 1e-95, Method: Composition-based stats. Identities = 101/459 (22%), Positives = 174/459 (38%), Gaps = 74/459 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VA R + + G + + +L + G +LI S S L+V Sbjct 106 VAEDRSLQA-EPWFFGAIKRADAEKQLLYSENQTGAFLIRESESQKGDFSLSVLDEG--- 161 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 ++ + I + D ++F ++ E + C L + CL Sbjct 162 ------VVKHYRIRRLDEGGFFLTRRKTFSTLNEFVNYYTTT---SDGLCVKLEKPCL-- 210 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + +P L+ + +D+ I L LG G V+EG Sbjct 211 ----------KIQVPTPFDLSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGLW------ 254 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 V +K L P D F A +M + H L ++ Sbjct 255 -------------------NNTTPVAVKTLKPGSMDPN-DFLREAQIMKSLRHPKLIQLY 294 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHG 733 VC ++TE + HG L +L+ + G + + ++ +A Q+AS ++YLE++N +H Sbjct 295 AVCTLEDPIYIITELMRHGSLQEYLQNDGGSKIRLTQQVDMAAQVASGMAYLESQNYIHR 354 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLG--------ALSREERVERIPWLAPECLP 785 ++ RN+L+ + K++D G+ S+ E + W APE + Sbjct 355 DLAARNVLVGEHNIY-------KVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIR 407 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLAT 843 N S D W FG L EI G+ P + ++ H + +RLP+P +CP Q + Sbjct 408 T--NKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIHMLGQNYRLPQPSNCPEQFYS 465 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 + +C EP QRP+F T+ L + + T N Sbjct 466 IMMECWNVEPKQRPTFETLHWKLEDYFEPDSSYSDTNNF 504 Score = 281 bits (720), Expect = 2e-82, Method: Composition-based stats. Identities = 99/309 (32%), Positives = 150/309 (49%), Gaps = 27/309 (9%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 + + D + ++ ++ LG G FG+V ++ T VAV Sbjct 208 PCLKIQVPTPFDLSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNT-----TPVAV 262 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K LK G + + +E I+++L H +I+ C E + ++ E + GSL++Y Sbjct 263 KTLKP--GSMDPNDFLREAQIMKSLRHPKLIQLYAVCT--LEDPIYIITELMRHGSLQEY 318 Query 990 LPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 L I L Q + A Q+ GMAYL +Q+YIHRDLAARNVL+ + K+ DFGLA+ Sbjct 319 LQNDGGSKIRLTQQVDMAAQVASGMAYLESQNYIHRDLAARNVLVGEHNIYKVADFGLAR 378 Query 1047 AVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + Y + + PV W APE ++ KF SDVWSFG+ LYE++T+ Sbjct 379 VFKVDNEDIYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGK------ 432 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + MT ++ +L + RLP+P CP + Y +M CW E RPTFE L Sbjct 433 --------MPYSGMTGAQVIHMLGQNYRLPQPSNCPEQFYSIMMECWNVEPKQRPTFETL 484 Query 1166 IPILKTVHE 1174 L+ E Sbjct 485 HWKLEDYFE 493 >sp|O45539|SRC2_CAEEL Tyrosine protein-kinase src-2 OS=Caenorhabditis elegans OX=6239 GN=src-2 PE=1 SV=2 Length=507 Score = 318 bits (814), Expect = 1e-95, Method: Composition-based stats. Identities = 101/437 (23%), Positives = 164/437 (38%), Gaps = 73/437 (17%) Query 446 SIRDGIHGP---LLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502 + G + E G +L+ S S + L L+V + D ++ R+ Sbjct 120 ESQPWYFGKMRRIDAEKCLLHTLNEHGAFLVRDSESRQHDLSLSVREN----DSVKHYRI 175 Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562 R+ D R F ++ +L A Q A C +L C Sbjct 176 RQL-----DHGGYFIARRRPFATLHDLIAHYQRE---ADGLCVNLGAPC----------- 216 Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 +P+T + VD++ + + +G G V+EGR V Sbjct 217 ---AKSEAPQTTTFTYDDQWEVDRRSVRLIRQIGAGQFGEVWEGRWNVN----------- 262 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 + V +K L D F A +M ++ H L ++ VC R Sbjct 263 --------------VPVAVKKLKAGTADP-TDFLAEAQIMKKLRHPKLLSLYAVCTRDEP 307 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 ++VTE ++ L +L+R M + ++ Q+A+ ++YLE N +H ++ RNIL+ Sbjct 308 ILIVTELMQ-ENLLTFLQRRGRQCQMPQLVEISAQVAAGMAYLEEMNFIHRDLAARNILI 366 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMD 796 S +K++D G+ + E R I W APE N +T D Sbjct 367 NN-------SLSVKIADFGLARILMKENEYEARTGARFPIKWTAPEAA--NYNRFTTKSD 417 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPT 854 W FG L EI G P + +E +R+P P CP L + QC +P Sbjct 418 VWSFGILLTEIVTFGRLPYPGMTNAEVLQQVDAGYRMPCPAGCPVTLYDIMQQCWRSDPD 477 Query 855 QRPSFRTILRDLTRLQP 871 +RP+F T+ L L Sbjct 478 KRPTFETLQWKLEDLFN 494 Score = 273 bits (698), Expect = 3e-79, Method: Composition-based stats. Identities = 94/321 (29%), Positives = 145/321 (45%), Gaps = 27/321 (8%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915 R L D +R ++ IR +G G FG+V Sbjct 199 AHYQREADGLCVNLGAPCAKSEAPQTTTFTYDDQWEVDRRSVRLIRQIGAGQFGEVWEGR 258 Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 ++ VAVK LKA G + + E I++ L H ++ C ++ + Sbjct 259 WNV-----NVPVAVKKLKA--GTADPTDFLAEAQIMKKLRHPKLLSLYAVCTR--DEPIL 309 Query 976 LVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033 +V E + +L +L R + QL+ + Q+ GMAYL ++IHRDLAARN+L++N Sbjct 310 IVTELMQE-NLLTFLQRRGRQCQMPQLVEISAQVAAGMAYLEEMNFIHRDLAARNILINN 368 Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 VKI DFGLA+ + + +E Y R P+ W APE +F SDVWSFG+ L E Sbjct 369 SLSVKIADFGLARILMKENE-YEARTGARFPIKWTAPEAANYNRFTTKSDVWSFGILLTE 427 Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 ++T + MT + + ++ G R+P P CP +Y +M+ CW Sbjct 428 IVTFGR--------------LPYPGMTNAEVLQQVDAGYRMPCPAGCPVTLYDIMQQCWR 473 Query 1154 TEASFRPTFENLIPILKTVHE 1174 ++ RPTFE L L+ + Sbjct 474 SDPDKRPTFETLQWKLEDLFN 494 >sp|P00528|SRC64_DROME Tyrosine-protein kinase Src64B OS=Drosophila melanogaster OX=7227 GN=Src64B PE=1 SV=3 Length=552 Score = 319 bits (818), Expect = 1e-95, Method: Composition-based stats. Identities = 97/435 (22%), Positives = 159/435 (37%), Gaps = 70/435 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502 + D +L L E+ G +L+ S +P L+V + + Sbjct 158 NSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDG----RGYHV 213 Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL-PQPGETSNL 561 + + I+ D ++FPS++ L A L C L R C PQP Sbjct 214 KHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNAL---GLCHILSRPCPKPQPQMWDLG 270 Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 +R + + + EI L LG+G V+ G+ R Sbjct 271 PELR--------------DKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNS---------- 306 Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 + V +K L A AF + A++M + H L ++ VC + Sbjct 307 ---------------IDVAVKTLREGTMSTA-AFLQEAAIMKKFRHNRLVALYAVCSQEE 350 Query 682 ENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNI 740 +V EY+ G L +LR G + + +A Q+AS + YLE+K L+H ++ RN+ Sbjct 351 PIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNV 410 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAM 795 L+ +A K+ D G+ E + + W APE + G S Sbjct 411 LIGENNVA-------KICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYG--KFSIKS 461 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP----EPSCPQLATLTSQCLTY 851 D W +G L+E+ G+ P E +R R+P + L QC Sbjct 462 DVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDA 521 Query 852 EPTQRPSFRTILRDL 866 P +RP+F + Sbjct 522 VPEKRPTFEFLNHYF 536 Score = 259 bits (663), Expect = 4e-74, Method: Composition-based stats. Identities = 93/319 (29%), Positives = 143/319 (45%), Gaps = 30/319 (9%) Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918 + +P + D + ++ +R LG G+FG+V + Sbjct 246 KNALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRN 305 Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978 + D VAVK L+ G + + QE I++ H ++ C E+ + +V Sbjct 306 SID-----VAVKTLRE--GTMSTAAFLQEAAIMKKFRHNRLVALYAVCSQ--EEPIYIVQ 356 Query 979 EYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035 EY+ GSL D+L + L+ A Q+ GM YL ++ IHRDLAARNVL+ + Sbjct 357 EYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENN 416 Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 + KI DFGLA+ + + Y ++ PV W APE + KF SDVWS+G+ L EL Sbjct 417 VAKICDFGLARVIADDE--YCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELF 474 Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK--CPCEVYHLMKNCWE 1153 T+ + M + E +ERG R+P+P P +Y L+ CW+ Sbjct 475 TYGQ--------------VPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWD 520 Query 1154 TEASFRPTFENLIPILKTV 1172 RPTFE L ++ Sbjct 521 AVPEKRPTFEFLNHYFESF 539 >sp|Q552C6|ZAK2_DICDI Dual specificity protein kinase zak2 OS=Dictyostelium discoideum OX=44689 GN=zak2 PE=1 SV=1 Length=635 Score = 320 bits (820), Expect = 8e-95, Method: Composition-based stats. Identities = 104/600 (17%), Positives = 203/600 (34%), Gaps = 119/600 (20%) Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K+++ ++ ++ ++ + + EY+E Sbjct 42 VAVKIINKKFFK-----RNETDILEKIRLFNIPRYYSHAEDDNYIYIYMEYIE------- 89 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 +++ + + + L LS+L ++H ++ NI+L + G+ +KL Sbjct 90 -DKKQLRFKESEIISMIADLTETLSFLHKHQILHRDIKPSNIILDKNGV-------LKLI 141 Query 759 DPGVGLGALSREE-----------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 D G + +++ ++APE + + D W G T+LEI Sbjct 142 DFGSSIIDQQQDDGDNICKESSFAITGTHTYMAPEV--KKLHRSTKKSDVWSLGCTVLEI 199 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 G P + + +P + +CL +P +R +L Sbjct 200 V--GGNP---------KKIFDGIPIIPNHVSEIMVDFIKRCLIIDPNKRSHMEELLTHRL 248 Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG---------------------EG 906 N + ++ + K + +G Sbjct 249 ISSMVGQNKNRENNIEPKFNNDYLSSKFPERFAPRFEKPKWEIEFNELKFNKDDTVGGDG 308 Query 907 HFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHIIKYKG 964 F V Y+ T VA+K +K G + E+ I+ L H +I+++ Sbjct 309 FFSVVKKGYYNET------EVAIKLIKKAHGENVTVCDTFYHEVLIISNLRHPNIVQFIA 362 Query 965 CCE--DQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQH 1018 C D E + +V E++ G+L ++ I + I +GM Y H Q Sbjct 363 ACIKFDNKEVNHCIVSEWMSGGNLSQFISNERKILEINPHLRVKILLDIAKGMLYSHRQG 422 Query 1019 YIHRDLAARNVLLD---------------------NDRLVKIGDFGLAKAVPEGHEYYRV 1057 IHRDL + NVLL+ ++ + K+ DFGL+ E + Sbjct 423 IIHRDLTSNNVLLNFRKKKLLNNNSSNNDEQFYDSDEIIAKVCDFGLSSNQSESKKL--- 479 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 + + APE L SD++SFG+ ++++ ++ Sbjct 480 ---RGGSIHYMAPENLNGSPINEKSDIYSFGLLVWQMFSYASP------------NTIYS 524 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP-TFENLIPILKTVHEKY 1176 + + + R P P + L+ CW+ RP F +I LK +++ Y Sbjct 525 PKEMASMVSDEKLNYRPQIPFNVPLKFKELITQCWDRNPLNRPKDFSEIIDKLKDINQIY 584 Score = 190 bits (483), Expect = 2e-49, Method: Composition-based stats. Identities = 51/310 (16%), Positives = 109/310 (35%), Gaps = 61/310 (20%) Query 582 HRVDQKEITQLS---HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 ++ E+ G G + V +G E Sbjct 289 WEIEFNELKFNKDDTVGGDGFFSVVKKG--------------------------YYNETE 322 Query 639 VVLKVLDPSHHDIA---LAFYETASLMSQVSHTHLAFVHGVCVRGPE----NIMVTEYVE 691 V +K++ +H + FY ++S + H ++ C++ + +V+E++ Sbjct 323 VAIKLIKKAHGENVTVCDTFYHEVLIISNLRHPNIVQFIAACIKFDNKEVNHCIVSEWMS 382 Query 692 HGPLDVWLRRERGHVPMA--WKMVVAQQLASALSYLENKNLVHGNVCGRNILLA------ 743 G L ++ ER + + ++ + +A + Y + ++H ++ N+LL Sbjct 383 GGNLSQFISNERKILEINPHLRVKILLDIAKGMLYSHRQGIIHRDLTSNNVLLNFRKKKL 442 Query 744 --------RLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIPWLAPECLPGGANSLSTA 794 + K+ D G+ + S++ R I ++APE L G + ++ Sbjct 443 LNNNSSNNDEQFYDSDEIIAKVCDFGLSSNQSESKKLRGGSIHYMAPENLNG--SPINEK 500 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-----QRQHRLPEPSCPQLATLTSQCL 849 D + FG + ++ +P SP E + ++P + L +QC Sbjct 501 SDIYSFGLLVWQMFSYA-SPNTIYSPKEMASMVSDEKLNYRPQIPFNVPLKFKELITQCW 559 Query 850 TYEPTQRPSF 859 P RP Sbjct 560 DRNPLNRPKD 569 Score = 155 bits (391), Expect = 8e-38, Method: Composition-based stats. Identities = 48/246 (20%), Positives = 95/246 (39%), Gaps = 45/246 (18%) Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 +VAVK + + E DIL + +I +Y + + + + MEY+ Sbjct 41 IVAVKIINKKFFK------RNETDILEKIRLFNIPRYY--SHAEDDNYIYIYMEYIEDK- 91 Query 986 LRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 + ++++ + E +++LH +HRD+ N++LD + ++K+ DFG + Sbjct 92 -----KQLRFKESEIISMIADLTETLSFLHKHQILHRDIKPSNIILDKNGVLKLIDFGSS 146 Query 1046 KAVPEGHEYYRVREDG----DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 + + + ++ + APE K ++ SDVWS G T+ E++ Sbjct 147 IIDQQQDDGDNICKESSFAITGTHTYMAPEVKKLHRSTKKSDVWSLGCTVLEIVGGN--- 203 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 P K + I I P+ + +K C + + R Sbjct 204 ---PKKIFDGIPI---------------------IPNHVSEIMVDFIKRCLIIDPNKRSH 239 Query 1162 FENLIP 1167 E L+ Sbjct 240 MEELLT 245 >sp|P42685|FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo sapiens OX=9606 GN=FRK PE=1 SV=1 Length=505 Score = 314 bits (805), Expect = 2e-94, Method: Composition-based stats. Identities = 98/441 (22%), Positives = 169/441 (38%), Gaps = 74/441 (17%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VA R + + G + + +L + G +LI S S L+V Sbjct 105 VAEDRSLQA-EPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLD----- 158 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 ++ + I++ D R F ++ E + + C L + CL Sbjct 159 ----GAVVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHYTKT---SDGLCVKLGKPCL-- 209 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + +P L+ + +D+ I L LG G V+EG Sbjct 210 ----------KIQVPAPFDLSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGLW------ 253 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 V +K L P D F A +M + H L ++ Sbjct 254 -------------------NNTTPVAVKTLKPGSMDPN-DFLREAQIMKNLRHPKLIQLY 293 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHG 733 VC ++TE + HG L +L+ + G + + ++ +A Q+AS ++YLE++N +H Sbjct 294 AVCTLEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHR 353 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLG--------ALSREERVERIPWLAPECLP 785 ++ RN+L+ + K++D G+ SR E + W APE + Sbjct 354 DLAARNVLVGEHNIY-------KVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIR 406 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLAT 843 +N S D W FG L EI G+ P + ++ + +RLP+P +CP Q Sbjct 407 --SNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYN 464 Query 844 LTSQCLTYEPTQRPSFRTILR 864 + +C EP +RP+F T+ Sbjct 465 IMLECWNAEPKERPTFETLRW 485 Score = 282 bits (721), Expect = 2e-82, Method: Composition-based stats. Identities = 99/309 (32%), Positives = 151/309 (49%), Gaps = 27/309 (9%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 + + D + ++ ++ LG G FG+V ++ T VAV Sbjct 207 PCLKIQVPAPFDLSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNT-----TPVAV 261 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K LK G + + +E I++ L H +I+ C E + ++ E + GSL++Y Sbjct 262 KTLKP--GSMDPNDFLREAQIMKNLRHPKLIQLYAVCT--LEDPIYIITELMRHGSLQEY 317 Query 990 LPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 L I L Q + A Q+ GMAYL +++YIHRDLAARNVL+ + K+ DFGLA+ Sbjct 318 LQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLAR 377 Query 1047 AVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + Y R + PV W APE ++ KF SDVWSFG+ LYE++T+ Sbjct 378 VFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGK------ 431 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + MT ++ ++L + RLP+P CP + Y++M CW E RPTFE L Sbjct 432 --------MPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERPTFETL 483 Query 1166 IPILKTVHE 1174 L+ E Sbjct 484 RWKLEDYFE 492 >sp|Q922K9|FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus musculus OX=10090 GN=Frk PE=1 SV=3 Length=512 Score = 315 bits (806), Expect = 3e-94, Method: Composition-based stats. Identities = 100/459 (22%), Positives = 171/459 (37%), Gaps = 74/459 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VA R + + G + + +L + G +LI S S L+V Sbjct 112 VAEDRSLQA-EPWFFGAIKRADAEKQLLYSENQTGAFLIRESESQKGDFSLSVLDEG--- 167 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 ++ + I + D + F ++ E + C L + CL Sbjct 168 ------VVKHYRIRRLDEGGFFLTRRKVFSTLNEFVNYYTTT---SDGLCVKLEKPCL-- 216 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + +P L+ +D+ I L LG G V+EG Sbjct 217 ----------KIQVPTPFDLSYKTADQWEIDRNSIQLLKRLGSGQFGEVWEGLW------ 260 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 V +K L P D F A +M + H L ++ Sbjct 261 -------------------NNTTPVAVKTLKPGSMDPN-DFLREAQIMKSLRHPKLIQLY 300 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHG 733 VC ++TE + HG L +L+ + G + + ++ +A Q+AS ++YLE++N +H Sbjct 301 AVCTLEDPIYIITELMRHGSLQEYLQNDGGSKIHLIQQVDMAAQVASGMAYLESQNYIHR 360 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLG--------ALSREERVERIPWLAPECLP 785 ++ RN+L+ + K++D G+ S+ E + W APE + Sbjct 361 DLAARNVLVGEHNIY-------KVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIR 413 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLAT 843 N S D W FG L EI G+ P + ++ + +RLP+P +CP Q + Sbjct 414 T--NKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLSQNYRLPQPSNCPQQFYS 471 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 + +C EP QRP+F T+ L + + T N Sbjct 472 IMLECWNVEPKQRPTFETLHWKLEDYFETDCSYSDTNNF 510 Score = 282 bits (722), Expect = 1e-82, Method: Composition-based stats. Identities = 99/309 (32%), Positives = 152/309 (49%), Gaps = 27/309 (9%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 + + +D + ++ ++ LG G FG+V ++ T VAV Sbjct 214 PCLKIQVPTPFDLSYKTADQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNT-----TPVAV 268 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K LK G + + +E I+++L H +I+ C E + ++ E + GSL++Y Sbjct 269 KTLKP--GSMDPNDFLREAQIMKSLRHPKLIQLYAVCT--LEDPIYIITELMRHGSLQEY 324 Query 990 LPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 L I L Q + A Q+ GMAYL +Q+YIHRDLAARNVL+ + K+ DFGLA+ Sbjct 325 LQNDGGSKIHLIQQVDMAAQVASGMAYLESQNYIHRDLAARNVLVGEHNIYKVADFGLAR 384 Query 1047 AVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + Y + + PV W APE ++ KF SDVWSFG+ LYE++T+ Sbjct 385 VFKVDNEDIYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGK------ 438 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + MT ++ ++L + RLP+P CP + Y +M CW E RPTFE L Sbjct 439 --------MPYSGMTGAQVIQMLSQNYRLPQPSNCPQQFYSIMLECWNVEPKQRPTFETL 490 Query 1166 IPILKTVHE 1174 L+ E Sbjct 491 HWKLEDYFE 499 >sp|P27446|FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiphophorus hellerii OX=8084 GN=fyn PE=2 SV=3 Length=537 Score = 312 bits (800), Expect = 3e-93, Method: Composition-based stats. Identities = 95/465 (20%), Positives = 158/465 (34%), Gaps = 67/465 (14%) Query 426 LTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYR 482 LT S Y+ P + D G L + +L G YLI S + Sbjct 125 LTTGGSGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSTGNPRGTYLIRESETTKGA 184 Query 483 LILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGD 542 L++ D + ++ + I + D F ++++L RA Sbjct 185 FSLSIRDW----DDEKGDHVKHYKIRKLDSGGYYITTRAQFDTLQQLVQHYSD---RAAG 237 Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTN 602 C L C L++ + ++ + + LG G Sbjct 238 LCCRLVVPCHK-------------GMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGE 284 Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662 V+ G +V +K L P +F E A +M Sbjct 285 VWMGTWNGT-------------------------TKVAVKTLKPGTMSP-ESFLEEAQIM 318 Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASA 721 ++ H L ++ V +VTEY+ G L +L+ G + + + +A Q+A+ Sbjct 319 KKLRHDKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377 Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RI 776 ++Y+E N +H ++ NIL+ G + K++D G+ E I Sbjct 378 MAYIERMNYIHRDLRSANILV-------GDNLVCKIADFGLARLIEDNEYTARQGAKFPI 430 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836 W APE G + D W FG L E+ G P + E +R +R+P P Sbjct 431 KWTAPEAALYG--RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 488 Query 837 S-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 CP L L QC +P +RP+F + L Sbjct 489 QDCPASLHELMLQCWKKDPEERPTFEYLQAFLEDYFTATEPQYQP 533 Score = 296 bits (758), Expect = 3e-87, Method: Composition-based stats. Identities = 95/318 (30%), Positives = 148/318 (47%), Gaps = 29/318 (9%) Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 + P + + D + L+ I+ LG G FG+V + ++ T Sbjct 239 CCRLVVPCHKGMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGT----- 293 Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 VAVK LK G + +E I++ L H+ +++ E+ + +V EY+ G Sbjct 294 TKVAVKTLKP--GTMSPESFLEEAQIMKKLRHDKLVQLYAVV---SEEPIYIVTEYMSKG 348 Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ ++ + KI D Sbjct 349 SLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGDNLVCKIAD 408 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + M + E +ERG R+P P CP ++ LM CW+ + RPT Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPASLHELMLQCWKKDPEERPT 512 Query 1162 FENLIPILKTVHEKYQGQ 1179 FE L L+ + Q Sbjct 513 FEYLQAFLEDYFTATEPQ 530 >sp|Q9V9J3|SRC42_DROME Tyrosine-protein kinase Src42A OS=Drosophila melanogaster OX=7227 GN=Src42A PE=1 SV=1 Length=517 Score = 311 bits (796), Expect = 8e-93, Method: Composition-based stats. Identities = 93/451 (21%), Positives = 165/451 (37%), Gaps = 72/451 (16%) Query 446 SIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502 + + KL E G +LI S S L+V D ++ R+ Sbjct 126 EAEPWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRD----GDTVKHYRI 181 Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562 R+ D +F +++EL + C +L + C+ + + Sbjct 182 RQL-----DEGGFFIARRTTFRTLQELVEHYSKD---SDGLCVNLCKPCVQIEKPVTEGL 233 Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 R +D+ + + LG G +V+EG Sbjct 234 SHRTR------------DQWEIDRTSLKFVRKLGSGQFGDVWEGLW-------------- 267 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 V +K L D F A +M ++ HT L ++ VC Sbjct 268 -----------NNTTPVAIKTLKSGTMDP-KDFLAEAQIMKKLRHTKLIQLYAVCTVEEP 315 Query 683 NIMVTEYVEHGPLDVWLR---RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRN 739 ++TE ++HG L +L+ + + M + +A Q+A+ ++YLE++N +H ++ RN Sbjct 316 IYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARN 375 Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREE--RVE---RIPWLAPECLPGGANSLSTA 794 +L+ G +K++D G+ E RV I W APE + S Sbjct 376 VLV-------GDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAA--NYSKFSIK 426 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC--PQLATLTSQCLTYE 852 D W FG L E+ G P + +E + +R+P+P P+L + +C + Sbjct 427 SDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKD 486 Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 P +RP+F T+ L + +D Sbjct 487 PMRRPTFETLQWKLEDFYTSDQSDYKEAQAY 517 Score = 276 bits (707), Expect = 2e-80, Method: Composition-based stats. Identities = 104/321 (32%), Positives = 145/321 (45%), Gaps = 30/321 (9%) Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923 + +T D + LK +R LG G FG V ++ T Sbjct 215 CVNLCKPCVQIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNT---- 270 Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 VA+K LK G + E I++ L H +I+ C E+ + ++ E + Sbjct 271 -TPVAIKTLK--SGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTV--EEPIYIITELMKH 325 Query 984 GSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 GSL +YL S+ + L+ A QI GMAYL +Q+YIHRDLAARNVL+ + +VK Sbjct 326 GSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVK 385 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 I DFGLA+ + E Y R P+ W APE KF SDVWSFG+ L EL+T+ Sbjct 386 IADFGLARLIKEDE--YEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYG 443 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 I MT + +E G R+P+P C +Y +M CW + Sbjct 444 R--------------IPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMR 489 Query 1159 RPTFENLIPILKTVHEKYQGQ 1179 RPTFE L L+ + Q Sbjct 490 RPTFETLQWKLEDFYTSDQSD 510 >sp|Q02977|YRK_CHICK Proto-oncogene tyrosine-protein kinase Yrk OS=Gallus gallus OX=9031 GN=YRK PE=2 SV=2 Length=536 Score = 311 bits (797), Expect = 8e-93, Method: Composition-based stats. Identities = 89/457 (19%), Positives = 156/457 (34%), Gaps = 68/457 (15%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + +L G +LI S + L++ Sbjct 137 VAPVDSIQA-EEWYFGKIGRKDAERQLLCHGNCRGTFLIRESETTKGAYSLSIRDW---- 191 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + ++ + I + D F ++++L + RA C L C Sbjct 192 DEAKGDHVKHYKIRKLDSGGYYITTRAQFDTIQQLVQHY---IERAAGLCCRLAVPCPK- 247 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 L++ + ++ + L LG G V+ G Sbjct 248 ------------GTPKLADLSVKTKDVWEIPRESLQLLQKLGNGQFGEVWMGTWNGT--- 292 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P AF E A +M ++ H L ++ Sbjct 293 ----------------------TKVAVKTLKPGTMSP-EAFLEEAQIMKRLRHDKLVQLY 329 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTE++ G L +L+ G + + + +A Q+A+ ++Y+E N +H Sbjct 330 AVVSE-EPIYIVTEFMSQGSLLDFLKDGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHR 388 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 389 DLRAANILV-------GDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALFG- 440 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846 + D W FG L E+ G P + E +R +R+ P P L + Sbjct 441 -KFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMQCPGGCPPSLHDVMV 499 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 QC EP +RP+F + L + Sbjct 500 QCWKREPEERPTFEYLQSFLEDYFTATEPQYQPGDNQ 536 Score = 286 bits (732), Expect = 1e-83, Method: Composition-based stats. Identities = 96/318 (30%), Positives = 145/318 (46%), Gaps = 29/318 (9%) Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 P + D + L+ ++ LG G FG+V + ++ T Sbjct 238 CCRLAVPCPKGTPKLADLSVKTKDVWEIPRESLQLLQKLGNGQFGEVWMGTWNGT----- 292 Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 VAVK LK G + +E I++ L H+ +++ E+ + +V E++ G Sbjct 293 TKVAVKTLKP--GTMSPEAFLEEAQIMKRLRHDKLVQLYAVV---SEEPIYIVTEFMSQG 347 Query 985 SLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 SL D+L + L QL+ A QI GMAY+ +YIHRDL A N+L+ ++ + KI D Sbjct 348 SLLDFLKDGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLVCKIAD 407 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLA+ + + Y R+ P+ W APE KF SDVWSFG+ L EL+T Sbjct 408 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALFGKFTIKSDVWSFGILLTELVTKGR-- 463 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + M + E +ERG R+ P CP ++ +M CW+ E RPT Sbjct 464 ------------VPYPGMNNREVLEQVERGYRMQCPGGCPPSLHDVMVQCWKREPEERPT 511 Query 1162 FENLIPILKTVHEKYQGQ 1179 FE L L+ + Q Sbjct 512 FEYLQSFLEDYFTATEPQ 529 >sp|Q6EWH2|FYNA_DANRE Tyrosine-protein kinase fyna OS=Danio rerio OX=7955 GN=fyna PE=1 SV=2 Length=537 Score = 310 bits (795), Expect = 2e-92, Method: Composition-based stats. Identities = 94/465 (20%), Positives = 158/465 (34%), Gaps = 67/465 (14%) Query 426 LTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYR 482 LT + Y+ P + D G L + +L G +LI S + Sbjct 125 LTTGGTGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSNGNPRGTFLIRESETTKGA 184 Query 483 LILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGD 542 L++ D + ++ + I + D F ++++L RA Sbjct 185 YSLSIQDW----DETKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVHHYSA---RAAG 237 Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTN 602 C L C L++ + ++ + + LG G Sbjct 238 LCCRLIVPCHK-------------GMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGE 284 Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662 V+ G +V +K L P +F E A +M Sbjct 285 VWMGTWNGN-------------------------TKVAVKTLKPGTMSP-ESFLEEAQIM 318 Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASA 721 ++ H L ++ V +VTEY+ G L +L+ G + + + +A Q+A+ Sbjct 319 KKLRHDKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKDGEGRGLKLPNLVDMAAQVAAG 377 Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RI 776 ++Y+E N +H ++ NIL+ G S K++D G+ E I Sbjct 378 MAYIERMNYIHRDLRSANILV-------GDSLVCKIADFGLARLIEDNEYTARQGAKFPI 430 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836 W APE G + D W FG L E+ G P + E +R +R+P P Sbjct 431 KWTAPEAALYG--RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 488 Query 837 S-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 CP L L QC +P +RP+F + L Sbjct 489 QDCPSSLHELMLQCWKRDPEERPTFEYLQAFLEDYFTATEPQYQP 533 Score = 294 bits (753), Expect = 1e-86, Method: Composition-based stats. Identities = 94/318 (30%), Positives = 145/318 (46%), Gaps = 29/318 (9%) Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 + P + + D + L+ I+ LG G FG+V + ++ Sbjct 239 CCRLIVPCHKGMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 293 Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 VAVK LK G + +E I++ L H+ +++ E+ + +V EY+ G Sbjct 294 TKVAVKTLKP--GTMSPESFLEEAQIMKKLRHDKLVQLYAVV---SEEPIYIVTEYMSKG 348 Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 SL D+L + L L+ A Q+ GMAY+ +YIHRDL + N+L+ + + KI D Sbjct 349 SLLDFLKDGEGRGLKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGDSLVCKIAD 408 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + M + E +ERG R+P P CP ++ LM CW+ + RPT Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPSSLHELMLQCWKRDPEERPT 512 Query 1162 FENLIPILKTVHEKYQGQ 1179 FE L L+ + Q Sbjct 513 FEYLQAFLEDYFTATEPQ 530 >sp|P13406|FYN_XENLA Tyrosine-protein kinase Fyn OS=Xenopus laevis OX=8355 GN=fyn PE=2 SV=3 Length=537 Score = 310 bits (794), Expect = 2e-92, Method: Composition-based stats. Identities = 93/465 (20%), Positives = 156/465 (34%), Gaps = 67/465 (14%) Query 426 LTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYR 482 LT + Y+ P + + G L + +L G YLI S + Sbjct 125 LTTGGTGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTYLIRESETTKGA 184 Query 483 LILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGD 542 L++ D M+ ++ + I + D F ++++L RA Sbjct 185 YSLSIRDW----DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSE---RAAG 237 Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTN 602 C L C L++ + ++ + + LG G Sbjct 238 LCCRLVVPCHK-------------GMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGE 284 Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662 V+ G +V +K L P +F E A +M Sbjct 285 VWMGTWNGN-------------------------TKVAIKTLKPGTMSP-ESFLEEAQIM 318 Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASA 721 ++ H L ++ V +VTEY+ G L +L+ G + + + +A Q+A Sbjct 319 KKLKHDKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVARG 377 Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RI 776 ++Y+E N +H ++ NIL+ G K++D G+ E I Sbjct 378 MAYIERMNYIHRDLRSANILV-------GNGLICKIADFGLARLIEDNEYTARQGAKFPI 430 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836 W APE G + D W FG L E+ G P + E +R +R+P P Sbjct 431 KWTAPEAALYG--RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCP 488 Query 837 S-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 CP L L C +P +RP+F + L Sbjct 489 QDCPISLHELMLNCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 533 Score = 292 bits (747), Expect = 9e-86, Method: Composition-based stats. Identities = 95/318 (30%), Positives = 147/318 (46%), Gaps = 29/318 (9%) Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 + P + + D + L+ I+ LG G FG+V + ++ Sbjct 239 CCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 293 Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 VA+K LK G + +E I++ L H+ +++ E+ + +V EY+ G Sbjct 294 TKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMSKG 348 Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ N + KI D Sbjct 349 SLLDFLKDGEGRALKLPNLVDMAAQVARGMAYIERMNYIHRDLRSANILVGNGLICKIAD 408 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + M + E +ERG R+P P CP ++ LM NCW+ + RPT Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMLNCWKKDPEERPT 512 Query 1162 FENLIPILKTVHEKYQGQ 1179 FE L L+ + Q Sbjct 513 FEYLQGFLEDYFTATEPQ 530 >sp|P10936|YES_XENLA Tyrosine-protein kinase Yes OS=Xenopus laevis OX=8355 GN=yes1 PE=2 SV=3 Length=537 Score = 308 bits (790), Expect = 1e-91, Method: Composition-based stats. Identities = 92/453 (20%), Positives = 159/453 (35%), Gaps = 71/453 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L++ Sbjct 141 VAPADSIQA-EEWYFGKMGRKDAERLLLNPGNQRGTFLVRESETTKGAYSLSIRDW---- 195 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D ++ ++ + I + D F S+++L A C+ L C Sbjct 196 DEVRGDNVKHYKIRKLDNGGYYITTRAQFESLQKLVKHYSEH---ADGLCYRLTTVCP-- 250 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P+T L++ + ++ + LGQG V+ G Sbjct 251 -------------SVKPQTQGLAK-DAWEIPRESLRLDVKLGQGCFGEVWIGTWNGT--- 293 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P + AF + A +M ++ H L ++ Sbjct 294 ----------------------TKVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLY 330 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ G + + + +A Q+A ++Y+E N +H Sbjct 331 AVVSE-EPIYIVTEYMIKGSLLDFLKEGNGKYLKLPQLVDMAAQIADGMAYIERMNYIHR 389 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 390 DLRAANILV-------GDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 441 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 442 -RFTIKSDVWSFGILLTELVAKGRVPYPGMVNREVLEQVERGYRMPCPQRCPESLHELMK 500 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 C +P +RP+F I L Sbjct 501 LCWKKDPDERPTFEYIQSFLEDYFTATEPQYQP 533 Score = 290 bits (743), Expect = 4e-85, Method: Composition-based stats. Identities = 96/315 (30%), Positives = 149/315 (47%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + + + A D + L+ LG+G FG+V + ++ T V Sbjct 242 CYRLTTVCPSVKPQTQGLAKDAWEIPRESLRLDVKLGQGCFGEVWIGTWNGT-----TKV 296 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE I++ L H+ ++ E+ + +V EY+ GSL Sbjct 297 AIKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEYMIKGSLL 351 Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + + L QL+ A QI +GMAY+ +YIHRDL A N+L+ ++ + KI DFGL Sbjct 352 DFLKEGNGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGL 411 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+ Sbjct 412 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVAKGR----- 464 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + E +ERG R+P P +CP ++ LMK CW+ + RPTFE Sbjct 465 ---------VPYPGMVNREVLEQVERGYRMPCPQRCPESLHELMKLCWKKDPDERPTFEY 515 Query 1165 LIPILKTVHEKYQGQ 1179 + L+ + Q Sbjct 516 IQSFLEDYFTATEPQ 530 >sp|P09324|YES_CHICK Tyrosine-protein kinase Yes OS=Gallus gallus OX=9031 GN=YES1 PE=1 SV=3 Length=541 Score = 308 bits (788), Expect = 2e-91, Method: Composition-based stats. Identities = 91/453 (20%), Positives = 160/453 (35%), Gaps = 71/453 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G++L+ S + L++ Sbjct 145 VAPADSIQA-EEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDW---- 199 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D ++ ++ + I + D F S+++L + A C L C Sbjct 200 DEVRGDNVKHYKIRKLDNGGYYITTRAQFESLQKLVKHYREH---ADGLCHKLTTVCP-- 254 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P+T L++ + ++ + LGQG V+ G Sbjct 255 -------------TVKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 297 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P + AF + A +M ++ H L ++ Sbjct 298 ----------------------TKVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLY 334 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTE++ G L +L+ G + + + +A Q+A ++Y+E N +H Sbjct 335 AVVSE-EPIYIVTEFMTKGSLLDFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHR 393 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 394 DLRAANILV-------GDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 445 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 446 -RFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMK 504 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 C +P +RP+F I L Sbjct 505 LCWKKDPDERPTFEYIQSFLEDYFTATEPQYQP 537 Score = 294 bits (753), Expect = 2e-86, Method: Composition-based stats. Identities = 96/315 (30%), Positives = 148/315 (47%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + + + A D + L+ LG+G FG+V + ++ T V Sbjct 246 CHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT-----TKV 300 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL Sbjct 301 AIKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEFMTKGSLL 355 Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ ++ + KI DFGL Sbjct 356 DFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGL 415 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 416 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR----- 468 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + E +ERG R+P P CP ++ LMK CW+ + RPTFE Sbjct 469 ---------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEY 519 Query 1165 LIPILKTVHEKYQGQ 1179 + L+ + Q Sbjct 520 IQSFLEDYFTATEPQ 534 >sp|P13116|SRC2_XENLA Tyrosine-protein kinase Src-2 OS=Xenopus laevis OX=8355 GN=src-b PE=2 SV=3 Length=532 Score = 307 bits (787), Expect = 2e-91, Method: Composition-based stats. Identities = 101/453 (22%), Positives = 162/453 (36%), Gaps = 71/453 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L+V+ Sbjct 136 VAPSDSIQA-EEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDY---- 190 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + L ++ + I + D F S+++L A A C L C Sbjct 191 DASRGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTAVCP-- 245 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 A P+T LS+ + + + LGQG V+ G Sbjct 246 -------------TAKPQTQGLSK-DAWEIPRDSLRLELKLGQGCFGEVWMGTWNGT--- 288 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 RV +K L P AF + A +M ++ H L ++ Sbjct 289 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 325 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH Sbjct 326 AVVSE-EPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHR 384 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 385 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 436 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 437 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPDCPESLHDLMF 495 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 QC +P +RP+F + L Sbjct 496 QCWRKDPEERPTFEYLQAFLEDYFTATEPQYQP 528 Score = 288 bits (738), Expect = 1e-84, Method: Composition-based stats. Identities = 93/315 (30%), Positives = 143/315 (45%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + + + D + L+ LG+G FG+V + ++ T V Sbjct 237 CHRLTAVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTR-----V 291 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL Sbjct 292 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMSKGSLL 346 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 347 DFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 406 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 407 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 459 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P CP ++ LM CW + RPTFE Sbjct 460 ---------VPYPGMVNREVLDQVERGYRMPCPPDCPESLHDLMFQCWRKDPEERPTFEY 510 Query 1165 LIPILKTVHEKYQGQ 1179 L L+ + Q Sbjct 511 LQAFLEDYFTATEPQ 525 >sp|P00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src OS=Gallus gallus OX=9031 GN=SRC PE=1 SV=4 Length=533 Score = 307 bits (787), Expect = 2e-91, Method: Composition-based stats. Identities = 99/453 (22%), Positives = 163/453 (36%), Gaps = 71/453 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L+V+ Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSD----F 191 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + L ++ + I + D F S+++L A A C L C Sbjct 192 DNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + P+T L++ + ++ + LGQG V+ G Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 RV +K L P AF + A +M ++ H L ++ Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 326 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH Sbjct 327 AVVSE-EPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 496 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 QC +P +RP+F + L Sbjct 497 QCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQP 529 Score = 289 bits (740), Expect = 8e-85, Method: Composition-based stats. Identities = 95/315 (30%), Positives = 145/315 (46%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + N+ A D + L+ LG+G FG+V + ++ T V Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 292 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMSKGSLL 347 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW + RPTFE Sbjct 461 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEY 511 Query 1165 LIPILKTVHEKYQGQ 1179 L L+ + Q Sbjct 512 LQAFLEDYFTSTEPQ 526 >sp|P39688|FYN_MOUSE Tyrosine-protein kinase Fyn OS=Mus musculus OX=10090 GN=Fyn PE=1 SV=4 Length=537 Score = 307 bits (787), Expect = 2e-91, Method: Composition-based stats. Identities = 91/453 (20%), Positives = 155/453 (34%), Gaps = 68/453 (15%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G L + +L G +LI S + L++ Sbjct 138 VAPVDSIQA-EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW---- 192 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D M+ ++ + I + D F ++++L RA C L C Sbjct 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSE---RAAGLCCRLVVPCHK- 248 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 L++ + ++ + + LG G V+ G Sbjct 249 ------------GMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGN--- 293 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P +F E A +M ++ H L ++ Sbjct 294 ----------------------TKVAIKTLKPGTMSP-ESFLEEAQIMKKLKHDKLVQLY 330 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ G + + + +A Q+A+ ++Y+E N +H Sbjct 331 AVVSE-EPIYIVTEYMSKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G K++D G+ E I W APE G Sbjct 390 DLRSANILV-------GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 441 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846 + D W FG L E+ G P + E +R +R+P P CP L L Sbjct 442 -RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI 500 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 C +P +RP+F + L Sbjct 501 HCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 533 Score = 289 bits (739), Expect = 1e-84, Method: Composition-based stats. Identities = 108/438 (25%), Positives = 170/438 (39%), Gaps = 50/438 (11%) Query 763 GLGALSREERVERIPWLAP-------ECLPGGANSLSTAMDKWGFG-----ATLLEICFD 810 + E ++AP E G FG + E Sbjct 122 ARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT 181 Query 811 GE------APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 +H+ R+ A + + Q S R Sbjct 182 KGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETL---QQLVQHYSERAAGL 238 Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 + P + + D + L+ I+ LG G FG+V + ++ Sbjct 239 CCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 293 Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 VA+K LK G + +E I++ L H+ +++ E+ + +V EY+ G Sbjct 294 TKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMSKG 348 Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ N + KI D Sbjct 349 SLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIAD 408 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + M + E +ERG R+P P CP ++ LM +CW+ + RPT Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPT 512 Query 1162 FENLIPILKTVHEKYQGQ 1179 FE L L+ + Q Sbjct 513 FEYLQGFLEDYFTATEPQ 530 >sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo sapiens OX=9606 GN=FYN PE=1 SV=3 Length=537 Score = 307 bits (787), Expect = 3e-91, Method: Composition-based stats. Identities = 91/453 (20%), Positives = 155/453 (34%), Gaps = 68/453 (15%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G L + +L G +LI S + L++ Sbjct 138 VAPVDSIQA-EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW---- 192 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D M+ ++ + I + D F ++++L RA C L C Sbjct 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSE---RAAGLCCRLVVPCHK- 248 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 L++ + ++ + + LG G V+ G Sbjct 249 ------------GMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGN--- 293 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P +F E A +M ++ H L ++ Sbjct 294 ----------------------TKVAIKTLKPGTMSP-ESFLEEAQIMKKLKHDKLVQLY 330 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ G + + + +A Q+A+ ++Y+E N +H Sbjct 331 AVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G K++D G+ E I W APE G Sbjct 390 DLRSANILV-------GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 441 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846 + D W FG L E+ G P + E +R +R+P P CP L L Sbjct 442 -RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI 500 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 C +P +RP+F + L Sbjct 501 HCWKKDPEERPTFEYLQSFLEDYFTATEPQYQP 533 Score = 290 bits (743), Expect = 4e-85, Method: Composition-based stats. Identities = 108/438 (25%), Positives = 170/438 (39%), Gaps = 50/438 (11%) Query 763 GLGALSREERVERIPWLAP-------ECLPGGANSLSTAMDKWGFG-----ATLLEICFD 810 + E ++AP E G FG + E Sbjct 122 ARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT 181 Query 811 GE------APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 +H+ R+ A + + Q S R Sbjct 182 KGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETL---QQLVQHYSERAAGL 238 Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 + P + + D + L+ I+ LG G FG+V + ++ Sbjct 239 CCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 293 Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 VA+K LK G + +E I++ L H+ +++ E+ + +V EY+ G Sbjct 294 TKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNKG 348 Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ N + KI D Sbjct 349 SLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIAD 408 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + M + E +ERG R+P P CP ++ LM +CW+ + RPT Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPT 512 Query 1162 FENLIPILKTVHEKYQGQ 1179 FE L L+ + Q Sbjct 513 FEYLQSFLEDYFTATEPQ 530 >sp|Q62844|FYN_RAT Tyrosine-protein kinase Fyn OS=Rattus norvegicus OX=10116 GN=Fyn PE=1 SV=1 Length=537 Score = 307 bits (786), Expect = 3e-91, Method: Composition-based stats. Identities = 91/453 (20%), Positives = 155/453 (34%), Gaps = 68/453 (15%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G L + +L G +LI S + L++ Sbjct 138 VAPVDSIQA-EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW---- 192 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D M+ ++ + I + D F ++++L RA C L C Sbjct 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSE---RAAGLCCRLVVPCHK- 248 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 L++ + ++ + + LG G V+ G Sbjct 249 ------------GMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGN--- 293 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P +F E A +M ++ H L ++ Sbjct 294 ----------------------TKVAIKTLKPGTMSP-ESFLEEAQIMKKLKHDKLVQLY 330 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ G + + + +A Q+A+ ++Y+E N +H Sbjct 331 AVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G K++D G+ E I W APE G Sbjct 390 DLRSANILV-------GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 441 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846 + D W FG L E+ G P + E +R +R+P P CP L L Sbjct 442 -RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI 500 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 C +P +RP+F + L Sbjct 501 HCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 533 Score = 289 bits (739), Expect = 1e-84, Method: Composition-based stats. Identities = 108/438 (25%), Positives = 170/438 (39%), Gaps = 50/438 (11%) Query 763 GLGALSREERVERIPWLAP-------ECLPGGANSLSTAMDKWGFG-----ATLLEICFD 810 + E ++AP E G FG + E Sbjct 122 ARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT 181 Query 811 GE------APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 +H+ R+ A + + Q S R Sbjct 182 KGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETL---QQLVQHYSERAAGL 238 Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 + P + + D + L+ I+ LG G FG+V + ++ Sbjct 239 CCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 293 Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 VA+K LK G + +E I++ L H+ +++ E+ + +V EY+ G Sbjct 294 TKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNKG 348 Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ N + KI D Sbjct 349 SLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIAD 408 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + M + E +ERG R+P P CP ++ LM +CW+ + RPT Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPT 512 Query 1162 FENLIPILKTVHEKYQGQ 1179 FE L L+ + Q Sbjct 513 FEYLQGFLEDYFTATEPQ 530 >sp|A1Y2K1|FYN_PIG Tyrosine-protein kinase Fyn OS=Sus scrofa OX=9823 GN=FYN PE=2 SV=2 Length=537 Score = 307 bits (786), Expect = 3e-91, Method: Composition-based stats. Identities = 91/453 (20%), Positives = 155/453 (34%), Gaps = 68/453 (15%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G L + +L G +LI S + L++ Sbjct 138 VAPVDSIQA-EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW---- 192 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D M+ ++ + I + D F ++++L RA C L C Sbjct 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSE---RAAGLCCRLVVPCHK- 248 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 L++ + ++ + + LG G V+ G Sbjct 249 ------------GMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGN--- 293 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P +F E A +M ++ H L ++ Sbjct 294 ----------------------TKVAIKTLKPGTMSP-ESFLEEAQIMKKLKHDKLVQLY 330 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ G + + + +A Q+A+ ++Y+E N +H Sbjct 331 AVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G K++D G+ E I W APE G Sbjct 390 DLRSANILV-------GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 441 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846 + D W FG L E+ G P + E +R +R+P P CP L L Sbjct 442 -RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI 500 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 C +P +RP+F + L Sbjct 501 HCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 533 Score = 289 bits (739), Expect = 1e-84, Method: Composition-based stats. Identities = 108/438 (25%), Positives = 170/438 (39%), Gaps = 50/438 (11%) Query 763 GLGALSREERVERIPWLAP-------ECLPGGANSLSTAMDKWGFG-----ATLLEICFD 810 + E ++AP E G FG + E Sbjct 122 ARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT 181 Query 811 GE------APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 +H+ R+ A + + Q S R Sbjct 182 KGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETL---QQLVQHYSERAAGL 238 Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 + P + + D + L+ I+ LG G FG+V + ++ Sbjct 239 CCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 293 Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 VA+K LK G + +E I++ L H+ +++ E+ + +V EY+ G Sbjct 294 TKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNKG 348 Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ N + KI D Sbjct 349 SLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIAD 408 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + M + E +ERG R+P P CP ++ LM +CW+ + RPT Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPT 512 Query 1162 FENLIPILKTVHEKYQGQ 1179 FE L L+ + Q Sbjct 513 FEYLQGFLEDYFTATEPQ 530 >sp|A0JNB0|FYN_BOVIN Tyrosine-protein kinase Fyn OS=Bos taurus OX=9913 GN=FYN PE=2 SV=1 Length=537 Score = 307 bits (786), Expect = 3e-91, Method: Composition-based stats. Identities = 91/453 (20%), Positives = 155/453 (34%), Gaps = 68/453 (15%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G L + +L G +LI S + L++ Sbjct 138 VAPVDSIQA-EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW---- 192 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D M+ ++ + I + D F ++++L RA C L C Sbjct 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSE---RAAGLCCRLVVPCHK- 248 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 L++ + ++ + + LG G V+ G Sbjct 249 ------------GMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGN--- 293 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P +F E A +M ++ H L ++ Sbjct 294 ----------------------TKVAIKTLKPGTMSP-ESFLEEAQIMKKLKHDKLVQLY 330 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ G + + + +A Q+A+ ++Y+E N +H Sbjct 331 AVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G K++D G+ E I W APE G Sbjct 390 DLRSANILV-------GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 441 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846 + D W FG L E+ G P + E +R +R+P P CP L L Sbjct 442 -RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI 500 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 C +P +RP+F + L Sbjct 501 HCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 533 Score = 289 bits (739), Expect = 1e-84, Method: Composition-based stats. Identities = 108/438 (25%), Positives = 170/438 (39%), Gaps = 50/438 (11%) Query 763 GLGALSREERVERIPWLAP-------ECLPGGANSLSTAMDKWGFG-----ATLLEICFD 810 + E ++AP E G FG + E Sbjct 122 ARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT 181 Query 811 GE------APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 +H+ R+ A + + Q S R Sbjct 182 KGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETL---QQLVQHYSERAAGL 238 Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 + P + + D + L+ I+ LG G FG+V + ++ Sbjct 239 CCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 293 Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 VA+K LK G + +E I++ L H+ +++ E+ + +V EY+ G Sbjct 294 TKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SEEPIYIVTEYMNKG 348 Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ N + KI D Sbjct 349 SLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIAD 408 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLA+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 409 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-- 464 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + M + E +ERG R+P P CP ++ LM +CW+ + RPT Sbjct 465 ------------VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPT 512 Query 1162 FENLIPILKTVHEKYQGQ 1179 FE L L+ + Q Sbjct 513 FEYLQGFLEDYFTATEPQ 530 >sp|P14084|SRC_AVISS Tyrosine-protein kinase transforming protein Src OS=Avian sarcoma virus (strain S1) OX=11881 GN=V-SRC PE=3 SV=3 Length=568 Score = 308 bits (789), Expect = 3e-91, Method: Composition-based stats. Identities = 100/465 (22%), Positives = 166/465 (36%), Gaps = 71/465 (15%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L+V+ Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSD----F 191 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + L ++ + I + D F S+++L A A C L C Sbjct 192 DNARGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + P+T L++ + ++ + LGQG V+ G Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 RV +K L P AF + A +M ++ H L ++ Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVRLY 326 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH Sbjct 327 AVVSE-EPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 496 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV 891 QC +P +RP+F + L + + D Sbjct 497 QCWRKDPEERPTFEYLQAFLEDYFTSTEPTAVHMATDPGKYTTAH 541 Score = 289 bits (740), Expect = 2e-84, Method: Composition-based stats. Identities = 94/307 (31%), Positives = 143/307 (47%), Gaps = 29/307 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + N+ A D + L+ LG+G FG+V + ++ T V Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 292 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVRLYAVV---SEEPIYIVTEYMSKGSLL 347 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW + RPTFE Sbjct 461 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEY 511 Query 1165 LIPILKT 1171 L L+ Sbjct 512 LQAFLED 518 >sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens OX=9606 GN=SRC PE=1 SV=3 Length=536 Score = 306 bits (785), Expect = 4e-91, Method: Composition-based stats. Identities = 100/453 (22%), Positives = 163/453 (36%), Gaps = 71/453 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L+V+ Sbjct 140 VAPSDSIQA-EEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSD----F 194 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + L ++ + I + D F S+++L A A C L C Sbjct 195 DNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKH---ADGLCHRLTTVCP-- 249 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + P+T L++ + ++ + LGQG V+ G Sbjct 250 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 292 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 RV +K L P AF + A +M ++ H L ++ Sbjct 293 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 329 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH Sbjct 330 AVVSE-EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 388 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 389 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 440 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 441 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 499 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 QC EP +RP+F + L Sbjct 500 QCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQP 532 Score = 289 bits (740), Expect = 9e-85, Method: Composition-based stats. Identities = 95/315 (30%), Positives = 145/315 (46%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + + A D + L+ LG+G FG+V + ++ T V Sbjct 241 CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 295 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL Sbjct 296 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMSKGSLL 350 Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 351 DFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 410 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 411 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 463 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW E RPTFE Sbjct 464 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEY 514 Query 1165 LIPILKTVHEKYQGQ 1179 L L+ + Q Sbjct 515 LQAFLEDYFTSTEPQ 529 >sp|Q9TTY2|FER_CANLF Tyrosine-protein kinase Fer OS=Canis lupus familiaris OX=9615 GN=FER PE=2 SV=1 Length=823 Score = 315 bits (807), Expect = 4e-91, Method: Composition-based stats. Identities = 93/433 (21%), Positives = 180/433 (42%), Gaps = 80/433 (18%) Query 447 IRDGIHGPLLEPFVQAK-LRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKF 505 +D HG + P ++A+ L + G +L+ S P +L+V DG + R F Sbjct 457 EQDWYHGAI--PRIEAQDLLKQQGDFLVRESHGKPGEYVLSVY-----SDGQR----RHF 505 Query 506 PIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMR 565 I+ D + EG G F ++ +L D ++ ++ + S ++++ Sbjct 506 IIQFVDNLYRFEGTG--FSNIPQLI-----------DHHYTTKQVITKK----SGVVLLN 548 Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 + + ++ +++T LG+G VY+G L+ Sbjct 549 P---------IPKDKKWVLNHEDVTLGELLGKGNFGEVYKGILKD--------------- 584 Query 626 PLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 + V +K ++ + F + A ++ Q H ++ + GVC + Sbjct 585 ----------KTAVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPIY 634 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 ++ E V G +LR+++ + + + + AS +SYLE+KN +H ++ RN L+ Sbjct 635 IIMELVPGGDFLSFLRKKKDEIKLKQLVKFSLDAASGMSYLESKNCIHRDLAARNCLV-- 692 Query 745 LGLAEGTSPFIKLSDPGVGL---GALSREERVERIP--WLAPECLPGGANSLSTAMDKWG 799 G + +K+SD G+ G + +++IP W APE L G S+ D W Sbjct 693 -----GENNVLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYG--RYSSESDVWS 745 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857 FG L E G P + + +R +R+ P+ + + +C Y+P RP Sbjct 746 FGILLWETFSLGVCPYPGMTNQQATEQVERGYRISAPQHCPEDIFKIMMKCWDYKPENRP 805 Query 858 SFRTILRDLTRLQ 870 F + ++LT ++ Sbjct 806 KFSELQKELTVIK 818 Score = 280 bits (717), Expect = 7e-79, Method: Composition-based stats. Identities = 94/317 (30%), Positives = 144/317 (45%), Gaps = 25/317 (8%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 I T Q + + P V + + LG+G+FG+V Sbjct 528 IDHHYTTKQVITKKSGVVLLNPIPKDKKWVLNHEDVTLGELLGKGNFGEVYKGILK---- 583 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VAVK K D + + + QE IL+ H +I+K G C + + + ++ME V Sbjct 584 -DKTAVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQR--QPIYIIMELV 640 Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P G +L + I L QL+ F+ GM+YL +++ IHRDLAARN L+ + ++KI Sbjct 641 PGGDFLSFLRKKKDEIKLKQLVKFSLDAASGMSYLESKNCIHRDLAARNCLVGENNVLKI 700 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFG+++ E Y P+ W APE L ++ SDVWSFG+ L+E + Sbjct 701 SDFGMSRQ--EDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFS--- 755 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L MT + TE +ERG R+ P CP +++ +M CW+ + R Sbjct 756 -----------LGVCPYPGMTNQQATEQVERGYRISAPQHCPEDIFKIMMKCWDYKPENR 804 Query 1160 PTFENLIPILKTVHEKY 1176 P F L L + +K Sbjct 805 PKFSELQKELTVIKKKV 821 >sp|P70451|FER_MOUSE Tyrosine-protein kinase Fer OS=Mus musculus OX=10090 GN=Fer PE=1 SV=2 Length=823 Score = 315 bits (806), Expect = 5e-91, Method: Composition-based stats. Identities = 92/435 (21%), Positives = 180/435 (41%), Gaps = 80/435 (18%) Query 447 IRDGIHGPLLEPFVQAK-LRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKF 505 D HG + P ++A+ L + G +L+ S P +L+V DG + R F Sbjct 458 EHDWYHGAI--PRIEAQELLKQQGDFLVRESHGKPGEYVLSVY-----SDGQR----RHF 506 Query 506 PIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMR 565 I+ D + EG G F ++ +L D F+ ++ + S ++++ Sbjct 507 IIQFVDNLYRFEGTG--FSNIPQLI-----------DHHFNTKQVITKK----SGVVLLN 549 Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 + + ++ ++++ LG+G VY+G L+ Sbjct 550 P---------IPKDKKWVLNHEDVSLGELLGKGNFGEVYKGTLKD--------------- 585 Query 626 PLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 + V +K ++ + F + A ++ Q H ++ + GVC + Sbjct 586 ----------KTPVAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVY 635 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 ++ E V G +LR+ + + + + + +A+ + YLE+KN +H ++ RN L+ Sbjct 636 IIMELVPGGDFLTFLRKRKDELKLKQLVRFSLDVAAGMLYLESKNCIHRDLAARNCLV-- 693 Query 745 LGLAEGTSPFIKLSDPGVGL---GALSREERVERIP--WLAPECLPGGANSLSTAMDKWG 799 G + +K+SD G+ G + +++IP W APE L G S+ D W Sbjct 694 -----GENNTLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYG--RYSSESDVWS 746 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857 FG L E G P + + +R +R+ P+ ++ T+ +C Y+P RP Sbjct 747 FGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQNCPEEVFTIMMKCWDYKPENRP 806 Query 858 SFRTILRDLTRLQPH 872 F + ++LT ++ Sbjct 807 KFNDLHKELTVIKKM 821 Score = 277 bits (708), Expect = 1e-77, Method: Composition-based stats. Identities = 91/315 (29%), Positives = 141/315 (45%), Gaps = 25/315 (8%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 I Q + + P V + + LG+G+FG+V Sbjct 529 IDHHFNTKQVITKKSGVVLLNPIPKDKKWVLNHEDVSLGELLGKGNFGEVYKGTLK---- 584 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VA+K K D + + + QE IL+ H +I+K G C + + + ++ME V Sbjct 585 -DKTPVAIKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQR--QPVYIIMELV 641 Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P G +L + + L QL+ F+ + GM YL +++ IHRDLAARN L+ + +KI Sbjct 642 PGGDFLTFLRKRKDELKLKQLVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTLKI 701 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFG+++ E Y P+ W APE L ++ SDVWSFG+ L+E + Sbjct 702 SDFGMSRQ--EDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFS--- 756 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L MT + E +ERG R+ P CP EV+ +M CW+ + R Sbjct 757 -----------LGVCPYPGMTNQQAREQVERGYRMSAPQNCPEEVFTIMMKCWDYKPENR 805 Query 1160 PTFENLIPILKTVHE 1174 P F +L L + + Sbjct 806 PKFNDLHKELTVIKK 820 >sp|P14085|SRC_AVIST Tyrosine-protein kinase transforming protein Src OS=Avian sarcoma virus (strain S2) OX=11882 GN=V-SRC PE=3 SV=3 Length=557 Score = 307 bits (786), Expect = 6e-91, Method: Composition-based stats. Identities = 98/439 (22%), Positives = 162/439 (37%), Gaps = 71/439 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L+V+ Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSD----F 191 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + L ++ + I + D F S+++L A A C L C Sbjct 192 DNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + P+T L++ + ++ + LGQG V+ G Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 RV +K L P AF + A +M ++ H L ++ Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 326 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH Sbjct 327 AVVSE-EPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 496 Query 847 QCLTYEPTQRPSFRTILRD 865 QC +P +RP+F + Sbjct 497 QCWRKDPEERPTFEYLQAF 515 Score = 288 bits (738), Expect = 3e-84, Method: Composition-based stats. Identities = 94/307 (31%), Positives = 143/307 (47%), Gaps = 29/307 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + N+ A D + L+ LG+G FG+V + ++ T V Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 292 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMSKGSLL 347 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW + RPTFE Sbjct 461 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEY 511 Query 1165 LIPILKT 1171 L L+ Sbjct 512 LQAFLED 518 >sp|P00525|SRC_AVISR Tyrosine-protein kinase transforming protein Src OS=Avian sarcoma virus (strain rASV1441) OX=11894 GN=V-SRC PE=1 SV=3 Length=526 Score = 305 bits (782), Expect = 7e-91, Method: Composition-based stats. Identities = 98/437 (22%), Positives = 162/437 (37%), Gaps = 71/437 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L+V+ Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSD----F 191 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + L ++ + I + D F S+++L A A C L C Sbjct 192 DNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + P+T L++ + ++ + LGQG V+ G Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 RV +K L P AF + A +M ++ H L ++ Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 326 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH Sbjct 327 AVVSE-EPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMC 496 Query 847 QCLTYEPTQRPSFRTIL 863 QC +P +RP+F + Sbjct 497 QCWRRDPEERPTFEYLQ 513 Score = 284 bits (727), Expect = 5e-83, Method: Composition-based stats. Identities = 94/305 (31%), Positives = 142/305 (47%), Gaps = 29/305 (10%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + N+ A D + L+ LG+G FG+V + ++ T V Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 292 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMSKGSLL 347 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW + RPTFE Sbjct 461 ---------VPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMCQCWRRDPEERPTFEY 511 Query 1165 LIPIL 1169 L L Sbjct 512 LQAQL 516 >sp|P63185|SRC_RSVSE Tyrosine-protein kinase transforming protein Src OS=Rous sarcoma virus subgroup E (strain Schmidt-Ruppin) OX=270623 GN=V-SRC PE=1 SV=3 Length=526 Score = 305 bits (781), Expect = 1e-90, Method: Composition-based stats. Identities = 98/437 (22%), Positives = 162/437 (37%), Gaps = 71/437 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L+V+ Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSD----F 191 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + L ++ + I + D F S+++L A A C L C Sbjct 192 DNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + P+T L++ + ++ + LGQG V+ G Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 RV +K L P AF + A +M ++ H L ++ Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHKKLVQLY 326 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +V EY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH Sbjct 327 AVVSE-EPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L S Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMS 496 Query 847 QCLTYEPTQRPSFRTIL 863 QC +P +RP+F + Sbjct 497 QCWRRDPEERPTFEYLQ 513 Score = 283 bits (725), Expect = 9e-83, Method: Composition-based stats. Identities = 93/305 (30%), Positives = 143/305 (47%), Gaps = 29/305 (10%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + N+ A D + L+ LG+G FG+V + ++ T V Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 292 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L H+ +++ E+ + +V+EY+ GSL Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHKKLVQLYAVV---SEEPIYIVIEYMSKGSLL 347 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW + RPTFE Sbjct 461 ---------VPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMSQCWRRDPEERPTFEY 511 Query 1165 LIPIL 1169 L L Sbjct 512 LQAQL 516 >sp|P15054|SRC_AVIS2 Tyrosine-protein kinase transforming protein Src OS=Avian sarcoma virus (strain PR2257) OX=11879 GN=V-SRC PE=3 SV=3 Length=587 Score = 307 bits (786), Expect = 1e-90, Method: Composition-based stats. Identities = 98/439 (22%), Positives = 162/439 (37%), Gaps = 71/439 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L+V+ Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSD----F 191 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + L ++ + I + D F S+++L A A C L C Sbjct 192 DNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + P+T L++ + ++ + LGQG V+ G Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 RV +K L P AF + A +M ++ H L ++ Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 326 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH Sbjct 327 AVVSE-EPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 496 Query 847 QCLTYEPTQRPSFRTILRD 865 QC +P +RP+F + Sbjct 497 QCWRKDPEERPTFEYLQAF 515 Score = 291 bits (745), Expect = 6e-85, Method: Composition-based stats. Identities = 95/318 (30%), Positives = 146/318 (46%), Gaps = 29/318 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + N+ A D + L+ LG+G FG+V + ++ T V Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 292 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMSKGSLL 347 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW + RPTFE Sbjct 461 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEY 511 Query 1165 LIPILKTVHEKYQGQAPS 1182 L L+ + P+ Sbjct 512 LQAFLEDYFTSTEPPVPA 529 >sp|P09760|FER_RAT Tyrosine-protein kinase Fer OS=Rattus norvegicus OX=10116 GN=Fer PE=1 SV=2 Length=823 Score = 313 bits (803), Expect = 1e-90, Method: Composition-based stats. Identities = 92/433 (21%), Positives = 179/433 (41%), Gaps = 80/433 (18%) Query 447 IRDGIHGPLLEPFVQAK-LRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKF 505 D HG + P ++A+ L + G +L+ S P +L+V DG + R F Sbjct 458 EHDWYHGAI--PRIEAQELLKQQGDFLVRESHGKPGEYVLSVY-----SDGQR----RHF 506 Query 506 PIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMR 565 I+ D + EG G F ++ +L D F+ ++ + S ++++ Sbjct 507 IIQFVDNLYRFEGTG--FSNIPQLI-----------DHHFNTKQVITKK----SGVVLLN 549 Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 + + ++ ++++ LG+G VY+G L+ Sbjct 550 P---------IPKDKKWVLNHEDVSLGELLGKGNFGEVYKGTLKD--------------- 585 Query 626 PLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 + V +K ++ + F + A ++ Q H ++ + GVC + Sbjct 586 ----------KTPVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVY 635 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 ++ E V G +LR+ + + + + + +A+ + YLE KN +H ++ RN L+ Sbjct 636 IIMELVPGGDFLSFLRKRKDELKLKQLVRFSLDVAAGMLYLEGKNCIHRDLAARNCLV-- 693 Query 745 LGLAEGTSPFIKLSDPGVGL---GALSREERVERIP--WLAPECLPGGANSLSTAMDKWG 799 G + +K+SD G+ G + +++IP W APE L G S+ D W Sbjct 694 -----GENNTLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYG--RYSSESDVWS 746 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857 FG L E G P + + +R +R+ P+ ++ T+ +C Y+P RP Sbjct 747 FGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQNCPEEIFTIMMKCWDYKPENRP 806 Query 858 SFRTILRDLTRLQ 870 F + ++LT ++ Sbjct 807 KFSDLHKELTAIK 819 Score = 279 bits (714), Expect = 2e-78, Method: Composition-based stats. Identities = 92/316 (29%), Positives = 141/316 (45%), Gaps = 25/316 (8%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 I Q + + P V + + LG+G+FG+V Sbjct 529 IDHHFNTKQVITKKSGVVLLNPIPKDKKWVLNHEDVSLGELLGKGNFGEVYKGTLK---- 584 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VAVK K D + + + QE IL+ H +I+K G C + + + ++ME V Sbjct 585 -DKTPVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQR--QPVYIIMELV 641 Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P G +L + + L QL+ F+ + GM YL ++ IHRDLAARN L+ + +KI Sbjct 642 PGGDFLSFLRKRKDELKLKQLVRFSLDVAAGMLYLEGKNCIHRDLAARNCLVGENNTLKI 701 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFG+++ E Y P+ W APE L ++ SDVWSFG+ L+E + Sbjct 702 SDFGMSRQ--EDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFS--- 756 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L MT + E +ERG R+ P CP E++ +M CW+ + R Sbjct 757 -----------LGVCPYPGMTNQQAREQVERGYRMSAPQNCPEEIFTIMMKCWDYKPENR 805 Query 1160 PTFENLIPILKTVHEK 1175 P F +L L + +K Sbjct 806 PKFSDLHKELTAIKKK 821 >sp|P05480|SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src OS=Mus musculus OX=10090 GN=Src PE=1 SV=5 Length=535 Score = 305 bits (780), Expect = 2e-90, Method: Composition-based stats. Identities = 99/453 (22%), Positives = 163/453 (36%), Gaps = 71/453 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L+V+ Sbjct 139 VAPSDSIQA-EEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSD----F 193 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + L ++ + I + D F S+++L A A C L C Sbjct 194 DNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKH---ADGLCHRLTTVCP-- 248 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + P+T L++ + ++ + LGQG V+ G Sbjct 249 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 291 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 RV +K L P AF + A +M ++ H L ++ Sbjct 292 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 328 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ E G + + + ++ Q+AS ++Y+E N VH Sbjct 329 AVVSE-EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHR 387 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 388 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 439 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 440 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 498 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 QC EP +RP+F + L Sbjct 499 QCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQP 531 Score = 288 bits (736), Expect = 3e-84, Method: Composition-based stats. Identities = 94/315 (30%), Positives = 145/315 (46%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + + A D + L+ LG+G FG+V + ++ T V Sbjct 240 CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 294 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL Sbjct 295 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMNKGSLL 349 Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + + L QL+ + QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 350 DFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 409 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 410 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 462 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW E RPTFE Sbjct 463 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEY 513 Query 1165 LIPILKTVHEKYQGQ 1179 L L+ + Q Sbjct 514 LQAFLEDYFTSTEPQ 528 >sp|Q9WUD9|SRC_RAT Proto-oncogene tyrosine-protein kinase Src OS=Rattus norvegicus OX=10116 GN=Src PE=1 SV=4 Length=536 Score = 305 bits (780), Expect = 2e-90, Method: Composition-based stats. Identities = 99/453 (22%), Positives = 163/453 (36%), Gaps = 71/453 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L+V+ Sbjct 140 VAPSDSIQA-EEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSD----F 194 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + L ++ + I + D F S+++L A A C L C Sbjct 195 DNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKH---ADGLCHRLTTVCP-- 249 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + P+T L++ + ++ + LGQG V+ G Sbjct 250 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 292 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 RV +K L P AF + A +M ++ H L ++ Sbjct 293 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 329 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ E G + + + ++ Q+AS ++Y+E N VH Sbjct 330 AVVSE-EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHR 388 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 389 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 440 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 441 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 499 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 QC EP +RP+F + L Sbjct 500 QCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQP 532 Score = 288 bits (736), Expect = 3e-84, Method: Composition-based stats. Identities = 94/315 (30%), Positives = 145/315 (46%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + + A D + L+ LG+G FG+V + ++ T V Sbjct 241 CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 295 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL Sbjct 296 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMNKGSLL 350 Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + + L QL+ + QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 351 DFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 410 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 411 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 463 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW E RPTFE Sbjct 464 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEY 514 Query 1165 LIPILKTVHEKYQGQ 1179 L L+ + Q Sbjct 515 LQAFLEDYFTSTEPQ 529 >sp|P07947|YES_HUMAN Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 Length=543 Score = 305 bits (780), Expect = 3e-90, Method: Composition-based stats. Identities = 89/453 (20%), Positives = 159/453 (35%), Gaps = 71/453 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G++L+ S + L++ Sbjct 147 VAPADSIQA-EEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDW---- 201 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D ++ ++ + I + D F ++++L A C L C Sbjct 202 DEIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEH---ADGLCHKLTTVCP-- 256 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P+T L++ + ++ + LGQG V+ G Sbjct 257 -------------TVKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 299 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P + AF + A +M ++ H L ++ Sbjct 300 ----------------------TKVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLY 336 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTE++ G L +L+ G + + + +A Q+A ++Y+E N +H Sbjct 337 AVVSE-EPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHR 395 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 396 DLRAANILV-------GENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 447 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG E+ G P E +R +R+P P CP+ L L + Sbjct 448 -RFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMN 506 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 C +P +RP+F I L Sbjct 507 LCWKKDPDERPTFEYIQSFLEDYFTATEPQYQP 539 Score = 289 bits (739), Expect = 2e-84, Method: Composition-based stats. Identities = 94/315 (30%), Positives = 145/315 (46%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + + + A D + L+ LG+G FG+V + ++ T V Sbjct 248 CHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT-----TKV 302 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL Sbjct 303 AIKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEFMSKGSLL 357 Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ + + KI DFGL Sbjct 358 DFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGL 417 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ EL+T Sbjct 418 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGR----- 470 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + E +ERG R+P P CP ++ LM CW+ + RPTFE Sbjct 471 ---------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEY 521 Query 1165 LIPILKTVHEKYQGQ 1179 + L+ + Q Sbjct 522 IQSFLEDYFTATEPQ 536 >sp|Q05876|FYN_CHICK Tyrosine-protein kinase Fyn OS=Gallus gallus OX=9031 GN=FYN PE=1 SV=2 Length=534 Score = 304 bits (779), Expect = 3e-90, Method: Composition-based stats. Identities = 96/453 (21%), Positives = 164/453 (36%), Gaps = 71/453 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G L + +L G +LI S + L++ Sbjct 138 VAPVDSIQA-EEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDW---- 192 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D M+ ++ + I + D F ++++L +A CF+L Sbjct 193 DDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSE---KADGLCFNLT------ 243 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + +P+T+ L++ V + + LGQG V+ G Sbjct 244 ---------VIATNNTPQTVGLAK-DAWEVARDSLFLEQKLGQGCFAEVWRGTWNGN--- 290 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P +F E A +M ++ H L ++ Sbjct 291 ----------------------TKVAIKTLKPGTMSP-ESFLEEAQIMKKLKHDKLVQLY 327 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V R P +VTEY+ G L ++L+ G + + + +A Q+A+ ++Y+E N +H Sbjct 328 AVVSRRP-IYIVTEYMSKGSLLIFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 386 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G K++D G+ E I W APE G Sbjct 387 DLRSANILV-------GNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 438 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846 + D W FG L E+ G P + E +R +R+P P CP L L Sbjct 439 -RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMI 497 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 C +P +RP+F + L Sbjct 498 HCWKKDPEERPTFEYLQGFLEDYFTATEPQYQP 530 Score = 278 bits (711), Expect = 9e-81, Method: Composition-based stats. Identities = 106/432 (25%), Positives = 166/432 (38%), Gaps = 41/432 (9%) Query 763 GLGALSREERVERIPWLAP-------ECLPGGANSLSTAMDKWGFG-----ATLLEICFD 810 + E ++AP E G FG + E Sbjct 122 ARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETT 181 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 A S + +H +T++ Q + D Sbjct 182 KGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSEKADGLCFN 241 Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 +A T A D + L + LG+G F +V ++ VA+K Sbjct 242 LTVIATNNTPQTVGLAKDAWEVARDSLFLEQKLGQGCFAEVWRGTWNG-----NTKVAIK 296 Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 LK G + +E I++ L H+ +++ + + +V EY+ GSL +L Sbjct 297 TLKP--GTMSPESFLEEAQIMKKLKHDKLVQLYAVV---SRRPIYIVTEYMSKGSLLIFL 351 Query 991 PR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ N + KI DFGLA+ Sbjct 352 KDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARL 411 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 412 IEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR-------- 461 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + M + E +ERG R+P P CP ++ LM +CW+ + RPTFE L Sbjct 462 ------VPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQG 515 Query 1168 ILKTVHEKYQGQ 1179 L+ + Q Sbjct 516 FLEDYFTATEPQ 527 >sp|F1RDG9|FYNB_DANRE Tyrosine-protein kinase fynb OS=Danio rerio OX=7955 GN=fynb PE=2 SV=1 Length=544 Score = 305 bits (780), Expect = 3e-90, Method: Composition-based stats. Identities = 90/465 (19%), Positives = 155/465 (33%), Gaps = 67/465 (14%) Query 426 LTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYR 482 LT + Y+ P + D G L + +L G +LI S + Sbjct 132 LTTGGTGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSTGNPRGTFLIRESETTKGA 191 Query 483 LILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGD 542 L++ D ++ ++ + I + D F ++++L RA Sbjct 192 FSLSIRDW----DDVKGDHVKHYKIRKLDSGGYYITTRAQFETLQQLVQHYTE---RAAG 244 Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTN 602 C L C L++ + ++ + + LG G Sbjct 245 LCCRLVVPCHK-------------GMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGE 291 Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662 V+ G +V +K L P +F E A +M Sbjct 292 VWMGTWNGN-------------------------TKVAIKTLKPGTMSP-ESFLEEAQIM 325 Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASA 721 ++ H L ++ V +VTEY+ G L +L+ G + + + +A Q+A Sbjct 326 KKLRHDKLVQLYAVVSE-EPIYIVTEYMGKGSLLDFLKDGEGRALKLPNLVDMAAQVAGG 384 Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RI 776 ++Y+E N +H ++ NIL+ G S K++D G+ E I Sbjct 385 MAYIERMNYIHRDLRSANILV-------GDSLVCKIADFGLARLIEDNEYTARQGAKFPI 437 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--P 834 W APE G + D W FG L E+ G P + E +R +R+ P Sbjct 438 KWTAPEAALYG--KFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMQCP 495 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 + L L QC + +RP+F + L Sbjct 496 QDCPSSLHELMVQCWKKDAEERPTFEYLQAFLEDYFTATEPQYQP 540 Score = 286 bits (732), Expect = 1e-83, Method: Composition-based stats. Identities = 94/318 (30%), Positives = 146/318 (46%), Gaps = 29/318 (9%) Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 + P + + D + L+ I+ LG G FG+V + ++ Sbjct 246 CCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNG-----N 300 Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 VA+K LK G + +E I++ L H+ +++ E+ + +V EY+ G Sbjct 301 TKVAIKTLKP--GTMSPESFLEEAQIMKKLRHDKLVQLYAVV---SEEPIYIVTEYMGKG 355 Query 985 SLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 SL D+L ++ L L+ A Q+ GMAY+ +YIHRDL + N+L+ + + KI D Sbjct 356 SLLDFLKDGEGRALKLPNLVDMAAQVAGGMAYIERMNYIHRDLRSANILVGDSLVCKIAD 415 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLA+ + + Y R+ P+ W APE KF SDVWSFG+ L EL+T Sbjct 416 FGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGKFTIKSDVWSFGILLTELVTKGR-- 471 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + M + E +ERG R+ P CP ++ LM CW+ +A RPT Sbjct 472 ------------VPYPGMNNREVLEQVERGYRMQCPQDCPSSLHELMVQCWKKDAEERPT 519 Query 1162 FENLIPILKTVHEKYQGQ 1179 FE L L+ + Q Sbjct 520 FEYLQAFLEDYFTATEPQ 537 >sp|P31693|SRC_RSVPA Tyrosine-protein kinase transforming protein Src OS=Rous sarcoma virus (strain PA101T) OX=31667 GN=V-SRC PE=3 SV=3 Length=523 Score = 303 bits (777), Expect = 3e-90, Method: Composition-based stats. Identities = 113/559 (20%), Positives = 189/559 (34%), Gaps = 82/559 (15%) Query 328 PVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAVGQPAD-RPREPLWAYFCDFRDITHV 386 P + + E S G P + K A F DF V Sbjct 11 PSQRRRSLEPPDSTHHGGFPASQTPNKTAAPDTHRTPSRSFGTVATELKLFGDFNTSDTV 70 Query 387 VLKEHC------VSIHRQDNKCLELSLPSR-AAALSFVSLVDGYF----RLTADSSHYLC 435 + V+ +E L + L V+ +G + LT + Y+ Sbjct 71 TSPQRAGALAGSVTTFGTRESRIETDLSFKKRERLQIVNNTEGTWWLAHSLTTGQTGYIP 130 Query 436 HEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQ 492 P + + G + L + G +L+ S + L+V+ Sbjct 131 SNYVAPSDSIQAEEWYFGKITRRESGRLLLNPENPRGTFLVRESETTKGAYCLSVSD--- 187 Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552 D + L ++ + I + D F S+++L A A C L C Sbjct 188 -FDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP 243 Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 + P+T L++ + ++ + LGQG V+ G Sbjct 244 ---------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGYFGEVWMGTWNGT- 286 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672 RV +K L P AF + A +M ++ H L Sbjct 287 ------------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQ 321 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLV 731 ++ + +V EY+ G L +L+ E G + + + +A Q+AS ++Y+E N V Sbjct 322 LYAMVSE-EPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVEMAAQIASGMAYVERMNYV 380 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPG 786 H ++ NIL+ G + K++D G+ E + W APE Sbjct 381 HRDLRAANILV-------GENLVCKVADFGLARLIEDNEYTARPGARFPVKWTAPEAALY 433 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATL 844 G + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 434 G--RFTIKSDVWSFGILLTELTTKGRVPYPGMVNGEVLDRVERGYRMPCPPECPESLHDL 491 Query 845 TSQCLTYEPTQRPSFRTIL 863 QC +P +RP+F + Sbjct 492 MCQCWRKDPEERPTFEYLQ 510 Score = 281 bits (718), Expect = 6e-82, Method: Composition-based stats. Identities = 95/305 (31%), Positives = 143/305 (47%), Gaps = 29/305 (10%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + N+ A D + L+ LG+G+FG+V + ++ T V Sbjct 235 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGYFGEVWMGTWNGTTR-----V 289 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL Sbjct 290 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAMV---SEEPIYIVIEYMSKGSLL 344 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 345 DFLKGEMGKYLRLPQLVEMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 404 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R PV W APE +F SDVWSFG+ L EL T Sbjct 405 ARLIEDNE--YTARPGARFPVKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 457 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW + RPTFE Sbjct 458 ---------VPYPGMVNGEVLDRVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEY 508 Query 1165 LIPIL 1169 L L Sbjct 509 LQAQL 513 >sp|P00524|SRC_RSVSA Tyrosine-protein kinase transforming protein Src OS=Rous sarcoma virus subgroup A (strain Schmidt-Ruppin) OX=269446 GN=V-SRC PE=1 SV=6 Length=526 Score = 303 bits (776), Expect = 5e-90, Method: Composition-based stats. Identities = 97/437 (22%), Positives = 161/437 (37%), Gaps = 71/437 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L+V+ Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSD----F 191 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + L ++ + I + D F S+++L A A C L C Sbjct 192 DNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + P+T L++ + ++ + LGQG V+ G Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 RV +K L P AF + A +M ++ H L ++ Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 326 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +V EY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH Sbjct 327 AVVSE-EPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMC 496 Query 847 QCLTYEPTQRPSFRTIL 863 QC +P +RP+F + Sbjct 497 QCWRRDPEERPTFEYLQ 513 Score = 283 bits (723), Expect = 2e-82, Method: Composition-based stats. Identities = 94/305 (31%), Positives = 143/305 (47%), Gaps = 29/305 (10%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + N+ A D + L+ LG+G FG+V + ++ T V Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR-----V 292 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVIEYMSKGSLL 347 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW + RPTFE Sbjct 461 ---------VPYPGMGNGEVLDRVERGYRMPCPPECPESLHDLMCQCWRRDPEERPTFEY 511 Query 1165 LIPIL 1169 L L Sbjct 512 LQAQL 516 >sp|P17713|STK_HYDVU Tyrosine-protein kinase STK OS=Hydra vulgaris OX=6087 GN=STK PE=2 SV=1 Length=509 Score = 302 bits (774), Expect = 6e-90, Method: Composition-based stats. Identities = 97/486 (20%), Positives = 174/486 (36%), Gaps = 78/486 (16%) Query 393 VSIHRQDNKCLELSLPSRAAALSFVSLVDG---YFR-LTADSSHYLCHEVAPPRLVMSIR 448 V+++ + + E + L ++ DG Y R L +S Y+ P Sbjct 65 VALYDYEARISEDLSFKKGERLQIINTADGDWWYARSLITNSEGYIPSTYVAPEKSYEAE 124 Query 449 DGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKF 505 + G + + +L G +LI + + L+V D ++ R+RK Sbjct 125 EWYFGDVKRAEAEKRLMVRGLPSGTFLIRKAETAVGNFSLSVRD----GDSVKHYRVRKL 180 Query 506 PIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMR 565 D F S+ EL A +L C Sbjct 181 -----DTGGYFITTRAPFNSLYELVQHYTKD---ADGLVCALTLPCP------------- 219 Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 + P T +++ + ++ + LG G V+ G Sbjct 220 --KDKPVTGGIAK-DAWEIPRESLRLNRKLGAGQFGEVWAGVW----------------- 259 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 +V +K L P A +F + A +M ++ H HL ++ +C + Sbjct 260 --------NNTTQVAVKTLKPGTMSPA-SFLDEAGVMKKLRHKHLVQLYAICSDREPIYI 310 Query 686 VTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 VTEY+ G L +L + G ++ + + +A Q+AS +++LE + +H ++ RNIL+ Sbjct 311 VTEYMSGGSLLDYLSKGEGVNLQLPTLIDMAAQVASGMAFLEAQGYIHRDLAARNILV-- 368 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWG 799 G + K++D G+ E I W APE N + D W Sbjct 369 -----GENYICKVADFGLARLIEDDEYTAHEGAKFPIKWTAPEAAL--YNRFTIKSDVWS 421 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRP 857 FG + EI G P + ++ ++ +R+P CP L + Q +P RP Sbjct 422 FGILMAEIVTKGRIPYPGMTNAQTIAEVEKGYRMPIMPGCPEPLYNIMLQTWNKDPENRP 481 Query 858 SFRTIL 863 +F + Sbjct 482 TFDYLQ 487 Score = 277 bits (709), Expect = 9e-81, Method: Composition-based stats. Identities = 93/285 (33%), Positives = 143/285 (50%), Gaps = 28/285 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + L+ R LG G FG+V ++ T VAVK LK G + + E Sbjct 233 WEIPRESLRLNRKLGAGQFGEVWAGVWNNT-----TQVAVKTLKP--GTMSPASFLDEAG 285 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQ 1006 +++ L H+H+++ C D+ + + +V EY+ GSL DYL + ++ L L+ A Q Sbjct 286 VMKKLRHKHLVQLYAICSDR--EPIYIVTEYMSGGSLLDYLSKGEGVNLQLPTLIDMAAQ 343 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 + GMA+L AQ YIHRDLAARN+L+ + + K+ DFGLA+ + + Y E P+ Sbjct 344 VASGMAFLEAQGYIHRDLAARNILVGENYICKVADFGLARLIEDDE--YTAHEGAKFPIK 401 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE +F SDVWSFG+ + E++T I MT + Sbjct 402 WTAPEAALYNRFTIKSDVWSFGILMAEIVTKGR--------------IPYPGMTNAQTIA 447 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +E+G R+P CP +Y++M W + RPTF+ L +L+ Sbjct 448 EVEKGYRMPIMPGCPEPLYNIMLQTWNKDPENRPTFDYLQGVLED 492 >sp|A1A5H8|YES_DANRE Tyrosine-protein kinase yes OS=Danio rerio OX=7955 GN=yes1 PE=1 SV=1 Length=546 Score = 303 bits (777), Expect = 7e-90, Method: Composition-based stats. Identities = 91/453 (20%), Positives = 158/453 (35%), Gaps = 71/453 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L++ Sbjct 150 VAPADSIQA-EEWYFGKMGRKDAERLLLLPGNQRGTFLVRESETTKGAYSLSIRDW---- 204 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D M+ ++ + I + D F ++++L A C+ L C Sbjct 205 DEMKGDNVKHYKIRKLDSGGYYITTRAQFDTLQKLVKHYTEH---ADGLCYRLTTVCP-- 259 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P+T L++ + ++ + LGQG V+ G Sbjct 260 -------------TVKPQTQGLAK-DAWEIPRESLRLELKLGQGCFGEVWMGTWNGT--- 302 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P AF + A +M ++ H L ++ Sbjct 303 ----------------------TKVAIKTLKPGTMSP-EAFLQEAQIMKKLRHDKLVPLY 339 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ G + + + +A Q+A ++++E N +H Sbjct 340 AVVSE-EPIYIVTEYMGKGSLLDFLKEGEGKYLKLPQLVDMAAQIADGMAFIERMNYIHR 398 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 399 DLRAANILV-------GDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 450 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L + Sbjct 451 -RFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHEMMR 509 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 C EP +RP+F I L Sbjct 510 LCWKKEPDERPTFEYIQSFLEDYFTATEPQYQP 542 Score = 290 bits (741), Expect = 7e-85, Method: Composition-based stats. Identities = 95/315 (30%), Positives = 148/315 (47%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + + + A D + L+ LG+G FG+V + ++ T V Sbjct 251 CYRLTTVCPTVKPQTQGLAKDAWEIPRESLRLELKLGQGCFGEVWMGTWNGT-----TKV 305 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE I++ L H+ ++ E+ + +V EY+ GSL Sbjct 306 AIKTLKP--GTMSPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEYMGKGSLL 360 Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI +GMA++ +YIHRDL A N+L+ ++ + KI DFGL Sbjct 361 DFLKEGEGKYLKLPQLVDMAAQIADGMAFIERMNYIHRDLRAANILVGDNLVCKIADFGL 420 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 421 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR----- 473 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + E +ERG R+P P CP ++ +M+ CW+ E RPTFE Sbjct 474 ---------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHEMMRLCWKKEPDERPTFEY 524 Query 1165 LIPILKTVHEKYQGQ 1179 + L+ + Q Sbjct 525 IQSFLEDYFTATEPQ 539 >sp|P00527|YES_AVISY Tyrosine-protein kinase transforming protein Yes (Fragment) OS=Y73 avian sarcoma virus OX=11884 GN=V-YES PE=3 SV=2 Length=528 Score = 303 bits (776), Expect = 7e-90, Method: Composition-based stats. Identities = 89/439 (20%), Positives = 158/439 (36%), Gaps = 71/439 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G++L+ S + L++ Sbjct 137 VAPADSIEA-EEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDW---- 191 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D ++ ++ + I + D F S+++L + A C L C Sbjct 192 DEVRGDNVKHYKIRKLDNGGYYITTRAQFESLQKLVKHSREH---ADGLCHKLTTVCP-- 246 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P+T L++ + ++ + LGQG V+ G Sbjct 247 -------------TVKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 289 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L + AF + A +M ++ H L ++ Sbjct 290 ----------------------TKVAIKTLKLGTM-MPEAFLQEAQIMKKLRHDKLVPLY 326 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTE++ G L +L+ G + + + +A Q+A ++Y+E N +H Sbjct 327 AVVSE-EPIYIVTEFMTKGSLLDFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHR 385 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 386 DLRAANILV-------GDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 438 -RFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMK 496 Query 847 QCLTYEPTQRPSFRTILRD 865 C +P +RP+F I Sbjct 497 LCWKKDPDERPTFEYIQSF 515 Score = 293 bits (751), Expect = 2e-86, Method: Composition-based stats. Identities = 95/307 (31%), Positives = 146/307 (48%), Gaps = 29/307 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + + + A D + L+ LG+G FG+V + ++ T V Sbjct 238 CHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT-----TKV 292 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL Sbjct 293 AIKTLKL--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEFMTKGSLL 347 Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ ++ + KI DFGL Sbjct 348 DFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + E +ERG R+P P CP ++ LMK CW+ + RPTFE Sbjct 461 ---------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEY 511 Query 1165 LIPILKT 1171 + L+ Sbjct 512 IQSFLED 518 >sp|P27447|YES_XIPHE Tyrosine-protein kinase Yes OS=Xiphophorus hellerii OX=8084 GN=yes PE=2 SV=3 Length=544 Score = 303 bits (776), Expect = 9e-90, Method: Composition-based stats. Identities = 95/453 (21%), Positives = 156/453 (34%), Gaps = 71/453 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + S + G L + L E G +LI S + L++ Sbjct 148 VAPADSIQS-EEWYFGKLSRKDTERLLLLPGNERGTFLIRESETTKGAYSLSLRDW---- 202 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + + + I + D F S++ L C+ L C Sbjct 203 DETKGDNCKHYKIRKLDNGGYYITTRTQFMSLQMLVKHYTEH---VDGLCYKLTTVCP-- 257 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + P+T +++ + ++ + LGQG V+ G Sbjct 258 -------------QVKPQTQGIAK-DAWEIPRESLRLDVRLGQGCFGEVWMGTWNGT--- 300 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P AF E A +M ++ H L ++ Sbjct 301 ----------------------TKVAIKTLKPGTMSP-EAFLEEAQIMKKLRHDKLVPLY 337 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTE++ G L +L+ G H+ + + +A Q+A ++++E N +H Sbjct 338 AVVSE-EPIYIVTEFMGKGSLLDFLKEGDGKHLKLPQLVDMASQIADGMAFIERMNYIHR 396 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+A + K++D G+ E I W APE G Sbjct 397 DLRAANILVA-------DNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 448 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E R +R+P P CP+ L + Sbjct 449 -RFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVDRGYRMPCPQGCPESLHEMMR 507 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 QC EP +RP+F I L Sbjct 508 QCWKKEPDERPTFEYIQSFLEDYFTATEPQYQP 540 Score = 288 bits (736), Expect = 3e-84, Method: Composition-based stats. Identities = 92/315 (29%), Positives = 148/315 (47%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + + + A D + L+ LG+G FG+V + ++ T V Sbjct 249 CYKLTTVCPQVKPQTQGIAKDAWEIPRESLRLDVRLGQGCFGEVWMGTWNGT-----TKV 303 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + +E I++ L H+ ++ E+ + +V E++ GSL Sbjct 304 AIKTLKP--GTMSPEAFLEEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEFMGKGSLL 358 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI +GMA++ +YIHRDL A N+L+ ++ + KI DFGL Sbjct 359 DFLKEGDGKHLKLPQLVDMASQIADGMAFIERMNYIHRDLRAANILVADNLVCKIADFGL 418 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL+T Sbjct 419 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGR----- 471 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + E ++RG R+P P CP ++ +M+ CW+ E RPTFE Sbjct 472 ---------VPYPGMVNREVLEQVDRGYRMPCPQGCPESLHEMMRQCWKKEPDERPTFEY 522 Query 1165 LIPILKTVHEKYQGQ 1179 + L+ + Q Sbjct 523 IQSFLEDYFTATEPQ 537 >sp|Q04736|YES_MOUSE Tyrosine-protein kinase Yes OS=Mus musculus OX=10090 GN=Yes1 PE=1 SV=3 Length=541 Score = 303 bits (776), Expect = 1e-89, Method: Composition-based stats. Identities = 86/443 (19%), Positives = 154/443 (35%), Gaps = 70/443 (16%) Query 448 RDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 + G + + L + G++L+ S + L++ D ++ ++ Sbjct 154 EEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDW----DEVRGDNVKH 209 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + I + D F ++++L A C L C Sbjct 210 YKIRKLDNGGYYITTRAQFDTLQKLVKHYTEH---ADGLCHKLTTVCP------------ 254 Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 P+T L++ + ++ + LGQG V+ G Sbjct 255 ---TVKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT------------- 297 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 +V +K L P + AF + A +M ++ H L ++ V Sbjct 298 ------------TKVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLYAVVSE-EPIY 343 Query 685 MVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 +VTE++ G L +L+ G + + + +A Q+A ++Y+E N +H ++ NIL+ Sbjct 344 IVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILV- 402 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKW 798 G + K++D G+ E I W APE G + D W Sbjct 403 ------GENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG--RFTIKSDVW 454 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQR 856 FG E+ G P E +R +R+P P CP+ L L + C +P +R Sbjct 455 SFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDER 514 Query 857 PSFRTILRDLTRLQPHNLADVLT 879 P+F I L Sbjct 515 PTFEYIQSFLEDYFTATEPQYQP 537 Score = 288 bits (738), Expect = 2e-84, Method: Composition-based stats. Identities = 94/315 (30%), Positives = 145/315 (46%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + + + A D + L+ LG+G FG+V + ++ T V Sbjct 246 CHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT-----TKV 300 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL Sbjct 301 AIKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEFMSKGSLL 355 Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ + + KI DFGL Sbjct 356 DFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLICKIADFGL 415 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ EL+T Sbjct 416 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGR----- 468 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + E +ERG R+P P CP ++ LM CW+ + RPTFE Sbjct 469 ---------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEY 519 Query 1165 LIPILKTVHEKYQGQ 1179 + L+ + Q Sbjct 520 IQSFLEDYFTATEPQ 534 >sp|Q1JPZ3|SRC_DANRE Proto-oncogene tyrosine-protein kinase Src OS=Danio rerio OX=7955 GN=src PE=1 SV=2 Length=534 Score = 302 bits (774), Expect = 1e-89, Method: Composition-based stats. Identities = 97/465 (21%), Positives = 158/465 (34%), Gaps = 70/465 (15%) Query 426 LTADSSHYLCHEVAPPRLVMSIRDGIHGPLL---EPFVQAKLRPEDGLYLIHWSTSHPYR 482 LT S Y+ P + + G + + L G +L+ S + Sbjct 125 LTTGESGYIPSNYVAPSDSIQAEEWYFGKITRRDSERLLLNLENRRGTFLVRESETTKGA 184 Query 483 LILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGD 542 L+V D ++ L ++ + I + D F ++++L + A Sbjct 185 YCLSVLDY----DNVKGLNVKHYKIRKLDSGGFYITSRTQFSTLQQLVNHYRQH---ADG 237 Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTN 602 C SL C P T L++ + + + LGQG Sbjct 238 LCHSLTDVCP---------------VLKPPTQGLAR-DAWEIPRDSLRLDVKLGQGCFGE 281 Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662 V+ G RV +K L P AF + A +M Sbjct 282 VWMGTWNGT-------------------------TRVAIKTLKPGTMSP-EAFLQEAQVM 315 Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASA 721 ++ H L ++ V +VTEY+ G L +L+ + G + + + +A Q+AS Sbjct 316 KKLRHEKLVQLYAVVSE-EPIYIVTEYMGQGSLLDFLKGDMGKMLRLPQLVDMASQIASG 374 Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RI 776 ++Y+E N VH ++ NIL+ G + K++D G+ E I Sbjct 375 MAYVERMNYVHRDLRAANILV-------GDNLVCKVADFGLARLIEDNEYTARQGAKFPI 427 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836 W APE G + D W FG L E+ G P E +R +R+P P Sbjct 428 KWTAPEAALYG--RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCP 485 Query 837 --SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 L L C EP +RP+F + L Sbjct 486 AECPDSLHELMLTCWRKEPEERPTFEYLQGFLEDYFTSTEPQYQP 530 Score = 283 bits (723), Expect = 2e-82, Method: Composition-based stats. Identities = 97/315 (31%), Positives = 147/315 (47%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 ++ VL A D + L+ LG+G FG+V + ++ T V Sbjct 239 CHSLTDVCPVLKPPTQGLARDAWEIPRDSLRLDVKLGQGCFGEVWMGTWNGTTR-----V 293 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL Sbjct 294 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYMGQGSLL 348 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ ++ + K+ DFGL Sbjct 349 DFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGL 408 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 409 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 461 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW E RPTFE Sbjct 462 ---------VPYPGMVNREVLDQVERGYRMPCPAECPDSLHELMLTCWRKEPEERPTFEY 512 Query 1165 LIPILKTVHEKYQGQ 1179 L L+ + Q Sbjct 513 LQGFLEDYFTSTEPQ 527 >sp|P13115|SRC1_XENLA Tyrosine-protein kinase Src-1 OS=Xenopus laevis OX=8355 GN=src-a PE=2 SV=4 Length=532 Score = 302 bits (773), Expect = 2e-89, Method: Composition-based stats. Identities = 101/453 (22%), Positives = 162/453 (36%), Gaps = 71/453 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L+V+ Sbjct 136 VAPSDSIQA-EEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDY---- 190 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + L ++ + I + D F S+++L A A C L C Sbjct 191 DANRGLNVKHYKIRKLDSGGFYITSRTQFISLQQLVAYYSKH---ADGLCHRLTTVCP-- 245 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 A P+T LS+ + + + LGQG V+ G Sbjct 246 -------------TAKPQTQGLSR-DAWEIPRDSLRLELKLGQGCFGEVWMGTWNGT--- 288 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 RV +K L P AF + A +M ++ H L ++ Sbjct 289 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 325 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTEY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH Sbjct 326 AVVSE-EPIYIVTEYISKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHR 384 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 385 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 436 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 437 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPDCPESLHDLMF 495 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 QC +P +RP+F + L Sbjct 496 QCWRKDPEERPTFEYLQAFLEDYFTATEPQYQP 528 Score = 286 bits (732), Expect = 1e-83, Method: Composition-based stats. Identities = 93/315 (30%), Positives = 143/315 (45%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + + + D + L+ LG+G FG+V + ++ T V Sbjct 237 CHRLTTVCPTAKPQTQGLSRDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTR-----V 291 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V EY+ GSL Sbjct 292 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVTEYISKGSLL 346 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 347 DFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 406 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 407 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 459 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P CP ++ LM CW + RPTFE Sbjct 460 ---------VPYPGMVNREVLDQVERGYRMPCPPDCPESLHDLMFQCWRKDPEERPTFEY 510 Query 1165 LIPILKTVHEKYQGQ 1179 L L+ + Q Sbjct 511 LQAFLEDYFTATEPQ 525 >sp|Q6P6U0|FGR_RAT Tyrosine-protein kinase Fgr OS=Rattus norvegicus OX=10116 GN=Fgr PE=1 SV=1 Length=517 Score = 301 bits (770), Expect = 3e-89, Method: Composition-based stats. Identities = 92/456 (20%), Positives = 160/456 (35%), Gaps = 71/456 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + +L + G +LI S + L++ Q Sbjct 121 VAPVDSIQA-EEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQN- 178 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 + ++ + I + D F SV++L C+ L C+ Sbjct 179 ---RGDHIKHYKIRKLDMGGYYITTRAQFESVQDLVRHYMEVN---DGLCYLLTAPCM-- 230 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P+TL L++ +D+ I LG G +V+ G Sbjct 231 -------------VMKPQTLGLAK-DAWEIDRNSIALDRRLGTGCFGDVWLGTWNCS--- 273 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P AF E A +M + H L ++ Sbjct 274 ----------------------TKVAVKTLKPGTMSP-KAFLEEAQIMKLLRHDKLVQLY 310 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTE++ +G L +L+ +GH + + + +A Q+A ++Y+E N +H Sbjct 311 AVVSE-EPIYIVTEFMCYGSLLDFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHR 369 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIPWLAPECLPGGA 788 ++ NIL+ G K++D G+ + E I W APE G Sbjct 370 DLRAANILV-------GEHLICKIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFG- 421 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846 + D W FG L E+ G P + E + + +P P CP L + Sbjct 422 -RFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPVSLYEVME 480 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 Q +P +RP+F + L + Sbjct 481 QTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQPGDQ 516 Score = 271 bits (692), Expect = 2e-78, Method: Composition-based stats. Identities = 93/315 (30%), Positives = 141/315 (45%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 V+ A D + + R LG G FG V L ++ + V Sbjct 222 CYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRRLGTGCFGDVWLGTWNCS-----TKV 276 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 AVK LK G + +E I++ L H+ +++ E+ + +V E++ GSL Sbjct 277 AVKTLKP--GTMSPKAFLEEAQIMKLLRHDKLVQLYAVV---SEEPIYIVTEFMCYGSLL 331 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L H++ L L+ A Q+ EGMAY+ +YIHRDL A N+L+ + KI DFGL Sbjct 332 DFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLICKIADFGL 391 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y ++ P+ W APE +F SDVWSFG+ L EL+T Sbjct 392 ARLIVDDE--YNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGR----- 444 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + E +E G +P P CP +Y +M+ W + RPTFE Sbjct 445 ---------VPYPGMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEY 495 Query 1165 LIPILKTVHEKYQGQ 1179 L L+ + Q Sbjct 496 LQSFLEDYFTSTEPQ 510 >sp|F1LM93|YES_RAT Tyrosine-protein kinase Yes OS=Rattus norvegicus OX=10116 GN=Yes1 PE=1 SV=1 Length=541 Score = 301 bits (770), Expect = 6e-89, Method: Composition-based stats. Identities = 89/453 (20%), Positives = 159/453 (35%), Gaps = 71/453 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G++L+ S + L++ Sbjct 145 VAPADSIQA-EEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDW---- 199 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D ++ ++ + I + D F ++++L A C L C Sbjct 200 DEVRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEH---ADGLCHKLTTVCP-- 254 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P+T L++ + ++ + LGQG V+ G Sbjct 255 -------------TVKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 297 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P + AF + A +M ++ H L ++ Sbjct 298 ----------------------TKVAIKTLKPGTM-MPEAFLQEAQIMKKLRHDKLVPLY 334 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTE++ G L +L+ G + + + +A Q+A ++Y+E N +H Sbjct 335 AVVSE-EPIYIVTEFMSKGILLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHR 393 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 394 DLRAANILV-------GENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 445 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG E+ G P E +R +R+P P CP+ L L + Sbjct 446 -RFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMN 504 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 C +P +RP+F I L Sbjct 505 LCWKKDPDERPTFEYIQSFLEDYFTATEPQYQP 537 Score = 285 bits (729), Expect = 4e-83, Method: Composition-based stats. Identities = 93/315 (30%), Positives = 144/315 (46%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + + + A D + L+ LG+G FG+V + ++ T V Sbjct 246 CHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT-----TKV 300 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE I++ L H+ ++ E+ + +V E++ G L Sbjct 301 AIKTLKP--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEFMSKGILL 355 Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ + + KI DFGL Sbjct 356 DFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGL 415 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ EL+T Sbjct 416 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGR----- 468 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + E +ERG R+P P CP ++ LM CW+ + RPTFE Sbjct 469 ---------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEY 519 Query 1165 LIPILKTVHEKYQGQ 1179 + L+ + Q Sbjct 520 IQSFLEDYFTATEPQ 534 >sp|P14234|FGR_MOUSE Tyrosine-protein kinase Fgr OS=Mus musculus OX=10090 GN=Fgr PE=1 SV=2 Length=517 Score = 299 bits (766), Expect = 1e-88, Method: Composition-based stats. Identities = 89/456 (20%), Positives = 155/456 (34%), Gaps = 71/456 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + +L G +LI S + L++ Q Sbjct 121 VAPVDSIQA-EEWYFGKISRKDAERQLLSSGNPQGAFLIRESETTKGAYSLSIRDWDQN- 178 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 + ++ + I + D F S+++L C+ L C Sbjct 179 ---RGDHIKHYKIRKLDTGGYYITTRAQFDSIQDLVRHYMEVN---DGLCYLLTAPC--- 229 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P+TL L++ +D+ I LG G +V+ G Sbjct 230 ------------TTTKPQTLGLAK-DAWEIDRNSIALERRLGTGCFGDVWLGTWNCS--- 273 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P AF E A +M + H L ++ Sbjct 274 ----------------------TKVAVKTLKPGTMSP-KAFLEEAQIMKLLRHDKLVQLY 310 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTE++ +G L +L+ G + + + +A Q+A ++Y+E N +H Sbjct 311 AVVSE-EPIYIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQVAEGMAYMERMNYIHR 369 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIPWLAPECLPGGA 788 ++ NIL+ + K++D G+ E I W APE G Sbjct 370 DLRAANILVGEYLI-------CKIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFG- 421 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846 + D W FG L E+ G P + E + + +P P CP L + Sbjct 422 -RFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEVME 480 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 Q +P +RP+F + L + Sbjct 481 QAWRLDPEERPTFEYLQSFLEDYFTSTEPQYQPGDQ 516 Score = 268 bits (686), Expect = 1e-77, Method: Composition-based stats. Identities = 89/293 (30%), Positives = 136/293 (46%), Gaps = 29/293 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + + R LG G FG V L ++ + VAVK LK G + +E Sbjct 244 WEIDRNSIALERRLGTGCFGDVWLGTWNCS-----TKVAVKTLKP--GTMSPKAFLEEAQ 296 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQ 1006 I++ L H+ +++ E+ + +V E++ GSL D+L ++ L L+ A Q Sbjct 297 IMKLLRHDKLVQLYAVV---SEEPIYIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQ 353 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 + EGMAY+ +YIHRDL A N+L+ + KI DFGLA+ + + Y ++ P+ Sbjct 354 VAEGMAYMERMNYIHRDLRAANILVGEYLICKIADFGLARLIEDNE--YNPQQGTKFPIK 411 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE +F SDVWSFG+ L EL+T + M + E Sbjct 412 WTAPEAALFGRFTVKSDVWSFGILLTELITKGR--------------VPYPGMNNREVLE 457 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +E G +P P CP +Y +M+ W + RPTFE L L+ + Q Sbjct 458 QVEHGYHMPCPPGCPASLYEVMEQAWRLDPEERPTFEYLQSFLEDYFTSTEPQ 510 >sp|P10447|ABL_FSVHY Tyrosine-protein kinase transforming protein Abl OS=Feline sarcoma virus (strain Hardy-Zuckerman 2) OX=11776 GN=ABL PE=2 SV=1 Length=439 Score = 296 bits (758), Expect = 2e-88, Method: Composition-based stats. Identities = 95/428 (22%), Positives = 157/428 (37%), Gaps = 70/428 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 HGP+ + L +G +L+ S S P + +++ R+ Sbjct 72 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG---------RVYH 122 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + I + F ++ EL A +L Sbjct 123 YRINTASDGKLYVSPESRFNTLAELVHH---HSTVADGLITTLHYPAPK----------- 168 Query 565 RGARASPRTLNLSQ-LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 R P +S +++ +IT LG G VYEG + Sbjct 169 ---RNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYS----------- 214 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 L V +K L ++ F + A++M ++ H +L + GVC R P Sbjct 215 -------------LTVAVKTLKEDTMEV-EEFLKEAAVMKEIKHPNLVQLLGVCTREPPF 260 Query 684 IMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 ++TE++ +G L +LR R V + +A Q++SA+ YLE KN +H ++ RN L+ Sbjct 261 YIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV 320 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDK 797 G + +K++D G+ I W APE L N S D Sbjct 321 -------GENHLVKVADFGLSRLMTGDTYTAHAGTKFPIKWTAPESLA--YNKFSIKSDV 371 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855 W FG L EI G +P S+ ++ +R+ PE ++ L C + P+ Sbjct 372 WAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSD 431 Query 856 RPSFRTIL 863 RP+F I Sbjct 432 RPAFAEIH 439 Score = 280 bits (715), Expect = 1e-82, Method: Composition-based stats. Identities = 94/300 (31%), Positives = 143/300 (48%), Gaps = 27/300 (9%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 P + TV SP D + + LG G +G+V + + VA Sbjct 163 HYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSL----TVA 218 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 VK LK D + +E +++ + H ++++ G C E ++ E++ G+L D Sbjct 219 VKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLD 274 Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 YL R + LL A QI M YL +++IHRDLAARN L+ + LVK+ DFGL+ Sbjct 275 YLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLS 334 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + Y P+ W APE L KF SDVW+FGV L+E+ T+ S Sbjct 335 RLMT--GDTYTAHAGTKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMS----- 387 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + ++ ELLE+ R+ RP+ CP +VY LM+ CW+ S RP F + Sbjct 388 ---------PYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPAFAEI 438 >sp|P00526|SRC_RSVP Tyrosine-protein kinase transforming protein Src OS=Rous sarcoma virus subgroup C (strain Prague) OX=11888 GN=V-SRC PE=1 SV=3 Length=526 Score = 299 bits (765), Expect = 2e-88, Method: Composition-based stats. Identities = 95/437 (22%), Positives = 161/437 (37%), Gaps = 71/437 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L+V+ Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRKSETAKGAYCLSVSD----F 191 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + ++ + I + F S+++L A A C L C Sbjct 192 DNAKGPNVKHYKIYKLYSGGFYITSRTQFGSLQQLVAYYSKH---ADGLCHRLANVCP-- 246 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + P+T L++ + ++ + + LGQG V+ G Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEAKLGQGCFGEVWMGTWNDT--- 289 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 RV +K L P AF + A +M ++ H L ++ Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 326 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +V EY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH Sbjct 327 AVVSE-EPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 496 Query 847 QCLTYEPTQRPSFRTIL 863 QC +P +RP+F+ + Sbjct 497 QCWRKDPEERPTFKYLQ 513 Score = 283 bits (724), Expect = 1e-82, Method: Composition-based stats. Identities = 93/305 (30%), Positives = 143/305 (47%), Gaps = 29/305 (10%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + N+ A D + L+ LG+G FG+V + ++ T V Sbjct 238 CHRLANVCPTSKPQTQGLAKDAWEIPRESLRLEAKLGQGCFGEVWMGTWNDTTR-----V 292 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVIEYMSKGSLL 347 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ERG R+P P +CP ++ LM CW + RPTF+ Sbjct 461 ---------VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFKY 511 Query 1165 LIPIL 1169 L L Sbjct 512 LQAQL 516 >sp|P25020|SRC_RSVH1 Tyrosine-protein kinase transforming protein Src OS=Rous sarcoma virus (strain H-19) OX=11887 GN=V-SRC PE=1 SV=3 Length=526 Score = 298 bits (764), Expect = 3e-88, Method: Composition-based stats. Identities = 95/437 (22%), Positives = 161/437 (37%), Gaps = 71/437 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G +L+ S + L+V+ Sbjct 137 VAPSDSIQA-EEWYFGKITRRESERLLLNPENPRGTFLVRKSETAKGAYCLSVSD----F 191 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + ++ + I + F S+++L A A C L C Sbjct 192 DNAKGPNVKHYKICKLYSGGFYITSRTQFGSLQQLVAYYSKH---ADGLCHRLTNVCP-- 246 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + P+T L++ + ++ + + LGQG V+ G Sbjct 247 -------------TSKPQTQGLAK-DAWEIPRESLRLEAKLGQGCFGEVWMGTWNGT--- 289 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 RV +K L P AF + A +M ++ H L ++ Sbjct 290 ----------------------TRVAIKTLKPGTMSP-EAFLQEAQVMKKLRHEKLVQLY 326 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +V EY+ G L +L+ E G + + + +A Q+AS ++Y+E N VH Sbjct 327 AVVSE-EPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHR 385 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 386 DLRAANILV-------GENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 437 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG L E+ G P E +R +R+P P CP+ L L Sbjct 438 -RFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERAYRMPCPPECPESLHDLMC 496 Query 847 QCLTYEPTQRPSFRTIL 863 QC +P +RP+F+ + Sbjct 497 QCWRKDPEERPTFKYLQ 513 Score = 282 bits (722), Expect = 2e-82, Method: Composition-based stats. Identities = 92/305 (30%), Positives = 142/305 (47%), Gaps = 29/305 (10%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + N+ A D + L+ LG+G FG+V + ++ T V Sbjct 238 CHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEAKLGQGCFGEVWMGTWNGTTR-----V 292 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE +++ L HE +++ E+ + +V+EY+ GSL Sbjct 293 AIKTLKP--GTMSPEAFLQEAQVMKKLRHEKLVQLYAVV---SEEPIYIVIEYMSKGSLL 347 Query 988 DYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI GMAY+ +Y+HRDL A N+L+ + + K+ DFGL Sbjct 348 DFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGL 407 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ L EL T Sbjct 408 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR----- 460 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + + +ER R+P P +CP ++ LM CW + RPTF+ Sbjct 461 ---------VPYPGMVNREVLDQVERAYRMPCPPECPESLHDLMCQCWRKDPEERPTFKY 511 Query 1165 LIPIL 1169 L L Sbjct 512 LQAQL 516 >sp|P16591|FER_HUMAN Tyrosine-protein kinase Fer OS=Homo sapiens OX=9606 GN=FER PE=1 SV=2 Length=822 Score = 306 bits (785), Expect = 4e-88, Method: Composition-based stats. Identities = 91/433 (21%), Positives = 178/433 (41%), Gaps = 80/433 (18%) Query 447 IRDGIHGPLLEPFVQAK-LRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKF 505 +D HG + P ++A+ L + G +L+ S P +L+V DG + R F Sbjct 457 EQDWYHGAI--PRIEAQELLKKQGDFLVRESHGKPGEYVLSVY-----SDGQR----RHF 505 Query 506 PIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMR 565 I+ D + EG G F ++ +L D ++ ++ + S ++++ Sbjct 506 IIQYVDNMYRFEGTG--FSNIPQLI-----------DHHYTTKQVITKK----SGVVLLN 548 Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 + + + +++ LG+G VY+G L+ Sbjct 549 P---------IPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKD--------------- 584 Query 626 PLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 + V +K ++ + F + A ++ Q H ++ + GVC + Sbjct 585 ----------KTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVY 634 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 ++ E V G +LRR++ + + + + A+ + YLE+KN +H ++ RN L+ Sbjct 635 IIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLESKNCIHRDLAARNCLV-- 692 Query 745 LGLAEGTSPFIKLSDPGVGL---GALSREERVERIP--WLAPECLPGGANSLSTAMDKWG 799 G + +K+SD G+ G + +++IP W APE L G S+ D W Sbjct 693 -----GENNVLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYG--RYSSESDVWS 745 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857 FG L E G P + + +R +R+ P+ ++ + +C Y+P RP Sbjct 746 FGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRP 805 Query 858 SFRTILRDLTRLQ 870 F + ++LT ++ Sbjct 806 KFSELQKELTIIK 818 Score = 274 bits (700), Expect = 1e-76, Method: Composition-based stats. Identities = 91/317 (29%), Positives = 138/317 (44%), Gaps = 25/317 (8%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 I T Q + + P + + LG+G+FG+V Sbjct 528 IDHHYTTKQVITKKSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLK---- 583 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VAVK K D + + + QE IL+ H +I+K G C + + + ++ME V Sbjct 584 -DKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQR--QPVYIIMELV 640 Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 G +L R + L QL+ F+ GM YL +++ IHRDLAARN L+ + ++KI Sbjct 641 SGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKI 700 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFG+++ E Y P+ W APE L ++ SDVWSFG+ L+E + Sbjct 701 SDFGMSRQ--EDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFS--- 755 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L MT + E +ERG R+ P CP ++ +M CW+ + R Sbjct 756 -----------LGVCPYPGMTNQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENR 804 Query 1160 PTFENLIPILKTVHEKY 1176 P F L L + K Sbjct 805 PKFSELQKELTIIKRKL 821 >sp|Q28923|YES_CANLF Tyrosine-protein kinase Yes OS=Canis lupus familiaris OX=9615 GN=YES1 PE=1 SV=3 Length=539 Score = 298 bits (763), Expect = 6e-88, Method: Composition-based stats. Identities = 88/453 (19%), Positives = 158/453 (35%), Gaps = 71/453 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + L + G++L+ S + L++ Sbjct 143 VAPADSIAA-EEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDW---- 197 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D ++ ++ + I + D F ++++L A C L C Sbjct 198 DEIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKH---STEHADGLCHKLTTVCP-- 252 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P+T L++ + ++ + LGQG V+ G Sbjct 253 -------------TVKPQTQGLAK-DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT--- 295 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L + AF + A +M ++ H L ++ Sbjct 296 ----------------------TKVAIKTLKLGTM-MPEAFLQEAQIMKKLRHDKLVPLY 332 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTE++ G L +L+ G + + + +A Q+A ++Y+E N +H Sbjct 333 AVVSE-EPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHR 391 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGA 788 ++ NIL+ G + K++D G+ E I W APE G Sbjct 392 DLRAANILV-------GENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG- 443 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTS 846 + D W FG E+ G P E +R +R+P P CP+ L L + Sbjct 444 -RFTIKSDVWSFGILQTELTTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMN 502 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 C +P +RP+F I L Sbjct 503 LCWKKDPDERPTFEYIQSFLEDYFTAAEPQYQP 535 Score = 287 bits (734), Expect = 7e-84, Method: Composition-based stats. Identities = 94/315 (30%), Positives = 144/315 (46%), Gaps = 29/315 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 + + + A D + L+ LG+G FG+V + ++ T V Sbjct 244 CHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGT-----TKV 298 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK G + QE I++ L H+ ++ E+ + +V E++ GSL Sbjct 299 AIKTLKL--GTMMPEAFLQEAQIMKKLRHDKLVPLYAVV---SEEPIYIVTEFMSKGSLL 353 Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 D+L + L QL+ A QI +GMAY+ +YIHRDL A N+L+ + + KI DFGL Sbjct 354 DFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGL 413 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + + Y R+ P+ W APE +F SDVWSFG+ EL T Sbjct 414 ARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELTTKGR----- 466 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + M + E +ERG R+P P CP ++ LM CW+ + RPTFE Sbjct 467 ---------VPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEY 517 Query 1165 LIPILKTVHEKYQGQ 1179 + L+ + Q Sbjct 518 IQSFLEDYFTAAEPQ 532 >sp|O13148|EPA4A_DANRE Ephrin type-A receptor 4a (Fragment) OS=Danio rerio OX=7955 GN=epha4a PE=2 SV=1 Length=292 Score = 288 bits (737), Expect = 1e-87, Method: Composition-based stats. Identities = 85/282 (30%), Positives = 143/282 (51%), Gaps = 30/282 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG+V G E+ VA+K LKA + R + E I+ H +II+ Sbjct 1 IGIGEFGEVCSGRLKM--PGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIR 58 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHY 1019 +G K + ++ EY+ GSL +L ++ + QL+ + I GM YL Y Sbjct 59 LEGVVTKC--KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGILRGIASGMKYLSDMSY 116 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE-YYRVREDGDS--------PVFWYAP 1070 +HRDLAARN+L++++ + K+ DFG+++ + E + Y RE + P+ W AP Sbjct 117 VHRDLAARNILVNSNLVCKVSDFGMSRVLEEDPDAAYTTREITGTYQSQGGKIPIRWTAP 176 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E + KF ASDVWS+G+ ++E++++ + M+ + + +E Sbjct 177 EAITYRKFTSASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVIKAIEE 222 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 G RLP P CP ++ LM +CW+ E + RP F ++ +L + Sbjct 223 GYRLPPPMDCPVSLHQLMLDCWQKERAERPKFSQIVNMLDKL 264 Score = 266 bits (680), Expect = 1e-79, Method: Composition-based stats. Identities = 76/298 (26%), Positives = 124/298 (42%), Gaps = 49/298 (16%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL- 653 +G G V GRL++ G +E+ V +K L + D Sbjct 1 IGIGEFGEVCSGRLKMPGK---------------------REICVAIKTLKAGYTDKQRR 39 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 F AS+M Q H ++ + GV + +++TEY+E+G LD +LR+ G + + Sbjct 40 DFLSEASIMGQFDHPNIIRLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVG 99 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-------GA 766 + + +AS + YL + + VH ++ RNIL+ ++ K+SD G+ A Sbjct 100 ILRGIASGMKYLSDMSYVHRDLAARNILVN-------SNLVCKVSDFGMSRVLEEDPDAA 152 Query 767 LSREERVER---------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + E I W APE + ++A D W +G + E+ GE P Sbjct 153 YTTREITGTYQSQGGKIPIRWTAPEAIT--YRKFTSASDVWSYGIVMWEVMSYGERPYWD 210 Query 818 RSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 S + + +RLP P CP L L C E +RP F I+ L +L + Sbjct 211 MSNQDVIKAIEEGYRLPPPMDCPVSLHQLMLDCWQKERAERPKFSQIVNMLDKLIRNP 268 >sp|G5EE56|SRC1_CAEEL Tyrosine protein-kinase src-1 OS=Caenorhabditis elegans OX=6239 GN=src-1 PE=1 SV=1 Length=533 Score = 297 bits (760), Expect = 1e-87, Method: Composition-based stats. Identities = 92/457 (20%), Positives = 166/457 (36%), Gaps = 66/457 (14%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAP 494 VA + + S + G + + + G +LI + LT+ Sbjct 127 VAKQQTIES-EEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQR 185 Query 495 DG--MQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552 +G ++ ++++ D + + R+F S++EL C L Sbjct 186 NGGTVKHYKIKRL---DHDQGYFIT-TRRTFRSLQELVRYYSD---VPDGLCCQLTFPAP 238 Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 R A P L+ + + ++ LG G V+ G+ R Sbjct 239 ------------RLAPTRP-DLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGI- 284 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672 + V +K + P AF + A +M Q H +L Sbjct 285 ------------------------VEVAIKTMKPGTMSP-EAFLQEAQIMKQCDHPNLVK 319 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVH 732 ++ VC R ++TEY+ +G L +LR + + + + +A Q+A+ + YLE + LVH Sbjct 320 LYAVCTREEPFYIITEYMINGSLLQYLRTDGSTLGIQALVDMAAQIANGMMYLEERKLVH 379 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL------SREERVERIPWLAPECLPG 786 ++ RN+L+ G P +K++D G+ + +R I W APE Sbjct 380 RDLAARNVLV---GDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATC 436 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ--LAT 843 G + + D W +G L EI G+ P E + +R+P P CP+ Sbjct 437 G--NFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEE 494 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880 + +C P +RP+F T+ + Sbjct 495 VLLKCWDKTPDRRPTFDTLYHFFDDYFVSTQPNYAPP 531 Score = 270 bits (689), Expect = 9e-78, Method: Composition-based stats. Identities = 90/314 (29%), Positives = 136/314 (43%), Gaps = 31/314 (10%) Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 P + + L R LG+G+FG+V + Sbjct 230 CCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGI----- 284 Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 VA+K +K G + QE I++ H +++K C E+ ++ EY+ G Sbjct 285 VEVAIKTMKP--GTMSPEAFLQEAQIMKQCDHPNLVKLYAVCTR--EEPFYIITEYMING 340 Query 985 SLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND----RLVK 1038 SL YL ++G+ L+ A QI GM YL + +HRDLAARNVL+ + +VK Sbjct 341 SLLQYLRTDGSTLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVK 400 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 + DFGLA+ + E + Y R P+ W APE F SDVWS+G+ LYE++T Sbjct 401 VADFGLARKLME-EDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKG 459 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY-HLMKNCWETEAS 1157 + M + E +E G R+P P CP ++Y ++ CW+ Sbjct 460 Q--------------VPYPGMHNREVVEQVELGYRMPMPRGCPEQIYEEVLLKCWDKTPD 505 Query 1158 FRPTFENLIPILKT 1171 RPTF+ L Sbjct 506 RRPTFDTLYHFFDD 519 >sp|P00521|ABL_MLVAB Tyrosine-protein kinase transforming protein Abl OS=Abelson murine leukemia virus OX=11788 GN=ABL PE=3 SV=1 Length=746 Score = 303 bits (775), Expect = 2e-87, Method: Composition-based stats. Identities = 96/436 (22%), Positives = 159/436 (36%), Gaps = 70/436 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 HGP+ + L +G +L+ S S P + +++ R+ Sbjct 9 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG---------RVYH 59 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + I + F ++ EL A +L Sbjct 60 YRINTASDGKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPK----------- 105 Query 565 RGARASPRTLNLSQ-LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 R P +S +++ +IT LG G VYEG + Sbjct 106 ---RNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYS----------- 151 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 L V +K L ++ F + A++M ++ H +L + GVC R P Sbjct 152 -------------LTVAVKTLKEDTMEV-EEFLKEAAVMKEIKHPNLVQLLGVCTREPPF 197 Query 684 IMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 ++TE++ +G L +LR R V + +A Q++SA+ YLE KN +H ++ RN L+ Sbjct 198 YIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV 257 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDK 797 G + +K++D G+ I W APE L N S D Sbjct 258 -------GENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLA--YNKFSIKSDV 308 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855 W FG L EI G +P S+ ++ +R+ PE ++ L C + P+ Sbjct 309 WAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSD 368 Query 856 RPSFRTILRDLTRLQP 871 RPSF I + + Sbjct 369 RPSFAEIHQAFETMFQ 384 Score = 295 bits (755), Expect = 1e-84, Method: Composition-based stats. Identities = 94/310 (30%), Positives = 149/310 (48%), Gaps = 27/310 (9%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 P + T+ SP D + + LG G +G+V + + VA Sbjct 100 HYPAPKRNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSL----TVA 155 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 VK LK D + +E +++ + H ++++ G C E ++ E++ G+L D Sbjct 156 VKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLD 211 Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 YL R + LL A QI M YL +++IHRDLAARN L+ + LVK+ DFGL+ Sbjct 212 YLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLS 271 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + Y P+ W APE L KF SDVW+FGV L+E+ T+ S Sbjct 272 RLMT--GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMS----- 324 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + ++ ELLE+ R+ RP+ CP +VY LM+ CW+ S RP+F + Sbjct 325 ---------PYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 375 Query 1166 IPILKTVHEK 1175 +T+ ++ Sbjct 376 HQAFETMFQE 385 >sp|P09769|FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo sapiens OX=9606 GN=FGR PE=1 SV=2 Length=529 Score = 294 bits (752), Expect = 2e-86, Method: Composition-based stats. Identities = 94/456 (21%), Positives = 156/456 (34%), Gaps = 71/456 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + +L G +LI S + L++ Sbjct 133 VAPVDSIQA-EEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDW---- 187 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + ++ + I + D F SV+EL C Sbjct 188 DQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVN---DGLC---------- 234 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 NL+I P+TL L++ + + IT LG G +V+ G Sbjct 235 -----NLLIAPCTIMKPQTLGLAK-DAWEISRSSITLERRLGTGCFGDVWLGTWNGS--- 285 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P AF E A +M + H L ++ Sbjct 286 ----------------------TKVAVKTLKPGTMSP-KAFLEEAQVMKLLRHDKLVQLY 322 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTE++ HG L +L+ G + + + +A Q+A ++Y+E N +H Sbjct 323 AVVSE-EPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHR 381 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGGA 788 ++ NIL+ G K++D G+ E I W APE G Sbjct 382 DLRAANILV-------GERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFG- 433 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846 + D W FG L E+ G P + E ++ + +P P CP L Sbjct 434 -RFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAME 492 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 Q +P +RP+F + L + Sbjct 493 QTWRLDPEERPTFEYLQSFLEDYFTSAEPQYQPGDQ 528 Score = 270 bits (689), Expect = 8e-78, Method: Composition-based stats. Identities = 92/309 (30%), Positives = 138/309 (45%), Gaps = 29/309 (9%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933 ++ A D + + R LG G FG V L ++ + VAVK LK Sbjct 240 PCTIMKPQTLGLAKDAWEISRSSITLERRLGTGCFGDVWLGTWNGS-----TKVAVKTLK 294 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR- 992 G + +E +++ L H+ +++ E+ + +V E++ GSL D+L Sbjct 295 P--GTMSPKAFLEEAQVMKLLRHDKLVQLYAVV---SEEPIYIVTEFMCHGSLLDFLKNP 349 Query 993 --HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 + L QL+ A Q+ EGMAY+ +YIHRDL A N+L+ KI DFGLA+ + + Sbjct 350 EGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARLIKD 409 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 Y + P+ W APE +F SDVWSFG+ L EL+T Sbjct 410 DE--YNPCQGSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGR----------- 456 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 I M + E +E+G +P P CP +Y M+ W + RPTFE L L+ Sbjct 457 ---IPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYLQSFLE 513 Query 1171 TVHEKYQGQ 1179 + Q Sbjct 514 DYFTSAEPQ 522 >sp|P54755|EPHA5_CHICK Ephrin type-A receptor 5 OS=Gallus gallus OX=9031 GN=EPHA5 PE=2 SV=1 Length=1013 Score = 305 bits (781), Expect = 4e-86, Method: Composition-based stats. Identities = 88/337 (26%), Positives = 154/337 (46%), Gaps = 24/337 (7%) Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR-----YL 897 +L +C + Q P + ++ + + + + + + Sbjct 592 SLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCI 651 Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 R +G G FG+V VA+K LK + R + E I+ H Sbjct 652 TIERVIGAGEFGEVCSGRLKLQGKREF-PVAIKTLKVGYTEKQRRDFLGEASIMGQFDHP 710 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015 +II +G K + +V EY+ GSL +L ++ + QL+ + I GM YL Sbjct 711 NIIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIASGMKYLS 768 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W APE + Sbjct 769 DMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAF 828 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF ASDVWS+G+ ++E++++ + +MT + + +E G RLP Sbjct 829 RKFTSASDVWSYGIVMWEVMSYGER--------------PYWEMTNQDVIKAVEEGYRLP 874 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P CP +Y LM +CW+ + + RP F+ ++ +L + Sbjct 875 SPMDCPAALYQLMLDCWQKDRNSRPKFDEIVSMLDKL 911 Score = 274 bits (701), Expect = 1e-75, Method: Composition-based stats. Identities = 73/302 (24%), Positives = 123/302 (41%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 ++ IT +G G V GRL+++G +E V + Sbjct 644 KEIEASCITIERVIGAGEFGEVCSGRLKLQGK---------------------REFPVAI 682 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +L+ Sbjct 683 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLK 742 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +AS + YL + VH ++ RNIL+ ++ K+SD Sbjct 743 KNDGQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 795 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E I W APE + ++A D W +G + E+ GE Sbjct 796 GLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--FRKFTSASDVWSYGIVMWEVMSYGER 853 Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P + + + +RLP CP L L C + RP F I+ L +L Sbjct 854 PYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVSMLDKLIR 913 Query 872 HN 873 + Sbjct 914 NP 915 >sp|Q60629|EPHA5_MOUSE Ephrin type-A receptor 5 OS=Mus musculus OX=10090 GN=Epha5 PE=1 SV=2 Length=876 Score = 302 bits (774), Expect = 4e-86, Method: Composition-based stats. Identities = 87/337 (26%), Positives = 154/337 (46%), Gaps = 24/337 (7%) Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR-----YL 897 +L +C + Q P + ++ + + + + + + Sbjct 455 SLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCI 514 Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 R +G G FG+V VA+K LK + R + E I+ H Sbjct 515 TIERVIGAGEFGEVCSGRLKLPGKRE-LPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHP 573 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015 +II +G K + +V EY+ GSL +L ++ + QL+ + I GM YL Sbjct 574 NIIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLS 631 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W APE + Sbjct 632 DMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAF 691 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF +SDVWS+G+ ++E++++ + +MT + + +E G RLP Sbjct 692 RKFTSSSDVWSYGIVMWEVVSYGER--------------PYWEMTNQDVIKAVEEGYRLP 737 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P CP +Y LM +CW+ + + RP F+ ++ +L + Sbjct 738 SPMDCPAALYQLMLDCWQKDRNSRPKFDEIVNMLDKL 774 Score = 273 bits (698), Expect = 6e-76, Method: Composition-based stats. Identities = 72/302 (24%), Positives = 123/302 (41%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 ++ IT +G G V GRL++ G +EL V + Sbjct 507 KEIEASCITIERVIGAGEFGEVCSGRLKLPGK---------------------RELPVAI 545 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +L+ Sbjct 546 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLK 605 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL + VH ++ RNIL+ ++ K+SD Sbjct 606 KNDGQFTVIQLVGMLRGIAAGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 658 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E I W APE + +++ D W +G + E+ GE Sbjct 659 GLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--FRKFTSSSDVWSYGIVMWEVVSYGER 716 Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P + + + +RLP CP L L C + RP F I+ L +L Sbjct 717 PYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVNMLDKLIR 776 Query 872 HN 873 + Sbjct 777 NP 778 >sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens OX=9606 GN=LYN PE=1 SV=3 Length=512 Score = 292 bits (747), Expect = 5e-86, Method: Composition-based stats. Identities = 85/447 (19%), Positives = 152/447 (34%), Gaps = 70/447 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502 + + + +L G +LI S + L+V + + Sbjct 125 ETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDP----VHGDVI 180 Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562 + + I D +FP + ++ Q A C L + C+ Sbjct 181 KHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQ---ADGLCRRLEKACI---------- 227 Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 SP+ + ++ I + LG G V+ G Sbjct 228 -------SPKPQKPWDKDAWEIPRESIKLVKRLGAGQFGEVWMG---------------- 264 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 +V +K L P + AF E A+LM + H L ++ V R Sbjct 265 ---------YYNNSTKVAVKTLKPGTMSVQ-AFLEEANLMKTLQHDKLVRLYAVVTREEP 314 Query 683 NIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 ++TEY+ G L +L+ + G V + + + Q+A ++Y+E KN +H ++ N+L Sbjct 315 IYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVL 374 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMD 796 ++ S K++D G+ E I W APE + G + D Sbjct 375 VSE-------SLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGC--FTIKSD 425 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP--EPSCPQLATLTSQCLTYEPT 854 W FG L EI G+ P R+ ++ + +R+P E +L + C + Sbjct 426 VWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKMCWKEKAE 485 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVN 881 +RP+F + L Sbjct 486 ERPTFDYLQSVLDDFYTATEGQYQQQP 512 Score = 279 bits (714), Expect = 2e-81, Method: Composition-based stats. Identities = 101/293 (34%), Positives = 153/293 (52%), Gaps = 28/293 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + +K ++ LG G FG+V + Y N+ T VAVK LK G + +E + Sbjct 240 WEIPRESIKLVKRLGAGQFGEVWMGYY---NNST--KVAVKTLKP--GTMSVQAFLEEAN 292 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQ 1006 +++TL H+ +++ E+ + ++ EY+ GSL D+L G L +L+ F+ Q Sbjct 293 LMKTLQHDKLVRLYAVVTR--EEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQ 350 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I EGMAY+ ++YIHRDL A NVL+ + KI DFGLA+ + + Y RE P+ Sbjct 351 IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIK 408 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE + F SDVWSFG+ LYE++T+ I T + Sbjct 409 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGK--------------IPYPGRTNADVMT 454 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +G R+PR + CP E+Y +MK CW+ +A RPTF+ L +L + +GQ Sbjct 455 ALSQGYRMPRVENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQ 507 >sp|P25911|LYN_MOUSE Tyrosine-protein kinase Lyn OS=Mus musculus OX=10090 GN=Lyn PE=1 SV=4 Length=512 Score = 292 bits (747), Expect = 5e-86, Method: Composition-based stats. Identities = 84/447 (19%), Positives = 153/447 (34%), Gaps = 70/447 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502 + + + +L G +LI S + L+V M + Sbjct 125 ETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDP----MHGDVI 180 Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562 + + I D +FP + ++ Q + C L + C+ Sbjct 181 KHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQ---SDGLCRRLEKACI---------- 227 Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 SP+ + ++ I + LG G V+ G Sbjct 228 -------SPKPQKPWDKDAWEIPRESIKLVKKLGAGQFGEVWMG---------------- 264 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 +V +K L P + AF E A+LM + H L ++ V + Sbjct 265 ---------YYNNSTKVAVKTLKPGTMSVQ-AFLEEANLMKTLQHDKLVRLYAVVTKEEP 314 Query 683 NIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 ++TE++ G L +L+ + G V + + + Q+A ++Y+E KN +H ++ N+L Sbjct 315 IYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVL 374 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMD 796 ++ S K++D G+ E I W APE + G + D Sbjct 375 VSE-------SLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGC--FTIKSD 425 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPT 854 W FG L EI G+ P R+ ++ + +R+P +CP L + C + Sbjct 426 VWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPRMENCPDELYDIMKMCWKEKAE 485 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVN 881 +RP+F + L Sbjct 486 ERPTFDYLQSVLDDFYTATEGQYQQQP 512 Score = 278 bits (711), Expect = 5e-81, Method: Composition-based stats. Identities = 100/293 (34%), Positives = 153/293 (52%), Gaps = 28/293 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + +K ++ LG G FG+V + Y N+ T VAVK LK G + +E + Sbjct 240 WEIPRESIKLVKKLGAGQFGEVWMGYY---NNST--KVAVKTLKP--GTMSVQAFLEEAN 292 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQ 1006 +++TL H+ +++ E+ + ++ E++ GSL D+L G L +L+ F+ Q Sbjct 293 LMKTLQHDKLVRLYAVVTK--EEPIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQ 350 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I EGMAY+ ++YIHRDL A NVL+ + KI DFGLA+ + + Y RE P+ Sbjct 351 IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIK 408 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE + F SDVWSFG+ LYE++T+ I T + Sbjct 409 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGK--------------IPYPGRTNADVMS 454 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +G R+PR + CP E+Y +MK CW+ +A RPTF+ L +L + +GQ Sbjct 455 ALSQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQ 507 >sp|P00543|FES_FSVST Tyrosine-protein kinase transforming protein Fes OS=Feline sarcoma virus (strain Snyder-Theilen) OX=11780 GN=V-FES PE=3 SV=1 Length=477 Score = 290 bits (743), Expect = 6e-86, Method: Composition-based stats. Identities = 112/451 (25%), Positives = 176/451 (39%), Gaps = 85/451 (19%) Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQ-AKLRPEDGLYLIHWSTSHPYRLILTVAQRSQ 492 L EV P + HG L P + A+L G +L+ S +L+V Sbjct 102 LVPEVQKPL---HEQLWYHGAL--PRAEVAELLTHSGDFLVRESQGKQ-EYVLSV----- 150 Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552 DG R F I+ D + EG G F S+ L L LR+ Sbjct 151 LWDGQP----RHFIIQSADNLYRPEGDG--FASIPLLVDHL----LRS------------ 188 Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 QP + I++ A + ++ +++ +G+G V+ GRLR + Sbjct 189 QQPLTKKSGIVLNRAVPKDK---------WVLNHEDLVLGEQIGRGNFGEVFSGRLRADN 239 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLA 671 V +K + DI F + A ++ Q SH ++ Sbjct 240 ------------------------TLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIV 275 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 + GVC + +V E V+ G +LR E + M + + A+ + YLE+K + Sbjct 276 RLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCI 335 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPECLP 785 H ++ RN L+ + +K+SD G+ A S R+ + W APE L Sbjct 336 HRDLAARNCLVTEKNV-------LKISDFGMSREEADGVYAASGGLRLVPVKWTAPEALN 388 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LAT 843 G S+ D W FG L E G +P + S + F ++ RLP P CP + Sbjct 389 YG--RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFR 446 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 L QC YEP QRPSF ++L ++ + Sbjct 447 LMEQCWAYEPGQRPSFSAFYQELQSIRKRHR 477 Score = 270 bits (689), Expect = 2e-78, Method: Composition-based stats. Identities = 87/294 (30%), Positives = 138/294 (47%), Gaps = 23/294 (8%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 D V + L +G G+FG+V N +VAVK+ + P ++ + Sbjct 205 PKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADN----TLVAVKSCRETLPPDIKAKFL 260 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLF 1003 QE IL+ H +I++ G C + + + +VME V G +L + + LL Sbjct 261 QEAKILKQYSHPNIVRLIGVCTQK--QPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQM 318 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 GM YL ++ IHRDLAARN L+ ++KI DFG+++ +G Y Sbjct 319 VGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGV-YAASGGLRLV 377 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 PV W APE L ++ SDVWSFG+ L+E + L ++ + Sbjct 378 PVKWTAPEALNYGRYSSESDVWSFGILLWETFS--------------LGASPYPNLSNQQ 423 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 E +E+G RLP P+ CP V+ LM+ CW E RP+F L+++ ++++ Sbjct 424 TREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAFYQELQSIRKRHR 477 >sp|Q07014|LYN_RAT Tyrosine-protein kinase Lyn OS=Rattus norvegicus OX=10116 GN=Lyn PE=1 SV=3 Length=512 Score = 291 bits (746), Expect = 7e-86, Method: Composition-based stats. Identities = 85/447 (19%), Positives = 152/447 (34%), Gaps = 70/447 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502 + + + +L G +LI S + L+V M + Sbjct 125 ETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDP----MHGDVI 180 Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562 + + I D +FP + ++ Q + C L + C+ Sbjct 181 KHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQ---SDGLCRRLEKACI---------- 227 Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 SP+ + ++ I + LG G V+ G Sbjct 228 -------SPKPQKPWDKDAWEIPRESIKLVKKLGAGQFGEVWMG---------------- 264 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 +V +K L P A AF E A+LM + H L ++ V + Sbjct 265 ---------YYNNSTKVAVKTLKPGTMS-AQAFLEEANLMKTLQHDKLVRLYAVVTKEEP 314 Query 683 NIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 ++TE++ G L +L+ + G V + + + Q+A ++Y+E KN +H ++ N+L Sbjct 315 IYIITEFMAKGSLLDFLKSDEGSKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVL 374 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMD 796 ++ S K++D G+ E I W APE + G + D Sbjct 375 VSE-------SLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGC--FTIKSD 425 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPT 854 W FG L EI G+ P R+ ++ + +R+P +CP L + C Sbjct 426 VWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRMENCPDELYDIMKMCWKESAE 485 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVN 881 +RP+F + L Sbjct 486 ERPTFDYLQSVLDDFYTATEGQYQQQP 512 Score = 277 bits (708), Expect = 1e-80, Method: Composition-based stats. Identities = 99/293 (34%), Positives = 151/293 (52%), Gaps = 28/293 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + +K ++ LG G FG+V + Y N+ T VAVK LK G + +E + Sbjct 240 WEIPRESIKLVKKLGAGQFGEVWMGYY---NNST--KVAVKTLKP--GTMSAQAFLEEAN 292 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQ 1006 +++TL H+ +++ E+ + ++ E++ GSL D+L L +L+ F+ Q Sbjct 293 LMKTLQHDKLVRLYAVVTK--EEPIYIITEFMAKGSLLDFLKSDEGSKVLLPKLIDFSAQ 350 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I EGMAY+ ++YIHRDL A NVL+ + KI DFGLA+ + + Y RE P+ Sbjct 351 IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIK 408 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE + F SDVWSFG+ LYE++T+ I T + Sbjct 409 WTAPEAINFGCFTIKSDVWSFGILLYEIVTYGK--------------IPYPGRTNADVMT 454 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +G R+PR + CP E+Y +MK CW+ A RPTF+ L +L + +GQ Sbjct 455 ALSQGYRMPRMENCPDELYDIMKMCWKESAEERPTFDYLQSVLDDFYTATEGQ 507 >sp|Q95KR7|LCK_SAISC Proto-oncogene tyrosine-protein kinase LCK OS=Saimiri sciureus OX=9521 GN=LCK PE=1 SV=3 Length=509 Score = 291 bits (744), Expect = 1e-85, Method: Composition-based stats. Identities = 103/293 (35%), Positives = 150/293 (51%), Gaps = 29/293 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + LK + LG G FG+V + Y N+ T VAVK+LK G + E + Sbjct 238 WEVPRETLKLVERLGAGQFGEVWMGYY---NEHT--KVAVKSLKQ--GSMSPDAFLAEAN 290 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQ 1006 +++ L H+ +++ E+ + ++ EY+ GSL D+L S + + +LL A Q Sbjct 291 LMKQLQHKRLVRLYAVV---TEEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQ 347 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I EGMA+L ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ Sbjct 348 IVEGMAFLEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIK 405 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE + F SDVWSFG+ + E++TH I MT + + Sbjct 406 WTAPEAINYGTFTIKSDVWSFGILMTEIVTHGR--------------IPYPGMTNPEVIQ 451 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 LERG R+PRPD CP E+Y LM CW RPTF+ L +L+ +GQ Sbjct 452 NLERGYRMPRPDNCPEELYKLMMQCWRERPDDRPTFDYLRSVLEDFFTATEGQ 504 Score = 288 bits (737), Expect = 1e-84, Method: Composition-based stats. Identities = 85/404 (21%), Positives = 142/404 (35%), Gaps = 68/404 (17%) Query 468 DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVR 527 G +LI S S L+V Q Q ++ + I D +F + Sbjct 148 HGSFLIRESESTAGSFSLSVRDFDQN----QGEVVKHYKIRNLDNGGFYISPRITFSGLH 203 Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587 EL + C L R C Q P+ V ++ Sbjct 204 ELVRHYTNA---SDGLCTRLSRPCQTQ---------------KPQKPWWE--DEWEVPRE 243 Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + + LG G V+ G + +V +K L Sbjct 244 TLKLVERLGAGQFGEVWMG-------------------------YYNEHTKVAVKSLKQG 278 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HV 706 AF A+LM Q+ H L ++ V ++TEY+E+G L +L+ G + Sbjct 279 SMSP-DAFLAEANLMKQLQHKRLVRLYAVVTE-EPIYIITEYMENGSLVDFLKTPSGIKL 336 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + + +A Q+ +++LE +N +H ++ NIL++ + K++D G+ Sbjct 337 TINKLLDMAAQIVEGMAFLEERNYIHRDLRAANILVS-------DTLSCKIADFGLARLI 389 Query 767 LSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 E I W APE + G + + D W FG + EI G P + Sbjct 390 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILMTEIVTHGRIPYPGMTNP 447 Query 822 EKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 E +R +R+ P+ +L L QC P RP+F + Sbjct 448 EVIQNLERGYRMPRPDNCPEELYKLMMQCWRERPDDRPTFDYLR 491 >sp|P42683|LCK_CHICK Proto-oncogene tyrosine-protein kinase LCK OS=Gallus gallus OX=9031 GN=LCK PE=2 SV=2 Length=508 Score = 291 bits (744), Expect = 1e-85, Method: Composition-based stats. Identities = 91/414 (22%), Positives = 153/414 (37%), Gaps = 71/414 (17%) Query 460 VQAKLRPE---DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVL 516 +A+L G +LI S + L+V Q Q ++ + I D Sbjct 136 AEARLLASGNTHGSFLIRESETSKGSYSLSVRDFDQN----QGETVKHYKIRNMDNGGYY 191 Query 517 EGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL 576 +F S+ EL + C L + C Q P+ Sbjct 192 ISPRVTFSSLHELVEYYSSS---SDGLCTRLGKPCRTQ---------------KPQKPWW 233 Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 V ++ + + LG G V+ G Sbjct 234 Q--DEWEVPRESLKLVEKLGAGQFGEVWMG-------------------------FYNGH 266 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +V +K L + AF A+LM + H L ++ V + ++TEY+E G L Sbjct 267 TKVAIKNLKQGSMSPS-AFLAEANLMKNLQHPRLVRLYAVVTK-EPIYIITEYMEKGSLV 324 Query 697 VWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +L+ G + + + +A Q+A ++++E KN +H ++ NIL++ + Sbjct 325 DFLKTSEGIKLSINKLLDMAAQIAEGMAFIEAKNYIHRDLRAANILVSE-------ALCC 377 Query 756 KLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ E I W APE + G + + D W FG L EI Sbjct 378 KIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEIVTY 435 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 G P + E +R +R+P+P +CPQ L L QC +P +RP+F + Sbjct 436 GRIPYPGMTNPEVIQNLERGYRMPQPDNCPQELYELMMQCWKEQPEERPTFEYM 489 Score = 285 bits (730), Expect = 8e-84, Method: Composition-based stats. Identities = 99/296 (33%), Positives = 149/296 (50%), Gaps = 29/296 (10%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 D + LK + LG G FG+V + Y+ VA+K LK G S + Sbjct 234 QDEWEVPRESLKLVEKLGAGQFGEVWMGFYNGH-----TKVAIKNLKQ--GSMSPSAFLA 286 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLF 1003 E ++++ L H +++ ++ + ++ EY+ GSL D+L + + +LL Sbjct 287 EANLMKNLQHPRLVRLYAVV---TKEPIYIITEYMEKGSLVDFLKTSEGIKLSINKLLDM 343 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 A QI EGMA++ A++YIHRDL A N+L+ KI DFGLA+ + + Y RE Sbjct 344 AAQIAEGMAFIEAKNYIHRDLRAANILVSEALCCKIADFGLARLIEDNE--YTAREGAKF 401 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 P+ W APE + F SDVWSFG+ L E++T+ I MT Sbjct 402 PIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTYGR--------------IPYPGMTNPE 447 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 + + LERG R+P+PD CP E+Y LM CW+ + RPTFE + +L+ +GQ Sbjct 448 VIQNLERGYRMPQPDNCPQELYELMMQCWKEQPEERPTFEYMKSVLEDFFTATEGQ 503 >sp|P42689|SRK3_SPOLA Tyrosine-protein kinase SRK3 (Fragment) OS=Spongilla lacustris OX=6055 GN=SRK3 PE=2 SV=1 Length=334 Score = 283 bits (725), Expect = 3e-85, Method: Composition-based stats. Identities = 98/319 (31%), Positives = 154/319 (48%), Gaps = 28/319 (9%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915 RL + + D + ++ R LG+G+FG+V Sbjct 25 SHYMMDADGLAQRLSRPCSRANIPITSGLSYKDEWEIDRTTIQLQRKLGQGNFGEVWAGV 84 Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 ++ T VAVK LK D + QE +++ ++H ++++ C + + Sbjct 85 WNGT-----TAVAVKTLKPDT--MEVKDFVQEAQVMKKIHHPNLLQLYAVCTIG--EPIY 135 Query 976 LVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032 +V E + GS+ +YL +I L Q++ + QI GM YL A YIHRDLAARN+L+ Sbjct 136 IVTELMKYGSMLEYLKHGEGKNITLHQMVDMSAQIASGMTYLEAHSYIHRDLAARNILVG 195 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 + K+ DFGLA+ + E + Y RE P+ W APE +F SDVWSFGV + Sbjct 196 EGNVCKVADFGLARVIKE--DIYNPREGTKFPIKWTAPEAALYNRFTIKSDVWSFGVLIS 253 Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152 E++TH + MT ++ E ++RG R+P P+ CP +Y +M +CW Sbjct 254 EIVTHGR--------------MPYPGMTNRQVLEAVDRGYRMPCPEGCPDPLYKIMLSCW 299 Query 1153 ETEASFRPTFENLIPILKT 1171 + E RPTFE+L +L+ Sbjct 300 KHEPDDRPTFESLKNLLED 318 Score = 275 bits (702), Expect = 4e-82, Method: Composition-based stats. Identities = 81/366 (22%), Positives = 135/366 (37%), Gaps = 60/366 (16%) Query 507 IEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRG 566 I D SFP+++ L + ++ A L R C Sbjct 1 IRTLDDGGFYMANRISFPTLQNLVSHY---MMDADGLAQRLSRPC--------------S 43 Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 P T LS +D+ I LGQG V+ G Sbjct 44 RANIPITSGLSYKDEWEIDRTTIQLQRKLGQGNFGEVWAGVWNGT--------------- 88 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 V +K L P ++ F + A +M ++ H +L ++ VC G +V Sbjct 89 ----------TAVAVKTLKPDTMEV-KDFVQEAQVMKKIHHPNLLQLYAVCTIGEPIYIV 137 Query 687 TEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 TE +++G + +L+ G + + + ++ Q+AS ++YLE + +H ++ RNIL+ Sbjct 138 TELMKYGSMLEYLKHGEGKNITLHQMVDMSAQIASGMTYLEAHSYIHRDLAARNILVGEG 197 Query 746 GLAEGTSPFIKLSDPGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGF 800 + K++D G+ RE I W APE N + D W F Sbjct 198 NV-------CKVADFGLARVIKEDIYNPREGTKFPIKWTAPEAAL--YNRFTIKSDVWSF 248 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPS 858 G + EI G P + + R +R+P P L + C +EP RP+ Sbjct 249 GVLISEIVTHGRMPYPGMTNRQVLEAVDRGYRMPCPEGCPDPLYKIMLSCWKHEPDDRPT 308 Query 859 FRTILR 864 F ++ Sbjct 309 FESLKN 314 >sp|Q01621|LCK_RAT Proto-oncogene tyrosine-protein kinase LCK OS=Rattus norvegicus OX=10116 GN=Lck PE=1 SV=3 Length=509 Score = 289 bits (740), Expect = 4e-85, Method: Composition-based stats. Identities = 84/404 (21%), Positives = 143/404 (35%), Gaps = 68/404 (17%) Query 468 DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVR 527 G +LI S S L+V Q Q ++ + I D +FP + Sbjct 148 HGSFLIRESESTAGSFSLSVRDFDQN----QGEVVKHYKIRNLDNGGFYISPRITFPGLH 203 Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587 +L + C L R C Q P+ V ++ Sbjct 204 DLVRHYTNA---SDGLCTKLSRPCQTQ---------------KPQKPWWE--DEWEVPRE 243 Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + + LG G V+ G +V +K L Sbjct 244 TLKLVERLGAGQFGEVWMG-------------------------YYNGHTKVAVKSLKQG 278 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HV 706 AF A+LM Q+ H L ++ V + ++TEY+E+G L +L+ G + Sbjct 279 SMSP-DAFLAEANLMKQLQHPRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIKL 336 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + + +A Q+A ++++E +N +H ++ NIL++ + K++D G+ Sbjct 337 NVNKLLDMAAQIAEGMAFIEEQNYIHRDLRAANILVS-------DTLSCKIADFGLARLI 389 Query 767 LSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 E I W APE + G + + D W FG L EI G P + Sbjct 390 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP 447 Query 822 EKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 E ++ +R+ P+ +L L C P RP+F + Sbjct 448 EVIQNLEKGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLR 491 Score = 288 bits (738), Expect = 7e-85, Method: Composition-based stats. Identities = 100/293 (34%), Positives = 147/293 (50%), Gaps = 29/293 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + LK + LG G FG+V + Y+ VAVK+LK G + E + Sbjct 238 WEVPRETLKLVERLGAGQFGEVWMGYYNGH-----TKVAVKSLKQ--GSMSPDAFLAEAN 290 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQ 1006 +++ L H +++ ++ + ++ EY+ GSL D+L S + + +LL A Q Sbjct 291 LMKQLQHPRLVRLYAVV---TQEPIYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQ 347 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I EGMA++ Q+YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ Sbjct 348 IAEGMAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIK 405 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE + F SDVWSFG+ L E++TH I MT + + Sbjct 406 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQ 451 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 LE+G R+ RPD CP E+YHLM CW+ RPTF+ L +L +GQ Sbjct 452 NLEKGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLDDFFTATEGQ 504 >sp|P06240|LCK_MOUSE Proto-oncogene tyrosine-protein kinase LCK OS=Mus musculus OX=10090 GN=Lck PE=1 SV=4 Length=509 Score = 289 bits (740), Expect = 4e-85, Method: Composition-based stats. Identities = 85/404 (21%), Positives = 143/404 (35%), Gaps = 68/404 (17%) Query 468 DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVR 527 G +LI S S L+V Q Q ++ + I D +FP + Sbjct 148 HGSFLIRESESTAGSFSLSVRDFDQN----QGEVVKHYKIRNLDNGGFYISPRITFPGLH 203 Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587 +L + C L R C Q P+ V ++ Sbjct 204 DLVRHYTNA---SDGLCTKLSRPCQTQ---------------KPQKPWWE--DEWEVPRE 243 Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + + LG G V+ G +V +K L Sbjct 244 TLKLVERLGAGQFGEVWMG-------------------------YYNGHTKVAVKSLKQG 278 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HV 706 AF A+LM Q+ H L ++ V + ++TEY+E+G L +L+ G + Sbjct 279 SMSP-DAFLAEANLMKQLQHPRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIKL 336 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + + +A Q+A ++++E +N +H ++ NIL++ + K++D G+ Sbjct 337 NVNKLLDMAAQIAEGMAFIEEQNYIHRDLRAANILVS-------DTLSCKIADFGLARLI 389 Query 767 LSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 E I W APE + G + + D W FG L EI G P + Sbjct 390 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP 447 Query 822 EKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 E +R +R+ P+ +L L C P RP+F + Sbjct 448 EVIQNLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLR 491 Score = 288 bits (738), Expect = 8e-85, Method: Composition-based stats. Identities = 101/293 (34%), Positives = 147/293 (50%), Gaps = 29/293 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + LK + LG G FG+V + Y+ VAVK+LK G + E + Sbjct 238 WEVPRETLKLVERLGAGQFGEVWMGYYNGH-----TKVAVKSLKQ--GSMSPDAFLAEAN 290 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQ 1006 +++ L H +++ ++ + ++ EY+ GSL D+L S + + +LL A Q Sbjct 291 LMKQLQHPRLVRLYAVV---TQEPIYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQ 347 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I EGMA++ Q+YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ Sbjct 348 IAEGMAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIK 405 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE + F SDVWSFG+ L E++TH I MT + + Sbjct 406 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQ 451 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 LERG R+ RPD CP E+YHLM CW+ RPTF+ L +L +GQ Sbjct 452 NLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLDDFFTATEGQ 504 >sp|Q95M30|HCK_MACFA Tyrosine-protein kinase HCK OS=Macaca fascicularis OX=9541 GN=HCK PE=2 SV=3 Length=504 Score = 288 bits (738), Expect = 6e-85, Method: Composition-based stats. Identities = 81/447 (18%), Positives = 154/447 (34%), Gaps = 71/447 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502 + + + +L G ++I S + L+V Q + Sbjct 118 ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDP----RQGDTV 173 Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562 + + I D +F +++EL + + C L C+ Sbjct 174 KHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKG---SDGLCQKLSVPCV---------- 220 Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 S + + + ++ + LG G V+ Sbjct 221 -------SSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMAT--------------- 258 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 + +V +K + P + AF A+LM + H L +H V + Sbjct 259 ----------YNKHTKVAVKTMKPGSMSV-EAFLAEANLMKTLQHDKLVKLHAVVTK-EP 306 Query 683 NIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 ++TE++ G L +L+ + G P+ + + Q+A ++++E +N +H ++ NIL Sbjct 307 IYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANIL 366 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMD 796 ++ S K++D G+ E I W APE + G++++ D Sbjct 367 VS-------ASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGSSTI--KSD 417 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854 W FG L+EI G P S E +R +R+ PE +L + +C P Sbjct 418 VWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPE 477 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVN 881 +RP+F I L + Sbjct 478 ERPTFEYIQSVLDDFYTATESQYQQQP 504 Score = 282 bits (722), Expect = 1e-82, Method: Composition-based stats. Identities = 95/293 (32%), Positives = 147/293 (50%), Gaps = 29/293 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + LK + LG G FG+V + Y N T VAVK +K G + E + Sbjct 233 WEIPRESLKLEKKLGAGQFGEVWMATY---NKHT--KVAVKTMKP--GSMSVEAFLAEAN 285 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQ 1006 +++TL H+ ++K ++ + ++ E++ GSL D+L L +L+ F+ Q Sbjct 286 LMKTLQHDKLVKLHAVV---TKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ 342 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I EGMA++ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ Sbjct 343 IAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNE--YTAREGAKFPIK 400 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE + SDVWSFG+ L E++T+ I M+ + Sbjct 401 WTAPEAINFGSSTIKSDVWSFGILLMEIVTYGR--------------IPYPGMSNPEVIR 446 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 LERG R+PRP+ CP E+Y++M CW+ RPTFE + +L + + Q Sbjct 447 ALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQ 499 >sp|P00542|FES_FSVGA Tyrosine-protein kinase transforming protein Fes OS=Feline sarcoma virus (strain Gardner-Arnstein) OX=11774 GN=V-FES PE=3 SV=1 Length=609 Score = 292 bits (747), Expect = 7e-85, Method: Composition-based stats. Identities = 111/451 (25%), Positives = 174/451 (39%), Gaps = 85/451 (19%) Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQ-AKLRPEDGLYLIHWSTSHPYRLILTVAQRSQ 492 L EV P + HG L P + A+L G +L+ S +L+V Sbjct 234 LVPEVQKPL---HEQLWYHGAL--PRAEVAELLTHSGDFLVRESQGKQ-EYVLSV----- 282 Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552 DG R F I+ D + EG G F S+ L L LR+ Sbjct 283 LWDGQP----RHFIIQSADNLYRPEGDG--FASIPLLVDHL----LRS------------ 320 Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 QP + I++ A + ++ +++ +G+G V+ GRLR + Sbjct 321 QQPLTKKSGIVLNRAVPKDK---------WVLNHEDLVLGEQIGRGNFGEVFSGRLRADN 371 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLA 671 V +K + DI F + A ++ Q SH ++ Sbjct 372 ------------------------TLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIV 407 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 + GVC + +V E V+ G +LR E + M + + A+ + YLE+K + Sbjct 408 RLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCI 467 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLP 785 H ++ RN L+ + +K+SD G+ A + W APE L Sbjct 468 HRDLAARNCLVTEKNV-------LKISDFGMSREAADGIYAASGGLRQVPVKWTAPEALN 520 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LAT 843 G S+ D W FG L E G +P + S + F ++ RLP P CP + Sbjct 521 YG--RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFR 578 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 L QC YEP QRPSF I ++L ++ + Sbjct 579 LMEQCWAYEPGQRPSFSAIYQELQSIRKRHR 609 Score = 273 bits (699), Expect = 2e-78, Method: Composition-based stats. Identities = 87/294 (30%), Positives = 139/294 (47%), Gaps = 23/294 (8%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 D V + L +G G+FG+V N +VAVK+ + P ++ + Sbjct 337 PKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADN----TLVAVKSCRETLPPDIKAKFL 392 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLF 1003 QE IL+ H +I++ G C + + + +VME V G +L + + LL Sbjct 393 QEAKILKQYSHPNIVRLIGVCTQK--QPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQM 450 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 GM YL ++ IHRDLAARN L+ ++KI DFG+++ +G Y Sbjct 451 VGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREAADGI-YAASGGLRQV 509 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 PV W APE L ++ SDVWSFG+ L+E + L ++ + Sbjct 510 PVKWTAPEALNYGRYSSESDVWSFGILLWETFS--------------LGASPYPNLSNQQ 555 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 E +E+G RLP P+ CP V+ LM+ CW E RP+F + L+++ ++++ Sbjct 556 TREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQELQSIRKRHR 609 >sp|P29320|EPHA3_HUMAN Ephrin type-A receptor 3 OS=Homo sapiens OX=9606 GN=EPHA3 PE=1 SV=2 Length=983 Score = 300 bits (769), Expect = 9e-85, Method: Composition-based stats. Identities = 88/339 (26%), Positives = 155/339 (46%), Gaps = 24/339 (7%) Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR----- 895 + L + Y+ + + L+ L + + + + Sbjct 560 IYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDAT 619 Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 + + +G G FG+V + VA+K LK + R + E I+ Sbjct 620 NISIDKVVGAGEFGEVCSGRLKLPSKKE-ISVAIKTLKVGYTEKQRRDFLGEASIMGQFD 678 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAY 1013 H +II+ +G K + +V EY+ GSL +L +H + QL+ + I GM Y Sbjct 679 HPNIIRLEGVVTKS--KPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKY 736 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 L Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W +PE + Sbjct 737 LSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAI 796 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 KF ASDVWS+G+ L+E++++ + +M+ + + ++ G R Sbjct 797 AYRKFTSASDVWSYGIVLWEVMSYGER--------------PYWEMSNQDVIKAVDEGYR 842 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 LP P CP +Y LM +CW+ + + RP FE ++ IL + Sbjct 843 LPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKL 881 Score = 273 bits (699), Expect = 2e-75, Method: Composition-based stats. Identities = 74/302 (25%), Positives = 121/302 (40%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D I+ +G G V GRL++ +E+ V + Sbjct 614 KELDATNISIDKVVGAGEFGEVCSGRLKLPSK---------------------KEISVAI 652 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +LR Sbjct 653 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLR 712 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + + + + + +AS + YL + VH ++ RNIL+ ++ K+SD Sbjct 713 KHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 765 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E I W +PE + ++A D W +G L E+ GE Sbjct 766 GLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIA--YRKFTSASDVWSYGIVLWEVMSYGER 823 Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + +RLP P CP L L C + RP F I+ L +L Sbjct 824 PYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIR 883 Query 872 HN 873 + Sbjct 884 NP 885 >sp|P00544|FGR_FSVGR Tyrosine-protein kinase transforming protein Fgr OS=Feline sarcoma virus (strain Gardner-Rasheed) OX=11775 GN=V-FGR PE=3 SV=1 Length=545 Score = 289 bits (740), Expect = 9e-85, Method: Composition-based stats. Identities = 88/450 (20%), Positives = 153/450 (34%), Gaps = 71/450 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + G + + +L G +L+ S + L++ Sbjct 156 VAPVDSIQA-EEWYFGKIGRKDAERQLLSPGNARGAFLVRESETTKGAYSLSIRDW---- 210 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D + ++ + I + D F SV+EL C L C Sbjct 211 DEARGDHVKHYKIRKLDTGGYYITTRAQFNSVQELVQHYVEVN---DGLCHLLTAAC--- 264 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P+T+ L++ + + IT LG G +V+ G Sbjct 265 ------------TTMKPQTMGLAK-DAWEISRSSITLQRRLGTGCFGDVWLGMWNGS--- 308 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +V +K L P + E A +M + H L ++ Sbjct 309 ----------------------TKVAVKTLKPGTMSPKAS-LEEAQIMKLLRHDKLVQLY 345 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHG 733 V +VTE++ HG L +L+ + G + + + +A Q+A ++Y+E + +H Sbjct 346 AVVPE-EPIYIVTEFMCHGSLLEFLKDQEGQDLTLPQLVDMAAQVAEGMAYMERMDYIHR 404 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGGA 788 ++ NIL+ G K++D G+ E I W APE G Sbjct 405 DLRAANILV-------GERLVCKIADFGLARLIEDNEYNPRQGAKFPIKWTAPEAALFG- 456 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTS 846 + D W FG L E+ G P + E + + +P P CP L Sbjct 457 -RFTIKSDVWSFGILLTELISKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEAME 515 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 Q +P +RP+F + L + Sbjct 516 QTWRLDPEERPTFEYLQSFLEDYFNGPQQN 545 Score = 265 bits (677), Expect = 5e-76, Method: Composition-based stats. Identities = 90/300 (30%), Positives = 134/300 (45%), Gaps = 29/300 (10%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 + A D + + R LG G FG V L ++ + VAVK LK Sbjct 264 CTTMKPQTMGLAKDAWEISRSSITLQRRLGTGCFGDVWLGMWNGS-----TKVAVKTLKP 318 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993 G +E I++ L H+ +++ E+ + +V E++ GSL ++L Sbjct 319 --GTMSPKASLEEAQIMKLLRHDKLVQLYAVV---PEEPIYIVTEFMCHGSLLEFLKDQE 373 Query 994 --SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 + L QL+ A Q+ EGMAY+ YIHRDL A N+L+ + KI DFGLA+ + + Sbjct 374 GQDLTLPQLVDMAAQVAEGMAYMERMDYIHRDLRAANILVGERLVCKIADFGLARLIEDN 433 Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111 Y R+ P+ W APE +F SDVWSFG+ L EL++ Sbjct 434 E--YNPRQGAKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELISKGR------------ 479 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + M + E +E G +P P CP +Y M+ W + RPTFE L L+ Sbjct 480 --VPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYLQSFLED 537 >sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens OX=9606 GN=ABL1 PE=1 SV=4 Length=1130 Score = 303 bits (775), Expect = 1e-84, Method: Composition-based stats. Identities = 96/436 (22%), Positives = 159/436 (36%), Gaps = 70/436 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 HGP+ + L +G +L+ S S P + +++ R+ Sbjct 123 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG---------RVYH 173 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + I + F ++ EL A +L Sbjct 174 YRINTASDGKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPK----------- 219 Query 565 RGARASPRTLNLSQ-LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 R P +S +++ +IT LG G VYEG + Sbjct 220 ---RNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYS----------- 265 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 L V +K L ++ F + A++M ++ H +L + GVC R P Sbjct 266 -------------LTVAVKTLKEDTMEV-EEFLKEAAVMKEIKHPNLVQLLGVCTREPPF 311 Query 684 IMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 ++TE++ +G L +LR R V + +A Q++SA+ YLE KN +H ++ RN L+ Sbjct 312 YIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV 371 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDK 797 G + +K++D G+ I W APE L N S D Sbjct 372 -------GENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLA--YNKFSIKSDV 422 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855 W FG L EI G +P S+ ++ +R+ PE ++ L C + P+ Sbjct 423 WAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSD 482 Query 856 RPSFRTILRDLTRLQP 871 RPSF I + + Sbjct 483 RPSFAEIHQAFETMFQ 498 Score = 294 bits (753), Expect = 8e-82, Method: Composition-based stats. Identities = 95/310 (31%), Positives = 149/310 (48%), Gaps = 27/310 (9%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 P + TV SP D + + LG G +G+V + + VA Sbjct 214 HYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSL----TVA 269 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 VK LK D + +E +++ + H ++++ G C E ++ E++ G+L D Sbjct 270 VKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLD 325 Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 YL R + LL A QI M YL +++IHRDLAARN L+ + LVK+ DFGL+ Sbjct 326 YLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLS 385 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + Y P+ W APE L KF SDVW+FGV L+E+ T+ S Sbjct 386 RLMT--GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMS----- 438 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + ++ ELLE+ R+ RP+ CP +VY LM+ CW+ S RP+F + Sbjct 439 ---------PYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 489 Query 1166 IPILKTVHEK 1175 +T+ ++ Sbjct 490 HQAFETMFQE 499 >sp|P00520|ABL1_MOUSE Tyrosine-protein kinase ABL1 OS=Mus musculus OX=10090 GN=Abl1 PE=1 SV=3 Length=1123 Score = 303 bits (775), Expect = 1e-84, Method: Composition-based stats. Identities = 96/436 (22%), Positives = 159/436 (36%), Gaps = 70/436 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 HGP+ + L +G +L+ S S P + +++ R+ Sbjct 123 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG---------RVYH 173 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + I + F ++ EL A +L Sbjct 174 YRINTASDGKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPK----------- 219 Query 565 RGARASPRTLNLSQ-LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 R P +S +++ +IT LG G VYEG + Sbjct 220 ---RNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYS----------- 265 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 L V +K L ++ F + A++M ++ H +L + GVC R P Sbjct 266 -------------LTVAVKTLKEDTMEV-EEFLKEAAVMKEIKHPNLVQLLGVCTREPPF 311 Query 684 IMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 ++TE++ +G L +LR R V + +A Q++SA+ YLE KN +H ++ RN L+ Sbjct 312 YIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV 371 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDK 797 G + +K++D G+ I W APE L N S D Sbjct 372 -------GENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLA--YNKFSIKSDV 422 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855 W FG L EI G +P S+ ++ +R+ PE ++ L C + P+ Sbjct 423 WAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSD 482 Query 856 RPSFRTILRDLTRLQP 871 RPSF I + + Sbjct 483 RPSFAEIHQAFETMFQ 498 Score = 295 bits (755), Expect = 5e-82, Method: Composition-based stats. Identities = 94/310 (30%), Positives = 149/310 (48%), Gaps = 27/310 (9%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 P + T+ SP D + + LG G +G+V + + VA Sbjct 214 HYPAPKRNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSL----TVA 269 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 VK LK D + +E +++ + H ++++ G C E ++ E++ G+L D Sbjct 270 VKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTR--EPPFYIITEFMTYGNLLD 325 Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 YL R + LL A QI M YL +++IHRDLAARN L+ + LVK+ DFGL+ Sbjct 326 YLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLS 385 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + Y P+ W APE L KF SDVW+FGV L+E+ T+ S Sbjct 386 RLMT--GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMS----- 438 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + ++ ELLE+ R+ RP+ CP +VY LM+ CW+ S RP+F + Sbjct 439 ---------PYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 489 Query 1166 IPILKTVHEK 1175 +T+ ++ Sbjct 490 HQAFETMFQE 499 >sp|P06239|LCK_HUMAN Tyrosine-protein kinase Lck OS=Homo sapiens OX=9606 GN=LCK PE=1 SV=6 Length=509 Score = 288 bits (737), Expect = 1e-84, Method: Composition-based stats. Identities = 99/293 (34%), Positives = 149/293 (51%), Gaps = 29/293 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + LK + LG G FG+V + Y+ VAVK+LK G + E + Sbjct 238 WEVPRETLKLVERLGAGQFGEVWMGYYNGH-----TKVAVKSLKQ--GSMSPDAFLAEAN 290 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQ 1006 +++ L H+ +++ ++ + ++ EY+ GSL D+L S + + +LL A Q Sbjct 291 LMKQLQHQRLVRLYAVV---TQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQ 347 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I EGMA++ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ Sbjct 348 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIK 405 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE + F SDVWSFG+ L E++TH I MT + + Sbjct 406 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQ 451 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 LERG R+ RPD CP E+Y LM+ CW+ RPTF+ L +L+ +GQ Sbjct 452 NLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATEGQ 504 Score = 287 bits (734), Expect = 2e-84, Method: Composition-based stats. Identities = 86/404 (21%), Positives = 143/404 (35%), Gaps = 68/404 (17%) Query 468 DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVR 527 G +LI S S L+V Q Q ++ + I D +FP + Sbjct 148 HGSFLIRESESTAGSFSLSVRDFDQN----QGEVVKHYKIRNLDNGGFYISPRITFPGLH 203 Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587 EL + C L R C Q P+ V ++ Sbjct 204 ELVRHYTNA---SDGLCTRLSRPCQTQ---------------KPQKPWWE--DEWEVPRE 243 Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + + LG G V+ G +V +K L Sbjct 244 TLKLVERLGAGQFGEVWMG-------------------------YYNGHTKVAVKSLKQG 278 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HV 706 AF A+LM Q+ H L ++ V + ++TEY+E+G L +L+ G + Sbjct 279 SMSP-DAFLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIKL 336 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + + +A Q+A ++++E +N +H ++ NIL++ + K++D G+ Sbjct 337 TINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS-------DTLSCKIADFGLARLI 389 Query 767 LSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 E I W APE + G + + D W FG L EI G P + Sbjct 390 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP 447 Query 822 EKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 E +R +R+ P+ +L L C P RP+F + Sbjct 448 EVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLR 491 >sp|Q5PXS1|LCK_AOTNA Tyrosine-protein kinase Lck OS=Aotus nancymaae OX=37293 GN=LCK PE=2 SV=4 Length=509 Score = 288 bits (736), Expect = 1e-84, Method: Composition-based stats. Identities = 103/293 (35%), Positives = 151/293 (52%), Gaps = 29/293 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + LK + LG G FG+V + Y ND T VAVK+LK G + E + Sbjct 238 WEVPRETLKLVERLGAGQFGEVWMGYY---NDHT--KVAVKSLKQ--GSMSPDAFLAEAN 290 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQ 1006 +++ L H+ +++ ++ + ++ EY+ GSL D+L S + + +LL A Q Sbjct 291 LMKQLQHQRLVRLYAVV---TQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQ 347 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I EGMA++ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ Sbjct 348 IAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIK 405 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE + F SDVWSFG+ L E++TH I MT + + Sbjct 406 WTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR--------------IPYPGMTNPEVIQ 451 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 LERG R+ RPD CP E+YHLM CW+ RPTF+ L +L+ +GQ Sbjct 452 NLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLEDFFTATEGQ 504 Score = 286 bits (731), Expect = 6e-84, Method: Composition-based stats. Identities = 86/404 (21%), Positives = 143/404 (35%), Gaps = 68/404 (17%) Query 468 DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVR 527 G +LI S S L+V Q Q ++ + I D +FP + Sbjct 148 HGSFLIRESESTAGSFSLSVRDFDQN----QGEVVKHYKIRNLDNGGFYISPRITFPGLH 203 Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587 EL + C L R C Q P+ V ++ Sbjct 204 ELVRHYTNA---SDGLCTRLSRPCQTQ---------------KPQKPWWE--DEWEVPRE 243 Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + + LG G V+ G +V +K L Sbjct 244 TLKLVERLGAGQFGEVWMG-------------------------YYNDHTKVAVKSLKQG 278 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HV 706 AF A+LM Q+ H L ++ V + ++TEY+E+G L +L+ G + Sbjct 279 SMSP-DAFLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIKL 336 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + + +A Q+A ++++E +N +H ++ NIL++ + K++D G+ Sbjct 337 TINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVS-------DTLSCKIADFGLARLI 389 Query 767 LSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 E I W APE + G + + D W FG L EI G P + Sbjct 390 EDNEYTAREGAKFPIKWTAPEAINYG--TFTIKSDVWSFGILLTEIVTHGRIPYPGMTNP 447 Query 822 EKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 E +R +R+ P+ +L L C P RP+F + Sbjct 448 EVIQNLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLR 491 >sp|P54756|EPHA5_HUMAN Ephrin type-A receptor 5 OS=Homo sapiens OX=9606 GN=EPHA5 PE=1 SV=3 Length=1037 Score = 301 bits (770), Expect = 2e-84, Method: Composition-based stats. Identities = 91/352 (26%), Positives = 157/352 (45%), Gaps = 24/352 (7%) Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR-----YL 897 +L +C + Q P + ++ + + + + + + Sbjct 616 SLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCI 675 Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 R +G G FG+V VA+K LK + R + E I+ H Sbjct 676 TIERVIGAGEFGEVCSGRLKLPGKRE-LPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHP 734 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015 +II +G K + +V EY+ GSL +L ++ + QL+ + I GM YL Sbjct 735 NIIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLS 792 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W APE + Sbjct 793 DMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAF 852 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF ASDVWS+G+ ++E++++ + +MT + + +E G RLP Sbjct 853 RKFTSASDVWSYGIVMWEVVSYGER--------------PYWEMTNQDVIKAVEEGYRLP 898 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC 1187 P CP +Y LM +CW+ E + RP F+ ++ +L + V + C Sbjct 899 SPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASC 950 Score = 270 bits (691), Expect = 4e-74, Method: Composition-based stats. Identities = 73/302 (24%), Positives = 123/302 (41%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 ++ IT +G G V GRL++ G +EL V + Sbjct 668 KEIEASCITIERVIGAGEFGEVCSGRLKLPGK---------------------RELPVAI 706 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +L+ Sbjct 707 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLK 766 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +++ + YL + VH ++ RNIL+ ++ K+SD Sbjct 767 KNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 819 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E I W APE + ++A D W +G + E+ GE Sbjct 820 GLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--FRKFTSASDVWSYGIVMWEVVSYGER 877 Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P + + + +RLP CP L L C E RP F I+ L +L Sbjct 878 PYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIR 937 Query 872 HN 873 + Sbjct 938 NP 939 >sp|P08631|HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo sapiens OX=9606 GN=HCK PE=1 SV=5 Length=526 Score = 288 bits (736), Expect = 2e-84, Method: Composition-based stats. Identities = 81/447 (18%), Positives = 151/447 (34%), Gaps = 71/447 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502 + + + +L G ++I S + L+V Q + Sbjct 140 ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDP----RQGDTV 195 Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562 + + I D +F +++EL + C L C+ Sbjct 196 KHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGN---DGLCQKLSVPCM---------- 242 Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 S + + + ++ + LG G V+ Sbjct 243 -------SSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMAT--------------- 280 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 + +V +K + P + AF A++M + H L +H V + Sbjct 281 ----------YNKHTKVAVKTMKPGSMSV-EAFLAEANVMKTLQHDKLVKLHAVVTK-EP 328 Query 683 NIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 ++TE++ G L +L+ + G P+ + + Q+A ++++E +N +H ++ NIL Sbjct 329 IYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANIL 388 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMD 796 ++ S K++D G+ E I W APE + G S + D Sbjct 389 VS-------ASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFG--SFTIKSD 439 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854 W FG L+EI G P S E +R +R+ PE +L + +C P Sbjct 440 VWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPE 499 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVN 881 +RP+F I L + Sbjct 500 ERPTFEYIQSVLDDFYTATESQYQQQP 526 Score = 283 bits (725), Expect = 7e-83, Method: Composition-based stats. Identities = 98/314 (31%), Positives = 154/314 (49%), Gaps = 29/314 (9%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 Q ++ + + D + LK + LG G FG+V + Y N T VA Sbjct 234 CQKLSVPCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATY---NKHT--KVA 288 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 VK +K G + E ++++TL H+ ++K ++ + ++ E++ GSL D Sbjct 289 VKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKLHAVV---TKEPIYIITEFMAKGSLLD 343 Query 989 YLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L L +L+ F+ QI EGMA++ ++YIHRDL A N+L+ + KI DFGLA Sbjct 344 FLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLA 403 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + Y RE P+ W APE + F SDVWSFG+ L E++T+ Sbjct 404 RVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGR------ 455 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 I M+ + LERG R+PRP+ CP E+Y++M CW+ RPTFE + Sbjct 456 --------IPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYI 507 Query 1166 IPILKTVHEKYQGQ 1179 +L + + Q Sbjct 508 QSVLDDFYTATESQ 521 >sp|P54757|EPHA5_RAT Ephrin type-A receptor 5 OS=Rattus norvegicus OX=10116 GN=Epha5 PE=1 SV=1 Length=1005 Score = 299 bits (765), Expect = 5e-84, Method: Composition-based stats. Identities = 88/337 (26%), Positives = 153/337 (45%), Gaps = 24/337 (7%) Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFH-----KRYL 897 +L +C + Q P + ++ + + + + + Sbjct 618 SLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPTQAVHEFGKEIEASCI 677 Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 R +G G FG+V VA K LK + R + E I+ H Sbjct 678 TIERVIGAGEFGEVCSGRLKLPGKRE-LPVATKTLKVGYTEKQRRDFLSEASIMGQFDHP 736 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015 +II +G K + +V EY+ GSL +L ++ + QL+ + I GM YL Sbjct 737 NIIHLEGVVTKS--KPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGMLRGIAAGMKYLS 794 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 Y+HRDLAARN+L++++ + K+ DFGL++ + + E G P+ W APE + Sbjct 795 DMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAF 854 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 KF ASDVWS+G+ ++E++++ + +MT + + +E G RLP Sbjct 855 RKFTSASDVWSYGIVMWEVVSYGER--------------PYWEMTNQDVIKAVEEGYRLP 900 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P CP +Y LM +CW+ + + RP F++++ +L + Sbjct 901 SPMDCPAALYQLMLDCWQKDRNSRPKFDDIVNMLDKL 937 Score = 271 bits (693), Expect = 1e-74, Method: Composition-based stats. Identities = 73/302 (24%), Positives = 122/302 (40%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 ++ IT +G G V GRL++ G +EL V Sbjct 670 KEIEASCITIERVIGAGEFGEVCSGRLKLPGK---------------------RELPVAT 708 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +L+ Sbjct 709 KTLKVGYTEKQRRDFLSEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLK 768 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL + VH ++ RNIL+ ++ K+SD Sbjct 769 KNDGQFTVIQLVGMLRGIAAGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 821 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E I W APE + ++A D W +G + E+ GE Sbjct 822 GLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--FRKFTSASDVWSYGIVMWEVVSYGER 879 Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P + + + +RLP CP L L C + RP F I+ L +L Sbjct 880 PYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDDIVNMLDKLIR 939 Query 872 HN 873 + Sbjct 940 NP 941 >sp|P29321|EPHA8_RAT Ephrin type-A receptor 8 (Fragment) OS=Rattus norvegicus OX=10116 GN=Epha8 PE=2 SV=1 Length=372 Score = 281 bits (719), Expect = 6e-84, Method: Composition-based stats. Identities = 91/293 (31%), Positives = 140/293 (48%), Gaps = 20/293 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 + +G G G+V VA+KALKA + R + +E I+ H Sbjct 3 HIEKIIGSGESGEVCYGRLQVPGQRD-VPVAIKALKAGYTERQRQDFLREAAIMGQFDHP 61 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015 +II+ +G + +V EY+ GSL +L H + QL+ + + GM YL Sbjct 62 NIIRLEGVVTRG--RLAMIVTEYMENGSLDAFLRTHDGQFTILQLVGMLKGVGAGMRYLS 119 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 YIHRDLAARN+L+D + K+ DFGL++A+ + E G P+ W APE + Sbjct 120 DLGYIHRDLAARNILVDGRLVCKVSDFGLSRALEDDPEAAYTTAGGKIPIRWTAPEAIAF 179 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 F ASDVWSFGV ++E+L + + MT + +E G RLP Sbjct 180 RTFSSASDVWSFGVVMWEVLAYGER--------------PYWNMTNQDVISSVEEGYRLP 225 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV-HEKYQGQAPSVFSVC 1187 P CP ++ LM +CW + + RP F +++ +L+ + H +A + S C Sbjct 226 APMGCPRALHQLMLDCWHKDRAQRPRFSHVVSVLEALVHSPESLRATATVSRC 278 Score = 256 bits (654), Expect = 6e-75, Method: Composition-based stats. Identities = 78/331 (24%), Positives = 128/331 (39%), Gaps = 46/331 (14%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 I +G G V GRL+V G +++ V +K L + Sbjct 2 IHIEKIIGSGESGEVCYGRLQVPGQ---------------------RDVPVAIKALKAGY 40 Query 649 HDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 + F A++M Q H ++ + GV RG ++VTEY+E+G LD +LR G Sbjct 41 TERQRQDFLREAAIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDAFLRTHDGQFT 100 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 + + + + + + + YL + +H ++ RNIL+ K+SD G+ Sbjct 101 ILQLVGMLKGVGAGMRYLSDLGYIHRDLAARNILVD-------GRLVCKVSDFGLSRALE 153 Query 768 SREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 E I W APE + + S+A D W FG + E+ GE P + + Sbjct 154 DDPEAAYTTAGGKIPIRWTAPEAIA--FRTFSSASDVWSFGVVMWEVLAYGERPYWNMTN 211 Query 821 SEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + +RLP CP+ L L C + QRP F ++ L L + Sbjct 212 QDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFSHVVSVLEALVHSPESLRA 271 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 T + + + DL G G Sbjct 272 TATVSRCPAP------AFARSCFDLRAGGNG 296 >sp|P14238|FES_FELCA Tyrosine-protein kinase Fes/Fps OS=Felis catus OX=9685 GN=FES PE=3 SV=2 Length=820 Score = 295 bits (754), Expect = 7e-84, Method: Composition-based stats. Identities = 115/451 (25%), Positives = 177/451 (39%), Gaps = 85/451 (19%) Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQ-AKLRPEDGLYLIHWSTSHPYRLILTVAQRSQ 492 L EV P + HG L P + A+L G +L+ S +L+V Sbjct 445 LVPEVQKPL---HEQLWYHGAL--PRAEVAELLTHSGDFLVRESQGKQ-EYVLSV----- 493 Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552 DG R F IE D + LEG G F S+ L L LR+ Sbjct 494 LWDGQP----RHFIIESADNLYRLEGDG--FASIPLLVDHL----LRS------------ 531 Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 QP + I++ A + ++ +++ +G+G V+ GRLR + Sbjct 532 QQPLTKKSGIVLNRAVPKDK---------WVLNHEDLVLGEQIGRGNFGEVFSGRLRADN 582 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLA 671 V +K + DI F + A ++ Q SH ++ Sbjct 583 ------------------------TLVAVKSCRETLPPDIKAKFLQEAKILKQYSHPNIV 618 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 + GVC + +V E V+ G +LR E + M + + A+ + YLE+K + Sbjct 619 RLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCI 678 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPECLP 785 H ++ RN L+ + +K+SD G+ A S R + W APE L Sbjct 679 HRDLAARNCLVTEKNV-------LKISDFGMSREEADGIYAASGGLRQVPVKWTAPEALN 731 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LAT 843 G S+ D W FG L E G +P + S + F ++ RLP P CP + Sbjct 732 YG--RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFR 789 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 L QC YEP QRPSF I ++L ++ + Sbjct 790 LMEQCWAYEPGQRPSFSAIYQELQSIRKRHR 820 Score = 273 bits (698), Expect = 3e-76, Method: Composition-based stats. Identities = 87/294 (30%), Positives = 139/294 (47%), Gaps = 23/294 (8%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 D V + L +G G+FG+V N +VAVK+ + P ++ + Sbjct 548 PKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADN----TLVAVKSCRETLPPDIKAKFL 603 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLF 1003 QE IL+ H +I++ G C + + + +VME V G +L + + LL Sbjct 604 QEAKILKQYSHPNIVRLIGVCTQK--QPIYIVMELVQGGDFLTFLRTEGARLRMKTLLQM 661 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 GM YL ++ IHRDLAARN L+ ++KI DFG+++ +G Y Sbjct 662 VGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGI-YAASGGLRQV 720 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 PV W APE L ++ SDVWSFG+ L+E + L ++ + Sbjct 721 PVKWTAPEALNYGRYSSESDVWSFGILLWETFS--------------LGASPYPNLSNQQ 766 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 E +E+G RLP P+ CP V+ LM+ CW E RP+F + L+++ ++++ Sbjct 767 TREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSAIYQELQSIRKRHR 820 >sp|Q03145|EPHA2_MOUSE Ephrin type-A receptor 2 OS=Mus musculus OX=10090 GN=Epha2 PE=1 SV=3 Length=977 Score = 297 bits (761), Expect = 1e-83, Method: Composition-based stats. Identities = 86/307 (28%), Positives = 147/307 (48%), Gaps = 18/307 (6%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 L+ + + T H + + + +G G FG+V ++ V Sbjct 585 PLKTYVDPHTYEDPNQAVLKFTTEIHPSCVARQKVIGAGEFGEVYKGTLKASSGKKEIPV 644 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LKA + R + E I+ H +II+ +G K + ++ EY+ G+L Sbjct 645 AIKTLKAGYTEKQRVDFLSEASIMGQFSHHNIIRLEGVVSKY--KPMMIITEYMENGALD 702 Query 988 DYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL+ Sbjct 703 KFLREKDGEFSVLQLVGMLRGIASGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLS 762 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + E G P+ W APE + KF ASDVWS+G+ ++E++T+ + Sbjct 763 RVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMTYGER----- 817 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 +++ + + + G RLP P CP +Y LM CW+ E S RP F ++ Sbjct 818 ---------PYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADI 868 Query 1166 IPILKTV 1172 + IL + Sbjct 869 VSILDKL 875 Score = 270 bits (689), Expect = 5e-74, Method: Composition-based stats. Identities = 76/299 (25%), Positives = 123/299 (41%), Gaps = 39/299 (13%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 + + + +G G VY+G L+ +E+ V Sbjct 606 TTEIHPSCVARQKVIGAGEFGEVYKGTLK--------------------ASSGKKEIPVA 645 Query 641 LKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +K L + + F AS+M Q SH ++ + GV + +++TEY+E+G LD +L Sbjct 646 IKTLKAGYTEKQRVDFLSEASIMGQFSHHNIIRLEGVVSKYKPMMIITEYMENGALDKFL 705 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R + G + + + + +AS + YL N N VH ++ RNIL+ ++ K+SD Sbjct 706 REKDGEFSVLQLVGMLRGIASGMKYLANMNYVHRDLAARNILVN-------SNLVCKVSD 758 Query 760 PGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 G+ E I W APE + ++A D W +G + E+ GE Sbjct 759 FGLSRVLEDDPEATYTTSGGKIPIRWTAPEAIS--YRKFTSASDVWSYGIVMWEVMTYGE 816 Query 813 APLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 P S E RLP CP + L QC E ++RP F I+ L +L Sbjct 817 RPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERSRRPKFADIVSILDKL 875 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens OX=9606 GN=ABL2 PE=1 SV=1 Length=1182 Score = 300 bits (769), Expect = 1e-83, Method: Composition-based stats. Identities = 97/436 (22%), Positives = 158/436 (36%), Gaps = 70/436 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 HGP+ + L +G +L+ S S P +L +++ R+ Sbjct 169 EKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEG---------RVYH 219 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + I V F ++ EL A +L Sbjct 220 YRINTTADGKVYVTAESRFSTLAELVHH---HSTVADGLVTTLHYPAPKC---------- 266 Query 565 RGARASPRTLNLSQL-SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 P +S + +++ +IT LG G VY G + Sbjct 267 ----NKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYS----------- 311 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 L V +K L ++ F + A++M ++ H +L + GVC P Sbjct 312 -------------LTVAVKTLKEDTMEV-EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPF 357 Query 684 IMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +VTEY+ +G L +LR R V + +A Q++SA+ YLE KN +H ++ RN L+ Sbjct 358 YIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV 417 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDK 797 G + +K++D G+ I W APE L N+ S D Sbjct 418 -------GENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLA--YNTFSIKSDV 468 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855 W FG L EI G +P S+ ++ +R+ PE P++ L C + P Sbjct 469 WAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPAD 528 Query 856 RPSFRTILRDLTRLQP 871 RPSF + + Sbjct 529 RPSFAETHQAFETMFH 544 Score = 290 bits (742), Expect = 5e-80, Method: Composition-based stats. Identities = 94/307 (31%), Positives = 148/307 (48%), Gaps = 27/307 (9%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 P + TV SP D + + LG G +G+V + + + VA Sbjct 260 HYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSL----TVA 315 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 VK LK D + +E +++ + H ++++ G C E +V EY+P G+L D Sbjct 316 VKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQLLGVCT--LEPPFYIVTEYMPYGNLLD 371 Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 YL R + LL A QI M YL +++IHRDLAARN L+ + +VK+ DFGL+ Sbjct 372 YLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLS 431 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + Y P+ W APE L F SDVW+FGV L+E+ T+ S Sbjct 432 RLMT--GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMS----- 484 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + ++ +LLE+G R+ +P+ CP +VY LM+ CW+ + RP+F Sbjct 485 ---------PYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAET 535 Query 1166 IPILKTV 1172 +T+ Sbjct 536 HQAFETM 542 >sp|O08680|EPHA3_RAT Ephrin type-A receptor 3 OS=Rattus norvegicus OX=10116 GN=Epha3 PE=2 SV=1 Length=984 Score = 297 bits (761), Expect = 1e-83, Method: Composition-based stats. Identities = 86/306 (28%), Positives = 144/306 (47%), Gaps = 19/306 (6%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 L+ + + + + +G G FG+V + VA Sbjct 594 LRTYVDPHTYEDPTQAVHEFAKELDATNIAIDKVVGAGEFGEVCSGRLKLPSKKE-ISVA 652 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK + R + E I+ H +II+ +G K + +V EY+ GSL Sbjct 653 IKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKS--KPVMIVTEYMENGSLDS 710 Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 +L +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL++ Sbjct 711 FLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSR 770 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 + + E G PV W +PE KF ASDVWS+G+ L+E++++ + Sbjct 771 VLEDDPEAAYTTRGGKIPVRWTSPEATAYRKFTSASDVWSYGIVLWEVMSYGER------ 824 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 +M+ + + ++ G RLP P CP +Y LM +CW+ + + RP FE ++ Sbjct 825 --------PYWEMSNQDVIKAVDEGYRLPLPMDCPAALYQLMLDCWQKDRNNRPKFEQIV 876 Query 1167 PILKTV 1172 IL + Sbjct 877 SILDKL 882 Score = 271 bits (692), Expect = 2e-74, Method: Composition-based stats. Identities = 74/302 (25%), Positives = 120/302 (40%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D I +G G V GRL++ +E+ V + Sbjct 615 KELDATNIAIDKVVGAGEFGEVCSGRLKLPSK---------------------KEISVAI 653 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +LR Sbjct 654 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLR 713 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + + + + + +AS + YL + VH ++ RNIL+ ++ K+SD Sbjct 714 KHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 766 Query 761 GVGLGALSR-----EERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ R +IP W +PE ++A D W +G L E+ GE Sbjct 767 GLSRVLEDDPEAAYTTRGGKIPVRWTSPEA--TAYRKFTSASDVWSYGIVLWEVMSYGER 824 Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + +RLP CP L L C + RP F I+ L +L Sbjct 825 PYWEMSNQDVIKAVDEGYRLPLPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIR 884 Query 872 HN 873 + Sbjct 885 NP 886 >sp|P00522|ABL_DROME Tyrosine-protein kinase Abl OS=Drosophila melanogaster OX=7227 GN=Abl PE=1 SV=3 Length=1620 Score = 303 bits (776), Expect = 2e-83, Method: Composition-based stats. Identities = 100/444 (23%), Positives = 164/444 (37%), Gaps = 69/444 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDG 496 V P + HGP+ + L +G +L+ S S P + +++ Sbjct 243 VTPLNSLEK-HSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEG----- 296 Query 497 MQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPG 556 R+ + I + V F ++ EL L Q Sbjct 297 ----RVYHYRISEDPDGKVFVTQEAKFNTLAELVHHHSVPH-EGHGLITPLLYPAPKQ-- 349 Query 557 ETSNLIIMRGARASPRTLNLS-QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615 P LS + + + +I LG G VYE + G+ Sbjct 350 ------------NKPTVFPLSPEPDEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGN-- 395 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675 V +K L F E A++M ++ H +L + G Sbjct 396 ----------------------TVAVKTLKEDTM-ALKDFLEEAAIMKEMKHPNLVQLIG 432 Query 676 VCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGN 734 VC R P ++TE++ HG L +LR R + + +A Q+AS +SYLE++N +H + Sbjct 433 VCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRD 492 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGAN 789 + RN L+ G + +K++D G+ I W APE L N Sbjct 493 LAARNCLV-------GDNKLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLA--YN 543 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847 ST D W FG L EI G +P + ++ H + +R+ P P++ L Q Sbjct 544 KFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQ 603 Query 848 CLTYEPTQRPSFRTILRDLTRLQP 871 C ++ T RP+F++I L + Sbjct 604 CWQWDATDRPTFKSIHHALEHMFQ 627 Score = 301 bits (771), Expect = 7e-83, Method: Composition-based stats. Identities = 102/310 (33%), Positives = 160/310 (52%), Gaps = 27/310 (9%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 L P + TV P SP D + + LG G +G+V Y+ G VA Sbjct 343 LYPAPKQNKPTVFPLSPEPDEWEICRTDIMMKHKLGGGQYGEV----YEAVWKRYGNTVA 398 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 VK LK D + +E I++ + H ++++ G C E ++ E++ G+L D Sbjct 399 VKTLKEDT--MALKDFLEEAAIMKEMKHPNLVQLIGVCTR--EPPFYIITEFMSHGNLLD 454 Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L R ++ LL A QI GM+YL +++YIHRDLAARN L+ +++LVK+ DFGLA Sbjct 455 FLRSAGRETLDAVALLYMATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLA 514 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + + Y P+ W APE L KF SDVW+FGV L+E+ T+ S Sbjct 515 RLMRD--DTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMS----- 567 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + + L++G R+ RP CP EVY LM+ CW+ +A+ RPTF+++ Sbjct 568 ---------PYPAIDLTDVYHKLDKGYRMERPPGCPPEVYDLMRQCWQWDATDRPTFKSI 618 Query 1166 IPILKTVHEK 1175 L+ + ++ Sbjct 619 HHALEHMFQE 628 >sp|P29318|EPHA3_CHICK Ephrin type-A receptor 3 OS=Gallus gallus OX=9031 GN=EPHA3 PE=1 SV=1 Length=983 Score = 296 bits (758), Expect = 3e-83, Method: Composition-based stats. Identities = 85/306 (28%), Positives = 145/306 (47%), Gaps = 19/306 (6%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 L+ + + + + +G G FG+V + VA Sbjct 593 LRTYVDPHTYEDPNQAVHEFAKELDASNISIDKVVGAGEFGEVCSGRLKLPSKKE-ISVA 651 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LKA + R + E I+ H +II+ +G K + +V EY+ GSL Sbjct 652 IKTLKAGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKS--KPVMIVTEYMENGSLDS 709 Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 +L +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL++ Sbjct 710 FLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSR 769 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 + + E G P+ W +PE + KF ASD WS+G+ L+E++++ + Sbjct 770 VLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDAWSYGIVLWEVMSYGER------ 823 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 +M+ + + ++ G RLP P CP +Y LM +CW+ + + RP FE ++ Sbjct 824 --------PYWEMSFQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIV 875 Query 1167 PILKTV 1172 IL + Sbjct 876 SILDKL 881 Score = 269 bits (688), Expect = 6e-74, Method: Composition-based stats. Identities = 74/302 (25%), Positives = 121/302 (40%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D I+ +G G V GRL++ +E+ V + Sbjct 614 KELDASNISIDKVVGAGEFGEVCSGRLKLPSK---------------------KEISVAI 652 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +LR Sbjct 653 KTLKAGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLR 712 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + + + + + +AS + YL + VH ++ RNIL+ ++ K+SD Sbjct 713 KHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 765 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E I W +PE + ++A D W +G L E+ GE Sbjct 766 GLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIA--YRKFTSASDAWSYGIVLWEVMSYGER 823 Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + +RLP P CP L L C + RP F I+ L +L Sbjct 824 PYWEMSFQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIR 883 Query 872 HN 873 + Sbjct 884 NP 885 >sp|P16879|FES_MOUSE Tyrosine-protein kinase Fes/Fps OS=Mus musculus OX=10090 GN=Fes PE=1 SV=2 Length=822 Score = 293 bits (749), Expect = 4e-83, Method: Composition-based stats. Identities = 107/451 (24%), Positives = 177/451 (39%), Gaps = 85/451 (19%) Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQ-AKLRPEDGLYLIHWSTSHPYRLILTVAQRSQ 492 L EV P + HG + P + A+L G +L+ S +L+V Sbjct 447 LVPEVQKPLY---EQLWYHGAI--PRAEVAELLTHSGDFLVRESQGKQ-EYVLSV----- 495 Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552 DG R F I+ D + LEG G FPS+ L L Sbjct 496 MWDGQP----RHFIIQSSDNLYRLEGDG--FPSIPLLITHLLSS---------------- 533 Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 QP + +++ A + + +++ +G+G V+ GRLR + Sbjct 534 QQPLTKKSGVVLFRAVPKDK---------WVLKHEDLVLGEQIGRGNFGEVFSGRLRADN 584 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLA 671 V +K + D+ F + A ++ Q +H ++ Sbjct 585 ------------------------TPVAVKSCRETLPPDLKAKFLQEARILKQYNHPNIV 620 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 + GVC + +V E V+ G +LR E + + + + A+ + YLE+K + Sbjct 621 RLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCI 680 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIP--WLAPECLP 785 H ++ RN L+ + +K+SD G+ G + + ++P W APE L Sbjct 681 HRDLAARNCLVTEKNV-------LKISDFGMSREEADGIYAASAGLRQVPVKWTAPEALN 733 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LAT 843 G S+ D W FG L E G +P + + + F ++ HRLP P CP + Sbjct 734 YG--RYSSESDVWSFGILLWETFSLGASPYPNLTNQQTREFVEKGHRLPCPELCPDAVFR 791 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 L QC YEP QRPSF I ++L ++ + Sbjct 792 LMEQCWAYEPGQRPSFSIICQELHSIRKRHR 822 Score = 270 bits (691), Expect = 2e-75, Method: Composition-based stats. Identities = 94/331 (28%), Positives = 145/331 (44%), Gaps = 23/331 (7%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 E PS ++ L Q V + D V L +G G+F Sbjct 513 YRLEGDGFPSIPLLITHLLSSQQPLTKKSGVVLFRAVPKDKWVLKHEDLVLGEQIGRGNF 572 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968 G+V N VAVK+ + P ++ + QE IL+ H +I++ G C Sbjct 573 GEVFSGRLRADN----TPVAVKSCRETLPPDLKAKFLQEARILKQYNHPNIVRLIGVCTQ 628 Query 969 QGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 + + + +VME V G +L + + LL GM YL ++ IHRDLAA Sbjct 629 K--QPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAA 686 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RN L+ ++KI DFG+++ +G Y PV W APE L ++ SDVWS Sbjct 687 RNCLVTEKNVLKISDFGMSREEADGI-YAASAGLRQVPVKWTAPEALNYGRYSSESDVWS 745 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 FG+ L+E + L +T + E +E+G RLP P+ CP V+ Sbjct 746 FGILLWETFS--------------LGASPYPNLTNQQTREFVEKGHRLPCPELCPDAVFR 791 Query 1147 LMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 LM+ CW E RP+F + L ++ ++++ Sbjct 792 LMEQCWAYEPGQRPSFSIICQELHSIRKRHR 822 >sp|P00541|FPS_AVISP Tyrosine-protein kinase transforming protein Fps OS=Avian sarcoma virus (strain PRCII) OX=11880 GN=V-FPS PE=3 SV=1 Length=533 Score = 285 bits (728), Expect = 4e-83, Method: Composition-based stats. Identities = 98/436 (22%), Positives = 171/436 (39%), Gaps = 80/436 (18%) Query 448 RDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPI 507 + HG + VQ +L G +L+ S +L+V DG R F I Sbjct 169 QAWYHGAIPRSEVQ-ELLKCSGDFLVRESQGKQ-EYVLSV-----LWDGQP----RHFII 217 Query 508 EQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGA 567 + D + LEG G FP++ L L QP + I++ A Sbjct 218 QAADNLYRLEGDG--FPTIPLLIDHLLQS----------------QQPITRKSGIVLTRA 259 Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 + ++ +++ +G+G V+ GRLR + Sbjct 260 VLKDK---------WVLNHEDVLLGERIGRGNFGEVFSGRLRADN--------------- 295 Query 628 VPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 V +K + ++ F + A ++ Q +H ++ + GVC + +V Sbjct 296 ---------TPVAVKSCRETLPPELKAKFLQEARILKQYNHPNIVRLIGVCTQKQPIYIV 346 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 E V+ G +LR + H+ M + + + A+ + YLE+K+ +H ++ RN L+ Sbjct 347 MELVQGGDFLSFLRSKGPHLKMKELIKMMENAAAGMEYLESKHCIHRDLAARNCLVTEKN 406 Query 747 LAEGTSPFIKLSDPGVGL----GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGF 800 +K+SD G+ G + +++IP W APE L G S+ D W F Sbjct 407 -------TLKISDFGMSRQEEDGVYASTGGMKQIPVKWTAPEALNYG--RYSSESDVWSF 457 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPS 858 G L E G P + S + ++ RL PE + L +C Y+P +RPS Sbjct 458 GILLWEAFSLGAVPYANLSNQQTREAIEQGVRLEPPEQCPEDVYRLMQRCWEYDPRRRPS 517 Query 859 FRTILRDLTRLQPHNL 874 F + +DL ++ + Sbjct 518 FGAVHQDLIAIRKRHR 533 Score = 273 bits (697), Expect = 7e-79, Method: Composition-based stats. Identities = 91/331 (27%), Positives = 152/331 (46%), Gaps = 23/331 (7%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 E P+ ++ L + Q V + D V + + +G G+F Sbjct 224 YRLEGDGFPTIPLLIDHLLQSQQPITRKSGIVLTRAVLKDKWVLNHEDVLLGERIGRGNF 283 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968 G+V N VAVK+ + P+ ++ + QE IL+ H +I++ G C Sbjct 284 GEVFSGRLRADN----TPVAVKSCRETLPPELKAKFLQEARILKQYNHPNIVRLIGVCTQ 339 Query 969 QGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 + + + +VME V G +L + + +L+ + GM YL ++H IHRDLAA Sbjct 340 K--QPIYIVMELVQGGDFLSFLRSKGPHLKMKELIKMMENAAAGMEYLESKHCIHRDLAA 397 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RN L+ +KI DFG+++ +G Y PV W APE L ++ SDVWS Sbjct 398 RNCLVTEKNTLKISDFGMSRQEEDGV-YASTGGMKQIPVKWTAPEALNYGRYSSESDVWS 456 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 FG+ L+E + L + ++ + E +E+G RL P++CP +VY Sbjct 457 FGILLWEAFS--------------LGAVPYANLSNQQTREAIEQGVRLEPPEQCPEDVYR 502 Query 1147 LMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 LM+ CWE + RP+F + L + ++++ Sbjct 503 LMQRCWEYDPRRRPSFGAVHQDLIAIRKRHR 533 >sp|O13146|EPHA3_DANRE Ephrin type-A receptor 3 OS=Danio rerio OX=7955 GN=epha3 PE=1 SV=1 Length=981 Score = 295 bits (754), Expect = 1e-82, Method: Composition-based stats. Identities = 90/334 (27%), Positives = 154/334 (46%), Gaps = 24/334 (7%) Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR-----YLKKI 900 +C + Q P + R++ + + + + ++ Sbjct 570 RRCGYIKAKQDPEEEKMQFQHGRVKLPETRTYIHPHTYEDPNQAVRDFAKEIEVSNIRIE 629 Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 R +G G FG+V + + VA+K+LKA R + E I+ H +II Sbjct 630 RVIGAGEFGEVCSGRLRLPSKREIQ-VAIKSLKAGYSEHQRRDFLSEASIMGQFDHPNII 688 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018 + +G K + +V EY+ GSL +L +H + QLL + I GM YL + Sbjct 689 RLEGVVTRC--KPVMIVTEYMENGSLDTFLKKHDGQFTVIQLLGMLRGIAAGMQYLSEMN 746 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 Y+HRDLAARN+L++ + + K+ DFGL++ + + E G P+ W APE + KF Sbjct 747 YVHRDLAARNILVNRNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAITYRKF 806 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 ASDVWS+G+ ++E++++ + +M+ + + ++ G RLP P Sbjct 807 TSASDVWSYGIVMWEVISYGER--------------PYWEMSNQDVIKAVDEGYRLPAPM 852 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 CP ++ LM +CWE S RP F ++ L + Sbjct 853 DCPVVLHQLMLDCWEKNRSDRPKFGQIVNTLDRL 886 Score = 275 bits (704), Expect = 5e-76, Method: Composition-based stats. Identities = 79/341 (23%), Positives = 129/341 (38%), Gaps = 42/341 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 ++ I +G G V GRLR+ +E++V + Sbjct 619 KEIEVSNIRIERVIGAGEFGEVCSGRLRLPSK---------------------REIQVAI 657 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV R ++VTEY+E+G LD +L+ Sbjct 658 KSLKAGYSEHQRRDFLSEASIMGQFDHPNIIRLEGVVTRCKPVMIVTEYMENGSLDTFLK 717 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL N VH ++ RNIL+ R + K+SD Sbjct 718 KHDGQFTVIQLLGMLRGIAAGMQYLSEMNYVHRDLAARNILVNR-------NLVCKVSDF 770 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E I W APE + ++A D W +G + E+ GE Sbjct 771 GLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIT--YRKFTSASDVWSYGIVMWEVISYGER 828 Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + +RLP CP L L C + RP F I+ L RL Sbjct 829 PYWEMSNQDVIKAVDEGYRLPAPMDCPVVLHQLMLDCWEKNRSDRPKFGQIVNTLDRLIR 888 Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIR--DLGEGHFGK 910 + + N T + + G + + Sbjct 889 NPSSLKQLANSAVWEDPVTPEAAVNTVEDWLDLIKMGQYKE 929 >sp|P29319|EPHA3_MOUSE Ephrin type-A receptor 3 OS=Mus musculus OX=10090 GN=Epha3 PE=1 SV=1 Length=983 Score = 295 bits (754), Expect = 1e-82, Method: Composition-based stats. Identities = 84/306 (27%), Positives = 143/306 (47%), Gaps = 19/306 (6%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 L+ + + + + +G G FG+V + VA Sbjct 593 LRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKE-ISVA 651 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK + R + E I+ H +II+ +G + +V EY+ GSL Sbjct 652 IKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPE--MIVTEYMENGSLDS 709 Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 +L +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL++ Sbjct 710 FLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSR 769 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 + + E G P+ W +PE + KF ASDVWS+G+ L+E++++ + Sbjct 770 VLEDDPEAAYTTRGGKIPIRWTSPEAMSYRKFTSASDVWSYGIVLWEVMSYGER------ 823 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 QM+ + + ++ RLP P CP +Y LM +CW+ + + RP FE ++ Sbjct 824 --------PYSQMSNQDVIKAVDERYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIV 875 Query 1167 PILKTV 1172 IL + Sbjct 876 SILDKL 881 Score = 269 bits (687), Expect = 7e-74, Method: Composition-based stats. Identities = 74/302 (25%), Positives = 122/302 (40%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D I+ +G G V GRL++ +E+ V + Sbjct 614 KELDATNISIDKVVGAGEFGEVCSGRLKLPSK---------------------KEISVAI 652 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + ++VTEY+E+G LD +LR Sbjct 653 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPEMIVTEYMENGSLDSFLR 712 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + + + + + +AS + YL + VH ++ RNIL+ ++ K+SD Sbjct 713 KHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILIN-------SNLVCKVSDF 765 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E I W +PE + ++A D W +G L E+ GE Sbjct 766 GLSRVLEDDPEAAYTTRGGKIPIRWTSPEAMS--YRKFTSASDVWSYGIVLWEVMSYGER 823 Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + ++RLP P CP L L C + RP F I+ L +L Sbjct 824 PYSQMSNQDVIKAVDERYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIR 883 Query 872 HN 873 + Sbjct 884 NP 885 >sp|Q4JIM5|ABL2_MOUSE Tyrosine-protein kinase ABL2 OS=Mus musculus OX=10090 GN=Abl2 PE=1 SV=1 Length=1182 Score = 297 bits (760), Expect = 2e-82, Method: Composition-based stats. Identities = 96/436 (22%), Positives = 158/436 (36%), Gaps = 70/436 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 HGP+ + L +G +L+ S S P +L +++ R+ Sbjct 169 EKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEG---------RVYH 219 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + I + V F ++ EL A +L Sbjct 220 YRINTTTDSKVYVTAESRFSTLAELVHH---HSTVADGLVTTLHYPAPKC---------- 266 Query 565 RGARASPRTLNLSQL-SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 P +S + +++ +IT LG G VY G + Sbjct 267 ----NKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYS----------- 311 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 L V +K ++ F + A++M ++ H +L + GVC P Sbjct 312 -------------LTVAVKTFKEDTMEV-EEFLKEAAVMKEIKHPNLVQLLGVCTLEPPF 357 Query 684 IMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +VTEY+ +G L +LR R V + +A Q++SA+ YLE KN +H ++ RN L+ Sbjct 358 YIVTEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLV 417 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDK 797 G + +K++D G+ I W APE L N+ S D Sbjct 418 -------GENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLA--YNTFSIKSDV 468 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855 W FG L EI G +P S+ ++ +R+ PE P++ L C + P Sbjct 469 WAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPAD 528 Query 856 RPSFRTILRDLTRLQP 871 RPSF + + Sbjct 529 RPSFAETHQAFETMFH 544 Score = 289 bits (739), Expect = 1e-79, Method: Composition-based stats. Identities = 93/307 (30%), Positives = 147/307 (48%), Gaps = 27/307 (9%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 P + TV SP D + + LG G +G+V + + + VA Sbjct 260 HYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSL----TVA 315 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 VK K D + +E +++ + H ++++ G C E +V EY+P G+L D Sbjct 316 VKTFKEDT--MEVEEFLKEAAVMKEIKHPNLVQLLGVCT--LEPPFYIVTEYMPYGNLLD 371 Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 YL R + LL A QI M YL +++IHRDLAARN L+ + +VK+ DFGL+ Sbjct 372 YLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLS 431 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + Y P+ W APE L F SDVW+FGV L+E+ T+ S Sbjct 432 RLMT--GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMS----- 484 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + ++ +LLE+G R+ +P+ CP +VY LM+ CW+ + RP+F Sbjct 485 ---------PYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAET 535 Query 1166 IPILKTV 1172 +T+ Sbjct 536 HQAFETM 542 >sp|P08103|HCK_MOUSE Tyrosine-protein kinase HCK OS=Mus musculus OX=10090 GN=Hck PE=1 SV=4 Length=524 Score = 282 bits (722), Expect = 2e-82, Method: Composition-based stats. Identities = 82/447 (18%), Positives = 149/447 (33%), Gaps = 71/447 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502 + + + L G ++I S + L+V + Sbjct 138 ETEEWFFKGISRKDAERHLLAPGNMLGSFMIRDSETTKGSYSLSVRDFDP----QHGDTV 193 Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562 + + I D +F S++EL + C L C+ Sbjct 194 KHYKIRTLDSGGFYISPRSTFSSLQELVLHYKKGK---DGLCQKLSVPCV---------- 240 Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 SP+ + + ++ + LG G V+ Sbjct 241 -------SPKPQKPWEKDAWEIPRESLQMEKKLGAGQFGEVWMAT--------------- 278 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 + +V +K + P + AF A+LM + H L +H V + Sbjct 279 ----------YNKHTKVAVKTMKPGSMSV-EAFLAEANLMKSLQHDKLVKLHAVVSQ-EP 326 Query 683 NIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 +VTE++ G L +L+ E G P+ + + Q++ ++++E +N +H ++ NIL Sbjct 327 IFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQISEGMAFIEQRNYIHRDLRAANIL 386 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMD 796 ++ S K++D G+ E I W APE + G S + D Sbjct 387 VS-------ASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFG--SFTIKSD 437 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854 W FG L+EI G P S E + +R+ P+ +L + +C P Sbjct 438 VWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNCPEELYNIMIRCWKNRPE 497 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVN 881 +RP+F I L + Sbjct 498 ERPTFEYIQSVLDDFYTATESQYQQQP 524 Score = 280 bits (717), Expect = 1e-81, Method: Composition-based stats. Identities = 95/293 (32%), Positives = 147/293 (50%), Gaps = 29/293 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + L+ + LG G FG+V + Y N T VAVK +K G + E + Sbjct 253 WEIPRESLQMEKKLGAGQFGEVWMATY---NKHT--KVAVKTMKP--GSMSVEAFLAEAN 305 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQ 1006 ++++L H+ ++K ++ + +V E++ GSL D+L L +L+ F+ Q Sbjct 306 LMKSLQHDKLVKLHAVV---SQEPIFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQ 362 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I EGMA++ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ Sbjct 363 ISEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNE--YTAREGAKFPIK 420 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE + F SDVWSFG+ L E++T+ I M+ + Sbjct 421 WTAPEAINFGSFTIKSDVWSFGILLMEIVTYGR--------------IPYPGMSNPEVIR 466 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 LE G R+PRPD CP E+Y++M CW+ RPTFE + +L + + Q Sbjct 467 ALEHGYRMPRPDNCPEELYNIMIRCWKNRPEERPTFEYIQSVLDDFYTATESQ 519 >sp|P16277|BLK_MOUSE Tyrosine-protein kinase Blk OS=Mus musculus OX=10090 GN=Blk PE=1 SV=4 Length=499 Score = 281 bits (719), Expect = 2e-82, Method: Composition-based stats. Identities = 85/437 (19%), Positives = 159/437 (36%), Gaps = 73/437 (17%) Query 438 VAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 VAP + + + + +L + G +LI S S+ L+V + Sbjct 107 VAPVETLE-VEKWFFRTISRKDAERQLLAPMNKAGSFLIRESESNKGAFSLSVKDITTQG 165 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 + ++ ++R D +FP+++ L C L C+ Sbjct 166 EVVKHYKIR-----SLDNGGYYISPRITFPTLQALVQHYSKKG---DGLCQKLTLPCV-- 215 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 + NL + ++ + + LG G V+ G + Sbjct 216 ---------------NLAPKNLWAQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNN--- 257 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 ++V +K L AF A++M + H L ++ Sbjct 258 ----------------------MKVAIKTLKEGTMSP-EAFLGEANVMKTLQHERLVRLY 294 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHG 733 V R +VTEY+ G L +L+ + G + + + ++ Q+A ++Y+E N +H Sbjct 295 AVVTR-EPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMAYIERMNSIHR 353 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGAN 789 ++ NIL++ + K++D G+ ++E I W APE + G Sbjct 354 DLRAANILVSE-------TLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGV- 405 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLA-TLTS 846 + D W FG L+EI G P S E + +R+P P P+L + + Sbjct 406 -FTIKADVWSFGVLLMEIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPELYNDIIT 464 Query 847 QCLTYEPTQRPSFRTIL 863 +C P +RP+F + Sbjct 465 ECWRGRPEERPTFEFLQ 481 Score = 273 bits (699), Expect = 1e-79, Method: Composition-based stats. Identities = 92/297 (31%), Positives = 141/297 (47%), Gaps = 31/297 (10%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 D ++ LK +R LG G FG+V + Y VA+K LK G + Sbjct 225 QDEWEIPRQSLKLVRKLGSGQFGEVWMGYYK-----NNMKVAIKTLKE--GTMSPEAFLG 277 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLF 1003 E ++++TL HE +++ + + +V EY+ G L D+L + L +L+ Sbjct 278 EANVMKTLQHERLVRLYAVV---TREPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDM 334 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 + Q+ EGMAY+ + IHRDL A N+L+ KI DFGLA+ + Y +E Sbjct 335 SAQVAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARII---DSEYTAQEGAKF 391 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 P+ W APE + F +DVWSFGV L E++T+ + M+ Sbjct 392 PIKWTAPEAIHFGVFTIKADVWSFGVLLMEIVTYGR--------------VPYPGMSNPE 437 Query 1124 LTELLERGERLPRPDKCPCEVY-HLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 + LE G R+P P+ CP E+Y ++ CW RPTFE L +L+ + +GQ Sbjct 438 VIRSLEHGYRMPCPETCPPELYNDIITECWRGRPEERPTFEFLQSVLEDFYTATEGQ 494 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens OX=9606 GN=EPHA2 PE=1 SV=2 Length=976 Score = 293 bits (751), Expect = 3e-82, Method: Composition-based stats. Identities = 86/307 (28%), Positives = 147/307 (48%), Gaps = 18/307 (6%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 L+ + + T H + + + +G G FG+V ++ V Sbjct 584 PLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPV 643 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LKA + R + E I+ H +II+ +G K + ++ EY+ G+L Sbjct 644 AIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKY--KPMMIITEYMENGALD 701 Query 988 DYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL+ Sbjct 702 KFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLS 761 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + E G P+ W APE + KF ASDVWSFG+ ++E++T+ + Sbjct 762 RVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGER----- 816 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 +++ + + + G RLP P CP +Y LM CW+ E + RP F ++ Sbjct 817 ---------PYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADI 867 Query 1166 IPILKTV 1172 + IL + Sbjct 868 VSILDKL 874 Score = 268 bits (685), Expect = 1e-73, Method: Composition-based stats. Identities = 76/299 (25%), Positives = 122/299 (41%), Gaps = 39/299 (13%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 + +T+ +G G VY+G L+ +E+ V Sbjct 605 TTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSG--------------------KKEVPVA 644 Query 641 LKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +K L + + F A +M Q SH ++ + GV + +++TEY+E+G LD +L Sbjct 645 IKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFL 704 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R + G + + + + +A+ + YL N N VH ++ RNIL+ ++ K+SD Sbjct 705 REKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVN-------SNLVCKVSD 757 Query 760 PGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 G+ E I W APE + ++A D W FG + E+ GE Sbjct 758 FGLSRVLEDDPEATYTTSGGKIPIRWTAPEAIS--YRKFTSASDVWSFGIVMWEVMTYGE 815 Query 813 APLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 P S E RLP CP + L QC E +RP F I+ L +L Sbjct 816 RPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKL 874 >sp|P42681|TXK_HUMAN Tyrosine-protein kinase TXK OS=Homo sapiens OX=9606 GN=TXK PE=1 SV=3 Length=527 Score = 282 bits (721), Expect = 3e-82, Method: Composition-based stats. Identities = 87/426 (20%), Positives = 159/426 (37%), Gaps = 64/426 (15%) Query 446 SIRDGIHGPLLEPFVQAKLRPE--DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLR 503 I + H + + LR E +G +++ S H ++V ++ ++ Sbjct 146 EIYEWYHRNITRNQAEHLLRQESKEGAFIVRDS-RHLGSYTISVFMGARRSTEAA---IK 201 Query 504 KFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLII 563 + I++ D +F S+ EL Q A LR + Sbjct 202 HYQIKKNDSGQWYVAERHAFQSIPELIWYHQHN---AAGLMTRLRYP------------V 246 Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 P T S +D E+ + +G G V+ G R Sbjct 247 GLMGSCLPATAGFSY-EKWEIDPSELAFIKEIGSGQFGVVHLGEWR-------------- 291 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 ++V +K ++ F E A +M ++SH+ L ++GVC++ Sbjct 292 -----------SHIQVAIKAINEGSMS-EEDFIEEAKVMMKLSHSKLVQLYGVCIQRKPL 339 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 +VTE++E+G L +LR +G + + V Q + + YLE +H ++ RN L++ Sbjct 340 YIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVS 399 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKW 798 ++ +K+SD G+ L E I W PE N S+ D W Sbjct 400 -------STCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFL--FNKYSSKSDVW 450 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 FG + E+ +G+ P +++S + RL P + + + C +P R Sbjct 451 SFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGR 510 Query 857 PSFRTI 862 P+F + Sbjct 511 PTFAEL 516 Score = 256 bits (655), Expect = 3e-73, Method: Composition-based stats. Identities = 89/302 (29%), Positives = 134/302 (44%), Gaps = 27/302 (9%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 + + L I+++G G FG V L + + VA+KA+ Sbjct 249 MGSCLPATAGFSYEKWEIDPSELAFIKEIGSGQFGVVHLGEWR-----SHIQVAIKAINE 303 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994 G + +E ++ L H +++ G C + K L +V E++ G L +YL + Sbjct 304 --GSMSEEDFIEEAKVMMKLSHSKLVQLYGVCIQR--KPLYIVTEFMENGCLLNYLRENK 359 Query 995 IGL--AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 L LL Q ICEGM YL YIHRDLAARN L+ + +VKI DFG+ + V + Sbjct 360 GKLRKEMLLSVCQDICEGMEYLERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDE 419 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 Y P+ W PE K+ SDVWSFGV ++E+ T Sbjct 420 --YVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGK------------- 464 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + + L++ E + G RL RP P +Y +M +CW + RPTF L+ + + Sbjct 465 -MPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLRAVTEI 523 Query 1173 HE 1174 E Sbjct 524 AE 525 >sp|P07332|FES_HUMAN Tyrosine-protein kinase Fes/Fps OS=Homo sapiens OX=9606 GN=FES PE=1 SV=3 Length=822 Score = 290 bits (741), Expect = 4e-82, Method: Composition-based stats. Identities = 107/451 (24%), Positives = 174/451 (39%), Gaps = 85/451 (19%) Query 434 LCHEVAPPRLVMSIRDGIHGPLLEPFVQ-AKLRPEDGLYLIHWSTSHPYRLILTVAQRSQ 492 L EV P + HG + P + A+L G +L+ S +L+V Sbjct 447 LIPEVQKPL---HEQLWYHGAI--PRAEVAELLVHSGDFLVRESQGKQ-EYVLSV----- 495 Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL 552 DG+ R F I+ D + LEG G FPS+ L L Sbjct 496 LWDGLP----RHFIIQSLDNLYRLEGEG--FPSIPLLIDHLLS----------------T 533 Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 QP + +++ A + ++ +++ +G+G V+ GRLR + Sbjct 534 QQPLTKKSGVVLHRAVPKDK---------WVLNHEDLVLGEQIGRGNFGEVFSGRLRADN 584 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLA 671 V +K + D+ F + A ++ Q SH ++ Sbjct 585 ------------------------TLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIV 620 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 + GVC + +V E V+ G +LR E + + + + A+ + YLE+K + Sbjct 621 RLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCI 680 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLP 785 H ++ RN L+ + +K+SD G+ + W APE L Sbjct 681 HRDLAARNCLVTEKNV-------LKISDFGMSREEADGVYAASGGLRQVPVKWTAPEALN 733 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LAT 843 G S+ D W FG L E G +P + S + F ++ RLP P CP + Sbjct 734 YG--RYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFR 791 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 L QC YEP QRPSF TI ++L ++ + Sbjct 792 LMEQCWAYEPGQRPSFSTIYQELQSIRKRHR 822 Score = 273 bits (698), Expect = 2e-76, Method: Composition-based stats. Identities = 93/331 (28%), Positives = 148/331 (45%), Gaps = 23/331 (7%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 E PS ++ L Q V + D V + L +G G+F Sbjct 513 YRLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVPKDKWVLNHEDLVLGEQIGRGNF 572 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968 G+V N +VAVK+ + P ++ + QE IL+ H +I++ G C Sbjct 573 GEVFSGRLRADN----TLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQ 628 Query 969 QGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 + + + +VME V G +L + + LL GM YL ++ IHRDLAA Sbjct 629 K--QPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAA 686 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RN L+ ++KI DFG+++ +G Y PV W APE L ++ SDVWS Sbjct 687 RNCLVTEKNVLKISDFGMSREEADGV-YAASGGLRQVPVKWTAPEALNYGRYSSESDVWS 745 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 FG+ L+E + L ++ + E +E+G RLP P+ CP V+ Sbjct 746 FGILLWETFS--------------LGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFR 791 Query 1147 LMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 LM+ CW E RP+F + L+++ ++++ Sbjct 792 LMEQCWAYEPGQRPSFSTIYQELQSIRKRHR 822 >sp|P50545|HCK_RAT Tyrosine-protein kinase HCK OS=Rattus norvegicus OX=10116 GN=Hck PE=1 SV=4 Length=524 Score = 281 bits (720), Expect = 4e-82, Method: Composition-based stats. Identities = 82/447 (18%), Positives = 150/447 (34%), Gaps = 71/447 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPED---GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRL 502 + + + L G ++I S + L+V + Sbjct 138 ETEEWFFKGISRKDAERHLLAPGNMLGSFMIRDSETTKGSYSLSVRDFDP----QHGDTV 193 Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562 + + I D +F S++EL + C L C+ Sbjct 194 KHYKIRTLDSGGFYISPRSTFSSLQELVVHYKKGK---DGLCQKLSVPCV---------- 240 Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 SP+ + + ++ + LG G V+ Sbjct 241 -------SPKPQKPWEKDAWEIPRESLQMEKKLGAGQFGEVWMAT--------------- 278 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 + +V +K + P + AF A+LM + H L +H V + Sbjct 279 ----------YNKHTKVAVKTMKPGSMSV-EAFLAEANLMKTLQHDKLVKLHAVVSQ-EP 326 Query 683 NIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 +VTE++ G L +L+ E G P+ + + Q++ ++++E +N +H ++ NIL Sbjct 327 IFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQISEGMAFIEQRNYIHRDLRAANIL 386 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMD 796 ++ S K++D G+ E I W APE + G S + D Sbjct 387 VS-------ASLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFG--SFTIKSD 437 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854 W FG L+EI G P S E + +R+ P+ +L ++ +C P Sbjct 438 VWSFGILLMEIVTYGRIPYPGMSNPEVIRALEHGYRMPRPDNCPEELYSIMIRCWKNRPE 497 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVN 881 +RP+F I L + Sbjct 498 ERPTFEYIQSVLDDFYTATESQYQQQP 524 Score = 279 bits (714), Expect = 2e-81, Method: Composition-based stats. Identities = 96/293 (33%), Positives = 146/293 (50%), Gaps = 29/293 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + L+ + LG G FG+V + Y N T VAVK +K G + E + Sbjct 253 WEIPRESLQMEKKLGAGQFGEVWMATY---NKHT--KVAVKTMKP--GSMSVEAFLAEAN 305 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQ 1006 +++TL H+ ++K ++ + +V E++ GSL D+L L +L+ F+ Q Sbjct 306 LMKTLQHDKLVKLHAVV---SQEPIFIVTEFMAKGSLLDFLKSEEGSKQPLPKLIDFSAQ 362 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I EGMA++ ++YIHRDL A N+L+ + KI DFGLA+ + + Y RE P+ Sbjct 363 ISEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARIIEDNE--YTAREGAKFPIK 420 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE + F SDVWSFG+ L E++T+ I M+ + Sbjct 421 WTAPEAINFGSFTIKSDVWSFGILLMEIVTYGR--------------IPYPGMSNPEVIR 466 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 LE G R+PRPD CP E+Y +M CW+ RPTFE + +L + + Q Sbjct 467 ALEHGYRMPRPDNCPEELYSIMIRCWKNRPEERPTFEYIQSVLDDFYTATESQ 519 >sp|P42682|TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus musculus OX=10090 GN=Txk PE=1 SV=1 Length=527 Score = 281 bits (719), Expect = 6e-82, Method: Composition-based stats. Identities = 93/435 (21%), Positives = 166/435 (38%), Gaps = 68/435 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRPE--DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLR-- 501 I + H + + LR E +G +++ S H ++V R + + Sbjct 146 EIYEWYHKNITRNQTERLLRQEAKEGAFIVRDS-RHLGSYTISVFTR-----ARRHTQSS 199 Query 502 LRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNL 561 ++ + I++ D FPSV EL Q A LR Sbjct 200 IKHYQIKKNDSGQWYITERHLFPSVPELIQYHQYN---AAGLISRLRYP----------- 245 Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 I P T S +D E+ + +G G V+ G R Sbjct 246 -IGLLGSCLPATSGFSY-EKWEIDPSELAFVKEIGSGQFGVVHLGEWRA----------- 292 Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 + V +K ++ F E A +M ++SH+ L ++GVC++ Sbjct 293 --------------HIPVAIKAINEGSMS-EEDFIEEAKVMMKLSHSRLVQLYGVCIQQK 337 Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 +VTE++E+G L +LR +G + A + + Q + ++YLE +H ++ RN L Sbjct 338 PLYIVTEFMENGCLLDYLRERKGQLQKALLLSMCQDICEGMAYLERSCYIHRDLAARNCL 397 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMD 796 ++ ++ +K+SD G+ L E + W PE N S+ D Sbjct 398 VS-------SACVVKISDFGMARYVLDDEYISSSGAKFPVKWCPPEVFH--FNKYSSKSD 448 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854 W FG + E+ +G+ P +++S + + RL P + + + C P Sbjct 449 VWSFGVLMWEVFTEGKMPFENKSNLQVVEAISQGFRLYRPHLAPMTIYRVMYSCWHESPK 508 Query 855 QRPSFRTILRDLTRL 869 RP+F +L+ LT + Sbjct 509 GRPTFAELLQVLTEI 523 Score = 263 bits (672), Expect = 1e-75, Method: Composition-based stats. Identities = 94/299 (31%), Positives = 136/299 (45%), Gaps = 27/299 (9%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + + L ++++G G FG V L + VA+KA+ G Sbjct 252 CLPATSGFSYEKWEIDPSELAFVKEIGSGQFGVVHLGEWRAH-----IPVAIKAINE--G 304 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL 997 + +E ++ L H +++ G C Q K L +V E++ G L DYL L Sbjct 305 SMSEEDFIEEAKVMMKLSHSRLVQLYGVCIQQ--KPLYIVTEFMENGCLLDYLRERKGQL 362 Query 998 AQ--LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + LL Q ICEGMAYL YIHRDLAARN L+ + +VKI DFG+A+ V + Y Sbjct 363 QKALLLSMCQDICEGMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARYVLDDE--Y 420 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 PV W PE K+ SDVWSFGV ++E+ T + Sbjct 421 ISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGK--------------MP 466 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + L++ E + +G RL RP P +Y +M +CW RPTF L+ +L + E Sbjct 467 FENKSNLQVVEAISQGFRLYRPHLAPMTIYRVMYSCWHESPKGRPTFAELLQVLTEIAE 525 >sp|Q91736|EPB1B_XENLA Ephrin type-B receptor 1-B (Fragment) OS=Xenopus laevis OX=8355 GN=ephb1-b PE=1 SV=1 Length=902 Score = 291 bits (744), Expect = 6e-82, Method: Composition-based stats. Identities = 79/308 (26%), Positives = 146/308 (47%), Gaps = 21/308 (7%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 ++ + ++ ++K +G G FG+V + VA Sbjct 509 MKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPSKRE-ISVA 567 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LKA + R + E I+ H +II+ +G + + ++ E++ G+L Sbjct 568 IKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGALDS 625 Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 +L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++ Sbjct 626 FLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 685 Query 1047 AVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 + + Y G PV W APE ++ KF ASDVWS+G+ ++E++++ + Sbjct 686 YLQDDTSDPTYTSSLGGKIPVRWTAPEAIRYRKFTSASDVWSYGIVMWEVMSYGER---- 741 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 M+ + +E+ RLP P CP ++ LM +CW+ + + RP F Sbjct 742 ----------PYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFGE 791 Query 1165 LIPILKTV 1172 ++ L + Sbjct 792 IVNTLDKM 799 Score = 277 bits (709), Expect = 3e-77, Method: Composition-based stats. Identities = 76/355 (21%), Positives = 136/355 (38%), Gaps = 42/355 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G VY+GRL++ +E+ V + Sbjct 530 KEIDVSFVKIEEVIGAGEFGEVYKGRLKLPSK---------------------REISVAI 568 Query 642 KVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L F AS+M Q H ++ + GV + +++TE++E+G LD +LR Sbjct 569 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 628 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD Sbjct 629 QNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 681 Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ +IP W APE + ++A D W +G + E+ G Sbjct 682 GLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIR--YRKFTSASDVWSYGIVMWEVMSYG 739 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P S + + ++ +RLP P CP L L C + RP F I+ L ++ Sbjct 740 ERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFGEIVNTLDKM 799 Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 + + + S P + + + + Y +G Sbjct 800 IRNPASLKTVATIPAVPSQPLLDRSIPDISAFTSVDDWLSAIKMGQYRDNFLSSG 854 >sp|Q91694|EPA4B_XENLA Ephrin type-A receptor 4-B OS=Xenopus laevis OX=8355 GN=epha4-b PE=2 SV=1 Length=985 Score = 292 bits (747), Expect = 9e-82, Method: Composition-based stats. Identities = 83/331 (25%), Positives = 148/331 (45%), Gaps = 19/331 (6%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 + S+ + + ++ + + +K + + Sbjct 567 VISRRRSKYSKAKQEADEEKHLNQGVKTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVI 626 Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963 G G FG+V VA+K LKA + R + E I+ H +II + Sbjct 627 GVGEFGEVCSGRLKVPGKRE-IYVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLE 685 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G K + ++ EY+ GSL +L ++ + QL+ + I GM YL Y+H Sbjct 686 GVVTKC--KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVH 743 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RDLAARN+L++++ + K+ DFG+++ + + E G P+ W APE + KF A Sbjct 744 RDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSA 803 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 SDVWS+G+ ++E++++ + M+ + + +E G RLP P CP Sbjct 804 SDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVIKAIEEGYRLPPPMDCP 849 Query 1142 CEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 ++ LM +CW+ + S RP F ++ +L + Sbjct 850 IALHQLMLDCWQKDRSDRPKFGQIVSMLDKL 880 Score = 269 bits (688), Expect = 6e-74, Method: Composition-based stats. Identities = 76/302 (25%), Positives = 124/302 (41%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D I +G G V GRL+V G +E+ V + Sbjct 613 KEIDASCIKIEKVIGVGEFGEVCSGRLKVPGK---------------------REIYVAI 651 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + D F AS+M Q H ++ + GV + +++TEY+E+G LD +LR Sbjct 652 KTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLR 711 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + + S + YL + + VH ++ RNIL+ ++ K+SD Sbjct 712 KNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVN-------SNLVCKVSDF 764 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E I W APE + ++A D W +G + E+ GE Sbjct 765 GMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER 822 Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + + +RLP P CP L L C + + RP F I+ L +L Sbjct 823 PYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKDRSDRPKFGQIVSMLDKLIR 882 Query 872 HN 873 + Sbjct 883 NP 884 >sp|Q91845|EPA4A_XENLA Ephrin type-A receptor 4-A OS=Xenopus laevis OX=8355 GN=epha4-a PE=2 SV=1 Length=986 Score = 291 bits (746), Expect = 1e-81, Method: Composition-based stats. Identities = 84/331 (25%), Positives = 148/331 (45%), Gaps = 19/331 (6%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 + S+ + + ++ + + +K + + Sbjct 567 VISRRRSKYSKAKQEADEEKHLNQGVKTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVI 626 Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963 G G FG+V VA+K LKA + R + E I+ H +II + Sbjct 627 GVGEFGEVCSGRLKVPGKRE-IYVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLE 685 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G K + ++ EY+ GSL +L ++ + QL+ + I GM YL Y+H Sbjct 686 GVVTKC--KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGILRGIGSGMKYLSDMSYVH 743 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RDLAARN+L++++ + K+ DFG+++ + + E G P+ W APE + KF A Sbjct 744 RDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSA 803 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 SDVWS+G+ ++E++++ + M+ + + +E G RLP P CP Sbjct 804 SDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVIKAIEEGYRLPPPMDCP 849 Query 1142 CEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 ++ LM +CW+ E S RP F ++ +L + Sbjct 850 IALHQLMLDCWQKERSDRPKFGQIVSMLDKL 880 Score = 270 bits (689), Expect = 5e-74, Method: Composition-based stats. Identities = 77/302 (25%), Positives = 124/302 (41%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D I +G G V GRL+V G +E+ V + Sbjct 613 KEIDASCIKIEKVIGVGEFGEVCSGRLKVPGK---------------------REIYVAI 651 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + D F AS+M Q H ++ + GV + +++TEY+E+G LD +LR Sbjct 652 KTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLR 711 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + + S + YL + + VH ++ RNIL+ ++ K+SD Sbjct 712 KNDGRFTVIQLVGILRGIGSGMKYLSDMSYVHRDLAARNILVN-------SNLVCKVSDF 764 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E I W APE + ++A D W +G + E+ GE Sbjct 765 GMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER 822 Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + + +RLP P CP L L C E + RP F I+ L +L Sbjct 823 PYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVSMLDKLIR 882 Query 872 HN 873 + Sbjct 883 NP 884 >sp|P54763|EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus musculus OX=10090 GN=Ephb2 PE=1 SV=3 Length=986 Score = 291 bits (746), Expect = 1e-81, Method: Composition-based stats. Identities = 81/325 (25%), Positives = 147/325 (45%), Gaps = 21/325 (6%) Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911 E T + T ++ + ++ +K + +G G FG+V Sbjct 576 EYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEV 635 Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 VA+K LK+ + R + E I+ H ++I +G Sbjct 636 CSGHLKLPGKRE-IFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKST- 693 Query 972 KSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029 + ++ E++ GSL +L ++ + QL+ + I GM YL +Y+HRDLAARN+ Sbjct 694 -PVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNI 752 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 L++++ + K+ DFGL++ + + Y G P+ W APE ++ KF ASDVWS+ Sbjct 753 LVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSY 812 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 G+ ++E++++ + MT + +E+ RLP P CP ++ L Sbjct 813 GIVMWEVMSYGER--------------PYWDMTNQDVINAIEQDYRLPPPMDCPSALHQL 858 Query 1148 MKNCWETEASFRPTFENLIPILKTV 1172 M +CW+ + + RP F ++ L + Sbjct 859 MLDCWQKDRNHRPKFGQIVNTLDKM 883 Score = 268 bits (685), Expect = 1e-73, Method: Composition-based stats. Identities = 70/304 (23%), Positives = 125/304 (41%), Gaps = 42/304 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G V G L++ G +E+ V + Sbjct 614 KEIDISCVKIEQVIGAGEFGEVCSGHLKLPGK---------------------REIFVAI 652 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + +++TE++E+G LD +LR Sbjct 653 KTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLR 712 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL + N VH ++ RNIL+ ++ K+SD Sbjct 713 QNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVN-------SNLVCKVSDF 765 Query 761 GVGL---GALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ S I W APE + ++A D W +G + E+ G Sbjct 766 GLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYG 823 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P + + + ++ +RLP P CP L L C + RP F I+ L ++ Sbjct 824 ERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 883 Query 870 QPHN 873 + Sbjct 884 IRNP 887 >sp|P21802|FGFR2_HUMAN Fibroblast growth factor receptor 2 OS=Homo sapiens OX=9606 GN=FGFR2 PE=1 SV=1 Length=821 Score = 288 bits (737), Expect = 1e-81, Method: Composition-based stats. Identities = 106/343 (31%), Positives = 159/343 (46%), Gaps = 53/343 (15%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCG 937 + P F + L + LGEG FG+V + + + VAVK LK D Sbjct 465 EYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDAT 524 Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990 + S E+++++ + H++II G C G L +++EY G+LR+YL Sbjct 525 EKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPP 582 Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P + L+ Q+ GM YL +Q IHRDLAARNVL+ + ++KI Sbjct 583 GMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKI 642 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV ++E+ T Sbjct 643 ADFGLARDI-NNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT--- 698 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L G + V L +LL+ G R+ +P C E+Y +M++CW S R Sbjct 699 -----------LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQR 747 Query 1160 PTFENLIPILKTV---------------HEKYQGQAPSVFSVC 1187 PTF+ L+ L + E+Y P S C Sbjct 748 PTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSC 790 Score = 234 bits (596), Expect = 7e-63, Method: Composition-based stats. Identities = 65/323 (20%), Positives = 117/323 (36%), Gaps = 51/323 (16%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 L + + ++T LG+G V + E + Sbjct 464 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQV-----------------VMAEAVGIDKD 506 Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689 + + V +K+L + L +M + H ++ + G C + ++ EY Sbjct 507 KPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 566 Query 690 VEHGPLDVWLRRER----------GHVPMAW-----KMVVAQQLASALSYLENKNLVHGN 734 G L +LR R VP + QLA + YL ++ +H + Sbjct 567 ASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD 626 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788 + RN+L+ + +K++D G+ ++ R+P W+APE L Sbjct 627 LAARNVLVTENNV-------MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRV 679 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846 + D W FG + EI G +P E + HR+ P +L + Sbjct 680 --YTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMR 737 Query 847 QCLTYEPTQRPSFRTILRDLTRL 869 C P+QRP+F+ ++ DL R+ Sbjct 738 DCWHAVPSQRPTFKQLVEDLDRI 760 >sp|Q1KL86|EPHA2_MACFA Ephrin type-A receptor 2 OS=Macaca fascicularis OX=9541 GN=EPHA2 PE=2 SV=1 Length=976 Score = 291 bits (746), Expect = 1e-81, Method: Composition-based stats. Identities = 87/329 (26%), Positives = 153/329 (47%), Gaps = 18/329 (5%) Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 + L + + + L L+ + + T H + + + +G Sbjct 562 RKNLRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGA 621 Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGC 965 G FG+V ++ VA+K LKA + R + E I+ H +II+ +G Sbjct 622 GEFGEVYKGTLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGV 681 Query 966 CEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRD 1023 K + ++ E++ G+L +L + QL+ + I GM YL +Y+HRD Sbjct 682 ISKY--KPMMIITEFMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRD 739 Query 1024 LAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASD 1083 LAARN+L++++ + K+ DFGL++ + + E G P+ W APE + KF ASD Sbjct 740 LAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASD 799 Query 1084 VWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE 1143 VWSFG+ ++E++T+ + +++ + + + G RLP P CP Sbjct 800 VWSFGIVMWEVMTYGER--------------PYWELSNHEVMKAINDGFRLPTPMDCPSA 845 Query 1144 VYHLMKNCWETEASFRPTFENLIPILKTV 1172 +Y LM CW+ E + RP F +++ IL + Sbjct 846 IYQLMMQCWQQERARRPKFADIVSILDKL 874 Score = 266 bits (681), Expect = 5e-73, Method: Composition-based stats. Identities = 75/299 (25%), Positives = 122/299 (41%), Gaps = 39/299 (13%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 + +T+ +G G VY+G L+ +E+ V Sbjct 605 TTEIHPSCVTRQKVIGAGEFGEVYKGTLKTSSG--------------------KKEVPVA 644 Query 641 LKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +K L + + F A +M Q SH ++ + GV + +++TE++E+G LD +L Sbjct 645 IKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEFMENGALDKFL 704 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R + G + + + + +A+ + YL N N VH ++ RNIL+ ++ K+SD Sbjct 705 REKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVN-------SNLVCKVSD 757 Query 760 PGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 G+ E I W APE + ++A D W FG + E+ GE Sbjct 758 FGLSRVLEDDPEATYTTSGGKIPIRWTAPEAIS--YRKFTSASDVWSFGIVMWEVMTYGE 815 Query 813 APLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 P S E RLP CP + L QC E +RP F I+ L +L Sbjct 816 RPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKL 874 >sp|P21804|FGFR1_CHICK Fibroblast growth factor receptor 1 OS=Gallus gallus OX=9031 GN=FGFR1 PE=2 SV=1 Length=819 Score = 288 bits (737), Expect = 1e-81, Method: Composition-based stats. Identities = 103/313 (33%), Positives = 153/313 (49%), Gaps = 38/313 (12%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---EMVAVKALKADCG 937 + P + L + LGEG FG+V L + VAVK LK+D Sbjct 460 EYELPEDPRWELPRDRLILGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDAT 519 Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990 + S E+++++ + H++II G C G L +++EY G+LR+YL Sbjct 520 EKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLQARRPP 577 Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI Sbjct 578 GMEYCYNPTRIPEEQLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKI 637 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T Sbjct 638 ADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--- 693 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L G + V L +LL+ G R+ +P C E+Y +M++CW S R Sbjct 694 -----------LGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQR 742 Query 1160 PTFENLIPILKTV 1172 PTF+ L+ L + Sbjct 743 PTFKQLVEDLDRI 755 Score = 235 bits (600), Expect = 2e-63, Method: Composition-based stats. Identities = 63/332 (19%), Positives = 116/332 (35%), Gaps = 51/332 (15%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 L + + + + LG+G V + E + Sbjct 459 SEYELPEDPRWELPRDRLILGKPLGEGCFGQV-----------------VLAEAIGLDKD 501 Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689 + +V +K+L + L +M + H ++ + G C + ++ EY Sbjct 502 KPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 561 Query 690 VEHGPLDVWLRRERG---------------HVPMAWKMVVAQQLASALSYLENKNLVHGN 734 G L +L+ R + + A Q+A + YL +K +H + Sbjct 562 ASKGNLREYLQARRPPGMEYCYNPTRIPEEQLSFKDLVSCAYQVARGMEYLASKKCIHRD 621 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788 + RN+L+ + +K++D G+ ++ R+P W+APE L Sbjct 622 LAARNVLVTEDNV-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRI 674 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846 + D W FG L EI G +P E + HR+ P +L + Sbjct 675 --YTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMR 732 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 C P+QRP+F+ ++ DL R+ Sbjct 733 DCWHAVPSQRPTFKQLVEDLDRIVAMTSNQEY 764 >sp|P18461|FGFR2_CHICK Fibroblast growth factor receptor 2 OS=Gallus gallus OX=9031 GN=FGFR2 PE=2 SV=1 Length=823 Score = 288 bits (737), Expect = 2e-81, Method: Composition-based stats. Identities = 106/343 (31%), Positives = 160/343 (47%), Gaps = 53/343 (15%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCG 937 + P F + L + LGEG FG+V + + + VAVK LK D Sbjct 467 EYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKEAVTVAVKMLKDDAT 526 Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990 + S E+++++ + H++II G C G L +++EY G+LR+YL Sbjct 527 EKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPP 584 Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P + L+ Q+ GM YL +Q IHRDLAARNVL+ + ++KI Sbjct 585 GMEYSFDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKI 644 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV ++E+ T Sbjct 645 ADFGLARDI-NNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT--- 700 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L G + V L +LL+ G R+ +P C E+Y +M++CW+ S R Sbjct 701 -----------LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWQAVPSQR 749 Query 1160 PTFENLIPILKTV---------------HEKYQGQAPSVFSVC 1187 PTF+ L+ L + E+Y P S C Sbjct 750 PTFKQLVEDLDRILTLTTNEEYLDLSGPLEQYSPSYPDTRSSC 792 Score = 233 bits (594), Expect = 1e-62, Method: Composition-based stats. Identities = 65/323 (20%), Positives = 117/323 (36%), Gaps = 51/323 (16%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 L + + ++T LG+G V + E + Sbjct 466 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQV-----------------VMAEAVGIDKD 508 Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689 + + V +K+L + L +M + H ++ + G C + ++ EY Sbjct 509 RPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 568 Query 690 VEHGPLDVWLRRER----------GHVPMAW-----KMVVAQQLASALSYLENKNLVHGN 734 G L +LR R VP + QLA + YL ++ +H + Sbjct 569 ASKGNLREYLRARRPPGMEYSFDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD 628 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788 + RN+L+ + +K++D G+ ++ R+P W+APE L Sbjct 629 LAARNVLVTENNV-------MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRV 681 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846 + D W FG + EI G +P E + HR+ P +L + Sbjct 682 --YTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMR 739 Query 847 QCLTYEPTQRPSFRTILRDLTRL 869 C P+QRP+F+ ++ DL R+ Sbjct 740 DCWQAVPSQRPTFKQLVEDLDRI 762 >sp|Q61772|EPHA7_MOUSE Ephrin type-A receptor 7 OS=Mus musculus OX=10090 GN=Epha7 PE=1 SV=2 Length=998 Score = 291 bits (746), Expect = 2e-81, Method: Composition-based stats. Identities = 83/313 (27%), Positives = 145/313 (46%), Gaps = 19/313 (6%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 + + + + +K R +G G FG+V Sbjct 598 FHFKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGK 657 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VA+K LK + R + E I+ H +++ +G K + +V+E++ Sbjct 658 RD-VAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRG--KPVMIVIEFM 714 Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 G+L +L +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ Sbjct 715 ENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKV 774 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGL++ + + E G PV W APE ++ KF ASDVWS+G+ ++E++++ + Sbjct 775 SDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGE 834 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 M+ + + +E G RLP P CP ++ LM +CW+ + + R Sbjct 835 R--------------PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKDRAER 880 Query 1160 PTFENLIPILKTV 1172 P FE ++ IL + Sbjct 881 PKFEQIVGILDKM 893 Score = 270 bits (689), Expect = 5e-74, Method: Composition-based stats. Identities = 72/302 (24%), Positives = 124/302 (41%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D I +G G V GRL++ G +++ V + Sbjct 626 KELDASCIKIERVIGAGEFGEVCSGRLKLPGK---------------------RDVAVAI 664 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV RG ++V E++E+G LD +LR Sbjct 665 KTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLR 724 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL + VH ++ RNIL+ ++ K+SD Sbjct 725 KHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVN-------SNLVCKVSDF 777 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E V + W APE + ++A D W +G + E+ GE Sbjct 778 GLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYGER 835 Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + + +RLP CP L L C + +RP F I+ L ++ Sbjct 836 PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKDRAERPKFEQIVGILDKMIR 895 Query 872 HN 873 + Sbjct 896 NP 897 >sp|O42422|EPHA7_CHICK Ephrin type-A receptor 7 OS=Gallus gallus OX=9031 GN=EPHA7 PE=2 SV=1 Length=993 Score = 291 bits (744), Expect = 3e-81, Method: Composition-based stats. Identities = 85/313 (27%), Positives = 144/313 (46%), Gaps = 19/313 (6%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 + + + + +K R +G G FG+V Sbjct 593 FHFKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGK 652 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VA+K LK + R + E I+ H +++ +G K + +V+EY+ Sbjct 653 RD-VAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRG--KPVMIVIEYM 709 Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 G+L +L +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ Sbjct 710 ENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKV 769 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGL++ + + E G PV W APE ++ KF ASDVWS+G+ ++E++++ + Sbjct 770 SDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGE 829 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 M+ + + +E G RLP P CP ++ LM +CW+ E R Sbjct 830 R--------------PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERGER 875 Query 1160 PTFENLIPILKTV 1172 P FE ++ IL + Sbjct 876 PKFEQIVGILDKM 888 Score = 270 bits (690), Expect = 4e-74, Method: Composition-based stats. Identities = 74/302 (25%), Positives = 124/302 (41%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D I +G G V GRL++ G +++ V + Sbjct 621 KELDASCIKIERVIGAGEFGEVCSGRLKLPGK---------------------RDVAVAI 659 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV RG ++V EY+E+G LD +LR Sbjct 660 KTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEYMENGALDAFLR 719 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL + VH ++ RNIL+ ++ K+SD Sbjct 720 KHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVN-------SNLVCKVSDF 772 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E V + W APE + ++A D W +G + E+ GE Sbjct 773 GLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYGER 830 Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + + +RLP CP L L C E +RP F I+ L ++ Sbjct 831 PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERGERPKFEQIVGILDKMIR 890 Query 872 HN 873 + Sbjct 891 NP 892 >sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens OX=9606 GN=EPHB2 PE=1 SV=5 Length=1055 Score = 291 bits (746), Expect = 3e-81, Method: Composition-based stats. Identities = 81/325 (25%), Positives = 147/325 (45%), Gaps = 21/325 (6%) Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911 E T + T ++ + ++ +K + +G G FG+V Sbjct 576 EYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEV 635 Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 VA+K LK+ + R + E I+ H ++I +G Sbjct 636 CSGHLKLPGKRE-IFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKST- 693 Query 972 KSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029 + ++ E++ GSL +L ++ + QL+ + I GM YL +Y+HRDLAARN+ Sbjct 694 -PVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNI 752 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 L++++ + K+ DFGL++ + + Y G P+ W APE ++ KF ASDVWS+ Sbjct 753 LVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSY 812 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 G+ ++E++++ + MT + +E+ RLP P CP ++ L Sbjct 813 GIVMWEVMSYGER--------------PYWDMTNQDVINAIEQDYRLPPPMDCPSALHQL 858 Query 1148 MKNCWETEASFRPTFENLIPILKTV 1172 M +CW+ + + RP F ++ L + Sbjct 859 MLDCWQKDRNHRPKFGQIVNTLDKM 883 Score = 268 bits (685), Expect = 3e-73, Method: Composition-based stats. Identities = 70/304 (23%), Positives = 125/304 (41%), Gaps = 42/304 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G V G L++ G +E+ V + Sbjct 614 KEIDISCVKIEQVIGAGEFGEVCSGHLKLPGK---------------------REIFVAI 652 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + +++TE++E+G LD +LR Sbjct 653 KTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLR 712 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL + N VH ++ RNIL+ ++ K+SD Sbjct 713 QNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVN-------SNLVCKVSDF 765 Query 761 GVGL---GALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ S I W APE + ++A D W +G + E+ G Sbjct 766 GLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYG 823 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P + + + ++ +RLP P CP L L C + RP F I+ L ++ Sbjct 824 ERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 883 Query 870 QPHN 873 + Sbjct 884 IRNP 887 >sp|P54759|EPHA7_RAT Ephrin type-A receptor 7 OS=Rattus norvegicus OX=10116 GN=Epha7 PE=1 SV=1 Length=998 Score = 290 bits (743), Expect = 4e-81, Method: Composition-based stats. Identities = 84/313 (27%), Positives = 145/313 (46%), Gaps = 19/313 (6%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 + + + + +K R +G G FG+V Sbjct 598 FHFKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGK 657 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VA+K LK + R + E I+ H +++ +G K + +V+E++ Sbjct 658 RD-VAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRG--KPVMIVIEFM 714 Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 G+L +L +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ Sbjct 715 ENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKV 774 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGL++ + + E G PV W APE ++ KF ASDVWS+G+ ++E++++ + Sbjct 775 SDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGE 834 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 M+ + + +E G RLP P CP ++ LM +CW+ E + R Sbjct 835 R--------------PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAER 880 Query 1160 PTFENLIPILKTV 1172 P FE ++ IL + Sbjct 881 PKFEQIVGILDKM 893 Score = 269 bits (688), Expect = 7e-74, Method: Composition-based stats. Identities = 73/302 (24%), Positives = 124/302 (41%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D I +G G V GRL++ G +++ V + Sbjct 626 KELDASCIKIERVIGAGEFGEVCSGRLKLPGK---------------------RDVAVAI 664 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV RG ++V E++E+G LD +LR Sbjct 665 KTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLR 724 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL + VH ++ RNIL+ ++ K+SD Sbjct 725 KHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVN-------SNLVCKVSDF 777 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E V + W APE + ++A D W +G + E+ GE Sbjct 778 GLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYGER 835 Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + + +RLP CP L L C E +RP F I+ L ++ Sbjct 836 PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIR 895 Query 872 HN 873 + Sbjct 896 NP 897 >sp|Q15375|EPHA7_HUMAN Ephrin type-A receptor 7 OS=Homo sapiens OX=9606 GN=EPHA7 PE=1 SV=3 Length=998 Score = 290 bits (743), Expect = 4e-81, Method: Composition-based stats. Identities = 84/313 (27%), Positives = 145/313 (46%), Gaps = 19/313 (6%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 + + + + +K R +G G FG+V Sbjct 598 FHFKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGK 657 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VA+K LK + R + E I+ H +++ +G K + +V+E++ Sbjct 658 RD-VAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRG--KPVMIVIEFM 714 Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 G+L +L +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ Sbjct 715 ENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKV 774 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGL++ + + E G PV W APE ++ KF ASDVWS+G+ ++E++++ + Sbjct 775 SDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGE 834 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 M+ + + +E G RLP P CP ++ LM +CW+ E + R Sbjct 835 R--------------PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAER 880 Query 1160 PTFENLIPILKTV 1172 P FE ++ IL + Sbjct 881 PKFEQIVGILDKM 893 Score = 269 bits (688), Expect = 7e-74, Method: Composition-based stats. Identities = 73/302 (24%), Positives = 124/302 (41%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D I +G G V GRL++ G +++ V + Sbjct 626 KELDASCIKIERVIGAGEFGEVCSGRLKLPGK---------------------RDVAVAI 664 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV RG ++V E++E+G LD +LR Sbjct 665 KTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLR 724 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL + VH ++ RNIL+ ++ K+SD Sbjct 725 KHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVN-------SNLVCKVSDF 777 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E V + W APE + ++A D W +G + E+ GE Sbjct 778 GLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYGER 835 Query 814 PLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + + +RLP CP L L C E +RP F I+ L ++ Sbjct 836 PYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIR 895 Query 872 HN 873 + Sbjct 896 NP 897 >sp|P28693|EPHB2_CHICK Ephrin type-B receptor 2 OS=Gallus gallus OX=9031 GN=EPHB2 PE=1 SV=3 Length=1004 Score = 290 bits (743), Expect = 4e-81, Method: Composition-based stats. Identities = 78/315 (25%), Positives = 144/315 (46%), Gaps = 21/315 (7%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 + ++ + ++ +K + +G G FG+V Sbjct 604 LFVMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGK 663 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 VA+K LK+ + R + E I+ H ++I +G + ++ E++ Sbjct 664 RE-IFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSS--PVMIITEFM 720 Query 982 PLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 GSL +L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ Sbjct 721 ENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKV 780 Query 1040 GDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 DFGL++ + + Y G P+ W APE ++ KF ASDVWS+G+ ++E++++ Sbjct 781 SDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSY 840 Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157 + MT + +E+ RLP P CP ++ LM +CW+ + + Sbjct 841 GER--------------PYWDMTNQDVINAIEQDYRLPPPMDCPNALHQLMLDCWQKDRN 886 Query 1158 FRPTFENLIPILKTV 1172 RP F ++ L + Sbjct 887 HRPKFGQIVNTLDKM 901 Score = 269 bits (687), Expect = 9e-74, Method: Composition-based stats. Identities = 70/304 (23%), Positives = 125/304 (41%), Gaps = 42/304 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G V G L++ G +E+ V + Sbjct 632 KEIDISCVKIEQVIGAGEFGEVCSGHLKLPGK---------------------REIFVAI 670 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + +++TE++E+G LD +LR Sbjct 671 KTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMIITEFMENGSLDSFLR 730 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL + N VH ++ RNIL+ ++ K+SD Sbjct 731 QNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVN-------SNLVCKVSDF 783 Query 761 GVGL---GALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ S I W APE + ++A D W +G + E+ G Sbjct 784 GLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYG 841 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P + + + ++ +RLP P CP L L C + RP F I+ L ++ Sbjct 842 ERPYWDMTNQDVINAIEQDYRLPPPMDCPNALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 901 Query 870 QPHN 873 + Sbjct 902 IRNP 905 >sp|P16092|FGFR1_MOUSE Fibroblast growth factor receptor 1 OS=Mus musculus OX=10090 GN=Fgfr1 PE=1 SV=2 Length=822 Score = 287 bits (734), Expect = 4e-81, Method: Composition-based stats. Identities = 113/398 (28%), Positives = 179/398 (45%), Gaps = 41/398 (10%) Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 + GA L+ + +S ++K F+ + L + ++ + + Sbjct 379 IYCTGAFLISCMLGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVT--VSADSSAS 436 Query 857 PSFRTILRDLTRLQPHNLAD-VLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915 + +L +RL + P + L + LGEG FG+V L Sbjct 437 MNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAE 496 Query 916 YDPTNDGTG---EMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGE 971 + VAVK LK+D + S E+++++ + H++II G C G Sbjct 497 AIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG- 555 Query 972 KSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQLLLFAQQICEGMAYL 1014 L +++EY G+LR+YL P + L+ A Q+ GM YL Sbjct 556 -PLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYL 614 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 ++ IHRDLAARNVL+ D ++KI DFGLA+ + +YY+ +G PV W APE L Sbjct 615 ASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALF 673 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + + + SDVWSFGV L+E+ T L G + V L +LL+ G R+ Sbjct 674 DRIYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGVPVEELFKLLKEGHRM 719 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +P C E+Y +M++CW S RPTF+ L+ L + Sbjct 720 DKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 757 Score = 235 bits (600), Expect = 2e-63, Method: Composition-based stats. Identities = 66/348 (19%), Positives = 123/348 (35%), Gaps = 60/348 (17%) Query 556 GETSNLIIMRGARASPR---------TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606 S ++++R +R S L + + + + LG+G V Sbjct 436 SMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQV--- 492 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV 665 + E + + +V +K+L + L +M + Sbjct 493 --------------VLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMI 538 Query 666 -SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---------------RRERGHVPMA 709 H ++ + G C + ++ EY G L +L + Sbjct 539 GKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSK 598 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA--- 766 + A Q+A + YL +K +H ++ RN+L+ + +K++D G+ Sbjct 599 DLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNV-------MKIADFGLARDIHHI 651 Query 767 -LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 ++ R+P W+APE L + D W FG L EI G +P E Sbjct 652 DYYKKTTNGRLPVKWMAPEALFDRI--YTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEEL 709 Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + HR+ P +L + C P+QRP+F+ ++ DL R+ Sbjct 710 FKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 757 >sp|Q03137|EPHA4_MOUSE Ephrin type-A receptor 4 OS=Mus musculus OX=10090 GN=Epha4 PE=1 SV=2 Length=986 Score = 290 bits (743), Expect = 4e-81, Method: Composition-based stats. Identities = 86/332 (26%), Positives = 151/332 (45%), Gaps = 21/332 (6%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 + S+ + + ++ + + +K + + Sbjct 568 VISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVI 627 Query 904 GEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 G G FG+V G E+ VA+K LKA + R + E I+ H +II Sbjct 628 GVGEFGEVCSGRLKV--PGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHL 685 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYI 1020 +G K + ++ EY+ GSL +L ++ + QL+ + I GM YL Y+ Sbjct 686 EGVVTKC--KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYV 743 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARN+L++++ + K+ DFG+++ + + E G P+ W APE + KF Sbjct 744 HRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTS 803 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ASDVWS+G+ ++E++++ + M+ + + +E G RLP P C Sbjct 804 ASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVIKAIEEGYRLPPPMDC 849 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P ++ LM +CW+ E S RP F ++ +L + Sbjct 850 PIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881 Score = 269 bits (687), Expect = 9e-74, Method: Composition-based stats. Identities = 77/302 (25%), Positives = 124/302 (41%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D I +G G V GRL+V G +E+ V + Sbjct 614 KEIDASCIKIEKVIGVGEFGEVCSGRLKVPGK---------------------REICVAI 652 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + D F AS+M Q H ++ + GV + +++TEY+E+G LD +LR Sbjct 653 KTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLR 712 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + + S + YL + + VH ++ RNIL+ ++ K+SD Sbjct 713 KNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVN-------SNLVCKVSDF 765 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E I W APE + ++A D W +G + E+ GE Sbjct 766 GMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER 823 Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + + +RLP P CP L L C E + RP F I+ L +L Sbjct 824 PYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIR 883 Query 872 HN 873 + Sbjct 884 NP 885 >sp|P54764|EPHA4_HUMAN Ephrin type-A receptor 4 OS=Homo sapiens OX=9606 GN=EPHA4 PE=1 SV=1 Length=986 Score = 290 bits (743), Expect = 4e-81, Method: Composition-based stats. Identities = 86/332 (26%), Positives = 151/332 (45%), Gaps = 21/332 (6%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 + S+ + + ++ + + +K + + Sbjct 568 VISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVI 627 Query 904 GEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 G G FG+V G E+ VA+K LKA + R + E I+ H +II Sbjct 628 GVGEFGEVCSGRLKV--PGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHL 685 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYI 1020 +G K + ++ EY+ GSL +L ++ + QL+ + I GM YL Y+ Sbjct 686 EGVVTKC--KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYV 743 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARN+L++++ + K+ DFG+++ + + E G P+ W APE + KF Sbjct 744 HRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTS 803 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ASDVWS+G+ ++E++++ + M+ + + +E G RLP P C Sbjct 804 ASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVIKAIEEGYRLPPPMDC 849 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P ++ LM +CW+ E S RP F ++ +L + Sbjct 850 PIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881 Score = 269 bits (687), Expect = 9e-74, Method: Composition-based stats. Identities = 77/302 (25%), Positives = 124/302 (41%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D I +G G V GRL+V G +E+ V + Sbjct 614 KEIDASCIKIEKVIGVGEFGEVCSGRLKVPGK---------------------REICVAI 652 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + D F AS+M Q H ++ + GV + +++TEY+E+G LD +LR Sbjct 653 KTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLR 712 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + + S + YL + + VH ++ RNIL+ ++ K+SD Sbjct 713 KNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVN-------SNLVCKVSDF 765 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E I W APE + ++A D W +G + E+ GE Sbjct 766 GMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER 823 Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + + +RLP P CP L L C E + RP F I+ L +L Sbjct 824 PYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIR 883 Query 872 HN 873 + Sbjct 884 NP 885 >sp|Q07496|EPHA4_CHICK Ephrin type-A receptor 4 OS=Gallus gallus OX=9031 GN=EPHA4 PE=1 SV=2 Length=986 Score = 290 bits (743), Expect = 4e-81, Method: Composition-based stats. Identities = 86/332 (26%), Positives = 151/332 (45%), Gaps = 21/332 (6%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 + S+ + + ++ + + +K + + Sbjct 568 VISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVI 627 Query 904 GEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 G G FG+V G E+ VA+K LKA + R + E I+ H +II Sbjct 628 GVGEFGEVCSGRLKV--PGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHL 685 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYI 1020 +G K + ++ EY+ GSL +L ++ + QL+ + I GM YL Y+ Sbjct 686 EGVVTKC--KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYV 743 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARN+L++++ + K+ DFG+++ + + E G P+ W APE + KF Sbjct 744 HRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTS 803 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ASDVWS+G+ ++E++++ + M+ + + +E G RLP P C Sbjct 804 ASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVIKAIEEGYRLPPPMDC 849 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P ++ LM +CW+ E S RP F ++ +L + Sbjct 850 PIALHQLMLDCWQKERSDRPKFGQIVNMLDKL 881 Score = 269 bits (687), Expect = 9e-74, Method: Composition-based stats. Identities = 77/302 (25%), Positives = 124/302 (41%), Gaps = 40/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D I +G G V GRL+V G +E+ V + Sbjct 614 KEIDASCIKIEKVIGVGEFGEVCSGRLKVPGK---------------------REICVAI 652 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + D F AS+M Q H ++ + GV + +++TEY+E+G LD +LR Sbjct 653 KTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLR 712 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + + S + YL + + VH ++ RNIL+ ++ K+SD Sbjct 713 KNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVN-------SNLVCKVSDF 765 Query 761 GVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ E I W APE + ++A D W +G + E+ GE Sbjct 766 GMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYGER 823 Query 814 PLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + + +RLP P CP L L C E + RP F I+ L +L Sbjct 824 PYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIR 883 Query 872 HN 873 + Sbjct 884 NP 885 >sp|P11362|FGFR1_HUMAN Fibroblast growth factor receptor 1 OS=Homo sapiens OX=9606 GN=FGFR1 PE=1 SV=3 Length=822 Score = 287 bits (734), Expect = 4e-81, Method: Composition-based stats. Identities = 103/313 (33%), Positives = 153/313 (49%), Gaps = 38/313 (12%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---EMVAVKALKADCG 937 + P + L + LGEG FG+V L + VAVK LK+D Sbjct 462 EYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDAT 521 Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990 + S E+++++ + H++II G C G L +++EY G+LR+YL Sbjct 522 EKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLQARRPP 579 Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI Sbjct 580 GLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKI 639 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T Sbjct 640 ADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--- 695 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L G + V L +LL+ G R+ +P C E+Y +M++CW S R Sbjct 696 -----------LGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQR 744 Query 1160 PTFENLIPILKTV 1172 PTF+ L+ L + Sbjct 745 PTFKQLVEDLDRI 757 Score = 236 bits (601), Expect = 2e-63, Method: Composition-based stats. Identities = 66/348 (19%), Positives = 123/348 (35%), Gaps = 60/348 (17%) Query 556 GETSNLIIMRGARASPR---------TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606 S ++++R +R S L + + + + LG+G V Sbjct 436 SMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQV--- 492 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV 665 + E + + +V +K+L + L +M + Sbjct 493 --------------VLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMI 538 Query 666 -SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---------------RRERGHVPMA 709 H ++ + G C + ++ EY G L +L + Sbjct 539 GKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSK 598 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA--- 766 + A Q+A + YL +K +H ++ RN+L+ + +K++D G+ Sbjct 599 DLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNV-------MKIADFGLARDIHHI 651 Query 767 -LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 ++ R+P W+APE L + D W FG L EI G +P E Sbjct 652 DYYKKTTNGRLPVKWMAPEALFDRI--YTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEEL 709 Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + HR+ P +L + C P+QRP+F+ ++ DL R+ Sbjct 710 FKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 757 >sp|Q04589|FGFR1_RAT Fibroblast growth factor receptor 1 OS=Rattus norvegicus OX=10116 GN=Fgfr1 PE=1 SV=1 Length=822 Score = 286 bits (733), Expect = 5e-81, Method: Composition-based stats. Identities = 103/313 (33%), Positives = 153/313 (49%), Gaps = 38/313 (12%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---EMVAVKALKADCG 937 + P + L + LGEG FG+V L + VAVK LK+D Sbjct 462 EYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDAT 521 Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990 + S E+++++ + H++II G C G L +++EY G+LR+YL Sbjct 522 EKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLQARRPP 579 Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI Sbjct 580 GLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKI 639 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T Sbjct 640 ADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--- 695 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L G + V L +LL+ G R+ +P C E+Y +M++CW S R Sbjct 696 -----------LGGSPNPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWNAVPSQR 744 Query 1160 PTFENLIPILKTV 1172 PTF+ L+ L + Sbjct 745 PTFKQLVEDLDRI 757 Score = 235 bits (600), Expect = 2e-63, Method: Composition-based stats. Identities = 66/348 (19%), Positives = 123/348 (35%), Gaps = 60/348 (17%) Query 556 GETSNLIIMRGARASPR---------TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606 S ++++R +R S L + + + + LG+G V Sbjct 436 SMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQV--- 492 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV 665 + E + + +V +K+L + L +M + Sbjct 493 --------------VLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMI 538 Query 666 -SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---------------RRERGHVPMA 709 H ++ + G C + ++ EY G L +L + Sbjct 539 GKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSK 598 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA--- 766 + A Q+A + YL +K +H ++ RN+L+ + +K++D G+ Sbjct 599 DLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNV-------MKIADFGLARDIHHI 651 Query 767 -LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 ++ R+P W+APE L + D W FG L EI G +P E Sbjct 652 DYYKKTTNGRLPVKWMAPEALFDRI--YTHQSDVWSFGVLLWEIFTLGGSPNPGVPVEEL 709 Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + HR+ P +L + C P+QRP+F+ ++ DL R+ Sbjct 710 FKLLKEGHRMDKPSNCTNELYMMMRDCWNAVPSQRPTFKQLVEDLDRI 757 >sp|P21803|FGFR2_MOUSE Fibroblast growth factor receptor 2 OS=Mus musculus OX=10090 GN=Fgfr2 PE=1 SV=4 Length=821 Score = 286 bits (732), Expect = 6e-81, Method: Composition-based stats. Identities = 101/313 (32%), Positives = 153/313 (49%), Gaps = 38/313 (12%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCG 937 + P F + L + LGEG FG+V + + + VAVK LK D Sbjct 465 EYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDAT 524 Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990 + S E+++++ + H++II G C G L +++EY G+LR+YL Sbjct 525 EKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPP 582 Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P + L+ Q+ GM YL +Q IHRDLAARNVL+ + ++KI Sbjct 583 GMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKI 642 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV ++E+ T Sbjct 643 ADFGLARDI-NNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT--- 698 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L G + V L +LL+ G R+ +P C E+Y +M++CW S R Sbjct 699 -----------LGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMRDCWHAVPSQR 747 Query 1160 PTFENLIPILKTV 1172 PTF+ L+ L + Sbjct 748 PTFKQLVEDLDRI 760 Score = 234 bits (597), Expect = 6e-63, Method: Composition-based stats. Identities = 65/323 (20%), Positives = 117/323 (36%), Gaps = 51/323 (16%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 L + + ++T LG+G V + E + Sbjct 464 SEYELPEDPKWEFPRDKLTLGKPLGEGCFGQV-----------------VMAEAVGIDKD 506 Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689 + + V +K+L + L +M + H ++ + G C + ++ EY Sbjct 507 KPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 566 Query 690 VEHGPLDVWLRRER----------GHVPMAW-----KMVVAQQLASALSYLENKNLVHGN 734 G L +LR R VP + QLA + YL ++ +H + Sbjct 567 ASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD 626 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788 + RN+L+ + +K++D G+ ++ R+P W+APE L Sbjct 627 LAARNVLVTENNV-------MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRV 679 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846 + D W FG + EI G +P E + HR+ P +L + Sbjct 680 --YTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPTNCTNELYMMMR 737 Query 847 QCLTYEPTQRPSFRTILRDLTRL 869 C P+QRP+F+ ++ DL R+ Sbjct 738 DCWHAVPSQRPTFKQLVEDLDRI 760 >sp|P09759|EPHB1_RAT Ephrin type-B receptor 1 OS=Rattus norvegicus OX=10116 GN=Ephb1 PE=1 SV=2 Length=984 Score = 290 bits (741), Expect = 7e-81, Method: Composition-based stats. Identities = 79/308 (26%), Positives = 143/308 (46%), Gaps = 21/308 (7%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 ++ + ++ ++K +G G FG+V VA Sbjct 591 MKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKRE-IYVA 649 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LKA + R + E I+ H +II+ +G + + ++ E++ G+L Sbjct 650 IKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGALDS 707 Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 +L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++ Sbjct 708 FLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 767 Query 1047 AVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 + + Y G PV W APE + KF ASDVWS+G+ ++E+++ + Sbjct 768 YLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGER---- 823 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 M+ + +E+ RLP P CP ++ LM +CW+ + + RP F Sbjct 824 ----------PYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAE 873 Query 1165 LIPILKTV 1172 ++ L + Sbjct 874 IVNTLDKM 881 Score = 278 bits (710), Expect = 7e-77, Method: Composition-based stats. Identities = 73/304 (24%), Positives = 126/304 (41%), Gaps = 42/304 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G VY+GRL++ G +E+ V + Sbjct 612 KEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGK---------------------REIYVAI 650 Query 642 KVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L F AS+M Q H ++ + GV + +++TE++E+G LD +LR Sbjct 651 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 710 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD Sbjct 711 QNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 763 Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ +IP W APE + ++A D W +G + E+ G Sbjct 764 GLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSFG 821 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P S + + ++ +RLP P CP L L C + RP F I+ L ++ Sbjct 822 ERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKM 881 Query 870 QPHN 873 + Sbjct 882 IRNP 885 >sp|Q8CBF3|EPHB1_MOUSE Ephrin type-B receptor 1 OS=Mus musculus OX=10090 GN=Ephb1 PE=1 SV=1 Length=984 Score = 290 bits (741), Expect = 7e-81, Method: Composition-based stats. Identities = 79/308 (26%), Positives = 143/308 (46%), Gaps = 21/308 (7%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 ++ + ++ ++K +G G FG+V VA Sbjct 591 MKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKRE-IYVA 649 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LKA + R + E I+ H +II+ +G + + ++ E++ G+L Sbjct 650 IKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGALDS 707 Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 +L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++ Sbjct 708 FLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 767 Query 1047 AVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 + + Y G PV W APE + KF ASDVWS+G+ ++E+++ + Sbjct 768 YLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGER---- 823 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 M+ + +E+ RLP P CP ++ LM +CW+ + + RP F Sbjct 824 ----------PYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAE 873 Query 1165 LIPILKTV 1172 ++ L + Sbjct 874 IVNTLDKM 881 Score = 278 bits (710), Expect = 7e-77, Method: Composition-based stats. Identities = 73/304 (24%), Positives = 126/304 (41%), Gaps = 42/304 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G VY+GRL++ G +E+ V + Sbjct 612 KEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGK---------------------REIYVAI 650 Query 642 KVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L F AS+M Q H ++ + GV + +++TE++E+G LD +LR Sbjct 651 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 710 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD Sbjct 711 QNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 763 Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ +IP W APE + ++A D W +G + E+ G Sbjct 764 GLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSFG 821 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P S + + ++ +RLP P CP L L C + RP F I+ L ++ Sbjct 822 ERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKM 881 Query 870 QPHN 873 + Sbjct 882 IRNP 885 >sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo sapiens OX=9606 GN=EPHB1 PE=1 SV=1 Length=984 Score = 289 bits (740), Expect = 9e-81, Method: Composition-based stats. Identities = 79/308 (26%), Positives = 143/308 (46%), Gaps = 21/308 (7%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 ++ + ++ ++K +G G FG+V VA Sbjct 591 MKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKRE-IYVA 649 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LKA + R + E I+ H +II+ +G + + ++ E++ G+L Sbjct 650 IKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGALDS 707 Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 +L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++ Sbjct 708 FLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 767 Query 1047 AVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 + + Y G PV W APE + KF ASDVWS+G+ ++E+++ + Sbjct 768 YLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGER---- 823 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 M+ + +E+ RLP P CP ++ LM +CW+ + + RP F Sbjct 824 ----------PYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAE 873 Query 1165 LIPILKTV 1172 ++ L + Sbjct 874 IVNTLDKM 881 Score = 277 bits (709), Expect = 1e-76, Method: Composition-based stats. Identities = 73/304 (24%), Positives = 126/304 (41%), Gaps = 42/304 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G VY+GRL++ G +E+ V + Sbjct 612 KEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGK---------------------REIYVAI 650 Query 642 KVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L F AS+M Q H ++ + GV + +++TE++E+G LD +LR Sbjct 651 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 710 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD Sbjct 711 QNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVN-------SNLVCKVSDF 763 Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ +IP W APE + ++A D W +G + E+ G Sbjct 764 GLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSFG 821 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P S + + ++ +RLP P CP L L C + RP F I+ L ++ Sbjct 822 ERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKM 881 Query 870 QPHN 873 + Sbjct 882 IRNP 885 >sp|Q91287|FGFR3_PLEWA Fibroblast growth factor receptor 3 OS=Pleurodeles waltl OX=8319 GN=FGFR3 PE=2 SV=1 Length=796 Score = 285 bits (729), Expect = 1e-80, Method: Composition-based stats. Identities = 104/306 (34%), Positives = 149/306 (49%), Gaps = 38/306 (12%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGW 944 + L + LGEG FG+V + VAVK LK D + S Sbjct 448 PKWELSRSRLTLGKPLGEGCFGQVVMADAVGIEKDKPNKATSVAVKMLKDDATDKDLSDL 507 Query 945 KQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------------- 990 E+++++ + H++II G C G L +++EY G+LR+YL Sbjct 508 VSEMEMMKMIGKHKNIINLLGACTQDG--PLYVLVEYASKGNLREYLRARRPPGMDYSFD 565 Query 991 ----PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 P + L+ A Q+ GM YL +Q IHRDLAARNVL+ +D ++KI DFGLA+ Sbjct 566 TCKLPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLAR 625 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 V +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T Sbjct 626 DV-HNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFT---------- 674 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L G + V L +LL+ G R+ +P C E+Y +M+ CW S RPTF+ L+ Sbjct 675 ----LGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFKQLV 730 Query 1167 PILKTV 1172 L V Sbjct 731 EDLDRV 736 Score = 238 bits (607), Expect = 2e-64, Method: Composition-based stats. Identities = 73/354 (21%), Positives = 128/354 (36%), Gaps = 62/354 (18%) Query 545 FSLRRC--CLPQPGETSNLIIMRGARAS----PRTLNLSQLSF-----HRVDQKEITQLS 593 F L+R SN ++R R S P N+S+L + + +T Sbjct 402 FPLKRQVSLESNSSMNSNTPLVRITRLSSSDGPMLANVSELELPADPKWELSRSRLTLGK 461 Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LG+G V + + + + V +K+L D L Sbjct 462 PLGEGCFGQV-----------------VMADAVGIEKDKPNKATSVAVKMLKDDATDKDL 504 Query 654 -AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG------- 704 +M + H ++ + G C + ++ EY G L +LR R Sbjct 505 SDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSF 564 Query 705 ---HVPMAWK-----MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +P + A Q+A + YL ++ +H ++ RN+L+ + +K Sbjct 565 DTCKLPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNV-------MK 617 Query 757 LSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 ++D G+ ++ R+P W+APE L + D W FG L EI Sbjct 618 IADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRV--YTHQSDVWSFGVLLWEIFTL 675 Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 G +P E + HR+ P +L + +C P+QRP+F+ + Sbjct 676 GGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFKQL 729 >sp|P03949|ABL1_CAEEL Tyrosine-protein kinase abl-1 OS=Caenorhabditis elegans OX=6239 GN=abl-1 PE=1 SV=4 Length=1224 Score = 292 bits (747), Expect = 1e-80, Method: Composition-based stats. Identities = 95/429 (22%), Positives = 160/429 (37%), Gaps = 66/429 (15%) Query 450 GIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIE 508 HG + +A L G +L+ S + + ++V R+ + I Sbjct 194 WYHGKISRSDSEAILGSGITGSFLVRESETSIGQYTISVRHDG---------RVFHYRIN 244 Query 509 QQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGAR 568 + + F ++ EL + A C L P + +G Sbjct 245 VDNTEKMFITQEVKFRTLGELVHH---HSVHADGLI-----CLLMYPASKKD----KGRG 292 Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 + N +D+ EI + LG G +VYEG + Sbjct 293 LFSLSPNAP--DEWELDRSEIIMHNKLGGGQYGDVYEGYWKRHDC--------------- 335 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 + +K L + F A++M + H +L + GVC ++TE Sbjct 336 ---------TIAVKALKEDAMPLH-EFLAEAAIMKDLHHKNLVRLLGVCTHEAPFYIITE 385 Query 689 YVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 ++ +G L +LRR ++ +P + +A Q+AS +SYLE ++ +H ++ RN L++ + Sbjct 386 FMCNGNLLEYLRRTDKSLLPPIILVQMASQIASGMSYLEARHFIHRDLAARNCLVSEHNI 445 Query 748 AEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKWGFGA 802 +K++D G+ I W APE L N+ S+ D W FG Sbjct 446 -------VKIADFGLARFMKEDTYTAHAGAKFPIKWTAPEGLA--FNTFSSKSDVWAFGV 496 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860 L EI G AP S + R+ P+ P + L QC + P+ RP FR Sbjct 497 LLWEIATYGMAPYPGVELSNVYGLLENGFRMDGPQGCPPSVYRLMLQCWNWSPSDRPRFR 556 Query 861 TILRDLTRL 869 I +L L Sbjct 557 DIHFNLENL 565 Score = 271 bits (694), Expect = 9e-74, Method: Composition-based stats. Identities = 98/292 (34%), Positives = 142/292 (49%), Gaps = 27/292 (9%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 A D + + LG G +G V + +D T +AVKALK D P H Sbjct 298 PNAPDEWELDRSEIIMHNKLGGGQYGDVYEGYWK-RHDCT---IAVKALKEDAMPLH--E 351 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ---L 1000 + E I++ L+H+++++ G C E ++ E++ G+L +YL R L L Sbjct 352 FLAEAAIMKDLHHKNLVRLLGVCTH--EAPFYIITEFMCNGNLLEYLRRTDKSLLPPIIL 409 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 + A QI GM+YL A+H+IHRDLAARN L+ +VKI DFGLA+ + E + Y Sbjct 410 VQMASQIASGMSYLEARHFIHRDLAARNCLVSEHNIVKIADFGLARFMKE--DTYTAHAG 467 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 P+ W APE L F SDVW+FGV L+E+ T+ + + Sbjct 468 AKFPIKWTAPEGLAFNTFSSKSDVWAFGVLLWEIATYGMA--------------PYPGVE 513 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + + LLE G R+ P CP VY LM CW S RP F ++ L+ + Sbjct 514 LSNVYGLLENGFRMDGPQGCPPSVYRLMLQCWNWSPSDRPRFRDIHFNLENL 565 >sp|Q91147|FGFR2_NOTVI Fibroblast growth factor receptor 2 OS=Notophthalmus viridescens OX=8316 GN=FGFR2 PE=2 SV=1 Length=729 Score = 283 bits (724), Expect = 1e-80, Method: Composition-based stats. Identities = 105/343 (31%), Positives = 157/343 (46%), Gaps = 53/343 (15%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE---MVAVKALKADCG 937 + P + + L + LGEG FG+V + + + VAVK LK D Sbjct 373 EYELPEDPKWEYPREKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKDAATVAVKMLKDDAT 432 Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990 + S E+++++ + H++II G C G L +++EY G+LR+YL Sbjct 433 EKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRTRRPP 490 Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P + L+ Q+ GM YL +Q IHRDLAARNVL+ ++KI Sbjct 491 GMEYSFDINRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTETNVMKI 550 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV ++E+ T Sbjct 551 ADFGLARDI-NNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT--- 606 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L G + V L +LL+ G R+ +P C E+Y +M +CW S R Sbjct 607 -----------LGGSPYPGIPVEELFKLLKEGHRMDKPGNCTNELYTMMTDCWRAVPSQR 655 Query 1160 PTFENLIPILKTV---------------HEKYQGQAPSVFSVC 1187 PTF+ L+ L + E+Y P S C Sbjct 656 PTFKQLVEDLDRILTQTTNEEYLDLNNPLEQYSPSYPDTRSSC 698 Score = 231 bits (588), Expect = 2e-62, Method: Composition-based stats. Identities = 65/332 (20%), Positives = 119/332 (36%), Gaps = 51/332 (15%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 L + ++++T LG+G V + E + Sbjct 372 SEYELPEDPKWEYPREKLTLGKPLGEGCFGQV-----------------VMAEAVGIDKD 414 Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689 V +K+L + L +M + H ++ + G C + ++ EY Sbjct 415 RPKDAATVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 474 Query 690 VEHGPLDVWLRRER----------GHVPMAW-----KMVVAQQLASALSYLENKNLVHGN 734 G L +LR R +P + QLA + YL ++ +H + Sbjct 475 ASKGNLREYLRTRRPPGMEYSFDINRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD 534 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788 + RN+L+ + +K++D G+ ++ R+P W+APE L Sbjct 535 LAARNVLVTETNV-------MKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRV 587 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846 + D W FG + EI G +P E + HR+ P +L T+ + Sbjct 588 --YTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPGNCTNELYTMMT 645 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 C P+QRP+F+ ++ DL R+ + Sbjct 646 DCWRAVPSQRPTFKQLVEDLDRILTQTTNEEY 677 >sp|Q91285|FGFR1_PLEWA Fibroblast growth factor receptor 1 OS=Pleurodeles waltl OX=8319 GN=FGFR1 PE=2 SV=1 Length=816 Score = 285 bits (728), Expect = 2e-80, Method: Composition-based stats. Identities = 102/313 (33%), Positives = 154/313 (49%), Gaps = 38/313 (12%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---EMVAVKALKADCG 937 + P F + L + LGEG FG+V + + VAVK LK+D Sbjct 458 EYELPEDPRWEFSRDRLILGKPLGEGCFGQVVMGEAIGLDKEKPNRVTKVAVKMLKSDAT 517 Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----- 991 + S E+++++ + H++II G C G L +++EY G+LR+YL Sbjct 518 EKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRARRPP 575 Query 992 ------------RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 + + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI Sbjct 576 GMEYCYNPIHVSKDMLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDSVMKI 635 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T Sbjct 636 ADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--- 691 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L G + V L +LL+ G R+ +P C E+Y +M++CW S R Sbjct 692 -----------LGGSPYPGVPVEELFKLLKEGHRMDKPGNCTNELYMMMRDCWHAVPSQR 740 Query 1160 PTFENLIPILKTV 1172 PTF+ L+ L + Sbjct 741 PTFKQLVEDLDRI 753 Score = 235 bits (599), Expect = 3e-63, Method: Composition-based stats. Identities = 67/343 (20%), Positives = 119/343 (35%), Gaps = 56/343 (16%) Query 566 GARASPRTLNLSQLSFHRVDQKEIT-----QLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620 + SP +S+ + E + LG+G V Sbjct 446 SSSGSPMLTGVSEYELPEDPRWEFSRDRLILGKPLGEGCFGQV----------------- 488 Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCV 678 + E + + +V +K+L + L +M + H ++ + G C Sbjct 489 VMGEAIGLDKEKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACT 548 Query 679 RGPENIMVTEYVEHGPLDVWLRRERGH---------------VPMAWKMVVAQQLASALS 723 + ++ EY G L +LR R + + A Q+A + Sbjct 549 QDGPLYVIVEYASKGNLREYLRARRPPGMEYCYNPIHVSKDMLSFKDLVSCAYQVARGME 608 Query 724 YLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP-- 777 YL +K +H ++ RN+L+ +K++D G+ ++ R+P Sbjct 609 YLASKKCIHRDLAARNVLVTE-------DSVMKIADFGLARDIHHIDYYKKTTNGRLPVK 661 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PE 835 W+APE L + D W FG L EI G +P E + HR+ P Sbjct 662 WMAPEALFDRI--YTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPG 719 Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 +L + C P+QRP+F+ ++ DL R+ Sbjct 720 NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVAMTSNQEY 762 >sp|P18460|FGFR3_CHICK Fibroblast growth factor receptor 3 OS=Gallus gallus OX=9031 GN=FGFR3 PE=2 SV=1 Length=806 Score = 285 bits (728), Expect = 2e-80, Method: Composition-based stats. Identities = 120/415 (29%), Positives = 182/415 (44%), Gaps = 47/415 (11%) Query 782 ECLPGGANSLSTAMDKWGFG--ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP 839 E L +S S +G L + + + P++K ++ + Sbjct 354 EELMEMDDSGSVYAGILSYGTGLVLFILVLVIVIICRMKMPNKKAMNTTTVQKVSKFP-- 411 Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD-VLTVNPDSPASDPTVFHKRYLK 898 L Q ++ E + T L +TRL + + P + L Sbjct 412 ----LKRQQVSLESNSSMNSNTPLVRITRLSSSDGPMLANVSELELPPDPKWELARSRLT 467 Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGWKQEIDILRTL- 954 + LGEG FG+V + + VAVK LK D + S E+++++ + Sbjct 468 LGKPLGEGCFGQVVMAEAIGIDKDKPNKAITVAVKMLKDDATDKDLSDLVSEMEMMKMIG 527 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGL 997 H++II G C G L +++EY G+LR+YL P + Sbjct 528 KHKNIINLLGACTQDG--PLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKLPEEQLTF 585 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 L+ A Q+ GM YL +Q IHRDLAARNVL+ D ++KI DFGLA+ V +YY+ Sbjct 586 KDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDV-HNIDYYKK 644 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 +G PV W APE L + + + SDVWSFGV L+E+ T L G Sbjct 645 TTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFT--------------LGGSPYP 690 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + V L +LL+ G R+ +P C ++Y +M+ CW S RPTF+ L+ L V Sbjct 691 GIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRV 745 Score = 240 bits (612), Expect = 5e-65, Method: Composition-based stats. Identities = 78/371 (21%), Positives = 136/371 (37%), Gaps = 63/371 (17%) Query 545 FSLRRCCLPQPGETS---NLIIMRGARAS----PRTLNLSQLSF-----HRVDQKEITQL 592 F L+R + +S N ++R R S P N+S+L + + +T Sbjct 410 FPLKRQQVSLESNSSMNSNTPLVRITRLSSSDGPMLANVSELELPPDPKWELARSRLTLG 469 Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 LG+G V + E + + + V +K+L D Sbjct 470 KPLGEGCFGQV-----------------VMAEAIGIDKDKPNKAITVAVKMLKDDATDKD 512 Query 653 L-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG------ 704 L +M + H ++ + G C + ++ EY G L +LR R Sbjct 513 LSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYS 572 Query 705 ----HVPMAWK-----MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +P + A Q+A + YL ++ +H ++ RN+L+ + + Sbjct 573 FDTCKLPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNV-------M 625 Query 756 KLSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 K++D G+ ++ R+P W+APE L + D W FG L EI Sbjct 626 KIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRV--YTHQSDVWSFGVLLWEIFT 683 Query 810 DGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 G +P E + HR+ P L + +C P+QRP+F+ ++ DL Sbjct 684 LGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAVPSQRPTFKQLVEDLD 743 Query 868 RLQPHNLADVL 878 R+ D Sbjct 744 RVLTMTSTDEY 754 >sp|Q64434|PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus musculus OX=10090 GN=Ptk6 PE=1 SV=1 Length=451 Score = 274 bits (700), Expect = 2e-80, Method: Composition-based stats. Identities = 99/465 (21%), Positives = 158/465 (34%), Gaps = 83/465 (18%) Query 418 SLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED---GLYLIH 474 +L +GY +YL A V S G + +L+ ED G +LI Sbjct 56 ALAEGYV-----PHNYL----AEKETVES-EPWFFGCISRSEAMHRLQAEDNSKGAFLIR 105 Query 475 WSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQ 534 S +L+V +R + I + + + SF ++ EL + Sbjct 106 VSQKPGADYVLSVRDAQA---------VRHYRIWKNNEGRLHLNEAVSFSNLSELVDYHK 156 Query 535 GCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSH 594 L L C +T L ++E T Sbjct 157 TQSL---SHGLQLSMPCWKH-----------------KTEPLPHWDDWERPREEFTLCKK 196 Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LG G V+E + ++ V +KV+ + Sbjct 197 LGAGYFGEVFEALWKG-------------------------QVHVAVKVISRDNLLHQHT 231 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMV 713 F M ++ H H+ ++ V G ++TE + G L LR +P+ + Sbjct 232 FQAEIQAMKKLRHKHILSLYAVATAGDPVYIITELMPKGNLLQLLRDSDEKALPILELVD 291 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSR 769 A Q+A + YLE++N +H ++ RN+L+ L K+ D G+ Sbjct 292 FASQVAEGMCYLESQNYIHRDLAARNVLVTENNL-------CKVGDFGLARLVKEDIYLS 344 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 E W APE L G S D W FG L EI G+ P S E Sbjct 345 HEHNVPYKWTAPEALSRG--HYSIKSDVWSFGVLLHEIFSRGQMPYPGMSNHETFLRVDA 402 Query 830 QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 +R+P P P + L C + +P QRP F+ + LT + + Sbjct 403 GYRMPCPLECPPNIHKLMLSCWSRDPKQRPCFKDLCEKLTGITRY 447 Score = 261 bits (667), Expect = 1e-75, Method: Composition-based stats. Identities = 89/302 (29%), Positives = 140/302 (46%), Gaps = 28/302 (9%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933 + P D + + LG G+FG+V + VAVK + Sbjct 168 MPCWKHKTEPLPHWDDWERPREEFTLCKKLGAGYFGEVFEALWKGQ-----VHVAVKVIS 222 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991 D H+ ++ EI ++ L H+HI+ + ++ E +P G+L L Sbjct 223 RDNLL-HQHTFQAEIQAMKKLRHKHILSLYAVATAGD--PVYIITELMPKGNLLQLLRDS 279 Query 992 -RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 ++ + +L+ FA Q+ EGM YL +Q+YIHRDLAARNVL+ + L K+GDFGLA+ V E Sbjct 280 DEKALPILELVDFASQVAEGMCYLESQNYIHRDLAARNVLVTENNLCKVGDFGLARLVKE 339 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 + + + P W APE L + SDVWSFGV L+E+ + Sbjct 340 D---IYLSHEHNVPYKWTAPEALSRGHYSIKSDVWSFGVLLHEIFSRGQ----------- 385 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + M+ ++ G R+P P +CP ++ LM +CW + RP F++L L Sbjct 386 ---MPYPGMSNHETFLRVDAGYRMPCPLECPPNIHKLMLSCWSRDPKQRPCFKDLCEKLT 442 Query 1171 TV 1172 + Sbjct 443 GI 444 >sp|Q13882|PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo sapiens OX=9606 GN=PTK6 PE=1 SV=1 Length=451 Score = 274 bits (700), Expect = 3e-80, Method: Composition-based stats. Identities = 93/444 (21%), Positives = 151/444 (34%), Gaps = 73/444 (16%) Query 430 SSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPE---DGLYLIHWSTSHPYRLILT 486 + Y+ H R + G + +L+ E G +LI S +L+ Sbjct 58 AQGYVPHNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLS 117 Query 487 VAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFS 546 V +R + I ++ G + SF S+ EL + L Sbjct 118 VRDTQA---------VRHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRAQSL---SHGLR 165 Query 547 LRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606 L C E L ++E T LG G V+EG Sbjct 166 LAAPCRKHEPEP-----------------LPHWDDWERPREEFTLCRKLGSGYFGEVFEG 208 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS 666 + ++V +KV+ + M ++ Sbjct 209 LWKDR-------------------------VQVAIKVISRDNLLHQQMLQSEIQAMKKLR 243 Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYL 725 H H+ ++ V G ++TE + G L LR +P++ + +A Q+A + YL Sbjct 244 HKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYL 303 Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIPWLAP 781 E++N +H ++ RNIL+ G + K+ D G+ + W AP Sbjct 304 ESQNYIHRDLAARNILV-------GENTLCKVGDFGLARLIKEDVYLSHDHNIPYKWTAP 356 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCP 839 E L G ST D W FG L E+ G+ P S E +R+P P P Sbjct 357 EALSRG--HYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPP 414 Query 840 QLATLTSQCLTYEPTQRPSFRTIL 863 + L C +P QRP F+ + Sbjct 415 SVHKLMLTCWCRDPEQRPCFKALR 438 Score = 263 bits (671), Expect = 3e-76, Method: Composition-based stats. Identities = 88/301 (29%), Positives = 135/301 (45%), Gaps = 28/301 (9%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 P D + R LG G+FG+V + VA+K + Sbjct 169 PCRKHEPEPLPHWDDWERPREEFTLCRKLGSGYFGEVFEGLWKDR-----VQVAIKVISR 223 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--- 991 D H+ + EI ++ L H+HI+ + ++ E + GSL + L Sbjct 224 DNLL-HQQMLQSEIQAMKKLRHKHILALYAVVSVGD--PVYIITELMAKGSLLELLRDSD 280 Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 + +++LL A Q+ EGM YL +Q+YIHRDLAARN+L+ + L K+GDFGLA+ + E Sbjct 281 EKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKED 340 Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111 + D + P W APE L + SDVWSFG+ L+E+ + Sbjct 341 ---VYLSHDHNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQ------------ 385 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + M+ ++ G R+P P +CP V+ LM CW + RP F+ L L + Sbjct 386 --VPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSS 443 Query 1172 V 1172 Sbjct 444 F 444 >sp|Q91735|EPHB3_XENLA Ephrin type-B receptor 3 OS=Xenopus laevis OX=8355 GN=ephb3 PE=2 SV=1 Length=974 Score = 287 bits (735), Expect = 3e-80, Method: Composition-based stats. Identities = 79/325 (24%), Positives = 145/325 (45%), Gaps = 21/325 (6%) Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911 + + + + ++ + ++ +K +G G FG+V Sbjct 564 DSESEYTEKLQQYMVPGMKLYIDPFTYEDPNEAVRDFAKEIDISCVKIEEVIGAGEFGEV 623 Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 + VA+K LKA Q R + E I+ H +II+ +G Sbjct 624 CRGKLKQAGRRE-QFVAIKTLKAGYTEQQRRDFLGEASIMGQFDHPNIIRLEGVVTRS-- 680 Query 972 KSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029 + + ++ E++ G+L +L + + QL+ + I GM YL +Y+HRDLAARN+ Sbjct 681 RPVMILTEFMENGALDSFLRMNDGQFTVIQLVGILRGIASGMKYLSEMNYVHRDLAARNI 740 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 L++++ + K+ DFGL++ + Y G P+ W APE + KF ASDVWS+ Sbjct 741 LVNSNLVCKVSDFGLSRFLENSRSDPTYTSALGGKIPIRWTAPEAISYRKFTSASDVWSY 800 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 G+ ++E++++ + M+ + +E+ RLP P CP ++ L Sbjct 801 GIVMWEVMSYGER--------------PYWDMSNQDVINAIEQDYRLPPPMDCPSALHQL 846 Query 1148 MKNCWETEASFRPTFENLIPILKTV 1172 M +CW + + RP F ++ L + Sbjct 847 MLDCWLRDRNLRPKFSQIVSSLDKL 871 Score = 265 bits (678), Expect = 1e-72, Method: Composition-based stats. Identities = 72/293 (25%), Positives = 116/293 (40%), Gaps = 42/293 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G V G+L+ G +E V + Sbjct 602 KEIDISCVKIEEVIGAGEFGEVCRGKLKQAGR---------------------REQFVAI 640 Query 642 KVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L F AS+M Q H ++ + GV R +++TE++E+G LD +LR Sbjct 641 KTLKAGYTEQQRRDFLGEASIMGQFDHPNIIRLEGVVTRSRPVMILTEFMENGALDSFLR 700 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G + + + + +AS + YL N VH ++ RNIL+ ++ K+SD Sbjct 701 MNDGQFTVIQLVGILRGIASGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 753 Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ +IP W APE + ++A D W +G + E+ G Sbjct 754 GLSRFLENSRSDPTYTSALGGKIPIRWTAPEAIS--YRKFTSASDVWSYGIVMWEVMSYG 811 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTI 862 E P S + + ++ +RLP P CP L L C + RP F I Sbjct 812 ERPYWDMSNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWLRDRNLRPKFSQI 864 >sp|P22607|FGFR3_HUMAN Fibroblast growth factor receptor 3 OS=Homo sapiens OX=9606 GN=FGFR3 PE=1 SV=1 Length=806 Score = 284 bits (726), Expect = 3e-80, Method: Composition-based stats. Identities = 101/291 (35%), Positives = 146/291 (50%), Gaps = 38/291 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGWKQEIDILRTL-YHEH 958 LGEG FG+V + + VAVK LK D + S E+++++ + H++ Sbjct 478 LGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 537 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQLL 1001 II G C G L +++EY G+LR++L P + L+ Sbjct 538 IINLLGACTQGG--PLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLV 595 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 A Q+ GM YL +Q IHRDLAARNVL+ D ++KI DFGLA+ V +YY+ +G Sbjct 596 SCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDV-HNLDYYKKTTNG 654 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 PV W APE L + + + SDVWSFGV L+E+ T L G + V Sbjct 655 RLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFT--------------LGGSPYPGIPV 700 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 L +LL+ G R+ +P C ++Y +M+ CW S RPTF+ L+ L V Sbjct 701 EELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRV 751 Score = 240 bits (612), Expect = 4e-65, Method: Composition-based stats. Identities = 72/341 (21%), Positives = 126/341 (37%), Gaps = 60/341 (18%) Query 556 GETSNLIIMRGARAS----PRTLNLSQLSF-----HRVDQKEITQLSHLGQGTRTNVYEG 606 +SN ++R AR S P N+S+L + + +T LG+G V Sbjct 430 SMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQV--- 486 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV 665 + E + + + V +K+L D L +M + Sbjct 487 --------------VMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMI 532 Query 666 -SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG---------------HVPMA 709 H ++ + G C +G ++ EY G L +LR R + Sbjct 533 GKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFK 592 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA--- 766 + A Q+A + YL ++ +H ++ RN+L+ + +K++D G+ Sbjct 593 DLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNV-------MKIADFGLARDVHNL 645 Query 767 -LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 ++ R+P W+APE L + D W FG L EI G +P E Sbjct 646 DYYKKTTNGRLPVKWMAPEALFDRV--YTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEEL 703 Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 + HR+ P L + +C P+QRP+F+ + Sbjct 704 FKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQL 744 >sp|Q8JH64|BTK_CHICK Tyrosine-protein kinase BTK OS=Gallus gallus OX=9031 GN=BTK PE=1 SV=1 Length=657 Score = 280 bits (716), Expect = 4e-80, Method: Composition-based stats. Identities = 86/426 (20%), Positives = 162/426 (38%), Gaps = 63/426 (15%) Query 446 SIRDGIHGPLLEPFVQAKLRPE--DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLR 503 I + + + L+ E +G +++ STS + ++V +S +R Sbjct 274 EIYEWYSKNITRSQAEQLLKQEGKEGGFIVRDSTSKTGKYTVSVYAKSAVD---PQGMIR 330 Query 504 KFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLII 563 + + F ++ EL Q + L+ + Sbjct 331 HYVVCCTPQNQYYLAEKHLFNTIPELITYHQHN---SAGLISRLKYP------------V 375 Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 R +++P T L S+ +D K++T L LG G V G+ R Sbjct 376 SRHQKSAPSTAGLGYGSW-EIDPKDLTFLKELGTGQFGVVKYGKWRG------------- 421 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 + V +K++ F + A +M +SH L ++GVC + Sbjct 422 ------------QYNVAIKMIREGSMS-EDEFIDEAKVMMNLSHEKLVQLYGVCTKQRPI 468 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 ++TEY+ +G L +LR + A + + + + A+ YLE+K +H ++ RN L+ Sbjct 469 FIITEYMANGCLLNFLRETQRRFQPAELLEMCKDVCEAMEYLESKQFLHRDLAARNCLVN 528 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKW 798 G+ +K+SD G+ L E + W PE L + S+ D W Sbjct 529 DQGI-------VKVSDFGLSRYVLDDEYTSSMGSKFPVRWSPPEVLL--YSKFSSKSDVW 579 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 FG + E+ G+ P + + SE + RL P+ + ++ + C + +R Sbjct 580 SFGVLMWEVYSLGKMPYERFNNSETTEHVIQGLRLYRPQQASERVYAIMYSCWHEKAEER 639 Query 857 PSFRTI 862 P+F + Sbjct 640 PTFSAL 645 Score = 250 bits (639), Expect = 9e-70, Method: Composition-based stats. Identities = 84/288 (29%), Positives = 139/288 (48%), Gaps = 27/288 (9%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + L +++LG G FG V + + VA+K ++ G + E Sbjct 393 WEIDPKDLTFLKELGTGQFGVVKYGKWRGQYN-----VAIKMIRE--GSMSEDEFIDEAK 445 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQI 1007 ++ L HE +++ G C Q + + ++ EY+ G L ++L + A+LL + + Sbjct 446 VMMNLSHEKLVQLYGVCTKQ--RPIFIITEYMANGCLLNFLRETQRRFQPAELLEMCKDV 503 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 CE M YL ++ ++HRDLAARN L+++ +VK+ DFGL++ V + Y PV W Sbjct 504 CEAMEYLESKQFLHRDLAARNCLVNDQGIVKVSDFGLSRYVLDDE--YTSSMGSKFPVRW 561 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 PE L KF SDVWSFGV ++E+ + L + + TE Sbjct 562 SPPEVLLYSKFSSKSDVWSFGVLMWEVYS--------------LGKMPYERFNNSETTEH 607 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 + +G RL RP + VY +M +CW +A RPTF L+ + + ++ Sbjct 608 VIQGLRLYRPQQASERVYAIMYSCWHEKAEERPTFSALLGSIVDITDE 655 >sp|Q90344|EPHB2_COTJA Ephrin type-B receptor 2 OS=Coturnix japonica OX=93934 GN=EPHB2 PE=2 SV=1 Length=987 Score = 287 bits (735), Expect = 4e-80, Method: Composition-based stats. Identities = 81/325 (25%), Positives = 146/325 (45%), Gaps = 21/325 (6%) Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911 E T + T ++ + ++ +K + +G G FG+V Sbjct 577 EYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEV 636 Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 VA+K LK+ + R + E I+ H ++I +G Sbjct 637 CSGHLKLPGKRE-IFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSS- 694 Query 972 KSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029 + ++ E++ GSL +L ++ + QL+ + I GM YL +Y+HRDLAARN Sbjct 695 -PVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNT 753 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 L++++ + K+ DFGL++ + + Y G P+ W APE ++ KF ASDVWS+ Sbjct 754 LVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSY 813 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 G+ ++E++++ + MT + +E+ RLP P CP ++ L Sbjct 814 GIVMWEVMSYGER--------------PYWDMTNQDVINAIEQDYRLPPPMDCPNALHQL 859 Query 1148 MKNCWETEASFRPTFENLIPILKTV 1172 M +CW+ + + RP F ++ L + Sbjct 860 MLDCWQKDRNHRPKFGQIVNTLDKM 884 Score = 264 bits (675), Expect = 3e-72, Method: Composition-based stats. Identities = 69/304 (23%), Positives = 124/304 (41%), Gaps = 42/304 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G V G L++ G +E+ V + Sbjct 615 KEIDISCVKIEQVIGAGEFGEVCSGHLKLPGK---------------------REIFVAI 653 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + +++TE++E+G LD +LR Sbjct 654 KTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMIITEFMENGSLDSFLR 713 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL + N VH ++ RN L+ ++ K+SD Sbjct 714 QNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNTLVN-------SNLVCKVSDF 766 Query 761 GVGL---GALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ S I W APE + ++A D W +G + E+ G Sbjct 767 GLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQ--YRKFTSASDVWSYGIVMWEVMSYG 824 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P + + + ++ +RLP P CP L L C + RP F I+ L ++ Sbjct 825 ERPYWDMTNQDVINAIEQDYRLPPPMDCPNALHQLMLDCWQKDRNHRPKFGQIVNTLDKM 884 Query 870 QPHN 873 + Sbjct 885 IRNP 888 >sp|Q8JG38|FGFR2_DANRE Fibroblast growth factor receptor 2 OS=Danio rerio OX=7955 GN=fgfr2 PE=1 SV=1 Length=817 Score = 284 bits (726), Expect = 4e-80, Method: Composition-based stats. Identities = 122/433 (28%), Positives = 183/433 (42%), Gaps = 68/433 (16%) Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQC-LTYEPTQ 855 + G L+ + R+ ++K F + P + LT Q L + T Sbjct 380 IYCIGVFLIACMVVIVVVCRMRTSAKKPDFSSQ---------PAVHKLTKQIPLRRQVTV 430 Query 856 RPSFRTILRDLTRLQPHNL-----ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910 + + T L D D P F + L + LGEG FG+ Sbjct 431 SSDSSSSMSSSTPLVRITTRRSSAHDDPIPEYDLPEDPRWEFSRDKLTLGKPLGEGCFGQ 490 Query 911 VSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCC 966 V + + + VAVK LK D + S E+++++ + H++II G C Sbjct 491 VVMAEALGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGRHKNIINLLGAC 550 Query 967 EDQGEKSLQLVMEYVPLGSLRDYLP-----------------RHSIGLAQLLLFAQQICE 1009 G L +++EY G+LR+YL + L+ Q+ Sbjct 551 TQDG--PLYVIVEYASKGNLREYLRARRPPGMEYSYDIARVSDEPLTFKDLVSCTYQVAR 608 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 GM YL +Q IHRDLAARNVL+ ++KI DFGLA+ V +YY+ +G PV W A Sbjct 609 GMEYLASQKCIHRDLAARNVLVTESNVMKIADFGLARDV-HNIDYYKKTTNGRLPVKWMA 667 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE L + + + SDVWSFGV ++E+ T L G + V L +LL+ Sbjct 668 PEALFDRVYTHQSDVWSFGVLMWEIFT--------------LGGSPYPGIPVEELFKLLK 713 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH---------------E 1174 G R+ +P C E+Y +MK+CW +S RPTF+ L+ L + E Sbjct 714 EGHRMDKPANCTNELYMMMKDCWHAISSHRPTFKQLVEDLDRILTLATNEEYLDLCAPVE 773 Query 1175 KYQGQAPSVFSVC 1187 +Y P S C Sbjct 774 QYSPSFPDTRSSC 786 Score = 229 bits (585), Expect = 2e-61, Method: Composition-based stats. Identities = 63/322 (20%), Positives = 120/322 (37%), Gaps = 51/322 (16%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 +L + + ++T LG+G V + E + Sbjct 461 EYDLPEDPRWEFSRDKLTLGKPLGEGCFGQV-----------------VMAEALGIDKDK 503 Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690 + + V +K+L + L +M + H ++ + G C + ++ EY Sbjct 504 PKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGRHKNIINLLGACTQDGPLYVIVEYA 563 Query 691 EHGPLDVWLRRERGH-------------VPMAWKMVVA--QQLASALSYLENKNLVHGNV 735 G L +LR R P+ +K +V+ Q+A + YL ++ +H ++ Sbjct 564 SKGNLREYLRARRPPGMEYSYDIARVSDEPLTFKDLVSCTYQVARGMEYLASQKCIHRDL 623 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGAN 789 RN+L+ + +K++D G+ ++ R+P W+APE L Sbjct 624 AARNVLVTESNV-------MKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRV- 675 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847 + D W FG + EI G +P E + HR+ P +L + Sbjct 676 -YTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMKD 734 Query 848 CLTYEPTQRPSFRTILRDLTRL 869 C + RP+F+ ++ DL R+ Sbjct 735 CWHAISSHRPTFKQLVEDLDRI 756 >sp|O13147|EPHB3_DANRE Ephrin type-B receptor 3 (Fragment) OS=Danio rerio OX=7955 GN=ephb3 PE=2 SV=1 Length=500 Score = 275 bits (703), Expect = 4e-80, Method: Composition-based stats. Identities = 81/309 (26%), Positives = 135/309 (44%), Gaps = 23/309 (7%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD-PTNDGTGEMV 927 ++ + ++ +K +G G FG+V T V Sbjct 159 VKVYIDPFTYEDPNEAVHEFAREIDISCVKIEEVIGAGEFGEVCRGRLKQAGRKET--TV 216 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LKA R + E I+ H ++I +G + +V E++ G+L Sbjct 217 AIKTLKAGYTEHQRRDFLSEASIMGQFDHPNVIHLEGVLTRS--CPVLIVTEFMENGALD 274 Query 988 DYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L + QL+ + I GM YL +Y+HRDLAARNVL++++ + K+ DFGL+ Sbjct 275 SFLRLNDGRFTVTQLVGMLRGIAAGMKYLSDMNYVHRDLAARNVLVNSNLVCKVSDFGLS 334 Query 1046 KAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 + + + Y G P+ W APE + KF ASDVWS+G+ ++E+++ + Sbjct 335 RFLDDNSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSFGER--- 391 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163 M+ + +E+ RLP P CP ++ LM CW E + RP F Sbjct 392 -----------PYWDMSNQDVMNAVEQDYRLPPPMDCPAVLHQLMLECWVKERNMRPRFG 440 Query 1164 NLIPILKTV 1172 ++ L Sbjct 441 QIVSTLDKF 449 Score = 260 bits (665), Expect = 7e-75, Method: Composition-based stats. Identities = 73/292 (25%), Positives = 120/292 (41%), Gaps = 42/292 (14%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 +D + +G G V GRL+ G +E V +K Sbjct 181 EIDISCVKIEEVIGAGEFGEVCRGRLKQAGR---------------------KETTVAIK 219 Query 643 VLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 L + + F AS+M Q H ++ + GV R ++VTE++E+G LD +LR Sbjct 220 TLKAGYTEHQRRDFLSEASIMGQFDHPNVIHLEGVLTRSCPVLIVTEFMENGALDSFLRL 279 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 G + + + + +A+ + YL + N VH ++ RN+L+ ++ K+SD G Sbjct 280 NDGRFTVTQLVGMLRGIAAGMKYLSDMNYVHRDLAARNVLVN-------SNLVCKVSDFG 332 Query 762 VGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 + +IP W APE + ++A D W +G + E+ GE Sbjct 333 LSRFLDDNSSDPTYTSSLGGKIPIRWTAPEAIA--FRKFTSASDVWSYGIVMWEVMSFGE 390 Query 813 APLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862 P S + + ++ +RLP P CP L L +C E RP F I Sbjct 391 RPYWDMSNQDVMNAVEQDYRLPPPMDCPAVLHQLMLECWVKERNMRPRFGQI 442 >sp|Q0VBZ0|CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos taurus OX=9913 GN=CSK PE=2 SV=1 Length=450 Score = 273 bits (698), Expect = 5e-80, Method: Composition-based stats. Identities = 102/321 (32%), Positives = 154/321 (48%), Gaps = 33/321 (10%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915 TRL + + D + + LK ++ +G+G FG V L Sbjct 154 EHYTSDADGLCTRLIKPKVMEGTVAAQDEFFRSGWALNMKDLKLLQTIGKGEFGDVMLGD 213 Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 Y G VAVK +K D Q + E ++ L H ++++ G ++ + L Sbjct 214 YR------GNKVAVKCIKNDATAQ---AFLAEASVMTQLRHSNLVQLLGVIVEE-KSGLY 263 Query 976 LVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032 +V EY+ GSL DYL R +G LL F+ +CE M YL +++HRDLAARNVL+ Sbjct 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 D + K+ DFGL K E ++ G PV W APE L+E KF SDVWSFG+ L+ Sbjct 324 EDNVAKVSDFGLTK------EASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLW 377 Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152 E+ + + ++ + + +E+G ++ PD CP VY +MKNCW Sbjct 378 EIYSFGR--------------VPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCW 423 Query 1153 ETEASFRPTFENLIPILKTVH 1173 +A+ RP+F L L+ + Sbjct 424 HLDAATRPSFLQLREQLERIK 444 Score = 259 bits (663), Expect = 4e-75, Method: Composition-based stats. Identities = 98/436 (22%), Positives = 166/436 (38%), Gaps = 70/436 (16%) Query 446 SIRDGIHGPLLEPFVQAKL-RPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 S+ HG + + L PE GL+L+ ST++P L V + DG + Sbjct 78 SLMPWFHGKITREQAERLLCPPETGLFLVRESTNYPGDYTLCV-----SCDGK----VEH 128 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + I ++ F ++ +L A C L + + + + Sbjct 129 YRIMYHASKLSID-EEVYFENLMQLVEHYTSD---ADGLCTRLIKPKVMEGTVAAQDEFF 184 Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 R ++ K++ L +G+G +V G R Sbjct 185 RSG--------------WALNMKDLKLLQTIGKGEFGDVMLGDYRGN------------- 217 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE-N 683 +V +K + A AF AS+M+Q+ H++L + GV V Sbjct 218 -------------KVAVKCIKNDAT--AQAFLAEASVMTQLRHSNLVQLLGVIVEEKSGL 262 Query 684 IMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +VTEY+ G L +LR R R + + + + A+ YLE N VH ++ RN+L+ Sbjct 263 YIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLV 322 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFG 801 + +A K+SD G+ A S ++ + + W APE L ST D W FG Sbjct 323 SEDNVA-------KVSDFGLTKEASSTQDTGKLPVKWTAPEALRE--KKFSTKSDVWSFG 373 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859 L EI G P + ++ +++ P+ P + + C + RPSF Sbjct 374 ILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPSF 433 Query 860 RTILRDLTRLQPHNLA 875 + L R++ H L Sbjct 434 LQLREQLERIKTHELH 449 >sp|P41240|CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo sapiens OX=9606 GN=CSK PE=1 SV=1 Length=450 Score = 273 bits (697), Expect = 6e-80, Method: Composition-based stats. Identities = 102/321 (32%), Positives = 154/321 (48%), Gaps = 33/321 (10%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915 TRL + + D + + LK ++ +G+G FG V L Sbjct 154 EHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGD 213 Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 Y G VAVK +K D Q + E ++ L H ++++ G ++ + L Sbjct 214 YR------GNKVAVKCIKNDATAQ---AFLAEASVMTQLRHSNLVQLLGVIVEE-KGGLY 263 Query 976 LVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032 +V EY+ GSL DYL R +G LL F+ +CE M YL +++HRDLAARNVL+ Sbjct 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 D + K+ DFGL K E ++ G PV W APE L+E KF SDVWSFG+ L+ Sbjct 324 EDNVAKVSDFGLTK------EASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLW 377 Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152 E+ + + ++ + + +E+G ++ PD CP VY +MKNCW Sbjct 378 EIYSFGR--------------VPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCW 423 Query 1153 ETEASFRPTFENLIPILKTVH 1173 +A+ RP+F L L+ + Sbjct 424 HLDAAMRPSFLQLREQLEHIK 444 Score = 261 bits (666), Expect = 1e-75, Method: Composition-based stats. Identities = 100/436 (23%), Positives = 166/436 (38%), Gaps = 70/436 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRP-EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 S+ HG + + L P E GL+L+ ST++P L V + DG + Sbjct 78 SLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCV-----SCDGK----VEH 128 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + I ++ F ++ +L A C L + +M Sbjct 129 YRIMYHASKLSID-EEVYFENLMQLVEHYTSD---ADGLCTRLIKP-----------KVM 173 Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 G A+ S ++ KE+ L +G+G +V G R Sbjct 174 EGTVAAQDEF---YRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGN------------- 217 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV-CVRGPEN 683 +V +K + A AF AS+M+Q+ H++L + GV Sbjct 218 -------------KVAVKCIKNDAT--AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGL 262 Query 684 IMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +VTEY+ G L +LR R R + + + + A+ YLE N VH ++ RN+L+ Sbjct 263 YIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLV 322 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFG 801 + +A K+SD G+ A S ++ + + W APE L ST D W FG Sbjct 323 SEDNVA-------KVSDFGLTKEASSTQDTGKLPVKWTAPEALRE--KKFSTKSDVWSFG 373 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859 L EI G P + ++ +++ P+ P + + C + RPSF Sbjct 374 ILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSF 433 Query 860 RTILRDLTRLQPHNLA 875 + L ++ H L Sbjct 434 LQLREQLEHIKTHELH 449 >sp|P22182|FGFR1_XENLA Fibroblast growth factor receptor 1 OS=Xenopus laevis OX=8355 GN=fgfr1 PE=1 SV=1 Length=812 Score = 283 bits (724), Expect = 7e-80, Method: Composition-based stats. Identities = 105/335 (31%), Positives = 157/335 (47%), Gaps = 45/335 (13%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---EMVAVKALKADCG 937 + P + L + LGEG FG+V + + VAVK LK+D Sbjct 456 EYELPEDPRWEVARDRLILGKPLGEGCFGQVVMAEAIGLDKEKPNKVTKVAVKMLKSDAS 515 Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-- 994 + S E+++++ + H++II G C G L +++EY G+LR+YL Sbjct 516 EKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYTSKGNLREYLRARRPP 573 Query 995 ---------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI Sbjct 574 AMEYCYNPTCVPDQLLSFKDLVSCAYQVARGMDYLASKKCIHRDLAARNVLVTEDNIMKI 633 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T Sbjct 634 ADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--- 689 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L G + + L +LL+ G R+ +P C E+Y +MK+CW S R Sbjct 690 -----------LGGSPYPGVPMEELFKLLKEGHRMDKPTNCTNELYMMMKDCWHAMPSQR 738 Query 1160 PTFENLIPILKTV------HEKYQGQAP-SVFSVC 1187 PTF L+ L + E P + +S C Sbjct 739 PTFNQLVEDLDRILALSSNQEYLDLSMPVNQYSPC 773 Score = 235 bits (600), Expect = 2e-63, Method: Composition-based stats. Identities = 67/362 (19%), Positives = 119/362 (33%), Gaps = 51/362 (14%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 L + V + + LG+G V + E + Sbjct 455 SEYELPEDPRWEVARDRLILGKPLGEGCFGQV-----------------VMAEAIGLDKE 497 Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689 + +V +K+L + L +M + H ++ + G C + ++ EY Sbjct 498 KPNKVTKVAVKMLKSDASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 557 Query 690 VEHGPLDVWLRRERGH---------------VPMAWKMVVAQQLASALSYLENKNLVHGN 734 G L +LR R + + A Q+A + YL +K +H + Sbjct 558 TSKGNLREYLRARRPPAMEYCYNPTCVPDQLLSFKDLVSCAYQVARGMDYLASKKCIHRD 617 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788 + RN+L+ + +K++D G+ ++ R+P W+APE L Sbjct 618 LAARNVLVTEDNI-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRI 670 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846 + D W FG L EI G +P E + HR+ P +L + Sbjct 671 --YTHQSDVWSFGVLLWEIFTLGGSPYPGVPMEELFKLLKEGHRMDKPTNCTNELYMMMK 728 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906 C P+QRP+F ++ DL R+ + F + Sbjct 729 DCWHAMPSQRPTFNQLVEDLDRILALSSNQEYLDLSMPVNQYSPCFPDTRSSTCSSGEDS 788 Query 907 HF 908 F Sbjct 789 MF 790 >sp|P32577|CSK_RAT Tyrosine-protein kinase CSK OS=Rattus norvegicus OX=10116 GN=Csk PE=1 SV=1 Length=450 Score = 273 bits (697), Expect = 7e-80, Method: Composition-based stats. Identities = 103/321 (32%), Positives = 154/321 (48%), Gaps = 33/321 (10%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915 TRL + + D + + LK ++ +G+G FG V L Sbjct 154 EHYTTDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGD 213 Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 Y G VAVK +K D Q + E ++ L H ++++ G ++ + L Sbjct 214 YR------GNKVAVKCIKNDATAQ---AFLAEASVMTQLRHSNLVQLLGVIVEE-KGGLY 263 Query 976 LVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032 +V EY+ GSL DYL R +G LL F+ +CE M YL +++HRDLAARNVL+ Sbjct 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 D + K+ DFGL K E ++ G PV W APE L+E KF SDVWSFG+ L+ Sbjct 324 EDNVAKVSDFGLTK------EASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLW 377 Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152 E+ + + ++ + + +E+G ++ PD CP VY +MKNCW Sbjct 378 EIYSFGR--------------VPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYDVMKNCW 423 Query 1153 ETEASFRPTFENLIPILKTVH 1173 +A+ RPTF L L+ + Sbjct 424 HLDAATRPTFLQLREQLEHIR 444 Score = 262 bits (669), Expect = 4e-76, Method: Composition-based stats. Identities = 98/436 (22%), Positives = 165/436 (38%), Gaps = 70/436 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRP-EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 S+ HG + + L P E GL+L+ ST++P L V+ + K Sbjct 78 SLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASK 137 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 I+++ F ++ +L A C L + +M Sbjct 138 LSIDEE----------VYFENLMQLVEHYTTD---ADGLCTRLIKP-----------KVM 173 Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 G A+ S ++ KE+ L +G+G +V G R Sbjct 174 EGTVAAQDEF---YRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGN------------- 217 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV-CVRGPEN 683 +V +K + A AF AS+M+Q+ H++L + GV Sbjct 218 -------------KVAVKCIKNDAT--AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGL 262 Query 684 IMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +VTEY+ G L +LR R R + + + + A+ YLE N VH ++ RN+L+ Sbjct 263 YIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLV 322 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFG 801 + +A K+SD G+ A S ++ + + W APE L ST D W FG Sbjct 323 SEDNVA-------KVSDFGLTKEASSTQDTGKLPVKWTAPEALRE--KKFSTKSDVWSFG 373 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859 L EI G P + ++ +++ P+ P + + C + RP+F Sbjct 374 ILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYDVMKNCWHLDAATRPTF 433 Query 860 RTILRDLTRLQPHNLA 875 + L ++ H L Sbjct 434 LQLREQLEHIRTHELH 449 >sp|P41241|CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus musculus OX=10090 GN=Csk PE=1 SV=2 Length=450 Score = 272 bits (696), Expect = 1e-79, Method: Composition-based stats. Identities = 103/321 (32%), Positives = 154/321 (48%), Gaps = 33/321 (10%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915 TRL + + D + + LK ++ +G+G FG V L Sbjct 154 EHYTTDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGD 213 Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 Y G VAVK +K D Q + E ++ L H ++++ G ++ + L Sbjct 214 YR------GNKVAVKCIKNDATAQ---AFLAEASVMTQLRHSNLVQLLGVIVEE-KGGLY 263 Query 976 LVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032 +V EY+ GSL DYL R +G LL F+ +CE M YL +++HRDLAARNVL+ Sbjct 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVS 323 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 D + K+ DFGL K E ++ G PV W APE L+E KF SDVWSFG+ L+ Sbjct 324 EDNVAKVSDFGLTK------EASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLW 377 Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152 E+ + + ++ + + +E+G ++ PD CP VY +MKNCW Sbjct 378 EIYSFGR--------------VPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCW 423 Query 1153 ETEASFRPTFENLIPILKTVH 1173 +A+ RPTF L L+ + Sbjct 424 HLDAATRPTFLQLREQLEHIK 444 Score = 262 bits (669), Expect = 5e-76, Method: Composition-based stats. Identities = 98/436 (22%), Positives = 165/436 (38%), Gaps = 70/436 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRP-EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 S+ HG + + L P E GL+L+ ST++P L V+ + K Sbjct 78 SLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASK 137 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 I+++ F ++ +L A C L + +M Sbjct 138 LSIDEE----------VYFENLMQLVEHYTTD---ADGLCTRLIKP-----------KVM 173 Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 G A+ S ++ KE+ L +G+G +V G R Sbjct 174 EGTVAAQDEF---YRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGN------------- 217 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV-CVRGPEN 683 +V +K + A AF AS+M+Q+ H++L + GV Sbjct 218 -------------KVAVKCIKNDAT--AQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGL 262 Query 684 IMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +VTEY+ G L +LR R R + + + + A+ YLE N VH ++ RN+L+ Sbjct 263 YIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLV 322 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFG 801 + +A K+SD G+ A S ++ + + W APE L ST D W FG Sbjct 323 SEDNVA-------KVSDFGLTKEASSTQDTGKLPVKWTAPEALRE--KKFSTKSDVWSFG 373 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859 L EI G P + ++ +++ P+ P + + C + RP+F Sbjct 374 ILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPTF 433 Query 860 RTILRDLTRLQPHNLA 875 + L ++ H L Sbjct 434 LQLREQLEHIKTHELH 449 >sp|Q498D6|FGFR4_RAT Fibroblast growth factor receptor 4 OS=Rattus norvegicus OX=10116 GN=Fgfr4 PE=1 SV=1 Length=800 Score = 282 bits (721), Expect = 1e-79, Method: Composition-based stats. Identities = 102/304 (34%), Positives = 149/304 (49%), Gaps = 38/304 (13%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE---MVAVKALKADCGPQHRSGWKQ 946 F + L + LGEG FG+V + + VAVK LK + + + Sbjct 458 WEFPRDRLVLGKPLGEGCFGQVVRAEALGMDSSRPDQTSTVAVKMLKDNASDKDLADLIS 517 Query 947 EIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-------------- 991 E+++++ + H++II G C +G L +++EY G+LR++L Sbjct 518 EMEMMKLIGRHKNIINLLGVCTQEG--PLYVIVEYAAKGNLREFLRARRPPGPDLSPDGP 575 Query 992 ---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ V Sbjct 576 RSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDDVMKIADFGLARGV 635 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 +YY+ +G PV W APE L + + + SDVWSFG+ L+E+ T Sbjct 636 HH-IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFT------------ 682 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 L G + V L LL G R+ RP CP E+Y LM+ CW S RPTF+ L+ Sbjct 683 --LGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRECWHAAPSQRPTFKQLVEA 740 Query 1169 LKTV 1172 L V Sbjct 741 LDKV 744 Score = 238 bits (606), Expect = 2e-64, Method: Composition-based stats. Identities = 66/315 (21%), Positives = 114/315 (36%), Gaps = 51/315 (16%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 +L+L + + LG+G V + E + Sbjct 449 SLDLPLDPLWEFPRDRLVLGKPLGEGCFGQV-----------------VRAEALGMDSSR 491 Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690 Q V +K+L + D L +M + H ++ + GVC + ++ EY Sbjct 492 PDQTSTVAVKMLKDNASDKDLADLISEMEMMKLIGRHKNIINLLGVCTQEGPLYVIVEYA 551 Query 691 EHGPLDVWLRRER---------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNV 735 G L +LR R G + + A Q+A + YLE++ +H ++ Sbjct 552 AKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDL 611 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGAN 789 RN+L+ +K++D G+ G + + + W+APE L Sbjct 612 AARNVLVTE-------DDVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRV- 663 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847 + D W FG L EI G +P E + HR+ P +L L + Sbjct 664 -YTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRE 722 Query 848 CLTYEPTQRPSFRTI 862 C P+QRP+F+ + Sbjct 723 CWHAAPSQRPTFKQL 737 >sp|P42680|TEC_HUMAN Tyrosine-protein kinase Tec OS=Homo sapiens OX=9606 GN=TEC PE=1 SV=2 Length=631 Score = 278 bits (710), Expect = 1e-79, Method: Composition-based stats. Identities = 87/428 (20%), Positives = 162/428 (38%), Gaps = 66/428 (15%) Query 460 VQAKLRPE--DGLYLIHWSTSHPYRLILTVAQR--SQAPDGMQSLRLRKFPIEQQDGAFV 515 + LR E +G +++ S S P +++ + + G + +++ + Sbjct 257 AEQLLRSEDKEGGFMVRDS-SQPGLYTVSLYTKFGGEGSSGFRHYHIKE--TTTSPKKYY 313 Query 516 LEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLN 575 L +F S+ E+ + A LR + + +P T Sbjct 314 L-AEKHAFGSIPEIIEYHKHN---AAGLVTRLRYP------------VSVKGKNAPTTAG 357 Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 S ++ E+T + LG G V G+ R Sbjct 358 FSY-EKWEINPSELTFMRELGSGLFGVVRLGKWRA------------------------- 391 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 + +V +K + F E A +M +++H L ++GVC + +VTE++E G L Sbjct 392 QYKVAIKAIREGAM-CEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCL 450 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +LR+ +GH + + Q + + YLE + +H ++ RN L++ G+ + Sbjct 451 LNFLRQRQGHFSRDVLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGV-------V 503 Query 756 KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K+SD G+ L + + W PE + S+ D W FG + E+ + Sbjct 504 KVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVF--NYSRFSSKSDVWSFGVLMWEVFTE 561 Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 G P + + E R HRL P+ + + + +C +P RPSF +LR + Sbjct 562 GRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDE 621 Query 869 LQPHNLAD 876 L Sbjct 622 LVECEETF 629 Score = 254 bits (650), Expect = 2e-71, Method: Composition-based stats. Identities = 86/292 (29%), Positives = 136/292 (47%), Gaps = 27/292 (9%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 + + + L +R+LG G FG V L + VA+KA++ G + Sbjct 358 FSYEKWEINPSELTFMRELGSGLFGVVRLGKWRAQYK-----VAIKAIRE--GAMCEEDF 410 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLL 1002 +E ++ L H +++ G C Q K + +V E++ G L ++L + LL Sbjct 411 IEEAKVMMKLTHPKLVQLYGVCTQQ--KPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLS 468 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 Q +CEGM YL +IHRDLAARN L+ +VK+ DFG+A+ V + + Y Sbjct 469 MCQDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLD--DQYTSSSGAK 526 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 PV W PE +F SDVWSFGV ++E+ T + + T Sbjct 527 FPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGR--------------MPFEKYTNY 572 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + ++ RG RL +P VY +M CW+ + RP+FE+L+ + + E Sbjct 573 EVVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLRTIDELVE 624 >sp|Q91288|FGFR4_PLEWA Fibroblast growth factor receptor 4 OS=Pleurodeles waltl OX=8319 GN=FGFR4 PE=2 SV=1 Length=822 Score = 282 bits (722), Expect = 2e-79, Method: Composition-based stats. Identities = 105/350 (30%), Positives = 159/350 (45%), Gaps = 38/350 (11%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 L Q + S +++R + D P F + L + L Sbjct 433 LMRQFSLESSSSGKSSTSLVRVTRLSSSCTPMLPGVLEFDLPLDSKWEFPRERLVLGKPL 492 Query 904 GEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGWKQEIDILRTL-YHEHI 959 GEG FG+V N + VA+K +K + S E+++++ + H++I Sbjct 493 GEGCFGQVVRAEAYGINKDQPDKAITVAIKIVKDKGTDKELSDLISEMELMKLMGKHKNI 552 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQLLL 1002 I G C G L +++EY G+LR++L P + L+ Sbjct 553 INLLGVCTQDG--PLYMIVEYASKGNLREFLRARRPPSPDYTFDMTKVPEEQLSFQDLVS 610 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 + Q+ GMAYL ++ IHRDLAARNVL+ + ++KI DFGLA+ V +YY+ +G Sbjct 611 CSYQVARGMAYLESKRCIHRDLAARNVLVTGENVMKIADFGLARGV-HDIDYYKKTSNGR 669 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 PV W APE L + + + SDVWSFGV +E+ T L G + V Sbjct 670 LPVKWMAPEALFDRVYTHQSDVWSFGVLTWEIFT--------------LGGSPYPGIPVE 715 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 L +LL G R+ +P C E+Y LM+ CW S RPTF+ L+ L + Sbjct 716 ELFKLLREGHRMDKPSNCTHELYMLMRECWHAAPSQRPTFKQLVETLDRI 765 Score = 233 bits (594), Expect = 1e-62, Method: Composition-based stats. Identities = 70/355 (20%), Positives = 124/355 (35%), Gaps = 51/355 (14%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 +L S ++ + LG+G V + E + Sbjct 470 EFDLPLDSKWEFPRERLVLGKPLGEGCFGQV-----------------VRAEAYGINKDQ 512 Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690 + + V +K++ D L LM + H ++ + GVC + M+ EY Sbjct 513 PDKAITVAIKIVKDKGTDKELSDLISEMELMKLMGKHKNIINLLGVCTQDGPLYMIVEYA 572 Query 691 EHGPLDVWLRRERGHVP---------------MAWKMVVAQQLASALSYLENKNLVHGNV 735 G L +LR R P + + Q+A ++YLE+K +H ++ Sbjct 573 SKGNLREFLRARRPPSPDYTFDMTKVPEEQLSFQDLVSCSYQVARGMAYLESKRCIHRDL 632 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGAN 789 RN+L+ + +K++D G+ G + + + W+APE L Sbjct 633 AARNVLVTGENV-------MKIADFGLARGVHDIDYYKKTSNGRLPVKWMAPEALFDRV- 684 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847 + D W FG EI G +P E + HR+ P +L L + Sbjct 685 -YTHQSDVWSFGVLTWEIFTLGGSPYPGIPVEELFKLLREGHRMDKPSNCTHELYMLMRE 743 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902 C P+QRP+F+ ++ L R+ + L ++ P D Sbjct 744 CWHAAPSQRPTFKQLVETLDRILATVAEEYLDLSMPFEQYSPACEDTTSTCSSDD 798 >sp|Q61851|FGFR3_MOUSE Fibroblast growth factor receptor 3 OS=Mus musculus OX=10090 GN=Fgfr3 PE=1 SV=1 Length=801 Score = 282 bits (721), Expect = 2e-79, Method: Composition-based stats. Identities = 100/306 (33%), Positives = 148/306 (48%), Gaps = 37/306 (12%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT---GEMVAVKALKADCGPQHRSGW 944 + L + LGEG FG+V + + VAVK LK D + S Sbjct 457 PKWELSRTRLTLGKPLGEGCFGQVVMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDLSDL 516 Query 945 KQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------------- 990 E+++++ + H++II G C G L +++EY G+LR++L Sbjct 517 VSEMEMMKMIGKHKNIINLLGACTQGG--PLYVLVEYAAKGNLREFLRARRPPGMDYSFD 574 Query 991 ----PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 P + L+ A Q+ GM YL +Q IHRDLAARNVL+ D ++KI DFGLA+ Sbjct 575 ACRLPEEQLTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLAR 634 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 V +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T S Sbjct 635 DV-HNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTPGGPS----- 688 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + V L +LL+ G R+ +P C ++Y +M+ CW S RPTF+ L+ Sbjct 689 --------PYPGIPVEELFKLLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTFKQLV 740 Query 1167 PILKTV 1172 L + Sbjct 741 EDLDRI 746 Score = 237 bits (605), Expect = 4e-64, Method: Composition-based stats. Identities = 79/362 (22%), Positives = 135/362 (37%), Gaps = 63/362 (17%) Query 545 FSLRRC--CLPQPGETSNLIIMRGARAS----PRTLNLSQLSF-----HRVDQKEITQLS 593 F L+R SN ++R AR S P N+S+L + + +T Sbjct 411 FPLKRQVSLESNSSMNSNTPLVRIARLSSGEGPVLANVSELELPADPKWELSRTRLTLGK 470 Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LG+G V + E + + + V +K+L D L Sbjct 471 PLGEGCFGQV-----------------VMAEAIGIDKDRTAKPVTVAVKMLKDDATDKDL 513 Query 654 -AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG------- 704 +M + H ++ + G C +G ++ EY G L +LR R Sbjct 514 SDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGMDYSF 573 Query 705 ---HVPMAWK-----MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +P + A Q+A + YL ++ +H ++ RN+L+ + +K Sbjct 574 DACRLPEEQLTCKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNV-------MK 626 Query 757 LSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICF- 809 ++D G+ ++ R+P W+APE L + D W FG L EI Sbjct 627 IADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRV--YTHQSDVWSFGVLLWEIFTP 684 Query 810 DGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 G +P E + HR+ P L + +C P+QRP+F+ ++ DL Sbjct 685 GGPSPYPGIPVEELFKLLKEGHRMDKPASCTHDLYMIMRECWHAVPSQRPTFKQLVEDLD 744 Query 868 RL 869 R+ Sbjct 745 RI 746 >sp|Q03364|FGFR2_XENLA Fibroblast growth factor receptor 2 OS=Xenopus laevis OX=8355 GN=fgfr2 PE=2 SV=1 Length=813 Score = 282 bits (721), Expect = 2e-79, Method: Composition-based stats. Identities = 101/320 (32%), Positives = 154/320 (48%), Gaps = 38/320 (12%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVK 930 + + P F + L + LGEG FG+V + + + VAVK Sbjct 448 MPLANVSEYELPHDPMWEFSRDKLTLGKPLGEGCFGQVVMAEALGIDKERPKESVTVAVK 507 Query 931 ALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 LK + + + E+++++ + H++II G C G +L +++EY G+LR Y Sbjct 508 MLKDNATEKDLADLVSEMEMMKMIGKHKNIINLLGACTQGG--TLYVIVEYAAKGNLRQY 565 Query 990 L-----------------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032 L P + L+ QI GM YL +Q IHRDLAARNVL+ Sbjct 566 LRARRPLEMEYSFDVTRVPDEQMTFKDLVSCTYQIARGMEYLASQKCIHRDLAARNVLVT 625 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 + ++KI DFGLA+ V +YY+ +G PV W APE L + + + SDVWSFGV ++ Sbjct 626 ENNVMKIADFGLARDV-NNIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMW 684 Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152 E+ T L G + V L +LL+ G R+ +P C E+Y +M++CW Sbjct 685 EIFT--------------LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCW 730 Query 1153 ETEASFRPTFENLIPILKTV 1172 S RPTF+ L+ L + Sbjct 731 HAIPSHRPTFKQLVEDLDRI 750 Score = 231 bits (589), Expect = 6e-62, Method: Composition-based stats. Identities = 63/326 (19%), Positives = 118/326 (36%), Gaps = 51/326 (16%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 A+ L + ++T LG+G V + E + Sbjct 451 ANVSEYELPHDPMWEFSRDKLTLGKPLGEGCFGQV-----------------VMAEALGI 493 Query 629 PGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMV 686 + + V +K+L + + L +M + H ++ + G C +G ++ Sbjct 494 DKERPKESVTVAVKMLKDNATEKDLADLVSEMEMMKMIGKHKNIINLLGACTQGGTLYVI 553 Query 687 TEYVEHGPLDVWLRRERG---------------HVPMAWKMVVAQQLASALSYLENKNLV 731 EY G L +LR R + + Q+A + YL ++ + Sbjct 554 VEYAAKGNLRQYLRARRPLEMEYSFDVTRVPDEQMTFKDLVSCTYQIARGMEYLASQKCI 613 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLP 785 H ++ RN+L+ + +K++D G+ ++ R+P W+APE L Sbjct 614 HRDLAARNVLVTENNV-------MKIADFGLARDVNNIDYYKKTSNGRLPVKWMAPEALF 666 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLAT 843 + D W FG + EI G +P E + HR+ P +L Sbjct 667 DRV--YTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYM 724 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRL 869 + C P+ RP+F+ ++ DL R+ Sbjct 725 MMRDCWHAIPSHRPTFKQLVEDLDRI 750 >sp|Q91286|FGFR2_PLEWA Fibroblast growth factor receptor 2 OS=Pleurodeles waltl OX=8319 GN=FGFR2 PE=2 SV=1 Length=824 Score = 281 bits (720), Expect = 3e-79, Method: Composition-based stats. Identities = 100/313 (32%), Positives = 150/313 (48%), Gaps = 38/313 (12%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE---MVAVKALKADCG 937 + P + + L + LGEG FG+V + + + VAVK LK D Sbjct 462 EYELPEDPKWEYPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDRPKDAVTVAVKMLKDDAT 521 Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990 + S E+++++ + H++II G C G L +++EY G+LR+YL Sbjct 522 EKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLYVIVEYASKGNLREYLRTRRPP 579 Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P + L+ Q+ GM YL +Q IHRDLAARNVL+ ++KI Sbjct 580 GMEYSFDIFRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTETNVIKI 639 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLA+ + +YY+ +G PV W APE L + + SDVWSFGV ++E+ T Sbjct 640 ADFGLARDI-NNIDYYKKTTNGRLPVKWMAPEALFDRVYTLQSDVWSFGVLMWEIFT--- 695 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L G + V L +LL+ G R+ +P C E+Y +M +CW S R Sbjct 696 -----------LGGSPYPGIPVEELFKLLKEGHRMVKPGNCTNELYTMMTDCWRAVPSQR 744 Query 1160 PTFENLIPILKTV 1172 PTF+ L+ L + Sbjct 745 PTFKQLVEDLDRI 757 Score = 232 bits (592), Expect = 2e-62, Method: Composition-based stats. Identities = 66/356 (19%), Positives = 121/356 (34%), Gaps = 51/356 (14%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 L + + ++T LG+G V + E + Sbjct 461 SEYELPEDPKWEYPRDKLTLGKPLGEGCFGQV-----------------VMAEAVGIDKD 503 Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689 + V +K+L + L +M + H ++ + G C + ++ EY Sbjct 504 RPKDAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 563 Query 690 VEHGPLDVWLRRERG----------HVPMAW-----KMVVAQQLASALSYLENKNLVHGN 734 G L +LR R +P + QLA + YL ++ +H + Sbjct 564 ASKGNLREYLRTRRPPGMEYSFDIFRIPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD 623 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788 + RN+L+ + IK++D G+ ++ R+P W+APE L Sbjct 624 LAARNVLVTETNV-------IKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRV 676 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846 + D W FG + EI G +P E + HR+ P +L T+ + Sbjct 677 --YTLQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMVKPGNCTNELYTMMT 734 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902 C P+QRP+F+ ++ DL R+ + + + Sbjct 735 DCWRAVPSQRPTFKQLVEDLDRILTQTTNEEYLDLNNPLEPYSPSYPDTRSSCSFG 790 >sp|Q07494|EPHB1_CHICK Ephrin type-B receptor 1 (Fragment) OS=Gallus gallus OX=9031 GN=EPHB1 PE=2 SV=2 Length=984 Score = 285 bits (728), Expect = 3e-79, Method: Composition-based stats. Identities = 78/308 (25%), Positives = 142/308 (46%), Gaps = 21/308 (7%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 ++ + ++ ++K +G G FG+V VA Sbjct 591 MKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKRE-IYVA 649 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LKA + R + E I+ H +II+ +G + + ++ E++ G+L Sbjct 650 IKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGALDS 707 Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 +L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++ Sbjct 708 FLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 767 Query 1047 AVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 + + Y G PV W APE + KF ASDVWS+G+ ++E+++ + Sbjct 768 YLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGER---- 823 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 M+ + +E+ RLP P CP ++ LM +CW+ + + RP Sbjct 824 ----------PYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNTRPRLAE 873 Query 1165 LIPILKTV 1172 ++ L + Sbjct 874 IVNTLDKM 881 Score = 278 bits (711), Expect = 6e-77, Method: Composition-based stats. Identities = 80/363 (22%), Positives = 139/363 (38%), Gaps = 46/363 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G VY+GRL++ G +E+ V + Sbjct 612 KEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGK---------------------REIYVAI 650 Query 642 KVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L F AS+M Q H ++ + GV + +++TE++E+G LD +LR Sbjct 651 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 710 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD Sbjct 711 QNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVN-------SNLVCKVSDF 763 Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ +IP W APE + ++A D W +G + E+ G Sbjct 764 GLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSFG 821 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P S + + ++ +RLP P CP L L C + RP I+ L ++ Sbjct 822 ERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNTRPRLAEIVNTLDKM 881 Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG----E 925 + + + S P + E V + Y G + Sbjct 882 IRNPASLKTVATITAVPSQPLLDRSIPDFTAFTSVEDWLSAVKMSQYRDNFLSAGFTSLQ 941 Query 926 MVA 928 +VA Sbjct 942 LVA 944 >sp|P51451|BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo sapiens OX=9606 GN=BLK PE=1 SV=3 Length=505 Score = 272 bits (696), Expect = 4e-79, Method: Composition-based stats. Identities = 79/403 (20%), Positives = 150/403 (37%), Gaps = 69/403 (17%) Query 469 GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRE 528 G +LI S ++ L+V + + ++ + I D +FPS++ Sbjct 146 GSFLIRESETNKGAFSLSVKDVTTQGE-----LIKHYKIRCLDEGGYYISPRITFPSLQA 200 Query 529 LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKE 588 L C L C+ R +P+ + ++ Sbjct 201 LVQHYSKKG---DGLCQRLTLPCV---------------RPAPQNPWAQ--DEWEIPRQS 240 Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 + + LG G V+ G + ++V +K L Sbjct 241 LRLVRKLGSGQFGEVWMGYYKNN-------------------------MKVAIKTLKEGT 275 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVP 707 AF A++M + H L ++ V + +VTEY+ G L +L+ + G + Sbjct 276 MSP-EAFLGEANVMKALQHERLVRLYAVVTK-EPIYIVTEYMARGCLLDFLKTDEGSRLS 333 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--- 764 + + ++ Q+A ++Y+E N +H ++ NIL++ + K++D G+ Sbjct 334 LPRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSE-------ALCCKIADFGLARIID 386 Query 765 -GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 ++E I W APE + G + D W FG L+E+ G P S E Sbjct 387 SEYTAQEGAKFPIKWTAPEAIHFGV--FTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEV 444 Query 824 EHFYQRQHRL--PEPSCPQLAT-LTSQCLTYEPTQRPSFRTIL 863 +R +R+ P+ P+L + ++C P +RP+F + Sbjct 445 IRNLERGYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEFLQ 487 Score = 268 bits (686), Expect = 9e-78, Method: Composition-based stats. Identities = 97/315 (31%), Positives = 148/315 (47%), Gaps = 31/315 (10%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 Q L V + A D ++ L+ +R LG G FG+V + Y VA Sbjct 213 CQRLTLPCVRPAPQNPWAQDEWEIPRQSLRLVRKLGSGQFGEVWMGYYK-----NNMKVA 267 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LK G + E ++++ L HE +++ ++ + +V EY+ G L D Sbjct 268 IKTLKE--GTMSPEAFLGEANVMKALQHERLVRLYAVV---TKEPIYIVTEYMARGCLLD 322 Query 989 YLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L + L +L+ + QI EGMAY+ + IHRDL A N+L+ KI DFGLA Sbjct 323 FLKTDEGSRLSLPRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLA 382 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + Y +E P+ W APE + F +DVWSFGV L E++T+ Sbjct 383 RII---DSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLMEVVTYGR------ 433 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH-LMKNCWETEASFRPTFEN 1164 + M+ + LERG R+PRPD CP E+Y ++ CW + RPTFE Sbjct 434 --------VPYPGMSNPEVIRNLERGYRMPRPDTCPPELYRGVIAECWRSRPEERPTFEF 485 Query 1165 LIPILKTVHEKYQGQ 1179 L +L+ + + Q Sbjct 486 LQSVLEDFYTATERQ 500 >sp|P24604|TEC_MOUSE Tyrosine-protein kinase Tec OS=Mus musculus OX=10090 GN=Tec PE=1 SV=2 Length=630 Score = 276 bits (706), Expect = 4e-79, Method: Composition-based stats. Identities = 88/428 (21%), Positives = 159/428 (37%), Gaps = 66/428 (15%) Query 460 VQAKLRPE--DGLYLIHWSTSHPYRLILTVAQR--SQAPDGMQSLRLRKFPIEQQDGAFV 515 + LR E +G +++ S S P +++ + + G + +++ + Sbjct 256 AEQLLRTEDKEGGFMVRDS-SQPGLYTVSLYTKFGGEGSSGFRHYHIKE--TATSPKKYY 312 Query 516 LEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLN 575 L +F S+ E+ + A LR + + +P T Sbjct 313 L-AEKHAFGSIPEIIEYHKHN---AAGLVTRLRYP------------VSTKGKNAPTTAG 356 Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 S ++ E+T + LG G V G+ R Sbjct 357 FSY-DKWEINPSELTFMRELGSGLFGVVRLGKWRA------------------------- 390 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 + +V +K + F E A +M +++H L ++GVC + +VTE++E G L Sbjct 391 QYKVAIKAIREGAM-CEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCL 449 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +LR+ +GH + + Q + + YLE + +H ++ RN L+ G+ + Sbjct 450 LNFLRQRQGHFSRDMLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGV-------V 502 Query 756 KLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K+SD G+ L + + W PE + S+ D W FG + EI + Sbjct 503 KVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVF--NYSRFSSKSDVWSFGVLMWEIFTE 560 Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 G P + + E R HRL P+ + L + +C P RPS +LR + Sbjct 561 GRMPFEKNTNYEVVTMVTRGHRLHRPKLATKYLYEVMLRCWQERPEGRPSLEDLLRTIDE 620 Query 869 LQPHNLAD 876 L Sbjct 621 LVECEETF 628 Score = 254 bits (649), Expect = 2e-71, Method: Composition-based stats. Identities = 86/292 (29%), Positives = 135/292 (46%), Gaps = 27/292 (9%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 + D + L +R+LG G FG V L + VA+KA++ G + Sbjct 357 FSYDKWEINPSELTFMRELGSGLFGVVRLGKWRAQYK-----VAIKAIRE--GAMCEEDF 409 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLL 1002 +E ++ L H +++ G C Q K + +V E++ G L ++L + LL Sbjct 410 IEEAKVMMKLTHPKLVQLYGVCTQQ--KPIYIVTEFMERGCLLNFLRQRQGHFSRDMLLS 467 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 Q +CEGM YL +IHRDLAARN L++ +VK+ DFG+A+ V + + Y Sbjct 468 MCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGVVKVSDFGMARYVLD--DQYTSSSGAK 525 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 PV W PE +F SDVWSFGV ++E+ T + + T Sbjct 526 FPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTEGR--------------MPFEKNTNY 571 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + ++ RG RL RP +Y +M CW+ RP+ E+L+ + + E Sbjct 572 EVVTMVTRGHRLHRPKLATKYLYEVMLRCWQERPEGRPSLEDLLRTIDELVE 623 >sp|Q90Z00|FGR1A_DANRE Fibroblast growth factor receptor 1-A OS=Danio rerio OX=7955 GN=fgfr1a PE=1 SV=2 Length=810 Score = 281 bits (718), Expect = 4e-79, Method: Composition-based stats. Identities = 102/312 (33%), Positives = 154/312 (49%), Gaps = 38/312 (12%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---EMVAVKALKADCG 937 + P + L + LGEG FG+V + + VAVK LK+D Sbjct 449 EYELPQDPRWEVQRDRLVLGKPLGEGCFGQVMMAEAMGMDKEKPNRITKVAVKMLKSDAT 508 Query 938 PQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------ 990 + S E+++++ + H++II G C G L +++E+ G+LR+YL Sbjct 509 EKDLSDLISEMEMMKIIGKHKNIINLLGACTQDG--PLYVIVEFAAKGNLREYLRVRRPP 566 Query 991 -----------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 P ++ + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI Sbjct 567 GMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKI 626 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLA+ + +YY+ +G PV W APE L + + + SDVWSFGV L+E+ T Sbjct 627 ADFGLARDIHH-IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFT--- 682 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L G + V L +LL+ G R+ RP C E+Y +M++CW S R Sbjct 683 -----------LGGSPYPGVPVEELFKLLKEGHRMDRPSTCTHELYMMMRDCWHAVPSQR 731 Query 1160 PTFENLIPILKT 1171 PTF+ L+ L Sbjct 732 PTFKQLVEDLDR 743 Score = 233 bits (594), Expect = 1e-62, Method: Composition-based stats. Identities = 63/316 (20%), Positives = 113/316 (36%), Gaps = 51/316 (16%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 L Q V + + LG+G V M E + Sbjct 448 SEYELPQDPRWEVQRDRLVLGKPLGEGCFGQV-----------------MMAEAMGMDKE 490 Query 632 DRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEY 689 + +V +K+L + L +M + H ++ + G C + ++ E+ Sbjct 491 KPNRITKVAVKMLKSDATEKDLSDLISEMEMMKIIGKHKNIINLLGACTQDGPLYVIVEF 550 Query 690 VEHGPLDVWLRRERG---------------HVPMAWKMVVAQQLASALSYLENKNLVHGN 734 G L +LR R ++ + + A Q+A + YL +K +H + Sbjct 551 AAKGNLREYLRVRRPPGMEYCYNPDQVPVENMSIKDLVSCAYQVARGMEYLASKKCIHRD 610 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGA 788 + RN+L+ + +K++D G+ ++ R+P W+APE L Sbjct 611 LAARNVLVTEDNV-------MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRI 663 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846 + D W FG L EI G +P E + HR+ P +L + Sbjct 664 --YTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDRPSTCTHELYMMMR 721 Query 847 QCLTYEPTQRPSFRTI 862 C P+QRP+F+ + Sbjct 722 DCWHAVPSQRPTFKQL 737 >sp|P27450|CST_ARATH Probable serine/threonine-protein kinase CST OS=Arabidopsis thaliana OX=3702 GN=CST PE=1 SV=2 Length=419 Score = 269 bits (688), Expect = 4e-79, Method: Composition-based stats. Identities = 80/282 (28%), Positives = 139/282 (49%), Gaps = 15/282 (5%) Query 903 LGEGHFGKVSLYCYDPT-----NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LG+G FGKV D T G+G +VA+K L ++ Q + W+ E++ L L H Sbjct 92 LGQGGFGKVYRGWVDATTLAPSRVGSGMIVAIKRLNSE-SVQGFAEWRSEVNFLGMLSHR 150 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLH 1015 +++K G C + +K L LV E++P GSL +L R + G+A+LH Sbjct 151 NLVKLLGYCRE--DKELLLVYEFMPKGSLESHLFRRNDPFPWDLRIKIVIGAARGLAFLH 208 Query 1016 A--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + + I+RD A N+LLD++ K+ DFGLAK P + + V + APE + Sbjct 209 SLQREVIYRDFKASNILLDSNYDAKLSDFGLAKLGPADEKSH-VTTRIMGTYGYAAPEYM 267 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVL-RLTELLERG 1131 Y SDV++FGV L E++T + P L+ + +++ R+ +++++G Sbjct 268 ATGHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLVDWLRPELSNKHRVKQIMDKG 327 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + K E+ + +C E + RP + ++ +L+ + Sbjct 328 IKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEVLEHIQ 369 Score = 245 bits (625), Expect = 2e-70, Method: Composition-based stats. Identities = 83/395 (21%), Positives = 140/395 (35%), Gaps = 60/395 (15%) Query 554 QPGETSNLIIM-RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 Q + S II G L + + K S LGQG VY G + Sbjct 50 QFSDISTGIISDSGKLLESPNLKVYNFLDLKTATKNFKPDSMLGQGGFGKVYRGWV---- 105 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672 D L P R G + V +K L+ + + + +SH +L Sbjct 106 ----------DATTLAPSR-VGSGMIVAIKRLNSESVQGFAEWRSEVNFLGMLSHRNLVK 154 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN--KNL 730 + G C E ++V E++ G L+ L R P ++ + A L++L + + + Sbjct 155 LLGYCREDKELLLVYEFMPKGSLESHLFRRNDPFPWDLRIKIVIGAARGLAFLHSLQREV 214 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECL 784 ++ + NILL ++ KLSD G+ + E+ + + APE + Sbjct 215 IYRDFKASNILLD-------SNYDAKLSDFGLAKLGPADEKSHVTTRIMGTYGYAAPEYM 267 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-------QHRLPEPS 837 G L D + FG LLEI G ++ P +E +HR+ + Sbjct 268 ATG--HLYVKSDVFAFGVVLLEIM-TGLTAHNTKRPRGQESLVDWLRPELSNKHRVKQIM 324 Query 838 C------------PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885 ++A +T C+ +P RP + ++ L +Q N+ + + Sbjct 325 DKGIKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEVLEHIQGLNVVPNRSSTKQAV 384 Query 886 ASDPTVFHKRYLKKIRDL-------GEGHFGKVSL 913 A+ Y K L G FG V Sbjct 385 ANSSRSSPHHYRYKAGALGAERKRATPGRFGSVEK 419 >sp|Q5XF79|PBL18_ARATH Probable serine/threonine-protein kinase PBL18 OS=Arabidopsis thaliana OX=3702 GN=PBL18 PE=2 SV=1 Length=387 Score = 268 bits (685), Expect = 5e-79, Method: Composition-based stats. Identities = 94/331 (28%), Positives = 142/331 (43%), Gaps = 14/331 (4%) Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVS 912 P+ + T + + + + R K +GEG FG V Sbjct 40 PSYSNNSFTTSSWSNLTPRSEGELLPSPTLKAFTFNELKTATRNFKPNSMIGEGGFGCVY 99 Query 913 LYC-----YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 P+ G+G +VAVK LK++ G Q W E+ L L+H +++K G C Sbjct 100 KGWIGERSLSPSKPGSGMVVAVKKLKSE-GFQGHKEWLTEVHYLGRLHHMNLVKLIGYCL 158 Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQHYIHRDL 1024 + GEK L LV EY+P GSL ++L R I + A G+++LH I+RD Sbjct 159 E-GEKRL-LVYEYMPKGSLENHLFRRGAEPIPWKTRMKVAFSAARGLSFLHEAKVIYRDF 216 Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084 A N+LLD D K+ DFGLAKA P G + V + APE + + SDV Sbjct 217 KASNILLDVDFNAKLSDFGLAKAGPTGDRTH-VTTQVIGTQGYAAPEYIATGRLTSKSDV 275 Query 1085 WSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQMTVLR-LTELLERGERLPRPDKCPC 1142 +SFGV L ELL+ + L+ A + R + +++ P K C Sbjct 276 YSFGVVLLELLSGRPTLDKSKVGVERNLVDWAIPYLVDRRKVFRIMDTKLGGQYPHKGAC 335 Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 ++ C TE RP +++ L+ + Sbjct 336 AAANIALRCLNTEPKLRPDMADVLSTLQQLE 366 Score = 239 bits (611), Expect = 7e-69, Method: Composition-based stats. Identities = 75/361 (21%), Positives = 124/361 (34%), Gaps = 50/361 (14%) Query 556 GETSNL-IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 SNL G TL + + + S +G+G VY+G + Sbjct 50 SSWSNLTPRSEGELLPSPTLKAFTFNELKTATRNFKPNSMIGEGGFGCVYKGWIG----- 104 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 E L P + G + V +K L + + ++ H +L + Sbjct 105 ---------ERSLSPSKP-GSGMVVAVKKLKSEGFQGHKEWLTEVHYLGRLHHMNLVKLI 154 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHG 733 G C+ G + ++V EY+ G L+ L R +P +M VA A LS+L +++ Sbjct 155 GYCLEGEKRLLVYEYMPKGSLENHLFRRGAEPIPWKTRMKVAFSAARGLSFLHEAKVIYR 214 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGG 787 + NILL KLSD G+ + + + + APE + G Sbjct 215 DFKASNILLD-------VDFNAKLSDFGLAKAGPTGDRTHVTTQVIGTQGYAAPEYIATG 267 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR------------------ 829 L++ D + FG LLE+ +S+ E+ Sbjct 268 --RLTSKSDVYSFGVVLLELLSGRPTLDKSKVGVERNLVDWAIPYLVDRRKVFRIMDTKL 325 Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 + P A + +CL EP RP +L L +L+ + T N S Sbjct 326 GGQYPHKGACAAANIALRCLNTEPKLRPDMADVLSTLQQLETSSKKMGSTQNIVMSPSSH 385 Query 890 T 890 Sbjct 386 M 386 >sp|P41239|CSK_CHICK Tyrosine-protein kinase CSK OS=Gallus gallus OX=9031 GN=CSK PE=2 SV=1 Length=450 Score = 270 bits (691), Expect = 5e-79, Method: Composition-based stats. Identities = 102/323 (32%), Positives = 154/323 (48%), Gaps = 33/323 (10%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915 +RL + + D + + + LK ++ +G+G FG V L Sbjct 154 EHYTTDADGLCSRLIKPKVMEGTVAAQDEFSRSGWALNMKDLKLLQIIGKGEFGDVMLGD 213 Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 Y G VAVK +K D Q + E ++ L H ++++ G ++ + L Sbjct 214 YR------GNKVAVKCIKNDATAQ---AFLAEASVMTQLRHSNLVQLLGVIVEE-KSGLY 263 Query 976 LVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032 +V EY+ GSL DYL R +G LL F+ +CE M YL A +++HRDLAARNVL+ Sbjct 264 IVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEANNFVHRDLAARNVLVS 323 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 D + K+ DFGL K E ++ G PV W APE L+E KF SDVWSFG+ L+ Sbjct 324 EDNIAKVSDFGLTK------EASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLW 377 Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152 E+ + + ++ + + +E+G ++ PD CP VY +MK CW Sbjct 378 EIYSFGR--------------VPYPRIPLKDVVPRVEKGYKMDPPDGCPAIVYEVMKKCW 423 Query 1153 ETEASFRPTFENLIPILKTVHEK 1175 + RP+F L L + EK Sbjct 424 TLDPGHRPSFHQLREQLVHIKEK 446 Score = 260 bits (665), Expect = 2e-75, Method: Composition-based stats. Identities = 100/431 (23%), Positives = 168/431 (39%), Gaps = 70/431 (16%) Query 446 SIRDGIHGPLLEPFVQAKLRP-EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 S+ HG + + L P E GL+L+ ST++P L V+ + K Sbjct 78 SLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIIYSSSK 137 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 I+++ F ++ +L A C L + +M Sbjct 138 LSIDEE----------VYFENLMQLVEHYTTD---ADGLCSRLIKP-----------KVM 173 Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 G A+ + S ++ K++ L +G+G +V G R Sbjct 174 EGTVAAQDEFSRSG---WALNMKDLKLLQIIGKGEFGDVMLGDYRGN------------- 217 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE-N 683 +V +K + A AF AS+M+Q+ H++L + GV V Sbjct 218 -------------KVAVKCIKNDAT--AQAFLAEASVMTQLRHSNLVQLLGVIVEEKSGL 262 Query 684 IMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +VTEY+ G L +LR R R + + + + A+ YLE N VH ++ RN+L+ Sbjct 263 YIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEANNFVHRDLAARNVLV 322 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE-RIPWLAPECLPGGANSLSTAMDKWGFG 801 + +A K+SD G+ A S ++ + + W APE L ST D W FG Sbjct 323 SEDNIA-------KVSDFGLTKEASSTQDTGKLPVKWTAPEALRE--KKFSTKSDVWSFG 373 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQL-ATLTSQCLTYEPTQRPSF 859 L EI G P + ++ +++ P CP + + +C T +P RPSF Sbjct 374 ILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDPPDGCPAIVYEVMKKCWTLDPGHRPSF 433 Query 860 RTILRDLTRLQ 870 + L ++ Sbjct 434 HQLREQLVHIK 444 >sp|Q07497|EPHB5_CHICK Ephrin type-B receptor 5 OS=Gallus gallus OX=9031 GN=EPHB5 PE=2 SV=1 Length=1002 Score = 284 bits (727), Expect = 5e-79, Method: Composition-based stats. Identities = 81/331 (24%), Positives = 150/331 (45%), Gaps = 23/331 (7%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 P + I ++ + ++ ++K +G G FG Sbjct 590 RETPYTDRLQQYISTRGLGVKYYIDPSTYEDPNEAIREFAKEIDVSFIKIEEVIGSGEFG 649 Query 910 KVSLYCYDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968 +V + G E VA+K LK+ + R + E I+ H ++I +G Sbjct 650 EVCFGRLK--HPGKREYTVAIKTLKSGYTDEQRREFLSEASIMGQFEHPNVIHLEGVVTK 707 Query 969 QGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 + + +V E++ GSL +L + + QL+ + I GM YL +Y+HRDLAA Sbjct 708 S--RPVMIVTEFMENGSLDSFLRQKEGQFSVLQLVGMLRGIAAGMRYLSDMNYVHRDLAA 765 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPE--GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084 RN+L++++ + K+ DFGL++ + + + Y P+ W APE ++ KF +SDV Sbjct 766 RNILVNSNLVCKVSDFGLSRFLEDDASNPTYTGALGCKIPIRWTAPEAVQYRKFTSSSDV 825 Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144 WS+G+ ++E++++ + M+ + +++ RLP P CP + Sbjct 826 WSYGIVMWEVMSYGER--------------PYWDMSNQDVINAIDQDYRLPPPPDCPTVL 871 Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 + LM +CW+ + RP FE ++ L + K Sbjct 872 HLLMLDCWQKDRVQRPKFEQIVSALDKMIRK 902 Score = 270 bits (689), Expect = 5e-74, Method: Composition-based stats. Identities = 81/348 (23%), Positives = 134/348 (39%), Gaps = 42/348 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D I +G G V GRL+ G +E V + Sbjct 630 KEIDVSFIKIEEVIGSGEFGEVCFGRLKHPGK---------------------REYTVAI 668 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + D F AS+M Q H ++ + GV + ++VTE++E+G LD +LR Sbjct 669 KTLKSGYTDEQRREFLSEASIMGQFEHPNVIHLEGVVTKSRPVMIVTEFMENGSLDSFLR 728 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 ++ G + + + + +A+ + YL + N VH ++ RNIL+ ++ K+SD Sbjct 729 QKEGQFSVLQLVGMLRGIAAGMRYLSDMNYVHRDLAARNILVN-------SNLVCKVSDF 781 Query 761 GVGL---GALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ S I W APE + +++ D W +G + E+ G Sbjct 782 GLSRFLEDDASNPTYTGALGCKIPIRWTAPEAVQ--YRKFTSSSDVWSYGIVMWEVMSYG 839 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P S + + + +RLP P CP L L C + QRP F I+ L ++ Sbjct 840 ERPYWDMSNQDVINAIDQDYRLPPPPDCPTVLHLLMLDCWQKDRVQRPKFEQIVSALDKM 899 Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917 A T S S P + + + + Y Sbjct 900 IRKPSALKATGTGSSRPSQPLLSNSPPDFPSLSNAHEWLDAIKMGRYK 947 >sp|Q6VNS1|NTRK3_MOUSE NT-3 growth factor receptor OS=Mus musculus OX=10090 GN=Ntrk3 PE=1 SV=1 Length=825 Score = 281 bits (718), Expect = 6e-79, Method: Composition-based stats. Identities = 114/335 (34%), Positives = 160/335 (48%), Gaps = 36/335 (11%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914 P I + + N P + +R + R+LGEG FGKV L Sbjct 497 GPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAE 556 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 CY+ + +VAVKALK D R +++E ++L L HEHI+K+ G C D L Sbjct 557 CYNLSPTKDKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PL 613 Query 975 QLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQ 1017 +V EY+ G L +L H +GL+Q+L A QI GM YL +Q Sbjct 614 IMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQ 673 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 H++HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + K Sbjct 674 HFVHRDLATRNCLVGANLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRK 732 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFGV L+E+ T+ Q++ + E + +G L RP Sbjct 733 FTTESDVWSFGVILWEIFTYGKQ--------------PWFQLSNTEVIECITQGRVLERP 778 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 CP EVY +M CW+ E R + + IL + Sbjct 779 RVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813 Score = 263 bits (673), Expect = 5e-73, Method: Composition-based stats. Identities = 73/309 (24%), Positives = 126/309 (41%), Gaps = 51/309 (17%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + +++I LG+G V+ + + L P +D+ + V +K Sbjct 533 IKRRDIVLKRELGEGAFGKVF----------------LAECYNLSPTKDK---MLVAVKA 573 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702 L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR Sbjct 574 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633 Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 +G + ++ + +A Q+AS + YL +++ VH ++ RN L+ Sbjct 634 PDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV------ 687 Query 749 EGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 G + +K+ D G+ S + + I W+ PE + +T D W FG Sbjct 688 -GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGV 744 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860 L EI G+ P S +E + L P ++ + C EP QR + + Sbjct 745 ILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIK 804 Query 861 TILRDLTRL 869 I + L L Sbjct 805 EIYKILHAL 813 >sp|Q91044|NTRK3_CHICK NT-3 growth factor receptor OS=Gallus gallus OX=9031 GN=NTRK3 PE=1 SV=2 Length=827 Score = 281 bits (718), Expect = 6e-79, Method: Composition-based stats. Identities = 114/335 (34%), Positives = 160/335 (48%), Gaps = 36/335 (11%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914 P I + + N P + +R + R+LGEG FGKV L Sbjct 499 GPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAE 558 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 CY+ + +VAVKALK D R +++E ++L L HEHI+K+ G C D L Sbjct 559 CYNLSPTNDKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PL 615 Query 975 QLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQ 1017 +V EY+ G L +L H +GL+Q+L A QI GM YL +Q Sbjct 616 IMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQ 675 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 H++HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + K Sbjct 676 HFVHRDLATRNCLVGANLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRK 734 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFGV L+E+ T+ Q++ + E + +G L RP Sbjct 735 FTTESDVWSFGVILWEIFTYGKQ--------------PWFQLSNTEVIECITQGRVLERP 780 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 CP EVY +M CW+ E R + + IL + Sbjct 781 RVCPKEVYDIMLGCWQREPQQRLNIKEIYKILHAL 815 Score = 263 bits (672), Expect = 9e-73, Method: Composition-based stats. Identities = 73/309 (24%), Positives = 125/309 (40%), Gaps = 51/309 (17%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + +++I LG+G V+ + + L P D+ + V +K Sbjct 535 IKRRDIVLKRELGEGAFGKVF----------------LAECYNLSPTNDK---MLVAVKA 575 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702 L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR Sbjct 576 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 635 Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 +G + ++ + +A Q+AS + YL +++ VH ++ RN L+ Sbjct 636 PDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV------ 689 Query 749 EGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 G + +K+ D G+ S + + I W+ PE + +T D W FG Sbjct 690 -GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGV 746 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860 L EI G+ P S +E + L P ++ + C EP QR + + Sbjct 747 ILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDIMLGCWQREPQQRLNIK 806 Query 861 TILRDLTRL 869 I + L L Sbjct 807 EIYKILHAL 815 >sp|P29322|EPHA8_HUMAN Ephrin type-A receptor 8 OS=Homo sapiens OX=9606 GN=EPHA8 PE=1 SV=2 Length=1005 Score = 284 bits (726), Expect = 7e-79, Method: Composition-based stats. Identities = 90/321 (28%), Positives = 143/321 (45%), Gaps = 20/321 (6%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 Q + + S + + +G G G+V VA+ Sbjct 608 QFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRD-VPVAI 666 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 KALKA + R + E I+ H +II+ +G + +V EY+ GSL + Sbjct 667 KALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRG--RLAMIVTEYMENGSLDTF 724 Query 990 LPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 L H + QL+ + + GM YL Y+HRDLAARNVL+D++ + K+ DFGL++ Sbjct 725 LRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRV 784 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + + + G P+ W APE + F ASDVWSFGV ++E+L + + Sbjct 785 LEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGER------- 837 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 MT + +E G RLP P CP ++ LM +CW + + RP F ++ Sbjct 838 -------PYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVS 890 Query 1168 ILKTVHEKYQG-QAPSVFSVC 1187 +L + + +A + S C Sbjct 891 VLDALIRSPESLRATATVSRC 911 Score = 259 bits (662), Expect = 2e-70, Method: Composition-based stats. Identities = 78/325 (24%), Positives = 126/325 (39%), Gaps = 40/325 (12%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 ++ I +G G V GRLRV G +++ V Sbjct 627 TREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQ---------------------RDVPVA 665 Query 641 LKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +K L + + F AS+M Q H ++ + GV RG ++VTEY+E+G LD +L Sbjct 666 IKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFL 725 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R G + + + + + + + YL + VH ++ RN+L+ ++ K+SD Sbjct 726 RTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVD-------SNLVCKVSD 778 Query 760 PGVGL-------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 G+ A + I W APE + + S+A D W FG + E+ GE Sbjct 779 FGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIA--FRTFSSASDVWSFGVVMWEVLAYGE 836 Query 813 APLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P + + + + +RLP CP L L C + QRP F I+ L L Sbjct 837 RPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALI 896 Query 871 PHNLADVLTVNPDSPASDPTVFHKR 895 + T V Sbjct 897 RSPESLRATATVSRCPPPAFVRSCF 921 >sp|Q91987|NTRK2_CHICK BDNF/NT-3 growth factors receptor OS=Gallus gallus OX=9031 GN=NTRK2 PE=1 SV=1 Length=818 Score = 280 bits (716), Expect = 8e-79, Method: Composition-based stats. Identities = 109/334 (33%), Positives = 159/334 (48%), Gaps = 33/334 (10%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914 P I + + +T + P + + + R+LGEG FGKV L Sbjct 493 GPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAE 552 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 CY+ + +VAVK LK D R + +E ++L L HEHI+K+ G C + L Sbjct 553 CYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGD--PL 609 Query 975 QLVMEYVPLGSLRDYLPRHS--------------IGLAQLLLFAQQICEGMAYLHAQHYI 1020 +V EY+ G L +L H + +Q+L AQQI GM YL +QH++ Sbjct 610 IMVFEYMKHGDLNKFLRAHGPDAVLMAEGNRPAELTQSQMLHIAQQIAAGMVYLASQHFV 669 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + KF Sbjct 670 HRDLATRNCLVGENLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRKFTT 728 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS GV L+E+ T+ Q++ + E + +G L RP C Sbjct 729 ESDVWSLGVVLWEIFTYGKQ--------------PWYQLSNNEVIECITQGRVLQRPRTC 774 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 P EVY LM CW+ E R + + +L+ + + Sbjct 775 PKEVYDLMLGCWQREPHMRLNIKEIHSLLQNLAK 808 Score = 266 bits (681), Expect = 4e-74, Method: Composition-based stats. Identities = 72/306 (24%), Positives = 123/306 (40%), Gaps = 48/306 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + + I LG+G V+ + + L P +D+ + V +K Sbjct 529 IKRHNIVLKRELGEGAFGKVF----------------LAECYNLCPEQDK---ILVAVKT 569 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--- 700 L + + F+ A L++ + H H+ +GVCV G IMV EY++HG L+ +LR Sbjct 570 LKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 629 Query 701 ---------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 + + + +AQQ+A+ + YL +++ VH ++ RN L+ G Sbjct 630 PDAVLMAEGNRPAELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV-------GE 682 Query 752 SPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + +K+ D G+ S + + I W+ PE + +T D W G L Sbjct 683 NLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSLGVVLW 740 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 EI G+ P S +E + L P ++ L C EP R + + I Sbjct 741 EIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPKEVYDLMLGCWQREPHMRLNIKEIH 800 Query 864 RDLTRL 869 L L Sbjct 801 SLLQNL 806 >sp|Q5IFJ9|NTRK3_MACFA NT-3 growth factor receptor OS=Macaca fascicularis OX=9541 GN=NTRK3 PE=2 SV=1 Length=825 Score = 280 bits (717), Expect = 9e-79, Method: Composition-based stats. Identities = 114/335 (34%), Positives = 160/335 (48%), Gaps = 36/335 (11%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914 P I + + N P + +R + R+LGEG FGKV L Sbjct 497 GPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAE 556 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 CY+ + +VAVKALK D R +++E ++L L HEHI+K+ G C D L Sbjct 557 CYNLSPTKDKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PL 613 Query 975 QLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQ 1017 +V EY+ G L +L H +GL+Q+L A QI GM YL +Q Sbjct 614 IMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQ 673 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 H++HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + K Sbjct 674 HFVHRDLATRNCLVGANLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRK 732 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFGV L+E+ T+ Q++ + E + +G L RP Sbjct 733 FTTESDVWSFGVILWEIFTYGKQ--------------PWFQLSNTEVIECITQGRVLERP 778 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 CP EVY +M CW+ E R + + IL + Sbjct 779 RVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813 Score = 263 bits (672), Expect = 8e-73, Method: Composition-based stats. Identities = 73/309 (24%), Positives = 126/309 (41%), Gaps = 51/309 (17%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + +++I LG+G V+ + + L P +D+ + V +K Sbjct 533 IKRRDIVLKRELGEGAFGKVF----------------LAECYNLSPTKDK---MLVAVKA 573 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702 L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR Sbjct 574 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633 Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 +G + ++ + +A Q+AS + YL +++ VH ++ RN L+ Sbjct 634 PDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV------ 687 Query 749 EGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 G + +K+ D G+ S + + I W+ PE + +T D W FG Sbjct 688 -GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGV 744 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860 L EI G+ P S +E + L P ++ + C EP QR + + Sbjct 745 ILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIK 804 Query 861 TILRDLTRL 869 I + L L Sbjct 805 EIYKILHAL 813 >sp|Q5IS37|NTRK3_PANTR NT-3 growth factor receptor OS=Pan troglodytes OX=9598 GN=NTRK3 PE=2 SV=1 Length=825 Score = 280 bits (717), Expect = 9e-79, Method: Composition-based stats. Identities = 114/335 (34%), Positives = 160/335 (48%), Gaps = 36/335 (11%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914 P I + + N P + +R + R+LGEG FGKV L Sbjct 497 GPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAE 556 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 CY+ + +VAVKALK D R +++E ++L L HEHI+K+ G C D L Sbjct 557 CYNLSPTKDKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PL 613 Query 975 QLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQ 1017 +V EY+ G L +L H +GL+Q+L A QI GM YL +Q Sbjct 614 IMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQ 673 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 H++HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + K Sbjct 674 HFVHRDLATRNCLVGANLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRK 732 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFGV L+E+ T+ Q++ + E + +G L RP Sbjct 733 FTTESDVWSFGVILWEIFTYGKQ--------------PWFQLSNTEVIECITQGRVLERP 778 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 CP EVY +M CW+ E R + + IL + Sbjct 779 RVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813 Score = 263 bits (672), Expect = 8e-73, Method: Composition-based stats. Identities = 73/309 (24%), Positives = 126/309 (41%), Gaps = 51/309 (17%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + +++I LG+G V+ + + L P +D+ + V +K Sbjct 533 IKRRDIVLKRELGEGAFGKVF----------------LAECYNLSPTKDK---MLVAVKA 573 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702 L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR Sbjct 574 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633 Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 +G + ++ + +A Q+AS + YL +++ VH ++ RN L+ Sbjct 634 PDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV------ 687 Query 749 EGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 G + +K+ D G+ S + + I W+ PE + +T D W FG Sbjct 688 -GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGV 744 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860 L EI G+ P S +E + L P ++ + C EP QR + + Sbjct 745 ILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIK 804 Query 861 TILRDLTRL 869 I + L L Sbjct 805 EIYKILHAL 813 >sp|Q54H45|DRKB_DICDI Probable serine/threonine-protein kinase drkB OS=Dictyostelium discoideum OX=44689 GN=drkB PE=3 SV=1 Length=690 Score = 277 bits (708), Expect = 1e-78, Method: Composition-based stats. Identities = 79/286 (28%), Positives = 129/286 (45%), Gaps = 34/286 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHII 960 +G+G+FG+V L + G VAVK L A + + +EI++++ L H ++I Sbjct 396 RIGKGNFGEVYLGTWR------GSQVAVKKLPAHNINENILKEFHREINLMKNLRHPNVI 449 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI--GLAQLLLFAQQICEGMAYLHAQH 1018 ++ G C + + + EY+P GSL L I + + +G+ YLH Sbjct 450 QFLGSCLISPD--ICICTEYMPRGSLYSILHNEKIKISWSLVKRMMIDAAKGIIYLHGST 507 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL + N+L+D + VK+ DFGL+ +G W +PE L+ Sbjct 508 PVILHRDLKSHNLLVDENWKVKVADFGLSTIEQQG-----ATMTACGTPCWTSPEVLRSQ 562 Query 1077 KFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 ++ +DV+SFG+ L+E T D PP + + +G G R P Sbjct 563 RYTEKADVYSFGIILWECATRQDPYFGIPPFQVIFAVG---------------REGMRPP 607 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 P P + L+K+C S RPT E + IL+++ K P Sbjct 608 TPKYGPPKYIQLLKDCLNENPSQRPTMEQCLEILESIETKGFDDIP 653 Score = 236 bits (602), Expect = 2e-64, Method: Composition-based stats. Identities = 60/308 (19%), Positives = 108/308 (35%), Gaps = 45/308 (15%) Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 +R S R+ +D ++I +G+G VY G R Sbjct 366 IRKRLNSKRSGYTQIKDGKDIDTQQIKIGVRIGKGNFGEVYLGTWRGS------------ 413 Query 624 EDPLVPGRDRGQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 +V +K L + +I F+ +LM + H ++ G C+ P Sbjct 414 --------------QVAVKKLPAHNINENILKEFHREINLMKNLRHPNVIQFLGSCLISP 459 Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRN 739 + + TEY+ G L L E+ + + + A + YL ++H ++ N Sbjct 460 DICICTEYMPRGSLYSILHNEKIKISWSLVKRMMIDAAKGIIYLHGSTPVILHRDLKSHN 519 Query 740 ILLARLGLAEGTSPFIKLSDPGVGL--GALSREERVERIPWLAPECLPGGANSLSTAMDK 797 +L+ + +K++D G+ + W +PE L + + D Sbjct 520 LLVDE-------NWKVKVADFGLSTIEQQGATMTACGTPCWTSPEVLR--SQRYTEKADV 570 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---QHRLPEPSCPQLATLTSQCLTYEPT 854 + FG L E C + P P + R + P+ P+ L CL P+ Sbjct 571 YSFGIILWE-CATRQDPYFGIPPFQVIFAVGREGMRPPTPKYGPPKYIQLLKDCLNENPS 629 Query 855 QRPSFRTI 862 QRP+ Sbjct 630 QRPTMEQC 637 >sp|P54754|EPHB3_MOUSE Ephrin type-B receptor 3 OS=Mus musculus OX=10090 GN=Ephb3 PE=1 SV=2 Length=993 Score = 283 bits (724), Expect = 1e-78, Method: Composition-based stats. Identities = 84/355 (24%), Positives = 150/355 (42%), Gaps = 29/355 (8%) Query 844 LTSQCLTYE---PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 + CL + P + + ++ + ++ +K Sbjct 572 IALVCLRKQRHGPDAEYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIE 631 Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G FG+V VA+K LK + R + E I+ H +II Sbjct 632 EVIGAGEFGEVCRGRLKLPGRRE-VFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNII 690 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQH 1018 + +G + + ++ E++ +L +L + QL+ + I GM YL + Sbjct 691 RLEGVVTKS--RPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMN 748 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076 Y+HRDLAARN+L++++ + K+ DFGL++ + + Y G P+ W APE + Sbjct 749 YVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYR 808 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 KF ASDVWS+G+ ++E++++ + M+ + +E+ RLP Sbjct 809 KFTSASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVINAVEQDYRLPP 854 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE-----KYQGQAPSVFSV 1186 P CP ++ LM +CW + + RP F ++ L + K APS S Sbjct 855 PMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVTASAPSGMSQ 909 Score = 262 bits (669), Expect = 2e-71, Method: Composition-based stats. Identities = 81/363 (22%), Positives = 142/363 (39%), Gaps = 46/363 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G V GRL++ G +E+ V + Sbjct 621 KEIDVSCVKIEEVIGAGEFGEVCRGRLKLPGR---------------------REVFVAI 659 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + +++TE++E+ LD +LR Sbjct 660 KTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLR 719 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD Sbjct 720 LNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 772 Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ +IP W APE + ++A D W +G + E+ G Sbjct 773 GLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYG 830 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P S + + ++ +RLP P CP L L C + RP F I+ L +L Sbjct 831 ERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKL 890 Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG----E 925 + + +T + S S P + + + Y + G G + Sbjct 891 IRNAASLKVTASAPSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVGAGFASFD 950 Query 926 MVA 928 +VA Sbjct 951 LVA 953 >sp|Q86PM4|FGFR_HYDVU Fibroblast growth factor receptor OS=Hydra vulgaris OX=6087 GN=FGFR PE=2 SV=1 Length=816 Score = 280 bits (715), Expect = 1e-78, Method: Composition-based stats. Identities = 107/333 (32%), Positives = 159/333 (48%), Gaps = 31/333 (9%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 T + R L + + D +N L+ LGEG FG+V Sbjct 431 TSVSASYASRRFRHSLNNNLINDKQKLNLKIAPDPAWEIKLEQLETDCLLGEGAFGRVFR 490 Query 914 YCYDPTNDGTG-EMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGE 971 + TG + VAVK LK DC Q + EI++++++ H +I+ QG+ Sbjct 491 ATARDLPNHTGVQTVAVKMLKEDCCEQDLKDFISEIEVMKSIGKHINILNLLAVSSQQGK 550 Query 972 KSLQLVMEYVPLGSLRDYLPRH------------SIGLAQLLLFAQQICEGMAYLHAQHY 1019 L +V+EY G+LR +L + I L L F Q+ GM +L ++ Sbjct 551 --LYIVVEYCRHGNLRSFLKDNRPVMQANSVITKKITLYDLTSFCLQVARGMNFLASKKC 608 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+AARNVL+ L+KI DFGLA+ + E +YYR DG PV W A E L + + Sbjct 609 IHRDIAARNVLVGEGYLMKIADFGLARDIHE-QDYYRKCTDGRLPVKWMAIEALFDRVYT 667 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SD+WSFG+ +E++T G + + +L +LL++G R+ RP Sbjct 668 TQSDIWSFGILAWEIVTFG--------------GSPYPGIALEKLFDLLKQGYRMERPLN 713 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 C ++Y LM NCW+ S RPTF LI L+ + Sbjct 714 CTDDMYTLMLNCWKEIPSKRPTFSQLIEDLERM 746 Score = 220 bits (561), Expect = 2e-58, Method: Composition-based stats. Identities = 57/308 (19%), Positives = 113/308 (37%), Gaps = 48/308 (16%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + +++ LG+G V+ R + + V + Sbjct 467 WEIKLEQLETDCLLGEGAFGRVFRATARDLPNHTGVQ-------------------TVAV 507 Query 642 KVLDPSH-HDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 K+L F +M + H ++ + V + + +V EY HG L +L Sbjct 508 KMLKEDCCEQDLKDFISEIEVMKSIGKHINILNLLAVSSQQGKLYIVVEYCRHGNLRSFL 567 Query 700 RRER----------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 + R + + Q+A +++L +K +H ++ RN+L+ L Sbjct 568 KDNRPVMQANSVITKKITLYDLTSFCLQVARGMNFLASKKCIHRDIAARNVLVGEGYL-- 625 Query 750 GTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +K++D G+ ++ + + W+A E L +T D W FG Sbjct 626 -----MKIADFGLARDIHEQDYYRKCTDGRLPVKWMAIEALFDRV--YTTQSDIWSFGIL 678 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRT 861 EI G +P + + ++ +R+ P + TL C P++RP+F Sbjct 679 AWEIVTFGGSPYPGIALEKLFDLLKQGYRMERPLNCTDDMYTLMLNCWKEIPSKRPTFSQ 738 Query 862 ILRDLTRL 869 ++ DL R+ Sbjct 739 LIEDLERM 746 >sp|Q3UFB7|NTRK1_MOUSE High affinity nerve growth factor receptor OS=Mus musculus OX=10090 GN=Ntrk1 PE=1 SV=2 Length=799 Score = 278 bits (712), Expect = 2e-78, Method: Composition-based stats. Identities = 102/316 (32%), Positives = 157/316 (50%), Gaps = 35/316 (11%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKA 934 ++ + ++ + +LGEG FGKV L CY+ ND +VAVKALK Sbjct 492 HIMENPQYFSDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALK- 550 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993 + R +++E ++L L H+HI+++ G C + G L +V EY+ G L +L H Sbjct 551 EASENARQDFQREAELLTMLQHQHIVRFFGVCTEGG--PLLMVFEYMRHGDLNRFLRSHG 608 Query 994 ---------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 +GL QLL A Q+ GM YL + H++HRDLA RN L+ +VK Sbjct 609 PDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVK 668 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 IGDFG+++ + +YYRV P+ W PE + KF SDVWSFGV L+E+ T+ Sbjct 669 IGDFGMSRDIY-STDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYG 727 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 Q++ E + +G L RP CP +VY +M+ CW+ E Sbjct 728 KQ--------------PWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQ 773 Query 1159 RPTFENLIPILKTVHE 1174 R + +++ L+ + + Sbjct 774 RLSMKDVHARLQALAQ 789 Score = 265 bits (677), Expect = 1e-73, Method: Composition-based stats. Identities = 78/345 (23%), Positives = 129/345 (37%), Gaps = 52/345 (15%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 P E + +P+ S H + +++I LG+G V+ Sbjct 480 SPTEGKGSGLQGHIMENPQY--FSDTCVHHIKRQDIILKWELGEGAFGKVFLAEC----- 532 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 ++D+D ++ V +K L + + F A L++ + H H+ Sbjct 533 ----YNLLNDQD----------KMLVAVKALKEASENARQDFQREAELLTMLQHQHIVRF 578 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRE--------------RGHVPMAWKMVVAQQLA 719 GVC G +MV EY+ HG L+ +LR G + + + VA Q+A Sbjct 579 FGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVA 638 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE------RV 773 + + YL + + VH ++ RN L+ G +K+ D G+ S + + Sbjct 639 AGMVYLASLHFVHRDLATRNCLV-------GQGLVVKIGDFGMSRDIYSTDYYRVGGRTM 691 Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833 I W+ PE + ST D W FG L EI G+ P S +E + L Sbjct 692 LPIRWMPPESIL--YRKFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGREL 749 Query 834 --PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 P P + + C EP QR S + + L L + Sbjct 750 ERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQALAQAPPSY 794 >sp|Q90413|FGFR4_DANRE Fibroblast growth factor receptor 4 OS=Danio rerio OX=7955 GN=fgfr4 PE=1 SV=1 Length=922 Score = 281 bits (719), Expect = 2e-78, Method: Composition-based stats. Identities = 104/330 (32%), Positives = 158/330 (48%), Gaps = 42/330 (13%) Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE---MVA 928 + + + P F + L + LGEG FG+V N + VA Sbjct 553 CSPMLAGVMEFELPYDPDWEFPRENLTLGKPLGEGCFGQVVRAEAYGINKENQDHMATVA 612 Query 929 VKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 VK LK D + + E+++++ + H++II G C G L +++EY GSLR Sbjct 613 VKMLKDDATDKDLADLISEMELMKVMDKHKNIINLLGVCTQDG--PLYVLVEYASKGSLR 670 Query 988 DYL-----------------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030 +YL P + L+ A Q+ GM YL ++ IHRDLAARNVL Sbjct 671 EYLRARRPPGMDYTFDVTKVPEEQLTFKDLVSCAYQVARGMEYLASKRCIHRDLAARNVL 730 Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 + D ++KI DFGLA+ V + +YY+ +G PV W APE L + + + SDVWSFGV Sbjct 731 VTEDNVMKIADFGLARGVHQ-IDYYKKTTNGRMPVKWMAPEALFDRVYTHQSDVWSFGVL 789 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 ++E+ T L G + V L +LL+ G R+ +P C E+Y M+ Sbjct 790 MWEIFT--------------LGGSPYPGIPVEELFKLLKEGHRMDKPSNCTHELYMKMRE 835 Query 1151 CWETEASFRPTFENLIPILK----TVHEKY 1176 CW + RPTF+ L+ L ++ ++Y Sbjct 836 CWHAVPTQRPTFKQLVEELDRVLVSISDEY 865 Score = 232 bits (591), Expect = 1e-61, Method: Composition-based stats. Identities = 66/315 (21%), Positives = 113/315 (36%), Gaps = 51/315 (16%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L ++ +T LG+G V + E + + Sbjct 562 EFELPYDPDWEFPRENLTLGKPLGEGCFGQV-----------------VRAEAYGINKEN 604 Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVS-HTHLAFVHGVCVRGPENIMVTEYV 690 + V +K+L D L LM + H ++ + GVC + ++ EY Sbjct 605 QDHMATVAVKMLKDDATDKDLADLISEMELMKVMDKHKNIINLLGVCTQDGPLYVLVEYA 664 Query 691 EHGPLDVWLRRERG---------------HVPMAWKMVVAQQLASALSYLENKNLVHGNV 735 G L +LR R + + A Q+A + YL +K +H ++ Sbjct 665 SKGSLREYLRARRPPGMDYTFDVTKVPEEQLTFKDLVSCAYQVARGMEYLASKRCIHRDL 724 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLPGGAN 789 RN+L+ + +K++D G+ G ++ R+P W+APE L Sbjct 725 AARNVLVTEDNV-------MKIADFGLARGVHQIDYYKKTTNGRMPVKWMAPEALFDRV- 776 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847 + D W FG + EI G +P E + HR+ P +L + Sbjct 777 -YTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPSNCTHELYMKMRE 835 Query 848 CLTYEPTQRPSFRTI 862 C PTQRP+F+ + Sbjct 836 CWHAVPTQRPTFKQL 850 >sp|O42127|FGFR3_XENLA Fibroblast growth factor receptor 3 OS=Xenopus laevis OX=8355 GN=fgfr3 PE=2 SV=1 Length=802 Score = 278 bits (712), Expect = 2e-78, Method: Composition-based stats. Identities = 100/291 (34%), Positives = 145/291 (50%), Gaps = 38/291 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGWKQEIDILRTL-YHEH 958 LGEG FG+V + + VAVK LK D + S E+++++ + H++ Sbjct 468 LGEGCFGQVVMAEAIGIDKERPNKPATVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 527 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----------------IGLAQLL 1001 II G C G L +++EY GSLR+YL + L+ Sbjct 528 IINLLGACTQDG--PLYVLVEYASKGSLREYLKARRPPGMDYSFDACKIPAEQLTFKDLV 585 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 A Q+ GM YL +Q IHRDLAARNVL+ +D ++KI DFGLA+ + +YY+ +G Sbjct 586 SCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDI-HNIDYYKKTTNG 644 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 PV W APE L + + + SDVWS+GV L+E+ T L G + V Sbjct 645 RLPVKWMAPEALFDRIYTHHSDVWSYGVLLWEIFT--------------LGGSPYPGIPV 690 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 L +LL+ G R+ +P C E+Y +M+ CW S RP F+ L+ L V Sbjct 691 EELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPAFKQLVEDLDRV 741 Score = 232 bits (591), Expect = 2e-62, Method: Composition-based stats. Identities = 62/319 (19%), Positives = 114/319 (36%), Gaps = 51/319 (16%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 A+ L L + + +T LG+G V + E + Sbjct 442 ANVSELGLPLDPKWELLRSRLTLGKPLGEGCFGQV-----------------VMAEAIGI 484 Query 629 PGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMV 686 + V +K+L D L +M + H ++ + G C + ++ Sbjct 485 DKERPNKPATVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVL 544 Query 687 TEYVEHGPLDVWLRRERG---------------HVPMAWKMVVAQQLASALSYLENKNLV 731 EY G L +L+ R + + A Q+A + YL ++ + Sbjct 545 VEYASKGSLREYLKARRPPGMDYSFDACKIPAEQLTFKDLVSCAYQVARGMEYLASQKCI 604 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPECLP 785 H ++ RN+L+ + +K++D G+ ++ R+P W+APE L Sbjct 605 HRDLAARNVLVTDDNV-------MKIADFGLARDIHNIDYYKKTTNGRLPVKWMAPEALF 657 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLAT 843 + D W +G L EI G +P E + HR+ P +L Sbjct 658 DRI--YTHHSDVWSYGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYM 715 Query 844 LTSQCLTYEPTQRPSFRTI 862 + +C P+QRP+F+ + Sbjct 716 IMRECWHAVPSQRPAFKQL 734 >sp|P22455|FGFR4_HUMAN Fibroblast growth factor receptor 4 OS=Homo sapiens OX=9606 GN=FGFR4 PE=1 SV=2 Length=802 Score = 278 bits (712), Expect = 3e-78, Method: Composition-based stats. Identities = 103/304 (34%), Positives = 148/304 (49%), Gaps = 38/304 (13%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCY---DPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 F + L + LGEG FG+V DP VAVK LK + + + Sbjct 460 WEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVS 519 Query 947 EIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-------------- 991 E+++++ + H++II G C +G L +++E G+LR++L Sbjct 520 EMEVMKLIGRHKNIINLLGVCTQEG--PLYVIVECAAKGNLREFLRARRPPGPDLSPDGP 577 Query 992 ---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ V Sbjct 578 RSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGV 637 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 +YY+ +G PV W APE L + + + SDVWSFG+ L+E+ T Sbjct 638 HH-IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFT------------ 684 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 L G + V L LL G R+ RP CP E+Y LM+ CW S RPTF+ L+ Sbjct 685 --LGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEA 742 Query 1169 LKTV 1172 L V Sbjct 743 LDKV 746 Score = 237 bits (604), Expect = 5e-64, Method: Composition-based stats. Identities = 70/315 (22%), Positives = 119/315 (38%), Gaps = 51/315 (16%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 +L+L + + LG+G V +R E G + P R Sbjct 451 SLDLPLDPLWEFPRDRLVLGKPLGEGCFGQV----VRAEAFG------------MDPARP 494 Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690 Q V +K+L + D L +M + H ++ + GVC + ++ E Sbjct 495 -DQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECA 553 Query 691 EHGPLDVWLRRER---------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNV 735 G L +LR R G + + A Q+A + YLE++ +H ++ Sbjct 554 AKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDL 613 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGAN 789 RN+L+ + +K++D G+ G + + + W+APE L Sbjct 614 AARNVLVTEDNV-------MKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRV- 665 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847 + D W FG L EI G +P E + HR+ P P+L L + Sbjct 666 -YTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRE 724 Query 848 CLTYEPTQRPSFRTI 862 C P+QRP+F+ + Sbjct 725 CWHAAPSQRPTFKQL 739 >sp|Q06187|BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo sapiens OX=9606 GN=BTK PE=1 SV=3 Length=659 Score = 275 bits (702), Expect = 3e-78, Method: Composition-based stats. Identities = 87/426 (20%), Positives = 162/426 (38%), Gaps = 64/426 (15%) Query 446 SIRDGIHGPLLEPFVQAKLRPE--DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLR 503 + + + + L+ E +G +++ S S + ++V +S G +R Sbjct 277 EMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKS---TGDPQGVIR 332 Query 504 KFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLII 563 + + + F ++ EL Q + L+ + Sbjct 333 HYVVCSTPQSQYYLAEKHLFSTIPELINYHQHN---SAGLISRLKYP------------V 377 Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 + + +P T L S+ +D K++T L LG G V G+ R Sbjct 378 SQQNKNAPSTAGLGYGSW-EIDPKDLTFLKELGTGQFGVVKYGKWRG------------- 423 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 + V +K++ F E A +M +SH L ++GVC + Sbjct 424 ------------QYDVAIKMIKEGSMS-EDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPI 470 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 ++TEY+ +G L +LR R + + + + A+ YLE+K +H ++ RN L+ Sbjct 471 FIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVN 530 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKW 798 G+ +K+SD G+ L E + W PE L + S+ D W Sbjct 531 DQGV-------VKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLM--YSKFSSKSDIW 581 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 FG + EI G+ P + + SE + RL P + ++ T+ C + +R Sbjct 582 AFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADER 641 Query 857 PSFRTI 862 P+F+ + Sbjct 642 PTFKIL 647 Score = 256 bits (653), Expect = 1e-71, Method: Composition-based stats. Identities = 90/289 (31%), Positives = 142/289 (49%), Gaps = 28/289 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + L +++LG G FG V + D VA+K +K G + +E Sbjct 395 WEIDPKDLTFLKELGTGQFGVVKYGKWRGQYD-----VAIKMIKE--GSMSEDEFIEEAK 447 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQI 1007 ++ L HE +++ G C Q + + ++ EY+ G L +YL RH QLL + + Sbjct 448 VMMNLSHEKLVQLYGVCTKQ--RPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDV 505 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 CE M YL ++ ++HRDLAARN L+++ +VK+ DFGL++ V + Y PV W Sbjct 506 CEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDE--YTSSVGSKFPVRW 563 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 PE L KF SD+W+FGV ++E+ + L + + T E Sbjct 564 SPPEVLMYSKFSSKSDIWAFGVLMWEIYS--------------LGKMPYERFTNSETAEH 609 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP-ILKTVHEK 1175 + +G RL RP +VY +M +CW +A RPTF+ L+ IL + E+ Sbjct 610 IAQGLRLYRPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE 658 >sp|P00530|FPS_FUJSV Tyrosine-protein kinase transforming protein Fps OS=Fujinami sarcoma virus OX=11885 GN=V-FPS PE=3 SV=1 Length=873 Score = 280 bits (715), Expect = 3e-78, Method: Composition-based stats. Identities = 94/436 (22%), Positives = 168/436 (39%), Gaps = 80/436 (18%) Query 448 RDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPI 507 + HG + VQ +L G +L+ S +L+V DG R F I Sbjct 509 QAWYHGAIPRSEVQ-ELLKYSGDFLVRESQGKQ-EYVLSV-----LWDGQP----RHFII 557 Query 508 EQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGA 567 + D + LE G P++ L L +P + I++ A Sbjct 558 QAADNLYRLEDDG--LPTIPLLIDHLLQS----------------QRPITRKSGIVLTRA 599 Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 + ++ +++ +G+G V+ GRLR + Sbjct 600 VLKDK---------WVLNHEDVLLGERIGRGNFGEVFSGRLRADN--------------- 635 Query 628 VPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 V +K + ++ F + A ++ Q +H ++ + GVC + +V Sbjct 636 ---------TPVAVKSCRETLPPELKAKFLQEARILKQCNHPNIVRLIGVCTQKQPIYIV 686 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 E V+ G +LR + + M + + + A+ + YLE+K+ +H ++ RN L+ Sbjct 687 MELVQGGDFLSFLRSKGPRLKMKKLIKMMENAAAGMEYLESKHCIHRDLAARNCLVTEKN 746 Query 747 LAEGTSPFIKLSDPGVGL----GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGF 800 +K+SD G+ G + +++IP W APE L G S+ D W F Sbjct 747 -------TLKISDFGMSRQEEDGVYASTGGMKQIPVKWTAPEALNYG--WYSSESDVWSF 797 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPS 858 G L E G P + S + ++ RL PE + L +C Y+P +RPS Sbjct 798 GILLWEAFSLGAVPYANLSNQQTREAIEQGVRLEPPEQCPEDVYRLMQRCWEYDPHRRPS 857 Query 859 FRTILRDLTRLQPHNL 874 F + +DL ++ + Sbjct 858 FGAVHQDLIAIRKRHR 873 Score = 273 bits (698), Expect = 7e-76, Method: Composition-based stats. Identities = 85/290 (29%), Positives = 140/290 (48%), Gaps = 23/290 (8%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 V + + +G G+FG+V N VAVK+ + P+ ++ + QE Sbjct 605 WVLNHEDVLLGERIGRGNFGEVFSGRLRADN----TPVAVKSCRETLPPELKAKFLQEAR 660 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQI 1007 IL+ H +I++ G C + + + +VME V G +L + + +L+ + Sbjct 661 ILKQCNHPNIVRLIGVCTQK--QPIYIVMELVQGGDFLSFLRSKGPRLKMKKLIKMMENA 718 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 GM YL ++H IHRDLAARN L+ +KI DFG+++ +G Y PV W Sbjct 719 AAGMEYLESKHCIHRDLAARNCLVTEKNTLKISDFGMSRQEEDGV-YASTGGMKQIPVKW 777 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE L + SDVWSFG+ L+E + L + ++ + E Sbjct 778 TAPEALNYGWYSSESDVWSFGILLWEAFS--------------LGAVPYANLSNQQTREA 823 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 +E+G RL P++CP +VY LM+ CWE + RP+F + L + ++++ Sbjct 824 IEQGVRLEPPEQCPEDVYRLMQRCWEYDPHRRPSFGAVHQDLIAIRKRHR 873 >sp|P24786|NTRK3_PIG NT-3 growth factor receptor OS=Sus scrofa OX=9823 GN=NTRK3 PE=2 SV=1 Length=825 Score = 278 bits (712), Expect = 4e-78, Method: Composition-based stats. Identities = 114/332 (34%), Positives = 160/332 (48%), Gaps = 36/332 (11%) Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY-CYD 917 I + + N P + +R + R+LGEG FGKV L CY+ Sbjct 500 HSVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYN 559 Query 918 PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLV 977 + +VAVKALK D R +++E ++L L HEHI+K+ G C D L +V Sbjct 560 LSPTKVKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PLIMV 616 Query 978 MEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQHYI 1020 EY+ G L +L H +GL+Q+L A QIC GM YL +QH++ Sbjct 617 FEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQICSGMVYLASQHFV 676 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + KF Sbjct 677 HRDLATRNCLVGANLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRKFTT 735 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWSFGV L+E+ T+ Q++ + E + +G L RP C Sbjct 736 ESDVWSFGVILWEIFTYGKQ--------------PWFQLSNTEVIECITQGRVLERPRVC 781 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P EVY +M CW+ E R + + IL + Sbjct 782 PKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813 Score = 258 bits (660), Expect = 3e-71, Method: Composition-based stats. Identities = 69/309 (22%), Positives = 119/309 (39%), Gaps = 51/309 (17%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + +++I LG+G V+ ++ V +K Sbjct 533 IKRRDIVLKRELGEGAFGKVFLAECYNLSPTKV-------------------KMLVAVKA 573 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702 L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR Sbjct 574 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633 Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 +G + ++ + +A Q+ S + YL +++ VH ++ RN L+ Sbjct 634 PDAMILVDGQPRQAKGELGLSQMLHIASQICSGMVYLASQHFVHRDLATRNCLV------ 687 Query 749 EGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 G + +K+ D G+ S + + I W+ PE + +T D W FG Sbjct 688 -GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGV 744 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860 L EI G+ P S +E + L P ++ + C EP QR + + Sbjct 745 ILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIK 804 Query 861 TILRDLTRL 869 I + L L Sbjct 805 EIYKILHAL 813 >sp|P35739|NTRK1_RAT High affinity nerve growth factor receptor OS=Rattus norvegicus OX=10116 GN=Ntrk1 PE=1 SV=1 Length=799 Score = 278 bits (710), Expect = 4e-78, Method: Composition-based stats. Identities = 102/316 (32%), Positives = 156/316 (49%), Gaps = 35/316 (11%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKA 934 ++ + ++ + +LGEG FGKV L CY+ ND +VAVKALK Sbjct 492 HIMENPQYFSDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALK- 550 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993 + R + +E ++L L H+HI+++ G C + G L +V EY+ G L +L H Sbjct 551 ETSENARQDFHREAELLTMLQHQHIVRFFGVCTEGG--PLLMVFEYMRHGDLNRFLRSHG 608 Query 994 ---------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 +GL QLL A Q+ GM YL + H++HRDLA RN L+ +VK Sbjct 609 PDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVK 668 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 IGDFG+++ + +YYRV P+ W PE + KF SDVWSFGV L+E+ T+ Sbjct 669 IGDFGMSRDIY-STDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYG 727 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 Q++ E + +G L RP CP +VY +M+ CW+ E Sbjct 728 KQ--------------PWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQ 773 Query 1159 RPTFENLIPILKTVHE 1174 R + +++ L+ + + Sbjct 774 RLSMKDVHARLQALAQ 789 Score = 265 bits (678), Expect = 9e-74, Method: Composition-based stats. Identities = 78/345 (23%), Positives = 130/345 (38%), Gaps = 52/345 (15%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 P E + +P+ S H + +++I LG+G V+ Sbjct 480 SPTEGKGSGLQGHIMENPQY--FSDTCVHHIKRQDIILKWELGEGAFGKVFLAEC----- 532 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 ++D+D ++ V +K L + + F+ A L++ + H H+ Sbjct 533 ----YNLLNDQD----------KMLVAVKALKETSENARQDFHREAELLTMLQHQHIVRF 578 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRE--------------RGHVPMAWKMVVAQQLA 719 GVC G +MV EY+ HG L+ +LR G + + + VA Q+A Sbjct 579 FGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVA 638 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE------RV 773 + + YL + + VH ++ RN L+ G +K+ D G+ S + + Sbjct 639 AGMVYLASLHFVHRDLATRNCLV-------GQGLVVKIGDFGMSRDIYSTDYYRVGGRTM 691 Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833 I W+ PE + ST D W FG L EI G+ P S +E + L Sbjct 692 LPIRWMPPESIL--YRKFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGREL 749 Query 834 --PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 P P + + C EP QR S + + L L + Sbjct 750 ERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQALAQAPPSY 794 >sp|O22558|STY8_ARATH Serine/threonine-protein kinase STY8 OS=Arabidopsis thaliana OX=3702 GN=STY8 PE=1 SV=2 Length=546 Score = 271 bits (692), Expect = 4e-78, Method: Composition-based stats. Identities = 83/302 (27%), Positives = 143/302 (47%), Gaps = 29/302 (10%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CG 937 + + +D LK + + G +G + Y + VA+K LK D Sbjct 268 CIEIPTDGTDEWEIDVTQLKIEKKVASGSYGDLHRGTY------CSQEVAIKFLKPDRVN 321 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995 + + QE+ I+R + H++++++ G C +L +V E++ GS+ D+L + Sbjct 322 NEMLREFSQEVFIMRKVRHKNVVQFLGACTRS--PTLCIVTEFMARGSIYDFLHKQKCAF 379 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 L LL A + +GM+YLH + IHRDL N+L+D LVK+ DFG+A+ E Sbjct 380 KLQTLLKVALDVAKGMSYLHQNNIIHRDLKTANLLMDEHGLVKVADFGVARVQIESG--- 436 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 V W APE ++ + + +DV+S+ + L+ELLT P FL + A Sbjct 437 -VMTAETGTYRWMAPEVIEHKPYNHKADVFSYAIVLWELLTG-----DIPYAFLTPLQAA 490 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 G ++++G R P K +V L++ CW + RP FE +I +L+ + ++ Sbjct 491 VG---------VVQKGLRPKIPKKTHPKVKGLLERCWHQDPEQRPLFEEIIEMLQQIMKE 541 Query 1176 YQ 1177 Sbjct 542 VN 543 Score = 236 bits (602), Expect = 8e-66, Method: Composition-based stats. Identities = 57/271 (21%), Positives = 114/271 (42%), Gaps = 18/271 (7%) Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQV 665 ++ + E K+ R V +K L P ++++ F + +M +V Sbjct 279 WEIDVTQLKIEKKVASGSYGDLHRGTYCSQEVAIKFLKPDRVNNEMLREFSQEVFIMRKV 338 Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL 725 H ++ G C R P +VTE++ G + +L +++ + + VA +A +SYL Sbjct 339 RHKNVVQFLGACTRSPTLCIVTEFMARGSIYDFLHKQKCAFKLQTLLKVALDVAKGMSYL 398 Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR---EERVERIPWLAPE 782 N++H ++ N+L+ GL +K++D GV + W+APE Sbjct 399 HQNNIIHRDLKTANLLMDEHGL-------VKVADFGVARVQIESGVMTAETGTYRWMAPE 451 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCP 839 + + D + + L E+ G+ P +P + + ++P+ + P Sbjct 452 VIEH--KPYNHKADVFSYAIVLWELL-TGDIPYAFLTPLQAAVGVVQKGLRPKIPKKTHP 508 Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 ++ L +C +P QRP F I+ L ++ Sbjct 509 KVKGLLERCWHQDPEQRPLFEEIIEMLQQIM 539 >sp|F4JTP5|STY46_ARATH Serine/threonine-protein kinase STY46 OS=Arabidopsis thaliana OX=3702 GN=STY46 PE=1 SV=1 Length=575 Score = 272 bits (695), Expect = 4e-78, Method: Composition-based stats. Identities = 78/297 (26%), Positives = 139/297 (47%), Gaps = 29/297 (10%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CG 937 V + +D + ++LK + G +G + Y + VA+K LK + Sbjct 272 HVPIPNDGTDVWEINLKHLKFGHKIASGSYGDLYKGTY------CSQEVAIKVLKPERLD 325 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995 + QE+ I+R + H++++++ G C L +V E++P GS+ DYL + Sbjct 326 SDLEKEFAQEVFIMRKVRHKNVVQFIGACTKP--PHLCIVTEFMPGGSVYDYLHKQKGVF 383 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 L L A IC+GM+YLH + IHRDL A N+L+D + +VK+ DFG+A+ Sbjct 384 KLPTLFKVAIDICKGMSYLHQNNIIHRDLKAANLLMDENEVVKVADFGVARV----KAQT 439 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 V W APE ++ + + +DV+S+G+ L+ELLT + Sbjct 440 GVMTAETGTYRWMAPEVIEHKPYDHKADVFSYGIVLWELLTGKLPYEY------------ 487 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + ++++G R P ++ L++ WE +++ RP F +I L+ + Sbjct 488 --MTPLQAAVGVVQKGLRPTIPKNTHPKLAELLERLWEHDSTQRPDFSEIIEQLQEI 542 Score = 245 bits (626), Expect = 9e-69, Method: Composition-based stats. Identities = 61/298 (20%), Positives = 118/298 (40%), Gaps = 44/298 (15%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 ++ K + + G+ ++Y+G + V Sbjct 281 DVWEINLKHLKFGHKIASGSYGDLYKGTYCSQ--------------------------EV 314 Query 640 VLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +KVL P D+ F + +M +V H ++ G C + P +VTE++ G + Sbjct 315 AIKVLKPERLDSDLEKEFAQEVFIMRKVRHKNVVQFIGACTKPPHLCIVTEFMPGGSVYD 374 Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 +L +++G + VA + +SYL N++H ++ N+L+ + +K+ Sbjct 375 YLHKQKGVFKLPTLFKVAIDICKGMSYLHQNNIIHRDLKAANLLMDE-------NEVVKV 427 Query 758 SDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 +D GV W+APE + D + +G L E+ G+ P Sbjct 428 ADFGVARVKAQTGVMTAETGTYRWMAPEVIEH--KPYDHKADVFSYGIVLWELL-TGKLP 484 Query 815 LQSRSPSEKE-HFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + +P + Q+ R +P+ + P+LA L + ++ TQRP F I+ L + Sbjct 485 YEYMTPLQAAVGVVQKGLRPTIPKNTHPKLAELLERLWEHDSTQRPDFSEIIEQLQEI 542 >sp|P35991|BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus musculus OX=10090 GN=Btk PE=1 SV=4 Length=659 Score = 274 bits (700), Expect = 6e-78, Method: Composition-based stats. Identities = 88/426 (21%), Positives = 162/426 (38%), Gaps = 64/426 (15%) Query 446 SIRDGIHGPLLEPFVQAKLRPE--DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLR 503 + + + + L+ E +G +++ S S + ++V +S G +R Sbjct 277 EMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKS---TGEPQGVIR 332 Query 504 KFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLII 563 + + + F ++ EL Q + L+ + Sbjct 333 HYVVCSTPQSQYYLAEKHLFSTIPELINYHQHN---SAGLISRLKYP------------V 377 Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 + + +P T L S+ +D K++T L LG G V G+ R Sbjct 378 SKQNKNAPSTAGLGYGSW-EIDPKDLTFLKELGTGQFGVVKYGKWRG------------- 423 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 + V +K++ F E A +M +SH L ++GVC + Sbjct 424 ------------QYDVAIKMIREGSMS-EDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPI 470 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 ++TEY+ +G L +LR R + + + + A+ YLE+K +H ++ RN L+ Sbjct 471 FIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVN 530 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVE-----RIPWLAPECLPGGANSLSTAMDKW 798 G+ +K+SD G+ L E + W PE L + S+ D W Sbjct 531 DQGV-------VKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLM--YSKFSSKSDIW 581 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 FG + EI G+ P + + SE + RL P + ++ T+ C + +R Sbjct 582 AFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASERVYTIMYSCWHEKADER 641 Query 857 PSFRTI 862 PSF+ + Sbjct 642 PSFKIL 647 Score = 254 bits (648), Expect = 5e-71, Method: Composition-based stats. Identities = 88/289 (30%), Positives = 141/289 (49%), Gaps = 28/289 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + L +++LG G FG V + D VA+K ++ G + +E Sbjct 395 WEIDPKDLTFLKELGTGQFGVVKYGKWRGQYD-----VAIKMIRE--GSMSEDEFIEEAK 447 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQI 1007 ++ L HE +++ G C Q + + ++ EY+ G L +YL RH QLL + + Sbjct 448 VMMNLSHEKLVQLYGVCTKQ--RPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDV 505 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 CE M YL ++ ++HRDLAARN L+++ +VK+ DFGL++ V + Y PV W Sbjct 506 CEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDE--YTSSVGSKFPVRW 563 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 PE L KF SD+W+FGV ++E+ + L + + T E Sbjct 564 SPPEVLMYSKFSSKSDIWAFGVLMWEIYS--------------LGKMPYERFTNSETAEH 609 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP-ILKTVHEK 1175 + +G RL RP VY +M +CW +A RP+F+ L+ IL + E+ Sbjct 610 IAQGLRLYRPHLASERVYTIMYSCWHEKADERPSFKILLSNILDVMDEE 658 >sp|O48814|BIK1_ARATH Serine/threonine-protein kinase BIK1 OS=Arabidopsis thaliana OX=3702 GN=BIK1 PE=1 SV=1 Length=395 Score = 265 bits (677), Expect = 7e-78, Method: Composition-based stats. Identities = 84/288 (29%), Positives = 132/288 (46%), Gaps = 18/288 (6%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +GEG FG V D PT GTG ++AVK L + HR W EI+ L L H Sbjct 73 IGEGGFGCVFKGWLDESTLTPTKPGTGLVIAVKKLNQEGFQGHRE-WLTEINYLGQLSHP 131 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMA 1012 +++K G C + + LV E++ GSL ++L R + + A +G+A Sbjct 132 NLVKLIGYCLEDEHR--LLVYEFMQKGSLENHLFRRGAYFKPLPWFLRVNVALDAAKGLA 189 Query 1013 YLHAQ--HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 +LH+ I+RD+ A N+LLD D K+ DFGLA+ P G Y V + AP Sbjct 190 FLHSDPVKVIYRDIKASNILLDADYNAKLSDFGLARDGPMGDLSY-VSTRVMGTYGYAAP 248 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTELL 1128 E + SDV+SFGV L E+L+ + + P K L+ A+ +T R + ++ Sbjct 249 EYMSSGHLNARSDVYSFGVLLLEILSGKRALDHNRPAKEENLVDWARPYLTSKRKVLLIV 308 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 + + + + C E RPT + ++ L+ + + Sbjct 309 DNRLDTQYLPEEAVRMASVAVQCLSFEPKSRPTMDQVVRALQQLQDNL 356 Score = 245 bits (625), Expect = 1e-70, Method: Composition-based stats. Identities = 77/376 (20%), Positives = 139/376 (37%), Gaps = 54/376 (14%) Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 G S + + ++ + S +G+G V++G L D Sbjct 42 TEGEILSSTPVKSFTFNELKLATRNFRPDSVIGEGGFGCVFKGWL--------------D 87 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 E L P + G L + +K L+ + + + Q+SH +L + G C+ Sbjct 88 ESTLTPTKP-GTGLVIAVKKLNQEGFQGHREWLTEINYLGQLSHPNLVKLIGYCLEDEHR 146 Query 684 IMVTEYVEHGPLDVWLRRER---GHVPMAWKMVVAQQLASALSYLENK--NLVHGNVCGR 738 ++V E+++ G L+ L R +P ++ VA A L++L + +++ ++ Sbjct 147 LLVYEFMQKGSLENHLFRRGAYFKPLPWFLRVNVALDAAKGLAFLHSDPVKVIYRDIKAS 206 Query 739 NILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPECLPGGANSLS 792 NILL KLSD G+ + + + APE + G L+ Sbjct 207 NILLD-------ADYNAKLSDFGLARDGPMGDLSYVSTRVMGTYGYAAPEYMSSG--HLN 257 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ--------------HRLPEPSC 838 D + FG LLEI A +R E+ + +RL Sbjct 258 ARSDVYSFGVLLLEILSGKRALDHNRPAKEENLVDWARPYLTSKRKVLLIVDNRLDTQYL 317 Query 839 P----QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894 P ++A++ QCL++EP RP+ ++R L +LQ + T Sbjct 318 PEEAVRMASVAVQCLSFEPKSRPTMDQVVRALQQLQDNLGKPSQTNPVKDTKKLGFKTGT 377 Query 895 RYLKKIRDLGEGHFGK 910 + R + FG+ Sbjct 378 TKSSEKRFTQK-PFGR 392 >sp|P54758|EPHA6_RAT Ephrin type-A receptor 6 OS=Rattus norvegicus OX=10116 GN=Epha6 PE=2 SV=2 Length=1035 Score = 281 bits (720), Expect = 7e-78, Method: Composition-based stats. Identities = 87/363 (24%), Positives = 152/363 (42%), Gaps = 57/363 (16%) Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911 E +R + ++ + D + ++ R +G G FG+V Sbjct 585 EEKRRTHLQNSHLRFPGIKTYIDPDTYEDPSLAVHEFEKEIDPSRIRIERVIGAGEFGEV 644 Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 T VA+K LK + R + +E I+ H +II+ +G + Sbjct 645 CSGRLK-TPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSF 703 Query 972 ----------------------------------------KSLQLVMEYVPLGSLRDYLP 991 + + +V+EY+ GSL +L Sbjct 704 PAIGVEAFCPSFLRAGFLNGIQAPHPVTAGGSLPPRIPAGRPVMIVVEYMENGSLDSFLR 763 Query 992 RHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL++ + Sbjct 764 KHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLE 823 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 + E G P+ W APE + KF ASDVWS+G+ ++E++++ + Sbjct 824 DDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDVWSYGIVMWEVMSYGER--------- 874 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 +M+ + +E G RLP P CP ++ LM +CW+ E + RP F +++ L Sbjct 875 -----PYWEMSNQDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFL 929 Query 1170 KTV 1172 + Sbjct 930 DKL 932 Score = 263 bits (673), Expect = 9e-72, Method: Composition-based stats. Identities = 87/404 (22%), Positives = 135/404 (33%), Gaps = 88/404 (22%) Query 570 SPRTLNLSQLSFHR----VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 P T L+ H +D I +G G V GRL+ G Sbjct 607 DPDTYEDPSLAVHEFEKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGK------------ 654 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVR----- 679 +E+ V +K L H D F AS+M Q H ++ + GV + Sbjct 655 ---------REIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPA 705 Query 680 -------------------------------------GPENIMVTEYVEHGPLDVWLRRE 702 G ++V EY+E+G LD +LR+ Sbjct 706 IGVEAFCPSFLRAGFLNGIQAPHPVTAGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKH 765 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 GH + + + + +AS + YL + VH ++ RNIL+ ++ K+SD G+ Sbjct 766 DGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVN-------SNLVCKVSDFGL 818 Query 763 GL-------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 A + I W APE + S+A D W +G + E+ GE P Sbjct 819 SRVLEDDPEAAYTTTGGKIPIRWTAPEAIA--YRKFSSASDVWSYGIVMWEVMSYGERPY 876 Query 816 QSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 S + + +RL P P L L C E RP F I+ L +L + Sbjct 877 WEMSNQDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNP 936 Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917 A V + Y + + + Y Sbjct 937 SALHTLVEDILVMPESPGDVPEYPLFVTVGDW--LDSIKMGQYK 978 >sp|Q9LTC0|PBL19_ARATH Probable serine/threonine-protein kinase PBL19 OS=Arabidopsis thaliana OX=3702 GN=PBL19 PE=1 SV=1 Length=410 Score = 265 bits (678), Expect = 1e-77, Method: Composition-based stats. Identities = 82/286 (29%), Positives = 128/286 (45%), Gaps = 11/286 (4%) Query 903 LGEGHFGKVSLYCYDPTNDGTG--EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +GEG FG V D + +VA+K L G Q W E+ L + H +++ Sbjct 92 IGEGGFGIVYKGKILSNGDSSDPPLVVAIKKLNR-QGLQGHKQWLAEVQFLGVVNHPNVV 150 Query 961 KYKGCCEDQGEKSL--QLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH 1015 K G C + GE + LV EY+ SL D+L H++ + L EG+ YLH Sbjct 151 KLIGYCSEDGETGIERLLVYEYMSNRSLEDHLFPRRSHTLPWKKRLEIMLGAAEGLTYLH 210 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 I+RD + NVLLD+ K+ DFGLA+ P+G + V + APE ++ Sbjct 211 DLKVIYRDFKSSNVLLDDQFCPKLSDFGLAREGPDGDNTH-VTTARVGTHGYAAPEYVQT 269 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQ--SPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 SDV+SFGV LYE++T + + P + L + + R + +++ R Sbjct 270 GHLRLKSDVYSFGVVLYEIITGRRTIERNKPVAERRLLDWVKEYPADSQRFSMIVDPRLR 329 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 P + L C + RPT E ++ LK + E+ + Sbjct 330 NNYPAAGARSLAKLADLCLKKNDKERPTMEIVVERLKKIIEESDSE 375 Score = 225 bits (573), Expect = 2e-63, Method: Composition-based stats. Identities = 75/410 (18%), Positives = 137/410 (33%), Gaps = 66/410 (16%) Query 529 LGAALQGCLLRAGDDCFSLRRC-CLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587 L + R+ F+L+ LP P +L R NL S+ + + Sbjct 30 LQNSAPELTNRSETSSFNLQTPRSLPSPRSIKDLYTEREQ-------NLRVFSYEELSKA 82 Query 588 EITQLSHL--GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 L G+G VY+G++ G L V +K L+ Sbjct 83 TYVFSRKLVIGEGGFGIVYKGKILSNGDSSDPP------------------LVVAIKKLN 124 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP----ENIMVTEYVEHGPLDVWLRR 701 + + V+H ++ + G C E ++V EY+ + L+ L Sbjct 125 RQGLQGHKQWLAEVQFLGVVNHPNVVKLIGYCSEDGETGIERLLVYEYMSNRSLEDHLFP 184 Query 702 ERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 R H +P ++ + A L+YL + +++ + N+LL KLSD Sbjct 185 RRSHTLPWKKRLEIMLGAAEGLTYLHDLKVIYRDFKSSNVLLDDQFCP-------KLSDF 237 Query 761 GVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ + RV + APE + G L D + FG L EI Sbjct 238 GLAREGPDGDNTHVTTARVGTHGYAAPEYVQTGHLRL--KSDVYSFGVVLYEIITGRRTI 295 Query 815 LQSRSPSE------KEHFYQRQHRLPEPSCPQ------------LATLTSQCLTYEPTQR 856 +++ +E + + R P+ LA L CL +R Sbjct 296 ERNKPVAERRLLDWVKEYPADSQRFSMIVDPRLRNNYPAAGARSLAKLADLCLKKNDKER 355 Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906 P+ ++ L ++ + ++ + + V ++ K + G Sbjct 356 PTMEIVVERLKKIIEESDSEDYPMATTTTKESSQVRRRQVAKPEKQSLRG 405 >sp|Q07407|FGFR1_DROME Fibroblast growth factor receptor homolog 1 OS=Drosophila melanogaster OX=7227 GN=htl PE=1 SV=3 Length=729 Score = 275 bits (702), Expect = 1e-77, Method: Composition-based stats. Identities = 100/347 (29%), Positives = 160/347 (46%), Gaps = 44/347 (13%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 T I + T + + + P + +L LGEG FG+V + Sbjct 373 TMIMPVVRIQKQRTTVLQNGNEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVM 432 Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEK 972 + +VAVK +K + +E+++++ + H +II GCC G Sbjct 433 A------EVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINIINLLGCCSQNG-- 484 Query 973 SLQLVMEYVPLGSLRDYLPR---------------------HSIGLAQLLLFAQQICEGM 1011 L +++EY P G+L+D+L + H I L+ FA QI GM Sbjct 485 PLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGM 544 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 YL ++ IHRDLAARNVL+ +D ++KI DFGLA+ + + +YYR +G P+ W APE Sbjct 545 DYLASRRCIHRDLAARNVLVSDDYVLKIADFGLARDI-QSTDYYRKNTNGRLPIKWMAPE 603 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 L+E + SDVWS+G+ L+E++T+ M+ L L G Sbjct 604 SLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTI-------------MSAEELYTYLMSG 650 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 +R+ +P KC +Y LM+ CW A RP F ++ + + + + Sbjct 651 QRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTKED 697 Score = 231 bits (590), Expect = 9e-63, Method: Composition-based stats. Identities = 63/354 (18%), Positives = 117/354 (33%), Gaps = 66/354 (19%) Query 554 QPGETSNLIIMRGARASPR-TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 + + ++ G +P S + + + + LG+G V Sbjct 380 RIQKQRTTVLQNGNEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRV--------- 430 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQV-SHTHL 670 V +K++ H D +A +M + H ++ Sbjct 431 -----------------VMAEVNNAIVAVKMVKEGHTDDDIASLVREMEVMKIIGRHINI 473 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-------------------VPMAWK 711 + G C + ++ EY HG L +L + R + Sbjct 474 INLLGCCSQNGPLYVIVEYAPHGNLKDFLYKNRPFGRDQDRDSSQPPPSPPAHVITEKDL 533 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----L 767 + A Q+A + YL ++ +H ++ RN+L++ +K++D G+ Sbjct 534 IKFAHQIARGMDYLASRRCIHRDLAARNVLVS-------DDYVLKIADFGLARDIQSTDY 586 Query 768 SREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS-RSPSEKE 824 R+ R+P W+APE L + D W +G L EI G+ P + S E Sbjct 587 YRKNTNGRLPIKWMAPESLQEKF--YDSKSDVWSYGILLWEIMTYGQQPYPTIMSAEELY 644 Query 825 HFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 + R+ P + L QC + RP F I+ + +L Sbjct 645 TYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTKEDY 698 >sp|Q5IS82|NTRK3_SAIBB NT-3 growth factor receptor OS=Saimiri boliviensis boliviensis OX=39432 GN=NTRK3 PE=2 SV=1 Length=825 Score = 276 bits (707), Expect = 2e-77, Method: Composition-based stats. Identities = 113/335 (34%), Positives = 159/335 (47%), Gaps = 36/335 (11%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914 P I + + N P + +R + R+LGEG FGKV L Sbjct 497 GPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAE 556 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 CY+ + +VAVKALK D R +++E ++L L HEHI+K+ G C D L Sbjct 557 CYNLSPTKDKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PL 613 Query 975 QLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQ 1017 +V EY+ G L +L H +GL+Q+L A QI GM YL +Q Sbjct 614 IMVFEYMKHGDLNKFLRAHGPDAMILVDGQPXQAKGELGLSQMLHIASQIASGMVYLASQ 673 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 H++HRDLA RN + + LVKIGDFG+++ V +YYRV P+ W PE + K Sbjct 674 HFVHRDLATRNCXVGANLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRK 732 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWSFGV L+E+ T+ Q++ + E + +G L RP Sbjct 733 FTTESDVWSFGVILWEIFTYGKQ--------------PWFQLSNTEVIECITQGRVLERP 778 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 CP EVY +M CW+ E R + + IL + Sbjct 779 RVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 813 Score = 259 bits (661), Expect = 2e-71, Method: Composition-based stats. Identities = 72/309 (23%), Positives = 125/309 (40%), Gaps = 51/309 (17%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + +++I LG+G V+ + + L P +D+ + V +K Sbjct 533 IKRRDIVLKRELGEGAFGKVF----------------LAECYNLSPTKDK---MLVAVKA 573 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702 L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR Sbjct 574 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633 Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 +G + ++ + +A Q+AS + YL +++ VH ++ RN + Sbjct 634 PDAMILVDGQPXQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCXV------ 687 Query 749 EGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 G + +K+ D G+ S + + I W+ PE + +T D W FG Sbjct 688 -GANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGV 744 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860 L EI G+ P S +E + L P ++ + C EP QR + + Sbjct 745 ILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIK 804 Query 861 TILRDLTRL 869 I + L L Sbjct 805 EIYKILHAL 813 >sp|Q2MHE4|HT1_ARATH Serine/threonine/tyrosine-protein kinase HT1 OS=Arabidopsis thaliana OX=3702 GN=HT1 PE=1 SV=1 Length=390 Score = 264 bits (674), Expect = 2e-77, Method: Composition-based stats. Identities = 85/335 (25%), Positives = 137/335 (41%), Gaps = 34/335 (10%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 + + + +V T + L G ++ Sbjct 44 ETMEKKRFDSMESWSMILESENVETWEASKGEREEWTADLSQLFIGNKFASGAHSRIYRG 103 Query 915 CYDPTNDGTGEMVAVKAL-----KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 Y VAVK + K + + +K E+ +L L+H +I+++ C + Sbjct 104 IYKQR------AVAVKMVRIPTHKEETRAKLEQQFKSEVALLSRLFHPNIVQFIAAC--K 155 Query 970 GEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 ++ EY+ G+LR YL + +S+ + +L A I GM YLH+Q IHRDL + Sbjct 156 KPPVYCIITEYMSQGNLRMYLNKKEPYSLSIETVLRLALDISRGMEYLHSQGVIHRDLKS 215 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 N+LL+++ VK+ DFG + + E + W APE +KE + DV+S Sbjct 216 NNLLLNDEMRVKVADFGTSCLETQCREA----KGNMGTYRWMAPEMIKEKPYTRKVDVYS 271 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 FG+ L+EL T QG V + E+ ER P P C + H Sbjct 272 FGIVLWELTTALLPF--------------QGMTPVQAAFAVAEKNERPPLPASCQPALAH 317 Query 1147 LMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 L+K CW S RP F N++ +L+ E + P Sbjct 318 LIKRCWSENPSKRPDFSNIVAVLEKYDECVKEGLP 352 Score = 219 bits (559), Expect = 8e-62, Method: Composition-based stats. Identities = 59/329 (18%), Positives = 118/329 (36%), Gaps = 37/329 (11%) Query 550 CCLPQPGET---SNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606 C P +T + M R L V+ E ++ Sbjct 29 PCNPSSSKTNRYAEAETMEKKRFDSMESWSMILESENVETWEASKGE-----------RE 77 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD------PSHHDIALAFYETAS 660 + S K R ++ V +K++ + + F + Sbjct 78 EWTADLSQLFIGNKFASGAHSRIYRGIYKQRAVAVKMVRIPTHKEETRAKLEQQFKSEVA 137 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLA 719 L+S++ H ++ C + P ++TEY+ G L ++L ++ + + + +A ++ Sbjct 138 LLSRLFHPNIVQFIAACKKPPVYCIITEYMSQGNLRMYLNKKEPYSLSIETVLRLALDIS 197 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERI 776 + YL ++ ++H ++ N+LL +K++D G + + Sbjct 198 RGMEYLHSQGVIHRDLKSNNLLLN-------DEMRVKVADFGTSCLETQCREAKGNMGTY 250 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF---YQRQHRL 833 W+APE + + +D + FG L E+ P Q +P + + L Sbjct 251 RWMAPEMIKE--KPYTRKVDVYSFGIVLWEL-TTALLPFQGMTPVQAAFAVAEKNERPPL 307 Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 P P LA L +C + P++RP F I Sbjct 308 PASCQPALAHLIKRCWSENPSKRPDFSNI 336 >sp|Q90330|FGFR4_COTCO Fibroblast growth factor receptor 4 OS=Coturnix coturnix OX=9091 GN=FGFR4 PE=2 SV=1 Length=713 Score = 273 bits (699), Expect = 3e-77, Method: Composition-based stats. Identities = 102/350 (29%), Positives = 156/350 (45%), Gaps = 38/350 (11%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 L Q + S +++R V D P F + L + L Sbjct 326 LIRQFSLDSSSSGKSSTSLMRVTRLSSSCAPMLAGVVEMDLPLDSKWEFPREKLVLGKPL 385 Query 904 GEGHFGKVSLYCYDPTND---GTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHI 959 GEG FG+V + VAVK LK + + + E+++++ + H++I Sbjct 386 GEGCFGQVVRAEAYGIDRQWPDRAVTVAVKMLKDNATDKDLADLISEMEMMKLMDKHKNI 445 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----------------PRHSIGLAQLLL 1002 I G C G L +++E+ G+LR+YL + L+ Sbjct 446 INLLGVCTQDG--PLYVIVEFAAKGNLREYLRARRPPTPDYTFDITELHEEQLCFKDLVS 503 Query 1003 FAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 Q+ GM YL ++ IHRDLAARNVL+ + ++KI DFGLA+ V +YY+ +G Sbjct 504 CVYQVARGMEYLESRRCIHRDLAARNVLVTAENVMKIADFGLARDV-HDIDYYKKTSNGR 562 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 PV W APE L + + + SDVWSFG+ ++E+ T L G + V Sbjct 563 LPVKWMAPEALFDRVYTHQSDVWSFGILMWEIFT--------------LGGSPYPGIPVE 608 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 L +LL+ G R+ P C E+Y LM+ CW RPTF+ L+ L + Sbjct 609 ELFKLLKEGHRMDCPSNCTHELYMLMRECWHAVPLQRPTFKQLVEGLDKI 658 Score = 232 bits (592), Expect = 4e-63, Method: Composition-based stats. Identities = 65/355 (18%), Positives = 126/355 (35%), Gaps = 51/355 (14%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 ++L S ++++ LG+G V + E + + Sbjct 363 EMDLPLDSKWEFPREKLVLGKPLGEGCFGQV-----------------VRAEAYGIDRQW 405 Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVS-HTHLAFVHGVCVRGPENIMVTEYV 690 + + V +K+L + D L +M + H ++ + GVC + ++ E+ Sbjct 406 PDRAVTVAVKMLKDNATDKDLADLISEMEMMKLMDKHKNIINLLGVCTQDGPLYVIVEFA 465 Query 691 EHGPLDVWLRRERGHVP---------------MAWKMVVAQQLASALSYLENKNLVHGNV 735 G L +LR R P + Q+A + YLE++ +H ++ Sbjct 466 AKGNLREYLRARRPPTPDYTFDITELHEEQLCFKDLVSCVYQVARGMEYLESRRCIHRDL 525 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGAN 789 RN+L+ + +K++D G+ + + + W+APE L Sbjct 526 AARNVLVTAENV-------MKIADFGLARDVHDIDYYKKTSNGRLPVKWMAPEALFDRV- 577 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847 + D W FG + EI G +P E + HR+ P +L L + Sbjct 578 -YTHQSDVWSFGILMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDCPSNCTHELYMLMRE 636 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902 C P QRP+F+ ++ L ++ + L ++ P+ D Sbjct 637 CWHAVPLQRPTFKQLVEGLDKILAAISEEYLDLSMPFEQYSPSCEDTTSTCSSDD 691 >sp|Q91571|EPB1A_XENLA Ephrin type-B receptor 1-A OS=Xenopus laevis OX=8355 GN=ephb1-a PE=1 SV=1 Length=985 Score = 279 bits (713), Expect = 4e-77, Method: Composition-based stats. Identities = 77/308 (25%), Positives = 144/308 (47%), Gaps = 21/308 (7%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 ++ + ++ ++K +G G FG+V + VA Sbjct 592 MKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPSKRE-ISVA 650 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 +K LKA + R + E I+ H +II+ +G + + ++ E++ G+L Sbjct 651 IKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKS--RPVMIITEFMENGALDS 708 Query 989 YLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 +L ++ + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL++ Sbjct 709 FLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 768 Query 1047 AVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 + + Y G PV W A E + KF ASDVWS+G+ ++E++++ + Sbjct 769 YLQDDTSDPTYTSSLGGKIPVRWTAQEAIAYRKFTSASDVWSYGIVMWEVMSYGER---- 824 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 M+ + +E+ RLP P CP ++ LM +CW+ + + RP Sbjct 825 ----------PYWTMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRLAE 874 Query 1165 LIPILKTV 1172 ++ L+ + Sbjct 875 IVNTLRPM 882 Score = 271 bits (694), Expect = 1e-74, Method: Composition-based stats. Identities = 76/363 (21%), Positives = 138/363 (38%), Gaps = 46/363 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G VY+GRL++ +E+ V + Sbjct 613 KEIDVSFVKIEEVIGAGEFGEVYKGRLKLPSK---------------------REISVAI 651 Query 642 KVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L F AS+M Q H ++ + GV + +++TE++E+G LD +LR Sbjct 652 KTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR 711 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD Sbjct 712 QNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 764 Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ +IP W A E + ++A D W +G + E+ G Sbjct 765 GLSRYLQDDTSDPTYTSSLGGKIPVRWTAQEAIA--YRKFTSASDVWSYGIVMWEVMSYG 822 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P + S + + ++ +RLP P CP L L C + RP I+ L + Sbjct 823 ERPYWTMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRLAEIVNTLRPM 882 Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG----E 925 + + + S P + + + + Y +G + Sbjct 883 IRNPASLKTVATIPAVPSQPLLDRSIPDISAFTSVDDWLSAIKMGQYRDNFLSSGFTSLQ 942 Query 926 MVA 928 +VA Sbjct 943 LVA 945 >sp|P53356|HTK16_HYDVU Tyrosine-protein kinase HTK16 OS=Hydra vulgaris OX=6087 GN=HTK16 PE=2 SV=1 Length=757 Score = 274 bits (700), Expect = 4e-77, Method: Composition-based stats. Identities = 110/363 (30%), Positives = 168/363 (46%), Gaps = 22/363 (6%) Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 + P+ P + + + PE + + + ++ + P + + T + Sbjct 399 KLPVPPSRPIKNNNGLPQPLPYPEFTNESDSDIFTRLECEKEKPLPKLPRPVVNHTEVPN 458 Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVK 930 + + K + ++LG G FG V + + G E+ VA+K Sbjct 459 SVNVGQKGDQTMKNNAQQNIILKESISFGKELGVGEFGSVIKGIW--LSPGGKEINVAMK 516 Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 L D Q + +E ++ L H I+ G C + LV E V +G+L DYL Sbjct 517 TLHKDKMVQGEKEFLREALVMSQLNHPCIVSLLGVCLGP---PMILVQELVEMGALLDYL 573 Query 991 PRHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + I L L+A QI GM YL + ++HRDLAARN+LL N + VKI DFGL++AV Sbjct 574 MDYQPEIQEVDLKLWASQIAFGMMYLELKRFVHRDLAARNILLANKKQVKISDFGLSRAV 633 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 G +YY+ ++ G PV WYAPE + F SDVWS+G+TL+E+ T D Sbjct 634 GTGSDYYQAKQGGRWPVRWYAPESINYGTFSTKSDVWSYGITLWEMFTFGD--------- 684 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 + G+MT + LE RL +PD+CP Y +M +CW + + RPTF L Sbjct 685 -----LPYGEMTGNEVVSFLEHCGRLEKPDECPIHTYSIMLSCWHIDPNKRPTFNELHST 739 Query 1169 LKT 1171 T Sbjct 740 FST 742 Score = 252 bits (643), Expect = 2e-69, Method: Composition-based stats. Identities = 82/352 (23%), Positives = 137/352 (39%), Gaps = 51/352 (14%) Query 531 AALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQ---------LSF 581 + D F+ C +P ++ P ++N+ Q Sbjct 418 LPYPEFTNESDSDIFTRLECEKEKPLPKLPRPVVNHTEV-PNSVNVGQKGDQTMKNNAQQ 476 Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + + ++ I+ LG G +V +G G G+E+ V + Sbjct 477 NIILKESISFGKELGVGEFGSVIKGIWLSPG---------------------GKEINVAM 515 Query 642 KVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L F A +MSQ++H + + GVC+ GP I+V E VE G L +L Sbjct 516 KTLHKDKMVQGEKEFLREALVMSQLNHPCIVSLLGVCL-GPPMILVQELVEMGALLDYLM 574 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + + + A Q+A + YLE K VH ++ RNILLA +K+SD Sbjct 575 DYQPEIQEVDLKLWASQIAFGMMYLELKRFVHRDLAARNILLANK-------KQVKISDF 627 Query 761 GVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ + + + + W APE + G + ST D W +G TL E+ G+ Sbjct 628 GLSRAVGTGSDYYQAKQGGRWPVRWYAPESINYG--TFSTKSDVWSYGITLWEMFTFGDL 685 Query 814 PLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 P + +E F + RL P+ ++ C +P +RP+F + Sbjct 686 PYGEMTGNEVVSFLEHCGRLEKPDECPIHTYSIMLSCWHIDPNKRPTFNELH 737 Score = 36.6 bits (83), Expect = 1.6, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 27/88 (31%), Gaps = 12/88 (14%) Query 450 GIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFP 506 HG + L DG +LI + P +L++ RS ++ F Sbjct 10 WYHGKITREVAVQVLLRKGGRDGFFLIRDCGNAPEDYVLSMMFRS---------QILHFQ 60 Query 507 IEQQDGAFVLEGWGRSFPSVRELGAALQ 534 I G F + L + + Sbjct 61 INCLGDNKFSIDNGPIFQGLDMLISYYK 88 >sp|Q9I8X3|FGFR3_DANRE Fibroblast growth factor receptor 3 OS=Danio rerio OX=7955 GN=fgfr3 PE=2 SV=1 Length=800 Score = 275 bits (703), Expect = 4e-77, Method: Composition-based stats. Identities = 101/304 (33%), Positives = 149/304 (49%), Gaps = 38/304 (13%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHR 941 P+ F + L + LGEG FG+V + + VAVK LK D + Sbjct 448 PSDPKWEFTRTKLTLGKPLGEGCFGQVVMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDL 507 Query 942 SGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---------- 990 S E+++++ + H++II G C G L +++EY G+LR+YL Sbjct 508 SDLVSEMEMMKMIGKHKNIINLLGACTQDG--PLYVLVEYASKGNLREYLRARRPPGMDY 565 Query 991 -------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 P ++ L+ A Q+ GM YL ++ IHRD AARNVL+ D ++KI DFG Sbjct 566 SFDTCKIPNETLTFKDLVSCAYQVARGMEYLASKKCIHRDPAARNVLVTEDNVMKIADFG 625 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 LA+ V +YY+ +G PV W APE L + + + SDVWS+GV L+E+ T Sbjct 626 LARDV-HNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSYGVLLWEIFT------- 677 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163 L G + V L +LL+ G R+ +P C E+Y +M+ CW S RPTF Sbjct 678 -------LGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFR 730 Query 1164 NLIP 1167 L+ Sbjct 731 QLVE 734 Score = 235 bits (599), Expect = 2e-63, Method: Composition-based stats. Identities = 80/370 (22%), Positives = 133/370 (36%), Gaps = 62/370 (17%) Query 545 FSLRRC--CLPQPGETSNLIIMRGARAS----PRTLNLSQLSFHRVDQKEITQLSH---- 594 F L+R SN ++R AR S P N+S+L + E T+ Sbjct 405 FPLKRQVSLESNSSMNSNTPLVRIARLSSSDGPMLPNVSELELPSDPKWEFTRTKLTLGK 464 Query 595 -LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LG+G V + E + + L V +K+L D L Sbjct 465 PLGEGCFGQV-----------------VMAEAIGIDKEKPNKPLTVAVKMLKDDGTDKDL 507 Query 654 -AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH------ 705 +M + H ++ + G C + ++ EY G L +LR R Sbjct 508 SDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSF 567 Query 706 ---------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 + + A Q+A + YL +K +H + RN+L+ + +K Sbjct 568 DTCKIPNETLTFKDLVSCAYQVARGMEYLASKKCIHRDPAARNVLVTEDNV-------MK 620 Query 757 LSDPGVGLGA----LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 ++D G+ ++ R+P W+APE L + D W +G L EI Sbjct 621 IADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRV--YTHQSDVWSYGVLLWEIFTL 678 Query 811 GEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 G +P E + HR+ P +L + +C P+QRP+FR ++ D R Sbjct 679 GGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFRQLVEDHDR 738 Query 869 LQPHNLADVL 878 + D Sbjct 739 VLSMTSTDEY 748 >sp|Q08881|ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=Homo sapiens OX=9606 GN=ITK PE=1 SV=1 Length=620 Score = 270 bits (690), Expect = 5e-77, Method: Composition-based stats. Identities = 84/430 (20%), Positives = 158/430 (37%), Gaps = 61/430 (14%) Query 449 DGIHGPLLEPFVQAKLRP--EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFP 506 + + + + L ++G +++ S + ++V ++ + ++ Sbjct 238 EWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTA-GTYTVSVFTKAVVSENNPCIKHYHIK 296 Query 507 IEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRG 566 + F S+ L Q G LR + G Sbjct 297 ETNDNPKRYYVAEKYVFDSIPLLINYHQHNG---GGLVTRLRYP------------VCFG 341 Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 + +P T L + +D E+T + +G G V+ G + Sbjct 342 RQKAPVTAGLRYGKWV-IDPSELTFVQEIGSGQFGLVHLGYWLNKD-------------- 386 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 +V +K + F E A +M ++SH L ++GVC+ +V Sbjct 387 -----------KVAIKTIREGAMS-EEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLV 434 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 E++EHG L +LR +RG + + + ++YLE ++H ++ RN L+ Sbjct 435 FEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLV---- 490 Query 747 LAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFG 801 G + IK+SD G+ L + + W +PE + S+ D W FG Sbjct 491 ---GENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFS--FSRYSSKSDVWSFG 545 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859 + E+ +G+ P ++RS SE RL P + + + + C P RP+F Sbjct 546 VLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAF 605 Query 860 RTILRDLTRL 869 +LR L + Sbjct 606 SRLLRQLAEI 615 Score = 254 bits (649), Expect = 2e-71, Method: Composition-based stats. Identities = 84/307 (27%), Positives = 132/307 (43%), Gaps = 27/307 (9%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 P V L ++++G G FG V L + + VA+ Sbjct 336 YPVCFGRQKAPVTAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKDK-----VAI 390 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K ++ G + +E +++ L H +++ G C +Q + LV E++ G L DY Sbjct 391 KTIRE--GAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQA--PICLVFEFMEHGCLSDY 446 Query 990 LP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 L R LL +CEGMAYL IHRDLAARN L+ ++++K+ DFG+ + Sbjct 447 LRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRF 506 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 V + + Y PV W +PE ++ SDVWSFGV ++E+ + Sbjct 507 VLD--DQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGK-------- 556 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 I + + E + G RL +P VY +M +CW+ RP F L+ Sbjct 557 ------IPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLR 610 Query 1168 ILKTVHE 1174 L + E Sbjct 611 QLAEIAE 617 >sp|Q8GXZ3|PBL8_ARATH Probable serine/threonine-protein kinase PBL8 OS=Arabidopsis thaliana OX=3702 GN=PBL8 PE=1 SV=1 Length=410 Score = 263 bits (672), Expect = 6e-77, Method: Composition-based stats. Identities = 84/287 (29%), Positives = 134/287 (47%), Gaps = 15/287 (5%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VAVKALKADCGPQHRSGWKQEIDILRT 953 + LGEG FG V Y N G VAVK L + HR W E++ L Sbjct 69 FRPDYILGEGGFGTVYKG-YIDDNLRVGLKSLPVAVKVLNKEGLQGHRE-WLTEVNFLGQ 126 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEG 1010 L H +++K G C + + LV E++ GSL ++L R + ++ ++ A +G Sbjct 127 LRHPNLVKLIGYCCEDDHR--LLVYEFMLRGSLENHLFRKTTAPLSWSRRMMIALGAAKG 184 Query 1011 MAYLHA--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +A+LH + I+RD N+LLD+D K+ DFGLAKA P+G E + V + Sbjct 185 LAFLHNAERPVIYRDFKTSNILLDSDYTAKLSDFGLAKAGPQGDETH-VSTRVMGTYGYA 243 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTE 1126 APE + SDV+SFGV L E+LT S ++ P+K L+ A+ ++ R L + Sbjct 244 APEYVMTGHLTARSDVYSFGVVLLEMLTGRKSVDKTRPSKEQNLVDWARPKLNDKRKLLQ 303 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 +++ + + L C RP +++ L+ + Sbjct 304 IIDPRLENQYSVRAAQKACSLAYYCLSQNPKARPLMSDVVETLEPLQ 350 Score = 236 bits (601), Expect = 3e-67, Method: Composition-based stats. Identities = 73/386 (19%), Positives = 135/386 (35%), Gaps = 60/386 (16%) Query 547 LRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606 L P+ + S R + + + + + K LG+G VY+G Sbjct 33 LSDPSTPRFRDDS-----RTPISYAQVIPFTLFELETI-TKSFRPDYILGEGGFGTVYKG 86 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS 666 + R + L V +KVL+ + + + Q+ Sbjct 87 YIDDNL------------------RVGLKSLPVAVKVLNKEGLQGHREWLTEVNFLGQLR 128 Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYL 725 H +L + G C ++V E++ G L+ L R+ + + +M++A A L++L Sbjct 129 HPNLVKLIGYCCEDDHRLLVYEFMLRGSLENHLFRKTTAPLSWSRRMMIALGAAKGLAFL 188 Query 726 EN--KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIP 777 N + +++ + NILL + KLSD G+ +E + Sbjct 189 HNAERPVIYRDFKTSNILLD-------SDYTAKLSDFGLAKAGPQGDETHVSTRVMGTYG 241 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS 837 + APE + G L+ D + FG LLE+ ++ ++R E+ + +L + Sbjct 242 YAAPEYVMTG--HLTARSDVYSFGVVLLEMLTGRKSVDKTRPSKEQNLVDWARPKLNDKR 299 Query 838 ------CPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 P+L +L CL+ P RP ++ L LQ A + Sbjct 300 KLLQIIDPRLENQYSVRAAQKACSLAYYCLSQNPKARPLMSDVVETLEPLQCTGDALIPC 359 Query 880 VNPDSPASDPTVFHKRYLKKIRDLGE 905 + A+ Y R Sbjct 360 ATTTAGAAFAMGGVPDYRMHRRFAKN 385 >sp|Q5PP29|PBL4_ARATH Probable serine/threonine-protein kinase PBL4 OS=Arabidopsis thaliana OX=3702 GN=PBL4 PE=2 SV=1 Length=412 Score = 263 bits (672), Expect = 6e-77, Method: Composition-based stats. Identities = 86/286 (30%), Positives = 128/286 (45%), Gaps = 13/286 (5%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +GEG FG V D P+ G+G +VAVK LK + HR W E+D L L+H Sbjct 89 IGEGGFGYVYKGWIDERTLSPSKPGSGMVVAVKKLKEEGFQGHRQ-WLAEVDCLGRLHHM 147 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYL 1014 +++K G C L LV EY+P GSL ++L R I + A G+A+L Sbjct 148 NLVKLIGYCSKGDHIRL-LVYEYMPKGSLENHLFRRGAEPIPWRTRIKVAIGAARGLAFL 206 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H I+RD A N+LLD++ K+ DFGLAK P G + V + APE + Sbjct 207 HEAQVIYRDFKASNILLDSEFNAKLSDFGLAKVGPTGDRTH-VSTQVMGTQGYAAPEYVA 265 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQM-TVLRLTELLERGE 1132 + SDV+SFGV L ELL+ + L+ A + ++ +++ Sbjct 266 TGRITAKSDVYSFGVVLLELLSGRLTVDKTKVGVERNLVDWAIPYLGDKRKVFRIMDTKL 325 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P K C + C E RP +++ L+ + + Sbjct 326 GGQYPHKGACLTANTALQCLNQEPKLRPKMSDVLSTLEELEMTLKS 371 Score = 233 bits (594), Expect = 3e-66, Method: Composition-based stats. Identities = 67/333 (20%), Positives = 116/333 (35%), Gaps = 50/333 (15%) Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 G + TL + + + S +G+G VY+G + DE Sbjct 59 EGELLASPTLKAFTFNELKTATRNFRPDSVIGEGGFGYVYKGWI--------------DE 104 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE-N 683 L P + G + V +K L + + ++ H +L + G C +G Sbjct 105 RTLSPSKP-GSGMVVAVKKLKEEGFQGHRQWLAEVDCLGRLHHMNLVKLIGYCSKGDHIR 163 Query 684 IMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 ++V EY+ G L+ L R +P ++ VA A L++L +++ + NILL Sbjct 164 LLVYEYMPKGSLENHLFRRGAEPIPWRTRIKVAIGAARGLAFLHEAQVIYRDFKASNILL 223 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMD 796 + KLSD G+ + + + + APE + G ++ D Sbjct 224 D-------SEFNAKLSDFGLAKVGPTGDRTHVSTQVMGTQGYAAPEYVATG--RITAKSD 274 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR------------------QHRLPEPSC 838 + FG LLE+ +++ E+ + P Sbjct 275 VYSFGVVLLELLSGRLTVDKTKVGVERNLVDWAIPYLGDKRKVFRIMDTKLGGQYPHKGA 334 Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 A QCL EP RP +L L L+ Sbjct 335 CLTANTALQCLNQEPKLRPKMSDVLSTLEELEM 367 >sp|Q9LFP7|PBL34_ARATH Serine/threonine-protein kinase PBL34 OS=Arabidopsis thaliana OX=3702 GN=PBL34 PE=1 SV=1 Length=493 Score = 266 bits (679), Expect = 8e-77, Method: Composition-based stats. Identities = 88/282 (31%), Positives = 130/282 (46%), Gaps = 16/282 (6%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LGEG FG V + P GTG VAVK L D G Q W EI+ L L H Sbjct 148 LGEGGFGCVFKGWIEENGTAPVKPGTGLTVAVKTLNPD-GLQGHKEWLAEINFLGNLLHP 206 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLLFAQQICEGMAYLH 1015 +++K G C + ++ LV E++P GSL ++L R S+ + + A +G+++LH Sbjct 207 NLVKLVGYCIEDDQR--LLVYEFMPRGSLENHLFRRSLPLPWSIRMKIALGAAKGLSFLH 264 Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 + I+RD N+LLD D K+ DFGLAK P+ + + V + APE Sbjct 265 EEALKPVIYRDFKTSNILLDADYNAKLSDFGLAKDAPDEGKTH-VSTRVMGTYGYAAPEY 323 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQ-MTVLRLTELLER 1130 + SDV+SFGV L E+LT S ++ P L+ A+ + R LL+ Sbjct 324 VMTGHLTSKSDVYSFGVVLLEMLTGRRSMDKNRPNGEHNLVEWARPHLLDKRRFYRLLDP 383 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 K +V L C + RP +++ LK + Sbjct 384 RLEGHFSIKGAQKVTQLAAQCLSRDPKIRPKMSDVVEALKPL 425 Score = 256 bits (655), Expect = 1e-73, Method: Composition-based stats. Identities = 66/356 (19%), Positives = 126/356 (35%), Gaps = 51/356 (14%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 +S+ ++ L + ++ + S LG+G V++G + G+ + Sbjct 111 SSSTPVISEELNISSHLRKFTFNDLKLSTRNFRPESLLGEGGFGCVFKGWIEENGTAPVK 170 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 G L V +K L+P + + + + H +L + G C Sbjct 171 P---------------GTGLTVAVKTLNPDGLQGHKEWLAEINFLGNLLHPNLVKLVGYC 215 Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGN 734 + + ++V E++ G L+ L R +P + +M +A A LS+L K +++ + Sbjct 216 IEDDQRLLVYEFMPRGSLENHLFRRSLPLPWSIRMKIALGAAKGLSFLHEEALKPVIYRD 275 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGA 788 NILL KLSD G+ A + + APE + G Sbjct 276 FKTSNILLD-------ADYNAKLSDFGLAKDAPDEGKTHVSTRVMGTYGYAAPEYVMTG- 327 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS----------- 837 L++ D + FG LLE+ + ++R E + L + Sbjct 328 -HLTSKSDVYSFGVVLLEMLTGRRSMDKNRPNGEHNLVEWARPHLLDKRRFYRLLDPRLE 386 Query 838 -------CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 ++ L +QCL+ +P RP ++ L L + + Sbjct 387 GHFSIKGAQKVTQLAAQCLSRDPKIRPKMSDVVEALKPLPHLKDMASSSYYFQTMQ 442 >sp|P41242|MATK_MOUSE Megakaryocyte-associated tyrosine-protein kinase OS=Mus musculus OX=10090 GN=Matk PE=1 SV=2 Length=505 Score = 266 bits (679), Expect = 8e-77, Method: Composition-based stats. Identities = 105/354 (30%), Positives = 160/354 (45%), Gaps = 44/354 (12%) Query 821 SEKEHFY--QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + H+ R L L + T+L Sbjct 162 RDVIHYRVLHRDGHLTIDEAVCFCNLMDM-------VEHYTKDKGAICTKLVKPRRKQGA 214 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 + A + ++L +GEG FG V Y G+ VAVK +K D Sbjct 215 KSAEEELAKAGWLLDLQHLTLGAQIGEGEFGAVLQGEYL------GQKVAVKNIKCDVTA 268 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---I 995 Q + E ++ L H ++++ G G L +VME+V G+L ++L + Sbjct 269 Q---AFLDETAVMTKLQHRNLVRLLGVILHHG---LYIVMEHVSKGNLVNFLRTRGRALV 322 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 +QLL FA + EGM YL ++ +HRDLAARN+L+ D + K+ DFGLAKA +G + Sbjct 323 STSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSS 382 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 R+ PV W APE LK +F SDVWSFGV L+E+ ++ + Sbjct 383 RL------PVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRA--------------P 422 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 +M++ ++E +E+G R+ PD CP V+ LM +CWE E + RP F ++ L Sbjct 423 YPKMSLKEVSEAVEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRKIVEKL 476 Score = 262 bits (670), Expect = 2e-75, Method: Composition-based stats. Identities = 98/422 (23%), Positives = 166/422 (39%), Gaps = 70/422 (17%) Query 446 SIRDGIHGPLLEPFVQAKLRP-EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 S+ HG + +L+P EDGL+L+ S HP +L V+ Sbjct 116 SLMPWFHGKISGQEAIQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVI---------H 166 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + + +DG ++ F ++ ++ G C L + Q +++ + Sbjct 167 YRVLHRDGHLTID-EAVCFCNLMDMVEHYTKDK---GAICTKLVKPRRKQGAKSAEEELA 222 Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 + +D + +T + +G+G V +G + Sbjct 223 KAG--------------WLLDLQHLTLGAQIGEGEFGAVLQGEYLGQ------------- 255 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 +V +K + A AF + ++M+++ H +L + GV + Sbjct 256 -------------KVAVKNIKCDVT--AQAFLDETAVMTKLQHRNLVRLLGVILHHG-LY 299 Query 685 MVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 +V E+V G L +LR R R V + + A +A + YLE+K LVH ++ RNIL++ Sbjct 300 IVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVS 359 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSR-EERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 +A K+SD G+ + + W APE L G S+ D W FG Sbjct 360 EDLVA-------KVSDFGLAKAERKGLDSSRLPVKWTAPEALKNG--RFSSKSDVWSFGV 410 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFR 860 L E+ G AP S E ++ +R+ P CP + TL C EP +RP FR Sbjct 411 LLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFR 470 Query 861 TI 862 I Sbjct 471 KI 472 >sp|O73878|EPB4B_DANRE Ephrin type-B receptor 4b OS=Danio rerio OX=7955 GN=ephb4b PE=1 SV=2 Length=976 Score = 277 bits (709), Expect = 9e-77, Method: Composition-based stats. Identities = 82/327 (25%), Positives = 139/327 (43%), Gaps = 21/327 (6%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 T P ++ + ++ ++K +G G FG Sbjct 566 TRRRDPDPDKSGQFLMGQGIKVYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFG 625 Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 +V VA+K LK + R + E I+ H +II +G Sbjct 626 EVCRGRLKVPGKKEN-YVAIKTLKGGYTDKQRRDFLSEASIMGQFQHPNIIHLEGVIT-- 682 Query 970 GEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027 + ++ EY+ G+L +L QL+ + I GM YL ++HRDLAAR Sbjct 683 ASCPVMILTEYMENGALDSFLRLNDGQFTPIQLVGMLRGIASGMKYLSEMSFVHRDLAAR 742 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 N+L++++ + K+ DFGL++ + E Y G P+ W APE + KF ASDVW Sbjct 743 NILVNSNLVCKVSDFGLSRFLTENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDVW 802 Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 S+G+ ++E+++ + M+ + +E+ RLP P +CP ++ Sbjct 803 SYGIVMWEVMSFGER--------------PYWDMSNQDVINAIEQDYRLPPPPECPASLH 848 Query 1146 HLMKNCWETEASFRPTFENLIPILKTV 1172 LM +CW+ E S RP F ++ L + Sbjct 849 QLMLDCWQKERSSRPRFCAIVSALDRL 875 Score = 263 bits (671), Expect = 1e-71, Method: Composition-based stats. Identities = 78/304 (26%), Positives = 123/304 (40%), Gaps = 42/304 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G V GRL+V G +E V + Sbjct 606 KEIDVSFVKIEEVIGAGEFGEVCRGRLKVPGK---------------------KENYVAI 644 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + D F AS+M Q H ++ + GV +++TEY+E+G LD +LR Sbjct 645 KTLKGGYTDKQRRDFLSEASIMGQFQHPNIIHLEGVITASCPVMILTEYMENGALDSFLR 704 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G + + + +AS + YL + VH ++ RNIL+ ++ K+SD Sbjct 705 LNDGQFTPIQLVGMLRGIASGMKYLSEMSFVHRDLAARNILVN-------SNLVCKVSDF 757 Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ +IP W APE + ++A D W +G + E+ G Sbjct 758 GLSRFLTENSSDPTYTSSLGGKIPIRWTAPEAIA--FRKFTSASDVWSYGIVMWEVMSFG 815 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P S + + ++ +RLP P CP L L C E + RP F I+ L RL Sbjct 816 ERPYWDMSNQDVINAIEQDYRLPPPPECPASLHQLMLDCWQKERSSRPRFCAIVSALDRL 875 Query 870 QPHN 873 + Sbjct 876 IRNP 879 >sp|P54761|EPHB4_MOUSE Ephrin type-B receptor 4 OS=Mus musculus OX=10090 GN=Ephb4 PE=1 SV=2 Length=987 Score = 278 bits (710), Expect = 9e-77, Method: Composition-based stats. Identities = 82/333 (25%), Positives = 140/333 (42%), Gaps = 25/333 (8%) Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE-- 905 CL + R + + + + P F K + E Sbjct 562 CLRKQSNGREVEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVREFAKEIDVSYVKIEEVI 621 Query 906 --GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963 G FG+V VA+K LK + R + E I+ H +II+ + Sbjct 622 GAGEFGEVCRGRLKAPGKKES-CVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLE 680 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G + ++ E++ G+L +L + QL+ + I GM YL Y+H Sbjct 681 GVVT--NSVPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYVH 738 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFY 1079 RDLAARN+L++++ + K+ DFGL++ + E Y G P+ W APE + KF Sbjct 739 RDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFT 798 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 ASD WS+G+ ++E+++ + M+ + +E+ RLP P Sbjct 799 SASDAWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIEQDYRLPPPPD 844 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 CP ++ LM +CW+ + + RP F ++ L + Sbjct 845 CPTSLHQLMLDCWQKDRNARPRFPQVVSALDKM 877 Score = 261 bits (668), Expect = 2e-71, Method: Composition-based stats. Identities = 77/362 (21%), Positives = 136/362 (38%), Gaps = 60/362 (17%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G V GRL+ G +E V + Sbjct 608 KEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGK---------------------KESCVAI 646 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV +++TE++E+G LD +LR Sbjct 647 KTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSVPVMILTEFMENGALDSFLR 706 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G + + + + +AS + YL + VH ++ RNIL+ ++ K+SD Sbjct 707 LNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVN-------SNLVCKVSDF 759 Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ +IP W APE + ++A D W +G + E+ G Sbjct 760 GLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIA--FRKFTSASDAWSYGIVMWEVMSFG 817 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P S + + ++ +RLP P L L C + RP F ++ L ++ Sbjct 818 ERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKM 877 Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 + + + + AS P + ++ FG V + A+ Sbjct 878 IRNPASLKIVARENGGASHPLLDQRQPHYS-------AFGSVGEWLR-----------AI 919 Query 930 KA 931 K Sbjct 920 KM 921 >sp|Q63604|NTRK2_RAT BDNF/NT-3 growth factors receptor OS=Rattus norvegicus OX=10116 GN=Ntrk2 PE=1 SV=1 Length=821 Score = 274 bits (701), Expect = 9e-77, Method: Composition-based stats. Identities = 110/334 (33%), Positives = 160/334 (48%), Gaps = 33/334 (10%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914 P I + + +T + P + + + R+LGEG FGKV L Sbjct 496 GPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAE 555 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 CY+ + +VAVK LK D R + +E ++L L HEHI+K+ G C + L Sbjct 556 CYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGD--PL 612 Query 975 QLVMEYVPLGSLRDYLPRHS--------------IGLAQLLLFAQQICEGMAYLHAQHYI 1020 +V EY+ G L +L H + +Q+L AQQI GM YL +QH++ Sbjct 613 IMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFV 672 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + KF Sbjct 673 HRDLATRNCLVGENLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRKFTT 731 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS GV L+E+ T+ Q++ + E + +G L RP C Sbjct 732 ESDVWSLGVVLWEIFTYGKQ--------------PWYQLSNNEVIECITQGRVLQRPRTC 777 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 P EVY LM CW+ E R +N+ +L+ + + Sbjct 778 PQEVYELMLGCWQREPHTRKNIKNIHTLLQNLAK 811 Score = 266 bits (679), Expect = 8e-74, Method: Composition-based stats. Identities = 72/306 (24%), Positives = 123/306 (40%), Gaps = 48/306 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + + I LG+G V+ + + L P +D+ + V +K Sbjct 532 IKRHNIVLKRELGEGAFGKVF----------------LAECYNLCPEQDK---ILVAVKT 572 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--- 700 L + + F+ A L++ + H H+ +GVCV G IMV EY++HG L+ +LR Sbjct 573 LKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 632 Query 701 ---------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 + + + +AQQ+A+ + YL +++ VH ++ RN L+ G Sbjct 633 PDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV-------GE 685 Query 752 SPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + +K+ D G+ S + + I W+ PE + +T D W G L Sbjct 686 NLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSLGVVLW 743 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 EI G+ P S +E + L P ++ L C EP R + + I Sbjct 744 EIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHTRKNIKNIH 803 Query 864 RDLTRL 869 L L Sbjct 804 TLLQNL 809 >sp|P54753|EPHB3_HUMAN Ephrin type-B receptor 3 OS=Homo sapiens OX=9606 GN=EPHB3 PE=1 SV=2 Length=998 Score = 278 bits (710), Expect = 9e-77, Method: Composition-based stats. Identities = 80/333 (24%), Positives = 146/333 (44%), Gaps = 26/333 (8%) Query 848 CLTYE---PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 CL + + + ++ + ++ +K +G Sbjct 581 CLRKQRHGSDSEYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIG 640 Query 905 EGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963 G FG+V G E+ VA+K LK + R + E I+ H +II+ + Sbjct 641 AGEFGEVCRGRLK--QPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLE 698 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 G + + ++ E++ +L +L + QL+ + I GM YL +Y+H Sbjct 699 GVVTKS--RPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVH 756 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKFY 1079 RDLAARN+L++++ + K+ DFGL++ + + Y G P+ W APE + KF Sbjct 757 RDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFT 816 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 ASDVWS+G+ ++E++++ + M+ + +E+ RLP P Sbjct 817 SASDVWSYGIVMWEVMSYGER--------------PYWDMSNQDVINAVEQDYRLPPPMD 862 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 CP ++ LM +CW + + RP F ++ L + Sbjct 863 CPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKL 895 Score = 261 bits (667), Expect = 4e-71, Method: Composition-based stats. Identities = 76/348 (22%), Positives = 133/348 (38%), Gaps = 42/348 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G V GRL+ G +E+ V + Sbjct 626 KEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGR---------------------REVFVAI 664 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + +++TE++E+ LD +LR Sbjct 665 KTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLR 724 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD Sbjct 725 LNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 777 Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ +IP W APE + ++A D W +G + E+ G Sbjct 778 GLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYG 835 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P S + + ++ +RLP P CP L L C + RP F I+ L +L Sbjct 836 ERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKL 895 Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917 + + + + S S P + + + Y Sbjct 896 IRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYK 943 >sp|P00529|ROS_AVISU Tyrosine-protein kinase transforming protein ros OS=UR2 avian sarcoma virus OX=354090 GN=V-ROS PE=3 SV=1 Length=402 Score = 262 bits (669), Expect = 1e-76, Method: Composition-based stats. Identities = 99/287 (34%), Positives = 137/287 (48%), Gaps = 33/287 (11%) Query 903 LGEGHFGKVSLYC-YDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG G FG+V D DG+GE VAVK LK Q +S + +E ++ H HI+ Sbjct 104 LGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMSKFDHPHIL 163 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--------LLLFAQQICEGMA 1012 K G C + L++E + G L YL Q LL IC+G Sbjct 164 KLLGVCLLNEPQ--YLILELMEGGDLLSYLRGARKQKFQSPLLTLTDLLDICLDICKGCV 221 Query 1013 YLHAQHYIHRDLAARNVLLDND------RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 YL +IHRDLAARN L+ R+VKIGDFGLA+ + + ++YYR R +G PV Sbjct 222 YLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYK-NDYYRKRGEGLLPVR 280 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE L + F SDVW+FGV ++E LT L ++ + + Sbjct 281 WMAPESLIDGVFTNHSDVWAFGVLVWETLT--------------LGQQPYPGLSNIEVLH 326 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + G RL P+ CP ++ LM CW + RPTF + L+ + Sbjct 327 HVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEIR 373 Score = 256 bits (653), Expect = 2e-74, Method: Composition-based stats. Identities = 73/315 (23%), Positives = 114/315 (36%), Gaps = 36/315 (11%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 S + ++ LG G VYEG L D E RV Sbjct 89 SLPAFPRDKLNLHKLLGSGAFGEVYEG------------------TALDILADGSGESRV 130 Query 640 VLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +K L D F + A LMS+ H H+ + GVC+ ++ E +E G L + Sbjct 131 AVKTLKRGATDQEKSEFLKEAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSY 190 Query 699 LRRERGH------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752 LR R + + + + + YLE +H ++ RN L++ S Sbjct 191 LRGARKQKFQSPLLTLTDLLDICLDICKGCVYLEKMRFIHRDLAARNCLVSEKQYGSC-S 249 Query 753 PFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 +K+ D G+ + +R + W+APE L G + D W FG + E Sbjct 250 RVVKIGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLIDGV--FTNHSDVWAFGVLVWE 307 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 G+ P S E H + RL P + L ++C +P RP+F I Sbjct 308 TLTLGQQPYPGLSNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQH 367 Query 865 DLTRLQPHNLADVLT 879 L ++ L Sbjct 368 KLQEIRHSPLCFSYF 382 >sp|Q65XV8|RK176_ORYSJ Receptor-like cytoplasmic kinase 176 OS=Oryza sativa subsp. japonica OX=39947 GN=RLCK176 PE=1 SV=1 Length=395 Score = 261 bits (668), Expect = 1e-76, Method: Composition-based stats. Identities = 89/292 (30%), Positives = 137/292 (47%), Gaps = 18/292 (6%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LGEG FG V D PT GTG ++AVK L + HR W E++ L L H Sbjct 76 LGEGGFGSVFKGWIDEKTLAPTKPGTGMVIAVKKLNQEGHQGHRE-WLAEVNYLGQLSHP 134 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMA 1012 ++++ G C + ++ LV E++P GSL ++L R S + + A +G+A Sbjct 135 YLVRLVGYCVEDEQR--LLVYEFMPRGSLENHLFRRSTHFQPLSWNLRMKIALGAAKGLA 192 Query 1013 YLHAQHY--IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 +LH+ I+RD NVLLD + K+ DFGLAK P G + + V + AP Sbjct 193 FLHSDKVKVIYRDFKTSNVLLDANYDAKLSDFGLAKDGPTGDKSH-VSTRVMGTYGYAAP 251 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQG-QMTVLRLTELL 1128 E L SDV+SFGV L E+L+ + ++ PT L+ A+ M+ R+ +L Sbjct 252 EYLATGHLTTKSDVYSFGVVLLEMLSGRRALDKNRPTGEHNLVEWARPYLMSKRRIFRIL 311 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180 + + L C EA RP E ++ +L+ + + + A Sbjct 312 DARLGGQYSLAKAQKAATLALQCISVEAKNRPNMEQVVAVLEQLQDSKETGA 363 Score = 239 bits (609), Expect = 2e-68, Method: Composition-based stats. Identities = 76/348 (22%), Positives = 138/348 (40%), Gaps = 60/348 (17%) Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 P P ++ A+ + ++L R + S LG+G +V++G + Sbjct 40 PPTPRSEDEILEA----ANVKAFAFNEL---RTATRNFRPDSVLGEGGFGSVFKGWI--- 89 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 DE L P + G + + +K L+ H + + + Q+SH +L Sbjct 90 -----------DEKTLAPTKP-GTGMVIAVKKLNQEGHQGHREWLAEVNYLGQLSHPYLV 137 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV-PMAW--KMVVAQQLASALSYLENK 728 + G CV + ++V E++ G L+ L R H P++W +M +A A L++L + Sbjct 138 RLVGYCVEDEQRLLVYEFMPRGSLENHLFRRSTHFQPLSWNLRMKIALGAAKGLAFLHSD 197 Query 729 --NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLA 780 +++ + N+LL + KLSD G+ + ++ + + A Sbjct 198 KVKVIYRDFKTSNVLLD-------ANYDAKLSDFGLAKDGPTGDKSHVSTRVMGTYGYAA 250 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGE-----APLQSRSPSEKEH-FYQRQHRLP 834 PE L G L+T D + FG LLE+ P + E + + R+ Sbjct 251 PEYLATG--HLTTKSDVYSFGVVLLEMLSGRRALDKNRPTGEHNLVEWARPYLMSKRRIF 308 Query 835 EPSCPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 +L ATL QC++ E RP+ ++ L +LQ Sbjct 309 RILDARLGGQYSLAKAQKAATLALQCISVEAKNRPNMEQVVAVLEQLQ 356 >sp|P08630|BTKL_DROME Tyrosine-protein kinase Btk OS=Drosophila melanogaster OX=7227 GN=Btk PE=2 SV=2 Length=786 Score = 273 bits (698), Expect = 1e-76, Method: Composition-based stats. Identities = 96/363 (26%), Positives = 154/363 (42%), Gaps = 29/363 (8%) Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 ++ + + + + + + + C P R L + D Sbjct 449 HTKVPQSHVKHYHIKQNARCEYYLSEKHCCETIPDLINYHRHNSGGLACRLKSSPCDRPV 508 Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 + D H L + +LG G FG V + + D AVK +K G Sbjct 509 PPTAGLSHDKWEIHPMELMLMEELGSGQFGVVRRGKWRGSIDT-----AVKMMKE--GTM 561 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL-- 997 + +E ++ L H ++++ G C + + +V EY+ GSL +YL RH L Sbjct 562 SEDDFIEEAKVMTKLQHPNLVQLYGVCSK--HRPIYIVTEYMKHGSLLNYLRRHEKTLIG 619 Query 998 --AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 LL Q+ +GM YL +YIHRDLAARN L+ ++ +VK+ DFGLA+ V + + Y Sbjct 620 NMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYVLD--DQY 677 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 P+ W PE L +F SDVW++GV ++E+ T + Sbjct 678 TSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGK--------------MP 723 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 G++ + E ++RG L +P C E+Y +MK CW RP F L+ L V + Sbjct 724 YGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLALVAQT 783 Query 1176 YQG 1178 Sbjct 784 LTD 786 Score = 268 bits (685), Expect = 7e-75, Method: Composition-based stats. Identities = 85/440 (19%), Positives = 162/440 (37%), Gaps = 72/440 (16%) Query 438 VAPPRLV-MSIRDGIHGPLLEPFVQAKLRP--EDGLYLIHWSTSHPYRLILTVAQRSQAP 494 V P L+ + + G + ++ L+ ++G +++ S++ L++ + Sbjct 397 VKPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTK-GLYTLSLHTKVPQS 455 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 ++ + I+Q ++ +L + G C C Sbjct 456 ------HVKHYHIKQNARCEYYLSEKHCCETIPDLINYHRHNS--GGLACRLKSSPC--- 504 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 R P T LS + E+ + LG G V G+ R Sbjct 505 ------------DRPVPPTAGLSH-DKWEIHPMELMLMEELGSGQFGVVRRGKWRGS--- 548 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 + +K++ F E A +M+++ H +L ++ Sbjct 549 ----------------------IDTAVKMMKEGTMS-EDDFIEEAKVMTKLQHPNLVQLY 585 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGHV--PMAWKMVVAQQLASALSYLENKNLVH 732 GVC + +VTEY++HG L +LRR + M + + Q++ ++YLE N +H Sbjct 586 GVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIH 645 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGG 787 ++ RN L+ G+ +K++D G+ L + I W PE L Sbjct 646 RDLAARNCLV-------GSENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVL--N 696 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLT 845 S+ D W +G + EI G+ P +E QR L P+ ++ + Sbjct 697 YTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVM 756 Query 846 SQCLTYEPTQRPSFRTILRD 865 C ++ P +RP+FR ++ Sbjct 757 KLCWSHGPEERPAFRVLMDQ 776 >sp|P15209|NTRK2_MOUSE BDNF/NT-3 growth factors receptor OS=Mus musculus OX=10090 GN=Ntrk2 PE=1 SV=1 Length=821 Score = 274 bits (700), Expect = 1e-76, Method: Composition-based stats. Identities = 109/334 (33%), Positives = 160/334 (48%), Gaps = 33/334 (10%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914 P I + + +T + P + + + R+LGEG FGKV L Sbjct 496 GPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAE 555 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 CY+ + +VAVK LK D R + +E ++L L HEHI+K+ G C + L Sbjct 556 CYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGD--PL 612 Query 975 QLVMEYVPLGSLRDYLPRHS--------------IGLAQLLLFAQQICEGMAYLHAQHYI 1020 +V EY+ G L +L H + +Q+L AQQI GM YL +QH++ Sbjct 613 IMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFV 672 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + KF Sbjct 673 HRDLATRNCLVGENLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRKFTT 731 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS GV L+E+ T+ Q++ + E + +G L RP C Sbjct 732 ESDVWSLGVVLWEIFTYGKQ--------------PWYQLSNNEVIECITQGRVLQRPRTC 777 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 P EVY LM CW+ E R +++ +L+ + + Sbjct 778 PQEVYELMLGCWQREPHTRKNIKSIHTLLQNLAK 811 Score = 266 bits (679), Expect = 8e-74, Method: Composition-based stats. Identities = 72/306 (24%), Positives = 124/306 (41%), Gaps = 48/306 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + + I LG+G V+ + + L P +D+ + V +K Sbjct 532 IKRHNIVLKRELGEGAFGKVF----------------LAECYNLCPEQDK---ILVAVKT 572 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--- 700 L + + F+ A L++ + H H+ +GVCV G IMV EY++HG L+ +LR Sbjct 573 LKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 632 Query 701 ---------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 + + + +AQQ+A+ + YL +++ VH ++ RN L+ G Sbjct 633 PDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV-------GE 685 Query 752 SPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + +K+ D G+ S + + I W+ PE + +T D W G L Sbjct 686 NLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSLGVVLW 743 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 EI G+ P S +E + L P ++ L C EP R + ++I Sbjct 744 EIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHTRKNIKSIH 803 Query 864 RDLTRL 869 L L Sbjct 804 TLLQNL 809 >sp|Q16620|NTRK2_HUMAN BDNF/NT-3 growth factors receptor OS=Homo sapiens OX=9606 GN=NTRK2 PE=1 SV=1 Length=822 Score = 274 bits (700), Expect = 1e-76, Method: Composition-based stats. Identities = 109/334 (33%), Positives = 159/334 (48%), Gaps = 33/334 (10%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914 P I + + +T + P + + + R+LGEG FGKV L Sbjct 497 GPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAE 556 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 CY+ + +VAVK LK D R + +E ++L L HEHI+K+ G C + L Sbjct 557 CYNLCPEQDKILVAVKTLK-DASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGD--PL 613 Query 975 QLVMEYVPLGSLRDYLPRHS--------------IGLAQLLLFAQQICEGMAYLHAQHYI 1020 +V EY+ G L +L H + +Q+L AQQI GM YL +QH++ Sbjct 614 IMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFV 673 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLA RN L+ + LVKIGDFG+++ V +YYRV P+ W PE + KF Sbjct 674 HRDLATRNCLVGENLLVKIGDFGMSRDVY-STDYYRVGGHTMLPIRWMPPESIMYRKFTT 732 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS GV L+E+ T+ Q++ + E + +G L RP C Sbjct 733 ESDVWSLGVVLWEIFTYGKQ--------------PWYQLSNNEVIECITQGRVLQRPRTC 778 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 P EVY LM CW+ E R + + +L+ + + Sbjct 779 PQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAK 812 Score = 266 bits (679), Expect = 8e-74, Method: Composition-based stats. Identities = 72/306 (24%), Positives = 123/306 (40%), Gaps = 48/306 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + + I LG+G V+ + + L P +D+ + V +K Sbjct 533 IKRHNIVLKRELGEGAFGKVF----------------LAECYNLCPEQDK---ILVAVKT 573 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--- 700 L + + F+ A L++ + H H+ +GVCV G IMV EY++HG L+ +LR Sbjct 574 LKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHG 633 Query 701 ---------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 + + + +AQQ+A+ + YL +++ VH ++ RN L+ G Sbjct 634 PDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV-------GE 686 Query 752 SPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + +K+ D G+ S + + I W+ PE + +T D W G L Sbjct 687 NLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM--YRKFTTESDVWSLGVVLW 744 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 EI G+ P S +E + L P ++ L C EP R + + I Sbjct 745 EIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIH 804 Query 864 RDLTRL 869 L L Sbjct 805 TLLQNL 810 >sp|Q54H46|DRKA_DICDI Probable serine/threonine-protein kinase drkA OS=Dictyostelium discoideum OX=44689 GN=drkA PE=3 SV=1 Length=642 Score = 269 bits (688), Expect = 2e-76, Method: Composition-based stats. Identities = 77/304 (25%), Positives = 132/304 (43%), Gaps = 34/304 (11%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 N + D +K +G+G++G+V L + G VAVK L A Sbjct 352 YYKPDKNDYTQIKDGKDIDIHQIKIGVRIGKGNYGEVYLGTWR------GSQVAVKKLPA 405 Query 935 -DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993 + + +EI++++ L H ++I++ G C + + + EY+P GSL L Sbjct 406 HNINENILKEFHREINLMKNLRHPNVIQFLGSCLIPPD--ICICTEYMPRGSLYSILHDQ 463 Query 994 SIG--LAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 ++ + L+ +G+ YLH +HRDL + N+L+D + VK+ DFGL+ Sbjct 464 ALQLQWSLLIKMMIDAAKGVIYLHNSTPVILHRDLKSHNLLVDENWKVKVADFGLSTIEQ 523 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKF 1108 +G W +PE L+ ++ +DV+SFG+ L+E T D PP + Sbjct 524 QG-----ATMTACGTPCWTSPEVLRSQRYTEKADVYSFGIILWECATRQDPYFGIPPFQV 578 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 + +G G R P P P + L+ +C S RPT E + Sbjct 579 IFAVG---------------REGMRPPVPQNGPPKYIQLLIDCLNENPSHRPTMEQCLER 623 Query 1169 LKTV 1172 L+++ Sbjct 624 LESI 627 Score = 229 bits (584), Expect = 1e-62, Method: Composition-based stats. Identities = 67/356 (19%), Positives = 118/356 (33%), Gaps = 55/356 (15%) Query 537 LLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLG 596 L CF L R N G + +D +I +G Sbjct 332 GLLIIGGCFLLIR----------NRYRSSGYYKPDKNDYTQIKDGKDIDIHQIKIGVRIG 381 Query 597 QGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL--DPSHHDIALA 654 +G VY G R +V +K L + +I Sbjct 382 KGNYGEVYLGTWRGS--------------------------QVAVKKLPAHNINENILKE 415 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F+ +LM + H ++ G C+ P+ + TEY+ G L L + + + + + Sbjct 416 FHREINLMKNLRHPNVIQFLGSCLIPPDICICTEYMPRGSLYSILHDQALQLQWSLLIKM 475 Query 715 AQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--GALSRE 770 A + YL N ++H ++ N+L+ + +K++D G+ + Sbjct 476 MIDAAKGVIYLHNSTPVILHRDLKSHNLLVDE-------NWKVKVADFGLSTIEQQGATM 528 Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR- 829 W +PE L + + D + FG L E C + P P + R Sbjct 529 TACGTPCWTSPEVLR--SQRYTEKADVYSFGIILWE-CATRQDPYFGIPPFQVIFAVGRE 585 Query 830 --QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 + +P+ P+ L CL P+ RP+ L L + +D+ V Sbjct 586 GMRPPVPQNGPPKYIQLLIDCLNENPSHRPTMEQCLERLESIDSSGYSDLQYVRQQ 641 >sp|P43293|PBL11_ARATH Probable serine/threonine-protein kinase PBL11 OS=Arabidopsis thaliana OX=3702 GN=PBL11 PE=1 SV=2 Length=389 Score = 261 bits (666), Expect = 2e-76, Method: Composition-based stats. Identities = 86/329 (26%), Positives = 143/329 (43%), Gaps = 18/329 (5%) Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD-----PTN 920 + + + N + + R + +GEG FG V D P+ Sbjct 37 FSYMPRTEGEILQNANLKNFSLSELKSATRNFRPDSVVGEGGFGCVFKGWIDESSLAPSK 96 Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 GTG ++AVK L + HR W EI+ L L H +++K G C ++ + LV E+ Sbjct 97 PGTGIVIAVKRLNQEGFQGHRE-WLAEINYLGQLDHPNLVKLIGYCLEEEHR--LLVYEF 153 Query 981 VPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDN 1033 + GSL ++L R + + A G+A+LH I+RD A N+LLD+ Sbjct 154 MTRGSLENHLFRRGTFYQPLSWNTRVRMALGAARGLAFLHNAQPQVIYRDFKASNILLDS 213 Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 + K+ DFGLA+ P G + V + APE L SDV+SFGV L E Sbjct 214 NYNAKLSDFGLARDGPMGDNSH-VSTRVMGTQGYAAPEYLATGHLSVKSDVYSFGVVLLE 272 Query 1094 LLTHCDS-SQSPPTKFLELIGIAQGQMTV-LRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 LL+ + ++ P L+ A+ +T RL +++ + ++ L +C Sbjct 273 LLSGRRAIDKNQPVGEHNLVDWARPYLTNKRRLLRVMDPRLQGQYSLTRALKIAVLALDC 332 Query 1152 WETEASFRPTFENLIPILKTVHEKYQGQA 1180 +A RPT ++ ++ +H + + Sbjct 333 ISIDAKSRPTMNEIVKTMEELHIQKEASK 361 Score = 235 bits (600), Expect = 3e-67, Method: Composition-based stats. Identities = 70/367 (19%), Positives = 128/367 (35%), Gaps = 55/367 (15%) Query 565 RGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 R + NL S + + S +G+G V++G + Sbjct 42 RTEGEILQNANLKNFSLSELKSATRNFRPDSVVGEGGFGCVFKGWI-------------- 87 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 DE L P + G + + +K L+ + + + Q+ H +L + G C+ Sbjct 88 DESSLAPSKP-GTGIVIAVKRLNQEGFQGHREWLAEINYLGQLDHPNLVKLIGYCLEEEH 146 Query 683 NIMVTEYVEHGPLDVWLRRERG---HVPMAWKMVVAQQLASALSYLEN--KNLVHGNVCG 737 ++V E++ G L+ L R + ++ +A A L++L N +++ + Sbjct 147 RLLVYEFMTRGSLENHLFRRGTFYQPLSWNTRVRMALGAARGLAFLHNAQPQVIYRDFKA 206 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSL 791 NILL ++ KLSD G+ + + + APE L G L Sbjct 207 SNILLD-------SNYNAKLSDFGLARDGPMGDNSHVSTRVMGTQGYAAPEYLATG--HL 257 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ------RQHRLPEPSCPQL---- 841 S D + FG LLE+ A +++ E + RL P+L Sbjct 258 SVKSDVYSFGVVLLELLSGRRAIDKNQPVGEHNLVDWARPYLTNKRRLLRVMDPRLQGQY 317 Query 842 --------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFH 893 A L C++ + RP+ I++ + L A NP + Sbjct 318 SLTRALKIAVLALDCISIDAKSRPTMNEIVKTMEELHIQKEASKEQQNPQISIDNIINKS 377 Query 894 KRYLKKI 900 + + Sbjct 378 PQAVNYP 384 >sp|O09127|EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus musculus OX=10090 GN=Epha8 PE=1 SV=2 Length=1004 Score = 276 bits (707), Expect = 2e-76, Method: Composition-based stats. Identities = 93/316 (29%), Positives = 141/316 (45%), Gaps = 20/316 (6%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 + S + + +G G G+V VA+KALKA Sbjct 612 PHTYEEPGRAGRSFTREIEASRIHIEKIIGSGESGEVCYGRLQVPGQRD-VPVAIKALKA 670 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994 + R + E I+ H +II+ +G + +V EY+ GSL +L H Sbjct 671 GYTERQRQDFLSEAAIMGQFDHPNIIRLEGVVTRG--RLAMIVTEYMENGSLDAFLRTHD 728 Query 995 --IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 + QL+ + + GM YL YIHRDLAARNVL+D + K+ DFGL++A+ + Sbjct 729 GQFTIVQLVGMLRGVGAGMRYLSDLGYIHRDLAARNVLVDGRLVCKVSDFGLSRALEDDP 788 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 E G P+ W APE + F ASDVWSFGV ++E+L + + Sbjct 789 EAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGER------------ 836 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 MT + +E G RLP P CP ++ LM +CW + + RP F +++ +L + Sbjct 837 --PYWNMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFAHVVSVLDAL 894 Query 1173 -HEKYQGQAPSVFSVC 1187 H +A + S C Sbjct 895 VHSPESLRATATVSRC 910 Score = 256 bits (655), Expect = 2e-69, Method: Composition-based stats. Identities = 77/339 (23%), Positives = 129/339 (38%), Gaps = 46/339 (14%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 ++ I +G G V GRL+V G +++ V Sbjct 626 TREIEASRIHIEKIIGSGESGEVCYGRLQVPGQ---------------------RDVPVA 664 Query 641 LKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +K L + + F A++M Q H ++ + GV RG ++VTEY+E+G LD +L Sbjct 665 IKALKAGYTERQRQDFLSEAAIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDAFL 724 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R G + + + + + + + YL + +H ++ RN+L+ K+SD Sbjct 725 RTHDGQFTIVQLVGMLRGVGAGMRYLSDLGYIHRDLAARNVLVD-------GRLVCKVSD 777 Query 760 PGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 G+ E I W APE + + S+A D W FG + E+ GE Sbjct 778 FGLSRALEDDPEAAYTTAGGKIPIRWTAPEAIA--FRTFSSASDVWSFGVVMWEVLAYGE 835 Query 813 APLQSRSPSEKEHFYQRQHRLP-EPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P + + + + +RLP CP+ L L C + QRP F ++ L L Sbjct 836 RPYWNMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFAHVVSVLDALV 895 Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 + T + + DL G G Sbjct 896 HSPESLRATATVSRCPPP------AFARSCFDLRAGGSG 928 >sp|P41243|MATK_RAT Megakaryocyte-associated tyrosine-protein kinase OS=Rattus norvegicus OX=10116 GN=Matk PE=2 SV=1 Length=467 Score = 263 bits (673), Expect = 2e-76, Method: Composition-based stats. Identities = 102/423 (24%), Positives = 171/423 (40%), Gaps = 71/423 (17%) Query 446 SIRDGIHGPLLEPFVQAKLRP-EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 S+ HG + +L+P EDGL+L+ S HP +L V+ Sbjct 77 SLMPWFHGKISGQEAIQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVI---------H 127 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + + +DG ++ F ++ ++ G C L + Q +++ + Sbjct 128 YRVLHRDGHLTID-EAVCFCNLMDMVEHYTRDK---GAICTKLVKPKRKQGAKSAEEELA 183 Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 + +D + +T + +G+G V +G + Sbjct 184 KAG--------------WLLDLQHLTLGAQIGEGEFGAVLQGEYLGQ------------- 216 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 +V +K + A AF + ++M+++ H +L + GV + Sbjct 217 -------------KVAVKNIKCDVT--AQAFLDETAVMTKLQHRNLVRLLGVILHHG-LY 260 Query 685 MVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 +V E+V G L +LR R R V + + A +A + YLE+K LVH ++ RNIL++ Sbjct 261 IVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVS 320 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFG 801 +A K+SD G+ L + R+P W APE L G S+ D W FG Sbjct 321 EDLVA-------KVSDFGLAKAELRKGLDSSRLPVKWTAPEALKNG--RFSSKSDVWSFG 371 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSF 859 L E+ G AP S E ++ +R+ P SCP + TL C EP++RP F Sbjct 372 VLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPDSCPGPVHTLMGSCWEAEPSRRPPF 431 Query 860 RTI 862 R I Sbjct 432 RKI 434 Score = 263 bits (672), Expect = 3e-76, Method: Composition-based stats. Identities = 106/355 (30%), Positives = 160/355 (45%), Gaps = 45/355 (13%) Query 821 SEKEHFY--QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + H+ R L L R T+L Sbjct 123 RDVIHYRVLHRDGHLTIDEAVCFCNLMDM-------VEHYTRDKGAICTKLVKPKRKQGA 175 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 + A + ++L +GEG FG V Y G+ VAVK +K D Sbjct 176 KSAEEELAKAGWLLDLQHLTLGAQIGEGEFGAVLQGEYL------GQKVAVKNIKCDVTA 229 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---I 995 Q + E ++ L H ++++ G G L +VME+V G+L ++L + Sbjct 230 Q---AFLDETAVMTKLQHRNLVRLLGVILHHG---LYIVMEHVSKGNLVNFLRTRGRALV 283 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK-AVPEGHEY 1054 +QLL FA + EGM YL ++ +HRDLAARN+L+ D + K+ DFGLAK + +G + Sbjct 284 STSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAELRKGLDS 343 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 R+ PV W APE LK +F SDVWSFGV L+E+ ++ + Sbjct 344 SRL------PVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRA-------------- 383 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 +M++ ++E +E+G R+ PD CP V+ LM +CWE E S RP F ++ L Sbjct 384 PYPKMSLKEVSEAVEKGYRMEPPDSCPGPVHTLMGSCWEAEPSRRPPFRKIVEKL 438 >sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens OX=9606 GN=EPHB4 PE=1 SV=2 Length=987 Score = 276 bits (706), Expect = 3e-76, Method: Composition-based stats. Identities = 76/274 (28%), Positives = 129/274 (47%), Gaps = 21/274 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG+V VA+K LK + R + E I+ H +II+ Sbjct 621 IGAGEFGEVCRGRLKAPGKKES-CVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRL 679 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 +G + ++ E++ G+L +L + QL+ + I GM YL Y+ Sbjct 680 EGVVT--NSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGMRYLAEMSYV 737 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEYKF 1078 HRDLAARN+L++++ + K+ DFGL++ + E Y G P+ W APE + KF Sbjct 738 HRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRKF 797 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 ASD WS+G+ ++E+++ + M+ + +E+ RLP P Sbjct 798 TSASDAWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIEQDYRLPPPP 843 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 CP ++ LM +CW+ + + RP F ++ L + Sbjct 844 DCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKM 877 Score = 262 bits (669), Expect = 2e-71, Method: Composition-based stats. Identities = 77/362 (21%), Positives = 136/362 (38%), Gaps = 60/362 (17%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G V GRL+ G +E V + Sbjct 608 KEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGK---------------------KESCVAI 646 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV +++TE++E+G LD +LR Sbjct 647 KTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLR 706 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G + + + + +AS + YL + VH ++ RNIL+ ++ K+SD Sbjct 707 LNDGQFTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVN-------SNLVCKVSDF 759 Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ +IP W APE + ++A D W +G + E+ G Sbjct 760 GLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIA--FRKFTSASDAWSYGIVMWEVMSFG 817 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P S + + ++ +RLP P L L C + RP F ++ L ++ Sbjct 818 ERPYWDMSNQDVINAIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKM 877 Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 + + + + AS P + ++ FG V + A+ Sbjct 878 IRNPASLKIVARENGGASHPLLDQRQPHYS-------AFGSVGEWLR-----------AI 919 Query 930 KA 931 K Sbjct 920 KM 921 >sp|Q07498|EPHB3_CHICK Ephrin type-B receptor 3 (Fragment) OS=Gallus gallus OX=9031 GN=EPHB3 PE=2 SV=1 Length=988 Score = 276 bits (706), Expect = 3e-76, Method: Composition-based stats. Identities = 78/309 (25%), Positives = 140/309 (45%), Gaps = 23/309 (7%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-V 927 ++ + ++ +K +G G FG+V G E+ V Sbjct 595 MKVYIDPFTYEDPNEAVREFAKEIDISCVKIEEVIGAGEFGEVCRGRLK--LPGRREIFV 652 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK + R + E I+ H +II +G + + ++ E++ +L Sbjct 653 AIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIHLEGVVTKS--RPVMIITEFMENCALD 710 Query 988 DYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L + QL+ + I GM YL +Y+HRDLAARN+L++++ + K+ DFGL+ Sbjct 711 SFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLS 770 Query 1046 KAVPEG--HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 + + + Y G P+ W APE + KF ASDVWS+G+ ++E++++ + Sbjct 771 RFLEDDPADPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGER--- 827 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163 M+ + +E+ RLP P CP ++ LM +CW + + RP F Sbjct 828 -----------PYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFA 876 Query 1164 NLIPILKTV 1172 ++ L + Sbjct 877 QIVNTLDKL 885 Score = 260 bits (664), Expect = 9e-71, Method: Composition-based stats. Identities = 76/348 (22%), Positives = 134/348 (39%), Gaps = 42/348 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G V GRL++ G +E+ V + Sbjct 616 KEIDISCVKIEEVIGAGEFGEVCRGRLKLPGR---------------------REIFVAI 654 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + F AS+M Q H ++ + GV + +++TE++E+ LD +LR Sbjct 655 KTLKVGYTERQRRDFLSEASIMGQFDHPNIIHLEGVVTKSRPVMIITEFMENCALDSFLR 714 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G + + + + +A+ + YL N VH ++ RNIL+ ++ K+SD Sbjct 715 LNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVN-------SNLVCKVSDF 767 Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ +IP W APE + ++A D W +G + E+ G Sbjct 768 GLSRFLEDDPADPTYTSSLGGKIPIRWTAPEAIA--YRKFTSASDVWSYGIVMWEVMSYG 825 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P S + + ++ +RLP P CP L L C + RP F I+ L +L Sbjct 826 ERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFAQIVNTLDKL 885 Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917 + + + + S S P + + + Y Sbjct 886 IRNAASLKVIASVQSGVSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYK 933 >sp|Q55GU0|Y9955_DICDI Probable serine/threonine-protein kinase DDB_G0267514 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0267514 PE=3 SV=1 Length=916 Score = 275 bits (702), Expect = 4e-76, Method: Composition-based stats. Identities = 90/321 (28%), Positives = 139/321 (43%), Gaps = 30/321 (9%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915 + + ++ + V + LK LGEG FG V Sbjct 621 NNHSPNQYNNQGNILKNSGSVVEPPSQQQQYFSDIEISFSELKISSKLGEGTFGVVYKGL 680 Query 916 YDPTNDGTGEMVAVKALK--ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 + G VA+K +K D Q +++E+ IL L H +I+ C + Sbjct 681 WR------GSSVAIKQIKINEDVNNQVLEEFRKELTILSRLRHPNIVLLMAACT--APPN 732 Query 974 LQLVMEYVPLGSLRDYLPRHSIGLAQLL--LFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031 L + EY+P GSL D L I + L A QI +GM YLH IHRD+ + N+LL Sbjct 733 LCFITEYLPGGSLYDALHSKKIKMNMQLYKKLAIQIAQGMNYLHLSGVIHRDIKSLNLLL 792 Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091 D VKI DFGL+K + E + + SP+ W +PE L + DV++FG+ L Sbjct 793 DEHMNVKICDFGLSKLKSKSTE---MTKSIGSPI-WMSPELLMGEDYTEKVDVYAFGIIL 848 Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 +EL T P L+ + +A T + R P P+ P ++ HL++ C Sbjct 849 WELGTG-----ELPYSGLDSVQLALAVTT---------KSLRPPIPNAWPYQLSHLIQAC 894 Query 1152 WETEASFRPTFENLIPILKTV 1172 W + RP+F ++ +L + Sbjct 895 WHQDPLKRPSFTEILNLLNEI 915 Score = 254 bits (649), Expect = 4e-69, Method: Composition-based stats. Identities = 69/328 (21%), Positives = 123/328 (38%), Gaps = 45/328 (14%) Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 Q N++ G+ P + S + E+ S LG+GT VY+G R Sbjct 625 PNQYNNQGNILKNSGSVVEPPSQQQQYFSDIEISFSELKISSKLGEGTFGVVYKGLWRGS 684 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETASLMSQVSHT 668 V +K + + ++ + F + +++S++ H Sbjct 685 S--------------------------VAIKQIKINEDVNNQVLEEFRKELTILSRLRHP 718 Query 669 HLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK 728 ++ + C P +TEY+ G L L ++ + M +A Q+A ++YL Sbjct 719 NIVLLMAACTAPPNLCFITEYLPGGSLYDALHSKKIKMNMQLYKKLAIQIAQGMNYLHLS 778 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---WLAPECLP 785 ++H ++ N+LL +K+ D G+ E + I W++PE L Sbjct 779 GVIHRDIKSLNLLLDE-------HMNVKICDFGLSKLKSKSTEMTKSIGSPIWMSPELLM 831 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---QHRLPEPSCPQLA 842 G + +D + FG L E+ GE P + + +P QL+ Sbjct 832 G--EDYTEKVDVYAFGIILWELG-TGELPYSGLDSVQLALAVTTKSLRPPIPNAWPYQLS 888 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 L C +P +RPSF IL L + Sbjct 889 HLIQACWHQDPLKRPSFTEILNLLNEIP 916 >sp|G5ECJ6|CSK1_CAEEL Tyrosine-protein kinase csk-1 OS=Caenorhabditis elegans OX=6239 GN=csk-1 PE=1 SV=1 Length=539 Score = 265 bits (677), Expect = 4e-76, Method: Composition-based stats. Identities = 86/276 (31%), Positives = 135/276 (49%), Gaps = 29/276 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V L Y VA+K G E + L H +++ Sbjct 288 TIGHGEFGDVRLGTYK------NRKVALKV-SKRHGNGMLDSLLDEAKFMVGLSHPNLVT 340 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQH 1018 G D + ++ ++ EY+ G+L D L RH++ QL++FA IC+GM YL ++ Sbjct 341 LVGVVLD--DVNVYMITEYMANGNLIDLLRSRGRHALERRQLMMFAMDICQGMCYLESKQ 398 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRDLAARNVLLD+D + K+ DFGLAK + + G P+ W APE L+ +F Sbjct 399 IVHRDLAARNVLLDDDLVAKVSDFGLAK---KANSQSHDSASGKFPIKWTAPEALRHSQF 455 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SDVWSFG+ L+E+ + + ++ + + +E+G R+ P+ Sbjct 456 TTKSDVWSFGILLWEIFSFGR--------------VPYPRIPIQDVVRYIEKGYRMEAPE 501 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 CP E++ +M W A RP+F ++ L T+ Sbjct 502 GCPPEIFKVMNETWALSAQDRPSFGQVLQRLTTIRN 537 Score = 256 bits (654), Expect = 6e-73, Method: Composition-based stats. Identities = 94/438 (21%), Positives = 163/438 (37%), Gaps = 59/438 (13%) Query 446 SIRDGIHGPLLEPFVQAKLR-PEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRK 504 + + H + + LR DG +L+ ST+ P L ++ ++ Sbjct 147 NHQPWFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSF---------HGKVEH 197 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + IEQ G + F ++ +L + + A C L + + S+ Sbjct 198 YRIEQTSGGQLTCDKEEYFSNLTQLVSHYKRD---ADGLCHRLVTPIICETATFSSNGSS 254 Query 565 RGARASPRTLNLSQLSFHR----VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620 +S L F + +I +G G +V G + Sbjct 255 SFGSSSTVDLEDRTSVFRHAGLVISSNDIDVGDTIGHGEFGDVRLGTYKNR--------- 305 Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680 +V LKV + + + + A M +SH +L + GV + Sbjct 306 -----------------KVALKVSKRHGNGMLDSLLDEAKFMVGLSHPNLVTLVGVVLDD 348 Query 681 PENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRN 739 M+TEY+ +G L LR H + M+ A + + YLE+K +VH ++ RN Sbjct 349 VNVYMITEYMANGNLIDLLRSRGRHALERRQLMMFAMDICQGMCYLESKQIVHRDLAARN 408 Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER----IPWLAPECLPGGANSLSTAM 795 +LL +A K+SD G+ A S+ I W APE L + +T Sbjct 409 VLLDDDLVA-------KVSDFGLAKKANSQSHDSASGKFPIKWTAPEALRH--SQFTTKS 459 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEP 853 D W FG L EI G P + + ++ +R+ PE P++ + ++ Sbjct 460 DVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSA 519 Query 854 TQRPSFRTILRDLTRLQP 871 RPSF +L+ LT ++ Sbjct 520 QDRPSFGQVLQRLTTIRN 537 >sp|Q9SFT7|PBL26_ARATH Probable serine/threonine-protein kinase PBL26 OS=Arabidopsis thaliana OX=3702 GN=PBL26 PE=2 SV=1 Length=414 Score = 261 bits (666), Expect = 4e-76, Method: Composition-based stats. Identities = 86/284 (30%), Positives = 131/284 (46%), Gaps = 18/284 (6%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 ++ +GEG FG+V Y + TG +VAVK L + G Q + E+ +L L+ Sbjct 78 NFRQECLIGEGGFGRV----YKGKLEKTGMIVAVKQLDRN-GLQGNKEFIVEVLMLSLLH 132 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEG 1010 H+H++ G C D ++ LV EY+ GSL D+L + + + A G Sbjct 133 HKHLVNLIGYCADGDQR--LLVYEYMSRGSLEDHLLDLTPDQIPLDWDTRIRIALGAAMG 190 Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH + I+RDL A N+LLD + K+ DFGLAK P G + + V + Sbjct 191 LEYLHDKANPPVIYRDLKAANILLDGEFNAKLSDFGLAKLGPVGDKQH-VSSRVMGTYGY 249 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQ-MTVLRLT 1125 APE + + SDV+SFGV L EL+T + P L+ AQ R Sbjct 250 CAPEYQRTGQLTTKSDVYSFGVVLLELITGRRVIDTTRPKDEQNLVTWAQPVFKEPSRFP 309 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 EL + P+K + + C + EA+ RP +++ L Sbjct 310 ELADPSLEGVFPEKALNQAVAVAAMCLQEEATVRPLMSDVVTAL 353 Score = 238 bits (606), Expect = 7e-68, Method: Composition-based stats. Identities = 81/375 (22%), Positives = 130/375 (35%), Gaps = 66/375 (18%) Query 546 SLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNV 603 + P+ N + + SF + K Q +G+G V Sbjct 35 NKTHPENPKTVNEQNK-NNDEDKEVTNNIAAQTFSFRELATATKNFRQECLIGEGGFGRV 93 Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663 Y+G+L G + V +K LD + F ++S Sbjct 94 YKGKLEKTG------------------------MIVAVKQLDRNGLQGNKEFIVEVLMLS 129 Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KMVVAQQLAS 720 + H HL + G C G + ++V EY+ G L+ L +P+ W ++ +A A Sbjct 130 LLHHKHLVNLIGYCADGDQRLLVYEYMSRGSLEDHLLDLTPDQIPLDWDTRIRIALGAAM 189 Query 721 ALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERV--- 773 L YL +K +++ ++ NILL KLSD G+ LG + ++ V Sbjct 190 GLEYLHDKANPPVIYRDLKAANILLD-------GEFNAKLSDFGLAKLGPVGDKQHVSSR 242 Query 774 --ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 + APE G L+T D + FG LLE+ +R E+ Q Sbjct 243 VMGTYGYCAPEYQRTG--QLTTKSDVYSFGVVLLELITGRRVIDTTRPKDEQNLVTWAQP 300 Query 832 ------RLPEPSCPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 R PE + P L + + CL E T RP ++ L L Sbjct 301 VFKEPSRFPELADPSLEGVFPEKALNQAVAVAAMCLQEEATVRPLMSDVVTALGFLGTAP 360 Query 874 LADVLTVNPDSPASD 888 + + D P Sbjct 361 DGSISVPHYDDPPQP 375 >sp|Q8RWL6|STY17_ARATH Serine/threonine-protein kinase STY17 OS=Arabidopsis thaliana OX=3702 GN=STY17 PE=1 SV=1 Length=570 Score = 266 bits (679), Expect = 5e-76, Method: Composition-based stats. Identities = 78/304 (26%), Positives = 144/304 (47%), Gaps = 29/304 (10%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CG 937 V + +D + LK + + G +G++ Y + VA+K LK + Sbjct 274 CVEIPTDGTDEWEIDMKQLKIEKKVACGSYGELFRGTY------CSQEVAIKILKPERVN 327 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995 + + QE+ I+R + H++++++ G C +L +V E++ GS+ D+L +H Sbjct 328 AEMLREFSQEVYIMRKVRHKNVVQFIGACTRS--PNLCIVTEFMTRGSIYDFLHKHKGVF 385 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + LL A + +GM YLH + IHRDL N+L+D +VK+ DFG+A+ E Sbjct 386 KIQSLLKVALDVSKGMNYLHQNNIIHRDLKTANLLMDEHEVVKVADFGVARVQTESG--- 442 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 V W APE ++ + + +DV+S+ + L+ELLT P +L + A Sbjct 443 -VMTAETGTYRWMAPEVIEHKPYDHRADVFSYAIVLWELLTG-----ELPYSYLTPLQAA 496 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 G ++++G R P + ++ L++ CW+ + + RP F +I +L + + Sbjct 497 VG---------VVQKGLRPKIPKETHPKLTELLEKCWQQDPALRPNFAEIIEMLNQLIRE 547 Query 1176 YQGQ 1179 Sbjct 548 VGDD 551 Score = 233 bits (593), Expect = 2e-64, Method: Composition-based stats. Identities = 58/314 (18%), Positives = 117/314 (37%), Gaps = 44/314 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D K++ + G+ ++ G + V + Sbjct 285 WEIDMKQLKIEKKVACGSYGELFRGTYCSQ--------------------------EVAI 318 Query 642 KVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 K+L P + ++ F + +M +V H ++ G C R P +VTE++ G + +L Sbjct 319 KILKPERVNAEMLREFSQEVYIMRKVRHKNVVQFIGACTRSPNLCIVTEFMTRGSIYDFL 378 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + +G + + VA ++ ++YL N++H ++ N+L+ +K++D Sbjct 379 HKHKGVFKIQSLLKVALDVSKGMNYLHQNNIIHRDLKTANLLMDE-------HEVVKVAD 431 Query 760 PGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 GV W+APE + D + + L E+ GE P Sbjct 432 FGVARVQTESGVMTAETGTYRWMAPEVIEH--KPYDHRADVFSYAIVLWELL-TGELPYS 488 Query 817 SRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 +P + + ++P+ + P+L L +C +P RP+F I+ L +L Sbjct 489 YLTPLQAAVGVVQKGLRPKIPKETHPKLTELLEKCWQQDPALRPNFAEIIEMLNQLIREV 548 Query 874 LADVLTVNPDSPAS 887 D + Sbjct 549 GDDERHKDKHGGYF 562 >sp|Q9SRH7|PBL35_ARATH Serine/threonine-protein kinase PBL35 OS=Arabidopsis thaliana OX=3702 GN=PBL35 PE=1 SV=1 Length=490 Score = 263 bits (673), Expect = 5e-76, Method: Composition-based stats. Identities = 89/332 (27%), Positives = 140/332 (42%), Gaps = 16/332 (5%) Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVS 912 P + + + + + + R + LGEG FG V Sbjct 92 PVSSTTTTSNAESSLSTPIISEELNIYSHLKKFSFIDLKLATRNFRPESLLGEGGFGCVF 151 Query 913 LYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 + P GTG VAVK L D G Q W EI+ L L H +++K G C Sbjct 152 KGWVEENGTAPVKPGTGLTVAVKTLNPD-GLQGHKEWLAEINYLGNLLHPNLVKLVGYCI 210 Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLLFAQQICEGMAYLHA---QHYIHR 1022 + ++ LV E++P GSL ++L R S+ + + A +G+++LH + I+R Sbjct 211 EDDQR--LLVYEFMPRGSLENHLFRRSLPLPWSIRMKIALGAAKGLSFLHEEALKPVIYR 268 Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082 D N+LLD + K+ DFGLAK P+ + + V + APE + S Sbjct 269 DFKTSNILLDGEYNAKLSDFGLAKDAPDEGKTH-VSTRVMGTYGYAAPEYVMTGHLTSKS 327 Query 1083 DVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQ-MTVLRLTELLERGERLPRPDKC 1140 DV+SFGV L E+LT S ++ P L+ A+ + R LL+ K Sbjct 328 DVYSFGVVLLEMLTGRRSMDKNRPNGEHNLVEWARPHLLDKRRFYRLLDPRLEGHFSVKG 387 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +V L C ++ RP ++ +LK + Sbjct 388 AQKVTQLAAQCLSRDSKIRPKMSEVVEVLKPL 419 Score = 250 bits (638), Expect = 3e-71, Method: Composition-based stats. Identities = 66/341 (19%), Positives = 123/341 (36%), Gaps = 53/341 (16%) Query 575 NLSQLSFH--RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 +L + SF ++ + S LG+G V++G + G+ + Sbjct 120 HLKKFSFIDLKLATRNFRPESLLGEGGFGCVFKGWVEENGTAPVKP-------------- 165 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 G L V +K L+P + + + + H +L + G C+ + ++V E++ Sbjct 166 -GTGLTVAVKTLNPDGLQGHKEWLAEINYLGNLLHPNLVKLVGYCIEDDQRLLVYEFMPR 224 Query 693 GPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAE 749 G L+ L R +P + +M +A A LS+L K +++ + NILL Sbjct 225 GSLENHLFRRSLPLPWSIRMKIALGAAKGLSFLHEEALKPVIYRDFKTSNILLD------ 278 Query 750 GTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 KLSD G+ A + + APE + G L++ D + FG Sbjct 279 -GEYNAKLSDFGLAKDAPDEGKTHVSTRVMGTYGYAAPEYVMTG--HLTSKSDVYSFGVV 335 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS------------------CPQLATLT 845 LLE+ + ++R E + L + ++ L Sbjct 336 LLEMLTGRRSMDKNRPNGEHNLVEWARPHLLDKRRFYRLLDPRLEGHFSVKGAQKVTQLA 395 Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 +QCL+ + RP ++ L L + + Sbjct 396 AQCLSRDSKIRPKMSEVVEVLKPLPHLKDMASASYYFQTMQ 436 >sp|Q62413|EPHA6_MOUSE Ephrin type-A receptor 6 OS=Mus musculus OX=10090 GN=Epha6 PE=1 SV=2 Length=1035 Score = 276 bits (706), Expect = 5e-76, Method: Composition-based stats. Identities = 84/352 (24%), Positives = 147/352 (42%), Gaps = 57/352 (16%) Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922 ++ + D + ++ R +G G FG+V T Sbjct 596 HLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLK-TPGK 654 Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE----------- 971 VA+K LK + R + +E I+ H +II+ +G + Sbjct 655 REIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPS 714 Query 972 -----------------------------KSLQLVMEYVPLGSLRDYLPRHS--IGLAQL 1000 + + +V+EY+ GSL +L +H + QL Sbjct 715 FLRAGFLNGIQAPHPVTAGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQL 774 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 + + I GM YL Y+HRDLAARN+L++++ + K+ DFGL++ + + E Sbjct 775 VGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTG 834 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 G P+ W APE + KF ASD WS+G+ ++E++++ + +M+ Sbjct 835 GKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYGER--------------PYWEMS 880 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + +E G RLP P CP ++ LM +CW+ E + RP F +++ L + Sbjct 881 NQDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFLDKL 932 Score = 260 bits (665), Expect = 1e-70, Method: Composition-based stats. Identities = 87/404 (22%), Positives = 135/404 (33%), Gaps = 88/404 (22%) Query 570 SPRTLNLSQLSFHR----VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 P T L+ H +D I +G G V GRL+ G Sbjct 607 DPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGK------------ 654 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVR----- 679 +E+ V +K L H D F AS+M Q H ++ + GV + Sbjct 655 ---------REIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPA 705 Query 680 -------------------------------------GPENIMVTEYVEHGPLDVWLRRE 702 G ++V EY+E+G LD +LR+ Sbjct 706 IGVEAFCPSFLRAGFLNGIQAPHPVTAGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKH 765 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 GH + + + + +AS + YL + VH ++ RNIL+ ++ K+SD G+ Sbjct 766 DGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVN-------SNLVCKVSDFGL 818 Query 763 GL-------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 A + I W APE + S+A D W +G + E+ GE P Sbjct 819 SRVLEDDPEAAYTTTGGKIPIRWTAPEAIA--YRKFSSASDAWSYGIVMWEVMSYGERPY 876 Query 816 QSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 S + + +RL P P L L C E RP F I+ L +L + Sbjct 877 WEMSNQDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNP 936 Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917 A V + Y + + + Y Sbjct 937 SALHTLVEDILVMPESPGDVPEYPLFVTVGDW--LDSIKMGQYK 978 >sp|Q03142|FGFR4_MOUSE Fibroblast growth factor receptor 4 OS=Mus musculus OX=10090 GN=Fgfr4 PE=1 SV=3 Length=799 Score = 271 bits (693), Expect = 9e-76, Method: Composition-based stats. Identities = 100/304 (33%), Positives = 147/304 (48%), Gaps = 38/304 (13%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE---MVAVKALKADCGPQHRSGWKQ 946 F + L + LGEG FG+V + + VAVK LK + + + Sbjct 457 WEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPSRPDQTSTVAVKMLKDNASDKDLADLVS 516 Query 947 EIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-------------- 991 E+++++ + H++II G C +G L +++E G+LR++L Sbjct 517 EMEVMKLIGRHKNIINLLGVCTQEG--PLYVIVECAAKGNLREFLRARRPPGPDLSPDGP 574 Query 992 ---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + L+ A Q+ GM YL ++ IHRDLAARNVL+ D ++KI DFGLA+ V Sbjct 575 RSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDDVMKIADFGLARGV 634 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 +YY+ +G PV W APE L + + + SDVWSF + L+E+ T Sbjct 635 HH-IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFEILLWEIFT------------ 681 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 L G + V L LL G R+ RP CP E+Y LM+ CW S RPTF+ L+ Sbjct 682 --LGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRECWHAAPSQRPTFKQLVEA 739 Query 1169 LKTV 1172 L V Sbjct 740 LDKV 743 Score = 228 bits (580), Expect = 5e-61, Method: Composition-based stats. Identities = 64/315 (20%), Positives = 111/315 (35%), Gaps = 51/315 (16%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L+L + + LG+G V + E + Sbjct 448 NLDLPLDPLWEFPRDRLVLGKPLGEGCFGQV-----------------VRAEAFGMDPSR 490 Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690 Q V +K+L + D L +M + H ++ + GVC + ++ E Sbjct 491 PDQTSTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECA 550 Query 691 EHGPLDVWLRRER---------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNV 735 G L +LR R G + + A Q+A + YLE++ +H ++ Sbjct 551 AKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDL 610 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGAN 789 RN+L+ +K++D G+ G + + + W+APE L Sbjct 611 AARNVLVTE-------DDVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRV- 662 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847 + D W F L EI G +P E + HR+ P +L L + Sbjct 663 -YTHQSDVWSFEILLWEIFTLGGSPYPGIPVEELFSLLREGHRMERPPNCPSELYGLMRE 721 Query 848 CLTYEPTQRPSFRTI 862 C P+QRP+F+ + Sbjct 722 CWHAAPSQRPTFKQL 736 >sp|Q62270|SRMS_MOUSE Tyrosine-protein kinase Srms OS=Mus musculus OX=10090 GN=Srms PE=2 SV=2 Length=496 Score = 263 bits (671), Expect = 1e-75, Method: Composition-based stats. Identities = 100/314 (32%), Positives = 141/314 (45%), Gaps = 28/314 (9%) Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926 N + D + R LGEG FG+V + + Sbjct 204 NWKLIQNPLLQPCIPQIPLVQDEWERPRSEFVLRRKLGEGFFGEVWEGLWLGS-----IP 258 Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VAVK +K + +EI+ L++L HE +I+ C + + +V E + G+L Sbjct 259 VAVKVIK--SADMKLADLTKEIEALKSLRHERLIRLHAICSLG--EPVYIVTELMGKGNL 314 Query 987 RDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 + YL ++ L LL FA Q+ EGM+YL + +HRDLAARNVL+ +D K+ DFG Sbjct 315 QVYLGSSEGKALSLPHLLGFACQVAEGMSYLEERRVVHRDLAARNVLVGDDLTCKVADFG 374 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 LA+ + + + Y PV W APE F SDVWSFG+ LYE+ T+ Sbjct 375 LARLLKD--DVYSPSSGSKIPVKWTAPEAANYRVFSQKSDVWSFGILLYEVFTYGQ---- 428 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163 MT + + RG RLPRP CP EVY LM CW+ RPTF Sbjct 429 ----------CPYEGMTNHETLQQISRGYRLPRPAVCPAEVYVLMVECWKGSPEERPTFA 478 Query 1164 NLIPILKTVHEKYQ 1177 L L ++ + Sbjct 479 ILREKLNAINRRLH 492 Score = 261 bits (666), Expect = 5e-75, Method: Composition-based stats. Identities = 92/453 (20%), Positives = 151/453 (33%), Gaps = 81/453 (18%) Query 433 YLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQ 489 YL P S + + Q L G +LI S S L+V Sbjct 110 YLAKATPEP---PSDQPWYFSGISRAQAQQLLLSPANAPGAFLIRPSESSIGGYSLSVRA 166 Query 490 RSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRR 549 +++ + I + G+ FPS+ L A + + L + Sbjct 167 QAKVC---------HYRICMAPSGSLYLQEGQLFPSLDALLAYYKTNWKLIQN---PLLQ 214 Query 550 CCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLR 609 C+PQ + + E LG+G V+EG Sbjct 215 PCIPQIPLVQDE--------------------WERPRSEFVLRRKLGEGFFGEVWEGLWL 254 Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTH 669 + V +KV+ + +A + + + H Sbjct 255 GS-------------------------IPVAVKVIKSADMKLA-DLTKEIEALKSLRHER 288 Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENK 728 L +H +C G +VTE + G L V+L G + + + A Q+A +SYLE + Sbjct 289 LIRLHAICSLGEPVYIVTELMGKGNLQVYLGSSEGKALSLPHLLGFACQVAEGMSYLEER 348 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-----EERVERIPWLAPEC 783 +VH ++ RN+L+ G K++D G+ + W APE Sbjct 349 RVVHRDLAARNVLV-------GDDLTCKVADFGLARLLKDDVYSPSSGSKIPVKWTAPEA 401 Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QL 841 S D W FG L E+ G+ P + + E R +RLP P CP ++ Sbjct 402 A--NYRVFSQKSDVWSFGILLYEVFTYGQCPYEGMTNHETLQQISRGYRLPRPAVCPAEV 459 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 L +C P +RP+F + L + Sbjct 460 YVLMVECWKGSPEERPTFAILREKLNAINRRLH 492 >sp|Q9UF33|EPHA6_HUMAN Ephrin type-A receptor 6 OS=Homo sapiens OX=9606 GN=EPHA6 PE=1 SV=3 Length=1036 Score = 275 bits (703), Expect = 1e-75, Method: Composition-based stats. Identities = 86/363 (24%), Positives = 151/363 (42%), Gaps = 57/363 (16%) Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911 E +R + ++ + D + ++ R +G G FG+V Sbjct 586 EEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEV 645 Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 T VA+K LK + R + +E I+ H +II+ +G + Sbjct 646 CSGRLK-TPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSF 704 Query 972 ----------------------------------------KSLQLVMEYVPLGSLRDYLP 991 + + +V+EY+ GSL +L Sbjct 705 PAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLR 764 Query 992 RHS--IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 +H + QL+ + I GM YL Y+HRDLAARN+L++++ + K+ DFGL++ + Sbjct 765 KHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLE 824 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 + E G P+ W APE + KF ASD WS+G+ ++E++++ + Sbjct 825 DDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMWEVMSYGER--------- 875 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 +M+ + +E G RLP P CP ++ LM +CW+ E + RP F +++ L Sbjct 876 -----PYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFL 930 Query 1170 KTV 1172 + Sbjct 931 DKL 933 Score = 259 bits (662), Expect = 3e-70, Method: Composition-based stats. Identities = 88/404 (22%), Positives = 136/404 (34%), Gaps = 88/404 (22%) Query 570 SPRTLNLSQLSFHR----VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 P T L+ H +D I +G G V GRL+ G Sbjct 608 DPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGK------------ 655 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVR----- 679 +E+ V +K L H D F AS+M Q H ++ + GV + Sbjct 656 ---------REIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPA 706 Query 680 -------------------------------------GPENIMVTEYVEHGPLDVWLRRE 702 G ++V EY+E+G LD +LR+ Sbjct 707 IGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKH 766 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 GH + + + + +AS + YL + VH ++ RNIL+ ++ K+SD G+ Sbjct 767 DGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVN-------SNLVCKVSDFGL 819 Query 763 GL-------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 A + I W APE + S+A D W +G + E+ GE P Sbjct 820 SRVLEDDPEAAYTTTGGKIPIRWTAPEAIA--YRKFSSASDAWSYGIVMWEVMSYGERPY 877 Query 816 QSRSPSEKEHFYQRQHRLP-EPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 S + + +RLP CP L L C E RP F I+ L +L + Sbjct 878 WEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNP 937 Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917 A V + Y + + + Y Sbjct 938 SALHTLVEDILVMPESPGEVPEYPLFVTVGDW--LDSIKMGQYK 979 >sp|Q91743|FGFR4_XENLA Fibroblast growth factor receptor 4 OS=Xenopus laevis OX=8355 GN=fgfr4 PE=2 SV=1 Length=828 Score = 271 bits (693), Expect = 1e-75, Method: Composition-based stats. Identities = 104/329 (32%), Positives = 153/329 (47%), Gaps = 41/329 (12%) Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM---VA 928 + + P F + L + LGEG FG+V E VA Sbjct 465 CAPMLPGVMEVELPLDAKWEFPRDRLVLGKPLGEGCFGQVVRAEGYGIEKDRPEKPVTVA 524 Query 929 VKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 VK LK + + S E+++++ + H++II G C +G L +++EY G+LR Sbjct 525 VKMLKDNGTDKDLSDLISEMELMKVIGKHKNIINLLGVCTQEG--PLFVIVEYASKGNLR 582 Query 988 DYL-----------------PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030 ++L P + L+ A Q+ GM YL ++ IHRDLAARNVL Sbjct 583 EFLRARRPPTPEDAFDITKVPEELLSFKDLVSCAYQVARGMEYLESKRCIHRDLAARNVL 642 Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 + D ++KI DFGLA+ V +YY+ +G PV W APE L + + + SD+WSFGV Sbjct 643 VAEDNVMKIADFGLARGV-HDIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDIWSFGVL 701 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 +E+ T L G + L +LL G R+ +P C E+Y LM+ Sbjct 702 TWEIFT--------------LGGSPYPVIPYEELFKLLREGHRMDKPSNCTHELYMLMRE 747 Query 1151 CWETEASFRPTFENLIP---ILKTVHEKY 1176 CW + RPTF+ L IL V E+Y Sbjct 748 CWHAVPTQRPTFKQLEHLDRILTAVSEEY 776 Score = 236 bits (602), Expect = 1e-63, Method: Composition-based stats. Identities = 75/350 (21%), Positives = 125/350 (36%), Gaps = 51/350 (15%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 + L + + + LG+G V +R EG G ++ + P P Sbjct 474 EVELPLDAKWEFPRDRLVLGKPLGEGCFGQV----VRAEGYG------IEKDRPEKP--- 520 Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690 + V +K+L + D L LM + H ++ + GVC + ++ EY Sbjct 521 ----VTVAVKMLKDNGTDKDLSDLISEMELMKVIGKHKNIINLLGVCTQEGPLFVIVEYA 576 Query 691 EHGPLDVWLRRERGHVPMAW---------------KMVVAQQLASALSYLENKNLVHGNV 735 G L +LR R P + A Q+A + YLE+K +H ++ Sbjct 577 SKGNLREFLRARRPPTPEDAFDITKVPEELLSFKDLVSCAYQVARGMEYLESKRCIHRDL 636 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGAN 789 RN+L+A + +K++D G+ G + + + W+APE L Sbjct 637 AARNVLVAEDNV-------MKIADFGLARGVHDIDYYKKTSNGRLPVKWMAPEALFDRV- 688 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQ 847 + D W FG EI G +P E + HR+ P +L L + Sbjct 689 -YTHQSDIWSFGVLTWEIFTLGGSPYPVIPYEELFKLLREGHRMDKPSNCTHELYMLMRE 747 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897 C PTQRP+F+ + L + + P S Sbjct 748 CWHAVPTQRPTFKQLEHLDRILTAVSEEYLDLSMPFEQYSPSCEDSASTC 797 >sp|Q8H186|PBL1_ARATH Probable serine/threonine-protein kinase PBL1 OS=Arabidopsis thaliana OX=3702 GN=PBL1 PE=1 SV=1 Length=389 Score = 259 bits (661), Expect = 1e-75, Method: Composition-based stats. Identities = 83/287 (29%), Positives = 132/287 (46%), Gaps = 19/287 (7%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +GEG FG V D PT +G ++AVK L D HR W EI+ L L H Sbjct 67 VGEGGFGCVFRGWLDETTLTPTKSSSGLVIAVKRLNPDGFQGHRE-WLTEINYLGQLSHP 125 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------SIGLAQLLLFAQQICEGM 1011 +++K G C + ++ LV E++ GSL ++L + + + A +G+ Sbjct 126 NLVKLIGYCLEDEQR--LLVYEFMHKGSLENHLFANGNKDFKPLSWILRIKVALDAAKGL 183 Query 1012 AYLHAQ--HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 A+LH+ I+RD+ A N+LLD+D K+ DFGLA+ P G + Y V + A Sbjct 184 AFLHSDPVKVIYRDIKASNILLDSDFNAKLSDFGLARDGPMGEQSY-VSTRVMGTFGYAA 242 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTEL 1127 PE + SDV+SFGV L ELL + + P K L+ A+ +T R + + Sbjct 243 PEYVSTGHLNARSDVYSFGVVLLELLCGRQALDHNRPAKEQNLVDWARPYLTSRRKVLLI 302 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 ++ + + + C E RPT + ++ L + + Sbjct 303 VDTRLNSQYKPEGAVRLASIAVQCLSFEPKSRPTMDQVVRALVQLQD 349 Score = 241 bits (614), Expect = 3e-69, Method: Composition-based stats. Identities = 74/337 (22%), Positives = 134/337 (40%), Gaps = 54/337 (16%) Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 G S T+ + ++ + S +G+G V+ G L D Sbjct 36 TEGEILSSTTVKSFSFNELKLATRNFRSDSVVGEGGFGCVFRGWL--------------D 81 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 E L P + L + +K L+P + + + Q+SH +L + G C+ + Sbjct 82 ETTLTPTK-SSSGLVIAVKRLNPDGFQGHREWLTEINYLGQLSHPNLVKLIGYCLEDEQR 140 Query 684 IMVTEYVEHGPLDVWLR--RERGHVPMAW--KMVVAQQLASALSYLENK--NLVHGNVCG 737 ++V E++ G L+ L + P++W ++ VA A L++L + +++ ++ Sbjct 141 LLVYEFMHKGSLENHLFANGNKDFKPLSWILRIKVALDAAKGLAFLHSDPVKVIYRDIKA 200 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPECLPGGANSL 791 NILL + KLSD G+ + + + APE + G L Sbjct 201 SNILLD-------SDFNAKLSDFGLARDGPMGEQSYVSTRVMGTFGYAAPEYVSTG--HL 251 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH--------------RLPEPS 837 + D + FG LLE+ +A +R E+ + RL Sbjct 252 NARSDVYSFGVVLLELLCGRQALDHNRPAKEQNLVDWARPYLTSRRKVLLIVDTRLNSQY 311 Query 838 CP----QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P +LA++ QCL++EP RP+ ++R L +LQ Sbjct 312 KPEGAVRLASIAVQCLSFEPKSRPTMDQVVRALVQLQ 348 >sp|O73875|EPB4A_DANRE Ephrin type-B receptor 4a OS=Danio rerio OX=7955 GN=ephb4a PE=1 SV=3 Length=987 Score = 274 bits (701), Expect = 1e-75, Method: Composition-based stats. Identities = 82/336 (24%), Positives = 142/336 (42%), Gaps = 22/336 (7%) Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 + + Q +P + ++ + ++ +K Sbjct 566 IYCIRKQNNYKDP-ELSDKNGQYLMGQGVKVYIDPFTYEDPNEAVREFAKEIDVSCVKIE 624 Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G FG+V VA+K LK + R + E I+ H +II Sbjct 625 EVIGAGEFGEVCRGRLRIPGKKEN-YVAIKTLKGGYTDKQRRDFLAEASIMGQFQHPNII 683 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQH 1018 +G + ++ E++ G+L +L QL+ + I GM YL Sbjct 684 HLEGIIT--ASCPVMILTEFMENGALDSFLRLNDGQFTPIQLVGMLRGIASGMKYLSEMS 741 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE--YYRVREDGDSPVFWYAPECLKEY 1076 Y+HRDLAARN+L++++ + K+ DFGL++ + E Y G P+ W APE + Sbjct 742 YVHRDLAARNILVNSNLVCKVSDFGLSRFLQENSSDPTYTSSLGGKIPIRWTAPEAIAFR 801 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 KF ASDVWS+G+ ++E+++ + M+ + +E+ RLP Sbjct 802 KFTCASDVWSYGIVMWEVMSFGER--------------PYWDMSNQDVINAIEQDYRLPP 847 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P CP ++ LM +CW+ E + RP F N++ L + Sbjct 848 PPDCPTYLHQLMLDCWQKERTARPRFANIVSALDKL 883 Score = 261 bits (666), Expect = 4e-71, Method: Composition-based stats. Identities = 79/337 (23%), Positives = 130/337 (39%), Gaps = 42/337 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + +G G V GRLR+ G +E V + Sbjct 614 KEIDVSCVKIEEVIGAGEFGEVCRGRLRIPGK---------------------KENYVAI 652 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + D F AS+M Q H ++ + G+ +++TE++E+G LD +LR Sbjct 653 KTLKGGYTDKQRRDFLAEASIMGQFQHPNIIHLEGIITASCPVMILTEFMENGALDSFLR 712 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G + + + +AS + YL + VH ++ RNIL+ ++ K+SD Sbjct 713 LNDGQFTPIQLVGMLRGIASGMKYLSEMSYVHRDLAARNILVN-------SNLVCKVSDF 765 Query 761 GVGL-------GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 G+ +IP W APE + + A D W +G + E+ G Sbjct 766 GLSRFLQENSSDPTYTSSLGGKIPIRWTAPEAIA--FRKFTCASDVWSYGIVMWEVMSFG 823 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 E P S + + ++ +RLP P L L C E T RP F I+ L +L Sbjct 824 ERPYWDMSNQDVINAIEQDYRLPPPPDCPTYLHQLMLDCWQKERTARPRFANIVSALDKL 883 Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + +T + S P + + L G Sbjct 884 IRNPASLKITAQEGAGPSHPLLDQRSPLTPSSCGTVG 920 >sp|P43404|ZAP70_MOUSE Tyrosine-protein kinase ZAP-70 OS=Mus musculus OX=10090 GN=Zap70 PE=1 SV=3 Length=618 Score = 266 bits (680), Expect = 1e-75, Method: Composition-based stats. Identities = 97/334 (29%), Positives = 153/334 (46%), Gaps = 22/334 (7%) Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899 ++ TL S T EP + + T + + + + + L Sbjct 281 RVDTLNSDGYTPEPARL-ASSTDKPRPMPMDTSVYESPYSDPEELKDKKLFLKRENLLVA 339 Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +LG G+FG V Y VA+K LK + +E I+ L + +I Sbjct 340 DIELGCGNFGSVRQGVYRMRKKQ--IDVAIKVLKQGTEKADKDEMMREAQIMHQLDNPYI 397 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 ++ G C+ ++L LVME G L +L + I ++ + Q+ GM YL + Sbjct 398 VRLIGVCQ---AEALMLVMEMAGGGPLHKFLLGKKEEIPVSNVAELLHQVAMGMKYLEEK 454 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +++HRDLAARNVLL N KI DFGL+KA+ YY R G P+ WYAPEC+ K Sbjct 455 NFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRK 514 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWS+GVT++E ++ +M + + +++G+R+ P Sbjct 515 FSSRSDVWSYGVTMWEAFSYGQK--------------PYKKMKGPEVLDFIKQGKRMECP 560 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +CP E+Y LM +CW + RP F + ++ Sbjct 561 PECPPEMYALMSDCWIYKWEDRPDFLTVEQRMRN 594 Score = 240 bits (612), Expect = 1e-66, Method: Composition-based stats. Identities = 92/499 (18%), Positives = 164/499 (33%), Gaps = 103/499 (21%) Query 445 MSIRDGIHGPLLEPFVQAKL---RPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLR 501 H L + KL + DG +L+ L++ + Sbjct 158 HERMPWYHSSLTREEAERKLYSGQQTDGKFLLRPR-KEQGTYALSL---------VYGKT 207 Query 502 LRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL--------- 552 + + I Q G F ++ +L L+ L+A + L+ C Sbjct 208 VYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLK---LKADGLIYRLKEVCPNSSASAAVA 264 Query 553 -----------PQPGETSNLIIMRG------------ARASPRTLNLSQLSFHRVDQKEI 589 QP + + G + P ++ S D +E+ Sbjct 265 APTLPAHPSTFTQPQRRVDTLNSDGYTPEPARLASSTDKPRPMPMDTSVYESPYSDPEEL 324 Query 590 TQLS-------------HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 LG G +V +G R R ++ Sbjct 325 KDKKLFLKRENLLVADIELGCGNFGSVRQGV----------------------YRMRKKQ 362 Query 637 LRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 + V +KVL A +M Q+ + ++ + GVC + ++V E GPL Sbjct 363 IDVAIKVLKQGTEKADKDEMMREAQIMHQLDNPYIVRLIGVC-QAEALMLVMEMAGGGPL 421 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +L ++ +P++ + Q+A + YLE KN VH ++ RN+LL + Sbjct 422 HKFLLGKKEEIPVSNVAELLHQVAMGMKYLEEKNFVHRDLAARNVLL-------VNRHYA 474 Query 756 KLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 K+SD G+ + + + W APEC+ S+ D W +G T+ E Sbjct 475 KISDFGLSKALGADDSYYTARSAGKWPLKWYAPECI--NFRKFSSRSDVWSYGVTMWEAF 532 Query 809 FDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 G+ P + E F ++ R+ P P++ L S C Y+ RP F T+ + + Sbjct 533 SYGQKPYKKMKGPEVLDFIKQGKRMECPPECPPEMYALMSDCWIYKWEDRPDFLTVEQRM 592 Query 867 TRLQPHNLADVLTVNPDSP 885 + Sbjct 593 RNYYYSLASRAEGPPQCEQ 611 >sp|P46573|PBL10_ARATH Probable serine/threonine-protein kinase PBL10 OS=Arabidopsis thaliana OX=3702 GN=PBL10 PE=1 SV=2 Length=412 Score = 259 bits (663), Expect = 1e-75, Method: Composition-based stats. Identities = 83/285 (29%), Positives = 130/285 (46%), Gaps = 18/285 (6%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LGEG FG V D + GTG ++AVK L D G Q W E++ L H Sbjct 75 LGEGGFGSVFKGWIDEQTLTASKPGTGVVIAVKKLNQD-GWQGHQEWLAEVNYLGQFSHP 133 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMA 1012 +++K G C + + LV E++P GSL ++L R + L A +G+A Sbjct 134 NLVKLIGYCLEDEHR--LLVYEFMPRGSLENHLFRRGSYFQPLSWTLRLKVALGAAKGLA 191 Query 1013 YLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 +LH I+RD N+LLD++ K+ DFGLAK P G + + V + AP Sbjct 192 FLHNAETSVIYRDFKTSNILLDSEYNAKLSDFGLAKDGPTGDKSH-VSTRIMGTYGYAAP 250 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTELL 1128 E L SDV+S+GV L E+L+ + ++ P +L+ A+ + R L ++ Sbjct 251 EYLATGHLTTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLLANKRKLFRVI 310 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + + + C+V L C E RP ++ L+ + Sbjct 311 DNRLQDQYSMEEACKVATLALRCLTFEIKLRPNMNEVVSHLEHIQ 355 Score = 243 bits (621), Expect = 7e-70, Method: Composition-based stats. Identities = 71/337 (21%), Positives = 137/337 (41%), Gaps = 55/337 (16%) Query 565 RGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 R ++ NL +F + + S LG+G +V++G + Sbjct 43 RTEGEILQSPNLKSFTFAELKAATRNFRPDSVLGEGGFGSVFKGWI-------------- 88 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 ++ + G + + +K L+ + + + Q SH +L + G C+ Sbjct 89 -DEQTLTASKPGTGVVIAVKKLNQDGWQGHQEWLAEVNYLGQFSHPNLVKLIGYCLEDEH 147 Query 683 NIMVTEYVEHGPLDVWLRRERGHV-PMAW--KMVVAQQLASALSYLEN--KNLVHGNVCG 737 ++V E++ G L+ L R + P++W ++ VA A L++L N ++++ + Sbjct 148 RLLVYEFMPRGSLENHLFRRGSYFQPLSWTLRLKVALGAAKGLAFLHNAETSVIYRDFKT 207 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSL 791 NILL + KLSD G+ + ++ + + APE L G L Sbjct 208 SNILLD-------SEYNAKLSDFGLAKDGPTGDKSHVSTRIMGTYGYAAPEYLATG--HL 258 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ--------------HRLPEPS 837 +T D + +G LLE+ A ++R P E++ + +RL + Sbjct 259 TTKSDVYSYGVVLLEVLSGRRAVDKNRPPGEQKLVEWARPLLANKRKLFRVIDNRLQDQY 318 Query 838 C----PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 ++ATL +CLT+E RP+ ++ L +Q Sbjct 319 SMEEACKVATLALRCLTFEIKLRPNMNEVVSHLEHIQ 355 >sp|Q03526|ITK_MOUSE Tyrosine-protein kinase ITK/TSK OS=Mus musculus OX=10090 GN=Itk PE=1 SV=1 Length=625 Score = 266 bits (680), Expect = 1e-75, Method: Composition-based stats. Identities = 80/425 (19%), Positives = 154/425 (36%), Gaps = 66/425 (16%) Query 449 DGIHGPLLEPFVQAKLRP--EDGLYLIHWSTSHPYRLILTVAQRSQAPDGM--QSLRLRK 504 + + + + L ++G +++ S + P ++V ++ + + +++ Sbjct 244 EWYNKSISRDKAEKLLLDTGKEGAFMVRDSRT-PGTYTVSVFTKAIISENPCIKHYHIKE 302 Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 F S+ L Q G LR + Sbjct 303 ---TNDSPKRYYVAEKYVFDSIPLLIQYHQYNG---GGLVTRLRYP------------VC 344 Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 + +P T L + + E+T + +G G V+ G + Sbjct 345 SWRQKAPVTAGLRYGKWV-IQPSELTFVQEIGSGQFGLVHLGYWLNKD------------ 391 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 +V +K + F E A +M ++SH L ++GVC+ Sbjct 392 -------------KVAIKTIQEGAMS-EEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPIC 437 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 +V E++EHG L +LR +RG + + + ++YLE ++H ++ RN L+ Sbjct 438 LVFEFMEHGCLSDYLRSQRGLFAAETLLGMCLDVCEGMAYLEKACVIHRDLAARNCLV-- 495 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWG 799 G + IK+SD G+ L + + W +PE + S+ D W Sbjct 496 -----GENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFS--FSRYSSKSDVWS 548 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857 FG + E+ +G+ P ++RS SE RL P + + + + C +P RP Sbjct 549 FGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASCHVYQIMNHCWKEKPEDRP 608 Query 858 SFRTI 862 F + Sbjct 609 PFSQL 613 Score = 258 bits (658), Expect = 1e-72, Method: Composition-based stats. Identities = 83/291 (29%), Positives = 132/291 (45%), Gaps = 27/291 (9%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 V L ++++G G FG V L + + VA+K ++ G + Sbjct 357 RYGKWVIQPSELTFVQEIGSGQFGLVHLGYWLNKDK-----VAIKTIQE--GAMSEEDFI 409 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLF 1003 +E +++ L H +++ G C +Q + LV E++ G L DYL LL Sbjct 410 EEAEVMMKLSHPKLVQLYGVCLEQA--PICLVFEFMEHGCLSDYLRSQRGLFAAETLLGM 467 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 +CEGMAYL IHRDLAARN L+ ++++K+ DFG+ + V + + Y Sbjct 468 CLDVCEGMAYLEKACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLD--DQYTSSTGTKF 525 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 PV W +PE ++ SDVWSFGV ++E+ + I + Sbjct 526 PVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGK--------------IPYENRSNSE 571 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + E + G RL +P C VY +M +CW+ + RP F L+ L + E Sbjct 572 VVEDISTGFRLYKPRLASCHVYQIMNHCWKEKPEDRPPFSQLLSQLAEIAE 622 >sp|Q9SII6|PIX13_ARATH Probable serine/threonine-protein kinase PIX13 OS=Arabidopsis thaliana OX=3702 GN=PIX13 PE=1 SV=2 Length=414 Score = 259 bits (662), Expect = 2e-75, Method: Composition-based stats. Identities = 85/283 (30%), Positives = 128/283 (45%), Gaps = 16/283 (6%) Query 903 LGEGHFGKVSLYCYD---PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LGEG FGKV + P G ++AVK L A+ Q W+ E++ L + H ++ Sbjct 93 LGEGGFGKVFKGWLEDKTPGKQSNGTVIAVKKLNAE-SFQGFEEWQCEVNFLGRVSHPNL 151 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYL 1014 +K G C + E L LV EY+ GSL ++L R + L A +G+A+L Sbjct 152 VKLLGYCLEGEE--LLLVYEYMQKGSLENHLFRKGSAVQPLSWEIRLKIAIGAAKGLAFL 209 Query 1015 H--AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 H + I+RD A N+LLD KI DFGLAK P + + + + APE Sbjct 210 HASEKQVIYRDFKASNILLDGSYNAKISDFGLAKLGPSASQSH-ITTRVMGTHGYAAPEY 268 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTELLER 1130 + Y SDV+ FGV L E+LT + + PT L + ++ R L +++ Sbjct 269 VATGHLYVKSDVYGFGVVLAEILTGLHALDPTRPTGQHNLTEWIKPHLSERRKLRSIMDP 328 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 P K V L C E RP+ + ++ L+ + Sbjct 329 RLEGKYPFKSAFRVAQLALKCLGPEPKNRPSMKEVVESLELIE 371 Score = 233 bits (593), Expect = 4e-66, Method: Composition-based stats. Identities = 76/362 (21%), Positives = 135/362 (37%), Gaps = 55/362 (15%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + L+ R + + LG+G V++G L + G G + Sbjct 71 NLRIFSLAELRASTRNFRSENVLGEGGFGKVFKGWLEDKTPGKQSNGTV----------- 119 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 + +K L+ + + + +VSH +L + G C+ G E ++V EY++ Sbjct 120 ------IAVKKLNAESFQGFEEWQCEVNFLGRVSHPNLVKLLGYCLEGEELLLVYEYMQK 173 Query 693 GPLDVWLRRERGHV-PMAW--KMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGL 747 G L+ L R+ V P++W ++ +A A L++L K +++ + NILL Sbjct 174 GSLENHLFRKGSAVQPLSWEIRLKIAIGAAKGLAFLHASEKQVIYRDFKASNILLD---- 229 Query 748 AEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 S K+SD G+ S + + APE + G L D +GFG Sbjct 230 ---GSYNAKISDFGLAKLGPSASQSHITTRVMGTHGYAAPEYVATG--HLYVKSDVYGFG 284 Query 802 ATLLEICF-----DGEAPLQSRSPSEKEHFYQRQHR-------------LPEPSCPQLAT 843 L EI D P + +E + + R P S ++A Sbjct 285 VVLAEILTGLHALDPTRPTGQHNLTEWIKPHLSERRKLRSIMDPRLEGKYPFKSAFRVAQ 344 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 L +CL EP RPS + ++ L ++ N + + S +++ Sbjct 345 LALKCLGPEPKNRPSMKEVVESLELIEAANEKPLERRTTRASPSIRQQQGHYRPQQLSSF 404 Query 904 GE 905 Sbjct 405 RP 406 >sp|Q16288|NTRK3_HUMAN NT-3 growth factor receptor OS=Homo sapiens OX=9606 GN=NTRK3 PE=1 SV=2 Length=839 Score = 271 bits (693), Expect = 2e-75, Method: Composition-based stats. Identities = 112/348 (32%), Positives = 157/348 (45%), Gaps = 48/348 (14%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914 P I + + N P + +R + R+LGEG FGKV L Sbjct 497 GPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAE 556 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 CY+ + +VAVKALK D R +++E ++L L HEHI+K+ G C D L Sbjct 557 CYNLSPTKDKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PL 613 Query 975 QLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQ 1017 +V EY+ G L +L H +GL+Q+L A QI GM YL +Q Sbjct 614 IMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQ 673 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG-------------DSP 1064 H++HRDLA RN L+ + LVKIGDFG+++ V Y G P Sbjct 674 HFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLP 733 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 + W PE + KF SDVWSFGV L+E+ T+ Q++ + Sbjct 734 IRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQ--------------PWFQLSNTEV 779 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 E + +G L RP CP EVY +M CW+ E R + + IL + Sbjct 780 IECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 827 Score = 258 bits (658), Expect = 7e-71, Method: Composition-based stats. Identities = 73/323 (23%), Positives = 126/323 (39%), Gaps = 65/323 (20%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + +++I LG+G V+ + + L P +D+ + V +K Sbjct 533 IKRRDIVLKRELGEGAFGKVF----------------LAECYNLSPTKDK---MLVAVKA 573 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702 L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR Sbjct 574 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633 Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 +G + ++ + +A Q+AS + YL +++ VH ++ RN L+ Sbjct 634 PDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV------ 687 Query 749 EGTSPFIKLSDPGVGLGALSREE--------------------RVERIPWLAPECLPGGA 788 G + +K+ D G+ S + + I W+ PE + Sbjct 688 -GANLLVKIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIM--Y 744 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTS 846 +T D W FG L EI G+ P S +E + L P ++ + Sbjct 745 RKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVML 804 Query 847 QCLTYEPTQRPSFRTILRDLTRL 869 C EP QR + + I + L L Sbjct 805 GCWQREPQQRLNIKEIYKILHAL 827 >sp|Q9C9U5|SIS8_ARATH Probable serine/threonine-protein kinase SIS8 OS=Arabidopsis thaliana OX=3702 GN=SIS8 PE=1 SV=1 Length=1030 Score = 274 bits (701), Expect = 2e-75, Method: Composition-based stats. Identities = 77/284 (27%), Positives = 131/284 (46%), Gaps = 32/284 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G +G+V + G VAVK L D + ++ E+ I++ L H +I+ Sbjct 753 RIGLGSYGEVYRGDWH------GTEVAVKKFLDQDLTGEALEEFRSEVRIMKKLRHPNIV 806 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQH 1018 + G +L +V E++P GSL + R + + + L A GM YLH+ + Sbjct 807 LFMGAVTRP--PNLSIVTEFLPRGSLYRLIHRPNNQLDERRRLRMALDAARGMNYLHSCN 864 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL + N+L+D + +VK+ DFGL++ H Y + W APE L+ Sbjct 865 PMIVHRDLKSPNLLVDKNWVVKVCDFGLSRM---KHSTYLSSKSTAGTAEWMAPEVLRNE 921 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE-RGERLP 1135 DV+S+GV L+EL T + G+M +++ + + RL Sbjct 922 PADEKCDVYSYGVILWELFT---------------LQQPWGKMNPMQVVGAVGFQHRRLD 966 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 PD + L+ CW+T++ RP+F ++ LK + + G Sbjct 967 IPDFVDPAIADLISKCWQTDSKLRPSFAEIMASLKRLQKPVTGS 1010 Score = 254 bits (649), Expect = 1e-68, Method: Composition-based stats. Identities = 75/350 (21%), Positives = 128/350 (37%), Gaps = 45/350 (13%) Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P I + + +S + +EIT +G G+ VY G Sbjct 714 PNSGGERISDKSIGNESSKSDCDDVSDCEILWEEITVGERIGLGSYGEVYRGDW------ 767 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFV 673 G E+ V K LD + F +M ++ H ++ Sbjct 768 ------------------HGTEVAVK-KFLDQDLTGEALEEFRSEVRIMKKLRHPNIVLF 808 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LV 731 G R P +VTE++ G L + R + ++ +A A ++YL + N +V Sbjct 809 MGAVTRPPNLSIVTEFLPRGSLYRLIHRPNNQLDERRRLRMALDAARGMNYLHSCNPMIV 868 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGG 787 H ++ N+L+ + + +K+ D G+ LS + W+APE L Sbjct 869 HRDLKSPNLLVDK-------NWVVKVCDFGLSRMKHSTYLSSKSTAGTAEWMAPEVLRN- 920 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQHRLPEPSCPQLATL 844 D + +G L E+ + P +P + F R+ +P+ P +A L Sbjct 921 -EPADEKCDVYSYGVILWELFTL-QQPWGKMNPMQVVGAVGFQHRRLDIPDFVDPAIADL 978 Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894 S+C + RPSF I+ L RLQ + S +S PT + Sbjct 979 ISKCWQTDSKLRPSFAEIMASLKRLQKPVTGSNIPRPVPSSSSLPTEHEQ 1028 >sp|Q24488|ROR1_DROME Tyrosine-protein kinase transmembrane receptor Ror OS=Drosophila melanogaster OX=7227 GN=Ror PE=1 SV=1 Length=685 Score = 267 bits (683), Expect = 2e-75, Method: Composition-based stats. Identities = 99/301 (33%), Positives = 152/301 (50%), Gaps = 25/301 (8%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 F + ++ + +LGEG FGKV N T VA+KALK + + + +K+EI+ Sbjct 403 NHFTLQDVEFLEELGEGAFGKVYKGQLLQPNKTT-ITVAIKALKENASVKTQQDFKREIE 461 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQLLLF 1003 ++ L H++I+ G ++ + ++ EY+ G L ++L S+ + L Sbjct 462 LISDLKHQNIVCILGVVLNK--EPYCMLFEYMANGDLHEFLISNSPTEGKSLSQLEFLQI 519 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 A QI EGM YL A HY+HRDLAARN L++ +VKI DFGL++ + +YYRV+ Sbjct 520 ALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIY-SSDYYRVQSKSLL 578 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 PV W E + KF SDVWSFGV L+E+ ++ + Sbjct 579 PVRWMPSESILYGKFTTESDVWSFGVVLWEIYSYGMQ--------------PYYGFSNQE 624 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE-KYQGQAPS 1182 + L+ + L P+ CP VY LM CW ++ RPTF ++ LKT HE ++ P Sbjct 625 VINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRLKTWHEGHFKASNPE 684 Query 1183 V 1183 + Sbjct 685 M 685 Score = 244 bits (624), Expect = 1e-67, Method: Composition-based stats. Identities = 62/297 (21%), Positives = 111/297 (37%), Gaps = 43/297 (14%) Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 L + +++ L LG+G VY+G+L + Sbjct 400 LRINHFTLQDVEFLEELGEGAFGKVYKGQLLQPNK---------------------TTIT 438 Query 639 VVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V +K L + F L+S + H ++ + GV + M+ EY+ +G L Sbjct 439 VAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHE 498 Query 698 WLRRERGHV--PMAWK--MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 +L ++ + +A Q++ + YL + VH ++ RN L+ + Sbjct 499 FLISNSPTEGKSLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLV------ 552 Query 754 FIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+SD G+ S + + W+ E + G +T D W FG L EI Sbjct 553 -VKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPSESILYG--KFTTESDVWSFGVVLWEI 609 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 G P S E + + + L PE + +L +C + +RP+F I Sbjct 610 YSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDI 666 >sp|Q9FE20|PBS1_ARATH Serine/threonine-protein kinase PBS1 OS=Arabidopsis thaliana OX=3702 GN=PBS1 PE=1 SV=1 Length=456 Score = 260 bits (664), Expect = 3e-75, Method: Composition-based stats. Identities = 82/299 (27%), Positives = 134/299 (45%), Gaps = 19/299 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 LGEG FG+V Y D TG++VAVK L + G Q + E+ +L L Sbjct 84 MNFHPDTFLGEGGFGRV----YKGRLDSTGQVVAVKQLDRN-GLQGNREFLVEVLMLSLL 138 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICE 1009 +H +++ G C D ++ LV E++PLGSL D+L + ++ + A + Sbjct 139 HHPNLVNLIGYCADGDQR--LLVYEFMPLGSLEDHLHDLPPDKEALDWNMRMKIAAGAAK 196 Query 1010 GMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G+ +LH + I+RD + N+LLD K+ DFGLAK P G + + V Sbjct 197 GLEFLHDKANPPVIYRDFKSSNILLDEGFHPKLSDFGLAKLGPTGDKSH-VSTRVMGTYG 255 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVLR-L 1124 + APE + SDV+SFGV EL+T + S P L+ A+ R Sbjct 256 YCAPEYAMTGQLTVKSDVYSFGVVFLELITGRKAIDSEMPHGEQNLVAWARPLFNDRRKF 315 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV-HEKYQGQAPS 1182 +L + + P + + + C + +A+ RP +++ L + ++ Y Sbjct 316 IKLADPRLKGRFPTRALYQALAVASMCIQEQAATRPLIADVVTALSYLANQAYDPSKDD 374 Score = 228 bits (580), Expect = 8e-64, Method: Composition-based stats. Identities = 64/319 (20%), Positives = 107/319 (34%), Gaps = 63/319 (20%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + LG+G VY+GRL G V +K LD + Sbjct 85 NFHPDTFLGEGGFGRVYKGRLDSTGQ------------------------VVAVKQLDRN 120 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR---ERG 704 F ++S + H +L + G C G + ++V E++ G L+ L ++ Sbjct 121 GLQGNREFLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEFMPLGSLEDHLHDLPPDKE 180 Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 + +M +A A L +L +K +++ + NILL KLSD G Sbjct 181 ALDWNMRMKIAAGAAKGLEFLHDKANPPVIYRDFKSSNILLDE-------GFHPKLSDFG 233 Query 762 VG-LGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 + LG + V + APE G L+ D + FG LE+ +A Sbjct 234 LAKLGPTGDKSHVSTRVMGTYGYCAPEYAMTG--QLTVKSDVYSFGVVFLELITGRKAID 291 Query 816 QSRSPSEKEHFYQRQH------------------RLPEPSCPQLATLTSQCLTYEPTQRP 857 E+ + R P + Q + S C+ + RP Sbjct 292 SEMPHGEQNLVAWARPLFNDRRKFIKLADPRLKGRFPTRALYQALAVASMCIQEQAATRP 351 Query 858 SFRTILRDLTRLQPHNLAD 876 ++ L+ L Sbjct 352 LIADVVTALSYLANQAYDP 370 >sp|Q06548|PBL9_ARATH Probable serine/threonine-protein kinase PBL9 OS=Arabidopsis thaliana OX=3702 GN=PBL9 PE=1 SV=1 Length=410 Score = 258 bits (660), Expect = 3e-75, Method: Composition-based stats. Identities = 86/285 (30%), Positives = 132/285 (46%), Gaps = 18/285 (6%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LGEG FG V D + GTG ++AVK L D G Q W E++ L H Sbjct 74 LGEGGFGCVFKGWIDEKSLTASRPGTGLVIAVKKLNQD-GWQGHQEWLAEVNYLGQFSHR 132 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMA 1012 H++K G C + + LV E++P GSL ++L R + L A +G+A Sbjct 133 HLVKLIGYCLEDEHR--LLVYEFMPRGSLENHLFRRGLYFQPLSWKLRLKVALGAAKGLA 190 Query 1013 YLHAQ--HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 +LH+ I+RD N+LLD++ K+ DFGLAK P G + + V + AP Sbjct 191 FLHSSETRVIYRDFKTSNILLDSEYNAKLSDFGLAKDGPIGDKSH-VSTRVMGTHGYAAP 249 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTELL 1128 E L SDV+SFGV L ELL+ + ++ P+ L+ A+ + R + ++ Sbjct 250 EYLATGHLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRKIFRVI 309 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + + + C+V L C TE RP ++ L+ + Sbjct 310 DNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVVSHLEHIQ 354 Score = 237 bits (604), Expect = 1e-67, Method: Composition-based stats. Identities = 79/349 (23%), Positives = 133/349 (38%), Gaps = 64/349 (18%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRV 610 P P ++ ++ NL SF + + S LG+G V++G + Sbjct 39 PSPRTEGEIL---------QSPNLKSFSFAELKSATRNFRPDSVLGEGGFGCVFKGWI-- 87 Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670 DE L R G L + +K L+ + + + Q SH HL Sbjct 88 ------------DEKSLTASRP-GTGLVIAVKKLNQDGWQGHQEWLAEVNYLGQFSHRHL 134 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV-PMAW--KMVVAQQLASALSYLEN 727 + G C+ ++V E++ G L+ L R + P++W ++ VA A L++L + Sbjct 135 VKLIGYCLEDEHRLLVYEFMPRGSLENHLFRRGLYFQPLSWKLRLKVALGAAKGLAFLHS 194 Query 728 K--NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWL 779 +++ + NILL + KLSD G+ + + + Sbjct 195 SETRVIYRDFKTSNILLD-------SEYNAKLSDFGLAKDGPIGDKSHVSTRVMGTHGYA 247 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGE-----APLQSRSPSEKEH--------- 825 APE L G L+T D + FG LLE+ P R+ E Sbjct 248 APEYLATG--HLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRKI 305 Query 826 FYQRQHRLPEPSC----PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 F +RL + ++ATL+ +CLT E RP+ ++ L +Q Sbjct 306 FRVIDNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVVSHLEHIQ 354 >sp|Q84M95|PBL28_ARATH Probable serine/threonine-protein kinase PBL28 OS=Arabidopsis thaliana OX=3702 GN=PBL28 PE=2 SV=1 Length=375 Score = 257 bits (656), Expect = 4e-75, Method: Composition-based stats. Identities = 82/361 (23%), Positives = 135/361 (37%), Gaps = 27/361 (7%) Query 825 HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884 + +R C L ++ + Sbjct 10 NKRRRSKSYDTDPCTFLFSIIFARWHK------RVYRTAECWQIEDQASQPRKRRFGSSV 63 Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRS 942 LG+G FG+V TGE+VA+K + + Sbjct 64 YTLKEMEEATSSFSDENLLGKGGFGRVYQGTLK-----TGEVVAIKKMDLPTFKKADGER 118 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQ 999 ++ E+DIL L H +++ G C D + LV EY+ G+L+D+L I Sbjct 119 EFRVEVDILSRLDHPNLVSLIGYCADGKHR--FLVYEYMQNGNLQDHLNGIKEAKISWPI 176 Query 1000 LLLFAQQICEGMAYLHAQ-----HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 L A +G+AYLH+ +HRD + NVLLD++ KI DFGLAK +PEG + Sbjct 177 RLRIALGAAKGLAYLHSSSSVGIPIVHRDFKSTNVLLDSNYNAKISDFGLAKLMPEGKDT 236 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ--SPPTKFLELI 1112 V ++ PE K SD+++FGV L ELLT + P + ++ Sbjct 237 -CVTARVLGTFGYFDPEYTSTGKLTLQSDIYAFGVVLLELLTGRRAVDLTQGPNEQNLVL 295 Query 1113 GIAQGQMTVLRLTELLE-RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + +L ++++ R + L C E+ RP+ + + L+ Sbjct 296 QVRNILNDRKKLRKVIDVELPRNSYSMEAITMFADLASRCIRIESKERPSVMDCVKELQL 355 Query 1172 V 1172 + Sbjct 356 I 356 Score = 220 bits (561), Expect = 3e-62, Method: Composition-based stats. Identities = 62/343 (18%), Positives = 119/343 (35%), Gaps = 70/343 (20%) Query 565 RGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 + ++ R S + ++ + + LG+G VY+G L+ Sbjct 50 QASQPRKRRFGSSVYTLKEMEEATSSFSDENLLGKGGFGRVYQGTLKTGE---------- 99 Query 623 DEDPLVPGRDRGQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVR 679 V +K +D D F ++S++ H +L + G C Sbjct 100 ---------------VVAIKKMDLPTFKKADGEREFRVEVDILSRLDHPNLVSLIGYCAD 144 Query 680 GPENIMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKN-----LVHG 733 G +V EY+++G L L + + ++ +A A L+YL + + +VH Sbjct 145 GKHRFLVYEYMQNGNLQDHLNGIKEAKISWPIRLRIALGAAKGLAYLHSSSSVGIPIVHR 204 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV------ERIPWLAPECLPGG 787 + N+LL ++ K+SD G+ ++ + PE G Sbjct 205 DFKSTNVLLD-------SNYNAKISDFGLAKLMPEGKDTCVTARVLGTFGYFDPEYTSTG 257 Query 788 ANSLSTAMDKWGFGATLLEICFDGEA------PLQSRSPSEKEHFYQRQHRLPEPSC--- 838 L+ D + FG LLE+ A P + + + + +L + Sbjct 258 --KLTLQSDIYAFGVVLLELLTGRRAVDLTQGPNEQNLVLQVRNILNDRKKLRKVIDVEL 315 Query 839 ----------PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 A L S+C+ E +RPS +++L + Sbjct 316 PRNSYSMEAITMFADLASRCIRIESKERPSVMDCVKELQLIIY 358 >sp|P43403|ZAP70_HUMAN Tyrosine-protein kinase ZAP-70 OS=Homo sapiens OX=9606 GN=ZAP70 PE=1 SV=1 Length=619 Score = 265 bits (676), Expect = 4e-75, Method: Composition-based stats. Identities = 100/336 (30%), Positives = 151/336 (45%), Gaps = 23/336 (7%) Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899 ++ TL S T EP + S + + + + L Sbjct 283 RIDTLNSDGYTPEPARITSPDKPRPMP--MDTSVYESPYSDPEELKDKKLFLKRDNLLIA 340 Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +LG G+FG V Y VA+K LK +E I+ L + +I Sbjct 341 DIELGCGNFGSVRQGVYRMRKKQ--IDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYI 398 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 ++ G C+ ++L LVME G L +L R I ++ + Q+ GM YL + Sbjct 399 VRLIGVCQ---AEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEK 455 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +++HRDLAARNVLL N KI DFGL+KA+ YY R G P+ WYAPEC+ K Sbjct 456 NFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRK 515 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F SDVWS+GVT++E L++ +M + +E+G+R+ P Sbjct 516 FSSRSDVWSYGVTMWEALSYGQK--------------PYKKMKGPEVMAFIEQGKRMECP 561 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 +CP E+Y LM +CW + RP F + ++ + Sbjct 562 PECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACY 597 Score = 234 bits (598), Expect = 1e-64, Method: Composition-based stats. Identities = 92/486 (19%), Positives = 161/486 (33%), Gaps = 104/486 (21%) Query 445 MSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLR 501 H L + KL DG +L+ L++ + Sbjct 158 HERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPR-KEQGTYALSL---------IYGKT 207 Query 502 LRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLP-------- 553 + + I Q G F ++ +L L+ L+A + L+ C Sbjct 208 VYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLK---LKADGLIYCLKEACPNSSASNASG 264 Query 554 --------------QPGETSNLI-----------IMRGARASPRTLNLSQLSFHRVDQKE 588 P + + I + P ++ S D +E Sbjct 265 AAAPTLPAHPSTLTHPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDTSVYESPYSDPEE 324 Query 589 ITQLS-------------HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 + LG G +V +G R R + Sbjct 325 LKDKKLFLKRDNLLIADIELGCGNFGSVRQGV----------------------YRMRKK 362 Query 636 ELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 ++ V +KVL A +M Q+ + ++ + GVC + ++V E GP Sbjct 363 QIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVC-QAEALMLVMEMAGGGP 421 Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 L +L +R +P++ + Q++ + YLE KN VH ++ RN+LL + Sbjct 422 LHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLL-------VNRHY 474 Query 755 IKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 K+SD G+ + + + W APEC+ S+ D W +G T+ E Sbjct 475 AKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECI--NFRKFSSRSDVWSYGVTMWEA 532 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 G+ P + E F ++ R+ P P+L L S C Y+ RP F T+ + Sbjct 533 LSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQR 592 Query 866 LTRLQP 871 + Sbjct 593 MRACYY 598 >sp|P33497|RYK_AVIR3 Tyrosine-protein kinase transforming protein RYK OS=Avian retrovirus RPL30 OX=31671 GN=V-RYK PE=2 SV=1 Length=442 Score = 259 bits (661), Expect = 4e-75, Method: Composition-based stats. Identities = 91/283 (32%), Positives = 136/283 (48%), Gaps = 27/283 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG FG V +GT + VAVK +K D + + E ++ H ++IK Sbjct 51 LGEGEFGSVMEGRLS-QPEGTPQKVAVKTMKLDNFSHREIEEFLSEAACIKDFDHPNVIK 109 Query 962 YKGCCEDQGEKSL---QLVMEYVPLGSLRDYLPRHSI-------GLAQLLLFAQQICEGM 1011 G C + + + +V+ ++ G L +L R + L LL F I GM Sbjct 110 LLGVCIELSSQQIPKPMVVLPFMKYGDLHSFLLRSRLEMAPQFVPLQMLLKFMVDIALGM 169 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 YL ++ ++HRDLAARN +L +D V + DFGL+K + G +YYR PV W A E Sbjct 170 EYLSSRQFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQGRIAKMPVKWIAIE 228 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 L + + SDVW+FGVT++E+ T + + E L G Sbjct 229 SLADRVYTTKSDVWAFGVTMWEIATRG--------------MTPYPGVQNHEIYEYLFHG 274 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 +RL +P+ C E+Y +M +CW E + RPTF L L+ + E Sbjct 275 QRLKKPENCLDELYDIMSSCWRAEPADRPTFSQLKVHLEKLLE 317 Score = 234 bits (597), Expect = 3e-66, Method: Composition-based stats. Identities = 69/313 (22%), Positives = 119/313 (38%), Gaps = 50/313 (16%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 +L +D+ ++ LG+G +V EGRL + G Sbjct 33 QKLQDVVIDRNALSLGKVLGEGEFGSVMEGRL---------------------SQPEGTP 71 Query 637 LRVVLKV--LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-----GPENIMVTEY 689 +V +K LD H F A+ + H ++ + GVC+ P+ ++V + Sbjct 72 QKVAVKTMKLDNFSHREIEEFLSEAACIKDFDHPNVIKLLGVCIELSSQQIPKPMVVLPF 131 Query 690 VEHGPLDVWLRRERGHV-----PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 +++G L +L R R + P+ + +A + YL ++ +H ++ RN +L Sbjct 132 MKYGDLHSFLLRSRLEMAPQFVPLQMLLKFMVDIALGMEYLSSRQFLHRDLAARNCML-- 189 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKW 798 + ++D G+ S + + W+A E L +T D W Sbjct 190 -----RDDMTVCVADFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRV--YTTKSDVW 242 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 FG T+ EI G P E + RL PE +L + S C EP R Sbjct 243 AFGVTMWEIATRGMTPYPGVQNHEIYEYLFHGQRLKKPENCLDELYDIMSSCWRAEPADR 302 Query 857 PSFRTILRDLTRL 869 P+F + L +L Sbjct 303 PTFSQLKVHLEKL 315 >sp|Q54TM7|DRKD_DICDI Probable serine/threonine-protein kinase drkD OS=Dictyostelium discoideum OX=44689 GN=drkD PE=2 SV=1 Length=1288 Score = 275 bits (704), Expect = 6e-75, Method: Composition-based stats. Identities = 85/316 (27%), Positives = 139/316 (44%), Gaps = 33/316 (10%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 + + + + +G G +G+V + G VAV Sbjct 824 HQFPVPTIPAKIIEVEKPFEWEVPLSEIAIGARIGRGGYGQVFRGSWR------GTEVAV 877 Query 930 KAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 K L + + S ++E+D+L L H +I+ + G C + +V EY+ GSL + Sbjct 878 KMLFNDNVNLKLISDLRKEVDLLCKLRHPNIVLFMGACTEPSSP--CIVTEYLSRGSLAN 935 Query 989 YLPRHSI--GLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGL 1044 L SI L GM YLH+++ IHRDL N+L+D+ VK+ DFGL Sbjct 936 ILLDESIEMDWGLRLQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLVDDSWQVKVADFGL 995 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A + + + W APE L E + +DV+S+ + L+ELLT Sbjct 996 ATV-----KSHTFAKTMCGTTGWVAPEVLAEEGYTEKADVYSYAIVLWELLTRL------ 1044 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 I +++ ++RGERLP P CP + LM CWET+ + RP+F Sbjct 1045 ---------IPYAGKNTMQVVRSIDRGERLPMPAWCPPKYAALMNRCWETDPTHRPSFPE 1095 Query 1165 LIPILKTVHEKYQGQA 1180 ++PI++ + ++Q + Sbjct 1096 ILPIMEGMISEFQKEK 1111 Score = 235 bits (599), Expect = 8e-62, Method: Composition-based stats. Identities = 60/296 (20%), Positives = 109/296 (37%), Gaps = 44/296 (15%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 V EI + +G+G V+ G R V + Sbjct 844 WEVPLSEIAIGARIGRGGYGQVFRGSWRG--------------------------TEVAV 877 Query 642 KVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 K+L D + + + L+ ++ H ++ G C +VTEY+ G L L Sbjct 878 KMLFNDNVNLKLISDLRKEVDLLCKLRHPNIVLFMGACTEPSSPCIVTEYLSRGSLANIL 937 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKL 757 E + ++ + A ++YL ++N ++H ++ N+L+ S +K+ Sbjct 938 LDESIEMDWGLRLQLGFDCARGMTYLHSRNPIIIHRDLKTDNLLVD-------DSWQVKV 990 Query 758 SDPGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 +D G+ + W+APE L + D + + L E+ P Sbjct 991 ADFGLATVKSHTFAKTMCGTTGWVAPEVLAE--EGYTEKADVYSYAIVLWELLTR-LIPY 1047 Query 816 QSRSPSEKEHFYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 ++ + R RLP P+ A L ++C +PT RPSF IL + + Sbjct 1048 AGKNTMQVVRSIDRGERLPMPAWCPPKYAALMNRCWETDPTHRPSFPEILPIMEGM 1103 >sp|Q9H3Y6|SRMS_HUMAN Tyrosine-protein kinase Srms OS=Homo sapiens OX=9606 GN=SRMS PE=1 SV=1 Length=488 Score = 260 bits (664), Expect = 7e-75, Method: Composition-based stats. Identities = 91/447 (20%), Positives = 150/447 (34%), Gaps = 79/447 (18%) Query 439 APPRLVMSIRDGIHGPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPD 495 A P + + + Q L E G +LI S S L+V +++ Sbjct 110 ASPETLSD-QPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVC- 167 Query 496 GMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQP 555 + + + GR FP + EL + + L + C+PQ Sbjct 168 --------HYRVSMAADGSLYLQKGRLFPGLEELLTYYKANWKLIQN---PLLQPCMPQ- 215 Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615 + E LG+G V+EG Sbjct 216 -------------------KAPRQDVWERPHSEFALGRKLGEGYFGEVWEGLWLGS---- 252 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675 L V +KV+ ++ + + + + H L +H Sbjct 253 ---------------------LPVAIKVIKSANMKL-TDLAKEIQTLKGLRHERLIRLHA 290 Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKNLVHGN 734 VC G +VTE + G L +L G + + + A Q+A +SYLE + +VH + Sbjct 291 VCSGGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLGFACQVAEGMSYLEEQRVVHRD 350 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-----EERVERIPWLAPECLPGGAN 789 + RN+L+ K++D G+ + W APE Sbjct 351 LAARNVLVDDGLA-------CKVADFGLARLLKDDIYSPSSSSKIPVKWTAPEAA--NYR 401 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQ 847 S D W FG L E+ G+ P + + E R +RLP P +CP ++ L + Sbjct 402 VFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRGYRLPRPAACPAEVYVLMLE 461 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNL 874 C P +RPSF T+ L + + Sbjct 462 CWRSSPEERPSFATLREKLHAIHRCHP 488 Score = 259 bits (661), Expect = 2e-74, Method: Composition-based stats. Identities = 101/311 (32%), Positives = 141/311 (45%), Gaps = 28/311 (9%) Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926 N + +P D R LGEG+FG+V + + Sbjct 200 NWKLIQNPLLQPCMPQKAPRQDVWERPHSEFALGRKLGEGYFGEVWEGLWLGSLP----- 254 Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VA+K +K + +EI L+ L HE +I+ C G + + +V E + G+L Sbjct 255 VAIKVIK--SANMKLTDLAKEIQTLKGLRHERLIRLHAVCS--GGEPVYIVTELMRKGNL 310 Query 987 RDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 + +L ++ L LL FA Q+ EGM+YL Q +HRDLAARNVL+D+ K+ DFG Sbjct 311 QAFLGTPEGRALRLPPLLGFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFG 370 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 LA+ + + + Y PV W APE F SDVWSFGV L+E+ T+ Sbjct 371 LARLLKD--DIYSPSSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQ---- 424 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163 MT + + RG RLPRP CP EVY LM CW + RP+F Sbjct 425 ----------CPYEGMTNHETLQQIMRGYRLPRPAACPAEVYVLMLECWRSSPEERPSFA 474 Query 1164 NLIPILKTVHE 1174 L L +H Sbjct 475 TLREKLHAIHR 485 >sp|Q9LDZ5|PBL21_ARATH Probable serine/threonine-protein kinase PBL21 OS=Arabidopsis thaliana OX=3702 GN=PBL21 PE=1 SV=1 Length=381 Score = 256 bits (655), Expect = 7e-75, Method: Composition-based stats. Identities = 83/296 (28%), Positives = 133/296 (45%), Gaps = 25/296 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG+V D +G++VA+K L D G Q + E+ +L L+H +++ Sbjct 84 LGEGGFGRVYKGRLD-----SGQVVAIKQLNPD-GLQGNREFIVEVLMLSLLHHPNLVTL 137 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLH-- 1015 G C ++ LV EY+P+GSL D+L + + + A G+ YLH Sbjct 138 IGYCTSGDQR--LLVYEYMPMGSLEDHLFDLESNQEPLSWNTRMKIAVGAARGIEYLHCT 195 Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 I+RDL + N+LLD + K+ DFGLAK P G + V + APE Sbjct 196 ANPPVIYRDLKSANILLDKEFSPKLSDFGLAKLGPVGDRTH-VSTRVMGTYGYCAPEYAM 254 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQMTVL-RLTELLERGE 1132 K SD++ FGV L EL+T + + L+ ++ + + L++ Sbjct 255 SGKLTVKSDIYCFGVVLLELITGRKAIDLGQKQGEQNLVTWSRPYLKDQKKFGHLVDPSL 314 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV------HEKYQGQAPS 1182 R P +C ++ C EA +RP +++ L+ + HE +PS Sbjct 315 RGKYPRRCLNYAIAIIAMCLNEEAHYRPFIGDIVVALEYLAAQSRSHEARNVSSPS 370 Score = 235 bits (599), Expect = 2e-67, Method: Composition-based stats. Identities = 78/353 (22%), Positives = 128/353 (36%), Gaps = 67/353 (19%) Query 557 ETSNLIIMRGARASPRTLN-LSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGS 613 E+ + I++ G SP +F + + +++ LG+G VY+GRL Sbjct 43 ESISGILVNGKVNSPIPGGGARSFTFKELAAATRNFREVNLLGEGGFGRVYKGRL----- 97 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 D GQ V +K L+P F ++S + H +L + Sbjct 98 ------------------DSGQ--VVAIKQLNPDGLQGNREFIVEVLMLSLLHHPNLVTL 137 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYLE---N 727 G C G + ++V EY+ G L+ L E P++W +M +A A + YL N Sbjct 138 IGYCTSGDQRLLVYEYMPMGSLEDHLFDLESNQEPLSWNTRMKIAVGAARGIEYLHCTAN 197 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERV-----ERIPWLAP 781 +++ ++ NILL + KLSD G+ LG + V + AP Sbjct 198 PPVIYRDLKSANILLDKEFSP-------KLSDFGLAKLGPVGDRTHVSTRVMGTYGYCAP 250 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-------- 833 E G L+ D + FG LLE+ +A + E+ + L Sbjct 251 EYAMSG--KLTVKSDIYCFGVVLLELITGRKAIDLGQKQGEQNLVTWSRPYLKDQKKFGH 308 Query 834 ----------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 P + + CL E RP I+ L L + + Sbjct 309 LVDPSLRGKYPRRCLNYAIAIIAMCLNEEAHYRPFIGDIVVALEYLAAQSRSH 361 >sp|P04629|NTRK1_HUMAN High affinity nerve growth factor receptor OS=Homo sapiens OX=9606 GN=NTRK1 PE=1 SV=4 Length=796 Score = 268 bits (685), Expect = 8e-75, Method: Composition-based stats. Identities = 103/312 (33%), Positives = 156/312 (50%), Gaps = 40/312 (13%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 +R + +LGEG FGKV L C++ + +VAVKALK + R +++E Sbjct 503 HHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALK-EASESARQDFQREA 561 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--------------- 993 ++L L H+HI+++ G C + + L +V EY+ G L +L H Sbjct 562 ELLTMLQHQHIVRFFGVCTEG--RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAP 619 Query 994 -SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 +GL QLL A Q+ GM YL H++HRDLA RN L+ +VKIGDFG+++ + Sbjct 620 GPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIY-ST 678 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 +YYRV P+ W PE + KF SDVWSFGV L+E+ T+ Sbjct 679 DYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQ------------ 726 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 Q++ + + +G L RP CP EVY +M+ CW+ E R + +++ L+ + Sbjct 727 --PWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQAL 784 Query 1173 HEKYQGQAPSVF 1184 QAP V+ Sbjct 785 -----AQAPPVY 791 Score = 262 bits (670), Expect = 9e-73, Method: Composition-based stats. Identities = 78/345 (23%), Positives = 129/345 (37%), Gaps = 52/345 (15%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 P E + +P+ S H + +++I LG+G V+ Sbjct 477 SPTEGKGSGLQGHIIENPQY--FSDACVHHIKRRDIVLKWELGEGAFGKVF--------- 525 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 + + L+P +D+ + V +K L + F A L++ + H H+ Sbjct 526 -------LAECHNLLPEQDK---MLVAVKALKEASESARQDFQREAELLTMLQHQHIVRF 575 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRE--------------RGHVPMAWKMVVAQQLA 719 GVC G +MV EY+ HG L+ +LR G + + + VA Q+A Sbjct 576 FGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVA 635 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE------RV 773 + + YL + VH ++ RN L+ G +K+ D G+ S + + Sbjct 636 AGMVYLAGLHFVHRDLATRNCLV-------GQGLVVKIGDFGMSRDIYSTDYYRVGGRTM 688 Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833 I W+ PE + +T D W FG L EI G+ P S +E + L Sbjct 689 LPIRWMPPESIL--YRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGREL 746 Query 834 --PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 P P++ + C EP QR S + + L L Sbjct 747 ERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVY 791 >sp|P42679|MATK_HUMAN Megakaryocyte-associated tyrosine-protein kinase OS=Homo sapiens OX=9606 GN=MATK PE=1 SV=1 Length=507 Score = 260 bits (665), Expect = 1e-74, Method: Composition-based stats. Identities = 111/370 (30%), Positives = 167/370 (45%), Gaps = 46/370 (12%) Query 821 SEKEHFY--QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + H+ R L L + T+L Sbjct 164 RDVIHYRVLHRDGHLTIDEAVFFCNLMDM-------VEHYSKDKGAICTKLVRPKRKHGT 216 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 + A + + ++L +GEG FG V Y G+ VAVK +K D Sbjct 217 KSAEEELARAGWLLNLQHLTLGAQIGEGEFGAVLQGEYL------GQKVAVKNIKCDVTA 270 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---I 995 Q + E ++ + HE++++ G QG L +VME+V G+L ++L + Sbjct 271 Q---AFLDETAVMTKMQHENLVRLLGVILHQG---LYIVMEHVSKGNLVNFLRTRGRALV 324 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 AQLL F+ + EGM YL ++ +HRDLAARN+L+ D + K+ DFGLAKA +G + Sbjct 325 NTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSS 384 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 R+ PV W APE LK KF SDVWSFGV L+E+ ++ + Sbjct 385 RL------PVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRA--------------P 424 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 +M++ ++E +E+G R+ P+ CP V+ LM +CWE E + RP F L L E Sbjct 425 YPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLA--REL 482 Query 1176 YQGQAPSVFS 1185 AP+ S Sbjct 483 RSAGAPASVS 492 Score = 255 bits (652), Expect = 5e-73, Method: Composition-based stats. Identities = 99/429 (23%), Positives = 169/429 (39%), Gaps = 72/429 (17%) Query 439 APPRLVMSIRDGIHGPLLEPFVQAKLRP-EDGLYLIHWSTSHPYRLILTVAQRSQAPDGM 497 A P+L S+ HG + +L+P EDGL+L+ S HP +L V+ Sbjct 113 ADPKL--SLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVI--- 167 Query 498 QSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGE 557 + + +DG ++ F ++ ++ G C L R + Sbjct 168 ------HYRVLHRDGHLTID-EAVFFCNLMDMVEHYSKDK---GAICTKLVRPKRKHGTK 217 Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 ++ + R ++ + +T + +G+G V +G + Sbjct 218 SAEEELARAG--------------WLLNLQHLTLGAQIGEGEFGAVLQGEYLGQ------ 257 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 +V +K + A AF + ++M+++ H +L + GV Sbjct 258 --------------------KVAVKNIKCDVT--AQAFLDETAVMTKMQHENLVRLLGVI 295 Query 678 VRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736 + +V E+V G L +LR R R V A + + +A + YLE+K LVH ++ Sbjct 296 LHQG-LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLA 354 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-EERVERIPWLAPECLPGGANSLSTAM 795 RNIL++ +A K+SD G+ + + W APE L G ++ Sbjct 355 ARNILVSEDLVA-------KVSDFGLAKAERKGLDSSRLPVKWTAPEALKHG--KFTSKS 405 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEP 853 D W FG L E+ G AP S E ++ +R+ P CP + L S C EP Sbjct 406 DVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEP 465 Query 854 TQRPSFRTI 862 +RP FR + Sbjct 466 ARRPPFRKL 474 >sp|P07949|RET_HUMAN Proto-oncogene tyrosine-protein kinase receptor Ret OS=Homo sapiens OX=9606 GN=RET PE=1 SV=3 Length=1114 Score = 273 bits (699), Expect = 1e-74, Method: Composition-based stats. Identities = 106/317 (33%), Positives = 147/317 (46%), Gaps = 43/317 (14%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYC-YDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 F ++ L + LGEG FGKV + VAVK LK + P Sbjct 715 PKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLS 774 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-------------- 992 E ++L+ + H H+IK G C G L L++EY GSLR +L Sbjct 775 EFNVLKQVNHPHVIKLYGACSQDG--PLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGS 832 Query 993 -----------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 ++ + L+ FA QI +GM YL +HRDLAARN+L+ R +KI D Sbjct 833 RNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISD 892 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGL++ V E Y + R G PV W A E L ++ + SDVWSFGV L+E++T Sbjct 893 FGLSRDVYEEDSYVK-RSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVT----- 946 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 L G + RL LL+ G R+ RPD C E+Y LM CW+ E RP Sbjct 947 ---------LGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPV 997 Query 1162 FENLIPILKTVHEKYQG 1178 F ++ L+ + K + Sbjct 998 FADISKDLEKMMVKRRD 1014 Score = 239 bits (609), Expect = 3e-63, Method: Composition-based stats. Identities = 77/369 (21%), Positives = 129/369 (35%), Gaps = 68/369 (18%) Query 547 LRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSF-------HRVDQKEITQLSHLGQGT 599 RR P S+ R +S +F +K + LG+G Sbjct 676 FRRPAQAFPVSYSSSG-ARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGE 734 Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYET 658 V + + R V +K+L + Sbjct 735 FGKVVKA-------------------TAFHLKGRAGYTTVAVKMLKENASPSELRDLLSE 775 Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-------------- 704 +++ QV+H H+ ++G C + +++ EY ++G L +LR R Sbjct 776 FNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNS 835 Query 705 ---------HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 + M + A Q++ + YL LVH ++ RNIL+A + Sbjct 836 SSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE-------GRKM 888 Query 756 KLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 K+SD G+ + V+R + W+A E L + +T D W FG L EI Sbjct 889 KISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFD--HIYTTQSDVWSFGVLLWEIVT 946 Query 810 DGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 G P P + + HR+ P+ ++ L QC EP +RP F I +DL Sbjct 947 LGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLE 1006 Query 868 RLQPHNLAD 876 ++ Sbjct 1007 KMMVKRRDY 1015 >sp|Q91009|NTRK1_CHICK High affinity nerve growth factor receptor (Fragment) OS=Gallus gallus OX=9031 GN=NTRK1 PE=1 SV=1 Length=778 Score = 267 bits (683), Expect = 1e-74, Method: Composition-based stats. Identities = 101/318 (32%), Positives = 156/318 (49%), Gaps = 40/318 (13%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY---CYDPTNDGTGEMVAVKAL 932 + + + +R + +LGEG FGKV L P + T +VAVKAL Sbjct 472 NFIENPQYFCNACVHHVQRRDIVLKWELGEGAFGKVFLAECSHLLPEQEKT--LVAVKAL 529 Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992 K + R +++E ++L L HEHI+K+ G C + L +V EY+ G L +L Sbjct 530 K-EVTENARLDFQREAELLTVLQHEHIVKFYGVCTEGD--PLIMVFEYMKHGDLNRFLRS 586 Query 993 HS----------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036 H + L+ +L A QI GM YL + H++HRDLA RN L+ +D + Sbjct 587 HGPDAKILDQGQGQPCGQLTLSHMLQIATQIASGMVYLASLHFVHRDLATRNCLVGHDLV 646 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 VKIGDFG+++ + +YYRV P+ W PE + KF SD+WSFGV L+E+ T Sbjct 647 VKIGDFGMSRDIY-STDYYRVGGRTMLPIRWMPPESILYRKFTTESDIWSFGVVLWEIFT 705 Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156 + Q++ E + +G L RP CP EVY +M++CW+ E Sbjct 706 YGKQ--------------PWYQLSNTEAIECITQGRELERPRTCPSEVYDIMQSCWQREP 751 Query 1157 SFRPTFENLIPILKTVHE 1174 R + +++ L+ + + Sbjct 752 QQR-SIQDIHSRLQALVK 768 Score = 259 bits (662), Expect = 8e-72, Method: Composition-based stats. Identities = 70/298 (23%), Positives = 114/298 (38%), Gaps = 50/298 (17%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 H V +++I LG+G V+ ++ V + Sbjct 486 HHVQRRDIVLKWELGEGAFGKVFLAECSHLLPEQ-------------------EKTLVAV 526 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 K L + L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR Sbjct 527 KALKEVTENARLDFQREAELLTVLQHEHIVKFYGVCTEGDPLIMVFEYMKHGDLNRFLRS 586 Query 702 ER--------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 G + ++ + +A Q+AS + YL + + VH ++ RN L+ Sbjct 587 HGPDAKILDQGQGQPCGQLTLSHMLQIATQIASGMVYLASLHFVHRDLATRNCLV----- 641 Query 748 AEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFG 801 G +K+ D G+ S + + I W+ PE + +T D W FG Sbjct 642 --GHDLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESIL--YRKFTTESDIWSFG 697 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857 L EI G+ P S +E + L P ++ + C EP QR Sbjct 698 VVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRTCPSEVYDIMQSCWQREPQQRS 755 >sp|Q06807|TIE2_BOVIN Angiopoietin-1 receptor OS=Bos taurus OX=9913 GN=TEK PE=2 SV=1 Length=1125 Score = 273 bits (698), Expect = 1e-74, Method: Composition-based stats. Identities = 98/300 (33%), Positives = 143/300 (48%), Gaps = 40/300 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961 +GEG+FG+V DG A+K +K + E+++L L +H +II Sbjct 831 IGEGNFGQVLKARIK--KDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIIN 888 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFA 1004 G CE +G L L +EY P G+L D+L + ++ QLL FA Sbjct 889 LLGACEHRG--YLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFA 946 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 + GM YL + +IHRDLAARN+L+ + + KI DFGL++ G E Y + G P Sbjct 947 ADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSR----GQEVYVKKTMGRLP 1002 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 V W A E L + SDVWS+GV L+E+++ L G MT L Sbjct 1003 VRWMAIESLNYSVYTTNSDVWSYGVLLWEIVS--------------LGGTPYCGMTCAEL 1048 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 E L +G RL +P C EVY LM+ CW + RP+F ++ L + E+ + + Sbjct 1049 YEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTL 1108 Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 72/353 (20%), Positives = 133/353 (38%), Gaps = 58/353 (16%) Query 557 ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616 + L + R A+ +P L ++ + +++ +G+G V + R++ +G Sbjct 798 NSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDV-----IGEGNFGQVLKARIKKDGL--- 849 Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQV-SHTHLAFVH 674 + +K + + D F ++ ++ H ++ + Sbjct 850 -------------------RMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLL 890 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLA 719 G C + EY HG L +LR+ R + + A +A Sbjct 891 GACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVA 950 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA-LSREERVERIP- 777 + YL K +H ++ RNIL+ G + K++D G+ G + ++ + R+P Sbjct 951 RGMDYLSQKQFIHRDLAARNILV-------GENYVAKIADFGLSRGQEVYVKKTMGRLPV 1003 Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--P 834 W+A E L + +T D W +G L EI G P + +E + +RL P Sbjct 1004 RWMAIESL--NYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKP 1061 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 ++ L QC +P +RPSF IL L R+ V T + Sbjct 1062 LNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTY 1114 >sp|Q4H3K6|FGFR_CIOIN Fibroblast growth factor receptor OS=Ciona intestinalis OX=7719 GN=FGFR PE=2 SV=1 Length=747 Score = 266 bits (681), Expect = 1e-74, Method: Composition-based stats. Identities = 108/400 (27%), Positives = 158/400 (40%), Gaps = 54/400 (14%) Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 + FG I + + K RL P S+ EP Sbjct 290 IYIFGVVCFIILLAFIVYMCNSRYQNK-----DPPRLIPIENPDNIPPMSK--MEEPVML 342 Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916 + L + + + + + EG FG+V Sbjct 343 FGNEQAW------RRMCLPHADHIEINIQPDLQWELKREDILLHERIDEGFFGQVFRADL 396 Query 917 DPTNDGTGEMV--AVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKS 973 G E V AVK LK+ + E+D ++ + H++I+ G C G Sbjct 397 IRCAGGRKEKVDAAVKMLKSTRTEKDMLDLLTEMDQMKRVGKHKNIVNLLGVCTQNG--I 454 Query 974 LQLVMEYVPLGSLRDYLPRH---------------------SIGLAQLLLFAQQICEGMA 1012 L LV EY G+LRDYL R+ + L L+ + Q+ GM Sbjct 455 LWLVTEYAQKGNLRDYLRRNRPSELQYELSTPDSPAPPRDEPLTLRALMSASHQVARGME 514 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 YL + IHRDLAARNVL+ ND ++KI DFGLA+ + ++YYR G P W A E Sbjct 515 YLSQKKCIHRDLAARNVLVANDFVMKIADFGLARDIR-SNDYYRKETRGHLPYKWMALEA 573 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + F +A+DVWSFG+ L+E+ + L G + L L G+ Sbjct 574 MTDNMFTHATDVWSFGILLWEIFS--------------LGGSPYPGVKTHDLVRFLRNGD 619 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 RL +P E+Y LM++CWE RP F L+ L + Sbjct 620 RLEQPQFASSELYRLMRDCWEESPRRRPQFRQLVEDLDRM 659 Score = 231 bits (588), Expect = 3e-62, Method: Composition-based stats. Identities = 73/352 (21%), Positives = 130/352 (37%), Gaps = 70/352 (20%) Query 547 LRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606 RR CLP A +N+ + +++I + +G V+ Sbjct 349 WRRMCLPH--------------ADHIEINIQPDLQWELKREDILLHERIDEGFFGQVFRA 394 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV 665 L + R +++ +K+L + + + M +V Sbjct 395 DL------------------IRCAGGRKEKVDAAVKMLKSTRTEKDMLDLLTEMDQMKRV 436 Query 666 -SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-----------------VP 707 H ++ + GVC + +VTEY + G L +LRR R P Sbjct 437 GKHKNIVNLLGVCTQNGILWLVTEYAQKGNLRDYLRRNRPSELQYELSTPDSPAPPRDEP 496 Query 708 MAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 + + ++ + Q+A + YL K +H ++ RN+L+A +K++D G+ Sbjct 497 LTLRALMSASHQVARGMEYLSQKKCIHRDLAARNVLVAN-------DFVMKIADFGLARD 549 Query 766 ALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 S + + W+A E + + A D W FG L EI G +P Sbjct 550 IRSNDYYRKETRGHLPYKWMALEAMTDNM--FTHATDVWSFGILLWEIFSLGGSPYPGVK 607 Query 820 PSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + F + RL P+ + +L L C P +RP FR ++ DL R+ Sbjct 608 THDLVRFLRNGDRLEQPQFASSELYRLMRDCWEESPRRRPQFRQLVEDLDRM 659 >sp|G3V9H8|RET_RAT Proto-oncogene tyrosine-protein kinase receptor Ret OS=Rattus norvegicus OX=10116 GN=Ret PE=1 SV=1 Length=1115 Score = 273 bits (698), Expect = 1e-74, Method: Composition-based stats. Identities = 112/380 (29%), Positives = 162/380 (43%), Gaps = 47/380 (12%) Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS- 884 F ++ P + + C P Q R ++ + ++V+ Sbjct 656 FCIHRYHKHAHKPPIASAEMTFC---RPAQGFPISYSSSGTRRPSLDSMENQVSVDSFKI 712 Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYC-YDPTNDGTGEMVAVKALKADCGPQHRSG 943 P F ++ L + LGEG FGKV + VAVK LK + Sbjct 713 PEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRD 772 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------------ 991 E ++L+ + H H+IK G C G L L++EY GSLR +L Sbjct 773 LLSEFNLLKQVNHPHVIKLYGACSQDG--PLLLIVEYAKYGSLRGFLRDSRKIGPAYVSS 830 Query 992 -------------RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 + + L+ FA QI GM YL +HRDLAARN+L+ R +K Sbjct 831 GGSRNSSSLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMK 890 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 I DFGL++ V E Y + + G PV W A E L ++ + SDVWSFGV L+E++T Sbjct 891 ISDFGLSRDVYEEDSYVK-KSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVT-- 947 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 L G + RL LL+ G R+ RPD C E+Y LM CW+ E Sbjct 948 ------------LGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDK 995 Query 1159 RPTFENLIPILKTVHEKYQG 1178 RP F ++ L+ + K + Sbjct 996 RPVFADISKDLEKMMVKSRD 1015 Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 71/336 (21%), Positives = 124/336 (37%), Gaps = 60/336 (18%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 + S + + + +K + LG+G V + Sbjct 703 NQVSVDSFKIPEDPKWEFPRKNLVLGKTLGEGEFGKVVKA-------------------T 743 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 + R V +K+L + +L+ QV+H H+ ++G C + ++ Sbjct 744 AFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNLLKQVNHPHVIKLYGACSQDGPLLL 803 Query 686 VTEYVEHGPLDVWLRRERG-----------------------HVPMAWKMVVAQQLASAL 722 + EY ++G L +LR R + M + A Q++ + Sbjct 804 IVEYAKYGSLRGFLRDSRKIGPAYVSSGGSRNSSSLDHPDERVLTMGDLISFAWQISRGM 863 Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------I 776 YL LVH ++ RNIL+A +K+SD G+ + V++ + Sbjct 864 QYLAEMKLVHRDLAARNILVAE-------GRKMKISDFGLSRDVYEEDSYVKKSKGRIPV 916 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--P 834 W+A E L + +T D W FG L EI G P P + + HR+ P Sbjct 917 KWMAIESLFD--HIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERP 974 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + ++ L QC EP +RP F I +DL ++ Sbjct 975 DNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMM 1010 >sp|Q02763|TIE2_HUMAN Angiopoietin-1 receptor OS=Homo sapiens OX=9606 GN=TEK PE=1 SV=2 Length=1124 Score = 273 bits (698), Expect = 1e-74, Method: Composition-based stats. Identities = 98/300 (33%), Positives = 143/300 (48%), Gaps = 40/300 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961 +GEG+FG+V DG A+K +K + E+++L L +H +II Sbjct 830 IGEGNFGQVLKARIK--KDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIIN 887 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFA 1004 G CE +G L L +EY P G+L D+L + ++ QLL FA Sbjct 888 LLGACEHRG--YLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFA 945 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 + GM YL + +IHRDLAARN+L+ + + KI DFGL++ G E Y + G P Sbjct 946 ADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSR----GQEVYVKKTMGRLP 1001 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 V W A E L + SDVWS+GV L+E+++ L G MT L Sbjct 1002 VRWMAIESLNYSVYTTNSDVWSYGVLLWEIVS--------------LGGTPYCGMTCAEL 1047 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 E L +G RL +P C EVY LM+ CW + RP+F ++ L + E+ + + Sbjct 1048 YEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTL 1107 Score = 241 bits (615), Expect = 4e-64, Method: Composition-based stats. Identities = 74/381 (19%), Positives = 138/381 (36%), Gaps = 58/381 (15%) Query 529 LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKE 588 + + + R F R + L + R + +P L ++ + ++ Sbjct 769 ILQLKRANVQRRMAQAFQNVREEPAVQFNSGTLALNRKVKNNPDPTIYPVLDWNDIKFQD 828 Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-S 647 + +G+G V + R++ +G + +K + + Sbjct 829 V-----IGEGNFGQVLKARIKKDGL----------------------RMDAAIKRMKEYA 861 Query 648 HHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER--- 703 D F ++ ++ H ++ + G C + EY HG L +LR+ R Sbjct 862 SKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLE 921 Query 704 ------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 + + A +A + YL K +H ++ RNIL+ G Sbjct 922 TDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILV-------GE 974 Query 752 SPFIKLSDPGVGLGA-LSREERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + K++D G+ G + ++ + R+P W+A E L + +T D W +G L EI Sbjct 975 NYVAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESL--NYSVYTTNSDVWSYGVLLWEIV 1032 Query 809 FDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 G P + +E + +RL P ++ L QC +P +RPSF IL L Sbjct 1033 SLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSL 1092 Query 867 TRLQPHNLADVLTVNPDSPAS 887 R+ V T + Sbjct 1093 NRMLEERKTYVNTTLYEKFTY 1113 >sp|Q02858|TIE2_MOUSE Angiopoietin-1 receptor OS=Mus musculus OX=10090 GN=Tek PE=1 SV=2 Length=1122 Score = 273 bits (697), Expect = 2e-74, Method: Composition-based stats. Identities = 98/300 (33%), Positives = 143/300 (48%), Gaps = 40/300 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIK 961 +GEG+FG+V DG A+K +K + E+++L L +H +II Sbjct 828 IGEGNFGQVLKARIK--KDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIIN 885 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFA 1004 G CE +G L L +EY P G+L D+L + ++ QLL FA Sbjct 886 LLGACEHRG--YLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFA 943 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 + GM YL + +IHRDLAARN+L+ + + KI DFGL++ G E Y + G P Sbjct 944 ADVARGMDYLSQKQFIHRDLAARNILVGENYIAKIADFGLSR----GQEVYVKKTMGRLP 999 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 V W A E L + SDVWS+GV L+E+++ L G MT L Sbjct 1000 VRWMAIESLNYSVYTTNSDVWSYGVLLWEIVS--------------LGGTPYCGMTCAEL 1045 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 E L +G RL +P C EVY LM+ CW + RP+F ++ L + E+ + + Sbjct 1046 YEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTL 1105 Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 72/353 (20%), Positives = 133/353 (38%), Gaps = 58/353 (16%) Query 557 ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616 + L + R A+ +P L ++ + +++ +G+G V + R++ +G Sbjct 795 NSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDV-----IGEGNFGQVLKARIKKDGL--- 846 Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQV-SHTHLAFVH 674 + +K + + D F ++ ++ H ++ + Sbjct 847 -------------------RMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLL 887 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLA 719 G C + EY HG L +LR+ R + + A +A Sbjct 888 GACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVA 947 Query 720 SALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA-LSREERVERIP- 777 + YL K +H ++ RNIL+ G + K++D G+ G + ++ + R+P Sbjct 948 RGMDYLSQKQFIHRDLAARNILV-------GENYIAKIADFGLSRGQEVYVKKTMGRLPV 1000 Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--P 834 W+A E L + +T D W +G L EI G P + +E + +RL P Sbjct 1001 RWMAIESL--NYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKP 1058 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 ++ L QC +P +RPSF IL L R+ V T + Sbjct 1059 LNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTTLYEKFTY 1111 >sp|Q8VYG0|LRL13_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 1.3 OS=Arabidopsis thaliana OX=3702 GN=LRK10L-1.3 PE=2 SV=1 Length=686 Score = 264 bits (675), Expect = 2e-74, Method: Composition-based stats. Identities = 92/371 (25%), Positives = 155/371 (42%), Gaps = 19/371 (5%) Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL-TVNP 882 +R+ + + L+T T Y + P+ TI L P +V Sbjct 284 IFIRRRKKLATQYTNKGLSTTTPYSSNYTMSNTPTSTTISGSNHSLVPSISNLGNGSVYS 343 Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 + ++LG+G FG V G VAVK L + + Sbjct 344 GIQVFSYEELEEATENFSKELGDGGFGTVYYGTLK-----DGRAVAVKRL-FERSLKRVE 397 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGL 997 +K EIDIL++L H +++ G C + + L LV EY+ G+L ++L + I Sbjct 398 QFKNEIDILKSLKHPNLVILYG-CTTRHSRELLLVYEYISNGTLAEHLHGNQAQSRPICW 456 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 L A + ++YLHA IHRD+ N+LLD++ VK+ DFGL++ P + Sbjct 457 PARLQIAIETASALSYLHASGIIHRDVKTTNILLDSNYQVKVADFGLSRLFPMDQTHIST 516 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQ 1116 G + PE + Y+ SDV+SFGV L EL++ ++ + + L +A Sbjct 517 APQG--TPGYVDPEYYQCYRLNEKSDVYSFGVVLSELISSKEAVDITRHRHDINLANMAI 574 Query 1117 GQMTVLRLTELLERGE---RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 ++ + EL + R P K V L C + E RP+ + ++ +L+ + Sbjct 575 SKIQNDAVHELADLSLGFARDPSVKKMMSSVAELAFRCLQQERDVRPSMDEIVEVLRVIQ 634 Query 1174 EKYQGQAPSVF 1184 + + V Sbjct 635 KDGISDSKDVV 645 Score = 211 bits (538), Expect = 3e-56, Method: Composition-based stats. Identities = 59/316 (19%), Positives = 112/316 (35%), Gaps = 44/316 (14%) Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 + S+ +++ LG G VY G L+ Sbjct 344 GIQVFSYEELEEATENFSKELGDGGFGTVYYGTLKDGR---------------------- 381 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHG 693 V +K L F ++ + H +L ++G R E ++V EY+ +G Sbjct 382 ---AVAVKRLFERSLKRVEQFKNEIDILKSLKHPNLVILYGCTTRHSRELLLVYEYISNG 438 Query 694 PLDVWLRRERGHV-PMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 L L + P+ W ++ +A + ASALSYL ++H +V NILL Sbjct 439 TLAEHLHGNQAQSRPICWPARLQIAIETASALSYLHASGIIHRDVKTTNILLD------- 491 Query 751 TSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 ++ +K++D G+ + + ++ PE L+ D + FG L Sbjct 492 SNYQVKVADFGLSRLFPMDQTHISTAPQGTPGYVDPEYYQ--CYRLNEKSDVYSFGVVLS 549 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 E+ EA +R + ++ + +LA L S +P+ + ++ Sbjct 550 ELISSKEAVDITRHRHDINLANMAISKIQNDAVHELADL-SLGFARDPSVKKMMSSVAEL 608 Query 866 LTRLQPHNLADVLTVN 881 R +++ Sbjct 609 AFRCLQQERDVRPSMD 624 >sp|Q0WRY5|PBL7_ARATH Probable serine/threonine-protein kinase PBL7 OS=Arabidopsis thaliana OX=3702 GN=PBL7 PE=1 SV=1 Length=378 Score = 254 bits (650), Expect = 2e-74, Method: Composition-based stats. Identities = 80/291 (27%), Positives = 133/291 (46%), Gaps = 18/291 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R +K +GEG FG+V Y T + A+K L + G Q + E+ +L L Sbjct 71 RNFRKECLIGEGGFGRV----YKGYLASTSQTAAIKQLDHN-GLQGNREFLVEVLMLSLL 125 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICE 1009 +H +++ G C D ++ LV EY+PLGSL D+L + + + A + Sbjct 126 HHPNLVNLIGYCADGDQR--LLVYEYMPLGSLEDHLHDISPGKQPLDWNTRMKIAAGAAK 183 Query 1010 GMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G+ YLH + I+RDL N+LLD+D K+ DFGLAK P G + + V Sbjct 184 GLEYLHDKTMPPVIYRDLKCSNILLDDDYFPKLSDFGLAKLGPVGDKSH-VSTRVMGTYG 242 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLR-L 1124 + APE + SDV+SFGV L E++T + S T L+ A+ R Sbjct 243 YCAPEYAMTGQLTLKSDVYSFGVVLLEIITGRKAIDSSRSTGEQNLVAWARPLFKDRRKF 302 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 +++ + + P + + + C + + + RP +++ L + + Sbjct 303 SQMADPMLQGQYPPRGLYQALAVAAMCVQEQPNLRPLIADVVTALSYLASQ 353 Score = 235 bits (599), Expect = 3e-67, Method: Composition-based stats. Identities = 73/335 (22%), Positives = 119/335 (36%), Gaps = 66/335 (20%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 +T S+L+ + + +G+G VY+G L Sbjct 59 QTFTFSELAT---ATRNFRKECLIGEGGFGRVYKGYLA---------------------- 93 Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +K LD + F ++S + H +L + G C G + ++V EY+ Sbjct 94 --STSQTAAIKQLDHNGLQGNREFLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEYMP 151 Query 692 HGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745 G L+ L G P+ W +M +A A L YL +K +++ ++ NILL Sbjct 152 LGSLEDHLHDISPGKQPLDWNTRMKIAAGAAKGLEYLHDKTMPPVIYRDLKCSNILLD-- 209 Query 746 GLAEGTSPFIKLSDPGVG-LGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWG 799 F KLSD G+ LG + + V + APE G L+ D + Sbjct 210 -----DDYFPKLSDFGLAKLGPVGDKSHVSTRVMGTYGYCAPEYAMTG--QLTLKSDVYS 262 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------------------RLPEPSCPQL 841 FG LLEI +A SRS E+ + + P Q Sbjct 263 FGVVLLEIITGRKAIDSSRSTGEQNLVAWARPLFKDRRKFSQMADPMLQGQYPPRGLYQA 322 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 + + C+ +P RP ++ L+ L Sbjct 323 LAVAAMCVQEQPNLRPLIADVVTALSYLASQKFDP 357 >sp|Q95YM9|FGFR_HALRO Fibroblast growth factor receptor OS=Halocynthia roretzi OX=7729 GN=FGFR PE=2 SV=1 Length=763 Score = 266 bits (680), Expect = 2e-74, Method: Composition-based stats. Identities = 105/407 (26%), Positives = 164/407 (40%), Gaps = 64/407 (16%) Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 ++ + L + +++ + P P L + P P I Sbjct 292 IIIYVMCGVLVILFGLAVVLVLYYHCYNGKDP----PMLVRI------ENPDNIPPMTKI 341 Query 863 LRDLTRL------QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916 Q + + + + + L EG FG+V Sbjct 342 EHPTMLFGNTQAWQRMCMPMQEPFEFNIQLDLQWELQREDITLVERLDEGFFGQVFKADL 401 Query 917 DPTNDGTGEMV--AVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKS 973 N+ E + AVK LK + + E+D ++ + H++II G C G Sbjct 402 VTCNNTRKEKMVCAVKMLKGNRNEKDVLDLLTEMDQMKRVGKHKNIINLLGVCTQNG--P 459 Query 974 LQLVMEYVPLGSLRDYLPRH----------------------------SIGLAQLLLFAQ 1005 L LV+EY G+LRDYL R+ ++ ++ FA Sbjct 460 LWLVIEYAAQGNLRDYLRRNRPQNTLCNLVLPSEGRNPDDELPVPHGDTLTQKDIVSFAF 519 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 Q+ G+ +L + IHRDLAARNVL+ + ++KI DFGLA+ + +YYR G P Sbjct 520 QVARGLEFLAQKKCIHRDLAARNVLVTEELVMKIADFGLARDIR-SCDYYRKHTRGHLPY 578 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 W A E + + F +A+DVWSFGV L+E+ + L G + L Sbjct 579 KWMALEAMSDNIFTHATDVWSFGVLLWEIFS--------------LAGSPYPGIKTHELV 624 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + L GERL +P E+Y LM++CWE + S RP F L+ L + Sbjct 625 KFLRSGERLDKPQYASQEMYRLMRDCWEEDPSKRPNFRTLVEDLDRM 671 Score = 226 bits (576), Expect = 1e-60, Method: Composition-based stats. Identities = 70/335 (21%), Positives = 127/335 (38%), Gaps = 63/335 (19%) Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 P N+ + +++IT + L +G V++ L + Sbjct 364 PFEFNIQLDLQWELQREDITLVERLDEGFFGQVFKADL------------------VTCN 405 Query 631 RDRGQELRVVLKVLDPSHHDI-ALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTE 688 R +++ +K+L + ++ L M +V H ++ + GVC + +V E Sbjct 406 NTRKEKMVCAVKMLKGNRNEKDVLDLLTEMDQMKRVGKHKNIINLLGVCTQNGPLWLVIE 465 Query 689 YVEHGPLDVWLRRERGHVPMAWK--------------------------MVVAQQLASAL 722 Y G L +LRR R + + A Q+A L Sbjct 466 YAAQGNLRDYLRRNRPQNTLCNLVLPSEGRNPDDELPVPHGDTLTQKDIVSFAFQVARGL 525 Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP- 777 +L K +H ++ RN+L+ + +K++D G+ R+ +P Sbjct 526 EFLAQKKCIHRDLAARNVLVTEELV-------MKIADFGLARDIRSCDYYRKHTRGHLPY 578 Query 778 -WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--P 834 W+A E + + A D W FG L EI +P E F + RL P Sbjct 579 KWMALEAMSDNI--FTHATDVWSFGVLLWEIFSLAGSPYPGIKTHELVKFLRSGERLDKP 636 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + ++ L C +P++RP+FRT++ DL R+ Sbjct 637 QYASQEMYRLMRDCWEEDPSKRPNFRTLVEDLDRM 671 >sp|P16056|MET_MOUSE Hepatocyte growth factor receptor OS=Mus musculus OX=10090 GN=Met PE=1 SV=1 Length=1379 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 93/286 (33%), Positives = 142/286 (50%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L + S + E I++ H Sbjct 1077 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHP 1135 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1136 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1194 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073 ++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L Sbjct 1195 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1253 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV L+EL+T + +T L +G R Sbjct 1254 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITIYLLQGRR 1299 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +P+ CP +Y +M CW +A RP+F L+ + ++ + G+ Sbjct 1300 LLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISSIFSTFIGE 1345 Score = 233 bits (593), Expect = 6e-61, Method: Composition-based stats. Identities = 64/328 (20%), Positives = 121/328 (37%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHH 649 +G+G VY G L G+++ +K L+ + Sbjct 1078 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1116 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1117 EEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1176 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1177 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1229 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1230 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1287 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1288 FDITIYLLQGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISSIFSTFIGEHY 1347 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D +G Sbjct 1348 VHVNATYVNVKCVAPYPSLLPSQDNIDG 1375 >sp|F4J0D2|PBL36_ARATH Serine/threonine-protein kinase PBL36 OS=Arabidopsis thaliana OX=3702 GN=PBL36 PE=1 SV=2 Length=476 Score = 258 bits (659), Expect = 3e-74, Method: Composition-based stats. Identities = 85/282 (30%), Positives = 127/282 (45%), Gaps = 16/282 (6%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LGEG FG V + P GTG VAVK L D G Q W EI+ L L H Sbjct 132 LGEGGFGCVFKGWIEENGTAPVKPGTGLTVAVKTLNPD-GLQGHKEWLAEINFLGNLVHP 190 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLH 1015 ++K G C ++ ++ LV E++P GSL ++L R + + + A +G+A+LH Sbjct 191 SLVKLVGYCMEEDQR--LLVYEFMPRGSLENHLFRRTLPLPWSVRMKIALGAAKGLAFLH 248 Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 + I+RD N+LLD + K+ DFGLAK P+ + + V + APE Sbjct 249 EEAEKPVIYRDFKTSNILLDGEYNAKLSDFGLAKDAPDEKKSH-VSTRVMGTYGYAAPEY 307 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQ-MTVLRLTELLER 1130 + SDV+SFGV L E+LT S +S P L+ + + R LL+ Sbjct 308 VMTGHLTTKSDVYSFGVVLLEILTGRRSVDKSRPNGEQNLVEWVRPHLLDKKRFYRLLDP 367 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 K + + C ++ RP ++ LK + Sbjct 368 RLEGHYSIKGAQKATQVAAQCLNRDSKARPKMSEVVEALKPL 409 Score = 249 bits (637), Expect = 3e-71, Method: Composition-based stats. Identities = 70/340 (21%), Positives = 125/340 (37%), Gaps = 51/340 (15%) Query 559 SNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618 S+ +M G L + + ++ + S LG+G V++G + G+ + Sbjct 96 SSTPLMSGELKYSSKLRIFMFNDLKLATRNFRPESLLGEGGFGCVFKGWIEENGTAPVKP 155 Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678 G L V +K L+P + + + + H L + G C+ Sbjct 156 ---------------GTGLTVAVKTLNPDGLQGHKEWLAEINFLGNLVHPSLVKLVGYCM 200 Query 679 RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNV 735 + ++V E++ G L+ L R +P + +M +A A L++L K +++ + Sbjct 201 EEDQRLLVYEFMPRGSLENHLFRRTLPLPWSVRMKIALGAAKGLAFLHEEAEKPVIYRDF 260 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGAN 789 NILL KLSD G+ A ++ + + APE + G Sbjct 261 KTSNILLD-------GEYNAKLSDFGLAKDAPDEKKSHVSTRVMGTYGYAAPEYVMTG-- 311 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ------RQHRLPEPSCPQL-- 841 L+T D + FG LLEI + +SR E+ + R P+L Sbjct 312 HLTTKSDVYSFGVVLLEILTGRRSVDKSRPNGEQNLVEWVRPHLLDKKRFYRLLDPRLEG 371 Query 842 ----------ATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 + +QCL + RP ++ L L Sbjct 372 HYSIKGAQKATQVAAQCLNRDSKARPKMSEVVEALKPLPN 411 >sp|O15146|MUSK_HUMAN Muscle, skeletal receptor tyrosine-protein kinase OS=Homo sapiens OX=9606 GN=MUSK PE=1 SV=1 Length=869 Score = 268 bits (685), Expect = 3e-74, Method: Composition-based stats. Identities = 87/336 (26%), Positives = 151/336 (45%), Gaps = 43/336 (13%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND-GTGEMVAV 929 N +P + + ++ +RD+GEG FG+V MVAV Sbjct 549 HPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAV 608 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K LK + ++ +++E ++ + +I+K G C K + L+ EY+ G L ++ Sbjct 609 KMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEF 666 Query 990 LPR-------------------------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDL 1024 L + A+ L A+Q+ GMAYL + ++HRDL Sbjct 667 LRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDL 726 Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084 A RN L+ + +VKI DFGL++ + +YY+ E+ P+ W PE + ++ SDV Sbjct 727 ATRNCLVGENMVVKIADFGLSRNIY-SADYYKANENDAIPIRWMPPESIFYNRYTTESDV 785 Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144 W++GV L+E+ ++ M + + G L P+ CP E+ Sbjct 786 WAYGVVLWEIFSYGLQ--------------PYYGMAHEEVIYYVRDGNILSCPENCPVEL 831 Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180 Y+LM+ CW + RP+F ++ IL+ + E+ +G Sbjct 832 YNLMRLCWSKLPADRPSFTSIHRILERMCERAEGTV 867 Score = 245 bits (625), Expect = 2e-66, Method: Composition-based stats. Identities = 71/317 (22%), Positives = 127/317 (40%), Gaps = 60/317 (19%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + I + +G+G V++ R +P V +K+L Sbjct 571 PRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTM-------------------VAVKML 611 Query 645 DPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--- 700 D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+ +LR Sbjct 612 KEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMS 671 Query 701 ------------------RERGHVPMA--WKMVVAQQLASALSYLENKNLVHGNVCGRNI 740 G P++ ++ +A+Q+A+ ++YL + VH ++ RN Sbjct 672 PHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNC 731 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLSTA 794 L+ G + +K++D G+ S + I W+ PE + N +T Sbjct 732 LV-------GENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIF--YNRYTTE 782 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYE 852 D W +G L EI G P + E ++ + + L PE +L L C + Sbjct 783 SDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKL 842 Query 853 PTQRPSFRTILRDLTRL 869 P RPSF +I R L R+ Sbjct 843 PADRPSFTSIHRILERM 859 >sp|Q7TPS0|KS6A6_MOUSE Ribosomal protein S6 kinase alpha-6 OS=Mus musculus OX=10090 GN=Rps6ka6 PE=1 SV=2 Length=764 Score = 266 bits (679), Expect = 3e-74, Method: Composition-based stats. Identities = 113/670 (17%), Positives = 217/670 (32%), Gaps = 113/670 (17%) Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 + P T ++ + + + D + L LGQG+ V+ R + P+ G++ L Sbjct 73 KEVPITQHVKE-GYEKADPAQFDLLKVLGQGSFGKVFLVRKKTG----PDAGQLYAMKVL 127 Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 LKV D + +H + +H + ++ Sbjct 128 RKAS---------LKVRDRVRTKMERDILVEV------NHPFIVKLHYAFQTEGKLYLIL 172 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 +++ G + L +E K +A +LA AL +L +V+ ++ NILL +G Sbjct 173 DFLRGGDVFTRLSKEVLFTEEDVKFYLA-ELALALDHLHRLGIVYRDLKPENILLDEIG- 230 Query 748 AEGTSPFIKLSDPGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 IKL+D G+ ++ +E++ + ++APE + A+ S + D W +G Sbjct 231 ------HIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRAH--SQSADWWSYGVL 282 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEP--------- 853 + E+ G P Q + +E + + +P+ + +L P Sbjct 283 MFEML-TGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPANRLGSEGV 341 Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG------- 906 + D F + K G Sbjct 342 EEVKRHAFFASIDWNKLYKREVQPPFRPASGKPDDTFCFDPEFTAKTPKDSPGLPASANA 401 Query 907 -----HFGKVS---LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE------IDILR 952 F V+ Y T + ++ + + + + +E + + Sbjct 402 HQLFKGFSFVATSIAEEYKITPVTSSNVLPIVQINGNAAQFSEAYELKEDIGIGSYSVCK 461 Query 953 TLYH--EHI---IKYKGCCEDQGEKSLQLVMEY------VPLGSLRD------------- 988 H ++ +K + + ++++M Y + L + D Sbjct 462 RCIHSASNVEFAVKIIDKNKRDPSEEIEILMRYGQHPNIISLKEVFDDGKYVYLVTDLMK 521 Query 989 -------YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL-LDNDRL---V 1037 L + + I + + LH+Q +HRDL N+L +D + Sbjct 522 GGELLDRILKKKCFSEQEASNVLYVITKTVECLHSQGVVHRDLKPSNILYMDESAHPDSI 581 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 KI DFG AK + + + APE L + + A D+WS GV LY +L Sbjct 582 KICDFGFAKQLRGENGLLLT---PCYTANFVAPEVLTQQGYDAACDIWSLGVLLYTMLAG 638 Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157 + P E I + G D L+ + + Sbjct 639 YTPFSNGPNDTPEEILLRIGNGRF---------SLSGGIWDNISRGAKDLLSHMLHMDPH 689 Query 1158 FRPTFENLIP 1167 R T E ++ Sbjct 690 QRYTAEQVLK 699 Score = 147 bits (370), Expect = 8e-35, Method: Composition-based stats. Identities = 45/268 (17%), Positives = 87/268 (32%), Gaps = 24/268 (9%) Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690 + +K++D + D + E ++ + H ++ + V G +VT+ + Sbjct 465 HSASNVEFAVKIIDKNKRDPS----EEIEILMRYGQHPNIISLKEVFDDGKYVYLVTDLM 520 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 + G L + +++ V + + L ++ +VH ++ NIL Sbjct 521 KGGELLDRILKKKC-FSEQEASNVLYVITKTVECLHSQGVVHRDLKPSNILYMDESAHPD 579 Query 751 TSPFIKLSDPGVGLGALSREERVERIPWL----APECLPGGANSLSTAMDKWGFGATLLE 806 + IK+ D G + + APE L A D W G L Sbjct 580 S---IKICDFGFAKQLRGENGLLLTPCYTANFVAPEVLTQ--QGYDAACDIWSLGVLLYT 634 Query 807 ICFDGEAPLQSRSPS--EKEHFYQRQHR------LPEPSCPQLATLTSQCLTYEPTQRPS 858 + G P + E+ R + + L S L +P QR + Sbjct 635 MLA-GYTPFSNGPNDTPEEILLRIGNGRFSLSGGIWDNISRGAKDLLSHMLHMDPHQRYT 693 Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPA 886 +L+ Q L + + P Sbjct 694 AEQVLKHPWITQREQLPRHQPNSDEPPQ 721 >sp|Q9LRY1|PBL25_ARATH Probable serine/threonine-protein kinase PBL25 OS=Arabidopsis thaliana OX=3702 GN=PBL25 PE=2 SV=1 Length=381 Score = 254 bits (650), Expect = 3e-74, Method: Composition-based stats. Identities = 82/285 (29%), Positives = 131/285 (46%), Gaps = 18/285 (6%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 ++ +GEG FG+V Y + ++VAVK L + G Q + + E+ +L L+ Sbjct 64 NFRQECLIGEGGFGRV----YKGKLENPAQVVAVKQLDRN-GLQGQREFLVEVLMLSLLH 118 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEG 1010 H +++ G C D ++ LV EY+PLGSL D+L + + + A +G Sbjct 119 HRNLVNLIGYCADGDQR--LLVYEYMPLGSLEDHLLDLEPGQKPLDWNTRIKIALGAAKG 176 Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH + I+RDL + N+LLD + + K+ DFGLAK P G + V + Sbjct 177 IEYLHDEADPPVIYRDLKSSNILLDPEYVAKLSDFGLAKLGPVGDTLH-VSSRVMGTYGY 235 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQG-QMTVLRLT 1125 APE + SDV+SFGV L EL++ + P+ L+ A R Sbjct 236 CAPEYQRTGYLTNKSDVYSFGVVLLELISGRRVIDTMRPSHEQNLVTWALPIFRDPTRYW 295 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +L + R P+K + + C E + RP ++I L Sbjct 296 QLADPLLRGDYPEKSLNQAIAVAAMCLHEEPTVRPLMSDVITALS 340 Score = 245 bits (626), Expect = 6e-71, Method: Composition-based stats. Identities = 74/407 (18%), Positives = 129/407 (32%), Gaps = 65/407 (16%) Query 531 AALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ--KE 588 + +L P T+ ++ + A + +F + K Sbjct 5 SCFSSKVLDNEGSSMPAPYKQPNSPKRTTGEVVAKNANGPSNNMGARIFTFRELATATKN 64 Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 Q +G+G VY+G+L V +K LD + Sbjct 65 FRQECLIGEGGFGRVYKGKLENPAQ------------------------VVAVKQLDRNG 100 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVP 707 F ++S + H +L + G C G + ++V EY+ G L+ L E G P Sbjct 101 LQGQREFLVEVLMLSLLHHRNLVNLIGYCADGDQRLLVYEYMPLGSLEDHLLDLEPGQKP 160 Query 708 MAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + W ++ +A A + YL ++ +++ ++ NILL +A KLSD G+ Sbjct 161 LDWNTRIKIALGAAKGIEYLHDEADPPVIYRDLKSSNILLDPEYVA-------KLSDFGL 213 Query 763 GLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 + + + APE G L+ D + FG LLE+ Sbjct 214 AKLGPVGDTLHVSSRVMGTYGYCAPEYQRTGY--LTNKSDVYSFGVVLLELISGRRVIDT 271 Query 817 SRSPSEKEHFYQRQH------RLPEPSCPQLA------------TLTSQCLTYEPTQRPS 858 R E+ R + + P L + + CL EPT RP Sbjct 272 MRPSHEQNLVTWALPIFRDPTRYWQLADPLLRGDYPEKSLNQAIAVAAMCLHEEPTVRPL 331 Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 ++ L+ L + + N Sbjct 332 MSDVITALSFLGASSNSSNTGSNHLQQNRSNKYQDAVQWDSSPRYAN 378 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens OX=9606 GN=PTK2 PE=1 SV=2 Length=1052 Score = 271 bits (692), Expect = 3e-74, Method: Composition-based stats. Identities = 100/301 (33%), Positives = 148/301 (49%), Gaps = 24/301 (8%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQH 940 P++ + ++ R +GEG FG V Y P N VA+K K Sbjct 407 YTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALA--VAIKTCKNCTSDSV 464 Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLA 998 R + QE +R H HI+K G E + ++ME LG LR +L ++S+ LA Sbjct 465 REKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLA 521 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 L+L+A Q+ +AYL ++ ++HRD+AARNVL+ ++ VK+GDFGL++ + + Y Sbjct 522 SLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKA 579 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 G P+ W APE + +F ASDVW FGV ++E+L H Sbjct 580 SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ--------------G 625 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 + + +E GERLP P CP +Y LM CW + S RP F L L T+ E+ + Sbjct 626 VKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKA 685 Query 1179 Q 1179 Q Sbjct 686 Q 686 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 69/305 (23%), Positives = 124/305 (41%), Gaps = 39/305 (13%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 T + + + ++ I +G+G +V++G + Sbjct 406 TYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQG---------------------IYMSP 444 Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 L V +K D F + A M Q H H+ + GV P ++ E Sbjct 445 ENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCT 503 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G L +L+ + + +A ++ A QL++AL+YLE+K VH ++ RN+L++ + Sbjct 504 LGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS-------S 556 Query 752 SPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 + +KL D G+ I W+APE + ++A D W FG + E Sbjct 557 NDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWE 614 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 I G P Q ++ + R +P P L +L ++C Y+P++RP F + Sbjct 615 ILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKA 674 Query 865 DLTRL 869 L+ + Sbjct 675 QLSTI 679 Score = 38.1 bits (87), Expect = 0.72, Method: Composition-based stats. Identities = 32/191 (17%), Positives = 67/191 (35%), Gaps = 25/191 (13%) Query 120 PAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHF 179 P ++ Q + D + + ++Q K +++ + + +E Sbjct 117 PEEWKYELRIRYLPKGFLNQFTE--DKPTLNFFYQQVKSDYM---LEIADQVDQEIALKL 171 Query 180 KNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNVFR 239 + ++ + AL E + K K P+S ++ + R ++ FR Sbjct 172 GCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTL--RKLIQQTFR 229 Query 240 RFLRDFQPGRLSQQMVMVKYLATLERLAP--RFGTERVP-------VCHLRLLAQAEGEP 290 +F L+++ ++K+ E L+P RF E + + L E Sbjct 230 QF------ANLNREESILKF---FEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGI 280 Query 291 CYIRDSGVAPT 301 Y+ D G PT Sbjct 281 SYLTDKGCNPT 291 >sp|P21709|EPHA1_HUMAN Ephrin type-A receptor 1 OS=Homo sapiens OX=9606 GN=EPHA1 PE=1 SV=4 Length=976 Score = 270 bits (689), Expect = 3e-74, Method: Composition-based stats. Identities = 90/307 (29%), Positives = 141/307 (46%), Gaps = 20/307 (7%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 L+P+ +L +GEG FG+V + + V Sbjct 595 WLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDC-KTV 653 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK + +E I+ H HI+ +G + K + ++ E++ G+L Sbjct 654 AIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKR--KPIMIITEFMENGALD 711 Query 988 DYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L L QL+ Q I GM YL +Y+HRDLAARN+L++ + K+ DFGL Sbjct 712 AFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLT 771 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + Y + G P+ W APE + F ASDVWSFG+ ++E+L+ D Sbjct 772 RLLDDFDGTYET-QGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDK----- 825 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 G+M+ + + +E G RLP P CP +Y LMKNCW + + RP F+ L Sbjct 826 ---------PYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKL 876 Query 1166 IPILKTV 1172 L+ + Sbjct 877 QAHLEQL 883 Score = 258 bits (658), Expect = 5e-70, Method: Composition-based stats. Identities = 79/315 (25%), Positives = 127/315 (40%), Gaps = 39/315 (12%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 +D + + +G+G VY G LR+ V Sbjct 616 TRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCK---------------------TVA 654 Query 641 LKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +K L + F A++M Q SH H+ + GV + +++TE++E+G LD +L Sbjct 655 IKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFL 714 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R + + + Q +AS ++YL N N VH ++ RNIL+ + + K+SD Sbjct 715 REREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQ-------NLCCKVSD 767 Query 760 PGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ G + I W APE + +TA D W FG + E+ G+ Sbjct 768 FGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRI--FTTASDVWSFGIVMWEVLSFGDK 825 Query 814 PLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S E + +RLP P CP L L C Y+ +RP F+ + L +L Sbjct 826 PYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLA 885 Query 872 HNLADVLTVNPDSPA 886 + + N D Sbjct 886 NPHSLRTIANFDPRM 900 >sp|Q09YN5|MET_RABIT Hepatocyte growth factor receptor OS=Oryctolagus cuniculus OX=9986 GN=MET PE=3 SV=1 Length=1382 Score = 273 bits (699), Expect = 4e-74, Method: Composition-based stats. Identities = 94/286 (33%), Positives = 141/286 (49%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1080 HFSEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073 ++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1256 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV L+EL+T + +T L +G R Sbjct 1257 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1302 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +P+ CP +Y +M CW +A RP+F L+ + T+ + G+ Sbjct 1303 LLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISTIFSTFIGE 1348 Score = 230 bits (587), Expect = 3e-60, Method: Composition-based stats. Identities = 64/329 (19%), Positives = 120/329 (36%), Gaps = 42/329 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1081 FSEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1119 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1291 FDITVYLLQGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSFSELVSRISTIFSTFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 + + V L +D +G Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNVDGT 1379 >sp|P70600|FAK2_RAT Protein-tyrosine kinase 2-beta OS=Rattus norvegicus OX=10116 GN=Ptk2b PE=1 SV=1 Length=1009 Score = 270 bits (690), Expect = 4e-74, Method: Composition-based stats. Identities = 97/278 (35%), Positives = 149/278 (54%), Gaps = 22/278 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG+V Y + G VAVK K DC ++ + E I++ L H HI+K Sbjct 431 LGEGFFGEVYEGVYTN-HKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKL 489 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G E E+ +VME P G L YL R+ S+ + L+L+A QIC+ MAYL + + + Sbjct 490 IGIIE---EEPTWIVMELYPYGELGHYLERNKNSLKVPTLVLYALQICKAMAYLESINCV 546 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+A RN+L+ + VK+GDFGL++ + E +YY+ P+ W +PE + +F Sbjct 547 HRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKASVT-RLPIKWMSPESINFRRFTT 604 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ASDVW F V ++E+L+ + + +LE+G+RLP+P+ C Sbjct 605 ASDVWMFAVCMWEILSFGKQ--------------PFFWLENKDVIGVLEKGDRLPKPELC 650 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P +Y LM CW+ + S RP F L+ L +++ + Sbjct 651 PPVLYTLMTRCWDYDPSDRPRFTELVCSLSDIYQMERD 688 Score = 247 bits (631), Expect = 2e-66, Method: Composition-based stats. Identities = 75/331 (23%), Positives = 132/331 (40%), Gaps = 39/331 (12%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 A TL + V ++++ LG+G VYEG Sbjct 403 AEIPDETLRRPGGPQYGVAREDVVLNRILGEGFFGEVYEG-------------------- 442 Query 627 LVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 V +G+++ V +K D F A +M + H H+ + G+ + + Sbjct 443 -VYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWI 500 Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 V E +G L +L R + + + ++ A Q+ A++YLE+ N VH ++ RNIL+A Sbjct 501 VMELYPYGELGHYLERNKNSLKVPTLVLYALQICKAMAYLESINCVHRDIAVRNILVA-- 558 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGF 800 + +KL D G+ + I W++PE + +TA D W F Sbjct 559 -----SPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESI--NFRRFTTASDVWMF 611 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPS 858 + EI G+ P + ++ RLP+P P L TL ++C Y+P+ RP Sbjct 612 AVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDYDPSDRPR 671 Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 F ++ L+ + + ++ P Sbjct 672 FTELVCSLSDIYQMERDIAIEQERNARYRPP 702 >sp|Q5UQG7|YR818_MIMIV Putative serine/threonine-protein kinase/receptor R818 OS=Acanthamoeba polyphaga mimivirus OX=212035 GN=MIMI_R818 PE=3 SV=1 Length=1651 Score = 274 bits (701), Expect = 4e-74, Method: Composition-based stats. Identities = 75/286 (26%), Positives = 124/286 (43%), Gaps = 31/286 (11%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEI 948 + + ++ + +G G +G V++ + N VAVK +K + ++ EI Sbjct 1387 WIINYDDIQIGKQIGVGSYGIVNMGKWKNIN------VAVKKFVKQKIDEKQMLEFRAEI 1440 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008 L L H HII G C + ++ +V E++ GSLR+ + + Q Sbjct 1441 AFLSQLRHPHIILMIGACLKR--PNICIVTEFMGNGSLRNVIKTTKPEWKLKIKMLYQTA 1498 Query 1009 EGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G+ YLH IHRD+ N+L+D+ VKI DFG A+ E R Sbjct 1499 LGIGYLHNSDPIIIHRDIKPSNILVDDSMNVKIADFGFARIKEENSVMTR-----CGTPC 1553 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE ++ K+ DV+SFG+ ++E+LT + ++++ Sbjct 1554 WTAPEIIRGEKYTEKVDVFSFGIVMWEVLTCKEPF---------------SGCNFMKVSM 1598 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + G R P CP + LMK CW + RP+ E++I L + Sbjct 1599 DILEGARPQIPSDCPIDFTKLMKQCWHAKPDKRPSMEDVIMGLNDM 1644 Score = 243 bits (620), Expect = 4e-64, Method: Composition-based stats. Identities = 79/296 (27%), Positives = 128/296 (43%), Gaps = 24/296 (8%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHR 941 D L + LG G G+V + G VAVK L ++ Sbjct 779 HQRVEDEWEVDFHELDFMESLGSGGSGEVFKAMWK------GTEVAVKKLVNSNITKDAE 832 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLA 998 +KQEI + +L H +++ + ++ +VME++ LGSL D L I Sbjct 833 RNFKQEIHRMTSLRHPNVVLFMAASTRP--PNMCIVMEFMSLGSLYDLLGNELVTEIPPV 890 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 + A Q +GM +LH+ +HRDL + N+LLD+ VK+ DFGL K + Sbjct 891 LRIRIAYQAAKGMHFLHSSDIVHRDLKSLNLLLDSKWNVKVSDFGLTKIKDNNKGKSSTK 950 Query 1059 EDGDSPVFWYAPECLKEYK--FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 ED + W APE L E + Y +DV+SFG+ ++EL+T IG++ Sbjct 951 EDSVCSIQWTAPEVLSEKQDIDYILADVYSFGIIMWELMTRLRP----------YIGLSP 1000 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + V + + L + + + L+ CW + RP+F ++ L T+ Sbjct 1001 AAIAVAVIRDNLRPEIQEEDINLMSSDYVELVNICWHKDTMIRPSFLEIMTKLSTL 1056 Score = 231 bits (589), Expect = 3e-60, Method: Composition-based stats. Identities = 61/320 (19%), Positives = 119/320 (37%), Gaps = 46/320 (14%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 ++N I+ G + L+ + L ++ +I +G G+ V G+ + Sbjct 1363 STNGILYGGIKQENEYLSSAGLCRWIINYDDIQIGKQIGVGSYGIVNMGKWKN------- 1415 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHG 675 + V +K L F + +SQ+ H H+ + G Sbjct 1416 -------------------INVAVKKFVKQKIDEKQMLEFRAEIAFLSQLRHPHIILMIG 1456 Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHG 733 C++ P +VTE++ +G L ++ + K+ + Q A + YL N + ++H Sbjct 1457 ACLKRPNICIVTEFMGNGSLRNVIKTTKPE--WKLKIKMLYQTALGIGYLHNSDPIIIHR 1514 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE--ERVERIPWLAPECLPGGANSL 791 ++ NIL+ S +K++D G R W APE + G Sbjct 1515 DIKPSNILVD-------DSMNVKIADFGFARIKEENSVMTRCGTPCWTAPEIIRG--EKY 1565 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEK--EHFYQRQHRLPEPSCPQLATLTSQCL 849 + +D + FG + E+ E P + + + + ++P L QC Sbjct 1566 TEKVDVFSFGIVMWEVLTCKE-PFSGCNFMKVSMDILEGARPQIPSDCPIDFTKLMKQCW 1624 Query 850 TYEPTQRPSFRTILRDLTRL 869 +P +RPS ++ L + Sbjct 1625 HAKPDKRPSMEDVIMGLNDM 1644 Score = 217 bits (552), Expect = 7e-56, Method: Composition-based stats. Identities = 70/352 (20%), Positives = 117/352 (33%), Gaps = 51/352 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 VD E+ + LG G V++ + G E+ V Sbjct 786 WEVDFHELDFMESLGSGGSGEVFKAMWK------------------------GTEVAVKK 821 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 V D F + M+ + H ++ R P +V E++ G L L Sbjct 822 LVNSNITKDAERNFKQEIHRMTSLRHPNVVLFMAASTRPPNMCIVMEFMSLGSLYDLLGN 881 Query 702 E-RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 E +P ++ +A Q A + +L + ++VH ++ N+LL +K+SD Sbjct 882 ELVTEIPPVLRIRIAYQAAKGMHFLHSSDIVHRDLKSLNLLLDSK-------WNVKVSDF 934 Query 761 GVGL-------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ + ++E+ V I W APE L + D + FG + E+ Sbjct 935 GLTKIKDNNKGKSSTKEDSVCSIQWTAPEVLSEKQDIDYILADVYSFGIIMWELMTR-LR 993 Query 814 PLQSRSPSEKEHFYQRQHRLPEP-------SCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 P SP+ R + PE L + C + RPSF I+ L Sbjct 994 PYIGLSPAAIAVAVIRDNLRPEIQEEDINLMSSDYVELVNICWHKDTMIRPSFLEIMTKL 1053 Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHK----RYLKKIRDLGEGHFGKVSLY 914 + L + T S S + D + FG + Sbjct 1054 STLIGGSGITTGTSTSSSNQSSDYIGPNIITRTKNIHNNDETKNSFGSTTYG 1105 >sp|P35546|RET_MOUSE Proto-oncogene tyrosine-protein kinase receptor Ret OS=Mus musculus OX=10090 GN=Ret PE=1 SV=2 Length=1115 Score = 271 bits (694), Expect = 4e-74, Method: Composition-based stats. Identities = 105/320 (33%), Positives = 145/320 (45%), Gaps = 43/320 (13%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYC-YDPTNDGTGEMVAVKALKADCGPQHRSG 943 P F ++ L + LGEG FGKV + VAVK LK + Sbjct 713 PEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASQSELRD 772 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------------ 991 E ++L+ + H H+IK G C G L L++EY GSLR +L Sbjct 773 LLSEFNLLKQVNHPHVIKLYGACSQDG--PLLLIVEYAKYGSLRGFLRDSRKIGPAYVSG 830 Query 992 -------------RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 + + L+ FA QI GM YL +HRDLAARN+L+ R +K Sbjct 831 GGSRNSSSLDHPDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMK 890 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 I DFGL++ V E Y + + G PV W A E L ++ + SDVWSFGV L+E++T Sbjct 891 ISDFGLSRDVYEEDSYVK-KSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVT-- 947 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 L G + RL LL+ G R+ RPD C E+Y LM CW+ E Sbjct 948 ------------LGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDK 995 Query 1159 RPTFENLIPILKTVHEKYQG 1178 RP F ++ L+ + K + Sbjct 996 RPVFADISKDLEKMMVKSRD 1015 Score = 242 bits (617), Expect = 3e-64, Method: Composition-based stats. Identities = 70/330 (21%), Positives = 122/330 (37%), Gaps = 60/330 (18%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 + + + +K + LG+G V + + Sbjct 709 SFKIPEDPKWEFPRKNLVLGKTLGEGEFGKVVKA-------------------TAFRLKG 749 Query 633 RGQELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 R V +K+L + +L+ QV+H H+ ++G C + +++ EY + Sbjct 750 RAGYTTVAVKMLKENASQSELRDLLSEFNLLKQVNHPHVIKLYGACSQDGPLLLIVEYAK 809 Query 692 HGPLDVWLRRERG-----------------------HVPMAWKMVVAQQLASALSYLENK 728 +G L +LR R + M + A Q++ + YL Sbjct 810 YGSLRGFLRDSRKIGPAYVSGGGSRNSSSLDHPDERVLTMGDLISFAWQISRGMQYLAEM 869 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPE 782 LVH ++ RNIL+A +K+SD G+ + V++ + W+A E Sbjct 870 KLVHRDLAARNILVAE-------GRKMKISDFGLSRDVYEEDSYVKKSKGRIPVKWMAIE 922 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQ 840 L + +T D W FG L EI G P P + + HR+ P+ + Sbjct 923 SLFD--HIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEE 980 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + L QC EP +RP F I +DL ++ Sbjct 981 MYRLMLQCWKQEPDKRPVFADISKDLEKMM 1010 >sp|Q9SY91|PBL15_ARATH Probable serine/threonine-protein kinase PBL15 OS=Arabidopsis thaliana OX=3702 GN=PBL15 PE=1 SV=1 Length=424 Score = 255 bits (652), Expect = 5e-74, Method: Composition-based stats. Identities = 86/279 (31%), Positives = 130/279 (47%), Gaps = 13/279 (5%) Query 903 LGEGHFGKVSLYCYD--PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LGEG FGKV D + VAVK L + HR W E+ L L H +++ Sbjct 105 LGEGGFGKVYKGYVDDYLRQSLKAQPVAVKLLDIEGLQGHRE-WLSEVIFLGQLKHPNLV 163 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLH-- 1015 K G C ++ E+ L+ E++P GSL ++L R S+ A L A +G+A+LH Sbjct 164 KLIGYCCEEEER--VLIYEFMPRGSLENHLFRRISLSLPWATRLKIAVAAAKGLAFLHDL 221 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 I+RD N+LLD+D K+ DFGLAK PEG + + V + APE + Sbjct 222 ESPIIYRDFKTSNILLDSDFTAKLSDFGLAKMGPEGSKSH-VTTRVMGTYGYAAPEYVST 280 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMT-VLRLTELLERGER 1133 SDV+S+GV L ELLT +++ S P +I ++ +T RL +++ Sbjct 281 GHLTTKSDVYSYGVVLLELLTGRRATEKSRPKNQQNIIDWSKPYLTSSRRLRCVMDPRLA 340 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 K + L C RP ++ L+++ Sbjct 341 GQYSVKAAKDTALLALQCVSPNPKDRPKMLAVVEALESL 379 Score = 229 bits (583), Expect = 1e-64, Method: Composition-based stats. Identities = 66/330 (20%), Positives = 119/330 (36%), Gaps = 54/330 (16%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L Q+ ++ + + LG+G VY+G + R Sbjct 83 DLVDFQMCELKMITQSFSGNYLLGEGGFGKVYKGYV------------------DDYLRQ 124 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 + V +K+LD + + Q+ H +L + G C E +++ E++ Sbjct 125 SLKAQPVAVKLLDIEGLQGHREWLSEVIFLGQLKHPNLVKLIGYCCEEEERVLIYEFMPR 184 Query 693 GPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLAE 749 G L+ L R +P A ++ +A A L++L +++ + NILL Sbjct 185 GSLENHLFRRISLSLPWATRLKIAVAAAKGLAFLHDLESPIIYRDFKTSNILLD------ 238 Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 + KLSD G+ + + + APE + G L+T D + +G Sbjct 239 -SDFTAKLSDFGLAKMGPEGSKSHVTTRVMGTYGYAAPEYVSTG--HLTTKSDVYSYGVV 295 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQ------HRLPEPSCPQL------------ATLT 845 LLE+ A +SR +++ + RL P+L A L Sbjct 296 LLELLTGRRATEKSRPKNQQNIIDWSKPYLTSSRRLRCVMDPRLAGQYSVKAAKDTALLA 355 Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 QC++ P RP ++ L L + Sbjct 356 LQCVSPNPKDRPKMLAVVEALESLIHYKDM 385 >sp|Q7T6Y2|YR831_MIMIV Putative serine/threonine-protein kinase/receptor R831 OS=Acanthamoeba polyphaga mimivirus OX=212035 GN=MIMI_R831 PE=3 SV=2 Length=1624 Score = 274 bits (700), Expect = 5e-74, Method: Composition-based stats. Identities = 76/314 (24%), Positives = 130/314 (41%), Gaps = 33/314 (11%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 + D S + + + + +G G +G V + + VA Sbjct 1336 IDYMADIDKEDSFLTSANMCRWIINYDEISIGKQIGLGSYGIVFNGKWKGVD------VA 1389 Query 929 VKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 VK +K ++ E+ L L H +I+ + G C + ++ +V EY+ +G+LR Sbjct 1390 VKKFVKQKLSETQLLEFRAEMAFLSELKHSNIVTFIGACIKK--PNICIVTEYMRMGNLR 1447 Query 988 DYLPRH--SIGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFG 1043 D L I A L G+ YLH+ + +HRD+ N+L+D VKI DFG Sbjct 1448 DVLKNPDIKITFANKLKLLYGAAMGIDYLHSSNPMIVHRDIKPANILVDEHFNVKIADFG 1507 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 A+ + W APE ++ K+ +DV+SFGV ++E+LT + Sbjct 1508 FARIKEDN-----TTMTRCGTPCWTAPEVIRGEKYCEKADVFSFGVVMWEVLTGKEPF-- 1560 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163 + ++++ + G R P CP E L+K CW +A RPT Sbjct 1561 -------------AECNFMKVSLDILEGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTMT 1607 Query 1164 NLIPILKTVHEKYQ 1177 ++ L + E++ Sbjct 1608 EVVQQLMLITEQFD 1621 Score = 247 bits (631), Expect = 1e-65, Method: Composition-based stats. Identities = 80/320 (25%), Positives = 134/320 (42%), Gaps = 33/320 (10%) Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922 L + + + + ++ L+ LG G +G+V + Sbjct 752 CIFGLLLLTLLIVIIFLLKHRNTTNNDWEIDFSELEIGETLGTGGYGEVYKSIWK----- 806 Query 923 TGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 G VAVK + + +E+ I+ +L H +++ + ++ +VME++ Sbjct 807 -GTEVAVKLISSKHVSKDMERSFFEEVKIMTSLRHPNVVLFMAA--STKSPNMCIVMEFM 863 Query 982 PLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 LGSL D L I A + A Q +GM +LH+ +HRDL + N+LLD+ VK Sbjct 864 SLGSLYDLLGNELIPEIPYALKIKMAYQASKGMHFLHSSGIVHRDLKSLNLLLDSKWNVK 923 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK--FYYASDVWSFGVTLYELLT 1096 + DFGL K V + + ++ + W APE L + Y +DV+SFG+ L+ELLT Sbjct 924 VSDFGLTK-VKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSFGIILWELLT 982 Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC----PCEVYHLMKNCW 1152 +G ++ G R P D+ E L+K CW Sbjct 983 REQPY--------------KGMTPAAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQCW 1028 Query 1153 ETEASFRPTFENLIPILKTV 1172 ++ RPTF ++ L + Sbjct 1029 HSDTIIRPTFLEIMTRLSNI 1048 Score = 230 bits (586), Expect = 6e-60, Method: Composition-based stats. Identities = 56/309 (18%), Positives = 107/309 (35%), Gaps = 42/309 (14%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L + + ++ EI+ +G G+ V+ G+ + Sbjct 1349 LTSANMCRWIINYDEISIGKQIGLGSYGIVFNGKWKG----------------------- 1385 Query 634 GQELRVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 + V +K L F + +S++ H+++ G C++ P +VTEY+ Sbjct 1386 ---VDVAVKKFVKQKLSETQLLEFRAEMAFLSELKHSNIVTFIGACIKKPNICIVTEYMR 1442 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAE 749 G L L+ + A K+ + A + YL + N +VH ++ NIL+ Sbjct 1443 MGNLRDVLKNPDIKITFANKLKLLYGAAMGIDYLHSSNPMIVHRDIKPANILVDE----- 1497 Query 750 GTSPFIKLSDPGVGLGALSRE--ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K++D G R W APE + G D + FG + E+ Sbjct 1498 --HFNVKIADFGFARIKEDNTTMTRCGTPCWTAPEVIRG--EKYCEKADVFSFGVVMWEV 1553 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDL 866 E + + + CP A L +C + +RP+ +++ L Sbjct 1554 LTGKEPFAECNFMKVSLDILEGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTMTEVVQQL 1613 Query 867 TRLQPHNLA 875 + Sbjct 1614 MLITEQFDH 1622 Score = 226 bits (575), Expect = 1e-58, Method: Composition-based stats. Identities = 62/304 (20%), Positives = 110/304 (36%), Gaps = 50/304 (16%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D E+ LG G VY+ + V + Sbjct 779 WEIDFSELEIGETLGTGGYGEVYKSIWKG--------------------------TEVAV 812 Query 642 KVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 K++ H D+ +F+E +M+ + H ++ + P +V E++ G L L Sbjct 813 KLISSKHVSKDMERSFFEEVKIMTSLRHPNVVLFMAASTKSPNMCIVMEFMSLGSLYDLL 872 Query 700 RRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 E +P A K+ +A Q + + +L + +VH ++ N+LL +K+S Sbjct 873 GNELIPEIPYALKIKMAYQASKGMHFLHSSGIVHRDLKSLNLLLDSK-------WNVKVS 925 Query 759 DPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 D G+ + + + I W+APE L D + FG L E+ E Sbjct 926 DFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSFGIILWELLTR-E 984 Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLA-------TLTSQCLTYEPTQRPSFRTILRD 865 P + +P+ R P S + L QC + RP+F I+ Sbjct 985 QPYKGMTPAAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQCWHSDTIIRPTFLEIMTR 1044 Query 866 LTRL 869 L+ + Sbjct 1045 LSNI 1048 >sp|Q2QLH6|MET_OTOGA Hepatocyte growth factor receptor OS=Otolemur garnettii OX=30611 GN=MET PE=3 SV=1 Length=1382 Score = 273 bits (698), Expect = 5e-74, Method: Composition-based stats. Identities = 90/285 (32%), Positives = 138/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD + VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1198 SKKFVHRDLAARNCMLDENFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348 Score = 231 bits (589), Expect = 1e-60, Method: Composition-based stats. Identities = 64/328 (20%), Positives = 121/328 (37%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1119 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L + +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------NFTVKVADFGLARDMYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D +G Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNIDG 1378 >sp|P18106|FER_DROME Tyrosine-protein kinase Fer OS=Drosophila melanogaster OX=7227 GN=FER PE=1 SV=3 Length=1325 Score = 273 bits (697), Expect = 6e-74, Method: Composition-based stats. Identities = 88/432 (20%), Positives = 157/432 (36%), Gaps = 80/432 (19%) Query 447 IRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYR-LILTVAQRSQAPDGMQSLRLRKF 505 + HG L V +L DG +L+ + + ++L+V + F Sbjct 957 EEEWFHGVLPREEVV-RLLNNDGDFLVRETIRNEESQIVLSVCWNGH----------KHF 1005 Query 506 PIEQQ-DGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 ++ +G F EG F S++EL L P + I+ Sbjct 1006 IVQTTGEGNFRFEG--PPFASIQELIMHQYHSEL----------------PVTVKSGAIL 1047 Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 R R + ++ L +G+G +VY+ +L+ Sbjct 1048 RRPVCRER---------WELSNDDVVLLERIGRGNFGDVYKAKLK--------------- 1083 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 +L V +K + D F + ++ Q H ++ + G+CV+ Sbjct 1084 ---------STKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPI 1134 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 ++V E V G L +LR+ + +M + + A+ + YLE+KN +H ++ RN L+ Sbjct 1135 MIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVD 1194 Query 744 RLGLAEGTSPFIKLSDPGVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 +K+SD G+ +S + + W APE L G ++ D W Sbjct 1195 -------LEHSVKISDFGMSREEEEYIVSDGMKQIPVKWTAPEALNFG--KYTSLCDVWS 1245 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ--LATLTSQCLTYEPTQRP 857 +G + EI G+ P + S +R+P P + L QC + RP Sbjct 1246 YGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRP 1305 Query 858 SFRTILRDLTRL 869 F I + L Sbjct 1306 HFDEIYNVVDAL 1317 Score = 270 bits (689), Expect = 6e-73, Method: Composition-based stats. Identities = 92/326 (28%), Positives = 144/326 (44%), Gaps = 25/326 (8%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 +E S + ++ + + + + + +G G+F Sbjct 1015 FRFEGPPFASIQELIMHQYHSELPVTVKSGAILRRPVCRERWELSNDDVVLLERIGRGNF 1074 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968 G V Y T VAVK + + + + QE IL+ H +I+K G C Sbjct 1075 GDV----YKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQ 1130 Query 969 QGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQL--LLFAQQICEGMAYLHAQHYIHRDLAA 1026 + + + +VME V GSL YL ++S GL + + GM YL +++ IHRDLAA Sbjct 1131 K--QPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAA 1188 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RN L+D + VKI DFG+++ E EY PV W APE L K+ DVWS Sbjct 1189 RNCLVDLEHSVKISDFGMSR---EEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWS 1245 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 +G+ ++E+ + D+ MT R E ++ G R+P P P E+Y Sbjct 1246 YGILMWEIFSKGDT--------------PYSGMTNSRARERIDTGYRMPTPKSTPEEMYR 1291 Query 1147 LMKNCWETEASFRPTFENLIPILKTV 1172 LM CW +A RP F+ + ++ + Sbjct 1292 LMLQCWAADAESRPHFDEIYNVVDAL 1317 >sp|Q9SFX0|PBL22_ARATH Probable serine/threonine-protein kinase PBL22 OS=Arabidopsis thaliana OX=3702 GN=PBL22 PE=2 SV=1 Length=381 Score = 253 bits (647), Expect = 7e-74, Method: Composition-based stats. Identities = 77/286 (27%), Positives = 131/286 (46%), Gaps = 19/286 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FG V D +G++VA+K L D G Q + E+ +L +H +++ Sbjct 81 IGKGGFGSVYKGRLD-----SGQVVAIKQLNPD-GHQGNQEFIVEVCMLSVFHHPNLVTL 134 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLH-- 1015 G C ++ LV EY+P+GSL D+L + + + A G+ YLH Sbjct 135 IGYCTSGAQR--LLVYEYMPMGSLEDHLFDLEPDQTPLSWYTRMKIAVGAARGIEYLHCK 192 Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 + I+RDL + N+LLD + VK+ DFGLAK P G+ + V + APE Sbjct 193 ISPSVIYRDLKSANILLDKEFSVKLSDFGLAKVGPVGNRTH-VSTRVMGTYGYCAPEYAM 251 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQM-TVLRLTELLERGE 1132 + SD++SFGV L EL++ + S P L+ A+ + + L++ Sbjct 252 SGRLTIKSDIYSFGVVLLELISGRKAIDLSKPNGEQYLVAWARPYLKDPKKFGLLVDPLL 311 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 R +C + + C EA+ RP +++ + + + + Sbjct 312 RGKFSKRCLNYAISITEMCLNDEANHRPKIGDVVVAFEYIASQSKS 357 Score = 239 bits (611), Expect = 6e-69, Method: Composition-based stats. Identities = 74/350 (21%), Positives = 129/350 (37%), Gaps = 67/350 (19%) Query 553 PQPGETSNLIIMRGARASPRTLN-LSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLR 609 P+ + + I++ G SP+ +F + K + + +G+G +VY+GRL Sbjct 36 PRGTGSKSGILVNGKVNSPKPGGGARSFTFKELAAATKNFREGNIIGKGGFGSVYKGRL- 94 Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTH 669 D GQ V +K L+P H F ++S H + Sbjct 95 ----------------------DSGQ--VVAIKQLNPDGHQGNQEFIVEVCMLSVFHHPN 130 Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYLE 726 L + G C G + ++V EY+ G L+ L E P++W +M +A A + YL Sbjct 131 LVTLIGYCTSGAQRLLVYEYMPMGSLEDHLFDLEPDQTPLSWYTRMKIAVGAARGIEYLH 190 Query 727 ---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIP 777 + ++++ ++ NILL + +KLSD G+ + Sbjct 191 CKISPSVIYRDLKSANILLDKE-------FSVKLSDFGLAKVGPVGNRTHVSTRVMGTYG 243 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP- 836 + APE G L+ D + FG LLE+ +A S+ E+ + L +P Sbjct 244 YCAPEYAMSG--RLTIKSDIYSFGVVLLELISGRKAIDLSKPNGEQYLVAWARPYLKDPK 301 Query 837 -----------------SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 ++T CL E RP ++ + Sbjct 302 KFGLLVDPLLRGKFSKRCLNYAISITEMCLNDEANHRPKIGDVVVAFEYI 351 >sp|Q2IBC0|MET_RHIFE Hepatocyte growth factor receptor OS=Rhinolophus ferrumequinum OX=59479 GN=MET PE=3 SV=1 Length=1381 Score = 273 bits (697), Expect = 7e-74, Method: Composition-based stats. Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V ND AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073 ++ ++HRDLAARN +LD + VK+ DFGLA+ V + EYY V + PV W A E L Sbjct 1197 SKKFVHRDLAARNCMLDENFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESL 1255 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV L+EL+T + +T L +G R Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1302 LLQPEYCPDHLYEVMLKCWHPKAEQRPSFAELVSRISAIFSAFIGE 1347 Score = 231 bits (589), Expect = 2e-60, Method: Composition-based stats. Identities = 64/328 (20%), Positives = 121/328 (37%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L +++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L + +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------NFTVKVADFGLARDVYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + QRPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDHLYEVMLKCWHPKAEQRPSFAELVSRISAIFSAFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D +G Sbjct 1350 VHVNATYVNVKCVAPYPCLLSSQDHVDG 1377 >sp|Q9QVP9|FAK2_MOUSE Protein-tyrosine kinase 2-beta OS=Mus musculus OX=10090 GN=Ptk2b PE=1 SV=2 Length=1009 Score = 270 bits (689), Expect = 7e-74, Method: Composition-based stats. Identities = 95/278 (34%), Positives = 148/278 (53%), Gaps = 22/278 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG+V Y + G VAVK K DC ++ + E I++ L H HI+K Sbjct 431 LGEGFFGEVYEGVYTN-HKGEKINVAVKTCKKDCTQDNKEKFMSEAVIMKNLDHPHIVKL 489 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G E E+ ++ME P G L YL R+ S+ + L+L+ QIC+ MAYL + + + Sbjct 490 IGIIE---EEPTWIIMELYPYGELGHYLERNKNSLKVPTLVLYTLQICKAMAYLESINCV 546 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+A RN+L+ + VK+GDFGL++ + E +YY+ P+ W +PE + +F Sbjct 547 HRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKASVT-RLPIKWMSPESINFRRFTT 604 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ASDVW F V ++E+L+ + + +LE+G+RLP+P+ C Sbjct 605 ASDVWMFAVCMWEILSFGKQ--------------PFFWLENKDVIGVLEKGDRLPKPELC 650 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P +Y LM CW+ + S RP F L+ L +++ + Sbjct 651 PPVLYTLMTRCWDYDPSDRPRFTELVCSLSDIYQMEKD 688 Score = 246 bits (627), Expect = 6e-66, Method: Composition-based stats. Identities = 74/331 (22%), Positives = 131/331 (40%), Gaps = 39/331 (12%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 A TL + V ++E+ LG+G VYEG Sbjct 403 AEIPDETLRRPGGPQYGVAREEVVLNRILGEGFFGEVYEG-------------------- 442 Query 627 LVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 V +G+++ V +K D F A +M + H H+ + G+ + + Sbjct 443 -VYTNHKGEKINVAVKTCKKDCTQDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWI 500 Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 + E +G L +L R + + + ++ Q+ A++YLE+ N VH ++ RNIL+A Sbjct 501 IMELYPYGELGHYLERNKNSLKVPTLVLYTLQICKAMAYLESINCVHRDIAVRNILVA-- 558 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGF 800 + +KL D G+ + I W++PE + +TA D W F Sbjct 559 -----SPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESI--NFRRFTTASDVWMF 611 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPS 858 + EI G+ P + ++ RLP+P P L TL ++C Y+P+ RP Sbjct 612 AVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPELCPPVLYTLMTRCWDYDPSDRPR 671 Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 F ++ L+ + + ++ P Sbjct 672 FTELVCSLSDIYQMEKDIAIEQERNARYRPP 702 >sp|Q9VBW3|CAD96_DROME Tyrosine kinase receptor Cad96Ca OS=Drosophila melanogaster OX=7227 GN=Cad96Ca PE=2 SV=2 Length=773 Score = 265 bits (677), Expect = 7e-74, Method: Composition-based stats. Identities = 91/301 (30%), Positives = 141/301 (47%), Gaps = 33/301 (11%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG-EMVAVKALKADCGPQHRSGWKQ 946 D F + LK LGEG FG+V N G VAVK LK R Sbjct 461 DRWEFPRYRLKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLS 520 Query 947 EIDILRTLY-HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--------------P 991 E++++++L H +++ GCC D+ +++EYV G L+ YL Sbjct 521 ELEVMKSLEPHINVVHLLGCCTDKDPT--FVILEYVNRGKLQTYLRSSRAERHYGNTHGK 578 Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 + + L F Q+ +GM YL ++ IHRDLAARN+L+ +D K+ DFG A+ V Sbjct 579 SNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITS 638 Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111 Y R + +G P+ W A E L + F SD+WSFG+ ++E++T L Sbjct 639 KIYER-KSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVT--------------L 683 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 ++ + + G RL +P+ C E+Y++M CW + RP F +I +L Sbjct 684 GSTPYPGISAADVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDK 743 Query 1172 V 1172 + Sbjct 744 L 744 Score = 220 bits (561), Expect = 1e-58, Method: Composition-based stats. Identities = 61/330 (18%), Positives = 109/330 (33%), Gaps = 50/330 (15%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + + + LG+G V+ V + Sbjct 463 WEFPRYRLKFFNILGEGAFGQVWR-------------------CEATNINGNEGITTVAV 503 Query 642 KVLDPSHHDI-ALAFYETASLMSQVS-HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 K L S ++ +M + H ++ + G C ++ EYV G L +L Sbjct 504 KTLKESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYL 563 Query 700 RRERGH------------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 R R + Q+A + YL ++ ++H ++ RNIL+ Sbjct 564 RSSRAERHYGNTHGKSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILIT---- 619 Query 748 AEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 K++D G ++ + E I W+A E L S D W FG Sbjct 620 ---DDHTCKVADFGFARDVITSKIYERKSEGKLPIRWMATESLYDNI--FSVKSDIWSFG 674 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859 + EI G P S ++ + +RL PE +L + C +++P +RP F Sbjct 675 ILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKPEHCRRELYNIMYYCWSHDPQERPLF 734 Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDP 889 I++ L +L + + Sbjct 735 AEIIQMLDKLLHTEMDYIELERFPDHNYYN 764 >sp|Q2QLG5|MET_CALJA Hepatocyte growth factor receptor OS=Callithrix jacchus OX=9483 GN=MET PE=3 SV=1 Length=1381 Score = 273 bits (697), Expect = 8e-74, Method: Composition-based stats. Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073 ++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1255 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV L+EL+T + +T L +G R Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 232 bits (591), Expect = 9e-61, Method: Composition-based stats. Identities = 64/328 (20%), Positives = 120/328 (37%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D +G Sbjct 1350 VHVNATYVNVKCVAPYPSLLSSQDNTDG 1377 >sp|Q1PDV6|PBL27_ARATH Serine/threonine-protein kinase PBL27 OS=Arabidopsis thaliana OX=3702 GN=PBL27 PE=1 SV=1 Length=513 Score = 258 bits (658), Expect = 8e-74, Method: Composition-based stats. Identities = 82/298 (28%), Positives = 137/298 (46%), Gaps = 19/298 (6%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 + LGEG FG+V Y + TG++VAVK L + G Q + E+ +L L+ Sbjct 82 NFRPECLLGEGGFGRV----YKGRLETTGQIVAVKQLDRN-GLQGNREFLVEVLMLSLLH 136 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEG 1010 H +++ G C D ++ LV EY+PLGSL D+L + + + + A +G Sbjct 137 HPNLVNLIGYCADGDQR--LLVYEYMPLGSLEDHLHDLPPDKEPLDWSTRMTIAAGAAKG 194 Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH + I+RDL + N+LL + K+ DFGLAK P G + + V + Sbjct 195 LEYLHDKANPPVIYRDLKSSNILLGDGYHPKLSDFGLAKLGPVGDKTH-VSTRVMGTYGY 253 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQMTVLR-LT 1125 APE + SDV+SFGV EL+T + + L+ A+ R Sbjct 254 CAPEYAMTGQLTLKSDVYSFGVVFLELITGRKAIDNARAPGEHNLVAWARPLFKDRRKFP 313 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV-HEKYQGQAPS 1182 ++ + + P + + + C + +A+ RP +++ L + + + APS Sbjct 314 KMADPSLQGRYPMRGLYQALAVAAMCLQEQAATRPLIGDVVTALTYLASQTFDPNAPS 371 Score = 240 bits (612), Expect = 2e-67, Method: Composition-based stats. Identities = 73/353 (21%), Positives = 118/353 (33%), Gaps = 63/353 (18%) Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P + L + + K LG+G VY+GRL G Sbjct 49 PEQKKELTAPKEGPTAHIAAQTFTFRELAAATKNFRPECLLGEGGFGRVYKGRLETTGQ- 107 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 V +K LD + F ++S + H +L + Sbjct 108 -----------------------IVAVKQLDRNGLQGNREFLVEVLMLSLLHHPNLVNLI 144 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRR---ERGHVPMAWKMVVAQQLASALSYLENK--- 728 G C G + ++V EY+ G L+ L ++ + + +M +A A L YL +K Sbjct 145 GYCADGDQRLLVYEYMPLGSLEDHLHDLPPDKEPLDWSTRMTIAAGAAKGLEYLHDKANP 204 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERV-----ERIPWLAPE 782 +++ ++ NILL G KLSD G+ LG + + V + APE Sbjct 205 PVIYRDLKSSNILL-------GDGYHPKLSDFGLAKLGPVGDKTHVSTRVMGTYGYCAPE 257 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH----------- 831 G L+ D + FG LE+ +A +R+P E + Sbjct 258 YAMTG--QLTLKSDVYSFGVVFLELITGRKAIDNARAPGEHNLVAWARPLFKDRRKFPKM 315 Query 832 -------RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 R P Q + + CL + RP ++ LT L Sbjct 316 ADPSLQGRYPMRGLYQALAVAAMCLQEQAATRPLIGDVVTALTYLASQTFDPN 368 >sp|Q8AXY6|MUSK_CHICK Muscle, skeletal receptor tyrosine protein kinase OS=Gallus gallus OX=9031 GN=MUSK PE=2 SV=1 Length=947 Score = 268 bits (685), Expect = 9e-74, Method: Composition-based stats. Identities = 88/329 (27%), Positives = 149/329 (45%), Gaps = 41/329 (12%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND-GTGEMVAV 929 N +P + + ++ +RD+GEG FG+V MVAV Sbjct 629 HPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAV 688 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K LK + ++ +++E ++ + +I+K G C K + L+ EY+ G L +Y Sbjct 689 KMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEY 746 Query 990 LPRHS-----------------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 L S + L A+Q+ GMAYL + ++HRDLA Sbjct 747 LRDRSPRNLCSLVQGGLEARACLLNPLALCCTSQLCIAKQVAAGMAYLSERKFVHRDLAT 806 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RN L+ + +VKI DFGL++ + +YY+ E+ P+ W PE + ++ SDVW+ Sbjct 807 RNCLVGENMVVKIADFGLSRNMY-SADYYKANENDAIPIRWMPPESIFYNRYTTESDVWA 865 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 +GV L+E+ ++ M + + G L PD CP E+Y+ Sbjct 866 YGVVLWEIFSYGMQ--------------PYYGMAHEEVIYYVRDGNILSCPDNCPLELYN 911 Query 1147 LMKNCWETEASFRPTFENLIPILKTVHEK 1175 LM+ CW + RP+F ++ IL+ ++E+ Sbjct 912 LMRLCWSKLPADRPSFASIHRILERMYER 940 Score = 244 bits (623), Expect = 9e-66, Method: Composition-based stats. Identities = 70/316 (22%), Positives = 126/316 (40%), Gaps = 58/316 (18%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + I + +G+G V++ R +P V +K+L Sbjct 651 PRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTM-------------------VAVKML 691 Query 645 DPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+ +LR Sbjct 692 KEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEYLRDRS 751 Query 704 GH-----------------VPMAW----KMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 P+A ++ +A+Q+A+ ++YL + VH ++ RN L+ Sbjct 752 PRNLCSLVQGGLEARACLLNPLALCCTSQLCIAKQVAAGMAYLSERKFVHRDLATRNCLV 811 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLSTAMD 796 G + +K++D G+ S + I W+ PE + N +T D Sbjct 812 -------GENMVVKIADFGLSRNMYSADYYKANENDAIPIRWMPPESIF--YNRYTTESD 862 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854 W +G L EI G P + E ++ + + L P+ +L L C + P Sbjct 863 VWAYGVVLWEIFSYGMQPYYGMAHEEVIYYVRDGNILSCPDNCPLELYNLMRLCWSKLPA 922 Query 855 QRPSFRTILRDLTRLQ 870 RPSF +I R L R+ Sbjct 923 DRPSFASIHRILERMY 938 >sp|Q2QL89|MET_MICMU Hepatocyte growth factor receptor OS=Microcebus murinus OX=30608 GN=MET PE=3 SV=1 Length=1382 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073 ++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1256 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV L+EL+T + +T L +G R Sbjct 1257 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1302 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1303 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348 Score = 230 bits (587), Expect = 3e-60, Method: Composition-based stats. Identities = 64/328 (20%), Positives = 119/328 (36%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1119 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D G Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNING 1378 >sp|Q2QLC0|MET_PLEMO Hepatocyte growth factor receptor OS=Plecturocebus moloch OX=9523 GN=MET PE=3 SV=1 Length=1381 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073 ++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1255 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV L+EL+T + +T L +G R Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 231 bits (590), Expect = 1e-60, Method: Composition-based stats. Identities = 64/328 (20%), Positives = 120/328 (37%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D +G Sbjct 1350 VHVNATYVNVKCVAPYPSLLSSQDNADG 1377 >sp|Q07DY1|MET_NOMLE Hepatocyte growth factor receptor OS=Nomascus leucogenys OX=61853 GN=MET PE=3 SV=1 Length=1390 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073 ++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1255 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV L+EL+T + +T L +G R Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 229 bits (584), Expect = 6e-60, Method: Composition-based stats. Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKR 895 + + V Sbjct 1350 VHVNATYVNVKCVAPYP 1366 >sp|P08581|MET_HUMAN Hepatocyte growth factor receptor OS=Homo sapiens OX=9606 GN=MET PE=1 SV=4 Length=1390 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073 ++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1255 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV L+EL+T + +T L +G R Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 229 bits (585), Expect = 6e-60, Method: Composition-based stats. Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKR 895 + + V Sbjct 1350 VHVNATYVNVKCVAPYP 1366 >sp|Q2IBF2|MET_GORGO Hepatocyte growth factor receptor OS=Gorilla gorilla gorilla OX=9595 GN=MET PE=3 SV=1 Length=1390 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073 ++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1255 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV L+EL+T + +T L +G R Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 229 bits (584), Expect = 6e-60, Method: Composition-based stats. Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKR 895 + + V Sbjct 1350 VHVNATYVNVKCVAPYP 1366 >sp|Q2QLF1|MET_PANTR Hepatocyte growth factor receptor OS=Pan troglodytes OX=9598 GN=MET PE=3 SV=1 Length=1390 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073 ++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1255 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV L+EL+T + +T L +G R Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 229 bits (584), Expect = 6e-60, Method: Composition-based stats. Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKR 895 + + V Sbjct 1350 VHVNATYVNVKCVAPYP 1366 >sp|Q2IBD8|MET_PONAB Hepatocyte growth factor receptor OS=Pongo abelii OX=9601 GN=MET PE=3 SV=1 Length=1390 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 93/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073 ++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1255 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV L+EL+T + +T L +G R Sbjct 1256 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1301 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 229 bits (584), Expect = 6e-60, Method: Composition-based stats. Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKR 895 + + V Sbjct 1350 VHVNATYVNVKCVAPYP 1366 >sp|Q07DZ1|MET_COLGU Hepatocyte growth factor receptor OS=Colobus guereza OX=33548 GN=MET PE=3 SV=1 Length=1381 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 90/285 (32%), Positives = 137/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1256 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1303 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 229 bits (584), Expect = 7e-60, Method: Composition-based stats. Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKR 895 + + V Sbjct 1350 VHVNATYVNVKCVAPYP 1366 >sp|P51813|BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX OS=Homo sapiens OX=9606 GN=BMX PE=1 SV=1 Length=675 Score = 262 bits (670), Expect = 1e-73, Method: Composition-based stats. Identities = 84/436 (19%), Positives = 162/436 (37%), Gaps = 64/436 (15%) Query 449 DGIHGPLLEPFVQAKLRPE--DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFP 506 D G + + LR + +G +++ S+ + TV+ S+A + + ++ + Sbjct 295 DWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQVG---MYTVSLFSKAVNDKKGT-VKHYH 350 Query 507 IEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRG 566 + + F S+ +L Q + LR + Sbjct 351 VHTNAENKLYLAENYCFDSIPKLIHYHQHN---SAGMITRLRHP------------VSTK 395 Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 A P +++L + ++EIT L LG G V G+ + Sbjct 396 ANKVPDSVSLGN-GIWELKREEITLLKELGSGQFGVVQLGKWKG---------------- 438 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 + V +K++ F++ A M ++SH L +GVC + +V Sbjct 439 ---------QYDVAVKMIKEGSMS-EDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIV 488 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TEY+ +G L +LR + + + + + +++LE+ +H ++ RN L+ R Sbjct 489 TEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDR-- 546 Query 747 LAEGTSPFIKLSDPGVGLGALSREE--RVER---IPWLAPECLPGGANSLSTAMDKWGFG 801 +K+SD G+ L + V + W APE S+ D W FG Sbjct 547 -----DLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFH--YFKYSSKSDVWAFG 599 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859 + E+ G+ P S+ + HRL P + + + C P +RP+F Sbjct 600 ILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTF 659 Query 860 RTILRDLTRLQPHNLA 875 + +L + L+ + Sbjct 660 QQLLSSIEPLREKDKH 675 Score = 259 bits (661), Expect = 1e-72, Method: Composition-based stats. Identities = 98/351 (28%), Positives = 156/351 (44%), Gaps = 29/351 (8%) Query 829 RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA-- 886 + + + + +L + C P + + H ++ PDS + Sbjct 347 KHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPDSVSLG 406 Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 + + + +++LG G FG V L + D VAVK +K G + Q Sbjct 407 NGIWELKREEITLLKELGSGQFGVVQLGKWKGQYD-----VAVKMIKE--GSMSEDEFFQ 459 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFA 1004 E + L H ++K+ G C E + +V EY+ G L +YL H GL QLL Sbjct 460 EAQTMMKLSHPKLVKFYGVCSK--EYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMC 517 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 +CEGMA+L + +IHRDLAARN L+D D VK+ DFG+ + V + + Y P Sbjct 518 YDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLD--DQYVSSVGTKFP 575 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 V W APE +K+ SDVW+FG+ ++E+ + L ++ Sbjct 576 VKWSAPEVFHYFKYSSKSDVWAFGILMWEVFS--------------LGKQPYDLYDNSQV 621 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 + +G RL RP +Y +M +CW RPTF+ L+ ++ + EK Sbjct 622 VLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQLLSSIEPLREK 672 >sp|Q09YL1|MET_ATEGE Hepatocyte growth factor receptor OS=Ateles geoffroyi OX=9509 GN=MET PE=3 SV=1 Length=1381 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 90/285 (32%), Positives = 137/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1256 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1303 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSAFIGE 1347 Score = 231 bits (589), Expect = 2e-60, Method: Composition-based stats. Identities = 64/328 (20%), Positives = 120/328 (37%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSAFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D +G Sbjct 1350 VHVNATYVNVKCVAPYPSLLSSQDNADG 1377 >sp|Q09YH7|MET_SAIBB Hepatocyte growth factor receptor OS=Saimiri boliviensis boliviensis OX=39432 GN=MET PE=3 SV=1 Length=1381 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 90/285 (32%), Positives = 137/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1256 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1303 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 231 bits (589), Expect = 2e-60, Method: Composition-based stats. Identities = 64/328 (20%), Positives = 120/328 (37%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D +G Sbjct 1350 VHVNATYVNVKCVAPYPSLLSSQDNADG 1377 >sp|F4JZW1|PBL13_ARATH Serine/threonine-protein kinase PBL13 OS=Arabidopsis thaliana OX=3702 GN=PBL13 PE=1 SV=1 Length=494 Score = 257 bits (656), Expect = 1e-73, Method: Composition-based stats. Identities = 82/290 (28%), Positives = 128/290 (44%), Gaps = 14/290 (5%) Query 901 RDLGEGHFGKVSLYCYDPTND--GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 LGEG FG V D + VAVK L D HR + E+ L L H + Sbjct 80 NFLGEGGFGPVHKGFIDDKLRPGLKAQPVAVKLLDLDGLQGHRE-FMTEVMCLGKLKHPN 138 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLH 1015 ++K G C ++ + LV E++P GSL L R + L A + +G+ +LH Sbjct 139 LVKLIGYCCEEAHR--LLVYEFMPRGSLESQLFRRCSLPLPWTTRLNIAYEAAKGLQFLH 196 Query 1016 A--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + I+RD A N+LLD+D K+ DFGLAK P+G + + V + APE + Sbjct 197 EAEKPIIYRDFKASNILLDSDYTAKLSDFGLAKDGPQGDDTH-VSTRVMGTQGYAAPEYI 255 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMT-VLRLTELLERG 1131 SDV+SFGV L ELLT S + ++ L+ A+ + +L +++ Sbjct 256 MTGHLTAKSDVYSFGVVLLELLTGRKSVDIARSSRKETLVEWARPMLNDARKLGRIMDPR 315 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 + + L C RP ++ +L+ + + Y+ P Sbjct 316 LEDQYSETGARKAATLAYQCLRYRPKTRPDISTVVSVLQDIKD-YKDDIP 364 Score = 241 bits (616), Expect = 3e-68, Method: Composition-based stats. Identities = 82/405 (20%), Positives = 149/405 (37%), Gaps = 64/405 (16%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 L++ + RV + + + LG+G V++G + +D L PG Sbjct 59 SDLHVFTQAELRVITQSFSSSNFLGEGGFGPVHKGFI---------------DDKLRPGL 103 Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 + V +K+LD F + ++ H +L + G C ++V E++ Sbjct 104 ---KAQPVAVKLLDLDGLQGHREFMTEVMCLGKLKHPNLVKLIGYCCEEAHRLLVYEFMP 160 Query 692 HGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLA 748 G L+ L R +P ++ +A + A L +L K +++ + NILL Sbjct 161 RGSLESQLFRRCSLPLPWTTRLNIAYEAAKGLQFLHEAEKPIIYRDFKASNILLD----- 215 Query 749 EGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGA 802 + KLSD G+ ++ + + APE + G L+ D + FG Sbjct 216 --SDYTAKLSDFGLAKDGPQGDDTHVSTRVMGTQGYAAPEYIMTG--HLTAKSDVYSFGV 271 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE------PSCPQL------------ATL 844 LLE+ ++ +RS ++ + L + P+L ATL Sbjct 272 VLLELLTGRKSVDIARSSRKETLVEWARPMLNDARKLGRIMDPRLEDQYSETGARKAATL 331 Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 QCL Y P RP T++ L ++ + + + + + P K + D Sbjct 332 AYQCLRYRPKTRPDISTVVSVLQDIKDYKDDIPIGIFTYTVPTKPRREVKETSLQNFDKP 391 Query 905 EGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 SL +D T VK D Q+ ++E+ Sbjct 392 RRETKVTSLQNFDKTRRE------VK----DTSLQNFDKTRREVK 426 >sp|P34152|FAK1_MOUSE Focal adhesion kinase 1 OS=Mus musculus OX=10090 GN=Ptk2 PE=1 SV=4 Length=1052 Score = 269 bits (688), Expect = 1e-73, Method: Composition-based stats. Identities = 100/301 (33%), Positives = 148/301 (49%), Gaps = 24/301 (8%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQH 940 P++ + ++ R +GEG FG V Y P N VA+K K Sbjct 407 YTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGVYLSPENPALA--VAIKTCKNCTSDSV 464 Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLA 998 R + QE +R H HI+K G E + ++ME LG LR +L ++S+ LA Sbjct 465 REKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLA 521 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 L+L+A Q+ +AYL ++ ++HRD+AARNVL+ ++ VK+GDFGL++ + + Y Sbjct 522 SLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKA 579 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 G P+ W APE + +F ASDVW FGV ++E+L H Sbjct 580 SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ--------------G 625 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 + + +E GERLP P CP +Y LM CW + S RP F L L T+ E+ + Sbjct 626 VKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKV 685 Query 1179 Q 1179 Q Sbjct 686 Q 686 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 70/305 (23%), Positives = 124/305 (41%), Gaps = 39/305 (13%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 T + + + ++ I +G+G +V++G V Sbjct 406 TYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQG---------------------VYLSP 444 Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 L V +K D F + A M Q H H+ + GV P ++ E Sbjct 445 ENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCT 503 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G L +L+ + + +A ++ A QL++AL+YLE+K VH ++ RN+L++ + Sbjct 504 LGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS-------S 556 Query 752 SPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 + +KL D G+ I W+APE + ++A D W FG + E Sbjct 557 NDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWE 614 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 I G P Q ++ + R +P P L +L ++C Y+P++RP F + Sbjct 615 ILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKA 674 Query 865 DLTRL 869 L+ + Sbjct 675 QLSTI 679 Score = 38.5 bits (88), Expect = 0.45, Method: Composition-based stats. Identities = 34/193 (18%), Positives = 70/193 (36%), Gaps = 29/193 (15%) Query 120 PAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHF 179 P ++ Q + D + + ++Q K +++ ++A ++ Sbjct 117 PEEWKYELRIRYLPKGFLNQFTE--DKPTLNFFYQQVKSDYMQEIA-----DQVDQEIAL 169 Query 180 KNESLGM--AFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNV 237 K L + ++ + AL E + K K P+S ++ + R ++ Sbjct 170 KLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTL--RKLIQQT 227 Query 238 FRRFLRDFQPGRLSQQMVMVKYLATLERLAP--RFGTERVP-------VCHLRLLAQAEG 288 FR+F L+++ ++K+ E L+P RF E + + L E Sbjct 228 FRQF------ANLNREESILKF---FEILSPVYRFDKECFKCALGSSWIISVELAIGPEE 278 Query 289 EPCYIRDSGVAPT 301 Y+ D G PT Sbjct 279 GISYLTDKGCNPT 291 >sp|Q07DV8|MET_AOTNA Hepatocyte growth factor receptor OS=Aotus nancymaae OX=37293 GN=MET PE=3 SV=1 Length=1381 Score = 272 bits (695), Expect = 1e-73, Method: Composition-based stats. Identities = 90/285 (32%), Positives = 137/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1256 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1303 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 232 bits (591), Expect = 1e-60, Method: Composition-based stats. Identities = 64/328 (20%), Positives = 120/328 (37%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D +G Sbjct 1350 VHVNATYVNVKCVAPYPSLLSSQDNPDG 1377 >sp|Q2IBG7|MET_EULMM Hepatocyte growth factor receptor OS=Eulemur macaco macaco OX=30603 GN=MET PE=3 SV=1 Length=1382 Score = 272 bits (695), Expect = 1e-73, Method: Composition-based stats. Identities = 90/285 (32%), Positives = 137/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348 Score = 230 bits (587), Expect = 3e-60, Method: Composition-based stats. Identities = 64/328 (20%), Positives = 119/328 (36%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1119 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D G Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNVNG 1378 >sp|Q54TA1|DRKC_DICDI Probable serine/threonine-protein kinase drkC OS=Dictyostelium discoideum OX=44689 GN=drkC PE=3 SV=1 Length=749 Score = 264 bits (674), Expect = 1e-73, Method: Composition-based stats. Identities = 76/279 (27%), Positives = 122/279 (44%), Gaps = 29/279 (10%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA--LKADCGPQHRSGWKQEIDILRTLYHE 957 +G G +V + G +VA+K L + + QE I+ L H Sbjct 494 QNRIGRGSCAEVFTGTWR------GIIVAIKKAKLLNEDDEDFLNELAQEATIMSQLRHP 547 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLH 1015 +I ++ G C + E + +VMEY+PLGSL L S + ++ A I +GM YLH Sbjct 548 NICQFLGTCNNPPE--ILIVMEYMPLGSLYRILHDPSISLDWPRMKSMALDIAKGMNYLH 605 Query 1016 --AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRDL + N+L+D VKI DFGL+ + + +P W APE L Sbjct 606 CCDPIVIHRDLKSHNLLVDEHYRVKISDFGLSTRFKKHLDKKTAMTPVGTPC-WTAPEVL 664 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + + +DV+SF + L+E++T D QG T + + + R Sbjct 665 RNDPYTEKADVFSFAIVLWEIVTREDPY--------------QGMPTFQIVISVGQHKLR 710 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P + L+ CW + RP+F+ ++ L+ + Sbjct 711 PIVPPQVSAPFTRLITECWSEDPQQRPSFQEIVKRLEAM 749 Score = 233 bits (594), Expect = 4e-63, Method: Composition-based stats. Identities = 75/418 (18%), Positives = 143/418 (34%), Gaps = 57/418 (14%) Query 472 LIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGA 531 ++ +++ P +T+ F I ++ ++ + + Sbjct 369 MLQSNSTTPSDYNVTIQLSEDGGSSF--CLNTTFFIYTAASIPFVKPTSPNYQKIIYIVV 426 Query 532 ALQGCLLR--AGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQ-----LSFHRV 584 + +L A F +R + S + G R+ L + Sbjct 427 GVGIAVLLIIAVGIYFIIRLRIKNKRLNGSKHALPIGINDDERSPLLKTDYKTLFEIKPI 486 Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV- 643 D EI + +G+G+ V+ G R + V +K Sbjct 487 DISEIVVQNRIGRGSCAEVFTGTWRG--------------------------IIVAIKKA 520 Query 644 --LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 L+ D + A++MSQ+ H ++ G C PE ++V EY+ G L L Sbjct 521 KLLNEDDEDFLNELAQEATIMSQLRHPNICQFLGTCNNPPEILIVMEYMPLGSLYRILHD 580 Query 702 ERGHVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + +A +A ++YL + ++H ++ N+L+ +K+SD Sbjct 581 PSISLDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDE-------HYRVKISD 633 Query 760 PGVG------LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ L + V W APE L + + D + F L EI + Sbjct 634 FGLSTRFKKHLDKKTAMTPVGTPCWTAPEVLRN--DPYTEKADVFSFAIVLWEIVTREDP 691 Query 814 PLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + Q + R +P L ++C + +P QRPSF+ I++ L + Sbjct 692 YQGMPTFQIVISVGQHKLRPIVPPQVSAPFTRLITECWSEDPQQRPSFQEIVKRLEAM 749 >sp|A0M8R7|MET_PAPAN Hepatocyte growth factor receptor OS=Papio anubis OX=9555 GN=MET PE=3 SV=1 Length=1381 Score = 272 bits (695), Expect = 1e-73, Method: Composition-based stats. Identities = 90/285 (32%), Positives = 137/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1256 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1303 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 229 bits (583), Expect = 8e-60, Method: Composition-based stats. Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKR 895 + + V Sbjct 1350 VHVNATYVNVKCVAPYP 1366 >sp|Q1PE89|PBL24_ARATH Probable serine/threonine-protein kinase PBL24 OS=Arabidopsis thaliana OX=3702 GN=PBL24 PE=2 SV=1 Length=389 Score = 253 bits (646), Expect = 1e-73, Method: Composition-based stats. Identities = 89/340 (26%), Positives = 137/340 (40%), Gaps = 18/340 (5%) Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910 YE P N + S ++ +GEG FG+ Sbjct 25 YEQQNLPRNDRRQITTWEAVGTNKESPKNIKAKSFKFRELATATNSFRQEFLIGEGGFGR 84 Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970 V Y + TG++VAVK L + G Q + EI L L+H ++ G C D Sbjct 85 V----YKGKMEKTGQVVAVKQLDRN-GLQGNREFLVEIFRLSLLHHPNLANLIGYCLDGD 139 Query 971 EKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHR 1022 ++ LV E++PLGSL D+L + + + A +G+ YLH + I+R Sbjct 140 QR--LLVHEFMPLGSLEDHLLDVVVGQQPLDWNSRIRIALGAAKGLEYLHEKANPPVIYR 197 Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082 D + N+LL+ D K+ DFGLAK G + V + APE K + S Sbjct 198 DFKSSNILLNVDFDAKLSDFGLAKLGSVG-DTQNVSSRVVGTYGYCAPEYHKTGQLTVKS 256 Query 1083 DVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQG-QMTVLRLTELLERGERLPRPDKC 1140 DV+SFGV L EL+T + P L+ AQ R EL + + P+K Sbjct 257 DVYSFGVVLLELITGKRVIDTTRPCHEQNLVTWAQPIFREPNRFPELADPLLQGEFPEKS 316 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180 + + C + E RP +++ L + + + Sbjct 317 LNQAVAIAAMCLQEEPIVRPLISDVVTALSFMSTETGSPS 356 Score = 230 bits (587), Expect = 1e-65, Method: Composition-based stats. Identities = 72/346 (21%), Positives = 122/346 (35%), Gaps = 65/346 (19%) Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEGS 613 + + + + SP+ + F + Q +G+G VY+G++ G Sbjct 36 RQITTWEAVGTNKESPKNIKAKSFKFRELATATNSFRQEFLIGEGGFGRVYKGKMEKTGQ 95 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 V +K LD + F +S + H +LA + Sbjct 96 ------------------------VVAVKQLDRNGLQGNREFLVEIFRLSLLHHPNLANL 131 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYLENK-- 728 G C+ G + ++V E++ G L+ L G P+ W ++ +A A L YL K Sbjct 132 IGYCLDGDQRLLVHEFMPLGSLEDHLLDVVVGQQPLDWNSRIRIALGAAKGLEYLHEKAN 191 Query 729 -NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAP 781 +++ + NILL KLSD G+ + + V + AP Sbjct 192 PPVIYRDFKSSNILLN-------VDFDAKLSDFGLAKLGSVGDTQNVSSRVVGTYGYCAP 244 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ------HRLPE 835 E G L+ D + FG LLE+ +R E+ Q +R PE Sbjct 245 EYHKTG--QLTVKSDVYSFGVVLLELITGKRVIDTTRPCHEQNLVTWAQPIFREPNRFPE 302 Query 836 PSCPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + P L + + CL EP RP ++ L+ + Sbjct 303 LADPLLQGEFPEKSLNQAVAIAAMCLQEEPIVRPLISDVVTALSFM 348 >sp|Q07E48|MET_DASNO Hepatocyte growth factor receptor OS=Dasypus novemcinctus OX=9361 GN=MET PE=3 SV=1 Length=1381 Score = 272 bits (695), Expect = 1e-73, Method: Composition-based stats. Identities = 91/286 (32%), Positives = 140/286 (49%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V ++D AVK+L S + E I++ H Sbjct 1080 HFNEVIGRGHFGCVYHGTLLDSDDK-KIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073 ++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1256 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV L+EL+T + +T L +G R Sbjct 1257 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1302 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1303 LLQPEYCPDRLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348 Score = 228 bits (581), Expect = 1e-59, Method: Composition-based stats. Identities = 64/333 (19%), Positives = 121/333 (36%), Gaps = 46/333 (14%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L +++ +K L+ Sbjct 1081 FNEVIGRGHFGCVYHGTLLDSD---------------------DKKIHCAVKSLNRITDI 1119 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE +L + +C + RPSF ++ ++ + + + Sbjct 1291 FDITVYLLQGRRLLQPEYCPDRLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911 + + + L DL G+V Sbjct 1351 VHVNATYVNVKCIAPYPSLLSQDDLD----GEV 1379 >sp|O35346|FAK1_RAT Focal adhesion kinase 1 OS=Rattus norvegicus OX=10116 GN=Ptk2 PE=1 SV=1 Length=1055 Score = 269 bits (688), Expect = 1e-73, Method: Composition-based stats. Identities = 100/301 (33%), Positives = 148/301 (49%), Gaps = 24/301 (8%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQH 940 P++ + ++ R +GEG FG V Y P N VA+K K Sbjct 407 YTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGVYLSPENPALA--VAIKTCKNCTSDSV 464 Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLA 998 R + QE +R H HI+K G E + ++ME LG LR +L ++S+ LA Sbjct 465 REKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKYSLDLA 521 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 L+L+A Q+ +AYL ++ ++HRD+AARNVL+ ++ VK+GDFGL++ + + Y Sbjct 522 SLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--TYYKA 579 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 G P+ W APE + +F ASDVW FGV ++E+L H Sbjct 580 SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ--------------G 625 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 + + +E GERLP P CP +Y LM CW + S RP F L L T+ E+ + Sbjct 626 VKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKV 685 Query 1179 Q 1179 Q Sbjct 686 Q 686 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 70/305 (23%), Positives = 124/305 (41%), Gaps = 39/305 (13%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 T + + + ++ I +G+G +V++G V Sbjct 406 TYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQG---------------------VYLSP 444 Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 L V +K D F + A M Q H H+ + GV P ++ E Sbjct 445 ENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCT 503 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G L +L+ + + +A ++ A QL++AL+YLE+K VH ++ RN+L++ + Sbjct 504 LGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS-------S 556 Query 752 SPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 + +KL D G+ I W+APE + ++A D W FG + E Sbjct 557 NDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWE 614 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 I G P Q ++ + R +P P L +L ++C Y+P++RP F + Sbjct 615 ILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKA 674 Query 865 DLTRL 869 L+ + Sbjct 675 QLSTI 679 Score = 37.4 bits (85), Expect = 1.1, Method: Composition-based stats. Identities = 34/193 (18%), Positives = 70/193 (36%), Gaps = 29/193 (15%) Query 120 PAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHF 179 P ++ Q + D + + ++Q K +++ ++A ++ Sbjct 117 PEEWKYELRIRYLPKGFLNQFTE--DKPTLNFFYQQVKSDYMLEIA-----DQVDQDIAL 169 Query 180 KNESLGM--AFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRLRLRNV 237 K L + ++ + AL E + K K P+S ++ + R ++ Sbjct 170 KLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTL--RKLIQQT 227 Query 238 FRRFLRDFQPGRLSQQMVMVKYLATLERLAP--RFGTERVP-------VCHLRLLAQAEG 288 FR+F L+++ ++K+ E L+P RF E + + L E Sbjct 228 FRQF------ANLNREESILKF---FEILSPVYRFDKECFKCALGSSWIISVELAIGPEE 278 Query 289 EPCYIRDSGVAPT 301 Y+ D G PT Sbjct 279 GISYLTDKGCNPT 291 >sp|Q2IBA6|MET_CHLAE Hepatocyte growth factor receptor OS=Chlorocebus aethiops OX=9534 GN=MET PE=1 SV=1 Length=1381 Score = 272 bits (695), Expect = 1e-73, Method: Composition-based stats. Identities = 90/285 (32%), Positives = 137/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V NDG AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1256 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1303 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1347 Score = 229 bits (583), Expect = 8e-60, Method: Composition-based stats. Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G+++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------GKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKR 895 + + V Sbjct 1350 VHVNATYVNVKCVAPYP 1366 >sp|O49840|PBL3_ARATH Probable serine/threonine-protein kinase PBL3 OS=Arabidopsis thaliana OX=3702 GN=PBL3 PE=1 SV=1 Length=426 Score = 254 bits (649), Expect = 1e-73, Method: Composition-based stats. Identities = 89/288 (31%), Positives = 130/288 (45%), Gaps = 16/288 (6%) Query 903 LGEGHFGKVSLYCYDPT-----NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LGEG FG V D T G+G +VAVK LK + G Q W E++ L L H Sbjct 89 LGEGGFGYVFKGWIDGTTLTASKPGSGIVVAVKKLKTE-GYQGHKEWLTEVNYLGQLSHP 147 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYL 1014 +++K G C + GE L LV E++P GSL ++L R + A + A +G+ +L Sbjct 148 NLVKLVGYCVE-GENRL-LVYEFMPKGSLENHLFRRGAQPLTWAIRMKVAIGAAKGLTFL 205 Query 1015 H--AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 H I+RD A N+LLD + K+ DFGLAKA P G + + V + APE Sbjct 206 HDAKSQVIYRDFKAANILLDAEFNSKLSDFGLAKAGPTGDKTH-VSTQVMGTHGYAAPEY 264 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE-LIGIAQGQM-TVLRLTELLER 1130 + + SDV+SFGV L ELL+ + + L+ A + +L +++ Sbjct 265 VATGRLTAKSDVYSFGVVLLELLSGRRAVDKSKVGMEQSLVDWATPYLGDKRKLFRIMDT 324 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P K L C +A RP ++ L + G Sbjct 325 RLGGQYPQKGAYTAASLALQCLNPDAKLRPKMSEVLAKLDQLESTKPG 372 Score = 235 bits (599), Expect = 1e-66, Method: Composition-based stats. Identities = 73/341 (21%), Positives = 128/341 (38%), Gaps = 55/341 (16%) Query 560 NLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 +L R + NL +F+ + + S LG+G V++G + Sbjct 52 SLPTPRTEGEILSSPNLKAFTFNELKNATRNFRPDSLLGEGGFGYVFKGWI--------- 102 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 + + G + V +K L + + + + Q+SH +L + G C Sbjct 103 ------DGTTLTASKPGSGIVVAVKKLKTEGYQGHKEWLTEVNYLGQLSHPNLVKLVGYC 156 Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN--KNLVHG 733 V G ++V E++ G L+ L R RG P+ W +M VA A L++L + +++ Sbjct 157 VEGENRLLVYEFMPKGSLENHLFR-RGAQPLTWAIRMKVAIGAAKGLTFLHDAKSQVIYR 215 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGG 787 + NILL KLSD G+ + ++ + + APE + G Sbjct 216 DFKAANILLD-------AEFNSKLSDFGLAKAGPTGDKTHVSTQVMGTHGYAAPEYVATG 268 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR------------------ 829 L+ D + FG LLE+ A +S+ E+ Sbjct 269 --RLTAKSDVYSFGVVLLELLSGRRAVDKSKVGMEQSLVDWATPYLGDKRKLFRIMDTRL 326 Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + P+ A+L QCL + RP +L L +L+ Sbjct 327 GGQYPQKGAYTAASLALQCLNPDAKLRPKMSEVLAKLDQLE 367 >sp|Q09YK0|MET_MUNMU Hepatocyte growth factor receptor OS=Muntiacus muntjak OX=9888 GN=MET PE=3 SV=1 Length=1382 Score = 272 bits (695), Expect = 2e-73, Method: Composition-based stats. Identities = 90/285 (32%), Positives = 136/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V ND AVK+L S + E I++ H Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLA 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ V + Y + PV W A E L+ Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQ 1257 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 LQPEYCPDALYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348 Score = 229 bits (583), Expect = 8e-60, Method: Composition-based stats. Identities = 63/328 (19%), Positives = 118/328 (36%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L +++ +K L+ Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1119 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMEYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDVYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1291 FDITVYLLQGRRLLQPEYCPDALYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D G Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNVNG 1378 >sp|Q60750|EPHA1_MOUSE Ephrin type-A receptor 1 OS=Mus musculus OX=10090 GN=Epha1 PE=1 SV=2 Length=977 Score = 268 bits (684), Expect = 2e-73, Method: Composition-based stats. Identities = 87/307 (28%), Positives = 140/307 (46%), Gaps = 20/307 (7%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 L+P+ +L +GEG FG+V + + V Sbjct 596 WLKPYVDLQAYEDPAQGALDFAQELDPAWLIVDTVIGEGEFGEVYRGALRLPSQDC-KTV 654 Query 928 AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 A+K LK + + +E I+ H HI++ +G + K + ++ E++ G+L Sbjct 655 AIKTLKDTSPDGYWWNFLREATIMGQFNHPHILRLEGVITKR--KPIMIITEFMENGALD 712 Query 988 DYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L + QL+ I GM L +Y+HRDLAARN+L++ + K+ DFGL Sbjct 713 AFLKEREDQLAPGQLVAMLLGIASGMNCLSGHNYVHRDLAARNILVNQNLCCKVSDFGLT 772 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 + + + Y + G P+ W APE + F ASDVWSFG+ ++E+L+ D Sbjct 773 RLLDDFDGTYET-QGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDK----- 826 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 G+M+ + + +E G RLP P CP +Y LMKNCW + + RP F L Sbjct 827 ---------PYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFLQL 877 Query 1166 IPILKTV 1172 L+ + Sbjct 878 QAHLEQL 884 Score = 249 bits (637), Expect = 3e-67, Method: Composition-based stats. Identities = 73/302 (24%), Positives = 120/302 (40%), Gaps = 39/302 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D + + +G+G VY G LR+ V + Sbjct 618 QELDPAWLIVDTVIGEGEFGEVYRGALRLPSQDCK---------------------TVAI 656 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + D F A++M Q +H H+ + GV + +++TE++E+G LD +L+ Sbjct 657 KTLKDTSPDGYWWNFLREATIMGQFNHPHILRLEGVITKRKPIMIITEFMENGALDAFLK 716 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + + + +AS ++ L N VH ++ RNIL+ + + K+SD Sbjct 717 EREDQLAPGQLVAMLLGIASGMNCLSGHNYVHRDLAARNILVNQ-------NLCCKVSDF 769 Query 761 GVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ G + I W APE + +TA D W FG + E+ G+ P Sbjct 770 GLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRI--FTTASDVWSFGIVMWEVLSFGDKP 827 Query 815 LQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 S E + +RLP P CP L L C Y+ +RP F + L +L Sbjct 828 YGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFLQLQAHLEQLLTD 887 Query 873 NL 874 Sbjct 888 PH 889 >sp|Q00PJ8|MET_ATEAB Hepatocyte growth factor receptor OS=Atelerix albiventris OX=9368 GN=MET PE=3 SV=1 Length=1382 Score = 271 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 89/285 (31%), Positives = 137/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V ND AVK+L S + E I++ H Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD + VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1198 SKKFVHRDLAARNCMLDENFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348 Score = 228 bits (580), Expect = 2e-59, Method: Composition-based stats. Identities = 60/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L +++ +K L+ Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1119 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L + +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDE-------NFTVKVADFGLARDMYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKR 895 + + V Sbjct 1351 VHVNATYVNIKCVAPYP 1367 >sp|Q09147|FGFR2_DROME Fibroblast growth factor receptor homolog 2 OS=Drosophila melanogaster OX=7227 GN=btl PE=2 SV=3 Length=1052 Score = 269 bits (687), Expect = 2e-73, Method: Composition-based stats. Identities = 99/334 (30%), Positives = 159/334 (48%), Gaps = 44/334 (13%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---EMVAVKALKAD 935 + P ++ L LGEG FG+V + + +VAVK +K + Sbjct 694 FNEYEFPLDSNWEIPRQQLSLGSILGEGAFGRVVMAEAEGLPRSPQLAETIVAVKMVKEE 753 Query 936 CGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994 + +E+++++ + H +II GCC G L +++EY P G+L+D+L ++ Sbjct 754 HTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGG--PLWVIVEYAPHGNLKDFLKQNR 811 Query 995 ------------------------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030 +G +L FA QI GM YL ++ IHRDLAARNVL Sbjct 812 PGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVL 871 Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 + + ++KI DFGLA+ + + EYYR +G P+ W APE L+E K+ SDVWS+GV Sbjct 872 VSDGYVMKIADFGLARDIQD-TEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVL 930 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 L+E++T+ D ++ L L G+R+ +P KC +Y +M+ Sbjct 931 LWEIMTYGDQPY-------------PHILSAEELYSYLITGQRMEKPAKCSLNIYVVMRQ 977 Query 1151 CWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 CW E+ RPTF L+ + ++ + Sbjct 978 CWHFESCARPTFAELVESFDGILQQASSNPNDAY 1011 Score = 236 bits (603), Expect = 8e-63, Method: Composition-based stats. Identities = 64/349 (18%), Positives = 124/349 (36%), Gaps = 59/349 (17%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 S + +++++ S LG+G V + E +P Sbjct 696 EYEFPLDSNWEIPRQQLSLGSILGEGAFGRV-----------------VMAEAEGLPRSP 738 Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690 + E V +K++ H D +A +M + H ++ + G C +G ++ EY Sbjct 739 QLAETIVAVKMVKEEHTDTDMASLVREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYA 798 Query 691 EHGPLDVWLRRERG----------------------HVPMAWKMVVAQQLASALSYLENK 728 HG L +L++ R H+ A Q+A + YL ++ Sbjct 799 PHGNLKDFLKQNRPGAPQRRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASR 858 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSREERVERIP--WLAPE 782 +H ++ RN+L++ +K++D G+ R+ R+P W+APE Sbjct 859 RCIHRDLAARNVLVS-------DGYVMKIADFGLARDIQDTEYYRKNTNGRLPIKWMAPE 911 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCP 839 L + D W +G L EI G+ P +E+ + ++ P Sbjct 912 SLQE--KKYDSQSDVWSYGVLLWEIMTYGDQPYPHILSAEELYSYLITGQRMEKPAKCSL 969 Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASD 888 + + QC +E RP+F ++ + ++ D Sbjct 970 NIYVVMRQCWHFESCARPTFAELVESFDGILQQASSNPNDAYLDLSMPM 1018 >sp|Q62838|MUSK_RAT Muscle, skeletal receptor tyrosine protein kinase OS=Rattus norvegicus OX=10116 GN=Musk PE=1 SV=1 Length=868 Score = 265 bits (678), Expect = 2e-73, Method: Composition-based stats. Identities = 86/336 (26%), Positives = 150/336 (45%), Gaps = 43/336 (13%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND-GTGEMVAV 929 N +P + + ++ +RD+GEG FG+V MVAV Sbjct 548 HPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAV 607 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K LK + ++ +++E ++ + +I+K G C K + L+ EY+ G L ++ Sbjct 608 KMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEF 665 Query 990 LPR-------------------------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDL 1024 L + A+ L A+Q+ GMAYL + ++HRDL Sbjct 666 LRSMSPHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDL 725 Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084 A RN L+ + +VKI DFGL++ + +YY+ + P+ W PE + ++ SDV Sbjct 726 ATRNCLVGENMVVKIADFGLSRNIY-SADYYKADGNDAIPIRWMPPESIFYNRYTTESDV 784 Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144 W++GV L+E+ ++ M + + G L P+ CP E+ Sbjct 785 WAYGVVLWEIFSYGLQ--------------PYYGMAHEEVIYYVRDGNILACPENCPLEL 830 Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180 Y+LM+ CW + RP+F ++ IL+ + E+ +G Sbjct 831 YNLMRLCWSKLPADRPSFCSIHRILQRMCERAEGTV 866 Score = 245 bits (625), Expect = 2e-66, Method: Composition-based stats. Identities = 71/317 (22%), Positives = 127/317 (40%), Gaps = 60/317 (19%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + I + +G+G V++ R +P V +K+L Sbjct 570 PRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTM-------------------VAVKML 610 Query 645 DPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--- 700 D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+ +LR Sbjct 611 KEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMS 670 Query 701 ------------------RERGHVPMA--WKMVVAQQLASALSYLENKNLVHGNVCGRNI 740 G P++ ++ +A+Q+A+ ++YL + VH ++ RN Sbjct 671 PHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNC 730 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLSTA 794 L+ G + +K++D G+ S + I W+ PE + N +T Sbjct 731 LV-------GENMVVKIADFGLSRNIYSADYYKADGNDAIPIRWMPPESIF--YNRYTTE 781 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYE 852 D W +G L EI G P + E ++ + + L PE +L L C + Sbjct 782 SDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILACPENCPLELYNLMRLCWSKL 841 Query 853 PTQRPSFRTILRDLTRL 869 P RPSF +I R L R+ Sbjct 842 PADRPSFCSIHRILQRM 858 >sp|Q8GYA4|CRK10_ARATH Cysteine-rich receptor-like protein kinase 10 OS=Arabidopsis thaliana OX=3702 GN=CRK10 PE=1 SV=3 Length=669 Score = 261 bits (666), Expect = 2e-73, Method: Composition-based stats. Identities = 74/294 (25%), Positives = 119/294 (40%), Gaps = 17/294 (6%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 + +G+G FG+V G VAVK L G +K Sbjct 337 DYRTIQTATDDFVESNKIGQGGFGEVYKGTL-----SDGTEVAVKRLSKSSGQGEVE-FK 390 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLL 1001 E+ ++ L H ++++ G C D E+ LV EYVP SL +L + + + Sbjct 391 NEVVLVAKLQHRNLVRLLGFCLDGEER--VLVYEYVPNKSLDYFLFDPAKKGQLDWTRRY 448 Query 1002 LFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 + G+ YLH IHRDL A N+LLD D KI DFG+A+ Sbjct 449 KIIGGVARGILYLHQDSRLTIIHRDLKASNILLDADMNPKIADFGMARIFGLDQTEENTS 508 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQG 1117 + +PE ++ SDV+SFGV + E+++ +SS +L+ A G Sbjct 509 R-IVGTYGYMSPEYAMHGQYSMKSDVYSFGVLVLEIISGKKNSSFYQTDGAHDLVSYAWG 567 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + R EL++ H+ C + + + RPT ++ +L + Sbjct 568 LWSNGRPLELVDPAIVENCQRNEVVRCVHIGLLCVQEDPAERPTLSTIVLMLTS 621 Score = 238 bits (607), Expect = 2e-65, Method: Composition-based stats. Identities = 66/351 (19%), Positives = 121/351 (34%), Gaps = 64/351 (18%) Query 545 FSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTRTN 602 F C L + S A T + QL + + + + + +GQG Sbjct 302 FIAGYCFLTRRARKSYYTPSAFAGDDITTADSLQLDYRTIQTATDDFVESNKIGQGGFGE 361 Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662 VY+G L V +K L S + F L+ Sbjct 362 VYKGTLSDG-------------------------TEVAVKRLSKSSGQGEVEFKNEVVLV 396 Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR--ERGHVPMAWKMVVAQQLAS 720 +++ H +L + G C+ G E ++V EYV + LD +L ++G + + + +A Sbjct 397 AKLQHRNLVRLLGFCLDGEERVLVYEYVPNKSLDYFLFDPAKKGQLDWTRRYKIIGGVAR 456 Query 721 ALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREE 771 + YL + ++H ++ NILL K++D G+ + Sbjct 457 GILYLHQDSRLTIIHRDLKASNILLD-------ADMNPKIADFGMARIFGLDQTEENTSR 509 Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS---PSEKEHFY- 827 V +++PE G S D + FG +LEI + ++ + + Sbjct 510 IVGTYGYMSPEYAMHG--QYSMKSDVYSFGVLVLEIISGKKNSSFYQTDGAHDLVSYAWG 567 Query 828 -QRQHRLPEPSCPQLAT------------LTSQCLTYEPTQRPSFRTILRD 865 R E P + + C+ +P +RP+ TI+ Sbjct 568 LWSNGRPLELVDPAIVENCQRNEVVRCVHIGLLCVQEDPAERPTLSTIVLM 618 >sp|Q9M0X5|CRK25_ARATH Cysteine-rich receptor-like protein kinase 25 OS=Arabidopsis thaliana OX=3702 GN=CRK25 PE=3 SV=1 Length=675 Score = 261 bits (666), Expect = 3e-73, Method: Composition-based stats. Identities = 80/280 (29%), Positives = 121/280 (43%), Gaps = 17/280 (6%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG G FG+V TGE VA+K L Q +K E+D++ L H ++ Sbjct 351 NKLGHGGFGEVYKGQL-----ITGETVAIKRLSQGST-QGAEEFKNEVDVVAKLQHRNLA 404 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016 K G C D EK LV E+VP SL +L R + + + I G+ YLH Sbjct 405 KLLGYCLDGEEK--ILVYEFVPNKSLDYFLFDNEKRRVLDWQRRYKIIEGIARGILYLHR 462 Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRDL A N+LLD D KI DFG+A+ + + +PE Sbjct 463 DSRLTIIHRDLKASNILLDADMHPKISDFGMARIFGVDQTQANTKR-IVGTYGYMSPEYA 521 Query 1074 KEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 K+ SDV+SFGV + EL+T +SS +L+ EL++ Sbjct 522 IHGKYSVKSDVYSFGVLVLELITGKKNSSFYEEDGLGDLVTYVWKLWVENSPLELVDEAM 581 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 R H+ C + ++S RP+ ++++ ++ + Sbjct 582 RGNFQTNEVIRCIHIALLCVQEDSSERPSMDDILVMMNSF 621 Score = 251 bits (640), Expect = 9e-70, Method: Composition-based stats. Identities = 76/382 (20%), Positives = 135/382 (35%), Gaps = 69/382 (18%) Query 517 EGWGRSFPSV-RELGAALQGCLLRAGDDCFSL-RRCCLPQPGETSNLIIMRGARASPRTL 574 +G G++ + + + C+L G C+ L RR ET +L S TL Sbjct 276 KGKGKNLTVIVTAIAVPVSVCVLLLGAMCWLLARRRNNKLSAETEDL--DEDGITSTETL 333 Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 Q S + ++ + LG G VY+G+L + Sbjct 334 QF-QFSAIEAATNKFSESNKLGHGGFGEVYKGQLITGET--------------------- 371 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 V +K L A F +++++ H +LA + G C+ G E I+V E+V + Sbjct 372 ----VAIKRLSQGSTQGAEEFKNEVDVVAKLQHRNLAKLLGYCLDGEEKILVYEFVPNKS 427 Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAE 749 LD +L + W + + + +A + YL + ++H ++ NILL Sbjct 428 LDYFLFDNEKRRVLDWQRRYKIIEGIARGILYLHRDSRLTIIHRDLKASNILLD------ 481 Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 K+SD G+ + + V +++PE G S D + FG Sbjct 482 -ADMHPKISDFGMARIFGVDQTQANTKRIVGTYGYMSPEYAIHG--KYSVKSDVYSFGVL 538 Query 804 LLEICFDGEAP------------------LQSRSPSEKEHFYQRQHRLPEPSCPQLATLT 845 +LE+ + SP E R + + + Sbjct 539 VLELITGKKNSSFYEEDGLGDLVTYVWKLWVENSPLELVDEAMRGNFQTNEVIRCIH-IA 597 Query 846 SQCLTYEPTQRPSFRTILRDLT 867 C+ + ++RPS IL + Sbjct 598 LLCVQEDSSERPSMDDILVMMN 619 >sp|Q07E24|MET_MUSPF Hepatocyte growth factor receptor OS=Mustela putorius furo OX=9669 GN=MET PE=3 SV=1 Length=1382 Score = 271 bits (693), Expect = 3e-73, Method: Composition-based stats. Identities = 89/285 (31%), Positives = 136/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V ND AVK+L S + E I++ H Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348 Score = 229 bits (583), Expect = 1e-59, Method: Composition-based stats. Identities = 63/328 (19%), Positives = 120/328 (37%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L +++ +K L+ Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1119 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D+ +G Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDIIDG 1378 >sp|Q9ZQ31|STY13_ARATH Serine/threonine-protein kinase STY13 OS=Arabidopsis thaliana OX=3702 GN=STY13 PE=1 SV=2 Length=411 Score = 253 bits (645), Expect = 3e-73, Method: Composition-based stats. Identities = 80/314 (25%), Positives = 129/314 (41%), Gaps = 34/314 (11%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-- 932 D D R L +G FGK+ Y GE VA+K L Sbjct 108 MDTRYPTEGLTNYDEWTIDLRKLNMGPAFAQGAFGKLYKGTY------NGEDVAIKILER 161 Query 933 ---KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 + ++QE+ +L L H +I+++ G C +V EY GS+R + Sbjct 162 PENSPEKAQFMEQQFQQEVSMLANLKHPNIVRFIGACRKPM--VWCIVTEYAKGGSVRQF 219 Query 990 LPRH---SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 L R ++ L + A + GMAY+H +++IHRDL + N+L+ D+ +KI DFG+A+ Sbjct 220 LTRRQNRAVPLKLAVKQALDVARGMAYVHGRNFIHRDLKSDNLLISADKSIKIADFGVAR 279 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 + W APE ++ + DV+SFG+ L+EL+T Sbjct 280 IEVQTEG----MTPETGTYRWMAPEMIQHRAYNQKVDVYSFGIVLWELITGLLPF----- 330 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 Q V ++ RG R P+ C + +M CW+ RP F ++ Sbjct 331 ---------QNMTAVQAAFAVVNRGVRPTVPNDCLPVLSDIMTRCWDANPEVRPCFVEVV 381 Query 1167 PILKTVHEKYQGQA 1180 +L+ + A Sbjct 382 KLLEAAETEIMTTA 395 Score = 216 bits (549), Expect = 4e-60, Method: Composition-based stats. Identities = 60/303 (20%), Positives = 116/303 (38%), Gaps = 49/303 (16%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 T L+ +D +++ QG +Y+G E Sbjct 114 TEGLTNYDEWTIDLRKLNMGPAFAQGAFGKLYKGTYNGED-------------------- 153 Query 633 RGQELRVVLKVLDPSHHDIALAFYET------ASLMSQVSHTHLAFVHGVCVRGPENIMV 686 V +K+L+ + A + S+++ + H ++ G C + +V Sbjct 154 ------VAIKILERPENSPEKAQFMEQQFQQEVSMLANLKHPNIVRFIGACRKPMVWCIV 207 Query 687 TEYVEHGPLDVWL-RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 TEY + G + +L RR+ VP+ + A +A ++Y+ +N +H ++ N+L++ Sbjct 208 TEYAKGGSVRQFLTRRQNRAVPLKLAVKQALDVARGMAYVHGRNFIHRDLKSDNLLIS-- 265 Query 746 GLAEGTSPFIKLSDPGVGLGALSREER---VERIPWLAPECLPGGANSLSTAMDKWGFGA 802 IK++D GV + E W+APE + A + +D + FG Sbjct 266 -----ADKSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRA--YNQKVDVYSFGI 318 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQR---QHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859 L E+ G P Q+ + + + +P P L+ + ++C P RP F Sbjct 319 VLWELI-TGLLPFQNMTAVQAAFAVVNRGVRPTVPNDCLPVLSDIMTRCWDANPEVRPCF 377 Query 860 RTI 862 + Sbjct 378 VEV 380 >sp|Q75ZY9|MET_CANLF Hepatocyte growth factor receptor OS=Canis lupus familiaris OX=9615 GN=MET PE=1 SV=1 Length=1382 Score = 271 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 89/285 (31%), Positives = 135/285 (47%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V ND AVK+L S + E I++ H Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW A RP+F L+ + + + G+ Sbjct 1304 LQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGE 1348 Score = 227 bits (579), Expect = 3e-59, Method: Composition-based stats. Identities = 63/328 (19%), Positives = 118/328 (36%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L +++ +K L+ Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1119 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C RPSF ++ ++ + + + Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D +G Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNIDG 1378 >sp|O49564|CRK27_ARATH Cysteine-rich receptor-like protein kinase 27 OS=Arabidopsis thaliana OX=3702 GN=CRK27 PE=3 SV=2 Length=642 Score = 260 bits (664), Expect = 3e-73, Method: Composition-based stats. Identities = 77/321 (24%), Positives = 132/321 (41%), Gaps = 16/321 (5%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 L+ + + + + + +GEG FG V + G +A Sbjct 305 LKENAENEFESTDSLHFDFETIRVATDDFSLTNKIGEGGFGVVYKG-----HLPDGLEIA 359 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 VK L G Q + +K E+ ++ L H++++K G + E+ LV E++P SL Sbjct 360 VKRLSIHSG-QGNAEFKTEVLLMTKLQHKNLVKLFGFSIKESER--LLVYEFIPNTSLDR 416 Query 989 YL----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGD 1041 +L + + + + G+ YLH IHRDL + NVLLD L KI D Sbjct 417 FLFDPIKQKQLDWEKRYNIIVGVSRGLLYLHEGSEFPIIHRDLKSSNVLLDEQMLPKISD 476 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FG+A+ + R + APE +F +DV+SFGV + E++T +S Sbjct 477 FGMARQFDFDNTQAVTRR-VVGTYGYMAPEYAMHGRFSVKTDVYSFGVLVLEIITGKRNS 535 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + +L A EL++ K + + +C + + RPT Sbjct 536 GLGLGEGTDLPTFAWQNWIEGTSMELIDPVLLQTHDKKESMQCLEIALSCVQENPTKRPT 595 Query 1162 FENLIPILKTVHEKYQGQAPS 1182 ++++ +L + E Q PS Sbjct 596 MDSVVSMLSSDSESRQLPKPS 616 Score = 225 bits (574), Expect = 3e-61, Method: Composition-based stats. Identities = 66/390 (17%), Positives = 126/390 (32%), Gaps = 63/390 (16%) Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562 +K P+ + G+S + L A+ + F + + + Sbjct 249 QKQPLSSHNNNTRRSDQGKSKDRSKTLIFAVVPIVAIILGLVFLFIY-LKRRRKKKTLKE 307 Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 S +L+ RV + + + +G+G VY+G L Sbjct 308 NAENEFESTDSLHF-DFETIRVATDDFSLTNKIGEGGFGVVYKGHLPDG----------- 355 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 L + +K L F LM+++ H +L + G ++ E Sbjct 356 --------------LEIAVKRLSIHSGQGNAEFKTEVLLMTKLQHKNLVKLFGFSIKESE 401 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCG 737 ++V E++ + LD +L + W + + ++ L YL + ++H ++ Sbjct 402 RLLVYEFIPNTSLDRFLFDPIKQKQLDWEKRYNIIVGVSRGLLYLHEGSEFPIIHRDLKS 461 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSL 791 N+LL L K+SD G+ + V ++APE G Sbjct 462 SNVLLDEQMLP-------KISDFGMARQFDFDNTQAVTRRVVGTYGYMAPEYAMHG--RF 512 Query 792 STAMDKWGFGATLLEICFDGE-----------APLQSRSPS-EKEHFYQRQHRLPEPS-- 837 S D + FG +LEI P + E L + Sbjct 513 SVKTDVYSFGVLVLEIITGKRNSGLGLGEGTDLPTFAWQNWIEGTSMELIDPVLLQTHDK 572 Query 838 --CPQLATLTSQCLTYEPTQRPSFRTILRD 865 Q + C+ PT+RP+ +++ Sbjct 573 KESMQCLEIALSCVQENPTKRPTMDSVVSM 602 >sp|Q2QLA9|MET_HORSE Hepatocyte growth factor receptor OS=Equus caballus OX=9796 GN=MET PE=3 SV=1 Length=1381 Score = 271 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 89/285 (31%), Positives = 136/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V ND AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1256 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1303 LQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1347 Score = 228 bits (580), Expect = 2e-59, Method: Composition-based stats. Identities = 63/328 (19%), Positives = 119/328 (36%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L +++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D +G Sbjct 1350 VHVNATYVNVKCVAPYPSLLSSQDNVDG 1377 >sp|Q54RB7|SHKA_DICDI Dual specificity protein kinase shkA OS=Dictyostelium discoideum OX=44689 GN=shkA PE=2 SV=1 Length=527 Score = 256 bits (655), Expect = 4e-73, Method: Composition-based stats. Identities = 69/274 (25%), Positives = 124/274 (45%), Gaps = 25/274 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V + VAVK + + + +++E+ I+ ++H +I+ + Sbjct 51 LGDGSFGTVYKGRCRLKD------VAVKVMLKQVDQKTLTDFRKEVAIMSKIFHPNIVLF 104 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH-- 1018 G C L + E + G+L L P + L + A+ G+ +LH+ + Sbjct 105 LGACTS-TPGKLMICTELM-KGNLESLLLDPMVKLPLITRMRMAKDAALGVLWLHSSNPV 162 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +IHRDL N+L+D + VK+ DFGL++ G ++ W APE L+ F Sbjct 163 FIHRDLKTSNLLVDANLTVKVCDFGLSQIKQRGENLKDGQDGAKGTPLWMAPEVLQGRLF 222 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 +DV+SFG+ L+++ T + + + + E+ R PD Sbjct 223 NEKADVYSFGLVLWQIFTRQELF-------------PEFDNFFKFVAAICEKQLRPSIPD 269 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 CP + L++ CW+ RP+FE ++ L+ + Sbjct 270 DCPKSLKELIQKCWDPNPEVRPSFEGIVSELEEI 303 Score = 228 bits (582), Expect = 2e-63, Method: Composition-based stats. Identities = 66/338 (20%), Positives = 117/338 (35%), Gaps = 50/338 (15%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + + EIT S LG G+ VY+GR R++ V + Sbjct 38 PEISETEITTESILGDGSFGTVYKGRCRLKD--------------------------VAV 71 Query 642 K-VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV-RGPENIMVTEYVEHGPLDVWL 699 K +L F + ++MS++ H ++ G C + ++ TE ++ G L+ L Sbjct 72 KVMLKQVDQKTLTDFRKEVAIMSKIFHPNIVLFLGACTSTPGKLMICTELMK-GNLESLL 130 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKL 757 +P+ +M +A+ A + +L + N +H ++ N+L+ + +K+ Sbjct 131 LDPMVKLPLITRMRMAKDAALGVLWLHSSNPVFIHRDLKTSNLLVD-------ANLTVKV 183 Query 758 SDPGVGLGALSREE-------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 D G+ E W+APE L G + D + FG L +I Sbjct 184 CDFGLSQIKQRGENLKDGQDGAKGTPLWMAPEVLQGRL--FNEKADVYSFGLVLWQIFTR 241 Query 811 GE-APLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 E P ++Q R +P+ L L +C P RPSF I+ +L Sbjct 242 QELFPEFDNFFKFVAAICEKQLRPSIPDDCPKSLKELIQKCWDPNPEVRPSFEGIVSELE 301 Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 + + I Sbjct 302 EIIIDCCIPDEYGAILWKNHFKHENEANWKDFINVFSN 339 Score = 38.1 bits (87), Expect = 0.58, Method: Composition-based stats. Identities = 12/64 (19%), Positives = 27/64 (42%), Gaps = 2/64 (3%) Query 450 GIHGPLLEPFVQAKLRPE-DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLR-KFPI 507 HG + + +LR + +G +L+ +STS ++ ++ + R + KF + Sbjct 424 WFHGDISTSESENRLRQKPEGTFLVRFSTSEYGAYTISKVSKNGGISHQRIHRPQGKFQV 483 Query 508 EQQD 511 Sbjct 484 NNSK 487 >sp|F4JEQ2|PBL23_ARATH Probable serine/threonine-protein kinase PBL23 OS=Arabidopsis thaliana OX=3702 GN=PBL23 PE=2 SV=1 Length=386 Score = 251 bits (642), Expect = 4e-73, Method: Composition-based stats. Identities = 80/301 (27%), Positives = 126/301 (42%), Gaps = 19/301 (6%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 + LGEG FG+V + ++VAVK L + G Q Sbjct 68 HIFTFRELCVATKNFNPDNQLGEGGFGRVYKGQIETPE----QVVAVKQLDRN-GYQGNR 122 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIG 996 + E+ +L L+H++++ G C D ++ LV EY+ GSL D+L + + Sbjct 123 EFLVEVMMLSLLHHQNLVNLVGYCADGDQR--ILVYEYMQNGSLEDHLLELARNKKKPLD 180 Query 997 LAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + A G+ YLH I+RD A N+LLD + K+ DFGLAK P G E Sbjct 181 WDTRMKVAAGAARGLEYLHETADPPVIYRDFKASNILLDEEFNPKLSDFGLAKVGPTGGE 240 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELI 1112 + V + APE + SDV+SFGV E++T + PT+ L+ Sbjct 241 TH-VSTRVMGTYGYCAPEYALTGQLTVKSDVYSFGVVFLEMITGRRVIDTTKPTEEQNLV 299 Query 1113 GIAQGQMTVLR-LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 A R T + + P K + + C + EA+ RP +++ L+ Sbjct 300 TWASPLFKDRRKFTLMADPLLEGKYPIKGLYQALAVAAMCLQEEAATRPMMSDVVTALEY 359 Query 1172 V 1172 + Sbjct 360 L 360 Score = 231 bits (589), Expect = 8e-66, Method: Composition-based stats. Identities = 69/318 (22%), Positives = 113/318 (36%), Gaps = 66/318 (21%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V K + LG+G VY+G++ E V +K Sbjct 77 VATKNFNPDNQLGEGGFGRVYKGQIETP------------------------EQVVAVKQ 112 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---- 699 LD + + F ++S + H +L + G C G + I+V EY+++G L+ L Sbjct 113 LDRNGYQGNREFLVEVMMLSLLHHQNLVNLVGYCADGDQRILVYEYMQNGSLEDHLLELA 172 Query 700 RRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIK 756 R ++ + +M VA A L YL +++ + NILL K Sbjct 173 RNKKKPLDWDTRMKVAAGAARGLEYLHETADPPVIYRDFKASNILLDEEFNP-------K 225 Query 757 LSDPGVGL-GALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 LSD G+ G E V + APE G L+ D + FG LE+ Sbjct 226 LSDFGLAKVGPTGGETHVSTRVMGTYGYCAPEYALTG--QLTVKSDVYSFGVVFLEMI-T 282 Query 811 GEAPLQSRSPSEKEHFYQR-------------------QHRLPEPSCPQLATLTSQCLTY 851 G + + P+E+++ + + P Q + + CL Sbjct 283 GRRVIDTTKPTEEQNLVTWASPLFKDRRKFTLMADPLLEGKYPIKGLYQALAVAAMCLQE 342 Query 852 EPTQRPSFRTILRDLTRL 869 E RP ++ L L Sbjct 343 EAATRPMMSDVVTALEYL 360 >sp|Q769I5|MET_BOVIN Hepatocyte growth factor receptor OS=Bos taurus OX=9913 GN=MET PE=2 SV=1 Length=1384 Score = 271 bits (692), Expect = 4e-73, Method: Composition-based stats. Identities = 90/285 (32%), Positives = 136/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V ND AVK+L S + E I++ H Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLA 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ V + Y + PV W A E L+ Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQ 1257 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISVIFSTFIGE 1348 Score = 229 bits (583), Expect = 9e-60, Method: Composition-based stats. Identities = 63/328 (19%), Positives = 118/328 (36%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L +++ +K L+ Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1119 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMEYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDVYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISVIFSTFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D G Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNVSG 1378 >sp|Q2QLE0|MET_PIG Hepatocyte growth factor receptor OS=Sus scrofa OX=9823 GN=MET PE=2 SV=1 Length=1381 Score = 270 bits (691), Expect = 4e-73, Method: Composition-based stats. Identities = 90/285 (32%), Positives = 135/285 (47%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V ND AVK+L S + E I++ H Sbjct 1079 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1138 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1196 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ V + Y + PV W A E L+ Sbjct 1197 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQ 1256 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1257 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1302 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW A RP+F L+ + + + G+ Sbjct 1303 LQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGE 1347 Score = 228 bits (580), Expect = 2e-59, Method: Composition-based stats. Identities = 63/328 (19%), Positives = 118/328 (36%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L +++ +K L+ Sbjct 1080 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1118 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1119 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1178 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1179 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDVYD 1231 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1232 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1289 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C RPSF ++ ++ + + + Sbjct 1290 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPRAELRPSFSELVSRISAIFSTFIGEHY 1349 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D +G Sbjct 1350 VHVNATYVNVKCVAPYPSLLSSQDNVDG 1377 >sp|Q09YI9|MET_SHEEP Hepatocyte growth factor receptor OS=Ovis aries OX=9940 GN=MET PE=3 SV=1 Length=1384 Score = 270 bits (691), Expect = 5e-73, Method: Composition-based stats. Identities = 90/285 (32%), Positives = 136/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V ND AVK+L S + E I++ H Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLA 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ V + Y + PV W A E L+ Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQ 1257 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRIAAIFSAFIGE 1348 Score = 228 bits (582), Expect = 1e-59, Method: Composition-based stats. Identities = 62/328 (19%), Positives = 117/328 (36%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L +++ +K L+ Sbjct 1081 FNEVIGRGHFGCVYHGTLLDND---------------------DKKIHCAVKSLNRITDI 1119 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMEYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDVYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ + + + + Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRIAAIFSAFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L ++ G Sbjct 1351 VHVNATYVNVRCVAPYPSLLSSQENVSG 1378 >sp|O49839|PBL2_ARATH Probable serine/threonine-protein kinase PBL2 OS=Arabidopsis thaliana OX=3702 GN=PBL2 PE=1 SV=1 Length=426 Score = 253 bits (645), Expect = 5e-73, Method: Composition-based stats. Identities = 87/283 (31%), Positives = 129/283 (46%), Gaps = 16/283 (6%) Query 903 LGEGHFGKVSLYCYD-----PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 LGEG FG V D + G+G +VAVK LK + G Q W E++ L L H Sbjct 92 LGEGGFGCVFKGWIDQTSLTASRPGSGIVVAVKQLKPE-GFQGHKEWLTEVNYLGQLSHP 150 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYL 1014 +++ G C + GE L LV E++P GSL ++L R + A + A +G+ +L Sbjct 151 NLVLLVGYCAE-GENRL-LVYEFMPKGSLENHLFRRGAQPLTWAIRMKVAVGAAKGLTFL 208 Query 1015 HAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 H I+RD A N+LLD D K+ DFGLAKA P G + V + APE Sbjct 209 HEAKSQVIYRDFKAANILLDADFNAKLSDFGLAKAGPTGDNTH-VSTKVIGTHGYAAPEY 267 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQM-TVLRLTELLER 1130 + + SDV+SFGV L EL++ + S L+ A + +L +++ Sbjct 268 VATGRLTAKSDVYSFGVVLLELISGRRAMDNSNGGNEYSLVDWATPYLGDKRKLFRIMDT 327 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 P K +L C +A RP ++ L+ + Sbjct 328 KLGGQYPQKGAFTAANLALQCLNPDAKLRPKMSEVLVTLEQLE 370 Score = 239 bits (611), Expect = 2e-68, Method: Composition-based stats. Identities = 79/359 (22%), Positives = 128/359 (36%), Gaps = 55/359 (15%) Query 561 LIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618 L +R + NL +F+ + K Q + LG+G V++G + Sbjct 56 LPTLRTEGEILSSPNLKAFTFNELKNATKNFRQDNLLGEGGFGCVFKGWI---------- 105 Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678 D+ L R G + V +K L P + + + Q+SH +L + G C Sbjct 106 ----DQTSLTASRP-GSGIVVAVKQLKPEGFQGHKEWLTEVNYLGQLSHPNLVLLVGYCA 160 Query 679 RGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN--KNLVHGN 734 G ++V E++ G L+ L R RG P+ W +M VA A L++L +++ + Sbjct 161 EGENRLLVYEFMPKGSLENHLFR-RGAQPLTWAIRMKVAVGAAKGLTFLHEAKSQVIYRD 219 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGA 788 NILL KLSD G+ + + + + APE + G Sbjct 220 FKAANILLD-------ADFNAKLSDFGLAKAGPTGDNTHVSTKVIGTHGYAAPEYVATG- 271 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR------------------Q 830 L+ D + FG LLE+ A S +E Sbjct 272 -RLTAKSDVYSFGVVLLELISGRRAMDNSNGGNEYSLVDWATPYLGDKRKLFRIMDTKLG 330 Query 831 HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 + P+ A L QCL + RP +L L +L+ +SP Sbjct 331 GQYPQKGAFTAANLALQCLNPDAKLRPKMSEVLVTLEQLESVAKPGTKHTQMESPRFHH 389 >sp|Q07E37|MET_NEONE Hepatocyte growth factor receptor OS=Neofelis nebulosa OX=61452 GN=MET PE=3 SV=1 Length=1382 Score = 270 bits (690), Expect = 5e-73, Method: Composition-based stats. Identities = 88/285 (31%), Positives = 137/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V ++D AVK+L S + E I++ H Sbjct 1080 HFNEVIGRGHFGCVYHGTLLDSDDK-KIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348 Score = 226 bits (577), Expect = 4e-59, Method: Composition-based stats. Identities = 63/328 (19%), Positives = 119/328 (36%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L +++ +K L+ Sbjct 1081 FNEVIGRGHFGCVYHGTLLDSD---------------------DKKIHCAVKSLNRITDI 1119 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D +G Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNIDG 1378 >sp|A0M8S8|MET_FELCA Hepatocyte growth factor receptor OS=Felis catus OX=9685 GN=MET PE=3 SV=1 Length=1382 Score = 270 bits (690), Expect = 5e-73, Method: Composition-based stats. Identities = 88/285 (31%), Positives = 137/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V ++D AVK+L S + E I++ H Sbjct 1080 HFNEVIGRGHFGCVYHGTLLDSDDK-KIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRRL 1303 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1304 LQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGE 1348 Score = 226 bits (577), Expect = 4e-59, Method: Composition-based stats. Identities = 63/328 (19%), Positives = 119/328 (36%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L +++ +K L+ Sbjct 1081 FNEVIGRGHFGCVYHGTLLDSD---------------------DKKIHCAVKSLNRITDI 1119 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D +G Sbjct 1351 VHVNATYVNVKCVAPYPSLLSSQDNIDG 1378 >sp|A1X150|MET_ECHTE Hepatocyte growth factor receptor OS=Echinops telfairi OX=9371 GN=MET PE=3 SV=1 Length=1380 Score = 270 bits (690), Expect = 5e-73, Method: Composition-based stats. Identities = 93/286 (33%), Positives = 139/286 (49%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V ND AVK+L S + E I++ H Sbjct 1078 HFNEVIGRGHFGCVYHGTLLD-NDDRKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1136 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ HS + L+ F Q+ +GM YL Sbjct 1137 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHSPTVKDLIGFGLQVAKGMKYLA 1195 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073 ++ ++HRDLAARN +LD VK+ DFGLA+ + + EYY V + PV W A E L Sbjct 1196 SKKFVHRDLAARNCMLDGKFTVKVADFGLARDMYD-KEYYSVHNKTGAKLPVKWMALESL 1254 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV L+EL+T + +T L +G R Sbjct 1255 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1300 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1301 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFTELVSRISAIFSTFIGE 1346 Score = 227 bits (578), Expect = 4e-59, Method: Composition-based stats. Identities = 63/328 (19%), Positives = 117/328 (36%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L +++ +K L+ Sbjct 1079 FNEVIGRGHFGCVYHGTLLDND---------------------DRKIHCAVKSLNRITDI 1117 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + Sbjct 1118 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHSPTV 1177 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1178 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLD-------GKFTVKVADFGLARDMYD 1230 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1231 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1288 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1289 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFTELVSRISAIFSTFIGEHY 1348 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L D +G Sbjct 1349 VHVNATYVNVKCVAPYPSLLSSHDTVDG 1376 >sp|Q61006|MUSK_MOUSE Muscle, skeletal receptor tyrosine-protein kinase OS=Mus musculus OX=10090 GN=Musk PE=1 SV=1 Length=868 Score = 264 bits (675), Expect = 6e-73, Method: Composition-based stats. Identities = 86/336 (26%), Positives = 149/336 (44%), Gaps = 43/336 (13%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND-GTGEMVAV 929 N +P + + ++ +RD+GEG FG+V MVAV Sbjct 548 HPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAV 607 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K LK + ++ +++E ++ + +I+K G C K + L+ EY+ G L ++ Sbjct 608 KMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVG--KPMCLLFEYMAYGDLNEF 665 Query 990 LPR-------------------------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDL 1024 L + A+ L A+Q+ GMAYL + ++HRDL Sbjct 666 LRSMSPHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDL 725 Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084 A RN L+ +VKI DFGL++ + +YY+ + P+ W PE + ++ SDV Sbjct 726 ATRNCLVGETMVVKIADFGLSRNIY-SADYYKADGNDAIPIRWMPPESIFYNRYTTESDV 784 Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144 W++GV L+E+ ++ M + + G L P+ CP E+ Sbjct 785 WAYGVVLWEIFSYGLQ--------------PYYGMAHEEVIYYVRDGNILACPENCPLEL 830 Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180 Y+LM+ CW + RP+F ++ IL+ + E+ +G Sbjct 831 YNLMRLCWSKLPADRPSFCSIHRILQRMCERAEGTV 866 Score = 244 bits (623), Expect = 4e-66, Method: Composition-based stats. Identities = 71/317 (22%), Positives = 127/317 (40%), Gaps = 60/317 (19%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + I + +G+G V++ R +P V +K+L Sbjct 570 PRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTM-------------------VAVKML 610 Query 645 DPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--- 700 D+ F A+LM++ + ++ + GVC G ++ EY+ +G L+ +LR Sbjct 611 KEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMS 670 Query 701 ------------------RERGHVPMA--WKMVVAQQLASALSYLENKNLVHGNVCGRNI 740 G P++ ++ +A+Q+A+ ++YL + VH ++ RN Sbjct 671 PHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNC 730 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLSTA 794 L+ G + +K++D G+ S + I W+ PE + N +T Sbjct 731 LV-------GETMVVKIADFGLSRNIYSADYYKADGNDAIPIRWMPPESIF--YNRYTTE 781 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYE 852 D W +G L EI G P + E ++ + + L PE +L L C + Sbjct 782 SDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILACPENCPLELYNLMRLCWSKL 841 Query 853 PTQRPSFRTILRDLTRL 869 P RPSF +I R L R+ Sbjct 842 PADRPSFCSIHRILQRM 858 >sp|Q05688|IGF1R_BOVIN Insulin-like growth factor 1 receptor (Fragment) OS=Bos taurus OX=9913 GN=IGF1R PE=2 SV=1 Length=640 Score = 259 bits (662), Expect = 6e-73, Method: Composition-based stats. Identities = 92/312 (29%), Positives = 144/312 (46%), Gaps = 29/312 (9%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALK 933 D D + + R+LG+G FG V E VA+K + Sbjct 250 NPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVN 309 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR- 992 + R + E +++ H+++ G QG+ +L ++ME + G L+ YL Sbjct 310 EAASMRERIEFLNEASVMKEFNCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSL 367 Query 993 ----------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 L++++ A +I +GMAYL+A ++HRDLAARN ++ D VKIGDF Sbjct 368 RPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDF 427 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 G+ + + E +YYR G PV W +PE LK+ F SDVWSFGV L+E+ T Sbjct 428 GMTRDIYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIAT------ 480 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 L ++ ++ + G L +PD CP ++ LM+ CW+ RP+F Sbjct 481 --------LAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSF 532 Query 1163 ENLIPILKTVHE 1174 +I +K E Sbjct 533 LEIISSVKDEME 544 Score = 253 bits (647), Expect = 6e-71, Method: Composition-based stats. Identities = 100/530 (19%), Positives = 181/530 (34%), Gaps = 87/530 (16%) Query 425 RLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLI 484 +L +S+++ P D I GP+ RPE+ ++L +P LI Sbjct 85 KLGCSASNFVFARTMPA----EGADDIPGPVTWE-----PRPENSIFLKWPEPENPNGLI 135 Query 485 LTVAQR-SQAPDGMQSL----RLRKFPIEQQD-----------GAFVLEGWGR------- 521 L + + + RK+ + + A L G G Sbjct 136 LMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFF 195 Query 522 ------SFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLN 575 ++ + L AL +L + + + + A +P + Sbjct 196 YVQAKTTYENFIHLMIALPIAVLLIVGGLVIMLYVFHRKRNSSRLGNGVLYASVNPEYFS 255 Query 576 LSQL---SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 + + V +++IT LGQG+ VYEG + +P Sbjct 256 AADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEP---------------- 299 Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 E RV +K ++ + + F AS+M + + H+ + GV +G +++ E + Sbjct 300 ---ETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMT 356 Query 692 HGPLDVWLRRERGHV---------PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 G L +LR R + ++ + +A ++A ++YL VH ++ RN ++ Sbjct 357 RGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV 416 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMD 796 A +K+ D G+ + + + W++PE L G +T D Sbjct 417 AE-------DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTHSD 467 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854 W FG L EI E P Q S + F L P+ L L C Y P Sbjct 468 VWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPK 527 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 RPSF I+ + +V + + + + Sbjct 528 MRPSFLEIISSVKDEMEAGFREVSFYYSEENKPPEPEELDLEPENMESVP 577 >sp|Q9FGB1|CBC2_ARATH Serine/threonine-protein kinase 52 OS=Arabidopsis thaliana OX=3702 GN=CBC2 PE=1 SV=1 Length=385 Score = 251 bits (641), Expect = 6e-73, Method: Composition-based stats. Identities = 82/318 (26%), Positives = 131/318 (41%), Gaps = 52/318 (16%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--------- 940 L L G FG V YD G+ VAVK L D G + Sbjct 75 WEIDPSKLIIKTVLARGTFGTVHRGIYD------GQDVAVKLL--DWGEEGHRSEAEIVS 126 Query 941 -RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL--------------QLVMEYVPLGS 985 R+ + QE+ + L H ++ K+ G L +V+EY+P G+ Sbjct 127 LRADFAQEVAVWHKLDHPNVTKFIGATMGASGLQLQTESGPLAMPNNICCVVVEYLPGGA 186 Query 986 LRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 L+ YL R + ++ A + G++YLH+Q +HRD+ N+LLD R VKI DF Sbjct 187 LKSYLIKNRRRKLTFKIVVQLALDLARGLSYLHSQKIVHRDVKTENMLLDKTRTVKIADF 246 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 G+A+ + + APE L + DV+SFG+ L+E+ +C Sbjct 247 GVARVEASNPND---MTGETGTLGYMAPEVLNGNPYNRKCDVYSFGICLWEI--YCCDMP 301 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 P F E+ + ++ + R P CP + +MK CW+ RP Sbjct 302 YPDLTFSEV------------TSAVVRQNLRPDIPRCCPSALAAVMKRCWDANPDKRPEM 349 Query 1163 ENLIPILKTVHEKYQGQA 1180 + ++P+L+++ G Sbjct 350 DEVVPMLESIDTTKGGGM 367 Score = 212 bits (539), Expect = 4e-59, Method: Composition-based stats. Identities = 76/397 (19%), Positives = 136/397 (34%), Gaps = 76/397 (19%) Query 530 GAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSF-------H 582 +L L R +L + +T+ + I A +SP TLN Sbjct 16 LKSLDEQLERHLSRALTLEKNKKKDEEDTTAVAIGGSASSSPVTLNGGGFVGKRKQRLEW 75 Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 +D ++ + L +GT V+ G + G+D V +K Sbjct 76 EIDPSKLIIKTVLARGTFGTVHRG--------------------IYDGQD------VAVK 109 Query 643 VLDPSHH---------DIALAFYETASLMSQVSHTHLAFVHGVC---------VRGPEN- 683 +LD + F + ++ ++ H ++ G Sbjct 110 LLDWGEEGHRSEAEIVSLRADFAQEVAVWHKLDHPNVTKFIGATMGASGLQLQTESGPLA 169 Query 684 ------IMVTEYVEHGPLDVWL-RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736 +V EY+ G L +L + R + + +A LA LSYL ++ +VH +V Sbjct 170 MPNNICCVVVEYLPGGALKSYLIKNRRRKLTFKIVVQLALDLARGLSYLHSQKIVHRDVK 229 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLS 792 N+LL + + +K++D GV + ++APE L G N + Sbjct 230 TENMLLDK-------TRTVKIADFGVARVEASNPNDMTGETGTLGYMAPEVLNG--NPYN 280 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH---RLPEPSCPQLATLTSQCL 849 D + FG L EI + P + SE RQ+ +P LA + +C Sbjct 281 RKCDVYSFGICLWEIYCC-DMPYPDLTFSEVTSAVVRQNLRPDIPRCCPSALAAVMKRCW 339 Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 P +RP ++ L + ++ + Sbjct 340 DANPDKRPEMDEVVPMLESIDTTKGGGMIPNDQQQGC 376 >sp|Q14289|FAK2_HUMAN Protein-tyrosine kinase 2-beta OS=Homo sapiens OX=9606 GN=PTK2B PE=1 SV=2 Length=1009 Score = 266 bits (681), Expect = 6e-73, Method: Composition-based stats. Identities = 97/278 (35%), Positives = 147/278 (53%), Gaps = 22/278 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG+V Y + G VAVK K DC ++ + E I++ L H HI+K Sbjct 431 LGEGFFGEVYEGVYTN-HKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKL 489 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHYI 1020 G E E+ ++ME P G L YL R+ L L+L++ QIC+ MAYL + + + Sbjct 490 IGIIE---EEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCV 546 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+A RN+L+ + VK+GDFGL++ + E +YY+ P+ W +PE + +F Sbjct 547 HRDIAVRNILVASPECVKLGDFGLSRYI-EDEDYYKASVT-RLPIKWMSPESINFRRFTT 604 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ASDVW F V ++E+L+ + + +LE+G+RLP+PD C Sbjct 605 ASDVWMFAVCMWEILSFGKQ--------------PFFWLENKDVIGVLEKGDRLPKPDLC 650 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P +Y LM CW+ + S RP F L+ L V++ + Sbjct 651 PPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKD 688 Score = 244 bits (622), Expect = 2e-65, Method: Composition-based stats. Identities = 72/331 (22%), Positives = 132/331 (40%), Gaps = 39/331 (12%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 A TL + + ++++ LG+G VYEG Sbjct 403 AEIPDETLRRPGGPQYGIAREDVVLNRILGEGFFGEVYEG-------------------- 442 Query 627 LVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 V +G+++ V +K D F A +M + H H+ + G+ + + Sbjct 443 -VYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGI-IEEEPTWI 500 Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 + E +G L +L R + + + ++ + Q+ A++YLE+ N VH ++ RNIL+A Sbjct 501 IMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVA-- 558 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGF 800 + +KL D G+ + I W++PE + +TA D W F Sbjct 559 -----SPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESI--NFRRFTTASDVWMF 611 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPS 858 + EI G+ P + ++ RLP+P P L TL ++C Y+P+ RP Sbjct 612 AVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPR 671 Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 F ++ L+ + + ++ P Sbjct 672 FTELVCSLSDVYQMEKDIAMEQERNARYRTP 702 >sp|Q108U6|MET_LOXAF Hepatocyte growth factor receptor OS=Loxodonta africana OX=9785 GN=MET PE=3 SV=1 Length=1382 Score = 270 bits (689), Expect = 7e-73, Method: Composition-based stats. Identities = 92/286 (32%), Positives = 138/286 (48%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V N AVK+L S + E I++ H Sbjct 1080 HFNEVIGRGHFGCVYHGTLLD-NGDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLA 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV--REDGDSPVFWYAPECL 1073 ++ ++HRDLAARN +LD VK+ DFGLA+ V + EYY V + PV W A E L Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYD-KEYYSVHNKTGAKLPVKWMALESL 1256 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV L+EL+T + +T L +G R Sbjct 1257 QTQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGRR 1302 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L +P+ CP +Y +M CW +A RP+F L+ + + + G+ Sbjct 1303 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGE 1348 Score = 230 bits (586), Expect = 4e-60, Method: Composition-based stats. Identities = 61/317 (19%), Positives = 115/317 (36%), Gaps = 42/317 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G VY G L G +++ +K L+ Sbjct 1081 FNEVIGRGHFGCVYHGTLLDNG---------------------DKKIHCAVKSLNRITDI 1119 Query 651 IAL-AFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 GEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDVYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPSF ++ ++ + + + Sbjct 1291 FDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKR 895 + + V Sbjct 1351 VHVNTTYVNVKCVAPYP 1367 >sp|Q8GWJ7|CRK19_ARATH Cysteine-rich receptor-like protein kinase 19 OS=Arabidopsis thaliana OX=3702 GN=CRK19 PE=1 SV=2 Length=645 Score = 259 bits (661), Expect = 7e-73, Method: Composition-based stats. Identities = 77/286 (27%), Positives = 120/286 (42%), Gaps = 18/286 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 I LG+G FG+V +G VAVK L G Q ++ E+ ++ L Sbjct 324 NCFLPINKLGQGGFGEVYKGTL-----SSGLQVAVKRLSKTSG-QGEKEFENEVVVVAKL 377 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEG 1010 H +++K G C + EK LV E+VP SL +L + + + I G Sbjct 378 QHRNLVKLLGYCLEGEEK--ILVYEFVPNKSLDHFLFDSTMKMKLDWTRRYKIIGGIARG 435 Query 1011 MAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH IHRDL A N+LLD+D KI DFG+A+ R + Sbjct 436 ILYLHQDSRLTIIHRDLKAGNILLDDDMNPKIADFGMARIFGMDQTEAMTRR-VVGTYGY 494 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLT 1125 +PE +F SDV+SFGV + E+++ +S L+ + + Sbjct 495 MSPEYAMYGQFSMKSDVYSFGVLVLEIISGMKNSSLYQMDESVGNLVTYTWRLWSNGSPS 554 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 EL++ H+ C + +A RPT +++ +L T Sbjct 555 ELVDPSFGDNYQTSEITRCIHIALLCVQEDAEDRPTMSSIVQMLTT 600 Score = 236 bits (602), Expect = 6e-65, Method: Composition-based stats. Identities = 59/324 (18%), Positives = 110/324 (34%), Gaps = 65/324 (20%) Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 T Q F ++ ++ LGQG VY+G L Sbjct 308 TAGSLQFDFKAIEAATNCFLPINKLGQGGFGEVYKGTLSSG------------------- 348 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 L+V +K L + F +++++ H +L + G C+ G E I+V E+V Sbjct 349 ------LQVAVKRLSKTSGQGEKEFENEVVVVAKLQHRNLVKLLGYCLEGEEKILVYEFV 402 Query 691 EHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745 + LD +L + + W + + +A + YL + ++H ++ NILL Sbjct 403 PNKSLDHFLFDSTMKMKLDWTRRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNILLD-- 460 Query 746 GLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWG 799 K++D G+ + V +++PE G S D + Sbjct 461 -----DDMNPKIADFGMARIFGMDQTEAMTRRVVGTYGYMSPEYAMYG--QFSMKSDVYS 513 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------------QL 841 FG +LEI + + + RL P + Sbjct 514 FGVLVLEIISGMKNSSLYQMDESVGNLVTYTWRLWSNGSPSELVDPSFGDNYQTSEITRC 573 Query 842 ATLTSQCLTYEPTQRPSFRTILRD 865 + C+ + RP+ +I++ Sbjct 574 IHIALLCVQEDAEDRPTMSSIVQM 597 >sp|Q9SSA4|CBC1_ARATH Serine/threonine-protein kinase 54 OS=Arabidopsis thaliana OX=3702 GN=CBC1 PE=1 SV=1 Length=411 Score = 251 bits (642), Expect = 8e-73, Method: Composition-based stats. Identities = 79/318 (25%), Positives = 131/318 (41%), Gaps = 52/318 (16%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--------- 940 L + G FG V YD G+ VAVK L D G + Sbjct 101 WEIDPSKLIIKSVIARGTFGTVHRGIYD------GQDVAVKLL--DWGEEGHRSDAEIAS 152 Query 941 -RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL--------------QLVMEYVPLGS 985 R+ + QE+ + L H ++ K+ G E S+ +V+EY P G+ Sbjct 153 LRAAFTQEVAVWHKLDHPNVTKFIGAAMGTSEMSIQTENGQMGMPSNVCCVVVEYCPGGA 212 Query 986 LRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 L+ +L R + ++ + + G++YLH+Q +HRD+ N+LLD R +KI DF Sbjct 213 LKSFLIKTRRRKLAFKVVIQLSLDLARGLSYLHSQKIVHRDVKTENMLLDKSRTLKIADF 272 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 G+A+ + + APE L + DV+SFG+ L+E+ +C Sbjct 273 GVARLEASNPND---MTGETGTLGYMAPEVLNGSPYNRKCDVYSFGICLWEI--YCCDMP 327 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 P F E+ + ++ + R P CP + ++MK CW+ RP Sbjct 328 YPDLSFSEV------------TSAVVRQNLRPEIPRCCPSSLANVMKRCWDANPEKRPEM 375 Query 1163 ENLIPILKTVHEKYQGQA 1180 E ++ +L+ + G Sbjct 376 EEVVAMLEAIDTSKGGGM 393 Score = 205 bits (522), Expect = 1e-56, Method: Composition-based stats. Identities = 66/339 (19%), Positives = 119/339 (35%), Gaps = 69/339 (20%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D ++ S + +GT V+ G + G+D V + Sbjct 101 WEIDPSKLIIKSVIARGTFGTVHRG--------------------IYDGQD------VAV 134 Query 642 KVLDPSHH---------DIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN--------- 683 K+LD + AF + ++ ++ H ++ G + E Sbjct 135 KLLDWGEEGHRSDAEIASLRAAFTQEVAVWHKLDHPNVTKFIGAAMGTSEMSIQTENGQM 194 Query 684 -------IMVTEYVEHGPLDVWL-RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNV 735 +V EY G L +L + R + + ++ LA LSYL ++ +VH +V Sbjct 195 GMPSNVCCVVVEYCPGGALKSFLIKTRRRKLAFKVVIQLSLDLARGLSYLHSQKIVHRDV 254 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSL 791 N+LL + S +K++D GV + ++APE L G + Sbjct 255 KTENMLLDK-------SRTLKIADFGVARLEASNPNDMTGETGTLGYMAPEVLNG--SPY 305 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH---RLPEPSCPQLATLTSQC 848 + D + FG L EI + P S SE RQ+ +P LA + +C Sbjct 306 NRKCDVYSFGICLWEIYCC-DMPYPDLSFSEVTSAVVRQNLRPEIPRCCPSSLANVMKRC 364 Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 P +RP ++ L + ++ + Sbjct 365 WDANPEKRPEMEEVVAMLEAIDTSKGGGMIPPDQQQGCF 403 >sp|Q62371|DDR2_MOUSE Discoidin domain-containing receptor 2 OS=Mus musculus OX=10090 GN=Ddr2 PE=1 SV=2 Length=854 Score = 263 bits (673), Expect = 8e-73, Method: Composition-based stats. Identities = 97/292 (33%), Positives = 144/292 (49%), Gaps = 35/292 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGE------------MVAVKALKADCGPQHRSGWKQEID 949 LGEG FG+V L + + +VAVK L+AD R+ + +EI Sbjct 568 KLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIK 627 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----------SIGLAQ 999 I+ L +II+ C E L ++ EY+ G L +L RH ++ A Sbjct 628 IMSRLKDPNIIRLLAVCI--TEDPLCMITEYMENGDLNQFLSRHEPLSSCSSDATVSYAN 685 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 L A QI GM YL + +++HRDLA RN L+ + +KI DFG+++ + G +YYR++ Sbjct 686 LKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSG-DYYRIQG 744 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 P+ W + E + KF ASDVW+FGVTL+E T C Q P L + + Sbjct 745 RAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC---QEQPYSQLSDEQVIENTG 801 Query 1120 TVLRLTELLERGER--LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 R ++G + LP+P CP VY LM +CW E RP+F+ + +L Sbjct 802 EFFR-----DQGRQIYLPQPALCPDSVYKLMLSCWRRETKHRPSFQEIHLLL 848 Score = 233 bits (593), Expect = 3e-62, Method: Composition-based stats. Identities = 74/315 (23%), Positives = 123/315 (39%), Gaps = 42/315 (13%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L+ ++ +K + LG+G V+ + E + + Sbjct 548 LSGKDVAVEEFPRKLLAFKEKLGEGQFGEVH--------LCEVEGMEKFKDKDFALDVSA 599 Query 634 GQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 Q + V +K+L + A F + +MS++ ++ + VC+ M+TEY+E+ Sbjct 600 NQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIRLLAVCITEDPLCMITEYMEN 659 Query 693 GPLDVWLRRERG--------HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 G L+ +L R V A +A Q+AS + YL + N VH ++ RN L+ Sbjct 660 GDLNQFLSRHEPLSSCSSDATVSYANLKFMATQIASGMKYLSSLNFVHRDLATRNCLV-- 717 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKW 798 G + IK++D G+ S + V I W++ E + G +TA D W Sbjct 718 -----GKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLG--KFTTASDVW 770 Query 799 GFGATLLEIC-FDGEAPLQSRSPSEKEH-----FYQRQHRL----PEPSCPQLATLTSQC 848 FG TL E F E P S + F + ++ P + L C Sbjct 771 AFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQIYLPQPALCPDSVYKLMLSC 830 Query 849 LTYEPTQRPSFRTIL 863 E RPSF+ I Sbjct 831 WRRETKHRPSFQEIH 845 >sp|Q9SYM9|Y1853_ARATH Receptor-like serine/threonine-protein kinase At1g78530 OS=Arabidopsis thaliana OX=3702 GN=At1g78530 PE=2 SV=1 Length=355 Score = 249 bits (637), Expect = 8e-73, Method: Composition-based stats. Identities = 76/307 (25%), Positives = 129/307 (42%), Gaps = 17/307 (6%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933 + + +S +SD + L LG G FG V D AVK L Sbjct 52 MVMFRSQLLNSVSSDMFMKKTHKLSNKDILGSGGFGTVYRLVID-----DSTTFAVKRLN 106 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-R 992 + R G+ +E++ + + H +I+ G L+ E +P GSL +L R Sbjct 107 RGTSERDR-GFHRELEAMADIKHRNIVTLHGYFTSPHYN--LLIYELMPNGSLDSFLHGR 163 Query 993 HSIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 ++ A A G++YLH H IHRD+ + N+LLD++ ++ DFGLA + Sbjct 164 KALDWASRYRIAVGAARGISYLHHDCIPHIIHRDIKSSNILLDHNMEARVSDFGLATLME 223 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF- 1108 + V + APE K DV+SFGV L ELLT + + Sbjct 224 PDKTH--VSTFVAGTFGYLAPEYFDTGKATMKGDVYSFGVVLLELLTGRKPTDDEFFEEG 281 Query 1109 LELIGIAQGQMTVLRLTELLERGERLP--RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 +L+ +G + R +++ R + ++ +V+ + C E E + RP ++ Sbjct 282 TKLVTWVKGVVRDQREEVVIDNRLRGSSVQENEEMNDVFGIAMMCLEPEPAIRPAMTEVV 341 Query 1167 PILKTVH 1173 +L+ + Sbjct 342 KLLEYIK 348 Score = 207 bits (526), Expect = 7e-58, Method: Composition-based stats. Identities = 64/338 (19%), Positives = 120/338 (36%), Gaps = 69/338 (20%) Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620 +++ R + + ++ H++ K+I LG G VY RL ++ S Sbjct 52 MVMFRSQLLNSVSSDMFMKKTHKLSNKDI-----LGSGGFGTVY--RLVIDDSTTF---- 100 Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680 +K L+ + F+ M+ + H ++ +HG Sbjct 101 -------------------AVKRLNRGTSERDRGFHRELEAMADIKHRNIVTLHGYFTSP 141 Query 681 PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCG 737 N+++ E + +G LD +L R + A + +A A +SYL + +++H ++ Sbjct 142 HYNLLIYELMPNGSLDSFLHG-RKALDWASRYRIAVGAARGISYLHHDCIPHIIHRDIKS 200 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLS 792 NILL + ++SD G+ + V +LAPE G ++ Sbjct 201 SNILLDH-------NMEARVSDFGLATLMEPDKTHVSTFVAGTFGYLAPEYFDTGKATM- 252 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR--------------QHRL----- 833 D + FG LLE+ G P E +RL Sbjct 253 -KGDVYSFGVVLLELL-TGRKPTDDEFFEEGTKLVTWVKGVVRDQREEVVIDNRLRGSSV 310 Query 834 -PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + + CL EP RP+ +++ L ++ Sbjct 311 QENEEMNDVFGIAMMCLEPEPAIRPAMTEVVKLLEYIK 348 >sp|Q9CAH1|Y1725_ARATH Putative receptor-like protein kinase At1g72540 OS=Arabidopsis thaliana OX=3702 GN=At1g72540 PE=2 SV=1 Length=450 Score = 253 bits (645), Expect = 9e-73, Method: Composition-based stats. Identities = 81/321 (25%), Positives = 135/321 (42%), Gaps = 15/321 (5%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG---E 925 + ++ ++ +N + + K LGEG FG+V D + TG + Sbjct 56 ISLNDFSNSFFINIHIFTYEELKTITQGFSKYNFLGEGGFGEVYKGFVDDSLK-TGLKDQ 114 Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 VAVKALK + G HR W E+ IL L H H++ G C + E+ LV EY+ G+ Sbjct 115 PVAVKALKREGGQGHRE-WLAEVIILGQLKHPHLVNLVGYCCEDDER--LLVYEYMERGN 171 Query 986 LRDYLPRH---SIGLAQLLLFAQQICEGMAYLH--AQHYIHRDLAARNVLLDNDRLVKIG 1040 L D+L + ++ + +G+ +LH + I+RD N+LL +D K+ Sbjct 172 LEDHLFQKYGGALPWLTRVKILLGAAKGLEFLHKQEKPVIYRDFKPSNILLSSDFSSKLS 231 Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT-HCD 1099 DFGLA E + + + APE + SDV+SFGV L E+LT Sbjct 232 DFGLATDGSEEEDSNFTKS-VMGTEGYAAPEYISAGNLTTMSDVFSFGVVLLEMLTARKA 290 Query 1100 SSQSPPTKFLELIGIAQGQM-TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 + + L+ A+ + +L +++ + + L C Sbjct 291 VEKYRAQRGRNLVEWARPMLKDPNKLERIIDPSLEGKYSVEGIRKAAALAYQCLSHNPKS 350 Query 1159 RPTFENLIPILKTVHEKYQGQ 1179 RPT ++ L+ + + Q Sbjct 351 RPTMTTVVKTLEPILDLKDIQ 371 Score = 230 bits (586), Expect = 8e-65, Method: Composition-based stats. Identities = 70/343 (20%), Positives = 133/343 (39%), Gaps = 56/343 (16%) Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEGS 613 + SN I ++ +N+ ++ + + ++ + LG+G VY+G + Sbjct 49 SDFSNSTISLNDFSNSFFINIHIFTYEELKTITQGFSKYNFLGEGGFGEVYKGFVDDSLK 108 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 ++ V +K L + ++ Q+ H HL + Sbjct 109 TGL------------------KDQPVAVKALKREGGQGHREWLAEVIILGQLKHPHLVNL 150 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLE--NKNL 730 G C E ++V EY+E G L+ L ++ G +P ++ + A L +L K + Sbjct 151 VGYCCEDDERLLVYEYMERGNLEDHLFQKYGGALPWLTRVKILLGAAKGLEFLHKQEKPV 210 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECL 784 ++ + NILL+ + KLSD G+ E+ + + APE + Sbjct 211 IYRDFKPSNILLSSDFSS-------KLSDFGLATDGSEEEDSNFTKSVMGTEGYAAPEYI 263 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ------HRLPEPSC 838 G +L+T D + FG LLE+ +A + R+ + + ++L Sbjct 264 SAG--NLTTMSDVFSFGVVLLEMLTARKAVEKYRAQRGRNLVEWARPMLKDPNKLERIID 321 Query 839 PQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRL 869 P L A L QCL++ P RP+ T+++ L + Sbjct 322 PSLEGKYSVEGIRKAAALAYQCLSHNPKSRPTMTTVVKTLEPI 364 >sp|P97504|BMX_MOUSE Cytoplasmic tyrosine-protein kinase BMX OS=Mus musculus OX=10090 GN=Bmx PE=2 SV=1 Length=651 Score = 258 bits (660), Expect = 1e-72, Method: Composition-based stats. Identities = 97/351 (28%), Positives = 155/351 (44%), Gaps = 29/351 (8%) Query 829 RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA-- 886 + + + + +L + C P + + H ++ P S A Sbjct 323 KHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGMITRLRHPVSTKANKVPVSVALG 382 Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 S + + +++LG G FG V L + D VAVK +K G + Q Sbjct 383 SGIWELKREEITLLKELGNGQFGVVQLGQWKGQYD-----VAVKMIKE--GAMSEDEFFQ 435 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFA 1004 E + L H ++K+ G C + + +V EY+ G L +YL H GL QLL Sbjct 436 EAQTMMKLSHPKLVKFYGVCSKK--YPIYIVTEYITNGCLLNYLKSHGKGLESCQLLEMC 493 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 +CEGMA+L + +IHRDLAARN L+D+D VK+ DFG+ + V + + Y P Sbjct 494 YDVCEGMAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLD--DQYVSSVGTKFP 551 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 V W APE +K+ SDVW+FG+ ++E+ + L + Sbjct 552 VKWSAPEVFHYFKYSSKSDVWAFGILMWEVFS--------------LGKQPYDLYDNSEV 597 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 + +G RL RP +Y +M +CW RPTF+ L+ ++ + E+ Sbjct 598 VVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPLREQ 648 Score = 255 bits (652), Expect = 1e-71, Method: Composition-based stats. Identities = 83/436 (19%), Positives = 161/436 (37%), Gaps = 64/436 (15%) Query 449 DGIHGPLLEPFVQAKLRPE--DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFP 506 D G + + LR + +G +++ S+ + TV+ S+A + + ++ + Sbjct 271 DWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQMG---MYTVSLFSKAVNDKKGT-VKHYH 326 Query 507 IEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRG 566 + + F S+ +L Q + LR + Sbjct 327 VHTNAENKLYLAENYCFDSIPKLIHYHQHN---SAGMITRLRHP------------VSTK 371 Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 A P ++ L + ++EIT L LG G V G+ + Sbjct 372 ANKVPVSVALGS-GIWELKREEITLLKELGNGQFGVVQLGQWKG---------------- 414 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 + V +K++ F++ A M ++SH L +GVC + +V Sbjct 415 ---------QYDVAVKMIKEGAMS-EDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIV 464 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 TEY+ +G L +L+ + + + + +++LE+ +H ++ RN L+ Sbjct 465 TEYITNGCLLNYLKSHGKGLESCQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVD--- 521 Query 747 LAEGTSPFIKLSDPGVGLGALSREE--RVER---IPWLAPECLPGGANSLSTAMDKWGFG 801 + +K+SD G+ L + V + W APE S+ D W FG Sbjct 522 ----SDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFH--YFKYSSKSDVWAFG 575 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859 + E+ G+ P SE + HRL P+ + + + C P +RP+F Sbjct 576 ILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKRPTF 635 Query 860 RTILRDLTRLQPHNLA 875 + +L + L+ + Sbjct 636 QQLLSAIEPLREQDKP 651 >sp|Q07E01|MET_ORNAN Hepatocyte growth factor receptor OS=Ornithorhynchus anatinus OX=9258 GN=MET PE=3 SV=1 Length=1382 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 87/287 (30%), Positives = 136/287 (47%), Gaps = 19/287 (7%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 + +G GHFG V ND AVK+L + S + E I++ Sbjct 1078 MVHFTEIIGRGHFGCVYHGTLLD-NDDKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFS 1136 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAY 1013 H +++ G C + L +V+ Y+ G LR+++ H+ + L+ F Q+ +GM Y Sbjct 1137 HPNVLSLLGICLRREGSPL-VVLPYMKHGDLRNFIRNESHNPTVKDLIGFGLQVAKGMKY 1195 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPEC 1072 L ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E Sbjct 1196 LASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALES 1255 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 L+ KF SDVWSFGV L+EL+T + +T L +G Sbjct 1256 LQTQKFTSKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITVYLLQGR 1301 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 RL +P+ CP ++ +M CW A RP+F L+ + + + G+ Sbjct 1302 RLLQPEYCPDPLFEVMLKCWHPNAEMRPSFSELVSKIAVIFSTFIGE 1348 Score = 228 bits (581), Expect = 2e-59, Method: Composition-based stats. Identities = 68/401 (17%), Positives = 135/401 (34%), Gaps = 42/401 (10%) Query 507 IEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRG 566 + + + FP+ + G+ Q A P + + + Sbjct 997 VSNESVDYRATFPEDQFPNSSQNGSCRQAHYPLADLSPILSSGDSNPSSPLLQSNVHIDI 1056 Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 + +P + Q D + +G+G VY G L Sbjct 1057 SALNPDLVQAVQHVVIGPDSLMVHFTEIIGRGHFGCVYHGTLLDND-------------- 1102 Query 627 LVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENI 684 +++ +K L+ + + F +M SH ++ + G+C+R + Sbjct 1103 -------DKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNVLSLLGICLRREGSPL 1155 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 +V Y++HG L ++R E + + + Q+A + YL +K VH ++ RN +L Sbjct 1156 VVLPYMKHGDLRNFIRNESHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDE 1215 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVE--------RIPWLAPECLPGGANSLSTAMD 796 +K++D G+ +E + W+A E L ++ D Sbjct 1216 K-------FTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQT--QKFTSKSD 1266 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854 W FG L E+ G P + + + + RL PE L + +C Sbjct 1267 VWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLFEVMLKCWHPNAE 1326 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895 RPSF ++ + + + + + + V Sbjct 1327 MRPSFSELVSKIAVIFSTFIGEHYVHVNATYVNVKCVAPYP 1367 >sp|Q06806|TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mus musculus OX=10090 GN=Tie1 PE=1 SV=3 Length=1134 Score = 267 bits (682), Expect = 1e-72, Method: Composition-based stats. Identities = 105/351 (30%), Positives = 147/351 (42%), Gaps = 40/351 (11%) Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 CL T + + + L P V + +GE Sbjct 784 RSCLHRRRTFTYQSGSGEETILQFSSGTLTLTRRPKPQPEPLSYPVLEWEDITFEDLIGE 843 Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKG 964 G+FG+V DG A+K LK + E+++L L +H +II G Sbjct 844 GNFGQVIRAMIK--KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 901 Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFAQQI 1007 CE++G L + +EY P G+L D+L + ++ QLL FA Sbjct 902 ACENRG--YLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDA 959 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 GM YL + +IHRDLAARNVL+ + KI DFGL++ G E Y + G PV W Sbjct 960 ANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSR----GEEVYVKKTMGRLPVRW 1015 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 A E L + SDVWSFGV L+E+++ L G MT L E Sbjct 1016 MAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCGMTCAELYEK 1061 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 L +G R+ +P C EVY LM+ CW RP F + L + E + Sbjct 1062 LPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARKA 1112 Score = 239 bits (610), Expect = 2e-63, Method: Composition-based stats. Identities = 69/352 (20%), Positives = 130/352 (37%), Gaps = 58/352 (16%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 + L + R + P L+ L + ++IT +G+G V ++ +G Sbjct 809 SGTLTLTRRPKPQPEPLSYPVLEW-----EDITFEDLIGEGNFGQVIRAMIKKDGL---- 859 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQV-SHTHLAFVHG 675 ++ +K+L + + F ++ ++ H ++ + G Sbjct 860 ------------------KMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 901 Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLAS 720 C + EY +G L +LR+ R + + A A+ Sbjct 902 ACENRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAAN 961 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP-- 777 + YL K +H ++ RN+L+ G + K++D G+ G + ++ + R+P Sbjct 962 GMQYLSEKQFIHRDLAARNVLV-------GENLASKIADFGLSRGEEVYVKKTMGRLPVR 1014 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PE 835 W+A E L + +T D W FG L EI G P + +E + +R+ P Sbjct 1015 WMAIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPR 1072 Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 ++ L QC P +RP F I L R+ A V ++ Sbjct 1073 NCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARKAYVNMSLFENFTY 1124 >sp|Q9XI87|VIK_ARATH Serine/threonine-protein kinase VIK OS=Arabidopsis thaliana OX=3702 GN=VIK PE=1 SV=1 Length=438 Score = 252 bits (643), Expect = 1e-72, Method: Composition-based stats. Identities = 75/281 (27%), Positives = 125/281 (44%), Gaps = 32/281 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960 +G+G FG++ + G VAVK + ++ E+D+L L H +I+ Sbjct 168 IGKGSFGEIVKAYWR------GTPVAVKRILPSLSDDRLVIQDFRHEVDLLVKLRHPNIV 221 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQH- 1018 ++ G ++ K L L+ EY+ G L YL + + + FA I GM YLH + Sbjct 222 QFLGAVTER--KPLMLITEYLRGGDLHQYLKEKGGLTPTTAVNFALDIARGMTYLHNEPN 279 Query 1019 -YIHRDLAARNVLL--DNDRLVKIGDFGLAKAVPEGHEYYRVREDG-DSPVFWYAPECLK 1074 IHRDL RNVLL + +K+GDFGL+K + + + + G + APE K Sbjct 280 VIIHRDLKPRNVLLVNSSADHLKVGDFGLSKLIKVQNSHDVYKMTGETGSYRYMAPEVFK 339 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 ++ DV+SF + LYE+L + + G R Sbjct 340 HRRYDKKVDVFSFAMILYEMLEGEPPF---------------ANHEPYEAAKHVSDGHRP 384 Query 1135 P-RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 R C ++ L+ CW+ + + RP+F +++ L+ + E Sbjct 385 TFRSKGCTPDLRELIVKCWDADMNQRPSFLDILKRLEKIKE 425 Score = 219 bits (558), Expect = 4e-61, Method: Composition-based stats. Identities = 61/315 (19%), Positives = 115/315 (37%), Gaps = 53/315 (17%) Query 582 HRVDQKEITQLS--HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 ++ E+ + +G+G+ + + R V Sbjct 153 WEIEPAELDFSNAAMIGKGSFGEIVKAYWRG--------------------------TPV 186 Query 640 VLKVLDPSHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +K + PS D + F L+ ++ H ++ G +++TEY+ G L Sbjct 187 AVKRILPSLSDDRLVIQDFRHEVDLLVKLRHPNIVQFLGAVTERKPLMLITEYLRGGDLH 246 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPF 754 +L +E+G + + A +A ++YL N+ ++H ++ RN+LL ++ Sbjct 247 QYL-KEKGGLTPTTAVNFALDIARGMTYLHNEPNVIIHRDLKPRNVLL-----VNSSADH 300 Query 755 IKLSDPGVGL--------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 +K+ D G+ ++APE +D + F L E Sbjct 301 LKVGDFGLSKLIKVQNSHDVYKMTGETGSYRYMAPEVFKH--RRYDKKVDVFSFAMILYE 358 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEP---SCPQLATLTSQCLTYEPTQRPSFRTIL 863 + +GE P + P E HR P L L +C + QRPSF IL Sbjct 359 ML-EGEPPFANHEPYEAAKHVSDGHRPTFRSKGCTPDLRELIVKCWDADMNQRPSFLDIL 417 Query 864 RDLTRLQPHNLADVL 878 + L +++ +D Sbjct 418 KRLEKIKETLPSDHH 432 >sp|Q9LQQ8|PBL5_ARATH Probable serine/threonine-protein kinase PBL5 OS=Arabidopsis thaliana OX=3702 GN=PBL5 PE=2 SV=1 Length=423 Score = 251 bits (641), Expect = 2e-72, Method: Composition-based stats. Identities = 81/301 (27%), Positives = 135/301 (45%), Gaps = 19/301 (6%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 + LGEG FGKV + + ++VA+K L + G Q + E+ L Sbjct 102 NFRSDCFLGEGGFGKVFKGTIEKLD----QVVAIKQLDRN-GVQGIREFVVEVLTLSLAD 156 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEG 1010 H +++K G C + ++ LV EY+P GSL D+L + + + A G Sbjct 157 HPNLVKLIGFCAEGDQR--LLVYEYMPQGSLEDHLHVLPSGKKPLDWNTRMKIAAGAARG 214 Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH + I+RDL N+LL D K+ DFGLAK P G + + V + Sbjct 215 LEYLHDRMTPPVIYRDLKCSNILLGEDYQPKLSDFGLAKVGPSGDKTH-VSTRVMGTYGY 273 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLR-LT 1125 AP+ + + SD++SFGV L EL+T + + T K L+G A+ R Sbjct 274 CAPDYAMTGQLTFKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLFKDRRNFP 333 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV-HEKYQGQAPSVF 1184 ++++ + P + + + C + + + RP +++ L + KY +PS Sbjct 334 KMVDPLLQGQYPVRGLYQALAISAMCVQEQPTMRPVVSDVVLALNFLASSKYDPNSPSSS 393 Query 1185 S 1185 S Sbjct 394 S 394 Score = 222 bits (566), Expect = 3e-62, Method: Composition-based stats. Identities = 63/370 (17%), Positives = 119/370 (32%), Gaps = 66/370 (18%) Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 + +T +L+ LG+G V++G + Sbjct 82 QVTGKKAQTFTFQELA---EATGNFRSDCFLGEGGFGKVFKGTIEKLDQ----------- 127 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 V +K LD + F +S H +L + G C G + + Sbjct 128 -------------VVAIKQLDRNGVQGIREFVVEVLTLSLADHPNLVKLIGFCAEGDQRL 174 Query 685 MVTEYVEHGPLDVWLR---RERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGR 738 +V EY+ G L+ L + + +M +A A L YL ++ +++ ++ Sbjct 175 LVYEYMPQGSLEDHLHVLPSGKKPLDWNTRMKIAAGAARGLEYLHDRMTPPVIYRDLKCS 234 Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLS 792 NILL G KLSD G+ S ++ + + AP+ G L+ Sbjct 235 NILL-------GEDYQPKLSDFGLAKVGPSGDKTHVSTRVMGTYGYCAPDYAMTG--QLT 285 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ------RQHRLPEPSCPQL----- 841 D + FG LLE+ +A +++ ++ + P+ P L Sbjct 286 FKSDIYSFGVVLLELITGRKAIDNTKTRKDQNLVGWARPLFKDRRNFPKMVDPLLQGQYP 345 Query 842 -------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894 +++ C+ +PT RP ++ L L + Sbjct 346 VRGLYQALAISAMCVQEQPTMRPVVSDVVLALNFLASSKYDPNSPSSSSGKNPSFHRDRD 405 Query 895 RYLKKIRDLG 904 K+ + Sbjct 406 DEEKRPHLVK 415 >sp|F4HQ17|LRL14_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 1.4 OS=Arabidopsis thaliana OX=3702 GN=LRK10L-1.4 PE=2 SV=2 Length=663 Score = 258 bits (660), Expect = 2e-72, Method: Composition-based stats. Identities = 78/319 (24%), Positives = 139/319 (44%), Gaps = 22/319 (7%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH 940 + R+LG+G FG V G VAVK L + + Sbjct 318 YCGVQVFSYEELEEATENFSRELGDGGFGTVYYGVLK-----DGRAVAVKRL-YERSLKR 371 Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SI 995 +K EI+IL++L H +++ G C + + L LV EY+ G+L ++L + + Sbjct 372 VEQFKNEIEILKSLKHPNLVILYG-CTSRHSRELLLVYEYISNGTLAEHLHGNRAEARPL 430 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + L A + +++LH + IHRD+ N+LLD++ VK+ DFGL++ P + Sbjct 431 CWSTRLNIAIETASALSFLHIKGIIHRDIKTTNILLDDNYQVKVADFGLSRLFPMDQTHI 490 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGI 1114 G + PE + Y+ SDV+SFGV L EL++ ++ + + L + Sbjct 491 STAPQG--TPGYVDPEYYQCYQLNEKSDVYSFGVVLTELISSKEAVDITRHRHDINLANM 548 Query 1115 AQGQMTVLRLTELLERGERLPRPDKC---PCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 A ++ L EL++ + V L C + E RP + ++ IL+ Sbjct 549 AVSKIQNNALHELVDSSLGYDNDPEVRRKMMAVAELAFRCLQQERDVRPAMDEIVEILRG 608 Query 1172 VHEKYQG----QAPSVFSV 1186 + + + ++P V + Sbjct 609 IKDDEKKRVLVKSPDVVDI 627 Score = 210 bits (535), Expect = 4e-56, Method: Composition-based stats. Identities = 59/326 (18%), Positives = 109/326 (33%), Gaps = 63/326 (19%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 + S+ +++ LG G VY G L+ Sbjct 319 CGVQVFSYEELEEATENFSRELGDGGFGTVYYGVLKDGR--------------------- 357 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV-CVRGPENIMVTEYVEH 692 V +K L F ++ + H +L ++G E ++V EY+ + Sbjct 358 ----AVAVKRLYERSLKRVEQFKNEIEILKSLKHPNLVILYGCTSRHSRELLLVYEYISN 413 Query 693 GPLDVWLRRERG---HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 G L L R + + ++ +A + ASALS+L K ++H ++ NILL Sbjct 414 GTLAEHLHGNRAEARPLCWSTRLNIAIETASALSFLHIKGIIHRDIKTTNILLD------ 467 Query 750 GTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 + +K++D G+ + + ++ PE L+ D + FG L Sbjct 468 -DNYQVKVADFGLSRLFPMDQTHISTAPQGTPGYVDPEYYQ--CYQLNEKSDVYSFGVVL 524 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLP--------------------EPSCPQLATL 844 E+ EA +R + ++ +A L Sbjct 525 TELISSKEAVDITRHRHDINLANMAVSKIQNNALHELVDSSLGYDNDPEVRRKMMAVAEL 584 Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQ 870 +CL E RP+ I+ L ++ Sbjct 585 AFRCLQQERDVRPAMDEIVEILRGIK 610 >sp|Q86AT8|SPKA_DICDI Stress-activated protein kinase alpha OS=Dictyostelium discoideum OX=44689 GN=spkA-1 PE=1 SV=1 Length=638 Score = 257 bits (657), Expect = 2e-72, Method: Composition-based stats. Identities = 81/334 (24%), Positives = 145/334 (43%), Gaps = 20/334 (6%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 T +P + P P +++ + + + L+ LG G G Sbjct 305 TKKP-KTPELIIEEDPTPPDTPDISGLRHSLHTLRHVGEVNIINDNELEYTEKLGAGSSG 363 Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 KV Y G+ VA+K LK+ + +K+E I+ + +H++ + G Sbjct 364 KVYKGLYR------GKEVAIKVLKSMTESKEIEEFKKEFQIMSAIRSKHVVHFYGAVL-- 415 Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSI--GLAQLLLFAQQICEGMAYLHA--QHYIHRDLA 1025 E L +VME GSL + +S+ G + FA + G+ LH +HRDL Sbjct 416 -EPKLCMVMENCSRGSLYHVMDNNSLDIGWERTFRFAIETVRGIECLHKWDPPIVHRDLK 474 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 + N+L+++ +K+ DFGL++ + V+ G + APE +F SDV+ Sbjct 475 SLNLLVNDKWEIKVCDFGLSRFNTGSNLETLVKMRG--TFAYCAPEVYYGEQFSGKSDVY 532 Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 S V L+EL+T C + + F E + Q + + ++ R P+ CP + Sbjct 533 SIAVILWELVTRCINGRY-ERPFSEYKNL---QHDFQIIIQTAKKNLRPTIPNACPESLV 588 Query 1146 HLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L+++CW+ RPT +++ L T+ +Y+ Sbjct 589 SLIQDCWDPNLENRPTCTDILSRLVTIENEYRSN 622 Score = 182 bits (463), Expect = 6e-47, Method: Composition-based stats. Identities = 58/346 (17%), Positives = 108/346 (31%), Gaps = 60/346 (17%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 P P +T ++ +R + + R + + ++ E+ LG G+ VY+G R + Sbjct 319 PTPPDTPDISGLRHSLHTLRHVG----EVNIINDNELEYTEKLGAGSSGKVYKGLYRGK- 373 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLA 671 V +KVL + F + +MS + H+ Sbjct 374 -------------------------EVAIKVLKSMTESKEIEEFKKEFQIMSAIRSKHVV 408 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE--NKN 729 +G + P+ MV E G L + + A + + L + Sbjct 409 HFYGAVLE-PKLCMVMENCSRGSLYHVMDNNSLDIGWERTFRFAIETVRGIECLHKWDPP 467 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-----ERVERIPWLAPECL 784 +VH ++ N+L+ IK+ D G+ + + APE Sbjct 468 IVHRDLKSLNLLVNDK-------WEIKVCDFGLSRFNTGSNLETLVKMRGTFAYCAPEVY 520 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR------------QHR 832 G S D + L E+ R SE ++ + Sbjct 521 YG--EQFSGKSDVYSIAVILWELVTRCINGRYERPFSEYKNLQHDFQIIIQTAKKNLRPT 578 Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 +P L +L C RP+ IL L ++ +++ Sbjct 579 IPNACPESLVSLIQDCWDPNLENRPTCTDILSRLVTIENEYRSNIQ 624 >sp|Q9ZUF4|RIPK_ARATH Serine/threonine-protein kinase RIPK OS=Arabidopsis thaliana OX=3702 GN=RIPK PE=1 SV=1 Length=462 Score = 252 bits (643), Expect = 2e-72, Method: Composition-based stats. Identities = 83/283 (29%), Positives = 127/283 (45%), Gaps = 13/283 (5%) Query 901 RDLGEGHFGKVSLYCYDPTND--GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 LGEG FG V D + VAVK L + HR W E+ L L H++ Sbjct 91 NFLGEGGFGPVHKGFIDDKLRPGLKAQPVAVKLLDLEGLQGHRE-WLTEVMFLGQLKHKN 149 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLH 1015 ++K G C ++ ++ LV E++P GSL + L R S+ + + A G+ +LH Sbjct 150 LVKLIGYCCEEEHRT--LVYEFMPRGSLENQLFRRYSASLPWSTRMKIAHGAATGLQFLH 207 Query 1016 A--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 I+RD A N+LLD+D K+ DFGLAK PEG + + V + APE + Sbjct 208 EAENPVIYRDFKASNILLDSDYTAKLSDFGLAKDGPEGDDTH-VSTRVMGTQGYAAPEYI 266 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTELLERG 1131 SDV+SFGV L ELLT S + ++ L+ A+ + R L+ +++ Sbjct 267 MTGHLTARSDVYSFGVVLLELLTGRRSVDKKRSSREQNLVDWARPMLNDPRKLSRIMDPR 326 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + + L C RP ++ IL + + Sbjct 327 LEGQYSETGARKAATLAYQCLSHRPKNRPCMSAVVSILNDLKD 369 Score = 234 bits (598), Expect = 3e-66, Method: Composition-based stats. Identities = 73/346 (21%), Positives = 131/346 (38%), Gaps = 54/346 (16%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 L++ L+ +V + + + LG+G V++G + +D L PG Sbjct 70 SDLHVFTLAELKVITQSFSSTNFLGEGGFGPVHKGFI---------------DDKLRPGL 114 Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 + V +K+LD + + Q+ H +L + G C +V E++ Sbjct 115 ---KAQPVAVKLLDLEGLQGHREWLTEVMFLGQLKHKNLVKLIGYCCEEEHRTLVYEFMP 171 Query 692 HGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLA 748 G L+ L R +P + +M +A A+ L +L +++ + NILL Sbjct 172 RGSLENQLFRRYSASLPWSTRMKIAHGAATGLQFLHEAENPVIYRDFKASNILLD----- 226 Query 749 EGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGA 802 + KLSD G+ ++ + + APE + G L+ D + FG Sbjct 227 --SDYTAKLSDFGLAKDGPEGDDTHVSTRVMGTQGYAAPEYIMTG--HLTARSDVYSFGV 282 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQ------HRLPEPSCPQL------------ATL 844 LLE+ + + RS E+ + +L P+L ATL Sbjct 283 VLLELLTGRRSVDKKRSSREQNLVDWARPMLNDPRKLSRIMDPRLEGQYSETGARKAATL 342 Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 QCL++ P RP ++ L L+ +N + T P + Sbjct 343 AYQCLSHRPKNRPCMSAVVSILNDLKDYNDIPMGTFTYTVPNTPDN 388 >sp|Q03351|NTRK3_RAT NT-3 growth factor receptor OS=Rattus norvegicus OX=10116 GN=Ntrk3 PE=1 SV=2 Length=864 Score = 262 bits (670), Expect = 3e-72, Method: Composition-based stats. Identities = 114/373 (31%), Positives = 162/373 (43%), Gaps = 73/373 (20%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY- 914 P I + + N P + +R + R+LGEG FGKV L Sbjct 497 GPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAE 556 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 CY+ + +VAVKALK D R +++E ++L L HEHI+K+ G C D L Sbjct 557 CYNLSPTKDKMLVAVKALK-DPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGD--PL 613 Query 975 QLVMEYVPLGSLRDYLPRHS-----------------IGLAQLLLFAQQICEGMAYLHAQ 1017 +V EY+ G L +L H +GL+Q+L A QI GM YL +Q Sbjct 614 IMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQ 673 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAV----------------------------- 1048 H++HRDLA RN L+ + LVKIGDFG+++ V Sbjct 674 HFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYREGPYQKGPFSVSWQQQRLAASA 733 Query 1049 ------PEGHEYYRVREDGD---SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 P G+++ E G P+ W PE + KF SDVWSFGV L+E+ T+ Sbjct 734 ASTLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGK 793 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 Q++ + E + +G L RP CP EVY +M CW+ E R Sbjct 794 Q--------------PWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQR 839 Query 1160 PTFENLIPILKTV 1172 + + IL + Sbjct 840 LNIKEIYKILHAL 852 Score = 249 bits (636), Expect = 9e-68, Method: Composition-based stats. Identities = 73/348 (21%), Positives = 126/348 (36%), Gaps = 90/348 (26%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + +++I LG+G V+ + + L P +D+ + V +K Sbjct 533 IKRRDIVLKRELGEGAFGKVF----------------LAECYNLSPTKDK---MLVAVKA 573 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702 L F A L++ + H H+ +GVC G IMV EY++HG L+ +LR Sbjct 574 LKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHG 633 Query 703 --------------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 +G + ++ + +A Q+AS + YL +++ VH ++ RN L+ Sbjct 634 PDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV------ 687 Query 749 EGTSPFIKLSDPGVGLGALSREE------------------------------------- 771 G + +K+ D G+ S + Sbjct 688 -GANLLVKIGDFGMSRDVYSTDYYREGPYQKGPFSVSWQQQRLAASAASTLFNPSGNDFC 746 Query 772 --------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + I W+ PE + +T D W FG L EI G+ P S +E Sbjct 747 IWCEVGGHTMLPIRWMPPESIM--YRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEV 804 Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + L P ++ + C EP QR + + I + L L Sbjct 805 IECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHAL 852 >sp|P23049|SEA_AVIET Tyrosine-protein kinase transforming protein SEA OS=Avian erythroblastosis virus (strain S13) OX=11863 GN=V-SEA PE=3 SV=2 Length=370 Score = 248 bits (634), Expect = 3e-72, Method: Composition-based stats. Identities = 95/286 (33%), Positives = 140/286 (49%), Gaps = 21/286 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 + R +G GHFG V Y G AVK+L + + +E +++ +H Sbjct 61 HRSRVIGRGHFGSVYHGTYMDPLLG-NLHCAVKSLHRITYLEEVEEFLREGILMKGFHHP 119 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLH 1015 ++ G C + L +V+ Y+ G LR ++ S + +L+ F Q+ GM YL Sbjct 120 QVLSLLGVCLPRHGLPL-VVLPYMRHGDLRHFVRAQERSPTVKELIGFGLQVALGMEYLA 178 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE--DGDSPVFWYAPECL 1073 + ++HRDLAARN +LD VK+ DFGLA+ V G EYY +R+ PV W A E L Sbjct 179 QKKFVHRDLAARNCMLDETLTVKVADFGLARDVF-GKEYYSIRQHRHAKLPVRWMALESL 237 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + KF SDVWSFGV ++ELLT S ++ + L RG R Sbjct 238 QTQKFTTKSDVWSFGVLMWELLTRGAS--------------PYPEVDPYDMARYLLRGRR 283 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 LP+P CP +Y +M +CW RP+F L+ L+ V +G+ Sbjct 284 LPQPQPCPDTLYGVMLSCWAPTPEERPSFSGLVCELERVLASLEGE 329 Score = 213 bits (543), Expect = 7e-60, Method: Composition-based stats. Identities = 65/315 (21%), Positives = 115/315 (37%), Gaps = 44/315 (14%) Query 564 MRGARASPRTLNLSQLSFHRVDQKEIT--QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 R L ++ + ++ + + +G+G +VY G G+ Sbjct 33 TSCCLEDLRPELLEEVKDILIPEERLITHRSRVIGRGHFGSVYHGTYMDPLLGNLHC--- 89 Query 622 DDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCV-R 679 +K L ++ + F LM H + + GVC+ R Sbjct 90 ------------------AVKSLHRITYLEEVEEFLREGILMKGFHHPQVLSLLGVCLPR 131 Query 680 GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRN 739 ++V Y+ HG L ++R + + + Q+A + YL K VH ++ RN Sbjct 132 HGLPLVVLPYMRHGDLRHFVRAQERSPTVKELIGFGLQVALGMEYLAQKKFVHRDLAARN 191 Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER--------IPWLAPECLPGGANSL 791 +L + +K++D G+ +E R + W+A E L Sbjct 192 CMLDE-------TLTVKVADFGLARDVFGKEYYSIRQHRHAKLPVRWMALESLQT--QKF 242 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCPQ-LATLTSQCL 849 +T D W FG + E+ G +P P + + R RLP+ CP L + C Sbjct 243 TTKSDVWSFGVLMWELLTRGASPYPEVDPYDMARYLLRGRRLPQPQPCPDTLYGVMLSCW 302 Query 850 TYEPTQRPSFRTILR 864 P +RPSF ++ Sbjct 303 APTPEERPSFSGLVC 317 >sp|Q16832|DDR2_HUMAN Discoidin domain-containing receptor 2 OS=Homo sapiens OX=9606 GN=DDR2 PE=1 SV=2 Length=855 Score = 262 bits (669), Expect = 3e-72, Method: Composition-based stats. Identities = 94/293 (32%), Positives = 142/293 (48%), Gaps = 36/293 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGE------------MVAVKALKADCGPQHRSGWKQEID 949 LGEG FG+V L + + +VAVK L+AD R+ + +EI Sbjct 568 KLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIK 627 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------SIGLA 998 I+ L +II C + L ++ EY+ G L +L RH ++ Sbjct 628 IMSRLKDPNIIHLLAVCI--TDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYT 685 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 L A QI GM YL + +++HRDLA RN L+ + +KI DFG+++ + G +YYR++ Sbjct 686 NLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSG-DYYRIQ 744 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 P+ W + E + KF ASDVW+FGVTL+E T C Q P L + + Sbjct 745 GRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFC---QEQPYSQLSDEQVIENT 801 Query 1119 MTVLRLTELLERGER--LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 R ++G + LP+P CP VY LM +CW + RP+F+ + +L Sbjct 802 GEFFR-----DQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849 Score = 234 bits (597), Expect = 9e-63, Method: Composition-based stats. Identities = 75/316 (24%), Positives = 124/316 (39%), Gaps = 43/316 (14%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L+ ++ +K +T LG+G V+ + E + + Sbjct 548 LSGKDVAVEEFPRKLLTFKEKLGEGQFGEVH--------LCEVEGMEKFKDKDFALDVSA 599 Query 634 GQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 Q + V +K+L + A F + +MS++ ++ + VC+ M+TEY+E+ Sbjct 600 NQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMEN 659 Query 693 GPLDVWLRRERGH---------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 G L+ +L R V +A Q+AS + YL + N VH ++ RN L+ Sbjct 660 GDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLV- 718 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDK 797 G + IK++D G+ S + V I W++ E + G +TA D Sbjct 719 ------GKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLG--KFTTASDV 770 Query 798 WGFGATLLEIC-FDGEAPLQSRSPSEKE----HFYQRQHR-----LPEPSCPQLATLTSQ 847 W FG TL E F E P S + F++ Q R P + L Sbjct 771 WAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLS 830 Query 848 CLTYEPTQRPSFRTIL 863 C + RPSF+ I Sbjct 831 CWRRDTKNRPSFQEIH 846 >sp|Q26614|FGFR_STRPU Fibroblast growth factor receptor OS=Strongylocentrotus purpuratus OX=7668 GN=FGFR PE=2 SV=1 Length=972 Score = 264 bits (674), Expect = 4e-72, Method: Composition-based stats. Identities = 102/337 (30%), Positives = 153/337 (45%), Gaps = 35/337 (10%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 T S ++I + + D P F + L + +GEG FGKV + Sbjct 596 TSVDSTQSIAPLFGGRNRLTSSLTVISEYDIPLDPEWEFPRDRLTVGKTIGEGAFGKVVI 655 Query 914 YCYDP-TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGE 971 VAVK LKA+ + S E+ +++ + + +II GCC +G Sbjct 656 GEAVGIVCQEKTSTVAVKMLKANAMDREFSDLISELAMMKMIGKNPNIINLLGCCTQEGP 715 Query 972 KSLQLVMEYVPLGSLRDYLPRHSIGLA----------------QLLLFAQQICEGMAYLH 1015 +++E+ G+LRD+L L+ A Q+ GM +L Sbjct 716 P--YVIVEFAHHGNLRDFLRSRRPPEEYEKSILLTTSQTLTNKDLMSMAYQVARGMDFLA 773 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 ++ IHRDLAARNVL+ D +KI DFGLA+ + ++YR DG PV W APE L + Sbjct 774 SKKCIHRDLAARNVLVTEDFEMKICDFGLARDIHY-IDFYRKTTDGRLPVKWMAPEALFD 832 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 F SDVWSFG+ L+E++T L G + V ++ + L G+RL Sbjct 833 RMFTTQSDVWSFGILLWEIMT--------------LGGTPYPSVPVEQMFDYLRSGKRLE 878 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +P E+YH++ CW T RPTF L+ L + Sbjct 879 KPQNTSLEIYHILCECWRTSPGQRPTFCELVEDLDRI 915 Score = 222 bits (566), Expect = 2e-58, Method: Composition-based stats. Identities = 66/347 (19%), Positives = 121/347 (35%), Gaps = 52/347 (15%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + +T +G+G V + E G + K V + Sbjct 632 WEFPRDRLTVGKTIGEGAFGKV----VIGEAVGIVCQEKTS---------------TVAV 672 Query 642 KVLDPSHHDIAL-AFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 K+L + D ++M + + ++ + G C + ++ E+ HG L +L Sbjct 673 KMLKANAMDREFSDLISELAMMKMIGKNPNIINLLGCCTQEGPPYVIVEFAHHGNLRDFL 732 Query 700 RRERGH--------------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 R R + M +A Q+A + +L +K +H ++ RN+L+ Sbjct 733 RSRRPPEEYEKSILLTTSQTLTNKDLMSMAYQVARGMDFLASKKCIHRDLAARNVLVTE- 791 Query 746 GLAEGTSPFIKLSDPGVGLGAL----SREERVERIP--WLAPECLPGGANSLSTAMDKWG 799 +K+ D G+ R+ R+P W+APE L +T D W Sbjct 792 ------DFEMKICDFGLARDIHYIDFYRKTTDGRLPVKWMAPEALFDRM--FTTQSDVWS 843 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857 FG L EI G P S + + + RL P+ + ++ + +C P QRP Sbjct 844 FGILLWEIMTLGGTPYPSVPVEQMFDYLRSGKRLEKPQNTSLEIYHILCECWRTSPGQRP 903 Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 +F ++ DL R+ + + F + Sbjct 904 TFCELVEDLDRIISVSSNQDYLDLEAVGDAPVKTFQESERMAFMGFR 950 >sp|Q00944|FAK1_CHICK Focal adhesion kinase 1 OS=Gallus gallus OX=9031 GN=PTK2 PE=1 SV=2 Length=1053 Score = 265 bits (677), Expect = 4e-72, Method: Composition-based stats. Identities = 98/294 (33%), Positives = 141/294 (48%), Gaps = 24/294 (8%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQH 940 P++ + ++ R +GEG FG V Y P N VA+K K Sbjct 407 YTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPA--MAVAIKTCKNCTSDSV 464 Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLA 998 R + QE +R H HI+K G E + ++ME LG LR +L + S+ LA Sbjct 465 REKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIMELCTLGELRSFLQVRKFSLDLA 521 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 L+L+A Q+ +AYL ++ ++HRD+AARNVL+ VK+GDFGL++ + + Y Sbjct 522 SLILYAYQLSTALAYLESKRFVHRDIAARNVLVSATDCVKLGDFGLSRYMEDS--TYYKA 579 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 G P+ W APE + +F ASDVW FGV ++E+L H Sbjct 580 SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQ--------------G 625 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + + +E GERLP P CP +Y LM CW + S RP F L L T+ Sbjct 626 VKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTI 679 Score = 239 bits (609), Expect = 2e-63, Method: Composition-based stats. Identities = 68/305 (22%), Positives = 123/305 (40%), Gaps = 39/305 (13%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 T + + + ++ I +G+G +V++G + Sbjct 406 TYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQG---------------------IYMSP 444 Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 + V +K D F + A M Q H H+ + GV P ++ E Sbjct 445 ENPAMAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIMELCT 503 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G L +L+ + + +A ++ A QL++AL+YLE+K VH ++ RN+L++ Sbjct 504 LGELRSFLQVRKFSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVS-------A 556 Query 752 SPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 + +KL D G+ I W+APE + ++A D W FG + E Sbjct 557 TDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVCMWE 614 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 I G P Q ++ + R +P P L +L ++C Y+P++RP F + Sbjct 615 ILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKA 674 Query 865 DLTRL 869 L+ + Sbjct 675 QLSTI 679 >sp|O81906|B120_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase B120 OS=Arabidopsis thaliana OX=3702 GN=B120 PE=2 SV=1 Length=849 Score = 261 bits (668), Expect = 4e-72, Method: Composition-based stats. Identities = 83/284 (29%), Positives = 127/284 (45%), Gaps = 16/284 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 K +LG G FG V + G +AVK L G Q +K EI ++ L Sbjct 527 NDFCKENELGRGGFGPVYKGVLE-----DGREIAVKRLSGKSG-QGVDEFKNEIILIAKL 580 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEG 1010 H ++++ GCC + EK LV EY+P SL +L + I + I G Sbjct 581 QHRNLVRLLGCCFEGEEK--MLVYEYMPNKSLDFFLFDETKQALIDWKLRFSIIEGIARG 638 Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH IHRDL NVLLD + KI DFG+A+ G++ + Sbjct 639 LLYLHRDSRLRIIHRDLKVSNVLLDAEMNPKISDFGMARIFG-GNQNEANTVRVVGTYGY 697 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 +PE E F SDV+SFGV L E+++ ++ ++ LIG A T R EL Sbjct 698 MSPEYAMEGLFSVKSDVYSFGVLLLEIVSGKRNTSLRSSEHGSLIGYAWYLYTHGRSEEL 757 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 ++ R+ + H+ C + A+ RP +++ +L++ Sbjct 758 VDPKIRVTCSKREALRCIHVAMLCVQDSAAERPNMASVLLMLES 801 Score = 232 bits (592), Expect = 3e-62, Method: Composition-based stats. Identities = 54/262 (21%), Positives = 95/262 (36%), Gaps = 45/262 (17%) Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 I++ G + L + L+ + + + + LG+G VY+G L Sbjct 502 IMIEGKAVNTSELPVFSLNAIAIATNDFCKENELGRGGFGPVYKGVLEDGR--------- 552 Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 + +K L F L++++ H +L + G C G Sbjct 553 ----------------EIAVKRLSGKSGQGVDEFKNEIILIAKLQHRNLVRLLGCCFEGE 596 Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENK---NLVHGNVC 736 E ++V EY+ + LD +L E + WK+ + + +A L YL ++H ++ Sbjct 597 EKMLVYEYMPNKSLDFFLFDETKQALIDWKLRFSIIEGIARGLLYLHRDSRLRIIHRDLK 656 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANS 790 N+LL K+SD G+ + V +++PE G Sbjct 657 VSNVLLD-------AEMNPKISDFGMARIFGGNQNEANTVRVVGTYGYMSPEYAMEGL-- 707 Query 791 LSTAMDKWGFGATLLEICFDGE 812 S D + FG LLEI Sbjct 708 FSVKSDVYSFGVLLLEIVSGKR 729 >sp|Q8H1E3|PBL17_ARATH Probable serine/threonine-protein kinase PBL17 OS=Arabidopsis thaliana OX=3702 GN=PBL17 PE=1 SV=1 Length=442 Score = 250 bits (639), Expect = 5e-72, Method: Composition-based stats. Identities = 81/315 (26%), Positives = 134/315 (43%), Gaps = 13/315 (4%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG--TGEMVAVKA 931 ++ N D + + + LGEG FG V D + VA+K Sbjct 67 QSNPGYENVDIFTYEEMKIATKQFRPDYILGEGGFGVVYKGVIDESVRVGFKSTKVAIKE 126 Query 932 LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP 991 L + G Q W E++ L L H +++K G C + + LV EY+ +GSL +L Sbjct 127 LNPE-GFQGDREWLAEVNYLGQLSHPNLVKLIGYCCEDDHR--LLVYEYMAMGSLEKHLF 183 Query 992 RH---SIGLAQLLLFAQQICEGMAYLH--AQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 R ++ + + A +G+A+LH + I+RDL N+LLD K+ DFGLAK Sbjct 184 RRVGCTLTWTKRMKIALDAAKGLAFLHGAERSIIYRDLKTANILLDEGYNAKLSDFGLAK 243 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPP 1105 P G + + V + APE + SDV+ FGV L E+L + +S Sbjct 244 DGPRGDQTH-VSTRVMGTYGYAAPEYVMTGHLTSRSDVYGFGVLLLEMLLGKRAMDKSRA 302 Query 1106 TKFLELIGIAQGQMT-VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + L+ A+ + +L +++ K +V L C RP + Sbjct 303 CREHNLVEWARPLLNHNKKLLRIIDPRMDGQYGTKALMKVAGLAYQCLSQNPKGRPLMNH 362 Query 1165 LIPILKTVHEKYQGQ 1179 ++ +L+T+ + Q Sbjct 363 VVEVLETLKDDGDAQ 377 Score = 237 bits (605), Expect = 2e-67, Method: Composition-based stats. Identities = 70/350 (20%), Positives = 129/350 (37%), Gaps = 56/350 (16%) Query 564 MRGARASPRTLNLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 ++ +++P N+ ++ + K+ LG+G VY+G + Sbjct 63 IKDLQSNPGYENVDIFTYEEMKIATKQFRPDYILGEGGFGVVYKGVI------------- 109 Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 R + +V +K L+P + + + Q+SH +L + G C Sbjct 110 -----DESVRVGFKSTKVAIKELNPEGFQGDREWLAEVNYLGQLSHPNLVKLIGYCCEDD 164 Query 682 ENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGR 738 ++V EY+ G L+ L R G + +M +A A L++L +++++ ++ Sbjct 165 HRLLVYEYMAMGSLEKHLFRRVGCTLTWTKRMKIALDAAKGLAFLHGAERSIIYRDLKTA 224 Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLS 792 NILL KLSD G+ ++ + + APE + G L+ Sbjct 225 NILLDE-------GYNAKLSDFGLAKDGPRGDQTHVSTRVMGTYGYAAPEYVMTG--HLT 275 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS--------------- 837 + D +GFG LLE+ A +SR+ E + L Sbjct 276 SRSDVYGFGVLLLEMLLGKRAMDKSRACREHNLVEWARPLLNHNKKLLRIIDPRMDGQYG 335 Query 838 ---CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884 ++A L QCL+ P RP ++ L L+ A + Sbjct 336 TKALMKVAGLAYQCLSQNPKGRPLMNHVVEVLETLKDDGDAQEEVMTNLH 385 >sp|P35590|TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 OS=Homo sapiens OX=9606 GN=TIE1 PE=1 SV=1 Length=1138 Score = 265 bits (678), Expect = 5e-72, Method: Composition-based stats. Identities = 103/351 (29%), Positives = 146/351 (42%), Gaps = 40/351 (11%) Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 CL T + + + L V + +GE Sbjct 788 RSCLHRRRTFTYQSGSGEETILQFSSGTLTLTRRPKLQPEPLSYPVLEWEDITFEDLIGE 847 Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKG 964 G+FG+V DG A+K LK + E+++L L +H +II G Sbjct 848 GNFGQVIRAMIK--KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 905 Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFAQQI 1007 C+++G L + +EY P G+L D+L + ++ QLL FA Sbjct 906 ACKNRG--YLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDA 963 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 GM YL + +IHRDLAARNVL+ + KI DFGL++ G E Y + G PV W Sbjct 964 ANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSR----GEEVYVKKTMGRLPVRW 1019 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 A E L + SDVWSFGV L+E+++ L G MT L E Sbjct 1020 MAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCGMTCAELYEK 1065 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 L +G R+ +P C EVY LM+ CW RP F + L + E + Sbjct 1066 LPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARKA 1116 Score = 238 bits (607), Expect = 5e-63, Method: Composition-based stats. Identities = 69/352 (20%), Positives = 130/352 (37%), Gaps = 58/352 (16%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 + L + R + P L+ L + ++IT +G+G V ++ +G Sbjct 813 SGTLTLTRRPKLQPEPLSYPVLEW-----EDITFEDLIGEGNFGQVIRAMIKKDGL---- 863 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQV-SHTHLAFVHG 675 ++ +K+L + + F ++ ++ H ++ + G Sbjct 864 ------------------KMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 905 Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLAS 720 C + EY +G L +LR+ R + + A A+ Sbjct 906 ACKNRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAAN 965 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP-- 777 + YL K +H ++ RN+L+ G + K++D G+ G + ++ + R+P Sbjct 966 GMQYLSEKQFIHRDLAARNVLV-------GENLASKIADFGLSRGEEVYVKKTMGRLPVR 1018 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PE 835 W+A E L + +T D W FG L EI G P + +E + +R+ P Sbjct 1019 WMAIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPR 1076 Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 ++ L QC P +RP F I L R+ A V ++ Sbjct 1077 NCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARKAYVNMSLFENFTY 1128 >sp|Q95YD4|KIN32_CAEEL Inactive tyrosine-protein kinase kin-32 OS=Caenorhabditis elegans OX=6239 GN=kin-32 PE=1 SV=1 Length=867 Score = 261 bits (668), Expect = 5e-72, Method: Composition-based stats. Identities = 94/282 (33%), Positives = 140/282 (50%), Gaps = 22/282 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V Y VAVK K D P QE ++R H +II+ Sbjct 373 IGGGQFGNVYKAVYHDLEKDERIAVAVKVCKTDAEPADTQLILQESSLMRNFRHSNIIQL 432 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C DQ + LV+E P G LR+YL + + L L LF QIC+ + YLH+ ++ Sbjct 433 IGVCVDQ---PMWLVLELAPKGELREYLQQEKDWLPLRILTLFCSQICDSLVYLHSTRFV 489 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+AARN+L+ + + VK+ DFGL++A+ Y R G P+ W APE + +F Sbjct 490 HRDIAARNILVCSPQCVKLADFGLSRALDYDAVYTASR--GKLPIKWLAPESVNYRQFSM 547 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ASDVW FGV ++E+ + L +T + +E+G R P P+KC Sbjct 548 ASDVWMFGVCMWEIFS--------------LGVKPWAGVTNSDVIMHIEQGSRPPCPEKC 593 Query 1141 PCEVYHLMK-NCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 P +Y+ ++ W E RPT + + I++ V ++ P Sbjct 594 PTALYNFIRSKMWAIEPHKRPTVDQIYAIIEDVRQQIIQNIP 635 Score = 214 bits (544), Expect = 4e-56, Method: Composition-based stats. Identities = 80/367 (22%), Positives = 136/367 (37%), Gaps = 47/367 (13%) Query 524 PSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHR 583 S+ L Q + F L+ E + M A P+T N + S R Sbjct 310 QSLAHLLDGYQMLYNQRDSV-FKLKGI------ERCETLTMHEATIRPKTPN-NIDSNIR 361 Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + ++ IT +G G NVY+ + ++ + + V +KV Sbjct 362 LRRELITLKELIGGGQFGNVYKA--------------------VYHDLEKDERIAVAVKV 401 Query 644 LDPSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 + +SLM H+++ + GVCV P +V E G L +L++E Sbjct 402 CKTDAEPADTQLILQESSLMRNFRHSNIIQLIGVCVDQP-MWLVLELAPKGELREYLQQE 460 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + +P+ + Q+ +L YL + VH ++ RNIL+ + +KL+D G+ Sbjct 461 KDWLPLRILTLFCSQICDSLVYLHSTRFVHRDIAARNILV-------CSPQCVKLADFGL 513 Query 763 GLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 I WLAPE + S A D W FG + EI G P Sbjct 514 SRALDYDAVYTASRGKLPIKWLAPESV--NYRQFSMASDVWMFGVCMWEIFSLGVKPWAG 571 Query 818 RSPSEKEHFYQRQHRLPEP--SCPQLATLT-SQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 + S+ ++ R P P L S+ EP +RP+ I + ++ + Sbjct 572 VTNSDVIMHIEQGSRPPCPEKCPTALYNFIRSKMWAIEPHKRPTVDQIYAIIEDVRQQII 631 Query 875 ADVLTVN 881 ++ Sbjct 632 QNIPPEQ 638 >sp|O65479|CRK20_ARATH Putative cysteine-rich receptor-like protein kinase 20 OS=Arabidopsis thaliana OX=3702 GN=CRK20 PE=2 SV=2 Length=666 Score = 257 bits (656), Expect = 7e-72, Method: Composition-based stats. Identities = 78/282 (28%), Positives = 122/282 (43%), Gaps = 18/282 (6%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 I LG+G FG+V + +G VAVK L + G Q ++ E+ ++ L H + Sbjct 346 PINKLGQGGFGEVYKGTF-----PSGVQVAVKRLSKNSG-QGEKEFENEVVVVAKLQHRN 399 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYL 1014 ++K G C + EK LV E+VP SL +L + + ++ I G+ YL Sbjct 400 LVKLLGYCLEGEEK--ILVYEFVPNKSLDYFLFDPTMQGQLDWSRRYKIIGGIARGILYL 457 Query 1015 HAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 H IHRDL A N+LLD D K+ DFG+A+ R + APE Sbjct 458 HQDSRLTIIHRDLKAGNILLDADMNPKVADFGMARIFGMDQTEANTRR-VVGTYGYMAPE 516 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLTELLE 1129 KF SDV+SFGV + E+++ +S L+ + +EL++ Sbjct 517 YAMYGKFSMKSDVYSFGVLVLEIVSGMKNSSLDQMDGSISNLVTYTWRLWSNGSPSELVD 576 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 H+ C + +A+ RPT ++ +L T Sbjct 577 PSFGDNYQTSEITRCIHIALLCVQEDANDRPTMSAIVQMLTT 618 Score = 233 bits (593), Expect = 1e-63, Method: Composition-based stats. Identities = 58/324 (18%), Positives = 108/324 (33%), Gaps = 65/324 (20%) Query 573 TLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 T Q F + ++ LGQG VY+G Sbjct 326 TAGSLQFDFKAIVAATDIFLPINKLGQGGFGEVYKGT----------------------- 362 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 ++V +K L + F +++++ H +L + G C+ G E I+V E+V Sbjct 363 --FPSGVQVAVKRLSKNSGQGEKEFENEVVVVAKLQHRNLVKLLGYCLEGEEKILVYEFV 420 Query 691 EHGPLDVWLRRE--RGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745 + LD +L +G + + + + +A + YL + ++H ++ NILL Sbjct 421 PNKSLDYFLFDPTMQGQLDWSRRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNILLD-- 478 Query 746 GLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 K++D G+ + V ++APE G S D + Sbjct 479 -----ADMNPKVADFGMARIFGMDQTEANTRRVVGTYGYMAPEYAMYG--KFSMKSDVYS 531 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------------QL 841 FG +LEI + + + RL P + Sbjct 532 FGVLVLEIVSGMKNSSLDQMDGSISNLVTYTWRLWSNGSPSELVDPSFGDNYQTSEITRC 591 Query 842 ATLTSQCLTYEPTQRPSFRTILRD 865 + C+ + RP+ I++ Sbjct 592 IHIALLCVQEDANDRPTMSAIVQM 615 >sp|Q06805|TIE1_BOVIN Tyrosine-protein kinase receptor Tie-1 OS=Bos taurus OX=9913 GN=TIE1 PE=2 SV=1 Length=1136 Score = 265 bits (677), Expect = 7e-72, Method: Composition-based stats. Identities = 104/351 (30%), Positives = 147/351 (42%), Gaps = 40/351 (11%) Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 CL T + + + L P + V + +GE Sbjct 786 KSCLHRRRTFTYQSGSGEETILQFSSGTLTLTRRPKPQPEPLNYPVLEWEDITFEDLIGE 845 Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKG 964 G+FG+V DG A+K LK + E+++L L +H +II G Sbjct 846 GNFGQVIRAMIK--KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 903 Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFAQQI 1007 CE++G L + +EY P G+L D+L + ++ QLL FA Sbjct 904 ACENRG--YLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDA 961 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 GM YL + +IHRDLAARNVL+ + KI DFGL++ G E Y + G PV W Sbjct 962 ANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSR----GEEVYVKKTMGRLPVRW 1017 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 A E L + SDVWSFGV L+E+++ L G MT L E Sbjct 1018 MAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCGMTCAELYEK 1063 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 L + R+ +P C EVY LM+ CW RP F + L + E + Sbjct 1064 LPQAYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARKA 1114 Score = 239 bits (610), Expect = 2e-63, Method: Composition-based stats. Identities = 70/352 (20%), Positives = 130/352 (37%), Gaps = 58/352 (16%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 + L + R + P LN L + ++IT +G+G V ++ +G Sbjct 811 SGTLTLTRRPKPQPEPLNYPVLEW-----EDITFEDLIGEGNFGQVIRAMIKKDGL---- 861 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQV-SHTHLAFVHG 675 ++ +K+L + + F ++ ++ H ++ + G Sbjct 862 ------------------KMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 903 Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQLAS 720 C + EY +G L +LR+ R + + A A+ Sbjct 904 ACENRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAAN 963 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIP-- 777 + YL K +H ++ RN+L+ G + K++D G+ G + ++ + R+P Sbjct 964 GMQYLSEKQFIHRDLAARNVLV-------GENLASKIADFGLSRGEEVYVKKTMGRLPVR 1016 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PE 835 W+A E L + +T D W FG L EI G P + +E + +R+ P Sbjct 1017 WMAIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQAYRMEQPR 1074 Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 ++ L QC P +RP F I L R+ A V ++ Sbjct 1075 NCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARKAYVNMSLFENFTY 1126 >sp|Q9SYA0|Y1150_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61500 OS=Arabidopsis thaliana OX=3702 GN=At1g61500 PE=2 SV=2 Length=804 Score = 260 bits (664), Expect = 7e-72, Method: Composition-based stats. Identities = 85/350 (24%), Positives = 134/350 (38%), Gaps = 17/350 (5%) Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 L T R I ++L D Sbjct 435 LTLFMILGFTAFGVWRCRVEHIAHISKDAWKNDLKPQDVPGLDFFDMHTIQNATNNFSLS 494 Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG+G FG V G+ +AVK L + G Q + + EI ++ L H +++ Sbjct 495 NKLGQGGFGSVYKGKLQ-----DGKEIAVKRLSSSSG-QGKEEFMNEIVLISKLQHRNLV 548 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016 + GCC ++ EK L+ E++ SL +L R I + Q I G+ YLH Sbjct 549 RVLGCCIEEEEK--LLIYEFMVNKSLDTFLFDSRKRLEIDWPKRFDIIQGIARGLLYLHH 606 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRDL N+LLD KI DFGLA+ + +G EY + + +PE Sbjct 607 DSRLRVIHRDLKVSNILLDEKMNPKISDFGLAR-MYQGTEYQDNTRRVVGTLGYMSPEYA 665 Query 1074 KEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 F SD++SFGV + E+++ S S + LI A + R +LL++ Sbjct 666 WTGMFSEKSDIYSFGVLMLEIISGEKISRFSYGVEGKTLIAYAWESWSEYRGIDLLDQDL 725 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182 + C + + + RP L+ +L T + + P+ Sbjct 726 ADSCHPLEVGRCIQIGLLCVQHQPADRPNTLELLAMLTTTSDLPSPKQPT 775 Score = 235 bits (599), Expect = 2e-63, Method: Composition-based stats. Identities = 53/247 (21%), Positives = 95/247 (38%), Gaps = 45/247 (18%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L+ + + + + LGQG +VY+G+L+ Sbjct 476 LDFFDMHTIQNATNNFSLSNKLGQGGFGSVYKGKLQDGK--------------------- 514 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + +K L S F L+S++ H +L V G C+ E +++ E++ + Sbjct 515 ----EIAVKRLSSSSGQGKEEFMNEIVLISKLQHRNLVRVLGCCIEEEEKLLIYEFMVNK 570 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748 LD +L R + + W + + Q +A L YL + ++H ++ NILL Sbjct 571 SLDTFLFDSRKRLEIDWPKRFDIIQGIARGLLYLHHDSRLRVIHRDLKVSNILLDEK--- 627 Query 749 EGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGA 802 K+SD G+ E + V + +++PE G S D + FG Sbjct 628 ----MNPKISDFGLARMYQGTEYQDNTRRVVGTLGYMSPEYAWTGM--FSEKSDIYSFGV 681 Query 803 TLLEICF 809 +LEI Sbjct 682 LMLEIIS 688 >sp|P42687|SPK1_GIRTI Tyrosine-protein kinase SPK-1 OS=Girardia tigrina OX=6162 PE=2 SV=1 Length=497 Score = 252 bits (643), Expect = 7e-72, Method: Composition-based stats. Identities = 81/474 (17%), Positives = 166/474 (35%), Gaps = 86/474 (18%) Query 431 SHYLCHEVAPPRLVM---SIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTV 487 S+Y+ + P+ V I+ K+ + G Y+I S L+V Sbjct 86 SNYVSKQDGSPQSVEAWREIQRW-----EAEKSLMKIGLQKGTYIIRPSRKE-NSYALSV 139 Query 488 AQRSQAPDGMQSLRLRKFPIE--QQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCF 545 + + ++ F I+ Q + R+FP++ L + + G+ Sbjct 140 RDFDEK---KKICIVKHFQIKTLQDEKGISYSVNIRNFPNILTLIQFYEKNGI--GNTHI 194 Query 546 SLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605 L ++ + ++++ I L+ +G+G +V+ Sbjct 195 PLTDPMPDNYQ---------------PPVHFQDI---EINRENIEILNEIGRGFFGSVHR 236 Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV 665 + G+ V K+L S + F A +M ++ Sbjct 237 AKW-------------------------GRSYEVAAKMLQSSKAE-REKFVLEAKIMHKL 270 Query 666 SHTHLAFVHGVCVRGP--ENIMVTEYVEHGPLDVWLRRERGHVP-MAWKMVVAQQLASAL 722 H + + GVC +++ EY+++G L +L+ G + + + +++ + Sbjct 271 RHRKIVELLGVCTEPQDMPMLIIVEYMKNGSLKEYLKTPDGKKTNLNQMVHMMAEISEGM 330 Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGALSREERVERI 776 +YLE++ +VH ++ NIL+A K++D G+ LG ++ Sbjct 331 AYLESEKVVHRDLRADNILVANDLTR-------KVADFGLTELTDGSLGDQEKKTLRFPY 383 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836 W APE ++ D W +G + EI +P E + +R+P P Sbjct 384 KWTAPEAAKSKV--FTSKSDVWSYGIVMFEILTWASSPYPDIPAKEVIEKVSKGYRMPNP 441 Query 837 -------SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 CP + + C P +RP+F + + L L + + Sbjct 442 EKFITGVCCPDEIYKIMIWCWDANPEKRPTFLVLQEKMDLLIVDTLTNNAYYSH 495 Score = 250 bits (638), Expect = 3e-71, Method: Composition-based stats. Identities = 82/302 (27%), Positives = 132/302 (44%), Gaps = 31/302 (10%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 + ++ ++ + ++G G FG V + G VA Sbjct 193 HIPLTDPMPDNYQPPVHFQDIEINRENIEILNEIGRGFFGSVHRAKW-----GRSYEVAA 247 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K L R + E I+ L H I++ G C + + + +++EY+ GSL++Y Sbjct 248 KML--QSSKAEREKFVLEAKIMHKLRHRKIVELLGVCTEPQDMPMLIIVEYMKNGSLKEY 305 Query 990 LP---RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 L L Q++ +I EGMAYL ++ +HRDL A N+L+ ND K+ DFGL Sbjct 306 LKTPDGKKTNLNQMVHMMAEISEGMAYLESEKVVHRDLRADNILVANDLTRKVADFGL-T 364 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 + +G + ++ P W APE K F SDVWS+G+ ++E+LT Sbjct 365 ELTDGSLGDQEKKTLRFPYKWTAPEAAKSKVFTSKSDVWSYGIVMFEILT---------- 414 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDK------CPCEVYHLMKNCWETEASFRP 1160 + + E + +G R+P P+K CP E+Y +M CW+ RP Sbjct 415 ----WASSPYPDIPAKEVIEKVSKGYRMPNPEKFITGVCCPDEIYKIMIWCWDANPEKRP 470 Query 1161 TF 1162 TF Sbjct 471 TF 472 >sp|P97523|MET_RAT Hepatocyte growth factor receptor OS=Rattus norvegicus OX=10116 GN=Met PE=1 SV=1 Length=1382 Score = 266 bits (681), Expect = 8e-72, Method: Composition-based stats. Identities = 88/285 (31%), Positives = 138/285 (48%), Gaps = 19/285 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G GHFG V + DG AVK+L + S + E I++ H Sbjct 1080 HFNEVIGRGHFGCVYHGTLLDS-DGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHP 1138 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLH 1015 +++ G C + E S +V+ Y+ G LR+++ H+ + L+ F Q+ +GM YL Sbjct 1139 NVLSLLGICL-RSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLV 1197 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPVFWYAPECLK 1074 ++ ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV W A E L+ Sbjct 1198 SKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQ 1257 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 KF SDVWSFGV L+EL+T + +T L +G RL Sbjct 1258 TQKFTTKSDVWSFGVLLWELMTRGAP--------------PYPDVNTFDITIYLLQGRRL 1303 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +P+ CP +Y +M CW +A RP+ L+ + ++ + G+ Sbjct 1304 LQPEYCPDALYEVMLKCWHPKAEMRPSVSELVSRISSIFSTFIGE 1348 Score = 228 bits (581), Expect = 1e-59, Method: Composition-based stats. Identities = 63/328 (19%), Positives = 120/328 (37%), Gaps = 42/328 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHH 649 +G+G VY G L G+++ +K L+ + Sbjct 1081 FNEVIGRGHFGCVYHGTLLDSD---------------------GKKIHCAVKSLNRITDI 1119 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPM 708 + F +M SH ++ + G+C+R ++V Y++HG L ++R E + + Sbjct 1120 EEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTV 1179 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A + YL +K VH ++ RN +L +K++D G+ Sbjct 1180 KDLIGFGLQVAKGMKYLVSKKFVHRDLAARNCMLDEK-------FTVKVADFGLARDMYD 1232 Query 769 REERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +E + W+A E L +T D W FG L E+ G P + Sbjct 1233 KEYYSVHNKTGAKLPVKWMALESLQT--QKFTTKSDVWSFGVLLWELMTRGAPPYPDVNT 1290 Query 821 SEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + RL PE L + +C + RPS ++ ++ + + + Sbjct 1291 FDITIYLLQGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSVSELVSRISSIFSTFIGEHY 1350 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + V L +D +G Sbjct 1351 VHVNATYVNVKCVAPYPSLLPSQDNIDG 1378 >sp|Q91738|FAK1_XENLA Focal adhesion kinase 1 OS=Xenopus laevis OX=8355 GN=ptk2 PE=2 SV=2 Length=1068 Score = 264 bits (674), Expect = 8e-72, Method: Composition-based stats. Identities = 95/315 (30%), Positives = 146/315 (46%), Gaps = 24/315 (8%) Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPT 919 + + + + + + + ++ R +GEG FG V Y P Sbjct 399 ETDDYAEIIDEEDTYTMPSKSYGLDEAGDYEIQRDRIELGRCIGEGQFGDVHQGVYMSPE 458 Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979 N VA+K K R + QE +R H HI+K G E + ++ME Sbjct 459 NPA--MAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVI---TENPVWIIME 513 Query 980 YVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037 LG LR +L ++S+ LA L+L++ Q+ +AYL ++ ++HRD+AARNVL+ + V Sbjct 514 LCTLGELRSFLQVRKYSLDLASLILYSYQLSTALAYLESKRFVHRDIAARNVLVSSSDCV 573 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 K+GDFGL++ + + Y G P+ W APE + +F ASDVW FGV ++E+L + Sbjct 574 KLGDFGLSRYMEDS--TYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMY 631 Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157 + + +E GERLP P CP +Y LM CW + S Sbjct 632 GVKPFQ--------------GVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPS 677 Query 1158 FRPTFENLIPILKTV 1172 RP F L L T+ Sbjct 678 RRPRFTELKAQLSTI 692 Score = 237 bits (604), Expect = 8e-63, Method: Composition-based stats. Identities = 69/308 (22%), Positives = 125/308 (41%), Gaps = 39/308 (13%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 ++ L + + + + I +G+G +V++G V Sbjct 416 PSKSYGLDEAGDYEIQRDRIELGRCIGEGQFGDVHQG---------------------VY 454 Query 630 GRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 + V +K D F + A M Q H H+ + GV P ++ E Sbjct 455 MSPENPAMAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENP-VWIIME 513 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 G L +L+ + + +A ++ + QL++AL+YLE+K VH ++ RN+L++ Sbjct 514 LCTLGELRSFLQVRKYSLDLASLILYSYQLSTALAYLESKRFVHRDIAARNVLVS----- 568 Query 749 EGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGAT 803 +S +KL D G+ I W+APE + ++A D W FG Sbjct 569 --SSDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI--NFRRFTSASDVWMFGVC 624 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRT 861 + EI G P Q ++ + R +P P L +L ++C Y+P++RP F Sbjct 625 MWEILMYGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTE 684 Query 862 ILRDLTRL 869 + L+ + Sbjct 685 LKAQLSTI 692 Score = 38.5 bits (88), Expect = 0.50, Method: Composition-based stats. Identities = 33/198 (17%), Positives = 71/198 (36%), Gaps = 39/198 (20%) Query 120 PAVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSTEEEIHHF 179 P ++ Q + D + + ++Q K+++++++A + Sbjct 117 PEEWKYELRIRYLPKGFVNQFTE--DKPTLNFFYQQVKNDYMSEIADQVD---------- 164 Query 180 KNESLGMAFLHLCHL-------ALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTRL 232 + +L + L + AL E + K K P+S ++ + R Sbjct 165 QEIALKLGCLEIRRSYGEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTL--RK 222 Query 233 RLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAP--RFGTERVP-------VCHLRLL 283 ++ FR+F L+++ ++K+ E L+P R+ E + + L Sbjct 223 LIQQTFRQF------ANLNREESILKF---FEILSPVYRYDKECFKCALGSSWIISVELA 273 Query 284 AQAEGEPCYIRDSGVAPT 301 E Y+ D G PT Sbjct 274 IGPEEGISYLTDKGSNPT 291 >sp|F1N9Y5|KSYK_CHICK Tyrosine-protein kinase SYK OS=Gallus gallus OX=9031 GN=SYK PE=1 SV=2 Length=613 Score = 255 bits (651), Expect = 8e-72, Method: Composition-based stats. Identities = 96/272 (35%), Positives = 138/272 (51%), Gaps = 21/272 (8%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHII 960 +LG G+FG V Y + VAVK LK + P + +E ++++ L + +I+ Sbjct 354 ELGSGNFGTVKKGFYKMKKGA--KPVAVKILKNESNDPAIKDELLREANVMQQLDNPYIV 411 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019 + G CE ++ LVME LG L +L ++ + + Q+ GM YL ++ Sbjct 412 RMIGICE---AEAWMLVMEMAELGPLNKFLQKNRHVTEKNITELVHQVSMGMKYLEENNF 468 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDLAARNVLL KI DFGL+KA+ YY+ + G PV WYAPEC+ YKF Sbjct 469 VHRDLAARNVLLVTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECMNFYKFS 528 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SDVWSFGV ++E ++ M + +++ERGER+ P+ Sbjct 529 SKSDVWSFGVLMWEAFSYGQK--------------PYKGMKGGEVAQMIERGERMECPEA 574 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 CP EVY LMK CW RP F + L+ Sbjct 575 CPVEVYDLMKLCWTYNVDDRPGFVAVELRLRN 606 Score = 228 bits (580), Expect = 3e-62, Method: Composition-based stats. Identities = 102/563 (18%), Positives = 183/563 (33%), Gaps = 135/563 (24%) Query 380 FRDITHVVLKEHCVSIHRQDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVA 439 F D+ +++E+ LE ++ S+ L +L A ++H E Sbjct 119 FEDLKENLIREYVKQTWNLQGHALEQAIISQKPQLE---------KLIATTAH----EKM 165 Query 440 PPRLVMSIRDGIHGPLLEPFVQAKLR---PEDGLYLIHWSTSHPYRLILTVAQRSQAPDG 496 P HG + + ++ +G +LI S+ L + DG Sbjct 166 P---------WFHGRISREESEHRILIGSRNNGKFLIRERDSN-GSYALCL-----LNDG 210 Query 497 MQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPG 556 + + I++ + G+ F ++ +L + L C Sbjct 211 K----VLHYRIDRDKTGKLSIPDGKRFDTLWQLVEHYS---YKPDGLLRVLSIPCPRHGS 263 Query 557 ETSNLI------------------------------IMRGAR---------------ASP 571 E+ N++ +++ AR Sbjct 264 ESDNVVFDTRPLPGTPSKLQTPIGAPSDDQTPFNPYVLQRARGLIGAEKGDQREALPMDT 323 Query 572 RTLNLSQLSFHRVDQKEITQLSH--------LGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 + K +T LG G V +G +++ P Sbjct 324 EVYESPYADPDEIKPKNVTLDRKLLTLEEGELGSGNFGTVKKGFYKMKKGAKP------- 376 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 V +K+L +D I A++M Q+ + ++ + G+C Sbjct 377 ---------------VAVKILKNESNDPAIKDELLREANVMQQLDNPYIVRMIGIC-EAE 420 Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 ++V E E GPL+ +L++ R HV + Q++ + YLE N VH ++ RN+L Sbjct 421 AWMLVMEMAELGPLNKFLQKNR-HVTEKNITELVHQVSMGMKYLEENNFVHRDLAARNVL 479 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTA 794 L T + K+SD G+ + E + + W APEC+ S+ Sbjct 480 L-------VTQHYAKISDFGLSKALSADENYYKAQSHGKWPVKWYAPECM--NFYKFSSK 530 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYE 852 D W FG + E G+ P + E +R R+ PE ++ L C TY Sbjct 531 SDVWSFGVLMWEAFSYGQKPYKGMKGGEVAQMIERGERMECPEACPVEVYDLMKLCWTYN 590 Query 853 PTQRPSFRTILRDLTRLQPHNLA 875 RP F + L Sbjct 591 VDDRPGFVAVELRLRNYYYDISH 613 Score = 36.6 bits (83), Expect = 1.8, Method: Composition-based stats. Identities = 22/107 (21%), Positives = 36/107 (34%), Gaps = 15/107 (14%) Query 453 GPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQ 509 G + + L DGLYL+ S ++ L++A ++ + IE+ Sbjct 17 GNITREEAEEYLMQGGMSDGLYLLRQSRNYLGGFALSLAY---------GRKVHHYTIER 67 Query 510 QDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPG 556 + G+S S EL A LR+ PG Sbjct 68 ELSGTYAIAGGKSHASPAELINYHSEE---ADGLICLLRKSFNRPPG 111 >sp|Q3U1V8|M3K9_MOUSE Mitogen-activated protein kinase kinase kinase 9 OS=Mus musculus OX=10090 GN=Map3k9 PE=2 SV=2 Length=1077 Score = 264 bits (675), Expect = 9e-72, Method: Composition-based stats. Identities = 92/293 (31%), Positives = 135/293 (46%), Gaps = 41/293 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP---QHRSGWKQEIDILRTLYHEHI 959 +G G FGKV + G+ VAVKA + D Q +QE + L H +I Sbjct 143 IGIGGFGKVYRAFWA------GDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPNI 196 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 I +G C E +L LVME+ G L L I L+ +A QI GM YLH + Sbjct 197 IALRGVCLK--EPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIARGMNYLHDEAI 254 Query 1018 -HYIHRDLAARNVLL-------D-NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 IHRDL + N+L+ D +++++KI DFGLA+ + + W Sbjct 255 VPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLAR-----EWHRTTKMSAAGTYAWM 309 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 APE ++ F SDVWS+GV L+ELLT P + ++ + +A G + Sbjct 310 APEVIRASMFSKGSDVWSYGVLLWELLTG-----EVPFRGIDGLAVAYG---------VA 355 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 LP P CP LM++CW + RP+F +++ L T+ E + P Sbjct 356 MNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTSILDQLTTIEESGFFEMP 408 Score = 237 bits (605), Expect = 5e-63, Method: Composition-based stats. Identities = 90/483 (19%), Positives = 169/483 (35%), Gaps = 75/483 (16%) Query 513 AFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPR 572 + G + ++ L +GD+ + + SN + R A +S Sbjct 55 EYEAAGEDELTLRLGDVVEVLSKDSQVSGDEGWWTGQLNQRVGIFPSNYVTPRSAFSSRC 114 Query 573 TLN------LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 + +D E+T +G G VY + Sbjct 115 QPGAEDPSCYPPIQLLEIDFAELTLEEIIGIGGFGKVYRAFWAGD--------------- 159 Query 627 LVPGRDRGQELRVVLKVL----DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 V +K D + A L + + H ++ + GVC++ P Sbjct 160 -----------EVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPN 208 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRN 739 +V E+ GPL+ L +R +P + A Q+A ++YL ++ ++H ++ N Sbjct 209 LCLVMEFARGGPLNRVLSGKR--IPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSN 266 Query 740 IL-LARLGLAEGTSPFIKLSDPGVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMD 796 IL L ++ + ++ +K++D G+ ++ W+APE + A+ S D Sbjct 267 ILILQKVENGDLSNKILKITDFGLAREWHRTTKMSAAGTYAWMAPEVIR--ASMFSKGSD 324 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEP 853 W +G L E+ GE P + + + +P A L C +P Sbjct 325 VWSYGVLLWELL-TGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDP 383 Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 RPSF +IL LT ++ ++ + D + ++R Sbjct 384 HSRPSFTSILDQLTTIEESGFFEMPKDSFHCLQDDWKHEIQEMFDQLRA----------- 432 Query 914 YCYDPTNDGTGEM----VAV--KALKADCGPQHRSGWKQEIDIL-RTLYHEHIIKYKGCC 966 T E A+ K + + + ++EIDIL R L +II C Sbjct 433 ---KEKELRTWEEELTRAALQQKNQEELLRRREQELAEREIDILEREL---NII-IHQLC 485 Query 967 EDQ 969 +++ Sbjct 486 QEK 488 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens OX=9606 GN=MAP3K11 PE=1 SV=1 Length=847 Score = 260 bits (665), Expect = 9e-72, Method: Composition-based stats. Identities = 92/293 (31%), Positives = 128/293 (44%), Gaps = 41/293 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR---SGWKQEIDILRTLYHEHI 959 +G G FGKV + GE+VAVKA + D +QE + L H +I Sbjct 123 IGIGGFGKVYRGSWR------GELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNI 176 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 I K C + E +L LVMEY G L L + L+ +A QI GM YLH + Sbjct 177 IALKAVCLE--EPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLHCEAL 234 Query 1018 -HYIHRDLAARNVLL--------DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 IHRDL + N+LL + +KI DFGLA+ + + W Sbjct 235 VPVIHRDLKSNNILLLQPIESDDMEHKTLKITDFGLAR-----EWHKTTQMSAAGTYAWM 289 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 APE +K F SDVWSFGV L+ELLT P + ++ + +A G Sbjct 290 APEVIKASTFSKGSDVWSFGVLLWELLTG-----EVPYRGIDCLAVAYGVAVN------- 337 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 LP P CP LM +CW + RP F +++ L+ + + + P Sbjct 338 --KLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLREMP 388 Score = 219 bits (559), Expect = 5e-58, Method: Composition-based stats. Identities = 71/314 (23%), Positives = 120/314 (38%), Gaps = 36/314 (11%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +E+ +G G VY G R E + DED V Sbjct 113 SFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISV---------------- 156 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 A + + A L + ++H ++ + VC+ P +V EY GPL L R Sbjct 157 ------TAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRR- 209 Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSP-FIKLSDP 760 VP + A Q+A + YL + ++H ++ NILL + ++ +K++D Sbjct 210 -VPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIESDDMEHKTLKITDF 268 Query 761 GVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 G+ ++ W+APE + A++ S D W FG L E+ GE P + Sbjct 269 GLAREWHKTTQMSAAGTYAWMAPEVIK--ASTFSKGSDVWSFGVLLWELL-TGEVPYRGI 325 Query 819 SPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + + +P A L + C +P +RP F +IL+ L L+ L Sbjct 326 DCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLR 385 Query 876 DVLTVNPDSPASDP 889 ++ + S Sbjct 386 EMPRDSFHSMQEGW 399 >sp|Q8MY86|FGFR1_DUGJA Fibroblast growth factor receptor 1 OS=Dugesia japonica OX=6161 GN=FGFR1 PE=2 SV=1 Length=854 Score = 260 bits (665), Expect = 9e-72, Method: Composition-based stats. Identities = 91/327 (28%), Positives = 158/327 (48%), Gaps = 33/327 (10%) Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPTNDGTGE 925 L+ + + ++ + ++ + LGEG FG V D N Sbjct 521 YGLRKSSSFEFFSLYEFPCDAKWEFPREKLKITNKKLGEGAFGMVYEGIANDIGNRSNPI 580 Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 VAVK ++ D + + +E++I++ + H ++I+ G C +G L++++E P G Sbjct 581 KVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRHPNVIQLLGLCTQKG--PLRVIVELAPYG 638 Query 985 SLRDYLPR------------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032 +LRD++ + + L ++ QI GM YL ++ +HRDL+ARN+L+ Sbjct 639 NLRDFVRAKNKKYSKSKKIIGNFTSSILCTYSLQIARGMTYLASRSVVHRDLSARNILVG 698 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 +KI DFGL + V YYR + DG PV W APE L E K+ SDVWS+G+ L+ Sbjct 699 EHFEMKIADFGLTRIVDY---YYRKKTDGILPVKWMAPEALLEKKYTTKSDVWSYGILLW 755 Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152 E+ T DS + ++ +L+ +G + P+P+ E+Y LM++CW Sbjct 756 EIFTLGDS--------------PYSAILPEKVVDLIRKGFQNPKPELANFEIYRLMQHCW 801 Query 1153 ETEASFRPTFENLIPILKTVHEKYQGQ 1179 + RP F ++ IL + ++ + Sbjct 802 SLSSENRPNFFEIVEILIDIIQRIDDE 828 Score = 219 bits (559), Expect = 5e-58, Method: Composition-based stats. Identities = 70/369 (19%), Positives = 133/369 (36%), Gaps = 52/369 (14%) Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEI------TQLSHLGQGTRTNVYEGRLR 609 ++L + G R S S F + E LG+G VYEG Sbjct 512 SGNNSLSLKYGLRKSSSFEFFSLYEFPCDAKWEFPREKLKITNKKLGEGAFGMVYEGIAN 571 Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQV-SH 667 G +R ++V +K++ D F + +M + H Sbjct 572 DIG-------------------NRSNPIKVAVKMMRDDFSDSNVHDFVKEMEIMKHIGRH 612 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER----------GHVPMAWKMVVAQQ 717 ++ + G+C + ++ E +G L ++R + G+ + + Q Sbjct 613 PNVIQLLGLCTQKGPLRVIVELAPYGNLRDFVRAKNKKYSKSKKIIGNFTSSILCTYSLQ 672 Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--GALSREERVE- 774 +A ++YL ++++VH ++ RNIL+ G +K++D G+ R++ Sbjct 673 IARGMTYLASRSVVHRDLSARNILV-------GEHFEMKIADFGLTRIVDYYYRKKTDGI 725 Query 775 -RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833 + W+APE L +T D W +G L EI G++P + P + ++ + Sbjct 726 LPVKWMAPEALLE--KKYTTKSDVWSYGILLWEIFTLGDSPYSAILPEKVVDLIRKGFQN 783 Query 834 PEPSCPQL--ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV 891 P+P L C + RP+F I+ L + + S + + Sbjct 784 PKPELANFEIYRLMQHCWSLSSENRPNFFEIVEILIDIIQRIDDEPEENIYHSELNYLKM 843 Query 892 FHKRYLKKI 900 K Sbjct 844 ESDYLEPKC 852 >sp|Q61527|ERBB4_MOUSE Receptor tyrosine-protein kinase erbB-4 OS=Mus musculus OX=10090 GN=Erbb4 PE=1 SV=5 Length=1308 Score = 266 bits (679), Expect = 9e-72, Method: Composition-based stats. Identities = 99/272 (36%), Positives = 140/272 (51%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + VA+K L GP+ + E I+ ++ H H+++ Sbjct 724 LGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRL 783 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C +QLV + +P G L DY+ H IG LL + QI +GM YL + + Sbjct 784 LGVCLSPT---IQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV 840 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ + VKI DFGLA+ + EG E + G P+ W A EC+ KF + Sbjct 841 HRDLAARNVLVKSPNHVKITDFGLARLL-EGDEKEYNADGGKMPIKWMALECIHYRKFTH 899 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T G + + +LLE+GERLP+P C Sbjct 900 QSDVWSYGVTIWELMTFG--------------GKPYDGIPTREIPDLLEKGERLPQPPIC 945 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW +A RP F+ L + Sbjct 946 TIDVYMVMVKCWMIDADSRPKFKELAAEFSRM 977 Score = 242 bits (617), Expect = 6e-64, Method: Composition-based stats. Identities = 67/338 (20%), Positives = 131/338 (39%), Gaps = 39/338 (12%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P +Q + + E+ ++ LG G VY+G EG Sbjct 699 TPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETV-------------- 744 Query 630 GRDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ V +K+L+ + + F + A +M+ + H HL + GVC+ P +VT+ Sbjct 745 ------KIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCL-SPTIQLVTQ 797 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + HG L ++ + ++ + Q+A + YLE + LVH ++ RN+L+ Sbjct 798 LMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPN-- 855 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 +K++D G+ + + I W+A EC+ + D W +G Sbjct 856 -----HVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIH--YRKFTHQSDVWSYGV 908 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860 T+ E+ G P E ++ RLP+P + + +C + RP F+ Sbjct 909 TIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFK 968 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898 + + +R+ ++ D K + Sbjct 969 ELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQN 1006 >sp|Q05609|CTR1_ARATH Serine/threonine-protein kinase CTR1 OS=Arabidopsis thaliana OX=3702 GN=CTR1 PE=1 SV=1 Length=821 Score = 260 bits (664), Expect = 1e-71, Method: Composition-based stats. Identities = 77/333 (23%), Positives = 142/333 (43%), Gaps = 37/333 (11%) Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR---DLGEGHFG 909 P Q + + + ++ + + + +G G FG Sbjct 504 PPQNMMRASNQIEAAPMNAPPISQPVPNRANRELGLDGDDMDIPWCDLNIKEKIGAGSFG 563 Query 910 KVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968 V + ++ VAVK L + D + + + +E+ I++ L H +I+ + G Sbjct 564 TVHRAEWHGSD------VAVKILMEQDFHAERVNEFLREVAIMKRLRHPNIVLFMGAVTQ 617 Query 969 QGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQH--YIHR 1022 +L +V EY+ GSL L R + + L A + +GM YLH ++ +HR Sbjct 618 P--PNLSIVTEYLSRGSLYRLLHKSGAREQLDERRRLSMAYDVAKGMNYLHNRNPPIVHR 675 Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082 DL + N+L+D VK+ DFGL++ + + + +P W APE L++ S Sbjct 676 DLKSPNLLVDKKYTVKVCDFGLSRL--KASTFLSSKSAAGTPE-WMAPEVLRDEPSNEKS 732 Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE-RGERLPRPDKCP 1141 DV+SFGV L+EL T + G + ++ + + +RL P Sbjct 733 DVYSFGVILWELAT---------------LQQPWGNLNPAQVVAAVGFKCKRLEIPRNLN 777 Query 1142 CEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 +V +++ CW E RP+F ++ +L+ + + Sbjct 778 PQVAAIIEGCWTNEPWKRPSFATIMDLLRPLIK 810 Score = 244 bits (623), Expect = 2e-66, Method: Composition-based stats. Identities = 63/297 (21%), Positives = 119/297 (40%), Gaps = 45/297 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + ++ +G G+ V+ G ++ V + + Sbjct 546 IPWCDLNIKEKIGAGSFGTVHRAEW------------------------HGSDVAVKILM 581 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702 H + F ++M ++ H ++ G + P +VTEY+ G L L + Sbjct 582 EQDFHAERVNEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKSG 641 Query 703 -RGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R + ++ +A +A ++YL N+N +VH ++ N+L+ + +K+ D Sbjct 642 AREQLDERRRLSMAYDVAKGMNYLHNRNPPIVHRDLKSPNLLVDKK-------YTVKVCD 694 Query 760 PGVGLGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ LS + W+APE L + + D + FG L E+ + P Sbjct 695 FGLSRLKASTFLSSKSAAGTPEWMAPEVLRDEPS--NEKSDVYSFGVILWELATL-QQPW 751 Query 816 QSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + +P++ F ++ +P PQ+A + C T EP +RPSF TI+ L L Sbjct 752 GNLNPAQVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNEPWKRPSFATIMDLLRPL 808 >sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kinase 11 OS=Rattus norvegicus OX=10116 GN=Map3k11 PE=1 SV=1 Length=850 Score = 260 bits (665), Expect = 1e-71, Method: Composition-based stats. Identities = 92/293 (31%), Positives = 128/293 (44%), Gaps = 41/293 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR---SGWKQEIDILRTLYHEHI 959 +G G FGKV + GE+VAVKA + D +QE + L H +I Sbjct 124 IGIGGFGKVYRGSWR------GELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNI 177 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 I K C + E +L LVMEY G L L + L+ +A QI GM YLH + Sbjct 178 IALKAVCLE--EPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLHCEAL 235 Query 1018 -HYIHRDLAARNVLL--------DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 IHRDL + N+LL + +KI DFGLA+ + + W Sbjct 236 VPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAR-----EWHKTTQMSAAGTYAWM 290 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 APE +K F SDVWSFGV L+ELLT P + ++ + +A G Sbjct 291 APEVIKASTFSKGSDVWSFGVLLWELLTG-----EVPYRGIDCLAVAYGVAVN------- 338 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 LP P CP LM +CW + RP F +++ L+ + + + P Sbjct 339 --KLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLREMP 389 Score = 219 bits (558), Expect = 6e-58, Method: Composition-based stats. Identities = 71/314 (23%), Positives = 119/314 (38%), Gaps = 36/314 (11%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +E+ +G G VY G R E + DED V Sbjct 114 SFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISV---------------- 157 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 A + + A L + ++H ++ + VC+ P +V EY GPL L R Sbjct 158 ------TAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRR- 210 Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSP-FIKLSDP 760 VP + A Q+A + YL + ++H ++ NILL + + +K++D Sbjct 211 -VPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDF 269 Query 761 GVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 G+ ++ W+APE + A++ S D W FG L E+ GE P + Sbjct 270 GLAREWHKTTQMSAAGTYAWMAPEVIK--ASTFSKGSDVWSFGVLLWELL-TGEVPYRGI 326 Query 819 SPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + + +P A L + C +P +RP F +IL+ L L+ L Sbjct 327 DCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLR 386 Query 876 DVLTVNPDSPASDP 889 ++ + S Sbjct 387 EMPRDSFHSMQEGW 400 >sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase kinase 11 OS=Mus musculus OX=10090 GN=Map3k11 PE=1 SV=1 Length=850 Score = 260 bits (665), Expect = 1e-71, Method: Composition-based stats. Identities = 92/293 (31%), Positives = 128/293 (44%), Gaps = 41/293 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR---SGWKQEIDILRTLYHEHI 959 +G G FGKV + GE+VAVKA + D +QE + L H +I Sbjct 124 IGIGGFGKVYRGSWR------GELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNI 177 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 I K C + E +L LVMEY G L L + L+ +A QI GM YLH + Sbjct 178 IALKAVCLE--EPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLHCEAL 235 Query 1018 -HYIHRDLAARNVLL--------DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 IHRDL + N+LL + +KI DFGLA+ + + W Sbjct 236 VPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAR-----EWHKTTQMSAAGTYAWM 290 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 APE +K F SDVWSFGV L+ELLT P + ++ + +A G Sbjct 291 APEVIKASTFSKGSDVWSFGVLLWELLTG-----EVPYRGIDCLAVAYGVAVN------- 338 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 LP P CP LM +CW + RP F +++ L+ + + + P Sbjct 339 --KLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLREMP 389 Score = 219 bits (558), Expect = 6e-58, Method: Composition-based stats. Identities = 71/314 (23%), Positives = 119/314 (38%), Gaps = 36/314 (11%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +E+ +G G VY G R E + DED V Sbjct 114 SFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISV---------------- 157 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 A + + A L + ++H ++ + VC+ P +V EY GPL L R Sbjct 158 ------TAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRR- 210 Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSP-FIKLSDP 760 VP + A Q+A + YL + ++H ++ NILL + + +K++D Sbjct 211 -VPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDF 269 Query 761 GVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 G+ ++ W+APE + A++ S D W FG L E+ GE P + Sbjct 270 GLAREWHKTTQMSAAGTYAWMAPEVIK--ASTFSKGSDVWSFGVLLWELL-TGEVPYRGI 326 Query 819 SPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + + +P A L + C +P +RP F +IL+ L L+ L Sbjct 327 DCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLR 386 Query 876 DVLTVNPDSPASDP 889 ++ + S Sbjct 387 EMPRDSFHSMQEGW 400 >sp|Q9SIB6|PBL6_ARATH Probable serine/threonine-protein kinase PBL6 OS=Arabidopsis thaliana OX=3702 GN=PBL6 PE=2 SV=1 Length=424 Score = 249 bits (635), Expect = 1e-71, Method: Composition-based stats. Identities = 77/287 (27%), Positives = 127/287 (44%), Gaps = 18/287 (6%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 K LGEG FGKV + N ++VA+K L + G Q + E+ L Sbjct 97 NFKSDCFLGEGGFGKVYKGFIEKIN----QVVAIKQLDRN-GAQGIREFVVEVLTLSLAD 151 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEG 1010 H +++K G C + ++ LV EY+PLGSL ++L ++ + + A G Sbjct 152 HPNLVKLIGFCAEGVQR--LLVYEYMPLGSLDNHLHDLPSGKNPLAWNTRMKIAAGAARG 209 Query 1011 MAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH I+RDL N+L+D K+ DFGLAK P G E + V + Sbjct 210 LEYLHDTMKPPVIYRDLKCSNILIDEGYHAKLSDFGLAKVGPRGSETH-VSTRVMGTYGY 268 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQMTVLR-LT 1125 AP+ + + SDV+SFGV L EL+T + + T+ L+ A + Sbjct 269 CAPDYALTGQLTFKSDVYSFGVVLLELITGRKAYDNTRTRNHQSLVEWANPLFKDRKNFK 328 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 ++++ P + + + C + + S RP +++ L + Sbjct 329 KMVDPLLEGDYPVRGLYQALAIAAMCVQEQPSMRPVIADVVMALDHL 375 Score = 221 bits (562), Expect = 9e-62, Method: Composition-based stats. Identities = 70/345 (20%), Positives = 115/345 (33%), Gaps = 66/345 (19%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +T +LS V LG+G VY+G + Sbjct 82 KAQTFTFEELS---VSTGNFKSDCFLGEGGFGKVYKGFIEKINQ---------------- 122 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 V +K LD + F +S H +L + G C G + ++V EY Sbjct 123 --------VVAIKQLDRNGAQGIREFVVEVLTLSLADHPNLVKLIGFCAEGVQRLLVYEY 174 Query 690 VEHGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLA 743 + G LD L G P+AW +M +A A L YL + +++ ++ NIL+ Sbjct 175 MPLGSLDNHLHDLPSGKNPLAWNTRMKIAAGAARGLEYLHDTMKPPVIYRDLKCSNILID 234 Query 744 RLGLAEGTSPFIKLSDPGVGL-GALSREERV-----ERIPWLAPECLPGGANSLSTAMDK 797 KLSD G+ G E V + AP+ G L+ D Sbjct 235 E-------GYHAKLSDFGLAKVGPRGSETHVSTRVMGTYGYCAPDYALTG--QLTFKSDV 285 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQ------RQHRLPEPSCPQLA--------- 842 + FG LLE+ +A +R+ + + + + P L Sbjct 286 YSFGVVLLELITGRKAYDNTRTRNHQSLVEWANPLFKDRKNFKKMVDPLLEGDYPVRGLY 345 Query 843 ---TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884 + + C+ +P+ RP ++ L L D+ Sbjct 346 QALAIAAMCVQEQPSMRPVIADVVMALDHLASSKYDRSHRQKQDN 390 >sp|Q7T6X2|YR826_MIMIV Putative serine/threonine-protein kinase/receptor R826 OS=Acanthamoeba polyphaga mimivirus OX=212035 GN=MIMI_R826 PE=3 SV=2 Length=1657 Score = 266 bits (681), Expect = 1e-71, Method: Composition-based stats. Identities = 80/326 (25%), Positives = 135/326 (41%), Gaps = 33/326 (10%) Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911 + S + Q H + S V + +K +G G +G V Sbjct 1354 DMDTDNSTFSARVPHQAYQYHAAIENNERYLTSAGLCSWVINYDEIKMGEQIGLGSYGVV 1413 Query 912 SLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970 + + VA+K +K H G ++EI L+ L+H +II G + Sbjct 1414 YRGKWKNVD------VAIKKFIKQKIDENHLLGIREEIAFLKKLHHPNIITMVGASLKK- 1466 Query 971 EKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHA--QHYIHRDLAA 1026 ++ +V EY+ G+LRD + + Q + I +G++YLH+ IHRD+ Sbjct 1467 -PNICIVTEYMAKGNLRDAMRTCTPKLEWHQKIKILVNIAKGISYLHSFDPPIIHRDIKP 1525 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 N+L+D + VKI DFG A+ E R W APE ++ + DV+S Sbjct 1526 SNILIDENWNVKIADFGFARIKEENAIMTR-----CGTPCWTAPEIIRNDIYDEKVDVFS 1580 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 FG+ ++E+LT + +++T + R P CP E Sbjct 1581 FGIVMWEVLTCKEPF---------------IGANFMKITMDILEDVRPKIPQDCPEEFAK 1625 Query 1147 LMKNCWETEASFRPTFENLIPILKTV 1172 LM+ CW +++ RPT +++I +L Sbjct 1626 LMRKCWHAKSTKRPTMDDVIIVLAKF 1651 Score = 240 bits (612), Expect = 4e-63, Method: Composition-based stats. Identities = 79/295 (27%), Positives = 120/295 (41%), Gaps = 35/295 (12%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG--PQHRSGWKQE 947 L+ LG G FG+V + G VAVK + D +K E Sbjct 779 WEIDFHELELGEQLGTGAFGEVHKGTWR------GTEVAVKMISPDKTITKDIERNFKDE 832 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFA 1004 + ++ TL H +++ + + +VME++ LGSL D L I A + A Sbjct 833 VRVMTTLRHPNVVLFMAASTKP--PKMCIVMEFMALGSLHDLLKNELIPDIPFALKVKIA 890 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 Q +GM +LH+ HRDL + N+LLD VK+ DFGL K + E Sbjct 891 YQASKGMHFLHSSGITHRDLKSLNLLLDIKWNVKVSDFGLTKFKSDVKSINP--EKFAGT 948 Query 1065 VFWYAPECLKEYK--FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 + W APE L E + Y SDV+SFG+ ++EL+T G Sbjct 949 IQWTAPEILSEDREVDYILSDVYSFGIIMWELITRDQPYF--------------GMSPAA 994 Query 1123 RLTELLERGERLPRPD----KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 ++ R D + E L+ +CW + + RPTF ++ L + Sbjct 995 IAVSVIRDNYRPVISDQLRSEVAPEYIELLTSCWHFDPTIRPTFLEIMTRLSNLM 1049 Score = 231 bits (590), Expect = 2e-60, Method: Composition-based stats. Identities = 70/359 (19%), Positives = 123/359 (34%), Gaps = 65/359 (18%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 +D E+ LG G V++G R V Sbjct 777 DDWEIDFHELELGEQLGTGAFGEVHKGTWRG--------------------------TEV 810 Query 640 VLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +K++ P DI F + +M+ + H ++ + P+ +V E++ G L Sbjct 811 AVKMISPDKTITKDIERNFKDEVRVMTTLRHPNVVLFMAASTKPPKMCIVMEFMALGSLH 870 Query 697 VWLRRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 L+ E +P A K+ +A Q + + +L + + H ++ N+LL + Sbjct 871 DLLKNELIPDIPFALKVKIAYQASKGMHFLHSSGITHRDLKSLNLLLD-------IKWNV 923 Query 756 KLSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K+SD G+ +++ E+ I W APE L D + FG + E+ Sbjct 924 KVSDFGLTKFKSDVKSINPEKFAGTIQWTAPEILSEDREVDYILSDVYSFGIIMWELITR 983 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSC-------PQLATLTSQCLTYEPTQRPSFRTIL 863 + P SP+ R + P S P+ L + C ++PT RP+F I+ Sbjct 984 -DQPYFGMSPAAIAVSVIRDNYRPVISDQLRSEVAPEYIELLTSCWHFDPTIRPTFLEIM 1042 Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922 L+ L FGKV + + T+ Sbjct 1043 TRLSNL---------------MGDSGMTGMSSSSSNSSKFDYNSFGKVQQFAINRTDPD 1086 Score = 226 bits (576), Expect = 9e-59, Method: Composition-based stats. Identities = 53/298 (18%), Positives = 107/298 (36%), Gaps = 42/298 (14%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 R L + L ++ EI +G G+ VY G+ + Sbjct 1382 RYLTSAGLCSWVINYDEIKMGEQIGLGSYGVVYRGKWKN--------------------- 1420 Query 632 DRGQELRVVLKVLDPSHHDIALAF--YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 + V +K D E + + ++ H ++ + G ++ P +VTEY Sbjct 1421 -----VDVAIKKFIKQKIDENHLLGIREEIAFLKKLHHPNIITMVGASLKKPNICIVTEY 1475 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGL 747 + G L +R + K+ + +A +SYL + ++H ++ NIL+ Sbjct 1476 MAKGNLRDAMRTCTPKLEWHQKIKILVNIAKGISYLHSFDPPIIHRDIKPSNILIDE--- 1532 Query 748 AEGTSPFIKLSDPGVGLGALSRE--ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + +K++D G R W APE + +D + FG + Sbjct 1533 ----NWNVKIADFGFARIKEENAIMTRCGTPCWTAPEIIRNDI--YDEKVDVFSFGIVMW 1586 Query 806 EICFDGEAPLQSRSPSEKEHFYQR-QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 E+ E + + + + ++P+ + A L +C + T+RP+ + Sbjct 1587 EVLTCKEPFIGANFMKITMDILEDVRPKIPQDCPEEFAKLMRKCWHAKSTKRPTMDDV 1644 >sp|Q78DX7|ROS1_MOUSE Proto-oncogene tyrosine-protein kinase ROS OS=Mus musculus OX=10090 GN=Ros1 PE=1 SV=1 Length=2340 Score = 267 bits (682), Expect = 1e-71, Method: Composition-based stats. Identities = 95/291 (33%), Positives = 139/291 (48%), Gaps = 32/291 (11%) Query 907 HFGKVSLYC-YDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG 964 FG+V D G+GE VAVK LK Q + + +E ++ H +I+K G Sbjct 1948 AFGEVYEGTAIDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLG 2007 Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYLPRH--------SIGLAQLLLFAQQICEGMAYLHA 1016 C + +++E + G L YL + S+ L L+ I +G YL Sbjct 2008 VCLLGEPQ--YIILELMEGGDLLSYLRKARGTTFHGPSLTLLDLVELCVDISKGCVYLEQ 2065 Query 1017 QHYIHRDLAARNVLL-----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 H+IHRDLAARN L+ + R+VKIGDFGLA+ + + ++YYR R +G PV W APE Sbjct 2066 MHFIHRDLAARNCLVSVKDYTSPRVVKIGDFGLAREIYK-NDYYRKRGEGLLPVRWMAPE 2124 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 L + F SDVWSFG+ ++E+LT L + L + ++ G Sbjct 2125 NLMDGIFTSQSDVWSFGILVWEILT--------------LGHQPYPAHSNLDVLNYVQAG 2170 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182 RL P CP ++++LM CW E RPTF N+ L+ + Sbjct 2171 GRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHNIQNQLQLFRNVFLNNVSH 2221 Score = 248 bits (633), Expect = 2e-65, Method: Composition-based stats. Identities = 76/298 (26%), Positives = 123/298 (41%), Gaps = 39/298 (13%) Query 599 TRTNVYEGR-LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFY 656 VYEG + + G G E++V +K L D F Sbjct 1948 AFGEVYEGTAIDILGVGSG-------------------EIKVAVKTLKKGSTDQEKIEFL 1988 Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG------HVPMAW 710 + A LMS+ +H ++ GVC+ G ++ E +E G L +LR+ RG + + Sbjct 1989 KEAHLMSKFNHPNILKQLGVCLLGEPQYIILELMEGGDLLSYLRKARGTTFHGPSLTLLD 2048 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + + ++ YLE + +H ++ RN L++ + +K+ D G+ + Sbjct 2049 LVELCVDISKGCVYLEQMHFIHRDLAARNCLVSVK--DYTSPRVVKIGDFGLAREIYKND 2106 Query 771 ERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 +R + W+APE L G ++ D W FG + EI G P + S + Sbjct 2107 YYRKRGEGLLPVRWMAPENLMDGI--FTSQSDVWSFGILVWEILTLGHQPYPAHSNLDVL 2164 Query 825 HFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880 ++ Q RL P +CP L L SQC EP QRP+F I L + L +V Sbjct 2165 NYVQAGGRLEPPRNCPDDLWNLMSQCWAQEPDQRPTFHNIQNQLQLFRNVFLNNVSHC 2222 >sp|F4JPX3|PBL20_ARATH Probable serine/threonine-protein kinase PBL20 OS=Arabidopsis thaliana OX=3702 GN=PBL20 PE=3 SV=1 Length=388 Score = 247 bits (631), Expect = 2e-71, Method: Composition-based stats. Identities = 93/386 (24%), Positives = 146/386 (38%), Gaps = 21/386 (5%) Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT--LTSQCLTYEPTQRPSFRTI 862 F + P SR EKE R + S P+L T T P PS +I Sbjct 3 CLFLFMSKKPK-SRGNMEKEKKNIRGREFLQKSAPELTTRKTTLSFNLPTPRSLPSPTSI 61 Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD----P 918 + N + + +GEG FG V + Sbjct 62 KD-----LYTDREQNQNQNLRVFSFKELSDATCEFSRKLKIGEGGFGSVYKATINNPTVG 116 Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978 + + VAVK L H+ W E+ L + H ++++ G C + E+ LV Sbjct 117 DSHSSPLTVAVKKLNRQSLQGHKQ-WLAEVHFLGVVNHPNVVRLLGYCSEDRER--LLVY 173 Query 979 EYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035 E + SL D+L ++ Q L +G+AYLH I+RD + NVLL+ + Sbjct 174 ELMSNRSLEDHLFTLRTLTLSWKQRLEIMLGAAQGLAYLHEIQVIYRDFKSSNVLLNEEF 233 Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 K+ DFGLA+ PEG + V + APE + DV+SFGV LYE++ Sbjct 234 HPKLSDFGLAREGPEGDNTH-VTTARVGTDGYAAPEYVITGHLKTHCDVYSFGVVLYEII 292 Query 1096 THCDSSQ--SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 T + + P + L + + + R +++ P V L +C Sbjct 293 TGRRTLERMKPLAEQKLLEWVKKYPINSKRFKMIVDSKLCNKYPIAMVRRVAKLADHCVN 352 Query 1154 TEASFRPTFENLIPILKTVHEKYQGQ 1179 RPT ++ L + E+ + Sbjct 353 KIDKERPTMAFVVESLTNIIEESNSE 378 Score = 220 bits (560), Expect = 5e-62, Method: Composition-based stats. Identities = 65/340 (19%), Positives = 116/340 (34%), Gaps = 39/340 (11%) Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRC-CLPQPGETSNLII 563 F ++ +E ++ L + R F+L LP P +L Sbjct 7 FMSKKPKSRGNMEKEKKNIRGREFLQKSAPELTTRKTTLSFNLPTPRSLPSPTSIKDLYT 66 Query 564 MRGARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 R + NL SF + E ++ +G+G +VY+ + GD + Sbjct 67 DREQNQNQ---NLRVFSFKELSDATCEFSRKLKIGEGGFGSVYKATINNPTVGDSHSSPL 123 Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 V +K L+ + + V+H ++ + G C Sbjct 124 ----------------TVAVKKLNRQSLQGHKQWLAEVHFLGVVNHPNVVRLLGYCSEDR 167 Query 682 ENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNI 740 E ++V E + + L+ L R + ++ + A L+YL +++ + N+ Sbjct 168 ERLLVYELMSNRSLEDHLFTLRTLTLSWKQRLEIMLGAAQGLAYLHEIQVIYRDFKSSNV 227 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTA 794 LL KLSD G+ + RV + APE + G L T Sbjct 228 LLNEE-------FHPKLSDFGLAREGPEGDNTHVTTARVGTDGYAAPEYVITG--HLKTH 278 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834 D + FG L EI G L+ P ++ + + P Sbjct 279 CDVYSFGVVLYEII-TGRRTLERMKPLAEQKLLEWVKKYP 317 >sp|Q3EDL4|Y1154_ARATH Probable serine/threonine-protein kinase At1g01540 OS=Arabidopsis thaliana OX=3702 GN=At1g01540 PE=1 SV=2 Length=472 Score = 250 bits (638), Expect = 2e-71, Method: Composition-based stats. Identities = 68/282 (24%), Positives = 123/282 (44%), Gaps = 19/282 (7%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 + +GEG +G V G VAVK L + G Q +K E++++ + H+ Sbjct 155 CEENVIGEGGYGIVYRGIL-----TDGTKVAVKNLLNNRG-QAEKEFKVEVEVIGRVRHK 208 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQICEGMA 1012 ++++ G C + + LV ++V G+L ++ + + + +G+A Sbjct 209 NLVRLLGYCVEGAYR--MLVYDFVDNGNLEQWIHGDVGDVSPLTWDIRMNIILGMAKGLA 266 Query 1013 YLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH +HRD+ + N+LLD K+ DFGLAK + Y R + A Sbjct 267 YLHEGLEPKVVHRDIKSSNILLDRQWNAKVSDFGLAKLLGSESSYVTTR--VMGTFGYVA 324 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE SD++SFG+ + E++T + S P L+ + + R E++ Sbjct 325 PEYACTGMLNEKSDIYSFGILIMEIITGRNPVDYSRPQGETNLVDWLKSMVGNRRSEEVV 384 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + P K V + C + +A+ RP ++I +L+ Sbjct 385 DPKIPEPPSSKALKRVLLVALRCVDPDANKRPKMGHIIHMLE 426 Score = 218 bits (555), Expect = 2e-60, Method: Composition-based stats. Identities = 62/312 (20%), Positives = 113/312 (36%), Gaps = 64/312 (21%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 + + + +G+G VY G L +V +K Sbjct 148 EAATNGLCEENVIGEGGYGIVYRGILTDG-------------------------TKVAVK 182 Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 L + F ++ +V H +L + G CV G ++V ++V++G L+ W+ + Sbjct 183 NLLNNRGQAEKEFKVEVEVIGRVRHKNLVRLLGYCVEGAYRMLVYDFVDNGNLEQWIHGD 242 Query 703 RGHV-PMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 G V P+ W +M + +A L+YL +VH ++ NILL R K Sbjct 243 VGDVSPLTWDIRMNIILGMAKGLAYLHEGLEPKVVHRDIKSSNILLDRQ-------WNAK 295 Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 +SD G+ + + ++APE G L+ D + FG ++EI G Sbjct 296 VSDFGLAKLLGSESSYVTTRVMGTFGYVAPEYACTGM--LNEKSDIYSFGILIMEII-TG 352 Query 812 EAPLQSRSPSEKEHFYQR------QHRLPEPSCPQLAT------------LTSQCLTYEP 853 P+ P + + R E P++ + +C+ + Sbjct 353 RNPVDYSRPQGETNLVDWLKSMVGNRRSEEVVDPKIPEPPSSKALKRVLLVALRCVDPDA 412 Query 854 TQRPSFRTILRD 865 +RP I+ Sbjct 413 NKRPKMGHIIHM 424 >sp|Q93YN1|CRPK1_ARATH Cold-responsive protein kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CRPK1 PE=1 SV=1 Length=390 Score = 247 bits (631), Expect = 2e-71, Method: Composition-based stats. Identities = 72/297 (24%), Positives = 124/297 (42%), Gaps = 21/297 (7%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 +GEG FG V C G++ A+K L A+ Q + Sbjct 29 YKYREIRQATDDFSAENKIGEGGFGSVYKGCLK-----DGKLAAIKVLSAE-SRQGVKEF 82 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSIGL 997 EI+++ + HE+++K GCC + + LV ++ SL L Sbjct 83 LTEINVISEIQHENLVKLYGCCVEGNHR--ILVYNFLENNSLDKTLLAGGYTRSGIQFDW 140 Query 998 AQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + + +G+A+LH + H IHRD+ A N+LLD KI DFGLA+ +P + Sbjct 141 SSRANICVGVAKGLAFLHEEVRPHIIHRDIKASNILLDKYLSPKISDFGLARLMPPNMTH 200 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIG 1113 R G + + APE + +D++SFGV L E+++ + + PT++ L+ Sbjct 201 VSTRVAG--TIGYLAPEYAVRGQLTRKADIYSFGVLLMEIVSGRSNKNTRLPTEYQYLLE 258 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 A L +L++ G + C + C + RP+ ++ +L Sbjct 259 RAWELYERNELVDLVDSGLNGVFDAEEACRYLKIGLLCTQDSPKLRPSMSTVVRLLT 315 Score = 217 bits (553), Expect = 6e-61, Method: Composition-based stats. Identities = 61/291 (21%), Positives = 112/291 (38%), Gaps = 52/291 (18%) Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 N+ + + + + + +G+G +VY+G L+ Sbjct 25 NVKIYKYREIRQATDDFSAENKIGEGGFGSVYKGCLKDGK-------------------- 64 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 +KVL F +++S++ H +L ++G CV G I+V ++E+ Sbjct 65 -----LAAIKVLSAESRQGVKEFLTEINVISEIQHENLVKLYGCCVEGNHRILVYNFLEN 119 Query 693 GPLDVWLR-----RERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744 LD L R + + + +A L++L + +++H ++ NILL + Sbjct 120 NSLDKTLLAGGYTRSGIQFDWSSRANICVGVAKGLAFLHEEVRPHIIHRDIKASNILLDK 179 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWG 799 K+SD G+ V I +LAPE G L+ D + Sbjct 180 YLSP-------KISDFGLARLMPPNMTHVSTRVAGTIGYLAPEYAVRG--QLTRKADIYS 230 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLT 850 FG L+EI G + +R P+E ++ +R L E + +L L L Sbjct 231 FGVLLMEIVS-GRSNKNTRLPTEYQYLLERAWELYERN--ELVDLVDSGLN 278 >sp|Q9LZU4|CRK4_ARATH Cysteine-rich receptor-like protein kinase 4 OS=Arabidopsis thaliana OX=3702 GN=CRK4 PE=2 SV=1 Length=676 Score = 256 bits (653), Expect = 2e-71, Method: Composition-based stats. Identities = 76/285 (27%), Positives = 121/285 (42%), Gaps = 19/285 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 + LG+G FG+V + +G VAVK L G R + E+ ++ L H Sbjct 351 FCETNKLGQGGFGEVYKGIF-----PSGVQVAVKRLSKTSGQGERE-FANEVIVVAKLQH 404 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMA 1012 ++++ G C ++ E+ LV E+VP SL ++ + + + I G+ Sbjct 405 RNLVRLLGFCLERDER--ILVYEFVPNKSLDYFIFDSTMQSLLDWTRRYKIIGGIARGIL 462 Query 1013 YLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH IHRDL A N+LL +D KI DFG+A+ R + + Sbjct 463 YLHQDSRLTIIHRDLKAGNILLGDDMNAKIADFGMARIFGMDQTEANTRR-IVGTYGYMS 521 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTE 1126 PE +F SDV+SFGV + E+++ +S Q T L+ + E Sbjct 522 PEYAMYGQFSMKSDVYSFGVLVLEIISGKKNSNVYQMDGTSAGNLVTYTWRLWSNGSPLE 581 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 L++ R H+ C + EA RPT ++ +L T Sbjct 582 LVDPSFRDNYRINEVSRCIHIALLCVQEEAEDRPTMSAIVQMLTT 626 Score = 230 bits (586), Expect = 2e-62, Method: Composition-based stats. Identities = 57/325 (18%), Positives = 110/325 (34%), Gaps = 66/325 (20%) Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 T Q F ++ + + + LGQG VY+G Sbjct 333 TAGSLQFDFKAIEAATNKFCETNKLGQGGFGEVYKGI----------------------- 369 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 ++V +K L + F +++++ H +L + G C+ E I+V E+V Sbjct 370 --FPSGVQVAVKRLSKTSGQGEREFANEVIVVAKLQHRNLVRLLGFCLERDERILVYEFV 427 Query 691 EHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745 + LD ++ + W + + +A + YL + ++H ++ NILL Sbjct 428 PNKSLDYFIFDSTMQSLLDWTRRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNILL--- 484 Query 746 GLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 G K++D G+ + V +++PE G S D + Sbjct 485 ----GDDMNAKIADFGMARIFGMDQTEANTRRIVGTYGYMSPEYAMYG--QFSMKSDVYS 538 Query 800 FGATLLEICFDGE-APLQSRSPSEKEHFYQRQHRLPEPSCP------------------Q 840 FG +LEI + + + + + RL P + Sbjct 539 FGVLVLEIISGKKNSNVYQMDGTSAGNLVTYTWRLWSNGSPLELVDPSFRDNYRINEVSR 598 Query 841 LATLTSQCLTYEPTQRPSFRTILRD 865 + C+ E RP+ I++ Sbjct 599 CIHIALLCVQEEAEDRPTMSAIVQM 623 >sp|P80192|M3K9_HUMAN Mitogen-activated protein kinase kinase kinase 9 OS=Homo sapiens OX=9606 GN=MAP3K9 PE=1 SV=3 Length=1104 Score = 263 bits (673), Expect = 2e-71, Method: Composition-based stats. Identities = 93/293 (32%), Positives = 135/293 (46%), Gaps = 41/293 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP---QHRSGWKQEIDILRTLYHEHI 959 +G G FGKV + G+ VAVKA + D Q +QE + L H +I Sbjct 150 IGIGGFGKVYRAFWI------GDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPNI 203 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 I +G C E +L LVME+ G L L I L+ +A QI GM YLH + Sbjct 204 IALRGVCLK--EPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIARGMNYLHDEAI 261 Query 1018 -HYIHRDLAARNVLL-------D-NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 IHRDL + N+L+ D +++++KI DFGLA+ + + W Sbjct 262 VPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLAR-----EWHRTTKMSAAGTYAWM 316 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 APE ++ F SDVWS+GV L+ELLT P + ++ + +A G + Sbjct 317 APEVIRASMFSKGSDVWSYGVLLWELLTG-----EVPFRGIDGLAVAYG---------VA 362 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 LP P CP LM++CW + RP+F N++ L T+ E + P Sbjct 363 MNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNILDQLTTIEESGFFEMP 415 Score = 236 bits (602), Expect = 2e-62, Method: Composition-based stats. Identities = 89/483 (18%), Positives = 168/483 (35%), Gaps = 75/483 (16%) Query 513 AFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPR 572 + G + ++ L +GD+ + + SN + R A +S Sbjct 62 EYEAAGEDELTLRLGDVVEVLSKDSQVSGDEGWWTGQLNQRVGIFPSNYVTPRSAFSSRC 121 Query 573 TLN------LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 + +D E+T +G G VY + Sbjct 122 QPGGEDPSCYPPIQLLEIDFAELTLEEIIGIGGFGKVYRAFWIGD--------------- 166 Query 627 LVPGRDRGQELRVVLKVL----DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 V +K D + A L + + H ++ + GVC++ P Sbjct 167 -----------EVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPN 215 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRN 739 +V E+ GPL+ L +R +P + A Q+A ++YL ++ ++H ++ N Sbjct 216 LCLVMEFARGGPLNRVLSGKR--IPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSN 273 Query 740 IL-LARLGLAEGTSPFIKLSDPGVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMD 796 IL L ++ + ++ +K++D G+ ++ W+APE + A+ S D Sbjct 274 ILILQKVENGDLSNKILKITDFGLAREWHRTTKMSAAGTYAWMAPEVIR--ASMFSKGSD 331 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEP 853 W +G L E+ GE P + + + +P A L C +P Sbjct 332 VWSYGVLLWELL-TGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDP 390 Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 RPSF IL LT ++ ++ + + + ++R Sbjct 391 HSRPSFTNILDQLTTIEESGFFEMPKDSFHCLQDNWKHEIQEMFDQLRA----------- 439 Query 914 YCYDPTNDGTGEM----VAV--KALKADCGPQHRSGWKQEIDIL-RTLYHEHIIKYKGCC 966 T E A+ K + + + ++EIDIL R L +II C Sbjct 440 ---KEKELRTWEEELTRAALQQKNQEELLRRREQELAEREIDILEREL---NII-IHQLC 492 Query 967 EDQ 969 +++ Sbjct 493 QEK 495 >sp|Q63132|ROS1_RAT Proto-oncogene tyrosine-protein kinase ROS OS=Rattus norvegicus OX=10116 GN=Ros1 PE=2 SV=1 Length=2338 Score = 266 bits (681), Expect = 2e-71, Method: Composition-based stats. Identities = 96/283 (34%), Positives = 138/283 (49%), Gaps = 32/283 (11%) Query 907 HFGKVSLYC-YDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG 964 FG+V D G+GE VAVK LK Q + + +E ++ H +I+K G Sbjct 1947 AFGEVYEGTAVDILGRGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLG 2006 Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------IGLAQLLLFAQQICEGMAYLHA 1016 C + +++E + G L YL + + LA L+ I +G YL Sbjct 2007 VCLLSEPQ--YIILELMEGGDLLSYLRKARGTTLSGPLLTLADLVELCVDISKGCVYLEQ 2064 Query 1017 QHYIHRDLAARNVLL-----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 H+IHRDLAARN L+ + R+VKIGDFGLA+ + + H+YYR R +G PV W APE Sbjct 2065 MHFIHRDLAARNCLVSVKDYTSPRVVKIGDFGLAREIYK-HDYYRKRGEGLLPVRWMAPE 2123 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 L + F SDVWSFG+ ++E+LT L + L + ++ G Sbjct 2124 NLMDGIFTSQSDVWSFGILVWEILT--------------LGHQPYPAHSNLDVLNYVQAG 2169 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 RL P CP ++++LM CW E RPTF N+ L+ Sbjct 2170 GRLEPPRNCPDDLWNLMFRCWAQEPDQRPTFYNIQDQLQLFRN 2212 Score = 246 bits (627), Expect = 7e-65, Method: Composition-based stats. Identities = 75/297 (25%), Positives = 123/297 (41%), Gaps = 37/297 (12%) Query 599 TRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYE 657 VYEG + GR G E++V +K L D F + Sbjct 1947 AFGEVYEGT-----------------AVDILGRGSG-EIKVAVKTLKKGSTDQEKIEFLK 1988 Query 658 TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH------VPMAWK 711 A LMS+ +H ++ GVC+ ++ E +E G L +LR+ RG + +A Sbjct 1989 EAHLMSKFNHPNILKQLGVCLLSEPQYIILELMEGGDLLSYLRKARGTTLSGPLLTLADL 2048 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771 + + ++ YLE + +H ++ RN L++ + +K+ D G+ + Sbjct 2049 VELCVDISKGCVYLEQMHFIHRDLAARNCLVSVK--DYTSPRVVKIGDFGLAREIYKHDY 2106 Query 772 RVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 +R + W+APE L G ++ D W FG + EI G P + S + + Sbjct 2107 YRKRGEGLLPVRWMAPENLMDGI--FTSQSDVWSFGILVWEILTLGHQPYPAHSNLDVLN 2164 Query 826 FYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880 + Q RL P +CP L L +C EP QRP+F I L + +L +V Sbjct 2165 YVQAGGRLEPPRNCPDDLWNLMFRCWAQEPDQRPTFYNIQDQLQLFRNVSLNNVSHC 2221 >sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens OX=9606 GN=TNK2 PE=1 SV=3 Length=1038 Score = 262 bits (670), Expect = 2e-71, Method: Composition-based stats. Identities = 106/272 (39%), Positives = 151/272 (56%), Gaps = 21/272 (8%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG V +D + T VAVK LK D P+ + +E++ + +L H ++ Sbjct 131 KLGDGSFGVVRRGEWDAPSGKT-VSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNL 189 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQ 1017 I+ G +++V E PLGSL D L +H L L +A Q+ EGM YL ++ Sbjct 190 IRLYGVVLTP---PMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESK 246 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +IHRDLAARN+LL LVKIGDFGL +A+P+ ++Y ++E P W APE LK Sbjct 247 RFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRT 306 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F +ASD W FGVTL+E+ T+ IG+ Q+ L ++ + GERLPRP Sbjct 307 FSHASDTWMFGVTLWEMFTYGQEP---------WIGLNGSQI----LHKIDKEGERLPRP 353 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + CP ++Y++M CW + RPTF L L Sbjct 354 EDCPQDIYNVMVQCWAHKPEDRPTFVALRDFL 385 Score = 233 bits (593), Expect = 1e-61, Method: Composition-based stats. Identities = 87/353 (25%), Positives = 136/353 (39%), Gaps = 54/353 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + +K++ L LG G+ V G G+ + V +K Sbjct 121 IGEKDLRLLEKLGDGSFGVVRRGEW---------------------DAPSGKTVSVAVKC 159 Query 644 LDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 L P S + F + M + H +L ++GV + P MVTE G L LR Sbjct 160 LKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLT-PPMKMVTELAPLGSLLDRLR 218 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + +GH + A Q+A + YLE+K +H ++ RN+LLA T +K+ D Sbjct 219 KHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLA-------TRDLVKIGDF 271 Query 761 GVGLG-------ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ + +E R W APE L + S A D W FG TL E+ G+ Sbjct 272 GLMRALPQNDDHYVMQEHRKVPFAWCAPESLKT--RTFSHASDTWMFGVTLWEMFTYGQE 329 Query 814 PLQSRSPSEKEH-FYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P + S+ H + RLP P CPQ + + QC ++P RP+F + L Q Sbjct 330 PWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQ 389 Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923 P ++ + ++ G+ Y + N T Sbjct 390 PTDMRALQDFEEPDKLHIQMNDVITVIE----------GRAENYWWRGQNTRT 432 >sp|Q1RMT8|IRAK4_BOVIN Interleukin-1 receptor-associated kinase 4 OS=Bos taurus OX=9913 GN=IRAK4 PE=2 SV=1 Length=461 Score = 249 bits (636), Expect = 2e-71, Method: Composition-based stats. Identities = 77/312 (25%), Positives = 128/312 (41%), Gaps = 20/312 (6%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 L+ + + + +GEG FG V VA Sbjct 159 LEFSDTRFHSFSFFELKDVTNNFDERPISVGGNKMGEGGFGVVYKGYV------NNRTVA 212 Query 929 VKALKAD---CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 VK L A + + + QEI ++ HE++++ G D + L LV Y+P GS Sbjct 213 VKKLAAMVDISTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDD--LCLVYVYMPNGS 270 Query 986 LRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 L D L + AQ G++YLH H+IHRD+ + N+LLD D KI D Sbjct 271 LLDRLSCLDGTPPLSWNMRCKIAQGAANGLSYLHENHHIHRDIKSANILLDEDFTAKISD 330 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLA+A + + + + APE L+ SD++SFGV L E++T + Sbjct 331 FGLARASEKFAQTVMTSRIVGTTA-YMAPEALRGE-ITPKSDIYSFGVVLLEIITGLPAV 388 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE-VYHLMKNCWETEASFRP 1160 L L + + + + ++R ++ D E +Y + C + + RP Sbjct 389 DEHREPQLLLDIKEEIEDEEKTIEDYVDR--KMNDIDSTSIETMYSVASQCLHEKKNKRP 446 Query 1161 TFENLIPILKTV 1172 + + +L+ + Sbjct 447 DIKKVQQLLEEM 458 Score = 223 bits (567), Expect = 4e-62, Method: Composition-based stats. Identities = 70/352 (20%), Positives = 128/352 (36%), Gaps = 76/352 (22%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQ-------------LSHLGQGTRTNVY 604 N ++ + +L S FH E+ + +G+G VY Sbjct 143 EQNYVLPDSSSPENTSLEFSDTRFHSFSFFELKDVTNNFDERPISVGGNKMGEGGFGVVY 202 Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL----DPSHHDIALAFYETAS 660 +G + V +K L D S ++ F + Sbjct 203 KGYVNNR--------------------------TVAVKKLAAMVDISTEELKQQFDQEIK 236 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQL 718 +M++ H +L + G G + +V Y+ +G L L G P++W + +AQ Sbjct 237 VMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWNMRCKIAQGA 296 Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA------LSREER 772 A+ LSYL + +H ++ NILL K+SD G+ + + Sbjct 297 ANGLSYLHENHHIHRDIKSANILLDE-------DFTAKISDFGLARASEKFAQTVMTSRI 349 Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS----------- 821 V ++APE L G ++ D + FG LLEI A + R P Sbjct 350 VGTTAYMAPEALRG---EITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIED 406 Query 822 ----EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 +++ ++ + + S + ++ SQCL + +RP + + + L + Sbjct 407 EEKTIEDYVDRKMNDIDSTSIETMYSVASQCLHEKKNKRPDIKKVQQLLEEM 458 >sp|Q15303|ERBB4_HUMAN Receptor tyrosine-protein kinase erbB-4 OS=Homo sapiens OX=9606 GN=ERBB4 PE=1 SV=1 Length=1308 Score = 265 bits (676), Expect = 3e-71, Method: Composition-based stats. Identities = 98/272 (36%), Positives = 140/272 (51%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + VA+K L GP+ + E I+ ++ H H+++ Sbjct 724 LGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRL 783 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C +QLV + +P G L +Y+ H IG LL + QI +GM YL + + Sbjct 784 LGVCLSPT---IQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV 840 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ + VKI DFGLA+ + EG E + G P+ W A EC+ KF + Sbjct 841 HRDLAARNVLVKSPNHVKITDFGLARLL-EGDEKEYNADGGKMPIKWMALECIHYRKFTH 899 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T G + + +LLE+GERLP+P C Sbjct 900 QSDVWSYGVTIWELMTFG--------------GKPYDGIPTREIPDLLEKGERLPQPPIC 945 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW +A RP F+ L + Sbjct 946 TIDVYMVMVKCWMIDADSRPKFKELAAEFSRM 977 Score = 241 bits (615), Expect = 1e-63, Method: Composition-based stats. Identities = 67/338 (20%), Positives = 131/338 (39%), Gaps = 39/338 (12%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P +Q + + E+ ++ LG G VY+G EG Sbjct 699 TPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETV-------------- 744 Query 630 GRDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ V +K+L+ + + F + A +M+ + H HL + GVC+ P +VT+ Sbjct 745 ------KIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCL-SPTIQLVTQ 797 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + HG L ++ + ++ + Q+A + YLE + LVH ++ RN+L+ Sbjct 798 LMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPN-- 855 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 +K++D G+ + + I W+A EC+ + D W +G Sbjct 856 -----HVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIH--YRKFTHQSDVWSYGV 908 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860 T+ E+ G P E ++ RLP+P + + +C + RP F+ Sbjct 909 TIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFK 968 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898 + + +R+ ++ D K + Sbjct 969 ELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQN 1006 >sp|Q9YI66|TYRO3_DANRE Tyrosine-protein kinase receptor TYRO3 OS=Danio rerio OX=7955 GN=tyro3 PE=2 SV=1 Length=874 Score = 259 bits (662), Expect = 3e-71, Method: Composition-based stats. Identities = 94/337 (28%), Positives = 150/337 (45%), Gaps = 28/337 (8%) Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVS 912 P + R+ R L L + + + +R L R LG+G FG V Sbjct 453 PVSFTAARSFNRQFPELPESTLDSLGINSDLKAKLQDVLIFERLLTLGRMLGKGEFGSVR 512 Query 913 LYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 N+ +G+ VAVK LK D +E ++ +H ++I+ G + Sbjct 513 EAFLKSENN-SGQKVAVKVLKTDINSSSDIEQCLKEAAYMKDFHHPNVIQLIGVSLHRRA 571 Query 972 KS----LQLVMEYVPLGSLRDYLPRHSIGLAQ-------LLLFAQQICEGMAYLHAQHYI 1020 + +++ ++ G L +L +G L+ F I GM YL ++ I Sbjct 572 QQRLPIPMVILPFMKHGDLHTFLLMSRLGDEPFTVSQQILIQFMLDIARGMEYLSNKNII 631 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARN +L+ + V + DFGL+K + G +YYR PV W A E L + + Sbjct 632 HRDLAARNCMLNENMSVCVADFGLSKKIYSG-DYYRQGSVSKLPVKWIALESLADNVYTT 690 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVW+FGVT++E++T + + E L +GERL +P C Sbjct 691 QSDVWAFGVTMWEIMTRGQ--------------TPYPGVENSEIYEYLIKGERLKQPPDC 736 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 P ++Y +M +CW RP+F++LI L+ + K Sbjct 737 PADIYEIMHSCWSPVPKCRPSFQHLIDQLELLWAKLN 773 Score = 217 bits (552), Expect = 5e-57, Method: Composition-based stats. Identities = 63/300 (21%), Positives = 118/300 (39%), Gaps = 47/300 (16%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 +T LG+G +V E L+ E + GQ++ V + D + Sbjct 497 LTLGRMLGKGEFGSVREAFLKSEN-------------------NSGQKVAVKVLKTDINS 537 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEYVEHGPLDVWLRRE 702 + A+ M H ++ + GV + P +++ +++HG L +L Sbjct 538 SSDIEQCLKEAAYMKDFHHPNVIQLIGVSLHRRAQQRLPIPMVILPFMKHGDLHTFLLMS 597 Query 703 R---GHVPMAWKMVV--AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 R ++ ++++ +A + YL NKN++H ++ RN +L + + + Sbjct 598 RLGDEPFTVSQQILIQFMLDIARGMEYLSNKNIIHRDLAARNCMLNE-------NMSVCV 650 Query 758 SDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 +D G+ S + + + W+A E L +T D W FG T+ EI G Sbjct 651 ADFGLSKKIYSGDYYRQGSVSKLPVKWIALESLADNV--YTTQSDVWAFGVTMWEIMTRG 708 Query 812 EAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + P SE + + RL P + + C + P RPSF+ ++ L L Sbjct 709 QTPYPGVENSEIYEYLIKGERLKQPPDCPADIYEIMHSCWSPVPKCRPSFQHLIDQLELL 768 >sp|P57097|MERTK_RAT Tyrosine-protein kinase Mer OS=Rattus norvegicus OX=10116 GN=Mertk PE=2 SV=1 Length=994 Score = 261 bits (667), Expect = 3e-71, Method: Composition-based stats. Identities = 90/283 (32%), Positives = 136/283 (48%), Gaps = 27/283 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG FG V DGT + VAVK +K D + + E ++ H ++I+ Sbjct 588 LGEGEFGSVMEGNLK-QEDGTSQKVAVKTMKLDNFSLREIEEFLSEAACMKDFNHPNVIR 646 Query 962 YKGCCED---QGEKSLQLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEGM 1011 G C + QG +++ ++ G L +L SI L LL F I +GM Sbjct 647 LLGVCIELSSQGIPKPMVILPFMKYGDLHTFLLYSRIESVPKSIPLQTLLKFMVDIAQGM 706 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 YL +++++HRDLAARN +L +D V + DFGL+K + G +YYR PV W A E Sbjct 707 EYLSSRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQGRIAKMPVKWIAIE 765 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 L + + SDVW+FGVT++E+ T + + + L G Sbjct 766 SLADRVYTSKSDVWAFGVTMWEIATRG--------------MTPYPGVQNHEMYDYLLHG 811 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 RL +P+ C ++Y +M +CW + RPTF L L+ + E Sbjct 812 HRLKQPEDCLDDLYEIMYSCWSADPLDRPTFSVLRLQLEKLSE 854 Score = 234 bits (596), Expect = 4e-62, Method: Composition-based stats. Identities = 67/313 (21%), Positives = 119/313 (38%), Gaps = 50/313 (16%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 ++L VD+ + LG+G +V EG L+ E G Sbjct 570 NKLEDVVVDRNLLILGKVLGEGEFGSVMEGNLKQED---------------------GTS 608 Query 637 LRVVLKV--LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-----GPENIMVTEY 689 +V +K LD F A+ M +H ++ + GVC+ P+ +++ + Sbjct 609 QKVAVKTMKLDNFSLREIEEFLSEAACMKDFNHPNVIRLLGVCIELSSQGIPKPMVILPF 668 Query 690 VEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 +++G L +L R +P+ + +A + YL ++N +H ++ RN +L Sbjct 669 MKYGDLHTFLLYSRIESVPKSIPLQTLLKFMVDIAQGMEYLSSRNFLHRDLAARNCML-- 726 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKW 798 + ++D G+ S + + W+A E L ++ D W Sbjct 727 -----RDDMTVCVADFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRV--YTSKSDVW 779 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 FG T+ EI G P E + HRL PE L + C + +P R Sbjct 780 AFGVTMWEIATRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDDLYEIMYSCWSADPLDR 839 Query 857 PSFRTILRDLTRL 869 P+F + L +L Sbjct 840 PTFSVLRLQLEKL 852 >sp|O54967|ACK1_MOUSE Activated CDC42 kinase 1 OS=Mus musculus OX=10090 GN=Tnk2 PE=1 SV=2 Length=1055 Score = 261 bits (668), Expect = 5e-71, Method: Composition-based stats. Identities = 107/272 (39%), Positives = 151/272 (56%), Gaps = 21/272 (8%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG V +D T VAVK LK D P+ + +E++ + +L H ++ Sbjct 131 KLGDGSFGVVRRGEWDAPAGKT-VSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNL 189 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQ 1017 I+ G +++V E PLGSL D L +H L L +A Q+ EGMAYL ++ Sbjct 190 IRLYGVVLTL---PMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMAYLESK 246 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +IHRDLAARN+LL LVKIGDFGL +A+P+ ++Y ++E P W APE LK Sbjct 247 RFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRT 306 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F +ASD W FGVTL+E+ T+ IG+ Q+ L ++ + GERLPRP Sbjct 307 FSHASDTWMFGVTLWEMFTYGQEP---------WIGLNGSQI----LHKIDKEGERLPRP 353 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + CP ++Y++M CW + RPTF L L Sbjct 354 EDCPQDIYNVMVQCWAHKPEDRPTFVALRDFL 385 Score = 231 bits (590), Expect = 3e-61, Method: Composition-based stats. Identities = 87/353 (25%), Positives = 137/353 (39%), Gaps = 54/353 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + +K++ L LG G+ V G G+ + V +K Sbjct 121 IGEKDLRLLEKLGDGSFGVVRRGEWDAPA---------------------GKTVSVAVKC 159 Query 644 LDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 L P S + F + M + H +L ++GV + P MVTE G L LR Sbjct 160 LKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTLPMK-MVTELAPLGSLLDRLR 218 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + +GH + A Q+A ++YLE+K +H ++ RN+LLA T +K+ D Sbjct 219 KHQGHFLLGTLSRYAVQVAEGMAYLESKRFIHRDLAARNLLLA-------TRDLVKIGDF 271 Query 761 GVGLG-------ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ + +E R W APE L + S A D W FG TL E+ G+ Sbjct 272 GLMRALPQNDDHYVMQEHRKVPFAWCAPESLKT--RTFSHASDTWMFGVTLWEMFTYGQE 329 Query 814 PLQSRSPSEKEH-FYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P + S+ H + RLP P CPQ + + QC ++P RP+F + L Q Sbjct 330 PWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQ 389 Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923 P ++ + ++ G+ Y + N T Sbjct 390 PTDMRALQDFEEPDKLHIQMNDVITVIE----------GRAENYWWRGQNTRT 432 >sp|P11273|ERBB_AVIEU Tyrosine-protein kinase transforming protein erbB OS=Avian erythroblastosis virus (strain ts167) OX=103898 GN=V-ERBB PE=3 SV=1 Length=540 Score = 251 bits (640), Expect = 5e-71, Method: Composition-based stats. Identities = 92/272 (34%), Positives = 136/272 (50%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + VA+K L+ P+ E ++ ++ + H+ + Sbjct 138 LGFGAFGTVYKGLWIPEGEKVTIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRL 197 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C +QL+ + +P G L DY+ H IG LL + QI +GM YL +H + Sbjct 198 LGICLTST---VQLITQLMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERHMV 254 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ + VKI DFGLAK + + Y E G P+ W A E + + + Sbjct 255 HRDLAARNVLVKTPQHVKITDFGLAKQLGADEKEYHA-EGGKVPIKWMALESILHRIYTH 313 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + ++ +LE+GERLP+P C Sbjct 314 QSDVWSYGVTVWELMTFGSK--------------PYDGIPASEISSVLEKGERLPQPPIC 359 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW ++A RP F LI + Sbjct 360 TIDVYMIMVKCWMSDADSRPKFRELIAEFSKM 391 Score = 221 bits (564), Expect = 7e-61, Method: Composition-based stats. Identities = 67/345 (19%), Positives = 136/345 (39%), Gaps = 39/345 (11%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P +Q + + E ++ LG G VY+G EG Sbjct 113 TPSGEAPNQAHLRILKETEFKKVKVLGFGAFGTVYKGLWIPEGEKVT------------- 159 Query 630 GRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 + V +K L + + A +M+ V + H+ + G+C+ ++T+ Sbjct 160 -------IPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQ-LITQ 211 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + +G L ++R + ++ + + Q+A ++YLE +++VH ++ RN+L+ Sbjct 212 LMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERHMVHRDLAARNVLV------ 265 Query 749 EGTSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGA 802 T +K++D G+ LGA +E E I W+A E + + D W +G Sbjct 266 -KTPQHVKITDFGLAKQLGADEKEYHAEGGKVPIKWMALESILHRI--YTHQSDVWSYGV 322 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860 T+ E+ G P SE ++ RLP+P + + +C + RP FR Sbjct 323 TVWELMTFGSKPYDGIPASEISSVLEKGERLPQPPICTIDVYMIMVKCWMSDADSRPKFR 382 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 ++ + +++ ++ + K Y + + Sbjct 383 ELIAEFSKMARDPPRYLVIQGDERMHLPSPTDSKFYRTLMEEEDM 427 >sp|Q9SYS7|CRK39_ARATH Putative cysteine-rich receptor-like protein kinase 39 OS=Arabidopsis thaliana OX=3702 GN=CRK39 PE=3 SV=1 Length=659 Score = 254 bits (648), Expect = 6e-71, Method: Composition-based stats. Identities = 73/276 (26%), Positives = 116/276 (42%), Gaps = 20/276 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG+G FG V G+ VAVK L G +K E+ +L L H +++ Sbjct 357 NTLGQGGFGTVYKGTL-----LNGQEVAVKRLTKGSGQGDIE-FKNEVSLLTRLQHRNLV 410 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016 K G C + E+ LV E+VP SL ++ R + + I G+ YLH Sbjct 411 KLLGFCNEGDEQ--ILVYEFVPNSSLDHFIFDDEKRSLLTWEMRYRIIEGIARGLLYLHE 468 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRDL A N+LLD + K+ DFG A+ + + APE L Sbjct 469 DSQLKIIHRDLKASNILLDAEMNPKVADFGTARLFDSDETRAETKRIA-GTRGYMAPEYL 527 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + SDV+SFGV L E+++ ++ + E + + V E++ Sbjct 528 NHGQISAKSDVYSFGVMLLEMISGERNN----SFEGEGLAAFAWKRWVEGKPEIIIDPFL 583 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + +P ++ + C + + RPT ++I L Sbjct 584 IEKPRNEIIKLIQIGLLCVQENPTKRPTMSSVIIWL 619 Score = 246 bits (627), Expect = 3e-68, Method: Composition-based stats. Identities = 71/338 (21%), Positives = 116/338 (34%), Gaps = 60/338 (18%) Query 554 QPGETSNLIIMRGARASPRTLNL---SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRV 610 + E+ N I + A S L E + + LGQG VY+G L Sbjct 315 RRKESYNKINVGSAEYSDSDGQFMLRFDLGMVLAATDEFSSENTLGQGGFGTVYKGTLLN 374 Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670 V +K L + F SL++++ H +L Sbjct 375 GQ-------------------------EVAVKRLTKGSGQGDIEFKNEVSLLTRLQHRNL 409 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK 728 + G C G E I+V E+V + LD ++ + + W + + + +A L YL Sbjct 410 VKLLGFCNEGDEQILVYEFVPNSSLDHFIFDDEKRSLLTWEMRYRIIEGIARGLLYLHED 469 Query 729 ---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWL 779 ++H ++ NILL K++D G S E R ++ Sbjct 470 SQLKIIHRDLKASNILLD-------AEMNPKVADFGTARLFDSDETRAETKRIAGTRGYM 522 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGE----------APLQSRSPSEKEHFYQR 829 APE L G +S D + FG LLE+ A R K Sbjct 523 APEYLNHG--QISAKSDVYSFGVMLLEMISGERNNSFEGEGLAAFAWKRWVEGKPEIIID 580 Query 830 QHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + P +L + C+ PT+RP+ +++ Sbjct 581 PFLIEKPRNEIIKLIQIGLLCVQENPTKRPTMSSVIIW 618 >sp|Q93105|INSR_AEDAE Insulin-like receptor OS=Aedes aegypti OX=7159 GN=InR PE=2 SV=2 Length=1393 Score = 264 bits (674), Expect = 7e-71, Method: Composition-based stats. Identities = 91/321 (28%), Positives = 152/321 (47%), Gaps = 31/321 (10%) Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPTND 921 R +++ D + ++ ++ +LG+G FG V + Sbjct 991 YRYMSKQIRMYPEVNPDYAGVQYKVDDWEVERNHIIQLEELGQGSFGMVYKGILTQLRGE 1050 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 + A+K + + + + E +++ H+++ G QG+ +L ++ME + Sbjct 1051 KCNQPCAIKTVNESATAREKDSFLLEASVMKQFNTHHVVRLLGVV-SQGDPTL-VIMELM 1108 Query 982 PLGSLRDYLPRHSIG-------------LAQLLLFAQQICEGMAYLHAQHYIHRDLAARN 1028 G L+ YL RH L Q++ A +I +GMAYL A+ ++HRDLAARN Sbjct 1109 ANGDLKSYLRRHRPDYENGEDPSPQPPTLRQIIQMAIEIADGMAYLSAKKFVHRDLAARN 1168 Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 ++ +D VKIGDFG+ + + E +YYR G PV W APE LK+ F +SDV+S+G Sbjct 1169 CMVADDMTVKIGDFGMTRDIYE-TDYYRKGTKGFLPVRWMAPESLKDGIFSSSSDVFSYG 1227 Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148 V L+E+ T L +T ++ + G + RP+ CP +Y+LM Sbjct 1228 VVLWEMAT--------------LASQPYQGLTNDQVLRYVIDGGVMERPENCPDNLYNLM 1273 Query 1149 KNCWETEASFRPTFENLIPIL 1169 + CW+ + RPTF +I L Sbjct 1274 RRCWQHRPTARPTFMEIISEL 1294 Score = 244 bits (622), Expect = 1e-64, Method: Composition-based stats. Identities = 68/305 (22%), Positives = 118/305 (39%), Gaps = 48/305 (16%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 ++ V++ I QL LGQG+ VY+G L R Sbjct 1014 KVDDWEVERNHIIQLEELGQGSFGMVYKGIL-------------------TQLRGEKCNQ 1054 Query 638 RVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +K ++ S F AS+M Q + H+ + GV +G +++ E + +G L Sbjct 1055 PCAIKTVNESATAREKDSFLLEASVMKQFNTHHVVRLLGVVSQGDPTLVIMELMANGDLK 1114 Query 697 VWLRRERG-----------HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 +LRR R + + +A ++A ++YL K VH ++ RN ++A Sbjct 1115 SYLRRHRPDYENGEDPSPQPPTLRQIIQMAIEIADGMAYLSAKKFVHRDLAARNCMVA-- 1172 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWG 799 +K+ D G+ + + + W+APE L G S++ D + Sbjct 1173 -----DDMTVKIGDFGMTRDIYETDYYRKGTKGFLPVRWMAPESLKDGI--FSSSSDVFS 1225 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRP 857 +G L E+ P Q + + + + PE L L +C + PT RP Sbjct 1226 YGVVLWEMATLASQPYQGLTNDQVLRYVIDGGVMERPENCPDNLYNLMRRCWQHRPTARP 1285 Query 858 SFRTI 862 +F I Sbjct 1286 TFMEI 1290 >sp|O64771|Y1148_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61480 OS=Arabidopsis thaliana OX=3702 GN=At1g61480 PE=2 SV=2 Length=809 Score = 257 bits (656), Expect = 7e-71, Method: Composition-based stats. Identities = 79/307 (26%), Positives = 125/307 (41%), Gaps = 17/307 (6%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 + LG+G FG V G+ +AVK L + G Q + Sbjct 483 FFEMNTIQTATDNFSLSNKLGQGGFGSVYKGKLQ-----DGKEIAVKRLSSSSG-QGKEE 536 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ 999 + EI ++ L H+++++ GCC + E+ LV E++ SL +L R I + Sbjct 537 FMNEIVLISKLQHKNLVRILGCCIEGEER--LLVYEFLLNKSLDTFLFDSRKRLEIDWPK 594 Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 + I G+ YLH IHRDL N+LLD KI DFGLA+ + +G EY Sbjct 595 RFNIIEGIARGLHYLHRDSCLRVIHRDLKVSNILLDEKMNPKISDFGLAR-MYQGTEYQD 653 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIA 1115 + + APE F SD++SFGV L E++T S S + L+ A Sbjct 654 NTRRVAGTLGYMAPEYAWTGMFSEKSDIYSFGVILLEIITGEKISRFSYGRQGKTLLAYA 713 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 +LL++ + C + + + RP L+ +L T + Sbjct 714 WESWCESGGIDLLDKDVADSCHPLEVERCVQIGLLCVQHQPADRPNTMELLSMLTTTSDL 773 Query 1176 YQGQAPS 1182 + P+ Sbjct 774 TSPKQPT 780 Score = 235 bits (599), Expect = 3e-63, Method: Composition-based stats. Identities = 54/247 (22%), Positives = 95/247 (38%), Gaps = 45/247 (18%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L +++ + + + LGQG +VY+G+L+ Sbjct 481 LKFFEMNTIQTATDNFSLSNKLGQGGFGSVYKGKLQDGK--------------------- 519 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + +K L S F L+S++ H +L + G C+ G E ++V E++ + Sbjct 520 ----EIAVKRLSSSSGQGKEEFMNEIVLISKLQHKNLVRILGCCIEGEERLLVYEFLLNK 575 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748 LD +L R + + W + + + +A L YL ++H ++ NILL Sbjct 576 SLDTFLFDSRKRLEIDWPKRFNIIEGIARGLHYLHRDSCLRVIHRDLKVSNILLDEK--- 632 Query 749 EGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGA 802 K+SD G+ E + + ++APE G S D + FG Sbjct 633 ----MNPKISDFGLARMYQGTEYQDNTRRVAGTLGYMAPEYAWTGM--FSEKSDIYSFGV 686 Query 803 TLLEICF 809 LLEI Sbjct 687 ILLEIIT 693 >sp|Q04912|RON_HUMAN Macrophage-stimulating protein receptor OS=Homo sapiens OX=9606 GN=MST1R PE=1 SV=3 Length=1400 Score = 263 bits (673), Expect = 9e-71, Method: Composition-based stats. Identities = 93/303 (31%), Positives = 142/303 (47%), Gaps = 27/303 (9%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCY--DPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 + R +G+GHFG V Y N A+K+L Q + +E Sbjct 1076 PHERVVTHSDRVIGKGHFGVVYHGEYIDQAQNRI---QCAIKSLSRITEMQQVEAFLREG 1132 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQ 1006 ++R L H +++ G E +++ Y+ G L ++ P+ + + L+ F Q Sbjct 1133 LLMRGLNHPNVLALIGIML-PPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQ 1191 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-YRVREDGDSPV 1065 + GM YL Q ++HRDLAARN +LD VK+ DFGLA+ + + Y + PV Sbjct 1192 VARGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPV 1251 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 W A E L+ Y+F SDVWSFGV L+ELLT + LT Sbjct 1252 KWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAP--------------PYRHIDPFDLT 1297 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG----QAP 1181 L +G RLP+P+ CP +Y +M+ CWE + + RPTF L+ ++ + G Q P Sbjct 1298 HFLAQGRRLPQPEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLP 1357 Query 1182 SVF 1184 + + Sbjct 1358 ATY 1360 Score = 229 bits (583), Expect = 9e-60, Method: Composition-based stats. Identities = 68/318 (21%), Positives = 121/318 (38%), Gaps = 44/318 (14%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDI 651 +G+G VY G + ++ +K L + Sbjct 1086 RVIGKGHFGVVYHGEYIDQAQNR---------------------IQCAIKSLSRITEMQQ 1124 Query 652 ALAFYETASLMSQVSHTHLAFVHGVCV--RGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 AF LM ++H ++ + G+ + G +++ Y+ HG L ++R + + + Sbjct 1125 VEAFLREGLLMRGLNHPNVLALIGIMLPPEGLPHVL-LPYMCHGDLLQFIRSPQRNPTVK 1183 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 + Q+A + YL + VH ++ RN +L S +K++D G+ L R Sbjct 1184 DLISFGLQVARGMEYLAEQKFVHRDLAARNCMLDE-------SFTVKVADFGLARDILDR 1236 Query 770 EERVE--------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 E + W+A E L +T D W FG L E+ G P + P Sbjct 1237 EYYSVQQHRHARLPVKWMALESLQT--YRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPF 1294 Query 822 EKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 + HF + RLP+P CP L + QC +P RP+FR ++ ++ ++ L D Sbjct 1295 DLTHFLAQGRRLPQPEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYV 1354 Query 880 VNPDSPASDPTVFHKRYL 897 P + + Sbjct 1355 QLPATYMNLGPSTSHEMN 1372 >sp|Q9FG33|LRKS5_ARATH Probable L-type lectin-domain containing receptor kinase S.5 OS=Arabidopsis thaliana OX=3702 GN=LECRKS5 PE=2 SV=1 Length=652 Score = 253 bits (646), Expect = 9e-71, Method: Composition-based stats. Identities = 66/283 (23%), Positives = 120/283 (42%), Gaps = 22/283 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG+G FG V + + +AVK + ++ Q + + EI + L H +++ Sbjct 334 NKLGQGGFGMVFKGKWQGRD------IAVKRV-SEKSHQGKQEFIAEITTIGNLNHRNLV 386 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLH 1015 K G C ++ E LV EY+P GSL YL R ++ + + + YLH Sbjct 387 KLLGWCYERKE--YLLVYEYMPNGSLDKYLFLEDKSRSNLTWETRKNIITGLSQALEYLH 444 Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 + +HRD+ A NV+LD+D K+GDFGLA+ + + + ++ + APE Sbjct 445 NGCEKRILHRDIKASNVMLDSDFNAKLGDFGLARMIQQSEMTHHSTKEIAGTPGYMAPET 504 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE-----LIGIAQGQMTVLRLTEL 1127 + +DV++FGV + E+++ S ++ +T+ Sbjct 505 FLNGRATVETDVYAFGVLMLEVVSGKKPSYVLVKDNQNNYNNSIVNWLWELYRNGTITDA 564 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + G + V L C + RP+ + ++ +L Sbjct 565 ADPGMGNLFDKEEMKSVLLLGLACCHPNPNQRPSMKTVLKVLT 607 Score = 227 bits (579), Expect = 7e-62, Method: Composition-based stats. Identities = 65/329 (20%), Positives = 120/329 (36%), Gaps = 74/329 (22%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 A+P+ L +L + + LGQG V++G+ Sbjct 313 ANPQKFKLREL---KRATGNFGAENKLGQGGFGMVFKGKW-------------------- 349 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 Q + +K + H F + + ++H +L + G C E ++V E Sbjct 350 ------QGRDIAVKRVSEKSHQGKQEFIAEITTIGNLNHRNLVKLLGWCYERKEYLLVYE 403 Query 689 YVEHGPLDVWLR---RERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILL 742 Y+ +G LD +L + R ++ + + L+ AL YL N K ++H ++ N++L Sbjct 404 YMPNGSLDKYLFLEDKSRSNLTWETRKNIITGLSQALEYLHNGCEKRILHRDIKASNVML 463 Query 743 ARLGLAEGTSPFIKLSDPGVGL-------GALSREERVERIPWLAPECLPGGANSLSTAM 795 + KL D G+ S +E ++APE G ++ T Sbjct 464 D-------SDFNAKLGDFGLARMIQQSEMTHHSTKEIAGTPGYMAPETFLNGRATVET-- 514 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFY----------QRQHRLPEPSCPQLATLT 845 D + FG +LE+ G+ P + ++ R + + + P + L Sbjct 515 DVYAFGVLMLEVVS-GKKPSYVLVKDNQNNYNNSIVNWLWELYRNGTITDAADPGMGNLF 573 Query 846 SQ------------CLTYEPTQRPSFRTI 862 + C P QRPS +T+ Sbjct 574 DKEEMKSVLLLGLACCHPNPNQRPSMKTV 602 >sp|Q5U2X5|ACK1_RAT Activated CDC42 kinase 1 OS=Rattus norvegicus OX=10116 GN=Tnk2 PE=2 SV=1 Length=1040 Score = 260 bits (665), Expect = 9e-71, Method: Composition-based stats. Identities = 106/272 (39%), Positives = 149/272 (55%), Gaps = 21/272 (8%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG V +D T VAVK LK D P+ + +E++ + +L H ++ Sbjct 131 KLGDGSFGVVRRGEWDAPAGKT-VSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNL 189 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQ 1017 I+ G +++V E PLGSL D L +H L L +A Q+ EGM YL ++ Sbjct 190 IRLYGVVLTP---PMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESK 246 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +IHRDLAARN+LL LVKIGDFGL +A+P+ +Y ++E P W APE LK Sbjct 247 RFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDGHYVMQEHRKVPFAWCAPESLKTRT 306 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F +ASD W FGVTL+E+ T+ IG+ Q+ L ++ + GERLPRP Sbjct 307 FSHASDTWMFGVTLWEMFTYGQEP---------WIGLNGSQI----LHKIDKEGERLPRP 353 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + CP ++Y++M CW + RPTF L L Sbjct 354 EDCPQDIYNVMVQCWAHKPEDRPTFVALRDFL 385 Score = 233 bits (594), Expect = 1e-61, Method: Composition-based stats. Identities = 87/353 (25%), Positives = 136/353 (39%), Gaps = 54/353 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + +K++ L LG G+ V G G+ + V +K Sbjct 121 IGEKDLRLLEKLGDGSFGVVRRGEWDAPA---------------------GKTVSVAVKC 159 Query 644 LDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 L P S + F + M + H +L ++GV + P MVTE G L LR Sbjct 160 LKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLT-PPMKMVTELAPLGSLLDRLR 218 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + +GH + A Q+A + YLE+K +H ++ RN+LLA T +K+ D Sbjct 219 KHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLA-------TRDLVKIGDF 271 Query 761 GVGLG-------ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ + +E R W APE L + S A D W FG TL E+ G+ Sbjct 272 GLMRALPQNDGHYVMQEHRKVPFAWCAPESLKT--RTFSHASDTWMFGVTLWEMFTYGQE 329 Query 814 PLQSRSPSEKEH-FYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P + S+ H + RLP P CPQ + + QC ++P RP+F + L Q Sbjct 330 PWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQ 389 Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923 P ++ + ++ G+ Y + N T Sbjct 390 PTDMRALQDFEEPDKLHIQMNDVITVIE----------GRAENYWWRGQNTRT 432 >sp|Q8RWW0|ALE2_ARATH Receptor-like serine/threonine-protein kinase ALE2 OS=Arabidopsis thaliana OX=3702 GN=ALE2 PE=1 SV=1 Length=744 Score = 255 bits (652), Expect = 1e-70, Method: Composition-based stats. Identities = 89/348 (26%), Positives = 135/348 (39%), Gaps = 22/348 (6%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 P F + R + ++ + R LGEG FG Sbjct 302 NKRPGAGSMFSSSARSSGSDSLMSSMATCALSVKTFTLSELEKATDRFSAKRVLGEGGFG 361 Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 +V + G VAVK L D + R + E+++L L+H +++K G C + Sbjct 362 RVYQG-----SMEDGTEVAVKLLTRDNQNRDRE-FIAEVEMLSRLHHRNLVKLIGICIEG 415 Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAA 1026 + L+ E V GS+ +L ++ L A G+AYLH IHRD A Sbjct 416 RTR--CLIYELVHNGSVESHLHEGTLDWDARLKIALGAARGLAYLHEDSNPRVIHRDFKA 473 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 NVLL++D K+ DFGLA+ EG ++ R + APE SDV+S Sbjct 474 SNVLLEDDFTPKVSDFGLAREATEGSQHISTR--VMGTFGYVAPEYAMTGHLLVKSDVYS 531 Query 1087 FGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLR-LTELLERGERLPRPDKCPCEV 1144 +GV L ELLT S P+ L+ A+ + L +L++ +V Sbjct 532 YGVVLLELLTGRRPVDMSQPSGEENLVTWARPLLANREGLEQLVDPALAGTYNFDDMAKV 591 Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHE-------KYQGQAPSVFS 1185 + C E S RP ++ LK ++ Y Q S Sbjct 592 AAIASMCVHQEVSHRPFMGEVVQALKLIYNDADETCGDYCSQKDSSVP 639 Score = 223 bits (569), Expect = 6e-60, Method: Composition-based stats. Identities = 63/338 (19%), Positives = 116/338 (34%), Gaps = 67/338 (20%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 S +T LS+L + LG+G VY+G + Sbjct 333 SVKTFTLSELEK---ATDRFSAKRVLGEGGFGRVYQGSMEDG------------------ 371 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 V +K+L + + F ++S++ H +L + G+C+ G ++ E Sbjct 372 -------TEVAVKLLTRDNQNRDREFIAEVEMLSRLHHRNLVKLIGICIEGRTRCLIYEL 424 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLG 746 V +G ++ L G + ++ +A A L+YL ++H + N+LL Sbjct 425 VHNGSVESHLH--EGTLDWDARLKIALGAARGLAYLHEDSNPRVIHRDFKASNVLL---- 478 Query 747 LAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFG 801 K+SD G+ A + + ++APE G L D + +G Sbjct 479 ---EDDFTPKVSDFGLAREATEGSQHISTRVMGTFGYVAPEYAMTG--HLLVKSDVYSYG 533 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-------------------PEPSCPQLA 842 LLE+ G P+ PS +E+ L ++A Sbjct 534 VVLLELL-TGRRPVDMSQPSGEENLVTWARPLLANREGLEQLVDPALAGTYNFDDMAKVA 592 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880 + S C+ E + RP +++ L + Sbjct 593 AIASMCVHQEVSHRPFMGEVVQALKLIYNDADETCGDY 630 >sp|P08922|ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3 Length=2347 Score = 264 bits (675), Expect = 1e-70, Method: Composition-based stats. Identities = 96/287 (33%), Positives = 139/287 (48%), Gaps = 32/287 (11%) Query 903 LGEGHFGKVSLYC-YDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG G FG+V D G+GE VAVK LK Q + + +E ++ H +I+ Sbjct 1951 LGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNIL 2010 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI--------GLAQLLLFAQQICEGMA 1012 K G C + +++E + G L YL + + L L+ I +G Sbjct 2011 KQLGVCLLNEPQ--YIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCV 2068 Query 1013 YLHAQHYIHRDLAARNVLL-----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 YL H+IHRDLAARN L+ + R+VKIGDFGLA+ + + ++YYR R +G PV W Sbjct 2069 YLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYK-NDYYRKRGEGLLPVRW 2127 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE L + F SDVWSFG+ ++E+LT L + L + Sbjct 2128 MAPESLMDGIFTTQSDVWSFGILIWEILT--------------LGHQPYPAHSNLDVLNY 2173 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 ++ G RL P CP ++++LM CW E RPTF + L+ Sbjct 2174 VQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRN 2220 Score = 250 bits (638), Expect = 3e-66, Method: Composition-based stats. Identities = 78/317 (25%), Positives = 129/317 (41%), Gaps = 37/317 (12%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 ++++T LG G VYEG D L G E++V +K L Sbjct 1941 PREKLTLRLLLGSGAFGEVYEGT---------------AVDILGVGSG---EIKVAVKTL 1982 Query 645 DPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 D F + A LMS+ +H ++ GVC+ ++ E +E G L +LR+ R Sbjct 1983 KKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKAR 2042 Query 704 ------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + + + + ++ YLE + +H ++ RN L++ + +K+ Sbjct 2043 MATFYGPLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVK--DYTSPRIVKI 2100 Query 758 SDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 D G+ + +R + W+APE L G +T D W FG + EI G Sbjct 2101 GDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGI--FTTQSDVWSFGILIWEILTLG 2158 Query 812 EAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 P + S + ++ Q RL P +CP L L +QC EP QRP+F I L Sbjct 2159 HQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLF 2218 Query 870 QPHNLADVLTVNPDSPA 886 + L + ++ Sbjct 2219 RNFFLNSIYKSRDEANN 2235 >sp|Q9FM85|PBL16_ARATH Probable serine/threonine-protein kinase PBL16 OS=Arabidopsis thaliana OX=3702 GN=PBL16 PE=1 SV=1 Length=408 Score = 245 bits (626), Expect = 1e-70, Method: Composition-based stats. Identities = 82/290 (28%), Positives = 125/290 (43%), Gaps = 16/290 (6%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-----VAVKALKADCGPQHRSGWKQEIDI 950 ++ R LG G FG V + G E+ VAVK D Q W E+ Sbjct 75 NFRQDRVLGGGGFGSVYKGFIK-EDLGDQEVPEPLPVAVKVHDGDNSFQGHREWLAEVIF 133 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQI 1007 L L H +++K G C + + L+ EY+ GS+ + L + A + A Sbjct 134 LGQLSHPNLVKLIGYCCEDNHR--VLIYEYMARGSVENNLFSRVLLPLSWAIRMKIAFGA 191 Query 1008 CEGMAYLHA--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 +G+A+LH + I+RD N+LLD D K+ DFGLAK P G + + V Sbjct 192 AKGLAFLHEAKKPVIYRDFKTSNILLDMDYNAKLSDFGLAKDGPVGDKSH-VSTRIMGTY 250 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQM-TVLR 1123 + APE + SDV+SFGV L ELLT S +S PT+ LI A + + Sbjct 251 GYAAPEYIMTGHLTPGSDVYSFGVVLLELLTGRKSLDKSRPTREQNLIDWALPLLKEKKK 310 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + +++ P K + L +C RP +++ L+ + Sbjct 311 VLNIVDPKMNCEYPVKAVQKAAMLAYHCLNRNPKARPLMRDIVDSLEPLQ 360 Score = 220 bits (560), Expect = 1e-61, Method: Composition-based stats. Identities = 74/345 (21%), Positives = 128/345 (37%), Gaps = 56/345 (16%) Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P + +R A+ + + + Q LG G +VY+G ++ + Sbjct 43 PSNPKEVEDLRRDSAANPLIAFTYEELKNI-TSNFRQDRVLGGGGFGSVYKGFIKED--- 98 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFV 673 + D++ P L V +KV D + + + Q+SH +L + Sbjct 99 ------LGDQEVPEP-------LPVAVKVHDGDNSFQGHREWLAEVIFLGQLSHPNLVKL 145 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN--KN 729 G C +++ EY+ G ++ L R +P++W +M +A A L++L K Sbjct 146 IGYCCEDNHRVLIYEYMARGSVENNLF-SRVLLPLSWAIRMKIAFGAAKGLAFLHEAKKP 204 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPEC 783 +++ + NILL KLSD G+ ++ + + APE Sbjct 205 VIYRDFKTSNILLD-------MDYNAKLSDFGLAKDGPVGDKSHVSTRIMGTYGYAAPEY 257 Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL---------- 833 + G L+ D + FG LLE+ ++ +SR E+ L Sbjct 258 IMTG--HLTPGSDVYSFGVVLLELLTGRKSLDKSRPTREQNLIDWALPLLKEKKKVLNIV 315 Query 834 -PEPSCPQ-------LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P+ +C A L CL P RP R I+ L LQ Sbjct 316 DPKMNCEYPVKAVQKAAMLAYHCLNRNPKARPLMRDIVDSLEPLQ 360 >sp|Q75JK0|ZAK1_DICDI Dual specificity protein kinase zakA OS=Dictyostelium discoideum OX=44689 GN=zakA PE=1 SV=1 Length=781 Score = 256 bits (654), Expect = 1e-70, Method: Composition-based stats. Identities = 92/469 (20%), Positives = 160/469 (34%), Gaps = 92/469 (20%) Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832 + ++APE + D W G T++E+ S+K + Sbjct 235 IGTFNYMAPEV--KRNYRATRKSDVWSLGCTIIEMA--------GGDLSQKLN---GIPI 281 Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH-------------------- 872 +P+ L + CL +P +R +L + Sbjct 282 IPDHLSDTLKDFLNHCLVIDPKKRSYMEELLSHKLIVHIIGPNKSKNYGVEPKFKDDDDF 341 Query 873 -------------NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919 + P + + K + G G+FG V + T Sbjct 342 EEIENEKDNYLSSRFPAKFAPQYEKPKWEIEFEELEFDKDDSEGGAGNFGDVKKGLLNET 401 Query 920 NDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHIIKYKGCCEDQGEK--SLQ 975 VA+K +K + E+ IL L H +I+++ C GEK + Sbjct 402 ------EVAIKFVKKAHCEAITVCDTFYHEVLILSNLRHPNIVQFMAACIKYGEKETNHC 455 Query 976 LVMEYVPLGSLRDYLPRHSIGLAQ----LLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031 +V E++ G+L +L + L + I +G+ YLH QH IHRDL + NVLL Sbjct 456 IVSEWMSGGNLTQFLMNNHKVLENNPHLRVKLLTDIAKGILYLHKQHIIHRDLTSNNVLL 515 Query 1032 D-------------NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 D N+ K+ DFGL+ E + + + APE L Sbjct 516 DFKREILPNQLYGSNEFTAKVCDFGLSSNQSESKKL------RGGSIHYMAPENLNGSPI 569 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SD++SFG+ ++++ ++ + + ++ R P Sbjct 570 NEKSDIYSFGLLVWQMFSYAPP------------NTIYSPKEMASMVSDPKQNYRPQIPF 617 Query 1139 KCPCEVYHLMKNCWETEASFRP-TFENLIPILKTVHEKYQGQAPSVFSV 1186 P + L+ CW+ RP F +I LK + Y + +V + Sbjct 618 NVPLKFKELITQCWDRNPLNRPKDFSIIIEKLKEIGLTYNRSSSNVSPI 666 Score = 199 bits (507), Expect = 1e-51, Method: Composition-based stats. Identities = 55/305 (18%), Positives = 111/305 (36%), Gaps = 53/305 (17%) Query 582 HRVDQKEITQLS---HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 ++ +E+ G G +V +G L E Sbjct 369 WEIEFEELEFDKDDSEGGAGNFGDVKKGLL--------------------------NETE 402 Query 639 VVLKVLDPSHHDIA---LAFYETASLMSQVSHTHLAFVHGVCVRGPE----NIMVTEYVE 691 V +K + +H + FY ++S + H ++ C++ E + +V+E++ Sbjct 403 VAIKFVKKAHCEAITVCDTFYHEVLILSNLRHPNIVQFMAACIKYGEKETNHCIVSEWMS 462 Query 692 HGPLDVWLRRERGHVPMA--WKMVVAQQLASALSYLENKNLVHGNVCGRNILLA------ 743 G L +L + ++ + +A + YL ++++H ++ N+LL Sbjct 463 GGNLTQFLMNNHKVLENNPHLRVKLLTDIAKGILYLHKQHIIHRDLTSNNVLLDFKREIL 522 Query 744 RLGLAEGTSPFIKLSDPGVGLG-ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 L K+ D G+ + S++ R I ++APE L G + ++ D + FG Sbjct 523 PNQLYGSNEFTAKVCDFGLSSNQSESKKLRGGSIHYMAPENLNG--SPINEKSDIYSFGL 580 Query 803 TLLEICFDGEAPLQSRSPSEKEHF-----YQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857 + ++ P SP E + ++P + L +QC P RP Sbjct 581 LVWQMFSYA-PPNTIYSPKEMASMVSDPKQNYRPQIPFNVPLKFKELITQCWDRNPLNRP 639 Query 858 SFRTI 862 +I Sbjct 640 KDFSI 644 Score = 114 bits (286), Expect = 1e-24, Method: Composition-based stats. Identities = 37/164 (23%), Positives = 75/164 (46%), Gaps = 13/164 (8%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM--VAVKALKADCGPQHRSGWKQ 946 +K ++I +GEG +G+V ++ VA+K + D + Sbjct 1 MHYHNKDDWEEISFIGEGQYGRVIKCRKKNGFILNEQVDYVAIKIISKDKFK------RN 54 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLF 1003 E DIL + +I +Y + + + + MEY+ +L + L + ++++ Sbjct 55 ETDILEKIRLFNIPRYY--SHAEDDNFIYIYMEYIEGENLANILKTKKQGRFKESRIISM 112 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 + E +++LH H IHRD+ N++LD ++ +K+ DFG + Sbjct 113 IADLVETLSFLHKHHVIHRDIKTANLVLDKNKNLKLIDFGASTI 156 Score = 95.5 bits (236), Expect = 1e-18, Method: Composition-based stats. Identities = 25/184 (14%), Positives = 66/184 (36%), Gaps = 31/184 (17%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 H ++ + ++S +G+G V + R + + + V + Sbjct 2 HYHNKDDWEEISFIGEGQYGRVIKCRKKNGFILNEQVDY------------------VAI 43 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR- 700 K++ ++ ++ ++ + + EY+E L L+ Sbjct 44 KIISKDKFK-----RNETDILEKIRLFNIPRYYSHAEDDNFIYIYMEYIEGENLANILKT 98 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 +++G + + + L LS+L +++H ++ N++L + + +KL D Sbjct 99 KKQGRFKESRIISMIADLVETLSFLHKHHVIHRDIKTANLVLDK-------NKNLKLIDF 151 Query 761 GVGL 764 G Sbjct 152 GAST 155 Score = 69.3 bits (168), Expect = 2e-10, Method: Composition-based stats. Identities = 27/125 (22%), Positives = 42/125 (34%), Gaps = 29/125 (23%) Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 G++ + E +Y + + APE + Y+ SDVWS G T+ E+ D SQ Sbjct 218 GISTYLNE--QYKQSSFAIIGTFNYMAPEVKRNYRATRKSDVWSLGCTIIEMA-GGDLSQ 274 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 L GI PD + + +C + R Sbjct 275 K-------LNGI-------------------PIIPDHLSDTLKDFLNHCLVIDPKKRSYM 308 Query 1163 ENLIP 1167 E L+ Sbjct 309 EELLS 313 >sp|Q12866|MERTK_HUMAN Tyrosine-protein kinase Mer OS=Homo sapiens OX=9606 GN=MERTK PE=1 SV=2 Length=999 Score = 260 bits (664), Expect = 1e-70, Method: Composition-based stats. Identities = 93/284 (33%), Positives = 136/284 (48%), Gaps = 29/284 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ-HRSGWKQEIDILRTLYHEHIIK 961 LGEG FG V DGT VAVK +K D Q + E ++ H ++I+ Sbjct 593 LGEGEFGSVMEGNLK-QEDGTSLKVAVKTMKLDNSSQREIEEFLSEAACMKDFSHPNVIR 651 Query 962 YKGCCEDQGEKSL---QLVMEYVPLGSLRDYL--------PRHSIGLAQLLLFAQQICEG 1010 G C + + + +++ ++ G L YL P+H I L LL F I G Sbjct 652 LLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKH-IPLQTLLKFMVDIALG 710 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 M YL ++++HRDLAARN +L +D V + DFGL+K + G +YYR PV W A Sbjct 711 MEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQGRIAKMPVKWIAI 769 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E L + + SDVW+FGVT++E+ T + + + L Sbjct 770 ESLADRVYTSKSDVWAFGVTMWEIATRG--------------MTPYPGVQNHEMYDYLLH 815 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 G RL +P+ C E+Y +M +CW T+ RPTF L L+ + E Sbjct 816 GHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLE 859 Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 71/313 (23%), Positives = 122/313 (39%), Gaps = 50/313 (16%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 ++L +D+ + LG+G +V EG L+ E G Sbjct 575 NKLEDVVIDRNLLILGKILGEGEFGSVMEGNLKQED---------------------GTS 613 Query 637 LRVVLKV--LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-----GPENIMVTEY 689 L+V +K LD S F A+ M SH ++ + GVC+ P+ +++ + Sbjct 614 LKVAVKTMKLDNSSQREIEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPF 673 Query 690 VEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 +++G L +L R H+P+ + +A + YL N+N +H ++ RN +L Sbjct 674 MKYGDLHTYLLYSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCML-- 731 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKW 798 + ++D G+ S + + W+A E L ++ D W Sbjct 732 -----RDDMTVCVADFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRV--YTSKSDVW 784 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 FG T+ EI G P E + HRL PE +L + C +P R Sbjct 785 AFGVTMWEIATRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDR 844 Query 857 PSFRTILRDLTRL 869 P+F + L +L Sbjct 845 PTFSVLRLQLEKL 857 >sp|Q54Y55|SHKC_DICDI Dual specificity protein kinase shkC OS=Dictyostelium discoideum OX=44689 GN=shkC PE=3 SV=1 Length=506 Score = 249 bits (635), Expect = 1e-70, Method: Composition-based stats. Identities = 80/277 (29%), Positives = 131/277 (47%), Gaps = 31/277 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FGKV + VAVK L K + S +++E+ ++ +YH +I Sbjct 30 IGTGSFGKVYKG------RCRQKAVAVKLLHKQNFDAATLSAFRKEVHLMSKIYHPNICL 83 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQH- 1018 + G C G +V E VP G+L L I L + A+ G+ +LH + Sbjct 84 FMGACTIPG--RCVIVTELVPKGNLETLLHDQKIQLPLYLRMRMARDAALGINWLHESNP 141 Query 1019 -YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 ++HRD+ + N+L+D + VKI DFGL+ A+ + H+ + + + APE + + Sbjct 142 VFVHRDIKSSNLLVDENMRVKICDFGLS-ALKQKHKMLKDQSSAKGTPLYMAPEVMMFKE 200 Query 1078 FYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 F +SDV+SFG+ L+E+LT + KF E + + ER P Sbjct 201 FNESSDVYSFGIVLWEILTRKEPFSHHRELEKFREAVCVKH---------------ERPP 245 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P+ C + L++ CW+ E RP+F+ +I L V Sbjct 246 IPNDCLDSLRRLIEKCWDKEPISRPSFKEIISALDHV 282 Score = 233 bits (595), Expect = 3e-65, Method: Composition-based stats. Identities = 66/301 (22%), Positives = 114/301 (38%), Gaps = 48/301 (16%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + +EI +G G+ VY+GR R + V + Sbjct 17 PEIRPEEINFEELIGTGSFGKVYKGRCR--------------------------QKAVAV 50 Query 642 KVLDPSHHDIAL--AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 K+L + D A AF + LMS++ H ++ G C ++VTE V G L+ L Sbjct 51 KLLHKQNFDAATLSAFRKEVHLMSKIYHPNICLFMGACTIPGRCVIVTELVPKGNLETLL 110 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKL 757 ++ +P+ +M +A+ A +++L N VH ++ N+L+ + +K+ Sbjct 111 HDQKIQLPLYLRMRMARDAALGINWLHESNPVFVHRDIKSSNLLVDE-------NMRVKI 163 Query 758 SDPGVG------LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 D G+ + ++APE + + + D + FG L EI Sbjct 164 CDFGLSALKQKHKMLKDQSSAKGTPLYMAPEVMM--FKEFNESSDVYSFGIVLWEILTRK 221 Query 812 EAPLQSRSPS---EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 E R E + +P L L +C EP RPSF+ I+ L Sbjct 222 EPFSHHRELEKFREAVCVKHERPPIPNDCLDSLRRLIEKCWDKEPISRPSFKEIISALDH 281 Query 869 L 869 + Sbjct 282 V 282 >sp|Q9SJG2|Y2296_ARATH Probable receptor-like protein kinase At2g42960 OS=Arabidopsis thaliana OX=3702 GN=At2g42960 PE=3 SV=1 Length=494 Score = 248 bits (633), Expect = 1e-70, Method: Composition-based stats. Identities = 69/278 (25%), Positives = 117/278 (42%), Gaps = 19/278 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG +G V G VAVK L + G Q ++ E++ + + H+++++ Sbjct 189 LGEGGYGVVYRG-----KLVNGTEVAVKKLLNNLG-QAEKEFRVEVEAIGHVRHKNLVRL 242 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMAYLHAQ 1017 G C + + LV EYV G+L +L ++ + + +AYLH Sbjct 243 LGYCIEGVHR--MLVYEYVNSGNLEQWLHGAMRQHGNLTWEARMKIITGTAQALAYLHEA 300 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 +HRD+ A N+L+D++ K+ DFGLAK + G + R + APE Sbjct 301 IEPKVVHRDIKASNILIDDEFNAKLSDFGLAKLLDSGESHITTR--VMGTFGYVAPEYAN 358 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQMTVLRLTELLERGER 1133 SD++SFGV L E +T D P + L+ + + R E+++ Sbjct 359 TGLLNEKSDIYSFGVLLLEAITGRDPVDYGRPANEVNLVEWLKMMVGTRRAEEVVDPRLE 418 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + C + EA RP + +L++ Sbjct 419 PRPSKSALKRALLVSLRCVDPEAEKRPRMSQVARMLES 456 Score = 218 bits (555), Expect = 4e-60, Method: Composition-based stats. Identities = 69/335 (21%), Positives = 111/335 (33%), Gaps = 62/335 (19%) Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 + L + ++ LG+G VY G+L Sbjct 169 HWFTLRDLELATNRFAPVNVLGEGGYGVVYRGKLVNG----------------------- 205 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 V +K L + F + V H +L + G C+ G ++V EYV G Sbjct 206 --TEVAVKKLLNNLGQAEKEFRVEVEAIGHVRHKNLVRLLGYCIEGVHRMLVYEYVNSGN 263 Query 695 LDVWLR---RERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLA 748 L+ WL R+ G++ +M + A AL+YL +VH ++ NIL+ Sbjct 264 LEQWLHGAMRQHGNLTWEARMKIITGTAQALAYLHEAIEPKVVHRDIKASNILID----- 318 Query 749 EGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 KLSD G+ S E + ++APE G L+ D + FG Sbjct 319 --DEFNAKLSDFGLAKLLDSGESHITTRVMGTFGYVAPEYANTGL--LNEKSDIYSFGVL 374 Query 804 LLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLAT------------LTS 846 LLE + P + E R E P+L ++ Sbjct 375 LLEAITGRDPVDYGRPANEVNLVEWLKMMVGTRRAEEVVDPRLEPRPSKSALKRALLVSL 434 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 +C+ E +RP + R L + + Sbjct 435 RCVDPEAEKRPRMSQVARMLESDEHPFHKERRNKR 469 >sp|Q60805|MERTK_MOUSE Tyrosine-protein kinase Mer OS=Mus musculus OX=10090 GN=Mertk PE=1 SV=1 Length=994 Score = 259 bits (663), Expect = 1e-70, Method: Composition-based stats. Identities = 89/283 (31%), Positives = 134/283 (47%), Gaps = 27/283 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG FG V DGT + VAVK +K D + + E ++ H ++I+ Sbjct 588 LGEGEFGSVMEGNLK-QEDGTSQKVAVKTMKLDNFSQREIEEFLSEAACMKDFNHPNVIR 646 Query 962 YKGCCED---QGEKSLQLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFAQQICEGM 1011 G C + QG +++ ++ G L +L + L LL F I +GM Sbjct 647 LLGVCIELSSQGIPKPMVILPFMKYGDLHTFLLYSRLNTGPKYIHLQTLLKFMMDIAQGM 706 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 YL ++++HRDLAARN +L +D V + DFGL+K + G +YYR PV W A E Sbjct 707 EYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSG-DYYRQGRIAKMPVKWIAIE 765 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 L + + SDVW+FGVT++E+ T + + + L G Sbjct 766 SLADRVYTSKSDVWAFGVTMWEITTRG--------------MTPYPGVQNHEMYDYLLHG 811 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 RL +P+ C E+Y +M +CW + RPTF L L+ + E Sbjct 812 HRLKQPEDCLDELYDIMYSCWSADPLDRPTFSVLRLQLEKLSE 854 Score = 231 bits (589), Expect = 3e-61, Method: Composition-based stats. Identities = 66/313 (21%), Positives = 120/313 (38%), Gaps = 50/313 (16%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 ++L +D+ + LG+G +V EG L+ E G Sbjct 570 NKLEDVVIDRNLLVLGKVLGEGEFGSVMEGNLKQED---------------------GTS 608 Query 637 LRVVLKV--LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-----GPENIMVTEY 689 +V +K LD F A+ M +H ++ + GVC+ P+ +++ + Sbjct 609 QKVAVKTMKLDNFSQREIEEFLSEAACMKDFNHPNVIRLLGVCIELSSQGIPKPMVILPF 668 Query 690 VEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 +++G L +L R ++ + + +A + YL N+N +H ++ RN +L Sbjct 669 MKYGDLHTFLLYSRLNTGPKYIHLQTLLKFMMDIAQGMEYLSNRNFLHRDLAARNCML-- 726 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKW 798 + ++D G+ S + + W+A E L ++ D W Sbjct 727 -----RDDMTVCVADFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRV--YTSKSDVW 779 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 FG T+ EI G P E + HRL PE +L + C + +P R Sbjct 780 AFGVTMWEITTRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDELYDIMYSCWSADPLDR 839 Query 857 PSFRTILRDLTRL 869 P+F + L +L Sbjct 840 PTFSVLRLQLEKL 852 >sp|Q62190|RON_MOUSE Macrophage-stimulating protein receptor OS=Mus musculus OX=10090 GN=Mst1r PE=1 SV=3 Length=1378 Score = 263 bits (671), Expect = 1e-70, Method: Composition-based stats. Identities = 98/287 (34%), Positives = 143/287 (50%), Gaps = 23/287 (8%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + + + +G+GHFG V Y D + T A+K+L Q + +E Sbjct 1053 PHEQVVIHTDQVIGKGHFGVVYHGEYTDGAQNQT--HCAIKSLSRITEVQEVEAFLREGL 1110 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQI 1007 ++R L+H +I+ G L + Y+ G L ++ P+ + + L+ F Q+ Sbjct 1111 LMRGLHHPNILALIGIMLPPEGLPRVL-LPYMRHGDLLHFIRSPQRNPTVKDLVSFGLQV 1169 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE--DGDSPV 1065 GM YL Q ++HRDLAARN +LD VK+ DFGLA+ V + EYY VR+ PV Sbjct 1170 ACGMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARGVLD-KEYYSVRQHRHARLPV 1228 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 W A E L+ Y+F SDVWSFGV L+ELLT + L+ Sbjct 1229 KWMALESLQTYRFTTKSDVWSFGVLLWELLTRGAP--------------PYPHIDPFDLS 1274 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 L +G RLP+P+ CP +YH+M CWE + + RPTF L+ +K V Sbjct 1275 HFLAQGRRLPQPEYCPDSLYHVMLRCWEADPAARPTFRALVLEVKQV 1321 Score = 227 bits (578), Expect = 3e-59, Method: Composition-based stats. Identities = 68/325 (21%), Positives = 126/325 (39%), Gaps = 49/325 (15%) Query 556 GETSNLIIMRGARASPRTLN---LSQLSFHRVDQKEITQLS--HLGQGTRTNVYEGRLRV 610 + +++ ++R + L+ L+++ + +++ + +G+G VY G Sbjct 1021 RDGTSVPLLRTESIRLQDLDRMLLAEVKDVLIPHEQVVIHTDQVIGKGHFGVVYHGEYTD 1080 Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTH 669 +K L + AF LM + H + Sbjct 1081 GAQNQTHC---------------------AIKSLSRITEVQEVEAFLREGLLMRGLHHPN 1119 Query 670 LAFVHGVCV--RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 + + G+ + G ++ Y+ HG L ++R + + + + Q+A + YL Sbjct 1120 ILALIGIMLPPEGLPRVL-LPYMRHGDLLHFIRSPQRNPTVKDLVSFGLQVACGMEYLAE 1178 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER--------IPWL 779 + VH ++ RN +L S +K++D G+ G L +E R + W+ Sbjct 1179 QKFVHRDLAARNCMLDE-------SFTVKVADFGLARGVLDKEYYSVRQHRHARLPVKWM 1231 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SC 838 A E L +T D W FG L E+ G P P + HF + RLP+P C Sbjct 1232 ALESLQT--YRFTTKSDVWSFGVLLWELLTRGAPPYPHIDPFDLSHFLAQGRRLPQPEYC 1289 Query 839 PQ-LATLTSQCLTYEPTQRPSFRTI 862 P L + +C +P RP+FR + Sbjct 1290 PDSLYHVMLRCWEADPAARPTFRAL 1314 >sp|D3ZG83|M3K10_RAT Mitogen-activated protein kinase kinase kinase 10 OS=Rattus norvegicus OX=10116 GN=Map3k10 PE=1 SV=3 Length=940 Score = 259 bits (661), Expect = 1e-70, Method: Composition-based stats. Identities = 93/341 (27%), Positives = 139/341 (41%), Gaps = 41/341 (12%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 + + + P N + P L+ +G G FGKV Sbjct 56 EGWWTGQLPSGRVGVFPSNYVAPAAPAAPTDLQLPQEIPFHELQLEEIIGVGGFGKVYRA 115 Query 915 CYDPTNDGTGEMVAVK--ALKADCGPQHR-SGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 + GE VAVK L + P +QE + L H +II +G C Sbjct 116 LWR------GEEVAVKAARLDPERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSP-- 167 Query 972 KSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028 +L LVMEY G+L L + L+ +A Q+ GM YLH IHRDL + N Sbjct 168 PNLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSIN 227 Query 1029 VLLDN--------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 +L+ D ++KI DFGLA+ + + W APE ++ F Sbjct 228 ILILEAIENHNLADTVLKITDFGLAR-----EWHKTTKMSAAGTYAWMAPEVIRLSLFSK 282 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 +SDVWSFGV L+ELLT P + ++ + +A G + LP P C Sbjct 283 SSDVWSFGVLLWELLTG-----EVPYREIDALAVAYG---------VAMNKLTLPIPSTC 328 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 P L++ CW+ + RP F +++ L+ + + Q P Sbjct 329 PEPFARLLEECWDPDPHGRPDFGSILKQLEVIEQSALFQMP 369 Score = 223 bits (568), Expect = 9e-59, Method: Composition-based stats. Identities = 79/382 (21%), Positives = 135/382 (35%), Gaps = 44/382 (12%) Query 527 RELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ 586 + L +GD+ + + + G + + A A+P L L Q + Sbjct 40 GDRVQVLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPAAPAAPTDLQLPQ----EIPF 95 Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 E+ +G G VY R G+E+ V LDP Sbjct 96 HELQLEEIIGVGGFGKVYRALWR------------------------GEEVAVKAARLDP 131 Query 647 SHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 A + A L + H ++ + G C+ P +V EY G L L R Sbjct 132 ERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSPPNLCLVMEYARGGALSRVLAGRR- 190 Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFI-KLSDP 760 VP + A Q+A ++YL N ++H ++ NIL+ + + K++D Sbjct 191 -VPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDF 249 Query 761 GVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 G+ ++ W+APE + + S + D W FG L E+ GE P + Sbjct 250 GLAREWHKTTKMSAAGTYAWMAPEVIR--LSLFSKSSDVWSFGVLLWELL-TGEVPYREI 306 Query 819 SPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + + +P A L +C +P RP F +IL+ L ++ L Sbjct 307 DALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKQLEVIEQSALF 366 Query 876 DVLTVNPDSPASDPTVFHKRYL 897 + + S D + + Sbjct 367 QMPLESFHSLQEDWKLEIQHMF 388 >sp|Q17R13|ACK1_BOVIN Activated CDC42 kinase 1 OS=Bos taurus OX=9913 GN=TNK2 PE=1 SV=1 Length=1039 Score = 260 bits (664), Expect = 1e-70, Method: Composition-based stats. Identities = 108/276 (39%), Positives = 150/276 (54%), Gaps = 21/276 (8%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLY 955 LG+G FG V +D + T VAVK LK D P+ + +E++ + +L Sbjct 127 HLFEKLGDGSFGVVRRGEWDAPSGKT-VSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLD 185 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAY 1013 H ++I+ G K+ V E PLGSL D L +H L L +A Q+ EGM Y Sbjct 186 HRNLIRLYGVVLTPPMKT---VTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGY 242 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 L A+ +IHRDLAARN+LL LVKIGDFGL +A+P+ ++Y ++E P W APE L Sbjct 243 LEAKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESL 302 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 K F +ASD W FGVTL+E+ T+ IG+ Q+ L ++ + GER Sbjct 303 KTRTFSHASDTWMFGVTLWEMFTYGQEP---------WIGLNGSQI----LHKIDKEGER 349 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 LPRP+ CP ++Y++M CW + RPTF L L Sbjct 350 LPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFL 385 Score = 225 bits (574), Expect = 3e-59, Method: Composition-based stats. Identities = 85/353 (24%), Positives = 133/353 (38%), Gaps = 54/353 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + +K++ LG G+ V G G+ + V +K Sbjct 121 IGEKDLHLFEKLGDGSFGVVRRGEW---------------------DAPSGKTVSVAVKC 159 Query 644 LDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 L P S + F + M + H +L ++GV + P VTE G L LR Sbjct 160 LKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKT-VTELAPLGSLLDRLR 218 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + +GH + A Q+A + YLE K +H ++ RN+LLA T +K+ D Sbjct 219 KHQGHFLLGTLSRYAVQVAEGMGYLEAKRFIHRDLAARNLLLA-------TRDLVKIGDF 271 Query 761 GVGLG-------ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ + +E R W APE L + S A D W FG TL E+ G+ Sbjct 272 GLMRALPQNDDHYVMQEHRKVPFAWCAPESLKT--RTFSHASDTWMFGVTLWEMFTYGQE 329 Query 814 PLQSRSPSEKEH-FYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P + S+ H + RLP P CPQ + + QC ++P RP+F + L Q Sbjct 330 PWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQ 389 Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923 P ++ + ++ G+ Y + N T Sbjct 390 PTDMRALQDFEEPDKLHIQMNDVITVIE----------GRAENYWWRGQNTRT 432 >sp|Q24145|SHARK_DROME Tyrosine-protein kinase Shark OS=Drosophila melanogaster OX=7227 GN=Shark PE=1 SV=2 Length=939 Score = 258 bits (660), Expect = 1e-70, Method: Composition-based stats. Identities = 92/275 (33%), Positives = 144/275 (52%), Gaps = 27/275 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEM----VAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 ++G G FG V G GE VA+K L + ++ + +E ++ L H+ Sbjct 667 EIGHGEFGSVHSGWL-LRKSGAGEESRLEVAIKMLSDEHS--NKQEFLREASVMMRLEHK 723 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYL 1014 I++ G + L +V E PLGS+ Y+ H + A+L ++A QI GM YL Sbjct 724 CIVRLIGI---AKGEMLMMVQELAPLGSMLQYILDHGHEITANAELKVWASQIACGMHYL 780 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 +QH++HRDLAARN+LL KI DFG+++++ G Y+ + G P+ WYAPE Sbjct 781 ESQHFVHRDLAARNILLTARHQAKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESFN 840 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 F +ASDVWSFGVT++E+ + G+++ + +L++ GERL Sbjct 841 LGIFSHASDVWSFGVTIWEMFSLGAP--------------PYGEISNVDAIKLVDSGERL 886 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P+P+ CP +Y +M++CW+ RPTF L Sbjct 887 PQPNLCPAYIYAVMQSCWKERPKDRPTFVYLTEFF 921 Score = 233 bits (593), Expect = 7e-62, Method: Composition-based stats. Identities = 74/361 (20%), Positives = 134/361 (37%), Gaps = 43/361 (12%) Query 520 GRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQL 579 G + ++ + L + + E ++ + R +P T + +++ Sbjct 590 GNGYQPTMDVLSLLDQQIKAPAVARLNSLGPNASTESEMASYL-HRKCSGTPSTPSATEV 648 Query 580 SFHR----VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 + ++ +++ +G G +V+ G L + G Sbjct 649 EAAKLRFFIEPEKLVLDREIGHGEFGSVHSGWLLRK-----------------SGAGEES 691 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 L V +K+L H + F AS+M ++ H + + G+ +G +MV E G + Sbjct 692 RLEVAIKMLSDEHSN-KQEFLREASVMMRLEHKCIVRLIGI-AKGEMLMMVQELAPLGSM 749 Query 696 DVWLRRERGHVPMAWKMVV-AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 ++ + ++ V A Q+A + YLE+++ VH ++ RNILL Sbjct 750 LQYILDHGHEITANAELKVWASQIACGMHYLESQHFVHRDLAARNILLT-------ARHQ 802 Query 755 IKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 K+SD G+ + I W APE G S A D W FG T+ E+ Sbjct 803 AKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESFNLGI--FSHASDVWSFGVTIWEM 860 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTILRD 865 G P S + RLP+P+ CP + + C P RP+F + Sbjct 861 FSLGAPPYGEISNVDAIKLVDSGERLPQPNLCPAYIYAVMQSCWKERPKDRPTFVYLTEF 920 Query 866 L 866 Sbjct 921 F 921 Score = 40.0 bits (92), Expect = 0.17, Method: Composition-based stats. Identities = 21/151 (14%), Positives = 47/151 (31%), Gaps = 8/151 (5%) Query 450 GIHGPLLEPFVQAKLRP--EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPI 507 HG L L+ EDG +L+ S++ +L++ + + ++R+ Sbjct 10 WYHGNLSREAADELLKQGYEDGTFLVRESSTAAGDFVLSLLCQGEVC----HYQVRRHGG 65 Query 508 EQQDGAFVLEGWGRSFPSVRELGAALQGCLLRA-GDDCFSLRRCCLPQPGETSNLIIMRG 566 E + + + + L Q L R P + + + Sbjct 66 EDAFFSIDDKVQTKILHGLDTLVDYYQQAANGLPTKLTVPLIRDLPPHNTRSHGVTNLLH 125 Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQ 597 RA+ + + + + + GQ Sbjct 126 -RATSKNESKVVFELLKCGYRNFDAKNQDGQ 155 >sp|O73798|IGF1R_XENLA Insulin-like growth factor 1 receptor OS=Xenopus laevis OX=8355 GN=igf1r PE=1 SV=1 Length=1358 Score = 263 bits (671), Expect = 1e-70, Method: Composition-based stats. Identities = 90/309 (29%), Positives = 144/309 (47%), Gaps = 29/309 (9%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE-MVAVKALK 933 + D + + R+LG+G FG V E VA+K + Sbjct 973 NPEYFSAAEMYVPDKWEVPREKITMNRELGQGSFGMVYEGIAKGVVKDEAETKVAIKTVN 1032 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991 + R + E +++ H+++ G QG+ +L ++ME + G L+ YL Sbjct 1033 EAASMRERIEFLNEASVMKEFNCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSL 1090 Query 992 ---------RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 + + L +++ A +I +GM+YL+A ++HRDLAARN ++ D VKIGDF Sbjct 1091 RPDTESNSGQPTPSLKKMIQMAGEIADGMSYLNANKFVHRDLAARNCMVTEDFTVKIGDF 1150 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 G+ + + E +YYR G PV W +PE LK+ F SDVWSFGV L+E+ T Sbjct 1151 GMTRDIYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTTNSDVWSFGVVLWEIAT------ 1203 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 L M+ ++ + G L +PD CP ++ LM+ CW+ RP+F Sbjct 1204 --------LAEQPYQGMSNEQVLRFVMEGGLLEKPDNCPDMLFELMRMCWQFNPKMRPSF 1255 Query 1163 ENLIPILKT 1171 +I +K Sbjct 1256 LEIISSIKD 1264 Score = 247 bits (630), Expect = 1e-65, Method: Composition-based stats. Identities = 71/317 (22%), Positives = 121/317 (38%), Gaps = 49/317 (15%) Query 567 ARASPRTLNLSQL---SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 A +P + +++ V +++IT LGQG+ VYEG + + Sbjct 970 ASVNPEYFSAAEMYVPDKWEVPREKITMNRELGQGSFGMVYEGIAKGVVKDEA------- 1022 Query 624 EDPLVPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 E +V +K ++ + + F AS+M + + H+ + GV +G Sbjct 1023 ------------ETKVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQP 1070 Query 683 NIMVTEYVEHGPLDVWLRRERGH---------VPMAWKMVVAQQLASALSYLENKNLVHG 733 +++ E + G L +LR R + + +A ++A +SYL VH Sbjct 1071 TLVIMELMTRGDLKSYLRSLRPDTESNSGQPTPSLKKMIQMAGEIADGMSYLNANKFVHR 1130 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGG 787 ++ RN ++ +K+ D G+ + + + W++PE L G Sbjct 1131 DLAARNCMVTE-------DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDG 1183 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLT 845 +T D W FG L EI E P Q S + F L P+ L L Sbjct 1184 V--FTTNSDVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEKPDNCPDMLFELM 1241 Query 846 SQCLTYEPTQRPSFRTI 862 C + P RPSF I Sbjct 1242 RMCWQFNPKMRPSFLEI 1258 >sp|Q9M8S2|LIPG2_ARATH Receptor-like kinase LIP2 OS=Arabidopsis thaliana OX=3702 GN=LIP2 PE=1 SV=1 Length=558 Score = 250 bits (638), Expect = 2e-70, Method: Composition-based stats. Identities = 83/302 (27%), Positives = 133/302 (44%), Gaps = 18/302 (6%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 ++ LGEG FG+V Y T TG++VAVK L G ++ E+ L L Sbjct 63 NFRQECLLGEGGFGRV----YKGTLKSTGQVVAVKQLDKH-GLHGNKEFQAEVLSLGQLD 117 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQICEG 1010 H +++K G C D ++ LV +Y+ GSL+D+L + + A +G Sbjct 118 HPNLVKLIGYCADGDQR--LLVYDYISGGSLQDHLHEPKADSDPMDWTTRMQIAYAAAQG 175 Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVF 1066 + YLH + I+RDL A N+LLD+D K+ DFGL K P G + + Sbjct 176 LDYLHDKANPPVIYRDLKASNILLDDDFSPKLSDFGLHKLGPGTGDKMMALSSRVMGTYG 235 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQG-QMTVLRL 1124 + APE + SDV+SFGV L EL+T + + P L+ AQ R Sbjct 236 YSAPEYTRGGNLTLKSDVYSFGVVLLELITGRRALDTTRPNDEQNLVSWAQPIFRDPKRY 295 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 ++ + ++ + + C + EAS RP +++ L + + P+ Sbjct 296 PDMADPVLENKFSERGLNQAVAIASMCVQEEASARPLISDVMVALSFLSMPTEDGIPTTV 355 Query 1185 SV 1186 + Sbjct 356 PI 357 Score = 228 bits (580), Expect = 7e-63, Method: Composition-based stats. Identities = 75/354 (21%), Positives = 120/354 (34%), Gaps = 68/354 (19%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRV 610 P+P + S T +L +F + K Q LG+G VY+G L+ Sbjct 27 PKPDDRRRAEETEEIEQSEGT-SLKIFTFRELATATKNFRQECLLGEGGFGRVYKGTLKS 85 Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670 G V +K LD F + Q+ H +L Sbjct 86 TGQ------------------------VVAVKQLDKHGLHGNKEFQAEVLSLGQLDHPNL 121 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER---GHVPMAWKMVVAQQLASALSYLEN 727 + G C G + ++V +Y+ G L L + + +M +A A L YL + Sbjct 122 VKLIGYCADGDQRLLVYDYISGGSLQDHLHEPKADSDPMDWTTRMQIAYAAAQGLDYLHD 181 Query 728 K---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR--------EERVERI 776 K +++ ++ NILL KLSD G+ + Sbjct 182 KANPPVIYRDLKASNILLDDDFSP-------KLSDFGLHKLGPGTGDKMMALSSRVMGTY 234 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ------ 830 + APE GG +L+ D + FG LLE+ A +R E+ Q Sbjct 235 GYSAPEYTRGG--NLTLKSDVYSFGVVLLELITGRRALDTTRPNDEQNLVSWAQPIFRDP 292 Query 831 HRLPEPSCPQLAT------------LTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 R P+ + P L + S C+ E + RP ++ L+ L Sbjct 293 KRYPDMADPVLENKFSERGLNQAVAIASMCVQEEASARPLISDVMVALSFLSMP 346 >sp|Q8MY85|FGFR2_DUGJA Fibroblast growth factor receptor 2 OS=Dugesia japonica OX=6161 GN=FGFR2 PE=2 SV=1 Length=887 Score = 258 bits (658), Expect = 2e-70, Method: Composition-based stats. Identities = 95/311 (31%), Positives = 138/311 (44%), Gaps = 38/311 (12%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT-GEMVAVKALKADCGPQHRSGWKQEI 948 +F + L +GEG FG V ++ + VA+K L G Q QE+ Sbjct 578 WIFSRDSLIIGSKIGEGAFGIVYSALVKSFSENSASVEVAIKTLHTSFGDQDVINLIQEL 637 Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------------- 994 ++++ + H HII G C D G +V+E G+LRD+L Sbjct 638 EMMKIIGRHRHIISLYGACIDNGHP--YMVIELAKHGNLRDFLRAQRSQSKVGEIQNSGG 695 Query 995 ----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 + + L F+ +I EGM YL ++ IHRDLAARNVL+D +KI DFGL + V Sbjct 696 LVTRLTVTDFLRFSIEIAEGMEYLSSRKIIHRDLAARNVLVDQYVEMKIADFGLTRIV-- 753 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 YYR DG P+ W APECL + + SDVWS+G+ L+E+ T Sbjct 754 -ENYYRKTTDGRLPIKWMAPECLLDRVYTVKSDVWSYGIVLWEIFT-------------- 798 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + + + + L G R +P E+Y LM W + R TF +I L Sbjct 799 MGQTPYPTIQSDGMHQALRNGIRNEKPALASDEMYRLMLTIWNDDPLERHTFSEIIDKLT 858 Query 1171 TVHEKYQGQAP 1181 + G +P Sbjct 859 HIQLSNGGSSP 869 Score = 216 bits (551), Expect = 8e-57, Method: Composition-based stats. Identities = 62/333 (19%), Positives = 120/333 (36%), Gaps = 51/333 (15%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + + S +G+G VY ++ + V + Sbjct 578 WIFSRDSLIIGSKIGEGAFGIVYSALVKSFSENSAS-------------------VEVAI 618 Query 642 KVLDPS-HHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 K L S + + +M + H H+ ++G C+ MV E +HG L +L Sbjct 619 KTLHTSFGDQDVINLIQELEMMKIIGRHRHIISLYGACIDNGHPYMVIELAKHGNLRDFL 678 Query 700 RRERGH---------------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 R +R + + + + ++A + YL ++ ++H ++ RN+L+ + Sbjct 679 RAQRSQSKVGEIQNSGGLVTRLTVTDFLRFSIEIAEGMEYLSSRKIIHRDLAARNVLVDQ 738 Query 745 LGLAEGTSPFIKLSDPGVGL--GALSREERVERIP--WLAPECLPGGANSLSTAMDKWGF 800 +K++D G+ R+ R+P W+APECL + D W + Sbjct 739 YVE-------MKIADFGLTRIVENYYRKTTDGRLPIKWMAPECLLDRV--YTVKSDVWSY 789 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPS 858 G L EI G+ P + + R P + ++ L +P +R + Sbjct 790 GIVLWEIFTMGQTPYPTIQSDGMHQALRNGIRNEKPALASDEMYRLMLTIWNDDPLERHT 849 Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTV 891 F I+ LT +Q N + +S+ Sbjct 850 FSEIIDKLTHIQLSNGGSSPKRDYLEISSNQCY 882 >sp|Q66L42|M3K10_MOUSE Mitogen-activated protein kinase kinase kinase 10 OS=Mus musculus OX=10090 GN=Map3k10 PE=1 SV=2 Length=940 Score = 258 bits (660), Expect = 2e-70, Method: Composition-based stats. Identities = 94/341 (28%), Positives = 139/341 (41%), Gaps = 41/341 (12%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 + + + P N S P L+ +G G FGKV Sbjct 56 EGWWTGQLPSGRVGVFPSNYVAPAAPAAPSDLQLPQEIPFHELQLEEIIGVGGFGKVYRA 115 Query 915 CYDPTNDGTGEMVAVK--ALKADCGPQHR-SGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 + GE VAVK L + P +QE + L H +II +G C Sbjct 116 VWR------GEEVAVKAARLDPERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSP-- 167 Query 972 KSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028 +L LVMEY G+L L + L+ +A Q+ GM YLH IHRDL + N Sbjct 168 PNLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSIN 227 Query 1029 VLLDN--------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 +L+ D ++KI DFGLA+ + + W APE ++ F Sbjct 228 ILILEAIENHNLADTVLKITDFGLAR-----EWHKTTKMSAAGTYAWMAPEVIRLSLFSK 282 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 +SDVWSFGV L+ELLT P + ++ + +A G + LP P C Sbjct 283 SSDVWSFGVLLWELLTG-----EVPYREIDALAVAYG---------VAMNKLTLPIPSTC 328 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 P L++ CW+ + RP F +++ L+ + + Q P Sbjct 329 PEPFARLLEECWDPDPHGRPDFGSILKQLEVIEQSALFQMP 369 Score = 224 bits (570), Expect = 6e-59, Method: Composition-based stats. Identities = 79/382 (21%), Positives = 135/382 (35%), Gaps = 44/382 (12%) Query 527 RELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ 586 + L +GD+ + + + G + + A A+P L L Q + Sbjct 40 GDRVQVLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPAAPAAPSDLQLPQ----EIPF 95 Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 E+ +G G VY R G+E+ V LDP Sbjct 96 HELQLEEIIGVGGFGKVYRAVWR------------------------GEEVAVKAARLDP 131 Query 647 SHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 A + A L + H ++ + G C+ P +V EY G L L R Sbjct 132 ERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSPPNLCLVMEYARGGALSRVLAGRR- 190 Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFI-KLSDP 760 VP + A Q+A ++YL N ++H ++ NIL+ + + K++D Sbjct 191 -VPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDF 249 Query 761 GVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 G+ ++ W+APE + + S + D W FG L E+ GE P + Sbjct 250 GLAREWHKTTKMSAAGTYAWMAPEVIR--LSLFSKSSDVWSFGVLLWELL-TGEVPYREI 306 Query 819 SPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + + +P A L +C +P RP F +IL+ L ++ L Sbjct 307 DALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKQLEVIEQSALF 366 Query 876 DVLTVNPDSPASDPTVFHKRYL 897 + + S D + + Sbjct 367 QMPLESFHSLQEDWKLEIQHMF 388 >sp|Q6NKZ9|Y4345_ARATH Probable receptor-like serine/threonine-protein kinase At4g34500 OS=Arabidopsis thaliana OX=3702 GN=At4g34500 PE=2 SV=1 Length=437 Score = 246 bits (628), Expect = 2e-70, Method: Composition-based stats. Identities = 73/277 (26%), Positives = 122/277 (44%), Gaps = 17/277 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG +G V + G + AVK L + G Q +K E++ + + H++++ Sbjct 151 IGEGGYGVVYRADF-----SDGSVAAVKNLLNNKG-QAEKEFKVEVEAIGKVRHKNLVGL 204 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQICEGMAYLHA- 1016 G C D + LV EY+ G+L +L + + A +G+AYLH Sbjct 205 MGYCADSAQSQRMLVYEYIDNGNLEQWLHGDVGPVSPLTWDIRMKIAIGTAKGLAYLHEG 264 Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 +HRD+ + N+LLD K+ DFGLAK + G E V + +PE Sbjct 265 LEPKVVHRDVKSSNILLDKKWNAKVSDFGLAKLL--GSETSYVTTRVMGTFGYVSPEYAS 322 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 SDV+SFGV L E++T S P + L+ +G + R E+++ + Sbjct 323 TGMLNECSDVYSFGVLLMEIITGRSPVDYSRPPGEMNLVDWFKGMVASRRGEEVIDPKIK 382 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 P + + C + ++S RP +I +L+ Sbjct 383 TSPPPRALKRALLVCLRCIDLDSSKRPKMGQIIHMLE 419 Score = 207 bits (527), Expect = 5e-57, Method: Composition-based stats. Identities = 65/336 (19%), Positives = 114/336 (34%), Gaps = 64/336 (19%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 L + + + + +G+G VY D Sbjct 134 SLKDLEIATRGFSDDNMIGEGGYGVVYRA-------------------------DFSDGS 168 Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG--PENIMVTEYVEHGPL 695 +K L + F + +V H +L + G C + ++V EY+++G L Sbjct 169 VAAVKNLLNNKGQAEKEFKVEVEAIGKVRHKNLVGLMGYCADSAQSQRMLVYEYIDNGNL 228 Query 696 DVWLRRERGHV-PMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAE 749 + WL + G V P+ W +M +A A L+YL +VH +V NILL + Sbjct 229 EQWLHGDVGPVSPLTWDIRMKIAIGTAKGLAYLHEGLEPKVVHRDVKSSNILLDKK---- 284 Query 750 GTSPFIKLSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 K+SD G+ + + +++PE G L+ D + FG L Sbjct 285 ---WNAKVSDFGLAKLLGSETSYVTTRVMGTFGYVSPEYASTGM--LNECSDVYSFGVLL 339 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQ-----HRLPEPSCPQLAT------------LTSQ 847 +EI SR P E + R E P++ T + + Sbjct 340 MEIITGRSPVDYSRPPGEMNLVDWFKGMVASRRGEEVIDPKIKTSPPPRALKRALLVCLR 399 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 C+ + ++RP I+ L + + Sbjct 400 CIDLDSSKRPKMGQIIHMLEAEDFPFRPEHRSNQER 435 >sp|Q9SY89|Y1661_ARATH Putative G-type lectin S-receptor-like serine/threonine-protein kinase At1g61610 OS=Arabidopsis thaliana OX=3702 GN=At1g61610 PE=3 SV=1 Length=842 Score = 257 bits (656), Expect = 2e-70, Method: Composition-based stats. Identities = 76/278 (27%), Positives = 122/278 (44%), Gaps = 16/278 (6%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG+G FG V + G +AVK L + Q +K EI ++ L H +++ Sbjct 529 NKLGQGGFGTVYKGNF-----SEGREIAVKRL-SGKSKQGLEEFKNEILLIAKLQHRNLV 582 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016 + GCC + EK L+ EY+P SL +L + S+ + I G+ YLH Sbjct 583 RLLGCCIEDNEK--MLLYEYMPNKSLDRFLFDESKQGSLDWRKRWEVIGGIARGLLYLHR 640 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRDL A N+LLD + KI DFG+A+ ++ + APE Sbjct 641 DSRLKIIHRDLKASNILLDTEMNPKISDFGMARIFNYRQDHANT-IRVVGTYGYMAPEYA 699 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 E F SDV+SFGV + E+++ + T LIG A + + E+++ + Sbjct 700 MEGIFSEKSDVYSFGVLILEIVSGRKNVSFRGTDHGSLIGYAWHLWSQGKTKEMIDPIVK 759 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 R H+ C + RP +++ +L++ Sbjct 760 DTRDVTEAMRCIHVGMLCTQDSVIHRPNMGSVLLMLES 797 Score = 236 bits (602), Expect = 2e-63, Method: Composition-based stats. Identities = 61/276 (22%), Positives = 102/276 (37%), Gaps = 56/276 (20%) Query 559 SNLIIMRGARASP---------RTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGR 607 S++I R +SP T +L SF V + + + LGQG VY+G Sbjct 484 SDIIENRDYSSSPIKVLVGDQVDTPDLPIFSFDSVASATGDFAEENKLGQGGFGTVYKG- 542 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667 + + + +K L F L++++ H Sbjct 543 ------------------------NFSEGREIAVKRLSGKSKQGLEEFKNEILLIAKLQH 578 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYL 725 +L + G C+ E +++ EY+ + LD +L E + W+ V +A L YL Sbjct 579 RNLVRLLGCCIEDNEKMLLYEYMPNKSLDRFLFDESKQGSLDWRKRWEVIGGIARGLLYL 638 Query 726 ENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERI 776 ++H ++ NILL T K+SD G+ R++ V Sbjct 639 HRDSRLKIIHRDLKASNILLD-------TEMNPKISDFGMARIFNYRQDHANTIRVVGTY 691 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 ++APE G S D + FG +LEI + Sbjct 692 GYMAPEYAMEGI--FSEKSDVYSFGVLILEIVSGRK 725 >sp|C0LGD7|Y1684_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g06840 OS=Arabidopsis thaliana OX=3702 GN=At1g06840 PE=1 SV=2 Length=953 Score = 259 bits (661), Expect = 2e-70, Method: Composition-based stats. Identities = 79/291 (27%), Positives = 127/291 (44%), Gaps = 25/291 (9%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 +G+G +GKV G+G +VA+K + Q + EI++L L Sbjct 623 DNFNSSTQIGQGGYGKVYKGTL-----GSGTVVAIKR-AQEGSLQGEKEFLTEIELLSRL 676 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGM 1011 +H +++ G C+++GE+ LV EY+ G+LRD + + + A L A +G+ Sbjct 677 HHRNLVSLLGFCDEEGEQ--MLVYEYMENGTLRDNISVKLKEPLDFAMRLRIALGSAKGI 734 Query 1012 AYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP----EGHEYYRVREDGDSP 1064 YLH HRD+ A N+LLD+ K+ DFGL++ P EG V Sbjct 735 LYLHTEANPPIFHRDIKASNILLDSRFTAKVADFGLSRLAPVPDMEGISPQHVSTVVKGT 794 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 + PE ++ SDV+S GV L EL T + I IA ++L Sbjct 795 PGYLDPEYFLTHQLTDKSDVYSLGVVLLELFTGMQPITHG-KNIVREINIAYESGSILST 853 Query 1125 TELLERGERL-PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + +R+ PD+C + L C E RP+ ++ L+ + E Sbjct 854 VD-----KRMSSVPDECLEKFATLALRCCREETDARPSMAEVVRELEIIWE 899 Score = 223 bits (568), Expect = 9e-59, Method: Composition-based stats. Identities = 60/372 (16%), Positives = 118/372 (32%), Gaps = 66/372 (18%) Query 565 RGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 R ++AS + + ++ + + +GQG VY+G L Sbjct 599 RSSKASLKIEGVKSFTYAELALATDNFNSSTQIGQGGYGKVYKGTL-------------- 644 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 G V +K F L+S++ H +L + G C E Sbjct 645 -----------GSGTVVAIKRAQEGSLQGEKEFLTEIELLSRLHHRNLVSLLGFCDEEGE 693 Query 683 NIMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGR 738 ++V EY+E+G L + + + + A ++ +A A + YL N + H ++ Sbjct 694 QMLVYEYMENGTLRDNISVKLKEPLDFAMRLRIALGSAKGILYLHTEANPPIFHRDIKAS 753 Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGA-----------LSREERVERIPWLAPECLPGG 787 NILL + K++D G+ A +L PE Sbjct 754 NILLD-------SRFTAKVADFGLSRLAPVPDMEGISPQHVSTVVKGTPGYLDPEYFLT- 805 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-----------PEP 836 + L+ D + G LLE+ + ++ + + + P+ Sbjct 806 -HQLTDKSDVYSLGVVLLELFTGMQPITHGKNIVREINIAYESGSILSTVDKRMSSVPDE 864 Query 837 SCPQLATLTSQCLTYE----PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVF 892 + ATL +C E P+ R + + ++A ++ + Sbjct 865 CLEKFATLALRCCREETDARPSMAEVVRELEIIWELMPESHVAKTADLSETMTHPSSSSN 924 Query 893 HKRYLKKIRDLG 904 + Sbjct 925 SSIMKHHYTSMD 936 >sp|Q9NWZ3|IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 OS=Homo sapiens OX=9606 GN=IRAK4 PE=1 SV=1 Length=460 Score = 246 bits (629), Expect = 2e-70, Method: Composition-based stats. Identities = 85/374 (23%), Positives = 149/374 (40%), Gaps = 23/374 (6%) Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 + P + + KE +Q ++P C + TL + E + P + + Sbjct 99 LLLPDAVPKTANTLPSKEAITVQQKQMP--FCDKDRTLMTPVQNLEQSYMPPDSS-SPEN 155 Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926 L+ + + + +GEG FG V + T Sbjct 156 KSLEVSDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNT------T 209 Query 927 VAVKALKADCG---PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 VAVK L A + + + QEI ++ HE++++ G D + L LV Y+P Sbjct 210 VAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDD--LCLVYVYMPN 267 Query 984 GSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 GSL D L + AQ G+ +LH H+IHRD+ + N+LLD KI Sbjct 268 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKI 327 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGLA+A + + + + APE L+ SD++SFGV L E++T Sbjct 328 SDFGLARASEKFAQTVMTSRIVGTTA-YMAPEALRGE-ITPKSDIYSFGVVLLEIITGLP 385 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE-VYHLMKNCWETEASF 1158 + L L + + + + +++ ++ D E +Y + C + + Sbjct 386 AVDEHREPQLLLDIKEEIEDEEKTIEDYIDK--KMNDADSTSVEAMYSVASQCLHEKKNK 443 Query 1159 RPTFENLIPILKTV 1172 RP + + +L+ + Sbjct 444 RPDIKKVQQLLQEM 457 Score = 219 bits (559), Expect = 5e-61, Method: Composition-based stats. Identities = 72/388 (19%), Positives = 140/388 (36%), Gaps = 78/388 (20%) Query 524 PSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASP--RTLNLSQLSF 581 P + + ++ F + L P + M +SP ++L +S F Sbjct 106 PKTANTLPSKEAITVQQKQMPFCDKDRTLMTPVQNLEQSYMPPDSSSPENKSLEVSDTRF 165 Query 582 HRVDQKEITQ-------------LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 H E+ + +G+G VY+G + Sbjct 166 HSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYV-------------------- 205 Query 629 PGRDRGQELRVVLKVL----DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 V +K L D + ++ F + +M++ H +L + G G + Sbjct 206 ------NNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLC 259 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +V Y+ +G L L G P++W + +AQ A+ +++L + +H ++ NILL Sbjct 260 LVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILL 319 Query 743 ARLGLAEGTSPFIKLSDPGVGLGA------LSREERVERIPWLAPECLPGGANSLSTAMD 796 + K+SD G+ + + V ++APE L G ++ D Sbjct 320 DE-------AFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRG---EITPKSD 369 Query 797 KWGFGATLLEICFDGEAPLQSRSPS---------------EKEHFYQRQHRLPEPSCPQL 841 + FG LLEI A + R P +++ ++ + S + Sbjct 370 IYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAM 429 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRL 869 ++ SQCL + +RP + + + L + Sbjct 430 YSVASQCLHEKKNKRPDIKKVQQLLQEM 457 >sp|Q62956|ERBB4_RAT Receptor tyrosine-protein kinase erbB-4 OS=Rattus norvegicus OX=10116 GN=Erbb4 PE=1 SV=3 Length=1308 Score = 262 bits (669), Expect = 2e-70, Method: Composition-based stats. Identities = 98/272 (36%), Positives = 140/272 (51%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + VA+K L GP+ + E I+ ++ H H+++ Sbjct 724 LGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASVDHPHLVRL 783 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C +QLV + +P G L +Y+ H IG LL + QI +GM YL + + Sbjct 784 LGVCLSPT---IQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV 840 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ + VKI DFGLA+ + EG E + G P+ W A EC+ KF + Sbjct 841 HRDLAARNVLVKSPNHVKITDFGLARLL-EGDEKEYNADGGKMPIKWMALECIHYRKFTH 899 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T G + + +LLE+GERLP+P C Sbjct 900 QSDVWSYGVTIWELMTFG--------------GKPYDGIPTREIPDLLEKGERLPQPPIC 945 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW +A RP F+ L + Sbjct 946 TIDVYIVMVKCWMIDADSRPKFKELAAEFSRM 977 Score = 241 bits (615), Expect = 1e-63, Method: Composition-based stats. Identities = 68/338 (20%), Positives = 131/338 (39%), Gaps = 39/338 (12%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P +Q + + E+ ++ LG G VY+G EG Sbjct 699 TPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETV-------------- 744 Query 630 GRDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ V +K+L+ + + F + A +M+ V H HL + GVC+ P +VT+ Sbjct 745 ------KIPVAIKILNETTGPKANVEFMDEALIMASVDHPHLVRLLGVCL-SPTIQLVTQ 797 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + HG L ++ + ++ + Q+A + YLE + LVH ++ RN+L+ Sbjct 798 LMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPN-- 855 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 +K++D G+ + + I W+A EC+ + D W +G Sbjct 856 -----HVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIH--YRKFTHQSDVWSYGV 908 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860 T+ E+ G P E ++ RLP+P + + +C + RP F+ Sbjct 909 TIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYIVMVKCWMIDADSRPKFK 968 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898 + + +R+ ++ D K + Sbjct 969 ELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQN 1006 >sp|P13388|XMRK_XIPMA Melanoma receptor tyrosine-protein kinase OS=Xiphophorus maculatus OX=8083 GN=xmrk PE=2 SV=2 Length=1167 Score = 261 bits (666), Expect = 2e-70, Method: Composition-based stats. Identities = 95/289 (33%), Positives = 143/289 (49%), Gaps = 26/289 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V ++P + VA+K L+ P+ E ++ ++ H H+ + Sbjct 716 LGSGAFGTVYKGLWNPDGENIRIPVAIKVLREATSPKVNQEVLDEAYVMASVDHPHVCRL 775 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHYI 1020 G C ++QLV + +P G L DY+ +H + LL + QI +GM YL +H + Sbjct 776 LGICLTS---AVQLVTQLMPYGCLLDYVRQHQERICGQWLLNWCVQIAKGMNYLEERHLV 832 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVLL N VKI DFGL+K + + Y+ + G P+ W A E + ++ + + Sbjct 833 HRDLAARNVLLKNPNHVKITDFGLSKLLTADEKEYQA-DGGKVPIKWMALESILQWTYTH 891 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + + +LE GERLP+P C Sbjct 892 QSDVWSYGVTVWELMTFGSK--------------PYDGIPAKEIASVLENGERLPQPPIC 937 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK------YQGQAPSV 1183 EVY ++ CW + S RP F L+ + QG PS+ Sbjct 938 TIEVYMIILKCWMIDPSSRPRFRELVGEFSQMARDPSRYLVIQGNLPSL 986 Score = 237 bits (604), Expect = 1e-62, Method: Composition-based stats. Identities = 80/454 (18%), Positives = 159/454 (35%), Gaps = 42/454 (9%) Query 435 CHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAP 494 C + LV + +GP ++ + + + + + Sbjct 553 CVQCHQECLVQTDSLTCYGPGPANCSKSAHFQDGPQCIPRCPHGILGDGDTLIWKYADKM 612 Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 Q G G S S+ + + L R + Sbjct 613 GQCQPCHQNCTQGCSGPGLSGCRGDIVSHSSLAVGLVSGLLITVIVALLIVVLLRRRRIK 672 Query 555 PGETSNLIIMRGARASPRTL--NLSQLSFHRVDQK-EITQLSHLGQGTRTNVYEGRLRVE 611 T ++ P T +F R+ ++ E + LG G VY+G + Sbjct 673 RKRTIRCLLQEKELVEPLTPSGQAPNQAFLRILKETEFKKDRVLGSGAFGTVYKGLWNPD 732 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHL 670 G + V +KVL + + + A +M+ V H H+ Sbjct 733 GENI--------------------RIPVAIKVLREATSPKVNQEVLDEAYVMASVDHPHV 772 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730 + G+C+ +VT+ + +G L ++R+ + + W + Q+A ++YLE ++L Sbjct 773 CRLLGICLTSAVQ-LVTQLMPYGCLLDYVRQHQERICGQWLLNWCVQIAKGMNYLEERHL 831 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECL 784 VH ++ RN+LL +K++D G+ + E+ + I W+A E + Sbjct 832 VHRDLAARNVLLKNPN-------HVKITDFGLSKLLTADEKEYQADGGKVPIKWMALESI 884 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--A 842 + + D W +G T+ E+ G P E + RLP+P + Sbjct 885 LQ--WTYTHQSDVWSYGVTVWELMTFGSKPYDGIPAKEIASVLENGERLPQPPICTIEVY 942 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 + +C +P+ RP FR ++ + +++ Sbjct 943 MIILKCWMIDPSSRPRFRELVGEFSQMARDPSRY 976 >sp|D2IYS2|TORSO_BOMMO Tyrosine-protein kinase receptor torso OS=Bombyx mori OX=7091 GN=tor PE=1 SV=1 Length=807 Score = 256 bits (653), Expect = 2e-70, Method: Composition-based stats. Identities = 91/334 (27%), Positives = 136/334 (41%), Gaps = 71/334 (21%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 D + +GEG FG V P G+ VAVK LK + ++ E Sbjct 430 DHWEVRSDRVLLHEVIGEGAFGVVRRGTLAPG----GKSVAVKMLKEFPSQEEVRSFRSE 485 Query 948 IDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--------------- 991 +++++++ H H++ GCC + +V EY G L YL Sbjct 486 MELMKSVGAHPHVVSLVGCC---SGRKPLIVAEYCSRGDLLSYLRSSWDIIVSKHTAKYY 542 Query 992 ---------------------------------RHSIGLAQLLLFAQQICEGMAYLHAQH 1018 + LL F +QI GM +L + Sbjct 543 NNNMDSMDTSKLKVHKEHTKLVVNKLYELQGPCETELTPLDLLSFCRQIAMGMEFLASNR 602 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRDLAARNVL+ D+ +KI DFGL++ + E Y+ + +G PV W A E L + Sbjct 603 IVHRDLAARNVLVTEDKTLKIADFGLSRDIYE-ENQYKQKGNGKMPVKWMALESLTRRVY 661 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SDVWSFGV ++E++T + G ++ RL L G R+P+P Sbjct 662 TTQSDVWSFGVVIWEIVT--------------VGGSPYPEVPAARLVRSLRSGYRMPKPV 707 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 C +Y +M+ CW RPTF L L + Sbjct 708 NCSKPLYDIMRACWNASPRDRPTFPELHQKLDDL 741 Score = 206 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 62/358 (17%), Positives = 109/358 (30%), Gaps = 90/358 (25%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S V + +G+G V G L G Sbjct 427 SADDHWEVRSDRVLLHEVIGEGAFGVVRRGTLAPGGKS---------------------- 464 Query 637 LRVVLKVLDPS-HHDIALAFYETASLMSQVS-HTHLAFVHGVCVRGPENIMVTEYVEHGP 694 V +K+L + +F LM V H H+ + G C G + ++V EY G Sbjct 465 --VAVKMLKEFPSQEEVRSFRSEMELMKSVGAHPHVVSLVGCCS-GRKPLIVAEYCSRGD 521 Query 695 LDVWLRRE----------------------------------------------RGHVPM 708 L +LR + Sbjct 522 LLSYLRSSWDIIVSKHTAKYYNNNMDSMDTSKLKVHKEHTKLVVNKLYELQGPCETELTP 581 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + +Q+A + +L + +VH ++ RN+L+ +K++D G+ Sbjct 582 LDLLSFCRQIAMGMEFLASNRIVHRDLAARNVLVTE-------DKTLKIADFGLSRDIYE 634 Query 769 REERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + ++ + W+A E L +T D W FG + EI G +P + Sbjct 635 ENQYKQKGNGKMPVKWMALESLTRRV--YTTQSDVWSFGVVIWEIVTVGGSPYPEVPAAR 692 Query 823 KEHFYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + +R+P+ L + C P RP+F + + L L A+ Sbjct 693 LVRSLRSGYRMPKPVNCSKPLYDIMRACWNASPRDRPTFPELHQKLDDLLHSACANEY 750 >sp|Q25410|MIPR_LYMST Putative molluscan insulin-related peptide(s) receptor OS=Lymnaea stagnalis OX=6523 PE=2 SV=1 Length=1607 Score = 263 bits (671), Expect = 2e-70, Method: Composition-based stats. Identities = 92/313 (29%), Positives = 148/313 (47%), Gaps = 29/313 (9%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-- 926 + + + SD + +K I++LG+G FG V D E Sbjct 1009 MTVISRNMNYVPSEILYISDEWEVDRDKIKLIKELGQGSFGMVYEGVAKGIRDDPNEEIP 1068 Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VAVK + R + +E ++ + H++K G + ++ME + LG L Sbjct 1069 VAVKTVNDRASFSDRREFLKEATTMKEFHCHHVVKLLGVVSTG--QPALVIMELMALGDL 1126 Query 987 RDYLPRHSIGLAQ----------LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036 ++YL H +L A +I +GMAYL + ++HRDLAARN ++ +R Sbjct 1127 KNYLRGHRPDEDHPGVMPPHLLDILQMAGEIADGMAYLADKKFVHRDLAARNCMVSEERT 1186 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 VKIGDFG+ + + E +YYR G PV W APE LK+ F SDVWS+GV ++E++T Sbjct 1187 VKIGDFGMTRDIYE-TDYYRKGGKGMLPVRWMAPESLKDGVFTSLSDVWSYGVVMWEMVT 1245 Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156 L ++ + + + G + P+ CP E+ +LM++CW + Sbjct 1246 --------------LAAQPYQGLSNEEVVKFISDGYIMELPENCPNEMAYLMQHCWAKKP 1291 Query 1157 SFRPTFENLIPIL 1169 + RPTF+ +I L Sbjct 1292 NQRPTFKAIIEYL 1304 Score = 246 bits (628), Expect = 4e-65, Method: Composition-based stats. Identities = 69/325 (21%), Positives = 127/325 (39%), Gaps = 44/325 (14%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 + ++ ++ + L VD+ +I + LGQG+ VYEG + Sbjct 1006 SDDMTVISRNMNYVPSEILYISDEWEVDRDKIKLIKELGQGSFGMVYEGVAKGIRD---- 1061 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676 D +E+ V +K + D + F + A+ M + H+ + GV Sbjct 1062 --------------DPNEEIPVAVKTVNDRASFSDRREFLKEATTMKEFHCHHVVKLLGV 1107 Query 677 CVRGPENIMVTEYVEHGPLDVWLRRERGHVP--------MAWKMVVAQQLASALSYLENK 728 G +++ E + G L +LR R + + +A ++A ++YL +K Sbjct 1108 VSTGQPALVIMELMALGDLKNYLRGHRPDEDHPGVMPPHLLDILQMAGEIADGMAYLADK 1167 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPE 782 VH ++ RN +++ +K+ D G+ + + + W+APE Sbjct 1168 KFVHRDLAARNCMVSEE-------RTVKIGDFGMTRDIYETDYYRKGGKGMLPVRWMAPE 1220 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQ 840 L G ++ D W +G + E+ P Q S E F + LPE + Sbjct 1221 SLKDGV--FTSLSDVWSYGVVMWEMVTLAAQPYQGLSNEEVVKFISDGYIMELPENCPNE 1278 Query 841 LATLTSQCLTYEPTQRPSFRTILRD 865 +A L C +P QRP+F+ I+ Sbjct 1279 MAYLMQHCWAKKPNQRPTFKAIIEY 1303 >sp|Q9C5S8|CRK5_ARATH Cysteine-rich receptor-like protein kinase 5 OS=Arabidopsis thaliana OX=3702 GN=CRK5 PE=1 SV=1 Length=659 Score = 252 bits (643), Expect = 3e-70, Method: Composition-based stats. Identities = 75/282 (27%), Positives = 115/282 (41%), Gaps = 18/282 (6%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 LG+G FG+V G VAVK L G Q +K E+ ++ L H + Sbjct 342 MCNKLGQGGFGQVYKGTL-----PNGVQVAVKRLSKTSG-QGEKEFKNEVVVVAKLQHRN 395 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYL 1014 ++K G C ++ EK LV E+V SL +L + + I G+ YL Sbjct 396 LVKLLGFCLEREEK--ILVYEFVSNKSLDYFLFDSRMQSQLDWTTRYKIIGGIARGILYL 453 Query 1015 HAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 H IHRDL A N+LLD D K+ DFG+A+ R + +PE Sbjct 454 HQDSRLTIIHRDLKAGNILLDADMNPKVADFGMARIFEIDQTEAHTRR-VVGTYGYMSPE 512 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLTELLE 1129 +F SDV+SFGV + E+++ +S F L+ + +L++ Sbjct 513 YAMYGQFSMKSDVYSFGVLVLEIISGRKNSSLYQMDASFGNLVTYTWRLWSDGSPLDLVD 572 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 R H+ C + + RPT ++ +L T Sbjct 573 SSFRDSYQRNEIIRCIHIALLCVQEDTENRPTMSAIVQMLTT 614 Score = 231 bits (590), Expect = 3e-63, Method: Composition-based stats. Identities = 58/324 (18%), Positives = 109/324 (34%), Gaps = 65/324 (20%) Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 T Q F ++ + + + LGQG VY+G L Sbjct 322 TAGSLQFDFKVIEAATDKFSMCNKLGQGGFGQVYKGTLPNG------------------- 362 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 ++V +K L + F +++++ H +L + G C+ E I+V E+V Sbjct 363 ------VQVAVKRLSKTSGQGEKEFKNEVVVVAKLQHRNLVKLLGFCLEREEKILVYEFV 416 Query 691 EHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745 + LD +L R + W + + +A + YL + ++H ++ NILL Sbjct 417 SNKSLDYFLFDSRMQSQLDWTTRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNILLD-- 474 Query 746 GLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 K++D G+ V +++PE G S D + Sbjct 475 -----ADMNPKVADFGMARIFEIDQTEAHTRRVVGTYGYMSPEYAMYG--QFSMKSDVYS 527 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------------QL 841 FG +LEI + + + + RL P + Sbjct 528 FGVLVLEIISGRKNSSLYQMDASFGNLVTYTWRLWSDGSPLDLVDSSFRDSYQRNEIIRC 587 Query 842 ATLTSQCLTYEPTQRPSFRTILRD 865 + C+ + RP+ I++ Sbjct 588 IHIALLCVQEDTENRPTMSAIVQM 611 >sp|Q03146|DDR1_MOUSE Epithelial discoidin domain-containing receptor 1 OS=Mus musculus OX=10090 GN=Ddr1 PE=2 SV=2 Length=911 Score = 257 bits (657), Expect = 3e-70, Method: Composition-based stats. Identities = 98/317 (31%), Positives = 143/317 (45%), Gaps = 45/317 (14%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD------------PTNDGTGEMVAVKALKA 934 F + L+ LGEG FG+V L + + G +VAVK L+ Sbjct 598 PPRVDFPRSRLRFKEKLGEGQFGEVHLCEVEDPQDLVSSDFPISVHKGHPLLVAVKILRP 657 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993 D R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L Sbjct 658 DATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSARQ 715 Query 994 -------------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034 +I LL QI GM YL +++HRDLA RN L+ + Sbjct 716 LENKATQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLVGEN 775 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 +KI DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+ Sbjct 776 FTIKIADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEV 834 Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER--LPRPDKCPCEVYHLMKNCW 1152 L C +S P L + + R ++G + L RP CP +Y LM CW Sbjct 835 LMLC---RSQPFGQLTDEQVIENAGEFFR-----DQGRQVYLSRPPACPQTLYELMLRCW 886 Query 1153 ETEASFRPTFENLIPIL 1169 E RP F L L Sbjct 887 SREPEQRPPFAQLHRFL 903 Score = 231 bits (588), Expect = 2e-61, Method: Composition-based stats. Identities = 74/316 (23%), Positives = 123/316 (39%), Gaps = 52/316 (16%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + + LG+G V+ + E+ + +G L V +K+L Sbjct 604 PRSRLRFKEKLGEGQFGEVH--------LCEVEDPQDLVSSDFPISVHKGHPLLVAVKIL 655 Query 645 DPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---- 699 P A F + +MS++ ++ + GVCV+ M+T+Y+E+G L+ +L Sbjct 656 RPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSARQ 715 Query 700 --------------RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 + + + V Q+AS + YL N VH ++ RN L+ Sbjct 716 LENKATQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLV--- 772 Query 746 GLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWG 799 G + IK++D G+ + + V I W+A EC+ G +TA D W Sbjct 773 ----GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG--KFTTASDVWA 826 Query 800 FGATLLEI-CFDGEAPLQSRSPSEKE----HFYQRQHRL-----PEPSCPQLATLTSQCL 849 FG TL E+ P + + F++ Q R P L L +C Sbjct 827 FGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQTLYELMLRCW 886 Query 850 TYEPTQRPSFRTILRD 865 + EP QRP F + R Sbjct 887 SREPEQRPPFAQLHRF 902 >sp|Q9SYS3|CRK40_ARATH Cysteine-rich receptor-like protein kinase 40 OS=Arabidopsis thaliana OX=3702 GN=CRK40 PE=2 SV=1 Length=654 Score = 252 bits (643), Expect = 3e-70, Method: Composition-based stats. Identities = 77/305 (25%), Positives = 121/305 (40%), Gaps = 24/305 (8%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933 +D V LG+G FG V + G+ VAVK L Sbjct 325 YSDSDGQFMLRFDLGMIVMATDDFSSENTLGQGGFGTVYKGTF-----PNGQEVAVKRLT 379 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--- 990 G Q +K E+ +L L H++++K G C + E+ LV E+VP SL ++ Sbjct 380 KGSG-QGDMEFKNEVSLLTRLQHKNLVKLLGFCNEGDEE--ILVYEFVPNSSLDHFIFDE 436 Query 991 -PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 R + + I G+ YLH IHRDL A N+LLD + K+ DFG A+ Sbjct 437 DKRSLLTWEVRFRIIEGIARGLLYLHEDSQLKIIHRDLKASNILLDAEMNPKVADFGTAR 496 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD--SSQSP 1104 + + APE L + SDV+SFGV L E+++ S + Sbjct 497 LFDSDETRAETKRIA-GTRGYMAPEYLNHGQISAKSDVYSFGVMLLEMISGERNNSFEGE 555 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 +G+ ++ L+E P ++ + C + ++ RPT + Sbjct 556 GLAAFAWKRWVEGKPEIIIDPFLIEN------PRNEIIKLIQIGLLCVQENSTKRPTMSS 609 Query 1165 LIPIL 1169 +I L Sbjct 610 VIIWL 614 Score = 239 bits (609), Expect = 8e-66, Method: Composition-based stats. Identities = 63/305 (21%), Positives = 106/305 (35%), Gaps = 57/305 (19%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + + + + LGQG VY+G V +K Sbjct 343 MATDDFSSENTLGQGGFGTVYKGTFPNGQ-------------------------EVAVKR 377 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 L + F SL++++ H +L + G C G E I+V E+V + LD ++ E Sbjct 378 LTKGSGQGDMEFKNEVSLLTRLQHKNLVKLLGFCNEGDEEILVYEFVPNSSLDHFIFDED 437 Query 704 GHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + W + + + +A L YL ++H ++ NILL K++ Sbjct 438 KRSLLTWEVRFRIIEGIARGLLYLHEDSQLKIIHRDLKASNILLD-------AEMNPKVA 490 Query 759 DPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 D G S E R ++APE L G +S D + FG LLE+ Sbjct 491 DFGTARLFDSDETRAETKRIAGTRGYMAPEYLNHG--QISAKSDVYSFGVMLLEMISGER 548 Query 813 ----------APLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860 A R K + P +L + C+ T+RP+ Sbjct 549 NNSFEGEGLAAFAWKRWVEGKPEIIIDPFLIENPRNEIIKLIQIGLLCVQENSTKRPTMS 608 Query 861 TILRD 865 +++ Sbjct 609 SVIIW 613 >sp|P0C5E2|LRL12_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 1.2 OS=Arabidopsis thaliana OX=3702 GN=LRK10L-1.2 PE=2 SV=3 Length=651 Score = 251 bits (642), Expect = 3e-70, Method: Composition-based stats. Identities = 78/313 (25%), Positives = 131/313 (42%), Gaps = 18/313 (6%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 + + ++LG+G FG V G VAVK L D + Sbjct 327 HIFSYEELEEATNNFDPSKELGDGGFGTVYYGKLK-----DGRSVAVKRL-YDNNFKRAE 380 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGL 997 ++ E++IL L H +++ G C + + L LV EYV G+L D+L S+ Sbjct 381 QFRNEVEILTGLRHPNLVALFG-CSSKQSRDLLLVYEYVANGTLADHLHGPQANPSSLPW 439 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + L A + + YLHA IHRD+ + N+LLD + VK+ DFGL++ P + Sbjct 440 SIRLKIAVETASALKYLHASKIIHRDVKSNNILLDQNFNVKVADFGLSRLFPMDKTHVST 499 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQ 1116 G + P+ Y+ SDV+SF V L EL++ + + P + + L +A Sbjct 500 APQG--TPGYVDPDYHLCYQLSNKSDVYSFAVVLMELISSLPAVDITRPRQEINLSNMAV 557 Query 1117 GQMTVLRLTELLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 ++ L ++++ R + V L C +++ RP ++ L + Sbjct 558 VKIQNHELRDMVDPSLGFDTDTRVRQTVIAVAELAFQCLQSDKDLRPCMSHVQDTLTRIQ 617 Query 1174 EKYQGQAPSVFSV 1186 G V V Sbjct 618 NNGFGSEMDVVDV 630 Score = 219 bits (557), Expect = 6e-59, Method: Composition-based stats. Identities = 69/358 (19%), Positives = 121/358 (34%), Gaps = 63/358 (18%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 +++ LG G VY G+L+ S Sbjct 326 VHIFSYEELEEATNNFDPSKELGDGGFGTVYYGKLKDGRS-------------------- 365 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEH 692 V +K L ++ A F +++ + H +L + G + + ++V EYV + Sbjct 366 -----VAVKRLYDNNFKRAEQFRNEVEILTGLRHPNLVALFGCSSKQSRDLLLVYEYVAN 420 Query 693 GPLDVWLRR---ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 G L L +P + ++ +A + ASAL YL ++H +V NILL + Sbjct 421 GTLADHLHGPQANPSSLPWSIRLKIAVETASALKYLHASKIIHRDVKSNNILLDQ----- 475 Query 750 GTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 + +K++D G+ + V ++ P+ LS D + F L Sbjct 476 --NFNVKVADFGLSRLFPMDKTHVSTAPQGTPGYVDPDY--HLCYQLSNKSDVYSFAVVL 531 Query 805 LEICF-----DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL---------------ATL 844 +E+ D P Q + S + H L + P L A L Sbjct 532 MELISSLPAVDITRPRQEINLSNMAVVKIQNHELRDMVDPSLGFDTDTRVRQTVIAVAEL 591 Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902 QCL + RP + LTR+Q + + V + + + D Sbjct 592 AFQCLQSDKDLRPCMSHVQDTLTRIQNNGFGSEMDVVDVNKSGPLVAQSPDSVIVKWD 649 >sp|Q9FID9|Y5389_ARATH Probable receptor-like protein kinase At5g38990 OS=Arabidopsis thaliana OX=3702 GN=At5g38990 PE=2 SV=1 Length=880 Score = 256 bits (655), Expect = 3e-70, Method: Composition-based stats. Identities = 81/347 (23%), Positives = 140/347 (40%), Gaps = 20/347 (6%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 T +P+ S+ +L + + + + + ++ +G G FG Sbjct 478 TNKPSTNSSWGPLLHGTGSTNTKSASSLPSDLCRRFSIYEIKSATNDFEEKLIIGVGGFG 537 Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 V Y DG +VAVK L+ Q + E+++L L H H++ G C+D Sbjct 538 SV----YKGRIDGGATLVAVKRLEI-TSNQGAKEFDTELEMLSKLRHVHLVSLIGYCDDD 592 Query 970 GEKSLQLVMEYVPLGSLRDYLPRH------SIGLAQLLLFAQQICEGMAYLHAQH---YI 1020 E + LV EY+P G+L+D+L R + + L G+ YLH I Sbjct 593 NE--MVLVYEYMPHGTLKDHLFRRDKASDPPLSWKRRLEICIGAARGLQYLHTGAKYTII 650 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ N+LLD + + K+ DFGL++ P V + PE + Sbjct 651 HRDIKTTNILLDENFVAKVSDFGLSRVGPTSASQTHVSTVVKGTFGYLDPEYYRRQILTE 710 Query 1081 ASDVWSFGVTLYELL-THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SDV+SFGV L E+L QS P + +LI + + ++++ Sbjct 711 KSDVYSFGVVLLEVLCCRPIRMQSVPPEQADLIRWVKSNFNKRTVDQIIDSDLTADITST 770 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILK---TVHEKYQGQAPSV 1183 + + C + RP +++ L+ +HE + + +V Sbjct 771 SMEKFCEIAIRCVQDRGMERPPMNDVVWALEFALQLHETAKKKNDNV 817 Score = 224 bits (571), Expect = 2e-59, Method: Composition-based stats. Identities = 69/382 (18%), Positives = 133/382 (35%), Gaps = 53/382 (14%) Query 564 MRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 + A + P L + S + + + + +G G +VY+GR+ Sbjct 499 TKSASSLPSDL-CRRFSIYEIKSATNDFEEKLIIGVGGFGSVYKGRI------------- 544 Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 G V +K L+ + + A F ++S++ H HL + G C Sbjct 545 -----------DGGATLVAVKRLEITSNQGAKEFDTELEMLSKLRHVHLVSLIGYCDDDN 593 Query 682 ENIMVTEYVEHGPLDVWLRRERG--HVPMAW--KMVVAQQLASALSYLE---NKNLVHGN 734 E ++V EY+ HG L L R P++W ++ + A L YL ++H + Sbjct 594 EMVLVYEYMPHGTLKDHLFRRDKASDPPLSWKRRLEICIGAARGLQYLHTGAKYTIIHRD 653 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-------ERIPWLAPECLPGG 787 + NILL + K+SD G+ + + +L PE Sbjct 654 IKTTNILLDE-------NFVAKVSDFGLSRVGPTSASQTHVSTVVKGTFGYLDPEYYRRQ 706 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLT 845 L+ D + FG LLE+ +QS P + + + + + Q+ + LT Sbjct 707 I--LTEKSDVYSFGVVLLEVLCCRPIRMQSVPPEQADLIRWVKSNFNKRTVDQIIDSDLT 764 Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLAD-VLTVNPDSPASDPTVFHKRYLKKIRDLG 904 + + + ++ + D V + + ++ + + Sbjct 765 ADITSTSMEKFCEIAIRCVQDRGMERPPMNDVVWALEFALQLHETAKKKNDNVESLDLMP 824 Query 905 EGHFGKVSLYCYDPTNDGTGEM 926 G G + D + TG + Sbjct 825 SGEVGTTTDGEDDLFSRTTGHV 846 >sp|H2KZU7|SVH2_CAEEL Tyrosine-protein kinase receptor svh-2 OS=Caenorhabditis elegans OX=6239 GN=svh-2 PE=1 SV=1 Length=1086 Score = 259 bits (662), Expect = 3e-70, Method: Composition-based stats. Identities = 89/279 (32%), Positives = 136/279 (49%), Gaps = 20/279 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+GH+G V Y P+ E V K LK S + +E + H +I+K Sbjct 741 IGQGHYGVVYKAMYSPS-KSLEEKVVCKYLK----EGKISEFYEEARTMSEFDHPNILKL 795 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G D ++ EY+ G L+ ++ ++I + L FA I +GM Y+H++ +I Sbjct 796 IGVALDDSSHLPIIITEYMAKGDLKSFIENVENTIKMRDLFEFAFDIAKGMNYMHSKKFI 855 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLA RN LLD VKI DFGL + V E Y + D PV W+ PE + E F Sbjct 856 HRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERDLPVRWFPPE-ISEQGFGI 914 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SD+WSFGV ++EL T + S ++ ++ + T RL +P C Sbjct 915 TSDIWSFGVVIWELFTRGSTPYSNMASWILILPWLKESETN-----------RLRKPPYC 963 Query 1141 PCEVY-HLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P ++Y +M CW+ + RP F +L+ I+ V + +G Sbjct 964 PEKLYTDVMLACWKANPAERPQFSDLVTIIPNVVKYMEG 1002 Score = 212 bits (539), Expect = 9e-55, Method: Composition-based stats. Identities = 63/315 (20%), Positives = 113/315 (36%), Gaps = 51/315 (16%) Query 583 RVDQKEIT--QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 +VD K + +L +GQG VY+ + E +VV Sbjct 727 KVDFKNLRVDKLDPIGQGHYGVVYKAM---------------------YSPSKSLEEKVV 765 Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI--MVTEYVEHGPLDVW 698 K L FYE A MS+ H ++ + GV + ++ ++TEY+ G L + Sbjct 766 CKYLKEGK---ISEFYEEARTMSEFDHPNILKLIGVALDDSSHLPIIITEYMAKGDLKSF 822 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + + M A +A ++Y+ +K +H ++ RN LL +K++ Sbjct 823 IENVENTIKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDE-------HLRVKIA 875 Query 759 DPGVGLGA-------LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 D G+ + ER + W PE G D W FG + E+ G Sbjct 876 DFGLCRKVDIETELYVQMHERDLPVRWFPPEISEQG---FGITSDIWSFGVVIWELFTRG 932 Query 812 EAPLQSRSPSEKEHFYQR-----QHRLPEPSCPQLAT-LTSQCLTYEPTQRPSFRTILRD 865 P + + + + + R P +L T + C P +RP F ++ Sbjct 933 STPYSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACWKANPAERPQFSDLVTI 992 Query 866 LTRLQPHNLADVLTV 880 + + + + Sbjct 993 IPNVVKYMEGYDRSQ 1007 >sp|D7UPN3|RLK10_ORYSJ LysM domain receptor-like kinase 10 OS=Oryza sativa subsp. japonica OX=39947 GN=RLK10 PE=2 SV=1 Length=605 Score = 250 bits (639), Expect = 3e-70, Method: Composition-based stats. Identities = 74/342 (22%), Positives = 125/342 (37%), Gaps = 28/342 (8%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 + + + + + + + + + Sbjct 265 IMFYRWQKFRKATSRPSPEETSHLDDASQAEGIKVERSIEFSYEEIFNATQGFSME-HKI 323 Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963 G+G FG V GE A+K + G Q + E+ +L ++H ++++ Sbjct 324 GQGGFGSVYYAELR------GEKTAIKKM----GMQATQEFLAELKVLTHVHHLNLVRLI 373 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQHY- 1019 G C E L LV E++ G+L +L R + A + A G+ YLH Sbjct 374 GYCV---ENCLFLVYEFIDNGNLSQHLQRTGYAPLSWATRVQIALDSARGLEYLHEHVVP 430 Query 1020 --IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRD+ + N+LLD D KI DFGLAK G + + PE + + Sbjct 431 VYVHRDIKSANILLDKDFRAKIADFGLAKLTEVGSMSQSLSTRVAGTFGYMPPE-ARYGE 489 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA-------QGQMTVLRLTELLER 1130 DV++FGV LYELL+ + E G+ L EL++ Sbjct 490 VSPKVDVYAFGVVLYELLSAKQAIVRSSESVSESKGLVFLFEEALSAPNPTEALDELIDP 549 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + P ++ L K+C E RPT +++ L + Sbjct 550 SLQGDYPVDSALKIASLAKSCTHEEPGMRPTMRSVVVALMAL 591 Score = 197 bits (502), Expect = 4e-52, Method: Composition-based stats. Identities = 76/368 (21%), Positives = 133/368 (36%), Gaps = 79/368 (21%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRV 610 P P ETS+L A ++ + S+ + + + +GQG +VY LR Sbjct 280 PSPEETSHLDDASQAEGIKVERSI-EFSYEEIFNATQGFSMEHKIGQGGFGSVYYAELRG 338 Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670 E + +K + F +++ V H +L Sbjct 339 EKT--------------------------AIKKM---GMQATQEFLAELKVLTHVHHLNL 369 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK 728 + G CV +V E++++G L L+R G+ P++W ++ +A A L YL Sbjct 370 VRLIGYCVE-NCLFLVYEFIDNGNLSQHLQRT-GYAPLSWATRVQIALDSARGLEYLHEH 427 Query 729 NL---VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSRE---ERVERIPW 778 + VH ++ NILL + A K++D G+ G++S+ + Sbjct 428 VVPVYVHRDIKSANILLDKDFRA-------KIADFGLAKLTEVGSMSQSLSTRVAGTFGY 480 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP-----------SEKEHFY 827 + PE +S +D + FG L E+ +A ++S E Sbjct 481 MPPEA---RYGEVSPKVDVYAFGVVLYELLSAKQAIVRSSESVSESKGLVFLFEEALSAP 537 Query 828 QRQHRLPEPSCPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 L E P L A+L C EP RP+ R+++ L L + Sbjct 538 NPTEALDELIDPSLQGDYPVDSALKIASLAKSCTHEEPGMRPTMRSVVVALMALTANTDL 597 Query 876 DVLTVNPD 883 + +P Sbjct 598 RDMDYHPF 605 >sp|Q9Z139|ROR1_MOUSE Inactive tyrosine-protein kinase transmembrane receptor ROR1 OS=Mus musculus OX=10090 GN=Ror1 PE=2 SV=2 Length=937 Score = 257 bits (657), Expect = 3e-70, Method: Composition-based stats. Identities = 82/291 (28%), Positives = 135/291 (46%), Gaps = 35/291 (12%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 + +LGE FGK+ ++VA+K LK PQ + ++QE ++ L+H + Sbjct 475 FMEELGECTFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPN 534 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------------------RHSIGLAQL 1000 I+ G E+ + ++ EY+ G L ++L + S+ Sbjct 535 IVCLLGAVTQ--EQPVCMLFEYMNQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDF 592 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 L A QI GM YL + ++H+DLAARN+L+ VKI D GL++ + +YYRV+ Sbjct 593 LHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIY-SADYYRVQSK 651 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 P+ W PE + KF SD+WSFGV L+E+ + + Sbjct 652 SSLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQ--------------PYYGFS 697 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + E++ + + LP + CP +Y LM CW S RP F+++ L++ Sbjct 698 NQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRS 748 Score = 243 bits (620), Expect = 2e-65, Method: Composition-based stats. Identities = 74/340 (22%), Positives = 129/340 (38%), Gaps = 62/340 (18%) Query 549 RCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRL 608 R P G+ + ++ + + + + + LG+ T +Y+G L Sbjct 441 RQPKPVRGQNVEMSMLNAYKPKSKA--------KELPLSAVRFMEELGECTFGKIYKGHL 492 Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSH 667 +PG D Q V +K L ++ F + ASLM+++ H Sbjct 493 ------------------YLPGMDHAQ--LVAIKTLKDYNNPQQWTEFQQEASLMAELHH 532 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK---------------- 711 ++ + G + M+ EY+ G L +L H + Sbjct 533 PNIVCLLGAVTQEQPVCMLFEYMNQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDF 592 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771 + +A Q+A+ + YL + VH ++ RNIL+ G +K+SD G+ S + Sbjct 593 LHIAIQIAAGMEYLSSHFFVHKDLAARNILI-------GEQLHVKISDLGLSREIYSADY 645 Query 772 RVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 I W+ PE + G S+ D W FG L EI G P S E Sbjct 646 YRVQSKSSLPIRWMPPEAIMYG--KFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIE 703 Query 826 FYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTIL 863 +++ LP P++ +L ++C P++RP F+ I Sbjct 704 MVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIH 743 >sp|P00534|ERBB_ALV Tyrosine-protein kinase transforming protein erbB OS=Avian leukosis virus OX=11864 GN=V-ERBB PE=2 SV=2 Length=634 Score = 251 bits (640), Expect = 4e-70, Method: Composition-based stats. Identities = 91/272 (33%), Positives = 134/272 (49%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + VA+K L+ P+ E ++ ++ + H+ + Sbjct 138 LGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRL 197 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C +QL+ + +P G L DY+ H IG LL + QI +GM YL + + Sbjct 198 LGICLTST---VQLITQLMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLV 254 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ + VKI DFGLAK + + Y E G P+ W A E + + + Sbjct 255 HRDLAARNVLVKTPQHVKITDFGLAKLLGADEKEYHA-EGGKVPIKWMALESILHRIYTH 313 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + ++ +LE+GERLP+P C Sbjct 314 QSDVWSYGVTVWELMTFGSK--------------PYDGIPASEISSVLEKGERLPQPPIC 359 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW +A RP F LI + Sbjct 360 TIDVYMIMVKCWMIDADSRPKFRELIAEFSKM 391 Score = 226 bits (575), Expect = 2e-61, Method: Composition-based stats. Identities = 68/345 (20%), Positives = 136/345 (39%), Gaps = 39/345 (11%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P +Q + + E ++ LG G VY+G EG Sbjct 113 TPSGEAPNQAHLRILKETEFKKVKVLGSGAFGTVYKGLWIPEGEKV-------------- 158 Query 630 GRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ V +K L + + A +M+ V + H+ + G+C+ ++T+ Sbjct 159 ------KIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQ-LITQ 211 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + +G L ++R + ++ + + Q+A ++YLE + LVH ++ RN+L+ Sbjct 212 LMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLVHRDLAARNVLV------ 265 Query 749 EGTSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGA 802 T +K++D G+ LGA +E E I W+A E + + D W +G Sbjct 266 -KTPQHVKITDFGLAKLLGADEKEYHAEGGKVPIKWMALESILHRI--YTHQSDVWSYGV 322 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860 T+ E+ G P SE ++ RLP+P + + +C + RP FR Sbjct 323 TVWELMTFGSKPYDGIPASEISSVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFR 382 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 ++ + +++ ++ + K Y + + Sbjct 383 ELIAEFSKMARDPPRYLVIQGDERMHLPSPTDSKFYRTLMEEEDM 427 >sp|O64778|Y1142_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61420 OS=Arabidopsis thaliana OX=3702 GN=At1g61420 PE=3 SV=2 Length=807 Score = 255 bits (651), Expect = 4e-70, Method: Composition-based stats. Identities = 81/308 (26%), Positives = 126/308 (41%), Gaps = 17/308 (6%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 D LG+G FG V G+ +AVK L + G Q + Sbjct 480 DFFDMHTIQTATNNFSISNKLGQGGFGPVYKGKLQ-----DGKEIAVKRLSSSSG-QGKE 533 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLA 998 + EI ++ L H+++++ GCC + EK L+ E++ SL +L R I Sbjct 534 EFMNEIVLISKLQHKNLVRILGCCIEGEEK--LLIYEFMLNNSLDTFLFDSRKRLEIDWP 591 Query 999 QLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + L Q I G+ YLH IHRDL N+LLD KI DFGLA+ + +G EY Sbjct 592 KRLDIIQGIARGIHYLHRDSHLKVIHRDLKVSNILLDEKMNPKISDFGLAR-MYQGTEYQ 650 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGI 1114 + + APE F SD++SFGV + E+++ S S + LI Sbjct 651 DNTRRVVGTLGYMAPEYAWTGMFSEKSDIYSFGVLMLEIISGEKISRFSYGKEEKTLIAY 710 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 A +LL++ + C + + + RP L+ +L T + Sbjct 711 AWESWCDTGGIDLLDKDVADSCRPLEVERCVQIGLLCVQHQPADRPNTLELLSMLTTTSD 770 Query 1175 KYQGQAPS 1182 + P+ Sbjct 771 LPPPEQPT 778 Score = 236 bits (602), Expect = 9e-64, Method: Composition-based stats. Identities = 56/261 (21%), Positives = 99/261 (38%), Gaps = 45/261 (17%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L+ + + + + LGQG VY+G+L+ Sbjct 479 LDFFDMHTIQTATNNFSISNKLGQGGFGPVYKGKLQDGK--------------------- 517 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + +K L S F L+S++ H +L + G C+ G E +++ E++ + Sbjct 518 ----EIAVKRLSSSSGQGKEEFMNEIVLISKLQHKNLVRILGCCIEGEEKLLIYEFMLNN 573 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748 LD +L R + + W ++ + Q +A + YL ++H ++ NILL Sbjct 574 SLDTFLFDSRKRLEIDWPKRLDIIQGIARGIHYLHRDSHLKVIHRDLKVSNILLDEK--- 630 Query 749 EGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGA 802 K+SD G+ E + V + ++APE G S D + FG Sbjct 631 ----MNPKISDFGLARMYQGTEYQDNTRRVVGTLGYMAPEYAWTGM--FSEKSDIYSFGV 684 Query 803 TLLEICFDGEAPLQSRSPSEK 823 +LEI + S EK Sbjct 685 LMLEIISGEKISRFSYGKEEK 705 >sp|O22040|ANP1_ARATH Mitogen-activated protein kinase kinase kinase ANP1 OS=Arabidopsis thaliana OX=3702 GN=ANP1 PE=1 SV=2 Length=666 Score = 251 bits (642), Expect = 4e-70, Method: Composition-based stats. Identities = 71/308 (23%), Positives = 137/308 (44%), Gaps = 28/308 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 ++ + + +P PA+ + +K + +G G FG V + N +GE++ Sbjct 40 CIRKSKIFIKPSFSPPPPANTVDMAPPISWRKGQLIGRGAFGTVYMGM----NLDSGELL 95 Query 928 AVKAL-------KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 AVK + + H ++E+ +L+ L H +I++Y G + + +L +++E+ Sbjct 96 AVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNIVRYLGTVRE--DDTLNILLEF 153 Query 981 VPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 VP GS+ L + + + + +Q+ G+ YLH +HRD+ N+L+DN +K+ Sbjct 154 VPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHAIMHRDIKGANILVDNKGCIKL 213 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFG +K V E + +P +W APE + + +++D+WS G T+ E++T Sbjct 214 ADFGASKQVAELATMTGAKSMKGTP-YWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKA 272 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 +Q V + + P PD + + C + + R Sbjct 273 P-------------WSQQYKEVAAIFFIGTTKSHPPIPDTLSSDAKDFLLKCLQEVPNLR 319 Query 1160 PTFENLIP 1167 PT L+ Sbjct 320 PTASELLK 327 Score = 199 bits (506), Expect = 3e-52, Method: Composition-based stats. Identities = 57/293 (19%), Positives = 99/293 (34%), Gaps = 37/293 (13%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 + +G+G VY G G + + + + + Sbjct 70 RKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAH-------------- 115 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 E L+ +SH ++ G ++ E+V G + L + G P + Sbjct 116 --IQELEEEVKLLKNLSHPNIVRYLGTVREDDTLNILLEFVPGGSISSLL-EKFGPFPES 172 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA--- 766 +QL L YL N ++H ++ G NIL+ G IKL+D G Sbjct 173 VVRTYTRQLLLGLEYLHNHAIMHRDIKGANILVDNKG-------CIKLADFGASKQVAEL 225 Query 767 ---LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + W+APE + +S S D W G T++E+ G+AP + Sbjct 226 ATMTGAKSMKGTPYWMAPEVILQTGHSFS--ADIWSVGCTVIEMV-TGKAPWSQQYKEVA 282 Query 824 EHFYQ----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 F+ +P+ +CL P RP+ +L+ + H Sbjct 283 AIFFIGTTKSHPPIPDTLSSDAKDFLLKCLQEVPNLRPTASELLKHPFVMGKH 335 >sp|P06213|INSR_HUMAN Insulin receptor OS=Homo sapiens OX=9606 GN=INSR PE=1 SV=4 Length=1382 Score = 261 bits (667), Expect = 4e-70, Method: Composition-based stats. Identities = 94/304 (31%), Positives = 148/304 (49%), Gaps = 29/304 (10%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGP 938 D + + +R+LG+G FG V G E VAVK + Sbjct 1006 FPCSVYVPDEWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASL 1065 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------- 991 + R + E +++ H+++ G +G+ +L +VME + G L+ YL Sbjct 1066 RERIEFLNEASVMKGFTCHHVVRLLGVV-SKGQPTL-VVMELMAHGDLKSYLRSLRPEAE 1123 Query 992 ----RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 R L +++ A +I +GMAYL+A+ ++HRDLAARN ++ +D VKIGDFG+ + Sbjct 1124 NNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRD 1183 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + E +YYR G PV W APE LK+ F +SD+WSFGV L+E+ + Sbjct 1184 IYE-TDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITS----------- 1231 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L ++ ++ + + G L +PD CP V LM+ CW+ RPTF ++ Sbjct 1232 ---LAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVN 1288 Query 1168 ILKT 1171 +LK Sbjct 1289 LLKD 1292 Score = 251 bits (642), Expect = 5e-67, Method: Composition-based stats. Identities = 100/519 (19%), Positives = 183/519 (35%), Gaps = 82/519 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPF----VQAKLRPED----GLYLIHW-STSHPYRLILTVA 488 V+ + + D I GP+ V + E GL +++ S L + Sbjct 840 VSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLC 899 Query 489 QRSQAPDGMQSLRLRKFPIEQ-----------------QDGAFVLEGWGRSFPSVREL-- 529 + + RLR + F + + ++ ++ Sbjct 900 VSRKHFALERGCRLRGLSPGNYSVRIRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIII 959 Query 530 --GAALQGCLLRAGDDCFSLRRCCLPQPGE----TSNLIIMRGARASPRTLNLSQLSFHR 583 + + G LR+ P +SN + + P ++ + Sbjct 960 GPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVP--DEWE 1017 Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +++IT L LGQG+ VYEG R G+ E RV +K Sbjct 1018 VSREKITLLRELGQGSFGMVYEGNARDIIKGEA-------------------ETRVAVKT 1058 Query 644 LDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR- 701 ++ S + F AS+M + H+ + GV +G ++V E + HG L +LR Sbjct 1059 VNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSL 1118 Query 702 --------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 R + + +A ++A ++YL K VH ++ RN ++A Sbjct 1119 RPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAH-------DF 1171 Query 754 FIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+ D G+ + + + W+APE L G +T+ D W FG L EI Sbjct 1172 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGV--FTTSSDMWSFGVVLWEI 1229 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 E P Q S + F L P+ ++ L C + P RP+F I+ Sbjct 1230 TSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNL 1289 Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 L + +V + + + + + + + ++ Sbjct 1290 LKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMENVP 1328 >sp|Q55A09|Y9963_DICDI Probable serine/threonine-protein kinase DDB_G0272254 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0272254 PE=3 SV=1 Length=1331 Score = 261 bits (666), Expect = 4e-70, Method: Composition-based stats. Identities = 78/293 (27%), Positives = 129/293 (44%), Gaps = 42/293 (14%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL---KADCGPQHRSGWKQE 947 + + +K +++G+GHF KV + G+ VAVK L K + +K E Sbjct 1067 MINYSDIKIDKEIGKGHFSKVLKGNWK------GKDVAVKKLNSNKDKAREEMIQEFKAE 1120 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--------SIGLAQ 999 +++L +L H +++ G + +VME++P G+L + + + Sbjct 1121 VELLGSLQHPNLVTCYGYSL----NPMCIVMEFLPSGNLFELIHSKPSEQQQSIKLDSTL 1176 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 +L A I GM +LH ++ IHRDL + N+L+D +KI D G+A+ + Sbjct 1177 ILAIAFDIARGMQHLHTRNIIHRDLKSSNLLMDKHFNIKIADLGIAR-----ETSFTQTM 1231 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQ 1118 V W APE L+ + +DV+S+ + LYELLT + Q PP L+ Sbjct 1232 TTIGTVAWTAPEILRHESYNQKADVYSYAIVLYELLTGEEPYQGIPPMNAGILVA----- 1286 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +G R PD C L+ CW + + RP+FE + L Sbjct 1287 ----------SKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITNYLTK 1329 Score = 221 bits (563), Expect = 2e-57, Method: Composition-based stats. Identities = 55/301 (18%), Positives = 106/301 (35%), Gaps = 53/301 (18%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 S ++ +I +G+G + V +G + + V Sbjct 1064 SVTMINYSDIKIDKEIGKGHFSKVLKGNWKGKD--------------------------V 1097 Query 640 VLKVL----DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 +K L D + ++ F L+ + H +L +G + +V E++ G L Sbjct 1098 AVKKLNSNKDKAREEMIQEFKAEVELLGSLQHPNLVTCYGYSL--NPMCIVMEFLPSGNL 1155 Query 696 DVWLRRERG------HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 + + + + +A +A + +L +N++H ++ N+L+ + Sbjct 1156 FELIHSKPSEQQQSIKLDSTLILAIAFDIARGMQHLHTRNIIHRDLKSSNLLMDK----- 1210 Query 750 GTSPFIKLSDPGVGL--GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 IK++D G+ + + W APE L S + D + + L E+ Sbjct 1211 --HFNIKIADLGIARETSFTQTMTTIGTVAWTAPEILRH--ESYNQKADVYSYAIVLYEL 1266 Query 808 CFDGEAPLQSRSPSEKEHFYQR---QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 GE P Q P + LP+ P L C + +P +RPSF I Sbjct 1267 L-TGEEPYQGIPPMNAGILVASKGLRPELPDNCDPNWKKLVVWCWSEDPNKRPSFEEITN 1325 Query 865 D 865 Sbjct 1326 Y 1326 >sp|Q02779|M3K10_HUMAN Mitogen-activated protein kinase kinase kinase 10 OS=Homo sapiens OX=9606 GN=MAP3K10 PE=1 SV=3 Length=954 Score = 257 bits (657), Expect = 5e-70, Method: Composition-based stats. Identities = 93/341 (27%), Positives = 138/341 (40%), Gaps = 41/341 (12%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 + + + P N + P L+ +G G FGKV Sbjct 56 EGWWTGQLPSGRVGVFPSNYVAPGAPAAPAGLQLPQEIPFHELQLEEIIGVGGFGKVYRA 115 Query 915 CYDPTNDGTGEMVAVK--ALKADCGPQHR-SGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 + GE VAVK L + P QE + L H +II +G C + Sbjct 116 LWR------GEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRGACLNP-- 167 Query 972 KSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028 L LVMEY G+L L + L+ +A Q+ GM YLH IHRDL + N Sbjct 168 PHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSIN 227 Query 1029 VLLDN--------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 +L+ D ++KI DFGLA+ + + W APE ++ F Sbjct 228 ILILEAIENHNLADTVLKITDFGLAR-----EWHKTTKMSAAGTYAWMAPEVIRLSLFSK 282 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 +SDVWSFGV L+ELLT P + ++ + +A G + LP P C Sbjct 283 SSDVWSFGVLLWELLTG-----EVPYREIDALAVAYG---------VAMNKLTLPIPSTC 328 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 P L++ CW+ + RP F +++ L+ + + Q P Sbjct 329 PEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQSALFQMP 369 Score = 221 bits (564), Expect = 4e-58, Method: Composition-based stats. Identities = 80/382 (21%), Positives = 136/382 (36%), Gaps = 44/382 (12%) Query 527 RELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ 586 + L +GD+ + + + G + + GA A+P L L Q + Sbjct 40 GDRVQVLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPGAPAAPAGLQLPQ----EIPF 95 Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 E+ +G G VY R G+E+ V LDP Sbjct 96 HELQLEEIIGVGGFGKVYRALWR------------------------GEEVAVKAARLDP 131 Query 647 SHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 A + A L + H ++ + G C+ P +V EY G L L R Sbjct 132 EKDPAVTAEQVCQEARLFGALQHPNIIALRGACLNPPHLCLVMEYARGGALSRVLAGRR- 190 Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFI-KLSDP 760 VP + A Q+A ++YL N ++H ++ NIL+ + + K++D Sbjct 191 -VPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDF 249 Query 761 GVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 G+ ++ W+APE + + S + D W FG L E+ GE P + Sbjct 250 GLAREWHKTTKMSAAGTYAWMAPEVIR--LSLFSKSSDVWSFGVLLWELL-TGEVPYREI 306 Query 819 SPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + + +P A L +C +P RP F +IL+ L ++ L Sbjct 307 DALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQSALF 366 Query 876 DVLTVNPDSPASDPTVFHKRYL 897 + + S D + + Sbjct 367 QMPLESFHSLQEDWKLEIQHMF 388 >sp|Q7T2V3|M3K10_XENLA Mitogen-activated protein kinase kinase kinase 10 OS=Xenopus laevis OX=8355 GN=map3k10 PE=1 SV=1 Length=1005 Score = 258 bits (658), Expect = 5e-70, Method: Composition-based stats. Identities = 102/403 (25%), Positives = 150/403 (37%), Gaps = 54/403 (13%) Query 795 MDKWGFGAT--LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYE 852 D +G + L FD E P+ +E R+ L E + Sbjct 25 SDVQSYGVSNPLWMAVFDYE-------PTAEEELTLRRGDLVEILSKDSTVSGDEGW--- 74 Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVS 912 + + + P L +G G FGKV Sbjct 75 -WTGKIKDKVGIFPSNYVVSDDKYTTLTGAPKQCPLPLEIEFDELNLDEIIGVGGFGKVY 133 Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHR---SGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 + E VAVKA++ D +QE I L H +II G C Sbjct 134 KGLWR------DEEVAVKAVRHDPDEDINVTAENVRQEAKIFCMLCHPNIIALTGVCLKP 187 Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAA 1026 L LVMEY G L L + L+ +A QI +GM YLH + IHRDL + Sbjct 188 --PHLCLVMEYARGGPLHRALAGKKVPAHVLVNWAVQIAKGMTYLHNEAIVPIIHRDLGS 245 Query 1027 RNVLLDN--------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 N+L+ ++ + I DFGLA+ + + W APE ++ F Sbjct 246 SNILILEKAENDDLFNKTLNITDFGLAREWQK-----TTKMSAAGTYAWMAPEVIRLSLF 300 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 +SDVWSFGV L+ELLT P + ++ + +A G + LP P Sbjct 301 SKSSDVWSFGVLLWELLTG-----EVPYREIDALAVAYG---------VAMNKLTLPIPS 346 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 CP +++ CW+ + RPTF ++ L T+ + Q P Sbjct 347 TCPEPFVRILEACWDPDPHSRPTFSCILEQLTTIEQSAMFQMP 389 Score = 219 bits (559), Expect = 2e-57, Method: Composition-based stats. Identities = 64/328 (20%), Positives = 121/328 (37%), Gaps = 44/328 (13%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 ++ E+ +G G VY+G R E V +K Sbjct 112 EIEFDELNLDEIIGVGGFGKVYKGLWRDE--------------------------EVAVK 145 Query 643 VLDPSHHD----IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 + + A + A + + H ++ + GVC++ P +V EY GPL Sbjct 146 AVRHDPDEDINVTAENVRQEAKIFCMLCHPNIIALTGVCLKPPHLCLVMEYARGGPLHRA 205 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGT-SPF 754 L ++ VP + A Q+A ++YL N+ ++H ++ NIL+ + + Sbjct 206 LAGKK--VPAHVLVNWAVQIAKGMTYLHNEAIVPIIHRDLGSSNILILEKAENDDLFNKT 263 Query 755 IKLSDPGVGL--GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 + ++D G+ ++ W+APE + + S + D W FG L E+ GE Sbjct 264 LNITDFGLAREWQKTTKMSAAGTYAWMAPEVIR--LSLFSKSSDVWSFGVLLWELL-TGE 320 Query 813 APLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 P + + + +P + C +P RP+F IL LT + Sbjct 321 VPYREIDALAVAYGVAMNKLTLPIPSTCPEPFVRILEACWDPDPHSRPTFSCILEQLTTI 380 Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYL 897 + + + + S D + ++ Sbjct 381 EQSAMFQMPLESFHSLQEDWRLEIQQMF 408 >sp|Q9SF86|PCRK1_ARATH Serine/threonine-protein kinase PCRK1 OS=Arabidopsis thaliana OX=3702 GN=PCRK1 PE=1 SV=1 Length=418 Score = 244 bits (622), Expect = 6e-70, Method: Composition-based stats. Identities = 78/288 (27%), Positives = 128/288 (44%), Gaps = 13/288 (5%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG FG V D + ++ VAVK L G Q W E++ L + H +++K Sbjct 90 IGEGGFGCVFRGTVRNLEDSSVKIEVAVKQL-GKRGLQGHKEWVTEVNFLGIVEHTNLVK 148 Query 962 YKGCCEDQGEKSL--QLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAYLHA 1016 G C + E+ + LV EY+P S+ +L S+ L AQ G+ YLH Sbjct 149 LLGYCAEDDERGIQRLLVYEYMPNRSVEFHLSPRSLTVLTWDLRLRIAQDAARGLTYLHE 208 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + I RD + N+LLD D K+ DFGLA+ + V D + + APE + Sbjct 209 EMEFQIIFRDFKSSNILLDEDWKAKLSDFGLAR-LGPSEGLTHVSTDVVGTMGYAAPEYI 267 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELL-ERG 1131 + + SDVW +GV LYEL+T ++ P +L+ + ++ R +L+ + Sbjct 268 QTGRLTSKSDVWGYGVFLYELITGRRPVDRNRPKGEQKLLEWVRPYLSDTRKFKLILDPR 327 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 P K ++ + C + RP ++ ++ + E G Sbjct 328 LEGKYPIKSVQKLAVVANRCLVRNSKARPKMSEVLEMVNKIVEASSGN 375 Score = 216 bits (549), Expect = 4e-60, Method: Composition-based stats. Identities = 67/335 (20%), Positives = 120/335 (36%), Gaps = 62/335 (19%) Query 569 ASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 S R NL + S + K ++ +G+G V+ G +R Sbjct 62 VSTRASNLREFSITDLKSATKNFSRSVMIGEGGFGCVFRGTVRNL--------------- 106 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE---- 682 D ++ V +K L + + + V HT+L + G C E Sbjct 107 ----EDSSVKIEVAVKQLGKRGLQGHKEWVTEVNFLGIVEHTNLVKLLGYCAEDDERGIQ 162 Query 683 NIMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGR 738 ++V EY+ + ++ L R + ++ +AQ A L+YL + ++ + Sbjct 163 RLLVYEYMPNRSVEFHLSPRSLTVLTWDLRLRIAQDAARGLTYLHEEMEFQIIFRDFKSS 222 Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANSLS 792 NILL KLSD G+ S + V + + APE + G L+ Sbjct 223 NILLDE-------DWKAKLSDFGLARLGPSEGLTHVSTDVVGTMGYAAPEYIQTG--RLT 273 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL------------------P 834 + D WG+G L E+ ++R E++ + L P Sbjct 274 SKSDVWGYGVFLYELITGRRPVDRNRPKGEQKLLEWVRPYLSDTRKFKLILDPRLEGKYP 333 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 S +LA + ++CL RP +L + ++ Sbjct 334 IKSVQKLAVVANRCLVRNSKARPKMSEVLEMVNKI 368 >sp|O64780|Y1614_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61400 OS=Arabidopsis thaliana OX=3702 GN=At1g61400 PE=3 SV=4 Length=814 Score = 254 bits (650), Expect = 6e-70, Method: Composition-based stats. Identities = 77/307 (25%), Positives = 119/307 (39%), Gaps = 17/307 (6%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 + LG G FG V G +AVK L + Q + Sbjct 487 YFEMNTIQTATNNFSLSNKLGHGGFGSVYKGKLQ-----DGREIAVKRLSS-SSEQGKQE 540 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ 999 + EI ++ L H ++++ GCC + EK L+ E++ SL ++ R I + Sbjct 541 FMNEIVLISKLQHRNLVRVLGCCVEGTEK--LLIYEFMKNKSLDTFVFDSKKRLEIDWPK 598 Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 Q I G+ YLH IHRDL N+LLD KI DFGLA+ G EY Sbjct 599 RFDIIQGIARGLLYLHRDSRLRIIHRDLKVSNILLDEKMNPKISDFGLARMF-HGTEYQD 657 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIA 1115 + + +PE F SD++SFGV L E+++ S S + L+ A Sbjct 658 KTRRVVGTLGYMSPEYAWAGVFSEKSDIYSFGVLLLEIISGEKISRFSYGEEGKTLLAYA 717 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 R LL++ + C + + + RP L+ +L T + Sbjct 718 WECWCGARGVNLLDQALGDSCHPYEVGRCVQIGLLCVQYQPADRPNTLELLSMLTTTSDL 777 Query 1176 YQGQAPS 1182 + P+ Sbjct 778 PLPKQPT 784 Score = 234 bits (596), Expect = 7e-63, Method: Composition-based stats. Identities = 53/247 (21%), Positives = 96/247 (39%), Gaps = 45/247 (18%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L +++ + + + LG G +VY+G+L+ Sbjct 485 LEYFEMNTIQTATNNFSLSNKLGHGGFGSVYKGKLQDGR--------------------- 523 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + +K L S F L+S++ H +L V G CV G E +++ E++++ Sbjct 524 ----EIAVKRLSSSSEQGKQEFMNEIVLISKLQHRNLVRVLGCCVEGTEKLLIYEFMKNK 579 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748 LD ++ + + + W + + Q +A L YL ++H ++ NILL Sbjct 580 SLDTFVFDSKKRLEIDWPKRFDIIQGIARGLLYLHRDSRLRIIHRDLKVSNILLDEK--- 636 Query 749 EGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGA 802 K+SD G+ E + V + +++PE G S D + FG Sbjct 637 ----MNPKISDFGLARMFHGTEYQDKTRRVVGTLGYMSPEYAWAGV--FSEKSDIYSFGV 690 Query 803 TLLEICF 809 LLEI Sbjct 691 LLLEIIS 697 >sp|Q22146|FRK1_CAEEL Fer-related kinase 1 OS=Caenorhabditis elegans OX=6239 GN=frk-1 PE=1 SV=1 Length=390 Score = 243 bits (619), Expect = 6e-70, Method: Composition-based stats. Identities = 80/325 (25%), Positives = 143/325 (44%), Gaps = 23/325 (7%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 Q + ++ + A P + + + + LGEG FG V + Sbjct 88 HQESTISELINWHMTTKTPISAASGAKIRRPMERSPWLINHDSIVANKKLGEGAFGDVFI 147 Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 + G + VAVK ++A+ + R + +E ++R H+H++K G E Sbjct 148 AEL---DQGGKQEVAVKTMRAEATREARLRFMKEARLMRKYQHKHVVKLIGVAIH--EHP 202 Query 974 LQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033 L +VMEY P GSL +L ++ + L + L F + +G+AYL IHRD+AARN LL Sbjct 203 LMIVMEYCPNGSLLSHLKKNKVSLIEKLRFTTEAADGIAYLERSKCIHRDIAARNCLLSA 262 Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 +KI DFG++ + + + P+ W APE ++E + + +D+W+FGV ++E Sbjct 263 KNELKISDFGMS----DNKDEIKDETLEKVPIKWLAPETMQEKVYTHKTDIWTFGVLVWE 318 Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK-NCW 1152 + + TK +++ R+ PD V ++ CW Sbjct 319 IYSDGAEPYPGLTKIQTR-------------AKIVVNDYRMKMPDGTHPTVADVVTGTCW 365 Query 1153 ETEASFRPTFENLIPILKTVHEKYQ 1177 + R T +++ L+ +E + Sbjct 366 QKNPEKRSTMDSIHKKLREFYESKK 390 Score = 233 bits (593), Expect = 2e-66, Method: Composition-based stats. Identities = 81/429 (19%), Positives = 152/429 (35%), Gaps = 83/429 (19%) Query 448 RDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLIL--TVAQRSQAPDGMQSLRLRKF 505 + HG + + L+ E G +L+ + P +++L +V + R F Sbjct 21 AEYYHGMVPRQDAEGFLKRE-GDFLVRKTEQMPGKVVLAMSVRVTDELC--------RHF 71 Query 506 PIEQQD--GAFVLEGWGRSFPSVRELGA-ALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562 + F E + ++ EL + + +RR P Sbjct 72 MLNMDPTSNKFYFEHTHQE-STISELINWHMTTKTPISAASGAKIRRPMERSP------- 123 Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 ++ I LG+G +V+ L Sbjct 124 -------------------WLINHDSIVANKKLGEGAFGDVFIAEL-------------- 150 Query 623 DEDPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 D+G + V +K + + + L F + A LM + H H+ + GV + Sbjct 151 ---------DQGGKQEVAVKTMRAEATREARLRFMKEARLMRKYQHKHVVKLIGVAIHEH 201 Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 ++V EY +G L L++ + V + K+ + A ++YLE +H ++ RN L Sbjct 202 PLMIVMEYCPNGSLLSHLKKNK--VSLIEKLRFTTEAADGIAYLERSKCIHRDIAARNCL 259 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKW 798 L+ +K+SD G+ ++ I WLAPE + + D W Sbjct 260 LSAKNE-------LKISDFGMSDNKDEIKDETLEKVPIKWLAPETMQEKV--YTHKTDIW 310 Query 799 GFGATLLEICFDGEAPLQSRSPSE---KEHFYQRQHRLPEPSCPQLATLTS-QCLTYEPT 854 FG + EI DG P + + K + ++P+ + P +A + + C P Sbjct 311 TFGVLVWEIYSDGAEPYPGLTKIQTRAKIVVNDYRMKMPDGTHPTVADVVTGTCWQKNPE 370 Query 855 QRPSFRTIL 863 +R + +I Sbjct 371 KRSTMDSIH 379 >sp|Q9FZ36|M3K2_ARATH Mitogen-activated protein kinase kinase kinase 2 OS=Arabidopsis thaliana OX=3702 GN=ANP2 PE=2 SV=1 Length=651 Score = 251 bits (640), Expect = 6e-70, Method: Composition-based stats. Identities = 69/295 (23%), Positives = 130/295 (44%), Gaps = 28/295 (9%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-------K 933 S + +K + +G G FG V + N +GE++AVK + Sbjct 52 QSPPNNSTVQIKPPIRWRKGQLIGRGAFGTVYMGM----NLDSGELLAVKQVLITSNCAS 107 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993 + H ++E+ +L+ L H +I++Y G + +++L +++E+VP GS+ L + Sbjct 108 KEKTQAHIQELEEEVKLLKNLSHPNIVRYLGTVRE--DETLNILLEFVPGGSISSLLEKF 165 Query 994 S-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 + + + Q+ G+ YLH +HRD+ N+L+DN +K+ DFG +K V E Sbjct 166 GAFPESVVRTYTNQLLLGLEYLHNHAIMHRDIKGANILVDNQGCIKLADFGASKQVAELA 225 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 + +P +W APE + + +++D+WS G T+ E++T Sbjct 226 TISGAKSMKGTP-YWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAP------------ 272 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 +Q + + + P PD + + C + E + RPT L+ Sbjct 273 -WSQQYKEIAAIFHIGTTKSHPPIPDNISSDANDFLLKCLQQEPNLRPTASELLK 326 Score = 197 bits (500), Expect = 1e-51, Method: Composition-based stats. Identities = 60/308 (19%), Positives = 102/308 (33%), Gaps = 39/308 (13%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 S N S + + + +G+G VY G G + + + Sbjct 51 SQSPPNNSTVQIKPPIRW--RKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLITSNCASK 108 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 + + E L+ +SH ++ G ++ E+ Sbjct 109 EKTQAH----------------IQELEEEVKLLKNLSHPNIVRYLGTVREDETLNILLEF 152 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 V G + L + G P + QL L YL N ++H ++ G NIL+ G Sbjct 153 VPGGSISSLL-EKFGAFPESVVRTYTNQLLLGLEYLHNHAIMHRDIKGANILVDNQG--- 208 Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 IKL+D G + W+APE + +S S D W G T Sbjct 209 ----CIKLADFGASKQVAELATISGAKSMKGTPYWMAPEVILQTGHSFS--ADIWSVGCT 262 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQ----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859 ++E+ G+AP + F+ +P+ +CL EP RP+ Sbjct 263 VIEMV-TGKAPWSQQYKEIAAIFHIGTTKSHPPIPDNISSDANDFLLKCLQQEPNLRPTA 321 Query 860 RTILRDLT 867 +L+ Sbjct 322 SELLKHPF 329 >sp|A2VDU3|M3K7_BOVIN Mitogen-activated protein kinase kinase kinase 7 OS=Bos taurus OX=9913 GN=MAP3K7 PE=2 SV=1 Length=579 Score = 249 bits (635), Expect = 6e-70, Method: Composition-based stats. Identities = 73/284 (26%), Positives = 115/284 (40%), Gaps = 40/284 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + + VA+K ++++ R + E+ L + H +I+K Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQH 1018 G C + LVMEY GSL + L A + + Q +G+AYLH+ Sbjct 93 YGACL----NPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148 Query 1019 ---YIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL N+LL V KI DFG A + + W APE + Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTA------CDIQTHMTNNKGSAAWMAPEVFE 202 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + DV+S+G+ L+E++T + R+ + G R Sbjct 203 GSNYSEKCDVFSWGIILWEVITRRKPFD-------------EIGGPAFRIMWAVHNGTRP 249 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P P + LM CW + S RP+ E ++ I+ + + G Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293 Score = 211 bits (536), Expect = 9e-57, Method: Composition-based stats. Identities = 63/319 (20%), Positives = 116/319 (36%), Gaps = 47/319 (15%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 L+F +D KEI +G+G V + + R + Sbjct 24 QVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKD------------------------ 59 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K ++ AF +S+V+H ++ ++G C+ +V EY E G L Sbjct 60 --VAIKQIESESE--RKAFIVELRQLSRVNHPNIVKLYGACL--NPVCLVMEYAEGGSLY 113 Query 697 VWLRRER--GHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT 751 L + A M Q + ++YL + K L+H ++ N+LL G Sbjct 114 NVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGT---- 169 Query 752 SPFIKLSDPGVGLGA-LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +K+ D G W+APE G ++ S D + +G L E+ Sbjct 170 --VLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITR 225 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE---PSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + + P+ + + P + +L ++C + +P+QRPS I++ +T Sbjct 226 RKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMT 285 Query 868 RLQPHNLADVLTVNPDSPA 886 L + + Sbjct 286 HLMRYFPGADEPLQYPCQY 304 >sp|Q62073|M3K7_MOUSE Mitogen-activated protein kinase kinase kinase 7 OS=Mus musculus OX=10090 GN=Map3k7 PE=1 SV=1 Length=579 Score = 248 bits (634), Expect = 7e-70, Method: Composition-based stats. Identities = 73/284 (26%), Positives = 115/284 (40%), Gaps = 40/284 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + + VA+K ++++ R + E+ L + H +I+K Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQH 1018 G C + LVMEY GSL + L A + + Q +G+AYLH+ Sbjct 93 YGACL----NPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148 Query 1019 ---YIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL N+LL V KI DFG A + + W APE + Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTA------CDIQTHMTNNKGSAAWMAPEVFE 202 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + DV+S+G+ L+E++T + R+ + G R Sbjct 203 GSNYSEKCDVFSWGIILWEVITRRKPFD-------------EIGGPAFRIMWAVHNGTRP 249 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P P + LM CW + S RP+ E ++ I+ + + G Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293 Score = 210 bits (535), Expect = 1e-56, Method: Composition-based stats. Identities = 63/319 (20%), Positives = 116/319 (36%), Gaps = 47/319 (15%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 L+F +D KEI +G+G V + + R + Sbjct 24 QVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKD------------------------ 59 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K ++ AF +S+V+H ++ ++G C+ +V EY E G L Sbjct 60 --VAIKQIESESE--RKAFIVELRQLSRVNHPNIVKLYGACL--NPVCLVMEYAEGGSLY 113 Query 697 VWLRRER--GHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT 751 L + A M Q + ++YL + K L+H ++ N+LL G Sbjct 114 NVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGT---- 169 Query 752 SPFIKLSDPGVGLGA-LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +K+ D G W+APE G ++ S D + +G L E+ Sbjct 170 --VLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITR 225 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE---PSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + + P+ + + P + +L ++C + +P+QRPS I++ +T Sbjct 226 RKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMT 285 Query 868 RLQPHNLADVLTVNPDSPA 886 L + + Sbjct 286 HLMRYFPGADEPLQYPCQY 304 >sp|Q7YR43|DDR1_PANTR Epithelial discoidin domain-containing receptor 1 OS=Pan troglodytes OX=9598 GN=DDR1 PE=3 SV=1 Length=909 Score = 256 bits (653), Expect = 8e-70, Method: Composition-based stats. Identities = 98/315 (31%), Positives = 139/315 (44%), Gaps = 41/315 (13%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD------------PTNDGTGEMVAVKALKA 934 F + L+ LGEG FG+V L D G +VAVK L+ Sbjct 596 PPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRP 655 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993 D R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L H Sbjct 656 DATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSAHQ 713 Query 994 -------------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034 +I LL A QI GM YL +++HRDLA RN L+ + Sbjct 714 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN 773 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 +KI DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+ Sbjct 774 FTIKIADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEV 832 Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154 L C + ++I R L RP CP +Y LM CW Sbjct 833 LMLCRAQPFGQLTDEQVI------ENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSR 886 Query 1155 EASFRPTFENLIPIL 1169 E+ RP F L L Sbjct 887 ESEQRPPFSQLHRFL 901 Score = 229 bits (584), Expect = 6e-61, Method: Composition-based stats. Identities = 73/316 (23%), Positives = 123/316 (39%), Gaps = 52/316 (16%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + + LG+G V+ + + ++ +G L V +K+L Sbjct 602 PRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVR--------KGHPLLVAVKIL 653 Query 645 DPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 P A F + +MS++ ++ + GVCV+ M+T+Y+E+G L+ +L + Sbjct 654 RPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 713 Query 704 ------------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 + + VA Q+AS + YL N VH ++ RN L+ Sbjct 714 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV--- 770 Query 746 GLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWG 799 G + IK++D G+ + + V I W+A EC+ G +TA D W Sbjct 771 ----GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG--KFTTASDVWA 824 Query 800 FGATLLEI-CFDGEAPLQSRSPSEKE----HFYQRQHRL-----PEPSCPQLATLTSQCL 849 FG TL E+ P + + F++ Q R P L L +C Sbjct 825 FGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCW 884 Query 850 TYEPTQRPSFRTILRD 865 + E QRP F + R Sbjct 885 SRESEQRPPFSQLHRF 900 >sp|Q08345|DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 OS=Homo sapiens OX=9606 GN=DDR1 PE=1 SV=1 Length=913 Score = 256 bits (653), Expect = 8e-70, Method: Composition-based stats. Identities = 98/315 (31%), Positives = 139/315 (44%), Gaps = 41/315 (13%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD------------PTNDGTGEMVAVKALKA 934 F + L+ LGEG FG+V L D G +VAVK L+ Sbjct 600 PPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRP 659 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993 D R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L H Sbjct 660 DATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSAHQ 717 Query 994 -------------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034 +I LL A QI GM YL +++HRDLA RN L+ + Sbjct 718 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN 777 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 +KI DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+ Sbjct 778 FTIKIADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEV 836 Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154 L C + ++I R L RP CP +Y LM CW Sbjct 837 LMLCRAQPFGQLTDEQVI------ENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSR 890 Query 1155 EASFRPTFENLIPIL 1169 E+ RP F L L Sbjct 891 ESEQRPPFSQLHRFL 905 Score = 229 bits (584), Expect = 6e-61, Method: Composition-based stats. Identities = 73/316 (23%), Positives = 123/316 (39%), Gaps = 52/316 (16%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + + LG+G V+ + + ++ +G L V +K+L Sbjct 606 PRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVR--------KGHPLLVAVKIL 657 Query 645 DPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 P A F + +MS++ ++ + GVCV+ M+T+Y+E+G L+ +L + Sbjct 658 RPDATKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 717 Query 704 ------------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 + + VA Q+AS + YL N VH ++ RN L+ Sbjct 718 LEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV--- 774 Query 746 GLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWG 799 G + IK++D G+ + + V I W+A EC+ G +TA D W Sbjct 775 ----GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG--KFTTASDVWA 828 Query 800 FGATLLEI-CFDGEAPLQSRSPSEKE----HFYQRQHRL-----PEPSCPQLATLTSQCL 849 FG TL E+ P + + F++ Q R P L L +C Sbjct 829 FGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCW 888 Query 850 TYEPTQRPSFRTILRD 865 + E QRP F + R Sbjct 889 SRESEQRPPFSQLHRF 904 >sp|Q0D5R3|CRK6_ORYSJ Cysteine-rich receptor-like protein kinase 6 OS=Oryza sativa subsp. japonica OX=39947 GN=CRK6 PE=1 SV=1 Length=695 Score = 251 bits (642), Expect = 8e-70, Method: Composition-based stats. Identities = 85/332 (26%), Positives = 140/332 (42%), Gaps = 22/332 (7%) Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 C +RP +T L + D+ +++ + +G+G Sbjct 319 CWKRIKKRRPEEQTFLSYSV-----SSDDIQSIDSLILDLPTIRVATDDFADTKMIGQGG 373 Query 908 FGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 FG V G+ +AVK L Q K E+ ++ LYH+++++ G C Sbjct 374 FGMVYKGVL-----PDGQEIAVKRL-CQSSRQGIGELKSELILVAKLYHKNLVRLIGVCL 427 Query 968 DQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYI 1020 +Q EK LV EY+P GSL L + + I G+ YLH + Sbjct 428 EQQEK--ILVYEYMPNGSLDIVLFDTDKNRELDWGKRFKIINGIARGLQYLHEDSQLKIV 485 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDL A N+LLD D KI DFGLAK G + V + APE + Sbjct 486 HRDLKASNILLDFDYSPKISDFGLAKIFG-GDQSEDVTNRIAGTYGYMAPEYAMRGNYSI 544 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SDV+SFGV + E++T ++ S + + ++L+ + T + EL++ P + Sbjct 545 KSDVFSFGVLVLEIITGRRNTGSYDSGQDVDLLNLVWEHWTRGNVVELIDPSMGDHPPIE 604 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + H+ C + + + RPT ++ +L + Sbjct 605 QMLKCIHIGLLCVQKKPASRPTISSVNIMLSS 636 Score = 230 bits (587), Expect = 1e-62, Method: Composition-based stats. Identities = 67/379 (18%), Positives = 121/379 (32%), Gaps = 64/379 (17%) Query 517 EGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL 576 E +V + +L CF + + E + + ++++ Sbjct 289 EKTKNRIGTVLAIVMPAIAAILLMVVACFCCWKRIKKRRPEEQTFLSYSVSSDDIQSIDS 348 Query 577 SQLSFH--RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 L RV + +GQG VY+G L Sbjct 349 LILDLPTIRVATDDFADTKMIGQGGFGMVYKGVLPDGQ---------------------- 386 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 + +K L S L++++ H +L + GVC+ E I+V EY+ +G Sbjct 387 ---EIAVKRLCQSSRQGIGELKSELILVAKLYHKNLVRLIGVCLEQQEKILVYEYMPNGS 443 Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAE 749 LD+ L + + W + + +A L YL +VH ++ NILL Sbjct 444 LDIVLFDTDKNRELDWGKRFKIINGIARGLQYLHEDSQLKIVHRDLKASNILLD------ 497 Query 750 GTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 K+SD G+ ++APE G + S D + FG Sbjct 498 -FDYSPKISDFGLAKIFGGDQSEDVTNRIAGTYGYMAPEYAMRG--NYSIKSDVFSFGVL 554 Query 804 LLEICFDGEAPLQSRSPSEKEHF-----YQRQHRLPEPSCPQLAT------------LTS 846 +LEI S + + + + + E P + + Sbjct 555 VLEIITGRRNTGSYDSGQDVDLLNLVWEHWTRGNVVELIDPSMGDHPPIEQMLKCIHIGL 614 Query 847 QCLTYEPTQRPSFRTILRD 865 C+ +P RP+ ++ Sbjct 615 LCVQKKPASRPTISSVNIM 633 >sp|Q9FFW5|PERK8_ARATH Proline-rich receptor-like protein kinase PERK8 OS=Arabidopsis thaliana OX=3702 GN=PERK8 PE=1 SV=1 Length=681 Score = 251 bits (640), Expect = 9e-70, Method: Composition-based stats. Identities = 82/332 (25%), Positives = 126/332 (38%), Gaps = 19/332 (6%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 + P + + + +++ + D + LGEG FG V Sbjct 296 SSAPPKMRSHSGSDYMYASSDSGMVSNQRSWFSYDELSQVTSGFSEKNLLGEGGFGCVYK 355 Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 G VAVK LK G Q +K E++I+ ++H H++ G C + + Sbjct 356 GVL-----SDGREVAVKQLKIG-GSQGEREFKAEVEIISRVHHRHLVTLVGYCISEQHR- 408 Query 974 LQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAAR 1027 LV +YVP +L +L R + + A G+AYLH IHRD+ + Sbjct 409 -LLVYDYVPNNTLHYHLHAPGRPVMTWETRVRVAAGAARGIAYLHEDCHPRIIHRDIKSS 467 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 N+LLDN + DFGLAK E V + APE K +DV+S+ Sbjct 468 NILLDNSFEALVADFGLAKIAQELDLNTHVSTRVMGTFGYMAPEYATSGKLSEKADVYSY 527 Query 1088 GVTLYELLTHCDSSQ-SPPTKFLELIGIAQG----QMTVLRLTELLERGERLPRPDKCPC 1142 GV L EL+T S P L+ A+ + EL++ Sbjct 528 GVILLELITGRKPVDTSQPLGDESLVEWARPLLGQAIENEEFDELVDPRLGKNFIPGEMF 587 Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + C A+ RP ++ L T+ E Sbjct 588 RMVEAAAACVRHSAAKRPKMSQVVRALDTLEE 619 Score = 222 bits (566), Expect = 6e-60, Method: Composition-based stats. Identities = 62/308 (20%), Positives = 104/308 (34%), Gaps = 49/308 (16%) Query 540 AGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQ-LSFHRVD--QKEITQLSHLG 596 + F+ R P+ S M + S N S+ + ++ + LG Sbjct 287 SDVVLFNSRSSAPPKMRSHSGSDYMYASSDSGMVSNQRSWFSYDELSQVTSGFSEKNLLG 346 Query 597 QGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFY 656 +G VY+G L V +K L F Sbjct 347 EGGFGCVYKGVLSDGR-------------------------EVAVKQLKIGGSQGEREFK 381 Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVA 715 ++S+V H HL + G C+ ++V +YV + L L R + ++ VA Sbjct 382 AEVEIISRVHHRHLVTLVGYCISEQHRLLVYDYVPNNTLHYHLHAPGRPVMTWETRVRVA 441 Query 716 QQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-------LG 765 A ++YL ++H ++ NILL A ++D G+ L Sbjct 442 AGAARGIAYLHEDCHPRIIHRDIKSSNILLDNSFEAL-------VADFGLAKIAQELDLN 494 Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 + ++APE G LS D + +G LLE+ G P+ + P E Sbjct 495 THVSTRVMGTFGYMAPEYATSG--KLSEKADVYSYGVILLELI-TGRKPVDTSQPLGDES 551 Query 826 FYQRQHRL 833 + L Sbjct 552 LVEWARPL 559 >sp|Q9XEC6|CRK36_ARATH Cysteine-rich receptor-like protein kinase 36 OS=Arabidopsis thaliana OX=3702 GN=CRK36 PE=1 SV=1 Length=658 Score = 250 bits (639), Expect = 1e-69, Method: Composition-based stats. Identities = 81/365 (22%), Positives = 141/365 (39%), Gaps = 20/365 (5%) Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P RSP ++ + ++ R+ +P + + +R + Sbjct 255 RVPAPPRSPQTRQDYRVKKGRMFQPWSVVVVVFPTGINLAVFVAFVLAYRRMRRRIYTEI 314 Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931 + +D + LG+G FG V +G+ +AVK Sbjct 315 NKNSDSDGQATLRFDLGMILIATNEFSLENKLGQGGFGSVYKGIL-----PSGQEIAVKR 369 Query 932 LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL- 990 L A Q +K E+ +L L H +++K G C + E+ LV E+VP SL ++ Sbjct 370 L-AGGSGQGELEFKNEVLLLTRLQHRNLVKLLGFCNEGNEE--ILVYEHVPNSSLDHFIF 426 Query 991 ---PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGL 1044 R + + + G+ YLH IHRDL A N+LLD + K+ DFG+ Sbjct 427 DEDKRWLLTWDVRYRIIEGVARGLLYLHEDSQLRIIHRDLKASNILLDAEMNPKVADFGM 486 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 A+ + APE ++ +F SDV+SFGV L E+++ ++ Sbjct 487 ARLFNMDETRGETSR-VVGTYGYMAPEYVRHGQFSAKSDVYSFGVMLLEMISG---EKNK 542 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + L A + L +++ P ++ + C + A+ RPT + Sbjct 543 NFETEGLPAFAWKRWIEGELESIIDP-YLNENPRNEIIKLIQIGLLCVQENAAKRPTMNS 601 Query 1165 LIPIL 1169 +I L Sbjct 602 VITWL 606 Score = 238 bits (606), Expect = 2e-65, Method: Composition-based stats. Identities = 74/427 (17%), Positives = 132/427 (31%), Gaps = 72/427 (17%) Query 465 RPEDGLYLIHWSTS---HPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGR 521 G + S YR + P +S + R+ GR Sbjct 225 WDRVGGTVARPSCYFRWDDYRFAGAFDNLERVPAPPRSPQTRQD---------YRVKKGR 275 Query 522 SFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSF 581 F + + A F L + I + + + + L Sbjct 276 MFQPWSVVVVVFPTGINLAVFVAFVLAYR---RMRRRIYTEINKNSDSDGQATLRFDLGM 332 Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + E + + LGQG +VY+G L + + Sbjct 333 ILIATNEFSLENKLGQGGFGSVYKGILPSGQ-------------------------EIAV 367 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 K L L F L++++ H +L + G C G E I+V E+V + LD ++ Sbjct 368 KRLAGGSGQGELEFKNEVLLLTRLQHRNLVKLLGFCNEGNEEILVYEHVPNSSLDHFIFD 427 Query 702 ERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIK 756 E + W + + + +A L YL ++H ++ NILL K Sbjct 428 EDKRWLLTWDVRYRIIEGVARGLLYLHEDSQLRIIHRDLKASNILLD-------AEMNPK 480 Query 757 LSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 ++D G+ E R V ++APE + G S D + FG LLE+ Sbjct 481 VADFGMARLFNMDETRGETSRVVGTYGYMAPEYVRHG--QFSAKSDVYSFGVMLLEMISG 538 Query 811 GEAPLQ------------SRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPS 858 + + + P +L + C+ +RP+ Sbjct 539 EKNKNFETEGLPAFAWKRWIEGELESIIDPYLNENPRNEIIKLIQIGLLCVQENAAKRPT 598 Query 859 FRTILRD 865 +++ Sbjct 599 MNSVITW 605 >sp|O73791|TIE2_DANRE Angiopoietin-1 receptor OS=Danio rerio OX=7955 GN=tek PE=1 SV=1 Length=1116 Score = 258 bits (659), Expect = 1e-69, Method: Composition-based stats. Identities = 103/354 (29%), Positives = 152/354 (43%), Gaps = 40/354 (11%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 L QR + + S + ++ LGEG+F Sbjct 768 LKRNTLQRRIHSILREEPAVHFSSAPPPHRRSAVVSRSLVFPALQWSDIQFQDVLGEGNF 827 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY-HEHIIKYKGCCE 967 G+V DG AVK +K + E+++L L H++II G CE Sbjct 828 GQVLKA--RIRKDGLRMDAAVKRMKDYASQDDHRDFAGELEVLCRLGPHKNIIHLLGACE 885 Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRH-----------------SIGLAQLLLFAQQICEG 1010 +G L L +E+ P G+L D+L + ++ QLL F+ + G Sbjct 886 HRG--YLYLAIEFAPHGNLLDFLRKSRVLETDPAFAIAHRTASTLSSQQLLAFSADVARG 943 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 M+YL + +IHRDLAARNVL+ + + KI DFGL++ G E Y + G PV W A Sbjct 944 MSYLSQKQFIHRDLAARNVLVGENFVAKIADFGLSR----GQEVYVKKTMGRLPVRWMAI 999 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E L + SDVWS+GV L+E+++ L G MT L E L Sbjct 1000 ESLNYSVYTTNSDVWSYGVLLWEVVS--------------LGGTPYCGMTCAELYEKLPL 1045 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 G RL +P C EVY LM+ CW + RP+F ++ L + E+ + + Sbjct 1046 GFRLEKPLNCDDEVYELMQQCWREKPFERPSFSQILLSLGRMLEERKTYVNTTL 1099 Score = 228 bits (581), Expect = 7e-60, Method: Composition-based stats. Identities = 89/474 (19%), Positives = 163/474 (34%), Gaps = 62/474 (13%) Query 442 RLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLR 501 R + + P +L L + +T + +L TV ++ + Sbjct 666 RFQQVEQAQYRQQVELPVQTQQLHMRFQLLGLRPNTGYQLQLW-TVNNMGESAESPPVSL 724 Query 502 LRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQP-----G 556 + P ++ F G + + G +L A L+R L + Sbjct 725 MT-LPQQESSALFAAHGHLLLYAILGSAGMTC-CTVLLAFCIVLQLKRNTLQRRIHSILR 782 Query 557 ETSNLIIMRGARASPRTLNLS-QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615 E + R+ +S L F + +I LG+G V + R+R +G Sbjct 783 EEPAVHFSSAPPPHRRSAVVSRSLVFPALQWSDIQFQDVLGEGNFGQVLKARIRKDGL-- 840 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVS-HTHLAFV 673 + +K + + D F ++ ++ H ++ + Sbjct 841 --------------------RMDAAVKRMKDYASQDDHRDFAGELEVLCRLGPHKNIIHL 880 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRER---------------GHVPMAWKMVVAQQL 718 G C + E+ HG L +LR+ R + + + + Sbjct 881 LGACEHRGYLYLAIEFAPHGNLLDFLRKSRVLETDPAFAIAHRTASTLSSQQLLAFSADV 940 Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA-LSREERVERIP 777 A +SYL K +H ++ RN+L+ G + K++D G+ G + ++ + R+P Sbjct 941 ARGMSYLSQKQFIHRDLAARNVLV-------GENFVAKIADFGLSRGQEVYVKKTMGRLP 993 Query 778 --WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-- 833 W+A E L + +T D W +G L E+ G P + +E RL Sbjct 994 VRWMAIESL--NYSVYTTNSDVWSYGVLLWEVVSLGGTPYCGMTCAELYEKLPLGFRLEK 1051 Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 P ++ L QC +P +RPSF IL L R+ V T + Sbjct 1052 PLNCDDEVYELMQQCWREKPFERPSFSQILLSLGRMLEERKTYVNTTLYEKFTY 1105 >sp|P0C8E4|M3K7_RAT Mitogen-activated protein kinase kinase kinase 7 OS=Rattus norvegicus OX=10116 GN=Map3k7 PE=1 SV=1 Length=606 Score = 249 bits (635), Expect = 1e-69, Method: Composition-based stats. Identities = 73/284 (26%), Positives = 115/284 (40%), Gaps = 40/284 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + + VA+K ++++ R + E+ L + H +I+K Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQH 1018 G C + LVMEY GSL + L A + + Q +G+AYLH+ Sbjct 93 YGACL----NPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148 Query 1019 ---YIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL N+LL V KI DFG A + + W APE + Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTA------CDIQTHMTNNKGSAAWMAPEVFE 202 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + DV+S+G+ L+E++T + R+ + G R Sbjct 203 GSNYSEKCDVFSWGIILWEVITRRKPFD-------------EIGGPAFRIMWAVHNGTRP 249 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P P + LM CW + S RP+ E ++ I+ + + G Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293 Score = 211 bits (536), Expect = 1e-56, Method: Composition-based stats. Identities = 63/319 (20%), Positives = 116/319 (36%), Gaps = 47/319 (15%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 L+F +D KEI +G+G V + + R + Sbjct 24 QVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKD------------------------ 59 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K ++ AF +S+V+H ++ ++G C+ +V EY E G L Sbjct 60 --VAIKQIESESE--RKAFIVELRQLSRVNHPNIVKLYGACL--NPVCLVMEYAEGGSLY 113 Query 697 VWLRRER--GHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT 751 L + A M Q + ++YL + K L+H ++ N+LL G Sbjct 114 NVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGT---- 169 Query 752 SPFIKLSDPGVGLGA-LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +K+ D G W+APE G ++ S D + +G L E+ Sbjct 170 --VLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITR 225 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE---PSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + + P+ + + P + +L ++C + +P+QRPS I++ +T Sbjct 226 RKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMT 285 Query 868 RLQPHNLADVLTVNPDSPA 886 L + + Sbjct 286 HLMRYFPGADEPLQYPCQY 304 >sp|Q5RFL3|M3K7_PONAB Mitogen-activated protein kinase kinase kinase 7 OS=Pongo abelii OX=9601 GN=MAP3K7 PE=2 SV=1 Length=606 Score = 249 bits (635), Expect = 1e-69, Method: Composition-based stats. Identities = 73/284 (26%), Positives = 115/284 (40%), Gaps = 40/284 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + + VA+K ++++ R + E+ L + H +I+K Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQH 1018 G C + LVMEY GSL + L A + + Q +G+AYLH+ Sbjct 93 YGACL----NPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148 Query 1019 ---YIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL N+LL V KI DFG A + + W APE + Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTA------CDIQTHMTNNKGSAAWMAPEVFE 202 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + DV+S+G+ L+E++T + R+ + G R Sbjct 203 GSNYSEKCDVFSWGIILWEVITRRKPFD-------------EIGGPAFRIMWAVHNGTRP 249 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P P + LM CW + S RP+ E ++ I+ + + G Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293 Score = 211 bits (536), Expect = 1e-56, Method: Composition-based stats. Identities = 63/319 (20%), Positives = 116/319 (36%), Gaps = 47/319 (15%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 L+F +D KEI +G+G V + + R + Sbjct 24 QVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKD------------------------ 59 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K ++ AF +S+V+H ++ ++G C+ +V EY E G L Sbjct 60 --VAIKQIESESE--RKAFIVELRQLSRVNHPNIVKLYGACL--NPVCLVMEYAEGGSLY 113 Query 697 VWLRRER--GHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT 751 L + A M Q + ++YL + K L+H ++ N+LL G Sbjct 114 NVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGT---- 169 Query 752 SPFIKLSDPGVGLGA-LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +K+ D G W+APE G ++ S D + +G L E+ Sbjct 170 --VLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITR 225 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE---PSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + + P+ + + P + +L ++C + +P+QRPS I++ +T Sbjct 226 RKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMT 285 Query 868 RLQPHNLADVLTVNPDSPA 886 L + + Sbjct 286 HLMRYFPGADEPLQYPCQY 304 >sp|O43318|M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 OS=Homo sapiens OX=9606 GN=MAP3K7 PE=1 SV=1 Length=606 Score = 249 bits (635), Expect = 1e-69, Method: Composition-based stats. Identities = 73/284 (26%), Positives = 115/284 (40%), Gaps = 40/284 (14%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + + VA+K ++++ R + E+ L + H +I+K Sbjct 42 VGRGAFGVVCKAKWRAKD------VAIKQIESES---ERKAFIVELRQLSRVNHPNIVKL 92 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQH 1018 G C + LVMEY GSL + L A + + Q +G+AYLH+ Sbjct 93 YGACL----NPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQ 148 Query 1019 ---YIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL N+LL V KI DFG A + + W APE + Sbjct 149 PKALIHRDLKPPNLLLVAGGTVLKICDFGTA------CDIQTHMTNNKGSAAWMAPEVFE 202 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + DV+S+G+ L+E++T + R+ + G R Sbjct 203 GSNYSEKCDVFSWGIILWEVITRRKPFD-------------EIGGPAFRIMWAVHNGTRP 249 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P P + LM CW + S RP+ E ++ I+ + + G Sbjct 250 PLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPG 293 Score = 211 bits (536), Expect = 2e-56, Method: Composition-based stats. Identities = 63/319 (20%), Positives = 116/319 (36%), Gaps = 47/319 (15%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 L+F +D KEI +G+G V + + R + Sbjct 24 QVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKD------------------------ 59 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K ++ AF +S+V+H ++ ++G C+ +V EY E G L Sbjct 60 --VAIKQIESESE--RKAFIVELRQLSRVNHPNIVKLYGACL--NPVCLVMEYAEGGSLY 113 Query 697 VWLRRER--GHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT 751 L + A M Q + ++YL + K L+H ++ N+LL G Sbjct 114 NVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGT---- 169 Query 752 SPFIKLSDPGVGLGA-LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +K+ D G W+APE G ++ S D + +G L E+ Sbjct 170 --VLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEG--SNYSEKCDVFSWGIILWEVITR 225 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPE---PSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + + P+ + + P + +L ++C + +P+QRPS I++ +T Sbjct 226 RKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMT 285 Query 868 RLQPHNLADVLTVNPDSPA 886 L + + Sbjct 286 HLMRYFPGADEPLQYPCQY 304 >sp|C0LGE0|Y1765_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g07650 OS=Arabidopsis thaliana OX=3702 GN=At1g07650 PE=1 SV=1 Length=1014 Score = 257 bits (656), Expect = 1e-69, Method: Composition-based stats. Identities = 79/304 (26%), Positives = 132/304 (43%), Gaps = 23/304 (8%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R +GEG FG V G+++AVK L A +R + EI ++ L Sbjct 676 DNFDVTRKIGEGGFGSVYKGEL-----SEGKLIAVKQLSAKSRQGNRE-FVNEIGMISAL 729 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQLLLFAQQIC 1008 H +++K GCC + + L LV EY+ L L R + + I Sbjct 730 QHPNLVKLYGCCVEGNQ--LILVYEYLENNCLSRALFGKDESSRLKLDWSTRKKIFLGIA 787 Query 1009 EGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 +G+ +LH + +HRD+ A NVLLD D KI DFGLAK +G+ + R G + Sbjct 788 KGLTFLHEESRIKIVHRDIKASNVLLDKDLNAKISDFGLAKLNDDGNTHISTRIAG--TI 845 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQMTVLRL 1124 + APE +DV+SFGV E+++ ++ PT+ F+ L+ A L Sbjct 846 GYMAPEYAMRGYLTEKADVYSFGVVALEIVSGKSNTNFRPTEDFVYLLDWAYVLQERGSL 905 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK---TVHEKYQGQAP 1181 EL++ ++ + ++ C + RPT ++ +++ + E + Sbjct 906 LELVDPTLASDYSEEEAMLMLNVALMCTNASPTLRPTMSQVVSLIEGKTAMQELLSDPSF 965 Query 1182 SVFS 1185 S + Sbjct 966 STVN 969 Score = 225 bits (573), Expect = 4e-59, Method: Composition-based stats. Identities = 67/367 (18%), Positives = 126/367 (34%), Gaps = 69/367 (19%) Query 527 RELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNL-IIMRGARASPRTLNLSQLSFHRVD 585 +++ + + A F + + + +++ +RG T L Q+ + Sbjct 618 KDIILKVGVPVAAATLLLFIIVGVFWKKRRDKNDIDKELRGLDLQTGTFTLRQI---KAA 674 Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 +G+G +VY+G L + +K L Sbjct 675 TDNFDVTRKIGEGGFGSVYKGELSEGK-------------------------LIAVKQLS 709 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR----R 701 F ++S + H +L ++G CV G + I+V EY+E+ L L Sbjct 710 AKSRQGNREFVNEIGMISALQHPNLVKLYGCCVEGNQLILVYEYLENNCLSRALFGKDES 769 Query 702 ERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 R + + + + +A L++L + +VH ++ N+LL + K+S Sbjct 770 SRLKLDWSTRKKIFLGIAKGLTFLHEESRIKIVHRDIKASNVLLDK-------DLNAKIS 822 Query 759 DPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 D G+ + I ++APE G L+ D + FG LEI G++ Sbjct 823 DFGLAKLNDDGNTHISTRIAGTIGYMAPEYAMRGY--LTEKADVYSFGVVALEIVS-GKS 879 Query 814 PLQSRSPSEKEHFYQRQHRLPEPSC------PQLAT------------LTSQCLTYEPTQ 855 R + + + L E P LA+ + C PT Sbjct 880 NTNFRPTEDFVYLLDWAYVLQERGSLLELVDPTLASDYSEEEAMLMLNVALMCTNASPTL 939 Query 856 RPSFRTI 862 RP+ + Sbjct 940 RPTMSQV 946 >sp|Q9SR05|ANX1_ARATH Receptor-like protein kinase ANXUR1 OS=Arabidopsis thaliana OX=3702 GN=ANX1 PE=1 SV=1 Length=850 Score = 254 bits (649), Expect = 1e-69, Method: Composition-based stats. Identities = 74/296 (25%), Positives = 129/296 (44%), Gaps = 16/296 (5%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 + + +G G FGKV D T VAVK + Q Sbjct 502 CRRFSLPEIKHGTQNFDDSNVIGVGGFGKVYKGVIDGT-----TKVAVKKSNPN-SEQGL 555 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLA 998 + ++ EI++L L H+H++ G C++ GE + LV +Y+ G+LR++L + + Sbjct 556 NEFETEIELLSRLRHKHLVSLIGYCDEGGE--MCLVYDYMAFGTLREHLYNTKKPQLTWK 613 Query 999 QLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + L A G+ YLH IHRD+ N+L+D + + K+ DFGL+K P + + Sbjct 614 RRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILVDENWVAKVSDFGLSKTGPNMNGGH 673 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGI 1114 V + PE + + SDV+SFGV L+E+L + + S P + + L Sbjct 674 -VTTVVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLFEILCARPALNPSLPKEQVSLGDW 732 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 A L ++++ + +C + + C RPT +++ L+ Sbjct 733 AMNCKRKGNLEDIIDPNLKGKINAECLKKFADTAEKCLNDSGLERPTMGDVLWNLE 788 Score = 221 bits (562), Expect = 2e-58, Method: Composition-based stats. Identities = 64/348 (18%), Positives = 108/348 (31%), Gaps = 53/348 (15%) Query 579 LSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S + + + +G G VY+G + Sbjct 505 FSLPEIKHGTQNFDDSNVIGVGGFGKVYKGVIDGT------------------------- 539 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +V +K +P+ F L+S++ H HL + G C G E +V +Y+ G L Sbjct 540 TKVAVKKSNPNSEQGLNEFETEIELLSRLRHKHLVSLIGYCDEGGEMCLVYDYMAFGTLR 599 Query 697 VWLRR-ERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTS 752 L ++ + ++ +A A L YL ++H +V NIL+ + Sbjct 600 EHLYNTKKPQLTWKRRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILVDE-------N 652 Query 753 PFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 K+SD G+ G +L PE L+ D + FG L E Sbjct 653 WVAKVSDFGLSKTGPNMNGGHVTTVVKGSFGYLDPEYFR--RQQLTEKSDVYSFGVVLFE 710 Query 807 ICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLA-TLTSQCLTYEP-TQRPSF 859 I A P + S + +R+ L + P L + ++CL T Sbjct 711 ILCARPALNPSLPKEQVSLGDWAMNCKRKGNLEDIIDPNLKGKINAECLKKFADTAEKCL 770 Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 + + + A DLG G Sbjct 771 NDSGLERPTMGDVLWNLEFALQLQETADGTRHRTPNNGGSSEDLGRGG 818 >sp|Q98949|TYRO3_CHICK Tyrosine-protein kinase receptor TYRO3 OS=Gallus gallus OX=9031 GN=TYRO3 PE=1 SV=1 Length=873 Score = 254 bits (650), Expect = 1e-69, Method: Composition-based stats. Identities = 89/283 (31%), Positives = 131/283 (46%), Gaps = 28/283 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 LG+G FG V +DG+ + VAVK LKAD + +E ++ H H+ K Sbjct 511 LGKGEFGSVREALLK-LDDGSFQKVAVKMLKADIFTSTDIEEFLREAACMKEFDHPHVTK 569 Query 962 YKGCCEDQGEKS----LQLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEG 1010 G K +++ ++ G L +L ++ L LL F I G Sbjct 570 LIGVSLRSRPKGRLPIPMVILPFMKHGDLHAFLLMSRIGENPFNLPLQTLLKFMIDIASG 629 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 M YL ++++IHRDLAARN +LD + V + DFGL+K + G +YYR PV W A Sbjct 630 MEYLSSKNFIHRDLAARNCMLDENMNVSVADFGLSKKIYSG-DYYRQGCASKLPVKWLAL 688 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E L + + SDVW+FGVT++E++T + + L Sbjct 689 ESLADNLYTTHSDVWAFGVTMWEIVTRGQ--------------TPYAGIENAEIYNYLIS 734 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 G RL +P +C +VY LM CW E RP+F L L+ + Sbjct 735 GNRLKQPPECLEDVYDLMCRCWHPEPKLRPSFGVLRSQLEMIR 777 Score = 236 bits (601), Expect = 3e-63, Method: Composition-based stats. Identities = 68/314 (22%), Positives = 123/314 (39%), Gaps = 51/314 (16%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 +L + +++ T LG+G +V E L++ D G Sbjct 494 KLKDVLIQEQQFTLGRMLGKGEFGSVREALLKL---------------------DDGSFQ 532 Query 638 RVVLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN------IMVTEY 689 +V +K+L F A+ M + H H+ + GV +R +++ + Sbjct 533 KVAVKMLKADIFTSTDIEEFLREAACMKEFDHPHVTKLIGVSLRSRPKGRLPIPMVILPF 592 Query 690 VEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 ++HG L +L R ++P+ + +AS + YL +KN +H ++ RN +L Sbjct 593 MKHGDLHAFLLMSRIGENPFNLPLQTLLKFMIDIASGMEYLSSKNFIHRDLAARNCMLDE 652 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKW 798 + + ++D G+ S + + + WLA E L +T D W Sbjct 653 -------NMNVSVADFGLSKKIYSGDYYRQGCASKLPVKWLALESLADNL--YTTHSDVW 703 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 FG T+ EI G+ P +E ++ +RL P + L +C EP R Sbjct 704 AFGVTMWEIVTRGQTPYAGIENAEIYNYLISGNRLKQPPECLEDVYDLMCRCWHPEPKLR 763 Query 857 PSFRTILRDLTRLQ 870 PSF + L ++ Sbjct 764 PSFGVLRSQLEMIR 777 >sp|P08941|ROS1_CHICK Proto-oncogene tyrosine-protein kinase ROS OS=Gallus gallus OX=9031 GN=ROS1 PE=1 SV=3 Length=2311 Score = 260 bits (665), Expect = 2e-69, Method: Composition-based stats. Identities = 98/287 (34%), Positives = 136/287 (47%), Gaps = 33/287 (11%) Query 903 LGEGHFGKVSLYC-YDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG G FG+V D DG+GE VAVK LK Q +S + +E ++ H HI+ Sbjct 1967 LGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMSKFDHPHIL 2026 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--------LLLFAQQICEGMA 1012 K G C + L++E + G L YL Q LL IC+G Sbjct 2027 KLLGVCLLNEPQ--YLILELMEGGDLLSYLRGARKQKFQSPLLTLTDLLDICLDICKGCV 2084 Query 1013 YLHAQHYIHRDLAARNVLLDND------RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 YL +IHRDLAARN L+ R+VKIGDFGLA+ + + ++YYR R +G V Sbjct 2085 YLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLARDIYK-NDYYRKRGEGLINVR 2143 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE L + F SDVW+FGV ++E LT L ++ + + Sbjct 2144 WMAPESLIDGVFTNHSDVWAFGVLVWETLT--------------LGQQPYPGLSNIEVLH 2189 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + G RL P+ CP ++ LM CW + RPTF + L+ + Sbjct 2190 HVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEIR 2236 Score = 258 bits (658), Expect = 1e-68, Method: Composition-based stats. Identities = 73/315 (23%), Positives = 114/315 (36%), Gaps = 36/315 (11%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 S + ++ LG G VYEG L D E RV Sbjct 1952 SLPAFPRDKLNLHKLLGSGAFGEVYEG------------------TALDILADGSGESRV 1993 Query 640 VLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +K L D F + A LMS+ H H+ + GVC+ ++ E +E G L + Sbjct 1994 AVKTLKRGATDQEKSEFLKEAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSY 2053 Query 699 LRRERGH------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752 LR R + + + + + YLE +H ++ RN L++ S Sbjct 2054 LRGARKQKFQSPLLTLTDLLDICLDICKGCVYLEKMRFIHRDLAARNCLVSEKQYGSC-S 2112 Query 753 PFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 +K+ D G+ + +R + W+APE L G + D W FG + E Sbjct 2113 RVVKIGDFGLARDIYKNDYYRKRGEGLINVRWMAPESLIDGV--FTNHSDVWAFGVLVWE 2170 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 G+ P S E H + RL P + L ++C +P RP+F I Sbjct 2171 TLTLGQQPYPGLSNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQH 2230 Query 865 DLTRLQPHNLADVLT 879 L ++ L Sbjct 2231 KLQEIRHSPLCFSYF 2245 >sp|Q9LRP3|Y3174_ARATH Probable receptor-like protein kinase At3g17420 OS=Arabidopsis thaliana OX=3702 GN=At3g17420 PE=1 SV=1 Length=467 Score = 244 bits (623), Expect = 2e-69, Method: Composition-based stats. Identities = 61/303 (20%), Positives = 119/303 (39%), Gaps = 19/303 (6%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + K +G+G +G V VAVK L + G Sbjct 135 HIGWGHWFTLRDLQLATNHFSKESIIGDGGYGVVYHGTL-----TNKTPVAVKKLLNNPG 189 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR-----DYLPR 992 Q ++ E++ + + H+++++ G C + + LV EY+ G+L D + + Sbjct 190 -QADKDFRVEVEAIGHVRHKNLVRLLGYCVEGTHR--MLVYEYMNNGNLEQWLHGDMIHK 246 Query 993 HSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 + + + +AYLH +HRD+ + N+L+D++ K+ DFGLAK + Sbjct 247 GHLTWEARIKVLVGTAKALAYLHEAIEPKVVHRDIKSSNILMDDNFDAKLSDFGLAKLLG 306 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKF 1108 Y R + APE SDV+S+GV L E +T + P + Sbjct 307 ADSNYVSTR--VMGTFGYVAPEYANSGLLNEKSDVYSYGVVLLEAITGRYPVDYARPKEE 364 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 + ++ + + + E++++ + C + +A RP + + Sbjct 365 VHMVEWLKLMVQQKQFEEVVDKELEIKPTTSELKRALLTALRCVDPDADKRPKMSQVARM 424 Query 1169 LKT 1171 L++ Sbjct 425 LES 427 Score = 222 bits (566), Expect = 7e-62, Method: Composition-based stats. Identities = 69/342 (20%), Positives = 116/342 (34%), Gaps = 48/342 (14%) Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 + L ++ ++ S +G G VY G L Sbjct 140 HWFTLRDLQLATNHFSKESIIGDGGYGVVYHGTL-------------------------T 174 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 + V +K L + F + V H +L + G CV G ++V EY+ +G Sbjct 175 NKTPVAVKKLLNNPGQADKDFRVEVEAIGHVRHKNLVRLLGYCVEGTHRMLVYEYMNNGN 234 Query 695 LDVWLRR---ERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLA 748 L+ WL +GH+ ++ V A AL+YL +VH ++ NIL+ Sbjct 235 LEQWLHGDMIHKGHLTWEARIKVLVGTAKALAYLHEAIEPKVVHRDIKSSNILMD----- 289 Query 749 EGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 + KLSD G+ + V ++APE G L+ D + +G Sbjct 290 --DNFDAKLSDFGLAKLLGADSNYVSTRVMGTFGYVAPEYANSGL--LNEKSDVYSYGVV 345 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 LLE G P+ P E+ H + + + Q + + L +PT R +L Sbjct 346 LLEAI-TGRYPVDYARPKEEVHMVEWLKLMVQQK--QFEEVVDKELEIKPTTSELKRALL 402 Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 L + P ++ R + Sbjct 403 TALRCVDPDADKRPKMSQVARMLESDEYPVMPREERRRRRNQ 444 >sp|Q9ASQ5|CRCK3_ARATH Calmodulin-binding receptor-like cytoplasmic kinase 3 OS=Arabidopsis thaliana OX=3702 GN=CRCK3 PE=2 SV=1 Length=510 Score = 245 bits (626), Expect = 2e-69, Method: Composition-based stats. Identities = 77/283 (27%), Positives = 125/283 (44%), Gaps = 14/283 (5%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +GEG FG V D G++VA+K K + R+ +K E+D+L + H +++ Sbjct 229 HQIGEGGFGVVFKGVLD-----DGQVVAIKRAKKEHFENLRTEFKSEVDLLSKIGHRNLV 283 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA- 1016 K G + E+ ++ EYV G+LRD+L + Q L +C G+ YLH+ Sbjct 284 KLLGYVDKGDER--LIITEYVRNGTLRDHLDGARGTKLNFNQRLEIVIDVCHGLTYLHSY 341 Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 + IHRD+ + N+LL + K+ DFG A+ P + V + PE +K Sbjct 342 AERQIIHRDIKSSNILLTDSMRAKVADFGFARGGPTDSNQTHILTQVKGTVGYLDPEYMK 401 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 Y SDV+SFG+ L E+LT + + A + R+ EL++ R Sbjct 402 TYHLTAKSDVYSFGILLVEILTGRRPVEAKRLPDERITVRWAFDKYNEGRVFELVDPNAR 461 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 +K +++ L C RP E + L + Y Sbjct 462 ERVDEKILRKMFSLAFQCAAPTKKERPDMEAVGKQLWAIRSSY 504 Score = 216 bits (549), Expect = 3e-59, Method: Composition-based stats. Identities = 69/343 (20%), Positives = 124/343 (36%), Gaps = 66/343 (19%) Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 R +R P L +SQ++ +G+G V++G L Sbjct 204 RPSRLGPLNLTMSQINT---ATGNFADSHQIGEGGFGVVFKGVL---------------- 244 Query 625 DPLVPGRDRGQELRVVLKVLDPSH-HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 D GQ V +K H ++ F L+S++ H +L + G +G E Sbjct 245 -------DDGQ--VVAIKRAKKEHFENLRTEFKSEVDLLSKIGHRNLVKLLGYVDKGDER 295 Query 684 IMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRN 739 +++TEYV +G L L RG + ++ + + L+YL + + ++H ++ N Sbjct 296 LIITEYVRNGTLRDHLDGARGTKLNFNQRLEIVIDVCHGLTYLHSYAERQIIHRDIKSSN 355 Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-------ERIPWLAPECLPGGANSLS 792 ILL S K++D G G + + + +L PE + L+ Sbjct 356 ILLT-------DSMRAKVADFGFARGGPTDSNQTHILTQVKGTVGYLDPEYMKT--YHLT 406 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-----------------RQHRLPE 835 D + FG L+EI R P E+ + R+ E Sbjct 407 AKSDVYSFGILLVEILTGRRPVEAKRLPDERITVRWAFDKYNEGRVFELVDPNARERVDE 466 Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 ++ +L QC +RP + + L ++ L + Sbjct 467 KILRKMFSLAFQCAAPTKKERPDMEAVGKQLWAIRSSYLRRSM 509 >sp|O22042|M3K3_ARATH Mitogen-activated protein kinase kinase kinase 3 OS=Arabidopsis thaliana OX=3702 GN=ANP3 PE=1 SV=1 Length=651 Score = 249 bits (636), Expect = 2e-69, Method: Composition-based stats. Identities = 69/279 (25%), Positives = 128/279 (46%), Gaps = 28/279 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-------KADCGPQHRSGWKQEID 949 +K +G G FG+V + N +GE++A+K + + H ++E+ Sbjct 68 WRKGELIGCGAFGRVYMGM----NLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQ 123 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQIC 1008 +L+ L H +I++Y G + SL ++ME+VP GS+ L + S ++++ +Q+ Sbjct 124 LLKNLSHPNIVRYLGTVRESD--SLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLL 181 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 G+ YLH +HRD+ N+L+DN +++ DFG +K V E + +P +W Sbjct 182 LGLEYLHNNGIMHRDIKGANILVDNKGCIRLADFGASKKVVELATVNGAKSMKGTP-YWM 240 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 APE + + +++D+WS G T+ E+ T +F ++ I + + Sbjct 241 APEVILQTGHSFSADIWSVGCTVIEMATGKPPWSEQYQQFAAVLHIGRTKA--------- 291 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P P+ E + C E S R + L+ Sbjct 292 ----HPPIPEDLSPEAKDFLMKCLHKEPSLRLSATELLQ 326 Score = 199 bits (507), Expect = 2e-52, Method: Composition-based stats. Identities = 63/349 (18%), Positives = 111/349 (32%), Gaps = 37/349 (11%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 S++ R S L + +G G VY G G Sbjct 37 NSSIRSSRIGLFSKPPPGLPAPRKEEAPSIRWRKGELIGCGAFGRVYMGMNLDSGELLAI 96 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 + + + +G E L+ +SH ++ G Sbjct 97 KQVLIAPSSASKEKTQGH----------------IRELEEEVQLLKNLSHPNIVRYLGTV 140 Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737 ++ E+V G + L + G P ++ +QL L YL N ++H ++ G Sbjct 141 RESDSLNILMEFVPGGSISSLL-EKFGSFPEPVIIMYTKQLLLGLEYLHNNGIMHRDIKG 199 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANSL 791 NIL+ G I+L+D G + + W+APE + +S Sbjct 200 ANILVDNKG-------CIRLADFGASKKVVELATVNGAKSMKGTPYWMAPEVILQTGHSF 252 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR----LPEPSCPQLATLTSQ 847 S D W G T++E+ G+ P + + + + +PE P+ + Sbjct 253 S--ADIWSVGCTVIEMA-TGKPPWSEQYQQFAAVLHIGRTKAHPPIPEDLSPEAKDFLMK 309 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896 CL EP+ R S +L+ N + +P Sbjct 310 CLHKEPSLRLSATELLQHPFVTGKRQEPYPAYRNSLTECGNPITTQGMN 358 >sp|Q9C6K9|LRL11_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 1.1 OS=Arabidopsis thaliana OX=3702 GN=LRK10L-1.1 PE=2 SV=1 Length=629 Score = 249 bits (635), Expect = 2e-69, Method: Composition-based stats. Identities = 80/285 (28%), Positives = 131/285 (46%), Gaps = 19/285 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V G VAVK L + + + EI+IL L+H++++ Sbjct 297 LGDGGFGTVYYG-----KVRDGREVAVKRL-YEHNYRRLEQFMNEIEILTRLHHKNLVSL 350 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQLLLFAQQICEGMAYLHA 1016 G C + + L LV E++P G++ D+L + + + L A + +AYLHA Sbjct 351 YG-CTSRRSRELLLVYEFIPNGTVADHLYGENTPHQGFLTWSMRLSIAIETASALAYLHA 409 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ N+LLD + VK+ DFGL++ +P + G + PE + Y Sbjct 410 SDIIHRDVKTTNILLDRNFGVKVADFGLSRLLPSDVTHVSTAPQG--TPGYVDPEYHRCY 467 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 SDV+SFGV L EL++ + S + L +A ++ EL+++ Sbjct 468 HLTDKSDVYSFGVVLVELISSKPAVDISRCKSEINLSSLAINKIQNHATHELIDQNLGYA 527 Query 1136 RPD---KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 + K V L C + + + RPT E ++ LK + + Q Sbjct 528 TNEGVRKMTTMVAELAFQCLQQDNTMRPTMEQVVHELKGIQNEEQ 572 Score = 217 bits (553), Expect = 1e-58, Method: Composition-based stats. Identities = 65/353 (18%), Positives = 123/353 (35%), Gaps = 66/353 (19%) Query 574 LNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 + S+ + ++ LG G VY G++R Sbjct 274 FKIPIFSYKELQAATDNFSKDRLLGDGGFGTVYYGKVRDGR------------------- 314 Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV-CVRGPENIMVTEYV 690 V +K L ++ F +++++ H +L ++G R E ++V E++ Sbjct 315 ------EVAVKRLYEHNYRRLEQFMNEIEILTRLHHKNLVSLYGCTSRRSRELLLVYEFI 368 Query 691 EHGPLDVWLRRE----RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 +G + L E +G + + ++ +A + ASAL+YL +++H +V NILL R Sbjct 369 PNGTVADHLYGENTPHQGFLTWSMRLSIAIETASALAYLHASDIIHRDVKTTNILLDR-- 426 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFG 801 + +K++D G+ S V ++ PE L+ D + FG Sbjct 427 -----NFGVKVADFGLSRLLPSDVTHVSTAPQGTPGYVDPEY--HRCYHLTDKSDVYSFG 479 Query 802 ATLLEICFDGEAPLQSRSPSEK--------------------EHFYQRQHRLPEPSCPQL 841 L+E+ A SR SE ++ + + Sbjct 480 VVLVELISSKPAVDISRCKSEINLSSLAINKIQNHATHELIDQNLGYATNEGVRKMTTMV 539 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894 A L QCL + T RP+ ++ +L +Q + Sbjct 540 AELAFQCLQQDNTMRPTMEQVVHELKGIQNEEQKCPTYDYREETIIPHPSPPD 592 >sp|O76997|TRK1_LYMST Putative neurotrophin receptor LTRK 1 OS=Lymnaea stagnalis OX=6523 PE=2 SV=1 Length=794 Score = 253 bits (645), Expect = 2e-69, Method: Composition-based stats. Identities = 88/289 (30%), Positives = 136/289 (47%), Gaps = 37/289 (13%) Query 903 LGEGHFGKVSLY-CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG FG+V L C +VAVK LK C + +++E ++L T+ H +I+ Sbjct 510 IGEGAFGRVFLGTCAHLIQKNEFAIVAVKTLKGSCSDSLKRDFEREAEMLATIEHANIVT 569 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------------------IGLAQLLLF 1003 + G C + + ++ E++ G L YL H + QL+ Sbjct 570 FYGVCTESDQ--WMMIFEFMENGDLNKYLRMHGPDAAFLKDRDSMDSDEGQLTREQLMKI 627 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 QI M YL QH++HRDLA RN L+ D +VK+GDFG+++ V +YYRV Sbjct 628 VLQIASAMEYLALQHFVHRDLATRNCLVGCDLVVKLGDFGMSRDVY-TTDYYRVEGTAML 686 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 PV W PE + F SDVWSFGVTL+E+ T+ + + Sbjct 687 PVRWMPPESIIYRTFTTESDVWSFGVTLWEVFTYGKQ--------------PWFEYSNSE 732 Query 1124 LTELLERGERLPRPDK-CPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + E ++ L RP + C VY +M+ CW+ R T +++ +L+ Sbjct 733 VIEHIKNSRTLKRPPRTCTDGVYRVMQGCWKPNPQDRLTMKDIAELLRE 781 Score = 244 bits (622), Expect = 2e-66, Method: Composition-based stats. Identities = 64/327 (20%), Positives = 121/327 (37%), Gaps = 54/327 (17%) Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 ++ + +++ V + I + +G+G V+ G Sbjct 477 LVDNPNYNLTKKKHVATTCPKTVRLQTILLMRVIGEGAFGRVFLGTCAHL---------- 526 Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCVRG 680 + + V +K L S D + F A +++ + H ++ +GVC Sbjct 527 ---------IQKNEFAIVAVKTLKGSCSDSLKRDFEREAEMLATIEHANIVTFYGVCTES 577 Query 681 PENIMVTEYVEHGPLDVWLR----------------RERGHVPMAWKMVVAQQLASALSY 724 + +M+ E++E+G L+ +LR + G + M + Q+ASA+ Y Sbjct 578 DQWMMIFEFMENGDLNKYLRMHGPDAAFLKDRDSMDSDEGQLTREQLMKIVLQIASAMEY 637 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPW 778 L ++ VH ++ RN L+ G +KL D G+ + + + + W Sbjct 638 LALQHFVHRDLATRNCLV-------GCDLVVKLGDFGMSRDVYTTDYYRVEGTAMLPVRW 690 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ---HRLPE 835 + PE + + +T D W FG TL E+ G+ P S SE + R P Sbjct 691 MPPESII--YRTFTTESDVWSFGVTLWEVFTYGKQPWFEYSNSEVIEHIKNSRTLKRPPR 748 Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTI 862 + + C P R + + I Sbjct 749 TCTDGVYRVMQGCWKPNPQDRLTMKDI 775 >sp|O64781|Y1639_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61390 OS=Arabidopsis thaliana OX=3702 GN=At1g61390 PE=3 SV=1 Length=831 Score = 253 bits (647), Expect = 2e-69, Method: Composition-based stats. Identities = 81/345 (23%), Positives = 132/345 (38%), Gaps = 18/345 (5%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 Y Q + ++ + LG+G F Sbjct 472 WRYRTKQNEPNPMFIHSSQDAWAKDMEPQDVSGVNLFDMHTIRTATNNFSSSNKLGQGGF 531 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968 G V G+ +AVK L + G Q + EI ++ L H+++++ GCC Sbjct 532 GPVYKG-----KLVDGKEIAVKRLSSSSG-QGTDEFMNEIRLISKLQHKNLVRLLGCCIK 585 Query 969 QGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQ---HYIH 1021 EK L+ EY+ SL +L + I + Q + G+ YLH IH Sbjct 586 GEEK--LLIYEYLVNKSLDVFLFDSTLKFEIDWQKRFNIIQGVARGLLYLHRDSRLRVIH 643 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RDL N+LLD + KI DFGLA+ + +G +Y + + APE F Sbjct 644 RDLKVSNILLDEKMIPKISDFGLAR-MSQGTQYQDNTRRVVGTLGYMAPEYAWTGVFSEK 702 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 SD++SFGV L E++ S+ + L+ A + +LL++ Sbjct 703 SDIYSFGVLLLEIIIGEKISRF-SEEGKTLLAYAWESWCETKGVDLLDQALADSSHPAEV 761 Query 1142 CEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 + C + + + RP L+ +L T+ E + P F+V Sbjct 762 GRCVQIGLLCVQHQPADRPNTLELMSMLTTISELPSPKQP-TFTV 805 Score = 233 bits (595), Expect = 9e-63, Method: Composition-based stats. Identities = 57/247 (23%), Positives = 96/247 (39%), Gaps = 45/247 (18%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 +NL + R + + LGQG VY+G+L Sbjct 505 VNLFDMHTIRTATNNFSSSNKLGQGGFGPVYKGKLVDGK--------------------- 543 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + +K L S F L+S++ H +L + G C++G E +++ EY+ + Sbjct 544 ----EIAVKRLSSSSGQGTDEFMNEIRLISKLQHKNLVRLLGCCIKGEEKLLIYEYLVNK 599 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748 LDV+L + W + + Q +A L YL ++H ++ NILL + Sbjct 600 SLDVFLFDSTLKFEIDWQKRFNIIQGVARGLLYLHRDSRLRVIHRDLKVSNILLDEKMIP 659 Query 749 EGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGA 802 K+SD G+ + + + V + ++APE G S D + FG Sbjct 660 -------KISDFGLARMSQGTQYQDNTRRVVGTLGYMAPEYAWTGV--FSEKSDIYSFGV 710 Query 803 TLLEICF 809 LLEI Sbjct 711 LLLEIII 717 >sp|O65472|CRK12_ARATH Putative cysteine-rich receptor-like protein kinase 12 OS=Arabidopsis thaliana OX=3702 GN=CRK12 PE=3 SV=3 Length=659 Score = 249 bits (636), Expect = 2e-69, Method: Composition-based stats. Identities = 63/324 (19%), Positives = 115/324 (35%), Gaps = 65/324 (20%) Query 573 TLNLSQLSFH--RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 TL+ QL F V + + + LGQG VY+G L Sbjct 318 TLHFQQLDFKTIEVATENFAKTNKLGQGGFGEVYKGTLVNG------------------- 358 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 V +K L + A F L++++ H +L + G C+ E I+V E+V Sbjct 359 ------TEVAVKRLSKTSEQGAQEFKNEVVLVAKLQHRNLVKLLGYCLEPEEKILVYEFV 412 Query 691 EHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745 + LD +L ++G + + + + + YL + ++H ++ NILL Sbjct 413 PNKSLDYFLFDPTKQGQLDWTKRYNIIGGITRGILYLHQDSRLTIIHRDLKASNILLD-- 470 Query 746 GLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 K++D G+ + + ++ PE + G S D + Sbjct 471 -----ADMIPKIADFGMARISGIDQSVANTKRIAGTFGYMPPEYVIHG--QFSMKSDVYS 523 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------------QL 841 FG +LEI + ++ ++ E+ RL P + Sbjct 524 FGVLILEIICGKKNRSFYQADTKAENLVTYVWRLWTNGSPLELVDLTISENCQTEEVIRC 583 Query 842 ATLTSQCLTYEPTQRPSFRTILRD 865 + C+ +P RP+ TI+ Sbjct 584 IHIALLCVQEDPKDRPNLSTIMMM 607 Score = 247 bits (631), Expect = 1e-68, Method: Composition-based stats. Identities = 79/304 (26%), Positives = 118/304 (39%), Gaps = 26/304 (9%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH 940 + K LG+G FG+V G VAVK L Q Sbjct 320 HFQQLDFKTIEVATENFAKTNKLGQGGFGEVYKGTL-----VNGTEVAVKRLSK-TSEQG 373 Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIG 996 +K E+ ++ L H +++K G C + EK LV E+VP SL +L + + Sbjct 374 AQEFKNEVVLVAKLQHRNLVKLLGYCLEPEEK--ILVYEFVPNKSLDYFLFDPTKQGQLD 431 Query 997 LAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + I G+ YLH IHRDL A N+LLD D + KI DFG+A+ Sbjct 432 WTKRYNIIGGITRGILYLHQDSRLTIIHRDLKASNILLDADMIPKIADFGMARISGIDQS 491 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC--DSSQSPPTKFLEL 1111 + + PE + +F SDV+SFGV + E++ S TK L Sbjct 492 VANTKRIA-GTFGYMPPEYVIHGQFSMKSDVYSFGVLILEIICGKKNRSFYQADTKAENL 550 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCE----VYHLMKNCWETEASFRPTFENLIP 1167 + T EL++ L + C E H+ C + + RP ++ Sbjct 551 VTYVWRLWTNGSPLELVD----LTISENCQTEEVIRCIHIALLCVQEDPKDRPNLSTIMM 606 Query 1168 ILKT 1171 +L Sbjct 607 MLTN 610 >sp|Q9LSE1|CDG1_ARATH Serine/threonine-protein kinase CDG1 OS=Arabidopsis thaliana OX=3702 GN=CDG1 PE=1 SV=1 Length=432 Score = 243 bits (619), Expect = 2e-69, Method: Composition-based stats. Identities = 79/288 (27%), Positives = 131/288 (45%), Gaps = 27/288 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V TG+ +AVK L G Q + E+ +L L+H +++ Sbjct 80 IGRGGFGTVYKGRL-----STGQNIAVKMLDQ-SGIQGDKEFLVEVLMLSLLHHRNLVHL 133 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 G C + ++ +V EY+PLGS+ D+L + ++ + A +G+A+LH + Sbjct 134 FGYCAEGDQR--LVVYEYMPLGSVEDHLYDLSEGQEALDWKTRMKIALGAAKGLAFLHNE 191 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 I+RDL N+LLD+D K+ DFGLAK P + V + APE Sbjct 192 AQPPVIYRDLKTSNILLDHDYKPKLSDFGLAKFGPSDDMSH-VSTRVMGTHGYCAPEYAN 250 Query 1075 EYKFYYASDVWSFGVTLYELLTHC----DSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 K SD++SFGV L EL++ SS+ + L+ A+ R+ ++++ Sbjct 251 TGKLTLKSDIYSFGVVLLELISGRKALMPSSECVGNQSRYLVHWARPLFLNGRIRQIVDP 310 Query 1131 GERLPRPDKCPCEV----YHLMKNCWETEASFRPTFENLIPILKTVHE 1174 RL R + + C EA+ RP+ ++ LK + + Sbjct 311 --RLARKGGFSNILLYRGIEVAFLCLAEEANARPSISQVVECLKYIID 356 Score = 222 bits (566), Expect = 3e-62, Method: Composition-based stats. Identities = 69/351 (20%), Positives = 125/351 (36%), Gaps = 71/351 (20%) Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615 +S ++ +R + + +L+ + S +G+G VY+GRL + Sbjct 44 SSSSQTVVQDSSRYRCQIFSYRELA---IATNSFRNESLIGRGGFGTVYKGRLSTGQN-- 98 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675 + +K+LD S F ++S + H +L + G Sbjct 99 -----------------------IAVKMLDQSGIQGDKEFLVEVLMLSLLHHRNLVHLFG 135 Query 676 VCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYLENK---N 729 C G + ++V EY+ G ++ L G + W +M +A A L++L N+ Sbjct 136 YCAEGDQRLVVYEYMPLGSVEDHLYDLSEGQEALDWKTRMKIALGAAKGLAFLHNEAQPP 195 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPEC 783 +++ ++ NILL KLSD G+ S + + + APE Sbjct 196 VIYRDLKTSNILLDHDYKP-------KLSDFGLAKFGPSDDMSHVSTRVMGTHGYCAPEY 248 Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGE--APLQSRSPSEKEHFYQR------QHRLPE 835 G L+ D + FG LLE+ + P ++ + R+ + Sbjct 249 ANTG--KLTLKSDIYSFGVVLLELISGRKALMPSSECVGNQSRYLVHWARPLFLNGRIRQ 306 Query 836 PSCPQLA--------------TLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 P+LA + CL E RPS ++ L + H Sbjct 307 IVDPRLARKGGFSNILLYRGIEVAFLCLAEEANARPSISQVVECLKYIIDH 357 >sp|P08069|IGF1R_HUMAN Insulin-like growth factor 1 receptor OS=Homo sapiens OX=9606 GN=IGF1R PE=1 SV=1 Length=1367 Score = 259 bits (661), Expect = 2e-69, Method: Composition-based stats. Identities = 92/312 (29%), Positives = 144/312 (46%), Gaps = 29/312 (9%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALK 933 D D + + R+LG+G FG V E VA+K + Sbjct 977 NPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVN 1036 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR- 992 + R + E +++ H+++ G QG+ +L ++ME + G L+ YL Sbjct 1037 EAASMRERIEFLNEASVMKEFNCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSL 1094 Query 993 ----------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 L++++ A +I +GMAYL+A ++HRDLAARN ++ D VKIGDF Sbjct 1095 RPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDF 1154 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 G+ + + E +YYR G PV W +PE LK+ F SDVWSFGV L+E+ T Sbjct 1155 GMTRDIYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIAT------ 1207 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 L ++ ++ + G L +PD CP ++ LM+ CW+ RP+F Sbjct 1208 --------LAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSF 1259 Query 1163 ENLIPILKTVHE 1174 +I +K E Sbjct 1260 LEIISSIKEEME 1271 Score = 252 bits (644), Expect = 3e-67, Method: Composition-based stats. Identities = 99/488 (20%), Positives = 172/488 (35%), Gaps = 87/488 (18%) Query 425 RLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLI 484 +L +S+++ P D I GP+ RPE+ ++L +P LI Sbjct 812 KLGCSASNFVFARTMPA----EGADDIPGPVTWE-----PRPENSIFLKWPEPENPNGLI 862 Query 485 LTVAQR-SQAPDGMQSL----RLRKFPIEQQD-----------GAFVLEGWGR------- 521 L + + + RK+ + + A L G G Sbjct 863 LMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFF 922 Query 522 ------SFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLN 575 + + L AL +L + + + + A +P + Sbjct 923 YVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFS 982 Query 576 LSQL---SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 + + V +++IT LGQG+ VYEG + +P Sbjct 983 AADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEP---------------- 1026 Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 E RV +K ++ + + F AS+M + + H+ + GV +G +++ E + Sbjct 1027 ---ETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMT 1083 Query 692 HGPLDVWLRRERGHV---------PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 G L +LR R + ++ + +A ++A ++YL VH ++ RN ++ Sbjct 1084 RGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV 1143 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMD 796 A +K+ D G+ + + + W++PE L G +T D Sbjct 1144 AE-------DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTYSD 1194 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854 W FG L EI E P Q S + F L P+ L L C Y P Sbjct 1195 VWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPK 1254 Query 855 QRPSFRTI 862 RPSF I Sbjct 1255 MRPSFLEI 1262 >sp|Q54VC0|Y9865_DICDI Probable serine/threonine-protein kinase DDB_G0280461 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0280461 PE=3 SV=1 Length=418 Score = 242 bits (617), Expect = 2e-69, Method: Composition-based stats. Identities = 76/306 (25%), Positives = 129/306 (42%), Gaps = 34/306 (11%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHR 941 D + + + +G F KV Y G V VK +K D + Sbjct 1 MKIKDFNIECDNLKIEENEFSKGSFAKVYKGSY------YGNPVCVKVIKKDTLIDKESW 54 Query 942 SGWKQEIDILRTL---YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI--G 996 K+EI IL+ L H++II++ G + + L LV E + G L + L H Sbjct 55 VFLKREIGILKNLLNQGHKNIIRFIGI--GEKDSLLFLVTELINGGDLGNILLDHKFHIP 112 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 + + A+ I EGM YLH++ +HRDL + N+LL + +KI DFG AK + + Sbjct 113 WSLRVKIAKDIAEGMEYLHSKQIMHRDLKSNNLLLGRNWTIKICDFGFAKEITIQNP--- 169 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 + + +PE + ++ Y++D++SFG+ L EL+T + P ++ Sbjct 170 LSMTICGTDEFMSPEVILGIQYSYSADIYSFGMVLLELITRSKLDERLPQNNFDIDY--- 226 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 + P +CP E L C + + RP+F +++ L + K Sbjct 227 -------------EELQNKIPSECPREFLELSMKCCNYDPNDRPSFTDIVQTLDQLAIKL 273 Query 1177 QGQAPS 1182 + P Sbjct 274 VKETPD 279 Score = 199 bits (506), Expect = 2e-54, Method: Composition-based stats. Identities = 59/331 (18%), Positives = 122/331 (37%), Gaps = 51/331 (15%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 ++++ E + +G+ VY+G V +K Sbjct 14 KIEENEFS------KGSFAKVYKGSYYGN--------------------------PVCVK 41 Query 643 VLDPS---HHDIALAFYETASLMSQV---SHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V+ + + ++ + H ++ G+ + +VTE + G L Sbjct 42 VIKKDTLIDKESWVFLKREIGILKNLLNQGHKNIIRFIGIGEKDSLLFLVTELINGGDLG 101 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 L + H+P + ++ +A+ +A + YL +K ++H ++ N+LL R + IK Sbjct 102 NILLDHKFHIPWSLRVKIAKDIAEGMEYLHSKQIMHRDLKSNNLLLGR-------NWTIK 154 Query 757 LSDPGVGLGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 + D G + I +++PE + G S S D + FG LLE+ + Sbjct 155 ICDFGFAKEITIQNPLSMTICGTDEFMSPEVILGIQYSYS--ADIYSFGMVLLELITRSK 212 Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 + + + + Q+++P + L+ +C Y+P RPSF I++ L +L Sbjct 213 LDERLPQNNFDIDYEELQNKIPSECPREFLELSMKCCNYDPNDRPSFTDIVQTLDQLAIK 272 Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 + + S + H Sbjct 273 LVKETPDGPYPSTPIVVSNPHFDDQSINDWC 303 >sp|P00535|ERBB_AVIER Tyrosine-protein kinase transforming protein erbB OS=Avian erythroblastosis virus (strain ES4) OX=79685 GN=V-ERBB PE=3 SV=1 Length=604 Score = 248 bits (632), Expect = 2e-69, Method: Composition-based stats. Identities = 90/272 (33%), Positives = 134/272 (49%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG + + P + VA+K L+ P+ E ++ ++ + H+ + Sbjct 138 LGSGAFGTIYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRL 197 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C +QL+ + +P G L DY+ H IG LL + QI +GM YL + + Sbjct 198 LGICLTST---VQLITQLMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLV 254 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ + VKI DFGLAK + + Y E G P+ W A E + + + Sbjct 255 HRDLAARNVLVKTPQHVKITDFGLAKLLGADEKEYHA-EGGKVPIKWMALESILHRIYTH 313 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + ++ +LE+GERLP+P C Sbjct 314 QSDVWSYGVTVWELMTFGSK--------------PYDGIPASEISSVLEKGERLPQPPIC 359 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW +A RP F LI + Sbjct 360 TIDVYMIMVKCWMIDADSRPKFRELIAEFSKM 391 Score = 223 bits (569), Expect = 6e-61, Method: Composition-based stats. Identities = 67/345 (19%), Positives = 136/345 (39%), Gaps = 39/345 (11%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P +Q + + E ++ LG G +Y+G EG Sbjct 113 TPSGEAPNQAHLRILKETEFKKVKVLGSGAFGTIYKGLWIPEGEKV-------------- 158 Query 630 GRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ V +K L + + A +M+ V + H+ + G+C+ ++T+ Sbjct 159 ------KIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQ-LITQ 211 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + +G L ++R + ++ + + Q+A ++YLE + LVH ++ RN+L+ Sbjct 212 LMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLVHRDLAARNVLV------ 265 Query 749 EGTSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGA 802 T +K++D G+ LGA +E E I W+A E + + D W +G Sbjct 266 -KTPQHVKITDFGLAKLLGADEKEYHAEGGKVPIKWMALESILHRI--YTHQSDVWSYGV 322 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860 T+ E+ G P SE ++ RLP+P + + +C + RP FR Sbjct 323 TVWELMTFGSKPYDGIPASEISSVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFR 382 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 ++ + +++ ++ + K Y + + Sbjct 383 ELIAEFSKMARDPPRYLVIQGDERMHLPSPTDSKFYRTLMEEEDM 427 >sp|Q8LEB6|Y5185_ARATH Probable receptor-like protein kinase At5g18500 OS=Arabidopsis thaliana OX=3702 GN=At5g18500 PE=2 SV=1 Length=484 Score = 244 bits (623), Expect = 3e-69, Method: Composition-based stats. Identities = 65/307 (21%), Positives = 115/307 (37%), Gaps = 19/307 (6%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933 + +G+G +G V N G VAVK L Sbjct 143 PEFSHLGWGHWFTLRDLQMATNQFSRDNIIGDGGYGVVYRG-----NLVNGTPVAVKKLL 197 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991 + G Q ++ E++ + + H+++++ G C + ++ LV EYV G+L +L Sbjct 198 NNLG-QADKDFRVEVEAIGHVRHKNLVRLLGYCMEGTQR--MLVYEYVNNGNLEQWLRGD 254 Query 992 ---RHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 + + + +AYLH +HRD+ + N+L+D+ KI DFGLA Sbjct 255 NQNHEYLTWEARVKILIGTAKALAYLHEAIEPKVVHRDIKSSNILIDDKFNSKISDFGLA 314 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSP 1104 K + + R + APE SDV+SFGV L E +T + Sbjct 315 KLLGADKSFITTR--VMGTFGYVAPEYANSGLLNEKSDVYSFGVVLLEAITGRYPVDYAR 372 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 P + L+ + + R E+++ C + + RP Sbjct 373 PPPEVHLVEWLKMMVQQRRSEEVVDPNLETKPSTSALKRTLLTALRCVDPMSEKRPRMSQ 432 Query 1165 LIPILKT 1171 + +L++ Sbjct 433 VARMLES 439 Score = 217 bits (553), Expect = 6e-60, Method: Composition-based stats. Identities = 64/344 (19%), Positives = 117/344 (34%), Gaps = 48/344 (14%) Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 + L ++ + ++ + +G G VY G L Sbjct 152 HWFTLRDLQMATNQFSRDNIIGDGGYGVVYRGNLVNG----------------------- 188 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 V +K L + F + V H +L + G C+ G + ++V EYV +G Sbjct 189 --TPVAVKKLLNNLGQADKDFRVEVEAIGHVRHKNLVRLLGYCMEGTQRMLVYEYVNNGN 246 Query 695 LDVWLRRERGH---VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLA 748 L+ WLR + + + ++ + A AL+YL +VH ++ NIL+ + Sbjct 247 LEQWLRGDNQNHEYLTWEARVKILIGTAKALAYLHEAIEPKVVHRDIKSSNILIDDKFNS 306 Query 749 EGTSPFIKLSDPGVGLGALSREE-----RVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 K+SD G+ + + + ++APE G L+ D + FG Sbjct 307 -------KISDFGLAKLLGADKSFITTRVMGTFGYVAPEYANSGL--LNEKSDVYSFGVV 357 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 LLE +R P E + + + ++ L +P+ RT+L Sbjct 358 LLEAITGRYPVDYARPPPEVHLVEWLKMMVQQRRSEEVVDP---NLETKPSTSALKRTLL 414 Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 L + P + R ++ R G Sbjct 415 TALRCVDPMSEKRPRMSQVARMLESEEYPIAREDRRRRRSQNGT 458 >sp|O64784|Y1136_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61360 OS=Arabidopsis thaliana OX=3702 GN=At1g61360 PE=2 SV=1 Length=821 Score = 253 bits (645), Expect = 3e-69, Method: Composition-based stats. Identities = 85/354 (24%), Positives = 133/354 (38%), Gaps = 19/354 (5%) Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897 C L + C Y Q S ++ +L + Sbjct 439 CLILVLVACGCWRYRVKQNGSSLVSKDNVEGAWKSDLQSQDVSGLNFFEIHDLQTATNNF 498 Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 + LG+G FG V G+ +AVK L Q + EI ++ L H Sbjct 499 SVLNKLGQGGFGTVYKGKLQ-----DGKEIAVKRL-TSSSVQGTEEFMNEIKLISKLQHR 552 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSL----RDYLPRHSIGLAQLLLFAQQICEGMAY 1013 ++++ GCC D EK LV EY+ SL D + I A Q I G+ Y Sbjct 553 NLLRLLGCCIDGEEK--LLVYEYMVNKSLDIFIFDLKKKLEIDWATRFNIIQGIARGLLY 610 Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 LH +HRDL N+LLD KI DFGLA+ G+++ + + +P Sbjct 611 LHRDSFLRVVHRDLKVSNILLDEKMNPKISDFGLARLF-HGNQHQDSTGSVVGTLGYMSP 669 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E F SD++SFGV + E++T + SS S L+ A + LL+ Sbjct 670 EYAWTGTFSEKSDIYSFGVLMLEIITGKEISSFSYGKDNKNLLSYAWDSWSENGGVNLLD 729 Query 1130 RGERLPRPDKCPC--EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 + H+ C + +A RP + ++ +L + + + P Sbjct 730 QDLDDSDSVNSVEAGRCVHIGLLCVQHQAIDRPNIKQVMSMLTSTTDLPKPTQP 783 Score = 237 bits (605), Expect = 4e-64, Method: Composition-based stats. Identities = 57/250 (23%), Positives = 98/250 (39%), Gaps = 45/250 (18%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 LN ++ + + L+ LGQG VY+G+L+ Sbjct 483 LNFFEIHDLQTATNNFSVLNKLGQGGFGTVYKGKLQDGK--------------------- 521 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + +K L S F L+S++ H +L + G C+ G E ++V EY+ + Sbjct 522 ----EIAVKRLTSSSVQGTEEFMNEIKLISKLQHRNLLRLLGCCIDGEEKLLVYEYMVNK 577 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748 LD+++ + + + W + + Q +A L YL +VH ++ NILL Sbjct 578 SLDIFIFDLKKKLEIDWATRFNIIQGIARGLLYLHRDSFLRVVHRDLKVSNILLDEK--- 634 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 K+SD G+ S V + +++PE G + S D + FG Sbjct 635 ----MNPKISDFGLARLFHGNQHQDSTGSVVGTLGYMSPEYAWTG--TFSEKSDIYSFGV 688 Query 803 TLLEICFDGE 812 +LEI E Sbjct 689 LMLEIITGKE 698 >sp|O81832|Y4729_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At4g27290 OS=Arabidopsis thaliana OX=3702 GN=At4g27290 PE=3 SV=4 Length=783 Score = 252 bits (643), Expect = 3e-69, Method: Composition-based stats. Identities = 80/275 (29%), Positives = 118/275 (43%), Gaps = 18/275 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG+G FG V G+ VAVK L Q +K EI ++ L H +++ Sbjct 469 NKLGQGGFGPVYKGTL-----ACGQEVAVKRLSR-TSRQGVEEFKNEIKLIAKLQHRNLV 522 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016 K G C D+ E+ L+ EY P SL ++ R + + + + I GM YLH Sbjct 523 KILGYCVDEEER--MLIYEYQPNKSLDSFIFDKERRRELDWPKRVEIIKGIARGMLYLHE 580 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRDL A NVLLD+D KI DFGLA+ + G E + +PE Sbjct 581 DSRLRIIHRDLKASNVLLDSDMNAKISDFGLARTLG-GDETEANTTRVVGTYGYMSPEYQ 639 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + F SDV+SFGV + E+++ L L+G A Q + E+++ Sbjct 640 IDGYFSLKSDVFSFGVLVLEIVSGRRNRGFRNEEHKLNLLGHAWRQFLEDKAYEIIDEAV 699 Query 1133 RLPRPD-KCPCEVYHLMKNCWETEASFRPTFENLI 1166 D V H+ C + + RP ++ Sbjct 700 NESCTDISEVLRVIHIGLLCVQQDPKDRPNMSVVV 734 Score = 236 bits (601), Expect = 8e-64, Method: Composition-based stats. Identities = 62/377 (16%), Positives = 115/377 (31%), Gaps = 65/377 (17%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 S+ + R L L + + LGQG VY+G L Sbjct 434 ESSRVSSRKQEEEDLELPFLDLDTVSEATSGFSAGNKLGQGGFGPVYKGTLACGQ----- 488 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 V +K L + F L++++ H +L + G C Sbjct 489 --------------------EVAVKRLSRTSRQGVEEFKNEIKLIAKLQHRNLVKILGYC 528 Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVH 732 V E +++ EY + LD ++ + + W ++ + + +A + YL ++H Sbjct 529 VDEEERMLIYEYQPNKSLDSFIFDKERRRELDWPKRVEIIKGIARGMLYLHEDSRLRIIH 588 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPG 786 ++ N+LL + K+SD G+ E V +++PE Sbjct 589 RDLKASNVLLD-------SDMNAKISDFGLARTLGGDETEANTTRVVGTYGYMSPEYQID 641 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP------------ 834 G S D + FG +LEI G R+ K + R Sbjct 642 GY--FSLKSDVFSFGVLVLEIVS-GRRNRGFRNEEHKLNLLGHAWRQFLEDKAYEIIDEA 698 Query 835 -EPSCPQLATLTS------QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 SC ++ + C+ +P RP+ ++ L+ + Sbjct 699 VNESCTDISEVLRVIHIGLLCVQQDPKDRPNMSVVVLMLSSEMLLLDPRQPGFFNERNLL 758 Query 888 DPTVFHKRYLKKIRDLG 904 + Sbjct 759 FSDTVSINLEIPSNNFQ 775 >sp|Q3E8W4|ANX2_ARATH Receptor-like protein kinase ANXUR2 OS=Arabidopsis thaliana OX=3702 GN=ANX2 PE=1 SV=1 Length=858 Score = 253 bits (647), Expect = 3e-69, Method: Composition-based stats. Identities = 78/310 (25%), Positives = 133/310 (43%), Gaps = 23/310 (7%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 + + +G G FGKV D G VA+K + Q Sbjct 506 CRRFSLSEIKHGTHNFDESNVIGVGGFGKVYKGVIDG-----GTKVAIKKSNPN-SEQGL 559 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLA 998 + ++ EI++L L H+H++ G C++ GE + L+ +Y+ LG+LR++L R + Sbjct 560 NEFETEIELLSRLRHKHLVSLIGYCDEGGE--MCLIYDYMSLGTLREHLYNTKRPQLTWK 617 Query 999 QLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + L A G+ YLH IHRD+ N+LLD + + K+ DFGL+K P + + Sbjct 618 RRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILLDENWVAKVSDFGLSKTGPNMNGGH 677 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 V + PE + + SDV+SFGV L+E+L C P+ E + + Sbjct 678 -VTTVVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLFEVL--CARPALNPSLSKEQVSLG 734 Query 1116 QGQMTVLR---LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK-- 1170 M R L ++++ + +C + + C RPT +++ L+ Sbjct 735 DWAMNCKRKGTLEDIIDPNLKGKINPECLKKFADTAEKCLSDSGLDRPTMGDVLWNLEFA 794 Query 1171 -TVHEKYQGQ 1179 + E G Sbjct 795 LQLQETADGS 804 Score = 219 bits (557), Expect = 1e-57, Method: Composition-based stats. Identities = 58/291 (20%), Positives = 97/291 (33%), Gaps = 52/291 (18%) Query 579 LSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S + + + +G G VY+G + Sbjct 509 FSLSEIKHGTHNFDESNVIGVGGFGKVYKGVIDGG------------------------- 543 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +V +K +P+ F L+S++ H HL + G C G E ++ +Y+ G L Sbjct 544 TKVAIKKSNPNSEQGLNEFETEIELLSRLRHKHLVSLIGYCDEGGEMCLIYDYMSLGTLR 603 Query 697 VWLRR-ERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTS 752 L +R + ++ +A A L YL ++H +V NILL + Sbjct 604 EHLYNTKRPQLTWKRRLEIAIGAARGLHYLHTGAKYTIIHRDVKTTNILLDE-------N 656 Query 753 PFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 K+SD G+ G +L PE L+ D + FG L E Sbjct 657 WVAKVSDFGLSKTGPNMNGGHVTTVVKGSFGYLDPEYFR--RQQLTEKSDVYSFGVVLFE 714 Query 807 ICFDGEAPLQSRSPSEK-----EHFYQRQHRLPEPSCPQLA-TLTSQCLTY 851 + A S S + +R+ L + P L + +CL Sbjct 715 VLCARPALNPSLSKEQVSLGDWAMNCKRKGTLEDIIDPNLKGKINPECLKK 765 >sp|Q9FIU5|CRLK1_ARATH Calcium/calmodulin-regulated receptor-like kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CRLK1 PE=1 SV=1 Length=440 Score = 243 bits (619), Expect = 3e-69, Method: Composition-based stats. Identities = 73/326 (22%), Positives = 126/326 (39%), Gaps = 23/326 (7%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915 P + L+ + + K +G+G FG V Sbjct 72 SPVKSSKNGRSVWLEGFSKRSNVISASGILEYSYRDLQKATCNFTTLIGQGAFGPVYKAQ 131 Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 TGE+VAVK L D Q ++ E+ +L L+H +++ G C ++G+ Sbjct 132 -----MSTGEIVAVKVLATD-SKQGEKEFQTEVMLLGRLHHRNLVNLIGYCAEKGQH--M 183 Query 976 LVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNV 1029 L+ Y+ GSL +L + + A + G+ YLH IHRD+ + N+ Sbjct 184 LIYVYMSKGSLASHLYSEKHEPLSWDLRVYIALDVARGLEYLHDGAVPPVIHRDIKSSNI 243 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 LLD ++ DFGL++ +R + PE + F SDV+ FGV Sbjct 244 LLDQSMRARVADFGLSREEMVDKHAANIR----GTFGYLDPEYISTRTFTKKSDVYGFGV 299 Query 1090 TLYELLTHCDSSQSPPTKFLELIGI-AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148 L+EL+ ++P +EL+ + A + E+++ + EV Sbjct 300 LLFELIAG----RNPQQGLMELVELAAMNAEEKVGWEEIVDSRLDGRYDLQEVNEVAAFA 355 Query 1149 KNCWETEASFRPTFENLIPILKTVHE 1174 C RP +++ +L V + Sbjct 356 YKCISRAPRKRPNMRDIVQVLTRVIK 381 Score = 218 bits (556), Expect = 8e-61, Method: Composition-based stats. Identities = 62/326 (19%), Positives = 120/326 (37%), Gaps = 58/326 (18%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 + S+ + + + +GQG VY+ ++ Sbjct 102 EYSYRDLQKATCNFTTLIGQGAFGPVYKAQMSTGEI------------------------ 137 Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V +KVL F L+ ++ H +L + G C +++++ Y+ G L Sbjct 138 -VAVKVLATDSKQGEKEFQTEVMLLGRLHHRNLVNLIGYCAEKGQHMLIYVYMSKGSLAS 196 Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTS 752 L E+ H P++W ++ +A +A L YL + ++H ++ NILL + S Sbjct 197 HLYSEK-HEPLSWDLRVYIALDVARGLEYLHDGAVPPVIHRDIKSSNILLDQ-------S 248 Query 753 PFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 +++D G+ + + +L PE + + + D +GFG L E+ Sbjct 249 MRARVADFGLSREEMVDKHAANIRGTFGYLDPEYIST--RTFTKKSDVYGFGVLLFELIA 306 Query 810 DGEAPLQSRS--------------PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855 G P Q E+ + R ++A +C++ P + Sbjct 307 -GRNPQQGLMELVELAAMNAEEKVGWEEIVDSRLDGRYDLQEVNEVAAFAYKCISRAPRK 365 Query 856 RPSFRTILRDLTRLQPHNLADVLTVN 881 RP+ R I++ LTR+ N Sbjct 366 RPNMRDIVQVLTRVIKVRHCRKRQKN 391 >sp|P24062|IGF1R_RAT Insulin-like growth factor 1 receptor OS=Rattus norvegicus OX=10116 GN=Igf1r PE=2 SV=2 Length=1370 Score = 258 bits (660), Expect = 3e-69, Method: Composition-based stats. Identities = 92/312 (29%), Positives = 147/312 (47%), Gaps = 29/312 (9%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALK 933 D D + + R+LG+G FG V E VA+K + Sbjct 978 NPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVN 1037 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991 + R + E +++ H+++ G QG+ +L ++ME + G L+ YL Sbjct 1038 EAASMRERIEFLNEASVMKEFNCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSL 1095 Query 992 ----RHSI-----GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 +++ L++++ A +I +GMAYL+A ++HRDLAARN ++ D VKIGDF Sbjct 1096 RPEVENNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDF 1155 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 G+ + + E +YYR G PV W +PE LK+ F SDVWSFGV L+E+ T Sbjct 1156 GMTRDIYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIAT------ 1208 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 L ++ ++ + G L +PD CP ++ LM+ CW+ RP+F Sbjct 1209 --------LAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSF 1260 Query 1163 ENLIPILKTVHE 1174 +I +K E Sbjct 1261 LEIIGSIKDEME 1272 Score = 255 bits (651), Expect = 4e-68, Method: Composition-based stats. Identities = 100/488 (20%), Positives = 173/488 (35%), Gaps = 87/488 (18%) Query 425 RLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLI 484 +L +S+++ P D I GP+ RPE+ ++L +P LI Sbjct 813 KLGCSASNFVFARTMPA----EGADDIPGPVTWE-----PRPENSIFLKWPEPENPNGLI 863 Query 485 LTVAQR-SQAPDGMQSL----RLRKFPIEQQD-----------GAFVLEGWGR------- 521 L + + + RK+ + + A L G G Sbjct 864 LMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFF 923 Query 522 ------SFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLN 575 ++ + L AL +L + + + + A +P + Sbjct 924 YVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFS 983 Query 576 LSQL---SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 + + V +++IT LGQG+ VYEG + +P Sbjct 984 AADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEP---------------- 1027 Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 E RV +K ++ + + F AS+M + + H+ + GV +G +++ E + Sbjct 1028 ---ETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMT 1084 Query 692 HGPLDVWLRRERGHV---------PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 G L +LR R V ++ + +A ++A ++YL VH ++ RN ++ Sbjct 1085 RGDLKSYLRSLRPEVENNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV 1144 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMD 796 A +K+ D G+ + + + W++PE L G +T D Sbjct 1145 AE-------DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTHSD 1195 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPT 854 W FG L EI E P Q S + F L P+ L L C Y P Sbjct 1196 VWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPK 1255 Query 855 QRPSFRTI 862 RPSF I Sbjct 1256 MRPSFLEI 1263 >sp|Q9UM73|ALK_HUMAN ALK tyrosine kinase receptor OS=Homo sapiens OX=9606 GN=ALK PE=1 SV=3 Length=1620 Score = 259 bits (661), Expect = 3e-69, Method: Composition-based stats. Identities = 95/344 (28%), Positives = 142/344 (41%), Gaps = 34/344 (10%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 Q P ++ + + + S SD ++ + IR LG G FG+V Sbjct 1074 QSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEG 1133 Query 915 CYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 ND + VAVK L C Q + E I+ H++I++ G + Sbjct 1134 QVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRF 1193 Query 974 LQLVMEYVPLGSLRDYLPR--------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 + L E + G L+ +L S+ + LL A+ I G YL H+IHRD+A Sbjct 1194 ILL--ELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIA 1251 Query 1026 ARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082 ARN LL + KIGDFG+A+ + YYR PV W PE E F + Sbjct 1252 ARNCLLTCPGPGRVAKIGDFGMARDIYRA-SYYRKGGCAMLPVKWMPPEAFMEGIFTSKT 1310 Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 D WSFGV L+E+ + L + + + E + G R+ P CP Sbjct 1311 DTWSFGVLLWEIFS--------------LGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPG 1356 Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 VY +M CW+ + RP F ++ ++ Y Q P V + Sbjct 1357 PVYRIMTQCWQHQPEDRPNFAIILERIE-----YCTQDPDVINT 1395 Score = 254 bits (649), Expect = 9e-68, Method: Composition-based stats. Identities = 77/314 (25%), Positives = 120/314 (38%), Gaps = 40/314 (13%) Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 S V +K IT + LG G VYEG++ G +D PL Sbjct 1102 TSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQV---------SGMPNDPSPL------- 1145 Query 635 QELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +V +K L L F A ++S+ +H ++ GV ++ ++ E + G Sbjct 1146 ---QVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGG 1202 Query 694 PLDVWLRRERGHVP------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 L +LR R M + VA+ +A YLE + +H ++ RN LL Sbjct 1203 DLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLT---- 1258 Query 748 AEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFG 801 G K+ D G+ + + W+ PE G ++ D W FG Sbjct 1259 CPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGI--FTSKTDTWSFG 1316 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSF 859 L EI G P S+S E F R+ P +CP + + +QC ++P RP+F Sbjct 1317 VLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNF 1376 Query 860 RTILRDLTRLQPHN 873 IL + Sbjct 1377 AIILERIEYCTQDP 1390 >sp|Q6I5Q6|RK185_ORYSJ Receptor-like cytoplasmic kinase 185 OS=Oryza sativa subsp. japonica OX=39947 GN=RLCK185 PE=1 SV=1 Length=491 Score = 244 bits (622), Expect = 3e-69, Method: Composition-based stats. Identities = 77/297 (26%), Positives = 131/297 (44%), Gaps = 20/297 (7%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 ++ LGEG FG+V + G+ VAVK L + G Q + E+ +L L+ Sbjct 79 NFRQDCLLGEGGFGRVYKG-----HLENGQAVAVKQLDRN-GLQGNREFLVEVLMLSLLH 132 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEG 1010 H++++ G C D ++ LV E++PLGSL D+L + + + A +G Sbjct 133 HDNLVNLIGYCADGDQR--LLVYEFMPLGSLEDHLHDIPPDKEPLDWNTRMKIAAGAAKG 190 Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + +LH + I+RD + N+LL K+ DFGLAK P G + + V + Sbjct 191 LEFLHDKANPPVIYRDFKSSNILLGEGYHPKLSDFGLAKLGPVGDKTH-VSTRVMGTYGY 249 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVLR-LT 1125 APE + SDV+SFGV EL+T + + P L+ A+ R Sbjct 250 CAPEYAMTGQLTVKSDVYSFGVVFLELITGRKAIDNTKPLGEQNLVAWARPLFKDRRKFP 309 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV-HEKYQGQAP 1181 ++ + P + + + C + +A+ RP +++ L + + Y P Sbjct 310 KMADPLLAGRFPMRGLYQALAVAAMCLQEQAATRPFIGDVVTALSYLASQTYDPNTP 366 Score = 230 bits (587), Expect = 2e-64, Method: Composition-based stats. Identities = 71/358 (20%), Positives = 120/358 (34%), Gaps = 64/358 (18%) Query 559 SNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618 + I R A P + K Q LG+G VY+G L Sbjct 50 KDAFIPRDANGQPIAAHTFTFRELAAATKNFRQDCLLGEGGFGRVYKGHLENGQ------ 103 Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678 V +K LD + F ++S + H +L + G C Sbjct 104 -------------------AVAVKQLDRNGLQGNREFLVEVLMLSLLHHDNLVNLIGYCA 144 Query 679 RGPENIMVTEYVEHGPLDVWLRR---ERGHVPMAWKMVVAQQLASALSYLENK---NLVH 732 G + ++V E++ G L+ L ++ + +M +A A L +L +K +++ Sbjct 145 DGDQRLLVYEFMPLGSLEDHLHDIPPDKEPLDWNTRMKIAAGAAKGLEFLHDKANPPVIY 204 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG-LGALSREERV-----ERIPWLAPECLPG 786 + NILL G KLSD G+ LG + + V + APE Sbjct 205 RDFKSSNILL-------GEGYHPKLSDFGLAKLGPVGDKTHVSTRVMGTYGYCAPEYAMT 257 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ------RQHRLPEPSCPQ 840 G L+ D + FG LE+ +A ++ E+ + + P+ + P Sbjct 258 G--QLTVKSDVYSFGVVFLELITGRKAIDNTKPLGEQNLVAWARPLFKDRRKFPKMADPL 315 Query 841 LA------------TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 LA + + CL + RP ++ L+ L V Sbjct 316 LAGRFPMRGLYQALAVAAMCLQEQAATRPFIGDVVTALSYLASQTYDPNTPVQHSRSN 373 >sp|Q1PDW3|LIPG1_ARATH Receptor-like kinase LIP1 OS=Arabidopsis thaliana OX=3702 GN=LIP1 PE=1 SV=1 Length=636 Score = 248 bits (633), Expect = 3e-69, Method: Composition-based stats. Identities = 88/370 (24%), Positives = 141/370 (38%), Gaps = 24/370 (6%) Query 833 LPEPSCPQLATLTSQ---CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 + P + S+ C T E R + P Sbjct 3 IMMNCFPCFTSQKSRNAPCTTNETNDDNVEHDEFRPPVVATTKRTEEREPAEQQPPVKTF 62 Query 890 TVFH----KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 + ++ LGEG FG+V Y T TG++VAVK L G + Sbjct 63 NFRELATATKNFRQECLLGEGGFGRV----YKGTLQSTGQLVAVKQLDKH-GLHGNKEFL 117 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQL 1000 E+ L L H +++K G C D ++ LV EYV GSL+D+L + + Sbjct 118 AEVLSLAKLEHPNLVKLIGYCADGDQR--LLVFEYVSGGSLQDHLYEQKPGQKPMDWITR 175 Query 1001 LLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + A +G+ YLH + I+RDL A N+LLD + K+ DFGL P + + Sbjct 176 MKIAFGAAQGLDYLHDKVTPAVIYRDLKASNILLDAEFYPKLCDFGLHNLEPGTGDSLFL 235 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQ 1116 + APE + SDV+SFGV L EL+T + + P L+ AQ Sbjct 236 SSRVMDTYGYSAPEYTRGDDLTVKSDVYSFGVVLLELITGRRAIDTTKPNDEQNLVAWAQ 295 Query 1117 G-QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 R ++ + R ++ + + C + E + RP +++ L + Sbjct 296 PIFKDPKRYPDMADPLLRKNFSERGLNQAVAITSMCLQEEPTARPLISDVMVALSFLSMS 355 Query 1176 YQGQAPSVFS 1185 + P+ Sbjct 356 TEDGIPATVP 365 Score = 236 bits (603), Expect = 4e-65, Method: Composition-based stats. Identities = 85/414 (21%), Positives = 139/414 (34%), Gaps = 67/414 (16%) Query 523 FPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFH 582 F S + A + R + + + + +T N +L+ Sbjct 11 FTSQKSRNAPCTTNETNDDNVEHDEFRPPVVATTKRTEEREPAEQQPPVKTFNFRELAT- 69 Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 K Q LG+G VY+G L+ G V +K Sbjct 70 --ATKNFRQECLLGEGGFGRVYKGTLQSTGQ------------------------LVAVK 103 Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 LD F ++++ H +L + G C G + ++V EYV G L L + Sbjct 104 QLDKHGLHGNKEFLAEVLSLAKLEHPNLVKLIGYCADGDQRLLVFEYVSGGSLQDHLYEQ 163 Query 703 R-GHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIK 756 + G PM W +M +A A L YL +K +++ ++ NILL + K Sbjct 164 KPGQKPMDWITRMKIAFGAAQGLDYLHDKVTPAVIYRDLKASNILLD-------AEFYPK 216 Query 757 LSDPGV-------GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 L D G+ G ++ + APE G + L+ D + FG LLE+ Sbjct 217 LCDFGLHNLEPGTGDSLFLSSRVMDTYGYSAPEYTRG--DDLTVKSDVYSFGVVLLELIT 274 Query 810 DGEAPLQSRSPSEKEHFYQRQ------HRLPEPSCPQLAT------------LTSQCLTY 851 A ++ E+ Q R P+ + P L +TS CL Sbjct 275 GRRAIDTTKPNDEQNLVAWAQPIFKDPKRYPDMADPLLRKNFSERGLNQAVAITSMCLQE 334 Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 EPT RP ++ L+ L + P D ++ + Sbjct 335 EPTARPLISDVMVALSFLSMSTEDGIPATVPMESFRDKSMSIALSRHGSCSVTP 388 >sp|Q9ZR08|Y4230_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At4g03230 OS=Arabidopsis thaliana OX=3702 GN=At4g03230 PE=3 SV=3 Length=852 Score = 253 bits (645), Expect = 4e-69, Method: Composition-based stats. Identities = 77/286 (27%), Positives = 121/286 (42%), Gaps = 17/286 (6%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 + LG+G FG V + + +AVK L C Q +K E+ ++ Sbjct 527 YATSNFSNANKLGQGGFGPVYKGMFPG-----DQEIAVKRLSR-CSGQGLEEFKNEVVLI 580 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI----GLAQLLLFAQQI 1007 L H ++++ G C EK L+ EY+P SL ++ + I Sbjct 581 AKLQHRNLVRLLGYCVAGEEK--LLLYEYMPHKSLDFFIFDRKLCQRLDWKMRCNIILGI 638 Query 1008 CEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 G+ YLH IHRDL N+LLD + KI DFGLA+ G E Sbjct 639 ARGLLYLHQDSRLRIIHRDLKTSNILLDEEMNPKISDFGLARIFG-GSETSANTNRVVGT 697 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLR 1123 + +PE E F + SDV+SFGV + E ++ + P K L L+G A R Sbjct 698 YGYMSPEYALEGLFSFKSDVFSFGVVVIETISGKRNTGFHEPEKSLSLLGHAWDLWKAER 757 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 ELL++ + + + ++ C + + + RPT N++ +L Sbjct 758 GIELLDQALQESCETEGFLKCLNVGLLCVQEDPNDRPTMSNVVFML 803 Score = 225 bits (573), Expect = 1e-59, Method: Composition-based stats. Identities = 52/284 (18%), Positives = 97/284 (34%), Gaps = 48/284 (17%) Query 565 RGARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 R + + +++ + + + LGQG VY+G + Sbjct 506 RFKQDDSQGIDVPSFELETILYATSNFSNANKLGQGGFGPVYKGMFPGDQ---------- 555 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 + +K L F L++++ H +L + G CV G E Sbjct 556 ---------------EIAVKRLSRCSGQGLEEFKNEVVLIAKLQHRNLVRLLGYCVAGEE 600 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENK---NLVHGNVCG 737 +++ EY+ H LD ++ + + WKM + +A L YL ++H ++ Sbjct 601 KLLLYEYMPHKSLDFFIFDRKLCQRLDWKMRCNIILGIARGLLYLHQDSRLRIIHRDLKT 660 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSL 791 NILL K+SD G+ + + V +++PE G Sbjct 661 SNILLDEE-------MNPKISDFGLARIFGGSETSANTNRVVGTYGYMSPEYALEGL--F 711 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 S D + FG ++E G+ P + L + Sbjct 712 SFKSDVFSFGVVVIETIS-GKRNTGFHEPEKSLSLLGHAWDLWK 754 >sp|Q60751|IGF1R_MOUSE Insulin-like growth factor 1 receptor OS=Mus musculus OX=10090 GN=Igf1r PE=1 SV=3 Length=1373 Score = 258 bits (659), Expect = 4e-69, Method: Composition-based stats. Identities = 92/313 (29%), Positives = 148/313 (47%), Gaps = 30/313 (10%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALK 933 D D + + R+LG+G FG V E VA+K + Sbjct 978 NPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVN 1037 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991 + R + E +++ H+++ G QG+ +L ++ME + G L+ YL Sbjct 1038 EAASMRERIEFLNEASVMKEFNCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSYLRSL 1095 Query 992 -----RHSI-----GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 ++++ L++++ A +I +GMAYL+A ++HRDLAARN ++ D VKIGD Sbjct 1096 RPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGD 1155 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FG+ + + E +YYR G PV W +PE LK+ F SDVWSFGV L+E+ T Sbjct 1156 FGMTRDIYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIAT----- 1209 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 L ++ ++ + G L +PD CP ++ LM+ CW+ RP+ Sbjct 1210 ---------LAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPS 1260 Query 1162 FENLIPILKTVHE 1174 F +I +K E Sbjct 1261 FLEIIGSIKDEME 1273 Score = 254 bits (650), Expect = 6e-68, Method: Composition-based stats. Identities = 100/489 (20%), Positives = 173/489 (35%), Gaps = 88/489 (18%) Query 425 RLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLI 484 +L +S+++ P D I GP+ RPE+ ++L +P LI Sbjct 813 KLGCSASNFVFARTMPA----EGADDIPGPVTWE-----PRPENSIFLKWPEPENPNGLI 863 Query 485 LTVAQR-SQAPDGMQSL----RLRKFPIEQQD-----------GAFVLEGWGR------- 521 L + + + RK+ + + A L G G Sbjct 864 LMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFF 923 Query 522 ------SFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLN 575 ++ + L AL +L + + + + A +P + Sbjct 924 YVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFS 983 Query 576 LSQL---SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 + + V +++IT LGQG+ VYEG + +P Sbjct 984 AADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEP---------------- 1027 Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 E RV +K ++ + + F AS+M + + H+ + GV +G +++ E + Sbjct 1028 ---ETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMT 1084 Query 692 HGPLDVWLRRERGHV----------PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 G L +LR R V ++ + +A ++A ++YL VH ++ RN + Sbjct 1085 RGDLKSYLRSLRPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCM 1144 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAM 795 +A +K+ D G+ + + + W++PE L G +T Sbjct 1145 VAE-------DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTTHS 1195 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEP 853 D W FG L EI E P Q S + F L P+ L L C Y P Sbjct 1196 DVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNP 1255 Query 854 TQRPSFRTI 862 RPSF I Sbjct 1256 KMRPSFLEI 1264 >sp|Q01973|ROR1_HUMAN Inactive tyrosine-protein kinase transmembrane receptor ROR1 OS=Homo sapiens OX=9606 GN=ROR1 PE=1 SV=2 Length=937 Score = 254 bits (649), Expect = 5e-69, Method: Composition-based stats. Identities = 82/291 (28%), Positives = 135/291 (46%), Gaps = 35/291 (12%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 + +LGE FGK+ ++VA+K LK PQ + ++QE ++ L+H + Sbjct 475 FMEELGECAFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPN 534 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------------------RHSIGLAQL 1000 I+ G E+ + ++ EY+ G L ++L + S+ Sbjct 535 IVCLLGAVTQ--EQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDF 592 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 L A QI GM YL + ++H+DLAARN+L+ VKI D GL++ + +YYRV+ Sbjct 593 LHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIY-SADYYRVQSK 651 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 P+ W PE + KF SD+WSFGV L+E+ + + Sbjct 652 SLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQ--------------PYYGFS 697 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + E++ + + LP + CP +Y LM CW S RP F+++ L++ Sbjct 698 NQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRS 748 Score = 237 bits (604), Expect = 2e-63, Method: Composition-based stats. Identities = 70/312 (22%), Positives = 120/312 (38%), Gaps = 54/312 (17%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 + + + + LG+ +Y+G L +PG D Q Sbjct 461 PKSKAKELPLSAVRFMEELGECAFGKIYKGHL------------------YLPGMDHAQ- 501 Query 637 LRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K L ++ F + ASLM+++ H ++ + G + M+ EY+ G L Sbjct 502 -LVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDL 560 Query 696 DVWLRRERGHVPMAWK----------------MVVAQQLASALSYLENKNLVHGNVCGRN 739 +L H + + +A Q+A+ + YL + VH ++ RN Sbjct 561 HEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARN 620 Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLST 793 IL+ G +K+SD G+ S + I W+ PE + G S+ Sbjct 621 ILI-------GEQLHVKISDLGLSREIYSADYYRVQSKSLLPIRWMPPEAIMYG--KFSS 671 Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE--PSCPQLATLTSQCLTY 851 D W FG L EI G P S E +++ LP P++ +L ++C Sbjct 672 DSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNE 731 Query 852 EPTQRPSFRTIL 863 P++RP F+ I Sbjct 732 IPSRRPRFKDIH 743 >sp|O65476|CRK16_ARATH Putative cysteine-rich receptor-like protein kinase 16 OS=Arabidopsis thaliana OX=3702 GN=CRK16 PE=3 SV=2 Length=662 Score = 248 bits (634), Expect = 5e-69, Method: Composition-based stats. Identities = 73/286 (26%), Positives = 109/286 (38%), Gaps = 18/286 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 +K LG G FG+V + G VAVK L G Q +K E+ ++ L Sbjct 333 NNFQKSNKLGHGGFGEVFKGTF-----PNGTEVAVKRLSKISG-QGEEEFKNEVLLVAKL 386 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL----RDYLPRHSIGLAQLLLFAQQICEG 1010 H ++++ G + EK LV EY+P SL D+ R + + + G Sbjct 387 QHRNLVRLLGFSVEGEEK--ILVYEYMPNKSLDYFLFDHRRRGQLDWRTRYNIIRGVTRG 444 Query 1011 MAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH IHRDL A N+LLD D KI DFG+A+ + Sbjct 445 ILYLHQDSRLTIIHRDLKAGNILLDVDMNPKIADFGVARNFRVDQTEATT-GRVVGTFGY 503 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLT 1125 PE + +F SDV+SFGV + E++ S L+ Sbjct 504 MPPEYVANGQFSMKSDVYSFGVLILEIIVGKKSSSFHEIDGSVGNLVTYVWRLWNNESFL 563 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 EL++ H+ C + + RPT + +L Sbjct 564 ELVDPAMGESYDKDEVIRCIHISLLCVQENPADRPTMSTVFQMLTN 609 Score = 232 bits (592), Expect = 2e-63, Method: Composition-based stats. Identities = 59/324 (18%), Positives = 105/324 (32%), Gaps = 65/324 (20%) Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 T Q F ++ + + LG G V++G Sbjct 317 TSGSLQFDFKAIEAATNNFQKSNKLGHGGFGEVFKGT----------------------- 353 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 V +K L F L++++ H +L + G V G E I+V EY+ Sbjct 354 --FPNGTEVAVKRLSKISGQGEEEFKNEVLLVAKLQHRNLVRLLGFSVEGEEKILVYEYM 411 Query 691 EHGPLDVWL--RRERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745 + LD +L R RG + + + + + + YL + ++H ++ NILL Sbjct 412 PNKSLDYFLFDHRRRGQLDWRTRYNIIRGVTRGILYLHQDSRLTIIHRDLKAGNILLD-- 469 Query 746 GLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWG 799 K++D GV + V ++ PE + G S D + Sbjct 470 -----VDMNPKIADFGVARNFRVDQTEATTGRVVGTFGYMPPEYVANG--QFSMKSDVYS 522 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC------PQLAT---------- 843 FG +LEI ++ + RL P + Sbjct 523 FGVLILEIIVGKKSSSFHEIDGSVGNLVTYVWRLWNNESFLELVDPAMGESYDKDEVIRC 582 Query 844 --LTSQCLTYEPTQRPSFRTILRD 865 ++ C+ P RP+ T+ + Sbjct 583 IHISLLCVQENPADRPTMSTVFQM 606 >sp|Q63474|DDR1_RAT Epithelial discoidin domain-containing receptor 1 OS=Rattus norvegicus OX=10116 GN=Ddr1 PE=2 SV=1 Length=910 Score = 253 bits (647), Expect = 5e-69, Method: Composition-based stats. Identities = 99/317 (31%), Positives = 143/317 (45%), Gaps = 45/317 (14%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD------------PTNDGTGEMVAVKALKA 934 F + L+ LGEG FG+V L + G +VAVK L+ Sbjct 597 PPRVDFPRSRLRFKEKLGEGQFGEVHLCEVEDPQDLVTSDFPISVQKGHPLLVAVKILRP 656 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993 D R+ + +E+ I+ L +II+ G C + L ++ +Y+ G L +L H Sbjct 657 DATKNARNDFLKEVKIMSRLKDLNIIRLLGVCVQ--DDPLCMITDYMENGDLNQFLSAHQ 714 Query 994 -------------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034 +I LL QI GM YL +++HRDLA RN L+ + Sbjct 715 LENKVTQGLPGDRESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLVGEN 774 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 +KI DFG+++ + G +YYRV+ P+ W A EC+ KF ASDVW+FGVTL+E+ Sbjct 775 FTIKIADFGMSRNLYAG-DYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEV 833 Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER--LPRPDKCPCEVYHLMKNCW 1152 L C +S P L + + R ++G + L RP CP +Y LM CW Sbjct 834 LMLC---RSQPFGQLTDEQVIENAGEFFR-----DQGRQVYLSRPPACPQTLYELMLRCW 885 Query 1153 ETEASFRPTFENLIPIL 1169 E RP F L L Sbjct 886 SREPEQRPPFSQLHRFL 902 Score = 227 bits (578), Expect = 3e-60, Method: Composition-based stats. Identities = 74/316 (23%), Positives = 123/316 (39%), Gaps = 52/316 (16%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + + LG+G V+ + E+ + +G L V +K+L Sbjct 603 PRSRLRFKEKLGEGQFGEVH--------LCEVEDPQDLVTSDFPISVQKGHPLLVAVKIL 654 Query 645 DPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 P A F + +MS++ ++ + GVCV+ M+T+Y+E+G L+ +L + Sbjct 655 RPDATKNARNDFLKEVKIMSRLKDLNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQ 714 Query 704 GHVPMAW------------------KMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 + + V Q+AS + YL N VH ++ RN L+ Sbjct 715 LENKVTQGLPGDRESDQGPTISYPMLLHVGAQIASGMRYLATLNFVHRDLATRNCLV--- 771 Query 746 GLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWG 799 G + IK++D G+ + + V I W+A EC+ G +TA D W Sbjct 772 ----GENFTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMG--KFTTASDVWA 825 Query 800 FGATLLEI-CFDGEAPLQSRSPSEKE----HFYQRQHRL-----PEPSCPQLATLTSQCL 849 FG TL E+ P + + F++ Q R P L L +C Sbjct 826 FGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQTLYELMLRCW 885 Query 850 TYEPTQRPSFRTILRD 865 + EP QRP F + R Sbjct 886 SREPEQRPPFSQLHRF 901 >sp|Q9NYL2|M3K20_HUMAN Mitogen-activated protein kinase kinase kinase 20 OS=Homo sapiens OX=9606 GN=MAP3K20 PE=1 SV=3 Length=800 Score = 251 bits (641), Expect = 6e-69, Method: Composition-based stats. Identities = 82/283 (29%), Positives = 132/283 (47%), Gaps = 40/283 (14%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 + + G G FG V + + VAVK L ++E +IL L H Sbjct 17 QFFENCGGGSFGSVYRAKWISQDK----EVAVKKLLK---------IEKEAEILSVLSHR 63 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYL 1014 +II++ G + + +V EY LGSL DY+ + + + ++ +A + +GM YL Sbjct 64 NIIQFYGVILEP--PNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYL 121 Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 H + IHRDL +RNV++ D ++KI DFG ++ + W APE Sbjct 122 HMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN-----HTTHMSLVGTFPWMAPE 176 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 ++ D +S+GV L+E+LT P K LE + +A ++E+ Sbjct 177 VIQSLPVSETCDTYSYGVVLWEMLTR-----EVPFKGLEGLQVAWL---------VVEKN 222 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 ERL P CP L+ CWE +A RP+F+ +I IL+++ Sbjct 223 ERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSN 265 Score = 211 bits (537), Expect = 2e-55, Method: Composition-based stats. Identities = 65/334 (19%), Positives = 124/334 (37%), Gaps = 51/334 (15%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 SF ++ ++ + G G+ +VY + Q+ V Sbjct 7 SFVQIKFDDLQFFENCGGGSFGSVYRAKWI------------------------SQDKEV 42 Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +K L L + A ++S +SH ++ +GV + P +VTEY G L ++ Sbjct 43 AVKKL--------LKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYI 94 Query 700 RRERG-HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFI 755 R + M M A +A + YL + ++H ++ RN+++A G+ + Sbjct 95 NSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV-------L 147 Query 756 KLSDPGVGLGALSREER--VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 K+ D G V PW+APE + + +S D + +G L E+ E Sbjct 148 KICDFGASRFHNHTTHMSLVGTFPWMAPEVIQ--SLPVSETCDTYSYGVVLWEMLTR-EV 204 Query 814 PLQSRSPSEKEHF---YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P + + + +P A L QC + +RPSF+ I+ L + Sbjct 205 PFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMS 264 Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 + ++ + L++++ L Sbjct 265 NDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLE 298 >sp|Q9LYN8|EMS1_ARATH Leucine-rich repeat receptor protein kinase EMS1 OS=Arabidopsis thaliana OX=3702 GN=EMS1 PE=1 SV=1 Length=1192 Score = 256 bits (655), Expect = 6e-69, Method: Composition-based stats. Identities = 72/288 (25%), Positives = 122/288 (42%), Gaps = 20/288 (7%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 + K +G+G FG V C + VAVK L ++ Q + E++ L + Sbjct 915 DHFSKKNIIGDGGFGTVYKACLPGE-----KTVAVKKL-SEAKTQGNREFMAEMETLGKV 968 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICE 1009 H +++ G C EK LV EY+ GSL +L + + ++ L A Sbjct 969 KHPNLVSLLGYCSFSEEK--LLVYEYMVNGSLDHWLRNQTGMLEVLDWSKRLKIAVGAAR 1026 Query 1010 GMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G+A+LH H IHRD+ A N+LLD D K+ DFGLA+ + + V Sbjct 1027 GLAFLHHGFIPHIIHRDIKASNILLDGDFEPKVADFGLARLISACESH--VSTVIAGTFG 1084 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRL 1124 + PE + + DV+SFGV L EL+T + ++ L+G A ++ + Sbjct 1085 YIPPEYGQSARATTKGDVYSFGVILLELVTGKEPTGPDFKESEGGNLVGWAIQKINQGKA 1144 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 ++++ + + C + RP +++ LK + Sbjct 1145 VDVIDPLLVSVALKNSQLRLLQIAMLCLAETPAKRPNMLDVLKALKEI 1192 Score = 222 bits (566), Expect = 7e-58, Method: Composition-based stats. Identities = 61/307 (20%), Positives = 108/307 (35%), Gaps = 63/307 (21%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 ++ + +G G VY+ L E V +K L Sbjct 913 ATDHFSKKNIIGDGGFGTVYKACLPG-------------------------EKTVAVKKL 947 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + F + +V H +L + G C E ++V EY+ +G LD WLR + G Sbjct 948 SEAKTQGNREFMAEMETLGKVKHPNLVSLLGYCSFSEEKLLVYEYMVNGSLDHWLRNQTG 1007 Query 705 ---HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + + ++ +A A L++L + +++H ++ NILL K++ Sbjct 1008 MLEVLDWSKRLKIAVGAARGLAFLHHGFIPHIIHRDIKASNILLD-------GDFEPKVA 1060 Query 759 DPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 D G+ + E V ++ PE G + +T D + FG LLE+ E Sbjct 1061 DFGLARLISACESHVSTVIAGTFGYIPPEY--GQSARATTKGDVYSFGVILLELVTGKEP 1118 Query 814 PLQSRSPSEKEHFYQR------QHRLPEPSCPQLAT------------LTSQCLTYEPTQ 855 SE + Q + + P L + + CL P + Sbjct 1119 TGPDFKESEGGNLVGWAIQKINQGKAVDVIDPLLVSVALKNSQLRLLQIAMLCLAETPAK 1178 Query 856 RPSFRTI 862 RP+ + Sbjct 1179 RPNMLDV 1185 >sp|Q9ESL4|M3K20_MOUSE Mitogen-activated protein kinase kinase kinase 20 OS=Mus musculus OX=10090 GN=Map3k20 PE=1 SV=1 Length=802 Score = 251 bits (641), Expect = 6e-69, Method: Composition-based stats. Identities = 82/283 (29%), Positives = 132/283 (47%), Gaps = 40/283 (14%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 + + G G FG V + + VAVK L ++E +IL L H Sbjct 17 QFFENCGGGSFGSVYRAKWISQDK----EVAVKKLLK---------IEKEAEILSVLSHR 63 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYL 1014 +II++ G + + +V EY LGSL DY+ + + + ++ +A + +GM YL Sbjct 64 NIIQFYGVILEP--PNYGIVTEYASLGSLYDYINSNRSEEMDMEHIMTWATDVAKGMHYL 121 Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 H + IHRDL +RNV++ D ++KI DFG ++ + W APE Sbjct 122 HMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN-----HTTHMSLVGTFPWMAPE 176 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 ++ D +S+GV L+E+LT P K LE + +A ++E+ Sbjct 177 VIQSLPVSETCDTYSYGVVLWEMLTR-----EVPFKGLEGLQVAWL---------VVEKN 222 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 ERL P CP L+ CWE +A RP+F+ +I IL+++ Sbjct 223 ERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSN 265 Score = 209 bits (533), Expect = 5e-55, Method: Composition-based stats. Identities = 65/334 (19%), Positives = 124/334 (37%), Gaps = 51/334 (15%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 SF ++ ++ + G G+ +VY + Q+ V Sbjct 7 SFVQIKFDDLQFFENCGGGSFGSVYRAKWI------------------------SQDKEV 42 Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +K L L + A ++S +SH ++ +GV + P +VTEY G L ++ Sbjct 43 AVKKL--------LKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYI 94 Query 700 RRERG-HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFI 755 R + M M A +A + YL + ++H ++ RN+++A G+ + Sbjct 95 NSNRSEEMDMEHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGV-------L 147 Query 756 KLSDPGVGLGALSREER--VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 K+ D G V PW+APE + + +S D + +G L E+ E Sbjct 148 KICDFGASRFHNHTTHMSLVGTFPWMAPEVIQ--SLPVSETCDTYSYGVVLWEMLTR-EV 204 Query 814 PLQSRSPSEKEHF---YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P + + + +P A L QC + +RPSF+ I+ L + Sbjct 205 PFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMS 264 Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 + ++ + L++++ L Sbjct 265 NDTNLPDQCNSFLHNKAEWRCEIEATLERLKKLE 298 >sp|Q9FID8|Y5900_ARATH Putative receptor-like protein kinase At5g39000 OS=Arabidopsis thaliana OX=3702 GN=At5g39000 PE=3 SV=1 Length=873 Score = 253 bits (645), Expect = 7e-69, Method: Composition-based stats. Identities = 76/294 (26%), Positives = 126/294 (43%), Gaps = 20/294 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V Y DG +VAVK L+ Q ++ E+++L L H H++ Sbjct 524 IGVGGFGSV----YKGQIDGGATLVAVKRLEI-TSNQGAKEFETELEMLSKLRHVHLVSL 578 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------SIGLAQLLLFAQQICEGMAYLHA 1016 G C++ E + LV EY+P G+L+D+L R + + L G+ YLH Sbjct 579 IGYCDEDNE--MVLVYEYMPHGTLKDHLFRRDKTSDPPLSWKRRLEICIGAARGLQYLHT 636 Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRD+ N+LLD + + K+ DFGL++ P V + PE Sbjct 637 GAKYTIIHRDIKTTNILLDENFVTKVSDFGLSRVGPTSASQTHVSTVVKGTFGYLDPEYY 696 Query 1074 KEYKFYYASDVWSFGVTLYELL-THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + SDV+SFGV L E+L QS P + +LI + + ++++ Sbjct 697 RRQVLTEKSDVYSFGVVLLEVLCCRPIRMQSVPPEQADLIRWVKSNYRRGTVDQIIDSDL 756 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK---TVHEKYQGQAPSV 1183 + + C + RP +++ L+ +HE + + +V Sbjct 757 SADITSTSLEKFCEIAVRCVQDRGMERPPMNDVVWALEFALQLHETAKKKNDNV 810 Score = 223 bits (568), Expect = 4e-59, Method: Composition-based stats. Identities = 67/348 (19%), Positives = 123/348 (35%), Gaps = 70/348 (20%) Query 550 CCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGR 607 C LP +++N + A++ P L + S + + +G G +VY+G+ Sbjct 481 CPLPHGTDSTN---TKPAKSLPADL-CRRFSIFEIKSATNDFEDKLIIGVGGFGSVYKGQ 536 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667 + G V +K L+ + + A F ++S++ H Sbjct 537 I------------------------DGGATLVAVKRLEITSNQGAKEFETELEMLSKLRH 572 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG--HVPMAW--KMVVAQQLASALS 723 HL + G C E ++V EY+ HG L L R P++W ++ + A L Sbjct 573 VHLVSLIGYCDEDNEMVLVYEYMPHGTLKDHLFRRDKTSDPPLSWKRRLEICIGAARGLQ 632 Query 724 YLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV------- 773 YL ++H ++ NILL + K+SD G+ + + Sbjct 633 YLHTGAKYTIIHRDIKTTNILLDE-------NFVTKVSDFGLSRVGPTSASQTHVSTVVK 685 Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ--RQH 831 +L PE L+ D + FG LLE+ +QS P + + + Sbjct 686 GTFGYLDPEYYRRQV--LTEKSDVYSFGVVLLEVLCCRPIRMQSVPPEQADLIRWVKSNY 743 Query 832 R---------------LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 R + S + + +C+ +RP ++ Sbjct 744 RRGTVDQIIDSDLSADITSTSLEKFCEIAVRCVQDRGMERPPMNDVVW 791 >sp|C0LGU1|Y5374_ARATH Probable LRR receptor-like serine/threonine-protein kinase At5g37450 OS=Arabidopsis thaliana OX=3702 GN=At5g37450 PE=1 SV=1 Length=959 Score = 254 bits (648), Expect = 7e-69, Method: Composition-based stats. Identities = 72/280 (26%), Positives = 120/280 (43%), Gaps = 22/280 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G +GKV G +VAVK Q + + EI++L L+H +++ Sbjct 637 IGRGGYGKVYKGHLPG-----GLVVAVKR-AEQGSLQGQKEFFTEIELLSRLHHRNLVSL 690 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 G C+ +GE+ LV EY+P GSL+D L R + LA L A G+ YLH + Sbjct 691 LGYCDQKGEQ--MLVYEYMPNGSLQDALSARFRQPLSLALRLRIALGSARGILYLHTEAD 748 Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAV---PEGHEYYRVREDGDSPVFWYAPECL 1073 IHRD+ N+LLD+ K+ DFG++K + G + V + PE Sbjct 749 PPIIHRDIKPSNILLDSKMNPKVADFGISKLIALDGGGVQRDHVTTIVKGTPGYVDPEYY 808 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 ++ SDV+S G+ E+LT P + ++ + +++R Sbjct 809 LSHRLTEKSDVYSLGIVFLEILTGMR----PISHGRNIVREVNEACDAGMMMSVIDRSM- 863 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 ++C L C + RP ++ L+ ++ Sbjct 864 GQYSEECVKRFMELAIRCCQDNPEARPWMLEIVRELENIY 903 Score = 227 bits (578), Expect = 5e-60, Method: Composition-based stats. Identities = 66/343 (19%), Positives = 117/343 (34%), Gaps = 69/343 (20%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 P P N+ ++G N ++L + LS +G+G VY+G L Sbjct 605 PLPKPPMNMESVKG-------YNFTELDS---ATSSFSDLSQIGRGGYGKVYKGHLPGG- 653 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672 L V +K + F+ L+S++ H +L Sbjct 654 ------------------------LVVAVKRAEQGSLQGQKEFFTEIELLSRLHHRNLVS 689 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLE---NK 728 + G C + E ++V EY+ +G L L R + +A ++ +A A + YL + Sbjct 690 LLGYCDQKGEQMLVYEYMPNGSLQDALSARFRQPLSLALRLRIALGSARGILYLHTEADP 749 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERV----ERIPW 778 ++H ++ NILL K++D G+ G + R+ + Sbjct 750 PIIHRDIKPSNILLDSK-------MNPKVADFGISKLIALDGGGVQRDHVTTIVKGTPGY 802 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS-PSEKEHFYQRQHRL---- 833 + PE ++ L+ D + G LEI R+ E + Sbjct 803 VDPEYYL--SHRLTEKSDVYSLGIVFLEILTGMRPISHGRNIVREVNEACDAGMMMSVID 860 Query 834 ------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 E + L +C P RP I+R+L + Sbjct 861 RSMGQYSEECVKRFMELAIRCCQDNPEARPWMLEIVRELENIY 903 >sp|O65483|CRK24_ARATH Cysteine-rich receptor-like protein kinase 24 OS=Arabidopsis thaliana OX=3702 GN=CRK24 PE=3 SV=2 Length=636 Score = 247 bits (631), Expect = 8e-69, Method: Composition-based stats. Identities = 76/299 (25%), Positives = 113/299 (38%), Gaps = 18/299 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 + LG G FG+V + G VAVK L G Q +K E+ ++ L Sbjct 310 CNFHNVNKLGHGGFGEVYKGTF-----PNGTEVAVKRLSKTSG-QGEEEFKNEVFLVAKL 363 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEG 1010 H +++K G EK LV E++P SL +L + + + I G Sbjct 364 QHRNLVKLLGYAVKGDEK--ILVYEFLPNKSLDHFLFDPVKKGQLDWTRRYNIINGITRG 421 Query 1011 MAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH IHRDL A N+LLD D KI DFG+A+ + + Sbjct 422 IVYLHQDSRLTIIHRDLKAGNILLDADMNPKIVDFGVARNFRVDQTEATTAR-VVGTIGY 480 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK--FLELIGIAQGQMTVLRLT 1125 PE + +F SDV+SFGV + E++ +S T L+ L Sbjct 481 MPPEYVTNGQFSTKSDVYSFGVLILEIIGGKKNSSINETDGSISNLVTYVWRLWNNEPLL 540 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 EL++ H+ C + + RPT + +L P F Sbjct 541 ELVDAPMGENYDRNEVIRCIHIGLLCVQENPADRPTMSTVFHMLTNTSITLHVPQPPGF 599 Score = 220 bits (561), Expect = 1e-59, Method: Composition-based stats. Identities = 61/350 (17%), Positives = 108/350 (31%), Gaps = 65/350 (19%) Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 T Q F ++ ++ LG G VY+G Sbjct 294 TSGSLQFEFKAIEAATCNFHNVNKLGHGGFGEVYKGT----------------------- 330 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 V +K L + F L++++ H +L + G V+G E I+V E++ Sbjct 331 --FPNGTEVAVKRLSKTSGQGEEEFKNEVFLVAKLQHRNLVKLLGYAVKGDEKILVYEFL 388 Query 691 EHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745 + LD +L ++G + + + + + YL + ++H ++ NILL Sbjct 389 PNKSLDHFLFDPVKKGQLDWTRRYNIINGITRGIVYLHQDSRLTIIHRDLKAGNILLD-- 446 Query 746 GLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWG 799 K+ D GV + V I ++ PE + G ST D + Sbjct 447 -----ADMNPKIVDFGVARNFRVDQTEATTARVVGTIGYMPPEYVTNG--QFSTKSDVYS 499 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP------------------EPSCPQL 841 FG +LEI + + + + RL + Sbjct 500 FGVLILEIIGGKKNSSINETDGSISNLVTYVWRLWNNEPLLELVDAPMGENYDRNEVIRC 559 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV 891 + C+ P RP+ T+ LT P Sbjct 560 IHIGLLCVQENPADRPTMSTVFHMLTNTSITLHVPQPPGFVFRVRFKPNP 609 >sp|Q9XEC7|CRK37_ARATH Cysteine-rich receptor-like protein kinase 37 OS=Arabidopsis thaliana OX=3702 GN=CRK37 PE=3 SV=1 Length=646 Score = 247 bits (631), Expect = 8e-69, Method: Composition-based stats. Identities = 71/321 (22%), Positives = 125/321 (39%), Gaps = 21/321 (7%) Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922 + + + V LG+G FG V Sbjct 311 RKQSHTIINDVFDSNNGQSMLRFDLRMIVTATNNFSLENKLGQGGFGSVYKGIL-----P 365 Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982 +G+ +AVK L+ G +K E+ +L L H +++K G C ++ E+ LV E+VP Sbjct 366 SGQEIAVKRLRKGSGQGGME-FKNEVLLLTRLQHRNLVKLLGFCNEKDEE--ILVYEFVP 422 Query 983 LGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDR 1035 SL ++ R + + + G+ YLH IHRDL A N+LLD + Sbjct 423 NSSLDHFIFDEEKRRVLTWDVRYTIIEGVARGLLYLHEDSQLRIIHRDLKASNILLDAEM 482 Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 K+ DFG+A+ + + APE +F SDV+SFGV L E++ Sbjct 483 NPKVADFGMARLFDMDETRGQTSR-VVGTYGYMAPEYATYGQFSTKSDVYSFGVMLLEMI 541 Query 1096 THCDSSQSPPTKFLELIGIA---QGQMTVLRLTELLERGERLP--RPDKCPCEVYHLMKN 1150 + + + + E + + R E+++ ++ H+ Sbjct 542 SGKSNKKLEKEEEEEEEELPAFVWKRWIEGRFAEIIDPLAAPSNNISINEVMKLIHIGLL 601 Query 1151 CWETEASFRPTFENLIPILKT 1171 C + + S RP+ +++ L+ Sbjct 602 CVQEDISKRPSINSILFWLER 622 Score = 236 bits (601), Expect = 7e-65, Method: Composition-based stats. Identities = 66/366 (18%), Positives = 119/366 (33%), Gaps = 67/366 (18%) Query 461 QAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSL----RLRKFPIEQQDGAFVL 516 Q + G + S R ++ R+ P + Sbjct 227 QKQFWGRQGGGVSRPSC----------YFRWDLYPYYRAFDNVVRVPAPPPQASSTIIDY 276 Query 517 EGWGRSF--PSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTL 574 +SF ++ + L+ FS +R ++ +I + +++ Sbjct 277 GRDEKSFQGSNIAIIVVPSVINLIIFVVLIFSWKR------KQSHTIINDVFDSNNGQSM 330 Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 L + + LGQG +VY+G L Sbjct 331 LRFDLRMIVTATNNFSLENKLGQGGFGSVYKGILPSGQ---------------------- 368 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 + +K L + F L++++ H +L + G C E I+V E+V + Sbjct 369 ---EIAVKRLRKGSGQGGMEFKNEVLLLTRLQHRNLVKLLGFCNEKDEEILVYEFVPNSS 425 Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAE 749 LD ++ E + W + + + +A L YL ++H ++ NILL Sbjct 426 LDHFIFDEEKRRVLTWDVRYTIIEGVARGLLYLHEDSQLRIIHRDLKASNILLD------ 479 Query 750 GTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 K++D G+ E R V ++APE G ST D + FG Sbjct 480 -AEMNPKVADFGMARLFDMDETRGQTSRVVGTYGYMAPEYATYG--QFSTKSDVYSFGVM 536 Query 804 LLEICF 809 LLE+ Sbjct 537 LLEMIS 542 >sp|P97793|ALK_MOUSE ALK tyrosine kinase receptor OS=Mus musculus OX=10090 GN=Alk PE=1 SV=2 Length=1621 Score = 258 bits (658), Expect = 8e-69, Method: Composition-based stats. Identities = 95/344 (28%), Positives = 142/344 (41%), Gaps = 34/344 (10%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 Q P ++ + + + S SD ++ + IR LG G FG+V Sbjct 1078 QSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEG 1137 Query 915 CYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 ND + VAVK L C Q + E I+ H++I++ G + Sbjct 1138 QVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRF 1197 Query 974 LQLVMEYVPLGSLRDYLPRH--------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 + L E + G L+ +L S+ + LL A+ I G YL H+IHRD+A Sbjct 1198 ILL--ELMAGGDLKSFLRETRPRPNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIA 1255 Query 1026 ARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082 ARN LL + KIGDFG+A+ + YYR PV W PE E F + Sbjct 1256 ARNCLLTCPGAGRIAKIGDFGMARDIYRA-SYYRKGGCAMLPVKWMPPEAFMEGIFTSKT 1314 Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 D WSFGV L+E+ + L + + + E + G R+ P CP Sbjct 1315 DTWSFGVLLWEIFS--------------LGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPG 1360 Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 VY +M CW+ + RP F ++ ++ Y Q P V + Sbjct 1361 PVYRIMTQCWQHQPEDRPNFAIILERIE-----YCTQDPDVINT 1399 Score = 254 bits (649), Expect = 1e-67, Method: Composition-based stats. Identities = 79/314 (25%), Positives = 123/314 (39%), Gaps = 40/314 (13%) Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 S V +K IT + LG G VYEG++ G +D PL Sbjct 1106 TSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQV---------SGMPNDPSPL------- 1149 Query 635 QELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +V +K L L F A ++S+ +H ++ GV ++ ++ E + G Sbjct 1150 ---QVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAGG 1206 Query 694 PLDVWLR--RERGHVPMAWKM----VVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 L +LR R R + P + M VA+ +A YLE + +H ++ RN LL Sbjct 1207 DLKSFLRETRPRPNQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLT---- 1262 Query 748 AEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFG 801 G K+ D G+ + + W+ PE G ++ D W FG Sbjct 1263 CPGAGRIAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGI--FTSKTDTWSFG 1320 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSF 859 L EI G P S+S E F R+ P +CP + + +QC ++P RP+F Sbjct 1321 VLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNF 1380 Query 860 RTILRDLTRLQPHN 873 IL + Sbjct 1381 AIILERIEYCTQDP 1394 >sp|C0LGU5|Y5457_ARATH Probable LRR receptor-like serine/threonine-protein kinase At5g45780 OS=Arabidopsis thaliana OX=3702 GN=At5g45780 PE=1 SV=1 Length=614 Score = 246 bits (629), Expect = 8e-69, Method: Composition-based stats. Identities = 80/328 (24%), Positives = 134/328 (41%), Gaps = 24/328 (7%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 + + + LG+G FG V G +VAV Sbjct 273 HVQQDYEFEIGHLKRFSFREIQTATSNFSPKNILGQGGFGMVYKGYL-----PNGTVVAV 327 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K LK D ++ E++++ H ++++ G C E+ LV Y+P GS+ D Sbjct 328 KRLK-DPIYTGEVQFQTEVEMIGLAVHRNLLRLFGFCMTPEER--MLVYPYMPNGSVADR 384 Query 990 LPRH-----SIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGD 1041 L + S+ + + A G+ YLH Q IHRD+ A N+LLD +GD Sbjct 385 LRDNYGEKPSLDWNRRISIALGAARGLVYLHEQCNPKIIHRDVKAANILLDESFEAIVGD 444 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLAK + + + V + APE L + +DV+ FGV + EL+T Sbjct 445 FGLAKLLDQRDSH--VTTAVRGTIGHIAPEYLSTGQSSEKTDVFGFGVLILELITGHKMI 502 Query 1102 QSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 + + ++ + R E+++R + D EV L C + + R Sbjct 503 DQGNGQVRKGMILSWVRTLKAEKRFAEMVDRDLKGEFDDLVLEEVVELALLCTQPHPNLR 562 Query 1160 PTFENLIPILKTVHEK----YQGQAPSV 1183 P ++ +L+ + E+ Y+ +APSV Sbjct 563 PRMSQVLKVLEGLVEQCEGGYEARAPSV 590 Score = 204 bits (519), Expect = 2e-54, Method: Composition-based stats. Identities = 67/352 (19%), Positives = 112/352 (32%), Gaps = 65/352 (18%) Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 +L + SF + + + LGQG VY+G L Sbjct 284 HLKRFSFREIQTATSNFSPKNILGQGGFGMVYKGYLPNG--------------------- 322 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 V +K L + + F ++ H +L + G C+ E ++V Y+ + Sbjct 323 ----TVVAVKRLKDPIYTGEVQFQTEVEMIGLAVHRNLLRLFGFCMTPEERMLVYPYMPN 378 Query 693 GPLDVWLRR---ERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLG 746 G + LR E+ + ++ +A A L YL + ++H +V NILL Sbjct 379 GSVADRLRDNYGEKPSLDWNRRISIALGAARGLVYLHEQCNPKIIHRDVKAANILLDESF 438 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFG 801 A + D G+ R+ V I +APE L G + S D +GFG Sbjct 439 EAI-------VGDFGLAKLLDQRDSHVTTAVRGTIGHIAPEYLSTGQS--SEKTDVFGFG 489 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP------------------EPSCPQLAT 843 +LE+ + Q K L + ++ Sbjct 490 VLILELITGHKMIDQGNGQVRKGMILSWVRTLKAEKRFAEMVDRDLKGEFDDLVLEEVVE 549 Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895 L C P RP +L+ L L P + ++ Sbjct 550 LALLCTQPHPNLRPRMSQVLKVLEGLVEQCEGGYEARAPSVSRNYSNGHEEQ 601 >sp|Q9CAC3|CRK43_ARATH Cysteine-rich receptor-like protein kinase 43 OS=Arabidopsis thaliana OX=3702 GN=CRK43 PE=2 SV=2 Length=413 Score = 240 bits (612), Expect = 9e-69, Method: Composition-based stats. Identities = 75/283 (27%), Positives = 111/283 (39%), Gaps = 18/283 (6%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 LGEG FG V G +AVK L Q ++ + E +L + H Sbjct 50 FHPTHKLGEGGFGPVFKGRL-----PDGRDIAVKKLSQ-VSRQGKNEFVNEAKLLAKVQH 103 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMA 1012 +++ G C +K LV EYV SL L + I Q I G+ Sbjct 104 RNVVNLWGYCTHGDDK--LLVYEYVVNESLDKVLFKSNRKSEIDWKQRFEIITGIARGLL 161 Query 1013 YLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH IHRD+ A N+LLD + KI DFG+A+ E + R G + A Sbjct 162 YLHEDAPNCIIHRDIKAGNILLDEKWVPKIADFGMARLYQEDVTHVNTRVAG--TNGYMA 219 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE + +DV+SFGV + EL++ +SS S L+ A R E+L Sbjct 220 PEYVMHGVLSVKADVFSFGVLVLELVSGQKNSSFSMRHPDQTLLEWAFKLYKKGRTMEIL 279 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 ++ + C + + RP+ + +L Sbjct 280 DQDIAASADPDQVKLCVQIGLLCVQGDPHQRPSMRRVSLLLSR 322 Score = 220 bits (561), Expect = 8e-62, Method: Composition-based stats. Identities = 72/357 (20%), Positives = 119/357 (33%), Gaps = 65/357 (18%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 K+ LG+G V++GRL GRD + +K L Sbjct 46 ATKDFHPTHKLGEGGFGPVFKGRL-------------------PDGRD------IAVKKL 80 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR--E 702 F A L+++V H ++ + G C G + ++V EYV + LD L + Sbjct 81 SQVSRQGKNEFVNEAKLLAKVQHRNVVNLWGYCTHGDDKLLVYEYVVNESLDKVLFKSNR 140 Query 703 RGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + + + + +A L YL ++H ++ NILL + K++D Sbjct 141 KSEIDWKQRFEIITGIARGLLYLHEDAPNCIIHRDIKAGNILLDEKWVP-------KIAD 193 Query 760 PGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ V ++APE + G LS D + FG +LE+ + Sbjct 194 FGMARLYQEDVTHVNTRVAGTNGYMAPEYVMHGV--LSVKADVFSFGVLVLELVSGQKNS 251 Query 815 LQSRSPSEKEHFYQ-----RQHRLPEPSCPQLA------------TLTSQCLTYEPTQRP 857 S ++ ++ R E +A + C+ +P QRP Sbjct 252 SFSMRHPDQTLLEWAFKLYKKGRTMEILDQDIAASADPDQVKLCVQIGLLCVQGDPHQRP 311 Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG----HFGK 910 S R + L+R H P S T G FG Sbjct 312 SMRRVSLLLSRKPGHLEEPDHPGVPGSRYRRRTQRPSGAASLGTLSTTGSSTDSFGS 368 >sp|P0CY46|EGFR_APIME Epidermal growth factor receptor OS=Apis mellifera OX=7460 GN=Egfr PE=2 SV=1 Length=1292 Score = 256 bits (655), Expect = 1e-68, Method: Composition-based stats. Identities = 96/274 (35%), Positives = 137/274 (50%), Gaps = 20/274 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + VA+K L G + E I+ ++ H ++++ Sbjct 717 LGYGAFGNVYKGVWVPEGENVKIPVAIKVLHDGTGANTSKEFLDEAYIMASVEHPNLLQL 776 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 C + LV + +PLG L D++ R IG LL + QI GMAYL + + Sbjct 777 LAVCMTS---QMMLVTQLMPLGCLLDFVRRFKDKIGSKALLNWCTQIARGMAYLEERRLV 833 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ VKI DFGLAK + E Y+ G P+ W A EC++ F + Sbjct 834 HRDLAARNVLVQTPNCVKITDFGLAKLLDINEEQYKA-AGGKMPIKWLALECIQHRVFTH 892 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVW+FGVT++E+LT+ G + + ELLE+GERLP+P C Sbjct 893 KSDVWAFGVTIWEVLTYG--------------GRPYENVPARNVPELLEKGERLPQPAIC 938 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 +VY +M CW +A RP+F+ L + Sbjct 939 TIDVYMIMIKCWMLDAESRPSFKELAEDFAKMSR 972 Score = 233 bits (593), Expect = 5e-61, Method: Composition-based stats. Identities = 86/440 (20%), Positives = 164/440 (37%), Gaps = 60/440 (14%) Query 475 WSTSHPYRLILTVAQRSQAPDGMQSLRLRKF-PIEQQDGAFVLEG---WGRSFPSVRELG 530 + +P+++ PD L IE + +L G + +F V + Sbjct 610 CTPEYPHKIF--------NPDSEPYCSLETAGLIENELQPAILAGVAVFALAFLVVAAII 661 Query 531 AALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEIT 590 +A ++ + + L R + NL++L + ++E+ Sbjct 662 MYFWRVRAKAKENTVKMTMAL-------TGLDDNEPLRPTGVKPNLAKLRI--IKEEEMR 712 Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHH 649 + LG G NVY+G EG ++ V +KVL D + Sbjct 713 KGGILGYGAFGNVYKGVWVPEGENV--------------------KIPVAIKVLHDGTGA 752 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 + + F + A +M+ V H +L + VC+ + ++VT+ + G L ++RR + + Sbjct 753 NTSKEFLDEAYIMASVEHPNLLQLLAVCMTS-QMMLVTQLMPLGCLLDFVRRFKDKIGSK 811 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 + Q+A ++YLE + LVH ++ RN+L+ T +K++D G+ Sbjct 812 ALLNWCTQIARGMAYLEERRLVHRDLAARNVLV-------QTPNCVKITDFGLAKLLDIN 864 Query 770 EERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 EE+ + I WLA EC+ + D W FG T+ E+ G P ++ Sbjct 865 EEQYKAAGGKMPIKWLALECIQHRV--FTHKSDVWAFGVTIWEVLTYGGRPYENVPARNV 922 Query 824 EHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 ++ RLP+P + + +C + RPSF+ + D ++ + Sbjct 923 PELLEKGERLPQPAICTIDVYMIMIKCWMLDAESRPSFKELAEDFAKMSRDPGRYLAIKG 982 Query 882 PDSPASDPTVFHKRYLKKIR 901 Sbjct 983 DKYMRLPSYTLQDEKEMIRN 1002 >sp|Q54L00|LIMKA_DICDI Probable LIM domain-containing serine/threonine-protein kinase DDB_G0287001 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0287001 PE=3 SV=1 Length=650 Score = 247 bits (630), Expect = 1e-68, Method: Composition-based stats. Identities = 71/276 (26%), Positives = 116/276 (42%), Gaps = 30/276 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY--HEHII 960 + G GKV Y + VA+K ++ + + +E+ I+ + H + Sbjct 392 IASGASGKVYKGIYKGRD------VAIKVYSSENFCFNIEEFDREVTIMSLIDSDHPNFT 445 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ G Q +K L V E V GSLRD L + L A I M +LH+ Sbjct 446 RFYGA-NKQNKKYLFHVSELVKSGSLRDLLLDKEKPLAYFTQLSIASDIANAMKHLHSIG 504 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRDL + NVL+ D K+ DFG ++ V + + + +PE K + Sbjct 505 VIHRDLKSLNVLITEDFTAKVIDFGTSRNV----DLAKQMTLNLGTSCYMSPELFKGNGY 560 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 DV++FG+ L+E++ + + + L+ +GER P Sbjct 561 DETCDVYAFGIVLWEIIARKEP---------------YENINSWSIPVLVAKGERPTIPA 605 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 CP E L+K CW + RP+F+ + LK + E Sbjct 606 DCPSEYSKLIKACWTDKPKKRPSFKEICDTLKKISE 641 Score = 182 bits (462), Expect = 1e-46, Method: Composition-based stats. Identities = 56/298 (19%), Positives = 111/298 (37%), Gaps = 45/298 (15%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 + + ++E+ + G VY+G + GRD V Sbjct 378 YKELSKEEVAFGDVIASGASGKVYKG--------------------IYKGRD------VA 411 Query 641 LKVLDPSHHDI-ALAFYETASLMSQVS--HTHLAFVHGVCVRGPENIM-VTEYVEHGPLD 696 +KV + F ++MS + H + +G + + + V+E V+ G L Sbjct 412 IKVYSSENFCFNIEEFDREVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSELVKSGSLR 471 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 L + + ++ +A +A+A+ +L + ++H ++ N+L+ K Sbjct 472 DLLLDKEKPLAYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITE-------DFTAK 524 Query 757 LSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 + D G ++ +++PE G N D + FG L EI E Sbjct 525 VIDFGTSRNVDLAKQMTLNLGTSCYMSPELFKG--NGYDETCDVYAFGIVLWEIIARKE- 581 Query 814 PLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 P ++ + + R +P + + L C T +P +RPSF+ I L ++ Sbjct 582 PYENINSWSIPVLVAKGERPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICDTLKKI 639 >sp|Q9ZT07|RKS1_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase RKS1 OS=Arabidopsis thaliana OX=3702 GN=RKS1 PE=3 SV=3 Length=833 Score = 251 bits (641), Expect = 1e-68, Method: Composition-based stats. Identities = 81/345 (23%), Positives = 140/345 (41%), Gaps = 25/345 (7%) Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFH------ 893 L T+ C+ E + R+ + + + + +F Sbjct 451 MLLTVILFCVVRERRKSNRHRSSSANFAPVPFDFDESFRFEQDKARNRELPLFDLNTIVA 510 Query 894 -KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 LG G FG V +AVK L + G Q +K E+ ++ Sbjct 511 ATNNFSSQNKLGAGGFGPVYKGVLQNR-----MEIAVKRLSRNSG-QGMEEFKNEVKLIS 564 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQIC 1008 L H ++++ GCC + EK LV EY+P SL ++ R + + + + I Sbjct 565 KLQHRNLVRILGCCVELEEK--MLVYEYLPNKSLDYFIFHEEQRAELDWPKRMEIVRGIA 622 Query 1009 EGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 G+ YLH IHRDL A N+LLD++ + KI DFG+A+ G++ Sbjct 623 RGILYLHQDSRLRIIHRDLKASNILLDSEMIPKISDFGMARIFG-GNQMEGCTSRVVGTF 681 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 + APE E +F SDV+SFGV + E++T +S + L+G T Sbjct 682 GYMAPEYAMEGQFSIKSDVYSFGVLMLEIITGKKNSAF-HEESSNLVGHIWDLWENGEAT 740 Query 1126 ELLERG-ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 E+++ ++ ++ + + C + AS R +++ +L Sbjct 741 EIIDNLMDQETYDEREVMKCIQIGLLCVQENASDRVDMSSVVIML 785 Score = 236 bits (603), Expect = 9e-64, Method: Composition-based stats. Identities = 65/383 (17%), Positives = 117/383 (31%), Gaps = 61/383 (16%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 P P + +A R L L L+ + + LG G VY+G L+ Sbjct 479 PVPFDFDESFRFEQDKARNRELPLFDLNTIVAATNNFSSQNKLGAGGFGPVYKGVLQNR- 537 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAF 672 + + +K L + F L+S++ H +L Sbjct 538 ------------------------MEIAVKRLSRNSGQGMEEFKNEVKLISKLQHRNLVR 573 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK-- 728 + G CV E ++V EY+ + LD ++ E + W +M + + +A + YL Sbjct 574 ILGCCVELEEKMLVYEYLPNKSLDYFIFHEEQRAELDWPKRMEIVRGIARGILYLHQDSR 633 Query 729 -NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWLAP 781 ++H ++ NILL + K+SD G+ V ++AP Sbjct 634 LRIIHRDLKASNILLDSEMIP-------KISDFGMARIFGGNQMEGCTSRVVGTFGYMAP 686 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS----------------EKEH 825 E G S D + FG +LEI + S E Sbjct 687 EYAMEG--QFSIKSDVYSFGVLMLEIITGKKNSAFHEESSNLVGHIWDLWENGEATEIID 744 Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885 Q E + + C+ + R +++ L + + Sbjct 745 NLMDQETYDEREVMKCIQIGLLCVQENASDRVDMSSVVIMLGHNATNLPNPKHPAFTSAR 804 Query 886 ASDPTVFHKRYLKKIRDLGEGHF 908 + + + F Sbjct 805 RRGGENGACLKGQTGISVNDVTF 827 >sp|P15208|INSR_MOUSE Insulin receptor OS=Mus musculus OX=10090 GN=Insr PE=1 SV=2 Length=1372 Score = 256 bits (655), Expect = 1e-68, Method: Composition-based stats. Identities = 90/304 (30%), Positives = 146/304 (48%), Gaps = 29/304 (10%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGP 938 D + + +R+LG+G FG V G E VAVK + Sbjct 996 FPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASL 1055 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------- 991 + R + E +++ H+++ G +G+ +L +VME + G L+ +L Sbjct 1056 RERIEFLNEASVMKGFTCHHVVRLLGVV-SKGQPTL-VVMELMAHGDLKSHLRSLRPDAE 1113 Query 992 ----RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 R L +++ +I +GMAYL+A+ ++HRDLAARN ++ +D VKIGDFG+ + Sbjct 1114 NNPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRD 1173 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + E +YYR G PV W +PE LK+ F +SD+WSFGV L+E+ + Sbjct 1174 IYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITS----------- 1221 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L ++ ++ + + G L PD CP + LM+ CW+ RPTF ++ Sbjct 1222 ---LAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVN 1278 Query 1168 ILKT 1171 +LK Sbjct 1279 LLKD 1282 Score = 249 bits (636), Expect = 3e-66, Method: Composition-based stats. Identities = 97/519 (19%), Positives = 179/519 (34%), Gaps = 82/519 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPF----VQAKLRPED----GLYLIHW-STSHPYRLILTVA 488 V+ + + D I GP+ V + E GL +++ S L + Sbjct 830 VSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLC 889 Query 489 QRSQAPDGMQSLRLRKFPIEQ-----------------QDGAFVLEGWGRSFPSVREL-- 529 + + RLR + F + + ++ ++ Sbjct 890 VSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIII 949 Query 530 --GAALQGCLLRAGDDCFSLRRCCLPQPGE----TSNLIIMRGARASPRTLNLSQLSFHR 583 + + G LR+ P +SN + + P ++ + Sbjct 950 GPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVP--DEWE 1007 Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +++IT L LGQG+ VYEG + G+ E RV +K Sbjct 1008 VPREKITLLRELGQGSFGMVYEGNAKDIIKGEA-------------------ETRVAVKT 1048 Query 644 LDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR- 701 ++ S + F AS+M + H+ + GV +G ++V E + HG L LR Sbjct 1049 VNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSL 1108 Query 702 --------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 R + + + ++A ++YL K VH ++ RN ++A Sbjct 1109 RPDAENNPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAH-------DF 1161 Query 754 FIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+ D G+ + + + W++PE L G + + D W FG L EI Sbjct 1162 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTASSDMWSFGVVLWEI 1219 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 E P Q S + F L P+ +L L C + P RP+F I+ Sbjct 1220 TSLAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNL 1279 Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 L + +V + + + + + + ++ Sbjct 1280 LKDDLHPSFPEVSFFYSEENKAPESEELEMEFEDMENVP 1318 >sp|Q9XEC8|CRK38_ARATH Cysteine-rich receptor-like protein kinase 38 OS=Arabidopsis thaliana OX=3702 GN=CRK38 PE=3 SV=1 Length=648 Score = 247 bits (630), Expect = 1e-68, Method: Composition-based stats. Identities = 76/303 (25%), Positives = 118/303 (39%), Gaps = 19/303 (6%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933 D + + +G+G FG V GE +AVK L Sbjct 316 QYDYGGQSKLRFDFRMILTATDDFSFENKIGQGGFGSVYKGKLPG-----GEEIAVKRLT 370 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--- 990 G Q ++ E+ +L L H +++K G C + E+ LV E+VP SL ++ Sbjct 371 RGSG-QGEIEFRNEVLLLTRLQHRNLVKLLGFCNEGDEE--ILVYEFVPNSSLDHFIFDE 427 Query 991 -PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 R + + + G+ YLH IHRDL A N+LLD K+ DFG+A+ Sbjct 428 EKRLLLTWDMRARIIEGVARGLVYLHEDSQLRIIHRDLKASNILLDAYMNPKVADFGMAR 487 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 R+ + APE ++ F +DV+SFGV L E++T S Sbjct 488 LFNMDQTRAVTRK-VVGTFGYMAPEYVRNRTFSVKTDVYSFGVVLLEMITGR--SNKNYF 544 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + L L A +++ R ++ H+ C + S RPT +I Sbjct 545 EALGLPAYAWKCWVAGEAASIIDHVLSRSRSNEI-MRFIHIGLLCVQENVSKRPTMSLVI 603 Query 1167 PIL 1169 L Sbjct 604 QWL 606 Score = 233 bits (595), Expect = 5e-64, Method: Composition-based stats. Identities = 49/244 (20%), Positives = 90/244 (37%), Gaps = 45/244 (18%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 + + + +GQG +VY+G+L Sbjct 327 FDFRMILTATDDFSFENKIGQGGFGSVYKGKLPGGE------------------------ 362 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 + +K L + F L++++ H +L + G C G E I+V E+V + LD Sbjct 363 -EIAVKRLTRGSGQGEIEFRNEVLLLTRLQHRNLVKLLGFCNEGDEEILVYEFVPNSSLD 421 Query 697 VWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGT 751 ++ E + + W + + + +A L YL ++H ++ NILL Sbjct 422 HFIFDEEKRLLLTWDMRARIIEGVARGLVYLHEDSQLRIIHRDLKASNILLD-------A 474 Query 752 SPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 K++D G+ + R V ++APE + + S D + FG LL Sbjct 475 YMNPKVADFGMARLFNMDQTRAVTRKVVGTFGYMAPEYVRN--RTFSVKTDVYSFGVVLL 532 Query 806 EICF 809 E+ Sbjct 533 EMIT 536 >sp|Q9SXB8|Y1133_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g11330 OS=Arabidopsis thaliana OX=3702 GN=At1g11330 PE=1 SV=3 Length=842 Score = 251 bits (641), Expect = 1e-68, Method: Composition-based stats. Identities = 81/280 (29%), Positives = 116/280 (41%), Gaps = 17/280 (6%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG V G+ +AVK L G Q E+ ++ L H ++ Sbjct 527 RNKLGQGGFGPVYKG-----KLPEGQEIAVKRLSRKSG-QGLEELMNEVVVISKLQHRNL 580 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015 +K GCC + E+ LV EY+P SL YL + + + IC G+ YLH Sbjct 581 VKLLGCCIEGEER--MLVYEYMPKKSLDAYLFDPMKQKILDWKTRFNIMEGICRGLLYLH 638 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 IHRDL A N+LLD + KI DFGLA+ + R + +PE Sbjct 639 RDSRLKIIHRDLKASNILLDENLNPKISDFGLARIFRANEDEANTRR-VVGTYGYMSPEY 697 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 E F SDV+S GV E+++ SS L L+ A L + Sbjct 698 AMEGFFSEKSDVFSLGVIFLEIISGRRNSSSHKEENNLNLLAYAWKLWNDGEAASLADPA 757 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +K + H+ C + A+ RP N+I +L T Sbjct 758 VFDKCFEKEIEKCVHIGLLCVQEVANDRPNVSNVIWMLTT 797 Score = 235 bits (599), Expect = 4e-63, Method: Composition-based stats. Identities = 58/341 (17%), Positives = 108/341 (32%), Gaps = 62/341 (18%) Query 521 RSFPSVRELGAALQGCLLRAGDDCFSL------RRCCLPQPGETSNLIIMRGARASPRTL 574 ++ ++ + AA ++ C L +R + + A S Sbjct 440 KTHSNLAVMIAAPVIGVMLIAAVCVLLACRKYKKRPAPAKDRSAELMFKRMEALTSDNES 499 Query 575 NLSQLSFHRVD----------QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 +Q+ + + + LGQG VY+G+L Sbjct 500 ASNQIKLKELPLFEFQVLATSTDSFSLRNKLGQGGFGPVYKGKLPEGQ------------ 547 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 + +K L ++S++ H +L + G C+ G E + Sbjct 548 -------------EIAVKRLSRKSGQGLEELMNEVVVISKLQHRNLVKLLGCCIEGEERM 594 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRN 739 +V EY+ LD +L + W + + + + L YL ++H ++ N Sbjct 595 LVYEYMPKKSLDAYLFDPMKQKILDWKTRFNIMEGICRGLLYLHRDSRLKIIHRDLKASN 654 Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLST 793 ILL + K+SD G+ + E+ V +++PE G S Sbjct 655 ILLDE-------NLNPKISDFGLARIFRANEDEANTRRVVGTYGYMSPEYAMEGF--FSE 705 Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834 D + G LEI G S + +L Sbjct 706 KSDVFSLGVIFLEIIS-GRRNSSSHKEENNLNLLAYAWKLW 745 >sp|Q9M9E0|LRKS1_ARATH L-type lectin-domain containing receptor kinase S.1 OS=Arabidopsis thaliana OX=3702 GN=LECRKS1 PE=1 SV=1 Length=656 Score = 247 bits (630), Expect = 1e-68, Method: Composition-based stats. Identities = 91/432 (21%), Positives = 156/432 (36%), Gaps = 24/432 (6%) Query 749 EGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG--ATLLE 806 +G + I +S VG+ R R P +A S + W Sbjct 212 DGPNFQINVSVAPVGVLRPRRPTLTFRDPVIANYVSADMYAGFSASKTNWNEARRILAWS 271 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR-- 864 + G + + L +A + C+ + I + Sbjct 272 LSDTGALREINTTNLPVFFLENSSSSLSTG---AIAGIVIGCVVFVALIGFGGYLIWKKL 328 Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 + L P + + R LG G FGKV Sbjct 329 MREEEEEEIEEWELEFWPHRFSYEELAAATEVFSNDRLLGSGGFGKVYRGIL-----SNN 383 Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 +AVK + D Q + EI + L H+++++ +G C + E L LV +Y+P G Sbjct 384 SEIAVKCVNHD-SKQGLREFMAEISSMGRLQHKNLVQMRGWCRRKNE--LMLVYDYMPNG 440 Query 985 SLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVK 1038 SL ++ P+ + + + EG+ YLH Q IHRD+ + N+LLD++ + Sbjct 441 SLNQWIFDNPKEPMPWRRRRQVINDVAEGLNYLHHGWDQVVIHRDIKSSNILLDSEMRGR 500 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 +GDFGLAK G R + + APE ASDV+SFGV + E+++ Sbjct 501 LGDFGLAKLYEHGGAPNTTR--VVGTLGYLAPELASASAPTEASDVYSFGVVVLEVVSGR 558 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE-VYHLMKNCWETEAS 1157 + + + L+ + R+ + + R E + L C + + Sbjct 559 RPIEYAEEEDMVLVDWVRDLYGGGRVVDAADERVRSECETMEEVELLLKLGLACCHPDPA 618 Query 1158 FRPTFENLIPIL 1169 RP ++ +L Sbjct 619 KRPNMREIVSLL 630 Score = 214 bits (545), Expect = 3e-57, Method: Composition-based stats. Identities = 60/304 (20%), Positives = 106/304 (35%), Gaps = 60/304 (20%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + + LG G VY G L + +K + Sbjct 357 ATEVFSNDRLLGSGGFGKVYRGILSNNS-------------------------EIAVKCV 391 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-R 703 + F S M ++ H +L + G C R E ++V +Y+ +G L+ W+ + Sbjct 392 NHDSKQGLREFMAEISSMGRLQHKNLVQMRGWCRRKNELMLVYDYMPNGSLNQWIFDNPK 451 Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 +P + V +A L+YL ++ ++H ++ NILL +L D Sbjct 452 EPMPWRRRRQVINDVAEGLNYLHHGWDQVVIHRDIKSSNILLDSEMRG-------RLGDF 504 Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ GA + V + +LAPE A + A D + FG +LE+ Sbjct 505 GLAKLYEHGGAPNTTRVVGTLGYLAPELASASAP--TEASDVYSFGVVVLEVVSGRRPIE 562 Query 816 QSRSPSEKEHFYQR----QHRLPEPSCPQ-------------LATLTSQCLTYEPTQRPS 858 + + R R+ + + + L L C +P +RP+ Sbjct 563 YAEEEDMVLVDWVRDLYGGGRVVDAADERVRSECETMEEVELLLKLGLACCHPDPAKRPN 622 Query 859 FRTI 862 R I Sbjct 623 MREI 626 >sp|Q9PVZ4|INSR_XENLA Insulin receptor OS=Xenopus laevis OX=8355 GN=insr PE=1 SV=1 Length=1362 Score = 256 bits (655), Expect = 1e-68, Method: Composition-based stats. Identities = 92/313 (29%), Positives = 151/313 (48%), Gaps = 29/313 (9%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAV 929 + + D + + +R+LG+G FG V G E+ VAV Sbjct 986 YTSSNPEYLSASEVYIPDEWEVPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPEVRVAV 1045 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K + + R + E +++ H+++ G +G+ +L ++ME + G L+ Y Sbjct 1046 KTVNESASLRERIEFLNEASVMKAFNCHHVVRLLGVV-SKGQPTL-VIMELMAHGDLKSY 1103 Query 990 LP-----------RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 L R + L +++ A +I +GMAYL+A+ ++HRDLAARN ++ +D VK Sbjct 1104 LRSLRPDAENNPGRLAPTLKEIIQMAAEISDGMAYLNAKKFVHRDLAARNCMVADDYAVK 1163 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 IGDFG+ + + E +YYR G PV W +PE LK+ F SDVWSFGV L+E+ + Sbjct 1164 IGDFGMTRDIYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTAFSDVWSFGVVLWEITS-- 1220 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 L ++ ++ + + G L P+ CP ++ LM+ CW+ Sbjct 1221 ------------LAEQPYQGLSNEQVLKFVMDGGSLDHPENCPPRLHSLMQMCWQYNPKM 1268 Query 1159 RPTFENLIPILKT 1171 RPTF +I +LK Sbjct 1269 RPTFLEIIDMLKD 1281 Score = 254 bits (648), Expect = 1e-67, Method: Composition-based stats. Identities = 86/398 (22%), Positives = 148/398 (37%), Gaps = 49/398 (12%) Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQL---SFHRV 584 + + G ++ L C + + + ++P L+ S++ V Sbjct 948 NIVKIITGPIIAVFLLLIVLVYCVVQKKKDAEGPAGPLYTSSNPEYLSASEVYIPDEWEV 1007 Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + +I L LGQG+ VYEG + G+P E+RV +K + Sbjct 1008 PRDKINLLRELGQGSFGMVYEGIAKDIIKGEP-------------------EVRVAVKTV 1048 Query 645 DPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + S + F AS+M + H+ + GV +G +++ E + HG L +LR R Sbjct 1049 NESASLRERIEFLNEASVMKAFNCHHVVRLLGVVSKGQPTLVIMELMAHGDLKSYLRSLR 1108 Query 704 GH---------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 + + +A +++ ++YL K VH ++ RN ++A Sbjct 1109 PDAENNPGRLAPTLKEIIQMAAEISDGMAYLNAKKFVHRDLAARNCMVA-------DDYA 1161 Query 755 IKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 +K+ D G+ + + + W++PE L G + D W FG L EI Sbjct 1162 VKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTAFSDVWSFGVVLWEIT 1219 Query 809 FDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 E P Q S + F L PE P+L +L C Y P RP+F I+ L Sbjct 1220 SLAEQPYQGLSNEQVLKFVMDGGSLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDML 1279 Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 + DV D T + + + Sbjct 1280 KDDLRPSFQDVSFYYSDENKPPETDDLEIDFENMESTP 1317 >sp|Q9FPR3|EDR1_ARATH Serine/threonine-protein kinase EDR1 OS=Arabidopsis thaliana OX=3702 GN=EDR1 PE=1 SV=1 Length=933 Score = 253 bits (645), Expect = 1e-68, Method: Composition-based stats. Identities = 77/278 (28%), Positives = 124/278 (45%), Gaps = 30/278 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G +G+V + G VAVK L D + ++ E+ I+R L H +++ Sbjct 674 RIGLGSYGEVYHADWH------GTEVAVKKFLDQDFSGAALAEFRSEVRIMRRLRHPNVV 727 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH 1018 + G +L +V E++P GSL L R I + + A + GM LH Sbjct 728 FFLGAVTRP--PNLSIVTEFLPRGSLYRILHRPKSHIDERRRIKMALDVAMGMNCLHTST 785 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL N+L+DN+ VK+GDFGL++ H + + W APE L+ Sbjct 786 PTIVHRDLKTPNLLVDNNWNVKVGDFGLSRL---KHNTFLSSKSTAGTPEWMAPEVLRNE 842 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 DV+SFGV L+EL T + G + + + + RL Sbjct 843 PSNEKCDVYSFGVILWELATLRLPWR--------------GMNPMQVVGAVGFQNRRLEI 888 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 P + V ++ CW+T+ + RP+F L +LK ++ Sbjct 889 PKELDPVVGRIILECWQTDPNLRPSFAQLTEVLKPLNR 926 Score = 238 bits (607), Expect = 9e-64, Method: Composition-based stats. Identities = 64/313 (20%), Positives = 116/313 (37%), Gaps = 45/313 (14%) Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 R P+ L+ + + + ++ +G G+ VY Sbjct 648 RNDPQVLDDADVGECEIPWNDLVIAERIGLGSYGEVYHADW------------------- 688 Query 628 VPGRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 G E+ V K LD F +M ++ H ++ F G R P +V Sbjct 689 -----HGTEVAVK-KFLDQDFSGAALAEFRSEVRIMRRLRHPNVVFFLGAVTRPPNLSIV 742 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK--NLVHGNVCGRNILLAR 744 TE++ G L L R + H+ ++ +A +A ++ L +VH ++ N+L+ Sbjct 743 TEFLPRGSLYRILHRPKSHIDERRRIKMALDVAMGMNCLHTSTPTIVHRDLKTPNLLVDN 802 Query 745 LGLAEGTSPFIKLSDPGVGLGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800 + +K+ D G+ LS + W+APE L + + D + F Sbjct 803 -------NWNVKVGDFGLSRLKHNTFLSSKSTAGTPEWMAPEVLRNEPS--NEKCDVYSF 853 Query 801 GATLLEICFDGEAPLQSRSPSEK---EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857 G L E+ P + +P + F R+ +P+ P + + +C +P RP Sbjct 854 GVILWELATL-RLPWRGMNPMQVVGAVGFQNRRLEIPKELDPVVGRIILECWQTDPNLRP 912 Query 858 SFRTILRDLTRLQ 870 SF + L L Sbjct 913 SFAQLTEVLKPLN 925 >sp|Q25197|HTK7_HYDVU Putative insulin-like peptide receptor OS=Hydra vulgaris OX=6087 GN=HTK7 PE=2 SV=1 Length=1477 Score = 257 bits (656), Expect = 1e-68, Method: Composition-based stats. Identities = 89/320 (28%), Positives = 141/320 (44%), Gaps = 24/320 (8%) Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918 R + +D+ + ++ + + D ++ ++ IR+LG+G FG V Sbjct 1006 HRKLEKDVQGVLYASVNPEYMNSKEVYIPDEWELNREKIELIRELGQGSFGMVFEGIAHG 1065 Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978 D VAVK + R QE I++ H++K G +VM Sbjct 1066 IGDHAELRVAVKTTNENASIHDRIQILQEASIMKAFNCNHVVKLIGVVSQGQPT--FVVM 1123 Query 979 EYVPLGSLRDYLPRH-------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031 E + G L+ YL + ++ +I +GMAYL A+ ++H DLAARN ++ Sbjct 1124 ELMGRGDLKSYLKERRPDDGGIPLMRQEIYQMVAEIADGMAYLAARKFVHCDLAARNCMV 1183 Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091 +D VKIGDFG+A+ + E YYR P+ W APE LK+ F ASDVWSFGV L Sbjct 1184 ASDFTVKIGDFGMARDIYE-RNYYRKDGKSLLPIRWMAPESLKDGIFSTASDVWSFGVVL 1242 Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 +E+ T L T ++ + L P+ C ++ M C Sbjct 1243 WEICT--------------LASQPYQGKTNEQVLNFVLSNGHLDYPEGCDYQLREFMSLC 1288 Query 1152 WETEASFRPTFENLIPILKT 1171 W + RP+F ++ +L+ Sbjct 1289 WHRDPKMRPSFLEIVHVLEN 1308 Score = 241 bits (614), Expect = 2e-63, Method: Composition-based stats. Identities = 94/446 (21%), Positives = 166/446 (37%), Gaps = 58/446 (13%) Query 470 LYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVREL 529 Y+I S + + S A +G + + F + + L + + + Sbjct 934 TYIIRKS--RFGNYVAKIRAISPAGNGSWTEEI-HFKVAE------LSVTKNNNQLIIGI 984 Query 530 GAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQL---SFHRVDQ 586 +A+ + F L L + E ++ A +P +N ++ +++ Sbjct 985 ISAVS--AVIVALLVFILLYMFLHRKLEKDVQGVL-YASVNPEYMNSKEVYIPDEWELNR 1041 Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 ++I + LGQG+ V+EG + G ELRV +K + Sbjct 1042 EKIELIRELGQGSFGMVFEG--------------------IAHGIGDHAELRVAVKTTNE 1081 Query 647 SHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-- 703 + + AS+M + H+ + GV +G +V E + G L +L+ R Sbjct 1082 NASIHDRIQILQEASIMKAFNCNHVVKLIGVVSQGQPTFVVMELMGRGDLKSYLKERRPD 1141 Query 704 -GHVPM--AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G +P+ + ++A ++YL + VH ++ RN ++A + +K+ D Sbjct 1142 DGGIPLMRQEIYQMVAEIADGMAYLAARKFVHCDLAARNCMVA-------SDFTVKIGDF 1194 Query 761 GVGLGALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ R + I W+APE L G STA D W FG L EIC P Sbjct 1195 GMARDIYERNYYRKDGKSLLPIRWMAPESLKDGI--FSTASDVWSFGVVLWEICTLASQP 1252 Query 815 LQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 Q ++ + +F L PE QL S C +P RPSF I+ L Sbjct 1253 YQGKTNEQVLNFVLSNGHLDYPEGCDYQLREFMSLCWHRDPKMRPSFLEIVHVLENEVDD 1312 Query 873 NLADVLTVNPDSPASDPTVFHKRYLK 898 + V + + ++ K Sbjct 1313 DFVMVSFYHEMKRKALEDIYMKSESY 1338 >sp|P0DV84|ALK_CANLF ALK tyrosine kinase receptor OS=Canis lupus familiaris OX=9615 GN=ALK PE=3 SV=1 Length=1631 Score = 257 bits (656), Expect = 1e-68, Method: Composition-based stats. Identities = 95/344 (28%), Positives = 142/344 (41%), Gaps = 34/344 (10%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 Q P ++ + + + S SD ++ + IR LG G FG+V Sbjct 1089 QSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEG 1148 Query 915 CYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 +D + VAVK L C Q + E I+ H++I++ G + Sbjct 1149 QVSGVPSDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRF 1208 Query 974 LQLVMEYVPLGSLRDYLPR--------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 + L E + G L+ +L S+ + LL AQ I G YL H+IHRD+A Sbjct 1209 ILL--ELMAGGDLKSFLRETRPRPNQPSSLAMLDLLHVAQDIACGCQYLEENHFIHRDIA 1266 Query 1026 ARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082 ARN LL + KIGDFG+A+ + YYR PV W PE E F + Sbjct 1267 ARNCLLTCPGPGRVAKIGDFGMARDIYRA-SYYRKGGCAMLPVKWMPPEAFMEGIFTSKT 1325 Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 D WSFGV L+E+ + L + + + E + G R+ P CP Sbjct 1326 DTWSFGVLLWEIFS--------------LGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPG 1371 Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 VY +M CW+ + RP F ++ ++ Y Q P V + Sbjct 1372 PVYRIMTQCWQHQPEDRPNFAIILERIE-----YCTQDPDVINT 1410 Score = 253 bits (647), Expect = 2e-67, Method: Composition-based stats. Identities = 80/343 (23%), Positives = 126/343 (37%), Gaps = 40/343 (12%) Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 S V +K IT + LG G VYEG++ G D PL Sbjct 1117 TSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQV---------SGVPSDPSPL------- 1160 Query 635 QELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +V +K L L F A ++S+ +H ++ GV ++ ++ E + G Sbjct 1161 ---QVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAGG 1217 Query 694 PLDVWLR--RERGHVPMAWKM----VVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 L +LR R R + P + M VAQ +A YLE + +H ++ RN LL Sbjct 1218 DLKSFLRETRPRPNQPSSLAMLDLLHVAQDIACGCQYLEENHFIHRDIAARNCLLT---- 1273 Query 748 AEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFG 801 G K+ D G+ + + W+ PE G ++ D W FG Sbjct 1274 CPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGI--FTSKTDTWSFG 1331 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSF 859 L EI G P S+S E F R+ P +CP + + +QC ++P RP+F Sbjct 1332 VLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNF 1391 Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902 IL + + + + + Sbjct 1392 AIILERIEYCTQDPDVINTALPVEYGPLMEEEEKVPMRPQDPE 1434 >sp|O64776|Y1144_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61440 OS=Arabidopsis thaliana OX=3702 GN=At1g61440 PE=3 SV=2 Length=792 Score = 250 bits (638), Expect = 2e-68, Method: Composition-based stats. Identities = 74/307 (24%), Positives = 119/307 (39%), Gaps = 17/307 (6%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 + LG G FG V G +AVK L + Q + Sbjct 465 FFEMNTIQTATSNFSLSNKLGHGGFGSVYKGKLQ-----DGREIAVKRLSS-SSEQGKQE 518 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ 999 + EI ++ L H ++++ GCC + EK L+ E++ SL ++ R + + Sbjct 519 FMNEIVLISKLQHRNLVRVLGCCVEGKEK--LLIYEFMKNKSLDTFVFGSRKRLELDWPK 576 Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 Q I G+ YLH IHRDL N+LLD KI DFGLA+ +G +Y Sbjct 577 RFDIIQGIVRGLLYLHRDSRLRVIHRDLKVSNILLDEKMNPKISDFGLARLF-QGSQYQD 635 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIA 1115 + + +PE F SD++SFGV L E+++ S S + L+ Sbjct 636 KTRRVVGTLGYMSPEYAWTGVFSEKSDIYSFGVLLLEIISGEKISRFSYGEEGKALLAYV 695 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 R LL++ + C + + + RP L+ +L T + Sbjct 696 WECWCETRGVNLLDQALDDSSHPAEVGRCVQIGLLCVQHQPADRPNTLELLSMLTTTSDL 755 Query 1176 YQGQAPS 1182 + P+ Sbjct 756 PLPKQPT 762 Score = 232 bits (591), Expect = 2e-62, Method: Composition-based stats. Identities = 53/247 (21%), Positives = 95/247 (38%), Gaps = 45/247 (18%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L +++ + + + LG G +VY+G+L+ Sbjct 463 LEFFEMNTIQTATSNFSLSNKLGHGGFGSVYKGKLQDGR--------------------- 501 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + +K L S F L+S++ H +L V G CV G E +++ E++++ Sbjct 502 ----EIAVKRLSSSSEQGKQEFMNEIVLISKLQHRNLVRVLGCCVEGKEKLLIYEFMKNK 557 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748 LD ++ R + + W + + Q + L YL ++H ++ NILL Sbjct 558 SLDTFVFGSRKRLELDWPKRFDIIQGIVRGLLYLHRDSRLRVIHRDLKVSNILLDEK--- 614 Query 749 EGTSPFIKLSDPGVGL----GALSREER--VERIPWLAPECLPGGANSLSTAMDKWGFGA 802 K+SD G+ + R V + +++PE G S D + FG Sbjct 615 ----MNPKISDFGLARLFQGSQYQDKTRRVVGTLGYMSPEYAWTGV--FSEKSDIYSFGV 668 Query 803 TLLEICF 809 LLEI Sbjct 669 LLLEIIS 675 >sp|A0JM20|TYRO3_XENTR Tyrosine-protein kinase receptor TYRO3 OS=Xenopus tropicalis OX=8364 GN=tyro3 PE=2 SV=1 Length=881 Score = 251 bits (642), Expect = 2e-68, Method: Composition-based stats. Identities = 89/293 (30%), Positives = 134/293 (46%), Gaps = 28/293 (10%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG-PQHRSGWKQEIDIL 951 ++ R LG+G FG V D T + VAVK LKA+ + +E + Sbjct 499 QQQQFTLGRTLGKGEFGSVREAQLK-MEDDTMQKVAVKMLKAEIFCSSDIEEFLREAAFM 557 Query 952 RTLYHEHIIKYKGC-CEDQGEKSL---QLVMEYVPLGSLRDYLPRHSIGLA-------QL 1000 + H ++ K G + + L +++ ++ G L +L IG L Sbjct 558 KEFDHPNVCKLIGVSLRSRTKGRLPVPMVILPFMKHGDLHTFLLMSRIGEEPIALPIQTL 617 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 + F IC GM YL ++++IHRDLA RN +L+ D V + DFGL+K + G +YYR Sbjct 618 VRFMIDICSGMEYLSSKNFIHRDLATRNCMLNEDMTVCVADFGLSKKIYSG-DYYRQGCA 676 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 PV W A E L + + SDVW+FGVTL+E++T + Sbjct 677 SKLPVKWLALESLADNVYTVHSDVWAFGVTLWEIVTRGQ--------------TPYAGVE 722 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + L G RL +P C E+Y +M CW TE RP+F +L L+ + Sbjct 723 NSEIYSYLTAGNRLKQPPDCLDELYEMMCQCWITEPKRRPSFVDLKRRLEAIW 775 Score = 223 bits (568), Expect = 6e-59, Method: Composition-based stats. Identities = 71/314 (23%), Positives = 122/314 (39%), Gaps = 51/314 (16%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S+L + Q++ T LG+G +V E +L++E Sbjct 491 SKLKDVLIQQQQFTLGRTLGKGEFGSVREAQLKMED---------------------DTM 529 Query 637 LRVVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTE 688 +V +K+L F A+ M + H ++ + GV +R P +++ Sbjct 530 QKVAVKMLKAEIFCSSDIEEFLREAAFMKEFDHPNVCKLIGVSLRSRTKGRLPVPMVILP 589 Query 689 YVEHGPLDVWLRRERG-----HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 +++HG L +L R +P+ + + S + YL +KN +H ++ RN +L Sbjct 590 FMKHGDLHTFLLMSRIGEEPIALPIQTLVRFMIDICSGMEYLSSKNFIHRDLATRNCMLN 649 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDK 797 + ++D G+ S + + + WLA E L + D Sbjct 650 E-------DMTVCVADFGLSKKIYSGDYYRQGCASKLPVKWLALESLADNV--YTVHSDV 700 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855 W FG TL EI G+ P SE + +RL P +L + QC EP + Sbjct 701 WAFGVTLWEIVTRGQTPYAGVENSEIYSYLTAGNRLKQPPDCLDELYEMMCQCWITEPKR 760 Query 856 RPSFRTILRDLTRL 869 RPSF + R L + Sbjct 761 RPSFVDLKRRLEAI 774 >sp|Q10656|EGL15_CAEEL Myoblast growth factor receptor egl-15 OS=Caenorhabditis elegans OX=6239 GN=egl-15 PE=1 SV=1 Length=1040 Score = 254 bits (648), Expect = 2e-68, Method: Composition-based stats. Identities = 99/337 (29%), Positives = 153/337 (45%), Gaps = 52/337 (15%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 + N + + + + + L + LGEG FG+V Y T + VAV Sbjct 613 KRMNSENTVLSEYEVDSDPVWEVERSKLSLVHMLGEGAFGEVWKATYKETENNE-IAVAV 671 Query 930 KALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 K LK + E++ + + HE++++ GCC G L +V+E G+LRD Sbjct 672 KKLKMSAHEKELIDLVSEMETFKVIGEHENVLRLIGCCT--GAGPLYVVVELCKHGNLRD 729 Query 989 YLPRHSIGLA---------------------------------QLLLFAQQICEGMAYLH 1015 +L H L+ FA Q+ +GM +L Sbjct 730 FLRAHRPKEEKAKKSSQELTDYLEPRKASDKDDIELIPNLTQRHLVQFAWQVAQGMNFLA 789 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 ++ IHRDLAARNVL+ + ++KI DFGL++ V ++YYR R +G P+ W A E L Sbjct 790 SKKIIHRDLAARNVLVGDGHVLKISDFGLSRDV-HCNDYYRKRGNGRLPIKWMALEALDS 848 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + SDVWS+GV L+E++T L G + + L L+ G R+ Sbjct 849 NVYTVESDVWSYGVLLWEIMT--------------LGGTPYPTIAMPELYANLKEGYRME 894 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P CP EVYHLM +CW + RP+F+ ++ L + Sbjct 895 PPHLCPQEVYHLMCSCWREKLEERPSFKTIVDYLDWM 931 Score = 215 bits (547), Expect = 8e-56, Method: Composition-based stats. Identities = 70/364 (19%), Positives = 126/364 (35%), Gaps = 76/364 (21%) Query 555 PGETSNLIIMRGARASPRTLNLSQLSF-----HRVDQKEITQLSHLGQGTRTNVYEGRLR 609 P + R + LS+ V++ +++ + LG+G V++ + Sbjct 601 PITKKEAARKQRKRMNSENTVLSEYEVDSDPVWEVERSKLSLVHMLGEGAFGEVWKATYK 660 Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQV-SH 667 E+ V +K L S H+ L + H Sbjct 661 ET---------------------ENNEIAVAVKKLKMSAHEKELIDLVSEMETFKVIGEH 699 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH---------------------- 705 ++ + G C +V E +HG L +LR R Sbjct 700 ENVLRLIGCCTGAGPLYVVVELCKHGNLRDFLRAHRPKEEKAKKSSQELTDYLEPRKASD 759 Query 706 -------VPMAWK--MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 + + + A Q+A +++L +K ++H ++ RN+L+ G +K Sbjct 760 KDDIELIPNLTQRHLVQFAWQVAQGMNFLASKKIIHRDLAARNVLV-------GDGHVLK 812 Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +SD G+ + +R I W+A E L + D W +G L EI Sbjct 813 ISDFGLSRDVHCNDYYRKRGNGRLPIKWMALEALDSNV--YTVESDVWSYGVLLWEIMTL 870 Query 811 GEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTR 868 G P + + E + +R+ P CPQ + L C + +RPSF+TI+ L Sbjct 871 GGTPYPTIAMPELYANLKEGYRMEPPHLCPQEVYHLMCSCWREKLEERPSFKTIVDYLDW 930 Query 869 LQPH 872 + Sbjct 931 MLTM 934 >sp|Q0D5R2|CRK10_ORYSJ Cysteine-rich receptor-like protein kinase 10 OS=Oryza sativa subsp. japonica OX=39947 GN=CRK10 PE=2 SV=1 Length=645 Score = 246 bits (628), Expect = 2e-68, Method: Composition-based stats. Identities = 78/326 (24%), Positives = 125/326 (38%), Gaps = 17/326 (5%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 R L T + ++ + + + LGEG FG V Sbjct 305 CSTSWRRRRLARKTLRPKSSEDEMQSFASLVLDLQTLRTATDNFSEHKRLGEGGFGVVYK 364 Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 + G+ +AVK L A Q K E+ ++ L H ++++ G C ++ EK Sbjct 365 G-----DLPEGQEIAVKRL-AQTSRQGIEELKTELLLVAKLNHNNLVRLIGVCLEENEKI 418 Query 974 LQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAA 1026 L EY+P SL L + Q I G+ YLH +HRDL A Sbjct 419 LA--YEYMPNRSLDTILFDAERIKELDWGQRFKIINGIARGLQYLHEDSQLKIVHRDLKA 476 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 NVLLD+ KI DFGLAK + +PE ++ DV+S Sbjct 477 SNVLLDSAYNPKISDFGLAKIFERDQSQVITHRIA-GTYGYMSPEYAMRGQYSMKLDVYS 535 Query 1087 FGVTLYELLTHCDSSQSPPTKF-LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 FGV + E++T + S + ++LI + T + EL++ P + Sbjct 536 FGVLVLEIITGRRNFGSYGSDHVVDLIYVTWEHWTSDKAIELIDPSLGNHYPVDKVLKCI 595 Query 1146 HLMKNCWETEASFRPTFENLIPILKT 1171 H+ C + + + RP + +L + Sbjct 596 HIGLLCVQPKPADRPLMSAVNAMLSS 621 Score = 215 bits (548), Expect = 7e-58, Method: Composition-based stats. Identities = 53/316 (17%), Positives = 100/316 (32%), Gaps = 62/316 (20%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 L R ++ LG+G VY+G L Sbjct 337 DLQTLRTATDNFSEHKRLGEGGFGVVYKGDLPEGQ------------------------- 371 Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 + +K L + L+++++H +L + GVC+ E I+ EY+ + LD Sbjct 372 EIAVKRLAQTSRQGIEELKTELLLVAKLNHNNLVRLIGVCLEENEKILAYEYMPNRSLDT 431 Query 698 WLRRER--GHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752 L + + + +A L YL +VH ++ N+LL ++ Sbjct 432 ILFDAERIKELDWGQRFKIINGIARGLQYLHEDSQLKIVHRDLKASNVLLD-------SA 484 Query 753 PFIKLSDPGVGLGALSREERV------ERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 K+SD G+ + +V +++PE G S +D + FG +LE Sbjct 485 YNPKISDFGLAKIFERDQSQVITHRIAGTYGYMSPEYAMRG--QYSMKLDVYSFGVLVLE 542 Query 807 ICFDGE---------------APLQSRSPSEKEHFYQR--QHRLPEPSCPQLATLTSQCL 849 I + + + + P + + C+ Sbjct 543 IITGRRNFGSYGSDHVVDLIYVTWEHWTSDKAIELIDPSLGNHYPVDKVLKCIHIGLLCV 602 Query 850 TYEPTQRPSFRTILRD 865 +P RP + Sbjct 603 QPKPADRPLMSAVNAM 618 >sp|P15127|INSR_RAT Insulin receptor OS=Rattus norvegicus OX=10116 GN=Insr PE=1 SV=1 Length=1383 Score = 256 bits (654), Expect = 2e-68, Method: Composition-based stats. Identities = 90/304 (30%), Positives = 146/304 (48%), Gaps = 29/304 (10%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGP 938 D + + +R+LG+G FG V G E VAVK + Sbjct 1007 FPSSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEVETRVAVKTVNESASL 1066 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------- 991 + R + E +++ H+++ G +G+ +L +VME + G L+ +L Sbjct 1067 RERIEFLNEASVMKGFTCHHVVRLLGVV-SKGQPTL-VVMELMAHGDLKSHLRSLRPDAE 1124 Query 992 ----RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 R L +++ +I +GMAYL+A+ ++HRDLAARN ++ +D VKIGDFG+ + Sbjct 1125 NNPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRD 1184 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + E +YYR G PV W +PE LK+ F +SD+WSFGV L+E+ + Sbjct 1185 IYE-TDYYRKGGKGLLPVRWMSPESLKDGVFTASSDMWSFGVVLWEITS----------- 1232 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L ++ ++ + + G L PD CP + LM+ CW+ RPTF ++ Sbjct 1233 ---LAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVN 1289 Query 1168 ILKT 1171 +LK Sbjct 1290 LLKD 1293 Score = 250 bits (639), Expect = 1e-66, Method: Composition-based stats. Identities = 97/519 (19%), Positives = 179/519 (34%), Gaps = 82/519 (16%) Query 438 VAPPRLVMSIRDGIHGPLLEPF----VQAKLRPED----GLYLIHW-STSHPYRLILTVA 488 V+ + + D I GP+ V + E GL +++ S L + Sbjct 841 VSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLC 900 Query 489 QRSQAPDGMQSLRLRKFPIEQ-----------------QDGAFVLEGWGRSFPSVREL-- 529 + + RLR + F + + ++ ++ Sbjct 901 VSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIII 960 Query 530 --GAALQGCLLRAGDDCFSLRRCCLPQPGE----TSNLIIMRGARASPRTLNLSQLSFHR 583 + + G LR+ P +SN + + P ++ + Sbjct 961 GPLIFVFLFSVVIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVP--DEWE 1018 Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V +++IT L LGQG+ VYEG + G+ E RV +K Sbjct 1019 VPREKITLLRELGQGSFGMVYEGNAKDIIKGEV-------------------ETRVAVKT 1059 Query 644 LDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR- 701 ++ S + F AS+M + H+ + GV +G ++V E + HG L LR Sbjct 1060 VNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSHLRSL 1119 Query 702 --------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 R + + + ++A ++YL K VH ++ RN ++A Sbjct 1120 RPDAENNPGRPPPTLQEMIQMTAEIADGMAYLNAKKFVHRDLAARNCMVAH-------DF 1172 Query 754 FIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+ D G+ + + + W++PE L G + + D W FG L EI Sbjct 1173 TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGV--FTASSDMWSFGVVLWEI 1230 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 E P Q S + F L P+ +L L C + P RP+F I+ Sbjct 1231 TSLAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWQFNPKMRPTFLEIVNL 1290 Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 L + +V + + + + + + ++ Sbjct 1291 LKDDLHPSFPEVSFFYSEENKAPESEELEMEFEDMENVP 1329 >sp|Q95ZV7|DDRB_CAEEL Discoidin domain-containing receptor tyrosine kinase B OS=Caenorhabditis elegans OX=6239 GN=ddr-2 PE=1 SV=1 Length=797 Score = 249 bits (637), Expect = 2e-68, Method: Composition-based stats. Identities = 89/276 (32%), Positives = 145/276 (53%), Gaps = 18/276 (7%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 + +G+G FG+V L + VAVK L + +EI +L +L H + Sbjct 529 CVSRIGQGEFGEVDLCQLE------NRKVAVKKL-HGISQADEFSFHREIRVLGSLKHPN 581 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQ 1017 +++ G C Q K + +MEY+ G L+ Y+ ++ I +Q + Q+ G+AYL + Sbjct 582 VVEVVGVCTIQ--KPILCIMEYMENGDLKSYILKNPTIQTSQCISICTQLAAGLAYLESC 639 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +++HRD+AARN L+D + VKI DFG+A+++ EYY+V P+ W A E L K Sbjct 640 NFVHRDIAARNCLVDGEGNVKIADFGMARSLY-SQEYYKVEGKFVLPIRWMAWEALLLGK 698 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 F ASDVW FGVT++E+ + C +++ Q + L ++ L RP Sbjct 699 FSTASDVWGFGVTMWEIFSLCSEKPYSDMTDDDVVENLQSMSSTGSLKQV------LSRP 752 Query 1138 DKCPCEVY-HLMKNCWETEASFRPTFENLIPILKTV 1172 CP ++Y + CW E+S RP+FEN+ L+++ Sbjct 753 RMCPSKLYNEQILPCWNYESSRRPSFENVHLHLQSL 788 Score = 214 bits (544), Expect = 2e-56, Method: Composition-based stats. Identities = 70/316 (22%), Positives = 118/316 (37%), Gaps = 53/316 (17%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 + + + ++ +S +GQG V +L + +V Sbjct 518 TLPEIARDKLICVSRIGQGEFGEVDLCQL--------------------------ENRKV 551 Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +K L +F+ ++ + H ++ V GVC + + EY+E+G L ++ Sbjct 552 AVKKLHGISQADEFSFHREIRVLGSLKHPNVVEVVGVCTIQKPILCIMEYMENGDLKSYI 611 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + + + + + QLA+ L+YLE+ N VH ++ RN L+ G +K++D Sbjct 612 LKN-PTIQTSQCISICTQLAAGLAYLESCNFVHRDIAARNCLVDGEG-------NVKIAD 663 Query 760 PGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF-DGE 812 G+ S+E V I W+A E L G STA D WGFG T+ EI E Sbjct 664 FGMARSLYSQEYYKVEGKFVLPIRWMAWEALLLG--KFSTASDVWGFGVTMWEIFSLCSE 721 Query 813 APLQSRSPSEKEH----------FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 P + + Q R C YE ++RPSF + Sbjct 722 KPYSDMTDDDVVENLQSMSSTGSLKQVLSRPRMCPSKLYNEQILPCWNYESSRRPSFENV 781 Query 863 LRDLTRLQPHNLADVL 878 L L + Sbjct 782 HLHLQSLVHTSPHIHF 797 >sp|O65482|CRK23_ARATH Putative cysteine-rich receptor-like protein kinase 23 OS=Arabidopsis thaliana OX=3702 GN=CRK23 PE=2 SV=1 Length=830 Score = 250 bits (639), Expect = 2e-68, Method: Composition-based stats. Identities = 72/282 (26%), Positives = 116/282 (41%), Gaps = 18/282 (6%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 I LG+G FG+V + +G VAVK L G R ++ E+ ++ L H + Sbjct 510 PINKLGQGGFGEVYKGTF-----PSGVQVAVKRLSKTSGQGERE-FENEVVVVAKLQHRN 563 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYL 1014 +++ G C + EK LV E+V SL +L + + + I G+ YL Sbjct 564 LVRLLGYCLEGEEK--ILVYEFVHNKSLDYFLFDTTMKRQLDWTRRYKIIGGIARGILYL 621 Query 1015 HAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 H IHRDL A N+LLD D K+ DFG+A+ R + APE Sbjct 622 HQDSRLTIIHRDLKAGNILLDADMNPKVADFGMARIFGMDQTEANTRR-VVGTYGYMAPE 680 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLTELLE 1129 +F SDV+SFGV ++E+++ +S L+ + +L++ Sbjct 681 YAMYGQFSMKSDVYSFGVLVFEIISGMKNSSLYQMDDSVSNLVTYTWRLWSNGSQLDLVD 740 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 H+ C + + RP ++ +L T Sbjct 741 PSFGDNYQTHDITRCIHIALLCVQEDVDDRPNMSAIVQMLTT 782 Score = 230 bits (587), Expect = 1e-61, Method: Composition-based stats. Identities = 56/324 (17%), Positives = 104/324 (32%), Gaps = 65/324 (20%) Query 573 TLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 T Q F + ++ LGQG VY+G Sbjct 490 TAGSLQFDFKAIVAATNNFLPINKLGQGGFGEVYKGT----------------------- 526 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 ++V +K L + F +++++ H +L + G C+ G E I+V E+V Sbjct 527 --FPSGVQVAVKRLSKTSGQGEREFENEVVVVAKLQHRNLVRLLGYCLEGEEKILVYEFV 584 Query 691 EHGPLDVWLRRE--RGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745 + LD +L + + + + +A + YL + ++H ++ NILL Sbjct 585 HNKSLDYFLFDTTMKRQLDWTRRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNILLD-- 642 Query 746 GLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 K++D G+ + V ++APE G S D + Sbjct 643 -----ADMNPKVADFGMARIFGMDQTEANTRRVVGTYGYMAPEYAMYG--QFSMKSDVYS 695 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC------PQLAT---------- 843 FG + EI + + + RL P Sbjct 696 FGVLVFEIISGMKNSSLYQMDDSVSNLVTYTWRLWSNGSQLDLVDPSFGDNYQTHDITRC 755 Query 844 --LTSQCLTYEPTQRPSFRTILRD 865 + C+ + RP+ I++ Sbjct 756 IHIALLCVQEDVDDRPNMSAIVQM 779 >sp|Q8W4G6|CRK15_ARATH Cysteine-rich receptor-like protein kinase 15 OS=Arabidopsis thaliana OX=3702 GN=CRK15 PE=2 SV=2 Length=627 Score = 246 bits (627), Expect = 2e-68, Method: Composition-based stats. Identities = 71/294 (24%), Positives = 118/294 (40%), Gaps = 17/294 (6%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 + +G+G FG+V + G VAVK L G Q + +K Sbjct 326 DYRMIRAATNKFSENNKIGQGGFGEVYKGTF-----SNGTEVAVKRLSKSSG-QGDTEFK 379 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLL 1001 E+ ++ L H ++++ G GE+ LV EY+P SL +L ++ + + Sbjct 380 NEVVVVAKLQHRNLVRLLGFSIGGGER--ILVYEYMPNKSLDYFLFDPAKQNQLDWTRRY 437 Query 1002 LFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 I G+ YLH IHRDL A N+LLD D K+ DFGLA+ Sbjct 438 KVIGGIARGILYLHQDSRLTIIHRDLKASNILLDADMNPKLADFGLARIFGMDQTQENTS 497 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQG 1117 + APE +F SDV+SFGV + E+++ ++S +L+ A Sbjct 498 R-IVGTFGYMAPEYAIHGQFSVKSDVYSFGVLVLEIISGKKNNSFYETDGAHDLVTHAWR 556 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + +L++ H+ C + + + RP + +L + Sbjct 557 LWSNGTALDLVDPIIIDNCQKSEVVRCIHICLLCVQEDPAERPILSTIFMMLTS 610 Score = 236 bits (601), Expect = 6e-65, Method: Composition-based stats. Identities = 72/376 (19%), Positives = 120/376 (32%), Gaps = 70/376 (19%) Query 519 WGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQ 578 W + V + L LL CF+ R + N G + +L L Sbjct 273 WNSNVLVVAIVLTILVAALLLIAGYCFAKRVK-----NSSDNAPAFDGDDITTESLQL-D 326 Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 R + ++ + +GQG VY+G Sbjct 327 YRMIRAATNKFSENNKIGQGGFGEVYKGT-------------------------FSNGTE 361 Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V +K L S F +++++ H +L + G + G E I+V EY+ + LD + Sbjct 362 VAVKRLSKSSGQGDTEFKNEVVVVAKLQHRNLVRLLGFSIGGGERILVYEYMPNKSLDYF 421 Query 699 LRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSP 753 L + W + V +A + YL + ++H ++ NILL Sbjct 422 LFDPAKQNQLDWTRRYKVIGGIARGILYLHQDSRLTIIHRDLKASNILLD-------ADM 474 Query 754 FIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 KL+D G+ + V ++APE G S D + FG +LEI Sbjct 475 NPKLADFGLARIFGMDQTQENTSRIVGTFGYMAPEYAIHG--QFSVKSDVYSFGVLVLEI 532 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLP------EPSCPQLAT------------LTSQCL 849 G+ RL + P + + C+ Sbjct 533 IS-GKKNNSFYETDGAHDLVTHAWRLWSNGTALDLVDPIIIDNCQKSEVVRCIHICLLCV 591 Query 850 TYEPTQRPSFRTILRD 865 +P +RP TI Sbjct 592 QEDPAERPILSTIFMM 607 >sp|Q41328|PTI1_SOLLC Pto-interacting protein 1 OS=Solanum lycopersicum OX=4081 GN=PTI1 PE=1 SV=2 Length=354 Score = 237 bits (604), Expect = 2e-68, Method: Composition-based stats. Identities = 75/284 (26%), Positives = 124/284 (44%), Gaps = 24/284 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG +G+V +G A+K L D Q + ++ ++ L E++++ Sbjct 74 IGEGSYGRVYHGVLK-----SGRAAAIKKL--DSSKQPDREFLAQVSMVSRLKDENVVEL 126 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------IGLAQLLLFAQQICEGMA 1012 G C D G + L EY P GSL D L + AQ + A +G+ Sbjct 127 LGYCVDGGFR--VLAYEYAPNGSLHDILHGRKGVKGAQPGPVLSWAQRVKIAVGAAKGLE 184 Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH + H IHRD+ + N+LL +D + KI DF L+ P+ ++A Sbjct 185 YLHEKAQPHIIHRDIKSSNILLFDDDVAKIADFDLSNQAPD-MAARLHSTRVLGTFGYHA 243 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE + SDV+SFGV L ELLT + P L+ A +++ ++ + + Sbjct 244 PEYAMTGQLSSKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATPRLSEDKVKQCV 303 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + P K ++ + C + EA FRP ++ L+ + Sbjct 304 DARLNTDYPPKAIAKMAAVAALCVQYEADFRPNMSIVVKALQPL 347 Score = 209 bits (531), Expect = 2e-58, Method: Composition-based stats. Identities = 59/312 (19%), Positives = 106/312 (34%), Gaps = 59/312 (19%) Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLS-------HLGQGTRTNVYEGRL 608 G A+ +T+N+ ++ + E+ ++ +G+G+ VY G L Sbjct 28 GNNGGQRATESAQRETQTVNIQPIAVPSIAVDELKDITDNFGSKALIGEGSYGRVYHGVL 87 Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHT 668 + +K LD S F S++S++ Sbjct 88 KSGR-------------------------AAAIKKLD-SSKQPDREFLAQVSMVSRLKDE 121 Query 669 HLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG--------HVPMAWKMVVAQQLAS 720 ++ + G CV G ++ EY +G L L +G + A ++ +A A Sbjct 122 NVVELLGYCVDGGFRVLAYEYAPNGSLHDILHGRKGVKGAQPGPVLSWAQRVKIAVGAAK 181 Query 721 ALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG------LGALSREE 771 L YL K +++H ++ NILL K++D + L Sbjct 182 GLEYLHEKAQPHIIHRDIKSSNILL-------FDDDVAKIADFDLSNQAPDMAARLHSTR 234 Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 + + APE G LS+ D + FG LLE+ + + ++ Sbjct 235 VLGTFGYHAPEYAMTG--QLSSKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSLVTWATP 292 Query 832 RLPEPSCPQLAT 843 RL E Q Sbjct 293 RLSEDKVKQCVD 304 >sp|O65468|CRK8_ARATH Cysteine-rich receptor-like protein kinase 8 OS=Arabidopsis thaliana OX=3702 GN=CRK8 PE=3 SV=2 Length=676 Score = 246 bits (629), Expect = 3e-68, Method: Composition-based stats. Identities = 74/279 (27%), Positives = 118/279 (42%), Gaps = 17/279 (6%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G FG+V + G+ VAVK L + Q + +K E+ ++ L H +++ Sbjct 357 NKIGRGGFGEVYKGTF-----SNGKEVAVKRLSKN-SRQGEAEFKTEVVVVAKLQHRNLV 410 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016 + G QGE+ + LV EY+P SL L + + Q I G+ YLH Sbjct 411 RLLG-FSLQGEERI-LVYEYMPNKSLDCLLFDPTKQTQLDWMQRYNIIGGIARGILYLHQ 468 Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRDL A N+LLD D KI DFG+A+ + APE Sbjct 469 DSRLTIIHRDLKASNILLDADINPKIADFGMARIFGLDQTQDNTSR-IVGTYGYMAPEYA 527 Query 1074 KEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 +F SDV+SFGV + E+++ +SS +L+ T +L++ Sbjct 528 MHGQFSMKSDVYSFGVLVLEIISGRKNSSFDESDGAQDLLTHTWRLWTNRTALDLVDPLI 587 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + H+ C + + + RPT + +L + Sbjct 588 ANNCQNSEVVRCIHIGLLCVQEDPAKRPTISTVFMMLTS 626 Score = 230 bits (587), Expect = 9e-63, Method: Composition-based stats. Identities = 62/353 (18%), Positives = 118/353 (33%), Gaps = 67/353 (19%) Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRT 601 CF +R + +T++ + A+ +L L + + + + +G+G Sbjct 309 GYCFLAQR--TKKTFDTASASEVGDDMATADSLQL-DYRTIQTATNDFAESNKIGRGGFG 365 Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL 661 VY+G V +K L + F + Sbjct 366 EVYKGTFSNGK-------------------------EVAVKRLSKNSRQGEAEFKTEVVV 400 Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLA 719 ++++ H +L + G ++G E I+V EY+ + LD L + W + + +A Sbjct 401 VAKLQHRNLVRLLGFSLQGEERILVYEYMPNKSLDCLLFDPTKQTQLDWMQRYNIIGGIA 460 Query 720 SALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSRE 770 + YL + ++H ++ NILL K++D G+ + Sbjct 461 RGILYLHQDSRLTIIHRDLKASNILLD-------ADINPKIADFGMARIFGLDQTQDNTS 513 Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 V ++APE G S D + FG +LEI G + Sbjct 514 RIVGTYGYMAPEYAMHG--QFSMKSDVYSFGVLVLEIIS-GRKNSSFDESDGAQDLLTHT 570 Query 831 HRLP------EPSCPQLAT------------LTSQCLTYEPTQRPSFRTILRD 865 RL + P +A + C+ +P +RP+ T+ Sbjct 571 WRLWTNRTALDLVDPLIANNCQNSEVVRCIHIGLLCVQEDPAKRPTISTVFMM 623 >sp|Q9SA25|WAKLG_ARATH Wall-associated receptor kinase-like 8 OS=Arabidopsis thaliana OX=3702 GN=WAKL8 PE=2 SV=1 Length=720 Score = 247 bits (631), Expect = 3e-68, Method: Composition-based stats. Identities = 76/284 (27%), Positives = 129/284 (45%), Gaps = 18/284 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G G V + G +VAVK KA ++ + EI +L + H +++K Sbjct 396 LGQGGQGTVYKGMLE-----DGMIVAVKKSKA-LKEENLEEFINEIILLSQINHRNVVKI 449 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGMAYLHAQ- 1017 GCC + E + LV E++P +L D+L + L A ++ + ++YLH+ Sbjct 450 LGCCLE-TEVPI-LVYEFIPNRNLFDHLHNPSEDFPMSWEVRLCIACEVADALSYLHSAV 507 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 HRD+ + N+LLD K+ DFG++++V + + + + PE L+ Sbjct 508 SIPIYHRDVKSTNILLDEKHRAKVSDFGISRSVAIDDTH--LTTIVQGTIGYVDPEYLQS 565 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ-MTVLRLTELLERGERL 1134 F SDV+SFGV L ELLT + + ++G + M RL E+L+ + Sbjct 566 NHFTGKSDVYSFGVLLIELLTGEKPVSLLRRQEVRMLGAYFLEAMRNDRLHEILDARIKE 625 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 + V L + C + RPT ++ L + K +G Sbjct 626 ECDREEVLAVAKLARRCLSLNSEHRPTMRDVFIELDRMQSKRKG 669 Score = 219 bits (559), Expect = 8e-59, Method: Composition-based stats. Identities = 70/349 (20%), Positives = 118/349 (34%), Gaps = 63/349 (18%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 LGQG + VY+G L + V +K Sbjct 386 ATDRFNASRILGQGGQGTVYKGMLEDG-------------------------MIVAVKKS 420 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + F L+SQ++H ++ + G C+ I+V E++ + L L Sbjct 421 KALKEENLEEFINEIILLSQINHRNVVKILGCCLETEVPILVYEFIPNRNLFDHLHNPSE 480 Query 705 HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 PM+W ++ +A ++A ALSYL + + H +V NILL K+SD Sbjct 481 DFPMSWEVRLCIACEVADALSYLHSAVSIPIYHRDVKSTNILLDEK-------HRAKVSD 533 Query 760 PGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ + + I ++ PE L +N + D + FG L+E+ GE P Sbjct 534 FGISRSVAIDDTHLTTIVQGTIGYVDPEYLQ--SNHFTGKSDVYSFGVLLIELL-TGEKP 590 Query 815 LQSRSPSEKEHFY------QRQHRLPEPSCPQL------------ATLTSQCLTYEPTQR 856 + E R RL E ++ A L +CL+ R Sbjct 591 VSLLRRQEVRMLGAYFLEAMRNDRLHEILDARIKEECDREEVLAVAKLARRCLSLNSEHR 650 Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 P+ R + +L R+Q + + + Sbjct 651 PTMRDVFIELDRMQSKRKGTQSQAQNGEEHAHIQIAMPESMSLSYSSPN 699 >sp|P13368|7LESS_DROME Protein sevenless OS=Drosophila melanogaster OX=7227 GN=sev PE=1 SV=2 Length=2554 Score = 256 bits (654), Expect = 4e-68, Method: Composition-based stats. Identities = 79/367 (22%), Positives = 142/367 (39%), Gaps = 42/367 (11%) Query 557 ETSNLIIMRGARASPRTLNLSQLSF-HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615 +T ++ RA TL+ + ++ +++ ++ L LG G VYEG+L+ E S + Sbjct 2176 QTQQQLMAVRNRAFSTTLSDADIALLPQINWSQLKLLRFLGSGAFGEVYEGQLKTEDSEE 2235 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675 P+ RV +K L + A + A LMS H ++ + G Sbjct 2236 PQ--------------------RVAIKSLRKGASEFA-ELLQEAQLMSNFKHENIVCLVG 2274 Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRERGH----------VPMAWKMVVAQQLASALSYL 725 +C ++ E++E G L +LR R + ++ + + +A+ SYL Sbjct 2275 ICFDTESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMCIDVANGCSYL 2334 Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPWL 779 E+ + VH ++ RN L+ + +K+ D G+ + + + W+ Sbjct 2335 EDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDYYRKEGEGLLPVRWM 2394 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPS 837 +PE L G +T D W FG EI G+ P +R+ E + RL P Sbjct 2395 SPESLVDGL--FTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEGGRLQQPPMC 2452 Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897 +L +L C +P +RPSFR L + + + + Sbjct 2453 TEKLYSLLLLCWRTDPWERPSFRRCYNTLHAISTDLRRTQMASATADTVVSCSRPEFKVR 2512 Query 898 KKIRDLG 904 + L Sbjct 2513 FDGQPLE 2519 Score = 253 bits (645), Expect = 5e-67, Method: Composition-based stats. Identities = 90/290 (31%), Positives = 134/290 (46%), Gaps = 38/290 (13%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG G FG+V + + VA+K+L+ G + QE ++ HE+I+ Sbjct 2214 FLGSGAFGEVYEGQLKTEDSEEPQRVAIKSLRK--GASEFAELLQEAQLMSNFKHENIVC 2271 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL------------PRHSIGLAQLLLFAQQICE 1009 G C D +S+ L+ME++ G L YL P + L++LL + Sbjct 2272 LVGICFDT--ESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMCIDVAN 2329 Query 1010 GMAYLHAQHYIHRDLAARNVLL-------DNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 G +YL H++HRDLA RN L+ D R VKIGDFGLA+ + + +YYR +G Sbjct 2330 GCSYLEDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKS-DYYRKEGEGL 2388 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 PV W +PE L + F SDVW+FGV +E+LT L Sbjct 2389 LPVRWMSPESLVDGLFTTQSDVWAFGVLCWEILT--------------LGQQPYAARNNF 2434 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + ++ G RL +P C ++Y L+ CW T+ RP+F L + Sbjct 2435 EVLAHVKEGGRLQQPPMCTEKLYSLLLLCWRTDPWERPSFRRCYNTLHAI 2484 >sp|C0LGG8|Y5343_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g53430 OS=Arabidopsis thaliana OX=3702 GN=At1g53430 PE=1 SV=1 Length=1038 Score = 253 bits (645), Expect = 4e-68, Method: Composition-based stats. Identities = 77/285 (27%), Positives = 122/285 (43%), Gaps = 19/285 (7%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 +GEG FG V G +AVK L + Q + EI ++ L Sbjct 667 NNFDPENKIGEGGFGPVYKGVL-----ADGMTIAVKQLSSK-SKQGNREFVTEIGMISAL 720 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICE 1009 H +++K GCC + E L LV EY+ SL L R + + I + Sbjct 721 QHPNLVKLYGCCIEGKE--LLLVYEYLENNSLARALFGTEKQRLHLDWSTRNKICIGIAK 778 Query 1010 GMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G+AYLH + +HRD+ A NVLLD KI DFGLAK + + + R G + Sbjct 779 GLAYLHEESRLKIVHRDIKATNVLLDLSLNAKISDFGLAKLNDDENTHISTRIAG--TIG 836 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHC-DSSQSPPTKFLELIGIAQGQMTVLRLT 1125 + APE +DV+SFGV E+++ +++ P +F+ L+ A L Sbjct 837 YMAPEYAMRGYLTDKADVYSFGVVCLEIVSGKSNTNYRPKEEFVYLLDWAYVLQEQGSLL 896 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 EL++ K + ++ C + RP +++ +L+ Sbjct 897 ELVDPDLGTSFSKKEAMRMLNIALLCTNPSPTLRPPMSSVVSMLE 941 Score = 234 bits (596), Expect = 6e-62, Method: Composition-based stats. Identities = 70/366 (19%), Positives = 123/366 (34%), Gaps = 70/366 (19%) Query 529 LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKE 588 + AA L LR E +RG + L Q+ + Sbjct 615 VIAACAVFGLLV---LVILRLTGYLGGKEVDENEELRGLDLQTGSFTLKQI---KRATNN 668 Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 + +G+G VY+G L + + +K L Sbjct 669 FDPENKIGEGGFGPVYKGVLADG-------------------------MTIAVKQLSSKS 703 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR---RERGH 705 F ++S + H +L ++G C+ G E ++V EY+E+ L L ++R H Sbjct 704 KQGNREFVTEIGMISALQHPNLVKLYGCCIEGKELLLVYEYLENNSLARALFGTEKQRLH 763 Query 706 VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + + + + +A L+YL + +VH ++ N+LL S K+SD G+ Sbjct 764 LDWSTRNKICIGIAKGLAYLHEESRLKIVHRDIKATNVLLD-------LSLNAKISDFGL 816 Query 763 GLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + I ++APE G L+ D + FG LEI G++ Sbjct 817 AKLNDDENTHISTRIAGTIGYMAPEYAMRGY--LTDKADVYSFGVVCLEIVS-GKSNTNY 873 Query 818 RSPSEKEHFYQRQHRLPEPSC------------------PQLATLTSQCLTYEPTQRPSF 859 R E + + L E ++ + C PT RP Sbjct 874 RPKEEFVYLLDWAYVLQEQGSLLELVDPDLGTSFSKKEAMRMLNIALLCTNPSPTLRPPM 933 Query 860 RTILRD 865 +++ Sbjct 934 SSVVSM 939 >sp|P30530|UFO_HUMAN Tyrosine-protein kinase receptor UFO OS=Homo sapiens OX=9606 GN=AXL PE=1 SV=4 Length=894 Score = 250 bits (639), Expect = 5e-68, Method: Composition-based stats. Identities = 85/282 (30%), Positives = 127/282 (45%), Gaps = 29/282 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHII 960 LGEG FG V + D + VAVK +K A C + E ++ H +++ Sbjct 541 TLGEGEFGAVMEGQLN--QDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVM 598 Query 961 KYKGCCEDQGEK----SLQLVMEYVPLGSLRDYLPRHSIGLA-------QLLLFAQQICE 1009 + G C E+ + +++ ++ G L +L +G L+ F I Sbjct 599 RLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGDQPVYLPTQMLVKFMADIAS 658 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 GM YL + +IHRDLAARN +L+ + V + DFGL+K + G +YYR PV W A Sbjct 659 GMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNG-DYYRQGRIAKMPVKWIA 717 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E L + + SDVWSFGVT++E+ T + + + L Sbjct 718 IESLADRVYTSKSDVWSFGVTMWEIATRGQ--------------TPYPGVENSEIYDYLR 763 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +G RL +P C +Y LM CWE RP+F L L+ Sbjct 764 QGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTELREDLEN 805 Score = 224 bits (572), Expect = 2e-59, Method: Composition-based stats. Identities = 67/307 (22%), Positives = 117/307 (38%), Gaps = 52/307 (17%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 +L VD+ ++ LG+G V EG+L + S L Sbjct 525 KLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSI----------------------L 562 Query 638 RVVLKVLDP--SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN------IMVTEY 689 +V +K + F A M + H ++ + GVC +G E +++ + Sbjct 563 KVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPF 622 Query 690 VEHGPLDVWLRRERG-----HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 ++HG L +L R ++P + +AS + YL K +H ++ RN +L Sbjct 623 MKHGDLHSFLLYSRLGDQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNE 682 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKW 798 + + ++D G+ + + + W+A E L ++ D W Sbjct 683 -------NMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRV--YTSKSDVW 733 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 FG T+ EI G+ P SE + ++ +RL P L L S+C P R Sbjct 734 SFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQDR 793 Query 857 PSFRTIL 863 PSF + Sbjct 794 PSFTELR 800 >sp|P08923|LTK_MOUSE Leukocyte tyrosine kinase receptor OS=Mus musculus OX=10090 GN=Ltk PE=1 SV=3 Length=888 Score = 250 bits (638), Expect = 5e-68, Method: Composition-based stats. Identities = 91/391 (23%), Positives = 140/391 (36%), Gaps = 58/391 (15%) Query 516 LEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCC-------LPQPGETSNLIIMRGAR 568 L + + AAL LL + + C LP P + + R Sbjct 415 LPTTASPLILMGAVVAALALSLLMMCAVLILVNQKCQGLWGTRLPGPELELSKLRSSAIR 474 Query 569 ASPRTL----NLSQLS-------FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 +P LS V +T L LG G VYEG + Sbjct 475 TAPNPYYCQVGLSPAQPWPLPPGLTEVSPANVTLLRALGHGAFGEVYEGLV--------- 525 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGV 676 G D PL V +K L H L F A ++S+ SH ++ G+ Sbjct 526 TGLPGDSSPLP----------VAIKTLPELCSHQDELDFLMEALIISKFSHQNIVRCVGL 575 Query 677 CVRGPENIMVTEYVEHGPLDVWLRRERGH------VPMAWKMVVAQQLASALSYLENKNL 730 R +++ E + G + +LR R H + M + +AQ +A YLE + Sbjct 576 SFRSAPRLILLELMSGGDMKSFLRHSRPHPGQLAPLTMQDLLQLAQDIAQGCHYLEENHF 635 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECL 784 +H ++ RN LL+ G S K+ D G+ + + W+ PE L Sbjct 636 IHRDIAARNCLLS----CSGASRVAKIGDFGMARDIYQASYYRKGGRTLLPVKWMPPEAL 691 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLA 842 G ++ D W FG L EI G P + E F +R+ P +CP + Sbjct 692 LEGL--FTSKTDSWSFGVLLWEIFSLGYMPYPGHTNQEVLDFIATGNRMDPPRNCPGPVY 749 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 + +QC ++P RP F +IL + Sbjct 750 RIMTQCWQHQPELRPDFGSILERIQYCTQDP 780 Score = 244 bits (624), Expect = 4e-66, Method: Composition-based stats. Identities = 87/295 (29%), Positives = 129/295 (44%), Gaps = 34/295 (12%) Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG G FG+V D + VA+K L C Q + E I+ H++I++ Sbjct 512 LGHGAFGEVYEGLVTGLPGDSSPLPVAIKTLPELCSHQDELDFLMEALIISKFSHQNIVR 571 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--------SIGLAQLLLFAQQICEGMAY 1013 G + + L E + G ++ +L + + LL AQ I +G Y Sbjct 572 CVGLSFRSAPRLILL--ELMSGGDMKSFLRHSRPHPGQLAPLTMQDLLQLAQDIAQGCHY 629 Query 1014 LHAQHYIHRDLAARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 L H+IHRD+AARN LL + KIGDFG+A+ + + YYR PV W P Sbjct 630 LEENHFIHRDIAARNCLLSCSGASRVAKIGDFGMARDIYQA-SYYRKGGRTLLPVKWMPP 688 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E L E F +D WSFGV L+E+ + L + T + + + Sbjct 689 EALLEGLFTSKTDSWSFGVLLWEIFS--------------LGYMPYPGHTNQEVLDFIAT 734 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 G R+ P CP VY +M CW+ + RP F ++ L+ + Y Q P V + Sbjct 735 GNRMDPPRNCPGPVYRIMTQCWQHQPELRPDFGSI---LERIQ--YCTQDPDVLN 784 >sp|O64842|PBL12_ARATH Probable serine/threonine-protein kinase PBL12 OS=Arabidopsis thaliana OX=3702 GN=PBL12 PE=2 SV=1 Length=424 Score = 238 bits (608), Expect = 6e-68, Method: Composition-based stats. Identities = 90/339 (27%), Positives = 143/339 (42%), Gaps = 14/339 (4%) Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 C ++ ++ + + + S+ V + + LG Sbjct 37 IRTCPAFKRLSLSDISDPSSPMSVMDDLSHSFTSQKLRLFTLSELRVITHNFSRSNM-LG 95 Query 905 EGHFGKVSLYCYDPTND--GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 EG FG V D + VAVKAL HR W EI L L ++H++K Sbjct 96 EGGFGPVYKGFIDDKVKPGIEAQPVAVKALDLHGHQGHRE-WLAEILFLGQLSNKHLVKL 154 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA--Q 1017 G C ++ ++ LV EY+P GSL + L R + + + A +G+A+LH + Sbjct 155 IGFCCEEEQR--VLVYEYMPRGSLENQLFRRNSLAMAWGIRMKIALGAAKGLAFLHEAEK 212 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 I+RD N+LLD+D K+ DFGLAK PEG E+ V + APE + Sbjct 213 PVIYRDFKTSNILLDSDYNAKLSDFGLAKDGPEG-EHTHVTTRVMGTQGYAAPEYIMTGH 271 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLRLTELLERGERLPR 1136 +DV+SFGV L EL+T S + T + L+ A+ + R E + + Sbjct 272 LTTMNDVYSFGVVLLELITGKRSMDNTRTRREQSLVEWARPMLRDQRKLERIIDPRLANQ 331 Query 1137 PDKCPCEV-YHLMKNCWETEASFRPTFENLIPILKTVHE 1174 +V L C +RPT ++ +L+++ E Sbjct 332 HKTEAAQVAASLAYKCLSQHPKYRPTMCEVVKVLESIQE 370 Score = 226 bits (577), Expect = 8e-64, Method: Composition-based stats. Identities = 83/370 (22%), Positives = 143/370 (39%), Gaps = 56/370 (15%) Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P +++ + + L L LS RV ++ + LG+G VY+G + Sbjct 54 PSSPMSVMDDLSHSFTSQKLRLFTLSELRVITHNFSRSNMLGEGGFGPVYKGFI------ 107 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 +D + PG + V +K LD H + + Q+S+ HL + Sbjct 108 ---------DDKVKPGI---EAQPVAVKALDLHGHQGHREWLAEILFLGQLSNKHLVKLI 155 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE--NKNL 730 G C + ++V EY+ G L+ L R R + MAW +M +A A L++L K + Sbjct 156 GFCCEEEQRVLVYEYMPRGSLENQLFR-RNSLAMAWGIRMKIALGAAKGLAFLHEAEKPV 214 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECL 784 ++ + NILL + KLSD G+ E + + APE + Sbjct 215 IYRDFKTSNILLD-------SDYNAKLSDFGLAKDGPEGEHTHVTTRVMGTQGYAAPEYI 267 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ------RQHRLPEPSC 838 G L+T D + FG LLE+ + +R+ E+ Q +L Sbjct 268 MTG--HLTTMNDVYSFGVVLLELITGKRSMDNTRTRREQSLVEWARPMLRDQRKLERIID 325 Query 839 PQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 P+L A+L +CL+ P RP+ +++ L +Q ++ N Sbjct 326 PRLANQHKTEAAQVAASLAYKCLSQHPKYRPTMCEVVKVLESIQEVDIRKHDGNNNKEGK 385 Query 887 SDPTVFHKRY 896 + R+ Sbjct 386 KFVDINKFRH 395 >sp|A0A0P0XII1|CERK1_ORYSJ Chitin elicitor receptor kinase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=CERK1 PE=1 SV=1 Length=624 Score = 244 bits (623), Expect = 7e-68, Method: Composition-based stats. Identities = 64/285 (22%), Positives = 114/285 (40%), Gaps = 26/285 (9%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G+G FG V GE A+K + + + E+ +L ++H +++ Sbjct 328 NKIGQGGFGAVYYAELR------GEKAAIKKMDMQATHE----FLAELKVLTHVHHLNLV 377 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQ 1017 + G C E SL LV E++ G+L +L + A + A G+ Y+H Sbjct 378 RLIGYCI---ESSLFLVYEFIENGNLSQHLRGMGYEPLSWAARIQIALDSARGLEYIHEH 434 Query 1018 HY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRD+ + N+L+D + K+ DFGL K G + PE + Sbjct 435 TVPVYIHRDIKSANILIDKNYRAKVADFGLTKLTEVGGTSMPTGTRVVGTFGYMPPEYAR 494 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE-------L 1127 DV++FGV LYEL++ ++ + G+ L + L Sbjct 495 YGDVSPKVDVYAFGVVLYELISAKEAIVRSTESSSDSKGLVYLFEEALNSPDPKEGLRTL 554 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 ++ P ++ L K C + + RP+ +++ L T+ Sbjct 555 IDPKLGEDYPIDSILKLTQLAKVCTQEDPKLRPSMRSVVVALMTL 599 Score = 197 bits (502), Expect = 4e-52, Method: Composition-based stats. Identities = 66/329 (20%), Positives = 119/329 (36%), Gaps = 77/329 (23%) Query 578 QLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 + S+ + + + + +GQG VY LR E Sbjct 311 EFSYEELSNATQGFSIGNKIGQGGFGAVYYAELRGE------------------------ 346 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 + +K +D F +++ V H +L + G C+ +V E++E+G L Sbjct 347 --KAAIKKMD---MQATHEFLAELKVLTHVHHLNLVRLIGYCIESS-LFLVYEFIENGNL 400 Query 696 DVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNL---VHGNVCGRNILLARLGLAEG 750 LR G+ P++W ++ +A A L Y+ + +H ++ NIL+ + Sbjct 401 SQHLRG-MGYEPLSWAARIQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDK------ 453 Query 751 TSPFIKLSDPGV-------GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 + K++D G+ G + V ++ PE G +S +D + FG Sbjct 454 -NYRAKVADFGLTKLTEVGGTSMPTGTRVVGTFGYMPPEYARYG--DVSPKVDVYAFGVV 510 Query 804 LLEICFDGEAPLQSRSPS-----------EKEHFYQRQHRLPEPSCPQLAT--------- 843 L E+ EA ++S S E + + L P+L Sbjct 511 LYELISAKEAIVRSTESSSDSKGLVYLFEEALNSPDPKEGLRTLIDPKLGEDYPIDSILK 570 Query 844 ---LTSQCLTYEPTQRPSFRTILRDLTRL 869 L C +P RPS R+++ L L Sbjct 571 LTQLAKVCTQEDPKLRPSMRSVVVALMTL 599 >sp|Q54XQ2|RCKA_DICDI RGS domain-containing serine/threonine-protein kinase A OS=Dictyostelium discoideum OX=44689 GN=rckA PE=1 SV=1 Length=1125 Score = 253 bits (645), Expect = 7e-68, Method: Composition-based stats. Identities = 73/321 (23%), Positives = 130/321 (40%), Gaps = 31/321 (10%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 + L ++ ++ S T + + + G G+V Sbjct 800 SITLDNDEDPTIFHLDESDMESLIEEVVKDNISVHTEISYSDVSIHKWIASGSSGRVYNG 859 Query 915 CYDPTNDGTGEMVAVKALKADCGPQ-HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 Y G+ VA+K L + + +K+E+ ++ H+++ + G +K Sbjct 860 QYK------GKDVAIKVLGPEVCVHFDLNEFKREVALMSIFKHDNLARCLGA-GQYDDKY 912 Query 974 LQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031 L EY GSL YL R++I Q L FA I GM YLH+ IHRDL + N+LL Sbjct 913 FHL-TEYCHNGSLFSYLRDQRNNISFGQRLHFALGIARGMRYLHSMSIIHRDLKSMNILL 971 Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091 +KI DFG ++ + + W APE + DV+S+ + L Sbjct 972 TKRLKIKIVDFGTSRVANKYN-----MTTHVGTQAWMAPEIFTSRTYTNKVDVYSYAIIL 1026 Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 +E+ T A + + + ++ +GER P + +++K C Sbjct 1027 FEIFTRKS---------------AYDENANINIPNMVMKGERPELPKDMQTSISNIIKKC 1071 Query 1152 WETEASFRPTFENLIPILKTV 1172 W+ + S RP+F ++ L+++ Sbjct 1072 WQQKPSNRPSFIKIVAYLESI 1092 Score = 216 bits (551), Expect = 4e-56, Method: Composition-based stats. Identities = 61/297 (21%), Positives = 115/297 (39%), Gaps = 44/297 (15%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 + +++ + G+ VY G+ + + V +K Sbjct 836 EISYSDVSIHKWIASGSSGRVYNGQYKGKD--------------------------VAIK 869 Query 643 VLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 VL P H D+ F +LMS H +LA G + +TEY +G L +L Sbjct 870 VLGPEVCVHFDLN-EFKREVALMSIFKHDNLARCLGAGQYDDKYFHLTEYCHNGSLFSYL 928 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R +R ++ ++ A +A + YL + +++H ++ NILL + IK+ D Sbjct 929 RDQRNNISFGQRLHFALGIARGMRYLHSMSIIHRDLKSMNILLTK-------RLKIKIVD 981 Query 760 PGVGL--GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 G + V W+APE + + + +D + + L EI F ++ Sbjct 982 FGTSRVANKYNMTTHVGTQAWMAPEIFT--SRTYTNKVDVYSYAIILFEI-FTRKSAYDE 1038 Query 818 RSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 + + + R LP+ ++ + +C +P+ RPSF I+ L + Sbjct 1039 NANINIPNMVMKGERPELPKDMQTSISNIIKKCWQQKPSNRPSFIKIVAYLESIIYP 1095 >sp|O64783|Y1137_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61370 OS=Arabidopsis thaliana OX=3702 GN=At1g61370 PE=3 SV=2 Length=814 Score = 248 bits (633), Expect = 8e-68, Method: Composition-based stats. Identities = 71/311 (23%), Positives = 129/311 (41%), Gaps = 17/311 (5%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 + + + LG+G FG V N G+ +A+K L + G Sbjct 483 PQDVNFFDMQTILTITNNFSMENKLGQGGFGPVYKG-----NLQDGKEIAIKRLSSTSG- 536 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHS 994 Q + EI ++ L H ++++ GCC + EK L+ E++ SL ++ + Sbjct 537 QGLEEFMNEIILISKLQHRNLVRLLGCCIEGEEK--LLIYEFMANKSLNTFIFDSTKKLE 594 Query 995 IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 + + Q I G+ YLH +HRD+ N+LLD + KI DFGLA+ +G Sbjct 595 LDWPKRFEIIQGIACGLLYLHRDSCLRVVHRDMKVSNILLDEEMNPKISDFGLARMF-QG 653 Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLE 1110 ++ + + +PE F SD+++FGV L E++T SS + + Sbjct 654 TQHQANTRRVVGTLGYMSPEYAWTGMFSEKSDIYAFGVLLLEIITGKRISSFTIGEEGKT 713 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 L+ A ++LL++ + + C + +A RP ++ +L Sbjct 714 LLEFAWDSWCESGGSDLLDQDISSSGSESEVARCVQIGLLCIQQQAGDRPNIAQVMSMLT 773 Query 1171 TVHEKYQGQAP 1181 T + + + P Sbjct 774 TTMDLPKPKQP 784 Score = 230 bits (586), Expect = 1e-61, Method: Composition-based stats. Identities = 51/258 (20%), Positives = 93/258 (36%), Gaps = 45/258 (17%) Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 + P+ +N + + + LGQG VY+G L+ Sbjct 478 REQLKPQDVNFFDMQTILTITNNFSMENKLGQGGFGPVYKGNLQDGK------------- 524 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 + +K L + F L+S++ H +L + G C+ G E ++ Sbjct 525 ------------EIAIKRLSSTSGQGLEEFMNEIILISKLQHRNLVRLLGCCIEGEEKLL 572 Query 686 VTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNI 740 + E++ + L+ ++ + + W + + Q +A L YL +VH ++ NI Sbjct 573 IYEFMANKSLNTFIFDSTKKLELDWPKRFEIIQGIACGLLYLHRDSCLRVVHRDMKVSNI 632 Query 741 LLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTA 794 LL K+SD G+ + V + +++PE G S Sbjct 633 LLDEE-------MNPKISDFGLARMFQGTQHQANTRRVVGTLGYMSPEYAWTGM--FSEK 683 Query 795 MDKWGFGATLLEICFDGE 812 D + FG LLEI Sbjct 684 SDIYAFGVLLLEIITGKR 701 >sp|Q9LDQ3|CRK34_ARATH Cysteine-rich receptor-like protein kinase 34 OS=Arabidopsis thaliana OX=3702 GN=CRK34 PE=3 SV=3 Length=669 Score = 244 bits (624), Expect = 1e-67, Method: Composition-based stats. Identities = 74/278 (27%), Positives = 113/278 (41%), Gaps = 18/278 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG+V +G VAVK L G Q +K E ++ L H+++++ Sbjct 351 IGRGGFGEVYRG-----KLSSGPEVAVKRLSKTSG-QGAEEFKNEAVLVSKLQHKNLVRL 404 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 G C + EK LV E+VP SL +L + + + I G+ YLH Sbjct 405 LGFCLEGEEK--ILVYEFVPNKSLDYFLFDPAKQGELDWTRRYNIIGGIARGILYLHQDS 462 Query 1019 ---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 IHRDL A N+LLD D KI DFG+A+ R + +PE Sbjct 463 RLTIIHRDLKASNILLDADMNPKIADFGMARIFGVDQSQANTRRIA-GTFGYMSPEYAMR 521 Query 1076 YKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 F SDV+SFGV + E+++ S + L+ A EL++ Sbjct 522 GHFSMKSDVYSFGVLVLEIISGKKNSSFYNIDDSGSNLVTHAWRLWRNGSPLELVDPTIG 581 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 H+ C + + + RP +I +L + Sbjct 582 ESYQSSEATRCIHIALLCVQEDPADRPLLPAIIMMLTS 619 Score = 239 bits (610), Expect = 9e-66, Method: Composition-based stats. Identities = 61/324 (19%), Positives = 110/324 (34%), Gaps = 65/324 (20%) Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 T + Q SF ++ + + + +G+G VY G+L Sbjct 327 TTHSLQFSFKTIEAATDKFSDSNMIGRGGFGEVYRGKLSSGP------------------ 368 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 V +K L + A F A L+S++ H +L + G C+ G E I+V E+V Sbjct 369 -------EVAVKRLSKTSGQGAEEFKNEAVLVSKLQHKNLVRLLGFCLEGEEKILVYEFV 421 Query 691 EHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745 + LD +L ++G + + + +A + YL + ++H ++ NILL Sbjct 422 PNKSLDYFLFDPAKQGELDWTRRYNIIGGIARGILYLHQDSRLTIIHRDLKASNILLD-- 479 Query 746 GLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 K++D G+ + +++PE G S D + Sbjct 480 -----ADMNPKIADFGMARIFGVDQSQANTRRIAGTFGYMSPEYAMRG--HFSMKSDVYS 532 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------------QL 841 FG +LEI + + RL P + Sbjct 533 FGVLVLEIISGKKNSSFYNIDDSGSNLVTHAWRLWRNGSPLELVDPTIGESYQSSEATRC 592 Query 842 ATLTSQCLTYEPTQRPSFRTILRD 865 + C+ +P RP I+ Sbjct 593 IHIALLCVQEDPADRPLLPAIIMM 616 >sp|Q9ASQ6|Y1972_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g29720 OS=Arabidopsis thaliana OX=3702 GN=RFK1 PE=2 SV=3 Length=1019 Score = 251 bits (641), Expect = 1e-67, Method: Composition-based stats. Identities = 74/297 (25%), Positives = 119/297 (40%), Gaps = 17/297 (6%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH 940 + + LGEG FG V G ++AVK L + + Sbjct 657 QTVCFSWRQLQTATNNFDQANKLGEGGFGSVFKGEL-----SDGTIIAVKQLSSKSSQGN 711 Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGL 997 R + EI ++ L H +++K GCC ++ + L LV EY+ SL L + Sbjct 712 RE-FVNEIGMISGLNHPNLVKLYGCCVERDQ--LLLVYEYMENNSLALALFGQNSLKLDW 768 Query 998 AQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 A I G+ +LH +HRD+ NVLLD D KI DFGLA+ H + Sbjct 769 AARQKICVGIARGLEFLHDGSAMRMVHRDIKTTNVLLDTDLNAKISDFGLARLHEAEHTH 828 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC-DSSQSPPTKFLELIG 1113 + G + + APE + +DV+SFGV E+++ ++ Q + LI Sbjct 829 ISTKVAG--TIGYMAPEYALWGQLTEKADVYSFGVVAMEIVSGKSNTKQQGNADSVSLIN 886 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 A + E+++R + + C + S RPT + +L+ Sbjct 887 WALTLQQTGDILEIVDRMLEGEFNRSEAVRMIKVALVCTNSSPSLRPTMSEAVKMLE 943 Score = 220 bits (560), Expect = 2e-57, Method: Composition-based stats. Identities = 52/281 (19%), Positives = 101/281 (36%), Gaps = 47/281 (17%) Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 +R + QL Q + LG+G +V++G L Sbjct 651 LRAQGLQTVCFSWRQLQT---ATNNFDQANKLGEGGFGSVFKGELSDG------------ 695 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 + +K L F ++S ++H +L ++G CV + Sbjct 696 -------------TIIAVKQLSSKSSQGNREFVNEIGMISGLNHPNLVKLYGCCVERDQL 742 Query 684 IMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRN 739 ++V EY+E+ L + L + + A + + +A L +L + +VH ++ N Sbjct 743 LLVYEYMENNSLALALFGQNSLKLDWAARQKICVGIARGLEFLHDGSAMRMVHRDIKTTN 802 Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTA 794 +LL T K+SD G+ + + I ++APE G L+ Sbjct 803 VLLD-------TDLNAKISDFGLARLHEAEHTHISTKVAGTIGYMAPEYALWG--QLTEK 853 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 D + FG +EI G++ + + ++ L + Sbjct 854 ADVYSFGVVAMEIVS-GKSNTKQQGNADSVSLINWALTLQQ 893 >sp|O61460|VAB1_CAEEL Ephrin receptor 1 OS=Caenorhabditis elegans OX=6239 GN=vab-1 PE=1 SV=1 Length=1122 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 85/349 (24%), Positives = 133/349 (38%), Gaps = 52/349 (15%) Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916 P + + + + + + + + + +G G FG V L Sbjct 652 PYYGGVHPNSGKYKTYVDPTTYEDPYQALIEFTFDISPNDVFITQVIGGGEFGDVCLGGL 711 Query 917 DPTNDGTG-----------------------EMVAVKALKADCGPQHRSGWKQEIDILRT 953 + E VA+K LK+ + ++ + E I+ Sbjct 712 SKNSPAAAKWSVSNTTMGRGGGGGGYESEPYETVAIKTLKSGSSAKAKAEFLTEATIMGQ 771 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQIC 1008 H ++I+ G + + +V EY+ GSL +L + ++ I Sbjct 772 FSHPNVIRLIGVVTSA--EPVMIVAEYMANGSLDQFLRNTDQRGEKVHWEKITEMLYGIA 829 Query 1009 EGMAYLHAQHYIHR-----DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR---VRED 1060 GM YL Y+HR DLAARNVLLD + KI DFGL++ V Sbjct 830 SGMKYLTDMGYVHRVSFLRDLAARNVLLDMELRCKIADFGLSRGVRSEGSSVEPEYTTNG 889 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 G PV W APE + KF +SDVWSFGV ++E+ + + T Sbjct 890 GKIPVRWTAPEAITHRKFTPSSDVWSFGVVIWEVCSFGER--------------PYWDWT 935 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 ++ + G RLP P CP +Y + + CW+ E RPTF L+ Sbjct 936 NQKVISEVMIGYRLPPPMDCPMGLYRIAQWCWKMERHERPTFTQLLATF 984 Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats. Identities = 69/321 (21%), Positives = 112/321 (35%), Gaps = 33/321 (10%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL---RVV 640 + ++ +G G +V G L + + G + V Sbjct 687 ISPNDVFITQVIGGGEFGDVCLGGLSKNSPAAAKWSVSNTTMGRGGGGGGYESEPYETVA 746 Query 641 LKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +K L F A++M Q SH ++ + GV ++V EY+ +G LD +L Sbjct 747 IKTLKSGSSAKAKAEFLTEATIMGQFSHPNVIRLIGVVTSAEPVMIVAEYMANGSLDQFL 806 Query 700 RRER---GHVPMAWKMVVAQQLASALSYLENKNLVH-----GNVCGRNILLARLGLAEGT 751 R V + +AS + YL + VH ++ RN+LL Sbjct 807 RNTDQRGEKVHWEKITEMLYGIASGMKYLTDMGYVHRVSFLRDLAARNVLLD-------M 859 Query 752 SPFIKLSDPGVGLGALSREERVE----------RIPWLAPECLPGGANSLSTAMDKWGFG 801 K++D G+ G S VE + W APE + + + D W FG Sbjct 860 ELRCKIADFGLSRGVRSEGSSVEPEYTTNGGKIPVRWTAPEAITH--RKFTPSSDVWSFG 917 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-CPQ-LATLTSQCLTYEPTQRPSF 859 + E+C GE P + + +RLP P CP L + C E +RP+F Sbjct 918 VVIWEVCSFGERPYWDWTNQKVISEVMIGYRLPPPMDCPMGLYRIAQWCWKMERHERPTF 977 Query 860 RTILRDLTRLQPHNLADVLTV 880 +L + Sbjct 978 TQLLATFHKYILQPTLIEHDP 998 >sp|Q8QFP9|TYRO3_XENLA Tyrosine-protein kinase receptor TYRO3 OS=Xenopus laevis OX=8355 GN=tyro3 PE=1 SV=1 Length=880 Score = 249 bits (635), Expect = 1e-67, Method: Composition-based stats. Identities = 90/293 (31%), Positives = 134/293 (46%), Gaps = 28/293 (10%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG-PQHRSGWKQEIDIL 951 ++ R LG+G FG V D T + VAVK LKA+ + +E + Sbjct 499 QQQQFTLGRTLGKGEFGSVREAQLK-MEDDTMQKVAVKMLKAEIFCSSDIEEFLREAAFM 557 Query 952 RTLYHEHIIKYKGC-CEDQGEKSL---QLVMEYVPLGSLRDYLPRHSIGLA-------QL 1000 + H ++ K G + + L +++ ++ G L +L IG L Sbjct 558 KEFDHPNVCKLIGVSLRSRTKGRLPVPMVILPFMKHGDLHTFLLMSRIGEEPITLPVQTL 617 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 + F IC GM YL ++++IHRDLA RN +L+ D V + DFGL+K + G +YYR Sbjct 618 VRFMIDICSGMEYLSSKNFIHRDLATRNCMLNEDMTVCVADFGLSKKIYSG-DYYRQGCA 676 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 PV W A E L + + SDVW+FGVTL+E+ T L + Sbjct 677 SKLPVKWLALESLADNVYTVHSDVWAFGVTLWEIAT--------------LGQTPYAGVE 722 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + L G RL +P C E+Y +M CW TE RP+F +L L+ + Sbjct 723 NSEIYSYLIAGNRLKQPLDCLDELYEMMCQCWITEPKRRPSFVDLKQRLEAIW 775 Score = 221 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 70/314 (22%), Positives = 122/314 (39%), Gaps = 51/314 (16%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S+L + Q++ T LG+G +V E +L++E Sbjct 491 SKLKDVLIQQQQFTLGRTLGKGEFGSVREAQLKMED---------------------DTM 529 Query 637 LRVVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTE 688 +V +K+L F A+ M + H ++ + GV +R P +++ Sbjct 530 QKVAVKMLKAEIFCSSDIEEFLREAAFMKEFDHPNVCKLIGVSLRSRTKGRLPVPMVILP 589 Query 689 YVEHGPLDVWLRRERG-----HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 +++HG L +L R +P+ + + S + YL +KN +H ++ RN +L Sbjct 590 FMKHGDLHTFLLMSRIGEEPITLPVQTLVRFMIDICSGMEYLSSKNFIHRDLATRNCMLN 649 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDK 797 + ++D G+ S + + + WLA E L + D Sbjct 650 E-------DMTVCVADFGLSKKIYSGDYYRQGCASKLPVKWLALESLADNV--YTVHSDV 700 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQ 855 W FG TL EI G+ P SE + +RL P +L + QC EP + Sbjct 701 WAFGVTLWEIATLGQTPYAGVENSEIYSYLIAGNRLKQPLDCLDELYEMMCQCWITEPKR 760 Query 856 RPSFRTILRDLTRL 869 RPSF + + L + Sbjct 761 RPSFVDLKQRLEAI 774 >sp|Q54PX0|Y4251_DICDI Probable serine/threonine-protein kinase DDB_G0284251 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0284251 PE=3 SV=1 Length=496 Score = 239 bits (611), Expect = 1e-67, Method: Composition-based stats. Identities = 75/268 (28%), Positives = 126/268 (47%), Gaps = 26/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHII 960 +G G FG+V + N TGE VA+K + ++ K E++IL L H +I+ Sbjct 41 KIGRGAFGQV----FKGLNGKTGEFVAIKQIDSNKIDESSLQSVKGEVEILHKLRHNNIV 96 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHY 1019 K G E Q + L ++EYV GSLRD + + + +++ Q+ +G+AYLH+ Sbjct 97 KVLGVVEVQAQ--LNFILEYVENGSLRDVIEKFGPLSEELCIIYLYQMLQGLAYLHSNKV 154 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+L+ + ++K+ DFG+A + ++R +W APE ++ Sbjct 155 IHRDIKASNILITKEGVIKLADFGVASQIDSES---QLRFSVVGTPYWMAPESIEISGCS 211 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 ASD+WS G T+ ELLT + Q + R+ + P P Sbjct 212 SASDIWSLGSTMIELLTGNPPYYT-----------LQPMAAMFRIVS----DQHPPFPTD 256 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 E + ++ + + RPT + L+ Sbjct 257 ISKEFLDYFQQSFKKDPTQRPTAQELLQ 284 Score = 205 bits (521), Expect = 1e-55, Method: Composition-based stats. Identities = 61/290 (21%), Positives = 111/290 (38%), Gaps = 43/290 (15%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 E T +G+G V++G G V +K +D + Sbjct 35 EYTLGEKIGRGAFGQVFKGLNGKTGEF------------------------VAIKQIDSN 70 Query 648 HHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 D + + ++ ++ H ++ V GV + + EYVE+G L + + G Sbjct 71 KIDESSLQSVKGEVEILHKLRHNNIVKVLGVVEVQAQLNFILEYVENGSLRDVI-EKFGP 129 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 + ++ Q+ L+YL + ++H ++ NIL+ + G+ IKL+D GV Sbjct 130 LSEELCIIYLYQMLQGLAYLHSNKVIHRDIKASNILITKEGV-------IKLADFGVASQ 182 Query 766 ALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 S V W+APE + + S+A D W G+T++E+ G P + P Sbjct 183 IDSESQLRFSVVGTPYWMAPESIE--ISGCSSASDIWSLGSTMIELL-TGNPPYYTLQPM 239 Query 822 EKEH--FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + P + Q +PTQRP+ + +L+ Sbjct 240 AAMFRIVSDQHPPFPTDISKEFLDYFQQSFKKDPTQRPTAQELLQHPIFF 289 >sp|Q9S972|SD16_ARATH Receptor-like serine/threonine-protein kinase SD1-6 OS=Arabidopsis thaliana OX=3702 GN=SD16 PE=1 SV=2 Length=847 Score = 248 bits (633), Expect = 2e-67, Method: Composition-based stats. Identities = 73/297 (25%), Positives = 115/297 (39%), Gaps = 21/297 (7%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 LG+G FG V G+ +AVK L Q + Sbjct 511 MEWKALAMATNNFSTDNKLGQGGFGIVYKGML-----LDGKEIAVKRLSK-MSSQGTDEF 564 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQL 1000 E+ ++ L H ++++ GCC D+GEK L+ EY+ SL +L ++ + Sbjct 565 MNEVRLIAKLQHINLVRLLGCCVDKGEK--MLIYEYLENLSLDSHLFDQTRSSNLNWQKR 622 Query 1001 LLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 I G+ YLH IHRDL A NVLLD + KI DFG+A+ Sbjct 623 FDIINGIARGLLYLHQDSRCRIIHRDLKASNVLLDKNMTPKISDFGMARIFGREETEANT 682 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQ 1116 R + +PE + F SDV+SFGV L E+++ + L L+G Sbjct 683 RR-VVGTYGYMSPEYAMDGIFSMKSDVFSFGVLLLEIISGKRNKGFYNSNRDLNLLGFVW 741 Query 1117 GQMTVLRLTELLERGERLPRPDKCPC----EVYHLMKNCWETEASFRPTFENLIPIL 1169 + E+++ + P + C + A RP +++ +L Sbjct 742 RHWKEGKELEIVDPINIDALSSEFPTHEILRCIQIGLLCVQERAEDRPVMSSVMVML 798 Score = 225 bits (574), Expect = 5e-60, Method: Composition-based stats. Identities = 52/274 (19%), Positives = 91/274 (33%), Gaps = 47/274 (17%) Query 566 GARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 L L + + + + + LGQG VY+G L Sbjct 498 SKENKTDYLELPLMEWKALAMATNNFSTDNKLGQGGFGIVYKGMLLDGK----------- 546 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 + +K L F L++++ H +L + G CV E Sbjct 547 --------------EIAVKRLSKMSSQGTDEFMNEVRLIAKLQHINLVRLLGCCVDKGEK 592 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGR 738 +++ EY+E+ LD L + + W + + +A L YL ++H ++ Sbjct 593 MLIYEYLENLSLDSHLFDQTRSSNLNWQKRFDIINGIARGLLYLHQDSRCRIIHRDLKAS 652 Query 739 NILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLS 792 N+LL + + K+SD G+ + V +++PE G S Sbjct 653 NVLLDK-------NMTPKISDFGMARIFGREETEANTRRVVGTYGYMSPEYAMDGI--FS 703 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 D + FG LLEI S + Sbjct 704 MKSDVFSFGVLLLEIISGKRNKGFYNSNRDLNLL 737 >sp|P29376|LTK_HUMAN Leukocyte tyrosine kinase receptor OS=Homo sapiens OX=9606 GN=LTK PE=1 SV=3 Length=864 Score = 248 bits (634), Expect = 2e-67, Method: Composition-based stats. Identities = 89/295 (30%), Positives = 131/295 (44%), Gaps = 34/295 (12%) Query 903 LGEGHFGKVSLYCYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG G FG+V D + VA+K L C PQ + E I+ H++I++ Sbjct 516 LGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVR 575 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--------SIGLAQLLLFAQQICEGMAY 1013 G + + L E + G ++ +L + + LL AQ I +G Y Sbjct 576 CVGLSLRATPRLILL--ELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQLAQDIAQGCHY 633 Query 1014 LHAQHYIHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 L H+IHRD+AARN LL R+ KIGDFG+A+ + YYR + PV W P Sbjct 634 LEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRA-SYYRRGDRALLPVKWMPP 692 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E E F +D WSFGV L+E+ + L + T + + + Sbjct 693 EAFLEGIFTSKTDSWSFGVLLWEIFS--------------LGYMPYPGRTNQEVLDFVVG 738 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 G R+ P CP VY +M CW+ E RP+F +++ L+ Y Q P V + Sbjct 739 GGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQ-----YCTQDPDVLN 788 Score = 248 bits (633), Expect = 2e-67, Method: Composition-based stats. Identities = 84/348 (24%), Positives = 128/348 (37%), Gaps = 51/348 (15%) Query 552 LPQPGETSNLIIMRGARASPRTL----NLSQLSFH-------RVDQKEITQLSHLGQGTR 600 LP P + + R +P L V +T L LG G Sbjct 462 LPSPELELSKLRTSAIRTAPNPYYCQVGLGPAQSWPLPPGVTEVSPANVTLLRALGHGAF 521 Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETA 659 VYEG + G D PL +V +K L L F A Sbjct 522 GEVYEGLV---------IGLPGDSSPL----------QVAIKTLPELCSPQDELDFLMEA 562 Query 660 SLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV----PMAWK--MV 713 ++S+ H ++ G+ +R +++ E + G + +LR R H+ P+ + + Sbjct 563 LIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQ 622 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 +AQ +A YLE + +H ++ RN LL+ G S K+ D G+ Sbjct 623 LAQDIAQGCHYLEENHFIHRDIAARNCLLS----CAGPSRVAKIGDFGMARDIYRASYYR 678 Query 774 ER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 + W+ PE G ++ D W FG L EI G P R+ E F Sbjct 679 RGDRALLPVKWMPPEAFLEGI--FTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFV 736 Query 828 QRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 R+ P CP + + +QC +EP RPSF +IL L Sbjct 737 VGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQYCTQDP 784 >sp|F8W3R9|ALK_DANRE ALK tyrosine kinase receptor OS=Danio rerio OX=7955 GN=alk PE=2 SV=2 Length=1705 Score = 253 bits (647), Expect = 2e-67, Method: Composition-based stats. Identities = 75/340 (22%), Positives = 123/340 (36%), Gaps = 40/340 (12%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 V ++ I+ LG G VYEG L V G+P ++V Sbjct 1104 DLKEVPRRNISLTRGLGHGAFGEVYEG-LAVGIPGEPSP------------------MQV 1144 Query 640 VLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +K L L F A ++S+ SH ++ GV ++ + ++ E + G L + Sbjct 1145 AVKTLPEVCSEQDELDFLMEALIISKFSHQNIVRCIGVSLQALPHFILLELMAGGDLKSF 1204 Query 699 LRRERGH------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752 LR R + M + +A+ +A YLE +H ++ RN LL +G Sbjct 1205 LRETRPRLEHPSSLTMVDLLNIARDIARGCQYLEENQFIHRDIAARNCLLT----CKGPG 1260 Query 753 PFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 K+ D G+ + + W+ PE G ++ D W FG L E Sbjct 1261 RVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPPEAFMEGI--FTSKTDTWSFGVLLWE 1318 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRTILR 864 I G P SRS E F R+ P +CP + + +Q ++P RP+F TIL Sbjct 1319 IFSLGYMPYPSRSNQEVLEFVTNGGRMDPPKNCPGPVYRIMTQSWQHQPEDRPNFSTILE 1378 Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 + + + + + Sbjct 1379 RIDYCLQDPDVVNVPLPVEYGPIPEEEERVPMRPEDPSAP 1418 Score = 249 bits (635), Expect = 6e-66, Method: Composition-based stats. Identities = 90/344 (26%), Positives = 136/344 (40%), Gaps = 34/344 (10%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 Q P + + + + + +D +R + R LG G FG+V Sbjct 1071 QSPDCKLSKLRASTIMTDYNPNYCFGGKTASVNDLKEVPRRNISLTRGLGHGAFGEVYEG 1130 Query 915 CYDPT-NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 + + VAVK L C Q + E I+ H++I++ G Sbjct 1131 LAVGIPGEPSPMQVAVKTLPEVCSEQDELDFLMEALIISKFSHQNIVRCIGVSLQALPHF 1190 Query 974 LQLVMEYVPLGSLRDYLPR--------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 + L E + G L+ +L S+ + LL A+ I G YL +IHRD+A Sbjct 1191 ILL--ELMAGGDLKSFLRETRPRLEHPSSLTMVDLLNIARDIARGCQYLEENQFIHRDIA 1248 Query 1026 ARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082 ARN LL + KIGDFG+A+ + YYR PV W PE E F + Sbjct 1249 ARNCLLTCKGPGRVAKIGDFGMARDIYRA-SYYRKGGRAMLPVKWMPPEAFMEGIFTSKT 1307 Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 D WSFGV L+E+ + L + + + E + G R+ P CP Sbjct 1308 DTWSFGVLLWEIFS--------------LGYMPYPSRSNQEVLEFVTNGGRMDPPKNCPG 1353 Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 VY +M W+ + RP F ++ + Y Q P V +V Sbjct 1354 PVYRIMTQSWQHQPEDRPNFSTILERID-----YCLQDPDVVNV 1392 >sp|O61122|SVKA_DICDI Serine/threonine-protein kinase svkA OS=Dictyostelium discoideum OX=44689 GN=svkA PE=1 SV=1 Length=478 Score = 238 bits (608), Expect = 2e-67, Method: Composition-based stats. Identities = 64/271 (24%), Positives = 116/271 (43%), Gaps = 24/271 (9%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 + +G+G FG+V + N T E +A+K + + +QEI++L Sbjct 12 YVRQEKIGKGSFGEV----FKGINKKTNETIAIKTIDLEDAEDEIEDIQQEINVLSQCES 67 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016 + KY G + L ++MEY+ GS+ D + + + +++ +G+ YLH+ Sbjct 68 PFVTKYFGSFLKGSK--LWIIMEYLAGGSVLDLMKPGPFDEGYIAIILRELLKGLEYLHS 125 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + IHRD+ A NVLL VK+ DFG++ + + R FW APE +K+ Sbjct 126 EGKIHRDIKAANVLLSASGDVKLADFGVSGQLTD---QMTKRNTFVGTPFWMAPEVIKQT 182 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 + +D+WS G+T E+ + PP + + +R L+ + Sbjct 183 GYDSKADIWSMGITALEM-----AKGEPP----------RADLHPMRALFLIPKDPPPTL 227 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 C + + RPT ++L+ Sbjct 228 EGNFSKGFKEFCALCLNKDPNQRPTAKDLLK 258 Score = 200 bits (509), Expect = 4e-54, Method: Composition-based stats. Identities = 55/297 (19%), Positives = 109/297 (37%), Gaps = 44/297 (15%) Query 579 LSFHRVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 ++ + D +E+ + +G+G+ V++G + Sbjct 1 MASKKGDPEELYVRQEKIGKGSFGEVFKGINKKTNE------------------------ 36 Query 638 RVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 + +K +D D + +++SQ + G ++G + ++ EY+ G + Sbjct 37 TIAIKTIDLEDAEDEIEDIQQEINVLSQCESPFVTKYFGSFLKGSKLWIIMEYLAGGSVL 96 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 ++ G + ++ ++L L YL ++ +H ++ N+LL+ S +K Sbjct 97 DLMK--PGPFDEGYIAIILRELLKGLEYLHSEGKIHRDIKAANVLLS-------ASGDVK 147 Query 757 LSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 L+D GV R V W+APE + + D W G T LE+ GE Sbjct 148 LADFGVSGQLTDQMTKRNTFVGTPFWMAPEVIKQ--TGYDSKADIWSMGITALEMA-KGE 204 Query 813 APLQSRSPSEKEHFYQRQ--HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 P P + L + CL +P QRP+ + +L+ Sbjct 205 PPRADLHPMRALFLIPKDPPPTLEGNFSKGFKEFCALCLNKDPNQRPTAKDLLKHKF 261 >sp|Q8VYA3|WAKLJ_ARATH Wall-associated receptor kinase-like 10 OS=Arabidopsis thaliana OX=3702 GN=WAKL10 PE=2 SV=1 Length=769 Score = 246 bits (628), Expect = 2e-67, Method: Composition-based stats. Identities = 74/288 (26%), Positives = 118/288 (41%), Gaps = 19/288 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG G V G +VAVK K + E+ IL + H +I+K Sbjct 439 LGEGGQGTVYKGML-----VDGRIVAVKKSKV-VDEDKLEEFINEVVILSQINHRNIVKL 492 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHA- 1016 GCC + LV E++P G+L ++L S L A I ++YLH+ Sbjct 493 LGCCLETDVP--ILVYEFIPNGNLFEHLHDDSDDYTMTTWEVRLRIAVDIAGALSYLHSA 550 Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 HRD+ + N++LD K+ DFG ++ V H + + V + PE + Sbjct 551 ASSPIYHRDIKSTNIMLDEKHRAKVSDFGTSRTVTVDHTH--LTTVVSGTVGYMDPEYFQ 608 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +F SDV+SFGV L EL+T S S ++ L M RL+++++ R Sbjct 609 SSQFTDKSDVYSFGVVLAELITGEKSVSFLRSQEYRTLATYFTLAMKENRLSDIIDARIR 668 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 + + C + RP+ + L+ + + P Sbjct 669 DGCKLNQVTAAAKIARKCLNMKGRKRPSMRQVSMELEKIRSYSEDMQP 716 Score = 228 bits (581), Expect = 3e-61, Method: Composition-based stats. Identities = 69/409 (17%), Positives = 138/409 (34%), Gaps = 70/409 (17%) Query 505 FPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM 564 + E + ++ G SF ++ +G + ++ + G + Sbjct 349 YTCEYTNHRPLVIGLSTSFSTLVFIGGIYWLYKFIRRQRRLNQKKKFFKRNGGLLLQQQL 408 Query 565 ---RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 G S R N +L + + LG+G + VY+G L Sbjct 409 TTTEGNVDSTRVFNSRELEK---ATENFSLTRILGEGGQGTVYKGMLVDGRI-------- 457 Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 V +K D F ++SQ++H ++ + G C+ Sbjct 458 -----------------VAVKKSKVVDEDKLEEFINEVVILSQINHRNIVKLLGCCLETD 500 Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAW---KMVVAQQLASALSYLE---NKNLVHGNV 735 I+V E++ +G L L + M ++ +A +A ALSYL + + H ++ Sbjct 501 VPILVYEFIPNGNLFEHLHDDSDDYTMTTWEVRLRIAVDIAGALSYLHSAASSPIYHRDI 560 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANS 790 NI+L K+SD G + + ++ PE ++ Sbjct 561 KSTNIMLDEK-------HRAKVSDFGTSRTVTVDHTHLTTVVSGTVGYMDPEYFQ--SSQ 611 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE------HFYQRQHRLPEPSCPQL--- 841 + D + FG L E+ GE + E +++RL + ++ Sbjct 612 FTDKSDVYSFGVVLAELI-TGEKSVSFLRSQEYRTLATYFTLAMKENRLSDIIDARIRDG 670 Query 842 ---------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 A + +CL + +RPS R + +L +++ ++ Sbjct 671 CKLNQVTAAAKIARKCLNMKGRKRPSMRQVSMELEKIRSYSEDMQPYEY 719 >sp|C0LGG7|Y1534_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g53420 OS=Arabidopsis thaliana OX=3702 GN=At1g53420 PE=2 SV=2 Length=953 Score = 249 bits (637), Expect = 2e-67, Method: Composition-based stats. Identities = 73/285 (26%), Positives = 114/285 (40%), Gaps = 19/285 (7%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 +GEG FG V G ++AVK L Q + EI ++ L Sbjct 622 NNFDSANRIGEGGFGPVYKG-----KLFDGTIIAVKQLSTG-SKQGNREFLNEIGMISAL 675 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICE 1009 +H +++K GCC + G+ L LV E+V SL L + + + Sbjct 676 HHPNLVKLYGCCVEGGQ--LLLVYEFVENNSLARALFGPQETQLRLDWPTRRKICIGVAR 733 Query 1010 GMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G+AYLH + +HRD+ A NVLLD KI DFGLAK E + R G Sbjct 734 GLAYLHEESRLKIVHRDIKATNVLLDKQLNPKISDFGLAKLDEEDSTHISTRIAG--TFG 791 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLT 1125 + APE +DV+SFG+ E++ + + LI + L Sbjct 792 YMAPEYAMRGHLTDKADVYSFGIVALEIVHGRSNKIERSKNNTFYLIDWVEVLREKNNLL 851 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 EL++ + + + C +E RP+ ++ +L+ Sbjct 852 ELVDPRLGSEYNREEAMTMIQIAIMCTSSEPCERPSMSEVVKMLE 896 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 67/413 (16%), Positives = 132/413 (32%), Gaps = 70/413 (17%) Query 518 GWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLS 577 G S ++ L L ++ + + + + AS Sbjct 559 RNGMSTGTLHTLVVILSIFIVFLVFGTLWKKGYLRSKSQMEKDFKSLELMIAS------F 612 Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 L ++ + +G+G VY+G+L Sbjct 613 SLRQIKIATNNFDSANRIGEGGFGPVYKGKLFDG-------------------------T 647 Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 + +K L F ++S + H +L ++G CV G + ++V E+VE+ L Sbjct 648 IIAVKQLSTGSKQGNREFLNEIGMISALHHPNLVKLYGCCVEGGQLLLVYEFVENNSLAR 707 Query 698 WLRRERG---HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGT 751 L + + + + +A L+YL + +VH ++ N+LL + Sbjct 708 ALFGPQETQLRLDWPTRRKICIGVARGLAYLHEESRLKIVHRDIKATNVLLDKQLNP--- 764 Query 752 SPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 K+SD G+ + ++APE G L+ D + FG LE Sbjct 765 ----KISDFGLAKLDEEDSTHISTRIAGTFGYMAPEYAMRG--HLTDKADVYSFGIVALE 818 Query 807 ICFDGEAPLQSRSPSEKEHFYQR------QHRLPEPSCPQLAT------------LTSQC 848 I G + RS + + ++ L E P+L + + C Sbjct 819 IV-HGRSNKIERSKNNTFYLIDWVEVLREKNNLLELVDPRLGSEYNREEAMTMIQIAIMC 877 Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901 + EP +RPS +++ L + + + + + Sbjct 878 TSSEPCERPSMSEVVKMLEGKKMVEVEKLEEASVHRETKRLENMNTMKKYYEM 930 >sp|P20806|7LESS_DROVI Protein sevenless OS=Drosophila virilis OX=7244 GN=sev PE=3 SV=1 Length=2594 Score = 254 bits (648), Expect = 2e-67, Method: Composition-based stats. Identities = 90/308 (29%), Positives = 144/308 (47%), Gaps = 41/308 (13%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG G FG+V ++ + VA+K+L+ G + QE ++ HE+I+ Sbjct 2229 FLGSGAFGEVYEGQLQAEDEAQPQRVAIKSLRK--GASEFAELLQEAQLMSNFKHENIVC 2286 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQLLLFAQQICEGMA 1012 G C D S+ L+ME++ G L YL + L +LL + G + Sbjct 2287 LIGICCDTD--SISLIMEHMEAGDLLSYLRAARPSSQEALSKLQLPELLSMCLDVANGCS 2344 Query 1013 YLHAQHYIHRDLAARNVLLDN------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 Y+ H++HRDLA RN L+ + R+VKIGDFGLA+ + + +YYR +G PV Sbjct 2345 YMEDMHFVHRDLACRNCLVSDGAAIGGRRIVKIGDFGLARDIYKS-DYYRKEGEGLLPVR 2403 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W A E L + F SDVW+FGV +E+ T L + Sbjct 2404 WMALESLVDGLFSTQSDVWAFGVLCWEIFT--------------LGQQPYAARNNFEVLA 2449 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ-------GQ 1179 ++ G RL +P++CP ++Y L+ CW +E RP+F+ + L+ + + + Sbjct 2450 HVKEGGRLQQPERCPEKLYALLLQCWRSEPWERPSFKRCLSTLQALSSDLRRTEMLATDE 2509 Query 1180 APSVFSVC 1187 P V ++C Sbjct 2510 TPLVSALC 2517 Score = 252 bits (643), Expect = 9e-67, Method: Composition-based stats. Identities = 86/333 (26%), Positives = 138/333 (41%), Gaps = 48/333 (14%) Query 554 QPGETSNLIIMR------GARASPRTLNLSQLS---FHRVDQKEITQLSHLGQGTRTNVY 604 +P SNL ++ AR+ +++LS +++ +T L LG G VY Sbjct 2180 RPSIWSNLSALQTQQQLLAARSRTFSMSLSDADIALLPQINWNRLTLLRFLGSGAFGEVY 2239 Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664 EG+L+ E D Q RV +K L + A + A LMS Sbjct 2240 EGQLQAE--------------------DEAQPQRVAIKSLRKGASEFA-ELLQEAQLMSN 2278 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-------HVPMAWKMVVAQQ 717 H ++ + G+C ++ E++E G L +LR R + + + + Sbjct 2279 FKHENIVCLIGICCDTDSISLIMEHMEAGDLLSYLRAARPSSQEALSKLQLPELLSMCLD 2338 Query 718 LASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE--- 774 +A+ SY+E+ + VH ++ RN L++ G A G +K+ D G+ + + Sbjct 2339 VANGCSYMEDMHFVHRDLACRNCLVSD-GAAIGGRRIVKIGDFGLARDIYKSDYYRKEGE 2397 Query 775 ---RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 + W+A E L G ST D W FG EI G+ P +R+ E + Sbjct 2398 GLLPVRWMALESLVDGL--FSTQSDVWAFGVLCWEIFTLGQQPYAARNNFEVLAHVKEGG 2455 Query 832 RL--PEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 RL PE +L L QC EP +RPSF+ Sbjct 2456 RLQQPERCPEKLYALLLQCWRSEPWERPSFKRC 2488 >sp|F4HRJ4|M3K3A_ARATH Mitogen-activated protein kinase kinase kinase 3 OS=Arabidopsis thaliana OX=3702 GN=MAPKKK3 PE=1 SV=1 Length=609 Score = 242 bits (618), Expect = 2e-67, Method: Composition-based stats. Identities = 80/334 (24%), Positives = 137/334 (41%), Gaps = 32/334 (10%) Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919 + + + + KK + LG G FG+V L Sbjct 177 SECHPLPRPPTSPTSPSAVHGSRIGGGYETSPSGFSTWKKGKFLGSGTFGQVYLGF---- 232 Query 920 NDGTGEMVAVKALKADCGPQHRSG----WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 N G+M A+K +K Q QEI++L L H +I++Y G + E++L Sbjct 233 NSEKGKMCAIKEVKVISDDQTSKECLKQLNQEINLLNQLCHPNIVQYYGS--ELSEETLS 290 Query 976 LVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND 1034 + +EYV GS+ L + S + + +QI G+AYLH ++ +HRD+ N+L+D + Sbjct 291 VYLEYVSGGSIHKLLKDYGSFTEPVIQNYTRQILAGLAYLHGRNTVHRDIKGANILVDPN 350 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK-EYKFYYASDVWSFGVTLYE 1093 +K+ DFG+AK V + +W APE + + + +A D+WS G T+ E Sbjct 351 GEIKLADFGMAKHV----TAFSTMLSFKGSPYWMAPEVVMSQNGYTHAVDIWSLGCTILE 406 Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 + T PP E + + ++ + PD + + ++ C + Sbjct 407 MAT-----SKPPWSQFEGVA---------AIFKIGNSKDTPEIPDHLSNDAKNFIRLCLQ 452 Query 1154 TEASFRPTFENLI--PILKTVHEKYQGQAPSVFS 1185 + RPT L+ P L+ P F Sbjct 453 RNPTVRPTASQLLEHPFLRNTTRVASTSLPKDFP 486 Score = 192 bits (488), Expect = 2e-50, Method: Composition-based stats. Identities = 58/284 (20%), Positives = 99/284 (35%), Gaps = 35/284 (12%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 + LG GT VY G +G + V + D + Sbjct 215 KKGKFLGSGTFGQVYLGFNSEKGKMCAIK-------------------EVKVISDDQTSK 255 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 + + +L++Q+ H ++ +G + + EYV G + L+ G Sbjct 256 ECLKQLNQEINLLNQLCHPNIVQYYGSELSEETLSVYLEYVSGGSIHKLLKD-YGSFTEP 314 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 +Q+ + L+YL +N VH ++ G NIL+ G IKL+D G+ + Sbjct 315 VIQNYTRQILAGLAYLHGRNTVHRDIKGANILVDPNGE-------IKLADFGMAKHVTAF 367 Query 770 EERV---ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + W+APE + N + A+D W G T+LE+ + P Sbjct 368 STMLSFKGSPYWMAPEVVMS-QNGYTHAVDIWSLGCTILEMATS-KPPWSQFEGVAAIFK 425 Query 827 YQRQH---RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 +P+ CL PT RP+ +L Sbjct 426 IGNSKDTPEIPDHLSNDAKNFIRLCLQRNPTVRPTASQLLEHPF 469 >sp|Q00993|UFO_MOUSE Tyrosine-protein kinase receptor UFO OS=Mus musculus OX=10090 GN=Axl PE=1 SV=2 Length=888 Score = 248 bits (634), Expect = 2e-67, Method: Composition-based stats. Identities = 84/282 (30%), Positives = 126/282 (45%), Gaps = 29/282 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHII 960 LGEG FG V + D + VAVK +K A C + E ++ H +++ Sbjct 535 TLGEGEFGAVMEGQLN--QDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVM 592 Query 961 KYKGCCEDQGEKS----LQLVMEYVPLGSLRDYLPRHSIGLA-------QLLLFAQQICE 1009 + G C ++ +++ ++ G L +L +G L+ F I Sbjct 593 RLIGVCFQGSDREGFPEPVVILPFMKHGDLHSFLLYSRLGDQPVFLPTQMLVKFMADIAS 652 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 GM YL + +IHRDLAARN +L+ + V + DFGL+K + G +YYR PV W A Sbjct 653 GMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNG-DYYRQGRIAKMPVKWIA 711 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E L + + SDVWSFGVT++E+ T + + + L Sbjct 712 IESLADRVYTSKSDVWSFGVTMWEIATRGQ--------------TPYPGVENSEIYDYLR 757 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +G RL +P C +Y LM CWE RP+F L L+ Sbjct 758 QGNRLKQPVDCLDGLYALMSRCWELNPRDRPSFAELREDLEN 799 Score = 224 bits (571), Expect = 2e-59, Method: Composition-based stats. Identities = 68/307 (22%), Positives = 117/307 (38%), Gaps = 52/307 (17%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 +L VD+ ++ LG+G V EG+L + S L Sbjct 519 KLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSI----------------------L 556 Query 638 RVVLKVLDP--SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEY 689 +V +K + F A M + H ++ + GVC +G PE +++ + Sbjct 557 KVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSDREGFPEPVVILPF 616 Query 690 VEHGPLDVWLRRERG-----HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 ++HG L +L R +P + +AS + YL K +H ++ RN +L Sbjct 617 MKHGDLHSFLLYSRLGDQPVFLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNE 676 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKW 798 + + ++D G+ + + + W+A E L ++ D W Sbjct 677 -------NMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRV--YTSKSDVW 727 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 FG T+ EI G+ P SE + ++ +RL P L L S+C P R Sbjct 728 SFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPVDCLDGLYALMSRCWELNPRDR 787 Query 857 PSFRTIL 863 PSF + Sbjct 788 PSFAELR 794 >sp|P55146|TYRO3_RAT Tyrosine-protein kinase receptor TYRO3 OS=Rattus norvegicus OX=10116 GN=Tyro3 PE=1 SV=1 Length=880 Score = 248 bits (633), Expect = 2e-67, Method: Composition-based stats. Identities = 87/282 (31%), Positives = 130/282 (46%), Gaps = 28/282 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 LG+G FG V DG+ VAVK LKAD + +E ++ H H+ K Sbjct 514 LGKGEFGSVREAQLK-QEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAK 572 Query 962 YKGCCED---QGEKSL-QLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEG 1010 G +G + +++ ++ G L +L ++ L L+ F I G Sbjct 573 LVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLVRFMVDIACG 632 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 M YL ++++IHRDLAARN +L D V + DFGL++ + G +YYR PV W A Sbjct 633 MEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSG-DYYRQGCASKLPVKWLAL 691 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E L + + SDVW+FGVT++E++T + + L Sbjct 692 ESLADNLYTVHSDVWAFGVTMWEIMTRGQ--------------TPYAGIENAEIYNYLIS 737 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 G RL +P +C EVY LM CW + RP+F L L+ + Sbjct 738 GNRLKQPPECMEEVYDLMYQCWSADPKQRPSFTCLRMELENI 779 Score = 234 bits (597), Expect = 9e-63, Method: Composition-based stats. Identities = 70/316 (22%), Positives = 128/316 (41%), Gaps = 51/316 (16%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 +L + +++ T LG+G +V E +L+ E G + Sbjct 497 KLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQED---------------------GSFV 535 Query 638 RVVLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEY 689 +V +K+L F A+ M + H H+A + GV +R P +++ + Sbjct 536 KVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF 595 Query 690 VEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 ++HG L +L R ++P+ + +A + YL ++N +H ++ RN +LA Sbjct 596 MKHGDLHAFLLASRIGENPFNLPLQTLVRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE 655 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKW 798 + ++D G+ S + + + WLA E L + D W Sbjct 656 -------DMTVCVADFGLSRKIYSGDYYRQGCASKLPVKWLALESLADNL--YTVHSDVW 706 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 FG T+ EI G+ P +E ++ +RL P ++ L QC + +P QR Sbjct 707 AFGVTMWEIMTRGQTPYAGIENAEIYNYLISGNRLKQPPECMEEVYDLMYQCWSADPKQR 766 Query 857 PSFRTILRDLTRLQPH 872 PSF + +L + H Sbjct 767 PSFTCLRMELENILGH 782 >sp|Q9SXB4|Y1130_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g11300 OS=Arabidopsis thaliana OX=3702 GN=At1g11300 PE=2 SV=1 Length=820 Score = 247 bits (630), Expect = 2e-67, Method: Composition-based stats. Identities = 79/294 (27%), Positives = 122/294 (41%), Gaps = 23/294 (8%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG V G+ +AVK L G Q E+ ++ L H ++ Sbjct 512 RNKLGQGGFGPVYKGKLQE-----GQEIAVKRLSRASG-QGLEELVNEVVVISKLQHRNL 565 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLH 1015 +K GCC E+ LV E++P SL YL + IC G+ YLH Sbjct 566 VKLLGCCIAGEER--MLVYEFMPKKSLDYYLFDSRRAKLLDWKTRFNIINGICRGLLYLH 623 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 IHRDL A N+LLD + + KI DFGLA+ P + R + APE Sbjct 624 RDSRLRIIHRDLKASNILLDENLIPKISDFGLARIFPGNEDEANTRR-VVGTYGYMAPEY 682 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 F SDV+S GV L E+++ +S S L+ + L++ Sbjct 683 AMGGLFSEKSDVFSLGVILLEIISGRRNSNST------LLAYVWSIWNEGEINSLVDPEI 736 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT-VHEKYQGQAPSVFS 1185 +K + H+ C + A+ RP+ + +L + + + + + P+ S Sbjct 737 FDLLFEKEIHKCIHIGLLCVQEAANDRPSVSTVCSMLSSEIADIPEPKQPAFIS 790 Score = 235 bits (600), Expect = 2e-63, Method: Composition-based stats. Identities = 63/326 (19%), Positives = 109/326 (33%), Gaps = 53/326 (16%) Query 501 RLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGE--- 557 RL I+ +D +L G + + C+L A R + E Sbjct 423 RLAHSEIKTKDKRPILIGT-----ILAGGIFVVAACVLLARRIVMKKRAKKKGRDAEQIF 477 Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 + G + + L L + + + LGQG VY+G+L+ Sbjct 478 ERVEALAGGNKGKLKELPLFEFQVLAAATNNFSLRNKLGQGGFGPVYKGKLQEGQ----- 532 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 + +K L + ++S++ H +L + G C Sbjct 533 --------------------EIAVKRLSRASGQGLEELVNEVVVISKLQHRNLVKLLGCC 572 Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVH 732 + G E ++V E++ LD +L R + W + + + L YL ++H Sbjct 573 IAGEERMLVYEFMPKKSLDYYLFDSRRAKLLDWKTRFNIINGICRGLLYLHRDSRLRIIH 632 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPG 786 ++ NILL + K+SD G+ + V ++APE G Sbjct 633 RDLKASNILLDE-------NLIPKISDFGLARIFPGNEDEANTRRVVGTYGYMAPEYAMG 685 Query 787 GANSLSTAMDKWGFGATLLEICFDGE 812 G S D + G LLEI Sbjct 686 GL--FSEKSDVFSLGVILLEIISGRR 709 >sp|Q8L710|CRK17_ARATH Cysteine-rich receptor-like protein kinase 17 OS=Arabidopsis thaliana OX=3702 GN=CRK17 PE=2 SV=2 Length=686 Score = 244 bits (623), Expect = 2e-67, Method: Composition-based stats. Identities = 74/281 (26%), Positives = 112/281 (40%), Gaps = 18/281 (6%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG G FG+V G +AVK L G Q +K E+ ++ L H ++ Sbjct 362 HNKLGAGGFGEVYKGML-----LNGTEIAVKRLSKTSG-QGEIEFKNEVVVVAKLQHINL 415 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015 ++ G EK LV E+VP SL +L R+ + I G+ YLH Sbjct 416 VRLLGFSLQGEEK--LLVYEFVPNKSLDYFLFDPNKRNQLDWTVRRNIIGGITRGILYLH 473 Query 1016 ---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 IHRDL A N+LLD D KI DFG+A+ + +PE Sbjct 474 QDSRLKIIHRDLKASNILLDADMNPKIADFGMARIFGVDQTVANTAR-VVGTFGYMSPEY 532 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL--ELIGIAQGQMTVLRLTELLER 1130 + +F SDV+SFGV + E+++ +S L L+ + EL++ Sbjct 533 VTHGQFSMKSDVYSFGVLILEIISGKKNSSFYQMDGLVNNLVTYVWKLWENKTMHELIDP 592 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + H+ C + + RPT + +L T Sbjct 593 FIKEDCKSDEVIRYVHIGLLCVQENPADRPTMSTIHQVLTT 633 Score = 228 bits (580), Expect = 9e-62, Method: Composition-based stats. Identities = 70/483 (14%), Positives = 143/483 (30%), Gaps = 93/483 (19%) Query 433 YLCHEVAPPRLVMSIR-----------DGIHGPLLEPFVQAKLRP----EDGLYLIHWST 477 Y +VAP + +I + L + + G ++ S Sbjct 189 YYAKDVAPEPVYGNISVVMQCTPDVSSKDCN--LCLERSLDFYKKWYNGKRGTIILRPSC 246 Query 478 SHPYRLILTVAQRSQAPDGMQSLRLRKF-------PIEQQDGAFVLEGWGRSFPSVRELG 530 +R L + + + S S + Sbjct 247 --FFRWELYTFFGAFDSINARHPPPPPRPLSPPPLKTPSVTNQTNITKKNDSRISGGTIA 304 Query 531 AALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEIT 590 A + ++ L C + + L I+ S + L + Sbjct 305 AIVVVVVVTIILIVVGLVICKRRKQKQEIELPIVLNEAESVQ----FDLKTIEAATGNFS 360 Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + + LG G VY+G L + +K L + Sbjct 361 EHNKLGAGGFGEVYKGMLLNG-------------------------TEIAVKRLSKTSGQ 395 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--RERGHVPM 708 + F +++++ H +L + G ++G E ++V E+V + LD +L +R + Sbjct 396 GEIEFKNEVVVVAKLQHINLVRLLGFSLQGEEKLLVYEFVPNKSLDYFLFDPNKRNQLDW 455 Query 709 AWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL- 764 + + + + YL ++H ++ NILL K++D G+ Sbjct 456 TVRRNIIGGITRGILYLHQDSRLKIIHRDLKASNILLD-------ADMNPKIADFGMARI 508 Query 765 -----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE----APL 815 + V +++PE + G S D + FG +LEI + + Sbjct 509 FGVDQTVANTARVVGTFGYMSPEYVTHG--QFSMKSDVYSFGVLILEIISGKKNSSFYQM 566 Query 816 QSRSPSEKEHFY--QRQHRLPEPSCPQLAT------------LTSQCLTYEPTQRPSFRT 861 + + + + E P + + C+ P RP+ T Sbjct 567 DGLVNNLVTYVWKLWENKTMHELIDPFIKEDCKSDEVIRYVHIGLLCVQENPADRPTMST 626 Query 862 ILR 864 I + Sbjct 627 IHQ 629 >sp|C0LGF4|FEI1_ARATH LRR receptor-like serine/threonine-protein kinase FEI 1 OS=Arabidopsis thaliana OX=3702 GN=FEI1 PE=1 SV=1 Length=591 Score = 241 bits (616), Expect = 2e-67, Method: Composition-based stats. Identities = 66/313 (21%), Positives = 136/313 (43%), Gaps = 20/313 (6%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + +S + L + +G G FG V D G++ A+K + Sbjct 287 MFHGDLPYSSKDIIKKLEMLNEEHIIGCGGFGTVYKLAMD-----DGKVFALKRI-LKLN 340 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995 +++E++IL ++ H +++ +G C K L+ +Y+P GSL + L + Sbjct 341 EGFDRFFERELEILGSIKHRYLVNLRGYCNSPTSK--LLLYDYLPGGSLDEALHERGEQL 398 Query 996 GLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 + +G++YLH + IHRD+ + N+LLD + ++ DFGLAK + + Sbjct 399 DWDSRVNIIIGAAKGLSYLHHDCSPRIIHRDIKSSNILLDGNLEARVSDFGLAKLLEDEE 458 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP-TKFLEL 1111 + + + APE ++ + +DV+SFGV + E+L+ + + K L + Sbjct 459 SH--ITTIVAGTFGYLAPEYMQSGRATEKTDVYSFGVLVLEVLSGKRPTDASFIEKGLNV 516 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +G + ++ R ++++ + + + + C RPT ++ +L++ Sbjct 517 VGWLKFLISEKRPRDIVDPNCEGMQ-MESLDALLSIATQCVSPSPEERPTMHRVVQLLES 575 Query 1172 VHEKYQGQAPSVF 1184 + PS F Sbjct 576 ---EVMTPCPSEF 585 Score = 192 bits (488), Expect = 2e-50, Method: Composition-based stats. Identities = 63/397 (16%), Positives = 126/397 (32%), Gaps = 68/397 (17%) Query 508 EQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGA 567 ++ G ++ + GC L ++ G S +++ G Sbjct 233 KKNSGKLLISASATVGALLLVALMCFWGCFLYKKLGKVEIKSLAKDVGGGAS-IVMFHGD 291 Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 + +L + + + +G G VY+ MDD Sbjct 292 LPYSSKDIIKKL-------EMLNEEHIIGCGGFGTVYK-------------LAMDDGKVF 331 Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 LK + + F ++ + H +L + G C +++ Sbjct 332 ------------ALKRILKLNEGFDRFFERELEILGSIKHRYLVNLRGYCNSPTSKLLLY 379 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLAR 744 +Y+ G LD L + ++ + A LSYL + ++H ++ NILL Sbjct 380 DYLPGGSLDEALHERGEQLDWDSRVNIIIGAAKGLSYLHHDCSPRIIHRDIKSSNILLD- 438 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWG 799 + ++SD G+ E + +LAPE + G + D + Sbjct 439 ------GNLEARVSDFGLAKLLEDEESHITTIVAGTFGYLAPEYMQSGRA--TEKTDVYS 490 Query 800 FGATLLEICFDGEAPLQ------SRSPSEKEHFYQRQHRLPEPSCPQ-----------LA 842 FG +LE+ G+ P + F + R + P L Sbjct 491 FGVLVLEVLS-GKRPTDASFIEKGLNVVGWLKFLISEKRPRDIVDPNCEGMQMESLDALL 549 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 ++ +QC++ P +RP+ +++ L Sbjct 550 SIATQCVSPSPEERPTMHRVVQLLESEVMTPCPSEFY 586 >sp|C0LGG9|Y5344_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g53440 OS=Arabidopsis thaliana OX=3702 GN=At1g53440 PE=2 SV=2 Length=1035 Score = 250 bits (639), Expect = 2e-67, Method: Composition-based stats. Identities = 78/285 (27%), Positives = 122/285 (43%), Gaps = 19/285 (7%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 +GEG FG V G +AVK L + Q + EI ++ L Sbjct 665 NNFDPENKIGEGGFGPVYKGVL-----ADGMTIAVKQLSSK-SKQGNREFVTEIGMISAL 718 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICE 1009 H +++K GCC + E L LV EY+ SL L R + + I + Sbjct 719 QHPNLVKLYGCCIEGKE--LLLVYEYLENNSLARALFGTEKQRLHLDWSTRNKVCIGIAK 776 Query 1010 GMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 G+AYLH + +HRD+ A NVLLD KI DFGLAK E + + R G + Sbjct 777 GLAYLHEESRLKIVHRDIKATNVLLDLSLNAKISDFGLAKLDEEENTHISTRIAG--TIG 834 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHC-DSSQSPPTKFLELIGIAQGQMTVLRLT 1125 + APE +DV+SFGV E+++ +++ P +F+ L+ A L Sbjct 835 YMAPEYAMRGYLTDKADVYSFGVVCLEIVSGKSNTNYRPKEEFIYLLDWAYVLQEQGSLL 894 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 EL++ K + ++ C + RP +++ +L+ Sbjct 895 ELVDPDLGTSFSKKEAMRMLNIALLCTNPSPTLRPPMSSVVSMLQ 939 Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats. Identities = 71/366 (19%), Positives = 123/366 (34%), Gaps = 70/366 (19%) Query 529 LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKE 588 + AA L LR E +RG + L Q+ + Sbjct 613 VIAACVAFGLLV---LVILRLTGYLGGKEVDENEELRGLDLQTGSFTLKQI---KRATNN 666 Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 + +G+G VY+G L + + +K L Sbjct 667 FDPENKIGEGGFGPVYKGVLADG-------------------------MTIAVKQLSSKS 701 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR---RERGH 705 F ++S + H +L ++G C+ G E ++V EY+E+ L L ++R H Sbjct 702 KQGNREFVTEIGMISALQHPNLVKLYGCCIEGKELLLVYEYLENNSLARALFGTEKQRLH 761 Query 706 VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + + + V +A L+YL + +VH ++ N+LL S K+SD G+ Sbjct 762 LDWSTRNKVCIGIAKGLAYLHEESRLKIVHRDIKATNVLLD-------LSLNAKISDFGL 814 Query 763 GLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + I ++APE G L+ D + FG LEI G++ Sbjct 815 AKLDEEENTHISTRIAGTIGYMAPEYAMRGY--LTDKADVYSFGVVCLEIVS-GKSNTNY 871 Query 818 RSPSEKEHFYQRQHRLPEPSC------------------PQLATLTSQCLTYEPTQRPSF 859 R E + + L E ++ + C PT RP Sbjct 872 RPKEEFIYLLDWAYVLQEQGSLLELVDPDLGTSFSKKEAMRMLNIALLCTNPSPTLRPPM 931 Query 860 RTILRD 865 +++ Sbjct 932 SSVVSM 937 >sp|Q86IX1|DST1_DICDI Serine/threonine-protein kinase dst1 OS=Dictyostelium discoideum OX=44689 GN=dst1 PE=3 SV=1 Length=737 Score = 245 bits (625), Expect = 3e-67, Method: Composition-based stats. Identities = 73/295 (25%), Positives = 127/295 (43%), Gaps = 33/295 (11%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + LG+G FG+V + + G++VA+K + D + ++EI Sbjct 22 PDDPQTIYHIQERLGKGSFGQV----FKAVHFANGKVVAIKIISLD-DQEAIKDVRKEIS 76 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQIC 1008 IL + +I++Y G + L +VMEY GS+ D L +I ++ L ++ Sbjct 77 ILAECNYPNIVQYFGSYFK--DHQLWIVMEYCGGGSVSDLLQVIDTISEDEIALICREAL 134 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +G+ YLH IHRD+ N+LL++ VK+ DFG++ + + R +W Sbjct 135 KGLNYLHEFKKIHRDIKGGNILLNDRGEVKLADFGVSAQLF---NTFSKRNTFVGTPYWM 191 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 APE ++E K+ +DVWS G+T E+ + +R+ ++ Sbjct 192 APEVIQENKYDGKADVWSLGITAIEMAEGLPP---------------NSNVHPMRVIFMI 236 Query 1129 ERGERLPRPDK--CPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 R E DK + + C + + RPT + L+ HE Q + P Sbjct 237 PREESPALTDKSIWSDKFQDFISKCLTKDPAERPTAKELLN-----HEFIQTKKP 286 Score = 202 bits (514), Expect = 7e-53, Method: Composition-based stats. Identities = 53/283 (19%), Positives = 101/283 (36%), Gaps = 43/283 (15%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 LG+G+ V++ G V +K++ + Sbjct 33 ERLGKGSFGQVFKAVHFANGK------------------------VVAIKIISLDDQEAI 68 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 + S++++ ++ ++ G + + +V EY G + L+ + Sbjct 69 KDVRKEISILAECNYPNIVQYFGSYFKDHQLWIVMEYCGGGSVSDLLQVID-TISEDEIA 127 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS---- 768 ++ ++ L+YL +H ++ G NILL G +KL+D GV + Sbjct 128 LICREALKGLNYLHEFKKIHRDIKGGNILLNDRGE-------VKLADFGVSAQLFNTFSK 180 Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 R V W+APE + N D W G T +E+ +G P + P Sbjct 181 RNTFVGTPYWMAPEVIQE--NKYDGKADVWSLGITAIEMA-EGLPPNSNVHPMRVIFMIP 237 Query 829 RQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 R+ + S+CLT +P +RP+ + +L Sbjct 238 REESPALTDKSIWSDKFQDFISKCLTKDPAERPTAKELLNHEF 280 >sp|O23082|CRK44_ARATH Cysteine-rich receptor-like protein kinase 44 OS=Arabidopsis thaliana OX=3702 GN=CRK44 PE=3 SV=2 Length=379 Score = 235 bits (599), Expect = 3e-67, Method: Composition-based stats. Identities = 69/282 (24%), Positives = 115/282 (41%), Gaps = 18/282 (6%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 LGEG FG V D +GE +AVK L G Q + + E+ ++ L H + Sbjct 58 PYNHLGEGGFGAVYKGVLD-----SGEEIAVKRLSMKSG-QGDNEFVNEVSLVAKLQHRN 111 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYL 1014 +++ G C E+ L+ E+ SL ++ R + + + G+ YL Sbjct 112 LVRLLGFCFKGEER--LLIYEFFKNTSLEKFIFDSDRRMILDWEKRYRIISGVARGLLYL 169 Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV-REDGDSPVFWYAP 1070 H IHRD+ A NVLLD+ KI DFG+ K + + AP Sbjct 170 HEDSHFKIIHRDMKASNVLLDDAMNPKIADFGMVKLFNTDQTSQTMFTSKVAGTYGYMAP 229 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQMTVLRLTELLE 1129 E +F +DV+SFGV + E++ ++ SP + L L+ + +++ Sbjct 230 EYAMSGQFSVKTDVFSFGVLVLEIIKGKKNNWSPEEQSSLFLLSYVWKCWREGEVLNIVD 289 Query 1130 RGERLPR-PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 R + H+ C + RPT +++ +L Sbjct 290 PSLIETRGLSDEIRKCIHIGLLCVQENPGSRPTMASIVRMLN 331 Score = 219 bits (559), Expect = 6e-62, Method: Composition-based stats. Identities = 60/322 (19%), Positives = 115/322 (36%), Gaps = 71/322 (22%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 R+ + + +HLG+G VY+G L D G+E Sbjct 45 DFDTIRLATNDFSPYNHLGEGGFGAVYKGVL-----------------------DSGEE- 80 Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 + +K L F SL++++ H +L + G C +G E +++ E+ ++ L+ Sbjct 81 -IAVKRLSMKSGQGDNEFVNEVSLVAKLQHRNLVRLLGFCFKGEERLLIYEFFKNTSLEK 139 Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752 ++ + + W + + +A L YL ++H ++ N+LL + Sbjct 140 FIFDSDRRMILDWEKRYRIISGVARGLLYLHEDSHFKIIHRDMKASNVLLD-------DA 192 Query 753 PFIKLSDPGV--------GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 K++D G+ + + ++APE G S D + FG + Sbjct 193 MNPKIADFGMVKLFNTDQTSQTMFTSKVAGTYGYMAPEYAMSG--QFSVKTDVFSFGVLV 250 Query 805 LEICFDGEAPLQSRSPSEKEHF--------YQRQHRLPEPSCPQLAT------------- 843 LEI + + SP E+ R+ + P L Sbjct 251 LEIIKGKK---NNWSPEEQSSLFLLSYVWKCWREGEVLNIVDPSLIETRGLSDEIRKCIH 307 Query 844 LTSQCLTYEPTQRPSFRTILRD 865 + C+ P RP+ +I+R Sbjct 308 IGLLCVQENPGSRPTMASIVRM 329 >sp|O64793|Y1675_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g67520 OS=Arabidopsis thaliana OX=3702 GN=At1g67520 PE=2 SV=3 Length=818 Score = 247 bits (630), Expect = 3e-67, Method: Composition-based stats. Identities = 77/281 (27%), Positives = 120/281 (43%), Gaps = 23/281 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LGEG FG V GE VA+K L G Q +K E ++ L H +++ Sbjct 500 NKLGEGGFGPVYKG-----KLLNGEEVAIKRLSLASG-QGLVEFKNEAILIAKLQHTNLV 553 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSL----RDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016 + GCC ++ EK L+ EY+ SL D L ++ + + I +G+ YLH Sbjct 554 QVLGCCIEKDEK--MLIYEYMQNKSLDYFLFDPLRKNVLDWTLRFRIMEGIIQGLLYLHK 611 Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRD+ A N+LLD D KI DFGLA+ + + +PE Sbjct 612 YSRLKVIHRDIKASNILLDEDMNPKISDFGLARIFGAEETRANTKRVA-GTFGYMSPEYF 670 Query 1074 KEYKFYYASDVWSFGVTLYELLTHC--DSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 +E F SDV+SFGV + E++ +S L LI ++ E+++ Sbjct 671 REGLFSAKSDVFSFGVLMLEIICGRKNNSFHHDLEGPLNLIVHVWNLFKENKIREVIDLS 730 Query 1132 ER---LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 R L P + C + A RP+ +++ ++ Sbjct 731 LRDSALDYPQ--VLRCVQVALLCVQENAEDRPSMLDVVSMI 769 Score = 227 bits (579), Expect = 1e-60, Method: Composition-based stats. Identities = 52/280 (19%), Positives = 96/280 (34%), Gaps = 45/280 (16%) Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 R R S L + + + + LG+G VY+G+L Sbjct 472 RNERKSNNELQIFSFESVVSATDDFSDENKLGEGGFGPVYKGKLLNGE------------ 519 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 V +K L + + F A L++++ HT+L V G C+ E + Sbjct 520 -------------EVAIKRLSLASGQGLVEFKNEAILIAKLQHTNLVQVLGCCIEKDEKM 566 Query 685 MVTEYVEHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRN 739 ++ EY+++ LD +L + + + + + + L YL ++H ++ N Sbjct 567 LIYEYMQNKSLDYFLFDPLRKNVLDWTLRFRIMEGIIQGLLYLHKYSRLKVIHRDIKASN 626 Query 740 ILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLST 793 ILL K+SD G+ + + +++PE G S Sbjct 627 ILLDE-------DMNPKISDFGLARIFGAEETRANTKRVAGTFGYMSPEYFREGL--FSA 677 Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833 D + FG +LEI + + L Sbjct 678 KSDVFSFGVLMLEIICGRKNNSFHHDLEGPLNLIVHVWNL 717 >sp|Q9LDN1|CRK33_ARATH Putative cysteine-rich receptor-like protein kinase 33 OS=Arabidopsis thaliana OX=3702 GN=CRK33 PE=3 SV=1 Length=636 Score = 243 bits (619), Expect = 3e-67, Method: Composition-based stats. Identities = 71/286 (25%), Positives = 112/286 (39%), Gaps = 18/286 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 K LG+G FG+V G +AVK L + Q ++ E ++ L Sbjct 319 CTFSKCNMLGQGGFGEVFKGVLQ-----DGSEIAVKRLSKE-SAQGVQEFQNETSLVAKL 372 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEG 1010 H +++ G C + EK LV E+VP SL +L + + A+ G Sbjct 373 QHRNLVGVLGFCMEGEEK--ILVYEFVPNKSLDQFLFEPTKKGQLDWAKRYKIIVGTARG 430 Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH IHRDL A N+LLD + K+ DFG+A+ R + Sbjct 431 ILYLHHDSPLKIIHRDLKASNILLDAEMEPKVADFGMARIFRVDQSRADTRR-VVGTHGY 489 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLT 1125 +PE L +F SDV+SFGV + E+++ + L+ A Sbjct 490 ISPEYLMHGQFSVKSDVYSFGVLVLEIISGKRNSNFHETDESGKNLVTYAWRHWRNGSPL 549 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 EL++ H+ C + + RP +I +L + Sbjct 550 ELVDSELEKNYQSNEVFRCIHIALLCVQNDPEQRPNLSTIIMMLTS 595 Score = 227 bits (579), Expect = 6e-62, Method: Composition-based stats. Identities = 63/326 (19%), Positives = 110/326 (34%), Gaps = 63/326 (19%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 SP+ L ++ + LGQG V++G L+ Sbjct 301 ESPKYSLQYDLKTIEAATCTFSKCNMLGQGGFGEVFKGVLQDGS---------------- 344 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 + +K L F SL++++ H +L V G C+ G E I+V E Sbjct 345 ---------EIAVKRLSKESAQGVQEFQNETSLVAKLQHRNLVGVLGFCMEGEEKILVYE 395 Query 689 YVEHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLA 743 +V + LD +L ++G + A + + A + YL + ++H ++ NILL Sbjct 396 FVPNKSLDQFLFEPTKKGQLDWAKRYKIIVGTARGILYLHHDSPLKIIHRDLKASNILLD 455 Query 744 RLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDK 797 K++D G+ V +++PE L G S D Sbjct 456 AEMEP-------KVADFGMARIFRVDQSRADTRRVVGTHGYISPEYLMHG--QFSVKSDV 506 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------------ 839 + FG +LEI + ++ R P Sbjct 507 YSFGVLVLEIISGKRNSNFHETDESGKNLVTYAWRHWRNGSPLELVDSELEKNYQSNEVF 566 Query 840 QLATLTSQCLTYEPTQRPSFRTILRD 865 + + C+ +P QRP+ TI+ Sbjct 567 RCIHIALLCVQNDPEQRPNLSTIIMM 592 >sp|Q9C5S9|CRK6_ARATH Cysteine-rich receptor-like protein kinase 6 OS=Arabidopsis thaliana OX=3702 GN=CRK6 PE=1 SV=1 Length=674 Score = 243 bits (621), Expect = 3e-67, Method: Composition-based stats. Identities = 74/279 (27%), Positives = 119/279 (43%), Gaps = 17/279 (6%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G FG+V + G+ VAVK L + Q + +K E+ ++ L H +++ Sbjct 355 NKIGRGGFGEVYKGTF-----SNGKEVAVKRLSKN-SRQGEAEFKTEVVVVAKLQHRNLV 408 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016 + G QGE+ + LV EY+P SL L + + Q I G+ YLH Sbjct 409 RLLG-FSLQGEERI-LVYEYMPNKSLDCLLFDPTKQIQLDWMQRYNIIGGIARGILYLHQ 466 Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRDL A N+LLD D KI DFG+A+ + APE Sbjct 467 DSRLTIIHRDLKASNILLDADINPKIADFGMARIFGLDQTQDNTSR-IVGTYGYMAPEYA 525 Query 1074 KEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 +F SDV+SFGV + E+++ +SS +L+ A T + +L++ Sbjct 526 MHGQFSMKSDVYSFGVLVLEIISGRKNSSFGESDGAQDLLTHAWRLWTNKKALDLVDPLI 585 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + H+ C + + + RP + +L + Sbjct 586 AENCQNSEVVRCIHIGLLCVQEDPAKRPAISTVFMMLTS 624 Score = 231 bits (590), Expect = 4e-63, Method: Composition-based stats. Identities = 59/358 (16%), Positives = 112/358 (31%), Gaps = 66/358 (18%) Query 578 QLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 QL + + + + + +G+G VY+G Sbjct 338 QLDYRTIQTATNDFAESNKIGRGGFGEVYKGTFSNGK----------------------- 374 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K L + F +++++ H +L + G ++G E I+V EY+ + L Sbjct 375 --EVAVKRLSKNSRQGEAEFKTEVVVVAKLQHRNLVRLLGFSLQGEERILVYEYMPNKSL 432 Query 696 DVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEG 750 D L + + W + + +A + YL + ++H ++ NILL Sbjct 433 DCLLFDPTKQIQLDWMQRYNIIGGIARGILYLHQDSRLTIIHRDLKASNILLD------- 485 Query 751 TSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 K++D G+ + V ++APE G S D + FG + Sbjct 486 ADINPKIADFGMARIFGLDQTQDNTSRIVGTYGYMAPEYAMHG--QFSMKSDVYSFGVLV 543 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLP------EPSCPQLAT------------LTS 846 LEI + S + RL + P +A + Sbjct 544 LEIISGRKNSSFGES-DGAQDLLTHAWRLWTNKKALDLVDPLIAENCQNSEVVRCIHIGL 602 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 C+ +P +RP+ T+ LT + + Sbjct 603 LCVQEDPAKRPAISTVFMMLTSNTVTLPVPRQPGFFIQCRAVKDPLDSDQSTTTKSFP 660 >sp|P14617|INSRR_CAVPO Insulin receptor-related protein OS=Cavia porcellus OX=10141 GN=INSRR PE=3 SV=1 Length=1300 Score = 252 bits (643), Expect = 3e-67, Method: Composition-based stats. Identities = 92/321 (29%), Positives = 148/321 (46%), Gaps = 32/321 (10%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT-GEMVAV 929 ++ D D + + IR+LG+G FG V G VA+ Sbjct 953 YTSVNPEYLSASDMYIPDEWEVPREQISIIRELGQGSFGMVYEGVAKGLEAGEESTPVAL 1012 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K + P+ R + +E +++ H+++ G QG+ +L ++ME + G L+ + Sbjct 1013 KTVNELASPRERIEFLKEASVMKAFQCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSH 1070 Query 990 LPR-----------HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 L L ++ A +I +GMAYL A ++HRDLAARN ++ D VK Sbjct 1071 LRSLRPEAENNPGIPRPALGDMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVK 1130 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 IGDFG+ + V E +YYR G PV W APE LK+ F SDVWSFGV L+E++T Sbjct 1131 IGDFGMTRDVYE-TDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVT-- 1187 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 L ++ ++ + + G L + CP ++ LM +CW+ Sbjct 1188 ------------LAEQPYQGLSNEQVLKFVMDGGVLEELEDCPHQLQELMSSCWQQNPRL 1235 Query 1159 RPTFENLIPILKTVHEKYQGQ 1179 RPTF + L ++ ++ + Sbjct 1236 RPTFTQI---LNSIQKELRPS 1253 Score = 243 bits (619), Expect = 3e-64, Method: Composition-based stats. Identities = 75/344 (22%), Positives = 129/344 (38%), Gaps = 49/344 (14%) Query 567 ARASPRTLNLSQL---SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 +P L+ S + V +++I+ + LGQG+ VYEG + +G+ Sbjct 954 TSVNPEYLSASDMYIPDEWEVPREQISIIRELGQGSFGMVYEGVAKGLEAGE-------- 1005 Query 624 EDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 + V LK ++ + + F + AS+M H+ + GV +G Sbjct 1006 -----------ESTPVALKTVNELASPRERIEFLKEASVMKAFQCHHVVRLLGVVSQGQP 1054 Query 683 NIMVTEYVEHGPLDVWLRRERGHVP---------MAWKMVVAQQLASALSYLENKNLVHG 733 +++ E + G L LR R + + +A ++A ++YL VH Sbjct 1055 TLVIMELMTRGDLKSHLRSLRPEAENNPGIPRPALGDMIQMAGEIADGMAYLAANKFVHR 1114 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGG 787 ++ RN ++++ +K+ D G+ + + + W+APE L G Sbjct 1115 DLAARNCMVSQ-------DFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDG 1167 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCPQ-LATLT 845 +T D W FG L EI E P Q S + F L E CP L L Sbjct 1168 I--FTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEDCPHQLQELM 1225 Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 S C P RP+F IL + + + + + Sbjct 1226 SSCWQQNPRLRPTFTQILNSIQKELRPSFRLLSFYHSPECQGGC 1269 >sp|Q8RX80|CRK18_ARATH Cysteine-rich receptor-like protein kinase 18 OS=Arabidopsis thaliana OX=3702 GN=CRK18 PE=2 SV=2 Length=659 Score = 243 bits (620), Expect = 3e-67, Method: Composition-based stats. Identities = 73/281 (26%), Positives = 110/281 (39%), Gaps = 18/281 (6%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG+V G +AVK L G +K E+ ++ L H ++ Sbjct 342 RNKLGKGGFGEVYKGMLM-----NGTEIAVKRLSKTSGQGEVE-FKNEVVVVAKLQHINL 395 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015 ++ G EK LV E+V SL +L R+ + I G+ YLH Sbjct 396 VRLLGFSLQGEEK--LLVYEFVSNKSLDYFLFDPTKRNQLDWTMRRNIIGGITRGILYLH 453 Query 1016 ---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 IHRDL A N+LLD D KI DFG+A+ + +PE Sbjct 454 QDSRLKIIHRDLKASNILLDADMNPKIADFGMARIFGVDQTVANT-GRVVGTFGYMSPEY 512 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL--ELIGIAQGQMTVLRLTELLER 1130 + +F SDV+SFGV + E+++ +S L L+ L ELL+ Sbjct 513 VTHGQFSMKSDVYSFGVLILEIISGKKNSSFYQMDGLVNNLVTYVWKLWENKSLHELLDP 572 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + H+ C + + RPT + +L Sbjct 573 FINQDFTSEEVIRYIHIGLLCVQENPADRPTMSTIHQMLTN 613 Score = 230 bits (586), Expect = 1e-62, Method: Composition-based stats. Identities = 58/360 (16%), Positives = 114/360 (32%), Gaps = 47/360 (13%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 SN + P L ++ + LG+G VY+G L Sbjct 308 ISNRRKQKQEMDLPTESVQFDLKTIESATSNFSERNKLGKGGFGEVYKGMLMNG------ 361 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 + +K L + + F +++++ H +L + G Sbjct 362 -------------------TEIAVKRLSKTSGQGEVEFKNEVVVVAKLQHINLVRLLGFS 402 Query 678 VRGPENIMVTEYVEHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENK---NLVH 732 ++G E ++V E+V + LD +L +R + + + + + YL ++H Sbjct 403 LQGEEKLLVYEFVSNKSLDYFLFDPTKRNQLDWTMRRNIIGGITRGILYLHQDSRLKIIH 462 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPG 786 ++ NILL K++D G+ + V +++PE + Sbjct 463 RDLKASNILLD-------ADMNPKIADFGMARIFGVDQTVANTGRVVGTFGYMSPEYVTH 515 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTS 846 G S D + FG +LEI + + + +L E L L Sbjct 516 G--QFSMKSDVYSFGVLILEIISGKKNSSFYQMDGLVNNLVTYVWKLWENKS--LHELLD 571 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + + T R I L +Q + ++ ++ L G Sbjct 572 PFINQDFTSEEVIRYIHIGLLCVQENPADRPTMSTIHQMLTNSSITLPVPLPPGFFFRNG 631 >sp|Q9VZI2|ACK_DROME Activated Cdc42 kinase Ack OS=Drosophila melanogaster OX=7227 GN=Ack PE=1 SV=2 Length=1073 Score = 250 bits (639), Expect = 3e-67, Method: Composition-based stats. Identities = 95/287 (33%), Positives = 146/287 (51%), Gaps = 20/287 (7%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQE 947 + H++ + LG+G FG V + + G VAVK LK+D P + +E Sbjct 116 CLIHEKDITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFRE 175 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQ 1005 + + L H ++++ G Q + ++ E GSL D L + L + ++ Sbjct 176 VQAMHALDHANLVRLYGVVLSQ---PMMMITELAERGSLLDTLRKQCRHTSLTIIWNWSV 232 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 QI GMAYL + ++HRDLA RNVLL +KIGDFGL +A+P+ + Y + E P Sbjct 233 QIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPF 292 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 W APE L+ +F +ASD W FGVTL+E+ + + +G+ Q+ L Sbjct 293 PWCAPESLRFRQFSHASDTWMFGVTLWEMFSFGEDP---------WVGLNGSQI----LR 339 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 ++ GERL +PD CP +VY +M CW+ + RPTF L L ++ Sbjct 340 KIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYLASM 386 Score = 221 bits (562), Expect = 1e-57, Method: Composition-based stats. Identities = 96/427 (22%), Positives = 154/427 (36%), Gaps = 58/427 (14%) Query 495 DGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 D +Q RL F D LE G P++R L A++ R+ L + Sbjct 36 DDLQVTRLAHFDYVLPDD---LERCGLGKPAIRRLMEAVRKKK------AHQWRKNILSK 86 Query 555 ----PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRV 610 + S+ AR S + + +K+IT LG G+ V G Sbjct 87 LIGGGKQPSSKKQSSAARESSQGNGTQLTCL--IHEKDITMGLKLGDGSFGVVRRGEW-- 142 Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH---HDIALAFYETASLMSQVSH 667 G+ + V +KVL + I F+ M + H Sbjct 143 ------------------SASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHALDH 184 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 +L ++GV + +M+TE E G L LR++ H + + Q+ + ++YLE Sbjct 185 ANLVRLYGVVL-SQPMMMITELAERGSLLDTLRKQCRHTSLTIIWNWSVQIVTGMAYLEQ 243 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-------ALSREERVERIPWLA 780 K +H ++ RN+LLA IK+ D G+ + E + PW A Sbjct 244 KRFLHRDLACRNVLLAAGN-------KIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCA 296 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRL--PEPS 837 PE L S A D W FG TL E+ GE P + S+ + RL P+ Sbjct 297 PESLR--FRQFSHASDTWMFGVTLWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDAC 354 Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897 P + + QC P +RP+F + L + P + + + + Sbjct 355 PPDVYAMMLQCWDKTPAERPTFAALKEYLASMSPPVMRASRSHHESKGLQIEPGDTIAII 414 Query 898 KKIRDLG 904 +L Sbjct 415 DGRHELK 421 >sp|P55144|TYRO3_MOUSE Tyrosine-protein kinase receptor TYRO3 OS=Mus musculus OX=10090 GN=Tyro3 PE=1 SV=2 Length=880 Score = 248 bits (632), Expect = 3e-67, Method: Composition-based stats. Identities = 87/282 (31%), Positives = 130/282 (46%), Gaps = 28/282 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 LG+G FG V DG+ VAVK LKAD + +E ++ H H+ K Sbjct 514 LGKGEFGSVREAQLK-QEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAK 572 Query 962 YKGCCED---QGEKSL-QLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEG 1010 G +G + +++ ++ G L +L ++ L L+ F I G Sbjct 573 LVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLVRFMVDIACG 632 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 M YL ++++IHRDLAARN +L D V + DFGL++ + G +YYR PV W A Sbjct 633 MEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSG-DYYRQGCASKLPVKWLAL 691 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E L + + SDVW+FGVT++E++T + + L Sbjct 692 ESLADNLYTVHSDVWAFGVTMWEIMTRGQ--------------TPYAGIENAEIYNYLIG 737 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 G RL +P +C EVY LM CW + RP+F L L+ + Sbjct 738 GNRLKQPPECMEEVYDLMYQCWSADPKQRPSFTCLRMELENI 779 Score = 234 bits (597), Expect = 1e-62, Method: Composition-based stats. Identities = 70/316 (22%), Positives = 128/316 (41%), Gaps = 51/316 (16%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 +L + +++ T LG+G +V E +L+ E G + Sbjct 497 KLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQED---------------------GSFV 535 Query 638 RVVLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEY 689 +V +K+L F A+ M + H H+A + GV +R P +++ + Sbjct 536 KVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF 595 Query 690 VEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 ++HG L +L R ++P+ + +A + YL ++N +H ++ RN +LA Sbjct 596 MKHGDLHAFLLASRIGENPFNLPLQTLVRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE 655 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKW 798 + ++D G+ S + + + WLA E L + D W Sbjct 656 -------DMTVCVADFGLSRKIYSGDYYRQGCASKLPVKWLALESLADNL--YTVHSDVW 706 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 FG T+ EI G+ P +E ++ +RL P ++ L QC + +P QR Sbjct 707 AFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQPPECMEEVYDLMYQCWSADPKQR 766 Query 857 PSFRTILRDLTRLQPH 872 PSF + +L + H Sbjct 767 PSFTCLRMELENILGH 782 >sp|Q9T058|Y4119_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At4g11900 OS=Arabidopsis thaliana OX=3702 GN=At4g11900 PE=2 SV=1 Length=849 Score = 247 bits (631), Expect = 3e-67, Method: Composition-based stats. Identities = 71/332 (21%), Positives = 120/332 (36%), Gaps = 17/332 (5%) Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 C +R + + L L D N + + + LGEG Sbjct 488 CCISSRIRRKKKQRDEKHSRELLEGGLIDDAGENMCYLNLHDIMVATNSFSRKKKLGEGG 547 Query 908 FGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 FG V G VA+K L Q + +K E+ ++ L H+++++ G C Sbjct 548 FGPVYKG-----KLPNGMEVAIKRLSKKSS-QGLTEFKNEVVLIIKLQHKNLVRLLGYCV 601 Query 968 DQGEKSLQLVMEYVPL----GSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA---QHYI 1020 + EK L+ EY+ G L D L + + G+ YLH I Sbjct 602 EGDEK--LLIYEYMSNKSLDGLLFDSLKSRELDWETRMKIVNGTTRGLQYLHEYSRLRII 659 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDL A N+LLD++ KI DFG A+ + + + +PE Sbjct 660 HRDLKASNILLDDEMNPKISDFGTARIFG-CKQIDDSTQRIVGTFGYMSPEYALGGVISE 718 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFL-ELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SD++SFGV L E+++ +++ LI + +++ + Sbjct 719 KSDIYSFGVLLLEIISGKKATRFVHNDQKHSLIAYEWESWCETKGVSIIDEPMCCSYSLE 778 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 H+ C + RP ++ +L Sbjct 779 EAMRCIHIALLCVQDHPKDRPMISQIVYMLSN 810 Score = 244 bits (623), Expect = 3e-66, Method: Composition-based stats. Identities = 74/383 (19%), Positives = 119/383 (31%), Gaps = 74/383 (19%) Query 519 WGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCL--------PQPGETSNLIIMRGARAS 570 + + L L A CF CC+ Q E + ++ G Sbjct 457 RKTEHSKGKSIVLPLVLASLVATAACFVGLYCCISSRIRRKKKQRDEKHSRELLEGGLID 516 Query 571 PRTLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 N+ L+ H + ++ LG+G VY+G+L Sbjct 517 DAGENMCYLNLHDIMVATNSFSRKKKLGEGGFGPVYKGKLPNG----------------- 559 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 + V +K L F L+ ++ H +L + G CV G E +++ E Sbjct 560 --------MEVAIKRLSKKSSQGLTEFKNEVVLIIKLQHKNLVRLLGYCVEGDEKLLIYE 611 Query 689 YVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLA 743 Y+ + LD L + W +M + L YL ++H ++ NILL Sbjct 612 YMSNKSLDGLLFDSLKSRELDWETRMKIVNGTTRGLQYLHEYSRLRIIHRDLKASNILLD 671 Query 744 RLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDK 797 K+SD G S + V +++PE GG +S D Sbjct 672 -------DEMNPKISDFGTARIFGCKQIDDSTQRIVGTFGYMSPEYALGGV--ISEKSDI 722 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL------------PEPSCPQLATLT 845 + FG LLEI G+ + +K + P L Sbjct 723 YSFGVLLLEIIS-GKKATRFVHNDQKHSLIAYEWESWCETKGVSIIDEPMCCSYSLEEAM 781 Query 846 S------QCLTYEPTQRPSFRTI 862 C+ P RP I Sbjct 782 RCIHIALLCVQDHPKDRPMISQI 804 >sp|Q06418|TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3 OS=Homo sapiens OX=9606 GN=TYRO3 PE=1 SV=1 Length=890 Score = 248 bits (633), Expect = 3e-67, Method: Composition-based stats. Identities = 86/282 (30%), Positives = 130/282 (46%), Gaps = 28/282 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 LG+G FG V DG+ VAVK LKAD + +E ++ H H+ K Sbjct 524 LGKGEFGSVREAQLK-QEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAK 582 Query 962 YKGCCED---QGEKSL-QLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEG 1010 G +G + +++ ++ G L +L ++ L L+ F I G Sbjct 583 LVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLIRFMVDIACG 642 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 M YL ++++IHRDLAARN +L D V + DFGL++ + G +YYR PV W A Sbjct 643 MEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSG-DYYRQGCASKLPVKWLAL 701 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E L + + SDVW+FGVT++E++T + + L Sbjct 702 ESLADNLYTVQSDVWAFGVTMWEIMTRGQ--------------TPYAGIENAEIYNYLIG 747 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 G RL +P +C +VY LM CW + RP+F L L+ + Sbjct 748 GNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMELENI 789 Score = 234 bits (597), Expect = 1e-62, Method: Composition-based stats. Identities = 69/313 (22%), Positives = 126/313 (40%), Gaps = 51/313 (16%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 +L + +++ T LG+G +V E +L+ E G + Sbjct 507 KLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQED---------------------GSFV 545 Query 638 RVVLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRG------PENIMVTEY 689 +V +K+L F A+ M + H H+A + GV +R P +++ + Sbjct 546 KVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF 605 Query 690 VEHGPLDVWLRRER-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 ++HG L +L R ++P+ + +A + YL ++N +H ++ RN +LA Sbjct 606 MKHGDLHAFLLASRIGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAE 665 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKW 798 + ++D G+ S + + + WLA E L + D W Sbjct 666 -------DMTVCVADFGLSRKIYSGDYYRQGCASKLPVKWLALESLADNL--YTVQSDVW 716 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 FG T+ EI G+ P +E ++ +RL P + L QC + +P QR Sbjct 717 AFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQPPECMEDVYDLMYQCWSADPKQR 776 Query 857 PSFRTILRDLTRL 869 PSF + +L + Sbjct 777 PSFTCLRMELENI 789 >sp|C0LGQ7|Y4245_ARATH Probable LRR receptor-like serine/threonine-protein kinase At4g20450 OS=Arabidopsis thaliana OX=3702 GN=At4g20450 PE=1 SV=1 Length=898 Score = 248 bits (633), Expect = 3e-67, Method: Composition-based stats. Identities = 77/299 (26%), Positives = 128/299 (43%), Gaps = 17/299 (6%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 + + + R LGEG FG V N E VAVK L ++ Q Sbjct 574 MVANKRSYTYEEVAVITNNFERPLGEGGFGVVYHG-----NVNDNEQVAVKVL-SESSAQ 627 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSI 995 +K E+D+L ++H +++ G C++ + L L+ EY+ G+L+ +L R + Sbjct 628 GYKQFKAEVDLLLRVHHINLVTLVGYCDEG--QHLVLIYEYMSNGNLKQHLSGENSRSPL 685 Query 996 GLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 L A + +G+ YLH IHRD+ + N+LLDN+ K+GDFGL+++ P G Sbjct 686 SWENRLRIAAETAQGLEYLHIGCKPPMIHRDIKSMNILLDNNFQAKLGDFGLSRSFPVGS 745 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 E + SP + PE + SDV+SFGV L E++T K + Sbjct 746 ETHVSTNVAGSP-GYLDPEYYRTNWLTEKSDVFSFGVVLLEIITSQPVIDQTREK-SHIG 803 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 ++T + +++ + L +C +S RP + L+ Sbjct 804 EWVGFKLTNGDIKNIVDPSMNGDYDSSSLWKALELAMSCVSPSSSGRPNMSQVANELQE 862 Score = 213 bits (542), Expect = 1e-55, Method: Composition-based stats. Identities = 70/330 (21%), Positives = 110/330 (33%), Gaps = 60/330 (18%) Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 A S N ++ V LG+G VY G + Sbjct 568 KASRSSMVANKRSYTYEEVAVITNNFERPLGEGGFGVVYHGNVNDNE------------- 614 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 +V +KVL S F L+ +V H +L + G C G ++ Sbjct 615 ------------QVAVKVLSESSAQGYKQFKAEVDLLLRVHHINLVTLVGYCDEGQHLVL 662 Query 686 VTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNI 740 + EY+ +G L L E P++W ++ +A + A L YL ++H ++ NI Sbjct 663 IYEYMSNGNLKQHLSGENSRSPLSWENRLRIAAETAQGLEYLHIGCKPPMIHRDIKSMNI 722 Query 741 LLARLGLAEGTSPFIKLSDPGVGLG-ALSREERVER-----IPWLAPECLPGGANSLSTA 794 LL + KL D G+ + E V +L PE N L+ Sbjct 723 LLDN-------NFQAKLGDFGLSRSFPVGSETHVSTNVAGSPGYLDPEYYRT--NWLTEK 773 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPS---EKEHFYQRQHRLPEPSCPQLA--------- 842 D + FG LLEI Q+R S E F + P + Sbjct 774 SDVFSFGVVLLEIITSQPVIDQTREKSHIGEWVGFKLTNGDIKNIVDPSMNGDYDSSSLW 833 Query 843 ---TLTSQCLTYEPTQRPSFRTILRDLTRL 869 L C++ + RP+ + +L Sbjct 834 KALELAMSCVSPSSSGRPNMSQVANELQEC 863 >sp|Q9LZF8|PCRK2_ARATH Serine/threonine-protein kinase PCRK2 OS=Arabidopsis thaliana OX=3702 GN=PCRK2 PE=1 SV=1 Length=420 Score = 236 bits (602), Expect = 3e-67, Method: Composition-based stats. Identities = 75/283 (27%), Positives = 126/283 (45%), Gaps = 13/283 (5%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG FG V D + ++ VAVK L G Q W E++ L + H +++K Sbjct 87 IGEGGFGCVFWGTIKNLEDPSKKIEVAVKQL-GKRGLQGHKEWVTEVNFLGVVEHSNLVK 145 Query 962 YKGCCEDQGEKSL--QLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA 1016 G C + E+ + LV EY+P S+ +L S + L AQ G+ YLH Sbjct 146 LLGHCAEDDERGIQRLLVYEYMPNQSVEFHLSPRSPTVLTWDLRLRIAQDAARGLTYLHE 205 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + I RD + N+LLD + K+ DFGLA+ P + V D + + APE + Sbjct 206 EMDFQIIFRDFKSSNILLDENWTAKLSDFGLARLGPSPGSSH-VSTDVVGTMGYAAPEYI 264 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMT-VLRLTELLERG 1131 + + SDVW +GV +YEL+T ++ P +L+ + ++ R +++ Sbjct 265 QTGRLTSKSDVWGYGVFIYELITGRRPLDRNKPKGEQKLLEWVRPYLSDTRRFRLIVDPR 324 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 K ++ + C A RP ++ ++ + E Sbjct 325 LEGKYMIKSVQKLAVVANLCLTRNAKARPKMSEVLEMVTKIVE 367 Score = 211 bits (538), Expect = 1e-58, Method: Composition-based stats. Identities = 72/389 (19%), Positives = 135/389 (35%), Gaps = 64/389 (16%) Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGS 613 S+ S R NL + + + + ++ +G+G V+ G ++ Sbjct 46 STVSSTGRNSNTSMSARENNLREFTIGDLKSATRNFSRSGMIGEGGFGCVFWGTIKNL-- 103 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 D +++ V +K L + + + V H++L + Sbjct 104 -----------------EDPSKKIEVAVKQLGKRGLQGHKEWVTEVNFLGVVEHSNLVKL 146 Query 674 HGVCVRGPE----NIMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENK 728 G C E ++V EY+ + ++ L R + ++ +AQ A L+YL + Sbjct 147 LGHCAEDDERGIQRLLVYEYMPNQSVEFHLSPRSPTVLTWDLRLRIAQDAARGLTYLHEE 206 Query 729 ---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWL 779 ++ + NILL + KLSD G+ S + V + + Sbjct 207 MDFQIIFRDFKSSNILLDE-------NWTAKLSDFGLARLGPSPGSSHVSTDVVGTMGYA 259 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF---------YQRQ 830 APE + G L++ D WG+G + E+ G PL P ++ R+ Sbjct 260 APEYIQTG--RLTSKSDVWGYGVFIYELI-TGRRPLDRNKPKGEQKLLEWVRPYLSDTRR 316 Query 831 HRL----------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880 RL S +LA + + CLT RP +L +T++ + Sbjct 317 FRLIVDPRLEGKYMIKSVQKLAVVANLCLTRNAKARPKMSEVLEMVTKIVEASSPGNGGK 376 Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 P + K + + +G G Sbjct 377 KPQLVPLKSQETSRVEEGKNKKVLDGAEG 405 >sp|Q9T0J1|CRK26_ARATH Cysteine-rich receptor-like protein kinase 26 OS=Arabidopsis thaliana OX=3702 GN=CRK26 PE=2 SV=1 Length=665 Score = 243 bits (620), Expect = 4e-67, Method: Composition-based stats. Identities = 72/327 (22%), Positives = 130/327 (40%), Gaps = 19/327 (6%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 + + + ++ + + LGEG FG V G+ +AV Sbjct 317 ENKHENENISTDSMKFDFSVLQDATSHFSLENKLGEGGFGAVYKGVL-----SDGQKIAV 371 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K L + Q + +K E ++ L H +++K G + E+ LV E++P SL + Sbjct 372 KRLSKNA-QQGETEFKNEFLLVAKLQHRNLVKLLGYSIEGTER--LLVYEFLPHTSLDKF 428 Query 990 L----PRHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDF 1042 + + + + G+ YLH IHRDL A N+LLD + KI DF Sbjct 429 IFDPIQGNELEWEIRYKIIGGVARGLLYLHQDSRLRIIHRDLKASNILLDEEMTPKIADF 488 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSS 1101 G+A+ H R + APE + +F + +DV+SFGV + E+++ +S Sbjct 489 GMARLFDIDHTTQRYTNRIVGTFGYMAPEYVMHGQFSFKTDVYSFGVLVLEIISGKKNSG 548 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERL--PRPDKCPCEVYHLMKNCWETEASFR 1159 S +LI A L+++ ++ C + + + R Sbjct 549 FSSEDSMGDLISFAWRNWKEGVALNLVDKILMTMSSYSSNMIMRCINIGLLCVQEKVAER 608 Query 1160 PTFENLIPILK-TVHEKYQGQAPSVFS 1185 P+ +++ +L + P+ FS Sbjct 609 PSMASVVLMLDGHTIALSEPSKPAFFS 635 Score = 219 bits (558), Expect = 5e-59, Method: Composition-based stats. Identities = 62/409 (15%), Positives = 119/409 (29%), Gaps = 67/409 (16%) Query 469 GLYLIHWSTSHPYRLILTVAQRS--QAPDGMQSLRLRKFPIEQQDGAFVLEGWG-RSFPS 525 G Y++ S +L A D + P G ++ Sbjct 227 GSYVMSPSC------MLAYAPWRFYDPVDTDDPSSVPATPSRPPKNETRSVTQGDKNRGV 280 Query 526 VRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVD 585 + L A + + L + N S + Sbjct 281 PKALIFASASVAIVVLFIVLLVVFLKLRRKENIRNSENKHENENISTDSMKFDFSVLQDA 340 Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + + LG+G VY+G L ++ +K L Sbjct 341 TSHFSLENKLGEGGFGAVYKGVLSDGQ-------------------------KIAVKRLS 375 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR--ER 703 + F L++++ H +L + G + G E ++V E++ H LD ++ + Sbjct 376 KNAQQGETEFKNEFLLVAKLQHRNLVKLLGYSIEGTERLLVYEFLPHTSLDKFIFDPIQG 435 Query 704 GHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + + + +A L YL ++H ++ NILL K++D Sbjct 436 NELEWEIRYKIIGGVARGLLYLHQDSRLRIIHRDLKASNILLDEEMTP-------KIADF 488 Query 761 GVGL-------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ V ++APE + G S D + FG +LEI + Sbjct 489 GMARLFDIDHTTQRYTNRIVGTFGYMAPEYVMHG--QFSFKTDVYSFGVLVLEIISGKKN 546 Query 814 --PLQSRSPSEKEHFYQRQH----------RLPEPSCPQLATLTSQCLT 850 S + F R ++ + + +C+ Sbjct 547 SGFSSEDSMGDLISFAWRNWKEGVALNLVDKILMTMSSYSSNMIMRCIN 595 >sp|Q9LDM5|CRK31_ARATH Putative cysteine-rich receptor-like protein kinase 31 OS=Arabidopsis thaliana OX=3702 GN=CRK31 PE=3 SV=1 Length=666 Score = 243 bits (620), Expect = 4e-67, Method: Composition-based stats. Identities = 61/326 (19%), Positives = 109/326 (33%), Gaps = 64/326 (20%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 SP++L + V ++ + LGQG VY+G L Sbjct 320 TSPQSLQF-DFTTIEVATDNFSRNNKLGQGGFGEVYKGML-------------------- 358 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 E + +K L + F +++++ H +L + G C+ E I+V E Sbjct 359 -----PNETEIAVKRLSSNSGQGTQEFKNEVVIVAKLQHKNLVRLLGFCIERDEQILVYE 413 Query 689 YVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNILLA 743 +V + LD +L + + W + + + L YL + ++H ++ NILL Sbjct 414 FVSNKSLDYFLFDPKMKSQLDWKRRYNIIGGVTRGLLYLHQDSRLTIIHRDIKASNILLD 473 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDK 797 K++D G+ + V ++ PE + G ST D Sbjct 474 -------ADMNPKIADFGMARNFRVDQTEDQTGRVVGTFGYMPPEYVTHG--QFSTKSDV 524 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------------ 839 + FG +LEI + + + RL P Sbjct 525 YSFGVLILEIVCGKKNSSFFQMDDSGGNLVTHVWRLWNNDSPLDLIDPAIKESYDNDEVI 584 Query 840 QLATLTSQCLTYEPTQRPSFRTILRD 865 + + C+ P RP TI + Sbjct 585 RCIHIGILCVQETPADRPEMSTIFQM 610 Score = 242 bits (618), Expect = 7e-67, Method: Composition-based stats. Identities = 69/315 (22%), Positives = 119/315 (38%), Gaps = 18/315 (6%) Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE 925 L+ H D+ + + LG+G FG+V Sbjct 308 YKTLKYHTDDDMTSPQSLQFDFTTIEVATDNFSRNNKLGQGGFGEVYKGMLPNE-----T 362 Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 +AVK L ++ G Q +K E+ I+ L H+++++ G C ++ E+ LV E+V S Sbjct 363 EIAVKRLSSNSG-QGTQEFKNEVVIVAKLQHKNLVRLLGFCIERDEQ--ILVYEFVSNKS 419 Query 986 LRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVK 1038 L +L + + + + G+ YLH IHRD+ A N+LLD D K Sbjct 420 LDYFLFDPKMKSQLDWKRRYNIIGGVTRGLLYLHQDSRLTIIHRDIKASNILLDADMNPK 479 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 I DFG+A+ + + PE + +F SDV+SFGV + E++ Sbjct 480 IADFGMARNFRVDQTEDQT-GRVVGTFGYMPPEYVTHGQFSTKSDVYSFGVLILEIVCGK 538 Query 1099 D--SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156 S L+ +L++ + + H+ C + Sbjct 539 KNSSFFQMDDSGGNLVTHVWRLWNNDSPLDLIDPAIKESYDNDEVIRCIHIGILCVQETP 598 Query 1157 SFRPTFENLIPILKT 1171 + RP + +L Sbjct 599 ADRPEMSTIFQMLTN 613 >sp|Q9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 OS=Homo sapiens OX=9606 GN=STK24 PE=1 SV=1 Length=443 Score = 236 bits (603), Expect = 4e-67, Method: Composition-based stats. Identities = 68/266 (26%), Positives = 118/266 (44%), Gaps = 24/266 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G FG+V + ++ T ++VA+K + + +QEI +L ++ K Sbjct 41 KIGKGSFGEV----FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTK 96 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 Y G + L ++MEY+ GS D L + Q+ ++I +G+ YLH++ IH Sbjct 97 YYGSYLKDTK--LWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIH 154 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RD+ A NVLL VK+ DFG+A + + R FW APE +K+ + Sbjct 155 RDIKAANVLLSEHGEVKLADFGVAGQLTD---TQIKRNTFVGTPFWMAPEVIKQSAYDSK 211 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 +D+WS G+T EL ++ +++ L+ + Sbjct 212 ADIWSLGITAIELARGEPP---------------HSELHPMKVLFLIPKNNPPTLEGNYS 256 Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167 + ++ C E SFRPT + L+ Sbjct 257 KPLKEFVEACLNKEPSFRPTAKELLK 282 Score = 217 bits (553), Expect = 2e-60, Method: Composition-based stats. Identities = 70/337 (21%), Positives = 126/337 (37%), Gaps = 63/337 (19%) Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRT 601 + RR LP PG ++NL +A P L T+L +G+G+ Sbjct 9 GLALNKRRATLPHPGGSTNL------KADPEEL--------------FTKLEKIGKGSFG 48 Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETAS 660 V++G D + V +K++D D + + Sbjct 49 EVFKGI------------------------DNRTQKVVAIKIIDLEEAEDEIEDIQQEIT 84 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 ++SQ ++ +G ++ + ++ EY+ G L E G + + +++ Sbjct 85 VLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL--EPGPLDETQIATILREILK 142 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGALSREERVERI 776 L YL ++ +H ++ N+LL+ G +KL+D GV + R V Sbjct 143 GLDYLHSEKKIHRDIKAANVLLSEHGE-------VKLADFGVAGQLTDTQIKRNTFVGTP 195 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH--RLP 834 W+APE + A + D W G T +E+ GE P P + + + L Sbjct 196 FWMAPEVIKQSA--YDSKADIWSLGITAIELA-RGEPPHSELHPMKVLFLIPKNNPPTLE 252 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 L CL EP+ RP+ + +L+ L+ Sbjct 253 GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRN 289 >sp|Q39086|SD17_ARATH Receptor-like serine/threonine-protein kinase SD1-7 OS=Arabidopsis thaliana OX=3702 GN=SD17 PE=1 SV=1 Length=843 Score = 246 bits (629), Expect = 4e-67, Method: Composition-based stats. Identities = 74/287 (26%), Positives = 114/287 (40%), Gaps = 21/287 (7%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 LG+G FG V G+ +AVK L Q + E+ ++ L Sbjct 517 NNFSNDNKLGQGGFGIVYKGRL-----LDGKEIAVKRLSK-MSSQGTDEFMNEVRLIAKL 570 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEG 1010 H ++++ GCC D+GEK L+ EY+ SL +L ++ + I G Sbjct 571 QHINLVRLLGCCVDKGEK--MLIYEYLENLSLDSHLFDQTRSSNLNWQKRFDIINGIARG 628 Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH IHRDL A NVLLD + KI DFG+A+ R + Sbjct 629 LLYLHQDSRCRIIHRDLKASNVLLDKNMTPKISDFGMARIFGREETEANTRR-VVGTYGY 687 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTE 1126 +PE + F SDV+SFGV L E+++ + L L+G E Sbjct 688 MSPEYAMDGIFSMKSDVFSFGVLLLEIISGKRNKGFYNSNRDLNLLGFVWRHWKEGNELE 747 Query 1127 LLERGERLPRPDKCPC----EVYHLMKNCWETEASFRPTFENLIPIL 1169 +++ K P + C + A RP +++ +L Sbjct 748 IVDPINIDSLSSKFPTHEILRCIQIGLLCVQERAEDRPVMSSVMVML 794 Score = 226 bits (575), Expect = 5e-60, Method: Composition-based stats. Identities = 51/253 (20%), Positives = 87/253 (34%), Gaps = 45/253 (18%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + + LGQG VY+GRL + +K L Sbjct 515 ATNNFSNDNKLGQGGFGIVYKGRLLDGK-------------------------EIAVKRL 549 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 F L++++ H +L + G CV E +++ EY+E+ LD L + Sbjct 550 SKMSSQGTDEFMNEVRLIAKLQHINLVRLLGCCVDKGEKMLIYEYLENLSLDSHLFDQTR 609 Query 705 HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + W + + +A L YL ++H ++ N+LL + + K+SD Sbjct 610 SSNLNWQKRFDIINGIARGLLYLHQDSRCRIIHRDLKASNVLLDK-------NMTPKISD 662 Query 760 PGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ + V +++PE G S D + FG LLEI Sbjct 663 FGMARIFGREETEANTRRVVGTYGYMSPEYAMDGI--FSMKSDVFSFGVLLLEIISGKRN 720 Query 814 PLQSRSPSEKEHF 826 S + Sbjct 721 KGFYNSNRDLNLL 733 >sp|P18160|SPLA_DICDI Dual specificity protein kinase splA OS=Dictyostelium discoideum OX=44689 GN=splA PE=1 SV=3 Length=2410 Score = 253 bits (645), Expect = 4e-67, Method: Composition-based stats. Identities = 85/297 (29%), Positives = 131/297 (44%), Gaps = 46/297 (15%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEH 958 + +G+G FG+V + T+ VA+K + D ++ E+ IL L H + Sbjct 2119 QTIGKGFFGEVKRGYWRETD------VAIKIIYRDQFKTKSSLVMFQNEVGILSKLRHPN 2172 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ----LLLFAQQICEGMAYL 1014 ++++ G C GE +V E++ GSLR +L H L Q L A I +GM YL Sbjct 2173 VVQFLGACTAGGEDHHCIVTEWMGGGSLRQFLTDHFNLLEQNPHIRLKLALDIAKGMNYL 2232 Query 1015 H--AQHYIHRDLAARNVLLDN-------------DRLVKIGDFGLAKAVPEGHEYYRVRE 1059 H +HRDL++RN+LLD+ D KI DFGL++ + + Sbjct 2233 HGWTPPILHRDLSSRNILLDHNIDPKNPVVSSRQDIKCKISDFGLSR-LKMEQASQMTQS 2291 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQ 1118 G P + APE K SDV+S+G+ L+ELLT + Q P K L Sbjct 2292 VGCIP--YMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAY---- 2345 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 R P P + ++ CW++ RPTF+ +I LK + ++ Sbjct 2346 -----------ESYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQIIVHLKEMEDQ 2391 Score = 227 bits (579), Expect = 5e-59, Method: Composition-based stats. Identities = 65/315 (21%), Positives = 121/315 (38%), Gaps = 51/315 (16%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 S + +D E+ +G+G V G R E V Sbjct 2106 SEYEIDFNELEFGQTIGKGFFGEVKRGYWR--------------------------ETDV 2139 Query 640 VLKVLDPSHHDIALA---FYETASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEHGP 694 +K++ + F ++S++ H ++ G C G E + +VTE++ G Sbjct 2140 AIKIIYRDQFKTKSSLVMFQNEVGILSKLRHPNVVQFLGACTAGGEDHHCIVTEWMGGGS 2199 Query 695 LDVWLRRERGHVPMA--WKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLAEG 750 L +L + ++ +A +A ++YL ++H ++ RNILL + Sbjct 2200 LRQFLTDHFNLLEQNPHIRLKLALDIAKGMNYLHGWTPPILHRDLSSRNILLDHNIDPKN 2259 Query 751 ------TSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGF 800 K+SD G+ + + + V IP++APE G +N S D + + Sbjct 2260 PVVSSRQDIKCKISDFGLSRLKMEQASQMTQSVGCIPYMAPEVFKGDSN--SEKSDVYSY 2317 Query 801 GATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857 G L E+ E P Q P + H + + +P + + + +QC P RP Sbjct 2318 GMVLFELLTSDE-PQQDMKPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDSNPDSRP 2376 Query 858 SFRTILRDLTRLQPH 872 +F+ I+ L ++ Sbjct 2377 TFKQIIVHLKEMEDQ 2391 >sp|H2L099|GCK1_CAEEL Germinal center kinase 1 OS=Caenorhabditis elegans OX=6239 GN=gck-1 PE=1 SV=1 Length=653 Score = 242 bits (618), Expect = 5e-67, Method: Composition-based stats. Identities = 70/271 (26%), Positives = 119/271 (44%), Gaps = 23/271 (8%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 K +G G FG+V Y ++ TG +VA+K + + +QEI +L Sbjct 34 FTKQERIGRGSFGEV----YKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDS 89 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016 +++ KY G + L ++MEY+ GS D + + + + ++I +G+ YLH+ Sbjct 90 QYVTKYFGSFLKGSK--LWIIMEYLGGGSALDLTKSGKLDESHIAVILREILKGLEYLHS 147 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + IHRD+ A NVL+ VK+ DFG+A + E + R FW APE +K+ Sbjct 148 ERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTE---TVKKRITFVGSPFWMAPELIKQS 204 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 + Y +D+WS G+T EL + S L I + VL+ ++ Sbjct 205 SYDYKADIWSLGITAIELANG-EPPHSDLHPMRVLFLIPKNPPPVLQGSQ---------- 253 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 ++ C + RP+ L+ Sbjct 254 ---WSKPFKEFVEMCLNKDPENRPSASTLLK 281 Score = 201 bits (512), Expect = 4e-53, Method: Composition-based stats. Identities = 57/311 (18%), Positives = 110/311 (35%), Gaps = 50/311 (16%) Query 571 PRTLNLSQLSFHRVDQKE------ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 PR + + + R+ ++ T+ +G+G+ VY+G Sbjct 10 PRQADDDSMKWDRIYIQKLDPEVIFTKQERIGRGSFGEVYKGI----------------- 52 Query 625 DPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 D V +K++D D + ++SQ ++ G ++G + Sbjct 53 -------DNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSKL 105 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 ++ EY+ G + G + + V+ +++ L YL ++ +H ++ N+L++ Sbjct 106 WIIMEYLGGGSALDL--TKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVS 163 Query 744 RLGLAEGTSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 G +K++D GV R V W+APE + + D W Sbjct 164 EHGD-------VKVADFGVAGQLTETVKKRITFVGSPFWMAPELIKQSSYDY--KADIWS 214 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP---EPSCPQLATLTSQCLTYEPTQR 856 G T +E+ +GE P P + CL +P R Sbjct 215 LGITAIELA-NGEPPHSDLHPMRVLFLIPKNPPPVLQGSQWSKPFKEFVEMCLNKDPENR 273 Query 857 PSFRTILRDLT 867 PS T+L+ Sbjct 274 PSASTLLKHQF 284 >sp|Q9SN43|CIPKC_ARATH CBL-interacting serine/threonine-protein kinase 12 OS=Arabidopsis thaliana OX=3702 GN=CIPK12 PE=1 SV=1 Length=489 Score = 238 bits (606), Expect = 5e-67, Method: Composition-based stats. Identities = 69/268 (26%), Positives = 112/268 (42%), Gaps = 26/268 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960 LG G F KV L N T E VA+K + + + + K+EI ILR + H +I+ Sbjct 32 LGHGTFAKVYL----ARNVKTNESVAIKVIDKEKVLKGGLIAHIKREISILRRVRHPNIV 87 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + + + + VMEYV G L + + + + + QQ+ + + HA+ Sbjct 88 QLFEVMATKAK--IYFVMEYVRGGELFNKVAKGRLKEEVARKYFQQLISAVTFCHARGVY 145 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 HRDL N+LLD + +K+ DFGL+ + + +P + APE L + Sbjct 146 HRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPA-YVAPEVLARKGYDA 204 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 D+WS GV L+ L+ V+ + + + RGE P Sbjct 205 AKVDIWSCGVILFVLMAGYLPFHD---------------RNVMAMYKKIYRGE-FRCPRW 248 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 E+ L+ ET R TF ++ Sbjct 249 FSTELTRLLSKLLETNPEKRFTFPEIME 276 Score = 184 bits (466), Expect = 2e-48, Method: Composition-based stats. Identities = 58/307 (19%), Positives = 97/307 (32%), Gaps = 45/307 (15%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH- 648 LG GT VY R+ V +KV+D Sbjct 27 EMGKLLGHGTFAKVYLA------------------------RNVKTNESVAIKVIDKEKV 62 Query 649 --HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 + S++ +V H ++ + V + V EYV G L + +G + Sbjct 63 LKGGLIAHIKREISILRRVRHPNIVQLFEVMATKAKIYFVMEYVRGGELFN--KVAKGRL 120 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--- 763 QQL SA+++ + + H ++ N+LL G +K+SD G+ Sbjct 121 KEEVARKYFQQLISAVTFCHARGVYHRDLKPENLLLDENG-------NLKVSDFGLSAVS 173 Query 764 ---LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 ++APE L + +D W G L + G P R+ Sbjct 174 DQIRQDGLFHTFCGTPAYVAPEVLARKGYD-AAKVDIWSCGVIL-FVLMAGYLPFHDRNV 231 Query 821 SEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 R R P +L L S+ L P +R +F I+ + + Sbjct 232 MAMYKKIYRGEFRCPRWFSTELTRLLSKLLETNPEKRFTFPEIMENSWFKKGFKHIKFYV 291 Query 880 VNPDSPA 886 + Sbjct 292 EDDKLCN 298 >sp|Q99KH8|STK24_MOUSE Serine/threonine-protein kinase 24 OS=Mus musculus OX=10090 GN=Stk24 PE=1 SV=1 Length=431 Score = 236 bits (601), Expect = 5e-67, Method: Composition-based stats. Identities = 70/266 (26%), Positives = 121/266 (45%), Gaps = 24/266 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G FG+V + ++ T ++VA+K + + +QEI +L ++ K Sbjct 29 KIGKGSFGEV----FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTK 84 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 Y G + L ++MEY+ GS D L + Q+ ++I +G+ YLH++ IH Sbjct 85 YYGSYLKDTK--LWIIMEYLGGGSALDLLEPGPLDEIQIATILREILKGLDYLHSEKKIH 142 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RD+ A NVLL VK+ DFG+A + + R FW APE +K+ + Sbjct 143 RDIKAANVLLSEHGEVKLADFGVAGQLTD---TQIKRNTFVGTPFWMAPEVIKQSAYDSK 199 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 +D+WS G+T EL + PP ++ +++ L+ + Sbjct 200 ADIWSLGITAIEL-----AKGEPP----------HSELHPMKVLFLIPKNNPPTLEGNYS 244 Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167 + ++ C E SFRPT + L+ Sbjct 245 KPLKEFVEACLNKEPSFRPTAKELLK 270 Score = 213 bits (542), Expect = 5e-59, Method: Composition-based stats. Identities = 63/310 (20%), Positives = 119/310 (38%), Gaps = 44/310 (14%) Query 570 SPRTLNLSQLSFHRVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 SP L + + D +E T+L +G+G+ V++G Sbjct 4 SPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGI--------------------- 42 Query 629 PGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 D + V +K++D D + +++SQ ++ +G ++ + ++ Sbjct 43 ---DNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIM 99 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 EY+ G L E G + + +++ L YL ++ +H ++ N+LL+ G Sbjct 100 EYLGGGSALDLL--EPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE 157 Query 748 AEGTSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +KL+D GV + R V W+APE + A + D W G T Sbjct 158 -------VKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSA--YDSKADIWSLGIT 208 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861 +E+ GE P P + + + L L CL EP+ RP+ + Sbjct 209 AIELA-KGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKE 267 Query 862 ILRDLTRLQP 871 +L+ ++ Sbjct 268 LLKHKFIIRN 277 >sp|Q9LDS6|CRK32_ARATH Putative cysteine-rich receptor-like protein kinase 32 OS=Arabidopsis thaliana OX=3702 GN=CRK32 PE=3 SV=1 Length=656 Score = 242 bits (618), Expect = 6e-67, Method: Composition-based stats. Identities = 74/329 (22%), Positives = 120/329 (36%), Gaps = 26/329 (8%) Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919 R + L+P D+ + + LG+G FG+V Sbjct 284 RKRRQSYKTLKPKTDDDMTSPQSLQFDFMTLEAATDKFSRNNKLGKGGFGEVYKGMLPNE 343 Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979 VAVK L ++ G Q +K E+ I+ L H+++++ G C ++ E+ LV E Sbjct 344 -----TEVAVKRLSSNSG-QGTQEFKNEVVIVAKLQHKNLVRLLGFCLERDEQ--ILVYE 395 Query 980 YVPLGSLRDYL------------PRHSIGLAQLLLFAQQICEGMAYLHAQH---YIHRDL 1024 +VP SL +L + + + I G+ YLH IHRD+ Sbjct 396 FVPNKSLNYFLFGNKQKHLLDPTKKSQLDWKRRYNIIGGITRGLLYLHQDSRLTIIHRDI 455 Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084 A N+LLD D KI DFG+A+ R + PE + +F SDV Sbjct 456 KASNILLDADMNPKIADFGMARNFRVDQTEDNTRR-VVGTFGYMPPEYVTHGQFSTKSDV 514 Query 1085 WSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 +SFGV + E++ S L+ +L++ + Sbjct 515 YSFGVLILEIVCGKKNSSFYKIDDSGGNLVTHVWRLWNNDSPLDLIDPAIEESCDNDKVI 574 Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKT 1171 H+ C + RP + +L Sbjct 575 RCIHIGLLCVQETPVDRPEMSTIFQMLTN 603 Score = 236 bits (603), Expect = 5e-65, Method: Composition-based stats. Identities = 58/334 (17%), Positives = 107/334 (32%), Gaps = 72/334 (22%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 SP++L + ++ + LG+G VY+G L Sbjct 302 TSPQSLQF-DFMTLEAATDKFSRNNKLGKGGFGEVYKGML-------------------- 340 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 E V +K L + F +++++ H +L + G C+ E I+V E Sbjct 341 -----PNETEVAVKRLSSNSGQGTQEFKNEVVIVAKLQHKNLVRLLGFCLERDEQILVYE 395 Query 689 YVEHGPLDVWLRRE----------RGHVPMAWKMVVAQQLASALSYLENKN---LVHGNV 735 +V + L+ +L + + + + + L YL + ++H ++ Sbjct 396 FVPNKSLNYFLFGNKQKHLLDPTKKSQLDWKRRYNIIGGITRGLLYLHQDSRLTIIHRDI 455 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGAN 789 NILL K++D G+ + V ++ PE + G Sbjct 456 KASNILLD-------ADMNPKIADFGMARNFRVDQTEDNTRRVVGTFGYMPPEYVTHG-- 506 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP---------- 839 ST D + FG +LEI + + + RL P Sbjct 507 QFSTKSDVYSFGVLILEIVCGKKNSSFYKIDDSGGNLVTHVWRLWNNDSPLDLIDPAIEE 566 Query 840 --------QLATLTSQCLTYEPTQRPSFRTILRD 865 + + C+ P RP TI + Sbjct 567 SCDNDKVIRCIHIGLLCVQETPVDRPEMSTIFQM 600 >sp|Q8R4K2|IRAK4_MOUSE Interleukin-1 receptor-associated kinase 4 OS=Mus musculus OX=10090 GN=Irak4 PE=1 SV=1 Length=459 Score = 236 bits (603), Expect = 6e-67, Method: Composition-based stats. Identities = 82/357 (23%), Positives = 133/357 (37%), Gaps = 28/357 (8%) Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR----------LQPHNLADVLTVNP 882 LP +A C + T + ++ + Sbjct 112 LPPREAATVAQTHGPCQEKDRTSVMPMPKLEHSCEPPDSSSPDNRSVESSDTRFHSFSFH 171 Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD---CGPQ 939 + + + +GEG FG V C + T +VAVK L A + Sbjct 172 ELKSITNNFDEQPASAGGNRMGEGGFGVVYKGCVNNT------IVAVKKLGAMVEISTEE 225 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSI 995 + + QEI ++ T HE++++ G D +L LV Y+P GSL D L + Sbjct 226 LKQQFDQEIKVMATCQHENLVELLGFSSDSD--NLCLVYAYMPNGSLLDRLSCLDGTPPL 283 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 AQ G+ +LH H+IHRD+ + N+LLD D KI DFGLA+A + Sbjct 284 SWHTRCKVAQGTANGIRFLHENHHIHRDIKSANILLDKDFTAKISDFGLARASARLAQTV 343 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 + + APE L+ SD++SFGV L EL+T + L L Sbjct 344 MTSRIVGTTA-YMAPEALRGE-ITPKSDIYSFGVVLLELITGLAAVDENREPQLLLDIKE 401 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + + + + + P +Y C + + RP + +L+ + Sbjct 402 EIEDEEKTIEDYTDEKMSDADPASV-EAMYSAASQCLHEKKNRRPDIAKVQQLLQEM 457 Score = 206 bits (525), Expect = 2e-56, Method: Composition-based stats. Identities = 82/459 (18%), Positives = 145/459 (32%), Gaps = 110/459 (24%) Query 485 LTVAQRSQAPDG-MQSLRLRKFPIEQQDGAF----VLEGWGRSFPSVRELGAALQGCLL- 538 L VA + + D +R+F Q G +L WG + +V +L L L Sbjct 35 LAVAIKKPSGDDRYNQFHIRRFEALLQTGKSPTCELLFDWGTTNCTVGDLVDLLVQIELF 94 Query 539 --------------------RAGDDCFSLRRCC--------LPQPGETSNLIIMRGARAS 570 R C +P P + + Sbjct 95 APATLLLPDAVPQTVKSLPPREAATVAQTHGPCQEKDRTSVMPMPKLEHSCEPPDSSSPD 154 Query 571 PRTLNLSQLSFHRVDQKEITQL-------------SHLGQGTRTNVYEGRLRVEGSGDPE 617 R++ S FH E+ + + +G+G VY+G + Sbjct 155 NRSVESSDTRFHSFSFHELKSITNNFDEQPASAGGNRMGEGGFGVVYKGCV--------- 205 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDP----SHHDIALAFYETASLMSQVSHTHLAFV 673 V +K L S ++ F + +M+ H +L + Sbjct 206 -----------------NNTIVAVKKLGAMVEISTEELKQQFDQEIKVMATCQHENLVEL 248 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNLV 731 G +V Y+ +G L L G P++W + VAQ A+ + +L + + Sbjct 249 LGFSSDSDNLCLVYAYMPNGSLLDRLSCLDGTPPLSWHTRCKVAQGTANGIRFLHENHHI 308 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA------LSREERVERIPWLAPECLP 785 H ++ NILL + K+SD G+ + + V ++APE L Sbjct 309 HRDIKSANILLDK-------DFTAKISDFGLARASARLAQTVMTSRIVGTTAYMAPEALR 361 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ----- 840 G ++ D + FG LLE+ A ++R P + + Sbjct 362 G---EITPKSDIYSFGVVLLELITGLAAVDENREPQLLLDIKEEIEDEEKTIEDYTDEKM 418 Query 841 ----------LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + SQCL + +RP + + L + Sbjct 419 SDADPASVEAMYSAASQCLHEKKNRRPDIAKVQQLLQEM 457 >sp|Q54IP4|SHKB_DICDI Dual specificity protein kinase shkB OS=Dictyostelium discoideum OX=44689 GN=shkB PE=3 SV=1 Length=653 Score = 242 bits (618), Expect = 6e-67, Method: Composition-based stats. Identities = 74/284 (26%), Positives = 129/284 (45%), Gaps = 30/284 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH-RSGWKQEIDILRTLY 955 + LG G FG V G+ VA+K L ++ + +K+E+ ++ L Sbjct 174 YNREAKLGSGAFGSVYKGIVR------GKEVAIKKLTQTVFEENTMNEFKKEVSLMAKLR 227 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEG 1010 + H++ + G C + L +V E +P GS+ L I + +L A+ G Sbjct 228 NPHLLLFMGACT--APEDLSIVTELMPKGSVHSLLRAKEDTSDFITFKRAILIARDTVLG 285 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 M +LHA + +H DL N+L+D + +VK+ DFGL+K + + + + G + AP Sbjct 286 MTWLHASNILHLDLKPANLLVDQNWVVKVADFGLSKYMKPDSKDKLLGQAG--SPLYMAP 343 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E L + DV+SF + L+ELLT + + + +L + ++ + Sbjct 344 EMLVNQPYDGKVDVFSFSILLWELLTKQEPYNKLYSSYPQL------------VEGVVNK 391 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP--ILKTV 1172 R PD P + L+ CW+ S RP+F + IL+T+ Sbjct 392 KNRPIIPDYFPTRLKDLLARCWDHYPSRRPSFAEISKQRILETI 435 Score = 211 bits (537), Expect = 3e-56, Method: Composition-based stats. Identities = 64/331 (19%), Positives = 128/331 (39%), Gaps = 61/331 (18%) Query 562 IIMRGARASPRTLNLSQLSF----------HRVDQKEITQLS--HLGQGTRTNVYEGRLR 609 +I+ G+ T +S S +D+ EI+ LG G +VY+G +R Sbjct 135 VILNGSLTEDSTSTISPDSTKNRDEEEIIRWEIDRNEISYNREAKLGSGAFGSVYKGIVR 194 Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSH 667 + V +K L + + F + SLM+++ + Sbjct 195 GK--------------------------EVAIKKLTQTVFEENTMNEFKKEVSLMAKLRN 228 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH---VPMAWKMVVAQQLASALSY 724 HL G C + +VTE + G + LR + + +++A+ +++ Sbjct 229 PHLLLFMGACTAPEDLSIVTELMPKGSVHSLLRAKEDTSDFITFKRAILIARDTVLGMTW 288 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIPWL 779 L N++H ++ N+L+ + + +K++D G+ + + ++ Sbjct 289 LHASNILHLDLKPANLLVDQ-------NWVVKVADFGLSKYMKPDSKDKLLGQAGSPLYM 341 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS--PSEKEHFYQRQHR--LPE 835 APE L +D + F L E+ E + S P E +++R +P+ Sbjct 342 APEMLVN--QPYDGKVDVFSFSILLWELLTKQEPYNKLYSSYPQLVEGVVNKKNRPIIPD 399 Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 +L L ++C + P++RPSF I + Sbjct 400 YFPTRLKDLLARCWDHYPSRRPSFAEISKQR 430 >sp|Q8RZV7|MSP1_ORYSJ Leucine-rich repeat receptor protein kinase MSP1 OS=Oryza sativa subsp. japonica OX=39947 GN=MSP1 PE=1 SV=1 Length=1294 Score = 251 bits (641), Expect = 6e-67, Method: Composition-based stats. Identities = 77/298 (26%), Positives = 121/298 (41%), Gaps = 25/298 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G+G FG V G VA+K L Q + E++ + + H +++ Sbjct 1006 HIIGDGGFGTVYKAALPE-----GRRVAIKRLHGGHQFQGDREFLAEMETIGKVKHPNLV 1060 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLH 1015 G C E+ L+ EY+ GSL +L + +G L G+A+LH Sbjct 1061 PLLGYCVCGDER--FLIYEYMENGSLEMWLRNRADALEALGWPDRLKICLGSARGLAFLH 1118 Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 H IHRD+ + N+LLD + ++ DFGLA+ + + V D + PE Sbjct 1119 HGFVPHIIHRDMKSSNILLDENFEPRVSDFGLARIISACETH--VSTDIAGTFGYIPPEY 1176 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 K DV+SFGV + ELLT Q L+G + + + EL + Sbjct 1177 GLTMKSTTKGDVYSFGVVMLELLTGRPPTGQEEVQGGGNLVGWVRWMIARGKQNELFDPC 1236 Query 1132 ERLPRPDKCPCEVYH---LMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 LP ++ + ++C E RPT ++ LK H G P V +V Sbjct 1237 --LPVSSVWREQMARVLAIARDCTADEPFKRPTMLEVVKGLKMTHGMECG--PLVVTV 1290 Score = 218 bits (556), Expect = 1e-56, Method: Composition-based stats. Identities = 71/390 (18%), Positives = 132/390 (34%), Gaps = 75/390 (19%) Query 525 SVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV 584 + L L+ L+R+ F TS ++ P ++NL+ + Sbjct 929 VLVLLAVYLRRKLVRSRPLAFESASKAKATVEPTSTDELLGKKSREPLSINLATFEHALL 988 Query 585 ---------DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 + +++ +G G VY+ L Sbjct 989 RVTADDILKATENFSKVHIIGDGGFGTVYKAALPEGR----------------------- 1025 Query 636 ELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 RV +K L H F + +V H +L + G CV G E ++ EY+E+G Sbjct 1026 --RVAIKRLHGGHQFQGDREFLAEMETIGKVKHPNLVPLLGYCVCGDERFLIYEYMENGS 1083 Query 695 LDVWLRRERGHVP---MAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLA 748 L++WLR + ++ + A L++L + +++H ++ NILL Sbjct 1084 LEMWLRNRADALEALGWPDRLKICLGSARGLAFLHHGFVPHIIHRDMKSSNILLDE---- 1139 Query 749 EGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 + ++SD G+ + E V ++ PE G +T D + FG Sbjct 1140 ---NFEPRVSDFGLARIISACETHVSTDIAGTFGYIPPEY--GLTMKSTTKGDVYSFGVV 1194 Query 804 LLEICFDGEAPLQSRSPS---------EKEHFYQRQHRLPEPSCP----------QLATL 844 +LE+ G P +Q+ L +P P ++ + Sbjct 1195 MLELL-TGRPPTGQEEVQGGGNLVGWVRWMIARGKQNELFDPCLPVSSVWREQMARVLAI 1253 Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 C EP +RP+ +++ L Sbjct 1254 ARDCTADEPFKRPTMLEVVKGLKMTHGMEC 1283 >sp|Q9FN92|Y5597_ARATH Probable receptor-like protein kinase At5g59700 OS=Arabidopsis thaliana OX=3702 GN=At5g59700 PE=1 SV=1 Length=829 Score = 246 bits (627), Expect = 6e-67, Method: Composition-based stats. Identities = 76/292 (26%), Positives = 126/292 (43%), Gaps = 23/292 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FGKV G VAVK Q + ++ EI++L H H++ Sbjct 488 IGVGGFGKVYKGEL-----HDGTKVAVKRANPK-SQQGLAEFRTEIEMLSQFRHRHLVSL 541 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHA--- 1016 G C++ E + LV EY+ G+L+ +L S+ Q L G+ YLH Sbjct 542 IGYCDENNE--MILVYEYMENGTLKSHLYGSGLLSLSWKQRLEICIGSARGLHYLHTGDA 599 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + IHRD+ + N+LLD + + K+ DFGL+K PE + + V + PE + Sbjct 600 KPVIHRDVKSANILLDENLMAKVADFGLSKTGPEIDQTH-VSTAVKGSFGYLDPEYFRRQ 658 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR---LTELLERGER 1133 + SDV+SFGV ++E+L C PT E++ +A+ M + L +++ R Sbjct 659 QLTEKSDVYSFGVVMFEVL--CARPVIDPTLTREMVNLAEWAMKWQKKGQLEHIIDPSLR 716 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK---TVHEKYQGQAPS 1182 + + C RP+ +++ L+ + E P Sbjct 717 GKIRPDSLRKFGETGEKCLADYGVDRPSMGDVLWNLEYALQLQEAVVDGDPE 768 Score = 219 bits (558), Expect = 6e-58, Method: Composition-based stats. Identities = 57/273 (21%), Positives = 94/273 (34%), Gaps = 51/273 (19%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + +G G VY+G L +V +K Sbjct 478 ATNSFDENRAIGVGGFGKVYKGELHDG-------------------------TKVAVKRA 512 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 +P F ++SQ H HL + G C E I+V EY+E+G L L G Sbjct 513 NPKSQQGLAEFRTEIEMLSQFRHRHLVSLIGYCDENNEMILVYEYMENGTLKSHLYGS-G 571 Query 705 HVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + ++W ++ + A L YL K ++H +V NILL + K++D Sbjct 572 LLSLSWKQRLEICIGSARGLHYLHTGDAKPVIHRDVKSANILLDE-------NLMAKVAD 624 Query 760 PGVGL-GALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ G + V +L PE L+ D + FG + E+ Sbjct 625 FGLSKTGPEIDQTHVSTAVKGSFGYLDPEYFR--RQQLTEKSDVYSFGVVMFEVLCARPV 682 Query 814 PLQSRSPS-----EKEHFYQRQHRLPEPSCPQL 841 + + E +Q++ +L P L Sbjct 683 IDPTLTREMVNLAEWAMKWQKKGQLEHIIDPSL 715 >sp|O81833|SD11_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase SD1-1 OS=Arabidopsis thaliana OX=3702 GN=SD11 PE=1 SV=1 Length=815 Score = 246 bits (627), Expect = 6e-67, Method: Composition-based stats. Identities = 79/324 (24%), Positives = 126/324 (39%), Gaps = 22/324 (7%) Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916 + I++ + ++ + LG G FG V Sbjct 460 CFRKKIMKRYRGENFRKGIEEEDLDLPIFDRKTISIATDDFSYVNFLGRGGFGPVYKGKL 519 Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976 + G+ +AVK L A+ G Q +K E+ ++ L H ++++ GCC E L Sbjct 520 E-----DGQEIAVKRLSANSG-QGVEEFKNEVKLIAKLQHRNLVRLLGCCIQGEEC--ML 571 Query 977 VMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNV 1029 + EY+P SL ++ + + + + G+ YLH IHRDL A NV Sbjct 572 IYEYMPNKSLDFFIFDERRSTELDWKKRMNIINGVARGILYLHQDSRLRIIHRDLKAGNV 631 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 LLDND KI DFGLAK+ G + + PE + F SDV+SFGV Sbjct 632 LLDNDMNPKISDFGLAKSFG-GDQSESSTNRVVGTYGYMPPEYAIDGHFSVKSDVFSFGV 690 Query 1090 TLYELLTHCDSSQSPP-TKFLELIGIAQGQMTVLRLTELLERGERLP---RPDKCPCEVY 1145 + E++T + L L+G R E+ E P+ Sbjct 691 LVLEIITGKTNRGFRHADHDLNLLGHVWKMWVEDREIEVPEEEWLEETSVIPE--VLRCI 748 Query 1146 HLMKNCWETEASFRPTFENLIPIL 1169 H+ C + + RPT +++ + Sbjct 749 HVALLCVQQKPEDRPTMASVVLMF 772 Score = 236 bits (602), Expect = 1e-63, Method: Composition-based stats. Identities = 58/371 (16%), Positives = 119/371 (32%), Gaps = 65/371 (18%) Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 +G L + + + + ++ LG+G VY+G+L Sbjct 476 KGIEEEDLDLPIFDRKTISIATDDFSYVNFLGRGGFGPVYKGKLEDGQ------------ 523 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 + +K L + F L++++ H +L + G C++G E + Sbjct 524 -------------EIAVKRLSANSGQGVEEFKNEVKLIAKLQHRNLVRLLGCCIQGEECM 570 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRN 739 ++ EY+ + LD ++ ER + W +M + +A + YL ++H ++ N Sbjct 571 LIYEYMPNKSLDFFIFDERRSTELDWKKRMNIINGVARGILYLHQDSRLRIIHRDLKAGN 630 Query 740 ILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLST 793 +LL K+SD G+ S V ++ PE G S Sbjct 631 VLLDN-------DMNPKISDFGLAKSFGGDQSESSTNRVVGTYGYMPPEYAIDG--HFSV 681 Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS---------------- 837 D + FG +LEI G+ R + ++ Sbjct 682 KSDVFSFGVLVLEII-TGKTNRGFRHADHDLNLLGHVWKMWVEDREIEVPEEEWLEETSV 740 Query 838 CPQLAT---LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894 P++ + C+ +P RP+ +++ + D + Sbjct 741 IPEVLRCIHVALLCVQQKPEDRPTMASVVLMFGSDSSLPHPTQPGFFTNRNVPDISSSLS 800 Query 895 RYLKKIRDLGE 905 + + Sbjct 801 LRSQNEVSITM 811 >sp|Q54TH6|Y9863_DICDI Probable serine/threonine-protein kinase DDB_G0281745 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0281745 PE=3 SV=1 Length=597 Score = 241 bits (614), Expect = 6e-67, Method: Composition-based stats. Identities = 70/297 (24%), Positives = 125/297 (42%), Gaps = 32/297 (11%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 + +K ++G G +G VSL + G VA+K L + + ++E Sbjct 325 MWNIDYKELKFVGNEIGSGKYGSVSLGYWL------GTPVAIKKL-HENNEETEILVQRE 377 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQ 1005 + IL+ + H I+++ G ++ ++ + ++ E++ G L D L + + L + Sbjct 378 LQILKEIRHPQIVQFLGVSRNEKDE-IHIITEFMDGGDLFDALIFGDIPLTWKEKLRISL 436 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 I + +LHA+ +HRDL ++N+LL +R K+ D GLA+ E R Sbjct 437 DIAQSCRFLHARGILHRDLKSQNILLSTNRRAKLCDLGLARMF---EERINKRYTCVGTE 493 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 W APE + + A DV+SFG+ L E++T + P + A + Sbjct 494 IWMAPEVCLDQSYSTAVDVFSFGIVLVEIITEKIPDERFPQHRFQFDAPAFLKKV----- 548 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182 P +CP + L +C + RP+F I +L T+ Y Sbjct 549 -----------PKECPPDFSKLCVDCTKYNPKERPSF---IKVLDTIQNIYDSLPDD 591 Score = 204 bits (520), Expect = 1e-54, Method: Composition-based stats. Identities = 61/318 (19%), Positives = 115/318 (36%), Gaps = 41/318 (13%) Query 559 SNLIIMRGARASPRTLNLSQLSFHRVDQKEITQ-LSHLGQGTRTNVYEGRLRVEGSGDPE 617 S+L+ + +D KE+ + +G G +V G Sbjct 303 SSLVEKSPRNNESTATTATTKDMWNIDYKELKFVGNEIGSGKYGSVSLGYWLG------- 355 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 V +K L ++ + + ++ ++ H + GV Sbjct 356 -------------------TPVAIKKLHENNEETEILVQRELQILKEIRHPQIVQFLGVS 396 Query 678 V-RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736 E ++TE+++ G L L + K+ ++ +A + +L + ++H ++ Sbjct 397 RNEKDEIHIITEFMDGGDLFDALIFGDIPLTWKEKLRISLDIAQSCRFLHARGILHRDLK 456 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLS 792 +NILL+ T+ KL D G+ R V W+APE S S Sbjct 457 SQNILLS-------TNRRAKLCDLGLARMFEERINKRYTCVGTEIWMAPEVCLD--QSYS 507 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYE 852 TA+D + FG L+EI + + + ++P+ P + L C Y Sbjct 508 TAVDVFSFGIVLVEIITEKIPDERFPQHRFQFDAPAFLKKVPKECPPDFSKLCVDCTKYN 567 Query 853 PTQRPSFRTILRDLTRLQ 870 P +RPSF +L + + Sbjct 568 PKERPSFIKVLDTIQNIY 585 >sp|Q9LX66|HERK_ARATH Receptor-like protein kinase HERK 1 OS=Arabidopsis thaliana OX=3702 GN=HERK1 PE=1 SV=1 Length=830 Score = 246 bits (627), Expect = 7e-67, Method: Composition-based stats. Identities = 77/304 (25%), Positives = 133/304 (44%), Gaps = 23/304 (8%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 + R++G G FGKV G VAVK Q + ++ EI++L Sbjct 483 NNFDESRNIGVGGFGKVYKGEL-----NDGTKVAVKRGNPK-SQQGLAEFRTEIEMLSQF 536 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGM 1011 H H++ G C++ E + L+ EY+ G+++ +L S+ Q L G+ Sbjct 537 RHRHLVSLIGYCDENNE--MILIYEYMENGTVKSHLYGSGLPSLTWKQRLEICIGAARGL 594 Query 1012 AYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 YLH ++ IHRD+ + N+LLD + + K+ DFGL+K PE + + V + Sbjct 595 HYLHTGDSKPVIHRDVKSANILLDENFMAKVADFGLSKTGPELDQTH-VSTAVKGSFGYL 653 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR---LT 1125 PE + + SDV+SFGV L+E+L C PT E++ +A+ M + L Sbjct 654 DPEYFRRQQLTDKSDVYSFGVVLFEVL--CARPVIDPTLPREMVNLAEWAMKWQKKGQLD 711 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK---TVHEKYQGQAPS 1182 +++++ R + + C RP+ +++ L+ + E P Sbjct 712 QIIDQSLRGNIRPDSLRKFAETGEKCLADYGVDRPSMGDVLWNLEYALQLQEAVIDGEPE 771 Query 1183 VFSV 1186 S Sbjct 772 DNST 775 Score = 220 bits (561), Expect = 3e-58, Method: Composition-based stats. Identities = 54/272 (20%), Positives = 94/272 (35%), Gaps = 49/272 (18%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + ++G G VY+G L +V +K Sbjct 481 ATNNFDESRNIGVGGFGKVYKGELNDG-------------------------TKVAVKRG 515 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER- 703 +P F ++SQ H HL + G C E I++ EY+E+G + L Sbjct 516 NPKSQQGLAEFRTEIEMLSQFRHRHLVSLIGYCDENNEMILIYEYMENGTVKSHLYGSGL 575 Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + ++ + A L YL +K ++H +V NILL + K++D Sbjct 576 PSLTWKQRLEICIGAARGLHYLHTGDSKPVIHRDVKSANILLDE-------NFMAKVADF 628 Query 761 GVGL-GALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA- 813 G+ G + V +L PE L+ D + FG L E+ Sbjct 629 GLSKTGPELDQTHVSTAVKGSFGYLDPEYFR--RQQLTDKSDVYSFGVVLFEVLCARPVI 686 Query 814 ----PLQSRSPSEKEHFYQRQHRLPEPSCPQL 841 P + + +E +Q++ +L + L Sbjct 687 DPTLPREMVNLAEWAMKWQKKGQLDQIIDQSL 718 >sp|C0LGT5|Y5169_ARATH Probable LRR receptor-like serine/threonine-protein kinase At5g16900 OS=Arabidopsis thaliana OX=3702 GN=At5g16900 PE=1 SV=1 Length=866 Score = 246 bits (629), Expect = 7e-67, Method: Composition-based stats. Identities = 67/287 (23%), Positives = 124/287 (43%), Gaps = 17/287 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R +GEG FG V E VAVK L ++ +K E+++L + Sbjct 571 MTNNFERVIGEGGFGVVYHGYL-----NDSEQVAVKVLSPSSSQGYKE-FKAEVELLLRV 624 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEG 1010 +H +++ G C++Q L L+ EY+ G L+ +L + L A + G Sbjct 625 HHINLVSLVGYCDEQAH--LALIYEYMANGDLKSHLSGKHGDCVLKWENRLSIAVETALG 682 Query 1011 MAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH+ +HRD+ + N+LLD K+ DFGL+++ G E + +P + Sbjct 683 LEYLHSGCKPLMVHRDVKSMNILLDEHFQAKLADFGLSRSFSVGEESHVSTGVVGTP-GY 741 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 PE + Y+ SDV+SFG+ L E++T+ + + + + +T ++ + Sbjct 742 LDPEYYRTYRLTEKSDVYSFGIVLLEIITNQPVLEQA-NENRHIAERVRTMLTRSDISTI 800 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 ++ + L +C + RP +++ LK + Sbjct 801 VDPNLIGEYDSGSVRKALKLAMSCVDPSPVARPDMSHVVQELKQCIK 847 Score = 211 bits (536), Expect = 6e-55, Method: Composition-based stats. Identities = 74/331 (22%), Positives = 115/331 (35%), Gaps = 66/331 (20%) Query 571 PRTLNLS-QLSFHRVDQKEI-----TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 P NLS + R+ EI +G+G VY G L Sbjct 549 PSRANLSLENKKRRITYSEILLMTNNFERVIGEGGFGVVYHGYLNDSE------------ 596 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 +V +KVL PS F L+ +V H +L + G C Sbjct 597 -------------QVAVKVLSPSSSQGYKEFKAEVELLLRVHHINLVSLVGYCDEQAHLA 643 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRN 739 ++ EY+ +G L L + G + W ++ +A + A L YL + +VH +V N Sbjct 644 LIYEYMANGDLKSHLSGKHGDCVLKWENRLSIAVETALGLEYLHSGCKPLMVHRDVKSMN 703 Query 740 ILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLST 793 ILL KL+D G+ EE V +L PE L+ Sbjct 704 ILLDE-------HFQAKLADFGLSRSFSVGEESHVSTGVVGTPGYLDPEYYRT--YRLTE 754 Query 794 AMDKWGFGATLLEICFDG---EAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--------- 841 D + FG LLEI + E ++R +E+ + + P L Sbjct 755 KSDVYSFGIVLLEIITNQPVLEQANENRHIAERVRTMLTRSDISTIVDPNLIGEYDSGSV 814 Query 842 ---ATLTSQCLTYEPTQRPSFRTILRDLTRL 869 L C+ P RP ++++L + Sbjct 815 RKALKLAMSCVDPSPVARPDMSHVVQELKQC 845 >sp|A7J1T2|M313A_XENLA Mitogen-activated protein kinase kinase kinase 13-A OS=Xenopus laevis OX=8355 GN=map3k13-a PE=2 SV=1 Length=961 Score = 248 bits (632), Expect = 8e-67, Method: Composition-based stats. Identities = 84/301 (28%), Positives = 125/301 (42%), Gaps = 35/301 (12%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + + + + + + +++ LG G G V L + GE VA+K Sbjct 143 WNIIGKAYSTDYKLQQQETWEVPFEEISELQWLGSGAQGAVFLGKFR------GEEVAIK 196 Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 + R + +I LR L H +II +KG C L+MEY G L + L Sbjct 197 KV--------REQKETDIKHLRKLKHPNIIAFKGVCTQA--PCYCLIMEYCAHGQLYEVL 246 Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 + L+ ++ I GM YLH IHRDL + NVL+ + VKI DFG +K + Sbjct 247 RAGRKVSPRLLVDWSNGIASGMNYLHLHKIIHRDLKSPNVLVTHTDTVKISDFGTSKELS 306 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 + + V W APE ++ D+WSFGV L+ELLT P K + Sbjct 307 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVLLWELLTG-----EIPYKDV 357 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + I G + LP P CP LMK W ++ RP+F ++ L Sbjct 358 DSSAIIWGVGSN---------SLHLPVPSTCPDGFKILMKQTWHSKPRNRPSFRQILMHL 408 Query 1170 K 1170 Sbjct 409 D 409 Score = 218 bits (554), Expect = 7e-57, Method: Composition-based stats. Identities = 67/305 (22%), Positives = 110/305 (36%), Gaps = 50/305 (16%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 +A L Q V +EI++L LG G + V+ G+ R E Sbjct 147 GKAYSTDYKLQQQETWEVPFEEISELQWLGSGAQGAVFLGKFRGE--------------- 191 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 V +K + + ++ H ++ GVC + P ++ Sbjct 192 -----------EVAIKKVREQKE-------TDIKHLRKLKHPNIIAFKGVCTQAPCYCLI 233 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 EY HG L LR R P + + +AS ++YL ++H ++ N+L+ Sbjct 234 MEYCAHGQLYEVLRAGRKVSP-RLLVDWSNGIASGMNYLHLHKIIHRDLKSPNVLVTH-- 290 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 + +K+SD G + ++ + W+APE + +S +D W FG Sbjct 291 -----TDTVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVL 343 Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 L E+ GE P + S +P L Q +P RPSFR Sbjct 344 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWHSKPRNRPSFR 402 Query 861 TILRD 865 IL Sbjct 403 QILMH 407 >sp|Q5Z6X0|CIPKP_ORYSJ CBL-interacting protein kinase 25 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK25 PE=2 SV=1 Length=514 Score = 238 bits (607), Expect = 8e-67, Method: Composition-based stats. Identities = 68/275 (25%), Positives = 119/275 (43%), Gaps = 32/275 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960 +GEG+F KV L + TGE VA+K + + K+EI +++ L H +++ Sbjct 27 VGEGNFAKVYLGRHRA----TGEEVAIKVMDKEKLVRLGATELIKREIAVMQRLRHPNVV 82 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYL 1014 + ++ + + +VMEYV G+L Y R + + F QQ+ +AY Sbjct 83 RIHEVMANK--RRICVVMEYVRGGALYRYFRRGPSGGAAGLREHEARRFFQQLVSAVAYC 140 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H++ HRD+ N+L+D +K+ DFGL+ ++ +P+F APE K Sbjct 141 HSRGVFHRDIKLDNLLVDEQGNLKVADFGLSALADMERREAHLQTVCGTPLF-LAPEVFK 199 Query 1075 EYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + +DVW+ GV LY LLT V RL L+ + + Sbjct 200 RRGYDGAKADVWACGVVLYVLLTGRKPF---------------PDEHVSRLYRLIGQN-Q 243 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 P ++ L++ + + R T ++ + Sbjct 244 FQCPPSFSPDLARLVRRLLQPDPDRRITIPEIMEM 278 Score = 184 bits (467), Expect = 3e-48, Method: Composition-based stats. Identities = 56/298 (19%), Positives = 95/298 (32%), Gaps = 45/298 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + + +G+G VY GR R G V +KV Sbjct 16 MTTERYEFGPLVGEGNFAKVYLGRHRATGE------------------------EVAIKV 51 Query 644 LDPSHH---DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 +D ++M ++ H ++ +H V +V EYV G L + R Sbjct 52 MDKEKLVRLGATELIKREIAVMQRLRHPNVVRIHEVMANKRRICVVMEYVRGGALYRYFR 111 Query 701 RERG----HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 R + QQL SA++Y ++ + H ++ N+L+ G +K Sbjct 112 RGPSGGAAGLREHEARRFFQQLVSAVAYCHSRGVFHRDIKLDNLLVDEQG-------NLK 164 Query 757 LSDPGVG------LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 ++D G+ + +LAPE D W G L + Sbjct 165 VADFGLSALADMERREAHLQTVCGTPLFLAPEVFKRRGYD-GAKADVWACGVVLYVLLTG 223 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + Q Q + P P LA L + L +P +R + I+ Sbjct 224 RKPFPDEHVSRLYRLIGQNQFQCPPSFSPDLARLVRRLLQPDPDRRITIPEIMEMRWF 281 >sp|O65405|CRK28_ARATH Cysteine-rich receptor-like protein kinase 28 OS=Arabidopsis thaliana OX=3702 GN=CRK28 PE=3 SV=2 Length=683 Score = 243 bits (619), Expect = 8e-67, Method: Composition-based stats. Identities = 77/338 (23%), Positives = 123/338 (36%), Gaps = 28/338 (8%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 + L + L + + +LG G F Sbjct 313 WKKNKSVGRVKGNKHNLLLLVIVILLQKDEFSDSLVVDFETLKAATDNFSPENELGRGGF 372 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968 G V + G+ +AVK L G Q S +K EI +L L H ++++ G C + Sbjct 373 GSVYKGVFSG-----GQEIAVKRLSCTSG-QGDSEFKNEILLLAKLQHRNLVRLLGFCIE 426 Query 969 QGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIH 1021 E+ LV E++ SL +++ R + + G+ YLH IH Sbjct 427 GQER--ILVYEFIKNASLDNFIFDLKKRQLLDWGVRYKMIGGVARGLLYLHEDSRYRIIH 484 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGH-EYYRVREDGDSPVFWYAPECLKEYKFYY 1080 RDL A N+LLD + KI DFGLAK +R + APE +F Sbjct 485 RDLKASNILLDQEMNPKIADFGLAKLYDTDQTSTHRFTSKIAGTYGYMAPEYAIYGQFSV 544 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR-------LTELLERGER 1133 +DV+SFGV + E++T ++ E + R + L G R Sbjct 545 KTDVFSFGVLVIEIITGKGNNNGRSNDDEEAENLLSWVWRCWREDIILSVIDPSLTTGSR 604 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 H+ C + + RPT +++ +L + Sbjct 605 SEI-----LRCIHIGLLCVQESPASRPTMDSVALMLNS 637 Score = 229 bits (584), Expect = 3e-62, Method: Composition-based stats. Identities = 58/358 (16%), Positives = 109/358 (30%), Gaps = 65/358 (18%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 + + + LG+G +VY+G Sbjct 350 DFETLKAATDNFSPENELGRGGFGSVYKGVFSGGQ------------------------- 384 Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 + +K L + F L++++ H +L + G C+ G E I+V E++++ LD Sbjct 385 EIAVKRLSCTSGQGDSEFKNEILLLAKLQHRNLVRLLGFCIEGQERILVYEFIKNASLDN 444 Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752 ++ + + W + + +A L YL ++H ++ NILL + Sbjct 445 FIFDLKKRQLLDWGVRYKMIGGVARGLLYLHEDSRYRIIHRDLKASNILLDQE------- 497 Query 753 PFIKLSDPGVGLGALSREERV--------ERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 K++D G+ + + ++APE G S D + FG + Sbjct 498 MNPKIADFGLAKLYDTDQTSTHRFTSKIAGTYGYMAPEYAIYG--QFSVKTDVFSFGVLV 555 Query 805 LEICF-DGEAPLQSRSPSEKEHFYQRQHRLPEPS------CPQLAT-----------LTS 846 +EI G +S E E+ R P L T + Sbjct 556 IEIITGKGNNNGRSNDDEEAENLLSWVWRCWREDIILSVIDPSLTTGSRSEILRCIHIGL 615 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 C+ P RP+ ++ L + L Sbjct 616 LCVQESPASRPTMDSVALMLNSYSYTLPTPSRPAFALESVMPSMNVSSSTEPLLMSLN 673 >sp|Q6Z4U4|BAK1_ORYSJ LRR receptor kinase BAK1 OS=Oryza sativa subsp. japonica OX=39947 GN=BAK1 PE=1 SV=1 Length=624 Score = 241 bits (615), Expect = 8e-67, Method: Composition-based stats. Identities = 73/324 (23%), Positives = 123/324 (38%), Gaps = 20/324 (6%) Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917 R + +V + LG G FGKV Sbjct 262 RRRKPQEHFFDVPAEEDPEVHLGQLKRFSLRELQVATDTFSNKNILGRGGFGKVYKGRL- 320 Query 918 PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLV 977 G +VAVK LK + P ++ E++++ H ++++ +G C E+ LV Sbjct 321 ----ADGSLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTER--LLV 374 Query 978 MEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNV 1029 Y+ GS+ L + A G++YLH IHRD+ A N+ Sbjct 375 YPYMANGSVASRLRERPPSEPPLDWRTRRRIALGSARGLSYLHDHCDPKIIHRDVKAANI 434 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 LLD D +GDFGLAK + + V + APE L K +DV+ +G+ Sbjct 435 LLDEDFEAVVGDFGLAKLMDYKDTH--VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 492 Query 1090 TLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 L EL+T + + + L+ +G + RL L++ + D + Sbjct 493 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKRLEMLVDPDLQSNYIDVEVESLIQ 552 Query 1147 LMKNCWETEASFRPTFENLIPILK 1170 + C + + RP ++ +L+ Sbjct 553 VALLCTQGSPTERPKMAEVVRMLE 576 Score = 198 bits (504), Expect = 3e-52, Method: Composition-based stats. Identities = 71/324 (22%), Positives = 113/324 (35%), Gaps = 67/324 (21%) Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + S V + + LG+G VY+GRL Sbjct 285 QLKRFSLRELQVATDTFSNKNILGRGGFGKVYKGRLADGS-------------------- 324 Query 633 RGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 V +K L L F ++S H +L + G C+ E ++V Y+ Sbjct 325 -----LVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMA 379 Query 692 HGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745 +G + LR R P+ W + +A A LSYL + ++H +V NILL Sbjct 380 NGSVASRLRERPPSEPPLDWRTRRRIALGSARGLSYLHDHCDPKIIHRDVKAANILLDED 439 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800 A + D G+ ++ V I +APE L G + S D +G+ Sbjct 440 FEAV-------VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 490 Query 801 GATLLEICFDGEAPLQSR--SPSEKEHFYQ-----RQHRLPEPSCPQLAT---------- 843 G LLE+ A +R + + ++ RL P L + Sbjct 491 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKRLEMLVDPDLQSNYIDVEVESL 550 Query 844 --LTSQCLTYEPTQRPSFRTILRD 865 + C PT+RP ++R Sbjct 551 IQVALLCTQGSPTERPKMAEVVRM 574 >sp|B8BB68|BAK1_ORYSI LRR receptor kinase BAK1 OS=Oryza sativa subsp. indica OX=39946 GN=BAK1 PE=2 SV=1 Length=624 Score = 241 bits (615), Expect = 8e-67, Method: Composition-based stats. Identities = 73/324 (23%), Positives = 123/324 (38%), Gaps = 20/324 (6%) Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917 R + +V + LG G FGKV Sbjct 262 RRRKPQEHFFDVPAEEDPEVHLGQLKRFSLRELQVATDTFSNKNILGRGGFGKVYKGRL- 320 Query 918 PTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLV 977 G +VAVK LK + P ++ E++++ H ++++ +G C E+ LV Sbjct 321 ----ADGSLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTER--LLV 374 Query 978 MEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNV 1029 Y+ GS+ L + A G++YLH IHRD+ A N+ Sbjct 375 YPYMANGSVASRLRERPPSEPPLDWRTRRRIALGSARGLSYLHDHCDPKIIHRDVKAANI 434 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 LLD D +GDFGLAK + + V + APE L K +DV+ +G+ Sbjct 435 LLDEDFEAVVGDFGLAKLMDYKDTH--VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGI 492 Query 1090 TLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 L EL+T + + + L+ +G + RL L++ + D + Sbjct 493 MLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKRLEMLVDPDLQSNYIDVEVESLIQ 552 Query 1147 LMKNCWETEASFRPTFENLIPILK 1170 + C + + RP ++ +L+ Sbjct 553 VALLCTQGSPTERPKMAEVVRMLE 576 Score = 198 bits (504), Expect = 3e-52, Method: Composition-based stats. Identities = 71/324 (22%), Positives = 113/324 (35%), Gaps = 67/324 (21%) Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + S V + + LG+G VY+GRL Sbjct 285 QLKRFSLRELQVATDTFSNKNILGRGGFGKVYKGRLADGS-------------------- 324 Query 633 RGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 V +K L L F ++S H +L + G C+ E ++V Y+ Sbjct 325 -----LVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMA 379 Query 692 HGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745 +G + LR R P+ W + +A A LSYL + ++H +V NILL Sbjct 380 NGSVASRLRERPPSEPPLDWRTRRRIALGSARGLSYLHDHCDPKIIHRDVKAANILLDED 439 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800 A + D G+ ++ V I +APE L G + S D +G+ Sbjct 440 FEAV-------VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 490 Query 801 GATLLEICFDGEAPLQSR--SPSEKEHFYQ-----RQHRLPEPSCPQLAT---------- 843 G LLE+ A +R + + ++ RL P L + Sbjct 491 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKRLEMLVDPDLQSNYIDVEVESL 550 Query 844 --LTSQCLTYEPTQRPSFRTILRD 865 + C PT+RP ++R Sbjct 551 IQVALLCTQGSPTERPKMAEVVRM 574 >sp|O64777|Y1643_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61430 OS=Arabidopsis thaliana OX=3702 GN=At1g61430 PE=2 SV=2 Length=806 Score = 245 bits (625), Expect = 8e-67, Method: Composition-based stats. Identities = 74/307 (24%), Positives = 120/307 (39%), Gaps = 14/307 (5%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 + LG G FG V G +AVK L + G Q + Sbjct 476 FFEMNAIQTATNNFSLSNKLGPGGFGSVYKA--RNGKLQDGREIAVKRLSSSSG-QGKQE 532 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ 999 + EI ++ L H ++++ GCC + EK L+ ++ SL ++ + + + Sbjct 533 FMNEIVLISKLQHRNLVRVLGCCVEGTEK--LLIYGFLKNKSLDTFVFDARKKLELDWPK 590 Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 + I G+ YLH IHRDL N+LLD KI DFGLA+ +G +Y Sbjct 591 RFEIIEGIARGLLYLHRDSRLRVIHRDLKVSNILLDEKMNPKISDFGLARMF-QGTQYQE 649 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIA 1115 + + +PE F SD++SFGV L E+++ SS S + L+ A Sbjct 650 KTRRVVGTLGYMSPEYAWTGVFSEKSDIYSFGVLLLEIISGKKISSFSYGEEGKALLAYA 709 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 R L++ + C + E + RP L+ +L T + Sbjct 710 WECWCETREVNFLDQALADSSHPSEVGRCVQIGLLCVQHEPADRPNTLELLSMLTTTSDL 769 Query 1176 YQGQAPS 1182 + P+ Sbjct 770 PLPKKPT 776 Score = 220 bits (560), Expect = 2e-58, Method: Composition-based stats. Identities = 68/352 (19%), Positives = 120/352 (34%), Gaps = 60/352 (17%) Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRT-LNLSQLSFHRVDQKEITQLSHLGQGTRT 601 F RC + SN ++ L +++ + + + LG G Sbjct 442 AAFGFWRCRVEHNAHISNDAWRNFLQSQDVPGLEFFEMNAIQTATNNFSLSNKLGPGGFG 501 Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL 661 +VY+ R G + +K L S F L Sbjct 502 SVYKARNGKLQDGR----------------------EIAVKRLSSSSGQGKQEFMNEIVL 539 Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLA 719 +S++ H +L V G CV G E +++ ++++ LD ++ R + + W + + + +A Sbjct 540 ISKLQHRNLVRVLGCCVEGTEKLLIYGFLKNKSLDTFVFDARKKLELDWPKRFEIIEGIA 599 Query 720 SALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREER 772 L YL ++H ++ NILL K+SD G+ + R Sbjct 600 RGLLYLHRDSRLRVIHRDLKVSNILLDEK-------MNPKISDFGLARMFQGTQYQEKTR 652 Query 773 --VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS--------- 821 V + +++PE G S D + FG LLEI + S Sbjct 653 RVVGTLGYMSPEYAWTGV--FSEKSDIYSFGVLLLEIISGKKISSFSYGEEGKALLAYAW 710 Query 822 ----EKEHFYQRQHRLPEPSCP----QLATLTSQCLTYEPTQRPSFRTILRD 865 E L + S P + + C+ +EP RP+ +L Sbjct 711 ECWCETREVNFLDQALADSSHPSEVGRCVQIGLLCVQHEPADRPNTLELLSM 762 >sp|O24527|SIK1_ARATH Serine/threonine-protein kinase 1 OS=Arabidopsis thaliana OX=3702 GN=SIK1 PE=1 SV=1 Length=836 Score = 246 bits (627), Expect = 9e-67, Method: Composition-based stats. Identities = 78/315 (25%), Positives = 130/315 (41%), Gaps = 26/315 (8%) Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915 PS + + + P S + + +LG+G +G V Sbjct 208 DPSSSSSKLHGEDNRKMQQQNSKMSTTSLPDSITREDPTTKYEFLNELGKGSYGSV---- 263 Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 Y + T E+VAVK + G + + EI++L+ H ++++Y G QGE L Sbjct 264 YKARDLKTSEIVAVKVISLTEGEEGYEEIRGEIEMLQQCNHPNVVRYLGSY--QGEDYLW 321 Query 976 LVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033 +VMEY GS+ D + ++ Q+ ++ +G+AYLH+ + +HRD+ N+LL Sbjct 322 IVMEYCGGGSVADLMNVTEEALEEYQIAYICREALKGLAYLHSIYKVHRDIKGGNILLTE 381 Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 VK+GDFG+A + R W APE ++E ++ DVW+ GV+ E Sbjct 382 QGEVKLGDFGVAAQL---TRTMSKRNTFIGTPHWMAPEVIQENRYDGKVDVWALGVSAIE 438 Query 1094 LLTHCDSSQSP-PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152 + S P + L +I I M L +K + + C Sbjct 439 MAEGLPPRSSVHPMRVLFMISIEPAPM--------------LEDKEKWSLVFHDFVAKCL 484 Query 1153 ETEASFRPTFENLIP 1167 E RPT ++ Sbjct 485 TKEPRLRPTAAEMLK 499 Score = 203 bits (517), Expect = 1e-52, Method: Composition-based stats. Identities = 61/333 (18%), Positives = 108/333 (32%), Gaps = 43/333 (13%) Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 M+ + T +L + L+ LG+G+ +VY+ Sbjct 224 MQQQNSKMSTTSLPDSITREDPTTKYEFLNELGKGSYGSVYKA----------------- 266 Query 624 EDPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 RD V +KV+ + ++ Q +H ++ G Sbjct 267 -------RDLKTSEIVAVKVISLTEGEEGYEEIRGEIEMLQQCNHPNVVRYLGSYQGEDY 319 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +V EY G + + + + ++ L+YL + VH ++ G NILL Sbjct 320 LWIVMEYCGGGSVADLMNVTEEALEEYQIAYICREALKGLAYLHSIYKVHRDIKGGNILL 379 Query 743 ARLGLAEGTSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKW 798 G +KL D GV R + W+APE + N +D W Sbjct 380 TEQGE-------VKLGDFGVAAQLTRTMSKRNTFIGTPHWMAPEVIQE--NRYDGKVDVW 430 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP----EPSCPQLATLTSQCLTYEPT 854 G + +E+ +G P S P + E ++CLT EP Sbjct 431 ALGVSAIEMA-EGLPPRSSVHPMRVLFMISIEPAPMLEDKEKWSLVFHDFVAKCLTKEPR 489 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 RP+ +L+ + A ++ + Sbjct 490 LRPTAAEMLKHKFVERCKTGASAMSPKIEKSRQ 522 >sp|Q94F62|BAK1_ARATH BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 OS=Arabidopsis thaliana OX=3702 GN=BAK1 PE=1 SV=2 Length=615 Score = 241 bits (614), Expect = 9e-67, Method: Composition-based stats. Identities = 71/325 (22%), Positives = 125/325 (38%), Gaps = 20/325 (6%) Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916 + + +V + LG G FGKV Sbjct 249 WRRKKPQDHFFDVPAEEDPEVHLGQLKRFSLRELQVASDNFSNKNILGRGGFGKVYKGRL 308 Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976 G +VAVK LK + ++ E++++ H ++++ +G C E+ L Sbjct 309 -----ADGTLVAVKRLKEERTQGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTER--LL 361 Query 977 VMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028 V Y+ GS+ L + + A G+AYLH IHRD+ A N Sbjct 362 VYPYMANGSVASCLRERPESQPPLDWPKRQRIALGSARGLAYLHDHCDPKIIHRDVKAAN 421 Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 +LLD + +GDFGLAK + + V + APE L K +DV+ +G Sbjct 422 ILLDEEFEAVVGDFGLAKLMDYKDTH--VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 479 Query 1089 VTLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 V L EL+T + + + L+ +G + +L L++ + D+ ++ Sbjct 480 VMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEALVDVDLQGNYKDEEVEQLI 539 Query 1146 HLMKNCWETEASFRPTFENLIPILK 1170 + C ++ RP ++ +L+ Sbjct 540 QVALLCTQSSPMERPKMSEVVRMLE 564 Score = 202 bits (515), Expect = 7e-54, Method: Composition-based stats. Identities = 71/365 (19%), Positives = 117/365 (32%), Gaps = 70/365 (19%) Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + S V + + LG+G VY+GRL Sbjct 273 QLKRFSLRELQVASDNFSNKNILGRGGFGKVYKGRLADG--------------------- 311 Query 633 RGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 V +K L L F ++S H +L + G C+ E ++V Y+ Sbjct 312 ----TLVAVKRLKEERTQGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMA 367 Query 692 HGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745 +G + LR R P+ W + +A A L+YL + ++H +V NILL Sbjct 368 NGSVASCLRERPESQPPLDWPKRQRIALGSARGLAYLHDHCDPKIIHRDVKAANILLDEE 427 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800 A + D G+ ++ V I +APE L G + S D +G+ Sbjct 428 FEAV-------VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 478 Query 801 GATLLEICFDGEAPLQSR--SPSEKEHFYQRQHRLPEPSCPQLAT--------------- 843 G LLE+ A +R + + + L E L Sbjct 479 GVMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEALVDVDLQGNYKDEEVEQL 538 Query 844 --LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901 + C P +RP + + L+ LA+ + + + Sbjct 539 IQVALLCTQSSPMERPKMSEV---VRMLEGDGLAERWEEWQKEEMFRQDFNYPTHHPAVS 595 Query 902 DLGEG 906 G Sbjct 596 GWIIG 600 >sp|Q9CAL8|PEK13_ARATH Proline-rich receptor-like protein kinase PERK13 OS=Arabidopsis thaliana OX=3702 GN=PERK13 PE=1 SV=1 Length=710 Score = 243 bits (620), Expect = 9e-67, Method: Composition-based stats. Identities = 81/305 (27%), Positives = 125/305 (41%), Gaps = 21/305 (7%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + + K LGEG FG V G++VAVK LK G Sbjct 334 MGSGQTHFTYEELTDITEGFSKHNILGEGGFGCVYKG-----KLNDGKLVAVKQLKVGSG 388 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHS 994 R +K E++I+ ++H H++ G C E+ L+ EYVP +L +L R Sbjct 389 QGDRE-FKAEVEIISRVHHRHLVSLVGYCIADSER--LLIYEYVPNQTLEHHLHGKGRPV 445 Query 995 IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 + A+ + A +G+AYLH IHRD+ + N+LLD++ ++ DFGLAK Sbjct 446 LEWARRVRIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDDEFEAQVADFGLAKLNDST 505 Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLE 1110 + R + APE + K SDV+SFGV L EL+T Q P Sbjct 506 QTHVSTR--VMGTFGYLAPEYAQSGKLTDRSDVFSFGVVLLELITGRKPVDQYQPLGEES 563 Query 1111 LIGIAQG----QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L+ A+ + +EL++R + + C RP ++ Sbjct 564 LVEWARPLLHKAIETGDFSELVDRRLEKHYVENEVFRMIETAAACVRHSGPKRPRMVQVV 623 Query 1167 PILKT 1171 L + Sbjct 624 RALDS 628 Score = 224 bits (572), Expect = 2e-60, Method: Composition-based stats. Identities = 64/307 (21%), Positives = 110/307 (36%), Gaps = 46/307 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + ++ + LG+G VY+G+L V +K L Sbjct 350 TEGFSKHNILGEGGFGCVYKGKLNDGK-------------------------LVAVKQLK 384 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RG 704 F ++S+V H HL + G C+ E +++ EYV + L+ L + R Sbjct 385 VGSGQGDREFKAEVEIISRVHHRHLVSLVGYCIADSERLLIYEYVPNQTLEHHLHGKGRP 444 Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 + A ++ +A A L+YL ++H ++ NILL A+ ++D G Sbjct 445 VLEWARRVRIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDDEFEAQ-------VADFG 497 Query 762 VGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 + S + V +LAPE G L+ D + FG LLE+ G P+ Sbjct 498 LAKLNDSTQTHVSTRVMGTFGYLAPEYAQSG--KLTDRSDVFSFGVVLLELI-TGRKPVD 554 Query 817 SRSPSEKEHFYQRQHRLPEPSCP--QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 P +E + L + + L + L + FR I ++ Sbjct 555 QYQPLGEESLVEWARPLLHKAIETGDFSELVDRRLEKHYVENEVFRMIETAAACVRHSGP 614 Query 875 ADVLTVN 881 V Sbjct 615 KRPRMVQ 621 >sp|Q8H199|CRK14_ARATH Cysteine-rich receptor-like protein kinase 14 OS=Arabidopsis thaliana OX=3702 GN=CRK14 PE=2 SV=2 Length=658 Score = 241 bits (616), Expect = 1e-66, Method: Composition-based stats. Identities = 75/292 (26%), Positives = 123/292 (42%), Gaps = 29/292 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG+V + G VA+K L Q +K E+ ++ L+H +++K Sbjct 343 IGRGGFGEVFMGVL------NGTEVAIKRLSK-ASRQGAREFKNEVVVVAKLHHRNLVKL 395 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 G C + EK LV E+VP SL +L + + + + I G+ YLH Sbjct 396 LGFCLEGEEK--ILVYEFVPNKSLDYFLFDPTKQGQLDWTKRYNIIRGITRGILYLHQDS 453 Query 1019 ---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 IHRDL A N+LLD D KI DFG+A+ ++ + PE +++ Sbjct 454 RLTIIHRDLKASNILLDADMNPKIADFGMARIFGIDQSGANTKKIA-GTRGYMPPEYVRQ 512 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSS--QSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +F SDV+SFGV + E++ ++ T L+ A EL++ Sbjct 513 GQFSTRSDVYSFGVLVLEIICGRNNRFIHQSDTTVENLVTYAWRLWRNDSPLELVD---- 568 Query 1134 LPRPDKCPCE----VYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 + C E H+ C + + RP+ + +L ++ Y P Sbjct 569 PTISENCETEEVTRCIHIALLCVQHNPTDRPSLSTINMML--INNSYVLPDP 618 Score = 238 bits (607), Expect = 2e-65, Method: Composition-based stats. Identities = 62/351 (18%), Positives = 119/351 (34%), Gaps = 66/351 (19%) Query 565 RGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 +G+ + Q F ++ + ++ + +G+G V+ G L Sbjct 311 QGSSTDITITHSLQFDFKAIEDATNKFSESNIIGRGGFGEVFMGVL-------------- 356 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 V +K L + A F +++++ H +L + G C+ G E Sbjct 357 ------------NGTEVAIKRLSKASRQGAREFKNEVVVVAKLHHRNLVKLLGFCLEGEE 404 Query 683 NIMVTEYVEHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCG 737 I+V E+V + LD +L ++G + + + + + + YL + ++H ++ Sbjct 405 KILVYEFVPNKSLDYFLFDPTKQGQLDWTKRYNIIRGITRGILYLHQDSRLTIIHRDLKA 464 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSL 791 NILL K++D G+ + ++ ++ PE + G Sbjct 465 SNILLD-------ADMNPKIADFGMARIFGIDQSGANTKKIAGTRGYMPPEYVRQG--QF 515 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP------------ 839 ST D + FG +LEI +S + E+ RL P Sbjct 516 STRSDVYSFGVLVLEIICGRNNRFIHQSDTTVENLVTYAWRLWRNDSPLELVDPTISENC 575 Query 840 ------QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884 + + C+ + PT RPS TI L Sbjct 576 ETEEVTRCIHIALLCVQHNPTDRPSLSTINMMLINNSYVLPDPQQPGFFFP 626 >sp|Q7X8C5|WAKLB_ARATH Wall-associated receptor kinase-like 2 OS=Arabidopsis thaliana OX=3702 GN=WAKL2 PE=2 SV=1 Length=748 Score = 244 bits (622), Expect = 1e-66, Method: Composition-based stats. Identities = 76/293 (26%), Positives = 119/293 (41%), Gaps = 18/293 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 K R LG+G G V G +VAVK KA + E+ +L + Sbjct 414 DNFNKNRVLGQGGQGTVYKGML-----VDGRIVAVKRSKA-VDEDRVEEFINEVVVLAQI 467 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEG 1010 H +I+K GCC + + LV E+VP G L L S + L A +I Sbjct 468 NHRNIVKLLGCCLET--EVPVLVYEFVPNGDLCKRLHDESDDYTMTWEVRLHIAIEIAGA 525 Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 ++YLH+ HRD+ N+LLD K+ DFG +++V + + G + Sbjct 526 LSYLHSAASFPIYHRDIKTTNILLDERNRAKVSDFGTSRSVTIDQTHLTTQVAG--TFGY 583 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 PE + KF SDV+SFGV L ELLT SS+ + L + R+ + Sbjct 584 VDPEYFQSSKFTEKSDVYSFGVVLVELLTGEKPSSRVRSEENRGLAAHFVEAVKENRVLD 643 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +++ + V +L + C + RP + L+ + + Sbjct 644 IVDDRIKDECNMDQVMSVANLARRCLNRKGKKRPNMREVSIELEMIRSSHYDS 696 Score = 224 bits (571), Expect = 5e-60, Method: Composition-based stats. Identities = 62/323 (19%), Positives = 111/323 (34%), Gaps = 63/323 (20%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + LGQG + VY+G L V +K Sbjct 412 ATDNFNKNRVLGQGGQGTVYKGMLVDGRI-------------------------VAVKRS 446 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D F +++Q++H ++ + G C+ ++V E+V +G L L E Sbjct 447 KAVDEDRVEEFINEVVVLAQINHRNIVKLLGCCLETEVPVLVYEFVPNGDLCKRLHDESD 506 Query 705 HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 M W ++ +A ++A ALSYL + + H ++ NILL A K+SD Sbjct 507 DYTMTWEVRLHIAIEIAGALSYLHSAASFPIYHRDIKTTNILLDERNRA-------KVSD 559 Query 760 PGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G + ++ PE ++ + D + FG L+E+ GE P Sbjct 560 FGTSRSVTIDQTHLTTQVAGTFGYVDPEYFQ--SSKFTEKSDVYSFGVVLVELL-TGEKP 616 Query 815 LQSRSPSEKEHFYQR--------------QHRLPEPSCPQ----LATLTSQCLTYEPTQR 856 E R+ + +A L +CL + +R Sbjct 617 SSRVRSEENRGLAAHFVEAVKENRVLDIVDDRIKDECNMDQVMSVANLARRCLNRKGKKR 676 Query 857 PSFRTILRDLTRLQPHNLADVLT 879 P+ R + +L ++ + + Sbjct 677 PNMREVSIELEMIRSSHYDSGIH 699 >sp|Q55EC7|GEFX_DICDI RasGEF domain-containing serine/threonine-protein kinase X OS=Dictyostelium discoideum OX=44689 GN=gefX PE=2 SV=1 Length=960 Score = 247 bits (631), Expect = 1e-66, Method: Composition-based stats. Identities = 72/294 (24%), Positives = 125/294 (43%), Gaps = 23/294 (8%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 P L+ +G+G FG V CY + VA+K ++ P++ Sbjct 9 PTQAIWDIPFESLEFNEKIGKGSFGSVFRGCYLGLD------VAIKKIEKADDPEYLKYI 62 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLF 1003 +E+ +L++L H I+ + G C L +V E+V G +R L + IG + + Sbjct 63 DREVSMLQSLRHPFIVNFSGICVHSS--GLYIVTEFVSGGDVRQLLKKTPPIGWDKRVSI 120 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 A + + M +LHA+ IHRDL ++N+LLD + +++ DFG A+ + + + Sbjct 121 AVDLAKAMVFLHAKKIIHRDLKSKNILLDEFQRIRLCDFGFARMSEQTKKSRHMTM--CG 178 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 W APE L + + DV+S+GV L EL+T G+ + Sbjct 179 TEGWVAPEILLGMSYDTSCDVFSYGVVLAELITGRKP------------GVDLWVRSPET 226 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 ++ + CP E+ + C E RP F+ ++ LK + Sbjct 227 CFDINPEELKQKSIPGCPSELISVCVECCLYEPLTRPKFDEILSQLKVCQNNLK 280 Score = 197 bits (500), Expect = 3e-50, Method: Composition-based stats. Identities = 64/311 (21%), Positives = 113/311 (36%), Gaps = 48/311 (15%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + + + + +G+G+ +V+ G Sbjct 5 DPGLPTQAIWDIPFESLEFNEKIGKGSFGSVFRGCYLG---------------------- 42 Query 633 RGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 L V +K + + S++ + H + G+CV +VTE+V Sbjct 43 ----LDVAIKKIEKADDPEYLKYIDREVSMLQSLRHPFIVNFSGICVHSSGLYIVTEFVS 98 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G + L++ + ++ +A LA A+ +L K ++H ++ +NILL Sbjct 99 GGDVRQLLKKT-PPIGWDKRVSIAVDLAKAMVFLHAKKIIHRDLKSKNILLDEFQR---- 153 Query 752 SPFIKLSDPGVGLGALSRE-----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 I+L D G + + W+APE L G S T+ D + +G L E Sbjct 154 ---IRLCDFGFARMSEQTKKSRHMTMCGTEGWVAPEILLGM--SYDTSCDVFSYGVVLAE 208 Query 807 ICFDGEA--PLQSRSPSEKEHFYQ---RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861 + + L RSP +Q +P +L ++ +C YEP RP F Sbjct 209 LITGRKPGVDLWVRSPETCFDINPEELKQKSIPGCPS-ELISVCVECCLYEPLTRPKFDE 267 Query 862 ILRDLTRLQPH 872 IL L Q + Sbjct 268 ILSQLKVCQNN 278 >sp|Q9SIT1|TMK3_ARATH Receptor-like kinase TMK3 OS=Arabidopsis thaliana OX=3702 GN=TMK3 PE=1 SV=1 Length=943 Score = 247 bits (631), Expect = 1e-66, Method: Composition-based stats. Identities = 75/285 (26%), Positives = 122/285 (43%), Gaps = 24/285 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIK 961 LG G FG V G +AVK +++ + + +K EI +L + H H++ Sbjct 591 LGRGGFGTVYKGEL-----HDGTKIAVKRMESSVVSDKGLTEFKSEITVLTKMRHRHLVA 645 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------RHSIGLAQLLLFAQQICEGMAYLH 1015 G C D E+ LV EY+P G+L +L R + + L A + G+ YLH Sbjct 646 LLGYCLDGNER--LLVYEYMPQGTLSQHLFHWKEEGRKPLDWTRRLAIALDVARGVEYLH 703 Query 1016 ---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Q +IHRDL N+LL +D K+ DFGL + P+G Y + + APE Sbjct 704 TLAHQSFIHRDLKPSNILLGDDMRAKVSDFGLVRLAPDGK--YSIETRVAGTFGYLAPEY 761 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQ---GQMTVLRLTELL 1128 + D++S GV L EL+T + ++ P + L+ + + Sbjct 762 AVTGRVTTKVDIFSLGVILMELITGRKALDETQPEDSVHLVTWFRRVAASKDENAFKNAI 821 Query 1129 ERGERLPRPDKCPCE-VYHLMKNCWETEASFRPTFENLIPILKTV 1172 + L E V+ L +C E RP +++ +L ++ Sbjct 822 DPNISLDDDTVASIEKVWELAGHCCAREPYQRPDMAHIVNVLSSL 866 Score = 221 bits (563), Expect = 4e-58, Method: Composition-based stats. Identities = 72/345 (21%), Positives = 123/345 (36%), Gaps = 71/345 (21%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ + LG+G VY+G L ++ +K ++ Sbjct 582 TNNFSEENILGRGGFGTVYKGELHDG-------------------------TKIAVKRME 616 Query 646 PS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--R 701 S F ++++++ H HL + G C+ G E ++V EY+ G L L + Sbjct 617 SSVVSDKGLTEFKSEITVLTKMRHRHLVALLGYCLDGNERLLVYEYMPQGTLSQHLFHWK 676 Query 702 ERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 E G P+ W ++ +A +A + YL +++ +H ++ NILL G K Sbjct 677 EEGRKPLDWTRRLAIALDVARGVEYLHTLAHQSFIHRDLKPSNILL-------GDDMRAK 729 Query 757 LSDPGVGL----GALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 +SD G+ G S E RV +LAPE G ++T +D + G L+E+ G Sbjct 730 VSDFGLVRLAPDGKYSIETRVAGTFGYLAPEYAVTG--RVTTKVDIFSLGVILMELI-TG 786 Query 812 EAPLQSRSPSEKEHFYQRQHRL----------------------PEPSCPQLATLTSQCL 849 L P + H R+ S ++ L C Sbjct 787 RKALDETQPEDSVHLVTWFRRVAASKDENAFKNAIDPNISLDDDTVASIEKVWELAGHCC 846 Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894 EP QRP I+ L+ L + + Sbjct 847 AREPYQRPDMAHIVNVLSSLTVQWKPTETDPDDVYGIDYDMPLPQ 891 >sp|Q8L4H4|NORK_MEDTR Nodulation receptor kinase OS=Medicago truncatula OX=3880 GN=NORK PE=1 SV=2 Length=925 Score = 247 bits (630), Expect = 1e-66, Method: Composition-based stats. Identities = 73/278 (26%), Positives = 126/278 (45%), Gaps = 18/278 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG V D G+ VAVK ++ Q + E+++L + HE+++ Sbjct 602 IGEGGFGSVYRGTLD-----DGQEVAVKV-RSSTSTQGTREFDNELNLLSAIQHENLVPL 655 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHA- 1016 G C + ++ LV ++ GSL D L R + L A G+AYLH Sbjct 656 LGYCNEYDQQ--ILVYPFMSNGSLLDRLYGEASKRKILDWPTRLSIALGAARGLAYLHTF 713 Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 + IHRD+ + N+LLD K+ DFG +K P+ + Y V + + PE K Sbjct 714 PGRSVIHRDVKSSNILLDQSMCAKVADFGFSKYAPQEGDSY-VSLEVRGTAGYLDPEYYK 772 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + SDV+SFGV L E+++ + P L+ A+ + ++ E+++ G + Sbjct 773 TQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRIEWSLVEWAKPYIRASKVDEIVDPGIK 832 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + V + C E +++RP +++ L+ Sbjct 833 GGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELED 870 Score = 219 bits (558), Expect = 2e-57, Method: Composition-based stats. Identities = 83/392 (21%), Positives = 135/392 (34%), Gaps = 100/392 (26%) Query 500 LRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETS 559 R R I LEG+G+++P + +L + DD F Sbjct 544 CRYRHKSI-------TLEGFGKTYPMATNIIFSLP-----SKDDFFI------------- 578 Query 560 NLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEG 619 +++++ + ++Q + +G+G +VY G L Sbjct 579 ------------KSVSVKPFTLEYIEQATEQYKTLIGEGGFGSVYRGTL----------- 615 Query 620 KMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR 679 D GQE V +KV + F +L+S + H +L + G C Sbjct 616 ------------DDGQE--VAVKVRSSTSTQGTREFDNELNLLSAIQHENLVPLLGYCNE 661 Query 680 GPENIMVTEYVEHGPLDVWLRRE---RGHVPMAWKMVVAQQLASALSYLEN---KNLVHG 733 + I+V ++ +G L L E R + ++ +A A L+YL ++++H Sbjct 662 YDQQILVYPFMSNGSLLDRLYGEASKRKILDWPTRLSIALGAARGLAYLHTFPGRSVIHR 721 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGG 787 +V NILL + S K++D G + E +L PE Sbjct 722 DVKSSNILLDQ-------SMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKT- 773 Query 788 ANSLSTAMDKWGFGATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCP--- 839 LS D + FG LLEI E P S E Y R ++ E P Sbjct 774 -QQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRIEWSLVEWAKPYIRASKVDEIVDPGIK 832 Query 840 ---------QLATLTSQCLTYEPTQRPSFRTI 862 ++ + QCL T RP I Sbjct 833 GGYHAEALWRVVEVALQCLEPYSTYRPCMVDI 864 >sp|B0LT89|STK24_RAT Serine/threonine-protein kinase 24 OS=Rattus norvegicus OX=10116 GN=Stk24 PE=2 SV=1 Length=431 Score = 235 bits (599), Expect = 1e-66, Method: Composition-based stats. Identities = 70/266 (26%), Positives = 121/266 (45%), Gaps = 24/266 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G FG+V + ++ T ++VA+K + + +QEI +L ++ K Sbjct 29 KIGKGSFGEV----FKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTK 84 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 Y G + L ++MEY+ GS D L + Q+ ++I +G+ YLH++ IH Sbjct 85 YYGSYLKDTK--LWIIMEYLGGGSALDLLEPGPLDEIQIATILREILKGLDYLHSEKKIH 142 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RD+ A NVLL VK+ DFG+A + + R FW APE +K+ + Sbjct 143 RDIKAANVLLSEHGEVKLADFGVAGQLTD---TQIKRNTFVGTPFWMAPEVIKQSAYDSK 199 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 +D+WS G+T EL + PP ++ +++ L+ + Sbjct 200 ADIWSLGITAIEL-----AKGEPP----------HSELHPMKVLFLIPKNNPPTLEGSYS 244 Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167 + ++ C E SFRPT + L+ Sbjct 245 RPLKEFVEACLNKEPSFRPTAKELLK 270 Score = 213 bits (542), Expect = 5e-59, Method: Composition-based stats. Identities = 63/310 (20%), Positives = 119/310 (38%), Gaps = 44/310 (14%) Query 570 SPRTLNLSQLSFHRVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 SP L + + D +E T+L +G+G+ V++G Sbjct 4 SPVQSGLPGMQTLKADPEELFTKLEKIGKGSFGEVFKGI--------------------- 42 Query 629 PGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 D + V +K++D D + +++SQ ++ +G ++ + ++ Sbjct 43 ---DNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIM 99 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 EY+ G L E G + + +++ L YL ++ +H ++ N+LL+ G Sbjct 100 EYLGGGSALDLL--EPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE 157 Query 748 AEGTSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +KL+D GV + R V W+APE + A + D W G T Sbjct 158 -------VKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSA--YDSKADIWSLGIT 208 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861 +E+ GE P P + + + L L CL EP+ RP+ + Sbjct 209 AIELA-KGEPPHSELHPMKVLFLIPKNNPPTLEGSYSRPLKEFVEACLNKEPSFRPTAKE 267 Query 862 ILRDLTRLQP 871 +L+ ++ Sbjct 268 LLKHKFIIRN 277 >sp|Q8L7G3|CRK7_ARATH Cysteine-rich receptor-like protein kinase 7 OS=Arabidopsis thaliana OX=3702 GN=CRK7 PE=2 SV=1 Length=659 Score = 241 bits (615), Expect = 1e-66, Method: Composition-based stats. Identities = 69/280 (25%), Positives = 113/280 (40%), Gaps = 17/280 (6%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G G FG V + G VAVK L Q + +K E+ ++ L H+++ Sbjct 339 NNKIGRGGFGDVYKGTF-----SNGTEVAVKRLSK-TSEQGDTEFKNEVVVVANLRHKNL 392 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015 ++ G ++ E+ LV EYV SL ++L + + Q I G+ YLH Sbjct 393 VRILGFSIEREER--ILVYEYVENKSLDNFLFDPAKKGQLYWTQRYHIIGGIARGILYLH 450 Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 IHRDL A N+LLD D KI DFG+A+ + +PE Sbjct 451 QDSRLTIIHRDLKASNILLDADMNPKIADFGMARIFGMDQTQQNTSR-IVGTYGYMSPEY 509 Query 1073 LKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 +F SDV+SFGV + E+++ ++S +L+ A +L++ Sbjct 510 AMRGQFSMKSDVYSFGVLVLEIISGRKNNSFIETDDAQDLVTHAWRLWRNGTALDLVDPF 569 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 H+ C + + RP + +L + Sbjct 570 IADSCRKSEVVRCTHIGLLCVQEDPVKRPAMSTISVMLTS 609 Score = 231 bits (588), Expect = 5e-63, Method: Composition-based stats. Identities = 61/354 (17%), Positives = 116/354 (33%), Gaps = 66/354 (19%) Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTR 600 F C + + + T+ QL + + + ++ + +G+G Sbjct 288 LIFIAGYCFFAKRAKKTYGTTPALDEDDKTTIESLQLDYRAIQAATNDFSENNKIGRGGF 347 Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660 +VY+G V +K L + F Sbjct 348 GDVYKGT-------------------------FSNGTEVAVKRLSKTSEQGDTEFKNEVV 382 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR--ERGHVPMAWKMVVAQQL 718 +++ + H +L + G + E I+V EYVE+ LD +L ++G + + + + Sbjct 383 VVANLRHKNLVRILGFSIEREERILVYEYVENKSLDNFLFDPAKKGQLYWTQRYHIIGGI 442 Query 719 ASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSR 769 A + YL + ++H ++ NILL K++D G+ + Sbjct 443 ARGILYLHQDSRLTIIHRDLKASNILLD-------ADMNPKIADFGMARIFGMDQTQQNT 495 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 V +++PE G S D + FG +LEI G + + Sbjct 496 SRIVGTYGYMSPEYAMRG--QFSMKSDVYSFGVLVLEIIS-GRKNNSFIETDDAQDLVTH 552 Query 830 QHRLPEP------SCPQLAT------------LTSQCLTYEPTQRPSFRTILRD 865 RL P +A + C+ +P +RP+ TI Sbjct 553 AWRLWRNGTALDLVDPFIADSCRKSEVVRCTHIGLLCVQEDPVKRPAMSTISVM 606 >sp|P48025|KSYK_MOUSE Tyrosine-protein kinase SYK OS=Mus musculus OX=10090 GN=Syk PE=1 SV=2 Length=629 Score = 240 bits (613), Expect = 1e-66, Method: Composition-based stats. Identities = 102/325 (31%), Positives = 148/325 (46%), Gaps = 23/325 (7%) Query 851 YEPTQRPS--FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 YEPT P R + R+ + + + + + +LG G+F Sbjct 317 YEPTGGPWGPDRGLQREALPMDTEVYESPYADPEEIRPKEVYLDRSLLTLEDNELGSGNF 376 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 G V Y V + LK + P + E ++++ L + +I++ G CE Sbjct 377 GTVKKGYYQMKKVVKTVAVKI--LKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICE 434 Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 +S LVME LG L YL ++ I ++ Q+ GM YL +++HRDLAA Sbjct 435 ---AESWMLVMEMAELGPLNKYLQQNRHIKDKNIIELVHQVSMGMKYLEESNFVHRDLAA 491 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RNVLL KI DFGL+KA+ YY+ + G PV WYAPEC+ YKF SDVWS Sbjct 492 RNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWS 551 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 FGV ++E ++ M +T +LE+GER+ P CP E+Y Sbjct 552 FGVLMWEAFSYGQK--------------PYRGMKGSEVTAMLEKGERMGCPAGCPREMYD 597 Query 1147 LMKNCWETEASFRPTFENLIPILKT 1171 LM CW + RP F + L+ Sbjct 598 LMNLCWTYDVENRPGFTAVELRLRN 622 Score = 207 bits (528), Expect = 2e-55, Method: Composition-based stats. Identities = 65/290 (22%), Positives = 115/290 (40%), Gaps = 40/290 (14%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + + LG G V +G +++ K+ + P LK Sbjct 367 EDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDP----------ALK-------- 408 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 A++M Q+ + ++ + G+C ++V E E GPL+ +L++ R H+ Sbjct 409 --DELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNR-HIKDKN 464 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + + Q++ + YLE N VH ++ RN+LL T + K+SD G+ + E Sbjct 465 IIELVHQVSMGMKYLEESNFVHRDLAARNVLL-------VTQHYAKISDFGLSKALRADE 517 Query 771 ERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + + W APEC+ S+ D W FG + E G+ P + SE Sbjct 518 NYYKAQTHGKWPVKWYAPECI--NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEV 575 Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 ++ R+ P ++ L + C TY+ RP F + L Sbjct 576 TAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFTAVELRLRNYYY 625 Score = 37.4 bits (85), Expect = 0.86, Method: Composition-based stats. Identities = 21/107 (20%), Positives = 35/107 (33%), Gaps = 15/107 (14%) Query 453 GPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQ 509 G + + L DGLYL+ S ++ L+VA +A + IE+ Sbjct 17 GNITREEAEDYLVQGGMTDGLYLLRQSRNYLGGFALSVAHNRKA---------HHYTIER 67 Query 510 QDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPG 556 + GR+ S +L L++ PG Sbjct 68 ELNGTYAISGGRAHASPADL---CHYHSQEPDGLICLLKKPFNRPPG 111 >sp|Q9M2S4|LRKS4_ARATH L-type lectin-domain containing receptor kinase S.4 OS=Arabidopsis thaliana OX=3702 GN=LECRKS4 PE=2 SV=1 Length=684 Score = 242 bits (617), Expect = 1e-66, Method: Composition-based stats. Identities = 78/291 (27%), Positives = 126/291 (43%), Gaps = 22/291 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FGKV Y G+ E VAVK + + Q + E+ + L H ++++ Sbjct 352 LGSGGFGKV----YKGKLPGSDEFVAVKRISHE-SRQGVREFMSEVSSIGHLRHRNLVQL 406 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA-- 1016 G C + + L LV +++P GSL YL + + Q + + G+ YLH Sbjct 407 LGWCRRRDD--LLLVYDFMPNGSLDMYLFDENPEVILTWKQRFKIIKGVASGLLYLHEGW 464 Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 Q IHRD+ A NVLLD++ ++GDFGLAK G + R + APE K Sbjct 465 EQTVIHRDIKAANVLLDSEMNGRVGDFGLAKLYEHGSDPGATR--VVGTFGYLAPELTKS 522 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 K ++DV++FG L E+ + S + L ++ + + ++++R Sbjct 523 GKLTTSTDVYAFGAVLLEVACGRRPIETSALPEELVMVDWVWSRWQSGDIRDVVDRRLNG 582 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 ++ V L C RPT ++ L+ Q +P V Sbjct 583 EFDEEEVVMVIKLGLLCSNNSPEVRPTMRQVVMYLEK-----QFPSPEVVP 628 Score = 219 bits (557), Expect = 1e-58, Method: Composition-based stats. Identities = 61/308 (20%), Positives = 104/308 (34%), Gaps = 60/308 (19%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 LG G VY+G+L G + V +K + Sbjct 342 ATNGFGDKELLGSGGFGKVYKGKL------------------------PGSDEFVAVKRI 377 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 F S + + H +L + G C R + ++V +++ +G LD++L E Sbjct 378 SHESRQGVREFMSEVSSIGHLRHRNLVQLLGWCRRRDDLLLVYDFMPNGSLDMYLFDENP 437 Query 705 HVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 V + W + + + +AS L YL + ++H ++ N+LL + ++ D Sbjct 438 EVILTWKQRFKIIKGVASGLLYLHEGWEQTVIHRDIKAANVLLD-------SEMNGRVGD 490 Query 760 PGVGLGALSREE-----RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ + V +LAPE G L+T+ D + FGA LLE+ Sbjct 491 FGLAKLYEHGSDPGATRVVGTFGYLAPELTKSG--KLTTSTDVYAFGAVLLEVACGRRPI 548 Query 815 LQSRSPSEKEHFYQR-----------------QHRLPEPSCPQLATLTSQCLTYEPTQRP 857 S P E E + L C P RP Sbjct 549 ETSALPEELVMVDWVWSRWQSGDIRDVVDRRLNGEFDEEEVVMVIKLGLLCSNNSPEVRP 608 Query 858 SFRTILRD 865 + R ++ Sbjct 609 TMRQVVMY 616 >sp|O64770|Y1649_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61490 OS=Arabidopsis thaliana OX=3702 GN=At1g61490 PE=3 SV=1 Length=804 Score = 244 bits (623), Expect = 1e-66, Method: Composition-based stats. Identities = 74/307 (24%), Positives = 123/307 (40%), Gaps = 17/307 (6%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 + LG+G FG V G+ +AVK L + G Q + Sbjct 477 FFEMNTIQTATNNFSLSNKLGQGGFGSVYKGKLQ-----DGKEIAVKQLSSSSG-QGKEE 530 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ 999 + EI ++ L H ++++ GCC + EK L+ E++ SL ++ + + + Sbjct 531 FMNEIVLISKLQHRNLVRVLGCCIEGEEK--LLIYEFMLNKSLDTFVFDARKKLEVDWPK 588 Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 Q I G+ YLH IHRDL N+LLD KI DFGLA+ + EG + Sbjct 589 RFDIVQGIARGLLYLHRDSRLKVIHRDLKVSNILLDEKMNPKISDFGLAR-MYEGTQCQD 647 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH-CDSSQSPPTKFLELIGIA 1115 + + +PE F SD++SFGV L E++ S S + L+ A Sbjct 648 KTRRVVGTLGYMSPEYAWTGVFSEKSDIYSFGVLLLEIIIGEKISRFSYGEEGKTLLAYA 707 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 + +LL++ + C + + + RP L+ +L T + Sbjct 708 WESWGETKGIDLLDQDLADSCRPLEVGRCVQIGLLCVQHQPADRPNTLELLAMLTTTSDL 767 Query 1176 YQGQAPS 1182 + P+ Sbjct 768 PSPKQPT 774 Score = 229 bits (585), Expect = 1e-61, Method: Composition-based stats. Identities = 53/247 (21%), Positives = 94/247 (38%), Gaps = 45/247 (18%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L +++ + + + LGQG +VY+G+L+ Sbjct 475 LEFFEMNTIQTATNNFSLSNKLGQGGFGSVYKGKLQDGK--------------------- 513 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + +K L S F L+S++ H +L V G C+ G E +++ E++ + Sbjct 514 ----EIAVKQLSSSSGQGKEEFMNEIVLISKLQHRNLVRVLGCCIEGEEKLLIYEFMLNK 569 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748 LD ++ R + + W + + Q +A L YL ++H ++ NILL Sbjct 570 SLDTFVFDARKKLEVDWPKRFDIVQGIARGLLYLHRDSRLKVIHRDLKVSNILLDEK--- 626 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 K+SD G+ V + +++PE G S D + FG Sbjct 627 ----MNPKISDFGLARMYEGTQCQDKTRRVVGTLGYMSPEYAWTGV--FSEKSDIYSFGV 680 Query 803 TLLEICF 809 LLEI Sbjct 681 LLLEIII 687 >sp|Q9SGY7|PEK11_ARATH Putative proline-rich receptor-like protein kinase PERK11 OS=Arabidopsis thaliana OX=3702 GN=PERK11 PE=2 SV=2 Length=718 Score = 243 bits (619), Expect = 1e-66, Method: Composition-based stats. Identities = 73/299 (24%), Positives = 127/299 (42%), Gaps = 21/299 (7%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 + K +GEG FG V G+ VA+K LK+ +R Sbjct 357 HFTYEELSQITEGFCKSFVVGEGGFGCVYKGIL-----FEGKPVAIKQLKSVSAEGYRE- 410 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQL 1000 +K E++I+ ++H H++ G C + + L+ E+VP +L +L ++ ++ Sbjct 411 FKAEVEIISRVHHRHLVSLVGYCISEQHR--FLIYEFVPNNTLDYHLHGKNLPVLEWSRR 468 Query 1001 LLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + A +G+AYLH IHRD+ + N+LLD++ ++ DFGLA+ + Sbjct 469 VRIAIGAAKGLAYLHEDCHPKIIHRDIKSSNILLDDEFEAQVADFGLARLNDTAQSHIST 528 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQ 1116 R + APE K SDV+SFGV L EL+T S P L+ A+ Sbjct 529 R--VMGTFGYLAPEYASSGKLTDRSDVFSFGVVLLELITGRKPVDTSQPLGEESLVEWAR 586 Query 1117 GQMTVL----RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 ++ ++E+++ + ++ +C A RP ++ L T Sbjct 587 PRLIEAIEKGDISEVVDPRLENDYVESEVYKMIETAASCVRHSALKRPRMVQVVRALDT 645 Score = 215 bits (548), Expect = 2e-57, Method: Composition-based stats. Identities = 59/306 (19%), Positives = 112/306 (37%), Gaps = 51/306 (17%) Query 546 SLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSH-------LGQG 598 + +T++L + R +P + + H +E++Q++ +G+G Sbjct 321 NGNSSAQNSSPDTNSLGNPKHGRGTPDSAVIGTSKIH-FTYEELSQITEGFCKSFVVGEG 379 Query 599 TRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYET 658 VY+G L V +K L + F Sbjct 380 GFGCVYKGILFEGKP-------------------------VAIKQLKSVSAEGYREFKAE 414 Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQ 717 ++S+V H HL + G C+ ++ E+V + LD L + + + ++ +A Sbjct 415 VEIISRVHHRHLVSLVGYCISEQHRFLIYEFVPNNTLDYHLHGKNLPVLEWSRRVRIAIG 474 Query 718 LASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-- 772 A L+YL ++H ++ NILL A+ ++D G+ + + Sbjct 475 AAKGLAYLHEDCHPKIIHRDIKSSNILLDDEFEAQ-------VADFGLARLNDTAQSHIS 527 Query 773 ---VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 + +LAPE G L+ D + FG LLE+ + S+ E+ Sbjct 528 TRVMGTFGYLAPEYASSG--KLTDRSDVFSFGVVLLELITGRKPVDTSQPLGEESLVEWA 585 Query 830 QHRLPE 835 + RL E Sbjct 586 RPRLIE 591 >sp|Q3E9X6|CRK21_ARATH Cysteine-rich receptor-like protein kinase 21 OS=Arabidopsis thaliana OX=3702 GN=CRK21 PE=2 SV=1 Length=690 Score = 242 bits (617), Expect = 2e-66, Method: Composition-based stats. Identities = 75/298 (25%), Positives = 109/298 (37%), Gaps = 18/298 (6%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 K LG G FG V + G VA K L Q +K E+ ++ L Sbjct 362 NFHKSNKLGHGGFGAVYKGMF-----PNGTEVAAKRLSK-PSDQGEPEFKNEVLLVARLQ 415 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGM 1011 H++++ G + EK LV E+VP SL +L R + + + I G+ Sbjct 416 HKNLVGLLGFSVEGEEK--ILVYEFVPNKSLDHFLFDPIKRVQLDWPRRHNIIEGITRGI 473 Query 1012 AYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 YLH IHRDL A N+LLD + KI DFGLA+ + Sbjct 474 LYLHQDSRLTIIHRDLKASNILLDAEMNPKIADFGLARNFRVNQTEANT-GRVVGTFGYM 532 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLTE 1126 PE + +F SDV+SFGV + E++ S L+ L E Sbjct 533 PPEYVANGQFSTKSDVYSFGVLILEIIGGKKNSSFHQIDGSVSNLVTHVWRLRNNGSLLE 592 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 L++ H+ C + RP+ + +L V P F Sbjct 593 LVDPAIGENYDKDEVIRCIHIGLLCVQENPDDRPSMSTIFRMLTNVSITLPVPQPPGF 650 Score = 218 bits (555), Expect = 2e-58, Method: Composition-based stats. Identities = 68/385 (18%), Positives = 117/385 (30%), Gaps = 64/385 (17%) Query 536 CLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHL 595 + + FS+ R +P T++ + + + + L Sbjct 311 QSFASENGYFSVSRR-PRRPYGTASPDDATDDLTASSGSLRFDFRAIKAATSNFHKSNKL 369 Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655 G G VY+G V K L F Sbjct 370 GHGGFGAVYKGM-------------------------FPNGTEVAAKRLSKPSDQGEPEF 404 Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMV 713 L++++ H +L + G V G E I+V E+V + LD +L V + W + Sbjct 405 KNEVLLVARLQHKNLVGLLGFSVEGEEKILVYEFVPNKSLDHFLFDPIKRVQLDWPRRHN 464 Query 714 VAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + + + + YL + ++H ++ NILL K++D G+ + Sbjct 465 IIEGITRGILYLHQDSRLTIIHRDLKASNILLD-------AEMNPKIADFGLARNFRVNQ 517 Query 771 E------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 V ++ PE + G ST D + FG +LEI + + Sbjct 518 TEANTGRVVGTFGYMPPEYVANG--QFSTKSDVYSFGVLILEIIGGKKNSSFHQIDGSVS 575 Query 825 HFYQRQHRLPEPSC------PQLAT------------LTSQCLTYEPTQRPSFRTILRDL 866 + RL P + + C+ P RPS TI R L Sbjct 576 NLVTHVWRLRNNGSLLELVDPAIGENYDKDEVIRCIHIGLLCVQENPDDRPSMSTIFRML 635 Query 867 TRLQPHNLADVLTVNPDSPASDPTV 891 T + S+P Sbjct 636 TNVSITLPVPQPPGFFFRERSEPNP 660 >sp|Q9LW83|CE101_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase CES101 OS=Arabidopsis thaliana OX=3702 GN=CES101 PE=2 SV=2 Length=850 Score = 245 bits (625), Expect = 2e-66, Method: Composition-based stats. Identities = 77/285 (27%), Positives = 119/285 (42%), Gaps = 19/285 (7%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 Y LGEG FG V GE VA+K L G Q +K E ++ L Sbjct 525 DYFSDANKLGEGGFGPVYKGRL-----IDGEEVAIKRLSLASG-QGLVEFKNEAMLIAKL 578 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL----RDYLPRHSIGLAQLLLFAQQICEG 1010 H +++K GCC ++ EK L+ EY+P SL D L + + + I +G Sbjct 579 QHTNLVKLLGCCVEKDEK--MLIYEYMPNKSLDYFLFDPLRKIVLDWKLRFRIMEGIIQG 636 Query 1011 MAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH IHRD+ A N+LLD D KI DFG+A+ + + Sbjct 637 LLYLHKYSRLKVIHRDIKAGNILLDEDMNPKISDFGMARIFGAQESKANTKRVA-GTFGY 695 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHC--DSSQSPPTKFLELIGIAQGQMTVLRLT 1125 +PE +E F SDV+SFGV + E++ +S L LI R+ Sbjct 696 MSPEYFREGLFSAKSDVFSFGVLMLEIICGRKNNSFHHDSEGPLNLIVHVWNLFKENRVR 755 Query 1126 ELLERGERLPRPDK-CPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 E+++ + + C + A RP+ +++ ++ Sbjct 756 EVIDPSLGDSAVENPQVLRCVQVALLCVQQNADDRPSMLDVVSMI 800 Score = 228 bits (580), Expect = 1e-60, Method: Composition-based stats. Identities = 58/325 (18%), Positives = 108/325 (33%), Gaps = 64/325 (20%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + + + LG+G VY+GRL Sbjct 511 ELQIFSFESVAFATDYFSDANKLGEGGFGPVYKGRLIDGE-------------------- 550 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 V +K L + + F A L++++ HT+L + G CV E +++ EY+ + Sbjct 551 -----EVAIKRLSLASGQGLVEFKNEAMLIAKLQHTNLVKLLGCCVEKDEKMLIYEYMPN 605 Query 693 GPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGL 747 LD +L + + W + + + + L YL ++H ++ NILL Sbjct 606 KSLDYFLFDPLRKIVLDWKLRFRIMEGIIQGLLYLHKYSRLKVIHRDIKAGNILLDE--- 662 Query 748 AEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 K+SD G+ + + +++PE G S D + FG Sbjct 663 ----DMNPKISDFGMARIFGAQESKANTKRVAGTFGYMSPEYFREGL--FSAKSDVFSFG 716 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFY------QRQHRLPEPSCPQLAT------------ 843 +LEI + + +++R+ E P L Sbjct 717 VLMLEIICGRKNNSFHHDSEGPLNLIVHVWNLFKENRVREVIDPSLGDSAVENPQVLRCV 776 Query 844 -LTSQCLTYEPTQRPSFRTILRDLT 867 + C+ RPS ++ + Sbjct 777 QVALLCVQQNADDRPSMLDVVSMIY 801 >sp|Q8S9L6|CRK29_ARATH Cysteine-rich receptor-like protein kinase 29 OS=Arabidopsis thaliana OX=3702 GN=CRK29 PE=2 SV=1 Length=679 Score = 241 bits (616), Expect = 2e-66, Method: Composition-based stats. Identities = 75/286 (26%), Positives = 118/286 (41%), Gaps = 28/286 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +LG G FG V + G+ +AVK L + G Q + +K EI +L L H +++ Sbjct 361 NELGRGGFGSVYKGVFPQ-----GQEIAVKRLSGNSG-QGDNEFKNEILLLAKLQHRNLV 414 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016 + G C E+ LV E++ SL ++ R + I G+ YLH Sbjct 415 RLIGFCIQGEER--LLVYEFIKNASLDQFIFDTEKRQLLDWVVRYKMIGGIARGLLYLHE 472 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE-YYRVREDGDSPVFWYAPEC 1072 IHRDL A N+LLD + KI DFGLAK G +R + APE Sbjct 473 DSRFRIIHRDLKASNILLDQEMNPKIADFGLAKLFDSGQTMTHRFTSRIAGTYGYMAPEY 532 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS---SQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 +F +DV+SFGV + E++T + + +L+ + +++ Sbjct 533 AMHGQFSVKTDVFSFGVLVIEIITGKRNNNGGSNGDEDAEDLLSWVWRSWREDTILSVID 592 Query 1130 R----GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 G R H+ C + A+ RPT + +L + Sbjct 593 PSLTAGSRNEI-----LRCIHIGLLCVQESAATRPTMATVSLMLNS 633 Score = 227 bits (578), Expect = 2e-61, Method: Composition-based stats. Identities = 46/260 (18%), Positives = 90/260 (35%), Gaps = 47/260 (18%) Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 + + + LG+G +VY+G Q Sbjct 347 FETLKTATDNFSSENELGRGGFGSVYKGV-------------------------FPQGQE 381 Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 + +K L + F L++++ H +L + G C++G E ++V E++++ LD + Sbjct 382 IAVKRLSGNSGQGDNEFKNEILLLAKLQHRNLVRLIGFCIQGEERLLVYEFIKNASLDQF 441 Query 699 LRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSP 753 + + W + + +A L YL ++H ++ NILL + Sbjct 442 IFDTEKRQLLDWVVRYKMIGGIARGLLYLHEDSRFRIIHRDLKASNILLDQE-------M 494 Query 754 FIKLSDPGVGLGALSREERV--------ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 K++D G+ S + ++APE G S D + FG ++ Sbjct 495 NPKIADFGLAKLFDSGQTMTHRFTSRIAGTYGYMAPEYAMHG--QFSVKTDVFSFGVLVI 552 Query 806 EICFDGEAPLQSRSPSEKEH 825 EI + E Sbjct 553 EIITGKRNNNGGSNGDEDAE 572 >sp|O64768|RAF24_ARATH RAF-like serine/threonine-protein kinase 24 OS=Arabidopsis thaliana OX=3702 GN=RAF24 PE=1 SV=1 Length=1257 Score = 249 bits (636), Expect = 2e-66, Method: Composition-based stats. Identities = 80/298 (27%), Positives = 125/298 (42%), Gaps = 38/298 (13%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-----GPQHR--SGWKQEIDILRTL 954 +LG G FG V + T+ VA+K +K C Q R S + E +IL L Sbjct 979 ELGSGTFGTVYHGKWRGTD------VAIKRIKRSCFIGRSSEQERLTSEFWHEAEILSKL 1032 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAY 1013 +H +++ + G +D +L V EY+ GSLR L + + L+ A GM Y Sbjct 1033 HHPNVMAFYGVVKDGPGGTLATVTEYMVNGSLRHVLLSNRHLDRRKRLIIAMDAAFGMEY 1092 Query 1014 LHAQHYIHRDLAARNVLLD----NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 LH++ +H DL N+L++ + K+GDFGL+K V + W A Sbjct 1093 LHSKSIVHFDLKCDNLLVNLKDPARPICKVGDFGLSKI----KRNTLVTGGVRGTLPWMA 1148 Query 1070 PECLKE--YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 PE L K DV+SFG+ L+E+LT + + + + + Sbjct 1149 PELLSGSSSKVSEKVDVFSFGIVLWEILTGEEPYANMHYGAI--------------IGGI 1194 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 + R P+ C E LM+ CW + RP F + L+T+ P + Sbjct 1195 VNNTLRPTVPNYCDPEWRMLMEQCWAPDPFVRPAFPEIARRLRTMSSSAVHTKPHAVN 1252 Score = 237 bits (605), Expect = 1e-62, Method: Composition-based stats. Identities = 74/323 (23%), Positives = 124/323 (38%), Gaps = 47/323 (15%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 S + ++ +L LG GT VY G+ R V Sbjct 965 SLQVIKNDDLEELKELGSGTFGTVYHGKWRGTD--------------------------V 998 Query 640 VLKVLDPS--------HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEY 689 +K + S + F+ A ++S++ H ++ +GV GP + VTEY Sbjct 999 AIKRIKRSCFIGRSSEQERLTSEFWHEAEILSKLHHPNVMAFYGVVKDGPGGTLATVTEY 1058 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 + +G L L R H+ ++++A A + YL +K++VH ++ N+L+ L + Sbjct 1059 MVNGSLRHVLLSNR-HLDRRKRLIIAMDAAFGMEYLHSKSIVHFDLKCDNLLV---NLKD 1114 Query 750 GTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 P K+ D G+ L +PW+APE L G ++ +S +D + FG L E Sbjct 1115 PARPICKVGDFGLSKIKRNTLVTGGVRGTLPWMAPELLSGSSSKVSEKVDVFSFGIVLWE 1174 Query 807 ICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 I GE P + + +P P+ L QC +P RP+F I Sbjct 1175 IL-TGEEPYANMHYGAIIGGIVNNTLRPTVPNYCDPEWRMLMEQCWAPDPFVRPAFPEIA 1233 Query 864 RDLTRLQPHNLADVLTVNPDSPA 886 R L + + Sbjct 1234 RRLRTMSSSAVHTKPHAVNHQIH 1256 >sp|O49339|PTI12_ARATH PTI1-like tyrosine-protein kinase 2 OS=Arabidopsis thaliana OX=3702 GN=PTI12 PE=1 SV=1 Length=366 Score = 232 bits (591), Expect = 2e-66, Method: Composition-based stats. Identities = 69/286 (24%), Positives = 123/286 (43%), Gaps = 22/286 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG +G+V G+ VA+K L + + + ++ ++ L HE++I+ Sbjct 77 IGEGSYGRVYYATL-----NDGKAVALKKLDVAPEAETNTEFLNQVSMVSRLKHENLIQL 131 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------IGLAQLLLFAQQICEGMA 1012 G C D+ + L E+ +GSL D L + + A + G+ Sbjct 132 VGYCVDENLR--VLAYEFATMGSLHDILHGRKGVQGAQPGPTLDWLTRVKIAVEAARGLE 189 Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH + IHRD+ + NVLL D K+ DF L+ P+ ++A Sbjct 190 YLHEKVQPPVIHRDIRSSNVLLFEDYQAKVADFNLSNQAPDNAARLH-STRVLGTFGYHA 248 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE + SDV+SFGV L ELLT + P L+ A +++ ++ + + Sbjct 249 PEYAMTGQLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRLSEDKVKQCV 308 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + + P K ++ + C + E+ FRP ++ L+ + + Sbjct 309 DPKLKGEYPPKSVAKLAAVAALCVQYESEFRPNMSIVVKALQPLLK 354 Score = 196 bits (497), Expect = 1e-53, Method: Composition-based stats. Identities = 58/310 (19%), Positives = 101/310 (33%), Gaps = 54/310 (17%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVE 611 Q + ++ A+ + + LS V S +G+G+ VY L Sbjct 34 QKNQKPQAVVKPEAQKEALPIEVPPLSVDEVKEKTDNFGSKSLIGEGSYGRVYYATLNDG 93 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHL 670 V LK LD + + F S++S++ H +L Sbjct 94 K-------------------------AVALKKLDVAPEAETNTEFLNQVSMVSRLKHENL 128 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG--------HVPMAWKMVVAQQLASAL 722 + G CV ++ E+ G L L +G + ++ +A + A L Sbjct 129 IQLVGYCVDENLRVLAYEFATMGSLHDILHGRKGVQGAQPGPTLDWLTRVKIAVEAARGL 188 Query 723 SYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG------LGALSREERV 773 YL K ++H ++ N+LL A K++D + L + Sbjct 189 EYLHEKVQPPVIHRDIRSSNVLLFEDYQA-------KVADFNLSNQAPDNAARLHSTRVL 241 Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833 + APE G L+ D + FG LLE+ + + ++ RL Sbjct 242 GTFGYHAPEYAMTG--QLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRL 299 Query 834 PEPSCPQLAT 843 E Q Sbjct 300 SEDKVKQCVD 309 >sp|Q9ZP16|CRK11_ARATH Cysteine-rich receptor-like protein kinase 11 OS=Arabidopsis thaliana OX=3702 GN=CRK11 PE=2 SV=2 Length=667 Score = 241 bits (614), Expect = 2e-66, Method: Composition-based stats. Identities = 70/282 (25%), Positives = 109/282 (39%), Gaps = 20/282 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LGEG FG V G VAVK L G Q ++ E ++ L H +++ Sbjct 354 NKLGEGGFGAVYKG-----KLSNGTDVAVKRLSKKSG-QGTREFRNEAVLVTKLQHRNLV 407 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH- 1015 + G C ++ E+ L+ E+V SL +L + + + I G+ YLH Sbjct 408 RLLGFCLEREEQ--ILIYEFVHNKSLDYFLFDPEKQSQLDWTRRYKIIGGIARGILYLHQ 465 Query 1016 --AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRDL A N+LLD D KI DFGLA + + +PE Sbjct 466 DSRLKIIHRDLKASNILLDADMNPKIADFGLATIFGV-EQTQGNTNRIAGTYAYMSPEYA 524 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL----ELIGIAQGQMTVLRLTELLE 1129 ++ SD++SFGV + E+++ +S L+ A EL++ Sbjct 525 MHGQYSMKSDIYSFGVLVLEIISGKKNSGVYQMDETSTAGNLVTYASRLWRNKSPLELVD 584 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 H+ C + RP +I +L + Sbjct 585 PTFGRNYQSNEVTRCIHIALLCVQENPEDRPMLSTIILMLTS 626 Score = 230 bits (586), Expect = 1e-62, Method: Composition-based stats. Identities = 72/435 (17%), Positives = 126/435 (29%), Gaps = 74/435 (17%) Query 466 PEDGLYLIHWSTS---HPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRS 522 + G ++ S Y + A + P QD + G S Sbjct 228 QKRGGVVMRPSCFLRWDLYTYSNAFDNLTVASPPPEPPVTVPQPAGDQDNPTNNDSKGIS 287 Query 523 FPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFH 582 V + +L F L R + + S + Sbjct 288 AGVVVAITVPTVIAILILLVLGFVLFRRRKSYQRTKTE----SESDISTTDSLVYDFKTI 343 Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 + + + LG+G VY+G+L V +K Sbjct 344 EAATNKFSTSNKLGEGGFGAVYKGKLSNG-------------------------TDVAVK 378 Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 L F A L++++ H +L + G C+ E I++ E+V + LD +L Sbjct 379 RLSKKSGQGTREFRNEAVLVTKLQHRNLVRLLGFCLEREEQILIYEFVHNKSLDYFLFDP 438 Query 703 RGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + W + + +A + YL ++H ++ NILL K+ Sbjct 439 EKQSQLDWTRRYKIIGGIARGILYLHQDSRLKIIHRDLKASNILLD-------ADMNPKI 491 Query 758 SDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 +D G+ + +++PE G S D + FG +LEI G Sbjct 492 ADFGLATIFGVEQTQGNTNRIAGTYAYMSPEYAMHG--QYSMKSDIYSFGVLVLEIIS-G 548 Query 812 EAPLQSRSPSEKE---HFYQRQHRLPEPSCP------------------QLATLTSQCLT 850 + E + RL P + + C+ Sbjct 549 KKNSGVYQMDETSTAGNLVTYASRLWRNKSPLELVDPTFGRNYQSNEVTRCIHIALLCVQ 608 Query 851 YEPTQRPSFRTILRD 865 P RP TI+ Sbjct 609 ENPEDRPMLSTIILM 623 >sp|Q9SY95|Y1155_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g61550 OS=Arabidopsis thaliana OX=3702 GN=At1g61550 PE=2 SV=1 Length=802 Score = 244 bits (622), Expect = 2e-66, Method: Composition-based stats. Identities = 75/308 (24%), Positives = 122/308 (40%), Gaps = 17/308 (6%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 + LG+G FG V G+ +AVK L + G Q + Sbjct 475 YFFEMKTIEIATNNFSLVNKLGQGGFGPVYKGKLQ-----DGKEIAVKRLSSSSG-QGKE 528 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLA 998 + EI ++ L H ++++ GCC + E+ LV E++ SL ++ R I Sbjct 529 EFMNEILLISKLQHINLVRILGCCIEGEER--LLVYEFMVNKSLDTFIFDSRKRVEIDWP 586 Query 999 QLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + Q I G+ YLH IHRD+ N+LLD+ KI DFGLA+ + EG +Y Sbjct 587 KRFSIIQGIARGLLYLHRDSRLRIIHRDVKVSNILLDDKMNPKISDFGLAR-MYEGTKYQ 645 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL-ELIGI 1114 + + +PE F SD +SFGV L E+++ S+ K L+ Sbjct 646 DNTRRIVGTLGYMSPEYAWTGVFSEKSDTYSFGVLLLEVISGEKISRFSYDKERKNLLAY 705 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 A L++ + C + + + RP L+ +L T + Sbjct 706 AWESWCENGGVGFLDKDATDSCHPSEVGRCVQIGLLCVQHQPADRPNTLELLSMLTTTSD 765 Query 1175 KYQGQAPS 1182 + P+ Sbjct 766 LPLPKEPT 773 Score = 233 bits (593), Expect = 1e-62, Method: Composition-based stats. Identities = 54/254 (21%), Positives = 95/254 (37%), Gaps = 45/254 (18%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 L ++ + + ++ LGQG VY+G+L+ Sbjct 467 KSEDVSGLYFFEMKTIEIATNNFSLVNKLGQGGFGPVYKGKLQDGK-------------- 512 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 + +K L S F L+S++ H +L + G C+ G E ++V Sbjct 513 -----------EIAVKRLSSSSGQGKEEFMNEILLISKLQHINLVRILGCCIEGEERLLV 561 Query 687 TEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNIL 741 E++ + LD ++ R V + W + + Q +A L YL ++H +V NIL Sbjct 562 YEFMVNKSLDTFIFDSRKRVEIDWPKRFSIIQGIARGLLYLHRDSRLRIIHRDVKVSNIL 621 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAM 795 L K+SD G+ + + V + +++PE G S Sbjct 622 LDDK-------MNPKISDFGLARMYEGTKYQDNTRRIVGTLGYMSPEYAWTGV--FSEKS 672 Query 796 DKWGFGATLLEICF 809 D + FG LLE+ Sbjct 673 DTYSFGVLLLEVIS 686 >sp|G5EGK5|CAM1_CAEEL Tyrosine-protein kinase receptor cam-1 OS=Caenorhabditis elegans OX=6239 GN=cam-1 PE=1 SV=1 Length=928 Score = 246 bits (627), Expect = 2e-66, Method: Composition-based stats. Identities = 94/319 (29%), Positives = 135/319 (42%), Gaps = 29/319 (9%) Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY-DPTNDGT 923 + + D + L +GEG FG V Y Sbjct 558 PMDQHLQQARRFPSQEPIDDNSYKVFEITPSQLSVREKIGEGQFGVVHSGIYTSGLFAPE 617 Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 VAVK + D R+ +QEI + T H ++IK G C + SL V EY+ Sbjct 618 PMAVAVKKCRHDATNAERAQLEQEIRAVATFDHPNVIKLIGVCY--MDNSLLAVFEYMVH 675 Query 984 GSLRDYLP------RHSIG-----LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032 G L + L H +G A+ L A QI GM YL + ++HRDLA RN L+ Sbjct 676 GDLHELLKVRVPPADHDMGGITEANAEFLYIATQIALGMEYLASMSFVHRDLATRNCLVG 735 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 + R +KI DFGL + G +YY++ PV W + E +++ +F ASDVWSFGVTL+ Sbjct 736 DTRTIKIADFGLMRT-SYGSDYYKMLHRSWMPVRWMSKEAIEQGRFSEASDVWSFGVTLW 794 Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152 E+ + + ++ EL+ L P CP +Y LM CW Sbjct 795 EIWSFGRQ--------------PYEGASNQQVIELVANRHLLECPHNCPTNIYSLMVECW 840 Query 1153 ETEASFRPTFENLIPILKT 1171 RPTF + L++ Sbjct 841 HENIERRPTFSEIRSRLQS 859 Score = 224 bits (571), Expect = 3e-59, Method: Composition-based stats. Identities = 73/374 (20%), Positives = 133/374 (36%), Gaps = 56/374 (15%) Query 510 QDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARA 569 + A+ + G S P + + ++ L P P + ++ AR Sbjct 517 ANSAYYRKLNGTSTPIMGRVPPHVEMTSLLPSAQHLGP----PPYPMDQH----LQQARR 568 Query 570 SPRTLNLSQLSFH--RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 P + S+ + +++ +G+G V+ G Sbjct 569 FPSQEPIDDNSYKVFEITPSQLSVREKIGEGQFGVVHSGI-------------------Y 609 Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYE-TASLMSQVSHTHLAFVHGVCVRGPENIMV 686 G + + V +K + A E ++ H ++ + GVC + V Sbjct 610 TSGLFAPEPMAVAVKKCRHDATNAERAQLEQEIRAVATFDHPNVIKLIGVCYMDNSLLAV 669 Query 687 TEYVEHGPLDVWLR-------RERGHVPMAWK--MVVAQQLASALSYLENKNLVHGNVCG 737 EY+ HG L L+ + G + A + +A Q+A + YL + + VH ++ Sbjct 670 FEYMVHGDLHELLKVRVPPADHDMGGITEANAEFLYIATQIALGMEYLASMSFVHRDLAT 729 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV------ERIPWLAPECLPGGANSL 791 RN L+ G + IK++D G+ + + + W++ E + G Sbjct 730 RNCLV-------GDTRTIKIADFGLMRTSYGSDYYKMLHRSWMPVRWMSKEAIEQG--RF 780 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCL 849 S A D W FG TL EI G P + S + +H L P + +L +C Sbjct 781 SEASDVWSFGVTLWEIWSFGRQPYEGASNQQVIELVANRHLLECPHNCPTNIYSLMVECW 840 Query 850 TYEPTQRPSFRTIL 863 +RP+F I Sbjct 841 HENIERRPTFSEIR 854 >sp|Q9I7F7|ACKL_DROME Activated Cdc42 kinase-like OS=Drosophila melanogaster OX=7227 GN=Ack-like PE=1 SV=3 Length=1337 Score = 249 bits (636), Expect = 2e-66, Method: Composition-based stats. Identities = 94/300 (31%), Positives = 146/300 (49%), Gaps = 27/300 (9%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 ++ + + + LG G FG V + N+ VA+K L + + + Sbjct 122 PNNKHIIPADSISVNKQLGTGEFGIVQQGVWSNGNER--IQVAIKCLCRERMQSNPMEFL 179 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-----GLAQL 1000 +E I+ ++ HE+I++ G SL LV E L SL + L + + L Sbjct 180 KEAAIMHSIEHENIVRLYGVVLATD--SLMLVTELAHLRSLLECLKDSGLRVSFLTIPTL 237 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 FA QIC GM YL + IHRDLAARN+L+ + VKI DFGL++A+ G +YY+ + Sbjct 238 CEFALQICNGMRYLEQKRLIHRDLAARNILVFSKDKVKISDFGLSRALGVGKDYYKTNFN 297 Query 1061 G--DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 P+ W APEC+ +F ASDVW+FGV L+E+ ++ Sbjct 298 VNLKLPIAWCAPECINYLRFTNASDVWAFGVCLWEMFSYGFQ--------------PWAA 343 Query 1119 MTVLRLTELLE--RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 +T L++ E ++ +RL +PD CP E Y LM CW+ +A+ RP F + L + + Sbjct 344 LTGLQILEAIDAPNYQRLEQPDCCPSEYYTLMMKCWQDDAAKRPRFGEIYDQLPDMKPEQ 403 Score = 215 bits (548), Expect = 1e-55, Method: Composition-based stats. Identities = 64/323 (20%), Positives = 116/323 (36%), Gaps = 48/323 (15%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 H + I+ LG G V +G + ++V + Sbjct 126 HIIPADSISVNKQLGTGEFGIVQQGVWSNG----------------------NERIQVAI 163 Query 642 KVLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + F + A++M + H ++ ++GV + ++VTE L L+ Sbjct 164 KCLCRERMQSNPMEFLKEAAIMHSIEHENIVRLYGVVLATDSLMLVTELAHLRSLLECLK 223 Query 701 RER---GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + + A Q+ + + YLE K L+H ++ RNIL+ + +K+ Sbjct 224 DSGLRVSFLTIPTLCEFALQICNGMRYLEQKRLIHRDLAARNILV-------FSKDKVKI 276 Query 758 SDPGVGLGALSREERVER---------IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 SD G+ ++ + I W APEC+ + A D W FG L E+ Sbjct 277 SDFGLSRALGVGKDYYKTNFNVNLKLPIAWCAPECI--NYLRFTNASDVWAFGVCLWEMF 334 Query 809 FDGEAPLQSRSPSEKEHF----YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 G P + + + ++ P+ + TL +C + +RP F I Sbjct 335 SYGFQPWAALTGLQILEAIDAPNYQRLEQPDCCPSEYYTLMMKCWQDDAAKRPRFGEIYD 394 Query 865 DLTRLQPHNLADVLTVNPDSPAS 887 L ++P L V+ Sbjct 395 QLPDMKPEQLKAVVNCTEPKKDH 417 >sp|P53668|LIMK1_MOUSE LIM domain kinase 1 OS=Mus musculus OX=10090 GN=Limk1 PE=1 SV=1 Length=647 Score = 240 bits (613), Expect = 2e-66, Method: Composition-based stats. Identities = 75/309 (24%), Positives = 132/309 (43%), Gaps = 33/309 (11%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 +F L LG+G FG+ T+ TGE++ +K L + + + Sbjct 328 CRPHRIFRPSDLIHGEVLGKGCFGQ----AIKVTHRETGEVMVMKEL-IRFDEETQRTFL 382 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLF 1003 +E+ ++R L H +++K+ G +K L + EY+ G+LR + +Q + F Sbjct 383 KEVKVMRCLEHPNVLKFIGVLYK--DKRLNFITEYIKGGTLRGIIKNMDSQYPWSQRVSF 440 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY-------- 1055 A+ I GMAYLH+ + IHRDL + N L+ +R V + DFGLA+ + + Sbjct 441 AKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLARLMIDEKNQSEDLRSLKK 500 Query 1056 ---RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 + R +W APE + + DV+SFG+ L E++ ++ + ++ Sbjct 501 PDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFG 560 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +G + P CP + + C + + RP+F L L+T+ Sbjct 561 LNVRGFLDRY-------------CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETL 607 Query 1173 HEKYQGQAP 1181 G P Sbjct 608 RMHLSGHLP 616 Score = 209 bits (531), Expect = 1e-55, Method: Composition-based stats. Identities = 67/350 (19%), Positives = 123/350 (35%), Gaps = 57/350 (16%) Query 547 LRRCCLPQPGETSNLII---MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603 LR C + TS+L R +L + ++ LG+G Sbjct 294 LRSCSIDTSPGTSSLASPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQA 353 Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663 + R G +V+K L + F + +M Sbjct 354 IKVTHRETGE------------------------VMVMKELIRFDEETQRTFLKEVKVMR 389 Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723 + H ++ GV + +TEY++ G L ++ P + ++ A+ +AS ++ Sbjct 390 CLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKNMDSQYPWSQRVSFAKDIASGMA 449 Query 724 YLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------------------G 765 YL + N++H ++ N L+ + + ++D G+ Sbjct 450 YLHSMNIIHRDLNSHNCLVRE-------NRNVVVADFGLARLMIDEKNQSEDLRSLKKPD 502 Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--FDGEAPLQSRSPSEK 823 R V W+APE + G S +D + FG L EI + + R+ Sbjct 503 RKKRYTVVGNPYWMAPEMING--RSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFG 560 Query 824 EHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 + R P+CP +T +C +P +RPSF + + L L+ H Sbjct 561 LNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETLRMH 610 >sp|Q54RR9|Y9844_DICDI Probable serine/threonine-protein kinase DDB_G0282963 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0282963 PE=3 SV=1 Length=1761 Score = 250 bits (638), Expect = 2e-66, Method: Composition-based stats. Identities = 71/281 (25%), Positives = 130/281 (46%), Gaps = 24/281 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G F KV Y GE+VA+K LK + + +K+E DIL + +++IK Sbjct 1481 KIGAGSFSKVYKAKYM------GEIVAIKVLKGEATSEQIELFKKEYDILSLVSSQNLIK 1534 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH- 1018 + G C+ EK L++V EY GSL + + I + + Q +G+ LH Sbjct 1535 FYGACK---EKKLRMVTEYCQHGSLYHIMSKRKMDISWPLVFKWMHQAVDGINSLHTMRP 1591 Query 1019 -YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRD+ ++N+L+++ +K+ DFGLAK + + APE Sbjct 1592 ALVHRDIKSQNLLINSQFDLKVADFGLAK---PTELQTGSNSTIKGTMAYCAPELYNGIS 1648 Query 1078 FYYASDVWSFGVTLYELLTHC--DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + +DV+S G+ L+E+ T Q P E+ + ++G R Sbjct 1649 YSEKADVYSLGIVLWEITTRVITGKYQRPYEDNTEI------SFDFQIVIMSSKQGIRPT 1702 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 P P ++ +L++ CW + + RP+ + ++ + ++++ Y Sbjct 1703 MPPNVPPKLSYLIQKCWNQDPNERPSCQQILLAITSLYDDY 1743 Score = 191 bits (484), Expect = 9e-48, Method: Composition-based stats. Identities = 64/318 (20%), Positives = 114/318 (36%), Gaps = 55/318 (17%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + ++ + +G G+ + VY+ + E V +KV Sbjct 1471 ISSTDLFLIKKIGAGSFSKVYKAKYMGE--------------------------IVAIKV 1504 Query 644 LDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 L + F + ++S VS +L +G C MVTEY +HG L + + Sbjct 1505 LKGEATSEQIELFKKEYDILSLVSSQNLIKFYGACKEKKLR-MVTEYCQHGSLYHIMSKR 1563 Query 703 RGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + + Q ++ L LVH ++ +N+L+ + +K++D Sbjct 1564 KMDISWPLVFKWMHQAVDGINSLHTMRPALVHRDIKSQNLLIN-------SQFDLKVADF 1616 Query 761 GVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF---DGEA 813 G+ L S + + APE G S S D + G L EI G+ Sbjct 1617 GLAKPTELQTGSNSTIKGTMAYCAPELYNG--ISYSEKADVYSLGIVLWEITTRVITGKY 1674 Query 814 PLQSRSPSEKEHFYQ---------RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 +E +Q + +P P+L+ L +C +P +RPS + IL Sbjct 1675 QRPYEDNTEISFDFQIVIMSSKQGIRPTMPPNVPPKLSYLIQKCWNQDPNERPSCQQILL 1734 Query 865 DLTRLQPHNLADVLTVNP 882 +T L + + N Sbjct 1735 AITSLYDDYIYNPSRYND 1752 >sp|Q8LKZ1|NORK_PEA Nodulation receptor kinase OS=Pisum sativum OX=3888 GN=NORK PE=1 SV=1 Length=924 Score = 246 bits (627), Expect = 2e-66, Method: Composition-based stats. Identities = 73/278 (26%), Positives = 127/278 (46%), Gaps = 18/278 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG FG V D G+ VAVK ++ Q + E+++L + HE+++ Sbjct 601 IGEGGFGSVYRGTLD-----DGQEVAVKV-RSATSTQGTREFDNELNLLSAIQHENLVPL 654 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHA- 1016 G C + ++ LV ++ GSL D L R + L A G+AYLH Sbjct 655 LGYCNEYDQQ--ILVYPFMSNGSLLDRLYGEPAKRKILDWPTRLSIALGAARGLAYLHTF 712 Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 + IHRD+ + N+LLD+ K+ DFG +K P+ + Y V + + PE K Sbjct 713 PGRSVIHRDVKSSNILLDHSMCAKVADFGFSKYAPQEGDSY-VSLEVRGTAGYLDPEYYK 771 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + SDV+SFGV L E+++ + P L+ A+ + ++ E+++ G + Sbjct 772 TQQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRVEWSLVEWAKPYIRASKVDEIVDPGIK 831 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + V + C E +++RP +++ L+ Sbjct 832 GGYHAEALWRVVEVALQCLEPYSTYRPCMVDIVRELED 869 Score = 215 bits (547), Expect = 4e-56, Method: Composition-based stats. Identities = 86/393 (22%), Positives = 134/393 (34%), Gaps = 101/393 (26%) Query 500 LRLRKFPIEQQDGAFVLEGWG-RSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGET 558 R R I LEG+G +++P + +L + DD F Sbjct 542 CRYRHKSI-------TLEGFGGKTYPMATNIIFSLP-----SKDDFF------------- 576 Query 559 SNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618 ++ P TL +L+ + + +G+G +VY G L Sbjct 577 -----IKSVSVKPFTLEYIELATEK-------YKTLIGEGGFGSVYRGTL---------- 614 Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678 D GQE V +KV + F +L+S + H +L + G C Sbjct 615 -------------DDGQE--VAVKVRSATSTQGTREFDNELNLLSAIQHENLVPLLGYCN 659 Query 679 RGPENIMVTEYVEHGPLDVWLRRE---RGHVPMAWKMVVAQQLASALSYLEN---KNLVH 732 + I+V ++ +G L L E R + ++ +A A L+YL ++++H Sbjct 660 EYDQQILVYPFMSNGSLLDRLYGEPAKRKILDWPTRLSIALGAARGLAYLHTFPGRSVIH 719 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPG 786 +V NILL S K++D G + E +L PE Sbjct 720 RDVKSSNILLDH-------SMCAKVADFGFSKYAPQEGDSYVSLEVRGTAGYLDPEYYKT 772 Query 787 GANSLSTAMDKWGFGATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCP-- 839 LS D + FG LLEI E P S E Y R ++ E P Sbjct 773 --QQLSEKSDVFSFGVVLLEIVSGREPLNIKRPRVEWSLVEWAKPYIRASKVDEIVDPGI 830 Query 840 ----------QLATLTSQCLTYEPTQRPSFRTI 862 ++ + QCL T RP I Sbjct 831 KGGYHAEALWRVVEVALQCLEPYSTYRPCMVDI 863 >sp|Q0WNY5|WAKLN_ARATH Wall-associated receptor kinase-like 18 OS=Arabidopsis thaliana OX=3702 GN=WAKL18 PE=2 SV=1 Length=793 Score = 243 bits (621), Expect = 3e-66, Method: Composition-based stats. Identities = 70/281 (25%), Positives = 118/281 (42%), Gaps = 22/281 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G G V G VAVK K + E+ IL + H H++K Sbjct 459 LGHGGQGTVYKGML-----VDGRTVAVKKSKV-IDEDKLQEFINEVVILSQINHRHVVKL 512 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQICEGMAYLHAQ 1017 GCC + + LV E++ G+L ++ +++ L A I ++YLH+ Sbjct 513 LGCCLET--EVPMLVYEFIINGNLFKHIHEEESDDYTMLWGMRLRIAVDIAGALSYLHSS 570 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 HRD+ + N+LLD K+ DFG +++V ++ V + PE + Sbjct 571 ASSPIYHRDIKSTNILLDEKYRAKVADFGTSRSVTIDQTHWTT--VISGTVGYVDPEYYQ 628 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG---QMTVLRLTELLERG 1131 ++ SDV+SFGV L EL+T D E++ +A+ M RLT++++ Sbjct 629 SSQYTEKSDVYSFGVILAELITG-DKPVIMVQNTQEIVALAEHFRVAMKEKRLTDIIDAR 687 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 R + V + C ++ RP + L+ + Sbjct 688 IRNDCKPEQVMAVAKVAMKCLSSKGKKRPNMREVFTELERI 728 Score = 221 bits (562), Expect = 1e-58, Method: Composition-based stats. Identities = 67/341 (20%), Positives = 125/341 (37%), Gaps = 68/341 (20%) Query 559 SNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618 L G R N +L + ++ LG G + VY+G L + Sbjct 426 QELNTREGYVEKTRVFNSRELEK---ATENFSENRVLGHGGQGTVYKGMLVDGRT----- 477 Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678 V +K D F ++SQ++H H+ + G C+ Sbjct 478 --------------------VAVKKSKVIDEDKLQEFINEVVILSQINHRHVVKLLGCCL 517 Query 679 RGPENIMVTEYVEHGPLDVWLRRERG-HVPMAW--KMVVAQQLASALSYLE---NKNLVH 732 ++V E++ +G L + E M W ++ +A +A ALSYL + + H Sbjct 518 ETEVPMLVYEFIINGNLFKHIHEEESDDYTMLWGMRLRIAVDIAGALSYLHSSASSPIYH 577 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGG 787 ++ NILL A K++D G + + ++ PE Sbjct 578 RDIKSTNILLDEKYRA-------KVADFGTSRSVTIDQTHWTTVISGTVGYVDPEYYQ-- 628 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-----EHFY--QRQHRLPEPSC-- 838 ++ + D + FG L E+ G+ P+ +++ EHF ++ RL + Sbjct 629 SSQYTEKSDVYSFGVILAELI-TGDKPVIMVQNTQEIVALAEHFRVAMKEKRLTDIIDAR 687 Query 839 ----------PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 +A + +CL+ + +RP+ R + +L R+ Sbjct 688 IRNDCKPEQVMAVAKVAMKCLSSKGKKRPNMREVFTELERI 728 >sp|P14616|INSRR_HUMAN Insulin receptor-related protein OS=Homo sapiens OX=9606 GN=INSRR PE=1 SV=2 Length=1297 Score = 249 bits (635), Expect = 3e-66, Method: Composition-based stats. Identities = 93/317 (29%), Positives = 149/317 (47%), Gaps = 32/317 (10%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT-GEMVAVKALK 933 D D + + IR+LG+G FG V G VA+K + Sbjct 957 NPEYFSASDMYVPDEWEVPREQISIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVN 1016 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991 P+ + +E +++ H+++ G QG+ +L ++ME + G L+ +L Sbjct 1017 ELASPRECIEFLKEASVMKAFKCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSHLRSL 1074 Query 992 ----RHSIGLAQ-----LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 ++ GL Q ++ A +I +GMAYL A ++HRDLAARN ++ D VKIGDF Sbjct 1075 RPEAENNPGLPQPALGEMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDF 1134 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 G+ + V E +YYR G PV W APE LK+ F SDVWSFGV L+E++T Sbjct 1135 GMTRDVYE-TDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVT------ 1187 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 L ++ ++ + + G L + CP ++ LM CW+ RP+F Sbjct 1188 --------LAEQPYQGLSNEQVLKFVMDGGVLEELEGCPLQLQELMSRCWQPNPRLRPSF 1239 Query 1163 ENLIPILKTVHEKYQGQ 1179 ++ L ++ E+ + Sbjct 1240 THI---LDSIQEELRPS 1253 Score = 241 bits (616), Expect = 7e-64, Method: Composition-based stats. Identities = 79/329 (24%), Positives = 129/329 (39%), Gaps = 51/329 (16%) Query 555 PGETSNLIIMRGARASPRTLNLSQL---SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 G+ N + A +P + S + V +++I+ + LGQG+ VYEG R Sbjct 944 YGKKRNRTLY--ASVNPEYFSASDMYVPDEWEVPREQISIIRELGQGSFGMVYEGLARGL 1001 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHL 670 +G+ + V LK ++ + + F + AS+M H+ Sbjct 1002 EAGE-------------------ESTPVALKTVNELASPRECIEFLKEASVMKAFKCHHV 1042 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP---------MAWKMVVAQQLASA 721 + GV +G +++ E + G L LR R + + +A ++A Sbjct 1043 VRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALGEMIQMAGEIADG 1102 Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------ 775 ++YL VH ++ RN ++++ +K+ D G+ + + Sbjct 1103 MAYLAANKFVHRDLAARNCMVSQ-------DFTVKIGDFGMTRDVYETDYYRKGGKGLLP 1155 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 + W+APE L G +T D W FG L EI E P Q S + F L E Sbjct 1156 VRWMAPESLKDGI--FTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEE 1213 Query 836 -PSCP-QLATLTSQCLTYEPTQRPSFRTI 862 CP QL L S+C P RPSF I Sbjct 1214 LEGCPLQLQELMSRCWQPNPRLRPSFTHI 1242 >sp|F1QVU0|LTK_DANRE Tyrosine-protein kinase receptor OS=Danio rerio OX=7955 GN=ltk PE=1 SV=1 Length=1530 Score = 249 bits (637), Expect = 3e-66, Method: Composition-based stats. Identities = 73/326 (22%), Positives = 116/326 (36%), Gaps = 40/326 (12%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S V +K IT L LG G VYEG++ Sbjct 923 SLSELKEVPRKNITLLRALGHGAFGEVYEGQVLGMN-------------------GENTA 963 Query 637 LRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 ++V +K L + F A +MS+ SH ++ GV ++ ++ E + G + Sbjct 964 MQVAIKTLPEICSEQDEMDFLMEALIMSKFSHQNIVRCIGVSLQILPRFILLELMTGGDM 1023 Query 696 DVWLRRERGHVP------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 +LR R M + +A+ +A YLE + +H ++ RN LL Sbjct 1024 KSFLRLNRPRTNHSSSLSMLELLHMARDIALGCRYLEENHFIHRDIAARNCLLT----CP 1079 Query 750 GTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGAT 803 G K+ D G+ + + W+ PE G + D W FG Sbjct 1080 GPDRVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPPEAFLEGI--FTCKTDTWSFGVL 1137 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP-QLATLTSQCLTYEPTQRPSFRT 861 L EI G P ++ E F R+ P SCP + + +QC + P RP+F T Sbjct 1138 LWEIFSLGYMPYPCKTNQEVLEFVTGGGRMDPPKSCPGPVYRIMTQCWQHCPEHRPNFTT 1197 Query 862 ILRDLTRLQPHNLADVLTVNPDSPAS 887 IL + + + Sbjct 1198 ILERINYCTQDPDVINTPLPVECGPP 1223 Score = 248 bits (633), Expect = 8e-66, Method: Composition-based stats. Identities = 93/344 (27%), Positives = 145/344 (42%), Gaps = 34/344 (10%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 Q P ++ + + + + S+ ++ + +R LG G FG+V Sbjct 893 QSPEYKLSKIRSSTIMTDYNPNYGYFGKAASLSELKEVPRKNITLLRALGHGAFGEVYEG 952 Query 915 CYDPTN-DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 N + T VA+K L C Q + E I+ H++I++ G + Sbjct 953 QVLGMNGENTAMQVAIKTLPEICSEQDEMDFLMEALIMSKFSHQNIVRCIGVSLQILPRF 1012 Query 974 LQLVMEYVPLGSLRDYLPRHS--------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 + L E + G ++ +L + + + +LL A+ I G YL H+IHRD+A Sbjct 1013 ILL--ELMTGGDMKSFLRLNRPRTNHSSSLSMLELLHMARDIALGCRYLEENHFIHRDIA 1070 Query 1026 ARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082 ARN LL DR+ KIGDFG+A+ + YYR PV W PE E F + Sbjct 1071 ARNCLLTCPGPDRVAKIGDFGMARDIYRA-SYYRKGGRAMLPVKWMPPEAFLEGIFTCKT 1129 Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 D WSFGV L+E+ + L + T + E + G R+ P CP Sbjct 1130 DTWSFGVLLWEIFS--------------LGYMPYPCKTNQEVLEFVTGGGRMDPPKSCPG 1175 Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 VY +M CW+ RP F + L+ ++ Y Q P V + Sbjct 1176 PVYRIMTQCWQHCPEHRPNFTTI---LERIN--YCTQDPDVINT 1214 >sp|C0LGL9|FEI2_ARATH LRR receptor-like serine/threonine-protein kinase FEI 2 OS=Arabidopsis thaliana OX=3702 GN=FEI2 PE=1 SV=1 Length=589 Score = 238 bits (608), Expect = 3e-66, Method: Composition-based stats. Identities = 67/313 (21%), Positives = 134/313 (43%), Gaps = 20/313 (6%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + AS + L + +G G FG V + G + A+K + Sbjct 285 MFHGDLPYASKDIIKKLESLNEEHIIGCGGFGTVYK-----LSMDDGNVFALKRI-VKLN 338 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--I 995 +++E++IL ++ H +++ +G C K L+ +Y+P GSL + L + + Sbjct 339 EGFDRFFERELEILGSIKHRYLVNLRGYCNSPTSK--LLLYDYLPGGSLDEALHKRGEQL 396 Query 996 GLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 + +G+AYLH + IHRD+ + N+LLD + ++ DFGLAK + + Sbjct 397 DWDSRVNIIIGAAKGLAYLHHDCSPRIIHRDIKSSNILLDGNLEARVSDFGLAKLLEDEE 456 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP-TKFLEL 1111 + + + APE ++ + +DV+SFGV + E+L+ + + K + Sbjct 457 SH--ITTIVAGTFGYLAPEYMQSGRATEKTDVYSFGVLVLEVLSGKLPTDASFIEKGFNI 514 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +G ++ R E+++ + + + C + RPT ++ +L++ Sbjct 515 VGWLNFLISENRAKEIVDLSCEG-VERESLDALLSIATKCVSSSPDERPTMHRVVQLLES 573 Query 1172 VHEKYQGQAPSVF 1184 + PS F Sbjct 574 ---EVMTPCPSDF 583 Score = 194 bits (492), Expect = 5e-51, Method: Composition-based stats. Identities = 65/374 (17%), Positives = 127/374 (34%), Gaps = 64/374 (17%) Query 535 GCLLRAGDDCFSLRRCCLPQPG-ETSNLIIMRGARASPRTLN--LSQLSFHRVDQ-KEIT 590 G LL CF E+ +L+I G AS + L S + + + + Sbjct 246 GGLLLVALMCFWGCFLYKKLGRVESKSLVIDVGGGASIVMFHGDLPYASKDIIKKLESLN 305 Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + +G G VY+ MDD + LK + + Sbjct 306 EEHIIGCGGFGTVYK-------------LSMDDGNVF------------ALKRIVKLNEG 340 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 F ++ + H +L + G C +++ +Y+ G LD L + + Sbjct 341 FDRFFERELEILGSIKHRYLVNLRGYCNSPTSKLLLYDYLPGGSLDEALHKRGEQLDWDS 400 Query 711 KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 ++ + A L+YL + ++H ++ NILL + ++SD G+ Sbjct 401 RVNIIIGAAKGLAYLHHDCSPRIIHRDIKSSNILLD-------GNLEARVSDFGLAKLLE 453 Query 768 SREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 E + +LAPE + G + D + FG +LE+ G+ P + + Sbjct 454 DEESHITTIVAGTFGYLAPEYMQSGRA--TEKTDVYSFGVLVLEVLS-GKLPTDASFIEK 510 Query 823 KEHFYQRQHRL-----------------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + + L S L ++ ++C++ P +RP+ +++ Sbjct 511 GFNIVGWLNFLISENRAKEIVDLSCEGVERESLDALLSIATKCVSSSPDERPTMHRVVQL 570 Query 866 LTRLQPHNLADVLT 879 L Sbjct 571 LESEVMTPCPSDFY 584 >sp|A7J1T0|M313B_XENLA Mitogen-activated protein kinase kinase kinase 13-B OS=Xenopus laevis OX=8355 GN=map3k13-b PE=2 SV=1 Length=961 Score = 246 bits (627), Expect = 3e-66, Method: Composition-based stats. Identities = 84/301 (28%), Positives = 126/301 (42%), Gaps = 35/301 (12%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + + + + D + +++ LG G G V L + GE VA+K Sbjct 145 WNIIGKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFR------GEEVAIK 198 Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 + R + +I LR L H +II +KG C ++MEY G L + L Sbjct 199 KV--------REQKETDIKHLRKLKHPNIIAFKGVCTQA--PCYCILMEYCAQGQLYEVL 248 Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 + L+ ++ I GM YLH IHRDL + NVL+ + VKI DFG +K + Sbjct 249 RAGRKVTPKLLVEWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHADTVKISDFGTSKELS 308 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 + + V W APE ++ D+WSFGV L+ELLT P K + Sbjct 309 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVLLWELLTG-----EIPYKDV 359 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + I G + LP P CP LMK W+++ RP+F ++ L Sbjct 360 DSSAIIWGVGSN---------SLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQILMHL 410 Query 1170 K 1170 Sbjct 411 D 411 Score = 218 bits (556), Expect = 4e-57, Method: Composition-based stats. Identities = 78/390 (20%), Positives = 133/390 (34%), Gaps = 60/390 (15%) Query 484 ILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDD 543 ++ R Q + + LR + P G G + + ++ +G+ Sbjct 72 SISEDSRDQFENSVLQLRDQDEPENTAPQGSSHSGDGGNNSANEDIRIHFSRSRSGSGNG 131 Query 544 CFS--LRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRT 601 F L C P + +A L Q V +EI++L LG G + Sbjct 132 GFLEGLFGCLRP--------VWNIIGKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQG 183 Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL 661 V+ G+ R E V +K + Sbjct 184 AVFLGKFRGE--------------------------EVAIKKVREQKE-------TDIKH 210 Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA 721 + ++ H ++ GVC + P ++ EY G L LR R P + + +AS Sbjct 211 LRKLKHPNIIAFKGVCTQAPCYCILMEYCAQGQLYEVLRAGRKVTP-KLLVEWSTGIASG 269 Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV---ERIPW 778 ++YL ++H ++ N+L+ + +K+SD G + ++ + W Sbjct 270 MNYLHLHKIIHRDLKSPNVLVTH-------ADTVKISDFGTSKELSDKSTKMSFAGTVAW 322 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPE 835 +APE + +S +D W FG L E+ GE P + S +P Sbjct 323 MAPEVIRN--EPVSEKVDIWSFGVLLWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPS 379 Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 L Q +P RPSFR IL Sbjct 380 TCPDGFKILMKQTWQSKPRNRPSFRQILMH 409 >sp|C0LGL4|Y2289_ARATH Probable LRR receptor-like serine/threonine-protein kinase At2g28960 OS=Arabidopsis thaliana OX=3702 GN=At2g28960 PE=1 SV=1 Length=880 Score = 244 bits (624), Expect = 4e-66, Method: Composition-based stats. Identities = 72/316 (23%), Positives = 129/316 (41%), Gaps = 17/316 (5%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 H L + ++ + + R LGEG FG V + T + +AVK Sbjct 547 QHGLPNRPSIFTQTKRFTYSEVEALTDNFERVLGEGGFGVVYHGILNGT-----QPIAVK 601 Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 L + Q +K E+++L ++H +++ G C++ E +L L+ EY P G L+ +L Sbjct 602 -LLSQSSVQGYKEFKAEVELLLRVHHVNLVSLVGYCDE--ESNLALLYEYAPNGDLKQHL 658 Query 991 PRH----SIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 + + L + +G+ YLH +HRD+ N+LLD K+ DFG Sbjct 659 SGERGGSPLKWSSRLKIVVETAQGLEYLHTGCKPPMVHRDVKTTNILLDEHFQAKLADFG 718 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 L+++ P G E + +P + PE + + SDV+SFG+ L E++T Q Sbjct 719 LSRSFPVGGETHVSTAVAGTP-GYLDPEYYRTNRLNEKSDVYSFGIVLLEIITSRPVIQQ 777 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163 K + +T + +++ + + +C + RPT Sbjct 778 TREK-PHIAAWVGYMLTKGDIENVVDPRLNRDYEPTSVWKALEIAMSCVNPSSEKRPTMS 836 Query 1164 NLIPILKTVHEKYQGQ 1179 + LK + Sbjct 837 QVTNELKQCLTLENSK 852 Score = 212 bits (539), Expect = 3e-55, Method: Composition-based stats. Identities = 71/347 (20%), Positives = 115/347 (33%), Gaps = 68/347 (20%) Query 554 QPGETSNLIIMRGARASPRTL--NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 +P + +L ++ + ++ + ++ V+ LG+G VY G L Sbjct 536 RPTQVDSLPTVQHGLPNRPSIFTQTKRFTYSEVEALTDNFERVLGEGGFGVVYHGILNGT 595 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 + +K+L S F L+ +V H +L Sbjct 596 QP-------------------------IAVKLLSQSSVQGYKEFKAEVELLLRVHHVNLV 630 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE--- 726 + G C ++ EY +G L L ERG P+ W ++ + + A L YL Sbjct 631 SLVGYCDEESNLALLYEYAPNGDLKQHLSGERGGSPLKWSSRLKIVVETAQGLEYLHTGC 690 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERV-----ERIPWLA 780 +VH +V NILL KL+D G+ + E V +L Sbjct 691 KPPMVHRDVKTTNILLDE-------HFQAKLADFGLSRSFPVGGETHVSTAVAGTPGYLD 743 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR----------- 829 PE N L+ D + FG LLEI Q+R EK H Sbjct 744 PEYYRT--NRLNEKSDVYSFGIVLLEIITSRPVIQQTR---EKPHIAAWVGYMLTKGDIE 798 Query 830 ---QHRLPEPSCPQLA----TLTSQCLTYEPTQRPSFRTILRDLTRL 869 RL P + C+ +RP+ + +L + Sbjct 799 NVVDPRLNRDYEPTSVWKALEIAMSCVNPSSEKRPTMSQVTNELKQC 845 >sp|O59790|ARK1_SCHPO Serine/threonine-protein kinase ark1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ark1 PE=1 SV=2 Length=355 Score = 231 bits (588), Expect = 4e-66, Method: Composition-based stats. Identities = 68/283 (24%), Positives = 111/283 (39%), Gaps = 29/283 (10%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGW 944 FH + + LG+G FG+V L TG +VA+K L + Sbjct 79 PQWREFHIGMFEIGKPLGKGKFGRVYL----AKEKKTGFIVALKTLHKSELVQSKIEKQV 134 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLF 1003 ++EI+I L H++I++ G D EK + L++E+ G L +L R + Sbjct 135 RREIEIQSNLRHKNILRLYGHFHD--EKRIYLILEFAGRGELYQHLRRAKRFSEEVASKY 192 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 Q+ ++YLH +H IHRD+ N+LL D +K+ DFG + P R Sbjct 193 IFQMANALSYLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNR-----RTTLCG 247 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 + + PE ++ + D+WS GV YE L + IA+ Sbjct 248 TLDYLPPEMVEGKEHTEKVDLWSLGVLTYEFLVGAPPFEDMSGHSATYKRIAKVD----- 302 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L P P + L+ + R + E ++ Sbjct 303 ----------LKIPSFVPPDARDLISRLLQHNPEKRMSLEQVM 335 Score = 197 bits (502), Expect = 1e-54, Method: Composition-based stats. Identities = 64/290 (22%), Positives = 102/290 (35%), Gaps = 42/290 (14%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS- 647 LG+G VY + + G V LK L S Sbjct 89 FEIGKPLGKGKFGRVYLAKEKKTGF------------------------IVALKTLHKSE 124 Query 648 --HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 I + S + H ++ ++G ++ E+ G L LRR + Sbjct 125 LVQSKIEKQVRREIEIQSNLRHKNILRLYGHFHDEKRIYLILEFAGRGELYQHLRRAK-R 183 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 Q+A+ALSYL K+++H ++ NILL G IKLSD G + Sbjct 184 FSEEVASKYIFQMANALSYLHKKHVIHRDIKPENILL-------GIDGEIKLSDFGWSVH 236 Query 766 ALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 A S R + +L PE + G + +D W G E G P + S Sbjct 237 APSNRRTTLCGTLDYLPPEMVEG--KEHTEKVDLWSLGVLTYEFLV-GAPPFEDMSGHSA 293 Query 824 --EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 + + ++P P L S+ L + P +R S ++R ++ Sbjct 294 TYKRIAKVDLKIPSFVPPDARDLISRLLQHNPEKRMSLEQVMRHPWIVKY 343 >sp|O61125|STK4_DICDI Serine/threonine-protein kinase 4 homolog A OS=Dictyostelium discoideum OX=44689 GN=krsA PE=1 SV=1 Length=461 Score = 234 bits (597), Expect = 4e-66, Method: Composition-based stats. Identities = 67/292 (23%), Positives = 129/292 (44%), Gaps = 25/292 (9%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 ++ + +++ + LGEG +G V Y N TG +VA+K + D Sbjct 1 MSTLNVPKETMSRKDPEKFFTIVEKLGEGSYGSV----YKAINISTGIVVAIKKVSVD-- 54 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD--YLPRHSI 995 ++EI ++ +I+ Y + E + +VME+ GS+ D + ++ Sbjct 55 -NDLEDMEKEISFMKQCKSPYIVTYYASFRKENE--VWIVMEHCGAGSVCDAMKITDKTL 111 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 Q+ + ++ + +G+AYLH+ IHRD+ A N+L+++ K+ DFG++ + + Sbjct 112 SEDQIAVVSRDVLQGLAYLHSVRKIHRDIKAGNILMNHKGESKLADFGVSGQLSDTMA-- 169 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 R+ FW APE ++E + Y +D+WS+G+T E+ + PP + Sbjct 170 -KRQTVIGTPFWMAPEVIQEIGYDYKADIWSYGITCIEM-----AESKPP------LFNV 217 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + +L P+K E + C + RP+ E L+ Sbjct 218 HPMRVIFMIPNPSRPPPKLTEPEKWSPEFNDFLAKCLTRKPELRPSAEELLK 269 Score = 191 bits (485), Expect = 3e-51, Method: Composition-based stats. Identities = 60/307 (20%), Positives = 113/307 (37%), Gaps = 47/307 (15%) Query 572 RTLNLSQLSFHRVDQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 TLN+ + + R D ++ T + LG+G+ +VY+ G Sbjct 2 STLNVPKETMSRKDPEKFFTIVEKLGEGSYGSVYKAINISTG------------------ 43 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 + V +K + + + + S M Q ++ + + E +V E+ Sbjct 44 ------IVVAIKKVSVDNDLEDME--KEISFMKQCKSPYIVTYYASFRKENEVWIVMEHC 95 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G + ++ + VV++ + L+YL + +H ++ NIL+ G + Sbjct 96 GAGSVCDAMKITDKTLSEDQIAVVSRDVLQGLAYLHSVRKIHRDIKAGNILMNHKGES-- 153 Query 751 TSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 KL+D G + R+ + W+APE + D W +G T +E Sbjct 154 -----KLADFGVSGQLSDTMAKRQTVIGTPFWMAPEVIQEIGYDY--KADIWSYGITCIE 206 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRL------PEPSCPQLATLTSQCLTYEPTQRPSFR 860 + + PL + P R PE P+ ++CLT +P RPS Sbjct 207 MAES-KPPLFNVHPMRVIFMIPNPSRPPPKLTEPEKWSPEFNDFLAKCLTRKPELRPSAE 265 Query 861 TILRDLT 867 +L+ Sbjct 266 ELLKHPF 272 >sp|Q94AG2|SERK1_ARATH Somatic embryogenesis receptor kinase 1 OS=Arabidopsis thaliana OX=3702 GN=SERK1 PE=1 SV=2 Length=625 Score = 239 bits (610), Expect = 4e-66, Method: Composition-based stats. Identities = 69/279 (25%), Positives = 119/279 (43%), Gaps = 20/279 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FGKV G +VAVK LK + P ++ E++++ H ++++ Sbjct 308 LGRGGFGKVYKGRL-----ADGTLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRL 362 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ 1017 +G C E+ LV Y+ GS+ L + A G++YLH Sbjct 363 RGFCMTPTER--LLVYPYMANGSVASCLRERPPSQPPLDWPTRKRIALGSARGLSYLHDH 420 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRD+ A N+LLD + +GDFGLAK + + V + APE L Sbjct 421 CDPKIIHRDVKAANILLDEEFEAVVGDFGLAKLMDYKDTH--VTTAVRGTIGHIAPEYLS 478 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 K +DV+ +G+ L EL+T + + + L+ +G + +L L++ Sbjct 479 TGKSSEKTDVFGYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEMLVDPD 538 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + ++ +V + C + RP ++ +L+ Sbjct 539 LQTNYEERELEQVIQVALLCTQGSPMERPKMSEVVRMLE 577 Score = 196 bits (497), Expect = 2e-51, Method: Composition-based stats. Identities = 69/324 (21%), Positives = 109/324 (34%), Gaps = 67/324 (21%) Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + S V + + LG+G VY+GRL Sbjct 286 QLKRFSLRELQVASDGFSNKNILGRGGFGKVYKGRLADG--------------------- 324 Query 633 RGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 V +K L L F ++S H +L + G C+ E ++V Y+ Sbjct 325 ----TLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMA 380 Query 692 HGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745 +G + LR R P+ W + +A A LSYL + ++H +V NILL Sbjct 381 NGSVASCLRERPPSQPPLDWPTRKRIALGSARGLSYLHDHCDPKIIHRDVKAANILLDEE 440 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800 A + D G+ ++ V I +APE L G + S D +G+ Sbjct 441 FEAV-------VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 491 Query 801 GATLLEICFDGEAPLQSR--SPSEKEHFYQRQHRLPEPSCPQLAT--------------- 843 G LLE+ A +R + + + L E L Sbjct 492 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEMLVDPDLQTNYEERELEQV 551 Query 844 --LTSQCLTYEPTQRPSFRTILRD 865 + C P +RP ++R Sbjct 552 IQVALLCTQGSPMERPKMSEVVRM 575 >sp|P43405|KSYK_HUMAN Tyrosine-protein kinase SYK OS=Homo sapiens OX=9606 GN=SYK PE=1 SV=1 Length=635 Score = 239 bits (610), Expect = 4e-66, Method: Composition-based stats. Identities = 101/325 (31%), Positives = 144/325 (44%), Gaps = 23/325 (7%) Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY--LKKIRDLGEGHF 908 YEP P L V+ R + ++LG G+F Sbjct 323 YEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNF 382 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 G V Y V + LK + P + E ++++ L + +I++ G CE Sbjct 383 GTVKKGYYQMKKVVKTVAVKI--LKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICE 440 Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 +S LVME LG L YL ++ + ++ Q+ GM YL +++HRDLAA Sbjct 441 ---AESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAA 497 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RNVLL KI DFGL+KA+ YY+ + G PV WYAPEC+ YKF SDVWS Sbjct 498 RNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWS 557 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 FGV ++E ++ M +T +LE+GER+ P CP E+Y Sbjct 558 FGVLMWEAFSYGQK--------------PYRGMKGSEVTAMLEKGERMGCPAGCPREMYD 603 Query 1147 LMKNCWETEASFRPTFENLIPILKT 1171 LM CW + RP F + L+ Sbjct 604 LMNLCWTYDVENRPGFAAVELRLRN 628 Score = 207 bits (528), Expect = 2e-55, Method: Composition-based stats. Identities = 66/290 (23%), Positives = 114/290 (39%), Gaps = 40/290 (14%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + LG G V +G +++ K+ + P LK Sbjct 373 EDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDP----------ALK-------- 414 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 A++M Q+ + ++ + G+C ++V E E GPL+ +L++ R HV Sbjct 415 --DELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNR-HVKDKN 470 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + + Q++ + YLE N VH ++ RN+LL T + K+SD G+ + E Sbjct 471 IIELVHQVSMGMKYLEESNFVHRDLAARNVLL-------VTQHYAKISDFGLSKALRADE 523 Query 771 ERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + + W APEC+ S+ D W FG + E G+ P + SE Sbjct 524 NYYKAQTHGKWPVKWYAPECI--NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEV 581 Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 ++ R+ P ++ L + C TY+ RP F + L Sbjct 582 TAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYY 631 Score = 37.7 bits (86), Expect = 0.80, Method: Composition-based stats. Identities = 19/101 (19%), Positives = 34/101 (34%), Gaps = 15/101 (15%) Query 453 GPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQ 509 G + + L DGLYL+ S ++ L+VA +A + IE+ Sbjct 18 GNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKA---------HHYTIER 68 Query 510 QDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRC 550 + GR+ S +L + L++ Sbjct 69 ELNGTYAIAGGRTHASPADL---CHYHSQESDGLVCLLKKP 106 >sp|P55245|EGFR_MACMU Epidermal growth factor receptor OS=Macaca mulatta OX=9544 GN=EGFR PE=2 SV=2 Length=1210 Score = 248 bits (633), Expect = 4e-66, Method: Composition-based stats. Identities = 91/272 (33%), Positives = 134/272 (49%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + VA+K L+ P+ E ++ ++ + H+ + Sbjct 718 LGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRL 777 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C +QL+ + +P G L DY+ H IG LL + QI +GM YL + + Sbjct 778 LGICLTST---VQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLV 834 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ + VKI DFGLAK + + Y E G P+ W A E + + + Sbjct 835 HRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHA-EGGKVPIKWMALESILHRIYTH 893 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + ++ +LE+GERLP+P C Sbjct 894 QSDVWSYGVTVWELMTFGSK--------------PYDGIPASEISSILEKGERLPQPPIC 939 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW +A RP F LI + Sbjct 940 TIDVYMIMVKCWMIDADSRPKFRELIIEFSKM 971 Score = 222 bits (565), Expect = 8e-58, Method: Composition-based stats. Identities = 67/337 (20%), Positives = 133/337 (39%), Gaps = 39/337 (12%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P +Q + + E ++ LG G VY+G EG Sbjct 693 TPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKV-------------- 738 Query 630 GRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ V +K L + + A +M+ V + H+ + G+C+ ++T+ Sbjct 739 ------KIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQ-LITQ 791 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + G L ++R + ++ + + Q+A ++YLE++ LVH ++ RN+L+ Sbjct 792 LMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLV------ 845 Query 749 EGTSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGA 802 T +K++D G+ LGA +E E I W+A E + + D W +G Sbjct 846 -KTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRI--YTHQSDVWSYGV 902 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860 T+ E+ G P SE ++ RLP+P + + +C + RP FR Sbjct 903 TVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFR 962 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897 ++ + +++ ++ + Y Sbjct 963 ELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYR 999 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens OX=9606 GN=EGFR PE=1 SV=2 Length=1210 Score = 248 bits (633), Expect = 4e-66, Method: Composition-based stats. Identities = 91/272 (33%), Positives = 134/272 (49%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + VA+K L+ P+ E ++ ++ + H+ + Sbjct 718 LGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRL 777 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C +QL+ + +P G L DY+ H IG LL + QI +GM YL + + Sbjct 778 LGICLTST---VQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLV 834 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ + VKI DFGLAK + + Y E G P+ W A E + + + Sbjct 835 HRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHA-EGGKVPIKWMALESILHRIYTH 893 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + ++ +LE+GERLP+P C Sbjct 894 QSDVWSYGVTVWELMTFGSK--------------PYDGIPASEISSILEKGERLPQPPIC 939 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW +A RP F LI + Sbjct 940 TIDVYMIMVKCWMIDADSRPKFRELIIEFSKM 971 Score = 222 bits (565), Expect = 8e-58, Method: Composition-based stats. Identities = 67/337 (20%), Positives = 133/337 (39%), Gaps = 39/337 (12%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P +Q + + E ++ LG G VY+G EG Sbjct 693 TPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKV-------------- 738 Query 630 GRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ V +K L + + A +M+ V + H+ + G+C+ ++T+ Sbjct 739 ------KIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQ-LITQ 791 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + G L ++R + ++ + + Q+A ++YLE++ LVH ++ RN+L+ Sbjct 792 LMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLV------ 845 Query 749 EGTSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGA 802 T +K++D G+ LGA +E E I W+A E + + D W +G Sbjct 846 -KTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRI--YTHQSDVWSYGV 902 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860 T+ E+ G P SE ++ RLP+P + + +C + RP FR Sbjct 903 TVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFR 962 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897 ++ + +++ ++ + Y Sbjct 963 ELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYR 999 >sp|Q9WTL4|INSRR_MOUSE Insulin receptor-related protein OS=Mus musculus OX=10090 GN=Insrr PE=1 SV=2 Length=1300 Score = 248 bits (634), Expect = 4e-66, Method: Composition-based stats. Identities = 95/329 (29%), Positives = 154/329 (47%), Gaps = 36/329 (11%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT-GEMVAV 929 ++ D + + IR+LG+G FG V G VA+ Sbjct 953 YTSVNPEYFSASHMYVPDEWEVPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVAL 1012 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K + + R + +E +++ H+++ G QG+ +L ++ME + G L+ + Sbjct 1013 KTVNELASARERVEFLKEASVMKAFKCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSH 1070 Query 990 LP------RHSIGLAQ-----LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 L ++ GL Q ++ A +I +GMAYL A+ ++HRDLAARN ++ D VK Sbjct 1071 LRSLRPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQDFTVK 1130 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 IGDFG+ + V E +YYR G PV W APE LK+ F SDVWSFGV L+E++T Sbjct 1131 IGDFGMTRDVYE-TDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVT-- 1187 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 L ++ ++ + + G L + CP ++ LM+ CW+ Sbjct 1188 ------------LAEQPYQGLSNEQVLKFVMDGGVLEELENCPIQLQELMRLCWQHSPRL 1235 Query 1159 RPTFENLIPILKTVHEKYQGQAPSVFSVC 1187 RPTF + IL + ++ + F +C Sbjct 1236 RPTF---VHILDRIQDELRPS----FRLC 1257 Score = 240 bits (612), Expect = 2e-63, Method: Composition-based stats. Identities = 74/324 (23%), Positives = 123/324 (38%), Gaps = 46/324 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 V +++I + LGQG+ VYEG R +G+ + V L Sbjct 972 WEVPREQIAIIRELGQGSFGMVYEGLARGLEAGE-------------------ESTPVAL 1012 Query 642 KVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K ++ + + F + AS+M H+ + GV +G +++ E + G L LR Sbjct 1013 KTVNELASARERVEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLR 1072 Query 701 RERGHVP---------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 R ++ + +A ++A ++YL K VH ++ RN ++++ Sbjct 1073 SLRPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQ------- 1125 Query 752 SPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLL 805 +K+ D G+ + + + W+APE L G +T D W FG L Sbjct 1126 DFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGI--FTTHSDVWSFGVVLW 1183 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPE-PSCP-QLATLTSQCLTYEPTQRPSFRTIL 863 EI E P Q S + F L E +CP QL L C + P RP+F IL Sbjct 1184 EIVTLAEQPYQGLSNEQVLKFVMDGGVLEELENCPIQLQELMRLCWQHSPRLRPTFVHIL 1243 Query 864 RDLTRLQPHNLADVLTVNPDSPAS 887 + + Sbjct 1244 DRIQDELRPSFRLCSFYYSPECQR 1267 >sp|P70424|ERBB2_MOUSE Receptor tyrosine-protein kinase erbB-2 OS=Mus musculus OX=10090 GN=Erbb2 PE=1 SV=3 Length=1256 Score = 248 bits (633), Expect = 4e-66, Method: Composition-based stats. Identities = 87/272 (32%), Positives = 133/272 (49%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + VA+K L+ + P+ E ++ + ++ + Sbjct 727 LGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRL 786 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C +QLV + +P G L D++ H +G LL + QI +GM+YL + Sbjct 787 LGICLTST---VQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVRLV 843 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W A E + +F + Sbjct 844 HRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWMALESILRRRFTH 902 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + + +LLE+GERLP+P C Sbjct 903 QSDVWSYGVTVWELMTFG--------------AKPYDGIPAREIPDLLEKGERLPQPPIC 948 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW ++ RP F L+ + Sbjct 949 TIDVYMIMVKCWMIDSECRPRFRELVSEFSRM 980 Score = 222 bits (565), Expect = 1e-57, Method: Composition-based stats. Identities = 69/335 (21%), Positives = 127/335 (38%), Gaps = 39/335 (12%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P +Q + + E+ +L LG G VY+G +G Sbjct 702 TPSGAVPNQAQMRILKETELRKLKVLGSGAFGTVYKGIWIPDGENV-------------- 747 Query 630 GRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ V +KVL + + A +M+ V +++ + G+C+ +VT+ Sbjct 748 ------KIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQ 800 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + +G L +R RG + + Q+A +SYLE LVH ++ RN+L+ Sbjct 801 LMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVRLVHRDLAARNVLVKSPN-- 858 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 +K++D G+ + I W+A E + + D W +G Sbjct 859 -----HVKITDFGLARLLDIDETEYHADGGKVPIKWMALESIL--RRRFTHQSDVWSYGV 911 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860 T+ E+ G P E ++ RLP+P + + +C + RP FR Sbjct 912 TVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFR 971 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895 ++ + +R+ V+ N D S P Sbjct 972 ELVSEFSRMARDPQRFVVIQNEDLGPSSPMDSTFY 1006 >sp|C0LGV0|Y5487_ARATH Probable LRR receptor-like serine/threonine-protein kinase At5g48740 OS=Arabidopsis thaliana OX=3702 GN=At5g48740 PE=1 SV=1 Length=895 Score = 244 bits (623), Expect = 5e-66, Method: Composition-based stats. Identities = 74/303 (24%), Positives = 121/303 (40%), Gaps = 19/303 (6%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + S +G G FG V G+ VAVK + D Sbjct 587 MQNWNASRIFSHKEIKSATRNFKEVIGRGSFGAVYRG-----KLPDGKQVAVKV-RFDRT 640 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PR 992 + E+ +L + H++++ ++G C + + LV EY+ GSL D+L R Sbjct 641 QLGADSFINEVHLLSQIRHQNLVSFEGFCYEPKRQ--ILVYEYLSGGSLADHLYGPRSKR 698 Query 993 HSIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 HS+ L A +G+ YLH IHRD+ + N+LLD D K+ DFGL+K Sbjct 699 HSLNWVSRLKVAVDAAKGLDYLHNGSEPRIIHRDVKSSNILLDKDMNAKVSDFGLSKQFT 758 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKF 1108 + + + + PE + SDV+SFGV L EL+ + S S Sbjct 759 KADASH-ITTVVKGTAGYLDPEYYSTLQLTEKSDVYSFGVVLLELICGREPLSHSGSPDS 817 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 L+ A+ + E+++ + + + C +AS RP+ ++ Sbjct 818 FNLVLWARPNLQAGAF-EIVDDILKETFDPASMKKAASIAIRCVGRDASGRPSIAEVLTK 876 Query 1169 LKT 1171 LK Sbjct 877 LKE 879 Score = 207 bits (528), Expect = 6e-54, Method: Composition-based stats. Identities = 69/351 (20%), Positives = 107/351 (30%), Gaps = 49/351 (14%) Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587 + + G L A F + I R S + Sbjct 546 AILLGVSGGALFATFLVFVFMS-IFTRRQRNKERDITRAQLKMQNWNASRIFSHKEIKSA 604 Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 +G+G+ VY G+L +V +KV Sbjct 605 TRNFKEVIGRGSFGAVYRGKLPDGK-------------------------QVAVKVRFDR 639 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---RRERG 704 A +F L+SQ+ H +L G C I+V EY+ G L L R +R Sbjct 640 TQLGADSFINEVHLLSQIRHQNLVSFEGFCYEPKRQILVYEYLSGGSLADHLYGPRSKRH 699 Query 705 HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 + ++ VA A L YL N ++H +V NILL + K+SD G Sbjct 700 SLNWVSRLKVAVDAAKGLDYLHNGSEPRIIHRDVKSSNILLDK-------DMNAKVSDFG 752 Query 762 VGLGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 + +L PE L+ D + FG LLE+ E Sbjct 753 LSKQFTKADASHITTVVKGTAGYLDPEYYST--LQLTEKSDVYSFGVVLLELICGREPLS 810 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 S SP + L + + + + T++P +I Sbjct 811 HSGSPDSFNLVLWARPNLQAGAFEIVDDILKE--TFDPASMKKAASIAIRC 859 >sp|Q01279|EGFR_MOUSE Epidermal growth factor receptor OS=Mus musculus OX=10090 GN=Egfr PE=1 SV=1 Length=1210 Score = 248 bits (632), Expect = 5e-66, Method: Composition-based stats. Identities = 91/272 (33%), Positives = 134/272 (49%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + VA+K L+ P+ E ++ ++ + H+ + Sbjct 720 LGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRL 779 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C +QL+ + +P G L DY+ H IG LL + QI +GM YL + + Sbjct 780 LGICLTST---VQLITQLMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLV 836 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ + VKI DFGLAK + + Y E G P+ W A E + + + Sbjct 837 HRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHA-EGGKVPIKWMALESILHRIYTH 895 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + ++ +LE+GERLP+P C Sbjct 896 QSDVWSYGVTVWELMTFGSK--------------PYDGIPASDISSILEKGERLPQPPIC 941 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW +A RP F LI + Sbjct 942 TIDVYMIMVKCWMIDADSRPKFRELILEFSKM 973 Score = 224 bits (571), Expect = 2e-58, Method: Composition-based stats. Identities = 66/345 (19%), Positives = 136/345 (39%), Gaps = 39/345 (11%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P +Q + + E ++ LG G VY+G EG Sbjct 695 TPSGEAPNQAHLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKV-------------- 740 Query 630 GRDRGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ V +K L + + A +M+ V + H+ + G+C+ ++T+ Sbjct 741 ------KIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQ-LITQ 793 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + +G L ++R + ++ + + Q+A ++YLE++ LVH ++ RN+L+ Sbjct 794 LMPYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLV------ 847 Query 749 EGTSPFIKLSDPGVG--LGALSREERVER----IPWLAPECLPGGANSLSTAMDKWGFGA 802 T +K++D G+ LGA +E E I W+A E + + D W +G Sbjct 848 -KTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRI--YTHQSDVWSYGV 904 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860 T+ E+ G P S+ ++ RLP+P + + +C + RP FR Sbjct 905 TVWELMTFGSKPYDGIPASDISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFR 964 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 ++ + +++ ++ + Y + + Sbjct 965 ELILEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDM 1009 >sp|Q7XV05|SERK2_ORYSJ LRR receptor kinase SERK2 OS=Oryza sativa subsp. japonica OX=39947 GN=SERK2 PE=1 SV=1 Length=628 Score = 239 bits (609), Expect = 5e-66, Method: Composition-based stats. Identities = 70/325 (22%), Positives = 122/325 (38%), Gaps = 20/325 (6%) Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916 R + +V + LG G FGKV Sbjct 266 WRRRKPEEHFFDVPAEEDPEVHLGQLKRFSLRELQVATDNFSNKNILGRGGFGKVYKGRL 325 Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976 G +VAVK LK + P ++ E++++ H ++++ +G C E+ L Sbjct 326 -----ADGSLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTER--LL 378 Query 977 VMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028 V Y+ GS+ L + A G++YLH IHRD+ A N Sbjct 379 VYPYMANGSVASRLRERQPNDPPLEWQTRTRIALGSARGLSYLHDHCDPKIIHRDVKAAN 438 Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 +LLD D +GDFGLAK + + V + APE L K +DV+ +G Sbjct 439 ILLDEDFEAVVGDFGLAKLMDYKDTH--VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 496 Query 1089 VTLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 + L EL+T + + + L+ +G + ++ L++ + + + Sbjct 497 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSGFVEHEVESLI 556 Query 1146 HLMKNCWETEASFRPTFENLIPILK 1170 + C + RP ++ +L+ Sbjct 557 QVALLCTQGSPMDRPKMSEVVRMLE 581 Score = 196 bits (499), Expect = 1e-51, Method: Composition-based stats. Identities = 69/324 (21%), Positives = 109/324 (34%), Gaps = 67/324 (21%) Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + S V + + LG+G VY+GRL Sbjct 290 QLKRFSLRELQVATDNFSNKNILGRGGFGKVYKGRLADGS-------------------- 329 Query 633 RGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 V +K L L F ++S H +L + G C+ E ++V Y+ Sbjct 330 -----LVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMA 384 Query 692 HGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745 +G + LR R+ P+ W + +A A LSYL + ++H +V NILL Sbjct 385 NGSVASRLRERQPNDPPLEWQTRTRIALGSARGLSYLHDHCDPKIIHRDVKAANILLDED 444 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800 A + D G+ ++ V I +APE L G + S D +G+ Sbjct 445 FEAV-------VGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 495 Query 801 GATLLEICFDGEAPLQSR--SPSEKEHFYQRQHRLPEPSCPQLAT--------------- 843 G LLE+ A +R + + + L E L Sbjct 496 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSGFVEHEVESL 555 Query 844 --LTSQCLTYEPTQRPSFRTILRD 865 + C P RP ++R Sbjct 556 IQVALLCTQGSPMDRPKMSEVVRM 579 >sp|Q95UN8|M3KSL_DROME Mitogen-activated protein kinase kinase kinase OS=Drosophila melanogaster OX=7227 GN=slpr PE=1 SV=1 Length=1161 Score = 247 bits (631), Expect = 5e-66, Method: Composition-based stats. Identities = 94/299 (31%), Positives = 126/299 (42%), Gaps = 43/299 (14%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA---DCGPQHRSGW 944 P L +G G F KV YD GE VA+K D + R Sbjct 133 QPHEIEYNELDIKEVIGSGGFCKVHRGYYD------GEEVAIKIAHQTGEDDMQRMRDNV 186 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFA 1004 QE + L HE+I +G C + L LVMEY GSL L I L+ +A Sbjct 187 LQEAKLFWALKHENIAALRGVCLN---TKLCLVMEYARGGSLNRILA-GKIPPDVLVNWA 242 Query 1005 QQICEGMAYLHA---QHYIHRDLAARNVLLDN--------DRLVKIGDFGLAKAVPEGHE 1053 QI GM YLH IHRDL + NVL+ + +KI DFGLA+ + Sbjct 243 IQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREM----- 297 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 Y R W PE + + SDVWS+GV L+EL+T P K + + Sbjct 298 YNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITG-----ETPYKGFDPLS 352 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +A G LP P CP LMK+CW+T+ RP F+ ++ L+++ Sbjct 353 VAYGVAVNT---------LTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESI 402 Score = 214 bits (545), Expect = 2e-55, Method: Composition-based stats. Identities = 69/420 (16%), Positives = 136/420 (32%), Gaps = 61/420 (15%) Query 498 QSLRLRKFPIEQQDGAFVLEGWGRSFPSV---------------RELGAALQGCLLRAGD 542 ++ + PI + G G + ++ E+ L +GD Sbjct 36 HHPQIPEIPIPDLEQVETQVGDGSLWTALYDYDAQGEDELTLRRGEIVVVLSTDSEVSGD 95 Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTN 602 + + + + + + + H ++ E+ +G G Sbjct 96 VGWWTGKIGDKVGVFPKDFVTDEDPLQLNVSSAIGDIQPHEIEYNELDIKEVIGSGGFCK 155 Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD----IALAFYET 658 V+ G E V +K+ + D + + Sbjct 156 VHRGYYDGE--------------------------EVAIKIAHQTGEDDMQRMRDNVLQE 189 Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQL 718 A L + H ++A + GVC+ + +V EY G L+ L G +P + A Q+ Sbjct 190 AKLFWALKHENIAALRGVCL-NTKLCLVMEYARGGSLNRIL---AGKIPPDVLVNWAIQI 245 Query 719 ASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT-SPFIKLSDPGVGLGALS--REER 772 A ++YL N +++H ++ N+L+ +K++D G+ + R Sbjct 246 ARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMSA 305 Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH---FYQR 829 W+ PE + ++ S D W +G L E+ GE P + P + Sbjct 306 AGTYAWMPPEVIS--VSTYSKFSDVWSYGVLLWELI-TGETPYKGFDPLSVAYGVAVNTL 362 Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 +P+ L C +P +RP F+ IL+ L + + Sbjct 363 TLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIACSKFTLTPQESFHYMQECW 422 >sp|A9SY39|M3K1A_PHYPA Mitogen-activated protein kinase kinase kinase 1a OS=Physcomitrium patens OX=3218 GN=MEKK1a PE=2 SV=2 Length=759 Score = 242 bits (617), Expect = 5e-66, Method: Composition-based stats. Identities = 79/275 (29%), Positives = 128/275 (47%), Gaps = 31/275 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA----DCGPQHRSGWKQEIDILR 952 K LG G FG V G AVK + G Q ++EI +L Sbjct 426 WAKGEFLGSGTFGSVYEGVAR-----NGTFFAVKEVNLADEGKLGRQAVKQLEREIALLS 480 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 + H +I++Y G ++ E L + +E + GSL + ++ + Q+ + +QI G+ Sbjct 481 DIQHPNIVQYLG--TERTEDKLYIFLELLNKGSLANLYRKYGLFYEQIKAYTEQILTGLK 538 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 YLH + IHRD+ N+L+D + +VK+ DFG+AK V E + + W APE Sbjct 539 YLHDRKIIHRDIKCANILVDTNGVVKLADFGMAKQV----EKFGFAKSFVGSAHWMAPEV 594 Query 1073 LK-EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + ++ +A+D+WS G T+ E+ T + PP LE I + + RG Sbjct 595 VDPKQQYNFAADIWSLGCTVLEMAT-----EGPPFGELEFIAVFW----------KIGRG 639 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 E PD E+ + C + +AS RPT + L+ Sbjct 640 EAPLIPDDLEDELKDFIAQCLQVDASKRPTCDMLL 674 Score = 193 bits (491), Expect = 8e-50, Method: Composition-based stats. Identities = 63/294 (21%), Positives = 110/294 (37%), Gaps = 42/294 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 R + LG GT +VYEG R +E + DE L + Sbjct 419 KRPPWDTWAKGEFLGSGTFGSVYEGVARNGTFFAVKEVNLADEGKLGRQ---------AV 469 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 K L+ +L+S + H ++ G + + E + G L L R Sbjct 470 KQLE-----------REIALLSDIQHPNIVQYLGTERTEDKLYIFLELLNKGSLAN-LYR 517 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 + G +Q+ + L YL ++ ++H ++ NIL+ T+ +KL+D G Sbjct 518 KYGLF-YEQIKAYTEQILTGLKYLHDRKIIHRDIKCANILVD-------TNGVVKLADFG 569 Query 762 VGLGALS---REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + + V W+APE + + A D W G T+LE+ +G P Sbjct 570 MAKQVEKFGFAKSFVGSAHWMAPEVV-DPKQQYNFAADIWSLGCTVLEMATEG-PPFGEL 627 Query 819 SPSEKEHFYQRQHR-----LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 E + + R +P+ +L +QCL + ++RP+ +L Sbjct 628 ---EFIAVFWKIGRGEAPLIPDDLEDELKDFIAQCLQVDASKRPTCDMLLAHPF 678 >sp|P10533|RMIL_AVII1 Serine/threonine-protein kinase-transforming protein Rmil OS=Avian retrovirus IC10 OX=11874 GN=V-RMIL PE=3 SV=1 Length=367 Score = 231 bits (588), Expect = 6e-66, Method: Composition-based stats. Identities = 76/306 (25%), Positives = 130/306 (42%), Gaps = 31/306 (10%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 + + +SD + + +G G FG V + VAVK L Sbjct 45 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-------DVAVKMLNV 97 Query 935 DC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991 PQ +K E+ +LR H +I+ + G + L +V ++ SL +L Sbjct 98 TAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY---STKPQLAIVTQWCEGSSLYHHLHII 154 Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 + +L+ A+Q +GM YLHA+ IHRDL + N+ L D VKIGDFGLA Sbjct 155 ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRW 214 Query 1052 HEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQ--SPPT 1106 ++ E + W APE ++ + + + SDV++FG+ LYEL+T + Sbjct 215 SGSHQF-EQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRD 273 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + + ++G + ++ CP + LM C + + RP F ++ Sbjct 274 QIIFMVGRGYLSPDLSKVR------------SNCPKAMKRLMAECLKKKRDERPLFPQIL 321 Query 1167 PILKTV 1172 ++ + Sbjct 322 ASIELL 327 Score = 222 bits (565), Expect = 7e-63, Method: Composition-based stats. Identities = 67/327 (20%), Positives = 120/327 (37%), Gaps = 53/327 (16%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSF-HRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 P P R +TL S + +IT +G G+ VY+G+ + Sbjct 30 PGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD 89 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSHTH 669 V +K+L+ + AF ++ + H + Sbjct 90 ---------------------------VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVN 122 Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729 + G + P+ +VT++ E L L M + +A+Q A + YL K+ Sbjct 123 ILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKS 181 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPEC 783 ++H ++ NI L +K+ D G+ G+ E+ I W+APE Sbjct 182 IIHRDLKSNNIFLHE-------DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEV 234 Query 784 LPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP------ 836 + N S D + FG L E+ G+ P + + ++ F + L Sbjct 235 IRMQDKNPYSFQSDVYAFGIVLYELM-TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRS 293 Query 837 SCPQ-LATLTSQCLTYEPTQRPSFRTI 862 +CP+ + L ++CL + +RP F I Sbjct 294 NCPKAMKRLMAECLKKKRDERPLFPQI 320 >sp|Q93ZS4|NIK3_ARATH Protein NSP-INTERACTING KINASE 3 OS=Arabidopsis thaliana OX=3702 GN=NIK3 PE=1 SV=1 Length=632 Score = 239 bits (609), Expect = 6e-66, Method: Composition-based stats. Identities = 71/324 (22%), Positives = 127/324 (39%), Gaps = 19/324 (6%) Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916 +R + + +V + + LG G +G V Sbjct 261 WRYRRNKQIFFDVNEQYDPEVSLGHLKRYTFKELRSATNHFNSKNILGRGGYGIVYKG-- 318 Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976 + G +VAVK LK ++ E++ + H ++++ +G C E+ L Sbjct 319 ---HLNDGTLVAVKRLKDCNIAGGEVQFQTEVETISLALHRNLLRLRGFCSSNQER--IL 373 Query 977 VMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028 V Y+P GS+ L + ++ ++ A G+ YLH Q IHRD+ A N Sbjct 374 VYPYMPNGSVASRLKDNIRGEPALDWSRRKKIAVGTARGLVYLHEQCDPKIIHRDVKAAN 433 Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 +LLD D +GDFGLAK + + V V APE L + +DV+ FG Sbjct 434 ILLDEDFEAVVGDFGLAKLLDHRDSH--VTTAVRGTVGHIAPEYLSTGQSSEKTDVFGFG 491 Query 1089 VTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 + L EL+T + + + ++ + +L +L+++ E+ Sbjct 492 ILLLELITGQKALDFGRSAHQKGVMLDWVKKLHQEGKLKQLIDKDLNDKFDRVELEEIVQ 551 Query 1147 LMKNCWETEASFRPTFENLIPILK 1170 + C + S RP ++ +L+ Sbjct 552 VALLCTQFNPSHRPKMSEVMKMLE 575 Score = 193 bits (491), Expect = 1e-50, Method: Composition-based stats. Identities = 62/323 (19%), Positives = 108/323 (33%), Gaps = 66/323 (20%) Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 +L + +F + + LG+G VY+G L Sbjct 285 HLKRYTFKELRSATNHFNSKNILGRGGYGIVYKGHLNDG--------------------- 323 Query 633 RGQELRVVLKVLDPSH-HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 V +K L + + F +S H +L + G C E I+V Y+ Sbjct 324 ----TLVAVKRLKDCNIAGGEVQFQTEVETISLALHRNLLRLRGFCSSNQERILVYPYMP 379 Query 692 HGPLDVWLRRE---RGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745 +G + L+ + + + +A A L YL + ++H +V NILL Sbjct 380 NGSVASRLKDNIRGEPALDWSRRKKIAVGTARGLVYLHEQCDPKIIHRDVKAANILLDED 439 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800 A + D G+ R+ V + +APE L G + S D +GF Sbjct 440 FEAV-------VGDFGLAKLLDHRDSHVTTAVRGTVGHIAPEYLSTGQS--SEKTDVFGF 490 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP------------------SCPQLA 842 G LLE+ +A RS +K +L + ++ Sbjct 491 GILLLELITGQKALDFGRSAHQKGVMLDWVKKLHQEGKLKQLIDKDLNDKFDRVELEEIV 550 Query 843 TLTSQCLTYEPTQRPSFRTILRD 865 + C + P+ RP +++ Sbjct 551 QVALLCTQFNPSHRPKMSEVMKM 573 >sp|Q9LXA5|LRK91_ARATH L-type lectin-domain containing receptor kinase IX.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK91 PE=1 SV=1 Length=651 Score = 239 bits (610), Expect = 6e-66, Method: Composition-based stats. Identities = 69/285 (24%), Positives = 123/285 (43%), Gaps = 18/285 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R LGEG FG V + + MVA+K A Q + + E+ I+ +L Sbjct 333 NNFADDRKLGEGGFGAVYRGYLNSLD----MMVAIKKF-AGGSKQGKREFVTEVKIISSL 387 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMA 1012 H ++++ G C ++ E ++ E++P GSL +L + + + + Sbjct 388 RHRNLVQLIGWCHEKDE--FLMIYEFMPNGSLDAHLFGKKPHLAWHVRCKITLGLASALL 445 Query 1013 YLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH Q +HRD+ A NV+LD++ K+GDFGLA+ + HE + A Sbjct 446 YLHEEWEQCVVHRDIKASNVMLDSNFNAKLGDFGLARLM--DHELGPQTTGLAGTFGYMA 503 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL---RLTE 1126 PE + + SDV+SFGV E++T S + + + + + + Sbjct 504 PEYISTGRASKESDVYSFGVVTLEIVTGRKSVDRRQGRVEPVTNLVEKMWDLYGKGEVIT 563 Query 1127 LLERGERLPRPDKCPCEVYHLM-KNCWETEASFRPTFENLIPILK 1170 ++ R+ D+ E ++ C + + RP+ + I +L Sbjct 564 AIDEKLRIGGFDEKQAECLMIVGLWCAHPDVNTRPSIKQAIQVLN 608 Score = 226 bits (576), Expect = 2e-61, Method: Composition-based stats. Identities = 59/285 (21%), Positives = 97/285 (34%), Gaps = 47/285 (16%) Query 540 AGDDCFSLRRCCLPQPGETSNLIIMRGA---RASPRTLNLSQLSFHRVDQKEITQLSHLG 596 F R+ + ET NL + A PR L+ LG Sbjct 286 TSLIVFLKRKQQKKKAEETENLTSINEDLERGAGPRKFTYKDLAS---AANNFADDRKLG 342 Query 597 QGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFY 656 +G VY G L ++ V +K F Sbjct 343 EGGFGAVYRGYLNSL------------------------DMMVAIKKFAGGSKQGKREFV 378 Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 ++S + H +L + G C E +M+ E++ +G LD L ++ H+ + + Sbjct 379 TEVKIISSLRHRNLVQLIGWCHEKDEFLMIYEFMPNGSLDAHLFGKKPHLAWHVRCKITL 438 Query 717 QLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-----GALS 768 LASAL YL + +VH ++ N++L ++ KL D G+ Sbjct 439 GLASALLYLHEEWEQCVVHRDIKASNVMLD-------SNFNAKLGDFGLARLMDHELGPQ 491 Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 ++APE + G S D + FG LEI ++ Sbjct 492 TTGLAGTFGYMAPEYISTGRA--SKESDVYSFGVVTLEIVTGRKS 534 >sp|Q9LUT0|CARK1_ARATH Receptor-like cytoplasmic kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CARK1 PE=1 SV=1 Length=364 Score = 230 bits (587), Expect = 6e-66, Method: Composition-based stats. Identities = 73/284 (26%), Positives = 120/284 (42%), Gaps = 24/284 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG +G+V +G+ A+K L D Q + ++ ++ L E+++ Sbjct 75 IGEGSYGRVFYGILK-----SGKAAAIKKL--DSSKQPDQEFLAQVSMVSRLRQENVVAL 127 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------IGLAQLLLFAQQICEGMA 1012 G C D + L EY P GSL D L + Q + A G+ Sbjct 128 LGYCVDGPLR--VLAYEYAPNGSLHDILHGRKGVKGAQPGPVLSWHQRVKIAVGAARGLE 185 Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH + H IHRD+ + NVLL +D + KI DF L+ P+ ++A Sbjct 186 YLHEKANPHVIHRDIKSSNVLLFDDDVAKIADFDLSNQAPD-MAARLHSTRVLGTFGYHA 244 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE SDV+SFGV L ELLT + P ++ A +++ ++ + + Sbjct 245 PEYAMTGTLSTKSDVYSFGVVLLELLTGRKPVDHTLPRGQQSVVTWATPKLSEDKVKQCV 304 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + P K ++ + C + EA FRP ++ L+ + Sbjct 305 DARLNGEYPPKAVAKLAAVAALCVQYEADFRPNMSIVVKALQPL 348 Score = 202 bits (515), Expect = 3e-56, Method: Composition-based stats. Identities = 74/388 (19%), Positives = 130/388 (34%), Gaps = 85/388 (22%) Query 547 LRRCCLPQPGETSNLIIMRGA---RASPRT----LNLSQLSFHRVDQKEITQL------- 592 RR P N G RA P + + +S + E+ + Sbjct 13 FRRVSETGPKPVHNTGGYNGGHHQRADPPKNLPVIQMQPISVAAIPADELRDITDNYGSK 72 Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 S +G+G+ V+ G L+ +K LD S Sbjct 73 SLIGEGSYGRVFYGILKSGK-------------------------AAAIKKLD-SSKQPD 106 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-------- 704 F S++S++ ++ + G CV GP ++ EY +G L L +G Sbjct 107 QEFLAQVSMVSRLRQENVVALLGYCVDGPLRVLAYEYAPNGSLHDILHGRKGVKGAQPGP 166 Query 705 HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 + ++ +A A L YL K +++H ++ N+LL K++D Sbjct 167 VLSWHQRVKIAVGAARGLEYLHEKANPHVIHRDIKSSNVLL-------FDDDVAKIADFD 219 Query 762 VG------LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 + L + + APE G +LST D + FG LLE+ G P+ Sbjct 220 LSNQAPDMAARLHSTRVLGTFGYHAPEYAMTG--TLSTKSDVYSFGVVLLELL-TGRKPV 276 Query 816 QSRSPSEKEHFYQR------------------QHRLPEPSCPQLATLTSQCLTYEPTQRP 857 P ++ P + +LA + + C+ YE RP Sbjct 277 DHTLPRGQQSVVTWATPKLSEDKVKQCVDARLNGEYPPKAVAKLAAVAALCVQYEADFRP 336 Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSP 885 + +++ L L + T + + Sbjct 337 NMSIVVKALQPLLNPPRSAPQTPHRNPY 364 >sp|Q6ZCZ2|BRL3_ORYSJ Brassinosteroid LRR receptor kinase BRL3 OS=Oryza sativa subsp. japonica OX=39947 GN=BRL3 PE=2 SV=1 Length=1214 Score = 247 bits (631), Expect = 6e-66, Method: Composition-based stats. Identities = 80/367 (22%), Positives = 141/367 (38%), Gaps = 25/367 (7%) Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 ++L + + + + C P S + L + + + + Sbjct 848 HYKLWKFHKNKTKEIQAGCSESLPGSSKSSWKLSGIGEPLSINMAIFENPLRKLTFSDLH 907 Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + + + +G G FG+V G +VAVK L G R + E++ Sbjct 908 QATNGFCAETL--IGSGGFGEVYKAKLK-----DGNIVAVKKLMHFTGQGDRE-FTAEME 959 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFA 1004 + + H +++ G C+ E+ LV EY+ GSL L + A A Sbjct 960 TIGKIKHRNLVPLLGYCKIGDER--LLVYEYMKNGSLDFVLHDKGEANMDLNWATRKKIA 1017 Query 1005 QQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 G+A+LH H IHRD+ + NVLLD + + DFG+A+ + + V Sbjct 1018 IGSARGLAFLHHSCVPHIIHRDMKSSNVLLDGNFDAYVSDFGMARLMNALDSHLTVSMLS 1077 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 +P + PE ++++ DV+S+GV L ELLT L+G + QM Sbjct 1078 GTP-GYVPPEYCQDFRCTTKGDVYSYGVVLLELLTGKKPIDPTEFGDSNLVGWVK-QMVE 1135 Query 1122 LRLTELLERGERLPRPDKCPCEVYH---LMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 R +E+ + + E+Y + C + + + RPT ++ + K Sbjct 1136 DRCSEIYDPTLMATTSSE--LELYQYLKIACRCLDDQPNRRPTMIQVMTMFKEFQVDSGS 1193 Query 1179 QAPSVFS 1185 FS Sbjct 1194 NFLDDFS 1200 Score = 206 bits (525), Expect = 7e-53, Method: Composition-based stats. Identities = 67/376 (18%), Positives = 127/376 (34%), Gaps = 79/376 (21%) Query 527 RELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ 586 +E+ A L + + L P + N+ I R L S L Sbjct 860 KEIQAGCSESLPGSSKSSWKLSGIGEPL---SINMAIFENPL---RKLTFSDLHQ---AT 910 Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + +G G VY+ +L+ V +K L Sbjct 911 NGFCAETLIGSGGFGEVYKAKLKDGNI-------------------------VAVKKLMH 945 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGH 705 F + ++ H +L + G C G E ++V EY+++G LD L + + Sbjct 946 FTGQGDREFTAEMETIGKIKHRNLVPLLGYCKIGDERLLVYEYMKNGSLDFVLHDKGEAN 1005 Query 706 VPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + + W + +A A L++L + +++H ++ N+LL A +SD Sbjct 1006 MDLNWATRKKIAIGSARGLAFLHHSCVPHIIHRDMKSSNVLLDGNFDAY-------VSDF 1058 Query 761 GVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ L+ ++ PE +T D + +G LLE+ G+ P Sbjct 1059 GMARLMNALDSHLTVSMLSGTPGYVPPEYCQD--FRCTTKGDVYSYGVVLLELL-TGKKP 1115 Query 815 LQSRSPSE--KEHFYQRQHRLPEPSCPQLAT------------------LTSQCLTYEPT 854 P+E + ++ E C ++ + +CL +P Sbjct 1116 ---IDPTEFGDSNLVGWVKQMVEDRCSEIYDPTLMATTSSELELYQYLKIACRCLDDQPN 1172 Query 855 QRPSFRTILRDLTRLQ 870 +RP+ ++ Q Sbjct 1173 RRPTMIQVMTMFKEFQ 1188 >sp|Q60700|M3K12_MOUSE Mitogen-activated protein kinase kinase kinase 12 OS=Mus musculus OX=10090 GN=Map3k12 PE=1 SV=1 Length=888 Score = 244 bits (622), Expect = 7e-66, Method: Composition-based stats. Identities = 81/301 (27%), Positives = 123/301 (41%), Gaps = 35/301 (12%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + + D + ++ +G G G V L + GE VAVK Sbjct 132 WTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFH------GEEVAVK 185 Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 ++ I LR L H +II +KG C ++ME+ G L + L Sbjct 186 KVRDLKETD--------IKHLRKLKHPNIITFKGVCTQA--PCYCILMEFCAQGQLYEVL 235 Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 + + L+ ++ I GM YLH IHRDL + N+L+ D +VKI DFG +K + Sbjct 236 RAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELS 295 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 + + V W APE ++ D+WSFGV L+ELLT P K + Sbjct 296 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG-----EIPYKDV 346 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + I G + LP P CP L++ CW ++ RP+F ++ L Sbjct 347 DSSAIIWGVGSN---------SLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHL 397 Query 1170 K 1170 Sbjct 398 D 398 Score = 203 bits (516), Expect = 2e-52, Method: Composition-based stats. Identities = 94/475 (20%), Positives = 161/475 (34%), Gaps = 94/475 (20%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 +A Q V +EI L +G G + V+ G Sbjct 136 GKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLG-------------------- 175 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 R G+E+ V KV D D + ++ H ++ GVC + P ++ Sbjct 176 ----RFHGEEVAVK-KVRDLKETD--------IKHLRKLKHPNIITFKGVCTQAPCYCIL 222 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 E+ G L LR R P + + + +A ++YL ++H ++ N+L+ Sbjct 223 MEFCAQGQLYEVLRAGRPVTP-SLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLIT--- 278 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +K+SD G + ++ + W+APE + +S +D W FG Sbjct 279 ----YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 332 Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 L E+ GE P + S +P L QC +P RPSFR Sbjct 333 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFR 391 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920 IL L L+ S A +V L+ + Sbjct 392 QILLHLDIASADVLSTPQETYFKSQAEWRE-------------------EVKLHFEKIKS 432 Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 +GT L+ + + R + +DI + E + E++ L Y Sbjct 433 EGTCLH----RLEEELVMRRREELRHALDI------------REHYERKLERANNL---Y 473 Query 981 VPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH-AQHYIHRD-----LAARNV 1029 + L +L L L + ++ C G+ H ++ +H + + RNV Sbjct 474 MELNALMLQLELKERELLRREQALERRCPGLLKSHPSRGLLHGNTMEKLIKKRNV 528 >sp|P53669|LIMK1_RAT LIM domain kinase 1 OS=Rattus norvegicus OX=10116 GN=Limk1 PE=1 SV=1 Length=647 Score = 239 bits (609), Expect = 7e-66, Method: Composition-based stats. Identities = 75/309 (24%), Positives = 132/309 (43%), Gaps = 33/309 (11%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 +F L LG+G FG+ T+ TGE++ +K L + + + Sbjct 328 CRPHRIFRPSDLIHGEVLGKGCFGQ----AIKVTHRETGEVMVMKEL-IRFDEETQRTFL 382 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLF 1003 +E+ ++R L H +++K+ G +K L + EY+ G+LR + +Q + F Sbjct 383 KEVKVMRCLEHPNVLKFIGVLYK--DKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSF 440 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY-------- 1055 A+ I GMAYLH+ + IHRDL + N L+ +R V + DFGLA+ + + Sbjct 441 AKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLARLMIDEKGQSEDLRSLKK 500 Query 1056 ---RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 + R +W APE + + DV+SFG+ L E++ ++ + ++ Sbjct 501 PDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFG 560 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +G + P CP + + C + + RP+F L L+T+ Sbjct 561 LNVRGFLDRY-------------CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETL 607 Query 1173 HEKYQGQAP 1181 G P Sbjct 608 RMHLAGHLP 616 Score = 208 bits (529), Expect = 2e-55, Method: Composition-based stats. Identities = 59/308 (19%), Positives = 111/308 (36%), Gaps = 54/308 (18%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ LG+G + R G +V+K L Sbjct 336 PSDLIHGEVLGKGCFGQAIKVTHRETGE------------------------VMVMKELI 371 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + F + +M + H ++ GV + +TEY++ G L ++ Sbjct 372 RFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQ 431 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL- 764 P + ++ A+ +AS ++YL + N++H ++ N L+ + + ++D G+ Sbjct 432 YPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRE-------NRNVVVADFGLARL 484 Query 765 -----------------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 R V W+APE + G S +D + FG L EI Sbjct 485 MIDEKGQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMING--RSYDEKVDVFSFGIVLCEI 542 Query 808 C--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILR 864 + + R+ + R P+CP +T +C +P +RPSF + + Sbjct 543 IGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQ 602 Query 865 DLTRLQPH 872 L L+ H Sbjct 603 WLETLRMH 610 >sp|Q64716|INSRR_RAT Insulin receptor-related protein OS=Rattus norvegicus OX=10116 GN=Insrr PE=1 SV=3 Length=1300 Score = 248 bits (632), Expect = 7e-66, Method: Composition-based stats. Identities = 95/329 (29%), Positives = 154/329 (47%), Gaps = 36/329 (11%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT-GEMVAV 929 ++ D + + IR+LG+G FG V G VA+ Sbjct 953 YTSVNPEYFSASHMYVPDEWEVPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVAL 1012 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K + + R + +E +++ H+++ G QG+ +L ++ME + G L+ + Sbjct 1013 KTVNELASARERVEFLKEASVMKAFKCHHVVRLLGVV-SQGQPTL-VIMELMTRGDLKSH 1070 Query 990 LP------RHSIGLAQ-----LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 L ++ GL Q ++ A +I +GMAYL A+ ++HRDLAARN ++ D VK Sbjct 1071 LRSLRPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQDFTVK 1130 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 IGDFG+ + V E +YYR G PV W APE LK+ F SDVWSFGV L+E++T Sbjct 1131 IGDFGMTRDVYE-TDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVT-- 1187 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 L ++ ++ + + G L + CP ++ LM+ CW+ Sbjct 1188 ------------LAEQPYQGLSNEQVLKFVMDGGVLEEQEDCPIQLQELMRRCWQHTPRL 1235 Query 1159 RPTFENLIPILKTVHEKYQGQAPSVFSVC 1187 RPTF + IL + ++ + F +C Sbjct 1236 RPTF---VHILDRIQDELRPS----FRLC 1257 Score = 241 bits (614), Expect = 1e-63, Method: Composition-based stats. Identities = 74/324 (23%), Positives = 123/324 (38%), Gaps = 46/324 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 V +++I + LGQG+ VYEG R +G+ + V L Sbjct 972 WEVPREQIAIIRELGQGSFGMVYEGLARGLEAGE-------------------ESTPVAL 1012 Query 642 KVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K ++ + + F + AS+M H+ + GV +G +++ E + G L LR Sbjct 1013 KTVNELASARERVEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLR 1072 Query 701 RERGHVP---------MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 R ++ + +A ++A ++YL K VH ++ RN ++++ Sbjct 1073 SLRPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQ------- 1125 Query 752 SPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLL 805 +K+ D G+ + + + W+APE L G +T D W FG L Sbjct 1126 DFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGI--FTTHSDVWSFGVVLW 1183 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTIL 863 EI E P Q S + F L E CP QL L +C + P RP+F IL Sbjct 1184 EIVTLAEQPYQGLSNEQVLKFVMDGGVLEEQEDCPIQLQELMRRCWQHTPRLRPTFVHIL 1243 Query 864 RDLTRLQPHNLADVLTVNPDSPAS 887 + + Sbjct 1244 DRIQDELRPSFRLCSFYYSPECQR 1267 >sp|Q8BKG3|PTK7_MOUSE Inactive tyrosine-protein kinase 7 OS=Mus musculus OX=10090 GN=Ptk7 PE=1 SV=1 Length=1062 Score = 246 bits (628), Expect = 7e-66, Method: Composition-based stats. Identities = 91/335 (27%), Positives = 144/335 (43%), Gaps = 30/335 (9%) Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 +CL P Q +++ L T S L+ I LG+ Sbjct 738 MECLNGGPLQNGQPSAEIQEEVALTSLGSGPPATNKRHSAGDRMHFPRAS-LQPITTLGK 796 Query 906 GHFGKVSLYCYDPTNDG-TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG 964 FG+V L +G T +V VK+L Q + +++E+++ L H ++++ G Sbjct 797 SEFGEVFLAKAQGVEEGATETLVLVKSL-QSRDEQQQLDFRREVEMFGKLNHANVVRLLG 855 Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQLLLFAQQICEGMAYL 1014 C + +V+EYV LG L+ +L + Q + Q+ GM +L Sbjct 856 LCREAEPH--YMVLEYVDLGDLKQFLRISKNKDEKLKSQPLSTKQKVALCSQVALGMEHL 913 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 ++H+DLAARN L+ R VK+ GL+K V Y+ P+ W +PE + Sbjct 914 SNNRFVHKDLAARNCLISAQRQVKVSALGLSKDVYNSEYYHF--RQAWVPLRWMSPEAVL 971 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 E F SDVW+FGV ++E+ TH + GQ L +L RL Sbjct 972 EGDFSTKSDVWAFGVLMWEVFTHGEMPHG-------------GQADDEVLADLQAGKARL 1018 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P+P+ CP ++Y LM+ CW RP+F + L Sbjct 1019 PQPEGCPSKLYRLMQRCWAPNPKDRPSFSEIASTL 1053 Score = 223 bits (569), Expect = 2e-58, Method: Composition-based stats. Identities = 77/338 (23%), Positives = 130/338 (38%), Gaps = 47/338 (14%) Query 544 CFSLRRCCLPQPG-ETSNLIIMRGARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTR 600 C + QP E + + + P N + R+ + + ++ LG+ Sbjct 740 CLNGGPLQNGQPSAEIQEEVALTSLGSGPPATNKRHSAGDRMHFPRASLQPITTLGKSEF 799 Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660 V+ + + G E V++K L L F Sbjct 800 GEVFLAKAQGVEEG-------------------ATETLVLVKSLQSRDEQQQLDFRREVE 840 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH------VPMAWKMVV 714 + +++H ++ + G+C + MV EYV+ G L +LR + P++ K V Sbjct 841 MFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKNKDEKLKSQPLSTKQKV 900 Query 715 AQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 A Q+A + +L N VH ++ RN L++ +K+S G+ + E Sbjct 901 ALCSQVALGMEHLSNNRFVHKDLAARNCLIS-------AQRQVKVSALGLSKDVYNSEYY 953 Query 773 VER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HF 826 R + W++PE + G ST D W FG + E+ GE P ++ E Sbjct 954 HFRQAWVPLRWMSPEAVLEG--DFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADL 1011 Query 827 YQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862 + RLP+P CP +L L +C P RPSF I Sbjct 1012 QAGKARLPQPEGCPSKLYRLMQRCWAPNPKDRPSFSEI 1049 >sp|P00532|RAF_MSV36 Serine/threonine-protein kinase-transforming protein raf OS=Murine sarcoma virus 3611 OX=11812 GN=V-RAF PE=3 SV=1 Length=323 Score = 229 bits (583), Expect = 8e-66, Method: Composition-based stats. Identities = 77/303 (25%), Positives = 128/303 (42%), Gaps = 31/303 (10%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCG 937 +S + +G G FG V + VAVK LK D Sbjct 6 RPRGQRDSSYYWKMEASEVMLSTRIGSGSFGTVYKGKWHG-------DVAVKILKVVDPT 58 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSI 995 P+ ++ E+ +LR H +I+ + G + +L +V ++ SL +L Sbjct 59 PEQLQAFRNEVAVLRKTRHVNILLFMGYM---TKDNLAIVTQWCEGSSLYKHLHVQETKF 115 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + QL+ A+Q +GM YLHA++ IHRD+ + N+ L VKIGDFGLA Sbjct 116 QMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQ 175 Query 1056 RVREDGDSPVFWYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQS--PPTKFLE 1110 +V E V W APE ++ + F + SDV+S+G+ LYEL+ + + Sbjct 176 QV-EQPTGSVLWMAPEVIRMQDDNPFSFQSDVYSYGIVLYELMAGELPYAHINNRDQIIF 234 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 ++G + RL + CP + L+ +C + RP F ++ ++ Sbjct 235 MVGRGYASPDLSRLYK------------NCPKAIKRLVADCVKKVKEERPLFPQILSSIE 282 Query 1171 TVH 1173 + Sbjct 283 LLQ 285 Score = 216 bits (550), Expect = 2e-61, Method: Composition-based stats. Identities = 69/357 (19%), Positives = 125/357 (35%), Gaps = 62/357 (17%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 N I RG R S + +++ E+ + +G G+ VY+G+ + Sbjct 1 EKNKIRPRGQRDSSY--------YWKMEASEVMLSTRIGSGSFGTVYKGKWHGD------ 46 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQVSHTHLAFVH 674 V +K+L DP+ + AF +++ + H ++ Sbjct 47 ---------------------VAVKILKVVDPTPEQLQ-AFRNEVAVLRKTRHVNILLFM 84 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGN 734 G + +VT++ E L L + M + +A+Q A + YL KN++H + Sbjct 85 GYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRD 143 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGG- 787 + NI L +K+ D G+ G+ E+ + W+APE + Sbjct 144 MKSNNIFLHEGL-------TVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQD 196 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH-------RLPEPSCPQ 840 N S D + +G L E+ GE P + ++ F + RL + Sbjct 197 DNPFSFQSDVYSYGIVLYELMA-GELPYAHINNRDQIIFMVGRGYASPDLSRLYKNCPKA 255 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897 + L + C+ +RP F IL + LQ + S Sbjct 256 IKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSAPEPSLHRAAHTEDINAC 312 >sp|Q23915|KINX_DICDI Probable serine/threonine-protein kinase kinX OS=Dictyostelium discoideum OX=44689 GN=kinX PE=3 SV=2 Length=1094 Score = 246 bits (628), Expect = 8e-66, Method: Composition-based stats. Identities = 75/296 (25%), Positives = 125/296 (42%), Gaps = 32/296 (11%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA---DCGPQHRSGWK- 945 L I ++G G FGKV Y G VA+K + D + Sbjct 15 WSIKYEDLDFISEIGSGGFGKVFKGEYL------GAPVAIKKIHILPDDPNRVDLEKFLN 68 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL--F 1003 +EI+ ++ H ++I++ G E+ G L +V E + G L+ YL SI L L Sbjct 69 REIETIKLFTHPNVIQFVGISENNG--ILFIVTELIEGGDLQYYLKNQSIDLPWFLRANI 126 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 A + M+YLH++ +HRDL + N+L+D + +K+ DFG A+ V E + Sbjct 127 ALDVSLAMSYLHSKSIVHRDLKSTNLLVDKNWKIKVCDFGFARIVEEDNNKSMT---ICG 183 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 W +PE + + SD++SFG+ L E+++ + + Sbjct 184 TDNWMSPEMITGLDYDERSDIFSFGIVLLEIISRVKPA-------------PYMRDASFG 230 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L E + R + P CP + L NC + + RP+F+ + LK + Sbjct 231 LAEDIVRNQL--IPTDCPESLIDLTFNCCSVDPNNRPSFKEISQTLKQIKTTLDSN 284 Score = 216 bits (551), Expect = 3e-56, Method: Composition-based stats. Identities = 64/331 (19%), Positives = 122/331 (37%), Gaps = 45/331 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + +++ +S +G G V++G E G P V + Sbjct 15 WSIKYEDLDFISEIGSGGFGKVFKG----EYLGAP----------------------VAI 48 Query 642 KVL-----DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 K + DP+ D+ + +H ++ G+ +VTE +E G L Sbjct 49 KKIHILPDDPNRVDLEKFLNREIETIKLFTHPNVIQFVGISENNGILFIVTELIEGGDLQ 108 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 +L+ + +P + +A ++ A+SYL +K++VH ++ N+L+ + + IK Sbjct 109 YYLKNQSIDLPWFLRANIALDVSLAMSYLHSKSIVHRDLKSTNLLVDK-------NWKIK 161 Query 757 LSDPGVGLGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 + D G + I W++PE + G D + FG LLEI + Sbjct 162 VCDFGFARIVEEDNNKSMTICGTDNWMSPEMITG--LDYDERSDIFSFGIVLLEIISRVK 219 Query 813 A-PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P + R +P L LT C + +P RPSF+ I + L +++ Sbjct 220 PAPYMRDASFGLAEDIVRNQLIPTDCPESLIDLTFNCCSVDPNNRPSFKEISQTLKQIKT 279 Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902 ++++ + K Sbjct 280 TLDSNIVYPEIRDFEQQQKISTTNGNNKQNG 310 >sp|P09208|INSR_DROME Insulin-like receptor OS=Drosophila melanogaster OX=7227 GN=InR PE=1 SV=3 Length=2144 Score = 249 bits (635), Expect = 8e-66, Method: Composition-based stats. Identities = 88/324 (27%), Positives = 147/324 (45%), Gaps = 41/324 (13%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN-DGTGEMVAV 929 N D + + ++ LG+G FG V +G A+ Sbjct 1345 HMNTEVNPFYASMQYIPDDWEVLRENIIQLAPLGQGSFGMVYEGILKSFPPNGVDRECAI 1404 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K + + + R+ + E +++ H+++ G C +G+ +L +VME + G L+ Y Sbjct 1405 KTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVC-SRGQPAL-VVMELMKKGDLKSY 1462 Query 990 LPRHSIGL-----------------------AQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 L H ++ A +I +GMAYL A+ ++HRDLAA Sbjct 1463 LRAHRPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAA 1522 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RN ++ +D VKIGDFG+ + + E +YYR G PV W PE L++ + ASDV+S Sbjct 1523 RNCMVADDLTVKIGDFGMTRDIYE-TDYYRKGTKGLLPVRWMPPESLRDGVYSSASDVFS 1581 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 FGV L+E+ T L ++ ++ + G + RP+ CP ++ Sbjct 1582 FGVVLWEMAT--------------LAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHK 1627 Query 1147 LMKNCWETEASFRPTFENLIPILK 1170 LM+ CW +S RP+F ++I L+ Sbjct 1628 LMQRCWHHRSSARPSFLDIIAYLE 1651 Score = 232 bits (592), Expect = 1e-60, Method: Composition-based stats. Identities = 76/362 (21%), Positives = 123/362 (34%), Gaps = 63/362 (17%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 V ++ I QL+ LGQG+ VYEG L+ G + Sbjct 1362 DDWEVLRENIIQLAPLGQGSFGMVYEGILKSFPP-------------------NGVDREC 1402 Query 640 VLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +K ++ + D F AS+M + H+ + GVC RG ++V E ++ G L + Sbjct 1403 AIKTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSY 1462 Query 699 LRRERG---------------------HVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737 LR R +A ++A ++YL K VH ++ Sbjct 1463 LRAHRPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAA 1522 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSL 791 RN ++A +K+ D G+ + + + W+ PE L G Sbjct 1523 RNCMVA-------DDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGV--Y 1573 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCL 849 S+A D + FG L E+ P Q S + + + PE L L +C Sbjct 1574 SSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCW 1633 Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 + + RPSF I+ L S R ++ F Sbjct 1634 HHRSSARPSFLDIIAYLE-----PQCPNSQFKEVSFYHSEAGLQHREKERKERNQLDAFA 1688 Query 910 KV 911 V Sbjct 1689 AV 1690 >sp|Q12852|M3K12_HUMAN Mitogen-activated protein kinase kinase kinase 12 OS=Homo sapiens OX=9606 GN=MAP3K12 PE=1 SV=2 Length=859 Score = 243 bits (620), Expect = 9e-66, Method: Composition-based stats. Identities = 81/301 (27%), Positives = 123/301 (41%), Gaps = 35/301 (12%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + + D + ++ +G G G V L + GE VAVK Sbjct 99 WTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFH------GEEVAVK 152 Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 ++ I LR L H +II +KG C ++ME+ G L + L Sbjct 153 KVRDLKETD--------IKHLRKLKHPNIITFKGVCTQA--PCYCILMEFCAQGQLYEVL 202 Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 + + L+ ++ I GM YLH IHRDL + N+L+ D +VKI DFG +K + Sbjct 203 RAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELS 262 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 + + V W APE ++ D+WSFGV L+ELLT P K + Sbjct 263 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG-----EIPYKDV 313 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + I G + LP P CP L++ CW ++ RP+F ++ L Sbjct 314 DSSAIIWGVGSN---------SLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHL 364 Query 1170 K 1170 Sbjct 365 D 365 Score = 201 bits (512), Expect = 4e-52, Method: Composition-based stats. Identities = 67/305 (22%), Positives = 109/305 (36%), Gaps = 50/305 (16%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 +A Q V +EI L +G G + V+ G Sbjct 103 GKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLG-------------------- 142 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 R G+E+ V KV D D + ++ H ++ GVC + P ++ Sbjct 143 ----RFHGEEVAVK-KVRDLKETD--------IKHLRKLKHPNIITFKGVCTQAPCYCIL 189 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 E+ G L LR R P + + + +A ++YL ++H ++ N+L+ Sbjct 190 MEFCAQGQLYEVLRAGRPVTP-SLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLIT--- 245 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +K+SD G + ++ + W+APE + +S +D W FG Sbjct 246 ----YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 299 Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 L E+ GE P + S +P L QC +P RPSFR Sbjct 300 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFR 358 Query 861 TILRD 865 IL Sbjct 359 QILLH 363 >sp|P06494|ERBB2_RAT Receptor tyrosine-protein kinase erbB-2 OS=Rattus norvegicus OX=10116 GN=Erbb2 PE=1 SV=3 Length=1257 Score = 247 bits (631), Expect = 9e-66, Method: Composition-based stats. Identities = 87/272 (32%), Positives = 133/272 (49%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + VA+K L+ + P+ E ++ + ++ + Sbjct 728 LGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRL 787 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C +QLV + +P G L D++ H +G LL + QI +GM+YL + Sbjct 788 LGICLTST---VQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLV 844 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W A E + +F + Sbjct 845 HRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWMALESILRRRFTH 903 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + + +LLE+GERLP+P C Sbjct 904 QSDVWSYGVTVWELMTFG--------------AKPYDGIPAREIPDLLEKGERLPQPPIC 949 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW ++ RP F L+ + Sbjct 950 TIDVYMIMVKCWMIDSECRPRFRELVSEFSRM 981 Score = 219 bits (559), Expect = 5e-57, Method: Composition-based stats. Identities = 68/335 (20%), Positives = 128/335 (38%), Gaps = 39/335 (12%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P +Q + + E+ ++ LG G VY+G +G Sbjct 703 TPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENV-------------- 748 Query 630 GRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ V +KVL + + A +M+ V +++ + G+C+ +VT+ Sbjct 749 ------KIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQ 801 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + +G L +R RG + + Q+A +SYLE+ LVH ++ RN+L+ Sbjct 802 LMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPN-- 859 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 +K++D G+ + I W+A E + + D W +G Sbjct 860 -----HVKITDFGLARLLDIDETEYHADGGKVPIKWMALESIL--RRRFTHQSDVWSYGV 912 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860 T+ E+ G P E ++ RLP+P + + +C + RP FR Sbjct 913 TVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFR 972 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895 ++ + +R+ V+ N D S P Sbjct 973 ELVSEFSRMARDPQRFVVIQNEDLGPSSPMDSTFY 1007 >sp|Q9ES74|NEK7_MOUSE Serine/threonine-protein kinase Nek7 OS=Mus musculus OX=10090 GN=Nek7 PE=1 SV=1 Length=302 Score = 228 bits (580), Expect = 9e-66, Method: Composition-based stats. Identities = 65/311 (21%), Positives = 119/311 (38%), Gaps = 30/311 (10%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + D + + +G G F +V Y + G VA+K Sbjct 8 MQGPPVTQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEV----YRASCLLDGVPVALK 63 Query 931 ALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 ++ + R+ +EID+L+ L H ++IKY + E L +V+E G L Sbjct 64 KVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNE--LNIVLELADAGDLSR 121 Query 989 YLPRHS-----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 + I + + Q+C + ++H++ +HRD+ NV + +VK+GD G Sbjct 122 MIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLG 181 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 L + ++ +PE + E + + SD+WS G LYE+ Sbjct 182 LGRFFS---SKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYG 238 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRP-DKCPCEVYHLMKNCWETEASFRPTF 1162 +M + L + +E+ + P P D E+ L+ C + RP Sbjct 239 -------------DKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDI 285 Query 1163 ENLIPILKTVH 1173 + + K +H Sbjct 286 AYVYDVAKRMH 296 Score = 171 bits (434), Expect = 4e-46, Method: Composition-based stats. Identities = 48/299 (16%), Positives = 100/299 (33%), Gaps = 47/299 (16%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL--- 644 +G+G + VY ++G + V LK + Sbjct 33 NFRIEKKIGRGQFSEVYRASCLLDG------------------------VPVALKKVQIF 68 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD---VWLRR 701 D + L+ Q++H ++ + + E +V E + G L ++ Sbjct 69 DLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKK 128 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 ++ +P QL SAL ++ ++ ++H ++ N+ + G+ +KL D G Sbjct 129 QKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGV-------VKLGDLG 181 Query 762 VGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 +G S+ V +++PE + + D W G L E+ Sbjct 182 LGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNF--KSDIWSLGCLLYEMAALQSPFYGD 239 Query 818 RSPS----EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 + +K + +L L + C+ +P +RP + R+ Sbjct 240 KMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHAC 298 >sp|Q9LFH9|LRK81_ARATH L-type lectin-domain containing receptor kinase VIII.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK81 PE=2 SV=1 Length=715 Score = 240 bits (612), Expect = 9e-66, Method: Composition-based stats. Identities = 64/279 (23%), Positives = 119/279 (43%), Gaps = 21/279 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V Y TG++VAVK + ++ + E+ I+ +L H ++++ Sbjct 382 IGHGAFGVV----YRGILPETGDIVAVKRCSHSSQDK-KNEFLSELSIIGSLRHRNLVRL 436 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLH---AQ 1017 +G C ++GE + LV + +P GSL L R ++ + +AYLH Sbjct 437 QGWCHEKGE--ILLVYDLMPNGSLDKALFESRFTLPWDHRKKILLGVASALAYLHRECEN 494 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ + N++LD K+GDFGLA+ + + + APE L + Sbjct 495 QVIHRDVKSSNIMLDESFNAKLGDFGLARQIEHDKSPEAT--VAAGTMGYLAPEYLLTGR 552 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFL-------ELIGIAQGQMTVLRLTELLER 1130 +DV+S+G + E+++ + L+ G +++ + Sbjct 553 ASEKTDVFSYGAVVLEVVSGRRPIEKDLNVQRHNVGVNPNLVEWVWGLYKEGKVSAAADS 612 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + V + C + +FRPT +++ +L Sbjct 613 RLEGKFDEGEMWRVLVVGLACSHPDPAFRPTMRSVVQML 651 Score = 218 bits (556), Expect = 2e-58, Method: Composition-based stats. Identities = 58/265 (22%), Positives = 98/265 (37%), Gaps = 45/265 (17%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P+ + +L + K + +G G VY G L G Sbjct 360 APKEFSYKEL---KAGTKNFNESRIIGHGAFGVVYRGILPETGD---------------- 400 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 V +K S D F S++ + H +L + G C E ++V + Sbjct 401 --------IVAVKRCSHSSQDKKNEFLSELSIIGSLRHRNLVRLQGWCHEKGEILLVYDL 452 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLG 746 + +G LD L R +P + + +ASAL+YL ++H +V NI+L Sbjct 453 MPNGSLDKALFESRFTLPWDHRKKILLGVASALAYLHRECENQVIHRDVKSSNIMLDE-- 510 Query 747 LAEGTSPFIKLSDPGVGLGALSREE-----RVERIPWLAPECLPGGANSLSTAMDKWGFG 801 S KL D G+ + + +LAPE L G S D + +G Sbjct 511 -----SFNAKLGDFGLARQIEHDKSPEATVAAGTMGYLAPEYLLTGRA--SEKTDVFSYG 563 Query 802 ATLLEICFDGEAPLQSRSPSEKEHF 826 A +LE+ G P++ ++ + Sbjct 564 AVVLEVVS-GRRPIEKDLNVQRHNV 587 >sp|Q9FJ55|CIPKJ_ARATH CBL-interacting serine/threonine-protein kinase 19 OS=Arabidopsis thaliana OX=3702 GN=CIPK19 PE=1 SV=1 Length=483 Score = 234 bits (596), Expect = 9e-66, Method: Composition-based stats. Identities = 67/269 (25%), Positives = 115/269 (43%), Gaps = 26/269 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960 LG G F KV L N +GE VA+K + + + + K+EI ILR + H +I+ Sbjct 34 LGHGTFAKVYL----ARNAQSGESVAIKVIDKEKVLKSGLIAHIKREISILRRVRHPNIV 89 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + + + + VMEYV G L + + + + + QQ+ +++ H + Sbjct 90 QLFEVMATKSK--IYFVMEYVKGGELFNKVAKGRLKEEMARKYFQQLISAVSFCHFRGVY 147 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 HRDL N+LLD + +K+ DFGL+ + + +P + APE L + Sbjct 148 HRDLKPENLLLDENGNLKVSDFGLSAVSDQIRQDGLFHTFCGTPA-YVAPEVLARKGYDG 206 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 D+WS GV L+ L+ V+ + + + RG+ P Sbjct 207 AKVDIWSCGVILFVLMAGFLPFHD---------------RNVMAMYKKIYRGD-FRCPRW 250 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPI 1168 P E+ L+ ET+ R T +++ Sbjct 251 FPVEINRLLIRMLETKPERRFTMPDIMET 279 Score = 180 bits (457), Expect = 3e-47, Method: Composition-based stats. Identities = 57/310 (18%), Positives = 97/310 (31%), Gaps = 45/310 (15%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + LG GT VY R G V +KV+D Sbjct 27 KYEMGRLLGHGTFAKVYLARNAQSGES------------------------VAIKVIDKE 62 Query 648 H---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + S++ +V H ++ + V + V EYV+ G L + +G Sbjct 63 KVLKSGLIAHIKREISILRRVRHPNIVQLFEVMATKSKIYFVMEYVKGGELFN--KVAKG 120 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763 + QQL SA+S+ + + H ++ N+LL G +K+SD G+ Sbjct 121 RLKEEMARKYFQQLISAVSFCHFRGVYHRDLKPENLLLDENG-------NLKVSDFGLSA 173 Query 764 -----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 ++APE L +D W G L + G P R Sbjct 174 VSDQIRQDGLFHTFCGTPAYVAPEVLARKGYD-GAKVDIWSCGVIL-FVLMAGFLPFHDR 231 Query 819 SPSEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 + R R P ++ L + L +P +R + I+ + Sbjct 232 NVMAMYKKIYRGDFRCPRWFPVEINRLLIRMLETKPERRFTMPDIMETSWFKKGFKHIKF 291 Query 878 LTVNPDSPAS 887 + + Sbjct 292 YVEDDHQLCN 301 >sp|Q9V6K3|ROR2_DROME Tyrosine-protein kinase transmembrane receptor Ror2 OS=Drosophila melanogaster OX=7227 GN=Nrk PE=1 SV=2 Length=724 Score = 240 bits (613), Expect = 1e-65, Method: Composition-based stats. Identities = 86/320 (27%), Positives = 137/320 (43%), Gaps = 32/320 (10%) Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP-T 919 TI + L + + + + + +R LG+G FG+V Sbjct 405 TIHSNCVALTTVTNVSDAKGTKPNARLEKLEYPRGDIVYVRSLGQGAFGRVFQARAPGLV 464 Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979 D +VAVK LK D Q + +++E +L H +I++ G C + + L+ E Sbjct 465 PDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVRLLGVCALG--RPMCLLFE 522 Query 980 YVPLGSLRDYLP--------------RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 Y+ G L ++L R + LL A I GM YL + ++HRDLA Sbjct 523 YMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQMAANIAAGMLYLSERKFVHRDLA 582 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 RN L++ VKI DFGL+ + +YY+ E+ P+ W E + KF SDVW Sbjct 583 TRNCLINEHMAVKIADFGLSHKIYL-QDYYKGDENDFIPIRWMPLESILYNKFSLESDVW 641 Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 ++G+ L+E+ + +T + + ++ G L PD P VY Sbjct 642 AYGICLWEVFSFALQ--------------PYFGLTHEEVIKYIKEGNVLGCPDNTPLSVY 687 Query 1146 HLMKNCWETEASFRPTFENL 1165 LM+ CW + S RP F + Sbjct 688 ALMRRCWNRKPSERPGFAEI 707 Score = 232 bits (592), Expect = 5e-63, Method: Composition-based stats. Identities = 68/332 (20%), Positives = 127/332 (38%), Gaps = 57/332 (17%) Query 559 SNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEE 618 +N+ +G + + R L + +I + LGQG V++ R Sbjct 417 TNVSDAKGTKPNAR------LEKLEYPRGDIVYVRSLGQGAFGRVFQAR----------- 459 Query 619 GKMDDEDPLVPGRDRGQE-LRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676 PG QE L V +K+L D + + + F A L+++ H ++ + GV Sbjct 460 ---------APGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVRLLGV 510 Query 677 CVRGPENIMVTEYVEHGPLDVWLR------------RERGHVPMAWKMVVAQQLASALSY 724 C G ++ EY+ G L +LR ++R + + +A +A+ + Y Sbjct 511 CALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQMAANIAAGMLY 570 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVE------RIPW 778 L + VH ++ RN L+ +K++D G+ ++ I W Sbjct 571 LSERKFVHRDLATRNCLINE-------HMAVKIADFGLSHKIYLQDYYKGDENDFIPIRW 623 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEP 836 + E + N S D W +G L E+ P + E + + + L P+ Sbjct 624 MPLESIL--YNKFSLESDVWAYGICLWEVFSFALQPYFGLTHEEVIKYIKEGNVLGCPDN 681 Query 837 SCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + + L +C +P++RP F I + Sbjct 682 TPLSVYALMRRCWNRKPSERPGFAEINHCIQH 713 >sp|Q60553|ERBB2_MESAU Receptor tyrosine-protein kinase erbB-2 OS=Mesocricetus auratus OX=10036 GN=ERBB2 PE=2 SV=1 Length=1254 Score = 247 bits (631), Expect = 1e-65, Method: Composition-based stats. Identities = 88/272 (32%), Positives = 133/272 (49%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + VA+K L+ + P+ E ++ L ++ + Sbjct 726 LGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGLGSPYVSRL 785 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C +QLV + +P G L D++ H +G LL + QI +GM+YL + Sbjct 786 LGICLTST---VQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLV 842 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W A E + +F + Sbjct 843 HRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWIALESILRRRFTH 901 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + + +LLE+GERLP+P C Sbjct 902 QSDVWSYGVTVWELMTFG--------------AKPYDGIPAREIPDLLEKGERLPQPPIC 947 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW ++ RP F L+ + Sbjct 948 TIDVYMIMVKCWMIDSECRPRFRELVSEFSRM 979 Score = 218 bits (556), Expect = 1e-56, Method: Composition-based stats. Identities = 62/316 (20%), Positives = 122/316 (39%), Gaps = 39/316 (12%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P +Q + + E+ ++ LG G VY+G +G Sbjct 701 TPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENV-------------- 746 Query 630 GRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ V +KVL + + A +M+ + +++ + G+C+ +VT+ Sbjct 747 ------KIPVAIKVLRENTSPKANKEILDEAYVMAGLGSPYVSRLLGICLTSTVQ-LVTQ 799 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + +G L +R RG + + Q+A +SYLE+ LVH ++ RN+L+ Sbjct 800 LMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPN-- 857 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 +K++D G+ + I W+A E + + D W +G Sbjct 858 -----HVKITDFGLARLLDIDETEYHADGGKVPIKWIALESIL--RRRFTHQSDVWSYGV 910 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860 T+ E+ G P E ++ RLP+P + + +C + RP FR Sbjct 911 TVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFR 970 Query 861 TILRDLTRLQPHNLAD 876 ++ + +R+ Sbjct 971 ELVSEFSRMARDPQRF 986 >sp|Q69JN6|BRL1_ORYSJ Brassinosteroid LRR receptor kinase BRL1 OS=Oryza sativa subsp. japonica OX=39947 GN=BRL1 PE=2 SV=1 Length=1214 Score = 247 bits (630), Expect = 1e-65, Method: Composition-based stats. Identities = 71/295 (24%), Positives = 124/295 (42%), Gaps = 22/295 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG+V G +VA+K L G R + E++ + + H +++ Sbjct 918 IGSGGFGEVYKAKLK-----DGSVVAIKKLIHFTGQGDRE-FTAEMETIGKIKHRNLVPL 971 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHAQ 1017 G C+ E+ LV EY+ GSL L + + A G+A+LH Sbjct 972 LGYCKIGDER--LLVYEYMKHGSLDVVLHDKAKASVKLDWSARKKIAIGSARGLAFLHHS 1029 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H IHRD+ + NVLLDN+ ++ DFG+A+ + + V +P + PE + Sbjct 1030 CIPHIIHRDMKSSNVLLDNNLDARVSDFGMARLMNALDTHLSVSTLAGTP-GYVPPEYYQ 1088 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 ++ DV+S+GV L ELL+ L+G + + R +E+ + Sbjct 1089 SFRCTTKGDVYSYGVVLLELLSGKKPIDPTEFGDNNLVGWVKQMVKENRSSEIFDPTLTD 1148 Query 1135 PRPDKCPCEVYH---LMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 + + E+Y + C + + RPT ++ + K + FS+ Sbjct 1149 RKSGEA--ELYQYLKIACECLDDRPNRRPTMIQVMAMFKELQLDSDSDILDGFSI 1201 Score = 211 bits (538), Expect = 2e-54, Method: Composition-based stats. Identities = 60/326 (18%), Positives = 116/326 (36%), Gaps = 65/326 (20%) Query 576 LSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L +L+F + + + +G G VY+ +L+ Sbjct 897 LRKLTFAHLLEATNGFSAETLIGSGGFGEVYKAKLKDGS--------------------- 935 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 V +K L F + ++ H +L + G C G E ++V EY++HG Sbjct 936 ----VVAIKKLIHFTGQGDREFTAEMETIGKIKHRNLVPLLGYCKIGDERLLVYEYMKHG 991 Query 694 PLDVWLRRERG---HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGL 747 LDV L + + + + +A A L++L + +++H ++ N+LL Sbjct 992 SLDVVLHDKAKASVKLDWSARKKIAIGSARGLAFLHHSCIPHIIHRDMKSSNVLLDN--- 1048 Query 748 AEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 + ++SD G+ LS ++ PE + +T D + +G Sbjct 1049 ----NLDARVSDFGMARLMNALDTHLSVSTLAGTPGYVPPEYYQ--SFRCTTKGDVYSYG 1102 Query 802 ATLLEICFDGEA--PLQSRSPSEK--EHFYQRQHRLPEPSCPQLAT-------------L 844 LLE+ + P + + +++R E P L + Sbjct 1103 VVLLELLSGKKPIDPTEFGDNNLVGWVKQMVKENRSSEIFDPTLTDRKSGEAELYQYLKI 1162 Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQ 870 +CL P +RP+ ++ LQ Sbjct 1163 ACECLDDRPNRRPTMIQVMAMFKELQ 1188 >sp|O02466|ILPR_BRALA Insulin-like peptide receptor OS=Branchiostoma lanceolatum OX=7740 PE=2 SV=1 Length=1363 Score = 247 bits (631), Expect = 1e-65, Method: Composition-based stats. Identities = 97/337 (29%), Positives = 150/337 (45%), Gaps = 47/337 (14%) Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923 + + ++ + D D + + IR+LG+G FG V Sbjct 961 QMPNGVLYASVNPEYMSSDDVYVPDEWEVPREKITLIRELGQGSFGMVYEGEAKDVVKDE 1020 Query 924 GEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982 + VAVK + + R + E +++T H++K G +G+ +L +VME + Sbjct 1021 PMVSVAVKTVNESASIRERIEFLNEASVMKTFNCHHVVKLMGVV-SKGQPTL-VVMELMA 1078 Query 983 LGSLRDYLPRHSIGLA-----------------------------QLLLFAQQICEGMAY 1013 LG L++YL RH ++ A I +GM+Y Sbjct 1079 LGDLKNYLRRHRPEEDVGLSDSPASNEAKNSPFAENDNDLPPTFKDIIQMAGVIADGMSY 1138 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 L A+ ++HRDLA RN ++ DR VKIGDFG+ + + E +YYR G PV W +PE L Sbjct 1139 LAAKKFVHRDLACRNCMVAQDRTVKIGDFGMTRDIYE-TDYYRKGGKGLLPVRWMSPESL 1197 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 K F SDVWS+GV L+E+ T L + + + + G Sbjct 1198 KVGVFTSQSDVWSYGVVLWEMAT--------------LASQPYQGKSNEEVLKFVIDGGM 1243 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 L +P+ CP ++Y LMK CW+ S RPTF ++ IL Sbjct 1244 LEKPEGCPNKLYDLMKLCWQYRQSMRPTFLEIVEILS 1280 Score = 233 bits (593), Expect = 5e-61, Method: Composition-based stats. Identities = 82/390 (21%), Positives = 143/390 (37%), Gaps = 67/390 (17%) Query 536 CLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQL---SFHRVDQKEITQL 592 LL F + C + G+ + A +P ++ + V +++IT + Sbjct 938 SLLLILAVIFGIWYCTKKRFGDKQMPNGVLYASVNPEYMSSDDVYVPDEWEVPREKITLI 997 Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH-DI 651 LGQG+ VYEG + +P + V +K ++ S Sbjct 998 RELGQGSFGMVYEGEAKDVVKDEPM-------------------VSVAVKTVNESASIRE 1038 Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH------ 705 + F AS+M + H+ + GV +G ++V E + G L +LRR R Sbjct 1039 RIEFLNEASVMKTFNCHHVVKLMGVVSKGQPTLVVMELMALGDLKNYLRRHRPEEDVGLS 1098 Query 706 -------------------VPMAWK--MVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 +P +K + +A +A +SYL K VH ++ RN ++A+ Sbjct 1099 DSPASNEAKNSPFAENDNDLPPTFKDIIQMAGVIADGMSYLAAKKFVHRDLACRNCMVAQ 1158 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKW 798 +K+ D G+ + + + W++PE L G ++ D W Sbjct 1159 -------DRTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKVGV--FTSQSDVW 1209 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQR 856 +G L E+ P Q +S E F L PE +L L C Y + R Sbjct 1210 SYGVVLWEMATLASQPYQGKSNEEVLKFVIDGGMLEKPEGCPNKLYDLMKLCWQYRQSMR 1269 Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 P+F I+ L+ + +V + Sbjct 1270 PTFLEIVEILSPELQAHFNEVSFYHSLDNH 1299 >sp|Q9SXB5|Y1135_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g11303 OS=Arabidopsis thaliana OX=3702 GN=At1g11303 PE=3 SV=1 Length=820 Score = 242 bits (618), Expect = 1e-65, Method: Composition-based stats. Identities = 75/278 (27%), Positives = 115/278 (41%), Gaps = 22/278 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG+G FG V G+ +AVK L G Q E+ ++ L H +++ Sbjct 513 NKLGQGGFGPVYKGMLLE-----GQEIAVKRLSQASG-QGLEELVTEVVVISKLQHRNLV 566 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA 1016 K GCC E+ LV E++P SL Y+ + IC G+ YLH Sbjct 567 KLFGCCIAGEER--MLVYEFMPKKSLDFYIFDPREAKLLDWNTRFEIINGICRGLLYLHR 624 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRDL A N+LLD + + KI DFGLA+ P + R + APE Sbjct 625 DSRLRIIHRDLKASNILLDENLIPKISDFGLARIFPGNEDEANTRR-VVGTYGYMAPEYA 683 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 F SDV+S GV L E+++ +S S L+ + +++ Sbjct 684 MGGLFSEKSDVFSLGVILLEIISGRRNSHST------LLAHVWSIWNEGEINGMVDPEIF 737 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +K + H+ C + A+ RP+ + +L + Sbjct 738 DQLFEKEIRKCVHIALLCVQDAANDRPSVSTVCMMLSS 775 Score = 232 bits (591), Expect = 3e-62, Method: Composition-based stats. Identities = 72/389 (19%), Positives = 122/389 (31%), Gaps = 63/389 (16%) Query 501 RLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGE--- 557 RL + QD +L G S+ + C+L A R E Sbjct 423 RLAHSEFKTQDRRPILIGT-----SLAGGIFVVATCVLLARRIVMKKRAKKKGTDAEQIF 477 Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 + G+R + L L + + + LGQG VY+G L Sbjct 478 KRVEALAGGSREKLKELPLFEFQVLATATDNFSLSNKLGQGGFGPVYKGMLLEGQ----- 532 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 + +K L + ++S++ H +L + G C Sbjct 533 --------------------EIAVKRLSQASGQGLEELVTEVVVISKLQHRNLVKLFGCC 572 Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVH 732 + G E ++V E++ LD ++ R + W + + + L YL ++H Sbjct 573 IAGEERMLVYEFMPKKSLDFYIFDPREAKLLDWNTRFEIINGICRGLLYLHRDSRLRIIH 632 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPG 786 ++ NILL + K+SD G+ + V ++APE G Sbjct 633 RDLKASNILLDE-------NLIPKISDFGLARIFPGNEDEANTRRVVGTYGYMAPEYAMG 685 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPL-------QSRSPSEKEHFYQRQH---RLPEP 836 G S D + G LLEI S + + +L E Sbjct 686 GL--FSEKSDVFSLGVILLEIISGRRNSHSTLLAHVWSIWNEGEINGMVDPEIFDQLFEK 743 Query 837 SCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + + C+ RPS T+ Sbjct 744 EIRKCVHIALLCVQDAANDRPSVSTVCMM 772 >sp|Q40541|NPK1_TOBAC Mitogen-activated protein kinase kinase kinase NPK1 OS=Nicotiana tabacum OX=4097 GN=NPK1 PE=1 SV=1 Length=690 Score = 239 bits (611), Expect = 1e-65, Method: Composition-based stats. Identities = 71/283 (25%), Positives = 129/283 (46%), Gaps = 28/283 (10%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-------ADCGPQHRSGWK 945 +K +G G FG+V + N +GE++A+K + + H + Sbjct 76 PPIRWRKGEMIGCGAFGRVYMGM----NVDSGELLAIKEVSIAMNGASRERAQAHVRELE 131 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFA 1004 +E+++L+ L H +I++Y G + G SL +++E+VP GS+ L + S + + ++ Sbjct 132 EEVNLLKNLSHPNIVRYLGTAREAG--SLNILLEFVPGGSISSLLGKFGSFPESVIRMYT 189 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 +Q+ G+ YLH +HRD+ N+L+DN +K+ DFG +K V E + +P Sbjct 190 KQLLLGLEYLHKNGIMHRDIKGANILVDNKGCIKLADFGASKKVVELATMTGAKSMKGTP 249 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 +W APE + + +++D+WS G T+ E+ T +Q V L Sbjct 250 -YWMAPEVILQTGHSFSADIWSVGCTIIEMATGKPP-------------WSQQYQEVAAL 295 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + P P+ E + C + E R + NL+ Sbjct 296 FHIGTTKSHPPIPEHLSAESKDFLLKCLQKEPHLRHSASNLLQ 338 Score = 193 bits (491), Expect = 4e-50, Method: Composition-based stats. Identities = 59/317 (19%), Positives = 102/317 (32%), Gaps = 39/317 (12%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 + +G G VY G G +E+ + + Sbjct 81 RKGEMIGCGAFGRVYMGMNVDSGELLAI-----------------KEVSIAMNGASRERA 123 Query 650 DIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 E +L+ +SH ++ G ++ E+V G + L + G P Sbjct 124 QAHVRELEEEVNLLKNLSHPNIVRYLGTAREAGSLNILLEFVPGGSISSLL-GKFGSFPE 182 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + + +QL L YL ++H ++ G NIL+ G IKL+D G + Sbjct 183 SVIRMYTKQLLLGLEYLHKNGIMHRDIKGANILVDNKG-------CIKLADFGASKKVVE 235 Query 769 REERV------ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 W+APE + +S S D W G T++E+ G+ P + Sbjct 236 LATMTGAKSMKGTPYWMAPEVILQTGHSFS--ADIWSVGCTIIEMA-TGKPPWSQQYQEV 292 Query 823 KEHFYQ----RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 F+ +PE + +CL EP R S +L+ H A Sbjct 293 AALFHIGTTKSHPPIPEHLSAESKDFLLKCLQKEPHLRHSASNLLQHPFVTAEHQEARPF 352 Query 879 TVNPDSPASDPTVFHKR 895 + + + Sbjct 353 LRSSFMGNPENMAAQRM 369 >sp|Q9S9M3|WAKLC_ARATH Wall-associated receptor kinase-like 3 OS=Arabidopsis thaliana OX=3702 GN=WAKL3 PE=2 SV=2 Length=730 Score = 240 bits (613), Expect = 1e-65, Method: Composition-based stats. Identities = 72/279 (26%), Positives = 116/279 (42%), Gaps = 20/279 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G G V G +VAVK K + EI +L + H +I+K Sbjct 434 LGQGGQGTVYKRML-----VDGSIVAVKRSKV-VDEDKMEEFINEIVLLSQINHRNIVKL 487 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGMAYLHAQ- 1017 GCC + E + LV EY+P G L L + + L A +I ++Y+H+ Sbjct 488 LGCCLE-TEVPI-LVYEYIPNGDLFKRLHDEYDDYMMTWEVRLRIAVEIAGALSYMHSAA 545 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 HRD+ N+LLD KI DFG +++V + + + PE Sbjct 546 SFPIFHRDIKTTNILLDEKYRAKISDFGTSRSVATDQTH--LTTLVAGTFGYMDPEYFLS 603 Query 1076 YKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 ++ + SDV+SFGV L EL+T S+ + + L M R ++++ R+ Sbjct 604 SQYTHKSDVYSFGVVLVELITGEKPMSRVRSEEGIGLATYFLEAMKENRAVDIID--IRI 661 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 K V L + C + + RP + L+ + Sbjct 662 KDESKQVMAVAKLARRCLNRKGNKRPNMREVSIKLERIR 700 Score = 223 bits (568), Expect = 7e-60, Method: Composition-based stats. Identities = 63/341 (18%), Positives = 114/341 (33%), Gaps = 61/341 (18%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + LGQG + VY+ L V +K Sbjct 424 ATDNFSIDRVLGQGGQGTVYKRMLVDGSI-------------------------VAVKRS 458 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D F L+SQ++H ++ + G C+ I+V EY+ +G L L E Sbjct 459 KVVDEDKMEEFINEIVLLSQINHRNIVKLLGCCLETEVPILVYEYIPNGDLFKRLHDEYD 518 Query 705 HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 M W ++ +A ++A ALSY+ + + H ++ NILL A K+SD Sbjct 519 DYMMTWEVRLRIAVEIAGALSYMHSAASFPIFHRDIKTTNILLDEKYRA-------KISD 571 Query 760 PGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G + + ++ PE ++ + D + FG L+E+ GE P Sbjct 572 FGTSRSVATDQTHLTTLVAGTFGYMDPEYFL--SSQYTHKSDVYSFGVVLVELI-TGEKP 628 Query 815 LQSRSPSE----------------KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPS 858 + E + + +A L +CL + +RP+ Sbjct 629 MSRVRSEEGIGLATYFLEAMKENRAVDIIDIRIKDESKQVMAVAKLARRCLNRKGNKRPN 688 Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899 R + L R++ + + + + + Sbjct 689 MREVSIKLERIRSSPKDLDVHTENEEEEEEDQLMEINRIYD 729 >sp|Q63796|M3K12_RAT Mitogen-activated protein kinase kinase kinase 12 OS=Rattus norvegicus OX=10116 GN=Map3k12 PE=1 SV=1 Length=888 Score = 243 bits (621), Expect = 1e-65, Method: Composition-based stats. Identities = 81/301 (27%), Positives = 122/301 (41%), Gaps = 35/301 (12%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + + D + ++ +G G G V L + GE VAVK Sbjct 132 WTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRFH------GEEVAVK 185 Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 ++ I LR L H +II +KG C ++ME+ G L + L Sbjct 186 KVRDLKETD--------IKHLRKLKHPNIITFKGVCTQA--PCYCILMEFCAQGQLYEVL 235 Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 + + L+ ++ I GM YLH IHRDL + N+L+ D +VKI DFG +K + Sbjct 236 RAGRPVTPSLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELS 295 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 + + V W APE ++ D+WSFGV L+ELLT P K + Sbjct 296 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG-----EIPYKDV 346 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + I G + LP P CP L++ CW + RP+F ++ L Sbjct 347 DSSAIIWGVGSN---------SLHLPVPSSCPDGFKILLRQCWNRKPRNRPSFRQILLHL 397 Query 1170 K 1170 Sbjct 398 D 398 Score = 202 bits (515), Expect = 3e-52, Method: Composition-based stats. Identities = 67/305 (22%), Positives = 109/305 (36%), Gaps = 50/305 (16%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 +A Q V +EI L +G G + V+ G Sbjct 136 GKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLG-------------------- 175 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 R G+E+ V KV D D + ++ H ++ GVC + P ++ Sbjct 176 ----RFHGEEVAVK-KVRDLKETD--------IKHLRKLKHPNIITFKGVCTQAPCYCIL 222 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 E+ G L LR R P + + + +A ++YL ++H ++ N+L+ Sbjct 223 MEFCAQGQLYEVLRAGRPVTP-SLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLIT--- 278 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +K+SD G + ++ + W+APE + +S +D W FG Sbjct 279 ----YDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 332 Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 L E+ GE P + S +P L QC +P RPSFR Sbjct 333 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNRKPRNRPSFR 391 Query 861 TILRD 865 IL Sbjct 392 QILLH 396 >sp|Q8TDX7|NEK7_HUMAN Serine/threonine-protein kinase Nek7 OS=Homo sapiens OX=9606 GN=NEK7 PE=1 SV=1 Length=302 Score = 227 bits (579), Expect = 1e-65, Method: Composition-based stats. Identities = 65/311 (21%), Positives = 118/311 (38%), Gaps = 30/311 (10%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + D + + +G G F +V Y G VA+K Sbjct 8 MQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEV----YRAACLLDGVPVALK 63 Query 931 ALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 ++ + R+ +EID+L+ L H ++IKY + E L +V+E G L Sbjct 64 KVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNE--LNIVLELADAGDLSR 121 Query 989 YLPRHS-----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 + I + + Q+C + ++H++ +HRD+ NV + +VK+GD G Sbjct 122 MIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLG 181 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 L + ++ +PE + E + + SD+WS G LYE+ Sbjct 182 LGRFFS---SKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYG 238 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRP-DKCPCEVYHLMKNCWETEASFRPTF 1162 +M + L + +E+ + P P D E+ L+ C + RP Sbjct 239 -------------DKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDV 285 Query 1163 ENLIPILKTVH 1173 + + K +H Sbjct 286 TYVYDVAKRMH 296 Score = 173 bits (438), Expect = 1e-46, Method: Composition-based stats. Identities = 48/299 (16%), Positives = 100/299 (33%), Gaps = 47/299 (16%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL--- 644 +G+G + VY ++G + V LK + Sbjct 33 NFRIEKKIGRGQFSEVYRAACLLDG------------------------VPVALKKVQIF 68 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD---VWLRR 701 D + L+ Q++H ++ + + E +V E + G L ++ Sbjct 69 DLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKK 128 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 ++ +P QL SAL ++ ++ ++H ++ N+ + G+ +KL D G Sbjct 129 QKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGV-------VKLGDLG 181 Query 762 VGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 +G S+ V +++PE + + D W G L E+ Sbjct 182 LGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNF--KSDIWSLGCLLYEMAALQSPFYGD 239 Query 818 RSPS----EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 + +K + +L L + C+ +P +RP + R+ Sbjct 240 KMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHAC 298 >sp|O65440|BAME3_ARATH Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM3 OS=Arabidopsis thaliana OX=3702 GN=BAM3 PE=1 SV=3 Length=992 Score = 244 bits (624), Expect = 1e-65, Method: Composition-based stats. Identities = 74/319 (23%), Positives = 133/319 (42%), Gaps = 23/319 (7%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-K 933 ++ + + +K+ +G+G G V GE VAVK L Sbjct 688 PNLWKLIGFQKLGFRSEHILECVKENHVIGKGGRGIVYKGV-----MPNGEEVAVKKLLT 742 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993 G H +G EI L + H +I++ C ++ LV EY+P GSL + L Sbjct 743 ITKGSSHDNGLAAEIQTLGRIRHRNIVRLLAFCSNKDVN--LLVYEYMPNGSLGEVLHGK 800 Query 994 S---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 + + L A + +G+ YLH IHRD+ + N+LL + + DFGLAK Sbjct 801 AGVFLKWETRLQIALEAAKGLCYLHHDCSPLIIHRDVKSNNILLGPEFEAHVADFGLAKF 860 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + + + + APE + SDV+SFGV L EL+T + + Sbjct 861 MMQDNGASECMSSIAGSYGYIAPEYAYTLRIDEKSDVYSFGVVLLELITGRKPVDNFGEE 920 Query 1108 FLELIGIAQGQMTVLR--LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 ++++ ++ Q R + +++++ P E++ + C + + RPT + Sbjct 921 GIDIVQWSKIQTNCNRQGVVKIIDQRLSN-IPLAEAMELFFVAMLCVQEHSVERPTMREV 979 Query 1166 IPILKTVHEKYQGQAPSVF 1184 + ++ Q + P+ F Sbjct 980 VQMIS------QAKQPNTF 992 Score = 189 bits (480), Expect = 1e-47, Method: Composition-based stats. Identities = 54/280 (19%), Positives = 94/280 (34%), Gaps = 53/280 (19%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---- 644 + + +G+G R VY+G + V +K L Sbjct 710 VKENHVIGKGGRGIVYKGVMPNGE-------------------------EVAVKKLLTIT 744 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 S HD LA + ++ H ++ + C N++V EY+ +G L L + G Sbjct 745 KGSSHDNGLA--AEIQTLGRIRHRNIVRLLAFCSNKDVNLLVYEYMPNGSLGEVLHGKAG 802 Query 705 -HVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + ++ +A + A L YL + ++H +V NILL G ++D Sbjct 803 VFLKWETRLQIALEAAKGLCYLHHDCSPLIIHRDVKSNNILL-------GPEFEAHVADF 855 Query 761 GVGLGALSR-------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ + ++APE + D + FG LLE+ G Sbjct 856 GLAKFMMQDNGASECMSSIAGSYGYIAPEYA--YTLRIDEKSDVYSFGVVLLELI-TGRK 912 Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEP 853 P E Q + + + Q L+ P Sbjct 913 P-VDNFGEEGIDIVQWSKIQTNCNRQGVVKIIDQRLSNIP 951 >sp|O22476|BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 OS=Arabidopsis thaliana OX=3702 GN=BRI1 PE=1 SV=1 Length=1196 Score = 246 bits (629), Expect = 1e-65, Method: Composition-based stats. Identities = 74/287 (26%), Positives = 122/287 (43%), Gaps = 20/287 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +G G FG V G VA+K L G R + E++ + + H Sbjct 883 FHNDSLIGSGGFGDVYKAILK-----DGSAVAIKKLIHVSGQGDRE-FMAEMETIGKIKH 936 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGM 1011 +++ G C+ E+ LV E++ GSL D L + + A G+ Sbjct 937 RNLVPLLGYCKVGDER--LLVYEFMKYGSLEDVLHDPKKAGVKLNWSTRRKIAIGSARGL 994 Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 A+LH H IHRD+ + NVLLD + ++ DFG+A+ + + V +P + Sbjct 995 AFLHHNCSPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTP-GYV 1053 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE + ++ DV+S+GV L ELLT + SP L+G + Q LR++++ Sbjct 1054 PPEYYQSFRCSTKGDVYSYGVVLLELLTGKRPTDSPDFGDNNLVGWVK-QHAKLRISDVF 1112 Query 1129 ERGERLPRPDKCPCEVYHL--MKNCWETEASFRPTFENLIPILKTVH 1173 + P + HL C + A RPT ++ + K + Sbjct 1113 DPELMKEDPALEIELLQHLKVAVACLDDRAWRRPTMVQVMAMFKEIQ 1159 Score = 213 bits (542), Expect = 6e-55, Method: Composition-based stats. Identities = 57/370 (15%), Positives = 120/370 (32%), Gaps = 60/370 (16%) Query 576 LSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L +L+F + S +G G +VY+ L+ Sbjct 868 LRKLTFADLLQATNGFHNDSLIGSGGFGDVYKAILKDGS--------------------- 906 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 V +K L F + ++ H +L + G C G E ++V E++++G Sbjct 907 ----AVAIKKLIHVSGQGDREFMAEMETIGKIKHRNLVPLLGYCKVGDERLLVYEFMKYG 962 Query 694 PLDVWLRRERG---HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGL 747 L+ L + + + + +A A L++L + +++H ++ N+LL Sbjct 963 SLEDVLHDPKKAGVKLNWSTRRKIAIGSARGLAFLHHNCSPHIIHRDMKSSNVLLDE--- 1019 Query 748 AEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 + ++SD G+ LS ++ PE + ST D + +G Sbjct 1020 ----NLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQ--SFRCSTKGDVYSYG 1073 Query 802 ATLLEICFDGEA---PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT-QRP 857 LLE+ P + + R+ + P+L +P + Sbjct 1074 VVLLELLTGKRPTDSPDFGDNNLVGWVKQHAKLRISDVFDPELMK-------EDPALEIE 1126 Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI-RDLGEGHFGKVSLYCY 916 + + + L V + + + R + +G F + + Sbjct 1127 LLQHLKVAVACLDDRAWRRPTMVQVMAMFKEIQAGSGIDSQSTIRSIEDGGFSTIEMVDM 1186 Query 917 DPTNDGTGEM 926 G++ Sbjct 1187 SIKEVPEGKL 1196 >sp|D3ZBE5|NEK7_RAT Serine/threonine-protein kinase Nek7 OS=Rattus norvegicus OX=10116 GN=Nek7 PE=1 SV=1 Length=302 Score = 227 bits (579), Expect = 1e-65, Method: Composition-based stats. Identities = 65/311 (21%), Positives = 119/311 (38%), Gaps = 30/311 (10%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + D + + +G G F +V Y + G VA+K Sbjct 8 MQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEV----YRASCLLDGVPVALK 63 Query 931 ALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 ++ + R+ +EID+L+ L H ++IKY + E L +V+E G L Sbjct 64 KVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNE--LNIVLELADAGDLSR 121 Query 989 YLPRHS-----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 + I + + Q+C + ++H++ +HRD+ NV + +VK+GD G Sbjct 122 MIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLG 181 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 L + ++ +PE + E + + SD+WS G LYE+ Sbjct 182 LGRFFS---SKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYG 238 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRP-DKCPCEVYHLMKNCWETEASFRPTF 1162 +M + L + +E+ + P P D E+ L+ C + RP Sbjct 239 -------------DKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDI 285 Query 1163 ENLIPILKTVH 1173 + + K +H Sbjct 286 AYVYDVAKRMH 296 Score = 171 bits (433), Expect = 6e-46, Method: Composition-based stats. Identities = 48/299 (16%), Positives = 100/299 (33%), Gaps = 47/299 (16%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL--- 644 +G+G + VY ++G + V LK + Sbjct 33 NFRIEKKIGRGQFSEVYRASCLLDG------------------------VPVALKKVQIF 68 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD---VWLRR 701 D + L+ Q++H ++ + + E +V E + G L ++ Sbjct 69 DLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKK 128 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 ++ +P QL SAL ++ ++ ++H ++ N+ + G+ +KL D G Sbjct 129 QKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGV-------VKLGDLG 181 Query 762 VGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 +G S+ V +++PE + + D W G L E+ Sbjct 182 LGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNF--KSDIWSLGCLLYEMAALQSPFYGD 239 Query 818 RSPS----EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 + +K + +L L + C+ +P +RP + R+ Sbjct 240 KMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHAC 298 >sp|Q5MD89|VGFR3_DANRE Vascular endothelial growth factor receptor 3 OS=Danio rerio OX=7955 GN=flt4 PE=2 SV=1 Length=1357 Score = 247 bits (631), Expect = 1e-65, Method: Composition-based stats. Identities = 89/361 (25%), Positives = 142/361 (39%), Gaps = 69/361 (19%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG-EMV 927 + P + S + L+ + LG G FGKV + + V Sbjct 838 MDPGEVPLEEQCEYLPYDSSQWEISRDRLRLGKVLGHGAFGKVIEASIFGHDKKSSANTV 897 Query 928 AVKALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 AVK LK E+ IL + H +++ G C + +V EY G+L Sbjct 898 AVKMLKEGATASEHKALMSELKILIHIGNHLNVVNLLGACTKPNGPLMVIV-EYCKYGNL 956 Query 987 RDYLP----------------------------------------------------RHS 994 ++L + Sbjct 957 SNFLRAKREFFLPYRDRSPKTQSQVRRMIEAGQASQSEHQPSTSSTNPPRVTVDDLWKTP 1016 Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + + L+ ++ Q+ GM +L ++ IHRDLAARN+LL + +VKI DFGLA+ + + +Y Sbjct 1017 LTIEDLICYSFQVARGMEFLASRKCIHRDLAARNILLSENNVVKICDFGLARDIYKDPDY 1076 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 R + + P+ W APE + + + SDVWSFGV L+E+ + S Sbjct 1077 VR-KGNARLPLKWMAPESIFDKVYTSQSDVWSFGVLLWEIFSLGASPY------------ 1123 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 G + L+ G R+ PD E+Y +M CW+ E RPTF L+ IL + + Sbjct 1124 -PGIQIDEDFCKRLKDGTRMRAPDNASPEIYGIMLACWQGEPRERPTFPALVEILGDLLQ 1182 Query 1175 K 1175 + Sbjct 1183 E 1183 Score = 212 bits (540), Expect = 1e-54, Method: Composition-based stats. Identities = 61/366 (17%), Positives = 119/366 (33%), Gaps = 90/366 (25%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 S + + + LG G V E + + Sbjct 855 DSSQWEISRDRLRLGKVLGHGAFGKVIEASIFGHDK-------------------KSSAN 895 Query 638 RVVLKVLDPS-HHDIALAFYETASLMSQV-SHTHLAFVHGVCVRG-PENIMVTEYVEHGP 694 V +K+L A ++ + +H ++ + G C + +++ EY ++G Sbjct 896 TVAVKMLKEGATASEHKALMSELKILIHIGNHLNVVNLLGACTKPNGPLMVIVEYCKYGN 955 Query 695 LDVWLRRER--------------------------------------------------G 704 L +LR +R Sbjct 956 LSNFLRAKREFFLPYRDRSPKTQSQVRRMIEAGQASQSEHQPSTSSTNPPRVTVDDLWKT 1015 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + + + Q+A + +L ++ +H ++ RNILL+ + +K+ D G+ Sbjct 1016 PLTIEDLICYSFQVARGMEFLASRKCIHRDLAARNILLSENNV-------VKICDFGLAR 1068 Query 765 GALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + + W+APE + ++ D W FG L EI G +P Sbjct 1069 DIYKDPDYVRKGNARLPLKWMAPESIFDKV--YTSQSDVWSFGVLLWEIFSLGASPYPGI 1126 Query 819 SPSE---KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 E K + R P+ + P++ + C EP +RP+F ++ L L N Sbjct 1127 QIDEDFCKRLKDGTRMRAPDNASPEIYGIMLACWQGEPRERPTFPALVEILGDLLQENSL 1186 Query 876 DVLTVN 881 + N Sbjct 1187 PEIPFN 1192 >sp|Q99JT2|STK26_MOUSE Serine/threonine-protein kinase 26 OS=Mus musculus OX=10090 GN=Stk26 PE=1 SV=1 Length=416 Score = 231 bits (590), Expect = 1e-65, Method: Composition-based stats. Identities = 72/294 (24%), Positives = 123/294 (42%), Gaps = 24/294 (8%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933 +A + + K+ +G+G FG+V + ++ T ++VA+K + Sbjct 1 MAHSPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEV----FKGIDNRTQQVVAIKIID 56 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993 + +QEI +L ++ KY G + L ++MEY+ GS D L Sbjct 57 LEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSK--LWIIMEYLGGGSALDLLRAG 114 Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 Q+ ++I +G+ YLH++ IHRD+ A NVLL VK+ DFG+A + + Sbjct 115 PFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD--- 171 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 R FW APE +++ + +D+WS G+T EL + PP Sbjct 172 TQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIEL-----AKGEPP-------- 218 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 M +R+ L+ + + C + SFRPT + L+ Sbjct 219 --NSDMHPMRVLFLIPKNNPPTLIGDFTKSFKEFIDACLNKDPSFRPTAKELLK 270 Score = 209 bits (532), Expect = 6e-58, Method: Composition-based stats. Identities = 61/310 (20%), Positives = 119/310 (38%), Gaps = 44/310 (14%) Query 570 SPRTLNLSQLSFHRVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 SP + + + + D +E T+L +G+G+ V++G Sbjct 4 SPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGI--------------------- 42 Query 629 PGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 D + V +K++D D + +++SQ +++ +G ++G + ++ Sbjct 43 ---DNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIM 99 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 EY+ G LR G + +++ L YL ++ +H ++ N+LL+ G Sbjct 100 EYLGGGSALDLLRA--GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGD 157 Query 748 AEGTSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +KL+D GV + R V W+APE + A + D W G T Sbjct 158 -------VKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSA--YDSKADIWSLGIT 208 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861 +E+ GE P P + + L CL +P+ RP+ + Sbjct 209 AIELA-KGEPPNSDMHPMRVLFLIPKNNPPTLIGDFTKSFKEFIDACLNKDPSFRPTAKE 267 Query 862 ILRDLTRLQP 871 +L+ ++ Sbjct 268 LLKHKFIVKN 277 >sp|Q86HG9|Y9871_DICDI Probable serine/threonine-protein kinase DDB_G0271682 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0271682 PE=3 SV=2 Length=1024 Score = 245 bits (625), Expect = 1e-65, Method: Composition-based stats. Identities = 77/280 (28%), Positives = 125/280 (45%), Gaps = 38/280 (14%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G G+V Y + G VAVK + K+ + +++E+ IL+ L H +++ Sbjct 365 KIGSGACGEVCQYEWK------GTPVAVKTIFKSLLRKDKKEEFEKEVSILKCLRHPNVV 418 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH-- 1015 + G C G +L ++ EY+ GSLRD L + + L+ + + +GM YLH Sbjct 419 LFMGTCLLNG--NLAIITEYLNRGSLRDVLTTMNKSELSLSVKVKMLIDVAQGMNYLHTY 476 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + IHRDL + N+L+DN+ VK+ DFGL++ + G + + W APE Sbjct 477 SPPIIHRDLKSLNLLVDNNFNVKVSDFGLSRFISGGIG--SSAKTFCGTLSWIAPEVFNG 534 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + DV+SFG+ L+E+LTH S + L Sbjct 535 SGYTTKVDVYSFGIVLWEILTHKQPSGNISATSL----------------------GHPE 572 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 P CP L+K C RP F ++ LK ++ + Sbjct 573 LPSNCPQSFSDLIKECCNRNPDQRPNFSQILLKLKLMYNQ 612 Score = 202 bits (513), Expect = 1e-51, Method: Composition-based stats. Identities = 60/315 (19%), Positives = 115/315 (37%), Gaps = 51/315 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + + E+ + +G G V + + V +K Sbjct 355 IQENELLFIKKIGSGACGEVCQYEWKG--------------------------TPVAVKT 388 Query 644 LDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL-R 700 + S D F + S++ + H ++ G C+ ++TEY+ G L L Sbjct 389 IFKSLLRKDKKEEFEKEVSILKCLRHPNVVLFMGTCLLNGNLAIITEYLNRGSLRDVLTT 448 Query 701 RERGHVPMAWKMVVAQQLASALSYLE--NKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + + ++ K+ + +A ++YL + ++H ++ N+L+ + +K+S Sbjct 449 MNKSELSLSVKVKMLIDVAQGMNYLHTYSPPIIHRDLKSLNLLVDN-------NFNVKVS 501 Query 759 DPGVGLGA-----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 D G+ S + + W+APE G + +T +D + FG L EI + Sbjct 502 DFGLSRFISGGIGSSAKTFCGTLSWIAPEVFNG--SGYTTKVDVYSFGIVLWEILTH-KQ 558 Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 P + S + H LP + L +C P QRP+F IL L + Sbjct 559 PSGNISATSLGH-----PELPSNCPQSFSDLIKECCNRNPDQRPNFSQILLKLKLMYNQI 613 Query 874 LADVLTVNPDSPASD 888 + DS + Sbjct 614 NNNNNNNKIDSSSFH 628 Score = 84.7 bits (208), Expect = 4e-15, Method: Composition-based stats. Identities = 29/143 (20%), Positives = 60/143 (42%), Gaps = 12/143 (8%) Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 N+ N+ +K+ DFGL++ + +E ++ + PE L + SD++S Sbjct 885 NI---NEIKIKVHDFGLSRFNTQENE--ESLKEIKGNFLYSPPELLSLNTYSNKSDIYSL 939 Query 1088 GVTLYELL-THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 + LYEL T + P + L + + + R + P E+ Sbjct 940 SIVLYELFETCLTKTYKKPYHEVTL------DFDFQIIHKTSKLNLRPTISNNMPNEISK 993 Query 1147 LMKNCWETEASFRPTFENLIPIL 1169 +++ W +++ RP+ + +I L Sbjct 994 ILQQGWFSDSVLRPSLDTIIKEL 1016 Score = 70.5 bits (171), Expect = 9e-11, Method: Composition-based stats. Identities = 21/138 (15%), Positives = 58/138 (42%), Gaps = 9/138 (7%) Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667 ++ + + + D ++ G+ +G+ V +K ++ S +D + +++ + Sbjct 687 IQPNEITNIKTIIVKDSYSILEGQYKGK--LVSIKQINGSINDFEMKQLG---VLASIKS 741 Query 668 THLAFVHGVCVRGPENIMVTEYV-EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726 GV E +++E+V +G L ++ + + + +A Q+ ++ YL Sbjct 742 PLAVRFIGVVFNTDEYAIISEHVGNNGSLLTLMQNHSNQLNWSNTIDLAIQITQSIQYLH 801 Query 727 NK--NLVHGNVCGRNILL 742 ++H N+ + L Sbjct 802 KHQPPILHRNI-TSDCFL 818 Score = 65.5 bits (158), Expect = 2e-09, Method: Composition-based stats. Identities = 23/115 (20%), Positives = 49/115 (43%), Gaps = 11/115 (10%) Query 924 GEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV-P 982 G++V++K + +L ++ +++ G + E ++ E+V Sbjct 713 GKLVSIKQINGSINDFEMKQL----GVLASIKSPLAVRFIGVVFNTDE--YAIISEHVGN 766 Query 983 LGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLDN 1033 GSL + HS + + + A QI + + YLH +HR++ + LL + Sbjct 767 NGSLLTLMQNHSNQLNWSNTIDLAIQITQSIQYLHKHQPPILHRNITSDCFLLSS 821 Score = 53.5 bits (127), Expect = 1e-05, Method: Composition-based stats. Identities = 22/136 (16%), Positives = 44/136 (32%), Gaps = 18/136 (13%) Query 755 IKLSDPGVGLGAL-----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 IK+ D G+ S +E + PE L N+ S D + L E+ Sbjct 891 IKVHDFGLSRFNTQENEESLKEIKGNFLYSPPELLS--LNTYSNKSDIYSLSIVLYELFE 948 Query 810 DG-----EAPLQSRSPSEKEHFYQR------QHRLPEPSCPQLATLTSQCLTYEPTQRPS 858 + P + + + + +++ + Q + RPS Sbjct 949 TCLTKTYKKPYHEVTLDFDFQIIHKTSKLNLRPTISNNMPNEISKILQQGWFSDSVLRPS 1008 Query 859 FRTILRDLTRLQPHNL 874 TI+++L + + Sbjct 1009 LDTIIKELLICKKNLC 1024 >sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens OX=9606 GN=LIMK1 PE=1 SV=3 Length=647 Score = 238 bits (607), Expect = 1e-65, Method: Composition-based stats. Identities = 74/309 (24%), Positives = 132/309 (43%), Gaps = 33/309 (11%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 +F L LG+G FG+ T+ TGE++ +K L + + + Sbjct 328 CRPHRIFRPSDLIHGEVLGKGCFGQ----AIKVTHRETGEVMVMKEL-IRFDEETQRTFL 382 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLF 1003 +E+ ++R L H +++K+ G +K L + EY+ G+LR + +Q + F Sbjct 383 KEVKVMRCLEHPNVLKFIGVLYK--DKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSF 440 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY--------- 1054 A+ I GMAYLH+ + IHRDL + N L+ ++ V + DFGLA+ + + Sbjct 441 AKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKK 500 Query 1055 --YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 + R +W APE + + DV+SFG+ L E++ ++ + ++ Sbjct 501 PDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFG 560 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +G + P CP + + C + + RP+F L L+T+ Sbjct 561 LNVRGFLDRY-------------CPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETL 607 Query 1173 HEKYQGQAP 1181 G P Sbjct 608 RMHLAGHLP 616 Score = 210 bits (534), Expect = 4e-56, Method: Composition-based stats. Identities = 70/396 (18%), Positives = 134/396 (34%), Gaps = 57/396 (14%) Query 501 RLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSN 560 RL + +E + G G + G + LR C + + + Sbjct 248 RLLQLTLEHDPHDTLGHGLGPETSPLSSPAYTPSGEAGSSARQKPVLRSCSIDRSPGAGS 307 Query 561 L---IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 L R +L + ++ LG+G + R G Sbjct 308 LGSPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGE---- 363 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 +V+K L + F + +M + H ++ GV Sbjct 364 --------------------VMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVL 403 Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737 + +TEY++ G L ++ P + ++ A+ +AS ++YL + N++H ++ Sbjct 404 YKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNS 463 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------------------VERIPWL 779 N L+ + + ++D G+ + + + V W+ Sbjct 464 HNCLVRE-------NKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWM 516 Query 780 APECLPGGANSLSTAMDKWGFGATLLEIC--FDGEAPLQSRSPSEKEHFYQRQHRLPEPS 837 APE + G S +D + FG L EI + + R+ + R P+ Sbjct 517 APEMING--RSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPN 574 Query 838 CPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 CP +T +C +P +RPSF + L L+ H Sbjct 575 CPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMH 610 >sp|P04626|ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 OS=Homo sapiens OX=9606 GN=ERBB2 PE=1 SV=1 Length=1255 Score = 247 bits (630), Expect = 1e-65, Method: Composition-based stats. Identities = 87/272 (32%), Positives = 133/272 (49%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + VA+K L+ + P+ E ++ + ++ + Sbjct 726 LGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRL 785 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C +QLV + +P G L D++ R +G LL + QI +GM+YL + Sbjct 786 LGICLTST---VQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLV 842 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W A E + +F + Sbjct 843 HRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWMALESILRRRFTH 901 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + + +LLE+GERLP+P C Sbjct 902 QSDVWSYGVTVWELMTFG--------------AKPYDGIPAREIPDLLEKGERLPQPPIC 947 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW ++ RP F L+ + Sbjct 948 TIDVYMIMVKCWMIDSECRPRFRELVSEFSRM 979 Score = 224 bits (570), Expect = 2e-58, Method: Composition-based stats. Identities = 82/474 (17%), Positives = 163/474 (34%), Gaps = 49/474 (10%) Query 419 LVDGYFRLTADSSHYL-CHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHW-S 476 ++ G R ++ H L CH P + GP + V + + S Sbjct 546 VLQGLPREYVNARHCLPCHPECQP---QNGSVTCFGPEADQCVACAHYKDPPFCVARCPS 602 Query 477 TSHPYRLILTVAQRSQAPDGMQSLRL--RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQ 534 P + + + Q + ++ D E S+ + Sbjct 603 GVKPDLSYMPIWKFPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVGIL 662 Query 535 GCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL---SQLSFHRVDQKEITQ 591 ++ ++R T ++ P T + +Q + + E+ + Sbjct 663 LVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRK 722 Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-HHD 650 + LG G VY+G +G ++ V +KVL + Sbjct 723 VKVLGSGAFGTVYKGIWIPDGENV--------------------KIPVAIKVLRENTSPK 762 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 + A +M+ V +++ + G+C+ +VT+ + +G L +R RG + Sbjct 763 ANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQLMPYGCLLDHVRENRGRLGSQD 821 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------ 764 + Q+A +SYLE+ LVH ++ RN+L+ +K++D G+ Sbjct 822 LLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPN-------HVKITDFGLARLLDIDE 874 Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + I W+A E + + D W +G T+ E+ G P E Sbjct 875 TEYHADGGKVPIKWMALESIL--RRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIP 932 Query 825 HFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 ++ RLP+P + + +C + RP FR ++ + +R+ Sbjct 933 DLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRF 986 >sp|Q9ZVR7|PSKR1_ARATH Phytosulfokine receptor 1 OS=Arabidopsis thaliana OX=3702 GN=PSKR1 PE=1 SV=4 Length=1008 Score = 244 bits (624), Expect = 1e-65, Method: Composition-based stats. Identities = 78/279 (28%), Positives = 119/279 (43%), Gaps = 19/279 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V Y T G+ VA+K L DCG R ++ E++ L H +++ Sbjct 740 IGCGGFGMV----YKATLPD-GKKVAIKKLSGDCGQIERE-FEAEVETLSRAQHPNLVLL 793 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHA- 1016 +G C + ++ L+ Y+ GSL +L + + L AQ +G+ YLH Sbjct 794 RGFCFYKNDR--LLIYSYMENGSLDYWLHERNDGPALLKWKTRLRIAQGAAKGLLYLHEG 851 Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H +HRD+ + N+LLD + + DFGLA+ + + V D + + PE + Sbjct 852 CDPHILHRDIKSSNILLDENFNSHLADFGLARLMSPYETH--VSTDLVGTLGYIPPEYGQ 909 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQMTVLRLTELLERGER 1133 Y DV+SFGV L ELLT P +LI R +E+ + Sbjct 910 ASVATYKGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHESRASEVFDPLIY 969 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 DK V + C RPT + L+ L V Sbjct 970 SKENDKEMFRVLEIACLCLSENPKQRPTTQQLVSWLDDV 1008 Score = 217 bits (553), Expect = 1e-56, Method: Composition-based stats. Identities = 65/321 (20%), Positives = 110/321 (34%), Gaps = 64/321 (20%) Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 N +LS+ + Q + +G G VY+ L Sbjct 718 NDKELSYDDLLDSTNSFDQANIIGCGGFGMVYKATLPDGK-------------------- 757 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 +V +K L I F +S+ H +L + G C + +++ Y+E+ Sbjct 758 -----KVAIKKLSGDCGQIEREFEAEVETLSRAQHPNLVLLRGFCFYKNDRLLIYSYMEN 812 Query 693 GPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLG 746 G LD WL R G + W ++ +AQ A L YL +++H ++ NILL Sbjct 813 GSLDYWLHERNDGPALLKWKTRLRIAQGAAKGLLYLHEGCDPHILHRDIKSSNILLDE-- 870 Query 747 LAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFG 801 + L+D G+ E V + ++ PE + D + FG Sbjct 871 -----NFNSHLADFGLARLMSPYETHVSTDLVGTLGYIPPEYGQASVATY--KGDVYSFG 923 Query 802 ATLLEICFDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLA------------TL 844 LLE+ D P R + + R E P + + Sbjct 924 VVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHESRASEVFDPLIYSKENDKEMFRVLEI 983 Query 845 TSQCLTYEPTQRPSFRTILRD 865 CL+ P QRP+ + ++ Sbjct 984 ACLCLSENPKQRPTTQQLVSW 1004 >sp|P0CD62|LIMKB_DICDI Probable LIM domain-containing serine/threonine-protein kinase DDB_G0286997 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0286997 PE=3 SV=1 Length=966 Score = 244 bits (623), Expect = 1e-65, Method: Composition-based stats. Identities = 73/310 (24%), Positives = 125/310 (40%), Gaps = 30/310 (10%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 L+ D++ + S K + + G GKV Y + VA Sbjct 674 LKHQTFDDIVGEVLNKRISIYKQLVKDDVIFGDVIAAGASGKVYKGIYKGRD------VA 727 Query 929 VKALKADCGPQHRSGWKQEIDILRTLY--HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 +K ++ + + +E+ I+ + H + ++ G Q +K L V E V GSL Sbjct 728 IKVYSSENFCFNIDEFDREVTIMSLIDSDHPNFTRFYGA-NKQNKKYLFHVSELVKSGSL 786 Query 987 RDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 RD L + L A I M +LH+ IHRDL + NVL+ D K+ DFG Sbjct 787 RDLLLDKEKPLLYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITEDFTAKVIDFGT 846 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 ++ V + + + +PE K + DV++FG+ L+E++ + Sbjct 847 SRNV----DLAKHMTMNLGTSCYMSPELFKGNGYDETCDVYAFGIVLWEIIARKEP---- 898 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + + ++ +G+R P CP E L+K CW + RP+F+ Sbjct 899 -----------YENINSWSIPVMVAKGDRPTIPADCPSEYSKLIKACWTDKPKKRPSFKE 947 Query 1165 LIPILKTVHE 1174 + LK + E Sbjct 948 ICDTLKKISE 957 Score = 178 bits (451), Expect = 3e-44, Method: Composition-based stats. Identities = 57/305 (19%), Positives = 112/305 (37%), Gaps = 45/305 (15%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 LN + ++ + ++ + G VY+G + GRD Sbjct 687 LNKRISIYKQLVKDDVIFGDVIAAGASGKVYKG--------------------IYKGRD- 725 Query 634 GQELRVVLKVLDPSHHDI-ALAFYETASLMSQVS--HTHLAFVHGVCVRGPENIM-VTEY 689 V +KV + F ++MS + H + +G + + + V+E Sbjct 726 -----VAIKVYSSENFCFNIDEFDREVTIMSLIDSDHPNFTRFYGANKQNKKYLFHVSEL 780 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 V+ G L L + + ++ +A +A+A+ +L + ++H ++ N+L+ Sbjct 781 VKSGSLRDLLLDKEKPLLYFTQLSIASDIANAMKHLHSIGVIHRDLKSLNVLITE----- 835 Query 750 GTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 K+ D G + +++PE G N D + FG L E Sbjct 836 --DFTAKVIDFGTSRNVDLAKHMTMNLGTSCYMSPELFKG--NGYDETCDVYAFGIVLWE 891 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 I E P ++ + + R +P + + L C T +P +RPSF+ I Sbjct 892 IIARKE-PYENINSWSIPVMVAKGDRPTIPADCPSEYSKLIKACWTDKPKKRPSFKEICD 950 Query 865 DLTRL 869 L ++ Sbjct 951 TLKKI 955 >sp|Q8LPB4|PSKR1_DAUCA Phytosulfokine receptor 1 OS=Daucus carota OX=4039 GN=PSKR PE=1 SV=1 Length=1021 Score = 244 bits (624), Expect = 1e-65, Method: Composition-based stats. Identities = 77/279 (28%), Positives = 118/279 (42%), Gaps = 19/279 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V Y T G VA+K L D G R ++ E++ L H +++ Sbjct 749 IGCGGFGLV----YKATLPD-GTKVAIKRLSGDTGQMDRE-FQAEVETLSRAQHPNLVHL 802 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLH-- 1015 G C + +K L+ Y+ GSL +L S+ L A+ EG+AYLH Sbjct 803 LGYCNYKNDK--LLIYSYMDNGSLDYWLHEKVDGPPSLDWKTRLRIARGAAEGLAYLHQS 860 Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H +HRD+ + N+LL + + + DFGLA+ + + V D + + PE + Sbjct 861 CEPHILHRDIKSSNILLSDTFVAHLADFGLARLILPYDTH--VTTDLVGTLGYIPPEYGQ 918 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIAQGQMTVLRLTELLERGER 1133 Y DV+SFGV L ELLT P +LI T R +E+ + Sbjct 919 ASVATYKGDVYSFGVVLLELLTGRRPMDVCKPRGSRDLISWVLQMKTEKRESEIFDPFIY 978 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + V + C RPT + L+ L+ + Sbjct 979 DKDHAEEMLLVLEIACRCLGENPKTRPTTQQLVSWLENI 1017 Score = 219 bits (557), Expect = 5e-57, Method: Composition-based stats. Identities = 61/325 (19%), Positives = 114/325 (35%), Gaps = 66/325 (20%) Query 577 SQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 ++LS + Q + +G G VY+ L Sbjct 729 NELSLDDILKSTSSFNQANIIGCGGFGLVYKATLPDG----------------------- 765 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 +V +K L + F +S+ H +L + G C + +++ Y+++G Sbjct 766 --TKVAIKRLSGDTGQMDREFQAEVETLSRAQHPNLVHLLGYCNYKNDKLLIYSYMDNGS 823 Query 695 LDVWLRRE-RGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLA 748 LD WL + G + W ++ +A+ A L+YL +++H ++ NILL+ +A Sbjct 824 LDYWLHEKVDGPPSLDWKTRLRIARGAAEGLAYLHQSCEPHILHRDIKSSNILLSDTFVA 883 Query 749 EGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 L+D G+ L + V + ++ PE + D + FG Sbjct 884 H-------LADFGLARLILPYDTHVTTDLVGTLGYIPPEYGQASVATY--KGDVYSFGVV 934 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQR------QHRLPEPSCPQLAT------------LT 845 LLE+ G P+ P + R E P + + Sbjct 935 LLELL-TGRRPMDVCKPRGSRDLISWVLQMKTEKRESEIFDPFIYDKDHAEEMLLVLEIA 993 Query 846 SQCLTYEPTQRPSFRTILRDLTRLQ 870 +CL P RP+ + ++ L + Sbjct 994 CRCLGENPKTRPTTQQLVSWLENID 1018 >sp|Q8BYG9|EPHAA_MOUSE Ephrin type-A receptor 10 OS=Mus musculus OX=10090 GN=Epha10 PE=2 SV=2 Length=1007 Score = 244 bits (624), Expect = 1e-65, Method: Composition-based stats. Identities = 89/277 (32%), Positives = 127/277 (46%), Gaps = 23/277 (8%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEM-VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG G FG + C G E+ VAV L+ C R + E L H HI+ Sbjct 649 SLGAGRFGTLCCGCLQ--LPGRQELPVAVHTLRDGCSDSQRLSFLAEALTLGQFDHSHIV 706 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQH 1018 + +G L +V EY+ LG+L D+L H L AQL+ + M YL Sbjct 707 RLEGVVTRGN--PLMIVTEYMNLGALDDFLRHHEGELVAAQLMGLLPGLASAMKYLSEMG 764 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 Y+HR LAAR VL+ + L KI FG + + E G SP W APE L+ F Sbjct 765 YVHRGLAARRVLVSSGLLCKISGFG--RGPRDRAEAVYTTMSGRSPALWAAPETLQFGHF 822 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 ASDVWSFG+ ++E++ + M+ + + +E G RLP P Sbjct 823 SSASDVWSFGIVMWEVMAFGER--------------PYWDMSGQDVIKAVEDGFRLPPPR 868 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 CP +++ LM CW+ + S RP F + IL + ++ Sbjct 869 NCPSQLHRLMLECWQKDPSERPRFSQIHSILSKMGQE 905 Score = 234 bits (596), Expect = 5e-62, Method: Composition-based stats. Identities = 99/391 (25%), Positives = 143/391 (37%), Gaps = 62/391 (16%) Query 547 LRRCCLPQPGETSN---------LIIMRGARASPRTLNLSQLSFH----RVDQKEITQLS 593 RR C + ++ + R P++ + H +D K +T Sbjct 589 WRRPCDGKGSGNAHDEEELYFHFKVPTRRTFLDPQSCGDPLQAVHLFAKELDAKSVTLEK 648 Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIA 652 LG G + G L++ G QEL V + L D Sbjct 649 SLGAGRFGTLCCGCLQLPGR---------------------QELPVAVHTLRDGCSDSQR 687 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 L+F A + Q H+H+ + GV RG ++VTEY+ G LD +LR G + A M Sbjct 688 LSFLAEALTLGQFDHSHIVRLEGVVTRGNPLMIVTEYMNLGALDDFLRHHEGELVAAQLM 747 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 + LASA+ YL VH + R +L++ L K+S G G G R E Sbjct 748 GLLPGLASAMKYLSEMGYVHRGLAARRVLVSSGLL-------CKIS--GFGRGPRDRAEA 798 Query 773 VERIP-------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 V W APE L G S+A D W FG + E+ GE P S + Sbjct 799 VYTTMSGRSPALWAAPETLQFG--HFSSASDVWSFGIVMWEVMAFGERPYWDMSGQDVIK 856 Query 826 FYQRQHRLPEP-SCP-QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 + RLP P +CP QL L +C +P++RP F I L+++ Sbjct 857 AVEDGFRLPPPRNCPSQLHRLMLECWQKDPSERPRFSQIHSILSKMGQEPEPSKCASTTC 916 Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 P FG V + Sbjct 917 LRPPTPLADRAFSTFP-------SFGSVGAW 940 >sp|Q96285|LRK55_ARATH L-type lectin-domain containing receptor kinase V.5 OS=Arabidopsis thaliana OX=3702 GN=LECRK55 PE=1 SV=1 Length=661 Score = 238 bits (608), Expect = 1e-65, Method: Composition-based stats. Identities = 79/304 (26%), Positives = 132/304 (43%), Gaps = 17/304 (6%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 P A + K+ + LG+G FG+V Y T G+ +AVK D Sbjct 320 QYGPHRFAYKELFNATKGFKEKQLLGKGGFGQV----YKGTLPGSDAEIAVKRTSHD-SR 374 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HS 994 Q S + EI + L H ++++ G C + ++L LV +Y+P GSL YL R Sbjct 375 QGMSEFLAEISTIGRLRHPNLVRLLGYCRHK--ENLYLVYDYMPNGSLDKYLNRSENQER 432 Query 995 IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 + Q + + + +LH + IHRD+ NVL+DN+ ++GDFGLAK +G Sbjct 433 LTWEQRFRIIKDVATALLHLHQEWVQVIIHRDIKPANVLIDNEMNARLGDFGLAKLYDQG 492 Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE- 1110 + + G + APE L+ + ++DV++FG+ + E++ + + E Sbjct 493 FDPETSKVAG--TFGYIAPEFLRTGRATTSTDVYAFGLVMLEVVCGRRIIERRAAENEEY 550 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 L+ ++ + E R + V L C AS RP ++ IL Sbjct 551 LVDWILELWENGKIFDAAEESIRQEQNRGQVELVLKLGVLCSHQAASIRPAMSVVMRILN 610 Query 1171 TVHE 1174 V + Sbjct 611 GVSQ 614 Score = 214 bits (546), Expect = 2e-57, Method: Composition-based stats. Identities = 52/258 (20%), Positives = 96/258 (37%), Gaps = 36/258 (14%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 K + LG+G VY+G L G + + +K Sbjct 334 ATKGFKEKQLLGKGGFGQVYKGTL------------------------PGSDAEIAVKRT 369 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 F S + ++ H +L + G C +V +Y+ +G LD +L R Sbjct 370 SHDSRQGMSEFLAEISTIGRLRHPNLVRLLGYCRHKENLYLVYDYMPNGSLDKYLNRSEN 429 Query 705 HVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLA-RLGLAEGTSPFIKLS 758 + W + + + +A+AL +L + ++H ++ N+L+ + G KL Sbjct 430 QERLTWEQRFRIIKDVATALLHLHQEWVQVIIHRDIKPANVLIDNEMNARLGDFGLAKLY 489 Query 759 DPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 D G + ++APE L G +T+ D + FG +LE+ G ++ R Sbjct 490 DQGF---DPETSKVAGTFGYIAPEFLRTGRA--TTSTDVYAFGLVMLEVVC-GRRIIERR 543 Query 819 SPSEKEHFYQRQHRLPEP 836 + +E+ L E Sbjct 544 AAENEEYLVDWILELWEN 561 >sp|Q7X996|CIPK2_ORYSJ CBL-interacting protein kinase 2 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK2 PE=2 SV=1 Length=443 Score = 232 bits (592), Expect = 1e-65, Method: Composition-based stats. Identities = 58/280 (21%), Positives = 115/280 (41%), Gaps = 26/280 (9%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEI 948 + + + LG+G F KV Y N T E VA+K + + + K+EI Sbjct 7 NMLMKKYEMGKLLGQGTFAKV----YHARNTETSESVAIKMIDKEKVLKGGLMDQIKREI 62 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008 +++ + H +I++ + + + V+E+V G L + + R + + QQ+ Sbjct 63 SVMKLVRHPNIVQLYEVMATKTK--IYFVLEHVKGGELFNKVQRGRLKEDAARKYFQQLI 120 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 + + H++ HRDL N+LLD + +K+ DFGL+ + + +P + Sbjct 121 CAVDFCHSRGVYHRDLKPENLLLDENSNLKVSDFGLSALADCKRQDGLLHTTCGTPA-YV 179 Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + + +D+WS GV L+ LL ++ + + Sbjct 180 APEVINRRGYDGAKADIWSCGVILFVLLAGYLPFHD---------------KNLMDMYKK 224 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + E P +V L+ + S R + + ++ Sbjct 225 IGKAE-FKCPSWFNTDVRRLLLRILDPNPSTRISMDKIME 263 Score = 182 bits (462), Expect = 3e-48, Method: Composition-based stats. Identities = 53/293 (18%), Positives = 98/293 (33%), Gaps = 45/293 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 K+ LGQGT VY R+ V +K++D Sbjct 10 MKKYEMGKLLGQGTFAKVYHA------------------------RNTETSESVAIKMID 45 Query 646 PSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 + S+M V H ++ ++ V + V E+V+ G L + + Sbjct 46 KEKVLKGGLMDQIKREISVMKLVRHPNIVQLYEVMATKTKIYFVLEHVKGGELFN--KVQ 103 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 RG + QQL A+ + ++ + H ++ N+LL + +K+SD G+ Sbjct 104 RGRLKEDAARKYFQQLICAVDFCHSRGVYHRDLKPENLLLDE-------NSNLKVSDFGL 156 Query 763 GLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 A + ++APE + D W G L + G P Sbjct 157 SALADCKRQDGLLHTTCGTPAYVAPEVINRRGYD-GAKADIWSCGVIL-FVLLAGYLPFH 214 Query 817 SRSPSEKE-HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 ++ + + + + P + L + L P+ R S I+ + Sbjct 215 DKNLMDMYKKIGKAEFKCPSWFNTDVRRLLLRILDPNPSTRISMDKIMENPWF 267 >sp|Q0WVM4|Y2239_ARATH Probable LRR receptor-like serine/threonine-protein kinase At2g23950 OS=Arabidopsis thaliana OX=3702 GN=At2g23950 PE=1 SV=1 Length=634 Score = 238 bits (606), Expect = 1e-65, Method: Composition-based stats. Identities = 73/274 (27%), Positives = 120/274 (44%), Gaps = 15/274 (5%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + G G +VAVK LK G S ++ E++++ H ++++ Sbjct 305 LGAGGFGNVYRGKF-----GDGTVVAVKRLKDVNGTSGNSQFRTELEMISLAVHRNLLRL 359 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ---H 1018 G C E+ LV Y+ GS+ L + ++ A G+ YLH Q Sbjct 360 IGYCASSSER--LLVYPYMSNGSVASRLKAKPALDWNTRKKIAIGAARGLFYLHEQCDPK 417 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ A N+LLD +GDFGLAK + HE V V APE L + Sbjct 418 IIHRDVKAANILLDEYFEAVVGDFGLAKLL--NHEDSHVTTAVRGTVGHIAPEYLSTGQS 475 Query 1079 YYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 +DV+ FG+ L EL+T + ++ ++ + +++ EL++R Sbjct 476 SEKTDVFGFGILLLELITGMRALEFGKSVSQKGAMLEWVRKLHKEMKVEELVDRELGTTY 535 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 E+ + C + + RP ++ +L+ Sbjct 536 DRIEVGEMLQVALLCTQFLPAHRPKMSEVVQMLE 569 Score = 190 bits (483), Expect = 1e-49, Method: Composition-based stats. Identities = 69/366 (19%), Positives = 113/366 (31%), Gaps = 66/366 (18%) Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 NL +F V + S LG G NVY G+ Sbjct 283 NLRSFTFRELHVATDGFSSKSILGAGGFGNVYRGK------------------------- 317 Query 633 RGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 G V +K L + F ++S H +L + G C E ++V Y+ Sbjct 318 FGDGTVVAVKRLKDVNGTSGNSQFRTELEMISLAVHRNLLRLIGYCASSSERLLVYPYMS 377 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748 +G + L+ + + + +A A L YL + ++H +V NILL A Sbjct 378 NGSVASRLKA-KPALDWNTRKKIAIGAARGLFYLHEQCDPKIIHRDVKAANILLDEYFEA 436 Query 749 EGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 + D G+ + V + +APE L G + S D +GFG Sbjct 437 V-------VGDFGLAKLLNHEDSHVTTAVRGTVGHIAPEYLSTGQS--SEKTDVFGFGIL 487 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS------------------CPQLATLT 845 LLE+ A +S S+K + +L + ++ + Sbjct 488 LLELITGMRALEFGKSVSQKGAMLEWVRKLHKEMKVEELVDRELGTTYDRIEVGEMLQVA 547 Query 846 SQCLTYEPTQRPSFRTILRDL--TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 C + P RP +++ L L A + Sbjct 548 LLCTQFLPAHRPKMSEVVQMLEGDGLAERWAASHDHSHFYHANMSYRTITSTDGNNQTKH 607 Query 904 GEGHFG 909 G G Sbjct 608 LFGSSG 613 >sp|Q9ZRF9|RPK1_ARATH Probable LRR receptor-like serine/threonine-protein kinase RPK1 OS=Arabidopsis thaliana OX=3702 GN=RPK1 PE=1 SV=1 Length=540 Score = 235 bits (599), Expect = 2e-65, Method: Composition-based stats. Identities = 75/287 (26%), Positives = 117/287 (41%), Gaps = 19/287 (7%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 Y +G G FG PTN + AVK L Q + EI L + Sbjct 260 YFSNSNCIGHGGFGSTYKAEVSPTN-----VFAVKRLSVG-RFQGDQQFHAEISALEMVR 313 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMA 1012 H +++ G E + L+ Y+ G+L+D++ S I L A + ++ Sbjct 314 HPNLVMLIGY--HASETEMFLIYNYLSGGNLQDFIKERSKAAIEWKVLHKIALDVARALS 371 Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH Q +HRD+ N+LLDN+ + DFGL+K + G V + A Sbjct 372 YLHEQCSPKVLHRDIKPSNILLDNNYNAYLSDFGLSKLL--GTSQSHVTTGVAGTFGYVA 429 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHC---DSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 PE + +DV+S+G+ L EL++ D S S ++ A ++ + E Sbjct 430 PEYAMTCRVSEKADVYSYGIVLLELISDKRALDPSFSSHENGFNIVSWAHMMLSQGKAKE 489 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + G P EV HL C S RPT + + +LK + Sbjct 490 VFTTGLWETGPPDDLVEVLHLALKCTVDSLSIRPTMKQAVRLLKRIQ 536 Score = 181 bits (459), Expect = 4e-47, Method: Composition-based stats. Identities = 48/243 (20%), Positives = 83/243 (34%), Gaps = 43/243 (18%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 + + +G G + Y+ + +K L Sbjct 261 FSNSNCIGHGGFGSTYKAEVSPTNVF-------------------------AVKRLSVGR 295 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVP 707 F+ S + V H +L + G E ++ Y+ G L +++ R + + Sbjct 296 FQGDQQFHAEISALEMVRHPNLVMLIGYHASETEMFLIYNYLSGGNLQDFIKERSKAAIE 355 Query 708 MAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 +A +A ALSYL + ++H ++ NILL A LSD G+ Sbjct 356 WKVLHKIALDVARALSYLHEQCSPKVLHRDIKPSNILLDNNYNAY-------LSDFGLSK 408 Query 765 GALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + + V ++APE +S D + +G LLE+ D A S S Sbjct 409 LLGTSQSHVTTGVAGTFGYVAPEYAMTC--RVSEKADVYSYGIVLLELISDKRALDPSFS 466 Query 820 PSE 822 E Sbjct 467 SHE 469 >sp|A0A2R6XIK6|PRAF_MARPO RAF-like serine/threonine-protein kinase PRAF OS=Marchantia polymorpha OX=3197 GN=PRAF PE=1 SV=1 Length=1680 Score = 247 bits (631), Expect = 2e-65, Method: Composition-based stats. Identities = 78/294 (27%), Positives = 124/294 (42%), Gaps = 39/294 (13%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-----GPQHR--SGWKQEIDILRTL 954 +LG G FG V + T+ VA+K +KA C Q R + +E L L Sbjct 1394 ELGSGTFGTVYHGKWRGTD------VAIKRIKASCFAGRPSEQERLIEDFWREACNLGHL 1447 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMA 1012 +H +++ + G D +L V EY+ GSL+ L + +I + LL A GM Sbjct 1448 HHPNVVAFYGVVADGPGGTLATVTEYMVNGSLKQVLQKKDRTIDRRKRLLIAMDAAFGME 1507 Query 1013 YLHAQHYIHRDLAARNVLLD----NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 YLH ++ +H DL N+L++ + + K+GD GL+K V + W Sbjct 1508 YLHGKNIVHFDLKCENLLVNMRDPHRPICKVGDLGLSKV----KHQTMVSGGVRGTLPWM 1563 Query 1069 APECLKEYK--FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 APE L DV+SFG+ ++ELLT + + + Sbjct 1564 APELLNGNSSLVTEKVDVFSFGIVMWELLTGEEPYDKMHYGAI--------------IGG 1609 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180 ++ R P C LM+ CW E + RP+F ++ L+T+ Q + Sbjct 1610 IVNNTLRPLIPSWCDPAWRSLMERCWANEPAVRPSFSDIAKELRTMAAALQPKT 1663 Score = 230 bits (586), Expect = 5e-60, Method: Composition-based stats. Identities = 67/328 (20%), Positives = 121/328 (37%), Gaps = 46/328 (14%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 + ++ +L LG GT VY G+ R V Sbjct 1381 LQTIKNADLEELRELGSGTFGTVYHGKWRGTD--------------------------VA 1414 Query 641 LKVLDPS--------HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM--VTEYV 690 +K + S + F+ A + + H ++ +GV GP + VTEY+ Sbjct 1415 IKRIKASCFAGRPSEQERLIEDFWREACNLGHLHHPNVVAFYGVVADGPGGTLATVTEYM 1474 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 +G L L+++ + ++++A A + YL KN+VH ++ N+L+ + + Sbjct 1475 VNGSLKQVLQKKDRTIDRRKRLLIAMDAAFGMEYLHGKNIVHFDLKCENLLV---NMRDP 1531 Query 751 TSPFIKLSDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 P K+ D G+ + +PW+APE L G ++ ++ +D + FG + E+ Sbjct 1532 HRPICKVGDLGLSKVKHQTMVSGGVRGTLPWMAPELLNGNSSLVTEKVDVFSFGIVMWEL 1591 Query 808 CFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 GE P + +P P +L +C EP RPSF I + Sbjct 1592 L-TGEEPYDKMHYGAIIGGIVNNTLRPLIPSWCDPAWRSLMERCWANEPAVRPSFSDIAK 1650 Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVF 892 +L + P + Sbjct 1651 ELRTMAAALQPKTQAQTQGQSHPHPQMQ 1678 >sp|Q8H1G6|PTI11_ARATH PTI1-like tyrosine-protein kinase 1 OS=Arabidopsis thaliana OX=3702 GN=PTI11 PE=1 SV=1 Length=361 Score = 229 bits (584), Expect = 2e-65, Method: Composition-based stats. Identities = 71/286 (25%), Positives = 121/286 (42%), Gaps = 22/286 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG +G+V G VA+K L + + + ++ ++ L HE++I+ Sbjct 74 IGEGSYGRVYYATL-----NDGVAVALKKLDVAPEAETDTEFLSQVSMVSRLKHENLIQL 128 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------IGLAQLLLFAQQICEGMA 1012 G C D + L E+ +GSL D L + + A + G+ Sbjct 129 LGFCVDGNLR--VLAYEFATMGSLHDILHGRKGVQGAQPGPTLDWITRVKIAVEAARGLE 186 Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH + IHRD+ + NVLL D KI DF L+ P+ ++A Sbjct 187 YLHEKSQPPVIHRDIRSSNVLLFEDYKAKIADFNLSNQAPDNAARLH-STRVLGTFGYHA 245 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE + SDV+SFGV L ELLT + P L+ A +++ ++ + + Sbjct 246 PEYAMTGQLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRLSEDKVKQCI 305 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + + P K ++ + C + EA FRP ++ L+ + + Sbjct 306 DPKLKADYPPKAVAKLAAVAALCVQYEAEFRPNMSIVVKALQPLLK 351 Score = 195 bits (496), Expect = 1e-53, Method: Composition-based stats. Identities = 54/283 (19%), Positives = 97/283 (34%), Gaps = 54/283 (19%) Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 + + LS V + + +G+G+ VY L Sbjct 50 PIEVPPLSLDEVKEKTENFGSKALIGEGSYGRVYYATLNDG------------------- 90 Query 631 RDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 + V LK LD + + F S++S++ H +L + G CV G ++ E+ Sbjct 91 ------VAVALKKLDVAPEAETDTEFLSQVSMVSRLKHENLIQLLGFCVDGNLRVLAYEF 144 Query 690 VEHGPLDVWLRRERG--------HVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGR 738 G L L +G + ++ +A + A L YL K+ ++H ++ Sbjct 145 ATMGSLHDILHGRKGVQGAQPGPTLDWITRVKIAVEAARGLEYLHEKSQPPVIHRDIRSS 204 Query 739 NILLARLGLAEGTSPFIKLSDPGVG------LGALSREERVERIPWLAPECLPGGANSLS 792 N+LL K++D + L + + APE G L+ Sbjct 205 NVLLFE-------DYKAKIADFNLSNQAPDNAARLHSTRVLGTFGYHAPEYAMTG--QLT 255 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 D + FG LLE+ + + ++ RL E Sbjct 256 QKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRLSE 298 >sp|Q9FJ54|CIPKK_ARATH CBL-interacting serine/threonine-protein kinase 20 OS=Arabidopsis thaliana OX=3702 GN=CIPK20 PE=1 SV=1 Length=439 Score = 232 bits (591), Expect = 2e-65, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 113/268 (42%), Gaps = 26/268 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960 LG+G F KV Y N TGE VA+K + + K+EI ++R + H H++ Sbjct 18 LGQGTFAKV----YHARNIKTGESVAIKVIDKQKVAKVGLIDQIKREISVMRLVRHPHVV 73 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + + + MEYV G L D + + + + QQ+ + Y H++ Sbjct 74 FLHEVMASKTK--IYFAMEYVKGGELFDKVSKGKLKENIARKYFQQLIGAIDYCHSRGVY 131 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 HRDL N+LLD + +KI DFGL+ + + +P + APE + + + Sbjct 132 HRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPA-YVAPEVIGKKGYDG 190 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +DVWS GV LY LL + ++ + + +GE P+ Sbjct 191 AKADVWSCGVVLYVLLAGFLPFH---------------EQNLVEMYRKITKGE-FKCPNW 234 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 P EV L+ + + R E ++ Sbjct 235 FPPEVKKLLSRILDPNPNSRIKIEKIME 262 Score = 187 bits (475), Expect = 4e-50, Method: Composition-based stats. Identities = 61/312 (20%), Positives = 102/312 (33%), Gaps = 45/312 (14%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V ++ LGQGT VY R G V +KV Sbjct 7 VLMRKYELGRLLGQGTFAKVYHARNIKTGES------------------------VAIKV 42 Query 644 LDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 +D + + S+M V H H+ F+H V + EYV+ G L + Sbjct 43 IDKQKVAKVGLIDQIKREISVMRLVRHPHVVFLHEVMASKTKIYFAMEYVKGGELFD--K 100 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 +G + QQL A+ Y ++ + H ++ N+LL G +K+SD Sbjct 101 VSKGKLKENIARKYFQQLIGAIDYCHSRGVYHRDLKPENLLLDENGD-------LKISDF 153 Query 761 GVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ S++ ++APE + D W G L + G P Sbjct 154 GLSALRESKQQDGLLHTTCGTPAYVAPEVIGKKGYD-GAKADVWSCGVVLY-VLLAGFLP 211 Query 815 LQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 ++ E + + P P++ L S+ L P R I+ + + Sbjct 212 FHEQNLVEMYRKITKGEFKCPNWFPPEVKKLLSRILDPNPNSRIKIEKIMENSWFQKGFK 271 Query 874 LADVLTVNPDSP 885 + Sbjct 272 KIETPKSPESHQ 283 >sp|Q9FN94|RLK0_ARATH Receptor-like protein kinase At5g59670 OS=Arabidopsis thaliana OX=3702 GN=At5g59670 PE=1 SV=1 Length=868 Score = 242 bits (618), Expect = 2e-65, Method: Composition-based stats. Identities = 80/320 (25%), Positives = 132/320 (41%), Gaps = 17/320 (5%) Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918 TI++ L ++ DV N S + + R LG+G FG V Sbjct 526 MSTIVKGLRLPPRTSMVDVTFSNKKSKRFTYSEVVQVTKNFQRVLGKGGFGMVYHGTVKG 585 Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978 + E VAVK L Q +K E+D+L ++H +++ G C + L LV Sbjct 586 S-----EQVAVKVLSQSST-QGSKEFKAEVDLLLRVHHTNLVSLVGYCCEGD--YLALVY 637 Query 979 EYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLL 1031 E++P G L+ +L I + L A + G+ YLH +HRD+ N+LL Sbjct 638 EFLPNGDLKQHLSGKGGNSIINWSIRLRIALEAALGLEYLHIGCTPPMVHRDVKTANILL 697 Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091 D + K+ DFGL+++ +G + + + PEC + SDV+SFG+ L Sbjct 698 DENFKAKLADFGLSRSF-QGEGESQESTTIAGTLGYLDPECYHSGRLGEKSDVYSFGIVL 756 Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 E++T+ + + QM + E+++ R L +C Sbjct 757 LEMITNQPVINQT-SGDSHITQWVGFQMNRGDILEIMDPNLRKDYNINSAWRALELAMSC 815 Query 1152 WETEASFRPTFENLIPILKT 1171 +S RP+ +I LK Sbjct 816 AYPSSSKRPSMSQVIHELKE 835 Score = 218 bits (555), Expect = 2e-57, Method: Composition-based stats. Identities = 76/345 (22%), Positives = 122/345 (35%), Gaps = 69/345 (20%) Query 563 IMRGARASPRT----LNLSQLSFHRVDQKEITQL-----SHLGQGTRTNVYEGRLRVEGS 613 I++G R PRT + S R E+ Q+ LG+G VY G ++ Sbjct 529 IVKGLRLPPRTSMVDVTFSNKKSKRFTYSEVVQVTKNFQRVLGKGGFGMVYHGTVKGSE- 587 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 +V +KVL S + F L+ +V HT+L + Sbjct 588 ------------------------QVAVKVLSQSSTQGSKEFKAEVDLLLRVHHTNLVSL 623 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NK 728 G C G +V E++ +G L L + G+ + W ++ +A + A L YL Sbjct 624 VGYCCEGDYLALVYEFLPNGDLKQHLSGKGGNSIINWSIRLRIALEAALGLEYLHIGCTP 683 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPE 782 +VH +V NILL + KL+D G+ + + +L PE Sbjct 684 PMVHRDVKTANILLDE-------NFKAKLADFGLSRSFQGEGESQESTTIAGTLGYLDPE 736 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ---SRSPSEKEHFYQRQHRLPEPSCP 839 C G L D + FG LLE+ + Q ++ F + + E P Sbjct 737 CYHSG--RLGEKSDVYSFGIVLLEMITNQPVINQTSGDSHITQWVGFQMNRGDILEIMDP 794 Query 840 QLA------------TLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 L L C ++RPS ++ +L Sbjct 795 NLRKDYNINSAWRALELAMSCAYPSSSKRPSMSQVIHELKECIAC 839 >sp|Q9SA72|Y1357_ARATH Probable receptor-like protein kinase At1g30570 OS=Arabidopsis thaliana OX=3702 GN=At1g30570 PE=3 SV=1 Length=849 Score = 242 bits (617), Expect = 2e-65, Method: Composition-based stats. Identities = 72/283 (25%), Positives = 122/283 (43%), Gaps = 16/283 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FGKV + G ++A+K Q + ++ EI +L L H H++ Sbjct 526 IGVGGFGKVYRGELE-----DGTLIAIKR-ATPHSQQGLAEFETEIVMLSRLRHRHLVSL 579 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLH---A 1016 G C++ E + LV EY+ G+LR +L + Q L G+ YLH Sbjct 580 IGFCDEHNE--MILVYEYMANGTLRSHLFGSNLPPLSWKQRLEACIGSARGLHYLHTGSE 637 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + IHRD+ N+LLD + + K+ DFGL+KA P ++ V + PE + Sbjct 638 RGIIHRDVKTTNILLDENFVAKMSDFGLSKAGP-SMDHTHVSTAVKGSFGYLDPEYFRRQ 696 Query 1077 KFYYASDVWSFGVTLYE-LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + SDV+SFGV L+E + + + P + L A L +++ R Sbjct 697 QLTEKSDVYSFGVVLFEAVCARAVINPTLPKDQINLAEWALSWQKQRNLESIIDSNLRGN 756 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 + + + + C E RP ++ L+ V + ++ Sbjct 757 YSPESLEKYGEIAEKCLADEGKNRPMMGEVLWSLEYVLQIHEA 799 Score = 209 bits (531), Expect = 2e-54, Method: Composition-based stats. Identities = 63/322 (20%), Positives = 98/322 (30%), Gaps = 61/322 (19%) Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 L+ R K +G G VY G L Sbjct 510 LAEIRAATKNFDDGLAIGVGGFGKVYRGELEDG-------------------------TL 544 Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 + +K P F ++S++ H HL + G C E I+V EY+ +G L Sbjct 545 IAIKRATPHSQQGLAEFETEIVMLSRLRHRHLVSLIGFCDEHNEMILVYEYMANGTLRSH 604 Query 699 LRRER-GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPF 754 L + ++ A L YL + ++H +V NILL + Sbjct 605 LFGSNLPPLSWKQRLEACIGSARGLHYLHTGSERGIIHRDVKTTNILLDE-------NFV 657 Query 755 IKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 K+SD G+ S + +L PE L+ D + FG L E Sbjct 658 AKMSDFGLSKAGPSMDHTHVSTAVKGSFGYLDPEYFR--RQQLTEKSDVYSFGVVLFEAV 715 Query 809 FDGEA-----PLQSRSPSEKEHFYQRQHRLPEPSCPQLA------------TLTSQCLTY 851 P + +E +Q+Q L L + +CL Sbjct 716 CARAVINPTLPKDQINLAEWALSWQKQRNLESIIDSNLRGNYSPESLEKYGEIAEKCLAD 775 Query 852 EPTQRPSFRTILRDLTRLQPHN 873 E RP +L L + + Sbjct 776 EGKNRPMMGEVLWSLEYVLQIH 797 >sp|Q9P289|STK26_HUMAN Serine/threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 Length=416 Score = 231 bits (589), Expect = 2e-65, Method: Composition-based stats. Identities = 72/294 (24%), Positives = 123/294 (42%), Gaps = 24/294 (8%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK 933 +A + + K+ +G+G FG+V + ++ T ++VA+K + Sbjct 1 MAHSPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEV----FKGIDNRTQQVVAIKIID 56 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993 + +QEI +L ++ KY G + L ++MEY+ GS D L Sbjct 57 LEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSK--LWIIMEYLGGGSALDLLRAG 114 Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 Q+ ++I +G+ YLH++ IHRD+ A NVLL VK+ DFG+A + + Sbjct 115 PFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD--- 171 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 R FW APE +++ + +D+WS G+T EL + PP Sbjct 172 TQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIEL-----AKGEPP-------- 218 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 M +R+ L+ + + C + SFRPT + L+ Sbjct 219 --NSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLK 270 Score = 209 bits (532), Expect = 6e-58, Method: Composition-based stats. Identities = 61/310 (20%), Positives = 119/310 (38%), Gaps = 44/310 (14%) Query 570 SPRTLNLSQLSFHRVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 SP + + + + D +E T+L +G+G+ V++G Sbjct 4 SPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGI--------------------- 42 Query 629 PGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 D + V +K++D D + +++SQ +++ +G ++G + ++ Sbjct 43 ---DNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIM 99 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 EY+ G LR G + +++ L YL ++ +H ++ N+LL+ G Sbjct 100 EYLGGGSALDLLRA--GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGD 157 Query 748 AEGTSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +KL+D GV + R V W+APE + A + D W G T Sbjct 158 -------VKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSA--YDSKADIWSLGIT 208 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861 +E+ GE P P + + L CL +P+ RP+ + Sbjct 209 AIELA-KGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKE 267 Query 862 ILRDLTRLQP 871 +L+ ++ Sbjct 268 LLKHKFIVKN 277 >sp|F4IB81|LYK3_ARATH LysM domain receptor-like kinase 3 OS=Arabidopsis thaliana OX=3702 GN=LYK3 PE=2 SV=1 Length=651 Score = 238 bits (606), Expect = 2e-65, Method: Composition-based stats. Identities = 72/292 (25%), Positives = 122/292 (42%), Gaps = 34/292 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G++G V + VAVK + A + E+ +L ++H ++++ Sbjct 347 LGHGNYGSVYFGLLRE------QEVAVKRMTATKT----KEFAAEMKVLCKVHHSNLVEL 396 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP------RHSIGLAQLLLFAQQICEGMAYLHA 1016 G E L +V EYV G L+ +L + A G+ Y+H Sbjct 397 IGYAATVDE--LFVVYEYVRKGMLKSHLHDPQSKGNTPLSWIMRNQIALDAARGLEYIHE 454 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 HY+HRD+ N+LLD KI DFGLAK V + E + APE L Sbjct 455 HTKTHYVHRDIKTSNILLDEAFRAKISDFGLAKLVEKTGEGEISVTKVVGTYGYLAPEYL 514 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDS--------SQSPPTKFLELIGIA-----QGQMT 1120 + SD+++FGV L+E+++ ++ +++P + L I +A M Sbjct 515 SDGLATSKSDIYAFGVVLFEIISGREAVIRTEAIGTKNPERRPLASIMLAVLKNSPDSMN 574 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + L E ++ P C ++ L K C + + RP + ++ L + Sbjct 575 MSSLKEFVDPNMMDLYPHDCLFKIATLAKQCVDDDPILRPNMKQVVISLSQI 626 Score = 206 bits (523), Expect = 2e-54, Method: Composition-based stats. Identities = 76/330 (23%), Positives = 118/330 (36%), Gaps = 81/330 (25%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 R E + + LG G +VY G LR E V +K Sbjct 335 RAATDEFSDSNLLGHGNYGSVYFGLLR--------------------------EQEVAVK 368 Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 + + F ++ +V H++L + G E +V EYV G L L Sbjct 369 RMTATKT---KEFAAEMKVLCKVHHSNLVELIGYAATVDELFVVYEYVRKGMLKSHLHDP 425 Query 703 --RGHVPMAWKMV--VAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFI 755 +G+ P++W M +A A L Y+ + VH ++ NILL A Sbjct 426 QSKGNTPLSWIMRNQIALDAARGLEYIHEHTKTHYVHRDIKTSNILLDEAFRA------- 478 Query 756 KLSDPGVGL-------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 K+SD G+ G +S + V +LAPE L G ++ D + FG L EI Sbjct 479 KISDFGLAKLVEKTGEGEISVTKVVGTYGYLAPEYLSDGLA--TSKSDIYAFGVVLFEII 536 Query 809 FDGE----------------------------APLQSRSPSEKEHFYQRQHRLPEPSC-P 839 E +P S KE L C Sbjct 537 SGREAVIRTEAIGTKNPERRPLASIMLAVLKNSPDSMNMSSLKEFVDPNMMDLYPHDCLF 596 Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 ++ATL QC+ +P RP+ + ++ L+++ Sbjct 597 KIATLAKQCVDDDPILRPNMKQVVISLSQI 626 >sp|O04534|LRK51_ARATH Putative L-type lectin-domain containing receptor kinase V.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK51 PE=3 SV=1 Length=666 Score = 238 bits (607), Expect = 2e-65, Method: Composition-based stats. Identities = 73/279 (26%), Positives = 122/279 (44%), Gaps = 16/279 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FGKV Y T + +AVK + D Q + EI + L H ++++ Sbjct 350 LGKGGFGKV----YKGTLPVSNVEIAVKMVSHD-SRQGMREFIAEIATIGRLRHPNLVRL 404 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018 +G C +GE L LV + + GSL +L ++ +Q + + G+ YLH Q Sbjct 405 QGYCRHKGE--LYLVYDCMAKGSLDKFLYHQQTGNLDWSQRFKIIKDVASGLYYLHQQWV 462 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ N+LLD + K+GDFGLAK G + G + + +PE + Sbjct 463 QVIIHRDIKPANILLDANMNAKLGDFGLAKLCDHGTDPQTSHVAG--TLGYISPELSRTG 520 Query 1077 KFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 K SDV++FG+ + E+ + + L + ++L+ Sbjct 521 KASTRSDVFAFGIVMLEIACGRKPILPRASQREMVLTDWVLECWENEDIMQVLDHKIGQE 580 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 ++ V L C A+ RP ++I +L +V + Sbjct 581 YVEEQAALVLKLGLFCSHPVAAIRPNMSSVIQLLDSVAQ 619 Score = 219 bits (558), Expect = 5e-59, Method: Composition-based stats. Identities = 51/272 (19%), Positives = 95/272 (35%), Gaps = 43/272 (16%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 + + K LG+G VY+G L V Sbjct 329 PHRFAFKDLHIATKGFKDTEVLGKGGFGKVYKGTLPVSN--------------------- 367 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + + +K++ F + + ++ H +L + G C E +V + + G Sbjct 368 ---VEIAVKMVSHDSRQGMREFIAEIATIGRLRHPNLVRLQGYCRHKGELYLVYDCMAKG 424 Query 694 PLDVWL-RRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAE 749 LD +L ++ G++ + + + + +AS L YL + ++H ++ NILL Sbjct 425 SLDKFLYHQQTGNLDWSQRFKIIKDVASGLYYLHQQWVQVIIHRDIKPANILLD------ 478 Query 750 GTSPFIKLSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 + KL D G+ + +++PE G ST D + FG + Sbjct 479 -ANMNAKLGDFGLAKLCDHGTDPQTSHVAGTLGYISPELSRTGKA--STRSDVFAFGIVM 535 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836 LEI G P+ R+ + E Sbjct 536 LEIAC-GRKPILPRASQREMVLTDWVLECWEN 566 >sp|O22932|CIPKB_ARATH CBL-interacting serine/threonine-protein kinase 11 OS=Arabidopsis thaliana OX=3702 GN=CIPK11 PE=1 SV=1 Length=435 Score = 231 bits (590), Expect = 2e-65, Method: Composition-based stats. Identities = 65/270 (24%), Positives = 112/270 (41%), Gaps = 28/270 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC---GPQHRSGWKQEIDILRTLYHEHI 959 LG G F KV + + TG+ VAVK L P + K+EI I+R L H +I Sbjct 27 LGCGAFAKV----FHARDRRTGQSVAVKILNKKKLLTNPALANNIKREISIMRRLSHPNI 82 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018 +K + + + ME+V G L + + +H + + QQ+ + Y HA+ Sbjct 83 VKLHEVMATKSK--IFFAMEFVKGGELFNKISKHGRLSEDLSRRYFQQLISAVGYCHARG 140 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N+L+D + +K+ DFGL+ + + +P + APE L + + Sbjct 141 VYHRDLKPENLLIDENGNLKVSDFGLSALTDQIRPDGLLHTLCGTPA-YVAPEILSKKGY 199 Query 1079 -YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 DVWS G+ L+ L+ P V+ + + + +GE P Sbjct 200 EGAKVDVWSCGIVLFVLVAGYLPFNDP---------------NVMNMYKKIYKGEYR-FP 243 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 ++ + + R T + ++ Sbjct 244 RWMSPDLKRFVSRLLDINPETRITIDEILK 273 Score = 182 bits (463), Expect = 1e-48, Method: Composition-based stats. Identities = 63/373 (17%), Positives = 116/373 (31%), Gaps = 51/373 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP- 646 + LG G V+ RDR V +K+L+ Sbjct 20 KYELGKLLGCGAFAKVFHA------------------------RDRRTGQSVAVKILNKK 55 Query 647 ---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 ++ +A S+M ++SH ++ +H V + E+V+ G L + + Sbjct 56 KLLTNPALANNIKREISIMRRLSHPNIVKLHEVMATKSKIFFAMEFVKGGELFNKISKH- 114 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 G + QQL SA+ Y + + H ++ N+L+ G +K+SD G+ Sbjct 115 GRLSEDLSRRYFQQLISAVGYCHARGVYHRDLKPENLLIDENG-------NLKVSDFGLS 167 Query 764 LGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 ++APE L +D W G L + G P Sbjct 168 ALTDQIRPDGLLHTLCGTPAYVAPEILSKKGYE-GAKVDVWSCGIVL-FVLVAGYLPFND 225 Query 818 RSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 + + +R P P L S+ L P R + IL+D ++ Sbjct 226 PNVMNMYKKIYKGEYRFPRWMSPDLKRFVSRLLDINPETRITIDEILKDPWFVRGGFKQI 285 Query 877 VLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC 936 + + DL G + ++ +GE + Sbjct 286 KFHDDEIEDQKVESSLEAVKSLNAFDLISYSSGLDLSGLFAGCSNSSGES------ERFL 339 Query 937 GPQHRSGWKQEID 949 + +E++ Sbjct 340 SEKSPEMLAEEVE 352 >sp|Q9FHG4|LRKS7_ARATH Probable L-type lectin-domain containing receptor kinase S.7 OS=Arabidopsis thaliana OX=3702 GN=LECRKS7 PE=2 SV=1 Length=681 Score = 238 bits (607), Expect = 2e-65, Method: Composition-based stats. Identities = 66/286 (23%), Positives = 128/286 (45%), Gaps = 20/286 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 R +G G FG V + +G + AVK + + + ++ + E+ I+ L H Sbjct 365 FHSSRVIGRGAFGNVYRAMF----VSSGTISAVKRSRHNST-EGKTEFLAELSIIACLRH 419 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEG 1010 +++++ +G C ++GE L LV E++P GSL L + S + + L A + Sbjct 420 KNLVQLQGWCNEKGE--LLLVYEFMPNGSLDKILYQESQTGAVALDWSHRLNIAIGLASA 477 Query 1011 MAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 ++YLH Q +HRD+ N++LD + ++GDFGLA+ G + + Sbjct 478 LSYLHHECEQQVVHRDIKTSNIMLDINFNARLGDFGLARLTEHDKSPVSTLTAG--TMGY 535 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT--KFLELIGIAQGQMTVLRLT 1125 APE L+ +D +S+GV + E+ P K + L+ + R+ Sbjct 536 LAPEYLQYGTATEKTDAFSYGVVILEVACGRRPIDKEPESQKTVNLVDWVWRLHSEGRVL 595 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 E ++ + ++ ++ + C +++ RP+ ++ IL Sbjct 596 EAVDERLKGEFDEEMMKKLLLVGLKCAHPDSNERPSMRRVLQILNN 641 Score = 206 bits (524), Expect = 2e-54, Method: Composition-based stats. Identities = 63/344 (18%), Positives = 118/344 (34%), Gaps = 65/344 (19%) Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + S+ + K +G+G NVY G+ Sbjct 349 GLREFSYKELYTATKGFHSSRVIGRGAFGNVYRAMFVSSGTIS----------------- 391 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 +K + + F S+++ + H +L + G C E ++V E++ + Sbjct 392 -------AVKRSRHNSTEGKTEFLAELSIIACLRHKNLVQLQGWCNEKGELLLVYEFMPN 444 Query 693 GPLDVWLRRERGH----VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARL 745 G LD L +E + + ++ +A LASALSYL + +VH ++ NI+L Sbjct 445 GSLDKILYQESQTGAVALDWSHRLNIAIGLASALSYLHHECEQQVVHRDIKTSNIMLD-- 502 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800 + +L D G+ + V + +LAPE L G + + D + + Sbjct 503 -----INFNARLGDFGLARLTEHDKSPVSTLTAGTMGYLAPEYLQYG--TATEKTDAFSY 555 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP------------------EPSCPQLA 842 G +LE+ + + + RL E +L Sbjct 556 GVVILEVACGRRPIDKEPESQKTVNLVDWVWRLHSEGRVLEAVDERLKGEFDEEMMKKLL 615 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 + +C + +RPS R +L+ L + + Sbjct 616 LVGLKCAHPDSNERPSMRRVLQILNNEIEPSPVPKMKPTLSFSC 659 >sp|Q8VYY5|NCRK_ARATH Receptor-like serine/threonine-protein kinase NCRK OS=Arabidopsis thaliana OX=3702 GN=NCRK PE=1 SV=1 Length=565 Score = 235 bits (600), Expect = 2e-65, Method: Composition-based stats. Identities = 74/326 (23%), Positives = 120/326 (37%), Gaps = 20/326 (6%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 L + + + + +G G V Sbjct 175 CFFQNASLFCVSKPETIHGAIFQFSYTELEQATNKFSSNSVIGHGGSSCVYRGQLK---- 230 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL--QLVME 979 G+ A+K L G + + E+++L L+H H++ G C + K LV E Sbjct 231 -DGKTAAIKRLNTPKGDDTDTLFSTEVELLSRLHHYHVVPLIGYCSEFHGKHAERLLVFE 289 Query 980 YVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDN 1033 Y+ GSLRD L + + A G+ YLH +HRD+ + N+LLD Sbjct 290 YMSYGSLRDCLDGELGEKMTWNIRISVALGAARGLEYLHEAAAPRILHRDVKSTNILLDE 349 Query 1034 DRLVKIGDFGLAKAVPEG---HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 + KI D G+AK + ++APE SDV+SFGV Sbjct 350 NWHAKITDLGMAKCLSSDGLQSGSSSPTTGLQGTFGYFAPEYAIAGCASQMSDVFSFGVV 409 Query 1091 LYELLTHCDSSQSPP----TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 L EL+T Q P + L + + + Q + + EL + ++ + + Sbjct 410 LLELITGRKPIQKPSNNKGEESLVIWAVPRLQDSKRVIEELPDPRLNGKFAEEEMQIMAY 469 Query 1147 LMKNCWETEASFRPTFENLIPILKTV 1172 L K C + RPT ++ IL T+ Sbjct 470 LAKECLLLDPESRPTMREVVQILSTI 495 Score = 195 bits (495), Expect = 2e-51, Method: Composition-based stats. Identities = 69/366 (19%), Positives = 121/366 (33%), Gaps = 77/366 (21%) Query 567 ARASPRTLNLSQLSFHRVD----QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 + P T++ + F + + + S +G G + VY G+L+ + Sbjct 184 CVSKPETIHGAIFQFSYTELEQATNKFSSNSVIGHGGSSCVYRGQLKDGKTA-------- 235 Query 623 DEDPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-- 679 +K L+ P D F L+S++ H H+ + G C Sbjct 236 -----------------AIKRLNTPKGDDTDTLFSTEVELLSRLHHYHVVPLIGYCSEFH 278 Query 680 --GPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHG 733 E ++V EY+ +G L L E G + ++ VA A L YL ++H Sbjct 279 GKHAERLLVFEYMSYGSLRDCLDGELGEKMTWNIRISVALGAARGLEYLHEAAAPRILHR 338 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR----------EERVERIPWLAPEC 783 +V NILL + K++D G+ S + APE Sbjct 339 DVKSTNILLDE-------NWHAKITDLGMAKCLSSDGLQSGSSSPTTGLQGTFGYFAPEY 391 Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-------------- 829 G S D + FG LLE+ + + + +E Sbjct 392 AIAGCA--SQMSDVFSFGVVLLELITGRKPIQKPSNNKGEESLVIWAVPRLQDSKRVIEE 449 Query 830 ------QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 + E +A L +CL +P RP+ R +++ L+ + P + + Sbjct 450 LPDPRLNGKFAEEEMQIMAYLAKECLLLDPESRPTMREVVQILSTITPDTSSRRRNFPIN 509 Query 884 SPASDP 889 Sbjct 510 YLFQSN 515 >sp|Q64725|KSYK_RAT Tyrosine-protein kinase SYK OS=Rattus norvegicus OX=10116 GN=Syk PE=1 SV=1 Length=629 Score = 237 bits (604), Expect = 2e-65, Method: Composition-based stats. Identities = 100/325 (31%), Positives = 147/325 (45%), Gaps = 23/325 (7%) Query 851 YEPTQRPS--FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 YEPT R + R+ + + + + K + +LG G+F Sbjct 317 YEPTGGAWGPDRGLQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDNELGSGNF 376 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 G V Y V + LK + P + E ++++ L + +I++ G CE Sbjct 377 GTVKKGYYQMKKVVKTVAVKI--LKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICE 434 Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 +S LVME G L YL ++ I ++ Q+ GM YL +++HRDLAA Sbjct 435 ---AESWMLVMEMAAWGPLNKYLQQNRHIKDKNIIELVHQVSMGMKYLEESNFVHRDLAA 491 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RNVLL KI DFGL+KA+ YY+ + G PV WYAPEC+ +KF SDVWS Sbjct 492 RNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYFKFSSKSDVWS 551 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 FGV ++E ++ M +T +LE+GER+ P CP E+Y Sbjct 552 FGVLMWEAFSYGQK--------------PYRGMKGSEVTAMLEKGERMGCPPGCPREMYD 597 Query 1147 LMKNCWETEASFRPTFENLIPILKT 1171 LM CW + RP F + L+ Sbjct 598 LMFLCWTYDVENRPGFAAVELRLRN 622 Score = 206 bits (524), Expect = 8e-55, Method: Composition-based stats. Identities = 64/290 (22%), Positives = 113/290 (39%), Gaps = 40/290 (14%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + + LG G V +G +++ K+ + P LK Sbjct 367 EDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDP----------ALK-------- 408 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 A++M Q+ + ++ + G+C ++V E GPL+ +L++ R H+ Sbjct 409 --DELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAAWGPLNKYLQQNR-HIKDKN 464 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + + Q++ + YLE N VH ++ RN+LL T + K+SD G+ + E Sbjct 465 IIELVHQVSMGMKYLEESNFVHRDLAARNVLL-------VTQHYAKISDFGLSKALRADE 517 Query 771 ERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + + W APEC+ S+ D W FG + E G+ P + SE Sbjct 518 NYYKAQTHGKWPVKWYAPECI--NYFKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEV 575 Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 ++ R+ P ++ L C TY+ RP F + L Sbjct 576 TAMLEKGERMGCPPGCPREMYDLMFLCWTYDVENRPGFAAVELRLRNYYY 625 Score = 35.8 bits (81), Expect = 2.7, Method: Composition-based stats. Identities = 18/87 (21%), Positives = 30/87 (34%), Gaps = 12/87 (14%) Query 453 GPLLEPFVQAKLRP---EDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQ 509 G + + L DGLYL+ S ++ L+VA +A + IE+ Sbjct 17 GNITREEAEDYLVQGGMTDGLYLLRQSRNYLGGFALSVAHNRKA---------HHYTIER 67 Query 510 QDGAFVLEGWGRSFPSVRELGAALQGC 536 + GR+ S +L Sbjct 68 ELNGTYAISGGRAHASPADLCHYHSQE 94 >sp|Q54U31|SHKD_DICDI Dual specificity protein kinase shkD OS=Dictyostelium discoideum OX=44689 GN=shkD PE=3 SV=1 Length=744 Score = 239 bits (611), Expect = 3e-65, Method: Composition-based stats. Identities = 69/277 (25%), Positives = 120/277 (43%), Gaps = 31/277 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG+G FG V G+ VAVK K + ++ E+ I+ ++H +++ Sbjct 282 FLGQGSFGSVYKG------KCRGQEVAVKIPRKQKLSLYELTSFRHEVKIMSKIFHPNVV 335 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHA 1016 + G C G+ +Q+V E L L + L + + A+ GM +LH Sbjct 336 LFLGACTQSGK--MQIVTELCQ-TDLEKLLHNDRTKKEFSLFRRMQMAKDAALGMNWLHG 392 Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +H DL N+L+D + VK+ DFG + + EG E+ + W APE + Sbjct 393 ITRIVHNDLKTANLLVDINLRVKVTDFGFS-QIKEGEEFQD--KAAKGTPLWMAPEVMMG 449 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + +DV+SFG+ L+E+LT ++P + + + + ER P Sbjct 450 NPYNEKADVYSFGIILWEILT----KEAPYSHHKDY---------DIFFNAICNEKERPP 496 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P + HL++ CW+ RP+F ++ L + Sbjct 497 IPADTLPSLRHLIQTCWDHNPQNRPSFSEILFRLNEI 533 Score = 216 bits (550), Expect = 2e-57, Method: Composition-based stats. Identities = 74/386 (19%), Positives = 128/386 (33%), Gaps = 56/386 (15%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + +EI + LGQG+ +VY+G+ R GQE+ V + Sbjct 270 PEILPEEIDRTDFLGQGSFGSVYKGKCR------------------------GQEVAVKI 305 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 +F +MS++ H ++ G C + + +VTE + L+ L Sbjct 306 PRKQKLSLYELTSFRHEVKIMSKIFHPNVVLFLGACTQSGKMQIVTELCQ-TDLEKLLHN 364 Query 702 ER--GHVPMAWKMVVAQQLASALSYLEN-KNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 +R + +M +A+ A +++L +VH ++ N+L+ + +K++ Sbjct 365 DRTKKEFSLFRRMQMAKDAALGMNWLHGITRIVHNDLKTANLLVD-------INLRVKVT 417 Query 759 DPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 D G + W+APE + G N + D + FG L EI EAP Sbjct 418 DFGFSQIKEGEEFQDKAAKGTPLWMAPEVMMG--NPYNEKADVYSFGIILWEILTK-EAP 474 Query 815 LQSRSPSEKEH--FYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + + R +P + P L L C + P RPSF IL L + Sbjct 475 YSHHKDYDIFFNAICNEKERPPIPADTLPSLRHLIQTCWDHNPQNRPSFSEILFRLNEIL 534 Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA-V 929 D + + T+ A + Sbjct 535 IDCAIDFDDGRKYWKEHFLVPKQELQEEVEWSD--------FEKTLKATHKQLNLDYAPL 586 Query 930 KALKADCGPQHRSGWKQEIDILRTLY 955 K L Q KQ + + Sbjct 587 KELLVQQSHQTVQKTKQ-VVTMERFD 611 >sp|Q3SWY6|STK25_BOVIN Serine/threonine-protein kinase 25 OS=Bos taurus OX=9913 GN=STK25 PE=2 SV=1 Length=426 Score = 231 bits (588), Expect = 3e-65, Method: Composition-based stats. Identities = 72/290 (25%), Positives = 123/290 (42%), Gaps = 24/290 (8%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + V + K+ +G+G FG+V Y ++ T E+VA+K + + Sbjct 1 MAHLRGFANQHSRVDPEELFTKLDRIGKGSFGEV----YKGIDNRTKEVVAIKIIDLEEA 56 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL 997 +QEI +L +I +Y G + L ++MEY+ GS D L + Sbjct 57 EDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTK--LWIIMEYLGGGSALDLLKPGPLEE 114 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + ++I +G+ YLH++ IHRD+ A NVLL VK+ DFG+A + + Sbjct 115 TYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD---TQIK 171 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 R FW APE +K+ + + +D+WS G+T EL + PP Sbjct 172 RNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIEL-----AKGEPP----------NS 216 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + +R+ L+ + ++ C + FRPT + L+ Sbjct 217 DLHPMRVLFLIPKNSPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLK 266 Score = 202 bits (513), Expect = 3e-55, Method: Composition-based stats. Identities = 60/297 (20%), Positives = 110/297 (37%), Gaps = 44/297 (15%) Query 583 RVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 RVD +E T+L +G+G+ VY+G D + V + Sbjct 13 RVDPEELFTKLDRIGKGSFGEVYKGI------------------------DNRTKEVVAI 48 Query 642 KVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K++D D + +++SQ ++ G ++ + ++ EY+ G L+ Sbjct 49 KIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLK 108 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G + + + +++ L YL ++ +H ++ N+LL+ G +KL+D Sbjct 109 --PGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGD-------VKLADF 159 Query 761 GVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 GV + R V W+APE + A D W G T +E+ GE P Sbjct 160 GVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDF--KADIWSLGITAIELA-KGEPPNS 216 Query 817 SRSPSEKEHFYQRQ--HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P + L CL +P RP+ + +L+ + Sbjct 217 DLHPMRVLFLIPKNSPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRY 273 >sp|Q9SZD5|LRK59_ARATH L-type lectin-domain containing receptor kinase V.9 OS=Arabidopsis thaliana OX=3702 GN=LECRK59 PE=2 SV=1 Length=669 Score = 238 bits (606), Expect = 3e-65, Method: Composition-based stats. Identities = 82/282 (29%), Positives = 125/282 (44%), Gaps = 20/282 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FGKV Y T + +AVK + D Q + EI + L H ++++ Sbjct 350 LGKGGFGKV----YKGTLSTSNMDIAVKKVSHD-SRQGMREFVAEIATIGRLRHPNLVRL 404 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018 G C +GE L LV + +P GSL +L P S+ +Q + + G+ YLH Q Sbjct 405 LGYCRRKGE--LYLVYDCMPKGSLDKFLYHQPEQSLDWSQRFKIIKDVASGLCYLHHQWV 462 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ NVLLD+ K+GDFGLAK G + + + +PE + Sbjct 463 QVIIHRDIKPANVLLDDSMNGKLGDFGLAKLCEHGFDPQT--SNVAGTFGYISPELSRTG 520 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 K +SDV++FG+ + E+ T P + + + L ER+ + Sbjct 521 KASTSSDVFAFGILMLEI-TCGRRPVLPRASSPSEMVLTDWVLDCWEDDILQVVDERVKQ 579 Query 1137 PDKCPCE----VYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 DK E V L C A+ RP+ ++I L V + Sbjct 580 DDKYLEEQVALVLKLGLFCSHPVAAVRPSMSSVIQFLDGVAQ 621 Score = 218 bits (554), Expect = 2e-58, Method: Composition-based stats. Identities = 55/280 (20%), Positives = 95/280 (34%), Gaps = 61/280 (22%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + K LG+G VY+G L + + +K Sbjct 339 IATKGFRNSELLGKGGFGKVYKGTLSTSN------------------------MDIAVKK 374 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL-RRE 702 + F + + ++ H +L + G C R E +V + + G LD +L + Sbjct 375 VSHDSRQGMREFVAEIATIGRLRHPNLVRLLGYCRRKGELYLVYDCMPKGSLDKFLYHQP 434 Query 703 RGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + + + + + +AS L YL + + ++H ++ N+LL S KL D Sbjct 435 EQSLDWSQRFKIIKDVASGLCYLHHQWVQVIIHRDIKPANVLLD-------DSMNGKLGD 487 Query 760 PGVGLGALS-----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ +++PE G ST+ D + FG +LEI G P Sbjct 488 FGLAKLCEHGFDPQTSNVAGTFGYISPELSRTGKA--STSSDVFAFGILMLEI-TCGRRP 544 Query 815 LQSR--SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYE 852 + R SPSE L C + Sbjct 545 VLPRASSPSEMV----------------LTDWVLDCWEDD 568 >sp|C0LGQ5|GSO1_ARATH LRR receptor-like serine/threonine-protein kinase GSO1 OS=Arabidopsis thaliana OX=3702 GN=GSO1 PE=1 SV=1 Length=1249 Score = 246 bits (627), Expect = 3e-65, Method: Composition-based stats. Identities = 73/315 (23%), Positives = 124/315 (39%), Gaps = 22/315 (7%) Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931 H + + + L + +G G GKV + GE VAVK Sbjct 926 HKPLFRNGASKSDIRWEDIMEATHNLSEEFMIGSGGSGKVYKAELE-----NGETVAVKK 980 Query 932 LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP 991 + + +E+ L + H H++K G C + E L+ EY+ GS+ D+L Sbjct 981 ILWKDDLMSNKSFSREVKTLGRIRHRHLVKLMGYCSSKSEGLNLLIYEYMKNGSIWDWLH 1040 Query 992 RHS---------IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKI 1039 + L A + +G+ YLH +HRD+ + NVLLD++ + Sbjct 1041 EDKPVLEKKKKLLDWEARLRIAVGLAQGVEYLHHDCVPPIVHRDIKSSNVLLDSNMEAHL 1100 Query 1040 GDFGLAKAVPEGHEYYR-VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 GDFGLAK + E + + APE K SDV+S G+ L E++T Sbjct 1101 GDFGLAKVLTENCDTNTDSNTWFACSYGYIAPEYAYSLKATEKSDVYSMGIVLMEIVTGK 1160 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLT--ELLERGERLPRP--DKCPCEVYHLMKNCWET 1154 + S ++++ + + V +L++ + P + C+V + C +T Sbjct 1161 MPTDSVFGAEMDMVRWVETHLEVAGSARDKLIDPKLKPLLPFEEDAACQVLEIALQCTKT 1220 Query 1155 EASFRPTFENLIPIL 1169 RP+ L Sbjct 1221 SPQERPSSRQACDSL 1235 Score = 186 bits (472), Expect = 2e-46, Method: Composition-based stats. Identities = 60/340 (18%), Positives = 116/340 (34%), Gaps = 77/340 (23%) Query 577 SQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 S + + + +++ +G G VY+ L + G Sbjct 937 SDIRWEDIMEATHNLSEEFMIGSGGSGKVYKAEL-----------------------ENG 973 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEH 692 + + V K+L +F + ++ H HL + G C E N+++ EY+++ Sbjct 974 ETVAVK-KILWKDDLMSNKSFSREVKTLGRIRHRHLVKLMGYCSSKSEGLNLLIYEYMKN 1032 Query 693 GPLDVWLR-------RERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILL 742 G + WL +++ + ++ +A LA + YL + +VH ++ N+LL Sbjct 1033 GSIWDWLHEDKPVLEKKKKLLDWEARLRIAVGLAQGVEYLHHDCVPPIVHRDIKSSNVLL 1092 Query 743 ARLGLAEGTSPFIKLSDPGVGL--------GALSREERVERIPWLAPECLPGGANSLSTA 794 ++ L D G+ S ++APE + + Sbjct 1093 D-------SNMEAHLGDFGLAKVLTENCDTNTDSNTWFACSYGYIAPEYA--YSLKATEK 1143 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--------------------- 833 D + G L+EI G+ P S +E + + L Sbjct 1144 SDVYSMGIVLMEIV-TGKMPTDSVFGAEMDMVRWVETHLEVAGSARDKLIDPKLKPLLPF 1202 Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 E + Q+ + QC P +RPS R L + + Sbjct 1203 EEDAACQVLEIALQCTKTSPQERPSSRQACDSLLHVYNNR 1242 >sp|Q1HKZ5|M3K13_MOUSE Mitogen-activated protein kinase kinase kinase 13 OS=Mus musculus OX=10090 GN=Map3k13 PE=1 SV=1 Length=959 Score = 243 bits (620), Expect = 3e-65, Method: Composition-based stats. Identities = 83/301 (28%), Positives = 122/301 (41%), Gaps = 35/301 (12%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + + + + D + +++ LG G G V L + E VA+K Sbjct 141 WNIIGKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRA------EEVAIK 194 Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 ++ I LR L H +II +KG C ++MEY G L + L Sbjct 195 KVREQNETD--------IKHLRKLKHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVL 244 Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 I L+ ++ I GM YLH IHRDL + NVL+ + VKI DFG +K + Sbjct 245 RAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELS 304 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 + + V W APE ++ D+WSFGV L+ELLT P K + Sbjct 305 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG-----EIPYKDV 355 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + I G + LP P CP LMK W+++ RP+F + L Sbjct 356 DSSAIIWGVGSN---------SLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHL 406 Query 1170 K 1170 Sbjct 407 D 407 Score = 216 bits (550), Expect = 2e-56, Method: Composition-based stats. Identities = 65/305 (21%), Positives = 109/305 (36%), Gaps = 50/305 (16%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 +A L Q V +EI++L LG G + V+ G+ R E Sbjct 145 GKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAE--------------- 189 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 V +K + + + ++ H ++ GVC + P ++ Sbjct 190 -----------EVAIKKVREQNE-------TDIKHLRKLKHPNIIAFKGVCTQAPCYCII 231 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 EY HG L LR R + + + +AS ++YL ++H ++ N+L+ Sbjct 232 MEYCAHGQLYEVLRAGR-KITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTD 290 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +K+SD G + ++ + W+APE + +S +D W FG Sbjct 291 A-------VKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 341 Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 L E+ GE P + S +P L Q +P RPSFR Sbjct 342 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFR 400 Query 861 TILRD 865 L Sbjct 401 QTLMH 405 >sp|Q9LDT0|CRK30_ARATH Putative cysteine-rich receptor-like protein kinase 30 OS=Arabidopsis thaliana OX=3702 GN=CRK30 PE=3 SV=1 Length=700 Score = 238 bits (608), Expect = 3e-65, Method: Composition-based stats. Identities = 72/296 (24%), Positives = 112/296 (38%), Gaps = 21/296 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G+G FG+V G VAVK L Q +K E+ ++ L H +++ Sbjct 350 NKIGQGGFGEVYKGTL-----SNGTEVAVKRLSR-TSDQGELEFKNEVLLVAKLQHRNLV 403 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEGMAY 1013 + G QGE+ + LV E+VP SL +L + + + I G+ Y Sbjct 404 RLLG-FALQGEEKI-LVFEFVPNKSLDYFLFGSTNPTKKGQLDWTRRYNIIGGITRGLLY 461 Query 1014 LHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 LH IHRD+ A N+LLD D KI DFG+A+ + H+ + P Sbjct 462 LHQDSRLTIIHRDIKASNILLDADMNPKIADFGMARNFRD-HQTEDSTGRVVGTFGYMPP 520 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 E + +F SDV+SFGV + E+++ S L+ EL+ Sbjct 521 EYVAHGQFSTKSDVYSFGVLILEIVSGRKNSSFYQMDGSVCNLVTYVWRLWNTDSSLELV 580 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 + H+ C + RP + +L P F Sbjct 581 DPAISGSYEKDEVTRCIHIGLLCVQENPVNRPALSTIFQMLTNSSITLNVPQPPGF 636 Score = 229 bits (583), Expect = 5e-62, Method: Composition-based stats. Identities = 59/327 (18%), Positives = 107/327 (33%), Gaps = 68/327 (21%) Query 573 TLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 T+ Q ++ + +GQG VY+G L Sbjct 328 TVGYLQFDIKDIEAATSNFLASNKIGQGGFGEVYKGTLSNG------------------- 368 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 V +K L + L F L++++ H +L + G ++G E I+V E+V Sbjct 369 ------TEVAVKRLSRTSDQGELEFKNEVLLVAKLQHRNLVRLLGFALQGEEKILVFEFV 422 Query 691 EHGPLDVWLRR-----ERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILL 742 + LD +L ++G + + + + L YL + ++H ++ NILL Sbjct 423 PNKSLDYFLFGSTNPTKKGQLDWTRRYNIIGGITRGLLYLHQDSRLTIIHRDIKASNILL 482 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMD 796 K++D G+ + V ++ PE + G ST D Sbjct 483 D-------ADMNPKIADFGMARNFRDHQTEDSTGRVVGTFGYMPPEYVAHG--QFSTKSD 533 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC------------------ 838 + FG +LEI + + + RL Sbjct 534 VYSFGVLILEIVSGRKNSSFYQMDGSVCNLVTYVWRLWNTDSSLELVDPAISGSYEKDEV 593 Query 839 PQLATLTSQCLTYEPTQRPSFRTILRD 865 + + C+ P RP+ TI + Sbjct 594 TRCIHIGLLCVQENPVNRPALSTIFQM 620 >sp|Q9Z2W1|STK25_MOUSE Serine/threonine-protein kinase 25 OS=Mus musculus OX=10090 GN=Stk25 PE=1 SV=2 Length=426 Score = 231 bits (588), Expect = 3e-65, Method: Composition-based stats. Identities = 72/290 (25%), Positives = 123/290 (42%), Gaps = 24/290 (8%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + V + K+ +G+G FG+V Y ++ T E+VA+K + + Sbjct 1 MAHLRGFAHQHSRVDPEELFTKLDRIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEA 56 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL 997 +QEI +L +I +Y G + L ++MEY+ GS D L + Sbjct 57 EDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTK--LWIIMEYLGGGSALDLLKPGPLEE 114 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + ++I +G+ YLH++ IHRD+ A NVLL VK+ DFG+A + + Sbjct 115 TYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD---TQIK 171 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 R FW APE +K+ + + +D+WS G+T EL + PP Sbjct 172 RNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIEL-----AKGEPP----------NS 216 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + +R+ L+ + ++ C + FRPT + L+ Sbjct 217 DLHPMRVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLK 266 Score = 201 bits (511), Expect = 5e-55, Method: Composition-based stats. Identities = 60/297 (20%), Positives = 111/297 (37%), Gaps = 44/297 (15%) Query 583 RVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 RVD +E T+L +G+G+ VY+G D + V + Sbjct 13 RVDPEELFTKLDRIGKGSFGEVYKGI------------------------DNHTKEVVAI 48 Query 642 KVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K++D D + +++SQ ++ G ++ + ++ EY+ G L+ Sbjct 49 KIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLK 108 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G + + + +++ L YL ++ +H ++ N+LL+ G +KL+D Sbjct 109 --PGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGD-------VKLADF 159 Query 761 GVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 GV + R V W+APE + A D W G T +E+ GE P Sbjct 160 GVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDF--KADIWSLGITAIELA-KGEPPNS 216 Query 817 SRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P + + L CL +P RP+ + +L+ + Sbjct 217 DLHPMRVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRY 273 >sp|Q9M092|WAKLM_ARATH Wall-associated receptor kinase-like 17 OS=Arabidopsis thaliana OX=3702 GN=WAKL17 PE=3 SV=2 Length=786 Score = 240 bits (612), Expect = 3e-65, Method: Composition-based stats. Identities = 72/281 (26%), Positives = 116/281 (41%), Gaps = 22/281 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G G V G VAVK K + E+ IL + H H++K Sbjct 450 LGHGGQGTVYKGML-----VDGRTVAVKKSKV-IDEDKLQEFINEVVILSQINHRHVVKL 503 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-----LAQLLLFAQQICEGMAYLHA- 1016 GCC + E + LV E++ G+L ++ L A I ++YLH+ Sbjct 504 LGCCLE-TEVPI-LVYEFIINGNLFKHIHEEEADDYTMIWGMRLRIAVDIAGALSYLHSA 561 Query 1017 --QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 HRD+ + N+LLD K+ DFG +++V ++ V + PE + Sbjct 562 ASSPIYHRDIKSTNILLDEKYRAKVADFGTSRSVTIDQTHWTT--VISGTVGYVDPEYYR 619 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG---QMTVLRLTELLERG 1131 ++ SDV+SFGV L EL+T D E+I +A+ M RL+++++ Sbjct 620 SSQYTEKSDVYSFGVILAELITG-DKPVIMVQNTQEIIALAEHFRVAMKERRLSDIMDAR 678 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 R + V +L C + RP + L+ + Sbjct 679 IRDDSKPEQVMAVANLAMKCLSSRGRNRPNMREVFTELERI 719 Score = 219 bits (559), Expect = 2e-58, Method: Composition-based stats. Identities = 68/342 (20%), Positives = 123/342 (36%), Gaps = 68/342 (20%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 L +G R +L + ++ LG G + VY+G L + Sbjct 416 QQELNTRQGVVEKARIFTSKELEK---ATENFSENRVLGHGGQGTVYKGMLVDGRT---- 468 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 V +K D F ++SQ++H H+ + G C Sbjct 469 ---------------------VAVKKSKVIDEDKLQEFINEVVILSQINHRHVVKLLGCC 507 Query 678 VRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAW--KMVVAQQLASALSYLE---NKNLV 731 + I+V E++ +G L + E M W ++ +A +A ALSYL + + Sbjct 508 LETEVPILVYEFIINGNLFKHIHEEEADDYTMIWGMRLRIAVDIAGALSYLHSAASSPIY 567 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPG 786 H ++ NILL A K++D G + + ++ PE Sbjct 568 HRDIKSTNILLDEKYRA-------KVADFGTSRSVTIDQTHWTTVISGTVGYVDPEYYR- 619 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-----EHFY--QRQHRLPEPSC- 838 ++ + D + FG L E+ G+ P+ +++ EHF ++ RL + Sbjct 620 -SSQYTEKSDVYSFGVILAELI-TGDKPVIMVQNTQEIIALAEHFRVAMKERRLSDIMDA 677 Query 839 -----------PQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 +A L +CL+ RP+ R + +L R+ Sbjct 678 RIRDDSKPEQVMAVANLAMKCLSSRGRNRPNMREVFTELERI 719 >sp|Q8W1D5|CIPKP_ARATH CBL-interacting serine/threonine-protein kinase 25 OS=Arabidopsis thaliana OX=3702 GN=CIPK25 PE=2 SV=1 Length=488 Score = 233 bits (593), Expect = 3e-65, Method: Composition-based stats. Identities = 64/301 (21%), Positives = 118/301 (39%), Gaps = 26/301 (9%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 H + + + R LG+G FGKV TGE VA+K Sbjct 17 FHPDSRYQSAPTMEEEQQQLRVLFAKYEMGRLLGKGTFGKVYYG----KEITTGESVAIK 72 Query 931 ALKADCGPQH--RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 + D + K+EI I+R + H +I++ K + + + +MEYV G L Sbjct 73 IINKDQVKREGMMEQIKREISIMRLVRHPNIVELKEVMATKTK--IFFIMEYVKGGELFS 130 Query 989 YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + + + + QQ+ + + H++ HRDL N+L+D + +K+ DFGL+ Sbjct 131 KIVKGKLKEDSARKYFQQLISAVDFCHSRGVSHRDLKPENLLVDENGDLKVSDFGLSALP 190 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + + + +P + APE L++ + D+WS G+ LY LL Q Sbjct 191 EQILQDGLLHTQCGTPA-YVAPEVLRKKGYDGAKGDIWSCGIILYVLLAGFLPFQDE--- 246 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 ++++ + + E P E L+ + + R + ++ Sbjct 247 ------------NLMKMYRKIFKSE-FEYPPWFSPESKRLISKLLVVDPNKRISIPAIMR 293 Query 1168 I 1168 Sbjct 294 T 294 Score = 183 bits (465), Expect = 3e-48, Method: Composition-based stats. Identities = 54/295 (18%), Positives = 96/295 (33%), Gaps = 43/295 (15%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 RV + LG+GT VY G+ G V +K Sbjct 37 RVLFAKYEMGRLLGKGTFGKVYYGKEITTGES------------------------VAIK 72 Query 643 VLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +++ + S+M V H ++ + V + + EYV+ G L + Sbjct 73 IINKDQVKREGMMEQIKREISIMRLVRHPNIVELKEVMATKTKIFFIMEYVKGGELFSKI 132 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 +G + QQL SA+ + ++ + H ++ N+L+ G +K+SD Sbjct 133 --VKGKLKEDSARKYFQQLISAVDFCHSRGVSHRDLKPENLLVDENGD-------LKVSD 183 Query 760 PGVGLGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ + ++APE L D W G L + Sbjct 184 FGLSALPEQILQDGLLHTQCGTPAYVAPEVLRKKGYD-GAKGDIWSCGIILYVLLAGFLP 242 Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 ++ + P P+ L S+ L +P +R S I+R Sbjct 243 FQDENLMKMYRKIFKSEFEYPPWFSPESKRLISKLLVVDPNKRISIPAIMRTPWF 297 >sp|Q9XIC7|SERK2_ARATH Somatic embryogenesis receptor kinase 2 OS=Arabidopsis thaliana OX=3702 GN=SERK2 PE=1 SV=1 Length=628 Score = 236 bits (603), Expect = 3e-65, Method: Composition-based stats. Identities = 69/325 (21%), Positives = 125/325 (38%), Gaps = 20/325 (6%) Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916 R + +V + LG G FGKV Sbjct 265 WRRRKPQEFFFDVPAEEDPEVHLGQLKRFSLRELQVATDSFSNKNILGRGGFGKVYKGRL 324 Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976 G +VAVK LK + P ++ E++++ H ++++ +G C E+ L Sbjct 325 -----ADGTLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTER--LL 377 Query 977 VMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028 V Y+ GS+ L + + A G++YLH IHRD+ A N Sbjct 378 VYPYMANGSVASCLRERPPSQLPLAWSIRQQIALGSARGLSYLHDHCDPKIIHRDVKAAN 437 Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 +LLD + +GDFGLA+ + + V + APE L K +DV+ +G Sbjct 438 ILLDEEFEAVVGDFGLARLMDYKDTH--VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 495 Query 1089 VTLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 + L EL+T + + + L+ +G + +L L++ + + ++ Sbjct 496 IMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEMLVDPDLQSNYTEAEVEQLI 555 Query 1146 HLMKNCWETEASFRPTFENLIPILK 1170 + C ++ RP ++ +L+ Sbjct 556 QVALLCTQSSPMERPKMSEVVRMLE 580 Score = 199 bits (506), Expect = 1e-52, Method: Composition-based stats. Identities = 70/324 (22%), Positives = 111/324 (34%), Gaps = 67/324 (21%) Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + S V + + LG+G VY+GRL Sbjct 289 QLKRFSLRELQVATDSFSNKNILGRGGFGKVYKGRLADG--------------------- 327 Query 633 RGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 V +K L L F ++S H +L + G C+ E ++V Y+ Sbjct 328 ----TLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMA 383 Query 692 HGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745 +G + LR R +P+AW + +A A LSYL + ++H +V NILL Sbjct 384 NGSVASCLRERPPSQLPLAWSIRQQIALGSARGLSYLHDHCDPKIIHRDVKAANILLDEE 443 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800 A + D G+ ++ V I +APE L G + S D +G+ Sbjct 444 FEAV-------VGDFGLARLMDYKDTHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 494 Query 801 GATLLEICFDGEAPLQSR--SPSEKEHFYQRQHRLPEPSCPQLAT--------------- 843 G LLE+ A +R + + + L E L Sbjct 495 GIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKLEMLVDPDLQSNYTEAEVEQL 554 Query 844 --LTSQCLTYEPTQRPSFRTILRD 865 + C P +RP ++R Sbjct 555 IQVALLCTQSSPMERPKMSEVVRM 578 >sp|Q9FXF2|RKF1_ARATH Probable LRR receptor-like serine/threonine-protein kinase RFK1 OS=Arabidopsis thaliana OX=3702 GN=RKF1 PE=1 SV=1 Length=1021 Score = 243 bits (621), Expect = 3e-65, Method: Composition-based stats. Identities = 72/322 (22%), Positives = 124/322 (39%), Gaps = 19/322 (6%) Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920 + + + F +GEG FG V Sbjct 645 ICGCLPRCGRQRKDPYEEELPSGTFTLRQIKFATDDFNPTNKIGEGGFGAVFKGVL---- 700 Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 G +VAVK L + +R + EI + L H +++K G C ++ + L L EY Sbjct 701 -ADGRVVAVKQLSSKSRQGNRE-FLNEIGAISCLQHPNLVKLHGFCVERAQ--LLLAYEY 756 Query 981 VPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLD 1032 + SL L + + I +G+A+LH + ++HRD+ A N+LLD Sbjct 757 MENNSLSSALFSPKHKQIPMDWPTRFKICCGIAKGLAFLHEESPLKFVHRDIKATNILLD 816 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 D KI DFGLA+ E + + G + + APE + +DV+SFGV + Sbjct 817 KDLTPKISDFGLARLDEEEKTHISTKVAG--TIGYMAPEYALWGYLTFKADVYSFGVLVL 874 Query 1093 ELLTHCDSSQSPPTKFLE-LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 E++ +S L+ A + L ++++ R K V + C Sbjct 875 EIVAGITNSNFMGAGDSVCLLEFANECVESGHLMQVVDERLRPEVDRKEAEAVIKVALVC 934 Query 1152 WETEASFRPTFENLIPILKTVH 1173 + RP ++ +L+ ++ Sbjct 935 SSASPTDRPLMSEVVAMLEGLY 956 Score = 220 bits (561), Expect = 1e-57, Method: Composition-based stats. Identities = 64/326 (20%), Positives = 107/326 (33%), Gaps = 67/326 (21%) Query 494 PDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLP 553 D R + GA++ G G L +L C L RC Sbjct 608 SDSKPCERPK---TGMSPGAYIAIGIGAP---------CLIIFILGFLWICGCLPRCGRQ 655 Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 + + T L Q+ F + + +G+G V++G L Sbjct 656 RKDPYEEEL-------PSGTFTLRQIKF---ATDDFNPTNKIGEGGFGAVFKGVLADGR- 704 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 V +K L F +S + H +L + Sbjct 705 ------------------------VVAVKQLSSKSRQGNREFLNEIGAISCLQHPNLVKL 740 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAW--KMVVAQQLASALSYLENK-- 728 HG CV + ++ EY+E+ L L + +PM W + + +A L++L + Sbjct 741 HGFCVERAQLLLAYEYMENNSLSSALFSPKHKQIPMDWPTRFKICCGIAKGLAFLHEESP 800 Query 729 -NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPE 782 VH ++ NILL + K+SD G+ + + I ++APE Sbjct 801 LKFVHRDIKATNILLDKDLTP-------KISDFGLARLDEEEKTHISTKVAGTIGYMAPE 853 Query 783 CLPGGANSLSTAMDKWGFGATLLEIC 808 G + D + FG +LEI Sbjct 854 YALWGYLTF--KADVYSFGVLVLEIV 877 >sp|P00531|MIL_AVIMH Serine/threonine-protein kinase-transforming protein mil OS=Avian retrovirus MH2 OX=11870 GN=V-MIL PE=3 SV=1 Length=380 Score = 229 bits (583), Expect = 3e-65, Method: Composition-based stats. Identities = 79/333 (24%), Positives = 134/333 (40%), Gaps = 35/333 (11%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 + T P+ R + + +S + +G G F Sbjct 38 WSQPKTPVPAQRERAPG----TNTQEKNKIRPRGQRDSSYYWEIEASEVLLSTRIGSGSF 93 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 G V + VAVK LK D P+ ++ E+ +LR H +I+ + G Sbjct 94 GTVYKGKWHG-------DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYM- 145 Query 968 DQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ IHRD+ Sbjct 146 --TKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMK 203 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYAS 1082 + N+ L VKIGDFGLA +V E + W APE ++ F + S Sbjct 204 SNNIFLHGGLTVKIGDFGLATVKSRWSGSQQV-EQPTGSILWMAPEVIRMQDSNPFSFQS 262 Query 1083 DVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 DV+S+G+ LYEL+T + + ++G + +L + C Sbjct 263 DVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYK------------NC 310 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 P + L+ +C + RP F ++ + + Sbjct 311 PKAMKRLVADCLKKVREERPLFPQILSSIALLQ 343 Score = 220 bits (560), Expect = 4e-62, Method: Composition-based stats. Identities = 71/367 (19%), Positives = 127/367 (35%), Gaps = 62/367 (17%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 R + N I RG R S + ++ E+ + +G G+ VY+G+ Sbjct 49 RERAPGTNTQEKNKIRPRGQRDSSY--------YWEIEASEVLLSTRIGSGSFGTVYKGK 100 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQ 664 + V +K+L DP+ AF +++ + Sbjct 101 WHGD---------------------------VAVKILKVVDPTPEQFQ-AFRNEVAVLRK 132 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 H ++ G + +VT++ E L L + M + +A+Q A + Y Sbjct 133 TRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 191 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778 L KN++H ++ NI L +K+ D G+ G+ E+ I W Sbjct 192 LHAKNIIHRDMKSNNIFL-------HGGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILW 244 Query 779 LAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------ 831 +APE + +N S D + +G L E+ GE P + ++ F + Sbjct 245 MAPEVIRMQDSNPFSFQSDVYSYGIVLYELM-TGELPYSHINNRDQIIFMVGRGYASPDL 303 Query 832 -RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 +L + + L + CL +RP F IL + LQ + + S Sbjct 304 SKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSIALLQHSLPKINRSASEPSLHRASH 363 Query 891 VFHKRYL 897 Sbjct 364 TEDINSC 370 >sp|Q942F3|BRI1_ORYSJ Brassinosteroid LRR receptor kinase BRI1 OS=Oryza sativa subsp. japonica OX=39947 GN=BRI1 PE=1 SV=1 Length=1121 Score = 244 bits (624), Expect = 4e-65, Method: Composition-based stats. Identities = 73/288 (25%), Positives = 123/288 (43%), Gaps = 21/288 (7%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +G G FG V G++VA+K L G R + E++ + + H Sbjct 807 FHIACQIGSGGFGDVYKAQLK-----DGKVVAIKKLIHVSGQGDRE-FTAEMETIGKIKH 860 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGM 1011 +++ G C+ E+ LV +Y+ GSL D L + A G+ Sbjct 861 RNLVPLLGYCKAGEER--LLVYDYMKFGSLEDVLHDRKKIGKKLNWEARRKIAVGAARGL 918 Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 A+LH H IHRD+ + NVL+D ++ DFG+A+ + + V +P + Sbjct 919 AFLHHNCIPHIIHRDMKSSNVLIDEQLEARVSDFGMARLMSVVDTHLSVSTLAGTP-GYV 977 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLRLTEL 1127 PE + ++ DV+S+GV L ELLT + S + L+G + Q T L++T++ Sbjct 978 PPEYYQSFRCTTKGDVYSYGVVLLELLTGKPPTDSADFGEDNNLVGWVK-QHTKLKITDV 1036 Query 1128 LERGERLPRPDKCPCEVYHL--MKNCWETEASFRPTFENLIPILKTVH 1173 + P + HL C + S RPT ++ + K + Sbjct 1037 FDPELLKEDPSVELELLEHLKIACACLDDRPSRRPTMLKVMAMFKEIQ 1084 Score = 207 bits (528), Expect = 2e-53, Method: Composition-based stats. Identities = 53/317 (17%), Positives = 108/317 (34%), Gaps = 66/317 (21%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +G G +VY+ +L+ V +K L Sbjct 803 ATNGFHIACQIGSGGFGDVYKAQLKDGK-------------------------VVAIKKL 837 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER- 703 F + ++ H +L + G C G E ++V +Y++ G L+ L + Sbjct 838 IHVSGQGDREFTAEMETIGKIKHRNLVPLLGYCKAGEERLLVYDYMKFGSLEDVLHDRKK 897 Query 704 --GHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + + +A A L++L + +++H ++ N+L+ A ++S Sbjct 898 IGKKLNWEARRKIAVGAARGLAFLHHNCIPHIIHRDMKSSNVLIDEQLEA-------RVS 950 Query 759 DPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 D G+ LS ++ PE + +T D + +G LLE+ G+ Sbjct 951 DFGMARLMSVVDTHLSVSTLAGTPGYVPPEYYQ--SFRCTTKGDVYSYGVVLLELL-TGK 1007 Query 813 APLQSRSPSEKEHF-----YQRQHRLPEPSCPQL--------------ATLTSQCLTYEP 853 P S E + + ++ + P+L + CL P Sbjct 1008 PPTDSADFGEDNNLVGWVKQHTKLKITDVFDPELLKEDPSVELELLEHLKIACACLDDRP 1067 Query 854 TQRPSFRTILRDLTRLQ 870 ++RP+ ++ +Q Sbjct 1068 SRRPTMLKVMAMFKEIQ 1084 >sp|Q9LN59|WAKLK_ARATH Putative wall-associated receptor kinase-like 11 OS=Arabidopsis thaliana OX=3702 GN=WAKL11 PE=3 SV=2 Length=788 Score = 240 bits (612), Expect = 4e-65, Method: Composition-based stats. Identities = 74/293 (25%), Positives = 121/293 (41%), Gaps = 22/293 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G G V G VAVK K + E+ IL + H H++K Sbjct 457 LGQGGQGTVYKGML-----VDGRTVAVKKSKV-VDEDKLEEFINEVVILSQINHRHVVKL 510 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA-- 1016 GCC + + LV E++P G+L ++ S L A I ++YLH+ Sbjct 511 LGCCLETEVPT--LVYEFIPNGNLFQHIHEESDDYTKTWGMRLRIAVDIAGALSYLHSAA 568 Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 HRD+ + N+LLD K+ DFG +++V H ++ V + PE Sbjct 569 SSPIYHRDIKSTNILLDEKYRTKVSDFGTSRSVTIDHTHWTT--VISGTVGYVDPEYYGS 626 Query 1076 YKFYYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 ++ SDV+SFGV L EL+T + S + L + M R E+++ R Sbjct 627 SQYTDKSDVYSFGVVLVELITGEKPVITVSNSQEIRGLADHFRVAMKENRFFEIMDARIR 686 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 + V +L + C ++ RP + L+ + Q S+ ++ Sbjct 687 DGCKPEQVMAVANLARRCLNSKGKKRPCMRKVFTDLEKI---LASQEDSLVNI 736 Score = 230 bits (586), Expect = 7e-62, Method: Composition-based stats. Identities = 70/341 (21%), Positives = 121/341 (35%), Gaps = 67/341 (20%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 L +G R + +L ++ LGQG + VY+G L + Sbjct 423 QQQLNTNKGNVEKTRIFSSRELEK---ATDNFSESRILGQGGQGTVYKGMLVDGRT---- 475 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 V +K D F ++SQ++H H+ + G C Sbjct 476 ---------------------VAVKKSKVVDEDKLEEFINEVVILSQINHRHVVKLLGCC 514 Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVH 732 + +V E++ +G L + E W ++ +A +A ALSYL + + H Sbjct 515 LETEVPTLVYEFIPNGNLFQHIHEESDDYTKTWGMRLRIAVDIAGALSYLHSAASSPIYH 574 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGG 787 ++ NILL K+SD G + ++ PE G Sbjct 575 RDIKSTNILLDEKYRT-------KVSDFGTSRSVTIDHTHWTTVISGTVGYVDPEYY--G 625 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS---------------EKEHFYQRQHR 832 ++ + D + FG L+E+ GE P+ + S S E F R Sbjct 626 SSQYTDKSDVYSFGVVLVELI-TGEKPVITVSNSQEIRGLADHFRVAMKENRFFEIMDAR 684 Query 833 LPEPSCPQ----LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + P+ +A L +CL + +RP R + DL ++ Sbjct 685 IRDGCKPEQVMAVANLARRCLNSKGKKRPCMRKVFTDLEKI 725 >sp|P23437|CDK2_XENLA Cyclin-dependent kinase 2 OS=Xenopus laevis OX=8355 GN=cdk2 PE=1 SV=3 Length=297 Score = 226 bits (575), Expect = 4e-65, Method: Composition-based stats. Identities = 72/288 (25%), Positives = 127/288 (44%), Gaps = 28/288 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ Sbjct 1 MENFQKVEKIGEGTYGVV----YKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICE 1009 L H +I+K E L LV E++ L+ ++ +I LA + + Q+ + Sbjct 57 ELNHPNIVKLLDVI--HTENKLYLVFEFL-NQDLKKFMDGSNISGISLALVKSYLFQLLQ 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 G+A+ H+ +HRDL +N+L+++D +K+ DFGLA+A R +++ A Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINSDGAIKLADFGLARAFGVP---VRTFTHEVVTLWYRA 170 Query 1070 PECLKEYK-FYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIA-----QGQ 1118 PE L K + A D+WS G E++T DS + +G G Sbjct 171 PEILLGCKFYSTAVDIWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDEVSWPGV 230 Query 1119 MTVLRLTELLERGERLPRPDKCPC---EVYHLMKNCWETEASFRPTFE 1163 T+ + R P + L+ + +++ R + + Sbjct 231 TTMPDYKSTFPKWIRQDFSKVVPPLDEDGRDLLAQMLQYDSNKRISAK 278 Score = 174 bits (441), Expect = 4e-47, Method: Composition-based stats. Identities = 50/266 (19%), Positives = 95/266 (36%), Gaps = 40/266 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 + ++ +G+GT VY+ R R G V LK Sbjct 1 MENFQKVEKIGEGTYGVVYKARNRETGE------------------------IVALKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 LD + SL+ +++H ++ + V + +V E++ + L ++ Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-NQDLKKFMDGSN 95 Query 704 GH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + +A QL L++ + ++H ++ +N+L+ G IKL+D G+ Sbjct 96 ISGISLALVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINSDGA-------IKLADFGL 148 Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + + APE L G STA+D W G E+ Sbjct 149 ARAFGVPVRTFTHEVVTLWYRAPEILLGCKF-YSTAVDIWSLGCIFAEMITRRALFPGDS 207 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ E S P + T+ Sbjct 208 EIDQLFRIFRTLGTPDEVSWPGVTTM 233 >sp|Q8VDG6|M3K21_MOUSE Mitogen-activated protein kinase kinase kinase 21 OS=Mus musculus OX=10090 GN=Map3k21 PE=1 SV=2 Length=1002 Score = 243 bits (620), Expect = 4e-65, Method: Composition-based stats. Identities = 88/306 (29%), Positives = 129/306 (42%), Gaps = 54/306 (18%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR---SGWKQEIDILRTLYHEHI 959 +G G FG+V + G+ VAVKA + D ++E + L H +I Sbjct 116 IGAGGFGQVYRATWQ------GQEVAVKAARRDPEQDAAAAAESVRREARLFAMLRHPNI 169 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-------------IGLAQLLLFAQQ 1006 I+ +G C Q L LV+E+ G+L L + I L+ +A Q Sbjct 170 IQLRGVCLRQ--PHLCLVLEFARGGALNRALAAAASDPRAPGPRRARRIPPQVLVNWAVQ 227 Query 1007 ICEGMAYLHAQ---HYIHRDLAARNVLLDN--------DRLVKIGDFGLAKAVPEGHEYY 1055 I GM YLH + +HRDL + N+LL ++ +KI DFGLA+ + Sbjct 228 IARGMLYLHEEAVVPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLAR-----EWHR 282 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 R W APE ++ F SD+WS+GV L+ELLT P + ++ + +A Sbjct 283 TTRMSAAGTYAWMAPEVIRSSLFSKGSDIWSYGVLLWELLTG-----EVPYRGIDGLAVA 337 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 G LP P CP LMK CWE + RP+F ++ L + E Sbjct 338 YGVAVN---------KLTLPIPSTCPEPFAKLMKECWEQDPHIRPSFALILQQLTAIEEA 388 Query 1176 YQGQAP 1181 P Sbjct 389 VLTNMP 394 Score = 211 bits (536), Expect = 1e-54, Method: Composition-based stats. Identities = 67/338 (20%), Positives = 114/338 (34%), Gaps = 53/338 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 VD + + +G G VY Q V +K Sbjct 105 VDFERLELKELIGAGGFGQVYRATW--------------------------QGQEVAVKA 138 Query 644 LDPSHHD----IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG------ 693 A + A L + + H ++ + GVC+R P +V E+ G Sbjct 139 ARRDPEQDAAAAAESVRREARLFAMLRHPNIIQLRGVCLRQPHLCLVLEFARGGALNRAL 198 Query 694 -----PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV---HGNVCGRNILLARL 745 R +P + A Q+A + YL + +V H ++ NILL Sbjct 199 AAAASDPRAPGPRRARRIPPQVLVNWAVQIARGMLYLHEEAVVPILHRDLKSSNILLLEK 258 Query 746 GLAEGT-SPFIKLSDPGVGLG--ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 + + +K++D G+ +R W+APE + S D W +G Sbjct 259 IEHDDICNKTLKITDFGLAREWHRTTRMSAAGTYAWMAPEVIRSSL--FSKGSDIWSYGV 316 Query 803 TLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859 L E+ GE P + + + +P A L +C +P RPSF Sbjct 317 LLWELL-TGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLMKECWEQDPHIRPSF 375 Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897 IL+ LT ++ L ++ + S D + ++ Sbjct 376 ALILQQLTAIEEAVLTNMPQESFHSMQEDWKLEIQQMF 413 >sp|Q5JZY3|EPHAA_HUMAN Ephrin type-A receptor 10 OS=Homo sapiens OX=9606 GN=EPHA10 PE=1 SV=2 Length=1008 Score = 243 bits (621), Expect = 4e-65, Method: Composition-based stats. Identities = 84/275 (31%), Positives = 125/275 (45%), Gaps = 21/275 (8%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG G FG++ C +VAV L+ R G+ E L H HI++ Sbjct 650 SLGGGRFGELCCGCLQLPGRQE-LLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVR 708 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL--AQLLLFAQQICEGMAYLHAQHY 1019 +G +L +V EY+ G+L +L RH L QL+ + M YL Y Sbjct 709 LEGVVTRGS--TLMIVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGY 766 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HR LAAR+VL+ +D + KI FG + + E G SP W APE L+ F Sbjct 767 VHRGLAARHVLVSSDLVCKISGFG--RGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFS 824 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 ASDVWSFG+ ++E++ + M+ + + +E G RLP P Sbjct 825 SASDVWSFGIIMWEVMAFGER--------------PYWDMSGQDVIKAVEDGFRLPPPRN 870 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 CP ++ LM +CW+ + RP F + IL + + Sbjct 871 CPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQ 905 Score = 233 bits (595), Expect = 7e-62, Method: Composition-based stats. Identities = 92/343 (27%), Positives = 130/343 (38%), Gaps = 49/343 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +D K +T LG G + G L++ G QEL V + Sbjct 638 KELDAKSVTLERSLGGGRFGELCCGCLQLPGR---------------------QELLVAV 676 Query 642 KVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 +L S D F A + Q H+H+ + GV RG ++VTEY+ HG LD +LR Sbjct 677 HMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLR 736 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 R G + M + LASA+ YL VH + R++L++ + K+S Sbjct 737 RHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVS-------SDLVCKIS-- 787 Query 761 GVGLGALSREERVERIP-------WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G G G R E V W APE L G S+A D W FG + E+ GE Sbjct 788 GFGRGPRDRSEAVYTTMSGRSPALWAAPETLQFG--HFSSASDVWSFGIIMWEVMAFGER 845 Query 814 PLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P S + + RLP P +CP L L C +P +RP F I L+++ Sbjct 846 PYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQ 905 Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 + P FG V + Sbjct 906 DPEPPKCALTTCPRPPTPLADRAFSTFP-------SFGSVGAW 941 >sp|O00506|STK25_HUMAN Serine/threonine-protein kinase 25 OS=Homo sapiens OX=9606 GN=STK25 PE=1 SV=1 Length=426 Score = 230 bits (587), Expect = 4e-65, Method: Composition-based stats. Identities = 72/290 (25%), Positives = 124/290 (43%), Gaps = 24/290 (8%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + V + K+ +G+G FG+V Y ++ T E+VA+K + + Sbjct 1 MAHLRGFANQHSRVDPEELFTKLDRIGKGSFGEV----YKGIDNHTKEVVAIKIIDLEEA 56 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL 997 +QEI +L +I +Y G + L ++MEY+ GS D L + Sbjct 57 EDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTK--LWIIMEYLGGGSALDLLKPGPLEE 114 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + ++I +G+ YLH++ IHRD+ A NVLL VK+ DFG+A + + Sbjct 115 TYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD---TQIK 171 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 R FW APE +K+ + + +D+WS G+T EL + PP Sbjct 172 RNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIEL-----AKGEPP----------NS 216 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + +R+ L+ + + ++ C + FRPT + L+ Sbjct 217 DLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLK 266 Score = 201 bits (511), Expect = 5e-55, Method: Composition-based stats. Identities = 60/297 (20%), Positives = 110/297 (37%), Gaps = 44/297 (15%) Query 583 RVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 RVD +E T+L +G+G+ VY+G D + V + Sbjct 13 RVDPEELFTKLDRIGKGSFGEVYKGI------------------------DNHTKEVVAI 48 Query 642 KVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K++D D + +++SQ ++ G ++ + ++ EY+ G L+ Sbjct 49 KIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLK 108 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G + + + +++ L YL ++ +H ++ N+LL+ G +KL+D Sbjct 109 --PGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGD-------VKLADF 159 Query 761 GVG----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 GV + R V W+APE + A D W G T +E+ GE P Sbjct 160 GVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDF--KADIWSLGITAIELA-KGEPPNS 216 Query 817 SRSPSEKEHFYQRQ--HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P + L CL +P RP+ + +L+ + Sbjct 217 DLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRY 273 >sp|Q7G768|BRL2_ORYSJ Brassinosteroid LRR receptor kinase BRL2 OS=Oryza sativa subsp. japonica OX=39947 GN=BRL2 PE=2 SV=1 Length=1110 Score = 244 bits (623), Expect = 5e-65, Method: Composition-based stats. Identities = 72/283 (25%), Positives = 120/283 (42%), Gaps = 24/283 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG+V G VA+K L Q + E++ L + H++++ Sbjct 830 IGSGGFGEVFKATLK-----DGSCVAIKKL-IHLSYQGDREFMAEMETLGKIKHKNLVPL 883 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-------IGLAQLLLFAQQICEGMAYLH 1015 G C+ E+ LV E++ GSL D L + Q A+ G+ +LH Sbjct 884 LGYCKIGEER--LLVYEFMSHGSLEDTLHGDGGRSASPAMSWEQRKKVARGAARGLCFLH 941 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 H IHRD+ + NVLLD D ++ DFG+A+ + + V +P + PE Sbjct 942 YNCIPHIIHRDMKSSNVLLDGDMEARVADFGMARLISALDTHLSVSTLAGTP-GYVPPEY 1000 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + ++ DV+SFGV L ELLT + L+G + ++ E+L+ Sbjct 1001 YQSFRCTVKGDVYSFGVVLLELLTGRRPTDKDDFGDTNLVGWVKMKVGDGAGKEVLDPEL 1060 Query 1133 RLPRPDKCPCEVYHLM---KNCWETEASFRPTFENLIPILKTV 1172 + D E+ M C + S RP ++ +L+ + Sbjct 1061 VVEGAD--ADEMARFMDMALQCVDDFPSKRPNMLQVVAMLREL 1101 Score = 205 bits (522), Expect = 1e-52, Method: Composition-based stats. Identities = 55/330 (17%), Positives = 110/330 (33%), Gaps = 69/330 (21%) Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L +L+F ++ + S +G G V++ L+ Sbjct 808 QLRKLTFTQLIEATNGFSTASLIGSGGFGEVFKATLKDGSC------------------- 848 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 V +K L + F + ++ H +L + G C G E ++V E++ H Sbjct 849 ------VAIKKLIHLSYQGDREFMAEMETLGKIKHKNLVPLLGYCKIGEERLLVYEFMSH 902 Query 693 GPLDVWLRRERGH-----VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744 G L+ L + G + + VA+ A L +L +++H ++ N+LL Sbjct 903 GSLEDTLHGDGGRSASPAMSWEQRKKVARGAARGLCFLHYNCIPHIIHRDMKSSNVLLD- 961 Query 745 LGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKW 798 +++D G+ LS ++ PE + + D + Sbjct 962 ------GDMEARVADFGMARLISALDTHLSVSTLAGTPGYVPPEYYQ--SFRCTVKGDVY 1013 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE------------------PSCPQ 840 FG LLE+ G P + + ++ + + Sbjct 1014 SFGVVLLELL-TGRRPTDKDDFGDTNLVGWVKMKVGDGAGKEVLDPELVVEGADADEMAR 1072 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + QC+ P++RP+ ++ L L Sbjct 1073 FMDMALQCVDDFPSKRPNMLQVVAMLRELD 1102 >sp|Q9M1Z9|LRK58_ARATH Putative L-type lectin-domain containing receptor kinase V.8 OS=Arabidopsis thaliana OX=3702 GN=LECRK58 PE=3 SV=1 Length=626 Score = 236 bits (601), Expect = 5e-65, Method: Composition-based stats. Identities = 88/408 (22%), Positives = 155/408 (38%), Gaps = 25/408 (6%) Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838 L+P L + + GA + + +P+ + P+ S Sbjct 185 LSPYFLEEMYYGYTASTG--SIGAFHYMLSSYATP--KVENPTWEFIVVPTLPPYPKKSS 240 Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD----VLTVNPDSPASDPTVFHK 894 + + + CLT I + P A + Sbjct 241 DRTKKILAVCLTLAVFAVFVASGICFVFYTRHKKVKEVLEEWEIQYGPHRFAYKELLNAT 300 Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 + K+ + LG+G FG+V + T G+ +AVK D Q S + EI + L Sbjct 301 KDFKEKQLLGKGGFGQV----FKGTLPGSNAEIAVKRTSHD-SRQGMSEFLAEISTIGRL 355 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----SIGLAQLLLFAQQICEG 1010 H ++++ G C + ++L LV ++ P GSL YL R+ + Q + + Sbjct 356 RHPNLVRLLGYCRHK--ENLYLVYDFTPNGSLDKYLDRNENQERLTWEQRFKIIKDVASA 413 Query 1011 MAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + +LH + IHRD+ NVL+D++ +IGDFGLAK +G + R G + Sbjct 414 LLHLHQEWVQIIIHRDIKPANVLIDHEMNARIGDFGLAKLYDQGLDPQTSRVAG--TFGY 471 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTE 1126 APE L+ + ++DV++FG+ + E++ + P L+ +L + Sbjct 472 IAPELLRTGRATTSTDVYAFGLVMLEVVCGRRMIERRAPENEEVLVDWILELWESGKLFD 531 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 E R + + L C RP ++ IL V + Sbjct 532 AAEESIRQEQNRGEIELLLKLGLLCAHHTELIRPNMSAVMQILNGVSQ 579 Score = 211 bits (538), Expect = 1e-56, Method: Composition-based stats. Identities = 49/261 (19%), Positives = 93/261 (36%), Gaps = 44/261 (17%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 K+ + LG+G V++G L G + +K Sbjct 299 ATKDFKEKQLLGKGGFGQVFKGTL------------------------PGSNAEIAVKRT 334 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 F S + ++ H +L + G C +V ++ +G LD +L R Sbjct 335 SHDSRQGMSEFLAEISTIGRLRHPNLVRLLGYCRHKENLYLVYDFTPNGSLDKYLDRNEN 394 Query 705 HVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + W + + + +ASAL +L + ++H ++ N+L+ ++ D Sbjct 395 QERLTWEQRFKIIKDVASALLHLHQEWVQIIIHRDIKPANVLIDHE-------MNARIGD 447 Query 760 PGVGLGA-----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ ++APE L G +T+ D + FG +LE+ G Sbjct 448 FGLAKLYDQGLDPQTSRVAGTFGYIAPELLRTGRA--TTSTDVYAFGLVMLEVVC-GRRM 504 Query 815 LQSRSPSEKEHFYQRQHRLPE 835 ++ R+P +E L E Sbjct 505 IERRAPENEEVLVDWILELWE 525 >sp|Q00655|KSYK_PIG Tyrosine-protein kinase SYK OS=Sus scrofa OX=9823 GN=SYK PE=1 SV=1 Length=628 Score = 236 bits (601), Expect = 5e-65, Method: Composition-based stats. Identities = 99/325 (30%), Positives = 144/325 (44%), Gaps = 23/325 (7%) Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY--LKKIRDLGEGHF 908 YE + P L V+ R + ++LG G+F Sbjct 316 YESDRGPWANEREAQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNF 375 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 G V Y V + LK + P + E ++++ L + +I++ G CE Sbjct 376 GTVKKGYYQMKKVVKTVAVKI--LKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICE 433 Query 968 DQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 +S LVME LG L YL ++ + ++ Q+ GM YL +++HRDLAA Sbjct 434 ---AESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEECNFVHRDLAA 490 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 RNVLL KI DFGL+KA+ YY+ + G PV WYAPEC+ YKF SDVWS Sbjct 491 RNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWS 550 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 FGV ++E ++ M ++ +LE+GER+ P CP E+Y Sbjct 551 FGVLMWEAFSYGQK--------------PYRGMKGSEVSAMLEKGERMGCPPGCPREMYE 596 Query 1147 LMKNCWETEASFRPTFENLIPILKT 1171 LM CW + RP F + L+ Sbjct 597 LMTLCWTYDVENRPGFVAVELRLRN 621 Score = 206 bits (525), Expect = 5e-55, Method: Composition-based stats. Identities = 66/290 (23%), Positives = 114/290 (39%), Gaps = 40/290 (14%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + LG G V +G +++ K+ + P LK Sbjct 366 EDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDP----------ALK-------- 407 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 A++M Q+ + ++ + G+C ++V E E GPL+ +L++ R HV Sbjct 408 --DELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNR-HVKDKN 463 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 + + Q++ + YLE N VH ++ RN+LL T + K+SD G+ + E Sbjct 464 IIELVHQVSMGMKYLEECNFVHRDLAARNVLL-------VTQHYAKISDFGLSKALRADE 516 Query 771 ERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + + W APEC+ S+ D W FG + E G+ P + SE Sbjct 517 NYYKAQTHGKWPVKWYAPECI--NYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEV 574 Query 824 EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 ++ R+ P ++ L + C TY+ RP F + L Sbjct 575 SAMLEKGERMGCPPGCPREMYELMTLCWTYDVENRPGFVAVELRLRNYYY 624 >sp|Q9S9M2|WAKLD_ARATH Wall-associated receptor kinase-like 4 OS=Arabidopsis thaliana OX=3702 GN=WAKL4 PE=2 SV=2 Length=761 Score = 239 bits (609), Expect = 5e-65, Method: Composition-based stats. Identities = 74/287 (26%), Positives = 114/287 (40%), Gaps = 18/287 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R LG+G G V G +VAVK KA + E+ +L + Sbjct 422 DNFNTNRVLGQGGQGTVYKGML-----VDGRIVAVKRSKA-MDEDKVEEFINEVVVLAQI 475 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEG 1010 H +I+K GCC + + LV E+VP G L L + L A +I Sbjct 476 NHRNIVKLLGCCLET--EVPVLVYEFVPNGDLCKRLRDECDDYIMTWEVRLHIAIEIAGA 533 Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 ++YLH+ HRD+ N+LLD VK+ DFG +++V + + G + Sbjct 534 LSYLHSAASFPIYHRDIKTTNILLDEKYQVKVSDFGTSRSVTIDQTHLTTQVAG--TFGY 591 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHC-DSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 PE + KF SDV+SFGV L EL+T SS+ + + R + Sbjct 592 VDPEYFQSSKFTDKSDVYSFGVVLVELITGKNPSSRVQSEENRGFAAHFVAAVKENRFLD 651 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 +++ + V L K C + RP + L+ + Sbjct 652 IVDERIKDECNLDQVMAVAKLAKRCLNRKGKKRPNMREVSVELERIR 698 Score = 219 bits (557), Expect = 3e-58, Method: Composition-based stats. Identities = 65/340 (19%), Positives = 117/340 (34%), Gaps = 63/340 (19%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 LGQG + VY+G L V +K Sbjct 420 ATDNFNTNRVLGQGGQGTVYKGMLVDGRI-------------------------VAVKRS 454 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D F +++Q++H ++ + G C+ ++V E+V +G L LR E Sbjct 455 KAMDEDKVEEFINEVVVLAQINHRNIVKLLGCCLETEVPVLVYEFVPNGDLCKRLRDECD 514 Query 705 HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 M W ++ +A ++A ALSYL + + H ++ NILL +K+SD Sbjct 515 DYIMTWEVRLHIAIEIAGALSYLHSAASFPIYHRDIKTTNILLDEKYQ-------VKVSD 567 Query 760 PGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G + ++ PE ++ + D + FG L+E+ G+ P Sbjct 568 FGTSRSVTIDQTHLTTQVAGTFGYVDPEYFQ--SSKFTDKSDVYSFGVVLVELI-TGKNP 624 Query 815 LQSRSPSEKEHFYQR--------------QHRLPEPSC----PQLATLTSQCLTYEPTQR 856 E F R+ + +A L +CL + +R Sbjct 625 SSRVQSEENRGFAAHFVAAVKENRFLDIVDERIKDECNLDQVMAVAKLAKRCLNRKGKKR 684 Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896 P+ R + +L R++ + + + D D + Sbjct 685 PNMREVSVELERIRSSSYKSEIHNDDDDDDDDDDEDDQAM 724 >sp|Q54R58|YTYK2_DICDI Probable tyrosine-protein kinase DDB_G0283397 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0283397 PE=3 SV=1 Length=918 Score = 241 bits (616), Expect = 6e-65, Method: Composition-based stats. Identities = 83/284 (29%), Positives = 123/284 (43%), Gaps = 37/284 (13%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK--ADCGPQHRSGWKQEIDILRTLYHEHI 959 ++G+G FGKV + G+ VA+K + + +E+ I+ L H Sbjct 182 EIGQGFFGKVYKARWR------GKSVALKKITLIKFRDLTETEIFDKEVSIMSKLCHPTC 235 Query 960 IKYKGCCE-DQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLH 1015 + + G C D ++MEY+ GSLR L S + + L A+ I EGM YLH Sbjct 236 VMFIGACSLDGPSNDRSIIMEYMEGGSLRRLLDEKSSYHLPPSLQLSIARDIAEGMNYLH 295 Query 1016 AQ----HYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 +HRDL + N+LL++ V KI DFGL+K + G + W AP Sbjct 296 TNFKEGPIVHRDLTSSNILLNSSYTVAKINDFGLSKEMKPGPTE---MTAAMGSLAWMAP 352 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE- 1129 EC K + DV+SF + L+E++T D M LRL L Sbjct 353 ECFKAENYTEKVDVYSFAIILWEIVTCRDP---------------YNGMEPLRLAFLASV 397 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 RLP + P L+ CW S RP+F+ ++ IL + Sbjct 398 EDYRLPL-NGFPPYWVELISKCWNITPSLRPSFKEILQILNQIE 440 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 73/308 (24%), Positives = 122/308 (40%), Gaps = 46/308 (15%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S L H + +E+T +GQG VY+ R R G+ + Sbjct 165 STLKKHEIPSRELTVEKEIGQGFFGKVYKARWR--------------------GKSVALK 204 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE---NIMVTEYVEHG 693 ++K D + +I F + S+MS++ H G C ++ EY+E G Sbjct 205 KITLIKFRDLTETEI---FDKEVSIMSKLCHPTCVMFIGACSLDGPSNDRSIIMEYMEGG 261 Query 694 PLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENK----NLVHGNVCGRNILLARLGLA 748 L L + H+P + ++ +A+ +A ++YL +VH ++ NILL Sbjct 262 SLRRLLDEKSSYHLPPSLQLSIARDIAEGMNYLHTNFKEGPIVHRDLTSSNILLNSSYT- 320 Query 749 EGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 K++D G+ G + + W+APEC A + + +D + F L Sbjct 321 -----VAKINDFGLSKEMKPGPTEMTAAMGSLAWMAPECFK--AENYTEKVDVYSFAIIL 373 Query 805 LEICFDGEAPLQSRSPSEKEHF-YQRQHRLP-EPSCPQLATLTSQCLTYEPTQRPSFRTI 862 EI P P +RLP P L S+C P+ RPSF+ I Sbjct 374 WEIVTC-RDPYNGMEPLRLAFLASVEDYRLPLNGFPPYWVELISKCWNITPSLRPSFKEI 432 Query 863 LRDLTRLQ 870 L+ L +++ Sbjct 433 LQILNQIE 440 >sp|C0LGN2|Y3148_ARATH Probable leucine-rich repeat receptor-like serine/threonine-protein kinase At3g14840 OS=Arabidopsis thaliana OX=3702 GN=LRR-RLK PE=1 SV=1 Length=1020 Score = 243 bits (619), Expect = 6e-65, Method: Composition-based stats. Identities = 77/310 (25%), Positives = 117/310 (38%), Gaps = 19/310 (6%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 Q L S + +GEG FG V G ++AV Sbjct 645 QMEKDFKNLDFQISSFSLRQIKVATDNFDPANKIGEGGFGPVHKGI-----MTDGTVIAV 699 Query 930 KALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 K L A Q + EI ++ L H H++K GCC + + L LV EY+ SL Sbjct 700 KQLSAK-SKQGNREFLNEIAMISALQHPHLVKLYGCCVEGDQ--LLLVYEYLENNSLARA 756 Query 990 L-----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGD 1041 L + + I G+AYLH + +HRD+ A NVLLD + KI D Sbjct 757 LFGPQETQIPLNWPMRQKICVGIARGLAYLHEESRLKIVHRDIKATNVLLDKELNPKISD 816 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLAK E + + R G + APE +DV+SFGV E++ ++ Sbjct 817 FGLAKLDEEENTHISTRVAG--TYGYMAPEYAMRGHLTDKADVYSFGVVALEIVHGKSNT 874 Query 1102 QSP-PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 S L+ L E+++ + + + C RP Sbjct 875 SSRSKADTFYLLDWVHVLREQNTLLEVVDPRLGTDYNKQEALMMIQIGMLCTSPAPGDRP 934 Query 1161 TFENLIPILK 1170 + ++ +L+ Sbjct 935 SMSTVVSMLE 944 Score = 230 bits (587), Expect = 8e-61, Method: Composition-based stats. Identities = 60/314 (19%), Positives = 112/314 (36%), Gaps = 52/314 (17%) Query 536 CLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHL 595 L+ R C P+ + + ++ L +V + + Sbjct 625 FLVLLIGGILWWRGCLRPKSQMEKDF------KNLDFQISSFSLRQIKVATDNFDPANKI 678 Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655 G+G V++G + + +K L F Sbjct 679 GEGGFGPVHKGIMTDG-------------------------TVIAVKQLSAKSKQGNREF 713 Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KM 712 +++S + H HL ++G CV G + ++V EY+E+ L L + +P+ W + Sbjct 714 LNEIAMISALQHPHLVKLYGCCVEGDQLLLVYEYLENNSLARALFGPQETQIPLNWPMRQ 773 Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR 769 + +A L+YL + +VH ++ N+LL + K+SD G+ Sbjct 774 KICVGIARGLAYLHEESRLKIVHRDIKATNVLLDKELNP-------KISDFGLAKLDEEE 826 Query 770 EERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + ++APE G L+ D + FG LEI G++ SRS ++ Sbjct 827 NTHISTRVAGTYGYMAPEYAMRG--HLTDKADVYSFGVVALEIV-HGKSNTSSRSKADTF 883 Query 825 HFYQRQHRLPEPSC 838 + H L E + Sbjct 884 YLLDWVHVLREQNT 897 >sp|Q9SKG5|SERK4_ARATH Somatic embryogenesis receptor kinase 4 OS=Arabidopsis thaliana OX=3702 GN=SERK4 PE=1 SV=2 Length=620 Score = 235 bits (600), Expect = 7e-65, Method: Composition-based stats. Identities = 71/325 (22%), Positives = 123/325 (38%), Gaps = 20/325 (6%) Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916 R + +V + LG G FGKV Sbjct 254 WLRRKPQDHFFDVPAEEDPEVHLGQLKRFTLRELLVATDNFSNKNVLGRGGFGKVYKGRL 313 Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976 G +VAVK LK + ++ E++++ H ++++ +G C E+ L Sbjct 314 -----ADGNLVAVKRLKEERTKGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTER--LL 366 Query 977 VMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARN 1028 V Y+ GS+ L + + A G+AYLH IHRD+ A N Sbjct 367 VYPYMANGSVASCLRERPEGNPALDWPKRKHIALGSARGLAYLHDHCDQKIIHRDVKAAN 426 Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 +LLD + +GDFGLAK + + V + APE L K +DV+ +G Sbjct 427 ILLDEEFEAVVGDFGLAKLMNYNDSH--VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYG 484 Query 1089 VTLYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 V L EL+T + + + L+ + + +L L++ + ++ Sbjct 485 VMLLELITGQKAFDLARLANDDDIMLLDWVKEVLKEKKLESLVDAELEGKYVETEVEQLI 544 Query 1146 HLMKNCWETEASFRPTFENLIPILK 1170 + C ++ A RP ++ +L+ Sbjct 545 QMALLCTQSSAMERPKMSEVVRMLE 569 Score = 194 bits (492), Expect = 8e-51, Method: Composition-based stats. Identities = 68/341 (20%), Positives = 122/341 (36%), Gaps = 50/341 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V + + LG+G VY+GRL V +K Sbjct 289 VATDNFSNKNVLGRGGFGKVYKGRLADGN-------------------------LVAVKR 323 Query 644 LDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-R 701 L L F ++S H +L + G C+ E ++V Y+ +G + LR R Sbjct 324 LKEERTKGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMANGSVASCLRER 383 Query 702 ERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 G+ + W + +A A L+YL ++ ++H +V NILL A Sbjct 384 PEGNPALDWPKRKHIALGSARGLAYLHDHCDQKIIHRDVKAANILLDEEFEAV------- 436 Query 757 LSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 + D G+ + V I +APE L G + S D +G+G LLE+ Sbjct 437 VGDFGLAKLMNYNDSHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGYGVMLLELITGQ 494 Query 812 EAPLQSR--SPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFRTILRDLT 867 +A +R + + + L E L A L + + E Q + + Sbjct 495 KAFDLARLANDDDIMLLDWVKEVLKEKKLESLVDAELEGKYVETEVEQLIQMALLCTQSS 554 Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 ++ +++V+ + ++ ++ I D + Sbjct 555 AMERPKMSEVVRMLEGDGLAERWEEWQKEEMPIHDFNYQAY 595 >sp|Q5E9L6|STK4_BOVIN Serine/threonine-protein kinase 4 OS=Bos taurus OX=9913 GN=STK4 PE=2 SV=1 Length=487 Score = 231 bits (590), Expect = 7e-65, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 +K C R T L+ Sbjct 250 WSDSFMDFVKQCLVKSPEQRATATQLLQ 277 Score = 202 bits (515), Expect = 6e-55, Method: Composition-based stats. Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L + S + ++ L LG+G+ +VY+ + G Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K + + S+M Q H+ +G + + +V EY G + Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + Q L YL +H ++ NILL G Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163 Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D GV R + W+APE + + D W G T +E+ +G Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220 Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P P R PE QCL P QR + +L+ Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDSFMDFVKQCLVKSPEQRATATQLLQHPF 280 >sp|O18735|ERBB2_CANLF Receptor tyrosine-protein kinase erbB-2 OS=Canis lupus familiaris OX=9615 GN=ERBB2 PE=2 SV=1 Length=1259 Score = 244 bits (624), Expect = 7e-65, Method: Composition-based stats. Identities = 87/272 (32%), Positives = 133/272 (49%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + VA+K L+ + P+ E ++ + ++ + Sbjct 725 LGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRL 784 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C +QLV + +P G L D++ H +G LL + QI +GM+YL + Sbjct 785 LGICLTST---VQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLV 841 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ + VKI DFGLA+ + Y + G P+ W A E + +F + Sbjct 842 HRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHA-DGGKVPIKWMALESIPPRRFTH 900 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + + +LLE+GERLP+P C Sbjct 901 QSDVWSYGVTVWELMTFG--------------AKPYDGIPAREIPDLLEKGERLPQPPIC 946 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW ++ RP F L+ + Sbjct 947 TIDVYMIMVKCWMIDSECRPRFRELVAEFSRM 978 Score = 221 bits (562), Expect = 3e-57, Method: Composition-based stats. Identities = 64/316 (20%), Positives = 123/316 (39%), Gaps = 39/316 (12%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +P +Q + + E+ ++ LG G VY+G +G Sbjct 700 TPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENV-------------- 745 Query 630 GRDRGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ V +KVL + + A +M+ V +++ + G+C+ +VT+ Sbjct 746 ------KIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ-LVTQ 798 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 + +G L +R RG + + Q+A +SYLE+ LVH ++ RN+L+ Sbjct 799 LMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPN-- 856 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 +K++D G+ + I W+A E +P + D W +G Sbjct 857 -----HVKITDFGLARLLDIDETEYHADGGKVPIKWMALESIP--PRRFTHQSDVWSYGV 909 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQRPSFR 860 T+ E+ G P E ++ RLP+P + + +C + RP FR Sbjct 910 TVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFR 969 Query 861 TILRDLTRLQPHNLAD 876 ++ + +R+ Sbjct 970 ELVAEFSRMARDPQRF 985 >sp|O80623|Y2393_ARATH Probable receptor-like protein kinase At2g39360 OS=Arabidopsis thaliana OX=3702 GN=At2g39360 PE=1 SV=1 Length=815 Score = 239 bits (611), Expect = 7e-65, Method: Composition-based stats. Identities = 71/280 (25%), Positives = 125/280 (45%), Gaps = 17/280 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FGKV VAVK A Q + +K E+++L H H++ Sbjct 493 IGVGGFGKVYKGVLR-----DKTEVAVKR-GAPQSRQGLAEFKTEVEMLTQFRHRHLVSL 546 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA-- 1016 G C++ E + +V EY+ G+L+D+L + + Q L G+ YLH Sbjct 547 IGYCDENSE--MIIVYEYMEKGTLKDHLYDLDDKPRLSWRQRLEICVGAARGLHYLHTGS 604 Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + IHRD+ + N+LLD++ + K+ DFGL+K P+ + + V + PE L Sbjct 605 TRAIIHRDVKSANILLDDNFMAKVADFGLSKTGPDLDQTH-VSTAVKGSFGYLDPEYLTR 663 Query 1076 YKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + SDV+SFGV + E++ S P + + LI A + +L ++++ Sbjct 664 QQLTEKSDVYSFGVVMLEVVCGRPVIDPSLPREKVNLIEWAMKLVKKGKLEDIIDPFLVG 723 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + + + + C RP +L+ L+ + + Sbjct 724 KVKLEEVKKYCEVTEKCLSQNGIERPAMGDLLWNLEFMLQ 763 Score = 227 bits (579), Expect = 9e-61, Method: Composition-based stats. Identities = 64/321 (20%), Positives = 113/321 (35%), Gaps = 64/321 (20%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 L+ + + + +G G VY+G LR + Sbjct 476 PLALIKEATDDFDESLVIGVGGFGKVYKGVLRD-------------------------KT 510 Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 V +K P F +++Q H HL + G C E I+V EY+E G L Sbjct 511 EVAVKRGAPQSRQGLAEFKTEVEMLTQFRHRHLVSLIGYCDENSEMIIVYEYMEKGTLKD 570 Query 698 WLR--RERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTS 752 L ++ + ++ + A L YL + ++H +V NILL + Sbjct 571 HLYDLDDKPRLSWRQRLEICVGAARGLHYLHTGSTRAIIHRDVKSANILLD-------DN 623 Query 753 PFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 K++D G+ ++ +L PE L L+ D + FG +LE Sbjct 624 FMAKVADFGLSKTGPDLDQTHVSTAVKGSFGYLDPEYLT--RQQLTEKSDVYSFGVVMLE 681 Query 807 ICFDGEAPLQSRSPSEKEHFYQR------QHRLPEPSCPQL------------ATLTSQC 848 + G + P EK + + + +L + P L +T +C Sbjct 682 VVC-GRPVIDPSLPREKVNLIEWAMKLVKKGKLEDIIDPFLVGKVKLEEVKKYCEVTEKC 740 Query 849 LTYEPTQRPSFRTILRDLTRL 869 L+ +RP+ +L +L + Sbjct 741 LSQNGIERPAMGDLLWNLEFM 761 >sp|P27966|RMIL_AVEVR Serine/threonine-protein kinase-transforming protein Rmil OS=Avian rous-associated virus type 1 OX=11950 GN=V-RMIL PE=3 SV=1 Length=450 Score = 230 bits (587), Expect = 7e-65, Method: Composition-based stats. Identities = 76/306 (25%), Positives = 130/306 (42%), Gaps = 31/306 (10%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 + + +SD + + +G G FG V + VAVK L Sbjct 61 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-------DVAVKMLNV 113 Query 935 DC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991 PQ +K E+ +LR H +I+ + G + L +V ++ SL +L Sbjct 114 TAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY---STKPQLAIVTQWCEGSSLYHHLHII 170 Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 + +L+ A+Q +GM YLHA+ IHRDL + N+ L D VKIGDFGLA Sbjct 171 ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRW 230 Query 1052 HEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQ--SPPT 1106 ++ E + W APE ++ + + + SDV++FG+ LYEL+T + Sbjct 231 SGSHQF-EQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRD 289 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + + ++G + ++ CP + LM C + + RP F ++ Sbjct 290 QIIFMVGRGYLSPDLSKVR------------SNCPKAMKRLMAECLKKKRDERPLFPQIL 337 Query 1167 PILKTV 1172 ++ + Sbjct 338 ASIELL 343 Score = 223 bits (569), Expect = 2e-62, Method: Composition-based stats. Identities = 71/379 (19%), Positives = 130/379 (34%), Gaps = 57/379 (15%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSF-HRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 P P R +TL S + +IT +G G+ VY+G+ + Sbjct 46 PGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD 105 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSHTH 669 V +K+L+ + AF ++ + H + Sbjct 106 ---------------------------VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVN 138 Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729 + G + P+ +VT++ E L L M + +A+Q A + YL K+ Sbjct 139 ILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKS 197 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPEC 783 ++H ++ NI L +K+ D G+ G+ E+ I W+APE Sbjct 198 IIHRDLKSNNIFLHE-------DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEV 250 Query 784 LPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP------ 836 + N S D + FG L E+ G+ P + + ++ F + L Sbjct 251 IRMQDKNPYSFQSDVYAFGIVLYELM-TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRS 309 Query 837 SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL----TRLQPHNLADVLTVNPDSPASDPTV 891 +CP+ + L ++CL + +RP F IL + L + + + Sbjct 310 NCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDF 369 Query 892 FHKRYLKKIRDLGEGHFGK 910 + G G+ Sbjct 370 SLYACASPKTPIQAGGIGE 388 >sp|Q39202|RLK1_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase RLK1 OS=Arabidopsis thaliana OX=3702 GN=RLK1 PE=2 SV=2 Length=832 Score = 240 bits (612), Expect = 8e-65, Method: Composition-based stats. Identities = 74/289 (26%), Positives = 122/289 (42%), Gaps = 12/289 (4%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +LG G FG V Y G+ VAVK L + +K E+ ++ ++H+++++ Sbjct 536 ELGRGAFGIVYKG-YLEVAGGSEVTVAVKKLDR-LDLDNEKEFKNEVKVIGQIHHKNLVR 593 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLH---AQ 1017 G C + + +V E++P G+L ++L R A I G+ YLH ++ Sbjct 594 LIGFCNEGQSQ--MIVYEFLPQGTLANFLFRRPRPSWEDRKNIAVAIARGILYLHEECSE 651 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IH D+ +N+LLD +I DFGLAK + Y + + APE + Sbjct 652 QIIHCDIKPQNILLDEYYTPRISDFGLAKLLLMNQTY--TLTNIRGTKGYVAPEWFRNSP 709 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 DV+S+GV L E++ C + LI A RL +L E Sbjct 710 ITSKVDVYSYGVMLLEIV--CCKKAVDLEDNVILINWAYDCFRQGRLEDLTEDDSEAMND 767 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 + + C + E RP N+ +L+ V + + PS +S Sbjct 768 METVERYVKIAIWCIQEEHGMRPNMRNVTQMLEGVIQVFDPPNPSPYST 816 Score = 226 bits (575), Expect = 4e-60, Method: Composition-based stats. Identities = 80/432 (19%), Positives = 150/432 (35%), Gaps = 67/432 (16%) Query 482 RLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAG 541 + L+ +RS D +++R I G + L A L + Sbjct 424 KFPLSHGERSPRGDSDTFIKVRNRSIADVP------VTGNRAKKLDWLIIACSVLLGTSA 477 Query 542 DDCFSLRRCCLPQPGETSNLIIMRG-------ARASPRTLNLSQLSFHRVDQKEITQLSH 594 F C + ++ N++ + A + LNL ++ + + Sbjct 478 FVIFD-TSCSYRKTKKSKNMMKNQARDIGRTTATTTANELNLRVFTYGELAEATRDFTEE 536 Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LG+G VY+G L V G G E+ V +K LD D Sbjct 537 LGRGAFGIVYKGYLEVAG---------------------GSEVTVAVKKLDRLDLDNEKE 575 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 F ++ Q+ H +L + G C G ++V E++ G L +L R R + + Sbjct 576 FKNEVKVIGQIHHKNLVRLIGFCNEGQSQMIVYEFLPQGTLANFLFR-RPRPSWEDRKNI 634 Query 715 AQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771 A +A + YL ++ ++H ++ +NILL ++SD G+ L + Sbjct 635 AVAIARGILYLHEECSEQIIHCDIKPQNILLDEYYTP-------RISDFGLAKLLLMNQT 687 Query 772 RV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP--SEKE 824 ++APE + +++ +D + +G LLEI +A + Sbjct 688 YTLTNIRGTKGYVAPEWFRN--SPITSKVDVYSYGVMLLEIVCCKKAVDLEDNVILINWA 745 Query 825 HFYQRQHRLPE------------PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 + RQ RL + + + + C+ E RP+ R + + L + Sbjct 746 YDCFRQGRLEDLTEDDSEAMNDMETVERYVKIAIWCIQEEHGMRPNMRNVTQMLEGVIQV 805 Query 873 NLADVLTVNPDS 884 + Sbjct 806 FDPPNPSPYSTF 817 >sp|P43298|TMK1_ARATH Receptor protein kinase TMK1 OS=Arabidopsis thaliana OX=3702 GN=TMK1 PE=1 SV=1 Length=942 Score = 241 bits (616), Expect = 8e-65, Method: Composition-based stats. Identities = 82/291 (28%), Positives = 124/291 (43%), Gaps = 23/291 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961 LG G FG V G +AVK ++ + + +K EI +L + H H++ Sbjct 594 LGSGGFGVVYKGEL-----HDGTKIAVKRMENGVIAGKGFAEFKSEIAVLTKVRHRHLVT 648 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR------HSIGLAQLLLFAQQICEGMAYLH 1015 G C D EK LV EY+P G+L +L + Q L A + G+ YLH Sbjct 649 LLGYCLDGNEK--LLVYEYMPQGTLSRHLFEWSEEGLKPLLWKQRLTLALDVARGVEYLH 706 Query 1016 ---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Q +IHRDL N+LL +D K+ DFGL + PEG R G + APE Sbjct 707 GLAHQSFIHRDLKPSNILLGDDMRAKVADFGLVRLAPEGKGSIETRIAG--TFGYLAPEY 764 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + DV+SFGV L EL+T S +S P + + L+ + + Sbjct 765 AVTGRVTTKVDVYSFGVILMELITGRKSLDESQPEESIHLVSWFKRMYINKEASFKKAID 824 Query 1132 ERLPRPDKCPCEVY---HLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 + ++ V+ L +C E RP + + IL ++ E ++ Sbjct 825 TTIDLDEETLASVHTVAELAGHCCAREPYQRPDMGHAVNILSSLVELWKPS 875 Score = 216 bits (550), Expect = 2e-56, Method: Composition-based stats. Identities = 66/309 (21%), Positives = 110/309 (36%), Gaps = 70/309 (23%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + + LG G VY+G L ++ +K ++ Sbjct 585 TNNFSSDNILGSGGFGVVYKGELHDG-------------------------TKIAVKRME 619 Query 646 PS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--R 701 F +++++V H HL + G C+ G E ++V EY+ G L L Sbjct 620 NGVIAGKGFAEFKSEIAVLTKVRHRHLVTLLGYCLDGNEKLLVYEYMPQGTLSRHLFEWS 679 Query 702 ERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 E G P+ W ++ +A +A + YL +++ +H ++ NILL G K Sbjct 680 EEGLKPLLWKQRLTLALDVARGVEYLHGLAHQSFIHRDLKPSNILL-------GDDMRAK 732 Query 757 LSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ A + + +LAPE G ++T +D + FG L+E+ G Sbjct 733 VADFGLVRLAPEGKGSIETRIAGTFGYLAPEYAVTG--RVTTKVDVYSFGVILMELI-TG 789 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPS---------------------CPQLATLTSQCLT 850 L P E H R+ +A L C Sbjct 790 RKSLDESQPEESIHLVSWFKRMYINKEASFKKAIDTTIDLDEETLASVHTVAELAGHCCA 849 Query 851 YEPTQRPSF 859 EP QRP Sbjct 850 REPYQRPDM 858 >sp|C0LGG6|Y5189_ARATH Probable LRR receptor-like protein kinase At1g51890 OS=Arabidopsis thaliana OX=3702 GN=At1g51890 PE=1 SV=2 Length=876 Score = 240 bits (613), Expect = 8e-65, Method: Composition-based stats. Identities = 72/291 (25%), Positives = 124/291 (43%), Gaps = 23/291 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V D T VAVK L Q +K E+++L ++H H++ Sbjct 576 LGKGGFGTVYHGNLDDT------QVAVKMLSH-SSAQGYKEFKAEVELLLRVHHRHLVGL 628 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGMAYLHA-- 1016 G C+D +L L+ EY+ G LR+ + + + + A + +G+ YLH Sbjct 629 VGYCDDGD--NLALIYEYMEKGDLRENMSGKHSVNVLSWETRMQIAVEAAQGLEYLHNGC 686 Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRD+ N+LL+ K+ DFGL+++ P E + + +P + PE + Sbjct 687 RPPMVHRDVKPTNILLNERSQAKLADFGLSRSFPVDGESHVMTVVAGTP-GYLDPEYYRT 745 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 SDV+SFGV L E++T+ + + + +T + +++ Sbjct 746 NWLSEKSDVYSFGVVLLEIVTN-QPVMNKNRERPHINEWVMFMLTNGDIKSIVDPKLNED 804 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK-----TVHEKYQGQAP 1181 +V L C +S RPT +++ L + K QA Sbjct 805 YDTNGVWKVVELALACVNPSSSRRPTMPHVVMELNECLALEIERKQGSQAT 855 Score = 209 bits (533), Expect = 1e-54, Method: Composition-based stats. Identities = 71/319 (22%), Positives = 113/319 (35%), Gaps = 61/319 (19%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 + ++ V + LG+G VY G L + Sbjct 558 RKFTYSEVLKMTKNFERVLGKGGFGTVYHGNL--------------------------DD 591 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +V +K+L S F L+ +V H HL + G C G ++ EY+E G L Sbjct 592 TQVAVKMLSHSSAQGYKEFKAEVELLLRVHHRHLVGLVGYCDDGDNLALIYEYMEKGDLR 651 Query 697 VWLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT 751 + + ++W +M +A + A L YL N +VH +V NILL A Sbjct 652 ENMSGKHSVNVLSWETRMQIAVEAAQGLEYLHNGCRPPMVHRDVKPTNILLNERSQA--- 708 Query 752 SPFIKLSDPGVGLG-ALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 KL+D G+ + E V +L PE N LS D + FG LL Sbjct 709 ----KLADFGLSRSFPVDGESHVMTVVAGTPGYLDPEYYRT--NWLSEKSDVYSFGVVLL 762 Query 806 EICFDGEAPLQSR---SPSEKEHFYQRQHRLPEPSCPQL------------ATLTSQCLT 850 EI + ++R +E F + P+L L C+ Sbjct 763 EIVTNQPVMNKNRERPHINEWVMFMLTNGDIKSIVDPKLNEDYDTNGVWKVVELALACVN 822 Query 851 YEPTQRPSFRTILRDLTRL 869 ++RP+ ++ +L Sbjct 823 PSSSRRPTMPHVVMELNEC 841 >sp|Q9S9M5|WAKLA_ARATH Wall-associated receptor kinase-like 1 OS=Arabidopsis thaliana OX=3702 GN=WAKL1 PE=2 SV=1 Length=730 Score = 238 bits (606), Expect = 8e-65, Method: Composition-based stats. Identities = 72/292 (25%), Positives = 117/292 (40%), Gaps = 23/292 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G G V G +VAVK K + EI +L + H +I+K Sbjct 435 LGQGGQGTVYKGML-----VDGSIVAVKRSKV-VDEDKMEEFINEIVLLSQINHRNIVKL 488 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQ- 1017 GCC + E + LV EY+P G L L S + L A +I + Y+H+ Sbjct 489 LGCCLE-TEVPI-LVYEYIPNGDLFKRLHDESDDYTMTWEVRLRIAIEIAGALTYMHSAA 546 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 HRD+ N+LLD K+ DFG +++V + + + PE Sbjct 547 SFPIFHRDIKTTNILLDEKYRAKVSDFGTSRSVTLDQTH--LTTLVAGTFGYMDPEYFLS 604 Query 1076 YKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 ++ + SDV+SFGV L EL+T S+ + L M R+ ++++ + Sbjct 605 SQYTHKSDVYSFGVVLVELITGEKPLSRVRSEEGRGLATHFLEAMKENRVIDIIDIRIKD 664 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 + V L + C + RP + + L+ + +P V Sbjct 665 ESKLEQVMAVAKLARKCLNRKGKNRPNMKEVSNELERIR-----SSPEDLDV 711 Score = 225 bits (573), Expect = 2e-60, Method: Composition-based stats. Identities = 64/314 (20%), Positives = 113/314 (36%), Gaps = 63/314 (20%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + LGQG + VY+G L V +K Sbjct 425 ATDNFSIDRVLGQGGQGTVYKGMLVDGSI-------------------------VAVKRS 459 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D F L+SQ++H ++ + G C+ I+V EY+ +G L L E Sbjct 460 KVVDEDKMEEFINEIVLLSQINHRNIVKLLGCCLETEVPILVYEYIPNGDLFKRLHDESD 519 Query 705 HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 M W ++ +A ++A AL+Y+ + + H ++ NILL A K+SD Sbjct 520 DYTMTWEVRLRIAIEIAGALTYMHSAASFPIFHRDIKTTNILLDEKYRA-------KVSD 572 Query 760 PGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G + ++ PE ++ + D + FG L+E+ GE P Sbjct 573 FGTSRSVTLDQTHLTTLVAGTFGYMDPEYFL--SSQYTHKSDVYSFGVVLVELI-TGEKP 629 Query 815 LQSRSPSEKEHF------YQRQHRLPEP------------SCPQLATLTSQCLTYEPTQR 856 L E +++R+ + +A L +CL + R Sbjct 630 LSRVRSEEGRGLATHFLEAMKENRVIDIIDIRIKDESKLEQVMAVAKLARKCLNRKGKNR 689 Query 857 PSFRTILRDLTRLQ 870 P+ + + +L R++ Sbjct 690 PNMKEVSNELERIR 703 >sp|Q9LFV3|CRLK2_ARATH Calcium/calmodulin-regulated receptor-like kinase 2 OS=Arabidopsis thaliana OX=3702 GN=CRLK2 PE=2 SV=1 Length=436 Score = 229 bits (585), Expect = 9e-65, Method: Composition-based stats. Identities = 74/314 (24%), Positives = 124/314 (39%), Gaps = 30/314 (10%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 P + K LG+G FG V GE+ A K Q + Sbjct 102 PRYNYKDIQKATQNFTTVLGQGSFGPVYKAV-----MPNGELAAAKV-HGSNSSQGDREF 155 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQL 1000 + E+ +L L+H +++ G C D+ + L+ E++ GSL + L + + Sbjct 156 QTEVSLLGRLHHRNLVNLTGYCVDKSHR--MLIYEFMSNGSLENLLYGGEGMQVLNWEER 213 Query 1001 LLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 L A I G+ YLH IHRDL + N+LLD+ K+ DFGL+K + R+ Sbjct 214 LQIALDISHGIEYLHEGAVPPVIHRDLKSANILLDHSMRAKVADFGLSKEMVLD----RM 269 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 + P + K+ SD++SFGV + EL+T P +E I +A Sbjct 270 TSGLKGTHGYMDPTYISTNKYTMKSDIYSFGVIILELITAI----HPQQNLMEYINLA-- 323 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE--- 1174 M+ + E+L++ + + + C RP+ + + + + Sbjct 324 SMSPDGIDEILDQKLVGNASIEEVRLLAKIANRCVHKTPRKRPSIGEVTQFILKIKQSRS 383 Query 1175 --KYQGQAPSVFSV 1186 + Q S F V Sbjct 384 RGRRQDTMSSSFGV 397 Score = 206 bits (524), Expect = 1e-56, Method: Composition-based stats. Identities = 56/373 (15%), Positives = 117/373 (31%), Gaps = 55/373 (15%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 + + ++ + + + LGQG+ VY+ + Sbjct 97 SASGIPRYNYKDIQKATQNFTTVLGQGSFGPVYKAVMPNGE------------------- 137 Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 KV + F SL+ ++ H +L + G CV +++ E++ Sbjct 138 ------LAAAKVHGSNSSQGDREFQTEVSLLGRLHHRNLVNLTGYCVDKSHRMLIYEFMS 191 Query 692 HGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLG 746 +G L+ L G + W ++ +A ++ + YL ++H ++ NILL Sbjct 192 NGSLENLLYGGEGMQVLNWEERLQIALDISHGIEYLHEGAVPPVIHRDLKSANILLDH-- 249 Query 747 LAEGTSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 S K++D G+ + ++ P + N + D + FG Sbjct 250 -----SMRAKVADFGLSKEMVLDRMTSGLKGTHGYMDPTYIST--NKYTMKSDIYSFGVI 302 Query 804 LLEICFDGEAPLQ--------SRSPSEKEHFYQRQ--HRLPEPSCPQLATLTSQCLTYEP 853 +LE+ S SP + ++ LA + ++C+ P Sbjct 303 ILELITAIHPQQNLMEYINLASMSPDGIDEILDQKLVGNASIEEVRLLAKIANRCVHKTP 362 Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE---GHFGK 910 +RPS + + + +++ S + G Sbjct 363 RKRPSIGEVTQFILKIKQSRSRGRRQDTMSSSFGVGYEEDLSRVMSRIKDQHVELGLLAG 422 Query 911 VSLYCYDPTNDGT 923 V + N T Sbjct 423 VKEENHQERNIAT 435 >sp|Q9LEU7|CIPK5_ARATH CBL-interacting serine/threonine-protein kinase 5 OS=Arabidopsis thaliana OX=3702 GN=CIPK5 PE=1 SV=1 Length=445 Score = 230 bits (586), Expect = 9e-65, Method: Composition-based stats. Identities = 67/270 (25%), Positives = 110/270 (41%), Gaps = 27/270 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD---CGPQHRSGWKQEIDILRTLYHEHI 959 LG+G F KV GE VA+K + D P K+EI I++ + H +I Sbjct 18 LGKGTFAKVYYG----KEIIGGECVAIKVINKDQVMKRPGMMEQIKREISIMKLVRHPNI 73 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 ++ K + + + VME+V G L + + + + QQ+ + Y H++ Sbjct 74 VELKEVMATKTK--IFFVMEFVKGGELFCKISKGKLHEDAARRYFQQLISAVDYCHSRGV 131 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 HRDL N+LLD + +KI DFGL+ + + + +P + APE LK+ + Sbjct 132 SHRDLKPENLLLDENGDLKISDFGLSALPEQILQDGLLHTQCGTPA-YVAPEVLKKKGYD 190 Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 +D+WS GV LY LL C Q + M + R + P Sbjct 191 GAKADIWSCGVVLYVLLAGCLPFQD------------ENLMNMYRKIFRAD----FEFPP 234 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 E L+ + R + ++ Sbjct 235 WFSPEARRLISKLLVVDPDRRISIPAIMRT 264 Score = 186 bits (471), Expect = 2e-49, Method: Composition-based stats. Identities = 57/332 (17%), Positives = 104/332 (31%), Gaps = 44/332 (13%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 RV + LG+GT VY G+ + G V +K Sbjct 6 RVLFGKYEMGRLLGKGTFAKVYYGKEIIGGEC------------------------VAIK 41 Query 643 VLDPSH----HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V++ + S+M V H ++ + V + V E+V+ G L + Sbjct 42 VINKDQVMKRPGMMEQIKREISIMKLVRHPNIVELKEVMATKTKIFFVMEFVKGGEL--F 99 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + +G + QQL SA+ Y ++ + H ++ N+LL G +K+S Sbjct 100 CKISKGKLHEDAARRYFQQLISAVDYCHSRGVSHRDLKPENLLLDENGD-------LKIS 152 Query 759 DPGVGLGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 D G+ + ++APE L D W G L + Sbjct 153 DFGLSALPEQILQDGLLHTQCGTPAYVAPEVLKKKGYD-GAKADIWSCGVVLYVLLAGCL 211 Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 + ++ P P+ L S+ L +P +R S I+R + Sbjct 212 PFQDENLMNMYRKIFRADFEFPPWFSPEARRLISKLLVVDPDRRISIPAIMRTPWLRKNF 271 Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 ++ + + + Sbjct 272 TPPLAFKIDEPICSQSSKNNEEEEEDGDCENQ 303 >sp|A8R7E6|CERK1_ARATH Chitin elicitor receptor kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CERK1 PE=1 SV=1 Length=617 Score = 235 bits (599), Expect = 9e-65, Method: Composition-based stats. Identities = 69/291 (24%), Positives = 117/291 (40%), Gaps = 30/291 (10%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 +G+G FG V GE A+K + + Q + E+ +L + Sbjct 320 DNFNLSFKIGQGGFGAVYYAELR------GEKAAIKKMDMEASKQ----FLAELKVLTRV 369 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGM 1011 +H ++++ G C E SL LV EYV G+L +L R + + + A G+ Sbjct 370 HHVNLVRLIGYCV---EGSLFLVYEYVENGNLGQHLHGSGREPLPWTKRVQIALDSARGL 426 Query 1012 AYLHAQHY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 Y+H +HRD+ + N+L+D K+ DFGL K G R + Sbjct 427 EYIHEHTVPVYVHRDIKSANILIDQKFRAKVADFGLTKLTEVGGSATR---GAMGTFGYM 483 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR----- 1123 APE + + DV++FGV LYEL++ + E G+ + Sbjct 484 APETV-YGEVSAKVDVYAFGVVLYELISAKGAVVKMTEAVGEFRGLVGVFEESFKETDKE 542 Query 1124 --LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 L ++++ P ++ L K C + A RP+ ++ L T+ Sbjct 543 EALRKIIDPRLGDSYPFDSVYKMAELGKACTQENAQLRPSMRYIVVALSTL 593 Score = 198 bits (504), Expect = 2e-52, Method: Composition-based stats. Identities = 52/233 (22%), Positives = 88/233 (38%), Gaps = 48/233 (21%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +GQG VY LR E + +K + Sbjct 318 ATDNFNLSFKIGQGGFGAVYYAELRGE--------------------------KAAIKKM 351 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-R 703 D + + F ++++V H +L + G CV G +V EYVE+G L L R Sbjct 352 D---MEASKQFLAELKVLTRVHHVNLVRLIGYCVEGS-LFLVYEYVENGNLGQHLHGSGR 407 Query 704 GHVPMAWKMVVAQQLASALSYLENKNL---VHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 +P ++ +A A L Y+ + VH ++ NIL+ + A K++D Sbjct 408 EPLPWTKRVQIALDSARGLEYIHEHTVPVYVHRDIKSANILIDQKFRA-------KVADF 460 Query 761 GVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 G+ G + + ++APE + G +S +D + FG L E+ Sbjct 461 GLTKLTEVGGSATRGAMGTFGYMAPETVYG---EVSAKVDVYAFGVVLYELIS 510 >sp|Q9FX99|Y1497_ARATH Probable receptor-like protein kinase At1g49730 OS=Arabidopsis thaliana OX=3702 GN=At1g49730 PE=2 SV=1 Length=663 Score = 236 bits (602), Expect = 9e-65, Method: Composition-based stats. Identities = 69/301 (23%), Positives = 120/301 (40%), Gaps = 15/301 (5%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935 + +G+G FG V + G + AVK + Sbjct 306 HEDDSSSAFRKFSYKEMTNATNDFNTVIGQGGFGTVYKAEF-----NDGLIAAVKKMNK- 359 Query 936 CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---R 992 Q + +EI +L L+H +++ KG C ++ E+ LV +Y+ GSL+D+L + Sbjct 360 VSEQAEQDFCREIGLLAKLHHRNLVALKGFCINKKER--FLVYDYMKNGSLKDHLHAIGK 417 Query 993 HSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 + A + + YLH HRD+ + N+LLD + + K+ DFGLA + Sbjct 418 PPPSWGTRMKIAIDVANALEYLHFYCDPPLCHRDIKSSNILLDENFVAKLSDFGLAHSSR 477 Query 1050 EGHEYYR-VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 +G + V D + PE + + SDV+S+GV L EL+T + Sbjct 478 DGSVCFEPVNTDIRGTPGYVDPEYVVTQELTEKSDVYSYGVVLLELITGRRAVDEGRNLV 537 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 + L L + + K V +++ C E E RP+ + ++ + Sbjct 538 EMSQRFLLAKSKHLELVDPRIKDSINDAGGKQLDAVVTVVRLCTEKEGRSRPSIKQVLRL 597 Query 1169 L 1169 L Sbjct 598 L 598 Score = 211 bits (537), Expect = 3e-56, Method: Composition-based stats. Identities = 57/322 (18%), Positives = 108/322 (34%), Gaps = 62/322 (19%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 + + S+ + + +GQG VY+ Sbjct 307 EDDSSSAFRKFSYKEMTNATNDFNTVIGQGGFGTVYKA---------------------- 344 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 + L +K ++ F L++++ H +L + G C+ E +V + Sbjct 345 ---EFNDGLIAAVKKMNKVSEQAEQDFCREIGLLAKLHHRNLVALKGFCINKKERFLVYD 401 Query 689 YVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLAR 744 Y+++G L L + +M +A +A+AL YL + L H ++ NILL Sbjct 402 YMKNGSLKDHLHAIGKPPPSWGTRMKIAIDVANALEYLHFYCDPPLCHRDIKSSNILLDE 461 Query 745 LGLAEGTSPFIKLSDPGVGLGALS--------REERVERIPWLAPECLPGGANSLSTAMD 796 + KLSD G+ + + ++ PE + L+ D Sbjct 462 -------NFVAKLSDFGLAHSSRDGSVCFEPVNTDIRGTPGYVDPEYVVT--QELTEKSD 512 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEK---------EHFYQRQHRLPE-------PSCPQ 840 + +G LLE+ A + R+ E +H R+ + Sbjct 513 VYSYGVVLLELITGRRAVDEGRNLVEMSQRFLLAKSKHLELVDPRIKDSINDAGGKQLDA 572 Query 841 LATLTSQCLTYEPTQRPSFRTI 862 + T+ C E RPS + + Sbjct 573 VVTVVRLCTEKEGRSRPSIKQV 594 >sp|O80719|Y2706_ARATH Probable receptor-like protein kinase At2g47060 OS=Arabidopsis thaliana OX=3702 GN=At2g47060 PE=1 SV=1 Length=365 Score = 227 bits (579), Expect = 9e-65, Method: Composition-based stats. Identities = 71/284 (25%), Positives = 118/284 (42%), Gaps = 24/284 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG +G+V + A+K L D Q + + ++ ++ L H++ ++ Sbjct 79 IGEGSYGRVYYGVLNNDLPS-----AIKKL--DSNKQPDNEFLAQVSMVSRLKHDNFVQL 131 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------IGLAQLLLFAQQICEGMA 1012 G C D + L E+ GSL D L + Q + A G+ Sbjct 132 LGYCVDGNSRILS--YEFANNGSLHDILHGRKGVKGAQPGPVLSWYQRVKIAVGAARGLE 189 Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH + H IHRD+ + NVLL D + KI DF L+ P+ ++A Sbjct 190 YLHEKANPHIIHRDIKSSNVLLFEDDVAKIADFDLSNQAPD-MAARLHSTRVLGTFGYHA 248 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVLRLTELL 1128 PE + SDV+SFGV L ELLT P L+ A +++ ++ + + Sbjct 249 PEYAMTGQLNAKSDVYSFGVVLLELLTGRKPVDHRLPRGQQSLVTWATPKLSEDKVKQCV 308 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + P K ++ + C + EA FRP ++ L+ + Sbjct 309 DARLGGDYPPKAVAKLAAVAALCVQYEADFRPNMSIVVKALQPL 352 Score = 204 bits (519), Expect = 9e-57, Method: Composition-based stats. Identities = 56/279 (20%), Positives = 99/279 (35%), Gaps = 53/279 (19%) Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 + P + + S + + S +G+G+ VY G L Sbjct 52 KLQPIEVPIIPFSELKEATDDFGSNSLIGEGSYGRVYYGVL------------------- 92 Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 +L +K LD + F S++S++ H + + G CV G I+ Sbjct 93 ------NNDLPSAIKKLDSN-KQPDNEFLAQVSMVSRLKHDNFVQLLGYCVDGNSRILSY 145 Query 688 EYVEHGPLDVWLRRERG--------HVPMAWKMVVAQQLASALSYLENK---NLVHGNVC 736 E+ +G L L +G + ++ +A A L YL K +++H ++ Sbjct 146 EFANNGSLHDILHGRKGVKGAQPGPVLSWYQRVKIAVGAARGLEYLHEKANPHIIHRDIK 205 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVG------LGALSREERVERIPWLAPECLPGGANS 790 N+LL +A K++D + L + + APE G Sbjct 206 SSNVLLFEDDVA-------KIADFDLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTG--Q 256 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 L+ D + FG LLE+ G P+ R P ++ Sbjct 257 LNAKSDVYSFGVVLLELL-TGRKPVDHRLPRGQQSLVTW 294 >sp|Q1PEM5|PERK3_ARATH Proline-rich receptor-like protein kinase PERK3 OS=Arabidopsis thaliana OX=3702 GN=PERK3 PE=2 SV=2 Length=513 Score = 232 bits (591), Expect = 9e-65, Method: Composition-based stats. Identities = 73/279 (26%), Positives = 116/279 (42%), Gaps = 21/279 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG V G VAVK LK Q ++ E++I+ ++H +++ Sbjct 189 LGEGGFGFVYKGIL-----NNGNEVAVKQLKVG-SAQGEKEFQAEVNIISQIHHRNLVSL 242 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 G C ++ LV E+VP +L +L R ++ + L A +G++YLH Sbjct 243 VGYCIAGAQR--LLVYEFVPNNTLEFHLHGKGRPTMEWSLRLKIAVSSSKGLSYLHENCN 300 Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ A N+L+D K+ DFGLAK + + + R + APE Sbjct 301 PKIIHRDIKAANILIDFKFEAKVADFGLAKIALDTNTHVSTR--VMGTFGYLAPEYAASG 358 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQG----QMTVLRLTELLERG 1131 K SDV+SFGV L EL+T + L+ A+ + L + Sbjct 359 KLTEKSDVYSFGVVLLELITGRRPVDANNVYADDSLVDWARPLLVQALEESNFEGLADIK 418 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + + C A RP + ++ +L+ Sbjct 419 LNNEYDREEMARMVACAAACVRYTARRRPRMDQVVRVLE 457 Score = 225 bits (573), Expect = 2e-62, Method: Composition-based stats. Identities = 66/334 (20%), Positives = 116/334 (35%), Gaps = 50/334 (15%) Query 513 AFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI--IMRGARAS 570 F L S S + G + F L C +P + L I Sbjct 110 GFSLSPPSPSRLSTGAVVGISIGGGVFVLTLIFFL--CKKKRPRDDKALPAPIGLVLGIH 167 Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 T +L+ + ++ + LG+G VY+G L Sbjct 168 QSTFTYGELA---RATNKFSEANLLGEGGFGFVYKGILNNGN------------------ 206 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 V +K L F +++SQ+ H +L + G C+ G + ++V E+V Sbjct 207 -------EVAVKQLKVGSAQGEKEFQAEVNIISQIHHRNLVSLVGYCIAGAQRLLVYEFV 259 Query 691 EHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLG 746 + L+ L + R + + ++ +A + LSYL ++H ++ NIL+ Sbjct 260 PNNTLEFHLHGKGRPTMEWSLRLKIAVSSSKGLSYLHENCNPKIIHRDIKAANILIDFKF 319 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFG 801 A K++D G+ AL V +LAPE G L+ D + FG Sbjct 320 EA-------KVADFGLAKIALDTNTHVSTRVMGTFGYLAPEYAASG--KLTEKSDVYSFG 370 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 LLE+ + ++ + L + Sbjct 371 VVLLELITGRRPVDANNVYADDSLVDWARPLLVQ 404 >sp|Q86AE1|Y9853_DICDI Probable serine/threonine-protein kinase DDB_G0271538 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0271538 PE=3 SV=1 Length=527 Score = 232 bits (592), Expect = 1e-64, Method: Composition-based stats. Identities = 76/293 (26%), Positives = 123/293 (42%), Gaps = 32/293 (11%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK--ADCGPQHRSGWKQEIDILRTLY 955 ++G G FG+V Y T+ VAVK L P + +EI IL+ + Sbjct 34 FMDVEIGRGSFGQVQKASYFGTD------VAVKQLSTLVSIDPDYFKFMLREIKILKGMR 87 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMA 1012 H +I++Y G C +G +V EY+ G L ++ +I + A I + Sbjct 88 HPNIVQYIGACCHEG--RYMIVTEYIKGGDLHQFIKARGVSNISWTLRMKLALDIASAFS 145 Query 1013 YLHAQHYIHRDLAARNVLLDNDR----LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 YLH++ I RDL A+N+L+D K+ DFG A+ +G + + G Sbjct 146 YLHSKKVIFRDLKAKNILVDEIGDGLYRAKVIDFGFARIF-DGKDTNNLTICGSENT--M 202 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 +PE + + + DV+S+GV L EL+ ++ + + L Sbjct 203 SPEVIVGSSYNDSCDVYSYGVLLLELICGSRVVKTQLKR-----------TPMNAFDMNL 251 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 E+ E L P+ CP L K C RPTF+ ++ LK + + P Sbjct 252 EKAEHLA-PESCPRAFMDLAKWCCSYNPKDRPTFKIVVEGLKVLTNQQLKDLP 303 Score = 201 bits (512), Expect = 4e-54, Method: Composition-based stats. Identities = 57/306 (19%), Positives = 111/306 (36%), Gaps = 43/306 (14%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 F +D ++ +G+G+ V + V Sbjct 24 DFSSLDYSDLFMDVEIGRGSFGQVQKASYFGTD--------------------------V 57 Query 640 VLKVLD---PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +K L D ++ + H ++ G C ++VTEY++ G L Sbjct 58 AVKQLSTLVSIDPDYFKFMLREIKILKGMRHPNIVQYIGACCHEGRYMIVTEYIKGGDLH 117 Query 697 VWLR-RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +++ R ++ +M +A +ASA SYL +K ++ ++ +NIL+ +G Sbjct 118 QFIKARGVSNISWTLRMKLALDIASAFSYLHSKKVIFRDLKAKNILVDEIG---DGLYRA 174 Query 756 KLSDPGVGLGALSREERVERIPW----LAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 K+ D G ++ I ++PE + G +S + + D + +G LLE+ Sbjct 175 KVIDFGFARIFDGKDTNNLTICGSENTMSPEVIVG--SSYNDSCDVYSYGVLLLELICGS 232 Query 812 EAPLQSRS----PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + + + +H PE L C +Y P RP+F+ ++ L Sbjct 233 RVVKTQLKRTPMNAFDMNLEKAEHLAPESCPRAFMDLAKWCCSYNPKDRPTFKIVVEGLK 292 Query 868 RLQPHN 873 L Sbjct 293 VLTNQQ 298 >sp|O43283|M3K13_HUMAN Mitogen-activated protein kinase kinase kinase 13 OS=Homo sapiens OX=9606 GN=MAP3K13 PE=1 SV=1 Length=966 Score = 241 bits (616), Expect = 1e-64, Method: Composition-based stats. Identities = 83/301 (28%), Positives = 122/301 (41%), Gaps = 35/301 (12%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + + + + D + +++ LG G G V L + E VA+K Sbjct 142 WNIIGKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRA------EEVAIK 195 Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 ++ I LR L H +II +KG C ++MEY G L + L Sbjct 196 KVREQNETD--------IKHLRKLKHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVL 245 Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 I L+ ++ I GM YLH IHRDL + NVL+ + VKI DFG +K + Sbjct 246 RAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELS 305 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 + + V W APE ++ D+WSFGV L+ELLT P K + Sbjct 306 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG-----EIPYKDV 356 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + I G + LP P CP LMK W+++ RP+F + L Sbjct 357 DSSAIIWGVGSN---------SLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHL 407 Query 1170 K 1170 Sbjct 408 D 408 Score = 214 bits (546), Expect = 6e-56, Method: Composition-based stats. Identities = 65/305 (21%), Positives = 109/305 (36%), Gaps = 50/305 (16%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 +A L Q V +EI++L LG G + V+ G+ R E Sbjct 146 GKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAE--------------- 190 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 V +K + + + ++ H ++ GVC + P ++ Sbjct 191 -----------EVAIKKVREQNE-------TDIKHLRKLKHPNIIAFKGVCTQAPCYCII 232 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 EY HG L LR R + + + +AS ++YL ++H ++ N+L+ Sbjct 233 MEYCAHGQLYEVLRAGR-KITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTD 291 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +K+SD G + ++ + W+APE + +S +D W FG Sbjct 292 A-------VKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 342 Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 L E+ GE P + S +P L Q +P RPSFR Sbjct 343 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFR 401 Query 861 TILRD 865 L Sbjct 402 QTLMH 406 >sp|Q9LIG2|RLK6_ARATH Receptor-like protein kinase At3g21340 OS=Arabidopsis thaliana OX=3702 GN=At3g21340 PE=1 SV=1 Length=899 Score = 240 bits (613), Expect = 1e-64, Method: Composition-based stats. Identities = 65/295 (22%), Positives = 122/295 (41%), Gaps = 17/295 (6%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 + + R LG+G FG V + T E VAVK L ++ Sbjct 579 NRRFTYSEVVTMTNNFERVLGKGGFGMVYHGTVNNT-----EQVAVKMLSHSSSQGYKE- 632 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQ 999 +K E+++L ++H++++ G C++ ++L L+ EY+ G LR+++ + Sbjct 633 FKAEVELLLRVHHKNLVGLVGYCDEG--ENLALIYEYMANGDLREHMSGKRGGSILNWET 690 Query 1000 LLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 L + +G+ YLH +HRD+ N+LL+ K+ DFGL+++ P E + Sbjct 691 RLKIVVESAQGLEYLHNGCKPPMVHRDVKTTNILLNEHLHAKLADFGLSRSFPIEGETHV 750 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 +P + PE + SDV+SFG+ L E++T+ K + Sbjct 751 STVVAGTP-GYLDPEYYRTNWLNEKSDVYSFGIVLLEIITNQLVINQSREK-PHIAEWVG 808 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +T + +++ L +C ++ RPT ++ L Sbjct 809 LMLTKGDIQNIMDPKLYGDYDSGSVWRAVELAMSCLNPSSARRPTMSQVVIELNE 863 Score = 218 bits (555), Expect = 3e-57, Method: Composition-based stats. Identities = 71/337 (21%), Positives = 116/337 (34%), Gaps = 61/337 (18%) Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 + S + +R + ++ T N + ++ V LG+G VY G + Sbjct 556 PSSYTQVSEVRTIRSSESAIMTKN-RRFTYSEVVTMTNNFERVLGKGGFGMVYHGTVNNT 614 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 +V +K+L S F L+ +V H +L Sbjct 615 E-------------------------QVAVKMLSHSSSQGYKEFKAEVELLLRVHHKNLV 649 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN-- 727 + G C G ++ EY+ +G L + +RG + W ++ + + A L YL N Sbjct 650 GLVGYCDEGENLALIYEYMANGDLREHMSGKRGGSILNWETRLKIVVESAQGLEYLHNGC 709 Query 728 -KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERV-----ERIPWLA 780 +VH +V NILL KL+D G+ + E V +L Sbjct 710 KPPMVHRDVKTTNILLNE-------HLHAKLADFGLSRSFPIEGETHVSTVVAGTPGYLD 762 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR---SPSEKEHFYQRQHRLPEPS 837 PE N L+ D + FG LLEI + QSR +E + + Sbjct 763 PEYYRT--NWLNEKSDVYSFGIVLLEIITNQLVINQSREKPHIAEWVGLMLTKGDIQNIM 820 Query 838 CPQLA------------TLTSQCLTYEPTQRPSFRTI 862 P+L L CL +RP+ + Sbjct 821 DPKLYGDYDSGSVWRAVELAMSCLNPSSARRPTMSQV 857 >sp|Q13308|PTK7_HUMAN Inactive tyrosine-protein kinase 7 OS=Homo sapiens OX=9606 GN=PTK7 PE=1 SV=2 Length=1070 Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 91/335 (27%), Positives = 145/335 (43%), Gaps = 30/335 (9%) Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 +CL P Q +++ L T S + L+ I LG+ Sbjct 746 MECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATNKRHSTSDKMHFPRSS-LQPITTLGK 804 Query 906 GHFGKVSLYCYDPTNDGTGE-MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKG 964 FG+V L +G E +V VK+L Q + +++E+++ L H ++++ G Sbjct 805 SEFGEVFLAKAQGLEEGVAETLVLVKSL-QSKDEQQQLDFRRELEMFGKLNHANVVRLLG 863 Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYL----------PRHSIGLAQLLLFAQQICEGMAYL 1014 C + +V+EYV LG L+ +L + Q + Q+ GM +L Sbjct 864 LCREAEPH--YMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALCTQVALGMEHL 921 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 ++H+DLAARN L+ R VK+ GL+K V Y+ P+ W +PE + Sbjct 922 SNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHF--RQAWVPLRWMSPEAIL 979 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 E F SDVW+FGV ++E+ TH + GQ L +L RL Sbjct 980 EGDFSTKSDVWAFGVLMWEVFTHGEMPHG-------------GQADDEVLADLQAGKARL 1026 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P+P+ CP ++Y LM+ CW RP+F + L Sbjct 1027 PQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASAL 1061 Score = 220 bits (560), Expect = 2e-57, Method: Composition-based stats. Identities = 77/338 (23%), Positives = 128/338 (38%), Gaps = 47/338 (14%) Query 544 CFSLRRCCLPQPG-ETSNLIIMRGARASPRTLN--LSQLSFHRVDQKEITQLSHLGQGTR 600 C + QP E + + + P N S + + ++ LG+ Sbjct 748 CLNGGPLQNGQPSAEIQEEVALTSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEF 807 Query 601 TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS 660 V+ + + G E V++K L L F Sbjct 808 GEVFLAKAQGLEEGVA-------------------ETLVLVKSLQSKDEQQQLDFRRELE 848 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH------VPMAWKMVV 714 + +++H ++ + G+C + MV EYV+ G L +LR + P++ K V Sbjct 849 MFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKV 908 Query 715 AQ--QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 A Q+A + +L N VH ++ RN L++ +K+S G+ + E Sbjct 909 ALCTQVALGMEHLSNNRFVHKDLAARNCLVS-------AQRQVKVSALGLSKDVYNSEYY 961 Query 773 VER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HF 826 R + W++PE + G ST D W FG + E+ GE P ++ E Sbjct 962 HFRQAWVPLRWMSPEAILEG--DFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADL 1019 Query 827 YQRQHRLPEPS-CP-QLATLTSQCLTYEPTQRPSFRTI 862 + RLP+P CP +L L +C P RPSF I Sbjct 1020 QAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEI 1057 >sp|Q9JI11|STK4_MOUSE Serine/threonine-protein kinase 4 OS=Mus musculus OX=10090 GN=Stk4 PE=1 SV=1 Length=487 Score = 231 bits (589), Expect = 1e-64, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 +K C R T L+ Sbjct 250 WSDNFMDFVKQCLVKSPEQRATATQLLQ 277 Score = 203 bits (516), Expect = 5e-55, Method: Composition-based stats. Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L + S + ++ L LG+G+ +VY+ + G Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K + + S+M Q H+ +G + + +V EY G + Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + Q L YL +H ++ NILL G Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163 Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D GV R + W+APE + + D W G T +E+ +G Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220 Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P P R PE QCL P QR + +L+ Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFMDFVKQCLVKSPEQRATATQLLQHPF 280 >sp|Q9FZB8|Y5181_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g51810 OS=Arabidopsis thaliana OX=3702 GN=At1g51810 PE=1 SV=1 Length=871 Score = 240 bits (612), Expect = 1e-64, Method: Composition-based stats. Identities = 72/335 (21%), Positives = 128/335 (38%), Gaps = 20/335 (6%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 L C+ + L + + T+ + + L Sbjct 527 LMIFCVVRKNNPSNDEAPTSCM---LPADSRSSEPTIVTKNKKFTYAEVLTMTNNFQKIL 583 Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963 G+G FG V + T E VAVK L Q +K E+++L ++H++++ Sbjct 584 GKGGFGIVYYGSVNGT-----EQVAVKMLSH-SSAQGYKQFKAEVELLLRVHHKNLVGLV 637 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQH- 1018 G CE+ + L L+ EY+ G L +++ + L A + +G+ YLH Sbjct 638 GYCEEGDK--LALIYEYMANGDLDEHMSGKRGGSILNWGTRLKIALEAAQGLEYLHNGCK 695 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRD+ N+LL+ K+ DFGL+++ P E + V + + PE + Sbjct 696 PLMVHRDVKTTNILLNEHFDTKLADFGLSRSFPIEGETH-VSTVVAGTIGYLDPEYYRTN 754 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 SDV+SFGV L ++T+ K + G +T + + + Sbjct 755 WLTEKSDVYSFGVVLLVMITNQPVIDQNREK-RHIAEWVGGMLTKGDIKSITDPNLLGDY 813 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + L +C + RPT ++ LK Sbjct 814 NSGSVWKAVELAMSCMNPSSMTRPTMSQVVFELKE 848 Score = 212 bits (540), Expect = 2e-55, Method: Composition-based stats. Identities = 70/352 (20%), Positives = 116/352 (33%), Gaps = 63/352 (18%) Query 540 AGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL---SQLSFHRVDQKEITQLSHLG 596 F + R P E ++ S + + ++ V LG Sbjct 525 VALMIFCVVRKNNPSNDEAPTSCMLPADSRSSEPTIVTKNKKFTYAEVLTMTNNFQKILG 584 Query 597 QGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFY 656 +G VY G + +V +K+L S F Sbjct 585 KGGFGIVYYGSVNGTE-------------------------QVAVKMLSHSSAQGYKQFK 619 Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVV 714 L+ +V H +L + G C G + ++ EY+ +G LD + +RG + W ++ + Sbjct 620 AEVELLLRVHHKNLVGLVGYCEEGDKLALIYEYMANGDLDEHMSGKRGGSILNWGTRLKI 679 Query 715 AQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSRE 770 A + A L YL N +VH +V NILL KL+D G+ + E Sbjct 680 ALEAAQGLEYLHNGCKPLMVHRDVKTTNILLNE-------HFDTKLADFGLSRSFPIEGE 732 Query 771 ERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 V I +L PE N L+ D + FG LL + + Q+R Sbjct 733 THVSTVVAGTIGYLDPEYYRT--NWLTEKSDVYSFGVVLLVMITNQPVIDQNREKRHIAE 790 Query 826 F---YQRQHRLPEPSCPQL------------ATLTSQCLTYEPTQRPSFRTI 862 + + + + P L L C+ RP+ + Sbjct 791 WVGGMLTKGDIKSITDPNLLGDYNSGSVWKAVELAMSCMNPSSMTRPTMSQV 842 >sp|P04412|EGFR_DROME Epidermal growth factor receptor OS=Drosophila melanogaster OX=7227 GN=Egfr PE=1 SV=3 Length=1426 Score = 244 bits (623), Expect = 1e-64, Method: Composition-based stats. Identities = 90/269 (33%), Positives = 137/269 (51%), Gaps = 20/269 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG+V + P + VA+K L G + + +E I+ + H +++K Sbjct 944 LGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKL 1003 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 C + L+ + +PLG L DY+ R IG LL ++ QI +GM+YL + + Sbjct 1004 LAVCMSS---QMMLITQLMPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLV 1060 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLAARNVL+ LVKI DFGLAK + Y+ G P+ W A EC++ F Sbjct 1061 HRDLAARNVLVQTPSLVKITDFGLAKLLSSDSNEYKA-AGGKMPIKWLALECIRNRVFTS 1119 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVW+FGVT++ELLT + + +L+E G +L +P+ C Sbjct 1120 KSDVWAFGVTIWELLTFGQR--------------PHENIPAKDIPDLIEVGLKLEQPEIC 1165 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPIL 1169 ++Y + +CW +A+ RPTF+ L + Sbjct 1166 SLDIYCTLLSCWHLDAAMRPTFKQLTTVF 1194 Score = 223 bits (567), Expect = 9e-58, Method: Composition-based stats. Identities = 65/301 (22%), Positives = 120/301 (40%), Gaps = 39/301 (13%) Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 P + + V E+ + LG G VY+G EG Sbjct 920 PSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPEGENV--------------- 964 Query 631 RDRGQELRVVLK-VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 ++ V +K +L + + + F A +M+ H +L + VC+ + +++T+ Sbjct 965 -----KIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKLLAVCM-SSQMMLITQL 1018 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 + G L ++R R + + + Q+A +SYLE K LVH ++ RN+L+ Sbjct 1019 MPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLV------- 1071 Query 750 GTSPFIKLSDPGVGLGALSREERVE------RIPWLAPECLPGGANSLSTAMDKWGFGAT 803 T +K++D G+ S + I WLA EC+ ++ D W FG T Sbjct 1072 QTPSLVKITDFGLAKLLSSDSNEYKAAGGKMPIKWLALECIRNRV--FTSKSDVWAFGVT 1129 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRT 861 + E+ G+ P ++ + + +L PE + C + RP+F+ Sbjct 1130 IWELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLSCWHLDAAMRPTFKQ 1189 Query 862 I 862 + Sbjct 1190 L 1190 >sp|Q13043|STK4_HUMAN Serine/threonine-protein kinase 4 OS=Homo sapiens OX=9606 GN=STK4 PE=1 SV=2 Length=487 Score = 231 bits (589), Expect = 1e-64, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 +K C R T L+ Sbjct 250 WSDNFTDFVKQCLVKSPEQRATATQLLQ 277 Score = 203 bits (516), Expect = 6e-55, Method: Composition-based stats. Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L + S + ++ L LG+G+ +VY+ + G Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K + + S+M Q H+ +G + + +V EY G + Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + Q L YL +H ++ NILL G Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163 Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D GV R + W+APE + + D W G T +E+ +G Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220 Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P P R PE QCL P QR + +L+ Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPF 280 >sp|Q9LV48|PERK1_ARATH Proline-rich receptor-like protein kinase PERK1 OS=Arabidopsis thaliana OX=3702 GN=PERK1 PE=1 SV=1 Length=652 Score = 235 bits (600), Expect = 1e-64, Method: Composition-based stats. Identities = 78/298 (26%), Positives = 126/298 (42%), Gaps = 24/298 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V +G+ VAVK LKA G R ++ E++I+ ++H H++ Sbjct 286 LGQGGFGYVHKGIL-----PSGKEVAVKQLKAGSGQGERE-FQAEVEIISRVHHRHLVSL 339 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH---A 1016 G C ++ LV E+VP +L +L R ++ + L A +G++YLH Sbjct 340 IGYCMAGVQR--LLVYEFVPNNNLEFHLHGKGRPTMEWSTRLKIALGSAKGLSYLHEDCN 397 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ A N+L+D K+ DFGLAK + + + R + APE Sbjct 398 PKIIHRDIKASNILIDFKFEAKVADFGLAKIASDTNTHVSTR--VMGTFGYLAPEYAASG 455 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVL----RLTELLERG 1131 K SDV+SFGV L EL+T + L+ A+ + L + Sbjct 456 KLTEKSDVFSFGVVLLELITGRRPVDANNVYVDDSLVDWARPLLNRASEEGDFEGLADSK 515 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK---TVHEKYQGQAPSVFSV 1186 + + C A RP ++ L+ ++ + +G P +V Sbjct 516 MGNEYDREEMARMVACAAACVRHSARRRPRMSQIVRALEGNVSLSDLNEGMRPGHSNV 573 Score = 221 bits (564), Expect = 7e-60, Method: Composition-based stats. Identities = 59/259 (23%), Positives = 98/259 (38%), Gaps = 47/259 (18%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 S T +LS ++ + LGQG V++G L Sbjct 264 SKSTFTYEELS---RATNGFSEANLLGQGGFGYVHKGILPSGK----------------- 303 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 V +K L F ++S+V H HL + G C+ G + ++V E+ Sbjct 304 --------EVAVKQLKAGSGQGEREFQAEVEIISRVHHRHLVSLIGYCMAGVQRLLVYEF 355 Query 690 VEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745 V + L+ L + R + + ++ +A A LSYL ++H ++ NIL+ Sbjct 356 VPNNNLEFHLHGKGRPTMEWSTRLKIALGSAKGLSYLHEDCNPKIIHRDIKASNILIDFK 415 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800 A K++D G+ A V +LAPE G L+ D + F Sbjct 416 FEA-------KVADFGLAKIASDTNTHVSTRVMGTFGYLAPEYAASG--KLTEKSDVFSF 466 Query 801 GATLLEICFDGEAPLQSRS 819 G LLE+ G P+ + + Sbjct 467 GVVLLELI-TGRRPVDANN 484 >sp|A4K2Y1|STK4_CHLAE Serine/threonine-protein kinase 4 OS=Chlorocebus aethiops OX=9534 GN=STK4 PE=3 SV=1 Length=487 Score = 231 bits (588), Expect = 1e-64, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 +K C R T L+ Sbjct 250 WSDNFTDFVKQCLVKSPEQRATATQLLQ 277 Score = 202 bits (515), Expect = 6e-55, Method: Composition-based stats. Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L + S + ++ L LG+G+ +VY+ + G Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K + + S+M Q H+ +G + + +V EY G + Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + Q L YL +H ++ NILL G Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163 Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D GV R + W+APE + + D W G T +E+ +G Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220 Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P P R PE QCL P QR + +L+ Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPF 280 >sp|A4K2T0|STK4_MACMU Serine/threonine-protein kinase 4 OS=Macaca mulatta OX=9544 GN=STK4 PE=3 SV=1 Length=487 Score = 231 bits (588), Expect = 1e-64, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 +K C R T L+ Sbjct 250 WSDNFTDFVKQCLVKSPEQRATATQLLQ 277 Score = 202 bits (515), Expect = 6e-55, Method: Composition-based stats. Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L + S + ++ L LG+G+ +VY+ + G Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K + + S+M Q H+ +G + + +V EY G + Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + Q L YL +H ++ NILL G Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163 Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D GV R + W+APE + + D W G T +E+ +G Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220 Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P P R PE QCL P QR + +L+ Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPF 280 >sp|Q8VYT3|Y4052_ARATH Probable LRR receptor-like serine/threonine-protein kinase At4g30520 OS=Arabidopsis thaliana OX=3702 GN=At4g30520 PE=1 SV=1 Length=648 Score = 235 bits (600), Expect = 1e-64, Method: Composition-based stats. Identities = 75/274 (27%), Positives = 121/274 (44%), Gaps = 15/274 (5%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V G G MVAVK LK G S ++ E++++ H+++++ Sbjct 309 LGAGGFGNVYRG-----KLGDGTMVAVKRLKDINGTSGDSQFRMELEMISLAVHKNLLRL 363 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ---H 1018 G C GE+ LV Y+P GS+ L + ++ A G+ YLH Q Sbjct 364 IGYCATSGER--LLVYPYMPNGSVASKLKSKPALDWNMRKRIAIGAARGLLYLHEQCDPK 421 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ A N+LLD +GDFGLAK + + V V APE L + Sbjct 422 IIHRDVKAANILLDECFEAVVGDFGLAKLLNHADSH--VTTAVRGTVGHIAPEYLSTGQS 479 Query 1079 YYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 +DV+ FG+ L EL+T + ++ ++ + +++ ELL+R Sbjct 480 SEKTDVFGFGILLLELITGLRALEFGKTVSQKGAMLEWVRKLHEEMKVEELLDRELGTNY 539 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 E+ + C + + RP ++ +L+ Sbjct 540 DKIEVGEMLQVALLCTQYLPAHRPKMSEVVLMLE 573 Score = 190 bits (482), Expect = 2e-49, Method: Composition-based stats. Identities = 65/320 (20%), Positives = 107/320 (33%), Gaps = 64/320 (20%) Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 NL +F V + + LG G NVY G+L Sbjct 287 NLRSFTFRELHVYTDGFSSKNILGAGGFGNVYRGKL------------------------ 322 Query 633 RGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 G V +K L + F ++S H +L + G C E ++V Y+ Sbjct 323 -GDGTMVAVKRLKDINGTSGDSQFRMELEMISLAVHKNLLRLIGYCATSGERLLVYPYMP 381 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748 +G + L + + + + +A A L YL + ++H +V NILL A Sbjct 382 NGSVASKL-KSKPALDWNMRKRIAIGAARGLLYLHEQCDPKIIHRDVKAANILLDECFEA 440 Query 749 EGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 + D G+ + V + +APE L G + S D +GFG Sbjct 441 V-------VGDFGLAKLLNHADSHVTTAVRGTVGHIAPEYLSTGQS--SEKTDVFGFGIL 491 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS------------------CPQLATLT 845 LLE+ A ++ S+K + +L E ++ + Sbjct 492 LLELITGLRALEFGKTVSQKGAMLEWVRKLHEEMKVEELLDRELGTNYDKIEVGEMLQVA 551 Query 846 SQCLTYEPTQRPSFRTILRD 865 C Y P RP ++ Sbjct 552 LLCTQYLPAHRPKMSEVVLM 571 >sp|A4K2M3|STK4_PAPAN Serine/threonine-protein kinase 4 OS=Papio anubis OX=9555 GN=STK4 PE=3 SV=1 Length=487 Score = 231 bits (588), Expect = 1e-64, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 146 IHRDIKAGNILLNTEGQAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 +K C R T L+ Sbjct 250 WSDNFTDFVKQCLVKSPEQRATATQLLQ 277 Score = 203 bits (516), Expect = 5e-55, Method: Composition-based stats. Identities = 60/300 (20%), Positives = 97/300 (32%), Gaps = 44/300 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L + S + ++ L LG+G+ +VY+ + G Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K + + S+M Q H+ +G + + +V EY G + Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + Q L YL +H ++ NILL G A Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGQA------- 163 Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D GV R + W+APE + + D W G T +E+ +G Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220 Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P P R PE QCL P QR + +L+ Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPF 280 >sp|Q9SX31|PERK9_ARATH Proline-rich receptor-like protein kinase PERK9 OS=Arabidopsis thaliana OX=3702 GN=PERK9 PE=1 SV=1 Length=708 Score = 236 bits (603), Expect = 1e-64, Method: Composition-based stats. Identities = 72/283 (25%), Positives = 116/283 (41%), Gaps = 20/283 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG V G +VAVK LK G R +K E++ L ++H H++ Sbjct 383 LGEGGFGCVYKGIL-----PDGRVVAVKQLKIGGGQGDRE-FKAEVETLSRIHHRHLVSI 436 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLH---AQ 1017 G C + L+ +YV L +L + + A + A G+AYLH Sbjct 437 VGHCISGDRR--LLIYDYVSNNDLYFHLHGEKSVLDWATRVKIAAGAARGLAYLHEDCHP 494 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 IHRD+ + N+LL+++ ++ DFGLA+ + + + R + APE K Sbjct 495 RIIHRDIKSSNILLEDNFDARVSDFGLARLALDCNTHITTR--VIGTFGYMAPEYASSGK 552 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQG----QMTVLRLTELLERGE 1132 SDV+SFGV L EL+T S P L+ A+ + L + Sbjct 553 LTEKSDVFSFGVVLLELITGRKPVDTSQPLGDESLVEWARPLISHAIETEEFDSLADPKL 612 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 + + C A+ RP ++ +++ + Sbjct 613 GGNYVESEMFRMIEAAGACVRHLATKRPRMGQIVRAFESLAAE 655 Score = 225 bits (573), Expect = 1e-60, Method: Composition-based stats. Identities = 60/315 (19%), Positives = 107/315 (34%), Gaps = 44/315 (14%) Query 527 RELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ 586 ++ + R+ F ++ + S + S + Sbjct 316 GDVTPSPMSSTARSDSAFFRMQSSAPVGASKRSGSYQSQSGGLGNSKALFSYEELVK-AT 374 Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 +Q + LG+G VY+G L V +K L Sbjct 375 NGFSQENLLGEGGFGCVYKGILPDGR-------------------------VVAVKQLKI 409 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 F +S++ H HL + G C+ G +++ +YV + L L E+ + Sbjct 410 GGGQGDREFKAEVETLSRIHHRHLVSIVGHCISGDRRLLIYDYVSNNDLYFHLHGEKSVL 469 Query 707 PMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 A ++ +A A L+YL ++H ++ NILL + ++SD G+ Sbjct 470 DWATRVKIAAGAARGLAYLHEDCHPRIIHRDIKSSNILL-------EDNFDARVSDFGLA 522 Query 764 LGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 AL + ++APE G L+ D + FG LLE+ G P+ + Sbjct 523 RLALDCNTHITTRVIGTFGYMAPEYASSG--KLTEKSDVFSFGVVLLELI-TGRKPVDTS 579 Query 819 SPSEKEHFYQRQHRL 833 P E + L Sbjct 580 QPLGDESLVEWARPL 594 >sp|O23081|CRK41_ARATH Cysteine-rich receptor-like protein kinase 41 OS=Arabidopsis thaliana OX=3702 GN=CRK41 PE=3 SV=2 Length=665 Score = 236 bits (601), Expect = 1e-64, Method: Composition-based stats. Identities = 73/282 (26%), Positives = 117/282 (41%), Gaps = 18/282 (6%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 + LGEG FG V D GE +AVK L G Q + + E+ ++ L H + Sbjct 346 RDNQLGEGGFGAVYKGVLD-----YGEEIAVKRLSMKSG-QGDNEFINEVSLVAKLQHRN 399 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYL 1014 +++ G C QGE+ + L+ E+ SL Y+ R + + G+ YL Sbjct 400 LVRLLGFCL-QGEERI-LIYEFFKNTSLDHYIFDSNRRMILDWETRYRIISGVARGLLYL 457 Query 1015 HAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY-RVREDGDSPVFWYAP 1070 H +HRD+ A NVLLD+ KI DFG+AK R + AP Sbjct 458 HEDSRFKIVHRDMKASNVLLDDAMNPKIADFGMAKLFDTDQTSQTRFTSKVAGTYGYMAP 517 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQMTVLRLTELLE 1129 E +F +DV+SFGV + E++ ++ SP L L+ + +++ Sbjct 518 EYAMSGEFSVKTDVFSFGVLVLEIIKGKKNNWSPEEDSSLFLLSYVWKSWREGEVLNIVD 577 Query 1130 RGERLPRP-DKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + H+ C + A RPT +++ +L Sbjct 578 PSLVETIGVSDEIMKCIHIGLLCVQENAESRPTMASVVVMLN 619 Score = 219 bits (558), Expect = 6e-59, Method: Composition-based stats. Identities = 56/266 (21%), Positives = 103/266 (39%), Gaps = 52/266 (20%) Query 572 RTLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 + L QL F + + ++ + LG+G VY+G L Sbjct 325 KDAQLLQLDFDTIRLATNDFSRDNQLGEGGFGAVYKGVL--------------------- 363 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 D G+E + +K L F SL++++ H +L + G C++G E I++ E+ Sbjct 364 --DYGEE--IAVKRLSMKSGQGDNEFINEVSLVAKLQHRNLVRLLGFCLQGEERILIYEF 419 Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744 ++ LD ++ + + W + + +A L YL +VH ++ N+LL Sbjct 420 FKNTSLDHYIFDSNRRMILDWETRYRIISGVARGLLYLHEDSRFKIVHRDMKASNVLLD- 478 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER--------VERIPWLAPECLPGGANSLSTAMD 796 + K++D G+ + + ++APE G S D Sbjct 479 ------DAMNPKIADFGMAKLFDTDQTSQTRFTSKVAGTYGYMAPEYAMSG--EFSVKTD 530 Query 797 KWGFGATLLEICFDGEAPLQSRSPSE 822 + FG +LEI + + SP E Sbjct 531 VFSFGVLVLEIIKGKK---NNWSPEE 553 >sp|Q9ZUE0|PEK12_ARATH Proline-rich receptor-like protein kinase PERK12 OS=Arabidopsis thaliana OX=3702 GN=PERK12 PE=2 SV=2 Length=720 Score = 237 bits (604), Expect = 1e-64, Method: Composition-based stats. Identities = 76/279 (27%), Positives = 119/279 (43%), Gaps = 21/279 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LGEG FG V G++VAVK LKA G R +K E++I+ ++H H++ Sbjct 377 LGEGGFGCVYKGTLQ-----DGKVVAVKQLKAGSGQGDRE-FKAEVEIISRVHHRHLVSL 430 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAYLH---A 1016 G C + L+ EYV +L +L + ++ + A +G+AYLH Sbjct 431 VGYCISDQHR--LLIYEYVSNQTLEHHLHGKGLPVLEWSKRVRIAIGSAKGLAYLHEDCH 488 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ + N+LLD++ ++ DFGLA+ + R + APE Sbjct 489 PKIIHRDIKSANILLDDEYEAQVADFGLARLNDTTQTHVSTR--VMGTFGYLAPEYASSG 546 Query 1077 KFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQG----QMTVLRLTELLERG 1131 K SDV+SFGV L EL+T Q+ P L+ A+ + L+EL++ Sbjct 547 KLTDRSDVFSFGVVLLELVTGRKPVDQTQPLGEESLVEWARPLLLKAIETGDLSELIDTR 606 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + + C RP ++ L Sbjct 607 LEKRYVEHEVFRMIETAAACVRHSGPKRPRMVQVVRALD 645 Score = 217 bits (553), Expect = 5e-58, Method: Composition-based stats. Identities = 66/365 (18%), Positives = 122/365 (33%), Gaps = 49/365 (13%) Query 481 YRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGW--GRSFPSVRELGAALQGCLL 538 + L ++ + D + P L G G+ + S Sbjct 262 GVVFLVRRKKKRNIDSYNHSQYLPHPNFSVKSDGFLYGQDPGKGYSSGPNGSMYNNSQQQ 321 Query 539 RAG-DDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQ 597 ++ + + P S+ S +T + S + + + + LG+ Sbjct 322 QSSMGNSYGTAGGGYPHHQMQSSGTPDSAILGSGQT-HFSYEELAEI-TQGFARKNILGE 379 Query 598 GTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE 657 G VY+G L+ V +K L F Sbjct 380 GGFGCVYKGTLQDGK-------------------------VVAVKQLKAGSGQGDREFKA 414 Query 658 TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQ 716 ++S+V H HL + G C+ +++ EYV + L+ L + + + ++ +A Sbjct 415 EVEIISRVHHRHLVSLVGYCISDQHRLLIYEYVSNQTLEHHLHGKGLPVLEWSKRVRIAI 474 Query 717 QLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 A L+YL ++H ++ NILL A+ ++D G+ + + V Sbjct 475 GSAKGLAYLHEDCHPKIIHRDIKSANILLDDEYEAQ-------VADFGLARLNDTTQTHV 527 Query 774 -----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 +LAPE G L+ D + FG LLE+ G P+ P +E + Sbjct 528 STRVMGTFGYLAPEYASSG--KLTDRSDVFSFGVVLLELV-TGRKPVDQTQPLGEESLVE 584 Query 829 RQHRL 833 L Sbjct 585 WARPL 589 >sp|Q8RY17|WAKLI_ARATH Wall-associated receptor kinase-like 22 OS=Arabidopsis thaliana OX=3702 GN=WAKL22 PE=2 SV=1 Length=751 Score = 237 bits (605), Expect = 1e-64, Method: Composition-based stats. Identities = 71/291 (24%), Positives = 118/291 (41%), Gaps = 26/291 (9%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R LG+G G V G +VAVK K + E+ +L + Sbjct 419 DNFNMNRVLGQGGQGTVYKGML-----VDGRIVAVKRSKV-LDEDKVEEFINEVGVLSQI 472 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEG 1010 H +I+K GCC + E + LV E++P G L L +++ L + +I Sbjct 473 NHRNIVKLMGCCLE-TEVPI-LVYEHIPNGDLFKRLHHDSDDYTMTWDVRLRISVEIAGA 530 Query 1011 MAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 +AYLH+ HRD+ N+LLD K+ DFG ++++ + + + Sbjct 531 LAYLHSAASTPVYHRDVKTTNILLDEKYRAKVSDFGTSRSINVDQTH--LTTLVAGTFGY 588 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTE 1126 PE + +F SDV+SFGV L EL+T P + L+ M R+ + Sbjct 589 LDPEYFQTSQFTDKSDVYSFGVVLVELITGEKPFSVMRPEENRGLVSHFNEAMKQNRVLD 648 Query 1127 LLERGERLPRPDKCPCE----VYHLMKNCWETEASFRPTFENLIPILKTVH 1173 +++ + + C E V L + C + RP + L+ + Sbjct 649 IVDSRIK----EGCTLEQVLAVAKLARRCLSLKGKKRPNMREVSVELERIR 695 Score = 221 bits (563), Expect = 4e-59, Method: Composition-based stats. Identities = 72/369 (20%), Positives = 127/369 (34%), Gaps = 66/369 (18%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 L G S + + +L LGQG + VY+G L Sbjct 393 KQQLTTRGGNVQSSKIFSSKELEK---ATDNFNMNRVLGQGGQGTVYKGMLVDGRI---- 445 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 V +K D F ++SQ++H ++ + G C Sbjct 446 ---------------------VAVKRSKVLDEDKVEEFINEVGVLSQINHRNIVKLMGCC 484 Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVH 732 + I+V E++ +G L L + M W ++ ++ ++A AL+YL + + H Sbjct 485 LETEVPILVYEHIPNGDLFKRLHHDSDDYTMTWDVRLRISVEIAGALAYLHSAASTPVYH 544 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGG 787 +V NILL A K+SD G + +L PE Sbjct 545 RDVKTTNILLDEKYRA-------KVSDFGTSRSINVDQTHLTTLVAGTFGYLDPEYFQT- 596 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE----KEHFY--QRQHRLPEPSCPQL 841 + + D + FG L+E+ GE P P E HF +Q+R+ + ++ Sbjct 597 -SQFTDKSDVYSFGVVLVELI-TGEKPFSVMRPEENRGLVSHFNEAMKQNRVLDIVDSRI 654 Query 842 ------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 A L +CL+ + +RP+ R + +L R++ L + + Sbjct 655 KEGCTLEQVLAVAKLARRCLSLKGKKRPNMREVSVELERIRSSPEDLELHIEEEDEEECA 714 Query 890 TVFHKRYLK 898 + Sbjct 715 MEINMDDSW 723 >sp|Q9FNE1|CRK42_ARATH Cysteine-rich receptor-like protein kinase 42 OS=Arabidopsis thaliana OX=3702 GN=CRK42 PE=2 SV=1 Length=651 Score = 235 bits (599), Expect = 1e-64, Method: Composition-based stats. Identities = 80/308 (26%), Positives = 126/308 (41%), Gaps = 23/308 (7%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935 + + Y + LG+G G V L G+ VAVK L Sbjct 294 RKFNNSKTKFKYETLEKATDYFSHKKMLGQGGNGTVFLGIL-----PNGKNVAVKRL-VF 347 Query 936 CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS- 994 + E++++ + H++++K GC + E LV EYVP SL +L S Sbjct 348 NTRDWVEEFFNEVNLISGIQHKNLVKLLGCSIEGPES--LLVYEYVPNKSLDQFLFDESQ 405 Query 995 ---IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + +Q L EG+AYLH IHRD+ NVLLD+ KI DFGLA+ Sbjct 406 SKVLNWSQRLNIILGTAEGLAYLHGGSPVRIIHRDIKTSNVLLDDQLNPKIADFGLARCF 465 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 G + + + + APE + + +DV+SFGV + E+ + P + Sbjct 466 --GLDKTHLSTGIAGTLGYMAPEYVVRGQLTEKADVYSFGVLVLEIACGTRINAFVP-ET 522 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPR-----PDKCPCEVYHLMKNCWETEASFRPTFE 1163 L+ T+ RL E L+ + + C+V + C + S RP+ E Sbjct 523 GHLLQRVWNLYTLNRLVEALDPCLKDEFLQVQGSEAEACKVLRVGLLCTQASPSLRPSME 582 Query 1164 NLIPILKT 1171 +I +L Sbjct 583 EVIRMLTE 590 Score = 215 bits (547), Expect = 1e-57, Method: Composition-based stats. Identities = 70/357 (20%), Positives = 120/357 (34%), Gaps = 68/357 (19%) Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615 E NL ++ + +T + + LGQG V+ G L + Sbjct 284 QEKRNLGLVSRKFNNSKTK--FKYETLEKATDYFSHKKMLGQGGNGTVFLGILPNGKN-- 339 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675 V +K L + D F+ +L+S + H +L + G Sbjct 340 -----------------------VAVKRLVFNTRDWVEEFFNEVNLISGIQHKNLVKLLG 376 Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRE--RGHVPMAWKMVVAQQLASALSYLENK---NL 730 + GPE+++V EYV + LD +L E + + ++ + A L+YL + Sbjct 377 CSIEGPESLLVYEYVPNKSLDQFLFDESQSKVLNWSQRLNIILGTAEGLAYLHGGSPVRI 436 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLP 785 +H ++ N+LL K++D G+ + + ++APE + Sbjct 437 IHRDIKTSNVLLDDQLNP-------KIADFGLARCFGLDKTHLSTGIAGTLGYMAPEYVV 489 Query 786 GGANSLSTAMDKWGFGATLLEICFDGE----APLQSRSPSEKEHFYQRQHRLPEPSCPQL 841 G L+ D + FG +LEI P + Y +RL E P L Sbjct 490 RG--QLTEKADVYSFGVLVLEIACGTRINAFVPETGHLLQRVWNLYT-LNRLVEALDPCL 546 Query 842 ATLTSQ-----------------CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 Q C P+ RPS ++R LT + Sbjct 547 KDEFLQVQGSEAEACKVLRVGLLCTQASPSLRPSMEEVIRMLTERDYPIPSPTSPPF 603 >sp|Q8RY67|WAKLO_ARATH Wall-associated receptor kinase-like 14 OS=Arabidopsis thaliana OX=3702 GN=WAKL14 PE=2 SV=2 Length=708 Score = 236 bits (603), Expect = 2e-64, Method: Composition-based stats. Identities = 71/283 (25%), Positives = 122/283 (43%), Gaps = 20/283 (7%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 + LG G +G V E VA+K L+ + EI +L ++ H +++ Sbjct 352 QKLGIGAYGTVYRGKLQ-----NDEWVAIKRLRHRDS-ESLDQVMNEIKLLSSVSHPNLV 405 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHAQ 1017 + GCC +QG+ LV EY+P G+L ++L R + L A Q + +AYLH+ Sbjct 406 RLLGCCIEQGDP--VLVYEYMPNGTLSEHLQRDRGSGLPWTLRLTVATQTAKAIAYLHSS 463 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 HRD+ + N+LLD D K+ DFGL++ + G + P+ + Sbjct 464 MNPPIYHRDIKSTNILLDYDFNSKVADFGLSRLGMTESSHISTAPQG--TPGYLDPQYHQ 521 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + SDV+SFGV L E++T + P + L +A ++ + E+++ Sbjct 522 CFHLSDKSDVYSFGVVLAEIITGLKVVDFTRPHTEINLAALAVDKIGSGCIDEIIDPILD 581 Query 1134 LPRPDKCPCEVY---HLMKNCWETEASFRPTFENLIPILKTVH 1173 L ++ L C + RPT + L+ + Sbjct 582 LDLDAWTLSSIHTVAELAFRCLAFHSDMRPTMTEVADELEQIR 624 Score = 209 bits (532), Expect = 2e-55, Method: Composition-based stats. Identities = 67/360 (19%), Positives = 123/360 (34%), Gaps = 64/360 (18%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 RR P S ++ A + + ++ LG G VY G+ Sbjct 308 RRRSTPLRSHLSAKRLLSEAAGNSSVAFFPYKEIEK-ATDGFSEKQKLGIGAYGTVYRGK 366 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667 L+ + V +K L + L+S VSH Sbjct 367 LQNDEW-------------------------VAIKRLRHRDSESLDQVMNEIKLLSSVSH 401 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLE 726 +L + G C+ + ++V EY+ +G L L+R+RG +P ++ VA Q A A++YL Sbjct 402 PNLVRLLGCCIEQGDPVLVYEYMPNGTLSEHLQRDRGSGLPWTLRLTVATQTAKAIAYLH 461 Query 727 NK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPW 778 + + H ++ NILL K++D G+ ++ + + Sbjct 462 SSMNPPIYHRDIKSTNILLD-------YDFNSKVADFGLSRLGMTESSHISTAPQGTPGY 514 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838 L P+ LS D + FG L EI + +R +E ++ Sbjct 515 LDPQY--HQCFHLSDKSDVYSFGVVLAEIITGLKVVDFTRPHTEINLAALAVDKIGSGCI 572 Query 839 PQL--------------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 ++ A L +CL + RP+ + +L +++ + Sbjct 573 DEIIDPILDLDLDAWTLSSIHTVAELAFRCLAFHSDMRPTMTEVADELEQIRLSGWIPSM 632 >sp|P83104|M3K7L_DROME Putative mitogen-activated protein kinase kinase kinase 7-like OS=Drosophila melanogaster OX=7227 GN=Takl1 PE=2 SV=1 Length=393 Score = 227 bits (579), Expect = 2e-64, Method: Composition-based stats. Identities = 75/292 (26%), Positives = 125/292 (43%), Gaps = 38/292 (13%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG G G V + + +AVK + ++EI L + HE++I+ Sbjct 16 FLGAGSGGAVRKATFQ------NQEIAVKIFD-FLEETIKKNAEREITHLSEIDHENVIR 68 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA-- 1016 G K L+MEY+ GSL +YL + + Q + +A Q + +AYLH+ Sbjct 69 VIG--RASNGKKDYLLMEYLEEGSLHNYLYGDDKWEYTVEQAVRWALQCAKALAYLHSLD 126 Query 1017 QHYIHRDLAARNVLL-DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + +HRD+ +N+LL + +KI DFGLA + + D + + APE +K Sbjct 127 RPIVHRDIKPQNMLLYNQHEDLKICDFGLATDMSNN------KTDMQGTLRYMAPEAIKH 180 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 K+ DV+SFG+ L+EL+T + + + + GE+LP Sbjct 181 LKYTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQYA-----------IMKAISSGEKLP 229 Query 1136 RP---DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 CP + LM+ C + RP+ + + L E+Y+ F Sbjct 230 MEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIEKFL---GEQYESGTDEDF 278 Score = 180 bits (457), Expect = 3e-48, Method: Composition-based stats. Identities = 58/302 (19%), Positives = 113/302 (37%), Gaps = 50/302 (17%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 + Q+ F V E LG G+ V + Q Sbjct 2 VKQVDFAEVKLSE----KFLGAGSGGAVRKATF--------------------------Q 31 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 + +K+ D I + +S++ H ++ V G G ++ ++ EY+E G L Sbjct 32 NQEIAVKIFDFLEETIKKNAEREITHLSEIDHENVIRVIGRASNGKKDYLLMEYLEEGSL 91 Query 696 DVWLR-RERGHVPMAWKMVVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGLAEGTS 752 +L ++ + + A Q A AL+YL + + +VH ++ +N+LL Sbjct 92 HNYLYGDDKWEYTVEQAVRWALQCAKALAYLHSLDRPIVHRDIKPQNMLLYNQHED---- 147 Query 753 PFIKLSDPGVGLGALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 +K+ D G+ + + + + ++APE + + D + FG L E+ Sbjct 148 --LKICDFGLATDMSNNKTDMQGTLRYMAPEAIKH--LKYTAKCDVYSFGIMLWELMTRQ 203 Query 812 EAPLQSRSPSEKEHFYQR---QHRLP----EPSCPQ-LATLTSQCLTYEPTQRPSFRTIL 863 +P+ + + +LP CP+ + L C+ P +RPS + I Sbjct 204 LPYSHLENPNSQYAIMKAISSGEKLPMEAVRSDCPEGIKQLMECCMDINPEKRPSMKEIE 263 Query 864 RD 865 + Sbjct 264 KF 265 >sp|Q00526|CDK3_HUMAN Cyclin-dependent kinase 3 OS=Homo sapiens OX=9606 GN=CDK3 PE=1 SV=1 Length=305 Score = 224 bits (571), Expect = 2e-64, Method: Composition-based stats. Identities = 72/292 (25%), Positives = 127/292 (43%), Gaps = 30/292 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y N TG++VA+K ++ D + S +EI +L+ Sbjct 1 MDMFQKVEKIGEGTYGVV----YKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009 L H +I++ E+ L LV E++ L+ Y+ P + L + + Q+ + Sbjct 57 ELKHPNIVRLLDVV--HNERKLYLVFEFLSQ-DLKKYMDSTPGSELPLHLIKSYLFQLLQ 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 G+++ H+ IHRDL +N+L++ +K+ DFGLA+A Y +++ A Sbjct 114 GVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTY---THEVVTLWYRA 170 Query 1070 PECLKEYK-FYYASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIGIAQGQMTVLR 1123 PE L K + A D+WS G E++T DS + ++G T Sbjct 171 PEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSED-TWPG 229 Query 1124 LTELLERGERLP---------RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 +T+L + P E L+ + + S R T + + Sbjct 230 VTQLPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTAL 281 Score = 169 bits (429), Expect = 2e-45, Method: Composition-based stats. Identities = 49/263 (19%), Positives = 93/263 (35%), Gaps = 40/263 (15%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--VLDP 646 ++ +G+GT VY+ + R G V LK LD Sbjct 4 FQKVEKIGEGTYGVVYKAKNRETGQ------------------------LVALKKIRLDL 39 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH- 705 + SL+ ++ H ++ + V + +V E++ L ++ G Sbjct 40 EMEGVPSTAIREISLLKELKHPNIVRLLDVVHNERKLYLVFEFLSQ-DLKKYMDSTPGSE 98 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 +P+ QL +S+ + ++H ++ +N+L+ LG IKL+D G+ Sbjct 99 LPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGA-------IKLADFGLARA 151 Query 766 ----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + V + + APE L G +TA+D W G E+ Sbjct 152 FGVPLRTYTHEVVTLWYRAPEILLGSKF-YTTAVDIWSIGCIFAEMVTRKALFPGDSEID 210 Query 822 EKEHFYQRQHRLPEPSCPQLATL 844 + ++ E + P + L Sbjct 211 QLFRIFRMLGTPSEDTWPGVTQL 233 >sp|Q852Q0|OSK3_ORYSJ Serine/threonine protein kinase OSK3 OS=Oryza sativa subsp. japonica OX=39947 GN=OSK3 PE=1 SV=1 Length=508 Score = 231 bits (589), Expect = 2e-64, Method: Composition-based stats. Identities = 74/280 (26%), Positives = 109/280 (39%), Gaps = 30/280 (11%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQE 947 + R LG G FGKV + + TG VA+K L + K+E Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKRE 65 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006 I ILR H HII+ + + +VMEY G L DY+ + + + QQ Sbjct 66 IKILRLFIHPHIIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQ 123 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I G+ Y H +HRDL N+LLD+ VK+ DFGL+ + +G + ++ SP Sbjct 124 IISGVEYCHRNMVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDG---HFLKTSCGSPN- 179 Query 1067 WYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 + APE + + DVWS GV LY LL + L Sbjct 180 YAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE---------------NIPNLF 224 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + ++ G P L+ + R T + Sbjct 225 KKIKGGI-YTLPSHLSALARDLIPRMLVVDPMKRITIREI 263 Score = 182 bits (463), Expect = 8e-48, Method: Composition-based stats. Identities = 53/332 (16%), Positives = 101/332 (30%), Gaps = 39/332 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 H K LG G+ V ++ G RV + Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKIAEHKLTGH------------------------RVAI 45 Query 642 KVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 K+L+ + ++ ++ H H+ ++ V + +V EY + G L + Sbjct 46 KILNRRQMRNMEMEEKAKREIKILRLFIHPHIIRLYEVIYTPTDIYVVMEYCKFGELFDY 105 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + E+G + + QQ+ S + Y +VH ++ N+LL +KL+ Sbjct 106 I-VEKGRLQEDEARRIFQQIISGVEYCHRNMVVHRDLKPENLLLDSK-------YNVKLA 157 Query 759 DPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 D G+ + + APE + G + +D W G L + Sbjct 158 DFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYALLCGTLPFD 216 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 P+ + + LP L + L +P +R + R I Sbjct 217 DENIPNLFKKIKGGIYTLPSHLSALARDLIPRMLVVDPMKRITIREIREHQWFQIRLPRY 276 Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 + + + G+ H Sbjct 277 LAVPPPDTAQQAKMIDEDTLQDVVNLGYGKDH 308 >sp|A2XFF4|OSK3_ORYSI Serine/threonine protein kinase OSK3 OS=Oryza sativa subsp. indica OX=39946 GN=OSK3 PE=3 SV=1 Length=508 Score = 231 bits (589), Expect = 2e-64, Method: Composition-based stats. Identities = 74/280 (26%), Positives = 109/280 (39%), Gaps = 30/280 (11%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQE 947 + R LG G FGKV + + TG VA+K L + K+E Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKRE 65 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006 I ILR H HII+ + + +VMEY G L DY+ + + + QQ Sbjct 66 IKILRLFIHPHIIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQ 123 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I G+ Y H +HRDL N+LLD+ VK+ DFGL+ + +G + ++ SP Sbjct 124 IISGVEYCHRNMVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDG---HFLKTSCGSPN- 179 Query 1067 WYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 + APE + + DVWS GV LY LL + L Sbjct 180 YAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE---------------NIPNLF 224 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + ++ G P L+ + R T + Sbjct 225 KKIKGGI-YTLPSHLSALARDLIPRMLVVDPMKRITIREI 263 Score = 182 bits (463), Expect = 8e-48, Method: Composition-based stats. Identities = 53/332 (16%), Positives = 101/332 (30%), Gaps = 39/332 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 H K LG G+ V ++ G RV + Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKIAEHKLTGH------------------------RVAI 45 Query 642 KVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 K+L+ + ++ ++ H H+ ++ V + +V EY + G L + Sbjct 46 KILNRRQMRNMEMEEKAKREIKILRLFIHPHIIRLYEVIYTPTDIYVVMEYCKFGELFDY 105 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + E+G + + QQ+ S + Y +VH ++ N+LL +KL+ Sbjct 106 I-VEKGRLQEDEARRIFQQIISGVEYCHRNMVVHRDLKPENLLLDSK-------YNVKLA 157 Query 759 DPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 D G+ + + APE + G + +D W G L + Sbjct 158 DFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYALLCGTLPFD 216 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 P+ + + LP L + L +P +R + R I Sbjct 217 DENIPNLFKKIKGGIYTLPSHLSALARDLIPRMLVVDPMKRITIREIREHQWFQIRLPRY 276 Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 + + + G+ H Sbjct 277 LAVPPPDTAQQAKMIDEDTLQDVVNLGYGKDH 308 >sp|P18161|SPLB_DICDI Dual specificity protein kinase splB OS=Dictyostelium discoideum OX=44689 GN=splB PE=2 SV=2 Length=1155 Score = 243 bits (619), Expect = 2e-64, Method: Composition-based stats. Identities = 74/292 (25%), Positives = 127/292 (43%), Gaps = 34/292 (12%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEI 948 + ++ I+ +GEG F +V + + VA+K LK Q + + +E+ Sbjct 846 YIIDINDIQFIQKVGEGAFSEVWEGWWKGIH------VAIKKLKIIGDEEQFKERFIREV 899 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSIGLAQLL 1001 L+ H++I+ + G C K ++ EY+ GSL + L P+ +L Sbjct 900 QNLKKGNHQNIVMFIGACY----KPACIITEYMAGGSLYNILHNPNSSTPKVKYSFPLVL 955 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 A + G+ +LH+ +HRDL ++N+LLD +KI DFGL++ Sbjct 956 KMATDMALGLLHLHSITIVHRDLTSQNILLDELGNIKISDFGLSREKSREGSMTMTNGGI 1015 Query 1062 DSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 +P W PE K + DV+ F + ++E+LT F +L G Sbjct 1016 CNP-RWRPPELTKNLGHYSEKVDVYCFSLVVWEILTG-------EIPFSDLDGS------ 1061 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 ++ G R P P+ C E+ L+ CWE + + RP F ++ LK + Sbjct 1062 -QASAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKLKEI 1112 Score = 211 bits (536), Expect = 3e-54, Method: Composition-based stats. Identities = 65/307 (21%), Positives = 109/307 (36%), Gaps = 53/307 (17%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 +D +I + +G+G + V+EG + + V +K Sbjct 848 IDINDIQFIQKVGEGAFSEVWEGWWKG--------------------------IHVAIKK 881 Query 644 LD--PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 L F + + +H ++ G C + ++TEY+ G L L Sbjct 882 LKIIGDEEQFKERFIREVQNLKKGNHQNIVMFIGACYK--PACIITEYMAGGSLYNILHN 939 Query 702 ERGHVP-----MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 P + +A +A L +L + +VH ++ +NILL LG IK Sbjct 940 PNSSTPKVKYSFPLVLKMATDMALGLLHLHSITIVHRDLTSQNILLDELG-------NIK 992 Query 757 LSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +SD G+ W PE L S +D + F + EI Sbjct 993 ISDFGLSREKSREGSMTMTNGGICNPRWRPPE-LTKNLGHYSEKVDVYCFSLVVWEIL-T 1050 Query 811 GEAPLQSRSPSE---KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 GE P S+ + + + +PE P+L L +QC +P RP F I+ L Sbjct 1051 GEIPFSDLDGSQASAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKLK 1110 Query 868 RLQPHNL 874 + +N Sbjct 1111 EISWNNP 1117 >sp|P05625|RAF1_CHICK RAF proto-oncogene serine/threonine-protein kinase OS=Gallus gallus OX=9031 GN=RAF1 PE=2 SV=1 Length=647 Score = 235 bits (599), Expect = 2e-64, Method: Composition-based stats. Identities = 79/333 (24%), Positives = 135/333 (41%), Gaps = 35/333 (11%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 + T P+ R + + +S + +G G F Sbjct 305 WSQPKTPVPAQRERAPG----TNTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF 360 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 G V + VAVK LK D P+ ++ E+ +LR H +I+ + G Sbjct 361 GTVYKGKWHG-------DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYM- 412 Query 968 DQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ IHRD+ Sbjct 413 --TKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMK 470 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYAS 1082 + N+ L VKIGDFGLA +V E + W APE ++ F + S Sbjct 471 SNNIFLHEGLTVKIGDFGLATVKSRWSGSQQV-EQPTGSILWMAPEVIRMQDSNPFSFQS 529 Query 1083 DVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 DV+S+G+ LYEL+T + + ++G + +L + C Sbjct 530 DVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYK------------NC 577 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 P + L+ +C + RP F ++ ++ + Sbjct 578 PKAMKRLVADCLKKVREERPLFPQILSSIELLQ 610 Score = 223 bits (567), Expect = 3e-60, Method: Composition-based stats. Identities = 71/367 (19%), Positives = 127/367 (35%), Gaps = 62/367 (17%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 R + N I RG R S + ++ E+ + +G G+ VY+G+ Sbjct 316 RERAPGTNTQEKNKIRPRGQRDSSY--------YWEIEASEVMLSTRIGSGSFGTVYKGK 367 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQ 664 + V +K+L DP+ AF +++ + Sbjct 368 WHGD---------------------------VAVKILKVVDPTPEQFQ-AFRNEVAVLRK 399 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 H ++ G + +VT++ E L L + M + +A+Q A + Y Sbjct 400 TRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778 L KN++H ++ NI L +K+ D G+ G+ E+ I W Sbjct 459 LHAKNIIHRDMKSNNIFLHEGL-------TVKIGDFGLATVKSRWSGSQQVEQPTGSILW 511 Query 779 LAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------ 831 +APE + +N S D + +G L E+ GE P + ++ F + Sbjct 512 MAPEVIRMQDSNPFSFQSDVYSYGIVLYELM-TGELPYSHINNRDQIIFMVGRGYASPDL 570 Query 832 -RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 +L + + L + CL +RP F IL + LQ + + S Sbjct 571 SKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSIELLQHSLPKINRSASEPSLHRASH 630 Query 891 VFHKRYL 897 Sbjct 631 TEDINSC 637 >sp|O81905|SD18_ARATH Receptor-like serine/threonine-protein kinase SD1-8 OS=Arabidopsis thaliana OX=3702 GN=SD18 PE=1 SV=1 Length=850 Score = 239 bits (609), Expect = 2e-64, Method: Composition-based stats. Identities = 73/289 (25%), Positives = 111/289 (38%), Gaps = 20/289 (7%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 LG+G FG V G+ +AVK L Q +K E+ ++ Sbjct 521 MATNNFSNANKLGQGGFGIVYKG-----KLLDGQEMAVKRLSK-TSVQGTDEFKNEVKLI 574 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQI 1007 L H ++++ CC D GEK L+ EY+ SL +L + I Sbjct 575 ARLQHINLVRLLACCVDAGEK--MLIYEYLENLSLDSHLFDKSRNSKLNWQMRFDIINGI 632 Query 1008 CEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 G+ YLH IHRDL A N+LLD KI DFG+A+ R+ Sbjct 633 ARGLLYLHQDSRFRIIHRDLKASNILLDKYMTPKISDFGMARIFGRDETEANTRK-VVGT 691 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELL-THCDSSQSPPTKFLELIGIAQGQMTVLR 1123 + +PE + F SDV+SFGV L E++ + + + L L+G + Sbjct 692 YGYMSPEYAMDGIFSMKSDVFSFGVLLLEIISSKRNKGFYNSDRDLNLLGCVWRNWKEGK 751 Query 1124 LTELLERGERLPRP---DKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 E+++ + C + A RPT +I +L Sbjct 752 GLEIIDPIITDSSSTFRQHEILRCIQIGLLCVQERAEDRPTMSLVILML 800 Score = 226 bits (575), Expect = 5e-60, Method: Composition-based stats. Identities = 56/273 (21%), Positives = 94/273 (34%), Gaps = 47/273 (17%) Query 569 ASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 + L L + F V + + LGQG VY+G+L Sbjct 504 NNTDDLELPLMEFEEVAMATNNFSNANKLGQGGFGIVYKGKLLDGQ-------------- 549 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 + +K L + F L++++ H +L + CV E +++ Sbjct 550 -----------EMAVKRLSKTSVQGTDEFKNEVKLIARLQHINLVRLLACCVDAGEKMLI 598 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENK---NLVHGNVCGRNIL 741 EY+E+ LD L + + + W+M + +A L YL ++H ++ NIL Sbjct 599 YEYLENLSLDSHLFDKSRNSKLNWQMRFDIINGIARGLLYLHQDSRFRIIHRDLKASNIL 658 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAM 795 L + K+SD G+ E V +++PE G S Sbjct 659 LDKYMTP-------KISDFGMARIFGRDETEANTRKVVGTYGYMSPEYAMDGI--FSMKS 709 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 D + FG LLEI S + Sbjct 710 DVFSFGVLLLEIISSKRNKGFYNSDRDLNLLGC 742 >sp|Q9C821|PEK15_ARATH Proline-rich receptor-like protein kinase PERK15 OS=Arabidopsis thaliana OX=3702 GN=PERK15 PE=2 SV=1 Length=509 Score = 231 bits (588), Expect = 2e-64, Method: Composition-based stats. Identities = 77/296 (26%), Positives = 127/296 (43%), Gaps = 29/296 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V G +VA+K LK+ G R ++ EI + ++H H++ Sbjct 149 LGQGGFGYVHRGVL-----VDGTLVAIKQLKSGSGQGERE-FQAEIQTISRVHHRHLVSL 202 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLH---A 1016 G C ++ LV E+VP +L +L + ++ + A +G+AYLH Sbjct 203 LGYCITGAQR--LLVYEFVPNKTLEFHLHEKERPVMEWSKRMKIALGAAKGLAYLHEDCN 260 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ A N+L+D+ K+ DFGLA++ + + R + APE Sbjct 261 PKTIHRDVKAANILIDDSYEAKLADFGLARSSLDTDTHVSTR--IMGTFGYLAPEYASSG 318 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 K SDV+S GV L EL+T P ++ A+ M + L + G Sbjct 319 KLTEKSDVFSIGVVLLELITGRRPVDKSQPFADDDSIVDWAKPLM-IQALNDGNFDGLVD 377 Query 1135 PRPDKCPCEVYHL--MKNC----WETEASFRPTFENLIPILK---TVHEKYQGQAP 1181 PR + ++ + M C A RP ++ + ++ + +G AP Sbjct 378 PRLEN-DFDINEMTRMVACAAASVRHSAKRRPKMSQIVRAFEGNISIDDLTEGAAP 432 Score = 224 bits (570), Expect = 6e-62, Method: Composition-based stats. Identities = 64/275 (23%), Positives = 100/275 (36%), Gaps = 46/275 (17%) Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P + SN ++ +S NL + + LGQG V+ G L Sbjct 111 PKDDSN--NLQQWSSSEIGQNLFTYEDLSKATSNFSNTNLLGQGGFGYVHRGVLVDG--- 165 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 V +K L F +S+V H HL + Sbjct 166 ----------------------TLVAIKQLKSGSGQGEREFQAEIQTISRVHHRHLVSLL 203 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLENK---NL 730 G C+ G + ++V E+V + L+ L +ER + + +M +A A L+YL Sbjct 204 GYCITGAQRLLVYEFVPNKTLEFHLHEKERPVMEWSKRMKIALGAAKGLAYLHEDCNPKT 263 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLP 785 +H +V NIL+ S KL+D G+ +L + V +LAPE Sbjct 264 IHRDVKAANILID-------DSYEAKLADFGLARSSLDTDTHVSTRIMGTFGYLAPEYAS 316 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 G L+ D + G LLE+ G P+ P Sbjct 317 SG--KLTEKSDVFSIGVVLLELI-TGRRPVDKSQP 348 >sp|Q54XX5|Y9849_DICDI Probable serine/threonine-protein kinase DDB_G0278535 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0278535 PE=3 SV=1 Length=848 Score = 239 bits (609), Expect = 2e-64, Method: Composition-based stats. Identities = 76/340 (22%), Positives = 127/340 (37%), Gaps = 24/340 (7%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 + TQ + + + V L+ LG G G Sbjct 482 NKKVTQLSIESLKSNPPNSMDSTGSISSDDLKESLTNLEHWVIDHSELEYTLKLGSGSSG 541 Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 KV Y G+ VAVK LK+ +K+E I+ ++ + ++ + G C Sbjct 542 KVYKGLYK------GKEVAVKVLKSITTQSQLEEFKKEFQIMGSIRSQFMVTFYGACI-- 593 Query 970 GEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHA--QHYIHRDLA 1025 E L +VMEY SL + ++ IG + F Q+ G+ LH +HRD Sbjct 594 -EPKLCMVMEYCSRDSLYHVMNTKKYDIGWDRFFQFTMQMTLGVQCLHNWTPQIVHRDFK 652 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK--FYYASD 1083 + N+L++ D K+ DFGL++ + + +PE + SD Sbjct 653 SLNLLVNEDWECKVSDFGLSRF--NTADNLETLSKIRGTFAYCSPEVAVGNGSLYTTKSD 710 Query 1084 VWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 ++S G+ +EL+T + + S P I + M + G R P P Sbjct 711 IYSIGIVFWELVTRVINGEYSRPYSEYSHIKMDFQIMLNSK------EGLRPTLPQNTPP 764 Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182 + L K C E + RP+ E +I L + +Y + Sbjct 765 GLEALYKQCVNQEQTLRPSCEEIIETLNRLRHEYMSSKTT 804 Score = 181 bits (459), Expect = 2e-45, Method: Composition-based stats. Identities = 63/319 (20%), Positives = 106/319 (33%), Gaps = 53/319 (17%) Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 +L+ L +D E+ LG G+ VY+G + + Sbjct 515 SLTNLEHWVIDHSELEYTLKLGSGSSGKVYKGLYKGK----------------------- 551 Query 635 QELRVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 V +KVL F + +M + + +G C+ P+ MV EY Sbjct 552 ---EVAVKVLKSITTQSQLEEFKKEFQIMGSIRSQFMVTFYGACIE-PKLCMVMEYCSRD 607 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGLAEGT 751 L + ++ + Q+ + L N +VH + N+L+ Sbjct 608 SLYHVMNTKKYDIGWDRFFQFTMQMTLGVQCLHNWTPQIVHRDFKSLNLLVNE------- 660 Query 752 SPFIKLSDPGVGLGALSR-----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 K+SD G+ + + + +PE G + +T D + G E Sbjct 661 DWECKVSDFGLSRFNTADNLETLSKIRGTFAYCSPEVAVGNGSLYTTKSDIYSIGIVFWE 720 Query 807 ICFDGEAPLQSRSPSEKEHFYQR-----------QHRLPEPSCPQLATLTSQCLTYEPTQ 855 + SR SE H + LP+ + P L L QC+ E T Sbjct 721 LVTRVINGEYSRPYSEYSHIKMDFQIMLNSKEGLRPTLPQNTPPGLEALYKQCVNQEQTL 780 Query 856 RPSFRTILRDLTRLQPHNL 874 RPS I+ L RL+ + Sbjct 781 RPSCEEIIETLNRLRHEYM 799 >sp|O81069|Y2899_ARATH Probable leucine-rich repeat receptor-like protein kinase At2g28990 OS=Arabidopsis thaliana OX=3702 GN=At2g28990 PE=1 SV=1 Length=884 Score = 239 bits (610), Expect = 2e-64, Method: Composition-based stats. Identities = 70/307 (23%), Positives = 123/307 (40%), Gaps = 17/307 (6%) Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931 HN + + + + LGEG FG V + E VAVK Sbjct 552 HNSQSESSFTSKKIRFTYSEVQEMTNNFDKALGEGGFGVVYHGFVNVI-----EQVAVKL 606 Query 932 LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP 991 L Q +K E+++L ++H +++ G C++ + L L+ EY+P G L+ +L Sbjct 607 LSQSSS-QGYKHFKAEVELLMRVHHINLVSLVGYCDEG--EHLALIYEYMPNGDLKQHLS 663 Query 992 RHS----IGLAQLLLFAQQICEGMAYLHAQHY---IHRDLAARNVLLDNDRLVKIGDFGL 1044 + L G+ YLH +HRD+ N+LLD K+ DFGL Sbjct 664 GKHGGFVLSWESRLKIVLDAALGLEYLHTGCVPPMVHRDIKTTNILLDQHLQAKLADFGL 723 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP 1104 +++ P G+E +P + PE + SD++SFG+ L E++++ Q Sbjct 724 SRSFPIGNEKNVSTVVAGTP-GYLDPEYYQTNWLTEKSDIYSFGIVLLEIISNRPIIQQS 782 Query 1105 PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 K ++ +T L +++ + L +C ++ RP Sbjct 783 REK-PHIVEWVSFMITKGDLRSIMDPNLHQDYDIGSVWKAIELAMSCVSLSSARRPNMSR 841 Query 1165 LIPILKT 1171 ++ LK Sbjct 842 VVNELKE 848 Score = 212 bits (540), Expect = 2e-55, Method: Composition-based stats. Identities = 68/324 (21%), Positives = 107/324 (33%), Gaps = 60/324 (19%) Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 S T + ++ V + LG+G VY G + V Sbjct 553 NSQSESSFTSKKIRFTYSEVQEMTNNFDKALGEGGFGVVYHGFVNVIE------------ 600 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 +V +K+L S F L+ +V H +L + G C G Sbjct 601 -------------QVAVKLLSQSSSQGYKHFKAEVELLMRVHHINLVSLVGYCDEGEHLA 647 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKNL---VHGNVCGRN 739 ++ EY+ +G L L + G ++W ++ + A L YL + VH ++ N Sbjct 648 LIYEYMPNGDLKQHLSGKHGGFVLSWESRLKIVLDAALGLEYLHTGCVPPMVHRDIKTTN 707 Query 740 ILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPECLPGGANSLST 793 ILL + A KL+D G+ +L PE N L+ Sbjct 708 ILLDQHLQA-------KLADFGLSRSFPIGNEKNVSTVVAGTPGYLDPEYYQT--NWLTE 758 Query 794 AMDKWGFGATLLEICFDGEAPLQSR---SPSEKEHFYQRQHRLPEPSCPQLA-------- 842 D + FG LLEI + QSR E F + L P L Sbjct 759 KSDIYSFGIVLLEIISNRPIIQQSREKPHIVEWVSFMITKGDLRSIMDPNLHQDYDIGSV 818 Query 843 ----TLTSQCLTYEPTQRPSFRTI 862 L C++ +RP+ + Sbjct 819 WKAIELAMSCVSLSSARRPNMSRV 842 >sp|C0LGI2|Y1677_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g67720 OS=Arabidopsis thaliana OX=3702 GN=At1g67720 PE=1 SV=1 Length=929 Score = 240 bits (612), Expect = 2e-64, Method: Composition-based stats. Identities = 71/282 (25%), Positives = 118/282 (42%), Gaps = 18/282 (6%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 + +G G FG V G+ VAVK + AD + E+ +L ++H Sbjct 607 NFSKKVGRGSFGSVYYGRMK-----DGKEVAVK-ITADPSSHLNRQFVTEVALLSRIHHR 660 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGMAY 1013 +++ G CE+ + LV EY+ GSL D+L + L AQ +G+ Y Sbjct 661 NLVPLIGYCEEADRR--ILVYEYMHNGSLGDHLHGSSDYKPLDWLTRLQIAQDAAKGLEY 718 Query 1014 LH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 LH IHRD+ + N+LLD + K+ DFGL++ E + V V + P Sbjct 719 LHTGCNPSIIHRDVKSSNILLDINMRAKVSDFGLSRQTEEDLTH--VSSVAKGTVGYLDP 776 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLRLTELLE 1129 E + SDV+SFGV L+ELL+ + L ++ A+ + + +++ Sbjct 777 EYYASQQLTEKSDVYSFGVVLFELLSGKKPVSAEDFGPELNIVHWARSLIRKGDVCGIID 836 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + V + C E RP + +I ++ Sbjct 837 PCIASNVKIESVWRVAEVANQCVEQRGHNRPRMQEVIVAIQD 878 Score = 221 bits (562), Expect = 5e-58, Method: Composition-based stats. Identities = 57/299 (19%), Positives = 105/299 (35%), Gaps = 61/299 (20%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +G+G+ +VY GR++ V +K+ Sbjct 608 FSKKVGRGSFGSVYYGRMKDGK-------------------------EVAVKITADPSSH 642 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 + F +L+S++ H +L + G C I+V EY+ +G L L + P+ W Sbjct 643 LNRQFVTEVALLSRIHHRNLVPLIGYCEEADRRILVYEYMHNGSLGDHLHGSSDYKPLDW 702 Query 711 --KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 ++ +AQ A L YL N +++H +V NILL + K+SD G+ Sbjct 703 LTRLQIAQDAAKGLEYLHTGCNPSIIHRDVKSSNILLD-------INMRAKVSDFGLSRQ 755 Query 766 ALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 V + +L PE + L+ D + FG L E+ + Sbjct 756 TEEDLTHVSSVAKGTVGYLDPEYYA--SQQLTEKSDVYSFGVVLFELLSGKKPVSAEDFG 813 Query 821 SEKEHFYQRQHRLPEPSCP-----------------QLATLTSQCLTYEPTQRPSFRTI 862 E + + + + ++A + +QC+ RP + + Sbjct 814 PELNIVHWARSLIRKGDVCGIIDPCIASNVKIESVWRVAEVANQCVEQRGHNRPRMQEV 872 >sp|O64782|SD129_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase SD1-29 OS=Arabidopsis thaliana OX=3702 GN=SD129 PE=1 SV=1 Length=805 Score = 238 bits (607), Expect = 2e-64, Method: Composition-based stats. Identities = 70/297 (24%), Positives = 115/297 (39%), Gaps = 17/297 (6%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 + LG+G FG V G+ + VK L A Q Sbjct 474 NFFEMHTIRTATNNFSPSNKLGQGGFGPVYKG-----KLVDGKEIGVKRL-ASSSGQGTE 527 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLA 998 + EI ++ L H ++++ G C D EK L+ E++ SL ++ + + Sbjct 528 EFMNEITLISKLQHRNLVRLLGYCIDGEEK--LLIYEFMVNKSLDIFIFDPCLKFELDWP 585 Query 999 QLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + Q I G+ YLH IHRDL N+LLD+ KI DFGLA+ +G +Y Sbjct 586 KRFNIIQGIARGLLYLHRDSRLRVIHRDLKVSNILLDDRMNPKISDFGLARMF-QGTQYQ 644 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE-LIGI 1114 + + +PE F SD++SFGV + E+++ S+ + L+ Sbjct 645 DNTRRVVGTLGYMSPEYAWAGLFSEKSDIYSFGVLMLEIISGKRISRFIYGDESKGLLAY 704 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + LL+R + C + EA RP ++ +L + Sbjct 705 TWDSWCETGGSNLLDRDLTDTCQAFEVARCVQIGLLCVQHEAVDRPNTLQVLSMLTS 761 Score = 229 bits (585), Expect = 1e-61, Method: Composition-based stats. Identities = 56/256 (22%), Positives = 98/256 (38%), Gaps = 45/256 (18%) Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 R +N ++ R + + LGQG VY+G+L Sbjct 467 RQDVSGVNFFEMHTIRTATNNFSPSNKLGQGGFGPVYKGKL------------------- 507 Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 V G++ G +K L S F +L+S++ H +L + G C+ G E +++ Sbjct 508 VDGKEIG------VKRLASSSGQGTEEFMNEITLISKLQHRNLVRLLGYCIDGEEKLLIY 561 Query 688 EYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILL 742 E++ + LD+++ + W + + Q +A L YL ++H ++ NILL Sbjct 562 EFMVNKSLDIFIFDPCLKFELDWPKRFNIIQGIARGLLYLHRDSRLRVIHRDLKVSNILL 621 Query 743 ARLGLAEGTSPFIKLSDPGVGL----GALSREER--VERIPWLAPECLPGGANSLSTAMD 796 K+SD G+ R V + +++PE G S D Sbjct 622 D-------DRMNPKISDFGLARMFQGTQYQDNTRRVVGTLGYMSPEYAWAGL--FSEKSD 672 Query 797 KWGFGATLLEICFDGE 812 + FG +LEI Sbjct 673 IYSFGVLMLEIISGKR 688 >sp|Q8T2I8|SEPA_DICDI Serine/threonine-protein kinase sepA OS=Dictyostelium discoideum OX=44689 GN=sepA PE=2 SV=1 Length=1167 Score = 242 bits (618), Expect = 2e-64, Method: Composition-based stats. Identities = 73/267 (27%), Positives = 124/267 (46%), Gaps = 28/267 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIK 961 +G+G FG V Y + G+ VA+K + P+ + G EID+L+ L H +I+K Sbjct 24 IGKGGFGTV----YQGLDIEDGDFVAIKQINLTKIPKDQLQGIMNEIDLLKNLNHANIVK 79 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 Y + + +L +V+EYV GSL + + + ++ +Q+ EG+ YLH Q + Sbjct 80 YIKYV--KTKDNLYIVLEYVENGSLSGIIKKFGKFPETLVCVYIRQVLEGLVYLHEQGVV 137 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ N+L + +K+ DFG+A + +W APE ++ Sbjct 138 HRDIKGANILTTKEGKIKLADFGVATKFDD-----TSAAAVVGTPYWMAPEIIELNGATT 192 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SD+WS G T+ ELLT SPP L GQM L + + + P P+ Sbjct 193 KSDIWSVGCTVIELLTG-----SPPYYDL-------GQMPAL---FRIVQDDCPPLPEGI 237 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIP 1167 + + C++ + + R + + L+ Sbjct 238 SPPLKDWLMQCFQKDPNLRISAQKLLK 264 Score = 204 bits (520), Expect = 3e-52, Method: Composition-based stats. Identities = 64/280 (23%), Positives = 101/280 (36%), Gaps = 41/280 (15%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH--HDI 651 +G+G VY+G +G V +K ++ + D Sbjct 23 VIGKGGFGTVYQGLDIEDGDF------------------------VAIKQINLTKIPKDQ 58 Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711 L+ ++H ++ +V EYVE+G L +++ G P Sbjct 59 LQGIMNEIDLLKNLNHANIVKYIKYVKTKDNLYIVLEYVENGSLSGIIKK-FGKFPETLV 117 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--GALSR 769 V +Q+ L YL + +VH ++ G NIL + G IKL+D GV S Sbjct 118 CVYIRQVLEGLVYLHEQGVVHRDIKGANILTTKEG-------KIKLADFGVATKFDDTSA 170 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR--SPSEKEHFY 827 V W+APE + +T D W G T++E+ G P P+ Sbjct 171 AAVVGTPYWMAPEIIELNGA--TTKSDIWSVGCTVIELL-TGSPPYYDLGQMPALFRIVQ 227 Query 828 QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 LPE P L QC +P R S + +L+ Sbjct 228 DDCPPLPEGISPPLKDWLMQCFQKDPNLRISAQKLLKHKW 267 >sp|Q9FZB1|Y5188_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g51880 OS=Arabidopsis thaliana OX=3702 GN=At1g51880 PE=2 SV=1 Length=872 Score = 239 bits (609), Expect = 2e-64, Method: Composition-based stats. Identities = 66/284 (23%), Positives = 119/284 (42%), Gaps = 18/284 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R LG+G FG V + T VAVK L Q +K E+++L + Sbjct 564 MTNNFERVLGKGGFGTVYHGNLEDT------QVAVKMLSH-SSAQGYKEFKAEVELLLRV 616 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEG 1010 +H +++ G C+D +L L+ EY+ G L++ + + + A + +G Sbjct 617 HHRNLVGLVGYCDDGD--NLALIYEYMANGDLKENMSGKRGGNVLTWENRMQIAVEAAQG 674 Query 1011 MAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH +HRD+ N+LL+ K+ DFGL+++ P E + +P + Sbjct 675 LEYLHNGCTPPMVHRDVKTTNILLNERYGAKLADFGLSRSFPVDGESHVSTVVAGTP-GY 733 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 PE + SDV+SFGV L E++T+ + + + +T + + Sbjct 734 LDPEYYRTNWLSEKSDVYSFGVVLLEIVTNQPVTDKTRER-THINEWVGSMLTKGDIKSI 792 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 L+ ++ L C ++ RPT +++ L Sbjct 793 LDPKLMGDYDTNGAWKIVELALACVNPSSNRRPTMAHVVTELNE 836 Score = 213 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 78/374 (21%), Positives = 131/374 (35%), Gaps = 70/374 (19%) Query 515 VLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTL 574 L+G + P + + + L F + R + + +N I+ R Sbjct 501 TLKGKSKKVPMIPIVASVAGVFALLVILAIFFVVRRKNGESNKGTNPSIITKER------ 554 Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 ++++ V + LG+G VY G L Sbjct 555 ---RITYPEVLKMTNNFERVLGKGGFGTVYHGNL-------------------------- 585 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 ++ +V +K+L S F L+ +V H +L + G C G ++ EY+ +G Sbjct 586 EDTQVAVKMLSHSSAQGYKEFKAEVELLLRVHHRNLVGLVGYCDDGDNLALIYEYMANGD 645 Query 695 LDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAE 749 L + +RG + W +M +A + A L YL N +VH +V NILL A Sbjct 646 LKENMSGKRGGNVLTWENRMQIAVEAAQGLEYLHNGCTPPMVHRDVKTTNILLNERYGA- 704 Query 750 GTSPFIKLSDPGVGLG-ALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 KL+D G+ + E V +L PE N LS D + FG Sbjct 705 ------KLADFGLSRSFPVDGESHVSTVVAGTPGYLDPEYYRT--NWLSEKSDVYSFGVV 756 Query 804 LLEICFDGEAPLQSR---SPSEKEHFYQRQHRLPEPSCPQL------------ATLTSQC 848 LLEI + ++R +E + + P+L L C Sbjct 757 LLEIVTNQPVTDKTRERTHINEWVGSMLTKGDIKSILDPKLMGDYDTNGAWKIVELALAC 816 Query 849 LTYEPTQRPSFRTI 862 + +RP+ + Sbjct 817 VNPSSNRRPTMAHV 830 >sp|Q5E9Y0|CDK2_BOVIN Cyclin-dependent kinase 2 OS=Bos taurus OX=9913 GN=CDK2 PE=2 SV=1 Length=298 Score = 223 bits (569), Expect = 2e-64, Method: Composition-based stats. Identities = 69/289 (24%), Positives = 122/289 (42%), Gaps = 30/289 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ Sbjct 1 MENFQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICE 1009 L H +I+K E L LV E++ L+ ++ I L + + Q+ + Sbjct 57 ELNHPNIVKLLDVI--HTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQ 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 G+A+ H+ +HRDL +N+L++ D +K+ DFGLA+A R +++ A Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINADGSIKLADFGLARAFGVP---VRTYTHEVVTLWYRA 170 Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL- 1127 PE L K+Y A D+WS G E++T ++ +L I + T + Sbjct 171 PEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPG-DSEIDQLFRIFRTLGTPDEVVWPG 229 Query 1128 --LERGERLPRPDKCPCEV-----------YHLMKNCWETEASFRPTFE 1163 + P + L+ + + R + + Sbjct 230 VTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAK 278 Score = 171 bits (432), Expect = 6e-46, Method: Composition-based stats. Identities = 47/266 (18%), Positives = 95/266 (36%), Gaps = 40/266 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 + ++ +G+GT VY+ + ++ G V LK Sbjct 1 MENFQKVEKIGEGTYGVVYKAKNKLTGE------------------------VVALKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 LD + SL+ +++H ++ + V + +V E++ H L ++ Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-HQDLKKFMDASA 95 Query 704 -GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 +P+ QL L++ + ++H ++ +N+L+ G IKL+D G+ Sbjct 96 LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINADG-------SIKLADFGL 148 Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + + APE L G STA+D W G E+ Sbjct 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKY-YSTAVDIWSLGCIFAEMVTRRALFPGDS 207 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ E P + ++ Sbjct 208 EIDQLFRIFRTLGTPDEVVWPGVTSM 233 >sp|Q6H7U5|CIPKQ_ORYSJ CBL-interacting protein kinase 26 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK26 PE=2 SV=1 Length=493 Score = 230 bits (586), Expect = 2e-64, Method: Composition-based stats. Identities = 60/275 (22%), Positives = 112/275 (41%), Gaps = 26/275 (9%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDIL 951 + R LG+G+F KV N +G+ VA+K + + + K+EI I+ Sbjct 9 MDRYEIGRQLGQGNFAKVYY----ARNLTSGQAVAIKMIDKEKVTRVGLMVQIKREISIM 64 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011 R + H +I++ + + + V+EY G L + + + Q+ G+ Sbjct 65 RLVKHPNILQLFEVMASKSK--IYFVLEYAKGGELFKKISKGKFSEDVARRYFHQLISGI 122 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 Y H++ HRDL N+LLD + +K+ DFGL+ A+ E + + + APE Sbjct 123 DYCHSRGVYHRDLKPENLLLDENESLKVSDFGLS-ALSESKRHDGLLHTTCGTPAYVAPE 181 Query 1072 CLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 L + +D+WS GV L+ L++ ++ + + + Sbjct 182 VLSRRGYDGAKADIWSCGVILFVLVSGYLPFHDT---------------NLIEMYRKIAK 226 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 E P E+ L+ + + S R + + Sbjct 227 AE-YKCPRSFSAELKDLLYKILDPDPSTRISIPKI 260 Score = 187 bits (476), Expect = 9e-50, Method: Composition-based stats. Identities = 55/296 (19%), Positives = 95/296 (32%), Gaps = 45/296 (15%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 + LGQG VY R G V +K Sbjct 6 TILMDRYEIGRQLGQGNFAKVYYARNLTSGQ------------------------AVAIK 41 Query 643 VLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 ++D + + + S+M V H ++ + V + V EY + G L + Sbjct 42 MIDKEKVTRVGLMVQIKREISIMRLVKHPNILQLFEVMASKSKIYFVLEYAKGGELFKKI 101 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 +G QL S + Y ++ + H ++ N+LL + +K+SD Sbjct 102 --SKGKFSEDVARRYFHQLISGIDYCHSRGVYHRDLKPENLLLDE-------NESLKVSD 152 Query 760 PGVGLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ + S+ ++APE L D W G L + G Sbjct 153 FGLSALSESKRHDGLLHTTCGTPAYVAPEVLSRRGYD-GAKADIWSCGVIL-FVLVSGYL 210 Query 814 PLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 P + E + +++ P +L L + L +P+ R S I R Sbjct 211 PFHDTNLIEMYRKIAKAEYKCPRSFSAELKDLLYKILDPDPSTRISIPKIKRSAWY 266 >sp|C0LGG3|Y5182_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g51820 OS=Arabidopsis thaliana OX=3702 GN=At1g51820 PE=1 SV=1 Length=885 Score = 239 bits (610), Expect = 3e-64, Method: Composition-based stats. Identities = 65/295 (22%), Positives = 121/295 (41%), Gaps = 17/295 (6%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 + + R LG+G FG V + T E VAVK L Q Sbjct 565 NRRFSYSQVVIMTNNFQRILGKGGFGMVYHGFVNGT-----EQVAVKILSHSSS-QGYKQ 618 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQ 999 +K E+++L ++H++++ G C++ +L L+ EY+ G L++++ R + Sbjct 619 FKAEVELLLRVHHKNLVGLVGYCDEGD--NLALIYEYMANGDLKEHMSGTRNRFILNWGT 676 Query 1000 LLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 L + +G+ YLH +HRD+ N+LL+ K+ DFGL+++ E + Sbjct 677 RLKIVIESAQGLEYLHNGCKPPMVHRDVKTTNILLNEHFEAKLADFGLSRSFLIEGETHV 736 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 +P + PE + SDV+SFG+ L E++T+ K + Sbjct 737 STVVAGTP-GYLDPEYHRTNWLTEKSDVYSFGILLLEIITNRHVIDQSREK-PHIGEWVG 794 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +T + +++ + L +C ++ RPT ++ L Sbjct 795 VMLTKGDIQSIMDPSLNEDYDSGSVWKAVELAMSCLNHSSARRPTMSQVVIELNE 849 Score = 211 bits (536), Expect = 6e-55, Method: Composition-based stats. Identities = 74/337 (22%), Positives = 115/337 (34%), Gaps = 61/337 (18%) Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 P + S+ + R + + T N + S+ +V LG+G VY G + Sbjct 542 PPSYMQASDGRLPRSSEPAIVTKN-RRFSYSQVVIMTNNFQRILGKGGFGMVYHGFVNGT 600 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 +V +K+L S F L+ +V H +L Sbjct 601 E-------------------------QVAVKILSHSSSQGYKQFKAEVELLLRVHHKNLV 635 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN-- 727 + G C G ++ EY+ +G L + R + W ++ + + A L YL N Sbjct 636 GLVGYCDEGDNLALIYEYMANGDLKEHMSGTRNRFILNWGTRLKIVIESAQGLEYLHNGC 695 Query 728 -KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL-SREERV-----ERIPWLA 780 +VH +V NILL A KL+D G+ L E V +L Sbjct 696 KPPMVHRDVKTTNILLNEHFEA-------KLADFGLSRSFLIEGETHVSTVVAGTPGYLD 748 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR---SPSEKEHFYQRQHRLPEPS 837 PE N L+ D + FG LLEI + QSR E + + Sbjct 749 PEY--HRTNWLTEKSDVYSFGILLLEIITNRHVIDQSREKPHIGEWVGVMLTKGDIQSIM 806 Query 838 CPQL------------ATLTSQCLTYEPTQRPSFRTI 862 P L L CL + +RP+ + Sbjct 807 DPSLNEDYDSGSVWKAVELAMSCLNHSSARRPTMSQV 843 >sp|A4K2Q5|STK4_OTOGA Serine/threonine-protein kinase 4 OS=Otolemur garnettii OX=30611 GN=STK4 PE=3 SV=1 Length=487 Score = 230 bits (586), Expect = 3e-64, Method: Composition-based stats. Identities = 67/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 ++ C R T L+ Sbjct 250 WSDNFTDFVRQCLVKSPDQRATATQLLQ 277 Score = 202 bits (515), Expect = 6e-55, Method: Composition-based stats. Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L + S + ++ L LG+G+ +VY+ + G Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K + + S+M Q H+ +G + + +V EY G + Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + Q L YL +H ++ NILL G Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163 Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D GV R + W+APE + + D W G T +E+ +G Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220 Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P P R PE QCL P QR + +L+ Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVRQCLVKSPDQRATATQLLQHPF 280 >sp|O22833|LRK54_ARATH L-type lectin-domain containing receptor kinase V.4 OS=Arabidopsis thaliana OX=3702 GN=LECRK54 PE=2 SV=1 Length=658 Score = 234 bits (597), Expect = 3e-64, Method: Composition-based stats. Identities = 73/317 (23%), Positives = 130/317 (41%), Gaps = 17/317 (5%) Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920 +I + + + + K + LG+G FG+V + T Sbjct 298 SIFFYRRHKKVKEVLEEWEIQCGPHRFAYKELFKATKGFKQLLGKGGFGQV----FKGTL 353 Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 G+ +AVK + D Q + EI + L H+++++ +G C + E L LV ++ Sbjct 354 PGSDAEIAVKRISHD-SKQGMQEFLAEISTIGRLRHQNLVRLQGYCRYKEE--LYLVYDF 410 Query 981 VPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQHY---IHRDLAARNVLLDN 1033 +P GSL YL + + Q + I + YLH + IHRD+ NVL+D+ Sbjct 411 MPNGSLDKYLYHRANQEQLTWNQRFKIIKDIASALCYLHHEWVQVVIHRDIKPANVLIDH 470 Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 ++GDFGLAK +G++ R G ++ APE ++ + +DV++FG+ + E Sbjct 471 QMNARLGDFGLAKLYDQGYDPQTSRVAG--TFWYIAPELIRSGRATTGTDVYAFGLFMLE 528 Query 1094 LLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152 + + + + L + E + G R + V L C Sbjct 529 VSCGRRLIERRTASDEVVLAEWTLKCWENGDILEAVNDGIRHEDNREQLELVLKLGVLCS 588 Query 1153 ETEASFRPTFENLIPIL 1169 + RP ++ IL Sbjct 589 HQAVAIRPDMSKVVQIL 605 Score = 207 bits (527), Expect = 5e-55, Method: Composition-based stats. Identities = 52/284 (18%), Positives = 99/284 (35%), Gaps = 64/284 (23%) Query 582 HRVDQKEITQLSH-----LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 HR KE+ + + LG+G V++G L G + Sbjct 322 HRFAYKELFKATKGFKQLLGKGGFGQVFKGTL------------------------PGSD 357 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 + +K + F S + ++ H +L + G C E +V +++ +G LD Sbjct 358 AEIAVKRISHDSKQGMQEFLAEISTIGRLRHQNLVRLQGYCRYKEELYLVYDFMPNGSLD 417 Query 697 VWL--RRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGT 751 +L R + + + + + +ASAL YL + + ++H ++ N+L+ Sbjct 418 KYLYHRANQEQLTWNQRFKIIKDIASALCYLHHEWVQVVIHRDIKPANVLIDHQ------ 471 Query 752 SPFIKLSDPGVGLGA-----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 +L D G+ ++APE + G +T D + FG +LE Sbjct 472 -MNARLGDFGLAKLYDQGYDPQTSRVAGTFWYIAPELIRSGRA--TTGTDVYAFGLFMLE 528 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLT 850 + + + E LA T +C Sbjct 529 VSCGRRLIERRTASDEVV----------------LAEWTLKCWE 556 >sp|Q9LK35|THE1_ARATH Receptor-like protein kinase THESEUS 1 OS=Arabidopsis thaliana OX=3702 GN=THE1 PE=1 SV=1 Length=855 Score = 238 bits (608), Expect = 3e-64, Method: Composition-based stats. Identities = 75/300 (25%), Positives = 122/300 (41%), Gaps = 20/300 (7%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 + + LG G FG+V + G VAVK Q Sbjct 493 HLGRCFMFQEIMDATNKFDESSLLGVGGFGRVYKGTLE-----DGTKVAVKRGNPR-SEQ 546 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIG 996 + ++ EI++L L H H++ G C+++ E + LV EY+ G LR +L + Sbjct 547 GMAEFRTEIEMLSKLRHRHLVSLIGYCDERSE--MILVYEYMANGPLRSHLYGADLPPLS 604 Query 997 LAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 Q L G+ YLH +Q IHRD+ N+LLD + + K+ DFGL+K P + Sbjct 605 WKQRLEICIGAARGLHYLHTGASQSIIHRDVKTTNILLDENLVAKVADFGLSKTGPSLDQ 664 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 + V + PE + + SDV+SFGV L E+L C P E + Sbjct 665 TH-VSTAVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLMEVL--CCRPALNPVLPREQVN 721 Query 1114 IAQGQMTVLR---LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 IA+ M + L ++++ + + C RP+ +++ L+ Sbjct 722 IAEWAMAWQKKGLLDQIMDSNLTGKVNPASLKKFGETAEKCLAEYGVDRPSMGDVLWNLE 781 Score = 226 bits (577), Expect = 3e-60, Method: Composition-based stats. Identities = 66/348 (19%), Positives = 116/348 (33%), Gaps = 61/348 (18%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + + S LG G VY+G L +V +K Sbjct 506 ATNKFDESSLLGVGGFGRVYKGTLEDG-------------------------TKVAVKRG 540 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER- 703 +P F ++S++ H HL + G C E I+V EY+ +GPL L Sbjct 541 NPRSEQGMAEFRTEIEMLSKLRHRHLVSLIGYCDERSEMILVYEYMANGPLRSHLYGADL 600 Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + ++ + A L YL +++++H +V NILL + K++D Sbjct 601 PPLSWKQRLEICIGAARGLHYLHTGASQSIIHRDVKTTNILLDE-------NLVAKVADF 653 Query 761 GVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA- 813 G+ S ++ +L PE L+ D + FG L+E+ A Sbjct 654 GLSKTGPSLDQTHVSTAVKGSFGYLDPEYFR--RQQLTEKSDVYSFGVVLMEVLCCRPAL 711 Query 814 ----PLQSRSPSEKEHFYQRQHRLPEPSCPQLA------------TLTSQCLTYEPTQRP 857 P + + +E +Q++ L + L +CL RP Sbjct 712 NPVLPREQVNIAEWAMAWQKKGLLDQIMDSNLTGKVNPASLKKFGETAEKCLAEYGVDRP 771 Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 S +L +L + PD +++ + D Sbjct 772 SMGDVLWNLEYALQLEETSSALMEPDDNSTNHIPGIPMAPMEPFDNSM 819 >sp|A4K2P5|STK4_COLGU Serine/threonine-protein kinase 4 OS=Colobus guereza OX=33548 GN=STK4 PE=3 SV=1 Length=487 Score = 229 bits (585), Expect = 3e-64, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLQSTLKGLEYLHFMRK 145 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 +K C R T L+ Sbjct 250 WSDNFTDFVKQCLVKSPEQRATATQLLQ 277 Score = 201 bits (512), Expect = 2e-54, Method: Composition-based stats. Identities = 60/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L + S + ++ L LG+G+ +VY+ + G Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K + + S+M Q H+ +G + + +V EY G + Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + V Q L YL +H ++ NILL G Sbjct 111 SDIIRLRNKTLTEDEIATVLQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163 Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D GV R + W+APE + + D W G T +E+ +G Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220 Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P P R PE QCL P QR + +L+ Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPF 280 >sp|Q0JI49|CIPKB_ORYSJ CBL-interacting protein kinase 11 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK11 PE=2 SV=1 Length=502 Score = 230 bits (586), Expect = 4e-64, Method: Composition-based stats. Identities = 62/269 (23%), Positives = 109/269 (41%), Gaps = 31/269 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960 LG+G F KV N TG+ VA+K + D + K+EI I+R + H +++ Sbjct 18 LGQGTFAKVYY----ARNLTTGQAVAIKMINKDKVMKVGLMEQIKREISIMRLVKHPNVL 73 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHY 1019 + + + + V+EY G L + + + + + Q+ + Y H++ Sbjct 74 QLFEVMASKSK--IYFVLEYAKGGELFNKIAKEGKLSEDSARRYFHQLINAVDYCHSRGV 131 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 HRDL N+LLD + +K+ DFGL+ + + +P + APE L + Sbjct 132 YHRDLKPENLLLDENENLKVSDFGLSALAESKRQDGLLHTTCGTPA-YVAPEVLSRKGYD 190 Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP--R 1136 +DVWS GV L+ L+ P L E+ + R Sbjct 191 GAKADVWSCGVILFVLVAGYLPFHDP------------------NLIEMYRKICRADFRC 232 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P E+ L+ +++ S R + + Sbjct 233 PRYFSAELKDLIHKILDSDPSTRISIPRI 261 Score = 186 bits (473), Expect = 3e-49, Method: Composition-based stats. Identities = 58/287 (20%), Positives = 94/287 (33%), Gaps = 44/287 (15%) Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH-- 649 LGQGT VY R G V +K+++ Sbjct 15 GKQLGQGTFAKVYYARNLTTGQ------------------------AVAIKMINKDKVMK 50 Query 650 -DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 + S+M V H ++ + V + V EY + G L + +E G + Sbjct 51 VGLMEQIKREISIMRLVKHPNVLQLFEVMASKSKIYFVLEYAKGGELFNKIAKE-GKLSE 109 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 QL +A+ Y ++ + H ++ N+LL + +K+SD G+ A S Sbjct 110 DSARRYFHQLINAVDYCHSRGVYHRDLKPENLLLDE-------NENLKVSDFGLSALAES 162 Query 769 R------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + ++APE L D W G L + G P + E Sbjct 163 KRQDGLLHTTCGTPAYVAPEVLSRKGYD-GAKADVWSCGVIL-FVLVAGYLPFHDPNLIE 220 Query 823 K-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + R P +L L + L +P+ R S I R Sbjct 221 MYRKICRADFRCPRYFSAELKDLIHKILDSDPSTRISIPRIKRSTWY 267 >sp|A4K2S1|STK4_LEMCA Serine/threonine-protein kinase 4 OS=Lemur catta OX=9447 GN=STK4 PE=3 SV=1 Length=487 Score = 229 bits (585), Expect = 4e-64, Method: Composition-based stats. Identities = 67/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 87 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 ++ C R T L+ Sbjct 250 WSDNFMDFVRQCLVKSPDQRATATQLLQ 277 Score = 202 bits (515), Expect = 8e-55, Method: Composition-based stats. Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L + S + ++ L LG+G+ +VY+ + G Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K + + S+M Q H+ +G + + +V EY G + Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 110 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + Q L YL +H ++ NILL G Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163 Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D GV R + W+APE + + D W G T +E+ +G Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220 Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P P R PE QCL P QR + +L+ Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFMDFVRQCLVKSPDQRATATQLLQHPF 280 >sp|Q39008|M3K1_ARATH Mitogen-activated protein kinase kinase kinase 1 OS=Arabidopsis thaliana OX=3702 GN=MEKK1 PE=1 SV=2 Length=608 Score = 233 bits (593), Expect = 4e-64, Method: Composition-based stats. Identities = 76/278 (27%), Positives = 122/278 (44%), Gaps = 34/278 (12%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQ---EIDILR 952 +K + LG G FG V G G+ AVK + D G Q + +Q EI +L Sbjct 333 WQKGQLLGRGSFGSVYEGI-----SGDGDFFAVKEVSLLDQGSQAQECIQQLEGEIKLLS 387 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 L H++I++Y+G +D +L + +E V GSL R+ + + + L+ +QI +G+ Sbjct 388 QLQHQNIVRYRGTAKDGS--NLYIFLELVTQGSLLKLYQRYQLRDSVVSLYTRQILDGLK 445 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 YLH + +IHRD+ N+L+D + VK+ DFGLAK + FW APE Sbjct 446 YLHDKGFIHRDIKCANILVDANGAVKLADFGLAKVSKFNDI-----KSCKGTPFWMAPEV 500 Query 1073 LKEY---KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 + + +D+WS G T+ E+ T I + ++ + Sbjct 501 INRKDSDGYGSPADIWSLGCTVLEMCTG---------------QIPYSDLEPVQALFRIG 545 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 RG PD + + C + RPT L+ Sbjct 546 RGTLPEVPDTLSLDARLFILKCLKVNPEERPTAAELLN 583 Score = 194 bits (493), Expect = 5e-51, Method: Composition-based stats. Identities = 55/282 (20%), Positives = 100/282 (35%), Gaps = 35/282 (12%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + LG+G+ +VYEG +E + D+ + Sbjct 335 KGQLLGRGSFGSVYEGISGDGDFFAVKEVSLLDQGSQA--------------------QE 374 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 L+SQ+ H ++ G G + E V G L +R + + Sbjct 375 CIQQLEGEIKLLSQLQHQNIVRYRGTAKDGSNLYIFLELVTQGSLLKL--YQRYQLRDSV 432 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA--LS 768 + +Q+ L YL +K +H ++ NIL+ + +KL+D G+ + Sbjct 433 VSLYTRQILDGLKYLHDKGFIHRDIKCANILVD-------ANGAVKLADFGLAKVSKFND 485 Query 769 REERVERIPWLAPECL-PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 + W+APE + ++ + D W G T+LE+C G+ P P + Sbjct 486 IKSCKGTPFWMAPEVINRKDSDGYGSPADIWSLGCTVLEMC-TGQIPYSDLEPVQALFRI 544 Query 828 QRQ--HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 R +P+ +CL P +RP+ +L Sbjct 545 GRGTLPEVPDTLSLDARLFILKCLKVNPEERPTAAELLNHPF 586 >sp|Q54RZ7|Y1199_DICDI Probable serine/threonine-protein kinase DDB_G0282895 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0282895 PE=3 SV=1 Length=1634 Score = 243 bits (620), Expect = 4e-64, Method: Composition-based stats. Identities = 72/288 (25%), Positives = 131/288 (45%), Gaps = 26/288 (9%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 A T + L+ ++ LGEG +V + G+ VAVK + Sbjct 1365 QAFAHTQIEESELQILQFLGEGALAEVHKGIWK------GKEVAVKIFNEGSFSFRLEDF 1418 Query 945 KQEIDILRTLYHEHIIKYKGCCE--DQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLL 1001 +E+ IL + H +++K KG C + + +V E + G+L + + ++ + L ++ Sbjct 1419 LKEVAILGLISHPNLLKLKGACIAPRSHKSTFMIVTELMHKGTLLEVINKNKPLSLEDII 1478 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 +A + +G+AYLH+ +IHRD+ A N+L+D + K+GDFGL++ + Sbjct 1479 KYALSVAQGLAYLHSVDFIHRDIKAANILVDKNNNAKVGDFGLSRVIDNNFN----MTAV 1534 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 W +PECL + ASDV+S+G+ L+EL T P + ++ +A+ Sbjct 1535 AGTPKWESPECLMGEAYTSASDVYSYGMMLFELATG----DEPFLEIQSIVELAR----- 1585 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + ++ + P + L+K+C RPT +I L Sbjct 1586 ----SVCDKKLKPKISSSVPNFISSLIKDCLHNSPKKRPTMNQIIQKL 1629 Score = 201 bits (512), Expect = 4e-51, Method: Composition-based stats. Identities = 58/297 (20%), Positives = 119/297 (40%), Gaps = 47/297 (16%) Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 + ++++ E+ L LG+G V++G + + Sbjct 1367 FAHTQIEESELQILQFLGEGALAEVHKGIWKGK--------------------------E 1400 Query 639 VVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCV----RGPENIMVTEYVEHG 693 V +K+ + L F + +++ +SH +L + G C+ ++VTE + G Sbjct 1401 VAVKIFNEGSFSFRLEDFLKEVAILGLISHPNLLKLKGACIAPRSHKSTFMIVTELMHKG 1460 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L + + + + + + A +A L+YL + + +H ++ NIL+ + + Sbjct 1461 TLLEVINKNK-PLSLEDIIKYALSVAQGLAYLHSVDFIHRDIKAANILVDK-------NN 1512 Query 754 FIKLSDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K+ D G+ + W +PECL G A ++A D + +G L E+ Sbjct 1513 NAKVGDFGLSRVIDNNFNMTAVAGTPKWESPECLMGEA--YTSASDVYSYGMMLFELATG 1570 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCP---QLATLTSQCLTYEPTQRPSFRTILR 864 E L+ +S E + P+ S +++L CL P +RP+ I++ Sbjct 1571 DEPFLEIQSIVELARSVCDKKLKPKISSSVPNFISSLIKDCLHNSPKKRPTMNQIIQ 1627 >sp|Q6R2J8|SRF8_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 8 OS=Arabidopsis thaliana OX=3702 GN=SRF8 PE=1 SV=1 Length=703 Score = 235 bits (599), Expect = 4e-64, Method: Composition-based stats. Identities = 71/299 (24%), Positives = 125/299 (42%), Gaps = 25/299 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG G+V + G+++A+K + A Q + + + + L H +I+ Sbjct 401 IGEGSLGRVYRAEF-----PNGKIMAIKKIDNAALSLQEEDNFLEAVSNMSRLRHPNIVP 455 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHA 1016 G C + G++ LV EYV G+L D L + ++ + A + + YLH Sbjct 456 LAGYCTEHGQR--LLVYEYVGNGNLDDTLHTNDDRSMNLTWNARVKVALGTAKALEYLHE 513 Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +HR+ + N+LLD + + D GLA P +V + APE Sbjct 514 VCLPSIVHRNFKSANILLDEELNPHLSDSGLAALTPNTER--QVSTQVVGSFGYSAPEFA 571 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQM-TVLRLTELLERG 1131 + SDV++FGV + ELLT S T+ L+ A Q+ + L+++++ Sbjct 572 LSGIYTVKSDVYTFGVVMLELLTGRKPLDSSRTRAEQSLVRWATPQLHDIDALSKMVDPS 631 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE-----KYQGQAPSVFS 1185 P K ++ C + E FRP ++ L + + K + + FS Sbjct 632 LNGMYPAKSLSRFADIIALCIQPEPEFRPPMSEVVQQLVRLVQRASVVKRRSSDDTGFS 690 Score = 197 bits (501), Expect = 2e-51, Method: Composition-based stats. Identities = 74/357 (21%), Positives = 127/357 (36%), Gaps = 65/357 (18%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 SP T + +S +V +Q + +G+G+ VY Sbjct 376 SPITASQYTVSSLQVATNSFSQENIIGEGSLGRVYRA----------------------- 412 Query 630 GRDRGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 + + +K +D + + F E S MS++ H ++ + G C + ++V Sbjct 413 --EFPNGKIMAIKKIDNAALSLQEEDNFLEAVSNMSRLRHPNIVPLAGYCTEHGQRLLVY 470 Query 688 EYVEHGPLDVWLRRERG---HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNIL 741 EYV +G LD L ++ ++ VA A AL YL ++VH N NIL Sbjct 471 EYVGNGNLDDTLHTNDDRSMNLTWNARVKVALGTAKALEYLHEVCLPSIVHRNFKSANIL 530 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMD 796 L LSD G+ + E +V + APE G + D Sbjct 531 LDEELNPH-------LSDSGLAALTPNTERQVSTQVVGSFGYSAPEFALSGI--YTVKSD 581 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS------------------C 838 + FG +LE+ + SR+ +E+ +L + Sbjct 582 VYTFGVVMLELLTGRKPLDSSRTRAEQSLVRWATPQLHDIDALSKMVDPSLNGMYPAKSL 641 Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895 + A + + C+ EP RP +++ L RL + D+ S T H+ Sbjct 642 SRFADIIALCIQPEPEFRPPMSEVVQQLVRLVQRASVVKRRSSDDTGFSYRTPEHEH 698 >sp|Q55GG4|Y9847_DICDI Probable serine/threonine-protein kinase DDB_G0267686 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0267686 PE=3 SV=1 Length=2230 Score = 243 bits (621), Expect = 4e-64, Method: Composition-based stats. Identities = 67/301 (22%), Positives = 125/301 (42%), Gaps = 24/301 (8%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 + + + LGEG KV + + VAVK L+++ Q + Sbjct 1937 MNFNNWAIDGEEIVFLNKLGEGTSAKVYRATWR------NQEVAVKVLRSEPESQKLLDF 1990 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLF 1003 +E++I+ +L H++ + G D + ++MEY +L + + + + F Sbjct 1991 LKELEIMSSLRSPHVVYFYGMVLDP---KICMIMEYCSNQTLYHLMHLQMNFTWDWVFKF 2047 Query 1004 AQQICEGMAYLHAQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 A ++ G+ LH+ +HRDL + N+L+ ++ +K+ DFGL++ R Sbjct 2048 AIEMVRGVNCLHSWKPVIVHRDLKSLNLLVSDNWTIKVADFGLSRFATAKSASNRTTR-- 2105 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC--DSSQSPPTKFLELIGIAQGQM 1119 + APE D++S G+ L+EL C + P ++F + Q Sbjct 2106 -GTFAYCAPEVF-YGIHTTKGDIFSIGIILWELAVRCIKSKYEKPFSEFKHI------QY 2157 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L + + R P CP +L+ NCWE+ RP+ ++ L + +KY Sbjct 2158 DFQILVQTSKFNLRPTIPQNCPEAFSNLISNCWESSPDNRPSCPEILDSLLDMEKKYTEN 2217 Query 1180 A 1180 Sbjct 2218 K 2218 Score = 193 bits (490), Expect = 2e-48, Method: Composition-based stats. Identities = 64/323 (20%), Positives = 114/323 (35%), Gaps = 57/323 (18%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 T L + +D +EI L+ LG+GT VY R + Sbjct 1933 TKVLMNFNNWAIDGEEIVFLNKLGEGTSAKVYRATWRNQ--------------------- 1971 Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 V +KVL L F + +MS + H+ + +G+ + P+ M+ EY Sbjct 1972 -----EVAVKVLRSEPESQKLLDFLKELEIMSSLRSPHVVYFYGMVLD-PKICMIMEYCS 2025 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAE 749 + L L + + W A ++ ++ L + +VH ++ N+L++ Sbjct 2026 NQTLY-HLMHLQMNFTWDWVFKFAIEMVRGVNCLHSWKPVIVHRDLKSLNLLVS------ 2078 Query 750 GTSPFIKLSDPGVGLGALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + IK++D G+ A ++ + APE G +T D + G L Sbjct 2079 -DNWTIKVADFGLSRFATAKSASNRTTRGTFAYCAPEVFYG---IHTTKGDIFSIGIILW 2134 Query 806 EICFDGEAPLQSRSPSEKEHFYQR------------QHRLPEPSCPQLATLTSQCLTYEP 853 E+ + SE +H + +P+ + L S C P Sbjct 2135 ELAVRCIKSKYEKPFSEFKHIQYDFQILVQTSKFNLRPTIPQNCPEAFSNLISNCWESSP 2194 Query 854 TQRPSFRTILRDLTRLQPHNLAD 876 RPS IL L ++ + Sbjct 2195 DNRPSCPEILDSLLDMEKKYTEN 2217 >sp|Q852Q1|OSK4_ORYSJ Serine/threonine protein kinase OSK4 OS=Oryza sativa subsp. japonica OX=39947 GN=OSK4 PE=1 SV=1 Length=509 Score = 230 bits (586), Expect = 4e-64, Method: Composition-based stats. Identities = 74/280 (26%), Positives = 109/280 (39%), Gaps = 30/280 (11%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQE 947 + R LG G FGKV + + TG VA+K L + K+E Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKRE 65 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006 I ILR H HII+ + + +VMEY G L DY+ + + + QQ Sbjct 66 IKILRLFIHPHIIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQ 123 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I G+ Y H +HRDL N+LLD+ VK+ DFGL+ + +G + ++ SP Sbjct 124 IISGVEYCHRNMVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDG---HFLKTSCGSPN- 179 Query 1067 WYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 + APE + + DVWS GV LY LL + L Sbjct 180 YAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE---------------NIPNLF 224 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + ++ G P L+ + R T + Sbjct 225 KKIKGGI-YTLPSHLSALARDLIPRMLVVDPMKRITIREI 263 Score = 182 bits (461), Expect = 1e-47, Method: Composition-based stats. Identities = 52/332 (16%), Positives = 100/332 (30%), Gaps = 39/332 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 H K LG G+ V ++ G RV + Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKIAEHKLTGH------------------------RVAI 45 Query 642 KVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 K+L+ + ++ ++ H H+ ++ V + +V EY + G L + Sbjct 46 KILNRRQMRNMEMEEKAKREIKILRLFIHPHIIRLYEVIYTPTDIYVVMEYCKFGELFDY 105 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + E+G + + QQ+ S + Y +VH ++ N+LL +KL+ Sbjct 106 I-VEKGRLQEDEARRIFQQIISGVEYCHRNMVVHRDLKPENLLLDSK-------YNVKLA 157 Query 759 DPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 D G+ + + APE + G + +D W G L + Sbjct 158 DFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYALLCGTLPFD 216 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 P+ + + LP L + L +P +R + R I Sbjct 217 DENIPNLFKKIKGGIYTLPSHLSALARDLIPRMLVVDPMKRITIREIREHQWFQIRLPRY 276 Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 + + + + H Sbjct 277 LAVPPPDTAQQAKMIDEDTLQDVVNLGYEKDH 308 >sp|B8BBT7|OSK4_ORYSI Serine/threonine protein kinase OSK4 OS=Oryza sativa subsp. indica OX=39946 GN=OSK4 PE=3 SV=1 Length=509 Score = 230 bits (586), Expect = 4e-64, Method: Composition-based stats. Identities = 74/280 (26%), Positives = 109/280 (39%), Gaps = 30/280 (11%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQE 947 + R LG G FGKV + + TG VA+K L + K+E Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKI----AEHKLTGHRVAIKILNRRQMRNMEMEEKAKRE 65 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006 I ILR H HII+ + + +VMEY G L DY+ + + + QQ Sbjct 66 IKILRLFIHPHIIRLYEVIYTPTD--IYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQ 123 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I G+ Y H +HRDL N+LLD+ VK+ DFGL+ + +G + ++ SP Sbjct 124 IISGVEYCHRNMVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDG---HFLKTSCGSPN- 179 Query 1067 WYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 + APE + + DVWS GV LY LL + L Sbjct 180 YAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE---------------NIPNLF 224 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + ++ G P L+ + R T + Sbjct 225 KKIKGGI-YTLPSHLSALARDLIPRMLVVDPMKRITIREI 263 Score = 182 bits (461), Expect = 1e-47, Method: Composition-based stats. Identities = 52/332 (16%), Positives = 100/332 (30%), Gaps = 39/332 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 H K LG G+ V ++ G RV + Sbjct 10 HSEALKNYNLGRTLGIGSFGKVKIAEHKLTGH------------------------RVAI 45 Query 642 KVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 K+L+ + ++ ++ H H+ ++ V + +V EY + G L + Sbjct 46 KILNRRQMRNMEMEEKAKREIKILRLFIHPHIIRLYEVIYTPTDIYVVMEYCKFGELFDY 105 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + E+G + + QQ+ S + Y +VH ++ N+LL +KL+ Sbjct 106 I-VEKGRLQEDEARRIFQQIISGVEYCHRNMVVHRDLKPENLLLDSK-------YNVKLA 157 Query 759 DPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 D G+ + + APE + G + +D W G L + Sbjct 158 DFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYALLCGTLPFD 216 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 P+ + + LP L + L +P +R + R I Sbjct 217 DENIPNLFKKIKGGIYTLPSHLSALARDLIPRMLVVDPMKRITIREIREHQWFQIRLPRY 276 Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 + + + + H Sbjct 277 LAVPPPDTAQQAKMIDEDTLQDVVNLGYEKDH 308 >sp|Q9FIJ6|ACCR4_ARATH Serine/threonine-protein kinase-like protein CCR4 OS=Arabidopsis thaliana OX=3702 GN=CCR4 PE=1 SV=1 Length=751 Score = 236 bits (602), Expect = 4e-64, Method: Composition-based stats. Identities = 85/396 (21%), Positives = 145/396 (37%), Gaps = 42/396 (11%) Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTS-----------QCLTYEPTQRPS 858 DGE P S+ + + +R C +L +C ++ + Sbjct 344 DGEFPDTRAQNSKNKTWSRRNIAFLVVGCVGTFSLLLVISFLIFKSHCRCRVHDSGRLDD 403 Query 859 FRTILRDL-TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917 RTI + + + D LG G FG V Sbjct 404 TRTIDIPKLEKRLCTLASLGNPGQLMEFSIDELALATDGFSVRFHLGIGSFGSVYQGVL- 462 Query 918 PTNDGTGEMVAVKA------------LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGC 965 G VA+K ++ + S + E++ + L H+++++ G Sbjct 463 ----SDGRHVAIKRAELTNPTLSGTTMRHRRADKD-SAFVNELESMSRLNHKNLVRLLGF 517 Query 966 CEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHA---QHY 1019 ED E+ LV EY+ GSL D+L + L+ A G+ YLH Sbjct 518 YEDTEER--ILVYEYMKNGSLADHLHNPQFDPLSWQTRLMIALDAARGIQYLHEFIVPPV 575 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ + N+LLD K+ DFGL++ P E + + + + PE K + Sbjct 576 IHRDIKSSNILLDATWTAKVSDFGLSQMGPTEEDDVSHLSLHAAGTLGYIDPEYYKFQQL 635 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 SDV+SFGV L ELL+ + + L+ + + +L++ P P Sbjct 636 TTKSDVYSFGVVLLELLSGHKAIHNNEDENPRNLVEYVVPYILLDEAHRILDQRIPPPTP 695 Query 1138 --DKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + V +L C + RP+ ++ L++ Sbjct 696 YEIEAVAHVGYLAAECLMPCSRKRPSMVEVVSKLES 731 Score = 204 bits (518), Expect = 3e-53, Method: Composition-based stats. Identities = 64/339 (19%), Positives = 116/339 (34%), Gaps = 54/339 (16%) Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P L + + +P L + + + HLG G+ +VY+G L Sbjct 410 PKLEKRLCTL-ASLGNPGQLMEFSIDELALATDGFSVRFHLGIGSFGSVYQGVLSDGRHV 468 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 + ++ + + D AF MS+++H +L + Sbjct 469 AIKRAELTNPTLSGT-------------TMRHRRADKDSAFVNELESMSRLNHKNLVRLL 515 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLEN---KNL 730 G E I+V EY+++G L L + + ++++A A + YL + Sbjct 516 GFYEDTEERILVYEYMKNGSLADHLHNPQFDPLSWQTRLMIALDAARGIQYLHEFIVPPV 575 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV--------ERIPWLAPE 782 +H ++ NILL + K+SD G+ + E+ V + ++ PE Sbjct 576 IHRDIKSSNILLD-------ATWTAKVSDFGLSQMGPTEEDDVSHLSLHAAGTLGYIDPE 628 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFD--------GEAPLQSRSPSEKEHFYQRQHRLP 834 L+T D + FG LLE+ E P HR+ Sbjct 629 YYK--FQQLTTKSDVYSFGVVLLELLSGHKAIHNNEDENPRNLVEYVVPYILLDEAHRIL 686 Query 835 EPSCP-----------QLATLTSQCLTYEPTQRPSFRTI 862 + P + L ++CL +RPS + Sbjct 687 DQRIPPPTPYEIEAVAHVGYLAAECLMPCSRKRPSMVEV 725 >sp|Q9LZM4|WAKLQ_ARATH Wall-associated receptor kinase-like 20 OS=Arabidopsis thaliana OX=3702 GN=WAKL20 PE=2 SV=1 Length=657 Score = 234 bits (596), Expect = 4e-64, Method: Composition-based stats. Identities = 67/286 (23%), Positives = 123/286 (43%), Gaps = 24/286 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG+V + G + A+K K + + E+ IL + H +++ Sbjct 369 IGTGGFGEVFKAVLE-----DGTITAIKRAKLN-NTKGTDQILNEVRILCQVNHRSLVRL 422 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR------HSIGLAQLLLFAQQICEGMAYLHA 1016 GCC D + L+ E++P G+L ++L + + L A Q EG+AYLH+ Sbjct 423 LGCCVDL--ELPLLIYEFIPNGTLFEHLHGSSDRTWKPLTWRRRLQIAYQTAEGLAYLHS 480 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR---VREDGDSPVFWYAP 1070 HRD+ + N+LLD K+ DFGL++ V + + + P Sbjct 481 AAQPPIYHRDVKSSNILLDEKLNAKVSDFGLSRLVDLTETANNESHIFTGAQGTLGYLDP 540 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E + ++ SDV+SFGV L E++T + + + + L+ M RLTE ++ Sbjct 541 EYYRNFQLTDKSDVYSFGVVLLEMVTSKKAIDFTREEEDVNLVMYINKMMDQERLTECID 600 Query 1130 RGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + + ++ +L C RP+ + + ++ + Sbjct 601 PLLKKTANKIDMQTIQQLGNLASACLNERRQNRPSMKEVADEIEYI 646 Score = 209 bits (533), Expect = 8e-56, Method: Composition-based stats. Identities = 63/351 (18%), Positives = 111/351 (32%), Gaps = 74/351 (21%) Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615 E ++ S R +++ ++ + +G G V++ L Sbjct 333 KEREEMLSANSTGKSSRIFTGREITK---ATNNFSKDNLIGTGGFGEVFKAVLEDGTIT- 388 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675 +K ++ ++ QV+H L + G Sbjct 389 ------------------------AIKRAKLNNTKGTDQILNEVRILCQVNHRSLVRLLG 424 Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRERGHV--PMAW--KMVVAQQLASALSYLEN---K 728 CV +++ E++ +G L L P+ W ++ +A Q A L+YL + Sbjct 425 CCVDLELPLLIYEFIPNGTLFEHLHGSSDRTWKPLTWRRRLQIAYQTAEGLAYLHSAAQP 484 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV----------ERIPW 778 + H +V NILL K+SD G+ E + + Sbjct 485 PIYHRDVKSSNILLDEKL-------NAKVSDFGLSRLVDLTETANNESHIFTGAQGTLGY 537 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-----EHFYQRQHRL 833 L PE L+ D + FG LLE+ +A +R + + Q RL Sbjct 538 LDPEYYRN--FQLTDKSDVYSFGVVLLEMVTSKKAIDFTREEEDVNLVMYINKMMDQERL 595 Query 834 PEPSCPQLAT---------------LTSQCLTYEPTQRPSFRTILRDLTRL 869 E P L L S CL RPS + + ++ + Sbjct 596 TECIDPLLKKTANKIDMQTIQQLGNLASACLNERRQNRPSMKEVADEIEYI 646 >sp|Q54QQ1|PHG2_DICDI Serine/threonine-protein kinase phg2 OS=Dictyostelium discoideum OX=44689 GN=phg2 PE=1 SV=1 Length=1387 Score = 242 bits (618), Expect = 5e-64, Method: Composition-based stats. Identities = 69/289 (24%), Positives = 124/289 (43%), Gaps = 20/289 (7%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHE 957 I+ +G G + KV Y + VA+K ++ ++ + +K+E DIL T+ Sbjct 809 YIKRIGSGTYSKVYKGKYR------DKFVAIKTMRGSNMTTEQIESFKKECDILSTIQSP 862 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLH 1015 +I + G C + E L +V+EY G+L L + + ++ EG+ YLH Sbjct 863 LLISFYGSCIE--ESQLSMVVEYCSKGTLHKVLNNPLLDFDWDKWFKWMTEVVEGVRYLH 920 Query 1016 AQH--YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + + +HRDL N+L+ +D K+ DFGL + + + + + APE Sbjct 921 SMNPPMVHRDLKTLNILISSDWTAKLCDFGLTRTMTMTN--VSTLGMLRGTMAYTAPEIY 978 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 F SDV+S GV ++E + C S +L M + + + R Sbjct 979 DGLLFNTKSDVYSLGVIMWEAIQRCISGV-----YLRPFHEHPISMDIQIIILTSKNKVR 1033 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182 + CP ++ L+ CW+ RP + ++ IL T+ + + Sbjct 1034 PKISENCPEQLKTLITRCWDENPDKRPNCDEILEILLTMKQAHDENKDE 1082 Score = 183 bits (464), Expect = 2e-45, Method: Composition-based stats. Identities = 59/315 (19%), Positives = 108/315 (34%), Gaps = 55/315 (17%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 H + ++ + +G GT + VY+G+ R + V + Sbjct 800 HWIPSADLEYIKRIGSGTYSKVYKGKYRDKF--------------------------VAI 833 Query 642 KVLDPSHH--DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 K + S+ + +F + ++S + L +G C+ + MV EY G L L Sbjct 834 KTMRGSNMTTEQIESFKKECDILSTIQSPLLISFYGSCIEESQLSMVVEYCSKGTLHKVL 893 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKL 757 ++ + YL + N +VH ++ NIL++ + KL Sbjct 894 NNPLLDFDWDKWFKWMTEVVEGVRYLHSMNPPMVHRDLKTLNILIS-------SDWTAKL 946 Query 758 SDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI---CF 809 D G+ + + APE G +T D + G + E C Sbjct 947 CDFGLTRTMTMTNVSTLGMLRGTMAYTAPEIYDGLL--FNTKSDVYSLGVIMWEAIQRCI 1004 Query 810 DG--EAPLQSRSPSEKEHF------YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861 G P S + + ++ E QL TL ++C P +RP+ Sbjct 1005 SGVYLRPFHEHPISMDIQIIILTSKNKVRPKISENCPEQLKTLITRCWDENPDKRPNCDE 1064 Query 862 ILRDLTRLQPHNLAD 876 IL L ++ + + Sbjct 1065 ILEILLTMKQAHDEN 1079 >sp|Q9ZWC8|BRL1_ARATH Serine/threonine-protein kinase BRI1-like 1 OS=Arabidopsis thaliana OX=3702 GN=BRL1 PE=1 SV=1 Length=1166 Score = 241 bits (616), Expect = 5e-64, Method: Composition-based stats. Identities = 76/296 (26%), Positives = 124/296 (42%), Gaps = 22/296 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG+V G +VA+K L G R + E++ + + H +++ Sbjct 865 VGSGGFGEVYKAQLR-----DGSVVAIKKLIRITGQGDRE-FMAEMETIGKIKHRNLVPL 918 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-------IGLAQLLLFAQQICEGMAYLH 1015 G C+ E+ LV EY+ GSL L S + A A G+A+LH Sbjct 919 LGYCKVGEER--LLVYEYMKWGSLETVLHEKSSKKGGIYLNWAARKKIAIGAARGLAFLH 976 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 H IHRD+ + NVLLD D ++ DFG+A+ V + V +P + PE Sbjct 977 HSCIPHIIHRDMKSSNVLLDEDFEARVSDFGMARLVSALDTHLSVSTLAGTP-GYVPPEY 1035 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLRLTELLERG 1131 + ++ DV+S+GV L ELL+ + L+G A+ R E+L+ Sbjct 1036 YQSFRCTAKGDVYSYGVILLELLSGKKPIDPGEFGEDNNLVGWAKQLYREKRGAEILDPE 1095 Query 1132 ERLPRP-DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH-EKYQGQAPSVFS 1185 + D + C + RPT L+ + K + + + ++ FS Sbjct 1096 LVTDKSGDVELFHYLKIASQCLDDRPFKRPTMIQLMAMFKEMKADTEEDESLDEFS 1151 Score = 211 bits (536), Expect = 3e-54, Method: Composition-based stats. Identities = 60/329 (18%), Positives = 113/329 (34%), Gaps = 68/329 (21%) Query 576 LSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L +L+F + + + +G G VY+ +LR Sbjct 844 LRKLTFAHLLEATNGFSAETMVGSGGFGEVYKAQLRDGS--------------------- 882 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 V +K L F + ++ H +L + G C G E ++V EY++ G Sbjct 883 ----VVAIKKLIRITGQGDREFMAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKWG 938 Query 694 PLDVWLRRERGH-----VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745 L+ L + + A + +A A L++L + +++H ++ N+LL Sbjct 939 SLETVLHEKSSKKGGIYLNWAARKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDED 998 Query 746 GLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWG 799 A ++SD G+ LS ++ PE + + D + Sbjct 999 FEA-------RVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQ--SFRCTAKGDVYS 1049 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQ-----RQHRLPEPSCPQLAT----------- 843 +G LLE+ + + R+ R E P+L T Sbjct 1050 YGVILLELLSGKKPIDPGEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELFHY 1109 Query 844 --LTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + SQCL P +RP+ ++ ++ Sbjct 1110 LKIASQCLDDRPFKRPTMIQLMAMFKEMK 1138 >sp|Q38997|KIN10_ARATH SNF1-related protein kinase catalytic subunit alpha KIN10 OS=Arabidopsis thaliana OX=3702 GN=KIN10 PE=1 SV=3 Length=512 Score = 230 bits (586), Expect = 5e-64, Method: Composition-based stats. Identities = 76/268 (28%), Positives = 111/268 (41%), Gaps = 30/268 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEHI 959 LG G FG+V + + TG VA+K L + + ++EI ILR H HI Sbjct 24 TLGIGSFGRVKI----AEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPHI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I+ E + + LVMEYV G L DY+ + + + F QQI G+ Y H Sbjct 80 IRLYEVIETPTD--IYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNM 137 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRDL N+LLD+ VKI DFGL+ + +G + ++ SP + APE + + Sbjct 138 VVHRDLKPENLLLDSKCNVKIADFGLSNIMRDG---HFLKTSCGSPN-YAAPEVISGKLY 193 Query 1079 -YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 DVWS GV LY LL + L + ++ G P Sbjct 194 AGPEVDVWSCGVILYALLCGTLPFDDE---------------NIPNLFKKIKGGI-YTLP 237 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165 L+ + R T + Sbjct 238 SHLSPGARDLIPRMLVVDPMKRVTIPEI 265 Score = 184 bits (467), Expect = 3e-48, Method: Composition-based stats. Identities = 49/326 (15%), Positives = 95/326 (29%), Gaps = 39/326 (12%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP- 646 LG G+ V + G +V +K+L+ Sbjct 18 NYKLGRTLGIGSFGRVKIAEHALTGH------------------------KVAIKILNRR 53 Query 647 --SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + ++ ++ H H+ ++ V + +V EYV G L ++ E+G Sbjct 54 KIKNMEMEEKVRREIKILRLFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYI-VEKG 112 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763 + QQ+ S + Y +VH ++ N+LL +K++D G+ Sbjct 113 RLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSKC-------NVKIADFGLSN 165 Query 764 --LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + + APE + G + +D W G L + P+ Sbjct 166 IMRDGHFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYALLCGTLPFDDENIPN 224 Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 + + LP P L + L +P +R + I + + Sbjct 225 LFKKIKGGIYTLPSHLSPGARDLIPRMLVVDPMKRVTIPEIRQHPWFQAHLPRYLAVPPP 284 Query 882 PDSPASDPTVFHKRYLKKIRDLGEGH 907 + H Sbjct 285 DTVQQAKKIDEEILQEVINMGFDRNH 310 >sp|P24941|CDK2_HUMAN Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2 Length=298 Score = 223 bits (567), Expect = 5e-64, Method: Composition-based stats. Identities = 68/289 (24%), Positives = 122/289 (42%), Gaps = 30/289 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ Sbjct 1 MENFQKVEKIGEGTYGVV----YKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICE 1009 L H +I+K E L LV E++ L+ ++ I L + + Q+ + Sbjct 57 ELNHPNIVKLLDVI--HTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQ 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 G+A+ H+ +HRDL +N+L++ + +K+ DFGLA+A R +++ A Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVP---VRTYTHEVVTLWYRA 170 Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL- 1127 PE L K+Y A D+WS G E++T ++ +L I + T + Sbjct 171 PEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPG-DSEIDQLFRIFRTLGTPDEVVWPG 229 Query 1128 --LERGERLPRPDKCPCEV-----------YHLMKNCWETEASFRPTFE 1163 + P + L+ + + R + + Sbjct 230 VTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAK 278 Score = 171 bits (433), Expect = 5e-46, Method: Composition-based stats. Identities = 48/266 (18%), Positives = 95/266 (36%), Gaps = 40/266 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 + ++ +G+GT VY+ R ++ G V LK Sbjct 1 MENFQKVEKIGEGTYGVVYKARNKLTGE------------------------VVALKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 LD + SL+ +++H ++ + V + +V E++ H L ++ Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-HQDLKKFMDASA 95 Query 704 -GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 +P+ QL L++ + ++H ++ +N+L+ G IKL+D G+ Sbjct 96 LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGA-------IKLADFGL 148 Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + + APE L G STA+D W G E+ Sbjct 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKY-YSTAVDIWSLGCIFAEMVTRRALFPGDS 207 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ E P + ++ Sbjct 208 EIDQLFRIFRTLGTPDEVVWPGVTSM 233 >sp|A3B529|CIPKS_ORYSJ CBL-interacting protein kinase 28 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK28 PE=2 SV=2 Length=435 Score = 227 bits (579), Expect = 5e-64, Method: Composition-based stats. Identities = 60/266 (23%), Positives = 109/266 (41%), Gaps = 26/266 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960 LG+G FGKV N +G+ VA+K + + + K+EI I+R + H +++ Sbjct 17 LGQGTFGKVYY----ARNLSSGQSVAIKMIDKEKILKVGLMEQIKREISIMRLVRHPNVL 72 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + + ++ +EY G L + R + + QQ+ M Y H++ Sbjct 73 QLFEVMATKS--NIYFALEYAKGGELFHKMARAKLNEESARNYFQQLISAMDYCHSRGVY 130 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 HRDL N+LLD + +K+ DFGL+ + + +P + APE L + Sbjct 131 HRDLKPENLLLDENETLKVSDFGLSALAESRRQDGLLHTACGTPA-YVAPEVLSRKGYSG 189 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +DVWS GV L+ L+ + + + ++ + R P Sbjct 190 SKADVWSCGVILFVLVANYLPFHD--------------RNIIQMYRKIAKAEYR--CPRH 233 Query 1140 CPCEVYHLMKNCWETEASFRPTFENL 1165 E+ L+ + + S R + + Sbjct 234 FSAELKELLYGILDPDPSTRMSISRI 259 Score = 189 bits (480), Expect = 8e-51, Method: Composition-based stats. Identities = 59/299 (20%), Positives = 95/299 (32%), Gaps = 43/299 (14%) Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 + V + LGQGT VY R G Sbjct 1 MEERSVLMERYVIGRQLGQGTFGKVYYARNLSSGQS------------------------ 36 Query 639 VVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K++D + S+M V H ++ + V EY + G L Sbjct 37 VAIKMIDKEKILKVGLMEQIKREISIMRLVRHPNVLQLFEVMATKSNIYFALEYAKGGEL 96 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 + + R + QQL SA+ Y ++ + H ++ N+LL + + Sbjct 97 --FHKMARAKLNEESARNYFQQLISAMDYCHSRGVYHRDLKPENLLLDE-------NETL 147 Query 756 KLSDPGVGLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 K+SD G+ A SR ++APE L S + D W G L + Sbjct 148 KVSDFGLSALAESRRQDGLLHTACGTPAYVAPEVLSRKGYS-GSKADVWSCGVILFVLVA 206 Query 810 DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + + ++R P +L L L +P+ R S I R Sbjct 207 NYLPFHDRNIIQMYRKIAKAEYRCPRHFSAELKELLYGILDPDPSTRMSISRIKRSAWY 265 >sp|Q9SAJ2|RAF20_ARATH RAF-like serine/threonine-protein kinase 20 OS=Arabidopsis thaliana OX=3702 GN=RAF20 PE=1 SV=1 Length=1248 Score = 241 bits (616), Expect = 5e-64, Method: Composition-based stats. Identities = 79/299 (26%), Positives = 125/299 (42%), Gaps = 41/299 (14%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-----GPQHRS--GWKQEIDILRTL 954 +LG G FG V + ++ VA+K +K C Q R + E +IL L Sbjct 969 ELGSGTFGTVYHGKWRGSD------VAIKRIKKSCFAGRSSEQERLTGEFWGEAEILSKL 1022 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMA 1012 +H +++ + G +D +L V EY+ GSLR L R + + L+ A GM Sbjct 1023 HHPNVVAFYGVVKDGPGGTLATVTEYMVDGSLRHVLVRKDRHLDRRKRLIIAMDAAFGME 1082 Query 1013 YLHAQHYIHRDLAARNVLLD----NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 YLH+++ +H DL N+L++ + + K+GDFGL+K V + W Sbjct 1083 YLHSKNTVHFDLKCDNLLVNLKDPSRPICKVGDFGLSKI----KRNTLVSGGVRGTLPWM 1138 Query 1069 APECLKE--YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 APE L K DV+SFG+ L+E+LT + + + + Sbjct 1139 APELLNGSSSKVSEKVDVFSFGIVLWEILTGEEPYANMHYGAI--------------IGG 1184 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG--QAPSV 1183 ++ R P C E LM+ CW RP+F + L+ + PS Sbjct 1185 IVNNTLRPTIPGFCDDEWRTLMEECWAPNPMARPSFTEIAGRLRVMSSAATSTQSKPSA 1243 Score = 239 bits (611), Expect = 2e-63, Method: Composition-based stats. Identities = 83/382 (22%), Positives = 138/382 (36%), Gaps = 46/382 (12%) Query 504 KFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLII 563 + + Q G E G S+ Q + + + + P Sbjct 879 QLTLGQDYGGNFSEKDGGGTGSIPPALENEQMKVTESEEFGAMVENLRTPDSEPKDEKTE 938 Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 R A P + +++ +L LG GT VY G+ R Sbjct 939 TRHAALPPLGSEFDYSGLQIIKNEDLEELRELGSGTFGTVYHGKWRGSD----------- 987 Query 624 EDPLVPGRDRGQELRVVLKVLDPS--------HHDIALAFYETASLMSQVSHTHLAFVHG 675 V +K + S + F+ A ++S++ H ++ +G Sbjct 988 ---------------VAIKRIKKSCFAGRSSEQERLTGEFWGEAEILSKLHHPNVVAFYG 1032 Query 676 VCVRGPENIM--VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHG 733 V GP + VTEY+ G L L R+ H+ ++++A A + YL +KN VH Sbjct 1033 VVKDGPGGTLATVTEYMVDGSLRHVLVRKDRHLDRRKRLIIAMDAAFGMEYLHSKNTVHF 1092 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANS 790 ++ N+L+ L + + P K+ D G+ L +PW+APE L G ++ Sbjct 1093 DLKCDNLLV---NLKDPSRPICKVGDFGLSKIKRNTLVSGGVRGTLPWMAPELLNGSSSK 1149 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQ 847 +S +D + FG L EI GE P + + +P + TL + Sbjct 1150 VSEKVDVFSFGIVLWEIL-TGEEPYANMHYGAIIGGIVNNTLRPTIPGFCDDEWRTLMEE 1208 Query 848 CLTYEPTQRPSFRTILRDLTRL 869 C P RPSF I L + Sbjct 1209 CWAPNPMARPSFTEIAGRLRVM 1230 >sp|Q63699|CDK2_RAT Cyclin-dependent kinase 2 OS=Rattus norvegicus OX=10116 GN=Cdk2 PE=1 SV=1 Length=298 Score = 223 bits (567), Expect = 6e-64, Method: Composition-based stats. Identities = 67/289 (23%), Positives = 122/289 (42%), Gaps = 30/289 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ Sbjct 1 MENFQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICE 1009 L H +I+K E L LV E++ L+ ++ + L + + Q+ + Sbjct 57 ELNHPNIVKLLDVI--HTENKLYLVFEFLHQ-DLKKFMDASALTGLPLPLIKSYLFQLLQ 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 G+A+ H+ +HRDL +N+L++ + +K+ DFGLA+A R +++ A Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVP---VRTYTHEVVTLWYRA 170 Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL- 1127 PE L K+Y A D+WS G E++T ++ +L I + T + Sbjct 171 PEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPG-DSEIDQLFRIFRTLGTPDEVVWPG 229 Query 1128 --LERGERLPRPDKCPCEV-----------YHLMKNCWETEASFRPTFE 1163 + P + L+ + + R + + Sbjct 230 VTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAK 278 Score = 171 bits (432), Expect = 6e-46, Method: Composition-based stats. Identities = 47/266 (18%), Positives = 95/266 (36%), Gaps = 40/266 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 + ++ +G+GT VY+ + ++ G V LK Sbjct 1 MENFQKVEKIGEGTYGVVYKAKNKLTGE------------------------VVALKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 LD + SL+ +++H ++ + V + +V E++ H L ++ Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-HQDLKKFMDASA 95 Query 704 -GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 +P+ QL L++ + ++H ++ +N+L+ G IKL+D G+ Sbjct 96 LTGLPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEG-------SIKLADFGL 148 Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + + APE L G STA+D W G E+ Sbjct 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKY-YSTAVDIWSLGCIFAEMVTRRALFPGDS 207 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ E P + ++ Sbjct 208 EIDQLFRIFRTLGTPDEVVWPGVTSM 233 >sp|C0LGG4|Y1518_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g51860 OS=Arabidopsis thaliana OX=3702 GN=At1g51860 PE=2 SV=2 Length=890 Score = 238 bits (607), Expect = 6e-64, Method: Composition-based stats. Identities = 68/284 (24%), Positives = 118/284 (42%), Gaps = 18/284 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R LG+G FG V D G VAVK L Q +K E+++L + Sbjct 582 MTNNFERVLGKGGFGTVYHGNLD------GAEVAVKMLSH-SSAQGYKEFKAEVELLLRV 634 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEG 1010 +H H++ G C+D +L L+ EY+ G LR+ + + + A + +G Sbjct 635 HHRHLVGLVGYCDDGD--NLALIYEYMANGDLRENMSGKRGGNVLTWENRMQIAVEAAQG 692 Query 1011 MAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH +HRD+ N+LL+ K+ DFGL+++ P E + +P + Sbjct 693 LEYLHNGCRPPMVHRDVKTTNILLNERCGAKLADFGLSRSFPIDGECHVSTVVAGTP-GY 751 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 PE + SDV+SFGV L E++T+ + + +T + + Sbjct 752 LDPEYYRTNWLSEKSDVYSFGVVLLEIVTNQPVIDKTRER-PHINDWVGFMLTKGDIKSI 810 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 ++ ++ L C ++ RPT +++ L Sbjct 811 VDPKLMGDYDTNGAWKIVELALACVNPSSNRRPTMAHVVMELND 854 Score = 209 bits (531), Expect = 3e-54, Method: Composition-based stats. Identities = 73/344 (21%), Positives = 119/344 (35%), Gaps = 62/344 (18%) Query 553 PQPGETSNLIIMRGARASPRTLNL-SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 P P T ++ ++P + ++++ V + LG+G VY G L Sbjct 547 PPPLVTPGIVKSETRSSNPSIITRERKITYPEVLKMTNNFERVLGKGGFGTVYHGNL--- 603 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 V +K+L S F L+ +V H HL Sbjct 604 -----------------------DGAEVAVKMLSHSSAQGYKEFKAEVELLLRVHHRHLV 640 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN-- 727 + G C G ++ EY+ +G L + +RG + W +M +A + A L YL N Sbjct 641 GLVGYCDDGDNLALIYEYMANGDLRENMSGKRGGNVLTWENRMQIAVEAAQGLEYLHNGC 700 Query 728 -KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR------EERVERIPWLA 780 +VH +V NILL A KL+D G+ +L Sbjct 701 RPPMVHRDVKTTNILLNERCGA-------KLADFGLSRSFPIDGECHVSTVVAGTPGYLD 753 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR---SPSEKEHFYQRQHRLPEPS 837 PE N LS D + FG LLEI + ++R ++ F + + Sbjct 754 PEYYRT--NWLSEKSDVYSFGVVLLEIVTNQPVIDKTRERPHINDWVGFMLTKGDIKSIV 811 Query 838 CPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRL 869 P+L L C+ +RP+ ++ +L Sbjct 812 DPKLMGDYDTNGAWKIVELALACVNPSSNRRPTMAHVVMELNDC 855 >sp|Q8VZJ9|CRCK2_ARATH Calmodulin-binding receptor-like cytoplasmic kinase 2 OS=Arabidopsis thaliana OX=3702 GN=CRCK2 PE=2 SV=1 Length=411 Score = 226 bits (577), Expect = 6e-64, Method: Composition-based stats. Identities = 80/319 (25%), Positives = 121/319 (38%), Gaps = 19/319 (6%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + + D + +G+G FG V G+ AVK Sbjct 93 QRSYGNANETEHTRFTFDEIYDATKNFSPSFRIGQGGFGTVYKVKLR-----DGKTFAVK 147 Query 931 ALKA---DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 K D + + EI L + H ++KY G EK LV+EYV G+LR Sbjct 148 RAKKSMHDDRQGADAEFMSEIQTLAQVTHLSLVKYYGFVVHNDEK--ILVVEYVANGTLR 205 Query 988 DYL---PRHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGD 1041 D+L ++ +A L A + + YLH IHRD+ + N+LL + K+ D Sbjct 206 DHLDCKEGKTLDMATRLDIATDVAHAITYLHMYTQPPIIHRDIKSSNILLTENYRAKVAD 265 Query 1042 FGLAKAVPEGHE-YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100 FG A+ P+ V + PE L Y+ SDV+SFGV L ELLT Sbjct 266 FGFARLAPDTDSGATHVSTQVKGTAGYLDPEYLTTYQLTEKSDVYSFGVLLVELLTGRRP 325 Query 1101 SQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK-CPCEVYHLMKNCWETEASF 1158 + S K I A + T +L+ + +V + C Sbjct 326 IELSRGQKERITIRWAIKKFTSGDTISVLDPKLEQNSANNLALEKVLEMAFQCLAPHRRS 385 Query 1159 RPTFENLIPILKTVHEKYQ 1177 RP+ + IL + + Y+ Sbjct 386 RPSMKKCSEILWGIRKDYR 404 Score = 197 bits (500), Expect = 1e-53, Method: Composition-based stats. Identities = 63/343 (18%), Positives = 113/343 (33%), Gaps = 62/343 (18%) Query 564 MRGARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 ++ + + ++ +F + K + +GQG VY+ +LR + + Sbjct 92 VQRSYGNANETEHTRFTFDEIYDATKNFSPSFRIGQGGFGTVYKVKLRDGKTFAVKR--- 148 Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 K + F ++QV+H L +G V Sbjct 149 ------------------AKKSMHDDRQGADAEFMSEIQTLAQVTHLSLVKYYGFVVHND 190 Query 682 ENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCG 737 E I+V EYV +G L L + G + MA ++ +A +A A++YL ++H ++ Sbjct 191 EKILVVEYVANGTLRDHLDCKEGKTLDMATRLDIATDVAHAITYLHMYTQPPIIHRDIKS 250 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREE--------RVERIPWLAPECLPGGAN 789 NILL + K++D G A + +L PE L Sbjct 251 SNILLTE-------NYRAKVADFGFARLAPDTDSGATHVSTQVKGTAGYLDPEYLTT--Y 301 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC----------- 838 L+ D + FG L+E+ SR E+ + Sbjct 302 QLTEKSDVYSFGVLLVELLTGRRPIELSRGQKERITIRWAIKKFTSGDTISVLDPKLEQN 361 Query 839 -------PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 ++ + QCL RPS + L ++ Sbjct 362 SANNLALEKVLEMAFQCLAPHRRSRPSMKKCSEILWGIRKDYR 404 >sp|Q8GYF5|WAKLR_ARATH Wall-associated receptor kinase-like 21 OS=Arabidopsis thaliana OX=3702 GN=WAKL21 PE=2 SV=2 Length=622 Score = 233 bits (593), Expect = 6e-64, Method: Composition-based stats. Identities = 69/314 (22%), Positives = 126/314 (40%), Gaps = 20/314 (6%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 LG G +G V + ++ VA+K LK Sbjct 300 PFYTYKEIEKATDSFSDKNMLGTGAYGTVYAGEFPNSS-----CVAIKRLKHKDTT-SID 353 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----SIGLA 998 EI +L ++ H ++++ GCC GE LV E++P G+L +L + Sbjct 354 QVVNEIKLLSSVSHPNLVRLLGCCFADGEP--FLVYEFMPNGTLYQHLQHERGQPPLSWQ 411 Query 999 QLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKA-VPEGHEY 1054 L A Q +A+LH+ HRD+ + N+LLD++ KI DFGL++ + E Sbjct 412 LRLAIACQTANAIAHLHSSVNPPIYHRDIKSSNILLDHEFNSKISDFGLSRLGMSTDFEA 471 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIG 1113 + + P+ ++++ SDV+SFGV L E+++ + P + L Sbjct 472 SHISTAPQGTPGYLDPQYHQDFQLSDKSDVYSFGVVLVEIISGFKVIDFTRPYSEVNLAS 531 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170 +A ++ R+ ++++ K +++L + C + RPT + L Sbjct 532 LAVDRIGRGRVVDIIDPCLNKEINPKMFASIHNLAELAFRCLSFHRNMRPTMVEITEDLH 591 Query 1171 TVHEKYQGQAPSVF 1184 + + G F Sbjct 592 RIKLMHYGTESGKF 605 Score = 210 bits (535), Expect = 2e-56, Method: Composition-based stats. Identities = 69/380 (18%), Positives = 122/380 (32%), Gaps = 60/380 (16%) Query 544 CFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRT 601 F ++ + +N ++ A S ++ ++ + + LG G Sbjct 271 FFRNKQSASSERASIANRLLCELAGNSSVPF----YTYKEIEKATDSFSDKNMLGTGAYG 326 Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL 661 VY G + V +K L L Sbjct 327 TVYAG-------------------------EFPNSSCVAIKRLKHKDTTSIDQVVNEIKL 361 Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLA 719 +S VSH +L + G C E +V E++ +G L L+ ERG P++W ++ +A Q A Sbjct 362 LSSVSHPNLVRLLGCCFADGEPFLVYEFMPNGTLYQHLQHERGQPPLSWQLRLAIACQTA 421 Query 720 SALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV--- 773 +A+++L + + H ++ NILL + K+SD G+ +S + Sbjct 422 NAIAHLHSSVNPPIYHRDIKSSNILLDHEFNS-------KISDFGLSRLGMSTDFEASHI 474 Query 774 -----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 +L P+ LS D + FG L+EI + +R SE Sbjct 475 STAPQGTPGYLDPQY--HQDFQLSDKSDVYSFGVVLVEIISGFKVIDFTRPYSEVNLASL 532 Query 829 RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASD 888 R+ ++ + CL E + + N + Sbjct 533 AVDRIGRG---RVVDIIDPCLNKEINPKMFASI----HNLAELAFRCLSFHRNMRPTMVE 585 Query 889 PTVFHKRYLKKIRDLGEGHF 908 T R G F Sbjct 586 ITEDLHRIKLMHYGTESGKF 605 >sp|O55076|CDK2_CRIGR Cyclin-dependent kinase 2 OS=Cricetulus griseus OX=10029 GN=CDK2 PE=1 SV=1 Length=298 Score = 222 bits (566), Expect = 6e-64, Method: Composition-based stats. Identities = 68/289 (24%), Positives = 122/289 (42%), Gaps = 30/289 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ Sbjct 1 MENFQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICE 1009 L H +I+K E L LV E++ L+ ++ I L + + Q+ + Sbjct 57 ELNHPNIVKLLDVI--HTENKLYLVFEFLHQ-DLKKFMDASAVTGIPLPLIKSYLFQLLQ 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 G+A+ H+ +HRDL +N+L++ + +K+ DFGLA+A R +++ A Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVP---VRTYTHEVVTLWYRA 170 Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL- 1127 PE L K+Y A D+WS G E++T ++ +L I + T + Sbjct 171 PEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPG-DSEIDQLFRIFRTLGTPDEVVWPG 229 Query 1128 --LERGERLPRPDKCPCEV-----------YHLMKNCWETEASFRPTFE 1163 + P + L+ + + R + + Sbjct 230 VTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAK 278 Score = 171 bits (432), Expect = 7e-46, Method: Composition-based stats. Identities = 47/266 (18%), Positives = 95/266 (36%), Gaps = 40/266 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 + ++ +G+GT VY+ + ++ G V LK Sbjct 1 MENFQKVEKIGEGTYGVVYKAKNKLTGE------------------------VVALKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 LD + SL+ +++H ++ + V + +V E++ H L ++ Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-HQDLKKFMDASA 95 Query 704 -GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 +P+ QL L++ + ++H ++ +N+L+ G IKL+D G+ Sbjct 96 VTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEG-------SIKLADFGL 148 Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + + APE L G STA+D W G E+ Sbjct 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKY-YSTAVDIWSLGCIFAEMVTRRALFPGDS 207 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ E P + ++ Sbjct 208 EIDQLFRIFRTLGTPDEVVWPGVTSM 233 >sp|Q9LWM4|CIPK5_ORYSJ CBL-interacting protein kinase 5 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK5 PE=2 SV=1 Length=461 Score = 228 bits (581), Expect = 6e-64, Method: Composition-based stats. Identities = 60/268 (22%), Positives = 112/268 (42%), Gaps = 26/268 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960 LG+G F KV Y N + + VA+K + + + K+EI I+R + H +I+ Sbjct 18 LGQGTFAKV----YHARNLASNQSVAIKVIDKEKVLRVGMIDQIKREISIMRLVRHPNIV 73 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + + + + MEYV G L + R + + QQ+ + + H++ Sbjct 74 QLHEVMASKSK--IYFAMEYVRGGELFSRVARGRLKEDAARKYFQQLIGAVDFCHSRGVY 131 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 HRDL N+L+D + +K+ DFGL+ + + +P + APE + + + Sbjct 132 HRDLKPENLLVDENGNLKVSDFGLSAFKECQKQDGLLHTTCGTPA-YVAPEIINKRGYDG 190 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS GV L+ LL ++ + + +G+ + P Sbjct 191 AKADIWSCGVILFVLLAGYLPFHD---------------SNLMEMYRKISKGD-VKFPQW 234 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 +V L+ + + R T E L+ Sbjct 235 FTTDVRRLLSRLLDPNPNIRITVEKLVE 262 Score = 184 bits (468), Expect = 6e-49, Method: Composition-based stats. Identities = 58/331 (18%), Positives = 102/331 (31%), Gaps = 45/331 (14%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + LGQGT VY R+ V +KV Sbjct 7 ILMNRYELGRMLGQGTFAKVYHA------------------------RNLASNQSVAIKV 42 Query 644 LDPSHH---DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 +D + S+M V H ++ +H V + EYV G L R Sbjct 43 IDKEKVLRVGMIDQIKREISIMRLVRHPNIVQLHEVMASKSKIYFAMEYVRGGELFS--R 100 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 RG + QQL A+ + ++ + H ++ N+L+ G +K+SD Sbjct 101 VARGRLKEDAARKYFQQLIGAVDFCHSRGVYHRDLKPENLLVDENG-------NLKVSDF 153 Query 761 GVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ ++ ++APE + D W G L + G P Sbjct 154 GLSAFKECQKQDGLLHTTCGTPAYVAPEIINKRGYD-GAKADIWSCGVIL-FVLLAGYLP 211 Query 815 LQSRSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 + E + + P+ + L S+ L P R + ++ + + Sbjct 212 FHDSNLMEMYRKISKGDVKFPQWFTTDVRRLLSRLLDPNPNIRITVEKLVEHPWFKKGYK 271 Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 A +L+ +S K + Sbjct 272 PAVMLSQPNESNNLKDVHTAFSADHKDNEGK 302 >sp|P11345|RAF1_RAT RAF proto-oncogene serine/threonine-protein kinase OS=Rattus norvegicus OX=10116 GN=Raf1 PE=1 SV=1 Length=648 Score = 233 bits (594), Expect = 6e-64, Method: Composition-based stats. Identities = 81/333 (24%), Positives = 135/333 (41%), Gaps = 35/333 (11%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 + T P+ R + + +S + +G G F Sbjct 305 WSQPKTPVPAQRERAPGSGT----QEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF 360 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 G V + VAVK LK D P+ ++ E+ +LR H +I+ + G Sbjct 361 GTVYKGKWHG-------DVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILLFMGYM- 412 Query 968 DQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ IHRD+ Sbjct 413 --TKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMK 470 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYAS 1082 + N+ L VKIGDFGLA +V E V W APE ++ F + S Sbjct 471 SNNIFLHEGLTVKIGDFGLATVKSRWSGSQQV-EQPTGSVLWMAPEVIRMQDNNPFSFQS 529 Query 1083 DVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 DV+S+G+ LYEL+T + + ++G + RL + C Sbjct 530 DVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSRLYK------------NC 577 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 P + L+ +C + RP F ++ ++ + Sbjct 578 PKAMKRLVADCVKKVKEERPLFPQILSSIELLQ 610 Score = 223 bits (569), Expect = 1e-60, Method: Composition-based stats. Identities = 70/367 (19%), Positives = 127/367 (35%), Gaps = 62/367 (17%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 R + N I RG R S + ++ E+ + +G G+ VY+G+ Sbjct 316 RERAPGSGTQEKNKIRPRGQRDSSY--------YWEIEASEVMLSTRIGSGSFGTVYKGK 367 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQ 664 + V +K+L DP+ + AF +++ + Sbjct 368 WHGD---------------------------VAVKILKVVDPTPEQLQ-AFRNEVAVLRK 399 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 H ++ G + +VT++ E L L + M + +A+Q A + Y Sbjct 400 TRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778 L KN++H ++ NI L +K+ D G+ G+ E+ + W Sbjct 459 LHAKNIIHRDMKSNNIFLHEGL-------TVKIGDFGLATVKSRWSGSQQVEQPTGSVLW 511 Query 779 LAPECLPGGA-NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------ 831 +APE + N S D + +G L E+ GE P + ++ F + Sbjct 512 MAPEVIRMQDNNPFSFQSDVYSYGIVLYELM-TGELPYSHINNRDQIIFMVGRGYASPDL 570 Query 832 -RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 RL + + L + C+ +RP F IL + LQ + + S Sbjct 571 SRLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAH 630 Query 891 VFHKRYL 897 Sbjct 631 TEDINAC 637 >sp|Q9SNA3|Y3463_ARATH Putative receptor-like protein kinase At3g46340 OS=Arabidopsis thaliana OX=3702 GN=At3g46340 PE=1 SV=1 Length=889 Score = 238 bits (607), Expect = 6e-64, Method: Composition-based stats. Identities = 70/344 (20%), Positives = 132/344 (38%), Gaps = 17/344 (5%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 +P+ ++ + + R LGEG FG Sbjct 538 KKKPSNLEDLPPSSNTPRENITSTSISDTSIETKRKRFSYSEVMEMTKNLQRPLGEGGFG 597 Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 V +G+ + VAVK L + Q +K E+++L ++H +++ G C+++ Sbjct 598 VVYHGDI----NGSSQQVAVK-LLSQSSTQGYKEFKAEVELLLRVHHINLVSLVGYCDER 652 Query 970 GEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLH---AQHYIHR 1022 L L+ EY+ L+ +L + L A G+ YLH +HR Sbjct 653 DH--LALIYEYMSNKDLKHHLSGKHGGSVLKWNTRLQIAVDAALGLEYLHIGCRPSMVHR 710 Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082 D+ + N+LLD+ K+ DFGL+++ G E +P + PE + + S Sbjct 711 DVKSTNILLDDQFTAKMADFGLSRSFQLGDESQVSTVVAGTP-GYLDPEYYRTGRLAEMS 769 Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 DV+SFG+ L E++T+ P + + + +T +++ + + Sbjct 770 DVYSFGIVLLEIITNQRVI-DPAREKSHITEWTAFMLNRGDITRIMDPNLQGDYNSRSVW 828 Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKT-VHEKYQGQAPSVFS 1185 L C + RP+ ++ LK + + + Q S Sbjct 829 RALELAMMCANPSSEKRPSMSQVVIELKECIRSENKTQGMDSHS 872 Score = 208 bits (530), Expect = 4e-54, Method: Composition-based stats. Identities = 68/337 (20%), Positives = 106/337 (31%), Gaps = 59/337 (18%) Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 P I + + S+ V + LG+G VY G + Sbjct 548 PPSSNTPRENITSTSISDTSIETKRKRFSYSEVMEMTKNLQRPLGEGGFGVVYHGDI--- 604 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 G +V +K+L S F L+ +V H +L Sbjct 605 ---------------------NGSSQQVAVKLLSQSSTQGYKEFKAEVELLLRVHHINLV 643 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE--- 726 + G C ++ EY+ + L L + G + W ++ +A A L YL Sbjct 644 SLVGYCDERDHLALIYEYMSNKDLKHHLSGKHGGSVLKWNTRLQIAVDAALGLEYLHIGC 703 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLA 780 ++VH +V NILL A K++D G+ +E +L Sbjct 704 RPSMVHRDVKSTNILLDDQFTA-------KMADFGLSRSFQLGDESQVSTVVAGTPGYLD 756 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS---EKEHFYQRQHRLPEPS 837 PE G L+ D + FG LLEI + +R S E F + + Sbjct 757 PEYYRTG--RLAEMSDVYSFGIVLLEIITNQRVIDPAREKSHITEWTAFMLNRGDITRIM 814 Query 838 CPQL------------ATLTSQCLTYEPTQRPSFRTI 862 P L L C +RPS + Sbjct 815 DPNLQGDYNSRSVWRALELAMMCANPSSEKRPSMSQV 851 >sp|P93050|RKF3_ARATH Probable LRR receptor-like serine/threonine-protein kinase RKF3 OS=Arabidopsis thaliana OX=3702 GN=RKF3 PE=2 SV=1 Length=617 Score = 232 bits (592), Expect = 7e-64, Method: Composition-based stats. Identities = 72/288 (25%), Positives = 126/288 (44%), Gaps = 20/288 (7%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 + +G G +G V G VA K K +C + + E++++ ++ Sbjct 281 NNFSRHNIIGRGGYGNVFKGAL-----PDGTQVAFKRFK-NCSAGGDANFAHEVEVIASI 334 Query 955 YHEHIIKYKGCCED----QGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQI 1007 H +++ +G C +G + + +V + V GSL D+L + A + Sbjct 335 RHVNLLALRGYCTATTPYEGHQRI-IVCDLVSNGSLHDHLFGDLEAQLAWPLRQRIALGM 393 Query 1008 CEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 G+AYLH IHRD+ A N+LLD K+ DFGLAK PEG + R G Sbjct 394 ARGLAYLHYGAQPSIIHRDIKASNILLDERFEAKVADFGLAKFNPEGMTHMSTRVAG--T 451 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLR 1123 + + APE + SDV+SFGV L ELL+ + + + + + A + + Sbjct 452 MGYVAPEYALYGQLTEKSDVYSFGVVLLELLSRRKAIVTDEEGQPVSVADWAWSLVREGQ 511 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +++E G P + + + C + RPT + ++ +L++ Sbjct 512 TLDVVEDGMPEKGPPEVLEKYVLIAVLCSHPQLHARPTMDQVVKMLES 559 Score = 197 bits (501), Expect = 5e-52, Method: Composition-based stats. Identities = 67/385 (17%), Positives = 126/385 (33%), Gaps = 68/385 (18%) Query 554 QPGETSNLIIMRGARAS-PRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRV 610 +P +TS + S + L + SF + ++ + +G+G NV++G L Sbjct 245 KPRDTSLEAGTQSRLDSMSESTTLVKFSFDEIKKATNNFSRHNIIGRGGYGNVFKGALPD 304 Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670 +V K F +++ + H +L Sbjct 305 G-------------------------TQVAFKRFKNCSAGGDANFAHEVEVIASIRHVNL 339 Query 671 AFVHGVCV-----RGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSY 724 + G C G + I+V + V +G L L + + + +A +A L+Y Sbjct 340 LALRGYCTATTPYEGHQRIIVCDLVSNGSLHDHLFGDLEAQLAWPLRQRIALGMARGLAY 399 Query 725 LE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----GALSREERV-ERI 776 L +++H ++ NILL A K++D G+ G RV + Sbjct 400 LHYGAQPSIIHRDIKASNILLDERFEA-------KVADFGLAKFNPEGMTHMSTRVAGTM 452 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE-------------APLQSRSPSEK 823 ++APE G L+ D + FG LLE+ + A E Sbjct 453 GYVAPEYALYG--QLTEKSDVYSFGVVLLELLSRRKAIVTDEEGQPVSVADWAWSLVREG 510 Query 824 EHFYQRQHRLPEPSCPQLAT----LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 + + +PE P++ + C + RP+ +++ L + +A Sbjct 511 QTLDVVEDGMPEKGPPEVLEKYVLIAVLCSHPQLHARPTMDQVVKMLESNEFTVIAIPQR 570 Query 880 VNPDSPASDPTVFHKRYLKKIRDLG 904 P + L Sbjct 571 PIPLVACREEIDRSVSSSSGSGKLT 595 >sp|Q5R8X7|M3K13_PONAB Mitogen-activated protein kinase kinase kinase 13 OS=Pongo abelii OX=9601 GN=MAP3K13 PE=2 SV=1 Length=966 Score = 239 bits (609), Expect = 7e-64, Method: Composition-based stats. Identities = 83/301 (28%), Positives = 121/301 (40%), Gaps = 35/301 (12%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + + + D + +++ LG G G V L + E VA+K Sbjct 142 WNIIGKAYATDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRA------EEVAIK 195 Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 ++ I LR L H +II +KG C ++MEY G L + L Sbjct 196 KVREQNETD--------IKHLRKLKHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVL 245 Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 I L+ ++ I GM YLH IHRDL + NVL+ + VKI DFG +K + Sbjct 246 RAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELS 305 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 + + V W APE ++ D+WSFGV L+ELLT P K + Sbjct 306 D----KSTKMSFAGTVAWLAPEVIRNEPVSEKVDIWSFGVVLWELLTG-----EIPYKDV 356 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + I G + LP P CP LMK W+++ RP+F + L Sbjct 357 DSSAIIWGVGSN---------SLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQTLMHL 407 Query 1170 K 1170 Sbjct 408 D 408 Score = 211 bits (538), Expect = 6e-55, Method: Composition-based stats. Identities = 66/305 (22%), Positives = 109/305 (36%), Gaps = 50/305 (16%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 +A L Q V +EI++L LG G + V+ G+ R E Sbjct 146 GKAYATDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAE--------------- 190 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 V +K + + + ++ H ++ GVC + P ++ Sbjct 191 -----------EVAIKKVREQNE-------TDIKHLRKLKHPNIIAFKGVCTQAPCYCII 232 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 EY HG L LR R + + + +AS ++YL ++H ++ N+L+ Sbjct 233 MEYCAHGQLYEVLRAGR-KITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTD 291 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +K+SD G + ++ + WLAPE + +S +D W FG Sbjct 292 A-------VKISDFGTSKELSDKSTKMSFAGTVAWLAPEVIRN--EPVSEKVDIWSFGVV 342 Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 L E+ GE P + S +P L Q +P RPSFR Sbjct 343 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFR 401 Query 861 TILRD 865 L Sbjct 402 QTLMH 406 >sp|Q852Q2|OSK1_ORYSJ Serine/threonine protein kinase OSK1 OS=Oryza sativa subsp. japonica OX=39947 GN=OSK1 PE=1 SV=1 Length=505 Score = 229 bits (584), Expect = 7e-64, Method: Composition-based stats. Identities = 76/268 (28%), Positives = 111/268 (41%), Gaps = 30/268 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEHI 959 LG G FGKV + + TG VA+K L + + K+EI ILR H HI Sbjct 19 TLGIGSFGKVKI----AEHILTGHKVAIKILNRRKIKSMEMEEKVKREIKILRLFMHPHI 74 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I+ + + + +VMEYV G L DY+ + + + F QQI G+ Y H Sbjct 75 IRLYEVIDTPAD--IYVVMEYVKSGELFDYIVEKGRLQEEEARRFFQQIISGVEYCHRNM 132 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRDL N+LLD+ VKI DFGL+ + +G + ++ SP + APE + + Sbjct 133 VVHRDLKPENLLLDSKCNVKIADFGLSNVMRDG---HFLKTSCGSPN-YAAPEVISGKLY 188 Query 1079 -YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 DVWS GV LY LL + L + ++ G P Sbjct 189 AGPEVDVWSCGVILYALLCGTLPFDDE---------------NIPNLFKKIKGGI-YTLP 232 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165 L+ + R T + Sbjct 233 SHLSPLARDLIPRMLVVDPMKRITIREI 260 Score = 180 bits (456), Expect = 5e-47, Method: Composition-based stats. Identities = 49/321 (15%), Positives = 94/321 (29%), Gaps = 39/321 (12%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP--- 646 LG G+ V + G +V +K+L+ Sbjct 15 RIGKTLGIGSFGKVKIAEHILTGH------------------------KVAIKILNRRKI 50 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 ++ ++ H H+ ++ V + +V EYV+ G L ++ E+G + Sbjct 51 KSMEMEEKVKREIKILRLFMHPHIIRLYEVIDTPADIYVVMEYVKSGELFDYI-VEKGRL 109 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--- 763 QQ+ S + Y +VH ++ N+LL +K++D G+ Sbjct 110 QEEEARRFFQQIISGVEYCHRNMVVHRDLKPENLLLDSKC-------NVKIADFGLSNVM 162 Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + + APE + G + +D W G L + P+ Sbjct 163 RDGHFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYALLCGTLPFDDENIPNLF 221 Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 + + LP P L + L +P +R + R I + Sbjct 222 KKIKGGIYTLPSHLSPLARDLIPRMLVVDPMKRITIREIREHQWFTVGLPRYLAVPPPDT 281 Query 884 SPASDPTVFHKRYLKKIRDLG 904 + Sbjct 282 AQQVKKLDDETLNDVINMGFD 302 >sp|C0LGP2|MEE39_ARATH Probable LRR receptor-like serine/threonine-protein kinase MEE39 OS=Arabidopsis thaliana OX=3702 GN=MEE39 PE=1 SV=1 Length=878 Score = 238 bits (606), Expect = 7e-64, Method: Composition-based stats. Identities = 66/293 (23%), Positives = 118/293 (40%), Gaps = 16/293 (5%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 + + R LGEG FG V + + E VAVK L + Q +K Sbjct 555 RFTYSEVMEMTKNLQRPLGEGGFGVVYHGDLNGS-----EQVAVK-LLSQTSAQGYKEFK 608 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLL 1001 E+++L ++H +++ G C++Q L+ EY+ G L +L + L Sbjct 609 AEVELLLRVHHINLVNLVGYCDEQDH--FALIYEYMSNGDLHQHLSGKHGGSVLNWGTRL 666 Query 1002 LFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 A + G+ YLH +HRD+ + N+LLD + KI DFGL+++ G + +V Sbjct 667 QIAIEAALGLEYLHTGCKPAMVHRDVKSTNILLDEEFKAKIADFGLSRSFQVGGDQSQVS 726 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 + + PE + SDV+SFG+ L E++T+ + + Sbjct 727 TVVAGTLGYLDPEYYLTSELSEKSDVYSFGILLLEIITNQRVIDQT-RENPNIAEWVTFV 785 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + +++++ + +C + RP +I LK Sbjct 786 IKKGDTSQIVDPKLHGNYDTHSVWRALEVAMSCANPSSVKRPNMSQVIINLKE 838 Score = 210 bits (535), Expect = 9e-55, Method: Composition-based stats. Identities = 63/320 (20%), Positives = 109/320 (34%), Gaps = 61/320 (19%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 + ++ V + LG+G VY G L Sbjct 554 KRFTYSEVMEMTKNLQRPLGEGGFGVVYHGDLNGSE------------------------ 589 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +V +K+L + F L+ +V H +L + G C ++ EY+ +G L Sbjct 590 -QVAVKLLSQTSAQGYKEFKAEVELLLRVHHINLVNLVGYCDEQDHFALIYEYMSNGDLH 648 Query 697 VWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGT 751 L + G + W ++ +A + A L YL +VH +V NILL A Sbjct 649 QHLSGKHGGSVLNWGTRLQIAIEAALGLEYLHTGCKPAMVHRDVKSTNILLDEEFKA--- 705 Query 752 SPFIKLSDPGVGLG-------ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 K++D G+ + + +L PE + LS D + FG L Sbjct 706 ----KIADFGLSRSFQVGGDQSQVSTVVAGTLGYLDPEYYLT--SELSEKSDVYSFGILL 759 Query 805 LEICFDGEAPLQSRSP---SEKEHFYQRQHRLPEPSCPQLA------------TLTSQCL 849 LEI + Q+R +E F ++ + P+L + C Sbjct 760 LEIITNQRVIDQTRENPNIAEWVTFVIKKGDTSQIVDPKLHGNYDTHSVWRALEVAMSCA 819 Query 850 TYEPTQRPSFRTILRDLTRL 869 +RP+ ++ +L Sbjct 820 NPSSVKRPNMSQVIINLKEC 839 >sp|Q9SEZ7|CIPKG_ARATH CBL-interacting serine/threonine-protein kinase 16 OS=Arabidopsis thaliana OX=3702 GN=CIPK16 PE=1 SV=1 Length=469 Score = 228 bits (581), Expect = 7e-64, Method: Composition-based stats. Identities = 68/275 (25%), Positives = 114/275 (41%), Gaps = 35/275 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR---SGWKQEIDILRTLYHEHI 959 LG G+F KV Y T TG+ VA+K +K D + R ++EI ++R L H ++ Sbjct 21 LGTGNFAKV----YHGTEISTGDDVAIKVIKKDHVFKRRGMMEQIEREIAVMRLLRHPNV 76 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ + + K + VMEYV G L + + R + + QQ+ + + H++ Sbjct 77 VELREVMATK--KKIFFVMEYVNGGELFEMIDRDGKLPEDLARKYFQQLISAVDFCHSRG 134 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE-------GHEYYRVREDGDSPVFWYAPE 1071 HRD+ N+LLD + +K+ DFGL+ + G + +P + APE Sbjct 135 VFHRDIKPENLLLDGEGDLKVTDFGLSALMMPEGLGGRRGSSDDLLHTRCGTPA-YVAPE 193 Query 1072 CLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 L+ + A +D+WS G+ LY LL I + MT+ E Sbjct 194 VLRNKGYDGAMADIWSCGIVLYALLAGFLPF------------IDENVMTLYTKIFKAE- 240 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P E L+ + R + + Sbjct 241 ---CEFPPWFSLESKELLSRLLVPDPEQRISMSEI 272 Score = 181 bits (459), Expect = 1e-47, Method: Composition-based stats. Identities = 58/342 (17%), Positives = 103/342 (30%), Gaps = 50/342 (15%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 V + LG G VY G G V +K Sbjct 9 TVLFDKYNIGRLLGTGNFAKVYHGTEISTGDD------------------------VAIK 44 Query 643 VLDPSH----HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V+ H + ++M + H ++ + V + V EYV G L Sbjct 45 VIKKDHVFKRRGMMEQIEREIAVMRLLRHPNVVELREVMATKKKIFFVMEYVNGGELFEM 104 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + G +P QQL SA+ + ++ + H ++ N+LL G +K++ Sbjct 105 I-DRDGKLPEDLARKYFQQLISAVDFCHSRGVFHRDIKPENLLLDGEGD-------LKVT 156 Query 759 DPGVG-----------LGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 D G+ G+ R ++APE L D W G L Sbjct 157 DFGLSALMMPEGLGGRRGSSDDLLHTRCGTPAYVAPEVLRNKGYD-GAMADIWSCGIVLY 215 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + + + ++ + P + L S+ L +P QR S I Sbjct 216 ALLAGFLPFIDENVMTLYTKIFKAECEFPPWFSLESKELLSRLLVPDPEQRISMSEIKMI 275 Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 + + +++ P+ K+ +G Sbjct 276 PWFRKNFTPSVAFSIDETIPSPPEPPTKKKKKDLNEKEDDGA 317 >sp|Q9M2Z1|BAME2_ARATH Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM2 OS=Arabidopsis thaliana OX=3702 GN=BAM2 PE=1 SV=1 Length=1002 Score = 239 bits (610), Expect = 8e-64, Method: Composition-based stats. Identities = 81/312 (26%), Positives = 126/312 (40%), Gaps = 17/312 (5%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 L+ + A + LK+ +G+G G V G++VA Sbjct 662 LRNASEAKAWRLTAFQRLDFTCDDVLDSLKEDNIIGKGGAGIVYKGTMPK-----GDLVA 716 Query 929 VKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 VK L G H G+ EI L + H HI++ G C + LV EY+P GSL Sbjct 717 VKRLATMSHGSSHDHGFNAEIQTLGRIRHRHIVRLLGFCSNHETN--LLVYEYMPNGSLG 774 Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGD 1041 + L + A + +G+ YLH +HRD+ + N+LLD++ + D Sbjct 775 EVLHGKKGGHLHWNTRYKIALEAAKGLCYLHHDCSPLIVHRDVKSNNILLDSNFEAHVAD 834 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLAK + + + S + APE K SDV+SFGV L EL+T Sbjct 835 FGLAKFLQDSGTSECMSAIAGS-YGYIAPEYAYTLKVDEKSDVYSFGVVLLELITGKKPV 893 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERL-PRPDKCPCEVYHLMKNCWETEASFRP 1160 ++++ + + L RL P V+++ C E +A RP Sbjct 894 GE-FGDGVDIVQWVRSMTDSNKDCVLKVIDLRLSSVPVHEVTHVFYVALLCVEEQAVERP 952 Query 1161 TFENLIPILKTV 1172 T ++ IL + Sbjct 953 TMREVVQILTEI 964 Score = 196 bits (499), Expect = 6e-50, Method: Composition-based stats. Identities = 64/345 (19%), Positives = 119/345 (34%), Gaps = 70/345 (20%) Query 561 LIIMRGARASPRTLNLSQLSFHRVDQ------KEITQLSHLGQGTRTNVYEGRLRVEGSG 614 +I R R + +F R+D + + + +G+G VY+G + Sbjct 656 IIKARSLRNASEAKAWRLTAFQRLDFTCDDVLDSLKEDNIIGKGGAGIVYKGTMPKGD-- 713 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAF 672 V +K L H + F + ++ H H+ Sbjct 714 -----------------------LVAVKRLATMSHGSSHDHGFNAEIQTLGRIRHRHIVR 750 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKN-- 729 + G C N++V EY+ +G L L ++ GH+ + +A + A L YL + Sbjct 751 LLGFCSNHETNLLVYEYMPNGSLGEVLHGKKGGHLHWNTRYKIALEAAKGLCYLHHDCSP 810 Query 730 -LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPE 782 +VH +V NILL ++ ++D G+ ++APE Sbjct 811 LIVHRDVKSNNILLD-------SNFEAHVADFGLAKFLQDSGTSECMSAIAGSYGYIAPE 863 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAP-----------LQSRSPSEKEH------ 825 + D + FG LLE+ G+ P RS ++ Sbjct 864 YA--YTLKVDEKSDVYSFGVVLLELI-TGKKPVGEFGDGVDIVQWVRSMTDSNKDCVLKV 920 Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 R +P + + C+ + +RP+ R +++ LT + Sbjct 921 IDLRLSSVPVHEVTHVFYVALLCVEEQAVERPTMREVVQILTEIP 965 >sp|Q6PA14|STK4_XENLA Serine/threonine-protein kinase 4 OS=Xenopus laevis OX=8355 GN=stk4 PE=2 SV=1 Length=485 Score = 228 bits (582), Expect = 8e-64, Method: Composition-based stats. Identities = 63/270 (23%), Positives = 112/270 (41%), Gaps = 31/270 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V Y ++ T ++VA+K + + Q +EI I++ H++K Sbjct 35 KLGEGSYGSV----YKASHKETSQIVAIKQIPVESDLQ---EIIKEISIMQQCDSPHVVK 87 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VME+ GS+ D L + ++ ++ Q +G+ YLH Sbjct 88 YYGSYFKNTD--LWIVMEFCGGGSVSDIIRLRKQTLNEDEIATILQSTLKGLEYLHFMRK 145 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL + K+ DFG+A + + R FW APE ++E + Sbjct 146 IHRDIKAGNILLSCEGTAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP--RP 1137 +D+WS G+T E+ ++ +R ++ +P Sbjct 203 CVADIWSLGITAIEMAEGKPP---------------YAEIHPMRAIFMIPSNPPPTFRKP 247 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + + C R + L+ Sbjct 248 ELWSKDFVDFINLCLVKNPELRSSATELLQ 277 Score = 200 bits (508), Expect = 6e-54, Method: Composition-based stats. Identities = 58/300 (19%), Positives = 99/300 (33%), Gaps = 44/300 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 LS+ S ++ ++ L LG+G+ +VY+ + Sbjct 17 LSEESLNKQPEEVFDVLEKLGEGSYGSVYKASHKE------------------------T 52 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K + + S+M Q H+ +G + + +V E+ G + Sbjct 53 SQIVAIKQIPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEFCGGGSV 110 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + + Q L YL +H ++ NILL+ G A Sbjct 111 SDIIRLRKQTLNEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLSCEGTA------- 163 Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D GV R + W+APE + + D W G T +E+ +G Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220 Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P P R PE + CL P R S +L+ Sbjct 221 KPPYAEIHPMRAIFMIPSNPPPTFRKPELWSKDFVDFINLCLVKNPELRSSATELLQHPF 280 >sp|Q8GX23|PERK5_ARATH Proline-rich receptor-like protein kinase PERK5 OS=Arabidopsis thaliana OX=3702 GN=PERK5 PE=2 SV=1 Length=670 Score = 233 bits (595), Expect = 9e-64, Method: Composition-based stats. Identities = 88/348 (25%), Positives = 135/348 (39%), Gaps = 31/348 (9%) Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910 +P P P A L N + D + LG+G FG Sbjct 266 QQPVSGPHSDASNLTGRTAIPSPQAATLGHNQSTFTYDELSIATEGFAQSNLLGQGGFGY 325 Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970 V +G+ VAVK+LK G R ++ E+DI+ ++H H++ G C G Sbjct 326 VHKGVL-----PSGKEVAVKSLKLGSGQGERE-FQAEVDIISRVHHRHLVSLVGYCISGG 379 Query 971 EKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDL 1024 ++ LV E++P +L +L R + + A G+AYLH IHRD+ Sbjct 380 QR--LLVYEFIPNNTLEFHLHGKGRPVLDWPTRVKIALGSARGLAYLHEDCHPRIIHRDI 437 Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084 A N+LLD K+ DFGLAK + + + R + APE K SDV Sbjct 438 KAANILLDFSFETKVADFGLAKLSQDNYTHVSTR--VMGTFGYLAPEYASSGKLSDKSDV 495 Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG----QMTVLRLTELLERGERLPRPDKC 1140 +SFGV L EL+T L+ A+ +L + L + Sbjct 496 FSFGVMLLELITGRPPLDLTGEMEDSLVDWARPLCLKAAQDGDYNQLADPRLELNYSHQ- 554 Query 1141 PCEVYHLMKNC----WETEASFRPTFENLIPILK---TVHEKYQGQAP 1181 E+ M +C A RP ++ L+ ++ + +G P Sbjct 555 --EMVQ-MASCAAAAIRHSARRRPKMSQIVRALEGDMSMDDLSEGTRP 599 Score = 225 bits (574), Expect = 5e-61, Method: Composition-based stats. Identities = 70/359 (19%), Positives = 120/359 (33%), Gaps = 61/359 (17%) Query 488 AQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSL 547 ++S + M + +G + + G + Sbjct 216 KKKSPQVNHMHYYNNNPYGGAPSGNGGYYKGTPQDHVV----------NMAGQGGGNWGP 265 Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNL----SQLSFHR--VDQKEITQLSHLGQGTRT 601 ++ + SNL R A SP+ L S ++ + + Q + LGQG Sbjct 266 QQPVSGPHSDASNLT-GRTAIPSPQAATLGHNQSTFTYDELSIATEGFAQSNLLGQGGFG 324 Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL 661 V++G L V +K L F + Sbjct 325 YVHKGVLPSGK-------------------------EVAVKSLKLGSGQGEREFQAEVDI 359 Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLAS 720 +S+V H HL + G C+ G + ++V E++ + L+ L + R + ++ +A A Sbjct 360 ISRVHHRHLVSLVGYCISGGQRLLVYEFIPNNTLEFHLHGKGRPVLDWPTRVKIALGSAR 419 Query 721 ALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV---- 773 L+YL ++H ++ NILL S K++D G+ + V Sbjct 420 GLAYLHEDCHPRIIHRDIKAANILLD-------FSFETKVADFGLAKLSQDNYTHVSTRV 472 Query 774 -ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 +LAPE G LS D + FG LLE+ G PL E + Sbjct 473 MGTFGYLAPEYASSG--KLSDKSDVFSFGVMLLELI-TGRPPLDLTGEMEDSLVDWARP 528 >sp|O22834|LRK53_ARATH Probable L-type lectin-domain containing receptor kinase V.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK53 PE=3 SV=1 Length=664 Score = 233 bits (594), Expect = 9e-64, Method: Composition-based stats. Identities = 78/324 (24%), Positives = 123/324 (38%), Gaps = 21/324 (6%) Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920 + + + + V + LGEG FG V + T Sbjct 299 IVFFYKRHKKLLEVLEEWEVECGPHRFSYKELFNATNGFKQLLGEGGFGPV----FKGTL 354 Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 G+ +AVK + D R EI + L H ++++ G C + E L LV ++ Sbjct 355 SGSNAKIAVKRVSHDSSQGMRE-LLAEISTIGRLRHPNLVRLLGYCRYKEE--LYLVYDF 411 Query 981 VPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQHY---IHRDLAARNVLLDN 1033 +P GSL YL + + +Q + + ++YLH IHRD+ NVL+D+ Sbjct 412 LPNGSLDKYLYGTSDQKQLSWSQRFKIIKDVASALSYLHHGWIHVVIHRDIKPANVLIDD 471 Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 +GDFGLAK +G++ R G + APE ++ + +DV++FG+ + E Sbjct 472 KMNASLGDFGLAKVYDQGYDPQTSRVAG--TFGYMAPEIMRTGRPTMGTDVYAFGMFMLE 529 Query 1094 LLTHCDSSQSPPTKFLE---LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 + CD P E L A + E R V L Sbjct 530 V--SCDRKLFEPRAESEEAILTNWAINCWENGDIVEAATERIRQDNDKGQLELVLKLGVL 587 Query 1151 CWETEASFRPTFENLIPILKTVHE 1174 C RP ++ IL V E Sbjct 588 CSHEAEEVRPDMATVVKILNGVSE 611 Score = 207 bits (528), Expect = 4e-55, Method: Composition-based stats. Identities = 46/263 (17%), Positives = 92/263 (35%), Gaps = 43/263 (16%) Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 S+ + LG+G V++G L G + Sbjct 325 FSYKELFNATNGFKQLLGEGGFGPVFKGTL------------------------SGSNAK 360 Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 + +K + S + ++ H +L + G C E +V +++ +G LD + Sbjct 361 IAVKRVSHDSSQGMRELLAEISTIGRLRHPNLVRLLGYCRYKEELYLVYDFLPNGSLDKY 420 Query 699 LR--RERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSP 753 L ++ + + + + + +ASALSYL + ++H ++ N+L+ A Sbjct 421 LYGTSDQKQLSWSQRFKIIKDVASALSYLHHGWIHVVIHRDIKPANVLIDDKMNAS---- 476 Query 754 FIKLSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 L D G+ ++APE + G ++ T D + FG +LE+ Sbjct 477 ---LGDFGLAKVYDQGYDPQTSRVAGTFGYMAPEIMRTGRPTMGT--DVYAFGMFMLEVS 531 Query 809 FDGEAPLQSRSPSEKEHFYQRQH 831 D + E + Sbjct 532 CDRKLFEPRAESEEAILTNWAIN 554 >sp|O04086|Y1105_ARATH Probable receptor-like protein kinase At1g11050 OS=Arabidopsis thaliana OX=3702 GN=At1g11050 PE=2 SV=1 Length=625 Score = 232 bits (592), Expect = 9e-64, Method: Composition-based stats. Identities = 75/296 (25%), Positives = 122/296 (41%), Gaps = 28/296 (9%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 + +G G FG V G ++AVK + + Q + ++ E++I+ L Sbjct 293 NNFSQKNFIGRGGFGFVYKGVL-----PDGSVIAVKKV-IESEFQGDAEFRNEVEIISNL 346 Query 955 YHEHIIKYKGC--CEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQLLLFAQQ 1006 H +++ +GC +D E LV +Y+ G+L D+L + + Q Sbjct 347 KHRNLVPLRGCSMVDDDSESQRYLVYDYMSNGNLDDHLFPRGETTKMPLSWPQRKSIILD 406 Query 1007 ICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 + +G+AYLH HRD+ N+LLD D ++ DFGLAK EG + R G Sbjct 407 VAKGLAYLHYGVKPAIYHRDIKGTNILLDVDMRARVADFGLAKQSREGESHLTTRVAG-- 464 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC---DSSQSPPTKFLELIGIAQGQMT 1120 + APE + SDV+SFGV + E++ D S S + A + Sbjct 465 THGYLAPEYALYGQLTEKSDVYSFGVVILEIMCGRKALDLSTSGSPNTFLITDWAWSLVK 524 Query 1121 VLRLTELLER------GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + E LE+ G L P + C + RPT + + +L+ Sbjct 525 AGKTEEALEQSLLREEGSGLSNPKGIMERFLQVGILCAHVLVALRPTILDALKMLE 580 Score = 201 bits (512), Expect = 2e-53, Method: Composition-based stats. Identities = 60/296 (20%), Positives = 106/296 (36%), Gaps = 51/296 (17%) Query 535 GCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL-SQLSFHRVDQKEITQLS 593 G L+ AG C R + GE + P T ++ ++ +Q + Sbjct 240 GALVIAGLICLYFRFGKAVKGGEVGWEDQGSRPKWRPNTGSIWFKIEELEKATNNFSQKN 299 Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 +G+G VY+G L + +K + S Sbjct 300 FIGRGGFGFVYKGVLPDGS-------------------------VIAVKKVIESEFQGDA 334 Query 654 AFYETASLMSQVSHTHLAFVHGVCV----RGPENIMVTEYVEHGPLDVWL--RRERGHVP 707 F ++S + H +L + G + + +V +Y+ +G LD L R E +P Sbjct 335 EFRNEVEIISNLKHRNLVPLRGCSMVDDDSESQRYLVYDYMSNGNLDDHLFPRGETTKMP 394 Query 708 MAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 ++W + + +A L+YL + H ++ G NILL +++D G+ Sbjct 395 LSWPQRKSIILDVAKGLAYLHYGVKPAIYHRDIKGTNILLD-------VDMRARVADFGL 447 Query 763 GLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 + E +LAPE G L+ D + FG +LEI +A Sbjct 448 AKQSREGESHLTTRVAGTHGYLAPEYALYG--QLTEKSDVYSFGVVILEIMCGRKA 501 >sp|Q9LPZ3|Y1141_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g11410 OS=Arabidopsis thaliana OX=3702 GN=At1g11410 PE=3 SV=3 Length=845 Score = 237 bits (604), Expect = 1e-63, Method: Composition-based stats. Identities = 77/283 (27%), Positives = 125/283 (44%), Gaps = 18/283 (6%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 LG G FG V G +AVK L G Q +K E+ ++ L Sbjct 521 NNFAFQNKLGAGGFGPVYKGVLQ-----NGMEIAVKRLSKSSG-QGMEEFKNEVKLISKL 574 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEG 1010 H ++++ GCC + EK LV EY+P SL ++ R + + + + I G Sbjct 575 QHRNLVRILGCCVEFEEK--MLVYEYLPNKSLDYFIFHEEQRAELDWPKRMGIIRGIGRG 632 Query 1011 MAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH IHRDL A NVLLDN+ + KI DFGLA+ G++ + Sbjct 633 ILYLHQDSRLRIIHRDLKASNVLLDNEMIPKIADFGLARIFG-GNQIEGSTNRVVGTYGY 691 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 +PE + +F SDV+SFGV + E++T +S + L L+ + E+ Sbjct 692 MSPEYAMDGQFSIKSDVYSFGVLILEIITGKRNSAF-YEESLNLVKHIWDRWENGEAIEI 750 Query 1128 LERGE-RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 +++ + + H+ C + +S RP +++ +L Sbjct 751 IDKLMGEETYDEGEVMKCLHIGLLCVQENSSDRPDMSSVVFML 793 Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats. Identities = 61/370 (16%), Positives = 113/370 (31%), Gaps = 61/370 (16%) Query 557 ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616 E S ++ ++ R L L +LS + LG G VY+G L+ Sbjct 491 EDSFILEELEDKSRSRELPLFELSTIATATNNFAFQNKLGAGGFGPVYKGVLQNG----- 545 Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676 + + +K L S F L+S++ H +L + G Sbjct 546 --------------------MEIAVKRLSKSSGQGMEEFKNEVKLISKLQHRNLVRILGC 585 Query 677 CVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLV 731 CV E ++V EY+ + LD ++ E + W +M + + + + YL ++ Sbjct 586 CVEFEEKMLVYEYLPNKSLDYFIFHEEQRAELDWPKRMGIIRGIGRGILYLHQDSRLRII 645 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLP 785 H ++ N+LL + K++D G+ S V +++PE Sbjct 646 HRDLKASNVLLDNEMIP-------KIADFGLARIFGGNQIEGSTNRVVGTYGYMSPEYAM 698 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEA-------------PLQSRSPSEKEHFYQRQH- 831 G S D + FG +LEI E + Sbjct 699 DG--QFSIKSDVYSFGVLILEIITGKRNSAFYEESLNLVKHIWDRWENGEAIEIIDKLMG 756 Query 832 --RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 E + + C+ + RP +++ L + + Sbjct 757 EETYDEGEVMKCLHIGLLCVQENSSDRPDMSSVVFMLGHNAIDLPSPKHPAFTAGRRRNT 816 Query 890 TVFHKRYLKK 899 Sbjct 817 KTGGSSDNWP 826 >sp|B9DFG5|PTI13_ARATH PTI1-like tyrosine-protein kinase 3 OS=Arabidopsis thaliana OX=3702 GN=PTI13 PE=1 SV=1 Length=408 Score = 226 bits (575), Expect = 1e-63, Method: Composition-based stats. Identities = 74/356 (21%), Positives = 125/356 (35%), Gaps = 35/356 (10%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV------------ 891 L C EP + + A Sbjct 47 LCCACHVEEPYHSSENEHLRSPKHHNDFGHHTRKPQAAVKPDALKEPPSIDVPALSLDEL 106 Query 892 -FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 +GEG +G+ G+ VAVK L P+ + ++ Sbjct 107 KEKTDNFGSKSLIGEGSYGRAYYATLK-----DGKAVAVKKLDNAAEPESNVEFLTQVSR 161 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------IGLAQL 1000 + L H++ ++ G C + + L E+ +GSL D L + Q Sbjct 162 VSKLKHDNFVELFGYCVEGNFRILA--YEFATMGSLHDILHGRKGVQGAQPGPTLDWIQR 219 Query 1001 LLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + A G+ YLH + IHRD+ + NVLL D KI DF L+ P+ Sbjct 220 VRIAVDAARGLEYLHEKVQPAVIHRDIRSSNVLLFEDFKAKIADFNLSNQSPD-MAARLH 278 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQ 1116 ++APE + SDV+SFGV L ELLT + P L+ A Sbjct 279 STRVLGTFGYHAPEYAMTGQLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWAT 338 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +++ ++ + ++ + P K ++ + C + E+ FRP ++ L+ + Sbjct 339 PRLSEDKVKQCVDPKLKGEYPPKAVAKLAAVAALCVQYESEFRPNMSIVVKALQPL 394 Score = 190 bits (482), Expect = 2e-51, Method: Composition-based stats. Identities = 55/306 (18%), Positives = 98/306 (32%), Gaps = 54/306 (18%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615 + A P ++++ LS + S +G+G+ Y L+ Sbjct 80 KPQAAVKPDALKEPPSIDVPALSLDELKEKTDNFGSKSLIGEGSYGRAYYATLKDGK--- 136 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVH 674 V +K LD + + + F S +S++ H + + Sbjct 137 ----------------------AVAVKKLDNAAEPESNVEFLTQVSRVSKLKHDNFVELF 174 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERG--------HVPMAWKMVVAQQLASALSYLE 726 G CV G I+ E+ G L L +G + ++ +A A L YL Sbjct 175 GYCVEGNFRILAYEFATMGSLHDILHGRKGVQGAQPGPTLDWIQRVRIAVDAARGLEYLH 234 Query 727 NK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG------LGALSREERVERIP 777 K ++H ++ N+LL K++D + L + Sbjct 235 EKVQPAVIHRDIRSSNVLLFE-------DFKAKIADFNLSNQSPDMAARLHSTRVLGTFG 287 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS 837 + APE G L+ D + FG LLE+ + + ++ RL E Sbjct 288 YHAPEYAMTG--QLTQKSDVYSFGVVLLELLTGRKPVDHTMPRGQQSLVTWATPRLSEDK 345 Query 838 CPQLAT 843 Q Sbjct 346 VKQCVD 351 >sp|Q5R5M7|RAF1_PONAB RAF proto-oncogene serine/threonine-protein kinase OS=Pongo abelii OX=9601 GN=RAF1 PE=2 SV=1 Length=648 Score = 233 bits (593), Expect = 1e-63, Method: Composition-based stats. Identities = 80/333 (24%), Positives = 136/333 (41%), Gaps = 35/333 (11%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 + T P+ R + + + +S + +G G F Sbjct 305 WSQPKTPVPAQRE----RAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF 360 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 G V + VAVK LK D P+ ++ E+ +LR H +I+ + G Sbjct 361 GTVYKGKWHG-------DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYM- 412 Query 968 DQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ IHRD+ Sbjct 413 --TKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMK 470 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYAS 1082 + N+ L VKIGDFGLA +V E V W APE ++ F + S Sbjct 471 SNNIFLHEGLTVKIGDFGLATVKSRWSGSQQV-EQPTGSVLWMAPEVIRMQDNNPFSFQS 529 Query 1083 DVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 DV+S+G+ LYEL+T + + ++G + +L + C Sbjct 530 DVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYK------------NC 577 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 P + L+ +C + RP F ++ ++ + Sbjct 578 PKAMKRLVADCVKKVKEERPLFPQILSSIELLQ 610 Score = 220 bits (561), Expect = 1e-59, Method: Composition-based stats. Identities = 69/367 (19%), Positives = 126/367 (34%), Gaps = 62/367 (17%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 R + N I RG R S + ++ E+ + +G G+ VY+G+ Sbjct 316 RERAPVSGTQEKNKIRPRGQRDSSY--------YWEIEASEVMLSTRIGSGSFGTVYKGK 367 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQ 664 + V +K+L DP+ AF +++ + Sbjct 368 WHGD---------------------------VAVKILKVVDPTPEQFQ-AFRNEVAVLRK 399 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 H ++ G + +VT++ E L L + M + +A+Q A + Y Sbjct 400 TRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778 L KN++H ++ NI L +K+ D G+ G+ E+ + W Sbjct 459 LHAKNIIHRDMKSNNIFLHEGL-------TVKIGDFGLATVKSRWSGSQQVEQPTGSVLW 511 Query 779 LAPECLPGGA-NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------ 831 +APE + N S D + +G L E+ GE P + ++ F + Sbjct 512 MAPEVIRMQDNNPFSFQSDVYSYGIVLYELM-TGELPYSHINNRDQIIFMVGRGYASPDL 570 Query 832 -RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 +L + + L + C+ +RP F IL + LQ + + S Sbjct 571 SKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAH 630 Query 891 VFHKRYL 897 Sbjct 631 TEDINAC 637 >sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens OX=9606 GN=RAF1 PE=1 SV=1 Length=648 Score = 233 bits (593), Expect = 1e-63, Method: Composition-based stats. Identities = 80/333 (24%), Positives = 136/333 (41%), Gaps = 35/333 (11%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 + T P+ R + + + +S + +G G F Sbjct 305 WSQPKTPVPAQRE----RAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF 360 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 G V + VAVK LK D P+ ++ E+ +LR H +I+ + G Sbjct 361 GTVYKGKWHG-------DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYM- 412 Query 968 DQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ IHRD+ Sbjct 413 --TKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMK 470 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYAS 1082 + N+ L VKIGDFGLA +V E V W APE ++ F + S Sbjct 471 SNNIFLHEGLTVKIGDFGLATVKSRWSGSQQV-EQPTGSVLWMAPEVIRMQDNNPFSFQS 529 Query 1083 DVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 DV+S+G+ LYEL+T + + ++G + +L + C Sbjct 530 DVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYK------------NC 577 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 P + L+ +C + RP F ++ ++ + Sbjct 578 PKAMKRLVADCVKKVKEERPLFPQILSSIELLQ 610 Score = 220 bits (561), Expect = 1e-59, Method: Composition-based stats. Identities = 69/367 (19%), Positives = 126/367 (34%), Gaps = 62/367 (17%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 R + N I RG R S + ++ E+ + +G G+ VY+G+ Sbjct 316 RERAPVSGTQEKNKIRPRGQRDSSY--------YWEIEASEVMLSTRIGSGSFGTVYKGK 367 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQ 664 + V +K+L DP+ AF +++ + Sbjct 368 WHGD---------------------------VAVKILKVVDPTPEQFQ-AFRNEVAVLRK 399 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 H ++ G + +VT++ E L L + M + +A+Q A + Y Sbjct 400 TRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778 L KN++H ++ NI L +K+ D G+ G+ E+ + W Sbjct 459 LHAKNIIHRDMKSNNIFLHEGL-------TVKIGDFGLATVKSRWSGSQQVEQPTGSVLW 511 Query 779 LAPECLPGGA-NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------ 831 +APE + N S D + +G L E+ GE P + ++ F + Sbjct 512 MAPEVIRMQDNNPFSFQSDVYSYGIVLYELM-TGELPYSHINNRDQIIFMVGRGYASPDL 570 Query 832 -RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 +L + + L + C+ +RP F IL + LQ + + S Sbjct 571 SKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAH 630 Query 891 VFHKRYL 897 Sbjct 631 TEDINAC 637 >sp|O64483|SIRK_ARATH Senescence-induced receptor-like serine/threonine-protein kinase OS=Arabidopsis thaliana OX=3702 GN=SIRK PE=1 SV=1 Length=876 Score = 237 bits (605), Expect = 1e-63, Method: Composition-based stats. Identities = 65/294 (22%), Positives = 122/294 (41%), Gaps = 16/294 (5%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 + R +G+G FGKV GE VAVK L + Q + Sbjct 562 RYFKYSEVVNITNNFERVIGKGGFGKVYHGVI------NGEQVAVKVLSEE-SAQGYKEF 614 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLL 1001 + E+D+L ++H ++ G C + + L+ EY+ +L DYL + + L Sbjct 615 RAEVDLLMRVHHTNLTSLVGYCNEINH--MVLIYEYMANENLGDYLAGKRSFILSWEERL 672 Query 1002 LFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 + +G+ YLH +HRD+ N+LL+ K+ DFGL+++ ++ Sbjct 673 KISLDAAQGLEYLHNGCKPPIVHRDVKPTNILLNEKLQAKMADFGLSRSFSV-EGSGQIS 731 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 + + PE + SDV+S GV L E++T + S T+ + + + Sbjct 732 TVVAGSIGYLDPEYYSTRQMNEKSDVYSLGVVLLEVITGQPAIASSKTEKVHISDHVRSI 791 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + + ++++ R ++ + C E ++ RPT ++ LK + Sbjct 792 LANGDIRGIVDQRLRERYDVGSAWKMSEIALACTEHTSAQRPTMSQVVMELKQI 845 Score = 202 bits (514), Expect = 4e-52, Method: Composition-based stats. Identities = 66/349 (19%), Positives = 114/349 (33%), Gaps = 65/349 (19%) Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 G R P + V +G+G VY G + E Sbjct 551 GERNGPLKTAKRYFKYSEVVNITNNFERVIGKGGFGKVYHGVINGE-------------- 596 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 +V +KVL F L+ +V HT+L + G C ++ Sbjct 597 ------------QVAVKVLSEESAQGYKEFRAEVDLLMRVHHTNLTSLVGYCNEINHMVL 644 Query 686 VTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNIL 741 + EY+ + L +L +R + ++ ++ A L YL N +VH +V NIL Sbjct 645 IYEYMANENLGDYLAGKRSFILSWEERLKISLDAAQGLEYLHNGCKPPIVHRDVKPTNIL 704 Query 742 LARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAM 795 L A K++D G+ I +L PE ++ Sbjct 705 LNEKLQA-------KMADFGLSRSFSVEGSGQISTVVAGSIGYLDPEYYST--RQMNEKS 755 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR--------------QHRLPEPSCP-- 839 D + G LLE+ P + S +EK H RL E Sbjct 756 DVYSLGVVLLEVITG--QPAIASSKTEKVHISDHVRSILANGDIRGIVDQRLRERYDVGS 813 Query 840 --QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 +++ + C + QRP+ ++ +L ++ + D + + Sbjct 814 AWKMSEIALACTEHTSAQRPTMSQVVMELKQIVYGIVTDQENYDDSTKM 862 >sp|Q9M0G5|CRK46_ARATH Cysteine-rich receptor-like protein kinase 46 OS=Arabidopsis thaliana OX=3702 GN=CRK46 PE=3 SV=1 Length=625 Score = 232 bits (591), Expect = 1e-63, Method: Composition-based stats. Identities = 69/316 (22%), Positives = 123/316 (39%), Gaps = 18/316 (6%) Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE 925 R++ + + + S + LG G +G+V G Sbjct 300 HLRIEKESESICTESHLMSFEYSTLKKATNNFNESCKLGVGGYGEVFKGTL-----SDGR 354 Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 +A+K L G + R EID++ H+++++ GCC +V E++ S Sbjct 355 EIAIKRLHV-SGKKPRDEIHNEIDVISRCQHKNLVRLLGCCFTNMNS--FIVYEFLANTS 411 Query 986 LRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA-QHYIHRDLAARNVLLDNDRLVKIG 1040 L L + + + EG+ YLH IHRD+ A N+LLD KI Sbjct 412 LDHILFNPEKKKELDWKKRRTIILGTAEGLEYLHETCKIIHRDIKASNILLDLKYKPKIS 471 Query 1041 DFGLAKAVPEGHE----YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 DFGLAK PEG + + + APE + + + D +SFGV + E+ + Sbjct 472 DFGLAKFYPEGGKDIPASSLSPSSIAGTLGYMAPEYISKGRLSNKIDAYSFGVLVLEITS 531 Query 1097 HCDSSQSPPTKFLE-LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155 +++ LE L+ ++ E++++ + V + C + Sbjct 532 GFRNNKFRSDNSLETLVTQVWKCFASNKMEEMIDKDMGEDTDKQEMKRVMQIGLLCTQES 591 Query 1156 ASFRPTFENLIPILKT 1171 RPT +I ++ + Sbjct 592 PQLRPTMSKVIQMVSS 607 Score = 204 bits (518), Expect = 4e-54, Method: Composition-based stats. Identities = 54/325 (17%), Positives = 100/325 (31%), Gaps = 65/325 (20%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 L + S + + LG G V++G L Sbjct 314 SHLMSFEYSTLKKATNNFNESCKLGVGGYGEVFKGTLSDGR------------------- 354 Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 + +K L S + ++S+ H +L + G C + +V E++ Sbjct 355 ------EIAIKRLHVSGKKPRDEIHNEIDVISRCQHKNLVRLLGCCFTNMNSFIVYEFLA 408 Query 692 HGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK-NLVHGNVCGRNILLARLGLA 748 + LD L + W + + A L YL ++H ++ NILL Sbjct 409 NTSLDHILFNPEKKKELDWKKRRTIILGTAEGLEYLHETCKIIHRDIKASNILLD----- 463 Query 749 EGTSPFIKLSDPGVGL-----------GALSREERVERIPWLAPECLPGGANSLSTAMDK 797 K+SD G+ +LS + ++APE + G LS +D Sbjct 464 --LKYKPKISDFGLAKFYPEGGKDIPASSLSPSSIAGTLGYMAPEYISKG--RLSNKIDA 519 Query 798 WGFGATLLEI-----------------CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840 + FG +LEI + + E+ + + Sbjct 520 YSFGVLVLEITSGFRNNKFRSDNSLETLVTQVWKCFASNKMEEMIDKDMGEDTDKQEMKR 579 Query 841 LATLTSQCLTYEPTQRPSFRTILRD 865 + + C P RP+ +++ Sbjct 580 VMQIGLLCTQESPQLRPTMSKVIQM 604 >sp|Q55EI8|Y9956_DICDI Probable serine/threonine-protein kinase DDB_G0268876 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0268876 PE=3 SV=1 Length=1385 Score = 241 bits (615), Expect = 1e-63, Method: Composition-based stats. Identities = 79/281 (28%), Positives = 128/281 (46%), Gaps = 31/281 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 ++G G G V + G +AVK + + E I+ L H++I+ Sbjct 763 EIGRGVSGVVKRGKWK------GYEIAVKQFNEEELGFSEREFHSEATIMSVLRHDNIVH 816 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHY 1019 G G+ + LV +Y GSL + + + A+++ A Q+ +GM YLH+ Sbjct 817 CVGGSAQPGK--MYLVCDYYSRGSLYSVITANICPLSNARIVHLALQVAKGMNYLHSLGI 874 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 IHRDL N+L+D D ++I DFGL++ V R+ + +P + A E LK + Sbjct 875 IHRDLKPGNLLIDQDWNIRISDFGLSRVVDN-----RMTKTVGTPC-YMAVEVLKGLTDY 928 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 +DV+SF L+E ++ Q P F ++ I+ +LE R P PD Sbjct 929 SQQADVYSFAFVLWECISR----QIPYKDFAQIQWISM----------VLEDSFRPPIPD 974 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 C E L+ CW + RP+F+ +I L+ + K Q Q Sbjct 975 SCLPEFRDLITMCWTSNPDDRPSFQQIITYLENLRLKMQDQ 1015 Score = 202 bits (515), Expect = 2e-51, Method: Composition-based stats. Identities = 54/305 (18%), Positives = 110/305 (36%), Gaps = 40/305 (13%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 + Q ++ +G+G V G+ + + Sbjct 750 LKYISQSDLELTKEIGRGVSGVVKRGKWKG--------------------------YEIA 783 Query 641 LKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +K + F+ A++MS + H ++ G + + +V +Y G L + Sbjct 784 VKQFNEEELGFSEREFHSEATIMSVLRHDNIVHCVGGSAQPGKMYLVCDYYSRGSLYSVI 843 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + A + +A Q+A ++YL + ++H ++ N+L+ + I++SD Sbjct 844 TANICPLSNARIVHLALQVAKGMNYLHSLGIIHRDLKPGNLLIDQ-------DWNIRISD 896 Query 760 PGVGLGALSR-EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 G+ +R + V ++A E L G S D + F L E + P + Sbjct 897 FGLSRVVDNRMTKTVGTPCYMAVEVLK-GLTDYSQQADVYSFAFVLWECISR-QIPYKDF 954 Query 819 SPSEKEHF---YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + + + +P+ P+ L + C T P RPSF+ I+ L L+ Sbjct 955 AQIQWISMVLEDSFRPPIPDSCLPEFRDLITMCWTSNPDDRPSFQQIITYLENLRLKMQD 1014 Query 876 DVLTV 880 + Sbjct 1015 QGIYQ 1019 >sp|Q9LFG1|Y3359_ARATH Putative leucine-rich repeat receptor-like serine/threonine-protein kinase At3g53590 OS=Arabidopsis thaliana OX=3702 GN=At3g53590 PE=1 SV=2 Length=937 Score = 238 bits (607), Expect = 1e-63, Method: Composition-based stats. Identities = 77/293 (26%), Positives = 121/293 (41%), Gaps = 25/293 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G +GKV VA+K + Q + EID+L L+H +++ Sbjct 620 IGRGSYGKVYKGIL-----SNKTEVAIKR-GEETSLQSEKEFLNEIDLLSRLHHRNLVSL 673 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLH---A 1016 G D GE+ LV EY+P G++RD+L + ++ + A +G+ YLH Sbjct 674 IGYSSDIGEQ--MLVYEYMPNGNVRDWLSANAADTLSFSMRSHVALGSAKGILYLHTEAN 731 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE----GHEYYRVREDGDSPVFWYAPEC 1072 IHRD+ N+LLD K+ DFGL++ P E V + PE Sbjct 732 PPVIHRDIKTSNILLDCQLHAKVADFGLSRLAPAFGEGDGEPAHVSTVVRGTPGYLDPEY 791 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + SDV+SFGV L ELLT P + +I + + + + Sbjct 792 FMTQQLTVRSDVYSFGVVLLELLTGM----HPFFEGTHIIREVRTANECGTVLSVADSRM 847 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 PDK ++ L C E RP ++ L+ + + + P +FS Sbjct 848 GQCSPDKV-KKLAELALWCCEDRPETRPPMSKVVKELEGICQSVR--EPEMFS 897 Score = 202 bits (514), Expect = 5e-52, Method: Composition-based stats. Identities = 67/385 (17%), Positives = 119/385 (31%), Gaps = 65/385 (17%) Query 553 PQPGETSNLIIMRGARASPRTL-NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLR 609 + + L R R R + + + SF + + +G+G+ VY+G L Sbjct 575 KRRENSHTLTKKRVFRTISREIKGVKKFSFVELSDATNGFDSSTLIGRGSYGKVYKGIL- 633 Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTH 669 + V +K + + F L+S++ H + Sbjct 634 ------------------------SNKTEVAIKRGEETSLQSEKEFLNEIDLLSRLHHRN 669 Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLE-- 726 L + G E ++V EY+ +G + WL + + + VA A + YL Sbjct 670 LVSLIGYSSDIGEQMLVYEYMPNGNVRDWLSANAADTLSFSMRSHVALGSAKGILYLHTE 729 Query 727 -NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS-----------REERVE 774 N ++H ++ NILL K++D G+ A + Sbjct 730 ANPPVIHRDIKTSNILLD-------CQLHAKVADFGLSRLAPAFGEGDGEPAHVSTVVRG 782 Query 775 RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP--SEKEHFYQ---- 828 +L PE L+ D + FG LLE+ G P + E + Sbjct 783 TPGYLDPEYFMT--QQLTVRSDVYSFGVVLLELL-TGMHPFFEGTHIIREVRTANECGTV 839 Query 829 ------RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 R + +LA L C P RP ++++L + + Sbjct 840 LSVADSRMGQCSPDKVKKLAELALWCCEDRPETRPPMSKVVKELEGICQSVREPEMFSET 899 Query 883 DSPASDPTVFHKRYLKKIRDLGEGH 907 T + L G Sbjct 900 TKLLCSKTSPSSSSVPSPLSLLPGS 924 >sp|Q9LSL5|LRK92_ARATH L-type lectin-domain containing receptor kinase IX.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK92 PE=1 SV=1 Length=675 Score = 233 bits (594), Expect = 1e-63, Method: Composition-based stats. Identities = 80/326 (25%), Positives = 127/326 (39%), Gaps = 24/326 (7%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 R + RD+ + N P + V R LGEG FG V Sbjct 307 WSRKQRKKKERDIENMISINKDLEREAGPRKFSYKDLVSATNRFSSHRKLGEGGFGAVYE 366 Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 N MVAVK L D Q ++ + E+ I+ L H ++++ G C ++ E Sbjct 367 GNLKEIN----TMVAVKKLSGD-SRQGKNEFLNEVKIISKLRHRNLVQLIGWCNEKNE-- 419 Query 974 LQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAAR 1027 L+ E VP GSL +L + + + YLH Q +HRD+ A Sbjct 420 FLLIYELVPNGSLNSHLFGKRPNLLSWDIRYKIGLGLASALLYLHEEWDQCVLHRDIKAS 479 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 N++LD++ VK+GDFGLA+ + HE + APE + + SD++SF Sbjct 480 NIMLDSEFNVKLGDFGLARLM--NHELGSHTTGLAGTFGYMAPEYVMKGSASKESDIYSF 537 Query 1088 GVTLYELLTHC--------DSSQSPPTKFLELIGIAQGQMTVLRL-TELLERGERLPRPD 1138 G+ L E++T D+S + L+ L T ++ Sbjct 538 GIVLLEIVTGRKSLERTQEDNSDTESDDEKSLVEKVWELYGKQELITSCVDDKLGEDFDK 597 Query 1139 KCPCEVYHLMKNCWETEASFRPTFEN 1164 K + L C + + RP+ + Sbjct 598 KEAECLLVLGLWCAHPDKNSRPSIKQ 623 Score = 228 bits (582), Expect = 5e-62, Method: Composition-based stats. Identities = 58/289 (20%), Positives = 102/289 (35%), Gaps = 48/289 (17%) Query 537 LLRAGDDCFSLRRCCLPQPGETSNLIIMRGA---RASPRTLNLSQLSFHRVDQKEITQLS 593 + R+ + + N+I + A PR + L + Sbjct 298 FMVITTVVVWSRKQRKKKERDIENMISINKDLEREAGPRKFSYKDLVS---ATNRFSSHR 354 Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LG+G VYEG L+ + V +K L Sbjct 355 KLGEGGFGAVYEGNLKEINTM------------------------VAVKKLSGDSRQGKN 390 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKM 712 F ++S++ H +L + G C E +++ E V +G L+ L +R + + + Sbjct 391 EFLNEVKIISKLRHRNLVQLIGWCNEKNEFLLIYELVPNGSLNSHLFGKRPNLLSWDIRY 450 Query 713 VVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----- 764 + LASAL YL + ++H ++ NI+L + +KL D G+ Sbjct 451 KIGLGLASALLYLHEEWDQCVLHRDIKASNIMLD-------SEFNVKLGDFGLARLMNHE 503 Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 ++APE + G+ S D + FG LLEI ++ Sbjct 504 LGSHTTGLAGTFGYMAPEYVMKGSA--SKESDIYSFGIVLLEIVTGRKS 550 >sp|Q9FLW0|Y5241_ARATH Probable receptor-like protein kinase At5g24010 OS=Arabidopsis thaliana OX=3702 GN=At5g24010 PE=1 SV=1 Length=824 Score = 236 bits (602), Expect = 1e-63, Method: Composition-based stats. Identities = 76/285 (27%), Positives = 122/285 (43%), Gaps = 20/285 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V VAVK + Q + EI IL + H H++ Sbjct 495 IGVGGFGMVFRGSLK-----DNTKVAVKR-GSPGSRQGLPEFLSEITILSKIRHRHLVSL 548 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLH---A 1016 G CE+Q E + LV EY+ G L+ +L + Q L G+ YLH + Sbjct 549 VGYCEEQSE--MILVYEYMDKGPLKSHLYGSTNPPLSWKQRLEVCIGAARGLHYLHTGSS 606 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 Q IHRD+ + N+LLDN+ + K+ DFGL+++ P E + V + PE + Sbjct 607 QGIIHRDIKSTNILLDNNYVAKVADFGLSRSGPCIDETH-VSTGVKGSFGYLDPEYFRRQ 665 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR---LTELLERGER 1133 + SDV+SFGV L+E+L C P E + +A+ + R L ++++ Sbjct 666 QLTDKSDVYSFGVVLFEVL--CARPAVDPLLVREQVNLAEWAIEWQRKGMLDQIVDPNIA 723 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 + + C RPT +++ L+ V + + Sbjct 724 DEIKPCSLKKFAETAEKCCADYGVDRPTIGDVLWNLEHVLQLQES 768 Score = 220 bits (560), Expect = 3e-58, Method: Composition-based stats. Identities = 66/335 (20%), Positives = 113/335 (34%), Gaps = 64/335 (19%) Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASP------RTLNLSQLSFHRVD-------QKEI 589 C R+ + E++ +R R S RT++ S R+ Sbjct 430 LCLCRRKNNKTRSSESTGWTPLRRFRGSSNSRTTERTVSSSGYHTLRISFAELQSGTNNF 489 Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 + +G G V+ G L+ +V +K P Sbjct 490 DRSLVIGVGGFGMVFRGSLKDN-------------------------TKVAVKRGSPGSR 524 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPM 708 F +++S++ H HL + G C E I+V EY++ GPL L + Sbjct 525 QGLPEFLSEITILSKIRHRHLVSLVGYCEEQSEMILVYEYMDKGPLKSHLYGSTNPPLSW 584 Query 709 AWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL- 764 ++ V A L YL ++ ++H ++ NILL + K++D G+ Sbjct 585 KQRLEVCIGAARGLHYLHTGSSQGIIHRDIKSTNILLDN-------NYVAKVADFGLSRS 637 Query 765 GALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 G E V +L PE L+ D + FG L E+ + Sbjct 638 GPCIDETHVSTGVKGSFGYLDPEYFR--RQQLTDKSDVYSFGVVLFEVLC-ARPAVDPLL 694 Query 820 PSEKEHF------YQRQHRLPEPSCPQLATLTSQC 848 E+ + +QR+ L + P +A C Sbjct 695 VREQVNLAEWAIEWQRKGMLDQIVDPNIADEIKPC 729 >sp|Q54R82|MKKA_DICDI Mitogen-activated protein kinase kinase kinase A OS=Dictyostelium discoideum OX=44689 GN=mkkA PE=1 SV=2 Length=942 Score = 238 bits (606), Expect = 1e-63, Method: Composition-based stats. Identities = 76/301 (25%), Positives = 136/301 (45%), Gaps = 29/301 (10%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL- 932 + + H +K + LG G +G V L N TGE+ AVK L Sbjct 147 QHTDFPSLIINEHEELISNHNIKWQKGQILGRGGYGSVYLG----LNKDTGELFAVKQLE 202 Query 933 --KADCGPQHRS---GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 + P+ ++ + +EI+++R+L H++I++Y G DQ S+ L EY+P GS+ Sbjct 203 IVDINSDPKLKNMILSFSKEIEVMRSLRHDNIVRYLGTSLDQSFLSVFL--EYIPGGSIS 260 Query 988 DYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 L + + ++ +QI +G+++LHA IHRD+ N+L+D +VK+ DFG +K Sbjct 261 SLLGKFGAFSENVIKVYTKQILQGLSFLHANSIIHRDIKGANILIDTKGIVKLSDFGCSK 320 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 + ++ + +W APE +K+ +SD+WS G + E+ T +Q P + Sbjct 321 SFSGIVSQFKSMQ---GTPYWMAPEVIKQTGHGRSSDIWSLGCVIVEMAT----AQPPWS 373 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 EL + + + P E + + C++ + RP L+ Sbjct 374 NITELAAVMYHIASSNSIPN---------IPSHMSQEAFDFLNLCFKRDPKERPDANQLL 424 Query 1167 P 1167 Sbjct 425 K 425 Score = 190 bits (482), Expect = 5e-48, Method: Composition-based stats. Identities = 55/307 (18%), Positives = 107/307 (35%), Gaps = 53/307 (17%) Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 +S H + + + LG+G +VY G + G Sbjct 163 ISNHNIKWQ---KGQILGRGGYGSVYLGLNKDTGELF----------------------- 196 Query 639 VVLKVL-------DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +K L DP ++ L+F + +M + H ++ G + + EY+ Sbjct 197 -AVKQLEIVDINSDPKLKNMILSFSKEIEVMRSLRHDNIVRYLGTSLDQSFLSVFLEYIP 255 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G + L + G V +Q+ LS+L +++H ++ G NIL+ G+ Sbjct 256 GGSISSLL-GKFGAFSENVIKVYTKQILQGLSFLHANSIIHRDIKGANILIDTKGI---- 310 Query 752 SPFIKLSDPGVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +KLSD G + W+APE + + S D W G ++E+ Sbjct 311 ---VKLSDFGCSKSFSGIVSQFKSMQGTPYWMAPEVIKQTGHGRS--SDIWSLGCVIVEM 365 Query 808 CFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 + P + + ++ +P + + C +P +RP +L Sbjct 366 A-TAQPPWSNITELAAVMYHIASSNSIPNIPSHMSQEAFDFLNLCFKRDPKERPDANQLL 424 Query 864 RDLTRLQ 870 + + Sbjct 425 KHPFIMN 431 >sp|Q9STV4|CIPK8_ARATH CBL-interacting serine/threonine-protein kinase 8 OS=Arabidopsis thaliana OX=3702 GN=CIPK8 PE=1 SV=1 Length=445 Score = 226 bits (577), Expect = 1e-63, Method: Composition-based stats. Identities = 63/268 (24%), Positives = 111/268 (41%), Gaps = 29/268 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959 +GEG F KV N TGE VA+K + + + K+EI I++ + H + Sbjct 14 TIGEGTFAKVKF----AQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLVRHPCV 69 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ + + + +++EY+ G L D + R+ + ++ + Q+ +G+ Y H++ Sbjct 70 VRLYEVLASRTK--IYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDYCHSKG 127 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N+LLD+ +KI DFGL+ +G + + APE L + Sbjct 128 VYHRDLKPENLLLDSQGNLKISDFGLSALPEQGVTILKTT---CGTPNYVAPEVLSHKGY 184 Query 1079 YYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 A D+WS GV LY L+ +M + L +++ E P Sbjct 185 NGAVADIWSCGVILYVLMAGYLPFD---------------EMDLPTLYSKIDKAE-FSCP 228 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165 L+ + R T + Sbjct 229 SYFALGAKSLINRILDPNPETRITIAEI 256 Score = 175 bits (443), Expect = 7e-46, Method: Composition-based stats. Identities = 53/321 (17%), Positives = 101/321 (31%), Gaps = 42/321 (13%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + +G+GT V ++ V +K++D S Sbjct 8 KYELGRTIGEGTFAKV------------------------KFAQNTETGESVAMKIVDRS 43 Query 648 ---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + S+M V H + ++ V + ++ EY+ G L + R G Sbjct 44 TIIKRKMVDQIKREISIMKLVRHPCVVRLYEVLASRTKIYIILEYITGGELFDKIVRN-G 102 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763 + + QL + Y +K + H ++ N+LL G +K+SD G+ Sbjct 103 RLSESEARKYFHQLIDGVDYCHSKGVYHRDLKPENLLLDSQG-------NLKISDFGLSA 155 Query 764 ---LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS- 819 G + ++APE L + D W G L + G P Sbjct 156 LPEQGVTILKTTCGTPNYVAPEVLSHKGYN-GAVADIWSCGVILYVLMA-GYLPFDEMDL 213 Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 P+ + + P +L ++ L P R + I +D L+ + ++ Sbjct 214 PTLYSKIDKAEFSCPSYFALGAKSLINRILDPNPETRITIAEIRKDEWFLKDYTPVQLID 273 Query 880 VNPDSPASDPTVFHKRYLKKI 900 + F + Sbjct 274 YEHVNLDDVYAAFDDPEEQTY 294 >sp|Q10SC8|CIPK9_ORYSJ CBL-interacting protein kinase 9 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK9 PE=2 SV=1 Length=456 Score = 227 bits (578), Expect = 1e-63, Method: Composition-based stats. Identities = 62/270 (23%), Positives = 118/270 (44%), Gaps = 27/270 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959 +GEG F KV + + TG+ +A+K L + +H+ K+EI ++ + H ++ Sbjct 32 TIGEGSFAKVKV----ARDTRTGDTLAIKVLDRNHVLRHKMVEQIKREISTMKLIKHPNV 87 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ + + + +V+EYV G L D + +G + + Q+ + Y H++ Sbjct 88 VQLHEVMASKSK--IYMVLEYVDGGELFDKIVNSGRLGEDEARRYFHQLINAVDYCHSRG 145 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N+LLD+ +K+ DFGL+ P+ E + +P + APE L + + Sbjct 146 VYHRDLKPENLLLDSHGALKVSDFGLSAFAPQTKEDGLLHTACGTPN-YVAPEVLADKGY 204 Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 A+DVWS G+ L+ L+ P ++ L +L+ + ++ P Sbjct 205 DGMAADVWSCGIILFVLMAGYLPFDDP---------------NLMTLYKLICKA-KVSCP 248 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 +K + R T ++ Sbjct 249 HWFSSGAKKFIKRILDPNPCTRITIAQILE 278 Score = 175 bits (444), Expect = 7e-46, Method: Composition-based stats. Identities = 59/305 (19%), Positives = 97/305 (32%), Gaps = 46/305 (15%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 RV + E+ +G+G+ V RD + Sbjct 21 TTRVGRYEL--GKTIGEGSFAKV------------------------KVARDTRTGDTLA 54 Query 641 LKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +KVLD +H H + S M + H ++ +H V + MV EYV+ G L Sbjct 55 IKVLDRNHVLRHKMVEQIKREISTMKLIKHPNVVQLHEVMASKSKIYMVLEYVDGGELFD 114 Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + G + QL +A+ Y ++ + H ++ N+LL G +K+ Sbjct 115 KI-VNSGRLGEDEARRYFHQLINAVDYCHSRGVYHRDLKPENLLLDSHGA-------LKV 166 Query 758 SDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 SD G+ A + ++APE L A D W G L + G Sbjct 167 SDFGLSAFAPQTKEDGLLHTACGTPNYVAPEVLADKGYD-GMAADVWSCGIIL-FVLMAG 224 Query 812 EAPLQSRSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P + + P + L P R + IL D + Sbjct 225 YLPFDDPNLMTLYKLICKAKVSCPHWFSSGAKKFIKRILDPNPCTRITIAQILEDDWFKK 284 Query 871 PHNLA 875 + Sbjct 285 DYKPP 289 >sp|Q6ZLP5|CIPKN_ORYSJ CBL-interacting protein kinase 23 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK23 PE=2 SV=1 Length=450 Score = 226 bits (577), Expect = 1e-63, Method: Composition-based stats. Identities = 67/270 (25%), Positives = 113/270 (42%), Gaps = 27/270 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959 LGEG F KV N +GE VA+K L D +H+ + K+EI ++ + H ++ Sbjct 18 TLGEGTFAKVKF----ARNADSGENVAIKILDKDKVLKHKMIAQIKREISTMKLIRHPNV 73 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I+ + + + +VME V G L D + R + + QQ+ + Y H++ Sbjct 74 IRMHEVMASKTK--IYIVMELVTGGELFDKIASRGRLKEDDARKYFQQLINAVDYCHSRG 131 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N+LLD +K+ DFGL+ + E + +P + APE + + Sbjct 132 VYHRDLKPENLLLDASGTLKVSDFGLSALSQQVREDGLLHTTCGTPN-YVAPEVINNKGY 190 Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 +D+WS GV L+ L+ + ++ L + + + + P Sbjct 191 DGAKADLWSCGVILFVLMAGYLPFED---------------SNLMSLYKKIFKAD-FSCP 234 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L+K + S R T LI Sbjct 235 SWFSTSAKKLIKKILDPNPSTRITIAELIN 264 Score = 176 bits (446), Expect = 4e-46, Method: Composition-based stats. Identities = 58/304 (19%), Positives = 98/304 (32%), Gaps = 44/304 (14%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 RV + E+ LG+GT V R G V +K Sbjct 9 RVGRYEL--GRTLGEGTFAKVKFARNADSGEN------------------------VAIK 42 Query 643 VLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +LD H + S M + H ++ +H V + +V E V G L + Sbjct 43 ILDKDKVLKHKMIAQIKREISTMKLIRHPNVIRMHEVMASKTKIYIVMELVTGGELFDKI 102 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 RG + QQL +A+ Y ++ + H ++ N+LL S +K+SD Sbjct 103 -ASRGRLKEDDARKYFQQLINAVDYCHSRGVYHRDLKPENLLLD-------ASGTLKVSD 154 Query 760 PGV-GLGALSRE-----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ L RE ++APE + D W G L + Sbjct 155 FGLSALSQQVREDGLLHTTCGTPNYVAPEVINNKGYD-GAKADLWSCGVILFVLMAGYLP 213 Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 S S + ++ P L + L P+ R + ++ + + + Sbjct 214 FEDSNLMSLYKKIFKADFSCPSWFSTSAKKLIKKILDPNPSTRITIAELINNEWFKKGYQ 273 Query 874 LADV 877 Sbjct 274 PPRF 277 >sp|Q9LJF3|BRL3_ARATH Receptor-like protein kinase BRI1-like 3 OS=Arabidopsis thaliana OX=3702 GN=BRL3 PE=1 SV=1 Length=1164 Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats. Identities = 71/283 (25%), Positives = 119/283 (42%), Gaps = 20/283 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V G +VA+K L G R + E++ + + H +++ Sbjct 864 IGSGGFGDVYKA-----KLADGSVVAIKKLIQVTGQGDRE-FMAEMETIGKIKHRNLVPL 917 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYLHA 1016 G C+ E+ LV EY+ GSL L + + + A G+A+LH Sbjct 918 LGYCKIGEER--LLVYEYMKYGSLETVLHEKTKKGGIFLDWSARKKIAIGAARGLAFLHH 975 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 H IHRD+ + NVLLD D + ++ DFG+A+ V + V +P + PE Sbjct 976 SCIPHIIHRDMKSSNVLLDQDFVARVSDFGMARLVSALDTHLSVSTLAGTP-GYVPPEYY 1034 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT-KFLELIGIAQGQMTVLRLTELLERGE 1132 + ++ DV+S+GV L ELL+ + L+G A+ R E+L+ Sbjct 1035 QSFRCTAKGDVYSYGVILLELLSGKKPIDPEEFGEDNNLVGWAKQLYREKRGAEILDPEL 1094 Query 1133 RLPRP-DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + D + C + RPT ++ + K + + Sbjct 1095 VTDKSGDVELLHYLKIASQCLDDRPFKRPTMIQVMTMFKELVQ 1137 Score = 212 bits (539), Expect = 1e-54, Method: Composition-based stats. Identities = 63/330 (19%), Positives = 119/330 (36%), Gaps = 69/330 (21%) Query 576 LSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L +L+F + + S +G G +VY+ +L Sbjct 843 LRKLTFAHLLEATNGFSADSMIGSGGFGDVYKAKLADGS--------------------- 881 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 V +K L F + ++ H +L + G C G E ++V EY+++G Sbjct 882 ----VVAIKKLIQVTGQGDREFMAEMETIGKIKHRNLVPLLGYCKIGEERLLVYEYMKYG 937 Query 694 PLDVWLRRERGH----VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLG 746 L+ L + + + + +A A L++L + +++H ++ N+LL + Sbjct 938 SLETVLHEKTKKGGIFLDWSARKKIAIGAARGLAFLHHSCIPHIIHRDMKSSNVLLDQDF 997 Query 747 LAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800 +A ++SD G+ LS ++ PE + + D + + Sbjct 998 VA-------RVSDFGMARLVSALDTHLSVSTLAGTPGYVPPEYYQ--SFRCTAKGDVYSY 1048 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFY------QRQHRLPEPSCPQLAT----------- 843 G LLE+ G+ P+ E + R+ R E P+L T Sbjct 1049 GVILLELLS-GKKPIDPEEFGEDNNLVGWAKQLYREKRGAEILDPELVTDKSGDVELLHY 1107 Query 844 --LTSQCLTYEPTQRPSFRTILRDLTRLQP 871 + SQCL P +RP+ ++ L Sbjct 1108 LKIASQCLDDRPFKRPTMIQVMTMFKELVQ 1137 >sp|Q8L899|BRI1_SOLPE Systemin receptor SR160 OS=Solanum peruvianum OX=4082 PE=1 SV=1 Length=1207 Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats. Identities = 74/292 (25%), Positives = 122/292 (42%), Gaps = 30/292 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +G G FG V G +VA+K L G R + E++ + + H Sbjct 888 FHNDSLVGSGGFGDVYKAQLK-----DGSVVAIKKLIHVSGQGDRE-FTAEMETIGKIKH 941 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGM 1011 +++ G C+ E+ LV EY+ GSL D L + A G+ Sbjct 942 RNLVPLLGYCKVGEER--LLVYEYMKYGSLEDVLHDRKKTGIKLNWPARRKIAIGAARGL 999 Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 A+LH H IHRD+ + NVLLD + ++ DFG+A+ + + V +P + Sbjct 1000 AFLHHNCIPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTP-GYV 1058 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI----AQGQMTVLRL 1124 PE + ++ DV+S+GV L ELLT + S L+G A+G++T + Sbjct 1059 PPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFGDNNLVGWVKLHAKGKITDVFD 1118 Query 1125 TELLERGERLPRPDKCPCEVYH---LMKNCWETEASFRPTFENLIPILKTVH 1173 ELL+ + E+ + C + RPT ++ + K + Sbjct 1119 RELLKEDASIEI------ELLQHLKVACACLDDRHWKRPTMIQVMAMFKEIQ 1164 Score = 206 bits (523), Expect = 1e-52, Method: Composition-based stats. Identities = 49/253 (19%), Positives = 93/253 (37%), Gaps = 49/253 (19%) Query 576 LSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L +L+F + S +G G +VY+ +L+ Sbjct 873 LRKLTFADLLEATNGFHNDSLVGSGGFGDVYKAQLKDGS--------------------- 911 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 V +K L F + ++ H +L + G C G E ++V EY+++G Sbjct 912 ----VVAIKKLIHVSGQGDREFTAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKYG 967 Query 694 PLDVWLRRERG---HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGL 747 L+ L + + + +A A L++L + +++H ++ N+LL Sbjct 968 SLEDVLHDRKKTGIKLNWPARRKIAIGAARGLAFLHHNCIPHIIHRDMKSSNVLLDE--- 1024 Query 748 AEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 + ++SD G+ LS ++ PE + ST D + +G Sbjct 1025 ----NLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQ--SFRCSTKGDVYSYG 1078 Query 802 ATLLEICFDGEAP 814 LLE+ G+ P Sbjct 1079 VVLLELL-TGKQP 1090 >sp|Q8GUQ5|BRI1_SOLLC Brassinosteroid LRR receptor kinase OS=Solanum lycopersicum OX=4081 GN=CURL3 PE=1 SV=1 Length=1207 Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats. Identities = 74/292 (25%), Positives = 122/292 (42%), Gaps = 30/292 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +G G FG V G +VA+K L G R + E++ + + H Sbjct 888 FHNDSLVGSGGFGDVYKAQLK-----DGSVVAIKKLIHVSGQGDRE-FTAEMETIGKIKH 941 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGM 1011 +++ G C+ E+ LV EY+ GSL D L + A G+ Sbjct 942 RNLVPLLGYCKVGEER--LLVYEYMKYGSLEDVLHDRKKIGIKLNWPARRKIAIGAARGL 999 Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 A+LH H IHRD+ + NVLLD + ++ DFG+A+ + + V +P + Sbjct 1000 AFLHHNCIPHIIHRDMKSSNVLLDENLEARVSDFGMARLMSAMDTHLSVSTLAGTP-GYV 1058 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI----AQGQMTVLRL 1124 PE + ++ DV+S+GV L ELLT + S L+G A+G++T + Sbjct 1059 PPEYYQSFRCSTKGDVYSYGVVLLELLTGKQPTDSADFGDNNLVGWVKLHAKGKITDVFD 1118 Query 1125 TELLERGERLPRPDKCPCEVYH---LMKNCWETEASFRPTFENLIPILKTVH 1173 ELL+ + E+ + C + RPT ++ + K + Sbjct 1119 RELLKEDASIEI------ELLQHLKVACACLDDRHWKRPTMIQVMAMFKEIQ 1164 Score = 206 bits (523), Expect = 1e-52, Method: Composition-based stats. Identities = 49/253 (19%), Positives = 93/253 (37%), Gaps = 49/253 (19%) Query 576 LSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L +L+F + S +G G +VY+ +L+ Sbjct 873 LRKLTFADLLEATNGFHNDSLVGSGGFGDVYKAQLKDGS--------------------- 911 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 V +K L F + ++ H +L + G C G E ++V EY+++G Sbjct 912 ----VVAIKKLIHVSGQGDREFTAEMETIGKIKHRNLVPLLGYCKVGEERLLVYEYMKYG 967 Query 694 PLDVWLRRERG---HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGL 747 L+ L + + + +A A L++L + +++H ++ N+LL Sbjct 968 SLEDVLHDRKKIGIKLNWPARRKIAIGAARGLAFLHHNCIPHIIHRDMKSSNVLLDE--- 1024 Query 748 AEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 + ++SD G+ LS ++ PE + ST D + +G Sbjct 1025 ----NLEARVSDFGMARLMSAMDTHLSVSTLAGTPGYVPPEYYQ--SFRCSTKGDVYSYG 1078 Query 802 ATLLEICFDGEAP 814 LLE+ G+ P Sbjct 1079 VVLLELL-TGKQP 1090 >sp|Q9ZPS9|BRL2_ARATH Serine/threonine-protein kinase BRI1-like 2 OS=Arabidopsis thaliana OX=3702 GN=BRL2 PE=1 SV=1 Length=1143 Score = 239 bits (611), Expect = 1e-63, Method: Composition-based stats. Identities = 65/296 (22%), Positives = 119/296 (40%), Gaps = 34/296 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG+V G VA+K L Q + E++ L + H +++ Sbjct 844 IGHGGFGEVFKATLK-----DGSSVAIKKL-IRLSCQGDREFMAEMETLGKIKHRNLVPL 897 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSIGLAQLLLFAQQICEGMAYLH 1015 G C+ E+ LV E++ GSL + L R +G + A+ +G+ +LH Sbjct 898 LGYCKIGEER--LLVYEFMQYGSLEEVLHGPRTGEKRRILGWEERKKIAKGAAKGLCFLH 955 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 H IHRD+ + NVLLD D ++ DFG+A+ + + V +P + PE Sbjct 956 HNCIPHIIHRDMKSSNVLLDQDMEARVSDFGMARLISALDTHLSVSTLAGTP-GYVPPEY 1014 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + ++ DV+S GV + E+L+ + L+G ++ + + E+++ Sbjct 1015 YQSFRCTAKGDVYSIGVVMLEILSGKRPTDKEEFGDTNLVGWSKMKAREGKHMEVIDEDL 1074 Query 1133 RLPRPDKCPCE---------------VYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + E + C + S RP ++ L+ + Sbjct 1075 LKEGSSESLNEKEGFEGGVIVKEMLRYLEIALRCVDDFPSKRPNMLQVVASLRELR 1130 Score = 199 bits (507), Expect = 8e-51, Method: Composition-based stats. Identities = 47/274 (17%), Positives = 94/274 (34%), Gaps = 51/274 (19%) Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L +L F ++ + S +G G V++ L+ S Sbjct 822 QLRKLKFSQLIEATNGFSAASMIGHGGFGEVFKATLKDGSS------------------- 862 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 V +K L F + ++ H +L + G C G E ++V E++++ Sbjct 863 ------VAIKKLIRLSCQGDREFMAEMETLGKIKHRNLVPLLGYCKIGEERLLVYEFMQY 916 Query 693 GPLDVWLRRERGH-----VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744 G L+ L R + + +A+ A L +L + +++H ++ N+LL + Sbjct 917 GSLEEVLHGPRTGEKRRILGWEERKKIAKGAAKGLCFLHHNCIPHIIHRDMKSSNVLLDQ 976 Query 745 LGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKW 798 ++SD G+ LS ++ PE + + D + Sbjct 977 -------DMEARVSDFGMARLISALDTHLSVSTLAGTPGYVPPEYYQ--SFRCTAKGDVY 1027 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832 G +LEI G+ P + + + Sbjct 1028 SIGVVMLEILS-GKRPTDKEEFGDTNLVGWSKMK 1060 >sp|Q94CG0|CIPKL_ARATH CBL-interacting serine/threonine-protein kinase 21 OS=Arabidopsis thaliana OX=3702 GN=CIPK21 PE=1 SV=1 Length=416 Score = 225 bits (574), Expect = 2e-63, Method: Composition-based stats. Identities = 76/268 (28%), Positives = 112/268 (42%), Gaps = 29/268 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHI 959 +GEG+F KV L YD TN G VAVK + Q S K+EI ++ L H +I Sbjct 17 TIGEGNFAKVKLG-YDTTN---GTYVAVKIIDKALVIQKGLESQVKREIRTMKLLNHPNI 72 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 ++ + + +VMEYV G L D L R + + QQ+ + + Y H + Sbjct 73 VQIHEVI--GTKTKICIVMEYVSGGQLSDRLGRQKMKESDARKLFQQLIDAVDYCHNRGV 130 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 HRDL +N+LLD+ +K+ DFGL+ G + + APE + + Sbjct 131 YHRDLKPQNLLLDSKGNLKVSDFGLSAVPKSGD----MLSTACGSPCYIAPELIMNKGYS 186 Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 A DVWS GV L+ELL T+ L + + R + P Sbjct 187 GAAVDVWSCGVILFELLAGYPPFDD---------------HTLPVLYKKILRAD-YTFPP 230 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLI 1166 E L+ N + R T +I Sbjct 231 GFTGEQKRLIFNILDPNPLSRITLAEII 258 Score = 174 bits (440), Expect = 1e-45, Method: Composition-based stats. Identities = 56/311 (18%), Positives = 103/311 (33%), Gaps = 44/311 (14%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 + ++ + EI +G+G V G D Sbjct 1 MGLFGTKKIGKYEI--GRTIGEGNFAKVKLGY------------------------DTTN 34 Query 636 ELRVVLKVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 V +K++D + + M ++H ++ +H V + +V EYV Sbjct 35 GTYVAVKIIDKALVIQKGLESQVKREIRTMKLLNHPNIVQIHEVIGTKTKICIVMEYVSG 94 Query 693 GPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752 G L L R++ + + + QQL A+ Y N+ + H ++ +N+LL G Sbjct 95 GQLSDRLGRQK--MKESDARKLFQQLIDAVDYCHNRGVYHRDLKPQNLLLDSKG------ 146 Query 753 PFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 +K+SD G+ ++APE + S A+D W G L E+ Sbjct 147 -NLKVSDFGLSAVPKSGDMLSTACGSPCYIAPELIMNKGYS-GAAVDVWSCGVILFELLA 204 Query 810 DGEAPLQSRS-PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 G P + P + + + P + L L P R + I+ + Sbjct 205 -GYPPFDDHTLPVLYKKILRADYTFPPGFTGEQKRLIFNILDPNPLSRITLAEIIIKDSW 263 Query 869 LQPHNLADVLT 879 + Sbjct 264 FKIGYTPVYHQ 274 >sp|O22187|Y2232_ARATH Probable receptor-like protein kinase At2g23200 OS=Arabidopsis thaliana OX=3702 GN=At2g23200 PE=3 SV=1 Length=834 Score = 236 bits (602), Expect = 2e-63, Method: Composition-based stats. Identities = 70/280 (25%), Positives = 119/280 (43%), Gaps = 18/280 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FG V G A+K K G Q ++ EI +L + H H++ Sbjct 494 IGKGGFGYVYKAIL-----PDGTKAAIKRGKTGSG-QGILEFQTEIQVLSRIRHRHLVSL 547 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHAQH- 1018 G CE+ E + LV E++ G+L+++L S+ Q L G+ YLH+ Sbjct 548 TGYCEENSE--MILVYEFMEKGTLKEHLYGSNLPSLTWKQRLEICIGAARGLDYLHSSGS 605 Query 1019 ---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 IHRD+ + N+LLD + K+ DFGL+K + + + + PE L+ Sbjct 606 EGAIIHRDVKSTNILLDEHNIAKVADFGLSKI--HNQDESNISINIKGTFGYLDPEYLQT 663 Query 1076 YKFYYASDVWSFGVTLYE-LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 +K SDV++FGV L E L P + + L + + E+L+ Sbjct 664 HKLTEKSDVYAFGVVLLEVLFARPAIDPYLPHEEVNLSEWVMFCKSKGTIDEILDPSLIG 723 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + + + C + RP+ ++I L+ V + Sbjct 724 QIETNSLKKFMEIAEKCLKEYGDERPSMRDVIWDLEYVLQ 763 Score = 225 bits (573), Expect = 7e-60, Method: Composition-based stats. Identities = 71/359 (20%), Positives = 121/359 (34%), Gaps = 64/359 (18%) Query 554 QPGETSNLIIMRGARASPRTLNLS---QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRV 610 + G + N I + + R L+L + + +G+G VY+ L Sbjct 450 RGGSSDNRPISQYHNSPLRNLHLGLTIPFTDILSATNNFDEQLLIGKGGFGYVYKAILPD 509 Query 611 EGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHL 670 + +K L F ++S++ H HL Sbjct 510 G-------------------------TKAAIKRGKTGSGQGILEFQTEIQVLSRIRHRHL 544 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKN 729 + G C E I+V E++E G L L + ++ + A L YL + Sbjct 545 VSLTGYCEENSEMILVYEFMEKGTLKEHLYGSNLPSLTWKQRLEICIGAARGLDYLHSSG 604 Query 730 ----LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLA 780 ++H +V NILL +A K++D G+ E + +L Sbjct 605 SEGAIIHRDVKSTNILLDEHNIA-------KVADFGLSKIHNQDESNISINIKGTFGYLD 657 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICF-----DGEAPLQSRSPSEKEHFYQRQHRLPE 835 PE L + L+ D + FG LLE+ F D P + + SE F + + + E Sbjct 658 PEYLQT--HKLTEKSDVYAFGVVLLEVLFARPAIDPYLPHEEVNLSEWVMFCKSKGTIDE 715 Query 836 PSCPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 P L + +CL +RPS R ++ DL + + Sbjct 716 ILDPSLIGQIETNSLKKFMEIAEKCLKEYGDERPSMRDVIWDLEYVLQLQMMTNRREAH 774 >sp|O49545|BAME1_ARATH Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM1 OS=Arabidopsis thaliana OX=3702 GN=BAM1 PE=1 SV=1 Length=1003 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 81/312 (26%), Positives = 128/312 (41%), Gaps = 17/312 (5%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 L+ + + + LK+ +G+G G V G++VA Sbjct 666 LKKASESRAWRLTAFQRLDFTCDDVLDSLKEDNIIGKGGAGIVYKGV-----MPNGDLVA 720 Query 929 VKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 VK L A G H G+ EI L + H HI++ G C + LV EY+P GSL Sbjct 721 VKRLAAMSRGSSHDHGFNAEIQTLGRIRHRHIVRLLGFCSNHETN--LLVYEYMPNGSLG 778 Query 988 DYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGD 1041 + L + A + +G+ YLH +HRD+ + N+LLD++ + D Sbjct 779 EVLHGKKGGHLHWDTRYKIALEAAKGLCYLHHDCSPLIVHRDVKSNNILLDSNFEAHVAD 838 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLAK + + + S + APE K SDV+SFGV L EL+T Sbjct 839 FGLAKFLQDSGTSECMSAIAGS-YGYIAPEYAYTLKVDEKSDVYSFGVVLLELVTGRKPV 897 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERL-PRPDKCPCEVYHLMKNCWETEASFRP 1160 ++++ + + + L RL P V+++ C E +A RP Sbjct 898 GE-FGDGVDIVQWVRKMTDSNKDSVLKVLDPRLSSIPIHEVTHVFYVAMLCVEEQAVERP 956 Query 1161 TFENLIPILKTV 1172 T ++ IL + Sbjct 957 TMREVVQILTEI 968 Score = 197 bits (500), Expect = 4e-50, Method: Composition-based stats. Identities = 57/323 (18%), Positives = 108/323 (33%), Gaps = 64/323 (20%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + + + +G+G VY+G + V +K L Sbjct 692 DSLKEDNIIGKGGAGIVYKGVMPNGD-------------------------LVAVKRLAA 726 Query 647 SHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER- 703 + F + ++ H H+ + G C N++V EY+ +G L L ++ Sbjct 727 MSRGSSHDHGFNAEIQTLGRIRHRHIVRLLGFCSNHETNLLVYEYMPNGSLGEVLHGKKG 786 Query 704 GHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 GH+ + +A + A L YL + +VH +V NILL ++ ++D Sbjct 787 GHLHWDTRYKIALEAAKGLCYLHHDCSPLIVHRDVKSNNILLD-------SNFEAHVADF 839 Query 761 GVGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ ++APE + D + FG LLE+ G P Sbjct 840 GLAKFLQDSGTSECMSAIAGSYGYIAPEYA--YTLKVDEKSDVYSFGVVLLELV-TGRKP 896 Query 815 -----------------LQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857 S S + R +P + + C+ + +RP Sbjct 897 VGEFGDGVDIVQWVRKMTDSNKDSVLKVLDPRLSSIPIHEVTHVFYVAMLCVEEQAVERP 956 Query 858 SFRTILRDLTRLQPHNLADVLTV 880 + R +++ LT + + + Sbjct 957 TMREVVQILTEIPKLPPSKDQPM 979 >sp|P51957|NEK4_HUMAN Serine/threonine-protein kinase Nek4 OS=Homo sapiens OX=9606 GN=NEK4 PE=1 SV=2 Length=841 Score = 236 bits (602), Expect = 2e-63, Method: Composition-based stats. Identities = 64/274 (23%), Positives = 116/274 (42%), Gaps = 27/274 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLY 955 +R +G+G +G+V+L + G+ +K L + + R +QE +L L Sbjct 6 YCYLRVVGKGSYGEVTLV----KHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLK 61 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMA 1012 H +I+ YK E G+ L +VM + G L L + Q++ + QI + Sbjct 62 HPNIVTYKESWE-GGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ 120 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 YLH +H +HRDL +NV L ++K+GD G+A+ + + + ++ +PE Sbjct 121 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVL---ENHCDMASTLIGTPYYMSPEL 177 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + Y SDVW+ G +YE+ T + + L + G+ Sbjct 178 FSNKPYNYKSDVWALGCCVYEMATLKHAF---------------NAKDMNSLVYRIIEGK 222 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 P P E+ L++ RP+ +++ Sbjct 223 LPPMPRDYSPELAELIRTMLSKRPEERPSVRSIL 256 Score = 176 bits (445), Expect = 8e-44, Method: Composition-based stats. Identities = 60/284 (21%), Positives = 105/284 (37%), Gaps = 38/284 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 L +G+G+ V LV R G++ + L + Sbjct 8 YLRVVGKGSYGEV----------------------TLVKHRRDGKQYVIKKLNLRNASSR 45 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHV-PM 708 A + A L+SQ+ H ++ G +V + E G L L+ ++G + P Sbjct 46 ERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPE 105 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + Q+A AL YL K+++H ++ +N+ L R + IK+ D G+ + Sbjct 106 NQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNI-------IKVGDLGIARVLEN 158 Query 769 R----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + +++PE + D W G + E+ A S Sbjct 159 HCDMASTLIGTPYYMSPELFSNKPYNY--KSDVWALGCCVYEMATLKHAFNAKDMNSLVY 216 Query 825 HFYQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + + +P P+LA L L+ P +RPS R+ILR Sbjct 217 RIIEGKLPPMPRDYSPELAELIRTMLSKRPEERPSVRSILRQPY 260 >sp|Q6UD73|LYK3_MEDTR LysM domain receptor-like kinase 3 OS=Medicago truncatula OX=3880 GN=LYK3 PE=1 SV=1 Length=620 Score = 231 bits (590), Expect = 2e-63, Method: Composition-based stats. Identities = 69/296 (23%), Positives = 119/296 (40%), Gaps = 28/296 (9%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G+G FG V GE A+K + S + E+ +L ++H ++ Sbjct 325 DNKIGQGGFGAVYYAELR------GEKTAIKKMDVQAS----SEFLCELKVLTHVHHLNL 374 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLHA 1016 ++ G C E SL LV E++ G+L YL + + + A G+ Y+H Sbjct 375 VRLIGYCV---EGSLFLVYEHIDNGNLGQYLHGIGTEPLPWSSRVQIALDSARGLEYIHE 431 Query 1017 QHY---IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRD+ + N+L+D + K+ DFGL K + G+ R + PE Sbjct 432 HTVPVYIHRDVKSANILIDKNLRGKVADFGLTKLIEVGNSTLHTR--LVGTFGYMPPEYA 489 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR-------LTE 1126 + DV++FGV LYEL+T ++ E G+ Q L L + Sbjct 490 QYGDVSPKIDVYAFGVVLYELITAKNAVLKTGESVAESKGLVQLFEEALHRMDPLEGLRK 549 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182 L++ + P ++ L + C RP+ +++ L T+ + Sbjct 550 LVDPRLKENYPIDSVLKMAQLGRACTRDNPLLRPSMRSIVVALMTLSSPTEDCDDD 605 Score = 189 bits (479), Expect = 4e-49, Method: Composition-based stats. Identities = 65/333 (20%), Positives = 116/333 (35%), Gaps = 71/333 (21%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + + +GQG VY LR E + +K + Sbjct 318 ATNNFSLDNKIGQGGFGAVYYAELRGEKT--------------------------AIKKM 351 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ER 703 D + F +++ V H +L + G CV G +V E++++G L +L Sbjct 352 D---VQASSEFLCELKVLTHVHHLNLVRLIGYCVEGS-LFLVYEHIDNGNLGQYLHGIGT 407 Query 704 GHVPMAWKMVVAQQLASALSYLENKNL---VHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 +P + ++ +A A L Y+ + +H +V NIL+ + + K++D Sbjct 408 EPLPWSSRVQIALDSARGLEYIHEHTVPVYIHRDVKSANILIDK-------NLRGKVADF 460 Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP- 814 G+ + V ++ PE G +S +D + FG L E+ A Sbjct 461 GLTKLIEVGNSTLHTRLVGTFGYMPPEYAQYG--DVSPKIDVYAFGVVLYELITAKNAVL 518 Query 815 LQSRSPSE----KEHFYQRQHRL------------------PEPSCPQLATLTSQCLTYE 852 S +E + F + HR+ P S ++A L C Sbjct 519 KTGESVAESKGLVQLFEEALHRMDPLEGLRKLVDPRLKENYPIDSVLKMAQLGRACTRDN 578 Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885 P RPS R+I+ L L + ++ Sbjct 579 PLLRPSMRSIVVALMTLSSPTEDCDDDSSYENQ 611 >sp|P48963|CDK2_MESAU Cyclin-dependent kinase 2 OS=Mesocricetus auratus OX=10036 GN=CDK2 PE=2 SV=1 Length=298 Score = 221 bits (563), Expect = 2e-63, Method: Composition-based stats. Identities = 68/289 (24%), Positives = 121/289 (42%), Gaps = 30/289 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ Sbjct 1 MENFQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICE 1009 L H +I+K E L LV E + L+ ++ I L + + Q+ + Sbjct 57 ELNHPNIVKLLDVI--HTENKLYLVFELLHQ-DLKKFMDASAVTGIPLPLIKSYLFQLLQ 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 G+A+ H+ +HRDL +N+L++ + +K+ DFGLA+A R +++ A Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVP---VRTYTHEVVTLWYRA 170 Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL- 1127 PE L K+Y A D+WS G E++T ++ +L I + T + Sbjct 171 PEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPG-DSEIDQLFRIFRTLGTPDEVVWPG 229 Query 1128 --LERGERLPRPDKCPCEV-----------YHLMKNCWETEASFRPTFE 1163 + P + L+ + + R + + Sbjct 230 VTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAK 278 Score = 169 bits (427), Expect = 3e-45, Method: Composition-based stats. Identities = 47/266 (18%), Positives = 94/266 (35%), Gaps = 40/266 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 + ++ +G+GT VY+ + ++ G V LK Sbjct 1 MENFQKVEKIGEGTYGVVYKAKNKLTGE------------------------VVALKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 LD + SL+ +++H ++ + V + +V E + H L ++ Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFELL-HQDLKKFMDASA 95 Query 704 -GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 +P+ QL L++ + ++H ++ +N+L+ G IKL+D G+ Sbjct 96 VTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEG-------SIKLADFGL 148 Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + + APE L G STA+D W G E+ Sbjct 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKY-YSTAVDIWSLGCIFAEMVTRRALFPGDS 207 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ E P + ++ Sbjct 208 EIDQLFRIFRTLGTPDEVVWPGVTSM 233 >sp|Q9SHI2|Y1723_ARATH Leucine-rich repeat receptor-like serine/threonine-protein kinase At1g17230 OS=Arabidopsis thaliana OX=3702 GN=At1g17230 PE=1 SV=2 Length=1101 Score = 239 bits (610), Expect = 2e-63, Method: Composition-based stats. Identities = 83/344 (24%), Positives = 126/344 (37%), Gaps = 28/344 (8%) Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899 L T C T + L ++ D V R + Sbjct 747 FLITFLGLCWTIK-----RREPAFVALEDQTKPDVMDSYYFPKKGFTYQGLVDATRNFSE 801 Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEH 958 LG G G V GE++AVK L + G + ++ EI L + H + Sbjct 802 DVVLGRGACGTVYKAEMSG-----GEVIAVKKLNSRGEGASSDNSFRAEISTLGKIRHRN 856 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYL 1014 I+K G C Q L+ EY+ GSL + L R + A EG+ YL Sbjct 857 IVKLYGFCYHQNSN--LLLYEYMSKGSLGEQLQRGEKNCLLDWNARYRIALGAAEGLCYL 914 Query 1015 HA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 H +HRD+ + N+LLD +GDFGLAK + Y + + APE Sbjct 915 HHDCRPQIVHRDIKSNNILLDERFQAHVGDFGLAKLID--LSYSKSMSAVAGSYGYIAPE 972 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 K D++SFGV L EL+T Q P + +L+ + + + + + Sbjct 973 YAYTMKVTEKCDIYSFGVVLLELITGKPPVQ-PLEQGGDLVNWVRRSIRNM-IPTIEMFD 1030 Query 1132 ERLPRPDKCPCE----VYHLMKNCWETEASFRPTFENLIPILKT 1171 RL DK V + C + RPT ++ ++ Sbjct 1031 ARLDTNDKRTVHEMSLVLKIALFCTSNSPASRPTMREVVAMITE 1074 Score = 189 bits (481), Expect = 1e-47, Method: Composition-based stats. Identities = 49/272 (18%), Positives = 92/272 (34%), Gaps = 49/272 (18%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + ++ LG+G VY+ + + +K L Sbjct 795 ATRNFSEDVVLGRGACGTVYKAEMSGGE-------------------------VIAVKKL 829 Query 645 DPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 + + F S + ++ H ++ ++G C N+++ EY+ G L L+R Sbjct 830 NSRGEGASSDNSFRAEISTLGKIRHRNIVKLYGFCYHQNSNLLLYEYMSKGSLGEQLQRG 889 Query 703 RGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + + W + +A A L YL + +VH ++ NILL A + Sbjct 890 EKNCLLDWNARYRIALGAAEGLCYLHHDCRPQIVHRDIKSNNILLDERFQAH-------V 942 Query 758 SDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 D G+ + S ++APE ++ D + FG LLE+ G+ Sbjct 943 GDFGLAKLIDLSYSKSMSAVAGSYGYIAPEYA--YTMKVTEKCDIYSFGVVLLELI-TGK 999 Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATL 844 P+Q + R P + Sbjct 1000 PPVQPL--EQGGDLVNWVRRSIRNMIPTIEMF 1029 >sp|A4K2W5|STK4_AOTNA Serine/threonine-protein kinase 4 OS=Aotus nancymaae OX=37293 GN=STK4 PE=3 SV=1 Length=487 Score = 228 bits (580), Expect = 2e-63, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 109/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V Y + TG++VA+K + + Q +EI I++ H++K Sbjct 35 KLGEGSYGSV----YKAIHKETGQIVAIKQVPVESDLQ---EIIKEISIMQQCDSHHVVK 87 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 88 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRK 145 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 146 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 203 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 249 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 +K C R T L+ Sbjct 250 WSDNFTDFVKQCLVKSPEQRATATQLLQ 277 Score = 199 bits (507), Expect = 7e-54, Method: Composition-based stats. Identities = 59/300 (20%), Positives = 96/300 (32%), Gaps = 44/300 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L + S + ++ L LG+G+ +VY+ + G Sbjct 17 LDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQ---------------------- 54 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K + + S+M Q H+ +G + + +V EY G + Sbjct 55 --IVAIKQVPVESD--LQEIIKEISIMQQCDSHHVVKYYGSYFKNTDLWIVMEYCGAGSV 110 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + Q L YL +H ++ NILL G Sbjct 111 SDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 163 Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D GV R + W+APE + + D W G T +E+ +G Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQE--IGYNCVADIWSLGITAIEMA-EG 220 Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P P R PE QCL P QR + +L+ Sbjct 221 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPF 280 >sp|Q8QFP8|LIMK1_CHICK LIM domain kinase 1 OS=Gallus gallus OX=9031 GN=LIMK1 PE=1 SV=1 Length=662 Score = 232 bits (592), Expect = 2e-63, Method: Composition-based stats. Identities = 73/306 (24%), Positives = 130/306 (42%), Gaps = 33/306 (11%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 +F L LG+G FG+ T+ TGE++ +K L + + + +E+ Sbjct 338 HRIFRPSDLIHGEVLGKGCFGQ----AIKVTHRETGEVMVMKEL-IRFDEETQRTFLKEV 392 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQ 1006 ++R L H +++K+ G EK L + EY+ G+LR + +Q + FA+ Sbjct 393 KVMRCLEHPNVLKFIGVLYK--EKRLNFITEYIKGGTLRGLIKSMDSHYPWSQRVSFAKD 450 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY-----------Y 1055 I GMAYLH+ + IHRDL + N L+ ++ V + DFGLA+ + + Sbjct 451 IAAGMAYLHSMNIIHRDLNSHNCLVRENKSVVVADFGLARLMVDEKNQPEHLQNLKKPDR 510 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 + R +W APE + + D++SFG+ L E++ + + + Sbjct 511 KKRYTVVGNPYWMAPEMINGRSYDEKVDIFSFGIVLCEIIGRVSADPDYLPRTTDFGLNV 570 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 +G + P CP + + C + + RP+F L L+T+ Sbjct 571 RGFLERY-------------CPPACPPSFFPIAACCCDLDPEKRPSFSKLEQWLETLRMH 617 Query 1176 YQGQAP 1181 + P Sbjct 618 LDIRLP 623 Score = 203 bits (517), Expect = 1e-53, Method: Composition-based stats. Identities = 57/308 (19%), Positives = 111/308 (36%), Gaps = 54/308 (18%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ LG+G + R G +V+K L Sbjct 343 PSDLIHGEVLGKGCFGQAIKVTHRETGE------------------------VMVMKELI 378 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + F + +M + H ++ GV + +TEY++ G L ++ H Sbjct 379 RFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKEKRLNFITEYIKGGTLRGLIKSMDSH 438 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 P + ++ A+ +A+ ++YL + N++H ++ N L+ + + ++D G+ Sbjct 439 YPWSQRVSFAKDIAAGMAYLHSMNIIHRDLNSHNCLVRE-------NKSVVVADFGLARL 491 Query 766 ALSRE------------------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 + + V W+APE + G S +D + FG L EI Sbjct 492 MVDEKNQPEHLQNLKKPDRKKRYTVVGNPYWMAPEMING--RSYDEKVDIFSFGIVLCEI 549 Query 808 C--FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILR 864 + R+ + R P+CP + + C +P +RPSF + + Sbjct 550 IGRVSADPDYLPRTTDFGLNVRGFLERYCPPACPPSFFPIAACCCDLDPEKRPSFSKLEQ 609 Query 865 DLTRLQPH 872 L L+ H Sbjct 610 WLETLRMH 617 >sp|Q863I2|OXSR1_PIG Serine/threonine-protein kinase OSR1 OS=Sus scrofa OX=9823 GN=OXSR1 PE=2 SV=1 Length=529 Score = 229 bits (583), Expect = 2e-63, Method: Composition-based stats. Identities = 73/293 (25%), Positives = 122/293 (42%), Gaps = 30/293 (10%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 P +K + +G G V P E VA+K + + +EI Sbjct 9 PWSINKDDYELQEVIGSGATAVVQAAYCTPKK----EKVAIKRINLEKCQTSMDELLKEI 64 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQ 999 + +H +I+ Y + E L LVM+ + GS+ D + + A Sbjct 65 QAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEAT 122 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--V 1057 + +++ EG+ YLH IHRD+ A N+LL D V+I DFG++ + G + R V Sbjct 123 IATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKV 182 Query 1058 REDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQS-PPTK--FLELIG 1113 R+ W APE +++ + + +D+WSFG+T EL T PP K L L Sbjct 183 RKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQN 242 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 T ++ E+L++ + ++ C + + RPT L+ Sbjct 243 DPPSLETGVQDKEMLKKYGK---------SFRKMISLCLQKDPEKRPTAAELL 286 Score = 177 bits (449), Expect = 8e-46, Method: Composition-based stats. Identities = 52/315 (17%), Positives = 102/315 (32%), Gaps = 61/315 (19%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +++ + +G G V ++ +V + Sbjct 10 WSINKDDYELQEVIGSGATAVV------------------------QAAYCTPKKEKVAI 45 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K ++ ++ + MSQ H ++ + V E +V + + G + ++ Sbjct 46 KRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIK 105 Query 701 R-------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 + G + A + +++ L YL +H +V NILL G Sbjct 106 HIVAKGEHKSGVLDEATIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG------- 158 Query 754 FIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 ++++D GV + R+ V W+APE + D W FG T Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKADIWSFGITA 217 Query 805 LEICFDGEAPLQSRSPSEKEHFY-----------QRQHRLPEPSCPQLATLTSQCLTYEP 853 +E+ G AP P + + + + + S CL +P Sbjct 218 IELA-TGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDP 276 Query 854 TQRPSFRTILRDLTR 868 +RP+ +LR Sbjct 277 EKRPTAAELLRHKFF 291 >sp|Q9LHP4|RGI1_ARATH LRR receptor-like serine/threonine-protein kinase RGI1 OS=Arabidopsis thaliana OX=3702 GN=RGI1 PE=1 SV=1 Length=1141 Score = 239 bits (611), Expect = 2e-63, Method: Composition-based stats. Identities = 77/316 (24%), Positives = 127/316 (40%), Gaps = 23/316 (7%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--- 932 P + R L + +G+G G V + GE++AVK L Sbjct 765 YKWQFTPFQKLNFSVDQIIRCLVEPNVIGKGCSGVVYRA-----DVDNGEVIAVKKLWPA 819 Query 933 -----KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 + R + E+ L T+ H++I+++ GCC ++ + L +Y+P GSL Sbjct 820 MVNGGHDEKTKNVRDSFSAEVKTLGTIRHKNIVRFLGCCWNRNTRLLM--YDYMPNGSLG 877 Query 988 DYLPRH---SIGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGD 1041 L S+ +G+AYLH +HRD+ A N+L+ D I D Sbjct 878 SLLHERRGSSLDWDLRYRILLGAAQGLAYLHHDCLPPIVHRDIKANNILIGLDFEPYIAD 937 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLAK V EG + R + APE K SDV+S+GV + E+LT Sbjct 938 FGLAKLVDEG-DIGRCSNTVAGSYGYIAPEYGYSMKITEKSDVYSYGVVVLEVLTGKQPI 996 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + + L+ + L + + R R +V C + RPT Sbjct 997 DPTVPEGIHLVDWVRQNRGSLEVLDSTLRS-RTEAEADEMMQVLGTALLCVNSSPDERPT 1055 Query 1162 FENLIPILKTVHEKYQ 1177 +++ +LK + ++ + Sbjct 1056 MKDVAAMLKEIKQERE 1071 Score = 186 bits (472), Expect = 1e-46, Method: Composition-based stats. Identities = 73/444 (16%), Positives = 149/444 (34%), Gaps = 71/444 (16%) Query 403 LELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSI------RDGIHGPLL 456 L +PS+ A+L+ +S++D S + L ++AP + ++ + G L Sbjct 623 LTGKIPSKIASLNKLSILDL-------SHNMLEGDLAPLANIENLVSLNISYNSFSGYLP 675 Query 457 EPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVL 516 + + +L P+D +S LT + + D + R RK + + Sbjct 676 DNKLFRQLSPQDLEGNKKLCSSTQDSCFLTYRKGNGLGDDGDASRTRKLRLTLALLITLT 735 Query 517 EGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL 576 L+ G R + ++ + + LN Sbjct 736 V------------------VLMILGAVAVIRARRNIDNERDSELGETYKWQFTPFQKLNF 777 Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S R + + + +G+G VY D + G++ L P G Sbjct 778 SVDQIIRC----LVEPNVIGKGCSGVVYRA--------DVDNGEVIAVKKLWPAMVNGGH 825 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 D ++ +F + + H ++ G C +++ +Y+ +G L Sbjct 826 --------DEKTKNVRDSFSAEVKTLGTIRHKNIVRFLGCCWNRNTRLLMYDYMPNGSLG 877 Query 697 VWLRRERG-HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752 L RG + + + A L+YL + +VH ++ NIL+ G Sbjct 878 SLLHERRGSSLDWDLRYRILLGAAQGLAYLHHDCLPPIVHRDIKANNILI-------GLD 930 Query 753 PFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 ++D G+ + ++APE G + ++ D + +G +LE Sbjct 931 FEPYIADFGLAKLVDEGDIGRCSNTVAGSYGYIAPEY--GYSMKITEKSDVYSYGVVVLE 988 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQ 830 + G+ P+ P + Sbjct 989 VL-TGKQPIDPTVPEGIHLVDWVR 1011 >sp|Q9LYX1|LRK82_ARATH L-type lectin-domain containing receptor kinase VIII.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK82 PE=2 SV=1 Length=711 Score = 233 bits (595), Expect = 2e-63, Method: Composition-based stats. Identities = 68/290 (23%), Positives = 118/290 (41%), Gaps = 29/290 (10%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R +G G FG V Y +GE++A+K Q + + E+ ++ TL Sbjct 372 DCFSSSRVIGNGAFGTV----YKGILQDSGEIIAIKRCSHIS--QGNTEFLSELSLIGTL 425 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMA 1012 H ++++ +G C ++GE + L+ + +P GSL L + + +A Sbjct 426 RHRNLLRLQGYCREKGE--ILLIYDLMPNGSLDKALYESPTTLPWPHRRKILLGVASALA 483 Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH IHRD+ N++LD + K+GDFGLA+ + + A Sbjct 484 YLHQECENQIIHRDVKTSNIMLDANFNPKLGDFGLARQTEHDKSPDAT--AAAGTMGYLA 541 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-------PTKFLELIGIAQGQMTVL 1122 PE L + +DV+S+G + E+ T P P L+ G Sbjct 542 PEYLLTGRATEKTDVFSYGAVVLEVCTGRRPITRPEPEPGLRPGLRSSLVDWVWGLYREG 601 Query 1123 RLTELLERGERLPRPDKCPCEVYHLM---KNCWETEASFRPTFENLIPIL 1169 +L ++ + P E+ +M C + + RPT +++ IL Sbjct 602 KLLTAVDERL----SEFNPEEMSRVMMVGLACSQPDPVTRPTMRSVVQIL 647 Score = 216 bits (551), Expect = 8e-58, Method: Composition-based stats. Identities = 63/323 (20%), Positives = 111/323 (34%), Gaps = 67/323 (21%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 SPR +L ++ + +G G VY+G L+ G Sbjct 358 SPREFTYKEL---KLATDCFSSSRVIGNGAFGTVYKGILQDSGE---------------- 398 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 + +K F SL+ + H +L + G C E +++ + Sbjct 399 --------IIAIKRCSHIS-QGNTEFLSELSLIGTLRHRNLLRLQGYCREKGEILLIYDL 449 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLG 746 + +G LD L +P + + +ASAL+YL ++H +V NI+L Sbjct 450 MPNGSLDKALYESPTTLPWPHRRKILLGVASALAYLHQECENQIIHRDVKTSNIMLD--- 506 Query 747 LAEGTSPFIKLSDPGVGLGALSREE-----RVERIPWLAPECLPGGANSLSTAMDKWGFG 801 + KL D G+ + + +LAPE L G + D + +G Sbjct 507 ----ANFNPKLGDFGLARQTEHDKSPDATAAAGTMGYLAPEYLLTGRA--TEKTDVFSYG 560 Query 802 ATLLEICFDGEA-----PLQSRSP--------------SEKEHFYQRQHRLPEPSCPQLA 842 A +LE+C P P E + RL E + +++ Sbjct 561 AVVLEVCTGRRPITRPEPEPGLRPGLRSSLVDWVWGLYREGKLLTAVDERLSEFNPEEMS 620 Query 843 TLTS---QCLTYEPTQRPSFRTI 862 + C +P RP+ R++ Sbjct 621 RVMMVGLACSQPDPVTRPTMRSV 643 >sp|Q5R495|OXSR1_PONAB Serine/threonine-protein kinase OSR1 OS=Pongo abelii OX=9601 GN=OXSR1 PE=2 SV=1 Length=527 Score = 229 bits (583), Expect = 2e-63, Method: Composition-based stats. Identities = 71/293 (24%), Positives = 122/293 (42%), Gaps = 30/293 (10%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 P ++ + +G G V P E VA+K + + +EI Sbjct 9 PWSINRDDYELQEVIGSGATAVVQAAYCAPKK----EKVAIKRINLEKCQTSMDELLKEI 64 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQ 999 + +H +I+ Y + E L LVM+ + GS+ D + + + Sbjct 65 QAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEST 122 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--V 1057 + +++ EG+ YLH IHRD+ A N+LL D V+I DFG++ + G + R V Sbjct 123 IATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKV 182 Query 1058 REDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQS-PPTK--FLELIG 1113 R+ W APE +++ + + +D+WSFG+T EL T PP K L L Sbjct 183 RKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQN 242 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 T ++ E+L++ + ++ C + + RPT L+ Sbjct 243 DPPSLETGVQDKEMLKKYGK---------SFRKMISLCLQKDPEKRPTAAELL 286 Score = 178 bits (451), Expect = 4e-46, Method: Composition-based stats. Identities = 51/315 (16%), Positives = 102/315 (32%), Gaps = 61/315 (19%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +++ + +G G V ++ +V + Sbjct 10 WSINRDDYELQEVIGSGATAVV------------------------QAAYCAPKKEKVAI 45 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K ++ ++ + MSQ H ++ + V E +V + + G + ++ Sbjct 46 KRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIK 105 Query 701 R-------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 + G + + + +++ L YL +H +V NILL G Sbjct 106 HIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG------- 158 Query 754 FIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 ++++D GV + R+ V W+APE + D W FG T Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKADIWSFGITA 217 Query 805 LEICFDGEAPLQSRSPSEKEHFY-----------QRQHRLPEPSCPQLATLTSQCLTYEP 853 +E+ G AP P + + + + + S CL +P Sbjct 218 IELA-TGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDP 276 Query 854 TQRPSFRTILRDLTR 868 +RP+ +LR Sbjct 277 EKRPTAAELLRHKFF 291 >sp|O95747|OXSR1_HUMAN Serine/threonine-protein kinase OSR1 OS=Homo sapiens OX=9606 GN=OXSR1 PE=1 SV=1 Length=527 Score = 229 bits (583), Expect = 2e-63, Method: Composition-based stats. Identities = 71/293 (24%), Positives = 122/293 (42%), Gaps = 30/293 (10%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 P ++ + +G G V P E VA+K + + +EI Sbjct 9 PWSINRDDYELQEVIGSGATAVVQAAYCAPKK----EKVAIKRINLEKCQTSMDELLKEI 64 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQ 999 + +H +I+ Y + E L LVM+ + GS+ D + + + Sbjct 65 QAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEST 122 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--V 1057 + +++ EG+ YLH IHRD+ A N+LL D V+I DFG++ + G + R V Sbjct 123 IATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKV 182 Query 1058 REDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQS-PPTK--FLELIG 1113 R+ W APE +++ + + +D+WSFG+T EL T PP K L L Sbjct 183 RKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQN 242 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 T ++ E+L++ + ++ C + + RPT L+ Sbjct 243 DPPSLETGVQDKEMLKKYGK---------SFRKMISLCLQKDPEKRPTAAELL 286 Score = 178 bits (451), Expect = 4e-46, Method: Composition-based stats. Identities = 51/315 (16%), Positives = 102/315 (32%), Gaps = 61/315 (19%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +++ + +G G V ++ +V + Sbjct 10 WSINRDDYELQEVIGSGATAVV------------------------QAAYCAPKKEKVAI 45 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K ++ ++ + MSQ H ++ + V E +V + + G + ++ Sbjct 46 KRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIK 105 Query 701 R-------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 + G + + + +++ L YL +H +V NILL G Sbjct 106 HIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG------- 158 Query 754 FIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 ++++D GV + R+ V W+APE + D W FG T Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKADIWSFGITA 217 Query 805 LEICFDGEAPLQSRSPSEKEHFY-----------QRQHRLPEPSCPQLATLTSQCLTYEP 853 +E+ G AP P + + + + + S CL +P Sbjct 218 IELA-TGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDP 276 Query 854 TQRPSFRTILRDLTR 868 +RP+ +LR Sbjct 277 EKRPTAAELLRHKFF 291 >sp|A7E3S4|RAF1_BOVIN RAF proto-oncogene serine/threonine-protein kinase OS=Bos taurus OX=9913 GN=RAF1 PE=2 SV=1 Length=648 Score = 232 bits (591), Expect = 2e-63, Method: Composition-based stats. Identities = 79/333 (24%), Positives = 136/333 (41%), Gaps = 35/333 (11%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 + T P+ R + + + +S + +G G F Sbjct 305 WSQPKTPAPAQRERAPGSST----QEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF 360 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 G V + VAVK LK D P+ ++ E+ +LR H +I+ + G Sbjct 361 GTVYKGKWHG-------DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYM- 412 Query 968 DQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ IHRD+ Sbjct 413 --TKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMK 470 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYAS 1082 + N+ L VKIGDFGLA +V E + W APE ++ F + S Sbjct 471 SNNIFLHEGLTVKIGDFGLATVKSRWSGSQQV-EQPTGSILWMAPEVIRMQDNNPFSFQS 529 Query 1083 DVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 DV+S+G+ LYEL+T + + ++G + +L + C Sbjct 530 DVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYK------------NC 577 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 P + L+ +C + RP F ++ ++ + Sbjct 578 PKAMKRLVADCVKKVKEERPLFPQILSSIELLQ 610 Score = 222 bits (565), Expect = 5e-60, Method: Composition-based stats. Identities = 70/367 (19%), Positives = 126/367 (34%), Gaps = 62/367 (17%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 R + N I RG R S + ++ E+ + +G G+ VY+G+ Sbjct 316 RERAPGSSTQEKNKIRPRGQRDSSY--------YWEIEASEVMLSTRIGSGSFGTVYKGK 367 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQ 664 + V +K+L DP+ AF +++ + Sbjct 368 WHGD---------------------------VAVKILKVVDPTPEQFQ-AFRNEVAVLRK 399 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 H ++ G + +VT++ E L L + M + +A+Q A + Y Sbjct 400 TRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778 L KN++H ++ NI L +K+ D G+ G+ E+ I W Sbjct 459 LHAKNIIHRDMKSNNIFLHEGL-------TVKIGDFGLATVKSRWSGSQQVEQPTGSILW 511 Query 779 LAPECLPGGA-NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------ 831 +APE + N S D + +G L E+ GE P + ++ F + Sbjct 512 MAPEVIRMQDNNPFSFQSDVYSYGIVLYELM-TGELPYSHINNRDQIIFMVGRGYASPDL 570 Query 832 -RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 +L + + L + C+ +RP F IL + LQ + + S Sbjct 571 SKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAH 630 Query 891 VFHKRYL 897 Sbjct 631 TEDINAC 637 >sp|O04533|LRK52_ARATH Putative L-type lectin-domain containing receptor kinase V.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK52 PE=3 SV=1 Length=656 Score = 232 bits (591), Expect = 2e-63, Method: Composition-based stats. Identities = 72/277 (26%), Positives = 117/277 (42%), Gaps = 16/277 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FGKV + + +AVK + D Q + EI + L H +++ Sbjct 340 LGKGGFGKV----FKGILPLSSIPIAVKKISHD-SRQGMREFLAEIATIGRLRHPDLVRL 394 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018 G C +GE L LV +++P GSL +L P + +Q + + G+ YLH Q Sbjct 395 LGYCRRKGE--LYLVYDFMPKGSLDKFLYNQPNQILDWSQRFNIIKDVASGLCYLHQQWV 452 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ N+LLD + K+GDFGLAK G + + + +PE + Sbjct 453 QVIIHRDIKPANILLDENMNAKLGDFGLAKLCDHGIDSQT--SNVAGTFGYISPELSRTG 510 Query 1077 KFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 K +SDV++FGV + E+ + L + ++++ Sbjct 511 KSSTSSDVFAFGVFMLEITCGRRPIGPRGSPSEMVLTDWVLDCWDSGDILQVVDEKLGHR 570 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + V L C A+ RP+ ++I L V Sbjct 571 YLAEQVTLVLKLGLLCSHPVAATRPSMSSVIQFLDGV 607 Score = 220 bits (561), Expect = 2e-59, Method: Composition-based stats. Identities = 59/308 (19%), Positives = 105/308 (34%), Gaps = 59/308 (19%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + K LG+G V++G L + + + +K Sbjct 329 IATKGFKNSEVLGKGGFGKVFKGILPL------------------------SSIPIAVKK 364 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + F + + ++ H L + G C R E +V +++ G LD +L + Sbjct 365 ISHDSRQGMREFLAEIATIGRLRHPDLVRLLGYCRRKGELYLVYDFMPKGSLDKFLYNQP 424 Query 704 GH-VPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + + + + + +AS L YL + ++H ++ NILL + KL D Sbjct 425 NQILDWSQRFNIIKDVASGLCYLHQQWVQVIIHRDIKPANILLDE-------NMNAKLGD 477 Query 760 PGVGL----GALSREERV-ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ G S+ V +++PE G + ST+ D + FG +LEI Sbjct 478 FGLAKLCDHGIDSQTSNVAGTFGYISPELSRTGKS--STSSDVFAFGVFMLEITCGRRPI 535 Query 815 LQSRSPSEKEHFYQR-----------------QHRLPEPSCPQLATLTSQCLTYEPTQRP 857 SPSE HR + L C RP Sbjct 536 GPRGSPSEMVLTDWVLDCWDSGDILQVVDEKLGHRYLAEQVTLVLKLGLLCSHPVAATRP 595 Query 858 SFRTILRD 865 S ++++ Sbjct 596 SMSSVIQF 603 >sp|Q5TCX8|M3K21_HUMAN Mitogen-activated protein kinase kinase kinase 21 OS=Homo sapiens OX=9606 GN=MAP3K21 PE=1 SV=3 Length=1036 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 86/308 (28%), Positives = 129/308 (42%), Gaps = 56/308 (18%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR---SGWKQEIDILRTLYHEHI 959 +G G FG+V + G+ VAVKA + D ++E + L H +I Sbjct 130 IGAGGFGQVYRATWQ------GQEVAVKAARQDPEQDAAAAAESVRREARLFAMLRHPNI 183 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------------IGLAQLLLFA 1004 I+ +G C Q L LV+E+ G+L L + I L+ +A Sbjct 184 IELRGVCLQQ--PHLCLVLEFARGGALNRALAAANAAPDPRAPGPRRARRIPPHVLVNWA 241 Query 1005 QQICEGMAYLHAQ---HYIHRDLAARNVLLDN--------DRLVKIGDFGLAKAVPEGHE 1053 QI GM YLH + +HRDL + N+LL ++ +KI DFGLA+ Sbjct 242 VQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLAR-----EW 296 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 + + W APE +K F SD+WS+GV L+ELLT P + ++ + Sbjct 297 HRTTKMSTAGTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTG-----EVPYRGIDGLA 351 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 +A G LP P CP LMK CW+ + RP+F ++ L + Sbjct 352 VAYGVAVN---------KLTLPIPSTCPEPFAKLMKECWQQDPHIRPSFALILEQLTAIE 402 Query 1174 EKYQGQAP 1181 + P Sbjct 403 GAVMTEMP 410 Score = 207 bits (528), Expect = 1e-53, Method: Composition-based stats. Identities = 82/466 (18%), Positives = 152/466 (33%), Gaps = 58/466 (12%) Query 514 FVLEGWGRSFPSVR--ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASP 571 + E G S+R +L L +GD+ + + +N + ASP Sbjct 47 YDYEARGEDELSLRRGQLVEVLSQDAAVSGDEGWWAGQVQRRLGIFPANYVAPCRPAASP 106 Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 S V + + +G G VY Sbjct 107 APPPSRPSSPVHVAFERLELKELIGAGGFGQVYRATW----------------------- 143 Query 632 DRGQELRVVLKVLDPSHHD----IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 Q V +K A + A L + + H ++ + GVC++ P +V Sbjct 144 ---QGQEVAVKAARQDPEQDAAAAAESVRREARLFAMLRHPNIIELRGVCLQQPHLCLVL 200 Query 688 EYVEHG-------------PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV--- 731 E+ G R +P + A Q+A + YL + V Sbjct 201 EFARGGALNRALAAANAAPDPRAPGPRRARRIPPHVLVNWAVQIARGMLYLHEEAFVPIL 260 Query 732 HGNVCGRNILLARLGLAEGT-SPFIKLSDPGVGLG--ALSREERVERIPWLAPECLPGGA 788 H ++ NILL + + +K++D G+ ++ W+APE + Sbjct 261 HRDLKSSNILLLEKIEHDDICNKTLKITDFGLAREWHRTTKMSTAGTYAWMAPEVIKSSL 320 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLT 845 S D W +G L E+ GE P + + + +P A L Sbjct 321 --FSKGSDIWSYGVLLWELL-TGEVPYRGIDGLAVAYGVAVNKLTLPIPSTCPEPFAKLM 377 Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 +C +P RPSF IL LT ++ + ++ + S D + ++ ++R + Sbjct 378 KECWQQDPHIRPSFALILEQLTAIEGAVMTEMPQESFHSMQDDWKLEIQQMFDELRTKEK 437 Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 + + E + +K + + ++E++IL Sbjct 438 ELRSREEELTRAALQQKSQEEL-LKRREQQLAEREIDVLERELNIL 482 >sp|P92937|CIPKF_ARATH CBL-interacting serine/threonine-protein kinase 15 OS=Arabidopsis thaliana OX=3702 GN=CIPK15 PE=1 SV=2 Length=421 Score = 225 bits (574), Expect = 2e-63, Method: Composition-based stats. Identities = 62/269 (23%), Positives = 113/269 (42%), Gaps = 26/269 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHI 959 LG+G F KV Y + TG+ VA+K + + + K+EI +R L H +I Sbjct 17 FLGQGTFAKV----YHARHLKTGDSVAIKVIDKERILKVGMTEQIKREISAMRLLRHPNI 72 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 ++ + + + VME+V G L + + + + QQ+ + + H++ Sbjct 73 VELHEVMATKSK--IYFVMEHVKGGELFNKVSTGKLREDVARKYFQQLVRAVDFCHSRGV 130 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 HRDL N+LLD +KI DFGL+ + + +P + APE + + Sbjct 131 CHRDLKPENLLLDEHGNLKISDFGLSALSDSRRQDGLLHTTCGTPA-YVAPEVISRNGYD 189 Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 + +DVWS GV L+ LL + ++ L + + + E + P+ Sbjct 190 GFKADVWSCGVILFVLLAGYLPFRD---------------SNLMELYKKIGKAE-VKFPN 233 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L+K + + R + E ++ Sbjct 234 WLAPGAKRLLKRILDPNPNTRVSTEKIMK 262 Score = 182 bits (461), Expect = 2e-48, Method: Composition-based stats. Identities = 57/287 (20%), Positives = 93/287 (32%), Gaps = 45/287 (16%) Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---H 648 LGQGT VY R G V +KV+D Sbjct 15 GKFLGQGTFAKVYHARHLKTGDS------------------------VAIKVIDKERILK 50 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 + S M + H ++ +H V + V E+V+ G L + G + Sbjct 51 VGMTEQIKREISAMRLLRHPNIVELHEVMATKSKIYFVMEHVKGGELFN--KVSTGKLRE 108 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 QQL A+ + ++ + H ++ N+LL G +K+SD G+ + S Sbjct 109 DVARKYFQQLVRAVDFCHSRGVCHRDLKPENLLLDEHG-------NLKISDFGLSALSDS 161 Query 769 R------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 R ++APE + D W G L + G P + + E Sbjct 162 RRQDGLLHTTCGTPAYVAPEVISRNGYD-GFKADVWSCGVIL-FVLLAGYLPFRDSNLME 219 Query 823 KE-HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + + + P P L + L P R S I++ Sbjct 220 LYKKIGKAEVKFPNWLAPGAKRLLKRILDPNPNTRVSTEKIMKSSWF 266 >sp|Q5W736|CIPKI_ORYSJ CBL-interacting protein kinase 18 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK18 PE=2 SV=1 Length=457 Score = 226 bits (577), Expect = 2e-63, Method: Composition-based stats. Identities = 57/269 (21%), Positives = 107/269 (40%), Gaps = 26/269 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960 LG+G F KV Y N T + VA+K + D + K+EI +++ + H +I+ Sbjct 21 LGQGTFAKV----YHGRNIVTSQSVAIKVIDKDKIFKVGLMDQIKREISVMKLVRHPNIV 76 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + + + + V+EYV G L + + + + + QQ+ + + H++ Sbjct 77 QLYEVMATKSK--IYFVLEYVKGGELFNKVAKGRLKEDAARKYFQQLVSAVDFCHSRGVY 134 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 HRDL N+L+D + +KI DFGL+ + + +P + APE + + Sbjct 135 HRDLKPENLLVDENGNLKITDFGLSALAESRRQDGLLHTTCGTPA-YVAPEVISRKGYDG 193 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 D WS GV L+ L+ Q ++ + + + E P Sbjct 194 VKVDTWSCGVILFVLMAGYLPFQD---------------SNLMEMYRKIGKAE-FKCPAW 237 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPI 1168 +V L+ + R ++ Sbjct 238 FSSDVRKLVSRILDPNPRSRMPITKIMET 266 Score = 189 bits (479), Expect = 2e-50, Method: Composition-based stats. Identities = 58/295 (20%), Positives = 99/295 (34%), Gaps = 45/295 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + + LGQGT VY G R+ V +KV Sbjct 10 ILLRRYEIGKLLGQGTFAKVYHG------------------------RNIVTSQSVAIKV 45 Query 644 LDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 +D + S+M V H ++ ++ V + V EYV+ G L + Sbjct 46 IDKDKIFKVGLMDQIKREISVMKLVRHPNIVQLYEVMATKSKIYFVLEYVKGGELFN--K 103 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 +G + QQL SA+ + ++ + H ++ N+L+ G +K++D Sbjct 104 VAKGRLKEDAARKYFQQLVSAVDFCHSRGVYHRDLKPENLLVDENG-------NLKITDF 156 Query 761 GVGLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ A SR ++APE + +D W G L + G P Sbjct 157 GLSALAESRRQDGLLHTTCGTPAYVAPEVISRKGYD-GVKVDTWSCGVIL-FVLMAGYLP 214 Query 815 LQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 Q + E + + + P + L S+ L P R I+ Sbjct 215 FQDSNLMEMYRKIGKAEFKCPAWFSSDVRKLVSRILDPNPRSRMPITKIMETYWF 269 >sp|P92958|KIN11_ARATH SNF1-related protein kinase catalytic subunit alpha KIN11 OS=Arabidopsis thaliana OX=3702 GN=KIN11 PE=1 SV=1 Length=512 Score = 228 bits (581), Expect = 2e-63, Method: Composition-based stats. Identities = 77/292 (26%), Positives = 119/292 (41%), Gaps = 30/292 (10%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KAD 935 + + + ++ K + LG G FGKV + + TG VA+K L + Sbjct 1 MDHSSNRFGNNGVESILPNYKLGKTLGIGSFGKVKI----AEHVVTGHKVAIKILNRRKI 56 Query 936 CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHS 994 + ++EI ILR H HII+ E + + +VMEYV G L DY+ + Sbjct 57 KNMEMEEKVRREIKILRLFMHPHIIRQYEVIETTSD--IYVVMEYVKSGELFDYIVEKGR 114 Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + + F QQI G+ Y H +HRDL N+LLD+ +KI DFGL+ + +G Sbjct 115 LQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLDSRCNIKIADFGLSNVMRDG--- 171 Query 1055 YRVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 + ++ SP + APE + + DVWS GV LY LL Sbjct 172 HFLKTSCGSPN-YAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDE--------- 221 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + L + ++ G P E L+ + R T + Sbjct 222 ------NIPNLFKKIKGGI-YTLPSHLSSEARDLIPRMLIVDPVKRITIPEI 266 Score = 176 bits (445), Expect = 2e-45, Method: Composition-based stats. Identities = 49/323 (15%), Positives = 96/323 (30%), Gaps = 39/323 (12%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP- 646 LG G+ V V G +V +K+L+ Sbjct 19 NYKLGKTLGIGSFGKVKIAEHVVTGH------------------------KVAIKILNRR 54 Query 647 --SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + ++ ++ H H+ + V + +V EYV+ G L ++ E+G Sbjct 55 KIKNMEMEEKVRREIKILRLFMHPHIIRQYEVIETTSDIYVVMEYVKSGELFDYI-VEKG 113 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763 + QQ+ S + Y +VH ++ N+LL + IK++D G+ Sbjct 114 RLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENLLLD-------SRCNIKIADFGLSN 166 Query 764 --LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + + APE + G + +D W G L + P+ Sbjct 167 VMRDGHFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYALLCGTLPFDDENIPN 225 Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 + + LP + L + L +P +R + I + ++ Sbjct 226 LFKKIKGGIYTLPSHLSSEARDLIPRMLIVDPVKRITIPEIRQHRWFQTHLPRYLAVSPP 285 Query 882 PDSPASDPTVFHKRYLKKIRDLG 904 + Sbjct 286 DTVEQAKKINEEIVQEVVNMGFD 308 >sp|Q91048|PTK7_CHICK Inactive tyrosine-protein kinase 7 OS=Gallus gallus OX=9031 GN=PTK7 PE=2 SV=1 Length=1051 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 87/298 (29%), Positives = 133/298 (45%), Gaps = 29/298 (10%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE-MVAVKALKADCGPQHR 941 A D F + L+ I LG G FG+V L D GE +V VK+L Q + Sbjct 763 RHSARDKMHFPRSNLQTITTLGRGEFGEVFLAKAKGAEDAEGEALVLVKSL-QTRDEQLQ 821 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----------P 991 +++E ++ L H ++++ G C + +V+EYV LG L+ +L Sbjct 822 LDFRREAEMFGKLNHVNVVRLLGLCREAEPH--YMVLEYVDLGDLKQFLRISKSKDESLK 879 Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 + + Q+ GM +L ++HRDLAARN L+ R VK+ L+K V Sbjct 880 PQPLSTKHKVSLCTQVALGMEHLSNGRFVHRDLAARNCLVSAQRQVKVSALSLSKDVYNS 939 Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111 Y+ P+ W PE + E +F SDVWSFGV ++E+ T + +P L Sbjct 940 EYYHF--RQAWIPLRWMPPEAVLEDEFSTKSDVWSFGVLMWEVFTQGEMPYAPLADDEVL 997 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 G+ G+ +LP+P+ CP + LM+ CW RP+F L L Sbjct 998 AGLKSGKT-------------KLPQPEGCPSRLTKLMQRCWAPSPKDRPSFSELAAAL 1042 Score = 219 bits (557), Expect = 4e-57, Method: Composition-based stats. Identities = 64/321 (20%), Positives = 117/321 (36%), Gaps = 44/321 (14%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 + + +S + S + + ++ LG+G V+ + + Sbjct 746 QEEVALTNLGSSSGASKRHSARDKMHFPRSNLQTITTLGRGEFGEVFLAKAKG------- 798 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 D E V++K L + L F A + +++H ++ + G+C Sbjct 799 ------------AEDAEGEALVLVKSLQTRDEQLQLDFRREAEMFGKLNHVNVVRLLGLC 846 Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGH--------VPMAWKMVVAQQLASALSYLENKN 729 + MV EYV+ G L +LR + + K+ + Q+A + +L N Sbjct 847 REAEPHYMVLEYVDLGDLKQFLRISKSKDESLKPQPLSTKHKVSLCTQVALGMEHLSNGR 906 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECL 784 VH ++ RN L++ +K+S + + E R + W+ PE + Sbjct 907 FVHRDLAARNCLVS-------AQRQVKVSALSLSKDVYNSEYYHFRQAWIPLRWMPPEAV 959 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK---EHFYQRQHRLPEPSCPQL 841 + ST D W FG + E+ GE P + E + + PE +L Sbjct 960 LE--DEFSTKSDVWSFGVLMWEVFTQGEMPYAPLADDEVLAGLKSGKTKLPQPEGCPSRL 1017 Query 842 ATLTSQCLTYEPTQRPSFRTI 862 L +C P RPSF + Sbjct 1018 TKLMQRCWAPSPKDRPSFSEL 1038 >sp|O22971|CIPKD_ARATH CBL-interacting serine/threonine-protein kinase 13 OS=Arabidopsis thaliana OX=3702 GN=CIPK13 PE=1 SV=2 Length=502 Score = 228 bits (580), Expect = 3e-63, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 113/268 (42%), Gaps = 26/268 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960 LG G F KV L N +GE VA+K + + + K+EI ILR + H +I+ Sbjct 63 LGHGSFAKVYL----ARNIHSGEDVAIKVIDKEKIVKSGLAGHIKREISILRRVRHPYIV 118 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + + + +VMEYV G L + + R + + QQ+ +A+ H++ Sbjct 119 HLLEVMATKTK--IYIVMEYVRGGELYNTVARGRLREGTARRYFQQLISSVAFCHSRGVY 176 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF-Y 1079 HRDL N+LLD+ VK+ DFGL+ V E + + + + APE L + Sbjct 177 HRDLKLENLLLDDKGNVKVSDFGLS-VVSEQLKQEGICQTFCGTPAYLAPEVLTRKGYEG 235 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS GV L+ L+ +L + + +G + P Sbjct 236 AKADIWSCGVILFVLMAGYLPFDD---------------KNILVMYTKIYKG-QFKCPKW 279 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 E+ L+ +T R T ++ Sbjct 280 FSPELARLVTRMLDTNPDTRITIPEIMK 307 Score = 181 bits (458), Expect = 3e-47, Method: Composition-based stats. Identities = 59/332 (18%), Positives = 106/332 (32%), Gaps = 43/332 (13%) Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 ++P + + + + LG G+ VY R G Sbjct 32 TNKETSTPESPRSPRTPQGSILMDKYEIGKLLGHGSFAKVYLARNIHSGED--------- 82 Query 624 EDPLVPGRDRGQELRVVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680 V +KV+D +A S++ +V H ++ + V Sbjct 83 ---------------VAIKVIDKEKIVKSGLAGHIKREISILRRVRHPYIVHLLEVMATK 127 Query 681 PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNI 740 + +V EYV G L RG + QQL S++++ ++ + H ++ N+ Sbjct 128 TKIYIVMEYVRGGELYN--TVARGRLREGTARRYFQQLISSVAFCHSRGVYHRDLKLENL 185 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTA 794 LL G +K+SD G+ + + + +LAPE L Sbjct 186 LLDDKG-------NVKVSDFGLSVVSEQLKQEGICQTFCGTPAYLAPEVLTRKGYE-GAK 237 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854 D W G L + Y+ Q + P+ P+LA L ++ L P Sbjct 238 ADIWSCGVILFVLMAGYLPFDDKNILVMYTKIYKGQFKCPKWFSPELARLVTRMLDTNPD 297 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 R + I++ + N Sbjct 298 TRITIPEIMKHRWFKKGFKHVKFYIENDKLCR 329 >sp|Q9V3Q6|M3K7_DROME Mitogen-activated protein kinase kinase kinase 7 OS=Drosophila melanogaster OX=7227 GN=Tak1 PE=2 SV=1 Length=678 Score = 232 bits (592), Expect = 3e-63, Method: Composition-based stats. Identities = 72/284 (25%), Positives = 125/284 (44%), Gaps = 38/284 (13%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G +G V + ++VAVK A + ++E+ L + H +II Sbjct 24 KVGHGSYGVVCKAVWR------DKLVAVKEFFASA---EQKDIEKEVKQLSRVKHPNIIA 74 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQ- 1017 G +++ L+ME+ GSL ++L + + LA + +A+Q EG+AYLHA Sbjct 75 LHGI--SSYQQATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMT 132 Query 1018 --HYIHRDLAARNVLLDNDR-LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRD+ N+LL N +KI DFG + + + W APE + Sbjct 133 PKPLIHRDVKPLNLLLTNKGRNLKICDFG------TVADKSTMMTNNRGSAAWMAPEVFE 186 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 K+ D++S+ + L+E+L+ +G + + +GER Sbjct 187 GSKYTEKCDIFSWAIVLWEVLSRKQPF--------------KGIDNAYTIQWKIYKGERP 232 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 P CP + LM CW+T RP+ + ++ ++ + + Y G Sbjct 233 PLLTTCPKRIEDLMTACWKTVPEDRPSMQYIVGVMHEIVKDYTG 276 Score = 201 bits (512), Expect = 6e-53, Method: Composition-based stats. Identities = 62/305 (20%), Positives = 111/305 (36%), Gaps = 45/305 (15%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 T +L L VD EIT +G G+ V + R + Sbjct 3 TASLDALQAAYVDFSEITLREKVGHGSYGVVCKAVWRDK--------------------- 41 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 V +K S + + +S+V H ++ +HG+ ++ E+ E Sbjct 42 -----LVAVKEFFASAEQKDIE--KEVKQLSRVKHPNIIALHGISSYQQATYLIMEFAEG 94 Query 693 GPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLA 748 G L +L + + +A M A+Q A L+YL K L+H +V N+LL G Sbjct 95 GSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMTPKPLIHRDVKPLNLLLTNKG-- 152 Query 749 EGTSPFIKLSDPG-VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+ D G V + W+APE G + + D + + L E+ Sbjct 153 ----RNLKICDFGTVADKSTMMTNNRGSAAWMAPEVFEG--SKYTEKCDIFSWAIVLWEV 206 Query 808 CFDGEAPLQSRSPS---EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + P + + + + + + L ++ L + C P RPS + I+ Sbjct 207 LSR-KQPFKGIDNAYTIQWKIYKGERPPLLTTCPKRIEDLMTACWKTVPEDRPSMQYIVG 265 Query 865 DLTRL 869 + + Sbjct 266 VMHEI 270 >sp|Q0PW40|CRK13_ARATH Cysteine-rich receptor-like protein kinase 13 OS=Arabidopsis thaliana OX=3702 GN=CRK13 PE=2 SV=1 Length=673 Score = 232 bits (591), Expect = 3e-63, Method: Composition-based stats. Identities = 70/296 (24%), Positives = 118/296 (40%), Gaps = 23/296 (8%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 LG G G V G+ +AVK L ++ Q + +K Sbjct 347 QYKFKTIETATNNFSERLGHGGSGHVFKGRL-----PDGKEIAVKRL-SEKTEQSKKEFK 400 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLL 1001 E+ ++ L H ++++ G +GE+ + +V EY+P SL L + + + Sbjct 401 NEVVLVAKLQHRNLVRLLG-FSVKGEEKI-IVYEYLPNRSLDYILFDPTKQGELDWKKRY 458 Query 1002 LFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 G+ YLH IHRDL A N+LLD K+ DFG A+ Sbjct 459 KIIGGTARGILYLHQDSQPTIIHRDLKAGNILLDAHMNPKVADFGTARIFGMDQSVAITA 518 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQ 1116 +P + APE ++ +F SDV+S+GV + E++ S SP F+ + Sbjct 519 NAAGTP-GYMAPEYMELGEFSMKSDVYSYGVLVLEIICGKRNTSFSSPVQNFVTYVWRLW 577 Query 1117 GQMTVLRLTEL-LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 T L L + + + + H+ C + E + RP F ++ +L + Sbjct 578 KSGTPLNLVDATIAENYK----SEEVIRCIHIALLCVQEEPTDRPDFSIIMSMLTS 629 Score = 216 bits (550), Expect = 6e-58, Method: Composition-based stats. Identities = 65/341 (19%), Positives = 112/341 (33%), Gaps = 69/341 (20%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 + + + + S R+L F ++ LG G +V++GRL Sbjct 326 KEKPYQEVELNQTGITSVRSLQYK---FKTIETATNNFSERLGHGGSGHVFKGRLPDGK- 381 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 + +K L F L++++ H +L + Sbjct 382 ------------------------EIAVKRLSEKTEQSKKEFKNEVVLVAKLQHRNLVRL 417 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN-- 729 G V+G E I+V EY+ + LD L + W + + A + YL + Sbjct 418 LGFSVKGEEKIIVYEYLPNRSLDYILFDPTKQGELDWKKRYKIIGGTARGILYLHQDSQP 477 Query 730 -LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPE 782 ++H ++ NILL K++D G ++APE Sbjct 478 TIIHRDLKAGNILLD-------AHMNPKVADFGTARIFGMDQSVAITANAAGTPGYMAPE 530 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP--- 839 + G S D + +G +LEI G+ SP ++F RL + P Sbjct 531 YMELG--EFSMKSDVYSYGVLVLEIIC-GKRNTSFSSP--VQNFVTYVWRLWKSGTPLNL 585 Query 840 ---------------QLATLTSQCLTYEPTQRPSFRTILRD 865 + + C+ EPT RP F I+ Sbjct 586 VDATIAENYKSEEVIRCIHIALLCVQEEPTDRPDFSIIMSM 626 >sp|Q869W6|MYLKG_DICDI Probable myosin light chain kinase DDB_G0275057 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0275057 PE=3 SV=1 Length=349 Score = 222 bits (566), Expect = 3e-63, Method: Composition-based stats. Identities = 74/275 (27%), Positives = 109/275 (40%), Gaps = 31/275 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHII 960 +LG G F V + T T + VA+K + K +H ++EIDI++ + HE+++ Sbjct 61 ELGRGAFSVVR----EGTRKTTSDKVALKYIEKKFVKKKHIEQLRREIDIMKKVKHENVL 116 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLR-DYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 K E + L LVME V G L + R S +Q+C G+ YLH+Q Sbjct 117 SLKEIFE--SDSHLTLVMELVTGGELFYKIVERGSFTEKGARNVVRQVCAGVEYLHSQGI 174 Query 1020 IHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 HRDL N+L + D +KI DFGL+K G E + APE L Sbjct 175 AHRDLKPENLLCNGEGEDMTIKIADFGLSKIFGTGEAL----ETSCGTPDYVAPEVLTGG 230 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 + A D+WS GV Y LL L ++L P Sbjct 231 SYDNAVDMWSIGVITYILLCGFPPF--------------YASSQNLLFEKILTADYDFPE 276 Query 1137 PD--KCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 P+ ++N + R T + + L Sbjct 277 PEWTHVSEHAKAFIRNLIVKDPDQRHTAKQCLDDL 311 Score = 170 bits (430), Expect = 5e-45, Method: Composition-based stats. Identities = 65/343 (19%), Positives = 114/343 (33%), Gaps = 50/343 (15%) Query 543 DCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLS--------- 593 CF+ + +P T+ + T + +DQ +I+Q + Sbjct 2 GCFNSKEAGAGRPKTTTQQQQQATPEPTVTTAEVRADEKISMDQ-DISQGNVEDFYVVGK 60 Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDI 651 LG+G + V EG + +V LK ++ Sbjct 61 ELGRGAFSVVREGTRKTTSD------------------------KVALKYIEKKFVKKKH 96 Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711 +M +V H ++ + + +V E V G L + ERG Sbjct 97 IEQLRREIDIMKKVKHENVLSLKEIFESDSHLTLVMELVTGGELFYKI-VERGSFTEKGA 155 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---GALS 768 V +Q+ + + YL ++ + H ++ N+L EG IK++D G+ + Sbjct 156 RNVVRQVCAGVEYLHSQGIAHRDLKPENLLCN----GEGEDMTIKIADFGLSKIFGTGEA 211 Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 E ++APE L GG S A+D W G + S E Sbjct 212 LETSCGTPDYVAPEVLTGG--SYDNAVDMWSIGVITYILLCGFPPFYASSQNLLFEKILT 269 Query 829 RQHRLPEPSCPQLAT----LTSQCLTYEPTQRPSFRTILRDLT 867 + PEP ++ + +P QR + + L DL Sbjct 270 ADYDFPEPEWTHVSEHAKAFIRNLIVKDPDQRHTAKQCLDDLW 312 >sp|O64556|Y2923_ARATH Putative leucine-rich repeat receptor-like serine/threonine-protein kinase At2g19230 OS=Arabidopsis thaliana OX=3702 GN=At2g19230 PE=1 SV=3 Length=877 Score = 236 bits (601), Expect = 3e-63, Method: Composition-based stats. Identities = 66/313 (21%), Positives = 125/313 (40%), Gaps = 17/313 (5%) Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE 925 + + + + + R LG+G FGKV GE Sbjct 538 FWQFKKRQQSVKTGPLDTKRYYKYSEIVEITNNFERVLGQGGFGKVYYGVLR------GE 591 Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 VA+K L Q ++ E+++L ++H+++I G C + + + L+ EY+ G+ Sbjct 592 QVAIKMLSK-SSAQGYKEFRAEVELLLRVHHKNLIALIGYCHEGDQ--MALIYEYIGNGT 648 Query 986 LRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKI 1039 L DYL + + + L + +G+ YLH +HRD+ N+L++ KI Sbjct 649 LGDYLSGKNSSILSWEERLQISLDAAQGLEYLHNGCKPPIVHRDVKPTNILINEKLQAKI 708 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGL+++ + V + + + PE +F SDV+SFGV L E++T Sbjct 709 ADFGLSRSFTLEGDSQ-VSTEVAGTIGYLDPEHYSMQQFSEKSDVYSFGVVLLEVITGQP 767 Query 1100 S-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 S+S + + ++ + +++ ++ + C Sbjct 768 VISRSRTEENRHISDRVSLMLSKGDIKSIVDPKLGERFNAGLAWKITEVALACASESTKT 827 Query 1159 RPTFENLIPILKT 1171 R T ++ LK Sbjct 828 RLTMSQVVAELKE 840 Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats. Identities = 60/268 (22%), Positives = 96/268 (36%), Gaps = 47/268 (18%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 + + + LGQG VY G LR E Sbjct 557 RYYKYSEIVEITNNFERVLGQGGFGKVYYGVLRGE------------------------- 591 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +V +K+L S F L+ +V H +L + G C G + ++ EY+ +G L Sbjct 592 -QVAIKMLSKSSAQGYKEFRAEVELLLRVHHKNLIALIGYCHEGDQMALIYEYIGNGTLG 650 Query 697 VWLRRERGH-VPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTS 752 +L + + ++ ++ A L YL N +VH +V NIL+ A Sbjct 651 DYLSGKNSSILSWEERLQISLDAAQGLEYLHNGCKPPIVHRDVKPTNILINEKLQA---- 706 Query 753 PFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 K++D G+ + E I +L PE S D + FG LLE Sbjct 707 ---KIADFGLSRSFTLEGDSQVSTEVAGTIGYLDPEHYSM--QQFSEKSDVYSFGVVLLE 761 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLP 834 + P+ SRS +E+ + L Sbjct 762 VITG--QPVISRSRTEENRHISDRVSLM 787 >sp|Q9SXB3|Y1112_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g11280 OS=Arabidopsis thaliana OX=3702 GN=At1g11280 PE=2 SV=1 Length=820 Score = 235 bits (599), Expect = 3e-63, Method: Composition-based stats. Identities = 74/312 (24%), Positives = 123/312 (39%), Gaps = 27/312 (9%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 + LG+G FG V D +AVK L + G Q Sbjct 492 FFEMNTIRAATNNFNVSNKLGQGGFGPVYKGTLSDKKD-----IAVKRLSSSSG-QGTEE 545 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQ 999 + EI ++ L H ++++ GCC D EK L+ E++ SL +L + I + Sbjct 546 FMNEIKLISKLQHRNLVRLLGCCIDGEEK--LLIYEFLVNKSLDTFLFDLTLKLQIDWPK 603 Query 1000 LLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 Q + G+ YLH IHRDL N+LLD+ KI DFGLA+ +G ++ Sbjct 604 RFNIIQGVSRGLLYLHRDSCMRVIHRDLKVSNILLDDKMNPKISDFGLARMF-QGTQHQD 662 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIA 1115 + + +PE F SD+++FGV L E+++ SS + L+G A Sbjct 663 NTRKVVGTLGYMSPEYAWTGMFSEKSDIYAFGVLLLEIISGKKISSFCCGEEGKTLLGHA 722 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPC------EVYHLMKNCWETEASFRPTFENLIPIL 1169 +LL+ C + C + +A RP ++ ++ Sbjct 723 WECWLETGGVDLLDE----DISSSCSPVEVEVARCVQIGLLCIQQQAVDRPNIAQVVTMM 778 Query 1170 KTVHEKYQGQAP 1181 + + + + P Sbjct 779 TSATDLPRPKQP 790 Score = 222 bits (566), Expect = 5e-59, Method: Composition-based stats. Identities = 52/250 (21%), Positives = 93/250 (37%), Gaps = 45/250 (18%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L +++ R + LGQG VY+G L + Sbjct 490 LTFFEMNTIRAATNNFNVSNKLGQGGFGPVYKGTLSDKKD-------------------- 529 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + +K L S F L+S++ H +L + G C+ G E +++ E++ + Sbjct 530 -----IAVKRLSSSSGQGTEEFMNEIKLISKLQHRNLVRLLGCCIDGEEKLLIYEFLVNK 584 Query 694 PLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLA 748 LD +L + + W + + Q ++ L YL ++H ++ NILL Sbjct 585 SLDTFLFDLTLKLQIDWPKRFNIIQGVSRGLLYLHRDSCMRVIHRDLKVSNILLDDK--- 641 Query 749 EGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 K+SD G+ + + V + +++PE G S D + FG Sbjct 642 ----MNPKISDFGLARMFQGTQHQDNTRKVVGTLGYMSPEYAWTGM--FSEKSDIYAFGV 695 Query 803 TLLEICFDGE 812 LLEI + Sbjct 696 LLLEIISGKK 705 >sp|G5EBZ8|ARK1_CAEEL Ack-related non-receptor tyrosine kinase OS=Caenorhabditis elegans OX=6239 GN=ark-1 PE=2 SV=1 Length=1043 Score = 238 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 95/294 (32%), Positives = 151/294 (51%), Gaps = 23/294 (8%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 + +D V + ++LG+G FG V + + VAVK + +D S Sbjct 99 NQDDNDHHVIPIEKITLCKELGQGEFGSVWQAGWKNSAGSDVIQVAVKCVGSDKLLATSS 158 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLA 998 + QE I+ + HEH+++ G D K + LV E GSL + L R S + Sbjct 159 SFLQEAAIMTRMRHEHVVRLYGVVLDT--KKIMLVSELATCGSLLECLHKPALRDSFPVH 216 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV- 1057 L +A+QI GM+YL Q IHRDLAARNVL+ + +LVKI DFGL++++ G +YYR Sbjct 217 VLCDYAEQIAMGMSYLELQRLIHRDLAARNVLVFSPKLVKISDFGLSRSLGIGEDYYRSE 276 Query 1058 -REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 + P+ W APEC+ KF SDVW++GVT++E+ ++ + + Sbjct 277 FTPNLKLPIAWCAPECINFLKFTSKSDVWAYGVTIWEMFSYGE--------------MPW 322 Query 1117 GQMTVLRLTELLERGER-LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + ++ EL++R + L RP CP ++Y ++K W + RPTF +++ Sbjct 323 KGRSGAQILELVDRKKELLTRPKACPEDIYDMLKETWTHQVQDRPTFSDIVAKF 376 Score = 217 bits (553), Expect = 2e-56, Method: Composition-based stats. Identities = 69/338 (20%), Positives = 136/338 (40%), Gaps = 44/338 (13%) Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 + S N H + ++IT LGQG +V++ + D Sbjct 92 KTSNSVANQDDNDHHVIPIEKITLCKELGQGEFGSVWQAGWKNSAGSDV----------- 140 Query 628 VPGRDRGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 ++V +K + + +F + A++M+++ H H+ ++GV + + ++V Sbjct 141 ---------IQVAVKCVGSDKLLATSSSFLQEAAIMTRMRHEHVVRLYGVVLDTKKIMLV 191 Query 687 TEYVEHGPLDVWLRRE--RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 +E G L L + R P+ A+Q+A +SYLE + L+H ++ RN+L+ Sbjct 192 SELATCGSLLECLHKPALRDSFPVHVLCDYAEQIAMGMSYLELQRLIHRDLAARNVLV-- 249 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVER---------IPWLAPECLPGGANSLSTAM 795 + +K+SD G+ E+ I W APEC+ ++ Sbjct 250 -----FSPKLVKISDFGLSRSLGIGEDYYRSEFTPNLKLPIAWCAPECI--NFLKFTSKS 302 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL---PEPSCPQLATLTSQCLTYE 852 D W +G T+ E+ GE P + RS ++ R+ L P+ + + + T++ Sbjct 303 DVWAYGVTIWEMFSYGEMPWKGRSGAQILELVDRKKELLTRPKACPEDIYDMLKETWTHQ 362 Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 RP+F I+ + ++ V+ + Sbjct 363 VQDRPTFSDIVAKFPERRAQSVRAVVDCKDSAADHLHF 400 >sp|Q5JLS2|CIPKC_ORYSJ CBL-interacting protein kinase 12 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK12 PE=1 SV=1 Length=540 Score = 228 bits (582), Expect = 3e-63, Method: Composition-based stats. Identities = 64/268 (24%), Positives = 109/268 (41%), Gaps = 26/268 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960 LG+G F KV Y + T E VA+K L + + K+EI++LR + H +I+ Sbjct 52 LGQGSFAKV----YQARHLETDECVAIKVLDKEKAVKGGMVHLVKREINVLRRVRHPNIV 107 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + + + + VMEYV G L + + + + QQ+ + + HA+ Sbjct 108 QLFEVMASKTK--IYFVMEYVRGGELFSRVSKGRLREDTARRYFQQLVSAVDFCHARGVF 165 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 HRDL N+L+D + +K+ DFGLA + + +P + APE L+ + Sbjct 166 HRDLKPENLLVDENGDLKVSDFGLAAGPDQFDPDGLLHTFCGTPA-YVAPEVLRRRGYDG 224 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS GV L+ L+ ++ L + GE P Sbjct 225 AKADIWSCGVILFALMAGYLPFHD---------------HNIMVLYRKIYNGE-FRCPRW 268 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 + L+ + R T +I Sbjct 269 FSKDFTRLITRLLDANPKTRITVPEIIE 296 Score = 187 bits (475), Expect = 3e-49, Method: Composition-based stats. Identities = 53/308 (17%), Positives = 91/308 (30%), Gaps = 43/308 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + LGQG+ VY+ R V +KVLD Sbjct 45 KYELGRVLGQGSFAKVYQARHLETDEC------------------------VAIKVLDKE 80 Query 648 H---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + +++ +V H ++ + V + V EYV G L R +G Sbjct 81 KAVKGGMVHLVKREINVLRRVRHPNIVQLFEVMASKTKIYFVMEYVRGGELFS--RVSKG 138 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + QQL SA+ + + + H ++ N+L+ G +K+SD G+ Sbjct 139 RLREDTARRYFQQLVSAVDFCHARGVFHRDLKPENLLVDENGD-------LKVSDFGLAA 191 Query 765 GALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 G + ++APE L D W G L + Sbjct 192 GPDQFDPDGLLHTFCGTPAYVAPEVLRRRGYD-GAKADIWSCGVILFALMAGYLPFHDHN 250 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 Y + R P L ++ L P R + I+ + + Sbjct 251 IMVLYRKIYNGEFRCPRWFSKDFTRLITRLLDANPKTRITVPEIIESDWFKKGYKPVKFY 310 Query 879 TVNPDSPA 886 + Sbjct 311 IEDDKLYN 318 >sp|Q01974|ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 OS=Homo sapiens OX=9606 GN=ROR2 PE=1 SV=2 Length=943 Score = 236 bits (603), Expect = 3e-63, Method: Composition-based stats. Identities = 83/349 (24%), Positives = 140/349 (40%), Gaps = 39/349 (11%) Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899 L L C + + + + + + + + ++ Sbjct 420 CLFFLVCMCRNKQKASASTP----QRRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRF 475 Query 900 IRDLGEGHFGKVSLYCYDPTNDGTG-EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 + +LGE FGKV G + VA+K LK R ++ E + L H + Sbjct 476 MEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPN 535 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----------------RHSIGLAQLL 1001 ++ G ++ L ++ Y G L ++L + ++ + Sbjct 536 VVCLLGVVTK--DQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFV 593 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 QI GM YL + H +H+DLA RNVL+ + VKI D GL + V +YY++ + Sbjct 594 HLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVY-AADYYKLLGNS 652 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 P+ W APE + KF SD+WS+GV L+E+ ++ + Sbjct 653 LLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQ--------------PYCGYSN 698 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + E++ + LP PD CP VY LM CW S RP F+++ L+ Sbjct 699 QDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 747 Score = 229 bits (583), Expect = 1e-60, Method: Composition-based stats. Identities = 69/340 (20%), Positives = 125/340 (37%), Gaps = 61/340 (18%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 RR + P + + ++ Q + + + LG+ VY+G Sbjct 441 RRQLMASPSQDMEMPLIN---------QHKQAKLKEISLSAVRFMEELGEDRFGKVYKGH 491 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVS 666 L G+ Q V +K L D + + F A L +++ Sbjct 492 LFGPAPGE-------------------QTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQ 532 Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---------------RRERGHVPMAWK 711 H ++ + GV + M+ Y HG L +L R + + Sbjct 533 HPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDF 592 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE 771 + + Q+A+ + YL + ++VH ++ RN+L+ +K+SD G+ + + Sbjct 593 VHLVAQIAAGMEYLSSHHVVHKDLATRNVLV-------YDKLNVKISDLGLFREVYAADY 645 Query 772 R------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 + I W+APE + G S+ D W +G L E+ G P S + Sbjct 646 YKLLGNSLLPIRWMAPEAIMYGKFSID--SDIWSYGVVLWEVFSYGLQPYCGYSNQDVVE 703 Query 826 FYQRQHRLPEP-SCPQ-LATLTSQCLTYEPTQRPSFRTIL 863 + + LP P CP + L +C P++RP F+ I Sbjct 704 MIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIH 743 >sp|Q9CAL2|CRK3_ARATH Cysteine-rich receptor-like protein kinase 3 OS=Arabidopsis thaliana OX=3702 GN=CRK3 PE=2 SV=1 Length=646 Score = 231 bits (589), Expect = 3e-63, Method: Composition-based stats. Identities = 72/309 (23%), Positives = 121/309 (39%), Gaps = 18/309 (6%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 + + Y LG+G G V G+ VAVK L Q Sbjct 310 CFSYENLERATDYFSDKNKLGQGGSGSVYKGVL-----TNGKTVAVKRL-FFNTKQWVDH 363 Query 944 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQ 999 + E++++ + H++++K GC E LV EY+ SL DYL + A+ Sbjct 364 FFNEVNLISQVDHKNLVKLLGCSITGPES--LLVYEYIANQSLHDYLFVRKDVQPLNWAK 421 Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 EGMAYLH + IHRD+ N+LL++D +I DFGLA+ PE + Sbjct 422 RFKIILGTAEGMAYLHEESNLRIIHRDIKLSNILLEDDFTPRIADFGLARLFPEDKTHIS 481 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 G + + APE + K +DV+SFGV + E++T ++ ++ Sbjct 482 TAIAG--TLGYMAPEYVVRGKLTEKADVYSFGVLMIEVITGKRNNAF-VQDAGSILQSVW 538 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 + E ++ + + C + RP ++ ++K E + Sbjct 539 SLYRTSNVEEAVDPILGDNFNKIEASRLLQIGLLCVQAAFDQRPAMSVVVKMMKGSLEIH 598 Query 1177 QGQAPSVFS 1185 P + Sbjct 599 TPTQPPFLN 607 Score = 216 bits (551), Expect = 4e-58, Method: Composition-based stats. Identities = 59/328 (18%), Positives = 120/328 (37%), Gaps = 50/328 (15%) Query 499 SLRLRKFPIEQQDGAFVLEGWGR----SFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQ 554 +R + + + G + + +++ +L F L++ + Sbjct 231 GCYMRFSTQKFYNNSGNSTSDGNGGHNHLGVILAVTSSVVAFVLLVSAAGFLLKKRHAKK 290 Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 E L + A+ L S + R + + LGQG +VY+G L + Sbjct 291 QREKKQLGSL-FMLANKSNLCFSYENLER-ATDYFSDKNKLGQGGSGSVYKGVLTNGKT- 347 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 V +K L + F+ +L+SQV H +L + Sbjct 348 ------------------------VAVKRLFFNTKQWVDHFFNEVNLISQVDHKNLVKLL 383 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---N 729 G + GPE+++V EY+ + L +L + P+ W + + A ++YL + Sbjct 384 GCSITGPESLLVYEYIANQSLHDYLFVRKDVQPLNWAKRFKIILGTAEGMAYLHEESNLR 443 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECL 784 ++H ++ NILL +++D G+ + + + ++APE + Sbjct 444 IIHRDIKLSNILL-------EDDFTPRIADFGLARLFPEDKTHISTAIAGTLGYMAPEYV 496 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGE 812 G L+ D + FG ++E+ Sbjct 497 VRG--KLTEKADVYSFGVLMIEVITGKR 522 >sp|Q6P9R2|OXSR1_MOUSE Serine/threonine-protein kinase OSR1 OS=Mus musculus OX=10090 GN=Oxsr1 PE=1 SV=1 Length=527 Score = 228 bits (581), Expect = 3e-63, Method: Composition-based stats. Identities = 71/293 (24%), Positives = 121/293 (41%), Gaps = 30/293 (10%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 P ++ + +G G V P E VA+K + + +EI Sbjct 9 PWSINRDDYELQEVIGSGATAVVQAAYCAPKK----ERVAIKRINLEKCQTSMDELLKEI 64 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQ 999 + +H +I+ Y + E L LVM+ + GS+ D + + Sbjct 65 QAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEPT 122 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--V 1057 + +++ EG+ YLH IHRD+ A N+LL D V+I DFG++ + G + R V Sbjct 123 IATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKV 182 Query 1058 REDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQS-PPTK--FLELIG 1113 R+ W APE +++ + + +D+WSFG+T EL T PP K L L Sbjct 183 RKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQN 242 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 T ++ E+L++ + ++ C + + RPT L+ Sbjct 243 DPPSLETGVQDKEMLKKYGK---------SFRKMISLCLQKDPEKRPTAAELL 286 Score = 177 bits (449), Expect = 6e-46, Method: Composition-based stats. Identities = 53/315 (17%), Positives = 102/315 (32%), Gaps = 61/315 (19%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +++ + +G G V P ++R V + Sbjct 10 WSINRDDYELQEVIGSGATAVV-------------------QAAYCAPKKER-----VAI 45 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K ++ ++ + MSQ H ++ + V E +V + + G + ++ Sbjct 46 KRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIK 105 Query 701 R-------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 + G + + +++ L YL +H +V NILL G Sbjct 106 HIVAKGEHKSGVLDEPTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG------- 158 Query 754 FIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 ++++D GV + R+ V W+APE + D W FG T Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKADIWSFGITA 217 Query 805 LEICFDGEAPLQSRSPSEKEHFY-----------QRQHRLPEPSCPQLATLTSQCLTYEP 853 +E+ G AP P + + + + + S CL +P Sbjct 218 IELA-TGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDP 276 Query 854 TQRPSFRTILRDLTR 868 +RP+ +LR Sbjct 277 EKRPTAAELLRHKFF 291 >sp|Q66GN2|LRK64_ARATH Lectin-domain containing receptor kinase VI.4 OS=Arabidopsis thaliana OX=3702 GN=LECRK64 PE=2 SV=1 Length=691 Score = 232 bits (591), Expect = 4e-63, Method: Composition-based stats. Identities = 76/384 (20%), Positives = 136/384 (35%), Gaps = 29/384 (8%) Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRP 857 W F GE PL + + ++ L T Sbjct 270 WSFA-------SGGEHPLAAMLDISQLPPPPPNKAKKRGYNGKVIALIVALSTVISIMLV 322 Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL-GEGHFGKVSLYCY 916 + R+Q + + ++ ++ K + G G FG V Sbjct 323 LLFLFMMYKKRMQQEEILEDWEIDHPHRFRYRDLYKATEGFKENRVVGTGGFGIVYRGNI 382 Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976 ++D +AVK + + Q + EI+ L L H++++ +G C+ + + L L Sbjct 383 RSSSD----QIAVKKITPN-SMQGVREFVAEIESLGRLRHKNLVNLQGWCKHRND--LLL 435 Query 977 VMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAAR 1027 + +Y+P GSL L + A+ I G+ YLH + IHRD+ Sbjct 436 IYDYIPNGSLDSLLYSKPRRSGAVLSWNARFQIAKGIASGLLYLHEEWEQIVIHRDVKPS 495 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 NVL+D+D ++GDFGLA+ G + + APE + ASDV++F Sbjct 496 NVLIDSDMNPRLGDFGLARLYERGS--QSCTTVVVGTIGYMAPELARNGNSSSASDVFAF 553 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 GV L E+++ + S + + Q + ++ + + Sbjct 554 GVLLLEIVSGRKPTDSGTFFIADWVMELQAS---GEILSAIDPRLGSGYDEGEARLALAV 610 Query 1148 MKNCWETEASFRPTFENLIPILKT 1171 C + RP ++ L Sbjct 611 GLLCCHHKPESRPLMRMVLRYLNR 634 Score = 206 bits (523), Expect = 3e-54, Method: Composition-based stats. Identities = 60/306 (20%), Positives = 105/306 (34%), Gaps = 58/306 (19%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + + +G G VY G +R ++ +K + Sbjct 359 ATEGFKENRVVGTGGFGIVYRGNIRSSSD------------------------QIAVKKI 394 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL----R 700 P+ F + ++ H +L + G C + +++ +Y+ +G LD L R Sbjct 395 TPNSMQGVREFVAEIESLGRLRHKNLVNLQGWCKHRNDLLLIYDYIPNGSLDSLLYSKPR 454 Query 701 RERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 R + + +A+ +AS L YL + ++H +V N+L+ + +L Sbjct 455 RSGAVLSWNARFQIAKGIASGLLYLHEEWEQIVIHRDVKPSNVLID-------SDMNPRL 507 Query 758 SDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 D G+ V I ++APE G + S+A D + FG LLEI + Sbjct 508 GDFGLARLYERGSQSCTTVVVGTIGYMAPELARNGNS--SSASDVFAFGVLLLEIVSGRK 565 Query 813 A---------PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ----CLTYEPTQRPSF 859 + E RL A L C ++P RP Sbjct 566 PTDSGTFFIADWVMELQASGEILSAIDPRLGSGYDEGEARLALAVGLLCCHHKPESRPLM 625 Query 860 RTILRD 865 R +LR Sbjct 626 RMVLRY 631 >sp|Q7ZUQ3|STK3_DANRE Serine/threonine-protein kinase 3 OS=Danio rerio OX=7955 GN=stk3 PE=2 SV=1 Length=492 Score = 227 bits (578), Expect = 4e-63, Method: Composition-based stats. Identities = 64/268 (24%), Positives = 110/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V + + +G++VA+K + + Q +EI I++ +++K Sbjct 31 KLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQ---EIIKEISIMQQCDSPYVVK 83 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ + +G+ YLH Sbjct 84 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLKSTLKGLEYLHFMRK 141 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 142 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 198 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 199 CVADIWSLGITSIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEH 245 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 + +K C R T L+ Sbjct 246 WSDDFTDFVKKCLVKNPEQRATATQLLQ 273 Score = 201 bits (510), Expect = 3e-54, Method: Composition-based stats. Identities = 58/314 (18%), Positives = 101/314 (32%), Gaps = 44/314 (14%) Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 M + + LS+ S + ++ L LG+G+ +V++ + G Sbjct 1 MEHSVPKNKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQ---------- 50 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 V +K + + S+M Q ++ +G + + Sbjct 51 --------------VVAIKQVPVESD--LQEIIKEISIMQQCDSPYVVKYYGSYFKNTDL 94 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 +V EY G + +R + V + L YL +H ++ NILL Sbjct 95 WIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLKSTLKGLEYLHFMRKIHRDIKAGNILLN 154 Query 744 RLGLAEGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWG 799 G KL+D GV R + W+APE + + D W Sbjct 155 TEG-------HAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWS 205 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQ 855 G T +E+ +G+ P P R PE +CL P Q Sbjct 206 LGITSIEMA-EGKPPYADIHPMRAIFMIPTNPPPTFRKPEHWSDDFTDFVKKCLVKNPEQ 264 Query 856 RPSFRTILRDLTRL 869 R + +L+ + Sbjct 265 RATATQLLQHPFIV 278 >sp|Q9ZR79|LRK57_ARATH L-type lectin-domain containing receptor kinase V.7 OS=Arabidopsis thaliana OX=3702 GN=LECRK57 PE=2 SV=2 Length=659 Score = 231 bits (589), Expect = 4e-63, Method: Composition-based stats. Identities = 71/281 (25%), Positives = 120/281 (43%), Gaps = 20/281 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG+V Y G+ +AVK D Q S + EI + L H ++++ Sbjct 339 LGKGGFGQV----YKGMLPGSDAEIAVKRTSHD-SRQGMSEFLAEISTIGRLRHPNLVRL 393 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-------HSIGLAQLLLFAQQICEGMAYLH 1015 G C + +++L LV +++P GSL L R + Q + + + +LH Sbjct 394 LGYC--KHKENLYLVYDFMPNGSLDRCLTRSNTNENQERLTWEQRFKIIKDVATALLHLH 451 Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 + +HRD+ NVLLD+ ++GDFGLAK +G + R G + + APE Sbjct 452 QEWVQVIVHRDIKPANVLLDHGMNARLGDFGLAKLYDQGFDPQTSRVAG--TLGYIAPEL 509 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 L+ + ++DV++FG+ + E++ + L+ +L + E Sbjct 510 LRTGRATTSTDVYAFGLVMLEVVCGRRLIERRAAENEAVLVDWILELWESGKLFDAAEES 569 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 R + V L C RP ++ IL V Sbjct 570 IRQEQNRGEIELVLKLGLLCAHHTELIRPNMSAVLQILNGV 610 Score = 205 bits (521), Expect = 3e-54, Method: Composition-based stats. Identities = 49/261 (19%), Positives = 92/261 (35%), Gaps = 40/261 (15%) Query 579 LSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S+ + K + LG+G VY+G L G + Sbjct 321 FSYKELFNATKGFKEKQLLGKGGFGQVYKGML------------------------PGSD 356 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 + +K F S + ++ H +L + G C +V +++ +G LD Sbjct 357 AEIAVKRTSHDSRQGMSEFLAEISTIGRLRHPNLVRLLGYCKHKENLYLVYDFMPNGSLD 416 Query 697 VWLRR-----ERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLAR-LGL 747 L R + + + + + +A+AL +L + +VH ++ N+LL + Sbjct 417 RCLTRSNTNENQERLTWEQRFKIIKDVATALLHLHQEWVQVIVHRDIKPANVLLDHGMNA 476 Query 748 AEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 G KL D G + ++APE L G +T+ D + FG +LE+ Sbjct 477 RLGDFGLAKLYDQGF---DPQTSRVAGTLGYIAPELLRTGRA--TTSTDVYAFGLVMLEV 531 Query 808 CFDGEAPLQSRSPSEKEHFYQ 828 + + +E Sbjct 532 VCGRRLIERRAAENEAVLVDW 552 >sp|Q9FLJ8|Y5613_ARATH Probable receptor-like protein kinase At5g61350 OS=Arabidopsis thaliana OX=3702 GN=At5g61350 PE=2 SV=1 Length=842 Score = 235 bits (599), Expect = 4e-63, Method: Composition-based stats. Identities = 82/396 (21%), Positives = 140/396 (35%), Gaps = 38/396 (10%) Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859 G +L + + + S F L +++ + Sbjct 439 LGVVVLLVRWQRRPKDWQKQNS----FSSWLLPLHASHSSYISS-------KGGSTSRRM 487 Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919 ++ + + + G G FGKV + D Sbjct 488 SIFGSKKSKSNGFSSFFSNQGLGRYFPFTELQTATQNFDENAVCGVGGFGKVYIGEIDG- 546 Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979 G VA+K + Q + ++ EI +L L H H++ G C++ E + LV E Sbjct 547 ----GTQVAIKR-GSQSSEQGINEFQTEIQMLSKLRHRHLVSLIGFCDENKE--MILVYE 599 Query 980 YVPLGSLRDYLPRHS---------IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAAR 1027 Y+ G LRD+L + Q L G+ YLH Q IHRD+ Sbjct 600 YMSNGPLRDHLYGSKENDPNPIPTLSWKQRLEICIGSARGLHYLHTGAAQGIIHRDVKTT 659 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 N+LLD + + K+ DFGL+K P + V + PE + + SDV+SF Sbjct 660 NILLDENLVAKVSDFGLSKDAPMDEGH--VSTAVKGSFGYLDPEYFRRQQLTDKSDVYSF 717 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR---LTELLERGERLPRPDKCPCEV 1144 GV L+E+L C P E + +A+ M + R L ++++ + Sbjct 718 GVVLFEVL--CARPVINPQLPREQVNLAEYAMNLHRKGMLEKIIDPKIVGTISKGSLRKF 775 Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180 + C RP +++ L+ + + A Sbjct 776 VEAAEKCLAEYGVDRPGMGDVLWNLEYALQLQEASA 811 Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats. Identities = 56/292 (19%), Positives = 98/292 (34%), Gaps = 54/292 (18%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 + + + + + G G VY G + Sbjct 512 YFPFTELQTATQNFDENAVCGVGGFGKVYIGEIDGG------------------------ 547 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 +V +K S F ++S++ H HL + G C E I+V EY+ +GPL Sbjct 548 -TQVAIKRGSQSSEQGINEFQTEIQMLSKLRHRHLVSLIGFCDENKEMILVYEYMSNGPL 606 Query 696 DVWLRRERGH-------VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARL 745 L + + + ++ + A L YL + ++H +V NILL Sbjct 607 RDHLYGSKENDPNPIPTLSWKQRLEICIGSARGLHYLHTGAAQGIIHRDVKTTNILLDE- 665 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGF 800 + K+SD G+ A E V +L PE L+ D + F Sbjct 666 ------NLVAKVSDFGLSKDAPMDEGHVSTAVKGSFGYLDPEYFR--RQQLTDKSDVYSF 717 Query 801 GATLLEICFDG-----EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ 847 G L E+ + P + + +E R+ L + P++ S+ Sbjct 718 GVVLFEVLCARPVINPQLPREQVNLAEYAMNLHRKGMLEKIIDPKIVGTISK 769 >sp|O08679|MARK2_RAT Serine/threonine-protein kinase MARK2 OS=Rattus norvegicus OX=10116 GN=Mark2 PE=1 SV=1 Length=722 Score = 233 bits (593), Expect = 4e-63, Method: Composition-based stats. Identities = 84/326 (26%), Positives = 129/326 (40%), Gaps = 29/326 (9%) Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 S T PT + + +S S H + ++ +G Sbjct 1 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMLRGRNSATSADEQPHIGNYRLLKTIG 60 Query 905 EGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963 +G+F KV L + TG+ VAVK + K +E+ I++ L H +I+K Sbjct 61 KGNFAKVKL----ARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLF 116 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHR 1022 E EK+L LVMEY G + DYL H + + +QI + Y H + +HR Sbjct 117 EVIE--TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHR 174 Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YA 1081 DL A N+LLD D +KI DFG + G++ + + APE + K+ Sbjct 175 DLKAENLLLDADMNIKIADFGFSNEFTFGNKL----DTFCGSPPYAAPELFQGKKYDGPE 230 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 DVWS GV LY L++ + L E + RG + P Sbjct 231 VDVWSLGVILYTLVSGSLPFD---------------GQNLKELRERVLRG-KYRIPFYMS 274 Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167 + +L+K S R T E ++ Sbjct 275 TDCENLLKKFLILNPSKRGTLEQIMK 300 Score = 193 bits (490), Expect = 7e-50, Method: Composition-based stats. Identities = 60/355 (17%), Positives = 113/355 (32%), Gaps = 49/355 (14%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 +P SN++ R + S + + L +G+G V R + G Sbjct 27 KPSSKSNMLRGRNSATS---------ADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGK 77 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLA 671 V +K++D + + + + +M ++H ++ Sbjct 78 ------------------------EVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIV 113 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 + V +V EY G + +L G + +Q+ SA+ Y K +V Sbjct 114 KLFEVIETEKTLYLVMEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYCHQKFIV 172 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGA 788 H ++ N+LL IK++D G + P+ APE G Sbjct 173 HRDLKAENLLLD-------ADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKK 225 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQ 847 +D W G L + G P ++ E R +R+P L + Sbjct 226 YD-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 283 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902 L P++R + I++D H ++ P + + Sbjct 284 FLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYT 338 >sp|Q9LK03|PERK2_ARATH Proline-rich receptor-like protein kinase PERK2 OS=Arabidopsis thaliana OX=3702 GN=PERK2 PE=2 SV=3 Length=717 Score = 232 bits (592), Expect = 4e-63, Method: Composition-based stats. Identities = 72/279 (26%), Positives = 120/279 (43%), Gaps = 21/279 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V G+ VAVK LK + Q ++ E+ I+ ++H H++ Sbjct 360 LGQGGFGYVFKGMLR-----NGKEVAVKQLK-EGSSQGEREFQAEVGIISRVHHRHLVAL 413 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHAQ-- 1017 G C ++ LV E+VP +L +L R ++ + L A +G++YLH Sbjct 414 VGYCIADAQR--LLVYEFVPNNTLEFHLHGKGRPTMEWSSRLKIAVGSAKGLSYLHENCN 471 Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ A N+L+D K+ DFGLAK + + + R + APE Sbjct 472 PKIIHRDIKASNILIDFKFEAKVADFGLAKIASDTNTHVSTR--VMGTFGYLAPEYASSG 529 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMT----VLRLTELLERG 1131 K SDV+SFGV L EL+T + L+ A+ + + ++++ Sbjct 530 KLTEKSDVFSFGVVLLELITGRRPIDVNNVHADNSLVDWARPLLNQVSELGNFEVVVDKK 589 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + + C + A RP + + +L+ Sbjct 590 LNNEYDKEEMARMVACAAACVRSTAPRRPRMDQVARVLE 628 Score = 227 bits (578), Expect = 3e-61, Method: Composition-based stats. Identities = 64/293 (22%), Positives = 106/293 (36%), Gaps = 52/293 (18%) Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 P PG L I +G T N +LS ++ + LGQG V++G LR Sbjct 326 PPSPGLALGLGIYQG------TFNYEELS---RATNGFSEANLLGQGGFGYVFKGMLRNG 376 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 V +K L F ++S+V H HL Sbjct 377 K-------------------------EVAVKQLKEGSSQGEREFQAEVGIISRVHHRHLV 411 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVPMAWKMVVAQQLASALSYLENK-- 728 + G C+ + ++V E+V + L+ L + R + + ++ +A A LSYL Sbjct 412 ALVGYCIADAQRLLVYEFVPNNTLEFHLHGKGRPTMEWSSRLKIAVGSAKGLSYLHENCN 471 Query 729 -NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPE 782 ++H ++ NIL+ A K++D G+ A V +LAPE Sbjct 472 PKIIHRDIKASNILIDFKFEA-------KVADFGLAKIASDTNTHVSTRVMGTFGYLAPE 524 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 G L+ D + FG LLE+ + ++ + L + Sbjct 525 YASSG--KLTEKSDVFSFGVVLLELITGRRPIDVNNVHADNSLVDWARPLLNQ 575 >sp|Q10925|SID3_CAEEL Tyrosine-protein kinase sid-3 OS=Caenorhabditis elegans OX=6239 GN=sid-3 PE=1 SV=2 Length=1237 Score = 239 bits (609), Expect = 4e-63, Method: Composition-based stats. Identities = 88/315 (28%), Positives = 142/315 (45%), Gaps = 24/315 (8%) Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918 + + + + + ++ + + + +K +GEG F V + Sbjct 69 MSREMWNRSDPKQVYIQADQSMPAQNSIDEKALIPNEQIKLYELIGEGSFAVVKRGTWTQ 128 Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978 +N GT VAVK L+ D P + E L L H +I+ G +V Sbjct 129 SN-GTHVNVAVKILR-DISPNIMDDLRVEASHLLKLQHPSLIRLYGIVRQPA----MMVF 182 Query 979 EYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND- 1034 E GSL D L + +++L + QI + + +L ++H +HRD+AARN+LL D Sbjct 183 ELCEGGSLLDRLRDDKKAILLVSRLHDYCMQIAKALQFLESKHCVHRDVAARNILLARDE 242 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 R VKI DFGL +A+ E + Y + P W PE L+ KF +ASDVWS+GVT++E+ Sbjct 243 RTVKICDFGLMRALKENEQMYTMAPQKKVPFAWCPPEALRHRKFSHASDVWSYGVTIWEV 302 Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154 T + + + + ++ GERL +P C +Y +MKNCW+ Sbjct 303 FTFGEE--------------PWVGCRAIDVLKNIDAGERLEKPKYCSERIYQIMKNCWKF 348 Query 1155 EASFRPTFENLIPIL 1169 + R F + L Sbjct 349 NPAERCKFGAIREDL 363 Score = 223 bits (567), Expect = 5e-58, Method: Composition-based stats. Identities = 66/290 (23%), Positives = 110/290 (38%), Gaps = 41/290 (14%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + ++I +G+G+ V G + G + V +K+ Sbjct 102 IPNEQIKLYELIGEGSFAVVKRGTW---------------------TQSNGTHVNVAVKI 140 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 L +I AS + ++ H L ++G+ + +MV E E G L LR ++ Sbjct 141 LRDISPNIMDDLRVEASHLLKLQHPSLIRLYGIVRQ--PAMMVFELCEGGSLLDRLRDDK 198 Query 704 GHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + + ++ Q+A AL +LE+K+ VH +V RNILLAR +K+ D G+ Sbjct 199 KAILLVSRLHDYCMQIAKALQFLESKHCVHRDVAARNILLAR------DERTVKICDFGL 252 Query 763 GLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 E+ W PE L S A D W +G T+ E+ GE P Sbjct 253 MRALKENEQMYTMAPQKKVPFAWCPPEALRH--RKFSHASDVWSYGVTIWEVFTFGEEPW 310 Query 816 QSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 + RL P+ ++ + C + P +R F I Sbjct 311 VGCRAIDVLKNIDAGERLEKPKYCSERIYQIMKNCWKFNPAERCKFGAIR 360 >sp|A0A8I5ZNK2|OXSR1_RAT Serine/threonine-protein kinase OSR1 OS=Rattus norvegicus OX=10116 GN=Oxsr1 PE=1 SV=1 Length=528 Score = 228 bits (580), Expect = 4e-63, Method: Composition-based stats. Identities = 71/293 (24%), Positives = 122/293 (42%), Gaps = 30/293 (10%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 P ++ + +G G V P E VA+K + + +EI Sbjct 9 PWSINRDDYELQEVIGSGATAVVQAAYCAPKK----ERVAIKRINLEKCQTSMDELLKEI 64 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQ 999 + +H +I+ Y + E L LVM+ + GS+ D + + + Sbjct 65 QAMSQCHHPNIVSYYTSFVVKDE--LWLVMKLLSGGSVLDIIKHIVAKGEHKGGVLDEST 122 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--V 1057 + +++ EG+ YLH IHRD+ A N+LL D V+I DFG++ + G + R V Sbjct 123 IATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKV 182 Query 1058 REDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQS-PPTK--FLELIG 1113 R+ W APE +++ + + +D+WSFG+T EL T PP K L L Sbjct 183 RKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQN 242 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 T ++ E+L++ + ++ C + + RPT L+ Sbjct 243 DPPSLDTGVQDKEMLKKYGK---------SFRKMISLCLQKDPEKRPTAAELL 286 Score = 177 bits (449), Expect = 7e-46, Method: Composition-based stats. Identities = 53/315 (17%), Positives = 103/315 (33%), Gaps = 61/315 (19%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +++ + +G G V P ++R V + Sbjct 10 WSINRDDYELQEVIGSGATAVV-------------------QAAYCAPKKER-----VAI 45 Query 642 KVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K ++ ++ + MSQ H ++ + V E +V + + G + ++ Sbjct 46 KRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIK 105 Query 701 R-------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 + G + + + +++ L YL +H +V NILL G Sbjct 106 HIVAKGEHKGGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDG------- 158 Query 754 FIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 ++++D GV + R+ V W+APE + D W FG T Sbjct 159 SVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKADIWSFGITA 217 Query 805 LEICFDGEAPLQSRSPSEKEHFY-----------QRQHRLPEPSCPQLATLTSQCLTYEP 853 +E+ G AP P + + + + + S CL +P Sbjct 218 IELA-TGAAPYHKYPPMKVLMLTLQNDPPSLDTGVQDKEMLKKYGKSFRKMISLCLQKDP 276 Query 854 TQRPSFRTILRDLTR 868 +RP+ +LR Sbjct 277 EKRPTAAELLRHKFF 291 >sp|Q9FIZ3|GSO2_ARATH LRR receptor-like serine/threonine-protein kinase GSO2 OS=Arabidopsis thaliana OX=3702 GN=GSO2 PE=1 SV=2 Length=1252 Score = 239 bits (609), Expect = 5e-63, Method: Composition-based stats. Identities = 71/300 (24%), Positives = 125/300 (42%), Gaps = 22/300 (7%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 D + YL + +G G GKV GE +AVK + + + Sbjct 938 WDDIMEATHYLNEEFMIGSGGSGKVYKAELK-----NGETIAVKKILWKDDLMSNKSFNR 992 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-------PRHSIGLAQ 999 E+ L T+ H H++K G C + + L+ EY+ GS+ D+L + +G Sbjct 993 EVKTLGTIRHRHLVKLMGYCSSKADGLNLLIYEYMANGSVWDWLHANENTKKKEVLGWET 1052 Query 1000 LLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 L A + +G+ YLH +HRD+ + NVLLD++ +GDFGLAK + ++ Sbjct 1053 RLKIALGLAQGVEYLHYDCVPPIVHRDIKSSNVLLDSNIEAHLGDFGLAKILTGNYDTNT 1112 Query 1057 -VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 + APE K SDV+S G+ L E++T +++ + +++ Sbjct 1113 ESNTMFAGSYGYIAPEYAYSLKATEKSDVYSMGIVLMEIVTGKMPTEAMFDEETDMVRWV 1172 Query 1116 QGQMTVLRLTELLER------GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + + +E E+ LP ++ +V + C ++ RP+ L Sbjct 1173 ETVLDTPPGSEAREKLIDSELKSLLPCEEEAAYQVLEIALQCTKSYPQERPSSRQASEYL 1232 Score = 176 bits (446), Expect = 2e-43, Method: Composition-based stats. Identities = 47/272 (17%), Positives = 94/272 (35%), Gaps = 54/272 (20%) Query 577 SQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 S + + + + + +G G VY+ L+ G Sbjct 934 SDIKWDDIMEATHYLNEEFMIGSGGSGKVYKAELK-----------------------NG 970 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEH 692 + + V K+L +F + + H HL + G C + N+++ EY+ + Sbjct 971 ETIAVK-KILWKDDLMSNKSFNREVKTLGTIRHRHLVKLMGYCSSKADGLNLLIYEYMAN 1029 Query 693 GPLDVWLR-----RERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744 G + WL +++ + ++ +A LA + YL +VH ++ N+LL Sbjct 1030 GSVWDWLHANENTKKKEVLGWETRLKIALGLAQGVEYLHYDCVPPIVHRDIKSSNVLLD- 1088 Query 745 LGLAEGTSPFIKLSDPGVGL--------GALSREERVERIPWLAPECLPGGANSLSTAMD 796 ++ L D G+ S ++APE + + D Sbjct 1089 ------SNIEAHLGDFGLAKILTGNYDTNTESNTMFAGSYGYIAPEYA--YSLKATEKSD 1140 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 + G L+EI G+ P ++ E + Sbjct 1141 VYSMGIVLMEIV-TGKMPTEAMFDEETDMVRW 1171 >sp|Q9XID3|Y1343_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At1g34300 OS=Arabidopsis thaliana OX=3702 GN=At1g34300 PE=1 SV=1 Length=829 Score = 234 bits (598), Expect = 5e-63, Method: Composition-based stats. Identities = 69/356 (19%), Positives = 126/356 (35%), Gaps = 40/356 (11%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 L C P + + + + L Sbjct 443 LWWCCCRKNPRFGTLSS------------HYTLLEYASGAPVQFTYKELQRCTKSFKEKL 490 Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963 G G FG V +VAVK L + Q ++ E+ + + +H ++++ Sbjct 491 GAGGFGTVYRGVLTNR-----TVVAVKQL--EGIEQGEKQFRMEVATISSTHHLNLVRLI 543 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018 G C + LV E++ GSL ++L + A +G+ YLH + Sbjct 544 GFCSQGRHR--LLVYEFMRNGSLDNFLFTTDSAKFLTWEYRFNIALGTAKGITYLHEECR 601 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +H D+ N+L+D++ K+ DFGLAK + Y + + APE L Sbjct 602 DCIVHCDIKPENILVDDNFAAKVSDFGLAKLLNPKDNRYNM-SSVRGTRGYLAPEWLANL 660 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 SDV+S+G+ L EL++ + S T + A + +L+ Sbjct 661 PITSKSDVYSYGMVLLELVSGKRNFDVSEKTNHKKFSIWAYEEFEKGNTKAILDTRL--- 717 Query 1136 RPDKCPCEVYHLMKN------CWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 + ++ +M+ C + + RPT ++ +L+ + E P S Sbjct 718 -SEDQTVDMEQVMRMVKTSFWCIQEQPLQRPTMGKVVQMLEGITEIKNPLCPKTIS 772 Score = 205 bits (521), Expect = 3e-53, Method: Composition-based stats. Identities = 63/353 (18%), Positives = 121/353 (34%), Gaps = 73/353 (21%) Query 550 CCLPQPG---ETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606 CC P +S+ ++ A +P Q ++ + + + LG G VY G Sbjct 447 CCRKNPRFGTLSSHYTLLEYASGAPV-----QFTYKELQRCTKSFKEKLGAGGFGTVYRG 501 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS 666 L V +K L F + +S Sbjct 502 VL-------------------------TNRTVVAVKQL-EGIEQGEKQFRMEVATISSTH 535 Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--RERGHVPMAWKMVVAQQLASALSY 724 H +L + G C +G ++V E++ +G LD +L + ++ +A A ++Y Sbjct 536 HLNLVRLIGFCSQGRHRLLVYEFMRNGSLDNFLFTTDSAKFLTWEYRFNIALGTAKGITY 595 Query 725 LEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVER 775 L +VH ++ NIL+ + K+SD G+ + Sbjct 596 LHEECRDCIVHCDIKPENILVD-------DNFAAKVSDFGLAKLLNPKDNRYNMSSVRGT 648 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE-APLQSRSPSEKEHFYQRQH--- 831 +LAPE L +++ D + +G LLE+ + ++ +K + + Sbjct 649 RGYLAPEWLAN--LPITSKSDVYSYGMVLLELVSGKRNFDVSEKTNHKKFSIWAYEEFEK 706 Query 832 ---------RLPEPSCPQLATLTSQ------CLTYEPTQRPSFRTILRDLTRL 869 RL E + + C+ +P QRP+ +++ L + Sbjct 707 GNTKAILDTRLSEDQTVDMEQVMRMVKTSFWCIQEQPLQRPTMGKVVQMLEGI 759 >sp|Q5XF57|Y5576_ARATH Probable receptor-like serine/threonine-protein kinase At5g57670 OS=Arabidopsis thaliana OX=3702 GN=At5g57670 PE=2 SV=1 Length=579 Score = 229 bits (583), Expect = 5e-63, Method: Composition-based stats. Identities = 68/306 (22%), Positives = 121/306 (40%), Gaps = 19/306 (6%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935 + + +G G + +V + G +AVK L + Sbjct 246 PKPQPLIQCFTYNEISKATNDFHQGNIVGIGGYSEVYRG-----DLWDGRRIAVKRLAKE 300 Query 936 CGPQHRS-GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993 G ++ + E+ I+ + H + GCC ++G L LV + G+L L + Sbjct 301 SGDMNKEKEFLTELGIISHVSHPNTALLLGCCVEKG---LYLVFRFSENGTLYSALHENE 357 Query 994 --SIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 S+ A + G+ YLH IHRD+ + NVLL D +I DFGLAK + Sbjct 358 NGSLDWPVRYKIAVGVARGLHYLHKRCNHRIIHRDIKSSNVLLGPDYEPQITDFGLAKWL 417 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 P ++ V + + APE L + +D+++FG+ L E++T Sbjct 418 PNKWTHHAV-IPVEGTFGYLAPESLMQGTIDEKTDIYAFGILLLEIITGRRPVNPTQKHI 476 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 L A+ M +EL++ + D+ ++ +C + RPT ++ + Sbjct 477 LL---WAKPAMETGNTSELVDPKLQDKYDDQQMNKLVLTASHCVQQSPILRPTMTQVLEL 533 Query 1169 LKTVHE 1174 L +E Sbjct 534 LTNGNE 539 Score = 182 bits (461), Expect = 4e-47, Method: Composition-based stats. Identities = 70/366 (19%), Positives = 121/366 (33%), Gaps = 63/366 (17%) Query 566 GARASPRTLNLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 + P+ L + +++ + + Q + +G G + VY G L Sbjct 243 KNKPKPQPL-IQCFTYNEISKATNDFHQGNIVGIGGYSEVYRGDLWDGR----------- 290 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDI--ALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 R+ +K L D+ F ++S VSH + A + G CV Sbjct 291 --------------RIAVKRLAKESGDMNKEKEFLTELGIISHVSHPNTALLLGCCVEKG 336 Query 682 ENIMVTEYVEHGPLDVWLR-RERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCG 737 +V + E+G L L E G + + +A +A L YL N ++H ++ Sbjct 337 -LYLVFRFSENGTLYSALHENENGSLDWPVRYKIAVGVARGLHYLHKRCNHRIIHRDIKS 395 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV------ERIPWLAPECLPGGANSL 791 N+LL G +++D G+ ++ +LAPE L G ++ Sbjct 396 SNVLL-------GPDYEPQITDFGLAKWLPNKWTHHAVIPVEGTFGYLAPESLMQG--TI 446 Query 792 STAMDKWGFGATLLEICFDGEA-------------PLQSRSPSEKEHFYQRQHRLPEPSC 838 D + FG LLEI P + + + Q + + Sbjct 447 DEKTDIYAFGILLLEIITGRRPVNPTQKHILLWAKPAMETGNTSELVDPKLQDKYDDQQM 506 Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898 +L S C+ P RP+ +L LT +A + D D Sbjct 507 NKLVLTASHCVQQSPILRPTMTQVLELLTNGNEAEIAKSWRMPKDMTNDDDDNNEWDDYS 566 Query 899 KIRDLG 904 I Sbjct 567 MIFGYD 572 >sp|P50527|STE20_SCHPO Serine/threonine-protein kinase shk1/pak1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=shk1 PE=1 SV=2 Length=658 Score = 231 bits (588), Expect = 5e-63, Method: Composition-based stats. Identities = 61/277 (22%), Positives = 115/277 (42%), Gaps = 25/277 (9%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 + +G+G G V Y GT VA+K + + P+ + EI ++++ +H Sbjct 386 YRNFVKIGQGASGDV----YSARQVGTNLSVAIKKMNINQQPK-KEFIVNEILVMKSHHH 440 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016 ++I+ + + E L +VMEY+ GSL + + +++ Q+ ++ EG+ +LH Sbjct 441 KNIVNFIDTFFYKSE--LWMVMEYMRGGSLTEVVTNNTLSEGQIAAICKETLEGLQHLHE 498 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRD+ + N+LL +K+ DFG + R +W APE + Sbjct 499 NGIVHRDIKSDNILLSLQGDIKLTDFGFCAQIDSNM---TKRTTMVGTPYWMAPEVVTRK 555 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 ++ + DVWS G+ E++ PP + T+ ++ R Sbjct 556 EYGFKVDVWSLGIMAIEMV-----EGEPPYLNENPLRALYLIATIGT--------PKISR 602 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKT 1171 P+ + + RP+ L+ P LK Sbjct 603 PELLSSVFHDFLSKSLTVNPKQRPSSGELLRHPFLKQ 639 Score = 189 bits (480), Expect = 5e-49, Method: Composition-based stats. Identities = 60/282 (21%), Positives = 92/282 (33%), Gaps = 44/282 (16%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 +GQG +VY R G L V +K ++ + Sbjct 391 KIGQGASGDVYSA------------------------RQVGTNLSVAIKKMNINQQPKKE 426 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 +M H ++ E MV EY+ G L + + Sbjct 427 FIVNEILVMKSHHHKNIVNFIDTFFYKSELWMVMEYMRGGSLTEVVTNN--TLSEGQIAA 484 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----R 769 + ++ L +L +VH ++ NILL+ G IKL+D G S R Sbjct 485 ICKETLEGLQHLHENGIVHRDIKSDNILLSLQGD-------IKLTDFGFCAQIDSNMTKR 537 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 V W+APE + +D W G +E+ +GE P + +P + Sbjct 538 TTMVGTPYWMAPEVVTRKEYGF--KVDVWSLGIMAIEMV-EGEPPYLNENPLRALYLIAT 594 Query 830 QHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 PE S+ LT P QRPS +LR Sbjct 595 IGTPKISRPELLSSVFHDFLSKSLTVNPKQRPSSGELLRHPF 636 >sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens OX=9606 GN=MAP3K3 PE=1 SV=2 Length=626 Score = 230 bits (586), Expect = 5e-63, Method: Composition-based stats. Identities = 78/279 (28%), Positives = 131/279 (47%), Gaps = 24/279 (9%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP----QHRSGWKQEID 949 ++ + LG+G FG+V L + TG +A K ++ D + S + EI Sbjct 359 PINWRRGKLLGQGAFGRVYLCY----DVDTGRELASKQVQFDPDSPETSKEVSALECEIQ 414 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQIC 1008 +L+ L HE I++Y GC D+ EK+L + MEY+P GS++D L + + + + +QI Sbjct 415 LLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQIL 474 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 EGM+YLH+ +HRD+ N+L D+ VK+GDFG +K + +W Sbjct 475 EGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWM 534 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 +PE + + +DVWS G T+ E+LT + PP E + + ++ Sbjct 535 SPEVISGEGYGRKADVWSLGCTVVEMLT-----EKPPWAEYEAMA---------AIFKIA 580 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + P ++ + EA RP+ E L+ Sbjct 581 TQPTNPQLPSHISEHGRDFLRRIF-VEARQRPSAEELLT 618 Score = 172 bits (436), Expect = 1e-43, Method: Composition-based stats. Identities = 61/373 (16%), Positives = 115/373 (31%), Gaps = 68/373 (18%) Query 478 SHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCL 537 ++P R ++V + + R+R+ Q F L RS + G Sbjct 274 TYPRRYHVSVHHKDYSDGRRTFPRIRR----HQGNLFTLVPSSRSLST--------NGEN 321 Query 538 LRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQ 597 + R + ++ N + ++ ++ + + LGQ Sbjct 322 MGLAVQYLDPRGRL--RSADSENALSVQERNVPTKSPSAPI---------NWRRGKLLGQ 370 Query 598 GTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE 657 G VY L D G+EL DP + + Sbjct 371 GAFGRVY----------------------LCYDVDTGRELASKQVQFDPDSPETSKEVSA 408 Query 658 ---TASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 L+ + H + +G E + EY+ G + L+ G + + Sbjct 409 LECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKA-YGALTESVTR 467 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-------VGLG 765 +Q+ +SYL + +VH ++ G NIL ++ +KL D G + + Sbjct 468 KYTRQILEGMSYLHSNMIVHRDIKGANIL-------RDSAGNVKLGDFGASKRLQTICMS 520 Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 W++PE + G D W G T++E+ + + P Sbjct 521 GTGMRSVTGTPYWMSPEVISG--EGYGRKADVWSLGCTVVEMLTE-KPPWAEYEAMAAIF 577 Query 826 FYQRQHRLPEPSC 838 Q P+ Sbjct 578 KIATQPTNPQLPS 590 >sp|Q9LK43|TMK4_ARATH Receptor-like kinase TMK4 OS=Arabidopsis thaliana OX=3702 GN=TMK4 PE=1 SV=1 Length=928 Score = 236 bits (601), Expect = 5e-63, Method: Composition-based stats. Identities = 82/292 (28%), Positives = 132/292 (45%), Gaps = 26/292 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG G FG V +DGT AVK ++ A G + S ++ EI +L + H H++ Sbjct 584 LGRGGFGVVYAGEL---HDGTKT--AVKRMECAAMGNKGMSEFQAEIAVLTKVRHRHLVA 638 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR------HSIGLAQLLLFAQQICEGMAYLH 1015 G C + E+ LV EY+P G+L +L + Q + A + G+ YLH Sbjct 639 LLGYCVNGNER--LLVYEYMPQGNLGQHLFEWSELGYSPLTWKQRVSIALDVARGVEYLH 696 Query 1016 A---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 + Q +IHRDL N+LL +D K+ DFGL K P+G Y V + APE Sbjct 697 SLAQQSFIHRDLKPSNILLGDDMRAKVADFGLVKNAPDGK--YSVETRLAGTFGYLAPEY 754 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLR-LTELLER 1130 + DV++FGV L E+LT + S P + L+ + + + + L++ Sbjct 755 AATGRVTTKVDVYAFGVVLMEILTGRKALDDSLPDERSHLVTWFRRILINKENIPKALDQ 814 Query 1131 GERLPRPDKCPCEVYHLMKN---CWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L ++ +Y + + C E RP + + +L + EK++ Sbjct 815 --TLEADEETMESIYRVAELAGHCTAREPQQRPDMGHAVNVLGPLVEKWKPS 864 Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats. Identities = 76/348 (22%), Positives = 129/348 (37%), Gaps = 75/348 (22%) Query 546 SLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605 + P G+ S+ ++ G + L Q+ ++ + LG+G VY Sbjct 541 NFNALNSPSSGDNSDRFLLEGGSVTIPMEVLRQV------TNNFSEDNILGRGGFGVVYA 594 Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMS 663 G L + +K ++ + + F ++++ Sbjct 595 GELHDG-------------------------TKTAVKRMECAAMGNKGMSEFQAEIAVLT 629 Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--RERGHVPMAW--KMVVAQQLA 719 +V H HL + G CV G E ++V EY+ G L L E G+ P+ W ++ +A +A Sbjct 630 KVRHRHLVALLGYCVNGNERLLVYEYMPQGNLGQHLFEWSELGYSPLTWKQRVSIALDVA 689 Query 720 SALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV--- 773 + YL + ++ +H ++ NILL G K++D G+ A + V Sbjct 690 RGVEYLHSLAQQSFIHRDLKPSNILL-------GDDMRAKVADFGLVKNAPDGKYSVETR 742 Query 774 --ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 +LAPE G ++T +D + FG L+EI G L P E+ H Sbjct 743 LAGTFGYLAPEYAATG--RVTTKVDVYAFGVVLMEIL-TGRKALDDSLPDERSHLVTWFR 799 Query 832 RL--------------------PEPSCPQLATLTSQCLTYEPTQRPSF 859 R+ S ++A L C EP QRP Sbjct 800 RILINKENIPKALDQTLEADEETMESIYRVAELAGHCTAREPQQRPDM 847 >sp|Q9C9L5|WAKLH_ARATH Wall-associated receptor kinase-like 9 OS=Arabidopsis thaliana OX=3702 GN=WAKL9 PE=2 SV=1 Length=792 Score = 234 bits (596), Expect = 5e-63, Method: Composition-based stats. Identities = 71/280 (25%), Positives = 114/280 (41%), Gaps = 19/280 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G G V G +VAVK K + E+ IL + H +I+K Sbjct 453 LGQGGQGTVYKGML-----VDGRIVAVKKSKV-VDEDKLEEFINEVVILSQINHRNIVKL 506 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHAQ 1017 GCC + K LV E++P G+L ++L L A I ++YLH+ Sbjct 507 LGCCLET--KVPVLVYEFIPNGNLFEHLHDEFDENIMATWNIRLRIAIDIAGALSYLHSS 564 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 HRD+ + N++LD K+ DFG ++ V H + + V + PE + Sbjct 565 ASSPIYHRDVKSTNIMLDEKYRAKVSDFGTSRTVTVDHTH--LTTVVSGTVGYMDPEYFQ 622 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +F SDV+SFGV L EL+T S S + L M +L ++++ R Sbjct 623 SSQFTDKSDVYSFGVVLVELITGEKSISFLRSQENRTLATYFILAMKENKLFDIIDARIR 682 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + + C + RP+ + L ++ Sbjct 683 DGCMLSQVTATAKVARKCLNLKGRKRPSMREVSMELDSIR 722 Score = 223 bits (567), Expect = 2e-59, Method: Composition-based stats. Identities = 71/405 (18%), Positives = 131/405 (32%), Gaps = 68/405 (17%) Query 504 KFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGE---TSN 560 F + + G G SF S+ + + ++ + G Sbjct 362 HFKCVYNNHRPLAIGLGASFGSLIFVVGIYLLYKFIKKQRKLNQKKKFFKRNGGLLLQQQ 421 Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620 LI G + +L + + LGQG + VY+G L Sbjct 422 LISTVGMVEKTIVFSSRELEK---ATENFSSNRILGQGGQGTVYKGMLVDGRI------- 471 Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680 V +K D F ++SQ++H ++ + G C+ Sbjct 472 ------------------VAVKKSKVVDEDKLEEFINEVVILSQINHRNIVKLLGCCLET 513 Query 681 PENIMVTEYVEHGPLDVWLRRERGH---VPMAWKMVVAQQLASALSYLE---NKNLVHGN 734 ++V E++ +G L L E ++ +A +A ALSYL + + H + Sbjct 514 KVPVLVYEFIPNGNLFEHLHDEFDENIMATWNIRLRIAIDIAGALSYLHSSASSPIYHRD 573 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGAN 789 V NI+L A K+SD G + + ++ PE ++ Sbjct 574 VKSTNIMLDEKYRA-------KVSDFGTSRTVTVDHTHLTTVVSGTVGYMDPEYFQ--SS 624 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRS-------------PSEKEHFYQRQHRLPEP 836 + D + FG L+E+ ++ RS E + F R+ + Sbjct 625 QFTDKSDVYSFGVVLVELITGEKSISFLRSQENRTLATYFILAMKENKLFDIIDARIRDG 684 Query 837 SC----PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 A + +CL + +RPS R + +L ++ Sbjct 685 CMLSQVTATAKVARKCLNLKGRKRPSMREVSMELDSIRMPCGDMQ 729 >sp|P43450|CDK2_CARAU Cyclin-dependent kinase 2 OS=Carassius auratus OX=7957 GN=cdk2 PE=1 SV=1 Length=298 Score = 220 bits (560), Expect = 5e-63, Method: Composition-based stats. Identities = 67/291 (23%), Positives = 120/291 (41%), Gaps = 28/291 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y N TGE VA+K ++ D + S +EI +L+ Sbjct 1 MESFQKVEKIGEGTYGVV----YKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICE 1009 L H +I+K E L LV E++ L+ ++ + I L + + Q+ + Sbjct 57 ELNHPNIVKLHDVI--HTENKLYLVFEFLHQ-DLKRFMDSSTVTGISLPLVKSYLFQLLQ 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 G+A+ H+ +HRDL +N+L++ +K+ DFGLA+A R +++ A Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINAQGEIKLADFGLARAFGVP---VRTYTHEVVTLWYRA 170 Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQGQMTVLRLTE 1126 PE L K+Y A D+WS G E++T S + + + Sbjct 171 PEILLGCKYYSTAVDIWSLGCIFAEMITRKALFPGDSEIDQLFRIFRTLGTPDESIWPGV 230 Query 1127 LLERGERLPRPDKCPCEV-----------YHLMKNCWETEASFRPTFENLI 1166 + P ++ L+ + + R + +N + Sbjct 231 TSMPDYKPSFPKWARQDLSKVVPPLDEDGRDLLGQMLIYDPNKRISAKNAL 281 Score = 169 bits (427), Expect = 3e-45, Method: Composition-based stats. Identities = 48/266 (18%), Positives = 95/266 (36%), Gaps = 40/266 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 + ++ +G+GT VY+ + +V G V LK Sbjct 1 MESFQKVEKIGEGTYGVVYKAKNKVTGE------------------------TVALKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 LD + SL+ +++H ++ +H V + +V E++ H L ++ Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLHDVIHTENKLYLVFEFL-HQDLKRFMDSST 95 Query 704 -GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + + QL L++ + ++H ++ +N+L+ G IKL+D G+ Sbjct 96 VTGISLPLVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAQGE-------IKLADFGL 148 Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + + APE L G STA+D W G E+ Sbjct 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKY-YSTAVDIWSLGCIFAEMITRKALFPGDS 207 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ E P + ++ Sbjct 208 EIDQLFRIFRTLGTPDESIWPGVTSM 233 >sp|Q9ZNQ8|PERK4_ARATH Proline-rich receptor-like protein kinase PERK4 OS=Arabidopsis thaliana OX=3702 GN=PERK4 PE=1 SV=1 Length=633 Score = 230 bits (587), Expect = 5e-63, Method: Composition-based stats. Identities = 79/279 (28%), Positives = 124/279 (44%), Gaps = 22/279 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V +G+ VAVK+LKA G R ++ E+DI+ ++H +++ Sbjct 290 LGQGGFGYVHKGVL-----PSGKEVAVKSLKAGSGQGERE-FQAEVDIISRVHHRYLVSL 343 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGL---AQLLLFAQQICEGMAYLH---A 1016 G C G++ LV E+VP +L +L ++ + + L A +G+AYLH Sbjct 344 VGYCIADGQR--MLVYEFVPNKTLEYHLHGKNLPVMEFSTRLRIALGAAKGLAYLHEDCH 401 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ + N+LLD + + DFGLAK + + + R + APE Sbjct 402 PRIIHRDIKSANILLDFNFDAMVADFGLAKLTSDNNTHVSTR--VMGTFGYLAPEYASSG 459 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT-VLRLTELLERGERLP 1135 K SDV+S+GV L EL+T + T L+ A+ M L E + Sbjct 460 KLTEKSDVFSYGVMLLELITGKRPVDNSITMDDTLVDWARPLMARALEDGNFNELADARL 519 Query 1136 RPDKCPCEVYHLMKNC----WETEASFRPTFENLIPILK 1170 + P E+ M C RP ++ L+ Sbjct 520 EGNYNPQEMAR-MVTCAAASIRHSGRKRPKMSQIVRALE 557 Score = 211 bits (538), Expect = 1e-56, Method: Composition-based stats. Identities = 66/378 (17%), Positives = 115/378 (30%), Gaps = 54/378 (14%) Query 552 LPQPGETSNLII--MRGARASPRT-----LNLSQLSFHRVDQKE--ITQLSHLGQGTRTN 602 +P GE S++ R P N S ++ + T + LGQG Sbjct 238 MPTSGEDSSMYSGPSRPVLPPPSPALALGFNKSTFTYQELAAATGGFTDANLLGQGGFGY 297 Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662 V++G L V +K L F ++ Sbjct 298 VHKGVLPSGK-------------------------EVAVKSLKAGSGQGEREFQAEVDII 332 Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASA 721 S+V H +L + G C+ + ++V E+V + L+ L + + + ++ +A A Sbjct 333 SRVHHRYLVSLVGYCIADGQRMLVYEFVPNKTLEYHLHGKNLPVMEFSTRLRIALGAAKG 392 Query 722 LSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV----- 773 L+YL ++H ++ NILL + ++D G+ V Sbjct 393 LAYLHEDCHPRIIHRDIKSANILLD-------FNFDAMVADFGLAKLTSDNNTHVSTRVM 445 Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833 +LAPE G L+ D + +G LLE+ S + + + R Sbjct 446 GTFGYLAPEYASSG--KLTEKSDVFSYGVMLLELITGKRPVDNSITMDDTLVDWARPLMA 503 Query 834 PEPSCPQLATLTSQCL--TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV 891 L L Y P + T R + + Sbjct 504 RALEDGNFNELADARLEGNYNPQEMARMVTCAAASIRHSGRKRPKMSQIVRALEGEVSLD 563 Query 892 FHKRYLKKIRDLGEGHFG 909 +K G G Sbjct 564 ALNEGVKPGHSNVYGSLG 581 >sp|Q80YP0|CDK3_MOUSE Cyclin-dependent kinase 3 OS=Mus musculus OX=10090 GN=Cdk3 PE=1 SV=3 Length=304 Score = 220 bits (560), Expect = 5e-63, Method: Composition-based stats. Identities = 76/292 (26%), Positives = 127/292 (43%), Gaps = 30/292 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y N TG++VA+K ++ D + S +EI +L+ Sbjct 1 MDVFQKVEKIGEGTYGVV----YKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009 L H +IIK EK L +V E++ L+ ++ P + L + + Q+ E Sbjct 57 ELKHPNIIKLLDVVHR--EKKLYMVFEFLTQ-DLKRHMDSSPTSELPLPVVKSYLAQLLE 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 G+++ H+ IHRDL +N+LLD +K+ DFGLA+A Y +++ A Sbjct 114 GVSFCHSHRVIHRDLKPQNLLLDGLGAIKLADFGLARAFGVPLRTY---THEVVTLWYRA 170 Query 1070 PECLKEYK-FYYASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIGIAQG------ 1117 PE L K + A D+WS G E++T DS + +G Sbjct 171 PEILLGSKFYSTAVDIWSIGCIFAEMVTGKALFPGDSEIDQLFRIFRTLGTPSEATWPGV 230 Query 1118 -QMTVLR--LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 QM + + +G P P E L+ + + S R + + + Sbjct 231 SQMPDYQSSFPKWSRKGLEEIVPSLGP-EGKDLLLRLLQYDPSQRISAKTAL 281 Score = 169 bits (427), Expect = 3e-45, Method: Composition-based stats. Identities = 52/263 (20%), Positives = 94/263 (36%), Gaps = 40/263 (15%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--VLDP 646 ++ +G+GT VY+ R +V G V LK LD Sbjct 4 FQKVEKIGEGTYGVVYKARNKVTGQ------------------------LVALKKIRLDL 39 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GH 705 + SL+ ++ H ++ + V R + MV E++ L + Sbjct 40 EAEGVPSTAVREISLLKELKHPNIIKLLDVVHREKKLYMVFEFLTQ-DLKRHMDSSPTSE 98 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 +P+ QL +S+ + ++H ++ +N+LL LG IKL+D G+ Sbjct 99 LPLPVVKSYLAQLLEGVSFCHSHRVIHRDLKPQNLLLDGLGA-------IKLADFGLARA 151 Query 766 ----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + V + + APE L G STA+D W G E+ Sbjct 152 FGVPLRTYTHEVVTLWYRAPEILLGSKF-YSTAVDIWSIGCIFAEMVTGKALFPGDSEID 210 Query 822 EKEHFYQRQHRLPEPSCPQLATL 844 + ++ E + P ++ + Sbjct 211 QLFRIFRTLGTPSEATWPGVSQM 233 >sp|P59895|NEK6_RAT Serine/threonine-protein kinase Nek6 OS=Rattus norvegicus OX=10116 GN=Nek6 PE=1 SV=1 Length=313 Score = 220 bits (561), Expect = 5e-63, Method: Composition-based stats. Identities = 68/330 (21%), Positives = 127/330 (38%), Gaps = 34/330 (10%) Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911 +P+ P + L P + D + + +G G F +V Sbjct 4 QPSHMPHGGSPNHLCHVLGPAHPPDPQRHPNTLSFRC----SLADFQIEKKIGRGQFSEV 59 Query 912 SLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 Y T + VA+K ++ + R +EI +L+ L H +IIKY + Sbjct 60 ----YKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIED 115 Query 970 GEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDL 1024 E L +V+E G L + + I + + Q+C + ++H++ +HRD+ Sbjct 116 NE--LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDI 173 Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084 NV + +VK+GD GL + ++ +PE + E + + SD+ Sbjct 174 KPANVFITATGIVKLGDLGLGRFFS---SETTAAHSLVGTPYYMSPERIHENGYNFKSDI 230 Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP-DKCPCE 1143 WS G LYE+ +M + L + +E+ + P P + + Sbjct 231 WSLGCLLYEMAALQSPFYG-------------DKMNLFSLCQKIEQCDYPPLPGEHYSEK 277 Query 1144 VYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + L+ C + + RP E + + K +H Sbjct 278 LRELVSMCIYPDPNHRPDIEYVHQVAKQMH 307 Score = 169 bits (428), Expect = 3e-45, Method: Composition-based stats. Identities = 52/332 (16%), Positives = 108/332 (33%), Gaps = 41/332 (12%) Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 +P G ++L + G P R + +G+G + VY+ ++ Sbjct 8 MPHGGSPNHLCHVLGPAHPPDPQRHPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLD 67 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 + E R +K L+ Q++H ++ Sbjct 68 RKTVALKKVQIFEMMDAKARQD------CVK---------------EIGLLKQLNHPNII 106 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDV---WLRRERGHVPMAWKMVVAQQLASALSYLENK 728 + E +V E + G L + ++++ +P QL SA+ ++ ++ Sbjct 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 166 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER----VERIPWLAPECL 784 ++H ++ N+ + G+ +KL D G+G S V +++PE + Sbjct 167 RVMHRDIKPANVFITATGI-------VKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERI 219 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS----EKEHFYQRQHRLPEPSCPQ 840 + D W G L E+ + +K E + Sbjct 220 HENGYNF--KSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEK 277 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 L L S C+ +P RP + + ++ Sbjct 278 LRELVSMCIYPDPNHRPDIEYVHQVAKQMHVW 309 >sp|Q9Z1J2|NEK4_MOUSE Serine/threonine-protein kinase Nek4 OS=Mus musculus OX=10090 GN=Nek4 PE=1 SV=1 Length=792 Score = 233 bits (595), Expect = 6e-63, Method: Composition-based stats. Identities = 64/279 (23%), Positives = 117/279 (42%), Gaps = 27/279 (10%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDI 950 + +R +G G +G+V+L + G+ +K L + + R +QE + Sbjct 1 MPQAAYCYMRVVGRGSYGEVTLV----KHRRDGKQYVIKKLNLRNASSRERRAAEQEAQL 56 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQI 1007 L L H +I+ YK E G+ L +VM + G L L + +Q++ + QI Sbjct 57 LSQLKHPNIVTYKESWE-GGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPESQVVEWFVQI 115 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH +H +HRDL +NV L ++K+GD G+A+ + + + ++ Sbjct 116 AMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVL---ENHGDMASTLIGTPYY 172 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 +PE + Y SDVW+ G +YE+ T + + L Sbjct 173 MSPELFSNKPYNYKSDVWALGCCVYEMATLKHAF---------------NAKDMNSLVYR 217 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + G+ P P E+ L++ RP+ +++ Sbjct 218 IIEGKLPPMPKVYSTELAELIRTMLSRRPEERPSVRSIL 256 Score = 172 bits (437), Expect = 5e-43, Method: Composition-based stats. Identities = 58/288 (20%), Positives = 106/288 (37%), Gaps = 38/288 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + +G+G+ V LV R G++ + L + Sbjct 8 YMRVVGRGSYGEV----------------------TLVKHRRDGKQYVIKKLNLRNASSR 45 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPEN-IMVTEYVEHGPLDVWLRRERGHV-PM 708 A + A L+SQ+ H ++ G +V + E G L L+ ++G + P Sbjct 46 ERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPE 105 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + + Q+A AL YL K+++H ++ +N+ L R + IK+ D G+ + Sbjct 106 SQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNI-------IKVGDLGIARVLEN 158 Query 769 R----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + +++PE + D W G + E+ A S Sbjct 159 HGDMASTLIGTPYYMSPELFSNKPYNY--KSDVWALGCCVYEMATLKHAFNAKDMNSLVY 216 Query 825 HFYQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 + + +P+ +LA L L+ P +RPS R+ILR Sbjct 217 RIIEGKLPPMPKVYSTELAELIRTMLSRRPEERPSVRSILRQPYIKHH 264 >sp|P0DH86|SRK_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase SRK OS=Arabidopsis thaliana OX=3702 GN=SRK PE=2 SV=1 Length=853 Score = 234 bits (598), Expect = 6e-63, Method: Composition-based stats. Identities = 72/283 (25%), Positives = 116/283 (41%), Gaps = 26/283 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V G+ +AVK L ++ Q + +K E+ ++ L H ++++ Sbjct 530 LGRGGFGIVYKGRL-----LDGQEIAVKRL-SEMSSQGTNEFKNEVRLIARLQHINLVRL 583 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-----HSIGLAQLLLFAQQICEGMAYLHAQ 1017 CC EK L+ EY+ GSL +L + + I G+ YLH Sbjct 584 LSCCIYADEK--ILIYEYLENGSLDSHLFETTQSSNKLNWQTRFSIINGIARGLLYLHQD 641 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL A NVLLD + KI DFG+A+ R+ + +PE Sbjct 642 SRFKIIHRDLKASNVLLDKNMTPKISDFGMARIFERDETEANTRK-VVGTYGYMSPEYAM 700 Query 1075 EYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 E F SDV+SFGV + E+++ + L+G + E+++ Sbjct 701 EGIFSVKSDVFSFGVLVLEIVSGKRNRGFHNSGQDNNLLGYTWENWKEGKGLEIVDSIIV 760 Query 1134 -------LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 L +P + + C + A RP +++ +L Sbjct 761 DSSSSMSLFQPHEVL-RCIQIGLLCVQERAEDRPKMSSVVLML 802 Score = 218 bits (555), Expect = 2e-57, Method: Composition-based stats. Identities = 49/262 (19%), Positives = 88/262 (34%), Gaps = 46/262 (18%) Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 + + + + LG+G VY+GRL Sbjct 514 FETVVMATENFSDSNILGRGGFGIVYKGRLLDGQ-------------------------E 548 Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 + +K L F L++++ H +L + C+ E I++ EY+E+G LD Sbjct 549 IAVKRLSEMSSQGTNEFKNEVRLIARLQHINLVRLLSCCIYADEKILIYEYLENGSLDSH 608 Query 699 LR---RERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752 L + + + + +A L YL ++H ++ N+LL + + Sbjct 609 LFETTQSSNKLNWQTRFSIINGIARGLLYLHQDSRFKIIHRDLKASNVLLDK-------N 661 Query 753 PFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 K+SD G+ E V +++PE G S D + FG +LE Sbjct 662 MTPKISDFGMARIFERDETEANTRKVVGTYGYMSPEYAMEGI--FSVKSDVFSFGVLVLE 719 Query 807 ICFDGEAPLQSRSPSEKEHFYQ 828 I S + Sbjct 720 IVSGKRNRGFHNSGQDNNLLGY 741 >sp|A7MBB4|M3K13_BOVIN Mitogen-activated protein kinase kinase kinase 13 OS=Bos taurus OX=9913 GN=MAP3K13 PE=2 SV=1 Length=966 Score = 236 bits (602), Expect = 6e-63, Method: Composition-based stats. Identities = 83/301 (28%), Positives = 122/301 (41%), Gaps = 35/301 (12%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + + + + D + +++ LG G G V L + E VA+K Sbjct 142 WNIIGKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRA------EEVAIK 195 Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 ++ I LR L H +II +KG C ++MEY G L + L Sbjct 196 KVREQNETD--------IKHLRKLKHPNIIAFKGVCTQA--PCYCIIMEYCAHGQLYEVL 245 Query 991 P-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 I L+ ++ I GM YLH IHRDL + NVL+ + VKI DFG +K + Sbjct 246 RAGRKITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELS 305 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 + + V W APE ++ D+WSFGV L+ELLT P K + Sbjct 306 D----KSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTG-----EIPYKDV 356 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + I G + LP P CP LMK W+++ RP+F + L Sbjct 357 DSSAIIWGVGSN---------SLHLPVPSTCPDGFKILMKQTWQSKTRNRPSFRQTLMHL 407 Query 1170 K 1170 Sbjct 408 D 408 Score = 211 bits (537), Expect = 9e-55, Method: Composition-based stats. Identities = 64/305 (21%), Positives = 108/305 (35%), Gaps = 50/305 (16%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 +A L Q V +EI++L LG G + V+ G+ R E Sbjct 146 GKAYSTDYKLQQQDTWEVPFEEISELQWLGSGAQGAVFLGKFRAE--------------- 190 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 V +K + + + ++ H ++ GVC + P ++ Sbjct 191 -----------EVAIKKVREQNE-------TDIKHLRKLKHPNIIAFKGVCTQAPCYCII 232 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 EY HG L LR R + + + +AS ++YL ++H ++ N+L+ Sbjct 233 MEYCAHGQLYEVLRAGR-KITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTD 291 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 +K+SD G + ++ + W+APE + +S +D W FG Sbjct 292 A-------VKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRN--EPVSEKVDIWSFGVV 342 Query 804 LLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 L E+ GE P + S +P L Q + RPSFR Sbjct 343 LWELL-TGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKTRNRPSFR 401 Query 861 TILRD 865 L Sbjct 402 QTLMH 406 >sp|Q99N57|RAF1_MOUSE RAF proto-oncogene serine/threonine-protein kinase OS=Mus musculus OX=10090 GN=Raf1 PE=1 SV=2 Length=648 Score = 230 bits (587), Expect = 6e-63, Method: Composition-based stats. Identities = 80/333 (24%), Positives = 135/333 (41%), Gaps = 35/333 (11%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 + T P+ R + + +S + +G G F Sbjct 305 WSQPKTPVPAQRERAPGSGT----QEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF 360 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 G V + VAVK LK D P+ ++ E+ +LR H +I+ + G Sbjct 361 GTVYKGKWHG-------DVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILLFMGYM- 412 Query 968 DQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 + +L +V ++ SL +L + QL+ A+Q +GM YLHA++ IHRD+ Sbjct 413 --TKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMK 470 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYAS 1082 + N+ L VKIGDFGLA +V E V W APE ++ + F + S Sbjct 471 SNNIFLHEGLTVKIGDFGLATVKSRWSGSQQV-EQPTGSVLWMAPEVIRMQDDNPFSFQS 529 Query 1083 DVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 DV+S+G+ LYEL+ + + ++G + RL + C Sbjct 530 DVYSYGIVLYELMAGELPYAHINNRDQIIFMVGRGYASPDLSRLYK------------NC 577 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 P + L+ +C + RP F ++ ++ + Sbjct 578 PKAMKRLVADCVKKVKEERPLFPQILSSIELLQ 610 Score = 222 bits (565), Expect = 5e-60, Method: Composition-based stats. Identities = 70/367 (19%), Positives = 127/367 (35%), Gaps = 62/367 (17%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 R + N I RG R S + ++ E+ + +G G+ VY+G+ Sbjct 316 RERAPGSGTQEKNKIRPRGQRDSSY--------YWEIEASEVMLSTRIGSGSFGTVYKGK 367 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQ 664 + V +K+L DP+ + AF +++ + Sbjct 368 WHGD---------------------------VAVKILKVVDPTPEQLQ-AFRNEVAVLRK 399 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 H ++ G + +VT++ E L L + M + +A+Q A + Y Sbjct 400 TRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778 L KN++H ++ NI L +K+ D G+ G+ E+ + W Sbjct 459 LHAKNIIHRDMKSNNIFLHEGL-------TVKIGDFGLATVKSRWSGSQQVEQPTGSVLW 511 Query 779 LAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH------ 831 +APE + N S D + +G L E+ GE P + ++ F + Sbjct 512 MAPEVIRMQDDNPFSFQSDVYSYGIVLYELMA-GELPYAHINNRDQIIFMVGRGYASPDL 570 Query 832 -RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 RL + + L + C+ +RP F IL + LQ + + S Sbjct 571 SRLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAH 630 Query 891 VFHKRYL 897 Sbjct 631 TEDINAC 637 >sp|O65238|Y5537_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At5g35370 OS=Arabidopsis thaliana OX=3702 GN=At5g35370 PE=2 SV=2 Length=872 Score = 234 bits (598), Expect = 6e-63, Method: Composition-based stats. Identities = 76/379 (20%), Positives = 125/379 (33%), Gaps = 59/379 (16%) Query 471 YLIHWSTSHPYRLILTVAQRSQAPD--GMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRE 528 YL+ S L L V + D G L +RK + G SFP + Sbjct 395 YLVKDS---FGSLSL-VKNSPENHDLIGYVKLSIRKTNAQPPGNN---NRGGSSFPVIAL 447 Query 529 LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL-------SQLSF 581 + G L RRC + + + R L + F Sbjct 448 VLLPCSGFFLLIALGLLWWRRCAVMRYSSIREKQVTRPGSFESGDLGSFHIPGLPQKFEF 507 Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 ++Q +G G +VY+G L E + + Sbjct 508 EELEQATENFKMQIGSGGFGSVYKGTL-------------------------PDETLIAV 542 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 K + F +++ + HT+L + G C RG + ++V EY+ HG L+ L Sbjct 543 KKITNHGLHGRQEFCTEIAIIGNIRHTNLVKLRGFCARGRQLLLVYEYMNHGSLEKTLFS 602 Query 702 ERGH-VPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 G + + +A A L+YL + + ++H +V NILL K+ Sbjct 603 GNGPVLEWQERFDIALGTARGLAYLHSGCDQKIIHCDVKPENILL-------HDHFQPKI 655 Query 758 SDPGVGLGALSRE-----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 SD G+ E +LAPE + A +S D + +G LLE+ + Sbjct 656 SDFGLSKLLNQEESSLFTTMRGTRGYLAPEWITNAA--ISEKADVYSYGMVLLELVSGRK 713 Query 813 APLQSRSPSEKEHFYQRQH 831 + + H Sbjct 714 NCSFRSRSNSVTEDNNQNH 732 Score = 221 bits (563), Expect = 2e-58, Method: Composition-based stats. Identities = 69/319 (22%), Positives = 121/319 (38%), Gaps = 36/319 (11%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + + + +G G FG V ++AVK + + G Sbjct 496 FHIPGLPQKFEFEELEQATENFKMQIGSGGFGSVYKGTL-----PDETLIAVKKI-TNHG 549 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--- 994 R + EI I+ + H +++K +G C + L LV EY+ GSL L + Sbjct 550 LHGRQEFCTEIAIIGNIRHTNLVKLRGFCARG--RQLLLVYEYMNHGSLEKTLFSGNGPV 607 Query 995 IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 + + A G+AYLH+ Q IH D+ N+LL + KI DFGL+K + Sbjct 608 LEWQERFDIALGTARGLAYLHSGCDQKIIHCDVKPENILLHDHFQPKISDFGLSKLL--N 665 Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC------------- 1098 E + + APE + +DV+S+G+ L EL++ Sbjct 666 QEESSLFTTMRGTRGYLAPEWITNAAISEKADVYSYGMVLLELVSGRKNCSFRSRSNSVT 725 Query 1099 -DSSQSPPTKFLELIGIAQGQMTVL------RLTELLERGERLPRPDKCPCEVYHLMKNC 1151 D++Q+ + G+ + L R EL + + ++ + C Sbjct 726 EDNNQNHSSTTTTSTGLVYFPLYALDMHEQGRYMELADPRLEGRVTSQEAEKLVRIALCC 785 Query 1152 WETEASFRPTFENLIPILK 1170 E + RPT ++ + + Sbjct 786 VHEEPALRPTMAAVVGMFE 804 >sp|Q03141|MARK3_MOUSE MAP/microtubule affinity-regulating kinase 3 OS=Mus musculus OX=10090 GN=Mark3 PE=1 SV=2 Length=753 Score = 233 bits (593), Expect = 6e-63, Method: Composition-based stats. Identities = 76/280 (27%), Positives = 118/280 (42%), Gaps = 29/280 (10%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEID 949 H + ++ +G+G+F KV L + TG VA+K + K P +E+ Sbjct 50 QPHIGNYRLLKTIGKGNFAKVKL----ARHILTGREVAIKIIDKTQLNPTSLQKLFREVR 105 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQIC 1008 I++ L H +I+K E EK+L L+MEY G + DYL H + + +QI Sbjct 106 IMKILNHPNIVKLFEVIE--TEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIV 163 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 + Y H + +HRDL A N+LLD D +KI DFG + G + + + Sbjct 164 SAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGSKL----DTFCGSPPYA 219 Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + K+ DVWS GV LY L++ + L E Sbjct 220 APELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD---------------GQNLKELRER 264 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + RG + P + +L+K R T E ++ Sbjct 265 VLRG-KYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMK 303 Score = 190 bits (483), Expect = 8e-49, Method: Composition-based stats. Identities = 57/319 (18%), Positives = 106/319 (33%), Gaps = 41/319 (13%) Query 556 GETSNLIIMRGARASPRTLN-LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 G+ + R R+ R N ++ + + L +G+G V R + G Sbjct 22 GDGRQEVTSRTGRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGR- 80 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAF 672 V +K++D + + + +M ++H ++ Sbjct 81 -----------------------EVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 117 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVH 732 + V ++ EY G + +L G + +Q+ SA+ Y K +VH Sbjct 118 LFEVIETEKTLYLIMEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYCHQKRIVH 176 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGAN 789 ++ N+LL IK++D G + P+ APE G Sbjct 177 RDLKAENLLLD-------ADMNIKIADFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKY 229 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQC 848 +D W G L + G P ++ E R +R+P L + Sbjct 230 D-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRF 287 Query 849 LTYEPTQRPSFRTILRDLT 867 L P +R + I++D Sbjct 288 LVLNPVKRGTLEQIMKDRW 306 >sp|Q9LJD8|M3KE1_ARATH MAP3K epsilon protein kinase 1 OS=Arabidopsis thaliana OX=3702 GN=M3KE1 PE=1 SV=1 Length=1368 Score = 239 bits (609), Expect = 6e-63, Method: Composition-based stats. Identities = 75/294 (26%), Positives = 132/294 (45%), Gaps = 28/294 (10%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + S + ++G+G +G+V Y + G+ VA+K + + Sbjct 1 MARQMTSSQFHKSKTLDNKYMLGDEIGKGAYGRV----YKGLDLENGDFVAIKQVSLENI 56 Query 938 PQHR-SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996 Q + QEID+L+ L H++I+KY G + + L +++EYV GSL + + + G Sbjct 57 VQEDLNTIMQEIDLLKNLNHKNIVKYLGS--SKTKTHLHIILEYVENGSLANIIKPNKFG 114 Query 997 ---LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + + ++ Q+ EG+ YLH Q IHRD+ N+L + LVK+ DFG+A + E Sbjct 115 PFPESLVAVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGLVKLADFGVATKLNEAD- 173 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 +W APE ++ ASD+WS G T+ ELLT Sbjct 174 --VNTHSVVGTPYWMAPEVIEMSGVCAASDIWSVGCTVIELLTCVPPYYD---------- 221 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 Q + R+ + + P PD ++ ++ C++ ++ RP + L+ Sbjct 222 -LQPMPALFRIVQ----DDNPPIPDSLSPDITDFLRQCFKKDSRQRPDAKTLLS 270 Score = 208 bits (530), Expect = 2e-53, Method: Composition-based stats. Identities = 61/305 (20%), Positives = 108/305 (35%), Gaps = 43/305 (14%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 R + SQ + + +G+G VY+G G Sbjct 3 RQMTSSQFHKSKTLDNKYMLGDEIGKGAYGRVYKGLDLENGDF----------------- 45 Query 632 DRGQELRVVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 V +K + + + + L+ ++H ++ G ++ EY Sbjct 46 -------VAIKQVSLENIVQEDLNTIMQEIDLLKNLNHKNIVKYLGSSKTKTHLHIILEY 98 Query 690 VEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 VE+G L ++ + G P + V Q+ L YL + ++H ++ G NIL + GL Sbjct 99 VENGSLANIIKPNKFGPFPESLVAVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGL- 157 Query 749 EGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 +KL+D GV ++ V W+APE + + + A D W G T+ Sbjct 158 ------VKLADFGVATKLNEADVNTHSVVGTPYWMAPEVIEM--SGVCAASDIWSVGCTV 209 Query 805 LEICFDGEAPLQSRSPSEKEH--FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 +E+ P P +P+ P + QC + QRP +T+ Sbjct 210 IELLTC-VPPYYDLQPMPALFRIVQDDNPPIPDSLSPDITDFLRQCFKKDSRQRPDAKTL 268 Query 863 LRDLT 867 L Sbjct 269 LSHPW 273 >sp|Q9LDI3|CIPKO_ARATH CBL-interacting serine/threonine-protein kinase 24 OS=Arabidopsis thaliana OX=3702 GN=CIPK24 PE=1 SV=1 Length=446 Score = 224 bits (572), Expect = 7e-63, Method: Composition-based stats. Identities = 66/262 (25%), Positives = 113/262 (43%), Gaps = 29/262 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959 +GEG F KV N TG+ VA+K + ++R K+EI I++ + H +I Sbjct 16 TIGEGTFAKVKF----ARNTDTGDNVAIKIMAKSTILKNRMVDQIKREISIMKIVRHPNI 71 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ + + +V+E+V G L D + + + ++ + QQ+ + +A+ H + Sbjct 72 VRLYEVLASPSK--IYIVLEFVTGGELFDRIVHKGRLEESESRKYFQQLVDAVAHCHCKG 129 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N+LLD + +K+ DFGL+ EG E R + APE L + Sbjct 130 VYHRDLKPENLLLDTNGNLKVSDFGLSALPQEGVELLRTT---CGTPNYVAPEVLSGQGY 186 Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 A+D+WS GV L+ +L P +L G+ ++ + P Sbjct 187 DGSAADIWSCGVILFVILAG-----YLPFSETDLPGL-YRKINAAEFS----------CP 230 Query 1138 DKCPCEVYHLMKNCWETEASFR 1159 EV L+ + R Sbjct 231 PWFSAEVKFLIHRILDPNPKTR 252 Score = 175 bits (443), Expect = 8e-46, Method: Composition-based stats. Identities = 56/293 (19%), Positives = 100/293 (34%), Gaps = 42/293 (14%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 RV + E+ +G+GT V R+ V +K Sbjct 7 RVGKYEV--GRTIGEGTFAKV------------------------KFARNTDTGDNVAIK 40 Query 643 VLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 ++ S + + S+M V H ++ ++ V + +V E+V G L + Sbjct 41 IMAKSTILKNRMVDQIKREISIMKIVRHPNIVRLYEVLASPSKIYIVLEFVTGGELFDRI 100 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 +G + + QQL A+++ K + H ++ N+LL T+ +K+SD Sbjct 101 -VHKGRLEESESRKYFQQLVDAVAHCHCKGVYHRDLKPENLLLD-------TNGNLKVSD 152 Query 760 PGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ G ++APE L G +A D W G L I Sbjct 153 FGLSALPQEGVELLRTTCGTPNYVAPEVLSGQGYD-GSAADIWSCGVILFVILAGYLPFS 211 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 ++ P + P ++ L + L P R + I +D Sbjct 212 ETDLPGLYRKINAAEFSCPPWFSAEVKFLIHRILDPNPKTRIQIQGIKKDPWF 264 >sp|A2BD05|NEK6_PIG Serine/threonine-protein kinase Nek6 OS=Sus scrofa OX=9823 GN=NEK6 PE=3 SV=1 Length=313 Score = 220 bits (560), Expect = 7e-63, Method: Composition-based stats. Identities = 61/285 (21%), Positives = 117/285 (41%), Gaps = 30/285 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTL 954 + + +G G F +V Y T + VA+K ++ + R +EI +L+ L Sbjct 45 FQIEKKIGRGQFSEV----YKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQL 100 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICE 1009 H +IIKY + E L +V+E G L + + I + + Q+C Sbjct 101 NHPNIIKYLDSFIEDNE--LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCS 158 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + ++H++ +HRD+ NV + +VK+GD GL + ++ + Sbjct 159 AVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFS---SETTAAHSLVGTPYYMS 215 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE + E + + SD+WS G LYE+ +M + L + +E Sbjct 216 PERIHENGYNFKSDIWSLGCLLYEMAALQSPFYG-------------DKMNLFSLCQKIE 262 Query 1130 RGERLPRP-DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + + P P + ++ L+ C + + RP + + + +H Sbjct 263 QCDYPPLPGEHYSEKLRELVSMCIYPDPNQRPDIGYVHQVARQMH 307 Score = 173 bits (438), Expect = 1e-46, Method: Composition-based stats. Identities = 54/332 (16%), Positives = 108/332 (33%), Gaps = 41/332 (12%) Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 +P G +NL G P R + +G+G + VY+ ++ Sbjct 8 MPHGGSPNNLCHTPGPAHPPDPQRHPNALSFRCSLADFQIEKKIGRGQFSEVYKATCLLD 67 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 + E R +K L+ Q++H ++ Sbjct 68 RKTVALKKVQIFEMMDAKARQD------CVK---------------EIGLLKQLNHPNII 106 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDV---WLRRERGHVPMAWKMVVAQQLASALSYLENK 728 + E +V E + G L + ++++ +P QL SA+ ++ ++ Sbjct 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 166 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER----VERIPWLAPECL 784 ++H ++ N+ + G+ +KL D G+G S V +++PE + Sbjct 167 RVMHRDIKPANVFITATGI-------VKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERI 219 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS----EKEHFYQRQHRLPEPSCPQ 840 + D W G L E+ + +K E + Sbjct 220 HENGYNF--KSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEK 277 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 L L S C+ +P QRP + + ++ Sbjct 278 LRELVSMCIYPDPNQRPDIGYVHQVARQMHVW 309 >sp|Q802A6|STK4_SQUAC Serine/threonine-protein kinase 3/4 OS=Squalus acanthias OX=7797 GN=STK4 PE=2 SV=1 Length=491 Score = 226 bits (575), Expect = 7e-63, Method: Composition-based stats. Identities = 67/304 (22%), Positives = 116/304 (38%), Gaps = 27/304 (9%) Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE 925 + +Q T + + LGEG +G V + + +G+ Sbjct 1 MEEVQRRQHPHPRRSLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSV----FKAIHKESGQ 56 Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 +VA+K + + Q +EI I++ H++KY G + L +VMEY GS Sbjct 57 VVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVKYYGSYFKNTD--LWIVMEYCGAGS 111 Query 986 LRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFG 1043 + D + ++ ++ Q +G+ YLH IHRD+ A N+LL+N+ K+ DFG Sbjct 112 VSDLIRIRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNNEGHAKLADFG 171 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 +A + + R FW APE ++E + +D+WS G++ E+ Sbjct 172 VAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGISAIEMAEGKPPYAD 228 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163 + I R +P+ E +K C R Sbjct 229 -IHPMRAIFMIPTNPPPTFR------------KPELWTDEFTDFVKQCLVKNPEQRAAAT 275 Query 1164 NLIP 1167 L+ Sbjct 276 QLLQ 279 Score = 203 bits (516), Expect = 6e-55, Method: Composition-based stats. Identities = 61/315 (19%), Positives = 102/315 (32%), Gaps = 46/315 (15%) Query 563 IMRGARASPRTL--NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620 + R PR LS+ S + ++ L LG+G+ +V++ + G Sbjct 4 VQRRQHPHPRRSLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQ------- 56 Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680 V +K + + S+M Q H+ +G + Sbjct 57 -----------------VVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKN 97 Query 681 PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNI 740 + +V EY G + +R + + Q L YL +H ++ NI Sbjct 98 TDLWIVMEYCGAGSVSDLIRIRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNI 157 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMD 796 LL G KL+D GV R + W+APE + + D Sbjct 158 LLNNEG-------HAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQE--IGYNCVAD 208 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYE 852 W G + +E+ +G+ P P R PE + QCL Sbjct 209 IWSLGISAIEMA-EGKPPYADIHPMRAIFMIPTNPPPTFRKPELWTDEFTDFVKQCLVKN 267 Query 853 PTQRPSFRTILRDLT 867 P QR + +L+ Sbjct 268 PEQRAAATQLLQHPF 282 >sp|Q9SI06|Y5573_ARATH Putative leucine-rich repeat receptor-like serine/threonine-protein kinase At2g04300 OS=Arabidopsis thaliana OX=3702 GN=At2g04300 PE=3 SV=2 Length=892 Score = 235 bits (599), Expect = 8e-63, Method: Composition-based stats. Identities = 70/322 (22%), Positives = 131/322 (41%), Gaps = 21/322 (7%) Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918 FR + + + T+ + + K + LG+G FG V Sbjct 544 FRKRKTPRNEVSRTSRSLDPTITTKNRRFTYSEVVKMTNNFEKILGKGGFGMVYHGT--- 600 Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978 E VAVK L ++ +K E+++L ++H++++ G C++ ++L L+ Sbjct 601 --VNDAEQVAVKMLSPSSSQGYKE-FKAEVELLLRVHHKNLVGLVGYCDEG--ENLSLIY 655 Query 979 EYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLL 1031 EY+ G L++++ + + L + +G+ YLH +HRD+ N+LL Sbjct 656 EYMAKGDLKEHMLGNQGVSILDWKTRLKIVAESAQGLEYLHNGCKPPMVHRDVKTTNILL 715 Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091 D K+ DFGL+++ P E RV + PE + SDV+SFG+ L Sbjct 716 DEHFQAKLADFGLSRSFPLEGET-RVDTVVAGTPGYLDPEYYRTNWLNEKSDVYSFGIVL 774 Query 1092 YELLT--HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149 E++T H + E +G+ +T + +++ L Sbjct 775 LEIITNQHVINQSREKPHIAEWVGV---MLTKGDIKSIIDPKFSGDYDAGSVWRAVELAM 831 Query 1150 NCWETEASFRPTFENLIPILKT 1171 +C ++ RPT ++ L Sbjct 832 SCVNPSSTGRPTMSQVVIELNE 853 Score = 211 bits (536), Expect = 6e-55, Method: Composition-based stats. Identities = 71/347 (20%), Positives = 115/347 (33%), Gaps = 64/347 (18%) Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRT 601 R+ P+ + + + T + ++ V + LG+G Sbjct 539 ALFLVFRKRKTPR----NEVSRTSRSLDPTITTKNRRFTYSEVVKMTNNFEKILGKGGFG 594 Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASL 661 VY G + +V +K+L PS F L Sbjct 595 MVYHGTVNDAE-------------------------QVAVKMLSPSSSQGYKEFKAEVEL 629 Query 662 MSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLA 719 + +V H +L + G C G ++ EY+ G L + +G + W ++ + + A Sbjct 630 LLRVHHKNLVGLVGYCDEGENLSLIYEYMAKGDLKEHMLGNQGVSILDWKTRLKIVAESA 689 Query 720 SALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALSREERV-- 773 L YL N +VH +V NILL KL+D G+ L E RV Sbjct 690 QGLEYLHNGCKPPMVHRDVKTTNILLDE-------HFQAKLADFGLSRSFPLEGETRVDT 742 Query 774 ---ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR---SPSEKEHFY 827 +L PE N L+ D + FG LLEI + QSR +E Sbjct 743 VVAGTPGYLDPEYYRT--NWLNEKSDVYSFGIVLLEIITNQHVINQSREKPHIAEWVGVM 800 Query 828 QRQHRLPEPSCPQLA------------TLTSQCLTYEPTQRPSFRTI 862 + + P+ + L C+ T RP+ + Sbjct 801 LTKGDIKSIIDPKFSGDYDAGSVWRAVELAMSCVNPSSTGRPTMSQV 847 >sp|C0LGR6|Y4291_ARATH Probable LRR receptor-like serine/threonine-protein kinase At4g29180 OS=Arabidopsis thaliana OX=3702 GN=At4g29180 PE=1 SV=2 Length=913 Score = 235 bits (599), Expect = 8e-63, Method: Composition-based stats. Identities = 70/328 (21%), Positives = 134/328 (41%), Gaps = 27/328 (8%) Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922 +R +++ + + + +G+G FG V L + Sbjct 533 MRRESKIMYSGAYSGPLLPSGKRRFTYSEVSSITNNFNKVIGKGGFGIVYLGSLE----- 587 Query 923 TGEMVAVKALK------------ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQG 970 G +AVK + + Q ++ E ++L T++H ++ + G C+D Sbjct 588 DGTEIAVKMINDSSFGKSKGSSSSSSSSQVSKEFQVEAELLLTVHHRNLASFVGYCDDG- 646 Query 971 EKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA---QHYIHRDL 1024 +S+ L+ EY+ G+L+DYL + + + L A +G+ YLH +HRD+ Sbjct 647 -RSMALIYEYMANGNLQDYLSSENAEDLSWEKRLHIAIDSAQGLEYLHHGCRPPIVHRDV 705 Query 1025 AARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084 N+LL+++ KI DFGL+K PE + V +P + PE +K SDV Sbjct 706 KTANILLNDNLEAKIADFGLSKVFPEDDLSHVVTAVMGTP-GYVDPEYYNTFKLNEKSDV 764 Query 1085 WSFGVTLYELLTHCDSSQSPPTKF-LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCE 1143 +SFG+ L EL+T S + ++ + + + + +++ + Sbjct 765 YSFGIVLLELITGKRSIMKTDDGEKMNVVHYVEPFLKMGDIDGVVDPRLHGDFSSNSAWK 824 Query 1144 VYHLMKNCWETEASFRPTFENLIPILKT 1171 + +C + RP ++ LK Sbjct 825 FVEVAMSCVRDRGTNRPNTNQIVSDLKQ 852 Score = 190 bits (483), Expect = 3e-48, Method: Composition-based stats. Identities = 49/275 (18%), Positives = 89/275 (32%), Gaps = 31/275 (11%) Query 579 LSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 ++ V +G+G VY G L + + Sbjct 557 FTYSEVSSITNNFNKVIGKGGFGIVYLGSLEDGTEIAVKMINDSSFGKSKGSSSSSSSSQ 616 Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 V + F A L+ V H +LA G C G ++ EY+ +G L + Sbjct 617 V------------SKEFQVEAELLLTVHHRNLASFVGYCDDGRSMALIYEYMANGNLQDY 664 Query 699 LRRERGH-VPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPF 754 L E + ++ +A A L YL + +VH +V NILL + Sbjct 665 LSSENAEDLSWEKRLHIAIDSAQGLEYLHHGCRPPIVHRDVKTANILLN-------DNLE 717 Query 755 IKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 K++D G+ + + ++ PE L+ D + FG LLE+ Sbjct 718 AKIADFGLSKVFPEDDLSHVVTAVMGTPGYVDPEYY--NTFKLNEKSDVYSFGIVLLELI 775 Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT 843 + +++ + + + L + Sbjct 776 TGKRSIMKTDDGEKMNVVHYVEPFLKMGDIDGVVD 810 >sp|Q08E52|PAK1_BOVIN Serine/threonine-protein kinase PAK 1 OS=Bos taurus OX=9913 GN=PAK1 PE=1 SV=1 Length=544 Score = 227 bits (579), Expect = 8e-63, Method: Composition-based stats. Identities = 68/372 (18%), Positives = 127/372 (34%), Gaps = 24/372 (6%) Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 G P E + + + + ++ + R+ + + Sbjct 183 GTPPPVIAPRPEHTKSVYTRSVIEPLPITPTRDVATSPISPTENNTTPPDALTRNTEKQK 242 Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + + K+ + +G+G G V Y + TG+ VA+K Sbjct 243 KKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV----YTAMDVATGQEVAIK 298 Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 + P+ + EI ++R + +I+ Y E L +VMEY+ GSL D + Sbjct 299 QMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVV 355 Query 991 PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 + Q+ ++ + + +LH+ IHRD+ + N+LL D VK+ DFG + Sbjct 356 TETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITP 415 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 R +W APE + + D+WS G+ E++ PP Sbjct 416 ---EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI-----EGEPPYLNEN 467 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP-IL 1169 + T L P+K + C E + R + + L+ Sbjct 468 PLRALYLIATNGT--------PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF 519 Query 1170 KTVHEKYQGQAP 1181 + + P Sbjct 520 LKIAKPLSSLTP 531 Score = 181 bits (458), Expect = 6e-47, Method: Composition-based stats. Identities = 54/291 (19%), Positives = 97/291 (33%), Gaps = 44/291 (15%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +K+ T+ +GQG VY D V +K + Sbjct 265 PKKKYTRFEKIGQGASGTVY------------------------TAMDVATGQEVAIKQM 300 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + +M + + ++ + G E +V EY+ G L + Sbjct 301 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 358 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + V ++ AL +L + ++H ++ NILL G +KL+D G Sbjct 359 CMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 411 Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 R V W+APE + A +D W G +E+ +GE P + +P Sbjct 412 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMI-EGEPPYLNENP 468 Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + PE ++CL + +R S + +L+ Sbjct 469 LRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF 519 >sp|Q8GZ99|HPCA1_ARATH Leucine-rich repeat receptor protein kinase HPCA1 OS=Arabidopsis thaliana OX=3702 GN=HPCA1 PE=1 SV=1 Length=953 Score = 236 bits (601), Expect = 8e-63, Method: Composition-based stats. Identities = 71/259 (27%), Positives = 120/259 (46%), Gaps = 11/259 (4%) Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982 G+++A+K Q +K EI++L ++H+++++ G C D+ E+ LV EY+ Sbjct 652 NGQLIAIKR-AQQGSLQGGLEFKTEIELLSRVHHKNVVRLLGFCFDRNEQ--MLVYEYIS 708 Query 983 LGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRL 1036 GSL+D L S + + L A +G+AYLH IHRD+ + N+LLD + Sbjct 709 NGSLKDSLSGKSGIRLDWTRRLKIALGSGKGLAYLHELADPPIIHRDIKSNNILLDENLT 768 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 K+ DFGL+K V + + + V + + PE + SDV+ FGV L ELLT Sbjct 769 AKVADFGLSKLVGDPEKTH-VTTQVKGTMGYLDPEYYMTNQLTEKSDVYGFGVVLLELLT 827 Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD-KCPCEVYHLMKNCWETE 1155 + E+ ++ L ELL+ + K + L C E E Sbjct 828 GRSPIERGKYVVREVKTKMNKSRSLYDLQELLDTTIIASSGNLKGFEKYVDLALRCVEEE 887 Query 1156 ASFRPTFENLIPILKTVHE 1174 RP+ ++ ++ + + Sbjct 888 GVNRPSMGEVVKEIENIMQ 906 Score = 195 bits (495), Expect = 1e-49, Method: Composition-based stats. Identities = 57/293 (19%), Positives = 101/293 (34%), Gaps = 28/293 (10%) Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 + + RA T + + + I +G T +E + + Sbjct 581 ALRQKKRAERATGQNNPFAKWDTSKSSIDAPQLMGAKAFT--FEELKKCTDNFSEANDVG 638 Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 V + +K L F L+S+V H ++ + G C Sbjct 639 GGGYGKVYRGILPNGQLIAIKRAQQGSLQGGLEFKTEIELLSRVHHKNVVRLLGFCFDRN 698 Query 682 ENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCG 737 E ++V EY+ +G L L + G + ++ +A L+YL ++H ++ Sbjct 699 EQMLVYEYISNGSLKDSLSGKSGIRLDWTRRLKIALGSGKGLAYLHELADPPIIHRDIKS 758 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSL 791 NILL + K++D G+ E+ + +L PE N L Sbjct 759 NNILLDE-------NLTAKVADFGLSKLVGDPEKTHVTTQVKGTMGYLDPEYYMT--NQL 809 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATL 844 + D +GFG LLE+ RSP E+ + R+ + L L Sbjct 810 TEKSDVYGFGVVLLELLT-------GRSPIERGKYVVREVKTKMNKSRSLYDL 855 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 Length=753 Score = 232 bits (592), Expect = 8e-63, Method: Composition-based stats. Identities = 76/280 (27%), Positives = 118/280 (42%), Gaps = 29/280 (10%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEID 949 H + ++ +G+G+F KV L + TG VA+K + K P +E+ Sbjct 50 QPHIGNYRLLKTIGKGNFAKVKL----ARHILTGREVAIKIIDKTQLNPTSLQKLFREVR 105 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQIC 1008 I++ L H +I+K E EK+L L+MEY G + DYL H + + +QI Sbjct 106 IMKILNHPNIVKLFEVIE--TEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIV 163 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 + Y H + +HRDL A N+LLD D +KI DFG + G + + + Sbjct 164 SAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKL----DTFCGSPPYA 219 Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + K+ DVWS GV LY L++ + L E Sbjct 220 APELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD---------------GQNLKELRER 264 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + RG + P + +L+K R T E ++ Sbjct 265 VLRG-KYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMK 303 Score = 190 bits (482), Expect = 1e-48, Method: Composition-based stats. Identities = 57/319 (18%), Positives = 107/319 (34%), Gaps = 41/319 (13%) Query 556 GETSNLIIMRGARASPRTLN-LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 G+ + R +R+ R N ++ + + L +G+G V R + G Sbjct 22 GDGRQEVTSRTSRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGR- 80 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAF 672 V +K++D + + + +M ++H ++ Sbjct 81 -----------------------EVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 117 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVH 732 + V ++ EY G + +L G + +Q+ SA+ Y K +VH Sbjct 118 LFEVIETEKTLYLIMEYASGGEVFDYLVAH-GRMKEKEARSKFRQIVSAVQYCHQKRIVH 176 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGAN 789 ++ N+LL IK++D G + P+ APE G Sbjct 177 RDLKAENLLLD-------ADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKY 229 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQC 848 +D W G L + G P ++ E R +R+P L + Sbjct 230 D-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRF 287 Query 849 LTYEPTQRPSFRTILRDLT 867 L P +R + I++D Sbjct 288 LVLNPIKRGTLEQIMKDRW 306 >sp|A8X775|DLK1_CAEBR Mitogen-activated protein kinase kinase kinase dlk-1 OS=Caenorhabditis briggsae OX=6238 GN=dlk-1 PE=3 SV=1 Length=857 Score = 234 bits (597), Expect = 8e-63, Method: Composition-based stats. Identities = 76/277 (27%), Positives = 119/277 (43%), Gaps = 34/277 (12%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + + LG G G V Y+ VAVK + + EI Sbjct 55 WEIPFDAISNLEWLGSGSQGAVFHGQYE------NRTVAVKKVNQLK--------ETEIK 100 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQIC 1008 LR L H++II++ G C +VMEY P G L L + ++ Q+ + ++I Sbjct 101 HLRHLRHKNIIEFLGVCSKS--PCYCIVMEYCPKGQLCTVLRQKNLITRQMFSDWVKEIA 158 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +GM YLH IHRDL + N+L+ + +KI DFG + + V W Sbjct 159 DGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTSHLQKKND---STMMSFCGTVSWM 215 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 APE +K+ DV+SFGV L+E+LT ++P ++ I +L Sbjct 216 APEMIKKEPCNEKVDVYSFGVVLWEMLTR----ETPYANIAQMAIIFGVGTNILN----- 266 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 LP P++ P + L+K C + RP+F ++ Sbjct 267 -----LPMPEEAPRGLVLLIKQCLSQKGRNRPSFSHI 298 Score = 199 bits (506), Expect = 3e-51, Method: Composition-based stats. Identities = 58/348 (17%), Positives = 110/348 (32%), Gaps = 51/348 (15%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 + + ++ + I+ L LG G++ V+ G+ Sbjct 40 GGKPTQEIEKTEDEGWEIPFDAISNLEWLGSGSQGAVFHGQ------------------- 80 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 + V +K ++ + + H ++ GVC + P +V Sbjct 81 -------YENRTVAVKKVNQLKE-------TEIKHLRHLRHKNIIEFLGVCSKSPCYCIV 126 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 EY G L LR ++ + +++A + YL ++H ++ NIL++ Sbjct 127 MEYCPKGQLCTVLR-QKNLITRQMFSDWVKEIADGMHYLHQNKVIHRDLKSPNILIS--- 182 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV----ERIPWLAPECLPGGANSLSTAMDKWGFGA 802 IK+ D G + + + W+APE + + +D + FG Sbjct 183 ----AEDSIKICDFGTSHLQKKNDSTMMSFCGTVSWMAPEMIK--KEPCNEKVDVYSFGV 236 Query 803 TLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSF 859 L E+ E P + + +PE + L L QCL+ + RPSF Sbjct 237 VLWEMLTR-ETPYANIAQMAIIFGVGTNILNLPMPEEAPRGLVLLIKQCLSQKGRNRPSF 295 Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 I + +P + S G Sbjct 296 SHIRQHWEIFKPELFEMTEDEWQVAWDSYREFAKAIQYPSTVTKDHGG 343 >sp|Q9HC98|NEK6_HUMAN Serine/threonine-protein kinase Nek6 OS=Homo sapiens OX=9606 GN=NEK6 PE=1 SV=2 Length=313 Score = 219 bits (559), Expect = 9e-63, Method: Composition-based stats. Identities = 62/285 (22%), Positives = 116/285 (41%), Gaps = 30/285 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTL 954 + + +G G F +V Y T + VA+K ++ + R +EI +L+ L Sbjct 45 FQIEKKIGRGQFSEV----YKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQL 100 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICE 1009 H +IIKY + E L +V+E G L + + I + + Q+C Sbjct 101 NHPNIIKYLDSFIEDNE--LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCS 158 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + ++H++ +HRD+ NV + +VK+GD GL + ++ + Sbjct 159 AVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFS---SETTAAHSLVGTPYYMS 215 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE + E + + SD+WS G LYE+ +M + L + +E Sbjct 216 PERIHENGYNFKSDIWSLGCLLYEMAALQSPFYG-------------DKMNLFSLCQKIE 262 Query 1130 RGERLPRP-DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + + P P + ++ L+ C + RP + + K +H Sbjct 263 QCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDIGYVHQVAKQMH 307 Score = 174 bits (441), Expect = 6e-47, Method: Composition-based stats. Identities = 54/333 (16%), Positives = 109/333 (33%), Gaps = 41/333 (12%) Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 +P G ++NL G P R + +G+G + VY+ ++ Sbjct 8 MPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLD 67 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 + E R +K L+ Q++H ++ Sbjct 68 RKTVALKKVQIFEMMDAKARQD------CVK---------------EIGLLKQLNHPNII 106 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDV---WLRRERGHVPMAWKMVVAQQLASALSYLENK 728 + E +V E + G L + ++++ +P QL SA+ ++ ++ Sbjct 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 166 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER----VERIPWLAPECL 784 ++H ++ N+ + G+ +KL D G+G S V +++PE + Sbjct 167 RVMHRDIKPANVFITATGV-------VKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERI 219 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS----EKEHFYQRQHRLPEPSCPQ 840 + D W G L E+ + +K E + Sbjct 220 HENGYNF--KSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEK 277 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 L L S C+ +P QRP + + ++ Sbjct 278 LRELVSMCICPDPHQRPDIGYVHQVAKQMHIWM 310 >sp|Q55GE6|ROCO7_DICDI Probable serine/threonine-protein kinase roco7 OS=Dictyostelium discoideum OX=44689 GN=roco7 PE=3 SV=1 Length=2615 Score = 239 bits (610), Expect = 9e-63, Method: Composition-based stats. Identities = 74/329 (22%), Positives = 138/329 (42%), Gaps = 36/329 (11%) Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920 I L+ L ++ +V LK LG G + V + Sbjct 1739 IIHETLSPRTTKIDIYSLAFEVTFNSNKFSVIPYETLKFGPQLGSGSYANVYRGIW---- 1794 Query 921 DGTGEMVAVKALKADCG----PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976 G VA+K L D G + ++ E I L H + + G L Sbjct 1795 --NGSEVAIKVLNFDDGHANTTEKYREFRNEAHITGELRHANTVSLMGVSLS----PFCL 1848 Query 977 VMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGMAYLHAQH--YIHRDLAARNVLLD 1032 V E + G L ++ + +L A + +GM +LH+ +HRDL + N+LL Sbjct 1849 VTELLQYGDLAKFIRNTAETFSWGTVLKLAIDVAKGMNFLHSCKPMIVHRDLKSANILLG 1908 Query 1033 ----NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 ++ + K+GDFGL+ P G E V+ W APEC+ + ++ D++S+ Sbjct 1909 GSSMDNLVAKVGDFGLS-IKPIGKE---VKGRKVWNWRWLAPECMGDGQYTEKIDIYSYA 1964 Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148 + L+E++T P ++++ + + + + +G R P++CP ++ L+ Sbjct 1965 IVLWEIITR----DLPFEEYVDQLKW------NSIIEDKIMKGLRPTIPNECPPDMKQLI 2014 Query 1149 KNCWETEASFRPTFENLIPILKTVHEKYQ 1177 +CW + RP+F +++ L T+ + + Sbjct 2015 TDCWSGDPKKRPSFNSILERLSTMQKTFN 2043 Score = 209 bits (533), Expect = 2e-53, Method: Composition-based stats. Identities = 63/315 (20%), Positives = 122/315 (39%), Gaps = 49/315 (16%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 + + F + + + LG G+ NVY G Sbjct 1758 FEVTFNSNKFSVIPYETLKFGPQLGSGSYANVYRGIWNGS-------------------- 1797 Query 632 DRGQELRVVLKVLD-----PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 V +KVL+ + + F A + ++ H + + GV + +V Sbjct 1798 ------EVAIKVLNFDDGHANTTEKYREFRNEAHITGELRHANTVSLMGVSL--SPFCLV 1849 Query 687 TEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLAR 744 TE +++G L ++R + +A +A +++L + +VH ++ NILL Sbjct 1850 TELLQYGDLAKFIRNTAETFSWGTVLKLAIDVAKGMNFLHSCKPMIVHRDLKSANILL-- 1907 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERVERI---PWLAPECLPGGANSLSTAMDKWGFG 801 G + + K+ D G+ + + +E + ++ WLAPEC+ G + +D + + Sbjct 1908 -GGSSMDNLVAKVGDFGLSIKPIGKEVKGRKVWNWRWLAPECMGDG--QYTEKIDIYSYA 1964 Query 802 ATLLEICFDGEAPL------QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855 L EI + S E + + +P P + L + C + +P + Sbjct 1965 IVLWEIITRDLPFEEYVDQLKWNSIIEDKIMKGLRPTIPNECPPDMKQLITDCWSGDPKK 2024 Query 856 RPSFRTILRDLTRLQ 870 RPSF +IL L+ +Q Sbjct 2025 RPSFNSILERLSTMQ 2039 >sp|A0A1D6E0S8|WAK17_MAIZE Wall-associated receptor kinase 17 OS=Zea mays OX=4577 GN=WAK17 PE=1 SV=1 Length=856 Score = 234 bits (597), Expect = 9e-63, Method: Composition-based stats. Identities = 71/282 (25%), Positives = 114/282 (40%), Gaps = 18/282 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G G V +VA+K K + EI IL + H +++K Sbjct 533 LGRGGQGTVYKGIL-----PDQTVVAIKKSKV-FDESQVEQFVNEIAILSQIDHPNVVKL 586 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----SIGLAQLLLFAQQICEGMAYLHAQ- 1017 GCC + + LV E++ G+L ++ + L A + + +AYLH+ Sbjct 587 LGCCLET--QVPLLVYEFISNGTLFQHIHNRNATRPLTWEDCLRIAAETADALAYLHSAS 644 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 IHRD+ + N+LLD + + KI DFG +++VP + G + + PE + Sbjct 645 SIPIIHRDIKSSNILLDGNFVAKIADFGASRSVPFDQTHITTLIQG--TIGYLDPEYFQS 702 Query 1076 YKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + SDV+SFGV L ELLT S + P L RL + +E Sbjct 703 SQLTEKSDVYSFGVVLAELLTRQKPISAARPEDSCNLAMHLVVLFNKGRLLQEIEPHILA 762 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 + V L C + RP + +L+ + + Sbjct 763 EAGEDQCYAVAELSVRCLNVKGEERPAMVVVASVLQELRRSF 804 Score = 221 bits (563), Expect = 2e-58, Method: Composition-based stats. Identities = 63/356 (18%), Positives = 129/356 (36%), Gaps = 61/356 (17%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 + ++ LG+G + VY+G L + V +K Sbjct 521 KAATDNYSESRILGRGGQGTVYKGIL-------------------------PDQTVVAIK 555 Query 643 VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 F +++SQ+ H ++ + G C+ ++V E++ +G L + Sbjct 556 KSKVFDESQVEQFVNEIAILSQIDHPNVVKLLGCCLETQVPLLVYEFISNGTLFQHIHNR 615 Query 703 RGHVPMAWK--MVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKL 757 P+ W+ + +A + A AL+YL + + ++H ++ NILL + K+ Sbjct 616 NATRPLTWEDCLRIAAETADALAYLHSASSIPIIHRDIKSSNILLD-------GNFVAKI 668 Query 758 SDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 +D G + + I +L PE ++ L+ D + FG L E+ + Sbjct 669 ADFGASRSVPFDQTHITTLIQGTIGYLDPEYFQ--SSQLTEKSDVYSFGVVLAELLTRQK 726 Query 813 A-----PLQSRSPSEKEHFYQRQHRLPE------------PSCPQLATLTSQCLTYEPTQ 855 P S + + + RL + C +A L+ +CL + + Sbjct 727 PISAARPEDSCNLAMHLVVLFNKGRLLQEIEPHILAEAGEDQCYAVAELSVRCLNVKGEE 786 Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911 RP+ + L L+ D D + + +++L + R + +V Sbjct 787 RPAMVVVASVLQELRRSFTIDQAVGIKDESIQENSEQEEKHLHESRSIPSLQSSEV 842 >sp|Q10056|SHK2_SCHPO Serine/threonine-protein kinase shk2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=shk2 PE=3 SV=1 Length=589 Score = 228 bits (582), Expect = 9e-63, Method: Composition-based stats. Identities = 77/329 (23%), Positives = 135/329 (41%), Gaps = 28/329 (9%) Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899 + ++ + +T P + S T+ R + S + Y Sbjct 261 HVESIMTGKVTKVPVKADSKNTLSRRM---------TDRQALAMLKDSVTSHDPVEYFNV 311 Query 900 IRDLGEGHFGKVSLYCY-DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 LG+G G V L G + VA+K++ C + + EI ++R H + Sbjct 312 KHKLGQGASGSVYLAKVVGGKQLGIFDSVAIKSIDLQCQTR-KELILNEITVMRESIHPN 370 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I+ Y + E+ L +VMEY+ GSL D + + + AQ+ + C+G+ +LHA++ Sbjct 371 IVTYLDSFLVR-ERHLWVVMEYMNAGSLTDIIEKSKLTEAQIARICLETCKGIQHLHARN 429 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ + NVLLDN +KI DFG + R +W APE +K+ ++ Sbjct 430 IIHRDIKSDNVLLDNSGNIKITDFGFCARLS---NRTNKRVTMVGTPYWMAPEVVKQNEY 486 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 D+WS G+ + E++ + L IA+ L+ L+ + Sbjct 487 GTKVDIWSLGIMIIEMI-ENEPPYLREDPIRALYLIAKNGTPTLKKPNLVSKN------- 538 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + +C + FR T L+ Sbjct 539 -----LKSFLNSCLTIDTIFRATAAELLT 562 Score = 184 bits (468), Expect = 7e-48, Method: Composition-based stats. Identities = 54/268 (20%), Positives = 95/268 (35%), Gaps = 40/268 (15%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LGQG +VY ++ V G+ G V +K +D Sbjct 314 KLGQGASGSVYLAKV-------------------VGGKQLGIFDSVAIKSIDLQCQTRKE 354 Query 654 AFYETASLMSQVSHTHLAFVHG-VCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 ++M + H ++ VR +V EY+ G L + E+ + A Sbjct 355 LILNEITVMRESIHPNIVTYLDSFLVRERHLWVVMEYMNAGSLTDII--EKSKLTEAQIA 412 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 + + + +L +N++H ++ N+LL G IK++D G +R Sbjct 413 RICLETCKGIQHLHARNIIHRDIKSDNVLLDNSG-------NIKITDFGFCARLSNRTNK 465 Query 771 --ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 V W+APE + N T +D W G ++E+ + E P P + Sbjct 466 RVTMVGTPYWMAPEVVKQ--NEYGTKVDIWSLGIMIIEMIEN-EPPYLREDPIRALYLIA 522 Query 829 RQHRL----PEPSCPQLATLTSQCLTYE 852 + P L + + CLT + Sbjct 523 KNGTPTLKKPNLVSKNLKSFLNSCLTID 550 >sp|P47735|RLK5_ARATH Receptor-like protein kinase 5 OS=Arabidopsis thaliana OX=3702 GN=RLK5 PE=1 SV=1 Length=999 Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 80/321 (25%), Positives = 129/321 (40%), Gaps = 27/321 (8%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD----- 935 L + +G G GKV GE+VAVK L Sbjct 667 RSFHKLHFSEHEIADCLDEKNVIGFGSSGKVYKVELRG-----GEVVAVKKLNKSVKGGD 721 Query 936 ----CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP 991 +R + E++ L T+ H+ I++ CC G+ L LV EY+P GSL D L Sbjct 722 DEYSSDSLNRDVFAAEVETLGTIRHKSIVRLW-CCCSSGDCKL-LVYEYMPNGSLADVLH 779 Query 992 RHS-----IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFG 1043 +G + L A EG++YLH +HRD+ + N+LLD+D K+ DFG Sbjct 780 GDRKGGVVLGWPERLRIALDAAEGLSYLHHDCVPPIVHRDVKSSNILLDSDYGAKVADFG 839 Query 1044 LAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 +AK G + + APE + + SD++SFGV L EL+T + Sbjct 840 IAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEKSDIYSFGVVLLELVTGKQPTD 899 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 S ++ + L +++ L ++ +V H+ C RP+ Sbjct 900 S-ELGDKDMAKWVCTALDKCGLEPVIDPKLDLKFKEEIS-KVIHIGLLCTSPLPLNRPSM 957 Query 1163 ENLIPILKTVHEKYQGQAPSV 1183 ++ +L+ V +P+ Sbjct 958 RKVVIMLQEVSGAVPCSSPNT 978 Score = 184 bits (466), Expect = 5e-46, Method: Composition-based stats. Identities = 59/330 (18%), Positives = 104/330 (32%), Gaps = 64/330 (19%) Query 509 QQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGAR 568 DG ++ V L L C S+ + A Sbjct 608 DLDGLCRKITRSKNIGYVWILLTIFLLAGLVFVVGIVMFIAKCRKLRALKSSTL----AA 663 Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 + R+ + S H + + + + +G G+ VY+ LR Sbjct 664 SKWRSFHKLHFSEHEIA-DCLDEKNVIGFGSSGKVYKVELRGGE---------------- 706 Query 629 PGRDRGQELRVVLKVLDPSHHDIALA----------FYETASLMSQVSHTHLAFVHGVCV 678 V +K L+ S F + + H + + C Sbjct 707 ---------VVAVKKLNKSVKGGDDEYSSDSLNRDVFAAEVETLGTIRHKSIVRLWCCCS 757 Query 679 RGPENIMVTEYVEHGPLDVWLRRERGH---VPMAWKMVVAQQLASALSYLENK---NLVH 732 G ++V EY+ +G L L +R + ++ +A A LSYL + +VH Sbjct 758 SGDCKLLVYEYMPNGSLADVLHGDRKGGVVLGWPERLRIALDAAEGLSYLHHDCVPPIVH 817 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG--------LGALSREERVERIPWLAPECL 784 +V NILL + K++D G+ + ++APE + Sbjct 818 RDVKSSNILLD-------SDYGAKVADFGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYV 870 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAP 814 ++ D + FG LLE+ G+ P Sbjct 871 --YTLRVNEKSDIYSFGVVLLELV-TGKQP 897 >sp|Q9FIF0|LRK22_ARATH Putative L-type lectin-domain containing receptor kinase II.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK22 PE=3 SV=3 Length=694 Score = 231 bits (588), Expect = 1e-62, Method: Composition-based stats. Identities = 72/301 (24%), Positives = 127/301 (42%), Gaps = 19/301 (6%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 +P + R ++ R LG G FGKV +G +AVK + + Sbjct 356 NEYSPQRYSFRNLYKAIRGFRENRLLGAGGFGKVYKGEL-----PSGTQIAVKRVYHNA- 409 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--- 994 Q + EI + L H+++++ G C +GE L LV +Y+P GSL DYL + Sbjct 410 EQGMKQYAAEIASMGRLRHKNLVQLLGYCRRKGE--LLLVYDYMPNGSLDDYLFNKNKLK 467 Query 995 -IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 + +Q + + + + YLH + +HRD+ A N+LLD D ++GDFGLA+ Sbjct 468 DLTWSQRVNIIKGVASALLYLHEEWEQVVLHRDIKASNILLDADLNGRLGDFGLARFHDR 527 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFL 1109 G R + + APE +D+++FG + E++ P + + Sbjct 528 GENLQATR--VVGTIGYMAPELTAMGVATTKTDIYAFGSFILEVVCGRRPVEPDRPPEQM 585 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 L+ L ++++ K + L C ++ RP+ ++I L Sbjct 586 HLLKWVATCGKRDTLMDVVDSKL-GDFKAKEAKLLLKLGMLCSQSNPESRPSMRHIIQYL 644 Query 1170 K 1170 + Sbjct 645 E 645 Score = 221 bits (563), Expect = 2e-59, Method: Composition-based stats. Identities = 63/304 (21%), Positives = 114/304 (38%), Gaps = 62/304 (20%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 + LG G VY+G L ++ +K + + Sbjct 375 FRENRLLGAGGFGKVYKGEL-------------------------PSGTQIAVKRVYHNA 409 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 + + M ++ H +L + G C R E ++V +Y+ +G LD +L + + Sbjct 410 EQGMKQYAAEIASMGRLRHKNLVQLLGYCRRKGELLLVYDYMPNGSLDDYLFNKNKLKDL 469 Query 709 AW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 W ++ + + +ASAL YL + ++H ++ NILL +L D G+ Sbjct 470 TWSQRVNIIKGVASALLYLHEEWEQVVLHRDIKASNILLD-------ADLNGRLGDFGLA 522 Query 764 LGA-----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 L V I ++APE G +T D + FG+ +LE+ G P++ Sbjct 523 RFHDRGENLQATRVVGTIGYMAPELTAMGVA--TTKTDIYAFGSFILEVVC-GRRPVEPD 579 Query 819 SPSEKEHF------YQRQHRLPEPSCPQLATLTSQ-----------CLTYEPTQRPSFRT 861 P E+ H ++ L + +L ++ C P RPS R Sbjct 580 RPPEQMHLLKWVATCGKRDTLMDVVDSKLGDFKAKEAKLLLKLGMLCSQSNPESRPSMRH 639 Query 862 ILRD 865 I++ Sbjct 640 IIQY 643 >sp|Q9FLZ3|KIN12_ARATH SNF1-related protein kinase catalytic subunit alpha KIN12 OS=Arabidopsis thaliana OX=3702 GN=KIN12 PE=2 SV=1 Length=494 Score = 225 bits (574), Expect = 1e-62, Method: Composition-based stats. Identities = 75/274 (27%), Positives = 113/274 (41%), Gaps = 29/274 (11%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILR 952 + + LG G F KV L + TG VA+K L ++EI ILR Sbjct 17 PNYRIGKTLGHGSFAKVKLALHVA----TGHKVAIKILNRSKIKNMGIEIKVQREIKILR 72 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGM 1011 L H HII+ E + + +VMEYV G L DY+ + + + QQI G+ Sbjct 73 FLMHPHIIRQYEVIETPND--IYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGV 130 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 Y H +HRDL NVLLD+ +KI DFGL+ + +G + ++ SP + APE Sbjct 131 EYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDG---HFLKTSCGSPN-YAAPE 186 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + D+WS GV LY LL + + E ++RG Sbjct 187 VISGKPYGPDVDIWSCGVILYALLCGTLPFDDE---------------NIPNVFEKIKRG 231 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P+ L+ + + R + + Sbjct 232 M-YTLPNHLSHFARDLIPRMLMVDPTMRISITEI 264 Score = 177 bits (448), Expect = 5e-46, Method: Composition-based stats. Identities = 55/326 (17%), Positives = 96/326 (29%), Gaps = 40/326 (12%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 LG G+ V G +V +K+L+ S Sbjct 18 NYRIGKTLGHGSFAKVKLALHVATGH------------------------KVAIKILNRS 53 Query 648 ---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + I + ++ + H H+ + V + +V EYV+ G L ++ E+G Sbjct 54 KIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYI-VEKG 112 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + QQ+ S + Y +VH ++ N+LL IK+ D G+ Sbjct 113 KLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQC-------NIKIVDFGLSN 165 Query 765 GALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + + APE + G +D W G L + P+ Sbjct 166 VMHDGHFLKTSCGSPNYAAPEVISG--KPYGPDVDIWSCGVILYALLCGTLPFDDENIPN 223 Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 E + + LP L + L +PT R S I + L + Sbjct 224 VFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPL 283 Query 882 PDSPASDPTVFHKRYLKKIRDLGEGH 907 + H Sbjct 284 DTIDQAKKIEEEIIQNVVNIGFDRNH 309 >sp|Q6K4T4|SERK4_ORYSJ LRR receptor kinase SERK2 OS=Oryza sativa subsp. japonica OX=39947 GN=SERK4 PE=3 SV=1 Length=607 Score = 229 bits (583), Expect = 1e-62, Method: Composition-based stats. Identities = 75/328 (23%), Positives = 127/328 (39%), Gaps = 20/328 (6%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 + + + + + A + LG+G FGKV Sbjct 241 CKGRRKSHLREVFVDVAGEDDRRIAFGQLKRFAWRELQIATDNFSERNVLGQGGFGKVYK 300 Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 G +AVK L P + + +E++++ H +++K G C Q E+ Sbjct 301 GVL-----PDGTKIAVKRLTDYESPGGEAAFLREVELISVAVHRNLLKLIGFCTTQTER- 354 Query 974 LQLVMEYVPLGS----LRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLA 1025 LV ++ S LRD+ P + + A G+ YLH IHRD+ Sbjct 355 -LLVYPFMQNLSVAYRLRDFKPGEPVLNWPERKRVAIGTARGLEYLHEHCNPKIIHRDVK 413 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 A NVLLD D +GDFGLAK V + V + APE L K +DV+ Sbjct 414 AANVLLDEDFEPVVGDFGLAKLV--DVQKTSVTTQVRGTMGHIAPEYLSTGKSSERTDVF 471 Query 1086 SFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 +G+ L EL+T D S+ + L+ + +L +++R D+ Sbjct 472 GYGIMLLELVTGQRAIDFSRLEEEDDVLLLDHVKKLQREGQLGSIVDRNLNQNYDDEEVE 531 Query 1143 EVYHLMKNCWETEASFRPTFENLIPILK 1170 + + C ++ RP+ ++ +L+ Sbjct 532 MMIQIALLCTQSSPEDRPSMSEVVRMLE 559 Score = 185 bits (470), Expect = 4e-48, Method: Composition-based stats. Identities = 63/362 (17%), Positives = 113/362 (31%), Gaps = 67/362 (19%) Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + ++ + ++ + LGQG VY+G L Sbjct 268 QLKRFAWRELQIATDNFSERNVLGQGGFGKVYKGVLPDG--------------------- 306 Query 633 RGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 ++ +K L D AF L+S H +L + G C E ++V +++ Sbjct 307 ----TKIAVKRLTDYESPGGEAAFLREVELISVAVHRNLLKLIGFCTTQTERLLVYPFMQ 362 Query 692 HGPLDVWLRRERGHVP---MAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745 + + LR + P + VA A L YL ++H +V N+LL Sbjct 363 NLSVAYRLRDFKPGEPVLNWPERKRVAIGTARGLEYLHEHCNPKIIHRDVKAANVLLDED 422 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800 + D G+ ++ V + +APE L G + S D +G+ Sbjct 423 FEPV-------VGDFGLAKLVDVQKTSVTTQVRGTMGHIAPEYLSTGKS--SERTDVFGY 473 Query 801 GATLLEICFDGEAPLQSRSPSE--------KEHFYQRQ-----------HRLPEPSCPQL 841 G LLE+ A SR E + + + + Sbjct 474 GIMLLELVTGQRAIDFSRLEEEDDVLLLDHVKKLQREGQLGSIVDRNLNQNYDDEEVEMM 533 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901 + C P RPS ++R L + + + +R+ Sbjct 534 IQIALLCTQSSPEDRPSMSEVVRMLEGEGLAERWEEWQQVEVTRRQEYERMQRRFDWGED 593 Query 902 DL 903 + Sbjct 594 SV 595 >sp|Q9C7S5|PSYR1_ARATH Tyrosine-sulfated glycopeptide receptor 1 OS=Arabidopsis thaliana OX=3702 GN=PSY1R PE=1 SV=1 Length=1095 Score = 236 bits (603), Expect = 1e-62, Method: Composition-based stats. Identities = 66/286 (23%), Positives = 118/286 (41%), Gaps = 19/286 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V D G +AVK L D G + +K E+++L HE+++ Sbjct 809 IGCGGFGLVYKATLD-----NGTKLAVKKLTGDYGMMEKE-FKAEVEVLSRAKHENLVAL 862 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLH-- 1015 +G C + L+ ++ GSL +L + + + L + G+AY+H Sbjct 863 QGYCVHDSAR--ILIYSFMENGSLDYWLHENPEGPAQLDWPKRLNIMRGASSGLAYMHQI 920 Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H +HRD+ + N+LLD + + DFGL++ + + V + + + PE + Sbjct 921 CEPHIVHRDIKSSNILLDGNFKAYVADFGLSRLILPYRTH--VTTELVGTLGYIPPEYGQ 978 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + DV+SFGV + ELLT + P EL+ + E+ + R Sbjct 979 AWVATLRGDVYSFGVVMLELLTGKRPMEVFRPKMSRELVAWVHTMKRDGKPEEVFDTLLR 1038 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 ++ V + C RP + ++ LK + + Sbjct 1039 ESGNEEAMLRVLDIACMCVNQNPMKRPNIQQVVDWLKNIEAEKNQN 1084 Score = 203 bits (517), Expect = 5e-52, Method: Composition-based stats. Identities = 65/344 (19%), Positives = 128/344 (37%), Gaps = 67/344 (19%) Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615 + S +++ +R + L + +L +Q + +G G VY+ L Sbjct 773 KDISLVLLFGNSRYEVKDLTIFELLK---ATDNFSQANIIGCGGFGLVYKATL------- 822 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675 D G +L +K L + + F ++S+ H +L + G Sbjct 823 ----------------DNGTKL--AVKKLTGDYGMMEKEFKAEVEVLSRAKHENLVALQG 864 Query 676 VCVRGPENIMVTEYVEHGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLE---NKN 729 CV I++ ++E+G LD WL G + W ++ + + +S L+Y+ + Sbjct 865 YCVHDSARILIYSFMENGSLDYWLHENPEGPAQLDWPKRLNIMRGASSGLAYMHQICEPH 924 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS-----REERVERIPWLAPECL 784 +VH ++ NILL A ++D G+ L E V + ++ PE Sbjct 925 IVHRDIKSSNILLDGNFKAY-------VADFGLSRLILPYRTHVTTELVGTLGYIPPEY- 976 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP----- 839 G A + D + FG +LE+ G+ P++ P H + P Sbjct 977 -GQAWVATLRGDVYSFGVVMLELL-TGKRPMEVFRPKMSRELVAWVHTMKRDGKPEEVFD 1034 Query 840 -------------QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 ++ + C+ P +RP+ + ++ L ++ Sbjct 1035 TLLRESGNEEAMLRVLDIACMCVNQNPMKRPNIQQVVDWLKNIE 1078 >sp|Q9CAL3|CRK2_ARATH Cysteine-rich receptor-like protein kinase 2 OS=Arabidopsis thaliana OX=3702 GN=CRK2 PE=1 SV=1 Length=649 Score = 229 bits (585), Expect = 1e-62, Method: Composition-based stats. Identities = 74/290 (26%), Positives = 123/290 (42%), Gaps = 26/290 (9%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-GWKQEIDILRTLY 955 LG+G FG V G +AVK L +HR+ + E++++ T+ Sbjct 325 FDNANKLGQGGFGTVYKGVL-----PDGRDIAVKRL--FFNNRHRATDFYNEVNMISTVE 377 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGM 1011 H+++++ GC E LV EY+ SL ++ ++ + EG+ Sbjct 378 HKNLVRLLGCSCSGPES--LLVYEYLQNKSLDRFIFDVNRGKTLDWQRRYTIIVGTAEGL 435 Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 YLH Q IHRD+ A N+LLD+ KI DFGLA++ + + G + + Sbjct 436 VYLHEQSSVKIIHRDIKASNILLDSKLQAKIADFGLARSFQDDKSHISTAIAG--TLGYM 493 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE-LIGIAQGQMTVLRLTEL 1127 APE L + DV+SFGV + E++T +++S + + + LI A L ++ Sbjct 494 APEYLAHGQLTEMVDVYSFGVLVLEIVTGKQNTKSKMSDYSDSLITEAWKHFQSGELEKI 553 Query 1128 LERGERLP------RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + K V + C + S RP L+ +LK Sbjct 554 YDPNLDWKSQYDSHIIKKEIARVVQIGLLCTQEIPSLRPPMSKLLHMLKN 603 Score = 214 bits (544), Expect = 3e-57, Method: Composition-based stats. Identities = 58/260 (22%), Positives = 101/260 (39%), Gaps = 45/260 (17%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +LN + + + LGQG VY+G L Sbjct 307 KDSSLNFKYSTLEK-ATGSFDNANKLGQGGFGTVYKGVL-------------------PD 346 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 GRD + +K L ++ A FY +++S V H +L + G GPE+++V EY Sbjct 347 GRD------IAVKRLFFNNRHRATDFYNEVNMISTVEHKNLVRLLGCSCSGPESLLVYEY 400 Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744 +++ LD ++ + W + + A L YL + ++H ++ NILL Sbjct 401 LQNKSLDRFIFDVNRGKTLDWQRRYTIIVGTAEGLVYLHEQSSVKIIHRDIKASNILLDS 460 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWG 799 A K++D G+ + + + ++APE L G L+ +D + Sbjct 461 KLQA-------KIADFGLARSFQDDKSHISTAIAGTLGYMAPEYLAHG--QLTEMVDVYS 511 Query 800 FGATLLEICFDGEAPLQSRS 819 FG +LEI + S Sbjct 512 FGVLVLEIVTGKQNTKSKMS 531 >sp|Q8RY65|NIK2_ARATH Protein NSP-INTERACTING KINASE 2 OS=Arabidopsis thaliana OX=3702 GN=NIK2 PE=1 SV=1 Length=635 Score = 229 bits (584), Expect = 1e-62, Method: Composition-based stats. Identities = 67/311 (22%), Positives = 120/311 (39%), Gaps = 15/311 (5%) Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGE 925 + N ++ N +G+G FG V C G Sbjct 281 FFDINEQNKEEMCLGNLRRFNFKELQSATSNFSSKNLVGKGGFGNVYKGCL-----HDGS 335 Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 ++AVK LK ++ E++++ H ++++ G C E+ LV Y+ GS Sbjct 336 IIAVKRLKDINNGGGEVQFQTELEMISLAVHRNLLRLYGFCTTSSER--LLVYPYMSNGS 393 Query 986 LRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGD 1041 + L + + A G+ YLH Q IHRD+ A N+LLD+ +GD Sbjct 394 VASRLKAKPVLDWGTRKRIALGAGRGLLYLHEQCDPKIIHRDVKAANILLDDYFEAVVGD 453 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS- 1100 FGLAK + + V V APE L + +DV+ FG+ L EL+T + Sbjct 454 FGLAKLLDHEESH--VTTAVRGTVGHIAPEYLSTGQSSEKTDVFGFGILLLELITGLRAL 511 Query 1101 -SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 + ++ + +L +++++ + E+ + C + R Sbjct 512 EFGKAANQRGAILDWVKKLQQEKKLEQIVDKDLKSNYDRIEVEEMVQVALLCTQYLPIHR 571 Query 1160 PTFENLIPILK 1170 P ++ +L+ Sbjct 572 PKMSEVVRMLE 582 Score = 183 bits (465), Expect = 3e-47, Method: Composition-based stats. Identities = 63/320 (20%), Positives = 113/320 (35%), Gaps = 64/320 (20%) Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 NL + +F + + + +G+G NVY+G L Sbjct 296 NLRRFNFKELQSATSNFSSKNLVGKGGFGNVYKGCLHDGSI------------------- 336 Query 633 RGQELRVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 + +K L ++ + F ++S H +L ++G C E ++V Y+ Sbjct 337 ------IAVKRLKDINNGGGEVQFQTELEMISLAVHRNLLRLYGFCTTSSERLLVYPYMS 390 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748 +G + L+ + + + +A L YL + ++H +V NILL A Sbjct 391 NGSVASRLKA-KPVLDWGTRKRIALGAGRGLLYLHEQCDPKIIHRDVKAANILLDDYFEA 449 Query 749 EGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 + D G+ E V + +APE L G + S D +GFG Sbjct 450 V-------VGDFGLAKLLDHEESHVTTAVRGTVGHIAPEYLSTGQS--SEKTDVFGFGIL 500 Query 804 LLEICF------DGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT------------LT 845 LLE+ G+A Q + + Q++ +L + L + + Sbjct 501 LLELITGLRALEFGKAANQRGAILDWVKKLQQEKKLEQIVDKDLKSNYDRIEVEEMVQVA 560 Query 846 SQCLTYEPTQRPSFRTILRD 865 C Y P RP ++R Sbjct 561 LLCTQYLPIHRPKMSEVVRM 580 >sp|Q9FN37|PSKR2_ARATH Phytosulfokine receptor 2 OS=Arabidopsis thaliana OX=3702 GN=PSKR2 PE=1 SV=1 Length=1036 Score = 236 bits (602), Expect = 1e-62, Method: Composition-based stats. Identities = 76/330 (23%), Positives = 131/330 (40%), Gaps = 19/330 (6%) Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911 + TI L P + + + + + + +G G FG V Sbjct 709 DRINDVDEETISGVSKALGPSKIVLFHSCGCKDLSVEELLKSTNNFSQANIIGCGGFGLV 768 Query 912 SLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 + G AVK L DCG R ++ E++ L H++++ +G C+ + Sbjct 769 YKANF-----PDGSKAAVKRLSGDCGQMERE-FQAEVEALSRAEHKNLVSLQGYCKHGND 822 Query 972 KSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLH---AQHYIHRD 1023 + L+ ++ GSL +L ++ L AQ G+AYLH + IHRD Sbjct 823 R--LLIYSFMENGSLDYWLHERVDGNMTLIWDVRLKIAQGAARGLAYLHKVCEPNVIHRD 880 Query 1024 LAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASD 1083 + + N+LLD + DFGLA+ + + V D + + PE + D Sbjct 881 VKSSNILLDEKFEAHLADFGLARLLRPYDTH--VTTDLVGTLGYIPPEYSQSLIATCRGD 938 Query 1084 VWSFGVTLYELLTHCDSSQSPPTKF-LELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 V+SFGV L EL+T + K +L+ R EL++ R ++ Sbjct 939 VYSFGVVLLELVTGRRPVEVCKGKSCRDLVSRVFQMKAEKREAELIDTTIRENVNERTVL 998 Query 1143 EVYHLMKNCWETEASFRPTFENLIPILKTV 1172 E+ + C + E RP E ++ L+ + Sbjct 999 EMLEIACKCIDHEPRRRPLIEEVVTWLEDL 1028 Score = 206 bits (523), Expect = 7e-53, Method: Composition-based stats. Identities = 59/322 (18%), Positives = 113/322 (35%), Gaps = 64/322 (20%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +Q + +G G VY+ + + +K L Sbjct 750 STNNFSQANIIGCGGFGLVYKA-------------------------NFPDGSKAAVKRL 784 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-R 703 + F +S+ H +L + G C G + +++ ++E+G LD WL Sbjct 785 SGDCGQMEREFQAEVEALSRAEHKNLVSLQGYCKHGNDRLLIYSFMENGSLDYWLHERVD 844 Query 704 GHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 G++ + W ++ +AQ A L+YL N++H +V NILL A L+ Sbjct 845 GNMTLIWDVRLKIAQGAARGLAYLHKVCEPNVIHRDVKSSNILLDEKFEAH-------LA 897 Query 759 DPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 D G+ + V + ++ PE + D + FG LLE+ G Sbjct 898 DFGLARLLRPYDTHVTTDLVGTLGYIPPEYSQSLIA--TCRGDVYSFGVVLLELV-TGRR 954 Query 814 PLQSRSPSEKEHFYQRQHRLP------------------EPSCPQLATLTSQCLTYEPTQ 855 P++ R ++ E + ++ + +C+ +EP + Sbjct 955 PVEVCKGKSCRDLVSRVFQMKAEKREAELIDTTIRENVNERTVLEMLEIACKCIDHEPRR 1014 Query 856 RPSFRTILRDLTRLQPHNLADV 877 RP ++ L L ++ Sbjct 1015 RPLIEEVVTWLEDLPMESVQQQ 1036 >sp|Q6X4A2|CIPKV_ORYSJ CBL-interacting protein kinase 31 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK31 PE=1 SV=1 Length=449 Score = 224 bits (570), Expect = 1e-62, Method: Composition-based stats. Identities = 65/290 (22%), Positives = 117/290 (40%), Gaps = 35/290 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959 +GEG F KV N E VA+K L + +HR ++EI ++ + H ++ Sbjct 25 TIGEGTFAKVRF----AKNTENDEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHPNV 80 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ + + +V+EYV G L + + + + + QQ+ + Y H++ Sbjct 81 VRLFEVM--GSKARIFIVLEYVTGGELFEIIATNGRLKEEEARKYFQQLINAVDYCHSRG 138 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N+LLD +K+ DFGL+ + + +P + APE +++ + Sbjct 139 VYHRDLKLENLLLDASGNLKVSDFGLSALTEQVKADGLLHTTCGTPN-YVAPEVIEDRGY 197 Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 A+D+WS GV LY LL + ++ L + + + P Sbjct 198 DGAAADIWSCGVILYVLLAGFLPFEDD---------------NIIALYKKISEA-QFTCP 241 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAPSVFS 1185 L+ + + R T ++ P K +G P VF Sbjct 242 SWFSTGAKKLITRILDPNPTTRITISQILEDPWFK------KGYKPPVFD 285 Score = 172 bits (435), Expect = 9e-45, Method: Composition-based stats. Identities = 57/320 (18%), Positives = 97/320 (30%), Gaps = 44/320 (14%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 LS RV + E+ +G+GT V ++ Sbjct 9 LSPKVKRRVGKYEL--GRTIGEGTFAKV------------------------RFAKNTEN 42 Query 636 ELRVVLKVLDPSHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 + V +K+LD + M V H ++ + V +V EYV Sbjct 43 DEPVAIKILDKEKVQKHRLVEQIRREICTMKLVKHPNVVRLFEVMGSKARIFIVLEYVTG 102 Query 693 GPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTS 752 G L + G + QQL +A+ Y ++ + H ++ N+LL S Sbjct 103 GELFEIIATN-GRLKEEEARKYFQQLINAVDYCHSRGVYHRDLKLENLLLD-------AS 154 Query 753 PFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 +K+SD G+ + ++APE + A D W G L Sbjct 155 GNLKVSDFGLSALTEQVKADGLLHTTCGTPNYVAPEVIEDRGYD-GAAADIWSCGVILYV 213 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 + + + + Q P L ++ L PT R + IL D Sbjct 214 LLAGFLPFEDDNIIALYKKISEAQFTCPSWFSTGAKKLITRILDPNPTTRITISQILEDP 273 Query 867 TRLQPHNLADVLTVNPDSPA 886 + + S Sbjct 274 WFKKGYKPPVFDEKYETSFD 293 >sp|O14305|SID1_SCHPO Serine/threonine-protein kinase sid1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=sid1 PE=1 SV=1 Length=471 Score = 224 bits (572), Expect = 1e-62, Method: Composition-based stats. Identities = 64/280 (23%), Positives = 121/280 (43%), Gaps = 25/280 (9%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 + +R LG G FG V + + +G+++A+K + + G + +QE+ Sbjct 1 MYPLNANSYTLLRKLGSGSFGVV----WKARENVSGDIIAIKQIDLETGIDDITDIEQEV 56 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQIC 1008 +L ++I+Y GC D +L ++ME++ GS+ L + + + +++ Sbjct 57 FMLSNCNSSNVIQYYGCFVDG--YTLWILMEHMDGGSVSGLLKMGRLNEQVISIILREVL 114 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 G+ YLH Q+ IHRD+ A N+LL + VK+ DFG+A + R FW Sbjct 115 YGLNYLHGQNKIHRDIKAANILLSSSTGNVKLADFGVAAQLSNAASR---RHTFVGTPFW 171 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE +++ + A+D+WS G+T E+ + M +R+ Sbjct 172 MAPEVIQQTSYGLAADIWSLGITAIEMANGIPP---------------RATMHPMRVIFE 216 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + E D + C + + R + + L+ Sbjct 217 IPQSEPPKLDDHFSPTFRDFVSCCLDLNPNMRWSAKELLQ 256 Score = 192 bits (488), Expect = 2e-51, Method: Composition-based stats. Identities = 59/291 (20%), Positives = 112/291 (38%), Gaps = 42/291 (14%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 ++ T L LG G+ V++ R V G + +K Sbjct 4 LNANSYTLLRKLGSGSFGVVWKARENVSGD------------------------IIAIKQ 39 Query 644 LD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 +D + D + ++S + +++ +G V G ++ E+++ G + L+ Sbjct 40 IDLETGIDDITDIEQEVFMLSNCNSSNVIQYYGCFVDGYTLWILMEHMDGGSVSGLLKM- 98 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG- 761 G + ++ +++ L+YL +N +H ++ NILL+ ++ +KL+D G Sbjct 99 -GRLNEQVISIILREVLYGLNYLHGQNKIHRDIKAANILLSS------STGNVKLADFGV 151 Query 762 ---VGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + A R V W+APE + S A D W G T +E+ +G P + Sbjct 152 AAQLSNAASRRHTFVGTPFWMAPEVIQQ--TSYGLAADIWSLGITAIEMA-NGIPPRATM 208 Query 819 SPSEKEHFYQRQ--HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 P + +L + P S CL P R S + +L+ Sbjct 209 HPMRVIFEIPQSEPPKLDDHFSPTFRDFVSCCLDLNPNMRWSAKELLQHPF 259 >sp|Q00372|SNF1_CANGA Carbon catabolite-derepressing protein kinase OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=SNF1 PE=3 SV=2 Length=612 Score = 228 bits (582), Expect = 1e-62, Method: Composition-based stats. Identities = 74/276 (27%), Positives = 114/276 (41%), Gaps = 31/276 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG--WKQEIDILRT 953 + ++ LGEG FGKV L + TG+ VA+K + + ++EI LR Sbjct 38 NYQIVKTLGEGSFGKVKLAY----HVTTGQKVALKIINKKVLAKSDMQGRIEREISYLRL 93 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012 L H HIIK + + E + +V+EY L DY+ R+ + + F QQI + Sbjct 94 LRHPHIIKLYDVIKSKDE--IIMVIEYAGN-ELFDYIVQRNKMSEQEARRFFQQIISAVE 150 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Y H +HRDL N+LLD VKI DFGL+ + +G+ ++ SP + APE Sbjct 151 YCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGN---FLKTSCGSPN-YAAPEV 206 Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + DVWS GV LY +L ++ L + + G Sbjct 207 ISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDE---------------SIPVLFKNISNG 251 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P L+K R + ++ Sbjct 252 V-YTLPKFLSPGASDLIKRMLIVNPLNRISIHEIMQ 286 Score = 180 bits (457), Expect = 3e-46, Method: Composition-based stats. Identities = 53/287 (18%), Positives = 95/287 (33%), Gaps = 40/287 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + LG+G+ V G +V LK+++ Sbjct 38 NYQIVKTLGEGSFGKVKLAYHVTTGQ------------------------KVALKIINKK 73 Query 648 ---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D+ S + + H H+ ++ V E IMV EY + L ++ +R Sbjct 74 VLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGN-ELFDYI-VQRN 131 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + QQ+ SA+ Y +VH ++ N+LL +K++D G+ Sbjct 132 KMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDE-------HLNVKIADFGLSN 184 Query 765 GALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + + APE + G + +D W G L + P Sbjct 185 IMTDGNFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYVMLCRRLPFDDESIPV 243 Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 ++ + LP+ P + L + L P R S I++D Sbjct 244 LFKNISNGVYTLPKFLSPGASDLIKRMLIVNPLNRISIHEIMQDEWF 290 >sp|Q9UEW8|STK39_HUMAN STE20/SPS1-related proline-alanine-rich protein kinase OS=Homo sapiens OX=9606 GN=STK39 PE=1 SV=3 Length=545 Score = 227 bits (578), Expect = 1e-62, Method: Composition-based stats. Identities = 71/290 (24%), Positives = 118/290 (41%), Gaps = 24/290 (8%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + + +G G V P E VA+K + + +EI Sbjct 56 WPICRDAYELQEVIGSGATAVVQAALCKPRQ----ERVAIKRINLEKCQTSMDELLKEIQ 111 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---------RHSIGLAQL 1000 + H +++ Y + E L LVM+ + GS+ D + + A + Sbjct 112 AMSQCSHPNVVTYYTSFVVKDE--LWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAII 169 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--VR 1058 +++ EG+ YLH IHRDL A N+LL D V+I DFG++ + G + R VR Sbjct 170 ATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVR 229 Query 1059 EDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 + W APE +++ + + +D+WSFG+T EL T P + ++ + Sbjct 230 KTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTL--- 286 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 Q L +E E + K L+ C + + S RPT L+ Sbjct 287 QNDPPTLETGVEDKEMM---KKYGKSFRKLLSLCLQKDPSKRPTAAELLK 333 Score = 173 bits (439), Expect = 2e-44, Method: Composition-based stats. Identities = 60/354 (17%), Positives = 122/354 (34%), Gaps = 52/354 (15%) Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 + ++ RV +K ++ ++ + MSQ SH ++ + V E +V + + Sbjct 83 KPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLS 142 Query 692 HGPLDVWLR-------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 G + ++ + G + A + +++ L YL +H ++ NILL Sbjct 143 GGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGE 202 Query 745 LGLAEGTSPFIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAM 795 G ++++D GV + R+ V W+APE + Sbjct 203 DG-------SVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKA 254 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-----------HRLPEPSCPQLATL 844 D W FG T +E+ G AP P + + + + L Sbjct 255 DMWSFGITAIELA-TGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKL 313 Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 S CL +P++RP+ +L+ + + P + + + Sbjct 314 LSLCLQKDPSKRPTAAELLKCKFF---QKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGS 370 Query 905 EGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 GH K ++ ++D E + ++ + QE R + E+ Sbjct 371 SGHLHKTEDGDWEWSDDEMDEK----------SEEGKAAFSQEKS--RRVKEEN 412 >sp|Q19238|YS3J_CAEEL Putative tyrosine-protein kinase F09A5.2 OS=Caenorhabditis elegans OX=6239 GN=F09A5.2 PE=3 SV=3 Length=867 Score = 234 bits (596), Expect = 1e-62, Method: Composition-based stats. Identities = 89/357 (25%), Positives = 145/357 (41%), Gaps = 56/357 (16%) Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY--LKKIRD 902 + + + + N + ++ D + +++ Sbjct 413 MRKKFNKDVENGSCKELNTQKWSHFASANNYMDIQALANANKKDIWEIDTKNLLVQEDHL 472 Query 903 LGEGHFGKVSLYCYDPT------NDGTGEMV----------AVKALKADCGPQHRSGWKQ 946 LG G F V N+ V A+K L A Q+ + Sbjct 473 LGNGAFANVYKGIVKGKIPLLVVNNSLNMTVESENNGHYEAAIKKLPAHADEQNHLDFFH 532 Query 947 EIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------- 994 EID ++ L +H H+I GC + E +V+EY G L +L RH Sbjct 533 EIDFMKRLGHHPHVISMLGCVSNPYEP--LIVVEYCARGDLLKFLRRHKDYVLMNKTDDC 590 Query 995 -------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 + + L+ A Q+ +GM+YL ++++IHRDLAARN+LL K+ DFGL + Sbjct 591 PIEADMCLRIKDLVSIAWQVADGMSYLASKNFIHRDLAARNILLTKSLTAKVSDFGLCRY 650 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 + + G P+ W + E LK Y+F +DVWSFGV L+E+ + D Sbjct 651 M---DSALYTAKGGRLPIKWMSVEALKLYEFSTKTDVWSFGVLLFEIFSMGD-------- 699 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + + + + E L G RL +P KCP E++++M+ CW + RP F Sbjct 700 ------VPYPTIQQVDMLEHLLAGGRLSQPLKCPNEIFNIMQKCWAEKPEDRPEFNE 750 Score = 225 bits (573), Expect = 1e-59, Method: Composition-based stats. Identities = 76/321 (24%), Positives = 127/321 (40%), Gaps = 39/321 (12%) Query 575 NLSQLSFHRVDQKEI--TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 N ++ +D K + + LG G NVY+G ++ G +++ + + Sbjct 451 NANKKDIWEIDTKNLLVQEDHLLGNGAFANVYKGIVK----GKIPLLVVNNSLNMTVESE 506 Query 633 RGQELRVVLKVLDP-SHHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690 +K L + L F+ M ++ H H+ + G E ++V EY Sbjct 507 NNGHYEAAIKKLPAHADEQNHLDFFHEIDFMKRLGHHPHVISMLGCVSNPYEPLIVVEYC 566 Query 691 EHGPLDVWLRRERGHVPMAW----------------KMVVAQQLASALSYLENKNLVHGN 734 G L +LRR + +V M + +A Q+A +SYL +KN +H + Sbjct 567 ARGDLLKFLRRHKDYVLMNKTDDCPIEADMCLRIKDLVSIAWQVADGMSYLASKNFIHRD 626 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER----IPWLAPECLPGGANS 790 + RNILL + S K+SD G+ S + I W++ E L Sbjct 627 LAARNILLTK-------SLTAKVSDFGLCRYMDSALYTAKGGRLPIKWMSVEALK--LYE 677 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQC 848 ST D W FG L EI G+ P + + RL +P CP + + +C Sbjct 678 FSTKTDVWSFGVLLFEIFSMGDVPYPTIQQVDMLEHLLAGGRLSQPLKCPNEIFNIMQKC 737 Query 849 LTYEPTQRPSFRTILRDLTRL 869 +P RP F + ++T + Sbjct 738 WAEKPEDRPEFNEMRGEITVM 758 >sp|P51956|NEK3_HUMAN Serine/threonine-protein kinase Nek3 OS=Homo sapiens OX=9606 GN=NEK3 PE=1 SV=2 Length=506 Score = 226 bits (575), Expect = 1e-62, Method: Composition-based stats. Identities = 67/277 (24%), Positives = 119/277 (43%), Gaps = 27/277 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 +R +GEG FG+ L ++ + +M A+K ++ + ++E +L Sbjct 1 MDDYMVLRMIGEGSFGRALLVQHE----SSNQMFAMKEIRLPKSFSNTQNSRKEAVLLAK 56 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEG 1010 + H +I+ +K E E L +VMEY G L + + +L + Q+C G Sbjct 57 MKHPNIVAFKESFE--AEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLG 114 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 + ++H + +HRD+ ++N+ L + VK+GDFG A+ + + ++ P Sbjct 115 VNHIHKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACT---YVGTPYYVPP 171 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E + + SD+WS G LYEL T Q+ K L L + + Sbjct 172 EIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWKNLIL---------------KVCQ 216 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 G P P E+ L+K ++ S RP+ L+ Sbjct 217 GCISPLPSHYSYELQFLVKQMFKRNPSHRPSATTLLS 253 Score = 155 bits (392), Expect = 1e-38, Method: Composition-based stats. Identities = 46/284 (16%), Positives = 92/284 (32%), Gaps = 40/284 (14%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + L +G+G+ + + +K + Sbjct 1 MDDYMVLRMIGEGSFGR------------------------ALLVQHESSNQMFAMKEIR 36 Query 646 -PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 P + A L++++ H ++ +V EY + G L +++++G Sbjct 37 LPKSFSNTQNSRKEAVLLAKMKHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKG 96 Query 705 HV-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + P + Q+ ++++ K ++H ++ +NI L + G +KL D G Sbjct 97 KLFPEDMILNWFTQMCLGVNHIHKKRVLHRDIKSKNIFLTQNG-------KVKLGDFGSA 149 Query 764 LGALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + V ++ PE + D W G L E+C + Sbjct 150 RLLSNPMAFACTYVGTPYYVPPEIWEN--LPYNNKSDIWSLGCILYELCTLKHPFQANSW 207 Query 820 PSEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 + Q LP +L L Q P+ RPS T+ Sbjct 208 KNLILKVCQGCISPLPSHYSYELQFLVKQMFKRNPSHRPSATTL 251 >sp|Q9FII5|TDR_ARATH Leucine-rich repeat receptor-like protein kinase TDR OS=Arabidopsis thaliana OX=3702 GN=TDR PE=1 SV=1 Length=1041 Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 74/301 (25%), Positives = 125/301 (42%), Gaps = 28/301 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-----SGWKQEIDILRTLYHE 957 LG G G V GE++AVK L + SG E+D+L + H Sbjct 725 LGMGSTGTVYKA-----EMPNGEIIAVKKLWGKNKENGKIRRRKSGVLAEVDVLGNVRHR 779 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG------LAQLLLFAQQICEGM 1011 +I++ GCC ++ L+ EY+P GSL D L L A + +G+ Sbjct 780 NIVRLLGCCTNRD--CTMLLYEYMPNGSLDDLLHGGDKTMTAAAEWTALYQIAIGVAQGI 837 Query 1012 AYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 YLH +HRDL N+LLD D ++ DFG+AK + + Sbjct 838 CYLHHDCDPVIVHRDLKPSNILLDADFEARVADFGVAKLIQTDES----MSVVAGSYGYI 893 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM-TVLRLTEL 1127 APE + SD++S+GV L E++T S + + ++ + ++ T + E+ Sbjct 894 APEYAYTLQVDKKSDIYSYGVILLEIITGKRSVEPEFGEGNSIVDWVRSKLKTKEDVEEV 953 Query 1128 LER--GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 L++ G + ++ + C + RP +++ IL+ K + +V Sbjct 954 LDKSMGRSCSLIREEMKQMLRIALLCTSRSPTDRPPMRDVLLILQEAKPKRKTVGDNVIV 1013 Query 1186 V 1186 V Sbjct 1014 V 1014 Score = 189 bits (479), Expect = 2e-47, Method: Composition-based stats. Identities = 73/395 (18%), Positives = 120/395 (30%), Gaps = 60/395 (15%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQ-LSFHRVDQKEI--TQLSHLGQGTRTNVY 604 RC G + G P L Q L+F D E + LG G+ VY Sbjct 675 TRCFQKSYGNRVDGGGRNGGDIGPWKLTAFQRLNFTADDVVECLSKTDNILGMGSTGTVY 734 Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664 + +G+ K G+ R ++ V ++ Sbjct 735 KA---EMPNGEIIAVKKLWGKNKENGKIRRRKSGV----------------LAEVDVLGN 775 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP----MAWKMVVAQQLAS 720 V H ++ + G C +++ EY+ +G LD L + +A +A Sbjct 776 VRHRNIVRLLGCCTNRDCTMLLYEYMPNGSLDDLLHGGDKTMTAAAEWTALYQIAIGVAQ 835 Query 721 ALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER---VE 774 + YL + +VH ++ NILL +++D GV + E Sbjct 836 GICYLHHDCDPVIVHRDLKPSNILLD-------ADFEARVADFGVAKLIQTDESMSVVAG 888 Query 775 RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA--PLQSRSPS----------- 821 ++APE + D + +G LLEI + P S Sbjct 889 SYGYIAPEYA--YTLQVDKKSDIYSYGVILLEIITGKRSVEPEFGEGNSIVDWVRSKLKT 946 Query 822 --EKEHF----YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + E R L Q+ + C + PT RP R +L L +P Sbjct 947 KEDVEEVLDKSMGRSCSLIREEMKQMLRIALLCTSRSPTDRPPMRDVLLILQEAKPKRKT 1006 Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910 V +D + D+ G Sbjct 1007 VGDNVIVVGDVNDVNFEDVCSVDVGHDVKCQRIGV 1041 >sp|Q9C660|PEK10_ARATH Proline-rich receptor-like protein kinase PERK10 OS=Arabidopsis thaliana OX=3702 GN=PERK10 PE=1 SV=2 Length=762 Score = 231 bits (590), Expect = 2e-62, Method: Composition-based stats. Identities = 84/391 (21%), Positives = 146/391 (37%), Gaps = 29/391 (7%) Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS---CPQLATLTSQCLTYEPTQ 855 G L+ + G + ++ + +P P P+ + + + P Sbjct 334 SIGVALVLLTLIGVVVCCLKKRKKRLSTIGGGYVMPTPMESSSPRSDSALLKTQSSAPLV 393 Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYC 915 + + + + + V LGEG FG+V Sbjct 394 GNRSS-----NRTYLSQSEPGGFGQSRELFSYEELVIATNGFSDENLLGEGGFGRVYKGV 448 Query 916 YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 +VAVK LK G R +K E+D + ++H +++ G C + + Sbjct 449 L-----PDERVVAVKQLKIGGGQGDRE-FKAEVDTISRVHHRNLLSMVGYCISENRR--L 500 Query 976 LVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNV 1029 L+ +YVP +L +L + A + A G+AYLH IHRD+ + N+ Sbjct 501 LIYDYVPNNNLYFHLHAAGTPGLDWATRVKIAAGAARGLAYLHEDCHPRIIHRDIKSSNI 560 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 LL+N+ + DFGLAK + + + R + APE K SDV+SFGV Sbjct 561 LLENNFHALVSDFGLAKLALDCNTHITTR--VMGTFGYMAPEYASSGKLTEKSDVFSFGV 618 Query 1090 TLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP-CEVYHL 1147 L EL+T S P L+ A+ ++ TE E++ + Sbjct 619 VLLELITGRKPVDASQPLGDESLVEWARPLLSNATETEEFTALADPKLGRNYVGVEMFRM 678 Query 1148 MK---NCWETEASFRPTFENLIPILKTVHEK 1175 ++ C A+ RP ++ ++ E+ Sbjct 679 IEAAAACIRHSATKRPRMSQIVRAFDSLAEE 709 Score = 219 bits (559), Expect = 2e-58, Method: Composition-based stats. Identities = 64/346 (18%), Positives = 113/346 (33%), Gaps = 59/346 (17%) Query 499 SLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGET 558 L+ RK + G +V+ ++ R+ + + Sbjct 351 CLKKRKKRLSTIGGGYVMP-------------TPMESSSPRSDSALLKTQSSAPLVGNRS 397 Query 559 SNLIIMRGARASPRTLNLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616 SN + + + S+ + + + LG+G VY+G L Sbjct 398 SNRTYLSQSEPGGFGQSRELFSYEELVIATNGFSDENLLGEGGFGRVYKGVL-------- 449 Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676 E V +K L F +S+V H +L + G Sbjct 450 -----------------PDERVVAVKQLKIGGGQGDREFKAEVDTISRVHHRNLLSMVGY 492 Query 677 CVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENK---NLVH 732 C+ +++ +YV + L L + A ++ +A A L+YL ++H Sbjct 493 CISENRRLLIYDYVPNNNLYFHLHAAGTPGLDWATRVKIAAGAARGLAYLHEDCHPRIIH 552 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGG 787 ++ NILL A +SD G+ AL + ++APE G Sbjct 553 RDIKSSNILLENNFHAL-------VSDFGLAKLALDCNTHITTRVMGTFGYMAPEYASSG 605 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833 L+ D + FG LLE+ G P+ + P E + L Sbjct 606 --KLTEKSDVFSFGVVLLELI-TGRKPVDASQPLGDESLVEWARPL 648 >sp|O88506|STK39_RAT STE20/SPS1-related proline-alanine-rich protein kinase OS=Rattus norvegicus OX=10116 GN=Stk39 PE=1 SV=2 Length=553 Score = 227 bits (578), Expect = 2e-62, Method: Composition-based stats. Identities = 71/290 (24%), Positives = 118/290 (41%), Gaps = 24/290 (8%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + + +G G V P E VA+K + + +EI Sbjct 65 WPICRDAYELQEVIGSGATAVVQAALCKPRQ----ERVAIKRINLEKCQTSMDELLKEIQ 120 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---------RHSIGLAQL 1000 + H +++ Y + E L LVM+ + GS+ D + + A + Sbjct 121 AMSQCSHPNVVTYYTSFVVKDE--LWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAII 178 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--VR 1058 +++ EG+ YLH IHRDL A N+LL D V+I DFG++ + G + R VR Sbjct 179 ATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVR 238 Query 1059 EDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 + W APE +++ + + +D+WSFG+T EL T P + ++ + Sbjct 239 KTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTL--- 295 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 Q L +E E + K L+ C + + S RPT L+ Sbjct 296 QNDPPTLETGVEDKEMM---KKYGKSFRKLLSLCLQKDPSKRPTAAELLK 342 Score = 173 bits (438), Expect = 2e-44, Method: Composition-based stats. Identities = 50/264 (19%), Positives = 97/264 (37%), Gaps = 37/264 (14%) Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 + ++ RV +K ++ ++ + MSQ SH ++ + V E +V + + Sbjct 92 KPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLS 151 Query 692 HGPLDVWLR-------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 G + ++ + G + A + +++ L YL +H ++ NILL Sbjct 152 GGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGE 211 Query 745 LGLAEGTSPFIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAM 795 G ++++D GV + R+ V W+APE + Sbjct 212 DG-------SVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKA 263 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-----------HRLPEPSCPQLATL 844 D W FG T +E+ G AP P + + + + L Sbjct 264 DMWSFGITAIELA-TGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKL 322 Query 845 TSQCLTYEPTQRPSFRTILRDLTR 868 S CL +P++RP+ +L+ Sbjct 323 LSLCLQKDPSKRPTAAELLKCKFF 346 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 Length=788 Score = 232 bits (592), Expect = 2e-62, Method: Composition-based stats. Identities = 84/326 (26%), Positives = 129/326 (40%), Gaps = 29/326 (9%) Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 S T PT + + +S S H + ++ +G Sbjct 1 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIG 60 Query 905 EGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963 +G+F KV L + TG+ VAVK + K +E+ I++ L H +I+K Sbjct 61 KGNFAKVKL----ARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLF 116 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHR 1022 E EK+L LVMEY G + DYL H + + +QI + Y H + +HR Sbjct 117 EVIE--TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHR 174 Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YA 1081 DL A N+LLD D +KI DFG + G++ + + APE + K+ Sbjct 175 DLKAENLLLDADMNIKIADFGFSNEFTFGNKL----DTFCGSPPYAAPELFQGKKYDGPE 230 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 DVWS GV LY L++ + L E + RG + P Sbjct 231 VDVWSLGVILYTLVSGSLPFD---------------GQNLKELRERVLRG-KYRIPFYMS 274 Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167 + +L+K S R T E ++ Sbjct 275 TDCENLLKKFLILNPSKRGTLEQIMK 300 Score = 192 bits (488), Expect = 2e-49, Method: Composition-based stats. Identities = 61/355 (17%), Positives = 113/355 (32%), Gaps = 49/355 (14%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 +P SN+I R + S + + L +G+G V R + G Sbjct 27 KPSSKSNMIRGRNSATS---------ADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGK 77 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLA 671 V +K++D + + + + +M ++H ++ Sbjct 78 ------------------------EVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIV 113 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 + V +V EY G + +L G + +Q+ SA+ Y K +V Sbjct 114 KLFEVIETEKTLYLVMEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYCHQKFIV 172 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGA 788 H ++ N+LL IK++D G + P+ APE G Sbjct 173 HRDLKAENLLLD-------ADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKK 225 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQ 847 +D W G L + G P ++ E R +R+P L + Sbjct 226 YD-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 283 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902 L P++R + I++D H ++ P + + Sbjct 284 FLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYT 338 >sp|O49445|LRK72_ARATH Probable L-type lectin-domain containing receptor kinase VII.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK72 PE=3 SV=2 Length=681 Score = 230 bits (586), Expect = 2e-62, Method: Composition-based stats. Identities = 74/322 (23%), Positives = 123/322 (38%), Gaps = 18/322 (6%) Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917 F + R RL+ P + + +G G KV + Sbjct 310 CFYVVRRRRQRLEGDVEDWETEYWPHRVQYKDVLEATKGFSDENMIGYGGNSKVYRGVLE 369 Query 918 PTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 G+ VAVK + S + E+ L L H++I+ KG +G +SL Sbjct 370 ------GKEVAVKRIMMSPRESVGATSEFLAEVSSLGRLRHKNIVGLKG-WSKKGGESLI 422 Query 976 LVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVL 1030 L+ EY+ GS+ + + + + + + GM YLH +HRD+ + NVL Sbjct 423 LIYEYMENGSVDKRIFDCNEMLNWEERMRVIRDLASGMLYLHEGWETKVLHRDIKSSNVL 482 Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 LD D ++GDFGLAK E + APE +K + +DV+SFGV Sbjct 483 LDKDMNARVGDFGLAKLQNTSKEMVST-THVVGTAGYMAPELVKTGRASAQTDVYSFGVF 541 Query 1091 LYELLTHCDSSQSPPTKFLELI-GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149 + E++ + +E I G+ + V L E ++ + + Sbjct 542 VLEVVCGRRPIEEGREGIVEWIWGLMEKDKVVDGLDERIKANGVFVVEE--VEMALRIGL 599 Query 1150 NCWETEASFRPTFENLIPILKT 1171 C + RP ++ IL+ Sbjct 600 LCVHPDPRVRPKMRQVVQILEQ 621 Score = 185 bits (470), Expect = 1e-47, Method: Composition-based stats. Identities = 57/305 (19%), Positives = 111/305 (36%), Gaps = 61/305 (20%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 K + + +G G + VY G L G+E+ V ++ Sbjct 345 ATKGFSDENMIGYGGNSKVYRGVLE------------------------GKEVAVKRIMM 380 Query 645 DPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPE-NIMVTEYVEHGPLDVWLRRE 702 P A F S + ++ H ++ + G +G E I++ EY+E+G +D + Sbjct 381 SPRESVGATSEFLAEVSSLGRLRHKNIVGLKGWSKKGGESLILIYEYMENGSVDKRIFDC 440 Query 703 RGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + +M V + LAS + YL ++H ++ N+LL + ++ D Sbjct 441 NEMLNWEERMRVIRDLASGMLYLHEGWETKVLHRDIKSSNVLLDK-------DMNARVGD 493 Query 760 PGVG------LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ +S V ++APE + G S D + FG +LE+ G Sbjct 494 FGLAKLQNTSKEMVSTTHVVGTAGYMAPELVKTGRA--SAQTDVYSFGVFVLEVVC-GRR 550 Query 814 PLQSRSPSEKEHFY--QRQHRLPEPSCPQLA--------------TLTSQCLTYEPTQRP 857 P++ E + + ++ + ++ + C+ +P RP Sbjct 551 PIEEGREGIVEWIWGLMEKDKVVDGLDERIKANGVFVVEEVEMALRIGLLCVHPDPRVRP 610 Query 858 SFRTI 862 R + Sbjct 611 KMRQV 615 >sp|Q8VHF0|MARK3_RAT MAP/microtubule affinity-regulating kinase 3 OS=Rattus norvegicus OX=10116 GN=Mark3 PE=1 SV=1 Length=797 Score = 232 bits (592), Expect = 2e-62, Method: Composition-based stats. Identities = 76/280 (27%), Positives = 118/280 (42%), Gaps = 29/280 (10%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEID 949 H + ++ +G+G+F KV L + TG VA+K + K P +E+ Sbjct 50 QPHIGNYRLLKTIGKGNFAKVKL----ARHILTGREVAIKIIDKTQLNPTSLQKLFREVR 105 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQIC 1008 I++ L H +I+K E EK+L L+MEY G + DYL H + + +QI Sbjct 106 IMKILNHPNIVKLFEVIE--TEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIV 163 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 + Y H + +HRDL A N+LLD D +KI DFG + G + + + Sbjct 164 SAVQYCHQKRIVHRDLKAENLLLDADMNIKITDFGFSNEFTVGSKL----DTFCGSPPYA 219 Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + K+ DVWS GV LY L++ + L E Sbjct 220 APELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFD---------------GQNLKELRER 264 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + RG + P + +L+K R T E ++ Sbjct 265 VLRG-KYRIPFYMSTDCENLLKRFLVLNPVKRGTLEQIMK 303 Score = 189 bits (481), Expect = 2e-48, Method: Composition-based stats. Identities = 57/319 (18%), Positives = 106/319 (33%), Gaps = 41/319 (13%) Query 556 GETSNLIIMRGARASPRTLN-LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 G+ + R R+ R N ++ + + L +G+G V R + G Sbjct 22 GDGRQEVTSRTGRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGR- 80 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAF 672 V +K++D + + + +M ++H ++ Sbjct 81 -----------------------EVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 117 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVH 732 + V ++ EY G + +L G + +Q+ SA+ Y K +VH Sbjct 118 LFEVIETEKTLYLIMEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYCHQKRIVH 176 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGAN 789 ++ N+LL IK++D G + P+ APE G Sbjct 177 RDLKAENLLLD-------ADMNIKITDFGFSNEFTVGSKLDTFCGSPPYAAPELFQGKKY 229 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQC 848 +D W G L + G P ++ E R +R+P L + Sbjct 230 D-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRF 287 Query 849 LTYEPTQRPSFRTILRDLT 867 L P +R + I++D Sbjct 288 LVLNPVKRGTLEQIMKDRW 306 >sp|Q9Z138|ROR2_MOUSE Tyrosine-protein kinase transmembrane receptor ROR2 OS=Mus musculus OX=10090 GN=Ror2 PE=1 SV=2 Length=944 Score = 234 bits (598), Expect = 2e-62, Method: Composition-based stats. Identities = 90/410 (22%), Positives = 152/410 (37%), Gaps = 55/410 (13%) Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCP 839 P C N D P R S+ Y + Sbjct 375 PWCFTQNKNVRVELCDV---------------PPCSPRDGSKMGILYILVPSIAIPLVIA 419 Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899 L L C + + + + + + + + ++ Sbjct 420 CLFFLVCMCRNKQKASASTP----QRRQLMASPSQDMEMPLISQHKQAKLKEISLSTVRF 475 Query 900 IRDLGEGHFGKVSLYCYDPTNDGTG-EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 + +LGE FGKV G + VA+K LK R ++QE + L H + Sbjct 476 MEELGEDRFGKVYKGHLFGPAPGEPTQAVAIKTLKDKAEGPLREEFRQEAMLRARLQHPN 535 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----------------RHSIGLAQLL 1001 I+ G ++ L ++ Y G L ++L + ++ + Sbjct 536 IVCLLGVVTK--DQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFV 593 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 QI GM +L + H +H+DLA RNVL+ + V+I D GL + V +YY++ + Sbjct 594 HVVAQIAAGMEFLSSHHVVHKDLATRNVLVYDKLNVRISDLGLFREVY-SADYYKLMGNS 652 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 P+ W +PE + KF SD+WS+GV L+E+ ++ + Sbjct 653 LLPIRWMSPEAVMYGKFSIDSDIWSYGVVLWEVFSYGLQ--------------PYCGYSN 698 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + E++ + LP PD CP VY LM CW S RP F+++ L++ Sbjct 699 QDVVEMIRSRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRS 748 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 82/435 (19%), Positives = 151/435 (35%), Gaps = 77/435 (18%) Query 475 WSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQ 534 W+ HP+ L+ + + G R P Q +G + + ++ Sbjct 340 WALQHPHSHRLSSTEFPELGGGHAYCR---NPGGQVEGPWCFTQNKNVRVELCDVPPCSP 396 Query 535 GCLLRAGDD--------------CFSLRRC-CLPQPGETSNLIIMRGARASPRT------ 573 + G C C C + +++ R ASP Sbjct 397 RDGSKMGILYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPL 456 Query 574 -LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 Q + + + LG+ VY+G L G+P + Sbjct 457 ISQHKQAKLKEISLSTVRFMEELGEDRFGKVYKGHLFGPAPGEPTQ-------------- 502 Query 633 RGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 V +K L D + + F + A L +++ H ++ + GV + M+ Y Sbjct 503 -----AVAIKTLKDKAEGPLREEFRQEAMLRARLQHPNIVCLLGVVTKDQPLSMIFSYCS 557 Query 692 HGPLDVWL---------------RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVC 736 HG L +L R + + + V Q+A+ + +L + ++VH ++ Sbjct 558 HGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHVVAQIAAGMEFLSSHHVVHKDLA 617 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANS 790 RN+L+ +++SD G+ S + + I W++PE + G S Sbjct 618 TRNVLV-------YDKLNVRISDLGLFREVYSADYYKLMGNSLLPIRWMSPEAVMYGKFS 670 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-SCPQ-LATLTSQC 848 + D W +G L E+ G P S + + + LP P CP + L +C Sbjct 671 ID--SDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRSRQVLPCPDDCPAWVYALMIEC 728 Query 849 LTYEPTQRPSFRTIL 863 P++RP F+ I Sbjct 729 WNEFPSRRPRFKDIH 743 >sp|Q9Z1W9|STK39_MOUSE STE20/SPS1-related proline-alanine-rich protein kinase OS=Mus musculus OX=10090 GN=Stk39 PE=1 SV=1 Length=556 Score = 227 bits (578), Expect = 2e-62, Method: Composition-based stats. Identities = 71/290 (24%), Positives = 118/290 (41%), Gaps = 24/290 (8%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + + +G G V P E VA+K + + +EI Sbjct 68 WPICRDAYELQEVIGSGATAVVQAALCKPRQ----ERVAIKRINLEKCQTSMDELLKEIQ 123 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---------RHSIGLAQL 1000 + H +++ Y + E L LVM+ + GS+ D + + A + Sbjct 124 AMSQCSHPNVVTYYTSFVVKDE--LWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAII 181 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--VR 1058 +++ EG+ YLH IHRDL A N+LL D V+I DFG++ + G + R VR Sbjct 182 ATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVR 241 Query 1059 EDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 + W APE +++ + + +D+WSFG+T EL T P + ++ + Sbjct 242 KTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTL--- 298 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 Q L +E E + K L+ C + + S RPT L+ Sbjct 299 QNDPPTLETGVEDKEMM---KKYGKSFRKLLSLCLQKDPSKRPTAAELLK 345 Score = 173 bits (438), Expect = 3e-44, Method: Composition-based stats. Identities = 50/264 (19%), Positives = 97/264 (37%), Gaps = 37/264 (14%) Query 633 RGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 + ++ RV +K ++ ++ + MSQ SH ++ + V E +V + + Sbjct 95 KPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLS 154 Query 692 HGPLDVWLR-------RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 G + ++ + G + A + +++ L YL +H ++ NILL Sbjct 155 GGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGE 214 Query 745 LGLAEGTSPFIKLSDPGVGLGALS---------REERVERIPWLAPECLPGGANSLSTAM 795 G ++++D GV + R+ V W+APE + Sbjct 215 DG-------SVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQ-VRGYDFKA 266 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-----------HRLPEPSCPQLATL 844 D W FG T +E+ G AP P + + + + L Sbjct 267 DMWSFGITAIELA-TGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKL 325 Query 845 TSQCLTYEPTQRPSFRTILRDLTR 868 S CL +P++RP+ +L+ Sbjct 326 LSLCLQKDPSKRPTAAELLKCKFF 349 >sp|Q9T020|Y4391_ARATH Probable receptor-like protein kinase At4g39110 OS=Arabidopsis thaliana OX=3702 GN=At4g39110 PE=3 SV=1 Length=878 Score = 233 bits (595), Expect = 2e-62, Method: Composition-based stats. Identities = 74/275 (27%), Positives = 115/275 (42%), Gaps = 17/275 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + D G VAVK Q + ++ EI +L L H H++ Sbjct 532 IGVGGFGNVYIGTLD-----DGTKVAVKRGNP-QSEQGITEFQTEIQMLSKLRHRHLVSL 585 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHA--- 1016 G C++ E + LV E++ G RD+L + Q L G+ YLH Sbjct 586 IGYCDENSE--MILVYEFMSNGPFRDHLYGKNLAPLTWKQRLEICIGSARGLHYLHTGTA 643 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 Q IHRD+ + N+LLD + K+ DFGL+K V G + V + PE + Sbjct 644 QGIIHRDVKSTNILLDEALVAKVADFGLSKDVAFGQNH--VSTAVKGSFGYLDPEYFRRQ 701 Query 1077 KFYYASDVWSFGVTLYE-LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + SDV+SFGV L E L + P + + L A L ++++ Sbjct 702 QLTDKSDVYSFGVVLLEALCARPAINPQLPREQVNLAEWAMQWKRKGLLEKIIDPHLAGT 761 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + + + C E RPT +++ L+ Sbjct 762 INPESMKKFAEAAEKCLEDYGVDRPTMGDVLWNLE 796 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 65/319 (20%), Positives = 108/319 (34%), Gaps = 60/319 (19%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 LS + K +G G NVY G L Sbjct 513 YFSLSELQEATKNFEASQIIGVGGFGNVYIGTLDDG------------------------ 548 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 +V +K +P F ++S++ H HL + G C E I+V E++ +GP Sbjct 549 -TKVAVKRGNPQSEQGITEFQTEIQMLSKLRHRHLVSLIGYCDENSEMILVYEFMSNGPF 607 Query 696 DVWLRRER-GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGT 751 L + + ++ + A L YL + ++H +V NILL +A Sbjct 608 RDHLYGKNLAPLTWKQRLEICIGSARGLHYLHTGTAQGIIHRDVKSTNILLDEALVA--- 664 Query 752 SPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 K++D G+ + V +L PE L+ D + FG LLE Sbjct 665 ----KVADFGLSKDVAFGQNHVSTAVKGSFGYLDPEYFR--RQQLTDKSDVYSFGVVLLE 718 Query 807 ICFDG-----EAPLQSRSPSEKEHFYQRQHRLPEPSCPQL------------ATLTSQCL 849 + P + + +E ++R+ L + P L A +CL Sbjct 719 ALCARPAINPQLPREQVNLAEWAMQWKRKGLLEKIIDPHLAGTINPESMKKFAEAAEKCL 778 Query 850 TYEPTQRPSFRTILRDLTR 868 RP+ +L +L Sbjct 779 EDYGVDRPTMGDVLWNLEY 797 >sp|Q10LQ2|CIPKA_ORYSJ CBL-interacting protein kinase 10 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK10 PE=2 SV=1 Length=451 Score = 223 bits (569), Expect = 2e-62, Method: Composition-based stats. Identities = 58/268 (22%), Positives = 111/268 (41%), Gaps = 26/268 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHII 960 LG+G F KV Y N + VA+K + + + ++EI ++ + H I+ Sbjct 19 LGQGSFAKV----YHGRNIKNSQSVAIKVIDKEKILKCELMDQIRREISVMNLVRHPCIV 74 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + + + + ++EYV G L + + R + + QQ+ + + H++ Sbjct 75 QLYEVMATKTK--IYFILEYVKGGELFNKVRRGRLKEEVARKYFQQLISAIDFCHSRGVY 132 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 HRDL N+LLD +R +KI DFGL+ + + +P + APE + + Sbjct 133 HRDLKPENLLLDENRNLKISDFGLSALAECKRQDGLLHTTCGTPA-YVAPEVINRKGYDG 191 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +DVW+ GV LY LL Q V+ + + + + E P Sbjct 192 AKADVWACGVILYVLLAGYLPFQD---------------KNVINMYKKICKAE-FKWPSW 235 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 ++ L++ + + R + ++ Sbjct 236 FSSDIRKLLRRILDPNPATRISVSEIME 263 Score = 184 bits (466), Expect = 9e-49, Method: Composition-based stats. Identities = 57/295 (19%), Positives = 98/295 (33%), Gaps = 45/295 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + K LGQG+ VY GR V +KV Sbjct 8 ILMKRYEIGKLLGQGSFAKVYHGRNIKNSQS------------------------VAIKV 43 Query 644 LDPSHH---DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 +D ++ S+M+ V H + ++ V + + EYV+ G L + Sbjct 44 IDKEKILKCELMDQIRREISVMNLVRHPCIVQLYEVMATKTKIYFILEYVKGGELFN--K 101 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 RG + QQL SA+ + ++ + H ++ N+LL + +K+SD Sbjct 102 VRRGRLKEEVARKYFQQLISAIDFCHSRGVYHRDLKPENLLLDE-------NRNLKISDF 154 Query 761 GVGLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ A + ++APE + D W G L + G P Sbjct 155 GLSALAECKRQDGLLHTTCGTPAYVAPEVINRKGYD-GAKADVWACGVILY-VLLAGYLP 212 Query 815 LQSRSPSEKE-HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 Q ++ + + + P + L + L P R S I+ D Sbjct 213 FQDKNVINMYKKICKAEFKWPSWFSSDIRKLLRRILDPNPATRISVSEIMEDPWF 267 >sp|Q61084|M3K3_MOUSE Mitogen-activated protein kinase kinase kinase 3 OS=Mus musculus OX=10090 GN=Map3k3 PE=1 SV=1 Length=626 Score = 228 bits (582), Expect = 2e-62, Method: Composition-based stats. Identities = 78/279 (28%), Positives = 130/279 (47%), Gaps = 24/279 (9%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP----QHRSGWKQEID 949 ++ + LG+G FG+V L + TG +A K ++ D + S + EI Sbjct 359 PINWRRGKLLGQGAFGRVYLCY----DVDTGRELASKQVQFDPDSPETSKEVSALECEIQ 414 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQIC 1008 +L+ L HE I++Y GC D+ EK L + MEY+P GS++D L + + + + +QI Sbjct 415 LLKNLQHERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQIL 474 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 EGM+YLH+ +HRD+ N+L D+ VK+GDFG +K + +W Sbjct 475 EGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGIRSVTGTPYWM 534 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 +PE + + +DVWS G T+ E+LT + PP E + + ++ Sbjct 535 SPEVISGEGYGRKADVWSLGCTVVEMLT-----EKPPWAEYEAMA---------AIFKIA 580 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + P ++ + EA RP+ E L+ Sbjct 581 TQPTNPQLPSHISEHGRDFLRRIF-VEARQRPSAEELLT 618 Score = 174 bits (440), Expect = 5e-44, Method: Composition-based stats. Identities = 62/373 (17%), Positives = 115/373 (31%), Gaps = 68/373 (18%) Query 478 SHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCL 537 ++P R ++V + R+R+ Q F L RS + G Sbjct 274 TYPRRYHVSVHHKDYNDGRRTFPRIRR----HQGNLFTLVPSSRSLST--------NGEN 321 Query 538 LRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQ 597 + R + ++ N + ++ ++ + + LGQ Sbjct 322 MGVAVQYLDPRGRL--RSADSENALTVQERNVPTKSPSAPI---------NWRRGKLLGQ 370 Query 598 GTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE 657 G VY L D G+EL DP + + Sbjct 371 GAFGRVY----------------------LCYDVDTGRELASKQVQFDPDSPETSKEVSA 408 Query 658 ---TASLMSQVSHTHLAFVHGVCVRGPENI--MVTEYVEHGPLDVWLRRERGHVPMAWKM 712 L+ + H + +G E I + EY+ G + L+ G + + Sbjct 409 LECEIQLLKNLQHERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKA-YGALTESVTR 467 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-------VGLG 765 +Q+ +SYL + +VH ++ G NIL ++ +KL D G + + Sbjct 468 KYTRQILEGMSYLHSNMIVHRDIKGANIL-------RDSAGNVKLGDFGASKRLQTICMS 520 Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 W++PE + G D W G T++E+ + + P Sbjct 521 GTGIRSVTGTPYWMSPEVISG--EGYGRKADVWSLGCTVVEMLTE-KPPWAEYEAMAAIF 577 Query 826 FYQRQHRLPEPSC 838 Q P+ Sbjct 578 KIATQPTNPQLPS 590 >sp|Q6P3Q4|STK4_XENTR Serine/threonine-protein kinase 4 OS=Xenopus tropicalis OX=8364 GN=stk4 PE=2 SV=1 Length=485 Score = 224 bits (572), Expect = 2e-62, Method: Composition-based stats. Identities = 63/270 (23%), Positives = 113/270 (42%), Gaps = 31/270 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V Y ++ T ++VA+K + + Q +EI I++ H++K Sbjct 35 KLGEGSYGSV----YKASHKETSQIVAIKQIPVESDLQ---EIIKEIAIMQQCDSLHVVK 87 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VME+ GS+ D L + ++ + Q +G+ YLH Sbjct 88 YYGSYFKNTD--LWIVMEFCGGGSISDIIRLRKQTLKEDETATILQSTLKGLEYLHFMRK 145 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+++ K+ DFG+A + + R FW APE ++E + Sbjct 146 IHRDIKAGNILLNSEGTAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 202 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP--RP 1137 +D+WS G+T E+ ++ +R ++ +P Sbjct 203 CVADIWSLGITAIEMAEGKPP---------------YAEIHPMRAIFMIPSNPPPTFRKP 247 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + + C R + L+ Sbjct 248 ELWSKDFVDFINLCLVKNPELRSSATELLQ 277 Score = 196 bits (497), Expect = 1e-52, Method: Composition-based stats. Identities = 57/300 (19%), Positives = 98/300 (33%), Gaps = 44/300 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 LS+ S ++ ++ L LG+G+ +VY+ + Sbjct 17 LSEESLNKQPEEVFDVLEKLGEGSYGSVYKASHKE------------------------T 52 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K + + ++M Q H+ +G + + +V E+ G + Sbjct 53 SQIVAIKQIPVESD--LQEIIKEIAIMQQCDSLHVVKYYGSYFKNTDLWIVMEFCGGGSI 110 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + + Q L YL +H ++ NILL G A Sbjct 111 SDIIRLRKQTLKEDETATILQSTLKGLEYLHFMRKIHRDIKAGNILLNSEGTA------- 163 Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D GV R + W+APE + + D W G T +E+ +G Sbjct 164 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITAIEMA-EG 220 Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P P R PE + CL P R S +L+ Sbjct 221 KPPYAEIHPMRAIFMIPSNPPPTFRKPELWSKDFVDFINLCLVKNPELRSSATELLQHPF 280 >sp|Q55CA6|Y0146_DICDI Probable serine/threonine-protein kinase DDB_G0270146 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0270146 PE=3 SV=1 Length=635 Score = 229 bits (583), Expect = 2e-62, Method: Composition-based stats. Identities = 75/320 (23%), Positives = 132/320 (41%), Gaps = 26/320 (8%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 TY + FR+ + P + ++ +G+G F Sbjct 30 TYNKSDTVDFRSKVIPQQSNLPPINNKTDRSHFRESMVASKKTIGAFVISDIAIGKGAFA 89 Query 910 KVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968 V + N +G+ VA+K K+ + S E DIL+ L HE+I++ G + Sbjct 90 TV----FKGLNTLSGDFVAIKRFEKSKISNEQHSSVSTEFDILQRLNHENIVRILG--RE 143 Query 969 QGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027 + E + + +EY+ GSL L + + + + + + +G+ YLH + IHRD+ A Sbjct 144 ENENYIYIFLEYMENGSLSTILNNFGTFPESLICNYVENVLKGLVYLHQEGVIHRDIKAA 203 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 N+L++ K+ DFG A + + + R +W APE ++ SD+WS Sbjct 204 NILINKAGEAKLSDFGTAGEIIKESD---KRYSVVGTPYWMAPEVIEISGHCQVSDIWSL 260 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 G T+ EL T PP L +G + + +R P PD E+ + Sbjct 261 GCTIIELFT-----SYPPYFDLNPLGAMY----------RICQDDRPPLPDDISSELANF 305 Query 1148 MKNCWETEASFRPTFENLIP 1167 ++ C+ R T + L+ Sbjct 306 LERCFCKSTEERATAKELLS 325 Score = 190 bits (483), Expect = 2e-49, Method: Composition-based stats. Identities = 58/321 (18%), Positives = 111/321 (35%), Gaps = 43/321 (13%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIA 652 +G+G V++G + G V +K + S ++ Sbjct 83 IGKGAFATVFKGLNTLSGDF------------------------VAIKRFEKSKISNEQH 118 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 + ++ +++H ++ + G + EY+E+G L L G P + Sbjct 119 SSVSTEFDILQRLNHENIVRILGREENENYIYIFLEYMENGSLSTIL-NNFGTFPESLIC 177 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGALS 768 + + L YL + ++H ++ NIL+ + G A KLSD G + Sbjct 178 NYVENVLKGLVYLHQEGVIHRDIKAANILINKAGEA-------KLSDFGTAGEIIKESDK 230 Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 R V W+APE + + D W G T++E+ F P +P + Sbjct 231 RYSVVGTPYWMAPEVIE--ISGHCQVSDIWSLGCTIIEL-FTSYPPYFDLNPLGAMYRIC 287 Query 829 RQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 + R LP+ +LA +C +R + + +L + N Sbjct 288 QDDRPPLPDDISSELANFLERCFCKSTEERATAKELLSHPWITKNRTNLINHQRNSSKQF 347 Query 887 SDPTVFHKRYLKKIRDLGEGH 907 + P + + K + G Sbjct 348 TSPQIIINNHQKSLLSNSSGG 368 >sp|Q8RWC9|CIPK1_ARATH CBL-interacting serine/threonine-protein kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CIPK1 PE=1 SV=2 Length=444 Score = 223 bits (568), Expect = 2e-62, Method: Composition-based stats. Identities = 72/264 (27%), Positives = 108/264 (41%), Gaps = 27/264 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHI 959 LGEG+FGKV + +G AVK + K+EI L+ L H HI Sbjct 25 TLGEGNFGKVKF----AKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLKHPHI 80 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ + + + +VME V G L D + + QQ+ +G++Y H++ Sbjct 81 VRLHEVLASKTK--INMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKG 138 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL NVLLD +KI DFGL+ + + SP + APE L + Sbjct 139 VFHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTCGSPN-YVAPEVLANRGY 197 Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 ASD+WS GV LY +LT C + L + + +G+ P P Sbjct 198 DGAASDIWSCGVILYVILTGCLPFDD---------------RNLAVLYQKICKGD-PPIP 241 Query 1138 DKCPCEVYHLMKNCWETEASFRPT 1161 ++K + R T Sbjct 242 RWLSPGARTMIKRMLDPNPVTRIT 265 Score = 169 bits (429), Expect = 5e-44, Method: Composition-based stats. Identities = 54/291 (19%), Positives = 90/291 (31%), Gaps = 44/291 (15%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + LG+G V +D +K++D S Sbjct 19 KYELGRTLGEGNFGKV------------------------KFAKDTVSGHSFAVKIIDKS 54 Query 648 ---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + +L + + H H+ +H V + MV E V G L + G Sbjct 55 RIADLNFSLQIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFDRI-VSNG 113 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763 + + QQL +SY +K + H ++ N+LL G IK++D G+ Sbjct 114 KLTETDGRKMFQQLIDGISYCHSKGVFHRDLKLENVLLDAKG-------HIKITDFGLSA 166 Query 764 -----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 ++APE L A D W G L + G P R Sbjct 167 LPQHFRDDGLLHTTCGSPNYVAPEVLANRGYD-GAASDIWSCGVILY-VILTGCLPFDDR 224 Query 819 SPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + + + + +P P T+ + L P R + I Sbjct 225 NLAVLYQKICKGDPPIPRWLSPGARTMIKRMLDPNPVTRITVVGIKASEWF 275 >sp|A2QHV0|SEPH_ASPNC Cytokinesis protein sepH OS=Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) OX=425011 GN=sepH PE=3 SV=1 Length=1336 Score = 237 bits (604), Expect = 2e-62, Method: Composition-based stats. Identities = 81/317 (26%), Positives = 125/317 (39%), Gaps = 28/317 (9%) Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVS 912 P++ P R D + +S V + + LG+G FG V Sbjct 15 PSKIPGTPAKTRLSRLNSSPAKQDKPKDDRVVKSSAKDVAELKDYQLGDCLGKGAFGSV- 73 Query 913 LYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 Y N TGE VAVK +K D EID+L+ L H +I+KY+G + Sbjct 74 ---YRALNWNTGETVAVKQIKLVDLPKSELRVIMLEIDLLKNLDHPNIVKYQGFV--KSA 128 Query 972 KSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030 ++L +++EY GSL + L+ Q+ G+ YLH Q IHRD+ N+L Sbjct 129 ETLNIILEYCENGSLHSIAKNFGRFPENLVGLYMSQVLHGLLYLHEQGVIHRDIKGANIL 188 Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 + LVK+ DFG+A +W APE ++ ASD+WS G T Sbjct 189 TTKEGLVKLADFGVA-----SRTTGLSESSVVGTPYWMAPEVIELSGATTASDIWSLGCT 243 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 + ELL + Q + R+ + P P V + Sbjct 244 VIELLEGKPPYYN-----------LQPMPALFRIV----NDDHPPLPQGASPAVKDFLMQ 288 Query 1151 CWETEASFRPTFENLIP 1167 C++ + + R + L+ Sbjct 289 CFQKDPNLRVSARKLLK 305 Score = 208 bits (530), Expect = 2e-53, Method: Composition-based stats. Identities = 68/328 (21%), Positives = 114/328 (35%), Gaps = 42/328 (13%) Query 550 CCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ-KEITQLSHLGQGTRTNVYEGRL 608 P S L + P+ + + S V + K+ LG+G +VY Sbjct 19 PGTPAKTRLSRLNSSPAKQDKPKDDRVVKSSAKDVAELKDYQLGDCLGKGAFGSVYRALN 78 Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH--HDIALAFYETASLMSQVS 666 G V +K + L+ + Sbjct 79 WNTGE------------------------TVAVKQIKLVDLPKSELRVIMLEIDLLKNLD 114 Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726 H ++ G ++ EY E+G L + + G P + Q+ L YL Sbjct 115 HPNIVKYQGFVKSAETLNIILEYCENGSLHS-IAKNFGRFPENLVGLYMSQVLHGLLYLH 173 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGALSREERVERIPWLAPECL 784 + ++H ++ G NIL + GL +KL+D GV LS V W+APE + Sbjct 174 EQGVIHRDIKGANILTTKEGL-------VKLADFGVASRTTGLSESSVVGTPYWMAPEVI 226 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH--FYQRQHRLPEPSCPQLA 842 + +TA D W G T++E+ +G+ P + P LP+ + P + Sbjct 227 E--LSGATTASDIWSLGCTVIELL-EGKPPYYNLQPMPALFRIVNDDHPPLPQGASPAVK 283 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 QC +P R S R +L+ + Sbjct 284 DFLMQCFQKDPNLRVSARKLLKHPWIVN 311 >sp|Q0CL79|SEPH_ASPTN Cytokinesis protein sepH OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=sepH PE=3 SV=2 Length=1342 Score = 237 bits (604), Expect = 2e-62, Method: Composition-based stats. Identities = 76/266 (29%), Positives = 116/266 (44%), Gaps = 29/266 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V Y N TGE VAVK +K P+ S + EID+L+ L H +I+KY Sbjct 67 LGKGAFGSV----YRALNWNTGETVAVKQIKLADLPK--SELRLEIDLLKNLDHPNIVKY 120 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 +G + ++L +++EY GSL + L+ Q+ G+ YLH Q IH Sbjct 121 QGFV--KSAETLNIILEYCENGSLHSIAKNFGRFPENLVGLYMSQVLHGLLYLHEQGVIH 178 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RD+ N+L + LVK+ DFG+A +W APE ++ A Sbjct 179 RDIKGANILTTKEGLVKLADFGVA-----SRTTGLSESSVVGTPYWMAPEVIELSGATTA 233 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 SD+WS G T+ ELL + Q + R+ + P P Sbjct 234 SDIWSLGCTVIELLEGKPPYYN-----------MQPMPALFRIV----NDDHPPLPQGAS 278 Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167 V + C++ + + R + L+ Sbjct 279 PAVKDFLMQCFQKDPNLRVSARKLLK 304 Score = 210 bits (534), Expect = 6e-54, Method: Composition-based stats. Identities = 62/288 (22%), Positives = 104/288 (36%), Gaps = 40/288 (14%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 K+ LG+G +VY G V +K + Sbjct 59 KDYQLGDCLGKGAFGSVYRALNWNTGE------------------------TVAVKQIKL 94 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 + L+ + H ++ G ++ EY E+G L + + G Sbjct 95 ADL-PKSELRLEIDLLKNLDHPNIVKYQGFVKSAETLNIILEYCENGSLHS-IAKNFGRF 152 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--L 764 P + Q+ L YL + ++H ++ G NIL + GL +KL+D GV Sbjct 153 PENLVGLYMSQVLHGLLYLHEQGVIHRDIKGANILTTKEGL-------VKLADFGVASRT 205 Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 LS V W+APE + + +TA D W G T++E+ +G+ P + P Sbjct 206 TGLSESSVVGTPYWMAPEVIE--LSGATTASDIWSLGCTVIELL-EGKPPYYNMQPMPAL 262 Query 825 H--FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 LP+ + P + QC +P R S R +L+ + Sbjct 263 FRIVNDDHPPLPQGASPAVKDFLMQCFQKDPNLRVSARKLLKHPWIVN 310 >sp|Q93Z30|BHP_ARATH Serine/threonine-protein kinase 12 OS=Arabidopsis thaliana OX=3702 GN=BHP PE=1 SV=1 Length=459 Score = 223 bits (569), Expect = 2e-62, Method: Composition-based stats. Identities = 66/321 (21%), Positives = 125/321 (39%), Gaps = 31/321 (10%) Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917 + I H +A + + + +++ +G + + + Sbjct 121 NIDVIKILEIHGAKHPMAPMHVKTAREVPEYEINPSELDFTQSKEITKGTY---CMAMWR 177 Query 918 PTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 G VAVK L + + E+ +L+ L H +I+++ G + Sbjct 178 ------GIQVAVKKLDDEVLSDDDQVRKFHDELALLQRLRHPNIVQFLGAVTQSN--PMM 229 Query 976 LVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLL 1031 +V EY+P G LR+ L R + A + +A I GM+YLH IHRDL N+L Sbjct 230 IVTEYLPRGDLRELLKRKGQLKPATAVRYALDIARGMSYLHEIKGDPIIHRDLEPSNILR 289 Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091 D+ +K+ DFG++K V + +D + APE ++ +DV+SF + + Sbjct 290 DDSGHLKVADFGVSKLVTVKEDKPFTCQDI--SCRYIAPEVFTSEEYDTKADVFSFALIV 347 Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 E++ + + ++ P + L++ C Sbjct 348 QEMIEGRMPFAEKEDSEASEAYAGKHRPLFKAPSK------------NYPHGLKTLIEEC 395 Query 1152 WETEASFRPTFENLIPILKTV 1172 W + + RPTF +I L+++ Sbjct 396 WHEKPAKRPTFREIIKRLESI 416 Score = 205 bits (521), Expect = 6e-56, Method: Composition-based stats. Identities = 83/399 (21%), Positives = 148/399 (37%), Gaps = 36/399 (9%) Query 526 VRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVD 585 ++EL + R DD +L + L++ R A P+ S + Sbjct 59 IKELIDSGIDANYRDIDDRTALHVAACQGLKDVVELLLDRKAEVDPKDRWGSTPFADAIF 118 Query 586 QKEITQLSHLG-QGTRT-----NVYEGRLRVEGSGDPEEGKMDDEDPLVPGR---DRGQE 636 K I + L G + +V R E +P E + G + Sbjct 119 YKNIDVIKILEIHGAKHPMAPMHVKTAREVPEYEINPSELDFTQSKEITKGTYCMAMWRG 178 Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 ++V +K LD S D F++ +L+ ++ H ++ G + ++VTEY+ G Sbjct 179 IQVAVKKLDDEVLSDDDQVRKFHDELALLQRLRHPNIVQFLGAVTQSNPMMIVTEYLPRG 238 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEG 750 L L+R +G + A + A +A +SYL ++H ++ NIL Sbjct 239 DLRELLKR-KGQLKPATAVRYALDIARGMSYLHEIKGDPIIHRDLEPSNIL-------RD 290 Query 751 TSPFIKLSDPGVGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLL 805 S +K++D GV +E++ ++APE + T D + F + Sbjct 291 DSGHLKVADFGVSKLVTVKEDKPFTCQDISCRYIAPEVFT--SEEYDTKADVFSFALIVQ 348 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHR-----LPEPSCPQLATLTSQCLTYEPTQRPSFR 860 E+ +G P + SE Y +HR + L TL +C +P +RP+FR Sbjct 349 EMI-EGRMPFAEKEDSEASEAYAGKHRPLFKAPSKNYPHGLKTLIEECWHEKPAKRPTFR 407 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899 I++ L + H K++ Sbjct 408 EIIKRLESILHHMGHKRQWRMRPLTCFQNFEHKKKHNWD 446 >sp|B0XR80|SAKA_ASPFC Mitogen-activated protein kinase sakA OS=Aspergillus fumigatus (strain CBS 144.89 / FGSC A1163 / CEA10) OX=451804 GN=sakA PE=3 SV=1 Length=366 Score = 220 bits (561), Expect = 2e-62, Method: Composition-based stats. Identities = 68/283 (24%), Positives = 109/283 (39%), Gaps = 29/283 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + TG+ VAVK + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SARDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L + ER P + E L++ + R + Sbjct 252 SLPKRERQPLANKFKNADPEAVDLLERMLVFDPKKRIRAGEAL 294 Score = 134 bits (336), Expect = 1e-32, Method: Composition-based stats. Identities = 36/231 (16%), Positives = 74/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + RD+ V +K ++ P ++ Y Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSARDQLTGQPVAVKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q4WSF6|HOG1_ASPFU Mitogen-activated protein kinase sakA OS=Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) OX=330879 GN=sakA PE=1 SV=1 Length=366 Score = 220 bits (561), Expect = 2e-62, Method: Composition-based stats. Identities = 68/283 (24%), Positives = 109/283 (39%), Gaps = 29/283 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + TG+ VAVK + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SARDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L + ER P + E L++ + R + Sbjct 252 SLPKRERQPLANKFKNADPEAVDLLERMLVFDPKKRIRAGEAL 294 Score = 134 bits (336), Expect = 1e-32, Method: Composition-based stats. Identities = 36/231 (16%), Positives = 74/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + RD+ V +K ++ P ++ Y Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSARDQLTGQPVAVKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q9LT96|Y5977_ARATH Probable leucine-rich repeat receptor-like protein kinase At5g49770 OS=Arabidopsis thaliana OX=3702 GN=At5g49770 PE=1 SV=1 Length=946 Score = 234 bits (597), Expect = 2e-62, Method: Composition-based stats. Identities = 75/261 (29%), Positives = 117/261 (45%), Gaps = 19/261 (7%) Query 923 TGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982 G+++A+K Q +K EI++L ++H++++K G C DQ E+ LV EY+P Sbjct 655 NGQVIAIKR-AQQGSMQGAFEFKTEIELLSRVHHKNVVKLLGFCFDQKEQ--MLVYEYIP 711 Query 983 LGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRL 1036 GSLRD L + + L A +G+AYLH IHRD+ + N+LLD Sbjct 712 NGSLRDGLSGKNGVKLDWTRRLKIALGSGKGLAYLHELADPPIIHRDVKSNNILLDEHLT 771 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 K+ DFGL+K V + + + V + + PE + SDV+ FGV + ELLT Sbjct 772 AKVADFGLSKLVGDPEKAH-VTTQVKGTMGYLDPEYYMTNQLTEKSDVYGFGVVMLELLT 830 Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE-----RGERLPRPDKCPCEVYHLMKNC 1151 E+ + L ELL+ L +K + C Sbjct 831 GKSPIDRGSYVVKEVKKKMDKSRNLYDLQELLDTTIIQNSGNLKGFEKY----VDVALQC 886 Query 1152 WETEASFRPTFENLIPILKTV 1172 E E RPT ++ L+++ Sbjct 887 VEPEGVNRPTMSEVVQELESI 907 Score = 197 bits (501), Expect = 2e-50, Method: Composition-based stats. Identities = 61/333 (18%), Positives = 116/333 (35%), Gaps = 40/333 (12%) Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 + RA T ++ + + E+ +G T +E + + Sbjct 587 QKKRAQRATDQMNPFAKWDAGKNEMDAPQLMGTKAFT--FEELSKCTNNFSDANDVGGGG 644 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 V + +K A F L+S+V H ++ + G C E + Sbjct 645 YGQVYKGTLPNGQVIAIKRAQQGSMQGAFEFKTEIELLSRVHHKNVVKLLGFCFDQKEQM 704 Query 685 MVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNI 740 +V EY+ +G L L + G + ++ +A L+YL ++H +V NI Sbjct 705 LVYEYIPNGSLRDGLSGKNGVKLDWTRRLKIALGSGKGLAYLHELADPPIIHRDVKSNNI 764 Query 741 LLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTA 794 LL K++D G+ A + + +L PE N L+ Sbjct 765 LLDE-------HLTAKVADFGLSKLVGDPEKAHVTTQVKGTMGYLDPEYYMT--NQLTEK 815 Query 795 MDKWGFGATLLEICFDGEAPLQSRS--PSEKEHFYQRQHRLPEPS--------------- 837 D +GFG +LE+ G++P+ S E + + L + Sbjct 816 SDVYGFGVVMLELL-TGKSPIDRGSYVVKEVKKKMDKSRNLYDLQELLDTTIIQNSGNLK 874 Query 838 -CPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + QC+ E RP+ ++++L + Sbjct 875 GFEKYVDVALQCVEPEGVNRPTMSEVVQELESI 907 >sp|Q8BRK8|AAPK2_MOUSE 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Mus musculus OX=10090 GN=Prkaa2 PE=1 SV=3 Length=552 Score = 226 bits (576), Expect = 2e-62, Method: Composition-based stats. Identities = 78/274 (28%), Positives = 106/274 (39%), Gaps = 30/274 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953 + LG G FGKV + + TG VAVK L K+EI L+ Sbjct 15 HYVLGDTLGVGTFGKVKIGEHQ----LTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012 H HIIK + +VMEYV G L DY+ +H + + QQI + Sbjct 71 FRHPHIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVD 128 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE Sbjct 129 YCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 184 Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + D+WS GV LY LL L RG Sbjct 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLF----------------KKIRG 228 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 PD V L+ + + + R T +++ Sbjct 229 GVFYIPDYLNRSVATLLMHMLQVDPLKRATIKDI 262 Score = 179 bits (455), Expect = 2e-46, Method: Composition-based stats. Identities = 57/298 (19%), Positives = 96/298 (32%), Gaps = 39/298 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 Q RV LG GT V G ++ G Sbjct 4 KQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGH----------------------- 40 Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +V +K+L+ D+ + H H+ ++ V + MV EYV G Sbjct 41 -KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGG 99 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L ++ + G V + QQ+ SA+ Y +VH ++ N+LL Sbjct 100 ELFDYICKH-GRVEEVEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLD-------AQM 151 Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ E + APE + G + +D W G L + Sbjct 152 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSCGVILYALLCG 210 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 P+ + +P+ +ATL L +P +R + + I Sbjct 211 TLPFDDEHVPTLFKKIRGGVFYIPDYLNRSVATLLMHMLQVDPLKRATIKDIREHEWF 268 >sp|G4N7X0|MST11_PYRO7 Mitogen-activated protein kinase kinae kinase MST11 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507 GN=MST11 PE=1 SV=1 Length=915 Score = 234 bits (596), Expect = 2e-62, Method: Composition-based stats. Identities = 81/299 (27%), Positives = 135/299 (45%), Gaps = 38/299 (13%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC----------GPQHR 941 + K +G+G FG V L + TGE++AVK ++A Sbjct 636 WDDSKWMKGALIGQGSFGCVYL----ALHAITGELLAVKQVEAPSPGANSQNDARKKSMI 691 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQL 1000 K+EI +LR L H +I++Y GC + L + +EYVP GS++ L + + + Sbjct 692 EALKREISLLRDLRHPNIVQYLGC--GSSAEYLNIFLEYVPGGSVQTMLNSYGALPEPLV 749 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP-----EGHEYY 1055 F +QI G++YLH + IHRD+ N+L+DN +KI DFG++K + G Sbjct 750 RSFVRQILNGLSYLHEREIIHRDIKGANILVDNKGTIKISDFGISKKIEATNLLNGANNN 809 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 + R VFW APE +K+ + +D+WS G + E++T T+ + I Sbjct 810 KHRPSLQGSVFWMAPEVVKQTSYTRKADIWSLGCLVVEMMTGTHPFPD-CTQLQAIFKIG 868 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTV 1172 G+ T P+ E + +E + + RP+ ++L+ P L + Sbjct 869 GGKAT-------------PTIPEDASTEAKAFLAQTFEMDHNKRPSADDLMLSPFLTPI 914 Score = 186 bits (473), Expect = 5e-47, Method: Composition-based stats. Identities = 60/302 (20%), Positives = 106/302 (35%), Gaps = 39/302 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S LS D + + + +GQG+ VY + G E + + PG + Sbjct 629 SFLSGESWDDSKWMKGALIGQGSFGCVYLALHAITG----ELLAVKQVEAPSPGANSQN- 683 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 D + A SL+ + H ++ G + EYV G + Sbjct 684 --------DARKKSMIEALKREISLLRDLRHPNIVQYLGCGSSAEYLNIFLEYVPGGSVQ 735 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 L G +P +Q+ + LSYL + ++H ++ G NIL+ G IK Sbjct 736 TML-NSYGALPEPLVRSFVRQILNGLSYLHEREIIHRDIKGANILVDNKG-------TIK 787 Query 757 LSDPGVGLGALS------------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 +SD G+ + R + W+APE + S + D W G + Sbjct 788 ISDFGISKKIEATNLLNGANNNKHRPSLQGSVFWMAPEVVKQ--TSYTRKADIWSLGCLV 845 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQH---RLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861 +E+ G P + + +PE + + +Q + +RPS Sbjct 846 VEMM-TGTHPFPDCTQLQAIFKIGGGKATPTIPEDASTEAKAFLAQTFEMDHNKRPSADD 904 Query 862 IL 863 ++ Sbjct 905 LM 906 >sp|Q9ZQQ7|Y2144_ARATH Putative leucine-rich repeat receptor-like serine/threonine-protein kinase At2g14440 OS=Arabidopsis thaliana OX=3702 GN=At2g14440 PE=3 SV=1 Length=886 Score = 233 bits (594), Expect = 2e-62, Method: Composition-based stats. Identities = 73/378 (19%), Positives = 143/378 (38%), Gaps = 25/378 (7%) Query 809 FDGEAPL--QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 G P Q R ++ + +H+ +A++ C+ I Sbjct 496 LRGSVPQALQDRENNDGLKLLRGKHQPKSWLVAIVASI--SCVA---VTIIVLVLIFIFR 550 Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926 R ++ + + + LG+G FG V E Sbjct 551 RRKSSTRKVIRPSLEMKNRRFKYSEVKEMTNNFEVVLGKGGFGVVYHGFL------NNEQ 604 Query 927 VAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 VAVK L ++ +K E+++L ++H +++ G C+ + L L+ E++ G+L Sbjct 605 VAVKVLSQSSTQGYKE-FKTEVELLLRVHHVNLVSLVGYCDKGND--LALIYEFMENGNL 661 Query 987 RDYLPRHS----IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKI 1039 +++L + L A + G+ YLH +HRD+ + N+LL K+ Sbjct 662 KEHLSGKRGGPVLNWPGRLKIAIESALGIEYLHIGCKPPMVHRDVKSTNILLGLRFEAKL 721 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD 1099 DFGL+++ G + + V + + + PE ++ SDV+SFG+ L E++T Sbjct 722 ADFGLSRSFLVGSQTH-VSTNVAGTLGYLDPEYYQKNWLTEKSDVYSFGIVLLEIITGQP 780 Query 1100 SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 + K ++ A+ + + +++R + L C ++ R Sbjct 781 VIEQSRDKSY-IVEWAKSMLANGDIESIMDRNLHQDYDTSSSWKALELAMLCINPSSTLR 839 Query 1160 PTFENLIPILKTVHEKYQ 1177 P + L E Y Sbjct 840 PNMTRVAHELNECLEIYN 857 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 76/395 (19%), Positives = 138/395 (35%), Gaps = 63/395 (16%) Query 508 EQQDGAFVLEGWGRSFPSVRELGAA--LQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMR 565 E DG +L G + + + A+ + F RR ++S ++R Sbjct 508 ENNDGLKLLRGKHQPKSWLVAIVASISCVAVTIIVLVLIFIFRR------RKSSTRKVIR 561 Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 + + + + V + LG+G VY G L E Sbjct 562 PSLE----MKNRRFKYSEVKEMTNNFEVVLGKGGFGVVYHGFLNNE-------------- 603 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 +V +KVL S F L+ +V H +L + G C +G + + Sbjct 604 ------------QVAVKVLSQSSTQGYKEFKTEVELLLRVHHVNLVSLVGYCDKGNDLAL 651 Query 686 VTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNI 740 + E++E+G L L +RG + W ++ +A + A + YL +VH +V NI Sbjct 652 IYEFMENGNLKEHLSGKRGGPVLNWPGRLKIAIESALGIEYLHIGCKPPMVHRDVKSTNI 711 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTA 794 LL G KL+D G+ L + + +L PE N L+ Sbjct 712 LL-------GLRFEAKLADFGLSRSFLVGSQTHVSTNVAGTLGYLDPEYYQ--KNWLTEK 762 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854 D + FG LLEI P+ +S + + L + ++ + L + Sbjct 763 SDVYSFGIVLLEIITG--QPVIEQSRDKSYIVEWAKSMLANG---DIESIMDRNLHQDYD 817 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 S++ + + + P + ++ Sbjct 818 TSSSWKALELAMLCINPSSTLRPNMTRVAHELNEC 852 >sp|Q5JLQ9|CIPKU_ORYSJ CBL-interacting protein kinase 30 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK30 PE=2 SV=1 Length=476 Score = 224 bits (570), Expect = 2e-62, Method: Composition-based stats. Identities = 67/269 (25%), Positives = 106/269 (39%), Gaps = 27/269 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960 LG G F KV Y TGE VA+K + + K+E+D++R ++H H+I Sbjct 23 LGRGTFAKV----YKAYKLATGEAVAIKVFDKEAVQRSGTVEQVKREVDVMRRVHHRHVI 78 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019 + + + VMEY G L L R + QQ+ + + H++ Sbjct 79 RLHEVMATRS--RIYFVMEYASGGELFTRLSRSPRFPEPVARRYFQQLITAVEFCHSRGV 136 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 HRDL N+LLD +K+ DFGL+ A+ G + + APE L + + Sbjct 137 YHRDLKPENLLLDARGDLKVTDFGLS-ALDGGLRGDGLLHTTCGTPAYVAPEVLLKRGYD 195 Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 +D+WS GV L+ LL P L+ + + + E R P Sbjct 196 GAKADIWSCGVILFVLLAG-----YLPFNETNLVILYRN---------ITESNYR--CPP 239 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIP 1167 E L+ + R T ++ Sbjct 240 WFSVEARKLLARLLDPNPKTRITISKIMD 268 Score = 181 bits (458), Expect = 2e-47, Method: Composition-based stats. Identities = 54/298 (18%), Positives = 88/298 (30%), Gaps = 42/298 (14%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 LG+GT VY+ G V +KV D Sbjct 18 KLGRLLGRGTFAKVYKAYKLATGE------------------------AVAIKVFDKEAV 53 Query 650 D---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 +M +V H H+ +H V V EY G L L R Sbjct 54 QRSGTVEQVKREVDVMRRVHHRHVIRLHEVMATRSRIYFVMEYASGGELFTRLSRS-PRF 112 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--- 763 P QQL +A+ + ++ + H ++ N+LL G +K++D G+ Sbjct 113 PEPVARRYFQQLITAVEFCHSRGVYHRDLKPENLLLDARGD-------LKVTDFGLSALD 165 Query 764 ---LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 G ++APE L D W G L + ++ Sbjct 166 GGLRGDGLLHTTCGTPAYVAPEVLLKRGYD-GAKADIWSCGVILFVLLAGYLPFNETNLV 224 Query 821 SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + +R P + L ++ L P R + I+ Q + Sbjct 225 ILYRNITESNYRCPPWFSVEARKLLARLLDPNPKTRITISKIMDRPWFQQATCPLGDM 282 >sp|Q9FIF1|LRK21_ARATH Probable L-type lectin-domain containing receptor kinase II.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK21 PE=2 SV=1 Length=674 Score = 229 bits (584), Expect = 3e-62, Method: Composition-based stats. Identities = 72/299 (24%), Positives = 126/299 (42%), Gaps = 19/299 (6%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 +P + + ++ + LG G FGKV +G +AVK + D Q Sbjct 338 YSPQRYSFRILYKATKGFRENQLLGAGGFGKVYKGIL-----PSGTQIAVKRVYHDA-EQ 391 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----I 995 + EI + L H++++ G C +GE L LV +Y+P GSL DYL + + Sbjct 392 GMKQYVAEIASMGRLRHKNLVHLLGYCRRKGE--LLLVYDYMPNGSLDDYLFHKNKLKDL 449 Query 996 GLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 +Q + + + + YLH + +HRD+ A N+LLD D K+GDFGLA+ G Sbjct 450 TWSQRVNIIKGVASALLYLHEEWEQVVLHRDIKASNILLDADLNGKLGDFGLARFHDRGV 509 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLEL 1111 R + + APE +DV++FG + E++ P + + L Sbjct 510 NLEATR--VVGTIGYMAPELTAMGVTTTCTDVYAFGAFILEVVCGRRPVDPDAPREQVIL 567 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + LT+ ++ + ++ + L C + RP+ ++ L+ Sbjct 568 VKWVASCGKRDALTDTVDSKLIDFKVEEAKL-LLKLGMLCSQINPENRPSMRQILQYLE 625 Score = 218 bits (555), Expect = 1e-58, Method: Composition-based stats. Identities = 67/308 (22%), Positives = 112/308 (36%), Gaps = 62/308 (20%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 K + LG G VY+G L ++ +K + Sbjct 351 ATKGFRENQLLGAGGFGKVYKGIL-------------------------PSGTQIAVKRV 385 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + + M ++ H +L + G C R E ++V +Y+ +G LD +L + Sbjct 386 YHDAEQGMKQYVAEIASMGRLRHKNLVHLLGYCRRKGELLLVYDYMPNGSLDDYLFHKNK 445 Query 705 HVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + W ++ + + +ASAL YL + ++H ++ NILL KL D Sbjct 446 LKDLTWSQRVNIIKGVASALLYLHEEWEQVVLHRDIKASNILLD-------ADLNGKLGD 498 Query 760 PGVGLGA-----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ L V I ++APE G +T D + FGA +LE+ G P Sbjct 499 FGLARFHDRGVNLEATRVVGTIGYMAPELTAMGVT--TTCTDVYAFGAFILEVVC-GRRP 555 Query 815 LQSRSPSEKEHF------YQRQHRLPEPSCPQLAT-----------LTSQCLTYEPTQRP 857 + +P E+ ++ L + +L L C P RP Sbjct 556 VDPDAPREQVILVKWVASCGKRDALTDTVDSKLIDFKVEEAKLLLKLGMLCSQINPENRP 615 Query 858 SFRTILRD 865 S R IL+ Sbjct 616 SMRQILQY 623 >sp|A1D2C9|HOG1_NEOFI Mitogen-activated protein kinase hog1 OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=hog1 PE=3 SV=1 Length=366 Score = 220 bits (561), Expect = 3e-62, Method: Composition-based stats. Identities = 70/293 (24%), Positives = 112/293 (38%), Gaps = 31/293 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + TG+ VAVK + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SARDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHE 1174 L + ER P + E L++ + R + L H+ Sbjct 252 SLPKRERQPLANKFKNADPEAVDLLERMLVFDPKKRIRAGEALAHEYLTPYHD 304 Score = 134 bits (336), Expect = 2e-32, Method: Composition-based stats. Identities = 36/231 (16%), Positives = 74/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + RD+ V +K ++ P ++ Y Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSARDQLTGQPVAVKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q5B4Z3|SEPH_EMENI Cytokinesis protein sepH OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=sepH PE=3 SV=2 Length=1346 Score = 237 bits (604), Expect = 3e-62, Method: Composition-based stats. Identities = 75/267 (28%), Positives = 113/267 (42%), Gaps = 28/267 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG G FG V Y N TGE VAVK +K AD EID+L+ L H +I+K Sbjct 66 LGRGAFGSV----YRALNWNTGETVAVKQIKLADLPKSELRVIMLEIDLLKNLDHPNIVK 121 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 Y+G + ++L +++EY GSL + ++ Q+ G+ YLH Q I Sbjct 122 YQGFV--KSAETLNIILEYCENGSLHSIAKNFGRFPETLVGVYMSQVLHGLLYLHDQGVI 179 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ N+L + LVK+ DFG+A +W APE ++ Sbjct 180 HRDIKGANILTTKEGLVKLADFGVA-----SRTTGLSESSVVGTPYWMAPEVIELSGATT 234 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ASD+WS G T+ ELL + Q + R+ + P P Sbjct 235 ASDIWSLGCTVIELLEGKPPYYN-----------LQPMPALFRIV----NDDHPPLPQGA 279 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIP 1167 V + C++ + + R + L+ Sbjct 280 SPAVKDFLMQCFQKDPNLRVSARKLLK 306 Score = 207 bits (528), Expect = 4e-53, Method: Composition-based stats. Identities = 63/290 (22%), Positives = 105/290 (36%), Gaps = 41/290 (14%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 K+ LG+G +VY G V +K + Sbjct 58 KDYQLGDCLGRGAFGSVYRALNWNTGE------------------------TVAVKQIKL 93 Query 647 SH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + L+ + H ++ G ++ EY E+G L + + G Sbjct 94 ADLPKSELRVIMLEIDLLKNLDHPNIVKYQGFVKSAETLNIILEYCENGSLHS-IAKNFG 152 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763 P V Q+ L YL ++ ++H ++ G NIL + GL +KL+D GV Sbjct 153 RFPETLVGVYMSQVLHGLLYLHDQGVIHRDIKGANILTTKEGL-------VKLADFGVAS 205 Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 LS V W+APE + + +TA D W G T++E+ +G+ P + P Sbjct 206 RTTGLSESSVVGTPYWMAPEVIE--LSGATTASDIWSLGCTVIELL-EGKPPYYNLQPMP 262 Query 823 KEH--FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 LP+ + P + QC +P R S R +L+ + Sbjct 263 ALFRIVNDDHPPLPQGASPAVKDFLMQCFQKDPNLRVSARKLLKHPWIVN 312 >sp|Q9LP51|CIPKI_ARATH CBL-interacting serine/threonine-protein kinase 18 OS=Arabidopsis thaliana OX=3702 GN=CIPK18 PE=1 SV=1 Length=520 Score = 225 bits (573), Expect = 3e-62, Method: Composition-based stats. Identities = 69/313 (22%), Positives = 125/313 (40%), Gaps = 26/313 (8%) Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYD 917 +L + + ++ +P SP S + + LG G F KV L Sbjct 35 YMADLLGRIGIMDTDKDGNISPQSPRSPRSPRNNILMGKYELGKLLGHGTFAKVYL---- 90 Query 918 PTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 N +G+ VA+K + + + + K+EI ILR + H +I+ + + + Sbjct 91 AQNIKSGDKVAIKVIDKEKIMKSGLVAHIKREISILRRVRHPYIVHLFEVMATKSK--IY 148 Query 976 LVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDR 1035 VMEYV G L + + + + + QQ+ +++ H + HRDL N+LLDN Sbjct 149 FVMEYVGGGELFNTVAKGRLPEETARRYFQQLISSVSFCHGRGVYHRDLKPENLLLDNKG 208 Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYEL 1094 +K+ DFGL+ + + +P + APE L + +DVWS GV L+ L Sbjct 209 NLKVSDFGLSAVAEQLRQDGLCHTFCGTPA-YIAPEVLTRKGYDAAKADVWSCGVILFVL 267 Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154 + ++ + + + +GE P ++ L+ +T Sbjct 268 MAGHIPFYD---------------KNIMVMYKKIYKGE-FRCPRWFSSDLVRLLTRLLDT 311 Query 1155 EASFRPTFENLIP 1167 R T ++ Sbjct 312 NPDTRITIPEIMK 324 Score = 178 bits (452), Expect = 2e-46, Method: Composition-based stats. Identities = 57/332 (17%), Positives = 104/332 (31%), Gaps = 45/332 (14%) Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 + SP++ + + + + LG GT VY + G Sbjct 50 KDGNISPQSPRSPRSPRNNILMGKYELGKLLGHGTFAKVYLAQNIKSGD----------- 98 Query 625 DPLVPGRDRGQELRVVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 +V +KV+D + S++ +V H ++ + V Sbjct 99 -------------KVAIKVIDKEKIMKSGLVAHIKREISILRRVRHPYIVHLFEVMATKS 145 Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 + V EYV G L +G +P QQL S++S+ + + H ++ N+L Sbjct 146 KIYFVMEYVGGGELFN--TVAKGRLPEETARRYFQQLISSVSFCHGRGVYHRDLKPENLL 203 Query 742 LARLGLAEGTSPFIKLSDPGVG------LGALSREERVERIPWLAPECLPGGANSLSTAM 795 L G +K+SD G+ ++APE L + Sbjct 204 LDNKG-------NLKVSDFGLSAVAEQLRQDGLCHTFCGTPAYIAPEVLTRKGYD-AAKA 255 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPT 854 D W G L + G P ++ + R P L L ++ L P Sbjct 256 DVWSCGVIL-FVLMAGHIPFYDKNIMVMYKKIYKGEFRCPRWFSSDLVRLLTRLLDTNPD 314 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 R + I+++ + + Sbjct 315 TRITIPEIMKNRWFKKGFKHVKFYIEDDKLCR 346 >sp|Q5R754|CDKL2_PONAB Cyclin-dependent kinase-like 2 OS=Pongo abelii OX=9601 GN=CDKL2 PE=2 SV=1 Length=493 Score = 224 bits (571), Expect = 3e-62, Method: Composition-based stats. Identities = 75/283 (27%), Positives = 119/283 (42%), Gaps = 27/283 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG +G V N TG +VA+K L++D + +EI +L+ L HE+++ Sbjct 10 VGEGSYGMVM----KCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 C + +K LV E+V L D L + + + + QI G+ + H+ + I Sbjct 66 LLEVC--KKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNII 123 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFY 1079 HRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L K+ Sbjct 124 HRDIKPENILVSKSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVKYG 180 Query 1080 YASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 A DVW+ G + E+ DS + +G + L + G RL Sbjct 181 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFYKNPVFAGVRL 240 Query 1135 P----------RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P R K V L K C + RP L+ Sbjct 241 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLH 283 Score = 162 bits (409), Expect = 6e-41, Method: Composition-based stats. Identities = 56/320 (18%), Positives = 101/320 (32%), Gaps = 70/320 (22%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-L 644 ++ L +G+G+ V + R + G V +K L Sbjct 1 MEKYENLGLVGEGSYGMVMKCRNKDTGR------------------------IVAIKKFL 36 Query 645 DPSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + + L+ Q+ H +L + VC + +V E+V+H LD L Sbjct 37 ESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDD-LELFP 95 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + Q+ + + + + N++H ++ NIL+++ G+ +KL D G Sbjct 96 NGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSKSGV-------VKLCDFGFA 148 Query 764 LGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + + V + APE L G A+D W G + E+ Sbjct 149 RTLAAPGEVYTDYVATRWYRAPELLV-GDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSD 207 Query 820 PSEKEHFYQ-------------------RQHRLPEPS------------CPQLATLTSQC 848 + H RLPE + L +C Sbjct 208 IDQLYHIMMCLGNLIPRHQELFYKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKC 267 Query 849 LTYEPTQRPSFRTILRDLTR 868 L +P +RP +L Sbjct 268 LHIDPDKRPFCAELLHHDFF 287 >sp|Q9SCZ4|FERON_ARATH Receptor-like protein kinase FERONIA OS=Arabidopsis thaliana OX=3702 GN=FER PE=1 SV=1 Length=895 Score = 233 bits (594), Expect = 3e-62, Method: Composition-based stats. Identities = 79/315 (25%), Positives = 131/315 (42%), Gaps = 19/315 (6%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 + + + R LG G FGKV D GT VA+K Q Sbjct 521 CRHFSFAEIKAATKNFDESRVLGVGGFGKVYRGEIDG---GT-TKVAIKRGNP-MSEQGV 575 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLA 998 ++ EI++L L H H++ G CE+ E + LV +Y+ G++R++L S+ Sbjct 576 HEFQTEIEMLSKLRHRHLVSLIGYCEENCE--MILVYDYMAHGTMREHLYKTQNPSLPWK 633 Query 999 QLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 Q L G+ YLH IHRD+ N+LLD + K+ DFGL+K P ++ Sbjct 634 QRLEICIGAARGLHYLHTGAKHTIIHRDVKTTNILLDEKWVAKVSDFGLSKTGP-TLDHT 692 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 V + PE + + SDV+SFGV L+E L C PT E + +A Sbjct 693 HVSTVVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLFEAL--CARPALNPTLAKEQVSLA 750 Query 1116 QGQMTVLR---LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + + L ++++ + +C + C + RP+ +++ L+ Sbjct 751 EWAPYCYKKGMLDQIVDPYLKGKITPECFKKFAETAMKCVLDQGIERPSMGDVLWNLEFA 810 Query 1173 HEKYQGQAPSVFSVC 1187 + + + VC Sbjct 811 LQLQESAEENGKGVC 825 Score = 218 bits (554), Expect = 4e-57, Method: Composition-based stats. Identities = 68/312 (22%), Positives = 108/312 (35%), Gaps = 52/312 (17%) Query 559 SNLIIMRGARASPRTLNL-SQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615 S G+ AS NL SF + K + LG G VY G + Sbjct 503 SAKTNTTGSYASSLPSNLCRHFSFAEIKAATKNFDESRVLGVGGFGKVYRGEI------- 555 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675 G +V +K +P F ++S++ H HL + G Sbjct 556 -----------------DGGTTKVAIKRGNPMSEQGVHEFQTEIEMLSKLRHRHLVSLIG 598 Query 676 VCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLE---NKNLV 731 C E I+V +Y+ HG + L + + +P ++ + A L YL ++ Sbjct 599 YCEENCEMILVYDYMAHGTMREHLYKTQNPSLPWKQRLEICIGAARGLHYLHTGAKHTII 658 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVERI-----PWLAPECLP 785 H +V NILL +A K+SD G+ G V + +L PE Sbjct 659 HRDVKTTNILLDEKWVA-------KVSDFGLSKTGPTLDHTHVSTVVKGSFGYLDPEYFR 711 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSR-----SPSEKEHFYQRQHRLPEPSCPQ 840 L+ D + FG L E A + S +E + ++ L + P Sbjct 712 --RQQLTEKSDVYSFGVVLFEALCARPALNPTLAKEQVSLAEWAPYCYKKGMLDQIVDPY 769 Query 841 LA-TLTSQCLTY 851 L +T +C Sbjct 770 LKGKITPECFKK 781 >sp|Q6FN53|STE20_CANGA Serine/threonine-protein kinase STE20 OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=STE20 PE=3 SV=1 Length=915 Score = 233 bits (595), Expect = 3e-62, Method: Composition-based stats. Identities = 62/282 (22%), Positives = 120/282 (43%), Gaps = 25/282 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G G V + + + + VA+K + + P+ + EI ++R H +I+ Sbjct 625 KIGQGASGGVYIAH----DTESEDSVAIKQMNLEKQPK-KELILNEILVMRESKHSNIVN 679 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 + +G+ L +VMEY+ GSL D + + Q+ ++ +G+ +LH++ +H Sbjct 680 FIDSYLAKGD--LWIVMEYMEGGSLTDVVTHCLLSEGQIGAVCRETLKGLQFLHSKGVLH 737 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RD+ + N+LL +K+ DFG + E + R +W APE + ++ Sbjct 738 RDIKSDNILLSLKGNIKLTDFGFCAQINENNL---KRTTMVGTPYWMAPEVVSRKEYGPK 794 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 D+WS G+ + E++ + T L IA +L P+ Sbjct 795 VDIWSLGIMIIEMI-EGEPPYLNETPLRALYLIATNGTP------------KLKEPEALS 841 Query 1142 CEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAP 1181 + + C + + S R T L+ P + + E +P Sbjct 842 DTLTKFLDWCLKVDPSERATATELLDDPFITEIAEDNSSLSP 883 Score = 187 bits (474), Expect = 4e-47, Method: Composition-based stats. Identities = 56/295 (19%), Positives = 101/295 (34%), Gaps = 44/295 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L+++ + + L +GQG VY D Sbjct 607 LTEICSPGDPKSKYRDLIKIGQGASGGVY------------------------IAHDTES 642 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 E V +K ++ +M + H+++ + + +V EY+E G L Sbjct 643 EDSVAIKQMNLEKQPKKELILNEILVMRESKHSNIVNFIDSYLAKGDLWIVMEYMEGGSL 702 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 + + V ++ L +L +K ++H ++ NILL+ G I Sbjct 703 TDVVTH--CLLSEGQIGAVCRETLKGLQFLHSKGVLHRDIKSDNILLSLKG-------NI 753 Query 756 KLSDPGVGLGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D G L R V W+APE + +D W G ++E+ +G Sbjct 754 KLTDFGFCAQINENNLKRTTMVGTPYWMAPEVVS--RKEYGPKVDIWSLGIMIIEMI-EG 810 Query 812 EAPLQSRSPSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 E P + +P + PE L CL +P++R + + Sbjct 811 EPPYLNETPLRALYLIATNGTPKLKEPEALSDTLTKFLDWCLKVDPSERATATEL 865 >sp|Q68Y49|CIPKJ_ORYSJ CBL-interacting protein kinase 19 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK19 PE=1 SV=1 Length=508 Score = 224 bits (572), Expect = 3e-62, Method: Composition-based stats. Identities = 63/270 (23%), Positives = 108/270 (40%), Gaps = 30/270 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960 LG G F KV Y + +GE VA+K L + +H K+EI ILR + H +I+ Sbjct 43 LGHGTFAKV----YQARSADSGEPVAIKVLDKEKAMRHGLVPHIKREIAILRRVRHPNIV 98 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + + + + VME V G L + + + + QQ+ + + HA+ Sbjct 99 RLFEVMATKSK--IYFVMELVRGGELFGRVAKGRLKEDTARRYFQQLVSAVGFCHARGVF 156 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 HRDL N+L+D +K+ DFGL+ + H + +P + APE L + Sbjct 157 HRDLKPENLLVDEHGDLKVSDFGLSAVADQFHPDGLLHTFCGTPS-YVAPEVLARRGYDG 215 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP--RP 1137 +D+WS G+ L+ L+ L + + R P Sbjct 216 AKADIWSCGIILFVLMAGYLPFHD------------------QNLMAMYRKIYRGEFRCP 257 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 ++ L+ +T R T + ++ Sbjct 258 RWFSKDLSSLLNRILDTNPETRITVKEVME 287 Score = 180 bits (456), Expect = 6e-47, Method: Composition-based stats. Identities = 54/305 (18%), Positives = 94/305 (31%), Gaps = 43/305 (14%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH- 648 LG GT VY+ R G V +KVLD Sbjct 38 ELGRLLGHGTFAKVYQARSADSGE------------------------PVAIKVLDKEKA 73 Query 649 --HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 H + +++ +V H ++ + V + V E V G L R +G + Sbjct 74 MRHGLVPHIKREIAILRRVRHPNIVRLFEVMATKSKIYFVMELVRGGELFG--RVAKGRL 131 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 QQL SA+ + + + H ++ N+L+ G +K+SD G+ A Sbjct 132 KEDTARRYFQQLVSAVGFCHARGVFHRDLKPENLLVDEHGD-------LKVSDFGLSAVA 184 Query 767 LS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 ++APE L D W G L + Sbjct 185 DQFHPDGLLHTFCGTPSYVAPEVLARRGYD-GAKADIWSCGIILFVLMAGYLPFHDQNLM 243 Query 821 SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880 + Y+ + R P L++L ++ L P R + + ++ + Sbjct 244 AMYRKIYRGEFRCPRWFSKDLSSLLNRILDTNPETRITVKEVMESRWFQKGFRPVRFYVE 303 Query 881 NPDSP 885 + Sbjct 304 DDQVH 308 >sp|P52497|SNF1_CANAX Carbon catabolite-derepressing protein kinase OS=Candida albicans OX=5476 GN=SNF1 PE=2 SV=2 Length=620 Score = 228 bits (580), Expect = 3e-62, Method: Composition-based stats. Identities = 77/327 (24%), Positives = 123/327 (38%), Gaps = 30/327 (9%) Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 S+ + + H+ + + + ++ LG Sbjct 1 MSEQAQPQASADQQQHQHNHHHHHHHHHHNENQSQQQVPIDPAANPANRIGRYQILKTLG 60 Query 905 EGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG--WKQEIDILRTLYHEHIIKY 962 EG FGKV L + GTG+ VA+K + + ++EI LR L H HIIK Sbjct 61 EGSFGKVKL----AQHLGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHPHIIKL 116 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 + + E + +V+E+ L DY+ R + + F QQI + Y H +H Sbjct 117 YDVIKSKDE--IIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHKIVH 173 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF-YY 1080 RDL N+LLD+ VKI DFGL+ + +G+ ++ SP + APE + + Sbjct 174 RDLKPENLLLDDQLNVKIADFGLSNIMTDGN---FLKTSCGSPNYMPAPEVISGKLYAGP 230 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 DVWS GV LY +L + L + + G P+ Sbjct 231 EVDVWSAGVILYVMLCGRLPFDDEF---------------IPALFKKISNGV-YTLPNYL 274 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIP 1167 HL+ R T ++ Sbjct 275 SAGAKHLLTRMLVVNPLNRITIHEIME 301 Score = 176 bits (445), Expect = 1e-44, Method: Composition-based stats. Identities = 54/298 (18%), Positives = 98/298 (33%), Gaps = 37/298 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +R+ + +I L LG+G+ V + G + Sbjct 48 NRIGRYQI--LKTLGEGSFGKVKLAQHLGTGQKVALKIINR------------------- 86 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 K L S + S + + H H+ ++ V E IMV E+ L ++ Sbjct 87 KTLAKSDMQGRVE--REISYLRLLRHPHIIKLYDVIKSKDEIIMVIEFA-GKELFDYI-V 142 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 +RG +P QQ+ +A+ Y +VH ++ N+LL +K++D G Sbjct 143 QRGKMPEDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLLLDDQL-------NVKIADFG 195 Query 762 VGLGALSR---EERVERIPWL-APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + + ++ APE + G + +D W G L + Sbjct 196 LSNIMTDGNFLKTSCGSPNYMPAPEVISGKLYA-GPEVDVWSAGVILYVMLCGRLPFDDE 254 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 P+ + + LP L ++ L P R + I+ D Q Sbjct 255 FIPALFKKISNGVYTLPNYLSAGAKHLLTRMLVVNPLNRITIHEIMEDDWFKQDMPDY 312 >sp|Q9S9U1|LRK71_ARATH L-type lectin-domain containing receptor kinase VII.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK71 PE=2 SV=1 Length=686 Score = 229 bits (584), Expect = 3e-62, Method: Composition-based stats. Identities = 66/305 (22%), Positives = 122/305 (40%), Gaps = 23/305 (8%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + P + + + +G G GKV Y G VAVK + + Sbjct 328 MEYWPHRIPYEEIESGTKGFDEKNVIGIGGNGKV----YKGLLQGGVVEVAVKRISQESS 383 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---- 993 R + EI L L H +++ +G C+ + S LV +Y+ GSL ++ + Sbjct 384 DGMRE-FVAEISSLGRLKHRNLVSLRGWCK-KEVGSFMLVYDYMENGSLDRWIFENDEKI 441 Query 994 -SIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 ++ + + + + G+ YLH +HRD+ A NVLLD D + ++ DFGLA+ Sbjct 442 TTLSCEERIRILKGVASGILYLHEGWESKVLHRDIKASNVLLDRDMIPRLSDFGLARV-- 499 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 GHE + APE +K + +DV+++G+ + E++ + Sbjct 500 HGHEQPVRTTRVVGTAGYLAPEVVKTGRASTQTDVFAYGILVLEVMCGRRPIEEGKKP-- 557 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPD----KCPCEVYHLMKNCWETEASFRPTFENL 1165 L+ G M + L+ + + V L C + + RP+ + Sbjct 558 -LMDWVWGLMERGEILNGLDPQMMMTQGVTEVIDEAERVLQLGLLCAHPDPAKRPSMRQV 616 Query 1166 IPILK 1170 + + + Sbjct 617 VQVFE 621 Score = 198 bits (503), Expect = 9e-52, Method: Composition-based stats. Identities = 60/317 (19%), Positives = 114/317 (36%), Gaps = 69/317 (22%) Query 582 HRVDQKEIT-------QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 HR+ +EI + + +G G VY+G L +G Sbjct 333 HRIPYEEIESGTKGFDEKNVIGIGGNGKVYKGLL------------------------QG 368 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHG 693 + V +K + D F S + ++ H +L + G C + ++V +Y+E+G Sbjct 369 GVVEVAVKRISQESSDGMREFVAEISSLGRLKHRNLVSLRGWCKKEVGSFMLVYDYMENG 428 Query 694 PLDVWLRRERGHVPM---AWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGL 747 LD W+ + ++ + + +AS + YL ++H ++ N+LL R + Sbjct 429 SLDRWIFENDEKITTLSCEERIRILKGVASGILYLHEGWESKVLHRDIKASNVLLDRDMI 488 Query 748 AEGTSPFIKLSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 +LSD G+ + V +LAPE + G ST D + +G Sbjct 489 P-------RLSDFGLARVHGHEQPVRTTRVVGTAGYLAPEVVKTGRA--STQTDVFAYGI 539 Query 803 TLLEICFDGEAPLQSRSP-----------------SEKEHFYQRQHRLPEPSCPQLATLT 845 +LE+ + + P + + + ++ L Sbjct 540 LVLEVMCGRRPIEEGKKPLMDWVWGLMERGEILNGLDPQMMMTQGVTEVIDEAERVLQLG 599 Query 846 SQCLTYEPTQRPSFRTI 862 C +P +RPS R + Sbjct 600 LLCAHPDPAKRPSMRQV 616 >sp|Q09092|SRK6_BRAOV Putative serine/threonine-protein kinase receptor OS=Brassica oleracea var. viridis OX=3713 GN=SRK6 PE=1 SV=2 Length=857 Score = 232 bits (592), Expect = 3e-62, Method: Composition-based stats. Identities = 67/302 (22%), Positives = 115/302 (38%), Gaps = 24/302 (8%) Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G FG V G+ +AVK L Q + E+ ++ L H ++ Sbjct 531 CNKLGQGGFGIVYKGRL-----LDGKEIAVKRLSK-TSVQGTDEFMNEVTLIARLQHINL 584 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015 ++ GCC + EK L+ EY+ SL YL R + + + G+ YLH Sbjct 585 VQVLGCCIEGDEK--MLIYEYLENLSLDSYLFGKTRRSKLNWNERFDITNGVARGLLYLH 642 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 IHRDL N+LLD + + KI DFG+A+ + + +PE Sbjct 643 QDSRFRIIHRDLKVSNILLDKNMIPKISDFGMARIFERDETEANTMK-VVGTYGYMSPEY 701 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQ----SPPTKFLELIGIAQGQMTVLRLTELL 1128 F SDV+SFGV + E+++ + L + + L + + + Sbjct 702 AMYGIFSEKSDVFSFGVIVLEIVSGKKNRGFYNLDYENDLLSYVWSRWKEGRALEIVDPV 761 Query 1129 ERGERLPRPDKCPC----EVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 +P + + C + A RP +++ + + + P + Sbjct 762 IVDSLSSQPSIFQPQEVLKCIQIGLLCVQELAEHRPAMSSVVWMFGSEATEIPQPKPPGY 821 Query 1185 SV 1186 V Sbjct 822 CV 823 Score = 226 bits (576), Expect = 4e-60, Method: Composition-based stats. Identities = 62/350 (18%), Positives = 114/350 (33%), Gaps = 53/350 (15%) Query 559 SNLIIMRGARASPRTLNLSQLSFHRVD-------QKEITQLSHLGQGTRTNVYEGRLRVE 611 N +++ R +L ++ + + + LGQG VY+GRL Sbjct 491 MNEMVLSSKREFSGEYKFEELELPLIEMETVVKATENFSSCNKLGQGGFGIVYKGRLLDG 550 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 + +K L + F +L++++ H +L Sbjct 551 K-------------------------EIAVKRLSKTSVQGTDEFMNEVTLIARLQHINLV 585 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRR--ERGHVPMAWKMVVAQQLASALSYLENK- 728 V G C+ G E +++ EY+E+ LD +L R + + + +A L YL Sbjct 586 QVLGCCIEGDEKMLIYEYLENLSLDSYLFGKTRRSKLNWNERFDITNGVARGLLYLHQDS 645 Query 729 --NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLA 780 ++H ++ NILL + + K+SD G+ E V +++ Sbjct 646 RFRIIHRDLKVSNILLDK-------NMIPKISDFGMARIFERDETEANTMKVVGTYGYMS 698 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ 840 PE G S D + FG +LEI + E + R E + Sbjct 699 PEYAMYGI--FSEKSDVFSFGVIVLEIVSGKKNRGFYNLDYENDLLSYVWSRWKEGRALE 756 Query 841 LAT-LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 + + L+ +P+ + L S Sbjct 757 IVDPVIVDSLSSQPSIFQPQEVLKCIQIGLLCVQELAEHRPAMSSVVWMF 806 >sp|Q9ES70|NEK6_MOUSE Serine/threonine-protein kinase Nek6 OS=Mus musculus OX=10090 GN=Nek6 PE=1 SV=1 Length=313 Score = 218 bits (555), Expect = 3e-62, Method: Composition-based stats. Identities = 61/285 (21%), Positives = 116/285 (41%), Gaps = 30/285 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTL 954 + + +G G F +V Y T + VA+K ++ + R +EI +L+ L Sbjct 45 FQIEKKIGRGQFSEV----YKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQL 100 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICE 1009 H +IIKY + E L +V+E G L + + I + + Q+C Sbjct 101 NHPNIIKYLDSFIEDNE--LNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCS 158 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + ++H++ +HRD+ NV + +VK+GD GL + ++ + Sbjct 159 AVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFS---SETTAAHSLVGTPYYMS 215 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE + E + + SD+WS G LYE+ +M + L + +E Sbjct 216 PERIHENGYNFKSDIWSLGCLLYEMAALQSPFYG-------------DKMNLFSLCQKIE 262 Query 1130 RGERLPRP-DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + + P P + ++ L+ C + RP + + + +H Sbjct 263 QCDYPPLPGEHYSEKLRELVSMCIYPDPDHRPDIVYVHQVARQMH 307 Score = 171 bits (433), Expect = 8e-46, Method: Composition-based stats. Identities = 53/332 (16%), Positives = 108/332 (33%), Gaps = 41/332 (12%) Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 +P G ++L G P L R + +G+G + VY+ ++ Sbjct 8 MPHGGSPNHLCHALGPAPPPDPQRLPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLD 67 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 + E R +K L+ Q++H ++ Sbjct 68 RKTVALKKVQIFEMMDAKARQD------CVK---------------EIGLLKQLNHPNII 106 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDV---WLRRERGHVPMAWKMVVAQQLASALSYLENK 728 + E +V E + G L + ++++ +P QL SA+ ++ ++ Sbjct 107 KYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSR 166 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER----VERIPWLAPECL 784 ++H ++ N+ + G+ +KL D G+G S V +++PE + Sbjct 167 RVMHRDIKPANVFITATGI-------VKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERI 219 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS----EKEHFYQRQHRLPEPSCPQ 840 + D W G L E+ + +K E + Sbjct 220 HENGYNF--KSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEK 277 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 L L S C+ +P RP + + ++ Sbjct 278 LRELVSMCIYPDPDHRPDIVYVHQVARQMHVW 309 >sp|P38692|KIC1_YEAST Serine/threonine-protein kinase KIC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=KIC1 PE=1 SV=1 Length=1080 Score = 235 bits (599), Expect = 3e-62, Method: Composition-based stats. Identities = 70/269 (26%), Positives = 117/269 (43%), Gaps = 29/269 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH-EHIIK 961 +G G FG V Y N TG + A+K L D ++EI L +L +I + Sbjct 29 IGRGKFGVV----YKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITR 84 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 Y G + SL ++ME+ GSLR L I + + +++ + +H + IH Sbjct 85 YYGSYLK--DTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIH 142 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-Y 1080 RD+ A NVL+ N+ VK+ DFG+A V + R+ +W APE + E +Y Sbjct 143 RDIKAANVLITNEGNVKLCDFGVAAQVNQTSLR---RQTMAGTPYWMAPEVIMEGVYYDT 199 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK- 1139 D+WS G+T YE+ T + LR +L+ + + PR + Sbjct 200 KVDIWSLGITTYEIATGNPP---------------YCDVEALRAMQLIIKS-KPPRLEDR 243 Query 1140 -CPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + C + + R + ++L+ Sbjct 244 SYSTSLKEFIALCLDEDPKERLSADDLLK 272 Score = 183 bits (464), Expect = 1e-45, Method: Composition-based stats. Identities = 55/277 (20%), Positives = 98/277 (35%), Gaps = 44/277 (16%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD-PS 647 + +G+G VY+G G +KVL+ S Sbjct 23 FKRTEVIGRGKFGVVYKGYNVKTGRVY------------------------AIKVLNLDS 58 Query 648 HHDIALAFYETASLMSQVSH-THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 D ++ + +++ +G ++ ++ E+ G L LR G + Sbjct 59 DSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLR--PGKI 116 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--- 763 + V+ ++L AL + N++H ++ N+L+ G +KL D GV Sbjct 117 DEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEG-------NVKLCDFGVAAQV 169 Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP-- 820 +L R+ W+APE + G T +D W G T EI G P Sbjct 170 NQTSLRRQTMAGTPYWMAPEVIMEGVY-YDTKVDIWSLGITTYEIA-TGNPPYCDVEALR 227 Query 821 SEKEHFYQRQHRLPEP-SCPQLATLTSQCLTYEPTQR 856 + + + RL + L + CL +P +R Sbjct 228 AMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKER 264 >sp|Q9C8I6|IOS1_ARATH LRR receptor-like serine/threonine-protein kinase IOS1 OS=Arabidopsis thaliana OX=3702 GN=IOS1 PE=1 SV=1 Length=894 Score = 233 bits (594), Expect = 3e-62, Method: Composition-based stats. Identities = 70/306 (23%), Positives = 121/306 (40%), Gaps = 18/306 (6%) Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932 + V + K R LG G FG V E VAVK L Sbjct 562 HHGFEPPVIAKNRKLTYIDVVKITNNFERVLGRGGFGVVYYGVL------NNEPVAVKML 615 Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992 + +K E+++L ++H+ + G CE+ + + L+ E++ G L+++L Sbjct 616 -TESTALGYKQFKAEVELLLRVHHKDLTCLVGYCEEGDK--MSLIYEFMANGDLKEHLSG 672 Query 993 HS----IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 + L A + +G+ YLH +HRD+ N+LL+ K+ DFGL+ Sbjct 673 KRGPSILTWEGRLRIAAESAQGLEYLHNGCKPQIVHRDIKTTNILLNEKFQAKLADFGLS 732 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 ++ P G E + +P + PE + SDV+SFGV L EL+T+ Sbjct 733 RSFPLGTETHVSTIVAGTP-GYLDPEYYRTNWLTEKSDVFSFGVVLLELVTNQPVIDMKR 791 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 K + ++ + +++ + +V C +S RPT + Sbjct 792 EK-SHIAEWVGLMLSRGDINSIVDPKLQGDFDPNTIWKVVETAMTCLNPSSSRRPTMTQV 850 Query 1166 IPILKT 1171 + LK Sbjct 851 VMDLKE 856 Score = 203 bits (516), Expect = 2e-52, Method: Composition-based stats. Identities = 75/346 (22%), Positives = 118/346 (34%), Gaps = 61/346 (18%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 P +L++ V + LG+G VY G L E Sbjct 566 EPPVIAKNRKLTYIDVVKITNNFERVLGRGGFGVVYYGVLNNE----------------- 608 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 V +K+L S F L+ +V H L + G C G + ++ E Sbjct 609 ---------PVAVKMLTESTALGYKQFKAEVELLLRVHHKDLTCLVGYCEEGDKMSLIYE 659 Query 689 YVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLA 743 ++ +G L L +RG + W ++ +A + A L YL N +VH ++ NILL Sbjct 660 FMANGDLKEHLSGKRGPSILTWEGRLRIAAESAQGLEYLHNGCKPQIVHRDIKTTNILLN 719 Query 744 RLGLAEGTSPFIKLSDPGVGLG-ALSREERVERI-----PWLAPECLPGGANSLSTAMDK 797 A KL+D G+ L E V I +L PE N L+ D Sbjct 720 EKFQA-------KLADFGLSRSFPLGTETHVSTIVAGTPGYLDPEYYRT--NWLTEKSDV 770 Query 798 WGFGATLLEICFDGEAPLQSRSPS---EKEHFYQRQHRLPEPSCPQL------------A 842 + FG LLE+ + R S E + + P+L Sbjct 771 FSFGVVLLELVTNQPVIDMKREKSHIAEWVGLMLSRGDINSIVDPKLQGDFDPNTIWKVV 830 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASD 888 CL ++RP+ ++ DL +A + +D Sbjct 831 ETAMTCLNPSSSRRPTMTQVVMDLKECLNMEMARNMGSRMTDSTND 876 >sp|P54666|CC2H3_TRYBB Cell division control protein 2 homolog 3 OS=Trypanosoma brucei brucei OX=5702 GN=CRK3 PE=3 SV=1 Length=311 Score = 218 bits (555), Expect = 3e-62, Method: Composition-based stats. Identities = 70/290 (24%), Positives = 120/290 (41%), Gaps = 29/290 (10%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDIL 951 ++ LGEG +G V Y + TG++VA+K ++ D + +E+ IL Sbjct 19 QFDRYNRMDILGEGTYGVV----YRAVDRATGQIVALKKVRLDRTDEGIPQTALREVSIL 74 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICE 1009 + ++H +I+ G+ L L+ EYV L+ L + L Q+ E Sbjct 75 QEIHHPNIVNLLDVICADGK--LYLIFEYVDH-DLKKALEKRGGAFTGTTLKKIIYQLLE 131 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 G+++ H +HRDL N+L+ D VKI DFGLA+A Y +++ A Sbjct 132 GLSFCHRHRIVHRDLKPANILVTTDNSVKIADFGLARAFQIPMHTY---THEVVTLWYRA 188 Query 1070 PECLKEYK-FYYASDVWSFGVTLYEL-----LTHCDSSQSPPTKFLELIGIA-QGQMTVL 1122 PE L K + A D+WS G EL L DS + +++G + + L Sbjct 189 PEILLGEKHYTPAVDMWSIGCIFAELARGKVLFRGDSEIGQLFEIFQVLGTPMDAEGSWL 248 Query 1123 RLTELLERGERLPRPDKCPC---------EVYHLMKNCWETEASFRPTFE 1163 ++ L + + P+ P + L+ + R + + Sbjct 249 GVSSLPDYRDVFPKWSGKPLTQVLPTLDGDAVDLLSQMLRYNPAERISAK 298 Score = 173 bits (439), Expect = 1e-46, Method: Composition-based stats. Identities = 48/223 (22%), Positives = 80/223 (36%), Gaps = 39/223 (17%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--VLDPSH 648 ++ LG+GT VY DR V LK LD + Sbjct 25 RMDILGEGTYGVVYRAV------------------------DRATGQIVALKKVRLDRTD 60 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 I S++ ++ H ++ + V + ++ EYV+H L L + G Sbjct 61 EGIPQTALREVSILQEIHHPNIVNLLDVICADGKLYLIFEYVDH-DLKKALEKRGGAFTG 119 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG--- 765 + QL LS+ +VH ++ NIL+ T +K++D G+ Sbjct 120 TTLKKIIYQLLEGLSFCHRHRIVHRDLKPANILVT-------TDNSVKIADFGLARAFQI 172 Query 766 -ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 + V + + APE L G + A+D W G E+ Sbjct 173 PMHTYTHEVVTLWYRAPEILL-GEKHYTPAVDMWSIGCIFAEL 214 >sp|Q9LMT9|WAKLL_ARATH Putative wall-associated receptor kinase-like 13 OS=Arabidopsis thaliana OX=3702 GN=WAKL13 PE=3 SV=1 Length=764 Score = 231 bits (588), Expect = 4e-62, Method: Composition-based stats. Identities = 77/301 (26%), Positives = 118/301 (39%), Gaps = 24/301 (8%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R +G+G G V G VAVK + E+ IL + Sbjct 452 DNFNDNRVIGQGGQGTVYKGML-----VDGRSVAVKKSNV-VDEDKLQEFINEVIILSQI 505 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEG 1010 H H++K GCC + E + LV E++P G+L +L ++ + A I Sbjct 506 NHRHVVKLLGCCLE-TEVPI-LVYEFIPNGNLFQHLHEEFDDYTALWGVRMRIAVDISGA 563 Query 1011 MAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 +YLH HRD+ + N+LLD K+ DFG +++V H ++ V + Sbjct 564 FSYLHTAACSPIYHRDIKSTNILLDEKYRAKVSDFGTSRSVSIDHTHWTT--VISGTVGY 621 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLT 1125 PE F SDV+SFGV L EL+T + S + L + M RL Sbjct 622 VDPEYYGSSHFTEKSDVYSFGVVLVELITGEKPVITLSETQEITGLADYFRLAMRENRLF 681 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 E+++ R + V +L C + RP + L+ + AP F Sbjct 682 EIIDARIRNDCKLEQVIAVANLALRCLKKTGKTRPDMREVSTALERIC-----SAPEDFQ 736 Query 1186 V 1186 V Sbjct 737 V 737 Score = 216 bits (550), Expect = 3e-57, Method: Composition-based stats. Identities = 73/378 (19%), Positives = 128/378 (34%), Gaps = 82/378 (22%) Query 536 CLLRAGDDCFSLRRCCLPQP---------GETSNLII------MRGARASPRTLNLSQLS 580 +L G + R+ + L++ +G + + +L Sbjct 389 FVLIVGGGIWWWRKLLRKRRMTNRKRKFFKRNGGLLLQQQLNTTQGRVEKTKLFSSRELE 448 Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 +GQG + VY+G L S V Sbjct 449 K---ATDNFNDNRVIGQGGQGTVYKGMLVDGRS-------------------------VA 480 Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 +K + D F ++SQ++H H+ + G C+ I+V E++ +G L L Sbjct 481 VKKSNVVDEDKLQEFINEVIILSQINHRHVVKLLGCCLETEVPILVYEFIPNGNLFQHLH 540 Query 701 RERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFI 755 E W +M +A ++ A SYL + H ++ NILL A Sbjct 541 EEFDDYTALWGVRMRIAVDISGAFSYLHTAACSPIYHRDIKSTNILLDEKYRA------- 593 Query 756 KLSDPGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K+SD G + ++ PE G++ + D + FG L+E+ Sbjct 594 KVSDFGTSRSVSIDHTHWTTVISGTVGYVDPEYY--GSSHFTEKSDVYSFGVVLVELI-T 650 Query 811 GEAPLQSRSPSEKE-------HFYQRQHRLPEPSCPQL------------ATLTSQCLTY 851 GE P+ + S +++ R++RL E ++ A L +CL Sbjct 651 GEKPVITLSETQEITGLADYFRLAMRENRLFEIIDARIRNDCKLEQVIAVANLALRCLKK 710 Query 852 EPTQRPSFRTILRDLTRL 869 RP R + L R+ Sbjct 711 TGKTRPDMREVSTALERI 728 >sp|P35465|PAK1_RAT Serine/threonine-protein kinase PAK 1 OS=Rattus norvegicus OX=10116 GN=Pak1 PE=1 SV=3 Length=544 Score = 225 bits (574), Expect = 4e-62, Method: Composition-based stats. Identities = 72/370 (19%), Positives = 132/370 (36%), Gaps = 25/370 (7%) Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 P+ + P + Y R P P P + + ++ + R+ + + Sbjct 186 PPVIAPRPEHTKSVYTRSVIEPLPVTPT-RDVATSPISPTENNTTPPDALTRNTEKQKKK 244 Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932 + + K+ + +G+G G V Y + TG+ VA+K + Sbjct 245 PKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV----YTAMDVATGQEVAIKQM 300 Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992 P+ + EI ++R + +I+ Y E L +VMEY+ GSL D + Sbjct 301 NLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTE 357 Query 993 HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 + Q+ ++ + + +LH+ IHRD+ + N+LL D VK+ DFG + Sbjct 358 TCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITP-- 415 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 R +W APE + + D+WS G+ E++ PP + Sbjct 416 -EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI-----EGEPPYLNENPL 469 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP-ILKT 1171 T L P+K + C E + R + + L+ Sbjct 470 RALYLIATNGT--------PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLK 521 Query 1172 VHEKYQGQAP 1181 + + P Sbjct 522 IAKPLSSLTP 531 Score = 181 bits (458), Expect = 6e-47, Method: Composition-based stats. Identities = 54/291 (19%), Positives = 97/291 (33%), Gaps = 44/291 (15%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +K+ T+ +GQG VY D V +K + Sbjct 265 PKKKYTRFEKIGQGASGTVY------------------------TAMDVATGQEVAIKQM 300 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + +M + + ++ + G E +V EY+ G L + Sbjct 301 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 358 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + V ++ AL +L + ++H ++ NILL G +KL+D G Sbjct 359 CMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 411 Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 R V W+APE + A +D W G +E+ +GE P + +P Sbjct 412 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMI-EGEPPYLNENP 468 Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + PE ++CL + +R S + +L+ Sbjct 469 LRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF 519 >sp|Q13153|PAK1_HUMAN Serine/threonine-protein kinase PAK 1 OS=Homo sapiens OX=9606 GN=PAK1 PE=1 SV=2 Length=545 Score = 225 bits (574), Expect = 4e-62, Method: Composition-based stats. Identities = 72/370 (19%), Positives = 132/370 (36%), Gaps = 25/370 (7%) Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 P+ + P + Y R P P P + + ++ + R+ + + Sbjct 187 PPVIAPRPEHTKSVYTRSVIEPLPVTPT-RDVATSPISPTENNTTPPDALTRNTEKQKKK 245 Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932 + + K+ + +G+G G V Y + TG+ VA+K + Sbjct 246 PKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV----YTAMDVATGQEVAIKQM 301 Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992 P+ + EI ++R + +I+ Y E L +VMEY+ GSL D + Sbjct 302 NLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTE 358 Query 993 HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 + Q+ ++ + + +LH+ IHRD+ + N+LL D VK+ DFG + Sbjct 359 TCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITP-- 416 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 R +W APE + + D+WS G+ E++ PP + Sbjct 417 -EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI-----EGEPPYLNENPL 470 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP-ILKT 1171 T L P+K + C E + R + + L+ Sbjct 471 RALYLIATNGT--------PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLK 522 Query 1172 VHEKYQGQAP 1181 + + P Sbjct 523 IAKPLSSLTP 532 Score = 181 bits (458), Expect = 6e-47, Method: Composition-based stats. Identities = 54/291 (19%), Positives = 97/291 (33%), Gaps = 44/291 (15%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +K+ T+ +GQG VY D V +K + Sbjct 266 PKKKYTRFEKIGQGASGTVY------------------------TAMDVATGQEVAIKQM 301 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + +M + + ++ + G E +V EY+ G L + Sbjct 302 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 359 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + V ++ AL +L + ++H ++ NILL G +KL+D G Sbjct 360 CMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 412 Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 R V W+APE + A +D W G +E+ +GE P + +P Sbjct 413 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMI-EGEPPYLNENP 469 Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + PE ++CL + +R S + +L+ Sbjct 470 LRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF 520 >sp|Q03497|STE20_YEAST Serine/threonine-protein kinase STE20 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=STE20 PE=1 SV=1 Length=939 Score = 233 bits (595), Expect = 4e-62, Method: Composition-based stats. Identities = 62/282 (22%), Positives = 116/282 (41%), Gaps = 25/282 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G G V Y GT VA+K + + P+ + EI +++ H +I+ Sbjct 625 KIGQGASGGV----YTAYEIGTNVSVAIKQMNLEKQPK-KELIINEILVMKGSKHPNIVN 679 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 + +G+ L ++MEY+ GSL D + + Q+ ++ G+ +LH++ +H Sbjct 680 FIDSYVLKGD--LWVIMEYMEGGSLTDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLH 737 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RD+ + N+LL + +K+ DFG + +E R +W APE + ++ Sbjct 738 RDIKSDNILLSMEGDIKLTDFGFCAQI---NELNLKRTTMVGTPYWMAPEVVSRKEYGPK 794 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 D+WS G+ + E++ + T L IA +L P+ Sbjct 795 VDIWSLGIMIIEMI-EGEPPYLNETPLRALYLIATNGTP------------KLKEPENLS 841 Query 1142 CEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAP 1181 + + C E R + L+ + + E AP Sbjct 842 SSLKKFLDWCLCVEPEDRASATELLHDEYITEIAEANSSLAP 883 Score = 185 bits (470), Expect = 1e-46, Method: Composition-based stats. Identities = 60/300 (20%), Positives = 100/300 (33%), Gaps = 44/300 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L+++ + L +GQG VY + G Sbjct 607 LNEICSDGDPSTKYANLVKIGQGASGGVY------------------------TAYEIGT 642 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 + V +K ++ +M H ++ V + ++ EY+E G L Sbjct 643 NVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSL 702 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 + + V ++ S L +L +K ++H ++ NILL+ G I Sbjct 703 TDVVTH--CILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGD-------I 753 Query 756 KLSDPGVGLGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D G L R V W+APE + +D W G ++E+ +G Sbjct 754 KLTDFGFCAQINELNLKRTTMVGTPYWMAPEVVS--RKEYGPKVDIWSLGIMIIEMI-EG 810 Query 812 EAPLQSRSPSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 E P + +P + PE L CL EP R S +L D Sbjct 811 EPPYLNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELLHDEY 870 >sp|Q9FIL7|CRCK1_ARATH Calmodulin-binding receptor-like cytoplasmic kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CRCK1 PE=1 SV=1 Length=470 Score = 223 bits (568), Expect = 4e-62, Method: Composition-based stats. Identities = 74/312 (24%), Positives = 127/312 (41%), Gaps = 16/312 (5%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-C 936 P + + +GEG FG V D G +VA+K + + Sbjct 128 WHQGPVIFSFGELQRATANFSSVHQIGEGGFGTVFKGKLD-----DGTIVAIKRARKNNY 182 Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRH 993 G +K EI L + H +++K G E EK +V+EYV G+LR++L + Sbjct 183 GKSWLLEFKNEIYTLSKIEHMNLVKLYGFLEHGDEK--VIVVEYVANGNLREHLDGLRGN 240 Query 994 SIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 + +A+ L A + + YLH IHRD+ A N+L+ N K+ DFG A+ V E Sbjct 241 RLEMAERLEIAIDVAHALTYLHTYTDSPIIHRDIKASNILITNKLRAKVADFGFARLVSE 300 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFL 1109 + + P+ L+ ++ SDV+SFGV L E+LT + P K Sbjct 301 DLGATHISTQVKGSAGYVDPDYLRTFQLTDKSDVYSFGVLLVEILTGRRPIELKRPRKDR 360 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPD-KCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 + A ++ +++ + R + ++ L C + RP + + Sbjct 361 LTVKWALRRLKDDEAVLIMDPFLKRNRAAIEVAEKMLRLASECVTPTRATRPAMKGIAEK 420 Query 1169 LKTVHEKYQGQA 1180 L + + + Sbjct 421 LWAIRREMKETM 432 Score = 197 bits (500), Expect = 4e-53, Method: Composition-based stats. Identities = 64/332 (19%), Positives = 116/332 (35%), Gaps = 67/332 (20%) Query 579 LSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 SF + + + +G+G V++G+L Sbjct 135 FSFGELQRATANFSSVHQIGEGGFGTVFKGKLDDG------------------------- 169 Query 637 LRVVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 V +K ++ L F +S++ H +L ++G G E ++V EYV +G Sbjct 170 TIVAIKRARKNNYGKSWLLEFKNEIYTLSKIEHMNLVKLYGFLEHGDEKVIVVEYVANGN 229 Query 695 LDVWLRRERGH-VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEG 750 L L RG+ + MA ++ +A +A AL+YL + ++H ++ NIL+ A Sbjct 230 LREHLDGLRGNRLEMAERLEIAIDVAHALTYLHTYTDSPIIHRDIKASNILITNKLRA-- 287 Query 751 TSPFIKLSDPGVGLGALSR-------EERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 K++D G + ++ P+ L L+ D + FG Sbjct 288 -----KVADFGFARLVSEDLGATHISTQVKGSAGYVDPDYLRT--FQLTDKSDVYSFGVL 340 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP-----SCPQLA-------------TLT 845 L+EI R ++ RL + P L L Sbjct 341 LVEILTGRRPIELKRPRKDRLTVKWALRRLKDDEAVLIMDPFLKRNRAAIEVAEKMLRLA 400 Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 S+C+T RP+ + I L ++ + Sbjct 401 SECVTPTRATRPAMKGIAEKLWAIRREMKETM 432 >sp|Q54JG7|DST4_DICDI Serine/threonine-protein kinase dst4 OS=Dictyostelium discoideum OX=44689 GN=dst4 PE=3 SV=1 Length=485 Score = 223 bits (569), Expect = 4e-62, Method: Composition-based stats. Identities = 77/294 (26%), Positives = 125/294 (43%), Gaps = 33/294 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT-LYHEHIIK 961 +G+G FG V N E+VA+K L+ + + S K+EI IL+ + +I+K Sbjct 27 IGQGSFGVVCTC----INTVNNEVVAIKFLEMEG--EENSSLKKEITILKNTVRCPYIVK 80 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y GC E +L +VMEY GS+ D + ++ AQ+ QI EG+ YLH+ Sbjct 81 YHGCYIK--ENNLMIVMEYCDGGSILDIMQMCSITLTEAQIAAILYQIVEGLVYLHSNKI 138 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK----E 1075 +HRD+ A NVL++ K+ DFG++ + + +W +PE + Sbjct 139 LHRDIKAGNVLVNKLGQAKLADFGVSAILVNTGFKQKT---VVGSPYWMSPEVISPPKGS 195 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + +D+WS G+T E+ + PP L + + + L Sbjct 196 NGYDSKADIWSLGITAIEM-----AESKPPLFNLNPVKVI--------FVIPFRQAPTLE 242 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAPSVFSVC 1187 P E + C EA RP+ +L+ P +K E Q + C Sbjct 243 VPGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFIKKGKEHSQPTISEMVEQC 296 Score = 196 bits (498), Expect = 1e-52, Method: Composition-based stats. Identities = 58/325 (18%), Positives = 115/325 (35%), Gaps = 44/325 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 ++ L +GQG+ V V V + Sbjct 14 EEDPEQLFRVLEVIGQGSFGVVCTCINTVNNE------------------------VVAI 49 Query 642 KVLDPSHHDIALAFYETASLMSQ-VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L+ + + + + +++ V ++ HG ++ ++V EY + G + ++ Sbjct 50 KFLEMEGEENS-SLKKEITILKNTVRCPYIVKYHGCYIKENNLMIVMEYCDGGSILDIMQ 108 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + A + Q+ L YL + ++H ++ N+L+ +LG A KL+D Sbjct 109 MCSITLTEAQIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQA-------KLADF 161 Query 761 GVGL----GALSREERVERIPWLAPECL--PGGANSLSTAMDKWGFGATLLEICFDGEAP 814 GV ++ V W++PE + P G+N + D W G T +E+ + P Sbjct 162 GVSAILVNTGFKQKTVVGSPYWMSPEVISPPKGSNGYDSKADIWSLGITAIEMAES-KPP 220 Query 815 LQSRSPSEKEHFYQRQH----RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 L + +P + + +P P+ S CL E +RPS +L + Sbjct 221 LFNLNPVKVIFVIPFRQAPTLEVPGNWSPEFNDFISVCLNKEADKRPSAVDLLNHPFIKK 280 Query 871 PHNLADVLTVNPDSPASDPTVFHKR 895 + ++R Sbjct 281 GKEHSQPTISEMVEQCIPTMKEYRR 305 >sp|A0A2I0BVG8|CDPK1_PLAFO Calcium-dependent protein kinase 1 OS=Plasmodium falciparum (isolate NF54) OX=5843 GN=PDCK1 PE=1 SV=1 Length=524 Score = 224 bits (572), Expect = 4e-62, Method: Composition-based stats. Identities = 76/292 (26%), Positives = 117/292 (40%), Gaps = 47/292 (16%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--------------DCGPQHRS 942 K+R LG G +G+V L + GE A+K +K +C + Sbjct 56 YFKVRKLGSGAYGEVLLCREKHGH---GEK-AIKVIKKSQFDKMKYSITNKIECDDKIHE 111 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLL 1001 EI +L++L H +IIK ED+ K LV E+ G L + + RH Sbjct 112 EIYNEISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAA 169 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVR 1058 +QI G+ YLH + +HRD+ N+LL+N +KI DFGL+ + ++ Sbjct 170 NIMKQILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKL---- 225 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 D ++ APE L+ K+ DVWS GV LY LL G Sbjct 226 RDRLGTAYYIAPEVLR-KKYNEKCDVWSCGVILYILLCGYPPF---------------GG 269 Query 1119 MTVLRLTELLERG-ERLPRPD--KCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + +E+G D E L+K + + R T + + Sbjct 270 QNDQDIIKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALN 321 Score = 181 bits (458), Expect = 4e-47, Method: Composition-based stats. Identities = 66/382 (17%), Positives = 119/382 (31%), Gaps = 36/382 (9%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + ++ LG G V R + + + + + Sbjct 54 ESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNK---------IE 104 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 I Y SL+ + H ++ + V +VTE+ E G L + R Sbjct 105 CDDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQII-NRHKF 163 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + +Q+ S + YL N+VH ++ NILL + + IK+ D G+ Sbjct 164 DECDAANIMKQILSGICYLHKHNIVHRDIKPENILLEN----KHSLLNIKIVDFGLSSFF 219 Query 767 LSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 +R+ ++APE L + D W G L I G P ++ + Sbjct 220 SKDNKLRDRLGTAYYIAPEVLR---KKYNEKCDVWSCGVILY-ILLCGYPPFGGQNDQDI 275 Query 824 EHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 ++ + + L LTY+ +R + + L + N + Sbjct 276 IKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALNSKWIKKYANNINKS 335 Query 879 TVNPDSPASDPTVFHKRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC 936 A + K + L G L + + T K L + Sbjct 336 DQKTLCGALSNMRKFEGSQKLAQAAILFIGS----KLTTLEERKELTDIF---KKLDKNG 388 Query 937 GPQHRSGWKQE-IDILRTLYHE 957 Q E +ILR+ +E Sbjct 389 DGQLDKKELIEGYNILRSFKNE 410 >sp|P62343|CDPK1_PLAFK Calcium-dependent protein kinase 1 OS=Plasmodium falciparum (isolate K1 / Thailand) OX=5839 GN=CDPK1 PE=1 SV=2 Length=524 Score = 224 bits (572), Expect = 4e-62, Method: Composition-based stats. Identities = 76/292 (26%), Positives = 117/292 (40%), Gaps = 47/292 (16%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--------------DCGPQHRS 942 K+R LG G +G+V L + GE A+K +K +C + Sbjct 56 YFKVRKLGSGAYGEVLLCREKHGH---GEK-AIKVIKKSQFDKMKYSITNKIECDDKIHE 111 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLL 1001 EI +L++L H +IIK ED+ K LV E+ G L + + RH Sbjct 112 EIYNEISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAA 169 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVR 1058 +QI G+ YLH + +HRD+ N+LL+N +KI DFGL+ + ++ Sbjct 170 NIMKQILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKL---- 225 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 D ++ APE L+ K+ DVWS GV LY LL G Sbjct 226 RDRLGTAYYIAPEVLR-KKYNEKCDVWSCGVILYILLCGYPPF---------------GG 269 Query 1119 MTVLRLTELLERG-ERLPRPD--KCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + +E+G D E L+K + + R T + + Sbjct 270 QNDQDIIKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALN 321 Score = 181 bits (458), Expect = 4e-47, Method: Composition-based stats. Identities = 66/382 (17%), Positives = 119/382 (31%), Gaps = 36/382 (9%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + ++ LG G V R + + + + + Sbjct 54 ESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNK---------IE 104 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 I Y SL+ + H ++ + V +VTE+ E G L + R Sbjct 105 CDDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQII-NRHKF 163 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + +Q+ S + YL N+VH ++ NILL + + IK+ D G+ Sbjct 164 DECDAANIMKQILSGICYLHKHNIVHRDIKPENILLEN----KHSLLNIKIVDFGLSSFF 219 Query 767 LSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 +R+ ++APE L + D W G L I G P ++ + Sbjct 220 SKDNKLRDRLGTAYYIAPEVLR---KKYNEKCDVWSCGVILY-ILLCGYPPFGGQNDQDI 275 Query 824 EHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 ++ + + L LTY+ +R + + L + N + Sbjct 276 IKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALNSKWIKKYANNINKS 335 Query 879 TVNPDSPASDPTVFHKRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC 936 A + K + L G L + + T K L + Sbjct 336 DQKTLCGALSNMRKFEGSQKLAQAAILFIGS----KLTTLEERKELTDIF---KKLDKNG 388 Query 937 GPQHRSGWKQE-IDILRTLYHE 957 Q E +ILR+ +E Sbjct 389 DGQLDKKELIEGYNILRSFKNE 410 >sp|P62344|CDPK1_PLAF7 Calcium-dependent protein kinase 1 OS=Plasmodium falciparum (isolate 3D7) OX=36329 GN=CDPK1 PE=1 SV=2 Length=524 Score = 224 bits (572), Expect = 4e-62, Method: Composition-based stats. Identities = 76/292 (26%), Positives = 117/292 (40%), Gaps = 47/292 (16%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--------------DCGPQHRS 942 K+R LG G +G+V L + GE A+K +K +C + Sbjct 56 YFKVRKLGSGAYGEVLLCREKHGH---GEK-AIKVIKKSQFDKMKYSITNKIECDDKIHE 111 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLL 1001 EI +L++L H +IIK ED+ K LV E+ G L + + RH Sbjct 112 EIYNEISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAA 169 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVR 1058 +QI G+ YLH + +HRD+ N+LL+N +KI DFGL+ + ++ Sbjct 170 NIMKQILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKL---- 225 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 D ++ APE L+ K+ DVWS GV LY LL G Sbjct 226 RDRLGTAYYIAPEVLR-KKYNEKCDVWSCGVILYILLCGYPPF---------------GG 269 Query 1119 MTVLRLTELLERG-ERLPRPD--KCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + +E+G D E L+K + + R T + + Sbjct 270 QNDQDIIKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALN 321 Score = 181 bits (458), Expect = 4e-47, Method: Composition-based stats. Identities = 66/382 (17%), Positives = 119/382 (31%), Gaps = 36/382 (9%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + ++ LG G V R + + + + + Sbjct 54 ESYFKVRKLGSGAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNK---------IE 104 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 I Y SL+ + H ++ + V +VTE+ E G L + R Sbjct 105 CDDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQII-NRHKF 163 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + +Q+ S + YL N+VH ++ NILL + + IK+ D G+ Sbjct 164 DECDAANIMKQILSGICYLHKHNIVHRDIKPENILLEN----KHSLLNIKIVDFGLSSFF 219 Query 767 LSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 +R+ ++APE L + D W G L I G P ++ + Sbjct 220 SKDNKLRDRLGTAYYIAPEVLR---KKYNEKCDVWSCGVILY-ILLCGYPPFGGQNDQDI 275 Query 824 EHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 ++ + + L LTY+ +R + + L + N + Sbjct 276 IKKVEKGKYYFDFNDWKNISEEAKELIKLMLTYDYNKRITAKEALNSKWIKKYANNINKS 335 Query 879 TVNPDSPASDPTVFHKRYLKKIRD--LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC 936 A + K + L G L + + T K L + Sbjct 336 DQKTLCGALSNMRKFEGSQKLAQAAILFIGS----KLTTLEERKELTDIF---KKLDKNG 388 Query 937 GPQHRSGWKQE-IDILRTLYHE 957 Q E +ILR+ +E Sbjct 389 DGQLDKKELIEGYNILRSFKNE 410 >sp|P41892|CDC7_SCHPO Cell division control protein 7 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=cdc7 PE=1 SV=1 Length=1062 Score = 234 bits (598), Expect = 4e-62, Method: Composition-based stats. Identities = 79/281 (28%), Positives = 119/281 (42%), Gaps = 28/281 (10%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQE 947 + LG+G FG V Y N GE VAVK +K + S K E Sbjct 1 MHNIQASSITLGDCLGKGAFGAV----YRGLNIKNGETVAVKKVKLSKMLKSDLSVIKME 56 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQ 1006 ID+L+ L H +I+KY+G Q SL +++EY GSLR I + L+ Q Sbjct 57 IDLLKNLDHPNIVKYRGSY--QTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQ 114 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 + +G+ YLH Q IHRD+ N+L D +K+ DFG+A + ++ + Sbjct 115 VLQGLLYLHNQGVIHRDIKGANILTTKDGTIKLADFGVATKINALEDH-----SVVGSPY 169 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE ++ ASD+WS G T+ ELL +PP L+ + Sbjct 170 WMAPEVIELVGATTASDIWSVGCTVIELL-----DGNPPYYDLDPTSALFRMV------- 217 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + E P P + C++ + + R L+ Sbjct 218 ---KDEHPPLPSNISSAAKSFLMQCFQKDPNLRIKTRKLLK 255 Score = 207 bits (527), Expect = 2e-53, Method: Composition-based stats. Identities = 66/297 (22%), Positives = 104/297 (35%), Gaps = 41/297 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 H + IT LG+G VY G G V + Sbjct 2 HNIQASSITLGDCLGKGAFGAVYRGLNIKNGE------------------------TVAV 37 Query 642 KVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 K + S + L+ + H ++ G ++ EY E+G L + Sbjct 38 KKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRGSYQTNDSLCIILEYCENGSLRS-I 96 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + G +P + Q+ L YL N+ ++H ++ G NIL + G IKL+D Sbjct 97 CKNFGKIPENLVALYTFQVLQGLLYLHNQGVIHRDIKGANILTTKDG-------TIKLAD 149 Query 760 PGVG--LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 GV + AL V W+APE + +TA D W G T++E+ DG P Sbjct 150 FGVATKINALEDHSVVGSPYWMAPEVIELVGA--TTASDIWSVGCTVIELL-DGNPPYYD 206 Query 818 RSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 P+ + LP + QC +P R R +L+ + Sbjct 207 LDPTSALFRMVKDEHPPLPSNISSAAKSFLMQCFQKDPNLRIKTRKLLKHPWVIMNQ 263 >sp|Q04982|BRAF_CHICK Serine/threonine-protein kinase B-raf OS=Gallus gallus OX=9031 GN=BRAF PE=1 SV=2 Length=766 Score = 230 bits (587), Expect = 4e-62, Method: Composition-based stats. Identities = 76/306 (25%), Positives = 130/306 (42%), Gaps = 31/306 (10%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 + + +SD + + +G G FG V + VAVK L Sbjct 435 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-------DVAVKMLNV 487 Query 935 DC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991 PQ +K E+ +LR H +I+ + G + L +V ++ SL +L Sbjct 488 TAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY---STKPQLAIVTQWCEGSSLYHHLHII 544 Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 + +L+ A+Q +GM YLHA+ IHRDL + N+ L D VKIGDFGLA Sbjct 545 ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRW 604 Query 1052 HEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQ--SPPT 1106 ++ E + W APE ++ + + + SDV++FG+ LYEL+T + Sbjct 605 SGSHQF-EQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRD 663 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + + ++G + ++ CP + LM C + + RP F ++ Sbjct 664 QIIFMVGRGYLSPDLSKVR------------SNCPKAMKRLMAECLKKKRDERPLFPQIL 711 Query 1167 PILKTV 1172 ++ + Sbjct 712 ASIELL 717 Score = 225 bits (573), Expect = 3e-60, Method: Composition-based stats. Identities = 71/378 (19%), Positives = 130/378 (34%), Gaps = 57/378 (15%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSF-HRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 P P R +TL S + +IT +G G+ VY+G+ + Sbjct 420 PGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD 479 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSHTH 669 V +K+L+ + AF ++ + H + Sbjct 480 ---------------------------VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVN 512 Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729 + G + P+ +VT++ E L L M + +A+Q A + YL K+ Sbjct 513 ILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKS 571 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPEC 783 ++H ++ NI L +K+ D G+ G+ E+ I W+APE Sbjct 572 IIHRDLKSNNIFLHE-------DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEV 624 Query 784 LPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP------ 836 + N S D + FG L E+ G+ P + + ++ F + L Sbjct 625 IRMQDKNPYSFQSDVYAFGIVLYELM-TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRS 683 Query 837 SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL----TRLQPHNLADVLTVNPDSPASDPTV 891 +CP+ + L ++CL + +RP F IL + L + + + Sbjct 684 NCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDF 743 Query 892 FHKRYLKKIRDLGEGHFG 909 + G +G Sbjct 744 SLYACASPKTPIQAGGYG 761 >sp|C0LGD9|Y1756_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g07560 OS=Arabidopsis thaliana OX=3702 GN=At1g07560 PE=1 SV=1 Length=871 Score = 232 bits (592), Expect = 4e-62, Method: Composition-based stats. Identities = 68/273 (25%), Positives = 118/273 (43%), Gaps = 14/273 (5%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V + T E VAVK L Q +K E+++L +YH +++ Sbjct 576 LGKGGFGMVYHGYINGT-----EEVAVKLLSP-SSAQGYKEFKTEVELLLRVYHTNLVSL 629 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLH---AQH 1018 G C+++ L L+ +Y+ G L+ + SI L A G+ YLH Sbjct 630 VGYCDEKDH--LALIYQYMVNGDLKKHFSGSSIISWVDRLNIAVDAASGLEYLHIGCKPL 687 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRD+ + N+LLD+ K+ DFGL+++ P G E + V + E + + Sbjct 688 IVHRDVKSSNILLDDQLQAKLADFGLSRSFPIGDESH-VSTLVAGTFGYLDHEYYQTNRL 746 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SDV+SFGV L E++T+ + + +T ++ +++ + Sbjct 747 SEKSDVYSFGVVLLEIITNKPVIDH-NRDMPHIAEWVKLMLTRGDISNIMDPKLQGVYDS 805 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + L C + RP +++ LK Sbjct 806 GSAWKALELAMTCVNPSSLKRPNMSHVVHELKE 838 Score = 200 bits (509), Expect = 1e-51, Method: Composition-based stats. Identities = 63/312 (20%), Positives = 101/312 (32%), Gaps = 59/312 (19%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 + ++ V LG+G VY G + Sbjct 558 KRYTYAEVLAMTKKFERVLGKGGFGMVYHGYINGTE------------------------ 593 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K+L PS F L+ +V HT+L + G C ++ +Y+ +G L Sbjct 594 -EVAVKLLSPSSAQGYKEFKTEVELLLRVYHTNLVSLVGYCDEKDHLALIYQYMVNGDLK 652 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSP 753 + ++ +A AS L YL +VH +V NILL A Sbjct 653 KH-FSGSSIISWVDRLNIAVDAASGLEYLHIGCKPLIVHRDVKSSNILLDDQLQA----- 706 Query 754 FIKLSDPGVGLG-ALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 KL+D G+ + E V +L E N LS D + FG LLEI Sbjct 707 --KLADFGLSRSFPIGDESHVSTLVAGTFGYLDHEYYQT--NRLSEKSDVYSFGVVLLEI 762 Query 808 CFDGEAPLQSRSP---SEKEHFYQRQHRLPEPSCPQL------------ATLTSQCLTYE 852 + +R +E + + P+L L C+ Sbjct 763 ITNKPVIDHNRDMPHIAEWVKLMLTRGDISNIMDPKLQGVYDSGSAWKALELAMTCVNPS 822 Query 853 PTQRPSFRTILR 864 +RP+ ++ Sbjct 823 SLKRPNMSHVVH 834 >sp|O80939|LRK41_ARATH L-type lectin-domain containing receptor kinase IV.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK41 PE=2 SV=1 Length=675 Score = 228 bits (582), Expect = 4e-62, Method: Composition-based stats. Identities = 73/276 (26%), Positives = 116/276 (42%), Gaps = 17/276 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V Y GT +AVK + + Q + EI + + H +++ Sbjct 353 LGTGGFGSV----YKGVMPGTKLEIAVKRVSHE-SRQGMKEFVAEIVSIGRMSHRNLVPL 407 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018 G C +GE L LV +Y+P GSL YL P ++ Q + + G+ YLH + Sbjct 408 LGYCRRRGE--LLLVYDYMPNGSLDKYLYNTPEVTLNWKQRIKVILGVASGLFYLHEEWE 465 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ A NVLLD + ++GDFGLA+ G + + + APE + Sbjct 466 QVVIHRDVKASNVLLDGELNGRLGDFGLARLYDHGSDPQTTH--VVGTLGYLAPEHTRTG 523 Query 1077 KFYYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + A+DV++FG L E+ Q + L+ G + + Sbjct 524 RATMATDVFAFGAFLLEVACGRRPIEFQQETDETFLLVDWVFGLWNKGDILAAKDPNMGS 583 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +K V L C ++ RP+ ++ L+ Sbjct 584 ECDEKEVEMVLKLGLLCSHSDPRARPSMRQVLHYLR 619 Score = 204 bits (519), Expect = 8e-54, Method: Composition-based stats. Identities = 63/308 (20%), Positives = 104/308 (34%), Gaps = 60/308 (19%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 K + LG G +VY+G + G +L + +K + Sbjct 343 ATKGFKEKGLLGTGGFGSVYKGVM------------------------PGTKLEIAVKRV 378 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ER 703 F + ++SH +L + G C R E ++V +Y+ +G LD +L Sbjct 379 SHESRQGMKEFVAEIVSIGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNTPE 438 Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + ++ V +AS L YL + ++H +V N+LL +L D Sbjct 439 VTLNWKQRIKVILGVASGLFYLHEEWEQVVIHRDVKASNVLLD-------GELNGRLGDF 491 Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ V + +LAPE G +++T D + FGA LLE+ Sbjct 492 GLARLYDHGSDPQTTHVVGTLGYLAPEHTRTGRATMAT--DVFAFGAFLLEVACGRRPIE 549 Query 816 QSRSPSEKEHFYQRQHRLP------------------EPSCPQLATLTSQCLTYEPTQRP 857 + E L E + L C +P RP Sbjct 550 FQQETDETFLLVDWVFGLWNKGDILAAKDPNMGSECDEKEVEMVLKLGLLCSHSDPRARP 609 Query 858 SFRTILRD 865 S R +L Sbjct 610 SMRQVLHY 617 >sp|Q9CAD5|YODA_ARATH Mitogen-activated protein kinase kinase kinase YODA OS=Arabidopsis thaliana OX=3702 GN=YDA PE=1 SV=1 Length=883 Score = 232 bits (592), Expect = 4e-62, Method: Composition-based stats. Identities = 88/312 (28%), Positives = 134/312 (43%), Gaps = 30/312 (10%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 I ++ A +V ++ TV KK R LG G FG V L N Sbjct 365 ISNTCPFSPTYSAATSPSVPRSPARAEATVSPGSRWKKGRLLGMGSFGHVYLGF----NS 420 Query 922 GTGEMVAVKALKA-DCGPQHRSGWKQ---EIDILRTLYHEHIIKYKGCCEDQGEKSLQLV 977 +GEM A+K + P+ R +Q EI +L L H++I++Y G + + L + Sbjct 421 ESGEMCAMKEVTLCSDDPKSRESAQQLGQEISVLSRLRHQNIVQYYGS--ETVDDKLYIY 478 Query 978 MEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036 +EYV GS+ L + G + + QQI G+AYLHA++ +HRD+ N+L+D Sbjct 479 LEYVSGGSIYKLLQEYGQFGENAIRNYTQQILSGLAYLHAKNTVHRDIKGANILVDPHGR 538 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELL 1095 VK+ DFG+AK + +W APE +K A D+WS G T+ E+ Sbjct 539 VKVADFGMAKHI----TAQSGPLSFKGSPYWMAPEVIKNSNGSNLAVDIWSLGCTVLEMA 594 Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155 T PP E V + ++ E PD E ++ C + Sbjct 595 T-----TKPPWSQYE---------GVPAMFKIGNSKELPDIPDHLSEEGKDFVRKCLQRN 640 Query 1156 ASFRPTFENLIP 1167 + RPT L+ Sbjct 641 PANRPTAAQLLD 652 Score = 191 bits (486), Expect = 1e-48, Method: Composition-based stats. Identities = 74/349 (21%), Positives = 117/349 (34%), Gaps = 40/349 (11%) Query 539 RAGDDCFSLRRCCLPQPGETSNLIIMR---GARASPRTLNLSQLSFHRVDQ-KEITQLSH 594 R D+ R LP P SN A SP + V + Sbjct 347 RLDDNRQQSHRLPLP-PLLISNTCPFSPTYSAATSPSVPRSPARAEATVSPGSRWKKGRL 405 Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LG G+ +VY G G + V L DP + A Sbjct 406 LGMGSFGHVYLGFNSESGEMCAMK-------------------EVTLCSDDPKSRESAQQ 446 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVV 714 + S++S++ H ++ +G + + EYV G + L+ E G Sbjct 447 LGQEISVLSRLRHQNIVQYYGSETVDDKLYIYLEYVSGGSIYKLLQ-EYGQFGENAIRNY 505 Query 715 AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---E 771 QQ+ S L+YL KN VH ++ G NIL+ G +K++D G+ ++ Sbjct 506 TQQILSGLAYLHAKNTVHRDIKGANILVDPHGR-------VKVADFGMAKHITAQSGPLS 558 Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 W+APE + S + A+D W G T+LE+ + P Sbjct 559 FKGSPYWMAPEVIKNSNGS-NLAVDIWSLGCTVLEMATT-KPPWSQYEGVPAMFKIGNSK 616 Query 832 RL---PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 L P+ + +CL P RP+ +L + Sbjct 617 ELPDIPDHLSEEGKDFVRKCLQRNPANRPTAAQLLDHAFVRNVMPMERP 665 >sp|Q8CIP4|MARK4_MOUSE MAP/microtubule affinity-regulating kinase 4 OS=Mus musculus OX=10090 GN=Mark4 PE=1 SV=1 Length=752 Score = 230 bits (586), Expect = 4e-62, Method: Composition-based stats. Identities = 77/292 (26%), Positives = 126/292 (43%), Gaps = 30/292 (10%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEID 949 H + +R +G+G+F KV L + TG VA+K + K P +E+ Sbjct 53 QPHVGNYRLLRTIGKGNFAKVKL----ARHILTGREVAIKIIDKTQLNPSSLQKLFREVR 108 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQIC 1008 I++ L H +I+K E EK+L LVMEY G + DYL H + + +QI Sbjct 109 IMKGLNHPNIVKLFEVIE--TEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIV 166 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 + Y H ++ +HRDL A N+LLD + +KI DFG + G + + + Sbjct 167 SAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKL----DTFCGSPPYA 222 Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + K+ D+WS GV LY L++ + L E Sbjct 223 APELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFD---------------GHNLKELRER 267 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 + RG + P + +++ + R T E ++ K ++ Y+G+ Sbjct 268 VLRG-KYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKD-KWINIGYEGE 317 Score = 188 bits (477), Expect = 4e-48, Method: Composition-based stats. Identities = 53/286 (19%), Positives = 96/286 (34%), Gaps = 40/286 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 L +G+G V R + G V +K++D + Sbjct 58 NYRLLRTIGKGNFAKVKLARHILTGR------------------------EVAIKIIDKT 93 Query 648 HHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + + + +M ++H ++ + V +V EY G + +L G Sbjct 94 QLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSH-GR 152 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763 + +Q+ SA+ Y KN+VH ++ N+LL IK++D G Sbjct 153 MKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD-------AEANIKIADFGFSNE 205 Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + P+ APE G +D W G L + G P + E Sbjct 206 FTLGSKLDTFCGSPPYAAPELFQGKKYD-GPEVDIWSLGVILYTLVS-GSLPFDGHNLKE 263 Query 823 KEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 R +R+P ++ + L P +R + I++D Sbjct 264 LRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKW 309 >sp|Q96L34|MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 OS=Homo sapiens OX=9606 GN=MARK4 PE=1 SV=1 Length=752 Score = 230 bits (586), Expect = 4e-62, Method: Composition-based stats. Identities = 77/292 (26%), Positives = 126/292 (43%), Gaps = 30/292 (10%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEID 949 H + +R +G+G+F KV L + TG VA+K + K P +E+ Sbjct 53 QPHVGNYRLLRTIGKGNFAKVKL----ARHILTGREVAIKIIDKTQLNPSSLQKLFREVR 108 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQIC 1008 I++ L H +I+K E EK+L LVMEY G + DYL H + + +QI Sbjct 109 IMKGLNHPNIVKLFEVIE--TEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIV 166 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 + Y H ++ +HRDL A N+LLD + +KI DFG + G + + + Sbjct 167 SAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKL----DTFCGSPPYA 222 Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + K+ D+WS GV LY L++ + L E Sbjct 223 APELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFD---------------GHNLKELRER 267 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 + RG + P + +++ + R T E ++ K ++ Y+G+ Sbjct 268 VLRG-KYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKD-KWINIGYEGE 317 Score = 188 bits (477), Expect = 4e-48, Method: Composition-based stats. Identities = 53/286 (19%), Positives = 96/286 (34%), Gaps = 40/286 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 L +G+G V R + G V +K++D + Sbjct 58 NYRLLRTIGKGNFAKVKLARHILTGR------------------------EVAIKIIDKT 93 Query 648 HHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + + + +M ++H ++ + V +V EY G + +L G Sbjct 94 QLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSH-GR 152 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763 + +Q+ SA+ Y KN+VH ++ N+LL IK++D G Sbjct 153 MKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD-------AEANIKIADFGFSNE 205 Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + P+ APE G +D W G L + G P + E Sbjct 206 FTLGSKLDTFCGSPPYAAPELFQGKKYD-GPEVDIWSLGVILYTLVS-GSLPFDGHNLKE 263 Query 823 KEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 R +R+P ++ + L P +R + I++D Sbjct 264 LRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKW 309 >sp|C0LGF5|RGI5_ARATH LRR receptor-like serine/threonine-protein kinase RGI5 OS=Arabidopsis thaliana OX=3702 GN=RGI5 PE=1 SV=2 Length=1072 Score = 234 bits (598), Expect = 4e-62, Method: Composition-based stats. Identities = 73/313 (23%), Positives = 120/313 (38%), Gaps = 19/313 (6%) Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932 + + T P L +G+G G V G++VAVK L Sbjct 748 DFSYPWTFIPFQKLGITVNNIVTSLTDENVIGKGCSGIVYKA-----EIPNGDIVAVKKL 802 Query 933 -----KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 + G + EI IL + H +I+K G C ++ K L+ Y P G+L+ Sbjct 803 WKTKDNNEEGESTIDSFAAEIQILGNIRHRNIVKLLGYCSNKSVK--LLLYNYFPNGNLQ 860 Query 988 DYLP-RHSIGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFG 1043 L ++ A +G+AYLH +HRD+ N+LLD+ + DFG Sbjct 861 QLLQGNRNLDWETRYKIAIGAAQGLAYLHHDCVPAILHRDVKCNNILLDSKYEAILADFG 920 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 LAK + Y+ + APE SDV+S+GV L E+L+ + + Sbjct 921 LAKLMMNSPNYHNAMSRVAGSYGYIAPEYGYTMNITEKSDVYSYGVVLLEILSGRSAVEP 980 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH---LMKNCWETEASFRP 1160 L ++ + +M + + PD+ E+ + C RP Sbjct 981 QIGDGLHIVEWVKKKMGTFEPALSVLDVKLQGLPDQIVQEMLQTLGIAMFCVNPSPVERP 1040 Query 1161 TFENLIPILKTVH 1173 T + ++ +L V Sbjct 1041 TMKEVVTLLMEVK 1053 Score = 178 bits (452), Expect = 3e-44, Method: Composition-based stats. Identities = 52/318 (16%), Positives = 106/318 (33%), Gaps = 70/318 (22%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL---- 644 +T + +G+G VY+ + V +K L Sbjct 772 LTDENVIGKGCSGIVYKAEIPNGDI-------------------------VAVKKLWKTK 806 Query 645 --DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 + +F ++ + H ++ + G C +++ Y +G L L+ Sbjct 807 DNNEEGESTIDSFAAEIQILGNIRHRNIVKLLGYCSNKSVKLLLYNYFPNGNLQQLLQGN 866 Query 703 RGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R ++ + +A A L+YL + ++H +V NILL A L+D Sbjct 867 R-NLDWETRYKIAIGAAQGLAYLHHDCVPAILHRDVKCNNILLDSKYEAI-------LAD 918 Query 760 PGVGLGALSREER-------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 G+ ++ ++APE G +++ D + +G LLEI Sbjct 919 FGLAKLMMNSPNYHNAMSRVAGSYGYIAPEY--GYTMNITEKSDVYSYGVVLLEILSGRS 976 Query 813 A--PLQSRSPSEKEHFYQRQHR--------------LPEPSCPQLAT---LTSQCLTYEP 853 A P E ++ LP+ ++ + C+ P Sbjct 977 AVEPQIGDGLHIVEWVKKKMGTFEPALSVLDVKLQGLPDQIVQEMLQTLGIAMFCVNPSP 1036 Query 854 TQRPSFRTILRDLTRLQP 871 +RP+ + ++ L ++ Sbjct 1037 VERPTMKEVVTLLMEVKC 1054 >sp|Q6PWX2|HOG1_BEABA Mitogen-activated protein kinase HOG1 OS=Beauveria bassiana OX=176275 GN=HOG1 PE=3 SV=1 Length=358 Score = 219 bits (558), Expect = 4e-62, Method: Composition-based stats. Identities = 67/284 (24%), Positives = 108/284 (38%), Gaps = 29/284 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VAVK + K P +E+ +L+ L HE++ Sbjct 24 QPVGMGAFGLVC----SARDQLTNQNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENV 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLDGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L + ER P + LM+ + R T + Sbjct 252 SLPKRERQPLRNKFRNADDSAIDLMERMLVFDPKKRITAAEALS 295 Score = 131 bits (330), Expect = 9e-32, Method: Composition-based stats. Identities = 38/231 (16%), Positives = 75/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E D + M + RD+ V +K ++ P +A Y Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAVKKIMKPFSTPVLAKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ DG+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-DGKPLFPGKDHVNQFSI 225 >sp|Q5XIT0|CDKL2_RAT Cyclin-dependent kinase-like 2 OS=Rattus norvegicus OX=10116 GN=Cdkl2 PE=2 SV=1 Length=507 Score = 224 bits (571), Expect = 4e-62, Method: Composition-based stats. Identities = 74/285 (26%), Positives = 122/285 (43%), Gaps = 29/285 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG +G V N +G +VA+K L++D + +EI +L+ L HE+++ Sbjct 10 VGEGSYGMVM----KCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 C + +K LV E+V L D L + + + + QI G+ + H+ + I Sbjct 66 LLEVC--KKKKRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFCHSHNII 123 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFY 1079 HRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L K+ Sbjct 124 HRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVKYG 180 Query 1080 YASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 A D+W+ G + E+L +S + +G + L + G RL Sbjct 181 KAVDIWAIGCLVIEMLMGQPLFPGESDIDQLHHIMTCLGNLIPRHQELFYKNPVFAGVRL 240 Query 1135 P------------RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P R K P V L K C + RP +L+ Sbjct 241 PEIKDIEAEPLESRYPKLPEVVISLAKKCLHIDPDKRPLCADLLH 285 Score = 163 bits (412), Expect = 3e-41, Method: Composition-based stats. Identities = 63/407 (15%), Positives = 122/407 (30%), Gaps = 85/407 (21%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-L 644 ++ L +G+G+ V + R + G V +K L Sbjct 1 MEKYENLGLVGEGSYGMVMKCRNKDSGR------------------------IVAIKKFL 36 Query 645 DPSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + + L+ Q+ H +L + VC + +V E+V+H LD L+ Sbjct 37 ESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDD-LKLFP 95 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + Q+ + + + + N++H ++ NIL+++ G+ +KL D G Sbjct 96 NGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFA 148 Query 764 LGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + + V + APE L G A+D W G ++E+ Sbjct 149 RTLAAPGEVYTDYVATRWYRAPELLV-GDVKYGKAVDIWAIGCLVIEMLMGQPLFPGESD 207 Query 820 PSEKEHFY-------------------QRQHRLPEPS--------------CPQLATLTS 846 + H RLPE + +L Sbjct 208 IDQLHHIMTCLGNLIPRHQELFYKNPVFAGVRLPEIKDIEAEPLESRYPKLPEVVISLAK 267 Query 847 QCLTYEPTQRP-SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 +CL +P +RP + D ++ + + + + + Sbjct 268 KCLHIDPDKRPLCADLLHHDFFQMDGFAERFSQELQLKIEKDARNNSLPKKFQIRKKEKD 327 Query 906 GHFGK------VSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 G+ V DP + K LK ++ Sbjct 328 DALGEERKTLVVQDTNADPKTKDS------KVLKVKGSKIDVEKTEK 368 >sp|P93749|Y2197_ARATH Probable protein kinase At2g41970 OS=Arabidopsis thaliana OX=3702 GN=At2g41970 PE=2 SV=1 Length=365 Score = 219 bits (559), Expect = 5e-62, Method: Composition-based stats. Identities = 69/284 (24%), Positives = 123/284 (43%), Gaps = 23/284 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG +G+V + GE VA+K L A + S + ++ ++ L H+H ++ Sbjct 79 IGEGSYGRVFCGKFK------GEAVAIKKLDASSSEEPDSDFTSQLSVVSRLKHDHFVEL 132 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----------IGLAQLLLFAQQICEGMA 1012 G C + + L+ ++ GSL D L + Q + A +G+ Sbjct 133 LGYCLEANNR--ILIYQFATKGSLHDVLHGRKGVQGAEPGPVLNWNQRVKIAYGAAKGLE 190 Query 1013 YLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 +LH + +HRD+ + NVLL +D + K+ DF L A + ++A Sbjct 191 FLHEKVQPPIVHRDVRSSNVLLFDDFVAKMADFNLTNASSDTAARLH-STRVLGTFGYHA 249 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE + SDV+SFGV L ELLT + P L+ A +++ ++ + + Sbjct 250 PEYAMTGQITQKSDVYSFGVVLLELLTGRKPVDHTMPKGQQSLVTWATPRLSEDKVKQCI 309 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + P K ++ + C + EA FRP ++ L+ + Sbjct 310 DPKLNNDFPPKAVAKLAAVAALCVQYEADFRPNMTIVVKALQPL 353 Score = 182 bits (461), Expect = 5e-49, Method: Composition-based stats. Identities = 52/290 (18%), Positives = 100/290 (34%), Gaps = 55/290 (19%) Query 566 GARASPRTLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 GA A + + ++ +++ + +G+G+ V+ G+ + E Sbjct 48 GAPAKVLPIEIPSVALDELNRMAGNFGNKALIGEGSYGRVFCGKFKGE------------ 95 Query 624 EDPLVPGRDRGQELRVVLKVLD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 V +K LD S + F S++S++ H H + G C+ Sbjct 96 --------------AVAIKKLDASSSEEPDSDFTSQLSVVSRLKHDHFVELLGYCLEANN 141 Query 683 NIMVTEYVEHGPLDVWLRRERG--------HVPMAWKMVVAQQLASALSYLENK---NLV 731 I++ ++ G L L +G + ++ +A A L +L K +V Sbjct 142 RILIYQFATKGSLHDVLHGRKGVQGAEPGPVLNWNQRVKIAYGAAKGLEFLHEKVQPPIV 201 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGALSREERVERIPWLAPECLP 785 H +V N+LL K++D + L + + APE Sbjct 202 HRDVRSSNVLL-------FDDFVAKMADFNLTNASSDTAARLHSTRVLGTFGYHAPEYAM 254 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 G ++ D + FG LLE+ + + ++ RL E Sbjct 255 TG--QITQKSDVYSFGVVLLELLTGRKPVDHTMPKGQQSLVTWATPRLSE 302 >sp|Q9JI10|STK3_MOUSE Serine/threonine-protein kinase 3 OS=Mus musculus OX=10090 GN=Stk3 PE=1 SV=1 Length=497 Score = 224 bits (570), Expect = 5e-62, Method: Composition-based stats. Identities = 64/268 (24%), Positives = 110/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V + + +G++VA+K + + Q +EI I++ +++K Sbjct 32 KLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQ---EIIKEISIMQQCDSPYVVK 84 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ + +G+ YLH Sbjct 85 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRK 142 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 143 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 199 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 200 CVADIWSLGITSIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 246 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 + +K C R T L+ Sbjct 247 WSDDFTDFVKKCLVKSPEQRATATQLLQ 274 Score = 199 bits (505), Expect = 2e-53, Method: Composition-based stats. Identities = 56/307 (18%), Positives = 99/307 (32%), Gaps = 44/307 (14%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 + + LS+ S + ++ L LG+G+ +V++ + G Sbjct 7 SKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQ--------------- 51 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 V +K + + S+M Q ++ +G + + +V E Sbjct 52 ---------VVAIKQVPVESD--LQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVME 100 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 Y G + +R + + + L YL +H ++ NILL G Sbjct 101 YCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-- 158 Query 749 EGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 KL+D GV R + W+APE + + D W G T Sbjct 159 -----HAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITS 211 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 +E+ +G+ P P R PE +CL P QR + Sbjct 212 IEMA-EGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATAT 270 Query 861 TILRDLT 867 +L+ Sbjct 271 QLLQHPF 277 >sp|O88643|PAK1_MOUSE Serine/threonine-protein kinase PAK 1 OS=Mus musculus OX=10090 GN=Pak1 PE=1 SV=1 Length=545 Score = 225 bits (573), Expect = 5e-62, Method: Composition-based stats. Identities = 72/370 (19%), Positives = 132/370 (36%), Gaps = 25/370 (7%) Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 P+ + P + Y R P P P + + ++ + R+ + + Sbjct 187 PPVIAPRPEHTKSVYTRSVIEPLPVTPT-RDVATSPISPTENNTTPPDALTRNTEKQKKK 245 Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932 + + K+ +G+G G V Y + TG+ VA+K + Sbjct 246 PKMSDEEILEKLRSIVSVGDPKKKYTPFEKIGQGASGTV----YTAMDVATGQEVAIKQM 301 Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992 P+ + EI ++R + +I+ Y E L +VMEY+ GSL D + Sbjct 302 NLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTE 358 Query 993 HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 + Q+ ++ + + +LH+ IHRD+ + N+LL D VK+ DFG + Sbjct 359 TCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITP-- 416 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 R +W APE + + D+WS G+ E++ PP + Sbjct 417 -EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMI-----EGEPPYLNENPL 470 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP-ILKT 1171 T L P+K ++ C E + R + + L+ Sbjct 471 RALYLIATNGT--------PELQNPEKLSAIFRDFLQCCLEMDVEKRGSAKELLQHQFLK 522 Query 1172 VHEKYQGQAP 1181 + + P Sbjct 523 IAKPLSSLTP 532 Score = 179 bits (455), Expect = 2e-46, Method: Composition-based stats. Identities = 54/291 (19%), Positives = 94/291 (32%), Gaps = 44/291 (15%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +K+ T +GQG VY D V +K + Sbjct 266 PKKKYTPFEKIGQGASGTVY------------------------TAMDVATGQEVAIKQM 301 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + +M + + ++ + G E +V EY+ G L + Sbjct 302 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 359 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + V ++ AL +L + ++H ++ NILL G +KL+D G Sbjct 360 CMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 412 Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 R V W+APE + A +D W G +E+ +GE P + +P Sbjct 413 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMI-EGEPPYLNENP 469 Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + PE CL + +R S + +L+ Sbjct 470 LRALYLIATNGTPELQNPEKLSAIFRDFLQCCLEMDVEKRGSAKELLQHQF 520 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens OX=9606 GN=BRAF PE=1 SV=4 Length=766 Score = 230 bits (586), Expect = 5e-62, Method: Composition-based stats. Identities = 76/306 (25%), Positives = 130/306 (42%), Gaps = 31/306 (10%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 + + +SD + + +G G FG V + VAVK L Sbjct 435 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-------DVAVKMLNV 487 Query 935 DC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991 PQ +K E+ +LR H +I+ + G + L +V ++ SL +L Sbjct 488 TAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY---STKPQLAIVTQWCEGSSLYHHLHII 544 Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 + +L+ A+Q +GM YLHA+ IHRDL + N+ L D VKIGDFGLA Sbjct 545 ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRW 604 Query 1052 HEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQ--SPPT 1106 ++ E + W APE ++ + + + SDV++FG+ LYEL+T + Sbjct 605 SGSHQF-EQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRD 663 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + + ++G + ++ CP + LM C + + RP F ++ Sbjct 664 QIIFMVGRGYLSPDLSKVR------------SNCPKAMKRLMAECLKKKRDERPLFPQIL 711 Query 1167 PILKTV 1172 ++ + Sbjct 712 ASIELL 717 Score = 224 bits (572), Expect = 4e-60, Method: Composition-based stats. Identities = 71/378 (19%), Positives = 130/378 (34%), Gaps = 57/378 (15%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSF-HRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 P P R +TL S + +IT +G G+ VY+G+ + Sbjct 420 PGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD 479 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSHTH 669 V +K+L+ + AF ++ + H + Sbjct 480 ---------------------------VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVN 512 Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729 + G + P+ +VT++ E L L M + +A+Q A + YL K+ Sbjct 513 ILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKS 571 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPEC 783 ++H ++ NI L +K+ D G+ G+ E+ I W+APE Sbjct 572 IIHRDLKSNNIFLHE-------DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEV 624 Query 784 LPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP------ 836 + N S D + FG L E+ G+ P + + ++ F + L Sbjct 625 IRMQDKNPYSFQSDVYAFGIVLYELM-TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRS 683 Query 837 SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL----TRLQPHNLADVLTVNPDSPASDPTV 891 +CP+ + L ++CL + +RP F IL + L + + + Sbjct 684 NCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDF 743 Query 892 FHKRYLKKIRDLGEGHFG 909 + G +G Sbjct 744 SLYACASPKTPIQAGGYG 761 >sp|Q5RD00|AAPK2_PONAB 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Pongo abelii OX=9601 GN=PRKAA2 PE=2 SV=1 Length=552 Score = 225 bits (573), Expect = 5e-62, Method: Composition-based stats. Identities = 77/274 (28%), Positives = 106/274 (39%), Gaps = 30/274 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953 + LG G FGKV + + TG VAVK L K+EI L+ Sbjct 15 HYVLGDTLGVGTFGKVKIGEHQ----LTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012 H HIIK + +VMEYV G L DY+ +H + + QQI + Sbjct 71 FRHPHIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE Sbjct 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNIMSDGE---FLRTSCGSPN-YAAPEV 184 Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + D+WS GV LY LL L RG Sbjct 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLF----------------KKIRG 228 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P+ V L+ + + + R T +++ Sbjct 229 GVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDI 262 Score = 179 bits (454), Expect = 2e-46, Method: Composition-based stats. Identities = 58/298 (19%), Positives = 96/298 (32%), Gaps = 39/298 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 Q RV LG GT V G ++ G Sbjct 4 KQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGH----------------------- 40 Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +V +K+L+ D+ + H H+ ++ V + MV EYV G Sbjct 41 -KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGG 99 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L ++ + G V + QQ+ SA+ Y +VH ++ N+LL Sbjct 100 ELFDYICKH-GRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLD-------AHM 151 Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ E + APE + G + +D W G L + Sbjct 152 NAKIADFGLSNIMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSCGVILYALLCG 210 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 P+ + +PE +ATL L +P +R + + I Sbjct 211 TLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWF 268 >sp|Q54TA3|MRKC_DICDI Probable serine/threonine-protein kinase MARK-C OS=Dictyostelium discoideum OX=44689 GN=mrkC PE=3 SV=1 Length=773 Score = 230 bits (587), Expect = 5e-62, Method: Composition-based stats. Identities = 79/299 (26%), Positives = 130/299 (43%), Gaps = 28/299 (9%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 ++ + + H + + LG G FGKV L TN T E VA+K Sbjct 20 NNHHQFNNGGDIIPKKKKNRIMHVGSYEVGKTLGNGTFGKVKLG----TNICTKENVAIK 75 Query 931 ALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK-SLQLVMEYVPLGSLRD 988 +K + + + +EIDI++ L H +I+K + + E+ + L++EYV G L D Sbjct 76 FIKNNKLSGKQKETCFREIDIMKLLDHPNIVKLLDVVDKREEEGTTYLIVEYVSGGELFD 135 Query 989 YL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 Y+ R I + F +Q+ + Y HA +HRDL N+LLD++ +KI DFGL+ Sbjct 136 YIVAREYIKEKEARKFFRQMISAIEYCHANLIVHRDLKPENLLLDSNGDIKISDFGLSNN 195 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPT 1106 + G ++ E + APE LK K+ D+WS GV +Y +L + Sbjct 196 IQPG----KLLESFCGSPLYAAPEILKAEKYLGPPVDIWSLGVIMYAVLCGNLPWE---- 247 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 G +Q +++ + E P E H+++ R T + L Sbjct 248 ------GDSQAEISFNSVHGNYED------PTHLSAEAVHILRRMIVPNPKDRATIQEL 294 Score = 169 bits (429), Expect = 5e-42, Method: Composition-based stats. Identities = 49/314 (16%), Positives = 94/314 (30%), Gaps = 43/314 (14%) Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HH 649 LG GT V G + + V +K + + Sbjct 49 GKTLGNGTFGKVKLG------------------------TNICTKENVAIKFIKNNKLSG 84 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVC---VRGPENIMVTEYVEHGPLDVWLRRERGHV 706 + +M + H ++ + V ++ EYV G L ++ R ++ Sbjct 85 KQKETCFREIDIMKLLDHPNIVKLLDVVDKREEEGTTYLIVEYVSGGELFDYI-VAREYI 143 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 +Q+ SA+ Y +VH ++ N+LL G IK+SD G+ Sbjct 144 KEKEARKFFRQMISAIEYCHANLIVHRDLKPENLLLDSNGD-------IKISDFGLSNNI 196 Query 767 LSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 E + APE L L +D W G + + G P + S +E Sbjct 197 QPGKLLESFCGSPLYAAPEILKAEKY-LGPPVDIWSLGVIMYAVLC-GNLPWEGDSQAEI 254 Query 824 -EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 + + P + + + + P R + + + + + P Sbjct 255 SFNSVHGNYEDPTHLSAEAVHILRRMIVPNPKDRATIQELKNHPWTNIDYQEIPKSHLPP 314 Query 883 DSPASDPTVFHKRY 896 + + Sbjct 315 RDAVHEIKEDIFAH 328 >sp|Q7FAZ2|LERK2_ORYSJ G-type lectin S-receptor-like serine/threonine-protein kinase LECRK2 OS=Oryza sativa subsp. japonica OX=39947 GN=LECRK2 PE=3 SV=1 Length=811 Score = 231 bits (588), Expect = 6e-62, Method: Composition-based stats. Identities = 72/292 (25%), Positives = 118/292 (40%), Gaps = 14/292 (5%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 LG G G V D G +AVK ++ + + + E+ + +H + Sbjct 523 FHEVLGTGASGIVYKGQLQ---DECGTNIAVKKIEK-LQQEAQKEFLVEVQTIGQTFHRN 578 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH-- 1015 +++ G C + EK LV E++ GSL +L S + + A + G+ YLH Sbjct 579 LVRLLGFCNEGTEK--LLVYEFMSNGSLNTFLFNDSHPHWSLRVQVALGVSRGLFYLHEE 636 Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 + IH D+ +N+LLD++ + KI DFGLAK +P + + APE K Sbjct 637 CNKQIIHCDMKPQNILLDDNFVAKISDFGLAKLLPVNQT--QTNTGIRGTRGYVAPEWFK 694 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGE 1132 DV+SFGV L EL+ + + + L A R+ L+ + Sbjct 695 NIGITSKVDVYSFGVILLELVCCRKNVELEVADEEQTILTYWANDCYRCGRIDLLVASDD 754 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 K + C + E S RPT ++ +L + PS + Sbjct 755 EAIFNIKKVERFVAVALWCLQEEPSMRPTMHKVMQMLDGAVQIPTPPDPSSY 806 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 71/406 (17%), Positives = 136/406 (33%), Gaps = 71/406 (17%) Query 486 TVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCF 545 TV + S+ ++D + + G F S L L +L G C Sbjct 430 TVLLKVPRSTNSPSMISSGSSKWKKDKKYWILGSSLFFGS-SVLVNFLLIFVLLFGTYCS 488 Query 546 SLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605 R SN L ++ +++ LG G VY+ Sbjct 489 ITSRKKTQLSQLPSN-----------SGLPSKIFTYRELEKATGGFHEVLGTGASGIVYK 537 Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV 665 G+L+ E + + +K ++ + F + Q Sbjct 538 GQLQDECGTN-----------------------IAVKKIEKLQQEAQKEFLVEVQTIGQT 574 Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL 725 H +L + G C G E ++V E++ +G L+ +L H + ++ VA ++ L YL Sbjct 575 FHRNLVRLLGFCNEGTEKLLVYEFMSNGSLNTFLF-NDSHPHWSLRVQVALGVSRGLFYL 633 Query 726 E---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIP 777 NK ++H ++ +NILL + K+SD G+ + + Sbjct 634 HEECNKQIIHCDMKPQNILLD-------DNFVAKISDFGLAKLLPVNQTQTNTGIRGTRG 686 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP- 836 ++APE +++ +D + FG LLE+ + + E+ + Sbjct 687 YVAPEWFKNIG--ITSKVDVYSFGVILLELVCCRKNVELEVADEEQTILTYWANDCYRCG 744 Query 837 -----------------SCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + + CL EP+ RP+ +++ Sbjct 745 RIDLLVASDDEAIFNIKKVERFVAVALWCLQEEPSMRPTMHKVMQM 790 >sp|O49318|Y2317_ARATH Probable leucine-rich repeat receptor-like protein kinase At2g33170 OS=Arabidopsis thaliana OX=3702 GN=At2g33170 PE=2 SV=1 Length=1124 Score = 234 bits (598), Expect = 6e-62, Method: Composition-based stats. Identities = 78/316 (25%), Positives = 127/316 (40%), Gaps = 24/316 (8%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 +D+ V + + + +G G G V +G+ +AV Sbjct 792 PFFQESDIYFVPKERFTVKDILEATKGFHDSYIVGRGACGTVYKAV-----MPSGKTIAV 846 Query 930 KALKADCGPQHRSG------WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 K L+++ + + ++ EI L + H +I++ C QG S L+ EY+ Sbjct 847 KKLESNREGNNNNSNNTDNSFRAEILTLGKIRHRNIVRLYSFCYHQGSNSNLLLYEYMSR 906 Query 984 GSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLV 1037 GSL + L HS+ A EG+AYLH IHRD+ + N+L+D + Sbjct 907 GSLGELLHGGKSHSMDWPTRFAIALGAAEGLAYLHHDCKPRIIHRDIKSNNILIDENFEA 966 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 +GDFGLAK + + + APE K D++SFGV L ELLT Sbjct 967 HVGDFGLAKVIDMPLS--KSVSAVAGSYGYIAPEYAYTMKVTEKCDIYSFGVVLLELLTG 1024 Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLT-ELLERGERLPRPDKCPCEVY---HLMKNCWE 1153 Q P + +L + + LT E+L+ D + + C + Sbjct 1025 KAPVQ-PLEQGGDLATWTRNHIRDHSLTSEILDPYLTKVEDDVILNHMITVTKIAVLCTK 1083 Query 1154 TEASFRPTFENLIPIL 1169 + S RPT ++ +L Sbjct 1084 SSPSDRPTMREVVLML 1099 Score = 172 bits (435), Expect = 4e-42, Method: Composition-based stats. Identities = 42/247 (17%), Positives = 87/247 (35%), Gaps = 39/247 (16%) Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655 G+G VY+ + + ++ + + E + +F Sbjct 826 GRGACGTVYKAVMPSGKTIAVKKLESNREGNNNNSNN------------------TDNSF 867 Query 656 YETASLMSQVSHTHLAFVHGVCVRGP--ENIMVTEYVEHGPLDVWLRRERGH-VPMAWKM 712 + ++ H ++ ++ C N+++ EY+ G L L + H + + Sbjct 868 RAEILTLGKIRHRNIVRLYSFCYHQGSNSNLLLYEYMSRGSLGELLHGGKSHSMDWPTRF 927 Query 713 VVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----- 764 +A A L+YL + ++H ++ NIL+ + + D G+ Sbjct 928 AIALGAAEGLAYLHHDCKPRIIHRDIKSNNILIDE-------NFEAHVGDFGLAKVIDMP 980 Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + S ++APE ++ D + FG LLE+ G+AP+Q Sbjct 981 LSKSVSAVAGSYGYIAPEYA--YTMKVTEKCDIYSFGVVLLELL-TGKAPVQPLEQGGDL 1037 Query 825 HFYQRQH 831 + R H Sbjct 1038 ATWTRNH 1044 >sp|P28028|BRAF_MOUSE Serine/threonine-protein kinase B-raf OS=Mus musculus OX=10090 GN=Braf PE=1 SV=4 Length=751 Score = 229 bits (585), Expect = 6e-62, Method: Composition-based stats. Identities = 74/291 (25%), Positives = 125/291 (43%), Gaps = 31/291 (11%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEI 948 + + +G G FG V + VAVK L PQ +K E+ Sbjct 435 WEIPDGQITVGQRIGSGSFGTVYKGKWHG-------DVAVKMLNVTAPTPQQLQAFKNEV 487 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQ 1006 +LR H +I+ + G + L +V ++ SL +L + +L+ A+Q Sbjct 488 GVLRKTRHVNILLFMGY---STKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQ 544 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 +GM YLHA+ IHRDL + N+ L D VKIGDFGLA ++ E + Sbjct 545 TAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQF-EQLSGSIL 603 Query 1067 WYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQ--SPPTKFLELIGIAQGQMTV 1121 W APE ++ + + + SDV++FG+ LYEL+T + + + ++G + Sbjct 604 WMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDL 663 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 ++ CP + LM C + + RP F ++ ++ + Sbjct 664 SKVR------------SNCPKAMKRLMAECLKKKRDERPLFPQILASIELL 702 Score = 222 bits (566), Expect = 2e-59, Method: Composition-based stats. Identities = 65/350 (19%), Positives = 123/350 (35%), Gaps = 56/350 (16%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 + +IT +G G+ VY+G+ + V Sbjct 433 DDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD---------------------------V 465 Query 640 VLKVLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +K+L+ + AF ++ + H ++ G + P+ +VT++ E L Sbjct 466 AVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYH 524 Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 L M + +A+Q A + YL K+++H ++ NI L +K+ Sbjct 525 HLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE-------DLTVKI 577 Query 758 SDPGVGL------GALSREERVERIPWLAPECLPGG-ANSLSTAMDKWGFGATLLEICFD 810 D G+ G+ E+ I W+APE + N S D + FG L E+ Sbjct 578 GDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELM-T 636 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP------SCPQ-LATLTSQCLTYEPTQRPSFRTIL 863 G+ P + + ++ F + L +CP+ + L ++CL + +RP F IL Sbjct 637 GQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQIL 696 Query 864 RDL----TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 + L + + + + G +G Sbjct 697 ASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYG 746 >sp|Q9C562|CIPKA_ARATH CBL-interacting serine/threonine-protein kinase 10 OS=Arabidopsis thaliana OX=3702 GN=CIPK10 PE=1 SV=1 Length=479 Score = 223 bits (568), Expect = 6e-62, Method: Composition-based stats. Identities = 53/266 (20%), Positives = 104/266 (39%), Gaps = 26/266 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960 LG+G F KV + T + VA+K + + + K+EI ++R H +++ Sbjct 18 LGQGTFAKVYYG----RSILTNQSVAIKMIDKEKVMKVGLIEQIKREISVMRIARHPNVV 73 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + + + VMEY G L + + + + + Q+ + + H++ Sbjct 74 ELYEVMATKT--RIYFVMEYCKGGELFNKVAKGKLRDDVAWKYFYQLINAVDFCHSREVY 131 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY- 1079 HRD+ N+LLD++ +K+ DFGL+ + + +P + APE + + Sbjct 132 HRDIKPENLLLDDNENLKVSDFGLSALADCKRQDGLLHTTCGTPA-YVAPEVINRKGYDG 190 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS GV L+ LL ++ + + + + P Sbjct 191 TKADIWSCGVVLFVLLAGYLPFHD---------------SNLMEMYRKIGKAD-FKAPSW 234 Query 1140 CPCEVYHLMKNCWETEASFRPTFENL 1165 EV L+ + R T + Sbjct 235 FAPEVRRLLCKMLDPNPETRITIARI 260 Score = 181 bits (459), Expect = 1e-47, Method: Composition-based stats. Identities = 55/311 (18%), Positives = 99/311 (32%), Gaps = 45/311 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 V + LGQGT VY GR + V + Sbjct 5 PSVLTDKYDVGRLLGQGTFAKVYYGRSILTNQS------------------------VAI 40 Query 642 KVLDPSHH---DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 K++D + S+M H ++ ++ V V EY + G L Sbjct 41 KMIDKEKVMKVGLIEQIKREISVMRIARHPNVVELYEVMATKTRIYFVMEYCKGGELFNK 100 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + + + +AWK QL +A+ + ++ + H ++ N+LL + +K+S Sbjct 101 VAKGKLRDDVAWK--YFYQLINAVDFCHSREVYHRDIKPENLLLD-------DNENLKVS 151 Query 759 DPGVGLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 D G+ A + ++APE + T D W G L + G Sbjct 152 DFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRKGYD-GTKADIWSCGVVL-FVLLAGY 209 Query 813 APLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P + E + + P P++ L + L P R + I + Sbjct 210 LPFHDSNLMEMYRKIGKADFKAPSWFAPEVRRLLCKMLDPNPETRITIARIRESSWFRKG 269 Query 872 HNLADVLTVNP 882 ++ Sbjct 270 LHMKQKKMEKR 280 >sp|P54646|AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Homo sapiens OX=9606 GN=PRKAA2 PE=1 SV=2 Length=552 Score = 225 bits (573), Expect = 6e-62, Method: Composition-based stats. Identities = 77/274 (28%), Positives = 106/274 (39%), Gaps = 30/274 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953 + LG G FGKV + + TG VAVK L K+EI L+ Sbjct 15 HYVLGDTLGVGTFGKVKIGEHQ----LTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012 H HIIK + +VMEYV G L DY+ +H + + QQI + Sbjct 71 FRHPHIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE Sbjct 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 184 Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + D+WS GV LY LL L RG Sbjct 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLF----------------KKIRG 228 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P+ V L+ + + + R T +++ Sbjct 229 GVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDI 262 Score = 179 bits (454), Expect = 2e-46, Method: Composition-based stats. Identities = 58/298 (19%), Positives = 96/298 (32%), Gaps = 39/298 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 Q RV LG GT V G ++ G Sbjct 4 KQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGH----------------------- 40 Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +V +K+L+ D+ + H H+ ++ V + MV EYV G Sbjct 41 -KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGG 99 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L ++ + G V + QQ+ SA+ Y +VH ++ N+LL Sbjct 100 ELFDYICKH-GRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLD-------AHM 151 Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ E + APE + G + +D W G L + Sbjct 152 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSCGVILYALLCG 210 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 P+ + +PE +ATL L +P +R + + I Sbjct 211 TLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWF 268 >sp|Q9LMB9|CRK1_ARATH Cysteine-rich receptor-like protein kinase 1 OS=Arabidopsis thaliana OX=3702 GN=CRK1 PE=2 SV=2 Length=615 Score = 226 bits (577), Expect = 6e-62, Method: Composition-based stats. Identities = 64/325 (20%), Positives = 128/325 (39%), Gaps = 18/325 (6%) Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919 ++ ++ + + + + LG+G G V Sbjct 281 TSLGAFISYRRVSRKRKAQVPSCVNFKYEMLEKATESFHDSMKLGQGGAGSVYKGIL--- 337 Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979 G +VAVK L + + E++++ + H+++++ GC + + LV E Sbjct 338 --PDGRIVAVKKL-FFNTREWADQFFNEVNLISGVQHKNLVRLLGCSIEGPKS--LLVYE 392 Query 980 YVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLD 1032 YV SL L H + Q I EG+ YLH IHRD+ N+LLD Sbjct 393 YVHNRSLDQILFMKNTVHILSWKQRFNIIIGISEGLEYLHRGSEVKIIHRDIKTSNILLD 452 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 + KI DFGL +++ G + + + + APE L + + +DV++FGV + Sbjct 453 RNLSPKIADFGLIRSM--GTDKTQTNTGIAGTLGYLAPEYLIKGQLTEKADVYAFGVLII 510 Query 1093 ELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152 E++T ++ ++ L ++ + ++ +V + C Sbjct 511 EIVTGKKNNAFT-QGTSSVLYSVWEHFKANTLDRSIDPRLKGSFVEEEALKVLQIGLLCV 569 Query 1153 ETEASFRPTFENLIPILKTVHEKYQ 1177 ++ RP+ ++ +L+ K++ Sbjct 570 QSSVELRPSMSEIVFMLQNKDSKFE 594 Score = 202 bits (513), Expect = 1e-53, Method: Composition-based stats. Identities = 72/375 (19%), Positives = 128/375 (34%), Gaps = 73/375 (19%) Query 468 DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVR 527 G YL +ST + A+ D +R FP L Sbjct 226 TGCYL-KYSTHKFFD---DAAEHKPDADQRNFIRSSFFPHLSDRDVTRLA---------- 271 Query 528 ELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK 587 AA+ +L + S RR + + P +N + + Sbjct 272 --IAAISLSILTSLGAFISYRRVSRKRKAQV------------PSCVNFKYEMLEK-ATE 316 Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 LGQG +VY+G L V +K L + Sbjct 317 SFHDSMKLGQGGAGSVYKGILPDGRI-------------------------VAVKKLFFN 351 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-- 705 + A F+ +L+S V H +L + G + GP++++V EYV + LD L + Sbjct 352 TREWADQFFNEVNLISGVQHKNLVRLLGCSIEGPKSLLVYEYVHNRSLDQILFMKNTVHI 411 Query 706 VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + + + ++ L YL ++H ++ NILL R + K++D G+ Sbjct 412 LSWKQRFNIIIGISEGLEYLHRGSEVKIIHRDIKTSNILLDR-------NLSPKIADFGL 464 Query 763 GLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + + + + +LAPE L G L+ D + FG ++EI + + Sbjct 465 IRSMGTDKTQTNTGIAGTLGYLAPEYLIKG--QLTEKADVYAFGVLIIEIVTGKKNNAFT 522 Query 818 RSPSEKEHFYQRQHR 832 + S + + Sbjct 523 QGTSSVLYSVWEHFK 537 >sp|Q2RAX3|CIPKX_ORYSJ CBL-interacting protein kinase 33 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK33 PE=2 SV=1 Length=454 Score = 222 bits (565), Expect = 6e-62, Method: Composition-based stats. Identities = 62/270 (23%), Positives = 115/270 (43%), Gaps = 27/270 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959 +GEG F KV + TG+ VA+K L + +H+ K+EI ++ + H ++ Sbjct 18 TIGEGTFAKVKF----ARDTETGDPVAIKILDKEKVLKHKMVEQIKREISTMKLIKHPNV 73 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ + ++ +V+EYV G L D + H + + + QQ+ + Y H++ Sbjct 74 VRIYEVM--GSKTNIYIVLEYVTGGELFDTIVNHGRMREDEARRYFQQLINAVDYCHSRG 131 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N+LLD+ +K+ DFGL+ + + + +P + APE L++ + Sbjct 132 VYHRDLKPENLLLDSYGNLKVSDFGLSALSQQIKDDGLLHTTCGTPN-YVAPEVLEDQGY 190 Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 A +D+WS GV L+ LL + ++ L + + E P Sbjct 191 DGAMADLWSCGVILFVLLAGYLPFED---------------SNLMTLYKKISNAE-FTFP 234 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L+ + R T ++ Sbjct 235 PWTSFPAKRLLTRILDPNPMTRITIPEILE 264 Score = 171 bits (434), Expect = 2e-44, Method: Composition-based stats. Identities = 57/332 (17%), Positives = 103/332 (31%), Gaps = 44/332 (13%) Query 579 LSFHRVDQK--EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 +S +V ++ + +G+GT V RD Sbjct 1 MSTTKVKRRVGKYELGRTIGEGTFAKV------------------------KFARDTETG 36 Query 637 LRVVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 V +K+LD H + S M + H ++ ++ V +V EYV G Sbjct 37 DPVAIKILDKEKVLKHKMVEQIKREISTMKLIKHPNVVRIYEVMGSKTNIYIVLEYVTGG 96 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L + G + QQL +A+ Y ++ + H ++ N+LL G Sbjct 97 ELFDTIVNH-GRMREDEARRYFQQLINAVDYCHSRGVYHRDLKPENLLLDSYG------- 148 Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+SD G+ + + ++APE L D W G L + Sbjct 149 NLKVSDFGLSALSQQIKDDGLLHTTCGTPNYVAPEVLEDQGYD-GAMADLWSCGVILFVL 207 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 S + + + P + L ++ L P R + IL D Sbjct 208 LAGYLPFEDSNLMTLYKKISNAEFTFPPWTSFPAKRLLTRILDPNPMTRITIPEILEDEW 267 Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899 + + + + VF+ Sbjct 268 FKKGYKRPEFDEKYDTTLDDVDAVFNDSEEHH 299 >sp|Q9FGL5|CEPR1_ARATH Receptor protein-tyrosine kinase CEPR1 OS=Arabidopsis thaliana OX=3702 GN=CEPR1 PE=1 SV=1 Length=966 Score = 233 bits (594), Expect = 6e-62, Method: Composition-based stats. Identities = 73/282 (26%), Positives = 116/282 (41%), Gaps = 25/282 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL----KADCGPQHR----SGWKQEIDILRTL 954 +G G G V +GE+VAVK L D + + K E++ L ++ Sbjct 662 VGHGGSGTVYRVELK-----SGEVVAVKKLWSQSNKDSASEDKMHLNKELKTEVETLGSI 716 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMA 1012 H++I+K LV EY+P G+L D L + + A + +G+A Sbjct 717 RHKNIVKLFSYFSSLDCS--LLVYEYMPNGNLWDALHKGFVHLEWRTRHQIAVGVAQGLA 774 Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH + IHRD+ + N+LLD + K+ DFG+AK + + + A Sbjct 775 YLHHDLSPPIIHRDIKSTNILLDVNYQPKVADFGIAKVL-QARGKDSTTTVMAGTYGYLA 833 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR-LTELL 1128 PE K DV+SFGV L EL+T S + ++ ++ L E L Sbjct 834 PEYAYSSKATIKCDVYSFGVVLMELITGKKPVDSCFGENKNIVNWVSTKIDTKEGLIETL 893 Query 1129 ERGERLPRPDKCPC-EVYHLMKNCWETEASFRPTFENLIPIL 1169 ++ RL K + C + RPT ++ +L Sbjct 894 DK--RLSESSKADMINALRVAIRCTSRTPTIRPTMNEVVQLL 933 Score = 192 bits (487), Expect = 1e-48, Method: Composition-based stats. Identities = 70/418 (17%), Positives = 136/418 (33%), Gaps = 83/418 (20%) Query 442 RLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAP-DGMQSL 500 R+ ++ + + P F +L + LI L+ + + Sbjct 523 RIPENLSELL--PTSINFSSNRLSGPIPVSLIR------GGLVESFSDNPNLCIPPTAGS 574 Query 501 RLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSN 560 KFP+ Q+ + S+ + + +L G F LR+ + N Sbjct 575 SDLKFPMCQEPHG------KKKLSSIWAIL--VSVFILVLGVIMFYLRQ------RMSKN 620 Query 561 LIIMRGARA-SPRTLNLSQLSFHRVDQKEITQLSHL------GQGTRTNVYEGRLRVEGS 613 ++ + + SFHR+ + L L G G VY L+ Sbjct 621 RAVIEQDETLASSFFSYDVKSFHRISFDQREILESLVDKNIVGHGGSGTVYRVELKSGE- 679 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVL------DPSHHD---IALAFYETASLMSQ 664 V +K L D + D + + Sbjct 680 ------------------------VVAVKKLWSQSNKDSASEDKMHLNKELKTEVETLGS 715 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 + H ++ + +++V EY+ +G L L + H+ + +A +A L+Y Sbjct 716 IRHKNIVKLFSYFSSLDCSLLVYEYMPNGNLWDALHKGFVHLEWRTRHQIAVGVAQGLAY 775 Query 725 LE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV-----GLGALSREERV-ER 775 L + ++H ++ NILL + K++D G+ G S + Sbjct 776 LHHDLSPPIIHRDIKSTNILLD-------VNYQPKVADFGIAKVLQARGKDSTTTVMAGT 828 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833 +LAPE ++ + D + FG L+E+ G+ P+ S K ++ Sbjct 829 YGYLAPEYA--YSSKATIKCDVYSFGVVLMELI-TGKKPVDSCFGENKNIVNWVSTKI 883 >sp|Q92772|CDKL2_HUMAN Cyclin-dependent kinase-like 2 OS=Homo sapiens OX=9606 GN=CDKL2 PE=1 SV=1 Length=493 Score = 223 bits (568), Expect = 7e-62, Method: Composition-based stats. Identities = 75/283 (27%), Positives = 119/283 (42%), Gaps = 27/283 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG +G V N TG +VA+K L++D + +EI +L+ L HE+++ Sbjct 10 VGEGSYGMVM----KCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 C + +K LV E+V L D L + + + + QI G+ + H+ + I Sbjct 66 LLEVC--KKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNII 123 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFY 1079 HRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L K+ Sbjct 124 HRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVKYG 180 Query 1080 YASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 A DVW+ G + E+ DS + +G + L + G RL Sbjct 181 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL 240 Query 1135 P----------RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P R K V L K C + RP L+ Sbjct 241 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLH 283 Score = 161 bits (408), Expect = 7e-41, Method: Composition-based stats. Identities = 56/320 (18%), Positives = 101/320 (32%), Gaps = 70/320 (22%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-L 644 ++ L +G+G+ V + R + G V +K L Sbjct 1 MEKYENLGLVGEGSYGMVMKCRNKDTGR------------------------IVAIKKFL 36 Query 645 DPSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + + L+ Q+ H +L + VC + +V E+V+H LD L Sbjct 37 ESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDD-LELFP 95 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + Q+ + + + + N++H ++ NIL+++ G+ +KL D G Sbjct 96 NGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFA 148 Query 764 LGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + + V + APE L G A+D W G + E+ Sbjct 149 RTLAAPGEVYTDYVATRWYRAPELLV-GDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSD 207 Query 820 PSEKEHFYQ-------------------RQHRLPEPS------------CPQLATLTSQC 848 + H RLPE + L +C Sbjct 208 IDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKC 267 Query 849 LTYEPTQRPSFRTILRDLTR 868 L +P +RP +L Sbjct 268 LHIDPDKRPFCAELLHHDFF 287 >sp|Q755C4|IPL1_EREGS Spindle assembly checkpoint kinase OS=Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=IPL1 PE=3 SV=1 Length=367 Score = 219 bits (558), Expect = 7e-62, Method: Composition-based stats. Identities = 74/360 (21%), Positives = 139/360 (39%), Gaps = 41/360 (11%) Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 +G P P + +R P + + P +RP+ Sbjct 33 TNGAPPQARVQP-------GKGYRNPGKVLSPI-----RNQEMSPGKRPTLEISELKNVS 80 Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 P S + + LG+G FG+V + +G + A Sbjct 81 PINQAHKTGKARAGGVPLSKLQNLKLADFEIGKVLGKGKFGRVYCV----RHIESGFVCA 136 Query 929 VKALKADCGPQH--RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 +KA++ Q+ +++E++I +L H ++ + G D EK + L+MEY+ G L Sbjct 137 LKAMEKKDIIQYNIEKQFRREVEIQSSLRHPNLTQLYGYFHD--EKRVYLLMEYLVNGEL 194 Query 987 RDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLA 1045 +L R + Q+ + + Y+H ++ +HRD+ N+++ + +K+ DFG + Sbjct 195 YKHLKGRSHFNDVVASYYVYQMADALDYMHERNILHRDIKPENIIIGFNNTIKLTDFGWS 254 Query 1046 KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPP 1105 P+G + R+ V + +PE ++ ++ DVW+ GV YELL + Sbjct 255 VITPKGSK----RKTLCGTVDYLSPELIRSREYNEKVDVWALGVLTYELLVGSPPFEEES 310 Query 1106 TKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + L +L+R L PD E HL+ E + R + + Sbjct 311 KE--------------LTYKRILKRN--LIFPDHVDTEARHLISRLLEYDPGDRIPLKEV 354 Score = 184 bits (468), Expect = 7e-50, Method: Composition-based stats. Identities = 65/348 (19%), Positives = 118/348 (34%), Gaps = 46/348 (13%) Query 534 QGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASP----------RTLNLSQLSFHR 583 G R S R PG+ L I SP R + Sbjct 44 PGKGYRNPGKVLSPIRNQEMSPGKRPTLEISELKNVSPINQAHKTGKARAGGVPLSKLQN 103 Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + + LG+G VY R G + ++ Sbjct 104 LKLADFEIGKVLGKGKFGRVYCVRHIESGFVCALK---------------------AMEK 142 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 D ++I F + S + H +L ++G ++ EY+ +G L L+ R Sbjct 143 KDIIQYNIEKQFRREVEIQSSLRHPNLTQLYGYFHDEKRVYLLMEYLVNGELYKHLKG-R 201 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 H Q+A AL Y+ +N++H ++ NI++ G + IKL+D G Sbjct 202 SHFNDVVASYYVYQMADALDYMHERNILHRDIKPENIII-------GFNNTIKLTDFGWS 254 Query 764 L---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 + R+ + +L+PE + + + +D W G E+ G P + S Sbjct 255 VITPKGSKRKTLCGTVDYLSPELIR--SREYNEKVDVWALGVLTYELLV-GSPPFEEESK 311 Query 821 SEKEHFYQRQHRL-PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 +++ + P+ + L S+ L Y+P R + + + Sbjct 312 ELTYKRILKRNLIFPDHVDTEARHLISRLLEYDPGDRIPLKEVKKHPW 359 >sp|Q9LSV3|WAKLS_ARATH Putative wall-associated receptor kinase-like 16 OS=Arabidopsis thaliana OX=3702 GN=WAKL16 PE=3 SV=1 Length=433 Score = 221 bits (563), Expect = 7e-62, Method: Composition-based stats. Identities = 68/258 (26%), Positives = 109/258 (42%), Gaps = 13/258 (5%) Query 926 MVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 +VA+K + Q + E+ +L + H +++K GCC + E L LV E++ GS Sbjct 132 IVAIKKTRLGDNNQ-VEQFINEVLVLSQINHRNVVKLLGCCLE-TEVPL-LVYEFITGGS 188 Query 986 LRDYLPRH----SIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVK 1038 L D+L S+ L A ++ +AYLH+ IHRD+ N+LLD + K Sbjct 189 LFDHLHGSMFVSSLTWEHRLEIAIEVAGAIAYLHSGASIPIIHRDIKTENILLDENLTAK 248 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 + DFG +K P E G + + PE + SDV+SFGV L EL++ Sbjct 249 VADFGASKLKPMDKEQLTTMVQG--TLGYLDPEYYTTWLLNEKSDVYSFGVVLMELISGQ 306 Query 1099 DSS-QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157 + P L+ RL E+++ + E + C + Sbjct 307 KALCFERPETSKHLVSYFVLATKENRLHEIIDDQVLNEENQREIHEAARVAVECTRLKGE 366 Query 1158 FRPTFENLIPILKTVHEK 1175 RP + L+T+ K Sbjct 367 ERPRMIEVAAELETLRAK 384 Score = 201 bits (510), Expect = 8e-55, Method: Composition-based stats. Identities = 61/362 (17%), Positives = 122/362 (34%), Gaps = 63/362 (17%) Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGS 613 ++I R + A ++ + + LGQG + VY+G L Sbjct 73 KNGGGMLIERLSGAGSSNIDFKIFTEEDMKEATNGYDVSRILGQGGQWTVYKGILPDNSI 132 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 V +K ++ F ++SQ++H ++ + Sbjct 133 -------------------------VAIKKTRLGDNNQVEQFINEVLVLSQINHRNVVKL 167 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK--- 728 G C+ ++V E++ G L L + W ++ +A ++A A++YL + Sbjct 168 LGCCLETEVPLLVYEFITGGSLFDHLHGSMFVSSLTWEHRLEIAIEVAGAIAYLHSGASI 227 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPEC 783 ++H ++ NILL + K++D G +E++ + +L PE Sbjct 228 PIIHRDIKTENILLDE-------NLTAKVADFGASKLKPMDKEQLTTMVQGTLGYLDPEY 280 Query 784 LPGGANSLSTAMDKWGFGATLLEICFDG-----EAPLQSRSPSEKEHFYQRQHRLPEPSC 838 L+ D + FG L+E+ E P S+ +++RL E Sbjct 281 YTTWL--LNEKSDVYSFGVVLMELISGQKALCFERPETSKHLVSYFVLATKENRLHEIID 338 Query 839 PQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 Q+ A + +C + +RP + +L L+ Sbjct 339 DQVLNEENQREIHEAARVAVECTRLKGEERPRMIEVAAELETLRAKTTKHNWLDQYPEEN 398 Query 887 SD 888 Sbjct 399 VH 400 >sp|Q94C95|ATG1A_ARATH Serine/threonine-protein kinase ATG1a OS=Arabidopsis thaliana OX=3702 GN=ATG1A PE=1 SV=1 Length=626 Score = 227 bits (578), Expect = 7e-62, Method: Composition-based stats. Identities = 80/296 (27%), Positives = 123/296 (42%), Gaps = 33/296 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 +G G F V L + +G VAVK + K P+ R +EI IL T+ H +I Sbjct 14 PRIGSGSFAVVWL----AKHRSSGLEVAVKEIDKKLLSPKVRDNLLKEISILSTIDHPNI 69 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018 I++ E + LV+EY G L Y+ RH + A F +Q+ G+ L +H Sbjct 70 IRFYEAIETGD--RIFLVLEYCSGGDLAGYINRHGKVPEAVAKHFMRQLALGLQVLQEKH 127 Query 1019 YIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +IHRDL +N+LL + + +KIGDFG A+++ + E + APE ++ Sbjct 128 FIHRDLKPQNLLLSSKEVTPLLKIGDFGFARSLTPE----SMAETFCGSPLYMAPEIIRN 183 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 K+ +D+WS G L++L+T PP I + + L R Sbjct 184 QKYDAKADLWSAGAILFQLVTGK-----PPFDGNNHIQLFHNIVRDTELK--FPEDTRNE 236 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV----FSVC 1187 C L++ R TF + + Q P V FS C Sbjct 237 IHPDCVDLCRSLLRR----NPIERLTFRE---FFNHMFLREPRQIPDVEHSGFSTC 285 Score = 190 bits (483), Expect = 1e-49, Method: Composition-based stats. Identities = 62/309 (20%), Positives = 107/309 (35%), Gaps = 43/309 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + +G G+ V+ + R G L V +K +D Sbjct 9 DYALGPRIGSGSFAVVWLAKHRSSG------------------------LEVAVKEIDKK 44 Query 648 --HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + + S++S + H ++ + G +V EY G L ++ R G Sbjct 45 LLSPKVRDNLLKEISILSTIDHPNIIRFYEAIETGDRIFLVLEYCSGGDLAGYINRH-GK 103 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 VP A +QLA L L+ K+ +H ++ +N+LL+ + +P +K+ D G Sbjct 104 VPEAVAKHFMRQLALGLQVLQEKHFIHRDLKPQNLLLSS----KEVTPLLKIGDFGFARS 159 Query 766 ALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 E ++APE + D W GA L ++ G+ P + + Sbjct 160 LTPESMAETFCGSPLYMAPEIIRN--QKYDAKADLWSAGAILFQLV-TGKPPFDGNNHIQ 216 Query 823 KEHFYQRQHRLPEPSC------PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 H R L P P L L P +R +FR + +P + D Sbjct 217 LFHNIVRDTELKFPEDTRNEIHPDCVDLCRSLLRRNPIERLTFREFFNHMFLREPRQIPD 276 Query 877 VLTVNPDSP 885 V + Sbjct 277 VEHSGFSTC 285 >sp|Q09137|AAPK2_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Rattus norvegicus OX=10116 GN=Prkaa2 PE=1 SV=1 Length=552 Score = 225 bits (573), Expect = 7e-62, Method: Composition-based stats. Identities = 76/274 (28%), Positives = 106/274 (39%), Gaps = 30/274 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953 + LG G FGKV + + TG VAVK L K+EI L+ Sbjct 15 HYVLGDTLGVGTFGKVKIGEHQ----LTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012 H HIIK + +VMEYV G L DY+ +H + + QQI + Sbjct 71 FRHPHIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVD 128 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE Sbjct 129 YCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 184 Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + D+WS GV LY LL L RG Sbjct 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLF----------------KKIRG 228 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P+ + L+ + + + R T +++ Sbjct 229 GVFYIPEYLNRSIATLLMHMLQVDPLKRATIKDI 262 Score = 179 bits (453), Expect = 3e-46, Method: Composition-based stats. Identities = 58/298 (19%), Positives = 96/298 (32%), Gaps = 39/298 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 Q RV LG GT V G ++ G Sbjct 4 KQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGH----------------------- 40 Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +V +K+L+ D+ + H H+ ++ V + MV EYV G Sbjct 41 -KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGG 99 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L ++ + G V + QQ+ SA+ Y +VH ++ N+LL Sbjct 100 ELFDYICKH-GRVEEVEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLD-------AQM 151 Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ E + APE + G + +D W G L + Sbjct 152 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSCGVILYALLCG 210 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 P+ + +PE +ATL L +P +R + + I Sbjct 211 TLPFDDEHVPTLFKKIRGGVFYIPEYLNRSIATLLMHMLQVDPLKRATIKDIREHEWF 268 >sp|Q9M345|LRK42_ARATH L-type lectin-domain containing receptor kinase IV.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK42 PE=2 SV=1 Length=677 Score = 228 bits (581), Expect = 7e-62, Method: Composition-based stats. Identities = 74/277 (27%), Positives = 116/277 (42%), Gaps = 18/277 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG+V Y T VAVK + D Q + EI + + H +++ Sbjct 353 LGSGGFGRV----YRGILPTTKLEVAVKRVSHD-SKQGMKEFVAEIVSIGRMSHRNLVPL 407 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018 G C +GE L LV +Y+P GSL YL P ++ Q + + G+ YLH + Sbjct 408 LGYCRRRGE--LLLVYDYMPNGSLDKYLYNNPETTLDWKQRSTIIKGVASGLFYLHEEWE 465 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ A NVLLD D ++GDFGLA+ G + + + APE + Sbjct 466 QVVIHRDVKASNVLLDADFNGRLGDFGLARLYDHGSDPQTTH--VVGTLGYLAPEHSRTG 523 Query 1077 KFYYASDVWSFGVTLYELLTHCDS--SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + +DV++FG L E+++ S L+ + E + Sbjct 524 RATTTTDVYAFGAFLLEVVSGRRPIEFHSASDDTFLLVEWVFSLWLRGNIMEAKDPKLGS 583 Query 1135 PRPDKCPCEV-YHLMKNCWETEASFRPTFENLIPILK 1170 D E+ L C ++ RP+ ++ L+ Sbjct 584 SGYDLEEVEMVLKLGLLCSHSDPRARPSMRQVLQYLR 620 Score = 209 bits (531), Expect = 2e-55, Method: Composition-based stats. Identities = 67/310 (22%), Positives = 110/310 (35%), Gaps = 63/310 (20%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 K + LG G VY G L +L V +K + Sbjct 343 ATKGFKEKDLLGSGGFGRVYRGIL------------------------PTTKLEVAVKRV 378 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-R 703 F + ++SH +L + G C R E ++V +Y+ +G LD +L Sbjct 379 SHDSKQGMKEFVAEIVSIGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNNPE 438 Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + + + + +AS L YL + ++H +V N+LL +L D Sbjct 439 TTLDWKQRSTIIKGVASGLFYLHEEWEQVVIHRDVKASNVLLD-------ADFNGRLGDF 491 Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ V + +LAPE G + +T D + FGA LLE+ G P+ Sbjct 492 GLARLYDHGSDPQTTHVVGTLGYLAPEHSRTGRATTTT--DVYAFGAFLLEVVS-GRRPI 548 Query 816 QSRSPSEKEHF-------YQRQHRLPEPSCPQLAT-------------LTSQCLTYEPTQ 855 + S S+ + + E P+L + L C +P Sbjct 549 EFHSASDDTFLLVEWVFSLWLRGNIMEAKDPKLGSSGYDLEEVEMVLKLGLLCSHSDPRA 608 Query 856 RPSFRTILRD 865 RPS R +L+ Sbjct 609 RPSMRQVLQY 618 >sp|Q9S7U9|M2K2_ARATH Mitogen-activated protein kinase kinase 2 OS=Arabidopsis thaliana OX=3702 GN=MKK2 PE=1 SV=2 Length=363 Score = 219 bits (557), Expect = 7e-62, Method: Composition-based stats. Identities = 63/268 (24%), Positives = 116/268 (43%), Gaps = 20/268 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G G V L + TG+ A+K ++ + R QE+ I ++ +++ Sbjct 76 IGKGSSGVVQLVQHK----WTGQFFALKVIQLNIDEAIRKAIAQELKINQSSQCPNLVTS 131 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHA-QHYI 1020 D G ++ L++EY+ GSL D+L +I + L +Q+ +G+ YLH +H I Sbjct 132 YQSFYDNG--AISLILEYMDGGSLADFLKSVKAIPDSYLSAIFRQVLQGLIYLHHDRHII 189 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDL N+L+++ VKI DFG++ + + + +PE + K+ Sbjct 190 HRDLKPSNLLINHRGEVKITDFGVSTVM---TNTAGLANTFVGTYNYMSPERIVGNKYGN 246 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD-K 1139 SD+WS G+ + E T P + +V L E + P Sbjct 247 KSDIWSLGLVVLECATGKFPYAPP--------NQEETWTSVFELMEAIVDQPPPALPSGN 298 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 E+ + C + + + R + + L+ Sbjct 299 FSPELSSFISTCLQKDPNSRSSAKELME 326 Score = 167 bits (424), Expect = 4e-44, Method: Composition-based stats. Identities = 56/317 (18%), Positives = 118/317 (37%), Gaps = 51/317 (16%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 ++ P L+ + + ++ ++ + +G+G+ V Sbjct 48 SQLEPEVLSPIKPADDQLSLSDLDMVKVIGKGSSGVV----------------------Q 85 Query 627 LVPGRDRGQELRVVLKVLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 LV + GQ LKV+ + + I A + + +L + + Sbjct 86 LVQHKWTGQFF--ALKVIQLNIDEAIRKAIAQELKINQSSQCPNLVTSYQSFYDNGAISL 143 Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE-NKNLVHGNVCGRNILLAR 744 + EY++ G L +L+ + +P ++ + +Q+ L YL +++++H ++ N+L+ Sbjct 144 ILEYMDGGSLADFLKSVKA-IPDSYLSAIFRQVLQGLIYLHHDRHIIHRDLKPSNLLINH 202 Query 745 LGLAEGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGF 800 G +K++D GV + V +++PE + G N D W Sbjct 203 RGE-------VKITDFGVSTVMTNTAGLANTFVGTYNYMSPERIVG--NKYGNKSDIWSL 253 Query 801 GATLLEICFDGEAPLQSRSPSE----KEHFYQRQHRLPE------PSCPQLATLTSQCLT 850 G +LE C G+ P + E + P P+L++ S CL Sbjct 254 GLVVLE-CATGKFPYAPPNQEETWTSVFELMEAIVDQPPPALPSGNFSPELSSFISTCLQ 312 Query 851 YEPTQRPSFRTILRDLT 867 +P R S + ++ Sbjct 313 KDPNSRSSAKELMEHPF 329 >sp|Q9SJT0|Y2214_ARATH Probable receptor-like protein kinase At2g21480 OS=Arabidopsis thaliana OX=3702 GN=At2g21480 PE=3 SV=1 Length=871 Score = 231 bits (590), Expect = 7e-62, Method: Composition-based stats. Identities = 73/275 (27%), Positives = 114/275 (41%), Gaps = 17/275 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + D G VA+K Q + + EI +L L H H++ Sbjct 531 IGVGGFGNVYIGTID-----DGTQVAIKRGNP-QSEQGITEFHTEIQMLSKLRHRHLVSL 584 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG---LAQLLLFAQQICEGMAYLHA--- 1016 G C++ E + LV EY+ G RD+L ++ Q L G+ YLH Sbjct 585 IGYCDENAE--MILVYEYMSNGPFRDHLYGKNLSPLTWKQRLEICIGAARGLHYLHTGTA 642 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 Q IHRD+ + N+LLD + K+ DFGL+K V G + V + PE + Sbjct 643 QGIIHRDVKSTNILLDEALVAKVADFGLSKDVAFGQNH--VSTAVKGSFGYLDPEYFRRQ 700 Query 1077 KFYYASDVWSFGVTLYE-LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + SDV+SFGV L E L + P + + L A L ++++ Sbjct 701 QLTDKSDVYSFGVVLLEALCARPAINPQLPREQVNLAEWAMLWKQKGLLEKIIDPHLVGA 760 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + + + C RPT +++ L+ Sbjct 761 VNPESMKKFAEAAEKCLADYGVDRPTMGDVLWNLE 795 Score = 216 bits (551), Expect = 7e-57, Method: Composition-based stats. Identities = 62/309 (20%), Positives = 106/309 (34%), Gaps = 60/309 (19%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 K +G G NVY G + +V +K + Sbjct 522 TKNFDASEIIGVGGFGNVYIGTIDDG-------------------------TQVAIKRGN 556 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-G 704 P F+ ++S++ H HL + G C E I+V EY+ +GP L + Sbjct 557 PQSEQGITEFHTEIQMLSKLRHRHLVSLIGYCDENAEMILVYEYMSNGPFRDHLYGKNLS 616 Query 705 HVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 + ++ + A L YL + ++H +V NILL +A K++D G Sbjct 617 PLTWKQRLEICIGAARGLHYLHTGTAQGIIHRDVKSTNILLDEALVA-------KVADFG 669 Query 762 VGLGALSREERVER-----IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG----- 811 + + V +L PE L+ D + FG LLE Sbjct 670 LSKDVAFGQNHVSTAVKGSFGYLDPEYFR--RQQLTDKSDVYSFGVVLLEALCARPAINP 727 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQL------------ATLTSQCLTYEPTQRPSF 859 + P + + +E ++++ L + P L A +CL RP+ Sbjct 728 QLPREQVNLAEWAMLWKQKGLLEKIIDPHLVGAVNPESMKKFAEAAEKCLADYGVDRPTM 787 Query 860 RTILRDLTR 868 +L +L Sbjct 788 GDVLWNLEY 796 >sp|Q9FP13|SERL2_ORYSJ LRR receptor kinase SERL2 OS=Oryza sativa subsp. japonica OX=39947 GN=SERL2 PE=1 SV=1 Length=640 Score = 227 bits (578), Expect = 7e-62, Method: Composition-based stats. Identities = 71/320 (22%), Positives = 128/320 (40%), Gaps = 15/320 (5%) Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916 R + L + + +V N + LG+G FG V Sbjct 264 WRHRRNRQILFDVDEQQIENVNLGNVKRFSFRELQAATEGFSGKNILGKGGFGNVYRGQL 323 Query 917 DPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQL 976 G +VAVK LK + ++ E++++ H ++++ G C E+ L Sbjct 324 -----PDGTLVAVKRLKDGNAAGGEAQFQTEVEMISLALHRNLLRLYGFCMTATER--LL 376 Query 977 VMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLD 1032 V ++ GS+ L + ++ A G+ YLH Q IHRD+ A NVLLD Sbjct 377 VYPFMSNGSVASRLKAKPALEWGTRRRIAVGAARGLVYLHEQCDPKIIHRDVKAANVLLD 436 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 +GDFGLAK + + V V APE L + +DV+ FG+ L Sbjct 437 EACEAVVGDFGLAKLLDHRESH--VTTAVRGTVGHIAPEYLSTGQSSDRTDVFGFGILLL 494 Query 1093 ELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 EL+T + + + + ++ + + ++ L+++G E+ + Sbjct 495 ELVTGQTALEFGKSSNHKGAMLDWVKKMQSEKKVEVLVDKGLGGGYDRVEVEEMVQVALL 554 Query 1151 CWETEASFRPTFENLIPILK 1170 C + + RP +++ +L+ Sbjct 555 CTQYLPAHRPRMSDVVRMLE 574 Score = 185 bits (470), Expect = 8e-48, Method: Composition-based stats. Identities = 63/320 (20%), Positives = 111/320 (35%), Gaps = 64/320 (20%) Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 N+ + SF + + + + LG+G NVY G+L Sbjct 288 NVKRFSFRELQAATEGFSGKNILGKGGFGNVYRGQLPDG--------------------- 326 Query 633 RGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 V +K L D + F ++S H +L ++G C+ E ++V ++ Sbjct 327 ----TLVAVKRLKDGNAAGGEAQFQTEVEMISLALHRNLLRLYGFCMTATERLLVYPFMS 382 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748 +G + L+ + + + +A A L YL + ++H +V N+LL A Sbjct 383 NGSVASRLKA-KPALEWGTRRRIAVGAARGLVYLHEQCDPKIIHRDVKAANVLLDEACEA 441 Query 749 EGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 + D G+ RE V + +APE L G + S D +GFG Sbjct 442 V-------VGDFGLAKLLDHRESHVTTAVRGTVGHIAPEYLSTGQS--SDRTDVFGFGIL 492 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLP------------------EPSCPQLATLT 845 LLE+ A +S + K ++ ++ + Sbjct 493 LLELVTGQTALEFGKSSNHKGAMLDWVKKMQSEKKVEVLVDKGLGGGYDRVEVEEMVQVA 552 Query 846 SQCLTYEPTQRPSFRTILRD 865 C Y P RP ++R Sbjct 553 LLCTQYLPAHRPRMSDVVRM 572 >sp|O54748|STK3_RAT Serine/threonine-protein kinase 3 OS=Rattus norvegicus OX=10116 GN=Stk3 PE=1 SV=1 Length=491 Score = 223 bits (568), Expect = 7e-62, Method: Composition-based stats. Identities = 63/268 (24%), Positives = 109/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V + + +G++VA+K + + +EI I++ +++K Sbjct 32 KLGEGSYGSV----FKAIHKESGQVVAIKQVPVES---DVQEIIKEISIMQQCDSPYVVK 84 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ + +G+ YLH Sbjct 85 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRK 142 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 143 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 199 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 200 CVADIWSLGITSIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 246 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 + +K C R T L+ Sbjct 247 WSDDFTDFVKKCLVKSPEQRATATQLLQ 274 Score = 198 bits (504), Expect = 2e-53, Method: Composition-based stats. Identities = 56/307 (18%), Positives = 98/307 (32%), Gaps = 44/307 (14%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 + LS+ S + ++ L LG+G+ +V++ + G Sbjct 7 PKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQ--------------- 51 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 V +K + + S+M Q ++ +G + + +V E Sbjct 52 ---------VVAIKQVPVESD--VQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVME 100 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 Y G + +R + + + L YL +H ++ NILL G Sbjct 101 YCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-- 158 Query 749 EGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 KL+D GV R + W+APE + + D W G T Sbjct 159 -----HAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITS 211 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 +E+ +G+ P P R PE +CL P QR + Sbjct 212 IEMA-EGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATAT 270 Query 861 TILRDLT 867 +L+ Sbjct 271 QLLQHPF 277 >sp|Q6CWQ4|IPL1_KLULA Spindle assembly checkpoint kinase OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=IPL1 PE=3 SV=1 Length=361 Score = 219 bits (557), Expect = 7e-62, Method: Composition-based stats. Identities = 68/315 (22%), Positives = 129/315 (41%), Gaps = 29/315 (9%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 + P R L +P+ + + + + LG+G FGKV Sbjct 57 STGPVNNNPRRSLMVKKPNTAHGTRVPILNDHNDKFENMTLQDFEIGKILGKGKFGKVYC 116 Query 914 YCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 + TG + A+KA++ Q+ + +++E++I + H+++ + G D E Sbjct 117 V----KHRETGLICALKAMEKKEIVQYTIQKQFRREVEIQGSFKHKNLTQLYGFFYD--E 170 Query 972 KSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030 K + L+MEYV G L +L + + F Q+ + Y+H+++ +HRD+ N+L Sbjct 171 KRVYLLMEYVYYGELYKFLKNNGPLNETLASYFVYQMANALDYMHSKNILHRDIKPENIL 230 Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 + + +K+ DFG + +G + R+ + + +PE +K ++ DVW+ GV Sbjct 231 IGFNNTIKLTDFGWSVYNEDGQK----RKTLCGTIDYLSPELIKSREYNNKVDVWALGVL 286 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 YELL + + MT R+ L P + L+ Sbjct 287 TYELLVGSPPFEEDTKE-----------MTYRRILRCD-----LKFPLNVSPQARDLIVR 330 Query 1151 CWETEASFRPTFENL 1165 + E S R + Sbjct 331 LLQFEPSKRIPLSEV 345 Score = 186 bits (473), Expect = 1e-50, Method: Composition-based stats. Identities = 60/298 (20%), Positives = 104/298 (35%), Gaps = 36/298 (12%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 LN F + ++ LG+G VY + R G + E Sbjct 85 LNDHNDKFENMTLQDFEIGKILGKGKFGKVYCVKHRETGLICALKAMEKKEIVQYT---- 140 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 I F + H +L ++G ++ EYV +G Sbjct 141 -----------------IQKQFRREVEIQGSFKHKNLTQLYGFFYDEKRVYLLMEYVYYG 183 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L +L+ G + Q+A+AL Y+ +KN++H ++ NIL+ G + Sbjct 184 ELYKFLKNN-GPLNETLASYFVYQMANALDYMHSKNILHRDIKPENILI-------GFNN 235 Query 754 FIKLSDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 IKL+D G + R+ I +L+PE + + + +D W G E+ Sbjct 236 TIKLTDFGWSVYNEDGQKRKTLCGTIDYLSPELIK--SREYNNKVDVWALGVLTYELLV- 292 Query 811 GEAPLQSRSPSEKEHFYQR-QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 G P + + R + P PQ L + L +EP++R + Sbjct 293 GSPPFEEDTKEMTYRRILRCDLKFPLNVSPQARDLIVRLLQFEPSKRIPLSEVKSHAW 350 >sp|A1CPG7|HOG1_ASPCL Mitogen-activated protein kinase hog1 OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=hog1 PE=3 SV=1 Length=365 Score = 219 bits (557), Expect = 7e-62, Method: Composition-based stats. Identities = 67/283 (24%), Positives = 109/283 (39%), Gaps = 29/283 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + TG+ VAVK + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SARDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L + ER P + + L++ + R + Sbjct 252 SLPKRERQPLANKFKNADPDAVDLLERMLVFDPKKRIRATEAL 294 Score = 134 bits (336), Expect = 2e-32, Method: Composition-based stats. Identities = 36/231 (16%), Positives = 74/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + RD+ V +K ++ P ++ Y Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSARDQLTGQPVAVKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSTGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q2V452|CIPK3_ARATH CBL-interacting serine/threonine-protein kinase 3 OS=Arabidopsis thaliana OX=3702 GN=CIPK3 PE=1 SV=2 Length=441 Score = 221 bits (564), Expect = 7e-62, Method: Composition-based stats. Identities = 68/288 (24%), Positives = 120/288 (42%), Gaps = 31/288 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959 +GEG F KV N TGE VA+K L + +H+ ++EI ++ + H ++ Sbjct 19 TIGEGTFAKVKF----ARNSETGEPVALKILDKEKVLKHKMAEQIRREIATMKLIKHPNV 74 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ + + + +++EYV G L D + + + + QQ+ + Y H++ Sbjct 75 VQLYEVMASKTK--IFIILEYVTGGELFDKIVNDGRMKEDEARRYFQQLIHAVDYCHSRG 132 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N+LLD+ +KI DFGL+ + + + +P + APE L + + Sbjct 133 VYHRDLKPENLLLDSYGNLKISDFGLSALSQQVRDDGLLHTSCGTPN-YVAPEVLNDRGY 191 Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 A +D+WS GV LY LL ++ L + + GE P Sbjct 192 DGATADMWSCGVVLYVLLAGYLPFDD---------------SNLMNLYKKISSGE-FNCP 235 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 L+ + R T + + + + Y+ P VF Sbjct 236 PWLSLGAMKLITRILDPNPMTRVTPQEVFED-EWFKKDYK---PPVFE 279 Score = 172 bits (436), Expect = 7e-45, Method: Composition-based stats. Identities = 58/335 (17%), Positives = 101/335 (30%), Gaps = 46/335 (14%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 +N Q RV + E+ +G+GT V R+ Sbjct 1 MNRRQQVKRRVGKYEV--GRTIGEGTFAKV------------------------KFARNS 34 Query 634 GQELRVVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 V LK+LD H +A + M + H ++ ++ V + ++ EYV Sbjct 35 ETGEPVALKILDKEKVLKHKMAEQIRREIATMKLIKHPNVVQLYEVMASKTKIFIILEYV 94 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L + G + QQL A+ Y ++ + H ++ N+LL G Sbjct 95 TGGELFDKI-VNDGRMKEDEARRYFQQLIHAVDYCHSRGVYHRDLKPENLLLDSYG---- 149 Query 751 TSPFIKLSDPGVG------LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 +K+SD G+ ++APE L D W G L Sbjct 150 ---NLKISDFGLSALSQQVRDDGLLHTSCGTPNYVAPEVLNDRGYD-GATADMWSCGVVL 205 Query 805 LEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 + G P + + P L ++ L P R + + + Sbjct 206 Y-VLLAGYLPFDDSNLMNLYKKISSGEFNCPPWLSLGAMKLITRILDPNPMTRVTPQEVF 264 Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898 D + + + + VF Sbjct 265 EDEWFKKDYKPPVFEERDDSNMDDIDAVFKDSEEH 299 >sp|A8XJW8|CST1_CAEBR Serine/threonine-protein kinase cst-1 OS=Caenorhabditis briggsae OX=6238 GN=cst-1 PE=3 SV=2 Length=494 Score = 223 bits (568), Expect = 7e-62, Method: Composition-based stats. Identities = 62/262 (24%), Positives = 113/262 (43%), Gaps = 31/262 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V + + +G ++A+K + D Q +EI I++ ++++K Sbjct 40 KLGEGSYGSV----HKAIHKESGHVLAIKKVPVDTDLQ---EIIKEISIMQQCKSKYVVK 92 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D + R + ++ + +G+ YLH Sbjct 93 YYGSYFKNSD--LWIVMEYCGAGSISDIMRARRKPLSEKEISAVLRDTLKGLQYLHDLKK 150 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ D + K+ DFG+A + + R FW APE ++E + Sbjct 151 IHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIEEIGYD 207 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL--ERGERLPRP 1137 +D+WS G+T E+ + +R ++ + +P Sbjct 208 TKADIWSLGITAIEMAEGRPP---------------YSDIHPMRAIFMIPTKPPPTFKKP 252 Query 1138 DKCPCEVYHLMKNCWETEASFR 1159 ++ E ++ C + R Sbjct 253 EEWSSEFNDFIRCCLIKKPEER 274 Score = 192 bits (489), Expect = 2e-51, Method: Composition-based stats. Identities = 55/302 (18%), Positives = 101/302 (33%), Gaps = 44/302 (15%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L + ++ ++ + LG+G+ +V++ + G Sbjct 20 FKLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHKESGHVL------------------ 61 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +K + P D+ + S+M Q ++ +G + + +V EY G Sbjct 62 ------AIKKV-PVDTDLQ-EIIKEISIMQQCKSKYVVKYYGSYFKNSDLWIVMEYCGAG 113 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 + +R R + V + L YL + +H ++ NILL G+A Sbjct 114 SISDIMRARRKPLSEKEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIA----- 168 Query 754 FIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 KL+D GV R + W+APE + T D W G T +E+ Sbjct 169 --KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIG--YDTKADIWSLGITAIEMA- 223 Query 810 DGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 +G P P + + PE + CL +P +R + + Sbjct 224 EGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRCCLIKKPEERKTALRLCEH 283 Query 866 LT 867 Sbjct 284 TF 285 >sp|A2XQD3|LERK2_ORYSI G-type lectin S-receptor-like serine/threonine-protein kinase LECRK2 OS=Oryza sativa subsp. indica OX=39946 GN=LECRK2 PE=2 SV=1 Length=811 Score = 230 bits (587), Expect = 7e-62, Method: Composition-based stats. Identities = 71/292 (24%), Positives = 118/292 (40%), Gaps = 14/292 (5%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 LG G G V D G +AVK ++ + + + E+ + +H + Sbjct 523 FHEVLGTGASGIVYKGQLQ---DECGTNIAVKKIEK-LQQEAQKEFLVEVQTIGQTFHRN 578 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH-- 1015 +++ G C + EK LV E++ GSL +L + + + A + G+ YLH Sbjct 579 LVRLLGFCNEGTEK--LLVYEFMSNGSLNTFLFNDTHPHWSLRVQVALGVSRGLLYLHEE 636 Query 1016 -AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 + IH D+ +N+LLD++ + KI DFGLAK +P + + APE K Sbjct 637 CNKQIIHCDMKPQNILLDDNFVAKISDFGLAKLLPVNQT--QTNTGIRGTRGYVAPEWFK 694 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGE 1132 DV+SFGV L EL+ + + + L A R+ L+ + Sbjct 695 NIGITSKVDVYSFGVILLELVCCRKNVELEVADEEQTILTYWANDCYRCGRIDLLVAGDD 754 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 K + C + E S RPT ++ +L + PS + Sbjct 755 EAIFNIKKVERFVAVALWCLQEEPSMRPTMHKVMQMLDGAVQIPTPPDPSSY 806 Score = 204 bits (520), Expect = 3e-53, Method: Composition-based stats. Identities = 71/406 (17%), Positives = 136/406 (33%), Gaps = 71/406 (17%) Query 486 TVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCF 545 TV + S+ ++D + + G F S L L +L G C Sbjct 430 TVLLKVPRSTNSPSMISSGSSKWKKDKKYWILGSSLFFGS-SVLVNFLLIFVLLFGTYCS 488 Query 546 SLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605 R SN L ++ +++ LG G VY+ Sbjct 489 ITSRKKTQLSQLPSN-----------SGLPSKIFTYRELEKATGGFHEVLGTGASGIVYK 537 Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV 665 G+L+ E + + +K ++ + F + Q Sbjct 538 GQLQDECGTN-----------------------IAVKKIEKLQQEAQKEFLVEVQTIGQT 574 Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL 725 H +L + G C G E ++V E++ +G L+ +L H + ++ VA ++ L YL Sbjct 575 FHRNLVRLLGFCNEGTEKLLVYEFMSNGSLNTFLF-NDTHPHWSLRVQVALGVSRGLLYL 633 Query 726 E---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIP 777 NK ++H ++ +NILL + K+SD G+ + + Sbjct 634 HEECNKQIIHCDMKPQNILLD-------DNFVAKISDFGLAKLLPVNQTQTNTGIRGTRG 686 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP- 836 ++APE +++ +D + FG LLE+ + + E+ + Sbjct 687 YVAPEWFKNIG--ITSKVDVYSFGVILLELVCCRKNVELEVADEEQTILTYWANDCYRCG 744 Query 837 -----------------SCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + + CL EP+ RP+ +++ Sbjct 745 RIDLLVAGDDEAIFNIKKVERFVAVALWCLQEEPSMRPTMHKVMQM 790 >sp|Q9LFS4|NIK1_ARATH Protein NSP-INTERACTING KINASE 1 OS=Arabidopsis thaliana OX=3702 GN=NIK1 PE=1 SV=1 Length=638 Score = 227 bits (578), Expect = 7e-62, Method: Composition-based stats. Identities = 72/296 (24%), Positives = 125/296 (42%), Gaps = 20/296 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G +G V G +VAVK LK ++ E++++ H ++++ Sbjct 318 LGKGGYGNVYKGIL-----GDSTVVAVKRLKDGGALGGEIQFQTEVEMISLAVHRNLLRL 372 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ---H 1018 G C Q EK LV Y+ GS+ + + + + A G+ YLH Q Sbjct 373 YGFCITQTEK--LLVYPYMSNGSVASRMKAKPVLDWSIRKRIAIGAARGLVYLHEQCDPK 430 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ A N+LLD+ +GDFGLAK + + V V APE L + Sbjct 431 IIHRDVKAANILLDDYCEAVVGDFGLAKLLDHQDSH--VTTAVRGTVGHIAPEYLSTGQS 488 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGE--RL 1134 +DV+ FG+ L EL+T + + + ++ + +L L+++ + Sbjct 489 SEKTDVFGFGILLLELVTGQRAFEFGKAANQKGVMLDWVKKIHQEKKLELLVDKELLKKK 548 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK--TVHEKYQ-GQAPSVFSVC 1187 + E+ + C + RP ++ +L+ + EK++ Q S C Sbjct 549 SYDEIELDEMVRVALLCTQYLPGHRPKMSEVVRMLEGDGLAEKWEASQRSDSVSKC 604 Score = 191 bits (486), Expect = 7e-50, Method: Composition-based stats. Identities = 61/322 (19%), Positives = 112/322 (35%), Gaps = 66/322 (20%) Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 NL + F + + + LG+G NVY+G L Sbjct 296 NLRRFGFRELQIATNNFSSKNLLGKGGYGNVYKGIL------------------------ 331 Query 633 RGQELRVVLKVLDPSHH-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 G V +K L + F ++S H +L ++G C+ E ++V Y+ Sbjct 332 -GDSTVVAVKRLKDGGALGGEIQFQTEVEMISLAVHRNLLRLYGFCITQTEKLLVYPYMS 390 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748 +G + ++ + + + + +A A L YL + ++H +V NILL A Sbjct 391 NGSVASRMKA-KPVLDWSIRKRIAIGAARGLVYLHEQCDPKIIHRDVKAANILLDDYCEA 449 Query 749 EGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 + D G+ ++ V + +APE L G + S D +GFG Sbjct 450 V-------VGDFGLAKLLDHQDSHVTTAVRGTVGHIAPEYLSTGQS--SEKTDVFGFGIL 500 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE--------------------PSCPQLAT 843 LLE+ A ++ ++K ++ + ++ Sbjct 501 LLELVTGQRAFEFGKAANQKGVMLDWVKKIHQEKKLELLVDKELLKKKSYDEIELDEMVR 560 Query 844 LTSQCLTYEPTQRPSFRTILRD 865 + C Y P RP ++R Sbjct 561 VALLCTQYLPGHRPKMSEVVRM 582 >sp|Q9LX29|ACR4L_ARATH Serine/threonine-protein kinase-like protein ACR4 OS=Arabidopsis thaliana OX=3702 GN=ACR4 PE=1 SV=1 Length=895 Score = 232 bits (591), Expect = 8e-62, Method: Composition-based stats. Identities = 72/346 (21%), Positives = 138/346 (40%), Gaps = 20/346 (6%) Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906 +C + T+ +D +++P + K+ +G+G Sbjct 463 RCSEND-TRSSKDSAFTKDNGKIRPDLDELQKRRRARVFTYEELEKAADGFKEESIVGKG 521 Query 907 HFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGC 965 F V G VAVK + + ++ + ++ E+D+L L H H++ G Sbjct 522 SFSCVYKGVLR-----DGTTVAVKRAIMSSDKQKNSNEFRTELDLLSRLNHAHLLSLLGY 576 Query 966 CEDQGEKSLQLVMEYVPLGSLRDYLP------RHSIGLAQLLLFAQQICEGMAYLHA--- 1016 CE+ GE+ LV E++ GSL ++L + + + + A Q G+ YLH Sbjct 577 CEECGER--LLVYEFMAHGSLHNHLHGKNKALKEQLDWVKRVTIAVQAARGIEYLHGYAC 634 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ + N+L+D + ++ DFGL+ + + E + + PE + + Sbjct 635 PPVIHRDIKSSNILIDEEHNARVADFGLS-LLGPVDSGSPLAELPAGTLGYLDPEYYRLH 693 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 SDV+SFGV L E+L+ + + ++ A + + LL+ + P Sbjct 694 YLTTKSDVYSFGVLLLEILSGRKAI-DMHYEEGNIVEWAVPLIKAGDINALLDPVLKHPS 752 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182 + + + C RP+ + + L+ + G S Sbjct 753 EIEALKRIVSVACKCVRMRGKDRPSMDKVTTALERALAQLMGNPSS 798 Score = 198 bits (503), Expect = 9e-51, Method: Composition-based stats. Identities = 50/242 (21%), Positives = 91/242 (38%), Gaps = 45/242 (19%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 + S +G+G+ + VY+G LR G + V ++ Sbjct 512 FKEESIVGKGSFSCVYKGVLRD-----------------------GTTVAVKRAIMSSDK 548 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE----RG 704 + F L+S+++H HL + G C E ++V E++ HG L L + + Sbjct 549 QKNSNEFRTELDLLSRLNHAHLLSLLGYCEECGERLLVYEFMAHGSLHNHLHGKNKALKE 608 Query 705 HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 + ++ +A Q A + YL ++H ++ NIL+ +++D G Sbjct 609 QLDWVKRVTIAVQAARGIEYLHGYACPPVIHRDIKSSNILIDEE-------HNARVADFG 661 Query 762 VGLGALSREER------VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 + L + +L PE + L+T D + FG LLEI +A Sbjct 662 LSLLGPVDSGSPLAELPAGTLGYLDPEYYR--LHYLTTKSDVYSFGVLLLEILSGRKAID 719 Query 816 QS 817 Sbjct 720 MH 721 >sp|Q54DF2|MRKA_DICDI Probable serine/threonine-protein kinase MARK-A OS=Dictyostelium discoideum OX=44689 GN=mrkA PE=3 SV=1 Length=1060 Score = 234 bits (596), Expect = 8e-62, Method: Composition-based stats. Identities = 72/269 (27%), Positives = 116/269 (43%), Gaps = 28/269 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQEIDILRTLYHEHII 960 +G G FGKV L + E VA+K + P+ ++E+ I++ L+H +II Sbjct 114 TIGRGQFGKVKLGYHK---KIPNEKVAIKIINKGKLDPETLKMVQREVRIMKLLHHPNII 170 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019 + E ++L L+MEY G + D++ H + +Q F QI + Y H++ Sbjct 171 RLYEVIE--TSRALYLIMEYAGEGEVMDFMIAHGVLTESQARTFFTQIVSAINYCHSKRA 228 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDL N+LLD +R +KI DFGL+ G ++ SP + +PE + ++ Sbjct 229 VHRDLKPENLLLDCNRQIKIIDFGLSNVFTPGS---YLKTFCGSPT-YASPELILRKEYN 284 Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 + DVWS GV L+ L+T G V ++L P Sbjct 285 GPSVDVWSMGVVLFVLVTGYLPFD--------------GDNYVELFQKILAGNY--TIPS 328 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIP 1167 E L+ + R T E +I Sbjct 329 YLTHECKSLISRMLVVDPDKRATMEEIIN 357 Score = 173 bits (438), Expect = 1e-42, Method: Composition-based stats. Identities = 44/282 (16%), Positives = 96/282 (34%), Gaps = 39/282 (14%) Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651 + +G+G V G + + +V +K+++ D Sbjct 112 IKTIGRGQFGKVKLGYHK-----------------------KIPNEKVAIKIINKGKLDP 148 Query 652 A--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 +M + H ++ ++ V ++ EY G + ++ G + + Sbjct 149 ETLKMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAH-GVLTES 207 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGA 766 Q+ SA++Y +K VH ++ N+LL + IK+ D G+ Sbjct 208 QARTFFTQIVSAINYCHSKRAVHRDLKPENLLLD-------CNRQIKIIDFGLSNVFTPG 260 Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EH 825 + + +PE + + ++D W G L + G P + E + Sbjct 261 SYLKTFCGSPTYASPELILRKEYN-GPSVDVWSMGVVL-FVLVTGYLPFDGDNYVELFQK 318 Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + +P + +L S+ L +P +R + I+ Sbjct 319 ILAGNYTIPSYLTHECKSLISRMLVVDPDKRATMEEIINHPW 360 >sp|Q61846|MELK_MOUSE Maternal embryonic leucine zipper kinase OS=Mus musculus OX=10090 GN=Melk PE=1 SV=2 Length=643 Score = 227 bits (578), Expect = 8e-62, Method: Composition-based stats. Identities = 73/283 (26%), Positives = 123/283 (43%), Gaps = 26/283 (9%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 +Y + +G G F KV L C + TGEMVA+K + + K Sbjct 1 MKDYDELLKYYELYETIGTGGFAKVKLAC----HVLTGEMVAIKIMDKNALGSDLPRVKT 56 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQ 1005 EID L++L H+HI + E + + + +V+EY P G L DY+ + + + + + Sbjct 57 EIDALKSLRHQHICQLYHVLETKNK--IFMVLEYCPGGELFDYIISQDRLSEEETRVVFR 114 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 QI +AY+H+Q Y HRDL N+L D + +K+ DFGL +Y+ + + Sbjct 115 QILSAVAYVHSQGYAHRDLKPENLLFDENHKLKLIDFGLCAKPKGNKDYHL--QTCCGSL 172 Query 1066 FWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 + APE ++ + +DVWS G+ LY L+ V+ L Sbjct 173 AYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDD---------------NVMAL 217 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + RG + P L++ + + R + NL+ Sbjct 218 YKKIMRG-KYEVPKWLSPSSILLLQQMLQVDPKKRISMRNLLN 259 Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 51/318 (16%), Positives = 104/318 (33%), Gaps = 41/318 (13%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647 +G G V + G V +K++D + Sbjct 12 ELYETIGTGGFAKVKLACHVLTGEM------------------------VAIKIMDKNAL 47 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 D+ + + H H+ ++ V + MV EY G L ++ + Sbjct 48 GSDLPR-VKTEIDALKSLRHQHICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSE 106 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV----- 762 ++ V +Q+ SA++Y+ ++ H ++ N+L + +KL D G+ Sbjct 107 EETRV-VFRQILSAVAYVHSQGYAHRDLKPENLLFDE-------NHKLKLIDFGLCAKPK 158 Query 763 GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 G + + + APE + G + L + D W G L + + Sbjct 159 GNKDYHLQTCCGSLAYAAPELIQGKSY-LGSEADVWSMGILLYVLMCGFLPFDDDNVMAL 217 Query 823 KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 + + ++ +P+ P L Q L +P +R S R +L +Q ++ Sbjct 218 YKKIMRGKYEVPKWLSPSSILLLQQMLQVDPKKRISMRNLLNHPWVMQDYSCPVEWQSKT 277 Query 883 DSPASDPTVFHKRYLKKI 900 D + + Sbjct 278 PLTHLDEDCVTELSVHHR 295 >sp|Q93VD3|CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 OS=Arabidopsis thaliana OX=3702 GN=CIPK23 PE=1 SV=1 Length=482 Score = 223 bits (567), Expect = 8e-62, Method: Composition-based stats. Identities = 61/270 (23%), Positives = 114/270 (42%), Gaps = 27/270 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959 LGEG F KV N G+ VA+K + + +++ + K+EI ++ + H ++ Sbjct 36 TLGEGTFAKVKF----ARNVENGDNVAIKVIDKEKVLKNKMIAQIKREISTMKLIKHPNV 91 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018 I+ + + + V+E+V G L D + + + + + QQ+ + Y H++ Sbjct 92 IRMFEVMASKTK--IYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRG 149 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N+LLD + +K+ DFGL+ + E + +P + APE + + Sbjct 150 VYHRDLKPENLLLDANGALKVSDFGLSALPQQVREDGLLHTTCGTPN-YVAPEVINNKGY 208 Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 +D+WS GV L+ L+ + + L + + + E P Sbjct 209 DGAKADLWSCGVILFVLMAGYLPFED---------------SNLTSLYKKIFKAE-FTCP 252 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L+K + + R TF +I Sbjct 253 PWFSASAKKLIKRILDPNPATRITFAEVIE 282 Score = 169 bits (428), Expect = 1e-43, Method: Composition-based stats. Identities = 49/290 (17%), Positives = 88/290 (30%), Gaps = 42/290 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + LG+GT V R G V +KV+D Sbjct 30 KYELGRTLGEGTFAKVKFARNVENGDN------------------------VAIKVIDKE 65 Query 648 ---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + + S M + H ++ + V + V E+V G L + G Sbjct 66 KVLKNKMIAQIKREISTMKLIKHPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSN-G 124 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763 + QQL +A+ Y ++ + H ++ N+LL + +K+SD G+ Sbjct 125 RLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLLD-------ANGALKVSDFGLSA 177 Query 764 -----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 ++APE + D W G L + S Sbjct 178 LPQQVREDGLLHTTCGTPNYVAPEVINNKGYD-GAKADLWSCGVILFVLMAGYLPFEDSN 236 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 S + ++ + P L + L P R +F ++ + Sbjct 237 LTSLYKKIFKAEFTCPPWFSASAKKLIKRILDPNPATRITFAEVIENEWF 286 >sp|Q9NB31|CST1_CAEEL Serine/threonine-protein kinase cst-1 OS=Caenorhabditis elegans OX=6239 GN=cst-1 PE=1 SV=1 Length=497 Score = 223 bits (568), Expect = 8e-62, Method: Composition-based stats. Identities = 62/262 (24%), Positives = 114/262 (44%), Gaps = 31/262 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V + + +G ++A+K + D Q +EI I++ ++++K Sbjct 40 KLGEGSYGSV----HKAIHRESGHVLAIKKVPVDTDLQ---EIIKEISIMQQCKSKYVVK 92 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D + R + ++ + +G+ YLH Sbjct 93 YYGSYFKHSD--LWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKK 150 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ D + K+ DFG+A + + R FW APE ++E + Sbjct 151 IHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIEEIGYD 207 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL--ERGERLPRP 1137 +D+WS G+T E+ + +R ++ + +P Sbjct 208 TKADIWSLGITAIEMAEGRPP---------------YSDIHPMRAIFMIPTKPPPTFKKP 252 Query 1138 DKCPCEVYHLMKNCWETEASFR 1159 ++ E +++C + R Sbjct 253 EEWSSEFNDFIRSCLIKKPEER 274 Score = 194 bits (493), Expect = 6e-52, Method: Composition-based stats. Identities = 58/338 (17%), Positives = 109/338 (32%), Gaps = 44/338 (13%) Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615 +++ S L + ++ ++ + LG+G+ +V++ R G Sbjct 2 PPSTDSSRRNSEEGSSDGFKLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHRESGHVL 61 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675 +K + P D+ + S+M Q ++ +G Sbjct 62 ------------------------AIKKV-PVDTDLQ-EIIKEISIMQQCKSKYVVKYYG 95 Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNV 735 + + +V EY G + +R R + V + L YL + +H ++ Sbjct 96 SYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDI 155 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSL 791 NILL G+A KL+D GV R + W+APE + Sbjct 156 KAGNILLNTDGIA-------KLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIG--Y 206 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQ 847 T D W G T +E+ +G P P + + PE + Sbjct 207 DTKADIWSLGITAIEMA-EGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRS 265 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885 CL +P +R + + + + D+ Sbjct 266 CLIKKPEERKTALRLCEHTFIKNAPGCDIMQLMIQDAQ 303 >sp|Q54H05|KINY_DICDI Probable serine/threonine-protein kinase kinY OS=Dictyostelium discoideum OX=44689 GN=kinY PE=2 SV=1 Length=579 Score = 225 bits (574), Expect = 9e-62, Method: Composition-based stats. Identities = 62/289 (21%), Positives = 125/289 (43%), Gaps = 38/289 (13%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959 +G G +G V ++ VA+K ++ + ++ K+E+ +L+ + H +I Sbjct 37 SIGSGAYGIVYRGTLFNSD------VAIKKIQNEKSEKNEFIKYLKREVAVLKNIQHPNI 90 Query 960 IKYKGCCEDQ-----------GEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQ 1006 +++ G + S +V EY+ G+L + + + + + + Sbjct 91 VQFIGVYYEPLASPSLVNRLLNSSSTWIVTEYIGGGNLHERIKDTKKDFPIELRIKLSLD 150 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLV---KIGDFGLAKAVPEGHEYYRVREDGDS 1063 I MAYLH++ I RDL ++N+L+D+ K+ DFG A+ + + + R + Sbjct 151 IALAMAYLHSRDIIFRDLKSKNILIDDSSSPIRGKVCDFGFARILNKKQQGNRHLSICGT 210 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 APE + ++ + D++SFGV L E++ S+ + +G + Sbjct 211 DSI-MAPELILGMEYDESVDIFSFGVVLLEMILRKKVSKV----------LERGPQSAFE 259 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + + R PD P L +C + + RP F ++I +LK + Sbjct 260 IDQ---DSARQLIPDDIPVLYSDLALDCIKYQPEERPNFSHIIHVLKQL 305 Score = 191 bits (486), Expect = 3e-50, Method: Composition-based stats. Identities = 55/311 (18%), Positives = 111/311 (36%), Gaps = 57/311 (18%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 +D K++ +G G VY G L V +K Sbjct 27 IDIKDLKVGESIGSGAYGIVYRGTLFNSD--------------------------VAIKK 60 Query 644 L---DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG-------------PENIMVT 687 + ++ +++ + H ++ GV +VT Sbjct 61 IQNEKSEKNEFIKYLKREVAVLKNIQHPNIVQFIGVYYEPLASPSLVNRLLNSSSTWIVT 120 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 EY+ G L ++ + P+ ++ ++ +A A++YL +++++ ++ +NIL+ Sbjct 121 EYIGGGNLHERIKDTKKDFPIELRIKLSLDIALAMAYLHSRDIIFRDLKSKNILID---- 176 Query 748 AEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 + K+ D G ++ +APE + G ++D + FG Sbjct 177 DSSSPIRGKVCDFGFARILNKKQQGNRHLSICGTDSIMAPELILGM--EYDESVDIFSFG 234 Query 802 ATLLEICFDGEAPLQ-SRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPS 858 LLE+ + R P Q R +P+ + L C+ Y+P +RP+ Sbjct 235 VVLLEMILRKKVSKVLERGPQSAFEIDQDSARQLIPDDIPVLYSDLALDCIKYQPEERPN 294 Query 859 FRTILRDLTRL 869 F I+ L +L Sbjct 295 FSHIIHVLKQL 305 >sp|Q6IP06|STK3_XENLA Serine/threonine-protein kinase 3 OS=Xenopus laevis OX=8355 GN=stk3 PE=2 SV=1 Length=493 Score = 223 bits (567), Expect = 9e-62, Method: Composition-based stats. Identities = 65/268 (24%), Positives = 110/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V + + +G++VA+K + + Q +EI I++ +++K Sbjct 31 KLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQ---EIIKEISIMQQCDSHYVVK 83 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ + +G+ YLH Sbjct 84 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILRSTLKGLEYLHFMRK 141 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 142 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 198 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 199 CVADIWSLGITSIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 245 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 E +K C R T L+ Sbjct 246 WTDEFTDFVKKCLVKNPEQRATATQLLQ 273 Score = 196 bits (497), Expect = 2e-52, Method: Composition-based stats. Identities = 57/312 (18%), Positives = 100/312 (32%), Gaps = 44/312 (14%) Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 M + LS+ S + ++ L LG+G+ +V++ + G Sbjct 1 MEQPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQ---------- 50 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 V +K + + S+M Q ++ +G + + Sbjct 51 --------------VVAIKQVPVESD--LQEIIKEISIMQQCDSHYVVKYYGSYFKNTDL 94 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 +V EY G + +R + + + L YL +H ++ NILL Sbjct 95 WIVMEYCGAGSVSDIIRLRNKTLTEDEIATILRSTLKGLEYLHFMRKIHRDIKAGNILLN 154 Query 744 RLGLAEGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWG 799 G KL+D GV R + W+APE + + D W Sbjct 155 TEG-------HAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWS 205 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQ 855 G T +E+ +G+ P P R PE + +CL P Q Sbjct 206 LGITSIEMA-EGKPPYADIHPMRAIFMIPTNPPPTFRKPELWTDEFTDFVKKCLVKNPEQ 264 Query 856 RPSFRTILRDLT 867 R + +L+ Sbjct 265 RATATQLLQHPF 276 >sp|Q7XR88|STRK1_ORYSJ Salt tolerance receptor-like cytoplasmic kinase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=STRK1 PE=1 SV=2 Length=361 Score = 218 bits (556), Expect = 9e-62, Method: Composition-based stats. Identities = 66/281 (23%), Positives = 110/281 (39%), Gaps = 23/281 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G F V L + G AVK + ++QE+++L +L H HI++ Sbjct 73 IGHGGFSTVYLASLSSSRLG-----AVKV--HCSSERLHRAFRQELEVLLSLRHPHIVRL 125 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------IGLAQLLLFAQQICEGMAYL 1014 G C+++ E LV EY P G L + L + A+ + A Q+ + YL Sbjct 126 LGYCDERDEG--VLVFEYAPNGDLHERLHCSEVAGGVASVLPWARRVAIAFQVAMALEYL 183 Query 1015 HAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKA-VPEGHEYYRVREDGDSPVFWYAP 1070 H IH D+ A NVLLD + K+ DFG A + P Sbjct 184 HESRHPAVIHGDIKASNVLLDANMNAKLCDFGFAHVGFSATVGCRPSARAVMGSPGYVDP 243 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 ++ SDV+SFGV L EL+T ++ L ++ ++ ++++R Sbjct 244 HLIRSGVATKKSDVYSFGVLLLELVTGKEAVCR--DTGRRLTAAVGPMLSEGKVADVVDR 301 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + L C RP+ +++ L+ Sbjct 302 RLGGEHDGAEAAVMAELAMQCIGDSPGLRPSMADVVRALQE 342 Score = 182 bits (461), Expect = 5e-49, Method: Composition-based stats. Identities = 63/301 (21%), Positives = 99/301 (33%), Gaps = 66/301 (22%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 +G G + VY L G +KV S + Sbjct 71 RVIGHGGFSTVYLASLSSSRLG-------------------------AVKV-HCSSERLH 104 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER------GHV 706 AF + ++ + H H+ + G C E ++V EY +G L L + Sbjct 105 RAFRQELEVLLSLRHPHIVRLLGYCDERDEGVLVFEYAPNGDLHERLHCSEVAGGVASVL 164 Query 707 PMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 P A ++ +A Q+A AL YL ++HG++ N+LL + KL D G Sbjct 165 PWARRVAIAFQVAMALEYLHESRHPAVIHGDIKASNVLLD-------ANMNAKLCDFGFA 217 Query 764 LGALSRE--------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 S + ++ P + G + D + FG LLE+ EA Sbjct 218 HVGFSATVGCRPSARAVMGSPGYVDPHLIRSGVA--TKKSDVYSFGVLLLELVTGKEAVC 275 Query 816 Q----------SRSPSEKEHFYQRQHRLPEPSC----PQLATLTSQCLTYEPTQRPSFRT 861 + SE + RL +A L QC+ P RPS Sbjct 276 RDTGRRLTAAVGPMLSEGKVADVVDRRLGGEHDGAEAAVMAELAMQCIGDSPGLRPSMAD 335 Query 862 I 862 + Sbjct 336 V 336 >sp|A2XW02|STRK1_ORYSI Salt tolerance receptor-like cytoplasmic kinase 1 OS=Oryza sativa subsp. indica OX=39946 GN=OsI_16820 PE=2 SV=1 Length=361 Score = 218 bits (556), Expect = 9e-62, Method: Composition-based stats. Identities = 66/281 (23%), Positives = 110/281 (39%), Gaps = 23/281 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G F V L + G AVK + ++QE+++L +L H HI++ Sbjct 73 IGHGGFSTVYLASLSSSRLG-----AVKV--HCSSERLHRAFRQELEVLLSLRHPHIVRL 125 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--------IGLAQLLLFAQQICEGMAYL 1014 G C+++ E LV EY P G L + L + A+ + A Q+ + YL Sbjct 126 LGYCDERDEG--VLVFEYAPNGDLHERLHCSEVAGGVASVLPWARRVAIAFQVAMALEYL 183 Query 1015 HAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKA-VPEGHEYYRVREDGDSPVFWYAP 1070 H IH D+ A NVLLD + K+ DFG A + P Sbjct 184 HESRHPAVIHGDIKASNVLLDANMNAKLCDFGFAHVGFSATVGCRPSARAVMGSPGYVDP 243 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 ++ SDV+SFGV L EL+T ++ L ++ ++ ++++R Sbjct 244 HLIRSGVATKKSDVYSFGVLLLELVTGKEAVCR--DTGRRLTAAVGPMLSEGKVADVVDR 301 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + L C RP+ +++ L+ Sbjct 302 RLGGEHDGAEAAVMAELAMQCIGDSPGLRPSMADVVRALQE 342 Score = 182 bits (461), Expect = 5e-49, Method: Composition-based stats. Identities = 63/301 (21%), Positives = 99/301 (33%), Gaps = 66/301 (22%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 +G G + VY L G +KV S + Sbjct 71 RVIGHGGFSTVYLASLSSSRLG-------------------------AVKV-HCSSERLH 104 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER------GHV 706 AF + ++ + H H+ + G C E ++V EY +G L L + Sbjct 105 RAFRQELEVLLSLRHPHIVRLLGYCDERDEGVLVFEYAPNGDLHERLHCSEVAGGVASVL 164 Query 707 PMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 P A ++ +A Q+A AL YL ++HG++ N+LL + KL D G Sbjct 165 PWARRVAIAFQVAMALEYLHESRHPAVIHGDIKASNVLLD-------ANMNAKLCDFGFA 217 Query 764 LGALSRE--------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 S + ++ P + G + D + FG LLE+ EA Sbjct 218 HVGFSATVGCRPSARAVMGSPGYVDPHLIRSGVA--TKKSDVYSFGVLLLELVTGKEAVC 275 Query 816 Q----------SRSPSEKEHFYQRQHRLPEPSC----PQLATLTSQCLTYEPTQRPSFRT 861 + SE + RL +A L QC+ P RPS Sbjct 276 RDTGRRLTAAVGPMLSEGKVADVVDRRLGGEHDGAEAAVMAELAMQCIGDSPGLRPSMAD 335 Query 862 I 862 + Sbjct 336 V 336 >sp|A9TXT1|CERK1_PHYPA Chitin elicitor receptor kinase 1 OS=Physcomitrium patens OX=3218 GN=CERK1 PE=2 SV=2 Length=640 Score = 227 bits (578), Expect = 9e-62, Method: Composition-based stats. Identities = 66/296 (22%), Positives = 114/296 (39%), Gaps = 43/296 (15%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G F V + +A+K + C + E+ +L ++H ++++ Sbjct 335 KIGQGGFASVYYGVIR------DQKLAIKKMTLQCT----KEFLAELQVLTNVHHTNLVQ 384 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYLH 1015 G C SL LV EY+ G+L +L R + Q + G+ Y+H Sbjct 385 LIGYCTTN---SLFLVYEYIENGTLDHHLRRRKSDDKPPLSWLQRVQICLDSARGLEYIH 441 Query 1016 AQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 YIHRD+ + N+LLD++ K+ DFGLAK EG + PE Sbjct 442 EHTKPTYIHRDIKSANILLDDNFRAKVADFGLAKLAEEG-----TGTGIVGTFGYMPPEY 496 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHC---------DSSQSPPTKFLELIGIAQGQMTVLR 1123 + DV++FGV L+E+++ ++ Q P + E + VL Sbjct 497 ALYGEVSPKLDVYAFGVVLFEIISGRVAISSALPSENDQQSPAQNRESRTLTSFFEPVLN 556 Query 1124 -------LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 L + ++ ++ L + C RPT + L T+ Sbjct 557 DPDGKTLLPKCIDPALNGEYSLDAVWKMAQLARRCTHQSPDMRPTMRFAVVQLMTL 612 Score = 206 bits (523), Expect = 1e-54, Method: Composition-based stats. Identities = 66/344 (19%), Positives = 116/344 (34%), Gaps = 61/344 (18%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + +GQG +VY G +R + ++ +K + Sbjct 326 ATDNFSLAKKIGQGGFASVYYGVIR--------------------------DQKLAIKKM 359 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 F +++ V HT+L + G C +V EY+E+G LD LRR + Sbjct 360 ---TLQCTKEFLAELQVLTNVHHTNLVQLIGYCTTNS-LFLVYEYIENGTLDHHLRRRKS 415 Query 705 --HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKL 757 P++W ++ + A L Y+ +H ++ NILL + K+ Sbjct 416 DDKPPLSWLQRVQICLDSARGLEYIHEHTKPTYIHRDIKSANILLD-------DNFRAKV 468 Query 758 SDPGVGLGALSREER--VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 +D G+ A V ++ PE G +S +D + FG L EI G + Sbjct 469 ADFGLAKLAEEGTGTGIVGTFGYMPPEYALYG--EVSPKLDVYAFGVVLFEIIS-GRVAI 525 Query 816 QSRSPSEKEHFYQRQHR---------LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 S PSE + Q+R P + P TL +C+ ++ Sbjct 526 SSALPSENDQQSPAQNRESRTLTSFFEPVLNDPDGKTLLPKCIDP---ALNGEYSLDAVW 582 Query 867 TRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910 Q + + V ++ G+F + Sbjct 583 KMAQLARRCTHQSPDMRPTMRFAVVQLMTLASVTQEWDVGYFSR 626 >sp|P34908|BRAF_COTJA Serine/threonine-protein kinase B-raf OS=Coturnix japonica OX=93934 GN=BRAF PE=2 SV=1 Length=807 Score = 230 bits (586), Expect = 9e-62, Method: Composition-based stats. Identities = 76/306 (25%), Positives = 130/306 (42%), Gaps = 31/306 (10%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 + + +SD + + +G G FG V + VAVK L Sbjct 475 RNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-------DVAVKMLNV 527 Query 935 DC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-- 991 PQ +K E+ +LR H +I+ + G + L +V ++ SL +L Sbjct 528 TAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY---STKPQLAIVTQWCEGSSLYHHLHII 584 Query 992 RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 + +L+ A+Q +GM YLHA+ IHRDL + N+ L D VKIGDFGLA Sbjct 585 ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRW 644 Query 1052 HEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQ--SPPT 1106 ++ E + W APE ++ + + + SDV++FG+ LYEL+T + Sbjct 645 SGSHQF-EQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRD 703 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + + ++G + ++ CP + LM C + + RP F ++ Sbjct 704 QIIFMVGRGYLSPDLSKVR------------SNCPKAMKRLMAECLKKKRDERPLFPQIL 751 Query 1167 PILKTV 1172 ++ + Sbjct 752 ASIELL 757 Score = 225 bits (574), Expect = 4e-60, Method: Composition-based stats. Identities = 71/379 (19%), Positives = 131/379 (35%), Gaps = 57/379 (15%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSF-HRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 P P R +TL S + +IT +G G+ VY+G+ + Sbjct 460 PGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGD 519 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSHTH 669 V +K+L+ + AF ++ + H + Sbjct 520 ---------------------------VAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVN 552 Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729 + G + P+ +VT++ E L L M + +A+Q A + YL K+ Sbjct 553 ILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKS 611 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPEC 783 ++H ++ NI L +K+ D G+ G+ E+ I W+APE Sbjct 612 IIHRDLKSNNIFLHE-------DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEV 664 Query 784 LPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP------ 836 + N S D + FG L E+ G+ P + + ++ F + L Sbjct 665 IRMQDKNPYSFQSDVYAFGIVLYELM-TGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRS 723 Query 837 SCPQ-LATLTSQCLTYEPTQRPSFRTILRDL----TRLQPHNLADVLTVNPDSPASDPTV 891 +CP+ + L ++CL + +RP F IL + L + + + Sbjct 724 NCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDF 783 Query 892 FHKRYLKKIRDLGEGHFGK 910 + G +G+ Sbjct 784 SLYACASPKTPIQAGGYGE 802 >sp|O81292|LRK43_ARATH L-type lectin-domain containing receptor kinase IV.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK43 PE=2 SV=1 Length=674 Score = 228 bits (580), Expect = 9e-62, Method: Composition-based stats. Identities = 86/384 (22%), Positives = 146/384 (38%), Gaps = 28/384 (7%) Query 798 WGF---GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPT 854 W F G T + P+ + FY ++R+P L +L + + + Sbjct 261 WSFMVKGKTAPPLTLSKVPKFPRVGPTSLQRFY--KNRMP------LFSLLLIPVLFVVS 312 Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 R I+R + + + + K LG G FG+V Sbjct 313 LIFLVRFIVRRRRKFAEEFEDWETEFGKNRLRFKDLYYATKGFKDKDLLGSGGFGRV--- 369 Query 915 CYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 Y T + +AVK + + Q + EI + + H +++ G C + E L Sbjct 370 -YRGVMPTTKKEIAVKRVSNE-SRQGLKEFVAEIVSIGRMSHRNLVPLLGYCRRRDE--L 425 Query 975 QLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARN 1028 LV +Y+P GSL YL P ++ Q + G+ YLH + IHRD+ A N Sbjct 426 LLVYDYMPNGSLDKYLYDCPEVTLDWKQRFNVIIGVASGLFYLHEEWEQVVIHRDIKASN 485 Query 1029 VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFG 1088 VLLD + ++GDFGLA+ G + R + AP+ ++ + A+DV++FG Sbjct 486 VLLDAEYNGRLGDFGLARLCDHGSDPQTTR--VVGTWGYLAPDHVRTGRATTATDVFAFG 543 Query 1089 VTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 V L E+ + L+ G + + + + V Sbjct 544 VLLLEVACGRRPIEIEIESDESVLLVDSVFGFWIEGNILDATDPNLGSVYDQREVETVLK 603 Query 1147 LMKNCWETEASFRPTFENLIPILK 1170 L C ++ RPT ++ L+ Sbjct 604 LGLLCSHSDPQVRPTMRQVLQYLR 627 Score = 199 bits (505), Expect = 4e-52, Method: Composition-based stats. Identities = 59/304 (19%), Positives = 102/304 (34%), Gaps = 52/304 (17%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 K LG G VY G + + + +K + Sbjct 351 ATKGFKDKDLLGSGGFGRVYRGVM------------------------PTTKKEIAVKRV 386 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ER 703 F + ++SH +L + G C R E ++V +Y+ +G LD +L Sbjct 387 SNESRQGLKEFVAEIVSIGRMSHRNLVPLLGYCRRRDELLLVYDYMPNGSLDKYLYDCPE 446 Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLA-RLGLAEGTSPFIKLSD 759 + + V +AS L YL + ++H ++ N+LL G +L D Sbjct 447 VTLDWKQRFNVIIGVASGLFYLHEEWEQVVIHRDIKASNVLLDAEYNGRLGDFGLARLCD 506 Query 760 PGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 G V +LAP+ + G +TA D + FG LLE+ Sbjct 507 HG---SDPQTTRVVGTWGYLAPDHVRTGRA--TTATDVFAFGVLLLEVACGRRPIEIEIE 561 Query 820 PSEKEHF------YQRQHRLPEPSCPQLATLTSQ------------CLTYEPTQRPSFRT 861 E + + + + + P L ++ Q C +P RP+ R Sbjct 562 SDESVLLVDSVFGFWIEGNILDATDPNLGSVYDQREVETVLKLGLLCSHSDPQVRPTMRQ 621 Query 862 ILRD 865 +L+ Sbjct 622 VLQY 625 >sp|Q5ZJK4|STK4_CHICK Serine/threonine-protein kinase 4 OS=Gallus gallus OX=9031 GN=STK4 PE=2 SV=1 Length=486 Score = 222 bits (566), Expect = 1e-61, Method: Composition-based stats. Identities = 66/268 (25%), Positives = 108/268 (40%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V + + TG++VA+K + + Q +EI I++ H++K Sbjct 34 KLGEGSYGSV----FKAIHKETGQVVAIKQVPVESDLQ---EIIKEISIMQQCDSPHVVK 86 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ Q +G+ YLH Sbjct 87 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLTEEEIATIVQSTLKGLEYLHFMRK 144 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW AP ++E + Sbjct 145 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPGVIQEIGYN 201 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 202 CVADIWSLGITAIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 248 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 +K C R T L+ Sbjct 249 WSDAFTDFVKQCLVKSPEQRATAIQLLQ 276 Score = 194 bits (494), Expect = 4e-52, Method: Composition-based stats. Identities = 57/300 (19%), Positives = 95/300 (32%), Gaps = 44/300 (15%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L + S + ++ L LG+G+ +V++ + G Sbjct 16 LDEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKETGQ---------------------- 53 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K + + S+M Q H+ +G + + +V EY G + Sbjct 54 --VVAIKQVPVESD--LQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSV 109 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + Q L YL +H ++ NILL G Sbjct 110 SDIIRLRNKTLTEEEIATIVQSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-------HA 162 Query 756 KLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL+D GV R + W+AP + + D W G T +E+ +G Sbjct 163 KLADFGVAGQLTDTMAKRNTVIGTPFWMAPGVIQEIG--YNCVADIWSLGITAIEMA-EG 219 Query 812 EAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P P R PE QCL P QR + +L+ Sbjct 220 KPPYADIHPMRAIFMIPTNPPPTFRKPELWSDAFTDFVKQCLVKSPEQRATAIQLLQHPF 279 >sp|Q13188|STK3_HUMAN Serine/threonine-protein kinase 3 OS=Homo sapiens OX=9606 GN=STK3 PE=1 SV=2 Length=491 Score = 223 bits (567), Expect = 1e-61, Method: Composition-based stats. Identities = 64/268 (24%), Positives = 110/268 (41%), Gaps = 27/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG +G V + + +G++VA+K + + Q +EI I++ +++K Sbjct 32 KLGEGSYGSV----FKAIHKESGQVVAIKQVPVESDLQ---EIIKEISIMQQCDSPYVVK 84 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Y G + L +VMEY GS+ D L ++ ++ + +G+ YLH Sbjct 85 YYGSYFKNTD--LWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRK 142 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ A N+LL+ + K+ DFG+A + + R FW APE ++E + Sbjct 143 IHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMA---KRNTVIGTPFWMAPEVIQEIGYN 199 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +D+WS G+T E+ + I R +P+ Sbjct 200 CVADIWSLGITSIEMAEGKPPYAD-IHPMRAIFMIPTNPPPTFR------------KPEL 246 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 + +K C R T L+ Sbjct 247 WSDDFTDFVKKCLVKNPEQRATATQLLQ 274 Score = 197 bits (501), Expect = 6e-53, Method: Composition-based stats. Identities = 56/307 (18%), Positives = 98/307 (32%), Gaps = 44/307 (14%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 + LS+ S + ++ L LG+G+ +V++ + G Sbjct 7 PKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQ--------------- 51 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 V +K + + S+M Q ++ +G + + +V E Sbjct 52 ---------VVAIKQVPVESD--LQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVME 100 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 Y G + +R + + + L YL +H ++ NILL G Sbjct 101 YCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEG-- 158 Query 749 EGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 KL+D GV R + W+APE + + D W G T Sbjct 159 -----HAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIG--YNCVADIWSLGITS 211 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 +E+ +G+ P P R PE +CL P QR + Sbjct 212 IEMA-EGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATAT 270 Query 861 TILRDLT 867 +L+ Sbjct 271 QLLQHPF 277 >sp|Q9LPQ3|M2K7_ARATH Mitogen-activated protein kinase kinase 7 OS=Arabidopsis thaliana OX=3702 GN=MKK7 PE=1 SV=1 Length=307 Score = 216 bits (550), Expect = 1e-61, Method: Composition-based stats. Identities = 75/271 (28%), Positives = 120/271 (44%), Gaps = 26/271 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG G G V Y + TGE+ A+K++ D P +E++ILR +++ Sbjct 49 HVLGRGSSGIV----YKVHHKTTGEIYALKSVNGDMSPAFTRQLAREMEILRRTDSPYVV 104 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + +G E + ++MEY+ G+L R ++ QL F++QI +G++YLH+ + Sbjct 105 RCQGIFEKPIVGEVSILMEYMDGGNLESL--RGAVTEKQLAGFSRQILKGLSYLHSLKIV 162 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE----CLKEY 1076 HRD+ N+LL++ VKI DFG++K + +Y + +PE E Sbjct 163 HRDIKPANLLLNSRNEVKIADFGVSKIITRSLDY---CNSYVGTCAYMSPERFDSAAGEN 219 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 YA D+WSFGV + EL + QGQ + PR Sbjct 220 SDVYAGDIWSFGVMILELFVGHFPL------------LPQGQRPDWATLMCVVCFGEPPR 267 Query 1137 -PDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 P+ C E + C E+S R T L+ Sbjct 268 APEGCSDEFRSFVDCCLRKESSERWTASQLL 298 Score = 169 bits (427), Expect = 4e-45, Method: Composition-based stats. Identities = 62/322 (19%), Positives = 110/322 (34%), Gaps = 58/322 (18%) Query 569 ASPRTLNLSQLSF---------HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEG 619 P +++L SF + + ++ +L LG+G+ VY+ + G + Sbjct 16 VPPLSVHLPWFSFASSTAPVINNGISASDVEKLHVLGRGSSGIVYKVHHKTTGEIYALKS 75 Query 620 KMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR 679 D P ++ + ++ G+ + Sbjct 76 VNGDMSPAF-----------------------TRQLAREMEILRRTDSPYVVRCQGIFEK 112 Query 680 G--PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737 E ++ EY++ G L+ RG V ++Q+ LSYL + +VH ++ Sbjct 113 PIVGEVSILMEYMDGGNLESL----RGAVTEKQLAGFSRQILKGLSYLHSLKIVHRDIKP 168 Query 738 RNILLARLGLAEGTSPFIKLSDPGVG----LGALSREERVERIPWLAPECLPG--GANSL 791 N+LL +K++D GV V +++PE G NS Sbjct 169 ANLLLNSRNE-------VKIADFGVSKIITRSLDYCNSYVGTCAYMSPERFDSAAGENSD 221 Query 792 STAMDKWGFGATLLEICFDGEAP--LQSRSPSEKEHFYQ----RQHRLPEPSCPQLATLT 845 A D W FG +LE+ F G P Q + P R PE + + Sbjct 222 VYAGDIWSFGVMILEL-FVGHFPLLPQGQRPDWATLMCVVCFGEPPRAPEGCSDEFRSFV 280 Query 846 SQCLTYEPTQRPSFRTILRDLT 867 CL E ++R + +L Sbjct 281 DCCLRKESSERWTASQLLGHPF 302 >sp|A0A078CGE6|M3KE1_BRANA MAP3K epsilon protein kinase 1 OS=Brassica napus OX=3708 GN=M3KE1 PE=1 SV=1 Length=1299 Score = 234 bits (598), Expect = 1e-61, Method: Composition-based stats. Identities = 74/294 (25%), Positives = 132/294 (45%), Gaps = 28/294 (10%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + S + ++G+G +G+V + + G+ VA+K + + Sbjct 1 MARQMTSSQFHKSKTLDNKYMLGDEIGKGAYGRVYIG----LDLENGDFVAIKQVSLENI 56 Query 938 PQHR-SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996 Q + QEID+L+ L H++I+KY G + + L +++EYV GSL + + + G Sbjct 57 VQEDLNTIMQEIDLLKNLNHKNIVKYLGSL--KTKTHLHIILEYVENGSLANIIKPNKFG 114 Query 997 ---LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + + ++ Q+ EG+ YLH Q IHRD+ N+L + LVK+ DFG+A + E Sbjct 115 PFPESLVTVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGLVKLADFGVATKLNEAD- 173 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 +W APE ++ ASD+WS G T+ ELLT Sbjct 174 --VNTHSVVGTPYWMAPEVIEMSGVCAASDIWSVGCTVIELLTCVPPYYD---------- 221 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 Q + R+ + + P PD ++ ++ C++ ++ RP + L+ Sbjct 222 -LQPMPALFRIVQ----DDSPPIPDSLSPDITDFLRQCFKKDSRQRPDAKTLLS 270 Score = 203 bits (517), Expect = 7e-52, Method: Composition-based stats. Identities = 61/305 (20%), Positives = 107/305 (35%), Gaps = 43/305 (14%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 R + SQ + + +G+G VY G G Sbjct 3 RQMTSSQFHKSKTLDNKYMLGDEIGKGAYGRVYIGLDLENGDF----------------- 45 Query 632 DRGQELRVVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 V +K + + + + L+ ++H ++ G ++ EY Sbjct 46 -------VAIKQVSLENIVQEDLNTIMQEIDLLKNLNHKNIVKYLGSLKTKTHLHIILEY 98 Query 690 VEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 VE+G L ++ + G P + V Q+ L YL + ++H ++ G NIL + GL Sbjct 99 VENGSLANIIKPNKFGPFPESLVTVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGL- 157 Query 749 EGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 +KL+D GV ++ V W+APE + + + A D W G T+ Sbjct 158 ------VKLADFGVATKLNEADVNTHSVVGTPYWMAPEVIEM--SGVCAASDIWSVGCTV 209 Query 805 LEICFDGEAPLQSRSPSEKEH--FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 +E+ P P +P+ P + QC + QRP +T+ Sbjct 210 IELLTC-VPPYYDLQPMPALFRIVQDDSPPIPDSLSPDITDFLRQCFKKDSRQRPDAKTL 268 Query 863 LRDLT 867 L Sbjct 269 LSHPW 273 >sp|A9RVK2|M3K1B_PHYPA Mitogen-activated protein kinase kinase kinase 1b OS=Physcomitrium patens OX=3218 GN=MEKK1b PE=2 SV=2 Length=764 Score = 229 bits (584), Expect = 1e-61, Method: Composition-based stats. Identities = 70/276 (25%), Positives = 119/276 (43%), Gaps = 31/276 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD----CGPQHRSGWKQEIDILR 952 K +G G FG V D G AVK + G + + EI +L Sbjct 431 WFKGDFIGSGTFGSVYEGI-----DNNGMFFAVKEVSLKDQGKVGQEAIKQLEHEIALLS 485 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 + H +I++Y G ++ ++ L + +E V GSL ++ Q+ + +QI G+ Sbjct 486 DIQHPNIVQYLG--TERDDEKLYIFLELVSKGSLASLYKKYYFVYDQVRAYTKQILSGLK 543 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 YLH + IHRD+ N+L+D + +VK+ DFG+AK V + + + W APE Sbjct 544 YLHDRKIIHRDIKCANILVDTNGVVKLADFGMAKQV----DKLGLLKSFMGSAHWMAPEV 599 Query 1073 LK-EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + ++ + +D+WS G T+ E+ T G++ + + G Sbjct 600 VNPKRQYNFLADIWSLGCTVLEMATGDAPF---------------GELECHSVLWKVGNG 644 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 E PD E+ + C E RPT + L+ Sbjct 645 EGPLIPDDLEDEMKDFISKCLEVTVGNRPTCDMLLT 680 Score = 189 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 53/284 (19%), Positives = 101/284 (36%), Gaps = 36/284 (13%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 T + R + +G GT +VYEG +E + + Sbjct 414 STGRSPGVVSKRPPWDTWFKGDFIGSGTFGSVYEGIDNNGMFFAVKEVSL---------K 464 Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 D+G+ + +K L+ +L+S + H ++ G + + E V Sbjct 465 DQGKVGQEAIKQLEH-----------EIALLSDIQHPNIVQYLGTERDDEKLYIFLELVS 513 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G L ++ + +Q+ S L YL ++ ++H ++ NIL+ T Sbjct 514 KGSLASL--YKKYYFVYDQVRAYTKQILSGLKYLHDRKIIHRDIKCANILVD-------T 564 Query 752 SPFIKLSDPGVGLGALS---REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + +KL+D G+ + + W+APE + + D W G T+LE+ Sbjct 565 NGVVKLADFGMAKQVDKLGLLKSFMGSAHWMAPEVV-NPKRQYNFLADIWSLGCTVLEMA 623 Query 809 FDGEAPLQSRSPSEKEHFYQR--QHRLPEPSCPQLATLTSQCLT 850 G+AP +P+ ++ S+CL Sbjct 624 -TGDAPFGELECHSVLWKVGNGEGPLIPDDLEDEMKDFISKCLE 666 >sp|C0LGX1|Y5524_ARATH Probable LRR receptor-like serine/threonine-protein kinase At5g65240 OS=Arabidopsis thaliana OX=3702 GN=At5g65240 PE=2 SV=1 Length=607 Score = 225 bits (574), Expect = 1e-61, Method: Composition-based stats. Identities = 70/279 (25%), Positives = 115/279 (41%), Gaps = 20/279 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FGKV G VAVK L P +++E++++ H ++++ Sbjct 290 LGQGGFGKVYKGLL-----SDGTKVAVKRLTDFERPGGDEAFQREVEMISVAVHRNLLRL 344 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ 1017 G C Q E+ LV ++ S+ L + + A G+ YLH Sbjct 345 IGFCTTQTER--LLVYPFMQNLSVAYCLREIKPGDPVLDWFRRKQIALGAARGLEYLHEH 402 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRD+ A NVLLD D +GDFGLAK V V + APEC+ Sbjct 403 CNPKIIHRDVKAANVLLDEDFEAVVGDFGLAKLV--DVRRTNVTTQVRGTMGHIAPECIS 460 Query 1075 EYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 K +DV+ +G+ L EL+T D S+ + L+ + RL +++++ Sbjct 461 TGKSSEKTDVFGYGIMLLELVTGQRAIDFSRLEEEDDVLLLDHVKKLEREKRLEDIVDKK 520 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + + + C + RP ++ +L+ Sbjct 521 LDEDYIKEEVEMMIQVALLCTQAAPEERPAMSEVVRMLE 559 Score = 191 bits (485), Expect = 6e-50, Method: Composition-based stats. Identities = 68/364 (19%), Positives = 121/364 (33%), Gaps = 67/364 (18%) Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + ++ + E ++ + LGQG VY+G L Sbjct 268 QLRRFAWRELQLATDEFSEKNVLGQGGFGKVYKGLLSDG--------------------- 306 Query 633 RGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +V +K L D AF ++S H +L + G C E ++V +++ Sbjct 307 ----TKVAVKRLTDFERPGGDEAFQREVEMISVAVHRNLLRLIGFCTTQTERLLVYPFMQ 362 Query 692 HGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745 + + LR + G + W + +A A L YL ++H +V N+LL Sbjct 363 NLSVAYCLREIKPGDPVLDWFRRKQIALGAARGLEYLHEHCNPKIIHRDVKAANVLLDED 422 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800 A + D G+ R V + +APEC+ G + S D +G+ Sbjct 423 FEAV-------VGDFGLAKLVDVRRTNVTTQVRGTMGHIAPECISTGKS--SEKTDVFGY 473 Query 801 GATLLEICFDGEAPLQSRSPSEK-------EHFYQRQHRLPEPSC------------PQL 841 G LLE+ A SR E +R+ RL + + Sbjct 474 GIMLLELVTGQRAIDFSRLEEEDDVLLLDHVKKLEREKRLEDIVDKKLDEDYIKEEVEMM 533 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901 + C P +RP+ ++R L + + + +R+ Sbjct 534 IQVALLCTQAAPEERPAMSEVVRMLEGEGLAERWEEWQNLEVTRQEEFQRLQRRFDWGED 593 Query 902 DLGE 905 + Sbjct 594 SINN 597 >sp|Q28948|AAPK2_PIG 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Sus scrofa OX=9823 GN=PRKAA2 PE=2 SV=2 Length=552 Score = 224 bits (571), Expect = 1e-61, Method: Composition-based stats. Identities = 77/274 (28%), Positives = 106/274 (39%), Gaps = 30/274 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953 + LG G FGKV + + TG VAVK L K+EI L+ Sbjct 15 HYVLGDTLGVGTFGKVKIGEHQ----LTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKL 70 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012 H HIIK + +VMEYV G L DY+ +H + + QQI + Sbjct 71 FRHPHIIKLYQVISTPTD--FFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE Sbjct 129 YCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 184 Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + D+WS GV LY LL L RG Sbjct 185 ISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLF----------------KKIRG 228 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P+ V L+ + + + R T +++ Sbjct 229 GVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDI 262 Score = 178 bits (452), Expect = 5e-46, Method: Composition-based stats. Identities = 58/298 (19%), Positives = 96/298 (32%), Gaps = 39/298 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 Q RV LG GT V G ++ G Sbjct 4 KQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGH----------------------- 40 Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +V +K+L+ D+ + H H+ ++ V + MV EYV G Sbjct 41 -KVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGG 99 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L ++ + G V + QQ+ SA+ Y +VH ++ N+LL Sbjct 100 ELFDYICKH-GRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLD-------AQM 151 Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ E + APE + G + +D W G L + Sbjct 152 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSCGVILYALLCG 210 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 P+ + +PE +ATL L +P +R + + I Sbjct 211 TLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWF 268 >sp|Q2QY53|CIPKW_ORYSJ CBL-interacting protein kinase 32 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK32 PE=2 SV=2 Length=438 Score = 221 bits (562), Expect = 1e-61, Method: Composition-based stats. Identities = 68/297 (23%), Positives = 122/297 (41%), Gaps = 35/297 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959 +GEG F KV + TG+ VA+K L + +H+ K+EI ++ + H ++ Sbjct 18 TIGEGTFAKVKF----ARDTETGDPVAIKILDKEKVLKHKMVEQIKREISTMKLIKHPNV 73 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ + + +V+EYV G L D + H + + + QQ+ + Y H++ Sbjct 74 VRIYEVM--GSKTKIYIVLEYVTGGELFDTIVNHGRMREDEARRYFQQLINAVDYCHSRG 131 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N+LLD+ +K+ DFGL+ + + + +P + APE L++ + Sbjct 132 VYHRDLKPENLLLDSYGNLKVSDFGLSALSQQIKDDGLLHTTCGTPN-YVAPEVLEDQGY 190 Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 A +D+WS GV L+ LL + ++ L + + E P Sbjct 191 DGAMADLWSCGVILFVLLAGYLPFED---------------SNLMTLYKKISNAE-FTFP 234 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI--PILKT------VHEKYQGQAPSVFSV 1186 L+ + R T ++ K EKY V++V Sbjct 235 PWTSFPAKRLLTRILDPNPMTRVTIPEILEDEWFKKGYKRPEFDEKYDTTLDDVYAV 291 Score = 171 bits (434), Expect = 9e-45, Method: Composition-based stats. Identities = 57/332 (17%), Positives = 104/332 (31%), Gaps = 44/332 (13%) Query 579 LSFHRVDQK--EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 +S +V ++ + +G+GT V RD Sbjct 1 MSTTKVKRRVGKYELGRTIGEGTFAKV------------------------KFARDTETG 36 Query 637 LRVVLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 V +K+LD H + S M + H ++ ++ V + +V EYV G Sbjct 37 DPVAIKILDKEKVLKHKMVEQIKREISTMKLIKHPNVVRIYEVMGSKTKIYIVLEYVTGG 96 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L + G + QQL +A+ Y ++ + H ++ N+LL G Sbjct 97 ELFDTIVNH-GRMREDEARRYFQQLINAVDYCHSRGVYHRDLKPENLLLDSYG------- 148 Query 754 FIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +K+SD G+ + + ++APE L D W G L + Sbjct 149 NLKVSDFGLSALSQQIKDDGLLHTTCGTPNYVAPEVLEDQGYD-GAMADLWSCGVILFVL 207 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 S + + + P + L ++ L P R + IL D Sbjct 208 LAGYLPFEDSNLMTLYKKISNAEFTFPPWTSFPAKRLLTRILDPNPMTRVTIPEILEDEW 267 Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899 + + + + VF+ Sbjct 268 FKKGYKRPEFDEKYDTTLDDVYAVFNDSEEHH 299 >sp|C0LGD8|Y1755_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g07550 OS=Arabidopsis thaliana OX=3702 GN=At1g07550 PE=1 SV=1 Length=864 Score = 231 bits (588), Expect = 1e-61, Method: Composition-based stats. Identities = 66/305 (22%), Positives = 121/305 (40%), Gaps = 19/305 (6%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 ++ + +K +G+G FG V C E A+K L Q Sbjct 543 FKSENRRFTYSDVNKMTNNFQVVIGKGGFGVVYQGCL------NNEQAAIKVLSH-SSAQ 595 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----I 995 +K E+++L ++HE ++ G C+D + L L+ E + G+L+++L + Sbjct 596 GYKEFKTEVELLLRVHHEKLVSLIGYCDD--DNGLALIYELMGKGNLKEHLSGKPGCSVL 653 Query 996 GLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 L A + G+ YLH +HRD+ + N+LL + KI DFGL+++ G+ Sbjct 654 SWPIRLKIALESAIGIEYLHTGCKPKIVHRDVKSTNILLSEEFEAKIADFGLSRSFLIGN 713 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 E + PE K SDV+SFGV L E+++ D + ++ Sbjct 714 EAQPT--VVAGTFGYLDPEYHKTSLLSMKSDVYSFGVVLLEIISGQDVI-DLSRENCNIV 770 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + + +++ +V L +C + RP ++ +L Sbjct 771 EWTSFILENGDIESIVDPNLHQDYDTSSAWKVVELAMSCVNRTSKERPNMSQVVHVLNEC 830 Query 1173 HEKYQ 1177 E + Sbjct 831 LETCE 835 Score = 196 bits (499), Expect = 2e-50, Method: Composition-based stats. Identities = 63/305 (21%), Positives = 98/305 (32%), Gaps = 60/305 (20%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 +G+G VY+G L E + +KVL S Sbjct 565 VIGKGGFGVVYQGCLNNE--------------------------QAAIKVLSHSSAQGYK 598 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--K 711 F L+ +V H L + G C ++ E + G L L + G ++W + Sbjct 599 EFKTEVELLLRVHHEKLVSLIGYCDDDNGLALIYELMGKGNLKEHLSGKPGCSVLSWPIR 658 Query 712 MVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL- 767 + +A + A + YL +VH +V NILL+ A K++D G+ L Sbjct 659 LKIALESAIGIEYLHTGCKPKIVHRDVKSTNILLSEEFEA-------KIADFGLSRSFLI 711 Query 768 ----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP--- 820 +L PE + LS D + FG LLEI + SR Sbjct 712 GNEAQPTVVAGTFGYLDPEY--HKTSLLSMKSDVYSFGVVLLEIISGQDVIDLSRENCNI 769 Query 821 SEKEHFYQRQHRLPEPSCPQLA------------TLTSQCLTYEPTQRPSFRTILRDLTR 868 E F + P L L C+ +RP+ ++ L Sbjct 770 VEWTSFILENGDIESIVDPNLHQDYDTSSAWKVVELAMSCVNRTSKERPNMSQVVHVLNE 829 Query 869 LQPHN 873 Sbjct 830 CLETC 834 >sp|Q9TTK0|CDKL2_RABIT Cyclin-dependent kinase-like 2 OS=Oryctolagus cuniculus OX=9986 GN=CDKL2 PE=2 SV=1 Length=566 Score = 224 bits (571), Expect = 1e-61, Method: Composition-based stats. Identities = 75/283 (27%), Positives = 120/283 (42%), Gaps = 27/283 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG +G V N +G +VA+K L++D + +EI +L+ L HE+++ Sbjct 10 VGEGSYGMVM----KCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 C + +K LV E+V L D L + + + + QI G+ + H+ + I Sbjct 66 LLEVC--KKKKRWYLVFEFVDHTILDDLELFPNGLDDQVVQKYLFQIINGIGFCHSHNII 123 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFY 1079 HRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L K+ Sbjct 124 HRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVKYG 180 Query 1080 YASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 A DVW+ G + E+L DS + +G + L + G RL Sbjct 181 KAVDVWAIGCLVTEMLMGEPLFPGDSDIDQLYLIMRCLGNLIPRHQELFYKNPVFAGVRL 240 Query 1135 P----------RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P R K V L K C + RP L+ Sbjct 241 PEIKESEPLERRYPKLSEVVIDLAKKCLHVDPDKRPFCAELLH 283 Score = 162 bits (410), Expect = 1e-40, Method: Composition-based stats. Identities = 59/321 (18%), Positives = 106/321 (33%), Gaps = 72/321 (22%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-L 644 ++ L +G+G+ V + R + G V +K L Sbjct 1 MEKYENLGLVGEGSYGMVMKCRNKDSGR------------------------IVAIKKFL 36 Query 645 DPSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + + L+ Q+ H +L + VC + +V E+V+H LD L Sbjct 37 ESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDD-LELFP 95 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + Q+ + + + + N++H ++ NIL+++ G+ +KL D G Sbjct 96 NGLDDQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFA 148 Query 764 LGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + + V + APE L G A+D W G + E+ GE S Sbjct 149 RTLAAPGEVYTDYVATRWYRAPELLV-GDVKYGKAVDVWAIGCLVTEMLM-GEPLFPGDS 206 Query 820 PSEKEHFYQR--------------------QHRLPEPS------------CPQLATLTSQ 847 ++ + R RLPE + L + Sbjct 207 DIDQLYLIMRCLGNLIPRHQELFYKNPVFAGVRLPEIKESEPLERRYPKLSEVVIDLAKK 266 Query 848 CLTYEPTQRPSFRTILRDLTR 868 CL +P +RP +L Sbjct 267 CLHVDPDKRPFCAELLHHDFF 287 >sp|Q05512|MARK2_MOUSE Serine/threonine-protein kinase MARK2 OS=Mus musculus OX=10090 GN=Mark2 PE=1 SV=3 Length=776 Score = 229 bits (584), Expect = 1e-61, Method: Composition-based stats. Identities = 84/326 (26%), Positives = 128/326 (39%), Gaps = 29/326 (9%) Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 S T PT + + +S S H + ++ +G Sbjct 1 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMLRGRNSATSADEQPHIGNYRLLKTIG 60 Query 905 EGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963 +G+F KV L + TG+ VAVK + K +E+ I++ L H +I+K Sbjct 61 KGNFAKVKL----ARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLF 116 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHR 1022 E EK+L LVMEY G + DYL H + + +QI + Y H + +HR Sbjct 117 EVIE--TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHR 174 Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YA 1081 DL A N+LLD D +KI DFG + G++ + + APE + K Sbjct 175 DLKAENLLLDADMNIKIADFGFSNEFTFGNKL----DTFCGSPPYAAPELFQGKKIDGPE 230 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 DVWS GV LY L++ + L E + RG + P Sbjct 231 VDVWSLGVILYTLVSGSLPFD---------------GQNLKELRERVLRG-KYRIPFYMS 274 Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167 + +L+K S R T E ++ Sbjct 275 TDCENLLKKFLILNPSKRGTLEQIMK 300 Score = 191 bits (484), Expect = 7e-49, Method: Composition-based stats. Identities = 61/355 (17%), Positives = 114/355 (32%), Gaps = 49/355 (14%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 +P SN++ R + S + + L +G+G V R + G Sbjct 27 KPSSKSNMLRGRNSATS---------ADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGK 77 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLA 671 V +K++D + + + + +M ++H ++ Sbjct 78 ------------------------EVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIV 113 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 + V +V EY G + +L G + +Q+ SA+ Y K +V Sbjct 114 KLFEVIETEKTLYLVMEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYCHQKFIV 172 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGA 788 H ++ N+LL IK++D G + P+ APE L G Sbjct 173 HRDLKAENLLLD-------ADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPE-LFQGK 224 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQ 847 +D W G L + G P ++ E R +R+P L + Sbjct 225 KIDGPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 283 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902 L P++R + I++D H ++ P + + Sbjct 284 FLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYT 338 >sp|Q1DUU8|HOG1_COCIM Mitogen-activated protein kinase HOG1 OS=Coccidioides immitis (strain RS) OX=246410 GN=HOG1 PE=3 SV=1 Length=364 Score = 218 bits (555), Expect = 1e-61, Method: Composition-based stats. Identities = 70/305 (23%), Positives = 115/305 (38%), Gaps = 31/305 (10%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADC 936 + + T ++ +G G FG V + T + VAVK + K Sbjct 1 MAEFVRAQIFGTTFEITTRYTDLQPVGMGAFGLVC----SARDQLTNQAVAVKKIMKPFS 56 Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996 P +E+ +L+ L HE++I E + V E + L L + Sbjct 57 TPVLAKRTYRELKLLKHLRHENVISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLE 114 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 + F QI G+ Y+H+ +HRDL N+L++ + +KI DFGLA+ Y Sbjct 115 KQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILINENCDLKICDFGLARVQDPQMTGY- 173 Query 1057 VREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLE 1110 S ++ APE + K+ DVWS G E+L+ + + E Sbjct 174 -----VSTRYYRAPEIMLTWQKYDVEVDVWSAGCIFAEMLSGRPLFPGKDHVNQFSIITE 228 Query 1111 LIGIAQGQM-------TVLRLTELLERGERLPRPDKC----PCEVYHLMKNCWETEASFR 1159 L+G + L+ + L + ER P +K P V L++ + R Sbjct 229 LLGSPPDDVIKTICSANTLQFVQSLPKRERQPLSEKFKGAEPLAV-DLLERMLVFDPKKR 287 Query 1160 PTFEN 1164 T Sbjct 288 ITAAE 292 Score = 135 bits (340), Expect = 5e-33, Method: Composition-based stats. Identities = 37/231 (16%), Positives = 73/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E D + M + RD+ V +K ++ P +A Y Sbjct 10 FGTTFE---ITTRYTDLQPVGMGAFGLVCSARDQLTNQAVAVKKIMKPFSTPVLAKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARVQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ G + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDVWSAGCIFAEMLS-GRPLFPGKDHVNQFSI 225 >sp|Q9SFB6|M3KE2_ARATH MAP3K epsilon protein kinase 2 OS=Arabidopsis thaliana OX=3702 GN=MAP3KE2 PE=2 SV=1 Length=1367 Score = 234 bits (597), Expect = 1e-61, Method: Composition-based stats. Identities = 74/294 (25%), Positives = 133/294 (45%), Gaps = 28/294 (10%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-C 936 + S + ++G+G +G+V + + G+ VA+K + + Sbjct 1 MARQMTSSQFHKSKTLDNKYMLGDEIGKGAYGRVYIG----LDLENGDFVAIKQVSLENI 56 Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996 G + + QEID+L+ L H++I+KY G + + L +++EYV GSL + + + G Sbjct 57 GQEDLNTIMQEIDLLKNLNHKNIVKYLGSL--KTKTHLHIILEYVENGSLANIIKPNKFG 114 Query 997 ---LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + + ++ Q+ EG+ YLH Q IHRD+ N+L + LVK+ DFG+A + E Sbjct 115 PFPESLVTVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGLVKLADFGVATKLNEAD- 173 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 +W APE ++ ASD+WS G T+ ELLT Sbjct 174 --FNTHSVVGTPYWMAPEVIELSGVCAASDIWSVGCTIIELLTCVPPYYD---------- 221 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 Q + R+ + + P PD ++ ++ C++ ++ RP + L+ Sbjct 222 -LQPMPALYRIVQ----DDTPPIPDSLSPDITDFLRLCFKKDSRQRPDAKTLLS 270 Score = 201 bits (512), Expect = 3e-51, Method: Composition-based stats. Identities = 61/305 (20%), Positives = 106/305 (35%), Gaps = 43/305 (14%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 R + SQ + + +G+G VY G G Sbjct 3 RQMTSSQFHKSKTLDNKYMLGDEIGKGAYGRVYIGLDLENGDF----------------- 45 Query 632 DRGQELRVVLKV--LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 V +K L+ + + L+ ++H ++ G ++ EY Sbjct 46 -------VAIKQVSLENIGQEDLNTIMQEIDLLKNLNHKNIVKYLGSLKTKTHLHIILEY 98 Query 690 VEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 VE+G L ++ + G P + V Q+ L YL + ++H ++ G NIL + GL Sbjct 99 VENGSLANIIKPNKFGPFPESLVTVYIAQVLEGLVYLHEQGVIHRDIKGANILTTKEGL- 157 Query 749 EGTSPFIKLSDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 +KL+D GV + V W+APE + + + A D W G T+ Sbjct 158 ------VKLADFGVATKLNEADFNTHSVVGTPYWMAPEVIE--LSGVCAASDIWSVGCTI 209 Query 805 LEICFDGEAPLQSRSPSEKEH--FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 +E+ P P + +P+ P + C + QRP +T+ Sbjct 210 IELLTC-VPPYYDLQPMPALYRIVQDDTPPIPDSLSPDITDFLRLCFKKDSRQRPDAKTL 268 Query 863 LRDLT 867 L Sbjct 269 LSHPW 273 >sp|Q552C1|Y9957_DICDI Probable serine/threonine-protein kinase DDB_G0276181 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0276181 PE=3 SV=1 Length=1555 Score = 234 bits (598), Expect = 2e-61, Method: Composition-based stats. Identities = 64/270 (24%), Positives = 111/270 (41%), Gaps = 37/270 (14%) Query 926 MVAVKALK--ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 +VAVK L AD P+ + E+ +L H +++KY G C + +VMEYVP Sbjct 1057 IVAVKKLHPLADPSPEMIQDFYNEVRVLSMFNHPNVVKYVGGCTKIA--NWSIVMEYVPG 1114 Query 984 GSLRDYLPRHSI--GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN-----DRL 1036 G+L D L + +L A I +G+ YLH+ +H D+ + N+L+ + Sbjct 1115 GNLMDVLANPVLVIPYKLVLRMALDIAKGLHYLHSLGILHLDMKSPNLLVSSLSTSAKVN 1174 Query 1037 VKIGDFGLA------------KAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084 +K+ DF + G ++ W APE ++ + DV Sbjct 1175 IKVADFNTCINRSRITAGFFNRHTGSGDNNKVEKDSKKGTTLWMAPEVIRGAMYSEKCDV 1234 Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144 +SF + ++E++T + + + +G R P P C Sbjct 1235 YSFAIIMWEMVTRKLPYSHIAF--------------NCEVEDQVLKGLRPPIPMHCNKNY 1280 Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHE 1174 LM+ CW+ + RP F+ +I + + E Sbjct 1281 TDLMEQCWDDDPENRPYFDTIIHSISKMIE 1310 Score = 216 bits (550), Expect = 1e-55, Method: Composition-based stats. Identities = 61/330 (18%), Positives = 114/330 (35%), Gaps = 50/330 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGD----------------------PEEGKMDD 623 +KE+ LG G ++Y G + + +D Sbjct 983 EKEVVLHERLGTGATGDIYRGLISQDNLNRHISNQDSSGSNSSGSGSGHNWLIARNPSND 1042 Query 624 EDPLVPGRDRGQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680 G ++ V +K L P ++ FY ++S +H ++ G C + Sbjct 1043 IINKDAIIGSGPQIIVAVKKLHPLADPSPEMIQDFYNEVRVLSMFNHPNVVKYVGGCTKI 1102 Query 681 PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNI 740 +V EYV G L L +P + +A +A L YL + ++H ++ N+ Sbjct 1103 ANWSIVMEYVPGGNLMDVLANPVLVIPYKLVLRMALDIAKGLHYLHSLGILHLDMKSPNL 1162 Query 741 LLARLGLAEGTSPFIKLSDPGVGL-------------------GALSREERVERIPWLAP 781 L++ L + + IK++D + + ++ + W+AP Sbjct 1163 LVSSLSTSAKVN--IKVADFNTCINRSRITAGFFNRHTGSGDNNKVEKDSKKGTTLWMAP 1220 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR--LPEPSCP 839 E + G S D + F + E+ E E + R +P Sbjct 1221 EVIRGAM--YSEKCDVYSFAIIMWEMVTRKLPYSHIAFNCEVEDQVLKGLRPPIPMHCNK 1278 Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 L QC +P RP F TI+ ++++ Sbjct 1279 NYTDLMEQCWDDDPENRPYFDTIIHSISKM 1308 >sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens OX=9606 GN=MAP3K2 PE=1 SV=2 Length=619 Score = 226 bits (575), Expect = 2e-61, Method: Composition-based stats. Identities = 76/290 (26%), Positives = 130/290 (45%), Gaps = 24/290 (8%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP--- 938 D + + + LG+G FG+V L + TG +AVK ++ D Sbjct 341 MDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCY----DVDTGRELAVKQVQFDPDSPET 396 Query 939 -QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IG 996 + + + EI +L+ L HE I++Y GC D EK+L + MEY+P GS++D L + + Sbjct 397 SKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALT 456 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 + +QI EG+ YLH+ +HRD+ N+L D+ VK+GDFG +K + Sbjct 457 ENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGT 516 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 + +W +PE + + +D+WS T+ E+LT + PP E + Sbjct 517 GMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLT-----EKPPWAEFEAMA--- 568 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + ++ + P +K + EA RP+ + L+ Sbjct 569 ------AIFKIATQPTNPKLPPHVSDYTRDFLKRIF-VEAKLRPSADELL 611 Score = 167 bits (422), Expect = 8e-42, Method: Composition-based stats. Identities = 60/335 (18%), Positives = 102/335 (30%), Gaps = 49/335 (15%) Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQK---EITQLSHLGQGTRTNVYEGRLRVE 611 P + I RG+ TL + +S + LGQG VY Sbjct 319 PEYDDSRIRRRGSDIDNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVY------- 371 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE---TASLMSQVSHT 668 L D G+EL V DP + + L+ + H Sbjct 372 ---------------LCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHE 416 Query 669 HLAFVHGVCVRGPE--NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726 + +G E + EY+ G + L+ G + +Q+ + YL Sbjct 417 RIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKA-YGALTENVTRKYTRQILEGVHYLH 475 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-------VGLGALSREERVERIPWL 779 + +VH ++ G NIL ++ +KL D G + L + W+ Sbjct 476 SNMIVHRDIKGANIL-------RDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWM 528 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP 839 +PE + G D W T++E+ E P + + F P Sbjct 529 SPEVISG--EGYGRKADIWSVACTVVEMLT--EKPPWAEFEAMAAIFKIATQPTNPKLPP 584 Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 ++ T L + + L + H Sbjct 585 HVSDYTRDFLKRIFVEAKLRPSADELLRHMFVHYH 619 >sp|Q64303|PAK2_RAT Serine/threonine-protein kinase PAK 2 OS=Rattus norvegicus OX=10116 GN=Pak2 PE=1 SV=1 Length=524 Score = 223 bits (568), Expect = 2e-61, Method: Composition-based stats. Identities = 63/275 (23%), Positives = 110/275 (40%), Gaps = 23/275 (8%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 K+ + +G+G G V + T+ G+ VA+K + P+ + EI +++ Sbjct 245 PKKKYTRYEKIGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINEILVMK 299 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 L + +I+ + E L +VMEY+ GSL D + + AQ+ ++ + + Sbjct 300 ELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALE 357 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 +LHA IHRD+ + NVLL + VK+ DFG + R +W APE Sbjct 358 FLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEV 414 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + D+WS G+ E++ PP + T Sbjct 415 VTRKAYGPKVDIWSLGIMAIEMV-----EGEPPYLNENPLRALYLIATNGT--------P 461 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L P+K + C E + R + + L+ Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496 Score = 187 bits (475), Expect = 2e-49, Method: Composition-based stats. Identities = 60/340 (18%), Positives = 115/340 (34%), Gaps = 56/340 (16%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV------------DQKEITQLSHL 595 R P P + + GA++S + ++++ + +K+ T+ + Sbjct 196 RSVIDPIPAPVGDSNVDSGAKSSDKQKKKAKMTDEEIMEKLRTIVSIGDPKKKYTRYEKI 255 Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655 GQG V+ D V +K ++ Sbjct 256 GQGASGTVF------------------------TATDVALGQEVAIKQINLQKQPKKELI 291 Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715 +M ++ + ++ + G E +V EY+ G L + + A V Sbjct 292 INEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVV--TETCMDEAQIAAVC 349 Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREE 771 ++ AL +L ++H ++ N+LL G +KL+D G R Sbjct 350 RECLQALEFLHANQVIHRDIKSDNVLL-------GMEGSVKLTDFGFCAQITPEQSKRST 402 Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 V W+APE + A +D W G +E+ +GE P + +P + Sbjct 403 MVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNG 459 Query 832 RL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 PE P ++CL + +R S + +L+ Sbjct 460 TPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPF 499 >sp|Q29502|PAK2_RABIT Serine/threonine-protein kinase PAK 2 OS=Oryctolagus cuniculus OX=9986 GN=PAK2 PE=1 SV=1 Length=524 Score = 223 bits (568), Expect = 2e-61, Method: Composition-based stats. Identities = 63/275 (23%), Positives = 110/275 (40%), Gaps = 23/275 (8%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 K+ + +G+G G V + T+ G+ VA+K + P+ + EI +++ Sbjct 245 PKKKYTRYEKIGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINEILVMK 299 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 L + +I+ + E L +VMEY+ GSL D + + AQ+ ++ + + Sbjct 300 ELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALE 357 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 +LHA IHRD+ + NVLL + VK+ DFG + R +W APE Sbjct 358 FLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEV 414 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + D+WS G+ E++ PP + T Sbjct 415 VTRKAYGPKVDIWSLGIMAIEMV-----EGEPPYLNENPLRALYLIATNGT--------P 461 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L P+K + C E + R + + L+ Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496 Score = 187 bits (474), Expect = 3e-49, Method: Composition-based stats. Identities = 60/340 (18%), Positives = 115/340 (34%), Gaps = 56/340 (16%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV------------DQKEITQLSHL 595 R P P + + GA++S + ++++ + +K+ T+ + Sbjct 196 RSVIDPIPAPVGDSHVDSGAKSSDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKI 255 Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655 GQG V+ D V +K ++ Sbjct 256 GQGASGTVF------------------------TATDVALGQEVAIKQINLQKQPKKELI 291 Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715 +M ++ + ++ + G E +V EY+ G L + + A V Sbjct 292 INEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVV--TETCMDEAQIAAVC 349 Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREE 771 ++ AL +L ++H ++ N+LL G +KL+D G R Sbjct 350 RECLQALEFLHANQVIHRDIKSDNVLL-------GMEGSVKLTDFGFCAQITPEQSKRST 402 Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 V W+APE + A +D W G +E+ +GE P + +P + Sbjct 403 MVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNG 459 Query 832 RL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 PE P ++CL + +R S + +L+ Sbjct 460 TPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPF 499 >sp|Q8CIN4|PAK2_MOUSE Serine/threonine-protein kinase PAK 2 OS=Mus musculus OX=10090 GN=Pak2 PE=1 SV=1 Length=524 Score = 223 bits (568), Expect = 2e-61, Method: Composition-based stats. Identities = 63/275 (23%), Positives = 110/275 (40%), Gaps = 23/275 (8%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 K+ + +G+G G V + T+ G+ VA+K + P+ + EI +++ Sbjct 245 PKKKYTRYEKIGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINEILVMK 299 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 L + +I+ + E L +VMEY+ GSL D + + AQ+ ++ + + Sbjct 300 ELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALE 357 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 +LHA IHRD+ + NVLL + VK+ DFG + R +W APE Sbjct 358 FLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEV 414 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + D+WS G+ E++ PP + T Sbjct 415 VTRKAYGPKVDIWSLGIMAIEMV-----EGEPPYLNENPLRALYLIATNGT--------P 461 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L P+K + C E + R + + L+ Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496 Score = 187 bits (475), Expect = 2e-49, Method: Composition-based stats. Identities = 60/340 (18%), Positives = 115/340 (34%), Gaps = 56/340 (16%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV------------DQKEITQLSHL 595 R P P + + GA++S + ++++ + +K+ T+ + Sbjct 196 RSVIDPIPAPVGDSNVDSGAKSSDKQKKKAKMTDEEIMEKLRTIVSIGDPKKKYTRYEKI 255 Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655 GQG V+ D V +K ++ Sbjct 256 GQGASGTVF------------------------TATDVALGQEVAIKQINLQKQPKKELI 291 Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715 +M ++ + ++ + G E +V EY+ G L + + A V Sbjct 292 INEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVV--TETCMDEAQIAAVC 349 Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREE 771 ++ AL +L ++H ++ N+LL G +KL+D G R Sbjct 350 RECLQALEFLHANQVIHRDIKSDNVLL-------GMEGSVKLTDFGFCAQITPEQSKRST 402 Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 V W+APE + A +D W G +E+ +GE P + +P + Sbjct 403 MVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNG 459 Query 832 RL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 PE P ++CL + +R S + +L+ Sbjct 460 TPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPF 499 >sp|Q13177|PAK2_HUMAN Serine/threonine-protein kinase PAK 2 OS=Homo sapiens OX=9606 GN=PAK2 PE=1 SV=3 Length=524 Score = 223 bits (568), Expect = 2e-61, Method: Composition-based stats. Identities = 63/275 (23%), Positives = 110/275 (40%), Gaps = 23/275 (8%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 K+ + +G+G G V + T+ G+ VA+K + P+ + EI +++ Sbjct 245 PKKKYTRYEKIGQGASGTV----FTATDVALGQEVAIKQINLQKQPK-KELIINEILVMK 299 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 L + +I+ + E L +VMEY+ GSL D + + AQ+ ++ + + Sbjct 300 ELKNPNIVNFLDSYLVGDE--LFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALE 357 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 +LHA IHRD+ + NVLL + VK+ DFG + R +W APE Sbjct 358 FLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEV 414 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + D+WS G+ E++ PP + T Sbjct 415 VTRKAYGPKVDIWSLGIMAIEMV-----EGEPPYLNENPLRALYLIATNGT--------P 461 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L P+K + C E + R + + L+ Sbjct 462 ELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496 Score = 184 bits (466), Expect = 4e-48, Method: Composition-based stats. Identities = 58/340 (17%), Positives = 113/340 (33%), Gaps = 56/340 (16%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV------------DQKEITQLSHL 595 R P P + + A++ + ++++ + +K+ T+ + Sbjct 196 RSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKI 255 Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655 GQG V+ D V +K ++ Sbjct 256 GQGASGTVF------------------------TATDVALGQEVAIKQINLQKQPKKELI 291 Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715 +M ++ + ++ + G E +V EY+ G L + + A V Sbjct 292 INEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVV--TETCMDEAQIAAVC 349 Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREE 771 ++ AL +L ++H ++ N+LL G +KL+D G R Sbjct 350 RECLQALEFLHANQVIHRDIKSDNVLL-------GMEGSVKLTDFGFCAQITPEQSKRST 402 Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 V W+APE + A +D W G +E+ +GE P + +P + Sbjct 403 MVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNG 459 Query 832 RL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 PE P ++CL + +R S + +L+ Sbjct 460 TPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPF 499 >sp|C0LGH3|Y5614_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g56140 OS=Arabidopsis thaliana OX=3702 GN=At1g56140 PE=2 SV=2 Length=1033 Score = 233 bits (593), Expect = 2e-61, Method: Composition-based stats. Identities = 76/317 (24%), Positives = 124/317 (39%), Gaps = 18/317 (6%) Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920 I + R + V P + + LGEG FG V Sbjct 657 IIRKRRKRYTDDEEILSMDVKPYTFTYSELKSATQDFDPSNKLGEGGFGPVYKG-----K 711 Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 G VAVK L Q + + EI + + H +++K GCC + + LV EY Sbjct 712 LNDGREVAVKLLSVG-SRQGKGQFVAEIVAISAVQHRNLVKLYGCCYEGEHR--LLVYEY 768 Query 981 VPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDND 1034 +P GSL L + + + G+ YLH + +HRD+ A N+LLD+ Sbjct 769 LPNGSLDQALFGEKTLHLDWSTRYEICLGVARGLVYLHEEARLRIVHRDVKASNILLDSK 828 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 + K+ DFGLAK + + R G + + APE +DV++FGV EL Sbjct 829 LVPKVSDFGLAKLYDDKKTHISTRVAG--TIGYLAPEYAMRGHLTEKTDVYAFGVVALEL 886 Query 1095 LTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 ++ S ++ + L+ A R EL++ + + + C + Sbjct 887 VSGRPNSDENLEDEKRYLLEWAWNLHEKGREVELIDHQLT-EFNMEEGKRMIGIALLCTQ 945 Query 1154 TEASFRPTFENLIPILK 1170 T + RP ++ +L Sbjct 946 TSHALRPPMSRVVAMLS 962 Score = 229 bits (583), Expect = 3e-60, Method: Composition-based stats. Identities = 63/276 (23%), Positives = 102/276 (37%), Gaps = 47/276 (17%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 P T S+L + ++ + LG+G VY+G+L Sbjct 676 VKPYTFTYSEL---KSATQDFDPSNKLGEGGFGPVYKGKLNDGR---------------- 716 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 V +K+L F +S V H +L ++G C G ++V E Sbjct 717 ---------EVAVKLLSVGSRQGKGQFVAEIVAISAVQHRNLVKLYGCCYEGEHRLLVYE 767 Query 689 YVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744 Y+ +G LD L E+ H+ + + + +A L YL + +VH +V NILL Sbjct 768 YLPNGSLDQALFGEKTLHLDWSTRYEICLGVARGLVYLHEEARLRIVHRDVKASNILLDS 827 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWG 799 + K+SD G+ ++ + I +LAPE G L+ D + Sbjct 828 KLVP-------KVSDFGLAKLYDDKKTHISTRVAGTIGYLAPEYAMRG--HLTEKTDVYA 878 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 FG LE+ G EK + + L E Sbjct 879 FGVVALELVS-GRPNSDENLEDEKRYLLEWAWNLHE 913 >sp|Q875L0|HOG1_CRYPA Mitogen-activated protein kinase HOG1 OS=Cryphonectria parasitica OX=5116 GN=HOG1 PE=1 SV=1 Length=358 Score = 218 bits (554), Expect = 2e-61, Method: Composition-based stats. Identities = 66/283 (23%), Positives = 110/283 (39%), Gaps = 29/283 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VA+K + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SARDQLTNQNVAIKKIMKPFSTPVLAKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L + ER P + + L++ + R T + + Sbjct 252 SLPKRERQPLASKFKNADEQAVDLLERMLVFDPKKRITASDAL 294 Score = 132 bits (331), Expect = 7e-32, Method: Composition-based stats. Identities = 37/231 (16%), Positives = 75/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E D + M + RD+ V +K ++ P +A Y Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAIKKIMKPFSTPVLAKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|H2KZW3|M3K20_CAEEL Mitogen-activated protein kinase kinase kinase zak-1 OS=Caenorhabditis elegans OX=6239 GN=zak-1 PE=2 SV=1 Length=745 Score = 228 bits (582), Expect = 2e-61, Method: Composition-based stats. Identities = 74/285 (26%), Positives = 121/285 (42%), Gaps = 45/285 (16%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V + DG+ +A+K + ++E +IL + H++II++ Sbjct 37 IGVGTFGAVFSGNWT-LPDGSQRTIALKKVFV---------LEKEAEILSKIRHKNIIQF 86 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----------SIGLAQLLLFAQQICEGMA 1012 G C+ G +V EY GSL D++ ++ +A QI G+ Sbjct 87 YGICKATG-NDFFIVTEYAEKGSLYDFIHSEESQSFASSSGGNSFDVVVKWASQIASGIQ 145 Query 1013 YLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH IHRDL ++NV+LD + + KI DFG +K + + W + Sbjct 146 YLHYDAVDTIIHRDLKSKNVVLDKNLVCKICDFGTSKDL----THSCTAPSWGGTAAWMS 201 Query 1070 PE-CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE L+ A+DVWS+GV L+E+L+ + + R+ ++ Sbjct 202 PEMILQSEGLTTATDVWSYGVVLWEILSK---------------EVPYKDYSEFRIFTMI 246 Query 1129 ER-GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + G L P CP + LM NCW+ R + L + Sbjct 247 TQSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQIQGELNRL 291 Score = 199 bits (507), Expect = 6e-52, Method: Composition-based stats. Identities = 64/321 (20%), Positives = 111/321 (35%), Gaps = 56/321 (17%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 F + + +I H+G GT V+ G + G + + Sbjct 23 FPDIQRDDIQVGDHIGVGTFGAVFSGNWTLPD---------------------GSQRTIA 61 Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC-VRGPENIMVTEYVEHGPLDVWL 699 LK + + A ++S++ H ++ +G+C G + +VTEY E G L ++ Sbjct 62 LKKV--------FVLEKEAEILSKIRHKNIIQFYGICKATGNDFFIVTEYAEKGSLYDFI 113 Query 700 RRERGHV--------PMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLA 748 E + A Q+AS + YL ++H ++ +N++L + Sbjct 114 HSEESQSFASSSGGNSFDVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLDK---- 169 Query 749 EGTSPFIKLSDPGVGLGALSREER---VERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + K+ D G W++PE + + L+TA D W +G L Sbjct 170 ---NLVCKICDFGTSKDLTHSCTAPSWGGTAAWMSPEMILQ-SEGLTTATDVWSYGVVLW 225 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHR---LPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 EI E P + S + +P L L S C P R + R I Sbjct 226 EILSK-EVPYKDYSEFRIFTMITQSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQI 284 Query 863 LRDLTRLQPHNLADVLTVNPD 883 +L RL + Sbjct 285 QGELNRLAGNQKVMDECEKFM 305 >sp|Q0JEU6|LERK3_ORYSJ G-type lectin S-receptor-like serine/threonine-protein kinase LECRK3 OS=Oryza sativa subsp. japonica OX=39947 GN=LECRK3 PE=3 SV=2 Length=811 Score = 229 bits (585), Expect = 2e-61, Method: Composition-based stats. Identities = 70/288 (24%), Positives = 117/288 (41%), Gaps = 14/288 (5%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G G V D G +AVK ++ + + + E+ + +H ++++ Sbjct 527 LGTGASGVVYKGQLQ---DEFGTNIAVKKIEK-LQQEAQKEFLVEVQTIGQTFHRNLVRL 582 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH---AQH 1018 G C + E+ LV E++ GSL +L + + + A + G+ YLH + Sbjct 583 LGFCNEGTER--LLVYEFMSNGSLNTFLFSDTHPHWSLRVQVALGVARGLLYLHEECNKQ 640 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IH D+ +N+LLD++ + KI DFGLAK +P + + APE K Sbjct 641 IIHCDMKPQNILLDDNFVAKISDFGLAKLLPVNQT--QTNTGIRGTRGYVAPEWFKNIGI 698 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPR 1136 DV+SFGV L EL+ + + + L A R+ L+ + Sbjct 699 TSKVDVYSFGVILLELVCCRKNVELEVLDEEQTILTYWANDCYKCGRIDLLVAGDDEAIF 758 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 K + C + E S RPT + +L + PS + Sbjct 759 NIKKVERFVAVALWCLQEEPSMRPTMLKVTQMLDGAVQIPTPPDPSSY 806 Score = 209 bits (533), Expect = 6e-55, Method: Composition-based stats. Identities = 77/408 (19%), Positives = 140/408 (34%), Gaps = 75/408 (18%) Query 486 TVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCF 545 TV + S+ ++D + + G F S L L ++ G C Sbjct 430 TVLIKVPRSTNSPSVFSSGSSKWKEDQKYWILGSSLLFGS-SVLVNFLLISVMLFGTYCS 488 Query 546 SLRR--CCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603 R L QP S L P+ S+L +E+ LG G V Sbjct 489 ITSRKKTQLSQPSNNSGL--------PPKIFTYSELEKATGGFQEV-----LGTGASGVV 535 Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663 Y+G+L+ E + + +K ++ + F + Sbjct 536 YKGQLQDEFGTN-----------------------IAVKKIEKLQQEAQKEFLVEVQTIG 572 Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723 Q H +L + G C G E ++V E++ +G L+ +L H + ++ VA +A L Sbjct 573 QTFHRNLVRLLGFCNEGTERLLVYEFMSNGSLNTFLF-SDTHPHWSLRVQVALGVARGLL 631 Query 724 YLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ER 775 YL NK ++H ++ +NILL + K+SD G+ + + Sbjct 632 YLHEECNKQIIHCDMKPQNILLD-------DNFVAKISDFGLAKLLPVNQTQTNTGIRGT 684 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 ++APE +++ +D + FG LLE+ + E+ + + Sbjct 685 RGYVAPEWFKNIG--ITSKVDVYSFGVILLELVCCRKNVELEVLDEEQTILTYWANDCYK 742 Query 836 P------------------SCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + + CL EP+ RP+ + + Sbjct 743 CGRIDLLVAGDDEAIFNIKKVERFVAVALWCLQEEPSMRPTMLKVTQM 790 >sp|P79750|CSF11_TAKRU Macrophage colony-stimulating factor 1 receptor 1 OS=Takifugu rubripes OX=31033 GN=csf1r1 PE=3 SV=1 Length=975 Score = 232 bits (591), Expect = 2e-61, Method: Composition-based stats. Identities = 92/365 (25%), Positives = 147/365 (40%), Gaps = 88/365 (24%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY--CYDPTNDGTGEMVAVKALKADCGP 938 P ++ F + LK + LG G FGKV + VAVK LKA+ Sbjct 568 PTQLPYNEKWEFPRDKLKLGKVLGAGAFGKVVEATAFGLGEDKDNTLRVAVKMLKANAHS 627 Query 939 QHRSGWKQEIDILRTL-YHEHIIKYKGCCE----------------------DQGEKSLQ 975 R E+ IL L +H++I+ G C + E + Sbjct 628 DEREALMSELKILSHLGHHQNIVNLLGACTYGGPVLVITEYCSLGDLLNFLRQKAETFVN 687 Query 976 LVM---EYVPLGSLRDYLPRHS-------------------------------------- 994 LVM E + + + Sbjct 688 LVMNIPEIMENSNDYKNICNQKWYIRSDSGISSTSSSTYLEMRPSQQSHIEASGRKSLCE 747 Query 995 ------IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + + LL F+ Q+ +G+ +L +++ IHRD+AARNVLL + R+ KI DFGLA+ + Sbjct 748 DNGDWPLDIDDLLRFSLQVAQGLDFLASRNCIHRDVAARNVLLTDKRVAKICDFGLARDI 807 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 Y V+ + PV W APE + + + SDVWS+G+ L+E+ + S Sbjct 808 MNDSNYV-VKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGKS-------- 858 Query 1109 LELIGIAQGQMTVL-RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 M V R ++++RG ++ +PD E+Y +MK CW E + RPTF + Sbjct 859 ------PYPSMAVDSRFYKMVKRGYQMSQPDFALPEIYMIMKMCWNLEPTERPTFSMISQ 912 Query 1168 ILKTV 1172 ++ + Sbjct 913 MINRL 917 Score = 189 bits (480), Expect = 1e-47, Method: Composition-based stats. Identities = 66/413 (16%), Positives = 122/413 (30%), Gaps = 107/413 (26%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + ++ LG G V + G D Sbjct 568 PTQLPYNEKWEFPRDKLKLGKVLGAGAFGKV------------------VEATAFGLGED 609 Query 633 RGQELRVVLKVLDPS-HHDIALAFYETASLMSQV-SHTHLAFVHG-------------VC 677 + LRV +K+L + H D A ++S + H ++ + G C Sbjct 610 KDNTLRVAVKMLKANAHSDEREALMSELKILSHLGHHQNIVNLLGACTYGGPVLVITEYC 669 Query 678 VRGPENI-----------MVT---EYVEHG------------------------------ 693 G +V E +E+ Sbjct 670 SLGDLLNFLRQKAETFVNLVMNIPEIMENSNDYKNICNQKWYIRSDSGISSTSSSTYLEM 729 Query 694 --PLDVWL----------RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 + + + + + Q+A L +L ++N +H +V RN+L Sbjct 730 RPSQQSHIEASGRKSLCEDNGDWPLDIDDLLRFSLQVAQGLDFLASRNCIHRDVAARNVL 789 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAM 795 L K+ D G+ ++ V + + W+APE + + Sbjct 790 LTDK-------RVAKICDFGLARDIMNDSNYVVKGNARLPVKWMAPESIFDCV--YTVQS 840 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR---QHRLPEPSCPQLATLTSQCLTYE 852 D W +G L EI G++P S + + + + Q P+ + P++ + C E Sbjct 841 DVWSYGILLWEIFSLGKSPYPSMAVDSRFYKMVKRGYQMSQPDFALPEIYMIMKMCWNLE 900 Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 PT+RP+F I + + RL + + K D Sbjct 901 PTERPTFSMISQMINRLLGGQDEQEKLIYRNVQPEQVAEGEACDEPKRYDPPC 953 >sp|Q9QUK0|CDKL2_MOUSE Cyclin-dependent kinase-like 2 OS=Mus musculus OX=10090 GN=Cdkl2 PE=2 SV=1 Length=568 Score = 224 bits (570), Expect = 2e-61, Method: Composition-based stats. Identities = 74/284 (26%), Positives = 122/284 (43%), Gaps = 29/284 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG +G V N +G +VA+K L++D + +EI +L+ L HE+++ Sbjct 10 VGEGSYGMVM----KCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 C + +K LV E+V L D L + + + + QI G+ + H+ + I Sbjct 66 LLEVC--KKKKRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFCHSHNII 123 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFY 1079 HRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L K+ Sbjct 124 HRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVKYG 180 Query 1080 YASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 A D+W+ G + E+L +S + +G + L + G RL Sbjct 181 KAVDIWAIGCLVIEMLMGQPLFPGESDIDQLHHIMTCLGNLIPRHQELFYKNPVFAGVRL 240 Query 1135 P------------RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 P R K P V L K C + RP +L+ Sbjct 241 PEVKDAEAEPLESRYPKLPEAVISLAKKCLHIDPDKRPFCADLL 284 Score = 161 bits (408), Expect = 3e-40, Method: Composition-based stats. Identities = 64/402 (16%), Positives = 124/402 (31%), Gaps = 80/402 (20%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-L 644 ++ L +G+G+ V + R + G V +K L Sbjct 1 MEKYENLGLVGEGSYGMVMKCRNKDSGR------------------------IVAIKKFL 36 Query 645 DPSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + + L+ Q+ H +L + VC + +V E+V+H LD L+ Sbjct 37 ESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDD-LKLFP 95 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + Q+ + + + + N++H ++ NIL+++ G+ +KL D G Sbjct 96 NGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFA 148 Query 764 LGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + + V + APE L G A+D W G ++E+ Sbjct 149 RTLAAPGEVYTDYVATRWYRAPELLV-GDVKYGKAVDIWAIGCLVIEMLMGQPLFPGESD 207 Query 820 PSEKEHFY-------------------QRQHRLPEPS--------------CPQLATLTS 846 + H RLPE + +L Sbjct 208 IDQLHHIMTCLGNLIPRHQELFYKNPVFAGVRLPEVKDAEAEPLESRYPKLPEAVISLAK 267 Query 847 QCLTYEPTQRP-SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 +CL +P +RP + D ++ + + + + + Sbjct 268 KCLHIDPDKRPFCADLLRHDFFQMDGFAERFSQELQLKIEKDARNNSLPKKSQNRKKEKD 327 Query 906 GHFGK------VSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 G+ V DP + ++ VK K D + Sbjct 328 DALGEERKTLVVQDTNADPKIKDS-KVFKVKGSKIDVEKMEK 368 >sp|P06782|SNF1_YEAST Carbon catabolite-derepressing protein kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SNF1 PE=1 SV=1 Length=633 Score = 226 bits (575), Expect = 2e-61, Method: Composition-based stats. Identities = 75/279 (27%), Positives = 114/279 (41%), Gaps = 31/279 (11%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG--WKQEIDI 950 H + ++ LGEG FGKV L + TG+ VA+K + + ++EI Sbjct 51 HIGNYQIVKTLGEGSFGKVKLAY----HTTTGQKVALKIINKKVLAKSDMQGRIEREISY 106 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICE 1009 LR L H HIIK + + E + +V+EY L DY+ R + + F QQI Sbjct 107 LRLLRHPHIIKLYDVIKSKDE--IIMVIEYAGN-ELFDYIVQRDKMSEQEARRFFQQIIS 163 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + Y H +HRDL N+LLD VKI DFGL+ + +G+ ++ SP + A Sbjct 164 AVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGN---FLKTSCGSPN-YAA 219 Query 1070 PECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE + + DVWS GV LY +L ++ L + + Sbjct 220 PEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDE---------------SIPVLFKNI 264 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 G P L+K R + ++ Sbjct 265 SNGV-YTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQ 302 Score = 178 bits (451), Expect = 2e-45, Method: Composition-based stats. Identities = 54/287 (19%), Positives = 95/287 (33%), Gaps = 40/287 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + LG+G+ V G +V LK+++ Sbjct 54 NYQIVKTLGEGSFGKVKLAYHTTTGQ------------------------KVALKIINKK 89 Query 648 ---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D+ S + + H H+ ++ V E IMV EY + L ++ +R Sbjct 90 VLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGN-ELFDYI-VQRD 147 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + QQ+ SA+ Y +VH ++ N+LL +K++D G+ Sbjct 148 KMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDE-------HLNVKIADFGLSN 200 Query 765 GALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + + APE + G + +D W G L + P Sbjct 201 IMTDGNFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYVMLCRRLPFDDESIPV 259 Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 ++ + LP+ P A L + L P R S I++D Sbjct 260 LFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWF 306 >sp|Q9M342|WAKLP_ARATH Wall-associated receptor kinase-like 15 OS=Arabidopsis thaliana OX=3702 GN=WAKL15 PE=2 SV=2 Length=639 Score = 226 bits (575), Expect = 2e-61, Method: Composition-based stats. Identities = 75/290 (26%), Positives = 129/290 (44%), Gaps = 30/290 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG+V N G VAVK K + E+ IL + H++++K Sbjct 360 LGFGGFGEVFKG-----NLDDGTTVAVKRAKLG-NEKSIYQIVNEVQILCQVSHKNLVKL 413 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------IGLAQLLLFAQQICEGMAY 1013 GCC + + LV E+VP G+L +++ + L + L+ A Q +G+ Y Sbjct 414 LGCCIEL--EMPVLVYEFVPNGTLFEHIYGGGGGGGGLYDHLPLRRRLMIAHQTAQGLDY 471 Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 LH+ HRD+ + N+LLD + VK+ DFGL++ + V + + P Sbjct 472 LHSSSSPPIYHRDVKSSNILLDENLDVKVADFGLSRLGVSDVSH--VTTCAQGTLGYLDP 529 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E ++ SDV+SFGV L+ELLT + + + + L+ + + RL ++++ Sbjct 530 EYYLNFQLTDKSDVYSFGVVLFELLTCKKAIDFNREEEDVNLVVFVRKALKEGRLMDVID 589 Query 1130 RGERLPRPDKCPCEVYH---LMKNCWETEASFRPTF----ENLIPILKTV 1172 + +K + L + C + RPT + + IL + Sbjct 590 PVIGIGATEKEIESMKALGVLAELCVKETRQCRPTMQVAAKEIENILHGI 639 Score = 207 bits (526), Expect = 4e-55, Method: Composition-based stats. Identities = 53/277 (19%), Positives = 97/277 (35%), Gaps = 54/277 (19%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + + LG G V++G L V +K Sbjct 350 ATDNFAKSNLLGFGGFGEVFKGNLDDG-------------------------TTVAVKRA 384 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER- 703 + ++ QVSH +L + G C+ ++V E+V +G L + Sbjct 385 KLGNEKSIYQIVNEVQILCQVSHKNLVKLLGCCIELEMPVLVYEFVPNGTLFEHIYGGGG 444 Query 704 ------GHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPF 754 H+P+ ++++A Q A L YL + + + H +V NILL + Sbjct 445 GGGGLYDHLPLRRRLMIAHQTAQGLDYLHSSSSPPIYHRDVKSSNILLDE-------NLD 497 Query 755 IKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 +K++D G+ +S V + +L PE L+ D + FG L E+ Sbjct 498 VKVADFGLSRLGVSDVSHVTTCAQGTLGYLDPEYYLN--FQLTDKSDVYSFGVVLFELLT 555 Query 810 DGEAPLQSRSPSEKEHFYQ-----RQHRLPEPSCPQL 841 +A +R + ++ RL + P + Sbjct 556 CKKAIDFNREEEDVNLVVFVRKALKEGRLMDVIDPVI 592 >sp|Q3TZA2|CDKL4_MOUSE Cyclin-dependent kinase-like 4 OS=Mus musculus OX=10090 GN=Cdkl4 PE=2 SV=1 Length=342 Score = 217 bits (552), Expect = 2e-61, Method: Composition-based stats. Identities = 68/301 (23%), Positives = 125/301 (42%), Gaps = 34/301 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960 +GEG +G V + N +G++VA+K ++++ R +EI +L+ L H +++ Sbjct 9 KIGEGSYGVV----FKCRNKSSGQVVAIKKFVESEDDRVVRKIALREIRMLKQLKHPNLV 64 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQH 1018 + + + LV EY +L + L R+ G++ + Q + + + H + Sbjct 65 NLIEVFRRK--RKMHLVFEYCDH-TLLNELERNPNGVSDGVIKSVLWQTLQALNFCHKHN 121 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEYK 1077 IHRD+ N+L+ ++KI DFG A+ + G Y D + ++ APE L + K Sbjct 122 CIHRDVKPENILITKQGMIKICDFGFARILIPGDAY----TDYVATRWYRAPELLVGDTK 177 Query 1078 FYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + DVW+ G ELLT S + +G + + + RG Sbjct 178 YGSSVDVWAVGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFRSNQFFRGI 237 Query 1133 RLPRPDKC-----------PCEVYHLMKNCWETEASFRPTFENLIP--ILKTVHEKYQGQ 1179 +P P+ P + MK C + R T L+ ++ E + Sbjct 238 SIPEPEDMETLEEKFSNVQPVAL-SFMKGCLKMNPDERLTCAQLLDSAYFESFQEDQMKR 296 Query 1180 A 1180 Sbjct 297 K 297 Score = 162 bits (411), Expect = 1e-42, Method: Composition-based stats. Identities = 52/260 (20%), Positives = 93/260 (36%), Gaps = 41/260 (16%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ +L+ +G+G+ V++ R + G V +K Sbjct 1 MEKYEKLAKIGEGSYGVVFKCRNKSSGQ------------------------VVAIKKFV 36 Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 S D + ++ Q+ H +L + V R + +V EY +H L L R Sbjct 37 ESEDDRVVRKIALREIRMLKQLKHPNLVNLIEVFRRKRKMHLVFEYCDH-TLLNELERNP 95 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 V V Q AL++ N +H +V NIL+ + G+ IK+ D G Sbjct 96 NGVSDGVIKSVLWQTLQALNFCHKHNCIHRDVKPENILITKQGM-------IKICDFGFA 148 Query 764 L---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 + + V + APE L G +++D W G E+ G+ +S Sbjct 149 RILIPGDAYTDYVATRWYRAPELLV-GDTKYGSSVDVWAVGCVFAELL-TGQPLWPGKSD 206 Query 821 SEKEHFYQR--QHRLPEPSC 838 ++ + R +P Sbjct 207 VDQLYLIIRTLGKLIPRHQS 226 >sp|Q9M020|LRK63_ARATH Lectin-domain containing receptor kinase VI.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK63 PE=2 SV=1 Length=688 Score = 227 bits (578), Expect = 2e-61, Method: Composition-based stats. Identities = 68/301 (23%), Positives = 121/301 (40%), Gaps = 22/301 (7%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 +P K+ R +G G FG V + + + +AVK + + Q Sbjct 344 NHPHRLRYKDLYAATDGFKENRIVGTGGFGTVFRGNL---SSPSSDQIAVKKITPN-SMQ 399 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----- 994 + EI+ L L H++++ +G C+ + + L L+ +Y+P GSL L Sbjct 400 GVREFIAEIESLGRLRHKNLVNLQGWCKQKND--LLLIYDYIPNGSLDSLLYSRPRQSGV 457 Query 995 -IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 + A+ I G+ YLH + IHRD+ NVL+++D ++GDFGLA+ Sbjct 458 VLSWNARFKIAKGIASGLLYLHEEWEKVVIHRDIKPSNVLIEDDMNPRLGDFGLARLYER 517 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 G + + + APE + K ASDV++FGV L E+++ + S Sbjct 518 GSQSNTT--VVVGTIGYMAPELARNGKSSSASDVFAFGVLLLEIVSGRRPTDS---GTFF 572 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM-KNCWETEASFRPTFENLIPIL 1169 L + ++ D + ++ C + RP+ ++ L Sbjct 573 LADWVMELHARGEILHAVDPRLGFGY-DGVEARLALVVGLLCCHQRPTSRPSMRTVLRYL 631 Query 1170 K 1170 Sbjct 632 N 632 Score = 210 bits (535), Expect = 8e-56, Method: Composition-based stats. Identities = 61/306 (20%), Positives = 104/306 (34%), Gaps = 57/306 (19%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + +G G V+ G L S ++ +K + Sbjct 357 ATDGFKENRIVGTGGFGTVFRGNLSSPSSD-----------------------QIAVKKI 393 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 P+ F + ++ H +L + G C + + +++ +Y+ +G LD L Sbjct 394 TPNSMQGVREFIAEIESLGRLRHKNLVNLQGWCKQKNDLLLIYDYIPNGSLDSLLYSRPR 453 Query 705 H----VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + + +A+ +AS L YL K ++H ++ N+L+ +L Sbjct 454 QSGVVLSWNARFKIAKGIASGLLYLHEEWEKVVIHRDIKPSNVLI-------EDDMNPRL 506 Query 758 SDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 D G+ + V I ++APE G + S+A D + FG LLEI Sbjct 507 GDFGLARLYERGSQSNTTVVVGTIGYMAPELARNGKS--SSASDVFAFGVLLLEIVSGRR 564 Query 813 A---------PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLT----SQCLTYEPTQRPSF 859 + E + RL A L C PT RPS Sbjct 565 PTDSGTFFLADWVMELHARGEILHAVDPRLGFGYDGVEARLALVVGLLCCHQRPTSRPSM 624 Query 860 RTILRD 865 RT+LR Sbjct 625 RTVLRY 630 >sp|O65530|PEK14_ARATH Proline-rich receptor-like protein kinase PERK14 OS=Arabidopsis thaliana OX=3702 GN=PERK14 PE=2 SV=1 Length=731 Score = 228 bits (580), Expect = 2e-61, Method: Composition-based stats. Identities = 78/334 (23%), Positives = 131/334 (39%), Gaps = 28/334 (8%) Query 853 PTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVS 912 P + + +++A +++ + + + LGEG FG V Sbjct 345 PPPIHAKYISSGGCDTKENNSVAKNISMPSGMFSYEELSKATGGFSEENLLGEGGFGYVH 404 Query 913 LYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972 G VAVK LK Q ++ E+D + ++H+H++ G C + ++ Sbjct 405 KGVLK-----NGTEVAVKQLKIG-SYQGEREFQAEVDTISRVHHKHLVSLVGYCVNGDKR 458 Query 973 SLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAA 1026 LV E+VP +L +L + + L A +G+AYLH IHRD+ A Sbjct 459 --LLVYEFVPKDTLEFHLHENRGSVLEWEMRLRIAVGAAKGLAYLHEDCSPTIIHRDIKA 516 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYR-VREDGDSPVFWYAPECLKEYKFYYASDVW 1085 N+LLD+ K+ DFGLAK + + + + + APE K SDV+ Sbjct 517 ANILLDSKFEAKVSDFGLAKFFSDTNSSFTHISTRVVGTFGYMAPEYASSGKVTDKSDVY 576 Query 1086 SFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMT--------VLRLTELLERGERLPR 1136 SFGV L EL+T S + L+ A+ +T + LE+ + Sbjct 577 SFGVVLLELITGRPSIFAKDSSTNQSLVDWARPLLTKAISGESFDFLVDSRLEKNYDTTQ 636 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 ++ A RP ++ L+ Sbjct 637 MANMAACAAACIRQ----SAWLRPRMSQVVRALE 666 Score = 223 bits (568), Expect = 9e-60, Method: Composition-based stats. Identities = 56/288 (19%), Positives = 101/288 (35%), Gaps = 48/288 (17%) Query 565 RGARASPRTLNLSQLSFHRVDQKE--ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 + A ++ S+ + + ++ + LG+G V++G L+ Sbjct 363 NNSVAKNISMPSGMFSYEELSKATGGFSEENLLGEGGFGYVHKGVLKNG----------- 411 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 V +K L + F +S+V H HL + G CV G + Sbjct 412 --------------TEVAVKQLKIGSYQGEREFQAEVDTISRVHHKHLVSLVGYCVNGDK 457 Query 683 NIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKN---LVHGNVCGR 738 ++V E+V L+ L RG + ++ +A A L+YL ++H ++ Sbjct 458 RLLVYEFVPKDTLEFHLHENRGSVLEWEMRLRIAVGAAKGLAYLHEDCSPTIIHRDIKAA 517 Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSR--------EERVERIPWLAPECLPGGANS 790 NILL A K+SD G+ V ++APE G Sbjct 518 NILLDSKFEA-------KVSDFGLAKFFSDTNSSFTHISTRVVGTFGYMAPEYASSG--K 568 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838 ++ D + FG LLE+ + S + + + L + Sbjct 569 VTDKSDVYSFGVVLLELITGRPSIFAKDSSTNQSLVDWARPLLTKAIS 616 >sp|A0A8I3S724|AURKA_CANLF Aurora kinase A OS=Canis lupus familiaris OX=9615 GN=AURKA PE=1 SV=1 Length=405 Score = 219 bits (557), Expect = 2e-61, Method: Composition-based stats. Identities = 65/290 (22%), Positives = 115/290 (40%), Gaps = 30/290 (10%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQ 939 + S + + R LG+G FG V L + ++A+K L KA Sbjct 118 KQKNEESKKRQWALEDFEIGRPLGKGKFGNVYL----AREKQSKFILAIKVLFKAQLEKA 173 Query 940 HRS-GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGL 997 ++E++I L H +I++ G D + L++EY PLG++ L + Sbjct 174 GVEHQLRREVEIQSHLRHPNILRLYGYFHDAT--RVYLILEYAPLGAVYRELQKLSKFDE 231 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + + ++ + ++Y H++ IHRD+ N+LL + +KI DFG + P Sbjct 232 QRTATYITELADALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSR----- 286 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 R + + PE ++ D+WS GV YE L ++ Sbjct 287 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA-------------- 332 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 T + + R E PD P L+ + S RPT ++++ Sbjct 333 -STYQETYKRISRVE-FTFPDFVPEGARDLISRLLKHNPSQRPTLKDVLE 380 Score = 187 bits (474), Expect = 3e-50, Method: Composition-based stats. Identities = 59/327 (18%), Positives = 116/327 (35%), Gaps = 48/327 (15%) Query 549 RCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRL 608 + PG S + + L ++ LG+G NVY Sbjct 101 QPSSSAPGNNSEKELATKQKNEESKKRQWAL-------EDFEIGRPLGKGKFGNVYLA-- 151 Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD---IALAFYETASLMSQV 665 R++ + + +KVL + + + + S + Sbjct 152 ----------------------REKQSKFILAIKVLFKAQLEKAGVEHQLRREVEIQSHL 189 Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL 725 H ++ ++G ++ EY G + L++ +LA ALSY Sbjct 190 RHPNILRLYGYFHDATRVYLILEYAPLGAVYRELQKL-SKFDEQRTATYITELADALSYC 248 Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--REERVERIPWLAPEC 783 +K ++H ++ N+LL G++ +K++D G + A S R + +L PE Sbjct 249 HSKRVIHRDIKPENLLL-------GSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEM 301 Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPSCPQLA 842 + G + +D W G E G+ P ++ + E + + P+ Sbjct 302 IEGRMH--DEKVDLWSLGVLCYEFLV-GKPPFEASTYQETYKRISRVEFTFPDFVPEGAR 358 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRL 869 L S+ L + P+QRP+ + +L + Sbjct 359 DLISRLLKHNPSQRPTLKDVLEHPWIM 385 >sp|Q4R7T5|CDKL2_MACFA Cyclin-dependent kinase-like 2 OS=Macaca fascicularis OX=9541 GN=CDKL2 PE=2 SV=1 Length=570 Score = 224 bits (570), Expect = 2e-61, Method: Composition-based stats. Identities = 75/283 (27%), Positives = 119/283 (42%), Gaps = 27/283 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG +G V N TG +VA+K L++D + +EI +L+ L HE+++ Sbjct 10 VGEGSYGMVV----KCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVN 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 C + +K LV E+V L D L + + + + QI G+ + H+ + I Sbjct 66 LLEVC--KKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNII 123 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFY 1079 HRD+ N+L+ +VK+ DFG A+ + E Y D + ++ APE L K+ Sbjct 124 HRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVY---TDYVATRWYRAPELLVGDVKYG 180 Query 1080 YASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 A DVW+ G + E+ DS + +G + L + G RL Sbjct 181 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFYKNPVFAGVRL 240 Query 1135 P----------RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P R K V L K C + RP L+ Sbjct 241 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCSELLH 283 Score = 161 bits (407), Expect = 3e-40, Method: Composition-based stats. Identities = 56/320 (18%), Positives = 101/320 (32%), Gaps = 70/320 (22%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-L 644 ++ L +G+G+ V V R++ V +K L Sbjct 1 MEKYENLGLVGEGSYGMV------------------------VKCRNKDTGRIVAIKKFL 36 Query 645 DPSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + + L+ Q+ H +L + VC + +V E+V+H LD L Sbjct 37 ESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDD-LELFP 95 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + Q+ + + + + N++H ++ NIL+++ G+ +KL D G Sbjct 96 NGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGV-------VKLCDFGFA 148 Query 764 LGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + + V + APE L G A+D W G + E+ Sbjct 149 RTLAAPGEVYTDYVATRWYRAPELLV-GDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSD 207 Query 820 PSEKEHFYQ-------------------RQHRLPEPS------------CPQLATLTSQC 848 + H RLPE + L +C Sbjct 208 IDQLYHIMMCLGNLIPRHQELFYKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKC 267 Query 849 LTYEPTQRPSFRTILRDLTR 868 L +P +RP +L Sbjct 268 LHIDPDKRPFCSELLHHDFF 287 >sp|A0A509AHB6|CDPK1_PLABA Calcium-dependent protein kinase 1 OS=Plasmodium berghei (strain Anka) OX=5823 GN=CDPK1 PE=1 SV=1 Length=523 Score = 223 bits (567), Expect = 2e-61, Method: Composition-based stats. Identities = 77/290 (27%), Positives = 116/290 (40%), Gaps = 45/290 (16%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR------------SGW 944 K+R LG G +G+V L + A+K +K + R Sbjct 57 YFKVRKLGSGAYGEVLLCKEKNGHSEK----AIKVIKKSQFDKGRYSDDNKNIEKFHEEI 112 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLF 1003 EI +L++L H +IIK ED+ K LV E+ G L + + RH Sbjct 113 YNEISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAANI 170 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVRED 1060 +QI G+ YLH + +HRD+ N+LL+N +KI DFGL+ + Y++R D Sbjct 171 MKQILSGICYLHKHNIVHRDIKPENILLENKNSLLNIKIVDFGLSSFFSKD---YKLR-D 226 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 ++ APE LK K+ DVWS GV +Y LL G Sbjct 227 RLGTAYYIAPEVLK-KKYNEKCDVWSCGVIMYILLCGYPPF---------------GGQN 270 Query 1121 VLRLTELLERG-ERLPRPD--KCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + +E+G D E L+K + + R T E + Sbjct 271 DQDIIKKVEKGKYYFDFNDWKNISDEAKELIKLMLTYDYNKRCTAEEALN 320 Score = 183 bits (464), Expect = 6e-48, Method: Composition-based stats. Identities = 51/289 (18%), Positives = 96/289 (33%), Gaps = 28/289 (10%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + ++ LG G V + + + K+ + GR + Sbjct 55 ESYFKVRKLGSGAYGEVL--LCKEKNGHSEKAIKVIKKSQFDKGRYSDD---------NK 103 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 + Y SL+ + H ++ + V +VTE+ E G L + R Sbjct 104 NIEKFHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQII-NRHKF 162 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--- 763 + +Q+ S + YL N+VH ++ NILL + + IK+ D G+ Sbjct 163 DECDAANIMKQILSGICYLHKHNIVHRDIKPENILLEN----KNSLLNIKIVDFGLSSFF 218 Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 +R+ ++APE L + D W G + I G P ++ + Sbjct 219 SKDYKLRDRLGTAYYIAPEVL---KKKYNEKCDVWSCGVIMY-ILLCGYPPFGGQNDQDI 274 Query 824 EHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 ++ + + L LTY+ +R + L Sbjct 275 IKKVEKGKYYFDFNDWKNISDEAKELIKLMLTYDYNKRCTAEEALNSRW 323 >sp|Q0D4B2|CIPKL_ORYSJ CBL-interacting protein kinase 21 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK21 PE=2 SV=2 Length=525 Score = 223 bits (567), Expect = 2e-61, Method: Composition-based stats. Identities = 69/272 (25%), Positives = 112/272 (41%), Gaps = 27/272 (10%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEID 949 + R LGEGHFGKV L + TG A+K L + K+EI Sbjct 82 MRMGKYEMGRALGEGHFGKVKL----ARHADTGAAFAIKILDRQRILAMKIDEQIKREIA 137 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQIC 1008 L+ L H ++++ + + + +V+EYV G L D + + + + QQ+ Sbjct 138 TLKLLKHPNVVRLHEVSASKTK--IYMVLEYVNGGELFDKIALKGKLSEKEGRKLFQQLM 195 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 + ++Y H + HRDL NVL+D +K+ DFGL+ + + SP + Sbjct 196 DAVSYCHEKGVYHRDLKPENVLVDAKGNIKVSDFGLSALPQNQRKDGLLHTTCGSPN-YI 254 Query 1069 APECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE L + + SD+WS GV LY +LT Q TV+ ++ Sbjct 255 APEVLLNRGYDGSLSDIWSCGVILYVMLTGNLPFDD--------------QNTVVLYQKI 300 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 L+ R P +++ + R Sbjct 301 LKGDAR--IPKWLSPGAQDILRKILDPNPITR 330 Score = 178 bits (451), Expect = 3e-46, Method: Composition-based stats. Identities = 57/319 (18%), Positives = 98/319 (31%), Gaps = 42/319 (13%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + LG+G V R G+ +K+LD Sbjct 86 KYEMGRALGEGHFGKVKLARHADTGAAF------------------------AIKILDRQ 121 Query 648 H---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 I + + + H ++ +H V + MV EYV G L + +G Sbjct 122 RILAMKIDEQIKREIATLKLLKHPNVVRLHEVSASKTKIYMVLEYVNGGELFDKI-ALKG 180 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + QQL A+SY K + H ++ N+L+ G IK+SD G+ Sbjct 181 KLSEKEGRKLFQQLMDAVSYCHEKGVYHRDLKPENVLVDAKG-------NIKVSDFGLSA 233 Query 765 GALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 ++ ++APE L + D W G L + Sbjct 234 LPQNQRKDGLLHTTCGSPNYIAPEVLLNRGYD-GSLSDIWSCGVILYVMLTGNLPFDDQN 292 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + + + R+P+ P + + L P R I Q + A Sbjct 293 TVVLYQKILKGDARIPKWLSPGAQDILRKILDPNPITRLDITGIRAHEWFRQDYTPAMPF 352 Query 879 TVNPDSPASDPTVFHKRYL 897 + D+ SD + Sbjct 353 DDDDDNNISDGNLHMTENQ 371 >sp|Q75Q66|HOG1_COLOR Mitogen-activated protein kinase HOG1 OS=Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422) OX=1213857 GN=HOG1 PE=3 SV=1 Length=357 Score = 217 bits (553), Expect = 2e-61, Method: Composition-based stats. Identities = 66/284 (23%), Positives = 108/284 (38%), Gaps = 29/284 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VAVK + K P +E+ +L+ L HE++ Sbjct 24 QPVGMGAFGLVC----SARDQLTNQNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENV 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L + ER P + L++ + R T + Sbjct 252 SLPKRERQPLKNKFKNADPSAIDLLERMLVFDPKKRITATEALS 295 Score = 130 bits (327), Expect = 2e-31, Method: Composition-based stats. Identities = 36/213 (17%), Positives = 70/213 (33%), Gaps = 18/213 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E D + M + RD+ V +K ++ P +A Y Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAVKKIMKPFSTPVLAKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + APE + +D W G E+ Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML 208 >sp|Q7RAH3|CDPK1_PLAYO Calcium-dependent protein kinase 1 OS=Plasmodium yoelii yoelii OX=73239 GN=CDPK1 PE=3 SV=3 Length=535 Score = 223 bits (567), Expect = 2e-61, Method: Composition-based stats. Identities = 77/290 (27%), Positives = 116/290 (40%), Gaps = 45/290 (16%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR------------SGW 944 K+R LG G +G+V L + A+K +K + R Sbjct 57 YFKVRKLGSGAYGEVLLCKEKNGHSEK----AIKVIKKSQFDKGRYNDDNKNIEKFHEEI 112 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLF 1003 EI +L++L H +IIK ED+ K LV E+ G L + + RH Sbjct 113 YNEISLLKSLDHPNIIKLFDVFEDK--KYFYLVTEFYEGGELFEQIINRHKFDECDAANI 170 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDND---RLVKIGDFGLAKAVPEGHEYYRVRED 1060 +QI G+ YLH + +HRD+ N+LL+N +KI DFGL+ + Y++R D Sbjct 171 MKQILSGICYLHKHNIVHRDIKPENILLENKNSLLNIKIVDFGLSSFFSKD---YKLR-D 226 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 ++ APE LK K+ DVWS GV +Y LL G Sbjct 227 RLGTAYYIAPEVLK-KKYNEKCDVWSCGVIMYILLCGYPPF---------------GGQN 270 Query 1121 VLRLTELLERG-ERLPRPD--KCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + +E+G D E L+K + + R T E + Sbjct 271 DQDIIKKVEKGKYYFDFNDWKNISDEAKELIKLMLTYDYNKRCTAEEALN 320 Score = 183 bits (465), Expect = 6e-48, Method: Composition-based stats. Identities = 51/289 (18%), Positives = 96/289 (33%), Gaps = 28/289 (10%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + ++ LG G V + + + K+ + GR + Sbjct 55 ESYFKVRKLGSGAYGEVL--LCKEKNGHSEKAIKVIKKSQFDKGRYNDD---------NK 103 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 + Y SL+ + H ++ + V +VTE+ E G L + R Sbjct 104 NIEKFHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQII-NRHKF 162 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--- 763 + +Q+ S + YL N+VH ++ NILL + + IK+ D G+ Sbjct 163 DECDAANIMKQILSGICYLHKHNIVHRDIKPENILLEN----KNSLLNIKIVDFGLSSFF 218 Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 +R+ ++APE L + D W G + I G P ++ + Sbjct 219 SKDYKLRDRLGTAYYIAPEVL---KKKYNEKCDVWSCGVIMY-ILLCGYPPFGGQNDQDI 274 Query 824 EHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 ++ + + L LTY+ +R + L Sbjct 275 IKKVEKGKYYFDFNDWKNISDEAKELIKLMLTYDYNKRCTAEEALNSRW 323 >sp|Q9LY03|IRK_ARATH Probable LRR receptor-like serine/threonine-protein kinase IRK OS=Arabidopsis thaliana OX=3702 GN=IRK PE=1 SV=1 Length=964 Score = 231 bits (589), Expect = 2e-61, Method: Composition-based stats. Identities = 69/282 (24%), Positives = 118/282 (42%), Gaps = 14/282 (5%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 K +LG G FG V T G VA+K L + + +++E+ L L H Sbjct 679 NKDCELGRGGFGAVYR-----TVIRDGYPVAIKKLTVSSLVKSQDEFEREVKKLGKLRHS 733 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMA 1012 +++K +G + L+ E++ GSL L S+ + +A Sbjct 734 NLVKLEGYYWTTSLQ--LLIYEFLSGGSLYKQLHEAPGGNSSLSWNDRFNIILGTAKCLA 791 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE- 1071 YLH + IH ++ + NVLLD+ K+GD+GLA+ +P + Y + S + + APE Sbjct 792 YLHQSNIIHYNIKSSNVLLDSSGEPKVGDYGLARLLPM-LDRYVLSSKIQSALGYMAPEF 850 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + K DV+ FGV + E++T + + L + + + R E ++ Sbjct 851 ACRTVKITEKCDVYGFGVLVLEVVTGKKPVEYMEDDVVVLCDMVREALEDGRADECIDPR 910 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + P + V L C S RP + IL+ + Sbjct 911 LQGKFPVEEAVAVIKLGLICTSQVPSSRPHMGEAVNILRMIR 952 Score = 173 bits (438), Expect = 1e-42, Method: Composition-based stats. Identities = 55/311 (18%), Positives = 100/311 (32%), Gaps = 61/311 (20%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 + + LG+G VY +R V +K L S Sbjct 678 LNKDCELGRGGFGAVYRTVIRDGYP-------------------------VAIKKLTVSS 712 Query 649 H-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG--- 704 F + ++ H++L + G +++ E++ G L L G Sbjct 713 LVKSQDEFEREVKKLGKLRHSNLVKLEGYYWTTSLQLLIYEFLSGGSLYKQLHEAPGGNS 772 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + + A L+YL N++H N+ N+LL G K+ D G+ Sbjct 773 SLSWNDRFNIILGTAKCLAYLHQSNIIHYNIKSSNVLLDSSGEP-------KVGDYGLAR 825 Query 765 GALSREERV------ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + ++APE ++ D +GFG +LE+ G+ P++ Sbjct 826 LLPMLDRYVLSSKIQSALGYMAPE-FACRTVKITEKCDVYGFGVLVLEVV-TGKKPVEYM 883 Query 819 SPSEKEHFYQRQ-----HRLPEPSCPQL------------ATLTSQCLTYEPTQRPSFRT 861 + R E P+L L C + P+ RP Sbjct 884 EDDVVVLCDMVREALEDGRADECIDPRLQGKFPVEEAVAVIKLGLICTSQVPSSRPHMGE 943 Query 862 ILRDLTRLQPH 872 + L ++ Sbjct 944 AVNILRMIRCP 954 >sp|O81291|LRK44_ARATH L-type lectin-domain containing receptor kinase IV.4 OS=Arabidopsis thaliana OX=3702 GN=LECRK44 PE=3 SV=1 Length=669 Score = 226 bits (576), Expect = 2e-61, Method: Composition-based stats. Identities = 81/385 (21%), Positives = 140/385 (36%), Gaps = 32/385 (8%) Query 798 WGFGA----TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEP 853 W FG L + P+ P+ +R + P ++ L Sbjct 258 WSFGVNGEAQPLALSKLPRLPVWDLKPTRV-------YRFYKNWVPLISLLLI----PFL 306 Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 R I++ + + + + K LG G FG V Sbjct 307 LIIFLVRFIMKRRRKFAEEVEDWETEFGKNRLRFKDLYYATKGFKDKNILGSGGFGSV-- 364 Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 Y T + +AVK + + Q + EI + + H +++ G C + E Sbjct 365 --YKGIMPKTKKEIAVKRVSNE-SRQGLKEFVAEIVSIGQMSHRNLVPLVGYCRRRDE-- 419 Query 974 LQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAAR 1027 L LV +Y+P GSL YL P ++ Q + + YLH + IHRD+ A Sbjct 420 LLLVYDYMPNGSLDKYLYNSPEVTLDWKQRFKVINGVASALFYLHEEWEQVVIHRDVKAS 479 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 NVLLD + ++GDFGLA+ G + R + AP+ ++ + +DV++F Sbjct 480 NVLLDAELNGRLGDFGLAQLCDHGSDPQTTR--VVGTWGYLAPDHIRTGRATTTTDVFAF 537 Query 1088 GVTLYELLTHCDSSQ--SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 GV L E+ + + + + L+ + + + K V Sbjct 538 GVLLLEVACGRRPIEINNQSGERVVLVDWVFRFWMEANILDAKDPNLGSEYDQKEVEMVL 597 Query 1146 HLMKNCWETEASFRPTFENLIPILK 1170 L C ++ RPT ++ L+ Sbjct 598 KLGLLCSHSDPLARPTMRQVLQYLR 622 Score = 199 bits (507), Expect = 2e-52, Method: Composition-based stats. Identities = 61/304 (20%), Positives = 103/304 (34%), Gaps = 52/304 (17%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 K + LG G +VY+G + + + +K + Sbjct 346 ATKGFKDKNILGSGGFGSVYKGIM------------------------PKTKKEIAVKRV 381 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ER 703 F + Q+SH +L + G C R E ++V +Y+ +G LD +L Sbjct 382 SNESRQGLKEFVAEIVSIGQMSHRNLVPLVGYCRRRDELLLVYDYMPNGSLDKYLYNSPE 441 Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLA-RLGLAEGTSPFIKLSD 759 + + V +ASAL YL + ++H +V N+LL L G +L D Sbjct 442 VTLDWKQRFKVINGVASALFYLHEEWEQVVIHRDVKASNVLLDAELNGRLGDFGLAQLCD 501 Query 760 PGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 G V +LAP+ + G + +T D + FG LLE+ + Sbjct 502 HG---SDPQTTRVVGTWGYLAPDHIRTGRATTTT--DVFAFGVLLLEVACGRRPIEINNQ 556 Query 820 PSEKEHFYQRQHRLP------------------EPSCPQLATLTSQCLTYEPTQRPSFRT 861 E+ R + + L C +P RP+ R Sbjct 557 SGERVVLVDWVFRFWMEANILDAKDPNLGSEYDQKEVEMVLKLGLLCSHSDPLARPTMRQ 616 Query 862 ILRD 865 +L+ Sbjct 617 VLQY 620 >sp|C0LGV1|RGI2_ARATH LRR receptor-like serine/threonine-protein kinase RGI2 OS=Arabidopsis thaliana OX=3702 GN=RGI2 PE=1 SV=1 Length=1135 Score = 233 bits (593), Expect = 3e-61, Method: Composition-based stats. Identities = 74/322 (23%), Positives = 132/322 (41%), Gaps = 32/322 (10%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL----- 932 P + + L + +G+G G V E++AVK L Sbjct 766 WQFTPFQKLNFTVEHVLKCLVEGNVIGKGCSGIVYKAEMPNR-----EVIAVKKLWPVTV 820 Query 933 ----KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 + R + E+ L ++ H++I+++ GCC ++ + L +Y+ GSL Sbjct 821 PNLNEKTKSSGVRDSFSAEVKTLGSIRHKNIVRFLGCCWNKNTRLLM--YDYMSNGSLGS 878 Query 989 YLPRHS----IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGD 1041 L S +G +G+AYLH +HRD+ A N+L+ D IGD Sbjct 879 LLHERSGVCSLGWEVRYKIILGAAQGLAYLHHDCVPPIVHRDIKANNILIGPDFEPYIGD 938 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FGLAK V +G ++ R + APE K SDV+S+GV + E+LT Sbjct 939 FGLAKLVDDG-DFARSSNTIAGSYGYIAPEYGYSMKITEKSDVYSYGVVVLEVLTGKQPI 997 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH---LMKNCWETEASF 1158 L ++ + +R +++++G + RP+ E+ + C Sbjct 998 DPTIPDGLHIVDWVK----KIRDIQVIDQGLQ-ARPESEVEEMMQTLGVALLCINPIPED 1052 Query 1159 RPTFENLIPILKTVHEKYQGQA 1180 RPT +++ +L + ++ + Sbjct 1053 RPTMKDVAAMLSEICQEREESM 1074 Score = 184 bits (468), Expect = 4e-46, Method: Composition-based stats. Identities = 48/346 (14%), Positives = 106/346 (31%), Gaps = 46/346 (13%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 + + + +G+G VY+ + ++ L Sbjct 785 LVEGNVIGKGCSGIVYKAEMPNREVIAVKKLWPVTVPNLNE---------------KTKS 829 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 + +F + + H ++ G C +++ +Y+ +G L L G + Sbjct 830 SGVRDSFSAEVKTLGSIRHKNIVRFLGCCWNKNTRLLMYDYMSNGSLGSLLHERSGVCSL 889 Query 709 AW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 W + + A L+YL + +VH ++ NIL+ + D G+ Sbjct 890 GWEVRYKIILGAAQGLAYLHHDCVPPIVHRDIKANNILIGPDFEPY-------IGDFGLA 942 Query 764 L------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 A S ++APE G + ++ D + +G +LE+ G+ P+ Sbjct 943 KLVDDGDFARSSNTIAGSYGYIAPEY--GYSMKITEKSDVYSYGVVVLEVL-TGKQPIDP 999 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 P + H ++ + + Q L P +++ L Sbjct 1000 TIP-DGLHIVDWVKKIRDI------QVIDQGLQARPESE--VEEMMQTLGVALLCINPIP 1050 Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923 + + ++ + G G + +D T Sbjct 1051 EDRPTMKDVAAMLSEICQEREESMKVD-GCSGSCNNGRERGKDDST 1095 >sp|Q28GW8|MELK_XENTR Maternal embryonic leucine zipper kinase OS=Xenopus tropicalis OX=8364 GN=melk PE=2 SV=1 Length=652 Score = 226 bits (575), Expect = 3e-61, Method: Composition-based stats. Identities = 70/274 (26%), Positives = 122/274 (45%), Gaps = 26/274 (9%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 Y + +G G F KV L ++ TGE VA+K + + K EID ++ L Sbjct 12 YYELHETIGTGGFAKVKL----ASHLTTGEKVAIKIMDKESLGDDLPRVKTEIDAMKNLS 67 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYL 1014 H+H+ + E + + +V+EY P G L DY+ + + + +F +QI +AY+ Sbjct 68 HQHVCRLYHVIETPNK--IFMVLEYCPGGELFDYIIAKDRLTEDEARVFFRQIVSAVAYI 125 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H+Q Y HRDL N+L+D D+ +K+ DFGL G +Y+ + + APE ++ Sbjct 126 HSQGYAHRDLKPENLLIDEDQNLKLIDFGLCAKPKGGLDYHLM--TCCGSPAYAAPELIQ 183 Query 1075 EYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + +D+WS GV +Y L+ V+ L + + RG + Sbjct 184 GKAYIGSEADIWSMGVLMYALMCGYLPFDDD---------------NVMVLYKKIMRG-K 227 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P L+ + + R + ++L+ Sbjct 228 YEIPKWLSPGSVLLLSQMLQVDPKKRISVKHLLS 261 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 51/319 (16%), Positives = 99/319 (31%), Gaps = 39/319 (12%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH- 648 +G G V G +V +K++D Sbjct 14 ELHETIGTGGFAKVKLASHLTTGE------------------------KVAIKIMDKESL 49 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 D M +SH H+ ++ V + MV EY G L ++ + + Sbjct 50 GDDLPRVKTEIDAMKNLSHQHVCRLYHVIETPNKIFMVLEYCPGGELFDYIIA-KDRLTE 108 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA-- 766 V +Q+ SA++Y+ ++ H ++ N+L+ +KL D G+ Sbjct 109 DEARVFFRQIVSAVAYIHSQGYAHRDLKPENLLIDE-------DQNLKLIDFGLCAKPKG 161 Query 767 ---LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + APE + G A + + D W G + + Sbjct 162 GLDYHLMTCCGSPAYAAPELIQGKAY-IGSEADIWSMGVLMYALMCGYLPFDDDNVMVLY 220 Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 + + ++ +P+ P L SQ L +P +R S + +L +Q ++ Sbjct 221 KKIMRGKYEIPKWLSPGSVLLLSQMLQVDPKKRISVKHLLSHPWLMQGYSCPVEWQSKYP 280 Query 884 SPASDPTVFHKRYLKKIRD 902 D + + Sbjct 281 LGYVDEDCVTELSVFYKCS 299 >sp|Q6AXJ9|CDKL1_DANRE Cyclin-dependent kinase-like 1 OS=Danio rerio OX=7955 GN=cdkl1 PE=2 SV=1 Length=350 Score = 216 bits (551), Expect = 3e-61, Method: Composition-based stats. Identities = 72/306 (24%), Positives = 133/306 (43%), Gaps = 31/306 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILR 952 +KI +GEG +G V + N TG++VA+K ++++ P + +EI +L+ Sbjct 1 MEKYEKISKIGEGSYGVV----FKCRNKDTGQIVAIKKFVESEDDPIIKKIALREIRMLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEG 1010 L H +++ + + L LV EY L + L R+ + + Q + Sbjct 57 QLKHPNLVNLMEVFRRK--RKLHLVFEYCDHTVLNE-LDRYPRGVPEHMVKSIIWQTLQA 113 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 + + H Q+ IHRD+ N+L+ +++K+ DFG A+ + +YY D + ++ AP Sbjct 114 VNFCHKQNCIHRDVKPENILITKHQVIKLCDFGFARILTGPCDYY---TDCVATRWYRAP 170 Query 1071 ECL-KEYKFYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRL 1124 E L + ++ DVW+ G ELL+ S + +G + + Sbjct 171 ELLVGDTQYGPPVDVWAVGCVFAELLSGAPLWPGKSDVDQLYLIRKTLGELIPRHQQVFS 230 Query 1125 TELLERGERLPRPDKC-PCEVY---------HLMKNCWETEASFRPTFENLI--PILKTV 1172 T G +P P + P E+ LMK C + + R + E L+ P ++ Sbjct 231 TNQFFSGVCVPEPQEMEPLELKYPNLSYQALSLMKGCLRMDPAERLSCEQLLEQPYFDSL 290 Query 1173 HEKYQG 1178 E+ + Sbjct 291 REESES 296 Score = 156 bits (394), Expect = 3e-40, Method: Composition-based stats. Identities = 51/250 (20%), Positives = 91/250 (36%), Gaps = 40/250 (16%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ ++S +G+G+ V++ R + G V +K Sbjct 1 MEKYEKISKIGEGSYGVVFKCRNKDTGQ------------------------IVAIKKFV 36 Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 S D I ++ Q+ H +L + V R + +V EY +H L+ R R Sbjct 37 ESEDDPIIKKIALREIRMLKQLKHPNLVNLMEVFRRKRKLHLVFEYCDHTVLNELDRYPR 96 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 G VP + Q A+++ +N +H +V NIL+ + + IKL D G Sbjct 97 G-VPEHMVKSIIWQTLQAVNFCHKQNCIHRDVKPENILITKHQV-------IKLCDFGFA 148 Query 764 LGAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + V + APE L G +D W G E+ G +S Sbjct 149 RILTGPCDYYTDCVATRWYRAPELLV-GDTQYGPPVDVWAVGCVFAELLS-GAPLWPGKS 206 Query 820 PSEKEHFYQR 829 ++ + ++ Sbjct 207 DVDQLYLIRK 216 >sp|Q69Q47|CIPKO_ORYSJ CBL-interacting protein kinase 24 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK24 PE=1 SV=1 Length=453 Score = 220 bits (560), Expect = 3e-61, Method: Composition-based stats. Identities = 65/268 (24%), Positives = 110/268 (41%), Gaps = 29/268 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTLYHEHI 959 +G+G F KV + TG VA+K L D HR K+EI I++ + H +I Sbjct 23 TIGQGTFAKVKF----AVDADTGAAVAMKVLDKDTILNHRMLHQIKREISIMKIVRHPNI 78 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ G+ + +++E + G L D + R + + + QQ+ + + Y H++ Sbjct 79 VRLNEVLA--GKTKIYIILELITGGELFDKIARQGKLRENEARKYFQQLIDAINYCHSKG 136 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N+LLD+ +K+ DFGL+ +G + APE L + Sbjct 137 VYHRDLKPENLLLDSRGNLKVSDFGLSTLAQKGVGLLHTT---CGTPNYVAPEVLSNNGY 193 Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 A+DVWS GV LY L+ + + + L + + G + P Sbjct 194 DGSAADVWSCGVILYVLMAGYLPFE---------------EDDLPTLYDKITAG-QFSCP 237 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165 L+ + R T E + Sbjct 238 YWFSPGATSLIHRILDPNPKTRITIEQI 265 Score = 182 bits (463), Expect = 2e-48, Method: Composition-based stats. Identities = 60/294 (20%), Positives = 98/294 (33%), Gaps = 42/294 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 RV + E+ +GQGT V D V + Sbjct 13 KRVGRYEV--GRTIGQGTFAKV------------------------KFAVDADTGAAVAM 46 Query 642 KVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 KVLD +H + S+M V H ++ ++ V + ++ E + G L Sbjct 47 KVLDKDTILNHRMLHQIKREISIMKIVRHPNIVRLNEVLAGKTKIYIILELITGGELFDK 106 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + R+ G + QQL A++Y +K + H ++ N+LL G +K+S Sbjct 107 IARQ-GKLRENEARKYFQQLIDAINYCHSKGVYHRDLKPENLLLDSRG-------NLKVS 158 Query 759 DPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 D G+ A ++APE L +A D W G L + Sbjct 159 DFGLSTLAQKGVGLLHTTCGTPNYVAPEVLSNNGYD-GSAADVWSCGVILYVLMAGYLPF 217 Query 815 LQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + P+ + Q P P +L + L P R + I D Sbjct 218 EEDDLPTLYDKITAGQFSCPYWFSPGATSLIHRILDPNPKTRITIEQIREDTWF 271 >sp|Q8LIG4|CIPK3_ORYSJ CBL-interacting protein kinase 3 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK3 PE=2 SV=1 Length=445 Score = 219 bits (559), Expect = 3e-61, Method: Composition-based stats. Identities = 62/269 (23%), Positives = 112/269 (42%), Gaps = 27/269 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHII 960 +G+G F KV N TG+ VA+K L +HR ++EI ++ + H +++ Sbjct 25 IGQGTFAKVRF----AKNMETGDHVAIKILDKAKVQKHRLVEQIRREICTMKLIQHPNVV 80 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + + +V+EYV G L D + + + + QQ+ + Y H++ Sbjct 81 HLHEVM--GSKTRIFIVLEYVMGGELHDIIATSGRLKEDEARKYFQQLINAVDYCHSRGV 138 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 HRDL N+LLD +K+ DFGL+ + + +P + APE +++ + Sbjct 139 YHRDLKLENLLLDTAGNIKVSDFGLSAISEQVKADGLLHTTCGTPN-YVAPEVIEDKGYD 197 Query 1080 YA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 A +D+WS GV L+ LL + E I +++ G + P Sbjct 198 GALADLWSCGVILFVLLAGYLPFED------ENIVSLYNKIS----------GAQFTCPS 241 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIP 1167 E L+ + + R T ++ Sbjct 242 WFSAEAKRLIARILDPNPATRITTSQVLQ 270 Score = 169 bits (428), Expect = 8e-44, Method: Composition-based stats. Identities = 52/312 (17%), Positives = 94/312 (30%), Gaps = 44/312 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + +GQGT V ++ V +K+LD + Sbjct 18 KYELGRAIGQGTFAKV------------------------RFAKNMETGDHVAIKILDKA 53 Query 648 HHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + M + H ++ +H V +V EYV G L + G Sbjct 54 KVQKHRLVEQIRREICTMKLIQHPNVVHLHEVMGSKTRIFIVLEYVMGGELHDII-ATSG 112 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + QQL +A+ Y ++ + H ++ N+LL G IK+SD G+ Sbjct 113 RLKEDEARKYFQQLINAVDYCHSRGVYHRDLKLENLLLDTAG-------NIKVSDFGLSA 165 Query 765 GALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + + ++APE + D W G L + G P + Sbjct 166 ISEQVKADGLLHTTCGTPNYVAPEVIEDKGYD-GALADLWSCGVIL-FVLLAGYLPFEDE 223 Query 819 SPSEKEH-FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 + + Q P + L ++ L P R + +L+D + + Sbjct 224 NIVSLYNKISGAQFTCPSWFSAEAKRLIARILDPNPATRITTSQVLQDQWFKKGYESPVF 283 Query 878 LTVNPDSPASDP 889 Sbjct 284 DDKYYPYFHDVY 295 >sp|Q9LZV7|PXC2_ARATH Leucine-rich repeat receptor-like protein kinase PXC2 OS=Arabidopsis thaliana OX=3702 GN=PXC2 PE=1 SV=1 Length=967 Score = 231 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 70/276 (25%), Positives = 120/276 (43%), Gaps = 11/276 (4%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +LG G FG V T+ G VAVK L + + +++E+ L L H+++++ Sbjct 692 ELGRGGFGVVYK-----TSLQDGRPVAVKKLTVSGLIKSQEEFEREMRKLGKLRHKNVVE 746 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018 KG Q + L+ E+V GSL +L + Q I G+A+LH+ + Sbjct 747 IKGYYWTQSLQ--LLIHEFVSGGSLYRHLHGDESVCLTWRQRFSIILGIARGLAFLHSSN 804 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE-CLKEYK 1077 H ++ A NVL+D K+ DFGLA+ + + + S + + APE + K Sbjct 805 ITHYNMKATNVLIDAAGEAKVSDFGLARLLASALDRCVLSGKVQSALGYTAPEFACRTVK 864 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 DV+ FG+ + E++T + + L + + R+ E ++ R P Sbjct 865 ITDRCDVYGFGILVLEVVTGKRPVEYAEDDVVVLCETVREGLEEGRVEECVDPRLRGNFP 924 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + V L C S RP E ++ IL+ + Sbjct 925 AEEAIPVIKLGLVCGSQVPSNRPEMEEVVKILELIQ 960 Score = 167 bits (423), Expect = 7e-41, Method: Composition-based stats. Identities = 58/313 (19%), Positives = 109/313 (35%), Gaps = 60/313 (19%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 + + S LG+G VY+ L+ V +K L S Sbjct 687 LNKDSELGRGGFGVVYKTSLQDGRP-------------------------VAVKKLTVSG 721 Query 649 H-DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-V 706 F + ++ H ++ + G +++ E+V G L L + + Sbjct 722 LIKSQEEFEREMRKLGKLRHKNVVEIKGYYWTQSLQLLIHEFVSGGSLYRHLHGDESVCL 781 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + + +A L++L + N+ H N+ N+L+ G A K+SD G+ Sbjct 782 TWRQRFSIILGIARGLAFLHSSNITHYNMKATNVLIDAAGEA-------KVSDFGLARLL 834 Query 767 LSREERV-------ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 S +R + + APE ++ D +GFG +LE+ G+ P++ Sbjct 835 ASALDRCVLSGKVQSALGYTAPE-FACRTVKITDRCDVYGFGILVLEVV-TGKRPVEYAE 892 Query 820 PS-----EKEHFYQRQHRLPEPSCPQLA------------TLTSQCLTYEPTQRPSFRTI 862 E + R+ E P+L L C + P+ RP + Sbjct 893 DDVVVLCETVREGLEEGRVEECVDPRLRGNFPAEEAIPVIKLGLVCGSQVPSNRPEMEEV 952 Query 863 LRDLTRLQPHNLA 875 ++ L +Q + Sbjct 953 VKILELIQCPSHD 965 >sp|Q9M3D7|LRK14_ARATH Putative L-type lectin-domain containing receptor kinase I.4 OS=Arabidopsis thaliana OX=3702 GN=LECRK14 PE=3 SV=1 Length=667 Score = 226 bits (575), Expect = 3e-61, Method: Composition-based stats. Identities = 68/276 (25%), Positives = 110/276 (40%), Gaps = 18/276 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FGKV G +AVK L D Q + E+ + + H +++ Sbjct 356 VGKGGFGKVYKGTLPG-----GRHIAVKRLSHDA-EQGMKQFVAEVVTMGNIQHRNLVPL 409 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA--- 1016 G C +GE L LV EY+ GSL YL S Q + + I + YLH+ Sbjct 410 LGYCRRKGE--LLLVSEYMSNGSLDQYLFYNQNPSPSWLQRISILKDIASALNYLHSGAN 467 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRD+ A NV+LD++ ++GDFG+AK + + + + APE ++ Sbjct 468 PAVLHRDIKASNVMLDSEYNGRLGDFGMAKF--QDPQGNLSATAAVGTIGYMAPELIRTG 525 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 +DV++FG+ L E+ + P + L+ L E + Sbjct 526 T-SKETDVYAFGIFLLEVTCGRRPFEPELPVQKKYLVKWVCECWKQASLLETRDPKLGRE 584 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + V L C RP ++ L Sbjct 585 FLSEEVEMVLKLGLLCTNDVPESRPDMGQVMQYLSQ 620 Score = 218 bits (555), Expect = 1e-58, Method: Composition-based stats. Identities = 81/422 (19%), Positives = 145/422 (34%), Gaps = 81/422 (19%) Query 471 YLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELG 530 Y++ WS S + ++ R + P+ +++ + P + L Sbjct 250 YILGWSFSKSKEFMQSL--DLSKLPQAPIPRNEQAPVPREE-------KKKLHPLLIGLV 300 Query 531 AALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEIT 590 L +L + RR + E+ S S ++ Sbjct 301 ILLVIPVLMVLGGVYWYRRKKYAEVKESWEKEYG--------PHRYSYKSLYK-ATNGFV 351 Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + + +G+G VY+G L + +K L Sbjct 352 KDALVGKGGFGKVYKGTLPGGRH-------------------------IAVKRLSHDAEQ 386 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP-MA 709 F M + H +L + G C R E ++V+EY+ +G LD +L + P Sbjct 387 GMKQFVAEVVTMGNIQHRNLVPLLGYCRRKGELLLVSEYMSNGSLDQYLFYNQNPSPSWL 446 Query 710 WKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-- 764 ++ + + +ASAL+YL + ++H ++ N++L +L D G+ Sbjct 447 QRISILKDIASALNYLHSGANPAVLHRDIKASNVMLDSEYNG-------RLGDFGMAKFQ 499 Query 765 ---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 G LS V I ++APE + G S D + FG LLE+ G P + P Sbjct 500 DPQGNLSATAAVGTIGYMAPELIRTGT---SKETDVYAFGIFLLEV-TCGRRPFEPELPV 555 Query 822 EKEHF------YQRQHRLPEPSCPQL------------ATLTSQCLTYEPTQRPSFRTIL 863 +K++ +Q L E P+L L C P RP ++ Sbjct 556 QKKYLVKWVCECWKQASLLETRDPKLGREFLSEEVEMVLKLGLLCTNDVPESRPDMGQVM 615 Query 864 RD 865 + Sbjct 616 QY 617 >sp|Q54MV2|MRKB_DICDI Probable serine/threonine-protein kinase MARK-B OS=Dictyostelium discoideum OX=44689 GN=mrkB PE=3 SV=1 Length=715 Score = 227 bits (578), Expect = 3e-61, Method: Composition-based stats. Identities = 70/289 (24%), Positives = 114/289 (39%), Gaps = 23/289 (8%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 N + +G G KV + TN TG+ A+K K Sbjct 47 YRNKPQQQQHKKGHKMGNYLLGKTIGSGTSSKVKIG----TNILTGKQYAIKITKPK-RI 101 Query 939 QHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGL 997 + R ++EI IL+ L H++II+ + + L++E V G L DY+ R + Sbjct 102 KERKEIEREISILKRLKHDNIIQLHDAIYEDDVGRICLILELVSGGELFDYIVARGRLSE 161 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + F +Q+ G+ Y H+ HRDL N+L+D D +KI DFG + + G+ + Sbjct 162 KEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDGNLKISDFGYSNIIKPGN----L 217 Query 1058 REDGDSPVFWYAPECLKEYKFYY-ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 + PE L E ++ D+WS GV LY ++T +L Sbjct 218 LSTFCGSPVYAPPEILLEKRYNGNEVDIWSMGVILYAMVTG------------QLPWTLT 265 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + V + LL + P +V L+ E R T + + Sbjct 266 DGVQVEGMDRLLRGEFKYPSHVILSDDVKDLINRMIVAEPVERATLDEI 314 Score = 155 bits (391), Expect = 2e-37, Method: Composition-based stats. Identities = 39/288 (14%), Positives = 91/288 (32%), Gaps = 20/288 (7%) Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663 ++ ++ + + G + + +K+ P S++ Sbjct 56 HKKGHKMGNYLLGKTIGSGTSSKVKIGTNILTGKQYAIKITKPKRIKERKEIEREISILK 115 Query 664 QVSHTHLAFVHGVCVRGP--ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASA 721 ++ H ++ +H ++ E V G L ++ RG + +Q+ Sbjct 116 RLKHDNIIQLHDAIYEDDVGRICLILELVSGGELFDYI-VARGRLSEKEGRKFFRQMLCG 174 Query 722 LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPW 778 L Y + + H ++ N+L+ G +K+SD G + Sbjct 175 LIYCHSNMVCHRDLKLENLLVDEDG-------NLKISDFGYSNIIKPGNLLSTFCGSPVY 227 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-----RQHRL 833 PE L + +D W G L + G+ P + E + ++ Sbjct 228 APPEILLEKRYN-GNEVDIWSMGVILYAMV-TGQLPWTLTDGVQVEGMDRLLRGEFKYPS 285 Query 834 PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 + L ++ + EP +R + I + + +++ N Sbjct 286 HVILSDDVKDLINRMIVAEPVERATLDEIKTHVWVNKGYDMEPDQEYN 333 >sp|A8WYE4|PAR1_CAEBR Serine/threonine-protein kinase par-1 OS=Caenorhabditis briggsae OX=6238 GN=par-1 PE=3 SV=1 Length=1088 Score = 232 bits (591), Expect = 3e-61, Method: Composition-based stats. Identities = 74/269 (28%), Positives = 117/269 (43%), Gaps = 29/269 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHII 960 +G+G+F KV L + TG VA+K + P +E+ I++ L H +I+ Sbjct 133 TIGKGNFAKVKL----AKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIV 188 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHY 1019 K E E++L LV+EY G + DYL H + + +QI + YLH+++ Sbjct 189 KLYQVME--TEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNI 246 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRDL A N+LLD D +KI DFG + G++ + + APE K+ Sbjct 247 IHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKL----DTFCGSPPYAAPELFSGKKYD 302 Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 DVWS GV LY L++ + L E + RG + P Sbjct 303 GPEVDVWSLGVILYTLVSGSLPFD---------------GQNLKELRERVLRG-KYRIPF 346 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + +L+K R + +N++ Sbjct 347 YMSTDCENLLKKFLVINPQRRSSLDNIMK 375 Score = 197 bits (502), Expect = 3e-50, Method: Composition-based stats. Identities = 58/322 (18%), Positives = 111/322 (34%), Gaps = 50/322 (16%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 + S + AR + + +++ + L +G+G V + + G Sbjct 102 ARSSGQSGMSSRSAARRNDQDVHVGKYK----------LLKTIGKGNFAKVKLAKHVITG 151 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHL 670 V +K++D + + + + +M Q+ H ++ Sbjct 152 H------------------------EVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNI 187 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730 ++ V +V EY G + +L G + +Q+ SA+ YL +KN+ Sbjct 188 VKLYQVMETEQTLYLVLEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYLHSKNI 246 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG---ALSREERVERIPWLAPECLPGG 787 +H ++ N+LL + IK++D G + P+ APE G Sbjct 247 IHRDLKAENLLLDQ-------DMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGK 299 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTS 846 +D W G L + G P ++ E R +R+P L Sbjct 300 KYD-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLK 357 Query 847 QCLTYEPTQRPSFRTILRDLTR 868 + L P +R S I++D Sbjct 358 KFLVINPQRRSSLDNIMKDRWM 379 >sp|O01700|DLK1_CAEEL Mitogen-activated protein kinase kinase kinase dlk-1 OS=Caenorhabditis elegans OX=6239 GN=dlk-1 PE=1 SV=4 Length=928 Score = 230 bits (587), Expect = 4e-61, Method: Composition-based stats. Identities = 75/277 (27%), Positives = 117/277 (42%), Gaps = 34/277 (12%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + ++ LG G G V + VAVK + + EI Sbjct 128 WEIPFDAISELEWLGSGSQGAVFRGQLE------NRTVAVKKVNQLK--------ETEIK 173 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQIC 1008 LR L H++II++ G C +VMEY G L L R++I + ++I Sbjct 174 HLRHLRHQNIIEFLGVCSKS--PCYCIVMEYCSKGQLCTVLKSRNTITRELFAQWVKEIA 231 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +GM YLH IHRDL + N+L+ + +KI DFG + + V W Sbjct 232 DGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTSHM---QKKMDSTMMSFCGTVSWM 288 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 APE +K+ DV+SFGV L+E+LT ++P ++ I +L Sbjct 289 APEMIKKQPCNEKVDVYSFGVVLWEMLTR----ETPYANIAQMAIIFGVGTNILS----- 339 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 LP P++ P + L+K C + RP+F ++ Sbjct 340 -----LPMPEEAPKGLVLLIKQCLSQKGRNRPSFSHI 371 Score = 202 bits (515), Expect = 3e-52, Method: Composition-based stats. Identities = 60/338 (18%), Positives = 109/338 (32%), Gaps = 51/338 (15%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S+ + I++L LG G++ V+ G+L + Sbjct 123 SEDELWEIPFDAISELEWLGSGSQGAVFRGQL--------------------------EN 156 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K ++ + + H ++ GVC + P +V EY G L Sbjct 157 RTVAVKKVNQLKE-------TEIKHLRHLRHQNIIEFLGVCSKSPCYCIVMEYCSKGQLC 209 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 L + R + +++A + YL ++H ++ NIL++ IK Sbjct 210 TVL-KSRNTITRELFAQWVKEIADGMHYLHQNKVIHRDLKSPNILIS-------AEDSIK 261 Query 757 LSDPGVGLGALSREERV----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 + D G + + + W+APE + + +D + FG L E+ E Sbjct 262 ICDFGTSHMQKKMDSTMMSFCGTVSWMAPEMIK--KQPCNEKVDVYSFGVVLWEMLTR-E 318 Query 813 APLQSRSPSEKEH---FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 P + + +PE + L L QCL+ + RPSF I + Sbjct 319 TPYANIAQMAIIFGVGTNILSLPMPEEAPKGLVLLIKQCLSQKGRNRPSFSHIRQHWEIF 378 Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 +P + S G Sbjct 379 KPELFEMTEEEWQLAWDSYREFAKCIQYPSTVTRDHGG 416 >sp|Q39203|SD22_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase SD2-2 OS=Arabidopsis thaliana OX=3702 GN=SD22 PE=1 SV=1 Length=797 Score = 228 bits (582), Expect = 4e-61, Method: Composition-based stats. Identities = 72/286 (25%), Positives = 121/286 (42%), Gaps = 29/286 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V + T G+ VAVK L+ S ++ E+ + + H ++++ Sbjct 466 KVGHGGFGAV----FKGTLPGSSTFVAVKRLERPGS--GESEFRAEVCTIGNIQHVNLVR 519 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHA-- 1016 +G C + + LV +Y+P GSL YL R S + A +G+AYLH Sbjct 520 LRGFCSENLHR--LLVYDYMPQGSLSSYLSRTSPKLLSWETRFRIALGTAKGIAYLHEGC 577 Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 IH D+ N+LLD+D K+ DFGLAK + G ++ RV + APE + Sbjct 578 RDCIIHCDIKPENILLDSDYNAKVSDFGLAKLL--GRDFSRVLATMRGTWGYVAPEWISG 635 Query 1076 YKFYYASDVWSFGVTLYELL-----------THCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 +DV+SFG+TL EL+ T + P F A ++ + Sbjct 636 LPITTKADVYSFGMTLLELIGGRRNVIVNSDTLGEKETEPEKWFFPP--WAAREIIQGNV 693 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +++ + + + C + RP ++ +L+ Sbjct 694 DSVVDSRLNGEYNTEEVTRMATVAIWCIQDNEEIRPAMGTVVKMLE 739 Score = 197 bits (502), Expect = 5e-51, Method: Composition-based stats. Identities = 53/272 (19%), Positives = 91/272 (33%), Gaps = 43/272 (16%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 LNL SF + +G G V++G L Sbjct 446 LNLKVFSFKELQSATNGFSDKVGHGGFGAVFKGTL------------------------P 481 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 G V +K L F + + H +L + G C ++V +Y+ G Sbjct 482 GSSTFVAVKRL-ERPGSGESEFRAEVCTIGNIQHVNLVRLRGFCSENLHRLLVYDYMPQG 540 Query 694 PLDVWLRRERGH-VPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAE 749 L +L R + + +A A ++YL ++H ++ NILL Sbjct 541 SLSSYLSRTSPKLLSWETRFRIALGTAKGIAYLHEGCRDCIIHCDIKPENILLD------ 594 Query 750 GTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 + K+SD G+ RV ++APE + G ++T D + FG TL Sbjct 595 -SDYNAKVSDFGLAKLLGRDFSRVLATMRGTWGYVAPEWISG--LPITTKADVYSFGMTL 651 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP 836 LE+ + + ++ + P Sbjct 652 LELIGGRRNVIVNSDTLGEKETEPEKWFFPPW 683 >sp|A2QRF6|HOG1_ASPNC Mitogen-activated protein kinase hog1 OS=Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) OX=425011 GN=hog1 PE=3 SV=2 Length=365 Score = 217 bits (552), Expect = 4e-61, Method: Composition-based stats. Identities = 66/283 (23%), Positives = 108/283 (38%), Gaps = 29/283 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + TG+ VAVK + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SARDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 D+WS E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAACIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L + ER P + + L++ + R + Sbjct 252 SLPKRERQPLASKFKNADPDAVDLLERMLVFDPKKRIRAGEAL 294 Score = 132 bits (331), Expect = 6e-32, Method: Composition-based stats. Identities = 35/231 (15%), Positives = 73/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + RD+ V +K ++ P ++ Y Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSARDQLTGQPVAVKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAACIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q75V57|SAPK9_ORYSJ Serine/threonine-protein kinase SAPK9 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK9 PE=1 SV=1 Length=361 Score = 217 bits (552), Expect = 4e-61, Method: Composition-based stats. Identities = 71/284 (25%), Positives = 119/284 (42%), Gaps = 26/284 (9%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 P + + ++++G G+FG L N +G++VAVK + D G + + Sbjct 11 MEMPIMHDGDRYELVKEIGSGNFGVARLM----RNRASGDLVAVKYI--DRGEKIDENVQ 64 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFA 1004 +EI R+L H +II++K L +VMEY G L + + + F Sbjct 65 REIINHRSLRHPNIIRFKEVILTPTH--LAIVMEYASGGELFERICSAGRFSEDEARFFF 122 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGD 1062 QQ+ G++Y H+ HRDL N LLD +KI DFG +K + + + Sbjct 123 QQLISGVSYCHSMQVCHRDLKLENTLLDGSTAPRLKICDFGYSK---SSVLHSQPKSTVG 179 Query 1063 SPVFWYAPECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 +P + APE L + ++ +DVWS GVTLY +L + P + Sbjct 180 TPA-YIAPEVLLKKEYDGKIADVWSCGVTLYVMLVGAYPFEDPED----------PKNFR 228 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + ++L +P E L+ + + R T + Sbjct 229 KTIQKILGVQYSIPDYVHISPECRDLITRIFVGNPASRITMPEI 272 Score = 164 bits (415), Expect = 6e-43, Method: Composition-based stats. Identities = 57/346 (16%), Positives = 102/346 (29%), Gaps = 43/346 (12%) Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 RA+ L + H D+ E+ +G G Sbjct 3 RAAAGPLGMEMPIMHDGDRYELV--KEIGSGNFG------------------------VA 36 Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 R+R V +K +D I + H ++ V + +V Sbjct 37 RLMRNRASGDLVAVKYIDRG-EKIDENVQREIINHRSLRHPNIIRFKEVILTPTHLAIVM 95 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 EY G L + G QQL S +SY + + H ++ N LL Sbjct 96 EYASGGELFERI-CSAGRFSEDEARFFFQQLISGVSYCHSMQVCHRDLKLENTLLD---- 150 Query 748 AEGTSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 T+P +K+ D G ++ + V ++APE L D W G TL Sbjct 151 -GSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYD-GKIADVWSCGVTL 208 Query 805 LEICFDGEAPLQSRSPSE----KEHFYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPS 858 + P + Q+ +P+ P+ L ++ P R + Sbjct 209 YVMLVGAYPFEDPEDPKNFRKTIQKILGVQYSIPDYVHISPECRDLITRIFVGNPASRIT 268 Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 I ++ + + +P + + ++ L Sbjct 269 MPEIKNHPWFMKNIPADLMDDGMVSNQYEEPDQPMQNMNEIMQILA 314 >sp|Q869X3|Y9851_DICDI Probable serine/threonine-protein kinase DDB_G0275165 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0275165 PE=3 SV=1 Length=921 Score = 230 bits (586), Expect = 4e-61, Method: Composition-based stats. Identities = 76/278 (27%), Positives = 127/278 (46%), Gaps = 33/278 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR----SGWKQEIDILRTLYHEH 958 +G G FGKV + G +K + +R ++EI L+ L H + Sbjct 29 IGSGGFGKVYQGVLNGKEIG------IKKITISDNDPNRDILLKFLEREIYTLKMLSHPN 82 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLLFAQQICEGMAYLHA 1016 +IK+ G E E+SL L+ E V G L Y+ SI + A+ I MAYLH Sbjct 83 VIKFYGIAEK--ERSLFLLTELVSGGDLHWYIKNKSIDITWKLKVKIARDIAASMAYLHE 140 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRDL + N+L+ + ++K+ D GLA+ + + + + W APE L Sbjct 141 NGVIHRDLKSTNLLVAENWVIKVCDMGLARKMDKSE---KSKMTICGTDDWMAPEVLIGE 197 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 ++ + DV+SFG+ L EL+T + +P + +L + ++ + Sbjct 198 EYDASCDVFSFGMVLIELITRENL--TPRIRNEDLGVDQKFFLSKV-------------- 241 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 P CP E+ L+ C + S RP+ N++ +L+ + E Sbjct 242 PADCPKELLRLVSECCKVAPSGRPSASNILGLLEYILE 279 Score = 201 bits (511), Expect = 9e-52, Method: Composition-based stats. Identities = 63/283 (22%), Positives = 116/283 (41%), Gaps = 36/283 (13%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 D+ + LS +G G VY+G L + G ++ + D DP Sbjct 19 DEIKFDPLSIIGSGGFGKVYQGVLNGKEIG-IKKITISDNDP------------------ 59 Query 645 DPSHHDIALAFYE-TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + DI L F E + +SH ++ +G+ + ++TE V G L +++ + Sbjct 60 ---NRDILLKFLEREIYTLKMLSHPNVIKFYGIAEKERSLFLLTELVSGGDLHWYIKNKS 116 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + K+ +A+ +A++++YL ++H ++ N+L+A + IK+ D G+ Sbjct 117 IDITWKLKVKIARDIAASMAYLHENGVIHRDLKSTNLLVAE-------NWVIKVCDMGLA 169 Query 764 LGALSREERVERIP----WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 E+ I W+APE L G + D + FG L+E+ + R+ Sbjct 170 RKMDKSEKSKMTICGTDDWMAPEVLIG--EEYDASCDVFSFGMVLIELITRENLTPRIRN 227 Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 ++P +L L S+C P+ RPS I Sbjct 228 EDLGVDQKFFLSKVPADCPKELLRLVSECCKVAPSGRPSASNI 270 >sp|Q54TN4|MKCE_DICDI Probable serine/threonine-protein kinase mkcE OS=Dictyostelium discoideum OX=44689 GN=mkcE PE=3 SV=1 Length=715 Score = 226 bits (577), Expect = 4e-61, Method: Composition-based stats. Identities = 64/321 (20%), Positives = 126/321 (39%), Gaps = 20/321 (6%) Query 849 LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG--EG 906 L+ P +P R+ + + + L +I + +G Sbjct 377 LSQNPPIQPMRRSDYNRIFIEPGKFYIFPESESFALARLVVEEEDPSKLFRIGENAEVKG 436 Query 907 HFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC 966 FG V Y VA+K + + R+ EI ILR L H +I+ Y Sbjct 437 AFGTVYQVFY-VNGQYNNVDVALKKMDHKSEKKRRNN-LNEISILRYLKHPNIVTYINSY 494 Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 E E+ + +VMEY+ G++RD + + + ++I + YL + + HRDL + Sbjct 495 EKNDEE-IWMVMEYMDGGTIRDAISNFTFTEKYVAYITKEILHSLEYLASLNIAHRDLKS 553 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 N+++++ VK+ DFG + + + + + F+ +PE +++ A D+WS Sbjct 554 SNIMINSKAEVKLIDFGFSIDL----THLKQDINMCGSPFYMSPEQIQDKAHGLAVDIWS 609 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 G+ + E++ K + L G + + + E++ Sbjct 610 LGIVVAEMVRGRVPHHKSKIKAMFLAGTVGVKFSKEKKYSC-----------HWSPELFD 658 Query 1147 LMKNCWETEASFRPTFENLIP 1167 + C + + + RPT L+ Sbjct 659 FLNVCLQMDPTKRPTPTQLLQ 679 Score = 171 bits (432), Expect = 1e-42, Method: Composition-based stats. Identities = 49/299 (16%), Positives = 106/299 (35%), Gaps = 48/299 (16%) Query 584 VDQKEITQLSHLGQ-----GTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR 638 V++++ ++L +G+ G VY+ + + + Sbjct 417 VEEEDPSKLFRIGENAEVKGAFGTVYQ---------------------VFYVNGQYNNVD 455 Query 639 VVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDV 697 V LK +D S++ + H ++ + E MV EY++ G + Sbjct 456 VALKKMDHKSEKKRRNNLNEISILRYLKHPNIVTYINSYEKNDEEIWMVMEYMDGGTIRD 515 Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + + + +++ +L YL + N+ H ++ NI++ +KL Sbjct 516 AISN--FTFTEKYVAYITKEILHSLEYLASLNIAHRDLKSSNIMINSK-------AEVKL 566 Query 758 SDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 D G + + +++PE + A+ L A+D W G + E+ G P Sbjct 567 IDFGFSIDLTHLKQDINMCGSPFYMSPEQIQDKAHGL--AVDIWSLGIVVAEMV-RGRVP 623 Query 815 LQSRSPSEKEHF------YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + ++ + P+L + CL +PT+RP+ +L+ Sbjct 624 HHKSKIKAMFLAGTVGVKFSKEKKYSCHWSPELFDFLNVCLQMDPTKRPTPTQLLQHPF 682 >sp|Q9ZQR3|Y2451_ARATH Leucine-rich repeat receptor-like serine/threonine-protein kinase At2g14510 OS=Arabidopsis thaliana OX=3702 GN=At2g14510 PE=1 SV=1 Length=868 Score = 229 bits (584), Expect = 4e-61, Method: Composition-based stats. Identities = 65/323 (20%), Positives = 126/323 (39%), Gaps = 18/323 (6%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 I R ++ + + + LG+G FG V Sbjct 528 IFIFRRRKSSTRKVIRPSLEMKNRRFKYSEVKEMTNNFEVVLGKGGFGVVYHGFL----- 582 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 E VAVK L ++ +K E+++L ++H +++ G C++ + L L+ E++ Sbjct 583 -NNEQVAVKVLSQSSTQGYKE-FKTEVELLLRVHHVNLVSLVGYCDEGID--LALIYEFM 638 Query 982 PLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDND 1034 G+L+++L + + L A + G+ YLH +HRD+ + N+LL Sbjct 639 ENGNLKEHLSGKRGGSVLNWSSRLKIAIESALGIEYLHIGCQPPMVHRDVKSTNILLGLR 698 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 K+ DFGL+++ G + + V + + + PE + SDV+SFG+ L E Sbjct 699 FEAKLADFGLSRSFLVGSQAH-VSTNVAGTLGYLDPEYYLKNWLTEKSDVYSFGIVLLES 757 Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154 +T + K ++ A+ + + +++ + L C Sbjct 758 ITGQPVIEQSRDKSY-IVEWAKSMLANGDIESIMDPNLHQDYDSSSSWKALELAMLCINP 816 Query 1155 EASFRPTFENLIPILKTVHEKYQ 1177 ++ RP + L E Y Sbjct 817 SSTQRPNMTRVAHELNECLEIYN 839 Score = 209 bits (532), Expect = 2e-54, Method: Composition-based stats. Identities = 78/340 (23%), Positives = 118/340 (35%), Gaps = 68/340 (20%) Query 563 IMRGARASPRTLNLSQLSFH--RVDQKEITQLS-----HLGQGTRTNVYEGRLRVEGSGD 615 I R ++S R + L R E+ +++ LG+G VY G L E Sbjct 530 IFRRRKSSTRKVIRPSLEMKNRRFKYSEVKEMTNNFEVVLGKGGFGVVYHGFLNNE---- 585 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHG 675 +V +KVL S F L+ +V H +L + G Sbjct 586 ----------------------QVAVKVLSQSSTQGYKEFKTEVELLLRVHHVNLVSLVG 623 Query 676 VCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNL 730 C G + ++ E++E+G L L +RG + W ++ +A + A + YL + Sbjct 624 YCDEGIDLALIYEFMENGNLKEHLSGKRGGSVLNWSSRLKIAIESALGIEYLHIGCQPPM 683 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPECL 784 VH +V NILL G KL+D G+ A + +L PE Sbjct 684 VHRDVKSTNILL-------GLRFEAKLADFGLSRSFLVGSQAHVSTNVAGTLGYLDPEYY 736 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS---EKEHFYQRQHRLPEPSCPQL 841 N L+ D + FG LLE QSR S E + P L Sbjct 737 L--KNWLTEKSDVYSFGIVLLESITGQPVIEQSRDKSYIVEWAKSMLANGDIESIMDPNL 794 Query 842 A------------TLTSQCLTYEPTQRPSFRTILRDLTRL 869 L C+ TQRP+ + +L Sbjct 795 HQDYDSSSSWKALELAMLCINPSSTQRPNMTRVAHELNEC 834 >sp|Q55BN8|NEK2_DICDI Probable serine/threonine-protein kinase nek2 OS=Dictyostelium discoideum OX=44689 GN=nek2 PE=1 SV=1 Length=418 Score = 218 bits (556), Expect = 4e-61, Method: Composition-based stats. Identities = 60/273 (22%), Positives = 112/273 (41%), Gaps = 32/273 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG+G FG VS G ++ K + + + + E++IL+ L H++I++ Sbjct 10 LGKGSFGVVS----KIKRKEDGRVLVWKEICYENMQEKEKQLLVNEVNILQKLKHQNIVR 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHA 1016 Y D+ L ++ME+ G L + + + + QI + +H Sbjct 66 YYDRIIDKPSSRLYIIMEHCSGGDLSQLIKKCRNERTYMDEEVIWRTLLQILSALQEIHN 125 Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + +HRD+ N+ LD ++ +K+GDFGLAK + E + ++ +PE + Sbjct 126 RKDGVILHRDIKPGNLFLDENKNIKLGDFGLAKILNESLYAHT----FVGTPYYMSPEQI 181 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 K+ SDVWS G +YE+ T ++ +LT ++ G Sbjct 182 HGLKYNERSDVWSVGCLIYEMATLSPPFEAT---------------NQAQLTSKIQVGRY 226 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 P P + + ++ + RP L+ Sbjct 227 NPIPSQYSEHLSKVISLMINVDPKSRPNVNELL 259 Score = 155 bits (392), Expect = 2e-39, Method: Composition-based stats. Identities = 45/289 (16%), Positives = 101/289 (35%), Gaps = 43/289 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + L LG+G+ V + + + +G + E +++ ++L V Sbjct 1 MDQYEILGALGKGSFGVVSKIKRKEDGRVLVWK-----EICYENMQEKEKQLLV------ 49 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP--ENIMVTEYVEHGPLDVWL---R 700 +++ ++ H ++ + + P ++ E+ G L + R Sbjct 50 -----------NEVNILQKLKHQNIVRYYDRIIDKPSSRLYIIMEHCSGGDLSQLIKKCR 98 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKL 757 ER ++ Q+ SAL + N+ ++H ++ N+ L + IKL Sbjct 99 NERTYMDEEVIWRTLLQILSALQEIHNRKDGVILHRDIKPGNLFLDE-------NKNIKL 151 Query 758 SDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 D G+ +L V +++PE + G + D W G + E+ Sbjct 152 GDFGLAKILNESLYAHTFVGTPYYMSPEQIHG--LKYNERSDVWSVGCLIYEMATLSPPF 209 Query 815 LQSRSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 + ++ +P L+ + S + +P RP+ + Sbjct 210 EATNQAQLTSKIQVGRYNPIPSQYSEHLSKVISLMINVDPKSRPNVNEL 258 >sp|Q13470|TNK1_HUMAN Non-receptor tyrosine-protein kinase TNK1 OS=Homo sapiens OX=9606 GN=TNK1 PE=1 SV=3 Length=666 Score = 225 bits (574), Expect = 4e-61, Method: Composition-based stats. Identities = 99/336 (29%), Positives = 147/336 (44%), Gaps = 27/336 (8%) Query 845 TSQCLTYEPTQRPSFRTI--LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902 + L P + I +P +D P+ + + + + Sbjct 62 ALKRLRSGPKSKNWVYKILGGFAPEHKEPTLPSDSPRHLPEPEGGLKCLIPEGAVCRGEL 121 Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRS--GWKQEIDILRTLYHEHI 959 LG G FG V + G VAVK+L+ GP + +E+ ++ L H H+ Sbjct 122 LGSGCFGVVHRGLWT-LPSGKSVPVAVKSLRVGPEGPMGTELGDFLREVSVMMNLEHPHV 180 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH 1015 ++ G Q LQ+VME PLGSL L P + +A L LF +Q+ MAYL Sbjct 181 LRLHGLVLGQ---PLQMVMELAPLGSLHARLTAPAPTPPLLVALLCLFLRQLAGAMAYLG 237 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 A+ +HRDLA RN+LL + R +K+ DFGL + + Y + P W APE L+ Sbjct 238 ARGLVHRDLATRNLLLASPRTIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRH 297 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 F ASDVW FGVTL+E+ + + + + + LE RLP Sbjct 298 GAFSSASDVWMFGVTLWEMFSGGEE--------------PWAGVPPYLILQRLEDRARLP 343 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 RP C +Y L CW + RP+F +L +L+ Sbjct 344 RPPLCSRALYSLALRCWAPHPADRPSFSHLEGLLQE 379 Score = 187 bits (476), Expect = 2e-48, Method: Composition-based stats. Identities = 76/294 (26%), Positives = 111/294 (38%), Gaps = 46/294 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + + + + LG G V+ G G+ + V +K Sbjct 111 IPEGAVCRGELLGSGCFGVVHRGLW---------------------TLPSGKSVPVAVKS 149 Query 644 LDPSHHDIAL----AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 L F S+M + H H+ +HG+ + G MV E G L L Sbjct 150 LRVGPEGPMGTELGDFLREVSVMMNLEHPHVLRLHGLVL-GQPLQMVMELAPLGSLHARL 208 Query 700 RRERGHVPMAWKMVVA--QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 P+ ++ +QLA A++YL + LVH ++ RN+LLA + IK+ Sbjct 209 TAPAPTPPLLVALLCLFLRQLAGAMAYLGARGLVHRDLATRNLLLA-------SPRTIKV 261 Query 758 SDPGV------GLGAL-SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +D G+ G R W APE L GA S+A D W FG TL E+ Sbjct 262 ADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRHGA--FSSASDVWMFGVTLWEMFSG 319 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTI 862 GE P P + + RLP P L +L +C P RPSF + Sbjct 320 GEEPWAGVPPYLILQRLEDRARLPRPPLCSRALYSLALRCWAPHPADRPSFSHL 373 >sp|Q9XI96|PERK7_ARATH Proline-rich receptor-like protein kinase PERK7 OS=Arabidopsis thaliana OX=3702 GN=PERK7 PE=2 SV=1 Length=699 Score = 226 bits (576), Expect = 4e-61, Method: Composition-based stats. Identities = 80/293 (27%), Positives = 124/293 (42%), Gaps = 49/293 (17%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V G+ +AVK+LKA G R ++ E++I+ ++H H++ Sbjct 342 LGQGGFGYVHKGIL-----PNGKEIAVKSLKAGSGQGERE-FQAEVEIISRVHHRHLVSL 395 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLH---A 1016 G C + G + L LV E++P +L +L S + L A +G+AYLH Sbjct 396 VGYCSNAGGQRL-LVYEFLPNDTLEFHLHGKSGTVMDWPTRLKIALGSAKGLAYLHEDCH 454 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ A N+LLD++ K+ DFGLAK + + + R + APE Sbjct 455 PKIIHRDIKASNILLDHNFEAKVADFGLAKLSQDNNTHVSTR--VMGTFGYLAPEYASSG 512 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL-P 1135 K SDV+SFGV L EL+T L+ A+ +R+ + E GE + P Sbjct 513 KLTEKSDVFSFGVMLLELITGRGPVDLSGDMEDSLVDWARPL--CMRVAQDGEYGELVDP 570 Query 1136 RPDKCPCEVYHLMKNCWETEA------------------SFRPTFENLIPILK 1170 + + E RP ++ L+ Sbjct 571 FLEH-------------QYEPYEMARMVACAAAAVRHSGRRRPKMSQIVRTLE 610 Score = 218 bits (554), Expect = 4e-58, Method: Composition-based stats. Identities = 54/270 (20%), Positives = 96/270 (36%), Gaps = 47/270 (17%) Query 574 LNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 N S ++ + + ++ LGQG V++G L Sbjct 319 FNNSTFTYEELASATQGFSKDRLLGQGGFGYVHKGILPNGK------------------- 359 Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYV 690 + +K L F ++S+V H HL + G C G + ++V E++ Sbjct 360 ------EIAVKSLKAGSGQGEREFQAEVEIISRVHHRHLVSLVGYCSNAGGQRLLVYEFL 413 Query 691 EHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLG 746 + L+ L + G + ++ +A A L+YL ++H ++ NILL Sbjct 414 PNDTLEFHLHGKSGTVMDWPTRLKIALGSAKGLAYLHEDCHPKIIHRDIKASNILLDH-- 471 Query 747 LAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFG 801 + K++D G+ + V +LAPE G L+ D + FG Sbjct 472 -----NFEAKVADFGLAKLSQDNNTHVSTRVMGTFGYLAPEYASSG--KLTEKSDVFSFG 524 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 LLE+ G P+ E + Sbjct 525 VMLLELI-TGRGPVDLSGDMEDSLVDWARP 553 >sp|Q2TA06|AURKA_BOVIN Aurora kinase A OS=Bos taurus OX=9913 GN=AURKA PE=2 SV=1 Length=402 Score = 218 bits (555), Expect = 4e-61, Method: Composition-based stats. Identities = 70/322 (22%), Positives = 122/322 (38%), Gaps = 32/322 (10%) Query 851 YEPTQRPSFRTIL--RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 P RP T + +N + + S + + R LG+G F Sbjct 85 PRPVTRPPSNTQKSKQPQPPAPGNNPEKEVASKQKNEESKKRQWALEDFEIGRPLGKGKF 144 Query 909 GKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRS-GWKQEIDILRTLYHEHIIKYKGCC 966 G V L + ++A+K L KA ++E++I L H +I++ G Sbjct 145 GNVYL----AREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYF 200 Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 D + L++EY PLG++ L + + + ++ ++Y H++ IHRD+ Sbjct 201 HDAT--RVYLILEYAPLGAVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 258 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 N+LL + +KI DFG + P R + + PE ++ D+W Sbjct 259 PENLLLGSAGELKIADFGWSVHAPSSR-----RTTLCGTLDYLPPEMIEGRMHDEKVDLW 313 Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 S GV YE L ++ Q T R++ + PD P Sbjct 314 SLGVLCYEFLVGKPPFEADTY-----------QETYRRISRV-----EFTFPDCVPEGAR 357 Query 1146 HLMKNCWETEASFRPTFENLIP 1167 L+ + S RPT + ++ Sbjct 358 DLISRLLKHNPSQRPTLKEVLE 379 Score = 188 bits (478), Expect = 7e-51, Method: Composition-based stats. Identities = 60/340 (18%), Positives = 119/340 (35%), Gaps = 48/340 (14%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 ++ P PG + + L ++ LG+G NVY Sbjct 99 KQPQPPAPGNNPEKEVASKQKNEESKKRQWAL-------EDFEIGRPLGKGKFGNVYLA- 150 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD---IALAFYETASLMSQ 664 R++ + + LKVL + + + + S Sbjct 151 -----------------------REKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSH 187 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 + H ++ ++G ++ EY G + L++ +LA+ALSY Sbjct 188 LRHPNILRLYGYFHDATRVYLILEYAPLGAVYRELQKL-SKFDEQRTATYITELANALSY 246 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--REERVERIPWLAPE 782 +K ++H ++ N+LL G++ +K++D G + A S R + +L PE Sbjct 247 CHSKRVIHRDIKPENLLL-------GSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPE 299 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQL 841 + G + +D W G E G+ P ++ + E + + P+ Sbjct 300 MIEGRMH--DEKVDLWSLGVLCYEFLV-GKPPFEADTYQETYRRISRVEFTFPDCVPEGA 356 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 L S+ L + P+QRP+ + +L + + Sbjct 357 RDLISRLLKHNPSQRPTLKEVLEHPWIIANSKPSSCQKKE 396 >sp|Q8GY82|CRK45_ARATH Cysteine-rich receptor-like protein kinase 45 OS=Arabidopsis thaliana OX=3702 GN=CRK45 PE=1 SV=1 Length=351 Score = 216 bits (550), Expect = 4e-61, Method: Composition-based stats. Identities = 62/275 (23%), Positives = 109/275 (40%), Gaps = 16/275 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V G+ +AVK L R + E+ IL L H+++I Sbjct 43 VGRGGFGFVYKGRLQ-----NGQEIAVKILSTSSIRTERQ-FHNELIILSKLKHKNLINL 96 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017 G C + + LV E++P SL ++ + I G+ YLH + Sbjct 97 LGFCTKRDQHG--LVYEFMPNSSLDCFILDPHRAAQLNWEMCRNIIDGIARGLRYLHEES 154 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRD+ N+LLD+D KI F LA+ + +G E V + PE ++ Sbjct 155 GLWVVHRDIKPGNILLDSDLKPKIVGFELARTMQQGENAAETTE-IVGTVGYLDPEYIRS 213 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + SDV++FGVT+ +++ + ++ + + + + + R E Sbjct 214 GRVSVKSDVYAFGVTILTIISRRKAWSVDGDSLIKYVRRCWNRGEAIDVIHEVMREEERE 273 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 H+ C + A RP + ++ Sbjct 274 YSISEILRYIHIALLCVDENAERRPNIDKVLHWFS 308 Score = 198 bits (504), Expect = 7e-55, Method: Composition-based stats. Identities = 56/372 (15%), Positives = 113/372 (30%), Gaps = 61/372 (16%) Query 560 NLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEG 619 + + R + S ++ + + +G+G VY+GRL+ Sbjct 8 DTVFRRRKKKSTEFISFFEFDLDTIKAATNDFSELVGRGGFGFVYKGRLQNGQ------- 60 Query 620 KMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR 679 + +K+L S F+ ++S++ H +L + G C + Sbjct 61 ------------------EIAVKILSTSSIRTERQFHNELIILSKLKHKNLINLLGFCTK 102 Query 680 GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQLASALSYLENKN---LVHGN 734 ++ +V E++ + LD ++ + W+M + +A L YL ++ +VH + Sbjct 103 RDQHGLVYEFMPNSSLDCFILDPHRAAQLNWEMCRNIIDGIARGLRYLHEESGLWVVHRD 162 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGA 788 + NILL K+ + A E V + +L PE + G Sbjct 163 IKPGNILLDSDLKP-------KIVGFELARTMQQGENAAETTEIVGTVGYLDPEYIRSG- 214 Query 789 NSLSTAMDKWGFGATLLEICFDG--------------EAPLQSRSPSEKEHFYQRQHRLP 834 +S D + FG T+L I + H R+ Sbjct 215 -RVSVKSDVYAFGVTILTIISRRKAWSVDGDSLIKYVRRCWNRGEAIDVIHEVMREEERE 273 Query 835 EPSCPQLA--TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVF 892 L + C+ +RP+ +L + + Sbjct 274 YSISEILRYIHIALLCVDENAERRPNIDKVLHWFSCFSTPLPDPTFGNRFLVEEETNWPW 333 Query 893 HKRYLKKIRDLG 904 + Sbjct 334 SPSLSPGHSSVT 345 >sp|Q5QNM6|CIPKD_ORYSJ Putative CBL-interacting protein kinase 13 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK13 PE=3 SV=1 Length=511 Score = 221 bits (564), Expect = 4e-61, Method: Composition-based stats. Identities = 71/268 (26%), Positives = 118/268 (44%), Gaps = 26/268 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960 LG+G+F KV Y N TGE VA+K ++ + + + K+EI +LR + H HI+ Sbjct 31 LGQGNFAKV----YHARNVATGEEVAIKVMEKEKIFKSGLTAHIKREIAVLRRVRHPHIV 86 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + + + VMEYV G L + R + A + QQ+ +A+ HA+ Sbjct 87 QLYEVMATK--LRIYFVMEYVRGGELFARVARGRLPEADARRYFQQLVSAVAFCHARGVF 144 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ N+L+D+ +K+ DFGL+ AV +G + + APE L + Sbjct 145 HRDIKPENLLVDDAGDLKVSDFGLS-AVADGMRRDGLFHTFCGTPAYVAPEVLSRRGYDA 203 Query 1081 A-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 A +D+WS GV L+ L+ Q + + + +G+ P Sbjct 204 AGADLWSCGVVLFVLMAGYLPFQD---------------RNLAGMYRKIHKGD-FRCPKW 247 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 E+ L++ T R T E ++ Sbjct 248 FSPELIRLLRGVLVTNPQRRATAEGIME 275 Score = 179 bits (453), Expect = 1e-46, Method: Composition-based stats. Identities = 61/290 (21%), Positives = 101/290 (35%), Gaps = 45/290 (16%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 LGQG VY R G V +KV++ Sbjct 25 FEVGKLLGQGNFAKVYHARNVATGE------------------------EVAIKVMEKEK 60 Query 649 ---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + +++ +V H H+ ++ V V EYV G L + R RG Sbjct 61 IFKSGLTAHIKREIAVLRRVRHPHIVQLYEVMATKLRIYFVMEYVRGGEL--FARVARGR 118 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763 +P A QQL SA+++ + + H ++ N+L+ G +K+SD G+ Sbjct 119 LPEADARRYFQQLVSAVAFCHARGVFHRDIKPENLLVDDAGD-------LKVSDFGLSAV 171 Query 764 LGALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + R+ ++APE L + D W G L + G P Q R+ Sbjct 172 ADGMRRDGLFHTFCGTPAYVAPEVLSRRGYD-AAGADLWSCGVVL-FVLMAGYLPFQDRN 229 Query 820 PSEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + + R P+ P+L L L P +R + I+ + Sbjct 230 LAGMYRKIHKGDFRCPKWFSPELIRLLRGVLVTNPQRRATAEGIMENEWF 279 >sp|Q2VWQ3|STE20_TALMA Serine/threonine-protein kinase pakA OS=Talaromyces marneffei OX=37727 GN=pakA PE=3 SV=1 Length=642 Score = 224 bits (572), Expect = 5e-61, Method: Composition-based stats. Identities = 61/290 (21%), Positives = 119/290 (41%), Gaps = 24/290 (8%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 + + +G+G G V + T + VA+K + D P+ + EI +++ Sbjct 357 PTKKYYNLNKIGQGASGGV----FTAYETNTNKCVAIKQMNLDLQPK-KDLIINEILVMK 411 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 H++I+ + + L +VMEY+ GSL D + + + Q+ ++ G+ Sbjct 412 DSKHKNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMSEGQIAAVCRETLSGLQ 469 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 +LH++ IHRD+ + N+LL D +K+ DFG + ++ R +W APE Sbjct 470 HLHSKGVIHRDIKSDNILLSMDGEIKLTDFGFCAQI---NDSQNKRNTMVGTPYWMAPEV 526 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + ++ D+WS G+ E++ + + L IA ++ + L Sbjct 527 VTRKEYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLIATNGTPKIKDEQNLSPVF 585 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI-LKTVHEKYQGQAP 1181 R + HL + R + +L+ ++ E AP Sbjct 586 R---------DFLHLALR---VDPEKRASAHDLLKHPFMSICEPLNSLAP 623 Score = 180 bits (457), Expect = 4e-46, Method: Composition-based stats. Identities = 58/332 (17%), Positives = 101/332 (30%), Gaps = 51/332 (15%) Query 550 CCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLR 609 P+P R + A L + K+ L+ +GQG V+ Sbjct 329 VARPRPR-------TRQSTAFDVRAKLQAICTPGDPTKKYYNLNKIGQGASGGVF----- 376 Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTH 669 + V +K ++ +M H + Sbjct 377 -------------------TAYETNTNKCVAIKQMNLDLQPKKDLIINEILVMKDSKHKN 417 Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729 + + G + +V EY+E G L + + V ++ S L +L +K Sbjct 418 IVNFLDSYLHGLDLWVVMEYMEGGSLTDVV--TFNIMSEGQIAAVCRETLSGLQHLHSKG 475 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLP 785 ++H ++ NILL+ IKL+D G R V W+APE + Sbjct 476 VIHRDIKSDNILLS-------MDGEIKLTDFGFCAQINDSQNKRNTMVGTPYWMAPEVVT 528 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL----PEPSCPQL 841 +D W G +E+ +GE P + SP + + P Sbjct 529 --RKEYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLIATNGTPKIKDEQNLSPVF 585 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 L +P +R S +L+ Sbjct 586 RDFLHLALRVDPEKRASAHDLLKHPFMSICEP 617 >sp|P53670|LIMK2_RAT LIM domain kinase 2 OS=Rattus norvegicus OX=10116 GN=Limk2 PE=2 SV=1 Length=638 Score = 224 bits (572), Expect = 5e-61, Method: Composition-based stats. Identities = 79/309 (26%), Positives = 131/309 (42%), Gaps = 38/309 (12%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 S + +F L LG+G FG+ T+ TG+++ +K L C + + Sbjct 316 RCSSSYSQQIFRPCDLIHGEVLGKGFFGQ----AIKVTHKATGKVMVMKEL-IRCDEETQ 370 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQL 1000 + E+ ++R+L H +++K+ G +K L L+ EY+ G+L+D+L Q Sbjct 371 KTFLTEVKVMRSLDHPNVLKFIGVLYK--DKKLNLLTEYIEGGTLKDFLRNVDPFPWQQK 428 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG--------- 1051 + FA+ I GMAYLH+ IHRDL + N L+ D+ V + DFGL++ + E Sbjct 429 VRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRPPVEKA 488 Query 1052 --------HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 + R +W APE L + DV+SFG+ L E++ + Sbjct 489 ATKKRTLRKSDRKKRYTVVGNPYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPD 548 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163 + L+ G L + + P CP + L C + E RP F Sbjct 549 CLPRTLDF-----GLNVKLFWEKFV--------PTDCPPAFFPLAAICCKLEPESRPAFS 595 Query 1164 NLIPILKTV 1172 L + + Sbjct 596 KLEDSFEAL 604 Score = 201 bits (512), Expect = 3e-53, Method: Composition-based stats. Identities = 63/345 (18%), Positives = 112/345 (32%), Gaps = 62/345 (18%) Query 553 PQPGETSNLIIMRGARASPRTLN-LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 P P +++ + +L S S ++ LG+G + + Sbjct 294 PGPSSPKEPLLLSRDISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKAT 353 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 G +V+K L + F +M + H ++ Sbjct 354 GK------------------------VMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVL 389 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 GV + + ++TEY+E G L +LR P K+ A+ +AS ++YL + ++ Sbjct 390 KFIGVLYKDKKLNLLTEYIEGGTLKDFLRNVD-PFPWQQKVRFAKGIASGMAYLHSMCII 448 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------------------------GAL 767 H ++ N L+ + ++D G+ Sbjct 449 HRDLNSHNCLI-------KLDKTVVVADFGLSRLIVEERKRPPVEKAATKKRTLRKSDRK 501 Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--FDGEAPLQSRSPSEKEH 825 R V W+APE L G S +D + FG L EI + R+ + Sbjct 502 KRYTVVGNPYWMAPEMLNG--KSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLN 559 Query 826 FY-QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + +P P L + C EP RP+F + L Sbjct 560 VKLFWEKFVPTDCPPAFFPLAAICCKLEPESRPAFSKLEDSFEAL 604 >sp|Q91821|MELK_XENLA Maternal embryonic leucine zipper kinase OS=Xenopus laevis OX=8355 GN=melk PE=1 SV=2 Length=651 Score = 225 bits (573), Expect = 5e-61, Method: Composition-based stats. Identities = 72/274 (26%), Positives = 122/274 (45%), Gaps = 26/274 (9%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 Y + +G G F KV L ++ TGE VA+K + + K EID ++ L Sbjct 12 YYELHETVGTGGFAKVKL----ASHLITGEKVAIKIMDKESLGDDLPRVKTEIDAMKNLS 67 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYL 1014 H+H+ + E K + +V+EY P G L DY+ + + + +F +QI +AY+ Sbjct 68 HQHVCRLYHVIE--TPKKIFMVLEYCPGGELFDYIIAKDRLTEEEARVFFRQIVSAVAYI 125 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H+Q Y HRDL N+L+D D+ +K+ DFGL G +Y+ + + APE ++ Sbjct 126 HSQGYAHRDLKPENLLIDEDQNLKLIDFGLCAKPKGGLDYHLM--TCCGSPAYAAPELIQ 183 Query 1075 EYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + +D+WS GV +Y L+ V+ L + + RG + Sbjct 184 GKAYIGSEADIWSMGVLMYALMCGYLPFDDD---------------NVMVLYKKIMRG-K 227 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P L+ + + R T ++L+ Sbjct 228 YEIPKWLSPGSVLLLSQMMQVDPKKRITVKHLLN 261 Score = 172 bits (436), Expect = 2e-43, Method: Composition-based stats. Identities = 48/319 (15%), Positives = 99/319 (31%), Gaps = 39/319 (12%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH- 648 +G G V + G +V +K++D Sbjct 14 ELHETVGTGGFAKVKLASHLITGE------------------------KVAIKIMDKESL 49 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 D M +SH H+ ++ V + MV EY G L ++ + + Sbjct 50 GDDLPRVKTEIDAMKNLSHQHVCRLYHVIETPKKIFMVLEYCPGGELFDYIIA-KDRLTE 108 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA-- 766 V +Q+ SA++Y+ ++ H ++ N+L+ +KL D G+ Sbjct 109 EEARVFFRQIVSAVAYIHSQGYAHRDLKPENLLIDE-------DQNLKLIDFGLCAKPKG 161 Query 767 ---LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + APE + G A + + D W G + + Sbjct 162 GLDYHLMTCCGSPAYAAPELIQGKAY-IGSEADIWSMGVLMYALMCGYLPFDDDNVMVLY 220 Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 + + ++ +P+ P L SQ + +P +R + + +L + ++ Sbjct 221 KKIMRGKYEIPKWLSPGSVLLLSQMMQVDPKKRITVKHLLNHPWLMHGYSCPVEWQSKYP 280 Query 884 SPASDPTVFHKRYLKKIRD 902 D + + Sbjct 281 LGYIDEDCVTELSVFYKYS 299 >sp|Q9UV51|HOG1_PYRO7 Mitogen-activated protein kinase HOG1 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507 GN=HOG1 PE=3 SV=1 Length=357 Score = 216 bits (550), Expect = 5e-61, Method: Composition-based stats. Identities = 67/293 (23%), Positives = 111/293 (38%), Gaps = 31/293 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VA+K + K P +E+ +L+ L HE++ Sbjct 24 QPVGMGAFGLVC----SARDQLTNQNVAIKKIMKPFSTPVLAKRTYRELKLLKHLKHENV 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHE 1174 L + ER P + L++ + R T + L H+ Sbjct 252 SLPKRERQPLKNKFKNADPSAIDLLERMLVFDPKKRITATEALAHEYLTPYHD 304 Score = 129 bits (324), Expect = 5e-31, Method: Composition-based stats. Identities = 37/231 (16%), Positives = 75/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E D + M + RD+ V +K ++ P +A Y Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAIKKIMKPFSTPVLAKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLKHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q9LGV5|CIPK1_ORYSJ CBL-interacting protein kinase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK1 PE=2 SV=1 Length=461 Score = 219 bits (559), Expect = 5e-61, Method: Composition-based stats. Identities = 66/284 (23%), Positives = 113/284 (40%), Gaps = 28/284 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHI 959 LGEG+FGKV + TG A+K L + + ++EI L+ L H ++ Sbjct 24 TLGEGNFGKVKY----ARHLATGAHFAIKILDRNKILSLRFDDQIRREIGTLKLLKHPNV 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ + + + +V+EYV G L D + + + + QQ+ + ++Y H + Sbjct 80 VRLHEVAASKTK--IYMVLEYVNGGELFDKIAVKGKLSEHEGRRLFQQLIDAVSYCHDKG 137 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL NVL+D +KI DFGL+ + SP + APE L+ + Sbjct 138 VYHRDLKPENVLVDRRGNIKISDFGLSALPQHLGNDGLLHTTCGSPN-YIAPEVLQNRGY 196 Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + SD+WS GV LY +L ++ L + + +G+ P Sbjct 197 DGSLSDIWSCGVILYVMLVGYLPFDD---------------RNLVVLYQKIFKGDT-QIP 240 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 L++ E R + + + Y P Sbjct 241 KWLSPSARDLLRRILEPNPMKRINIAGIKEH-EWFQKDYTPVVP 283 Score = 175 bits (444), Expect = 8e-46, Method: Composition-based stats. Identities = 56/306 (18%), Positives = 95/306 (31%), Gaps = 44/306 (14%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647 LG+G V R G+ +K+LD + Sbjct 20 EIGRTLGEGNFGKVKYARHLATGAHF------------------------AIKILDRNKI 55 Query 648 -HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 + + H ++ +H V + MV EYV G L + +G + Sbjct 56 LSLRFDDQIRREIGTLKLLKHPNVVRLHEVAASKTKIYMVLEYVNGGELFDKI-AVKGKL 114 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + QQL A+SY +K + H ++ N+L+ R G IK+SD G+ Sbjct 115 SEHEGRRLFQQLIDAVSYCHDKGVYHRDLKPENVLVDRRG-------NIKISDFGLSALP 167 Query 767 LS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 ++APE L + D W G L + G P R+ Sbjct 168 QHLGNDGLLHTTCGSPNYIAPEVLQNRGYD-GSLSDIWSCGVILYVMLV-GYLPFDDRNL 225 Query 821 SEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 + +P+ P L + L P +R + I + + Sbjct 226 VVLYQKIFKGDTQIPKWLSPSARDLLRRILEPNPMKRINIAGIKEHEWFQKDYTPVVPYD 285 Query 880 VNPDSP 885 + D+ Sbjct 286 DDDDNY 291 >sp|Q9M3D8|LRK13_ARATH L-type lectin-domain containing receptor kinase I.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK13 PE=1 SV=1 Length=664 Score = 225 bits (573), Expect = 5e-61, Method: Composition-based stats. Identities = 72/299 (24%), Positives = 114/299 (38%), Gaps = 18/299 (6%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 P + +K +G+G FG+V G +AVK L D Q Sbjct 325 YGPHRFSYKSLYKATNGFRKDCRVGKGGFGEVYKGTLPG-----GRHIAVKRLSHDA-EQ 378 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIG 996 + E+ + L H +++ G C + E L LV EY+P GSL YL S Sbjct 379 GMKQFVAEVVTMGNLQHRNLVPLLGYCRRKCE--LLLVSEYMPNGSLDQYLFHEGNPSPS 436 Query 997 LAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 Q + + I ++YLH Q +HRD+ A NV+LD++ ++GDFG+AK G Sbjct 437 WYQRISILKDIASALSYLHTGTKQVVLHRDIKASNVMLDSEFNGRLGDFGMAKFHDRGTN 496 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELI 1112 + + APE + +DV++FG L E++ + P L+ Sbjct 497 L--SATAAVGTIGYMAPELITMGT-SMKTDVYAFGAFLLEVICGRRPVEPELPVGKQYLV 553 Query 1113 GIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 L + + + + V L C RP E ++ L Sbjct 554 KWVYECWKEACLFKTRDPRLGVEFLPEEVEMVLKLGLLCTNAMPESRPAMEQVVQYLNQ 612 Score = 216 bits (551), Expect = 4e-58, Method: Composition-based stats. Identities = 64/308 (21%), Positives = 111/308 (36%), Gaps = 63/308 (20%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + +G+G VY+G L + +K L Sbjct 338 ATNGFRKDCRVGKGGFGEVYKGTLPGGRH-------------------------IAVKRL 372 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 F M + H +L + G C R E ++V+EY+ +G LD +L E Sbjct 373 SHDAEQGMKQFVAEVVTMGNLQHRNLVPLLGYCRRKCELLLVSEYMPNGSLDQYLFHEGN 432 Query 705 HVP-MAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 P ++ + + +ASALSYL + ++H ++ N++L +L D Sbjct 433 PSPSWYQRISILKDIASALSYLHTGTKQVVLHRDIKASNVMLDSEFNG-------RLGDF 485 Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ LS V I ++APE + G S D + FGA LLE+ G P+ Sbjct 486 GMAKFHDRGTNLSATAAVGTIGYMAPELITMGT---SMKTDVYAFGAFLLEVIC-GRRPV 541 Query 816 QSRSPSEKEHFYQRQHRLPEPSC------------------PQLATLTSQCLTYEPTQRP 857 + P K++ + + + +C + L C P RP Sbjct 542 EPELPVGKQYLVKWVYECWKEACLFKTRDPRLGVEFLPEEVEMVLKLGLLCTNAMPESRP 601 Query 858 SFRTILRD 865 + +++ Sbjct 602 AMEQVVQY 609 >sp|Q54YF2|AMPKA_DICDI 5'-AMP-activated serine/threonine-protein kinase catalytic subunit alpha OS=Dictyostelium discoideum OX=44689 GN=snfA PE=2 SV=1 Length=727 Score = 226 bits (577), Expect = 5e-61, Method: Composition-based stats. Identities = 72/275 (26%), Positives = 110/275 (40%), Gaps = 31/275 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK--ADCGPQHRSGWKQEIDILRT 953 + + LG G FGKV L + TG VA+K L + ++EI ++ Sbjct 30 NYRLDKTLGIGSFGKVKL----AEHIRTGVKVAIKILNRTKIKNLKMDEKIRREIQNMKL 85 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012 H HIIK E + + +VMEYV G L +Y+ ++ + + QQ+ G+ Sbjct 86 FRHPHIIKLYEVIETTTD--IFMVMEYVTGGELFEYIVKNGKLLEDESRRLFQQMISGVD 143 Query 1013 YLHAQHYIHRDLAARNVLLDN-DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 Y H +HRDL N+LLD ++ +KI DFGL+ + +G ++ SP + APE Sbjct 144 YCHHHMVVHRDLKPENLLLDPINKCIKIADFGLSNMMQDGD---FLKTSCGSPN-YAAPE 199 Query 1072 CLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 + + DVWS GV LY L L + + Sbjct 200 VISGKLYAGPEVDVWSCGVILYAFLCAKLPFDDESIPM---------------LFKKIRE 244 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 G PD L+K + R T + Sbjct 245 GV-FSIPDFVSPSCADLIKKMLVVDPVKRITIHEI 278 Score = 182 bits (461), Expect = 3e-46, Method: Composition-based stats. Identities = 50/287 (17%), Positives = 92/287 (32%), Gaps = 38/287 (13%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 LG G+ V G ++V +K+L+ + Sbjct 30 NYRLDKTLGIGSFGKVKLAEHIRTG------------------------VKVAIKILNRT 65 Query 648 ---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + + M H H+ ++ V + MV EYV G L ++ + G Sbjct 66 KIKNLKMDEKIRREIQNMKLFRHPHIIKLYEVIETTTDIFMVMEYVTGGELFEYIVKN-G 124 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763 + + QQ+ S + Y + +VH ++ N+LL + IK++D G+ Sbjct 125 KLLEDESRRLFQQMISGVDYCHHHMVVHRDLKPENLLLD------PINKCIKIADFGLSN 178 Query 764 --LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + + APE + G + +D W G L P Sbjct 179 MMQDGDFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSCGVILYAFLCAKLPFDDESIPM 237 Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + + +P+ P A L + L +P +R + I Sbjct 238 LFKKIREGVFSIPDFVSPSCADLIKKMLVVDPVKRITIHEIRNHPWF 284 >sp|Q9FF29|PR5K_ARATH PR5-like receptor kinase OS=Arabidopsis thaliana OX=3702 GN=PR5K PE=1 SV=1 Length=665 Score = 225 bits (573), Expect = 5e-61, Method: Composition-based stats. Identities = 68/316 (22%), Positives = 122/316 (39%), Gaps = 23/316 (7%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 T K LG+G FG V Y +G VAVK LK + Sbjct 317 MLKRYSYTRVKKMTNSFAHVLGKGGFGTV----YKGKLADSGRDVAVKILK--VSEGNGE 370 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQ 999 + E+ + H +I+ G C ++ +++ ++ E++P GSL Y+ + + + Sbjct 371 EFINEVASMSRTSHVNIVSLLGFCYEKNKRA--IIYEFMPNGSLDKYISANMSTKMEWER 428 Query 1000 LLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 L A I G+ YLH + +H D+ +N+L+D + KI DFGLAK E Sbjct 429 LYDVAVGISRGLEYLHNRCVTRIVHFDIKPQNILMDENLCPKISDFGLAKLCK-NKESII 487 Query 1057 VREDGDSPVFWYAPECLKE--YKFYYASDVWSFGVTLYELLTHCDSSQSPPT----KFLE 1110 + APE + + SDV+S+G+ + E++ + + + + Sbjct 488 SMLHMRGTFGYIAPEMFSKNFGAVSHKSDVYSYGMVVLEMIGAKNIEKVEYSGSNNGSMY 547 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 +T + +K ++ + C + S RP +I +L+ Sbjct 548 FPEWVYKDFEKGEITRIFGDSITDEE-EKIAKKLVLVALWCIQMNPSDRPPMIKVIEMLE 606 Query 1171 -TVHEKYQGQAPSVFS 1185 + P +FS Sbjct 607 GNLEALQVPPNPLLFS 622 Score = 211 bits (537), Expect = 3e-56, Method: Composition-based stats. Identities = 60/319 (19%), Positives = 117/319 (37%), Gaps = 61/319 (19%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L + S+ RV + + LG+G VY+G+L G Sbjct 318 LKRYSYTRVKKMTNSFAHVLGKGGFGTVYKGKLADSGRD--------------------- 356 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K+L S + F + MS+ SH ++ + G C + ++ E++ +G L Sbjct 357 ---VAVKILKVSEGNG-EEFINEVASMSRTSHVNIVSLLGFCYEKNKRAIIYEFMPNGSL 412 Query 696 DVWLRRERG-HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGT 751 D ++ + VA ++ L YL N+ +VH ++ +NIL+ Sbjct 413 DKYISANMSTKMEWERLYDVAVGISRGLEYLHNRCVTRIVHFDIKPQNILMDE------- 465 Query 752 SPFIKLSDPGVGLGALSREERV------ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + K+SD G+ ++E + ++APE ++S D + +G +L Sbjct 466 NLCPKISDFGLAKLCKNKESIISMLHMRGTFGYIAPEMFSKNFGAVSHKSDVYSYGMVVL 525 Query 806 EIC---------FDGEAPLQSRSPSEKEHFYQRQH--RL--------PEPSCPQLATLTS 846 E+ + G P +++ R+ E +L + Sbjct 526 EMIGAKNIEKVEYSGSNNGSMYFPEWVYKDFEKGEITRIFGDSITDEEEKIAKKLVLVAL 585 Query 847 QCLTYEPTQRPSFRTILRD 865 C+ P+ RP ++ Sbjct 586 WCIQMNPSDRPPMIKVIEM 604 >sp|Q9TW45|PAR1_CAEEL Serine/threonine-protein kinase par-1 OS=Caenorhabditis elegans OX=6239 GN=par-1 PE=1 SV=1 Length=1192 Score = 232 bits (591), Expect = 5e-61, Method: Composition-based stats. Identities = 76/316 (24%), Positives = 126/316 (40%), Gaps = 29/316 (9%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 + + + + + H K ++ +G+G+F KV L Sbjct 128 SSSGRSHPTSGSSSSHARSTGQSGMSSRSAARRNDQDVHVGKYKLLKTIGKGNFAKVKL- 186 Query 915 CYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 + TG VA+K + P +E+ I++ L H +I+K E E++ Sbjct 187 ---AKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVME--TEQT 241 Query 974 LQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD 1032 L LV+EY G + DYL H + + +QI + YLH+++ IHRDL A N+LLD Sbjct 242 LYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLD 301 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTL 1091 D +KI DFG + G++ + + APE K+ DVWS GV L Sbjct 302 QDMNIKIADFGFSNTFSLGNKL----DTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVIL 357 Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 Y L++ + L E + RG + P + +L+K Sbjct 358 YTLVSGSLPFD---------------GQNLKELRERVLRG-KYRIPFYMSTDCENLLKKF 401 Query 1152 WETEASFRPTFENLIP 1167 R + +N++ Sbjct 402 LVINPQRRSSLDNIMK 417 Score = 197 bits (500), Expect = 6e-50, Method: Composition-based stats. Identities = 55/287 (19%), Positives = 101/287 (35%), Gaps = 40/287 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + L +G+G V + + G V +K++D + Sbjct 169 KYKLLKTIGKGNFAKVKLAKHVITGH------------------------EVAIKIIDKT 204 Query 648 HHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + + + +M Q+ H ++ ++ V +V EY G + +L G Sbjct 205 ALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAH-GR 263 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 + +Q+ SA+ YL +KN++H ++ N+LL + IK++D G Sbjct 264 MKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQ-------DMNIKIADFGFSNT 316 Query 766 ---ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + P+ APE G +D W G L + G P ++ E Sbjct 317 FSLGNKLDTFCGSPPYAAPELFSGKKYD-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKE 374 Query 823 KEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 R +R+P L + L P +R S I++D Sbjct 375 LRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWM 421 >sp|O76411|SCD2_CAEEL ALK tyrosine kinase receptor homolog scd-2 OS=Caenorhabditis elegans OX=6239 GN=scd-2 PE=1 SV=3 Length=1421 Score = 233 bits (593), Expect = 6e-61, Method: Composition-based stats. Identities = 78/287 (27%), Positives = 127/287 (44%), Gaps = 37/287 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA--DCGPQHRSGWKQEIDILRTLYHEHII 960 LG G+FG+V Y +G +AVK + +S + E + T E+++ Sbjct 982 LGRGNFGEVYYGEY------SGVKLAVKMISRTFSASQASQSDFCNEALCMGTFVDENVV 1035 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----------HSIGLAQLLLFAQQICEG 1010 + G D + + +EY+ G L ++ + ++ L+ + G Sbjct 1036 RLIGI--DFEKVPYMIALEYMEGGDLLSFVKECRPNQVSLNPFQLAMSDLIKICCDVAAG 1093 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDR---LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 L Y+HRD+AARN+LL + KI DFG+AK + G EYYR+ P+ W Sbjct 1094 CKCLETFGYVHRDIAARNILLTTRGPQRVAKIADFGMAKEITYGTEYYRINGRTMMPIKW 1153 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 PE + F SD+WSFGV +E+ + L + + + Sbjct 1154 TPPEAFIDGVFTTKSDIWSFGVLCWEVFS--------------LGVVPYPNRRNEEVMLM 1199 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 L G RL P P VY LM++CW+T A+ RP F +++ I + + + Sbjct 1200 LTEGARLEYPYGIPTRVYQLMRDCWKTAAADRPKFVDVVEIFQDIQD 1246 Score = 201 bits (512), Expect = 4e-51, Method: Composition-based stats. Identities = 59/335 (18%), Positives = 103/335 (31%), Gaps = 52/335 (16%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 S + + I + LG+G VY G +++ Sbjct 967 SLPSISRDSIERGRVLGRGNFGEVYYG--------------------------EYSGVKL 1000 Query 640 VLKVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +K++ + F A M ++ + G+ ++ EY+E G L Sbjct 1001 AVKMISRTFSASQASQSDFCNEALCMGTFVDENVVRLIGIDFEKVPYMIALEYMEGGDLL 1060 Query 697 VWLRRERG--------HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 +++ R + M+ + + +A+ LE VH ++ RNILL Sbjct 1061 SFVKECRPNQVSLNPFQLAMSDLIKICCDVAAGCKCLETFGYVHRDIAARNILLT----T 1116 Query 749 EGTSPFIKLSDPGVGLGALSREE-------RVERIPWLAPECLPGGANSLSTAMDKWGFG 801 G K++D G+ E + I W PE G +T D W FG Sbjct 1117 RGPQRVAKIADFGMAKEITYGTEYYRINGRTMMPIKWTPPEAFIDGV--FTTKSDIWSFG 1174 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859 E+ G P +R E RL P ++ L C RP F Sbjct 1175 VLCWEVFSLGVVPYPNRRNEEVMLMLTEGARLEYPYGIPTRVYQLMRDCWKTAAADRPKF 1234 Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894 ++ +Q + + + Sbjct 1235 VDVVEIFQDIQDDPASVGMPFPIHPAVRATFAHSQ 1269 >sp|A9RWC9|M2K1A_PHYPA Mitogen-activated protein kinase kinase 1a OS=Physcomitrium patens OX=3218 GN=MKK1a PE=2 SV=1 Length=352 Score = 216 bits (549), Expect = 6e-61, Method: Composition-based stats. Identities = 68/270 (25%), Positives = 112/270 (41%), Gaps = 22/270 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G G V L + T E A+K + + R QE+ I +++ Sbjct 75 LGKGSGGVVQLV----RHKWTNETYALKVIHMNIEETTRKQIVQELKINHASQCPYVVIC 130 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---HSIGLAQLLLFAQQICEGMAYLH-AQH 1018 + G + +V+EY+ GSL D + I L + +Q+ G+ YLH +H Sbjct 131 YHAFYNNG--LISIVLEYMDGGSLADIMKELEPKCIKEPNLGVVCKQVLLGLMYLHQTRH 188 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ N+L+++ VKI DFG++ + VR+ + +PE + + Sbjct 189 IIHRDIKPSNLLVNHKGEVKISDFGVSAVLANSMA---VRDTFVGTCTYMSPERVLGGTY 245 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP- 1137 + SD+WS G+TL E Q P G +G M L + + P Sbjct 246 GFDSDIWSLGLTLLECALGKYPYQPP--------GSEEGWMNFYELLQTIVDQPPPVAPA 297 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 D+ E + C + + RPT L+ Sbjct 298 DQFSPEFCSFISACLQKDPKCRPTAAELLN 327 Score = 165 bits (417), Expect = 3e-43, Method: Composition-based stats. Identities = 54/323 (17%), Positives = 107/323 (33%), Gaps = 49/323 (15%) Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620 ++ G R +T + + + ++ + LG+G+ V Sbjct 41 MLNKEGIRVVSQTQTSTPAANGNISLSDLETVKVLGKGSGGVV----------------- 83 Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVR 679 R + LKV+ + + + + ++ + Sbjct 84 -------QLVRHKWTNETYALKVIHMNIEETTRKQIVQELKINHASQCPYVVICYHAFYN 136 Query 680 GPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLEN-KNLVHGNVCG 737 +V EY++ G L ++ + VV +Q+ L YL ++++H ++ Sbjct 137 NGLISIVLEYMDGGSLADIMKELEPKCIKEPNLGVVCKQVLLGLMYLHQTRHIIHRDIKP 196 Query 738 RNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSLST 793 N+L+ G +K+SD G + R+ V +++PE + GG Sbjct 197 SNLLVNHKGE-------VKISDFGVSAVLANSMAVRDTFVGTCTYMSPERVLGGTYGFD- 248 Query 794 AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP---------EPSCPQLATL 844 D W G TLLE S +FY+ + + P+ + Sbjct 249 -SDIWSLGLTLLECALGKYPYQPPGSEEGWMNFYELLQTIVDQPPPVAPADQFSPEFCSF 307 Query 845 TSQCLTYEPTQRPSFRTILRDLT 867 S CL +P RP+ +L Sbjct 308 ISACLQKDPKCRPTAAELLNHPF 330 >sp|Q7FAZ3|LERK1_ORYSJ G-type lectin S-receptor-like serine/threonine-protein kinase LECRK1 OS=Oryza sativa subsp. japonica OX=39947 GN=LECRK1 PE=2 SV=1 Length=813 Score = 228 bits (580), Expect = 7e-61, Method: Composition-based stats. Identities = 67/274 (24%), Positives = 112/274 (41%), Gaps = 14/274 (5%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G G V + D +AVK + P+ + E++ + +H+++++ Sbjct 529 LGAGASGVVYKGQLE---DELKTNIAVKKIDK-LQPETEKEFMVEVETIGQTFHKNLVRL 584 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH---AQH 1018 G C + E+ LV E++ G L L +S + A + G+ YLH ++ Sbjct 585 LGFCNEGAER--LLVYEFMTNGPLNRLLFDNSRPHWNTRVHIALGVARGLLYLHDECSKQ 642 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IH D+ +N+LLD++ + KI DFGLAK + R + APE K Sbjct 643 IIHCDIKPQNILLDDNLVAKISDFGLAKLLLTNQT--RTNTGIRGTRGYVAPEWFKNIGI 700 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI--GIAQGQMTVLRLTELLERGERLPR 1136 DV+SFGV L EL+ + + + I A R+ L+E + Sbjct 701 STKVDVYSFGVILLELVCCRRNVELEVVDEEQTIVTYWANDCYRSGRIDLLVEGDDEAIY 760 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 K + C + + S RP + +L Sbjct 761 NIKKVERFVTVALWCLQEDPSMRPNMLKVTQMLD 794 Score = 215 bits (547), Expect = 1e-56, Method: Composition-based stats. Identities = 65/334 (19%), Positives = 121/334 (36%), Gaps = 61/334 (18%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 N+ + + + S L L ++ +++ LG G VY+G+L E + Sbjct 494 KKNIPLSQASSKSQ--LPLKTFTYKELEKATAGFHEILGAGASGVVYKGQLEDELKTN-- 549 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 + +K +D + F + Q H +L + G C Sbjct 550 ---------------------IAVKKIDKLQPETEKEFMVEVETIGQTFHKNLVRLLGFC 588 Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGN 734 G E ++V E++ +GPL+ L ++ +A +A L YL +K ++H + Sbjct 589 NEGAERLLVYEFMTNGPLNRLLFDN-SRPHWNTRVHIALGVARGLLYLHDECSKQIIHCD 647 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGAN 789 + +NILL + K+SD G+ L+ + R ++APE Sbjct 648 IKPQNILLD-------DNLVAKISDFGLAKLLLTNQTRTNTGIRGTRGYVAPEWFKNIG- 699 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK------EHFYQRQHRLP--------- 834 +ST +D + FG LLE+ E+ + R R+ Sbjct 700 -ISTKVDVYSFGVILLELVCCRRNVELEVVDEEQTIVTYWANDCYRSGRIDLLVEGDDEA 758 Query 835 ---EPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + T+ CL +P+ RP+ + + Sbjct 759 IYNIKKVERFVTVALWCLQEDPSMRPNMLKVTQM 792 >sp|O81472|MP3K2_ARATH Mitogen-activated protein kinase kinase kinase 9 OS=Arabidopsis thaliana OX=3702 GN=MEKK2 PE=1 SV=1 Length=773 Score = 227 bits (578), Expect = 7e-61, Method: Composition-based stats. Identities = 76/278 (27%), Positives = 122/278 (44%), Gaps = 34/278 (12%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQ---EIDILR 952 +K + L +G FG V G+ AVK + D G Q + +Q EI +L Sbjct 501 WQKGQLLRQGSFGSVYEAI-----SEDGDFFAVKEVSLLDQGSQAQECIQQLEGEIALLS 555 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 L H++I++Y+G D+ +L + +E V GSL + R+ I + + L+ +QI +G+ Sbjct 556 QLEHQNILRYRG--TDKDGSNLYIFLELVTQGSLLELYRRYQIRDSLISLYTKQILDGLK 613 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 YLH + +IHRD+ +L+D + VK+ DFGLAK R +FW APE Sbjct 614 YLHHKGFIHRDIKCATILVDANGTVKLADFGLAKVSKLNDIKSRKE-----TLFWMAPEV 668 Query 1073 LKEY---KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 + + +D+WS G T+ E+ T I + + + Sbjct 669 INRKDNDGYRSPADIWSLGCTVLEMCTG---------------QIPYSDLEPVEALFRIR 713 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 RG PD + H + C + RPT L+ Sbjct 714 RGTLPEVPDTLSLDARHFILKCLKLNPEERPTATELLN 751 Score = 181 bits (459), Expect = 1e-45, Method: Composition-based stats. Identities = 61/283 (22%), Positives = 100/283 (35%), Gaps = 37/283 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + L QG+ +VYE +E + D+ + Sbjct 503 KGQLLRQGSFGSVYEAISEDGDFFAVKEVSLLDQGSQA--------------------QE 542 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 +L+SQ+ H ++ G G + E V G L RR + + Sbjct 543 CIQQLEGEIALLSQLEHQNILRYRGTDKDGSNLYIFLELVTQGSLLELYRRYQIRDSLIS 602 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--GALS 768 +Q+ L YL +K +H ++ IL+ + +KL+D G+ Sbjct 603 L--YTKQILDGLKYLHHKGFIHRDIKCATILVD-------ANGTVKLADFGLAKVSKLND 653 Query 769 REERVERIPWLAPECLPGGANS-LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 + R E + W+APE + N + D W G T+LE+C G+ P P E F Sbjct 654 IKSRKETLFWMAPEVINRKDNDGYRSPADIWSLGCTVLEMC-TGQIPYSDLEPVEAL-FR 711 Query 828 QRQHRLPEPSCPQLAT---LTSQCLTYEPTQRPSFRTILRDLT 867 R+ LPE +CL P +RP+ +L Sbjct 712 IRRGTLPEVPDTLSLDARHFILKCLKLNPEERPTATELLNHPF 754 >sp|Q6P3R8|NEK5_HUMAN Serine/threonine-protein kinase Nek5 OS=Homo sapiens OX=9606 GN=NEK5 PE=1 SV=1 Length=708 Score = 226 bits (575), Expect = 7e-61, Method: Composition-based stats. Identities = 65/281 (23%), Positives = 122/281 (43%), Gaps = 31/281 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961 +G+G FGK L + +K + + P Q + K+E+ +L + H +I+ Sbjct 10 IGQGAFGKAYL----AKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKHPNIVA 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018 + ++ G L +VMEY G L + R Q+L + QI G+ ++H + Sbjct 66 FFNSFQENG--RLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRK 123 Query 1019 YIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRD+ A+N+ L + +V K+GDFG+A+ + E R ++ +PE + Sbjct 124 ILHRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELART---CIGTPYYLSPEICQNKP 180 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + +D+WS G LYEL T + + +L + + P Sbjct 181 YNNKTDIWSLGCVLYELCTLKHPFE---------------GNNLQQLVLKICQAHFAPIS 225 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKY 1176 E++ L+ ++ RP+ +++ P L+ + KY Sbjct 226 PGFSRELHSLISQLFQVSPRDRPSINSILKRPFLENLIPKY 266 Score = 166 bits (421), Expect = 3e-41, Method: Composition-based stats. Identities = 46/283 (16%), Positives = 94/283 (33%), Gaps = 36/283 (13%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + + +GQG Y + + + + ++ P+ Sbjct 1 MDKYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPI------------------ 42 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 A + L+ ++ H ++ +V EY + G L + R+RG Sbjct 43 ----QEKEASKKEVILLEKMKHPNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGV 98 Query 706 V-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + Q++ L ++ ++ ++H ++ +NI L++ G+ KL D G+ Sbjct 99 LFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLSKNGM------VAKLGDFGIAR 152 Query 765 GALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 + + +L+PE + D W G L E+C + Sbjct 153 VLNNSMELARTCIGTPYYLSPEICQN--KPYNNKTDIWSLGCVLYELCTLKHPFEGNNLQ 210 Query 821 SEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 Q + +L +L SQ P RPS +I Sbjct 211 QLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSINSI 253 >sp|C0LGT1|Y5129_ARATH Probable LRR receptor-like serine/threonine-protein kinase At5g10290 OS=Arabidopsis thaliana OX=3702 GN=At5g10290 PE=1 SV=1 Length=613 Score = 223 bits (569), Expect = 7e-61, Method: Composition-based stats. Identities = 70/295 (24%), Positives = 112/295 (38%), Gaps = 20/295 (7%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 + LG+G FGKV VAVK L P + +++ Sbjct 280 WRELQLATDNFSEKNVLGQGGFGKVYKGVL-----PDNTKVAVKRLTDFESPGGDAAFQR 334 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLL 1001 E++++ H ++++ G C Q E+ LV ++ SL L + Sbjct 335 EVEMISVAVHRNLLRLIGFCTTQTER--LLVYPFMQNLSLAHRLREIKAGDPVLDWETRK 392 Query 1002 LFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 A G YLH IHRD+ A NVLLD D +GDFGLAK V V Sbjct 393 RIALGAARGFEYLHEHCNPKIIHRDVKAANVLLDEDFEAVVGDFGLAKLV--DVRRTNVT 450 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIA 1115 + APE L K +DV+ +G+ L EL+T D S+ + L+ Sbjct 451 TQVRGTMGHIAPEYLSTGKSSERTDVFGYGIMLLELVTGQRAIDFSRLEEEDDVLLLDHV 510 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + RL ++++ + + + C + RP ++ +L+ Sbjct 511 KKLEREKRLGAIVDKNLDGEYIKEEVEMMIQVALLCTQGSPEDRPVMSEVVRMLE 565 Score = 187 bits (475), Expect = 1e-48, Method: Composition-based stats. Identities = 65/362 (18%), Positives = 113/362 (31%), Gaps = 67/362 (19%) Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + ++ + ++ + LGQG VY+G L Sbjct 274 QLKRFAWRELQLATDNFSEKNVLGQGGFGKVYKGVLPDN--------------------- 312 Query 633 RGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +V +K L D AF ++S H +L + G C E ++V +++ Sbjct 313 ----TKVAVKRLTDFESPGGDAAFQREVEMISVAVHRNLLRLIGFCTTQTERLLVYPFMQ 368 Query 692 HGPLDVWLRR---ERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745 + L LR + + +A A YL ++H +V N+LL Sbjct 369 NLSLAHRLREIKAGDPVLDWETRKRIALGAARGFEYLHEHCNPKIIHRDVKAANVLLDED 428 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800 A + D G+ R V + +APE L G + S D +G+ Sbjct 429 FEAV-------VGDFGLAKLVDVRRTNVTTQVRGTMGHIAPEYLSTGKS--SERTDVFGY 479 Query 801 GATLLEICFDGEAPLQSRSPSEK-------EHFYQRQHRL------------PEPSCPQL 841 G LLE+ A SR E +R+ RL + + Sbjct 480 GIMLLELVTGQRAIDFSRLEEEDDVLLLDHVKKLEREKRLGAIVDKNLDGEYIKEEVEMM 539 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901 + C P RP ++R L + + + +R+ Sbjct 540 IQVALLCTQGSPEDRPVMSEVVRMLEGEGLAERWEEWQNVEVTRRHEFERLQRRFDWGED 599 Query 902 DL 903 + Sbjct 600 SM 601 >sp|Q9S7I6|RPK2_ARATH LRR receptor-like serine/threonine-protein kinase RPK2 OS=Arabidopsis thaliana OX=3702 GN=RPK2 PE=1 SV=1 Length=1151 Score = 231 bits (590), Expect = 7e-61, Method: Composition-based stats. Identities = 76/278 (27%), Positives = 110/278 (40%), Gaps = 17/278 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG Y +VA+K L Q + EI L L H +++ Sbjct 880 IGNGGFG----ATYKA-EISQDVVVAIKRLSIG-RFQGVQQFHAEIKTLGRLRHPNLVTL 933 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQ---H 1018 G E + LV Y+P G+L ++ R + L A I +AYLH Q Sbjct 934 IGY--HASETEMFLVYNYLPGGNLEKFIQERSTRDWRVLHKIALDIARALAYLHDQCVPR 991 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRD+ N+LLD+D + DFGLA+ + G + APE + Sbjct 992 VLHRDVKPSNILLDDDCNAYLSDFGLARLL--GTSETHATTGVAGTFGYVAPEYAMTCRV 1049 Query 1079 YYASDVWSFGVTLYELLTHC---DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 +DV+S+GV L ELL+ D S ++ A + R E G Sbjct 1050 SDKADVYSYGVVLLELLSDKKALDPSFVSYGNGFNIVQWACMLLRQGRAKEFFTAGLWDA 1109 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 P EV HL C S RPT + ++ LK + Sbjct 1110 GPHDDLVEVLHLAVVCTVDSLSTRPTMKQVVRRLKQLQ 1147 Score = 190 bits (483), Expect = 7e-48, Method: Composition-based stats. Identities = 47/234 (20%), Positives = 83/234 (35%), Gaps = 43/234 (18%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + +G G Y+ + Q++ V +K L Sbjct 873 NFNASNLIGNGGFGATYKAEI-------------------------SQDVVVAIKRLSIG 907 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 F+ + ++ H +L + G E +V Y+ G L+ ++ +ER Sbjct 908 RFQGVQQFHAEIKTLGRLRHPNLVTLIGYHASETEMFLVYNYLPGGNLEKFI-QERSTRD 966 Query 708 MAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 +A +A AL+YL ++ ++H +V NILL A LSD G+ Sbjct 967 WRVLHKIALDIARALAYLHDQCVPRVLHRDVKPSNILLDDDCNAY-------LSDFGLAR 1019 Query 765 GALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 + E ++APE +S D + +G LLE+ D +A Sbjct 1020 LLGTSETHATTGVAGTFGYVAPEYAMTC--RVSDKADVYSYGVVLLELLSDKKA 1071 >sp|Q25AG3|LERK3_ORYSI G-type lectin S-receptor-like serine/threonine-protein kinase LECRK3 OS=Oryza sativa subsp. indica OX=39946 GN=LECRK3 PE=3 SV=2 Length=811 Score = 228 bits (580), Expect = 7e-61, Method: Composition-based stats. Identities = 70/288 (24%), Positives = 116/288 (40%), Gaps = 14/288 (5%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G G V D G +AVK ++ + + + E+ + +H ++++ Sbjct 527 LGTGASGVVYKGQLQ---DEFGINIAVKKIEK-LQQEAQKEFLVEVQTIGQTFHRNLVRL 582 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH---AQH 1018 G C + E+ LV E++ GSL +L + + + A + G+ YLH + Sbjct 583 LGFCNEGTER--LLVYEFMSNGSLNTFLFSDTHPHWSLRVQVALGVARGLLYLHEECNKQ 640 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IH D+ +N+LLD++ KI DFGLAK +P + + APE K Sbjct 641 IIHCDMKPQNILLDDNFAAKISDFGLAKLLPVNQT--QTNTGIRGTRGYVAPEWFKNIGI 698 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPR 1136 DV+SFGV L EL+ + + + L A R+ L+ + Sbjct 699 TSKVDVYSFGVILLELVCCRKNVELEVLDEEQTILTYWANDCYKCGRIDLLVAGDDEAIF 758 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVF 1184 K + C + E S RPT + +L + PS + Sbjct 759 NIKKVERFVAVALWCLQEEPSMRPTMLKVTQMLDGAVQIPTPPDPSSY 806 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 77/408 (19%), Positives = 140/408 (34%), Gaps = 75/408 (18%) Query 486 TVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCF 545 TV + S+ ++D + + G F S L L ++ G C Sbjct 430 TVLIKVPRSTNSPSVFSSGSSKWKEDKKYWILGSSLLFGS-SVLVNFLLISVMLFGTYCS 488 Query 546 SLRR--CCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603 R L QP S L P+ S+L +E+ LG G V Sbjct 489 ITSRKKIQLSQPSNKSGL--------PPKIFTYSELEKATGGFQEV-----LGTGASGVV 535 Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663 Y+G+L+ E + + +K ++ + F + Sbjct 536 YKGQLQDEF-----------------------GINIAVKKIEKLQQEAQKEFLVEVQTIG 572 Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723 Q H +L + G C G E ++V E++ +G L+ +L H + ++ VA +A L Sbjct 573 QTFHRNLVRLLGFCNEGTERLLVYEFMSNGSLNTFLF-SDTHPHWSLRVQVALGVARGLL 631 Query 724 YLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ER 775 YL NK ++H ++ +NILL + K+SD G+ + + Sbjct 632 YLHEECNKQIIHCDMKPQNILLD-------DNFAAKISDFGLAKLLPVNQTQTNTGIRGT 684 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 ++APE +++ +D + FG LLE+ + E+ + + Sbjct 685 RGYVAPEWFKNIG--ITSKVDVYSFGVILLELVCCRKNVELEVLDEEQTILTYWANDCYK 742 Query 836 P------------------SCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + + CL EP+ RP+ + + Sbjct 743 CGRIDLLVAGDDEAIFNIKKVERFVAVALWCLQEEPSMRPTMLKVTQM 790 >sp|Q9MAM1|CIPK9_ARATH CBL-interacting serine/threonine-protein kinase 9 OS=Arabidopsis thaliana OX=3702 GN=CIPK9 PE=1 SV=2 Length=447 Score = 219 bits (557), Expect = 8e-61, Method: Composition-based stats. Identities = 64/276 (23%), Positives = 117/276 (42%), Gaps = 27/276 (10%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRT 953 + R LGEG F KV N TG+ A+K L + +H+ K+EI ++ Sbjct 18 NYEMGRTLGEGSFAKVKY----AKNTVTGDQAAIKILDREKVFRHKMVEQLKREISTMKL 73 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012 + H ++++ + + + +V+E V G L D + + + + + QQ+ + Sbjct 74 IKHPNVVEIIEVMASKTK--IYIVLELVNGGELFDKIAQQGRLKEDEARRYFQQLINAVD 131 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Y H++ HRDL N++LD + ++K+ DFGL+ + E + +P + APE Sbjct 132 YCHSRGVYHRDLKPENLILDANGVLKVSDFGLSAFSRQVREDGLLHTACGTPN-YVAPEV 190 Query 1073 LKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 L + + A+DVWS GV L+ L+ P ++ L + + + Sbjct 191 LSDKGYDGAAADVWSCGVILFVLMAGYLPFDEP---------------NLMTLYKRICKA 235 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 E P ++K E R + L+ Sbjct 236 E-FSCPPWFSQGAKRVIKRILEPNPITRISIAELLE 270 Score = 165 bits (418), Expect = 2e-42, Method: Composition-based stats. Identities = 48/290 (17%), Positives = 90/290 (31%), Gaps = 42/290 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 LG+G+ V + V G + +K+LD Sbjct 18 NYEMGRTLGEGSFAKVKYAKNTVTGD------------------------QAAIKILDRE 53 Query 648 H---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 H + S M + H ++ + V + +V E V G L + ++G Sbjct 54 KVFRHKMVEQLKREISTMKLIKHPNVVEIIEVMASKTKIYIVLELVNGGELFDKI-AQQG 112 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + QQL +A+ Y ++ + H ++ N++L + +K+SD G+ Sbjct 113 RLKEDEARRYFQQLINAVDYCHSRGVYHRDLKPENLILD-------ANGVLKVSDFGLSA 165 Query 765 GALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + ++APE L A D W G L + + Sbjct 166 FSRQVREDGLLHTACGTPNYVAPEVLSDKGYD-GAAADVWSCGVILFVLMAGYLPFDEPN 224 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + + + + P + + L P R S +L D Sbjct 225 LMTLYKRICKAEFSCPPWFSQGAKRVIKRILEPNPITRISIAELLEDEWF 274 >sp|Q5ZJH6|ULK3_CHICK Serine/threonine-protein kinase ULK3 OS=Gallus gallus OX=9031 GN=ULK3 PE=2 SV=1 Length=468 Score = 219 bits (558), Expect = 8e-61, Method: Composition-based stats. Identities = 70/267 (26%), Positives = 109/267 (41%), Gaps = 26/267 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHII 960 LG G + V T E+VAVK + K EI+IL+T+ H HI+ Sbjct 19 RLGTGTYATVYKAYGK---RDTREVVAVKCVSKRSLNRASVENLLTEIEILKTIRHPHIV 75 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + K D + L+ME+ G L ++ R + +F QQ+ + +LH + Sbjct 76 ELKDFQWDSDH--IYLIMEFCAGGDLSRFIRMRRILPEKVARIFLQQLACALKFLHDHNI 133 Query 1020 IHRDLAARNVLLD--NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 H DL +N+LL + +K+ DFG A+ + E + +R + APE + + Sbjct 134 SHLDLKPQNILLSTPENPQLKLADFGFAQYMSPWDEKHVLR----GSPLYMAPEMVCRQQ 189 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + D+WS GV LYE L S LE +R +E R P Sbjct 190 YDARVDLWSVGVILYEALFGRPPFASRSFAELE---------EKIRSDRAIELPSRPPLS 240 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFEN 1164 C L++ E + R +FE Sbjct 241 PDC----RDLLQRLLERDPLKRISFEE 263 Score = 185 bits (469), Expect = 5e-49, Method: Composition-based stats. Identities = 64/302 (21%), Positives = 104/302 (34%), Gaps = 41/302 (14%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 LG GT VY+ G+ +E+ V +K + Sbjct 14 FVLTERLGTGTYATVYKA----------------------YGKRDTREV-VAVKCVSKRS 50 Query 649 HDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 + A ++ + H H+ + ++ E+ G L ++R R + Sbjct 51 LNRASVENLLTEIEILKTIRHPHIVELKDFQWDSDHIYLIMEFCAGGDLSRFIRMRRI-L 109 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 P + QQLA AL +L + N+ H ++ +NILL+ +P +KL+D G Sbjct 110 PEKVARIFLQQLACALKFLHDHNISHLDLKPQNILLS-----TPENPQLKLADFGFAQYM 164 Query 767 LS-REERV--ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 E+ V ++APE + +D W G L E F G P SRS +E Sbjct 165 SPWDEKHVLRGSPLYMAPEMV--CRQQYDARVDLWSVGVILYEALF-GRPPFASRSFAEL 221 Query 824 EHFYQRQHRLP----EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 E + + P P L + L +P +R SF H Sbjct 222 EEKIRSDRAIELPSRPPLSPDCRDLLQRLLERDPLKRISFEEFFAHPFVDMEHMPGPESF 281 Query 880 VN 881 Sbjct 282 CK 283 >sp|O94168|SNF1_CANTR Carbon catabolite-derepressing protein kinase OS=Candida tropicalis OX=5482 GN=SNF1 PE=3 SV=1 Length=619 Score = 223 bits (569), Expect = 8e-61, Method: Composition-based stats. Identities = 76/292 (26%), Positives = 116/292 (40%), Gaps = 31/292 (11%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 + + I+ LGEG FGKV L + GTG+ VA+K + + Sbjct 35 QPIPIDPNVNPANRIGRYQIIKTLGEGSFGKVKL----AQHVGTGQKVALKIINRKTLAK 90 Query 940 HRSG--WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIG 996 ++EI LR L H HIIK + + E + +V+E+ L DY+ R + Sbjct 91 SDMQGRVEREISYLRLLRHPHIIKLYDVIKSKDE--IIMVIEFA-GKELFDYIVQRGKMP 147 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 + F QQI + Y H +HRDL N+LLD+ VKI DFGL+ + +G+ Sbjct 148 EDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLLLDDQLNVKIADFGLSNIMTDGN---F 204 Query 1057 VREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 ++ SP + APE + + DVWS GV LY +L Sbjct 205 LKTSCGSPN-YAAPEVISGKLYAGPEVDVWSSGVILYVMLCGRLPFDDEF---------- 253 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + L + + G P+ HL+ R T ++ Sbjct 254 -----IPALFKKISNGV-YTLPNYLSPGAKHLLTRMLVVNPLNRITIHEIME 299 Score = 179 bits (454), Expect = 7e-46, Method: Composition-based stats. Identities = 58/315 (18%), Positives = 107/315 (34%), Gaps = 44/315 (14%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 A+ P N++ +R+ + +I LG+G+ V Sbjct 34 AQPIPIDPNVNPA--NRIGRYQII--KTLGEGSFGKV----------------------- 66 Query 627 LVPGRDRGQELRVVLKVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 + G +V LK+++ D+ S + + H H+ ++ V E Sbjct 67 -KLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHPHIIKLYDVIKSKDEI 125 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 IMV E+ L ++ +RG +P QQ+ +A+ Y +VH ++ N+LL Sbjct 126 IMVIEFA-GKELFDYI-VQRGKMPEDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLLLD 183 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGF 800 +K++D G+ + + APE + G + +D W Sbjct 184 DQL-------NVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYA-GPEVDVWSS 235 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 G L + P+ + + LP P L ++ L P R + Sbjct 236 GVILYVMLCGRLPFDDEFIPALFKKISNGVYTLPNYLSPGAKHLLTRMLVVNPLNRITIH 295 Query 861 TILRDLTRLQPHNLA 875 I+ D Q Sbjct 296 EIMEDEWFKQDMPDY 310 >sp|Q5JLD8|CIPK8_ORYSJ CBL-interacting protein kinase 8 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK8 PE=2 SV=1 Length=446 Score = 218 bits (556), Expect = 8e-61, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 115/268 (43%), Gaps = 29/268 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959 +GEG F KV N +GE VA+K + +H+ K+EI I++ + H ++ Sbjct 18 TIGEGTFAKVKF----AQNTESGESVAMKVVDRSSILKHKMADQIKREISIMKLVRHPNV 73 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ + K + +++E++ G L D + RH + A + QQ+ +G+ + H++ Sbjct 74 VRLHEVLASR--KKIFIILEFITGGELFDKIIRHGRLNEADARRYFQQLIDGVDFCHSKG 131 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N+LLD+ +KI DFGL+ +G R + APE L + Sbjct 132 VYHRDLKPENLLLDSQGNLKISDFGLSAWPAQGGALLRTT---CGTPNYVAPEVLSHKGY 188 Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 A +D WS GV LY LL P ++L + G++ + P Sbjct 189 DGALADTWSCGVILYVLLAG-----YLPFDEVDLTTL-YGKIESAEYS----------FP 232 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165 P L+ + R E + Sbjct 233 AWFPNGAKSLIHRILDPNPDKRIRIEEI 260 Score = 170 bits (430), Expect = 4e-44, Method: Composition-based stats. Identities = 59/333 (18%), Positives = 103/333 (31%), Gaps = 44/333 (13%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 + RV + E+ +G+GT V ++ V Sbjct 6 ALRRVGKYEV--GRTIGEGTFAKV------------------------KFAQNTESGESV 39 Query 640 VLKVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +KV+D S H +A S+M V H ++ +H V + ++ E++ G L Sbjct 40 AMKVVDRSSILKHKMADQIKREISIMKLVRHPNVVRLHEVLASRKKIFIILEFITGGELF 99 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 + R G + A QQL + + +K + H ++ N+LL G +K Sbjct 100 DKIIRH-GRLNEADARRYFQQLIDGVDFCHSKGVYHRDLKPENLLLDSQG-------NLK 151 Query 757 LSDPGV----GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 +SD G+ G ++APE L D W G L + G Sbjct 152 ISDFGLSAWPAQGGALLRTTCGTPNYVAPEVLSHKGYD-GALADTWSCGVILY-VLLAGY 209 Query 813 APLQSRSPSEKE-HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P + ++ P +L + L P +R I D + Sbjct 210 LPFDEVDLTTLYGKIESAEYSFPAWFPNGAKSLIHRILDPNPDKRIRIEEIRNDEWFKKN 269 Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 + + + F L Sbjct 270 YEPTREIESEEVNLDDVNAAFDDPEEDADHTLD 302 >sp|Q5RDH5|AAPK1_PONAB 5'-AMP-activated protein kinase catalytic subunit alpha-1 (Fragment) OS=Pongo abelii OX=9601 GN=PRKAA1 PE=2 SV=2 Length=554 Score = 222 bits (565), Expect = 8e-61, Method: Composition-based stats. Identities = 77/274 (28%), Positives = 111/274 (41%), Gaps = 30/274 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953 + LG G FGKV + ++ TG VAVK L ++EI L+ Sbjct 21 HYILGDTLGVGTFGKVKVG----KHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKL 76 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012 H HIIK + + +VMEYV G L DY+ ++ + + QQI G+ Sbjct 77 FRHPHIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVD 134 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE Sbjct 135 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 190 Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + D+WS GV LY LL V L + + G Sbjct 191 ISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDH---------------VPTLFKKICDG 235 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P V L+K+ + + R T +++ Sbjct 236 IFYT-PQYLNPSVISLLKHMLQVDPMKRATIKDI 268 Score = 182 bits (462), Expect = 2e-47, Method: Composition-based stats. Identities = 54/298 (18%), Positives = 94/298 (32%), Gaps = 39/298 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 Q RV LG GT V G+ + G Sbjct 10 KQKHDGRVRIGHYILGDTLGVGTFGKVKVGKHELTGH----------------------- 46 Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +V +K+L+ D+ + H H+ ++ V + MV EYV G Sbjct 47 -KVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGG 105 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L ++ + G + + QQ+ S + Y +VH ++ N+LL Sbjct 106 ELFDYICKN-GRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD-------AHM 157 Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ E + APE + G + +D W G L + Sbjct 158 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSSGVILYALLCG 216 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 P+ + P+ P + +L L +P +R + + I Sbjct 217 TLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWF 274 >sp|Q9SGP2|HSL1_ARATH Receptor-like protein kinase HSL1 OS=Arabidopsis thaliana OX=3702 GN=HSL1 PE=1 SV=1 Length=996 Score = 230 bits (586), Expect = 8e-61, Method: Composition-based stats. Identities = 70/290 (24%), Positives = 121/290 (42%), Gaps = 29/290 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-------KADCGPQ-------HRSGWKQEI 948 +G G GKV GE VAVK L DC P+ ++ E+ Sbjct 682 IGAGASGKVYKVVL-----TNGETVAVKRLWTGSVKETGDCDPEKGYKPGVQDEAFEAEV 736 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQ 1005 + L + H++I+K CC + K LV EY+P GSL D L +G Sbjct 737 ETLGKIRHKNIVKLWCCCSTRDCK--LLVYEYMPNGSLGDLLHSSKGGMLGWQTRFKIIL 794 Query 1006 QICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 EG++YLH +HRD+ + N+L+D D ++ DFG+AKAV + + Sbjct 795 DAAEGLSYLHHDSVPPIVHRDIKSNNILIDGDYGARVADFGVAKAVDLTGKAPKSMSVIA 854 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 + APE + SD++SFGV + E++T P +L+ + Sbjct 855 GSCGYIAPEYAYTLRVNEKSDIYSFGVVILEIVTRKRPV-DPELGEKDLVKWVCSTLDQK 913 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + +++ ++ ++ ++ C RP+ ++ +L+ + Sbjct 914 GIEHVIDPKLDSCFKEEIS-KILNVGLLCTSPLPINRPSMRRVVKMLQEI 962 Score = 186 bits (471), Expect = 1e-46, Method: Composition-based stats. Identities = 55/325 (17%), Positives = 110/325 (34%), Gaps = 56/325 (17%) Query 579 LSFHRVDQKE------ITQLSHLGQGTRTNVYEGRLRVEGSGDPEE---GKMDDEDPLVP 629 +SFH++ E + + + +G G VY+ L + + G + + P Sbjct 660 MSFHKLGFSEHEILESLDEDNVIGAGASGKVYKVVLTNGETVAVKRLWTGSVKETGDCDP 719 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 + ++ AF + ++ H ++ + C ++V EY Sbjct 720 EKGYKPGVQ-------------DEAFEAEVETLGKIRHKNIVKLWCCCSTRDCKLLVYEY 766 Query 690 VEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARL 745 + +G L L +G + + + A LSYL + + +VH ++ NIL+ Sbjct 767 MPNGSLGDLLHSSKGGMLGWQTRFKIILDAAEGLSYLHHDSVPPIVHRDIKSNNILID-- 824 Query 746 GLAEGTSPFIKLSDPGVGLGAL-------SREERVERIPWLAPECLPGGANSLSTAMDKW 798 +++D GV S ++APE ++ D + Sbjct 825 -----GDYGARVADFGVAKAVDLTGKAPKSMSVIAGSCGYIAPEYA--YTLRVNEKSDIY 877 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQ---RQHRLPEPSCPQLAT-----------L 844 FG +LEI + + Q + P+L + + Sbjct 878 SFGVVILEIVTRKRPVDPELGEKDLVKWVCSTLDQKGIEHVIDPKLDSCFKEEISKILNV 937 Query 845 TSQCLTYEPTQRPSFRTILRDLTRL 869 C + P RPS R +++ L + Sbjct 938 GLLCTSPLPINRPSMRRVVKMLQEI 962 >sp|P0C431|HOG1_GIBZE Mitogen-activated protein kinase HOG1 OS=Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) OX=229533 GN=HOG1 PE=3 SV=1 Length=357 Score = 216 bits (549), Expect = 8e-61, Method: Composition-based stats. Identities = 66/283 (23%), Positives = 108/283 (38%), Gaps = 29/283 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VAVK + K P +E+ +L+ L HE++ Sbjct 24 QPVGMGAFGLVC----SARDQLTNQNVAVKKIMKPFSTPVLAKRTYRELKLLKHLKHENV 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L + ER P + L++ + R T + Sbjct 252 SLPKRERQPLRNKFKNADDSAIDLLERMLVFDPKKRITATEAL 294 Score = 129 bits (325), Expect = 4e-31, Method: Composition-based stats. Identities = 36/213 (17%), Positives = 70/213 (33%), Gaps = 18/213 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E D + M + RD+ V +K ++ P +A Y Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAVKKIMKPFSTPVLAKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLKHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + APE + +D W G E+ Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML 208 >sp|Q14680|MELK_HUMAN Maternal embryonic leucine zipper kinase OS=Homo sapiens OX=9606 GN=MELK PE=1 SV=3 Length=651 Score = 224 bits (571), Expect = 8e-61, Method: Composition-based stats. Identities = 72/283 (25%), Positives = 121/283 (43%), Gaps = 26/283 (9%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 +Y + +G G F KV L C + TGEMVA+K + + K Sbjct 1 MKDYDELLKYYELHETIGTGGFAKVKLAC----HILTGEMVAIKIMDKNTLGSDLPRIKT 56 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQ 1005 EI+ L+ L H+HI + E + + +V+EY P G L DY+ + + + + + Sbjct 57 EIEALKNLRHQHICQLYHVLETANK--IFMVLEYCPGGELFDYIISQDRLSEEETRVVFR 114 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 QI +AY+H+Q Y HRDL N+L D +K+ DFGL +Y+ + + Sbjct 115 QIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHL--QTCCGSL 172 Query 1066 FWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 + APE ++ + +DVWS G+ LY L+ V+ L Sbjct 173 AYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDD---------------NVMAL 217 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + RG + P L++ + + R + +NL+ Sbjct 218 YKKIMRG-KYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLN 259 Score = 170 bits (431), Expect = 9e-43, Method: Composition-based stats. Identities = 51/319 (16%), Positives = 103/319 (32%), Gaps = 39/319 (12%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 +G G V + G V +K++D + Sbjct 12 ELHETIGTGGFAKVKLACHILTGEM------------------------VAIKIMDKNTL 47 Query 650 DIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 L + + H H+ ++ V + MV EY G L ++ + Sbjct 48 GSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEE 107 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV-----G 763 ++ V +Q+ SA++Y+ ++ H ++ N+L +KL D G+ G Sbjct 108 ETRV-VFRQIVSAVAYVHSQGYAHRDLKPENLLFDEY-------HKLKLIDFGLCAKPKG 159 Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + + + APE + G + L + D W G L + + Sbjct 160 NKDYHLQTCCGSLAYAAPELIQGKSY-LGSEADVWSMGILLYVLMCGFLPFDDDNVMALY 218 Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 + + ++ +P+ P L Q L +P +R S + +L +Q +N Sbjct 219 KKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNP 278 Query 884 SPASDPTVFHKRYLKKIRD 902 D + + + Sbjct 279 FIHLDDDCVTELSVHHRNN 297 >sp|Q8BW96|KCC1D_MOUSE Calcium/calmodulin-dependent protein kinase type 1D OS=Mus musculus OX=10090 GN=Camk1d PE=1 SV=2 Length=385 Score = 216 bits (551), Expect = 9e-61, Method: Composition-based stats. Identities = 68/269 (25%), Positives = 101/269 (38%), Gaps = 30/269 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG G F +V L TG++ AVK + S + EI +LR + HE+I+ Sbjct 28 TLGTGAFSEVVL----AEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVA 83 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHYI 1020 + E L LVM+ V G L D + +Q+ + + YLH + Sbjct 84 LEDIYESPNH--LYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141 Query 1021 HRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 HRDL N+L D + + I DFGL+K +G V + APE L + Sbjct 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGD----VMSTACGTPGYVAPEVLAQKP 197 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + A D WS GV Y LL + ++L+ P Sbjct 198 YSKAVDCWSIGVIAYILLCGYPPF--------------YDENDSKLFEQILKAEYEFDSP 243 Query 1138 --DKCPCEVYHLMKNCWETEASFRPTFEN 1164 D ++N E + + R T E Sbjct 244 YWDDISDSAKDFIRNLMEKDPNKRYTCEQ 272 Score = 149 bits (376), Expect = 1e-37, Method: Composition-based stats. Identities = 43/314 (14%), Positives = 89/314 (28%), Gaps = 45/314 (14%) Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 + R S + ++ LG G + V Sbjct 1 MARENGESSSSWKKQAEDIKKI----FEFKETLGTGAFSEV------------------- 37 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGP 681 V ++ +K + + +++ ++ H ++ + + Sbjct 38 -----VLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPN 92 Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 +V + V G L + E+G + +Q+ A+ YL +VH ++ N+L Sbjct 93 HLYLVMQLVSGGELFDRI-VEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLL 151 Query 742 LARLGLAEGTSPFIKLSDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKW 798 ++ I +SD G+ ++APE L S A+D W Sbjct 152 ----YYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQ--KPYSKAVDCW 205 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQR-----QHRLPEPSCPQLATLTSQCLTYEP 853 G I G P + S+ + + + +P Sbjct 206 SIGVIAY-ILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264 Query 854 TQRPSFRTILRDLT 867 +R + R Sbjct 265 NKRYTCEQAARHPW 278 >sp|Q9LMN7|WAK5_ARATH Wall-associated receptor kinase 5 OS=Arabidopsis thaliana OX=3702 GN=WAK5 PE=2 SV=1 Length=733 Score = 226 bits (575), Expect = 9e-61, Method: Composition-based stats. Identities = 71/279 (25%), Positives = 115/279 (41%), Gaps = 18/279 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G G V +VA+K + Q + E+ +L + H +++K Sbjct 414 LGQGGQGTVYKGILQ-----DNSIVAIKKARLGDRSQ-VEQFINEVLVLSQINHRNVVKL 467 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQ- 1017 GCC + E L LV E++ G+L D+L S+ L A ++ +AYLH+ Sbjct 468 LGCCLE-TEVPL-LVYEFISSGTLFDHLHGSMFDSSLTWEHRLRIAIEVAGTLAYLHSYA 525 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 IHRD+ N+LLD + K+ DFG ++ +P E G + + PE Sbjct 526 SIPIIHRDVKTANILLDENLTAKVADFGASRLIPMDQEQLTTMVQG--TLGYLDPEYYNT 583 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 SDV+SFGV L ELL+ + P L+ M RL E+++ Sbjct 584 GLLNEKSDVYSFGVVLMELLSGEKALCFERPQSSKHLVSYFVSAMKENRLHEIIDGQVMN 643 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + E + C RP+ + + L+ + Sbjct 644 EYNQREIQESARIAVECTRIMGEERPSMKEVAAELEALR 682 Score = 205 bits (521), Expect = 9e-54, Method: Composition-based stats. Identities = 67/360 (19%), Positives = 128/360 (36%), Gaps = 65/360 (18%) Query 559 SNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616 ++I R + A P +++ + + + LGQG + VY+G L+ Sbjct 376 GGMLIQRLSGAGPSNVDVKIFTEEGMKEATDGYNESRILGQGGQGTVYKGILQDNSI--- 432 Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676 V +K F ++SQ++H ++ + G Sbjct 433 ----------------------VAIKKARLGDRSQVEQFINEVLVLSQINHRNVVKLLGC 470 Query 677 CVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLV 731 C+ ++V E++ G L L + W ++ +A ++A L+YL + ++ Sbjct 471 CLETEVPLLVYEFISSGTLFDHLHGSMFDSSLTWEHRLRIAIEVAGTLAYLHSYASIPII 530 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPG 786 H +V NILL + K++D G +E++ + +L PE Sbjct 531 HRDVKTANILLDE-------NLTAKVADFGASRLIPMDQEQLTTMVQGTLGYLDPEYYNT 583 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY------QRQHRLPEPSCPQ 840 G L+ D + FG L+E+ GE L P +H +++RL E Q Sbjct 584 GL--LNEKSDVYSFGVVLMELLS-GEKALCFERPQSSKHLVSYFVSAMKENRLHEIIDGQ 640 Query 841 L------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASD 888 + A + +C +RPS + + +L L+ + Sbjct 641 VMNEYNQREIQESARIAVECTRIMGEERPSMKEVAAELEALRVKTTKHQWSDQYPKEVEH 700 >sp|C4YRB7|STE20_CANAW Serine/threonine-protein kinase CST20 OS=Candida albicans (strain WO-1) OX=294748 GN=CST20 PE=3 SV=2 Length=1224 Score = 231 bits (590), Expect = 9e-61, Method: Composition-based stats. Identities = 62/266 (23%), Positives = 119/266 (45%), Gaps = 22/266 (8%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G G V L +D + +VA+K + + P+ + EI +++ H +I+ Sbjct 952 KIGQGASGGVFLA-HDVRDKSN--IVAIKQMNLEQQPK-KELIINEILVMKGSSHPNIVN 1007 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 + +G+ L ++MEY+ GSL D + + Q+ + ++ +G+ +LH++ IH Sbjct 1008 FIDSYLLKGD--LWVIMEYMEGGSLTDIVTHSVMTEGQIGVVCRETLKGLKFLHSKGVIH 1065 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RD+ + N+LL+ D +KI DFG + +E R +W APE + ++ Sbjct 1066 RDIKSDNILLNMDGNIKITDFGFCAQI---NEINSKRITMVGTPYWMAPEIVSRKEYGPK 1122 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 DVWS G+ + E+L + T L IA +L P+ Sbjct 1123 VDVWSLGIMIIEML-EGEPPYLNETPLRALYLIATNGTP------------KLKDPESLS 1169 Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167 ++ + C + + + R + L+ Sbjct 1170 YDIRKFLAWCLQVDFNKRADADELLH 1195 Score = 181 bits (458), Expect = 9e-45, Method: Composition-based stats. Identities = 53/296 (18%), Positives = 96/296 (32%), Gaps = 44/296 (15%) Query 585 DQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 D E+ L +GQG V+ R + V +K Sbjct 942 DPNELYVDLVKIGQGASGGVFLAH-----------------------DVRDKSNIVAIKQ 978 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 ++ +M SH ++ + + ++ EY+E G L + Sbjct 979 MNLEQQPKKELIINEILVMKGSSHPNIVNFIDSYLLKGDLWVIMEYMEGGSLTDIVTHS- 1037 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + VV ++ L +L +K ++H ++ NILL IK++D G Sbjct 1038 -VMTEGQIGVVCRETLKGLKFLHSKGVIHRDIKSDNILLN-------MDGNIKITDFGFC 1089 Query 764 LGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 R V W+APE + +D W G ++E+ +GE P + + Sbjct 1090 AQINEINSKRITMVGTPYWMAPEIVS--RKEYGPKVDVWSLGIMIIEML-EGEPPYLNET 1146 Query 820 PSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P + PE + + CL + +R +L D + Sbjct 1147 PLRALYLIATNGTPKLKDPESLSYDIRKFLAWCLQVDFNKRADADELLHDNFITEC 1202 >sp|Q69SP5|EREC1_ORYSJ LRR receptor-like serine/threonine-protein kinase ER1 OS=Oryza sativa subsp. japonica OX=39947 GN=ER1 PE=1 SV=1 Length=978 Score = 229 bits (585), Expect = 9e-61, Method: Composition-based stats. Identities = 73/336 (22%), Positives = 128/336 (38%), Gaps = 23/336 (7%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 L P P F+ + +L +N + + L + + Sbjct 592 LMILVAVCRPHSPPVFKDVSVSKPVSNVPPKLVILHMNLSLLVYEDIMTMTENLSEKYII 651 Query 904 GEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963 G G V + VAVK L A PQ ++ E++ + ++ H +++ + Sbjct 652 GYGASSTVYKCVSKNR-----KPVAVKKLYAHY-PQSFKEFETELETVGSIKHRNLVSLQ 705 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMAYLH--- 1015 G L +Y+ GSL D L + + L A +G+AYLH Sbjct 706 GYSLSPVGN--LLFYDYMENGSLWDVLHEGPTKKKKLDWETRLRIALGAAQGLAYLHHDC 763 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + IHRD+ ++N+LLD D + DFG+AK++ + + + PE + Sbjct 764 SPRIIHRDVKSKNILLDKDYEAHLTDFGIAKSLCVSKTH--TSTYVMGTIGYIDPEYART 821 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + SDV+S+G+ L ELLT P L + + + E ++ Sbjct 822 SRLNEKSDVYSYGIVLLELLTGK----KPVDNECNLHHLILSKTANNAVMETVDPDIADT 877 Query 1136 RPD-KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 D +V+ L C + + S RPT ++ +L Sbjct 878 CKDLGEVKKVFQLALLCTKRQPSDRPTMHEVVRVLD 913 Score = 189 bits (481), Expect = 7e-48, Method: Composition-based stats. Identities = 63/378 (17%), Positives = 124/378 (33%), Gaps = 66/378 (17%) Query 543 DCFSLRRCCLPQ-PGETSNLIIMRGARASPRTL-----NLSQLSFHRVDQ--KEITQLSH 594 L C P P ++ + + P L NLS L + + + +++ Sbjct 591 LLMILVAVCRPHSPPVFKDVSVSKPVSNVPPKLVILHMNLSLLVYEDIMTMTENLSEKYI 650 Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 +G G + VY+ + V +K L + Sbjct 651 IGYGASSTVYKCVSKNRKP-------------------------VAVKKLYAHYPQSFKE 685 Query 655 FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR---ERGHVPMAWK 711 F + + H +L + G + N++ +Y+E+G L L ++ + + Sbjct 686 FETELETVGSIKHRNLVSLQGYSLSPVGNLLFYDYMENGSLWDVLHEGPTKKKKLDWETR 745 Query 712 MVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG--- 765 + +A A L+YL + ++H +V +NILL + A L+D G+ Sbjct 746 LRIALGAAQGLAYLHHDCSPRIIHRDVKSKNILLDKDYEAH-------LTDFGIAKSLCV 798 Query 766 --ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + + I ++ PE + L+ D + +G LLE+ + + Sbjct 799 SKTHTSTYVMGTIGYIDPEYART--SRLNEKSDVYSYGIVLLELLTGKKPVDNECNLHHL 856 Query 824 EHFYQRQHRLPEPSCPQLAT-------------LTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + + E P +A L C +P+ RP+ ++R L L Sbjct 857 ILSKTANNAVMETVDPDIADTCKDLGEVKKVFQLALLCTKRQPSDRPTMHEVVRVLDCLV 916 Query 871 PHNLADVLTVNPDSPASD 888 + P Sbjct 917 RPDPPPKSAQQLAMPQRP 934 >sp|P0CY24|STE20_CANAL Serine/threonine-protein kinase CST20 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=CST20 PE=3 SV=1 Length=1228 Score = 231 bits (590), Expect = 9e-61, Method: Composition-based stats. Identities = 62/266 (23%), Positives = 119/266 (45%), Gaps = 22/266 (8%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G G V L +D + +VA+K + + P+ + EI +++ H +I+ Sbjct 956 KIGQGASGGVFLA-HDVRDKSN--IVAIKQMNLEQQPK-KELIINEILVMKGSSHPNIVN 1011 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 + +G+ L ++MEY+ GSL D + + Q+ + ++ +G+ +LH++ IH Sbjct 1012 FIDSYLLKGD--LWVIMEYMEGGSLTDIVTHSVMTEGQIGVVCRETLKGLKFLHSKGVIH 1069 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RD+ + N+LL+ D +KI DFG + +E R +W APE + ++ Sbjct 1070 RDIKSDNILLNMDGNIKITDFGFCAQI---NEINSKRITMVGTPYWMAPEIVSRKEYGPK 1126 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 DVWS G+ + E+L + T L IA +L P+ Sbjct 1127 VDVWSLGIMIIEML-EGEPPYLNETPLRALYLIATNGTP------------KLKDPESLS 1173 Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167 ++ + C + + + R + L+ Sbjct 1174 YDIRKFLAWCLQVDFNKRADADELLH 1199 Score = 181 bits (458), Expect = 9e-45, Method: Composition-based stats. Identities = 53/296 (18%), Positives = 96/296 (32%), Gaps = 44/296 (15%) Query 585 DQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 D E+ L +GQG V+ R + V +K Sbjct 946 DPNELYVDLVKIGQGASGGVFLAH-----------------------DVRDKSNIVAIKQ 982 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 ++ +M SH ++ + + ++ EY+E G L + Sbjct 983 MNLEQQPKKELIINEILVMKGSSHPNIVNFIDSYLLKGDLWVIMEYMEGGSLTDIVTHS- 1041 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + VV ++ L +L +K ++H ++ NILL IK++D G Sbjct 1042 -VMTEGQIGVVCRETLKGLKFLHSKGVIHRDIKSDNILLN-------MDGNIKITDFGFC 1093 Query 764 LGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 R V W+APE + +D W G ++E+ +GE P + + Sbjct 1094 AQINEINSKRITMVGTPYWMAPEIVS--RKEYGPKVDVWSLGIMIIEML-EGEPPYLNET 1150 Query 820 PSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P + PE + + CL + +R +L D + Sbjct 1151 PLRALYLIATNGTPKLKDPESLSYDIRKFLAWCLQVDFNKRADADELLHDNFITEC 1206 >sp|P0CY23|STE20_CANAX Serine/threonine-protein kinase CST20 OS=Candida albicans OX=5476 GN=CST20 PE=3 SV=1 Length=1230 Score = 231 bits (590), Expect = 9e-61, Method: Composition-based stats. Identities = 62/266 (23%), Positives = 119/266 (45%), Gaps = 22/266 (8%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G G V L +D + +VA+K + + P+ + EI +++ H +I+ Sbjct 958 KIGQGASGGVFLA-HDVRDKSN--IVAIKQMNLEQQPK-KELIINEILVMKGSSHPNIVN 1013 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 + +G+ L ++MEY+ GSL D + + Q+ + ++ +G+ +LH++ IH Sbjct 1014 FIDSYLLKGD--LWVIMEYMEGGSLTDIVTHSVMTEGQIGVVCRETLKGLKFLHSKGVIH 1071 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RD+ + N+LL+ D +KI DFG + +E R +W APE + ++ Sbjct 1072 RDIKSDNILLNMDGNIKITDFGFCAQI---NEINSKRITMVGTPYWMAPEIVSRKEYGPK 1128 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 DVWS G+ + E+L + T L IA +L P+ Sbjct 1129 VDVWSLGIMIIEML-EGEPPYLNETPLRALYLIATNGTP------------KLKDPESLS 1175 Query 1142 CEVYHLMKNCWETEASFRPTFENLIP 1167 ++ + C + + + R + L+ Sbjct 1176 YDIRKFLAWCLQVDFNKRADADELLH 1201 Score = 181 bits (458), Expect = 9e-45, Method: Composition-based stats. Identities = 53/296 (18%), Positives = 96/296 (32%), Gaps = 44/296 (15%) Query 585 DQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 D E+ L +GQG V+ R + V +K Sbjct 948 DPNELYVDLVKIGQGASGGVFLAH-----------------------DVRDKSNIVAIKQ 984 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 ++ +M SH ++ + + ++ EY+E G L + Sbjct 985 MNLEQQPKKELIINEILVMKGSSHPNIVNFIDSYLLKGDLWVIMEYMEGGSLTDIVTHS- 1043 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + VV ++ L +L +K ++H ++ NILL IK++D G Sbjct 1044 -VMTEGQIGVVCRETLKGLKFLHSKGVIHRDIKSDNILLN-------MDGNIKITDFGFC 1095 Query 764 LGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 R V W+APE + +D W G ++E+ +GE P + + Sbjct 1096 AQINEINSKRITMVGTPYWMAPEIVS--RKEYGPKVDVWSLGIMIIEML-EGEPPYLNET 1152 Query 820 PSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P + PE + + CL + +R +L D + Sbjct 1153 PLRALYLIATNGTPKLKDPESLSYDIRKFLAWCLQVDFNKRADADELLHDNFITEC 1208 >sp|Q00532|CDKL1_HUMAN Cyclin-dependent kinase-like 1 OS=Homo sapiens OX=9606 GN=CDKL1 PE=1 SV=8 Length=357 Score = 215 bits (548), Expect = 9e-61, Method: Composition-based stats. Identities = 67/293 (23%), Positives = 125/293 (43%), Gaps = 29/293 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960 +GEG +G V + N TG++VA+K L+++ P + +EI +L+ L H +++ Sbjct 9 KIGEGSYGVV----FKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLV 64 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + + L LV EY L + + + + Q + + + H + Sbjct 65 NLLEVFRRK--RRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNC 122 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEYKF 1078 IHRD+ N+L+ ++K+ DFG A+ + +YY D + ++ +PE L + ++ Sbjct 123 IHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYY---TDYVATRWYRSPELLVGDTQY 179 Query 1079 YYASDVWSFGVTLYELLTHCD-----SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 DVW+ G ELL+ S + +G + + T G + Sbjct 180 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVK 239 Query 1134 LPRPDKC-PCEVY---------HLMKNCWETEASFRPTFENLI--PILKTVHE 1174 +P P+ P E+ L+K C + + R T E L+ P + + E Sbjct 240 IPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIRE 292 Score = 154 bits (388), Expect = 2e-39, Method: Composition-based stats. Identities = 50/250 (20%), Positives = 87/250 (35%), Gaps = 40/250 (16%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ ++ +G+G+ V++ R R G V +K Sbjct 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQ------------------------IVAIKKFL 36 Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 S D I ++ Q+ H +L + V R +V EY +H L R +R Sbjct 37 ESEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQR 96 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 G VP + Q A+++ N +H +V NIL+ + IKL D G Sbjct 97 G-VPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENILITK-------HSVIKLCDFGFA 148 Query 764 LGAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + V + +PE L G +D W G E+ G +S Sbjct 149 RLLTGPSDYYTDYVATRWYRSPELLV-GDTQYGPPVDVWAIGCVFAELLS-GVPLWPGKS 206 Query 820 PSEKEHFYQR 829 ++ + ++ Sbjct 207 DVDQLYLIRK 216 >sp|Q6R2K1|SRF5_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 5 OS=Arabidopsis thaliana OX=3702 GN=SRF5 PE=1 SV=1 Length=699 Score = 225 bits (573), Expect = 9e-61, Method: Composition-based stats. Identities = 70/284 (25%), Positives = 117/284 (41%), Gaps = 26/284 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI-LRTLYHEHIIK 961 LGEG G+V Y G +AVK + + +S I + L + H++I + Sbjct 410 LGEGSIGRVYRAKY-----SDGRTLAVKKIDSTLFDSGKSEGITPIVMSLSKIRHQNIAE 464 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMAYLH- 1015 G C +QG LV EY GSL ++L + + A + YLH Sbjct 465 LVGYCSEQGHN--MLVYEYFRNGSLHEFLHLSDCFSKPLTWNTRVRIALGTARAVEYLHE 522 Query 1016 --AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + +H+++ + N+LLD D ++ D+GL+K +R + + APE Sbjct 523 ACSPSVMHKNIKSSNILLDADLNPRLSDYGLSKFY--------LRTSQNLGEGYNAPEAR 574 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQM-TVLRLTELLERG 1131 + SDV+SFGV + ELLT P L+ A Q+ + L+ + + Sbjct 575 DPSAYTPKSDVYSFGVVMLELLTGRVPFDGEKPRPERSLVRWATPQLHDIDALSNIADPA 634 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 P K ++ C + E FRP ++ L + ++ Sbjct 635 LHGLYPPKSLSRFADIIALCVQVEPEFRPPMSEVVEALVRMVQR 678 Score = 177 bits (449), Expect = 9e-45, Method: Composition-based stats. Identities = 61/334 (18%), Positives = 115/334 (34%), Gaps = 63/334 (19%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 S R+ +LS + + + LG+G+ VY + + Sbjct 384 TSTRSAVEFELSDLQSATANFSPGNLLGEGSIGRVYRAKYSDGRTL-------------- 429 Query 629 PGRDRGQELRVVLKVLDPSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 +K +D + D + +S++ H ++A + G C N++V Sbjct 430 -----------AVKKIDSTLFDSGKSEGITPIVMSLSKIRHQNIAELVGYCSEQGHNMLV 478 Query 687 TEYVEHGPLDVWLRRER---GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNI 740 EY +G L +L + ++ +A A A+ YL + +++H N+ NI Sbjct 479 YEYFRNGSLHEFLHLSDCFSKPLTWNTRVRIALGTARAVEYLHEACSPSVMHKNIKSSNI 538 Query 741 LLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800 LL +LSD G+ L + + + APE ++ + D + F Sbjct 539 LLD-------ADLNPRLSDYGLSKFYLRTSQNLGE-GYNAPEA--RDPSAYTPKSDVYSF 588 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQR-------------------QHRLPEPSCPQL 841 G +LE+ G P P + + P S + Sbjct 589 GVVMLELL-TGRVPFDGEKPRPERSLVRWATPQLHDIDALSNIADPALHGLYPPKSLSRF 647 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 A + + C+ EP RP ++ L R+ + Sbjct 648 ADIIALCVQVEPEFRPPMSEVVEALVRMVQRSSM 681 >sp|Q09892|HOG1_SCHPO Mitogen-activated protein kinase sty1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=sty1 PE=1 SV=1 Length=349 Score = 215 bits (548), Expect = 9e-61, Method: Composition-based stats. Identities = 65/306 (21%), Positives = 115/306 (38%), Gaps = 29/306 (9%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADC 936 + + ++ +G G FG V + TG VAVK + K Sbjct 1 MAEFIRTQIFGTCFEITTRYSDLQPIGMGAFGLVC----SAKDQLTGMNVAVKKIMKPFS 56 Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG 996 P +E+ +L+ L HE+II E + V E + L L + Sbjct 57 TPVLAKRTYRELKLLKHLRHENIISLSDIFISPFED-IYFVTELL-GTDLHRLLTSRPLE 114 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 + F QI G+ ++H+ IHRDL N+L++ + +KI DFGLA+ Y Sbjct 115 TQFIQYFLYQILRGLKFVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY- 173 Query 1057 VREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLE 1110 S ++ APE + K+ D+WS G E++ + + E Sbjct 174 -----VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGRDHVNQFSIITE 228 Query 1111 LIGIAQGQM-------TVLRLTELLERGERLPRPD---KCPCEVYHLMKNCWETEASFRP 1160 L+G ++ LR + L + E++P + + L++ + R Sbjct 229 LLGTPPMEVIETICSKNTLRFVQSLPQKEKVPFAEKFKNADPDAIDLLEKMLVFDPRKRI 288 Query 1161 TFENLI 1166 + + + Sbjct 289 SAADAL 294 Score = 134 bits (336), Expect = 1e-32, Method: Composition-based stats. Identities = 35/231 (15%), Positives = 77/231 (33%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E D + M + +D+ + V +K ++ P +A Y Sbjct 10 FGTCFE---ITTRYSDLQPIGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPFEDIYFVTELL-GTDLHRLLTSR--PLETQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L ++ + ++H ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKFVHSAGVIHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + + +D W G E+ +G+ R + Sbjct 177 RYYRAPE-IMLTWQKYNVEVDIWSAGCIFAEMI-EGKPLFPGRDHVNQFSI 225 >sp|P34117|CDK5_DICDI Cyclin-dependent kinase 5 homolog OS=Dictyostelium discoideum OX=44689 GN=cdk5 PE=2 SV=2 Length=292 Score = 213 bits (542), Expect = 9e-61, Method: Composition-based stats. Identities = 72/288 (25%), Positives = 120/288 (42%), Gaps = 29/288 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-GWKQEIDILR 952 KI LGEG +G V Y N TGE+VA+K ++ D + +EI +L+ Sbjct 1 MEKYSKIEKLGEGTYGIV----YKAKNRETGEIVALKRIRLDSEDEGVPCTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEG 1010 L H +I++ E+ L LV EY+ L+ YL I + F Q+ +G Sbjct 57 ELKHPNIVRLHDVI--HTERKLTLVFEYLDQ-DLKKYLDECGGEISKPTIKSFMYQLLKG 113 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 +A+ H +HRDL +N+L++ +K+ DFGLA+A Y +++ AP Sbjct 114 VAFCHDHRVLHRDLKPQNLLINRKGELKLADFGLARAFGIPVRTYSHE---VVTLWYRAP 170 Query 1071 ECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTVLRL 1124 + L K+ D+WS G E+ + + +++G + + + Sbjct 171 DVLMGSRKYSTPIDIWSAGCIFAEMASGRPLFPGSGTSDQLFRIFKILGTPNEE-SWPSI 229 Query 1125 TELLERGERLPR-PDKCPCEVYH--------LMKNCWETEASFRPTFE 1163 TEL E P P + H L+ + + + R T Sbjct 230 TELPEYKTDFPVHPAHQLSSIVHGLDEKGLNLLSKMLQYDPNQRITAA 277 Score = 167 bits (423), Expect = 8e-45, Method: Composition-based stats. Identities = 51/265 (19%), Positives = 98/265 (37%), Gaps = 39/265 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-- 643 ++ +++ LG+GT VY+ + R G V LK Sbjct 1 MEKYSKIEKLGEGTYGIVYKAKNRETGE------------------------IVALKRIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 LD + SL+ ++ H ++ +H V + +V EY++ L +L Sbjct 37 LDSEDEGVPCTAIREISLLKELKHPNIVRLHDVIHTERKLTLVFEYLDQ-DLKKYLDECG 95 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 G + QL +++ + ++H ++ +N+L+ R G +KL+D G+ Sbjct 96 GEISKPTIKSFMYQLLKGVAFCHDHRVLHRDLKPQNLLINRKGE-------LKLADFGLA 148 Query 764 LG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + V + + AP+ L G+ ST +D W G E+ S + Sbjct 149 RAFGIPVRTYSHEVVTLWYRAPDVLM-GSRKYSTPIDIWSAGCIFAEMASGRPLFPGSGT 207 Query 820 PSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ E S P + L Sbjct 208 SDQLFRIFKILGTPNEESWPSITEL 232 >sp|Q1KTF2|HOG1_ZYMTI Mitogen-activated protein kinase Hog1 OS=Zymoseptoria tritici (strain CBS 115943 / IPO323) OX=336722 GN=Hog1 PE=3 SV=2 Length=357 Score = 215 bits (548), Expect = 1e-60, Method: Composition-based stats. Identities = 65/276 (24%), Positives = 108/276 (39%), Gaps = 29/276 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + TG+ VAVK + K P +E+ +L+ L HE++ Sbjct 24 QPVGMGAFGLVC----SAKDQLTGQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLKHENV 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 D+WS G E+L + + +L+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITDLLGTPPDDVISTICSENTLRFVQ 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFR 1159 L + ER P + + L++ + R Sbjct 252 SLPKRERQPLKNKFKNADPQAIELLERMLVFDPRKR 287 Score = 133 bits (334), Expect = 2e-32, Method: Composition-based stats. Identities = 35/234 (15%), Positives = 74/234 (32%), Gaps = 19/234 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + +D+ V +K ++ P ++ Y Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSAKDQLTGQAVAVKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLKHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 + APE + +D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSIITD 228 >sp|C0LGH2|Y1561_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g56130 OS=Arabidopsis thaliana OX=3702 GN=At1g56130 PE=2 SV=2 Length=1032 Score = 230 bits (586), Expect = 1e-60, Method: Composition-based stats. Identities = 78/317 (25%), Positives = 127/317 (40%), Gaps = 18/317 (6%) Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920 TI + R + V P + LGEG FG V N Sbjct 658 TIRKRRKRYTDDEELLGMDVKPYIFTYSELKSATQDFDPSNKLGEGGFGPVYKG-----N 712 Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 G +VAVK L Q + + EI + ++ H +++K GCC + + LV EY Sbjct 713 LNDGRVVAVKLLSVG-SRQGKGQFVAEIVAISSVLHRNLVKLYGCCFEGEHR--MLVYEY 769 Query 981 VPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDND 1034 +P GSL L + + + G+ YLH + +HRD+ A N+LLD+ Sbjct 770 LPNGSLDQALFGDKTLHLDWSTRYEICLGVARGLVYLHEEASVRIVHRDVKASNILLDSR 829 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 + +I DFGLAK + + R G + + APE +DV++FGV EL Sbjct 830 LVPQISDFGLAKLYDDKKTHISTRVAG--TIGYLAPEYAMRGHLTEKTDVYAFGVVALEL 887 Query 1095 LTHCDSSQSPPTKFLE-LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 ++ +S + + L+ A R EL++ + + + C + Sbjct 888 VSGRPNSDENLEEEKKYLLEWAWNLHEKSRDIELIDDKLT-DFNMEEAKRMIGIALLCTQ 946 Query 1154 TEASFRPTFENLIPILK 1170 T + RP ++ +L Sbjct 947 TSHALRPPMSRVVAMLS 963 Score = 220 bits (560), Expect = 2e-57, Method: Composition-based stats. Identities = 68/328 (21%), Positives = 122/328 (37%), Gaps = 52/328 (16%) Query 517 EGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL 576 +G R+ ++ + + + AG F++R+ + + L+ G P Sbjct 630 KGKNRT-GTIVGVIVGVGLLSILAGVVMFTIRKR-RKRYTDDEELL---GMDVKPYIFTY 684 Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 S+L + ++ + LG+G VY+G L Sbjct 685 SEL---KSATQDFDPSNKLGEGGFGPVYKGNLNDGR------------------------ 717 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K+L F +S V H +L ++G C G ++V EY+ +G LD Sbjct 718 -VVAVKLLSVGSRQGKGQFVAEIVAISSVLHRNLVKLYGCCFEGEHRMLVYEYLPNGSLD 776 Query 697 VWLRRERG-HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTS 752 L ++ H+ + + + +A L YL + +VH +V NILL + + Sbjct 777 QALFGDKTLHLDWSTRYEICLGVARGLVYLHEEASVRIVHRDVKASNILLDSRLVPQ--- 833 Query 753 PFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +SD G+ ++ + I +LAPE G L+ D + FG LE+ Sbjct 834 ----ISDFGLAKLYDDKKTHISTRVAGTIGYLAPEYAMRG--HLTEKTDVYAFGVVALEL 887 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 G EK++ + L E Sbjct 888 VS-GRPNSDENLEEEKKYLLEWAWNLHE 914 >sp|P54645|AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Rattus norvegicus OX=10116 GN=Prkaa1 PE=1 SV=2 Length=559 Score = 221 bits (564), Expect = 1e-60, Method: Composition-based stats. Identities = 77/274 (28%), Positives = 111/274 (41%), Gaps = 30/274 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953 + LG G FGKV + ++ TG VAVK L ++EI L+ Sbjct 26 HYILGDTLGVGTFGKVKVG----KHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKL 81 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012 H HIIK + + +VMEYV G L DY+ ++ + + QQI G+ Sbjct 82 FRHPHIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVD 139 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE Sbjct 140 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 195 Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + D+WS GV LY LL V L + + G Sbjct 196 ISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDH---------------VPTLFKKICDG 240 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P V L+K+ + + R T +++ Sbjct 241 IFYT-PQYLNPSVISLLKHMLQVDPMKRATIKDI 273 Score = 182 bits (463), Expect = 2e-47, Method: Composition-based stats. Identities = 54/298 (18%), Positives = 94/298 (32%), Gaps = 39/298 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 Q RV LG GT V G+ + G Sbjct 15 KQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGH----------------------- 51 Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +V +K+L+ D+ + H H+ ++ V + MV EYV G Sbjct 52 -KVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGG 110 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L ++ + G + + QQ+ S + Y +VH ++ N+LL Sbjct 111 ELFDYICKN-GRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD-------AHM 162 Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ E + APE + G + +D W G L + Sbjct 163 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSSGVILYALLCG 221 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 P+ + P+ P + +L L +P +R + + I Sbjct 222 TLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWF 279 >sp|Q968Y9|INSR_CAEEL Insulin-like receptor OS=Caenorhabditis elegans OX=6239 GN=daf-2 PE=1 SV=2 Length=1846 Score = 232 bits (592), Expect = 1e-60, Method: Composition-based stats. Identities = 94/319 (29%), Positives = 137/319 (43%), Gaps = 34/319 (11%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV- 927 L + + +D + + + GEG FGKV L + G+ Sbjct 1218 LSDFMQLNPEYCVDNKYNADDWELRQDDVVLGQQCGEGSFGKVYLGTGNNVVSLMGDRFG 1277 Query 928 --AVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGS 985 A+K D + E +I++ I+K G + +VME + LG+ Sbjct 1278 PCAIKINVDDPASTENLNYLMEANIMKNFKTNFIVKLYGVIS--TVQPAMVVMEMMDLGN 1335 Query 986 LRDYLPRHSIGL---------------AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030 LRDYL + +A QIC+GMAYL + + HRDLAARN + Sbjct 1336 LRDYLRSKREDEVFNETDCNFFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCM 1395 Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 ++ D VKIGDFG+A+ + H+YY+ PV W +PE LK+ KF SDVWSFGV Sbjct 1396 INRDETVKIGDFGMARDLFY-HDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVV 1454 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 LYE++T + L I + + + P+ C Y +MK Sbjct 1455 LYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKK-------------PECCENYWYKVMKM 1501 Query 1151 CWETEASFRPTFENLIPIL 1169 CW RPTF L+ +L Sbjct 1502 CWRYSPRDRPTFLQLVHLL 1520 Score = 210 bits (534), Expect = 1e-53, Method: Composition-based stats. Identities = 60/307 (20%), Positives = 110/307 (36%), Gaps = 47/307 (15%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 + Q ++ G+G+ VY G + + DR + Sbjct 1237 DDWELRQDDVVLGQQCGEGSFGKVYLGT---------------GNNVVSLMGDRFGPCAI 1281 Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 + V DP+ + L + A++M + ++GV ++V E ++ G L +L Sbjct 1282 KINVDDPASTEN-LNYLMEANIMKNFKTNFIVKLYGVISTVQPAMVVMEMMDLGNLRDYL 1340 Query 700 RRERGH-------------VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 R +R +P A Q+ ++YLE+ H ++ RN ++ R Sbjct 1341 RSKREDEVFNETDCNFFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINR-- 1398 Query 747 LAEGTSPFIKLSDPGVGLGALSREE------RVERIPWLAPECLPGGANSLSTAMDKWGF 800 +K+ D G+ + R+ + W++PE L G + D W F Sbjct 1399 -----DETVKIGDFGMARDLFYHDYYKPSGKRMMPVRWMSPESLKDG--KFDSKSDVWSF 1451 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL---PEPSCPQLATLTSQCLTYEPTQRP 857 G L E+ G P S E ++ ++ PE + C Y P RP Sbjct 1452 GVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRDRP 1511 Query 858 SFRTILR 864 +F ++ Sbjct 1512 TFLQLVH 1518 >sp|G5EFM9|NEKL3_CAEEL Serine/threonine-protein kinase nekl-3 OS=Caenorhabditis elegans OX=6239 GN=nekl-3 PE=1 SV=1 Length=302 Score = 213 bits (543), Expect = 1e-60, Method: Composition-based stats. Identities = 60/288 (21%), Positives = 117/288 (41%), Gaps = 30/288 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHI 959 +G+G F +V + VA+K ++ + R +EID+L+ L H ++ Sbjct 28 KIGKGQFSEV----FRAQCTWVDLHVALKKIQVFEMVDQKARQDCLKEIDLLKQLNHVNV 83 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYL 1014 I+Y D + L +V+E G + + I + + Q+ +A++ Sbjct 84 IRYYASFIDNNQ--LNIVLELAEAGDMSRMIKHFKKGGRLIPEKTIWKYFVQLARALAHM 141 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H++ +HRD+ NV + + +VK+GD GL + ++ +PE ++ Sbjct 142 HSKRIMHRDIKPANVFITGNGIVKLGDLGLGRFFS---SKTTAAHSLVGTPYYMSPERIQ 198 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 E + + SD+WS G LYE+ +M + L + +E E Sbjct 199 ESGYNFKSDLWSTGCLLYEMAALQSPFYG-------------DKMNLYSLCKKIENCEYP 245 Query 1135 PRPDKC-PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 P P ++ L+ C EAS RP ++ + + ++ + Sbjct 246 PLPADIYSTQLRDLVSRCILPEASKRPETSEVLQVAEHMNNYFSPSGD 293 Score = 161 bits (408), Expect = 1e-42, Method: Composition-based stats. Identities = 48/320 (15%), Positives = 105/320 (33%), Gaps = 47/320 (15%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 ++ + +G+G + V+ + +L V L Sbjct 16 DKLSLELFIIEKKIGKGQFSEVFRAQCTWV------------------------DLHVAL 51 Query 642 KVLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 K + + L+ Q++H ++ + + + +V E E G + Sbjct 52 KKIQVFEMVDQKARQDCLKEIDLLKQLNHVNVIRYYASFIDNNQLNIVLELAEAGDMSRM 111 Query 699 LRRERGH---VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 ++ + +P QLA AL+++ +K ++H ++ N+ + + + Sbjct 112 IKHFKKGGRLIPEKTIWKYFVQLARALAHMHSKRIMHRDIKPANVFIT-------GNGIV 164 Query 756 KLSDPGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 KL D G+G S+ V +++PE + + D W G L E+ Sbjct 165 KLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIQESGYNF--KSDLWSTGCLLYEMAALQ 222 Query 812 EAPLQSRSPS----EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + +K + + QL L S+C+ E ++RP +L+ Sbjct 223 SPFYGDKMNLYSLCKKIENCEYPPLPADIYSTQLRDLVSRCILPEASKRPETSEVLQVAE 282 Query 868 RLQPHNLADVLTVNPDSPAS 887 + + S Sbjct 283 HMNNYFSPSGDQSTTPSTQF 302 >sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapiens OX=9606 GN=LIMK2 PE=1 SV=1 Length=638 Score = 224 bits (570), Expect = 1e-60, Method: Composition-based stats. Identities = 78/309 (25%), Positives = 131/309 (42%), Gaps = 38/309 (12%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 S + +F L LG+G FG+ T+ TG+++ +K L C + + Sbjct 316 RCSSSYSQQIFRPCDLIHGEVLGKGFFGQ----AIKVTHKATGKVMVMKEL-IRCDEETQ 370 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQL 1000 + E+ ++R+L H +++K+ G +K L L+ EY+ G+L+D+L Q Sbjct 371 KTFLTEVKVMRSLDHPNVLKFIGVLYK--DKKLNLLTEYIEGGTLKDFLRSMDPFPWQQK 428 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY----- 1055 + FA+ I GMAYLH+ IHRDL + N L+ D+ V + DFGL++ + E + Sbjct 429 VRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRAPMEKA 488 Query 1056 ------------RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 + R +W APE L + D++SFG+ L E++ + Sbjct 489 TTKKRTLRKNDRKKRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPD 548 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163 + L+ G L + + P CP + L C E RP F Sbjct 549 CLPRTLDF-----GLNVKLFWEKFV--------PTDCPPAFFPLAAICCRLEPESRPAFS 595 Query 1164 NLIPILKTV 1172 L + + Sbjct 596 KLEDSFEAL 604 Score = 200 bits (509), Expect = 8e-53, Method: Composition-based stats. Identities = 63/345 (18%), Positives = 111/345 (32%), Gaps = 62/345 (18%) Query 553 PQPGETSNLIIMRGARASPRTLN-LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 P P ++ + +L S S ++ LG+G + + Sbjct 294 PGPSSPKEPLLFSRDISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKAT 353 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 G +V+K L + F +M + H ++ Sbjct 354 GK------------------------VMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVL 389 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 GV + + ++TEY+E G L +LR P K+ A+ +AS ++YL + ++ Sbjct 390 KFIGVLYKDKKLNLLTEYIEGGTLKDFLR-SMDPFPWQQKVRFAKGIASGMAYLHSMCII 448 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------------------------GAL 767 H ++ N L+ + ++D G+ Sbjct 449 HRDLNSHNCLI-------KLDKTVVVADFGLSRLIVEERKRAPMEKATTKKRTLRKNDRK 501 Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--FDGEAPLQSRSPSEKEH 825 R V W+APE L G S +D + FG L EI + R+ + Sbjct 502 KRYTVVGNPYWMAPEMLNG--KSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLN 559 Query 826 FY-QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + +P P L + C EP RP+F + L Sbjct 560 VKLFWEKFVPTDCPPAFFPLAAICCRLEPESRPAFSKLEDSFEAL 604 >sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4 Length=559 Score = 221 bits (564), Expect = 1e-60, Method: Composition-based stats. Identities = 77/274 (28%), Positives = 111/274 (41%), Gaps = 30/274 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953 + LG G FGKV + ++ TG VAVK L ++EI L+ Sbjct 26 HYILGDTLGVGTFGKVKVG----KHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKL 81 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012 H HIIK + + +VMEYV G L DY+ ++ + + QQI G+ Sbjct 82 FRHPHIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVD 139 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE Sbjct 140 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 195 Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + D+WS GV LY LL V L + + G Sbjct 196 ISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDH---------------VPTLFKKICDG 240 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P V L+K+ + + R T +++ Sbjct 241 IFYT-PQYLNPSVISLLKHMLQVDPMKRATIKDI 273 Score = 182 bits (463), Expect = 2e-47, Method: Composition-based stats. Identities = 54/298 (18%), Positives = 94/298 (32%), Gaps = 39/298 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 Q RV LG GT V G+ + G Sbjct 15 KQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGH----------------------- 51 Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +V +K+L+ D+ + H H+ ++ V + MV EYV G Sbjct 52 -KVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGG 110 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L ++ + G + + QQ+ S + Y +VH ++ N+LL Sbjct 111 ELFDYICKN-GRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD-------AHM 162 Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ E + APE + G + +D W G L + Sbjct 163 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSSGVILYALLCG 221 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 P+ + P+ P + +L L +P +R + + I Sbjct 222 TLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWF 279 >sp|O88866|HUNK_MOUSE Hormonally up-regulated neu tumor-associated kinase OS=Mus musculus OX=10090 GN=Hunk PE=2 SV=1 Length=714 Score = 225 bits (574), Expect = 1e-60, Method: Composition-based stats. Identities = 75/301 (25%), Positives = 122/301 (41%), Gaps = 25/301 (8%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--- 941 YL R LGEG F KV + + TGE VA+K + + Sbjct 50 RDFQHHKRVGNYLIGSRKLGEGSFAKVR----EGLHVLTGEKVAIKVIDKKRAKKDTYVT 105 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQL 1000 ++E I + + H +I + E E S LVME P G+L + + + A+ Sbjct 106 KNLRREGQIQQMIRHPNITQLLDILE--TENSYYLVMELCPGGNLMHKIYEKKRLDEAEA 163 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 + +Q+ + +LH +HRDL N+LLD D +K+ DFGL+ Sbjct 164 RRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQ 223 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 SP + APE L K+ DVWS GV +Y +LT P L Sbjct 224 CGSPA-YAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALY-------- 274 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180 +++++ P P + + +++ E + RP + + + ++E Y G+ Sbjct 275 ----QKMVDKAMN-PLPTQLSTGAVNFLRSLLEPDPVKRPNIQQALAN-RWLNENYTGKV 328 Query 1181 P 1181 P Sbjct 329 P 329 Score = 164 bits (414), Expect = 2e-40, Method: Composition-based stats. Identities = 59/344 (17%), Positives = 105/344 (31%), Gaps = 49/344 (14%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L H+ + LG+G+ V EG + G Sbjct 49 LRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGE---------------------- 86 Query 636 ELRVVLKVLDPSHHD----IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +V +KV+D + + + H ++ + + +V E Sbjct 87 --KVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCP 144 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G L + E+ + A +QL SA+ +L +VH ++ N+LL Sbjct 145 GGNLMHKIY-EKKRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDN----- 198 Query 752 SPFIKLSDPGV----GLGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 IKL D G+ G+ S + + APE L +D W G + Sbjct 199 --NIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA--RKKYGPKIDVWSIGVNMY 254 Query 806 EICFDGEAPL----QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861 + G P S ++ + + LP L +P +RP+ + Sbjct 255 AML-TGTLPFTVEPFSLRALYQKMVDKAMNPLPTQLSTGAVNFLRSLLEPDPVKRPNIQQ 313 Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 L + + + V + S + L LG Sbjct 314 ALANRWLNENYTGKVPCNVTYPNRISLEDLSPSVVLHMTEKLGY 357 >sp|Q9IA88|SIK2_CHICK Serine/threonine-protein kinase SIK2 OS=Gallus gallus OX=9031 GN=SIK2 PE=2 SV=1 Length=798 Score = 227 bits (578), Expect = 1e-60, Method: Composition-based stats. Identities = 67/273 (25%), Positives = 110/273 (40%), Gaps = 29/273 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTL 954 + R LG+G+F V L + T VA+K + K P + +E+ I++ L Sbjct 25 FYDIERTLGKGNFAVVKL----ARHRVTKTQVAIKIIDKTRLDPSNLEKIYREVQIMKLL 80 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAY 1013 H HIIK E + L +V E+ G + D+L + + ++ QI + Y Sbjct 81 NHPHIIKLYQVMETKD--MLYIVTEFAKNGEMFDHLTSNGHLSESEARKKFWQILSAVEY 138 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 H+ H +HRDL N+LLD + +K+ DFG G + SP + APE Sbjct 139 CHSHHIVHRDLKTENLLLDANMNIKLADFGFGNFYKSGEP---LSTWCGSPP-YAAPEVF 194 Query 1074 KEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + ++ D+WS GV LY L+ P + L + + G Sbjct 195 EGKEYEGPHLDIWSLGVVLYVLVCGSLPFDGP---------------NLPTLRQRVLEG- 238 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 R P + L++ + + R T + Sbjct 239 RFRIPYFMSEDCETLIRRMLVVDPTKRITISQI 271 Score = 201 bits (512), Expect = 3e-52, Method: Composition-based stats. Identities = 65/350 (19%), Positives = 122/350 (35%), Gaps = 40/350 (11%) Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 +++ AS + +Q RV +I LG+G V R RV Sbjct 1 MVIMSEDASVPAPSAAQPRPLRVGFYDIE--RTLGKGNFAVVKLARHRV----------- 47 Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVR 679 + +V +K++D + D + Y +M ++H H+ ++ V Sbjct 48 -------------TKTQVAIKIIDKTRLDPSNLEKIYREVQIMKLLNHPHIIKLYQVMET 94 Query 680 GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRN 739 +VTE+ ++G + L GH+ + Q+ SA+ Y + ++VH ++ N Sbjct 95 KDMLYIVTEFAKNGEMFDHLTSN-GHLSESEARKKFWQILSAVEYCHSHHIVHRDLKTEN 153 Query 740 ILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAMD 796 +LL + IKL+D G G P+ APE G +D Sbjct 154 LLLD-------ANMNIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYE-GPHLD 205 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 W G L + P+ ++ + + R+P TL + L +PT+R Sbjct 206 IWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPYFMSEDCETLIRRMLVVDPTKR 265 Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906 + I + +L +++ + + G Sbjct 266 ITISQIKQHKWMQADPSLRQQQSLSFSMQNYNSNLGDYNEQVLGIMQTLG 315 >sp|Q8AXB4|PAK3_XENLA Serine/threonine-protein kinase PAK 3 OS=Xenopus laevis OX=8355 GN=pak3 PE=2 SV=1 Length=564 Score = 221 bits (564), Expect = 1e-60, Method: Composition-based stats. Identities = 70/330 (21%), Positives = 124/330 (38%), Gaps = 26/330 (8%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 S T+ R+ R + + + + K+ + +G+G G V Sbjct 245 NSNSSTSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV-- 302 Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 Y + TG+ VA+K + P+ + EI ++R + +I+ Y E Sbjct 303 --YTAIDIATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVGDE-- 357 Query 974 LQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033 L +VMEY+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+LL Sbjct 358 LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGM 417 Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 D VK+ DFG + R +W APE + + D+WS G+ E Sbjct 418 DGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIE 474 Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 ++ PP + T L P++ + C E Sbjct 475 MV-----EGEPPYLNENPLRALYLIATNGT--------PELQNPERLSAIFRDFLNRCLE 521 Query 1154 TEASFRPTFENLI--PILKTVHEKYQGQAP 1181 + R + + L+ P LK + + P Sbjct 522 MDVDRRGSAKELLQHPFLK-IAKPLSSLTP 550 Score = 183 bits (464), Expect = 1e-47, Method: Composition-based stats. Identities = 63/340 (19%), Positives = 111/340 (33%), Gaps = 57/340 (17%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRV------------DQKEITQLSHL 595 PQP E SN R + R S+++ + +K+ T+ + Sbjct 236 TSPVTPQP-ENSNSSTSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKI 294 Query 596 GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF 655 GQG VY D V +K ++ Sbjct 295 GQGASGTVY------------------------TAIDIATGQEVAIKQMNLQQQPKKELI 330 Query 656 YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVA 715 +M + + ++ + G E +V EY+ G L + + V Sbjct 331 INEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TETCMDEGQIAAVC 388 Query 716 QQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREE 771 ++ AL +L + ++H ++ NILL G +KL+D G R Sbjct 389 RECLQALDFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCAQITPEQSKRST 441 Query 772 RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 V W+APE + A +D W G +E+ +GE P + +P + Sbjct 442 MVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNG 498 Query 832 RL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 PE ++CL + +R S + +L+ Sbjct 499 TPELQNPERLSAIFRDFLNRCLEMDVDRRGSAKELLQHPF 538 >sp|C0LGW2|PAM74_ARATH Probable LRR receptor-like serine/threonine-protein kinase PAM74 OS=Arabidopsis thaliana OX=3702 GN=PAM74 PE=1 SV=1 Length=884 Score = 228 bits (581), Expect = 1e-60, Method: Composition-based stats. Identities = 67/254 (26%), Positives = 115/254 (45%), Gaps = 12/254 (5%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 E VAVK L Q +K E+D+L ++H +++ G C+++ L L+ E++P G Sbjct 602 EQVAVKVLSQSSS-QGYKHFKAEVDLLLRVHHTNLVSLVGYCDERDH--LALIYEFLPKG 658 Query 985 SLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLV 1037 LR +L S I L A + G+ YLH+ +HRD+ N+LLD Sbjct 659 DLRQHLSGKSGGSFINWGNRLRIALEAALGLEYLHSGCTPPIVHRDIKTTNILLDEQLKA 718 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 K+ DFGL+++ P G E + +P + PE + + SDV+SFG+ L E++T+ Sbjct 719 KLADFGLSRSFPIGGETHISTVVAGTP-GYLDPEYYQTTRLGEKSDVYSFGIVLLEIITN 777 Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157 +K + ++T +T++++ + V L +C + Sbjct 778 QPVIDQSRSK-SHISQWVGFELTRGDITKIMDPNLNGDYESRSVWRVLELAMSCANPSSV 836 Query 1158 FRPTFENLIPILKT 1171 RP + LK Sbjct 837 NRPNMSQVANELKE 850 Score = 192 bits (488), Expect = 6e-49, Method: Composition-based stats. Identities = 58/251 (23%), Positives = 89/251 (35%), Gaps = 35/251 (14%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +KVL S F L+ +V HT+L + G C ++ E++ G L Sbjct 603 QVAVKVLSQSSSQGYKHFKAEVDLLLRVHHTNLVSLVGYCDERDHLALIYEFLPKGDLRQ 662 Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTS 752 L + G + W ++ +A + A L YL + +VH ++ NILL A Sbjct 663 HLSGKSGGSFINWGNRLRIALEAALGLEYLHSGCTPPIVHRDIKTTNILLDEQLKA---- 718 Query 753 PFIKLSDPGVGLG------ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 KL+D G+ +L PE L D + FG LLE Sbjct 719 ---KLADFGLSRSFPIGGETHISTVVAGTPGYLDPEYYQT--TRLGEKSDVYSFGIVLLE 773 Query 807 ICFDGEAPLQSRS---PSEKEHFYQRQHRLPEPSCPQLA------------TLTSQCLTY 851 I + QSRS S+ F + + + P L L C Sbjct 774 IITNQPVIDQSRSKSHISQWVGFELTRGDITKIMDPNLNGDYESRSVWRVLELAMSCANP 833 Query 852 EPTQRPSFRTI 862 RP+ + Sbjct 834 SSVNRPNMSQV 844 >sp|Q6CVA2|STE20_KLULA Serine/threonine-protein kinase STE20 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=STE20 PE=3 SV=1 Length=989 Score = 229 bits (585), Expect = 1e-60, Method: Composition-based stats. Identities = 65/282 (23%), Positives = 121/282 (43%), Gaps = 25/282 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G G V Y GT VA+K + + P+ + EI +++ H +I+ Sbjct 703 KIGQGASGGV----YTAYELGTNASVAIKQMNLEKQPK-KELIVNEILVMKGSKHNNIVN 757 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 + +G+ L +VMEY+ GSL D + + Q+ +++ +G+ +LH++ IH Sbjct 758 FIDSYLFRGD--LWVVMEYMEGGSLTDVVTHCILTEGQIGAVSRETLKGLQFLHSKGVIH 815 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RD+ + N+LL + +K+ DFG + +E R +W APE + ++ Sbjct 816 RDIKSDNILLSMNGDIKLTDFGFCAQI---NEVNLKRTTMVGTPYWMAPEVVSRKEYGPK 872 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 D+WS G+ + E++ + T L IA +L P Sbjct 873 VDIWSLGIMIIEMI-EGEPPYLNETPLRALYLIATNGTP------------KLKDPGNLS 919 Query 1142 CEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAP 1181 ++ + C + R T +L+ P + + E+ AP Sbjct 920 HKMAMFLNWCLMVDPEDRGTAADLLEDPFITEIAEENTSLAP 961 Score = 181 bits (458), Expect = 5e-45, Method: Composition-based stats. Identities = 51/271 (19%), Positives = 91/271 (34%), Gaps = 44/271 (16%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 +GQG VY + G V +K ++ Sbjct 703 KIGQGASGGVY------------------------TAYELGTNASVAIKQMNLEKQPKKE 738 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 +M H ++ + + +V EY+E G L + + Sbjct 739 LIVNEILVMKGSKHNNIVNFIDSYLFRGDLWVVMEYMEGGSLTDVVTH--CILTEGQIGA 796 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSR 769 V+++ L +L +K ++H ++ NILL+ + IKL+D G L R Sbjct 797 VSRETLKGLQFLHSKGVIHRDIKSDNILLS-------MNGDIKLTDFGFCAQINEVNLKR 849 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 V W+APE + +D W G ++E+ +GE P + +P + Sbjct 850 TTMVGTPYWMAPEVVS--RKEYGPKVDIWSLGIMIIEMI-EGEPPYLNETPLRALYLIAT 906 Query 830 QHRL----PEPSCPQLATLTSQCLTYEPTQR 856 P ++A + CL +P R Sbjct 907 NGTPKLKDPGNLSHKMAMFLNWCLMVDPEDR 937 >sp|Q14012|KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 OS=Homo sapiens OX=9606 GN=CAMK1 PE=1 SV=1 Length=370 Score = 216 bits (549), Expect = 1e-60, Method: Composition-based stats. Identities = 66/289 (23%), Positives = 101/289 (35%), Gaps = 30/289 (10%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 P + LG G F +V L + T ++VA+K + + Sbjct 8 PRWKQAEDIRDIYDFRDVLGTGAFSEVIL----AEDKRTQKLVAIKCIAKEALEGKEGSM 63 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLF 1003 + EI +L + H +I+ E G L L+M+ V G L D + Sbjct 64 ENEIAVLHKIKHPNIVALDDIYESGGH--LYLIMQLVSGGELFDRIVEKGFYTERDASRL 121 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVL---LDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 Q+ + + YLH +HRDL N+L LD D + I DFGL+K G V Sbjct 122 IFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPG----SVLST 177 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 + APE L + + A D WS GV Y LL + Sbjct 178 ACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPF--------------YDEND 223 Query 1121 VLRLTELLERGERLPRP--DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 ++L+ P D +++ E + R T E + Sbjct 224 AKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQ 272 Score = 150 bits (378), Expect = 6e-38, Method: Composition-based stats. Identities = 41/284 (14%), Positives = 87/284 (31%), Gaps = 41/284 (14%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 LG G + V + D+ + V +K + + Sbjct 24 DVLGTGAFSEV------------------------ILAEDKRTQKLVAIKCIAKEALEGK 59 Query 653 L-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711 + +++ ++ H ++ + + G ++ + V G L + E+G Sbjct 60 EGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRI-VEKGFYTERDA 118 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-- 769 + Q+ A+ YL + +VH ++ N+L + I +SD G+ Sbjct 119 SRLIFQVLDAVKYLHDLGIVHRDLKPENLL----YYSLDEDSKIMISDFGLSKMEDPGSV 174 Query 770 -EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 ++APE L S A+D W G I G P + ++ Sbjct 175 LSTACGTPGYVAPEVLAQ--KPYSKAVDCWSIGVIAY-ILLCGYPPFYDENDAKLFEQIL 231 Query 829 R-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + + + +P +R + L+ Sbjct 232 KAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPW 275 >sp|Q63450|KCC1A_RAT Calcium/calmodulin-dependent protein kinase type 1 OS=Rattus norvegicus OX=10116 GN=Camk1 PE=1 SV=2 Length=374 Score = 216 bits (549), Expect = 1e-60, Method: Composition-based stats. Identities = 66/296 (22%), Positives = 102/296 (34%), Gaps = 30/296 (10%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + + P + LG G F +V L + T ++VA+K + Sbjct 1 MPGAVEGPRWKQAEDIRDIYDFRDVLGTGAFSEVIL----AEDKRTQKLVAIKCIAKKAL 56 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-G 996 + EI +L + H +I+ E G L L+M+ V G L D + Sbjct 57 EGKEGSMENEIAVLHKIKHPNIVALDDIYESGGH--LYLIMQLVSGGELFDRIVEKGFYT 114 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL---LDNDRLVKIGDFGLAKAVPEGHE 1053 Q+ + + YLH +HRDL N+L LD D + I DFGL+K G Sbjct 115 ERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPG-- 172 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 V + APE L + + A D WS GV Y LL Sbjct 173 --SVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPF------------ 218 Query 1114 IAQGQMTVLRLTELLERGERLPRP--DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + ++L+ P D +++ E + R T E + Sbjct 219 --YDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQ 272 Score = 150 bits (378), Expect = 5e-38, Method: Composition-based stats. Identities = 41/284 (14%), Positives = 87/284 (31%), Gaps = 41/284 (14%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 LG G + V + D+ + V +K + + Sbjct 24 DVLGTGAFSEV------------------------ILAEDKRTQKLVAIKCIAKKALEGK 59 Query 653 L-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711 + +++ ++ H ++ + + G ++ + V G L + E+G Sbjct 60 EGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRI-VEKGFYTERDA 118 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-- 769 + Q+ A+ YL + +VH ++ N+L + I +SD G+ Sbjct 119 SRLIFQVLDAVKYLHDLGIVHRDLKPENLL----YYSLDEDSKIMISDFGLSKMEDPGSV 174 Query 770 -EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 ++APE L S A+D W G I G P + ++ Sbjct 175 LSTACGTPGYVAPEVLAQ--KPYSKAVDCWSIGVIAY-ILLCGYPPFYDENDAKLFEQIL 231 Query 829 R-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + + + +P +R + L+ Sbjct 232 KAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPW 275 >sp|Q91YS8|KCC1A_MOUSE Calcium/calmodulin-dependent protein kinase type 1 OS=Mus musculus OX=10090 GN=Camk1 PE=1 SV=1 Length=374 Score = 216 bits (549), Expect = 1e-60, Method: Composition-based stats. Identities = 66/296 (22%), Positives = 102/296 (34%), Gaps = 30/296 (10%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + + P + LG G F +V L + T ++VA+K + Sbjct 1 MPGAVEGPRWKQAEDIRDIYDFRDVLGTGAFSEVIL----AEDKRTQKLVAIKCIAKKAL 56 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-G 996 + EI +L + H +I+ E G L L+M+ V G L D + Sbjct 57 EGKEGSMENEIAVLHKIKHPNIVALDDIYESGGH--LYLIMQLVSGGELFDRIVEKGFYT 114 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL---LDNDRLVKIGDFGLAKAVPEGHE 1053 Q+ + + YLH +HRDL N+L LD D + I DFGL+K G Sbjct 115 ERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPG-- 172 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 V + APE L + + A D WS GV Y LL Sbjct 173 --SVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPF------------ 218 Query 1114 IAQGQMTVLRLTELLERGERLPRP--DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + ++L+ P D +++ E + R T E + Sbjct 219 --YDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQ 272 Score = 150 bits (378), Expect = 5e-38, Method: Composition-based stats. Identities = 41/284 (14%), Positives = 87/284 (31%), Gaps = 41/284 (14%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 LG G + V + D+ + V +K + + Sbjct 24 DVLGTGAFSEV------------------------ILAEDKRTQKLVAIKCIAKKALEGK 59 Query 653 L-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711 + +++ ++ H ++ + + G ++ + V G L + E+G Sbjct 60 EGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRI-VEKGFYTERDA 118 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-- 769 + Q+ A+ YL + +VH ++ N+L + I +SD G+ Sbjct 119 SRLIFQVLDAVKYLHDLGIVHRDLKPENLL----YYSLDEDSKIMISDFGLSKMEDPGSV 174 Query 770 -EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 ++APE L S A+D W G I G P + ++ Sbjct 175 LSTACGTPGYVAPEVLAQ--KPYSKAVDCWSIGVIAY-ILLCGYPPFYDENDAKLFEQIL 231 Query 829 R-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + + + +P +R + L+ Sbjct 232 KAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPW 275 >sp|O19004|ARAF_PIG Serine/threonine-protein kinase A-Raf OS=Sus scrofa OX=9823 GN=ARAF PE=2 SV=1 Length=606 Score = 223 bits (567), Expect = 1e-60, Method: Composition-based stats. Identities = 75/326 (23%), Positives = 133/326 (41%), Gaps = 27/326 (8%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 + P ++ R + + + ++ ++ +G G FG V Sbjct 268 KSPHSKSPSEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 327 Query 915 CYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 + VAVK LK A + +K E+ +LR H +I+ + G G Sbjct 328 RWHG-------DVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG--- 377 Query 974 LQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031 ++ ++ SL +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L Sbjct 378 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 437 Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFG 1088 VKIGDFGLA V + E V W A E ++ + + SDV+++G Sbjct 438 HEGLTVKIGDFGLA-TVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYG 496 Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148 V LYEL+T ++ + + +G ++ CP + L+ Sbjct 497 VVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSK----------ISSNCPKAMRRLL 546 Query 1149 KNCWETEASFRPTFENLIPILKTVHE 1174 +C + + RP F ++ ++ + Sbjct 547 SDCLKFQREERPLFPQILATIELLQR 572 Score = 207 bits (528), Expect = 2e-55, Method: Composition-based stats. Identities = 71/366 (19%), Positives = 122/366 (33%), Gaps = 53/366 (14%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQL-SFHRVDQKEITQLSHLGQGTRTNVYEG 606 + P E + + + L + V E+ L +G G+ V+ G Sbjct 268 KSPHSKSPSEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 327 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH--HDIALAFYETASLMSQ 664 R + V +KVL + + A AF ++ + Sbjct 328 RWHGD---------------------------VAVKVLKVAQPTAEQAQAFKNEMQVLRK 360 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 H ++ G R ++T++ E L L M + VA+Q A + Y Sbjct 361 TRHVNILLFMGFMTRPG-FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDY 419 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778 L KN++H ++ NI L +K+ D G+ GA E+ + W Sbjct 420 LHAKNIIHRDLKSNNIFLHEGL-------TVKIGDFGLATVKTRWSGAQPLEQPSGSVLW 472 Query 779 LAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP- 836 +A E + N S D + +G L E+ G P ++ F + L Sbjct 473 MAAEVIRMQDPNPYSFQSDVYAYGVVLYELM-TGSLPYSHIGSRDQIIFMVGRGYLSPDL 531 Query 837 -----SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 +CP+ + L S CL ++ +RP F IL + LQ + + S Sbjct 532 SKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQA 591 Query 891 VFHKRY 896 Sbjct 592 DELPAC 597 >sp|Q6R2K3|SRF3_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 3 OS=Arabidopsis thaliana OX=3702 GN=SRF3 PE=1 SV=1 Length=776 Score = 226 bits (576), Expect = 1e-60, Method: Composition-based stats. Identities = 71/334 (21%), Positives = 134/334 (40%), Gaps = 21/334 (6%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 I+ ++ + + + + + + +G G G V Sbjct 450 IISPERPVKKTSPKRLPLTSVKHYSIASLQQYTESFAQENLIGSGMLGSVYRARL----- 504 Query 922 GTGEMVAVKALKADCGPQHRS-GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 G++ AVK L Q + + + ++ + + H +I++ G C + ++ LV EY Sbjct 505 PNGKLFAVKKLDKRASEQQQDHEFIELVNNIDMIRHSNIVELVGYCAEHDQR--LLVYEY 562 Query 981 VPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLD 1032 G+L+D L + + + A + YLH IHR+ + NVLLD Sbjct 563 CSNGTLQDGLHSDDEFKKKLSWNTRVSMALGAARALEYLHEVCEPPIIHRNFKSANVLLD 622 Query 1033 NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLY 1092 +D V + D GLA + G ++ + + APE + + SDV+SFGV + Sbjct 623 DDLSVLVSDCGLAPLISSG-SVSQLSGQLLAAYGYGAPE-FDSGIYTWQSDVYSFGVVML 680 Query 1093 ELLTHCDSSQSPPTKFLE-LIGIAQGQM-TVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 ELLT S ++ + L+ A Q+ + L ++++ P K ++ Sbjct 681 ELLTGRMSYDRDRSRGEQFLVRWAIPQLHDIDALGKMVDPSLNGQYPAKSLSHFADIISR 740 Query 1151 CWETEASFRPTFENLIP-ILKTVHEKYQGQAPSV 1183 C ++E FRP ++ +L + + G S Sbjct 741 CVQSEPEFRPLMSEVVQDLLDMIRRERHGSGDST 774 Score = 177 bits (448), Expect = 2e-44, Method: Composition-based stats. Identities = 62/346 (18%), Positives = 116/346 (34%), Gaps = 72/346 (21%) Query 567 ARASPRTLNLSQLSFHRVD-----QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 + SP+ L L+ + + + + Q + +G G +VY RL Sbjct 458 KKTSPKRLPLTSVKHYSIASLQQYTESFAQENLIGSGMLGSVYRARLPNGKLF------- 510 Query 622 DDEDPLVPGRDRGQELRVVLKVLDP--SHHDIALAFYETASLMSQVSHTHLAFVHGVCVR 679 +K LD S F E + + + H+++ + G C Sbjct 511 ------------------AVKKLDKRASEQQQDHEFIELVNNIDMIRHSNIVELVGYCAE 552 Query 680 GPENIMVTEYVEHGPLDVWLRRE---RGHVPMAWKMVVAQQLASALSYLE---NKNLVHG 733 + ++V EY +G L L + + + ++ +A A AL YL ++H Sbjct 553 HDQRLLVYEYCSNGTLQDGLHSDDEFKKKLSWNTRVSMALGAARALEYLHEVCEPPIIHR 612 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGG 787 N N+LL + +SD G+ S + + + APE Sbjct 613 NFKSANVLLD-------DDLSVLVSDCGLAPLISSGSVSQLSGQLLAAYGYGAPE---FD 662 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS---------- 837 + + D + FG +LE+ + + RS E+ +L + Sbjct 663 SGIYTWQSDVYSFGVVMLELLTGRMSYDRDRSRGEQFLVRWAIPQLHDIDALGKMVDPSL 722 Query 838 --------CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 A + S+C+ EP RP +++DL + Sbjct 723 NGQYPAKSLSHFADIISRCVQSEPEFRPLMSEVVQDLLDMIRRERH 768 >sp|Q6XHB2|ROCO4_DICDI Probable serine/threonine-protein kinase roco4 OS=Dictyostelium discoideum OX=44689 GN=roco4 PE=1 SV=1 Length=1726 Score = 232 bits (591), Expect = 1e-60, Method: Composition-based stats. Identities = 76/355 (21%), Positives = 133/355 (37%), Gaps = 54/355 (15%) Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY----------- 896 C+ P P + ++ LQ +P P + Sbjct 966 CVQKNPRADPYYFDFSSCISALQDGKPHLFCRNDPSIPVRIDYIAPDLCLKKVPTLADNE 1025 Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS------GWKQEIDI 950 ++ + +G+G FG V + +VA+K+L +++E+ I Sbjct 1026 IEYEKQIGKGGFGLV----HKGRLVKDKSVVAIKSLILGDSEGETEMIEKFQEFQREVFI 1081 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQIC 1008 + L H +I+K G + +VME+VP G L L H I + L I Sbjct 1082 MSNLNHPNIVKLYGLMHNPPR----MVMEFVPCGDLYHRLLDKAHPIKWSVKLRLMLDIA 1137 Query 1009 EGMAYLHAQH--YIHRDLAARNVLL---DNDRLV--KIGDFGLAKAVPEGHEYYRVREDG 1061 G+ Y+ Q+ +HRDL + N+ L D + V K+ DFGL+ + Sbjct 1138 LGIEYMQNQNPPIVHRDLRSPNIFLQSLDENAPVCAKVADFGLS------QQSVHSVSGL 1191 Query 1062 DSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 W APE + +E + +D +SF + LY +LT ++ I + + Sbjct 1192 LGNFQWMAPETIGAEEESYTEKADTYSFAMILYTILTGEGPFDEYSYGKIKFINMIR--- 1248 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 E G R P+ CP + ++++ CW + RP F ++ L + Sbjct 1249 ---------EEGLRPTIPEDCPPRLRNVIELCWSGDPKKRPHFSYIVKELSELRN 1294 Score = 223 bits (568), Expect = 8e-58, Method: Composition-based stats. Identities = 74/359 (21%), Positives = 127/359 (35%), Gaps = 48/359 (13%) Query 532 ALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPR-TLNLSQLSFHRVDQ---K 587 RA F C +L R L +V Sbjct 965 HCVQKNPRADPYYFDFSSCISALQDGKPHLFCRNDPSIPVRIDYIAPDLCLKKVPTLADN 1024 Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 EI +G+G V++GRL + S V +K L Sbjct 1025 EIEYEKQIGKGGFGLVHKGRLVKDKS------------------------VVAIKSLILG 1060 Query 648 HHDIA-------LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 + F +MS ++H ++ ++G+ P MV E+V G L L Sbjct 1061 DSEGETEMIEKFQEFQREVFIMSNLNHPNIVKLYGLMHNPPR--MVMEFVPCGDLYHRLL 1118 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + + + K+ + +A + Y++N+N +VH ++ NI L L E K++ Sbjct 1119 DKAHPIKWSVKLRLMLDIALGIEYMQNQNPPIVHRDLRSPNIFL--QSLDENAPVCAKVA 1176 Query 759 DPGVG-LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 D G+ S + W+APE + S + D + F L I GE P Sbjct 1177 DFGLSQQSVHSVSGLLGNFQWMAPETIGAEEESYTEKADTYSFAMILYTIL-TGEGPFDE 1235 Query 818 RSPSEKEHFYQR-----QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 S + + + +PE P+L + C + +P +RP F I+++L+ L+ Sbjct 1236 YSYGKIKFINMIREEGLRPTIPEDCPPRLRNVIELCWSGDPKKRPHFSYIVKELSELRN 1294 >sp|Q62829|PAK3_RAT Serine/threonine-protein kinase PAK 3 OS=Rattus norvegicus OX=10116 GN=Pak3 PE=1 SV=1 Length=544 Score = 221 bits (562), Expect = 1e-60, Method: Composition-based stats. Identities = 66/318 (21%), Positives = 120/318 (38%), Gaps = 23/318 (7%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 T + + T+ R+ R + + + + K+ + +G+G G Sbjct 221 TPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASG 280 Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 V Y + TG+ VA+K + P+ + EI ++R + +I+ Y Sbjct 281 TV----YTALDIATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVG 335 Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029 E L +VMEY+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+ Sbjct 336 DE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNI 393 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 LL D VK+ DFG + R +W APE + + D+WS G+ Sbjct 394 LLGMDGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGI 450 Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149 E++ PP + T L P++ + Sbjct 451 MAIEMV-----EGEPPYLNENPLRALYLIATNGT--------PELQNPERLSAVFRDFLN 497 Query 1150 NCWETEASFRPTFENLIP 1167 C E + R + + L+ Sbjct 498 RCLEMDVDRRGSAKELLQ 515 Score = 178 bits (451), Expect = 4e-46, Method: Composition-based stats. Identities = 54/291 (19%), Positives = 97/291 (33%), Gaps = 44/291 (15%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +K+ T+ +GQG VY D V +K + Sbjct 264 PKKKYTRFEKIGQGASGTVY------------------------TALDIATGQEVAIKQM 299 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + +M + + ++ + G E +V EY+ G L + Sbjct 300 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 357 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + V ++ AL +L + ++H ++ NILL G +KL+D G Sbjct 358 CMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 410 Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 R V W+APE + A +D W G +E+ +GE P + +P Sbjct 411 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENP 467 Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + PE ++CL + +R S + +L+ Sbjct 468 LRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPF 518 >sp|Q39193|SRK2I_ARATH Serine/threonine-protein kinase SRK2I OS=Arabidopsis thaliana OX=3702 GN=SRK2I PE=1 SV=1 Length=361 Score = 215 bits (547), Expect = 1e-60, Method: Composition-based stats. Identities = 69/282 (24%), Positives = 119/282 (42%), Gaps = 26/282 (9%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQE 947 P + ++D+G G+FG L + T E+VAVK + + G + ++E Sbjct 13 MPIMHDSDRYDFVKDIGSGNFGVARLM----RDKLTKELVAVKYI--ERGDKIDENVQRE 66 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQ 1006 I R+L H +I+++K L ++MEY G L + + + F QQ Sbjct 67 IINHRSLRHPNIVRFKEVILTPTH--LAIIMEYASGGELYERICNAGRFSEDEARFFFQQ 124 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 + G++Y H+ HRDL N LLD +KI DFG +K + + + +P Sbjct 125 LLSGVSYCHSMQICHRDLKLENTLLDGSPAPRLKICDFGYSK---SSVLHSQPKSTVGTP 181 Query 1065 VFWYAPECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 + APE L ++ +DVWS GVTLY +L + P + + Sbjct 182 A-YIAPEVLLRQEYDGKIADVWSCGVTLYVMLVGAYPFEDPE----------EPRDYRKT 230 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + +L +P + E HL+ + + + R + + Sbjct 231 IQRILSVKYSIPDDIRISPECCHLISRIFVADPATRISIPEI 272 Score = 161 bits (408), Expect = 5e-42, Method: Composition-based stats. Identities = 54/329 (16%), Positives = 97/329 (29%), Gaps = 41/329 (12%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 D + +G G RD+ + V +K + Sbjct 18 DSDRYDFVKDIGSGNFG------------------------VARLMRDKLTKELVAVKYI 53 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + I + H ++ V + ++ EY G L + G Sbjct 54 ERGDK-IDENVQREIINHRSLRHPNIVRFKEVILTPTHLAIIMEYASGGELYERI-CNAG 111 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 QQL S +SY + + H ++ N LL +P +K+ D G Sbjct 112 RFSEDEARFFFQQLLSGVSYCHSMQICHRDLKLENTLLD-----GSPAPRLKICDFGYSK 166 Query 765 GAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 ++ + V ++APE L D W G TL + P Sbjct 167 SSVLHSQPKSTVGTPAYIAPEVLLRQEYD-GKIADVWSCGVTLYVMLVGAYPFEDPEEPR 225 Query 822 EKEHFYQR----QHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + QR ++ +P+ P+ L S+ +P R S I L+ Sbjct 226 DYRKTIQRILSVKYSIPDDIRISPECCHLISRIFVADPATRISIPEIKTHSWFLKNLPAD 285 Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 + N S +P + ++ + Sbjct 286 LMNESNTGSQFQEPEQPMQSLDTIMQIIS 314 >sp|Q9FYK0|TMK2_ARATH Receptor-like kinase TMK2 OS=Arabidopsis thaliana OX=3702 GN=TMK2 PE=1 SV=1 Length=886 Score = 228 bits (581), Expect = 1e-60, Method: Composition-based stats. Identities = 71/281 (25%), Positives = 116/281 (41%), Gaps = 22/281 (8%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRT 953 + LG G FG V G +AVK +++ + +K EI +L Sbjct 545 YNFDEKNILGRGGFGIVYKGEL-----HDGTKIAVKRMESSIISGKGLDEFKSEIAVLTR 599 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP------RHSIGLAQLLLFAQQI 1007 + H +++ G C + E+ LV +Y+P G+L ++ + + L+ A + Sbjct 600 VRHRNLVVLHGYCLEGNER--LLVYQYMPQGTLSRHIFYWKEEGLRPLEWTRRLIIALDV 657 Query 1008 CEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 G+ YLH Q +IHRDL N+LL +D K+ DFGL + PEG + + G Sbjct 658 ARGVEYLHTLAHQSFIHRDLKPSNILLGDDMHAKVADFGLVRLAPEGTQSIETKIAG--T 715 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 + APE + DV+SFGV L ELLT + ++ + +M + + Sbjct 716 FGYLAPEYAVTGRVTTKVDVYSFGVILMELLTGRKALDVARSEEEVHLATWFRRMFINKG 775 Query 1125 TELLERGERLPRPDKCPCE---VYHLMKNCWETEASFRPTF 1162 + E + ++ V L C E RP Sbjct 776 SFPKAIDEAMEVNEETLRSINIVAELANQCSSREPRDRPDM 816 Score = 217 bits (552), Expect = 6e-57, Method: Composition-based stats. Identities = 67/312 (21%), Positives = 125/312 (40%), Gaps = 67/312 (21%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 R + + LG+G VY+G L ++ +K Sbjct 541 RDATYNFDEKNILGRGGFGIVYKGELHDG-------------------------TKIAVK 575 Query 643 VLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 ++ S F +++++V H +L +HG C+ G E ++V +Y+ G L + Sbjct 576 RMESSIISGKGLDEFKSEIAVLTRVRHRNLVVLHGYCLEGNERLLVYQYMPQGTLSRHIF 635 Query 701 --RERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSP 753 +E G P+ W ++++A +A + YL +++ +H ++ NILL G Sbjct 636 YWKEEGLRPLEWTRRLIIALDVARGVEYLHTLAHQSFIHRDLKPSNILL-------GDDM 688 Query 754 FIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 K++D G+ A + + +LAPE G ++T +D + FG L+E+ Sbjct 689 HAKVADFGLVRLAPEGTQSIETKIAGTFGYLAPEYAVTG--RVTTKVDVYSFGVILMELL 746 Query 809 FDGEAPLQSRSPSEKEHF-YQRQHRLPEPSCPQ------------------LATLTSQCL 849 +A +RS E + R+ + + S P+ +A L +QC Sbjct 747 TGRKALDVARSEEEVHLATWFRRMFINKGSFPKAIDEAMEVNEETLRSINIVAELANQCS 806 Query 850 TYEPTQRPSFRT 861 + EP RP Sbjct 807 SREPRDRPDMNH 818 >sp|Q9FX43|M2K9_ARATH Mitogen-activated protein kinase kinase 9 OS=Arabidopsis thaliana OX=3702 GN=MKK9 PE=1 SV=1 Length=310 Score = 213 bits (543), Expect = 1e-60, Method: Composition-based stats. Identities = 75/311 (24%), Positives = 127/311 (41%), Gaps = 25/311 (8%) Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920 + L + + + + + L+K+ LG G+ G V Y + Sbjct 11 NLRLPLPPISDRRFSTSSSSATTTTVAGCNGISACDLEKLNVLGCGNGGIV----YKVRH 66 Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 T E+ A+K + D P +E++ILR +++K G E + ++MEY Sbjct 67 KTTSEIYALKTVNGDMDPIFTRQLMREMEILRRTDSPYVVKCHGIFEKPVVGEVSILMEY 126 Query 981 VPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIG 1040 + G+L R + +L FA+QI +G++YLHA +HRD+ N+LL++ VKI Sbjct 127 MDGGTLESL--RGGVTEQKLAGFAKQILKGLSYLHALKIVHRDIKPANLLLNSKNEVKIA 184 Query 1041 DFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-----YASDVWSFGVTLYELL 1095 DFG++K + + + +PE YA D+WSFG+ + ELL Sbjct 185 DFGVSKILVRSLD---SCNSYVGTCAYMSPERFDSESSGGSSDIYAGDIWSFGLMMLELL 241 Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETE 1155 P + L + GE P+ C E ++ C + Sbjct 242 VGHFPLLPPGQR-----------PDWATLMCAVCFGEPPRAPEGCSEEFRSFVECCLRKD 290 Query 1156 ASFRPTFENLI 1166 +S R T L+ Sbjct 291 SSKRWTAPQLL 301 Score = 163 bits (412), Expect = 4e-43, Method: Composition-based stats. Identities = 57/295 (19%), Positives = 102/295 (35%), Gaps = 50/295 (17%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 ++ +L+ LG G VY+ R + + D DP+ Sbjct 46 DLEKLNVLGCGNGGIVYKVRHKTTSEIYALKTVNGDMDPIF------------------- 86 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRG--PENIMVTEYVEHGPLDVWLRRERGH 705 ++ + ++ HG+ + E ++ EY++ G L+ RG Sbjct 87 ----TRQLMREMEILRRTDSPYVVKCHGIFEKPVVGEVSILMEYMDGGTLESL----RGG 138 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763 V A+Q+ LSYL +VH ++ N+LL +K++D GV Sbjct 139 VTEQKLAGFAKQILKGLSYLHALKIVHRDIKPANLLLNSKNE-------VKIADFGVSKI 191 Query 764 --LGALSREERVERIPWLAPECLPGGANSLST---AMDKWGFGATLLEICFDGEAP--LQ 816 S V +++PE ++ S+ A D W FG +LE+ G P Sbjct 192 LVRSLDSCNSYVGTCAYMSPERFDSESSGGSSDIYAGDIWSFGLMMLELLV-GHFPLLPP 250 Query 817 SRSPSEKEHFY----QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P R PE + + CL + ++R + +L Sbjct 251 GQRPDWATLMCAVCFGEPPRAPEGCSEEFRSFVECCLRKDSSKRWTAPQLLAHPF 305 >sp|P53666|LIMK2_CHICK LIM domain kinase 2 OS=Gallus gallus OX=9031 GN=LIMK2 PE=2 SV=1 Length=642 Score = 223 bits (568), Expect = 1e-60, Method: Composition-based stats. Identities = 77/302 (25%), Positives = 129/302 (43%), Gaps = 38/302 (13%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 +F L LG+G FG+ T+ TG+++ +K L C + + + E+ Sbjct 323 QQIFRPCDLIHGEVLGKGFFGQ----AIKVTHKATGKVMVMKEL-IRCDEETQKTFLTEV 377 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQI 1007 ++R+L H +++K+ G +K L L+ EY+ G+L+D+L Q + FA+ I Sbjct 378 KVMRSLDHPNVLKFIGVLYK--DKKLNLLTEYIEGGTLKDFLRNADPFPWQQKVSFAKGI 435 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV---------- 1057 GMAYLH+ IHRDL + N L+ D+ V + DFGL++ + E + + Sbjct 436 ASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKKPTLEKPSAKKRTL 495 Query 1058 -------REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 R +W APE L + D++SFG+ L E++ + + L+ Sbjct 496 RKSDRKKRYTVVGNPYWMAPEMLNGQSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLD 555 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 G L + + P CP + L C E RP F L + Sbjct 556 F-----GLNVKLFWEKFV--------PADCPPAFFPLAAICCRLEPESRPPFSKLEDSFE 602 Query 1171 TV 1172 + Sbjct 603 AL 604 Score = 196 bits (499), Expect = 2e-51, Method: Composition-based stats. Identities = 65/349 (19%), Positives = 112/349 (32%), Gaps = 63/349 (18%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 + P E L++ R S + S S ++ LG+G + Sbjct 292 KSPGPSSPKEP--LLLSRDISRSESLRSSSSCSQQIFRPCDLIHGEVLGKGFFGQAIKVT 349 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667 + G +V+K L + F +M + H Sbjct 350 HKATGK------------------------VMVMKELIRCDEETQKTFLTEVKVMRSLDH 385 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 ++ GV + + ++TEY+E G L +LR P K+ A+ +AS ++YL + Sbjct 386 PNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRNAD-PFPWQQKVSFAKGIASGMAYLHS 444 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----------------------- 764 ++H ++ N L+ + ++D G+ Sbjct 445 MCIIHRDLNSHNCLI-------KLDKTVVVADFGLSRLIVEERKKPTLEKPSAKKRTLRK 497 Query 765 -GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--FDGEAPLQSRSPS 821 R V W+APE L G S +D + FG L EI + R+ Sbjct 498 SDRKKRYTVVGNPYWMAPEMLNG--QSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLD 555 Query 822 EKEHFY-QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + + +P P L + C EP RP F + L Sbjct 556 FGLNVKLFWEKFVPADCPPAFFPLAAICCRLEPESRPPFSKLEDSFEAL 604 >sp|Q96TL5|HOG1_NEUCR Mitogen-activated protein kinase hog-1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=hog-1 PE=1 SV=1 Length=358 Score = 215 bits (547), Expect = 2e-60, Method: Composition-based stats. Identities = 65/284 (23%), Positives = 108/284 (38%), Gaps = 29/284 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VA+K + K P +E+ +L+ L HE++ Sbjct 24 QPVGMGAFGLVC----SAKDQLTNQNVAIKKIMKPFSTPVLAKRTYRELKLLKHLRHENV 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L + ER P + L++ + R T + Sbjct 252 SLPKRERQPLKNKFKNADSSAVDLLERMLVFDPKKRITATEALS 295 Score = 129 bits (324), Expect = 5e-31, Method: Composition-based stats. Identities = 36/231 (16%), Positives = 75/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E D + M + +D+ V +K ++ P +A Y Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSAKDQLTNQNVAIKKIMKPFSTPVLAKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo sapiens OX=9606 GN=NUAK2 PE=1 SV=1 Length=628 Score = 223 bits (567), Expect = 2e-60, Method: Composition-based stats. Identities = 69/291 (24%), Positives = 116/291 (40%), Gaps = 32/291 (11%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-- 936 + + + LG+G +GKV + +G +VA+K+++ D Sbjct 35 MKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKAR-----ESSGRLVAIKSIRKDKIK 89 Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSI 995 Q ++EI+I+ +L H HII E+ + + +VMEY G L DY+ R + Sbjct 90 DEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSK--IVIVMEYASRGDLYDYISERQQL 147 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + F +QI + Y H +HRDL N+LLD + +KI DFGL+ +G Sbjct 148 SEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQG---- 203 Query 1056 RVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + + + +PE + + D WS GV LY L+ K Sbjct 204 KFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKI------ 257 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L + + G P P + L++ + R T E++ Sbjct 258 ---------LVKQISNGAYREPPK--PSDACGLIRWLLMVNPTRRATLEDV 297 Score = 174 bits (441), Expect = 4e-44, Method: Composition-based stats. Identities = 59/330 (18%), Positives = 98/330 (30%), Gaps = 45/330 (14%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEIT----QLSHLGQGTRTNV 603 RR + G SP+ L Q + + L LG+GT V Sbjct 8 RRSGPTPSAAELARPLAEGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKV 67 Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETAS 660 + R V +K + + Sbjct 68 KKAR-------------------------ESSGRLVAIKSIRKDKIKDEQDLMHIRREIE 102 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 +MS ++H H+ +H V + ++V EY G L ++ ER + +Q+ S Sbjct 103 IMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYI-SERQQLSEREARHFFRQIVS 161 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIP 777 A+ Y +VH ++ NILL + IK++D G+ + Sbjct 162 AVHYCHQNRVVHRDLKLENILLD-------ANGNIKIADFGLSNLYHQGKFLQTFCGSPL 214 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS 837 + +PE + G + +D W G L I G P P Sbjct 215 YASPEIVNGKPYT-GPEVDSWSLGVLLY-ILVHGTMPFDGHDHKILVKQISNGAYREPPK 272 Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 L L PT+R + + Sbjct 273 PSDACGLIRWLLMVNPTRRATLEDVASHWW 302 >sp|Q9C7T7|CEPR2_ARATH Receptor protein-tyrosine kinase CEPR2 OS=Arabidopsis thaliana OX=3702 GN=CEPR2 PE=1 SV=1 Length=977 Score = 229 bits (583), Expect = 2e-60, Method: Composition-based stats. Identities = 76/301 (25%), Positives = 123/301 (41%), Gaps = 23/301 (8%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 + V L + +G G GKV G VAVK LK G + Sbjct 670 FHQMELDVDEICRLDEDHVIGSGSAGKVYRVDLKKG----GGTVAVKWLKRGGGEEGDGT 725 Query 944 WK--QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH------SI 995 E++IL + H +++K C +G + LV E++ G+L L + + Sbjct 726 EVSVAEMEILGKIRHRNVLKLYACLVGRGSR--YLVFEFMENGNLYQALGNNIKGGLPEL 783 Query 996 GLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 + A +G+AYLH IHRD+ + N+LLD D KI DFG+AK +G+ Sbjct 784 DWLKRYKIAVGAAKGIAYLHHDCCPPIIHRDIKSSNILLDGDYESKIADFGVAKVADKGY 843 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI 1112 E+ V + APE +K SDV+SFGV L EL+T + + +++ Sbjct 844 EWSCVA----GTHGYMAPELAYSFKATEKSDVYSFGVVLLELVTGLRPMEDEFGEGKDIV 899 Query 1113 GIAQGQM--TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 Q+ L +L++ ++ V + C + RP+ ++ L Sbjct 900 DYVYSQIQQDPRNLQNVLDKQVLSTYIEESMIRVLKMGLLCTTKLPNLRPSMREVVRKLD 959 Query 1171 T 1171 Sbjct 960 D 960 Score = 175 bits (444), Expect = 2e-43, Method: Composition-based stats. Identities = 51/289 (18%), Positives = 100/289 (35%), Gaps = 47/289 (16%) Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRT 601 F+LR + S + A A + + Q+ + + + +G G+ Sbjct 636 SGLFALRYRVVKIRELDSENRDINKADAKWKIASFHQMELDVDEICRLDEDHVIGSGSAG 695 Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF---YET 658 VY L+ G V +K L + Sbjct 696 KVYRVDLKKGGG------------------------TVAVKWLKRGGGEEGDGTEVSVAE 731 Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-RGHVP-MAW--KMVV 714 ++ ++ H ++ ++ V +V E++E+G L L +G +P + W + + Sbjct 732 MEILGKIRHRNVLKLYACLVGRGSRYLVFEFMENGNLYQALGNNIKGGLPELDWLKRYKI 791 Query 715 AQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---GALS 768 A A ++YL + ++H ++ NILL + K++D GV Sbjct 792 AVGAAKGIAYLHHDCCPPIIHRDIKSSNILLDGDYES-------KIADFGVAKVADKGYE 844 Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 ++APE + + D + FG LLE+ G P++ Sbjct 845 WSCVAGTHGYMAPELA--YSFKATEKSDVYSFGVVLLELV-TGLRPMED 890 >sp|Q702W0|HOG1_BLAAD Mitogen-activated protein kinase hog1 OS=Blastobotrys adeninivorans OX=409370 GN=hog1 PE=1 SV=1 Length=400 Score = 216 bits (550), Expect = 2e-60, Method: Composition-based stats. Identities = 67/307 (22%), Positives = 111/307 (36%), Gaps = 37/307 (12%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQ 939 + + +G G FG V + T + VA+K + K P Sbjct 4 FIRTQIFGTCFEITSRYVDLNPVGMGAFGLVC----SARDQLTNQNVAIKKIMKPFSTPV 59 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ 999 +E+ +L+ L HE++I E + V E + L L + Sbjct 60 LAKRTYRELKLLKHLRHENLITLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEHQF 117 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 + F QI G+ Y+H+ +HRDL N+L++ + +KI DFGLA+ Y Sbjct 118 IQYFLYQILRGLKYVHSAGVVHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY---- 173 Query 1060 DGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ---------------- 1102 S ++ APE + K+ D+WS G E+L Sbjct 174 --VSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMLRGKPLFPGKDHVHQFSIITELLG 231 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP---CEVYHLMKNCWETEASFR 1159 +PP +E IG L + L + ER+P K P + L++ + R Sbjct 232 NPPDDVIETIGSEN----TLNFVKSLPKRERIPLSQKFPNADPDAVDLLEKMLVFDPRKR 287 Query 1160 PTFENLI 1166 + + Sbjct 288 INAADAL 294 Score = 132 bits (332), Expect = 9e-32, Method: Composition-based stats. Identities = 37/213 (17%), Positives = 69/213 (32%), Gaps = 18/213 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + RD+ V +K ++ P +A Y Sbjct 10 FGTCFEITSRYVDLNPVGMGAF---GLVCSARDQLTNQNVAIKKIMKPFSTPVLAKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H +L + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENLITLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEHQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + APE + +D W G E+ Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML 208 >sp|Q9FLV4|Y5248_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At5g24080 OS=Arabidopsis thaliana OX=3702 GN=At5g24080 PE=2 SV=1 Length=872 Score = 228 bits (580), Expect = 2e-60, Method: Composition-based stats. Identities = 65/300 (22%), Positives = 122/300 (41%), Gaps = 19/300 (6%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 + LG G FG V +VAVK L R + Sbjct 520 FTYRDLQNCTNNFSQLLGSGGFGTVYKGTVAGE-----TLVAVKRLDRALSHGERE-FIT 573 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLL 1001 E++ + +++H ++++ G C + + LV EY+ GSL ++ + Sbjct 574 EVNTIGSMHHMNLVRLCGYCSEDSHR--LLVYEYMINGSLDKWIFSSEQTANLLDWRTRF 631 Query 1002 LFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 A +G+AY H Q IH D+ N+LLD++ K+ DFGLAK + G E+ V Sbjct 632 EIAVATAQGIAYFHEQCRNRIIHCDIKPENILLDDNFCPKVSDFGLAKMM--GREHSHVV 689 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQG 1117 + APE + +DV+S+G+ L E++ + S + G A Sbjct 690 TMIRGTRGYLAPEWVSNRPITVKADVYSYGMLLLEIVGGRRNLDMSYDAEDFFYPGWAYK 749 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 ++T + +++ + ++ + + C + E S RP+ ++ +L+ ++ Sbjct 750 ELTNGTSLKAVDKRLQGVAEEEEVVKALKVAFWCIQDEVSMRPSMGEVVKLLEGTSDEIN 809 Score = 192 bits (488), Expect = 5e-49, Method: Composition-based stats. Identities = 61/327 (19%), Positives = 110/327 (34%), Gaps = 55/327 (17%) Query 517 EGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNL 576 G + + + L L ++L R + ++LI+ SP + Sbjct 467 HGLRQKVLVIPIVVGMLVLVALLGMLLYYNLDRKRTLKRAAKNSLILC----DSPVSFTY 522 Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 L +QL LG G VY+G + E Sbjct 523 RDLQNC---TNNFSQL--LGSGGFGTVYKGTVAG-------------------------E 552 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +K LD + F + + + H +L + G C ++V EY+ +G LD Sbjct 553 TLVAVKRLDRALSHGEREFITEVNTIGSMHHMNLVRLCGYCSEDSHRLLVYEYMINGSLD 612 Query 697 VWLRRER---GHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEG 750 W+ + + +A A ++Y + ++H ++ NILL Sbjct 613 KWIFSSEQTANLLDWRTRFEIAVATAQGIAYFHEQCRNRIIHCDIKPENILLD------- 665 Query 751 TSPFIKLSDPGVGLGALSREERVERI-----PWLAPECLPGGANSLSTAMDKWGFGATLL 805 + K+SD G+ V + +LAPE + ++ D + +G LL Sbjct 666 DNFCPKVSDFGLAKMMGREHSHVVTMIRGTRGYLAPEWVSN--RPITVKADVYSYGMLLL 723 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHR 832 EI G L +E + ++ Sbjct 724 EIV-GGRRNLDMSYDAEDFFYPGWAYK 749 >sp|Q5R7G9|NUAK2_PONAB NUAK family SNF1-like kinase 2 OS=Pongo abelii OX=9601 GN=NUAK2 PE=2 SV=1 Length=628 Score = 223 bits (567), Expect = 2e-60, Method: Composition-based stats. Identities = 69/291 (24%), Positives = 116/291 (40%), Gaps = 32/291 (11%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-- 936 + + + LG+G +GKV + +G +VA+K+++ D Sbjct 35 MKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKAR-----ESSGRLVAIKSIRKDKIK 89 Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSI 995 Q ++EI+I+ +L H HII E+ + + +VMEY G L DY+ R + Sbjct 90 DEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSK--IVIVMEYASRGDLYDYISERQQL 147 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + F +QI + Y H +HRDL N+LLD + +KI DFGL+ +G Sbjct 148 SEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQG---- 203 Query 1056 RVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + + + +PE + + D WS GV LY L+ K Sbjct 204 KFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKI------ 257 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L + + G P P + L++ + R T E++ Sbjct 258 ---------LVKQISNGAYREPPK--PSDACGLIRWLLMVNPTRRATLEDV 297 Score = 174 bits (441), Expect = 4e-44, Method: Composition-based stats. Identities = 59/330 (18%), Positives = 98/330 (30%), Gaps = 45/330 (14%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEIT----QLSHLGQGTRTNV 603 RR + G SP+ L Q + + L LG+GT V Sbjct 8 RRSGPTPSAAELARPLAEGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKV 67 Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETAS 660 + R V +K + + Sbjct 68 KKAR-------------------------ESSGRLVAIKSIRKDKIKDEQDLMHIRREIE 102 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLAS 720 +MS ++H H+ +H V + ++V EY G L ++ ER + +Q+ S Sbjct 103 IMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYI-SERQQLSEREARHFFRQIVS 161 Query 721 ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIP 777 A+ Y +VH ++ NILL + IK++D G+ + Sbjct 162 AVHYCHQNRVVHRDLKLENILLD-------ANGNIKIADFGLSNLYHQGKFLQTFCGSPL 214 Query 778 WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS 837 + +PE + G + +D W G L I G P P Sbjct 215 YASPEIVNGKPYT-GPEVDSWSLGVLLY-ILVHGTMPFDGHDHKILVKQISNGAYREPPK 272 Query 838 CPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 L L PT+R + + Sbjct 273 PSDACGLIRWLLMVNPTRRATLEDVASHWW 302 >sp|A9S9Q8|MPK4B_PHYPA Mitogen-activated protein kinase 4b OS=Physcomitrium patens OX=3218 GN=MPK4b PE=1 SV=1 Length=380 Score = 215 bits (548), Expect = 2e-60, Method: Composition-based stats. Identities = 77/324 (24%), Positives = 122/324 (38%), Gaps = 32/324 (10%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL- 932 + + ++Y+ IR +G G +G V N TGE VA+K + Sbjct 20 PTHNGEYTQYNIFGNLFEVSRKYVPPIRPIGRGAYGIVC----SAVNSETGEEVAIKKIG 75 Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL---QLVMEYVPLGSLRDY 989 A +EI +LR + HE+I+ + ++ +V E + L Sbjct 76 NAFDNRIDAKRTLREIKLLRHMDHENIVAIRDIIRPPTRENFNDVYIVYELMD-TDLHQI 134 Query 990 LP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + + F Q+ G+ Y+H+ +HRDL N+LL+ + +KI DFGLA+ Sbjct 135 IRSNQPLTEDHCQYFLYQLLRGLKYIHSAKVLHRDLKPSNLLLNANCDLKICDFGLARTT 194 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQSPPT- 1106 E + ++ APE L ++ A DVWS G ELL Sbjct 195 SETD----FMTEYVVTRWYRAPELLLNCSEYTAAIDVWSVGCIFMELLNREPLFPGRDYV 250 Query 1107 ----KFLELIGIAQGQ-------MTVLRLTELLERGERLPRPDKCP---CEVYHLMKNCW 1152 ELIG + R L R R P K P L+++ Sbjct 251 QQLRLITELIGSPEDHDLGFLRSDNARRYIRQLPRFARQPLDRKFPNMGPAAIDLVEHML 310 Query 1153 ETEASFRPTFENLI--PILKTVHE 1174 + + R T E + P L T+H+ Sbjct 311 RFDPARRITVEEALAHPYLATLHD 334 Score = 133 bits (334), Expect = 4e-32, Method: Composition-based stats. Identities = 37/236 (16%), Positives = 77/236 (33%), Gaps = 44/236 (19%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 V +K + + +G+G V G V +K Sbjct 37 EVSRKYVPPIRPIGRGAYGIVCSAVNSETGE------------------------EVAIK 72 Query 643 VLDPSHHDIALAF--YETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPL 695 + + + A L+ + H ++ + + + +V E ++ L Sbjct 73 KIGNAFDNRIDAKRTLREIKLLRHMDHENIVAIRDIIRPPTRENFNDVYIVYELMD-TDL 131 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + QL L Y+ + ++H ++ N+LL + + Sbjct 132 HQIIRSNQ-PLTEDHCQYFLYQLLRGLKYIHSAKVLHRDLKPSNLLLN-------ANCDL 183 Query 756 KLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 K+ D G+ + E V + APE L + + A+D W G +E+ Sbjct 184 KICDFGLARTTSETDFMTEYVVTRWYRAPELLLNCSE-YTAAIDVWSVGCIFMELL 238 >sp|Q54EY4|DST3_DICDI Serine/threonine-protein kinase dst3 OS=Dictyostelium discoideum OX=44689 GN=dst3 PE=3 SV=1 Length=562 Score = 221 bits (563), Expect = 2e-60, Method: Composition-based stats. Identities = 67/273 (25%), Positives = 114/273 (42%), Gaps = 28/273 (10%) Query 903 LGEGHFGKVSLYCY---DPTNDGTGEMVAVKALKADCGPQHRS-GWKQEIDILRT-LYHE 957 +G G FG V + ++A K ++ + + +EIDIL+ + Sbjct 29 VGSGSFGTVCACRWMKKKDRESNGNRLIACKFVEVNADDVETNLNLVKEIDILKESMDCP 88 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLH 1015 +I++YKGC L +VMEY GSL D + + ++ + +G+ YLH Sbjct 89 YIVEYKGCYLKSS--MLLIVMEYCKGGSLLDIIELCGKRLIEEEIAAVCAGVVKGLVYLH 146 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 ++ HRD+ A NVLLD + L K+ DFG++ +G + V +W APE + Sbjct 147 SKRTTHRDIKAGNVLLDEEGLPKLADFGVSTIAEQGQKMNTV----IGSPYWMAPEIIMG 202 Query 1076 YKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 + +D+WS G+T E+ PP++ + I + L Sbjct 203 QGYDQKADIWSLGITAIEIAELVPPRFDVPPSRVIFTIPH--------------QPPPSL 248 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P E +K C + RP+ + L+ Sbjct 249 KIPSDWSPEFNDFVKQCLSMNPALRPSAQQLLS 281 Score = 182 bits (463), Expect = 2e-47, Method: Composition-based stats. Identities = 61/313 (19%), Positives = 102/313 (33%), Gaps = 38/313 (12%) Query 569 ASPRTLNLSQLSFHRVDQKEITQL-SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 S NL + D + I Q+ +G G+ V R + Sbjct 2 NSDSVENLFISRISKDDPEAIFQIVEVVGSGSFGTVCACRWMKK---------------- 45 Query 628 VPGRDRGQELRVVLK--VLDPSHHDIALAFYETASLMS-QVSHTHLAFVHGVCVRGPENI 684 R+ + K ++ + L + ++ + ++ G ++ + Sbjct 46 -KDRESNGNRLIACKFVEVNADDVETNLNLVKEIDILKESMDCPYIVEYKGCYLKSSMLL 104 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 +V EY + G L + + V + L YL +K H ++ N+LL Sbjct 105 IVMEYCKGGSLLDIIELCGKRLIEEEIAAVCAGVVKGLVYLHSKRTTHRDIKAGNVLLDE 164 Query 745 LGLAEGTSPFIKLSDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 GL KL+D GV + W+APE + G D W G Sbjct 165 EGLP-------KLADFGVSTIAEQGQKMNTVIGSPYWMAPEIIMG--QGYDQKADIWSLG 215 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQH----RLPEPSCPQLATLTSQCLTYEPTQRP 857 T +EI P PS Q ++P P+ QCL+ P RP Sbjct 216 ITAIEIAEL-VPPRFDVPPSRVIFTIPHQPPPSLKIPSDWSPEFNDFVKQCLSMNPALRP 274 Query 858 SFRTILRDLTRLQ 870 S + +L L+ Sbjct 275 SAQQLLSHPFILK 287 >sp|Q5I6M2|HOG1_EXSTU Mitogen-activated protein kinase HOG1 OS=Exserohilum turcicum OX=93612 GN=HOG1 PE=2 SV=2 Length=329 Score = 214 bits (544), Expect = 2e-60, Method: Composition-based stats. Identities = 67/272 (25%), Positives = 105/272 (39%), Gaps = 29/272 (11%) Query 905 EGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYK 963 G FG V + T + VAVK + K P +E+ +L+ L HE+II Sbjct 1 MGAFGLVC----SAKDQLTNQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENIISLS 56 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRD 1023 E + V E + L L + + F QI G+ Y+H+ +HRD Sbjct 57 DIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYIHSAGVVHRD 114 Query 1024 LAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKFYYAS 1082 L N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 115 LKPSNILVNENCDLKICDFGLARIQDPQVTGY------VSTRYYRAPEIMLTWQKYDVEV 168 Query 1083 DVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTELLER 1130 D+WS G E+L + + EL+G + LR + L + Sbjct 169 DIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVQPLPK 228 Query 1131 GERLP---RPDKCPCEVYHLMKNCWETEASFR 1159 ER P + E L++N + R Sbjct 229 RERQPLANKFKNAEPEAVDLLENMLVFDPRKR 260 Score = 132 bits (333), Expect = 2e-32, Method: Composition-based stats. Identities = 33/210 (16%), Positives = 71/210 (34%), Gaps = 16/210 (8%) Query 621 MDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYETASLMSQVSHTHLAFVHGVCV 678 M + +D+ V +K ++ P ++ Y L+ + H ++ + + + Sbjct 1 MGAFGLVCSAKDQLTNQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENIISLSDIFI 60 Query 679 RG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCG 737 + VTE + L L + + Q+ L Y+ + +VH ++ Sbjct 61 SPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLYQILRGLKYIHSAGVVHRDLKP 117 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVERIPWLAPECLPGGANSLSTAMD 796 NIL+ + +K+ D G+ V + APE + +D Sbjct 118 SNILVNE-------NCDLKICDFGLARIQDPQVTGYVSTRYYRAPE-IMLTWQKYDVEVD 169 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 W G E+ +G+ + + Sbjct 170 IWSAGCIFAEML-EGKPLFPGKDHVNQFSI 198 >sp|Q9R0A5|NEK3_MOUSE Serine/threonine-protein kinase Nek3 OS=Mus musculus OX=10090 GN=Nek3 PE=1 SV=2 Length=511 Score = 219 bits (559), Expect = 2e-60, Method: Composition-based stats. Identities = 66/267 (25%), Positives = 115/267 (43%), Gaps = 29/267 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FG+ L + + + A+K ++ S ++E +L + H +I+ + Sbjct 10 IGQGSFGRALLV----LQESSNQTFAMKEIRLLKSDTQTS--RKEAVLLAKMKHPNIVAF 63 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQHY 1019 K E E L +VMEY G L + + +L + QIC G+ ++H + Sbjct 64 KESFE--AEGYLYIVMEYCDGGDLMQRIKQQKGKLFPEDTILNWFIQICLGVNHIHKRRV 121 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRD+ ++NV L ++ VK+GDFG A+ + + ++ PE + + Sbjct 122 LHRDIKSKNVFLTHNGKVKLGDFGSARLLSSPMAFACT---YVGTPYYVPPEIWENLPYN 178 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SD+WS G LYEL Q+ K L L + +G P P Sbjct 179 NKSDIWSLGCILYELCALKHPFQANSWKNLIL---------------KICQGPIHPLPAL 223 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLI 1166 C++ L+K + S RP+ L+ Sbjct 224 YSCKLQGLVKQMLKRNPSHRPSATTLL 250 Score = 162 bits (410), Expect = 5e-41, Method: Composition-based stats. Identities = 50/285 (18%), Positives = 94/285 (33%), Gaps = 40/285 (14%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 T L +GQG+ + +K + Sbjct 1 MDNYTVLRVIGQGSFGR------------------------ALLVLQESSNQTFAMKEIR 36 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 D + + A L++++ H ++ +V EY + G L +++++G Sbjct 37 LLKSDTQTS-RKEAVLLAKMKHPNIVAFKESFEAEGYLYIVMEYCDGGDLMQRIKQQKGK 95 Query 706 V-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + P + Q+ ++++ + ++H ++ +N+ L G +KL D G Sbjct 96 LFPEDTILNWFIQICLGVNHIHKRRVLHRDIKSKNVFLTHNG-------KVKLGDFGSAR 148 Query 765 GALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 S V ++ PE + D W G L E+C + Sbjct 149 LLSSPMAFACTYVGTPYYVPPEIWEN--LPYNNKSDIWSLGCILYELCALKHPFQANSWK 206 Query 821 SEKEHFYQR-QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + Q H LP +L L Q L P+ RPS T+L Sbjct 207 NLILKICQGPIHPLPALYSCKLQGLVKQMLKRNPSHRPSATTLLC 251 >sp|Q55A55|Y9848_DICDI Probable serine/threonine-protein kinase DDB_G0272092 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0272092 PE=2 SV=1 Length=986 Score = 229 bits (583), Expect = 2e-60, Method: Composition-based stats. Identities = 68/294 (23%), Positives = 113/294 (38%), Gaps = 19/294 (6%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 V ++ L LG G GKV + G+ VA+K LK+ + + +K+E Sbjct 594 WVIDEKTLTYNVLLGTGASGKVYKGTF------NGQEVAIKVLKSFTDKKDIAEFKKEFQ 647 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQI 1007 I+ L ++ + G + L +VMEY GSL L + Q Sbjct 648 IVSALRAPGVVYFHGA---GIKDKLCIVMEYCSRGSLYHILKDDTTQFTWDNFFNLGTQA 704 Query 1008 CEGMAYLHA--QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 + LH +HRDL + N+L+ + VKI DFGL++ + Sbjct 705 INSLDSLHNWTPQVLHRDLKSLNLLVTENWTVKICDFGLSRF--DTGSNLETLGKLRGTY 762 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 + APE K+ SDV+S G+ L+E+ C T L + L Sbjct 763 AYVAPEVYFGKKYTTKSDVYSMGIILWEMTYRCIKG----THLLPYAEYPHLKFDYQILI 818 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 ++ R P+ P + +L+ +++ RPT L + ++Y Sbjct 819 SSAKKDVRPTTPENAPESLKNLIARTLVKDSTLRPTTLEFYEELLKIRDEYNAN 872 Score = 159 bits (401), Expect = 4e-38, Method: Composition-based stats. Identities = 57/316 (18%), Positives = 105/316 (33%), Gaps = 56/316 (18%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 +D+K +T LG G VY+G GQE Sbjct 590 DSDSWVIDEKTLTYNVLLGTGASGKVYKG------------------------TFNGQE- 624 Query 638 RVVLKVLDP-SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 V +KVL + F + ++S + + + HG ++ + +V EY G L Sbjct 625 -VAIKVLKSFTDKKDIAEFKKEFQIVSALRAPGVVYFHGAGIK-DKLCIVMEYCSRGSLY 682 Query 697 VWLRRERGHVPMAWKMVVAQQLASALSYLEN--KNLVHGNVCGRNILLARLGLAEGTSPF 754 L+ + + Q ++L L N ++H ++ N+L+ + Sbjct 683 HILKDDTTQFTWDNFFNLGTQAINSLDSLHNWTPQVLHRDLKSLNLLVTE-------NWT 735 Query 755 IKLSDPGVGLGALSRE-----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 +K+ D G+ + ++APE G +T D + G L E+ + Sbjct 736 VKICDFGLSRFDTGSNLETLGKLRGTYAYVAPEVYFG--KKYTTKSDVYSMGIILWEMTY 793 Query 810 DGEAPLQSRSPSEKEHFYQRQHRL------------PEPSCPQLATLTSQCLTYEPTQRP 857 +E H L PE + L L ++ L + T RP Sbjct 794 RCIKGTHLLPYAEYPHLKFDYQILISSAKKDVRPTTPENAPESLKNLIARTLVKDSTLRP 853 Query 858 SFRTILRDLTRLQPHN 873 + +L +++ Sbjct 854 TTLEFYEELLKIRDEY 869 >sp|Q15569|TESK1_HUMAN Dual specificity testis-specific protein kinase 1 OS=Homo sapiens OX=9606 GN=TESK1 PE=1 SV=2 Length=626 Score = 223 bits (567), Expect = 2e-60, Method: Composition-based stats. Identities = 73/290 (25%), Positives = 122/290 (42%), Gaps = 28/290 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +G G F +V Y + +G+++ LK + P +R +E+ ++ L H Sbjct 57 FHCAEKIGAGFFSEV----YKVRHRQSGQVM---VLKMNKLPSNRGNTLREVQLMNRLRH 109 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLH 1015 +I+++ G C QG+ L + EY+ G+L L + L A I G+ YLH Sbjct 110 PNILRFMGVCVHQGQ--LHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIARGLRYLH 167 Query 1016 AQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVRE-DGDSPVFWYAPE 1071 ++ HRDL ++N L+ D +GDFGLA+ +P E R +W APE Sbjct 168 SKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPE 227 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 L+ + +DV++FG+ L EL+ + + + T++ Sbjct 228 VLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVG-------- 279 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 D CP L +C E S R F + L+ + E+ AP Sbjct 280 ------DDCPLPFLLLAIHCCNLEPSTRAPFTEITQHLEWILEQLPEPAP 323 Score = 194 bits (492), Expect = 9e-51, Method: Composition-based stats. Identities = 70/311 (23%), Positives = 111/311 (36%), Gaps = 45/311 (14%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 +S R L + S RVD + +G G + VY+ R Sbjct 39 SSYRALRSAVSSLARVD--DFHCAEKIGAGFFSEVYKVRH-------------------- 76 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 R GQ + + + L + + LM+++ H ++ GVCV + +TE Sbjct 77 --RQSGQVMVLKMNKLPSNRGNT----LREVQLMNRLRHPNILRFMGVCVHQGQLHALTE 130 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 Y+ G L+ L + ++ +A +A L YL +K + H ++ +N L+ R Sbjct 131 YMNGGTLEQLLSSPE-PLSWPVRLHLALDIARGLRYLHSKGVFHRDLTSKNCLVRR---- 185 Query 749 EGTSPFIKLSDPGVG-LGALSREER-------VERIPWLAPECLPGGANSLSTAMDKWGF 800 E + D G+ + RE V W+APE L G D + F Sbjct 186 EDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGEL--YDEKADVFAF 243 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-LPEPSCP-QLATLTSQCLTYEPTQRPS 858 G L E+ A +E R L CP L C EP+ R Sbjct 244 GIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGDDCPLPFLLLAIHCCNLEPSTRAP 303 Query 859 FRTILRDLTRL 869 F I + L + Sbjct 304 FTEITQHLEWI 314 >sp|Q7YQL3|PAK3_PONPY Serine/threonine-protein kinase PAK 3 OS=Pongo pygmaeus OX=9600 GN=PAK3 PE=2 SV=1 Length=559 Score = 221 bits (562), Expect = 2e-60, Method: Composition-based stats. Identities = 66/318 (21%), Positives = 120/318 (38%), Gaps = 23/318 (7%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 T + + T+ R+ R + + + + K+ + +G+G G Sbjct 236 TPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASG 295 Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 V Y + TG+ VA+K + P+ + EI ++R + +I+ Y Sbjct 296 TV----YTALDIATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVG 350 Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029 E L +VMEY+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+ Sbjct 351 DE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNI 408 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 LL D VK+ DFG + R +W APE + + D+WS G+ Sbjct 409 LLGMDGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGI 465 Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149 E++ PP + T L P++ + Sbjct 466 MAIEMV-----EGEPPYLNENPLRALYLIATNGT--------PELQNPERLSAVFRDFLN 512 Query 1150 NCWETEASFRPTFENLIP 1167 C E + R + + L+ Sbjct 513 RCLEMDVDRRGSAKELLQ 530 Score = 178 bits (451), Expect = 6e-46, Method: Composition-based stats. Identities = 54/291 (19%), Positives = 97/291 (33%), Gaps = 44/291 (15%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +K+ T+ +GQG VY D V +K + Sbjct 279 PKKKYTRFEKIGQGASGTVY------------------------TALDIATGQEVAIKQM 314 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + +M + + ++ + G E +V EY+ G L + Sbjct 315 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 372 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + V ++ AL +L + ++H ++ NILL G +KL+D G Sbjct 373 CMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 425 Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 R V W+APE + A +D W G +E+ +GE P + +P Sbjct 426 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENP 482 Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + PE ++CL + +R S + +L+ Sbjct 483 LRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPF 533 >sp|Q7YQL4|PAK3_PANTR Serine/threonine-protein kinase PAK 3 OS=Pan troglodytes OX=9598 GN=PAK3 PE=2 SV=1 Length=559 Score = 221 bits (562), Expect = 2e-60, Method: Composition-based stats. Identities = 66/318 (21%), Positives = 120/318 (38%), Gaps = 23/318 (7%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 T + + T+ R+ R + + + + K+ + +G+G G Sbjct 236 TPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASG 295 Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 V Y + TG+ VA+K + P+ + EI ++R + +I+ Y Sbjct 296 TV----YTALDIATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVG 350 Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029 E L +VMEY+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+ Sbjct 351 DE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNI 408 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 LL D VK+ DFG + R +W APE + + D+WS G+ Sbjct 409 LLGMDGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGI 465 Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149 E++ PP + T L P++ + Sbjct 466 MAIEMV-----EGEPPYLNENPLRALYLIATNGT--------PELQNPERLSAVFRDFLN 512 Query 1150 NCWETEASFRPTFENLIP 1167 C E + R + + L+ Sbjct 513 RCLEMDVDRRGSAKELLQ 530 Score = 178 bits (451), Expect = 6e-46, Method: Composition-based stats. Identities = 54/291 (19%), Positives = 97/291 (33%), Gaps = 44/291 (15%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +K+ T+ +GQG VY D V +K + Sbjct 279 PKKKYTRFEKIGQGASGTVY------------------------TALDIATGQEVAIKQM 314 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + +M + + ++ + G E +V EY+ G L + Sbjct 315 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 372 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + V ++ AL +L + ++H ++ NILL G +KL+D G Sbjct 373 CMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 425 Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 R V W+APE + A +D W G +E+ +GE P + +P Sbjct 426 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENP 482 Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + PE ++CL + +R S + +L+ Sbjct 483 LRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPF 533 >sp|O75914|PAK3_HUMAN Serine/threonine-protein kinase PAK 3 OS=Homo sapiens OX=9606 GN=PAK3 PE=1 SV=2 Length=559 Score = 221 bits (562), Expect = 2e-60, Method: Composition-based stats. Identities = 66/318 (21%), Positives = 120/318 (38%), Gaps = 23/318 (7%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 T + + T+ R+ R + + + + K+ + +G+G G Sbjct 236 TPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASG 295 Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 V Y + TG+ VA+K + P+ + EI ++R + +I+ Y Sbjct 296 TV----YTALDIATGQEVAIKQMNLQQQPK-KELIINEILVMRENKNPNIVNYLDSYLVG 350 Query 970 GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNV 1029 E L +VMEY+ GSL D + + Q+ ++ + + +LH+ IHRD+ + N+ Sbjct 351 DE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNI 408 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 LL D VK+ DFG + R +W APE + + D+WS G+ Sbjct 409 LLGMDGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGI 465 Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK 1149 E++ PP + T L P++ + Sbjct 466 MAIEMV-----EGEPPYLNENPLRALYLIATNGT--------PELQNPERLSAVFRDFLN 512 Query 1150 NCWETEASFRPTFENLIP 1167 C E + R + + L+ Sbjct 513 RCLEMDVDRRGSAKELLQ 530 Score = 178 bits (451), Expect = 6e-46, Method: Composition-based stats. Identities = 54/291 (19%), Positives = 97/291 (33%), Gaps = 44/291 (15%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 +K+ T+ +GQG VY D V +K + Sbjct 279 PKKKYTRFEKIGQGASGTVY------------------------TALDIATGQEVAIKQM 314 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + +M + + ++ + G E +V EY+ G L + Sbjct 315 NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TET 372 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + V ++ AL +L + ++H ++ NILL G +KL+D G Sbjct 373 CMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCA 425 Query 765 GAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 R V W+APE + A +D W G +E+ +GE P + +P Sbjct 426 QITPEQSKRSTMVGTPYWMAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENP 482 Query 821 SEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + PE ++CL + +R S + +L+ Sbjct 483 LRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPF 533 >sp|Q6NQ87|CRK22_ARATH Cysteine-rich receptor-like protein kinase 22 OS=Arabidopsis thaliana OX=3702 GN=CRK22 PE=2 SV=1 Length=660 Score = 223 bits (569), Expect = 2e-60, Method: Composition-based stats. Identities = 77/335 (23%), Positives = 122/335 (36%), Gaps = 32/335 (10%) Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 C + QR F + +DV T N K LGEG Sbjct 316 CWRRKSLQRTEFES------------DSDVSTTNSLQYEFKTIEAATNKFSKSNKLGEGR 363 Query 908 FGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 FG+V + G VAVK L G Q ++ E ++ + H ++ + G C Sbjct 364 FGEVYKGKF-----SNGTEVAVKRLSKVSG-QDTKKFRNEAVLVSKIQHRNLARLLGFCL 417 Query 968 DQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQH---YI 1020 K L+ E+V SL +L + + + I +G+ +LH I Sbjct 418 QGDGK--FLIYEFVLNKSLDYFLFDPEKQGELDWTRRYKIIGGIAQGILHLHQDPQLTII 475 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 +RD A N+LLD D KI DFG+A ++ V + +PE KF Sbjct 476 YRDFKASNILLDADMNPKISDFGMATVFGMEESRGNTNWIAETFV-YMSPEYAVHGKFSM 534 Query 1081 ASDVWSFGVTLYELLTHCDSS----QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 SDV+SFG+ + E+++ +S T L+ A +LL+ Sbjct 535 KSDVYSFGILILEIISGKKNSSLYQNDETTTAGNLVTYAWRLWRNGSQLKLLDSSIGRNY 594 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 H+ C + RP ++ +L + Sbjct 595 QSNEVTRCIHIALLCVQENPEDRPKLSTIVSMLTS 629 Score = 206 bits (524), Expect = 1e-54, Method: Composition-based stats. Identities = 62/331 (19%), Positives = 108/331 (33%), Gaps = 69/331 (21%) Query 569 ASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 + T N Q F ++ + ++ + LG+G VY+G+ Sbjct 331 SDVSTTNSLQYEFKTIEAATNKFSKSNKLGEGRFGEVYKGK------------------- 371 Query 627 LVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMV 686 V +K L F A L+S++ H +LA + G C++G ++ Sbjct 372 ------FSNGTEVAVKRLSKVSGQDTKKFRNEAVLVSKIQHRNLARLLGFCLQGDGKFLI 425 Query 687 TEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENKN---LVHGNVCGRNIL 741 E+V + LD +L + W + + +A + +L +++ + NIL Sbjct 426 YEFVLNKSLDYFLFDPEKQGELDWTRRYKIIGGIAQGILHLHQDPQLTIIYRDFKASNIL 485 Query 742 LARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAPECLPGGANSLSTAM 795 L K+SD G+ E R E +++PE G S Sbjct 486 LD-------ADMNPKISDFGMATVFGMEESRGNTNWIAETFVYMSPEYAVHG--KFSMKS 536 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKE---HFYQRQHRLPEPSC-------------- 838 D + FG +LEI G+ E + RL Sbjct 537 DVYSFGILILEIIS-GKKNSSLYQNDETTTAGNLVTYAWRLWRNGSQLKLLDSSIGRNYQ 595 Query 839 ----PQLATLTSQCLTYEPTQRPSFRTILRD 865 + + C+ P RP TI+ Sbjct 596 SNEVTRCIHIALLCVQENPEDRPKLSTIVSM 626 >sp|Q940H6|SRK2E_ARATH Serine/threonine-protein kinase SRK2E OS=Arabidopsis thaliana OX=3702 GN=SRK2E PE=1 SV=1 Length=362 Score = 214 bits (546), Expect = 2e-60, Method: Composition-based stats. Identities = 72/285 (25%), Positives = 120/285 (42%), Gaps = 26/285 (9%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 P P + + ++D+G G+FG L + + E+VAVK + + G + Sbjct 9 PMDLPIMHDSDRYELVKDIGSGNFGVARLM----RDKQSNELVAVKYI--ERGEKIDENV 62 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLF 1003 K+EI R+L H +I+++K L +VMEY G L + + + F Sbjct 63 KREIINHRSLRHPNIVRFKEVILTPTH--LAIVMEYASGGELFERICNAGRFSEDEARFF 120 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDG 1061 QQ+ G++Y HA HRDL N LLD +KI DFG +K + + + Sbjct 121 FQQLISGVSYCHAMQVCHRDLKLENTLLDGSPAPRLKICDFGYSK---SSVLHSQPKSTV 177 Query 1062 DSPVFWYAPECLKEYKFYYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 +P + APE L + ++ DVWS GVTLY +L + P + + Sbjct 178 GTPA-YIAPEVLLKKEYDGKVADVWSCGVTLYVMLVGAYPFEDPE----------EPKNF 226 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + +L +P E HL+ + + + R + + Sbjct 227 RKTIHRILNVQYAIPDYVHISPECRHLISRIFVADPAKRISIPEI 271 Score = 160 bits (404), Expect = 2e-41, Method: Composition-based stats. Identities = 55/332 (17%), Positives = 98/332 (30%), Gaps = 47/332 (14%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 D + +G G RD+ V +K + Sbjct 17 DSDRYELVKDIGSGNFG------------------------VARLMRDKQSNELVAVKYI 52 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + I + H ++ V + +V EY G L + G Sbjct 53 ERG-EKIDENVKREIINHRSLRHPNIVRFKEVILTPTHLAIVMEYASGGELFERI-CNAG 110 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 QQL S +SY + H ++ N LL +P +K+ D G Sbjct 111 RFSEDEARFFFQQLISGVSYCHAMQVCHRDLKLENTLLD-----GSPAPRLKICDFGYSK 165 Query 765 GAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 ++ + V ++APE L D W G TL + G P + P Sbjct 166 SSVLHSQPKSTVGTPAYIAPEVLLKKEYD-GKVADVWSCGVTLYVMLV-GAYPFED--PE 221 Query 822 EKEHFYQRQHRL---------PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 E ++F + HR+ P+ L S+ +P +R S I L+ Sbjct 222 EPKNFRKTIHRILNVQYAIPDYVHISPECRHLISRIFVADPAKRISIPEIRNHEWFLKNL 281 Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 + + + + + ++ + Sbjct 282 PADLMNDNTMTTQFDESDQPGQSIEEIMQIIA 313 >sp|Q6PHR2|ULK3_HUMAN Serine/threonine-protein kinase ULK3 OS=Homo sapiens OX=9606 GN=ULK3 PE=1 SV=2 Length=472 Score = 218 bits (555), Expect = 2e-60, Method: Composition-based stats. Identities = 67/280 (24%), Positives = 112/280 (40%), Gaps = 26/280 (9%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQE 947 LG G + V T E+VA+K + K E Sbjct 6 WGPPRLDGFILTERLGSGTYATVYKAYAK---KDTREVVAIKCVAKKSLNKASVENLLTE 62 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQ 1006 I+IL+ + H HI++ K D ++ L+ME+ G L ++ R + +F QQ Sbjct 63 IEILKGIRHPHIVQLKDFQWDSD--NIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ 120 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLD--NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 + + +LH ++ H DL +N+LL +K+ DFG A+ + E + +R Sbjct 121 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLR----GS 176 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 + APE + + ++ D+WS GV LYE L S LE +R Sbjct 177 PLYMAPEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELE---------EKIRS 227 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 ++E R C L++ E + S R +F++ Sbjct 228 NRVIELPLRPLLSRDC----RDLLQRLLERDPSRRISFQD 263 Score = 191 bits (486), Expect = 4e-51, Method: Composition-based stats. Identities = 66/293 (23%), Positives = 106/293 (36%), Gaps = 37/293 (13%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 LG GT VY+ + + V K L+ + Sbjct 14 FILTERLGSGTYATVYKAYAKKDTREVVAIKC------------------VAKKSLNKAS 55 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 + ++ + H H+ + ++ E+ G L ++ R +P Sbjct 56 VEN---LLTEIEILKGIRHPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRI-LPE 111 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 V QQLASAL +L +N+ H ++ +NILL+ L P +KL+D G Sbjct 112 KVARVFMQQLASALQFLHERNISHLDLKPQNILLSSL-----EKPHLKLADFGFAQHMSP 166 Query 769 -REERV--ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 E+ V ++APE + +D W G L E F G+ P SRS SE E Sbjct 167 WDEKHVLRGSPLYMAPEMV--CQRQYDARVDLWSMGVILYEALF-GQPPFASRSFSELEE 223 Query 826 FYQRQHRLPEPSCPQLA----TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 + + P P L+ L + L +P++R SF+ H Sbjct 224 KIRSNRVIELPLRPLLSRDCRDLLQRLLERDPSRRISFQDFFAHPWVDLEHMP 276 >sp|Q84VQ3|CIPKQ_ARATH CBL-interacting serine/threonine-protein kinase 26 OS=Arabidopsis thaliana OX=3702 GN=CIPK26 PE=1 SV=2 Length=439 Score = 217 bits (552), Expect = 2e-60, Method: Composition-based stats. Identities = 61/269 (23%), Positives = 111/269 (41%), Gaps = 27/269 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTLYHEHI 959 LG+G F KV N TGE VA+K L + +H+ ++EI ++ + H ++ Sbjct 18 TLGQGTFAKVRC----AVNTETGERVALKILDKEKVLKHKMAEQIRREICTMKLINHPNV 73 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ + + + +V+E+ G L D + + + QQ+ + Y H++ Sbjct 74 VRLYEVLASKTK--IYIVLEFGTGGELFDKIVHDGRLKEENARKYFQQLINAVDYCHSRG 131 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N+LLD +K+ DFGL+ + + +P + APE L + + Sbjct 132 VYHRDLKPENLLLDAQGNLKVSDFGLSALSRQVRGDGLLHTACGTPN-YAAPEVLNDQGY 190 Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 A +D+WS GV L+ LL + ++ L + + GE P Sbjct 191 DGATADLWSCGVILFVLLAGYLPFED---------------SNLMTLYKKIIAGE-YHCP 234 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 +L+ + R T ++ Sbjct 235 PWLSPGAKNLIVRILDPNPMTRITIPEVL 263 Score = 166 bits (419), Expect = 9e-43, Method: Composition-based stats. Identities = 54/296 (18%), Positives = 91/296 (31%), Gaps = 42/296 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + LGQGT V + RV LK+LD Sbjct 12 KYEVGKTLGQGTFAKV------------------------RCAVNTETGERVALKILDKE 47 Query 648 H---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 H +A M ++H ++ ++ V + +V E+ G L + G Sbjct 48 KVLKHKMAEQIRREICTMKLINHPNVVRLYEVLASKTKIYIVLEFGTGGELFDKI-VHDG 106 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763 + QQL +A+ Y ++ + H ++ N+LL G +K+SD G+ Sbjct 107 RLKEENARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDAQG-------NLKVSDFGLSA 159 Query 764 -----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 G + APE L D W G L + S Sbjct 160 LSRQVRGDGLLHTACGTPNYAAPEVLNDQGYD-GATADLWSCGVILFVLLAGYLPFEDSN 218 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 + + ++ P P L + L P R + +L D + + Sbjct 219 LMTLYKKIIAGEYHCPPWLSPGAKNLIVRILDPNPMTRITIPEVLGDAWFKKNYKP 274 >sp|Q6ERS4|CIPKG_ORYSJ CBL-interacting protein kinase 16 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK16 PE=2 SV=1 Length=456 Score = 217 bits (553), Expect = 3e-60, Method: Composition-based stats. Identities = 63/271 (23%), Positives = 110/271 (41%), Gaps = 29/271 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA---DCGPQHRSGWKQEIDILRTLYHEHI 959 LG+G F KV + +GE VA+K + ++EI I+R + H ++ Sbjct 28 LGQGTFAKVYYG----RDLRSGESVAIKVIDKARLRRTEGMVEQLRREISIMRMVRHPNV 83 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + + + + +VMEY G L + R + + QQ+ + + H + Sbjct 84 VGIREVLASRA--RVFVVMEYARGGELFAKVARGRLTEEHARRYFQQLVAAVGFCHGRGV 141 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 HRDL N+LLD + +K+ DFGLA + + + +P + APE L++ + Sbjct 142 AHRDLKPENLLLDEEGRLKVTDFGLAALPEQLRQDGLLHTQCGTPA-YVAPEVLRKRGYD 200 Query 1080 YA-SDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 A +D+WS GV LY LL Q K + I A+ Q+ P Sbjct 201 GARADLWSCGVVLYVLLCGFLPFQHENYAKMYQKIFKAEYQV-----------------P 243 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 + L+ + + R + ++ Sbjct 244 PWVSGDARRLIVRLLVVDPAKRISIPEIMRT 274 Score = 169 bits (428), Expect = 9e-44, Method: Composition-based stats. Identities = 54/289 (19%), Positives = 93/289 (32%), Gaps = 44/289 (15%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647 LGQGT VY G RD V +KV+D + Sbjct 23 ELGRLLGQGTFAKVYYG------------------------RDLRSGESVAIKVIDKARL 58 Query 648 --HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + S+M V H ++ + V +V EY G L + + RG Sbjct 59 RRTEGMVEQLRREISIMRMVRHPNVVGIREVLASRARVFVVMEYARGGEL--FAKVARGR 116 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763 + QQL +A+ + + + H ++ N+LL G +K++D G+ Sbjct 117 LTEEHARRYFQQLVAAVGFCHGRGVAHRDLKPENLLLDEEGR-------LKVTDFGLAAL 169 Query 764 ----LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + ++APE L D W G L + Sbjct 170 PEQLRQDGLLHTQCGTPAYVAPEVLRKRGYD-GARADLWSCGVVLYVLLCGFLPFQHENY 228 Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + ++ ++++P L + L +P +R S I+R Sbjct 229 AKMYQKIFKAEYQVPPWVSGDARRLIVRLLVVDPAKRISIPEIMRTPWF 277 >sp|Q8SRF5|Y823_ENCCU Probable cell division protein kinase ECU08_0230 OS=Encephalitozoon cuniculi (strain GB-M1) OX=284813 GN=ECU08_0230 PE=3 SV=1 Length=265 Score = 211 bits (536), Expect = 3e-60, Method: Composition-based stats. Identities = 66/270 (24%), Positives = 127/270 (47%), Gaps = 20/270 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G +G+V Y+ + T E VA+K ++ + +EI IL+ L H +II Sbjct 10 IGSGTYGEV----YEAIDTETKEKVALKRIRLNEKEGMPGTALREISILKKLSHRNIISL 65 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHR 1022 + L +V ++ L+ Y+ ++ ++ Q+ G+ YLH + +HR Sbjct 66 VSII--HTDALLTMVFPFIDY-ELKKYIGMNTGK--NIMELVNQLICGVHYLHRMNVVHR 120 Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFYYA 1081 DL +N+L+ +D ++KI DFGL++++ Y +++ +PE L + + Sbjct 121 DLKPQNILVTSDGVLKIADFGLSRSLEIRVPPYSSE---VVTLWYRSPELLMGSTSYRFY 177 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 D+WS G +YE++T + +K +L I + T L ++E+ RL P Sbjct 178 VDIWSLGCIIYEMIT-LEPLFPGESKENQLTLIRRKAGTRRSLRGMVEQ--RLAVPKF-- 232 Query 1142 CEVYHLMKNCWETEASFRPTFENLIPILKT 1171 V ++ C + + R T + ++ IL+ Sbjct 233 --VTEIIVRCLDFNYNQRITADEIMEILEN 260 Score = 147 bits (372), Expect = 3e-38, Method: Composition-based stats. Identities = 51/288 (18%), Positives = 100/288 (35%), Gaps = 51/288 (18%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 + +G GT VYE D + +V LK + + Sbjct 5 ILGALIGSGTYGEVYEAI------------------------DTETKEKVALKRIRLNEK 40 Query 650 DIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 + S++ ++SH ++ + + MV ++++ L ++ G Sbjct 41 EGMPGTALREISILKKLSHRNIISLVSIIHTDALLTMVFPFIDY-ELKKYIGMNTGKN-- 97 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 M + QL + YL N+VH ++ +NIL+ G+ +K++D G+ Sbjct 98 --IMELVNQLICGVHYLHRMNVVHRDLKPQNILVTSDGV-------LKIADFGLSRSLEI 148 Query 769 R----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE-APLQSRSPSEK 823 R V + + +PE L G+ S +D W G + E+ P +S+ Sbjct 149 RVPPYSSEVVTLWYRSPELLM-GSTSYRFYVDIWSLGCIIYEMITLEPLFPGESKENQLT 207 Query 824 EHFYQRQHRLPEP--------SCPQLATLTSQCLTYEPTQRPSFRTIL 863 + R + + +CL + QR + I+ Sbjct 208 LIRRKAGTRRSLRGMVEQRLAVPKFVTEIIVRCLDFNYNQRITADEIM 255 >sp|O74536|SNF1_SCHPO SNF1-like protein kinase ssp2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ssp2 PE=1 SV=1 Length=576 Score = 221 bits (562), Expect = 3e-60, Method: Composition-based stats. Identities = 72/278 (26%), Positives = 112/278 (40%), Gaps = 31/278 (11%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK--QEID 949 H LGEG FGKV L T+ T + VA+K + + + +EI Sbjct 29 RHIGPYIIRETLGEGSFGKVKL----ATHYKTQQKVALKFISRQLLKKSDMHMRVEREIS 84 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQIC 1008 L+ L H HIIK + + +V+EY G L DY+ + + + F QQI Sbjct 85 YLKLLRHPHIIKLYDVITTPTD--IVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQII 141 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 + Y H +HRDL N+LLD++ VKI DFGL+ + +G+ ++ SP + Sbjct 142 CAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGN---FLKTSCGSPN-YA 197 Query 1069 APECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + + DVWS G+ LY +L L ++ Sbjct 198 APEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPFDDEFIPNL-----------FKKVNSC 246 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + PD L++ + R T + + Sbjct 247 V-----YVMPDFLSPGAQSLIRRMIVADPMQRITIQEI 279 Score = 177 bits (448), Expect = 2e-45, Method: Composition-based stats. Identities = 58/322 (18%), Positives = 108/322 (34%), Gaps = 43/322 (13%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 QP E +L+ R R L +S + I LG+G+ V Sbjct 1 MQPQEV-DLMENSTMRNGARVLPPEAISKRHIGPYIIR--ETLGEGSFGKV--------- 48 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTH 669 + +V LK + D+ + S + + H H Sbjct 49 ---------------KLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPH 93 Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729 + ++ V + +MV EY G L ++ E+ + QQ+ A+ Y Sbjct 94 IIKLYDVITTPTDIVMVIEYA-GGELFDYI-VEKKRMTEDEGRRFFQQIICAIEYCHRHK 151 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR---EERVERIPWLAPECLPG 786 +VH ++ N+LL + +K++D G+ + + APE + G Sbjct 152 IVHRDLKPENLLLD-------DNLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVING 204 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTS 846 + +D W G L + P+ + + +P+ P +L Sbjct 205 KLYA-GPEVDVWSCGIVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQSLIR 263 Query 847 QCLTYEPTQRPSFRTILRDLTR 868 + + +P QR + + I RD Sbjct 264 RMIVADPMQRITIQEIRRDPWF 285 >sp|Q55E58|PATS1_DICDI Probable serine/threonine-protein kinase pats1 OS=Dictyostelium discoideum OX=44689 GN=pats1 PE=3 SV=1 Length=3184 Score = 231 bits (590), Expect = 3e-60, Method: Composition-based stats. Identities = 84/294 (29%), Positives = 126/294 (43%), Gaps = 52/294 (18%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG------------PQHRSGWKQEIDI 950 +GEG V + G+ VAVK LK + + +++E + Sbjct 2253 IGEGGAALVYRARWQ------GQTVAVKKLKTIENLDSPIEINDISLSKAFNEFRRECWV 2306 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQIC 1008 + L H +I++ KG C D L +V EY+P G+L +L + L A I Sbjct 2307 MSELEHPNIVQLKGLCLD----PLCIVTEYLPHGNLYSFLHKPEMEFSWLFRLKVALDIS 2362 Query 1009 EGMAYLHAQ--HYIHRDLAARNVLL-----DNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 GMA+LH+ IHRDL + N+LL + + K+ DFGL+ + + G Sbjct 2363 SGMAFLHSSTPPIIHRDLKSPNILLASINENAQTIAKVVDFGLS------GLQHTITNRG 2416 Query 1062 DSPVFWYAPECL-KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 W APE L K + +DV++FGV L+EL+T D L Sbjct 2417 VENPLWLAPEILNKTKEASTQTDVYAFGVILWELVTRKDYFGEIGFMTL----------- 2465 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + E + GER P+ CP L+ CW+T+AS RP F + L + E Sbjct 2466 ---IEEKVINGERPKIPEDCPEMYSKLIVECWQTDASQRPKFSEIEDRLIKIAE 2516 Score = 220 bits (560), Expect = 1e-56, Method: Composition-based stats. Identities = 67/316 (21%), Positives = 130/316 (41%), Gaps = 23/316 (7%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L +S + ++ ++ +G+G VY R + + + +++ D Sbjct 2231 DLVMSNFTGAKIPFDQLMIEELIGEGGAALVYRARWQGQTVAVKKLKTIENLDSP----- 2285 Query 633 RGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEH 692 +++ D S F +MS++ H ++ + G+C+ +VTEY+ H Sbjct 2286 --------IEINDISLSKAFNEFRRECWVMSELEHPNIVQLKGLCLD--PLCIVTEYLPH 2335 Query 693 GPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK--NLVHGNVCGRNILLARLGLAEG 750 G L +L + +++ VA ++S +++L + ++H ++ NILLA + E Sbjct 2336 GNLYSFLHKPEMEFSWLFRLKVALDISSGMAFLHSSTPPIIHRDLKSPNILLASIN--EN 2393 Query 751 TSPFIKLSDPGV-GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICF 809 K+ D G+ GL VE WLAPE + ST D + FG L E+ Sbjct 2394 AQTIAKVVDFGLSGLQHTITNRGVENPLWLAPE-ILNKTKEASTQTDVYAFGVILWELVT 2452 Query 810 DGEAP--LQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + + + E++ + ++PE + L +C + +QRP F I L Sbjct 2453 RKDYFGEIGFMTLIEEKVINGERPKIPEDCPEMYSKLIVECWQTDASQRPKFSEIEDRLI 2512 Query 868 RLQPHNLADVLTVNPD 883 ++ D+ N Sbjct 2513 KIAEAMFPDIHLSNIY 2528 >sp|Q8IU85|KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D OS=Homo sapiens OX=9606 GN=CAMK1D PE=1 SV=1 Length=385 Score = 215 bits (547), Expect = 3e-60, Method: Composition-based stats. Identities = 68/269 (25%), Positives = 101/269 (38%), Gaps = 30/269 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG G F +V L TG++ AVK + S + EI +LR + HE+I+ Sbjct 28 TLGTGAFSEVVL----AEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVA 83 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHYI 1020 + E L LVM+ V G L D + +Q+ + + YLH + Sbjct 84 LEDIYESPNH--LYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141 Query 1021 HRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 HRDL N+L D + + I DFGL+K +G V + APE L + Sbjct 142 HRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGD----VMSTACGTPGYVAPEVLAQKP 197 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + A D WS GV Y LL + ++L+ P Sbjct 198 YSKAVDCWSIGVIAYILLCGYPPF--------------YDENDSKLFEQILKAEYEFDSP 243 Query 1138 --DKCPCEVYHLMKNCWETEASFRPTFEN 1164 D ++N E + + R T E Sbjct 244 YWDDISDSAKDFIRNLMEKDPNKRYTCEQ 272 Score = 148 bits (373), Expect = 3e-37, Method: Composition-based stats. Identities = 43/314 (14%), Positives = 89/314 (28%), Gaps = 45/314 (14%) Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 + R S + ++ LG G + V Sbjct 1 MARENGESSSSWKKQAEDIKKI----FEFKETLGTGAFSEV------------------- 37 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGP 681 V ++ +K + + +++ ++ H ++ + + Sbjct 38 -----VLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPN 92 Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNIL 741 +V + V G L + E+G + +Q+ A+ YL +VH ++ N+L Sbjct 93 HLYLVMQLVSGGELFDRI-VEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLL 151 Query 742 LARLGLAEGTSPFIKLSDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKW 798 ++ I +SD G+ ++APE L S A+D W Sbjct 152 ----YYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQ--KPYSKAVDCW 205 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQR-----QHRLPEPSCPQLATLTSQCLTYEP 853 G I G P + S+ + + + +P Sbjct 206 SIGVIAY-ILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264 Query 854 TQRPSFRTILRDLT 867 +R + R Sbjct 265 NKRYTCEQAARHPW 278 >sp|Q5MAI5|CDKL4_HUMAN Cyclin-dependent kinase-like 4 OS=Homo sapiens OX=9606 GN=CDKL4 PE=2 SV=2 Length=379 Score = 215 bits (547), Expect = 3e-60, Method: Composition-based stats. Identities = 67/295 (23%), Positives = 122/295 (41%), Gaps = 34/295 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960 GEG +G V + N +G++VAVK ++++ P + +EI +L+ L H +++ Sbjct 9 KTGEGSYGVV----FKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPNLV 64 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ--LLLFAQQICEGMAYLHAQH 1018 + + + LV EY +L + L R+ G+A + Q + + + H + Sbjct 65 NLIEVFRRK--RKMHLVFEYCDH-TLLNELERNPNGVADGVIKSVLWQTLQALNFCHIHN 121 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEYK 1077 IHRD+ N+L+ ++KI DFG A+ + G Y D + ++ APE L + + Sbjct 122 CIHRDIKPENILITKQGIIKICDFGFAQILIPGDAY----TDYVATRWYRAPELLVGDTQ 177 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE-----RGE 1132 + + D+W+ G ELLT + I + R + + G Sbjct 178 YGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNGFFHGI 237 Query 1133 RLPRPDKC-----------PCEVYHLMKNCWETEASFRPTFENLIP--ILKTVHE 1174 +P P+ P + + MK C + R T L+ + E Sbjct 238 SIPEPEDMETLEEKFSDVHPVAL-NFMKGCLKMNPDDRLTCSQLLESSYFDSFQE 291 Score = 157 bits (396), Expect = 3e-40, Method: Composition-based stats. Identities = 51/260 (20%), Positives = 93/260 (36%), Gaps = 41/260 (16%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ +L+ G+G+ V++ R + G V +K Sbjct 1 MEKYEKLAKTGEGSYGVVFKCRNKTSGQ------------------------VVAVKKFV 36 Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 S D + ++ Q+ H +L + V R + +V EY +H L L R Sbjct 37 ESEDDPVVKKIALREIRMLKQLKHPNLVNLIEVFRRKRKMHLVFEYCDH-TLLNELERNP 95 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 V V Q AL++ N +H ++ NIL+ + G+ IK+ D G Sbjct 96 NGVADGVIKSVLWQTLQALNFCHIHNCIHRDIKPENILITKQGI-------IKICDFGFA 148 Query 764 ---LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 + + + V + APE L G +++D W G E+ G+ +S Sbjct 149 QILIPGDAYTDYVATRWYRAPELLV-GDTQYGSSVDIWAIGCVFAELL-TGQPLWPGKSD 206 Query 821 SEKEHFYQR--QHRLPEPSC 838 ++ + R +P Sbjct 207 VDQLYLIIRTLGKLIPRHQS 226 >sp|Q60670|SIK1_MOUSE Serine/threonine-protein kinase SIK1 OS=Mus musculus OX=10090 GN=Sik1 PE=1 SV=3 Length=779 Score = 225 bits (574), Expect = 3e-60, Method: Composition-based stats. Identities = 66/273 (24%), Positives = 108/273 (40%), Gaps = 29/273 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTL 954 + R LG+G+F V L + T VA+K + K + +E+ +++ L Sbjct 26 FYDVERTLGKGNFAVVKL----ARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLL 81 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAY 1013 H +IIK E + L +V E+ G + DYL + + + QI + Y Sbjct 82 NHPNIIKLYQVMETKD--MLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVEY 139 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 H H +HRDL N+LLD++ +K+ DFG G + SP + APE Sbjct 140 CHNHHIVHRDLKTENLLLDSNMDIKLADFGFGNFYKPGEP---LSTWCGSPP-YAAPEVF 195 Query 1074 KEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + ++ DVWS GV LY L+ P + L + + G Sbjct 196 EGKEYEGPQLDVWSLGVVLYVLVCGSLPFDGP---------------NLPTLRQRVLEG- 239 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 R P + L++ + + R T + Sbjct 240 RFRIPFFMSQDCETLIRRMLVVDPAKRITIAQI 272 Score = 200 bits (509), Expect = 5e-52, Method: Composition-based stats. Identities = 67/351 (19%), Positives = 117/351 (33%), Gaps = 40/351 (11%) Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620 ++IM A P Q RV ++ LG+G V R RV Sbjct 1 MVIMSEFSAVPSGTGQGQQKPLRVGFYDVE--RTLGKGNFAVVKLARHRV---------- 48 Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCV 678 + +V +K++D + D + Y LM ++H ++ ++ V Sbjct 49 --------------TKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPNIIKLYQVME 94 Query 679 RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGR 738 +VTE+ ++G + +L GH+ Q+ SA+ Y N ++VH ++ Sbjct 95 TKDMLYIVTEFAKNGEMFDYLTSN-GHLSENEARQKFWQILSAVEYCHNHHIVHRDLKTE 153 Query 739 NILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAM 795 N+LL ++ IKL+D G G P+ APE G + Sbjct 154 NLLLD-------SNMDIKLADFGFGNFYKPGEPLSTWCGSPPYAAPEVFEGKEYE-GPQL 205 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855 D W G L + P+ ++ + + R+P TL + L +P + Sbjct 206 DVWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCETLIRRMLVVDPAK 265 Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906 R + I + L D + G Sbjct 266 RITIAQIRQHRWMQADPTLLQQDDPAFDMQGYTSNLGDYNEQVLGIMQALG 316 >sp|Q6FKD4|PHO85_CANGA Negative regulator of the PHO system OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=PHO85 PE=3 SV=1 Length=302 Score = 212 bits (539), Expect = 3e-60, Method: Composition-based stats. Identities = 66/301 (22%), Positives = 118/301 (39%), Gaps = 36/301 (12%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 K++ LG G + V Y N TG VA+K +K D S +EI ++ Sbjct 1 MSSSQFKQLEKLGNGTYATV----YKGLNKSTGVYVALKEVKLDSEEGTPSTAIREISLM 56 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFA 1004 + L H++I++ E L LV EY+ L+ Y+ ++G + + F Sbjct 57 KELKHDNIVRLYDVI--HTENKLTLVFEYMDN-DLKKYMDSRTVGNAPRGLEMNLVKYFQ 113 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 Q+ EG+A+ H +HRDL +N+L+ +K+GDFGLA+A Sbjct 114 WQLLEGLAFCHENKILHRDLKPQNLLITKRGQLKLGDFGLARAFGIP---VNTFSSEVVT 170 Query 1065 VFWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTK-----FLELIGIA--- 1115 +++ AP+ L + + + D+WS G L E++T + + +G Sbjct 171 LWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDKMGTPNET 230 Query 1116 ----------QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 RL + L+ + + V L+ + R + + Sbjct 231 TWPGVTSLPKYNPNFQQRLPKDLKAELQPYVKEPLDDNVIDLLHGLLQLNPDMRLSAKQA 290 Query 1166 I 1166 + Sbjct 291 L 291 Score = 174 bits (441), Expect = 4e-47, Method: Composition-based stats. Identities = 49/271 (18%), Positives = 99/271 (37%), Gaps = 43/271 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + + QL LG GT VY+G + G + V LK Sbjct 1 MSSSQFKQLEKLGNGTYATVYKGLNKSTG------------------------VYVALKE 36 Query 644 LDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 + + SLM ++ H ++ ++ V + +V EY+++ L ++ Sbjct 37 VKLDSEEGTPSTAIREISLMKELKHDNIVRLYDVIHTENKLTLVFEYMDN-DLKKYMDSR 95 Query 703 -----RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + M QL L++ ++H ++ +N+L+ + G +KL Sbjct 96 TVGNAPRGLEMNLVKYFQWQLLEGLAFCHENKILHRDLKPQNLLITKRGQ-------LKL 148 Query 758 SDPGVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 D G+ + V + + AP+ L G+ + ST++D W G L E+ Sbjct 149 GDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM-GSRTYSTSIDIWSCGCILAEMITGKPL 207 Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQLATL 844 + + + + + E + P + +L Sbjct 208 FPGTNDEEQLKLIFDKMGTPNETTWPGVTSL 238 >sp|Q9HGY5|PHO85_CANAX Negative regulator of the PHO system OS=Candida albicans OX=5476 GN=PHO85 PE=3 SV=1 Length=326 Score = 213 bits (542), Expect = 3e-60, Method: Composition-based stats. Identities = 67/297 (23%), Positives = 120/297 (40%), Gaps = 30/297 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 +++ LGEG + V Y N TG +VA+K + D S +EI Sbjct 1 MTGSSSQFQQLEKLGEGTYATV----YKGRNRATGALVALKEISLDSEEGTPSTAIREIS 56 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQ 1005 +++ L HE+I+ E L LV EY+ L+ Y+ H + L + F Sbjct 57 LMKELDHENIVTLYDVI--HTENKLTLVFEYMDK-DLKKYMEVHGQQSALDLKVVKSFMF 113 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 Q+ +G+ + H +HRDL +N+L++N +K+GDFGLA+A + + + Sbjct 114 QLLKGIMFCHDNRVLHRDLKPQNLLINNKGELKLGDFGLARAFGIP---FNTFSNEVVTL 170 Query 1066 FWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTKFL--------------E 1110 ++ AP+ L + + + D+WS G E+ T + Sbjct 171 WYRAPDVLLGSRAYTTSIDIWSAGCIFAEMCTGKPLFPGTANEDQLIKIFRLMGTPNERT 230 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 GI+Q + + RL P+ + +L+++ + R T + Sbjct 231 WPGISQYTNYKNNWQIFVPQDLRLIVPNLDSMGL-NLLQSLLQMRPESRITARQALQ 286 Score = 168 bits (426), Expect = 8e-45, Method: Composition-based stats. Identities = 48/273 (18%), Positives = 99/273 (36%), Gaps = 42/273 (15%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + QL LG+GT VY+GR R G+ V LK + Sbjct 6 SQFQQLEKLGEGTYATVYKGRNRATGA------------------------LVALKEISL 41 Query 647 SHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL--RRER 703 + SLM ++ H ++ ++ V + +V EY++ L ++ ++ Sbjct 42 DSEEGTPSTAIREISLMKELDHENIVTLYDVIHTENKLTLVFEYMDK-DLKKYMEVHGQQ 100 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + + QL + + + ++H ++ +N+L+ G +KL D G+ Sbjct 101 SALDLKVVKSFMFQLLKGIMFCHDNRVLHRDLKPQNLLINNKGE-------LKLGDFGLA 153 Query 764 LG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + V + + AP+ L G+ + +T++D W G E+C + + Sbjct 154 RAFGIPFNTFSNEVVTLWYRAPDVLL-GSRAYTTSIDIWSAGCIFAEMCTGKPLFPGTAN 212 Query 820 PSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLT 850 + ++ E + P + T Sbjct 213 EDQLIKIFRLMGTPNERTWPGISQYTNYKNNWQ 245 >sp|Q9FZ59|PEPR2_ARATH Leucine-rich repeat receptor-like protein kinase PEPR2 OS=Arabidopsis thaliana OX=3702 GN=PEPR2 PE=1 SV=1 Length=1088 Score = 229 bits (583), Expect = 3e-60, Method: Composition-based stats. Identities = 69/298 (23%), Positives = 122/298 (41%), Gaps = 27/298 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G G V G+GE AVK L + K+EI+ + + H ++I+ Sbjct 800 IGRGAHGVVYRASL-----GSGEEYAVKKLIFAEHIRANQNMKREIETIGLVRHRNLIRL 854 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ 1017 + + + ++ +Y+P GSL D L R + + + A I G+AYLH Sbjct 855 ERFWMRKEDG--LMLYQYMPNGSLHDVLHRGNQGEAVLDWSARFNIALGISHGLAYLHHD 912 Query 1018 H---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRD+ N+L+D+D IGDFGLA+ + + + APE Sbjct 913 CHPPIIHRDIKPENILMDSDMEPHIGDFGLARILDDS---TVSTATVTGTTGYIAPENAY 969 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE-----LLE 1129 + SDV+S+GV L EL+T + + + ++ + ++ + +++ Sbjct 970 KTVRSKESDVYSYGVVLLELVTGKRALDRSFPEDINIVSWVRSVLSSYEDEDDTAGPIVD 1029 Query 1130 RGERLPRPDKCPCE----VYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183 D E V L C + RP+ +++ L + + + SV Sbjct 1030 PKLVDELLDTKLREQAIQVTDLALRCTDKRPENRPSMRDVVKDLTDLESFVRSTSGSV 1087 Score = 162 bits (411), Expect = 3e-39, Method: Composition-based stats. Identities = 58/322 (18%), Positives = 104/322 (32%), Gaps = 70/322 (22%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + +G+G VY L G+E V K++ Sbjct 790 ATDNLDDKYIIGRGAHGVVYRASLG-----------------------SGEEYAVK-KLI 825 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ER 703 H + V H +L + +R + +M+ +Y+ +G L L R + Sbjct 826 FAEHIRANQNMKREIETIGLVRHRNLIRLERFWMRKEDGLMLYQYMPNGSLHDVLHRGNQ 885 Query 704 GHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 G + W + +A ++ L+YL + ++H ++ NIL+ + Sbjct 886 GEAVLDWSARFNIALGISHGLAYLHHDCHPPIIHRDIKPENILMDSDMEPH-------IG 938 Query 759 DPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 D G+ +S ++APE S D + +G LLE+ G+ Sbjct 939 DFGLARILDDSTVSTATVTGTTGYIAPE--NAYKTVRSKESDVYSYGVVLLELV-TGKRA 995 Query 815 LQSRSPSEKEHFYQRQHRLPEPSCP--------------------------QLATLTSQC 848 L P + + L Q+ L +C Sbjct 996 LDRSFPEDINIVSWVRSVLSSYEDEDDTAGPIVDPKLVDELLDTKLREQAIQVTDLALRC 1055 Query 849 LTYEPTQRPSFRTILRDLTRLQ 870 P RPS R +++DLT L+ Sbjct 1056 TDKRPENRPSMRDVVKDLTDLE 1077 >sp|O54785|LIMK2_MOUSE LIM domain kinase 2 OS=Mus musculus OX=10090 GN=Limk2 PE=1 SV=2 Length=638 Score = 222 bits (566), Expect = 3e-60, Method: Composition-based stats. Identities = 79/309 (26%), Positives = 131/309 (42%), Gaps = 38/309 (12%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 S + +F L LG+G FG+ T+ TG+++ +K L C + + Sbjct 316 RCSSSYSQQIFRPCDLIHGEVLGKGFFGQ----AIKVTHKATGKVMVMKEL-IRCDEETQ 370 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQL 1000 + E+ ++R+L H +++K+ G +K L L+ EY+ G+L+D+L Q Sbjct 371 KTFLTEVKVMRSLDHPNVLKFIGVLYK--DKKLNLLTEYIEGGTLKDFLRSVDPFPWQQK 428 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG--------- 1051 + FA+ I GMAYLH+ IHRDL + N L+ D+ V + DFGL++ + E Sbjct 429 VRFAKGISSGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKRPPVEKA 488 Query 1052 --------HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS 1103 + R +W APE L + DV+SFG+ L E++ + Sbjct 489 TTKKRTLRKSDRKKRYTVVGNPYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPD 548 Query 1104 PPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFE 1163 + L+ G L + + P CP + L C + E RP F Sbjct 549 CLPRTLDF-----GLNVKLFWEKFV--------PTDCPPAFFPLAAICCKLEPESRPAFS 595 Query 1164 NLIPILKTV 1172 L + + Sbjct 596 KLEDSFEAL 604 Score = 198 bits (504), Expect = 4e-52, Method: Composition-based stats. Identities = 62/345 (18%), Positives = 112/345 (32%), Gaps = 62/345 (18%) Query 553 PQPGETSNLIIMRGARASPRTLN-LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 P P +++ + +L S S ++ LG+G + + Sbjct 294 PGPSSPKEPLLLSRDISRSESLRCSSSYSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKAT 353 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 G +V+K L + F +M + H ++ Sbjct 354 GK------------------------VMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVL 389 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 GV + + ++TEY+E G L +LR P K+ A+ ++S ++YL + ++ Sbjct 390 KFIGVLYKDKKLNLLTEYIEGGTLKDFLRSVD-PFPWQQKVRFAKGISSGMAYLHSMCII 448 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------------------------GAL 767 H ++ N L+ + ++D G+ Sbjct 449 HRDLNSHNCLI-------KLDKTVVVADFGLSRLIVEERKRPPVEKATTKKRTLRKSDRK 501 Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--FDGEAPLQSRSPSEKEH 825 R V W+APE L G S +D + FG L EI + R+ + Sbjct 502 KRYTVVGNPYWMAPEMLNG--KSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLN 559 Query 826 FY-QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + +P P L + C EP RP+F + L Sbjct 560 VKLFWEKFVPTDCPPAFFPLAAICCKLEPESRPAFSKLEDSFEAL 604 >sp|Q3U3Q1|ULK3_MOUSE Serine/threonine-protein kinase ULK3 OS=Mus musculus OX=10090 GN=Ulk3 PE=2 SV=1 Length=472 Score = 218 bits (554), Expect = 3e-60, Method: Composition-based stats. Identities = 66/282 (23%), Positives = 114/282 (40%), Gaps = 26/282 (9%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWK 945 + LG G + V T E+VA+K + K Sbjct 4 PSWGLPRLDGFILTERLGSGTYATVYKAYAK---KDTREVVAIKCVAKKSLNKASVENLL 60 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFA 1004 EI+IL+ + H HI++ K D ++ L+ME+ G L ++ R + +F Sbjct 61 TEIEILKGIRHPHIVQLKDFQWDND--NIYLIMEFCAGGDLSRFIHTRRILPEKVARVFM 118 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLD--NDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 QQ+ + +LH ++ H DL +N+LL +K+ DFG A+ + E + +R Sbjct 119 QQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLR---- 174 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 + APE + ++ D+WS GV LYE L S LE ++ Sbjct 175 GSPLYMAPEMVCRRQYDARVDLWSVGVILYEALFGQPPFASRSFSELE------EKIRSN 228 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 R+ E LP + + L++ E + + R +F++ Sbjct 229 RVIE-------LPLRPQLSLDCRDLLQRLLERDPARRISFKD 263 Score = 192 bits (487), Expect = 2e-51, Method: Composition-based stats. Identities = 67/293 (23%), Positives = 106/293 (36%), Gaps = 37/293 (13%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 LG GT VY+ + + V K L+ + Sbjct 14 FILTERLGSGTYATVYKAYAKKDTREVVAIKC------------------VAKKSLNKAS 55 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 + ++ + H H+ + ++ E+ G L ++ R +P Sbjct 56 VEN---LLTEIEILKGIRHPHIVQLKDFQWDNDNIYLIMEFCAGGDLSRFIHTRRI-LPE 111 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 V QQLASAL +L +N+ H ++ +NILL+ L P +KL+D G Sbjct 112 KVARVFMQQLASALQFLHERNISHLDLKPQNILLSSL-----EKPHLKLADFGFAQHMSP 166 Query 769 -REERV--ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 E+ V ++APE + +D W G L E F G+ P SRS SE E Sbjct 167 WDEKHVLRGSPLYMAPEMV--CRRQYDARVDLWSVGVILYEALF-GQPPFASRSFSELEE 223 Query 826 FYQRQHRLPEPSCPQLA----TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 + + P PQL+ L + L +P +R SF+ H Sbjct 224 KIRSNRVIELPLRPQLSLDCRDLLQRLLERDPARRISFKDFFAHPWVDLEHMP 276 >sp|A5GFW1|AURKA_PIG Aurora kinase A OS=Sus scrofa OX=9823 GN=AURKA PE=3 SV=1 Length=402 Score = 215 bits (548), Expect = 3e-60, Method: Composition-based stats. Identities = 68/322 (21%), Positives = 120/322 (37%), Gaps = 32/322 (10%) Query 851 YEPTQRPSFRTILRDLTRL--QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 P RP T + + +N + S + + R LG+G F Sbjct 85 PRPVSRPLSNTQQSEQPQPAAPGNNPEKEAASKQKNEESKKRQWALEDFEIGRPLGKGKF 144 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHIIKYKGCC 966 G V L + ++A+K L + ++E++I L H +I++ G Sbjct 145 GNVYL----AREKQSKFILALKVLFKTQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYF 200 Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 D + L++EY PLG++ L + + + ++ ++Y H++ IHRD+ Sbjct 201 HDAT--RVYLILEYAPLGAVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIK 258 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 N+LL + +KI DFG + P R + + PE ++ D+W Sbjct 259 PENLLLGSAGELKIADFGWSVHAPSSR-----RTTLCGTLDYLPPEMIEGRMHDEKVDLW 313 Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 S GV YE L ++ T + + R E PD P Sbjct 314 SLGVLCYEFLVGKPPFEA---------------NTYQETYKRISRVE-FTFPDFVPEGAR 357 Query 1146 HLMKNCWETEASFRPTFENLIP 1167 L+ + S RPT + ++ Sbjct 358 DLISRLLKHNPSHRPTLKEVLE 379 Score = 183 bits (465), Expect = 4e-49, Method: Composition-based stats. Identities = 62/348 (18%), Positives = 123/348 (35%), Gaps = 45/348 (13%) Query 546 SLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYE 605 + ++ PQP N + A + + + + ++ LG+G NVY Sbjct 94 NTQQSEQPQPAAPGNNPE-KEAASKQKNEESKKRQW---ALEDFEIGRPLGKGKFGNVYL 149 Query 606 GRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD---IALAFYETASLM 662 R++ + + LKVL + + + + Sbjct 150 A------------------------REKQSKFILALKVLFKTQLEKAGVEHQLRREVEIQ 185 Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASAL 722 S + H ++ ++G ++ EY G + L++ +LA+AL Sbjct 186 SHLRHPNILRLYGYFHDATRVYLILEYAPLGAVYRELQKL-SKFDEQRTATYITELANAL 244 Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--REERVERIPWLA 780 SY +K ++H ++ N+LL G++ +K++D G + A S R + +L Sbjct 245 SYCHSKRVIHRDIKPENLLL-------GSAGELKIADFGWSVHAPSSRRTTLCGTLDYLP 297 Query 781 PECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPSCP 839 PE + G + +D W G E G+ P ++ + E + + P+ Sbjct 298 PEMIEGRMH--DEKVDLWSLGVLCYEFLV-GKPPFEANTYQETYKRISRVEFTFPDFVPE 354 Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 L S+ L + P+ RP+ + +L A S Sbjct 355 GARDLISRLLKHNPSHRPTLKEVLEHPWITANSKPASSHKKESTSKQP 402 >sp|O42565|LIMK1_XENLA LIM domain kinase 1 OS=Xenopus laevis OX=8355 GN=limk1 PE=2 SV=1 Length=615 Score = 221 bits (564), Expect = 3e-60, Method: Composition-based stats. Identities = 82/365 (22%), Positives = 144/365 (39%), Gaps = 32/365 (9%) Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885 H P P A + + P R + + + + +S Sbjct 243 IEHDPHETPTMPSPC-AEIAVR--RQRPVMRSCSIDRSPGSSCVGSPSCSRRDMSRSESV 299 Query 886 ASD---PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 + +F L LG G FG+ T+ TGE++ +K L + + Sbjct 300 RTVTGVHRIFRPSDLIPGEVLGRGCFGQ----AIKVTHRVTGEVMVMKEL-IRFDEETQR 354 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQL 1000 + +E+ ++R L H H++K+ G +K L + EY+P G+LR + Q Sbjct 355 TFLKEVKVMRCLEHPHVLKFIGVLYK--DKRLNFITEYIPGGTLRRVIKSMDTHCPWNQR 412 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE- 1059 + FA+ I GM YLH+ + IHRDL + N L+ D + + +FGL++ +PE R Sbjct 413 VSFARDIAAGMTYLHSMNIIHRDLNSHNCLVREDGGLVVANFGLSRLIPEETRDLRKDRR 472 Query 1060 ---DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 +W APE + + + DV+SFG+ + E++ ++ + ++ Sbjct 473 KRYTVVGNPYWMAPEMINGRSYDESVDVFSFGIVICEIIGLVNADPDYLPRTMDFG---- 528 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 L + L+R P CP + C + + RP F L L ++ Sbjct 529 -----LNVRAFLDR----FCPPNCPPGFFPSAVLCCDLDPEKRPRFSQLQLWLDSLLRHL 579 Query 1177 QGQAP 1181 Q P Sbjct 580 NLQLP 584 Score = 198 bits (504), Expect = 2e-52, Method: Composition-based stats. Identities = 64/343 (19%), Positives = 123/343 (36%), Gaps = 50/343 (15%) Query 547 LRRCCLPQPGETSNLIIMRGARAS-PRTLNLSQLS-FHRV-DQKEITQLSHLGQGTRTNV 603 +R C + + +S + +R R+ ++ ++ HR+ ++ LG+G Sbjct 269 MRSCSIDRSPGSSCVGSPSCSRRDMSRSESVRTVTGVHRIFRPSDLIPGEVLGRGCFGQA 328 Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663 + RV G +V+K L + F + +M Sbjct 329 IKVTHRVTGE------------------------VMVMKELIRFDEETQRTFLKEVKVMR 364 Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723 + H H+ GV + +TEY+ G L ++ H P ++ A+ +A+ ++ Sbjct 365 CLEHPHVLKFIGVLYKDKRLNFITEYIPGGTLRRVIKSMDTHCPWNQRVSFARDIAAGMT 424 Query 724 YLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-----------ER 772 YL + N++H ++ N L+ G +++ G+ Sbjct 425 YLHSMNIIHRDLNSHNCLVREDGGLV-------VANFGLSRLIPEETRDLRKDRRKRYTV 477 Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI--CFDGEAPLQSRSPSEKEHFYQRQ 830 V W+APE + G S ++D + FG + EI + + R+ + Sbjct 478 VGNPYWMAPEMING--RSYDESVDVFSFGIVICEIIGLVNADPDYLPRTMDFGLNVRAFL 535 Query 831 HRLPEPSCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 R P+CP C +P +RP F + L L H Sbjct 536 DRFCPPNCPPGFFPSAVLCCDLDPEKRPRFSQLQLWLDSLLRH 578 >sp|Q9LMP1|WAK2_ARATH Wall-associated receptor kinase 2 OS=Arabidopsis thaliana OX=3702 GN=WAK2 PE=1 SV=1 Length=732 Score = 224 bits (571), Expect = 4e-60, Method: Composition-based stats. Identities = 80/364 (22%), Positives = 135/364 (37%), Gaps = 24/364 (7%) Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR------LQPHNLADV 877 E+F Q L + L CL + R + + + +Q + A Sbjct 325 EYFRWTQIFLGTTIGFSVIMLGISCLQQKIKHRKNTELRQKFFEQNGGGMLIQRVSGAGP 384 Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 V+ + R LG+G G V +VA+K + Sbjct 385 SNVDVKIFTEKGMKEATNGYHESRILGQGGQGTVYKGIL-----PDNSIVAIKKARLGNR 439 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RH 993 Q + E+ +L + H +++K GCC + E L LV E++ G+L D+L Sbjct 440 SQ-VEQFINEVLVLSQINHRNVVKVLGCCLE-TEVPL-LVYEFINSGTLFDHLHGSLYDS 496 Query 994 SIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 S+ L A ++ +AYLH+ IHRD+ N+LLD + K+ DFG ++ +P Sbjct 497 SLTWEHRLRIATEVAGSLAYLHSSASIPIIHRDIKTANILLDKNLTAKVADFGASRLIPM 556 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFL 1109 E ++ + + PE SDV+SFGV L ELL+ + P Sbjct 557 DKE--QLTTIVQGTLGYLDPEYYNTGLLNEKSDVYSFGVVLMELLSGQKALCFERPHCPK 614 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 L+ R E+++ + E + C RP + + L Sbjct 615 NLVSCFASATKNNRFHEIIDGQVMNEDNQREIQEAARIAAECTRLMGEERPRMKEVAAEL 674 Query 1170 KTVH 1173 + + Sbjct 675 EALR 678 Score = 204 bits (518), Expect = 2e-53, Method: Composition-based stats. Identities = 63/330 (19%), Positives = 120/330 (36%), Gaps = 50/330 (15%) Query 503 RKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLI 562 RK E + G F + + LQ + + LR+ Q G ++ Sbjct 320 RKVRPEYFRWTQIFLGTTIGFSVIMLGISCLQQKIKHRKNT--ELRQKFFEQNG--GGML 375 Query 563 IMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620 I R + A P +++ + + + LGQG + VY+G L Sbjct 376 IQRVSGAGPSNVDVKIFTEKGMKEATNGYHESRILGQGGQGTVYKGILPDNSI------- 428 Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG 680 V +K + F ++SQ++H ++ V G C+ Sbjct 429 ------------------VAIKKARLGNRSQVEQFINEVLVLSQINHRNVVKVLGCCLET 470 Query 681 PENIMVTEYVEHGPLDVWLRRE--RGHVPMAWKMVVAQQLASALSYLENK---NLVHGNV 735 ++V E++ G L L + ++ +A ++A +L+YL + ++H ++ Sbjct 471 EVPLLVYEFINSGTLFDHLHGSLYDSSLTWEHRLRIATEVAGSLAYLHSSASIPIIHRDI 530 Query 736 CGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANS 790 NILL + + K++D G +E++ + +L PE G Sbjct 531 KTANILLDK-------NLTAKVADFGASRLIPMDKEQLTTIVQGTLGYLDPEYYNTGL-- 581 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 L+ D + FG L+E+ +A R Sbjct 582 LNEKSDVYSFGVVLMELLSGQKALCFERPH 611 >sp|P14056|ARAF_RAT Serine/threonine-protein kinase A-Raf OS=Rattus norvegicus OX=10116 GN=Araf PE=1 SV=1 Length=604 Score = 221 bits (563), Expect = 4e-60, Method: Composition-based stats. Identities = 75/326 (23%), Positives = 132/326 (40%), Gaps = 27/326 (8%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 + P + R + + + ++ ++ +G G FG V Sbjct 266 KSPHSKLPAEQRERKSLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 325 Query 915 CYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 + VAVK LK A + +K E+ +LR H +I+ + G G Sbjct 326 RWHG-------DVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG--- 375 Query 974 LQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031 ++ ++ SL +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L Sbjct 376 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 435 Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFG 1088 VKIGDFGLA V + E V W A E ++ + + SDV+++G Sbjct 436 HEGLTVKIGDFGLA-TVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYG 494 Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148 V LYEL+T ++ + + +G ++ CP + L+ Sbjct 495 VVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSK----------IFSNCPKAMRRLL 544 Query 1149 KNCWETEASFRPTFENLIPILKTVHE 1174 +C + + RP F ++ ++ + Sbjct 545 TDCLKFQREERPLFPQILATIELLQR 570 Score = 206 bits (523), Expect = 6e-55, Method: Composition-based stats. Identities = 70/366 (19%), Positives = 122/366 (33%), Gaps = 53/366 (14%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQL-SFHRVDQKEITQLSHLGQGTRTNVYEG 606 + P E + + + L + V E+ L +G G+ V+ G Sbjct 266 KSPHSKLPAEQRERKSLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 325 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH--HDIALAFYETASLMSQ 664 R + V +KVL + + A AF ++ + Sbjct 326 RWHGD---------------------------VAVKVLKVAQPTAEQAQAFKNEMQVLRK 358 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 H ++ G R ++T++ E L L M + VA+Q A + Y Sbjct 359 TRHVNILLFMGFMTRPG-FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDY 417 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778 L KN++H ++ NI L +K+ D G+ GA E+ + W Sbjct 418 LHAKNIIHRDLKSNNIFLHEGL-------TVKIGDFGLATVKTRWSGAQPLEQPSGSVLW 470 Query 779 LAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP- 836 +A E + N S D + +G L E+ G P ++ F + L Sbjct 471 MAAEVIRMQDPNPYSFQSDVYAYGVVLYELM-TGSLPYSHIGSRDQIIFMVGRGYLSPDL 529 Query 837 -----SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 +CP+ + L + CL ++ +RP F IL + LQ + + S Sbjct 530 SKIFSNCPKAMRRLLTDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQA 589 Query 891 VFHKRY 896 Sbjct 590 DELPAC 595 >sp|P10398|ARAF_HUMAN Serine/threonine-protein kinase A-Raf OS=Homo sapiens OX=9606 GN=ARAF PE=1 SV=2 Length=606 Score = 221 bits (563), Expect = 4e-60, Method: Composition-based stats. Identities = 74/326 (23%), Positives = 131/326 (40%), Gaps = 27/326 (8%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 + P ++ R + + + ++ ++ +G G FG V Sbjct 268 KSPHSKSPAEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 327 Query 915 CYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 + VAVK LK + +K E+ +LR H +I+ + G G Sbjct 328 RWHG-------DVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG--- 377 Query 974 LQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031 ++ ++ SL +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L Sbjct 378 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 437 Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFG 1088 VKIGDFGLA V + E V W A E ++ + + SDV+++G Sbjct 438 HEGLTVKIGDFGLA-TVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYG 496 Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148 V LYEL+T + + + +G ++ CP + L+ Sbjct 497 VVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSK----------ISSNCPKAMRRLL 546 Query 1149 KNCWETEASFRPTFENLIPILKTVHE 1174 +C + + RP F ++ ++ + Sbjct 547 SDCLKFQREERPLFPQILATIELLQR 572 Score = 207 bits (528), Expect = 1e-55, Method: Composition-based stats. Identities = 72/366 (20%), Positives = 122/366 (33%), Gaps = 53/366 (14%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQL-SFHRVDQKEITQLSHLGQGTRTNVYEG 606 + P E + + + L + V E+ L +G G+ V+ G Sbjct 268 KSPHSKSPAEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 327 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH--HDIALAFYETASLMSQ 664 R + V +KVL S + A AF ++ + Sbjct 328 RWHGD---------------------------VAVKVLKVSQPTAEQAQAFKNEMQVLRK 360 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 H ++ G R ++T++ E L L M + VA+Q A + Y Sbjct 361 TRHVNILLFMGFMTRPG-FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDY 419 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778 L KN++H ++ NI L +K+ D G+ GA E+ + W Sbjct 420 LHAKNIIHRDLKSNNIFLHEGL-------TVKIGDFGLATVKTRWSGAQPLEQPSGSVLW 472 Query 779 LAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP- 836 +A E + N S D + +G L E+ G P ++ F + L Sbjct 473 MAAEVIRMQDPNPYSFQSDVYAYGVVLYELM-TGSLPYSHIGCRDQIIFMVGRGYLSPDL 531 Query 837 -----SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 +CP+ + L S CL ++ +RP F IL + LQ + + S Sbjct 532 SKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQA 591 Query 891 VFHKRY 896 Sbjct 592 DELPAC 597 >sp|D3ZHP7|ULK3_RAT Serine/threonine-protein kinase ULK3 OS=Rattus norvegicus OX=10116 GN=Ulk3 PE=1 SV=1 Length=472 Score = 218 bits (554), Expect = 4e-60, Method: Composition-based stats. Identities = 67/280 (24%), Positives = 114/280 (41%), Gaps = 26/280 (9%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQE 947 + LG G + V T E+VA+K + K E Sbjct 6 WGLPRLDGFILTERLGSGTYATVYKAYAK---KATREVVAIKCVAKKSLNKASVENLLTE 62 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQ 1006 I+IL+ + H HI++ K D ++ L+ME+ G L ++ R + +F QQ Sbjct 63 IEILKGIRHPHIVQLKDFQWDND--NIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQ 120 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLD--NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 + + +LH ++ H DL +N+LL +K+ DFG A+ + E + +R Sbjct 121 LASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLR----GS 176 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 + APE + ++ D+WS GV LYE L S LE ++ R+ Sbjct 177 PLYMAPEMVCRRQYDARVDLWSVGVILYEALFGQPPFASRSFSELE------EKIRSNRV 230 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 E LP + + L++ E + S R +F++ Sbjct 231 IE-------LPLRPQLSLDCRDLLQRLLERDPSHRISFQD 263 Score = 191 bits (486), Expect = 3e-51, Method: Composition-based stats. Identities = 67/293 (23%), Positives = 105/293 (36%), Gaps = 37/293 (13%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 LG GT VY+ + V K L+ + Sbjct 14 FILTERLGSGTYATVYKAYAKKATREVVAIKC------------------VAKKSLNKAS 55 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 + ++ + H H+ + ++ E+ G L ++ R +P Sbjct 56 VEN---LLTEIEILKGIRHPHIVQLKDFQWDNDNIYLIMEFCAGGDLSRFIHTRRI-LPE 111 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 V QQLASAL +L +N+ H ++ +NILL+ L P +KL+D G Sbjct 112 KVARVFMQQLASALQFLHERNISHLDLKPQNILLSSL-----EKPHLKLADFGFAQHMSP 166 Query 769 -REERV--ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 E+ V ++APE + +D W G L E F G+ P SRS SE E Sbjct 167 WDEKHVLRGSPLYMAPEMV--CRRQYDARVDLWSVGVILYEALF-GQPPFASRSFSELEE 223 Query 826 FYQRQHRLPEPSCPQLA----TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 + + P PQL+ L + L +P+ R SF+ H Sbjct 224 KIRSNRVIELPLRPQLSLDCRDLLQRLLERDPSHRISFQDFFAHPWVDLEHMP 276 >sp|P11346|KRAF1_DROME Raf homolog serine/threonine-protein kinase Raf OS=Drosophila melanogaster OX=7227 GN=Raf PE=1 SV=6 Length=739 Score = 224 bits (571), Expect = 4e-60, Method: Composition-based stats. Identities = 79/291 (27%), Positives = 124/291 (43%), Gaps = 27/291 (9%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQ 946 + + +G G FG V + VAVK L P +K Sbjct 420 ENWNILAEEILIGPRIGSGSFGTVYRAHWHG-------PVAVKTLNVKTPSPAQLQAFKN 472 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFA 1004 E+ +L+ H +I+ + GC + SL +V ++ SL ++ L L+ Sbjct 473 EVAMLKKTRHCNILLFMGCV---SKPSLAIVTQWCEGSSLYKHVHVSETKFKLNTLIDIG 529 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 +Q+ +GM YLHA++ IHRDL + N+ L D VKIGDFGLA A + Sbjct 530 RQVAQGMDYLHAKNIIHRDLKSNNIFLHEDLSVKIGDFGLATA-KTRWSGEKQANQPTGS 588 Query 1065 VFWYAPECLKE---YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 + W APE ++ + + SDV++FG+ +YELL C K L + +G Sbjct 589 ILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRG---- 644 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 LL R D P + L ++C + RP F L+ +L+ + Sbjct 645 -----LLRPDMSQVRSD-APQALKRLAEDCIKYTPKDRPLFRPLLNMLENM 689 Score = 205 bits (522), Expect = 8e-54, Method: Composition-based stats. Identities = 68/373 (18%), Positives = 116/373 (31%), Gaps = 58/373 (16%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQL----SFHRVDQKEITQLSHLGQGTRTNVYEGRL 608 P N R A S + L L + +EI +G G+ VY Sbjct 389 PTSTLKHNRPRARSADESNKNLLLRDAKSSEENWNILAEEILIGPRIGSGSFGTVYRAHW 448 Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD---PSHHDIALAFYETASLMSQV 665 V +K L+ PS + AF +++ + Sbjct 449 HGP---------------------------VAVKTLNVKTPSPAQLQ-AFKNEVAMLKKT 480 Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL 725 H ++ G CV P +VT++ E L + + + + +Q+A + YL Sbjct 481 RHCNILLFMG-CVSKPSLAIVTQWCEGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYL 539 Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL------SREERVERIPWL 779 KN++H ++ NI L +K+ D G+ + I W+ Sbjct 540 HAKNIIHRDLKSNNIFLHE-------DLSVKIGDFGLATAKTRWSGEKQANQPTGSILWM 592 Query 780 APECLPGGA-NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838 APE + N S D + FG + E+ + P S ++ F + L Sbjct 593 APEVIRMQELNPYSFQSDVYAFGIVMYELLAEC-LPYGHISNKDQILFMVGRGLLRPDMS 651 Query 839 -------PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV 891 L L C+ Y P RP FR +L L + + + + Sbjct 652 QVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENMLRTLPKIHRSASEPNLTQSQLQ 711 Query 892 FHKRYLKKIRDLG 904 + Sbjct 712 NDEFLYLPSPKTP 724 >sp|P04627|ARAF_MOUSE Serine/threonine-protein kinase A-Raf OS=Mus musculus OX=10090 GN=Araf PE=1 SV=2 Length=604 Score = 221 bits (563), Expect = 4e-60, Method: Composition-based stats. Identities = 75/326 (23%), Positives = 132/326 (40%), Gaps = 27/326 (8%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 + P + R + + + ++ ++ +G G FG V Sbjct 266 KSPHSKLPSEQRERKSLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 325 Query 915 CYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 + VAVK LK A + +K E+ +LR H +I+ + G G Sbjct 326 RWHG-------DVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPG--- 375 Query 974 LQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031 ++ ++ SL +L + QL+ A+Q +GM YLHA++ IHRDL + N+ L Sbjct 376 FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFL 435 Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK---EYKFYYASDVWSFG 1088 VKIGDFGLA V + E V W A E ++ + + SDV+++G Sbjct 436 HEGLTVKIGDFGLA-TVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYG 494 Query 1089 VTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148 V LYEL+T ++ + + +G ++ CP + L+ Sbjct 495 VVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSK----------IFSNCPKAMRRLL 544 Query 1149 KNCWETEASFRPTFENLIPILKTVHE 1174 +C + + RP F ++ ++ + Sbjct 545 TDCLKFQREERPLFPQILATIELLQR 570 Score = 206 bits (524), Expect = 4e-55, Method: Composition-based stats. Identities = 70/366 (19%), Positives = 122/366 (33%), Gaps = 53/366 (14%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQL-SFHRVDQKEITQLSHLGQGTRTNVYEG 606 + P E + + + L + V E+ L +G G+ V+ G Sbjct 266 KSPHSKLPSEQRERKSLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRG 325 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH--HDIALAFYETASLMSQ 664 R + V +KVL + + A AF ++ + Sbjct 326 RWHGD---------------------------VAVKVLKVAQPTAEQAQAFKNEMQVLRK 358 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 H ++ G R ++T++ E L L M + VA+Q A + Y Sbjct 359 TRHVNILLFMGFMTRPG-FAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDY 417 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPW 778 L KN++H ++ NI L +K+ D G+ GA E+ + W Sbjct 418 LHAKNIIHRDLKSNNIFLHEGL-------TVKIGDFGLATVKTRWSGAQPLEQPSGSVLW 470 Query 779 LAPECLPGG-ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEP- 836 +A E + N S D + +G L E+ G P ++ F + L Sbjct 471 MAAEVIRMQDPNPYSFQSDVYAYGVVLYELM-TGSLPYSHIGSRDQIIFMVGRGYLSPDL 529 Query 837 -----SCPQ-LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPT 890 +CP+ + L + CL ++ +RP F IL + LQ + + S Sbjct 530 SKIFSNCPKAMRRLLTDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQA 589 Query 891 VFHKRY 896 Sbjct 590 DELPAC 595 >sp|O08678|MARK1_RAT Serine/threonine-protein kinase MARK1 OS=Rattus norvegicus OX=10116 GN=Mark1 PE=1 SV=1 Length=793 Score = 225 bits (573), Expect = 4e-60, Method: Composition-based stats. Identities = 70/248 (28%), Positives = 109/248 (44%), Gaps = 13/248 (5%) Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 + + + ++ ++ H + + +G+G+F KV L + TG Sbjct 28 HIPPTKSSSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKL----ARHVLTG 83 Query 925 EMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPL 983 VAVK + K P +E+ I++ L H +I+K E EK+L LVMEY Sbjct 84 REVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIE--TEKTLYLVMEYASG 141 Query 984 GSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 G + DYL H + + +QI + Y H + +HRDL A N+LLD D +KI DF Sbjct 142 GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADF 201 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSS 1101 G + G++ + + APE + K+ DVWS GV LY L++ Sbjct 202 GFSNEFTVGNKL----DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF 257 Query 1102 QSPPTKFL 1109 K L Sbjct 258 DGQNLKEL 265 Score = 181 bits (458), Expect = 2e-45, Method: Composition-based stats. Identities = 53/287 (18%), Positives = 93/287 (32%), Gaps = 40/287 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 +G+G V R + G V +K++D + Sbjct 59 NYRLQKTIGKGNFAKVKLARHVLTGR------------------------EVAVKIIDKT 94 Query 648 HHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + + +M ++H ++ + V +V EY G + +L G Sbjct 95 QLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAH-GR 153 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 + +Q+ SA+ Y K +VH ++ N+LL IK++D G Sbjct 154 MKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLD-------ADMNIKIADFGFSNE 206 Query 766 AL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + P+ APE G +D W G L + G P ++ E Sbjct 207 FTVGNKLDTFCGSPPYAAPELFQGKKYD-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKE 264 Query 823 KEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 R +R+P L + L P +R S I++D Sbjct 265 LRERVLRGKYRVPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWM 311 >sp|Q5N942|SAPK4_ORYSJ Serine/threonine-protein kinase SAPK4 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK4 PE=2 SV=2 Length=360 Score = 214 bits (544), Expect = 4e-60, Method: Composition-based stats. Identities = 73/276 (26%), Positives = 113/276 (41%), Gaps = 26/276 (9%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 + +RD+G G+FG L N T E+VAVK + + G + +EI R+ Sbjct 1 MEKYEAVRDIGSGNFGVARLM----RNRETRELVAVKCI--ERGHRIDENVYREIINHRS 54 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012 L H +II++K L +VME+ G L D + R + F QQ+ G++ Sbjct 55 LRHPNIIRFKEVILTPTH--LMIVMEFAAGGELFDRICDRGRFSEDEARYFFQQLICGVS 112 Query 1013 YLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 Y H HRDL NVLLD +KI DFG +K + R + +P + AP Sbjct 113 YCHHMQICHRDLKLENVLLDGSPAPRLKICDFGYSK---SSVLHSRPKSAVGTPA-YIAP 168 Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E L ++ +DVWS GVTLY +L + I + ++ + + Sbjct 169 EVLSRREYDGKLADVWSCGVTLYVMLVGAYPFEDQDDPKNIRKTIQRIMSVQYKIPDYV- 227 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 E L+ + R T + + Sbjct 228 ---------HISAECKQLIARIFVNNPLRRITMKEI 254 Score = 161 bits (407), Expect = 6e-42, Method: Composition-based stats. Identities = 48/268 (18%), Positives = 87/268 (32%), Gaps = 17/268 (6%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 R+R V +K ++ H I Y + H ++ V + ++V E+ Sbjct 22 RNRETRELVAVKCIERGHR-IDENVYREIINHRSLRHPNIIRFKEVILTPTHLMIVMEFA 80 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L + +RG QQL +SY + + H ++ N+LL Sbjct 81 AGGELFDRI-CDRGRFSEDEARYFFQQLICGVSYCHHMQICHRDLKLENVLLD-----GS 134 Query 751 TSPFIKLSDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +P +K+ D G ++ + V ++APE L D W G TL + Sbjct 135 PAPRLKICDFGYSKSSVLHSRPKSAVGTPAYIAPEVLSRREYD-GKLADVWSCGVTLYVM 193 Query 808 CFDGEAPLQSRSPSEKEH----FYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRT 861 P Q+++P+ + L ++ P +R + + Sbjct 194 LVGAYPFEDQDDPKNIRKTIQRIMSVQYKIPDYVHISAECKQLIARIFVNNPLRRITMKE 253 Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDP 889 I L+ T D Sbjct 254 IKSHPWFLKNLPRELTETAQAMYYRRDN 281 >sp|O65924|Y2921_ARATH Putative leucine-rich repeat receptor-like protein kinase At2g19210 OS=Arabidopsis thaliana OX=3702 GN=At2g19210 PE=1 SV=1 Length=881 Score = 226 bits (577), Expect = 4e-60, Method: Composition-based stats. Identities = 61/295 (21%), Positives = 121/295 (41%), Gaps = 18/295 (6%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 + K R LG+G FGKV + VAVK L ++ Q + Sbjct 564 RYYKYSEVVKVTNNFERVLGQGGFGKVYHGVL------NDDQVAVKIL-SESSAQGYKEF 616 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLL 1001 + E+++L ++H+++ G C + K + L+ E++ G+L DYL + + + L Sbjct 617 RAEVELLLRVHHKNLTALIGYCHEG--KKMALIYEFMANGTLGDYLSGEKSYVLSWEERL 674 Query 1002 LFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 + +G+ YLH + RD+ N+L++ KI DFGL+++V Sbjct 675 QISLDAAQGLEYLHNGCKPPIVQRDVKPANILINEKLQAKIADFGLSRSVALDGNNQDT- 733 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGIAQ 1116 + + PE K SD++SFGV L E+++ + + + + Sbjct 734 TAVAGTIGYLDPEYHLTQKLSEKSDIYSFGVVLLEVVSGQPVIARSRTTAENIHITDRVD 793 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 ++ + +++ ++ + C + + RPT +++ LK Sbjct 794 LMLSTGDIRGIVDPKLGERFDAGSAWKITEVAMACASSSSKNRPTMSHVVAELKE 848 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 61/274 (22%), Positives = 97/274 (35%), Gaps = 45/274 (16%) Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 G RA P + V + LGQG VY G L + Sbjct 553 GVRAGPLDTTKRYYKYSEVVKVTNNFERVLGQGGFGKVYHGVLNDD-------------- 598 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 +V +K+L S F L+ +V H +L + G C G + + Sbjct 599 ------------QVAVKILSESSAQGYKEFRAEVELLLRVHHKNLTALIGYCHEGKKMAL 646 Query 686 VTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNIL 741 + E++ +G L +L E+ + + ++ ++ A L YL N +V +V NIL Sbjct 647 IYEFMANGTLGDYLSGEKSYVLSWEERLQISLDAAQGLEYLHNGCKPPIVQRDVKPANIL 706 Query 742 LARLGLAEGTSPFIKLSDPGVGLGA------LSREERVERIPWLAPECLPGGANSLSTAM 795 + A K++D G+ I +L PE LS Sbjct 707 INEKLQA-------KIADFGLSRSVALDGNNQDTTAVAGTIGYLDPEY--HLTQKLSEKS 757 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 D + FG LLE+ +SR+ +E H R Sbjct 758 DIYSFGVVLLEVVSGQPVIARSRTTAENIHITDR 791 >sp|Q61036|PAK3_MOUSE Serine/threonine-protein kinase PAK 3 OS=Mus musculus OX=10090 GN=Pak3 PE=1 SV=2 Length=559 Score = 220 bits (560), Expect = 4e-60, Method: Composition-based stats. Identities = 62/275 (23%), Positives = 108/275 (39%), Gaps = 23/275 (8%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 K+ + +G+G G V Y + TG+ VA+K + P+ + EI ++R Sbjct 279 PKKKYTRFEKIGQGASGTV----YTALDIATGQEVAIKQMNLQQQPK-KELIINEILVMR 333 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 + +I+ Y E L +VMEY+ GSL D + + Q+ ++ + + Sbjct 334 ENKNPNIVNYLDSYLVGDE--LWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALD 391 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 +LH+ IHRD+ + N+LL D VK+ DFG + R +W APE Sbjct 392 FLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITP---EQSKRSTMVGTPYWMAPEV 448 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + D+WS G+ E++ PP + T Sbjct 449 VTRKAYGPKVDIWSLGIMAIEMV-----EGEPPYLNENPLRALYLIATNGT--------P 495 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L P++ + C E + R + + L+ Sbjct 496 ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQ 530 Score = 178 bits (452), Expect = 5e-46, Method: Composition-based stats. Identities = 59/333 (18%), Positives = 107/333 (32%), Gaps = 56/333 (17%) Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRV------------DQKEITQLSHLGQGTRTN 602 P N R + R S+++ + +K+ T+ +GQG Sbjct 237 PPSAENANSTTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGT 296 Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLM 662 VY D V +K ++ +M Sbjct 297 VY------------------------TALDIATGQEVAIKQMNLQQQPKKELIINEILVM 332 Query 663 SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASAL 722 + + ++ + G E +V EY+ G L + + V ++ AL Sbjct 333 RENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVV--TETCMDEGQIAAVCRECLQAL 390 Query 723 SYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREERVERIPW 778 +L + ++H ++ NILL G +KL+D G R V W Sbjct 391 DFLHSNQVIHRDIKSDNILL-------GMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW 443 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL----P 834 +APE + A +D W G +E+ +GE P + +P + P Sbjct 444 MAPEVVTRKA--YGPKVDIWSLGIMAIEMV-EGEPPYLNENPLRALYLIATNGTPELQNP 500 Query 835 EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 E ++CL + +R S + +L+ Sbjct 501 ERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPF 533 >sp|Q39030|KPK2_ARATH Serine/threonine-protein kinase AtPK2/AtPK19 OS=Arabidopsis thaliana OX=3702 GN=ATPK2 PE=1 SV=2 Length=471 Score = 217 bits (553), Expect = 4e-60, Method: Composition-based stats. Identities = 71/281 (25%), Positives = 117/281 (42%), Gaps = 37/281 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960 +G+G FGKV Y T E+ A+K ++ D H K E DIL + H I+ Sbjct 146 VGQGAFGKV----YQVRKKDTSEIYAMKVMRKDKIVEKNHAEYMKAERDILTKIDHPFIV 201 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHY 1019 + K Q + L LV++++ G L L + ++ +I +++LH + Sbjct 202 QLKYSF--QTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGI 259 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDL N+L+D D V + DFGLAK E + + APE ++ Sbjct 260 MHRDLKPENILMDVDGHVMLTDFGLAKEFEENTRSNSM----CGTTEYMAPEIVRGKGHD 315 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 A+D WS G+ LYE+LT K + ++++ +L P Sbjct 316 KAADWWSVGILLYEMLTGKPPFLGSKGKIQQ---------------KIVKDKIKL--PQF 358 Query 1140 CPCEVYHLMKNCWETEASFR----PT-FENL--IPILKTVH 1173 E + L+K + E R P+ E + K ++ Sbjct 359 LSNEAHALLKGLLQKEPERRLGSGPSGAEEIKKHKWFKAIN 399 Score = 161 bits (407), Expect = 7e-41, Method: Composition-based stats. Identities = 52/276 (19%), Positives = 105/276 (38%), Gaps = 35/276 (13%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V ++ L +GQG VY ++R + + + K+ +D K+ Sbjct 135 VGIEDFEVLKVVGQGAFGKVY--QVRKKDTSEIYAMKVMRKD----------------KI 176 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 ++ +H + A +++++ H + + +V +++ G L L + Sbjct 177 VEKNHAEYMKA---ERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQ- 232 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 G V ++ SA+S+L K ++H ++ NIL+ G + L+D G+ Sbjct 233 GLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDVDG-------HVMLTDFGLA 285 Query 764 LGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 ++APE + G + A D W G L E+ G+ P Sbjct 286 KEFEENTRSNSMCGTTEYMAPEIVRGKGH--DKAADWWSVGILLYEML-TGKPPFLGSKG 342 Query 821 SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 ++ + + +LP+ + L L EP +R Sbjct 343 KIQQKIVKDKIKLPQFLSNEAHALLKGLLQKEPERR 378 >sp|Q94C40|CIPKH_ARATH CBL-interacting serine/threonine-protein kinase 17 OS=Arabidopsis thaliana OX=3702 GN=CIPK17 PE=1 SV=1 Length=432 Score = 216 bits (550), Expect = 4e-60, Method: Composition-based stats. Identities = 70/262 (27%), Positives = 110/262 (42%), Gaps = 27/262 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW--KQEIDILRTLYHEHI 959 LGEG+ KV + TGE A+K ++ C + + K+EI L+ L H +I Sbjct 16 TLGEGNSAKVKF----AIDTLTGESFAIKIIEKSCITRLNVSFQIKREIRTLKVLKHPNI 71 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 ++ + + + +V+E V G L D + + + Q QQ+ +G++Y H + Sbjct 72 VRLHEVLASKTK--IYMVLECVTGGDLFDRIVSKGKLSETQGRKMFQQLIDGVSYCHNKG 129 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL NVLLD +KI DFGL+ E + SP + APE L + Sbjct 130 VFHRDLKLENVLLDAKGHIKITDFGLSALSQHYREDGLLHTTCGSPN-YVAPEVLANEGY 188 Query 1079 Y-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 ASD+WS GV LY +LT C + + + +G+ P P Sbjct 189 DGAASDIWSCGVILYVILTGCLPFDDA---------------NLAVICRKIFKGD-PPIP 232 Query 1138 DKCPCEVYHLMKNCWETEASFR 1159 ++K + R Sbjct 233 RWISLGAKTMIKRMLDPNPVTR 254 Score = 162 bits (410), Expect = 1e-41, Method: Composition-based stats. Identities = 54/304 (18%), Positives = 96/304 (32%), Gaps = 19/304 (6%) Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYET 658 V +G RV + + D +K+++ S +++ Sbjct 1 MVIKGM-RVGKYELGRTLGEGNSAKVKFAIDTLTGESFAIKIIEKSCITRLNVSFQIKRE 59 Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQL 718 + + H ++ +H V + MV E V G L + +G + + QQL Sbjct 60 IRTLKVLKHPNIVRLHEVLASKTKIYMVLECVTGGDLFDRI-VSKGKLSETQGRKMFQQL 118 Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV-GLGALSRE-----ER 772 +SY NK + H ++ N+LL G IK++D G+ L RE Sbjct 119 IDGVSYCHNKGVFHRDLKLENVLLDAKG-------HIKITDFGLSALSQHYREDGLLHTT 171 Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832 ++APE L A D W G L I + ++ Sbjct 172 CGSPNYVAPEVLANEGYD-GAASDIWSCGVILYVILTGCLPFDDANLAVICRKIFKGDPP 230 Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVF 892 +P T+ + L P R + I + ++ + + Sbjct 231 IPRWISLGAKTMIKRMLDPNPVTRVTIAGIKAHDWFKHDYTPSNYDDDDDVYLIQEDVFM 290 Query 893 HKRY 896 K Y Sbjct 291 MKEY 294 >sp|P93604|LRK10_WHEAT Rust resistance kinase Lr10 OS=Triticum aestivum OX=4565 GN=LRK10 PE=2 SV=1 Length=636 Score = 222 bits (565), Expect = 4e-60, Method: Composition-based stats. Identities = 70/330 (21%), Positives = 122/330 (37%), Gaps = 23/330 (7%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 + + K + +G+G FG V G VA Sbjct 311 HMKVEMFLKTYGTSKPTRYTFSEVKKMARRFKEKVGQGGFGSVYKGEL-----PNGVPVA 365 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 VK L+ G + E+ + ++H +I++ G C + ++ L+ E++P SL Sbjct 366 VKMLENSTGEG--ESFINEVATIGLIHHANIVRLLGFCSEGMRRA--LIYEFMPNESLEK 421 Query 989 YLP-------RHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVK 1038 Y+ ++ + +LL A I GM YLH Q +H D+ N+LLD + K Sbjct 422 YIFSDDSNIFQNLLVPEKLLDIALGIARGMEYLHQGCNQRILHFDIKPHNILLDYNFNPK 481 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE--YKFYYASDVWSFGVTLYELLT 1096 I DFGLAK + + + APE Y +DV+SFG+ + E+++ Sbjct 482 ISDFGLAKLCARDQSIVTL-TAARGTMGYIAPELYSRNFGGVSYKADVYSFGMLVLEMVS 540 Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156 +S ++ V+ EL E ++ + C + Sbjct 541 GRRNSDPRIGSQDDVYLPEWIYEKVINGEELALTLETTQEEKDKVRQLAMVALWCIQWNP 600 Query 1157 SFRPTFENLIPILK-TVHEKYQGQAPSVFS 1185 RP+ ++ +L + P V S Sbjct 601 RNRPSMTKVVNMLTGRLQSLQMPPKPFVSS 630 Score = 204 bits (518), Expect = 5e-54, Method: Composition-based stats. Identities = 52/316 (16%), Positives = 110/316 (35%), Gaps = 63/316 (20%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 +F V + +GQG +VY+G L + V Sbjct 330 TFSEVKKMARRFKEKVGQGGFGSVYKGELPNG-------------------------VPV 364 Query 640 VLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +K+L+ S + +F + + + H ++ + G C G ++ E++ + L+ ++ Sbjct 365 AVKMLENSTGEG-ESFINEVATIGLIHHANIVRLLGFCSEGMRRALIYEFMPNESLEKYI 423 Query 700 RRERGH-----VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGT 751 + + + + +A +A + YL N+ ++H ++ NILL Sbjct 424 FSDDSNIFQNLLVPEKLLDIALGIARGMEYLHQGCNQRILHFDIKPHNILLD-------Y 476 Query 752 SPFIKLSDPGVGLGALSREERV------ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + K+SD G+ + V + ++APE +S D + FG +L Sbjct 477 NFNPKISDFGLAKLCARDQSIVTLTAARGTMGYIAPELYSRNFGGVSYKADVYSFGMLVL 536 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRL----------------PEPSCPQLATLTSQCL 849 E+ + + + + + QLA + C+ Sbjct 537 EMVSGRRNSDPRIGSQDDVYLPEWIYEKVINGEELALTLETTQEEKDKVRQLAMVALWCI 596 Query 850 TYEPTQRPSFRTILRD 865 + P RPS ++ Sbjct 597 QWNPRNRPSMTKVVNM 612 >sp|Q6YY75|NEK6_ORYSJ Serine/threonine-protein kinase Nek6 OS=Oryza sativa subsp. japonica OX=39947 GN=NEK6 PE=1 SV=2 Length=534 Score = 219 bits (558), Expect = 4e-60, Method: Composition-based stats. Identities = 60/299 (20%), Positives = 118/299 (39%), Gaps = 31/299 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILR 952 + + +G G +G L + +K ++ + + + QE+ ++ Sbjct 1 MEQYEVVEQIGRGAYGSAYLVVHKGERKR----YVMKKIRLSKQNDKFQRTAYQEMSLMA 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICE 1009 +L + +I++YK D+G + +V Y G + + + + ++ + Q+ Sbjct 57 SLSNPYIVEYKDGWVDEGTSA-CIVTSYCEGGDMAERIKKARGVLFSEERVCRWFTQLLL 115 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + YLH +HRDL N+LL D +++ DFGLAK + E + + Sbjct 116 ALDYLHCNRVLHRDLKCSNILLTKDNNIRLADFGLAKLLMED-----LASTIVGTPNYMC 170 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE L + + Y SD+WS G ++E+L H + ++ + L + Sbjct 171 PEILADIPYGYKSDIWSLGCCMFEILAHRPAFKAA---------------DMASLINKIN 215 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAPSVFSV 1186 R P P + ++K+ RPT L+ P L+ + +P V Sbjct 216 RSSISPMPPIYSSSLKQIVKSMLRKNPEHRPTAGELLRHPYLQPYLAESCSCSPIYLPV 274 Score = 155 bits (393), Expect = 1e-38, Method: Composition-based stats. Identities = 55/303 (18%), Positives = 98/303 (32%), Gaps = 38/303 (13%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VL 644 ++ + +G+G + Y + E ++ V+ K L Sbjct 1 MEQYEVVEQIGRGAYGSAYLVVHKGE-----------------------RKRYVMKKIRL 37 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVH-GVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + Y+ SLM+ +S+ ++ G G +VT Y E G + +++ R Sbjct 38 SKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSACIVTSYCEGGDMAERIKKAR 97 Query 704 GHV-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 G + QL AL YL ++H ++ NILL + I+L+D G+ Sbjct 98 GVLFSEERVCRWFTQLLLALDYLHCNRVLHRDLKCSNILLTKDN-------NIRLADFGL 150 Query 763 GLGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 + V ++ PE L D W G + EI A + Sbjct 151 AKLLMEDLASTIVGTPNYMCPEILADIPYGY--KSDIWSLGCCMFEILAHRPAFKAADMA 208 Query 821 SEKEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 S + +P L + L P RP+ +LR + + Sbjct 209 SLINKINRSSISPMPPIYSSSLKQIVKSMLRKNPEHRPTAGELLRHPYLQPYLAESCSCS 268 Query 880 VNP 882 Sbjct 269 PIY 271 >sp|Q924U5|TESK2_RAT Dual specificity testis-specific protein kinase 2 OS=Rattus norvegicus OX=10116 GN=Tesk2 PE=2 SV=1 Length=570 Score = 220 bits (560), Expect = 4e-60, Method: Composition-based stats. Identities = 72/286 (25%), Positives = 126/286 (44%), Gaps = 33/286 (12%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G G F +V + + +G+++A+K + +R+ +E+ ++ L H Sbjct 59 FTREKIGSGFFSEV----FKVRHRASGQVMALKM---NTLSSNRANLLKEMQLMNRLSHP 111 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHA 1016 +I+++ G C QG+ L + EY+ G+L L + + + A I G++YLH Sbjct 112 NILRFMGVCVHQGQ--LHALTEYINSGNLEQLLDSNLYLPWTVRVKLAYDIAVGLSYLHF 169 Query 1017 QHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + HRDL ++N L+ D + DFGLA+ +P+ SP FW APE L Sbjct 170 KGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGSEKLAVVGSP-FWMAPEVL 228 Query 1074 KEYKFYYASDVWSFGVTLYELLTH--CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 ++ + +DV+S+G+ L E++ D P T+ L A M Sbjct 229 RDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVG---------- 278 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 CP + L NC + RP+FE + L+ + + Q Sbjct 279 -------DCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLEEIMSRLQ 317 Score = 192 bits (487), Expect = 2e-50, Method: Composition-based stats. Identities = 65/314 (21%), Positives = 116/314 (37%), Gaps = 40/314 (13%) Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 ++ R S + +F R+ + +G G + V++ R R Sbjct 33 VQVGRVSSSSYRAIISAFSRLTSLDDFTREKIGSGFFSEVFKVRHRA------------- 79 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 GQ + + + L + ++ + LM+++SH ++ GVCV + Sbjct 80 ---------SGQVMALKMNTLSSNRANL----LKEMQLMNRLSHPNILRFMGVCVHQGQL 126 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 +TEY+ G L+ L ++P ++ +A +A LSYL K + H ++ +N L+ Sbjct 127 HALTEYINSGNLEQLL-DSNLYLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIK 185 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDK 797 R + ++D G+ V W+APE L + D Sbjct 186 R----DENGYSAVVADFGLAEKIPDASIGSEKLAVVGSPFWMAPEVLRD--EPYNEKADV 239 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQR 856 + +G L EI +A +E + CP LT C +P R Sbjct 240 FSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPSDFLQLTFNCCNMDPKLR 299 Query 857 PSFRTILRDLTRLQ 870 PSF I + L + Sbjct 300 PSFEEIGKTLEEIM 313 >sp|Q2WFL5|HOG1_COCMI Mitogen-activated protein kinase HOG1 OS=Cochliobolus miyabeanus OX=101162 GN=HOG1 PE=3 SV=1 Length=354 Score = 213 bits (543), Expect = 4e-60, Method: Composition-based stats. Identities = 67/274 (24%), Positives = 107/274 (39%), Gaps = 29/274 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V + T + VAVK + K P +E+ +L+ L HE+II Sbjct 26 VGMGAFGLVC----SAKDQLTNQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENIIS 81 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 E + V E + L L + + F QI G+ Y+H+ +H Sbjct 82 LSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVH 139 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKFYY 1080 RDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 140 RDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKYDV 193 Query 1081 ASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTELL 1128 D+WS G E+L + + EL+G + LR + L Sbjct 194 EVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVQSL 253 Query 1129 ERGERLP---RPDKCPCEVYHLMKNCWETEASFR 1159 + ER P + + L++N + R Sbjct 254 PKRERQPLANKFKNAEPDAVDLLENMLVFDPRKR 287 Score = 134 bits (337), Expect = 8e-33, Method: Composition-based stats. Identities = 35/231 (15%), Positives = 74/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + +D+ V +K ++ P ++ Y Sbjct 10 FGTTFEITSRYTDLQLVGMGAF---GLVCSAKDQLTNQAVAVKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q9R1U5|SIK1_RAT Serine/threonine-protein kinase SIK1 OS=Rattus norvegicus OX=10116 GN=Sik1 PE=1 SV=1 Length=776 Score = 224 bits (572), Expect = 4e-60, Method: Composition-based stats. Identities = 65/273 (24%), Positives = 107/273 (39%), Gaps = 29/273 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTL 954 + R LG+G+F V L + T VA+K + K + +E+ +++ L Sbjct 26 FYDVERTLGKGNFAVVKL----ARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLL 81 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAY 1013 H +IIK E + L +V E+ G + DYL + + + QI + Y Sbjct 82 NHPNIIKLYQVMETKD--MLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEY 139 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 H H +HRDL N+LLD + +K+ DFG G + SP + APE Sbjct 140 CHNHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKPGEP---LSTWCGSPP-YAAPEVF 195 Query 1074 KEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + ++ D+WS GV LY L+ P + L + + G Sbjct 196 EGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGP---------------NLPTLRQRVLEG- 239 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 R P + L++ + + R T + Sbjct 240 RFRIPFFMSQDCETLIRRMLVVDPAKRITIAQI 272 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 66/351 (19%), Positives = 115/351 (33%), Gaps = 40/351 (11%) Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620 ++IM A P Q RV ++ LG+G V R RV Sbjct 1 MVIMSEFSAVPTGTGQGQQKPLRVGFYDVE--RTLGKGNFAVVKLARHRV---------- 48 Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCV 678 + +V +K++D + D + Y LM ++H ++ ++ V Sbjct 49 --------------TKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPNIIKLYQVME 94 Query 679 RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGR 738 +VTE+ ++G + +L GH+ Q+ SA+ Y N ++VH ++ Sbjct 95 TKDMLYIVTEFAKNGEMFDYLTSN-GHLSENEARKKFWQILSAVEYCHNHHIVHRDLKTE 153 Query 739 NILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAM 795 N+LL + IKL+D G G P+ APE G + Sbjct 154 NLLLD-------GNMDIKLADFGFGNFYKPGEPLSTWCGSPPYAAPEVFEGKEYE-GPQL 205 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855 D W G L + P+ ++ + + R+P TL + L +P + Sbjct 206 DIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCETLIRRMLVVDPAK 265 Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906 R + I + L + G Sbjct 266 RITIAQIRQHRWMQADPTLLQQDDPAFSMQGYTSNLGDYNEQVLGIMQALG 316 >sp|Q9VXE5|PAKM_DROME Serine/threonine-protein kinase PAK mbt OS=Drosophila melanogaster OX=7227 GN=mbt PE=1 SV=2 Length=639 Score = 222 bits (565), Expect = 4e-60, Method: Composition-based stats. Identities = 64/268 (24%), Positives = 111/268 (41%), Gaps = 23/268 (9%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 +GEG G V + T+ TG VAVK + Q R E+ I+R +H + Sbjct 370 HFNKIGEGSTGTVCI----ATDKSTGRQVAVKKMDLRK-QQRRELLFNEVVIMRDYHHPN 424 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 I++ E L +VMEY+ G+L D + + Q+ +Q + +AYLH+Q Sbjct 425 IVETYSSFLVNDE--LWVVMEYLEGGALTDIVTHSRMDEEQIATVCKQCLKALAYLHSQG 482 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRD+ + ++LL D VK+ DFG V + R+ +W +PE + + Sbjct 483 VIHRDIKSDSILLAADGRVKLSDFGFCAQVSQELP---KRKSLVGTPYWMSPEVISRLPY 539 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 D+WS G+ + E++ + P + R+ ++ + L Sbjct 540 GPEVDIWSLGIMVIEMVDGEPPFFNEP-----------PLQAMRRIRDM--QPPNLKNAH 586 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLI 1166 K + + + + R T L+ Sbjct 587 KVSPRLQSFLDRMLVRDPAQRATAAELL 614 Score = 186 bits (472), Expect = 5e-48, Method: Composition-based stats. Identities = 55/291 (19%), Positives = 103/291 (35%), Gaps = 44/291 (15%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 ++ + + +G+G+ V D+ +V +K + Sbjct 364 PRENLDHFNKIGEGSTGTVC------------------------IATDKSTGRQVAVKKM 399 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D + +M H ++ + + E +V EY+E G L + R Sbjct 400 DLRKQQRRELLFNEVVIMRDYHHPNIVETYSSFLVNDELWVVMEYLEGGALTDIVTHSR- 458 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV-- 762 + V +Q AL+YL ++ ++H ++ +ILLA G +KLSD G Sbjct 459 -MDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLAADGR-------VKLSDFGFCA 510 Query 763 --GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 R+ V W++PE + +D W G ++E+ DGE P + P Sbjct 511 QVSQELPKRKSLVGTPYWMSPEVIS--RLPYGPEVDIWSLGIMVIEMV-DGEPPFFNEPP 567 Query 821 SEKE----HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + + P+L + + L +P QR + +L Sbjct 568 LQAMRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAAELLAHPF 618 >sp|Q8VHJ5|MARK1_MOUSE Serine/threonine-protein kinase MARK1 OS=Mus musculus OX=10090 GN=Mark1 PE=1 SV=2 Length=795 Score = 225 bits (573), Expect = 4e-60, Method: Composition-based stats. Identities = 70/239 (29%), Positives = 106/239 (44%), Gaps = 13/239 (5%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL- 932 ++ ++ H + + +G+G+F KV L + TG VAVK + Sbjct 37 RQNLPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKL----ARHVLTGREVAVKIID 92 Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992 K P +E+ I++ L H +I+K E EK+L LVMEY G + DYL Sbjct 93 KTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIE--TEKTLYLVMEYASGGEVFDYLVA 150 Query 993 H-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 H + + +QI + Y H + +HRDL A N+LLD D +KI DFG + G Sbjct 151 HGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADFGFSNEFTVG 210 Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 ++ + + APE + K+ DVWS GV LY L++ K L Sbjct 211 NKL----DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL 265 Score = 182 bits (461), Expect = 7e-46, Method: Composition-based stats. Identities = 58/320 (18%), Positives = 103/320 (32%), Gaps = 45/320 (14%) Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 P ++S+ + R S + Q +G+G V R + G Sbjct 31 PAKSSSRQNLPRCRNSITSATDEQPHIG-----NYRLQKTIGKGNFAKVKLARHVLTGR- 84 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAF 672 V +K++D + + + +M ++H ++ Sbjct 85 -----------------------EVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 121 Query 673 VHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVH 732 + V +V EY G + +L G + +Q+ SA+ Y K +VH Sbjct 122 LFEVIETEKTLYLVMEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYCHQKCIVH 180 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGAN 789 ++ N+LL IK++D G + P+ APE G Sbjct 181 RDLKAENLLLD-------ADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKY 233 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQC 848 +D W G L + G P ++ E R +R+P L + Sbjct 234 D-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKL 291 Query 849 LTYEPTQRPSFRTILRDLTR 868 L P +R S I++D Sbjct 292 LVLNPIKRGSLEQIMKDRWM 311 >sp|Q6C4M9|HOG1_YARLI Mitogen-activated protein kinase HOG1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) OX=284591 GN=HOG1 PE=3 SV=1 Length=386 Score = 214 bits (546), Expect = 4e-60, Method: Composition-based stats. Identities = 67/303 (22%), Positives = 108/303 (36%), Gaps = 29/303 (10%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQ 939 + + +G G FG V + T + VA+K + K P Sbjct 4 FIRTQIFGTCFEITSRYVDLNPVGMGAFGLVC----SAKDQLTDQNVAIKKIMKPFGTPV 59 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ 999 +E+ +L+ L HE++I E + V E + L L + Sbjct 60 LSKRTYRELKLLKHLRHENLICLSDIFISPLED-IYFVTELL-GTDLHRLLMTRPLEKQF 117 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 + F QI G+ Y+H+ +HRDL N+L++ + +KI DFGLA+ Sbjct 118 IQYFLYQILRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQD------TQMT 171 Query 1060 DGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIG 1113 S ++ APE + K+ D+WS G E+L + EL+G Sbjct 172 GYVSTRYYRAPEIMLTWQKYDVEVDIWSTGCIFAEMLEGKPLFPGKDHVHQFSIITELLG 231 Query 1114 IAQGQM-------TVLRLTELLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFE 1163 + LR L R ER+P + E LM+ + R T Sbjct 232 SPPEDVIHTICSENTLRFVRTLPRRERIPLASKFRNADPEAIDLMEKMLVFDPKKRITAA 291 Query 1164 NLI 1166 + Sbjct 292 EAL 294 Score = 132 bits (332), Expect = 8e-32, Method: Composition-based stats. Identities = 53/340 (16%), Positives = 103/340 (30%), Gaps = 49/340 (14%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + +D+ + V +K ++ P ++ Y Sbjct 10 FGTCFEITSRYVDLNPVGMGAF---GLVCSAKDQLTDQNVAIKKIMKPFGTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H +L + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENLICLSDIFISPLEDIYFVTELL-GTDLHRLLMTR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDTQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEI-----CFDGEAPLQSRS---------PS 821 + APE + +D W G E+ F G+ + S P Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSTGCIFAEMLEGKPLFPGKDHVHQFSIITELLGSPPE 235 Query 822 EKEHFYQ------------RQHRLP-----EPSCPQLATLTSQCLTYEPTQRPSFRTILR 864 + H R+ R+P + P+ L + L ++P +R + L Sbjct 236 DVIHTICSENTLRFVRTLPRRERIPLASKFRNADPEAIDLMEKMLVFDPKKRITAAEALA 295 Query 865 DLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 H+ +D S K+ Sbjct 296 HPYLAPYHDPSDEPVAEERFDWSFNDADLPVDTWKVMMYS 335 >sp|Q96S53|TESK2_HUMAN Dual specificity testis-specific protein kinase 2 OS=Homo sapiens OX=9606 GN=TESK2 PE=1 SV=1 Length=571 Score = 220 bits (560), Expect = 4e-60, Method: Composition-based stats. Identities = 72/306 (24%), Positives = 130/306 (42%), Gaps = 33/306 (11%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 + + S + + +G G F +V + + +G+++A+K + Sbjct 39 WPSSYRALISAFSRLTRLDDFTCEKIGSGFFSEV----FKVRHRASGQVMALKM---NTL 91 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIG 996 +R+ +E+ ++ L H +I+++ G C QG+ L + EY+ G+L L + + Sbjct 92 SSNRANMLKEVQLMNRLSHPNILRFMGVCVHQGQ--LHALTEYINSGNLEQLLDSNLHLP 149 Query 997 LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHE 1053 + A I G++YLH + HRDL ++N L+ D + DFGLA+ +P+ Sbjct 150 WTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDVSM 209 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH--CDSSQSPPTKFLEL 1111 SP FW APE L++ + +DV+S+G+ L E++ D P T+ L Sbjct 210 GSEKLAVVGSP-FWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGL 268 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 A M CP + L NC + RP+F + L+ Sbjct 269 DYDAFQHMVG-----------------DCPPDFLQLTFNCCNMDPKLRPSFVEIGKTLEE 311 Query 1172 VHEKYQ 1177 + + Q Sbjct 312 ILSRLQ 317 Score = 197 bits (500), Expect = 3e-52, Method: Composition-based stats. Identities = 66/314 (21%), Positives = 117/314 (37%), Gaps = 40/314 (13%) Query 563 IMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMD 622 + + R P + +F R+ + + +G G + V++ R R Sbjct 32 VSQVGRVWPSSYRALISAFSRLTRLDDFTCEKIGSGFFSEVFKVRHRA------------ 79 Query 623 DEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 GQ + + + L + ++ + LM+++SH ++ GVCV + Sbjct 80 ----------SGQVMALKMNTLSSNRANM----LKEVQLMNRLSHPNILRFMGVCVHQGQ 125 Query 683 NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +TEY+ G L+ L H+P ++ +A +A LSYL K + H ++ +N L+ Sbjct 126 LHALTEYINSGNLEQLL-DSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLI 184 Query 743 ARLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMD 796 R + ++D G+ V W+APE L + D Sbjct 185 KR----DENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRD--EPYNEKAD 238 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ-LATLTSQCLTYEPTQ 855 + +G L EI +A +E + CP LT C +P Sbjct 239 VFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKL 298 Query 856 RPSFRTILRDLTRL 869 RPSF I + L + Sbjct 299 RPSFVEIGKTLEEI 312 >sp|P51954|NEK1_MOUSE Serine/threonine-protein kinase Nek1 OS=Mus musculus OX=10090 GN=Nek1 PE=1 SV=2 Length=1203 Score = 229 bits (584), Expect = 5e-60, Method: Composition-based stats. Identities = 64/278 (23%), Positives = 121/278 (44%), Gaps = 28/278 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILR 952 +++ +GEG FGK L + G +K + + + R ++E+ +L Sbjct 1 MEKYVRLQKIGEGSFGKAVLV----KSTEDGRHYVIKEINISRMSDKERQESRREVAVLA 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICE 1009 + H +I++YK E+ G SL +VM+Y G L + Q+L + QIC Sbjct 57 NMKHPNIVQYKESFEENG--SLYIVMDYCEGGDLFKRINAQKGALFQEDQILDWFVQICL 114 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + ++H + +HRD+ ++N+ L D V++GDFG+A+ + E R ++ + Sbjct 115 ALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELART---CIGTPYYLS 171 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE + + SD+W+ G LYEL T + ++ K L L + Sbjct 172 PEICENKPYNNKSDIWALGCVLYELCTLKHAFEAGNMKNLVL---------------KII 216 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 G P ++ L+ ++ RP+ +++ Sbjct 217 SGSFPPVSPHYSYDLRSLLSQLFKRNPRDRPSVNSILE 254 Score = 160 bits (405), Expect = 2e-38, Method: Composition-based stats. Identities = 44/283 (16%), Positives = 91/283 (32%), Gaps = 37/283 (13%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ +L +G+G+ LV + G+ + + Sbjct 1 MEKYVRLQKIGEGSFGK----------------------AVLVKSTEDGRHYVIKEINIS 38 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 ++++ + H ++ +V +Y E G L + ++G Sbjct 39 RMSDKERQESRREVAVLANMKHPNIVQYKESFEENGSLYIVMDYCEGGDLFKRINAQKGA 98 Query 706 V-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + Q+ AL ++ ++ ++H ++ +NI L + G ++L D G+ Sbjct 99 LFQEDQILDWFVQICLALKHVHDRKILHRDIKSQNIFLTKDG-------TVQLGDFGIAR 151 Query 765 GALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS-RS 819 S + +L+PE + D W G L E+C A Sbjct 152 VLNSTVELARTCIGTPYYLSPEICEN--KPYNNKSDIWALGCVLYELCTLKHAFEAGNMK 209 Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 + + L +L SQ P RPS +I Sbjct 210 NLVLKIISGSFPPVSPHYSYDLRSLLSQLFKRNPRDRPSVNSI 252 >sp|Q42371|ERECT_ARATH LRR receptor-like serine/threonine-protein kinase ERECTA OS=Arabidopsis thaliana OX=3702 GN=ERECTA PE=1 SV=1 Length=976 Score = 227 bits (579), Expect = 5e-60, Method: Composition-based stats. Identities = 72/337 (21%), Positives = 130/337 (39%), Gaps = 25/337 (7%) Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 L L + C P P F D +L +N + + L + Sbjct 595 LMVLIAAC---RPHNPPPFLDGSLDKPVTYSTPKLVILHMNMALHVYEDIMRMTENLSEK 651 Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G V + VA+K L + PQ ++ E+++L ++ H +++ Sbjct 652 YIIGHGASSTVYKCVLKNC-----KPVAIKRLYSH-NPQSMKQFETELEMLSSIKHRNLV 705 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLH- 1015 + L +Y+ GSL D L + ++ L A +G+AYLH Sbjct 706 SLQAYSLSHLGS--LLFYDYLENGSLWDLLHGPTKKKTLDWDTRLKIAYGAAQGLAYLHH 763 Query 1016 --AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + IHRD+ + N+LLD D ++ DFG+AK++ + + + PE Sbjct 764 DCSPRIIHRDVKSSNILLDKDLEARLTDFGIAKSLCVSKSH--TSTYVMGTIGYIDPEYA 821 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + + SDV+S+G+ L ELLT + L + + + E+ + Sbjct 822 RTSRLTEKSDVYSYGIVLLELLTRRKAVDD----ESNLHHLIMSKTGNNEVMEMADPDIT 877 Query 1134 LPRPD-KCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 D +V+ L C + + + RPT + +L Sbjct 878 STCKDLGVVKKVFQLALLCTKRQPNDRPTMHQVTRVL 914 Score = 188 bits (478), Expect = 2e-47, Method: Composition-based stats. Identities = 60/360 (17%), Positives = 118/360 (33%), Gaps = 68/360 (19%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + +++ +G G + VY+ L+ V +K L Sbjct 645 TENLSEKYIIGHGASSTVYKCVLKNCKP-------------------------VAIKRLY 679 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + F ++S + H +L + + +++ +Y+E+G L L Sbjct 680 SHNPQSMKQFETELEMLSSIKHRNLVSLQAYSLSHLGSLLFYDYLENGSLWDLLHGPTKK 739 Query 706 VPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + W ++ +A A L+YL + ++H +V NILL + A +L+D Sbjct 740 KTLDWDTRLKIAYGAAQGLAYLHHDCSPRIIHRDVKSSNILLDKDLEA-------RLTDF 792 Query 761 GVGLG-----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ + + + I ++ PE + L+ D + +G LLE+ +A Sbjct 793 GIAKSLCVSKSHTSTYVMGTIGYIDPEYART--SRLTEKSDVYSYGIVLLELLTRRKAVD 850 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLAT-------------LTSQCLTYEPTQRPSFRTI 862 + + + E + P + + L C +P RP+ + Sbjct 851 DESNLHHLIMSKTGNNEVMEMADPDITSTCKDLGVVKKVFQLALLCTKRQPNDRPTMHQV 910 Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH-----------FGKV 911 R L T + A V LK + FG+V Sbjct 911 TRVLGSFMLSEQPPAATDTSATLAGSCYVDEYANLKTPHSVNCSSMSASDAQLFLRFGQV 970 >sp|O14047|PPK11_SCHPO Serine/threonine-protein kinase ppk11 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ppk11 PE=3 SV=1 Length=312 Score = 212 bits (539), Expect = 5e-60, Method: Composition-based stats. Identities = 76/290 (26%), Positives = 118/290 (41%), Gaps = 26/290 (9%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDIL 951 K + ++ +G+G FG V + + + ++VA+K + D QEI+ L Sbjct 1 MEKHQYRDLQLIGQGSFGSV----FRAQDVESSKIVALKVVDLDATKDQIETLTQEINFL 56 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEG 1010 L HI KY D L + MEY GS D L + + +Q+ E Sbjct 57 IDLNSVHITKYYASFVDGF--RLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEA 114 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 + YLH Q +HRD+ A N+L D LVK+ DFG++ + + +D FW AP Sbjct 115 LVYLHGQGKMHRDIKAANILTMKDGLVKLADFGVSGQLESLRDKN---DDFVGTPFWMAP 171 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E +K+ + Y +D+WS G+T YEL T + S L+ I + L ++ Sbjct 172 EVVKQTGYNYKADIWSLGITAYELATG-EPPYSGIHPMKVLLLIPKHSPPSLERSKF--- 227 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180 + NC + R T E L +KY Sbjct 228 ----------SRAFCDFVSNCLKKNPKDRATAEYLSKH--KFIKKYCPNT 265 Score = 172 bits (436), Expect = 3e-46, Method: Composition-based stats. Identities = 63/347 (18%), Positives = 107/347 (31%), Gaps = 52/347 (15%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 +++ + L +GQG+ +V+ + D V LKV Sbjct 1 MEKHQYRDLQLIGQGSFGSVFRAQ------------------------DVESSKIVALKV 36 Query 644 LD-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 +D + D + + + ++ H+ + V G + EY + G L+ Sbjct 37 VDLDATKDQIETLTQEINFLIDLNSVHITKYYASFVDGFRLWITMEYCDGGSCLDLLKLS 96 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 G V +Q+ AL YL + +H ++ NIL + GL +KL+D GV Sbjct 97 -GTFSERVIAEVMRQVLEALVYLHGQGKMHRDIKAANILTMKDGL-------VKLADFGV 148 Query 763 GLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 S ++ V W+APE + + D W G T E+ GE P Sbjct 149 SGQLESLRDKNDDFVGTPFWMAPEVVKQTGYNY--KADIWSLGITAYELA-TGEPPYSGI 205 Query 819 SPSEKEHFYQRQHRLP---EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 P + + S CL P R + + + + Sbjct 206 HPMKVLLLIPKHSPPSLERSKFSRAFCDFVSNCLKKNPKDRATAEYLSKHKFIKKYCPNT 265 Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH---------FGKVSL 913 V V + +G FG V Sbjct 266 SVKEVVASYAKWKESELLPEATPYNSTMGNSANTIDEVVWDFGTVRR 312 >sp|Q17833|OLD1_CAEEL Tyrosine-protein kinase receptor old-1 OS=Caenorhabditis elegans OX=6239 GN=old-1 PE=2 SV=3 Length=502 Score = 218 bits (555), Expect = 5e-60, Method: Composition-based stats. Identities = 90/314 (29%), Positives = 132/314 (42%), Gaps = 30/314 (10%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM-----VAVKALKA 934 + A + K R LG G FG + N E VAVK Sbjct 158 MYLHYYAEVEINEEDLDISKGRPLGSGEFGIIRKGFLRSKNSKNEEKESRLEVAVKLPLN 217 Query 935 DCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993 + + E+ ++ + H +I+ G K +V E+V G L +L + Sbjct 218 EYNQIQQELIYDELKVMCAVGKHPNILALVGGITFGERK--MIVSEFVENGDLLSFLRDN 275 Query 994 ----------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037 S+ L LL FA QI +GM YL +HRDLA RNVL+ +R++ Sbjct 276 RIYFTNDQWTLETEQDSLSLVDLLSFAFQIAKGMEYLIHVPCVHRDLALRNVLIKKNRII 335 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 +I DFGLA+ Y D P+ W APE + + F SDVWS+GV LYEL + Sbjct 336 RIADFGLARRHKNKDYYKTQSVDTPLPIHWMAPESIDKLLFTQKSDVWSYGVCLYELFSL 395 Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157 S + +I Q + L G+RL +P E+Y++MK CW+ + + Sbjct 396 GKSP------YENVIKYDQRDFYWKYVLSYLNEGKRLAQPAHADAEIYNVMKLCWDLDMN 449 Query 1158 FRPTFENLIPILKT 1171 R TF + I + Sbjct 450 SRTTFLDCIEFFEK 463 Score = 189 bits (480), Expect = 4e-50, Method: Composition-based stats. Identities = 60/312 (19%), Positives = 121/312 (39%), Gaps = 57/312 (18%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV-LDP 646 +I++ LG G + +G LR + S ++ L V +K+ L+ Sbjct 174 DISKGRPLGSGEFGIIRKGFLRSKNS---------------KNEEKESRLEVAVKLPLNE 218 Query 647 SHHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-- 703 + Y+ +M V H ++ + G G ++V+E+VE+G L +LR R Sbjct 219 YNQIQQELIYDELKVMCAVGKHPNILALVGGITFGERKMIVSEFVENGDLLSFLRDNRIY 278 Query 704 ------------GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 + + + A Q+A + YL + VH ++ RN+L+ + Sbjct 279 FTNDQWTLETEQDSLSLVDLLSFAFQIAKGMEYLIHVPCVHRDLALRNVLIKK------- 331 Query 752 SPFIKLSDPGVGLGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATL 804 + I+++D G+ +++ I W+APE + + D W +G L Sbjct 332 NRIIRIADFGLARRHKNKDYYKTQSVDTPLPIHWMAPESIDKLL--FTQKSDVWSYGVCL 389 Query 805 LEICFDGEAPLQSRSPSEKEHFYQR--------QHRL--PEPSCPQLATLTSQCLTYEPT 854 E+ G++P ++ ++ FY + RL P + ++ + C + Sbjct 390 YELFSLGKSPYENVIKYDQRDFYWKYVLSYLNEGKRLAQPAHADAEIYNVMKLCWDLDMN 449 Query 855 QRPSFRTILRDL 866 R +F + Sbjct 450 SRTTFLDCIEFF 461 >sp|Q4W6D3|HOG1_COCHE Mitogen-activated protein kinase HOG1 OS=Cochliobolus heterostrophus OX=5016 GN=HOG1 PE=1 SV=1 Length=355 Score = 213 bits (543), Expect = 5e-60, Method: Composition-based stats. Identities = 67/276 (24%), Positives = 108/276 (39%), Gaps = 29/276 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VAVK + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SAKDQLTNQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVQ 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFR 1159 L + ER P + + L++N + R Sbjct 252 SLPKRERQPLANKFKNAEPDAVDLLENMLVFDPRKR 287 Score = 134 bits (338), Expect = 7e-33, Method: Composition-based stats. Identities = 34/213 (16%), Positives = 69/213 (32%), Gaps = 18/213 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + +D+ V +K ++ P ++ Y Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSAKDQLTNQAVAVKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + APE + +D W G E+ Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML 208 >sp|Q01887|RYK_MOUSE Tyrosine-protein kinase RYK OS=Mus musculus OX=10090 GN=Ryk PE=1 SV=2 Length=594 Score = 220 bits (561), Expect = 5e-60, Method: Composition-based stats. Identities = 86/282 (30%), Positives = 135/282 (48%), Gaps = 28/282 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEM--VAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 L EG FG++ D E VK +K + E LR L+H +++ Sbjct 323 LQEGTFGRIFHGILVDEKDPNKEKQTF-VKTVKDQASEVQVTMMLTESCKLRGLHHRNLL 381 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQLLLFAQQICEGM 1011 C ++GEK + +V+ Y+ G+L+ +L + +I L+ A QI GM Sbjct 382 PITHVCIEEGEKPM-VVLPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGM 440 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 +YL + IHRDLAARN ++D+ VKI D L++ + +Y+ + ++ + PV W A E Sbjct 441 SYLARREVIHRDLAARNCVIDDTLQVKITDNALSRDLFP-MDYHCLGDNENRPVRWMALE 499 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 L +F ASDVW+FGVTL+EL+T L + + L+ G Sbjct 500 SLVNNEFSSASDVWAFGVTLWELMT--------------LGQTPYVDIDPFEMAAYLKDG 545 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 R+ +P CP E++ +M CW + RP F+ L+ L H Sbjct 546 YRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFH 587 Score = 192 bits (489), Expect = 1e-50, Method: Composition-based stats. Identities = 65/334 (19%), Positives = 135/334 (40%), Gaps = 49/334 (15%) Query 558 TSNLIIMRGARASPRTLNL----SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 +S +R + R++ L +++ + ++ IT L +GT ++ G L Sbjct 282 SSGYPTLRIEKNDLRSVTLLEAKAKVKDIAISRERITLKDVLQEGTFGRIFHGIL----- 336 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF-YETASLMSQVSHTHLAF 672 V +D +E + +K + ++ + + + + H +L Sbjct 337 --------------VDEKDPNKEKQTFVKTVKDQASEVQVTMMLTESCKLRGLHHRNLLP 382 Query 673 VHGVCVR-GPENIMVTEYVEHGPLDVWLR-------RERGHVPMAWKMVVAQQLASALSY 724 + VC+ G + ++V Y+ G L ++LR + + +A Q+A +SY Sbjct 383 ITHVCIEEGEKPMVVLPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSY 442 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV------ERIPW 778 L + ++H ++ RN ++ + +K++D + + + W Sbjct 443 LARREVIHRDLAARNCVID-------DTLQVKITDNALSRDLFPMDYHCLGDNENRPVRW 495 Query 779 LAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEP 836 +A E L N S+A D W FG TL E+ G+ P P E + + +R+ P Sbjct 496 MALESLVN--NEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPIN 553 Query 837 SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 +L + + C +P +RP F+ +++ LT Sbjct 554 CPDELFAVMACCWALDPEERPKFQQLVQCLTEFH 587 >sp|A0A075F7E9|LERK1_ORYSI G-type lectin S-receptor-like serine/threonine-protein kinase LECRK1 OS=Oryza sativa subsp. indica OX=39946 GN=LECRK1 PE=1 SV=2 Length=813 Score = 225 bits (573), Expect = 5e-60, Method: Composition-based stats. Identities = 67/274 (24%), Positives = 113/274 (41%), Gaps = 14/274 (5%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G G V + D +AVK + P+ + E++ + +H+++++ Sbjct 529 LGAGASGVVYKGQLE---DELKTNIAVKTIHK-LQPETEKEFMVEVETIGQTFHKNLVRL 584 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH---AQH 1018 G C ++ E+ LV E++ G L L +S + A + G YLH ++ Sbjct 585 LGFCNERAER--LLVYEFMTNGPLNRLLFDNSRPHWNTRVHIALGVARGFLYLHDECSKQ 642 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IH D+ +N+LLD++ + KI DFGLAK + R + + APE K Sbjct 643 IIHCDIKPQNILLDDNLVAKISDFGLAKLLLTNQT--RTKTGIRGTRGYVAPEWFKNIGI 700 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELI--GIAQGQMTVLRLTELLERGERLPR 1136 DV+SFGV L EL+ + + + I A R+ L+E + Sbjct 701 STKVDVYSFGVILLELVCCRRNVELEVVDEEQTIVTYWANDCYRSGRIDLLVEGDDEAIY 760 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 K + C + + S RP + +L Sbjct 761 DIKKVERFVTVALWCLQEDPSMRPNMLKVTQMLD 794 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 62/334 (19%), Positives = 118/334 (35%), Gaps = 61/334 (18%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 N+ + + + S L L ++ +++ LG G VY+G+L E + Sbjct 494 KKNIPLSQASSKSQ--LPLKTFTYKELEKATAGFHEILGAGASGVVYKGQLEDELKTN-- 549 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 + +K + + F + Q H +L + G C Sbjct 550 ---------------------IAVKTIHKLQPETEKEFMVEVETIGQTFHKNLVRLLGFC 588 Query 678 VRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGN 734 E ++V E++ +GPL+ L ++ +A +A YL +K ++H + Sbjct 589 NERAERLLVYEFMTNGPLNRLLFDN-SRPHWNTRVHIALGVARGFLYLHDECSKQIIHCD 647 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGAN 789 + +NILL + K+SD G+ L+ + R ++APE Sbjct 648 IKPQNILLD-------DNLVAKISDFGLAKLLLTNQTRTKTGIRGTRGYVAPEWFKNIG- 699 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK------EHFYQRQHRL---------- 833 +ST +D + FG LLE+ E+ + R R+ Sbjct 700 -ISTKVDVYSFGVILLELVCCRRNVELEVVDEEQTIVTYWANDCYRSGRIDLLVEGDDEA 758 Query 834 --PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + T+ CL +P+ RP+ + + Sbjct 759 IYDIKKVERFVTVALWCLQEDPSMRPNMLKVTQM 792 >sp|M1T7M3|HOG1B_WALI9 Mitogen-activated protein kinase HOG1B OS=Wallemia ichthyophaga (strain EXF-994 / CBS 113033) OX=1299270 GN=HOG1B PE=1 SV=1 Length=368 Score = 214 bits (544), Expect = 5e-60, Method: Composition-based stats. Identities = 66/281 (23%), Positives = 108/281 (38%), Gaps = 29/281 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V + T VA+K + K P +E+ +L+ + HE+II Sbjct 26 VGMGAFGLVC----SAKDQLTSSPVAIKKIMKPFSTPVLSKRTYRELKLLKHIRHENIIS 81 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 E + V E + L L + + F QI G+ Y+H+ +H Sbjct 82 LSDIFISPSED-IYFVTELL-GTDLHRLLTARPLEKQFIQYFLYQILRGLKYVHSAGVVH 139 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKFYY 1080 RDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 140 RDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKYDV 193 Query 1081 ASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTELL 1128 A D+WS G E+L + + EL+G + LR + L Sbjct 194 AVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVQSL 253 Query 1129 ERGERLPRPDKC---PCEVYHLMKNCWETEASFRPTFENLI 1166 + R+P +K L++ + R T + Sbjct 254 PKKPRIPFNEKFKTNDPLALDLVEKMLSFDPRTRITASQAL 294 Score = 131 bits (330), Expect = 1e-31, Method: Composition-based stats. Identities = 36/231 (16%), Positives = 76/231 (33%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +++ R G + +D+ V +K ++ P ++ Y Sbjct 10 FGTLFQITSRYVNLEPVGMGAF---GLVCSAKDQLTSSPVAIKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRGPE-NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + E VTE + L L + + Sbjct 67 ELKLLKHIRHENIISLSDIFISPSEDIYFVTELL-GTDLHRLLTAR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + A+D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVAVDIWSTGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q9LQQ9|MPK13_ARATH Mitogen-activated protein kinase 13 OS=Arabidopsis thaliana OX=3702 GN=MPK13 PE=1 SV=1 Length=363 Score = 213 bits (543), Expect = 5e-60, Method: Composition-based stats. Identities = 75/332 (23%), Positives = 132/332 (40%), Gaps = 35/332 (11%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCG 937 + + +Y+ I +G G +G V TN T E VA+K + A Sbjct 15 RYVMYNVLGNIFELSSKYIPPIEPIGRGAYGIVCC----ATNSETNEEVAIKKIANAFDN 70 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL---QLVMEYVPLGSLRDYLPR-H 993 +EI +L + H+++IK K E ++ +V E + L + Sbjct 71 RVDAKRTLREIKLLSHMDHDNVIKIKDIIELPEKERFEDVYIVYELMD-TDLHQIIRSTQ 129 Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 ++ F QI G+ Y+H+ + +HRDL N++L+ + +KI DFGLA+ E Sbjct 130 TLTDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLVLNTNCDLKICDFGLARTSNETE- 188 Query 1054 YYRVREDGDSPVFWYAPE-CLKEYKFYYASDVWSFGVTLYELLTHCDSSQ---------- 1102 + + ++ APE L ++ A D+WS G E+L Sbjct 189 ---IMTEYVVTRWYRAPELLLNSSEYTGAIDIWSVGCIFMEILRRETLFPGKDYVQQLKL 245 Query 1103 ------SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156 SP L+ + + V +L + ++ R P+ P + L + + Sbjct 246 ITELLGSPDDSDLDFLRSDNARKYVKQLPHVQKQSFREKFPNISPMAL-DLAEKMLVFDP 304 Query 1157 SFRPTFENLI--PILKTVHEKYQGQA-PSVFS 1185 S R T + + P L ++HE + P+ FS Sbjct 305 SKRITVDEALKQPYLASLHEINEEPTCPTPFS 336 Score = 129 bits (323), Expect = 8e-31, Method: Composition-based stats. Identities = 39/236 (17%), Positives = 81/236 (34%), Gaps = 44/236 (19%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 + K I + +G+G V + V +K Sbjct 27 ELSSKYIPPIEPIGRGAYGIVC------------------------CATNSETNEEVAIK 62 Query 643 VLDPSHHDIALAF--YETASLMSQVSHTHLAFVHGVCVRGPE-----NIMVTEYVEHGPL 695 + + + A L+S + H ++ + + + +V E ++ L Sbjct 63 KIANAFDNRVDAKRTLREIKLLSHMDHDNVIKIKDIIELPEKERFEDVYIVYELMD-TDL 121 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + Q+ L Y+ + N++H ++ N++L T+ + Sbjct 122 HQIIRSTQ-TLTDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLVLN-------TNCDL 173 Query 756 KLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 K+ D G+ + E E V + APE L ++ + A+D W G +EI Sbjct 174 KICDFGLARTSNETEIMTEYVVTRWYRAPELLLN-SSEYTGAIDIWSVGCIFMEIL 228 >sp|Q9LS95|PERK6_ARATH Putative proline-rich receptor-like protein kinase PERK6 OS=Arabidopsis thaliana OX=3702 GN=PERK6 PE=2 SV=2 Length=700 Score = 223 bits (568), Expect = 5e-60, Method: Composition-based stats. Identities = 76/278 (27%), Positives = 115/278 (41%), Gaps = 20/278 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G FG V G+ +AVK+LKA G R ++ E+DI+ ++H ++ Sbjct 343 LGQGGFGYVHKGIL-----PNGKEIAVKSLKAGSGQGERE-FQAEVDIISRVHHRFLVSL 396 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLH---A 1016 G C G++ LV E++P +L +L S + L A +G+AYLH Sbjct 397 VGYCIAGGQR--MLVYEFLPNDTLEFHLHGKSGKVLDWPTRLKIALGSAKGLAYLHEDCH 454 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 IHRD+ A N+LLD K+ DFGLAK + + R + APE Sbjct 455 PRIIHRDIKASNILLDESFEAKVADFGLAKLSQDNVTHVSTR--IMGTFGYLAPEYASSG 512 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL----RLTELLERGE 1132 K SDV+SFGV L EL+T L+ A+ +EL++ Sbjct 513 KLTDRSDVFSFGVMLLELVTGRRPVDLTGEMEDSLVDWARPICLNAAQDGDYSELVDPRL 572 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 ++ A RP ++ L+ Sbjct 573 ENQYEPHEMAQMVACAAAAVRHSARRRPKMSQIVRALE 610 Score = 217 bits (553), Expect = 4e-58, Method: Composition-based stats. Identities = 55/269 (20%), Positives = 96/269 (36%), Gaps = 46/269 (17%) Query 574 LNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 N S ++ + + +Q LGQG V++G L Sbjct 320 FNKSTFTYDELAAATQGFSQSRLLGQGGFGYVHKGILPNGK------------------- 360 Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 + +K L F ++S+V H L + G C+ G + ++V E++ Sbjct 361 ------EIAVKSLKAGSGQGEREFQAEVDIISRVHHRFLVSLVGYCIAGGQRMLVYEFLP 414 Query 692 HGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGL 747 + L+ L + G + ++ +A A L+YL ++H ++ NILL Sbjct 415 NDTLEFHLHGKSGKVLDWPTRLKIALGSAKGLAYLHEDCHPRIIHRDIKASNILLDE--- 471 Query 748 AEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGA 802 S K++D G+ + V +LAPE G L+ D + FG Sbjct 472 ----SFEAKVADFGLAKLSQDNVTHVSTRIMGTFGYLAPEYASSG--KLTDRSDVFSFGV 525 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQH 831 LLE+ G P+ E + Sbjct 526 MLLELV-TGRRPVDLTGEMEDSLVDWARP 553 >sp|Q9LRT1|Y3804_ARATH Probably inactive leucine-rich repeat receptor-like protein kinase At3g28040 OS=Arabidopsis thaliana OX=3702 GN=At3g28040 PE=1 SV=1 Length=1016 Score = 228 bits (580), Expect = 5e-60, Method: Composition-based stats. Identities = 68/281 (24%), Positives = 109/281 (39%), Gaps = 15/281 (5%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG FG V Y G +AVK L Q+ + +E+ IL H +++ Sbjct 731 RIGEGVFGTV----YKAPLGEQGRNLAVKKLVPSPILQNLEDFDREVRILAKAKHPNLVS 786 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-----SIGLAQLLLFAQQICEGMAYLHA 1016 KG LV EY+P G+L+ L + +G+AYLH Sbjct 787 IKGYFWTPDLH--LLVSEYIPNGNLQSKLHEREPSTPPLSWDVRYKIILGTAKGLAYLHH 844 Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC- 1072 IH +L N+LLD KI DFGL++ + + + + APE Sbjct 845 TFRPTTIHFNLKPTNILLDEKNNPKISDFGLSRLLTTQDGNTMNNNRFQNALGYVAPELE 904 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + DV+ FGV + EL+T + F+ L + + + E ++ Sbjct 905 CQNLRVNEKCDVYGFGVLILELVTGRRPVEYGEDSFVILSDHVRVMLEQGNVLECIDPVM 964 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + V L C S RPT ++ IL+ ++ Sbjct 965 EEQYSEDEVLPVLKLALVCTSQIPSNRPTMAEIVQILQVIN 1005 Score = 176 bits (447), Expect = 1e-43, Method: Composition-based stats. Identities = 62/332 (19%), Positives = 114/332 (34%), Gaps = 62/332 (19%) Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 F R + + + S +G+G VY+ L +G Sbjct 717 EFERNPESLLNKASRIGEGVFGTVYKAPLGEQGRNL------------------------ 752 Query 640 VLKVLDPSH-HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +K L PS F ++++ H +L + G +++V+EY+ +G L Sbjct 753 AVKKLVPSPILQNLEDFDREVRILAKAKHPNLVSIKGYFWTPDLHLLVSEYIPNGNLQSK 812 Query 699 LR-RERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAEGTS 752 L RE P++W + + A L+YL + +H N+ NILL Sbjct 813 LHEREPSTPPLSWDVRYKIILGTAKGLAYLHHTFRPTTIHFNLKPTNILLDEKNNP---- 868 Query 753 PFIKLSDPGVGLGALSREERVER-------IPWLAPECLPGGANSLSTAMDKWGFGATLL 805 K+SD G+ +++ + ++APE L ++ D +GFG +L Sbjct 869 ---KISDFGLSRLLTTQDGNTMNNNRFQNALGYVAPE-LECQNLRVNEKCDVYGFGVLIL 924 Query 806 EICFDGEAPLQSRSP----SEKEHFYQRQHRLPEPSCPQLAT------------LTSQCL 849 E+ S+ Q + E P + L C Sbjct 925 ELVTGRRPVEYGEDSFVILSDHVRVMLEQGNVLECIDPVMEEQYSEDEVLPVLKLALVCT 984 Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 + P+ RP+ I++ L + ++ Sbjct 985 SQIPSNRPTMAEIVQILQVINSPVPHRIMDSF 1016 >sp|Q9SR87|LRK61_ARATH Probable L-type lectin-domain containing receptor kinase VI.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK61 PE=2 SV=1 Length=693 Score = 223 bits (567), Expect = 5e-60, Method: Composition-based stats. Identities = 69/299 (23%), Positives = 121/299 (40%), Gaps = 22/299 (7%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH 940 P + K+ +G G FG V N + +AVK + ++ Q Sbjct 352 YPHRFRYRDLYLATKKFKESEIIGTGGFGIVYRG-----NLSSSGPIAVKKITSN-SLQG 405 Query 941 RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------ 994 + EI+ L L H++++ +G C+ + E L L+ +Y+P GSL L + Sbjct 406 VREFMAEIESLGRLGHKNLVNLQGWCKHKNE--LLLIYDYIPNGSLDSLLYQTPRRNGIV 463 Query 995 IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEG 1051 + + I G+ YLH + +HRD+ NVL+D D K+GDFGLA+ G Sbjct 464 LPWDVRFEIIKGIASGLLYLHEEWEQIVVHRDVKPSNVLIDEDMNAKLGDFGLARLYERG 523 Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLEL 1111 + + + APE + K ASDV++FGV L E++ + + + L Sbjct 524 TLTQTTK--IVGTLGYMAPELTRNGKGSTASDVFAFGVLLLEIVCGNKPTNA---ENFFL 578 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 T + ++++ + + C + FRP+ ++ L Sbjct 579 ADWVMEFHTNGGILCVVDQNLGSSFNGREAKLALVVGLLCCHQKPKFRPSMRMVLRYLN 637 Score = 210 bits (535), Expect = 8e-56, Method: Composition-based stats. Identities = 64/314 (20%), Positives = 108/314 (34%), Gaps = 73/314 (23%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + K+ + +G G VY G L G + +K Sbjct 363 LATKKFKESEIIGTGGFGIVYRGNLSSSGP-------------------------IAVKK 397 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---- 699 + + F + ++ H +L + G C E +++ +Y+ +G LD L Sbjct 398 ITSNSLQGVREFMAEIESLGRLGHKNLVNLQGWCKHKNELLLIYDYIPNGSLDSLLYQTP 457 Query 700 RRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIK 756 RR +P + + + +AS L YL + +VH +V N+L+ K Sbjct 458 RRNGIVLPWDVRFEIIKGIASGLLYLHEEWEQIVVHRDVKPSNVLIDE-------DMNAK 510 Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 L D G+ + V + ++APE G STA D + FG LLEI Sbjct 511 LGDFGLARLYERGTLTQTTKIVGTLGYMAPELTRNGKG--STASDVFAFGVLLLEIV--- 565 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ--------------------CLTY 851 P+ E+F+ + + + + Q C Sbjct 566 ----CGNKPTNAENFFLADWVMEFHTNGGILCVVDQNLGSSFNGREAKLALVVGLLCCHQ 621 Query 852 EPTQRPSFRTILRD 865 +P RPS R +LR Sbjct 622 KPKFRPSMRMVLRY 635 >sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo sapiens OX=9606 GN=NUAK1 PE=1 SV=1 Length=661 Score = 222 bits (565), Expect = 5e-60, Method: Composition-based stats. Identities = 68/292 (23%), Positives = 114/292 (39%), Gaps = 31/292 (11%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC- 936 K + LG+G +GKV T +G +VA+K+++ D Sbjct 36 PRKPHGVKRHHHKHNLKHRYELQETLGKGTYGKVK----RATERFSGRVVAIKSIRKDKI 91 Query 937 -GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHS 994 Q ++EI+I+ +L H HII E++ + + ++MEY G L DY+ R Sbjct 92 KDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDK--IVIIMEYASKGELYDYISERRR 149 Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + + F +QI + Y H +HRDL N+LLD++ +KI DFGL+ + Sbjct 150 LSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKD--- 206 Query 1055 YRVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 + + + +PE + + D W+ GV LY L+ Sbjct 207 -KFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFD----------- 254 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L + GE R P + L++ R T E++ Sbjct 255 ----GFDHKNLIRQISSGEY--REPTQPSDARGLIRWMLMVNPDRRATIEDI 300 Score = 169 bits (428), Expect = 2e-42, Method: Composition-based stats. Identities = 57/357 (16%), Positives = 101/357 (28%), Gaps = 41/357 (11%) Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGS 613 PG + A PR + + H+ + K LG+GT V R G Sbjct 20 PGSPREAVAGATAALEPRKPHGVKRHHHKHNLKHRYELQETLGKGTYGKVKRATERFSGR 79 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETASLMSQVSHTHL 670 V +K + + +MS ++H H+ Sbjct 80 ------------------------VVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHI 115 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730 ++ V + +++ EY G L ++ ER + +Q+ SA+ Y + Sbjct 116 ISIYEVFENKDKIVIIMEYASKGELYDYI-SERRRLSERETRHFFRQIVSAVHYCHKNGV 174 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGG 787 VH ++ NILL + IK++D G+ + + +PE + G Sbjct 175 VHRDLKLENILLD-------DNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGR 227 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ 847 +D W G L + G P L Sbjct 228 PYR-GPEVDSWALGVLLYTLV-YGTMPFDGFDHKNLIRQISSGEYREPTQPSDARGLIRW 285 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 L P +R + I + + S + + L Sbjct 286 MLMVNPDRRATIEDIANHWWVNWGYKSSVCDCDALHDSESPLLARIIDWHHRSTGLQ 342 >sp|Q2WGK3|HOG1_TRIHA Mitogen-activated protein kinase hog1 OS=Trichoderma harzianum OX=5544 GN=hog1 PE=1 SV=1 Length=356 Score = 213 bits (542), Expect = 6e-60, Method: Composition-based stats. Identities = 68/293 (23%), Positives = 112/293 (38%), Gaps = 31/293 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VAVK + K P +E+ +L+ L HE++ Sbjct 24 QPVGMGAFGLVC----SARDQLTNQNVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENV 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHE 1174 L + ER P + L++ + R T + L+ H+ Sbjct 252 SLPKRERQPLRNKFKNADDSAIDLLERMLVFDPKKRVTATQALAHEYLQPYHD 304 Score = 130 bits (326), Expect = 3e-31, Method: Composition-based stats. Identities = 37/231 (16%), Positives = 75/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E D + M + RD+ V +K ++ P +A Y Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAVKKIMKPFSTPVLAKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q2ULU3|STE20_ASPOR Serine/threonine-protein kinase ste20 OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=ste20 PE=3 SV=1 Length=848 Score = 225 bits (574), Expect = 6e-60, Method: Composition-based stats. Identities = 60/275 (22%), Positives = 119/275 (43%), Gaps = 23/275 (8%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 + + +G+G G V + ++GTG VA+K + D P+ + EI +++ Sbjct 563 PTKMYYNLNKIGQGASGGV----FTAYHNGTGSCVAIKQMNLDLQPK-KDLIINEIIVMK 617 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 H++I+ + + L +VMEY+ GSL D + + + Q+ ++ G+ Sbjct 618 DSKHKNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMSEGQIAAVCRETLNGLQ 675 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 +LH++ IHRD+ + N+LL D +K+ DFG + ++ + R +W APE Sbjct 676 HLHSKGVIHRDIKSDNILLSLDGNIKLTDFGFCAQI---NDSHNKRNTMVGTPYWMAPEV 732 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + ++ D+WS G+ E++ + + L IA ++ + L Sbjct 733 VTRKEYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLIATNGTPTIKDEQSLTPVF 791 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 R + HL + + R + +L+ Sbjct 792 R---------DFLHLA---LKVDPEKRASAHDLLK 814 Score = 176 bits (446), Expect = 7e-44, Method: Composition-based stats. Identities = 53/293 (18%), Positives = 93/293 (32%), Gaps = 44/293 (15%) Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651 L+ +GQG V+ G V +K ++ Sbjct 570 LNKIGQGASGGVF------------------------TAYHNGTGSCVAIKQMNLDLQPK 605 Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711 +M H ++ + G + +V EY+E G L + + Sbjct 606 KDLIINEIIVMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVV--TFNIMSEGQI 663 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--- 768 V ++ + L +L +K ++H ++ NILL+ IKL+D G Sbjct 664 AAVCRETLNGLQHLHSKGVIHRDIKSDNILLS-------LDGNIKLTDFGFCAQINDSHN 716 Query 769 -REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 R V W+APE + +D W G +E+ +GE P + SP + Sbjct 717 KRNTMVGTPYWMAPEVVT--RKEYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLI 773 Query 828 QRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 + P L +P +R S +L+ L+ Sbjct 774 ATNGTPTIKDEQSLTPVFRDFLHLALKVDPEKRASAHDLLKHPFMSFCAPLSH 826 >sp|P42818|KPK1_ARATH Serine/threonine-protein kinase AtPK1/AtPK6 OS=Arabidopsis thaliana OX=3702 GN=ATPK1 PE=1 SV=1 Length=465 Score = 216 bits (551), Expect = 6e-60, Method: Composition-based stats. Identities = 67/260 (26%), Positives = 110/260 (42%), Gaps = 30/260 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960 +G+G FGKV Y T E+ A+K ++ D H K E DIL + H I+ Sbjct 140 VGKGAFGKV----YQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPFIV 195 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHY 1019 + K Q + L LV++++ G L L + ++ +I +++LH + Sbjct 196 QLKYSF--QTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGI 253 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDL N+L+D D V + DFGLAK E + + APE ++ Sbjct 254 MHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSM----CGTTEYMAPEIVRGKGHD 309 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 A+D WS G+ LYE+LT K + ++++ +L P Sbjct 310 KAADWWSVGILLYEMLTGKPPFLGSKGKIQQ---------------KIVKDKIKL--PQF 352 Query 1140 CPCEVYHLMKNCWETEASFR 1159 E + ++K + E R Sbjct 353 LSNEAHAILKGLLQKEPERR 372 Score = 156 bits (395), Expect = 2e-39, Method: Composition-based stats. Identities = 48/324 (15%), Positives = 102/324 (31%), Gaps = 35/324 (11%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V + + +G+G VY+ R + + D + Sbjct 129 VGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDH------------------I 170 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 ++ +H + A +++++ H + + +V +++ G L L + Sbjct 171 MEKNHAEYMKA---ERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQ- 226 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 G V ++ SA+S+L K ++H ++ NIL+ G + L+D G+ Sbjct 227 GLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDTDG-------HVMLTDFGLA 279 Query 764 LGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 ++APE + G A D W G L E+ G+ P Sbjct 280 KEFEENTRSNSMCGTTEYMAPEIVRG--KGHDKAADWWSVGILLYEML-TGKPPFLGSKG 336 Query 821 SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880 ++ + + +LP+ + + L EP +R + + Sbjct 337 KIQQKIVKDKIKLPQFLSNEAHAILKGLLQKEPERRLGSGLSGAEEIKQHKWFKGINWKK 396 Query 881 NPDSPASDPTVFHKRYLKKIRDLG 904 + I + Sbjct 397 LEAREVMPSFKPEVSGRQCIANFD 420 >sp|A9TF79|SRK2A_PHYPA Serine/threonine-protein kinase SRK2A OS=Physcomitrium patens OX=3218 GN=SRK2A PE=1 SV=1 Length=349 Score = 213 bits (541), Expect = 6e-60, Method: Composition-based stats. Identities = 72/281 (26%), Positives = 117/281 (42%), Gaps = 30/281 (11%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 + + ++D+G G+FG L + T E+VAVK + + G + ++EI Sbjct 6 MHDHDRYELVKDIGSGNFGVARLM----RDKKTRELVAVKYI--ERGEKIDENVQREIIN 59 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICE 1009 R+L H +I+++K L +VMEY G L + + + F QQ+ Sbjct 60 HRSLRHPNIVRFKEVMLTPTH--LAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLIS 117 Query 1010 GMAYLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 G++Y H+ HRDL N LLD +KI DFG +K + + + Sbjct 118 GVSYCHSMQICHRDLKLENTLLDGSPAPRLKICDFGYSK----SSLLHSQPKSTVGTPAY 173 Query 1068 YAPECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSP--PTKFLELIGIAQGQMTVLRL 1124 APE L + ++ +DVWS GVTLY +L + P P F + IG Sbjct 174 IAPEVLSKKEYDGKIADVWSCGVTLYVMLVGAYPFEDPEDPRNFRKTIG----------- 222 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 +L +P E HL+ + + R + + Sbjct 223 -RILSVQYSIPDYVHISVECRHLLSRIFVANPAKRINIQEI 262 Score = 157 bits (397), Expect = 1e-40, Method: Composition-based stats. Identities = 57/332 (17%), Positives = 100/332 (30%), Gaps = 47/332 (14%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 D + +G G RD+ V +K + Sbjct 8 DHDRYELVKDIGSGNFG------------------------VARLMRDKKTRELVAVKYI 43 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + I + H ++ V + +V EY G L + G Sbjct 44 ERG-EKIDENVQREIINHRSLRHPNIVRFKEVMLTPTHLAIVMEYAAGGELFERI-CNAG 101 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 QQL S +SY + + H ++ N LL +P +K+ D G Sbjct 102 RFSEDEARFFFQQLISGVSYCHSMQICHRDLKLENTLLD-----GSPAPRLKICDFGYSK 156 Query 765 GAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 +L + V ++APE L D W G TL + G P + P Sbjct 157 SSLLHSQPKSTVGTPAYIAPEVLSKKEYD-GKIADVWSCGVTLYVMLV-GAYPFED--PE 212 Query 822 EKEHFYQRQHRL--PEPSCPQLATLTSQCLT-------YEPTQRPSFRTILRDLTRLQPH 872 + +F + R+ + S P ++ +C P +R + + I L+ Sbjct 213 DPRNFRKTIGRILSVQYSIPDYVHISVECRHLLSRIFVANPAKRINIQEIKNHEWFLKNL 272 Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 V + DP + + +R + Sbjct 273 PADLVDLADRSYDFEDPNHPPQSIEEIMRIIS 304 >sp|P0C5D6|SAPK3_ORYSJ Serine/threonine-protein kinase SAPK3 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK3 PE=1 SV=1 Length=334 Score = 212 bits (540), Expect = 6e-60, Method: Composition-based stats. Identities = 77/283 (27%), Positives = 118/283 (42%), Gaps = 33/283 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +LG G+FG L + + E+VAVK + + G + ++EI R+L H +II+ Sbjct 10 ELGAGNFGVARLV----RDKRSKELVAVKYI--ERGKKIDENVQREIINHRSLRHPNIIR 63 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 +K C L +VMEY G L + + + F QQ+ G++Y H+ Sbjct 64 FKEVCLTPTH--LAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSLEIC 121 Query 1021 HRDLAARNVLLDNDRL--VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N LLD VKI DFG +K + + + +P + APE L ++ Sbjct 122 HRDLKLENTLLDGSPTPRVKICDFGYSK---SALLHSKPKSTVGTPA-YIAPEVLSRKEY 177 Query 1079 YYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 DVWS GVTLY +L + P G R T G + P Sbjct 178 DGKVADVWSCGVTLYVMLVGSYPFEDP------------GDPRNFRKTISRILGVQYSIP 225 Query 1138 DK--CPCEVYHLMKNCWETEASFRPTFENLIP---ILKTVHEK 1175 D + L+ + + S R T + LK + ++ Sbjct 226 DYVRVSSDCRRLLSQIFVADPSKRITIPEIKKHTWFLKNLPKE 268 Score = 159 bits (401), Expect = 2e-41, Method: Composition-based stats. Identities = 55/295 (19%), Positives = 89/295 (30%), Gaps = 41/295 (14%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ L LG G RD+ + V +K ++ Sbjct 2 EERYEALKELGAGNFG------------------------VARLVRDKRSKELVAVKYIE 37 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 I + H ++ VC+ +V EY G L + G Sbjct 38 RGKK-IDENVQREIINHRSLRHPNIIRFKEVCLTPTHLAIVMEYAAGGELFEQI-CTAGR 95 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 QQL S +SY + + H ++ N LL +P +K+ D G Sbjct 96 FSEDEARYFFQQLISGVSYCHSLEICHRDLKLENTLLD-----GSPTPRVKICDFGYSKS 150 Query 766 AL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 AL + V ++APE L D W G TL + P Sbjct 151 ALLHSKPKSTVGTPAYIAPEVLSRKEYD-GKVADVWSCGVTLYVMLVGSYPFEDPGDPRN 209 Query 823 KEHFYQR----QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 R Q+ +P+ L SQ +P++R + I + L+ Sbjct 210 FRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFVADPSKRITIPEIKKHTWFLKN 264 >sp|A2ZAB5|SAPK3_ORYSI Serine/threonine-protein kinase SAPK3 OS=Oryza sativa subsp. indica OX=39946 GN=SAPK3 PE=1 SV=2 Length=334 Score = 212 bits (540), Expect = 6e-60, Method: Composition-based stats. Identities = 77/283 (27%), Positives = 118/283 (42%), Gaps = 33/283 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +LG G+FG L + + E+VAVK + + G + ++EI R+L H +II+ Sbjct 10 ELGAGNFGVARLV----RDKRSKELVAVKYI--ERGKKIDENVQREIINHRSLRHPNIIR 63 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 +K C L +VMEY G L + + + F QQ+ G++Y H+ Sbjct 64 FKEVCLTPTH--LAIVMEYAAGGELFEQICTAGRFSEDEARYFFQQLISGVSYCHSLEIC 121 Query 1021 HRDLAARNVLLDNDRL--VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N LLD VKI DFG +K + + + +P + APE L ++ Sbjct 122 HRDLKLENTLLDGSPTPRVKICDFGYSK---SALLHSKPKSTVGTPA-YIAPEVLSRKEY 177 Query 1079 YYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 DVWS GVTLY +L + P G R T G + P Sbjct 178 DGKVADVWSCGVTLYVMLVGSYPFEDP------------GDPRNFRKTISRILGVQYSIP 225 Query 1138 DK--CPCEVYHLMKNCWETEASFRPTFENLIP---ILKTVHEK 1175 D + L+ + + S R T + LK + ++ Sbjct 226 DYVRVSSDCRRLLSQIFVADPSKRITIPEIKKHTWFLKNLPKE 268 Score = 159 bits (401), Expect = 2e-41, Method: Composition-based stats. Identities = 55/295 (19%), Positives = 89/295 (30%), Gaps = 41/295 (14%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ L LG G RD+ + V +K ++ Sbjct 2 EERYEALKELGAGNFG------------------------VARLVRDKRSKELVAVKYIE 37 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 I + H ++ VC+ +V EY G L + G Sbjct 38 RGKK-IDENVQREIINHRSLRHPNIIRFKEVCLTPTHLAIVMEYAAGGELFEQI-CTAGR 95 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 QQL S +SY + + H ++ N LL +P +K+ D G Sbjct 96 FSEDEARYFFQQLISGVSYCHSLEICHRDLKLENTLLD-----GSPTPRVKICDFGYSKS 150 Query 766 AL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 AL + V ++APE L D W G TL + P Sbjct 151 ALLHSKPKSTVGTPAYIAPEVLSRKEYD-GKVADVWSCGVTLYVMLVGSYPFEDPGDPRN 209 Query 823 KEHFYQR----QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 R Q+ +P+ L SQ +P++R + I + L+ Sbjct 210 FRKTISRILGVQYSIPDYVRVSSDCRRLLSQIFVADPSKRITIPEIKKHTWFLKN 264 >sp|Q6H7D2|SIT1_ORYSJ L-type lectin-domain containing receptor kinase SIT1 OS=Oryza sativa subsp. japonica OX=39947 GN=SIT1 PE=1 SV=1 Length=674 Score = 222 bits (566), Expect = 6e-60, Method: Composition-based stats. Identities = 71/275 (26%), Positives = 116/275 (42%), Gaps = 16/275 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG+V Y + +AVK + + Q + E+ + L H ++++ Sbjct 363 LGFGGFGRV----YKGVLLVSRVEIAVKKVSHE-SRQGMKEFIAEVVSIGQLRHRNLVQL 417 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQH- 1018 G C +GE L LV +Y+P GSL YL + AQ + I + YLH Sbjct 418 LGYCRQKGE--LLLVYDYMPNGSLDKYLYAENSKILSWAQRFRIIKGIASSILYLHEDWE 475 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRD+ A NVLLD + ++GDFGLA+ G + + + + APE Sbjct 476 QVVLHRDIKASNVLLDAEMNCRLGDFGLARLYDRGTDPHTTH--VVGTIGYLAPELGHTG 533 Query 1077 KFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + ASD+++FGV + E+ Q L L+ + +T+ ++ + Sbjct 534 RPSKASDIFAFGVFMLEVTCGRRPVLQDTNGGQLLLVDMVLEHWRQGTVTDAVDPRLQGD 593 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + V L C S RP ++ +L Sbjct 594 FAVEEASLVLKLCLLCSHPLPSARPGIRQVVQLLD 628 Score = 212 bits (539), Expect = 2e-56, Method: Composition-based stats. Identities = 64/339 (19%), Positives = 114/339 (34%), Gaps = 61/339 (18%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + LG G VY+G L V + + +K + Sbjct 353 ATNGFSDERLLGFGGFGRVYKGVLLV------------------------SRVEIAVKKV 388 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 F + Q+ H +L + G C + E ++V +Y+ +G LD +L E Sbjct 389 SHESRQGMKEFIAEVVSIGQLRHRNLVQLLGYCRQKGELLLVYDYMPNGSLDKYLYAENS 448 Query 705 H-VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + A + + + +AS++ YL + ++H ++ N+LL +L D Sbjct 449 KILSWAQRFRIIKGIASSILYLHEDWEQVVLHRDIKASNVLLD-------AEMNCRLGDF 501 Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ V I +LAPE G S A D + FG +LE+ G P+ Sbjct 502 GLARLYDRGTDPHTTHVVGTIGYLAPEL--GHTGRPSKASDIFAFGVFMLEV-TCGRRPV 558 Query 816 QSRSPSEKEHF------YQRQHRLPEPSCPQL------------ATLTSQCLTYEPTQRP 857 + + + RQ + + P+L L C P+ RP Sbjct 559 LQDTNGGQLLLVDMVLEHWRQGTVTDAVDPRLQGDFAVEEASLVLKLCLLCSHPLPSARP 618 Query 858 SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896 R +++ L P ++ + A Sbjct 619 GIRQVVQLLDGAMPLPELSQAHLSCNMLALMQNQMGNSC 657 >sp|Q75DK7|STE20_EREGS Serine/threonine-protein kinase STE20 OS=Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=STE20 PE=3 SV=2 Length=970 Score = 227 bits (578), Expect = 6e-60, Method: Composition-based stats. Identities = 65/282 (23%), Positives = 118/282 (42%), Gaps = 25/282 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G G V Y GT VA+K + + P+ + EI +++ H +I+ Sbjct 688 KIGQGASGGV----YTAYEIGTNASVAIKQMNLEKQPK-KELIINEILVMKGSRHNNIVN 742 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 + +G+ L ++MEY+ GSL D + + Q+ +++ G+ +LH++ IH Sbjct 743 FIDSYLLKGD--LWVIMEYMEGGSLTDVVTHCILTEGQIAAVSRETLRGLHFLHSKGVIH 800 Query 1022 RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYA 1081 RD+ + N+LL D +K+ DFG + +E R +W APE + ++ Sbjct 801 RDIKSDNILLSMDGNIKLTDFGFCAQI---NETNLKRTTMVGTPYWMAPEVVSRKEYGPK 857 Query 1082 SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCP 1141 D+WS G+ + E++ + T L IA L+ + L Sbjct 858 VDIWSLGIMIIEMI-EGEPPYLNETPLRALYLIATNGTPKLKDADSL------------S 904 Query 1142 CEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAP 1181 + + C + + R T L+ + V E AP Sbjct 905 PVLKRFLSWCLQVSPNDRATAMELLYDKFIVEVAEANASLAP 946 Score = 185 bits (469), Expect = 2e-46, Method: Composition-based stats. Identities = 51/277 (18%), Positives = 90/277 (32%), Gaps = 44/277 (16%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 +GQG VY + G V +K ++ Sbjct 688 KIGQGASGGVY------------------------TAYEIGTNASVAIKQMNLEKQPKKE 723 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 +M H ++ + + ++ EY+E G L + + Sbjct 724 LIINEILVMKGSRHNNIVNFIDSYLLKGDLWVIMEYMEGGSLTDVVTH--CILTEGQIAA 781 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA----LSR 769 V+++ L +L +K ++H ++ NILL+ IKL+D G L R Sbjct 782 VSRETLRGLHFLHSKGVIHRDIKSDNILLS-------MDGNIKLTDFGFCAQINETNLKR 834 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 V W+APE + +D W G ++E+ +GE P + +P + Sbjct 835 TTMVGTPYWMAPEVVS--RKEYGPKVDIWSLGIMIIEMI-EGEPPYLNETPLRALYLIAT 891 Query 830 QHRLP----EPSCPQLATLTSQCLTYEPTQRPSFRTI 862 + P L S CL P R + + Sbjct 892 NGTPKLKDADSLSPVLKRFLSWCLQVSPNDRATAMEL 928 >sp|Q52PH6|HOG1_ALTBR Mitogen-activated protein kinase HOG1 OS=Alternaria brassicicola OX=29001 GN=HOG1 PE=3 SV=1 Length=355 Score = 213 bits (542), Expect = 6e-60, Method: Composition-based stats. Identities = 66/276 (24%), Positives = 107/276 (39%), Gaps = 29/276 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VA+K + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SAKDQLTSQAVAIKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVQ 251 Query 1127 LLERGERLPRP---DKCPCEVYHLMKNCWETEASFR 1159 L + ER P + L++N + R Sbjct 252 SLPKRERQPLSNKFKNAEPQAVDLLENMLVFDPKKR 287 Score = 134 bits (337), Expect = 1e-32, Method: Composition-based stats. Identities = 35/231 (15%), Positives = 74/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + +D+ V +K ++ P ++ Y Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSAKDQLTSQAVAIKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q9LPZ9|SD113_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase SD1-13 OS=Arabidopsis thaliana OX=3702 GN=SD113 PE=1 SV=2 Length=830 Score = 225 bits (573), Expect = 6e-60, Method: Composition-based stats. Identities = 74/279 (27%), Positives = 110/279 (39%), Gaps = 17/279 (6%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG+G FG V G +AVK L G + + I L H +++ Sbjct 516 NKLGQGGFGAVYKGRLQE-----GLDIAVKRLSRTSGQGVEEFVNEVVVI-SKLQHRNLV 569 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016 + G C + E+ LV E++P L YL + + IC G+ YLH Sbjct 570 RLLGFCIEGEER--MLVYEFMPENCLDAYLFDPVKQRLLDWKTRFNIIDGICRGLMYLHR 627 Query 1017 Q---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRDL A N+LLD + KI DFGLA+ +G+E + APE Sbjct 628 DSRLKIIHRDLKASNILLDENLNPKISDFGLARIF-QGNEDEVSTVRVVGTYGYMAPEYA 686 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCD-SSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 F SDV+S GV L E+++ SS + L A L++ Sbjct 687 MGGLFSEKSDVFSLGVILLEIVSGRRNSSFYNDGQNPNLSAYAWKLWNTGEDIALVDPVI 746 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 + H+ C + A+ RP+ +I +L + Sbjct 747 FEECFENEIRRCVHVGLLCVQDHANDRPSVATVIWMLSS 785 Score = 216 bits (551), Expect = 4e-57, Method: Composition-based stats. Identities = 57/274 (21%), Positives = 97/274 (35%), Gaps = 46/274 (17%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 + L L + V + + LGQG VY+GRL+ Sbjct 495 KELPLFEFQVLAVATNNFSITNKLGQGGFGAVYKGRLQEG-------------------- 534 Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 L + +K L + F ++S++ H +L + G C+ G E ++V E++ Sbjct 535 -----LDIAVKRLSRTSGQGVEEFVNEVVVISKLQHRNLVRLLGFCIEGEERMLVYEFMP 589 Query 692 HGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLG 746 LD +L + W + + + L YL ++H ++ NILL Sbjct 590 ENCLDAYLFDPVKQRLLDWKTRFNIIDGICRGLMYLHRDSRLKIIHRDLKASNILLDE-- 647 Query 747 LAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800 + K+SD G+ +S V ++APE GG S D + Sbjct 648 -----NLNPKISDFGLARIFQGNEDEVSTVRVVGTYGYMAPEYAMGGL--FSEKSDVFSL 700 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834 G LLEI G + + + +L Sbjct 701 GVILLEIVS-GRRNSSFYNDGQNPNLSAYAWKLW 733 >sp|Q9S9M1|WAKLE_ARATH Wall-associated receptor kinase-like 5 OS=Arabidopsis thaliana OX=3702 GN=WAKL5 PE=2 SV=2 Length=731 Score = 223 bits (569), Expect = 6e-60, Method: Composition-based stats. Identities = 69/279 (25%), Positives = 111/279 (40%), Gaps = 18/279 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G G V G+++AVK K + EI +L + H +I+K Sbjct 438 LGKGSQGTVYKGM-----MVDGKIIAVKRSKV-VDEDKLEKFINEIILLSQINHRNIVKL 491 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHAQ- 1017 GCC + E + LV EY+P G + L S + L A +I + Y+H+ Sbjct 492 IGCCLE-TEVPI-LVYEYIPNGDMFKRLHDESDDYAMTWEVRLRIAIEIAGALTYMHSAA 549 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 HRD+ N+LLD K+ DFG +++V + G + PE Sbjct 550 SFPIYHRDIKTTNILLDEKYGAKVSDFGTSRSVTIDQTHLTTMVAG--TFGYMDPEYFLS 607 Query 1076 YKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 ++ SDV+SFGV L EL+T S+ + L M R+ ++++ + Sbjct 608 SQYTDKSDVYSFGVVLVELITGEKPLSRIRSEEGRGLATHFLEAMKENRVIDIIDIRIKE 667 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 V L + C + RP L+ + Sbjct 668 ESKLDQLMAVAKLARKCLSRKGIKRPNMREASLELERIR 706 Score = 211 bits (537), Expect = 8e-56, Method: Composition-based stats. Identities = 58/305 (19%), Positives = 105/305 (34%), Gaps = 63/305 (21%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + LG+G++ VY+G + + +K Sbjct 428 ATDNFSVKRVLGKGSQGTVYKGMMVDGKI-------------------------IAVKRS 462 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D F L+SQ++H ++ + G C+ I+V EY+ +G + L E Sbjct 463 KVVDEDKLEKFINEIILLSQINHRNIVKLIGCCLETEVPILVYEYIPNGDMFKRLHDESD 522 Query 705 HVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 M W ++ +A ++A AL+Y+ + + H ++ NILL A K+SD Sbjct 523 DYAMTWEVRLRIAIEIAGALTYMHSAASFPIYHRDIKTTNILLDEKYGA-------KVSD 575 Query 760 PGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G + ++ PE ++ + D + FG L+E+ GE P Sbjct 576 FGTSRSVTIDQTHLTTMVAGTFGYMDPEYFL--SSQYTDKSDVYSFGVVLVELI-TGEKP 632 Query 815 LQSRSPSEKEHFYQRQHRLPE------------------PSCPQLATLTSQCLTYEPTQR 856 L E + +A L +CL+ + +R Sbjct 633 LSRIRSEEGRGLATHFLEAMKENRVIDIIDIRIKEESKLDQLMAVAKLARKCLSRKGIKR 692 Query 857 PSFRT 861 P+ R Sbjct 693 PNMRE 697 >sp|Q0U4L8|HOG1_PHANO Mitogen-activated protein kinase HOG1 OS=Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) OX=321614 GN=HOG1 PE=3 SV=2 Length=355 Score = 213 bits (542), Expect = 6e-60, Method: Composition-based stats. Identities = 67/276 (24%), Positives = 107/276 (39%), Gaps = 29/276 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VA+K + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SAKDQLTSQAVAIKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 DVWS G E+L + + EL+G + LR + Sbjct 192 DVEVDVWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIHTICSENTLRFVQ 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFR 1159 L + ER P + L++N + R Sbjct 252 SLPKRERQPLANKFKNAEPAAVDLLENMLVFDPKKR 287 Score = 135 bits (339), Expect = 5e-33, Method: Composition-based stats. Identities = 34/213 (16%), Positives = 69/213 (32%), Gaps = 18/213 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + +D+ V +K ++ P ++ Y Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSAKDQLTSQAVAIKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + APE + +D W G E+ Sbjct 177 RYYRAPE-IMLTWQKYDVEVDVWSAGCIFAEML 208 >sp|P34925|RYK_HUMAN Tyrosine-protein kinase RYK OS=Homo sapiens OX=9606 GN=RYK PE=1 SV=3 Length=607 Score = 220 bits (561), Expect = 7e-60, Method: Composition-based stats. Identities = 85/281 (30%), Positives = 136/281 (48%), Gaps = 26/281 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVA-VKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 L EG FG++ D E A VK +K + E LR L+H +++ Sbjct 336 LQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLP 395 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR---------HSIGLAQLLLFAQQICEGMA 1012 C ++GEK + +++ Y+ G+L+ +L + +I L+ A QI GM+ Sbjct 396 ITHVCIEEGEKPM-VILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMS 454 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 YL + IH+DLAARN ++D+ VKI D L++ + +Y+ + ++ + PV W A E Sbjct 455 YLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFP-MDYHCLGDNENRPVRWMALES 513 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 L +F ASDVW+FGVTL+EL+T L + + L+ G Sbjct 514 LVNNEFSSASDVWAFGVTLWELMT--------------LGQTPYVDIDPFEMAAYLKDGY 559 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 R+ +P CP E++ +M CW + RP F+ L+ L H Sbjct 560 RIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFH 600 Score = 189 bits (480), Expect = 2e-49, Method: Composition-based stats. Identities = 65/345 (19%), Positives = 136/345 (39%), Gaps = 49/345 (14%) Query 547 LRRCCLPQPGETSNLIIMRGARASPRTLNL----SQLSFHRVDQKEITQLSHLGQGTRTN 602 LR ++ +R + R++ L ++ + ++ IT L +GT Sbjct 284 LRADTPNNATPITSYPTLRIEKNDLRSVTLLEAKGKVKDIAISRERITLKDVLQEGTFGR 343 Query 603 VYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF-YETASL 661 ++ G L + +D +E + +K + +I + + Sbjct 344 IFHGIL-------------------IDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCK 384 Query 662 MSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDVWLR-------RERGHVPMAWKMV 713 + + H +L + VC+ G + +++ Y+ G L ++LR + + Sbjct 385 LRGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVH 444 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV 773 +A Q+A +SYL + ++H ++ RN ++ + +K++D + + Sbjct 445 MAIQIACGMSYLARREVIHKDLAARNCVID-------DTLQVKITDNALSRDLFPMDYHC 497 Query 774 ------ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 + W+A E L N S+A D W FG TL E+ G+ P P E + Sbjct 498 LGDNENRPVRWMALESLVN--NEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYL 555 Query 828 QRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + +R+ P +L + + C +P +RP F+ +++ LT Sbjct 556 KDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFH 600 >sp|Q32L23|LIMK2_BOVIN LIM domain kinase 2 OS=Bos taurus OX=9913 GN=LIMK2 PE=2 SV=1 Length=638 Score = 221 bits (563), Expect = 7e-60, Method: Composition-based stats. Identities = 77/302 (25%), Positives = 130/302 (43%), Gaps = 38/302 (13%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI 948 +F L LG+G FG+ T+ TG+++ + L C + + + E+ Sbjct 323 QQIFRPCDLIHGEVLGKGFFGQ----AIKVTHKATGKVMVMNEL-IRCDEETQKTFLTEV 377 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQI 1007 ++R+L H +++K+ G +K L L+ EY+ G+L+D+L Q + FA+ I Sbjct 378 KVMRSLDHPNVLKFIGVLYK--DKKLNLLTEYIEGGTLKDFLRNVDPFPWQQKVRFAKGI 435 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY------------- 1054 GMAYLH+ IHRDL + N L+ D+ V + DFGL++ + E + Sbjct 436 ASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVEERKKPPVEKATTKKRTL 495 Query 1055 ----YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 + R +W APE L + DV+SFG+ L E++ + + L+ Sbjct 496 RKSDRKKRYTVVGNPYWMAPEMLNGKSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLD 555 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 G L + + P++CP + L C E RP F L + Sbjct 556 F-----GLNVKLFWEKFV--------PEECPPAFFPLAAICCRLEPESRPAFSKLEDFFE 602 Query 1171 TV 1172 + Sbjct 603 AL 604 Score = 200 bits (509), Expect = 8e-53, Method: Composition-based stats. Identities = 62/345 (18%), Positives = 114/345 (33%), Gaps = 62/345 (18%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK-EITQLSHLGQGTRTNVYEGRLRVE 611 P P +++ + +L S ++ + ++ LG+G + + Sbjct 294 PGPSSPKEPLLLSRDISRSESLRCSSSCSQQIFRPCDLIHGEVLGKGFFGQAIKVTHKAT 353 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 G +V+ L + F +M + H ++ Sbjct 354 GK------------------------VMVMNELIRCDEETQKTFLTEVKVMRSLDHPNVL 389 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 GV + + ++TEY+E G L +LR P K+ A+ +AS ++YL + ++ Sbjct 390 KFIGVLYKDKKLNLLTEYIEGGTLKDFLRNVD-PFPWQQKVRFAKGIASGMAYLHSMCII 448 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------------------------GAL 767 H ++ N L+ + ++D G+ Sbjct 449 HRDLNSHNCLI-------KLDKTVVVADFGLSRLIVEERKKPPVEKATTKKRTLRKSDRK 501 Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--FDGEAPLQSRSPSEKEH 825 R V W+APE L G S +D + FG L EI + R+ + Sbjct 502 KRYTVVGNPYWMAPEMLNG--KSYDETVDVFSFGIVLCEIIGQVYADPDCLPRTLDFGLN 559 Query 826 FY-QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + +PE P L + C EP RP+F + L Sbjct 560 VKLFWEKFVPEECPPAFFPLAAICCRLEPESRPAFSKLEDFFEAL 604 >sp|Q09170|CDS1_SCHPO Serine/threonine-protein kinase cds1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=cds1 PE=1 SV=2 Length=460 Score = 216 bits (551), Expect = 7e-60, Method: Composition-based stats. Identities = 77/309 (25%), Positives = 122/309 (39%), Gaps = 40/309 (13%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 V + + + + IR LG G F V L +G+ A+K + Sbjct 145 CQVPVKHSRDSQKNMIKSENSHYEIIRTLGSGTFAVVKL----AVEVNSGKWYAIKIINK 200 Query 935 ------DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 + +++EIDIL++L+H +++ E+ E L +VMEYV G L D Sbjct 201 RKILLTSSEKRATEMFQREIDILKSLHHPGVVQCHEIFENDDE--LFIVMEYVEGGDLMD 258 Query 989 YL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 +L SI +Q+ E + +LH Q HRD+ N+L+ ND +KI DFGLAK Sbjct 259 FLIANGSIDEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKV 318 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLK------EYKFYYASDVWSFGVTLYELLTHCDSS 1101 + H E + + APE LK + + D+WS G LY +LT Sbjct 319 I---HGTGTFLETFCGTMGYLAPEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLT----- 370 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP---DKCPCEVYHLMKNCWETEASF 1158 I + + EL+ +G P ++ E L+ E Sbjct 371 ----------ASIPFASSSQAKCIELISKGAYPIEPLLENEISEEGIDLINRMLEINPEK 420 Query 1159 RPTFENLIP 1167 R + + Sbjct 421 RISESEALQ 429 Score = 155 bits (391), Expect = 7e-39, Method: Composition-based stats. Identities = 54/327 (17%), Positives = 95/327 (29%), Gaps = 49/327 (15%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 SQ + + + + LG GT V G + + L R E Sbjct 155 SQKNMIKSENSHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATE 214 Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 + F ++ + H + H + E +V EYVE G L Sbjct 215 M-----------------FQREIDILKSLHHPGVVQCHEIFENDDELFIVMEYVEGGDLM 257 Query 697 VWL-----RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 +L E+ P+ +++ +L + + H ++ NIL+ Sbjct 258 DFLIANGSIDEQDCKPLLKQLLETL------LHLHKQGVTHRDIKPENILITN------- 304 Query 752 SPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGG----ANSLSTAMDKWGFGAT 803 +K+SD G+ E + +LAPE L +D W G Sbjct 305 DFHLKISDFGLAKVIHGTGTFLETFCGTMGYLAPEVLKSKNVNLDGGYDDKVDIWSLGCV 364 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQ-----HRLPEPSCPQLATLTSQCLTYEPTQRPS 858 L + P S S ++ + L + L ++ L P +R S Sbjct 365 LY-VMLTASIPFASSSQAKCIELISKGAYPIEPLLENEISEEGIDLINRMLEINPEKRIS 423 Query 859 FRTILRDLTRLQPHNLADVLTVNPDSP 885 L+ + Sbjct 424 ESEALQHPWFYTVSTHEHRTPPSSSEH 450 >sp|Q9FJI4|LK111_ARATH Putative L-type lectin-domain containing receptor kinase I.11 OS=Arabidopsis thaliana OX=3702 GN=LECRK111 PE=3 SV=1 Length=675 Score = 222 bits (565), Expect = 7e-60, Method: Composition-based stats. Identities = 76/300 (25%), Positives = 124/300 (41%), Gaps = 20/300 (7%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 +P + K LG+G FG+V D +AVK + D Q Sbjct 331 YSPHRFSYKSLYKATNRFDKDGRLGKGGFGEVYRGNLPHVGD-----IAVKRVCHDA-KQ 384 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIG 996 + E+ + +L H +++ G C +GE L LV EY+ GSL YL + ++ Sbjct 385 GMKQFVAEVVTMGSLKHRNLVPLLGYCRRKGE--LLLVSEYMSNGSLDQYLFHREKPALS 442 Query 997 LAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 +Q L+ + I ++YLH Q +HRD+ A NV+LD++ ++GDFG+A+ G Sbjct 443 WSQRLVILKDIASALSYLHTGANQVVLHRDIKASNVMLDSEFNGRLGDFGMARFEDYGDS 502 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP--PTKFLEL 1111 + + APE L +DV++FGV + E +T P P++ L Sbjct 503 VPVT--AAVGTMGYMAPE-LTTMGTSTRTDVYAFGVLMLE-VTCGRRPLDPKIPSEKRHL 558 Query 1112 IGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 I + + ++ + V L C A RPT E +I + Sbjct 559 IKWVCDCWRRDSIVDAIDTRLGGQYSVEETVMVLKLGLICTNIVAESRPTMEQVIQYINQ 618 Score = 219 bits (557), Expect = 8e-59, Method: Composition-based stats. Identities = 62/277 (22%), Positives = 104/277 (38%), Gaps = 60/277 (22%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + LG+G VY G L G + +K + Sbjct 344 ATNRFDKDGRLGKGGFGEVYRGNLPHVGD-------------------------IAVKRV 378 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL-RRER 703 F M + H +L + G C R E ++V+EY+ +G LD +L RE+ Sbjct 379 CHDAKQGMKQFVAEVVTMGSLKHRNLVPLLGYCRRKGELLLVSEYMSNGSLDQYLFHREK 438 Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + + ++V+ + +ASALSYL N+ ++H ++ N++L +L D Sbjct 439 PALSWSQRLVILKDIASALSYLHTGANQVVLHRDIKASNVMLDSEFNG-------RLGDF 491 Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ ++ V + ++APE G ST D + FG +LE+ G PL Sbjct 492 GMARFEDYGDSVPVTAAVGTMGYMAPELTTMGT---STRTDVYAFGVLMLEV-TCGRRPL 547 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYE 852 + PSEK H + C + Sbjct 548 DPKIPSEKRHLIKW---------------VCDCWRRD 569 >sp|Q9P0L2|MARK1_HUMAN Serine/threonine-protein kinase MARK1 OS=Homo sapiens OX=9606 GN=MARK1 PE=1 SV=2 Length=795 Score = 224 bits (572), Expect = 7e-60, Method: Composition-based stats. Identities = 70/249 (28%), Positives = 110/249 (44%), Gaps = 13/249 (5%) Query 864 RDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGT 923 + + + ++ ++ H + + +G+G+F KV L + T Sbjct 27 PHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKL----ARHVLT 82 Query 924 GEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVP 982 G VAVK + K P +E+ I++ L H +I+K E EK+L LVMEY Sbjct 83 GREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIE--TEKTLYLVMEYAS 140 Query 983 LGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 G + DYL H + + +QI + Y H ++ +HRDL A N+LLD D +KI D Sbjct 141 GGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIAD 200 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDS 1100 FG + G++ + + APE + K+ DVWS GV LY L++ Sbjct 201 FGFSNEFTVGNKL----DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLP 256 Query 1101 SQSPPTKFL 1109 K L Sbjct 257 FDGQNLKEL 265 Score = 182 bits (463), Expect = 4e-46, Method: Composition-based stats. Identities = 62/354 (18%), Positives = 111/354 (31%), Gaps = 45/354 (13%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 QP ++S+ + R S + Q +G+G V R + G Sbjct 30 QPTKSSSRQNIPRCRNSITSATDEQPHIG-----NYRLQKTIGKGNFAKVKLARHVLTGR 84 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLA 671 V +K++D + + + +M ++H ++ Sbjct 85 ------------------------EVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIV 120 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 + V +V EY G + +L G + +Q+ SA+ Y K +V Sbjct 121 KLFEVIETEKTLYLVMEYASGGEVFDYLVAH-GRMKEKEARAKFRQIVSAVQYCHQKYIV 179 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGA 788 H ++ N+LL IK++D G + P+ APE G Sbjct 180 HRDLKAENLLLD-------GDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKK 232 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLTSQ 847 +D W G L + G P ++ E R +R+P L + Sbjct 233 YD-GPEVDVWSLGVILYTLVS-GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 290 Query 848 CLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901 L P +R S I++D H ++ P + T + Sbjct 291 LLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGF 344 >sp|O15865|CDPK2_PLAFK Calcium-dependent protein kinase 2 OS=Plasmodium falciparum (isolate K1 / Thailand) OX=5839 GN=CDPK2 PE=1 SV=3 Length=513 Score = 218 bits (555), Expect = 7e-60, Method: Composition-based stats. Identities = 68/333 (20%), Positives = 125/333 (38%), Gaps = 36/333 (11%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 + + T+ + + + LG+G +G V Sbjct 29 ENTSKQSNDYKYDINTSCISREGTTTLERKNLILCHSGKLEDKYIIDEKLGQGTYGCV-- 86 Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 Y + T ++ A+K K D ++ + + QEI+I++ L H +I+K E + Sbjct 87 --YKGIDKVTNQLYAIKEEKKD-RLKNINRFFQEIEIMKKLDHPNIVKLYETYE--NDNY 141 Query 974 LQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL- 1031 + L+ME L D + S +QI + YLH+ + +HRDL N L Sbjct 142 IYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNIVHRDLKPENFLFQ 201 Query 1032 --DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 + D L+KI DFGL+K + G ++ AP+ L + K+ D+WS GV Sbjct 202 SENKDSLLKIIDFGLSKNLGTGE----FTTTKAGTPYYVAPQVL-DGKYDKKCDIWSSGV 256 Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC---PCEVYH 1146 +Y LL T + + +++GE + + + Sbjct 257 IMYTLLCGYPPFYGD---------------TDNEVLKKVKKGEFCFYENDWGSISSDAKN 301 Query 1147 LMKNCWETEASFRPTFENLI--PILKTVHEKYQ 1177 L+ + R T E + P + + + ++ Sbjct 302 LITKLLTYNPNERCTIEEALNHPWITQMTKSHE 334 Score = 183 bits (464), Expect = 6e-48, Method: Composition-based stats. Identities = 49/300 (16%), Positives = 94/300 (31%), Gaps = 41/300 (14%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + + LGQGT VY+G D+ +K Sbjct 69 EDKYIIDEKLGQGTYGCVYKGI------------------------DKVTNQLYAIKEEK 104 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 F++ +M ++ H ++ ++ ++ E L + E G Sbjct 105 KDRLKNINRFFQEIEIMKKLDHPNIVKLYETYENDNYIYLIMELCSGRELFDSII-ENGS 163 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 + +Q+ SA+ YL + N+VH ++ N L +E +K+ D G+ Sbjct 164 FTEKNAATIMKQIFSAIFYLHSLNIVHRDLKPENFL----FQSENKDSLLKIIDFGLSKN 219 Query 766 ALS---REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + + ++AP+ L G D W G + + G P + +E Sbjct 220 LGTGEFTTTKAGTPYYVAPQVLDG---KYDKKCDIWSSGVIMYTLLC-GYPPFYGDTDNE 275 Query 823 KEHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 ++ L ++ LTY P +R + L Q + Sbjct 276 VLKKVKKGEFCFYENDWGSISSDAKNLITKLLTYNPNERCTIEEALNHPWITQMTKSHEH 335 >sp|Q8ICR0|CDPK2_PLAF7 Calcium-dependent protein kinase 2 OS=Plasmodium falciparum (isolate 3D7) OX=36329 GN=CDPK2 PE=1 SV=4 Length=513 Score = 218 bits (555), Expect = 7e-60, Method: Composition-based stats. Identities = 68/333 (20%), Positives = 125/333 (38%), Gaps = 36/333 (11%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 + + T+ + + + LG+G +G V Sbjct 29 ENTSKQSNDYKYDINTSCISREGTTTLERKNLILCHSGKLEDKYIIDEKLGQGTYGCV-- 86 Query 914 YCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKS 973 Y + T ++ A+K K D ++ + + QEI+I++ L H +I+K E + Sbjct 87 --YKGIDKVTNQLYAIKEEKKD-RLKNINRFFQEIEIMKKLDHPNIVKLYETYE--NDNY 141 Query 974 LQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL- 1031 + L+ME L D + S +QI + YLH+ + +HRDL N L Sbjct 142 IYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNIVHRDLKPENFLFQ 201 Query 1032 --DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGV 1089 + D L+KI DFGL+K + G ++ AP+ L + K+ D+WS GV Sbjct 202 SENKDSLLKIIDFGLSKNLGTGE----FTTTKAGTPYYVAPQVL-DGKYDKKCDIWSSGV 256 Query 1090 TLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC---PCEVYH 1146 +Y LL T + + +++GE + + + Sbjct 257 IMYTLLCGYPPFYGD---------------TDNEVLKKVKKGEFCFYENDWGSISSDAKN 301 Query 1147 LMKNCWETEASFRPTFENLI--PILKTVHEKYQ 1177 L+ + R T E + P + + + ++ Sbjct 302 LITKLLTYNPNERCTIEEALNHPWITQMTKSHE 334 Score = 183 bits (464), Expect = 6e-48, Method: Composition-based stats. Identities = 49/300 (16%), Positives = 94/300 (31%), Gaps = 41/300 (14%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + + LGQGT VY+G D+ +K Sbjct 69 EDKYIIDEKLGQGTYGCVYKGI------------------------DKVTNQLYAIKEEK 104 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 F++ +M ++ H ++ ++ ++ E L + E G Sbjct 105 KDRLKNINRFFQEIEIMKKLDHPNIVKLYETYENDNYIYLIMELCSGRELFDSII-ENGS 163 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 + +Q+ SA+ YL + N+VH ++ N L +E +K+ D G+ Sbjct 164 FTEKNAATIMKQIFSAIFYLHSLNIVHRDLKPENFL----FQSENKDSLLKIIDFGLSKN 219 Query 766 ALS---REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + + ++AP+ L G D W G + + G P + +E Sbjct 220 LGTGEFTTTKAGTPYYVAPQVLDG---KYDKKCDIWSSGVIMYTLLC-GYPPFYGDTDNE 275 Query 823 KEHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 ++ L ++ LTY P +R + L Q + Sbjct 276 VLKKVKKGEFCFYENDWGSISSDAKNLITKLLTYNPNERCTIEEALNHPWITQMTKSHEH 335 >sp|Q7Y0B9|SAPK8_ORYSJ Serine/threonine-protein kinase SAPK8 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK8 PE=1 SV=1 Length=371 Score = 213 bits (543), Expect = 7e-60, Method: Composition-based stats. Identities = 73/284 (26%), Positives = 122/284 (43%), Gaps = 26/284 (9%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 P + + +RD+G G+FG L + T E+VAVK + + G + + Sbjct 22 MDMPIMHDSDRYELVRDIGSGNFGVARLM----RDRRTMELVAVKYI--ERGEKIDDNVQ 75 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFA 1004 +EI R+L H +II++K L +VMEY G L + + ++ + F Sbjct 76 REIINHRSLKHPNIIRFKEVILTPTH--LAIVMEYASGGELFERICKNVRFSEDEARYFF 133 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 QQ+ G++Y H+ HRDL N LLD +KI DFG +K + + + Sbjct 134 QQLISGVSYCHSMQVCHRDLKLENTLLDGSPAPRLKICDFGYSK---SSVLHSQPKSTVG 190 Query 1063 SPVFWYAPECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 +P + APE L + ++ +DVWS GVTLY ++ + P + + Sbjct 191 TPA-YIAPEVLLKKEYDGKTADVWSCGVTLYVMVVGAYPFEDPE----------EPKNFR 239 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + +L +P E HL+ + + S R T + Sbjct 240 KTIQRILNVQYSIPENVDISPECRHLISRIFVGDPSLRITIPEI 283 Score = 154 bits (388), Expect = 3e-39, Method: Composition-based stats. Identities = 55/329 (17%), Positives = 97/329 (29%), Gaps = 41/329 (12%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 D + +G G RDR V +K + Sbjct 29 DSDRYELVRDIGSGNFG------------------------VARLMRDRRTMELVAVKYI 64 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + I + H ++ V + +V EY G L + + Sbjct 65 ERG-EKIDDNVQREIINHRSLKHPNIIRFKEVILTPTHLAIVMEYASGGELFERICKNV- 122 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 QQL S +SY + + H ++ N LL +P +K+ D G Sbjct 123 RFSEDEARYFFQQLISGVSYCHSMQVCHRDLKLENTLLD-----GSPAPRLKICDFGYSK 177 Query 765 GAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 ++ + V ++APE L T D W G TL + P Sbjct 178 SSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKT-ADVWSCGVTLYVMVVGAYPFEDPEEPK 236 Query 822 E----KEHFYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + Q+ +PE P+ L S+ +P+ R + I L+ Sbjct 237 NFRKTIQRILNVQYSIPENVDISPECRHLISRIFVGDPSLRITIPEIRSHGWFLKNLPAD 296 Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 + + S +P + + ++ L Sbjct 297 LMDDDSMSSQYEEPDQPMQTMDQIMQILT 325 >sp|Q8T0S6|HIPPO_DROME Serine/threonine-protein kinase hippo OS=Drosophila melanogaster OX=7227 GN=hpo PE=1 SV=1 Length=669 Score = 222 bits (565), Expect = 7e-60, Method: Composition-based stats. Identities = 64/279 (23%), Positives = 113/279 (41%), Gaps = 27/279 (10%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 ++ + LGEG +G V Y + + +VA+K + + +EI I Sbjct 36 QPPEKVFDIMYKLGEGSYGSV----YKAVHKESSSIVAIKLVPVESDLH---EIIKEISI 88 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY--LPRHSIGLAQLLLFAQQIC 1008 ++ ++++Y G Q + L + MEY GS+ D L + ++ ++ Sbjct 89 MQQCDSPYVVRYYGSYFKQYD--LWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTL 146 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +G+ YLH + IHRD+ A N+LL+ + K+ DFG+A + + R FW Sbjct 147 QGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMA---KRNTVIGTPFWM 203 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 APE ++E + +D+WS G+T E+ G + + + Sbjct 204 APEVIEEIGYDCVADIWSLGITALEMAEGKPPY-----------GEIHPMRAIFMIPQKP 252 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 R PD+ E + C E R T L+ Sbjct 253 PPSFR--EPDRWSTEFIDFVSKCLVKEPDDRATATELLE 289 Score = 191 bits (486), Expect = 1e-49, Method: Composition-based stats. Identities = 71/386 (18%), Positives = 126/386 (33%), Gaps = 61/386 (16%) Query 553 PQPGETSNLIIMRGARASPRTL-----NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 E ++++ M+ S LS+ S + +K + LG+G+ +VY+ Sbjct 1 MSEPEVTSVVDMKSPNISSSCSFFKLKKLSEESLLQPPEKVFDIMYKLGEGSYGSVYKAV 60 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSH 667 + S V +K L P D+ + S+M Q Sbjct 61 HKESSS------------------------IVAIK-LVPVESDLH-EIIKEISIMQQCDS 94 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 ++ +G + + + EY G + +R + + + L YL Sbjct 95 PYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHL 154 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----REERVERIPWLAPEC 783 + +H ++ NILL G + KL+D GV R + W+APE Sbjct 155 RRKIHRDIKAANILLNTEG-------YAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEV 207 Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ----HRLPEPSCP 839 + D W G T LE+ +G+ P P ++ R P+ Sbjct 208 IEE--IGYDCVADIWSLGITALEMA-EGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWST 264 Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899 + S+CL EP R + +L + + + + ++ A R Sbjct 265 EFIDFVSKCLVKEPDDRATATELLEHEFIRNAKHRSILKPMLEETCAIREQQRANR---- 320 Query 900 IRDLGEGHFGKVSLYCYDPTNDGTGE 925 FG V L + T E Sbjct 321 -------SFGGV-LAASQAKSLATQE 338 >sp|Q7XUN6|SIT2_ORYSJ L-type lectin-domain containing receptor kinase SIT2 OS=Oryza sativa subsp. japonica OX=39947 GN=SIT2 PE=2 SV=2 Length=673 Score = 222 bits (565), Expect = 7e-60, Method: Composition-based stats. Identities = 75/296 (25%), Positives = 119/296 (40%), Gaps = 16/296 (5%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 P + R LG G FG+V Y + VAVK + A Q Sbjct 337 PHRFSYKDLFHATDGFSDKRLLGIGGFGRV----YRGVLPSSKAEVAVKKV-AHGSRQGM 391 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLA 998 + E+ + L H ++++ G C +GE L LV +Y+P GSL L + ++ A Sbjct 392 REFVAEVVSIGRLRHRNLVQLLGYCRRKGE--LLLVYDYMPNGSLDKQLYDQGKITLRWA 449 Query 999 QLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 Q + + G+ YLH +HRD+ A NVLLD D ++GDFGLA+ G + + Sbjct 450 QRFRIIRGVASGLLYLHEDWEQVVVHRDIKASNVLLDADMNGRLGDFGLARLYDHGTDPH 509 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGI 1114 + + APE K ASDV++FG + E+ +Q + L+ Sbjct 510 TTH--VVGTMGYLAPELGHTGKASKASDVFAFGAFMLEVACGRKPVAQDARDNRVVLVDW 567 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + +T+ ++ + V L C RP L+ L+ Sbjct 568 VLDRWRAGAITDTVDPRLHGDFVESEASLVLRLGLLCSHPLPGARPGTRQLVQYLE 623 Score = 206 bits (524), Expect = 2e-54, Method: Composition-based stats. Identities = 66/352 (19%), Positives = 110/352 (31%), Gaps = 61/352 (17%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + LG G VY G L + V +K + Sbjct 348 ATDGFSDKRLLGIGGFGRVYRGVL------------------------PSSKAEVAVKKV 383 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE-R 703 F + ++ H +L + G C R E ++V +Y+ +G LD L + + Sbjct 384 AHGSRQGMREFVAEVVSIGRLRHRNLVQLLGYCRRKGELLLVYDYMPNGSLDKQLYDQGK 443 Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + A + + + +AS L YL + +VH ++ N+LL +L D Sbjct 444 ITLRWAQRFRIIRGVASGLLYLHEDWEQVVVHRDIKASNVLLD-------ADMNGRLGDF 496 Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ V + +LAPE G S A D + FGA +LE+ + Sbjct 497 GLARLYDHGTDPHTTHVVGTMGYLAPEL--GHTGKASKASDVFAFGAFMLEVACGRKPVA 554 Query 816 QSRSPSEKEHFYQRQHR-----LPEPSCPQLA------------TLTSQCLTYEPTQRPS 858 Q + R + + P+L L C P RP Sbjct 555 QDARDNRVVLVDWVLDRWRAGAITDTVDPRLHGDFVESEASLVLRLGLLCSHPLPGARPG 614 Query 859 FRTILRDLTRLQPHNL--ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 R +++ L P + N + D + G F Sbjct 615 TRQLVQYLEGDVPLPELSPTYQSFNMLALMQDQGFDPYVMSYPMTSTSAGTF 666 >sp|P0DP15|SNF1_FUSVI Sucrose non-fermenting protein kinase 1 OS=Fusarium virguliforme OX=232082 GN=SNF1 PE=3 SV=1 Length=698 Score = 222 bits (566), Expect = 8e-60, Method: Composition-based stats. Identities = 82/268 (31%), Positives = 119/268 (44%), Gaps = 31/268 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEIDILRTLYHEHI 959 LGEG FGKV L ++GTG+ VA+K + K ++EI+ L+ L H HI Sbjct 67 TLGEGSFGKVKL----AIHNGTGQQVALKIIARKKLISRDMAGRVEREIEYLQLLRHPHI 122 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018 IK + E + +V+EY G L DY+ +H + A+ F QQ+ + Y H Sbjct 123 IKLYTVIKTPNE--IIMVLEYA-GGELFDYIVQHGRMKEAEARRFFQQMLCAVEYCHRHK 179 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRDL N+LLD + VKI DFGL+ + +G+ ++ SP + APE + + Sbjct 180 IVHRDLKPENLLLDENLNVKIADFGLSNIMTDGN---FLKTSCGSPN-YAAPEVIGGKLY 235 Query 1079 -YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 DVWS GV LY LL L IA+G + P Sbjct 236 AGPEVDVWSCGVILYVLLVGRLPFDDEHIPSL-FAKIAKGTYS---------------IP 279 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165 P +L+K R T E++ Sbjct 280 QWMPLGAANLIKKMLVVNPVHRATIEDI 307 Score = 174 bits (442), Expect = 5e-44, Method: Composition-based stats. Identities = 56/306 (18%), Positives = 98/306 (32%), Gaps = 36/306 (12%) Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 G+R + L + R+ ++ L LG+G+ V G + Sbjct 41 GSRPADAPLKERIKTEQRIGAYKV--LRTLGEGSFGKVKLAIHNGTGQQVALKI------ 92 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 + K L + + + H H+ ++ V E IM Sbjct 93 -------------IARKKLISRDMAGRVE--REIEYLQLLRHPHIIKLYTVIKTPNEIIM 137 Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 V EY G L ++ + G + A QQ+ A+ Y +VH ++ N+LL Sbjct 138 VLEYA-GGELFDYI-VQHGRMKEAEARRFFQQMLCAVEYCHRHKIVHRDLKPENLLLDE- 194 Query 746 GLAEGTSPFIKLSDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 + +K++D G+ + + APE + GG +D W G Sbjct 195 ------NLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVI-GGKLYAGPEVDVWSCGV 247 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 L + PS + + +P+ A L + L P R + I Sbjct 248 ILYVLLVGRLPFDDEHIPSLFAKIAKGTYSIPQWMPLGAANLIKKMLVVNPVHRATIEDI 307 Query 863 LRDLTR 868 D Sbjct 308 RADPWF 313 >sp|Q9LMN6|WAK4_ARATH Wall-associated receptor kinase 4 OS=Arabidopsis thaliana OX=3702 GN=WAK4 PE=2 SV=1 Length=738 Score = 223 bits (568), Expect = 8e-60, Method: Composition-based stats. Identities = 75/344 (22%), Positives = 129/344 (38%), Gaps = 24/344 (7%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTR------LQPHNLADVLTVNPDSPASDPTVFHKRYL 897 L C+ ++ + + +Q + A V+ + Sbjct 351 LAISCIEHKMKNTKDTELRQQFFEQNGGGMLMQRLSGAGPSNVDVKIFTEEGMKEATDGY 410 Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 + R LG+G G V +VA+K + Q + E+ +L + H Sbjct 411 DENRILGQGGQGTVYKGIL-----PDNSIVAIKKARLGDNSQ-VEQFINEVLVLSQINHR 464 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAY 1013 +++K GCC + E L LV E++ G+L D+L S+ L A +I +AY Sbjct 465 NVVKLLGCCLE-TEVPL-LVYEFISSGTLFDHLHGSMFDSSLTWEHRLRMAVEIAGTLAY 522 Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 LH+ IHRD+ N+LLD + K+ DFG ++ +P E G + + P Sbjct 523 LHSSASIPIIHRDIKTANILLDENLTAKVADFGASRLIPMDKEDLATMVQG--TLGYLDP 580 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E SDV+SFGV L ELL+ + P ++ RL E+++ Sbjct 581 EYYNTGLLNEKSDVYSFGVVLMELLSGQKALCFERPQTSKHIVSYFASATKENRLHEIID 640 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + + + C RP + + L+ + Sbjct 641 GQVMNENNQREIQKAARIAVECTRLTGEERPGMKEVAAELEALR 684 Score = 205 bits (522), Expect = 6e-54, Method: Composition-based stats. Identities = 62/361 (17%), Positives = 124/361 (34%), Gaps = 63/361 (17%) Query 559 SNLIIMRGARASPRTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDP 616 +++ R + A P +++ + + + LGQG + VY+G L Sbjct 378 GGMLMQRLSGAGPSNVDVKIFTEEGMKEATDGYDENRILGQGGQGTVYKGILPDNSI--- 434 Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676 V +K + F ++SQ++H ++ + G Sbjct 435 ----------------------VAIKKARLGDNSQVEQFINEVLVLSQINHRNVVKLLGC 472 Query 677 CVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLV 731 C+ ++V E++ G L L + W ++ +A ++A L+YL + ++ Sbjct 473 CLETEVPLLVYEFISSGTLFDHLHGSMFDSSLTWEHRLRMAVEIAGTLAYLHSSASIPII 532 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-----RVERIPWLAPECLPG 786 H ++ NILL + K++D G +E + +L PE Sbjct 533 HRDIKTANILLDE-------NLTAKVADFGASRLIPMDKEDLATMVQGTLGYLDPEYYNT 585 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-----RQHRLPEPSCPQL 841 G L+ D + FG L+E+ +A R + K +++RL E Q+ Sbjct 586 GL--LNEKSDVYSFGVVLMELLSGQKALCFERPQTSKHIVSYFASATKENRLHEIIDGQV 643 Query 842 ------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 A + +C +RP + + +L L+ + Sbjct 644 MNENNQREIQKAARIAVECTRLTGEERPGMKEVAAELEALRVTKTKHKWSDEYPEQEDTE 703 Query 890 T 890 Sbjct 704 H 704 >sp|P27636|CDC15_YEAST Cell division control protein 15 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CDC15 PE=1 SV=3 Length=974 Score = 227 bits (578), Expect = 8e-60, Method: Composition-based stats. Identities = 72/274 (26%), Positives = 112/274 (41%), Gaps = 31/274 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 + +G G +G V Y N T ++VA+K + + + + EI +L+ L Sbjct 24 QYHLKQVIGRGSYGVV----YKAINKHTDQVVAIKEVVYE-NDEELNDIMAEISLLKNLN 78 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAY 1013 H +I+KY G E L +++EY GSLR + R S + + + Q G+ Y Sbjct 79 HNNIVKYHGFIRKSYE--LYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKY 136 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 LH + IHRD+ A N+LL D VK+ DFG++ V + W APE L Sbjct 137 LHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSAL------TLAGTLNWMAPEIL 190 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 SD+WS G T+ E+LT +T + +E Sbjct 191 GNRGASTLSDIWSLGATVVEMLTKNPP---------------YHNLTDANIYYAVENDTY 235 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P P + + C+ RPT + L+ Sbjct 236 YP-PSSFSEPLKDFLSKCFVKNMYKRPTADQLLK 268 Score = 199 bits (505), Expect = 9e-51, Method: Composition-based stats. Identities = 57/304 (19%), Positives = 108/304 (36%), Gaps = 36/304 (12%) Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 + A +NL+ + + +G+G+ VY+ Sbjct 2 NSMADTDRVNLTPIQRASEKSVQYHLKQVIGRGSYGVVYKAI------------------ 43 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIM 685 ++ + V +K + + + SL+ ++H ++ HG + E + Sbjct 44 ------NKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYI 97 Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 + EY +G L + R + Q L YL + ++H ++ NILL+ Sbjct 98 LLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSAD 157 Query 746 GLAEGTSPFIKLSDPGVGLGALSRE-ERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 +KL+D GV S + W+APE L G ST D W GAT+ Sbjct 158 N-------TVKLADFGVSTIVNSSALTLAGTLNWMAPEIL--GNRGASTLSDIWSLGATV 208 Query 805 LEICFDGEAPLQSRSPSEKEH-FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 +E+ P + + + + + P L S+C +RP+ +L Sbjct 209 VEMLTK-NPPYHNLTDANIYYAVENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLL 267 Query 864 RDLT 867 + + Sbjct 268 KHVW 271 >sp|P09560|RAF1_XENLA RAF proto-oncogene serine/threonine-protein kinase OS=Xenopus laevis OX=8355 GN=raf1 PE=2 SV=1 Length=638 Score = 221 bits (563), Expect = 8e-60, Method: Composition-based stats. Identities = 77/297 (26%), Positives = 130/297 (44%), Gaps = 27/297 (9%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHR 941 +S + +G G FG V + VAVK LK D P+ Sbjct 326 QRDSSYYWEIIASEVMLSSRIGSGSFGTVYKGKWHG-------DVAVKILKVTDPTPEQL 378 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQ 999 ++ E+ +LR H +I+ + G + +L +V ++ SL +L + Q Sbjct 379 QAFRNEVAVLRKTRHVNILLFMGYM---TKDNLAIVTQWCEGSSLYYHLHVLDTKFQMFQ 435 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 L+ A+Q +GM YLHA++ IHRD+ + N+ L VKIGDFGLA +V E Sbjct 436 LIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKTRWSGSQQV-E 494 Query 1060 DGDSPVFWYAPECLK---EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 + W APE ++ F + SDV+S+G+ LYEL+T + + + + Sbjct 495 QLTGSILWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHIRDRDQIIFLVGR 554 Query 1117 GQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 G + V L++L + CP + L+ + + RP F ++ ++ + Sbjct 555 GGV-VPDLSKLYK---------NCPKAMKRLVADSIKKLRDERPLFPQILSSIELLQ 601 Score = 211 bits (538), Expect = 1e-56, Method: Composition-based stats. Identities = 63/310 (20%), Positives = 108/310 (35%), Gaps = 57/310 (18%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 R G+ N I RG R S + + E+ S +G G+ VY+G+ Sbjct 307 REKAASSTGQEKNKIRARGQRDSSY--------YWEIIASEVMLSSRIGSGSFGTVYKGK 358 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH--DIALAFYETASLMSQV 665 + V +K+L + + AF +++ + Sbjct 359 WHGD---------------------------VAVKILKVTDPTPEQLQAFRNEVAVLRKT 391 Query 666 SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL 725 H ++ G + +VT++ E L L M + +A+Q A + YL Sbjct 392 RHVNILLFMGYMTK-DNLAIVTQWCEGSSLYYHLHVLDTKFQMFQLIDIARQTAQGMDYL 450 Query 726 ENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWL 779 KN++H ++ NI L +K+ D G+ G+ E+ I W+ Sbjct 451 HAKNIIHRDMKSNNIFLHEGL-------TVKIGDFGLATVKTRWSGSQQVEQLTGSILWM 503 Query 780 APECLPGGA-NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838 APE + N S D + +G L E+ GE P ++ F + Sbjct 504 APEVIRMQDNNPFSFQSDVYSYGIVLYELM-TGELPYSHIRDRDQIIFLVGRG----GVV 558 Query 839 PQLATLTSQC 848 P L+ L C Sbjct 559 PDLSKLYKNC 568 >sp|Q9LMN8|WAK3_ARATH Wall-associated receptor kinase 3 OS=Arabidopsis thaliana OX=3702 GN=WAK3 PE=2 SV=2 Length=741 Score = 223 bits (568), Expect = 9e-60, Method: Composition-based stats. Identities = 78/344 (23%), Positives = 133/344 (39%), Gaps = 24/344 (7%) Query 844 LTSQCLTYEPTQRPSFRTILRDLTR------LQPHNLADVLTVNPDSPASDPTVFHKRYL 897 L + C+ + QR + + + +Q + A + ++ + Sbjct 356 LAAICIQHATKQRKYTKLRRQFFEQNGGGMLIQRLSGAGLSNIDFKIFTEEGMKEATNGY 415 Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 + R LG+G G V +VA+K + + + E+ +L + H Sbjct 416 DESRILGQGGQGTVYKGIL-----PDNTIVAIKKARL-ADSRQVDQFIHEVLVLSQINHR 469 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAY 1013 +++K GCC + E L LV E++ G+L D+L S+ L A ++ +AY Sbjct 470 NVVKILGCCLE-TEVPL-LVYEFITNGTLFDHLHGSIFDSSLTWEHRLRIAIEVAGTLAY 527 Query 1014 LHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 LH+ IHRD+ N+LLD + K+ DFG +K +P E G + + P Sbjct 528 LHSSASIPIIHRDIKTANILLDENLTAKVADFGASKLIPMDKEQLTTMVQG--TLGYLDP 585 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E SDV+SFGV L ELL+ + P L+ RL E+++ Sbjct 586 EYYTTGLLNEKSDVYSFGVVLMELLSGQKALCFERPQASKHLVSYFVSATEENRLHEIID 645 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 K E + C RP + + L+ + Sbjct 646 DQVLNEDNLKEIQEAARIAAECTRLMGEERPRMKEVAAKLEALR 689 Score = 202 bits (514), Expect = 7e-53, Method: Composition-based stats. Identities = 68/387 (18%), Positives = 128/387 (33%), Gaps = 61/387 (16%) Query 547 LRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEG 606 LRR Q G + + GA S + + + LGQG + VY+G Sbjct 373 LRRQFFEQNGGGMLIQRLSGAGLSNIDFKIFTEEGMKEATNGYDESRILGQGGQGTVYKG 432 Query 607 RLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS 666 L V +K + F ++SQ++ Sbjct 433 ILPDN-------------------------TIVAIKKARLADSRQVDQFIHEVLVLSQIN 467 Query 667 HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE--RGHVPMAWKMVVAQQLASALSY 724 H ++ + G C+ ++V E++ +G L L + ++ +A ++A L+Y Sbjct 468 HRNVVKILGCCLETEVPLLVYEFITNGTLFDHLHGSIFDSSLTWEHRLRIAIEVAGTLAY 527 Query 725 LENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----ERI 776 L + ++H ++ NILL + K++D G +E++ + Sbjct 528 LHSSASIPIIHRDIKTANILLDE-------NLTAKVADFGASKLIPMDKEQLTTMVQGTL 580 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ-----RQH 831 +L PE G L+ D + FG L+E+ +A R + K ++ Sbjct 581 GYLDPEYYTTGL--LNEKSDVYSFGVVLMELLSGQKALCFERPQASKHLVSYFVSATEEN 638 Query 832 RLPEPSCPQL------------ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 RL E Q+ A + ++C +RP + + L L+ + Sbjct 639 RLHEIIDDQVLNEDNLKEIQEAARIAAECTRLMGEERPRMKEVAAKLEALRVEKTKHKWS 698 Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEG 906 H + G Sbjct 699 DQYPEENEHLIGGHILSAQGETSSSIG 725 >sp|Q68UT7|HUNK_PANTR Hormonally up-regulated neu tumor-associated kinase OS=Pan troglodytes OX=9598 GN=HUNK PE=3 SV=1 Length=714 Score = 223 bits (567), Expect = 9e-60, Method: Composition-based stats. Identities = 75/306 (25%), Positives = 121/306 (40%), Gaps = 25/306 (8%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 YL R LGEG F KV + + TGE VA+K + + Sbjct 45 PRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVR----EGLHVLTGEKVAIKVIDKKRAKK 100 Query 940 HR---SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSI 995 ++E I + + H +I + E E S LVME P G+L + + + Sbjct 101 DTYVTKNLRREGQIQQMIRHPNITQLLDILE--TENSYYLVMELCPGGNLMHKIYEKKRL 158 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 ++ + +Q+ + +LH +HRDL N+LLD D +K+ DFGL+ Sbjct 159 EESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSD 218 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 SP + APE L K+ DVWS GV +Y +LT P Sbjct 219 PFSTQCGSPA-YAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPF--------- 268 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 ++ L + + E P P + +++ E + RP + + + ++E Sbjct 269 ----SLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALAN-RWLNEN 323 Query 1176 YQGQAP 1181 Y G+ P Sbjct 324 YTGKVP 329 Score = 162 bits (410), Expect = 7e-40, Method: Composition-based stats. Identities = 58/344 (17%), Positives = 106/344 (31%), Gaps = 49/344 (14%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L H+ + LG+G+ V EG + G Sbjct 49 LRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGE---------------------- 86 Query 636 ELRVVLKVLDPSHHD----IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +V +KV+D + + + H ++ + + +V E Sbjct 87 --KVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCP 144 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G L + E+ + + +QL SA+ +L +VH ++ N+LL Sbjct 145 GGNLMHKIY-EKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDN----- 198 Query 752 SPFIKLSDPGV----GLGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 IKL D G+ G+ S + + APE L +D W G + Sbjct 199 --NIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA--RKKYGPKIDVWSIGVNMY 254 Query 806 EICFDGEAPL----QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861 + G P S ++ + + LP + L +P +RP+ + Sbjct 255 AML-TGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQ 313 Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 L + + + V + S + L LG Sbjct 314 ALANRWLNENYTGKVPCNVTYPNRISLEDLSPSVVLHMTEKLGY 357 >sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo sapiens OX=9606 GN=SIK2 PE=1 SV=1 Length=926 Score = 226 bits (576), Expect = 9e-60, Method: Composition-based stats. Identities = 72/291 (25%), Positives = 112/291 (38%), Gaps = 29/291 (10%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADC 936 + + + LG+G+F V L + T VA+K + K+ Sbjct 1 MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLG----RHRITKTEVAIKIIDKSQL 56 Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SI 995 + +E+ I++ L H HIIK E + L LV EY G + DYL H + Sbjct 57 DAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKS--MLYLVTEYAKNGEIFDYLANHGRL 114 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 ++ QI + Y H + +HRDL A N+LLDN+ +KI DFG G Sbjct 115 NESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGE--- 171 Query 1056 RVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + + APE + ++ D+WS GV LY L+ P Sbjct 172 -LLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGP---------- 220 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 T+ L + + G R P + HL++ + S R T + Sbjct 221 -----TLPILRQRVLEG-RFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQI 265 Score = 195 bits (496), Expect = 8e-50, Method: Composition-based stats. Identities = 64/323 (20%), Positives = 110/323 (34%), Gaps = 43/323 (13%) Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 PR L + RV +I LG+G V GR R+ Sbjct 7 PRHLQRGPV---RVGFYDIE--GTLGKGNFAVVKLGRHRI-------------------- 41 Query 631 RDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 + V +K++D S D Y +M + H H+ ++ V +VTE Sbjct 42 ----TKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTE 97 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 Y ++G + +L G + + Q+ SA+ Y + +VH ++ N+LL Sbjct 98 YAKNGEIFDYLANH-GRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDN---- 152 Query 749 EGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + IK++D G G S E P+ APE G +D W G L Sbjct 153 ---NMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYE-GPQLDIWSMGVVLY 208 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + P ++ + + R+P L + L +P++R + I Sbjct 209 VLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEH 268 Query 866 LTRLQPHNLADVLTVNPDSPASD 888 L + + + Sbjct 269 KWMLIEVPVQRPVLYPQEQENEP 291 >sp|P57058|HUNK_HUMAN Hormonally up-regulated neu tumor-associated kinase OS=Homo sapiens OX=9606 GN=HUNK PE=1 SV=1 Length=714 Score = 223 bits (567), Expect = 9e-60, Method: Composition-based stats. Identities = 75/306 (25%), Positives = 121/306 (40%), Gaps = 25/306 (8%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 YL R LGEG F KV + + TGE VA+K + + Sbjct 45 PRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVR----EGLHVLTGEKVAIKVIDKKRAKK 100 Query 940 HR---SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSI 995 ++E I + + H +I + E E S LVME P G+L + + + Sbjct 101 DTYVTKNLRREGQIQQMIRHPNITQLLDILE--TENSYYLVMELCPGGNLMHKIYEKKRL 158 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 ++ + +Q+ + +LH +HRDL N+LLD D +K+ DFGL+ Sbjct 159 EESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSD 218 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 SP + APE L K+ DVWS GV +Y +LT P Sbjct 219 PFSTQCGSPA-YAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPF--------- 268 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEK 1175 ++ L + + E P P + +++ E + RP + + + ++E Sbjct 269 ----SLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALAN-RWLNEN 323 Query 1176 YQGQAP 1181 Y G+ P Sbjct 324 YTGKVP 329 Score = 162 bits (410), Expect = 7e-40, Method: Composition-based stats. Identities = 58/344 (17%), Positives = 106/344 (31%), Gaps = 49/344 (14%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L H+ + LG+G+ V EG + G Sbjct 49 LRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGE---------------------- 86 Query 636 ELRVVLKVLDPSHHD----IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +V +KV+D + + + H ++ + + +V E Sbjct 87 --KVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCP 144 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G L + E+ + + +QL SA+ +L +VH ++ N+LL Sbjct 145 GGNLMHKIY-EKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDN----- 198 Query 752 SPFIKLSDPGV----GLGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 IKL D G+ G+ S + + APE L +D W G + Sbjct 199 --NIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA--RKKYGPKIDVWSIGVNMY 254 Query 806 EICFDGEAPL----QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861 + G P S ++ + + LP + L +P +RP+ + Sbjct 255 AML-TGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQ 313 Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 L + + + V + S + L LG Sbjct 314 ALANRWLNENYTGKVPCNVTYPNRISLEDLSPSVVLHMTEKLGY 357 >sp|Q8NJT7|HOG1_HORWE Mitogen-activated protein kinase HOG1 OS=Hortaea werneckii OX=91943 GN=HOG1 PE=3 SV=1 Length=359 Score = 213 bits (541), Expect = 9e-60, Method: Composition-based stats. Identities = 66/276 (24%), Positives = 108/276 (39%), Gaps = 29/276 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VAVK + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SAKDQLTSQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + +V E + L L + + F QI G+ Y+H+ Sbjct 80 ICLSDIFISPLED-MYVVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIATICSENTLRFVQ 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFR 1159 L + ER P + + L++ + R Sbjct 252 SLPKRERQPLKNKFKNADPQAIELLERMLVFDPRKR 287 Score = 134 bits (336), Expect = 1e-32, Method: Composition-based stats. Identities = 41/252 (16%), Positives = 83/252 (33%), Gaps = 21/252 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + +D+ V +K ++ P ++ Y Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSAKDQLTSQAVAVKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + +VTE + L L + + Sbjct 67 ELKLLKHLRHENIICLSDIFISPLEDMYVVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 + APE + +D W G E+ +G+ + F L Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDH--VNQFSIITELLGT 232 Query 836 PSCPQLATLTSQ 847 P +AT+ S+ Sbjct 233 PPDDVIATICSE 244 >sp|Q63572|TESK1_RAT Dual specificity testis-specific protein kinase 1 OS=Rattus norvegicus OX=10116 GN=Tesk1 PE=1 SV=1 Length=628 Score = 220 bits (561), Expect = 1e-59, Method: Composition-based stats. Identities = 73/290 (25%), Positives = 123/290 (42%), Gaps = 28/290 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +G G F +V Y + +G+++ LK + P +RS +E+ ++ L H Sbjct 52 FDCAEKIGAGFFSEV----YKVRHRQSGQVM---VLKMNKLPSNRSNTLREVQLMNRLRH 104 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLH 1015 +I+++ G C QG+ L + EY+ G+L L + L A I +G+ YLH Sbjct 105 PNILRFMGVCVHQGQ--LHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIAQGLRYLH 162 Query 1016 AQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVRE-DGDSPVFWYAPE 1071 A+ HRDL ++N L+ D +GDFGLA+ +P E R +W APE Sbjct 163 AKGVFHRDLTSKNCLVRREDGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPE 222 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 L+ + +DV++FG+ L EL+ + + + T++ Sbjct 223 VLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVG-------- 274 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 + CP L +C E S R F + L+ + E+ P Sbjct 275 ------NDCPLPFLLLAIHCCSMEPSARAPFTEITQHLEQILEQLPEPTP 318 Score = 192 bits (488), Expect = 3e-50, Method: Composition-based stats. Identities = 69/311 (22%), Positives = 113/311 (36%), Gaps = 45/311 (14%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 +S R L + S RVD + +G G + VY+ R R G Sbjct 34 SSYRALRSAVSSLARVD--DFDCAEKIGAGFFSEVYKVRHRQSG---------------- 75 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 +V++ ++ + + LM+++ H ++ GVCV + +TE Sbjct 76 ---------QVMVLKMNKLPSNRSNT-LREVQLMNRLRHPNILRFMGVCVHQGQLHALTE 125 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 Y+ G L+ L + ++ +A +A L YL K + H ++ +N L+ R Sbjct 126 YMNGGTLEQLLSSPE-PLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRR---- 180 Query 749 EGTSPFIKLSDPGVG-LGALSREER-------VERIPWLAPECLPGGANSLSTAMDKWGF 800 E + D G+ + RE V W+APE L G D + F Sbjct 181 EDGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGEL--YDEKADVFAF 238 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-LPEPSCP-QLATLTSQCLTYEPTQRPS 858 G L E+ A +E R L CP L C + EP+ R Sbjct 239 GIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSARAP 298 Query 859 FRTILRDLTRL 869 F I + L ++ Sbjct 299 FTEITQHLEQI 309 >sp|P0CP68|HOG1_CRYNJ Mitogen-activated protein kinase HOG1 OS=Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) OX=214684 GN=HOG1 PE=1 SV=1 Length=365 Score = 213 bits (541), Expect = 1e-59, Method: Composition-based stats. Identities = 64/282 (23%), Positives = 106/282 (38%), Gaps = 31/282 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + +G VA+K + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SAKDQLSGTSVAIKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGIAQGQMTVL 1122 A D+WS G E+L +PP ++ I V Sbjct 192 DVAVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTIASENTLRFVQ 251 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 L + + P+ P + L++ + R + Sbjct 252 SLPKREKVPFSTKFPNADPVSL-DLLEKMLVFDPRTRISAAE 292 Score = 139 bits (349), Expect = 3e-34, Method: Composition-based stats. Identities = 37/231 (16%), Positives = 77/231 (33%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 V+E D + M + +D+ V +K ++ P ++ Y Sbjct 10 FGTVFE---VTTRYVDLQPVGMGAFGLVCSAKDQLSGTSVAIKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + A+D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVAVDIWSTGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q56R42|HOG1_CRYNH Mitogen-activated protein kinase HOG1 OS=Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) OX=235443 GN=HOG1 PE=1 SV=1 Length=365 Score = 213 bits (541), Expect = 1e-59, Method: Composition-based stats. Identities = 64/282 (23%), Positives = 106/282 (38%), Gaps = 31/282 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + +G VA+K + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SAKDQLSGTSVAIKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGIAQGQMTVL 1122 A D+WS G E+L +PP ++ I V Sbjct 192 DVAVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTIASENTLRFVQ 251 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 L + + P+ P + L++ + R + Sbjct 252 SLPKREKVPFSTKFPNADPVSL-DLLEKMLVFDPRTRISAAE 292 Score = 139 bits (349), Expect = 3e-34, Method: Composition-based stats. Identities = 37/231 (16%), Positives = 77/231 (33%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 V+E D + M + +D+ V +K ++ P ++ Y Sbjct 10 FGTVFE---VTTRYVDLQPVGMGAFGLVCSAKDQLSGTSVAIKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + A+D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVAVDIWSTGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|P0CP69|HOG1_CRYNB Mitogen-activated protein kinase HOG1 OS=Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) OX=283643 GN=HOG1 PE=3 SV=1 Length=365 Score = 213 bits (541), Expect = 1e-59, Method: Composition-based stats. Identities = 64/282 (23%), Positives = 106/282 (38%), Gaps = 31/282 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + +G VA+K + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SAKDQLSGTSVAIKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGIAQGQMTVL 1122 A D+WS G E+L +PP ++ I V Sbjct 192 DVAVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTIASENTLRFVQ 251 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 L + + P+ P + L++ + R + Sbjct 252 SLPKREKVPFSTKFPNADPVSL-DLLEKMLVFDPRTRISAAE 292 Score = 139 bits (349), Expect = 3e-34, Method: Composition-based stats. Identities = 37/231 (16%), Positives = 77/231 (33%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 V+E D + M + +D+ V +K ++ P ++ Y Sbjct 10 FGTVFE---VTTRYVDLQPVGMGAFGLVCSAKDQLSGTSVAIKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + A+D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVAVDIWSTGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q13546|RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 OS=Homo sapiens OX=9606 GN=RIPK1 PE=1 SV=3 Length=671 Score = 221 bits (564), Expect = 1e-59, Method: Composition-based stats. Identities = 81/289 (28%), Positives = 124/289 (43%), Gaps = 38/289 (13%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG-PQHRSGWKQEIDILRTLYHEHII 960 +L G FGKVSL + T ++ +K + +H +E ++ L H ++ Sbjct 22 ELDSGGFGKVSLCFHR-----TQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVV 76 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 K G ++G+ S LVMEY+ G+L L S L+ +I EGM YLH + Sbjct 77 KLLGVIIEEGKYS--LVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMCYLHGKGV 134 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKA----------VPEGHEYYRVREDGDSPVFWYA 1069 IH+DL N+L+DND +KI D GLA E E + +++ A Sbjct 135 IHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMA 194 Query 1070 PECLKE--YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 PE L + K SDV+SF V L+ + + + + + +L Sbjct 195 PEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPY--------------ENAICEQQLIMC 240 Query 1128 LERGERLPRPD---KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 ++ G R D CP E+ LMK CWE RPTF + + + Sbjct 241 IKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFY 289 Score = 189 bits (480), Expect = 7e-49, Method: Composition-based stats. Identities = 53/315 (17%), Positives = 108/315 (34%), Gaps = 53/315 (17%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 L+ ++ + + + L G V R +G + Sbjct 6 SLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKG--------------- 50 Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 P+ + A E A +M+++ H+ + + GV + + +V EY+E G L Sbjct 51 --------PNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMH 102 Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 L+ E P++ K + ++ + YL K ++H ++ NIL+ IK+ Sbjct 103 VLKAEM-STPLSVKGRIILEIIEGMCYLHGKGVIHKDLKPENILVDN-------DFHIKI 154 Query 758 SDPGVGLGAL-----------------SREERVERIPWLAPECLPGGANSLSTAMDKWGF 800 +D G+ + + ++ + ++APE L + D + F Sbjct 155 ADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSF 214 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-----LPEPSCPQLATLTSQCLTYEPTQ 855 L I + E + + + +R + E ++ +L C P Sbjct 215 AVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEYCPREIISLMKLCWEANPEA 274 Query 856 RPSFRTILRDLTRLQ 870 RP+F I Sbjct 275 RPTFPGIEEKFRPFY 289 >sp|F1NBT0|STK10_CHICK Serine/threonine-protein kinase 10 OS=Gallus gallus OX=9031 GN=STK10 PE=3 SV=2 Length=969 Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats. Identities = 74/299 (25%), Positives = 127/299 (42%), Gaps = 30/299 (10%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD 935 + + + + + +LG+G FGKV Y N TG + A K ++ Sbjct 15 FEKRRSKEYEHVRRDLDPGEVWEVVGELGDGAFGKV----YKAKNKETGALAAAKVIETK 70 Query 936 CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--H 993 + EI+IL T H HI+K G +G+ L +++E+ P G++ + Sbjct 71 -NEDELEDYMVEIEILATCDHPHIVKLLGAFYWEGK--LWIMIEFCPGGAVDATMLELDR 127 Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + Q+ + +Q+ E + YLH++ IHRDL A NVLL D +K+ DFG++ + + Sbjct 128 GLTEPQIQVICRQMLEALHYLHSKKIIHRDLKAGNVLLTQDGDIKLADFGVS---AKNVK 184 Query 1054 YYRVREDGDSPVFWYAPEC-----LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 + R+ +W APE +K+ + Y +D+WS G+TL E+ + Sbjct 185 TLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMA-QIEPPHHELNPM 243 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L+ IA+ L P K E +K + RP+ L+ Sbjct 244 RVLLKIAKSDPPT------------LSCPSKWSLEFRDFLKTALDKNPETRPSAAQLLE 290 Score = 184 bits (467), Expect = 3e-46, Method: Composition-based stats. Identities = 54/285 (19%), Positives = 95/285 (33%), Gaps = 43/285 (15%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LG G VY+ + + G+ KV++ + D Sbjct 41 ELGDGAFGKVYKAKNKETGA------------------------LAAAKVIETKNEDELE 76 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 + +++ H H+ + G + ++ E+ G +D + + V Sbjct 77 DYMVEIEILATCDHPHIVKLLGAFYWEGKLWIMIEFCPGGAVDATMLELDRGLTEPQIQV 136 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LGALSR 769 + +Q+ AL YL +K ++H ++ N+LL + G IKL+D GV R Sbjct 137 ICRQMLEALHYLHSKKIIHRDLKAGNVLLTQDGD-------IKLADFGVSAKNVKTLQKR 189 Query 770 EERVERIPWLAPECLP---GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + + W+APE + D W G TL+E+ E P +P Sbjct 190 DSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMA-QIEPPHHELNPMRVLLK 248 Query 827 YQRQHR----LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P + L P RPS +L Sbjct 249 IAKSDPPTLSCPSKWSLEFRDFLKTALDKNPETRPSAAQLLEHPF 293 >sp|Q8LPS5|SERK5_ARATH Somatic embryogenesis receptor kinase 5 OS=Arabidopsis thaliana OX=3702 GN=SERK5 PE=1 SV=2 Length=601 Score = 219 bits (559), Expect = 1e-59, Method: Composition-based stats. Identities = 67/323 (21%), Positives = 123/323 (38%), Gaps = 20/323 (6%) Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918 R + + +V + + K LG+G FG + Sbjct 237 RRKLQGHFLDVPAEEDPEVYLGQFKRFSLRELLVATEKFSKRNVLGKGRFGILYKGRL-- 294 Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978 +VAVK L + ++ E++++ H ++++ +G C E+ LV Sbjct 295 ---ADDTLVAVKRLNEERTKGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTER--LLVY 349 Query 979 EYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVL 1030 Y+ GS+ L + + A G+AYLH IH D+ A N+L Sbjct 350 PYMANGSVASCLRERPEGNPALDWPKRKHIALGSARGLAYLHDHCDQKIIHLDVKAANIL 409 Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 LD + +GDFGLAK + + V + APE L K +DV+ +GV Sbjct 410 LDEEFEAVVGDFGLAKLMNYNDSH--VTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGVM 467 Query 1091 LYELLTHCDSS---QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 L EL+T + + + L+ + + +L L++ + ++ + Sbjct 468 LLELITGQKAFDLARLANDDDIMLLDWVKEVLKEKKLESLVDAELEGKYVETEVEQLIQM 527 Query 1148 MKNCWETEASFRPTFENLIPILK 1170 C ++ A RP ++ +L+ Sbjct 528 ALLCTQSSAMERPKMSEVVRMLE 550 Score = 181 bits (459), Expect = 1e-46, Method: Composition-based stats. Identities = 68/352 (19%), Positives = 129/352 (37%), Gaps = 52/352 (15%) Query 575 NLSQLSFHR--VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 + S V ++ ++ + LG+G +Y+GRL Sbjct 259 QFKRFSLRELLVATEKFSKRNVLGKGRFGILYKGRL------------------------ 294 Query 633 RGQELRVVLKVLDPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 + V +K L+ L F ++S H +L + G C+ E ++V Y+ Sbjct 295 -ADDTLVAVKRLNEERTKGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMA 353 Query 692 HGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARL 745 +G + LR R G+ + W + +A A L+YL ++ ++H +V NILL Sbjct 354 NGSVASCLRERPEGNPALDWPKRKHIALGSARGLAYLHDHCDQKIIHLDVKAANILLDEE 413 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800 A + D G+ + V I +APE L G + S D +G+ Sbjct 414 FEAV-------VGDFGLAKLMNYNDSHVTTAVRGTIGHIAPEYLSTGKS--SEKTDVFGY 464 Query 801 GATLLEICFDGEAPLQSR--SPSEKEHFYQRQHRLPEPSCPQL--ATLTSQCLTYEPTQR 856 G LLE+ +A +R + + + L E L A L + + E Q Sbjct 465 GVMLLELITGQKAFDLARLANDDDIMLLDWVKEVLKEKKLESLVDAELEGKYVETEVEQL 524 Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 + + ++ +++V+ + ++ ++ I D + Sbjct 525 IQMALLCTQSSAMERPKMSEVVRMLEGDGLAERWEEWQKEEMPIHDFNYQAY 576 >sp|Q641K5|NUAK1_MOUSE NUAK family SNF1-like kinase 1 OS=Mus musculus OX=10090 GN=Nuak1 PE=1 SV=1 Length=658 Score = 221 bits (563), Expect = 1e-59, Method: Composition-based stats. Identities = 67/292 (23%), Positives = 113/292 (39%), Gaps = 31/292 (11%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG 937 K + LG+G +GKV T +G +VA+K+++ D Sbjct 37 PRKPHGVKRHHHKHNLKHRYELQETLGKGTYGKVK----RATERFSGRVVAIKSIRKDKI 92 Query 938 PQHRS--GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHS 994 ++EI+I+ +L H HII E++ + + ++MEY G L DY+ R Sbjct 93 KDELDMVHIRREIEIMSSLNHPHIISIYEVFENKDK--IVIIMEYASKGELYDYISERRR 150 Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + + F +QI + Y H +HRDL N+LLD++ +KI DFGL+ + Sbjct 151 LSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKD--- 207 Query 1055 YRVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 + + + +PE + + D W+ GV LY L+ Sbjct 208 -KFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLIYGTMPFD----------- 255 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L + GE R P + L++ R T E++ Sbjct 256 ----GFDHKNLIRQISSGEY--REPTQPSDARGLIRWMLMVNPDRRATIEDI 301 Score = 167 bits (422), Expect = 1e-41, Method: Composition-based stats. Identities = 51/321 (16%), Positives = 89/321 (28%), Gaps = 40/321 (12%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 LG+GT V R G V +K + Sbjct 57 ELQETLGKGTYGKVKRATERFSGR------------------------VVAIKSIRKDKI 92 Query 650 DIALA---FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 L +MS ++H H+ ++ V + +++ EY G L ++ ER + Sbjct 93 KDELDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYI-SERRRL 151 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 +Q+ SA+ Y +VH ++ NILL + IK++D G+ Sbjct 152 SERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLD-------DNCNIKIADFGLSNLY 204 Query 767 LSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + + +PE + G +D W G L + G P Sbjct 205 QKDKFLQTFCGSPLYASPEIVNGRPYR-GPEVDSWALGVLLYTLI-YGTMPFDGFDHKNL 262 Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 L L P +R + I + + Sbjct 263 IRQISSGEYREPTQPSDARGLIRWMLMVNPDRRATIEDIANHWWVNWGYKSSVCDCDALP 322 Query 884 SPASDPTVFHKRYLKKIRDLG 904 S + + L Sbjct 323 DSESPLLARIIDWHHRSTGLQ 343 >sp|P28178|PK2_DICDI Protein kinase 2 OS=Dictyostelium discoideum OX=44689 GN=pkgB PE=1 SV=2 Length=479 Score = 216 bits (551), Expect = 1e-59, Method: Composition-based stats. Identities = 66/260 (25%), Positives = 107/260 (41%), Gaps = 29/260 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960 +G+G FGKV + + A+K L+ D + + K E IL+ + H I+ Sbjct 159 IGKGSFGKVMQVKKKGEDK----IFAMKVLRKDAIIARKQVNHTKSEKTILQCISHPFIV 214 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHY 1019 Q + L +V+++V G L +L R ++ ++A +I + +LH Q Sbjct 215 NLHYAF--QTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIVSALDHLHKQDI 272 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 ++RDL N+LLD++ + I DFGL+K + + + APE L + Sbjct 273 VYRDLKPENILLDSEGHICITDFGLSKKIETTDGTFT----FCGTPEYLAPEVLNGHGHG 328 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 A D WS G LYE+LT S V + + + GE L P Sbjct 329 CAVDWWSLGTLLYEMLTGLPPFYSQ---------------NVSTMYQKILNGE-LKIPTY 372 Query 1140 CPCEVYHLMKNCWETEASFR 1159 E L++ E R Sbjct 373 ISPEAKSLLEGLLTREVDKR 392 Score = 169 bits (429), Expect = 1e-43, Method: Composition-based stats. Identities = 56/271 (21%), Positives = 108/271 (40%), Gaps = 36/271 (13%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + + L+ +G+G+ V + K ED + + ++ + K ++ Sbjct 150 KDDFELLNVIGKGSFGKV-------------MQVKKKGEDKIFAMKVLRKDAIIARKQVN 196 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + +++ +SH + +H + MV ++V G L L+RE G Sbjct 197 HTKS--------EKTILQCISHPFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLKRE-GR 247 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 + A ++ SAL +L +++V+ ++ NILL G I ++D G+ Sbjct 248 FSEPRVKIYAAEIVSALDHLHKQDIVYRDLKPENILLDSEG-------HICITDFGLSKK 300 Query 766 ALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS- 821 + + +LAPE L G + A+D W G L E+ G P S++ S Sbjct 301 IETTDGTFTFCGTPEYLAPEVLNG--HGHGCAVDWWSLGTLLYEML-TGLPPFYSQNVST 357 Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYE 852 + + ++P P+ +L LT E Sbjct 358 MYQKILNGELKIPTYISPEAKSLLEGLLTRE 388 >sp|Q5EG47|AAPK1_MOUSE 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Mus musculus OX=10090 GN=Prkaa1 PE=1 SV=2 Length=559 Score = 218 bits (556), Expect = 1e-59, Method: Composition-based stats. Identities = 76/274 (28%), Positives = 110/274 (40%), Gaps = 30/274 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRT 953 + LG G FGKV + ++ TG VAVK L ++EI L+ Sbjct 26 HYILGDTLGVGTFGKVKVG----KHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKL 81 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012 H HIIK + + +VMEYV G L DY+ ++ + + QQI G+ Sbjct 82 FRHPHIIKLYQVISTPSD--IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVD 139 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Y H +HRDL NVLLD KI DFGL+ + +G +R SP + APE Sbjct 140 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGE---FLRTSCGSPN-YAAPEV 195 Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + D+WS GV LY LL V L + + G Sbjct 196 ISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDH---------------VPTLFKKICDG 240 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P V L+K+ + + R +++ Sbjct 241 IFYT-PQYLNPSVISLLKHMLQVDPMKRAAIKDI 273 Score = 182 bits (463), Expect = 2e-47, Method: Composition-based stats. Identities = 54/298 (18%), Positives = 94/298 (32%), Gaps = 39/298 (13%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 Q RV LG GT V G+ + G Sbjct 15 KQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGH----------------------- 51 Query 637 LRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +V +K+L+ D+ + H H+ ++ V + MV EYV G Sbjct 52 -KVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGG 110 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L ++ + G + + QQ+ S + Y +VH ++ N+LL Sbjct 111 ELFDYICKN-GRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD-------AHM 162 Query 754 FIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ E + APE + G + +D W G L + Sbjct 163 NAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYA-GPEVDIWSSGVILYALLCG 221 Query 811 GEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 P+ + P+ P + +L L +P +R + + I Sbjct 222 TLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRAAIKDIREHEWF 279 >sp|Q75L42|CIPKH_ORYSJ CBL-interacting protein kinase 17 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK17 PE=2 SV=1 Length=454 Score = 216 bits (549), Expect = 1e-59, Method: Composition-based stats. Identities = 67/273 (25%), Positives = 112/273 (41%), Gaps = 27/273 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--SGWKQEIDILRTL 954 + R LGEG+FGKV + TG AVK L R ++EI L+ L Sbjct 13 YEMGRTLGEGNFGKVKY----ARHLATGGHFAVKILDRGRVVSLRAGDQIRREIATLKLL 68 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAY 1013 H H+++ + + + +V+E+V G L + + + + + QQ+ +G++Y Sbjct 69 RHPHVVRLHEVAASKTK--IYMVLEFVNGGELFERIAVKGKLSEKEGRRLFQQLIDGVSY 126 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 H + HRDL NVL+D +KI DFGL+ + SP + APE L Sbjct 127 CHDRGVYHRDLKPENVLVDQKGNIKISDFGLSALPQHLGNDGLLHTTCGSPN-YIAPEVL 185 Query 1074 KEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + + + SD+WS GV LY +L ++ L + + +G+ Sbjct 186 QNKGYDGSLSDIWSCGVILYVMLIGYLPFDD---------------RNIVVLYQKIFKGD 230 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P +L++ E R + Sbjct 231 T-QIPKWLSHSAQNLLRRILEPNPMKRIDMAGI 262 Score = 171 bits (433), Expect = 2e-44, Method: Composition-based stats. Identities = 51/300 (17%), Positives = 88/300 (29%), Gaps = 44/300 (15%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647 LG+G V R G +K+LD Sbjct 14 EMGRTLGEGNFGKVKYARHLATGGHF------------------------AVKILDRGRV 49 Query 648 -HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 + + + H H+ +H V + MV E+V G L + +G + Sbjct 50 VSLRAGDQIRREIATLKLLRHPHVVRLHEVAASKTKIYMVLEFVNGGELFERI-AVKGKL 108 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + QQL +SY ++ + H ++ N+L+ + G IK+SD G+ Sbjct 109 SEKEGRRLFQQLIDGVSYCHDRGVYHRDLKPENVLVDQKG-------NIKISDFGLSALP 161 Query 767 LS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 ++APE L + D W G L + G P R+ Sbjct 162 QHLGNDGLLHTTCGSPNYIAPEVLQNKGYD-GSLSDIWSCGVILYVMLI-GYLPFDDRNI 219 Query 821 SEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 + +P+ L + L P +R I + + Sbjct 220 VVLYQKIFKGDTQIPKWLSHSAQNLLRRILEPNPMKRIDMAGIKSHEWFQKDYIPVLPYD 279 >sp|Q9LSS0|LRK17_ARATH L-type lectin-domain containing receptor kinase I.7 OS=Arabidopsis thaliana OX=3702 GN=LECRK17 PE=2 SV=1 Length=668 Score = 221 bits (563), Expect = 1e-59, Method: Composition-based stats. Identities = 78/281 (28%), Positives = 117/281 (42%), Gaps = 16/281 (6%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 + LG G FG+V + + VAVK + D G + EI +R+L H Sbjct 341 FNRSEFLGRGGFGEVYKGTLPRSREL--REVAVKRVSHD-GEHGMKQFVAEIVSMRSLKH 397 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAY 1013 ++ G C + E L LV EY+P GSL YL H S+ + L + I ++Y Sbjct 398 RSLVPLLGYCRRKHE--LLLVSEYMPNGSLDHYLFNHDRLSLPWWRRLAILRDIASALSY 455 Query 1014 LHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 LH + IHRD+ A NV+LD + ++GDFG+++ G + V + AP Sbjct 456 LHTEADQVVIHRDIKAANVMLDAEFNGRLGDFGMSRLYDRGADPSTT--AAVGTVGYMAP 513 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E L +DV++FGV L E +T P + I R + + R Sbjct 514 E-LTTMGASTGTDVYAFGVFLLE-VTCGRRPVEPGLPEAKRFLIKWVSECWKRSSLIDAR 571 Query 1131 GERL-PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 RL + +V L C RP E ++ L Sbjct 572 DPRLTEFSSQEVEKVLKLGLLCANLAPDSRPAMEQVVQYLN 612 Score = 210 bits (535), Expect = 5e-56, Method: Composition-based stats. Identities = 72/308 (23%), Positives = 118/308 (38%), Gaps = 61/308 (20%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELR-VVLKV 643 K + LG+G VY+G L R +ELR V +K Sbjct 337 ATKGFNRSEFLGRGGFGEVYKGTL-----------------------PRSRELREVAVKR 373 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE- 702 + F M + H L + G C R E ++V+EY+ +G LD +L Sbjct 374 VSHDGEHGMKQFVAEIVSMRSLKHRSLVPLLGYCRRKHELLLVSEYMPNGSLDHYLFNHD 433 Query 703 RGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 R +P ++ + + +ASALSYL ++ ++H ++ N++L +L D Sbjct 434 RLSLPWWRRLAILRDIASALSYLHTEADQVVIHRDIKAANVMLD-------AEFNGRLGD 486 Query 760 PGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ S V + ++APE GA ST D + FG LLE+ G P Sbjct 487 FGMSRLYDRGADPSTTAAVGTVGYMAPELTTMGA---STGTDVYAFGVFLLEV-TCGRRP 542 Query 815 LQSRSPSEKEHF------YQRQHRLPEPSCPQLATLTSQ-----------CLTYEPTQRP 857 ++ P K ++ L + P+L +SQ C P RP Sbjct 543 VEPGLPEAKRFLIKWVSECWKRSSLIDARDPRLTEFSSQEVEKVLKLGLLCANLAPDSRP 602 Query 858 SFRTILRD 865 + +++ Sbjct 603 AMEQVVQY 610 >sp|Q99ML2|TNK1_MOUSE Non-receptor tyrosine-protein kinase TNK1 OS=Mus musculus OX=10090 GN=Tnk1 PE=1 SV=2 Length=666 Score = 221 bits (563), Expect = 1e-59, Method: Composition-based stats. Identities = 93/276 (34%), Positives = 133/276 (48%), Gaps = 24/276 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRS--GWKQEIDILRTLYHEHI 959 LG G FG V + G VAVK+L+ GP + +E+ ++ L H H+ Sbjct 122 LGSGCFGVVHRGLWT-LPSGQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHV 180 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG----LAQLLLFAQQICEGMAYLH 1015 ++ G Q LQ+VME PLGSL L + +A L LF +Q+ MAYL Sbjct 181 LRLHGLVLGQ---PLQMVMELAPLGSLHARLTAPAPTPPLPVALLCLFLRQLAGAMAYLG 237 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + +HRDLA RN+LL + R++K+ DFGL + + Y + P W APE L++ Sbjct 238 SCGLVHRDLATRNLLLASPRMIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRQ 297 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 F ASDVW FGVTL+E+ + + + G L L L + RLP Sbjct 298 GAFSSASDVWMFGVTLWEMFSGGEEPWA-------------GVPPYLILQRLEKDRARLP 344 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 +P C +Y L CW + RP+F NL +L+ Sbjct 345 KPPLCSRALYSLALRCWAPHPADRPSFSNLEGLLQE 380 Score = 187 bits (476), Expect = 2e-48, Method: Composition-based stats. Identities = 74/295 (25%), Positives = 112/295 (38%), Gaps = 47/295 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + + + + LG G V+ G GQ + V +K Sbjct 111 IPEGAVRRGELLGSGCFGVVHRGLW---------------------TLPSGQSIPVAVKS 149 Query 644 LDPSHHDIAL----AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD--V 697 L F S+M ++ H H+ +HG+ + G MV E G L + Sbjct 150 LRVGPEGPMGTELGDFLREVSVMMKLEHPHVLRLHGLVL-GQPLQMVMELAPLGSLHARL 208 Query 698 WLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 +P+A + +QLA A++YL + LVH ++ RN+LLA + IK+ Sbjct 209 TAPAPTPPLPVALLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLA-------SPRMIKV 261 Query 758 SDPGV------GLGAL-SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +D G+ G R W APE L GA S+A D W FG TL E+ Sbjct 262 ADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRQGA--FSSASDVWMFGVTLWEMFSG 319 Query 811 GEAPLQSRSP---SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 GE P P ++ + + P L +L +C P RPSF + Sbjct 320 GEEPWAGVPPYLILQRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSFSNL 374 >sp|Q6XKY3|HOG1_HYPAT Mitogen-activated protein kinase hog1 OS=Hypocrea atroviridis OX=63577 GN=hog1 PE=3 SV=1 Length=357 Score = 212 bits (540), Expect = 1e-59, Method: Composition-based stats. Identities = 66/283 (23%), Positives = 107/283 (38%), Gaps = 29/283 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VAVK L K P +E+ + + L HE++ Sbjct 24 QPVGMGAFGLVC----SARDQLTNQNVAVKKLMKPFSTPVLAKRTYRELKLFKHLRHENV 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTAY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L + ER P + L++ + R T + Sbjct 252 SLPKRERQPLRNKFKNADDSAIDLLERMLVFDPKKRITATEAL 294 Score = 128 bits (321), Expect = 1e-30, Method: Composition-based stats. Identities = 38/231 (16%), Positives = 73/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHD-IALAFYE 657 +E D + M + RD+ V +K L P +A Y Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAVKKLMKPFSTPVLAKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L + H ++ + + + + VTE + L L + + Sbjct 67 ELKLFKHLRHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTAYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q54WX4|AURK_DICDI Aurora kinase OS=Dictyostelium discoideum OX=44689 GN=aurK PE=1 SV=1 Length=384 Score = 213 bits (543), Expect = 1e-59, Method: Composition-based stats. Identities = 62/279 (22%), Positives = 109/279 (39%), Gaps = 30/279 (11%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEID 949 + + LG G FG V L + +VA+K L + H ++EI+ Sbjct 105 WCIDDFDIGKLLGMGRFGHVYL----AREKKSQFIVALKVLFKNQLQTHNIEHQLRREIE 160 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQIC 1008 I L H +I++ G D +K + L++E+ G L + S + QI Sbjct 161 IQSHLRHPNILRLFGYFYD--DKRVFLIIEFAKGGECFKELQKVGSFNEQTAATYTLQIA 218 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 + + Y H++H IHRD+ N+L+ +KI DFG + P R + + Sbjct 219 DALRYCHSKHVIHRDIKPENLLIGVGGEIKIADFGWSVHAPN-----TKRSTFCGTLEYL 273 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE +++ + +DVWS G+ ++E L S K + I + + Sbjct 274 PPEVIEKKGYDQTADVWSLGILIFEFLVGRSPFTSDEEKNI-FHNIQENDVY-------- 324 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P E L+ ++ R T +++I Sbjct 325 -------YPSSISPEAKDLISRLLVSDPHQRITLKDVIN 356 Score = 185 bits (469), Expect = 8e-50, Method: Composition-based stats. Identities = 56/312 (18%), Positives = 103/312 (33%), Gaps = 41/312 (13%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + LG G +VY R++ + V LKVL Sbjct 108 DDFDIGKLLGMGRFGHVYLA------------------------REKKSQFIVALKVLFK 143 Query 647 SH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + H+I + S + H ++ + G ++ E+ + G L++ Sbjct 144 NQLQTHNIEHQLRREIEIQSHLRHPNILRLFGYFYDDKRVFLIIEFAKGGECFKELQKV- 202 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 G Q+A AL Y +K+++H ++ N+L+ G IK++D G Sbjct 203 GSFNEQTAATYTLQIADALRYCHSKHVIHRDIKPENLLI-------GVGGEIKIADFGWS 255 Query 764 LGA--LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + A R + +L PE + D W G + E G +P S Sbjct 256 VHAPNTKRSTFCGTLEYLPPEVIE--KKGYDQTADVWSLGILIFEFLV-GRSPFTSDEEK 312 Query 822 EKEH-FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880 H + P P+ L S+ L +P QR + + ++ + + + Sbjct 313 NIFHNIQENDVYYPSSISPEAKDLISRLLVSDPHQRITLKDVINHPWIKKHAHPKSLEPT 372 Query 881 NPDSPASDPTVF 892 P + Sbjct 373 KLGLPLPSQMTY 384 >sp|Q0D0P5|HOG1_ASPTN Mitogen-activated protein kinase hog1 OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=hog1 PE=3 SV=2 Length=364 Score = 213 bits (541), Expect = 1e-59, Method: Composition-based stats. Identities = 66/283 (23%), Positives = 109/283 (39%), Gaps = 29/283 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + TG+ VAVK + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SAKDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 D+WS E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAACIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIRGICSENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L + ER P + + L++ ++ R + Sbjct 252 SLPKRERQPLANKFKNADPDAIDLLERMLVFDSKKRIRAGEAL 294 Score = 131 bits (329), Expect = 1e-31, Method: Composition-based stats. Identities = 34/231 (15%), Positives = 73/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + +D+ V +K ++ P ++ Y Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSAKDQLTGQPVAVKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAACIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q9NGW9|MKCB_DICDI Probable serine/threonine-protein kinase mkcB OS=Dictyostelium discoideum OX=44689 GN=mkcB PE=2 SV=1 Length=714 Score = 222 bits (566), Expect = 1e-59, Method: Composition-based stats. Identities = 61/272 (22%), Positives = 109/272 (40%), Gaps = 25/272 (9%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 K +G+G FG V + +VA+K + Q + + +E IL Sbjct 437 MYKDSDQVGKGGFGTVYF----AKSTKEKRLVAIKKMPHVTKRQQQQNF-REAAILAKCD 491 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH 1015 H +I+K C D+ + +L +VME++ G+ + L A+++ +G+ YLH Sbjct 492 HPNIVKLHTCHIDK-DSNLWIVMEFMEGGTFEEAAKAWKFNENNLAYVAKELLKGLQYLH 550 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 H +HRDL + N+++ + VK+ DFGL + V + V FW APE +++ Sbjct 551 ENHMVHRDLKSANIMMSVEGKVKLIDFGLCEDVATSTPMHMV-----GSPFWMAPEMIQQ 605 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 D+WSF ++L E+ K + + + Sbjct 606 KYHSTPVDIWSFAISLLEMANQRPPMMESAVKAMFTVAT--------------DGATGFD 651 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P + C + + + R T E L+ Sbjct 652 DPALWSDCFKDFLSLCLKQDPAERATAEELLK 683 Score = 179 bits (455), Expect = 2e-45, Method: Composition-based stats. Identities = 49/281 (17%), Positives = 97/281 (35%), Gaps = 42/281 (15%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 +G+G VY + ++ V +K + Sbjct 442 DQVGKGGFGTVY------------------------FAKSTKEKRLVAIKKMPHVTKRQQ 477 Query 653 LAFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711 + A+++++ H ++ +H + +V E++E G + + Sbjct 478 QQNFREAAILAKCDHPNIVKLHTCHIDKDSNLWIVMEFMEGGTFEE--AAKAWKFNENNL 535 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE- 770 VA++L L YL ++VH ++ NI+++ G +KL D G+ + Sbjct 536 AYVAKELLKGLQYLHENHMVHRDLKSANIMMSVEG-------KVKLIDFGLCEDVATSTP 588 Query 771 -ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 V W+APE + + ST +D W F +LLE+ + P+ + Sbjct 589 MHMVGSPFWMAPEMIQQKYH--STPVDIWSFAISLLEMA-NQRPPMMESAVKAMFTVATD 645 Query 830 QHRL---PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 P S CL +P +R + +L+ Sbjct 646 GATGFDDPALWSDCFKDFLSLCLKQDPAERATAEELLKHPF 686 >sp|Q39192|SRK2D_ARATH Serine/threonine-protein kinase SRK2D OS=Arabidopsis thaliana OX=3702 GN=SRK2D PE=1 SV=1 Length=362 Score = 212 bits (540), Expect = 1e-59, Method: Composition-based stats. Identities = 77/295 (26%), Positives = 124/295 (42%), Gaps = 26/295 (9%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 D T +P P P + ++D+G G+FG L T+ T E+VAVK + Sbjct 1 MDPATNSPIMPIDLPIMHDSDRYDFVKDIGSGNFGVARLM----TDRVTKELVAVKYI-- 54 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-H 993 + G + ++EI R+L H +I+++K L +VMEY G L + + Sbjct 55 ERGEKIDENVQREIINHRSLRHPNIVRFKEVILTPSH--LAIVMEYAAGGELYERICNAG 112 Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEG 1051 + F QQ+ G++Y HA HRDL N LLD +KI DFG +K Sbjct 113 RFSEDEARFFFQQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSK---SS 169 Query 1052 HEYYRVREDGDSPVFWYAPECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 + + + +P + APE L ++ +DVWS GVTLY +L + P Sbjct 170 VLHSQPKSTVGTPA-YIAPEILLRQEYDGKLADVWSCGVTLYVMLVGAYPFEDPQ----- 223 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + + +L +P E HL+ + + + R T + Sbjct 224 -----EPRDYRKTIQRILSVTYSIPEDLHLSPECRHLISRIFVADPATRITIPEI 273 Score = 157 bits (398), Expect = 1e-40, Method: Composition-based stats. Identities = 55/329 (17%), Positives = 95/329 (29%), Gaps = 41/329 (12%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 D + +G G DR + V +K + Sbjct 19 DSDRYDFVKDIGSGNFG------------------------VARLMTDRVTKELVAVKYI 54 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + I + H ++ V + +V EY G L + G Sbjct 55 ERG-EKIDENVQREIINHRSLRHPNIVRFKEVILTPSHLAIVMEYAAGGELYERI-CNAG 112 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 QQL S +SY + H ++ N LL +P +K+ D G Sbjct 113 RFSEDEARFFFQQLISGVSYCHAMQICHRDLKLENTLLD-----GSPAPRLKICDFGYSK 167 Query 765 GAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 ++ + V ++APE L D W G TL + + P Sbjct 168 SSVLHSQPKSTVGTPAYIAPEILLRQEYD-GKLADVWSCGVTLYVMLVGAYPFEDPQEPR 226 Query 822 EKEHFYQRQ----HRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + QR + +PE P+ L S+ +P R + I D L+ Sbjct 227 DYRKTIQRILSVTYSIPEDLHLSPECRHLISRIFVADPATRITIPEITSDKWFLKNLPGD 286 Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 + S +P + ++ + Sbjct 287 LMDENRMGSQFQEPEQPMQSLDTIMQIIS 315 >sp|Q1ZXD6|ROCO5_DICDI Probable serine/threonine-protein kinase roco5 OS=Dictyostelium discoideum OX=44689 GN=roco5 PE=3 SV=1 Length=2800 Score = 229 bits (584), Expect = 1e-59, Method: Composition-based stats. Identities = 75/284 (26%), Positives = 123/284 (43%), Gaps = 39/284 (14%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-----SGWKQEIDILRTLYH 956 +GEG FG V G++VA+K + D G +++E+ + TL H Sbjct 2180 KVGEGGFGIVYKGKLR------GQLVAIKQITIDSGQAEAASEIYREFRREVWLSNTLTH 2233 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYL 1014 I+ KG C D +VMEY+P G+L +L + SI L A I + + ++ Sbjct 2234 PSIVSLKGYCLD----PCCIVMEYIPNGTLYSHLRKSFSSITWQLKLKIAINIADAIKHM 2289 Query 1015 H--AQHYIHRDLAARNVLLDNDRL----VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 H HRDL + N+L+ +D K+ DFG +AV + D S W Sbjct 2290 HGFTPKICHRDLKSPNILMLSDMNAAVVCKVSDFGETRAVVTSA----LGRDKLSNPIWL 2345 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 +PE ++ ++ +DV+SFG+ L+E+LT P + +L + + Sbjct 2346 SPEIMRGDEYTEKADVYSFGIVLWEILTGLLPFDEYPVAHSSF---------MYQLEDEI 2396 Query 1129 ERGERLPRPDKCP---CEVYHLMKNCWETEASFRPTFENLIPIL 1169 G R P + L+ +CW+ + RPTF ++ L Sbjct 2397 TNGLRPTIPQNSVCGHPDFITLITDCWQNDPLKRPTFIDIHSRL 2440 Score = 200 bits (509), Expect = 1e-50, Method: Composition-based stats. Identities = 64/338 (19%), Positives = 120/338 (36%), Gaps = 56/338 (17%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 + T I+R P + ++ K++ + +G+G VY+G+LR + Sbjct 2140 RSSITGEETIVRLDSLVPELMMSDIGPNFTLEYKDLEIIEKVGEGGFGIVYKGKLRGQ-- 2197 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA------LAFYETASLMSQVSH 667 V +K + F L + ++H Sbjct 2198 ------------------------LVAIKQITIDSGQAEAASEIYREFRREVWLSNTLTH 2233 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE- 726 + + G C+ +V EY+ +G L LR+ + K+ +A +A A+ ++ Sbjct 2234 PSIVSLKGYCLD--PCCIVMEYIPNGTLYSHLRKSFSSITWQLKLKIAINIADAIKHMHG 2291 Query 727 -NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPE 782 + H ++ NIL + + K+SD G ++ +++ WL+PE Sbjct 2292 FTPKICHRDLKSPNIL---MLSDMNAAVVCKVSDFGETRAVVTSALGRDKLSNPIWLSPE 2348 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS--------RSPSEKEHFYQRQHRLP 834 + G + + D + FG L EI G P E E + +P Sbjct 2349 IMRG--DEYTEKADVYSFGIVLWEIL-TGLLPFDEYPVAHSSFMYQLEDEITNGLRPTIP 2405 Query 835 E---PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 + P TL + C +P +RP+F I L + Sbjct 2406 QNSVCGHPDFITLITDCWQNDPLKRPTFIDIHSRLLIM 2443 >sp|Q9Z265|CHK2_MOUSE Serine/threonine-protein kinase Chk2 OS=Mus musculus OX=10090 GN=Chek2 PE=1 SV=1 Length=546 Score = 218 bits (555), Expect = 1e-59, Method: Composition-based stats. Identities = 98/436 (22%), Positives = 152/436 (35%), Gaps = 58/436 (13%) Query 774 ERIPWLAPECLPGGANSLSTAMDKWGFG-ATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832 PW L G ++L D + FG E CFDG ++ + R R Sbjct 93 GPAPWARLWALQDGFSNLDCVNDNYWFGRDKSCEYCFDGPLLRRTDKYRTYSKKHFRIFR 152 Query 833 -LPEPSCPQLA--------TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 + +C + T + L + + P L+ + D Sbjct 153 EMGPKNCYIVYIEDHSGNGTFVNTELIGKGKRCPLSNNSEIALSLCRNKVFVFFDLTVDD 212 Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 + + LG G G+V + T + VA+K + S Sbjct 213 QSVYP--KELRDEYIMSKTLGSGACGEVKMAF----ERKTCQKVAIKIISKRRFALGSSR 266 Query 944 -------WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSI 995 + EI+IL+ L H IIK K + +V+E + G L D + + Sbjct 267 EADTAPSVETEIEILKKLNHPCIIKIKDVF---DAEDYYIVLELMEGGELFDRVVGNKRL 323 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGH 1052 A L+ Q+ + YLH IHRDL NVLL D L+KI DFG +K + E Sbjct 324 KEATCKLYFYQMLVAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGE-- 381 Query 1053 EYYRVREDGDSPVFWYAPECLKEY---KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL 1109 +R +P + APE L + A D WS GV L+ L+ Sbjct 382 -TSLMRTLCGTPT-YLAPEVLVSNGTAGYSRAVDCWSLGVILFICLSGYPPFSE------ 433 Query 1110 ELIGIAQGQMTVLRLTELLERGERLPRPD---KCPCEVYHLMKNCWETEASFRPTFENLI 1166 T + L + + G+ P+ E L+K + R T E + Sbjct 434 --------HKTQVSLKDQITSGKYNFIPEVWTDVSEEALDLVKKLLVVDPKARLTTEEAL 485 Query 1167 --PIL--KTVHEKYQG 1178 P L + + +K+Q Sbjct 486 NHPWLQDEYMKKKFQD 501 Score = 153 bits (386), Expect = 1e-37, Method: Composition-based stats. Identities = 64/393 (16%), Positives = 117/393 (30%), Gaps = 59/393 (15%) Query 494 PDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLP 553 D ++ + F I F G + G + + C Sbjct 137 TDKYRTYSKKHFRI------FREMGPKNCYIV---YIEDHSGNGTFVNTELIGKGKRCPL 187 Query 554 QPGETSNLIIMRGARASPRTLNLSQLS-FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 L + R L + S + + + E LG G V Sbjct 188 SNNSEIALSLCRNKVFVFFDLTVDDQSVYPKELRDEYIMSKTLGSGACGEV--------- 238 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--------HHDIALAFYETASLMSQ 664 +R +V +K++ D A + ++ + Sbjct 239 ---------------KMAFERKTCQKVAIKIISKRRFALGSSREADTAPSVETEIEILKK 283 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 ++H + + V + +V E +E G L + + + A + Q+ A+ Y Sbjct 284 LNHPCIIKIKDV-FDAEDYYIVLELMEGGELFDRVVGNK-RLKEATCKLYFYQMLVAVQY 341 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAP 781 L ++H ++ N+LL+ + IK++D G +LAP Sbjct 342 LHENGIIHRDLKPENVLLSS----QEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAP 397 Query 782 ECL-PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS---EKEHFYQRQHRLPEPS 837 E L G S A+D W G L IC G P + + + + +PE Sbjct 398 EVLVSNGTAGYSRAVDCWSLGVIL-FICLSGYPPFSEHKTQVSLKDQITSGKYNFIPEVW 456 Query 838 ---CPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + L + L +P R + L Sbjct 457 TDVSEEALDLVKKLLVVDPKARLTTEEALNHPW 489 >sp|Q2H332|HOG1_CHAGB Mitogen-activated protein kinase HOG1 OS=Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) OX=306901 GN=HOG1 PE=3 SV=1 Length=360 Score = 212 bits (540), Expect = 1e-59, Method: Composition-based stats. Identities = 65/283 (23%), Positives = 107/283 (38%), Gaps = 29/283 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VA+K + K P +E+ +L+ L HE++ Sbjct 24 QPVGMGAFGLVC----SAKDQLTSQNVAIKKIMKPFSTPVLAKRTYRELKLLKHLKHENV 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTV-------LRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L ER P + L++ + R T + Sbjct 252 SLPMRERQPLKNKFKNADPTAIDLLERMLVFDPKKRITATEAL 294 Score = 128 bits (322), Expect = 9e-31, Method: Composition-based stats. Identities = 36/231 (16%), Positives = 75/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E D + M + +D+ V +K ++ P +A Y Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSAKDQLTSQNVAIKKIMKPFSTPVLAKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLKHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q9VI13|PAK_DROME Serine/threonine-protein kinase Pak OS=Drosophila melanogaster OX=7227 GN=Pak PE=1 SV=1 Length=704 Score = 222 bits (565), Expect = 1e-59, Method: Composition-based stats. Identities = 68/275 (25%), Positives = 112/275 (41%), Gaps = 23/275 (8%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 R K+ +G+G G V Y TG VA+K + P+ + EI ++R Sbjct 426 PNRKYTKMEKIGQGASGTV----YTAIESSTGMEVAIKQMNLSQQPK-KELIINEILVMR 480 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 H +++ Y E L +VMEY+P GSL D + + Q+ +++ + + Sbjct 481 ENKHPNVVNYLDSYLVSEE--LWVVMEYLPGGSLTDVVTETCMDEGQIAAVCREVLQALE 538 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 +LHA IHRD+ + N+LL D VK+ DFG + R +W APE Sbjct 539 FLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISP---EQSKRTTMVGTPYWMAPEV 595 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + ++ D+WS G+ E++ PP + T + E+ E+ Sbjct 596 VTRKQYGPKVDLWSLGIMAIEMV-----EGEPPYLNENPLKALYLIATNGK-PEIKEK-- 647 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 DK + C E E R + +L+ Sbjct 648 -----DKLSSAFQDFLDQCLEVEVDRRASALDLLK 677 Score = 183 bits (464), Expect = 1e-46, Method: Composition-based stats. Identities = 49/276 (18%), Positives = 90/276 (33%), Gaps = 44/276 (16%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 ++ T++ +GQG VY + + V +K + Sbjct 426 PNRKYTKMEKIGQGASGTVY------------------------TAIESSTGMEVAIKQM 461 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + S +M + H ++ + E +V EY+ G L + Sbjct 462 NLSQQPKKELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVV--TET 519 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV-- 762 + V +++ AL +L ++H ++ NILL G +KL+D G Sbjct 520 CMDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILL-------GLDGSVKLTDFGFCA 572 Query 763 --GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 R V W+APE + +D W G +E+ +GE P + +P Sbjct 573 QISPEQSKRTTMVGTPYWMAPEVVT--RKQYGPKVDLWSLGIMAIEMV-EGEPPYLNENP 629 Query 821 SEKEHFYQRQHRLP----EPSCPQLATLTSQCLTYE 852 + + + + QCL E Sbjct 630 LKALYLIATNGKPEIKEKDKLSSAFQDFLDQCLEVE 665 >sp|Q9STF0|LRKS3_ARATH Receptor like protein kinase S.3 OS=Arabidopsis thaliana OX=3702 GN=LECRKS3 PE=3 SV=1 Length=337 Score = 211 bits (538), Expect = 1e-59, Method: Composition-based stats. Identities = 66/266 (25%), Positives = 106/266 (40%), Gaps = 20/266 (8%) Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCED 968 G V + +AVK + D Q +I + L H+++++ G C Sbjct 62 GTVYKG-----KLSSNAQIAVKRVSLDA-EQDTKHLVSQIVGIGKLRHKNLVQLLGYCRR 115 Query 969 QGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 +GE L LV +Y+P G+L D+L R ++ +Q + + + YLH Q +HRD+ Sbjct 116 KGE--LLLVYDYMPYGNLDDFLFNEERPNLSWSQRFHIIKGVASALLYLHEQIVLHRDVK 173 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 A NVLLD D ++ D+GLA+ + R V + APE + +DV+ Sbjct 174 AANVLLDEDLNGRL-DYGLAR-------FGTNRNPMLGSVGYVAPELIITGMPTTKADVY 225 Query 1086 SFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144 SFG L E + P + LI L + K V Sbjct 226 SFGALLLEFACGRMFIEYPGKPEEFNLISWVCQCWKRGNLVGARDARLEGDYVCKEIEMV 285 Query 1145 YHLMKNCWETEASFRPTFENLIPILK 1170 L C + RP+ ++ L+ Sbjct 286 LKLGLLCAQYNPEDRPSMSQVVNYLE 311 Score = 196 bits (498), Expect = 3e-54, Method: Composition-based stats. Identities = 59/299 (20%), Positives = 101/299 (34%), Gaps = 53/299 (18%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 K + G VY+G+L ++ +K + Sbjct 46 ATKGFKESELFGTEANGTVYKGKLSSNA-------------------------QIAVKRV 80 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-ER 703 + ++ H +L + G C R E ++V +Y+ +G LD +L ER Sbjct 81 SLDAEQDTKHLVSQIVGIGKLRHKNLVQLLGYCRRKGELLLVYDYMPYGNLDDFLFNEER 140 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 ++ + + + + +ASAL YL + ++H +V N+LL D G+ Sbjct 141 PNLSWSQRFHIIKGVASALLYLHEQIVLHRDVKAANVLLDEDLNGRL--------DYGLA 192 Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 +R + + ++APE + G +T D + FGA LLE P E Sbjct 193 RFGTNRNPMLGSVGYVAPELIITGMP--TTKADVYSFGALLLEFACGRMFIEYPGKPEEF 250 Query 824 EHFYQ-------------RQHRLP----EPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 R RL + L C Y P RPS ++ Sbjct 251 NLISWVCQCWKRGNLVGARDARLEGDYVCKEIEMVLKLGLLCAQYNPEDRPSMSQVVNY 309 >sp|P28829|BYR2_SCHPO Protein kinase byr2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=byr2 PE=1 SV=1 Length=659 Score = 221 bits (562), Expect = 1e-59, Method: Composition-based stats. Identities = 70/282 (25%), Positives = 118/282 (42%), Gaps = 32/282 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG-------WKQEID 949 + +G G FG+V L N +GE++AVK + D + + EI Sbjct 394 WIRGALIGSGSFGQVYLGM----NASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIA 449 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQIC 1008 +L+ L HEHI++Y G + L + +EYVP GS+ L + L+ F +Q Sbjct 450 LLQELSHEHIVQYLGS--NLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTL 507 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV---REDGDSPV 1065 +G+ YLH++ +HRD+ N+L+DN +KI DFG++K + + R Sbjct 508 KGLEYLHSRGIVHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQGSS 567 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 FW APE +K+ +D+WS G + E+LT ++ Sbjct 568 FWMAPEVVKQTMHTEKTDIWSLGCLVIEMLTSKHP---------------YPNCDQMQAI 612 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + P ++ + + + RPT L+ Sbjct 613 FRIGENILPEFPSNISSSAIDFLEKTFAIDCNLRPTASELLS 654 Score = 171 bits (434), Expect = 4e-43, Method: Composition-based stats. Identities = 57/290 (20%), Positives = 98/290 (34%), Gaps = 42/290 (14%) Query 563 IMRGARASPRTLNLSQLSFHRVDQKE--ITQLS--HLGQGTRTNVYEGRLRVEGSGDPEE 618 I + + SP + + D + I + +G G+ VY G G + Sbjct 364 IEQPSPISPTSTTSEDTNTLEEDTDDQSIKWIRGALIGSGSFGQVYLGMNASSGELMAVK 423 Query 619 GKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCV 678 + D R K+LD A +L+ ++SH H+ G + Sbjct 424 QVILDSVSESKDRHA--------KLLD--------ALAGEIALLQELSHEHIVQYLGSNL 467 Query 679 RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGR 738 + EYV G + L G +Q L YL ++ +VH ++ G Sbjct 468 NSDHLNIFLEYVPGGSVAGLL-TMYGSFEETLVKNFIKQTLKGLEYLHSRGIVHRDIKGA 526 Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER----------IPWLAPECLPGGA 788 NIL+ G IK+SD G+ + W+APE + Sbjct 527 NILVDNKG-------KIKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPEVVKQTM 579 Query 789 NSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838 + + D W G ++E+ + P + + F ++ LPE Sbjct 580 H--TEKTDIWSLGCLVIEMLTS-KHPYPNCDQMQAI-FRIGENILPEFPS 625 >sp|Q8RWZ5|SD25_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase SD2-5 OS=Arabidopsis thaliana OX=3702 GN=SD25 PE=1 SV=1 Length=821 Score = 224 bits (570), Expect = 1e-59, Method: Composition-based stats. Identities = 71/314 (23%), Positives = 126/314 (40%), Gaps = 25/314 (8%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS 942 LG+G FG V G +AVK L + Q + Sbjct 479 MPIRFAYKDLQSATNNFSVKLGQGGFGSVYEGTL-----PDGSRLAVKKL--EGIGQGKK 531 Query 943 GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGL 997 ++ E+ I+ +++H H+++ +G C + + L E++ GSL ++ R + Sbjct 532 EFRAEVSIIGSIHHLHLVRLRGFCAEGAHR--LLAYEFLSKGSLERWIFRKKDGDVLLDW 589 Query 998 AQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 A +G+AYLH +H D+ N+LLD++ K+ DFGLAK + + Sbjct 590 DTRFNIALGTAKGLAYLHEDCDARIVHCDIKPENILLDDNFNAKVSDFGLAKLMTREQSH 649 Query 1055 YRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFL-ELIG 1113 V + APE + Y SDV+S+G+ L EL+ + T Sbjct 650 --VFTTMRGTRGYLAPEWITNYAISEKSDVYSYGMVLLELIGGRKNYDPSETSEKCHFPS 707 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170 A +M +L ++++ ++ D V MK C + + RP+ ++ +L+ Sbjct 708 FAFKKMEEGKLMDIVD--GKMKNVDVTDERVQRAMKTALWCIQEDMQTRPSMSKVVQMLE 765 Query 1171 TVHEKYQGQAPSVF 1184 V Q + S Sbjct 766 GVFPVVQPPSSSTM 779 Score = 196 bits (498), Expect = 2e-50, Method: Composition-based stats. Identities = 57/250 (23%), Positives = 91/250 (36%), Gaps = 47/250 (19%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LGQG +VYEG L R+ +K L Sbjct 498 KLGQGGFGSVYEGTLPDGS-------------------------RLAVKKL-EGIGQGKK 531 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH---VPMAW 710 F S++ + H HL + G C G ++ E++ G L+ W+ R++ + Sbjct 532 EFRAEVSIIGSIHHLHLVRLRGFCAEGAHRLLAYEFLSKGSLERWIFRKKDGDVLLDWDT 591 Query 711 KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 + +A A L+YL +VH ++ NILL + K+SD G+ Sbjct 592 RFNIALGTAKGLAYLHEDCDARIVHCDIKPENILLD-------DNFNAKVSDFGLAKLMT 644 Query 768 SREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + V +LAPE + ++S D + +G LLE+ G SE Sbjct 645 REQSHVFTTMRGTRGYLAPEWITN--YAISEKSDVYSYGMVLLELI-GGRKNYDPSETSE 701 Query 823 KEHFYQRQHR 832 K HF + Sbjct 702 KCHFPSFAFK 711 >sp|C0LGD6|Y1570_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g05700 OS=Arabidopsis thaliana OX=3702 GN=At1g05700 PE=1 SV=1 Length=852 Score = 224 bits (571), Expect = 2e-59, Method: Composition-based stats. Identities = 65/328 (20%), Positives = 128/328 (39%), Gaps = 17/328 (5%) Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919 R R + + + + K + LG+G FG V YD Sbjct 533 RIRNRRNKSVNSAPQTSPMAKSENKLLFTFADVIKMTNNFGQVLGKGGFGTVYHGFYD-- 590 Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979 VAVK L ++ Q ++ E+++L ++H ++ G + + + L+ E Sbjct 591 ----NLQVAVK-LLSETSAQGFKEFRSEVEVLVRVHHVNLTALIGYFHEGDQ--MGLIYE 643 Query 980 YVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDN 1033 ++ G++ D+L +H++ Q L A +G+ YLH +HRD+ N+LL+ Sbjct 644 FMANGNMADHLAGKYQHTLSWRQRLQIALDAAQGLEYLHCGCKPPIVHRDVKTSNILLNE 703 Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 K+ DFGL+++ + +P + P C + SD++SFGV L E Sbjct 704 KNRAKLADFGLSRSFHTESRSHVSTLVAGTP-GYLDPLCFETNGLNEKSDIYSFGVVLLE 762 Query 1094 LLTHCDSSQSPPTKFLELIGIA-QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCW 1152 ++T + TK + + + + +++ +V L + Sbjct 763 MITGKTVIKESQTKRVHVSDWVISILRSTNDVNNVIDSKMAKDFDVNSVWKVVELALSSV 822 Query 1153 ETEASFRPTFENLIPILKTVHEKYQGQA 1180 S RP +++ L ++ + Sbjct 823 SQNVSDRPNMPHIVRGLNECLQREESNK 850 Score = 194 bits (492), Expect = 2e-49, Method: Composition-based stats. Identities = 54/268 (20%), Positives = 92/268 (34%), Gaps = 47/268 (18%) Query 554 QPGETSNLIIMRGARASP--RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 + N + + SP ++ N +F V + LG+G VY G Sbjct 533 RIRNRRNKSVNSAPQTSPMAKSENKLLFTFADVIKMTNNFGQVLGKGGFGTVYHG----- 587 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 L+V +K+L + F ++ +V H +L Sbjct 588 ---------------------FYDNLQVAVKLLSETSAQGFKEFRSEVEVLVRVHHVNLT 626 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH-VPMAWKMVVAQQLASALSYLE---N 727 + G G + ++ E++ +G + L + H + ++ +A A L YL Sbjct 627 ALIGYFHEGDQMGLIYEFMANGNMADHLAGKYQHTLSWRQRLQIALDAAQGLEYLHCGCK 686 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER------VERIPWLAP 781 +VH +V NILL A KL+D G+ + +L P Sbjct 687 PPIVHRDVKTSNILLNEKNRA-------KLADFGLSRSFHTESRSHVSTLVAGTPGYLDP 739 Query 782 ECLPGGANSLSTAMDKWGFGATLLEICF 809 L N L+ D + FG LLE+ Sbjct 740 --LCFETNGLNEKSDIYSFGVVLLEMIT 765 >sp|U4PR86|MELK_CAEEL Maternal embryonic leucine zipper kinase OS=Caenorhabditis elegans OX=6239 GN=pig-1 PE=1 SV=1 Length=706 Score = 221 bits (564), Expect = 2e-59, Method: Composition-based stats. Identities = 65/283 (23%), Positives = 114/283 (40%), Gaps = 24/283 (8%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 + + +LG G FGKV L T+ T + VA+K + + Sbjct 1 MSKYEVLQGFYAVHDELGSGGFGKVRL----ATHLLTNQKVAIKIIDKKQLGHDLPRVQT 56 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQ 1005 E+D LR L H++I + E E +VMEY G + DY+ + + ++ F + Sbjct 57 EMDALRNLSHQNICRLYHYIE--TEDKFFIVMEYCSGGEMFDYIVRKERLEESEARHFFR 114 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 Q+ +A++H+Q Y HRDL N+LL D +K+ DFGL +G + Sbjct 115 QLVSAIAFVHSQGYAHRDLKPENLLLTEDLHLKLIDFGLCAKTEKGRIDKHNLDTCCGSP 174 Query 1066 FWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 + APE ++ ++ +DVWS G+ LY LL + +++ Sbjct 175 AYAAPELIQGLQYKGNEADVWSMGILLYTLLVGALPFED----------------DNMQI 218 Query 1125 TELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + P+ L++ + R + + L+ Sbjct 219 MYKKIQSGCFYEPEFLSPLSKQLLRAMLQVVPERRISVKKLLE 261 Score = 157 bits (397), Expect = 3e-38, Method: Composition-based stats. Identities = 48/320 (15%), Positives = 91/320 (28%), Gaps = 43/320 (13%) Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH--H 649 LG G V +V +K++D H Sbjct 14 HDELGSGGFGKV------------------------RLATHLLTNQKVAIKIIDKKQLGH 49 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 D+ + +SH ++ ++ + +V EY G + ++ R+ + + Sbjct 50 DLPR-VQTEMDALRNLSHQNICRLYHYIETEDKFFIVMEYCSGGEMFDYIVRKE-RLEES 107 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG------ 763 +QL SA++++ ++ H ++ N+LL +KL D G+ Sbjct 108 EARHFFRQLVSAIAFVHSQGYAHRDLKPENLLLTE-------DLHLKLIDFGLCAKTEKG 160 Query 764 -LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + + + + APE + G D W G L + Sbjct 161 RIDKHNLDTCCGSPAYAAPELIQGLQYK-GNEADVWSMGILLYTLLVGALPFEDDNMQIM 219 Query 823 KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 + PE P L L P +R S + +L + Sbjct 220 YKKIQSGCFYEPEFLSPLSKQLLRAMLQVVPERRISVKKLLEHDWLNHKYTQPVKWNTIY 279 Query 883 DSPASDPTVFHKRYLKKIRD 902 D D V + Sbjct 280 DKNFIDRDVARVMSKYYGFE 299 >sp|Q75H77|SAPKA_ORYSJ Serine/threonine-protein kinase SAPK10 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK10 PE=1 SV=1 Length=362 Score = 212 bits (540), Expect = 2e-59, Method: Composition-based stats. Identities = 73/286 (26%), Positives = 120/286 (42%), Gaps = 30/286 (10%) Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWK 945 P + + +RD+G G+FG L + G++VAVK + + G + + Sbjct 12 MDMPIMHDGDRYELVRDIGSGNFGVARLM----RSRADGQLVAVKYI--ERGDKIDENVQ 65 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFA 1004 +EI R+L H +II++K L +VMEY G L + + + F Sbjct 66 REIINHRSLRHPNIIRFKEVILTPTH--LAIVMEYASGGELFERICNAGRFSEDEARFFF 123 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDR--LVKIGDFGLAKAVPEGHEYYRVREDGD 1062 QQ+ G++Y H+ HRDL N LLD +KI DFG +K + + + Sbjct 124 QQLISGVSYCHSMQVCHRDLKLENTLLDGSTAPRLKICDFGYSK---SSVLHSQPKSTVG 180 Query 1063 SPVFWYAPECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 +P + APE L + ++ +DVWS GVTLY +L + P + T+ Sbjct 181 TPA-YIAPEVLLKKEYDGKIADVWSCGVTLYVMLVGAYPFEDPDEP-------KNFRKTI 232 Query 1122 LRLTELLERGERLPRPD--KCPCEVYHLMKNCWETEASFRPTFENL 1165 R+ G + PD E L+ + + R + + Sbjct 233 QRIL-----GVQYSIPDYVHISPECRDLIARIFVANPATRISIPEI 273 Score = 158 bits (400), Expect = 5e-41, Method: Composition-based stats. Identities = 54/329 (16%), Positives = 93/329 (28%), Gaps = 41/329 (12%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 D + +G G R R V +K + Sbjct 19 DGDRYELVRDIGSGNFG------------------------VARLMRSRADGQLVAVKYI 54 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + I + H ++ V + +V EY G L + G Sbjct 55 ERGDK-IDENVQREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERI-CNAG 112 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 QQL S +SY + + H ++ N LL T+P +K+ D G Sbjct 113 RFSEDEARFFFQQLISGVSYCHSMQVCHRDLKLENTLLD-----GSTAPRLKICDFGYSK 167 Query 765 GAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 ++ + V ++APE L D W G TL + P Sbjct 168 SSVLHSQPKSTVGTPAYIAPEVLLKKEYD-GKIADVWSCGVTLYVMLVGAYPFEDPDEPK 226 Query 822 E----KEHFYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + Q+ +P+ P+ L ++ P R S I L+ Sbjct 227 NFRKTIQRILGVQYSIPDYVHISPECRDLIARIFVANPATRISIPEIRNHPWFLKNLPAD 286 Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 + S +P + + ++ L Sbjct 287 LMDDSKMSSQYEEPEQPMQSMDEIMQILA 315 >sp|O70146|TESK1_MOUSE Dual specificity testis-specific protein kinase 1 OS=Mus musculus OX=10090 GN=Tesk1 PE=1 SV=3 Length=627 Score = 220 bits (560), Expect = 2e-59, Method: Composition-based stats. Identities = 73/290 (25%), Positives = 123/290 (42%), Gaps = 28/290 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +G G F +V Y + +G+++ LK + P +RS +E+ ++ L H Sbjct 52 FDCAEKIGAGFFSEV----YKVRHRQSGQVM---VLKMNKLPSNRSNTLREVQLMNRLRH 104 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLH 1015 +I+++ G C QG+ L + EY+ G+L L + L A I +G+ YLH Sbjct 105 PNILRFMGVCVHQGQ--LHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIAQGLRYLH 162 Query 1016 AQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVRE-DGDSPVFWYAPE 1071 A+ HRDL ++N L+ D +GDFGLA+ +P E R +W APE Sbjct 163 AKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGTRKEPLAVVGSPYWMAPE 222 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 L+ + +DV++FG+ L EL+ + + + T++ Sbjct 223 VLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVG-------- 274 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP 1181 + CP L +C E S R F + L+ + E+ P Sbjct 275 ------NDCPLPFLLLAIHCCSMEPSTRAPFTEITQHLEQILEQQPEATP 318 Score = 192 bits (489), Expect = 2e-50, Method: Composition-based stats. Identities = 69/316 (22%), Positives = 113/316 (36%), Gaps = 45/316 (14%) Query 569 ASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLV 628 +S R L + S RVD + +G G + VY+ R R G Sbjct 34 SSYRALRSAVSSLARVD--DFDCAEKIGAGFFSEVYKVRHRQSG---------------- 75 Query 629 PGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 +V++ ++ + + LM+++ H ++ GVCV + +TE Sbjct 76 ---------QVMVLKMNKLPSNRSNT-LREVQLMNRLRHPNILRFMGVCVHQGQLHALTE 125 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 Y+ G L+ L + ++ +A +A L YL K + H ++ +N L+ R Sbjct 126 YMNGGTLEQLLSSPE-PLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRR---- 180 Query 749 EGTSPFIKLSDPGVG-LGALSREER-------VERIPWLAPECLPGGANSLSTAMDKWGF 800 E + D G+ + RE V W+APE L G D + F Sbjct 181 EDRGFTAVVGDFGLAEKIPVYREGTRKEPLAVVGSPYWMAPEVLRGEL--YDEKADVFAF 238 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-LPEPSCP-QLATLTSQCLTYEPTQRPS 858 G L E+ A +E R L CP L C + EP+ R Sbjct 239 GIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSTRAP 298 Query 859 FRTILRDLTRLQPHNL 874 F I + L ++ Sbjct 299 FTEITQHLEQILEQQP 314 >sp|Q8CFH6|SIK2_MOUSE Serine/threonine-protein kinase SIK2 OS=Mus musculus OX=10090 GN=Sik2 PE=1 SV=1 Length=931 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 71/291 (24%), Positives = 112/291 (38%), Gaps = 29/291 (10%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADC 936 + + + LG+G+F V L + T VA+K + K+ Sbjct 1 MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLG----RHRTTKTEVAIKIIDKSQL 56 Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SI 995 + +E+ I++ L H HIIK E + L LV EY G + DYL H + Sbjct 57 DAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKS--MLYLVTEYAKNGEIFDYLANHGRL 114 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 ++ QI + Y H + +HRDL A N+LLDN+ +KI DFG G Sbjct 115 NESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLLDNNMNIKIADFGFGNFFKTGE--- 171 Query 1056 RVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + + APE + ++ D+WS GV LY L+ P Sbjct 172 -LLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGP---------- 220 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 T+ L + + G R P + HL++ + S R + + Sbjct 221 -----TLPILRQRVLEG-RFRIPYFMSEDCEHLIRRMLVLDPSKRLSIAQI 265 Score = 195 bits (496), Expect = 8e-50, Method: Composition-based stats. Identities = 74/383 (19%), Positives = 125/383 (33%), Gaps = 48/383 (13%) Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 PR L + RV +I LG+G V GR R Sbjct 7 PRHLQRGPV---RVGFYDIE--GTLGKGNFAVVKLGRHRT-------------------- 41 Query 631 RDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 + V +K++D S D Y +M + H H+ ++ V +VTE Sbjct 42 ----TKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTE 97 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 Y ++G + +L G + + Q+ SA+ Y + +VH ++ N+LL Sbjct 98 YAKNGEIFDYLANH-GRLNESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLLDN---- 152 Query 749 EGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + IK++D G G + E P+ APE G +D W G L Sbjct 153 ---NMNIKIADFGFGNFFKTGELLATWCGSPPYAAPEVFEGQQYE-GPQLDIWSMGVVLY 208 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + P ++ + + R+P L + L +P++R S I Sbjct 209 VLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLSIAQIKEH 268 Query 866 LTRLQPHNLADVLTVNPDSPASDPTVFHKRYL-KKIRDLGEGHFGKVSLYCYDPTNDGTG 924 L + + + + + + LG V N Sbjct 269 KWMLIEVPVQRPILYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKTVE----SLQNKSYN 324 Query 925 EMVAVKALKADCGPQHRSGWKQE 947 A+ L + HRS + E Sbjct 325 HFAAIYFLLVERLKSHRSSFPVE 347 >sp|C0LGJ1|Y1743_ARATH Probable LRR receptor-like serine/threonine-protein kinase At1g74360 OS=Arabidopsis thaliana OX=3702 GN=At1g74360 PE=1 SV=1 Length=1106 Score = 227 bits (578), Expect = 2e-59, Method: Composition-based stats. Identities = 64/284 (23%), Positives = 118/284 (42%), Gaps = 19/284 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY-----HE 957 +G G +G V G VAVK L+ + + ++ E+++L H Sbjct 820 VGRGGYGTVYRGVL-----PDGREVAVKKLQREGTEAEKE-FRAEMEVLSANAFGDWAHP 873 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHA 1016 ++++ G C D EK LV EY+ GSL + + + + + + A + G+ +LH Sbjct 874 NLVRLYGWCLDGSEK--ILVHEYMGGGSLEELITDKTKLQWKKRIDIATDVARGLVFLHH 931 Query 1017 QH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + +HRD+ A NVLLD ++ DFGLA+ + G + V + + APE Sbjct 932 ECYPSIVHRDVKASNVLLDKHGNARVTDFGLARLLNVGDSH--VSTVIAGTIGYVAPEYG 989 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + ++ DV+S+GV EL T + +E + + + G + Sbjct 990 QTWQATTRGDVYSYGVLTMELATGRRAVDGGEECLVEWARRVMTGNMTAKGSPITLSGTK 1049 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 + E+ + C RP + ++ +L + K + Sbjct 1050 PGNGAEQMTELLKIGVKCTADHPQARPNMKEVLAMLVKISGKAE 1093 Score = 187 bits (475), Expect = 5e-47, Method: Composition-based stats. Identities = 47/242 (19%), Positives = 91/242 (38%), Gaps = 48/242 (20%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 ++ +G+G VY G L V +K L Sbjct 810 ATSNFSEERVVGRGGYGTVYRGVLPDGR-------------------------EVAVKKL 844 Query 645 DPSHHDIALAFYETASLMS-----QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 + F ++S +H +L ++G C+ G E I+V EY+ G L+ + Sbjct 845 QREGTEAEKEFRAEMEVLSANAFGDWAHPNLVRLYGWCLDGSEKILVHEYMGGGSLEELI 904 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIK 756 ++ + ++ +A +A L +L ++ ++VH +V N+LL + G + Sbjct 905 -TDKTKLQWKKRIDIATDVARGLVFLHHECYPSIVHRDVKASNVLLDKHG-------NAR 956 Query 757 LSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 ++D G+ + V I ++APE G +T D + +G +E+ Sbjct 957 VTDFGLARLLNVGDSHVSTVIAGTIGYVAPEY--GQTWQATTRGDVYSYGVLTMELATGR 1014 Query 812 EA 813 A Sbjct 1015 RA 1016 >sp|Q86AD7|MYLKB_DICDI Probable myosin light chain kinase DDB_G0271550 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0271550 PE=3 SV=1 Length=392 Score = 213 bits (542), Expect = 2e-59, Method: Composition-based stats. Identities = 65/281 (23%), Positives = 105/281 (37%), Gaps = 32/281 (11%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRT 953 + + ++G G F V T+ TG+ VA+KA+ K + +EI+I++ Sbjct 18 DFYEFGPEIGRGAFSIVR----QGTHKDTGDQVAIKAISKQHVSEADMKRFTREIEIMKK 73 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012 L H++II+ + L LV+E + G L D + + + +QI + Sbjct 74 LKHKNIIQLIEVFDSND--YLYLVLELIRGGELFDKIVEKGNYSEKDACNLVRQIVSAVE 131 Query 1013 YLHAQHYIHRDLAARNVLLDNDRL----VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 Y+H HRDL N+L D V+I DFGL+K G E + + Sbjct 132 YMHQHGVCHRDLKPENLLCSGDDEKEEIVRIADFGLSKIFEGGEEL----KTACGTPDYV 187 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 APE L+ + + D+WS GV Y LL + L ++L Sbjct 188 APEILECKPYDTSVDMWSIGVITYILLCGFAPFYADTHHEL--------------FQKIL 233 Query 1129 ERGERLPRPD--KCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + P P+ + R T I Sbjct 234 DLEYDFPEPEWNGITDLAKDFISQLLIINPEERWTASQCIK 274 Score = 167 bits (422), Expect = 1e-43, Method: Composition-based stats. Identities = 53/304 (17%), Positives = 109/304 (36%), Gaps = 48/304 (16%) Query 581 FHRVDQKEITQLS-------HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 F R+ +K+ +++ +G+G + V +G + G Sbjct 5 FKRIGRKKDSKIEDFYEFGPEIGRGAFSIVRQGTHKDTGD-------------------- 44 Query 634 GQELRVVLKVLDPSHHDI--ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 +V +K + H F +M ++ H ++ + V +V E + Sbjct 45 ----QVAIKAISKQHVSEADMKRFTREIEIMKKLKHKNIIQLIEVFDSNDYLYLVLELIR 100 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G L + E+G+ + +Q+ SA+ Y+ + H ++ N+L + + Sbjct 101 GGELFDKI-VEKGNYSEKDACNLVRQIVSAVEYMHQHGVCHRDLKPENLLCS---GDDEK 156 Query 752 SPFIKLSDPGVGL---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 ++++D G+ G + ++APE L T++D W G I Sbjct 157 EEIVRIADFGLSKIFEGGEELKTACGTPDYVAPEILE--CKPYDTSVDMWSIGVITY-IL 213 Query 809 FDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQLATL----TSQCLTYEPTQRPSFRTIL 863 G AP + + E + ++ PEP + L SQ L P +R + + Sbjct 214 LCGFAPFYADTHHELFQKILDLEYDFPEPEWNGITDLAKDFISQLLIINPEERWTASQCI 273 Query 864 RDLT 867 + Sbjct 274 KHPW 277 >sp|F1QGZ6|MELK_DANRE Maternal embryonic leucine zipper kinase OS=Danio rerio OX=7955 GN=melk PE=2 SV=1 Length=676 Score = 221 bits (562), Expect = 2e-59, Method: Composition-based stats. Identities = 74/274 (27%), Positives = 121/274 (44%), Gaps = 26/274 (9%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 + + +G G F KV L + TGE VA+K ++ K EI+ ++ L Sbjct 12 HYEVYETIGSGGFAKVKLG----RHKLTGEKVAIKIMEKKDLGDDLPRVKIEIEAMKNLS 67 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYL 1014 H+H+ + E + + +V+EY P G L DY+ + + + +F +QI +AY+ Sbjct 68 HQHVCRLYHVIETTSK--IYMVLEYCPGGELFDYIIAKDRLSEEETRVFFRQIISALAYV 125 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H+Q Y HRDL N+L+D D +K+ DFGL A P+G + + SP + APE ++ Sbjct 126 HSQGYAHRDLKPENLLIDEDHNLKLIDFGLC-AKPKGGLGFELLTCCGSPA-YAAPELIQ 183 Query 1075 EYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + +DVWS GV LY LL + L + RG + Sbjct 184 GKAYIGSEADVWSMGVLLYALLCGFLPFDDD---------------NCMVLYRKITRG-K 227 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P L+ + + R T ++L+ Sbjct 228 YSNPHWLSPSSILLLNQMMQVDPKRRLTVKHLLD 261 Score = 172 bits (437), Expect = 2e-43, Method: Composition-based stats. Identities = 54/315 (17%), Positives = 102/315 (32%), Gaps = 39/315 (12%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-D 645 K +G G V GR ++ G +V +K++ Sbjct 11 KHYEVYETIGSGGFAKVKLGRHKLTGE------------------------KVAIKIMEK 46 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 D M +SH H+ ++ V + MV EY G L ++ + Sbjct 47 KDLGDDLPRVKIEIEAMKNLSHQHVCRLYHVIETTSKIYMVLEYCPGGELFDYIIA-KDR 105 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763 + V +Q+ SAL+Y+ ++ H ++ N+L+ +KL D G+ Sbjct 106 LSEEETRVFFRQIISALAYVHSQGYAHRDLKPENLLIDE-------DHNLKLIDFGLCAK 158 Query 764 -LGALSRE--ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 G L E + APE + G A + + D W G L + Sbjct 159 PKGGLGFELLTCCGSPAYAAPELIQGKAY-IGSEADVWSMGVLLYALLCGFLPFDDDNCM 217 Query 821 SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880 + ++ P P L +Q + +P +R + + +L ++ ++ Sbjct 218 VLYRKITRGKYSNPHWLSPSSILLLNQMMQVDPKRRLTVKHLLDHPWVMRGYSTPVEWHS 277 Query 881 NPDSPASDPTVFHKR 895 D + Sbjct 278 KYPLGHIDEDCITEM 292 >sp|O08911|MK12_MOUSE Mitogen-activated protein kinase 12 OS=Mus musculus OX=10090 GN=Mapk12 PE=1 SV=1 Length=367 Score = 212 bits (540), Expect = 2e-59, Method: Composition-based stats. Identities = 62/302 (21%), Positives = 124/302 (41%), Gaps = 36/302 (12%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLY 955 + ++ +G G +G V + TG VA+K L + +E+ +L+ + Sbjct 27 YQDLQPVGSGAYGAVC----SAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMR 82 Query 956 HEHIIKYKGCCEDQ----GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011 HE++I LVM ++ L + ++ ++ Q+ +G+ Sbjct 83 HENVIGLLDVFTPDESLDDFTDFYLVMPFM-GTDLGKLMKHETLSEDRIQFLVYQMLKGL 141 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 Y+HA IHRDL N+ ++ D +KI DFGLA+ Y V ++ APE Sbjct 142 KYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVV------TRWYRAPE 195 Query 1072 CLKEY-KFYYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGI 1114 + + ++ D+WS G + E++T + +PP +F++ + Sbjct 196 VILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKITGTPPPEFVQKLQS 255 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTV 1172 A+ + + L E LE+ + + +L++ +A R T + P +++ Sbjct 256 AEAKNYMEGLPE-LEKKDFASVLTNASPQAVNLLERMLVLDAEQRVTAAEALTHPYFESL 314 Query 1173 HE 1174 + Sbjct 315 RD 316 Score = 127 bits (318), Expect = 3e-30, Method: Composition-based stats. Identities = 34/219 (16%), Positives = 70/219 (32%), Gaps = 20/219 (9%) Query 632 DRGQELRVVLKVL-DPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPEN------ 683 D +V +K L P ++ A Y L+ + H ++ + V Sbjct 46 DSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDESLDDFTDF 105 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 +V ++ L ++ E + + Q+ L Y+ ++H ++ N+ Sbjct 106 YLVMPFM-GTDLGKLMKHE--TLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNL--- 159 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL-APECLPGGANSLSTAMDKWGFGA 802 A +K+ D G+ A S W APE + + +D W G Sbjct 160 ----AVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMR-YTQTVDIWSVGC 214 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL 841 + E+ + + + + P +L Sbjct 215 IMAEMITGKILFKGNDHLDQLKEIMKITGTPPPEFVQKL 253 >sp|Q9SSL9|PEPR1_ARATH Leucine-rich repeat receptor-like protein kinase PEPR1 OS=Arabidopsis thaliana OX=3702 GN=PEPR1 PE=1 SV=1 Length=1123 Score = 227 bits (578), Expect = 2e-59, Method: Composition-based stats. Identities = 68/305 (22%), Positives = 125/305 (41%), Gaps = 28/305 (9%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 + +G G G V G+G++ AVK L + +EID + + H Sbjct 828 NEKYTIGRGAHGIVYRASL-----GSGKVYAVKRLVFASHIRANQSMMREIDTIGKVRHR 882 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMA 1012 ++IK +G + + ++ Y+P GSL D L + + + A + G+A Sbjct 883 NLIKLEGFWLRKDDG--LMLYRYMPKGSLYDVLHGVSPKENVLDWSARYNVALGVAHGLA 940 Query 1013 YLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH +HRD+ N+L+D+D IGDFGLA+ + + + A Sbjct 941 YLHYDCHPPIVHRDIKPENILMDSDLEPHIGDFGLARLLDDS---TVSTATVTGTTGYIA 997 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR------ 1123 PE + SDV+S+GV L EL+T + + +++ + ++ Sbjct 998 PENAFKTVRGRESDVYSYGVVLLELVTRKRAVDKSFPESTDIVSWVRSALSSSNNNVEDM 1057 Query 1124 LTELLERGERLPRPDKCPCE----VYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 +T +++ D E V L +C + + + RPT + + +L+ V + Sbjct 1058 VTTIVDPILVDELLDSSLREQVMQVTELALSCTQQDPAMRPTMRDAVKLLEDVKHLARSC 1117 Query 1180 APSVF 1184 + Sbjct 1118 SSDSV 1122 Score = 163 bits (412), Expect = 2e-39, Method: Composition-based stats. Identities = 45/240 (19%), Positives = 79/240 (33%), Gaps = 45/240 (19%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + + +G+G VY L GSG +K L Sbjct 823 ATDNLNEKYTIGRGAHGIVYRASL---GSGKVY----------------------AVKRL 857 Query 645 D-PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-- 701 SH + + +V H +L + G +R + +M+ Y+ G L L Sbjct 858 VFASHIRANQSMMREIDTIGKVRHRNLIKLEGFWLRKDDGLMLYRYMPKGSLYDVLHGVS 917 Query 702 -ERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + + + + VA +A L+YL + +VH ++ NIL+ + Sbjct 918 PKENVLDWSARYNVALGVAHGLAYLHYDCHPPIVHRDIKPENILMDSDLEPH-------I 970 Query 758 SDPGVGL----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 D G+ +S ++APE D + +G LLE+ A Sbjct 971 GDFGLARLLDDSTVSTATVTGTTGYIAPENAFKTVR--GRESDVYSYGVVLLELVTRKRA 1028 >sp|Q8NG66|NEK11_HUMAN Serine/threonine-protein kinase Nek11 OS=Homo sapiens OX=9606 GN=NEK11 PE=1 SV=2 Length=645 Score = 220 bits (560), Expect = 2e-59, Method: Composition-based stats. Identities = 66/306 (22%), Positives = 118/306 (39%), Gaps = 28/306 (9%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 + A + ++ P R + LG G FG V L G V Sbjct 1 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKV- 59 Query 929 VKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 +K + + P E +L L H I+K+ +Q + ++ EY L Sbjct 60 LKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQD--NFCIITEYCEGRDLD 117 Query 988 DYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 D + + Q++ + Q+ G+ Y+H + +HRDL ++NV L N+ +KIGDF Sbjct 118 DKIQEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNL-LKIGDF 176 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 G+++ + + + +PE LK + SD+WS LYE+ Sbjct 177 GVSRLLMGSCDLATTLT---GTPHYMSPEALKHQGYDTKSDIWSLACILYEMC------- 226 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 + A L + + G+ P++ P E+ +M++ S RP+ Sbjct 227 --------CMNHAFAGSNFLSIVLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSA 278 Query 1163 ENLIPI 1168 ++ I Sbjct 279 IEILKI 284 Score = 177 bits (448), Expect = 6e-45, Method: Composition-based stats. Identities = 66/386 (17%), Positives = 116/386 (30%), Gaps = 58/386 (15%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LG G+ VY RG+EL+V LK + + Sbjct 34 KLGSGSFGTVYL--------------------VSDKKAKRGEELKV-LKEISVGELNPNE 72 Query 654 AFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER---GHVPM 708 A L+S++ H + H V ++TEY E LD ++ + P Sbjct 73 TVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPE 132 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + QL + Y+ + ++H ++ +N+ L L K+ D GV + Sbjct 133 NQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLL--------KIGDFGVSRLLMG 184 Query 769 R----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 +++PE L T D W L E+C A S S Sbjct 185 SCDLATTLTGTPHYMSPEALKH--QGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVL 242 Query 825 HFYQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT--------RLQPHNLA 875 + LPE +L + L P+ RPS IL+ + + Sbjct 243 KIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSEMT 302 Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA---VKAL 932 + + + ++ L +V A + L Sbjct 303 LEDKNLDCQKEAAHIINAMQKRIHLQTLR--ALSEVQKMTPRERMRLRKLQAADEKARKL 360 Query 933 KADCGPQHRSGWKQEIDILRTLYHEH 958 K ++ K+ ++ L + Sbjct 361 KKIVEEKYEENSKR----MQELRSRN 382 >sp|A2YNT8|SAPK2_ORYSI Serine/threonine-protein kinase SAPK2 OS=Oryza sativa subsp. indica OX=39946 GN=SAPK2 PE=2 SV=2 Length=339 Score = 211 bits (537), Expect = 2e-59, Method: Composition-based stats. Identities = 71/276 (26%), Positives = 115/276 (42%), Gaps = 26/276 (9%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 + I+D+G G+FG L + T E+ AVK + + G + ++EI R+ Sbjct 1 MERYEVIKDIGSGNFGVAKLV----RDVRTKELFAVKFI--ERGQKIDENVQREIMNHRS 54 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012 L H +I+++K L +VMEY G L + + + F QQ+ G++ Sbjct 55 LRHPNIVRFKEVVLTPTH--LAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVS 112 Query 1013 YLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 Y H+ HRDL N LLD +KI DFG +K + + + +P + AP Sbjct 113 YCHSMQICHRDLKLENTLLDGSIAPRLKICDFGYSK---SSVLHSQPKSTVGTPA-YIAP 168 Query 1071 ECLKEYKFYYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E L ++ DVWS GVTLY +L + P + + +T +L Sbjct 169 EVLARKEYDGKVADVWSCGVTLYVMLVGAYPFEDPD----------EPRNFRKTITRILS 218 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 +P + E HL+ + R T + Sbjct 219 VQYMVPDYVRVSMECRHLLSRIFVANPEQRITIPEI 254 Score = 156 bits (394), Expect = 2e-40, Method: Composition-based stats. Identities = 50/276 (18%), Positives = 87/276 (32%), Gaps = 23/276 (8%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 RD + +K ++ I + H ++ V + +V EY Sbjct 22 RDVRTKELFAVKFIERG-QKIDENVQREIMNHRSLRHPNIVRFKEVVLTPTHLAIVMEYA 80 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L + G QQL S +SY + + H ++ N LL Sbjct 81 AGGELFERI-CSAGRFSEDEARFFFQQLISGVSYCHSMQICHRDLKLENTLLD-----GS 134 Query 751 TSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +P +K+ D G ++ + V ++APE L D W G TL + Sbjct 135 IAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLARKEYD-GKVADVWSCGVTLYVM 193 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLT-------YEPTQRPS 858 G P + P E +F + R+ + P ++ +C P QR + Sbjct 194 LV-GAYPFED--PDEPRNFRKTITRILSVQYMVPDYVRVSMECRHLLSRIFVANPEQRIT 250 Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894 I L+ + +D + Sbjct 251 IPEIKNHPWFLKNLPIEMTDEYQMSVQMNDINTPSQ 286 >sp|A0A509AQE6|CDPK5_PLABA Calcium-dependent protein kinase 5 OS=Plasmodium berghei (strain Anka) OX=5823 GN=CDPK5 PE=1 SV=1 Length=562 Score = 218 bits (555), Expect = 2e-59, Method: Composition-based stats. Identities = 71/302 (24%), Positives = 116/302 (38%), Gaps = 34/302 (11%) Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932 D + ++ + K Y LG+G +G V N TG+ A+K + Sbjct 94 PYFDRSQIVQETILMNNDDLEKLYELDKYKLGKGSYGNVV----KAINKKTGQAKAIKII 149 Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992 + K+EI I++ + H +IIK ED + L LV+E G L D + + Sbjct 150 DKK-RINNIERLKREILIMKQMDHPNIIKLYEVYEDN--EKLYLVLELCTGGELFDKIVK 206 Query 993 H-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAV 1048 H S + +QI +AY H+++ IHRDL N+L +D ++I D+G A Sbjct 207 HGSFSEYETYKIMKQIFSALAYCHSKNIIHRDLKPENILYVDSSDDSPIQIIDWGFASKC 266 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 H V ++ APE LK K+ D+WS GV +Y LL Sbjct 267 MNNHNLKSV----VGTPYYIAPEILKG-KYDKKCDIWSSGVIMYILLCGYPPF------- 314 Query 1109 LELIGIAQGQMTVLRLTELLERGERL---PRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + + +++GE + K + L+ C R + Sbjct 315 --------NGKNNDDILKKVKKGEFVFDSNYWSKISLDAKELICECLNYNYKERIDVHKI 366 Query 1166 IP 1167 + Sbjct 367 VN 368 Score = 187 bits (474), Expect = 8e-49, Method: Composition-based stats. Identities = 55/319 (17%), Positives = 103/319 (32%), Gaps = 41/319 (13%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LG+G+ NV + + G +K++D + Sbjct 123 KLGKGSYGNVVKAINKKTGQAK------------------------AIKIIDKKRINNIE 158 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 +M Q+ H ++ ++ V + +V E G L + + G Sbjct 159 RLKREILIMKQMDHPNIIKLYEVYEDNEKLYLVLELCTGGELFDKIVKH-GSFSEYETYK 217 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR---E 770 + +Q+ SAL+Y +KN++H ++ NIL + I++ D G ++ + Sbjct 218 IMKQIFSALAYCHSKNIIHRDLKPENIL----YVDSSDDSPIQIIDWGFASKCMNNHNLK 273 Query 771 ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ 830 V ++APE L G D W G + I G P ++ + ++ Sbjct 274 SVVGTPYYIAPEILKG---KYDKKCDIWSSGVIMY-ILLCGYPPFNGKNNDDILKKVKKG 329 Query 831 H-----RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885 L +CL Y +R I+ ++ N + S Sbjct 330 EFVFDSNYWSKISLDAKELICECLNYNYKERIDVHKIVNHKWFIKFKNYNHITINKHLSK 389 Query 886 ASDPTVFHKRYLKKIRDLG 904 L KI+ L Sbjct 390 ELIEKFKKFHKLCKIKKLA 408 >sp|P54644|KRAC_DICDI RAC family serine/threonine-protein kinase homolog OS=Dictyostelium discoideum OX=44689 GN=pkbA PE=1 SV=1 Length=444 Score = 214 bits (546), Expect = 2e-59, Method: Composition-based stats. Identities = 65/290 (22%), Positives = 110/290 (38%), Gaps = 32/290 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960 +G+G FGKV TGE+ A+K L +H E +IL+ + H ++ Sbjct 126 VGKGSFGKV----IQVRKKDTGEVYAMKVLSKKHIVEHNEVEHTLSERNILQKINHPFLV 181 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHY 1019 Q E L +++YV G L +L + ++ + +I + +LH Sbjct 182 NLNYSF--QTEDKLYFILDYVNGGELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLSGV 239 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 I+RDL N+LL N+ + + DFGL K + APE L+ + Sbjct 240 IYRDLKPENLLLTNEGHICMTDFGLCK--EGLLTPTDKTGTFCGTPEYLAPEVLQGNGYG 297 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 D WSFG LYE+LT + + + + + +L P Sbjct 298 KQVDWWSFGSLLYEMLTGLPPFYNQDVQEMYRKIMME----------------KLSFPHF 341 Query 1140 CPCEVYHLMKNCWETEASFR---PTFENLIPILKTV--HEKYQGQAPSVF 1184 + L++ E + R P P +++ + +Q P F Sbjct 342 ISPDARSLLEQLLERDPEKRLADPNLIKRHPFFRSIDWEQLFQKNIPPPF 391 Score = 162 bits (409), Expect = 2e-41, Method: Composition-based stats. Identities = 55/317 (17%), Positives = 112/317 (35%), Gaps = 44/317 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +V + L+ +G+G+ V ++R + +G+ + Sbjct 113 EKVGVADFELLNLVGKGSFGKVI--QVRKKDTGEVY----------------------AM 148 Query 642 KVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 KVL H H+ +++ +++H L ++ + + +YV G L Sbjct 149 KVLSKKHIVEHNEVEHTLSERNILQKINHPFLVNLNYSFQTEDKLYFILDYVNGGELFYH 208 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 L++++ ++ AL +L +++ ++ N+LL G I ++ Sbjct 209 LQKDK-KFTEDRVRYYGAEIVLALEHLHLSGVIYRDLKPENLLLTNEG-------HICMT 260 Query 759 DPGVGLGAL-----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 D G+ L +LAPE L G N +D W FG+ L E+ G Sbjct 261 DFGLCKEGLLTPTDKTGTFCGTPEYLAPEVLQG--NGYGKQVDWWSFGSLLYEML-TGLP 317 Query 814 PLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 P ++ E + P P +L Q L +P +R + +++ + Sbjct 318 PFYNQDVQEMYRKIMMEKLSFPHFISPDARSLLEQLLERDPEKRLADPNLIKRHPFFRSI 377 Query 873 NLADVLTVNPDSPASDP 889 + + N P Sbjct 378 DWEQLFQKNIPPPFIPN 394 >sp|Q4PC06|HOG1_USTMA Mitogen-activated protein kinase HOG1 OS=Ustilago maydis (strain 521 / FGSC 9021) OX=237631 GN=HOG1 PE=3 SV=1 Length=358 Score = 211 bits (538), Expect = 2e-59, Method: Composition-based stats. Identities = 66/283 (23%), Positives = 109/283 (39%), Gaps = 29/283 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T VA+K + K P +E+ +L+ + HE+I Sbjct 24 QPVGMGAFGLVC----SANDQLTSTSVAIKKIMKPFSTPVLSKRTYRELKLLKHIRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 A DVWS G E+L + + EL+G ++ LR + Sbjct 192 DVAVDVWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDEVIKTICSENTLRFVQ 251 Query 1127 LLERGERLPRPD---KCPCEVYHLMKNCWETEASFRPTFENLI 1166 L + ER+P L++ + R + + Sbjct 252 SLPKRERVPFSQKFKNADPMALDLLEKMLVFDPRTRISAAEAL 294 Score = 137 bits (345), Expect = 1e-33, Method: Composition-based stats. Identities = 37/231 (16%), Positives = 76/231 (33%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 V+E D + M + D+ V +K ++ P ++ Y Sbjct 10 FGTVFE---VTTRYVDLQPVGMGAFGLVCSANDQLTSTSVAIKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHIRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + A+D W G E+ +G+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVAVDVWSAGCIFAEML-EGKPLFPGKDHVNQFSI 225 >sp|Q8CEQ0|CDKL1_MOUSE Cyclin-dependent kinase-like 1 OS=Mus musculus OX=10090 GN=Cdkl1 PE=2 SV=1 Length=352 Score = 211 bits (538), Expect = 2e-59, Method: Composition-based stats. Identities = 63/293 (22%), Positives = 118/293 (40%), Gaps = 29/293 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960 +GEG +G V + N TG++VA+K L+ + P + +EI +L+ L H +++ Sbjct 9 KIGEGSYGVV----FKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLV 64 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + + L LV EY L + + + + Q + + + H + Sbjct 65 NLLEVFRRK--RRLHLVFEYCDHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKHNC 122 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEYKF 1078 IHRD+ N+L+ +K+ DFG A+ + +YY D + ++ +PE L + ++ Sbjct 123 IHRDVKPENILITKQSAIKLCDFGFARLLTGPGDYY---TDYVATRWYRSPELLVGDTQY 179 Query 1079 YYASDVWSFGVTLYELLTHCD-----SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 DVW+ G ELL+ S + +G + + G + Sbjct 180 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVK 239 Query 1134 LPRPD----------KCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHE 1174 +P P+ +K C + + R T E L+ P ++ E Sbjct 240 IPDPEDMETLELKFPNISYSALGFLKGCLHMDPAERLTCEQLLQHPYFDSIRE 292 Score = 155 bits (391), Expect = 7e-40, Method: Composition-based stats. Identities = 49/250 (20%), Positives = 87/250 (35%), Gaps = 40/250 (16%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ ++ +G+G+ V++ R R G V +K Sbjct 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQ------------------------IVAIKRFL 36 Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + D I ++ Q+ H +L + V R +V EY +H L R +R Sbjct 37 ETEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQR 96 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 G VP + Q A+++ N +H +V NIL+ + IKL D G Sbjct 97 G-VPEPLVKNITWQTLQAVNFCHKHNCIHRDVKPENILITKQSA-------IKLCDFGFA 148 Query 764 LGAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + V + +PE L G +D W G E+ G +S Sbjct 149 RLLTGPGDYYTDYVATRWYRSPELLV-GDTQYGPPVDVWAIGCVFAELLS-GVPLWPGKS 206 Query 820 PSEKEHFYQR 829 ++ + ++ Sbjct 207 DVDQLYLIRK 216 >sp|Q7TSC3|NEK5_MOUSE Serine/threonine-protein kinase Nek5 OS=Mus musculus OX=10090 GN=Nek5 PE=2 SV=1 Length=627 Score = 219 bits (559), Expect = 2e-59, Method: Composition-based stats. Identities = 66/285 (23%), Positives = 121/285 (42%), Gaps = 33/285 (12%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 I+ +GEG FGKV L + +K + + + K E+ +L Sbjct 1 MDNFHLIKIIGEGTFGKVYL----AKDKSESSHCVIKEISL---TKEKEASKNEVILLAR 53 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEG 1010 + H +I+ + ++ G L +VMEY G L + R Q+L + QI G Sbjct 54 MEHPNIVTFFSSFQENG--RLFIVMEYCDGGDLMQRIQRQRGVMFSEDQILCWFVQISLG 111 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + ++H + +HRD+ ++N+ L + +V K+GDFG A+ + + E + + ++ + Sbjct 112 LKHIHDRKILHRDIKSQNIFLSKNGMVAKLGDFGTARTLNDSME---LAQTCAGTPYYLS 168 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE + + +D+WS G LYEL T +S L L + Sbjct 169 PEICQNRPYNNKTDIWSLGCVLYELCTLKHPFESNNFHHLVL---------------KIC 213 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTV 1172 +G P ++ L+ + RP+ +L+ P L+T+ Sbjct 214 QGRVAPISPHFSRDLQSLIPQLFRVSPQDRPSVTSLLKRPFLETL 258 Score = 175 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 48/283 (17%), Positives = 93/283 (33%), Gaps = 40/283 (14%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + +G+GT VY + D+ + V+K + Sbjct 1 MDNFHLIKIIGEGTFGKVYLAK------------------------DKSESSHCVIKEIS 36 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + A L++++ H ++ +V EY + G L ++R+RG Sbjct 37 LTKEKEASK--NEVILLARMEHPNIVTFFSSFQENGRLFIVMEYCDGGDLMQRIQRQRGV 94 Query 706 -VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + Q++ L ++ ++ ++H ++ +NI L++ G+ KL D G Sbjct 95 MFSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNGM------VAKLGDFGTAR 148 Query 765 GALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 + +L+PE + D W G L E+C + Sbjct 149 TLNDSMELAQTCAGTPYYLSPEICQN--RPYNNKTDIWSLGCVLYELCTLKHPFESNNFH 206 Query 821 SEKEHFYQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 Q R + L +L Q P RPS ++ Sbjct 207 HLVLKICQGRVAPISPHFSRDLQSLIPQLFRVSPQDRPSVTSL 249 >sp|F4KA51|LRL23_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 2.3 OS=Arabidopsis thaliana OX=3702 GN=LRK10L-2.3 PE=3 SV=2 Length=620 Score = 219 bits (558), Expect = 2e-59, Method: Composition-based stats. Identities = 63/277 (23%), Positives = 111/277 (40%), Gaps = 23/277 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V G VAVK LK + + E+ + H +I+ Sbjct 320 VGRGGFGTVYRGRLR-----DGRKVAVKVLK--DSKGNCEDFINEVASMSQTSHVNIVTL 372 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH---AQHY 1019 G C + +++ ++ E++ GSL L ++ ++ L A + G+ YLH Sbjct 373 LGFCYEGSKRA--IIYEFLENGSLDQSL---NLDVSTLYGIALGVARGLEYLHYGCKTRI 427 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL--KEYK 1077 +H D+ +NVLLD + K+ DFGLAK E E D + + APE Sbjct 428 VHFDIKPQNVLLDENLRPKVADFGLAKLC-EKQESILSLLDTRGTIGYIAPELFSRMYGS 486 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQ----SPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + SDV+S+G+ + E++ + + P + T LL G Sbjct 487 VSHKSDVYSYGMLVLEMIGARNKERVQNADPNNSSAYFPDWIYKDLENFDNTRLLGDGLT 546 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 ++ + C + S RP+ ++ +++ Sbjct 547 REEEKNA-KKMILVGLWCIQFRPSDRPSMNKVVEMME 582 Score = 202 bits (514), Expect = 1e-53, Method: Composition-based stats. Identities = 63/320 (20%), Positives = 117/320 (37%), Gaps = 66/320 (21%) Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 L ++ ++ + + +G+G VY GRLR Sbjct 300 TLRGYNYKQIKKITKSFTEVVGRGGFGTVYRGRLRDGR---------------------- 337 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 +V +KVL S + F + MSQ SH ++ + G C G + ++ E++E+G Sbjct 338 ---KVAVKVLKDSKGNC-EDFINEVASMSQTSHVNIVTLLGFCYEGSKRAIIYEFLENGS 393 Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGT 751 LD L ++ ++ +A +A L YL +VH ++ +N+LL Sbjct 394 LDQSL-----NLDVSTLYGIALGVARGLEYLHYGCKTRIVHFDIKPQNVLLDE------- 441 Query 752 SPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + K++D G+ LS + I ++APE S+S D + +G +L Sbjct 442 NLRPKVADFGLAKLCEKQESILSLLDTRGTIGYIAPELFSRMYGSVSHKSDVYSYGMLVL 501 Query 806 EIC---------------FDGEAPLQSRSPSEKEH----FYQRQHRLPEPSCPQLATLTS 846 E+ P E R E + ++ + Sbjct 502 EMIGARNKERVQNADPNNSSAYFPDWIYKDLENFDNTRLLGDGLTREEEKNAKKMILVGL 561 Query 847 QCLTYEPTQRPSFRTILRDL 866 C+ + P+ RPS ++ + Sbjct 562 WCIQFRPSDRPSMNKVVEMM 581 >sp|Q9M1G4|LRK15_ARATH Probable L-type lectin-domain containing receptor kinase I.5 OS=Arabidopsis thaliana OX=3702 GN=LECRK15 PE=2 SV=2 Length=674 Score = 220 bits (561), Expect = 2e-59, Method: Composition-based stats. Identities = 75/300 (25%), Positives = 122/300 (41%), Gaps = 22/300 (7%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 + + K R LG G FG+V + + VAVK + D G Q Sbjct 327 YGTHRFSYKSLYIATKGFHKDRFLGRGGFGEVYRG-----DLPLNKTVAVKRVSHD-GEQ 380 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIG 996 + E+ +++L H +++ G C +GE L LV EY+P GSL +L + Sbjct 381 GMKQFVAEVVSMKSLKHRNLVPLLGYCRRKGE--LLLVSEYMPNGSLDQHLFDDQSPVLS 438 Query 997 LAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 +Q + + I + YLH Q +HRD+ A NV+LD + ++GDFG+A+ G Sbjct 439 WSQRFVILKGIASALFYLHTEAEQVVLHRDIKASNVMLDAELNGRLGDFGMARFHDHGGN 498 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 V + APE + +DV++FGV L E+ + +E Sbjct 499 AATT--AAVGTVGYMAPELI-TMGASTITDVYAFGVFLLEVACGRKPVEFGVQ--VEKRF 553 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170 + + + LL+ + + P EV +MK C RP ++ L Sbjct 554 LIKWVCECWKKDSLLDAKDPRLGEEFVPEEVELVMKLGLLCTNIVPESRPAMGQVVLYLS 613 Score = 218 bits (554), Expect = 2e-58, Method: Composition-based stats. Identities = 60/305 (20%), Positives = 111/305 (36%), Gaps = 61/305 (20%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 + K + LG+G VY G L + + V +K Sbjct 339 IATKGFHKDRFLGRGGFGEVYRGDLPLNKT-------------------------VAVKR 373 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + F M + H +L + G C R E ++V+EY+ +G LD L ++ Sbjct 374 VSHDGEQGMKQFVAEVVSMKSLKHRNLVPLLGYCRRKGELLLVSEYMPNGSLDQHLFDDQ 433 Query 704 GH-VPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + + + V+ + +ASAL YL + ++H ++ N++L +L D Sbjct 434 SPVLSWSQRFVILKGIASALFYLHTEAEQVVLHRDIKASNVMLD-------AELNGRLGD 486 Query 760 PGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 G+ G + V + ++APE + GA++++ D + FG LLE+ + Sbjct 487 FGMARFHDHGGNAATTAAVGTVGYMAPELITMGASTIT---DVYAFGVFLLEVACGRKPV 543 Query 815 LQSRSPSEKEHFYQ-------------RQHRLPEPSCPQLATLTSQ----CLTYEPTQRP 857 ++ + RL E P+ L + C P RP Sbjct 544 EFGVQVEKRFLIKWVCECWKKDSLLDAKDPRLGEEFVPEEVELVMKLGLLCTNIVPESRP 603 Query 858 SFRTI 862 + + Sbjct 604 AMGQV 608 >sp|Q63538|MK12_RAT Mitogen-activated protein kinase 12 OS=Rattus norvegicus OX=10116 GN=Mapk12 PE=1 SV=1 Length=367 Score = 212 bits (539), Expect = 2e-59, Method: Composition-based stats. Identities = 62/302 (21%), Positives = 124/302 (41%), Gaps = 36/302 (12%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLY 955 + ++ +G G +G V + TG VA+K L + +E+ +L+ + Sbjct 27 YQDLQPVGSGAYGAVC----SAVDSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMR 82 Query 956 HEHIIKYKGCCEDQ----GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011 HE++I LVM ++ L + ++ ++ Q+ +G+ Sbjct 83 HENVIGLLDVFTPDETLDDFTDFYLVMPFM-GTDLGKLMKHETLSEDRIQFLVYQMLKGL 141 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 Y+HA IHRDL N+ ++ D +KI DFGLA+ Y V ++ APE Sbjct 142 KYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVV------TRWYRAPE 195 Query 1072 CLKEY-KFYYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGI 1114 + + ++ D+WS G + E++T + +PP +F++ + Sbjct 196 VILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKVTGTPPPEFVQKLQS 255 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTV 1172 A+ + + L E LE+ + + +L++ +A R T + P +++ Sbjct 256 AEAKNYMEGLPE-LEKKDFASVLTNASPQAVNLLEKMLVLDAEQRVTAAEALAHPYFESL 314 Query 1173 HE 1174 + Sbjct 315 RD 316 Score = 127 bits (319), Expect = 3e-30, Method: Composition-based stats. Identities = 34/219 (16%), Positives = 70/219 (32%), Gaps = 20/219 (9%) Query 632 DRGQELRVVLKVL-DPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPEN------ 683 D +V +K L P ++ A Y L+ + H ++ + V Sbjct 46 DSRTGNKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDF 105 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 +V ++ L ++ E + + Q+ L Y+ ++H ++ N+ Sbjct 106 YLVMPFM-GTDLGKLMKHE--TLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNL--- 159 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL-APECLPGGANSLSTAMDKWGFGA 802 A +K+ D G+ A S W APE + + +D W G Sbjct 160 ----AVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMR-YTQTVDIWSVGC 214 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL 841 + E+ + + + + P +L Sbjct 215 IMAEMITGKILFKGNDHLDQLKEIMKVTGTPPPEFVQKL 253 >sp|Q0D4J7|SAPK2_ORYSJ Serine/threonine-protein kinase SAPK2 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK2 PE=1 SV=1 Length=339 Score = 211 bits (536), Expect = 2e-59, Method: Composition-based stats. Identities = 70/276 (25%), Positives = 112/276 (41%), Gaps = 26/276 (9%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 + I+D+G G+FG L + T E+ AVK + + G + ++EI R+ Sbjct 1 MERYEVIKDIGSGNFGVAKLV----RDVRTKELFAVKFI--ERGQKIDENVQREIMNHRS 54 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012 L H +I+++K L +VMEY G L + + + F QQ+ G++ Sbjct 55 LRHPNIVRFKEVVLTPTH--LAIVMEYAAGGELFERICSAGRFSEDEARFFFQQLISGVS 112 Query 1013 YLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 Y H+ HRDL N LLD +KI DFG +K + + + AP Sbjct 113 YCHSMQICHRDLKLENTLLDGSIAPRLKICDFGYSK----SSLLHSQPKSTVGTPAYIAP 168 Query 1071 ECLKEYKFYYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E L ++ DVWS GVTLY +L + P + + +T +L Sbjct 169 EVLARKEYDGKVADVWSCGVTLYVMLVGAYPFEDPD----------EPRNFRKTITRILS 218 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 +P + E HL+ + R T + Sbjct 219 VQYMVPDYVRVSMECRHLLSRIFVANPEQRITIPEI 254 Score = 156 bits (395), Expect = 2e-40, Method: Composition-based stats. Identities = 51/276 (18%), Positives = 87/276 (32%), Gaps = 23/276 (8%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 RD + +K ++ I + H ++ V + +V EY Sbjct 22 RDVRTKELFAVKFIERG-QKIDENVQREIMNHRSLRHPNIVRFKEVVLTPTHLAIVMEYA 80 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L + G QQL S +SY + + H ++ N LL Sbjct 81 AGGELFERI-CSAGRFSEDEARFFFQQLISGVSYCHSMQICHRDLKLENTLLD-----GS 134 Query 751 TSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +P +K+ D G +L + V ++APE L D W G TL + Sbjct 135 IAPRLKICDFGYSKSSLLHSQPKSTVGTPAYIAPEVLARKEYD-GKVADVWSCGVTLYVM 193 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLT-------YEPTQRPS 858 G P + P E +F + R+ + P ++ +C P QR + Sbjct 194 LV-GAYPFED--PDEPRNFRKTITRILSVQYMVPDYVRVSMECRHLLSRIFVANPEQRIT 250 Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894 I L+ + +D + Sbjct 251 IPEIKNHPWFLKNLPIEMTDEYQMSVQMNDINTPSQ 286 >sp|Q2RBF0|CIPKF_ORYSJ CBL-interacting protein kinase 15 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK15 PE=2 SV=1 Length=434 Score = 214 bits (544), Expect = 2e-59, Method: Composition-based stats. Identities = 61/267 (23%), Positives = 113/267 (42%), Gaps = 27/267 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960 LG+G FGKV N + + VA+K + + ++EI +R + H++I+ Sbjct 18 LGKGTFGKVHY----ARNLESNQSVAIKMMDKQQILKVGLSEQIRREITTMRLVAHKNIV 73 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + + + + VMEYV G L + + R + + QQ+ + Y H++ Sbjct 74 QLHEVMATRNK--IYFVMEYVKGGELFEKVAKRGKLTEVVAHKYFQQLISAVDYCHSRGV 131 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 HRDL N+LLD + +K+ DFGL+ + + +P + APE + + + Sbjct 132 YHRDLKPENLLLDENENLKVSDFGLSALSESKRQDGLLHTTCGTPA-YVAPEVISKIGYD 190 Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SD+WS GV L+ L+ Q P ++ + ++ GE P Sbjct 191 GAKSDIWSCGVILFVLVAGYLPFQGP---------------NLMEMYRKIQHGE-FRCPG 234 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENL 1165 ++ L+ + S R + + + Sbjct 235 WFSRKLQKLLYKIMDPNPSTRISIQKI 261 Score = 181 bits (458), Expect = 6e-48, Method: Composition-based stats. Identities = 56/296 (19%), Positives = 100/296 (34%), Gaps = 44/296 (15%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 ++ + LG+GT V+ R V +K Sbjct 6 KILMERYELGRLLGKGTFGKVHYARNLESNQS------------------------VAIK 41 Query 643 VLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 ++D ++ + M V+H ++ +H V + V EYV+ G L + Sbjct 42 MMDKQQILKVGLSEQIRREITTMRLVAHKNIVQLHEVMATRNKIYFVMEYVKGGELFEKV 101 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 +RG + QQL SA+ Y ++ + H ++ N+LL + +K+SD Sbjct 102 -AKRGKLTEVVAHKYFQQLISAVDYCHSRGVYHRDLKPENLLLDE-------NENLKVSD 153 Query 760 PGVGLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ + S+ ++APE + D W G L + G Sbjct 154 FGLSALSESKRQDGLLHTTCGTPAYVAPEVISKIGYD-GAKSDIWSCGVIL-FVLVAGYL 211 Query 814 PLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 P Q + E + R P +L L + + P+ R S + I Sbjct 212 PFQGPNLMEMYRKIQHGEFRCPGWFSRKLQKLLYKIMDPNPSTRISIQKIKESTWF 267 >sp|Q96PY6|NEK1_HUMAN Serine/threonine-protein kinase Nek1 OS=Homo sapiens OX=9606 GN=NEK1 PE=1 SV=2 Length=1258 Score = 227 bits (578), Expect = 2e-59, Method: Composition-based stats. Identities = 63/278 (23%), Positives = 121/278 (44%), Gaps = 28/278 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILR 952 +++ +GEG FGK L + G +K + + + R ++E+ +L Sbjct 1 MEKYVRLQKIGEGSFGKAILV----KSTEDGRQYVIKEINISRMSSKEREESRREVAVLA 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICE 1009 + H +I++Y+ E+ G SL +VM+Y G L + Q+L + QIC Sbjct 57 NMKHPNIVQYRESFEENG--SLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICL 114 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + ++H + +HRD+ ++N+ L D V++GDFG+A+ + E R ++ + Sbjct 115 ALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELART---CIGTPYYLS 171 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE + + SD+W+ G LYEL T + ++ K L L + Sbjct 172 PEICENKPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVL---------------KII 216 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 G P ++ L+ ++ RP+ +++ Sbjct 217 SGSFPPVSLHYSYDLRSLVSQLFKRNPRDRPSVNSILE 254 Score = 160 bits (404), Expect = 2e-38, Method: Composition-based stats. Identities = 44/283 (16%), Positives = 92/283 (33%), Gaps = 37/283 (13%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ +L +G+G+ LV + G++ + + Sbjct 1 MEKYVRLQKIGEGSFGK----------------------AILVKSTEDGRQYVIKEINIS 38 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 ++++ + H ++ +V +Y E G L + ++G Sbjct 39 RMSSKEREESRREVAVLANMKHPNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGV 98 Query 706 V-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + Q+ AL ++ ++ ++H ++ +NI L + G ++L D G+ Sbjct 99 LFQEDQILDWFVQICLALKHVHDRKILHRDIKSQNIFLTKDG-------TVQLGDFGIAR 151 Query 765 GALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS-RS 819 S + +L+PE + D W G L E+C A Sbjct 152 VLNSTVELARTCIGTPYYLSPEICEN--KPYNNKSDIWALGCVLYELCTLKHAFEAGSMK 209 Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 + + L +L SQ P RPS +I Sbjct 210 NLVLKIISGSFPPVSLHYSYDLRSLVSQLFKRNPRDRPSVNSI 252 >sp|Q6C7U8|PHO85_YARLI Negative regulator of the PHO system OS=Yarrowia lipolytica (strain CLIB 122 / E 150) OX=284591 GN=PHO85 PE=3 SV=1 Length=294 Score = 209 bits (532), Expect = 3e-59, Method: Composition-based stats. Identities = 54/217 (25%), Positives = 99/217 (46%), Gaps = 15/217 (7%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 + +++ LGEG + V Y N TG++VA+K + D S +EI + Sbjct 1 MNTSSQFQQLEKLGEGTYATV----YKGRNRTTGQLVALKEINLDSEEGTPSTAIREISL 56 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQ 1006 ++ L HE+I+ E L LV EY+ L+ ++ + ++ Q+ F Q Sbjct 57 MKELKHENIVTLYDVI--HTENKLNLVFEYMDK-DLKKFMDTNGNKGALETKQVKWFMYQ 113 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 + G+ + H +HRDL +N+L++ +K+ DFGLA+A + ++ Sbjct 114 LLRGILFCHDNRVLHRDLKPQNLLINAKGQLKLADFGLARAFGIP---VNTFSNEVVTLW 170 Query 1067 WYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQ 1102 + AP+ L + + + D+WS G + E+ T Sbjct 171 YRAPDVLLGSRTYSTSIDIWSAGCIMAEMFTGRPLFP 207 Score = 175 bits (444), Expect = 2e-47, Method: Composition-based stats. Identities = 56/322 (17%), Positives = 121/322 (38%), Gaps = 40/322 (12%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + QL LG+GT VY+GR R G V LK ++ Sbjct 5 SQFQQLEKLGEGTYATVYKGRNRTTGQ------------------------LVALKEINL 40 Query 647 SHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR--RER 703 + SLM ++ H ++ ++ V + +V EY++ L ++ + Sbjct 41 DSEEGTPSTAIREISLMKELKHENIVTLYDVIHTENKLNLVFEYMDK-DLKKFMDTNGNK 99 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 G + QL + + + ++H ++ +N+L+ G +KL+D G+ Sbjct 100 GALETKQVKWFMYQLLRGILFCHDNRVLHRDLKPQNLLINAKGQ-------LKLADFGLA 152 Query 764 LG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + V + + AP+ L G+ + ST++D W G + E+ S + Sbjct 153 RAFGIPVNTFSNEVVTLWYRAPDVLL-GSRTYSTSIDIWSAGCIMAEMFTGRPLFPGSSN 211 Query 820 PSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 + +H ++ E + P +++L + ++ R I+ + + L +L Sbjct 212 DDQLQHIFKLMGTPNESTWPNISSLPNYRSNFQVYAPQDLRVIIPQIDNVALDLLLSLLQ 271 Query 880 VNPDSPASDPTVFHKRYLKKIR 901 + P++ + + + Sbjct 272 LKPENRITARQSLEHPWFAEYH 293 >sp|Q9HFW2|CLA4_EREGS Serine/threonine-protein kinase CLA4 OS=Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=CLA4 PE=3 SV=1 Length=793 Score = 223 bits (567), Expect = 3e-59, Method: Composition-based stats. Identities = 72/301 (24%), Positives = 119/301 (40%), Gaps = 40/301 (13%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT--------------NDGTGEMVAVKALKA 934 + + I G+G G V L ND G+ VA+K + Sbjct 490 FNTDPSPFFQMIEKAGQGASGSVYLAQRLKIPPYDENSGVSQHELNDNIGDKVAIKQMIL 549 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH- 993 P+ + EI +++ H++I+ + + E L +VMEY+ GSL D + Sbjct 550 SKQPR-KELIVNEILVMKDSQHKNIVNFLEAYL-KTEDDLWVVMEYMEGGSLTDVIENSI 607 Query 994 -------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 + Q+ ++ C+G+ +LH +H IHRD+ + NVLLD VKI DFG Sbjct 608 GSDASESPMTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTHGRVKITDFGFCA 667 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 + + R +W APE +K+ ++ DVWS G+ E+L PP Sbjct 668 KLTDKR---SKRATMVGTPYWMAPEVVKQREYDEKVDVWSLGIMTIEML-----EGEPPY 719 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 E + T +L P+ E+ + C + +R + E L+ Sbjct 720 LNEEPLKALYLIATNGT--------PKLKHPELLSLEIKRFLSVCLCVDVRYRASTEELL 771 Query 1167 P 1167 Sbjct 772 H 772 Score = 192 bits (488), Expect = 3e-49, Method: Composition-based stats. Identities = 55/314 (18%), Positives = 103/314 (33%), Gaps = 31/314 (10%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L+ ++F+ + GQG +VY + D G E G Sbjct 485 LAAVTFNTDPSPFFQMIEKAGQGASGSVYLAQRLKIPPYDENSGVSQHELNDNIGD---- 540 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGP 694 +V +K + S +M H ++ ++ + +V EY+E G Sbjct 541 --KVAIKQMILSKQPRKELIVNEILVMKDSQHKNIVNFLEAYLKTEDDLWVVMEYMEGGS 598 Query 695 LDVWLRRE------RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 L + + + ++ L +L +K+++H ++ N+LL G Sbjct 599 LTDVIENSIGSDASESPMTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTHGR- 657 Query 749 EGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 +K++D G R V W+APE + +D W G Sbjct 658 ------VKITDFGFCAKLTDKRSKRATMVGTPYWMAPEVVKQ--REYDEKVDVWSLGIMT 709 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQH----RLPEPSCPQLATLTSQCLTYEPTQRPSFR 860 +E+ +GE P + P + + + PE ++ S CL + R S Sbjct 710 IEML-EGEPPYLNEEPLKALYLIATNGTPKLKHPELLSLEIKRFLSVCLCVDVRYRASTE 768 Query 861 TILRDLTRLQPHNL 874 +L Sbjct 769 ELLHHSFFETSCEP 782 >sp|A8X6H4|CMK1_CAEBR Calcium/calmodulin-dependent protein kinase type 1 OS=Caenorhabditis briggsae OX=6238 GN=cmk-1 PE=3 SV=4 Length=356 Score = 211 bits (537), Expect = 3e-59, Method: Composition-based stats. Identities = 64/265 (24%), Positives = 101/265 (38%), Gaps = 34/265 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G F KV L G++ AVK + + EI +LR L H +I++ Sbjct 28 LGTGAFSKVFLAESK---TDVGQLYAVKCIDKKALKGKEESLENEIKVLRKLRHNNIVQL 84 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 +++ + + LVME V G L D + + S +Q+ E ++++H +H Sbjct 85 FETYDEK--QFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAVSFMHDNGVVH 142 Query 1022 RDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 RDL N+L D D + I DFGL+K G V + APE L++ + Sbjct 143 RDLKPENLLYYNQDEDSKIMISDFGLSKTEDSG-----VMATACGTPGYVAPEVLQQKPY 197 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP- 1137 A DVWS GV Y LL + ++++ P Sbjct 198 GKAVDVWSIGVIAYILLCGYPPF--------------YDESDANLFAQIIKGEYEFDAPY 243 Query 1138 -DKCPCEVYHLM--KNCWETEASFR 1159 D+ + C + R Sbjct 244 WDQISDSAKDFISHLMCC--DPEMR 266 Score = 154 bits (390), Expect = 1e-39, Method: Composition-based stats. Identities = 45/308 (15%), Positives = 91/308 (30%), Gaps = 35/308 (11%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 +++ LG G + V+ D GQ +K +D Sbjct 19 REKYDFRDVLGTGAFSKVFLA---------------------ESKTDVGQ--LYAVKCID 55 Query 646 PSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 ++ ++ H ++ + +V E V G L + +G Sbjct 56 KKALKGKEESLENEIKVLRKLRHNNIVQLFETYDEKQFVYLVMELVTGGELFDRI-VAKG 114 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + +Q+ A+S++ + +VH ++ N+L + I +SD G+ Sbjct 115 SYTEQDASNLIRQVLEAVSFMHDNGVVHRDLKPENLL----YYNQDEDSKIMISDFGLSK 170 Query 765 GALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 S ++APE L A+D W G I G P S + Sbjct 171 TEDSGVMATACGTPGYVAPEVLQQ--KPYGKAVDVWSIGVIAY-ILLCGYPPFYDESDAN 227 Query 823 KEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 + + P Q++ +++ P R + + T + Sbjct 228 LFAQIIKGEYEFDAPYWDQISDSAKDFISHLMCCDPEMRFTCQSALEHPWISGNTAYTHD 287 Query 882 PDSPASDP 889 + Sbjct 288 IHRTVAVH 295 >sp|O14965|AURKA_HUMAN Aurora kinase A OS=Homo sapiens OX=9606 GN=AURKA PE=1 SV=3 Length=403 Score = 213 bits (541), Expect = 3e-59, Method: Composition-based stats. Identities = 63/290 (22%), Positives = 110/290 (38%), Gaps = 30/290 (10%) Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQ 939 + S + + R LG+G FG V L + ++A+K L KA Sbjct 117 KQKNEESKKRQWALEDFEIGRPLGKGKFGNVYL----AREKQSKFILALKVLFKAQLEKA 172 Query 940 HRS-GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGL 997 ++E++I L H +I++ G D + L++EY PLG++ L + Sbjct 173 GVEHQLRREVEIQSHLRHPNILRLYGYFHDAT--RVYLILEYAPLGTVYRELQKLSKFDE 230 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 + + ++ ++Y H++ IHRD+ N+LL + +KI DFG + P Sbjct 231 QRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSR----- 285 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 R + + PE ++ D+WS GV YE L ++ Sbjct 286 RTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEA-------------- 331 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 T + + R E PD L+ + S RP ++ Sbjct 332 -NTYQETYKRISRVE-FTFPDFVTEGARDLISRLLKHNPSQRPMLREVLE 379 Score = 186 bits (471), Expect = 7e-50, Method: Composition-based stats. Identities = 57/301 (19%), Positives = 109/301 (36%), Gaps = 41/301 (14%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 ++ LG+G NVY R++ + + LKVL Sbjct 131 EDFEIGRPLGKGKFGNVYLA------------------------REKQSKFILALKVLFK 166 Query 647 SHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + + + + S + H ++ ++G ++ EY G + L++ Sbjct 167 AQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKL- 225 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 +LA+ALSY +K ++H ++ N+LL G++ +K++D G Sbjct 226 SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLL-------GSAGELKIADFGWS 278 Query 764 LGALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + A S R + +L PE + G + +D W G E G+ P ++ + Sbjct 279 VHAPSSRRTTLCGTLDYLPPEMIEGRMH--DEKVDLWSLGVLCYEFLV-GKPPFEANTYQ 335 Query 822 EKEH-FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880 E + + P+ L S+ L + P+QRP R +L + Sbjct 336 ETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQN 395 Query 881 N 881 Sbjct 396 K 396 >sp|Q54SJ5|MYLKC_DICDI Probable myosin light chain kinase DDB_G0282429 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0282429 PE=3 SV=1 Length=312 Score = 209 bits (533), Expect = 3e-59, Method: Composition-based stats. Identities = 70/271 (26%), Positives = 106/271 (39%), Gaps = 32/271 (12%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHI 959 ++G G F V + T+ TG VA+K++ +EI+I++ + H +I Sbjct 42 NEIGRGAFSIVR----EATSRATGTKVAIKSINTRFIKN--KLLMREIEIMKKVGDHPNI 95 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQH 1018 +K E K L LV+E V G L D + R +QI + +LHA Sbjct 96 LKLYEVYE--TTKHLHLVLELVTGGELFDKIVQRGEYSEQDASKIVRQIVSAVGHLHANG 153 Query 1019 YIHRDLAARNVLL--DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 HRDL +N+L + +++ DFGL+K +G E + APE L+ Sbjct 154 IAHRDLKPQNLLCAGEEGDDIRVADFGLSKIFGDGDYL----ETCCGSPEYVAPEVLECK 209 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER-GERLP 1135 + A D+WS GV Y LLT C L E + P Sbjct 210 PYDKACDLWSVGVITYVLLTGCFPF---------------WDKNNAVLYEKIRNVDYGWP 254 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + E L+ + E R TFE + Sbjct 255 EGLEVSNEAKDLVSHLIEKNPEKRFTFEQCL 285 Score = 155 bits (392), Expect = 2e-40, Method: Composition-based stats. Identities = 49/287 (17%), Positives = 92/287 (32%), Gaps = 41/287 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + +G+G + V E R G +V +K ++ + Sbjct 37 NYILGNEIGRGAFSIVREATSRATG------------------------TKVAIKSIN-T 71 Query 648 HHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 +M +V H ++ ++ V +V E V G L + +RG Sbjct 72 RFIKNKLLMREIEIMKKVGDHPNILKLYEVYETTKHLHLVLELVTGGELFDKI-VQRGEY 130 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-- 764 + +Q+ SA+ +L + H ++ +N+L A + I+++D G+ Sbjct 131 SEQDASKIVRQIVSAVGHLHANGIAHRDLKPQNLLCAGEEGDD-----IRVADFGLSKIF 185 Query 765 -GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS-- 821 E ++APE L A D W G + G P ++ + Sbjct 186 GDGDYLETCCGSPEYVAPEVLE--CKPYDKACDLWSVGVITY-VLLTGCFPFWDKNNAVL 242 Query 822 -EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 EK + L S + P +R +F L Sbjct 243 YEKIRNVDYGWPEGLEVSNEAKDLVSHLIEKNPEKRFTFEQCLIHPW 289 >sp|Q8VCT9|TESK2_MOUSE Dual specificity testis-specific protein kinase 2 OS=Mus musculus OX=10090 GN=Tesk2 PE=1 SV=1 Length=570 Score = 218 bits (554), Expect = 3e-59, Method: Composition-based stats. Identities = 71/285 (25%), Positives = 124/285 (44%), Gaps = 33/285 (12%) Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 +G G F +V + + +G+++A+K + +R+ +E+ ++ L H Sbjct 59 FTREKIGSGFFSEV----FKVRHRASGQVMALKM---NTLSSNRANLLKEMQLMNRLSHP 111 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHA 1016 +I+++ G C QG+ L + EY+ G+L L + + A I G++YLH Sbjct 112 NILRFMGVCVHQGQ--LHALTEYINSGNLEQLLDSDLYLPWTVRVKLAYDIAVGLSYLHF 169 Query 1017 QHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + HRDL ++N L+ D + DFGLA+ +P+ R + FW APE L Sbjct 170 KGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDA-SIGREKLAVVGSPFWMAPEVL 228 Query 1074 KEYKFYYASDVWSFGVTLYELLTH--CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 ++ + +DV+S+G+ L E++ D P T+ L A M Sbjct 229 RDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVG---------- 278 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKY 1176 CP + L NC + RP+FE + LK + + Sbjct 279 -------DCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLKEIMSRL 316 Score = 192 bits (489), Expect = 1e-50, Method: Composition-based stats. Identities = 65/314 (21%), Positives = 116/314 (37%), Gaps = 40/314 (13%) Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 ++ R S + +F R+ + +G G + V++ R R Sbjct 33 VQVGRVSSSSYRAIISAFSRLTSLDDFTREKIGSGFFSEVFKVRHRA------------- 79 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 GQ + + + L + ++ + LM+++SH ++ GVCV + Sbjct 80 ---------SGQVMALKMNTLSSNRANL----LKEMQLMNRLSHPNILRFMGVCVHQGQL 126 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 +TEY+ G L+ L ++P ++ +A +A LSYL K + H ++ +N L+ Sbjct 127 HALTEYINSGNLEQLL-DSDLYLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSKNCLIK 185 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDK 797 R + ++D G+ V W+APE L + D Sbjct 186 R----DENGYSAVVADFGLAEKIPDASIGREKLAVVGSPFWMAPEVLRD--EPYNEKADV 239 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP-QLATLTSQCLTYEPTQR 856 + +G L EI +A +E + CP LT C +P R Sbjct 240 FSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQNMVGDCPSDFLQLTFNCCNMDPKLR 299 Query 857 PSFRTILRDLTRLQ 870 PSF I + L + Sbjct 300 PSFEEIGKTLKEIM 313 >sp|Q60855|RIPK1_MOUSE Receptor-interacting serine/threonine-protein kinase 1 OS=Mus musculus OX=10090 GN=Ripk1 PE=1 SV=1 Length=656 Score = 219 bits (559), Expect = 3e-59, Method: Composition-based stats. Identities = 72/287 (25%), Positives = 120/287 (42%), Gaps = 33/287 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG-PQHRSGWKQEIDILRTLYHEHII 960 DL G FGKVSL + V +K + ++ +E ++ L H ++ Sbjct 22 DLDSGGFGKVSLCYHRSHG-----FVILKKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVV 76 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHY 1019 K G ++G + LVMEY+ G+L L + L+ + EGM YLH + Sbjct 77 KLLGIIIEEG--NYSLVMEYMEKGNLMHVLKTQIDVPLSLKGRIIVEAIEGMCYLHDKGV 134 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLA-----------KAVPEGHEYYRVREDGDSPVFWY 1068 IH+DL N+L+D D +KI D G+A K + +++ +++ Sbjct 135 IHKDLKPENILVDRDFHIKIADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYM 194 Query 1069 APECLKE--YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 APE L + K SDV+SFG+ L+ + + ++ +I I G + Sbjct 195 APEHLNDINAKPTEKSDVYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNRPNVE--- 251 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 + CP E+ LM+ CW+ RPTF + + + Sbjct 252 --------EILEYCPREIISLMERCWQAIPEDRPTFLGIEEEFRPFY 290 Score = 187 bits (475), Expect = 2e-48, Method: Composition-based stats. Identities = 58/326 (18%), Positives = 117/326 (36%), Gaps = 60/326 (18%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 L ++ ++ + + L G V R G Sbjct 6 SLDNIKMASSDLLEKTDLDSGGFGKVSLCYHRSHGF------------------------ 41 Query 638 RVVLKVL--DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V+LK + P+ + E +M ++ H+ + + G+ + +V EY+E G L Sbjct 42 -VILKKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVVKLLGIIIEEGNYSLVMEYMEKGNL 100 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 L+ + VP++ K + + + YL +K ++H ++ NIL+ R I Sbjct 101 MHVLKTQ-IDVPLSLKGRIIVEAIEGMCYLHDKGVIHKDLKPENILVDR-------DFHI 152 Query 756 KLSDPGVG------------------LGALSREERVERIPWLAPECLPGGANSLSTAMDK 797 K++D GV + + +++ + ++APE L + D Sbjct 153 KIADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMAPEHLNDINAKPTEKSDV 212 Query 798 WGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP------EPSCPQLATLTSQCLTY 851 + FG L I F + P ++ +E+ + P E ++ +L +C Sbjct 213 YSFGIVLWAI-FAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPREIISLMERCWQA 271 Query 852 EPTQRPSFRTILRDLTRLQPHNLADV 877 P RP+F I + + + Sbjct 272 IPEDRPTFLGIEEEFRPFYLSHFEEY 297 >sp|Q2QYM3|CIPKE_ORYSJ CBL-interacting protein kinase 14 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK14 PE=2 SV=1 Length=439 Score = 214 bits (544), Expect = 3e-59, Method: Composition-based stats. Identities = 61/267 (23%), Positives = 113/267 (42%), Gaps = 27/267 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960 LG+G FGKV N + + VA+K + + ++EI +R + H++I+ Sbjct 18 LGKGTFGKVHY----ARNLESNQSVAIKMMDKQQVLKVGLSEQIRREITTMRLVAHKNIV 73 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + + + + VMEYV G L + + R + + QQ+ + Y H++ Sbjct 74 QLHEVMATRNK--IYFVMEYVKGGELFEKVAKRGKLTEVVAHKYFQQLISAVDYCHSRGV 131 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 HRDL N+LLD + +K+ DFGL+ + + +P + APE + + + Sbjct 132 YHRDLKPENLLLDENENLKVSDFGLSALSESKRQDGLLHTTCGTPA-YVAPEVISKIGYD 190 Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SD+WS GV L+ L+ Q P ++ + ++ GE P Sbjct 191 GAKSDIWSCGVILFVLVAGYLPFQGP---------------NLMEMYRKIQHGE-FRCPG 234 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENL 1165 ++ L+ + S R + + + Sbjct 235 WFSRKLQKLLYKIMDPNPSTRISIQKI 261 Score = 181 bits (458), Expect = 7e-48, Method: Composition-based stats. Identities = 56/296 (19%), Positives = 100/296 (34%), Gaps = 44/296 (15%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 ++ + LG+GT V+ R V +K Sbjct 6 KILMERYELGRLLGKGTFGKVHYARNLESNQS------------------------VAIK 41 Query 643 VLDPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 ++D ++ + M V+H ++ +H V + V EYV+ G L + Sbjct 42 MMDKQQVLKVGLSEQIRREITTMRLVAHKNIVQLHEVMATRNKIYFVMEYVKGGELFEKV 101 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 +RG + QQL SA+ Y ++ + H ++ N+LL + +K+SD Sbjct 102 -AKRGKLTEVVAHKYFQQLISAVDYCHSRGVYHRDLKPENLLLDE-------NENLKVSD 153 Query 760 PGVGLGALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 G+ + S+ ++APE + D W G L + G Sbjct 154 FGLSALSESKRQDGLLHTTCGTPAYVAPEVISKIGYD-GAKSDIWSCGVIL-FVLVAGYL 211 Query 814 PLQSRSPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 P Q + E + R P +L L + + P+ R S + I Sbjct 212 PFQGPNLMEMYRKIQHGEFRCPGWFSRKLQKLLYKIMDPNPSTRISIQKIKESTWF 267 >sp|Q924X7|STK33_MOUSE Serine/threonine-protein kinase 33 OS=Mus musculus OX=10090 GN=Stk33 PE=1 SV=2 Length=491 Score = 215 bits (548), Expect = 3e-59, Method: Composition-based stats. Identities = 79/380 (21%), Positives = 150/380 (39%), Gaps = 45/380 (12%) Query 804 LLEICFDGEAPLQSRSPSEK-----EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPS 858 LL +C G++P+ S+ F+ Q R E + + ++L + S Sbjct 23 LLCVCPAGKSPVLVVEMSQTSSIGSTEFFASQERKKERNTSRESSL----------KDLS 72 Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918 RT + + ++V D + + R LG+G FG V ++ Sbjct 73 IRTSNVERKPQAQWSRSNVTVGKIPHIRMDDGAGIEEFYTFGRILGQGSFGMV----FEA 128 Query 919 TNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLV 977 + TG A+K + + G ++E+ IL+T+ H+HII + E + + LV Sbjct 129 IDKETGAKWAIKKVNKEKAGSSAMKLLEREVSILKTVNHQHIIHLEQVFESP--QKMYLV 186 Query 978 MEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN--- 1033 ME G L+ + R + L Q + +AYLH + +HRDL N+++ + Sbjct 187 MELCEDGELKAVMDQRGHFSENETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFI 246 Query 1034 ------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 + +K+ DFGL+ ++ +P+ + APE + + + D+WS Sbjct 247 DDNNEMNLNIKVTDFGLSVQKHGSRSEGMMQTTCGTPI-YMAPEVINAHDYSQQCDIWSI 305 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 GV ++ LL +A + + L + E P + + Sbjct 306 GVIMFILLCGEPPF------------LANSEEKLYELIKKGELRFENPVWESVSDSAKNT 353 Query 1148 MKNCWETEASFRPTFENLIP 1167 +K + + + R T + L+ Sbjct 354 LKQLMKVDPAHRITAKELLD 373 Score = 183 bits (465), Expect = 3e-48, Method: Composition-based stats. Identities = 58/291 (20%), Positives = 111/291 (38%), Gaps = 39/291 (13%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 T LGQG+ V+E + G+ + ++ +K+L+ Sbjct 112 TFGRILGQGSFGMVFEAIDKETGAKWAIKKVNKEKAGSS-----------AMKLLE---- 156 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 S++ V+H H+ + V + +V E E G L + +RGH Sbjct 157 -------REVSILKTVNHQHIIHLEQVFESPQKMYLVMELCEDGELKAVM-DQRGHFSEN 208 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG--TSPFIKLSDPGV----- 762 ++ Q LASA++YL NK++VH ++ NI++ + + + IK++D G+ Sbjct 209 ETRLIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDDNNEMNLNIKVTDFGLSVQKH 268 Query 763 -GLGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + ++APE + A+ S D W G + I GE P + S Sbjct 269 GSRSEGMMQTTCGTPIYMAPEVI--NAHDYSQQCDIWSIGVIM-FILLCGEPPFLANSEE 325 Query 822 EKEHFYQRQ-----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + ++ + + E Q + +P R + + +L + Sbjct 326 KLYELIKKGELRFENPVWESVSDSAKNTLKQLMKVDPAHRITAKELLDNQW 376 >sp|P34892|KIN16_CAEEL Receptor-like tyrosine-protein kinase kin-16 OS=Caenorhabditis elegans OX=6239 GN=kin-16 PE=2 SV=1 Length=495 Score = 215 bits (548), Expect = 3e-59, Method: Composition-based stats. Identities = 88/323 (27%), Positives = 126/323 (39%), Gaps = 70/323 (22%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEM------VAVKALKADCGPQHRSGWKQEIDILRTL-Y 955 LG G+FG V + E VAVK+ S E+ ++ ++ Sbjct 146 LGSGNFGVVRKGILKMASPKNEEEKKMRLTVAVKSAANCYDISQTSMLAAELRLMCSIGR 205 Query 956 HEHIIKYKGCCEDQGEK-SLQLVMEYVPLGSLRDYLPRH--------------------- 993 +++ G + K L +V EY+ G +R YL H Sbjct 206 FPNVLALVGAVTSELRKGRLLIVTEYIDCGDIRKYLIDHRNVFQDHLIEDKTEPDSYLTP 265 Query 994 --------------------------SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027 S+ + LL F QI GM YL + +HRDLA R Sbjct 266 ISAKRKNYVFKNTDENSDYVIKESLDSLTTSDLLSFGLQIANGMQYLASIPMVHRDLALR 325 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYY-RVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 NVLL ++ ++I DFG+A+ Y + +D PV W +PE KF SDVWS Sbjct 326 NVLLKKNKTIRIADFGMARTHENKSYYIPQKTKDAPVPVRWMSPEAFDTMKFTEKSDVWS 385 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 FG+ LYE+ T L + + R+ E + G R P+P C E+Y Sbjct 386 FGICLYEIFT--------------LGQLPYPDVPSERIYEYMHSGRRCPQPQHCHVELYD 431 Query 1147 LMKNCWETEASFRPTFENLIPIL 1169 LMK CW + RP F N + Sbjct 432 LMKLCWHEKPELRPNFSNCVEYF 454 Score = 177 bits (449), Expect = 3e-46, Method: Composition-based stats. Identities = 61/355 (17%), Positives = 112/355 (32%), Gaps = 83/355 (23%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L + + + + S LG G V +G L++ + EE KM Sbjct 127 LPYKKQYEIASENLENKSILGSGNFGVVRKGILKMASPKNEEEKKMR------------- 173 Query 636 ELRVVLKVLDPSHHDIALAFYE-TASLMSQV-SHTHLAFVHGVCV---RGPENIMVTEYV 690 L V +K + + LM + ++ + G R ++VTEY+ Sbjct 174 -LTVAVKSAANCYDISQTSMLAAELRLMCSIGRFPNVLALVGAVTSELRKGRLLIVTEYI 232 Query 691 EHGPLDVWLRRERG---------------------------------------------H 705 + G + +L R Sbjct 233 DCGDIRKYLIDHRNVFQDHLIEDKTEPDSYLTPISAKRKNYVFKNTDENSDYVIKESLDS 292 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 + + + Q+A+ + YL + +VH ++ RN+LL + + I+++D G+ Sbjct 293 LTTSDLLSFGLQIANGMQYLASIPMVHRDLALRNVLLKK-------NKTIRIADFGMART 345 Query 766 ALSREERV--------ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 ++ + + W++PE + D W FG L EI G+ P Sbjct 346 HENKSYYIPQKTKDAPVPVRWMSPEAFDTM--KFTEKSDVWSFGICLYEIFTLGQLPYPD 403 Query 818 RSPSEKEHFYQRQHRLPEPSCPQ--LATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + R P+P L L C +P RP+F + Sbjct 404 VPSERIYEYMHSGRRCPQPQHCHVELYDLMKLCWHEKPELRPNFSNCVEYFIGHM 458 >sp|P25848|PHY1_CERPU Light-sensor Protein kinase OS=Ceratodon purpureus OX=3225 GN=PHY1 PE=3 SV=3 Length=1307 Score = 227 bits (578), Expect = 4e-59, Method: Composition-based stats. Identities = 79/384 (21%), Positives = 135/384 (35%), Gaps = 69/384 (18%) Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 + LT + L+ + + + + + + + ++++ Sbjct 948 IYDLTEKTLSSDQNDLAIYLLQRLKRAKPILPSFSSRPSWWNFYDDWSFSEKFFQWIQIT 1007 Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG G V + G VA K ++ +K+E++IL L H +I Sbjct 1008 GSLGSGSSATVEKAVWL------GTPVAKKTFYG----RNNEDFKREVEILAELCHPNIT 1057 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH----------SIGLAQLLLFAQQICEG 1010 C + ++ME + G L + R + +++ Q EG Sbjct 1058 SM--FCSPLYRRKCSIIMELMD-GDLLALMQRRLDRNEDHDSPPFSILEVVDIILQTSEG 1114 Query 1011 MAYLHAQHYIHRDLAARNVLLDN---------DRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 M YLH + IHRDL + N+L+ + VK+ DFGL+K + Y + Sbjct 1115 MNYLHEKGIIHRDLKSMNILVKSVKVTKSEIGYVHVKVADFGLSKT-KDSSTRYSNQTWN 1173 Query 1062 DSPVFWYAPECLKEY---------------KFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 W APE + K+ SDV+SFG+ YE+LT Sbjct 1174 RGTNRWMAPEVINLGYESTEGEISFDGKVPKYPLKSDVYSFGMVCYEVLTGDVPFPE--- 1230 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + + ++ G R P CP E+ L+ +CW + RP+F + Sbjct 1231 -----------EKNPNNVKRMVLEGVRPDLPAHCPIELKALITDCWNQDPLKRPSFAVIC 1279 Query 1167 PILKTVH-------EKYQGQAPSV 1183 LK + YQ PS Sbjct 1280 QKLKYLKYLLMTGFSSYQDSYPST 1303 Score = 174 bits (440), Expect = 1e-42, Method: Composition-based stats. Identities = 58/370 (16%), Positives = 114/370 (31%), Gaps = 81/370 (22%) Query 562 IIMRGARASPRTLNLS----------QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 ++ R RA P + S SF + I LG G+ V + Sbjct 967 LLQRLKRAKPILPSFSSRPSWWNFYDDWSFSEKFFQWIQITGSLGSGSSATVEKAVWLG- 1025 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 V K + F +++++ H ++ Sbjct 1026 -------------------------TPVAKKTF---YGRNNEDFKREVEILAELCHPNIT 1057 Query 672 FVHGVCVRGPENI-----MVTEYVEHGPLDVWLRRE--------RGHVPMAWKMVVAQQL 718 + C ++ E ++ G L ++R + + + Q Sbjct 1058 SM--FC---SPLYRRKCSIIMELMD-GDLLALMQRRLDRNEDHDSPPFSILEVVDIILQT 1111 Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP--FIKLSDPGVGLGALSREERV--- 773 + ++YL K ++H ++ NIL+ + + + +K++D G+ S Sbjct 1112 SEGMNYLHEKGIIHRDLKSMNILVKSVKVTKSEIGYVHVKVADFGLSKTKDSSTRYSNQT 1171 Query 774 ---ERIPWLAPECLPGGAN-------------SLSTAMDKWGFGATLLEICFDGEAPLQS 817 W+APE + G D + FG E+ + Sbjct 1172 WNRGTNRWMAPEVINLGYESTEGEISFDGKVPKYPLKSDVYSFGMVCYEVLTGDVPFPEE 1231 Query 818 RSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 ++P+ + R LP +L L + C +P +RPSF I + L L+ + Sbjct 1232 KNPNNVKRMVLEGVRPDLPAHCPIELKALITDCWNQDPLKRPSFAVICQKLKYLKYLLMT 1291 Query 876 DVLTVNPDSP 885 + P Sbjct 1292 GFSSYQDSYP 1301 >sp|Q54QI2|Y9877_DICDI Serine/threonine-protein kinase DDB_G0283821 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0283821 PE=3 SV=1 Length=941 Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats. Identities = 74/284 (26%), Positives = 121/284 (43%), Gaps = 33/284 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G FGKV + N TG+ A+K + K + QEI +L+TL H +I+K Sbjct 19 VGKGAFGKV----FKALNAETGDFCAIKQIEKTIISEKQLPSIIQEIKLLQTLQHPNIVK 74 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020 + E + L +E++ GSL R+ L + Q+ +G+AYLH + I Sbjct 75 FIESYE--TSRYLYFALEFIEGGSLAKIAKRYGCFQEPLLSRYFSQVLKGLAYLHEKGVI 132 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF-- 1078 HRD+ + N+L+ + ++K+ DFG + FW APE ++ Sbjct 133 HRDIKSDNILITKEGVIKLADFGSCTY-----SAIDRKLTVVGTPFWMAPEVIQMDMNAR 187 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 A D+WS G TL E+LT +PP L + + Sbjct 188 STACDIWSLGCTLLEMLTG-----NPPYWDLGTMPAMFAMVNNPHPPIPNNI-------- 234 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIP---ILKTVHEKYQGQ 1179 ++ H + C+ + + RPT L+ I + +HE Q Q Sbjct 235 --SADLKHFLLACFVRDINKRPTASQLLEHPWIKQHIHEPSQSQ 276 Score = 187 bits (474), Expect = 4e-47, Method: Composition-based stats. Identities = 59/328 (18%), Positives = 101/328 (31%), Gaps = 39/328 (12%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + +G+G V++ G +K + Sbjct 9 SFSKYQIGEAVGKGAFGKVFKALNAETGDFC------------------------AIKQI 44 Query 645 DPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 + + + + L+ + H ++ E++E G L + + Sbjct 45 EKTIISEKQLPSIIQEIKLLQTLQHPNIVKFIESYETSRYLYFALEFIEGGSLAK-IAKR 103 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 G Q+ L+YL K ++H ++ NIL+ + G+ IKL+D G Sbjct 104 YGCFQEPLLSRYFSQVLKGLAYLHEKGVIHRDIKSDNILITKEGV-------IKLADFGS 156 Query 763 GL-GALSRE-ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR-- 818 A+ R+ V W+APE + N+ STA D W G TLLE+ G P Sbjct 157 CTYSAIDRKLTVVGTPFWMAPEVIQMDMNARSTACDIWSLGCTLLEML-TGNPPYWDLGT 215 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 P+ +P L C + +RP+ +L Q + Sbjct 216 MPAMFAMVNNPHPPIPNNISADLKHFLLACFVRDINKRPTASQLLEHPWIKQHIHEPSQS 275 Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEG 906 S I EG Sbjct 276 QPASSPEPSRIKSSGSGSKLSINTYAEG 303 >sp|Q8RXC8|RBK2_ARATH Receptor-like cytosolic serine/threonine-protein kinase RBK2 OS=Arabidopsis thaliana OX=3702 GN=RBK2 PE=1 SV=1 Length=460 Score = 214 bits (545), Expect = 4e-59, Method: Composition-based stats. Identities = 70/336 (21%), Positives = 133/336 (40%), Gaps = 23/336 (7%) Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD-- 902 + ++ P + I ++ + N + + + + Sbjct 86 MKRLSSFPPLSGAAPPIIKQNKSADPNMNGMVLHDIYDFQSSLQNFSISDIEIATDNFSP 145 Query 903 ---LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHI 959 +G G + V G+++AVK L + + + E+ I+ + H + Sbjct 146 ENIIGRGGYADVYQGILPE-----GKLIAVKRLTKGTPDEQTAEFLSELGIIAHVDHPNT 200 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICEGMAYLHA 1016 K+ GCC + G + LV PLGSL L ++ + ++ A +G+ YLH Sbjct 201 AKFIGCCIEGG---MHLVFRLSPLGSLGSLLHGPSKYKLTWSRRYNVALGTADGLVYLHE 257 Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + IHRD+ A N+LL D +I DFGLAK +P+ ++ V + + ++APE Sbjct 258 GCQRRIIHRDIKADNILLTEDFQPQICDFGLAKWLPKQLTHHNVSK-FEGTFGYFAPEYF 316 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 +DV++FGV L EL+T + L+ A+ + + EL++ Sbjct 317 MHGIVDEKTDVFAFGVLLLELITGHPALD---ESQQSLVLWAKPLLERKAIKELVDPSLG 373 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 + + C + + RP ++ +L Sbjct 374 DEYNREELIRLTSTASLCIDQSSLLRPRMSQVVELL 409 Score = 174 bits (441), Expect = 2e-45, Method: Composition-based stats. Identities = 50/297 (17%), Positives = 93/297 (31%), Gaps = 50/297 (17%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 N +++ +L +S + + + +G+G +VY+G L Sbjct 112 NMNGMVLHDIYDFQSSLQNFSISDIEIATDNFSPENIIGRGGYADVYQGILPEGK----- 166 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL-AFYETASLMSQVSHTHLAFVHGV 676 + +K L D F +++ V H + A G Sbjct 167 --------------------LIAVKRLTKGTPDEQTAEFLSELGIIAHVDHPNTAKFIGC 206 Query 677 CVRGPENIMVTEYVEHGPLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVH 732 C+ G +V G L L + + + VA A L YL + ++H Sbjct 207 CIEGG-MHLVFRLSPLGSLGSLLHGPSKYKLTWSRRYNVALGTADGLVYLHEGCQRRIIH 265 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVG------LGALSREERVERIPWLAPECLPG 786 ++ NILL + + D G+ L + + + APE Sbjct 266 RDIKADNILLTEDFQPQ-------ICDFGLAKWLPKQLTHHNVSKFEGTFGYFAPEYFMH 318 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT 843 G + D + FG LLE+ + S++ + L + +L Sbjct 319 GI--VDEKTDVFAFGVLLLELITG----HPALDESQQSLVLWAKPLLERKAIKELVD 369 >sp|Q9SYQ8|CLV1_ARATH Receptor protein kinase CLAVATA1 OS=Arabidopsis thaliana OX=3702 GN=CLV1 PE=1 SV=3 Length=980 Score = 224 bits (572), Expect = 4e-59, Method: Composition-based stats. Identities = 75/327 (23%), Positives = 126/327 (39%), Gaps = 29/327 (9%) Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920 ++ + + + + + LK+ +G+G G V + Sbjct 656 SVAIRQMNKKKNQKSLAWKLTAFQKLDFKSEDVLECLKEENIIGKGGAGIVYRG-----S 710 Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 VA+K L + G+ EI L + H HI++ G ++ L+ EY Sbjct 711 MPNNVDVAIKRLVGRGTGRSDHGFTAEIQTLGRIRHRHIVRLLGYVANKDTN--LLLYEY 768 Query 981 VPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDND 1034 +P GSL + L + A + +G+ YLH +HRD+ + N+LLD+D Sbjct 769 MPNGSLGELLHGSKGGHLQWETRHRVAVEAAKGLCYLHHDCSPLILHRDVKSNNILLDSD 828 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 + DFGLAK + +G + S + APE K SDV+SFGV L EL Sbjct 829 FEAHVADFGLAKFLVDGAASECMSSIAGS-YGYIAPEYAYTLKVDEKSDVYSFGVVLLEL 887 Query 1095 LTHCDSSQSPPTKFLELIGIAQGQMTVLR----------LTELLERGERLPRPDKCPCEV 1144 + P +F E + I + + +++ P V Sbjct 888 IAGK----KPVGEFGEGVDIVRWVRNTEEEITQPSDAAIVVAIVDPRLTG-YPLTSVIHV 942 Query 1145 YHLMKNCWETEASFRPTFENLIPILKT 1171 + + C E EA+ RPT ++ +L Sbjct 943 FKIAMMCVEEEAAARPTMREVVHMLTN 969 Score = 185 bits (470), Expect = 1e-46, Method: Composition-based stats. Identities = 58/323 (18%), Positives = 104/323 (32%), Gaps = 67/323 (21%) Query 576 LSQLSFHRVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 +L F D E + + + +G+G VY G Sbjct 678 FQKLDFKSEDVLECLKEENIIGKGGAGIVYRG-------------------------SMP 712 Query 635 QELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + V +K L F + ++ H H+ + G N+++ EY+ +G Sbjct 713 NNVDVAIKRLVGRGTGRSDHGFTAEIQTLGRIRHRHIVRLLGYVANKDTNLLLYEYMPNG 772 Query 694 PLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAE 749 L L + GH+ + VA + A L YL + ++H +V NILL A Sbjct 773 SLGELLHGSKGGHLQWETRHRVAVEAAKGLCYLHHDCSPLILHRDVKSNNILLDSDFEAH 832 Query 750 GTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 ++D G+ + ++APE + D + FG Sbjct 833 -------VADFGLAKFLVDGAASECMSSIAGSYGYIAPEYA--YTLKVDEKSDVYSFGVV 883 Query 804 LLEICFDGEA---------PLQSRSPSEKE------------HFYQRQHRLPEPSCPQLA 842 LLE+ + ++ +E+E R P S + Sbjct 884 LLELIAGKKPVGEFGEGVDIVRWVRNTEEEITQPSDAAIVVAIVDPRLTGYPLTSVIHVF 943 Query 843 TLTSQCLTYEPTQRPSFRTILRD 865 + C+ E RP+ R ++ Sbjct 944 KIAMMCVEEEAAARPTMREVVHM 966 >sp|Q9TXJ0|CMK1_CAEEL Calcium/calmodulin-dependent protein kinase type 1 OS=Caenorhabditis elegans OX=6239 GN=cmk-1 PE=1 SV=1 Length=348 Score = 211 bits (536), Expect = 4e-59, Method: Composition-based stats. Identities = 65/265 (25%), Positives = 100/265 (38%), Gaps = 34/265 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G F KV L G+M AVK + + EI +LR L H +I++ Sbjct 28 LGTGAFSKVFLAESK---SDAGQMYAVKCIDKKALKGKEESLENEIKVLRKLRHNNIVQL 84 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 +++ + + LVME V G L D + + S +Q+ E + ++H +H Sbjct 85 FDTYDEK--QFVYLVMELVTGGELFDRIVAKGSYTEQDASNLIRQVLEAVGFMHDNGVVH 142 Query 1022 RDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 RDL N+L D D + I DFGL+K G V + APE L++ + Sbjct 143 RDLKPENLLYYNQDEDSKIMISDFGLSKTEDSG-----VMATACGTPGYVAPEVLQQKPY 197 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP- 1137 A DVWS GV Y LL + ++++ P Sbjct 198 GKAVDVWSIGVIAYILLCGYPPF--------------YDESDANLFAQIIKGEYEFDAPY 243 Query 1138 -DKCPCEVYHLM--KNCWETEASFR 1159 D+ + C + R Sbjct 244 WDQISDSAKDFITHLMCC--DPEAR 266 Score = 154 bits (390), Expect = 1e-39, Method: Composition-based stats. Identities = 43/308 (14%), Positives = 90/308 (29%), Gaps = 35/308 (11%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 +++ LG G + V+ + + +K +D Sbjct 19 REKYDFRDVLGTGAFSKVFLAESKSDAGQMY-----------------------AVKCID 55 Query 646 PSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 ++ ++ H ++ + +V E V G L + +G Sbjct 56 KKALKGKEESLENEIKVLRKLRHNNIVQLFDTYDEKQFVYLVMELVTGGELFDRI-VAKG 114 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + +Q+ A+ ++ + +VH ++ N+L + I +SD G+ Sbjct 115 SYTEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLL----YYNQDEDSKIMISDFGLSK 170 Query 765 GALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 S ++APE L A+D W G I G P S + Sbjct 171 TEDSGVMATACGTPGYVAPEVLQQ--KPYGKAVDVWSIGVIAY-ILLCGYPPFYDESDAN 227 Query 823 KEHFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 + + P Q++ +T+ P R +D + T + Sbjct 228 LFAQIIKGEYEFDAPYWDQISDSAKDFITHLMCCDPEARFTCQDALSHPWISGNTAYTHD 287 Query 882 PDSPASDP 889 + Sbjct 288 IHGTVAVH 295 >sp|Q9LUL4|SRF7_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 7 OS=Arabidopsis thaliana OX=3702 GN=SRF7 PE=1 SV=1 Length=717 Score = 221 bits (562), Expect = 4e-59, Method: Composition-based stats. Identities = 80/344 (23%), Positives = 139/344 (40%), Gaps = 25/344 (7%) Query 834 PEPSCPQLATLTSQCLTYEPTQRP--SFRTILRDLTRLQPHNLADVLTVNPDSPASDPTV 891 P +L T S L P++R + A V+ N ++ Sbjct 354 PLVETKKLDTSLSMNLRPPPSERHKSFDDDDSTMRKPIVAKKAAVVVPSNVNTYTVSDLQ 413 Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEI-DI 950 LGEG FG+V ++ G+++AVK + + P + EI Sbjct 414 VATNSFSVDNLLGEGTFGRVYRAQFE-----DGKVLAVKKIDSSALPTDTADDFTEIVSK 468 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQ 1005 + L HE++ K G C + G+ +V E+ GSL D+L + + A Sbjct 469 IAHLDHENVTKLDGYCSEHGQH--LVVYEFHRNGSLHDFLHLAEEESKPLIWNPRVKIAL 526 Query 1006 QICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD 1062 + YLH + +H+++ + N+LLD++ + D GLA +P +E ++G Sbjct 527 GTARALEYLHEVCSPSIVHKNIKSANILLDSELNPHLSDSGLASFLPTANELLNQNDEG- 585 Query 1063 SPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQM-T 1120 + APE ++ SDV+SFGV + ELLT S ++ L+ A Q+ Sbjct 586 ----YSAPETSMSGQYSLKSDVYSFGVVMLELLTGRKPFDSTRSRSEQSLVRWATPQLHD 641 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + L ++++ + P K ++ C + E FRP Sbjct 642 IDALGKMVDPALKGLYPVKSLSRFADVIALCVQPEPEFRPPMSE 685 Score = 184 bits (468), Expect = 4e-47, Method: Composition-based stats. Identities = 71/325 (22%), Positives = 118/325 (36%), Gaps = 62/325 (19%) Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 + A P +N +S +V + + LG+GT VY + Sbjct 395 KAAVVVPSNVNTYTVSDLQVATNSFSVDNLLGEGTFGRVYRAQFEDGKVL---------- 444 Query 625 DPLVPGRDRGQELRVVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE 682 +K +D S D A F E S ++ + H ++ + G C + Sbjct 445 ---------------AVKKIDSSALPTDTADDFTEIVSKIAHLDHENVTKLDGYCSEHGQ 489 Query 683 NIMVTEYVEHGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVC 736 +++V E+ +G L +L E P+ W ++ +A A AL YL + ++VH N+ Sbjct 490 HLVVYEFHRNGSLHDFLHLAEEESKPLIWNPRVKIALGTARALEYLHEVCSPSIVHKNIK 549 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVER--IPWLAPECLPGGANSLSTA 794 NILL LSD G+ + E + + + APE G S Sbjct 550 SANILLDSELNPH-------LSDSGLASFLPTANELLNQNDEGYSAPETSMSG--QYSLK 600 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL------------------PEP 836 D + FG +LE+ + +RS SE+ +L P Sbjct 601 SDVYSFGVVMLELLTGRKPFDSTRSRSEQSLVRWATPQLHDIDALGKMVDPALKGLYPVK 660 Query 837 SCPQLATLTSQCLTYEPTQRPSFRT 861 S + A + + C+ EP RP Sbjct 661 SLSRFADVIALCVQPEPEFRPPMSE 685 >sp|Q658G7|SIK1_ORYSJ LRR receptor-like serine/threonine-protein kinase SIK1 OS=Oryza sativa subsp. japonica OX=39947 GN=SIK1 PE=1 SV=1 Length=980 Score = 224 bits (572), Expect = 4e-59, Method: Composition-based stats. Identities = 74/358 (21%), Positives = 131/358 (37%), Gaps = 24/358 (7%) Query 838 CPQLATLTSQC--LTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895 C L + C L + +Q VL ++ + + Sbjct 592 CIILGFIILLCVLLLAIYKTNQPQPLVKGSDKPVQGPPKLVVLQMDMAIHTYEDIMRLTE 651 Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 L + +G G V +G+ +AVK L + R ++ E++ + ++ Sbjct 652 NLSEKYIIGYGASSTVYKCELK-----SGKAIAVKRLYSQYNHSLRE-FETELETIGSIR 705 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGM 1011 H +++ G L +Y+ GSL D L + + L A +G+ Sbjct 706 HRNLVSLHGFSLSPHGN--LLFYDYMENGSLWDLLHGPSKKVKLNWDTRLRIAVGAAQGL 763 Query 1012 AYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 AYLH IHRD+ + N+LLD + + DFG+AK VP + G + + Sbjct 764 AYLHHDCNPRIIHRDVKSSNILLDENFEAHLSDFGIAKCVPSAKSHASTYVLG--TIGYI 821 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE + + SDV+SFG+ L ELLT + + ++ A + E + Sbjct 822 DPEYARTSRLNEKSDVYSFGIVLLELLTGKKAVDNESNLHQLILSKADDNT----VMEAV 877 Query 1129 ERGERLPRPD-KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS 1185 + + D + + L C + S RPT + +L ++ P Sbjct 878 DSEVSVTCTDMGLVRKAFQLALLCTKRHPSDRPTMHEVARVLLSLLPASAMTTPKTVD 935 Score = 188 bits (477), Expect = 2e-47, Method: Composition-based stats. Identities = 54/300 (18%), Positives = 104/300 (35%), Gaps = 57/300 (19%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + +++ +G G + VY+ L+ + +K L Sbjct 650 TENLSEKYIIGYGASSTVYKCELKSGK-------------------------AIAVKRLY 684 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 ++ F + + H +L +HG + N++ +Y+E+G L L Sbjct 685 SQYNHSLREFETELETIGSIRHRNLVSLHGFSLSPHGNLLFYDYMENGSLWDLLHGPSKK 744 Query 706 VPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 V + W ++ +A A L+YL N ++H +V NILL + LSD Sbjct 745 VKLNWDTRLRIAVGAAQGLAYLHHDCNPRIIHRDVKSSNILLDE-------NFEAHLSDF 797 Query 761 GVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ S + I ++ PE + L+ D + FG LLE+ +A Sbjct 798 GIAKCVPSAKSHASTYVLGTIGYIDPEYART--SRLNEKSDVYSFGIVLLELLTGKKAVD 855 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLA-------------TLTSQCLTYEPTQRPSFRTI 862 + + + + E +++ L C P+ RP+ + Sbjct 856 NESNLHQLILSKADDNTVMEAVDSEVSVTCTDMGLVRKAFQLALLCTKRHPSDRPTMHEV 915 >sp|Q39191|WAK1_ARATH Wall-associated receptor kinase 1 OS=Arabidopsis thaliana OX=3702 GN=WAK1 PE=1 SV=2 Length=735 Score = 221 bits (563), Expect = 4e-59, Method: Composition-based stats. Identities = 71/279 (25%), Positives = 112/279 (40%), Gaps = 18/279 (6%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG+G G V +VA+K + Q + E+ +L + H +++K Sbjct 415 LGQGGQGTVYKGIL-----PDNSIVAIKKARLGDSSQ-VEQFINEVLVLSQINHRNVVKL 468 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEGMAYLHAQ- 1017 GCC + E L LV E++ G+L D+L S+ L A ++ +AYLH+ Sbjct 469 LGCCLE-TEVPL-LVYEFITNGTLFDHLHGSMIDSSLTWEHRLKIAIEVAGTLAYLHSSA 526 Query 1018 --HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 IHRD+ N+LLD + K+ DFG ++ +P E G + + PE Sbjct 527 SIPIIHRDIKTANILLDVNLTAKVADFGASRLIPMDKEELETMVQG--TLGYLDPEYYNT 584 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 SDV+SFGV L ELL+ + P L+ RL E++ Sbjct 585 GLLNEKSDVYSFGVVLMELLSGQKALCFKRPQSSKHLVSYFATATKENRLDEIIGGEVMN 644 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 K E + C RP + + L+ + Sbjct 645 EDNLKEIQEAARIAAECTRLMGEERPRMKEVAAKLEALR 683 Score = 207 bits (526), Expect = 2e-54, Method: Composition-based stats. Identities = 79/484 (16%), Positives = 151/484 (31%), Gaps = 80/484 (17%) Query 468 DGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLR--KFPIEQQDGAFVLEGW-----G 520 DG + + ++ R + F + Q G + L+ Sbjct 271 DGNPYLSAGCQDVNECTTSSTIHRHNCSDPKTCRNKVGGFYCKCQSG-YRLDTTTMSCKR 329 Query 521 RSFPSVRELGAALQGCLL-RAGDDCFSLRRCCLPQPG--------ETSNLIIMRGARASP 571 + F L G L+ G C R L ++ R + A P Sbjct 330 KEFAWTTILLVTTIGFLVILLGVACIQQRMKHLKDTKLREQFFEQNGGGMLTQRLSGAGP 389 Query 572 RTLNLSQLSFHRVD--QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 +++ + + + LGQG + VY+G L Sbjct 390 SNVDVKIFTEDGMKKATNGYAESRILGQGGQGTVYKGILPDNSI---------------- 433 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 V +K F ++SQ++H ++ + G C+ ++V E+ Sbjct 434 ---------VAIKKARLGDSSQVEQFINEVLVLSQINHRNVVKLLGCCLETEVPLLVYEF 484 Query 690 VEHGPLDVWLRRERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLAR 744 + +G L L + W ++ +A ++A L+YL + ++H ++ NILL Sbjct 485 ITNGTLFDHLHGSMIDSSLTWEHRLKIAIEVAGTLAYLHSSASIPIIHRDIKTANILLD- 543 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWG 799 + K++D G +E + + +L PE G L+ D + Sbjct 544 ------VNLTAKVADFGASRLIPMDKEELETMVQGTLGYLDPEYYNTGL--LNEKSDVYS 595 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQ-----RQHRLPEPS------------CPQLA 842 FG L+E+ +A R S K +++RL E + A Sbjct 596 FGVVLMELLSGQKALCFKRPQSSKHLVSYFATATKENRLDEIIGGEVMNEDNLKEIQEAA 655 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902 + ++C +RP + + L L+ + H + Sbjct 656 RIAAECTRLMGEERPRMKEVAAKLEALRVEKTKHKWSDQYPEENEHLIGGHILSAQGETS 715 Query 903 LGEG 906 G Sbjct 716 SSIG 719 >sp|P06245|KAPB_YEAST cAMP-dependent protein kinase type 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TPK2 PE=1 SV=2 Length=380 Score = 211 bits (538), Expect = 4e-59, Method: Composition-based stats. Identities = 75/346 (22%), Positives = 128/346 (37%), Gaps = 48/346 (14%) Query 857 PSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCY 916 P R + Q + + + P + + +R LG G FG+V L Sbjct 30 PHHDLQQRQQQQQQRQHQQLLTSQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLV-- 87 Query 917 DPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL 974 + G A+K LK + E +L+ + H +I+ G +D +++ Sbjct 88 --RSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDA--RNI 143 Query 975 QLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDN 1033 +VM+Y+ G L L + +A ++ + YLHA + I+RDL N+LLD Sbjct 144 FMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDR 203 Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 + +KI DFG AK E V + APE + + + D WS GV +YE Sbjct 204 NGHIKITDFGFAK------EVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYE 257 Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 +L T ++ E + +G ++ P +V L+ Sbjct 258 MLAGYTPFYDT---------------TPMKTYEKILQG-KVVYPPYFHPDVVDLLSKLIT 301 Query 1154 TEASFR--------------PTFENLI-PIL--KTVHEKYQGQAPS 1182 + + R P F ++ L K + Y+ S Sbjct 302 ADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITS 347 Score = 172 bits (437), Expect = 1e-45, Method: Composition-based stats. Identities = 55/285 (19%), Positives = 107/285 (38%), Gaps = 34/285 (12%) Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 + + S +S + + + LG G+ V+ +R +G K+ Sbjct 51 TSQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVH--LVRSVHNGRYYAIKVLK------ 102 Query 630 GRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEY 689 ++ V +K ++ ++ + ++ V H L + G MV +Y Sbjct 103 -----KQQVVKMKQVEHTNDERR--------MLKLVEHPFLIRMWGTFQDARNIFMVMDY 149 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 +E G L LR+ + P A ++ AL YL N+++ ++ NILL R G Sbjct 150 IEGGELFSLLRKSQ-RFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNG--- 205 Query 750 GTSPFIKLSDPGVGLGALSRE-ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 IK++D G + ++APE + + ++D W G + E+ Sbjct 206 ----HIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITT--KPYNKSVDWWSLGVLIYEML 259 Query 809 FDGEAPLQSRSPSEKEHFYQRQHRL-PEPSCPQLATLTSQCLTYE 852 G P +P + + + P P + L S+ +T + Sbjct 260 A-GYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITAD 303 >sp|Q95ZQ4|AAPK2_CAEEL 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Caenorhabditis elegans OX=6239 GN=aak-2 PE=1 SV=2 Length=626 Score = 218 bits (556), Expect = 4e-59, Method: Composition-based stats. Identities = 82/291 (28%), Positives = 120/291 (41%), Gaps = 35/291 (12%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRT 953 + LG G FGKV + ++ T VAVK L ++EI L Sbjct 86 HYILKETLGVGTFGKVKVGIHE----TTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSL 141 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMA 1012 H HII+ + + ++ME+V G L DY+ +H + A+ F QQI G+ Sbjct 142 FRHPHIIRLYQVISTPSD--IFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVD 199 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 Y H +HRDL N+LLD VKI DFGL+ + +G +R SP + APE Sbjct 200 YCHRHMVVHRDLKPENLLLDEQNNVKIADFGLSNIMTDGD---FLRTSCGSPN-YAAPEV 255 Query 1073 LKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + + DVWS GV LY LL V L ++ G Sbjct 256 ISGKLYAGPEVDVWSCGVILYALLCGTLPFDDEH---------------VPSLFRKIKSG 300 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182 P PD + +L+ + + R T +++I HE +Q P+ Sbjct 301 V-FPTPDFLERPIVNLLHHMLCVDPMKRATIKDVIA-----HEWFQKDLPN 345 Score = 175 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 53/317 (17%), Positives = 97/317 (31%), Gaps = 40/317 (13%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 T N M T +L ++ LG GT V Sbjct 57 TDNSSKMSSPGGETSTKQQQELK-AQIKIGHYILKETLGVGTFGKV-------------- 101 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVH 674 G + +V +K+L+ D+ +S H H+ ++ Sbjct 102 ----------KVGIHETTQYKVAVKILNRQKIKSLDVVGKIRREIQNLSLFRHPHIIRLY 151 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGN 734 V + M+ E+V G L ++ + G + A QQ+ S + Y +VH + Sbjct 152 QVISTPSDIFMIMEHVSGGELFDYIVKH-GRLKTAEARRFFQQIISGVDYCHRHMVVHRD 210 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSL 791 + N+LL +K++D G+ + + APE + G + Sbjct 211 LKPENLLLDEQN-------NVKIADFGLSNIMTDGDFLRTSCGSPNYAAPEVISGKLYA- 262 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTY 851 +D W G L + PS P+ + L L Sbjct 263 GPEVDVWSCGVILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHMLCV 322 Query 852 EPTQRPSFRTILRDLTR 868 +P +R + + ++ Sbjct 323 DPMKRATIKDVIAHEWF 339 >sp|Q6ERS0|CIPKR_ORYSJ Putative CBL-interacting protein kinase 27 OS=Oryza sativa subsp. japonica OX=39947 GN=CIPK27 PE=3 SV=1 Length=404 Score = 212 bits (540), Expect = 4e-59, Method: Composition-based stats. Identities = 63/270 (23%), Positives = 110/270 (41%), Gaps = 27/270 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ--HRSGWKQEIDILRTLYHEHII 960 LG G+FG+V + + TG VA+K + D + K+EI +++ + H ++ Sbjct 17 LGHGNFGRV----HAARDVRTGRAVAMKVVSKDKVERAGMAEQIKREIAVMKMVSHPSVV 72 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHY 1019 + + + + L +E V G L D + RH +G + +Q+ + + H + Sbjct 73 ELHEVMATRTK--VYLALELVRGGELFDRIARHGRVGEGVARRYFRQLVSAVDFCHGRGV 130 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 HRDL N+LLD +K+ DFGL+ + +P + APE L + Sbjct 131 YHRDLKPENLLLDEAGNLKVADFGLSALACHARPDGLLHTACGTPA-YVAPEVLAGNGYD 189 Query 1080 -YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 +D+WS GV LY LL Q ++ + + RG+ P Sbjct 190 GAKADLWSCGVILYVLLAGALPFQDD---------------NLVCMYRKMRRGD-FCCPP 233 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 + L+K+ + R T L+ Sbjct 234 WVTTDARKLIKSLLDPNPGTRITVAGLLET 263 Score = 157 bits (397), Expect = 4e-40, Method: Composition-based stats. Identities = 57/278 (21%), Positives = 88/278 (32%), Gaps = 52/278 (19%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 LG G V+ RD V +KV+ Sbjct 12 EMGRVLGHGNFGRVH------------------------AARDVRTGRAVAMKVVSKDKV 47 Query 650 D---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 + +A ++M VSH + +H V + + E V G L + R G V Sbjct 48 ERAGMAEQIKREIAVMKMVSHPSVVELHEVMATRTKVYLALELVRGGELFDRIARH-GRV 106 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV-GLG 765 +QL SA+ + + + H ++ N+LL G +K++D G+ L Sbjct 107 GEGVARRYFRQLVSAVDFCHGRGVYHRDLKPENLLLDEAG-------NLKVADFGLSALA 159 Query 766 ALSR-----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 +R ++APE L G D W G L + G P Q Sbjct 160 CHARPDGLLHTACGTPAYVAPEVLAGNGYD-GAKADLWSCGVILY-VLLAGALPFQD--- 214 Query 821 SEKEHFYQRQHRLPEPSCPQLAT-----LTSQCLTYEP 853 + R+ R + CP T L L P Sbjct 215 -DNLVCMYRKMRRGDFCCPPWVTTDARKLIKSLLDPNP 251 >sp|F4I2N7|RLK7_ARATH Receptor-like protein kinase 7 OS=Arabidopsis thaliana OX=3702 GN=RLK7 PE=1 SV=1 Length=977 Score = 224 bits (572), Expect = 4e-59, Method: Composition-based stats. Identities = 67/318 (21%), Positives = 122/318 (38%), Gaps = 28/318 (9%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA 934 + ++ S +K+ +G G G V G G+ VAVK ++ Sbjct 644 HESWSIKSFRKMSFTEDDIIDSIKEENLIGRGGCGDVYRVVL-----GDGKEVAVKHIRC 698 Query 935 DCGPQH--------------RSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 ++ ++ E+ L ++ H +++K C + S LV EY Sbjct 699 SSTQKNFSSAMPILTEREGRSKEFETEVQTLSSIRHLNVVKLY--CSITSDDSSLLVYEY 756 Query 981 VPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDND 1034 +P GSL D L + ++G A +G+ YLH + IHRD+ + N+LLD Sbjct 757 LPNGSLWDMLHSCKKSNLGWETRYDIALGAAKGLEYLHHGYERPVIHRDVKSSNILLDEF 816 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP-ECLKEYKFYYASDVWSFGVTLYE 1093 +I DFGLAK + + + AP E K DV+SFGV L E Sbjct 817 LKPRIADFGLAKILQASNGGPESTHVVAGTYGYIAPAEYGYASKVTEKCDVYSFGVVLME 876 Query 1094 LLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 L+T ++ + +++ + + + + ++ + C Sbjct 877 LVTGKKPIEAEFGESKDIVNWVSNNLKSKESVMEIVDKKIGEMYREDAVKMLRIAIICTA 936 Query 1154 TEASFRPTFENLIPILKT 1171 RPT +++ +++ Sbjct 937 RLPGLRPTMRSVVQMIED 954 Score = 182 bits (462), Expect = 2e-45, Method: Composition-based stats. Identities = 48/272 (18%), Positives = 101/272 (37%), Gaps = 33/272 (12%) Query 575 NLSQLSFHRVDQKE-ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 + ++SF D + I + + +G+G +VY L + + Sbjct 651 SFRKMSFTEDDIIDSIKEENLIGRGGCGDVYRVVLGDGKEVAVKHIRCSSTQKNFSS--- 707 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + +L + F +S + H ++ ++ +++V EY+ +G Sbjct 708 ------AMPILTEREG-RSKEFETEVQTLSSIRHLNVVKLYCSITSDDSSLLVYEYLPNG 760 Query 694 PLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAE 749 L L ++ ++ + +A A L YL + ++H +V NILL Sbjct 761 SLWDMLHSCKKSNLGWETRYDIALGAAKGLEYLHHGYERPVIHRDVKSSNILLDEFLKP- 819 Query 750 GTSPFIKLSDPGVGL-------GALSREERVERIPWLAP-ECLPGGANSLSTAMDKWGFG 801 +++D G+ G S ++AP E G A+ ++ D + FG Sbjct 820 ------RIADFGLAKILQASNGGPESTHVVAGTYGYIAPAEY--GYASKVTEKCDVYSFG 871 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833 L+E+ G+ P+++ K+ + L Sbjct 872 VVLMELV-TGKKPIEAEFGESKDIVNWVSNNL 902 >sp|Q94CU5|NEK5_ORYSJ Serine/threonine-protein kinase Nek5 OS=Oryza sativa subsp. japonica OX=39947 GN=NEK5 PE=2 SV=1 Length=943 Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats. Identities = 63/294 (21%), Positives = 120/294 (41%), Gaps = 30/294 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEI 948 + + +G G FG L + +K ++ A + R QE+ Sbjct 1 MDSRMDQYEVMEQIGRGAFGAAILVNHKTEKK----KYVLKKIRLARQTERCRKSAHQEM 56 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQ 1005 ++ L H +I+++K ++G + +V Y G + + + + + +LL + Sbjct 57 ALIARLQHPYIVEFKEAWVEKG-CYVCIVTGYCEGGDMAELMKKANGTYFPEEKLLKWFA 115 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 Q+ + YLH+ +HRDL N+ L D+ +++GDFGLAK + + Sbjct 116 QLALAVDYLHSNFVLHRDLKCSNIFLTKDQDIRLGDFGLAKTLKADD----LTSSVVGTP 171 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 + PE L + + + SD+WS G +YE+ ++ P K ++ G L Sbjct 172 NYMCPELLADIPYGFKSDIWSLGCCMYEM-----AAHRPAFKAFDMAG----------LI 216 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQ 1177 + R P P + L+K+ RPT ++ P L+ +Y+ Sbjct 217 SKINRSSIGPLPPCYSPSMKSLIKSMLRKSPEHRPTASEILKSPYLQPYVNQYR 270 Score = 151 bits (382), Expect = 6e-36, Method: Composition-based stats. Identities = 53/311 (17%), Positives = 101/311 (32%), Gaps = 41/311 (13%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 R+DQ E+ + +G+G ++ ++ V+ K Sbjct 4 RMDQYEV--MEQIGRGAFG-----------------------AAILVNHKTEKKKYVLKK 38 Query 643 -VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLR 700 L + ++ +L++++ H ++ V +VT Y E G + ++ Sbjct 39 IRLARQTERCRKSAHQEMALIARLQHPYIVEFKEAWVEKGCYVCIVTGYCEGGDMAELMK 98 Query 701 RERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + G + P + QLA A+ YL + ++H ++ NI L + I+L D Sbjct 99 KANGTYFPEEKLLKWFAQLALAVDYLHSNFVLHRDLKCSNIFLTK-------DQDIRLGD 151 Query 760 PGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL- 815 G+ + + V ++ PE L D W G + E+ A Sbjct 152 FGLAKTLKADDLTSSVVGTPNYMCPELLADIPYGF--KSDIWSLGCCMYEMAAHRPAFKA 209 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + + LP P + +L L P RP+ IL+ N Sbjct 210 FDMAGLISKINRSSIGPLPPCYSPSMKSLIKSMLRKSPEHRPTASEILKSPYLQPYVNQY 269 Query 876 DVLTVNPDSPA 886 Sbjct 270 RPFADISHPIH 280 >sp|Q9M0T3|MP3K3_ARATH Mitogen-activated protein kinase kinase kinase 3 OS=Arabidopsis thaliana OX=3702 GN=MEKK3 PE=2 SV=1 Length=560 Score = 217 bits (552), Expect = 4e-59, Method: Composition-based stats. Identities = 78/333 (23%), Positives = 125/333 (38%), Gaps = 38/333 (11%) Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD--- 902 S C P+ R R + V F K Sbjct 248 STCSLMTPSMEFPDRISFRKRDFSEEGPSGRVKEKRKLMRNKLIENFRKPEDITSWLKGQ 307 Query 903 -LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKA-DCGPQHRSGWKQ---EIDILRTLYHE 957 LG G + V G+ AVK + D G Q + +Q EI +L L H+ Sbjct 308 LLGRGSYASVYEAI-----SEDGDFFAVKEVSLLDKGIQAQECIQQLEGEIALLSQLQHQ 362 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ 1017 +I++Y+G + L + +E V GS++ R+ + + L+ +QI G+ YLH + Sbjct 363 NIVRYRG--TAKDVSKLYIFLELVTQGSVQKLYERYQLSYTVVSLYTRQILAGLNYLHDK 420 Query 1018 HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 ++HRD+ N+L+D + VK+ DFGLA+A +FW APE + Sbjct 421 GFVHRDIKCANMLVDANGTVKLADFGLAEASKFNDI-----MSCKGTLFWMAPEVINRKD 475 Query 1078 FY---YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 +D+WS G T+ E+ T I + ++ + RG Sbjct 476 SDGNGSPADIWSLGCTVLEMCTG---------------QIPYSDLKPIQAAFKIGRGTLP 520 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 PD + H + C + RPT L+ Sbjct 521 DVPDTLSLDARHFILTCLKVNPEERPTAAELLH 553 Score = 179 bits (454), Expect = 3e-46, Method: Composition-based stats. Identities = 76/424 (18%), Positives = 142/424 (33%), Gaps = 56/424 (13%) Query 472 LIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKF-----------PIEQQDGAFVLEGWG 520 L+ S P R+ S+ RK P + + L+G Sbjct 167 LMTPSLEFPDRISFRKKDFSEKGPSRHVWEKRKLTRAKLIENFCNPEDIEPVTSWLKGQL 226 Query 521 RSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETS------NLIIMRGARASPRTL 574 S + A+ + + C SL + P S + G R L Sbjct 227 LGEESFASVYEAISDSSVGSESTC-SLMTPSMEFPDRISFRKRDFSEEGPSGRVKEKRKL 285 Query 575 NLSQLSFHRVDQKEIT---QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 ++L + ++IT + LG+G+ +VYE +E + D+ Sbjct 286 MRNKLIENFRKPEDITSWLKGQLLGRGSYASVYEAISEDGDFFAVKEVSLLDKGIQA--- 342 Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 + +L+SQ+ H ++ G + + E V Sbjct 343 -----------------QECIQQLEGEIALLSQLQHQNIVRYRGTAKDVSKLYIFLELVT 385 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 G + ER + + +Q+ + L+YL +K VH ++ N+L+ Sbjct 386 QGSVQKL--YERYQLSYTVVSLYTRQILAGLNYLHDKGFVHRDIKCANMLVD-------A 436 Query 752 SPFIKLSDPGVGLGALSRE--ERVERIPWLAPECL-PGGANSLSTAMDKWGFGATLLEIC 808 + +KL+D G+ + + + W+APE + ++ + D W G T+LE+C Sbjct 437 NGTVKLADFGLAEASKFNDIMSCKGTLFWMAPEVINRKDSDGNGSPADIWSLGCTVLEMC 496 Query 809 FDGEAPLQSRSPSEKEHFYQRQ--HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 G+ P P + R +P+ CL P +RP+ +L Sbjct 497 -TGQIPYSDLKPIQAAFKIGRGTLPDVPDTLSLDARHFILTCLKVNPEERPTAAELLHHP 555 Query 867 TRLQ 870 + Sbjct 556 FVIN 559 >sp|Q7RZD3|STE20_NEUCR Serine/threonine-protein kinase ste20 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=stk-4 PE=3 SV=1 Length=954 Score = 224 bits (571), Expect = 5e-59, Method: Composition-based stats. Identities = 57/274 (21%), Positives = 114/274 (42%), Gaps = 23/274 (8%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 + + +G+G G V G+ +VA+K + + P+ + EI +++ Sbjct 670 PREIYRGFTKIGQGASGGVYTGH----ERGSNRLVAIKQMNLEQQPK-KDLIINEILVMK 724 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 H +I+ + GE L +VMEY+ GSL D + + + Q+ ++ G+ Sbjct 725 ESSHPNIVNFIDSYLCAGE--LWVVMEYMEGGSLTDVVTFNIMTEGQIASVCRETLRGLQ 782 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 +LH++ IHRD+ + N+LL + +K+ DFG + +E R +W APE Sbjct 783 HLHSKGVIHRDIKSDNILLSMEGNIKLTDFGFCATI---NEAQSKRTTMVGTPYWMAPEV 839 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + ++ D+WS G+ E++ + + L IA ++ + L Sbjct 840 VTRKEYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALWLIATNGTPHIKDEQSLSPVF 898 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 R + + + + R + +L+ Sbjct 899 R---------DFLYFA---LKVDPEKRASAHDLL 920 Score = 184 bits (468), Expect = 2e-46, Method: Composition-based stats. Identities = 60/315 (19%), Positives = 103/315 (33%), Gaps = 44/315 (14%) Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 R + A +L ++ ++ + +GQG VY G Sbjct 650 RQSNAIDVVASLKRICSDGDPREIYRGFTKIGQGASGGVYTGH----------------- 692 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 +RG V +K ++ +M + SH ++ + E Sbjct 693 -------ERGSNRLVAIKQMNLEQQPKKDLIINEILVMKESSHPNIVNFIDSYLCAGELW 745 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 +V EY+E G L + + V ++ L +L +K ++H ++ NILL+ Sbjct 746 VVMEYMEGGSLTDVV--TFNIMTEGQIASVCRETLRGLQHLHSKGVIHRDIKSDNILLSM 803 Query 745 LGLAEGTSPFIKLSDPGVGLGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGF 800 G IKL+D G R V W+APE + +D W Sbjct 804 EG-------NIKLTDFGFCATINEAQSKRTTMVGTPYWMAPEVVT--RKEYGRKVDIWSL 854 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP----EPSCPQLATLTSQCLTYEPTQR 856 G +E+ +GE P + SP + P L +P +R Sbjct 855 GIMAIEMI-EGEPPYLTESPLRALWLIATNGTPHIKDEQSLSPVFRDFLYFALKVDPEKR 913 Query 857 PSFRTILRDLTRLQP 871 S +LR + Sbjct 914 ASAHDLLRHDFMNKC 928 >sp|P57059|SIK1_HUMAN Serine/threonine-protein kinase SIK1 OS=Homo sapiens OX=9606 GN=SIK1 PE=1 SV=2 Length=783 Score = 221 bits (564), Expect = 5e-59, Method: Composition-based stats. Identities = 66/273 (24%), Positives = 107/273 (39%), Gaps = 29/273 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTL 954 + R LG+G+F V L + T VA+K + K + +E+ +++ L Sbjct 26 FYDIERTLGKGNFAVVKL----ARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLL 81 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAY 1013 H HIIK E + L +V E+ G + DYL + + + QI + Y Sbjct 82 NHPHIIKLYQVMETKD--MLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEY 139 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 H H +HRDL N+LLD + +K+ DFG G + SP + APE Sbjct 140 CHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEP---LSTWCGSPP-YAAPEVF 195 Query 1074 KEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + ++ D+WS GV LY L+ P + L + + G Sbjct 196 EGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGP---------------NLPTLRQRVLEG- 239 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 R P + L++ + + R T + Sbjct 240 RFRIPFFMSQDCESLIRRMLVVDPARRITIAQI 272 Score = 200 bits (509), Expect = 5e-52, Method: Composition-based stats. Identities = 66/351 (19%), Positives = 117/351 (33%), Gaps = 40/351 (11%) Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620 ++IM A P Q RV +I LG+G V R RV Sbjct 1 MVIMSEFSADPAGQGQGQQKPLRVGFYDIE--RTLGKGNFAVVKLARHRV---------- 48 Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCV 678 + +V +K++D + D + Y LM ++H H+ ++ V Sbjct 49 --------------TKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVME 94 Query 679 RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGR 738 +VTE+ ++G + +L GH+ Q+ SA+ Y + ++VH ++ Sbjct 95 TKDMLYIVTEFAKNGEMFDYLTSN-GHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTE 153 Query 739 NILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAM 795 N+LL + IKL+D G G P+ APE G + Sbjct 154 NLLLD-------GNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYE-GPQL 205 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855 D W G L + P+ ++ + + R+P +L + L +P + Sbjct 206 DIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDPAR 265 Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906 R + I + L + + + G Sbjct 266 RITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSNLGDYDEQALGIMQTLG 316 >sp|A0A0B4J2F2|SIK1B_HUMAN Putative serine/threonine-protein kinase SIK1B OS=Homo sapiens OX=9606 GN=SIK1B PE=5 SV=1 Length=783 Score = 221 bits (564), Expect = 5e-59, Method: Composition-based stats. Identities = 66/273 (24%), Positives = 107/273 (39%), Gaps = 29/273 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTL 954 + R LG+G+F V L + T VA+K + K + +E+ +++ L Sbjct 26 FYDIERTLGKGNFAVVKL----ARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLL 81 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAY 1013 H HIIK E + L +V E+ G + DYL + + + QI + Y Sbjct 82 NHPHIIKLYQVMETKD--MLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEY 139 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 H H +HRDL N+LLD + +K+ DFG G + SP + APE Sbjct 140 CHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEP---LSTWCGSPP-YAAPEVF 195 Query 1074 KEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + ++ D+WS GV LY L+ P + L + + G Sbjct 196 EGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGP---------------NLPTLRQRVLEG- 239 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 R P + L++ + + R T + Sbjct 240 RFRIPFFMSQDCESLIRRMLVVDPARRITIAQI 272 Score = 200 bits (509), Expect = 5e-52, Method: Composition-based stats. Identities = 66/351 (19%), Positives = 117/351 (33%), Gaps = 40/351 (11%) Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620 ++IM A P Q RV +I LG+G V R RV Sbjct 1 MVIMSEFSADPAGQGQGQQKPLRVGFYDIE--RTLGKGNFAVVKLARHRV---------- 48 Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCV 678 + +V +K++D + D + Y LM ++H H+ ++ V Sbjct 49 --------------TKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVME 94 Query 679 RGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGR 738 +VTE+ ++G + +L GH+ Q+ SA+ Y + ++VH ++ Sbjct 95 TKDMLYIVTEFAKNGEMFDYLTSN-GHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTE 153 Query 739 NILLARLGLAEGTSPFIKLSDPGVG---LGALSREERVERIPWLAPECLPGGANSLSTAM 795 N+LL + IKL+D G G P+ APE G + Sbjct 154 NLLLD-------GNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYE-GPQL 205 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQ 855 D W G L + P+ ++ + + R+P +L + L +P + Sbjct 206 DIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDPAR 265 Query 856 RPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEG 906 R + I + L + + + G Sbjct 266 RITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSNLGDYDEQALGIMQTLG 316 >sp|Q40531|NTF6_TOBAC Mitogen-activated protein kinase homolog NTF6 OS=Nicotiana tabacum OX=4097 GN=NTF6 PE=2 SV=1 Length=371 Score = 211 bits (537), Expect = 5e-59, Method: Composition-based stats. Identities = 77/337 (23%), Positives = 133/337 (39%), Gaps = 35/337 (10%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL- 932 + + +Y+ I+ +G G +G V TN T E VA+K + Sbjct 15 PTHEGKYVEYNVLGNFFEVTSKYIPPIQPVGRGAYGMVCC----ATNSETKEEVAIKKIG 70 Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK---SLQLVMEYVPLGSLRDY 989 A +EI +L + HE+IIK K + + +V E + L Sbjct 71 NAFENRIDAKRTLREIKLLSHMDHENIIKIKDIVRPPDREEFNDVYIVYELMD-TDLHQI 129 Query 990 LPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAV 1048 + ++ F Q+ G+ Y+H+ + +HRDL N+LL+ + +KI DFGLA+ Sbjct 130 IRSSQALTDDHCQYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKICDFGLARTT 189 Query 1049 PEGHEYYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 E + ++ APE L ++ A D+WS G L EL+ Sbjct 190 SEAD----FMTEYVVTRWYRAPELLLNCTEYTAAIDIWSVGCILMELIKREPLFPGRDYA 245 Query 1108 -----FLELIGIAQ----GQMTVLRLTELLERGERLPR-------PDKCPCEVYHLMKNC 1151 + L+G + G + + ++ R+PR PD P + L + Sbjct 246 QQLGLIIALLGSPEDSDLGFLRSDNARKYVKHLPRVPRHPFSQKFPDVSPLAL-DLAERM 304 Query 1152 WETEASFRPTFENLI--PILKTVHEKYQGQA-PSVFS 1185 + + R T E+ + P L ++HE + S F+ Sbjct 305 LVFDPAKRITVEDALNHPFLISLHEINEEPVCDSPFN 341 Score = 132 bits (333), Expect = 5e-32, Method: Composition-based stats. Identities = 41/238 (17%), Positives = 79/238 (33%), Gaps = 44/238 (18%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 F V K I + +G+G V + + V Sbjct 30 FFEVTSKYIPPIQPVGRGAYGMVC------------------------CATNSETKEEVA 65 Query 641 LKVLDPSHHDIALAF--YETASLMSQVSHTHLAFVHGVCV-----RGPENIMVTEYVEHG 693 +K + + + A L+S + H ++ + + + +V E ++ Sbjct 66 IKKIGNAFENRIDAKRTLREIKLLSHMDHENIIKIKDIVRPPDREEFNDVYIVYELMD-T 124 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L +R + + QL L Y+ + N++H ++ N+LL + Sbjct 125 DLHQIIRSSQA-LTDDHCQYFLYQLLRGLKYVHSANVLHRDLKPSNLLLN-------ANC 176 Query 754 FIKLSDPGVGLGALS---REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 +K+ D G+ E V + APE L + A+D W G L+E+ Sbjct 177 DLKICDFGLARTTSEADFMTEYVVTRWYRAPELLLNCTE-YTAAIDIWSVGCILMELI 233 >sp|Q9LVP0|Y5639_ARATH Probable leucine-rich repeat receptor-like protein kinase At5g63930 OS=Arabidopsis thaliana OX=3702 GN=At5g63930 PE=1 SV=1 Length=1102 Score = 225 bits (574), Expect = 5e-59, Method: Composition-based stats. Identities = 76/339 (22%), Positives = 127/339 (37%), Gaps = 22/339 (6%) Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902 +L L +RP D+ + V + Sbjct 750 SLMLIALIVYLMRRPVRTVASSAQDGQPSEMSLDIYFPPKEGFTFQDLVAATDNFDESFV 809 Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH----RSGWKQEIDILRTLYHEH 958 +G G G V G +AVK L ++ + + ++ EI L + H + Sbjct 810 VGRGACGTVYKAVLPA-----GYTLAVKKLASNHEGGNNNNVDNSFRAEILTLGNIRHRN 864 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHA 1016 I+K G C QG L+ EY+P GSL + L S + ++ A +G+AYLH Sbjct 865 IVKLHGFCNHQGSN--LLLYEYMPKGSLGEILHDPSCNLDWSKRFKIALGAAQGLAYLHH 922 Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 HRD+ + N+LLD+ +GDFGLAK + H + + APE Sbjct 923 DCKPRIFHRDIKSNNILLDDKFEAHVGDFGLAKVIDMPHS--KSMSAIAGSYGYIAPEYA 980 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 K SD++S+GV L ELLT Q P + +++ + + L+ + Sbjct 981 YTMKVTEKSDIYSYGVVLLELLTGKAPVQ-PIDQGGDVVNWVRSYIRRDALSSGVLDARL 1039 Query 1134 LPRPDKCPCEV---YHLMKNCWETEASFRPTFENLIPIL 1169 ++ + + C RP+ ++ +L Sbjct 1040 TLEDERIVSHMLTVLKIALLCTSVSPVARPSMRQVVLML 1078 Score = 190 bits (483), Expect = 6e-48, Method: Composition-based stats. Identities = 54/314 (17%), Positives = 102/314 (32%), Gaps = 69/314 (22%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + +G+G VY+ L + +K L Sbjct 800 ATDNFDESFVVGRGACGTVYKAVLPAGYTL-------------------------AVKKL 834 Query 645 DPSHH-----DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +H ++ +F + + H ++ +HG C N+++ EY+ G L L Sbjct 835 ASNHEGGNNNNVDNSFRAEILTLGNIRHRNIVKLHGFCNHQGSNLLLYEYMPKGSLGEIL 894 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIK 756 ++ + + +A A L+YL + + H ++ NILL A Sbjct 895 HDPSCNLDWSKRFKIALGAAQGLAYLHHDCKPRIFHRDIKSNNILLDDKFEAH------- 947 Query 757 LSDPGVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 + D G+ + S ++APE ++ D + +G LLE+ G Sbjct 948 VGDFGLAKVIDMPHSKSMSAIAGSYGYIAPEYA--YTMKVTEKSDIYSYGVVLLELL-TG 1004 Query 812 EAPLQSRSPSEKEHFYQRQH--------------------RLPEPSCPQLATLTSQCLTY 851 +AP+Q + R + R+ L + C + Sbjct 1005 KAPVQPIDQGGDVVNWVRSYIRRDALSSGVLDARLTLEDERIVSHMLTVL-KIALLCTSV 1063 Query 852 EPTQRPSFRTILRD 865 P RPS R ++ Sbjct 1064 SPVARPSMRQVVLM 1077 >sp|Q12263|GIN4_YEAST Serine/threonine-protein kinase GIN4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=GIN4 PE=1 SV=1 Length=1142 Score = 225 bits (574), Expect = 5e-59, Method: Composition-based stats. Identities = 76/290 (26%), Positives = 118/290 (41%), Gaps = 40/290 (14%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS------------- 942 K LG G GKV L N TG+ AVK + Sbjct 18 PWKLGETLGLGSTGKVQL----ARNGSTGQEAAVKVISKAVFNTGNVSGTSIVGSTTPDA 73 Query 943 ---GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLA 998 G ++EI I++ L H ++++ E + L LV+EY G L + L R + Sbjct 74 LPYGIEREIIIMKLLNHPNVLRLYDVWETNTD--LYLVLEYAEKGELFNLLVERGPLPEH 131 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 + + F +QI G++Y HA +HRDL N+LLD+ +KI DFG+A EG ++ Sbjct 132 EAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEG----KLL 187 Query 1059 EDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 E + APE + + +ASDVWS GV L+ LLT L Sbjct 188 ETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTL------ 241 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L ++ + +P D+ E L++ + R +++ Sbjct 242 ------LLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILK 285 Score = 167 bits (423), Expect = 1e-40, Method: Composition-based stats. Identities = 56/299 (19%), Positives = 104/299 (35%), Gaps = 25/299 (8%) Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 ++ + + + ++ LG G+ V R +G K+ + G G Sbjct 7 SIPAIKDNTIGPWKL--GETLGLGSTGKV--QLARNGSTGQEAAVKVISKAVFNTGNVSG 62 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 + V + + +M ++H ++ ++ V + +V EY E G Sbjct 63 TSI-----VGSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGE 117 Query 695 LDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPF 754 L L ERG +P + +Q+ +SY +VH ++ N+LL Sbjct 118 LFNLL-VERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHK-------YN 169 Query 755 IKLSDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 IK++D G+ E + APE + G A D W G L + Sbjct 170 IKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQ-GFASDVWSCGVILFALLTGR 228 Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLA----TLTSQCLTYEPTQRPSFRTILRDL 866 + ++ PS +++ L + LT +P +R R IL+ Sbjct 229 LPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHP 287 >sp|Q9C8M9|SRF6_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 6 OS=Arabidopsis thaliana OX=3702 GN=SRF6 PE=1 SV=1 Length=719 Score = 220 bits (561), Expect = 5e-59, Method: Composition-based stats. Identities = 66/273 (24%), Positives = 121/273 (44%), Gaps = 23/273 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIK 961 LGEG FG+V +D G+++AVK + + P + + + + L H ++ K Sbjct 422 LGEGTFGRVYRAEFD-----DGKVLAVKKIDSSALPHGMTDDFIEMVSKIANLDHPNVTK 476 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMAYLH- 1015 G C + G+ +V E+ GSL D+L ++ + A + YLH Sbjct 477 LVGYCAEHGQH--LVVYEFHKNGSLHDFLHLSEEESKALVWNSRVKIALGTARALEYLHE 534 Query 1016 --AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + + +++ + N+LLD++ + D GLA +P +E ++G + APE Sbjct 535 VCSPSIVDKNIKSANILLDSELNPHLSDSGLASFLPTANELLNQTDEG-----YSAPEVS 589 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK-FLELIGIAQGQM-TVLRLTELLERG 1131 ++ SD++SFGV + ELLT S ++ L+ A Q+ + L ++++ Sbjct 590 MSGQYSLKSDIYSFGVVMLELLTGRKPFDSTRSRSEQSLVRWATPQLHDIDALAKMVDPA 649 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + P K ++ C + E FRP Sbjct 650 LKGLYPVKSLSRFADVIALCVQPEPEFRPPMSE 682 Score = 180 bits (457), Expect = 1e-45, Method: Composition-based stats. Identities = 67/329 (20%), Positives = 120/329 (36%), Gaps = 62/329 (19%) Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620 + + + P + L ++ ++ + + LG+GT VY + Sbjct 388 IAVKKSTVVVPSNVRLYSVADLQIATGSFSVDNLLGEGTFGRVYRA-------------E 434 Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCV 678 DD L +K +D S H + F E S ++ + H ++ + G C Sbjct 435 FDDGKVL------------AVKKIDSSALPHGMTDDFIEMVSKIANLDHPNVTKLVGYCA 482 Query 679 RGPENIMVTEYVEHGPLDVWLR---RERGHVPMAWKMVVAQQLASALSYLE---NKNLVH 732 ++++V E+ ++G L +L E + ++ +A A AL YL + ++V Sbjct 483 EHGQHLVVYEFHKNGSLHDFLHLSEEESKALVWNSRVKIALGTARALEYLHEVCSPSIVD 542 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI--PWLAPECLPGGANS 790 N+ NILL LSD G+ + E + + + APE G Sbjct 543 KNIKSANILLDSELNPH-------LSDSGLASFLPTANELLNQTDEGYSAPEVSMSG--Q 593 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL----------------- 833 S D + FG +LE+ + +RS SE+ +L Sbjct 594 YSLKSDIYSFGVVMLELLTGRKPFDSTRSRSEQSLVRWATPQLHDIDALAKMVDPALKGL 653 Query 834 -PEPSCPQLATLTSQCLTYEPTQRPSFRT 861 P S + A + + C+ EP RP Sbjct 654 YPVKSLSRFADVIALCVQPEPEFRPPMSE 682 >sp|A0A1S4CGX4|SIPKK_TOBAC Mitogen-activated protein kinase kinase SIPKK OS=Nicotiana tabacum OX=4097 GN=SIPKK PE=1 SV=1 Length=357 Score = 210 bits (535), Expect = 5e-59, Method: Composition-based stats. Identities = 64/267 (24%), Positives = 120/267 (45%), Gaps = 20/267 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G+ G V L + TG+ A+K ++ + R QE+ I ++ +++ Sbjct 76 IGKGNGGIVRLVQHK----WTGQFFALKVIQMNIEESMRKHIAQELRINQSSQCPYVVIS 131 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHA-QHYI 1020 D G ++ +++EY+ GSL D+L + +I L +Q+ +G+ YLH +H I Sbjct 132 YQSFFDNG--AISIILEYMDGGSLADFLKKVKTIPERYLAAICKQVLKGLWYLHHEKHII 189 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDL N+L+++ VKI DFG++ + + + +PE + + Y Sbjct 190 HRDLKPSNLLINHIGDVKITDFGVSAVLASTSG---LANTFVGTYNYMSPERILGGAYGY 246 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE-LLERGERLPRPDK 1139 SD+WS G+ L E T P +G + V L E ++++ PD+ Sbjct 247 RSDIWSLGLVLLECATGVFPYSPPQAD--------EGWVNVYELMETIVDQPAPSAPPDQ 298 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLI 1166 + + C + + R + L+ Sbjct 299 FSPQFCSFISACVQKDQKDRLSANELM 325 Score = 160 bits (405), Expect = 1e-41, Method: Composition-based stats. Identities = 59/330 (18%), Positives = 117/330 (35%), Gaps = 60/330 (18%) Query 561 LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGK 620 I+ + +P + S +++ + + +G+G V Sbjct 45 RIVSQSEVEAPSVIQPSD---NQLCLADFEAVKVIGKGNGGIV----------------- 84 Query 621 MDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVR 679 LV + GQ LKV+ + + + + ++ + Sbjct 85 -----RLVQHKWTGQFF--ALKVIQMNIEESMRKHIAQELRINQSSQCPYVVISYQSFFD 137 Query 680 GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE-NKNLVHGNVCGR 738 ++ EY++ G L +L++ + +P + + +Q+ L YL K+++H ++ Sbjct 138 NGAISIILEYMDGGSLADFLKKVK-TIPERYLAAICKQVLKGLWYLHHEKHIIHRDLKPS 196 Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSRE----ERVERIPWLAPECLPGGANSLSTA 794 N+L+ +G +K++D GV S V +++PE + GGA Sbjct 197 NLLINHIGD-------VKITDFGVSAVLASTSGLANTFVGTYNYMSPERILGGAYGY--R 247 Query 795 MDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL-------------PEPSCPQL 841 D W G LLE C G P SP + + + + L P+ PQ Sbjct 248 SDIWSLGLVLLE-CATGVFPY---SPPQADEGWVNVYELMETIVDQPAPSAPPDQFSPQF 303 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 + S C+ + R S ++R Sbjct 304 CSFISACVQKDQKDRLSANELMRHPFITMY 333 >sp|I1Z695|EREC2_ORYSJ LRR receptor-like serine/threonine-protein kinase ER2 OS=Oryza sativa subsp. japonica OX=39947 GN=ER2 PE=1 SV=2 Length=986 Score = 224 bits (571), Expect = 5e-59, Method: Composition-based stats. Identities = 73/342 (21%), Positives = 129/342 (38%), Gaps = 26/342 (8%) Query 841 LATLTSQCL---TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYL 897 L L + C P + + L +L +N + + L Sbjct 594 LMILAAACWPHWAQVPKDVSLCKPDIHALPSSNVPPKLVILHMNMAFLVYEDIMRMTENL 653 Query 898 KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHE 957 + +G G V + VA+K L A PQ ++ E++ + ++ H Sbjct 654 SEKYIIGYGASSTVYKCVLKNC-----KPVAIKKLYAHY-PQSLKEFETELETVGSIKHR 707 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLFAQQICEGMA 1012 +++ +G L +Y+ GSL D L + + L A +G+A Sbjct 708 NLVSLQGYSLSPAGN--LLFYDYLENGSLWDVLHAGSSKKQKLDWEARLRIALGAAQGLA 765 Query 1013 YLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 YLH IHRD+ ++N+LLD D + DFG+AK++ + + + Sbjct 766 YLHHDCNPRIIHRDVKSKNILLDKDYEAHLADFGIAKSLCTSKTH--TSTYVMGTIGYID 823 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE + SDV+S+G+ L ELLT P L + + + E+++ Sbjct 824 PEYACTSRLNEKSDVYSYGIVLLELLTGK----KPVDNECNLHHLILSKAADNTVMEMVD 879 Query 1130 RGERLPRPD-KCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 D +V+ L C + + S RPT ++ +L Sbjct 880 PDIADTCKDLGEVKKVFQLALLCSKRQPSDRPTMHEVVRVLD 921 Score = 184 bits (468), Expect = 3e-46, Method: Composition-based stats. Identities = 56/329 (17%), Positives = 117/329 (36%), Gaps = 60/329 (18%) Query 573 TLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 +N++ L + + + + +++ +G G + VY+ L+ Sbjct 635 HMNMAFLVYEDIMRMTENLSEKYIIGYGASSTVYKCVLKNCKP----------------- 677 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 V +K L + F + + H +L + G + N++ +Y+ Sbjct 678 --------VAIKKLYAHYPQSLKEFETELETVGSIKHRNLVSLQGYSLSPAGNLLFYDYL 729 Query 691 EHGPLDVWLR---RERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLAR 744 E+G L L ++ + ++ +A A L+YL N ++H +V +NILL + Sbjct 730 ENGSLWDVLHAGSSKKQKLDWEARLRIALGAAQGLAYLHHDCNPRIIHRDVKSKNILLDK 789 Query 745 LGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLPGGANSLSTAMDKWG 799 A L+D G+ + + + I ++ PE + L+ D + Sbjct 790 DYEAH-------LADFGIAKSLCTSKTHTSTYVMGTIGYIDPEYA--CTSRLNEKSDVYS 840 Query 800 FGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT-------------LTS 846 +G LLE+ + + + + E P +A L Sbjct 841 YGIVLLELLTGKKPVDNECNLHHLILSKAADNTVMEMVDPDIADTCKDLGEVKKVFQLAL 900 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 C +P+ RP+ ++R L L + Sbjct 901 LCSKRQPSDRPTMHEVVRVLDCLVYPDPP 929 >sp|Q7FAZ0|LERK4_ORYSJ G-type lectin S-receptor-like serine/threonine-protein kinase LECRK4 OS=Oryza sativa subsp. japonica OX=39947 GN=LECRK4 PE=3 SV=1 Length=804 Score = 222 bits (565), Expect = 6e-59, Method: Composition-based stats. Identities = 66/274 (24%), Positives = 112/274 (41%), Gaps = 14/274 (5%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G G V D G +AVK + + + E+ + YH+++++ Sbjct 520 LGTGASGIVYKGQLQ---DELGTYIAVKKIDKIQHETEKE-FAVEVQTIGRTYHKNLVRM 575 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH---AQH 1018 G C + E+ LV E++ GSL +L + + A + G+ YLH + Sbjct 576 LGFCNEGTER--LLVYEFMVNGSLNRFLFSGVRPLWSLRVQLALGVARGLLYLHEECSTQ 633 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IH D+ +N+LLD++ + KI DFGLAK + + + APE K Sbjct 634 IIHCDIKPQNILLDDNFIAKISDFGLAKLLRTNQT--QTYTGIRGTRGYVAPEWFKNVGI 691 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPR 1136 DV+SFGV L EL+ + + + + L A R+ L++ + Sbjct 692 TAKVDVYSFGVILLELICCRQNVEMEAAEEEQSILTYWANDCYRCGRVDLLVDGDDEAKL 751 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 K + C + E + RP+ + +L Sbjct 752 NIKKVERFVAVALWCLQEEPTMRPSILKVTQMLD 785 Score = 206 bits (524), Expect = 1e-53, Method: Composition-based stats. Identities = 59/318 (19%), Positives = 115/318 (36%), Gaps = 59/318 (19%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L L S+ +++ LG G VY+G+L+ E Sbjct 499 LPLKAFSYAELEKATDGFKEVLGTGASGIVYKGQLQDEL--------------------- 537 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + +K +D H+ F + + H +L + G C G E ++V E++ +G Sbjct 538 --GTYIAVKKIDKIQHETEKEFAVEVQTIGRTYHKNLVRMLGFCNEGTERLLVYEFMVNG 595 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEG 750 L+ +L + + ++ +A +A L YL + ++H ++ +NILL Sbjct 596 SLNRFLFSGVRPL-WSLRVQLALGVARGLLYLHEECSTQIIHCDIKPQNILLD------- 647 Query 751 TSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + K+SD G+ + + + ++APE ++ +D + FG LL Sbjct 648 DNFIAKISDFGLAKLLRTNQTQTYTGIRGTRGYVAPEWFKN--VGITAKVDVYSFGVILL 705 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQH------------------RLPEPSCPQLATLTSQ 847 E+ + + E+ + +L + + Sbjct 706 ELICCRQNVEMEAAEEEQSILTYWANDCYRCGRVDLLVDGDDEAKLNIKKVERFVAVALW 765 Query 848 CLTYEPTQRPSFRTILRD 865 CL EPT RPS + + Sbjct 766 CLQEEPTMRPSILKVTQM 783 >sp|Q25AG2|LERK4_ORYSI G-type lectin S-receptor-like serine/threonine-protein kinase LECRK4 OS=Oryza sativa subsp. indica OX=39946 GN=LECRK4 PE=3 SV=1 Length=804 Score = 222 bits (565), Expect = 6e-59, Method: Composition-based stats. Identities = 66/274 (24%), Positives = 112/274 (41%), Gaps = 14/274 (5%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G G V D G +AVK + + + E+ + YH+++++ Sbjct 520 LGTGASGIVYKGQLQ---DELGTYIAVKKIDKIQHETEKE-FAVEVQTIGRTYHKNLVRM 575 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-LAQLLLFAQQICEGMAYLH---AQH 1018 G C + E+ LV E++ GSL +L + + A + G+ YLH + Sbjct 576 LGFCNEGTER--LLVYEFMVNGSLNRFLFSGVRPLWSLRVQLALGVARGLLYLHEECSTQ 633 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IH D+ +N+LLD++ + KI DFGLAK + + + APE K Sbjct 634 IIHCDIKPQNILLDDNFIAKISDFGLAKLLRTNQT--QTYTGIRGTRGYVAPEWFKNVGI 691 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLE--LIGIAQGQMTVLRLTELLERGERLPR 1136 DV+SFGV L EL+ + + + + L A R+ L++ + Sbjct 692 TAKVDVYSFGVILLELICCRQNVEMEAAEEEQSILTYWANDCYRCGRVDLLVDGDDEAKL 751 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 K + C + E + RP+ + +L Sbjct 752 NIKKVERFVAVALWCLQEEPTMRPSILKVTQMLD 785 Score = 206 bits (524), Expect = 1e-53, Method: Composition-based stats. Identities = 59/318 (19%), Positives = 115/318 (36%), Gaps = 59/318 (19%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 L L S+ +++ LG G VY+G+L+ E Sbjct 499 LPLKAFSYAELEKATDGFKEVLGTGASGIVYKGQLQDEL--------------------- 537 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 + +K +D H+ F + + H +L + G C G E ++V E++ +G Sbjct 538 --GTYIAVKKIDKIQHETEKEFAVEVQTIGRTYHKNLVRMLGFCNEGTERLLVYEFMVNG 595 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEG 750 L+ +L + + ++ +A +A L YL + ++H ++ +NILL Sbjct 596 SLNRFLFSGVRPL-WSLRVQLALGVARGLLYLHEECSTQIIHCDIKPQNILLD------- 647 Query 751 TSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + K+SD G+ + + + ++APE ++ +D + FG LL Sbjct 648 DNFIAKISDFGLAKLLRTNQTQTYTGIRGTRGYVAPEWFKN--VGITAKVDVYSFGVILL 705 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQH------------------RLPEPSCPQLATLTSQ 847 E+ + + E+ + +L + + Sbjct 706 ELICCRQNVEMEAAEEEQSILTYWANDCYRCGRVDLLVDGDDEAKLNIKKVERFVAVALW 765 Query 848 CLTYEPTQRPSFRTILRD 865 CL EPT RPS + + Sbjct 766 CLQEEPTMRPSILKVTQM 783 >sp|Q9C823|Y1523_ARATH C-type lectin receptor-like tyrosine-protein kinase At1g52310 OS=Arabidopsis thaliana OX=3702 GN=At1g52310 PE=2 SV=1 Length=552 Score = 216 bits (551), Expect = 6e-59, Method: Composition-based stats. Identities = 73/264 (28%), Positives = 120/264 (45%), Gaps = 15/264 (6%) Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 G VAVK LK Q + + EI LYH +++ KGCC D GE+ +V E++ Sbjct 288 SDGTKVAVKRLKR-SSFQRKKEFYSEIRRAAKLYHPNVVAIKGCCYDHGER--FIVYEFI 344 Query 982 PLGSLRDYLPR-----HSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDN 1033 G L +L S+ L A + +G+A+LH + +HRD+ A NVLLD Sbjct 345 ASGPLDRWLHHVPRGGRSLDWNMRLNIATTLAQGIAFLHDKVKPQVVHRDIRASNVLLDE 404 Query 1034 DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYE 1093 + + GL+K VP R + APE + + SDV+SFGV L E Sbjct 405 EFGAHLMGVGLSKFVPWEVMQERT-VMAGGTYGYLAPEYVYRNELTTKSDVYSFGVLLLE 463 Query 1094 LLTHCDSSQSPPTK--FLELIGIAQGQMTVLRLTELLERGERLPRPDKC-PCEVYHLMKN 1150 +++ +Q+ + + + A + R E+L+ P+ C +V L+ + Sbjct 464 IVSGRRPTQAVNSSVGWQSIFEWATPLVQANRWLEILDPVITCGLPEACVVQKVVDLVYS 523 Query 1151 CWETEASFRPTFENLIPILKTVHE 1174 C + S RP +++ L+ + + Sbjct 524 CTQNVPSMRPRMSHVVHQLQQLVQ 547 Score = 172 bits (436), Expect = 4e-44, Method: Composition-based stats. Identities = 58/263 (22%), Positives = 98/263 (37%), Gaps = 32/263 (12%) Query 637 LRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +V +K L S FY +++ H ++ + G C E +V E++ GPLD Sbjct 291 TKVAVKRLKRSSFQRKKEFYSEIRRAAKLYHPNVVAIKGCCYDHGERFIVYEFIASGPLD 350 Query 697 VWLRR-ERGHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEG 750 WL RG + W ++ +A LA +++L +K +VH ++ N+LL A Sbjct 351 RWLHHVPRGGRSLDWNMRLNIATTLAQGIAFLHDKVKPQVVHRDIRASNVLLDEEFGAHL 410 Query 751 TSPFIKLSDPGVGLGALSREERV--ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + LS V + + +LAPE + N L+T D + FG LLEI Sbjct 411 M--GVGLSKF-VPWEVMQERTVMAGGTYGYLAPEYV--YRNELTTKSDVYSFGVLLLEIV 465 Query 809 FDGEAPLQSRSPSEKEHFYQRQHRLPE-------------------PSCPQLATLTSQCL 849 S + ++ L + ++ L C Sbjct 466 SGRRPTQAVNSSVGWQSIFEWATPLVQANRWLEILDPVITCGLPEACVVQKVVDLVYSCT 525 Query 850 TYEPTQRPSFRTILRDLTRLQPH 872 P+ RP ++ L +L Sbjct 526 QNVPSMRPRMSHVVHQLQQLVQP 548 >sp|P06244|KAPA_YEAST cAMP-dependent protein kinase type 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TPK1 PE=1 SV=3 Length=397 Score = 211 bits (538), Expect = 6e-59, Method: Composition-based stats. Identities = 70/324 (22%), Positives = 120/324 (37%), Gaps = 45/324 (14%) Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919 T + + + + + + +R LG G FG+V L Sbjct 50 ETQEKPKQPHVTYYNEEQYKQFIAQARVTSGKYSLQDFQILRTLGTGSFGRVHLI----R 105 Query 920 NDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLV 977 + G A+K LK + + E +L + H II+ G +D + + ++ Sbjct 106 SRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDA--QQIFMI 163 Query 978 MEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRL 1036 M+Y+ G L L + +A ++C + YLH++ I+RDL N+LLD + Sbjct 164 MDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGH 223 Query 1037 VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT 1096 +KI DFG AK VP+ V + APE + + + D WSFG+ +YE+L Sbjct 224 IKITDFGFAKYVPD------VTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLA 277 Query 1097 HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEA 1156 T+ ++L R P +V L+ + Sbjct 278 GYTPF--------------YDSNTMKTYEKILNAELRF--PPFFNEDVKDLLSRLITRDL 321 Query 1157 SFR--------------PTFENLI 1166 S R P F+ ++ Sbjct 322 SQRLGNLQNGTEDVKNHPWFKEVV 345 Score = 177 bits (449), Expect = 4e-47, Method: Composition-based stats. Identities = 58/322 (18%), Positives = 113/322 (35%), Gaps = 41/322 (13%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 ++ L LG G+ V+ R R G + +E+ V LK ++ Sbjct 85 QDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVL-------------KKEIVVRLKQVEH 131 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 ++ + ++S V+H + + G + M+ +Y+E G L LR+ + Sbjct 132 TN--------DERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQ-RF 182 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 P A ++ AL YL +K++++ ++ NILL + G IK++D G Sbjct 183 PNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNG-------HIKITDFGFAKYV 235 Query 767 LSREER-VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 ++APE + + ++D W FG + E+ S + E Sbjct 236 PDVTYTLCGTPDYIAPEVVST--KPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEK 293 Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885 + R P + L S+ +T + + + L LQ Sbjct 294 ILNAELRFPPFFNEDVKDLLSRLITRD---------LSQRLGNLQNGTEDVKNHPWFKEV 344 Query 886 ASDPTVFHKRYLKKIRDLGEGH 907 + + + +G Sbjct 345 VWEKLLSRNIETPYEPPIQQGQ 366 >sp|Q8BWQ5|DCLK3_MOUSE Serine/threonine-protein kinase DCLK3 OS=Mus musculus OX=10090 GN=Dclk3 PE=1 SV=2 Length=790 Score = 221 bits (564), Expect = 6e-59, Method: Composition-based stats. Identities = 75/324 (23%), Positives = 127/324 (39%), Gaps = 29/324 (9%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 +P R ++ R + + P + +++ +G+G+F Sbjct 467 EKKPGGLGERRAPEKESKRKLEEKRPERPSGRKPRPKGIISADVEKHYDIGGVIGDGNFA 526 Query 910 KVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 V + + T + A+K + EI I+++L H +I+K E + Sbjct 527 TVK----ECRHRETKQAYAMKMIDKSQLKGKEDIVDSEILIIQSLSHPNIVKLHEVYETE 582 Query 970 GEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARN 1028 E + L+MEYV G L D + + + + +C+ + ++H ++ +HRD+ N Sbjct 583 AE--IYLIMEYVQGGDLFDAIVENVKFPEPEAAVMITDLCKALVHMHDKNIVHRDVKPEN 640 Query 1029 VLL----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDV 1084 +L+ D +K+ DFGLAK V R + APE L E + D+ Sbjct 641 LLVQRNEDKSITLKLADFGLAKYV------VRPIFTVCGTPTYVAPEILSEKGYGLEVDM 694 Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ-GQMTVLRLTELLERGERLPRPDKCPCE 1143 W+ GV LY LL +SP EL I Q GQ L P D Sbjct 695 WAAGVILYILLCGFPPFRSPERDQDELFNIIQVGQFEFLS-----------PYWDNISDA 743 Query 1144 VYHLMKNCWETEASFRPTFENLIP 1167 L++N E + R T E ++ Sbjct 744 AKDLVRNLLEVDPKKRYTAEQVLQ 767 Score = 166 bits (421), Expect = 5e-41, Method: Composition-based stats. Identities = 66/324 (20%), Positives = 109/324 (34%), Gaps = 41/324 (13%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 P+ L R R S R + V++ +G G V E Sbjct 479 PEKESKRKLEEKRPERPSGRKPRPKGIISADVEK-HYDIGGVIGDGNFATVKE------- 530 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE-TASLMSQVSHTHLA 671 R R + +K++D S + ++ +SH ++ Sbjct 531 -----------------CRHRETKQAYAMKMIDKSQLKGKEDIVDSEILIIQSLSHPNIV 573 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 +H V E ++ EYV+ G L + E P V+ L AL ++ +KN+V Sbjct 574 KLHEVYETEAEIYLIMEYVQGGDLFDAI-VENVKFPEPEAAVMITDLCKALVHMHDKNIV 632 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-EERVERIPWLAPECLPGGANS 790 H +V N+L+ R E S +KL+D G+ + ++APE L Sbjct 633 HRDVKPENLLVQRN---EDKSITLKLADFGLAKYVVRPIFTVCGTPTYVAPEILSE--KG 687 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-------HRLPEPSCPQLAT 843 +D W G L I G P +S + E F Q + Sbjct 688 YGLEVDMWAAGVILY-ILLCGFPPFRSPERDQDELFNIIQVGQFEFLSPYWDNISDAAKD 746 Query 844 LTSQCLTYEPTQRPSFRTILRDLT 867 L L +P +R + +L+ Sbjct 747 LVRNLLEVDPKKRYTAEQVLQHPW 770 >sp|A1IVT7|HOG1_BOTFB Mitogen-activated protein kinase hog1 OS=Botryotinia fuckeliana (strain B05.10) OX=332648 GN=hog1 PE=1 SV=1 Length=354 Score = 210 bits (535), Expect = 6e-59, Method: Composition-based stats. Identities = 68/281 (24%), Positives = 107/281 (38%), Gaps = 29/281 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V ++ TG VAVK + K P +E+ +L+ L HE++ Sbjct 24 QPVGMGAFGLVC----SAKDNLTGSNVAVKKIMKPFSTPVLSKRTYRELKLLKHLKHENV 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 DVWS G E+L + + EL+G + LR + Sbjct 192 DVEVDVWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIHTIASENTLRFVQ 251 Query 1127 LLERGERLPRPDK---CPCEVYHLMKNCWETEASFRPTFEN 1164 L + ER P K L++ + R Sbjct 252 SLPKRERQPLASKFTQADPLAIDLLEKMLVFDPRARIKAAE 292 Score = 132 bits (331), Expect = 5e-32, Method: Composition-based stats. Identities = 40/252 (16%), Positives = 81/252 (32%), Gaps = 21/252 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E D + M + +D V +K ++ P ++ Y Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSAKDNLTGSNVAVKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLKHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 + APE + +D W G E+ +G+ + F L Sbjct 177 RYYRAPE-IMLTWQKYDVEVDVWSAGCIFAEML-EGKPLFPGKDH--VNQFSIITELLGT 232 Query 836 PSCPQLATLTSQ 847 P + T+ S+ Sbjct 233 PPDDVIHTIASE 244 >sp|Q8W4S5|Y5371_ARATH Probable LRR receptor-like serine/threonine-protein kinase At5g63710 OS=Arabidopsis thaliana OX=3702 GN=At5g63710 PE=1 SV=1 Length=614 Score = 218 bits (554), Expect = 6e-59, Method: Composition-based stats. Identities = 71/279 (25%), Positives = 116/279 (42%), Gaps = 21/279 (8%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FGKV VAVK L P + +++EI ++ H+++++ Sbjct 295 IGQGGFGKVYRGLL-----PDKTKVAVKRLADYFSPGGEAAFQREIQLISVAVHKNLLRL 349 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFAQQICEGMAYLHAQ 1017 G C E+ LV Y+ S+ L + A G+ YLH Sbjct 350 IGFCTTSSER--ILVYPYMENLSVAYRLRDLKAGEEGLDWPTRKRVAFGSAHGLEYLHEH 407 Query 1018 ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 IHRDL A N+LLDN+ +GDFGLAK V + V + APE L Sbjct 408 CNPKIIHRDLKAANILLDNNFEPVLGDFGLAKLVDTSLTH--VTTQVRGTMGHIAPEYLC 465 Query 1075 EYKFYYASDVWSFGVTLYELLTH---CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 K +DV+ +G+TL EL+T D S+ + + L+ + + RL ++++ Sbjct 466 TGKSSEKTDVFGYGITLLELVTGQRAIDFSRLEEEENILLLDHIKKLLREQRLRDIVDSN 525 Query 1132 ERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 K + + C + RP ++ +L+ Sbjct 526 LT-TYDSKEVETIVQVALLCTQGSPEDRPAMSEVVKMLQ 563 Score = 180 bits (456), Expect = 4e-46, Method: Composition-based stats. Identities = 68/323 (21%), Positives = 106/323 (33%), Gaps = 66/323 (20%) Query 575 NLSQLSFHRV--DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L + S + + + +GQG VY G L Sbjct 273 QLKRFSLREIQLATDSFNESNLIGQGGFGKVYRGLL------------------------ 308 Query 633 RGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 + +V +K L D AF L+S H +L + G C E I+V Y+E Sbjct 309 -PDKTKVAVKRLADYFSPGGEAAFQREIQLISVAVHKNLLRLIGFCTTSSERILVYPYME 367 Query 692 HGPLDVWLRRERG---HVPMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARL 745 + + LR + + + VA A L YL ++H ++ NILL Sbjct 368 NLSVAYRLRDLKAGEEGLDWPTRKRVAFGSAHGLEYLHEHCNPKIIHRDLKAANILLDNN 427 Query 746 GLAEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGF 800 L D G+ + V + +APE L G + S D +G+ Sbjct 428 FEPV-------LGDFGLAKLVDTSLTHVTTQVRGTMGHIAPEYLCTGKS--SEKTDVFGY 478 Query 801 GATLLEICFDGEAPLQSR-------SPSEKEHFYQRQHRLPEPSCPQLAT---------- 843 G TLLE+ A SR + R+ RL + L T Sbjct 479 GITLLELVTGQRAIDFSRLEEEENILLLDHIKKLLREQRLRDIVDSNLTTYDSKEVETIV 538 Query 844 -LTSQCLTYEPTQRPSFRTILRD 865 + C P RP+ +++ Sbjct 539 QVALLCTQGSPEDRPAMSEVVKM 561 >sp|Q66HE5|NUAK2_RAT NUAK family SNF1-like kinase 2 OS=Rattus norvegicus OX=10116 GN=Nuak2 PE=1 SV=1 Length=630 Score = 218 bits (555), Expect = 6e-59, Method: Composition-based stats. Identities = 68/291 (23%), Positives = 114/291 (39%), Gaps = 32/291 (11%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 + + + LG+G +GKV + +G +VA+K+++ D Sbjct 39 MKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKAR-----ESSGRLVAIKSIRKDKIK 93 Query 939 QHRS--GWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSI 995 + ++EI+I+ +L H HII E+ + + +VMEY G L DY+ R + Sbjct 94 DEQDLLHIRREIEIMSSLNHPHIIAIHEVFENSSK--IVIVMEYASRGDLYDYISERPRL 151 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 F +QI + Y H +HRDL N+LLD +KI DFGL+ +G Sbjct 152 NERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDASGNIKIADFGLSNLYHKG---- 207 Query 1056 RVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 + + + +PE + + D WS GV LY L+ K L Sbjct 208 KFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKTL----- 262 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + ++ R P P + L++ R T E++ Sbjct 263 ---------VKQISSGAYREPC---KPSDACGLIRWLLMVNPIRRATLEDV 301 Score = 173 bits (438), Expect = 8e-44, Method: Composition-based stats. Identities = 57/320 (18%), Positives = 94/320 (29%), Gaps = 45/320 (14%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEIT----QLSHLGQGTRTNVYEGRLRVEGS 613 S + SP+ L Q + + L LG+GT V + R Sbjct 22 ESARPLADRLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKAR------ 75 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFY---ETASLMSQVSHTHL 670 V +K + +MS ++H H+ Sbjct 76 -------------------ESSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHI 116 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730 +H V + ++V EY G L ++ ER + +Q+ SAL Y + Sbjct 117 IAIHEVFENSSKIVIVMEYASRGDLYDYI-SERPRLNERDARHFFRQIVSALHYCHQNGI 175 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGG 787 VH ++ NILL S IK++D G+ + + +PE + G Sbjct 176 VHRDLKLENILLD-------ASGNIKIADFGLSNLYHKGKFLQTFCGSPLYASPEIVNGK 228 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQ 847 + +D W G L I G P + L Sbjct 229 PY-VGPEVDSWSLGVLLY-ILVHGTMPFDGQDHKTLVKQISSGAYREPCKPSDACGLIRW 286 Query 848 CLTYEPTQRPSFRTILRDLT 867 L P +R + + Sbjct 287 LLMVNPIRRATLEDVASHWW 306 >sp|P27466|KCC1_YEAST Calcium/calmodulin-dependent protein kinase I OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CMK1 PE=1 SV=2 Length=446 Score = 213 bits (542), Expect = 6e-59, Method: Composition-based stats. Identities = 67/292 (23%), Positives = 113/292 (39%), Gaps = 26/292 (9%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR- 941 + + +K+ + LG G FG V N TGE VAVK L ++ Sbjct 23 MAHVQPASYVNKKKYVFGKTLGAGTFGVVR----QAKNTETGEDVAVKILIKKALKGNKV 78 Query 942 --SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLA 998 E+DIL+ L+H +I+ +K E + + ++ + G L D L + Sbjct 79 QLEALYDELDILQRLHHPNIVAFKDWFESKDK--FYIITQLAKGGELFDRILKKGKFTEE 136 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYY 1055 + +I + Y+H+Q+ +HRDL N+L ++ + + DFG+AK + E Sbjct 137 DAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELL 196 Query 1056 RVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIA 1115 + + APE L + D+WS GV Y LL + ++ + L Sbjct 197 YK---PAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDF-LDECT 252 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 G+ V P D + + + S RPT L+ Sbjct 253 TGEYPV---------KFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLE 295 Score = 157 bits (398), Expect = 7e-40, Method: Composition-based stats. Identities = 48/299 (16%), Positives = 110/299 (37%), Gaps = 43/299 (14%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL-- 641 V++K+ LG GT V + + + G+++ V + Sbjct 32 VNKKKYVFGKTLGAGTFGVVRQAK----------------------NTETGEDVAVKILI 69 Query 642 -KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 K L + + A Y+ ++ ++ H ++ + ++T+ + G L + Sbjct 70 KKALKGNKVQL-EALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRIL 128 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + +G + + ++ SA+ Y+ ++N+VH ++ N+L + + + ++D Sbjct 129 K-KGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLL----YIDKSDESPLVVADF 183 Query 761 GVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 G+ S EE + ++APE L + D W G + A Sbjct 184 GIAKRLKSDEELLYKPAGSLGYVAPEVLTQ--DGHGKPCDIWSIGVITYTLLCGYSAFRA 241 Query 817 SRSPSEKE-----HFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 R + + + HR + + + L +P++RP+ +L D + Sbjct 242 ERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWII 300 >sp|Q6C3J2|IPL1_YARLI Spindle assembly checkpoint kinase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) OX=284591 GN=IPL1 PE=3 SV=1 Length=371 Score = 211 bits (536), Expect = 6e-59, Method: Composition-based stats. Identities = 68/275 (25%), Positives = 116/275 (42%), Gaps = 36/275 (13%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHII 960 LG+G FGKV L + TG + A+K ++ + +++E++I L H +++ Sbjct 105 LGKGKFGKVYLV----KDKKTGFVSALKCMEKKELVEGNVEKQFRREVEIQSNLRHTNVL 160 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019 + G D+ + L++EYV G L L + + Q+ E + YLH ++ Sbjct 161 RLFGHFHDKD--RVYLILEYVVHGELYKLLRNQKRFTESTASSYIYQMSEALLYLHGKNI 218 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ N+LL + +KI DFG + P R + + PE ++ + Sbjct 219 IHRDIKPENILLHFNDTIKISDFGWSVHAPSNR-----RSTLCGTMDYLPPEIVQSRPYD 273 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 DVWS G+ +YE L + P Q T R+ +L R P Sbjct 274 KNVDVWSLGILMYEFLCGAPPFEEPGG----------AQATYRRIVKLDLR-----IPPY 318 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 + L+K + + R F+ LK +H+ Sbjct 319 VSADAADLIKRMLTLDPAKR--FK-----LKDMHK 346 Score = 193 bits (491), Expect = 7e-53, Method: Composition-based stats. Identities = 64/326 (20%), Positives = 114/326 (35%), Gaps = 36/326 (11%) Query 549 RCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRL 608 R S + P + F + LG+G VY + Sbjct 59 RPTNLTKTPASQVSRRSSYTTDPPSPLTGITGFRNYSLDDFEIGKALGKGKFGKVY--LV 116 Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHT 668 + + +G K ++ LV G ++ F + S + HT Sbjct 117 KDKKTGFVSALKCMEKKELVEG-------------------NVEKQFRREVEIQSNLRHT 157 Query 669 HLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK 728 ++ + G ++ EYV HG L LR ++ + Q++ AL YL K Sbjct 158 NVLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQK-RFTESTASSYIYQMSEALLYLHGK 216 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--REERVERIPWLAPECLPG 786 N++H ++ NILL + IK+SD G + A S R + +L PE + Sbjct 217 NIIHRDIKPENILL-------HFNDTIKISDFGWSVHAPSNRRSTLCGTMDYLPPEIVQ- 268 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK--EHFYQRQHRLPEPSCPQLATL 844 + +D W G + E G P + ++ + R+P A L Sbjct 269 -SRPYDKNVDVWSLGILMYEFLC-GAPPFEEPGGAQATYRRIVKLDLRIPPYVSADAADL 326 Query 845 TSQCLTYEPTQRPSFRTILRDLTRLQ 870 + LT +P +R + + + ++ Sbjct 327 IKRMLTLDPAKRFKLKDMHKHPWIVR 352 >sp|G7JIK2|SUNN_MEDTR Leucine-rich repeat receptor-like kinase protein SUNN OS=Medicago truncatula OX=3880 GN=SUNN PE=1 SV=2 Length=974 Score = 224 bits (570), Expect = 7e-59, Method: Composition-based stats. Identities = 73/323 (23%), Positives = 126/323 (39%), Gaps = 21/323 (7%) Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920 + + R + ++A + LK+ +G+G G V + Sbjct 649 IVTLHMMRKRKRHMAKAWKLTAFQKLEFRAEEVVECLKEENIIGKGGAGIVYRG-----S 703 Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 G VA+K L ++ G+K EI+ L + H +I++ G ++ L+ EY Sbjct 704 MANGTDVAIKRLVGQGSGRNDYGFKAEIETLGRIRHRNIMRLLGYVSNKDTN--LLLYEY 761 Query 981 VPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDND 1034 +P GSL ++L + A + +G+ YLH IHRD+ + N+LLD D Sbjct 762 MPNGSLGEWLHGAKGCHLSWEMRYKIAVEAAKGLCYLHHDCSPLIIHRDVKSNNILLDAD 821 Query 1035 RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYEL 1094 + DFGLAK + + + S + APE K SDV+SFGV L EL Sbjct 822 FEAHVADFGLAKFLYDPGASQSMSSIAGS-YGYIAPEYAYTLKVDEKSDVYSFGVVLLEL 880 Query 1095 LTHCDSSQSPPTKFLELIGIAQG------QMTVLRLTELLERGERLPRPDKCPCEVYHLM 1148 + ++++G Q + L + P ++++ Sbjct 881 IIGRKPVGE-FGDGVDIVGWINKTELELYQPSDKALVSAVVDPRLNGYPLTSVIYMFNIA 939 Query 1149 KNCWETEASFRPTFENLIPILKT 1171 C + RPT ++ +L Sbjct 940 MMCVKEMGPARPTMREVVHMLTN 962 Score = 188 bits (478), Expect = 2e-47, Method: Composition-based stats. Identities = 53/326 (16%), Positives = 92/326 (28%), Gaps = 47/326 (14%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPS 647 + + + +G+G VY G V +K L Sbjct 685 LKEENIIGKGGAGIVYRG-------------------------SMANGTDVAIKRLVGQG 719 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG-HV 706 F + ++ H ++ + G N+++ EY+ +G L WL +G H+ Sbjct 720 SGRNDYGFKAEIETLGRIRHRNIMRLLGYVSNKDTNLLLYEYMPNGSLGEWLHGAKGCHL 779 Query 707 PMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + +A + A L YL + ++H +V NILL ++D G+ Sbjct 780 SWEMRYKIAVEAAKGLCYLHHDCSPLIIHRDVKSNNILLD-------ADFEAHVADFGLA 832 Query 764 LGAL------SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 S ++APE + D + FG LLE+ G P Sbjct 833 KFLYDPGASQSMSSIAGSYGYIAPEYA--YTLKVDEKSDVYSFGVVLLELII-GRKP-VG 888 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 + E P L S + P I + Sbjct 889 EFGDGVDIVGWINKTELELYQPSDKALVSAVVDPRLNGYPLTSVIYMFNIAMMCVKEMGP 948 Query 878 LTVNPDSPASDPTVFHKRYLKKIRDL 903 T + +L Sbjct 949 ARPTMREVVHMLTNPPHSTSHNLINL 974 >sp|F4IS56|ILK1_ARATH Integrin-linked protein kinase 1 OS=Arabidopsis thaliana OX=3702 GN=ILK1 PE=1 SV=1 Length=479 Score = 214 bits (545), Expect = 7e-59, Method: Composition-based stats. Identities = 72/261 (28%), Positives = 115/261 (44%), Gaps = 22/261 (8%) Query 921 DGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978 G V+VK L D P+ + ++ E+ +L + H ++I++ G + +V+ Sbjct 213 KWNGTRVSVKILDKDSYSDPERINAFRHELTLLEKVRHPNVIQFVGAVTQN--IPMMIVV 270 Query 979 EYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDND 1034 EY P G L YL + + ++ L FA I GM YLH IH DL +N+LLD Sbjct 271 EYNPKGDLSVYLQKKGRLSPSKALRFALDIARGMNYLHECKPDPIIHCDLKPKNILLDRG 330 Query 1035 RLVKIGDFG---LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091 +KI FG L+K + + + D ++ APE K+ F D SFGV L Sbjct 331 GQLKISGFGMIRLSKISQDKAKVANHKAHIDLSNYYIAPEVYKDEIFDLRVDAHSFGVIL 390 Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 YE+ P + + + +G+ V + + P ++ L++ C Sbjct 391 YEITEGVPVFHPRPPEEVARMMCLEGKRPVFK-----------TKSRSYPPDIKELIEKC 439 Query 1152 WETEASFRPTFENLIPILKTV 1172 W EA RPTF +I L + Sbjct 440 WHPEAGIRPTFSEIIIRLDKI 460 Score = 173 bits (438), Expect = 7e-45, Method: Composition-based stats. Identities = 58/298 (19%), Positives = 105/298 (35%), Gaps = 35/298 (12%) Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH---DIALAFYETASLMSQVSHTH 669 + + + G RV +K+LD + + AF +L+ +V H + Sbjct 195 EVQVRKSDGISKGAYQVAKWNGT--RVSVKILDKDSYSDPERINAFRHELTLLEKVRHPN 252 Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN-- 727 + G + ++V EY G L V+L++ +G + + + A +A ++YL Sbjct 253 VIQFVGAVTQNIPMMIVVEYNPKGDLSVYLQK-KGRLSPSKALRFALDIARGMNYLHECK 311 Query 728 -KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGALSREERVERI---- 776 ++H ++ +NILL R G +K+S G+ I Sbjct 312 PDPIIHCDLKPKNILLDRGGQ-------LKISGFGMIRLSKISQDKAKVANHKAHIDLSN 364 Query 777 PWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP-- 834 ++APE +D FG L EI +G R P E + + P Sbjct 365 YYIAPEVYKDEI--FDLRVDAHSFGVILYEI-TEGVPVFHPRPPEEVARMMCLEGKRPVF 421 Query 835 ----EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASD 888 P + L +C E RP+F I+ L ++ + + Sbjct 422 KTKSRSYPPDIKELIEKCWHPEAGIRPTFSEIIIRLDKIVANCSKQGWWKDTFKFPWK 479 >sp|Q6XAT2|ERL2_ARATH LRR receptor-like serine/threonine-protein kinase ERL2 OS=Arabidopsis thaliana OX=3702 GN=ERL2 PE=1 SV=1 Length=967 Score = 224 bits (570), Expect = 7e-59, Method: Composition-based stats. Identities = 67/339 (20%), Positives = 128/339 (38%), Gaps = 20/339 (6%) Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 TL + + + + +L ++ D + L + Sbjct 595 FITLICMIFIAVYKSKQQKPVLKGSSKQPEGSTKLVILHMDMAIHTFDDIMRVTENLDEK 654 Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G G V T +A+K + + P + ++ E++ + ++ H +I+ Sbjct 655 YIIGYGASSTVYKCTSK-----TSRPIAIKRI-YNQYPSNFREFETELETIGSIRHRNIV 708 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHA 1016 G L +Y+ GSL D L + + L A +G+AYLH Sbjct 709 SLHGYALSPFGN--LLFYDYMENGSLWDLLHGPGKKVKLDWETRLKIAVGAAQGLAYLHH 766 Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 IHRD+ + N+LLD + ++ DFG+AK++P Y G + + PE Sbjct 767 DCTPRIIHRDIKSSNILLDGNFEARLSDFGIAKSIPATKTYASTYVLG--TIGYIDPEYA 824 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + + SD++SFG+ L ELLT + + ++I TV+ + Sbjct 825 RTSRLNEKSDIYSFGIVLLELLTGKKAVDN-EANLHQMILSKADDNTVMEAVDAEVSVTC 883 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + + + L C + RPT + + +L ++ Sbjct 884 MD--SGHIKKTFQLALLCTKRNPLERPTMQEVSRVLLSL 920 Score = 184 bits (466), Expect = 4e-46, Method: Composition-based stats. Identities = 51/341 (15%), Positives = 117/341 (34%), Gaps = 67/341 (20%) Query 555 PGETSNLIIMRGARASPR--------TLNLSQLSFHRVDQ--KEITQLSHLGQGTRTNVY 604 +++G+ P ++++ +F + + + + + +G G + VY Sbjct 607 YKSKQQKPVLKGSSKQPEGSTKLVILHMDMAIHTFDDIMRVTENLDEKYIIGYGASSTVY 666 Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664 + + + +K + + F + Sbjct 667 KCTSK-------------------------TSRPIAIKRIYNQYPSNFREFETELETIGS 701 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASAL 722 + H ++ +HG + N++ +Y+E+G L L V + W ++ +A A L Sbjct 702 IRHRNIVSLHGYALSPFGNLLFYDYMENGSLWDLLHGPGKKVKLDWETRLKIAVGAAQGL 761 Query 723 SYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV-----E 774 +YL + ++H ++ NILL + +LSD G+ + + Sbjct 762 AYLHHDCTPRIIHRDIKSSNILLD-------GNFEARLSDFGIAKSIPATKTYASTYVLG 814 Query 775 RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP 834 I ++ PE + L+ D + FG LLE+ +A + + + + Sbjct 815 TIGYIDPEYART--SRLNEKSDIYSFGIVLLELLTGKKAVDNEANLHQMILSKADDNTVM 872 Query 835 EPSCPQLA-------------TLTSQCLTYEPTQRPSFRTI 862 E +++ L C P +RP+ + + Sbjct 873 EAVDAEVSVTCMDSGHIKKTFQLALLCTKRNPLERPTMQEV 913 >sp|Q66HE7|CDKL1_RAT Cyclin-dependent kinase-like 1 OS=Rattus norvegicus OX=10116 GN=Cdkl1 PE=2 SV=1 Length=352 Score = 210 bits (534), Expect = 7e-59, Method: Composition-based stats. Identities = 62/293 (21%), Positives = 119/293 (41%), Gaps = 29/293 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWKQEIDILRTLYHEHII 960 +GEG +G V + N TG++VA+K L+ + P + +EI +L+ L H +++ Sbjct 9 KIGEGSYGVV----FKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLV 64 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + + L LV EY L + + + + Q + + + H + Sbjct 65 SLLEVFRRK--RRLHLVFEYCHHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKHNC 122 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL-KEYKF 1078 IHRD+ N+L+ ++K+ DFG A+ + +YY D + ++ +PE L + ++ Sbjct 123 IHRDVKPENILITKHSVIKLCDFGFARLLTGPGDYY---TDYVATRWYRSPELLVGDTQY 179 Query 1079 YYASDVWSFGVTLYELLTHCD-----SSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 DVW+ G ELL+ S + +G + + G + Sbjct 180 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVK 239 Query 1134 LPRPD----------KCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHE 1174 +P P+ +K C + + R T E L+ P ++ + Sbjct 240 IPDPEDMETLELKFPNISYSALGFLKGCLHMDPAERLTCEQLLQHPYFDSIRD 292 Score = 154 bits (389), Expect = 1e-39, Method: Composition-based stats. Identities = 49/250 (20%), Positives = 86/250 (34%), Gaps = 40/250 (16%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ ++ +G+G+ V++ R R G V +K Sbjct 1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQ------------------------IVAIKRFL 36 Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + D I ++ Q+ H +L + V R +V EY H L R +R Sbjct 37 ETEDDPVIKKIALREIRMLKQLKHPNLVSLLEVFRRKRRLHLVFEYCHHTVLHELDRYQR 96 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 G VP + Q A+++ N +H +V NIL+ + IKL D G Sbjct 97 G-VPEPLVKNITWQTLQAVNFCHKHNCIHRDVKPENILITK-------HSVIKLCDFGFA 148 Query 764 LGAL----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + V + +PE L G +D W G E+ G +S Sbjct 149 RLLTGPGDYYTDYVATRWYRSPELLV-GDTQYGPPVDVWAIGCVFAELLS-GVPLWPGKS 206 Query 820 PSEKEHFYQR 829 ++ + ++ Sbjct 207 DVDQLYLIRK 216 >sp|Q7RJG2|CDPK4_PLAYO Calcium-dependent protein kinase 4 OS=Plasmodium yoelii yoelii OX=73239 GN=CDPK4 PE=3 SV=3 Length=528 Score = 215 bits (548), Expect = 8e-59, Method: Composition-based stats. Identities = 69/288 (24%), Positives = 116/288 (40%), Gaps = 33/288 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960 LG+G FG+V L + TG A+K + + +E+++L+ L H +I+ Sbjct 76 LGKGSFGEVILS----KDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINIM 131 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 K ED LV + G L D + R +Q+ G+ Y+H + Sbjct 132 KLYEFFEDNN--YYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNV 189 Query 1020 IHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRDL N+LL D ++KI DFGL+ EY + +D ++ AP+ L Sbjct 190 VHRDLKPENILLETKNKEDMIIKIIDFGLSTHF----EYSKKMKDKIGTAYYIAPDVL-H 244 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + D+WS GV LY LL+ C + +L+ E + LP Sbjct 245 GTYDEKCDIWSCGVILYILLSGCPPFNG------------SNEYDILKKVETGKYTFDLP 292 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183 + K + L+K ++ R + + L+ + +V Sbjct 293 QFKKISDKAKDLIKKMLMYTSAVRISARD---ALEHEWIRLMTSKDNV 337 Score = 157 bits (396), Expect = 4e-39, Method: Composition-based stats. Identities = 64/409 (16%), Positives = 131/409 (32%), Gaps = 52/409 (13%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 + S I+ S + + + V ++ + LG+G+ V Sbjct 35 RSTSISKEIVKNSFNNSKLRPGMFIQNSNVVFNEQYKGIKILGKGSFGEV---------- 84 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA---LAFYETASLMSQVSHTHL 670 + +D+ +KV+ H + L+ + H ++ Sbjct 85 --------------ILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINI 130 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730 ++ +V++ G L + + + + +Q+ S ++Y+ N+ Sbjct 131 MKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVD-AARIIKQVLSGITYMHKNNV 189 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---WLAPECLPGG 787 VH ++ NILL IK+ D G+ ++ ++I ++AP+ L G Sbjct 190 VHRDLKPENILL---ETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIAPDVLHG- 245 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR---LPEP--SCPQLA 842 + D W G L I G P + + + LP+ + Sbjct 246 --TYDEKCDIWSCGVILY-ILLSGCPPFNGSNEYDILKKVETGKYTFDLPQFKKISDKAK 302 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902 L + L Y R S R L + +V P S + + +K+ Sbjct 303 DLIKKMLMYTSAVRISARDALEHEWIRLMTSKDNVNIDIPSLELSITNIKQFQSTQKLAQ 362 Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAV-KALKADCGPQHRSGWKQEIDI 950 + + T D T E+ + K + + Q + E+ I Sbjct 363 AAL-----LYMGSKLTTIDETKELTKIFKKMDKNGDGQLD---RNELII 403 >sp|C0LGW6|ERL1_ARATH LRR receptor-like serine/threonine-protein kinase ERL1 OS=Arabidopsis thaliana OX=3702 GN=ERL1 PE=1 SV=1 Length=966 Score = 223 bits (569), Expect = 8e-59, Method: Composition-based stats. Identities = 68/345 (20%), Positives = 133/345 (39%), Gaps = 24/345 (7%) Query 838 CPQLATLTSQCLTYEPTQRPSF--RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKR 895 C L +T C+ + + + + + + +L ++ D + Sbjct 587 CIVLGVITLLCMIFLAVYKSMQQKKILQGSSKQAEGLTKLVILHMDMAIHTFDDIMRVTE 646 Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 L + +G G V + +A+K L + P + ++ E++ + ++ Sbjct 647 NLNEKFIIGYGASSTVYKCALK-----SSRPIAIKRL-YNQYPHNLREFETELETIGSIR 700 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGM 1011 H +I+ G L +Y+ GSL D L + + L A +G+ Sbjct 701 HRNIVSLHGYALSPTGN--LLFYDYMENGSLWDLLHGSLKKVKLDWETRLKIAVGAAQGL 758 Query 1012 AYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 AYLH IHRD+ + N+LLD + + DFG+AK++P + G + + Sbjct 759 AYLHHDCTPRIIHRDIKSSNILLDENFEAHLSDFGIAKSIPASKTHASTYVLG--TIGYI 816 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE + + SD++SFG+ L ELLT + + ++ A + E + Sbjct 817 DPEYARTSRINEKSDIYSFGIVLLELLTGKKAVDNEANLHQLILSKADDNT----VMEAV 872 Query 1129 ERGERLPRPD-KCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 + + D + + L C + RPT + +L ++ Sbjct 873 DPEVTVTCMDLGHIRKTFQLALLCTKRNPLERPTMLEVSRVLLSL 917 Score = 187 bits (476), Expect = 3e-47, Method: Composition-based stats. Identities = 50/300 (17%), Positives = 102/300 (34%), Gaps = 57/300 (19%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + + + +G G + VY+ L+ + +K L Sbjct 645 TENLNEKFIIGYGASSTVYKCALKSSRP-------------------------IAIKRLY 679 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + F + + H ++ +HG + N++ +Y+E+G L L Sbjct 680 NQYPHNLREFETELETIGSIRHRNIVSLHGYALSPTGNLLFYDYMENGSLWDLLHGSLKK 739 Query 706 VPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 V + W ++ +A A L+YL + ++H ++ NILL + LSD Sbjct 740 VKLDWETRLKIAVGAAQGLAYLHHDCTPRIIHRDIKSSNILLDE-------NFEAHLSDF 792 Query 761 GVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ + + I ++ PE + ++ D + FG LLE+ +A Sbjct 793 GIAKSIPASKTHASTYVLGTIGYIDPEYART--SRINEKSDIYSFGIVLLELLTGKKAVD 850 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQL-------------ATLTSQCLTYEPTQRPSFRTI 862 + + + + E P++ L C P +RP+ + Sbjct 851 NEANLHQLILSKADDNTVMEAVDPEVTVTCMDLGHIRKTFQLALLCTKRNPLERPTMLEV 910 >sp|P62345|CDPK4_PLABA Calcium-dependent protein kinase 4 OS=Plasmodium berghei (strain Anka) OX=5823 GN=CDPK4 PE=1 SV=2 Length=528 Score = 215 bits (548), Expect = 8e-59, Method: Composition-based stats. Identities = 69/288 (24%), Positives = 116/288 (40%), Gaps = 33/288 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960 LG+G FG+V L + TG A+K + + +E+++L+ L H +I+ Sbjct 76 LGKGSFGEVILS----KDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINIM 131 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 K ED LV + G L D + R +Q+ G+ Y+H + Sbjct 132 KLYEFFEDNN--YYYLVSDVYSGGELFDEIISRKRFYEVDAARIIKQVLSGITYMHKNNV 189 Query 1020 IHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRDL N+LL D ++KI DFGL+ EY + +D ++ AP+ L Sbjct 190 VHRDLKPENILLETKNKEDMIIKIIDFGLSTHF----EYSKKMKDKIGTAYYIAPDVL-H 244 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + D+WS GV LY LL+ C + +L+ E + LP Sbjct 245 GTYDEKCDIWSCGVILYILLSGCPPFNG------------SNEYDILKKVETGKYTFDLP 292 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183 + K + L+K ++ R + + L+ + +V Sbjct 293 QFKKISDKAKDLIKKMLMYTSAVRISARD---ALEHEWIRLMTSKDNV 337 Score = 157 bits (396), Expect = 5e-39, Method: Composition-based stats. Identities = 64/409 (16%), Positives = 131/409 (32%), Gaps = 52/409 (13%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 + S I+ S + + + V ++ + LG+G+ V Sbjct 35 RSTSISKEIVKNSFNNSKLRPGMFIQNSNVVFNEQYKGIKILGKGSFGEV---------- 84 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA---LAFYETASLMSQVSHTHL 670 + +D+ +KV+ H + L+ + H ++ Sbjct 85 --------------ILSKDKHTGHEYAIKVISKKHVKRKTDKQSLLREVELLKMLDHINI 130 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNL 730 ++ +V++ G L + + + + +Q+ S ++Y+ N+ Sbjct 131 MKLYEFFEDNNYYYLVSDVYSGGELFDEIISRKRFYEVD-AARIIKQVLSGITYMHKNNV 189 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIP---WLAPECLPGG 787 VH ++ NILL IK+ D G+ ++ ++I ++AP+ L G Sbjct 190 VHRDLKPENILL---ETKNKEDMIIKIIDFGLSTHFEYSKKMKDKIGTAYYIAPDVLHG- 245 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR---LPEP--SCPQLA 842 + D W G L I G P + + + LP+ + Sbjct 246 --TYDEKCDIWSCGVILY-ILLSGCPPFNGSNEYDILKKVETGKYTFDLPQFKKISDKAK 302 Query 843 TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRD 902 L + L Y R S R L + +V P S + + +K+ Sbjct 303 DLIKKMLMYTSAVRISARDALEHEWIRLMTSKDNVNIDIPSLELSITNIKQFQSTQKLAQ 362 Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAV-KALKADCGPQHRSGWKQEIDI 950 + + T D T E+ + K + + Q + E+ I Sbjct 363 AAL-----LYMGSKLTTIDETKELTKIFKKMDKNGDGQLD---RNELII 403 >sp|P53778|MK12_HUMAN Mitogen-activated protein kinase 12 OS=Homo sapiens OX=9606 GN=MAPK12 PE=1 SV=3 Length=367 Score = 210 bits (535), Expect = 8e-59, Method: Composition-based stats. Identities = 63/302 (21%), Positives = 123/302 (41%), Gaps = 36/302 (12%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLY 955 + ++ +G G +G V + TG VA+K L + +E+ +L+ + Sbjct 27 YRDLQPVGSGAYGAVC----SAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMR 82 Query 956 HEHIIKYKGCCEDQ----GEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011 HE++I LVM ++ L + +G ++ Q+ +G+ Sbjct 83 HENVIGLLDVFTPDETLDDFTDFYLVMPFM-GTDLGKLMKHEKLGEDRIQFLVYQMLKGL 141 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 Y+HA IHRDL N+ ++ D +KI DFGLA+ Y V ++ APE Sbjct 142 RYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVV------TRWYRAPE 195 Query 1072 CLKEY-KFYYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGI 1114 + + ++ D+WS G + E++T + +PP +F++ + Sbjct 196 VILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQS 255 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTV 1172 + + + L E LE+ + +L++ +A R T + P +++ Sbjct 256 DEAKNYMKGLPE-LEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFESL 314 Query 1173 HE 1174 H+ Sbjct 315 HD 316 Score = 127 bits (318), Expect = 4e-30, Method: Composition-based stats. Identities = 35/219 (16%), Positives = 71/219 (32%), Gaps = 20/219 (9%) Query 632 DRGQELRVVLKVL-DPSHHDI-ALAFYETASLMSQVSHTHLAFVHGVCVRGPEN------ 683 D +V +K L P ++ A Y L+ + H ++ + V Sbjct 46 DGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDF 105 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLA 743 +V ++ L ++ E+ + + Q+ L Y+ ++H ++ N+ Sbjct 106 YLVMPFM-GTDLGKLMKHEK--LGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNL--- 159 Query 744 RLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL-APECLPGGANSLSTAMDKWGFGA 802 A +K+ D G+ A S W APE + + +D W G Sbjct 160 ----AVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMR-YTQTVDIWSVGC 214 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL 841 + E+ S + + + P +L Sbjct 215 IMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRL 253 >sp|Q4WHP3|STE20_ASPFU Serine/threonine-protein kinase ste20 OS=Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) OX=330879 GN=ste20 PE=3 SV=2 Length=815 Score = 221 bits (564), Expect = 8e-59, Method: Composition-based stats. Identities = 60/270 (22%), Positives = 113/270 (42%), Gaps = 23/270 (9%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 + +G+G G V Y GT VA+K + D P+ + EI +++ H Sbjct 534 YYNLNKIGQGASGGV----YTAYQHGTNNCVAIKQMNLDLQPK-KELIINEILVMKDSKH 588 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016 ++I+ + + L +VMEY+ GSL D + + + Q+ ++ G+ +LH+ Sbjct 589 KNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMTEGQIAAVCRETLNGLQHLHS 646 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + IHRD+ + N+LL D +K+ DFG + ++ R +W APE + Sbjct 647 KGVIHRDIKSDNILLSLDGNIKLTDFGFCAQI---NDSQNKRNTMVGTPYWMAPEVVTRK 703 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 ++ D+WS G+ E++ + + L IA ++ L R Sbjct 704 EYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLIATNGTPTIKDEHNLSPVFR--- 759 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + HL + + R + +L+ Sbjct 760 ------DFLHLA---LKVDPEKRASAHDLL 780 Score = 179 bits (453), Expect = 7e-45, Method: Composition-based stats. Identities = 64/351 (18%), Positives = 104/351 (30%), Gaps = 45/351 (13%) Query 535 GCLLRAGDDCFSLRRCCLPQP-GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLS 593 G A D +L+ QP R + A L + K L+ Sbjct 479 GHSQHANDHTTALQSPQKAQPVPAARPRQRARQSNAVDVRARLLAICTPGDPTKLYYNLN 538 Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 +GQG VY G V +K ++ Sbjct 539 KIGQGASGGVY------------------------TAYQHGTNNCVAIKQMNLDLQPKKE 574 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV 713 +M H ++ + G + +V EY+E G L + + Sbjct 575 LIINEILVMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVV--TFNIMTEGQIAA 632 Query 714 VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS----R 769 V ++ + L +L +K ++H ++ NILL+ IKL+D G R Sbjct 633 VCRETLNGLQHLHSKGVIHRDIKSDNILLS-------LDGNIKLTDFGFCAQINDSQNKR 685 Query 770 EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR 829 V W+APE + +D W G +E+ +GE P + SP + Sbjct 686 NTMVGTPYWMAPEVVT--RKEYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLIAT 742 Query 830 QHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 P L +P +R S +L L Sbjct 743 NGTPTIKDEHNLSPVFRDFLHLALKVDPEKRASAHDLLMHPFMSLCSPLTH 793 >sp|Q59W62|GIN4_CANAL Serine/threonine-protein kinase GIN4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=GIN4 PE=1 SV=1 Length=1349 Score = 226 bits (575), Expect = 9e-59, Method: Composition-based stats. Identities = 81/308 (26%), Positives = 127/308 (41%), Gaps = 36/308 (12%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 PH+ ++ + S ++ K + LG G G+V L T+ TG+ AV Sbjct 1 MPHSRQPSISSSIMSQSNHNHPQKIGPWKLGKTLGRGATGRVLL----ATHQTTGQKAAV 56 Query 930 KALKADCGPQHRSG---------WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 K + + ++EI I++ L H ++++ E K+L LV+EY Sbjct 57 KVVSKSELQDEETEKNGDGLPYGIEREIIIMKLLTHPNVLRLYDVWE--TSKALYLVLEY 114 Query 981 VPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKI 1039 V G L D L R + + + + +QI G AY HA HRDL N+LLD+ VK+ Sbjct 115 VEGGELFDLLVERGPLPEVEAIKYFRQIILGTAYCHALGICHRDLKPENLLLDSQLNVKL 174 Query 1040 GDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHC 1098 DFG+A G ++ E + APE + K+ ASDVWS GV L+ LLT Sbjct 175 ADFGMAALESNG----KLLETSCGSPHYAAPEIVSGLKYHGAASDVWSCGVILFALLTGR 230 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 + L ++ G D+ E L+ E + Sbjct 231 LPFDDE---------------NIRNLLLKVQAGNFEMPVDEVSREARDLIARMLEVDPMR 275 Query 1159 RPTFENLI 1166 R + E ++ Sbjct 276 RISTEKIL 283 Score = 164 bits (415), Expect = 1e-39, Method: Composition-based stats. Identities = 54/292 (18%), Positives = 92/292 (32%), Gaps = 49/292 (17%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 LG+G V + G + +KV+ S Sbjct 29 KLGKTLGRGATGRVLLATHQTTGQ------------------------KAAVKVVSKSEL 64 Query 650 DIALA----------FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 +M ++H ++ ++ V +V EYVE G L L Sbjct 65 QDEETEKNGDGLPYGIEREIIIMKLLTHPNVLRLYDVWETSKALYLVLEYVEGGELFDLL 124 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 ERG +P + +Q+ +Y + H ++ N+LL + +KL+D Sbjct 125 -VERGPLPEVEAIKYFRQIILGTAYCHALGICHRDLKPENLLLD-------SQLNVKLAD 176 Query 760 PGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 G+ + E + APE + G A D W G L + G P Sbjct 177 FGMAALESNGKLLETSCGSPHYAAPE-IVSGLKYHGAASDVWSCGVILFALL-TGRLPFD 234 Query 817 SRSPSE-KEHFYQRQHRLP-EPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 + +P + + L ++ L +P +R S ILR Sbjct 235 DENIRNLLLKVQAGNFEMPVDEVSREARDLIARMLEVDPMRRISTEKILRHP 286 >sp|Q9M0G7|MIK1_ARATH MDIS1-interacting receptor like kinase 1 OS=Arabidopsis thaliana OX=3702 GN=MIK1 PE=1 SV=1 Length=1013 Score = 224 bits (570), Expect = 9e-59, Method: Composition-based stats. Identities = 68/301 (23%), Positives = 126/301 (42%), Gaps = 27/301 (9%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL---KADCGPQHRSGWKQEIDILR 952 +K+ +G G G V Y + ++AVK L AD + E+++L Sbjct 698 CIKESNMIGMGATGIV----YKAEMSRSSTVLAVKKLWRSAADIEDGTTGDFVGEVNLLG 753 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQ 1006 L H +I++ G +K++ +V E++ G+L D + + + A Sbjct 754 KLRHRNIVRLLGFLY--NDKNMMIVYEFMLNGNLGDAIHGKNAAGRLLVDWVSRYNIALG 811 Query 1007 ICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 + G+AYLH IHRD+ + N+LLD + +I DFGLA+ + E + Sbjct 812 VAHGLAYLHHDCHPPVIHRDIKSNNILLDANLDARIADFGLARMMARKKETVSM---VAG 868 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM-TVL 1122 + APE K D++S+GV L ELLT + + ++++ + ++ + Sbjct 869 SYGYIAPEYGYTLKVDEKIDIYSYGVVLLELLTGRRPLEPEFGESVDIVEWVRRKIRDNI 928 Query 1123 RLTELLERGE---RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 L E L+ R + + V + C RP+ ++I +L + + Sbjct 929 SLEEALDPNVGNCRYVQEEMLL--VLQIALLCTTKLPKDRPSMRDVISMLGEAKPRRKSN 986 Query 1180 A 1180 + Sbjct 987 S 987 Score = 184 bits (466), Expect = 6e-46, Method: Composition-based stats. Identities = 53/311 (17%), Positives = 109/311 (35%), Gaps = 68/311 (22%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 I + + +G G VY+ + +K L S Sbjct 699 IKESNMIGMGATGIVYKA------------------------EMSRSSTVLAVKKLWRSA 734 Query 649 HDIAL----AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER- 703 DI F +L+ ++ H ++ + G ++V E++ +G L + + Sbjct 735 ADIEDGTTGDFVGEVNLLGKLRHRNIVRLLGFLYNDKNMMIVYEFMLNGNLGDAIHGKNA 794 Query 704 -GHVPMAW--KMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKL 757 G + + W + +A +A L+YL + ++H ++ NILL + ++ Sbjct 795 AGRLLVDWVSRYNIALGVAHGLAYLHHDCHPPVIHRDIKSNNILLD-------ANLDARI 847 Query 758 SDPGVGLGALSREERV----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 +D G+ ++E V ++APE G + +D + +G LLE+ G Sbjct 848 ADFGLARMMARKKETVSMVAGSYGYIAPEY--GYTLKVDEKIDIYSYGVVLLELL-TGRR 904 Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQ-------------------LATLTSQCLTYEPT 854 PL+ + + ++ + + + + C T P Sbjct 905 PLEPEFGESVDIVEWVRRKIRDNISLEEALDPNVGNCRYVQEEMLLVLQIALLCTTKLPK 964 Query 855 QRPSFRTILRD 865 RPS R ++ Sbjct 965 DRPSMRDVISM 975 >sp|P17157|PHO85_YEAST Cyclin-dependent protein kinase PHO85 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PHO85 PE=1 SV=2 Length=305 Score = 208 bits (529), Expect = 9e-59, Method: Composition-based stats. Identities = 62/292 (21%), Positives = 114/292 (39%), Gaps = 36/292 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG G + V Y N TG VA+K +K D S +EI +++ L HE+I++ Sbjct 12 KLGNGTYATV----YKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVR 67 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG-------LAQLLLFAQQICEGMAYL 1014 E L LV E++ L+ Y+ ++G L + F Q+ +G+A+ Sbjct 68 LYDVI--HTENKLTLVFEFMDN-DLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFC 124 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H +HRDL +N+L++ +K+GDFGLA+A +++ AP+ L Sbjct 125 HENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIP---VNTFSSEVVTLWYRAPDVLM 181 Query 1075 EYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTK-----FLELIGIA------------- 1115 + + + D+WS G L E++T + +++G Sbjct 182 GSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLPK 241 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 R L + + + + + + R + + + Sbjct 242 YNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALH 293 Score = 170 bits (430), Expect = 1e-45, Method: Composition-based stats. Identities = 47/268 (18%), Positives = 95/268 (35%), Gaps = 43/268 (16%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + QL LG GT VY+G + G + V LK + Sbjct 5 SQFKQLEKLGNGTYATVYKGLNKTTG------------------------VYVALKEVKL 40 Query 647 SHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE--- 702 + SLM ++ H ++ ++ V + +V E++++ L ++ Sbjct 41 DSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDN-DLKKYMDSRTVG 99 Query 703 --RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + + QL L++ ++H ++ +N+L+ + G +KL D Sbjct 100 NTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRG-------QLKLGDF 152 Query 761 GVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 G+ + V + + AP+ L G+ + ST++D W G L E+ Sbjct 153 GLARAFGIPVNTFSSEVVTLWYRAPDVLM-GSRTYSTSIDIWSCGCILAEMITGKPLFPG 211 Query 817 SRSPSEKEHFYQRQHRLPEPSCPQLATL 844 + + + + E P + L Sbjct 212 TNDEEQLKLIFDIMGTPNESLWPSVTKL 239 >sp|Q9C5H5|M3K5G_ARATH Mitogen-activated protein kinase kinase kinase 5 OS=Arabidopsis thaliana OX=3702 GN=MAPKKK5 PE=1 SV=1 Length=716 Score = 219 bits (559), Expect = 1e-58, Method: Composition-based stats. Identities = 86/367 (23%), Positives = 143/367 (39%), Gaps = 49/367 (13%) Query 833 LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVF 892 L + C P P T + + +P +P + Sbjct 291 LHPRLSTDVTNGRRDCCNVHPLPLPPGAT---------CSSSSAASVPSPQAPLKLDSFP 341 Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD----CGPQHRSGWKQEI 948 KK + +G G FG V Y +N TG + A+K ++ + +QEI Sbjct 342 MNSQWKKGKLIGRGTFGSV----YVASNSETGALCAMKEVELFPDDPKSAECIKQLEQEI 397 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQ 1006 +L L H +I++Y G + E + +EYV GS+ Y+ H ++ + + F + Sbjct 398 KLLSNLQHPNIVQYFGS--ETVEDRFFIYLEYVHPGSINKYIRDHCGTMTESVVRNFTRH 455 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I G+AYLH + +HRD+ N+L+D +VK+ DFG+AK + R + Sbjct 456 ILSGLAYLHNKKTVHRDIKGANLLVDASGVVKLADFGMAKHL----TGQRADLSLKGSPY 511 Query 1067 WYAPECLK-------EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM 1119 W APE ++ +A D+WS G T+ E+ T PP E M Sbjct 512 WMAPELMQAVMQKDSNPDLAFAVDIWSLGCTIIEMFTGK-----PPWSEFEGAAAMFKVM 566 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQ 1179 + P P+ E ++ C++ + RPT L+ + + Q Sbjct 567 -----------RDSPPIPESMSPEGKDFLRLCFQRNPAERPTASMLLEH-RFLKNSLQPT 614 Query 1180 APSVFSV 1186 +PS V Sbjct 615 SPSNSDV 621 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 68/377 (18%), Positives = 123/377 (33%), Gaps = 38/377 (10%) Query 539 RAGDDCFSLRR-CCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK-EITQLSHLG 596 R D + RR CC P + A+ + L + + +G Sbjct 294 RLSTDVTNGRRDCCNVHPLPLPPGATCSSSSAASVPSPQAPLKLDSFPMNSQWKKGKLIG 353 Query 597 QGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFY 656 +GT +VY G+ + D DP + Sbjct 354 RGTFGSVYVASNSETGALCAMKEVELFPD-------------------DPKSAECIKQLE 394 Query 657 ETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 + L+S + H ++ G + EYV G ++ ++R G + + + Sbjct 395 QEIKLLSNLQHPNIVQYFGSETVEDRFFIYLEYVHPGSINKYIRDHCGTMTESVVRNFTR 454 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL---GALSREERV 773 + S L+YL NK VH ++ G N+L+ G+ +KL+D G+ G + Sbjct 455 HILSGLAYLHNKKTVHRDIKGANLLVDASGV-------VKLADFGMAKHLTGQRADLSLK 507 Query 774 ERIPWLAPECLPGGANSLST-----AMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 W+APE + S A+D W G T++E+ F G+ P + Sbjct 508 GSPYWMAPELMQAVMQKDSNPDLAFAVDIWSLGCTIIEM-FTGKPPWSEFEGAAAMFKVM 566 Query 829 RQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPAS 887 R +PE P+ C P +RP+ +L + + Sbjct 567 RDSPPIPESMSPEGKDFLRLCFQRNPAERPTASMLLEHRFLKNSLQPTSPSNSDVSQLFN 626 Query 888 DPTVFHKRYLKKIRDLG 904 + ++ + Sbjct 627 GMNITEPSSRREKPNFK 643 >sp|G4NDR3|MCK1_PYRO7 Mitogen-activated protein kinase kinae kinase MCK1 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507 GN=MCK1 PE=1 SV=1 Length=1528 Score = 226 bits (575), Expect = 1e-58, Method: Composition-based stats. Identities = 78/338 (23%), Positives = 131/338 (39%), Gaps = 38/338 (11%) Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGE 905 S L + T+ + + R S P K + +G+ Sbjct 1187 SALLRRKSTKMFNANIVQIRPNRDSMLVPDIPQDSISSSSRGAPKHPTTFRWFKGQLIGK 1246 Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKAL---------KADCGPQHRSGWKQEIDILRTLYH 956 G +G+V L N TGE +AVK + + + QEI+ ++ L H Sbjct 1247 GTYGRVYLGM----NATTGEFLAVKEVEVNPRAAAGDKKRMKELVAALDQEIETMQHLDH 1302 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLH 1015 +I++Y GC ++ E S+ + +EY+ GS+ L ++ + + +Q G+AYLH Sbjct 1303 VNIVQYLGC--ERKETSISIFLEYISGGSIGSCLRKNGKFEESVVQSLTRQTLSGLAYLH 1360 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK- 1074 + +HRDL A N+LLD D KI DFG++K + VFW APE ++ Sbjct 1361 REGILHRDLKADNILLDVDGTAKISDFGISKK-TDNIYGNDKSNSMQGSVFWMAPEVIRS 1419 Query 1075 -EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + D+WS G + E+ + + + GE Sbjct 1420 QGEGYSAKVDIWSLGCVVLEMFAGRRP---------------WAKEEAVGAIYKIANGEI 1464 Query 1134 LPRPDK----CPCEVYHLMKNCWETEASFRPTFENLIP 1167 P P+ M +C+ ++ RPT L+ Sbjct 1465 PPIPEDVQDTISPIAVAFMMDCFTVDSHDRPTANKLLS 1502 Score = 196 bits (498), Expect = 2e-49, Method: Composition-based stats. Identities = 57/292 (20%), Positives = 96/292 (33%), Gaps = 35/292 (12%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + +G+GT VY G G + + + R +EL L Sbjct 1240 KGQLIGKGTYGRVYLGMNATTGEFLAVKEVEVNPRAAAGDKKRMKELVAAL--------- 1290 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 + M + H ++ G + + EY+ G + LR+ G + Sbjct 1291 -----DQEIETMQHLDHVNIVQYLGCERKETSISIFLEYISGGSIGSCLRKN-GKFEESV 1344 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL------ 764 + +Q S L+YL + ++H ++ NILL G A K+SD G+ Sbjct 1345 VQSLTRQTLSGLAYLHREGILHRDLKADNILLDVDGTA-------KISDFGISKKTDNIY 1397 Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 G + W+APE + S +D W G +LE+ F G P Sbjct 1398 GNDKSNSMQGSVFWMAPEVIRSQGEGYSAKVDIWSLGCVVLEM-FAGRRPWAKEEAVGAI 1456 Query 825 HFYQRQHRLP------EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 + P + P C T + RP+ +L + Sbjct 1457 YKIANGEIPPIPEDVQDTISPIAVAFMMDCFTVDSHDRPTANKLLSQHPFCE 1508 >sp|P39951|CDK1_RAT Cyclin-dependent kinase 1 OS=Rattus norvegicus OX=10116 GN=Cdk1 PE=1 SV=1 Length=297 Score = 207 bits (527), Expect = 1e-58, Method: Composition-based stats. Identities = 66/307 (21%), Positives = 124/307 (40%), Gaps = 38/307 (12%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ Sbjct 1 MEDYIKIEKIGEGTYGVV----YKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQIC 1008 L H +I+ + + L L+ E++ + L+ YL P + + + + QI Sbjct 57 ELRHPNIVSLQDVLMQ--DSRLYLIFEFLSM-DLKKYLDSIPPGQFMDSSLVKSYLYQIL 113 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +G+ + H++ +HRDL +N+L+D+ +K+ DFGLA+A RV +++ Sbjct 114 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP---IRVYTHEVVTLWYR 170 Query 1069 APECLKEY-KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 +PE L ++ D+WS G EL T + Sbjct 171 SPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPE 230 Query 1128 LE--RGERLPRPDKCPCEVY-----------HLMKNCWETEASFR---------PTFENL 1165 +E + + P P + L+ + + R P F++L Sbjct 231 VESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDL 290 Query 1166 IPILKTV 1172 +K + Sbjct 291 DNQIKKM 297 Score = 164 bits (415), Expect = 1e-43, Method: Composition-based stats. Identities = 42/267 (16%), Positives = 93/267 (35%), Gaps = 41/267 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ ++ +G+GT VY+GR R G V +K + Sbjct 1 MEDYIKIEKIGEGTYGVVYKGRHRTTGQ------------------------IVAMKKIR 36 Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702 + + SL+ ++ H ++ + V ++ ++ E++ L +L Sbjct 37 LESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95 Query 703 RGHV-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 G + Q+ + + ++ ++H ++ +N+L+ G IKL+D G Sbjct 96 PGQFMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKG-------TIKLADFG 148 Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + V + + +PE L G+ ST +D W G E+ Sbjct 149 LARAFGIPIRVYTHEVVTLWYRSPEVLL-GSARYSTPVDIWSIGTIFAELATKKPLFHGD 207 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ P++ +L Sbjct 208 SEIDQLFRIFRALGTPNNEVWPEVESL 234 >sp|Q9FN93|Y5596_ARATH Probable LRR receptor-like serine/threonine-protein kinase At5g59680 OS=Arabidopsis thaliana OX=3702 GN=At5g59680 PE=1 SV=1 Length=887 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 63/254 (25%), Positives = 114/254 (45%), Gaps = 12/254 (5%) Query 925 EMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLG 984 E VAVK L + Q +K E+D+L ++H +++ G C++ L L+ E+VP G Sbjct 603 EQVAVK-LLSQSSTQGYKEFKAEVDLLLRVHHTNLVSLVGYCDEGDH--LALIYEFVPNG 659 Query 985 SLRDYLPRHS----IGLAQLLLFAQQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLV 1037 LR +L + L A + G+ YLH +HRD+ N+LLD Sbjct 660 DLRQHLSGKGGKPIVNWGTRLRIAAEAALGLEYLHIGCTPPMVHRDVKTTNILLDEHYKA 719 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTH 1097 K+ DFGL+++ P G E + +P + PE + SDV+SFG+ L E++T+ Sbjct 720 KLADFGLSRSFPVGGESHVSTVIAGTP-GYLDPEYYHTSRLSEKSDVYSFGIVLLEMITN 778 Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157 + + + ++ + ++++ + L +C + ++ Sbjct 779 -QAVIDRNRRKSHITQWVGSELNGGDIAKIMDLKLNGDYDSRSAWRALELAMSCADPTSA 837 Query 1158 FRPTFENLIPILKT 1171 RPT +++ LK Sbjct 838 RRPTMSHVVIELKE 851 Score = 191 bits (484), Expect = 2e-48, Method: Composition-based stats. Identities = 48/193 (25%), Positives = 77/193 (40%), Gaps = 20/193 (10%) Query 638 RVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDV 697 +V +K+L S F L+ +V HT+L + G C G ++ E+V +G L Sbjct 604 QVAVKLLSQSSTQGYKEFKAEVDLLLRVHHTNLVSLVGYCDEGDHLALIYEFVPNGDLRQ 663 Query 698 WLRRERGHVPMAW--KMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTS 752 L + G + W ++ +A + A L YL +VH +V NILL Sbjct 664 HLSGKGGKPIVNWGTRLRIAAEAALGLEYLHIGCTPPMVHRDVKTTNILLDE-------H 716 Query 753 PFIKLSDPGVGLG------ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 KL+D G+ + +L PE + LS D + FG LLE Sbjct 717 YKAKLADFGLSRSFPVGGESHVSTVIAGTPGYLDPEYYHT--SRLSEKSDVYSFGIVLLE 774 Query 807 ICFDGEAPLQSRS 819 + + ++R Sbjct 775 MITNQAVIDRNRR 787 >sp|Q8BZN4|NUAK2_MOUSE NUAK family SNF1-like kinase 2 OS=Mus musculus OX=10090 GN=Nuak2 PE=1 SV=2 Length=639 Score = 218 bits (554), Expect = 1e-58, Method: Composition-based stats. Identities = 67/297 (23%), Positives = 113/297 (38%), Gaps = 36/297 (12%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP 938 + + + LG+G +GKV + +G +VA+K+++ D Sbjct 39 MKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKAR-----ESSGRLVAIKSIRKDKIK 93 Query 939 QHRS--GWKQEIDILRTLYHEHIIKYKGCCEDQ------GEKSLQLVMEYVPLGSLRDYL 990 + ++EI+I+ +L H HII + + +VMEY G L DY+ Sbjct 94 DEQDLLHIRREIEIMSSLNHPHIIAIHEVGRSRLVTVFENSSKIVIVMEYASRGDLYDYI 153 Query 991 -PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP 1049 R + F +QI + Y H +HRDL N+LLD + +KI DFGL+ Sbjct 154 SERPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNLYH 213 Query 1050 EGHEYYRVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 +G + + + +PE + + D WS GV LY L+ K Sbjct 214 KG----KFLQTFCGSPLYASPEIVNGKPYVGPEVDSWSLGVLLYILVHGTMPFDGQDHKT 269 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L + + G P P + L++ + R T E++ Sbjct 270 ---------------LVKQISNGAYREPPK--PSDACGLIRWLLMVNPTRRATLEDV 309 Score = 170 bits (430), Expect = 1e-42, Method: Composition-based stats. Identities = 52/292 (18%), Positives = 86/292 (29%), Gaps = 49/292 (17%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 L LG+GT V + R V +K + Sbjct 58 EFLETLGKGTYGKVKKAR-------------------------ESSGRLVAIKSIRKDKI 92 Query 650 DIALAFY---ETASLMSQVSHTHLA--------FVHGVCVRGPENIMVTEYVEHGPLDVW 698 +MS ++H H+ + V + ++V EY G L + Sbjct 93 KDEQDLLHIRREIEIMSSLNHPHIIAIHEVGRSRLVTVFENSSKIVIVMEYASRGDLYDY 152 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 + ER + +Q+ SAL Y +VH ++ NILL + IK++ Sbjct 153 I-SERPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLD-------ANGNIKIA 204 Query 759 DPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 D G+ + + +PE + G + +D W G L I G P Sbjct 205 DFGLSNLYHKGKFLQTFCGSPLYASPEIVNGKPY-VGPEVDSWSLGVLLY-ILVHGTMPF 262 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + P L L PT+R + + Sbjct 263 DGQDHKTLVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASHWW 314 >sp|Q8WNU8|NEK11_MACFA Serine/threonine-protein kinase Nek11 OS=Macaca fascicularis OX=9541 GN=NEK11 PE=2 SV=1 Length=637 Score = 218 bits (554), Expect = 1e-58, Method: Composition-based stats. Identities = 64/306 (21%), Positives = 117/306 (38%), Gaps = 28/306 (9%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 + A + ++ P R + LG G FG V L G V Sbjct 1 MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKV- 59 Query 929 VKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLR 987 +K + + P E +L L H I+K+ +Q + ++ EY L Sbjct 60 LKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQD--NFCIITEYCEGRDLD 117 Query 988 DYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDF 1042 + + Q++ + Q+ G+ Y+H + +HRDL ++N+ L N+ +KIGDF Sbjct 118 YKIQEYKEAGKIFPDNQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNNL-LKIGDF 176 Query 1043 GLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ 1102 G+++ + + + +PE LK + SD+WS LYE+ Sbjct 177 GVSRLLMGSCDLATTLT---GTPHYMSPEALKHQGYDTKSDIWSLACILYEMC------- 226 Query 1103 SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTF 1162 + A L + + G+ P++ P E+ +M++ S RP+ Sbjct 227 --------CMNHAFAGSNFLSIVLKIVEGDTPSLPERYPKELNTIMESMLNKNPSLRPSA 278 Query 1163 ENLIPI 1168 ++ I Sbjct 279 IEILKI 284 Score = 176 bits (447), Expect = 8e-45, Method: Composition-based stats. Identities = 70/384 (18%), Positives = 114/384 (30%), Gaps = 54/384 (14%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LG G+ VY RG+EL+V LK + + Sbjct 34 KLGSGSFGTVYL--------------------VSDKKAKRGEELKV-LKEISVGELNPNE 72 Query 654 AFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER---GHVPM 708 A L+S++ H + H V ++TEY E LD ++ + P Sbjct 73 TVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDYKIQEYKEAGKIFPD 132 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 + QL + Y+ + ++H ++ +NI L L K+ D GV + Sbjct 133 NQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNNLL--------KIGDFGVSRLLMG 184 Query 769 R----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 +++PE L T D W L E+C A S S Sbjct 185 SCDLATTLTGTPHYMSPEALKH--QGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVL 242 Query 825 HFYQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRP------SFRTILRDLTRLQPHNLADV 877 + LPE +L T+ L P+ RP I L L + Sbjct 243 KIVEGDTPSLPERYPKELNTIMESMLNKNPSLRPSAIEILKIPYIDEQLQHLMCRHSEMT 302 Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA---VKALKA 934 L + K+I +V A + LK Sbjct 303 LEDKNLDCQKEAARLINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADERARKLKK 362 Query 935 DCGPQHRSGWKQEIDILRTLYHEH 958 ++ K+ ++ L + Sbjct 363 IVEEKYEENSKR----MQELRSRN 382 >sp|Q8IBS5|CDPK4_PLAF7 Calcium-dependent protein kinase 4 OS=Plasmodium falciparum (isolate 3D7) OX=36329 GN=CDPK4 PE=1 SV=3 Length=528 Score = 214 bits (546), Expect = 1e-58, Method: Composition-based stats. Identities = 68/272 (25%), Positives = 112/272 (41%), Gaps = 30/272 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960 LG+G FG+V L + TG A+K + + +E+++L+ L H +I+ Sbjct 76 LGKGSFGEVILS----RDKHTGHEYAIKVISKKHVKRKTDKESLLREVELLKMLDHINIM 131 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 K ED LV + G L D + R +QI G+ Y+H + Sbjct 132 KLYEFFEDNN--YYYLVSDVYTGGELFDEIISRKRFYEIDAARIIKQILSGITYMHKNNV 189 Query 1020 IHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRDL N+LL D ++KI DFGL+ EY + +D ++ AP+ L Sbjct 190 VHRDLKPENILLETKNKEDMIIKIIDFGLSTHF----EYSKKMKDKIGTAYYIAPDVL-H 244 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + D+WS GV LY LL+ C + +L+ E + LP Sbjct 245 GTYDEKCDIWSCGVILYILLSGCPPFNG------------SNEYDILKKVEAGKYTFDLP 292 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + K + L+K ++ R + + + Sbjct 293 QFKKISDKAKDLIKKMLMYTSAVRISARDALE 324 Score = 156 bits (394), Expect = 1e-38, Method: Composition-based stats. Identities = 60/377 (16%), Positives = 122/377 (32%), Gaps = 52/377 (14%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ + LG+G+ V + RD+ +KV+ Sbjct 67 NEQYKGIKILGKGSFGEV------------------------ILSRDKHTGHEYAIKVIS 102 Query 646 PSHHDIA---LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 H + L+ + H ++ ++ +V++ G L + Sbjct 103 KKHVKRKTDKESLLREVELLKMLDHINIMKLYEFFEDNNYYYLVSDVYTGGELFDEIISR 162 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + + + +Q+ S ++Y+ N+VH ++ NILL IK+ D G+ Sbjct 163 KRFYEID-AARIIKQILSGITYMHKNNVVHRDLKPENILL---ETKNKEDMIIKIIDFGL 218 Query 763 GLGALSREERVERIP---WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 ++ ++I ++AP+ L G + D W G L I G P + Sbjct 219 STHFEYSKKMKDKIGTAYYIAPDVLHG---TYDEKCDIWSCGVILY-ILLSGCPPFNGSN 274 Query 820 PSEKEHFYQRQHR---LPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNL 874 + + LP+ + L + L Y R S R L + Sbjct 275 EYDILKKVEAGKYTFDLPQFKKISDKAKDLIKKMLMYTSAVRISARDALEHEWIKMMTSK 334 Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV-KALK 933 ++ P S + + +K+ + + T D T E+ + K + Sbjct 335 DNLNIDIPSLELSIANIRQFQSTQKLAQAAL-----LYMGSKLTTIDETKELTKIFKKMD 389 Query 934 ADCGPQHRSGWKQEIDI 950 + Q + E+ I Sbjct 390 KNGDGQLD---RNELII 403 >sp|Q54HC6|ARKA_DICDI Ankyrin repeat-containing protein kinase A OS=Dictyostelium discoideum OX=44689 GN=arkA PE=1 SV=1 Length=1460 Score = 225 bits (574), Expect = 1e-58, Method: Composition-based stats. Identities = 70/284 (25%), Positives = 122/284 (43%), Gaps = 15/284 (5%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 +G G GKV Y G +VA+K LK+ R + +E +L +L Sbjct 1114 YTEKIGSGASGKVFKGIYR------GRVVAIKVLKSADDEMTREDFLKEFGVLASLESHT 1167 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQ- 1017 I+ G E + LVMEY GS+ + ++ + F QQ+ G+ LH Sbjct 1168 IVGLYGVVL---EPKICLVMEYCSNGSIYHSIRKNPPSWERFFSFVQQMLAGINALHQST 1224 Query 1018 -HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRD+ N L++++ VK+ DFGL++ E ++ + G S + APE + Sbjct 1225 PQVLHRDIKTLNFLVNHNNKVKVADFGLSRFNTESNQETLNKTRGTSV--YCAPEVFEGK 1282 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 ++ SD++S G+ ++E++ +C + E + L L +R R Sbjct 1283 EYNERSDMYSMGIVMWEIV-YCVVYGCYMIPYQEYNKMFNAFQVAL-LVNSSKRVLRPTI 1340 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180 P P + L+ W+ + S RPT + L ++Y+ Sbjct 1341 PIGVPQVLKDLIYCLWDHDVSSRPTATEAMTALAVCEKEYKQNK 1384 Score = 156 bits (395), Expect = 4e-37, Method: Composition-based stats. Identities = 59/414 (14%), Positives = 124/414 (30%), Gaps = 80/414 (19%) Query 485 LTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAALQGCLL--RAGD 542 L +A + L R I + LE + S + LQ + R + Sbjct 998 LALAVDYDVCPEISDLLRRLDTITTSLEMYELEKFQASL-----VVEELQKENVVARLDE 1052 Query 543 DCFSLRRCCLPQPGET-----SNLIIMRG-ARASPRTLNLSQLSFHRVDQ-------KEI 589 C + SN +++ AR + L ++ + E+ Sbjct 1053 KLLDKIGCTDKEERRKFLSLKSNRLLIHHPARTQGAKIILKEMETMDIKNGKLIISETEL 1112 Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 +G G V++G R V +KVL + Sbjct 1113 EYTEKIGSGASGKVFKGIYRGR--------------------------VVAIKVLKSADD 1146 Query 650 DIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 ++ F + +++ + + ++GV + P+ +V EY +G + +R+ Sbjct 1147 EMTREDFLKEFGVLASLESHTIVGLYGVVLE-PKICLVMEYCSNGSIYHSIRKN--PPSW 1203 Query 709 AWKMVVAQQLASALSYLENK--NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 QQ+ + ++ L ++H ++ N L+ + +K++D G+ Sbjct 1204 ERFFSFVQQMLAGINALHQSTPQVLHRDIKTLNFLVNH-------NNKVKVADFGLSRFN 1256 Query 767 LSR-----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + + APE G + D + G + EI + Sbjct 1257 TESNQETLNKTRGTSVYCAPEVFEG--KEYNERSDMYSMGIVMWEIVYCVVYGCYMIPYQ 1314 Query 822 EKEHFYQR--------------QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861 E + + +P L L ++ + RP+ Sbjct 1315 EYNKMFNAFQVALLVNSSKRVLRPTIPIGVPQVLKDLIYCLWDHDVSSRPTATE 1368 >sp|Q7YRC6|AURKB_BOVIN Aurora kinase B OS=Bos taurus OX=9913 GN=AURKB PE=2 SV=1 Length=344 Score = 209 bits (531), Expect = 1e-58, Method: Composition-based stats. Identities = 73/330 (22%), Positives = 123/330 (37%), Gaps = 30/330 (9%) Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898 P L TL + L EP + + R + V+ + +P F + Sbjct 19 PGLNTLPQRVLRKEPVTPSALVLMSRSNAQPTAAPGQKVVENSSGTPNIPKRSFTIDDFE 78 Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYH 956 R LG+G FG V L + +VA+K L + ++EI+I L H Sbjct 79 IGRPLGKGKFGNVYL----AREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLQH 134 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLH 1015 +I++ D+ + + L++EY P G L L + + + +++ + + Y H Sbjct 135 PNILRLYNYFYDR--RRIYLILEYAPRGELYKELQKSRTFDEQRTATIMEELADALTYCH 192 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 A+ IHRD+ N+LL +KI DFG + P R+ + + PE ++ Sbjct 193 AKKVIHRDIKPENLLLGLRGELKIADFGWSVHAPSLR-----RKTMCGTLDYLPPEMIEG 247 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 D+W GV YELL +S A T R+ ++ L Sbjct 248 RTHNEKVDLWCIGVLCYELLVGNPPFES-----------ASHNETYRRIVKVD-----LK 291 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P P + + S R + Sbjct 292 FPPSVPLGAQDFIYKLLKHNPSERLPLAQV 321 Score = 177 bits (450), Expect = 8e-48, Method: Composition-based stats. Identities = 65/351 (19%), Positives = 117/351 (33%), Gaps = 50/351 (14%) Query 530 GAALQGCLLR---AGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQ 586 L +LR L QP ++ S T N+ + SF Sbjct 21 LNTLPQRVLRKEPVTPSALVLMSRSNAQPTAAPGQKVVE---NSSGTPNIPKRSFTI--- 74 Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + LG+G NVY R++ V LKVL Sbjct 75 DDFEIGRPLGKGKFGNVYLA------------------------REKKSHFIVALKVLFK 110 Query 647 SHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 S + + + + + H ++ ++ ++ EY G L L++ R Sbjct 111 SQIEKEGVEHQLRREIEIQAHLQHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSR 170 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + ++LA AL+Y K ++H ++ N+LL G +K++D G Sbjct 171 -TFDEQRTATIMEELADALTYCHAKKVIHRDIKPENLLL-------GLRGELKIADFGWS 222 Query 764 LGALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + A S R+ + +L PE + G + + +D W G E+ G P +S S + Sbjct 223 VHAPSLRRKTMCGTLDYLPPEMIEG--RTHNEKVDLWCIGVLCYELLV-GNPPFESASHN 279 Query 822 EK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 E + + P + L + P++R + Sbjct 280 ETYRRIVKVDLKFPPSVPLGAQDFIYKLLKHNPSERLPLAQVSAHPWVRTH 330 >sp|F4I3V3|LRL15_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 1.5 OS=Arabidopsis thaliana OX=3702 GN=LRK10L-1.5 PE=3 SV=1 Length=636 Score = 217 bits (553), Expect = 1e-58, Method: Composition-based stats. Identities = 76/359 (21%), Positives = 134/359 (37%), Gaps = 37/359 (10%) Query 855 QRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLY 914 + +I + + P + R +G+G FG V L Sbjct 282 RASFLSSINEEDPAALFLRHHRSAALLPPVFTFEELESATNKFDPKRKIGDGGFGSVYLG 341 Query 915 CYDPTNDGTGEMVAVKALK----------ADCGPQHRSGWKQEIDILRTLYHEHIIKYKG 964 G+++AVK L C + EI IL ++ H +++K G Sbjct 342 QL-----SDGQLLAVKFLHHHHGATAAATEHCKAFSMKSFCNEILILSSINHPNLVKLHG 396 Query 965 CCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHA---QHY 1019 C D + L LV +YV G+L D+L + L A Q M YLH Sbjct 397 YCSDP--RGLLLVHDYVTNGTLADHLHGRGPKMTWRVRLDIALQTALAMEYLHFDIVPPV 454 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGD-------SPVFWYAPEC 1072 +HRD+ + N+ ++ D +K+GDFGL++ + D + P+ Sbjct 455 VHRDITSSNIFVEKDMKIKVGDFGLSRLLVFSETTVNSATSSDYVCTGPQGTPGYLDPDY 514 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 + ++ SDV+S+GV L EL+T + Q + + L + ++ + L ++++ Sbjct 515 HRSFRLTEKSDVYSYGVVLMELITGMKAVDQRREKRDMALADLVVSKIQMGLLDQVIDPL 574 Query 1132 ERLPRPDKCP-------CEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183 L D V L C T+ RP + ++ L+ + + V Sbjct 575 LALDGDDVAAVSDGFGVAAVAELAFRCVATDKDDRPDAKEIVQELRRIRSHTRVADDDV 633 Score = 182 bits (461), Expect = 1e-46, Method: Composition-based stats. Identities = 72/418 (17%), Positives = 125/418 (30%), Gaps = 57/418 (14%) Query 440 PPRLVMSIRDGIHGPLLEPFVQAKLRPEDGLYLIH-------WSTSHPYRLILTVAQRSQ 492 P R++ HG L E Q L + + PY + Q Sbjct 160 PGRILHGCES-THGSLSEQGCQGDLLGFLQDFFTRFGFEVEWDESQDPYFIKCRDCQIKN 218 Query 493 APDGMQSLRLRKFPIEQQDGAFVLEGWGRS-----FPSVRELGAALQGCLLR--AGDDCF 545 G S + I L + +V L AL LL F Sbjct 219 GVCGFNSTHPNQDFICFHKSRSELVTQRDNNKRVNHIAVLSLIFALTCLLLVFSVAVAIF 278 Query 546 SLRRCCLPQPGETSN--LIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603 RR + + +R R++ + + +G G +V Sbjct 279 RSRRASFLSSINEEDPAALFLRHHRSAALLPPVFTFEELESATNKFDPKRKIGDGGFGSV 338 Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663 Y G+L + K +F ++S Sbjct 339 YLGQLSDGQLLAVKFLHHHHGATAAATEH--------CKAFS------MKSFCNEILILS 384 Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723 ++H +L +HG C ++V +YV +G L L + ++ +A Q A A+ Sbjct 385 SINHPNLVKLHGYCSDPRGLLLVHDYVTNGTLADHLHGRGPKMTWRVRLDIALQTALAME 444 Query 724 YLENK---NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV------- 773 YL +VH ++ NI + + IK+ D G+ + E V Sbjct 445 YLHFDIVPPVVHRDITSSNIFVEK-------DMKIKVGDFGLSRLLVFSETTVNSATSSD 497 Query 774 -------ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 +L P+ + L+ D + +G L+E+ +A Q R + Sbjct 498 YVCTGPQGTPGYLDPDY--HRSFRLTEKSDVYSYGVVLMELITGMKAVDQRREKRDMA 553 >sp|Q9LJM4|IKU2_ARATH Receptor-like protein kinase HAIKU2 OS=Arabidopsis thaliana OX=3702 GN=IKU2 PE=1 SV=1 Length=991 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 72/336 (21%), Positives = 128/336 (38%), Gaps = 36/336 (11%) Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK-- 930 + V+ + + +K +G G G V +GE +AVK Sbjct 647 QKKNDWQVSSFRLLNFNEMEIIDEIKSENIIGRGGQGNVYKVSLR-----SGETLAVKHI 701 Query 931 ---------------ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 L + ++ E+ L + H +++K C E S Sbjct 702 WCPESSHESFRSSTAMLSDGNNRSNNGEFEAEVATLSNIKHINVVKL--FCSITCEDSKL 759 Query 976 LVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARN 1028 LV EY+P GSL + L IG A +G+ YLH + IHRD+ + N Sbjct 760 LVYEYMPNGSLWEQLHERRGEQEIGWRVRQALALGAAKGLEYLHHGLDRPVIHRDVKSSN 819 Query 1029 VLLDNDRLVKIGDFGLAKAVP-EGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 +LLD + +I DFGLAK + + + + + APE K SDV+SF Sbjct 820 ILLDEEWRPRIADFGLAKIIQADSVQRDFSAPLVKGTLGYIAPEYAYTTKVNEKSDVYSF 879 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQG---QMTVLRLTELLERGERLPRPDKCPCEV 1144 GV L EL+T ++ + +++ + + +L++ + +V Sbjct 880 GVVLMELVTGKKPLETDFGENNDIVMWVWSVSKETNREMMMKLIDTSIEDEYKEDAL-KV 938 Query 1145 YHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQA 1180 + C + RP ++++ +L+ + Y + Sbjct 939 LTIALLCTDKSPQARPFMKSVVSMLEKIEPSYNKNS 974 Score = 191 bits (485), Expect = 2e-48, Method: Composition-based stats. Identities = 58/364 (16%), Positives = 122/364 (34%), Gaps = 50/364 (14%) Query 542 DDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRT 601 F + N + + + L + + EI + +G+G + Sbjct 625 ALFFLFSYVIFKIRRDKLNKTVQKKNDWQVSSFRLLNFNEMEII-DEIKSENIIGRGGQG 683 Query 602 NVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETAS 660 NVY+ LR + + + +L D ++ F + Sbjct 684 NVYKVSLRSGETLAVKHIWCPESSHESFRSSTA--------MLSDGNNRSNNGEFEAEVA 735 Query 661 LMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMV--VAQQL 718 +S + H ++ + ++V EY+ +G L L RG + W++ +A Sbjct 736 TLSNIKHINVVKLFCSITCEDSKLLVYEYMPNGSLWEQLHERRGEQEIGWRVRQALALGA 795 Query 719 ASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER--- 772 A L YL ++ ++H +V NILL +++D G+ + + Sbjct 796 AKGLEYLHHGLDRPVIHRDVKSSNILLDEEWRP-------RIADFGLAKIIQADSVQRDF 848 Query 773 -----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA----------PLQS 817 + ++APE ++ D + FG L+E+ + + Sbjct 849 SAPLVKGTLGYIAPEYA--YTTKVNEKSDVYSFGVVLMELVTGKKPLETDFGENNDIVMW 906 Query 818 RSPSEKEHFYQRQHRLPEPSCPQ--------LATLTSQCLTYEPTQRPSFRTILRDLTRL 869 KE + +L + S + T+ C P RP ++++ L ++ Sbjct 907 VWSVSKETNREMMMKLIDTSIEDEYKEDALKVLTIALLCTDKSPQARPFMKSVVSMLEKI 966 Query 870 QPHN 873 +P Sbjct 967 EPSY 970 >sp|Q84SN3|CDKF3_ORYSJ Cyclin-dependent kinase F-3 OS=Oryza sativa subsp. japonica OX=39947 GN=CDKF-3 PE=2 SV=1 Length=433 Score = 212 bits (539), Expect = 1e-58, Method: Composition-based stats. Identities = 76/289 (26%), Positives = 116/289 (40%), Gaps = 31/289 (11%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 K IR++G+G G V + N T E+VAVK +K +E+ L+ Sbjct 1 MERYKVIREIGDGTCGNV----FRAYNTETNEIVAVKKMKRKFFQWEECISLREVKALQK 56 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGM 1011 L H +I+K K + E L + E + +L D + + ++ F QI +G+ Sbjct 57 LNHPNIVKLKEVTMENHE--LFFIFENMEC-NLYDVIRERQAAFSEEEIRNFMVQILQGL 113 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 AY+H Y HRDL N+L+ D VKI DFGLA+ V Y D S ++ APE Sbjct 114 AYMHNNGYFHRDLKPENLLVT-DGTVKIADFGLAREVSSSPPY----TDYVSTRWYRAPE 168 Query 1072 CLKEYK-FYYASDVWSFGVTLYELLTHCDSSQ---------------SPPTKFLELIGIA 1115 L + + A D+W+ G L EL T P + G+ Sbjct 169 VLLQSSAYTPAIDMWAVGAILAELFTLSPLFPGGSETDQLYKICAVLGTPDHTVWPEGMN 228 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFEN 1164 + + ++ R P E L++ + RPT E Sbjct 229 LPRSSSFNFFQIPPRNLWELIP-NATLEAIDLIQQLCSWDPRRRPTAEQ 276 Score = 152 bits (385), Expect = 2e-38, Method: Composition-based stats. Identities = 38/258 (15%), Positives = 75/258 (29%), Gaps = 38/258 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + + +G GT NV+ + V +K + Sbjct 1 MERYKVIREIGDGTCGNVFRAY------------------------NTETNEIVAVKKMK 36 Query 646 PSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + +++H ++ + V + E + E +E L +R + Sbjct 37 RKFFQWEECISLREVKALQKLNHPNIVKLKEVTMENHELFFIFENMEC-NLYDVIRERQA 95 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 Q+ L+Y+ N H ++ N+L+ +K++D G+ Sbjct 96 AFSEEEIRNFMVQILQGLAYMHNNGYFHRDLKPENLLVT--------DGTVKIADFGLAR 147 Query 765 GALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 S + V + APE L + + A+D W GA L E+ Sbjct 148 EVSSSPPYTDYVSTRWYRAPEVLLQSSA-YTPAIDMWAVGAILAELFTLSPLFPGGSETD 206 Query 822 EKEHFYQRQHRLPEPSCP 839 + P Sbjct 207 QLYKICAVLGTPDHTVWP 224 >sp|Q6BNF3|STE20_DEBHA Serine/threonine-protein kinase STE20 OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=STE20 PE=3 SV=2 Length=1079 Score = 224 bits (570), Expect = 1e-58, Method: Composition-based stats. Identities = 60/267 (22%), Positives = 119/267 (45%), Gaps = 22/267 (8%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 +G+G G V + +D + + VA+K + + P+ + EI +++ HE+I+ Sbjct 805 MKIGQGASGGVYIA-HDVNHRS--QTVAIKQMNLEQQPK-KELIINEILVMKGSKHENIV 860 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + +G+ L +VMEY+ GSL + + + Q+ ++ +G+ +LH++ I Sbjct 861 NFIDSYLLRGD--LWVVMEYMEGGSLTEIVTHSVMTEGQIGAVCRETLKGLRFLHSKGVI 918 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ + N+LL+ D +K+ DFG + +E R +W APE + ++ Sbjct 919 HRDIKSDNILLNIDGNIKMTDFGFCAQI---NEINLKRTTMVGTPYWMAPEVVSRKEYGP 975 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 DVWS G+ + E++ + T L IA +L P+ Sbjct 976 KVDVWSLGIMIIEMI-EGEPPYLNETPLRALYLIATNGTP------------KLKEPEAL 1022 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIP 1167 ++ + C + + + R + L+ Sbjct 1023 SYDIRKFLSWCLQVDFNKRGNADQLLN 1049 Score = 179 bits (455), Expect = 2e-44, Method: Composition-based stats. Identities = 56/303 (18%), Positives = 99/303 (33%), Gaps = 43/303 (14%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L Q+ + L +GQG VY + + Sbjct 788 LQQICSEGDPNELYKDLMKIGQGASGGVY-----------------------IAHDVNHR 824 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 V +K ++ +M H ++ + + +V EY+E G L Sbjct 825 SQTVAIKQMNLEQQPKKELIINEILVMKGSKHENIVNFIDSYLLRGDLWVVMEYMEGGSL 884 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 + + V ++ L +L +K ++H ++ NILL G I Sbjct 885 TEIVTHS--VMTEGQIGAVCRETLKGLRFLHSKGVIHRDIKSDNILLNIDG-------NI 935 Query 756 KLSDPGVGLGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDG 811 K++D G L R V W+APE + +D W G ++E+ +G Sbjct 936 KMTDFGFCAQINEINLKRTTMVGTPYWMAPEVVS--RKEYGPKVDVWSLGIMIIEMI-EG 992 Query 812 EAPLQSRSPSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 E P + +P + PE + S CL + +R + +L D Sbjct 993 EPPYLNETPLRALYLIATNGTPKLKEPEALSYDIRKFLSWCLQVDFNKRGNADQLLNDKF 1052 Query 868 RLQ 870 L+ Sbjct 1053 ILE 1055 >sp|O74456|PEF1_SCHPO Serine/threonine-protein kinase pef1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=pef1 PE=3 SV=2 Length=288 Score = 207 bits (526), Expect = 1e-58, Method: Composition-based stats. Identities = 56/212 (26%), Positives = 105/212 (50%), Gaps = 15/212 (7%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 +++ LGEG + V Y N TGE+VA+K ++ D S +EI +++ L Sbjct 1 MNYQRLEKLGEGTYAHV----YKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKEL 56 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP----RHSIGLAQLLLFAQQICEG 1010 H +I+ Q E L LV EY+ L+ Y+ + ++ +Q+ F QQ+ +G Sbjct 57 RHPNIMSLSDVL--QTENKLMLVFEYMEK-DLKKYMDTYGNQGALPPSQVKNFTQQLLKG 113 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 +++ H +HRDL +N+L+++ +K+ DFGLA+++ + +++ AP Sbjct 114 ISFCHENRVLHRDLKPQNLLINSRGELKLADFGLARSIGIP---VNTFSNEVVTLWYRAP 170 Query 1071 ECLKEYK-FYYASDVWSFGVTLYELLTHCDSS 1101 + L + + + D+WS G + E+ T Sbjct 171 DVLLGSRVYSTSIDIWSVGCIMAEMATGRPLF 202 Score = 167 bits (422), Expect = 1e-44, Method: Composition-based stats. Identities = 55/264 (21%), Positives = 103/264 (39%), Gaps = 40/264 (15%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 +L LG+GT +VY+G+ RV G V LKV+ Sbjct 2 NYQRLEKLGEGTYAHVYKGQNRVTGE------------------------IVALKVIRID 37 Query 648 HHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL--RRERG 704 + SLM ++ H ++ + V + ++V EY+E L ++ +G Sbjct 38 ADEGTPSTAIREISLMKELRHPNIMSLSDVLQTENKLMLVFEYMEK-DLKKYMDTYGNQG 96 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 +P + QQL +S+ ++H ++ +N+L+ G +KL+D G+ Sbjct 97 ALPPSQVKNFTQQLLKGISFCHENRVLHRDLKPQNLLINSRGE-------LKLADFGLAR 149 Query 765 GA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 + V + + AP+ L G+ ST++D W G + E+ S + Sbjct 150 SIGIPVNTFSNEVVTLWYRAPDVLL-GSRVYSTSIDIWSVGCIMAEMATGRPLFAGSNNE 208 Query 821 SEKEHFYQRQHRLPEPSCPQLATL 844 + ++ E S P ++ L Sbjct 209 DQLLKIFRLLGTPTEQSWPGISLL 232 >sp|Q7ZX15|AKT2A_XENLA RAC-beta serine/threonine-protein kinase A OS=Xenopus laevis OX=8355 GN=akt2-a PE=2 SV=1 Length=486 Score = 213 bits (543), Expect = 1e-58, Method: Composition-based stats. Identities = 68/309 (22%), Positives = 106/309 (34%), Gaps = 28/309 (9%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 Q P + + + + ++ LG+G FGKV L Sbjct 114 NQVPEDEEEEAMEVKYGSPSDVSSAEQMDVAMSKGHPKVTMNDFDYLKLLGKGTFGKVIL 173 Query 914 YCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE 971 TG A+K L+ + + E +L+ H + K Q Sbjct 174 V----REKATGRYYAMKILRKEVIIAKDEVAHTLTESRVLQNTKHPFLTALKYAF--QTS 227 Query 972 KSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030 L VMEY G L +L R + + +I + YLH+++ ++RD+ N++ Sbjct 228 DRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRNVVYRDIKLENLM 287 Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 LD D VKI DFGL K EG + APE L++ + A D W GV Sbjct 288 LDKDGHVKITDFGLCK---EGITDGATMRTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVV 344 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 +YE++ Q +L R PR E L+ Sbjct 345 MYEMMCGRLPF--------------YNQDHERLFELILMEEIRFPR--TLSPEAKSLLAG 388 Query 1151 CWETEASFR 1159 + + R Sbjct 389 LLKKDPKQR 397 Score = 167 bits (423), Expect = 8e-43, Method: Composition-based stats. Identities = 56/283 (20%), Positives = 96/283 (34%), Gaps = 43/283 (15%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +V + L LG+GT V + R++ + Sbjct 150 PKVTMNDFDYLKLLGKGTFGKV------------------------ILVREKATGRYYAM 185 Query 642 KVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 K+L + ++ H L + V EY G L Sbjct 186 KILRKEVIIAKDEVAHTLTESRVLQNTKHPFLTALKYAFQTSDRLCFVMEYANGGELFFH 245 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 L RER ++ SAL YL ++N+V+ ++ N++L + G +K++ Sbjct 246 LSRER-VFTEDRARFYGAEIVSALEYLHSRNVVYRDIKLENLMLDKDG-------HVKIT 297 Query 759 DPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 D G+ ++ +LAPE L N A+D WG G + E+ G P Sbjct 298 DFGLCKEGITDGATMRTFCGTPEYLAPEVLED--NDYGRAVDWWGLGVVMYEMMC-GRLP 354 Query 815 LQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 ++ + R P P+ +L + L +P QR Sbjct 355 FYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQR 397 >sp|Q86SG6|NEK8_HUMAN Serine/threonine-protein kinase Nek8 OS=Homo sapiens OX=9606 GN=NEK8 PE=1 SV=1 Length=692 Score = 218 bits (556), Expect = 1e-58, Method: Composition-based stats. Identities = 66/269 (25%), Positives = 120/269 (45%), Gaps = 30/269 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V L ++V +K + + + R + E +L+ L H ++I+ Sbjct 10 VGRGAFGIVHLCLRKA----DQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIE 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018 Y + +K+L + MEY P G+L +++ + + +L F QI + ++H Sbjct 66 YYENFLE--DKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHL 123 Query 1019 YIHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL +N+LLD +VKIGDFG++K + + Y V + +PE + Sbjct 124 ILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTV----VGTPCYISPELCEGKP 179 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + SD+W+ G LYEL + + ++ L L + G P Sbjct 180 YNQKSDIWALGCVLYELASLKRAFEAANLPALVL---------------KIMSGTFAPIS 224 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 D+ E+ L+ + E + RP +++ Sbjct 225 DRYSPELRQLVLSLLSLEPAQRPPLSHIM 253 Score = 166 bits (419), Expect = 5e-41, Method: Composition-based stats. Identities = 44/292 (15%), Positives = 101/292 (35%), Gaps = 39/292 (13%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ ++ +G+G V+ + + + V++K + Sbjct 1 MEKYERIRVVGRGAFGIVHLCLRKAD------------------------QKLVIIKQIP 36 Query 646 PSHH--DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + A ++ ++H ++ + + ++ EY G L ++++ Sbjct 37 VEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRC 96 Query 704 GH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + + Q+ AL ++ ++H ++ +NILL + +K+ D G+ Sbjct 97 NSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKH------RMVVKIGDFGI 150 Query 763 GLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 S+ V +++PE G + D W G L E+ A + Sbjct 151 SKILSSKSKAYTVVGTPCYISPELCEG--KPYNQKSDIWALGCVLYELASLKRAFEAANL 208 Query 820 PSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P+ + + P+L L L+ EP QRP I+ ++ Sbjct 209 PALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIR 260 >sp|Q19469|SAD1_CAEEL Serine/threonine kinase SAD-1 OS=Caenorhabditis elegans OX=6239 GN=sad-1 PE=1 SV=2 Length=914 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 76/310 (25%), Positives = 128/310 (41%), Gaps = 29/310 (9%) Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920 I L + + +++ N S + K + LG+G G V T+ Sbjct 11 EINSKLAAVNNELSSKIMSENIVSTRPVAQAQYCGPYKLEKTLGKGQTGLVKTG----TH 66 Query 921 DGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979 TG VA+K + + + ++EI I++ + H H++ E++ K L L++E Sbjct 67 CITGRKVAIKIVNKEKLSESVLQKVEREIAIMKLIEHPHVLHLYDVYENK--KYLYLLLE 124 Query 980 YVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 +V G L DYL + + + F +QI + + HA + HRDL N+LLD +K Sbjct 125 HVSGGELFDYLVRKGRLMSKEARKFFRQIISALDFCHAHNICHRDLKPENLLLDERNNIK 184 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTH 1097 + DFG+A EG + E + PE ++ K+ +DVWS GV LY LL Sbjct 185 VADFGMASLQVEG----SMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVG 240 Query 1098 CDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEAS 1157 + L E ++RG P P +V L++ E + Sbjct 241 ALPFDDD---------------NLRNLLEKVKRGV-FHIPHFVPADVQSLLRAMIEVDPG 284 Query 1158 FRPTFENLIP 1167 R + ++ Sbjct 285 KRYSLADVFK 294 Score = 165 bits (418), Expect = 2e-40, Method: Composition-based stats. Identities = 53/322 (16%), Positives = 106/322 (33%), Gaps = 44/322 (14%) Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEI----TQLSHLGQGTRTNVYEGRLRVE 611 GE ++ + S + ++ + +S V Q + LG+G V G + Sbjct 10 GEINSKLAAVNNELSSKIMSENIVSTRPVAQAQYCGPYKLEKTLGKGQTGLVKTGTHCIT 69 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--HHDIALAFYETASLMSQVSHTH 669 G +V +K+++ + ++M + H H Sbjct 70 GR------------------------KVAIKIVNKEKLSESVLQKVEREIAIMKLIEHPH 105 Query 670 LAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN 729 + ++ V ++ E+V G L +L +G + +Q+ SAL + N Sbjct 106 VLHLYDVYENKKYLYLLLEHVSGGELFDYL-VRKGRLMSKEARKFFRQIISALDFCHAHN 164 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR---EERVERIPWLAPECLPG 786 + H ++ N+LL IK++D G+ + E + PE + G Sbjct 165 ICHRDLKPENLLLDERN-------NIKVADFGMASLQVEGSMLETSCGSPHYACPEVIRG 217 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-HRLPEPSCPQLATLT 845 D W G L + G P + +R +P + +L Sbjct 218 EKYD-GRKADVWSCGVILYALLV-GALPFDDDNLRNLLEKVKRGVFHIPHFVPADVQSLL 275 Query 846 SQCLTYEPTQRPSFRTILRDLT 867 + +P +R S + + Sbjct 276 RAMIEVDPGKRYSLADVFKHPW 297 >sp|Q02723|RKIN1_SECCE Carbon catabolite-derepressing protein kinase OS=Secale cereale OX=4550 GN=RKIN1 PE=2 SV=1 Length=502 Score = 214 bits (544), Expect = 2e-58, Method: Composition-based stats. Identities = 74/283 (26%), Positives = 108/283 (38%), Gaps = 33/283 (12%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQE 947 + + LG G F KV + + T VA+K L P+ K+E Sbjct 7 HSEALKNYYLGKILGVGTFAKVII----AEHKHTRHKVAIKVLNRRQMRAPEMEEKAKRE 62 Query 948 IDILRT---LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY-LPRHSIGLAQLLLF 1003 I ILR L H HII+ K + +VMEY G L DY L + + + Sbjct 63 IKILRLFIDLIHPHIIRVYEVIV--TPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRT 120 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 QQI + Y H +HRDL N+LLD+ VK+ DFGL+ + +GH + Sbjct 121 FQQIISAVEYCHRNKVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGH----FLKTSCG 176 Query 1064 PVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVL 1122 + + APE + + DVWS GV LY LL + Sbjct 177 SLNYAAPEVISGKLYAGPEIDVWSCGVILYALLCGAVPFDDD---------------NIP 221 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L + ++ G + P V L+ + R T + Sbjct 222 NLFKKIKGGTYI-LPIYLSDLVRDLISRMLIVDPMKRITIGEI 263 Score = 175 bits (444), Expect = 2e-45, Method: Composition-based stats. Identities = 54/335 (16%), Positives = 102/335 (30%), Gaps = 42/335 (13%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 H K LG GT V + + +V + Sbjct 7 HSEALKNYYLGKILGVGTFAKV------------------------IIAEHKHTRHKVAI 42 Query 642 KVLDPSHH---DIALAFYETASLMS---QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 KVL+ ++ ++ + H H+ V+ V V + +V EY ++G L Sbjct 43 KVLNRRQMRAPEMEEKAKREIKILRLFIDLIHPHIIRVYEVIVTPKDIFVVMEYCQNGDL 102 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 ++ +R + QQ+ SA+ Y +VH ++ N+LL + Sbjct 103 LDYILEKR-RLQEDEARRTFQQIISAVEYCHRNKVVHRDLKPENLLLDSK-------YNV 154 Query 756 KLSDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 KL+D G+ + + + APE + G + +D W G L + Sbjct 155 KLADFGLSNVMHDGHFLKTSCGSLNYAAPEVISGKLYA-GPEIDVWSCGVILYALLCGAV 213 Query 813 APLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 P+ + + LP + L S+ L +P +R + I + Sbjct 214 PFDDDNIPNLFKKIKGGTYILPIYLSDLVRDLISRMLIVDPMKRITIGEIRKHSWFQNRL 273 Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGH 907 + + + H Sbjct 274 PRYLAVPPPDMMQQAKMIDEDTLRDVVKLGYDKDH 308 >sp|P06493|CDK1_HUMAN Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3 Length=297 Score = 207 bits (526), Expect = 2e-58, Method: Composition-based stats. Identities = 62/287 (22%), Positives = 117/287 (41%), Gaps = 29/287 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ Sbjct 1 MEDYTKIEKIGEGTYGVV----YKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQIC 1008 L H +I+ + + L L+ E++ + L+ YL P + + + + QI Sbjct 57 ELRHPNIVSLQDVLMQ--DSRLYLIFEFLSM-DLKKYLDSIPPGQYMDSSLVKSYLYQIL 113 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +G+ + H++ +HRDL +N+L+D+ +K+ DFGLA+A RV +++ Sbjct 114 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP---IRVYTHEVVTLWYR 170 Query 1069 APECLKEY-KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 +PE L ++ D+WS G EL T + Sbjct 171 SPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPE 230 Query 1128 LE--RGERLPRPDKCPCEVY-----------HLMKNCWETEASFRPT 1161 +E + + P P + L+ + + R + Sbjct 231 VESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRIS 277 Score = 165 bits (417), Expect = 5e-44, Method: Composition-based stats. Identities = 41/267 (15%), Positives = 95/267 (36%), Gaps = 41/267 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ T++ +G+GT VY+GR + G V +K + Sbjct 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQ------------------------VVAMKKIR 36 Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-- 701 + + SL+ ++ H ++ + V ++ ++ E++ L +L Sbjct 37 LESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 ++ + Q+ + + ++ ++H ++ +N+L+ G IKL+D G Sbjct 96 PGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKG-------TIKLADFG 148 Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + V + + +PE L G+ ST +D W G E+ Sbjct 149 LARAFGIPIRVYTHEVVTLWYRSPEVLL-GSARYSTPVDIWSIGTIFAELATKKPLFHGD 207 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ P++ +L Sbjct 208 SEIDQLFRIFRALGTPNNEVWPEVESL 234 >sp|D3ZGQ5|NEK8_RAT Serine/threonine-protein kinase Nek8 OS=Rattus norvegicus OX=10116 GN=Nek8 PE=1 SV=1 Length=698 Score = 218 bits (556), Expect = 2e-58, Method: Composition-based stats. Identities = 66/269 (25%), Positives = 120/269 (45%), Gaps = 30/269 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V L ++V +K + + + R + E +L+ L H ++I+ Sbjct 10 VGRGAFGIVHLCLRKA----DQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIE 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018 Y + +K+L + MEY P G+L +++ + + +L F QI + ++H Sbjct 66 YYENFLE--DKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHL 123 Query 1019 YIHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL +N+LLD +VKIGDFG++K + + Y V + +PE + Sbjct 124 ILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTV----VGTPCYISPELCEGKP 179 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + SD+W+ G LYEL + + ++ L L + G P Sbjct 180 YNQKSDIWALGCVLYELASLKRAFEAANLPALVL---------------KIMSGTFAPIS 224 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 D+ E+ L+ + E + RP +++ Sbjct 225 DRYSPELRQLVLSLLSLEPAQRPPLSHIM 253 Score = 166 bits (419), Expect = 5e-41, Method: Composition-based stats. Identities = 44/292 (15%), Positives = 101/292 (35%), Gaps = 39/292 (13%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ ++ +G+G V+ + + + V++K + Sbjct 1 MEKYERIRVVGRGAFGIVHLCLRKAD------------------------QKLVIIKQIP 36 Query 646 PSHH--DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + A ++ ++H ++ + + ++ EY G L ++++ Sbjct 37 VEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRC 96 Query 704 GH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + + Q+ AL ++ ++H ++ +NILL + +K+ D G+ Sbjct 97 NSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKH------RMVVKIGDFGI 150 Query 763 GLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 S+ V +++PE G + D W G L E+ A + Sbjct 151 SKILSSKSKAYTVVGTPCYISPELCEG--KPYNQKSDIWALGCVLYELASLKRAFEAANL 208 Query 820 PSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P+ + + P+L L L+ EP QRP I+ ++ Sbjct 209 PALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIR 260 >sp|P35567|CDK1A_XENLA Cyclin-dependent kinase 1-A OS=Xenopus laevis OX=8355 GN=cdk1-a PE=1 SV=1 Length=302 Score = 207 bits (526), Expect = 2e-58, Method: Composition-based stats. Identities = 68/303 (22%), Positives = 125/303 (41%), Gaps = 33/303 (11%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ Sbjct 1 MDEYTKIEKIGEGTYGVV----YKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQIC 1008 L H +I+ + L L+ E++ + L+ YL I + + QI Sbjct 57 ELQHPNIVCLLDVLMQ--DSRLYLIFEFLSM-DLKKYLDSIPSGQYIDTMLVKSYLYQIL 113 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +G+ + H++ +HRDL +N+L+D+ ++K+ DFGLA+A RV +++ Sbjct 114 QGIVFCHSRRVLHRDLKPQNLLIDSKGVIKLADFGLARAFGIP---VRVYTHEVVTLWYR 170 Query 1069 APECLKEY-KFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQMTVL 1122 APE L ++ DVWS G E+ T H DS + +G ++ Sbjct 171 APEVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEV-WP 229 Query 1123 RLTELLERGERLPR---------PDKCPCEVYHLMKNCWETEASFRPTFEN--LIPILKT 1171 + L + P+ + L+ + + R + L P Sbjct 230 EVESLQDYKNSFPKWKGGSLSANVKNIDKDGLDLLAKMLIYDPAKRISARKALLHPYFDD 289 Query 1172 VHE 1174 + + Sbjct 290 LDK 292 Score = 169 bits (427), Expect = 3e-45, Method: Composition-based stats. Identities = 45/267 (17%), Positives = 94/267 (35%), Gaps = 41/267 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 E T++ +G+GT VY+GR + G V +K Sbjct 1 MDEYTKIEKIGEGTYGVVYKGRHKATGQ------------------------VVAMKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-- 701 L+ + SL+ ++ H ++ + V ++ ++ E++ L +L Sbjct 37 LENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 ++ Q+ + + ++ ++H ++ +N+L+ G+ IKL+D G Sbjct 96 SGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDSKGV-------IKLADFG 148 Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + V + + APE L G+ ST +D W G EI Sbjct 149 LARAFGIPVRVYTHEVVTLWYRAPEVLL-GSVRYSTPVDVWSIGTIFAEIATKKPLFHGD 207 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ P++ +L Sbjct 208 SEIDQLFRIFRALGTPNNEVWPEVESL 234 >sp|Q61083|M3K2_MOUSE Mitogen-activated protein kinase kinase kinase 2 OS=Mus musculus OX=10090 GN=Map3k2 PE=1 SV=2 Length=619 Score = 217 bits (552), Expect = 2e-58, Method: Composition-based stats. Identities = 73/281 (26%), Positives = 126/281 (45%), Gaps = 24/281 (9%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL----KADCGPQHRSGWKQ 946 + + LG+G FG+V L + TG +AVK + ++ + + + Sbjct 350 PRAPTNWRLGKLLGQGAFGRVYLCY----DVDTGRELAVKQVQFNPESPETSKEVNALEC 405 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQ 1005 EI +L+ L HE I++Y GC D EK+L + ME P GS++D L + + + + Sbjct 406 EIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKAYGALTENVTRKYTR 465 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 QI EG+ YLH+ +HRD+ N+L D+ +K+GDFG +K + + Sbjct 466 QILEGVHYLHSNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTP 525 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 +W +PE + + +D+WS T+ E+LT + PP E + + Sbjct 526 YWMSPEVISGEGYGRKADIWSVACTVVEMLT-----EKPPWAEFEAMA---------AIF 571 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 ++ + P +K + EA RP+ E L+ Sbjct 572 KIATQPTNPKLPPHVSDYTRDFLKRIF-VEAKLRPSAEELL 611 Score = 158 bits (400), Expect = 5e-39, Method: Composition-based stats. Identities = 63/335 (19%), Positives = 104/335 (31%), Gaps = 52/335 (16%) Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQK---EITQLSHLGQGTRTNVYEGRLRVE 611 P + I RG+ TL ++ +S + LGQG VY Sbjct 319 PEYDDSRIRRRGSDIDNPTLTVTDISPPSRSPRAPTNWRLGKLLGQGAFGRVY------- 371 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE---TASLMSQVSHT 668 L D G+EL V +P + + L+ + H Sbjct 372 ---------------LCYDVDTGRELAVKQVQFNPESPETSKEVNALECEIQLLKNLLHE 416 Query 669 HLAFVHGVCVRGPE--NIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLE 726 + +G E + E G + L+ G + +Q+ + YL Sbjct 417 RIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKA-YGALTENVTRKYTRQILEGVHYLH 475 Query 727 NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG-------VGLGALSREERVERIPWL 779 + +VH ++ G NIL ++ IKL D G + L + W+ Sbjct 476 SNMIVHRDIKGANIL-------RDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTPYWM 528 Query 780 APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCP 839 +PE + G D W T++E+ E P + + F P Sbjct 529 SPEVISG--EGYGRKADIWSVACTVVEMLT--EKPPWAEFEAMAAIFKIATQPTNPKLPP 584 Query 840 QLATLTSQCLTY---EPTQRPSFRTILRDLTRLQP 871 ++ T L E RPS +LR + Sbjct 585 HVSDYTRDFLKRIFVEAKLRPSAEELLRHMFVHYH 619 >sp|O64477|Y2913_ARATH G-type lectin S-receptor-like serine/threonine-protein kinase At2g19130 OS=Arabidopsis thaliana OX=3702 GN=At2g19130 PE=2 SV=1 Length=828 Score = 221 bits (562), Expect = 2e-58, Method: Composition-based stats. Identities = 77/300 (26%), Positives = 127/300 (42%), Gaps = 23/300 (8%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQ 946 LG G FG V ++D +AVK L + Q ++ Sbjct 483 FSYRELQNATKNFSDKLGGGGFGSVFKGALPDSSD-----IAVKRL--EGISQGEKQFRT 535 Query 947 EIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL------PRHSIGLAQL 1000 E+ + T+ H ++++ +G C + +K LV +Y+P GSL +L + +G Sbjct 536 EVVTIGTIQHVNLVRLRGFCSEGSKK--LLVYDYMPNGSLDSHLFLNQVEEKIVLGWKLR 593 Query 1001 LLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 A G+AYLH + IH D+ N+LLD+ K+ DFGLAK V G ++ RV Sbjct 594 FQIALGTARGLAYLHDECRDCIIHCDIKPENILLDSQFCPKVADFGLAKLV--GRDFSRV 651 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS-QSPPTKFLELIGIAQ 1116 + APE + +DV+S+G+ L+EL++ ++ QS K A Sbjct 652 LTTMRGTRGYLAPEWISGVAITAKADVYSYGMMLFELVSGRRNTEQSENEKVRFFPSWAA 711 Query 1117 GQMTVL-RLTELLERGERLPRPD-KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 +T + L++ D + + C + E S RP ++ IL+ V E Sbjct 712 TILTKDGDIRSLVDPRLEGDAVDIEEVTRACKVACWCIQDEESHRPAMSQVVQILEGVLE 771 Score = 196 bits (499), Expect = 2e-50, Method: Composition-based stats. Identities = 51/271 (19%), Positives = 91/271 (34%), Gaps = 48/271 (18%) Query 575 NLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRG 634 LS S+ + LG G +V++G L Sbjct 479 TLSAFSYRELQNATKNFSDKLGGGGFGSVFKGALPDSSD--------------------- 517 Query 635 QELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 + +K L F + + H +L + G C G + ++V +Y+ +G Sbjct 518 ----IAVKRL-EGISQGEKQFRTEVVTIGTIQHVNLVRLRGFCSEGSKKLLVYDYMPNGS 572 Query 695 LDVWLR----RERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGL 747 LD L E+ + + +A A L+YL + ++H ++ NILL Sbjct 573 LDSHLFLNQVEEKIVLGWKLRFQIALGTARGLAYLHDECRDCIIHCDIKPENILLDSQFC 632 Query 748 AEGTSPFIKLSDPGVGLGALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGA 802 K++D G+ RV +LAPE + G A ++ D + +G Sbjct 633 P-------KVADFGLAKLVGRDFSRVLTTMRGTRGYLAPEWISGVA--ITAKADVYSYGM 683 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL 833 L E+ G + + F + Sbjct 684 MLFELVS-GRRNTEQSENEKVRFFPSWAATI 713 >sp|Q6BRY2|PHO85_DEBHA Negative regulator of the PHO system OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=PHO85 PE=3 SV=2 Length=330 Score = 208 bits (529), Expect = 2e-58, Method: Composition-based stats. Identities = 69/297 (23%), Positives = 122/297 (41%), Gaps = 30/297 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 +++ LGEG + V Y N G++VA+K + D S +EI Sbjct 1 MTGSSSQFQQLEKLGEGTYATV----YKGRNRTNGQLVALKEINLDSEEGTPSTAIREIS 56 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQ 1005 +++ L HE+I+ E L LV E++ L+ Y+ H + L + F Sbjct 57 LMKELDHENIVTLYDVI--HTENKLTLVFEFMDK-DLKKYMEAHGNQGALDLKIVKSFIF 113 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 Q+ +G+ + H +HRDL +N+L++N +K+GDFGLA+A + + + Sbjct 114 QLLKGIMFCHDNRVLHRDLKPQNLLINNKGELKLGDFGLARAFGIP---FNTFSNEVVTL 170 Query 1066 FWYAPECLKEYKFYYAS-DVWSFGVTLYELLTHCD-----SSQSPPTKFLELIGIAQGQ- 1118 ++ AP+ L + Y AS D+WS G E+ T S+ K L+G + Sbjct 171 WYRAPDVLLGSRAYTASIDIWSAGCIFAEMCTGKPLFPGTSNDDQLIKIFRLMGTPNERT 230 Query 1119 --------MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + RL P+ + +L+ + + R T + Sbjct 231 WPGVSSYANFKNNWQIFVPQDLRLLIPNLDSMGL-NLLSSLLQMRPDARITARQALQ 286 Score = 168 bits (425), Expect = 1e-44, Method: Composition-based stats. Identities = 46/264 (17%), Positives = 99/264 (38%), Gaps = 40/264 (15%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + QL LG+GT VY+GR R G V LK ++ Sbjct 6 SQFQQLEKLGEGTYATVYKGRNRTNGQ------------------------LVALKEINL 41 Query 647 SHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL--RRER 703 + SLM ++ H ++ ++ V + +V E+++ L ++ + Sbjct 42 DSEEGTPSTAIREISLMKELDHENIVTLYDVIHTENKLTLVFEFMDK-DLKKYMEAHGNQ 100 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 G + + QL + + + ++H ++ +N+L+ G +KL D G+ Sbjct 101 GALDLKIVKSFIFQLLKGIMFCHDNRVLHRDLKPQNLLINNKGE-------LKLGDFGLA 153 Query 764 LG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + V + + AP+ L G+ + + ++D W G E+C + + Sbjct 154 RAFGIPFNTFSNEVVTLWYRAPDVLL-GSRAYTASIDIWSAGCIFAEMCTGKPLFPGTSN 212 Query 820 PSEKEHFYQRQHRLPEPSCPQLAT 843 + ++ E + P +++ Sbjct 213 DDQLIKIFRLMGTPNERTWPGVSS 236 >sp|P97377|CDK2_MOUSE Cyclin-dependent kinase 2 OS=Mus musculus OX=10090 GN=Cdk2 PE=1 SV=2 Length=346 Score = 208 bits (530), Expect = 2e-58, Method: Composition-based stats. Identities = 61/206 (30%), Positives = 102/206 (50%), Gaps = 15/206 (7%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y N TGE+VA+K ++ D + S +EI +L+ Sbjct 1 MENFQKVEKIGEGTYGVV----YKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH---SIGLAQLLLFAQQICE 1009 L H +I+K E L LV E++ L+ ++ I L + + Q+ + Sbjct 57 ELNHPNIVKLLDVI--HTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQ 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 G+A+ H+ +HRDL +N+L++ + +K+ DFGLA+A R +++ A Sbjct 114 GLAFCHSHRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVP---VRTYTHEVVTLWYRA 170 Query 1070 PECLKEYKFY-YASDVWSFGVTLYEL 1094 PE L K+Y A D+WS G E+ Sbjct 171 PEILLGCKYYSTAVDIWSLGCIFAEM 196 Score = 166 bits (420), Expect = 8e-44, Method: Composition-based stats. Identities = 45/229 (20%), Positives = 87/229 (38%), Gaps = 40/229 (17%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 + ++ +G+GT VY+ + ++ G V LK Sbjct 1 MENFQKVEKIGEGTYGVVYKAKNKLTGE------------------------VVALKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 LD + SL+ +++H ++ + V + +V E++ H L ++ Sbjct 37 LDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFL-HQDLKKFMDASA 95 Query 704 -GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 +P+ QL L++ + ++H ++ +N+L+ G IKL+D G+ Sbjct 96 LTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAEG-------SIKLADFGL 148 Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 + V + + APE L G STA+D W G E+ Sbjct 149 ARAFGVPVRTYTHEVVTLWYRAPEILLGCKY-YSTAVDIWSLGCIFAEM 196 >sp|P22517|KCC2_YEAST Calcium/calmodulin-dependent protein kinase II OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CMK2 PE=1 SV=2 Length=447 Score = 212 bits (539), Expect = 2e-58, Method: Composition-based stats. Identities = 67/316 (21%), Positives = 106/316 (34%), Gaps = 26/316 (8%) Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918 D+ + N V + ++ R LG G FG V Sbjct 9 NSEFHVDVQDPERLNGHPVAKFINKLSGQPESYVNRTNYIFGRTLGAGSFGVVR----QA 64 Query 919 TNDGTGEMVAVKALKADCGPQ---HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQ 975 T E VA+K L +E+ IL+ L H +I+ +K E + + Sbjct 65 RKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDK--FY 122 Query 976 LVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL--- 1031 +V + G L D L R + QI + Y+H+++ +HRDL NVL Sbjct 123 IVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDK 182 Query 1032 DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTL 1091 + + I DFG+AK + + + + APE L + D+WS GV Sbjct 183 SENSPLVIADFGIAKQLKGEEDLIYK---AAGSLGYVAPEVLTQDGHGKPCDIWSIGVIT 239 Query 1092 YELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNC 1151 Y LL + + A +P D +V + Sbjct 240 YTLLCGYSPFIAESVEGFMEECTASRYPVTF----------HMPYWDNISIDVKRFILKA 289 Query 1152 WETEASFRPTFENLIP 1167 + RPT L+ Sbjct 290 LRLNPADRPTATELLD 305 Score = 159 bits (403), Expect = 2e-40, Method: Composition-based stats. Identities = 49/299 (16%), Positives = 93/299 (31%), Gaps = 47/299 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V++ LG G+ V R V +K+ Sbjct 42 VNRTNYIFGRTLGAGSFGVV------------------------RQARKLSTNEDVAIKI 77 Query 644 LDPSHHDIA----LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 L YE S++ ++SH ++ + +VT+ G L + Sbjct 78 LLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRI 137 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 RG + + Q+ A+ Y+ +KN+VH ++ N+L + + + + ++D Sbjct 138 L-SRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVL----YVDKSENSPLVIAD 192 Query 760 PGVGLGALSREE----RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ E+ + ++APE L + D W G + G +P Sbjct 193 FGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQ--DGHGKPCDIWSIGVITYTLLC-GYSPF 249 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQ-------LATLTSQCLTYEPTQRPSFRTILRDLT 867 + S P + + L P RP+ +L D Sbjct 250 IAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPW 308 >sp|W0LYS5|CAMKI_MACNP Calcium/calmodulin-dependent protein kinase type 1 OS=Macrobrachium nipponense OX=159736 GN=CaMKI PE=2 SV=1 Length=345 Score = 208 bits (530), Expect = 2e-58, Method: Composition-based stats. Identities = 64/270 (24%), Positives = 103/270 (38%), Gaps = 30/270 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G F +V L + +VA+K + + EI +LR L H +I++ Sbjct 37 LGTGAFSQVRLAEVK---EDPSRVVAIKIIDKKALKGKEDSLENEIRVLRRLQHPNIVQL 93 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYIH 1021 ED+ + + L++E V G L D + + S +Q+ E + Y+H Q +H Sbjct 94 METYEDR--EHVYLIIELVTGGELFDRIVEKGSYTEKDASDLIRQVLEAVDYMHDQGVVH 151 Query 1022 RDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 RDL N+L D D + I DFGL+K G + + APE L + + Sbjct 152 RDLKPENLLYYSPDEDSKIMISDFGLSKMEDSG-----IMATACGTPGYVAPEVLAQKPY 206 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP- 1137 A DVWS GV Y LL + ++L+ P Sbjct 207 GKAVDVWSIGVIAYILLCGYPPF--------------YDENDANLFAQILKGEFEFDSPY 252 Query 1138 -DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 D+ ++ + R T + + Sbjct 253 WDEISESAKDFIRQLMCVDVEKRYTCKQAL 282 Score = 152 bits (385), Expect = 4e-39, Method: Composition-based stats. Identities = 38/237 (16%), Positives = 76/237 (32%), Gaps = 34/237 (14%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + + LG G + V ++ + S V +K++D Sbjct 28 EDKYILKDLLGTGAFSQVRLAEVKEDPS-----------------------RVVAIKIID 64 Query 646 PSHHDIALA-FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 ++ ++ H ++ + ++ E V G L + E+G Sbjct 65 KKALKGKEDSLENEIRVLRRLQHPNIVQLMETYEDREHVYLIIELVTGGELFDRI-VEKG 123 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + +Q+ A+ Y+ ++ +VH ++ N+L + I +SD G+ Sbjct 124 SYTEKDASDLIRQVLEAVDYMHDQGVVHRDLKPENLL----YYSPDEDSKIMISDFGLSK 179 Query 765 GALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 S ++APE L A+D W G I G P + Sbjct 180 MEDSGIMATACGTPGYVAPEVLAQ--KPYGKAVDVWSIGVIAY-ILLCGYPPFYDEN 233 >sp|G5EEN4|GCK3_CAEEL Germinal center kinase 3 OS=Caenorhabditis elegans OX=6239 GN=gck-3 PE=1 SV=1 Length=596 Score = 216 bits (550), Expect = 2e-58, Method: Composition-based stats. Identities = 66/300 (22%), Positives = 111/300 (37%), Gaps = 28/300 (9%) Query 885 PASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW 944 +D K +G G V P N E VA+K + + Sbjct 96 NPADRWPTEPSAYKLDESIGVGATATVFTAYCLPRN----EKVAIKCINLEKCQTSVDEL 151 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---------- 994 EI + H +++ Y Q E L +VM + GS+ D L R Sbjct 152 SHEIQAMSQCNHPNVVSYYTSFIAQEE--LWVVMRLLNCGSMLDILKRKVKAIGKEQAQF 209 Query 995 --IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 + + +++ +G+ Y H IHRD+ A N+LL +D ++I DFG++ + Sbjct 210 GVLDEVSIATVLREVLKGLEYFHLNGQIHRDIKAGNILLADDGTIQIADFGVSGWLASSG 269 Query 1053 ---EYYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKF 1108 +VR W APE +++ + + +D+WS G+ EL T P Sbjct 270 GDLSRQKVRHTFVGTPCWMAPEVMEQVQGYDFKADIWSLGILAIELATGTAPYHKYP-PM 328 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 L+ Q L ER + L+++C + + + RPT L+ Sbjct 329 KVLMLTLQNDPPTLET-----NAERKDQYKAYGKSFKTLIRDCLQKDPAKRPTASELLKY 383 Score = 153 bits (386), Expect = 2e-37, Method: Composition-based stats. Identities = 47/264 (18%), Positives = 87/264 (33%), Gaps = 43/264 (16%) Query 638 RVVLKVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLD 696 +V +K ++ + MSQ +H ++ + + E +V + G + Sbjct 133 KVAIKCINLEKCQTSVDELSHEIQAMSQCNHPNVVSYYTSFIAQEELWVVMRLLNCGSML 192 Query 697 VWLRR----------ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLG 746 L+R + G + V +++ L Y +H ++ NILLA G Sbjct 193 DILKRKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEYFHLNGQIHRDIKAGNILLADDG 252 Query 747 LAEGTSPFIKLSDPG-----------VGLGALSREERVERIPWLAPECLPGGANSLSTAM 795 I+++D G + + R V W+APE + Sbjct 253 -------TIQIADFGVSGWLASSGGDLSRQKV-RHTFVGTPCWMAPEVMEQ-VQGYDFKA 303 Query 796 DKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-----------QHRLPEPSCPQLATL 844 D W G +E+ G AP P + + + + TL Sbjct 304 DIWSLGILAIELA-TGTAPYHKYPPMKVLMLTLQNDPPTLETNAERKDQYKAYGKSFKTL 362 Query 845 TSQCLTYEPTQRPSFRTILRDLTR 868 CL +P +RP+ +L+ Sbjct 363 IRDCLQKDPAKRPTASELLKYSFF 386 >sp|Q9Y2K2|SIK3_HUMAN Serine/threonine-protein kinase SIK3 OS=Homo sapiens OX=9606 GN=SIK3 PE=1 SV=4 Length=1321 Score = 224 bits (572), Expect = 2e-58, Method: Composition-based stats. Identities = 71/293 (24%), Positives = 120/293 (41%), Gaps = 29/293 (10%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADC 936 P + P Y + R +G+G+F V T+ T VA+K + K Sbjct 47 QPRPPAPASRGPMPARIGYYEIDRTIGKGNFAVVK----RATHLVTKAKVAIKIIDKTQL 102 Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SI 995 ++ +E+ I++ L H HII+ E E+ + LV EY G + D+L H + Sbjct 103 DEENLKKIFREVQIMKMLCHPHIIRLYQVME--TERMIYLVTEYASGGEIFDHLVAHGRM 160 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 + +QI + + H ++ +HRDL A N+LLD + +KI DFG + G Sbjct 161 AEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPG---Q 217 Query 1056 RVREDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 ++ SP + APE + ++ D+WS GV LY L+ Sbjct 218 LLKTWCGSPP-YAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFD------------ 264 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 T+ L + G + P E HL+++ + + R + E + Sbjct 265 ---GSTLQNLRARVLSG-KFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICK 313 Score = 176 bits (447), Expect = 2e-43, Method: Composition-based stats. Identities = 52/292 (18%), Positives = 95/292 (33%), Gaps = 42/292 (14%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 R+ EI +G+G V V + +V +K Sbjct 62 RIGYYEID--RTIGKGNFAVVKRATHLV------------------------TKAKVAIK 95 Query 643 VLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 ++D + + + +M + H H+ ++ V +VTEY G + L Sbjct 96 IIDKTQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLV 155 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G + +Q+ +A+ + +N+VH ++ N+LL + IK++D Sbjct 156 AH-GRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLD-------ANLNIKIADF 207 Query 761 GVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 G + P+ APE G +D W G L + G P Sbjct 208 GFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYD-GPKVDIWSLGVVLY-VLVCGALPFDG 265 Query 818 RSPSEKE-HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + + R+P + L L +P +R S I + Sbjct 266 STLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWM 317 >sp|P11440|CDK1_MOUSE Cyclin-dependent kinase 1 OS=Mus musculus OX=10090 GN=Cdk1 PE=1 SV=3 Length=297 Score = 206 bits (525), Expect = 2e-58, Method: Composition-based stats. Identities = 66/307 (21%), Positives = 124/307 (40%), Gaps = 38/307 (12%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ Sbjct 1 MEDYIKIEKIGEGTYGVV----YKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQIC 1008 L H +I+ + + L L+ E++ + L+ YL P + + + + QI Sbjct 57 ELRHPNIVSLQDVLMQ--DSRLYLIFEFLSM-DLKKYLDSIPPGQFMDSSLVKSYLHQIL 113 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +G+ + H++ +HRDL +N+L+D+ +K+ DFGLA+A RV +++ Sbjct 114 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP---IRVYTHEVVTLWYR 170 Query 1069 APECLKEY-KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 +PE L ++ D+WS G EL T + Sbjct 171 SPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPE 230 Query 1128 LE--RGERLPRPDKCPCEVY-----------HLMKNCWETEASFR---------PTFENL 1165 +E + + P P + L+ + + R P F++L Sbjct 231 VESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDL 290 Query 1166 IPILKTV 1172 +K + Sbjct 291 DNQIKKM 297 Score = 164 bits (414), Expect = 1e-43, Method: Composition-based stats. Identities = 43/267 (16%), Positives = 94/267 (35%), Gaps = 41/267 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ ++ +G+GT VY+GR RV G V +K + Sbjct 1 MEDYIKIEKIGEGTYGVVYKGRHRVTGQ------------------------IVAMKKIR 36 Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702 + + SL+ ++ H ++ + V ++ ++ E++ L +L Sbjct 37 LESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95 Query 703 RGHV-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 G + Q+ + + ++ ++H ++ +N+L+ G IKL+D G Sbjct 96 PGQFMDSSLVKSYLHQILQGIVFCHSRRVLHRDLKPQNLLIDDKG-------TIKLADFG 148 Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + V + + +PE L G+ ST +D W G E+ Sbjct 149 LARAFGIPIRVYTHEVVTLWYRSPEVLL-GSARYSTPVDIWSIGTIFAELATKKPLFHGD 207 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ P++ +L Sbjct 208 SEIDQLFRIFRALGTPNNEVWPEVESL 234 >sp|P51958|CDK1_CARAU Cyclin-dependent kinase 1 OS=Carassius auratus OX=7957 GN=cdk1 PE=1 SV=1 Length=302 Score = 207 bits (526), Expect = 2e-58, Method: Composition-based stats. Identities = 64/282 (23%), Positives = 110/282 (39%), Gaps = 29/282 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHII 960 +GEG +G V Y N TG++VA+K ++ + + S +EI +L+ L H +++ Sbjct 9 KIGEGTYGVV----YKGRNKTTGQVVAMKKIRLESEEEGVPSTAVREISLLKELQHPNVV 64 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS----IGLAQLLLFAQQICEGMAYLHA 1016 + E L LV E++ + L+ YL + + + QI EG+ + H Sbjct 65 RLLDVLMQ--ESKLYLVFEFLSM-DLKKYLDSIPSGQFMDPMLVKSYLYQILEGILFCHC 121 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE- 1075 + +HRDL +N+L+DN ++K+ DFGLA+A RV +++ APE L Sbjct 122 RRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVP---VRVYTHEVVTLWYRAPEVLLGA 178 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE--RGER 1133 ++ DVWS G EL T + +E + Sbjct 179 SRYSTPVDVWSIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNEVWPDVESLPDYK 238 Query 1134 LPRPDKCPCEVY-----------HLMKNCWETEASFRPTFEN 1164 P + L+ + R + Sbjct 239 NTFPKWKSGNLASTVKNLDKNGIDLLTKMLIYDPPKRISARQ 280 Score = 166 bits (421), Expect = 2e-44, Method: Composition-based stats. Identities = 44/267 (16%), Positives = 93/267 (35%), Gaps = 41/267 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + ++ +G+GT VY+GR + G V +K + Sbjct 1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQ------------------------VVAMKKIR 36 Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702 + + SL+ ++ H ++ + V ++ + +V E++ L +L Sbjct 37 LESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSM-DLKKYLDSIP 95 Query 703 RGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 G + Q+ + + + ++H ++ +N+L+ G+ IKL+D G Sbjct 96 SGQFMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLIDNKGV-------IKLADFG 148 Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + V + + APE L GA+ ST +D W G E+ Sbjct 149 LARAFGVPVRVYTHEVVTLWYRAPEVLL-GASRYSTPVDVWSIGTIFAELATKKPLFHGD 207 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ P + +L Sbjct 208 SEIDQLFRIFRTLGTPNNEVWPDVESL 234 >sp|Q7XQP4|SAPK7_ORYSJ Serine/threonine-protein kinase SAPK7 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK7 PE=2 SV=2 Length=359 Score = 209 bits (531), Expect = 2e-58, Method: Composition-based stats. Identities = 69/268 (26%), Positives = 105/268 (39%), Gaps = 26/268 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 D+G G+FG L N T E+VA+K + G + +EI R+L H +II+ Sbjct 9 DIGAGNFGVARLM----RNKETKELVAMKYIPR--GLKIDENVAREIINHRSLRHPNIIR 62 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 +K L +VMEY G L D + + F QQ+ G++Y H Sbjct 63 FKEVVVTPTH--LAIVMEYAAGGELFDRICNAGRFSEDEARYFFQQLICGVSYCHFMQIC 120 Query 1021 HRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N LLD +KI DFG +K + + + APE L ++ Sbjct 121 HRDLKLENTLLDGSPAPRLKICDFGYSK----SSLLHSKPKSTVGTPAYIAPEVLSRREY 176 Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 +DVWS GVTLY +L + P I + ++ E + Sbjct 177 DGKTADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIMSIQYKIPEYV--------- 227 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENL 1165 + L+ + + R T + Sbjct 228 -HVSQDCRQLLSRIFVANPAKRITIREI 254 Score = 154 bits (389), Expect = 1e-39, Method: Composition-based stats. Identities = 54/318 (17%), Positives = 86/318 (27%), Gaps = 41/318 (13%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + L +G G R++ + V +K + Sbjct 1 MERYELLKDIGAGNFG------------------------VARLMRNKETKELVAMKYI- 35 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 P I + H ++ V V +V EY G L + G Sbjct 36 PRGLKIDENVAREIINHRSLRHPNIIRFKEVVVTPTHLAIVMEYAAGGELFDRI-CNAGR 94 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 QQL +SY + H ++ N LL +P +K+ D G Sbjct 95 FSEDEARYFFQQLICGVSYCHFMQICHRDLKLENTLLD-----GSPAPRLKICDFGYSKS 149 Query 766 AL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 +L + V ++APE L T D W G TL + P Sbjct 150 SLLHSKPKSTVGTPAYIAPEVLSRREYDGKT-ADVWSCGVTLYVMLVGAYPFEDPDDPKN 208 Query 823 KEH----FYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 Q+++PE L S+ P +R + R I L+ Sbjct 209 FRKTIGRIMSIQYKIPEYVHVSQDCRQLLSRIFVANPAKRITIREIRNHPWFLKNLPREL 268 Query 877 VLTVNPDSPASDPTVFHK 894 D + Sbjct 269 TEAAQAMYYKKDNSAPTY 286 >sp|Q94A06|M2K1_ARATH Mitogen-activated protein kinase kinase 1 OS=Arabidopsis thaliana OX=3702 GN=MKK1 PE=1 SV=2 Length=354 Score = 209 bits (531), Expect = 2e-58, Method: Composition-based stats. Identities = 58/287 (20%), Positives = 112/287 (39%), Gaps = 21/287 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G G V L + T + A+K ++ + QE+ I + +++ Sbjct 74 IGKGSSGNVQLV----KHKLTQQFFALKVIQLNTEESTCRAISQELRINLSSQCPYLVSC 129 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHA-QHYI 1020 G + +++E++ GSL D L + + L +++ G+ Y+H + I Sbjct 130 YQSFYHNG--LVSIILEFMDGGSLADLLKKVGKVPENMLSAICKRVLRGLCYIHHERRII 187 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDL N+L+++ VKI DFG++K + + + +PE + + Sbjct 188 HRDLKPSNLLINHRGEVKITDFGVSKIL---TSTSSLANSFVGTYPYMSPERISGSLYSN 244 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK- 1139 SD+WS G+ L E T P K +G +V L + + P Sbjct 245 KSDIWSLGLVLLECATGKFPYTPPEHK--------KGWSSVYELVDAIVENPPPCAPSNL 296 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP-ILKTVHEKYQGQAPSVFS 1185 E + C + + R + + L+ + E + F+ Sbjct 297 FSPEFCSFISQCVQKDPRDRKSAKELLEHKFVKMFEDSDTNLSAYFT 343 Score = 161 bits (408), Expect = 4e-42, Method: Composition-based stats. Identities = 53/302 (18%), Positives = 105/302 (35%), Gaps = 51/302 (17%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +++ ++ + +G+G+ NV + + + L Sbjct 61 NQLSLADLEVIKVIGKGSSGNV------------------------QLVKHKLTQQFFAL 96 Query 642 KVLDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 KV+ + + A + + +L + ++ E+++ G L L+ Sbjct 97 KVIQLNTEESTCRAISQELRINLSSQCPYLVSCYQSFYHNGLVSIILEFMDGGSLADLLK 156 Query 701 RERGHVPMAWKMVVAQQLASALSYLE-NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + G VP + +++ L Y+ + ++H ++ N+L+ G +K++D Sbjct 157 KV-GKVPENMLSAICKRVLRGLCYIHHERRIIHRDLKPSNLLINHRGE-------VKITD 208 Query 760 PGVGLGALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 GV S V P+++PE + G S D W G LLE C G+ P Sbjct 209 FGVSKILTSTSSLANSFVGTYPYMSPERISGSL--YSNKSDIWSLGLVLLE-CATGKFPY 265 Query 816 QSRSP----SEKEHFYQRQHRLPEPS------CPQLATLTSQCLTYEPTQRPSFRTILRD 865 S P P P+ + SQC+ +P R S + +L Sbjct 266 TPPEHKKGWSSVYELVDAIVENPPPCAPSNLFSPEFCSFISQCVQKDPRDRKSAKELLEH 325 Query 866 LT 867 Sbjct 326 KF 327 >sp|Q8C0Q4|NEK11_MOUSE Serine/threonine-protein kinase Nek11 OS=Mus musculus OX=10090 GN=Nek11 PE=2 SV=2 Length=628 Score = 216 bits (551), Expect = 2e-58, Method: Composition-based stats. Identities = 67/306 (22%), Positives = 120/306 (39%), Gaps = 28/306 (9%) Query 868 RLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMV 927 L+ A + P PT R + LG G FG V L G V Sbjct 1 MLKFQETAKCVGRRPTVIPMYPTALIARRYVLQQKLGSGSFGTVYLVSDKKAKPGEELKV 60 Query 928 AVKALKA-DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSL 986 +K + + P E +L L+H I+++ +Q ++ ++ EY L Sbjct 61 -LKEISVGELNPNETVQANVEAQLLSRLHHPAIVRFHASFMEQ--ETFCIITEYCEGRDL 117 Query 987 RDYLPRHS-----IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGD 1041 + + Q++ + Q+ G+ Y+H + +HRDL ++N+ L N+ +KIGD Sbjct 118 DYRIQEYKEAGKVFAENQIVEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNNL-LKIGD 176 Query 1042 FGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 FG+++ + E + +PE LK + SD+WS LYE+ Sbjct 177 FGVSRLLMGSCELATTLT---GTPHYMSPEALKHQGYDAKSDIWSLACILYEMC------ 227 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + A + L + + G+ PD+ P E+ +M+ S RP+ Sbjct 228 ---------CLDHAFAGSSFLSVVLNIVEGKTPSLPDRYPRELNTIMERMLNKSPSLRPS 278 Query 1162 FENLIP 1167 +++ Sbjct 279 AADILK 284 Score = 170 bits (430), Expect = 8e-43, Method: Composition-based stats. Identities = 55/307 (18%), Positives = 100/307 (33%), Gaps = 37/307 (12%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 LG G+ VY + + PG + + + L+P+ + Sbjct 35 KLGSGSFGTVY----------------LVSDKKAKPGEELKVLKEISVGELNPNET---V 75 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER---GHVPMAW 710 A L+S++ H + H + ++TEY E LD ++ + Sbjct 76 QANVEAQLLSRLHHPAIVRFHASFMEQETFCIITEYCEGRDLDYRIQEYKEAGKVFAENQ 135 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR- 769 + QL + Y+ + ++H ++ +NI L L K+ D GV + Sbjct 136 IVEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNNLL--------KIGDFGVSRLLMGSC 187 Query 770 ---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 +++PE L D W L E+C A S S + Sbjct 188 ELATTLTGTPHYMSPEALKH--QGYDAKSDIWSLACILYEMCCLDHAFAGSSFLSVVLNI 245 Query 827 YQ-RQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885 + + LP+ +L T+ + L P+ RPS IL+ + L Sbjct 246 VEGKTPSLPDRYPRELNTIMERMLNKSPSLRPSAADILKAPYMEEQLQLLMCKYPEMTLE 305 Query 886 ASDPTVF 892 + Sbjct 306 DKNSVCQ 312 >sp|P05986|KAPC_YEAST cAMP-dependent protein kinase type 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TPK3 PE=1 SV=2 Length=398 Score = 210 bits (534), Expect = 2e-58, Method: Composition-based stats. Identities = 71/321 (22%), Positives = 121/321 (38%), Gaps = 34/321 (11%) Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901 ++ +C + P + + + + ++ + + +R Sbjct 36 HSVHEECSSNTPVEINGRNS---GKLKEEASAGICLVKKPMLQYRDTSGKYSLSDFQILR 92 Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHI 959 LG G FG+V L ++ G A+K LK + E +L + H I Sbjct 93 TLGTGSFGRVHLI----RSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFI 148 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQH 1018 I+ G +D + + +VM+Y+ G L L + +A ++C + YLH++ Sbjct 149 IRMWGTFQDS--QQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKD 206 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 I+RDL N+LLD + +KI DFG AK VP+ V + APE + + Sbjct 207 IIYRDLKPENILLDKNGHIKITDFGFAKYVPD------VTYTLCGTPDYIAPEVVSTKPY 260 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 + D WSFGV +YE+L T+ +L L P Sbjct 261 NKSVDWWSFGVLIYEMLAGYTPF--------------YNSNTMKTYENIL--NAELKFPP 304 Query 1139 KCPCEVYHLMKNCWETEASFR 1159 + L+K + S R Sbjct 305 FFHPDAQDLLKKLITRDLSER 325 Score = 176 bits (446), Expect = 1e-46, Method: Composition-based stats. Identities = 58/322 (18%), Positives = 112/322 (35%), Gaps = 41/322 (13%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + L LG G+ V+ +R +G K + V LK ++ Sbjct 86 SDFQILRTLGTGSFGRVH--LIRSNHNGRFYALKTLK-----------KHTIVKLKQVEH 132 Query 647 SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHV 706 ++ + ++S VSH + + G + MV +Y+E G L LR+ + Sbjct 133 TNDERR--------MLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQ-RF 183 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 P A ++ AL YL +K++++ ++ NILL + G IK++D G Sbjct 184 PNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNG-------HIKITDFGFAKYV 236 Query 767 LSREER-VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 ++APE + + ++D W FG + E+ S + E+ Sbjct 237 PDVTYTLCGTPDYIAPEVVST--KPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYEN 294 Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885 + + P P L + +T + + L LQ + + Sbjct 295 ILNAELKFPPFFHPDAQDLLKKLITRD---------LSERLGNLQNGSEDVKNHPWFNEV 345 Query 886 ASDPTVFHKRYLKKIRDLGEGH 907 + + + +G Sbjct 346 IWEKLLARYIETPYEPPIQQGQ 367 >sp|Q8TGA9|HOG1_BLUGR Mitogen-activated protein kinase HOG1 OS=Blumeria graminis OX=34373 GN=HOG1 PE=3 SV=1 Length=357 Score = 209 bits (531), Expect = 2e-58, Method: Composition-based stats. Identities = 66/276 (24%), Positives = 107/276 (39%), Gaps = 29/276 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V ++ TG+ VAVK + K P +E+ +L+ L HE++ Sbjct 24 QPVGMGAFGLVC----SAKDNLTGQNVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENV 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIHTIASENTLRFVQ 251 Query 1127 LLERGERLPRPD---KCPCEVYHLMKNCWETEASFR 1159 L + R P D L++ + R Sbjct 252 SLPKRVRQPLKDKFTNADPLAIGLLEEMLVFDPRRR 287 Score = 132 bits (331), Expect = 6e-32, Method: Composition-based stats. Identities = 40/252 (16%), Positives = 81/252 (32%), Gaps = 21/252 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E D + M + +D V +K ++ P ++ Y Sbjct 10 FGTTFE---ITSRYSDLQPVGMGAFGLVCSAKDNLTGQNVAVKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLRHENVISLSDIFISPLEDIYFVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILVNE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 + APE + +D W G E+ +G+ + F L Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-EGKPLFPGKDH--VNQFSIITELLGT 232 Query 836 PSCPQLATLTSQ 847 P + T+ S+ Sbjct 233 PPDDVIHTIASE 244 >sp|Q9FRS6|PXL1_ARATH Leucine-rich repeat receptor-like protein kinase PXL1 OS=Arabidopsis thaliana OX=3702 GN=PXL1 PE=1 SV=1 Length=1029 Score = 223 bits (568), Expect = 2e-58, Method: Composition-based stats. Identities = 69/296 (23%), Positives = 117/296 (40%), Gaps = 30/296 (10%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-----------SGW 944 ++K+ +G G G V T VAVK L PQ+ Sbjct 713 HIKESNIIGMGAIGIVYKAEVMRRPLLT---VAVKKLWRSPSPQNDIEDHHQEEDEEDDI 769 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-----GLAQ 999 +E+++L L H +I+K G E+ + +V EY+P G+L L Sbjct 770 LREVNLLGGLRHRNIVKILGYV--HNEREVMMVYEYMPNGNLGTALHSKDEKFLLRDWLS 827 Query 1000 LLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR 1056 A + +G+ YLH IHRD+ + N+LLD++ +I DFGLAK + +E Sbjct 828 RYNVAVGVVQGLNYLHNDCYPPIIHRDIKSNNILLDSNLEARIADFGLAKMMLHKNETVS 887 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQ 1116 + + APE K SD++S GV L EL+T ++++ + Sbjct 888 M---VAGSYGYIAPEYGYTLKIDEKSDIYSLGVVLLELVTGKMPIDPSFEDSIDVVEWIR 944 Query 1117 GQMTVLR-LTELLERGERLPRPDKCPCEV--YHLMKNCWETEASFRPTFENLIPIL 1169 ++ L E+++ + + C RP+ ++I +L Sbjct 945 RKVKKNESLEEVIDASIAGDCKHVIEEMLLALRIALLCTAKLPKDRPSIRDVITML 1000 Score = 180 bits (456), Expect = 1e-44, Method: Composition-based stats. Identities = 50/274 (18%), Positives = 93/274 (34%), Gaps = 55/274 (20%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-- 644 I + + +G G VY+ + R L V +K L Sbjct 712 SHIKESNIIGMGAIGIVYKAEV-----------------------MRRPLLTVAVKKLWR 748 Query 645 DPSHHD----------IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGP 694 PS + +L+ + H ++ + G E +MV EY+ +G Sbjct 749 SPSPQNDIEDHHQEEDEEDDILREVNLLGGLRHRNIVKILGYVHNEREVMMVYEYMPNGN 808 Query 695 LDVWLRRERGHV---PMAWKMVVAQQLASALSYLENK---NLVHGNVCGRNILLARLGLA 748 L L + + VA + L+YL N ++H ++ NILL Sbjct 809 LGTALHSKDEKFLLRDWLSRYNVAVGVVQGLNYLHNDCYPPIIHRDIKSNNILLD----- 863 Query 749 EGTSPFIKLSDPGVGLGALSREERV----ERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 ++ +++D G+ L + E V ++APE G + D + G L Sbjct 864 --SNLEARIADFGLAKMMLHKNETVSMVAGSYGYIAPEY--GYTLKIDEKSDIYSLGVVL 919 Query 805 LEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSC 838 LE+ G+ P+ + + ++ + Sbjct 920 LELV-TGKMPIDPSFEDSIDVVEWIRRKVKKNES 952 >sp|Q9SMQ4|SRK2F_ARATH Serine/threonine-protein kinase SRK2F OS=Arabidopsis thaliana OX=3702 GN=SRK2F PE=1 SV=1 Length=350 Score = 208 bits (530), Expect = 2e-58, Method: Composition-based stats. Identities = 71/276 (26%), Positives = 111/276 (40%), Gaps = 26/276 (9%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 +RDLG G+FG L GE AVK + + G + ++EI R Sbjct 1 MERYDILRDLGSGNFGVAKLV----REKANGEFYAVKYI--ERGLKIDEHVQREIINHRD 54 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMA 1012 L H +II++K L +VMEY G L + + + + +Q+ G++ Sbjct 55 LKHPNIIRFKEVFVTPTH--LAIVMEYAAGGELFERICNAGRFSEDEGRYYFKQLISGVS 112 Query 1013 YLHAQHYIHRDLAARNVLLDN--DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 Y HA HRDL N LLD +KI DFG +K + + + +P + AP Sbjct 113 YCHAMQICHRDLKLENTLLDGSPSSHLKICDFGYSK---SSVLHSQPKSTVGTPA-YVAP 168 Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E L ++ +DVWS GVTLY +L + P + + +L Sbjct 169 EVLSRKEYNGKIADVWSCGVTLYVMLVGAYPFEDPED----------PRNIRNTIQRILS 218 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 +P + E HL+ + + R T + Sbjct 219 VHYTIPDYVRISSECKHLLSRIFVADPDKRITVPEI 254 Score = 147 bits (370), Expect = 4e-37, Method: Composition-based stats. Identities = 52/327 (16%), Positives = 100/327 (31%), Gaps = 41/327 (13%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + L LG G V + +R + +G+ +K ++ Sbjct 1 MERYDILRDLGSGNFG-VAK-LVREKANGEFY----------------------AVKYIE 36 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 I + H ++ V V +V EY G L + G Sbjct 37 RG-LKIDEHVQREIINHRDLKHPNIIRFKEVFVTPTHLAIVMEYAAGGELFERI-CNAGR 94 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 +QL S +SY + H ++ N LL S +K+ D G Sbjct 95 FSEDEGRYYFKQLISGVSYCHAMQICHRDLKLENTLLD-----GSPSSHLKICDFGYSKS 149 Query 766 AL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 ++ + V ++APE L + D W G TL + P Sbjct 150 SVLHSQPKSTVGTPAYVAPEVLSRKEYN-GKIADVWSCGVTLYVMLVGAYPFEDPEDPRN 208 Query 823 KEHFYQR----QHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 + QR + +P+ + L S+ +P +R + I + L+ + Sbjct 209 IRNTIQRILSVHYTIPDYVRISSECKHLLSRIFVADPDKRITVPEIEKHPWFLKGPLVVP 268 Query 877 VLTVNPDSPASDPTVFHKRYLKKIRDL 903 D+ + ++ + + ++ Sbjct 269 PEEEKCDNGVEEEEEEEEKCRQSVEEI 295 >sp|Q60DG4|NEK4_ORYSJ Serine/threonine-protein kinase Nek4 OS=Oryza sativa subsp. japonica OX=39947 GN=NEK4 PE=2 SV=1 Length=943 Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats. Identities = 61/282 (22%), Positives = 116/282 (41%), Gaps = 28/282 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEI 948 + + +G G FG L + +K ++ A + R QE+ Sbjct 1 MESRMDQYEIMEQVGRGAFGAAILVNHKIERK----KYVLKKIRLARQTERCRKSAHQEM 56 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQ 1005 ++ L H +I+++K ++G + +V Y G + + + + + +LL + Sbjct 57 ALIARLQHPYIVEFKEAWVEKG-CYVCIVTGYCEGGDMDELMKKLNGTYFPEEKLLKWFA 115 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 Q+ + YLH+ + +HRDL N+ L D+ +++GDFGLAK + E + Sbjct 116 QLVLAVDYLHSNYVLHRDLKCSNIFLTKDQDIRLGDFGLAKTLKEDD----LTSSVVGTP 171 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 + PE L + + + SD+WS G +YE+ ++ P K ++ G L Sbjct 172 NYMCPELLTDIPYGFKSDIWSLGCCMYEM-----AAHRPAFKAFDMAG----------LI 216 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + R P P + L+K+ RPT ++ Sbjct 217 SKINRSSIGPLPACYSSSMKTLIKSMLRKSPEHRPTASEILK 258 Score = 145 bits (367), Expect = 4e-34, Method: Composition-based stats. Identities = 56/327 (17%), Positives = 104/327 (32%), Gaps = 41/327 (13%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 R+DQ EI + +G+G ++ ++ V+ K Sbjct 4 RMDQYEI--MEQVGRGAFG-----------------------AAILVNHKIERKKYVLKK 38 Query 643 -VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLR 700 L + ++ +L++++ H ++ V +VT Y E G +D ++ Sbjct 39 IRLARQTERCRKSAHQEMALIARLQHPYIVEFKEAWVEKGCYVCIVTGYCEGGDMDELMK 98 Query 701 RERG-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + G + P + QL A+ YL + ++H ++ NI L + I+L D Sbjct 99 KLNGTYFPEEKLLKWFAQLVLAVDYLHSNYVLHRDLKCSNIFLTK-------DQDIRLGD 151 Query 760 PGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL- 815 G+ + V ++ PE L D W G + E+ A Sbjct 152 FGLAKTLKEDDLTSSVVGTPNYMCPELLTDIPYGF--KSDIWSLGCCMYEMAAHRPAFKA 209 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 + + LP + TL L P RP+ IL++ N Sbjct 210 FDMAGLISKINRSSIGPLPACYSSSMKTLIKSMLRKSPEHRPTASEILKNPYLQPYVNQC 269 Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRD 902 L+ P + Sbjct 270 RPLSDAPTPIRMPEKPLSTSRSNQRCT 296 >sp|Q0VD22|STK33_BOVIN Serine/threonine-protein kinase 33 OS=Bos taurus OX=9913 GN=STK33 PE=2 SV=1 Length=486 Score = 213 bits (541), Expect = 2e-58, Method: Composition-based stats. Identities = 69/325 (21%), Positives = 124/325 (38%), Gaps = 31/325 (10%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 PS + + Q + D + R LG+G FG V Sbjct 73 KDSPSKSSNIERKPSQQQWGRGNFTEGKVPHIRMDNGAALQEIYTFGRILGQGSFGMV-- 130 Query 914 YCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972 + + A+K + + G ++E+DIL+++ HEHII + E K Sbjct 131 --IEAIDKERETKWAIKKVNKEKAGSSAVKLLEREVDILKSVKHEHIIHLEQVFE--TPK 186 Query 973 SLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL 1031 + LVME G L++ L R + Q + +AYLH + +HRDL N+++ Sbjct 187 KMYLVMELCEDGELKEILERKGHFSENETRWIIQSLASAIAYLHNKDIVHRDLKLENIMV 246 Query 1032 DN---------DRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082 + + +K+ DFGLA G ++ +P+ + APE + + + Sbjct 247 KSSFIDANNEMNLNIKVTDFGLA-VKKHGRSEVMLQTTCGTPI-YMAPEVINAHDYSQQC 304 Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 D+WS GV +Y LL +A + + L + E + + Sbjct 305 DIWSIGVIMYILLCGKAPF------------MASSEEKLFELIKKGELHFKNSIWNSISD 352 Query 1143 EVYHLMKNCWETEASFRPTFENLIP 1167 ++K + + + R T + L+ Sbjct 353 CAKSVLKQLMKVDPAHRITAKELLD 377 Score = 186 bits (473), Expect = 2e-49, Method: Composition-based stats. Identities = 58/292 (20%), Positives = 107/292 (37%), Gaps = 42/292 (14%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH- 648 T LGQG+ V E D+ +E + +K ++ Sbjct 117 TFGRILGQGSFGMVIEAI------------------------DKERETKWAIKKVNKEKA 152 Query 649 -HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 ++ V H H+ + V + +V E E G L L R +GH Sbjct 153 GSSAVKLLEREVDILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILER-KGHFS 211 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG--TSPFIKLSDPGVGLG 765 + Q LASA++YL NK++VH ++ NI++ + + IK++D G+ + Sbjct 212 ENETRWIIQSLASAIAYLHNKDIVHRDLKLENIMVKSSFIDANNEMNLNIKVTDFGLAVK 271 Query 766 ALSRE-----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 R ++APE + A+ S D W G + I G+AP + S Sbjct 272 KHGRSEVMLQTTCGTPIYMAPEVI--NAHDYSQQCDIWSIGVIMY-ILLCGKAPFMASSE 328 Query 821 SEKEHFYQRQ-----HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + ++ + + ++ Q + +P R + + +L + Sbjct 329 EKLFELIKKGELHFKNSIWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQW 380 >sp|P21860|ERBB3_HUMAN Receptor tyrosine-protein kinase erbB-3 OS=Homo sapiens OX=9606 GN=ERBB3 PE=1 SV=1 Length=1342 Score = 224 bits (571), Expect = 2e-58, Method: Composition-based stats. Identities = 90/272 (33%), Positives = 139/272 (51%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + V +K ++ G Q + + +L H HI++ Sbjct 715 LGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRL 774 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C SLQLV +Y+PLGSL D++ +H +G LL + QI +GM YL + Sbjct 775 LGLC---PGSSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMV 831 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HR+LAARNVLL + V++ DFG+A +P + + + +P+ W A E + K+ + Sbjct 832 HRNLAARNVLLKSPSQVQVADFGVADLLPP-DDKQLLYSEAKTPIKWMALESIHFGKYTH 890 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + + + +LLE+GERL +P C Sbjct 891 QSDVWSYGVTVWELMTFG--------------AEPYAGLRLAEVPDLLEKGERLAQPQIC 936 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW + + RPTF+ L + Sbjct 937 TIDVYMVMVKCWMIDENIRPTFKELANEFTRM 968 Score = 206 bits (525), Expect = 8e-53, Method: Composition-based stats. Identities = 72/376 (19%), Positives = 136/376 (36%), Gaps = 39/376 (10%) Query 510 QDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARA 569 VL G ++ + + ++ G + R + L Sbjct 630 LGQTLVLIGKTHLTMALTVIAGLVVIFMMLGGTFLYWRGRRIQNKRAMRRYLERGESIEP 689 Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 + +++ + E+ +L LG G V++G EG Sbjct 690 LDPSEKANKVLARIFKETELRKLKVLGSGVFGTVHKGVWIPEGESI-------------- 735 Query 630 GRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ V +KV+ D S A + + + H H+ + G+C G +VT+ Sbjct 736 ------KIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCP-GSSLQLVTQ 788 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 Y+ G L +R+ RG + + Q+A + YLE +VH N+ RN+LL Sbjct 789 YLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLL------ 842 Query 749 EGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 + ++++D GV + E I W+A E + G + D W +G Sbjct 843 -KSPSQVQVADFGVADLLPPDDKQLLYSEAKTPIKWMALESIHFG--KYTHQSDVWSYGV 899 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860 T+ E+ G P +E ++ RL P+ + + +C + RP+F+ Sbjct 900 TVWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFK 959 Query 861 TILRDLTRLQPHNLAD 876 + + TR+ Sbjct 960 ELANEFTRMARDPPRY 975 >sp|P97477|AURKA_MOUSE Aurora kinase A OS=Mus musculus OX=10090 GN=Aurka PE=1 SV=1 Length=395 Score = 210 bits (534), Expect = 2e-58, Method: Composition-based stats. Identities = 65/296 (22%), Positives = 110/296 (37%), Gaps = 33/296 (11%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRS-GWKQEI 948 + R LG+G FG V L + ++A+K L K + ++E+ Sbjct 118 QWTLEDFDIGRPLGKGKFGNVYL----ARERQSKFILALKVLFKTQLEKANVEHQLRREV 173 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQI 1007 +I L H +I++ G D + L++EY PLG++ L + + + ++ Sbjct 174 EIQSHLRHPNILRLYGYFHDAT--RVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 231 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 ++Y H++ IHRD+ N+LL ++ +KI DFG + P R + + Sbjct 232 ANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSR-----RTTMCGTLDY 286 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 PE ++ D+WS GV YE L + A R Sbjct 287 LPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFE------------AHTYQETYRRISR 334 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183 +E PD L+ + AS R T + L+ K P Sbjct 335 VE----FTFPDFVTEGARDLISRLLKHNASQRLTLAEV---LEHPWIKANSSKPPT 383 Score = 179 bits (455), Expect = 6e-48, Method: Composition-based stats. Identities = 59/326 (18%), Positives = 111/326 (34%), Gaps = 41/326 (13%) Query 548 RRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGR 607 R PQ E + + ++ LG+G NVY Sbjct 83 SRLNNPQKNEQPAASGNDSEKEQASLQKTEDTKKRQWTLEDFDIGRPLGKGKFGNVYLA- 141 Query 608 LRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETASLMSQ 664 R+R + + LKVL + ++ + S Sbjct 142 -----------------------RERQSKFILALKVLFKTQLEKANVEHQLRREVEIQSH 178 Query 665 VSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSY 724 + H ++ ++G ++ EY G + L++ +LA+ALSY Sbjct 179 LRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKL-SKFDEQRTATYITELANALSY 237 Query 725 LENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--REERVERIPWLAPE 782 +K ++H ++ N+LL G++ +K++D G + A S R + +L PE Sbjct 238 CHSKRVIHRDIKPENLLL-------GSNGELKIADFGWSVHAPSSRRTTMCGTLDYLPPE 290 Query 783 CLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK-EHFYQRQHRLPEPSCPQL 841 + G + +D W G E G P ++ + E + + P+ Sbjct 291 MIEGRMH--DEKVDLWSLGVLCYEFLV-GMPPFEAHTYQETYRRISRVEFTFPDFVTEGA 347 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLT 867 L S+ L + +QR + +L Sbjct 348 RDLISRLLKHNASQRLTLAEVLEHPW 373 >sp|Q9WUA6|AKT3_MOUSE RAC-gamma serine/threonine-protein kinase OS=Mus musculus OX=10090 GN=Akt3 PE=1 SV=1 Length=479 Score = 213 bits (541), Expect = 2e-58, Method: Composition-based stats. Identities = 75/374 (20%), Positives = 129/374 (34%), Gaps = 51/374 (14%) Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTY-------------------- 851 E P P +F + +L + P+ T +CL + Sbjct 40 EKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWT 99 Query 852 ---EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 + R + + ++ D+ + ++ LG+G F Sbjct 100 EAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTF 159 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCC 966 GKV L +G+ A+K LK + + E +L+ H + K Sbjct 160 GKVILV----REKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSF 215 Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 Q + L VMEYV G L +L R + + +I + YLH+ ++RDL Sbjct 216 --QTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLK 273 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 N++LD D +KI DFGL K EG + + APE L++ + A D W Sbjct 274 LENLMLDKDGHIKITDFGLCK---EGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWW 330 Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 GV +YE++ + Q + L + + + P + Sbjct 331 GLGVVMYEMMCGRLPFYN------------QDHEKLFELILMED----IKFPRTLSSDAK 374 Query 1146 HLMKNCWETEASFR 1159 L+ + + R Sbjct 375 SLLSGLLIKDPNKR 388 Score = 163 bits (413), Expect = 1e-41, Method: Composition-based stats. Identities = 56/293 (19%), Positives = 96/293 (33%), Gaps = 43/293 (15%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 ++ S R + L LG+GT V + R Sbjct 131 EEMDASTTHHKRKTMNDFDYLKLLGKGTFGKV------------------------ILVR 166 Query 632 DRGQELRVVLKVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ +K+L + ++ H L + V E Sbjct 167 EKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVME 226 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 YV G L L RER ++ SAL YL + +V+ ++ N++L + G Sbjct 227 YVNGGELFFHLSRER-VFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDG-- 283 Query 749 EGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 IK++D G+ ++ + +LAPE L N A+D WG G + Sbjct 284 -----HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLED--NDYGRAVDWWGLGVVM 336 Query 805 LEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 E+ G P ++ + + P +L S L +P +R Sbjct 337 YEMMC-GRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKR 388 >sp|P23111|CDC2_MAIZE Cell division control protein 2 homolog OS=Zea mays OX=4577 GN=CDC2 PE=2 SV=1 Length=294 Score = 206 bits (525), Expect = 2e-58, Method: Composition-based stats. Identities = 72/295 (24%), Positives = 124/295 (42%), Gaps = 33/295 (11%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ Sbjct 1 MEQYEKVEKIGEGTYGVV----YKALDKATNETIALKKIRLEQEDEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009 + H +I++ EK + LV EY+ L L+ ++ P + + + QI Sbjct 57 EMNHGNIVRLHDVV--HSEKRIYLVFEYLDL-DLKKFMDSCPEFAKNPTLIKSYLYQILH 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 G+AY H+ +HRDL +N+L+D +K+ DFGLA+A R +++ Sbjct 114 GVAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIP---VRTFTHEVVTLWYR 170 Query 1069 APECLKE-YKFYYASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIGIAQGQMTVL 1122 APE L ++ DVWS G E++ DS K ++G Q + Sbjct 171 APEILLGARQYSTPVDVWSVGCIFAEMVNQKPLFPGDSEIDELFKIFRILGTPNEQ-SWP 229 Query 1123 RLTELLERGERLPR----------PDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 ++ L + PR P+ P + L+ E S R T + Sbjct 230 GVSCLPDFKTAFPRWQAQDLATVVPNLDPAGL-DLLSKMLRYEPSKRITARQALE 283 Score = 159 bits (402), Expect = 6e-42, Method: Composition-based stats. Identities = 47/266 (18%), Positives = 93/266 (35%), Gaps = 39/266 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 ++ ++ +G+GT VY+ D+ + LK Sbjct 1 MEQYEKVEKIGEGTYGVVYKAL------------------------DKATNETIALKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702 L+ + SL+ +++H ++ +H V +V EY++ L ++ Sbjct 37 LEQEDEGVPSTAIREISLLKEMNHGNIVRLHDVVHSEKRIYLVFEYLDL-DLKKFMDSCP 95 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 Q+ ++Y + ++H ++ +N+L+ R A +KL+D G+ Sbjct 96 EFAKNPTLIKSYLYQILHGVAYCHSHRVLHRDLKPQNLLIDRRTNA------LKLADFGL 149 Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + + APE L GA ST +D W G E+ Sbjct 150 ARAFGIPVRTFTHEVVTLWYRAPEILL-GARQYSTPVDVWSVGCIFAEMVNQKPLFPGDS 208 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844 E ++ E S P ++ L Sbjct 209 EIDELFKIFRILGTPNEQSWPGVSCL 234 >sp|Q9FF31|LRL21_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 2.1 OS=Arabidopsis thaliana OX=3702 GN=LRK10L-2.1 PE=3 SV=1 Length=638 Score = 217 bits (552), Expect = 2e-58, Method: Composition-based stats. Identities = 65/289 (22%), Positives = 115/289 (40%), Gaps = 33/289 (11%) Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 LG+G FG V N G VAVK LK + E+ + H + Sbjct 323 FSHTLGKGGFGTVYGG-----NLCDGRKVAVKILKDFKSNG--EDFINEVASMSQTSHVN 375 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLH 1015 I+ G C + +++ +V E++ GSL +L + ++ L A + G+ YLH Sbjct 376 IVSLLGFCYEGSKRA--IVYEFLENGSLDQFLSEKKSLNLDVSTLYRIALGVARGLDYLH 433 Query 1016 AQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 +H D+ +N+LLD+ K+ DFGLAK E E D + + APE Sbjct 434 HGCKTRIVHFDIKPQNILLDDTFCPKVSDFGLAKLC-EKRESILSLLDARGTIGYIAPEV 492 Query 1073 LKE--YKFYYASDVWSFGVTLYELL---------THCDSSQSPPTKFLELIGIAQGQMTV 1121 + + SDV+S+G+ + E++ T +S S + G+ T Sbjct 493 FSGMYGRVSHKSDVYSYGMLVLEMIGAKNKEIEETAASNSSSAYFPDWIYKNLENGEDTW 552 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 E+ + + ++ + C + RP ++ +++ Sbjct 553 KFGDEISREDK------EVAKKMTLVGLWCIQPSPLNRPPMNRIVEMME 595 Score = 212 bits (540), Expect = 6e-57, Method: Composition-based stats. Identities = 65/322 (20%), Positives = 112/322 (35%), Gaps = 62/322 (19%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 + L Q S+ V + LG+G VY G L Sbjct 306 VQLKQYSYAEVRKITKLFSHTLGKGGFGTVYGGNLCDGR--------------------- 344 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +V +K+L + F + MSQ SH ++ + G C G + +V E++E+G Sbjct 345 ----KVAVKILKDFKSNG-EDFINEVASMSQTSHVNIVSLLGFCYEGSKRAIVYEFLENG 399 Query 694 PLDVWLRRERG-HVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLARLGLAE 749 LD +L ++ ++ ++ +A +A L YL + +VH ++ +NILL Sbjct 400 SLDQFLSEKKSLNLDVSTLYRIALGVARGLDYLHHGCKTRIVHFDIKPQNILLDDTFCP- 458 Query 750 GTSPFIKLSDPGVGLGALSREERV------ERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 K+SD G+ RE + I ++APE G +S D + +G Sbjct 459 ------KVSDFGLAKLCEKRESILSLLDARGTIGYIAPEVFSGMYGRVSHKSDVYSYGML 512 Query 804 LLEIC---------------FDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLT--- 845 +LE+ P E + ++A Sbjct 513 VLEMIGAKNKEIEETAASNSSSAYFPDWIYKNLENGEDTWKFGDEISREDKEVAKKMTLV 572 Query 846 -SQCLTYEPTQRPSFRTILRDL 866 C+ P RP I+ + Sbjct 573 GLWCIQPSPLNRPPMNRIVEMM 594 >sp|Q9Y243|AKT3_HUMAN RAC-gamma serine/threonine-protein kinase OS=Homo sapiens OX=9606 GN=AKT3 PE=1 SV=1 Length=479 Score = 212 bits (540), Expect = 2e-58, Method: Composition-based stats. Identities = 75/374 (20%), Positives = 129/374 (34%), Gaps = 51/374 (14%) Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTY-------------------- 851 E P P +F + +L + P+ T +CL + Sbjct 40 EKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWT 99 Query 852 ---EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 + R + + ++ D+ + ++ LG+G F Sbjct 100 EAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTF 159 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCC 966 GKV L +G+ A+K LK + + E +L+ H + K Sbjct 160 GKVILV----REKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSF 215 Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 Q + L VMEYV G L +L R + + +I + YLH+ ++RDL Sbjct 216 --QTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLK 273 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 N++LD D +KI DFGL K EG + + APE L++ + A D W Sbjct 274 LENLMLDKDGHIKITDFGLCK---EGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWW 330 Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 GV +YE++ + Q + L + + + P + Sbjct 331 GLGVVMYEMMCGRLPFYN------------QDHEKLFELILMED----IKFPRTLSSDAK 374 Query 1146 HLMKNCWETEASFR 1159 L+ + + R Sbjct 375 SLLSGLLIKDPNKR 388 Score = 163 bits (413), Expect = 1e-41, Method: Composition-based stats. Identities = 56/293 (19%), Positives = 96/293 (33%), Gaps = 43/293 (15%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 ++ S R + L LG+GT V + R Sbjct 131 EEMDASTTHHKRKTMNDFDYLKLLGKGTFGKV------------------------ILVR 166 Query 632 DRGQELRVVLKVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ +K+L + ++ H L + V E Sbjct 167 EKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVME 226 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 YV G L L RER ++ SAL YL + +V+ ++ N++L + G Sbjct 227 YVNGGELFFHLSRER-VFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDG-- 283 Query 749 EGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 IK++D G+ ++ + +LAPE L N A+D WG G + Sbjct 284 -----HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLED--NDYGRAVDWWGLGVVM 336 Query 805 LEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 E+ G P ++ + + P +L S L +P +R Sbjct 337 YEMMC-GRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKR 388 >sp|Q5RB22|ERBB3_PONAB Receptor tyrosine-protein kinase erbB-3 OS=Pongo abelii OX=9601 GN=ERBB3 PE=2 SV=1 Length=1342 Score = 224 bits (571), Expect = 3e-58, Method: Composition-based stats. Identities = 90/272 (33%), Positives = 139/272 (51%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + V +K ++ G Q + + +L H HI++ Sbjct 715 LGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRL 774 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C SLQLV +Y+PLGSL D++ +H +G LL + QI +GM YL + Sbjct 775 LGLC---PGSSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMV 831 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HR+LAARNVLL + V++ DFG+A +P + + + +P+ W A E + K+ + Sbjct 832 HRNLAARNVLLKSPSQVQVADFGVADLLPP-DDKQLLYSEAKTPIKWMALESIHFGKYTH 890 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + + + +LLE+GERL +P C Sbjct 891 QSDVWSYGVTVWELMTFG--------------AEPYAGLRLAEVPDLLEKGERLAQPQIC 936 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW + + RPTF+ L + Sbjct 937 TIDVYMVMVKCWMIDENIRPTFKELANEFTRM 968 Score = 206 bits (524), Expect = 1e-52, Method: Composition-based stats. Identities = 72/376 (19%), Positives = 136/376 (36%), Gaps = 39/376 (10%) Query 510 QDGAFVLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARA 569 VL G ++ + + ++ G + R + L Sbjct 630 LGQTLVLIGKTHLTMALTVIAGLVVIFMMLGGTFLYWRGRRIQNKRAMRRYLERGESIEP 689 Query 570 SPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVP 629 + +++ + E+ +L LG G V++G EG Sbjct 690 LDPSEKANKVLARIFKETELKKLKVLGSGVFGTVHKGVWIPEGESI-------------- 735 Query 630 GRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ V +KV+ D S A + + + H H+ + G+C G +VT+ Sbjct 736 ------KIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCP-GSSLQLVTQ 788 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 Y+ G L +R+ RG + + Q+A + YLE +VH N+ RN+LL Sbjct 789 YLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLL------ 842 Query 749 EGTSPFIKLSDPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGA 802 + ++++D GV + E I W+A E + G + D W +G Sbjct 843 -KSPSQVQVADFGVADLLPPDDKQLLYSEAKTPIKWMALESIHFG--KYTHQSDVWSYGV 899 Query 803 TLLEICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFR 860 T+ E+ G P +E ++ RL P+ + + +C + RP+F+ Sbjct 900 TVWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFK 959 Query 861 TILRDLTRLQPHNLAD 876 + + TR+ Sbjct 960 ELANEFTRMARDPPRY 975 >sp|Q63484|AKT3_RAT RAC-gamma serine/threonine-protein kinase OS=Rattus norvegicus OX=10116 GN=Akt3 PE=2 SV=2 Length=479 Score = 212 bits (540), Expect = 3e-58, Method: Composition-based stats. Identities = 75/374 (20%), Positives = 129/374 (34%), Gaps = 51/374 (14%) Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTY-------------------- 851 E P P +F + +L + P+ T +CL + Sbjct 40 EKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWT 99 Query 852 ---EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 + R + + ++ D+ + ++ LG+G F Sbjct 100 EAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTF 159 Query 909 GKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYKGCC 966 GKV L +G+ A+K LK + + E +L+ H + K Sbjct 160 GKVILV----REKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSF 215 Query 967 EDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLA 1025 Q + L VMEYV G L +L R + + +I + YLH+ ++RDL Sbjct 216 --QTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLK 273 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVW 1085 N++LD D +KI DFGL K EG + + APE L++ + A D W Sbjct 274 LENLMLDKDGHIKITDFGLCK---EGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWW 330 Query 1086 SFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVY 1145 GV +YE++ + Q + L + + + P + Sbjct 331 GLGVVMYEMMCGRLPFYN------------QDHEKLFELILMED----IKFPRTLSSDAK 374 Query 1146 HLMKNCWETEASFR 1159 L+ + + R Sbjct 375 SLLSGLLIKDPNKR 388 Score = 163 bits (412), Expect = 2e-41, Method: Composition-based stats. Identities = 56/293 (19%), Positives = 96/293 (33%), Gaps = 43/293 (15%) Query 572 RTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGR 631 ++ S R + L LG+GT V + R Sbjct 131 EEMDASTTHHKRKTMNDFDYLKLLGKGTFGKV------------------------ILVR 166 Query 632 DRGQELRVVLKVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 ++ +K+L + ++ H L + V E Sbjct 167 EKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVME 226 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 YV G L L RER ++ SAL YL + +V+ ++ N++L + G Sbjct 227 YVNGGELFFHLSRER-VFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDG-- 283 Query 749 EGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 IK++D G+ ++ + +LAPE L N A+D WG G + Sbjct 284 -----HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLED--NDYGRAVDWWGLGVVM 336 Query 805 LEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 E+ G P ++ + + P +L S L +P +R Sbjct 337 YEMMC-GRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKR 388 >sp|Q76P07|Y7165_DICDI Probable serine/threonine-protein kinase DDB_G0277165 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0277165 PE=3 SV=1 Length=833 Score = 220 bits (561), Expect = 3e-58, Method: Composition-based stats. Identities = 71/282 (25%), Positives = 115/282 (41%), Gaps = 31/282 (11%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC---GPQHRSGWK 945 + + LG+G GKV L + TG V +K + + P R + Sbjct 1 MEIHSVGPFIIGKTLGQGTTGKVKLGFHK----DTGFKVGIKIINKELLINKPSMRRKIE 56 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFA 1004 +EI +++ + H + +K E K L L++EYV G L DYL + + + L F Sbjct 57 REIVLMKLIDHPNAMKMYEVYE--TSKYLFLILEYVEGGELFDYLVEKGGLESGEALFFF 114 Query 1005 QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 QQI G+ Y H+++ HRDL N+LL D+ +KI DFG+ V + + Sbjct 115 QQIIIGLEYCHSRNICHRDLKPENLLLSGDKRIKIADFGMGSIVRKDMLLHTS----CGS 170 Query 1065 VFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 + +PE + + +DVWS GV LY LLT + R Sbjct 171 PHYASPEVVSGIDYDGQKADVWSCGVILYALLTGKLPFDDE---------------NIRR 215 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 L ++ G P + L+ + S R + + + Sbjct 216 LLNKVKNGA-FSMPPYIHKDAQDLLTKMLTVDPSKRISIKEI 256 Score = 178 bits (452), Expect = 1e-44, Method: Composition-based stats. Identities = 61/331 (18%), Positives = 112/331 (34%), Gaps = 37/331 (11%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 LGQGT V G + G ++++ K L + Sbjct 9 FIIGKTLGQGTTGKVKLGFHKDTGFKVG--------------------IKIINKELLINK 48 Query 649 HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 + LM + H + ++ V ++ EYVE G L +L E+G + Sbjct 49 PSMRRKIEREIVLMKLIDHPNAMKMYEVYETSKYLFLILEYVEGGELFDYL-VEKGGLES 107 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LG 765 + QQ+ L Y ++N+ H ++ N+LL+ IK++D G+G Sbjct 108 GEALFFFQQIIIGLEYCHSRNICHRDLKPENLLLS-------GDKRIKIADFGMGSIVRK 160 Query 766 ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 + + +PE + G D W G L + G+ P + + Sbjct 161 DMLLHTSCGSPHYASPEVVSGIDYD-GQKADVWSCGVILYALL-TGKLPFDDENIRRLLN 218 Query 826 FYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884 + +P L ++ LT +P++R S + I + N T + Sbjct 219 KVKNGAFSMPPYIHKDAQDLLTKMLTVDPSKRISIKEIKEHPWFVSNFNQFQKATPVEEI 278 Query 885 PASD---PTVFHKRYLKKIRDLGEGHFGKVS 912 A + + + + LG G +V Sbjct 279 NAEPLVDYSQIDEDIFRSLMALGVGTIDEVK 309 >sp|O01798|SPE8_CAEEL Spermatocyte protein spe-8 OS=Caenorhabditis elegans OX=6239 GN=spe-8 PE=1 SV=2 Length=512 Score = 213 bits (542), Expect = 3e-58, Method: Composition-based stats. Identities = 56/239 (23%), Positives = 105/239 (44%), Gaps = 34/239 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +++ +++T LG+G V++G L+ P + V + Sbjct 210 WQLNNEQVTLNKKLGEGQFGEVHKGSLKTSVFAAP--------------------VTVAV 249 Query 642 KVLDPSH--HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 K L +H + + F A++M +SH ++ +GVC ++V E+ + L+ L Sbjct 250 KTLHQNHLSANEKILFLREANVMLTLSHPNVIKFYGVCTMKEPIMIVMEFCDGKSLEDAL 309 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 + V K++ A + YL K ++H ++ RN LL +K+SD Sbjct 310 LSKEEKVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNSK-------KILKISD 362 Query 760 PGVGLGALSREERVER---IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ + ++ +ER + ++APE L G STA D + +GA + E+ DG+ P Sbjct 363 FGLSVKGVAIKERKGGCLPVKYMAPETLKKGL--YSTASDIYSYGALMYEVYTDGKTPF 419 Score = 210 bits (535), Expect = 3e-57, Method: Composition-based stats. Identities = 76/321 (24%), Positives = 135/321 (42%), Gaps = 20/321 (6%) Query 854 TQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSL 913 + + H A + + + LGEG FG+V Sbjct 174 KKYAFKSICELIAYHKRNHKPIYEGMTLICGLARHGWQLNNEQVTLNKKLGEGQFGEVHK 233 Query 914 YCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK 972 + VAVK L + + + +E +++ TL H ++IK+ G C + + Sbjct 234 GSLKTSVFAAPVTVAVKTLHQNHLSANEKILFLREANVMLTLSHPNVIKFYGVCTMK--E 291 Query 973 SLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL 1030 + +VME+ SL D L + +L+ G+ YLH + IHRD+AARN L Sbjct 292 PIMIVMEFCDGKSLEDALLSKEEKVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCL 351 Query 1031 LDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVT 1090 L++ +++KI DFGL+ E R+ G PV + APE LK+ + ASD++S+G Sbjct 352 LNSKKILKISDFGLSVKGVAIKE----RKGGCLPVKYMAPETLKKGLYSTASDIYSYGAL 407 Query 1091 LYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKN 1150 +YE+ T + E G+ ++ + + + + P + ++ + Sbjct 408 MYEVYTDGKTP-------FETCGLRGNELRKAIIGKRISLAVEVELPVF----IANIFEQ 456 Query 1151 CWETEASFRPTFENLIPILKT 1171 + E R + + +I I K Sbjct 457 SRQYETEDRISSKQIIQIFKE 477 >sp|P48734|CDK1_BOVIN Cyclin-dependent kinase 1 OS=Bos taurus OX=9913 GN=CDK1 PE=2 SV=2 Length=297 Score = 206 bits (524), Expect = 3e-58, Method: Composition-based stats. Identities = 71/308 (23%), Positives = 130/308 (42%), Gaps = 40/308 (13%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ Sbjct 1 MEDYTKIEKIGEGTYGVV----YKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQIC 1008 L H +I+ + + L L+ E++ + L+ YL P + + + + QI Sbjct 57 ELRHPNIVSLQDVLMQ--DSRLYLIFEFLSM-DLKKYLDSIPPGQFMDSSLVKSYLYQIL 113 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +G+ + H++ +HRDL +N+L+D+ +K+ DFGLA+A RV +++ Sbjct 114 QGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP---IRVYTHEVVTLWYR 170 Query 1069 APECLKEY-KFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQMTVL 1122 +PE L ++ D+WS G EL T H DS + +G ++ Sbjct 171 SPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV-WP 229 Query 1123 RLTELLERGERLP--RPDKCPCEVY-------HLMKNCWETEASFR---------PTFEN 1164 + L + P +P V L+ + + R P F + Sbjct 230 EVESLQDYKSTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289 Query 1165 LIPILKTV 1172 L +K + Sbjct 290 LDSQIKKM 297 Score = 165 bits (417), Expect = 6e-44, Method: Composition-based stats. Identities = 42/267 (16%), Positives = 94/267 (35%), Gaps = 41/267 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ T++ +G+GT VY+GR + G V +K + Sbjct 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQ------------------------VVAMKKIR 36 Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702 + + SL+ ++ H ++ + V ++ ++ E++ L +L Sbjct 37 LESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95 Query 703 RGHV-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 G + Q+ + + ++ ++H ++ +N+L+ G IKL+D G Sbjct 96 PGQFMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKG-------TIKLADFG 148 Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + V + + +PE L G+ ST +D W G E+ Sbjct 149 LARAFGIPIRVYTHEVVTLWYRSPEVLL-GSARYSTPVDIWSIGTIFAELATKKPLFHGD 207 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ P++ +L Sbjct 208 SEIDQLFRIFRALGTPNNEVWPEVESL 234 >sp|Q86CS2|ATG1_DICDI Serine/threonine-protein kinase atg1 OS=Dictyostelium discoideum OX=44689 GN=atg1 PE=3 SV=1 Length=668 Score = 217 bits (552), Expect = 3e-58, Method: Composition-based stats. Identities = 64/269 (24%), Positives = 113/269 (42%), Gaps = 33/269 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK----ADCGPQHRSGWKQEIDILRTLYHE 957 +G G F +V Y + T E A+K + AD + EI IL+ L H Sbjct 12 RIGWGAFAQV----YKGFSIKTNEPFAIKVVDVCRLADKNSKLTENLNYEIRILKELSHT 67 Query 958 HIIKYKGCC-EDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLH 1015 +I++ E+ + ++ME G Y+ H + + L F +Q+ G+ +L Sbjct 68 NIVRLYDVLNEETDPTFIYMIMECCEGGDFSKYIRTHKKLTEEKALYFMKQLANGLKFLR 127 Query 1016 AQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 + +HRDL +N+LL +D +KIGDFG AK + + + + + APE Sbjct 128 QKQIVHRDLKPQNLLLSDDSEHPILKIGDFGFAKFIDP----FSLSDTFCGSPLYMAPEI 183 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 L + +D+WS G+ LYE+L A +V L L + + Sbjct 184 LHRKNYTVKADLWSVGIILYEMLVGEP---------------AYNSGSVPDLLNQL-QNK 227 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 ++ P + +L+ + + + R + Sbjct 228 KIKLPSHISSDCQNLIYSLLQIDVEKRIS 256 Score = 171 bits (434), Expect = 4e-43, Method: Composition-based stats. Identities = 48/286 (17%), Positives = 94/286 (33%), Gaps = 32/286 (11%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + +G G VY+G + V + L Sbjct 6 DYILDKRIGWGAFAQVYKGFSIKTNEPFAIK-------------------VVDVCRLADK 46 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE---NIMVTEYVEHGPLDVWLRRERG 704 + + ++ ++SHT++ ++ V + M+ E E G ++R + Sbjct 47 NSKLTENLNYEIRILKELSHTNIVRLYDVLNEETDPTFIYMIMECCEGGDFSKYIRTHK- 105 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + +QLA+ L +L K +VH ++ +N+LL+ + P +K+ D G Sbjct 106 KLTEEKALYFMKQLANGLKFLRQKQIVHRDLKPQNLLLS----DDSEHPILKIGDFGFAK 161 Query 765 GALS---REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + ++APE L + + D W G L E+ A P Sbjct 162 FIDPFSLSDTFCGSPLYMAPEILH--RKNYTVKADLWSVGIILYEMLVGEPAYNSGSVPD 219 Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 ++ +LP L L + +R S+ Sbjct 220 LLNQLQNKKIKLPSHISSDCQNLIYSLLQIDVEKRISWEDFFNHKW 265 >sp|P51955|NEK2_HUMAN Serine/threonine-protein kinase Nek2 OS=Homo sapiens OX=9606 GN=NEK2 PE=1 SV=1 Length=445 Score = 211 bits (537), Expect = 3e-58, Method: Composition-based stats. Identities = 60/289 (21%), Positives = 108/289 (37%), Gaps = 33/289 (11%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEI 948 + + +G G +G+ C G+++ K L + E+ Sbjct 1 MPSRAEDYEVLYTIGTGSYGR----CQKIRRKSDGKILVWKELDYGSMTEAEKQMLVSEV 56 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-----PRHSIGLAQLLLF 1003 ++LR L H +I++Y D+ +L +VMEY G L + R + +L Sbjct 57 NLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRV 116 Query 1004 AQQICEGMAYLHA-----QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 Q+ + H +HRDL NV LD + VK+GDFGLA+ + + + Sbjct 117 MTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARILNHDTSFAKT- 175 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 ++ +PE + + SD+WS G LYEL + Sbjct 176 --FVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTA--------------- 218 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + L + G+ P + E+ ++ + RP+ E ++ Sbjct 219 FSQKELAGKIREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILE 267 Score = 148 bits (374), Expect = 8e-37, Method: Composition-based stats. Identities = 52/294 (18%), Positives = 97/294 (33%), Gaps = 52/294 (18%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 ++ L +G G+ + R + +G K LD Sbjct 6 EDYEVLYTIGTGSYGRCQKIRRKSDGKILVW------------------------KELDY 41 Query 647 SHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEHGPLDVWLRR- 701 A +L+ ++ H ++ + + +V EY E G L + + Sbjct 42 GSMTEAEKQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKG 101 Query 702 --ERGHVPMAWKMVVAQQLASALSYLENKN-----LVHGNVCGRNILLARLGLAEGTSPF 754 ER ++ + + V QL AL ++ ++H ++ N+ L Sbjct 102 TKERQYLDEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQ-------N 154 Query 755 IKLSDPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 +KL D G+ + V +++PE S + D W G L E+C Sbjct 155 VKLGDFGLARILNHDTSFAKTFVGTPYYMSPE--QMNRMSYNEKSDIWSLGCLLYELCAL 212 Query 811 GEAPLQSRSPSEKEHFYQRQH--RLPEPSCPQLATLTSQCLTYEPTQRPSFRTI 862 P + S E + R+P +L + ++ L + RPS I Sbjct 213 -MPPFTAFSQKELAGKIREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEI 265 >sp|Q4P5N0|STE20_USTMA Serine/threonine-protein kinase SMU1 OS=Ustilago maydis (strain 521 / FGSC 9021) OX=237631 GN=SMU1 PE=3 SV=1 Length=746 Score = 218 bits (556), Expect = 3e-58, Method: Composition-based stats. Identities = 59/262 (23%), Positives = 108/262 (41%), Gaps = 23/262 (9%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 + +G+G G V + GT VA+K + + P+ + EI +++ H +I+ Sbjct 476 QKIGQGASGGV----FTAYQVGTNVSVAIKQMNLEQQPK-KDLIINEILVMKESRHRNIV 530 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + +G+ L +VMEY+ GSL D + + + Q+ ++++ EG+ +LH I Sbjct 531 NFIDSFLFKGD--LWVVMEYMEGGSLTDVVTCNIMTEGQIAAVSREVLEGLRHLHQHGVI 588 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ + NVLL +K+ DFG + E R +W APE + ++ Sbjct 589 HRDIKSDNVLLSLQGDIKLTDFGFCAQIGESQA---KRTTMVGTPYWMAPEVVTRKEYGP 645 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 D+WS G+ E++ PP + T ++ P+ Sbjct 646 KVDIWSLGIMCIEMV-----EGEPPYLNENPLRALYLIATNGT--------PKINNPENL 692 Query 1141 PCEVYHLMKNCWETEASFRPTF 1162 + + +A RP Sbjct 693 SNTFKDFLTTSLDVDAERRPDA 714 Score = 175 bits (443), Expect = 7e-44, Method: Composition-based stats. Identities = 56/314 (18%), Positives = 100/314 (32%), Gaps = 48/314 (15%) Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 +P+ ET I + S L + K L +GQG V+ Sbjct 439 VPRRRETKKSTI----KDSEVIAKLQAICTDADPTKLYRSLQKIGQGASGGVF------- 487 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLA 671 G + V +K ++ +M + H ++ Sbjct 488 -----------------TAYQVGTNVSVAIKQMNLEQQPKKDLIINEILVMKESRHRNIV 530 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 + + +V EY+E G L + + V++++ L +L ++ Sbjct 531 NFIDSFLFKGDLWVVMEYMEGGSLTDVVTCN--IMTEGQIAAVSREVLEGLRHLHQHGVI 588 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGV----GLGALSREERVERIPWLAPECLPGG 787 H ++ N+LL+ G IKL+D G G R V W+APE + Sbjct 589 HRDIKSDNVLLSLQGD-------IKLTDFGFCAQIGESQAKRTTMVGTPYWMAPEVVT-- 639 Query 788 ANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRL----PEPSCPQLAT 843 +D W G +E+ +GE P + +P + PE Sbjct 640 RKEYGPKVDIWSLGIMCIEMV-EGEPPYLNENPLRALYLIATNGTPKINNPENLSNTFKD 698 Query 844 LTSQCLTYEPTQRP 857 + L + +RP Sbjct 699 FLTTSLDVDAERRP 712 >sp|Q9Y572|RIPK3_HUMAN Receptor-interacting serine/threonine-protein kinase 3 OS=Homo sapiens OX=9606 GN=RIPK3 PE=1 SV=2 Length=518 Score = 213 bits (542), Expect = 3e-58, Method: Composition-based stats. Identities = 75/292 (26%), Positives = 124/292 (42%), Gaps = 26/292 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G+G FG V + + G VAVK + + +E+ + +L +E +++ Sbjct 27 VGKGGFGTV----FRAQHRKWGYDVAVKIVNS-------KAISREVKAMASLDNEFVLRL 75 Query 963 KGCCED---QGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQH 1018 +G E + LV +++ GSL L L +++ GM YLH Q+ Sbjct 76 EGVIEKVNWDQDPKPALVTKFMENGSLSGLLQSQCPRPWPLLCRLLKEVVLGMFYLHDQN 135 Query 1019 --YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL--K 1074 +HRDL NVLLD + VK+ DFGL+ E G + + APE Sbjct 136 PVLLHRDLKPSNVLLDPELHVKLADFGLSTFQGGSQSGTGSGEPG-GTLGYLAPELFVNV 194 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 K ASDV+SFG+ ++ +L + PT+ + + L EL + G Sbjct 195 NRKASTASDVYSFGILMWAVLAGREV--ELPTEPSLVYEAVCNRQNRPSLAELPQAGPET 252 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSV 1186 P + + LM+ CW +E RP+F+ +P V + + + S Sbjct 253 PGLEG----LKELMQLCWSSEPKDRPSFQECLPKTDEVFQMVENNMNAAVST 300 Score = 179 bits (453), Expect = 2e-46, Method: Composition-based stats. Identities = 67/367 (18%), Positives = 123/367 (34%), Gaps = 66/367 (18%) Query 564 MRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDD 623 M + P +S ++ +E+ G+G V+ + R G Sbjct 1 MSCVKLWPSGAPAPLVSIEELENQELV-----GKGGFGTVFRAQHRKWGYD--------- 46 Query 624 EDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVR---- 679 V +K+++ A M+ + + + + GV + Sbjct 47 ---------------VAVKIVNS------KAISREVKAMASLDNEFVLRLEGVIEKVNWD 85 Query 680 -GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKN--LVHGNVC 736 P+ +VT+++E+G L L+ + P + +++ + YL ++N L+H ++ Sbjct 86 QDPKPALVTKFMENGSLSGLLQSQCPR-PWPLLCRLLKEVVLGMFYLHDQNPVLLHRDLK 144 Query 737 GRNILLARLGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANS 790 N+LL +KL+D G+ E + +LAPE Sbjct 145 PSNVLLD-------PELHVKLADFGLSTFQGGSQSGTGSGEPGGTLGYLAPELFVNVNRK 197 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQ---------- 840 STA D + FG + + E L + E RQ+R PQ Sbjct 198 ASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAVCNRQNRPSLAELPQAGPETPGLEG 257 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 L L C + EP RPSF+ L + ++ + I Sbjct 258 LKELMQLCWSSEPKDRPSFQECLPKTDEVFQMVENNMNAAVSTVKDFLSQLRSSNRRFSI 317 Query 901 RDLGEGH 907 + G+G Sbjct 318 PESGQGG 324 >sp|Q84UI5|MPK1_ORYSJ Mitogen-activated protein kinase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=MPK1 PE=1 SV=1 Length=398 Score = 209 bits (533), Expect = 3e-58, Method: Composition-based stats. Identities = 71/308 (23%), Positives = 113/308 (37%), Gaps = 29/308 (9%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KA 934 + + +Y I +G+G +G V N TGE VA+K + A Sbjct 46 HGGRFIQYNIFGNVFEVTAKYKPPILPIGKGAYGIVC----SALNSETGEQVAIKKIANA 101 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGSLRDYLP 991 +EI +LR + HE+I+ + + + + E + L + Sbjct 102 FDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPPQRNSFNDVYIAYELMD-TDLHQIIR 160 Query 992 -RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 ++ F QI G+ Y+H+ + +HRDL N+LL+ + +KI DFGLA+ E Sbjct 161 SNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARTTSE 220 Query 1051 GHEYYRVREDGDSPVFWYAPE-CLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-----SP 1104 + ++ APE L ++ A DVWS G EL+ Sbjct 221 TD----FMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 276 Query 1105 PTKFLELIGIAQG------QMTVLRLTELLERGERLPRPDKCP---CEVYHLMKNCWETE 1155 +ELIG R L R R P+K P L++ + Sbjct 277 LRLLMELIGTPNEADLDFVNENARRYIRQLPRHARQSFPEKFPHVHPLAIDLVEKMLTFD 336 Query 1156 ASFRPTFE 1163 R T E Sbjct 337 PRQRITVE 344 Score = 130 bits (327), Expect = 5e-31, Method: Composition-based stats. Identities = 34/219 (16%), Positives = 77/219 (35%), Gaps = 22/219 (10%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF--YE 657 NV+E + + P + + +V +K + + + A Sbjct 56 FGNVFEVTAKYKPPILPIGK--GAYGIVCSALNSETGEQVAIKKIANAFDNKIDAKRTLR 113 Query 658 TASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 L+ + H ++ + + + + E ++ L +R + + Sbjct 114 EIKLLRHMDHENIVAIRDIIPPPQRNSFNDVYIAYELMD-TDLHQIIRSNQA-LSEEHCQ 171 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+ L Y+ + N++H ++ N+LL + +K+ D G+ + Sbjct 172 YFLYQILRGLKYIHSANVLHRDLKPSNLLLN-------ANCDLKICDFGLARTTSETDFM 224 Query 771 -ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 E V + APE L ++ + A+D W G +E+ Sbjct 225 TEYVVTRWYRAPELLLN-SSEYTAAIDVWSVGCIFMELM 262 >sp|Q5REX1|SIK2_PONAB Serine/threonine-protein kinase SIK2 OS=Pongo abelii OX=9601 GN=SIK2 PE=2 SV=1 Length=925 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 72/291 (25%), Positives = 111/291 (38%), Gaps = 29/291 (10%) Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADC 936 + + + LG+G+F V L + T VA+K + K+ Sbjct 1 MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLG----RHRITKTEVAIKIIDKSQL 56 Query 937 GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SI 995 + +E+ I++ L H HIIK E + L LV EY G + DYL H + Sbjct 57 DAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKS--MLYLVTEYAKNGEIFDYLANHGRL 114 Query 996 GLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYY 1055 ++ QI + Y H + +HRDL A N+LLDN+ +KI DF G Sbjct 115 NESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFSFGNFFKSGELLA 174 Query 1056 RVREDGDSPVFWYAPECLKEYKF-YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 R + APE + ++ D+WS GV LY L+ P Sbjct 175 TWR----GSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGP---------- 220 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 T+ L + + G R P + HL++ + S R T + Sbjct 221 -----TLPILRQRVLEG-RFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQI 265 Score = 191 bits (485), Expect = 2e-48, Method: Composition-based stats. Identities = 63/323 (20%), Positives = 109/323 (34%), Gaps = 43/323 (13%) Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 PR L + RV +I LG+G V GR R+ Sbjct 7 PRHLQRGPV---RVGFYDIE--GTLGKGNFAVVKLGRHRI-------------------- 41 Query 631 RDRGQELRVVLKVLDPSHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTE 688 + V +K++D S D Y +M + H H+ ++ V +VTE Sbjct 42 ----TKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTE 97 Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 Y ++G + +L G + + Q+ SA+ Y + +VH ++ N+LL Sbjct 98 YAKNGEIFDYLANH-GRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDN---- 152 Query 749 EGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + IK++D G S E P+ APE G +D W G L Sbjct 153 ---NMNIKIADFSFGNFFKSGELLATWRGSPPYAAPEVFEGQQYE-GPQLDIWSMGVVLY 208 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 + P ++ + + R+P L + L +P++R + I Sbjct 209 VLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEH 268 Query 866 LTRLQPHNLADVLTVNPDSPASD 888 L + + + Sbjct 269 KWMLIEVPVQRPVLYPQEQENEP 291 >sp|Q55GC2|DST2_DICDI Serine/threonine-protein kinase dst2 OS=Dictyostelium discoideum OX=44689 GN=dst2 PE=3 SV=1 Length=1142 Score = 223 bits (568), Expect = 4e-58, Method: Composition-based stats. Identities = 68/272 (25%), Positives = 113/272 (42%), Gaps = 30/272 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 ++ EG FG V Y + TG ++AVK + D EIDIL H +I+K Sbjct 25 EIAEGSFGTV----YKGKHLPTGNIMAVKIIALDEDETF-EDLVVEIDILNRCNHNNIVK 79 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIG--LAQLLLFAQQICEGMAYLHAQHY 1019 Y G E L + ME GS+ + +I +Q+ ++ +G+ YLH + Sbjct 80 YYGSWVKGDE--LFIAMECCGGGSITEIYQELNIPLNESQIAYVCRETLKGLEYLHHTNV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY--- 1076 IHRDL N+LL VK+ DFG++ + + + R +W APE ++ Sbjct 138 IHRDLKGANILLTESGDVKLADFGVSGLLDKSSK----RNTFIGTPYWMAPEVIENRSNP 193 Query 1077 -KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + +D+WS G+TL EL + S L I +L Sbjct 194 VPYDTKADIWSLGITLIELA-EAEPPLSEIHPMKVLFQIPY------------RDPPKLK 240 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + + +++C + + + R T L+ Sbjct 241 NQENYSKDFINFIQSCLQKDPNQRKTATELLK 272 Score = 201 bits (510), Expect = 4e-51, Method: Composition-based stats. Identities = 55/301 (18%), Positives = 106/301 (35%), Gaps = 41/301 (14%) Query 576 LSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQ 635 L + + + +G+ VY+G+ G+ Sbjct 7 LEPFVGKEDPVELFELIEEIAEGSFGTVYKGKHLPTGN---------------------- 44 Query 636 ELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPL 695 + +K++ + ++++ +H ++ +G V+G E + E G + Sbjct 45 --IMAVKIIALDEDETFEDLVVEIDILNRCNHNNIVKYYGSWVKGDELFIAMECCGGGSI 102 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 + + + V ++ L YL + N++H ++ G NILL G + Sbjct 103 TEIYQELNIPLNESQIAYVCRETLKGLEYLHHTNVIHRDLKGANILLTESGD-------V 155 Query 756 KLSDPGVG---LGALSREERVERIPWLAPECLPGGAN--SLSTAMDKWGFGATLLEICFD 810 KL+D GV + R + W+APE + +N T D W G TL+E+ + Sbjct 156 KLADFGVSGLLDKSSKRNTFIGTPYWMAPEVIENRSNPVPYDTKADIWSLGITLIELA-E 214 Query 811 GEAPLQSRSPSEKEHFYQRQH----RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 E PL P + + + E CL +P QR + +L+ Sbjct 215 AEPPLSEIHPMKVLFQIPYRDPPKLKNQENYSKDFINFIQSCLQKDPNQRKTATELLKHP 274 Query 867 T 867 Sbjct 275 F 275 >sp|P31751|AKT2_HUMAN RAC-beta serine/threonine-protein kinase OS=Homo sapiens OX=9606 GN=AKT2 PE=1 SV=2 Length=481 Score = 212 bits (539), Expect = 4e-58, Method: Composition-based stats. Identities = 77/390 (20%), Positives = 128/390 (33%), Gaps = 61/390 (16%) Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQC--LTYEPTQRPSFRTILRDLTRL 869 EAP Q+ P +F + +L + P+ T +C T + + + Sbjct 43 EAPDQTLPP--LNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWM 100 Query 870 QPHNLADVLTVNPDSPASDPTVFH------------------------KRYLKKIRDLGE 905 + + ++ LG+ Sbjct 101 RAIQMVANSLKQRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGK 160 Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYK 963 G FGKV L TG A+K L+ + + E +L+ H + K Sbjct 161 GTFGKVILV----REKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALK 216 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHR 1022 Q L VMEY G L +L R + + +I + YLH++ ++R Sbjct 217 YAF--QTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYR 274 Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082 D+ N++LD D +KI DFGL K EG + + APE L++ + A Sbjct 275 DIKLENLMLDKDGHIKITDFGLCK---EGISDGATMKTFCGTPEYLAPEVLEDNDYGRAV 331 Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 D W GV +YE++ Q +L R PR Sbjct 332 DWWGLGVVMYEMMCGRLPF--------------YNQDHERLFELILMEEIRFPR--TLSP 375 Query 1143 EVYHLMKNCWETEASFR----PT-FENLIP 1167 E L+ + + R P+ + ++ Sbjct 376 EAKSLLAGLLKKDPKQRLGGGPSDAKEVME 405 Score = 167 bits (422), Expect = 1e-42, Method: Composition-based stats. Identities = 62/308 (20%), Positives = 110/308 (36%), Gaps = 46/308 (15%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 P ++S M A + R +V + L LG+GT V +R + + Sbjct 126 SPSDSSTTEEMEVAVSKAR---------AKVTMNDFDYLKLLGKGTFGKVI--LVREKAT 174 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 G K+ ++ ++ + + + ++ H L + Sbjct 175 GRYYAMKILRKEVIIAKDEVAHTVT-------------------ESRVLQNTRHPFLTAL 215 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHG 733 V EY G L L RER ++ SAL YL ++++V+ Sbjct 216 KYAFQTHDRLCFVMEYANGGELFFHLSRER-VFTEERARFYGAEIVSALEYLHSRDVVYR 274 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGAN 789 ++ N++L + G IK++D G+ +S + +LAPE L N Sbjct 275 DIKLENLMLDKDG-------HIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLED--N 325 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQC 848 A+D WG G + E+ G P ++ + R P P+ +L + Sbjct 326 DYGRAVDWWGLGVVMYEMMC-GRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGL 384 Query 849 LTYEPTQR 856 L +P QR Sbjct 385 LKKDPKQR 392 >sp|Q9M9E9|SRK2C_ARATH Serine/threonine-protein kinase SRK2C OS=Arabidopsis thaliana OX=3702 GN=SRK2C PE=1 SV=1 Length=343 Score = 207 bits (528), Expect = 4e-58, Method: Composition-based stats. Identities = 82/296 (28%), Positives = 125/296 (42%), Gaps = 34/296 (11%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 + ++D+G G+FG L + + E+ AVK + + G + ++EI R+ Sbjct 1 MERYEIVKDIGSGNFGVAKLV----RDKFSKELFAVKFI--ERGQKIDEHVQREIMNHRS 54 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012 L H +II++K L LVMEY G L + + F QQ+ G+ Sbjct 55 LIHPNIIRFKEVLLTATH--LALVMEYAAGGELFGRICSAGRFSEDEARFFFQQLISGVN 112 Query 1013 YLHAQHYIHRDLAARNVLLD--NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 Y H+ HRDL N LLD VKI DFG +K G + + + +P + AP Sbjct 113 YCHSLQICHRDLKLENTLLDGSEAPRVKICDFGYSK---SGVLHSQPKTTVGTPA-YIAP 168 Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSP--PTKFLELIGIAQGQMTVLRLTEL 1127 E L ++ +DVWS GVTLY +L + P P F + IG + Sbjct 169 EVLSTKEYDGKIADVWSCGVTLYVMLVGAYPFEDPSDPKDFRKTIG------------RI 216 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP---ILKTV-HEKYQGQ 1179 L+ +P + E HL+ + R T E + LK + E Y+G Sbjct 217 LKAQYAIPDYVRVSDECRHLLSRIFVANPEKRITIEEIKNHSWFLKNLPVEMYEGS 272 Score = 145 bits (365), Expect = 1e-36, Method: Composition-based stats. Identities = 47/275 (17%), Positives = 85/275 (31%), Gaps = 17/275 (6%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 RD+ + +K ++ I + H ++ V + +V EY Sbjct 22 RDKFSKELFAVKFIERG-QKIDEHVQREIMNHRSLIHPNIIRFKEVLLTATHLALVMEYA 80 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L + G QQL S ++Y + + H ++ N LL Sbjct 81 AGGELFGRI-CSAGRFSEDEARFFFQQLISGVNYCHSLQICHRDLKLENTLLD-----GS 134 Query 751 TSPFIKLSDPGVGLGAL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +P +K+ D G + + V ++APE L D W G TL + Sbjct 135 EAPRVKICDFGYSKSGVLHSQPKTTVGTPAYIAPEVLSTKEYD-GKIADVWSCGVTLYVM 193 Query 808 CFDGEAPLQSRSPSEKEH----FYQRQHRLPEP--SCPQLATLTSQCLTYEPTQRPSFRT 861 P + + Q+ +P+ + L S+ P +R + Sbjct 194 LVGAYPFEDPSDPKDFRKTIGRILKAQYAIPDYVRVSDECRHLLSRIFVANPEKRITIEE 253 Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRY 896 I L+ + + S TV + Sbjct 254 IKNHSWFLKNLPVEMYEGSLMMNGPSTQTVEEIVW 288 >sp|Q9LT35|NEK6_ARATH Serine/threonine-protein kinase Nek6 OS=Arabidopsis thaliana OX=3702 GN=NEK6 PE=3 SV=1 Length=416 Score = 210 bits (534), Expect = 4e-58, Method: Composition-based stats. Identities = 62/285 (22%), Positives = 112/285 (39%), Gaps = 31/285 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG L + VK ++ A + + QE+ ++ L +I++ Sbjct 10 IGRGAFGSAFLVIHKSERR----KYVVKKIRLAKQTERCKLAAIQEMSLISKLKSPYIVE 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018 YK ++ + +V Y G + + + +L + Q+ + YLH Sbjct 66 YKDSWVEKD--CVCIVTSYCEGGDMTQMIKKSRGVFASEEKLCRWMVQLLLAIDYLHNNR 123 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRDL N+ L + V++GDFGLAK + + + + PE L + + Sbjct 124 VLHRDLKCSNIFLTKENEVRLGDFGLAKLLGKDD----LASSMVGTPNYMCPELLADIPY 179 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 Y SD+WS G ++E+ H + ++P + L + R P P Sbjct 180 GYKSDIWSLGCCMFEVAAHQPAFKAP---------------DMAALINKINRSSLSPLPV 224 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAP 1181 + L+K+ RPT L+ P L+ + Q +P Sbjct 225 MYSSSLKRLIKSMLRKNPEHRPTAAELLRHPHLQPYLAQCQNLSP 269 Score = 150 bits (378), Expect = 2e-37, Method: Composition-based stats. Identities = 51/297 (17%), Positives = 89/297 (30%), Gaps = 36/297 (12%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + + +G+G + + LV + ++ V L Sbjct 1 MDDYEVVEQIGRGAFGSAF----------------------LVIHKSERRKYVVKKIRLA 38 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 LA + SL+S++ ++ V +VT Y E G + +++ RG Sbjct 39 KQTERCKLAAIQEMSLISKLKSPYIVEYKDSWVEKDCVCIVTSYCEGGDMTQMIKKSRGV 98 Query 706 V-PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 QL A+ YL N ++H ++ NI L + ++L D G+ Sbjct 99 FASEEKLCRWMVQLLLAIDYLHNNRVLHRDLKCSNIFLTKENE-------VRLGDFGLAK 151 Query 765 GALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + V ++ PE L D W G + E+ A + Sbjct 152 LLGKDDLASSMVGTPNYMCPELLADIPYGY--KSDIWSLGCCMFEVAAHQPAFKAPDMAA 209 Query 822 EKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 + LP L L L P RP+ +LR Sbjct 210 LINKINRSSLSPLPVMYSSSLKRLIKSMLRKNPEHRPTAAELLRHPHLQPYLAQCQN 266 >sp|Q41639|CDC2_VIGAC Cell division control protein 2 homolog OS=Vigna aconitifolia OX=3918 GN=CDC2 PE=2 SV=1 Length=294 Score = 206 bits (523), Expect = 4e-58, Method: Composition-based stats. Identities = 71/293 (24%), Positives = 121/293 (41%), Gaps = 29/293 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ Sbjct 1 MEQYEKVEKIGEGTYGVV----YKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009 + H +I++ + EK L LV EY+ L L+ ++ P Q+ +F QI Sbjct 57 EMQHRNIVRLQDVV--HSEKRLYLVFEYLDL-DLKKHMDSSPEFVKDPRQVKMFLYQILC 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 G+AY H+ +HRDL +N+L+D +K+ DFGLA+A R +++ Sbjct 114 GIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIP---VRTFTHEVVTLWYR 170 Query 1069 APECLKEYK-FYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVL 1122 APE L + + DVWS G E++ DS K ++G + Sbjct 171 APEILLGSRHYSTPVDVWSVGCIFAEMVNRRPLFPGDSEIDELFKIFRILGTPNEETWPG 230 Query 1123 RLTELLERGERLPRPDKCPCEV--------YHLMKNCWETEASFRPTFENLIP 1167 + P K V +L+ + + S R T + Sbjct 231 VTALPDFKSTFPKWPPKDLATVVPNLDAAGLNLLSSMLCLDPSKRITARIAVE 283 Score = 164 bits (414), Expect = 2e-43, Method: Composition-based stats. Identities = 46/266 (17%), Positives = 94/266 (35%), Gaps = 39/266 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 ++ ++ +G+GT VY+ RDR + LK Sbjct 1 MEQYEKVEKIGEGTYGVVYKA------------------------RDRVTNETIALKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 L+ + SL+ ++ H ++ + V +V EY++ L + Sbjct 37 LEQEDEGVPSTAIREISLLKEMQHRNIVRLQDVVHSEKRLYLVFEYLDL-DLKKHMDSSP 95 Query 704 GHVPMAWKMVV-AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 V ++ + Q+ ++Y + ++H ++ +N+L+ R + +KL+D G+ Sbjct 96 EFVKDPRQVKMFLYQILCGIAYCHSHRVLHRDLKPQNLLIDRR------TNSLKLADFGL 149 Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + + APE L G+ ST +D W G E+ Sbjct 150 ARAFGIPVRTFTHEVVTLWYRAPEILL-GSRHYSTPVDVWSVGCIFAEMVNRRPLFPGDS 208 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844 E ++ E + P + L Sbjct 209 EIDELFKIFRILGTPNEETWPGVTAL 234 >sp|P22612|KAPCG_HUMAN cAMP-dependent protein kinase catalytic subunit gamma OS=Homo sapiens OX=9606 GN=PRKACG PE=1 SV=3 Length=351 Score = 207 bits (528), Expect = 4e-58, Method: Composition-based stats. Identities = 67/261 (26%), Positives = 108/261 (41%), Gaps = 31/261 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHI 959 LG G FG+V L + TG A+K L + E IL+ + + Sbjct 49 TLGMGSFGRVMLV----RHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFL 104 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQH 1018 +K + +D L LVMEYVP G + L R +A Q+ + YLH+ Sbjct 105 VKLQFSFKDNS--YLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLD 162 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRDL N+L+D +++ DFG AK V R +P + APE + + Sbjct 163 LIHRDLKPENLLIDQQGYLQVTDFGFAKRVK-----GRTWTLCGTPE-YLAPEIILSKGY 216 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 A D W+ GV +YE+ + +++ E + G R+ P Sbjct 217 NKAVDWWALGVLIYEMAVGFPPFYAD---------------QPIQIYEKIVSG-RVRFPS 260 Query 1139 KCPCEVYHLMKNCWETEASFR 1159 K ++ HL+++ + + + R Sbjct 261 KLSSDLKHLLRSLLQVDLTKR 281 Score = 155 bits (391), Expect = 7e-40, Method: Composition-based stats. Identities = 52/325 (16%), Positives = 101/325 (31%), Gaps = 34/325 (10%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + + +L LG G+ V R + G + ++ V + Sbjct 37 NTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKIL-------------NKQKVVKM 83 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 K ++ ++ + L + +V EYV G + L+R Sbjct 84 KQVEH--------ILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQR 135 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 G A Q+ A+ YL + +L+H ++ N+L+ + G +++++D G Sbjct 136 V-GRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQG-------YLQVTDFG 187 Query 762 VGLGALSRE-ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 R +LAPE + + + A+D W G + E+ G P + P Sbjct 188 FAKRVKGRTWTLCGTPEYLAPEIIL--SKGYNKAVDWWALGVLIYEMAV-GFPPFYADQP 244 Query 821 SEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 + E + R P L L L + T+R + Sbjct 245 IQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWI 304 Query 880 VNPDSPASDPTVFHKRYLKKIRDLG 904 + P + + Sbjct 305 AIYEKKVEAPFIPKYTGPGDASNFD 329 >sp|Q9C6P3|CDPKX_ARATH Calcium-dependent protein kinase 33 OS=Arabidopsis thaliana OX=3702 GN=CPK33 PE=1 SV=1 Length=521 Score = 213 bits (542), Expect = 4e-58, Method: Composition-based stats. Identities = 76/287 (26%), Positives = 119/287 (41%), Gaps = 30/287 (10%) Query 888 DPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWK 945 P K + ++LG G FG L T TG+ A K++ K + + Sbjct 64 KPYEDVKLFYTLSKELGRGQFGVTYLC----TEKSTGKRFACKSISKKKLVTKGDKEDMR 119 Query 946 QEIDILRTLYH-EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLF 1003 +EI I++ L +I+++KG ED EK++ LVME G L D L + Sbjct 120 REIQIMQHLSGQPNIVEFKGAYED--EKAVNLVMELCAGGELFDRILAKGHYSERAAASV 177 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 +QI + H +HRDL N LL D L+K DFGL+ + EG RV +D Sbjct 178 CRQIVNVVNICHFMGVMHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEG----RVYKD 233 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 ++ APE LK ++ D+WS G+ LY LL+ + K + I +G++ Sbjct 234 IVGSAYYVAPEVLK-RRYGKEIDIWSAGIILYILLSGVPPFWAETEKGI-FDAILEGEID 291 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 E P P L++ + R + ++ Sbjct 292 F----------ESQPWP-SISNSAKDLVRRMLTQDPKRRISAAEVLK 327 Score = 134 bits (336), Expect = 2e-31, Method: Composition-based stats. Identities = 48/287 (17%), Positives = 87/287 (30%), Gaps = 39/287 (14%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 T LG+G Y + +G K + LV D+ Sbjct 74 TLSKELGRGQFGVTY--LCTEKSTGKRFACKSISKKKLVTKGDK---------------- 115 Query 650 DIALAFYETASLMSQVS-HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM 708 +M +S ++ G +V E G L + +GH Sbjct 116 ---EDMRREIQIMQHLSGQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRILA-KGHYSE 171 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 V +Q+ + ++ ++H ++ N LL+ + IK +D G+ + Sbjct 172 RAAASVCRQIVNVVNICHFMGVMHRDLKPENFLLSS----KDEKALIKATDFGLSVFIEE 227 Query 769 R---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 ++ V ++APE L +D W G L I G P + + Sbjct 228 GRVYKDIVGSAYYVAPEVL---KRRYGKEIDIWSAGIILY-ILLSGVPPFWAETEKGIFD 283 Query 826 FYQRQH-----RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + L + LT +P +R S +L+ Sbjct 284 AILEGEIDFESQPWPSISNSAKDLVRRMLTQDPKRRISAAEVLKHPW 330 >sp|Q9W739|CDK1_RANDY Cyclin-dependent kinase 1 OS=Rana dybowskii OX=71582 GN=CDK1 PE=2 SV=1 Length=302 Score = 206 bits (523), Expect = 4e-58, Method: Composition-based stats. Identities = 68/295 (23%), Positives = 124/295 (42%), Gaps = 33/295 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHII 960 +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ L H +I+ Sbjct 9 KIGEGTYGVV----YKGVHKATGQIVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIV 64 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQICEGMAYLHA 1016 + L L+ E++ + L+ YL + + + QI +G+ + HA Sbjct 65 CLLDVLMQ--DSRLYLIFEFLSM-DLKKYLDSIPSGQYLEAMLVKSYLYQILQGIIFCHA 121 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + +HRDL +N+L+D+ ++K+ DFGLA+A RV +++ APE L Sbjct 122 RRVLHRDLKPQNLLIDSKGVIKLADFGLARAFGIP---VRVYTHEVVTLWYRAPEVLLGS 178 Query 1077 -KFYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 ++ DVWS G E+ + H DS + EL G ++ + L + Sbjct 179 VRYSTPVDVWSIGTIFAEIASKKPLFHGDSEIDQLFRISELWGTPNNEV-WPEVESLQDY 237 Query 1131 GERLPR---------PDKCPCEVYHLMKNCWETEASFRPTFEN--LIPILKTVHE 1174 P+ E L+ + + R + L P + + Sbjct 238 KNTFPKWKGGSLAANVKNIDKEGLDLLAKMLVYDPAKRISARKALLHPYFDDLDK 292 Score = 161 bits (408), Expect = 1e-42, Method: Composition-based stats. Identities = 45/267 (17%), Positives = 91/267 (34%), Gaps = 41/267 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 E ++ +G+GT VY+G + G V +K Sbjct 1 MDEYAKIEKIGEGTYGVVYKGVHKATGQ------------------------IVAMKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702 L+ + SL+ ++ H ++ + V ++ ++ E++ L +L Sbjct 37 LENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95 Query 703 RGHVPMAWKMV-VAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 G A + Q+ + + + ++H ++ +N+L+ G+ IKL+D G Sbjct 96 SGQYLEAMLVKSYLYQILQGIIFCHARRVLHRDLKPQNLLIDSKGV-------IKLADFG 148 Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + V + + APE L G+ ST +D W G EI Sbjct 149 LARAFGIPVRVYTHEVVTLWYRAPEVLL-GSVRYSTPVDVWSIGTIFAEIASKKPLFHGD 207 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844 + + P++ +L Sbjct 208 SEIDQLFRISELWGTPNNEVWPEVESL 234 >sp|C0LGX3|HSL2_ARATH LRR receptor-like serine/threonine-protein kinase HSL2 OS=Arabidopsis thaliana OX=3702 GN=HSL2 PE=1 SV=1 Length=993 Score = 221 bits (564), Expect = 4e-58, Method: Composition-based stats. Identities = 76/345 (22%), Positives = 128/345 (37%), Gaps = 42/345 (12%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 + L + L + +G G G V Sbjct 651 LFIKTKPLFKRKPKRTNKITIFQRVGFTEEDIYPQLTEDNIIGSGGSGLVYRVKLK---- 706 Query 922 GTGEMVAVKALKADCGPQHRSG--WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVME 979 +G+ +AVK L + G + S ++ E++ L + H +I+K CC GE+ LV E Sbjct 707 -SGQTLAVKKLWGETGQKTESESVFRSEVETLGRVRHGNIVKLLMCC--NGEEFRFLVYE 763 Query 980 YVPLGSLRDYLPRHS-------IGLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNV 1029 ++ GSL D L + A +G++YLH +HRD+ + N+ Sbjct 764 FMENGSLGDVLHSEKEHRAVSPLDWTTRFSIAVGAAQGLSYLHHDSVPPIVHRDVKSNNI 823 Query 1030 LLDNDRLVKIGDFGLAKAVPEGHE---YYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 LLD++ ++ DFGLAK + + APE K SDV+S Sbjct 824 LLDHEMKPRVADFGLAKPLKREDNDGVSDVSMSCVAGSYGYIAPEYGYTSKVNEKSDVYS 883 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQM-------------------TVLRLTEL 1127 FGV L EL+T + S + +++ A L++L Sbjct 884 FGVVLLELITGKRPNDSSFGENKDIVKFAMEAALCYPSPSAEDGAMNQDSLGNYRDLSKL 943 Query 1128 LERGERL-PRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKT 1171 ++ +L R + +V + C + RPT ++ +LK Sbjct 944 VDPKMKLSTREYEEIEKVLDVALLCTSSFPINRPTMRKVVELLKE 988 Score = 184 bits (467), Expect = 4e-46, Method: Composition-based stats. Identities = 51/277 (18%), Positives = 92/277 (33%), Gaps = 56/277 (20%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 ++T+ + +G G VY +L+ + +K L Sbjct 685 QLTEDNIIGSGGSGLVYRVKLKSGQTL-------------------------AVKKLWGE 719 Query 648 HHDIALA---FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + F + +V H ++ + C +V E++E+G L L E+ Sbjct 720 TGQKTESESVFRSEVETLGRVRHGNIVKLLMCCNGEEFRFLVYEFMENGSLGDVLHSEKE 779 Query 705 H-----VPMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIK 756 H + + +A A LSYL + + +VH +V NILL + Sbjct 780 HRAVSPLDWTTRFSIAVGAAQGLSYLHHDSVPPIVHRDVKSNNILLDHEMKP-------R 832 Query 757 LSDPGVGL----------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 ++D G+ +S ++APE G + ++ D + FG LLE Sbjct 833 VADFGLAKPLKREDNDGVSDVSMSCVAGSYGYIAPEY--GYTSKVNEKSDVYSFGVVLLE 890 Query 807 ICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLAT 843 + G+ P S K+ P Sbjct 891 LI-TGKRPNDSSFGENKDIVKFAMEAALCYPSPSAED 926 >sp|Q75LR7|SAPK1_ORYSJ Serine/threonine-protein kinase SAPK1 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK1 PE=1 SV=1 Length=342 Score = 207 bits (527), Expect = 4e-58, Method: Composition-based stats. Identities = 70/276 (25%), Positives = 113/276 (41%), Gaps = 26/276 (9%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 + +RD+G G+FG L + T + AVK + + G + ++EI R+ Sbjct 1 MERYEVMRDIGSGNFGVAKLV----RDVATNHLFAVKFI--ERGLKIDEHVQREIMNHRS 54 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMA 1012 L H +II++K L +VMEY G L + + + F QQ+ G++ Sbjct 55 LKHPNIIRFKEVVLTPTH--LAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVS 112 Query 1013 YLHAQHYIHRDLAARNVLLDNDRL--VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 Y H+ HRDL N LLD +KI DFG +K + + + +P + AP Sbjct 113 YCHSMQVCHRDLKLENTLLDGSVTPRLKICDFGYSK---SSVLHSQPKSTVGTPA-YIAP 168 Query 1071 ECLKEYKFYYAS-DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E L ++ DVWS GVTLY +L + P + +T +L Sbjct 169 EVLSRKEYDGKVADVWSCGVTLYVMLVGAYPFEDPDD----------PRNFRKTITRILS 218 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 +P + + HL+ + R T + Sbjct 219 VQYSIPDYVRVSADCRHLLSRIFVGNPEQRITIPEI 254 Score = 150 bits (379), Expect = 2e-38, Method: Composition-based stats. Identities = 51/348 (15%), Positives = 96/348 (28%), Gaps = 45/348 (13%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + + +G G RD +K ++ Sbjct 1 MERYEVMRDIGSGNFG------------------------VAKLVRDVATNHLFAVKFIE 36 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 I + H ++ V + +V EY G L + G Sbjct 37 RG-LKIDEHVQREIMNHRSLKHPNIIRFKEVVLTPTHLAIVMEYAAGGELFERI-CNAGR 94 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 QQL S +SY + + H ++ N LL +P +K+ D G Sbjct 95 FSEDEARFFFQQLISGVSYCHSMQVCHRDLKLENTLLD-----GSVTPRLKICDFGYSKS 149 Query 766 AL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 ++ + V ++APE L D W G TL + G P + P + Sbjct 150 SVLHSQPKSTVGTPAYIAPEVLSRKEYD-GKVADVWSCGVTLYVMLV-GAYPFED--PDD 205 Query 823 KEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880 +F + R+ + S P +++ C + ++ H Sbjct 206 PRNFRKTITRILSVQYSIPDYVRVSADCRHLLSRIFVGNPEQRITIPEIKNHPWFLKNLP 265 Query 881 NPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 + ++ + L +V + G +A Sbjct 266 IEMTDEYQRSMQLADMNTPSQSLE-----EVMAIIQEARKPGDAMKLA 308 >sp|Q7XKA8|SAPK5_ORYSJ Serine/threonine-protein kinase SAPK5 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK5 PE=2 SV=1 Length=370 Score = 208 bits (529), Expect = 5e-58, Method: Composition-based stats. Identities = 75/298 (25%), Positives = 124/298 (42%), Gaps = 29/298 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 + +R++G G+FG L N T E+VA+K + + G + +EI R+ Sbjct 1 MEKYEPVREIGAGNFGVAKLM----RNKETRELVAMKFI--ERGNRIDENVFREIVNHRS 54 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMA 1012 L H +II++K + L +VMEY G L + + + F QQ+ G++ Sbjct 55 LRHPNIIRFKEVVVTG--RHLAIVMEYAAGGELFERICEAGRFHEDEARYFFQQLVCGVS 112 Query 1013 YLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 Y HA HRDL N LLD +KI DFG +K + R + +P + AP Sbjct 113 YCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSK---SSLLHSRPKSTVGTPA-YIAP 168 Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E L ++ +DVWS GVTLY +L + P I++ ++ E + Sbjct 169 EVLSRREYDGKLADVWSCGVTLYVMLVGAYPFEDPKDPKNFRKTISRIMSVQYKIPEYV- 227 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP---ILKTVHEKYQGQAPSVF 1184 HL+ + R + + LK + + + +A +V+ Sbjct 228 ---------HVSQPCRHLLSRIFVANPYKRISMGEIKSHPWFLKNLPRELKEEAQAVY 276 Score = 153 bits (386), Expect = 4e-39, Method: Composition-based stats. Identities = 52/295 (18%), Positives = 86/295 (29%), Gaps = 41/295 (14%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ + +G G R++ V +K ++ Sbjct 1 MEKYEPVREIGAGNFG------------------------VAKLMRNKETRELVAMKFIE 36 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 + F + H ++ V V G +V EY G L + E G Sbjct 37 RGNRIDENVF-REIVNHRSLRHPNIIRFKEVVVTGRHLAIVMEYAAGGELFERI-CEAGR 94 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 QQL +SY + H ++ N LL +P +K+ D G Sbjct 95 FHEDEARYFFQQLVCGVSYCHAMQICHRDLKLENTLLD-----GSPAPRLKICDFGYSKS 149 Query 766 ALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 +L + V ++APE L D W G TL + + P Sbjct 150 SLLHSRPKSTVGTPAYIAPEVLSRREYD-GKLADVWSCGVTLYVMLVGAYPFEDPKDPKN 208 Query 823 ----KEHFYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 Q+++PE L S+ P +R S I L+ Sbjct 209 FRKTISRIMSVQYKIPEYVHVSQPCRHLLSRIFVANPYKRISMGEIKSHPWFLKN 263 >sp|Q8MYF1|Y2070_DICDI Probable serine/threonine-protein kinase DDB_G0277449 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0277449 PE=3 SV=1 Length=456 Score = 211 bits (537), Expect = 5e-58, Method: Composition-based stats. Identities = 58/267 (22%), Positives = 103/267 (39%), Gaps = 28/267 (10%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRT 953 +G+G FGKV + + T ++ A+K +K + + E DIL+ Sbjct 127 NFIIKHLVGKGGFGKV----FQVVHVDTQKVYALKVIKKNHIIAKKSVVNTLAEKDILKK 182 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMA 1012 + H I+ Q EK L LVM++V G L +L + + Q+ + ++ + Sbjct 183 ISHPFIVNLHYAF--QNEKKLYLVMDFVNGGQLFYHLQKEAIFSEDQVRFYMAELILALE 240 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 +LH + +HRDL N+LLD+ + DFGLAK + + + APE Sbjct 241 HLHDSNIVHRDLKPENILLDSQGHCILTDFGLAKL---EVKTNNETFSFAGTLEYMAPEM 297 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 ++ A D WS G+ +Y+++ + L + E Sbjct 298 IQHATCGKAVDWWSIGILMYDMMIGKPPFEH----------------KNRALMQEKIISE 341 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFR 1159 + P L+ + + R Sbjct 342 KAKFPKFVSSSARSLINGLLTKDPTKR 368 Score = 169 bits (427), Expect = 1e-43, Method: Composition-based stats. Identities = 46/282 (16%), Positives = 95/282 (34%), Gaps = 41/282 (15%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + ++ +G+G V++ + L Sbjct 121 NSINLSNFIIKHLVGKGGFGKVFQVV------------------------HVDTQKVYAL 156 Query 642 KVLDPSH---HDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 KV+ +H + ++ ++SH + +H + +V ++V G L Sbjct 157 KVIKKNHIIAKKSVVNTLAEKDILKKISHPFIVNLHYAFQNEKKLYLVMDFVNGGQLFYH 216 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 L++E +L AL +L + N+VH ++ NILL G L+ Sbjct 217 LQKE-AIFSEDQVRFYMAELILALEHLHDSNIVHRDLKPENILLDSQGHCI-------LT 268 Query 759 DPGVGLGALSREERV----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 D G+ + + ++APE + + A+D W G + ++ Sbjct 269 DFGLAKLEVKTNNETFSFAGTLEYMAPEMIQHA--TCGKAVDWWSIGILMYDMMIGKPPF 326 Query 815 LQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 +E + + P+ +L + LT +PT+R Sbjct 327 EHKNRALMQEKIISEKAKFPKFVSSSARSLINGLLTKDPTKR 368 >sp|Q38HL5|HOG1_ASPGL Mitogen-activated protein kinase hog1 OS=Aspergillus glaucus OX=41413 GN=hog1 PE=3 SV=1 Length=366 Score = 208 bits (529), Expect = 5e-58, Method: Composition-based stats. Identities = 68/283 (24%), Positives = 107/283 (38%), Gaps = 29/283 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + TG VAVK + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVCA----ARDQLTGAPVAVKKIMKPFSTPVLSKRTYRELKLLKHLGHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L L + + F QI G+ Y+H+ Sbjct 80 ICLSDIFISPLED-IYSVTELL-GTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI FGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILINENCDLKICGFGLARVQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------TVLRLTE 1126 D+WS G E+L + + EL+G + LR + Sbjct 192 DVEVDIWSAGCIFAEMLDGKPLFPGKDHVNQFSIITELLGTPPDDVIETICSENTLRFVK 251 Query 1127 LLERGERLP---RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 L + ER P R E L++ + R + Sbjct 252 SLPKRERQPLTSRFKNADPEAVDLLERMLVFDPKKRIRAGEAL 294 Score = 124 bits (312), Expect = 2e-29, Method: Composition-based stats. Identities = 35/231 (15%), Positives = 74/231 (32%), Gaps = 19/231 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E + + M + RD+ V +K ++ P ++ Y Sbjct 10 FGTTFE---ITSRYTELQPVGMGAFGLVCAARDQLTGAPVAVKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L L + + Sbjct 67 ELKLLKHLGHENIICLSDIFISPLEDIYSVTELL-GTDLHRLLTSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ G+ V Sbjct 124 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICGFGLARVQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + APE + +D W G E+ DG+ + + Sbjct 177 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEML-DGKPLFPGKDHVNQFSI 225 >sp|P34102|PK3_DICDI Protein kinase 3 OS=Dictyostelium discoideum OX=44689 GN=pkgC PE=3 SV=2 Length=910 Score = 220 bits (561), Expect = 5e-58, Method: Composition-based stats. Identities = 63/267 (24%), Positives = 110/267 (41%), Gaps = 33/267 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960 LG G FG+V L TG+ A+K L + + E +L T+ H I+ Sbjct 504 LGVGSFGRVYLV----RRKDTGKFYAMKVLNKKDMLKKKQIAHTNTEKMVLSTMDHPFIV 559 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + Q E L + M+YVP G L +L + + ++ + YLH+ + Sbjct 560 RLHFAF--QNEDFLFMCMDYVPGGELFHHLQKAGKFPEELAKFYIAEVICSLHYLHSNNI 617 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKA-------VPEGHEYYRVREDGDSPVFWYAPEC 1072 I+RD+ N+LLD + +K+ DFGL+K+ G E +P + APE Sbjct 618 IYRDIKPENILLDEEGHIKLTDFGLSKSGITSVVGSKNGGEGGFATTFCGTPE-YLAPEI 676 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + A+D WS G+ L+E+LT +A + + + +++ Sbjct 677 ITGAGHGKAADWWSVGILLFEMLTGRSPF------------LASNRNDMYK--SMIQGNL 722 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFR 1159 R+ P + L++ + + R Sbjct 723 RM--PMFLSSDAQDLLEKLLVPDPNKR 747 Score = 174 bits (440), Expect = 5e-43, Method: Composition-based stats. Identities = 57/296 (19%), Positives = 96/296 (32%), Gaps = 50/296 (17%) Query 577 SQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQE 636 ++ S ++ + L LG G+ VY R + G Sbjct 486 NKQSIKKLTIDDFELLKVLGVGSFGRVYLVRRKDTGKFY--------------------- 524 Query 637 LRVVLKVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +KVL+ ++S + H + +H M +YV G Sbjct 525 ---AMKVLNKKDMLKKKQIAHTNTEKMVLSTMDHPFIVRLHFAFQNEDFLFMCMDYVPGG 581 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L L++ G P ++ +L YL + N+++ ++ NILL G Sbjct 582 ELFHHLQKA-GKFPEELAKFYIAEVICSLHYLHSNNIIYRDIKPENILLDEEG------- 633 Query 754 FIKLSDPGVGLGALSR-------------EERVERIPWLAPECLPGGANSLSTAMDKWGF 800 IKL+D G+ ++ +LAPE + G + A D W Sbjct 634 HIKLTDFGLSKSGITSVVGSKNGGEGGFATTFCGTPEYLAPEIITGAGH--GKAADWWSV 691 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 G L E+ L S + Q R+P L + L +P +R Sbjct 692 GILLFEMLTGRSPFLASNRNDMYKSMIQGNLRMPMFLSSDAQDLLEKLLVPDPNKR 747 >sp|Q9UV50|HOG1_DEBHA Mitogen-activated protein kinase HOG1 OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=HOG1 PE=1 SV=3 Length=387 Score = 208 bits (530), Expect = 5e-58, Method: Composition-based stats. Identities = 66/293 (23%), Positives = 109/293 (37%), Gaps = 32/293 (11%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRT 953 + +G G FG V + TG+ VAVK + K +E+ +L+ Sbjct 21 NRYTDLNPVGMGAFGLVC----SAIDKLTGQNVAVKKIMKPFSTSVLAKRTYRELKLLKH 76 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013 L HE++I E + V E L L + + F QI G+ Y Sbjct 77 LRHENLITLDDIFLSPLED-IYFVTEL-QGTDLHRLLTSRPLEKQFIQYFTYQILRGLKY 134 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +H+ IHRDL N+L++ + +KI DFGLA+ Y S ++ APE + Sbjct 135 VHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIM 188 Query 1074 KE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------T 1120 K+ D+WS G L E++ + EL+G + Sbjct 189 LTWQKYDTEVDLWSVGCILSEMIEGKPLFPGKDHVHQFSIITELLGSPPPDVIETICSEN 248 Query 1121 VLRLTELLERGERLPRPD---KCP---CEVYHLMKNCWETEASFRPTFENLIP 1167 LR + L + +P + +C E L+ + R + + + Sbjct 249 TLRFVQSLPHRDPIPFSERFAQCSHVEPEAIDLLAKMLIFDPKKRISALDALS 301 Score = 139 bits (349), Expect = 4e-34, Method: Composition-based stats. Identities = 49/319 (15%), Positives = 91/319 (29%), Gaps = 38/319 (12%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 V+E R G + D+ V +K ++ P +A Y Sbjct 13 FGTVFEITNRYTDLNPVGMGAF---GLVCSAIDKLTGQNVAVKKIMKPFSTSVLAKRTYR 69 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H +L + + + + VTE + L L + + Sbjct 70 ELKLLKHLRHENLITLDDIFLSPLEDIYFVTEL-QGTDLHRLLTSR--PLEKQFIQYFTY 126 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + ++H ++ NIL+ + +K+ D G+ V Sbjct 127 QILRGLKYVHSAGVIHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 179 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--------------------FDGEAPL 815 + APE + T +D W G L E+ G P Sbjct 180 RYYRAPE-IMLTWQKYDTEVDLWSVGCILSEMIEGKPLFPGKDHVHQFSIITELLGSPPP 238 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 E+ + LP + +QC EP +L + + L Sbjct 239 DVIETICSENTLRFVQSLPHRDPIPFSERFAQCSHVEPEAIDLLAKMLIFDPKKRISALD 298 Query 876 DVLTVNPDSPASDPTVFHK 894 + + Sbjct 299 ALSHPYMEPYHDPTDEPVC 317 >sp|P24348|LET23_CAEEL Receptor tyrosine-protein kinase let-23 OS=Caenorhabditis elegans OX=6239 GN=let-23 PE=1 SV=3 Length=1323 Score = 223 bits (568), Expect = 5e-58, Method: Composition-based stats. Identities = 83/276 (30%), Positives = 130/276 (47%), Gaps = 22/276 (8%) Query 902 DLGEGHFGKVSLYCYDPTN-DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHII 960 LG G FG V Y P VA+K + D +E + L H++++ Sbjct 890 KLGAGAFGTVFAGIYYPKRAKNVKIPVAIKVFQTDQS--QTDEMLEEATNMFRLRHDNLL 947 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHAQH 1018 K G C + L++V Y PLG+L+++L + ++G + +L+ QI GM YL Q Sbjct 948 KIIGFCMH--DDGLKIVTIYRPLGNLQNFLKLHKENLGAREQVLYCYQIASGMQYLEKQR 1005 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRDLA RNVL+ V+I DFGL+K + + ++ G + W A E ++ + Sbjct 1006 VVHRDLATRNVLVKKFNHVEITDFGLSKILKHDADSITIKS-GKVAIKWLAIEIFSKHCY 1064 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 +ASDVW+FGVT +E++T S M+ + L+ G RL +P Sbjct 1065 THASDVWAFGVTCWEIITFGQS--------------PYQGMSTDSIHNFLKDGNRLSQPP 1110 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 C ++Y + CW + RP FE L K + Sbjct 1111 NCSQDLYQELLRCWMADPKSRPGFEILYERFKEFCK 1146 Score = 206 bits (525), Expect = 8e-53, Method: Composition-based stats. Identities = 65/301 (22%), Positives = 118/301 (39%), Gaps = 37/301 (12%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 N+S++ + + LG G V+ G P R + Sbjct 870 PNMSRICLIPSSELQTKLDKKLGAGAFGTVFAGI-------------------YYPKRAK 910 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 ++ V +KV E A+ M ++ H +L + G C+ +VT Y G Sbjct 911 NVKIPVAIKVFQTDQSQT-DEMLEEATNMFRLRHDNLLKIIGFCMHDDGLKIVTIYRPLG 969 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSP 753 L +L+ + ++ +++ Q+AS + YLE + +VH ++ RN+L+ + Sbjct 970 NLQNFLKLHKENLGAREQVLYCYQIASGMQYLEKQRVVHRDLATRNVLVKKFN------- 1022 Query 754 FIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 ++++D G+ +++ + I WLA E + + A D W FG T EI Sbjct 1023 HVEITDFGLSKILKHDADSITIKSGKVAIKWLAIEIFS--KHCYTHASDVWAFGVTCWEI 1080 Query 808 CFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRD 865 G++P Q S +F + +RL P L +C +P RP F + Sbjct 1081 ITFGQSPYQGMSTDSIHNFLKDGNRLSQPPNCSQDLYQELLRCWMADPKSRPGFEILYER 1140 Query 866 L 866 Sbjct 1141 F 1141 >sp|Q336X9|MPK6_ORYSJ Mitogen-activated protein kinase 6 OS=Oryza sativa subsp. japonica OX=39947 GN=MPK6 PE=2 SV=1 Length=376 Score = 208 bits (529), Expect = 5e-58, Method: Composition-based stats. Identities = 75/328 (23%), Positives = 126/328 (38%), Gaps = 35/328 (11%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHR 941 + + +Y IR +G G +G V N GE VA+K + A Sbjct 29 YNVYGNFFEVSSKYAPPIRPIGRGAYGIVCA----AVNSENGEEVAIKKIGNAFDNHIDA 84 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL---QLVMEYVPLGSLRDYLP-RHSIGL 997 +EI +LR + HE+II K + +V E + L + + Sbjct 85 KRTLREIKLLRHMDHENIIAIKDIIRPPRRDNFNDVYIVSELMD-TDLHQIIRSNQPLTD 143 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRV 1057 F Q+ G+ Y+H+ + +HRDL N+ L+ + +KI DFGLA+ E + Sbjct 144 DHCQYFLYQLLRGLKYVHSANVLHRDLKPSNLFLNANCDLKIADFGLARTTTETD----L 199 Query 1058 REDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-------------- 1102 + ++ APE L ++ A DVWS G L E++T Sbjct 200 MTEYVVTRWYRAPELLLNCSQYTAAIDVWSVGCILGEIVTRQPLFPGRDYIQQLKLITEL 259 Query 1103 --SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 SP L + + + +L + + RL R L++ + S R Sbjct 260 IGSPDDSSLGFLRSDNARRYMKQLPQYPRQDFRL-RFRNMSAGAVDLLEKMLVFDPSRRI 318 Query 1161 TFENLI--PILKTVHEKYQGQA-PSVFS 1185 T + + P L ++H+ + P+ FS Sbjct 319 TVDEALHHPYLASLHDINEEPTCPAPFS 346 Score = 126 bits (316), Expect = 9e-30, Method: Composition-based stats. Identities = 43/242 (18%), Positives = 80/242 (33%), Gaps = 48/242 (20%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 F V K + +G+G V G V Sbjct 35 FFEVSSKYAPPIRPIGRGAYGIVCAAVNSENGE------------------------EVA 70 Query 641 LKVLD---PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN------IMVTEYVE 691 +K + +H D L+ + H ++ + + +R P +V+E ++ Sbjct 71 IKKIGNAFDNHIDAKRT-LREIKLLRHMDHENIIAIKDI-IRPPRRDNFNDVYIVSELMD 128 Query 692 HGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGT 751 L +R + + QL L Y+ + N++H ++ N+ L Sbjct 129 -TDLHQIIRSNQ-PLTDDHCQYFLYQLLRGLKYVHSANVLHRDLKPSNLFLN-------A 179 Query 752 SPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + +K++D G+ + E V + APE L + + A+D W G L EI Sbjct 180 NCDLKIADFGLARTTTETDLMTEYVVTRWYRAPELLLNC-SQYTAAIDVWSVGCILGEIV 238 Query 809 FD 810 Sbjct 239 TR 240 >sp|Q55FT4|TSUA_DICDI Probable serine/threonine-protein kinase tsuA OS=Dictyostelium discoideum OX=44689 GN=tsuA PE=1 SV=1 Length=2247 Score = 224 bits (570), Expect = 6e-58, Method: Composition-based stats. Identities = 70/259 (27%), Positives = 114/259 (44%), Gaps = 26/259 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +GEG FGKV Y TG++VA K + K + +QEIDIL+ L H +II+ Sbjct 11 IGEGSFGKV----YKYRKKFTGQLVACKVISKKGKNEEDILSLRQEIDILKNLSHPNIIQ 66 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + C E++ E LV EY G L + ++ + + Q+ + YLH + I Sbjct 67 FISCFENKNE--FTLVTEYAD-GDLSQIISEEKTLSVDLIQSICYQLVIALNYLHYKKVI 123 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRD+ +N+L+ + +K+ DFG AK + + + APE ++E + Y Sbjct 124 HRDIKPQNILITSGGQIKVCDFGFAKTISSNS---ILLTSLKGTPLYLAPEIIQEQPYDY 180 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 +D+WS G+ LY++L SPP L + LE +P+ Sbjct 181 KADLWSLGIILYQILVG-----SPPFSANSLADLVH---------MTLESNIEIPKELNK 226 Query 1141 PCEVYHLMKNCWETEASFR 1159 ++ L + R Sbjct 227 YPDLVSLFRQLLCKNPDKR 245 Score = 182 bits (461), Expect = 7e-45, Method: Composition-based stats. Identities = 57/279 (20%), Positives = 99/279 (35%), Gaps = 45/279 (16%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 + + +G+G+ VY+ R + V KV+ Sbjct 3 DDYKLIGQIGEGSFGKVYK------------------------YRKKFTGQLVACKVISK 38 Query 647 SHHDIA--LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + L+ + ++ +SH ++ E +VTEY + G L + E+ Sbjct 39 KGKNEEDILSLRQEIDILKNLSHPNIIQFISCFENKNEFTLVTEYAD-GDLSQIISEEK- 96 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + + QL AL+YL K ++H ++ +NIL+ G IK+ D G Sbjct 97 TLSVDLIQSICYQLVIALNYLHYKKVIHRDIKPQNILITSGGQ-------IKVCDFGFAK 149 Query 765 GALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 S +LAPE + D W G L +I G P + S Sbjct 150 TISSNSILLTSLKGTPLYLAPEIIQEQPYDY--KADLWSLGIILYQILV-GSPPFSANSL 206 Query 821 SEKEHFYQRQH-RLPE--PSCPQLATLTSQCLTYEPTQR 856 ++ H + +P+ P L +L Q L P +R Sbjct 207 ADLVHMTLESNIEIPKELNKYPDLVSLFRQLLCKNPDKR 245 >sp|Q8TD08|MK15_HUMAN Mitogen-activated protein kinase 15 OS=Homo sapiens OX=9606 GN=MAPK15 PE=1 SV=1 Length=544 Score = 213 bits (542), Expect = 6e-58, Method: Composition-based stats. Identities = 67/288 (23%), Positives = 115/288 (40%), Gaps = 29/288 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTL-YHEHII 960 LG+G +G V + + TGE+VA+K + A +EI +L+ H +II Sbjct 19 LGQGAYGIV----WKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGDHPNII 74 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHY 1019 + ++ + LV E++ L + + + + Q+ +LH+ H Sbjct 75 SLLDVIRAENDRDIYLVFEFMD-TDLNAVIRKGGLLQDVHVRSIFYQLLRATRFLHSGHV 133 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKA---VPEGHEYYRVREDGDSPVFWYAPECLK-E 1075 +HRD NVLLD + VK+ DFGLA++ +PEG E V E + ++ APE L Sbjct 134 VHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTE-YVATRWYRAPEVLLSS 192 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQS--------------PPTKFLELIGIAQGQMTV 1121 +++ D+WS G L E+L PP +L+ + G Sbjct 193 HRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSGCRAS 252 Query 1122 L--RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + +L + P E L++ R + + Sbjct 253 VLHQLGSRPRQTLDALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQ 300 Score = 136 bits (343), Expect = 3e-32, Method: Composition-based stats. Identities = 52/271 (19%), Positives = 90/271 (33%), Gaps = 53/271 (20%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD---PSHH 649 LGQG V++ DR V +K + Sbjct 17 RQLGQGAYGIVWKAV------------------------DRRTGEVVAIKKIFDAFRDKT 52 Query 650 DIALAFYETASLMSQV-SHTHLAFVHGVCVRGPEN--IMVTEYVEHGPLDVWLRRERGHV 706 D F +L+ + H ++ + V + +V E+++ L+ +R+ G + Sbjct 53 DAQRTF-REITLLQEFGDHPNIISLLDVIRAENDRDIYLVFEFMD-TDLNAVIRKG-GLL 109 Query 707 PMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGA 766 + QL A +L + ++VH + N+LL + +KL D G+ Sbjct 110 QDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLLD-------ANCTVKLCDFGLARSL 162 Query 767 ---------LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + E V + APE L ++ + +D W G L E+ G Sbjct 163 GDLPEGPEDQAVTEYVATRWYRAPEVLLS-SHRYTLGVDMWSLGCILGEML-RGRPLFPG 220 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQC 848 S + +P PS L L S C Sbjct 221 TSTLHQLELILE--TIPPPSEEDLLALGSGC 249 >sp|Q6P4S6|SIK3_MOUSE Serine/threonine-protein kinase SIK3 OS=Mus musculus OX=10090 GN=Sik3 PE=1 SV=4 Length=1369 Score = 223 bits (568), Expect = 6e-58, Method: Composition-based stats. Identities = 69/279 (25%), Positives = 118/279 (42%), Gaps = 29/279 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEI 948 Y + R +G+G+F V T+ T VA+K + K+ ++ +E+ Sbjct 59 MAARIGYYEIDRTIGKGNFAVVK----RATHLVTKAKVAIKIIDKSQLDEENLKKIFREV 114 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQI 1007 I++ L H HII+ E E+ + LV EY G + D+L H + + +QI Sbjct 115 QIMKMLCHPHIIRLYQVME--TERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQI 172 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + + H ++ +HRDL A N+LLD + +KI DFG + G ++ SP + Sbjct 173 VTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPG---QLLKTWCGSPP-Y 228 Query 1068 YAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 APE + ++ D+WS GV LY L+ T+ L Sbjct 229 AAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFD---------------GSTLQNLRA 273 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + G + P E HL+++ + + R + E + Sbjct 274 RVLSG-KFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQI 311 Score = 176 bits (447), Expect = 2e-43, Method: Composition-based stats. Identities = 54/292 (18%), Positives = 95/292 (33%), Gaps = 42/292 (14%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 R+ EI +G+G V V + +V +K Sbjct 62 RIGYYEID--RTIGKGNFAVVKRATHLV------------------------TKAKVAIK 95 Query 643 VLDPS--HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 ++D S + + +M + H H+ ++ V +VTEY G + L Sbjct 96 IIDKSQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLV 155 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 G + +Q+ +A+ + +N+VH ++ N+LL + IK++D Sbjct 156 AH-GRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLD-------ANLNIKIADF 207 Query 761 GVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 G + P+ APE G +D W G L + G P Sbjct 208 GFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYD-GPKVDIWSLGVVLY-VLVCGALPFDG 265 Query 818 RSPSEKE-HFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + + R+P + L L +P +R S I R Sbjct 266 STLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICRHKWM 317 >sp|Q8GRU6|HAR1_LOTJA Leucine-rich repeat receptor-like kinase protein HAR1 OS=Lotus japonicus OX=34305 GN=HAR1 PE=1 SV=1 Length=986 Score = 221 bits (563), Expect = 6e-58, Method: Composition-based stats. Identities = 70/312 (22%), Positives = 123/312 (39%), Gaps = 23/312 (7%) Query 873 NLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL 932 + A + LK+ +G+G G V + G VA+K L Sbjct 671 HRAQAWKLTAFQRLEIKAEDVVECLKEENIIGKGGAGIVYRG-----SMPNGTDVAIKRL 725 Query 933 KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR 992 ++ G++ EI+ L + H +I++ G ++ L+ EY+P GSL ++L Sbjct 726 VGQGSGRNDYGFRAEIETLGKIRHRNIMRLLGYVSNKDTN--LLLYEYMPNGSLGEWLHG 783 Query 993 HS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 + A + G+ Y+H IHRD+ + N+LLD D + DFGLAK Sbjct 784 AKGGHLRWEMRYKIAVEAARGLCYMHHDCSPLIIHRDVKSNNILLDADFEAHVADFGLAK 843 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 + + + S + APE K SDV+SFGV L EL+ Sbjct 844 FLYDPGASQSMSSIAGS-YGYIAPEYAYTLKVDEKSDVYSFGVVLLELIIGRKPVGE-FG 901 Query 1107 KFLELIGIAQGQMTVLR-------LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 ++++G M+ L + +++ P ++++ C + R Sbjct 902 DGVDIVGWVNKTMSELSQPSDTALVLAVVDPRLSG-YPLTSVIHMFNIAMMCVKEMGPAR 960 Query 1160 PTFENLIPILKT 1171 PT ++ +L Sbjct 961 PTMREVVHMLTN 972 Score = 187 bits (475), Expect = 4e-47, Method: Composition-based stats. Identities = 52/358 (15%), Positives = 102/358 (28%), Gaps = 51/358 (14%) Query 562 IIMRGARASPRTLNLSQLSFHRVDQKE----ITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 ++ + + L+ + ++ + + + +G+G VY G Sbjct 664 VVRKRRLHRAQAWKLTAFQRLEIKAEDVVECLKEENIIGKGGAGIVYRG----------- 712 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676 V +K L F + ++ H ++ + G Sbjct 713 --------------SMPNGTDVAIKRLVGQGSGRNDYGFRAEIETLGKIRHRNIMRLLGY 758 Query 677 CVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLENKN---LVH 732 N+++ EY+ +G L WL + GH+ + +A + A L Y+ + ++H Sbjct 759 VSNKDTNLLLYEYMPNGSLGEWLHGAKGGHLRWEMRYKIAVEAARGLCYMHHDCSPLIIH 818 Query 733 GNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL------SREERVERIPWLAPECLPG 786 +V NILL ++D G+ S ++APE Sbjct 819 RDVKSNNILLD-------ADFEAHVADFGLAKFLYDPGASQSMSSIAGSYGYIAPEYA-- 869 Query 787 GANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTS 846 + D + FG LLE+ G P + + E S P L Sbjct 870 YTLKVDEKSDVYSFGVVLLELII-GRKP-VGEFGDGVDIVGWVNKTMSELSQPSDTALVL 927 Query 847 QCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 + + P I + T + + Sbjct 928 AVVDPRLSGYPLTSVIHMFNIAMMCVKEMGPARPTMREVVHMLTNPPQSNTSTQDLIN 985 >sp|Q8INB9|AKT1_DROME RAC serine/threonine-protein kinase OS=Drosophila melanogaster OX=7227 GN=Akt PE=1 SV=3 Length=611 Score = 214 bits (546), Expect = 6e-58, Method: Composition-based stats. Identities = 68/260 (26%), Positives = 102/260 (39%), Gaps = 28/260 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTLYHEHII 960 LG+G FGKV L T ++ A+K LK + Q E +L++ H +I Sbjct 272 LGKGTFGKVILC----REKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHPFLI 327 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHY 1019 K Q L VM+YV G L +L I + + +I + YLH+Q Sbjct 328 SLKYSF--QTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGI 385 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 I+RDL N+LLD D +K+ DFGL K E Y R + + APE L + + Sbjct 386 IYRDLKLENLLLDKDGHIKVADFGLCK---EDITYGRTTKTFCGTPEYLAPEVLDDNDYG 442 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 A D W GV +YE++ + L + + + P Sbjct 443 QAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVK----------------FPRN 486 Query 1140 CPCEVYHLMKNCWETEASFR 1159 E +L+ + R Sbjct 487 ITDEAKNLLAGLLAKDPKKR 506 Score = 163 bits (412), Expect = 1e-40, Method: Composition-based stats. Identities = 71/400 (18%), Positives = 125/400 (31%), Gaps = 56/400 (14%) Query 475 WSTSHPYRLILT-VAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVRELGAAL 533 S S P +L R + + F I V+E R+F EL Sbjct 145 DSASTPSDFLLNNFTVRGCQIMTVDRPKPFTFIIRGLQWTTVIE---RTFAVESELERQQ 201 Query 534 QGCLLRAGDDCFSLRRCCLPQPGETSNLI------IMRGARASPRTLNL---SQLSFHRV 584 +R P E +++ I + ++ + +V Sbjct 202 WTEAIRNVSSRLIDVGEVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKV 261 Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + L LG+GT V + R++ +K+L Sbjct 262 TLENFEFLKVLGKGTFGKV------------------------ILCREKATAKLYAIKIL 297 Query 645 DPS---HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 D + ++ +H L + V +YV G L L Sbjct 298 KKEVIIQKDEVAHTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSH 357 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 ER ++ SAL YL ++ +++ ++ N+LL + G IK++D G Sbjct 358 ERI-FTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDG-------HIKVADFG 409 Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + + + +LAPE L N A+D WG G + E+ G P + Sbjct 410 LCKEDITYGRTTKTFCGTPEYLAPEVLDD--NDYGQAVDWWGTGVVMYEMIC-GRLPFYN 466 Query 818 RSPSEKEHFY-QRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 R + + P + L + L +P +R Sbjct 467 RDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKR 506 >sp|A1A5Q6|SMK_RAT Sperm motility kinase OS=Rattus norvegicus OX=10116 GN=Smok PE=2 SV=1 Length=654 Score = 216 bits (549), Expect = 6e-58, Method: Composition-based stats. Identities = 63/291 (22%), Positives = 114/291 (39%), Gaps = 31/291 (11%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 + + + + LG+G FG+V L ++ T VA+K L Sbjct 7 CQDLRSSPFQEDALTDHYRILASLGQGGFGEVKL----ASHLLTQTKVAIKVLPKS---N 59 Query 940 HRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLA 998 K EI+I+++L H HIIK + +++ +V+E+ G L + + Sbjct 60 KNLLLKSEIEIMKSLDHPHIIKLLHIIDTN--ENIFIVLEHAVGGELLTRIEDFGYLPEE 117 Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 + +Q+ + Y H + IHRD+ N+LLD+ VK+ DFGL+ + G + + Sbjct 118 ECNRLFRQMVLALQYCHQRGIIHRDIKPENILLDHKGNVKLSDFGLSTKIVMGQKLTTL- 176 Query 1059 EDGDSPVFWYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 + + APE + A DVWS GV LY + T C Q + ++ ++ Sbjct 177 ---CGTLPYCAPELFNLNGYDGQAIDVWSLGVVLYYMATGCLPFQGFTYQAIKQKILSGR 233 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 RL +++ ++ RP ++ Sbjct 234 YSVNFRL----------------SPDLWDVIAKLLTVNPRERPRVHEILRF 268 Score = 183 bits (465), Expect = 4e-47, Method: Composition-based stats. Identities = 65/382 (17%), Positives = 117/382 (31%), Gaps = 59/382 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 L+ LGQG V + +V +KVL Sbjct 21 TDHYRILASLGQGGFGEV------------------------KLASHLLTQTKVAIKVLP 56 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 S+ ++ L +M + H H+ + + +V E+ G L + + G+ Sbjct 57 KSNKNLLLK--SEIEIMKSLDHPHIIKLLHIIDTNENIFIVLEHAVGGELLTRI-EDFGY 113 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 +P + +Q+ AL Y + ++H ++ NILL G +KLSD G+ Sbjct 114 LPEEECNRLFRQMVLALQYCHQRGIIHRDIKPENILLDHKG-------NVKLSDFGLSTK 166 Query 766 ALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + +P+ APE A+D W G L + + Sbjct 167 IVMGQKLTTLCGTLPYCAPELFNLNGYD-GQAIDVWSLGVVLYYMATGCLPFQGFTYQAI 225 Query 823 KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 K+ ++ + P L + ++ LT P +RP ILR N +V + Sbjct 226 KQKILSGRYSVNFRLSPDLWDVIAKLLTVNPRERPRVHEILRFNW---LKNENEVSPSSL 282 Query 883 DSPASDPTVFHKRYLKKIRDLGEGH---------FGKVSLYCYDPTNDGTGEMVAVK--- 930 + +G F +V E ++K Sbjct 283 GGNTDSHPDPTILVMMGDMGYEQGQIRESLRERKFDQVMATYLMLREKACSEDKSIKTPH 342 Query 931 ------ALKADCGPQHRSGWKQ 946 LK+ + + Sbjct 343 PTQCAQTLKSTGSTTEKQTTLR 364 >sp|Q8H1D6|RBK1_ARATH Receptor-like cytosolic serine/threonine-protein kinase RBK1 OS=Arabidopsis thaliana OX=3702 GN=RBK1 PE=1 SV=1 Length=467 Score = 211 bits (536), Expect = 6e-58, Method: Composition-based stats. Identities = 76/340 (22%), Positives = 135/340 (40%), Gaps = 33/340 (10%) Query 842 ATLTSQCLT-YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 LT + L +P PS + + + + + Sbjct 105 YELTRKNLRRKQPKLTPSESAFTCEAFFMAKPSWRNFTYEELAVATDYFNPENM------ 158 Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEIDILRTLYHEH 958 +G+G +V GE VA+K L + + + E+ I+ + H + Sbjct 159 --IGKGGHAEVYKGVL-----INGETVAIKKLMSHAKEEEERVSDFLSELGIIAHVNHPN 211 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL--PRHSIGLAQLLLFAQQICEGMAYLHA 1016 + +G D+G L V+EY P GSL L + A I +G++YLH Sbjct 212 AARLRGFSSDRG---LHFVLEYAPYGSLASMLFGSEECLEWKIRYKVALGIADGLSYLHN 268 Query 1017 ---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 + IHRD+ A N+LL++D +I DFGLAK +PE ++ V + + APE Sbjct 269 ACPRRIIHRDIKASNILLNHDYEAQISDFGLAKWLPENWPHHVV-FPIEGTFGYLAPEYF 327 Query 1074 KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 DV++FGV L E++T + + + ++ A+ + + ++++ Sbjct 328 MHGIVDEKIDVFAFGVLLLEIITSRRAVDTASRQ--SIVAWAKPFLEKNSMEDIVDPRLG 385 Query 1134 LPRPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILK 1170 P E+ +M C A+ RP L+ +L+ Sbjct 386 NMFN---PTEMQRVMLTASMCVHHIAAMRPDMTRLVQLLR 422 Score = 168 bits (426), Expect = 2e-43, Method: Composition-based stats. Identities = 62/322 (19%), Positives = 104/322 (32%), Gaps = 64/322 (20%) Query 567 ARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDP 626 A+ S R +L+ V + +G+G VY+G L + Sbjct 134 AKPSWRNFTYEELA---VATDYFNPENMIGKGGHAEVYKGVLINGET------------- 177 Query 627 LVPGRDRGQELRVVLKVL---DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 V +K L + F +++ V+H + A + G Sbjct 178 ------------VAIKKLMSHAKEEEERVSDFLSELGIIAHVNHPNAARLRGFSSDRG-L 224 Query 684 IMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNI 740 V EY +G L L + + VA +A LSYL N + ++H ++ NI Sbjct 225 HFVLEYAPYGSLASMLFGSEECLEWKIRYKVALGIADGLSYLHNACPRRIIHRDIKASNI 284 Query 741 LLARLGLAEGTSPFIKLSDPGVGL-GALSREERV-----ERIPWLAPECLPGGANSLSTA 794 LL A+ +SD G+ + V +LAPE G + Sbjct 285 LLNHDYEAQ-------ISDFGLAKWLPENWPHHVVFPIEGTFGYLAPEYFMHGI--VDEK 335 Query 795 MDKWGFGATLLEICFDGEA--------------PLQSRSPSEKEHFYQRQHRLPEPSCPQ 840 +D + FG LLEI A P ++ E + + + Sbjct 336 IDVFAFGVLLLEIITSRRAVDTASRQSIVAWAKPFLEKNSMEDIVDPRLGNMFNPTEMQR 395 Query 841 LATLTSQCLTYEPTQRPSFRTI 862 + S C+ + RP + Sbjct 396 VMLTASMCVHHIAAMRPDMTRL 417 >sp|Q54G43|SHKE_DICDI Dual specificity protein kinase shkE OS=Dictyostelium discoideum OX=44689 GN=shkE PE=3 SV=1 Length=710 Score = 217 bits (552), Expect = 7e-58, Method: Composition-based stats. Identities = 62/274 (23%), Positives = 112/274 (41%), Gaps = 26/274 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G +GKV K +K E++I++ ++H +++ Sbjct 243 LGGGAYGKVYKATCRGKKVAVKVP-----KKQTLSESELKSFKNEVEIMKQIFHPNVVLC 297 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI---GLAQLLLFAQQICEGMAYLHA-QH 1018 G C G+ + +V E + L + + L + + G+ +LH + Sbjct 298 LGACTKPGK--VMIVSELMQ-TDLEKLIHSSEVEPPPLYERMKMCLDAALGINWLHGICN 354 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 IHRDL N+++ D+ VKIGDFG ++ + G + + APE + +++F Sbjct 355 IIHRDLKLANLMISKDKTVKIGDFGFSQVIKTGTTLSDQKGP-KGTALYMAPEVMMKHEF 413 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 +DV+SFG+ LYE+ T + I + R P PD Sbjct 414 NEKADVYSFGLILYEMATCEELFPEYSEIDPFYDAICN-------------KKLRPPIPD 460 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 P + L++ CW+ + + RP+F + + V Sbjct 461 SFPKSLKTLIQKCWDHDPNKRPSFNEVTQRMNEV 494 Score = 187 bits (474), Expect = 6e-48, Method: Composition-based stats. Identities = 52/316 (16%), Positives = 112/316 (35%), Gaps = 47/316 (15%) Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 R+S R ++ + + LG G VY+ R + K Sbjct 215 EKKRSSSRHSGPPEIPPEEIKFD--VKTDLLGGGAYGKVYKATCRGKKVAVKVPKKQTL- 271 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 +F +M Q+ H ++ G C + + + Sbjct 272 -----------------------SESELKSFKNEVEIMKQIFHPNVVLCLGACTKPGKVM 308 Query 685 MVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLEN-KNLVHGNVCGRNILL 742 +V+E ++ L+ + P+ +M + A +++L N++H ++ N+++ Sbjct 309 IVSELMQ-TDLEKLIHSSEVEPPPLYERMKMCLDAALGINWLHGICNIIHRDLKLANLMI 367 Query 743 ARLGLAEGTSPFIKLSDPGV------GLGALSREERVERIPWLAPECLPGGANSLSTAMD 796 ++ +K+ D G G ++ ++APE + + + D Sbjct 368 SK-------DKTVKIGDFGFSQVIKTGTTLSDQKGPKGTALYMAPEVMM--KHEFNEKAD 418 Query 797 KWGFGATLLEICFDGE-APLQSRSPSEKEHFYQRQHR--LPEPSCPQLATLTSQCLTYEP 853 + FG L E+ E P S + ++ R +P+ L TL +C ++P Sbjct 419 VYSFGLILYEMATCEELFPEYSEIDPFYDAICNKKLRPPIPDSFPKSLKTLIQKCWDHDP 478 Query 854 TQRPSFRTILRDLTRL 869 +RPSF + + + + Sbjct 479 NKRPSFNEVTQRMNEV 494 >sp|P43292|SRK2G_ARATH Serine/threonine-protein kinase SRK2G OS=Arabidopsis thaliana OX=3702 GN=SRK2G PE=1 SV=2 Length=353 Score = 207 bits (527), Expect = 7e-58, Method: Composition-based stats. Identities = 75/276 (27%), Positives = 117/276 (42%), Gaps = 26/276 (9%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 ++DLG G+FG L + T E+VA+K + + G + +EI R+ Sbjct 1 MDKYDVVKDLGAGNFGVARLL----RHKDTKELVAMKYI--ERGRKIDENVAREIINHRS 54 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMA 1012 L H +II++K L +VMEY G L D + A+ F QQ+ G+ Sbjct 55 LKHPNIIRFKEVILTPTH--LAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVD 112 Query 1013 YLHAQHYIHRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 Y H+ HRDL N LLD L+KI DFG +K + R + +P + AP Sbjct 113 YCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSK---SSILHSRPKSTVGTPA-YIAP 168 Query 1071 ECLKEYKFYYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 E L ++ +DVWS GVTLY +L + P I + ++ + + Sbjct 169 EVLSRREYDGKHADVWSCGVTLYVMLVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYV- 227 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 E HL+ + T ++ R T + + Sbjct 228 ---------HISQECKHLLSRIFVTNSAKRITLKEI 254 Score = 147 bits (372), Expect = 2e-37, Method: Composition-based stats. Identities = 43/250 (17%), Positives = 79/250 (32%), Gaps = 17/250 (7%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 R + + V +K ++ I + H ++ V + +V EY Sbjct 22 RHKDTKELVAMKYIERG-RKIDENVAREIINHRSLKHPNIIRFKEVILTPTHLAIVMEYA 80 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L + G A QQL + Y + + H ++ N LL Sbjct 81 SGGELFDRI-CTAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLD-----GS 134 Query 751 TSPFIKLSDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +P +K+ D G ++ + V ++APE L D W G TL + Sbjct 135 PAPLLKICDFGYSKSSILHSRPKSTVGTPAYIAPEVLSRREYD-GKHADVWSCGVTLYVM 193 Query 808 CFDGEAPLQSRSPSE----KEHFYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRT 861 P + Q+++P+ + L S+ +R + + Sbjct 194 LVGAYPFEDPNDPKNFRKTIQRIMAVQYKIPDYVHISQECKHLLSRIFVTNSAKRITLKE 253 Query 862 ILRDLTRLQP 871 I L+ Sbjct 254 IKNHPWYLKN 263 >sp|Q91ZR4|NEK8_MOUSE Serine/threonine-protein kinase Nek8 OS=Mus musculus OX=10090 GN=Nek8 PE=1 SV=1 Length=698 Score = 216 bits (551), Expect = 7e-58, Method: Composition-based stats. Identities = 66/269 (25%), Positives = 120/269 (45%), Gaps = 30/269 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V L ++V +K + + + R + E +L+ L H ++I+ Sbjct 10 VGRGAFGIVHLCLRKA----DQKLVILKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIE 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018 Y + +K+L + MEY P G+L +++ + + +L F QI + ++H Sbjct 66 YYENFLE--DKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHL 123 Query 1019 YIHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL +N+LLD +VKIGDFG++K + + Y V + +PE + Sbjct 124 ILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTV----VGTPCYISPELCEGKP 179 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + SD+W+ G LYEL + + ++ L L + G P Sbjct 180 YNQKSDIWALGCVLYELASLKRAFEAANLPALVL---------------KIMSGTFAPIS 224 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 D+ E+ L+ + E + RP +++ Sbjct 225 DRYSPELRQLVLSLLSLEPAQRPPLSHIM 253 Score = 164 bits (416), Expect = 1e-40, Method: Composition-based stats. Identities = 45/292 (15%), Positives = 101/292 (35%), Gaps = 39/292 (13%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ ++ +G+G V+ + + + V+LK + Sbjct 1 MEKYERIRVVGRGAFGIVHLCLRKAD------------------------QKLVILKQIP 36 Query 646 PSHH--DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 + A ++ ++H ++ + + ++ EY G L ++++ Sbjct 37 VEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRC 96 Query 704 GH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + + Q+ AL ++ ++H ++ +NILL + +K+ D G+ Sbjct 97 NSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKH------RMVVKIGDFGI 150 Query 763 GLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 S+ V +++PE G + D W G L E+ A + Sbjct 151 SKILSSKSKAYTVVGTPCYISPELCEG--KPYNQKSDIWALGCVLYELASLKRAFEAANL 208 Query 820 PSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P+ + + P+L L L+ EP QRP I+ ++ Sbjct 209 PALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIR 260 >sp|Q501Q9|MK15_XENLA Mitogen-activated protein kinase 15 OS=Xenopus laevis OX=8355 GN=mapk15 PE=1 SV=1 Length=586 Score = 214 bits (545), Expect = 7e-58, Method: Composition-based stats. Identities = 68/299 (23%), Positives = 118/299 (39%), Gaps = 27/299 (9%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEID 949 + + LG+G +G V + + +GE+VAVK + A +EI Sbjct 8 DHISQKYDIKKRLGKGAYGIV----WKAIDRKSGEIVAVKKIFDAFRNRTDAQRTFREIM 63 Query 950 ILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQI 1007 L+ H +IIK Q +K + LV E++ L + + ++ + Q+ Sbjct 64 FLQEFGEHPNIIKLLNVIRAQNDKDIYLVFEHME-TDLHAVIKKGNLLKDIHMRYILYQL 122 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYR--VREDGDSPV 1065 + ++H+ + IHRD N+LLD D LVK+ DFGLA+++ + E + + Sbjct 123 LKATKFIHSGNVIHRDQKPSNILLDGDCLVKLCDFGLARSLYQIQEDVGNPALTEYVATR 182 Query 1066 FWYAPECLK-EYKFYYASDVWSFGVTLYELLTHCDSS----------------QSPPTKF 1108 ++ APE L ++ D+WS G L E+L + P + Sbjct 183 WYRAPEILLASNRYTKGVDMWSVGCILGEMLLGKPLFPGTSTINQIERIMSIIEPPTHED 242 Query 1109 LELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + I G + R++ + P CP E L+ R T E + Sbjct 243 IVSIKSEYGASVISRMSSKHKVPMAELFPASCPREALDLLSKLLVFNPGKRLTAEEALE 301 Score = 135 bits (340), Expect = 1e-31, Method: Composition-based stats. Identities = 44/269 (16%), Positives = 89/269 (33%), Gaps = 52/269 (19%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 ++ ++ H + +I LG+G V++ DR Sbjct 1 MSGPEVEDHISQKYDIK--KRLGKGAYGIVWKAI------------------------DR 34 Query 634 GQELRVVLKVLD---PSHHDIALAFYETASLMSQV-SHTHLAFVHGVCV--RGPENIMVT 687 V +K + + D F + + H ++ + V + +V Sbjct 35 KSGEIVAVKKIFDAFRNRTDAQRTF-REIMFLQEFGEHPNIIKLLNVIRAQNDKDIYLVF 93 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 E++E L +++ + + + QL A ++ + N++H + NILL Sbjct 94 EHME-TDLHAVIKKGNLLKDIHMRY-ILYQLLKATKFIHSGNVIHRDQKPSNILLD---- 147 Query 748 AEGTSPFIKLSDPGVGLGALSREERVERIP---------WLAPECLPGGANSLSTAMDKW 798 +KL D G+ +E V + APE L +N + +D W Sbjct 148 ---GDCLVKLCDFGLARSLYQIQEDVGNPALTEYVATRWYRAPEILL-ASNRYTKGVDMW 203 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFY 827 G L E+ + + ++ E Sbjct 204 SVGCILGEMLLGKPLFPGTSTINQIERIM 232 >sp|E9Q3S4|M3K19_MOUSE Mitogen-activated protein kinase kinase kinase 19 OS=Mus musculus OX=10090 GN=Map3k19 PE=3 SV=1 Length=1311 Score = 223 bits (567), Expect = 7e-58, Method: Composition-based stats. Identities = 70/287 (24%), Positives = 120/287 (42%), Gaps = 29/287 (10%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG-----PQHRSGW 944 + K LG G +G V G+++AVK + D + Sbjct 1037 NHEEAIFWTKGEILGRGAYGTVYCG-----LTSLGQLIAVKQVALDTSDKLATEKEYRKL 1091 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLF 1003 ++E+D+L+ L H +I+ Y G C + E +L + ME+VP GS+ + R + + Sbjct 1092 QEEVDLLKALKHVNIVAYLGTCLE--ENTLSIFMEFVPGGSISSIINRFGPLPEMVFCKY 1149 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE---GHEYYRVRED 1060 +QI +G+AYLH +HRD+ NV+L ++K+ DFG AK + + + + Sbjct 1150 TRQILQGVAYLHDNCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHSDMLKS 1209 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 +W APE + E + SD+WS G T++E+ T P + + Sbjct 1210 MRGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKP----PLASMDRMAAMFYIGAH 1265 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 RG P P + ++ C + RP+ L+ Sbjct 1266 ---------RGLMPPLPARFSEPAADFVRLCLTRDQHERPSALQLLK 1303 Score = 180 bits (457), Expect = 1e-44, Method: Composition-based stats. Identities = 69/328 (21%), Positives = 113/328 (34%), Gaps = 53/328 (16%) Query 555 PGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSG 614 E + L S ++LN + F T+ LG+G VY G + Sbjct 1017 YDEENFLTSNEKKTLSDKSLNHEEAIFW-------TKGEILGRGAYGTVYCGLTSLGQLI 1069 Query 615 DPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVH 674 ++ +D D L ++ E L+ + H ++ Sbjct 1070 AVKQVALDTSDKLATEKEY-------------------RKLQEEVDLLKALKHVNIVAYL 1110 Query 675 GVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGN 734 G C+ + E+V G + + G +P +Q+ ++YL + +VH + Sbjct 1111 GTCLEENTLSIFMEFVPGGSISSII-NRFGPLPEMVFCKYTRQILQGVAYLHDNCVVHRD 1169 Query 735 VCGRNILLARLGLAEGTSPFIKLSDPGVGL--------GALSR--EERVERIPWLAPECL 784 + G N++L G+ IKL D G G S + W+APE + Sbjct 1170 IKGNNVMLMPTGI-------IKLIDFGCAKRLAWAGLNGTHSDMLKSMRGTPYWMAPEVI 1222 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-----LPEPSCP 839 + D W G T+ E+ G+ PL S FY HR LP Sbjct 1223 --NESGYGRKSDIWSIGCTVFEMA-TGKPPLASMD-RMAAMFYIGAHRGLMPPLPARFSE 1278 Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLT 867 A CLT + +RPS +L+ Sbjct 1279 PAADFVRLCLTRDQHERPSALQLLKHSF 1306 >sp|G5EFU0|PK2_CAEEL Serine/threonine-protein kinase pak-2 OS=Caenorhabditis elegans OX=6239 GN=pak-2 PE=2 SV=1 Length=522 Score = 212 bits (540), Expect = 7e-58, Method: Composition-based stats. Identities = 67/301 (22%), Positives = 116/301 (39%), Gaps = 23/301 (8%) Query 859 FRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDP 918 T + + + L + +GEG G V Sbjct 193 PSTPQAMRQQPKCTEGVSDEEFRNALKFVVDGTDPRSDLTDYKQIGEGSTGVVEAAY--- 249 Query 919 TNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVM 978 T ++VAVK + Q R E+ ILR H +I+++ + L +VM Sbjct 250 -KISTKQIVAVKRMNLRK-QQRRELLFNEVSILRQYQHPNIVRF--FSSHLVDDELWVVM 305 Query 979 EYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVK 1038 E++ GSL D + + Q+ ++Q+ + +LHA+ IHRD+ + ++LL D VK Sbjct 306 EFMEGGSLTDIVTATRMTEPQIATISRQVLGALDFLHARKVIHRDIKSDSILLKRDGTVK 365 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 + DFG + E R +W A E + + +D+WSFG+ L E++ Sbjct 366 LTDFGFCGQLSE---EVPRRRSLVGTPYWTAAEVIAREPYDTRADIWSFGIMLIEMVEGE 422 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASF 1158 + Q + R+ + E R R K E+ L+ +C + + Sbjct 423 PPFFND-----------QPFQAMKRIRD--EHEARFSRHAKVSVELSELLSHCIVKDVNK 469 Query 1159 R 1159 R Sbjct 470 R 470 Score = 186 bits (473), Expect = 4e-49, Method: Composition-based stats. Identities = 59/338 (17%), Positives = 111/338 (33%), Gaps = 45/338 (13%) Query 539 RAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQG 598 R + PQ G L + + ++T +G+G Sbjct 182 RTTTPQLQPKSPSTPQAMRQQPKC-TEGVSDEEFRNALKFVVDGTDPRSDLTDYKQIGEG 240 Query 599 TRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYET 658 + V + V +K ++ + Sbjct 241 STGVV------------------------EAAYKISTKQIVAVKRMNLRKQQRRELLFNE 276 Query 659 ASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQL 718 S++ Q H ++ + E +V E++E G L + R + +++Q+ Sbjct 277 VSILRQYQHPNIVRFFSSHLVDDELWVVMEFMEGGSLTDIVTATR--MTEPQIATISRQV 334 Query 719 ASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG----VGLGALSREERVE 774 AL +L + ++H ++ +ILL R G +KL+D G + R V Sbjct 335 LGALDFLHARKVIHRDIKSDSILLKRDG-------TVKLTDFGFCGQLSEEVPRRRSLVG 387 Query 775 RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-- 832 W A E + T D W FG L+E+ +GE P + P + + +H Sbjct 388 TPYWTAAEVIA--REPYDTRADIWSFGIMLIEMV-EGEPPFFNDQPFQAMKRIRDEHEAR 444 Query 833 --LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 +L+ L S C+ + +R + +LR Sbjct 445 FSRHAKVSVELSELLSHCIVKDVNKRWPAKDLLRHPFF 482 >sp|Q61526|ERBB3_MOUSE Receptor tyrosine-protein kinase erbB-3 OS=Mus musculus OX=10090 GN=Erbb3 PE=1 SV=2 Length=1339 Score = 223 bits (567), Expect = 7e-58, Method: Composition-based stats. Identities = 89/272 (33%), Positives = 139/272 (51%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + V +K ++ G Q + + +L H HI++ Sbjct 713 LGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRL 772 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C SLQLV +Y+PLGSL D++ +H ++G LL + QI +GM YL + Sbjct 773 LGLC---PGSSLQLVTQYLPLGSLLDHVRQHRETLGPQLLLNWGVQIAKGMYYLEEHSMV 829 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLA RNV+L + V++ DFG+A +P + + + +P+ W A E + K+ + Sbjct 830 HRDLALRNVMLKSPSQVQVADFGVADLLPP-DDKQLLHSEAKTPIKWMALESIHFGKYTH 888 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + + + +LLE+GERL +P C Sbjct 889 QSDVWSYGVTVWELMTFG--------------AEPYAGLRLAEIPDLLEKGERLAQPQIC 934 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW + + RPTF+ L + Sbjct 935 TIDVYMVMVKCWMIDENIRPTFKELANEFTRM 966 Score = 201 bits (511), Expect = 4e-51, Method: Composition-based stats. Identities = 67/366 (18%), Positives = 131/366 (36%), Gaps = 39/366 (11%) Query 520 GRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQL 579 + + L+ G + R + L + +++ Sbjct 638 SKPHLVIAVTVGLTVIFLILGGSFLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKANKV 697 Query 580 SFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRV 639 + E+ +L LG G V++G EG ++ V Sbjct 698 LARIFKETELRKLKVLGSGVFGTVHKGIWIPEGESI--------------------KIPV 737 Query 640 VLKVL-DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +KV+ D S A + + + H H+ + G+C G +VT+Y+ G L Sbjct 738 CIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLCP-GSSLQLVTQYLPLGSLLDH 796 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 +R+ R + + Q+A + YLE ++VH ++ RN++L + ++++ Sbjct 797 VRQHRETLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVML-------KSPSQVQVA 849 Query 759 DPGVGLGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGE 812 D GV + E I W+A E + G + D W +G T+ E+ G Sbjct 850 DFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFG--KYTHQSDVWSYGVTVWELMTFGA 907 Query 813 APLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 P +E ++ RL P+ + + +C + RP+F+ + + TR+ Sbjct 908 EPYAGLRLAEIPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMA 967 Query 871 PHNLAD 876 Sbjct 968 RDPPRY 973 >sp|Q751E8|PHO85_EREGS Negative regulator of the PHO system OS=Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=PHO85 PE=3 SV=2 Length=301 Score = 205 bits (521), Expect = 7e-58, Method: Composition-based stats. Identities = 69/314 (22%), Positives = 132/314 (42%), Gaps = 40/314 (13%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDI 950 + K++ LG G + V Y N TG VA+K +K D S +EI + Sbjct 1 MTSTSQFKQLERLGNGTYATV----YKGLNKTTGLYVALKEVKLDSEEGTPSTAIREISL 56 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-------SIGLAQLLLF 1003 ++ L HE+I++ E L LV E++ L+ ++ + L+ + F Sbjct 57 MKELKHENIVRLYDVI--HTENKLTLVFEFMDN-DLKKFMDSRLDREMPRGLELSLVKYF 113 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 Q+ +G+A+ H +HRDL +N+L++N +K+GDFGLA+A Sbjct 114 QWQLLQGVAFCHENRILHRDLKPQNLLINNKGQLKLGDFGLARAFGIP---VNTFSSEVV 170 Query 1064 PVFWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQSPPTK-----FLELIGIAQG 1117 +++ AP+ L + + + D+WS G L E++ E +G Sbjct 171 TLWYRAPDVLMGSRTYCTSIDIWSCGCILAEMIMGKALFPGTNDDEQLKLIFETMGTPTE 230 Query 1118 QMTVLRLTELLERGERLP-RP-------------DKCPCEVYHLMKNCWETEASFRPTFE 1163 Q T + +++L + ++P P ++ + +L++ + S R + + Sbjct 231 Q-TWVGVSQLPKYNPQIPLYPNKDIKQLLQATTKEQISDVLVNLIQGLLQLNPSMRLSAQ 289 Query 1164 NLIPILKTVHEKYQ 1177 + + E+Y Sbjct 290 QALSH--PLFEEYH 301 Score = 166 bits (419), Expect = 3e-44, Method: Composition-based stats. Identities = 46/270 (17%), Positives = 97/270 (36%), Gaps = 43/270 (16%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + QL LG GT VY+G + G L V LK + Sbjct 3 STSQFKQLERLGNGTYATVYKGLNKTTG------------------------LYVALKEV 38 Query 645 DPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL---- 699 + SLM ++ H ++ ++ V + +V E++++ L ++ Sbjct 39 KLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDN-DLKKFMDSRL 97 Query 700 -RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 R + ++ QL +++ ++H ++ +N+L+ G +KL Sbjct 98 DREMPRGLELSLVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNKGQ-------LKLG 150 Query 759 DPGVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 D G+ + V + + AP+ L G+ + T++D W G L E+ Sbjct 151 DFGLARAFGIPVNTFSSEVVTLWYRAPDVLM-GSRTYCTSIDIWSCGCILAEMIMGKALF 209 Query 815 LQSRSPSEKEHFYQRQHRLPEPSCPQLATL 844 + + + ++ E + ++ L Sbjct 210 PGTNDDEQLKLIFETMGTPTEQTWVGVSQL 239 >sp|Q6U1I9|SGK1_CHICK Serine/threonine-protein kinase Sgk1 OS=Gallus gallus OX=9031 GN=SGK1 PE=2 SV=1 Length=432 Score = 209 bits (533), Expect = 8e-58, Method: Composition-based stats. Identities = 66/338 (20%), Positives = 118/338 (35%), Gaps = 29/338 (9%) Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885 F +++ ++AT + C E + + + Sbjct 28 FMKQRRMGLNDFIQKIATNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINLG 87 Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSG 943 S ++ +G+G FGKV L + + AVK L KA + Sbjct 88 PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEE----QFYAVKVLQKKAILKKKEEKH 143 Query 944 WKQEID-ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLL 1001 E + +L+ + H ++ Q L V++Y+ G L +L R + Sbjct 144 IMSERNVLLKNVKHPFLVGLH--FSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRAR 201 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 +A +I + YLH+ + ++RDL N+LLD+ + + DFGL K E E+ Sbjct 202 FYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCK---ENIEHNGTTSTF 258 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 + APE L + + D W G LYE+L + T Sbjct 259 CGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPF--------------YSRNTA 304 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 +L + +L HL++ + + + R Sbjct 305 EMYDNILNKPLQLK--PNITNSARHLLEGLLQKDRTKR 340 Score = 162 bits (410), Expect = 1e-41, Method: Composition-based stats. Identities = 68/314 (22%), Positives = 109/314 (35%), Gaps = 45/314 (14%) Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 PQ E N + + +NL S + L +G+G+ V Sbjct 63 QPQEPELMN-ANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKV-------- 113 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETAS-LMSQVSH 667 + R + +E +KVL + L+ V H Sbjct 114 ----------------LLARHKAEEQFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 157 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 L +H + V +Y+ G L L+RER + + A ++ASAL YL + Sbjct 158 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARF-YAAEIASALGYLHS 216 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREERVERIPWLAPEC 783 N+V+ ++ NILL G I L+D G+ + + +LAPE Sbjct 217 LNIVYRDLKPENILLDSQG-------HIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEV 269 Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPSCPQLA 842 L +D W GA L E+ G P SR+ +E + + +L Sbjct 270 LH--KQPYDRTVDWWCLGAVLYEML-YGLPPFYSRNTAEMYDNILNKPLQLKPNITNSAR 326 Query 843 TLTSQCLTYEPTQR 856 L L + T+R Sbjct 327 HLLEGLLQKDRTKR 340 >sp|P32485|HOG1_YEAST Mitogen-activated protein kinase HOG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=HOG1 PE=1 SV=2 Length=435 Score = 209 bits (533), Expect = 8e-58, Method: Composition-based stats. Identities = 62/309 (20%), Positives = 107/309 (35%), Gaps = 29/309 (9%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-K 933 + + +G G FG V T+ T + VA+K + K Sbjct 1 MTTNEEFIRTQIFGTVFEITNRYNDLNPVGMGAFGLVC----SATDTLTSQPVAIKKIMK 56 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993 +E+ +L+ L HE++I + E + V E L L Sbjct 57 PFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLED-IYFVTEL-QGTDLHRLLQTR 114 Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + + F QI G+ Y+H+ IHRDL N+L++ + +KI DFGLA+ Sbjct 115 PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMT 174 Query 1054 YYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTK 1107 Y S ++ APE + K+ D+WS G E++ + Sbjct 175 GY------VSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSI 228 Query 1108 FLELIGIAQGQMTVLRLTELLER-----GERLPRP-----DKCPCEVYHLMKNCWETEAS 1157 +L+G + +E + R P P + L++ + Sbjct 229 ITDLLGSPPKDVINTICSENTLKFVTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPK 288 Query 1158 FRPTFENLI 1166 R T + + Sbjct 289 KRITAADAL 297 Score = 137 bits (345), Expect = 4e-33, Method: Composition-based stats. Identities = 36/213 (17%), Positives = 69/213 (32%), Gaps = 18/213 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 V+E R G + D V +K ++ P +A Y Sbjct 13 FGTVFEITNRYNDLNPVGMGAF---GLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYR 69 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H +L + + + + VTE + L L+ + + Sbjct 70 ELKLLKHLRHENLICLQDIFLSPLEDIYFVTEL-QGTDLHRLLQTR--PLEKQFVQYFLY 126 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + ++H ++ NIL+ + +K+ D G+ V Sbjct 127 QILRGLKYVHSAGVIHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 179 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + APE + +D W G E+ Sbjct 180 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEMI 211 >sp|Q9SKB2|SBIR1_ARATH Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 OS=Arabidopsis thaliana OX=3702 GN=SOBIR1 PE=1 SV=1 Length=641 Score = 215 bits (548), Expect = 8e-58, Method: Composition-based stats. Identities = 71/294 (24%), Positives = 117/294 (40%), Gaps = 29/294 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-------------KADCGPQHRSGWKQEID 949 +G G G+V +N G+++AVK + + + + EI+ Sbjct 353 IGRGGCGEVFKAELPGSN---GKIIAVKKVIQPPKDADELTDEDSKFLNKKMRQIRSEIN 409 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSIGLAQLLLFA 1004 + + H +++ + LV EY+ GSL+D L + A Sbjct 410 TVGHIRHRNLLPLLAHVSRP--ECHYLVYEYMEKGSLQDILTDVQAGNQELMWPARHKIA 467 Query 1005 QQICEGMAYLH---AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 I G+ YLH IHRDL NVLLD+D +I DFGLAKA+P+ + Sbjct 468 LGIAAGLEYLHMDHNPRIIHRDLKPANVLLDDDMEARISDFGLAKAMPDAVTHITTSHVA 527 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS--PPTKFLELIGIAQGQM 1119 V + APE + +KF D++SFGV L L+ S T + LI + + Sbjct 528 -GTVGYIAPEFYQTHKFTDKCDIYSFGVILGILVIGKLPSDEFFQHTDEMSLIKWMRNII 586 Query 1120 TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVH 1173 T + ++ D+ V + C + RP +++ +L + Sbjct 587 TSENPSLAIDPKLMDQGFDEQMLLVLKIACYCTLDDPKQRPNSKDVRTMLSQIK 640 Score = 185 bits (469), Expect = 1e-47, Method: Composition-based stats. Identities = 58/345 (17%), Positives = 117/345 (34%), Gaps = 56/345 (16%) Query 564 MRGARASPRTLNLSQL-----SFHRVDQKE-ITQLSHLGQGTRTNVYEGRL-RVEGSGDP 616 +RG+ P S L ++ +E + L +G+G V++ L G Sbjct 316 IRGSEKPPGPSIFSPLIKKAEDLAFLENEEALASLEIIGRGGCGEVFKAELPGSNGKIIA 375 Query 617 EEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGV 676 + + D K L+ + + + H +L + Sbjct 376 VKKVIQPPKDADELTDEDS------KFLNKK----MRQIRSEINTVGHIRHRNLLPLLAH 425 Query 677 CVRGPENIMVTEYVEHGPLDVWLRR-ERGHVPMAW--KMVVAQQLASALSYL---ENKNL 730 R + +V EY+E G L L + G+ + W + +A +A+ L YL N + Sbjct 426 VSRPECHYLVYEYMEKGSLQDILTDVQAGNQELMWPARHKIALGIAAGLEYLHMDHNPRI 485 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG------ALSREERVERIPWLAPECL 784 +H ++ N+LL ++SD G+ ++ + ++APE Sbjct 486 IHRDLKPANVLLD-------DDMEARISDFGLAKAMPDAVTHITTSHVAGTVGYIAPEFY 538 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLA-- 842 + + D + FG L + + +++ + + P LA Sbjct 539 QT--HKFTDKCDIYSFGVILGILVIGKLPSDEFFQHTDEMSLIKWMRNIITSENPSLAID 596 Query 843 -TLTSQ---------------CLTYEPTQRPSFRTILRDLTRLQP 871 L Q C +P QRP+ + + L++++ Sbjct 597 PKLMDQGFDEQMLLVLKIACYCTLDDPKQRPNSKDVRTMLSQIKH 641 >sp|Q6ZI44|SAPK6_ORYSJ Serine/threonine-protein kinase SAPK6 OS=Oryza sativa subsp. japonica OX=39947 GN=SAPK6 PE=1 SV=1 Length=365 Score = 207 bits (527), Expect = 8e-58, Method: Composition-based stats. Identities = 72/270 (27%), Positives = 109/270 (40%), Gaps = 30/270 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 D+G G+FG L N T E+VA+K + G + +EI R+L H +II+ Sbjct 9 DIGSGNFGVARLM----RNRETKELVAMKYIPR--GLKIDENVAREIINHRSLRHPNIIR 62 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 +K L +VMEY G L D + + F QQ+ G++Y H Sbjct 63 FKEVVLTPTH--LAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYCHFMQIC 120 Query 1021 HRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N LLD +KI DFG +K + + + APE L ++ Sbjct 121 HRDLKLENTLLDGSPAPRLKICDFGYSK----SSLLHSKPKSTVGTPAYIAPEVLSRREY 176 Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSP--PTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 +DVWS GVTLY +L + P P F + IG ++ ++P Sbjct 177 DGKMADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIG------------RIVSIQYKIP 224 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 + L+ + + R T + Sbjct 225 EYVHISQDCRQLLSRIFVANPAKRITIREI 254 Score = 155 bits (391), Expect = 1e-39, Method: Composition-based stats. Identities = 51/295 (17%), Positives = 84/295 (28%), Gaps = 41/295 (14%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ L +G G R+R + V +K + Sbjct 1 MEKYELLKDIGSGNFG------------------------VARLMRNRETKELVAMKYI- 35 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 P I + H ++ V + +V EY G L + G Sbjct 36 PRGLKIDENVAREIINHRSLRHPNIIRFKEVVLTPTHLAIVMEYAAGGELFDRI-CSAGR 94 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 QQL +SY + H ++ N LL +P +K+ D G Sbjct 95 FSEDESRYFFQQLICGVSYCHFMQICHRDLKLENTLLD-----GSPAPRLKICDFGYSKS 149 Query 766 AL---SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 +L + V ++APE L D W G TL + P Sbjct 150 SLLHSKPKSTVGTPAYIAPEVLSRREYD-GKMADVWSCGVTLYVMLVGAYPFEDPDDPKN 208 Query 823 KEH----FYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 Q+++PE L S+ P +R + R I ++ Sbjct 209 FRKTIGRIVSIQYKIPEYVHISQDCRQLLSRIFVANPAKRITIREIRNHPWFMKN 263 >sp|Q91819|AURAB_XENLA Aurora kinase A-B OS=Xenopus laevis OX=8355 GN=aurka-b PE=2 SV=3 Length=408 Score = 209 bits (531), Expect = 8e-58, Method: Composition-based stats. Identities = 62/312 (20%), Positives = 114/312 (37%), Gaps = 30/312 (10%) Query 851 YEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGK 910 + P + + + T+ + + R LG+G FG Sbjct 94 PNENRNPQQTSHSSTPNMEKKGSTDQGKTLAVPKEEGKKKQWCLEDFEIGRPLGKGKFGN 153 Query 911 VSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEIDILRTLYHEHIIKYKGCCED 968 V L + ++A+K L + ++E++I L H +I++ G D Sbjct 154 VYL----ARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHD 209 Query 969 QGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAAR 1027 + L+++Y P G L L + + L+ +Q+ E + Y H++ IHRD+ Sbjct 210 A--CRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLAEALLYCHSKKVIHRDIKPE 267 Query 1028 NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSF 1087 N+LL ++ +KI DFG + P R + + PE ++ D+WS Sbjct 268 NLLLGSNGELKIADFGWSVHAPSSR-----RTTLCGTLDYLPPEMIEGRMHDEKVDLWSL 322 Query 1088 GVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 GV YE L ++ Q T R++++ P E L Sbjct 323 GVLCYEFLVGKPPFETD-----------THQETYRRISKV-----EFQYPPYVSEEAKDL 366 Query 1148 MKNCWETEASFR 1159 + + + R Sbjct 367 VSKLLKHNPNHR 378 Score = 183 bits (464), Expect = 6e-49, Method: Composition-based stats. Identities = 56/301 (19%), Positives = 108/301 (36%), Gaps = 41/301 (14%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 ++ LG+G NVY R+R + + LKVL Sbjct 138 EDFEIGRPLGKGKFGNVYLA------------------------RERESKFILALKVLFK 173 Query 647 SHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 S + + + S + H ++ ++G ++ +Y G L L++ Sbjct 174 SQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDACRVYLILDYAPGGELFRELQK-C 232 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + +QLA AL Y +K ++H ++ N+LL G++ +K++D G Sbjct 233 TRFDDQRSALYIKQLAEALLYCHSKKVIHRDIKPENLLL-------GSNGELKIADFGWS 285 Query 764 LGALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + A S R + +L PE + G + +D W G E G+ P ++ + Sbjct 286 VHAPSSRRTTLCGTLDYLPPEMIEGRMH--DEKVDLWSLGVLCYEFLV-GKPPFETDTHQ 342 Query 822 EK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTV 880 E + + + P + L S+ L + P R + +L ++ Sbjct 343 ETYRRISKVEFQYPPYVSEEAKDLVSKLLKHNPNHRLPLKGVLEHPWIVKNSQQPKKKDE 402 Query 881 N 881 Sbjct 403 P 403 >sp|P34112|CDK1_DICDI Cyclin-dependent kinase 1 OS=Dictyostelium discoideum OX=44689 GN=cdk1 PE=2 SV=1 Length=296 Score = 205 bits (521), Expect = 8e-58, Method: Composition-based stats. Identities = 73/285 (26%), Positives = 120/285 (42%), Gaps = 26/285 (9%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 +K+ LGEG +GKV Y TG MVA+K ++ + S +EI +L+ + H Sbjct 10 YQKLEKLGEGTYGKV----YKAKEKATGRMVALKKIRLE-DDGVPSTALREISLLKEVPH 64 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLL-FAQQICEGMAYLH 1015 +++ Q L LV EY+ L+ Y+ QL+ + Q+ +G+AY H Sbjct 65 PNVVSLFDVLHCQN--RLYLVFEYLDQ-DLKKYMDSVPALCPQLIKSYLYQLLKGLAYSH 121 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRDL +N+L+D +K+ DFGLA+AV RV +++ APE L Sbjct 122 GHRILHRDLKPQNLLIDRQGALKLADFGLARAVSIP---VRVYTHEIVTLWYRAPEVLLG 178 Query 1076 YK-FYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM--TVLRLTEL 1127 K + D+WS G E+L + ++G + V +L E Sbjct 179 SKSYSVPVDMWSVGCIFGEMLNKKPLFSGDCEIDQIFRIFRVLGTPDDSIWPGVTKLPEY 238 Query 1128 LERGERLP------RPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + P +C L+ + E S R + + + Sbjct 239 VSTFPNWPGQPYNKIFPRCEPLALDLIAKMLQYEPSKRISAKEAL 283 Score = 155 bits (392), Expect = 1e-40, Method: Composition-based stats. Identities = 50/283 (18%), Positives = 91/283 (32%), Gaps = 38/283 (13%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 +L LG+GT VY+ + + G V LK + Sbjct 12 KLEKLGEGTYGKVYKAKEKATGRM------------------------VALKKIRLEDDG 47 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 + SL+ +V H ++ + V +V EY++ L ++ P Sbjct 48 VPSTALREISLLKEVPHPNVVSLFDVLHCQNRLYLVFEYLDQ-DLKKYMDSVPALCP-QL 105 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG----A 766 QL L+Y ++H ++ +N+L+ R G +KL+D G+ Sbjct 106 IKSYLYQLLKGLAYSHGHRILHRDLKPQNLLIDRQGA-------LKLADFGLARAVSIPV 158 Query 767 LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 + + + APE L G+ S S +D W G E+ + Sbjct 159 RVYTHEIVTLWYRAPEVLL-GSKSYSVPVDMWSVGCIFGEMLNKKPLFSGDCEIDQIFRI 217 Query 827 YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRL 869 ++ + P + L T+ + I L Sbjct 218 FRVLGTPDDSIWPGVTKLPEYVSTFPNWPGQPYNKIFPRCEPL 260 >sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens OX=9606 GN=RPS6KA1 PE=1 SV=2 Length=735 Score = 217 bits (553), Expect = 8e-58, Method: Composition-based stats. Identities = 66/259 (25%), Positives = 113/259 (44%), Gaps = 24/259 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961 LG+G FGKV L T +G + A+K LK + R K E DIL + H ++K Sbjct 68 LGQGSFGKVFLVR-KVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVK 126 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020 Q E L L+++++ G L L + + + ++ G+ +LH+ I Sbjct 127 LHYAF--QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGII 184 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 +RDL N+LLD + +K+ DFGL+K E ++ + V + APE + + Sbjct 185 YRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKKAYSFCGTVEYMAPEVVNRQGHSH 241 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ++D WS+GV ++E+LT Q K + + +L P Sbjct 242 SADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILK----------------AKLGMPQFL 285 Query 1141 PCEVYHLMKNCWETEASFR 1159 E L++ ++ + R Sbjct 286 STEAQSLLRALFKRNPANR 304 Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats. Identities = 62/272 (23%), Positives = 102/272 (38%), Gaps = 29/272 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHII 960 +G G + + + TN AVK + + +EI+IL H +II Sbjct 423 TIGVGSYSECKRCVHKATN----MEYAVKVIDKS-----KRDPSEEIEILLRYGQHPNII 473 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHY 1019 K +D K + LV E + G L D + R + I + + YLH+Q Sbjct 474 TLKDVYDDG--KHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGV 531 Query 1020 IHRDLAARNVL-LDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRDL N+L +D ++I DFG AK + + + APE LK Sbjct 532 VHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMT---PCYTANFVAPEVLKR 588 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + D+WS G+ LY +L + P+ E I +T + + G Sbjct 589 QGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEI------LTRIGSGKFTLSGGNW- 641 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + L+ + R T + ++ Sbjct 642 --NTVSETAKDLVSKMLHVDPHQRLTAKQVLQ 671 Score = 169 bits (427), Expect = 6e-42, Method: Composition-based stats. Identities = 54/282 (19%), Positives = 102/282 (36%), Gaps = 39/282 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + D L LGQG+ V+ + D L + Sbjct 55 EKADPSHFELLKVLGQGSFGKVFL----------VRKVTRPDSGHLY-----------AM 93 Query 642 KVLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 KVL + + +++ V+H + +H + ++ +++ G L L Sbjct 94 KVLKKATLKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRL 153 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 +E K +A +LA L +L + +++ ++ NILL G IKL+D Sbjct 154 SKEVMFTEEDVKFYLA-ELALGLDHLHSLGIIYRDLKPENILLDEEG-------HIKLTD 205 Query 760 PGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ A+ E++ + ++APE + +S S D W +G + E+ G P Sbjct 206 FGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS--ADWWSYGVLMFEML-TGSLPF 262 Query 816 QSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQR 856 Q + E + +P+ + +L P R Sbjct 263 QGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPANR 304 Score = 150 bits (379), Expect = 5e-36, Method: Composition-based stats. Identities = 50/277 (18%), Positives = 93/277 (34%), Gaps = 26/277 (9%) Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664 + + +G E + + + +KV+D S D + E ++ + Sbjct 410 KNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPS----EEIEILLR 465 Query 665 V-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723 H ++ + V G +VTE + G L + R++ V + + Sbjct 466 YGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKF-FSEREASFVLHTIGKTVE 524 Query 724 YLENKNLVHGNVCGRNIL-LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL--- 779 YL ++ +VH ++ NIL + G E +++ D G + + + Sbjct 525 YLHSQGVVHRDLKPSNILYVDESGNPE----CLRICDFGFAKQLRAENGLLMTPCYTANF 580 Query 780 -APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL---QSRSPSEKE-HFYQRQHRL- 833 APE L D W G L + G P S +P E + L Sbjct 581 VAPEVLK--RQGYDEGCDIWSLGILLYTMLA-GYTPFANGPSDTPEEILTRIGSGKFTLS 637 Query 834 ---PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 L S+ L +P QR + + +L+ Sbjct 638 GGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPW 674 >sp|O64629|AUR3_ARATH Serine/threonine-protein kinase Aurora-3 OS=Arabidopsis thaliana OX=3702 GN=AUR3 PE=2 SV=1 Length=288 Score = 204 bits (520), Expect = 8e-58, Method: Composition-based stats. Identities = 61/280 (22%), Positives = 116/280 (41%), Gaps = 29/280 (10%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS--GWKQEI 948 + + R LG+G FG+V L + +VA+K + + +++ ++E+ Sbjct 16 QWSLADFEIGRPLGKGKFGRVYL----AREAKSKYIVALKVIFKEQIEKYKIHHQLRREM 71 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQI 1007 +I +L H +I++ G D + + L++EY G L L ++ + Q + + Sbjct 72 EIQTSLRHPNILRLFGWFHDN--ERIFLILEYAHGGELYGVLKQNGHLTEQQAATYIASL 129 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + +AY H + IHRD+ N+LLD++ +KI DFG + R+ + + Sbjct 130 SQALAYCHGKCVIHRDIKPENLLLDHEGRLKIADFGWSVQ------SSNKRKTMCGTLDY 183 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE ++ YA D W+ G+ YE L ++ K + Sbjct 184 LAPEMVENRDHDYAVDNWTLGILCYEFLYGNPPFEAESQKDT--------------FKRI 229 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L+ P E +L+ + S R + E ++ Sbjct 230 LKIDLSFPLTPNVSEEAKNLISQLLVKDPSKRLSIEKIMQ 269 Score = 176 bits (446), Expect = 6e-48, Method: Composition-based stats. Identities = 56/298 (19%), Positives = 103/298 (35%), Gaps = 42/298 (14%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + LG+G VY R+ + V LKV+ Sbjct 21 DFEIGRPLGKGKFGRVYLA------------------------REAKSKYIVALKVIFKE 56 Query 648 HHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + I + + + H ++ + G ++ EY G L L++ G Sbjct 57 QIEKYKIHHQLRREMEIQTSLRHPNILRLFGWFHDNERIFLILEYAHGGELYGVLKQN-G 115 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG- 763 H+ L+ AL+Y K ++H ++ N+LL G +K++D G Sbjct 116 HLTEQQAATYIASLSQALAYCHGKCVIHRDIKPENLLLDHEGR-------LKIADFGWSV 168 Query 764 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 + R+ + +LAPE + + A+D W G E G P ++ S + Sbjct 169 QSSNKRKTMCGTLDYLAPEMVENRDHDY--AVDNWTLGILCYE-FLYGNPPFEAESQKDT 225 Query 824 EHFYQR---QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVL 878 + L + L SQ L +P++R S I++ ++ + V Sbjct 226 FKRILKIDLSFPLTPNVSEEAKNLISQLLVKDPSKRLSIEKIMQHPWIVKNADPKGVC 283 >sp|Q63531|KS6A1_RAT Ribosomal protein S6 kinase alpha-1 OS=Rattus norvegicus OX=10116 GN=Rps6ka1 PE=1 SV=1 Length=735 Score = 217 bits (553), Expect = 8e-58, Method: Composition-based stats. Identities = 66/259 (25%), Positives = 112/259 (43%), Gaps = 24/259 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961 LG+G FGKV L T G + A+K LK + R K E DIL + H ++K Sbjct 68 LGQGSFGKVFLVR-KVTRPDNGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVK 126 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020 Q E L L+++++ G L L + + + ++ G+ +LH+ I Sbjct 127 LHYAF--QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGII 184 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 +RDL N+LLD + +K+ DFGL+K E ++ + V + APE + + Sbjct 185 YRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKKAYSFCGTVEYMAPEVVNRQGHTH 241 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ++D WS+GV ++E+LT Q K + + +L P Sbjct 242 SADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILK----------------AKLGMPQFL 285 Query 1141 PCEVYHLMKNCWETEASFR 1159 E L++ ++ + R Sbjct 286 STEAQSLLRALFKRNPANR 304 Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 63/272 (23%), Positives = 101/272 (37%), Gaps = 29/272 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHEHII 960 +G G + + TN AVK + + +EI+IL H +II Sbjct 423 TIGVGSYSVCKRCVHKATN----MEYAVKVIDKS-----KRDPSEEIEILLRYGQHPNII 473 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLLLFAQQICEGMAYLHAQHY 1019 K +D K + LV E + G L D + R + I + + YLH+Q Sbjct 474 TLKDVYDDS--KHVYLVTELMRGGELLDKILRQKFFSEREASFVLYTISKTVEYLHSQGV 531 Query 1020 IHRDLAARNVL-LDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRDL N+L +D ++I DFG AK + + + APE LK Sbjct 532 VHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMT---PCYTANFVAPEVLKR 588 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + D+WS GV LY +L + P+ E I +T + + G Sbjct 589 QGYDEGCDIWSLGVLLYTMLAGYTPFANGPSDTPEEI------LTRISSGKFTLSGGNW- 641 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + L+ + R T + ++ Sbjct 642 --NTVSETAKDLVSKMLHVDPHQRLTAKQVLQ 671 Score = 169 bits (429), Expect = 4e-42, Method: Composition-based stats. Identities = 53/282 (19%), Positives = 102/282 (36%), Gaps = 39/282 (14%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 + D L LGQG+ V+ + D L + Sbjct 55 EKADPSHFELLKVLGQGSFGKVFL----------VRKVTRPDNGHLY-----------AM 93 Query 642 KVLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWL 699 KVL + + +++ V+H + +H + ++ +++ G L L Sbjct 94 KVLKKATLKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRL 153 Query 700 RRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSD 759 +E K +A +LA L +L + +++ ++ NILL G IKL+D Sbjct 154 SKEVMFTEEDVKFYLA-ELALGLDHLHSLGIIYRDLKPENILLDEEG-------HIKLTD 205 Query 760 PGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ A+ E++ + ++APE + ++ S D W +G + E+ G P Sbjct 206 FGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHS--ADWWSYGVLMFEML-TGSLPF 262 Query 816 QSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQR 856 Q + E + +P+ + +L P R Sbjct 263 QGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPANR 304 Score = 150 bits (380), Expect = 5e-36, Method: Composition-based stats. Identities = 52/293 (18%), Positives = 97/293 (33%), Gaps = 26/293 (9%) Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664 + + +G E + + + +KV+D S D + E ++ + Sbjct 410 KNLVFSDGYIVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKSKRDPS----EEIEILLR 465 Query 665 V-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723 H ++ + V +VTE + G L + R++ V ++ + Sbjct 466 YGQHPNIITLKDVYDDSKHVYLVTELMRGGELLDKILRQKF-FSEREASFVLYTISKTVE 524 Query 724 YLENKNLVHGNVCGRNIL-LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL--- 779 YL ++ +VH ++ NIL + G E +++ D G + + + Sbjct 525 YLHSQGVVHRDLKPSNILYVDESGNPE----CLRICDFGFAKQLRAENGLLMTPCYTANF 580 Query 780 -APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL---QSRSPSEKE-HFYQRQHRL- 833 APE L D W G L + G P S +P E + L Sbjct 581 VAPEVLK--RQGYDEGCDIWSLGVLLYTMLA-GYTPFANGPSDTPEEILTRISSGKFTLS 637 Query 834 ---PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 L S+ L +P QR + + +L+ Q L + D Sbjct 638 GGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLPQSQLSHQD 690 >sp|Q39025|MPK5_ARATH Mitogen-activated protein kinase 5 OS=Arabidopsis thaliana OX=3702 GN=MPK5 PE=2 SV=2 Length=376 Score = 207 bits (528), Expect = 8e-58, Method: Composition-based stats. Identities = 73/323 (23%), Positives = 123/323 (38%), Gaps = 34/323 (11%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KA 934 + + +Y+ IR +G G +G V + T E +A+K + KA Sbjct 22 HGGRYFQYNVYGNLFEVSNKYVPPIRPIGRGAYGFVCA----AVDSETHEEIAIKKIGKA 77 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSL---QLVMEYVPLGSLRDYLP 991 +EI +LR L HE+++ K ++ +V E + L + Sbjct 78 FDNKVDAKRTLREIKLLRHLEHENVVVIKDIIRPPKKEDFVDVYIVFELMD-TDLHQIIR 136 Query 992 -RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 S+ F QI G+ Y+H+ + +HRDL N+LL+++ +KI DFGLA+ E Sbjct 137 SNQSLNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNSNCDLKITDFGLARTTSE 196 Query 1051 GHEYYRVREDGDSPVFWYAPE-CLKEYKFYYASDVWSFGVTLYELLTHCDSSQ------- 1102 + ++ APE L ++ A DVWS G E++T Sbjct 197 TEY----MTEYVVTRWYRAPELLLNSSEYTSAIDVWSVGCIFAEIMTREPLFPGKDYVHQ 252 Query 1103 ---------SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWE 1153 SP LE + A + V L + + P + L++ Sbjct 253 LKLITELIGSPDGASLEFLRSANARKYVKELPKFPRQNFSARFPSMNSTAI-DLLEKMLV 311 Query 1154 TEASFRPTFENLI--PILKTVHE 1174 + R T E + P L +H+ Sbjct 312 FDPVKRITVEEALCYPYLSALHD 334 Score = 131 bits (329), Expect = 2e-31, Method: Composition-based stats. Identities = 38/238 (16%), Positives = 80/238 (34%), Gaps = 44/238 (18%) Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 V K + + +G+G V D + +K Sbjct 37 EVSNKYVPPIRPIGRGAYGFVC------------------------AAVDSETHEEIAIK 72 Query 643 VLDPSHHDIALAF--YETASLMSQVSHTHLAFVHGVCVRGPE-----NIMVTEYVEHGPL 695 + + + A L+ + H ++ + + + +V E ++ L Sbjct 73 KIGKAFDNKVDAKRTLREIKLLRHLEHENVVVIKDIIRPPKKEDFVDVYIVFELMD-TDL 131 Query 696 DVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFI 755 +R + + Q+ L Y+ + N++H ++ N+LL ++ + Sbjct 132 HQIIRSNQ-SLNDDHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLN-------SNCDL 183 Query 756 KLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFD 810 K++D G+ E E V + APE L ++ ++A+D W G EI Sbjct 184 KITDFGLARTTSETEYMTEYVVTRWYRAPELLLN-SSEYTSAIDVWSVGCIFAEIMTR 240 >sp|Q62799|ERBB3_RAT Receptor tyrosine-protein kinase erbB-3 OS=Rattus norvegicus OX=10116 GN=Erbb3 PE=1 SV=3 Length=1339 Score = 223 bits (567), Expect = 8e-58, Method: Composition-based stats. Identities = 89/272 (33%), Positives = 139/272 (51%), Gaps = 20/272 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 LG G FG V + P + V +K ++ G Q + + +L H HI++ Sbjct 713 LGSGVFGTVHKGIWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAVGSLDHAHIVRL 772 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHYI 1020 G C SLQLV +Y+PLGSL D++ +H ++G LL + QI +GM YL + Sbjct 773 LGLC---PGSSLQLVTQYLPLGSLLDHVKQHRETLGPQLLLNWGVQIAKGMYYLEEHSMV 829 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 HRDLA RNV+L + V++ DFG+A +P + + + +P+ W A E + K+ + Sbjct 830 HRDLALRNVMLKSPSQVQVADFGVADLLPP-DDKQLLHSEAKTPIKWMALESIHFGKYTH 888 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 SDVWS+GVT++EL+T + + + +LLE+GERL +P C Sbjct 889 QSDVWSYGVTVWELMTFG--------------AEPYAGLRLAEIPDLLEKGERLAQPQIC 934 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIPILKTV 1172 +VY +M CW + + RPTF+ L + Sbjct 935 TIDVYMVMVKCWMIDENIRPTFKELANEFTRM 966 Score = 199 bits (505), Expect = 2e-50, Method: Composition-based stats. Identities = 62/301 (21%), Positives = 118/301 (39%), Gaps = 39/301 (13%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 + E+ +L LG G V++G EG ++ V +KV+ Sbjct 703 KETELRKLKVLGSGVFGTVHKGIWIPEGESI--------------------KIPVCIKVI 742 Query 645 -DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 D S A + + + H H+ + G+C G +VT+Y+ G L +++ R Sbjct 743 EDKSGRQSFQAVTDHMLAVGSLDHAHIVRLLGLCP-GSSLQLVTQYLPLGSLLDHVKQHR 801 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + + Q+A + YLE ++VH ++ RN++L + ++++D GV Sbjct 802 ETLGPQLLLNWGVQIAKGMYYLEEHSMVHRDLALRNVML-------KSPSQVQVADFGVA 854 Query 764 LGALSRE------ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + E I W+A E + G + D W +G T+ E+ G P Sbjct 855 DLLPPDDKQLLHSEAKTPIKWMALESIHFG--KYTHQSDVWSYGVTVWELMTFGAEPYAG 912 Query 818 RSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 +E ++ RL P+ + + +C + RP+F+ + + TR+ Sbjct 913 LRLAEIPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPR 972 Query 876 D 876 Sbjct 973 Y 973 >sp|Q9C098|DCLK3_HUMAN Serine/threonine-protein kinase DCLK3 OS=Homo sapiens OX=9606 GN=DCLK3 PE=1 SV=2 Length=648 Score = 215 bits (548), Expect = 8e-58, Method: Composition-based stats. Identities = 69/277 (25%), Positives = 108/277 (39%), Gaps = 27/277 (10%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 + + R +G+G+F V + + T + A+K + EI I+++L Sbjct 355 HYETGRVIGDGNFAVVK----ECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLS 410 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYL 1014 H +I+K E E + L++EYV G L D + L +C+ + ++ Sbjct 411 HPNIVKLHEVYETDME--IYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHM 468 Query 1015 HAQHYIHRDLAARNVLL----DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAP 1070 H + +HRDL N+L+ D +K+ DFGLAK V R + AP Sbjct 469 HDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHV------VRPIFTVCGTPTYVAP 522 Query 1071 ECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 E L E + D+W+ GV LY LL +SP EL I Q E L Sbjct 523 EILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGH-----FEFL-- 575 Query 1131 GERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 P D L+ + R T ++ Sbjct 576 ---PPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQ 609 Score = 161 bits (407), Expect = 1e-39, Method: Composition-based stats. Identities = 62/324 (19%), Positives = 110/324 (34%), Gaps = 45/324 (14%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 P+ N R + PR + + + + +G G V E Sbjct 325 PKTRPEENKPE-RPSGRKPRPMGIIAANVEK----HYETGRVIGDGNFAVVKE------- 372 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYE-TASLMSQVSHTHLA 671 R R +K++D S + ++ +SH ++ Sbjct 373 -----------------CRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIV 415 Query 672 FVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLV 731 +H V E ++ EYV+ G L + E P ++ L AL ++ +K++V Sbjct 416 KLHEVYETDMEIYLILEYVQGGDLFDAII-ESVKFPEPDAALMIMDLCKALVHMHDKSIV 474 Query 732 HGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR-EERVERIPWLAPECLPGGANS 790 H ++ N+L+ R E S +KL+D G+ + ++APE L Sbjct 475 HRDLKPENLLVQRN---EDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSE--KG 529 Query 791 LSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQ-------HRLPEPSCPQLAT 843 +D W G L I G P +S + E F Q + Sbjct 530 YGLEVDMWAAGVILY-ILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKD 588 Query 844 LTSQCLTYEPTQRPSFRTILRDLT 867 L S+ L +P +R + +L+ Sbjct 589 LVSRLLVVDPKKRYTAHQVLQHPW 612 >sp|Q6IP76|AKT2B_XENLA RAC-beta serine/threonine-protein kinase B OS=Xenopus laevis OX=8355 GN=akt2-b PE=2 SV=1 Length=485 Score = 211 bits (537), Expect = 8e-58, Method: Composition-based stats. Identities = 66/260 (25%), Positives = 98/260 (38%), Gaps = 28/260 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960 LG+G FGKV L TG A+K L+ + + E +L+ H + Sbjct 162 LGKGTFGKVILV----REKATGLYYAMKILRKEVIIAKDEVAHTLTESRVLQNTKHPFLT 217 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019 K Q L VMEY G L +L R + + +I + YLH+++ Sbjct 218 GLKYAF--QTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRNV 275 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 ++RD+ N++LD D VKI DFGL K EG + APE L++ + Sbjct 276 VYRDIKLENLMLDKDGHVKITDFGLCK---EGITDGATMRTFCGTPEYLAPEVLEDNDYG 332 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 A D W GV +YE++ Q +L R PR Sbjct 333 RAVDWWGLGVVMYEMMCGRLPF--------------YNQDHERLFELILMEETRFPR--T 376 Query 1140 CPCEVYHLMKNCWETEASFR 1159 E L+ + + R Sbjct 377 LSPEAKSLLAGLLKKDPKQR 396 Score = 168 bits (425), Expect = 4e-43, Method: Composition-based stats. Identities = 57/283 (20%), Positives = 97/283 (34%), Gaps = 43/283 (15%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 +V + L LG+GT V + R++ L + Sbjct 149 PKVTMNDFDYLKLLGKGTFGKV------------------------ILVREKATGLYYAM 184 Query 642 KVLDPSHHDIALAF---YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 K+L + ++ H L + V EY G L Sbjct 185 KILRKEVIIAKDEVAHTLTESRVLQNTKHPFLTGLKYAFQTSDRLCFVMEYANGGELFFH 244 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 L RER ++ SAL YL ++N+V+ ++ N++L + G +K++ Sbjct 245 LSRER-VFTEDRARFYGAEIVSALEYLHSRNVVYRDIKLENLMLDKDG-------HVKIT 296 Query 759 DPGVGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 D G+ ++ +LAPE L N A+D WG G + E+ G P Sbjct 297 DFGLCKEGITDGATMRTFCGTPEYLAPEVLED--NDYGRAVDWWGLGVVMYEMMC-GRLP 353 Query 815 LQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 ++ + R P P+ +L + L +P QR Sbjct 354 FYNQDHERLFELILMEETRFPRTLSPEAKSLLAGLLKKDPKQR 396 >sp|Q8TDC3|BRSK1_HUMAN Serine/threonine-protein kinase BRSK1 OS=Homo sapiens OX=9606 GN=BRSK1 PE=1 SV=2 Length=778 Score = 218 bits (554), Expect = 9e-58, Method: Composition-based stats. Identities = 71/279 (25%), Positives = 117/279 (42%), Gaps = 29/279 (10%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDI 950 + + + LG+G G V L + TG+ VA+K + + ++EI I Sbjct 29 QYVGPYRLEKTLGKGQTGLVKLG----VHCITGQKVAIKIVNREKLSESVLMKVEREIAI 84 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICE 1009 L+ + H H++K E++ K L LV+E+V G L DYL + + + F +QI Sbjct 85 LKLIEHPHVLKLHDVYENK--KYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVS 142 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + + H+ HRDL N+LLD ++I DFG+A + E + Sbjct 143 ALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASL----QVGDSLLETSCGSPHYAC 198 Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE +K K+ +D+WS GV L+ LL + +L E + Sbjct 199 PEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDD---------------NLRQLLEKV 243 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 +RG P P + L++ E E R + E + Sbjct 244 KRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQK 281 Score = 169 bits (428), Expect = 7e-42, Method: Composition-based stats. Identities = 54/329 (16%), Positives = 101/329 (31%), Gaps = 44/329 (13%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647 LG+G V G + G +V +K+++ Sbjct 35 RLEKTLGKGQTGLVKLGVHCITGQ------------------------KVAIKIVNREKL 70 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 + + +++ + H H+ +H V +V E+V G L +L ++G + Sbjct 71 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYL-VKKGRLT 129 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 +Q+ SAL + + ++ H ++ N+LL I+++D G+ + Sbjct 130 PKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKN-------NIRIADFGMASLQV 182 Query 768 SR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 E + PE + G D W G L + G P + + Sbjct 183 GDSLLETSCGSPHYACPEVIKGEKYD-GRRADMWSCGVILFALLV-GALPFDDDNLRQLL 240 Query 825 HFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 +R +P P +L + EP +R S I + L + D Sbjct 241 EKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAP 300 Query 884 SPASDPTVFHKRYLKKIRDLGE----GHF 908 L G F Sbjct 301 GRRVAMRSLPSNGELDPDVLESMASLGCF 329 >sp|O75011|NAK1_SCHPO Serine/threonine-protein kinase nak1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=nak1 PE=1 SV=1 Length=652 Score = 215 bits (548), Expect = 9e-58, Method: Composition-based stats. Identities = 65/270 (24%), Positives = 113/270 (42%), Gaps = 30/270 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH---EHI 959 +G G +G V Y + T E VA+K L D S ++E+ +L L E+I Sbjct 16 VGRGSYGAV----YRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQSDVENI 71 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 IKY G +L ++M+Y GS+R + I + L ++ + + ++H Sbjct 72 IKYHGSYLVGT--NLWIIMDYCHGGSVRTLMEAGPISEPCISLILRETLQALKFIHHAGI 129 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK-F 1078 IHRD+ A N+L+ VK+ DFG+A + R R +W APE +++ + + Sbjct 130 IHRDIKAANILVSMSGNVKLCDFGVAAELNINR---RKRITFIGTPYWMAPEVIRDGQEY 186 Query 1079 YYASDVWSFGVTLYELLTHCDS-SQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 +D+WS G+T YE+ T ++ P + + LI + L Sbjct 187 NVMADIWSLGITAYEIATGSPPHAKEDPFRAVYLIAHTAPPRLNGNFSAL---------- 236 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + +C + R L+ Sbjct 237 ------LKEFIASCLQDVPQRRLDSSELLK 260 Score = 177 bits (448), Expect = 5e-45, Method: Composition-based stats. Identities = 56/311 (18%), Positives = 108/311 (35%), Gaps = 45/311 (14%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD-PSH 648 T+L +G+G+ VY G + + V +K+L+ + Sbjct 11 TKLELVGRGSYGAVYRGICNL------------------------TKETVAIKILNLDTD 46 Query 649 HDIALAFYETASLMSQVSH---THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 D + +++S++ ++ HG + G ++ +Y G + + E G Sbjct 47 EDEVSDIQKEVAVLSELKQSDVENIIKYHGSYLVGTNLWIIMDYCHGGSVRTLM--EAGP 104 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG-- 763 + ++ ++ AL ++ + ++H ++ NIL++ S +KL D GV Sbjct 105 ISEPCISLILRETLQALKFIHHAGIIHRDIKAANILVS-------MSGNVKLCDFGVAAE 157 Query 764 --LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + R + W+APE + G + D W G T EI G P P Sbjct 158 LNINRRKRITFIGTPYWMAPEVIRDG-QEYNVMADIWSLGITAYEIA-TGSPPHAKEDPF 215 Query 822 EKEHF--YQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 + + RL L + CL P +R +L+ Q ++ Sbjct 216 RAVYLIAHTAPPRLNGNFSALLKEFIASCLQDVPQRRLDSSELLKSKFIKQYSRMSISEL 275 Query 880 VNPDSPASDPT 890 N Sbjct 276 TNVVKRYDTWQ 286 >sp|Q07176|MMK1_MEDSA Mitogen-activated protein kinase homolog MMK1 OS=Medicago sativa OX=3879 GN=MMK1 PE=1 SV=1 Length=387 Score = 207 bits (528), Expect = 1e-57, Method: Composition-based stats. Identities = 72/321 (22%), Positives = 118/321 (37%), Gaps = 31/321 (10%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KA 934 + + +Y I +G+G +G V N T E VAVK + A Sbjct 34 HGGRFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVCSAH----NSETNEHVAVKKIANA 89 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEK---SLQLVMEYVPLGSLRDYLP 991 +EI +LR + HE+++ + + + + E + L + Sbjct 90 FDNKIDAKRTLREIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMD-TDLHQIIR 148 Query 992 -RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPE 1050 ++ F QI G+ Y+H+ + +HRDL N+LL+ + +KI DFGLA+ E Sbjct 149 SNQALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSE 208 Query 1051 GHEYYRVREDGDSPVFWYAPE-CLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-----SP 1104 + ++ APE L + A DVWS G EL+ Sbjct 209 TD----FMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQ 264 Query 1105 PTKFLELIGIAQGQ------MTVLRLTELLERGERLPRPDKCP---CEVYHLMKNCWETE 1155 +ELIG R L R +K P E L++ + Sbjct 265 LRLLMELIGTPSEDDLGFLNENAKRYIRQLPPYRRQSFQEKFPHVHPEAIDLVEKMLTFD 324 Query 1156 ASFRPTFENLI--PILKTVHE 1174 R T E+ + P L ++H+ Sbjct 325 PRKRITVEDALAHPYLTSLHD 345 Score = 126 bits (317), Expect = 7e-30, Method: Composition-based stats. Identities = 32/219 (15%), Positives = 75/219 (34%), Gaps = 22/219 (10%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF--YE 657 N++E + + + + V +K + + + A Sbjct 44 FGNIFE--VTAKYKPPIMPIGKGAYGIVCSAHNSETNEHVAVKKIANAFDNKIDAKRTLR 101 Query 658 TASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 L+ + H ++ + + + + E ++ L +R + + Sbjct 102 EIKLLRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMD-TDLHQIIRSNQA-LSEEHCQ 159 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE-- 770 Q+ L Y+ + N++H ++ N+LL + +K+ D G+ + Sbjct 160 YFLYQILRGLKYIHSANVLHRDLKPSNLLLN-------ANCDLKICDFGLARVTSETDFM 212 Query 771 -ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 E V + APE L ++ + A+D W G +E+ Sbjct 213 TEYVVTRWYRAPELLLN-SSDYTAAIDVWSVGCIFMELM 250 >sp|Q38868|CDPK9_ARATH Calcium-dependent protein kinase 9 OS=Arabidopsis thaliana OX=3702 GN=CPK9 PE=1 SV=1 Length=541 Score = 212 bits (540), Expect = 1e-57, Method: Composition-based stats. Identities = 78/357 (22%), Positives = 131/357 (37%), Gaps = 30/357 (8%) Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 P + + + P T ++ L+ Sbjct 12 MKPQQNGNTTRSVEVGVTNQDPPSYTPQARTTQQPEKPGSVNSQPPPWRAAAAAPGLSPK 71 Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KAD 935 T +S + K + ++LG G FG L T + TG+ A K++ K Sbjct 72 TTTKSNSILENAFEDVKLFYTLGKELGRGQFGVTYLC----TENSTGKKYACKSISKKKL 127 Query 936 CGPQHRSGWKQEIDILRTLYH-EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRH 993 + ++EI I++ L +I+++KG ED EK++ LVME G L D + + Sbjct 128 VTKADKDDMRREIQIMQHLSGQPNIVEFKGAYED--EKAVNLVMELCAGGELFDRIIAKG 185 Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPE 1050 +QI + H +HRDL N LL D L+K DFGL+ + E Sbjct 186 HYTERAAASVCRQIVNVVKICHFMGVLHRDLKPENFLLSSKDEKALIKATDFGLSVFIEE 245 Query 1051 GHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE 1110 G Y D ++ APE L+ ++ D+WS G+ LY LL+ + K + Sbjct 246 GKVY----RDIVGSAYYVAPEVLR-RRYGKEVDIWSAGIILYILLSGVPPFWAETEKGI- 299 Query 1111 LIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 I +G + E P P L++ + R + +++ Sbjct 300 FDAILEGHIDF----------ESQPWP-SISSSAKDLVRRMLTADPKRRISAADVLQ 345 Score = 137 bits (345), Expect = 2e-32, Method: Composition-based stats. Identities = 51/311 (16%), Positives = 96/311 (31%), Gaps = 40/311 (13%) Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 + + ++ ++ + +F V T LG+G Y +G K + Sbjct 69 SPKTTTKSNSILENAFEDVKLF-YTLGKELGRGQFGVTY--LCTENSTGKKYACKSISKK 125 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS-HTHLAFVHGVCVRGPENI 684 LV D+ +M +S ++ G Sbjct 126 KLVTKADK-------------------DDMRREIQIMQHLSGQPNIVEFKGAYEDEKAVN 166 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 +V E G L + +GH V +Q+ + + ++H ++ N LL+ Sbjct 167 LVMELCAGGELFDRIIA-KGHYTERAAASVCRQIVNVVKICHFMGVLHRDLKPENFLLSS 225 Query 745 LGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFG 801 + IK +D G+ + + + V ++APE L +D W G Sbjct 226 ----KDEKALIKATDFGLSVFIEEGKVYRDIVGSAYYVAPEVLR---RRYGKEVDIWSAG 278 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQH-----RLPEPSCPQLATLTSQCLTYEPTQR 856 L I G P + + H + L + LT +P +R Sbjct 279 IILY-ILLSGVPPFWAETEKGIFDAILEGHIDFESQPWPSISSSAKDLVRRMLTADPKRR 337 Query 857 PSFRTILRDLT 867 S +L+ Sbjct 338 ISAADVLQHPW 348 >sp|Q9P7I2|KCC1_SCHPO Calcium/calmodulin-dependent protein kinase type I OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=cmk1 PE=1 SV=1 Length=335 Score = 206 bits (523), Expect = 1e-57, Method: Composition-based stats. Identities = 69/298 (23%), Positives = 108/298 (36%), Gaps = 28/298 (9%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 + R LG G + V + + T +M A K + + + K EI IL+ Sbjct 28 PCKYRVGRVLGGGTYATVR----EAVHIETNKMYAAKIMNKKMMEKKQDFVKNEIAILKR 83 Query 954 LY--HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICEG 1010 + H +I+ E +L L+ E G L D + + S A + Sbjct 84 VSYEHPNILHLVDFFE--TVNNLYLITELATGGELFDRICAKGSFYEADAAALMRTTTSA 141 Query 1011 MAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 + YLH +HRDL N+L D + + I DFGL+ E +YY + +P + Sbjct 142 VKYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSH-FYEDSQYYMLMTACGTPE-Y 199 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE + + D+W+ GV Y LL+ P Q+ V+ Sbjct 200 MAPEVFRRTGYGKPVDMWAIGVITYFLLSGYTPFARP------------SQVEVIEAILA 247 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVHEKYQGQAPSV 1183 E P +K C E + S R T + + P L P+V Sbjct 248 NEYTFNDPCWSGISETAKDFIKKCLENDPSKRLTAADALKHPFLSEKRPATSNLLPNV 305 Score = 145 bits (367), Expect = 7e-37, Method: Composition-based stats. Identities = 42/282 (15%), Positives = 83/282 (29%), Gaps = 45/282 (16%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + LG GT V E K+++ Sbjct 30 KYRVGRVLGGGTYATVREAVHIETNKMY------------------------AAKIMNKK 65 Query 648 HHDIALAF-YETASLMSQVS--HTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 + F +++ +VS H ++ + ++TE G L + +G Sbjct 66 MMEKKQDFVKNEIAILKRVSYEHPNILHLVDFFETVNNLYLITELATGGELFDRI-CAKG 124 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 A + + SA+ YL + +VH ++ N+L ++ + + ++D G+ Sbjct 125 SFYEADAAALMRTTTSAVKYLHDNGIVHRDLKPENLL----YRSKDPNSDLLIADFGLSH 180 Query 765 GALSREERV-----ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 + + ++APE +D W G + G P S Sbjct 181 FYEDSQYYMLMTACGTPEYMAPEVFR--RTGYGKPVDMWAIGVITYFLLS-GYTPFARPS 237 Query 820 PSEKEHF-----YQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 E Y +CL +P++R Sbjct 238 QVEVIEAILANEYTFNDPCWSGISETAKDFIKKCLENDPSKR 279 >sp|P24923|CDC21_MEDSA Cell division control protein 2 homolog 1 (Fragment) OS=Medicago sativa OX=3879 GN=CDC2A PE=2 SV=1 Length=291 Score = 204 bits (519), Expect = 1e-57, Method: Composition-based stats. Identities = 71/287 (25%), Positives = 124/287 (43%), Gaps = 33/287 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHII 960 +GEG +G V Y + T E +A+K ++ + + S +EI +L+ + H +I+ Sbjct 6 KIGEGTYGVV----YKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHRNIV 61 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI---GLAQLLLFAQQICEGMAYLHAQ 1017 + + +K L LV EY+ L L+ ++ Q+ +F Q+ G+AY H+ Sbjct 62 RLQDVV--HSDKRLYLVFEYLDL-DLKKHMDSSPEFIKDPRQVKMFLYQMLCGIAYCHSH 118 Query 1018 HYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 +HRDL +N+L+D +K+ DFGLA+A R +++ APE L Sbjct 119 RVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIP---VRTFTHEVVTLWYRAPEILLGS 175 Query 1077 K-FYYASDVWSFGVTLYEL-----LTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLER 1130 + + DVWS G E+ L+ DS K ++G T +T L + Sbjct 176 RHYSTPVDVWSVGCIFAEMANRRPLSPGDSEIDELFKIFRILGTPNED-TWPGVTSLPDF 234 Query 1131 GERLPR----------PDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 PR P+ P + L+ + + + R T + + Sbjct 235 KSTFPRWPSKDLATVVPNLEPAGL-DLLNSMLCLDPTKRITARSAVE 280 Score = 160 bits (404), Expect = 2e-42, Method: Composition-based stats. Identities = 45/262 (17%), Positives = 92/262 (35%), Gaps = 39/262 (15%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--VLDPS 647 + +G+GT VY+ RDR + LK L+ Sbjct 2 ENVEKIGEGTYGVVYKA------------------------RDRVTNETIALKKIRLEQE 37 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 + SL+ ++ H ++ + V +V EY++ L + + Sbjct 38 DEGVPSTAIREISLLKEMQHRNIVRLQDVVHSDKRLYLVFEYLDL-DLKKHMDSSPEFIK 96 Query 708 MAWKMVV-AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG- 765 ++ + Q+ ++Y + ++H ++ +N+L+ R + +KL+D G+ Sbjct 97 DPRQVKMFLYQMLCGIAYCHSHRVLHRDLKPQNLLIDRR------TNSLKLADFGLARAF 150 Query 766 ---ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + V + + APE L G+ ST +D W G E+ E Sbjct 151 GIPVRTFTHEVVTLWYRAPEILL-GSRHYSTPVDVWSVGCIFAEMANRRPLSPGDSEIDE 209 Query 823 KEHFYQRQHRLPEPSCPQLATL 844 ++ E + P + +L Sbjct 210 LFKIFRILGTPNEDTWPGVTSL 231 >sp|Q5QN75|M2K1_ORYSJ Mitogen-activated protein kinase kinase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=MKK1 PE=1 SV=1 Length=355 Score = 206 bits (525), Expect = 1e-57, Method: Composition-based stats. Identities = 73/320 (23%), Positives = 133/320 (42%), Gaps = 23/320 (7%) Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTN 920 + + LQ + + + L+ I+ +G+G G V L + Sbjct 35 ELRLNQRGLQLISEETADEPQSTNLKVEDVQLSMDDLEMIQVIGKGSGGIVQLV----RH 90 Query 921 DGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEY 980 G + A+K ++ + R QE+ I + + HI+ G + LV+EY Sbjct 91 KWVGTLYALKGIQMNIQEAVRKQIVQELKINQATQNAHIVLCHQSFYHNG--VIYLVLEY 148 Query 981 VPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHA-QHYIHRDLAARNVLLDNDRLVK 1038 + GSL D + + +I L + +Q+ EG+ YLH +H IHRD+ N+L++ VK Sbjct 149 MDRGSLADIIKQVKTILEPYLAVLCKQVLEGLLYLHHERHVIHRDIKPSNLLVNRKGEVK 208 Query 1039 IGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHC 1098 I DFG++ + R+ + APE + + Y SD+WS G+ + E C Sbjct 209 ITDFGVSAVLASSMGQ---RDTFVGTYNYMAPERISGSSYDYKSDIWSLGLVILE----C 261 Query 1099 DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP-DKCPCEVYHLMKNCWETEAS 1157 + P + +G ++ L E + P D+ E + +C + + + Sbjct 262 AIGRFPY-----IPSEGEGWLSFYELLEAIVDQPPPSAPADQFSPEFCAFISSCIQKDPA 316 Query 1158 FRPTFENLI--PILKTVHEK 1175 R + L+ P +K +K Sbjct 317 ERMSASELLNHPFIKKFEDK 336 Score = 166 bits (419), Expect = 2e-43, Method: Composition-based stats. Identities = 53/320 (17%), Positives = 114/320 (36%), Gaps = 49/320 (15%) Query 562 IIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKM 621 +I P++ NL + ++ ++ + +G+G+ V R + G+ +G Sbjct 45 LISEETADEPQSTNLK-VEDVQLSMDDLEMIQVIGKGSGGIVQLVRHKWVGTLYALKGIQ 103 Query 622 DDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP 681 + ++ + + + + H+ H Sbjct 104 MN-------------IQEAV----------RKQIVQELKINQATQNAHIVLCHQSFYHNG 140 Query 682 ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYL-ENKNLVHGNVCGRNI 740 +V EY++ G L +++ + + + V+ +Q+ L YL ++++H ++ N+ Sbjct 141 VIYLVLEYMDRGSLADIIKQVKTIL-EPYLAVLCKQVLEGLLYLHHERHVIHRDIKPSNL 199 Query 741 LLARLGLAEGTSPFIKLSDPG----VGLGALSREERVERIPWLAPECLPGGANSLSTAMD 796 L+ R G +K++D G + R+ V ++APE + G + D Sbjct 200 LVNRKGE-------VKITDFGVSAVLASSMGQRDTFVGTYNYMAPERISGSSYDY--KSD 250 Query 797 KWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLP---------EPSCPQLATLTSQ 847 W G +LE C G P FY+ + + P+ S Sbjct 251 IWSLGLVILE-CAIGRFPYIPSEGEGWLSFYELLEAIVDQPPPSAPADQFSPEFCAFISS 309 Query 848 CLTYEPTQRPSFRTILRDLT 867 C+ +P +R S +L Sbjct 310 CIQKDPAERMSASELLNHPF 329 >sp|P47197|AKT2_RAT RAC-beta serine/threonine-protein kinase OS=Rattus norvegicus OX=10116 GN=Akt2 PE=1 SV=1 Length=481 Score = 210 bits (535), Expect = 1e-57, Method: Composition-based stats. Identities = 66/273 (24%), Positives = 103/273 (38%), Gaps = 33/273 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960 LG+G FGKV L TG A+K L+ + + E +L+ H + Sbjct 158 LGKGTFGKVILV----REKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLT 213 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHY 1019 K Q L VMEY G L +L R + + +I + YLH+ Sbjct 214 ALKYAF--QTHDRLCFVMEYANGGDLFFHLSRERVFTEDRARFYGAEIVSALEYLHSTDV 271 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 ++RD+ N++LD D +KI DFGL+K EG + + APE L++ + Sbjct 272 VYRDIKLENLMLDKDGHIKITDFGLSK---EGISDGATMKTFCGTPEYLAPEVLEDNDYG 328 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 A D W GV +YE++ Q +L R PR Sbjct 329 RAVDWWGLGVVMYEMMCGRLPF--------------YNQDHERLFELILMEEIRFPR--T 372 Query 1140 CPCEVYHLMKNCWETEASFR----PT-FENLIP 1167 E L+ + + R P+ + ++ Sbjct 373 LGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVME 405 Score = 167 bits (422), Expect = 9e-43, Method: Composition-based stats. Identities = 62/308 (20%), Positives = 110/308 (36%), Gaps = 46/308 (15%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 P ++S +M A + R +V + L LG+GT V +R + + Sbjct 126 SPSDSSTSEMMEVAVSKAR---------AKVTMNDFDYLKLLGKGTFGKVI--LVREKAT 174 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 G K+ ++ ++ + + + ++ H L + Sbjct 175 GRYYAMKILRKEVIIAKDEVAHTVT-------------------ESRVLQNTRHPFLTAL 215 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHG 733 V EY G L L RER ++ SAL YL + ++V+ Sbjct 216 KYAFQTHDRLCFVMEYANGGDLFFHLSRER-VFTEDRARFYGAEIVSALEYLHSTDVVYR 274 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGAN 789 ++ N++L + G IK++D G+ +S + +LAPE L N Sbjct 275 DIKLENLMLDKDG-------HIKITDFGLSKEGISDGATMKTFCGTPEYLAPEVLED--N 325 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQC 848 A+D WG G + E+ G P ++ + R P P+ +L + Sbjct 326 DYGRAVDWWGLGVVMYEMMC-GRLPFYNQDHERLFELILMEEIRFPRTLGPEAKSLLAGL 384 Query 849 LTYEPTQR 856 L +P QR Sbjct 385 LKKDPKQR 392 >sp|P17801|KPRO_MAIZE Putative receptor protein kinase ZmPK1 OS=Zea mays OX=4577 GN=PK1 PE=2 SV=2 Length=817 Score = 218 bits (555), Expect = 1e-57, Method: Composition-based stats. Identities = 75/315 (24%), Positives = 118/315 (37%), Gaps = 26/315 (8%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 + + + K K +LG G G V + VAVK Sbjct 508 WASEKGYKAMTSNFRRYSYRELVKATRKFKVELGRGESGTVYKGVLE-----DDRHVAVK 562 Query 931 ALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL 990 L + Q + ++ E+ ++ + H ++++ G C + + LV EYV GSL + L Sbjct 563 KL--ENVRQGKEVFQAELSVIGRINHMNLVRIWGFCSEGSHR--LLVSEYVENGSLANIL 618 Query 991 PRHS----IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDRLVKIGDFG 1043 + A + +G+AYLH + IH D+ N+LLD KI DFG Sbjct 619 FSEGGNILLDWEGRFNIALGVAKGLAYLHHECLEWVIHCDVKPENILLDQAFEPKITDFG 678 Query 1044 LAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLT------- 1096 L K + G V + + APE + DV+S+GV L ELLT Sbjct 679 LVKLLNRGGSTQNV-SHVRGTLGYIAPEWVSSLPITAKVDVYSYGVVLLELLTGTRVSEL 737 Query 1097 --HCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWET 1154 D S K + ++ + L+ P + L +C E Sbjct 738 VGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDSKLNRPVNYVQARTLIKLAVSCLEE 797 Query 1155 EASFRPTFENLIPIL 1169 + S RPT E+ + L Sbjct 798 DRSKRPTMEHAVQTL 812 Score = 190 bits (482), Expect = 2e-48, Method: Composition-based stats. Identities = 60/301 (20%), Positives = 114/301 (38%), Gaps = 52/301 (17%) Query 544 CFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNV 603 F L+R P + + T N + S+ + + LG+G V Sbjct 495 FFVLKRELRP------SELWASEKGYKAMTSNFRRYSYRELVKATRKFKVELGRGESGTV 548 Query 604 YEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMS 663 Y+G L + V +K L + F S++ Sbjct 549 YKGVLEDDRH-------------------------VAVKKL-ENVRQGKEVFQAELSVIG 582 Query 664 QVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW--KMVVAQQLASA 721 +++H +L + G C G ++V+EYVE+G L L E G++ + W + +A +A Sbjct 583 RINHMNLVRIWGFCSEGSHRLLVSEYVENGSLANILFSEGGNILLDWEGRFNIALGVAKG 642 Query 722 LSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV------GLGALSREER 772 L+YL ++ ++H +V NILL + K++D G+ G + Sbjct 643 LAYLHHECLEWVIHCDVKPENILLDQAFEP-------KITDFGLVKLLNRGGSTQNVSHV 695 Query 773 VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHR 832 + ++APE + + ++ +D + +G LLE+ E ++ R Sbjct 696 RGTLGYIAPEWVS--SLPITAKVDVYSYGVVLLELLTGTRVSELVGGTDEVHSMLRKLVR 753 Query 833 L 833 + Sbjct 754 M 754 >sp|P18654|KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 OS=Mus musculus OX=10090 GN=Rps6ka3 PE=1 SV=2 Length=740 Score = 216 bits (551), Expect = 1e-57, Method: Composition-based stats. Identities = 65/279 (23%), Positives = 113/279 (41%), Gaps = 24/279 (9%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHR 941 + ++ LG+G FGKV L + ++ A+K LK + R Sbjct 54 HHVKEGHEKADPSQFELLKVLGQGSFGKVFLVK-KISGSDARQLYAMKVLKKATLKVRDR 112 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQL 1000 K E DIL + H I+K Q E L L+++++ G L L + + Sbjct 113 VRTKMERDILVEVNHPFIVKLHYAF--QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDV 170 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 + ++ + +LH+ I+RDL N+LLD + +K+ DFGL+K E ++ + Sbjct 171 KFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK---ESIDHEKKAYS 227 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 V + APE + ++D WSFGV ++E+LT Q K + + Sbjct 228 FCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILK----- 282 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 +L P E L++ ++ + R Sbjct 283 -----------AKLGMPQFLSPEAQSLLRMLFKRNPANR 310 Score = 189 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 68/293 (23%), Positives = 104/293 (35%), Gaps = 29/293 (10%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 + ++ + D+G G + + TN AVK + Sbjct 405 HSIVQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATN----MEFAVKIIDKS---- 456 Query 940 HRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GL 997 + +EI+IL H +II K +D K + +V E + G L D + R Sbjct 457 -KRDPTEEIEILLRYGQHPNIITLKDVYDDG--KYVYVVTELMKGGELLDKILRQKFFSE 513 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL-LDNDRL---VKIGDFGLAKAVPEGHE 1053 + I + + YLHAQ +HRDL N+L +D ++I DFG AK + + Sbjct 514 REASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENG 573 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 + APE LK + A D+WS GV LY +LT + P E I Sbjct 574 LLMT---PCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEIL 630 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 G L G D L+ + R T ++ Sbjct 631 ARIGSGKFS-----LSGGYWNSVSDTA----KDLVSKMLHVDPHQRLTAALVL 674 Score = 174 bits (441), Expect = 1e-43, Method: Composition-based stats. Identities = 61/340 (18%), Positives = 122/340 (36%), Gaps = 41/340 (12%) Query 526 VRELGAALQGCLLRAGDDCFSLRRCCLPQP--GETSNLIIMRGARASPRTLNLSQLSFHR 583 + +L Q + + D + + +P E N G+ + + + Sbjct 3 LAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEGSIKEIAITHHVKEGHEK 62 Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 D + L LGQG+ V+ ++ D L +KV Sbjct 63 ADPSQFELLKVLGQGSFGKVFL----------VKKISGSDARQLY-----------AMKV 101 Query 644 LDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 L + + ++ +V+H + +H + ++ +++ G L L + Sbjct 102 LKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK 161 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 E K +A +LA AL +L + +++ ++ NILL G IKL+D G Sbjct 162 EVMFTEEDVKFYLA-ELALALDHLHSLGIIYRDLKPENILLDEEG-------HIKLTDFG 213 Query 762 VGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + ++ E++ + ++APE + + + D W FG + E+ G P Q Sbjct 214 LSKESIDHEKKAYSFCGTVEYMAPEVV--NRRGHTQSADWWSFGVLMFEML-TGTLPFQG 270 Query 818 RSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQR 856 + E + +P+ P+ +L P R Sbjct 271 KDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANR 310 Score = 149 bits (376), Expect = 1e-35, Method: Composition-based stats. Identities = 53/291 (18%), Positives = 93/291 (32%), Gaps = 26/291 (9%) Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SHT 668 +G E+ + + + +K++D S D E ++ + H Sbjct 419 TDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPT----EEIEILLRYGQHP 474 Query 669 HLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK 728 ++ + V G +VTE ++ G L + R++ V + + YL + Sbjct 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKF-FSEREASAVLFTITKTVEYLHAQ 533 Query 729 NLVHGNVCGRNIL-LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL----APEC 783 +VH ++ NIL + G E I++ D G + + + APE Sbjct 534 GVVHRDLKPSNILYVDESGNPES----IRICDFGFAKQLRAENGLLMTPCYTANFVAPEV 589 Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPL---QSRSPSEKEHFYQRQHR-----LPE 835 L A D W G L + G P +P E Sbjct 590 LK--RQGYDAACDIWSLGVLLYTML-TGYTPFANGPDDTPEEILARIGSGKFSLSGGYWN 646 Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 L S+ L +P QR + +LR + L D+P Sbjct 647 SVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPH 697 >sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens OX=9606 GN=RPS6KA3 PE=1 SV=1 Length=740 Score = 216 bits (551), Expect = 1e-57, Method: Composition-based stats. Identities = 65/279 (23%), Positives = 113/279 (41%), Gaps = 24/279 (9%) Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHR 941 + ++ LG+G FGKV L + ++ A+K LK + R Sbjct 54 HHVKEGHEKADPSQFELLKVLGQGSFGKVFLVK-KISGSDARQLYAMKVLKKATLKVRDR 112 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQL 1000 K E DIL + H I+K Q E L L+++++ G L L + + Sbjct 113 VRTKMERDILVEVNHPFIVKLHYAF--QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDV 170 Query 1001 LLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 + ++ + +LH+ I+RDL N+LLD + +K+ DFGL+K E ++ + Sbjct 171 KFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK---ESIDHEKKAYS 227 Query 1061 GDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMT 1120 V + APE + ++D WSFGV ++E+LT Q K + + Sbjct 228 FCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILK----- 282 Query 1121 VLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 +L P E L++ ++ + R Sbjct 283 -----------AKLGMPQFLSPEAQSLLRMLFKRNPANR 310 Score = 189 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 68/293 (23%), Positives = 104/293 (35%), Gaps = 29/293 (10%) Query 880 VNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQ 939 + ++ + D+G G + + TN AVK + Sbjct 405 HSIVQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATN----MEFAVKIIDKS---- 456 Query 940 HRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GL 997 + +EI+IL H +II K +D K + +V E + G L D + R Sbjct 457 -KRDPTEEIEILLRYGQHPNIITLKDVYDDG--KYVYVVTELMKGGELLDKILRQKFFSE 513 Query 998 AQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL-LDNDRL---VKIGDFGLAKAVPEGHE 1053 + I + + YLHAQ +HRDL N+L +D ++I DFG AK + + Sbjct 514 REASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENG 573 Query 1054 YYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG 1113 + APE LK + A D+WS GV LY +LT + P E I Sbjct 574 LLMT---PCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEIL 630 Query 1114 IAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 G L G D L+ + R T ++ Sbjct 631 ARIGSGKFS-----LSGGYWNSVSDTA----KDLVSKMLHVDPHQRLTAALVL 674 Score = 173 bits (438), Expect = 3e-43, Method: Composition-based stats. Identities = 59/341 (17%), Positives = 122/341 (36%), Gaps = 43/341 (13%) Query 526 VRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNL---IIMRGARASPRTLNLSQLSFH 582 + +L Q + + D + + +P + + T ++ + Sbjct 3 LAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEVSIKEIAITHHVKEGH-E 61 Query 583 RVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK 642 + D + L LGQG+ V+ ++ D L +K Sbjct 62 KADPSQFELLKVLGQGSFGKVFL----------VKKISGSDARQLY-----------AMK 100 Query 643 VLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 VL + + ++ +V+H + +H + ++ +++ G L L Sbjct 101 VLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLS 160 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 +E K +A +LA AL +L + +++ ++ NILL G IKL+D Sbjct 161 KEVMFTEEDVKFYLA-ELALALDHLHSLGIIYRDLKPENILLDEEG-------HIKLTDF 212 Query 761 GVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 G+ ++ E++ + ++APE + + + D W FG + E+ G P Q Sbjct 213 GLSKESIDHEKKAYSFCGTVEYMAPEVV--NRRGHTQSADWWSFGVLMFEML-TGTLPFQ 269 Query 817 SRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQR 856 + E + +P+ P+ +L P R Sbjct 270 GKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANR 310 Score = 149 bits (376), Expect = 1e-35, Method: Composition-based stats. Identities = 53/291 (18%), Positives = 93/291 (32%), Gaps = 26/291 (9%) Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SHT 668 +G E+ + + + +K++D S D E ++ + H Sbjct 419 TDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPT----EEIEILLRYGQHP 474 Query 669 HLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK 728 ++ + V G +VTE ++ G L + R++ V + + YL + Sbjct 475 NIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKF-FSEREASAVLFTITKTVEYLHAQ 533 Query 729 NLVHGNVCGRNIL-LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL----APEC 783 +VH ++ NIL + G E I++ D G + + + APE Sbjct 534 GVVHRDLKPSNILYVDESGNPES----IRICDFGFAKQLRAENGLLMTPCYTANFVAPEV 589 Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPL---QSRSPSEKEHFYQRQHR-----LPE 835 L A D W G L + G P +P E Sbjct 590 LK--RQGYDAACDIWSLGVLLYTML-TGYTPFANGPDDTPEEILARIGSGKFSLSGGYWN 646 Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPA 886 L S+ L +P QR + +LR + L D+P Sbjct 647 SVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPH 697 >sp|Q8AXC6|KIT_TAKRU Mast/stem cell growth factor receptor Kit OS=Takifugu rubripes OX=31033 GN=kit PE=3 SV=1 Length=984 Score = 220 bits (560), Expect = 1e-57, Method: Composition-based stats. Identities = 92/421 (22%), Positives = 163/421 (39%), Gaps = 95/421 (23%) Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKK 899 + L L Y+ Q+P ++ + + + +N + F ++ L+ Sbjct 524 CILCLILIVLFYKYMQKPKYQIQWKVIEGIHGNNYVYIDPTQLPYDHQ--WEFPRKNLRF 581 Query 900 IRDLGEGHFGKVSLYC-YDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL-YHE 957 + LG G FGKV Y N+ + VAVK LK+ + E+ +L L H Sbjct 582 GKTLGSGAFGKVVEATAYGLANEDSMMTVAVKMLKSSAHSTEKEALMSELKVLIYLGNHI 641 Query 958 HIIK----------------------YKGCCEDQGEKSLQLVME----Y--------VPL 983 +I+ + E + +E Y + Sbjct 642 NIVNLLGACTVGGPTLVITEYCCFGDLLNFLRRKRESFICFKLEEDCHYRNIMLQREMAG 701 Query 984 GSLRDYLPRH----------------------------------------SIGLAQLLLF 1003 SL Y+ S+ LL F Sbjct 702 DSLNGYMTMRPSAAGKPSSSSSSEKRRSLREGSPYVEEDSESEMFDEDSLSLDTEDLLSF 761 Query 1004 AQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDS 1063 + Q+ +GM +L +++ IHRDLAARN+LL R+ KI DFGLA+ + Y V+ + Sbjct 762 SYQVAKGMEFLTSKNCIHRDLAARNILLTQGRVAKICDFGLARDINTDSNYV-VKGNARL 820 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 PV W +PE + E + + SDVWS+G+ L+E+ + +S G + Sbjct 821 PVKWMSPESIFECVYTFESDVWSYGILLWEIFSLGNSPY-------------PGMPVDAK 867 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183 +L++ G R+ P+ P E+Y +M++CW+ + RP F ++ + + ++ + Sbjct 868 FYKLIKEGYRMDAPEFAPSEMYQIMRSCWDADPLNRPPFRKVV---ERIEQQLSDTTKHI 924 Query 1184 F 1184 + Sbjct 925 Y 925 Score = 150 bits (378), Expect = 2e-35, Method: Composition-based stats. Identities = 40/221 (18%), Positives = 78/221 (35%), Gaps = 18/221 (8%) Query 689 YVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLA 748 YVE + + + + Q+A + +L +KN +H ++ RNILL + Sbjct 736 YVEEDSESEMFDEDSLSLDTEDLLSFSYQVAKGMEFLTSKNCIHRDLAARNILLTQ---- 791 Query 749 EGTSPFIKLSDPGVGLGALSREERVER------IPWLAPECLPGGANSLSTAMDKWGFGA 802 K+ D G+ + V + + W++PE + + D W +G Sbjct 792 ---GRVAKICDFGLARDINTDSNYVVKGNARLPVKWMSPESIFECVYTF--ESDVWSYGI 846 Query 803 TLLEICFDGEAPLQSRSPSEK-EHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSF 859 L EI G +P K + +R+ PE + ++ + C +P RP F Sbjct 847 LLWEIFSLGNSPYPGMPVDAKFYKLIKEGYRMDAPEFAPSEMYQIMRSCWDADPLNRPPF 906 Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKI 900 R ++ + + + P + + Sbjct 907 RKVVERIEQQLSDTTKHIYLNFSSRVPVMPRGREESSTHSM 947 Score = 88.2 bits (217), Expect = 3e-16, Method: Composition-based stats. Identities = 27/136 (20%), Positives = 45/136 (33%), Gaps = 21/136 (15%) Query 573 TLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRD 632 L +K + LG G V + G E M Sbjct 563 PTQLPYDHQWEFPRKNLRFGKTLGSGAFGKV----VEATAYGLANEDSM----------- 607 Query 633 RGQELRVVLKVLDPSHHDIALA-FYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690 + V +K+L S H ++ + +H ++ + G C G +++TEY Sbjct 608 ----MTVAVKMLKSSAHSTEKEALMSELKVLIYLGNHINIVNLLGACTVGGPTLVITEYC 663 Query 691 EHGPLDVWLRRERGHV 706 G L +LRR+R Sbjct 664 CFGDLLNFLRRKRESF 679 >sp|Q6Z8C8|CDKF4_ORYSJ Cyclin-dependent kinase F-4 OS=Oryza sativa subsp. japonica OX=39947 GN=CDKF-4 PE=2 SV=1 Length=459 Score = 209 bits (533), Expect = 1e-57, Method: Composition-based stats. Identities = 73/291 (25%), Positives = 120/291 (41%), Gaps = 29/291 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 K I+++G+G FG V + N GE+VAVK +K +E+ LR Sbjct 1 MDRFKMIKEVGDGTFGSV----WRAINKQNGEVVAVKKMKRKYYSFEECMSLREVKSLRR 56 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQLLLFAQQICEGM 1011 + H +I+K K + L +MEY+ +L + A++ + QI + + Sbjct 57 MNHPNIVKLKEVIREND--ILYFIMEYMEC-NLYQLMKDRVKPFSEAEVRNWCFQIFQAL 113 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 AY+H + Y HRDL N+L+ D ++K+ DFGLA+ V Y + S ++ APE Sbjct 114 AYMHQRGYFHRDLKPENLLVSKD-VIKLADFGLAREVTSVPPY----TEYVSTRWYRAPE 168 Query 1072 C-LKEYKFYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 L+ + A D+W+ G + ELLT S K +IG Q L+ Sbjct 169 VLLQSSIYDSAVDMWAMGAIMAELLTLHPLFPGTSEADEILKICNVIGSPDEQSWPQGLS 228 Query 1126 ELLERGERLPRPDK---------CPCEVYHLMKNCWETEASFRPTFENLIP 1167 + P+ E L+ + + RP ++ Sbjct 229 LAETMKFQFPQVSGNQLAEVMTSVSSEAVDLISSLCSWDPCKRPKAAEVLQ 279 Score = 162 bits (411), Expect = 2e-41, Method: Composition-based stats. Identities = 45/265 (17%), Positives = 86/265 (32%), Gaps = 38/265 (14%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + +G GT +V+ + G V +K + Sbjct 1 MDRFKMIKEVGDGTFGSVWRAINKQNGE------------------------VVAVKKMK 36 Query 646 PSHHDIALAF-YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 ++ + +++H ++ + V + EY+E L ++ Sbjct 37 RKYYSFEECMSLREVKSLRRMNHPNIVKLKEVIRENDILYFIMEYMEC-NLYQLMKDRVK 95 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 A Q+ AL+Y+ + H ++ N+L+++ IKL+D G+ Sbjct 96 PFSEAEVRNWCFQIFQALAYMHQRGYFHRDLKPENLLVSKD--------VIKLADFGLAR 147 Query 765 GALS---REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 S E V + APE L ++ +A+D W GA + E+ + Sbjct 148 EVTSVPPYTEYVSTRWYRAPEVLLQ-SSIYDSAVDMWAMGAIMAELLTLHPLFPGTSEAD 206 Query 822 EKEHFYQRQHRLPEPSCPQLATLTS 846 E E S PQ +L Sbjct 207 EILKICNVIGSPDEQSWPQGLSLAE 231 >sp|Q5RJI5|BRSK1_MOUSE Serine/threonine-protein kinase BRSK1 OS=Mus musculus OX=10090 GN=Brsk1 PE=1 SV=1 Length=778 Score = 217 bits (553), Expect = 1e-57, Method: Composition-based stats. Identities = 72/279 (26%), Positives = 117/279 (42%), Gaps = 29/279 (10%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDI 950 + + + LG+G G V L + TG+ VAVK + + ++EI I Sbjct 29 QYVGPYRLEKTLGKGQTGLVKLG----VHCITGQKVAVKIVNREKLSESVLMKVEREIAI 84 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICE 1009 L+ + H H++K E++ K L LV+E+V G L DYL + + + F +QI Sbjct 85 LKLIEHPHVLKLHDVYENK--KYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVS 142 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + + H+ HRDL N+LLD ++I DFG+A + E + Sbjct 143 ALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASL----QVGDSLLETSCGSPHYAC 198 Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE +K K+ +D+WS GV L+ LL + +L E + Sbjct 199 PEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDD---------------NLRQLLEKV 243 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 +RG P P + L++ E E R + E + Sbjct 244 KRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQK 281 Score = 169 bits (427), Expect = 9e-42, Method: Composition-based stats. Identities = 54/329 (16%), Positives = 101/329 (31%), Gaps = 44/329 (13%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647 LG+G V G + G +V +K+++ Sbjct 35 RLEKTLGKGQTGLVKLGVHCITGQ------------------------KVAVKIVNREKL 70 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 + + +++ + H H+ +H V +V E+V G L +L ++G + Sbjct 71 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYL-VKKGRLT 129 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 +Q+ SAL + + ++ H ++ N+LL I+++D G+ + Sbjct 130 PKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKN-------NIRIADFGMASLQV 182 Query 768 SR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 E + PE + G D W G L + G P + + Sbjct 183 GDSLLETSCGSPHYACPEVIKGEKYD-GRRADMWSCGVILFALLV-GALPFDDDNLRQLL 240 Query 825 HFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 +R +P P +L + EP +R S I + L + D Sbjct 241 EKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAP 300 Query 884 SPASDPTVFHKRYLKKIRDLGE----GHF 908 L G F Sbjct 301 GRRVAMRSLPSNGELDPDVLESMASLGCF 329 >sp|Q10N20|MPK5_ORYSJ Mitogen-activated protein kinase 5 OS=Oryza sativa subsp. japonica OX=39947 GN=MPK5 PE=1 SV=1 Length=369 Score = 207 bits (526), Expect = 1e-57, Method: Composition-based stats. Identities = 74/329 (22%), Positives = 116/329 (35%), Gaps = 34/329 (10%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 + + +Y I +G G +G V N T EMVA+ Sbjct 9 FRPTMTHGGRYLLYDIFGNKFEVTNKYQPPIMPIGRGAYGIVCSVM----NFETREMVAI 64 Query 930 KAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGS 985 K + A +EI +LR L HE+II + Q + + E + Sbjct 65 KKIANAFNNDMDAKRTLREIKLLRHLDHENIIGIRDVIPPPIPQAFNDVYIATELMD-TD 123 Query 986 LRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 L + + F QI G+ Y+H+ + IHRDL N+LL+ + +KI DFGL Sbjct 124 LHHIIRSNQELSEEHCQYFLYQILRGLKYIHSANVIHRDLKPSNLLLNANCDLKICDFGL 183 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFYYASDVWSFGVTLYELLTHCDSSQ- 1102 A+ E + + ++ APE L + A DVWS G EL+ Sbjct 184 ARPSSESD----MMTEYVVTRWYRAPELLLNSTDYSAAIDVWSVGCIFMELINRQPLFPG 239 Query 1103 ---------------SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 +P L I + + L + R P P + L Sbjct 240 RDHMHQMRLITEVIGTPTDDELGFIRNEDARKYMRHLPQYPRRTFASMFPRVQPAAL-DL 298 Query 1148 MKNCWETEASFRPTFENLI--PILKTVHE 1174 ++ R T E + P L+ +H+ Sbjct 299 IERMLTFNPLQRITVEEALDHPYLERLHD 327 Score = 125 bits (314), Expect = 1e-29, Method: Composition-based stats. Identities = 33/181 (18%), Positives = 67/181 (37%), Gaps = 22/181 (12%) Query 639 VVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYV 690 V +K + + D L+ + H ++ + V + + TE + Sbjct 62 VAIKKIANAFNNDMDAKRT-LREIKLLRHLDHENIIGIRDVIPPPIPQAFNDVYIATELM 120 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 + L +R + + Q+ L Y+ + N++H ++ N+LL Sbjct 121 D-TDLHHIIRSNQ-ELSEEHCQYFLYQILRGLKYIHSANVIHRDLKPSNLLLN------- 171 Query 751 TSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 + +K+ D G+ + + E V + APE L + S A+D W G +E+ Sbjct 172 ANCDLKICDFGLARPSSESDMMTEYVVTRWYRAPELLLNSTD-YSAAIDVWSVGCIFMEL 230 Query 808 C 808 Sbjct 231 I 231 >sp|A2XFC8|MPK5_ORYSI Mitogen-activated protein kinase 5 OS=Oryza sativa subsp. indica OX=39946 GN=MPK5 PE=1 SV=2 Length=369 Score = 207 bits (526), Expect = 1e-57, Method: Composition-based stats. Identities = 74/329 (22%), Positives = 116/329 (35%), Gaps = 34/329 (10%) Query 870 QPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAV 929 + + +Y I +G G +G V N T EMVA+ Sbjct 9 FRPTMTHGGRYLLYDIFGNKFEVTNKYQPPIMPIGRGAYGIVCSVM----NFETREMVAI 64 Query 930 KAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGS 985 K + A +EI +LR L HE+II + Q + + E + Sbjct 65 KKIANAFNNDMDAKRTLREIKLLRHLDHENIIGIRDVIPPPIPQAFNDVYIATELMD-TD 123 Query 986 LRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGL 1044 L + + F QI G+ Y+H+ + IHRDL N+LL+ + +KI DFGL Sbjct 124 LHHIIRSNQELSEEHCQYFLYQILRGLKYIHSANVIHRDLKPSNLLLNANCDLKICDFGL 183 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFYYASDVWSFGVTLYELLTHCDSSQ- 1102 A+ E + + ++ APE L + A DVWS G EL+ Sbjct 184 ARPSSESD----MMTEYVVTRWYRAPELLLNSTDYSAAIDVWSVGCIFMELINRQPLFPG 239 Query 1103 ---------------SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHL 1147 +P L I + + L + R P P + L Sbjct 240 RDHMHQMRLITEVIGTPTDDELGFIRNEDARKYMRHLPQYPRRTFASMFPRVQPAAL-DL 298 Query 1148 MKNCWETEASFRPTFENLI--PILKTVHE 1174 ++ R T E + P L+ +H+ Sbjct 299 IERMLTFNPLQRITVEEALDHPYLERLHD 327 Score = 125 bits (314), Expect = 1e-29, Method: Composition-based stats. Identities = 33/181 (18%), Positives = 67/181 (37%), Gaps = 22/181 (12%) Query 639 VVLKVLDP---SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYV 690 V +K + + D L+ + H ++ + V + + TE + Sbjct 62 VAIKKIANAFNNDMDAKRT-LREIKLLRHLDHENIIGIRDVIPPPIPQAFNDVYIATELM 120 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 + L +R + + Q+ L Y+ + N++H ++ N+LL Sbjct 121 D-TDLHHIIRSNQ-ELSEEHCQYFLYQILRGLKYIHSANVIHRDLKPSNLLLN------- 171 Query 751 TSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 + +K+ D G+ + + E V + APE L + S A+D W G +E+ Sbjct 172 ANCDLKICDFGLARPSSESDMMTEYVVTRWYRAPELLLNSTD-YSAAIDVWSVGCIFMEL 230 Query 808 C 808 Sbjct 231 I 231 >sp|B2DD29|BRSK1_RAT Serine/threonine-protein kinase BRSK1 OS=Rattus norvegicus OX=10116 GN=Brsk1 PE=1 SV=1 Length=778 Score = 217 bits (553), Expect = 1e-57, Method: Composition-based stats. Identities = 72/279 (26%), Positives = 117/279 (42%), Gaps = 29/279 (10%) Query 892 FHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQEIDI 950 + + + LG+G G V L + TG+ VAVK + + ++EI I Sbjct 29 QYVGPYRLEKTLGKGQTGLVKLG----VHCITGQKVAVKIVNREKLSESVLMKVEREIAI 84 Query 951 LRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQICE 1009 L+ + H H++K E++ K L LV+E+V G L DYL + + + F +QI Sbjct 85 LKLIEHPHVLKLHDVYENK--KYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVS 142 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + + H+ HRDL N+LLD ++I DFG+A + E + Sbjct 143 ALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASL----QVGDSLLETSCGSPHYAC 198 Query 1070 PECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELL 1128 PE +K K+ +D+WS GV L+ LL + +L E + Sbjct 199 PEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDD---------------NLRQLLEKV 243 Query 1129 ERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 +RG P P + L++ E E R + E + Sbjct 244 KRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQK 281 Score = 169 bits (427), Expect = 9e-42, Method: Composition-based stats. Identities = 54/329 (16%), Positives = 101/329 (31%), Gaps = 44/329 (13%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647 LG+G V G + G +V +K+++ Sbjct 35 RLEKTLGKGQTGLVKLGVHCITGQ------------------------KVAVKIVNREKL 70 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 + + +++ + H H+ +H V +V E+V G L +L ++G + Sbjct 71 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYL-VKKGRLT 129 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 +Q+ SAL + + ++ H ++ N+LL I+++D G+ + Sbjct 130 PKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKN-------NIRIADFGMASLQV 182 Query 768 SR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 E + PE + G D W G L + G P + + Sbjct 183 GDSLLETSCGSPHYACPEVIKGEKYD-GRRADMWSCGVILFALLV-GALPFDDDNLRQLL 240 Query 825 HFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 +R +P P +L + EP +R S I + L + D Sbjct 241 EKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWYLGGKHEPDPCLEPAP 300 Query 884 SPASDPTVFHKRYLKKIRDLGE----GHF 908 L G F Sbjct 301 GRRVAMRSLPSNGELDPDVLESMASLGCF 329 >sp|P13863|CDK1_CHICK Cyclin-dependent kinase 1 OS=Gallus gallus OX=9031 GN=CDK1 PE=1 SV=1 Length=303 Score = 204 bits (520), Expect = 1e-57, Method: Composition-based stats. Identities = 63/287 (22%), Positives = 120/287 (42%), Gaps = 29/287 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ Sbjct 1 MEDYTKIEKIGEGTYGVV----YKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQIC 1008 L+H +I+ + + L L+ E++ + L+ YL + +++ + QI Sbjct 57 ELHHPNIVCLQDVLMQ--DARLYLIFEFLSM-DLKKYLDTIPSGQYLDRSRVKSYLYQIL 113 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +G+ + H++ +HRDL +N+L+D+ ++K+ DFGLA+A RV +++ Sbjct 114 QGIVFCHSRRVLHRDLKPQNLLIDDKGVIKLADFGLARAFGIP---VRVYTHEVVTLWYR 170 Query 1069 APECLKEYK-FYYASDVWSFGVTLYELLT-----HCDSSQSPPTKFLELIGIAQGQM--- 1119 +PE L + D+WS G EL T H DS + +G + Sbjct 171 SPEVLLGSALYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNDVWPD 230 Query 1120 -----TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 + G + L+ + + R + Sbjct 231 VESLQDYKNTFPKWKPGSLGTHVQNLDEDGLDLLSKMLIYDPAKRIS 277 Score = 162 bits (411), Expect = 5e-43, Method: Composition-based stats. Identities = 41/267 (15%), Positives = 95/267 (36%), Gaps = 41/267 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ T++ +G+GT VY+GR + G V +K + Sbjct 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQ------------------------VVAMKKIR 36 Query 646 PSHHD--IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-- 701 + + SL+ ++ H ++ + V ++ ++ E++ L +L Sbjct 37 LESEEEGVPSTAIREISLLKELHHPNIVCLQDVLMQDARLYLIFEFLSM-DLKKYLDTIP 95 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 ++ + Q+ + + ++ ++H ++ +N+L+ G+ IKL+D G Sbjct 96 SGQYLDRSRVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGV-------IKLADFG 148 Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + V + + +PE L G+ ST +D W G E+ Sbjct 149 LARAFGIPVRVYTHEVVTLWYRSPEVLL-GSALYSTPVDIWSIGTIFAELATKKPLFHGD 207 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ P + +L Sbjct 208 SEIDQLFRIFRALGTPNNDVWPDVESL 234 >sp|P29618|CDKA1_ORYSJ Cyclin-dependent kinase A-1 OS=Oryza sativa subsp. japonica OX=39947 GN=CDKA-1 PE=1 SV=1 Length=294 Score = 204 bits (519), Expect = 1e-57, Method: Composition-based stats. Identities = 69/295 (23%), Positives = 123/295 (42%), Gaps = 33/295 (11%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K +GEG +G V Y + T E +A+K ++ + + S +EI +L+ Sbjct 1 MEQYEKEEKIGEGTYGVV----YRARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009 ++H +I++ EK + LV EY+ L L+ ++ P + + + QI Sbjct 57 EMHHGNIVRLHDVI--HSEKRIYLVFEYLDL-DLKKFMDSCPEFAKNPTLIKSYLYQILR 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 G+AY H+ +HRDL +N+L+D +K+ DFGLA+A R +++ Sbjct 114 GVAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIP---VRTFTHEVVTLWYR 170 Query 1069 APECLKE-YKFYYASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIGIAQGQMTVL 1122 APE L ++ D+WS G E++ DS K ++G Q + Sbjct 171 APEILLGSRQYSTPVDMWSVGCIFAEMVNQKPLFPGDSEIDELFKIFRVLGTPNEQ-SWP 229 Query 1123 RLTELLERGERLPR----------PDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 ++ L + P+ P P + L+ E + R T + Sbjct 230 GVSSLPDYKSAFPKWQAQDLATIVPTLDPAGL-DLLSKMLRYEPNKRITARQALE 283 Score = 159 bits (401), Expect = 8e-42, Method: Composition-based stats. Identities = 47/266 (18%), Positives = 92/266 (35%), Gaps = 39/266 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 ++ + +G+GT VY RD+ + LK Sbjct 1 MEQYEKEEKIGEGTYGVVYRA------------------------RDKVTNETIALKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702 L+ + SL+ ++ H ++ +H V +V EY++ L ++ Sbjct 37 LEQEDEGVPSTAIREISLLKEMHHGNIVRLHDVIHSEKRIYLVFEYLDL-DLKKFMDSCP 95 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 Q+ ++Y + ++H ++ +N+L+ R A +KL+D G+ Sbjct 96 EFAKNPTLIKSYLYQILRGVAYCHSHRVLHRDLKPQNLLIDRRTNA------LKLADFGL 149 Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + + APE L G+ ST +D W G E+ Sbjct 150 ARAFGIPVRTFTHEVVTLWYRAPEILL-GSRQYSTPVDMWSVGCIFAEMVNQKPLFPGDS 208 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844 E ++ E S P +++L Sbjct 209 EIDELFKIFRVLGTPNEQSWPGVSSL 234 >sp|A3EZ55|HOG1A_WALI9 Mitogen-activated protein kinase HOG1A OS=Wallemia ichthyophaga (strain EXF-994 / CBS 113033) OX=1299270 GN=HOG1A PE=1 SV=2 Length=365 Score = 206 bits (525), Expect = 1e-57, Method: Composition-based stats. Identities = 62/297 (21%), Positives = 112/297 (38%), Gaps = 29/297 (10%) Query 887 SDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA-LKADCGPQHRSGWK 945 ++ +G G FG + T+ +G VA+K +K P Sbjct 14 FGNIFQVTTRYTDLQPVGMGAFGLLC----SSTDQKSGGPVAIKKVMKPFSAPVLAKRTY 69 Query 946 QEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQ 1005 +E+ +L+ L HE+II GE + + E + L L + + F Sbjct 70 RELKLLKHLRHENIISLLDVFISPGED-IYFITELL-GTDLHRLLSSRPLERQFVQYFLY 127 Query 1006 QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 Q+ + ++H +HRDL N+L++ + +KI DFGLA+ Y S Sbjct 128 QMLRALKFVHPAGVVHRDLKPSNILINENCDLKICDFGLARLQDPQMTGY------VSTR 181 Query 1066 FWYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM 1119 ++ APE + ++ + A D+WS G E++ T EL+G + Sbjct 182 YYRAPEIMLTWQEYDSAVDIWSVGCIFAEMIDGRPIFPGKDHVHQLTVITELLGSPPEDV 241 Query 1120 TV-------LRLTELLERGERLPRPDKCP---CEVYHLMKNCWETEASFRPTFENLI 1166 R + L + ++ D+ P E L++ + R T + + Sbjct 242 INTITSENTRRFVDALPKRHKISFADRFPNANAEEIDLLEKMLDFNPKKRITAADAL 298 Score = 133 bits (335), Expect = 2e-32, Method: Composition-based stats. Identities = 41/229 (18%), Positives = 78/229 (34%), Gaps = 19/229 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 N+++ R G L D+ V +K V+ P +A Y Sbjct 14 FGNIFQVTTRYTDLQPVGMGAF---GLLCSSTDQKSGGPVAIKKVMKPFSAPVLAKRTYR 70 Query 658 TASLMSQVSHTHLAFVHGVCVR-GPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + V + G + +TE + L L + + Sbjct 71 ELKLLKHLRHENIISLLDVFISPGEDIYFITELL-GTDLHRLLSSR--PLERQFVQYFLY 127 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE-RVER 775 Q+ AL ++ +VH ++ NIL+ + +K+ D G+ + V Sbjct 128 QMLRALKFVHPAGVVHRDLKPSNILINE-------NCDLKICDFGLARLQDPQMTGYVST 180 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 + APE + +A+D W G E+ DG + + Sbjct 181 RYYRAPE-IMLTWQEYDSAVDIWSVGCIFAEMI-DGRPIFPGKDHVHQL 227 >sp|Q17446|PMK1_CAEEL Mitogen-activated protein kinase pmk-1 OS=Caenorhabditis elegans OX=6239 GN=pmk-1 PE=1 SV=1 Length=377 Score = 207 bits (526), Expect = 1e-57, Method: Composition-based stats. Identities = 64/327 (20%), Positives = 114/327 (35%), Gaps = 34/327 (10%) Query 863 LRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDG 922 + T + + Y + +G G +G V Sbjct 1 MFPQTTMDHILHPTPREGYYVVELNRSVWVVPNYYINLTPIGTGAYGTVCA----AECTR 56 Query 923 TGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGE----KSLQLV 977 +G VA+K + H +E+ +LR + HE+II + + V Sbjct 57 SGTRVAIKKFNRPFQSIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFV 116 Query 978 MEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLV 1037 + L + L + + QI G+ Y+H+ IHRDL N+ ++ D + Sbjct 117 SMLM-GADLSNILKIQRLNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNIAVNEDCEL 175 Query 1038 KIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY-KFYYASDVWSFGVTLYELLT 1096 KI DFGLA+ Y + ++ APE + + + DVWS G L EL+T Sbjct 176 KILDFGLARQTDSEMTGY------VATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELIT 229 Query 1097 HCDSSQ----------------SPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 +P +FL+ I + + + L ++ R + Sbjct 230 GKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQAT 289 Query 1141 PCEVYHLMKNCWETEASFRPTFENLIP 1167 P + L++ + RPT + + Sbjct 290 PQAI-DLLEKMLHLDPDRRPTAKEAME 315 Score = 120 bits (302), Expect = 6e-28, Method: Composition-based stats. Identities = 56/359 (16%), Positives = 97/359 (27%), Gaps = 75/359 (21%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 L+ +G G V G RV +K + Sbjct 36 INLTPIGTGAYGTVCAAECTRSG------------------------TRVAIKKFNRPFQ 71 Query 650 DI--ALAFYETASLMSQVSHTHLAFVHGVCV------RGPENIMVTEYVEHGPLDVWLRR 701 I A Y L+ + H ++ + V + V+ + L L+ Sbjct 72 SIIHARRTYRELRLLRCMCHENIIDLLDVFTPNENVNDIEDVYFVSMLM-GADLSNILKI 130 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 +R + + Q+ L Y+ + +++H ++ NI A +K+ D G Sbjct 131 QR--LNDDHIQFLVYQILRGLKYIHSADIIHRDLKPSNI-------AVNEDCELKILDFG 181 Query 762 VGLGALSREERVERIPWL-APECLPGGANSLSTAMDKWGFGATLLEICF----------- 809 + S W APE + + +D W G L E+ Sbjct 182 LARQTDSEMTGYVATRWYRAPE-IMLNWMHYTQTVDVWSVGCILAELITGKTLFPGSDHI 240 Query 810 ---------DGEAPLQSRSPSEKEHFYQRQHRLPEPS-----------CPQLATLTSQCL 849 G + E LP+ + PQ L + L Sbjct 241 DQLTRIMSVTGTPDEEFLKKISSEEARNYIRNLPKMTRRDFKRLFAQATPQAIDLLEKML 300 Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHF 908 +P +RP+ + + H+ D D KKI F Sbjct 301 HLDPDRRPTAKEAMEHEYLAAYHDETDEPIAEEMDLNDDVRADTIDEWKKIIWEEISDF 359 >sp|Q2U469|MPKC_ASPOR Mitogen-activated protein kinase mpkC OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=mpkC PE=3 SV=2 Length=344 Score = 206 bits (523), Expect = 2e-57, Method: Composition-based stats. Identities = 67/285 (24%), Positives = 107/285 (38%), Gaps = 31/285 (11%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VAVK + +E+ +L+ L HE++ Sbjct 23 QPVGLGAFGLVC----SAYDQITQQHVAVKKMMNPFANASIAKRTYREVKLLKQLRHENL 78 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + LV E + L L + F QI G+ Y+H+ Sbjct 79 IGLCDIFISPLED-IYLVTELL-GTDLGRLLRARPLDNKFAQYFMYQILRGLKYIHSAGV 136 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 IHRDL N+L++ + +KI DFGLA+ Y S ++ APE + ++ Sbjct 137 IHRDLKPSNLLVNENCDLKICDFGLARVQEPQMTGY------VSTRYYRAPEIMLTWQRY 190 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGIAQGQMTVL 1122 D+WS G L E+L +PP + ++ I Q V Sbjct 191 GKMVDIWSAGCILAEMLRGKPLFPGKDHIHQFFLITEVLGNPPPEVVQKITSGNTQRVVN 250 Query 1123 RLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 L R R + +V L++ + R T E + Sbjct 251 SLPNQEPRPLR-AVFHEFDNDVISLLEQLLLFDPDKRLTAETALQ 294 Score = 139 bits (351), Expect = 1e-34, Method: Composition-based stats. Identities = 40/243 (16%), Positives = 84/243 (35%), Gaps = 24/243 (10%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDP 646 E + LG T + + + + D+ + V +K +++P Sbjct 2 EFIRAEILGT-TFET-------TSRYANVQPVGLGAFGLVCSAYDQITQQHVAVKKMMNP 53 Query 647 -SHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERG 704 ++ IA Y L+ Q+ H +L + + + + +VTE + L LR Sbjct 54 FANASIAKRTYREVKLLKQLRHENLIGLCDIFISPLEDIYLVTELL-GTDLGRLLRAR-- 110 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + Q+ L Y+ + ++H ++ N+L+ + +K+ D G+ Sbjct 111 PLDNKFAQYFMYQILRGLKYIHSAGVIHRDLKPSNLLVNE-------NCDLKICDFGLAR 163 Query 765 -GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 V + APE + +D W G L E+ G+ + + Sbjct 164 VQEPQMTGYVSTRYYRAPE-IMLTWQRYGKMVDIWSAGCILAEML-RGKPLFPGKDHIHQ 221 Query 824 EHF 826 Sbjct 222 FFL 224 >sp|Q91820|AURAA_XENLA Aurora kinase A-A OS=Xenopus laevis OX=8355 GN=aurka-a PE=1 SV=1 Length=407 Score = 208 bits (529), Expect = 2e-57, Method: Composition-based stats. Identities = 59/272 (22%), Positives = 107/272 (39%), Gaps = 30/272 (11%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQH--RSGWKQEI 948 + + R LG+G FG V L + ++A+K L + ++E+ Sbjct 134 QWCLEDFEIGRPLGKGKFGNVYL----ARERESKFILALKVLFKSQLEKAGVEHQLRREV 189 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQI 1007 +I L H +I++ G D + L+++Y P G L L + + ++ +Q+ Sbjct 190 EIQSHLRHPNILRLYGYFHDAS--RVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQL 247 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 E + Y H++ IHRD+ N+LL ++ +KI DFG + P R + + Sbjct 248 AEALLYCHSKKVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSR-----RTTLCGTLDY 302 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 PE ++ D+WS GV YE L ++ Q T R++++ Sbjct 303 LPPEMIEGRMHDETVDLWSLGVLCYEFLVGKPPFETD-----------THQETYRRISKV 351 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 P E L+ + + R Sbjct 352 -----EFQYPPYVSEEARDLVSKLLKHNPNHR 378 Score = 183 bits (464), Expect = 5e-49, Method: Composition-based stats. Identities = 56/291 (19%), Positives = 108/291 (37%), Gaps = 41/291 (14%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDP 646 ++ LG+G NVY R+R + + LKVL Sbjct 138 EDFEIGRPLGKGKFGNVYLA------------------------RERESKFILALKVLFK 173 Query 647 SHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 S + + + S + H ++ ++G ++ +Y G L L++ Sbjct 174 SQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDASRVYLILDYAPGGELFRELQK-C 232 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + +QLA AL Y +K ++H ++ N+LL G++ +K++D G Sbjct 233 TRFDDQRSAMYIKQLAEALLYCHSKKVIHRDIKPENLLL-------GSNGELKIADFGWS 285 Query 764 LGALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + A S R + +L PE + G + +D W G E G+ P ++ + Sbjct 286 VHAPSSRRTTLCGTLDYLPPEMIEGRMH--DETVDLWSLGVLCYEFLV-GKPPFETDTHQ 342 Query 822 EK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 E + + + P + L S+ L + P R + +L ++ Sbjct 343 ETYRRISKVEFQYPPYVSEEARDLVSKLLKHNPNHRLPLKGVLEHPWIIKN 393 >sp|Q0IHQ8|STK10_XENTR Serine/threonine-protein kinase 10 OS=Xenopus tropicalis OX=8364 GN=stk10 PE=2 SV=1 Length=951 Score = 219 bits (559), Expect = 2e-57, Method: Composition-based stats. Identities = 77/307 (25%), Positives = 133/307 (43%), Gaps = 32/307 (10%) Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 + + + + I +LG+G FGKV Y N TG + A K ++ + Sbjct 21 REYEHVRRDLDPNQVWEIIGELGDGAFGKV----YKAKNKETGILAAAKVIETK-NEEEL 75 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR--HSIGLAQ 999 + EI+IL T H I+K G +G+ L +++E+ P G++ + + + Sbjct 76 EDYMVEIEILATCNHHFIVKLLGSYYWEGK--LWIMIEFCPGGAVDAIMLELDRGLKEPE 133 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 + +Q+ EG+ YLH+ IHRDL A NVLL D +K+ DFG++ + + + R+ Sbjct 134 IRTICRQMLEGLTYLHSMKMIHRDLKAGNVLLTLDGDIKLADFGVS---AKNVKTLQRRD 190 Query 1060 DGDSPVFWYAPEC-----LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGI 1114 +W APE +K+ + Y +D+WS G+TL E+ + L+ I Sbjct 191 SFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIEMA-QIEPPHHELNPMRVLLKI 249 Query 1115 AQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 A+ + L P K E ++ +K + RP+ L+ + Sbjct 250 AKSEPPT------------LSSPSKWSPEFHNFLKTALDKNPETRPSAAQLLEH--PFVK 295 Query 1175 KYQGQAP 1181 K G P Sbjct 296 KVSGNKP 302 Score = 176 bits (445), Expect = 2e-43, Method: Composition-based stats. Identities = 54/350 (15%), Positives = 108/350 (31%), Gaps = 45/350 (13%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 + LG G VY+ + + G + KV++ + Sbjct 37 EIIGELGDGAFGKVYKAKNKETG------------------------ILAAAKVIETKNE 72 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 + + +++ +H + + G + ++ E+ G +D + + Sbjct 73 EELEDYMVEIEILATCNHHFIVKLLGSYYWEGKLWIMIEFCPGGAVDAIMLELDRGLKEP 132 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG----LG 765 + +Q+ L+YL + ++H ++ N+LL IKL+D GV Sbjct 133 EIRTICRQMLEGLTYLHSMKMIHRDLKAGNVLLT-------LDGDIKLADFGVSAKNVKT 185 Query 766 ALSREERVERIPWLAPECLP---GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 R+ + W+APE + D W G TL+E+ E P +P Sbjct 186 LQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIEMA-QIEPPHHELNPMR 244 Query 823 KEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTI--LRDLTRLQPHNLAD 876 + P P+ L P RPS + + ++ + Sbjct 245 VLLKIAKSEPPTLSSPSKWSPEFHNFLKTALDKNPETRPSAAQLLEHPFVKKVSGNKPLR 304 Query 877 VLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926 L + D + ++ VS + TG+ Sbjct 305 DLVAEAKAEVLDEIEENGEVEEEEASDTPSSNKSVSQSALGEKDKHTGKE 354 >sp|Q38773|CDC2B_ANTMA Cell division control protein 2 homolog B (Fragment) OS=Antirrhinum majus OX=4151 GN=CDC2B PE=2 SV=1 Length=280 Score = 203 bits (517), Expect = 2e-57, Method: Composition-based stats. Identities = 70/280 (25%), Positives = 117/280 (42%), Gaps = 29/280 (10%) Query 907 HFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILRTLYHEHIIKYKGC 965 +G V Y + T E +A+K ++ + + S +EI +L+ ++HE+I+ K Sbjct 1 AYGVV----YKARDIETNEDIALKKIRLEQEDEGVPSTAIREISLLKEMHHENIVNLKDV 56 Query 966 CEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHAQHYIHR 1022 EK L LV EY+ L L+ ++ P S L + +F QI G+AY H+ +HR Sbjct 57 VHR--EKRLYLVFEYLDL-DLKKHMDSCPEFSQDLHMVKMFLCQILRGVAYCHSHRVLHR 113 Query 1023 DLAARNVLLD-NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK-FYY 1080 DL +N+L+D +K+ DFGLA+A R +++ APE L + + Sbjct 114 DLKPQNLLIDRGSNTIKLADFGLARAFGIP---VRTFTHEVVTLWYRAPEVLLGSRHYST 170 Query 1081 ASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 DVWS G E++ DS K +IG + + + Sbjct 171 PVDVWSVGCIFAEMVNQKPLFPGDSEIDELHKIFRIIGTPNEDIWPGVTSLPDFKSSFPK 230 Query 1136 RPDKCPCEV--------YHLMKNCWETEASFRPTFENLIP 1167 P K + L+ + + S R T + + Sbjct 231 WPPKELATIVPNLGATGLDLLCKMLQLDPSKRITAKKALE 270 Score = 151 bits (381), Expect = 2e-39, Method: Composition-based stats. Identities = 42/226 (19%), Positives = 81/226 (36%), Gaps = 15/226 (7%) Query 626 PLVPGRDRGQELRVVLK--VLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPEN 683 + RD + LK L+ + SL+ ++ H ++ + V R Sbjct 4 VVYKARDIETNEDIALKKIRLEQEDEGVPSTAIREISLLKEMHHENIVNLKDVVHREKRL 63 Query 684 IMVTEYVEHGPLDVWLRR-ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILL 742 +V EY++ L + + + Q+ ++Y + ++H ++ +N+L+ Sbjct 64 YLVFEYLDL-DLKKHMDSCPEFSQDLHMVKMFLCQILRGVAYCHSHRVLHRDLKPQNLLI 122 Query 743 ARLGLAEGTSPFIKLSDPGVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKW 798 R S IKL+D G+ + V + + APE L G+ ST +D W Sbjct 123 DR------GSNTIKLADFGLARAFGIPVRTFTHEVVTLWYRAPEVLL-GSRHYSTPVDVW 175 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATL 844 G E+ E ++ E P + +L Sbjct 176 SVGCIFAEMVNQKPLFPGDSEIDELHKIFRIIGTPNEDIWPGVTSL 221 >sp|Q9LSR8|LRK19_ARATH L-type lectin-domain containing receptor kinase I.9 OS=Arabidopsis thaliana OX=3702 GN=LECRK19 PE=1 SV=2 Length=766 Score = 217 bits (552), Expect = 2e-57, Method: Composition-based stats. Identities = 74/279 (27%), Positives = 121/279 (43%), Gaps = 22/279 (8%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LG+G FG+V N G +AVK + + G + + E+ +R L H +++ Sbjct 349 FLGKGGFGEVYRG-----NLPQGREIAVKRVSHN-GDEGVKQFVAEVVSMRCLKHRNLVP 402 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICEGMAYLHA-- 1016 G C + E L LV EY+P GSL ++L + + +Q L+ + I + YLH Sbjct 403 LFGYCRRKRE--LLLVSEYMPNGSLDEHLFDDQKPVLSWSQRLVVVKGIASALWYLHTGA 460 Query 1017 -QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 Q +HRD+ A N++LD + ++GDFG+A+ G V + APE + Sbjct 461 DQVVLHRDVKASNIMLDAEFHGRLGDFGMARFHEHGGNAATT--AAVGTVGYMAPELI-T 517 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 +DV++FGV + E+ C P +E + + + LL+ + Sbjct 518 MGASTGTDVYAFGVFMLEV--TCGRRPVEPQLQVEKRHMIKWVCECWKKDSLLDATDPRL 575 Query 1136 RPDKCPCEVYHLMK---NCWETEASFRPTFENLIPILKT 1171 EV +MK C RPT E ++ L Sbjct 576 GGKFVAEEVEMVMKLGLLCSNIVPESRPTMEQVVLYLNK 614 Score = 213 bits (542), Expect = 3e-56, Method: Composition-based stats. Identities = 68/305 (22%), Positives = 118/305 (39%), Gaps = 63/305 (21%) Query 585 DQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL 644 K ++ LG+G VY G L Q + +K + Sbjct 340 ATKGFSKDEFLGKGGFGEVYRGNL-------------------------PQGREIAVKRV 374 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR-RER 703 + + F M + H +L + G C R E ++V+EY+ +G LD L ++ Sbjct 375 SHNGDEGVKQFVAEVVSMRCLKHRNLVPLFGYCRRKRELLLVSEYMPNGSLDEHLFDDQK 434 Query 704 GHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + + ++VV + +ASAL YL ++ ++H +V NI+L +L D Sbjct 435 PVLSWSQRLVVVKGIASALWYLHTGADQVVLHRDVKASNIMLD-------AEFHGRLGDF 487 Query 761 GVGL-----GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL 815 G+ G + V + ++APE + GA ST D + FG +LE+ G P+ Sbjct 488 GMARFHEHGGNAATTAAVGTVGYMAPELITMGA---STGTDVYAFGVFMLEV-TCGRRPV 543 Query 816 QSRSPSEKEHF------YQRQHRLPEPSCPQL------------ATLTSQCLTYEPTQRP 857 + + EK H ++ L + + P+L L C P RP Sbjct 544 EPQLQVEKRHMIKWVCECWKKDSLLDATDPRLGGKFVAEEVEMVMKLGLLCSNIVPESRP 603 Query 858 SFRTI 862 + + Sbjct 604 TMEQV 608 >sp|Q9FFP9|SRK2H_ARATH Serine/threonine-protein kinase SRK2H OS=Arabidopsis thaliana OX=3702 GN=SRK2H PE=1 SV=1 Length=360 Score = 206 bits (524), Expect = 2e-57, Method: Composition-based stats. Identities = 77/290 (27%), Positives = 123/290 (42%), Gaps = 29/290 (10%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 DLG G+FG L + T E+VA+K + + G + +EI R+L H +II+ Sbjct 9 DLGAGNFGVARLL----RHKETKELVAMKYI--ERGRKIDENVAREIINHRSLRHPNIIR 62 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEGMAYLHAQHYI 1020 +K L +VMEY G L + + A+ F QQ+ G+ Y H+ Sbjct 63 FKEVILTPTH--LAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQIC 120 Query 1021 HRDLAARNVLLDND--RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 HRDL N LLD L+KI DFG +K + R + +P + APE L ++ Sbjct 121 HRDLKLENTLLDGSPAPLLKICDFGYSK---SSLLHSRPKSTVGTPA-YIAPEVLSRREY 176 Query 1079 YYA-SDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 +DVWS GVTLY +L + P I + ++ + + Sbjct 177 DGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYV--------- 227 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLIP---ILKTVHEKYQGQAPSVF 1184 E HL+ + T ++ R T + + LK + ++ A + + Sbjct 228 -HISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAY 276 Score = 150 bits (379), Expect = 3e-38, Method: Composition-based stats. Identities = 47/282 (17%), Positives = 88/282 (31%), Gaps = 17/282 (6%) Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYV 690 R + + V +K ++ I + H ++ V + +V EY Sbjct 22 RHKETKELVAMKYIERG-RKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYA 80 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L + G A QQL + Y + + H ++ N LL Sbjct 81 SGGELFERI-CNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLD-----GS 134 Query 751 TSPFIKLSDPGVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEI 807 +P +K+ D G +L + V ++APE L D W G TL + Sbjct 135 PAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYD-GKHADVWSCGVTLYVM 193 Query 808 CFDGEAPLQSRSPSE----KEHFYQRQHRLPE--PSCPQLATLTSQCLTYEPTQRPSFRT 861 G P + Q+++P+ + L S+ +R + + Sbjct 194 LVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKE 253 Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDL 903 I + L+ + F + ++ I + Sbjct 254 IKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKI 295 >sp|F4JBP3|ATG1B_ARATH Serine/threonine-protein kinase ATG1b OS=Arabidopsis thaliana OX=3702 GN=ATG1B PE=2 SV=1 Length=711 Score = 216 bits (549), Expect = 2e-57, Method: Composition-based stats. Identities = 72/270 (27%), Positives = 117/270 (43%), Gaps = 33/270 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G F V ++ + G +VA+K + A + + EI ILR + H +II+ Sbjct 26 IGSGSFSVV----WEGRHLVHGTVVAIKEIAMARLNKKLQESLMSEIIILRKINHPNIIR 81 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH-SIGLAQLLLFAQQICEGMAYLHAQHYI 1020 + E G+ + LV+EY G L Y+ +H S+ A F Q+ G+ L + I Sbjct 82 FIDMIEAPGK--INLVLEYCKGGDLSMYIHKHGSVPEATAKHFMLQLAAGLQVLRDNNII 139 Query 1021 HRDLAARNVLL---DNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 HRDL +N+LL DND +KI DFG A+++ + E + APE ++ K Sbjct 140 HRDLKPQNLLLSTDDNDAALKIADFGFARSLQPRG----LAETLCGSPLYMAPEIMQLQK 195 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + +D+WS G L++L+T + ++L + + R L P Sbjct 196 YDAKADLWSVGAILFQLVTGRTPFT---------------GNSQIQLLQNIIRSTELHFP 240 Query 1138 DKC---PCEVYHLMKNCWETEASFRPTFEN 1164 C + L + R TFE Sbjct 241 ADCRDLSTDCKDLCQKLLRRNPVERLTFEE 270 Score = 186 bits (473), Expect = 9e-48, Method: Composition-based stats. Identities = 54/326 (17%), Positives = 110/326 (34%), Gaps = 38/326 (12%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + +G G+ + V+EGR V G+ + + + L+ Sbjct 19 DYAVGRQIGSGSFSVVWEGRHLVHGTVVAIK-------------------EIAMARLNK- 58 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 + + ++ +++H ++ + + +V EY + G L +++ + G VP Sbjct 59 --KLQESLMSEIIILRKINHPNIIRFIDMIEAPGKINLVLEYCKGGDLSMYIHKH-GSVP 115 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 A QLA+ L L + N++H ++ +N+LL+ + +K++D G Sbjct 116 EATAKHFMLQLAAGLQVLRDNNIIHRDLKPQNLLLS----TDDNDAALKIADFGFARSLQ 171 Query 768 SR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 R E ++APE + D W GA L ++ G P S + Sbjct 172 PRGLAETLCGSPLYMAPEIMQ--LQKYDAKADLWSVGAILFQLV-TGRTPFTGNSQIQLL 228 Query 825 HFYQRQHRLP-----EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLT 879 R L L + L P +R +F + + Sbjct 229 QNIIRSTELHFPADCRDLSTDCKDLCQKLLRRNPVERLTFEEFFHHPFLSDKQSYDFTRS 288 Query 880 VNPDSPASDPTVFHKRYLKKIRDLGE 905 +D + I ++ + Sbjct 289 RLDSRTMNDFHSSGSSPSRNIEEISQ 314 >sp|P50613|CDK7_HUMAN Cyclin-dependent kinase 7 OS=Homo sapiens OX=9606 GN=CDK7 PE=1 SV=1 Length=346 Score = 206 bits (523), Expect = 2e-57, Method: Composition-based stats. Identities = 69/305 (23%), Positives = 121/305 (40%), Gaps = 35/305 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYHE 957 LGEG F V Y + T ++VA+K +K + + G +EI +L+ L H Sbjct 17 FLGEGQFATV----YKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHP 72 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI--GLAQLLLFAQQICEGMAYLH 1015 +II + ++ LV +++ L + +S+ + + + +G+ YLH Sbjct 73 NIIGLLDAFGHKS--NISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRDL N+LLD + ++K+ DFGLAK+ + Y + ++ APE L Sbjct 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQ---VVTRWYRAPELLFG 186 Query 1076 -YKFYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIA--QGQMTVLRLTEL 1127 + D+W+ G L ELL DS T+ E +G + + L + Sbjct 187 ARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDY 246 Query 1128 LERGERLPRP-----DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182 + P ++ L++ + R T + + KY P Sbjct 247 VTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKM------KYFSNRPG 300 Query 1183 VFSVC 1187 C Sbjct 301 PTPGC 305 Score = 155 bits (392), Expect = 4e-40, Method: Composition-based stats. Identities = 46/264 (17%), Positives = 86/264 (33%), Gaps = 42/264 (16%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 +L LG+G VY+ RD+ V +K + H Sbjct 13 EKLDFLGEGQFATVYKA------------------------RDKNTNQIVAIKKIKLGHR 48 Query 650 DIALA-----FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 A L+ ++SH ++ + +V +++E L+V ++ Sbjct 49 SEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFME-TDLEVIIKDNSL 107 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + L YL ++H ++ N+LL G+ +KL+D G+ Sbjct 108 VLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGV-------LKLADFGLAK 160 Query 765 G----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 + +V + APE L GA +D W G L E+ Sbjct 161 SFGSPNRAYTHQVVTRWYRAPELLF-GARMYGVGVDMWAVGCILAELLLRVPFLPGDSDL 219 Query 821 SEKEHFYQRQHRLPEPSCPQLATL 844 + ++ E P + +L Sbjct 220 DQLTRIFETLGTPTEEQWPDMCSL 243 >sp|Q55GS4|CDK10_DICDI Probable cyclin-dependent kinase 10 OS=Dictyostelium discoideum OX=44689 GN=cdk10 PE=2 SV=1 Length=366 Score = 206 bits (524), Expect = 2e-57, Method: Composition-based stats. Identities = 71/288 (25%), Positives = 115/288 (40%), Gaps = 32/288 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYHE 957 +GEG +G VS + TG +VA+K +K G Q + G +EI IL+ + H Sbjct 12 SIGEGTYGIVS----KGRDKETGRIVALKKVK--IGQQDKDGIPLTSLREIQILKEIKHP 65 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLG--SLRDYLPRHSIGLAQLLLFAQQICEGMAYLH 1015 +I+ + LV EY+ SL D + + L+++ F Q+ + YLH Sbjct 66 NIVSLLEVVIGSTGDKIYLVFEYLEHDVASLIDNINK-PFKLSEIKCFLLQLLRAVEYLH 124 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + IHRDL N+L N+ +K+ DFGLA+ E +++ +PE L Sbjct 125 SHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPIESI---TPCMVTLWYRSPELLLG 181 Query 1076 -YKFYYASDVWSFGVTLYELLTHCD-----SSQSPPTKFLELIGIAQGQM--TVLRLTEL 1127 K+ A D+WS G ELL + + L+G Q+ L Sbjct 182 CQKYSTAVDLWSIGSIFGELLIGRPLITGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNF 241 Query 1128 LERGERLPRPDKCPCEV--------YHLMKNCWETEASFRPTFENLIP 1167 +P E+ + L+ + + R T + I Sbjct 242 KRLNNIPHQPYNNLRELVPTISDTAFDLLNQLLTYDPTKRITASDAIK 289 Score = 163 bits (413), Expect = 1e-42, Method: Composition-based stats. Identities = 50/265 (19%), Positives = 94/265 (35%), Gaps = 42/265 (16%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH 648 +L +G+GT V +G RD+ V LK + Sbjct 7 FEKLDSIGEGTYGIVSKG------------------------RDKETGRIVALKKVKIGQ 42 Query 649 HD---IALAFYETASLMSQVSHTHLAFVHGVCV--RGPENIMVTEYVEHGPLDVWLRRER 703 D I L ++ ++ H ++ + V + G + +V EY+EH + + Sbjct 43 QDKDGIPLTSLREIQILKEIKHPNIVSLLEVVIGSTGDKIYLVFEYLEH-DVASLIDNIN 101 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 ++ QL A+ YL + ++H ++ N+L G + +KL+D G+ Sbjct 102 KPFKLSEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLL-------YGNNGNLKLADFGLA 154 Query 764 LG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 S + + + +PE L G STA+D W G+ E+ + Sbjct 155 RKFGYPIESITPCMVTLWYRSPELLL-GCQKYSTAVDLWSIGSIFGELLIGRPLITGNNE 213 Query 820 PSEKEHFYQRQHRLPEPSCPQLATL 844 + + E P ++L Sbjct 214 VDQIMRIFNLLGEPNEQIWPGFSSL 238 >sp|Q6CJA8|HOG1_KLULA Mitogen-activated protein kinase HOG1 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=HOG1 PE=3 SV=1 Length=444 Score = 209 bits (531), Expect = 2e-57, Method: Composition-based stats. Identities = 65/318 (20%), Positives = 111/318 (35%), Gaps = 31/318 (10%) Query 876 DVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KA 934 + + +G G FG V T+ T + VA+K + K Sbjct 1 MSNEEFIRTQIFGTVFEITNRYTNLNPVGMGAFGLVC----SATDTLTSQPVAIKKIMKP 56 Query 935 DCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS 994 +E+ +L+ L HE++I + E + V E L L Sbjct 57 FSTSVLAKRTYRELKLLKHLRHENLICLEDIFLSPLED-IYFVTEL-QGTDLHRLLQTRP 114 Query 995 IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEY 1054 + + F QI G+ Y+H+ IHRDL N+L++ + +KI DFGLA+ Sbjct 115 LEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTG 174 Query 1055 YRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKF 1108 Y S ++ APE + K+ D+WS G E++ + Sbjct 175 Y------VSTRYYRAPEIMLTWQKYNVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSII 228 Query 1109 LELIGIAQGQMTVLRLTELLER-----GERLPRP-----DKCPCEVYHLMKNCWETEASF 1158 +L+G + +E + R P P + L++ + Sbjct 229 TDLLGSPPKDVIDTICSENTLKFVTSLPHRDPVPFSSRFQNLEPDAIDLLEKMLVFDPKK 288 Query 1159 RPTFENLI--PILKTVHE 1174 R T + + P L H+ Sbjct 289 RITAADALAHPYLSPYHD 306 Score = 137 bits (345), Expect = 4e-33, Method: Composition-based stats. Identities = 36/213 (17%), Positives = 70/213 (33%), Gaps = 18/213 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 V+E R G + D V +K ++ P +A Y Sbjct 12 FGTVFEITNRYTNLNPVGMGAF---GLVCSATDTLTSQPVAIKKIMKPFSTSVLAKRTYR 68 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H +L + + + + VTE + L L+ + + Sbjct 69 ELKLLKHLRHENLICLEDIFLSPLEDIYFVTEL-QGTDLHRLLQTR--PLEKQFVQYFLY 125 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + ++H ++ NIL+ + +K+ D G+ V Sbjct 126 QILRGLKYVHSAGVIHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 178 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + APE + + +D W G E+ Sbjct 179 RYYRAPE-IMLTWQKYNVEVDIWSAGCIFAEMI 210 >sp|P32490|MKK1_YEAST MAP kinase kinase MKK1/SSP32 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MKK1 PE=1 SV=1 Length=508 Score = 211 bits (536), Expect = 2e-57, Method: Composition-based stats. Identities = 67/271 (25%), Positives = 117/271 (43%), Gaps = 19/271 (7%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961 LGEG G VS ++ A+K + + P+++ +E+ R+ E+I++ Sbjct 227 LGEGAGGSVS----KCKLKNGSKIFALKVINTLNTDPEYQKQIFRELQFNRSFQSEYIVR 282 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLR----DYLPRH-SIGLAQLLLFAQQICEGMAYLHA 1016 Y G D S+ + MEY+ SL + L R I L A+ + G++YLH Sbjct 283 YYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHE 342 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + IHRD+ +N+LL+ + VK+ DFG++ G + F+ APE ++ Sbjct 343 KKVIHRDIKPQNILLNENGQVKLCDFGVS-----GEAVNSLATTFTGTSFYMAPERIQGQ 397 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 + SDVWS G+T+ E+ P + IA ++ + LT E + Sbjct 398 PYSVTSDVWSLGLTILEVANGKF----PCSSEKMAANIAPFELLMWILTFTPELKDEPES 453 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + C + ++ RP+ +I Sbjct 454 NIIWSPSFKSFIDYCLKKDSRERPSPRQMIN 484 Score = 172 bits (437), Expect = 2e-44, Method: Composition-based stats. Identities = 57/322 (18%), Positives = 104/322 (32%), Gaps = 56/322 (17%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + I L LG+G +V + +L+ LKV++ Sbjct 218 KDRIETLGILGEGAGGSVSKCKLKNGSKIF------------------------ALKVIN 253 Query 646 --PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPE--NIMVTEYVEHGPLDVW--- 698 + + + ++ +G+ + EY+ LD Sbjct 254 TLNTDPEYQKQIFRELQFNRSFQSEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKN 313 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 L G + +A+ + LSYL K ++H ++ +NILL G +KL Sbjct 314 LLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQ-------VKLC 366 Query 759 DPGVGLGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 D GV A++ ++APE + G S D W G T+LE+ +G+ P Sbjct 367 DFGVSGEAVNSLATTFTGTSFYMAPERIQG--QPYSVTSDVWSLGLTILEVA-NGKFPCS 423 Query 817 ------SRSPSEKEHFY-------QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 + +P E + + + P + CL + +RPS R ++ Sbjct 424 SEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMI 483 Query 864 RDLTRLQPHNLADVLTVNPDSP 885 + Sbjct 484 NHPWIKGQMKKNVNMEKFVRKC 505 >sp|Q42438|CDPK8_ARATH Calcium-dependent protein kinase 8 OS=Arabidopsis thaliana OX=3702 GN=CPK8 PE=1 SV=1 Length=533 Score = 211 bits (538), Expect = 2e-57, Method: Composition-based stats. Identities = 67/300 (22%), Positives = 111/300 (37%), Gaps = 33/300 (11%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEI 948 R++G G FG L T+ TGE A K++ K ++E+ Sbjct 51 HDISLMYDLGREVGRGEFGITYLC----TDIKTGEKYACKSISKKKLRTAVDIEDVRREV 106 Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006 +I++ + H +I+ K ED + ++ +VME G L D + R + Sbjct 107 EIMKHMPRHPNIVSLKDAFED--DDAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKT 164 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDS 1063 I E + H +HRDL N L N + +K DFGL+ G + + Sbjct 165 ILEVVQICHKHGVMHRDLKPENFLFANKKETSALKAIDFGLSVFFKPGEGFNEI----VG 220 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 ++ APE L+ + D+WS GV LY LL Q Sbjct 221 SPYYMAPEVLRRN-YGPEVDIWSAGVILYILLCGVPPF-----------WAETEQGVAQA 268 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183 + + +R P P L++ E + R + + L+ + +AP+V Sbjct 269 IIRSVIDFKRDPWPR-VSETAKDLVRKMLEPDPKKRLSAAQV---LEHSWIQNAKKAPNV 324 Score = 135 bits (341), Expect = 5e-32, Method: Composition-based stats. Identities = 49/327 (15%), Positives = 89/327 (27%), Gaps = 43/327 (13%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQL----SHLGQGTRTNVYEGRLR 609 +P SN + +I+ + +G+G Y Sbjct 18 KPKIKSNPFYSEAYTTNGSGTGFKLSVLKDPTGHDISLMYDLGREVGRGEFGITY--LCT 75 Query 610 VEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SHT 668 +G+ K + L D +M + H Sbjct 76 DIKTGEKYACKSISKKKLRTAVD-------------------IEDVRREVEIMKHMPRHP 116 Query 669 HLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK 728 ++ + +V E E G L + RGH V + + + Sbjct 117 NIVSLKDAFEDDDAVHIVMELCEGGELFDRI-VARGHYTERAAAAVMKTILEVVQICHKH 175 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECLP 785 ++H ++ N L + + +K D G+ + E E V ++APE L Sbjct 176 GVMHRDLKPENFL----FANKKETSALKAIDFGLSVFFKPGEGFNEIVGSPYYMAPEVLR 231 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-----QHRLPEPSCPQ 840 + +D W G L I G P + + R + Sbjct 232 ---RNYGPEVDIWSAGVILY-ILLCGVPPFWAETEQGVAQAIIRSVIDFKRDPWPRVSET 287 Query 841 LATLTSQCLTYEPTQRPSFRTILRDLT 867 L + L +P +R S +L Sbjct 288 AKDLVRKMLEPDPKKRLSAAQVLEHSW 314 >sp|Q9WVC6|SGK1_MOUSE Serine/threonine-protein kinase Sgk1 OS=Mus musculus OX=10090 GN=Sgk1 PE=1 SV=1 Length=431 Score = 208 bits (530), Expect = 2e-57, Method: Composition-based stats. Identities = 66/338 (20%), Positives = 117/338 (35%), Gaps = 29/338 (9%) Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885 F +++ ++A+ T C E + + + Sbjct 27 FMKQRRMGLNDFIQKIASNTYACKHAEVQSILKMSHPQEPELMNANPSPPPSPSQQINLG 86 Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSG 943 S ++ +G+G FGKV L + AVK L KA + Sbjct 87 PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEV----FYAVKVLQKKAILKKKEEKH 142 Query 944 WKQEID-ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLL 1001 E + +L+ + H ++ Q L V++Y+ G L +L R + Sbjct 143 IMSERNVLLKNVKHPFLVGLH--FSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRAR 200 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 +A +I + YLH+ + ++RDL N+LLD+ + + DFGL K E E+ Sbjct 201 FYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCK---ENIEHNGTTSTF 257 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 + APE L + + D W G LYE+L + T Sbjct 258 CGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPF--------------YSRNTA 303 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 +L + +L HL++ + + + R Sbjct 304 EMYDNILNKPLQLK--PNITNSARHLLEGLLQKDRTKR 339 Score = 162 bits (411), Expect = 1e-41, Method: Composition-based stats. Identities = 68/313 (22%), Positives = 110/313 (35%), Gaps = 45/313 (14%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEG 612 PQ E N + + +NL S + L +G+G+ V Sbjct 63 PQEPELMN-ANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKV--------- 112 Query 613 SGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETAS-LMSQVSHT 668 + R + +E+ +KVL + L+ V H Sbjct 113 ---------------LLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP 157 Query 669 HLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENK 728 L +H + V +Y+ G L L+RER + + A ++ASAL YL + Sbjct 158 FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARF-YAAEIASALGYLHSL 216 Query 729 NLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREERVERIPWLAPECL 784 N+V+ ++ NILL G I L+D G+ + + +LAPE L Sbjct 217 NIVYRDLKPENILLDSQG-------HIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVL 269 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPSCPQLAT 843 +D W GA L E+ G P SR+ +E + + +L Sbjct 270 H--KQPYDRTVDWWCLGAVLYEML-YGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARH 326 Query 844 LTSQCLTYEPTQR 856 L L + T+R Sbjct 327 LLEGLLQKDRTKR 339 >sp|P25323|MYLKA_DICDI Myosin light chain kinase A OS=Dictyostelium discoideum OX=44689 GN=mlkA PE=1 SV=2 Length=295 Score = 204 bits (518), Expect = 2e-57, Method: Composition-based stats. Identities = 74/291 (25%), Positives = 111/291 (38%), Gaps = 33/291 (11%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEI 948 ++ + +LG G F V L N T + A+K + K++ G + K E+ Sbjct 1 MTEVEKIYEFKEELGRGAFSIVYLG----ENKQTKQRYAIKVINKSELGKDYEKNLKMEV 56 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQI 1007 DIL+ + H +II K + L LVME V G L D + + S A ++I Sbjct 57 DILKKVNHPNIIALKELF--DTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKI 114 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLD---NDRLVKIGDFGLAKAVPEGHEYYRVREDGDSP 1064 + YLH + +HRDL N+LL N V I DFGL+K + + V + Sbjct 115 VSAVGYLHGLNIVHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQ----TLVMQTACGT 170 Query 1065 VFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRL 1124 + APE L + D+WS GV Y LL G Sbjct 171 PSYVAPEVLNATGYDKEVDMWSIGVITYILLCGFPPF--------------YGDTVPEIF 216 Query 1125 TELLERGERLP--RPDKCPCEVYHLMKNCWETEASFRPTFENLI--PILKT 1171 +++E P E + + S R N + P LK+ Sbjct 217 EQIMEANYEFPEEYWGGISKEAKDFIGKLLVVDVSKRLNATNALNHPWLKS 267 Score = 160 bits (406), Expect = 2e-42, Method: Composition-based stats. Identities = 49/255 (19%), Positives = 90/255 (35%), Gaps = 38/255 (15%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647 LG+G + VY G ++ + R +KV++ S Sbjct 9 EFKEELGRGAFSIVYLG------------------------ENKQTKQRYAIKVINKSEL 44 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 D ++ +V+H ++ + + + +V E V G L + E+G Sbjct 45 GKDYEKNLKMEVDILKKVNHPNIIALKELFDTPEKLYLVMELVTGGELFDKI-VEKGSYS 103 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL--- 764 A + +++ SA+ YL N+VH ++ N+LL + + ++D G+ Sbjct 104 EADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKS----KENHLEVAIADFGLSKIIG 159 Query 765 GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK- 823 L + ++APE L A +D W G I G P + E Sbjct 160 QTLVMQTACGTPSYVAPEVL--NATGYDKEVDMWSIGVITY-ILLCGFPPFYGDTVPEIF 216 Query 824 EHFYQRQHRLPEPSC 838 E + + PE Sbjct 217 EQIMEANYEFPEEYW 231 >sp|Q7SY52|STK10_DANRE Serine/threonine-protein kinase 10 OS=Danio rerio OX=7955 GN=stk10 PE=2 SV=1 Length=974 Score = 219 bits (558), Expect = 2e-57, Method: Composition-based stats. Identities = 75/306 (25%), Positives = 130/306 (42%), Gaps = 30/306 (10%) Query 869 LQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 + ++ V + I +LG+G FGKV Y N TG + A Sbjct 9 MFRLPTIEIKKKTKQYNHLQRDVNPNDMWEIIGELGDGAFGKV----YKAQNKETGVLAA 64 Query 929 VKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 K ++ + + EIDIL + H++I+K + S+ + E+ P G++ Sbjct 65 AKVIETK-SEEELEDYMVEIDILASCNHQYIVKLLDAFFFDNKLSIMI--EFCPGGAVDA 121 Query 989 YLPR--HSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAK 1046 + + Q+ + +Q+ E + YLH+ IHRDL A N+LL D +K+ DFG++ Sbjct 122 IMLELDRGLQEPQIRVICKQMLEALQYLHSMKIIHRDLKAGNILLTLDGDIKLADFGVS- 180 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPEC-----LKEYKFYYASDVWSFGVTLYELLTHCDSS 1101 + + + R+ +W APE +K+ + Y +D+WS G+TL EL + Sbjct 181 --AKNTKTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIEL-----AQ 233 Query 1102 QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPT 1161 PP L +L++ + G L +P K + +K + RPT Sbjct 234 IEPPHHEL------NPMRVLLKIAKSEPPG--LDQPSKWSMDFNDFLKKALDRHPETRPT 285 Query 1162 FENLIP 1167 L+ Sbjct 286 AAQLLE 291 Score = 177 bits (450), Expect = 5e-44, Method: Composition-based stats. Identities = 54/311 (17%), Positives = 99/311 (32%), Gaps = 45/311 (14%) Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 + + N Q + D EI LG G VY+ + + G Sbjct 18 KKKTKQYNHLQRDVNPNDMWEII--GELGDGAFGKVYKAQNKETG--------------- 60 Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVT 687 + KV++ + + +++ +H ++ + + ++ Sbjct 61 ---------VLAAAKVIETKSEEELEDYMVEIDILASCNHQYIVKLLDAFFFDNKLSIMI 111 Query 688 EYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGL 747 E+ G +D + + V+ +Q+ AL YL + ++H ++ NILL Sbjct 112 EFCPGGAVDAIMLELDRGLQEPQIRVICKQMLEALQYLHSMKIIHRDLKAGNILLT---- 167 Query 748 AEGTSPFIKLSDPGVGLGALS----REERVERIPWLAPECLP---GGANSLSTAMDKWGF 800 IKL+D GV R+ + W+APE + D W Sbjct 168 ---LDGDIKLADFGVSAKNTKTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSL 224 Query 801 GATLLEICFDGEAPLQSRSPSEKEHFYQR----QHRLPEPSCPQLATLTSQCLTYEPTQR 856 G TL+E+ E P +P + P + L P R Sbjct 225 GITLIELA-QIEPPHHELNPMRVLLKIAKSEPPGLDQPSKWSMDFNDFLKKALDRHPETR 283 Query 857 PSFRTILRDLT 867 P+ +L Sbjct 284 PTAAQLLEHPF 294 >sp|Q38873|CDPK7_ARATH Calcium-dependent protein kinase 7 OS=Arabidopsis thaliana OX=3702 GN=CPK7 PE=2 SV=1 Length=535 Score = 211 bits (538), Expect = 2e-57, Method: Composition-based stats. Identities = 69/300 (23%), Positives = 112/300 (37%), Gaps = 33/300 (11%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSGWKQEI 948 R++G G FG L T+ TGE A K++ K ++E+ Sbjct 53 HDISLQYDLGREVGRGEFGITYLC----TDKETGEKYACKSISKKKLRTAVDIEDVRREV 108 Query 949 DILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006 +I++ + H +++ K ED + ++ +VME G L D + R + Sbjct 109 EIMKHMPKHPNVVSLKDSFED--DDAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKT 166 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRL---VKIGDFGLAKAVPEGHEYYRVREDGDS 1063 I E + H Q +HRDL N L N + +K DFGL+ G ++ + Sbjct 167 IVEVVQICHKQGVMHRDLKPENFLFANKKETSALKAIDFGLSVFFKPGEQFNEI----VG 222 Query 1064 PVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLR 1123 ++ APE L+ + DVWS GV LY LL Q Sbjct 223 SPYYMAPEVLRRN-YGPEIDVWSAGVILYILLCGVPPF-----------WAETEQGVAQA 270 Query 1124 LTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183 + + +R P P L++ E + R T + L+ +AP+V Sbjct 271 IIRSVIDFKRDPWPR-VSDSAKDLVRKMLEPDPKKRLTAAQV---LEHTWILNAKKAPNV 326 Score = 135 bits (340), Expect = 7e-32, Method: Composition-based stats. Identities = 50/331 (15%), Positives = 95/331 (29%), Gaps = 44/331 (13%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQK-----EITQLSHLGQGTRTNVYEGRL 608 +P +N + R+ +LS + + +G+G Y Sbjct 19 KPKNKNNPFYSNEYATTDRSGAGFKLSVLKDPTGHDISLQYDLGREVGRGEFGITY--LC 76 Query 609 RVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SH 667 + +G+ K + L D +M + H Sbjct 77 TDKETGEKYACKSISKKKLRTAVD-------------------IEDVRREVEIMKHMPKH 117 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 ++ + +V E E G L + RGH V + + + Sbjct 118 PNVVSLKDSFEDDDAVHIVMELCEGGELFDRI-VARGHYTERAAAAVMKTIVEVVQICHK 176 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE---ERVERIPWLAPECL 784 + ++H ++ N L + + +K D G+ + E E V ++APE L Sbjct 177 QGVMHRDLKPENFL----FANKKETSALKAIDFGLSVFFKPGEQFNEIVGSPYYMAPEVL 232 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQR-----QHRLPEPSCP 839 + +D W G L I G P + + R + Sbjct 233 R---RNYGPEIDVWSAGVILY-ILLCGVPPFWAETEQGVAQAIIRSVIDFKRDPWPRVSD 288 Query 840 QLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 L + L +P +R + +L L Sbjct 289 SAKDLVRKMLEPDPKKRLTAAQVLEHTWILN 319 >sp|F4KA50|LRL22_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 2.2 OS=Arabidopsis thaliana OX=3702 GN=LRK10L-2.2 PE=3 SV=2 Length=624 Score = 213 bits (543), Expect = 2e-57, Method: Composition-based stats. Identities = 64/278 (23%), Positives = 114/278 (41%), Gaps = 25/278 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +G G FG V N G VAVK LK G + + E+ + H +I+ Sbjct 323 VGRGGFGTVYKG-----NLRDGRKVAVKILKDSNG--NCEDFINEVASISQTSHVNIVSL 375 Query 963 KGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLH---AQHY 1019 G C ++ +++ +V E++ GSL ++ ++ L A + G+ YLH + Sbjct 376 LGFCFEKSKRA--IVYEFLENGSLD---QSSNLDVSTLYGIALGVARGIEYLHFGCKKRI 430 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE--YK 1077 +H D+ +NVLLD + K+ DFGLAK E E D + + APE Sbjct 431 VHFDIKPQNVLLDENLKPKVADFGLAKLC-EKQESILSLLDTRGTIGYIAPELFSRVYGN 489 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE-----LIGIAQGQMTVLRLTELLERGE 1132 + SDV+S+G+ + E+ T + + + +LL G Sbjct 490 VSHKSDVYSYGMLVLEM-TGARNKERVQNADSNNSSAYFPDWIFKDLENGDYVKLLADGL 548 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + ++ + C + S RP+ ++ +++ Sbjct 549 TREE-EDIAKKMILVGLWCIQFRPSDRPSMNKVVGMME 585 Score = 199 bits (506), Expect = 2e-52, Method: Composition-based stats. Identities = 58/344 (17%), Positives = 121/344 (35%), Gaps = 66/344 (19%) Query 574 LNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDR 633 + + S+ ++ + + +G+G VY+G LR Sbjct 302 VTSRRYSYRQIKKITKSFTEVVGRGGFGTVYKGNLRDGR--------------------- 340 Query 634 GQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHG 693 +V +K+L S+ + F + +SQ SH ++ + G C + +V E++E+G Sbjct 341 ----KVAVKILKDSNGNC-EDFINEVASISQTSHVNIVSLLGFCFEKSKRAIVYEFLENG 395 Query 694 PLDVWLRRERGHVPMAWKMVVAQQLASALSYLE---NKNLVHGNVCGRNILLARLGLAEG 750 LD ++ ++ +A +A + YL K +VH ++ +N+LL Sbjct 396 SLDQ-----SSNLDVSTLYGIALGVARGIEYLHFGCKKRIVHFDIKPQNVLLDE------ 444 Query 751 TSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATL 804 + K++D G+ LS + I ++APE ++S D + +G + Sbjct 445 -NLKPKVADFGLAKLCEKQESILSLLDTRGTIGYIAPELFSRVYGNVSHKSDVYSYGMLV 503 Query 805 LEIC---------------FDGEAPLQSRSPSE----KEHFYQRQHRLPEPSCPQLATLT 845 LE+ P E + R E ++ + Sbjct 504 LEMTGARNKERVQNADSNNSSAYFPDWIFKDLENGDYVKLLADGLTREEEDIAKKMILVG 563 Query 846 SQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDP 889 C+ + P+ RPS ++ + + ++ Sbjct 564 LWCIQFRPSDRPSMNKVVGMMEGNLDSLDPPPKPLLHMPMQNNN 607 >sp|Q6FIU2|HOG1_CANGA Mitogen-activated protein kinase HOG1 OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=HOG1 PE=3 SV=1 Length=447 Score = 209 bits (531), Expect = 2e-57, Method: Composition-based stats. Identities = 61/283 (22%), Positives = 105/283 (37%), Gaps = 29/283 (10%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 +G G FG V T+ T + VA+K + K +E+ +L+ L HE++ Sbjct 27 NPVGMGAFGLVC----SATDTLTNQQVAIKKIMKPFATAVLAKRTYRELKLLKHLRHENL 82 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I + E + V E L L + + F QI G+ Y+H+ Sbjct 83 ICLQDIFLSPLED-IYFVTEL-QGTDLHRLLQTRPLEKQFVQYFHYQILRGLKYVHSAGV 140 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 141 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 194 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQMTVLRLTELLER--- 1130 D+WS G E++ + +L+G + +E + Sbjct 195 DVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPSDVIDTICSENTLKFVT 254 Query 1131 --GERLPRP-----DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 R P P + L++ + R T + + Sbjct 255 SLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADAL 297 Score = 134 bits (337), Expect = 5e-32, Method: Composition-based stats. Identities = 46/267 (17%), Positives = 85/267 (32%), Gaps = 21/267 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 V+E R G + D +V +K ++ P +A Y Sbjct 13 FGTVFEITNRYSDLNPVGMGAF---GLVCSATDTLTNQQVAIKKIMKPFATAVLAKRTYR 69 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H +L + + + + VTE + L L+ + + Sbjct 70 ELKLLKHLRHENLICLQDIFLSPLEDIYFVTEL-QGTDLHRLLQTR--PLEKQFVQYFHY 126 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 127 QILRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 179 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 + APE + +D W G E+ +G+ + F L Sbjct 180 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFAEMI-EGKPLFPGKDH--VHQFSIITDLLGS 235 Query 836 PSCPQLATLTSQCLTYEPTQRPSFRTI 862 P + T+ S+ T P I Sbjct 236 PPSDVIDTICSENTLKFVTSLPHRDPI 262 >sp|Q60823|AKT2_MOUSE RAC-beta serine/threonine-protein kinase OS=Mus musculus OX=10090 GN=Akt2 PE=1 SV=1 Length=481 Score = 210 bits (534), Expect = 2e-57, Method: Composition-based stats. Identities = 77/390 (20%), Positives = 128/390 (33%), Gaps = 61/390 (16%) Query 812 EAPLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQC--LTYEPTQRPSFRTILRDLTRL 869 EAP Q+ P +F + +L + P+ T +C T + + + Sbjct 43 EAPDQTLPP--LNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWM 100 Query 870 QPHNLADVLTVNPDSPASDPTVFH------------------------KRYLKKIRDLGE 905 + + ++ LG+ Sbjct 101 RAIQMVANSLKQRGPGEDAMDYKCGSPSDSSTSEMMEVAVNKARAKVTMNDFDYLKLLGK 160 Query 906 GHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHIIKYK 963 G FGKV L TG A+K L+ + + E +L+ H + K Sbjct 161 GTFGKVILV----REKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALK 216 Query 964 GCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHR 1022 Q L VMEY G L +L R + + +I + YLH++ ++R Sbjct 217 YAF--QTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRDVVYR 274 Query 1023 DLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYAS 1082 D+ N++LD D +KI DFGL K EG + + APE L++ + A Sbjct 275 DIKLENLMLDKDGHIKITDFGLCK---EGISDGATMKTFCGTPEYLAPEVLEDNDYGRAV 331 Query 1083 DVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPC 1142 D W GV +YE++ Q +L R PR Sbjct 332 DWWGLGVVMYEMMCGRLPF--------------YNQDHERLFELILMEEIRFPR--TLGP 375 Query 1143 EVYHLMKNCWETEASFR----PT-FENLIP 1167 E L+ + + R P+ + ++ Sbjct 376 EAKSLLAGLLKKDPKQRLGGGPSDAKEVME 405 Score = 165 bits (418), Expect = 3e-42, Method: Composition-based stats. Identities = 62/308 (20%), Positives = 110/308 (36%), Gaps = 46/308 (15%) Query 554 QPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGS 613 P ++S +M A R +V + L LG+GT V +R + + Sbjct 126 SPSDSSTSEMMEVAVNKAR---------AKVTMNDFDYLKLLGKGTFGKVI--LVREKAT 174 Query 614 GDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFV 673 G K+ ++ ++ + + + ++ H L + Sbjct 175 GRYYAMKILRKEVIIAKDEVAHTVT-------------------ESRVLQNTRHPFLTAL 215 Query 674 HGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHG 733 V EY G L L RER ++ SAL YL ++++V+ Sbjct 216 KYAFQTHDRLCFVMEYANGGELFFHLSRER-VFTEDRARFYGAEIVSALEYLHSRDVVYR 274 Query 734 NVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSR----EERVERIPWLAPECLPGGAN 789 ++ N++L + G IK++D G+ +S + +LAPE L N Sbjct 275 DIKLENLMLDKDG-------HIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLED--N 325 Query 790 SLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY-QRQHRLPEPSCPQLATLTSQC 848 A+D WG G + E+ G P ++ + R P P+ +L + Sbjct 326 DYGRAVDWWGLGVVMYEMMC-GRLPFYNQDHERLFELILMEEIRFPRTLGPEAKSLLAGL 384 Query 849 LTYEPTQR 856 L +P QR Sbjct 385 LKKDPKQR 392 >sp|Q9C9M7|CDKD2_ARATH Cyclin-dependent kinase D-2 OS=Arabidopsis thaliana OX=3702 GN=CDKD-2 PE=1 SV=1 Length=348 Score = 205 bits (522), Expect = 2e-57, Method: Composition-based stats. Identities = 69/298 (23%), Positives = 123/298 (41%), Gaps = 36/298 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRS-GWKQEIDILRTLYHEHIIK 961 LGEG +G V Y T+ TG+ VAVK ++ + + +EI +L+ L H HI++ Sbjct 19 LGEGTYGVV----YKATDTKTGKTVAVKKIRLGNQKEGVNFTALREIKLLKELNHPHIVE 74 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLA--QLLLFAQQICEGMAYLHAQHY 1019 G SL LV EY+ L + +I L+ + + +G+AY H + Sbjct 75 LIDAFPHDG--SLHLVFEYMQ-TDLEAVIRDRNIFLSPGDIKSYMLMTLKGLAYCHKKWV 131 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRD+ N+L+ + L+K+ DFGLA+ + + + ++ APE L ++ Sbjct 132 LHRDMKPNNLLIGENGLLKLADFGLARLFGSPNRRFTHQVFA---TWYRAPELLFGSRQY 188 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIG---------IAQGQMTVLRLTELLE 1129 DVW+ G ELL P + ++ +G + ++ L + +E Sbjct 189 GAGVDVWAAGCIFAELLLRRPFL--PGSTEIDQLGKIFQAFGTPVPSQWSDMIYLPDYME 246 Query 1130 RGERLPRP-----DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182 P + L+ + + R T + + +Y +PS Sbjct 247 FSYTPAPPLRTIFPMASDDALDLLAKMFIYDPRQRITIQQ------ALDHRYFSSSPS 298 Score = 150 bits (380), Expect = 2e-38, Method: Composition-based stats. Identities = 45/255 (18%), Positives = 81/255 (32%), Gaps = 40/255 (16%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALA 654 LG+GT VY+ D V +K + + + Sbjct 19 LGEGTYGVVYKA------------------------TDTKTGKTVAVKKIRLGNQKEGVN 54 Query 655 F--YETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 F L+ +++H H+ + +V EY++ L+ +R + Sbjct 55 FTALREIKLLKELNHPHIVELIDAFPHDGSLHLVFEYMQ-TDLEAVIRDRNIFLSPGDIK 113 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER 772 L+Y K ++H ++ N+L+ GL +KL+D G+ S R Sbjct 114 SYMLMTLKGLAYCHKKWVLHRDMKPNNLLIGENGL-------LKLADFGLARLFGSPNRR 166 Query 773 ----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA-PLQSRSPSEKEHFY 827 V + APE L G+ +D W G E+ P + + F Sbjct 167 FTHQVFATWYRAPELLF-GSRQYGAGVDVWAAGCIFAELLLRRPFLPGSTEIDQLGKIFQ 225 Query 828 QRQHRLPEPSCPQLA 842 +P + Sbjct 226 AFGTPVPSQWSDMIY 240 >sp|Q9WUT3|KS6A2_MOUSE Ribosomal protein S6 kinase alpha-2 OS=Mus musculus OX=10090 GN=Rps6ka2 PE=1 SV=1 Length=733 Score = 216 bits (549), Expect = 2e-57, Method: Composition-based stats. Identities = 68/259 (26%), Positives = 109/259 (42%), Gaps = 24/259 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961 LG+G +GKV L T G++ A+K LK + R K E DIL + H I+K Sbjct 65 LGQGSYGKVFLVR-KVTGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVK 123 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020 Q E L L+++++ G L L + + + ++ + +LH I Sbjct 124 LHYAF--QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHGLGII 181 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 +RDL N+LLD + +KI DFGL+K E ++ + + + APE + Sbjct 182 YRDLKPENILLDEEGHIKITDFGLSK---EATDHDKRAYSFCGTIEYMAPEVVNRRGHTQ 238 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ++D WSFGV ++E+LT Q K T L +L P Sbjct 239 SADWWSFGVLMFEMLTGSLPFQGKDRKE----------------TMALILKAKLGMPQFL 282 Query 1141 PCEVYHLMKNCWETEASFR 1159 E L++ ++ R Sbjct 283 SAEAQSLLRALFKRNPCNR 301 Score = 198 bits (504), Expect = 1e-51, Method: Composition-based stats. Identities = 65/307 (21%), Positives = 104/307 (34%), Gaps = 37/307 (12%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 ++ + + D+G G + + T+ AVK Sbjct 389 QQDVPKAPIHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATD----AEYAVK 444 Query 931 ALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD- 988 + + +EI+IL H +II K +D K + LVME + G L D Sbjct 445 IIDKS-----KRDPSEEIEILLRYGQHPNIITLKDVYDDG--KYVYLVMELMRGGELLDR 497 Query 989 YLPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVL-LDNDRL---VKIGDFGL 1044 L + + I M YLH+Q +HRDL N+L +D ++I DFG Sbjct 498 ILRQRCFSEREASDVLYTIARTMDYLHSQGVVHRDLKPSNILYMDESGNPESIRICDFGF 557 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS--- 1101 AK + + + APE LK + A DVWS G+ LY +L Sbjct 558 AKQLRAENGLLMT---PCYTANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANG 614 Query 1102 -QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 P + L IG + ++ D ++ + R Sbjct 615 PDDTPEEILARIGSGKYALSGGNW-------------DSISDAAKDVVSKMLHVDPQQRL 661 Query 1161 TFENLIP 1167 T ++ Sbjct 662 TAVQVLK 668 Score = 174 bits (440), Expect = 2e-43, Method: Composition-based stats. Identities = 59/283 (21%), Positives = 106/283 (37%), Gaps = 39/283 (14%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 F + D + L LGQG+ V+ R V G D GQ Sbjct 51 FEKADPSQFELLKVLGQGSYGKVFLVR-------------------KVTGSDAGQ--LYA 89 Query 641 LKVLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +KVL + + ++++V+H + +H + ++ +++ G L Sbjct 90 MKVLKKATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTR 149 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 L +E K +A +LA AL +L +++ ++ NILL G IK++ Sbjct 150 LSKEVMFTEEDVKFYLA-ELALALDHLHGLGIIYRDLKPENILLDEEG-------HIKIT 201 Query 759 DPGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 D G+ A ++R I ++APE + + + D W FG + E+ G P Sbjct 202 DFGLSKEATDHDKRAYSFCGTIEYMAPEVV--NRRGHTQSADWWSFGVLMFEML-TGSLP 258 Query 815 LQSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQR 856 Q + E + +P+ + +L P R Sbjct 259 FQGKDRKETMALILKAKLGMPQFLSAEAQSLLRALFKRNPCNR 301 Score = 155 bits (392), Expect = 1e-37, Method: Composition-based stats. Identities = 48/267 (18%), Positives = 87/267 (33%), Gaps = 24/267 (9%) Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690 + + +K++D S D + E ++ + H ++ + V G +V E + Sbjct 434 HKATDAEYAVKIIDKSKRDPS----EEIEILLRYGQHPNIITLKDVYDDGKYVYLVMELM 489 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L + R+R V +A + YL ++ +VH ++ NIL G Sbjct 490 RGGELLDRILRQRC-FSEREASDVLYTIARTMDYLHSQGVVHRDLKPSNIL---YMDESG 545 Query 751 TSPFIKLSDPGVGLGALSREERVERIPWL----APECLPGGANSLSTAMDKWGFGATLLE 806 I++ D G + + + APE L A D W G L Sbjct 546 NPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLK--RQGYDAACDVWSLGILLYT 603 Query 807 ICFDGEAPL---QSRSPSEKEHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPS 858 + G P +P E + + S+ L +P QR + Sbjct 604 MLA-GFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPQQRLT 662 Query 859 FRTILRDLTRLQPHNLADVLTVNPDSP 885 +L+ + L+ D Sbjct 663 AVQVLKHPWIVNREYLSQNQLSRQDVH 689 >sp|Q05006|CDC22_MEDSA Cell division control protein 2 homolog 2 OS=Medicago sativa OX=3879 GN=CDC2B PE=2 SV=1 Length=294 Score = 203 bits (517), Expect = 2e-57, Method: Composition-based stats. Identities = 74/291 (25%), Positives = 126/291 (43%), Gaps = 33/291 (11%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ Sbjct 1 MEQYEKVEKIGEGTYGVV----YKARDRATNETIALKKIRLEQEDEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009 + H +I++ + EK L LV EY+ L L+ ++ P + Q+ +F QI Sbjct 57 EMQHRNIVRLQDVV--HSEKRLYLVFEYLDL-DLKKFMDSSPEFAKDQRQIKMFLYQILC 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 G+AY H+ +HRDL +N+L+D VK+ DFGLA+A R +++ Sbjct 114 GIAYCHSHRVLHRDLKPQNLLIDRSSNAVKLADFGLARAFGIP---VRTFTHEVVTLWYR 170 Query 1069 APECLKEYK-FYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVL 1122 APE L + + DVWS G E++ DS K + G + T Sbjct 171 APEILLGSRHYSTPVDVWSVGCIFAEMINQRPLFPGDSEIDELFKIFRITGTPNEE-TWP 229 Query 1123 RLTELLERGERLPR----------PDKCPCEVYHLMKNCWETEASFRPTFE 1163 +T L + P+ P+ P + L+ + + + R T Sbjct 230 GVTSLPDFKSAFPKWPAKDLATQVPNLEPAGL-DLLSSTCRLDPTRRITAR 279 Score = 167 bits (423), Expect = 8e-45, Method: Composition-based stats. Identities = 46/266 (17%), Positives = 96/266 (36%), Gaps = 39/266 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 ++ ++ +G+GT VY+ RDR + LK Sbjct 1 MEQYEKVEKIGEGTYGVVYKA------------------------RDRATNETIALKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 L+ + SL+ ++ H ++ + V +V EY++ L ++ Sbjct 37 LEQEDEGVPSTAIREISLLKEMQHRNIVRLQDVVHSEKRLYLVFEYLDL-DLKKFMDSSP 95 Query 704 GHVPMAWKMVV-AQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 ++ + Q+ ++Y + ++H ++ +N+L+ R +S +KL+D G+ Sbjct 96 EFAKDQRQIKMFLYQILCGIAYCHSHRVLHRDLKPQNLLIDR------SSNAVKLADFGL 149 Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + + APE L G+ ST +D W G E+ Sbjct 150 ARAFGIPVRTFTHEVVTLWYRAPEILL-GSRHYSTPVDVWSVGCIFAEMINQRPLFPGDS 208 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844 E ++ E + P + +L Sbjct 209 EIDELFKIFRITGTPNEETWPGVTSL 234 >sp|P24100|CDKA1_ARATH Cyclin-dependent kinase A-1 OS=Arabidopsis thaliana OX=3702 GN=CDKA-1 PE=1 SV=1 Length=294 Score = 203 bits (517), Expect = 2e-57, Method: Composition-based stats. Identities = 71/286 (25%), Positives = 122/286 (43%), Gaps = 31/286 (11%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ Sbjct 1 MDQYEKVEKIGEGTYGVV----YKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009 + H +I+K + EK L LV EY+ L L+ ++ P S L + + QI Sbjct 57 EMQHSNIVKLQDVV--HSEKRLYLVFEYLDL-DLKKHMDSTPDFSKDLHMIKTYLYQILR 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 G+AY H+ +HRDL +N+L+D +K+ DFGLA+A R +++ Sbjct 114 GIAYCHSHRVLHRDLKPQNLLIDRRTNSLKLADFGLARAFGIP---VRTFTHEVVTLWYR 170 Query 1069 APECLKE-YKFYYASDVWSFGVTLYELLTHC-----DSSQSPPTKFLELIGIAQGQMTVL 1122 APE L + + D+WS G E+++ DS K ++G T Sbjct 171 APEILLGSHHYSTPVDIWSVGCIFAEMISQKPLFPGDSEIDQLFKIFRIMGTPYED-TWR 229 Query 1123 RLTELLERGERLP--RP-------DKCPCEVYHLMKNCWETEASFR 1159 +T L + P +P + L+ + + R Sbjct 230 GVTSLPDYKSAFPKWKPTDLETFVPNLDPDGVDLLSKMLLMDPTKR 275 Score = 159 bits (402), Expect = 6e-42, Method: Composition-based stats. Identities = 42/266 (16%), Positives = 92/266 (35%), Gaps = 39/266 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 + ++ +G+GT VY+ RD+ + LK Sbjct 1 MDQYEKVEKIGEGTYGVVYKA------------------------RDKVTNETIALKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702 L+ + SL+ ++ H+++ + V +V EY++ L + Sbjct 37 LEQEDEGVPSTAIREISLLKEMQHSNIVKLQDVVHSEKRLYLVFEYLDL-DLKKHMDSTP 95 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + Q+ ++Y + ++H ++ +N+L+ R + +KL+D G+ Sbjct 96 DFSKDLHMIKTYLYQILRGIAYCHSHRVLHRDLKPQNLLIDRR------TNSLKLADFGL 149 Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + + APE L G++ ST +D W G E+ Sbjct 150 ARAFGIPVRTFTHEVVTLWYRAPEILL-GSHHYSTPVDIWSVGCIFAEMISQKPLFPGDS 208 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ E + + +L Sbjct 209 EIDQLFKIFRIMGTPYEDTWRGVTSL 234 >sp|Q9M6A7|CLV1B_SOYBN Leucine-rich repeat receptor-like kinase protein CLV1B OS=Glycine max OX=3847 GN=CLV1B PE=2 SV=1 Length=987 Score = 219 bits (558), Expect = 2e-57, Method: Composition-based stats. Identities = 81/324 (25%), Positives = 133/324 (41%), Gaps = 25/324 (8%) Query 862 ILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTND 921 + + R + NLA + + LK+ +G+G G V + Sbjct 661 VTVYMMRRRKMNLAKTWKLTAFQRLNFKAEDVVECLKEENIIGKGGAGIVYRG-----SM 715 Query 922 GTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYV 981 G VA+K L ++ G+K EI+ L + H +I++ G ++ E +L L EY+ Sbjct 716 PNGTDVAIKRLVGAGSGRNDYGFKAEIETLGKIRHRNIMRLLGYVSNK-ETNLLL-YEYM 773 Query 982 PLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH---YIHRDLAARNVLLDNDR 1035 P GSL ++L + A + +G+ YLH IHRD+ + N+LLD D Sbjct 774 PNGSLGEWLHGAKGGHLKWEMRYKIAVEAAKGLCYLHHDCSPLIIHRDVKSNNILLDGDL 833 Query 1036 LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELL 1095 + DFGLAK + + + S + APE K SDV+SFGV L EL+ Sbjct 834 EAHVADFGLAKFLYDPGASQSMSSIAGS-YGYIAPEYAYTLKVDEKSDVYSFGVVLLELI 892 Query 1096 THCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL----PRPDKCPCE----VYHL 1147 ++++G T L L + + L PR P ++++ Sbjct 893 IGRKPVGE-FGDGVDIVGWVN--KTRLELAQPSDAALVLAVVDPRLSGYPLTSVIYMFNI 949 Query 1148 MKNCWETEASFRPTFENLIPILKT 1171 C + RPT ++ +L Sbjct 950 AMMCVKEMGPARPTMREVVHMLSE 973 Score = 187 bits (476), Expect = 3e-47, Method: Composition-based stats. Identities = 52/327 (16%), Positives = 93/327 (28%), Gaps = 47/327 (14%) Query 589 ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVL-DPS 647 + + + +G+G VY G V +K L Sbjct 696 LKEENIIGKGGAGIVYRG-------------------------SMPNGTDVAIKRLVGAG 730 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHV 706 F + ++ H ++ + G N+++ EY+ +G L WL + GH+ Sbjct 731 SGRNDYGFKAEIETLGKIRHRNIMRLLGYVSNKETNLLLYEYMPNGSLGEWLHGAKGGHL 790 Query 707 PMAWKMVVAQQLASALSYLENKN---LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + +A + A L YL + ++H +V NILL A ++D G+ Sbjct 791 KWEMRYKIAVEAAKGLCYLHHDCSPLIIHRDVKSNNILLDGDLEAH-------VADFGLA 843 Query 764 LGAL------SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 S ++APE + D + FG LLE+ G P Sbjct 844 KFLYDPGASQSMSSIAGSYGYIAPEYA--YTLKVDEKSDVYSFGVVLLELII-GRKP-VG 899 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADV 877 + E + P A L + + P I + Sbjct 900 EFGDGVDIVGWVNKTRLELAQPSDAALVLAVVDPRLSGYPLTSVIYMFNIAMMCVKEMGP 959 Query 878 LTVNPDSPASDPTVFHKRYLKKIRDLG 904 + + Sbjct 960 ARPTMREVVHMLSEPPHSATHTHNLIN 986 >sp|Q92241|PHO85_KLULA Negative regulator of the PHO system OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=PHO85 PE=3 SV=2 Length=304 Score = 204 bits (518), Expect = 2e-57, Method: Composition-based stats. Identities = 64/300 (21%), Positives = 123/300 (41%), Gaps = 36/300 (12%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRT 953 K++ +G G + V Y N TG VA+K +K D S +EI +++ Sbjct 4 PSQFKQLEKVGNGTYATV----YKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKE 59 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-------IGLAQLLLFAQQ 1006 L H++I++ E L LV E++ L+ ++ + + + + F Q Sbjct 60 LKHDNIVRLFDVI--HTENKLTLVFEFMDN-DLKKFMDNRNKGNSHKGLEMDLVKYFQWQ 116 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 + +G+A+ H +HRDL +N+L++N +K+GDFGLA+A ++ Sbjct 117 LLQGVAFCHENRILHRDLKPQNLLINNRGQLKLGDFGLARAFGIP---VNTFSSEVVTLW 173 Query 1067 WYAPECLKEYK-FYYASDVWSFGVTLYELLTHCDSSQ-SPPTKFLELIGIAQGQMTVLRL 1124 + AP+ L + + + D+WS G L E++ S + L+LI G Sbjct 174 YRAPDVLMGSRNYCTSIDIWSCGCILAEMIMGKPLFPGSNDEEQLKLIFDTMGTPVEQTW 233 Query 1125 TELLE-RGERLPRPDKCPCEVYHLMKN----------------CWETEASFRPTFENLIP 1167 ++ + P P ++ L++N + R + ++ + Sbjct 234 PQVTQLAKYNPLLPPHMPRDLKQLLQNNTEEVLDDNVVDLLHGLLQLNPDARLSAKDALN 293 Score = 167 bits (424), Expect = 8e-45, Method: Composition-based stats. Identities = 48/273 (18%), Positives = 95/273 (35%), Gaps = 43/273 (16%) Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 V + QL +G GT VY+G + G + V LK Sbjct 2 VAPSQFKQLEKVGNGTYATVYKGLNKTTG------------------------VYVALKE 37 Query 644 LDPSHHDIA-LAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRE 702 + + SLM ++ H ++ + V + +V E++++ L ++ Sbjct 38 VKLDSEEGTPSTAIREISLMKELKHDNIVRLFDVIHTENKLTLVFEFMDN-DLKKFMDNR 96 Query 703 R-----GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKL 757 + M QL +++ ++H ++ +N+L+ G +KL Sbjct 97 NKGNSHKGLEMDLVKYFQWQLLQGVAFCHENRILHRDLKPQNLLINNRGQ-------LKL 149 Query 758 SDPGVGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEA 813 D G+ + V + + AP+ L G+ + T++D W G L E+ Sbjct 150 GDFGLARAFGIPVNTFSSEVVTLWYRAPDVLM-GSRNYCTSIDIWSCGCILAEMIMGKPL 208 Query 814 PLQSRSPSEKEHFYQRQHRLPEPSCPQLATLTS 846 S + + + E + PQ+ L Sbjct 209 FPGSNDEEQLKLIFDTMGTPVEQTWPQVTQLAK 241 >sp|A3LN91|HOG1_PICST Mitogen-activated protein kinase HOG1 OS=Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) OX=322104 GN=HOG1 PE=3 SV=2 Length=385 Score = 206 bits (525), Expect = 2e-57, Method: Composition-based stats. Identities = 65/289 (22%), Positives = 106/289 (37%), Gaps = 32/289 (11%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRT 953 + +G G FG V + TG+ VAVK + K +E+ +L+ Sbjct 21 NRYTDLNPVGMGAFGLVC----SAVDKLTGQNVAVKKIMKPFSTSVLAKRTYRELKLLKH 76 Query 954 LYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAY 1013 L HE++I E + V E L L + + F QI G+ Y Sbjct 77 LKHENLITLDDIFLSPLED-IYFVNEL-QGTDLHRLLTSRPLEKQFIQYFTYQILRGLKY 134 Query 1014 LHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL 1073 +H+ IHRDL N+L++ + +KI DFGLA+ Y S ++ APE + Sbjct 135 IHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIM 188 Query 1074 KE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGIAQGQM-------T 1120 K+ D+WS G L E++ + EL+G + Sbjct 189 LTWQKYDTEVDLWSVGCILAEMIEGKPLFPGKDHVHQFSIITELLGSPPPDVIDTICSEN 248 Query 1121 VLRLTELLERGERLPRPDKCP------CEVYHLMKNCWETEASFRPTFE 1163 LR + L + +P ++ E L+ + R + Sbjct 249 TLRFVQSLPHRDPIPFNERFAQCTHVEPEAIDLLAKMLIFDPKKRISAA 297 Score = 135 bits (341), Expect = 6e-33, Method: Composition-based stats. Identities = 47/324 (15%), Positives = 89/324 (27%), Gaps = 38/324 (12%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 V+E R G + D+ V +K ++ P +A Y Sbjct 13 FGTVFEITNRYTDLNPVGMGAF---GLVCSAVDKLTGQNVAVKKIMKPFSTSVLAKRTYR 69 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H +L + + + + V E + L L + + Sbjct 70 ELKLLKHLKHENLITLDDIFLSPLEDIYFVNEL-QGTDLHRLLTSR--PLEKQFIQYFTY 126 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + ++H ++ NIL+ + +K+ D G+ V Sbjct 127 QILRGLKYIHSAGVIHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 179 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC--------------------FDGEAPL 815 + APE + T +D W G L E+ G P Sbjct 180 RYYRAPE-IMLTWQKYDTEVDLWSVGCILAEMIEGKPLFPGKDHVHQFSIITELLGSPPP 238 Query 816 QSRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLA 875 E+ + LP +QC EP +L + + + Sbjct 239 DVIDTICSENTLRFVQSLPHRDPIPFNERFAQCTHVEPEAIDLLAKMLIFDPKKRISAAS 298 Query 876 DVLTVNPDSPASDPTVFHKRYLKK 899 + + Sbjct 299 ALTHPYMEPYHDPTDEPICETKFD 322 >sp|Q5GIG6|TNI3K_MOUSE Serine/threonine-protein kinase TNNI3K OS=Mus musculus OX=10090 GN=Tnni3k PE=2 SV=4 Length=834 Score = 217 bits (553), Expect = 2e-57, Method: Composition-based stats. Identities = 72/327 (22%), Positives = 129/327 (39%), Gaps = 30/327 (9%) Query 852 EPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKV 911 +P S+ ++ L +++ + + ++ +G G FGKV Sbjct 417 QPGGDGSYVSVPSPLGKIKSMTKEKADVLLLRAELPSRFHLQLSEIEFHEIIGSGSFGKV 476 Query 912 SLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQ 969 ++VA+K +A+ C + +E+ IL L H ++++ G C D Sbjct 477 YKG------RCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVVQFVGACLD- 529 Query 970 GEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLLLFAQQICEGMAYLHA--QHYIHRDLA 1025 +V +Y+ GSL L + L L+ A + +GM YLH+ Q IHRDL Sbjct 530 DPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHSLTQPIIHRDLN 589 Query 1026 ARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKFYYASDV 1084 + N+LL D + DFG ++ + E ++ G+ + W APE + ++ +DV Sbjct 590 SHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGN--LRWMAPEVFTQCTRYTIKADV 647 Query 1085 WSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEV 1144 +S+ + L+ELLT ++ R P P + Sbjct 648 FSYALCLWELLTGEIPFAH--------------LKPAAAAADMAYHHIRPPIGYSIPKPI 693 Query 1145 YHLMKNCWETEASFRPTFENLIPILKT 1171 L+ W RP F ++ L+ Sbjct 694 SSLLMRGWNACPEGRPEFSEVVRKLEE 720 Score = 209 bits (531), Expect = 2e-54, Method: Composition-based stats. Identities = 62/331 (19%), Positives = 125/331 (38%), Gaps = 59/331 (18%) Query 556 GETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGD 615 E ++++++R S L LS++ FH + +G G+ VY+GR R + Sbjct 439 KEKADVLLLRAELPSRFHLQLSEIEFHEI----------IGSGSFGKVYKGRCRNK---- 484 Query 616 PEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETASLMSQVSHTHLAF 672 V +K + F S++ Q++H + Sbjct 485 ----------------------IVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVVQ 522 Query 673 VHGVCVRGP-ENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN--KN 729 G C+ P + +VT+Y+ G L L ++ + + K+++A +A + YL + + Sbjct 523 FVGACLDDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHSLTQP 582 Query 730 LVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-----GALSREERVERIPWLAPECL 784 ++H ++ NILL G A ++D G + ++ + W+APE Sbjct 583 IIHRDLNSHNILLYEDGHAV-------VADFGESRFLQSLDEDNMTKQPGNLRWMAPEVF 635 Query 785 PGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH---FYQRQHRLPEPSCPQL 841 + D + + L E+ GE P P+ ++ + + + Sbjct 636 TQCTR-YTIKADVFSYALCLWELL-TGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPI 693 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPH 872 ++L + P RP F ++R L + Sbjct 694 SSLLMRGWNACPEGRPEFSEVVRKLEECLCN 724 >sp|Q54N73|7TMK1_DICDI Seven transmembrane domain-containing tyrosine-protein kinase 1 OS=Dictyostelium discoideum OX=44689 GN=7tmk1 PE=3 SV=1 Length=691 Score = 215 bits (547), Expect = 2e-57, Method: Composition-based stats. Identities = 71/295 (24%), Positives = 124/295 (42%), Gaps = 40/295 (14%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-----GPQHRSGW 944 K + +GEG+FG+V + G +VAVK L + G + + + Sbjct 356 FYIRFNEFKFGQVIGEGYFGEVRKAVWK------GAVVAVKILHRNSFRNTDGNKEENVF 409 Query 945 KQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQ----L 1000 +E+ IL L H +++++ G C + +V EY+ GSL L + Q Sbjct 410 LKEVAILSILRHPNVLQFLGVCSETNLNG--IVTEYMGGGSLDRLLTDRYFLIKQNPILA 467 Query 1001 LLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLV-KIGDFGLAKAVPEGHEYYR 1056 A I GM YLH +HRDL+ +N+LLD + K+ DFGL+K E Sbjct 468 WNMAISIARGMFYLHDWKPNPILHRDLSTKNILLDESLTIAKVADFGLSK------EQGF 521 Query 1057 VREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQS-PPTKFLELIGIA 1115 + + APE + +DV+SFG+ ++ ++T +Q+ P K L Sbjct 522 EMTSTVGHLCYQAPEVFIGELYTPKADVYSFGLLVWCIITGEQPNQNLQPLKMAHLAAYE 581 Query 1116 QGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + + + + + + L++ CW+ RP+F ++ L+ Sbjct 582 NYRPPMPQPMDPMWEN------------LGKLIEMCWKKSPEERPSFSFILDFLE 624 Score = 207 bits (528), Expect = 6e-55, Method: Composition-based stats. Identities = 64/305 (21%), Positives = 108/305 (35%), Gaps = 57/305 (19%) Query 578 QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQEL 637 QLS + E +G+G V + + Sbjct 352 QLSAFYIRFNEFKFGQVIGEGYFGEVRKAVWKG--------------------------A 385 Query 638 RVVLKVLDPSH---HDIALA---FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVE 691 V +K+L + D F + +++S + H ++ GVC N +VTEY+ Sbjct 386 VVAVKILHRNSFRNTDGNKEENVFLKEVAILSILRHPNVLQFLGVCSETNLNGIVTEYMG 445 Query 692 HGPLDVWLRRE----RGHVPMAWKMVVAQQLASALSYLEN---KNLVHGNVCGRNILLAR 744 G LD L + + +AW M ++ +A + YL + ++H ++ +NILL Sbjct 446 GGSLDRLLTDRYFLIKQNPILAWNMAIS--IARGMFYLHDWKPNPILHRDLSTKNILLDE 503 Query 745 LGLAEGTSPFIKLSDPGVGL-GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGAT 803 K++D G+ V + + APE G + D + FG Sbjct 504 SLT------IAKVADFGLSKEQGFEMTSTVGHLCYQAPEVFIGEL--YTPKADVYSFGLL 555 Query 804 LLEICFDGEAPLQSRSPSEKEHFYQRQHR------LPEPSCPQLATLTSQCLTYEPTQRP 857 + GE P Q+ P + H ++ +P L L C P +RP Sbjct 556 VW-CIITGEQPNQNLQPLKMAHLAAYENYRPPMPQPMDPMWENLGKLIEMCWKKSPEERP 614 Query 858 SFRTI 862 SF I Sbjct 615 SFSFI 619 >sp|O00141|SGK1_HUMAN Serine/threonine-protein kinase Sgk1 OS=Homo sapiens OX=9606 GN=SGK1 PE=1 SV=2 Length=431 Score = 208 bits (529), Expect = 2e-57, Method: Composition-based stats. Identities = 65/338 (19%), Positives = 116/338 (34%), Gaps = 29/338 (9%) Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885 F +++ ++A + C E + + + Sbjct 27 FMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNANPSPPPSPSQQINLG 86 Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL--KADCGPQHRSG 943 S ++ +G+G FGKV L + AVK L KA + Sbjct 87 PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEV----FYAVKVLQKKAILKKKEEKH 142 Query 944 WKQEID-ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLL 1001 E + +L+ + H ++ Q L V++Y+ G L +L R + Sbjct 143 IMSERNVLLKNVKHPFLVGLH--FSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRAR 200 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG 1061 +A +I + YLH+ + ++RDL N+LLD+ + + DFGL K E E+ Sbjct 201 FYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCK---ENIEHNSTTSTF 257 Query 1062 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV 1121 + APE L + + D W G LYE+L + T Sbjct 258 CGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPF--------------YSRNTA 303 Query 1122 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 +L + +L HL++ + + + R Sbjct 304 EMYDNILNKPLQLK--PNITNSARHLLEGLLQKDRTKR 339 Score = 163 bits (412), Expect = 6e-42, Method: Composition-based stats. Identities = 68/314 (22%), Positives = 110/314 (35%), Gaps = 45/314 (14%) Query 552 LPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 PQ E N + + +NL S + L +G+G+ V Sbjct 62 QPQEPELMN-ANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKV-------- 112 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS---HHDIALAFYETAS-LMSQVSH 667 + R + +E+ +KVL + L+ V H Sbjct 113 ----------------LLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156 Query 668 THLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLEN 727 L +H + V +Y+ G L L+RER + + A ++ASAL YL + Sbjct 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARF-YAAEIASALGYLHS 215 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL----SREERVERIPWLAPEC 783 N+V+ ++ NILL G I L+D G+ + + +LAPE Sbjct 216 LNIVYRDLKPENILLDSQG-------HIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEV 268 Query 784 LPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE-HFYQRQHRLPEPSCPQLA 842 L +D W GA L E+ G P SR+ +E + + +L Sbjct 269 LH--KQPYDRTVDWWCLGAVLYEML-YGLPPFYSRNTAEMYDNILNKPLQLKPNITNSAR 325 Query 843 TLTSQCLTYEPTQR 856 L L + T+R Sbjct 326 HLLEGLLQKDRTKR 339 >sp|Q7Z8E9|STE20_PYRO7 Serine/threonine-protein kinase MST20 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507 GN=MST20 PE=3 SV=3 Length=914 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 55/274 (20%), Positives = 112/274 (41%), Gaps = 23/274 (8%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 + + +G+G G V G+ +VA+K + + P+ + EI +++ Sbjct 630 PREIYRSFTKIGQGASGGVYTGH----ERGSNRLVAIKQMNLEQQPK-KDLIINEILVMK 684 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMA 1012 H +I+ + GE L +VME++ GSL D + + + Q+ ++ G+ Sbjct 685 DSSHPNIVNFIDSYLCGGE--LWVVMEFMEGGSLTDVVTFNIMTEGQIASVCRETLLGLQ 742 Query 1013 YLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC 1072 +LH++ IHRD+ + N+LL + +K+ DFG + +E R +W APE Sbjct 743 HLHSKGVIHRDIKSDNILLSMEGNIKLTDFGFCATI---NEAQNKRTTMVGTPYWMAPEV 799 Query 1073 LKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGE 1132 + ++ D+WS G+ E++ + P E A + ++ + G Sbjct 800 VTRKEYGRKVDIWSLGIMAIEMI------EGEPPYLTESPLRALWLIATNGTPQIKDEG- 852 Query 1133 RLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + + + R + +L+ Sbjct 853 ------NMSPVFRDFLYFALKVDPDKRASAHDLL 880 Score = 181 bits (459), Expect = 3e-45, Method: Composition-based stats. Identities = 60/296 (20%), Positives = 96/296 (32%), Gaps = 45/296 (15%) Query 585 DQKEI-TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 D +EI + +GQG VY G +RG V +K Sbjct 629 DPREIYRSFTKIGQGASGGVYTGH------------------------ERGSNRLVAIKQ 664 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 ++ +M SH ++ + G E +V E++E G L + Sbjct 665 MNLEQQPKKDLIINEILVMKDSSHPNIVNFIDSYLCGGELWVVMEFMEGGSLTDVV--TF 722 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + V ++ L +L +K ++H ++ NILL+ G IKL+D G Sbjct 723 NIMTEGQIASVCRETLLGLQHLHSKGVIHRDIKSDNILLSMEG-------NIKLTDFGFC 775 Query 764 LGA----LSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 R V W+APE + +D W G +E+ +GE P + S Sbjct 776 ATINEAQNKRTTMVGTPYWMAPEVVT--RKEYGRKVDIWSLGIMAIEMI-EGEPPYLTES 832 Query 820 PSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P P L +P +R S +LR Sbjct 833 PLRALWLIATNGTPQIKDEGNMSPVFRDFLYFALKVDPDKRASAHDLLRHEFMNLC 888 >sp|Q9H4B4|PLK3_HUMAN Serine/threonine-protein kinase PLK3 OS=Homo sapiens OX=9606 GN=PLK3 PE=1 SV=2 Length=646 Score = 214 bits (544), Expect = 3e-57, Method: Composition-based stats. Identities = 67/267 (25%), Positives = 110/267 (41%), Gaps = 28/267 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHII 960 LG+G F + CY+ T+ TG AVK + P R EI++ R L H HI+ Sbjct 68 LGKGGFAR----CYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIV 123 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRD-YLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 ++ ED ++ + +E SL + RH++ ++ + +QI G+ YLH + Sbjct 124 RFSHHFEDAD--NIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGI 181 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDL N + + +K+GDFGLA + + + + APE L Sbjct 182 LHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKT---ICGTPNYVAPEVLLRQGHG 238 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 +DVWS G +Y LL SPP + +L R + + P Sbjct 239 PEADVWSLGCVMYTLLCG-----SPPFETADL-------KETYRCIKQV----HYTLPAS 282 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLI 1166 L+ RP+ + ++ Sbjct 283 LSLPARQLLAAILRASPRDRPSIDQIL 309 Score = 150 bits (379), Expect = 3e-36, Method: Composition-based stats. Identities = 52/342 (15%), Positives = 91/342 (27%), Gaps = 53/342 (15%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS--- 647 + LG+G YE D +KV+ S Sbjct 64 KGRLLGKGGFARCYEA------------------------TDTETGSAYAVKVIPQSRVA 99 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 L + H H+ + E L + + R + Sbjct 100 KPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLA-HIWKARHTLL 158 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 +Q+ S L YL + ++H ++ N + + +K+ D G+ Sbjct 159 EPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITE-------NMELKVGDFGLAARLE 211 Query 768 S----REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 ++ ++APE L D W G + + G P ++ E Sbjct 212 PPEQRKKTICGTPNYVAPEVLL--RQGHGPEADVWSLGCVMYTLLC-GSPPFETADLKET 268 Query 824 EH-FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNP 882 Q + LP L + L P RPS ILR + + + + Sbjct 269 YRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFFTKGYTPDRLPISSC 328 Query 883 DSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTG 924 + R L F KV+ + Sbjct 329 VTVPDLTPPNPARSL----------FAKVTKSLFGRKKKSKN 360 >sp|Q56UN5|M3K19_HUMAN Mitogen-activated protein kinase kinase kinase 19 OS=Homo sapiens OX=9606 GN=MAP3K19 PE=2 SV=1 Length=1328 Score = 221 bits (562), Expect = 3e-57, Method: Composition-based stats. Identities = 71/281 (25%), Positives = 121/281 (43%), Gaps = 31/281 (11%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCG-----PQHRSGWKQEIDIL 951 K LG+G +G V G+++AVK + D + ++E+D+L Sbjct 1061 WTKGEILGKGAYGTVYCG-----LTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLL 1115 Query 952 RTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQICEG 1010 + L H +I+ Y G C E ++ + ME+VP GS+ + R + + +QI +G Sbjct 1116 KALKHVNIVAYLGTCLQ--ENTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQG 1173 Query 1011 MAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVP----EGHEYYRVREDGDSPVF 1066 +AYLH +HRD+ NV+L ++K+ DFG A+ + G ++ +P + Sbjct 1174 VAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTP-Y 1232 Query 1067 WYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTE 1126 W APE + E + SD+WS G T++E+ T P + + Sbjct 1233 WMAPEVINESGYGRKSDIWSIGCTVFEMATGKP----PLASMDRMAAMFYIGAH------ 1282 Query 1127 LLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 RG P PD ++ C + RP+ L+ Sbjct 1283 ---RGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQLLK 1320 Score = 179 bits (454), Expect = 3e-44, Method: Composition-based stats. Identities = 62/293 (21%), Positives = 103/293 (35%), Gaps = 46/293 (16%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 T+ LG+G VY G ++ +D + L ++ Sbjct 1062 TKGEILGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEY---------------- 1105 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 E L+ + H ++ G C++ + E+V G + + G +P Sbjct 1106 ---RKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSII-NRFGPLPEM 1161 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL----- 764 +Q+ ++YL +VH ++ G N++L G+ IKL D G Sbjct 1162 VFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGI-------IKLIDFGCARRLAWA 1214 Query 765 ---GALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 G S + W+APE + + D W G T+ E+ G+ PL S Sbjct 1215 GLNGTHSDMLKSMHGTPYWMAPEVI--NESGYGRKSDIWSIGCTVFEMA-TGKPPLASMD 1271 Query 820 PSEKEHFYQRQHR-----LPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 FY HR LP+ A CLT + +RPS +L+ Sbjct 1272 -RMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQLLKHSF 1323 >sp|Q10407|MKH1_SCHPO MAP kinase kinase kinase mkh1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=mkh1 PE=3 SV=1 Length=1116 Score = 220 bits (560), Expect = 3e-57, Method: Composition-based stats. Identities = 77/312 (25%), Positives = 128/312 (41%), Gaps = 38/312 (12%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR--------- 941 K +G G +GKV L N TGE++AVK ++ R Sbjct 819 QNATFKWMKGELIGNGTYGKVFLAM----NINTGELIAVKQVEIPQTINGRHDQLRKDIV 874 Query 942 SGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLL 1001 EI ++ L H +I++Y G ++ E + + +EYV GS+ L + QL+ Sbjct 875 DSINAEISMIADLDHLNIVQYLGF--EKTETDISIFLEYVSGGSIGRCLRNYGPFEEQLV 932 Query 1002 LFA-QQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRED 1060 F +Q+ G++YLH++ IHRDL A N+L+D D + KI DFG++K + Sbjct 933 RFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDFDGVCKISDFGISKH-SDNVYDNDANLS 991 Query 1061 GDSPVFWYAPECL--KEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 +FW APE + + DVWS G + E+L + Sbjct 992 MQGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRRPWST--------------D 1037 Query 1119 MTVLRLTELLERGERLPRPDK----CPCEVYHLMKNCWETEASFRPTFENLIPI-LKTVH 1173 + + +L + P P + E + C+ A RPT E L+ Sbjct 1038 EAIQAMFKLGTEKKAPPIPSELVSQVSPEAIQFLNACFTVNADVRPTAEELLNHPFMKCD 1097 Query 1174 EKYQGQAPSVFS 1185 E++ + +++ Sbjct 1098 EEFNFKDTNLYD 1109 Score = 184 bits (466), Expect = 7e-46, Method: Composition-based stats. Identities = 83/557 (15%), Positives = 165/557 (30%), Gaps = 82/557 (15%) Query 338 GSSGSSGRNPQASLFGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKEHCVSIHR 397 S S+ + +D +P WA + K+ + + Sbjct 594 SSKSSNSLKESVEALSEIPFEDAPALDESDLSGDPFWA----------IQPKQSSSQVPK 643 Query 398 QDNKCLELSLPSRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHG---P 454 +++ ++ L A ++ +E++ P+ G Sbjct 644 ENHHNIQSKLSINTEA----------------ATDLKANELSSPKTPE----YCRGDDRS 683 Query 455 LLEPFVQAKLRPEDGLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAF 514 + + +LR I S + + + D + R FP D Sbjct 684 ISLSPLSYRLRKSKH---IRESPPSSKVINSGNWEVRPSADDLYEDVDRFFPRYDLDKVL 740 Query 515 VLEGWGRSFPSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARAS---- 570 V++ + + + R+ + ++R + Sbjct 741 VVDQSRMVSSPSKVSIRPKMKSVRLLAREASEARKEIRHNARRNKSGNLLRRSSTKLWGS 800 Query 571 ------PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 P T S + + + +G GT V+ +G+ K + Sbjct 801 RIVELKPDTTITSGSVVSQNATFKWMKGELIGNGTYGKVFLAM--NINTGELIAVKQVEI 858 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 + GR D DI + S+++ + H ++ G + Sbjct 859 PQTINGRH------------DQLRKDIVDSINAEISMIADLDHLNIVQYLGFEKTETDIS 906 Query 685 MVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLAR 744 + EYV G + LR G V++Q+ LSYL +K ++H ++ N+L+ Sbjct 907 IFLEYVSGGSIGRCLR-NYGPFEEQLVRFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDF 965 Query 745 LGLAEGTSPFIKLSDPGVGL------GALSREERVERIPWLAPECLPGGANSLSTAMDKW 798 G+ K+SD G+ + I W+APE + S +D W Sbjct 966 DGV-------CKISDFGISKHSDNVYDNDANLSMQGSIFWMAPEVIHNDHQGYSAKVDVW 1018 Query 799 GFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------CPQLATLTSQCLTY 851 G +LE+ G P + + + + P P+ + C T Sbjct 1019 SLGCVVLEMLA-GRRPWSTDEAIQAMFKLGTEKKAPPIPSELVSQVSPEAIQFLNACFTV 1077 Query 852 EPTQRPSFRTILRDLTR 868 RP+ +L Sbjct 1078 NADVRPTAEELLNHPFM 1094 >sp|Q08942|NRKA_TRYBB Putative serine/threonine-protein kinase A OS=Trypanosoma brucei brucei OX=5702 GN=NRKA PE=2 SV=1 Length=431 Score = 208 bits (529), Expect = 3e-57, Method: Composition-based stats. Identities = 63/273 (23%), Positives = 109/273 (40%), Gaps = 29/273 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G +G+ Y + G + K + + + + + EI L H +II+ Sbjct 26 VGLGSYGE----AYVAESVEDGSLCVAKVMDLSKMSQRDKRYAQSEIKCLANCNHPNIIR 81 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQICEGMAYLH 1015 Y + + L +VME+ G+L + + + L Q+C + Y+H Sbjct 82 YIE--DHEENDRLLIVMEFADSGNLDEQIKLRGSGDARYFQEHEALFLFLQLCLALDYIH 139 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + +HRD+ + NVLL + LVK+GDFG + + +P ++ APE Sbjct 140 SHKMLHRDIKSANVLLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTP-YYLAPELWNN 198 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 ++ +DVWS GV LYE++ P L G L + G P Sbjct 199 KRYNKKADVWSLGVLLYEIM-----GMKKPFSASNLKG----------LMSKVLAGTYAP 243 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIPI 1168 PD E ++ + + RP+ + I Sbjct 244 LPDSFSSEFKRVVDGILVADPNDRPSVREIFQI 276 Score = 150 bits (380), Expect = 9e-38, Method: Composition-based stats. Identities = 54/290 (19%), Positives = 91/290 (31%), Gaps = 29/290 (10%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + LG GR + G G + D L V KV+D S Sbjct 5 FSTILGTDGSG----GRCKYLNKGIVGLGSYGEAYVAESVEDGS--LCVA-KVMDLSKMS 57 Query 651 IALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR----RERG 704 Y ++ +H ++ ++V E+ + G LD ++ + Sbjct 58 QRDKRYAQSEIKCLANCNHPNIIRYIEDHEENDRLLIVMEFADSGNLDEQIKLRGSGDAR 117 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + + QL AL Y+ + ++H ++ N+LL GL +KL D G Sbjct 118 YFQEHEALFLFLQLCLALDYIHSHKMLHRDIKSANVLLTSTGL-------VKLGDFGFSH 170 Query 765 GALSR------EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL-QS 817 +LAPE + D W G L EI + + Sbjct 171 QYEDTVSGVVASTFCGTPYYLAPEL--WNNKRYNKKADVWSLGVLLYEIMGMKKPFSASN 228 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + LP+ + + L +P RPS R I + Sbjct 229 LKGLMSKVLAGTYAPLPDSFSSEFKRVVDGILVADPNDRPSVREIFQIPY 278 >sp|P28582|CDPK_DAUCA Calcium-dependent protein kinase OS=Daucus carota OX=4039 PE=2 SV=2 Length=532 Score = 211 bits (536), Expect = 3e-57, Method: Composition-based stats. Identities = 72/301 (24%), Positives = 118/301 (39%), Gaps = 30/301 (10%) Query 874 LADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL- 932 V ++ P + ++LG G FG V Y T + +G++ A K++ Sbjct 58 PRQVHRPESNTILGKPFEDIRGKYTLGKELGRGQFGCV----YQCTENSSGQLYACKSIL 113 Query 933 -KADCGPQHRSGWKQEIDILRTLYH-EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD-Y 989 + + K+EI IL+ L +I+++KG ED+ +S+ LVME G L D Sbjct 114 KRKLVSKNDKEDIKREIQILQHLSGQPNIVEFKGVFEDR--QSVHLVMELCAGGELFDRI 171 Query 990 LPRHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL---DNDRLVKIGDFGLAK 1046 + + +QI + H +HRDL N LL D D ++K DFGL+ Sbjct 172 IAQGHYSERAAATICRQIVNVVHVCHFMGVMHRDLKPENFLLSSKDKDAMLKATDFGLSV 231 Query 1047 AVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPT 1106 + EG Y + ++ APE L+ + D+WS GV LY LL+ Sbjct 232 FIEEGKVY----RNIVGSAYYVAPEVLRRS-YGKEIDIWSAGVILYILLSGVPPF----- 281 Query 1107 KFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + + E + E P P L++ + R T ++ Sbjct 282 ------WAENEKGIFDAILEGVIDFESEPWP-SVSNSAKDLVRKMLTQDPRRRITSAQVL 334 Query 1167 P 1167 Sbjct 335 D 335 Score = 141 bits (355), Expect = 8e-34, Method: Composition-based stats. Identities = 51/307 (17%), Positives = 94/307 (31%), Gaps = 40/307 (13%) Query 571 PRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPG 630 P + + F + + + T LG+G VY + SG K + LV Sbjct 64 PESNTILGKPFEDI-RGKYTLGKELGRGQFGCVY--QCTENSSGQLYACKSILKRKLVSK 120 Query 631 RDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS-HTHLAFVHGVCVRGPENIMVTEY 689 D+ ++ +S ++ GV +V E Sbjct 121 NDK-------------------EDIKREIQILQHLSGQPNIVEFKGVFEDRQSVHLVMEL 161 Query 690 VEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAE 749 G L + + GH + +Q+ + + ++H ++ N LL+ + Sbjct 162 CAGGELFDRIIAQ-GHYSERAAATICRQIVNVVHVCHFMGVMHRDLKPENFLLSS----K 216 Query 750 GTSPFIKLSDPGVGLGALSREER---VERIPWLAPECLPGGANSLSTAMDKWGFGATLLE 806 +K +D G+ + + V ++APE L S +D W G L Sbjct 217 DKDAMLKATDFGLSVFIEEGKVYRNIVGSAYYVAPEVLR---RSYGKEIDIWSAGVILY- 272 Query 807 ICFDGEAPLQ-----SRSPSEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRT 861 I G P + E + L + LT +P +R + Sbjct 273 ILLSGVPPFWAENEKGIFDAILEGVIDFESEPWPSVSNSAKDLVRKMLTQDPRRRITSAQ 332 Query 862 ILRDLTR 868 +L Sbjct 333 VLDHPWM 339 >sp|P59241|AURKA_RAT Aurora kinase A OS=Rattus norvegicus OX=10116 GN=Aurka PE=1 SV=1 Length=397 Score = 207 bits (526), Expect = 3e-57, Method: Composition-based stats. Identities = 64/296 (22%), Positives = 109/296 (37%), Gaps = 33/296 (11%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRS-GWKQEI 948 + R LG+G FG V L + ++A+K L K ++E+ Sbjct 120 QWTLEDFDIGRPLGKGKFGNVYL----AREKQSKFILALKVLFKVQLEKAGVEHQLRREV 175 Query 949 DILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR-HSIGLAQLLLFAQQI 1007 +I L H +I++ G D + L++EY PLG++ L + + + ++ Sbjct 176 EIQSHLRHPNILRLYGYFHDAT--RVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 233 Query 1008 CEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFW 1067 ++Y H++ IHRD+ N+LL ++ +KI DFG + P R + + Sbjct 234 ANALSYCHSKRVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSR-----RTTLCGTLDY 288 Query 1068 YAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 PE ++ D+WS GV YE L + A R Sbjct 289 QPPEMIEGRMHDEKVDLWSLGVLCYEFLVGMPPFE------------AHTYQETYRRISR 336 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSV 1183 +E PD L+ + +S R T + L+ K P Sbjct 337 VE----FTFPDFVTEGARDLISRLLKHNSSQRLTLAEV---LEHPWIKANSSKPPT 385 Score = 178 bits (452), Expect = 2e-47, Method: Composition-based stats. Identities = 62/350 (18%), Positives = 121/350 (35%), Gaps = 48/350 (14%) Query 524 PSVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHR 583 P +++L AA R + ++ PQP + N + + Sbjct 68 PVLKQLPAA---SGPRPASRLSNPQKSEQPQPAASGN----NSEKEQTSIQKTEDSKKRQ 120 Query 584 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV 643 ++ LG+G NVY R++ + + LKV Sbjct 121 WTLEDFDIGRPLGKGKFGNVYLA------------------------REKQSKFILALKV 156 Query 644 LDPSHHD---IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 L + + + S + H ++ ++G ++ EY G + L+ Sbjct 157 LFKVQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQ 216 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + +LA+ALSY +K ++H ++ N+LL G++ +K++D Sbjct 217 KL-SKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLL-------GSNGELKIADF 268 Query 761 GVGLGALS--REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 G + A S R + + PE + G + +D W G E G P ++ Sbjct 269 GWSVHAPSSRRTTLCGTLDYQPPEMIEGRMH--DEKVDLWSLGVLCYEFLV-GMPPFEAH 325 Query 819 SPSEK-EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 + E + + P+ L S+ L + +QR + +L Sbjct 326 TYQETYRRISRVEFTFPDFVTEGARDLISRLLKHNSSQRLTLAEVLEHPW 375 >sp|P26696|MK01_XENLA Mitogen-activated protein kinase 1 OS=Xenopus laevis OX=8355 GN=mapk1 PE=1 SV=3 Length=361 Score = 205 bits (522), Expect = 3e-57, Method: Composition-based stats. Identities = 61/276 (22%), Positives = 106/276 (38%), Gaps = 24/276 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKY 962 +GEG +G V ++ VA+K + + +EI IL HE+II Sbjct 34 IGEGAYGMVCSAH----DNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFKHENIIGI 89 Query 963 KGCCEDQG---EKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 K + +V + + L L + + F QI G+ Y+H+ + Sbjct 90 NDIIRAPTIEQMKDVYIVQDLME-TDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANV 148 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC-LKEYKF 1078 +HRDL N+LL+ +KI DFGLA+ H++ + + ++ APE L + Sbjct 149 LHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGY 208 Query 1079 YYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGI--AQGQMTVLRLTELLERGERL 1134 + D+WS G L E+L++ + + ++GI + Q + + L R L Sbjct 209 TKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLL 268 Query 1135 PRP-----------DKCPCEVYHLMKNCWETEASFR 1159 P + L+ R Sbjct 269 SLPHKNKVPWNRLFPNADPKALDLLDKMLTFNPHKR 304 Score = 132 bits (332), Expect = 5e-32, Method: Composition-based stats. Identities = 37/245 (15%), Positives = 80/245 (33%), Gaps = 48/245 (20%) Query 595 LGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA-L 653 +G+G V D ++RV +K + P H Sbjct 34 IGEGAYGMVCSAH------------------------DNVNKVRVAIKKISPFEHQTYCQ 69 Query 654 AFYETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDVWLRRERGHVPM 708 ++ + H ++ ++ + + +V + +E L L+ + H+ Sbjct 70 RTLREIKILLRFKHENIIGINDIIRAPTIEQMKDVYIVQDLME-TDLYKLLKTQ--HLSN 126 Query 709 AWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS 768 Q+ L Y+ + N++H ++ N+LL T+ +K+ D G+ A Sbjct 127 DHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLN-------TTCDLKICDFGLARVADP 179 Query 769 REERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPS 821 + + APE + + + ++D W G L E+ + Sbjct 180 DHDHTGFLTEYVATRWYRAPE-IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLD 238 Query 822 EKEHF 826 + H Sbjct 239 QLNHI 243 >sp|Q9NRH2|SNRK_HUMAN SNF-related serine/threonine-protein kinase OS=Homo sapiens OX=9606 GN=SNRK PE=1 SV=2 Length=765 Score = 216 bits (550), Expect = 3e-57, Method: Composition-based stats. Identities = 65/269 (24%), Positives = 106/269 (39%), Gaps = 31/269 (12%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHII 960 LG GHF V L + TGE VAVK + K QE+ ++ + H +I+ Sbjct 21 TLGRGHFAVVKL----ARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHPNIV 76 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQH 1018 + + Q + L L++E G + DY+ +H + + QI ++Y H H Sbjct 77 RLYEVIDTQTK--LYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134 Query 1019 YIHRDLAARN-VLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL N V + LVK+ DFG + G + + + APE L + Sbjct 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKL----TTSCGSLAYSAPEILLGDE 190 Query 1078 FY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 + A D+WS GV L+ L+ Q A T+ + + + Sbjct 191 YDAPAVDIWSLGVILFMLVCGQPPFQE-----------ANDSETLTMIMDC-----KYTV 234 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENL 1165 P E L+ + + R + E + Sbjct 235 PSHVSKECKDLITRMLQRDPKRRASLEEI 263 Score = 172 bits (437), Expect = 5e-43, Method: Composition-based stats. Identities = 50/281 (18%), Positives = 95/281 (34%), Gaps = 38/281 (14%) Query 593 SHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIA 652 LG+G V R G +V +KV+D + D Sbjct 20 KTLGRGHFAVVKLARHVFTGE------------------------KVAVKVIDKTKLDTL 55 Query 653 LA--FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 ++ M V H ++ ++ V + ++ E + G + ++ + + Sbjct 56 ATGHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDL 115 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG---LGAL 767 Q+ A+SY ++VH ++ N+ + +KL+D G Sbjct 116 AKKYFAQIVHAISYCHKLHVVHRDLKPENV------VFFEKQGLVKLTDFGFSNKFQPGK 169 Query 768 SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 + + APE L G + A+D W G L + G+ P Q + SE Sbjct 170 KLTTSCGSLAYSAPEILLGDEYD-APAVDIWSLGVIL-FMLVCGQPPFQEANDSETLTMI 227 Query 828 QR-QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 ++ +P + L ++ L +P +R S I Sbjct 228 MDCKYTVPSHVSKECKDLITRMLQRDPKRRASLEEIENHPW 268 >sp|Q55GV3|PAKC_DICDI Serine/threonine-protein kinase pakC OS=Dictyostelium discoideum OX=44689 GN=pakC PE=1 SV=2 Length=477 Score = 209 bits (532), Expect = 3e-57, Method: Composition-based stats. Identities = 60/278 (22%), Positives = 114/278 (41%), Gaps = 26/278 (9%) Query 893 HKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILR 952 + K + +GEG G+V + T+ + VA+K + + + EI I++ Sbjct 200 PTKIYKNMTKIGEGAAGEV----FVATSSKNNKRVAIKKI--EINNDNAKLLVTEIAIMK 253 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP---RHSIGLAQLLLFAQQICE 1009 T +H++I+ Y ++ L + ME++ G L D L + Q+ ++ + Sbjct 254 TSHHDNIVNYIDSYIV-NDRELWVAMEFMGGGCLTDILEAFDNIKMSEIQIAYVVKETLK 312 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYA 1069 + Y+H+ H IHRD+ + N+LL ++ VKI DFG A + + + R +W A Sbjct 313 ALQYIHSLHRIHRDIKSDNILLGSEGSVKIADFGYAAQLTQ---KQQKRNTVVGTPYWMA 369 Query 1070 PECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLE 1129 PE ++ + + D+WS G+ + E+ P + +G + T Sbjct 370 PELIRGHDYGVKVDIWSLGIMMMEMAEGEPPYMDFPPLRALFLITTKGIPPLKETT---- 425 Query 1130 RGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 K C + + RP +L+ Sbjct 426 ---------KWSKTFQDFFSKCLDINVANRPDATDLLK 454 Score = 177 bits (449), Expect = 3e-46, Method: Composition-based stats. Identities = 68/409 (17%), Positives = 129/409 (32%), Gaps = 46/409 (11%) Query 470 LYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFPSVREL 529 ++ + + V + S+ Q L+ + A G + + + + Sbjct 86 FFIQANTPDEMASWMKAVEKGSEYSTVSQPFNLKHEVHVDFNSATGFSGLPKEWEVILKS 145 Query 530 GAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEI 589 + +L + S+ + E SN + A L LS L K Sbjct 146 SNVSKQEVLDKPSEWLSVLEFQAGRTMEKSNSQNL-SALPDESNLTLSDLVTKEDPTKIY 204 Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 ++ +G+G V+ RV +K ++ ++ Sbjct 205 KNMTKIGEGAAGEVF------------------------VATSSKNNKRVAIKKIEINN- 239 Query 650 DIALAFYETASLMSQVSHTHLAFVHG-VCVRGPENIMVTEYVEHGPLDVWLRR-ERGHVP 707 D A ++M H ++ V E + E++ G L L + + Sbjct 240 DNAKLLVTEIAIMKTSHHDNIVNYIDSYIVNDRELWVAMEFMGGGCLTDILEAFDNIKMS 299 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 V ++ AL Y+ + + +H ++ NILL G+ +K++D G Sbjct 300 EIQIAYVVKETLKALQYIHSLHRIHRDIKSDNILL-------GSEGSVKIADFGYAAQLT 352 Query 768 ----SREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK 823 R V W+APE + G + +D W G ++E+ +GE P P Sbjct 353 QKQQKRNTVVGTPYWMAPELIRG--HDYGVKVDIWSLGIMMMEMA-EGEPPYMDFPPLRA 409 Query 824 EHFYQRQHRLP----EPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTR 868 + P S+CL RP +L+ Sbjct 410 LFLITTKGIPPLKETTKWSKTFQDFFSKCLDINVANRPDATDLLKHPFM 458 >sp|Q54XZ5|Y0138_DICDI Probable serine/threonine-protein kinase DDB_G0278509 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0278509 PE=3 SV=1 Length=1248 Score = 220 bits (561), Expect = 3e-57, Method: Composition-based stats. Identities = 79/356 (22%), Positives = 136/356 (38%), Gaps = 65/356 (18%) Query 860 RTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPT 919 R Q + + ++ +G+G F KV + Sbjct 909 RQSSFQQIPQQFNLSTSTTNITKLPRIKYTWEIDFDEIQFFNLIGQGGFSKVYHGVWRSK 968 Query 920 NDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY-HEHIIKYKGCCEDQGEKSLQLVM 978 + VA+K ++ + +++E+ IL L HE+++ Y G C + ++ Sbjct 969 D------VAIKQIELQNN-KSLDDFRREVGILSKLKPHENLLAYYGAC--KHANYCYIIT 1019 Query 979 EYVPLGSLRDYLPRH---SIGLAQLLLFAQQICEGMAYLH--AQHYIHRDLAARNVLLDN 1033 EY+P GSL D L R + Q + FA + G +L H DL +N+L+ N Sbjct 1020 EYLPRGSLHDLLHREQLMKLDFKQKVSFAICVALGCYHLSTYEPPIYHTDLKTKNLLVTN 1079 Query 1034 DRLVKIGDFGLAKAVPEG-----------------------------------HEYYRVR 1058 +KI DFGLA + + V Sbjct 1080 ALKIKIADFGLASFAKKSLTTIINNNNNTNNTATSSTTTSSANGANSISNNNNNGTTSVD 1139 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 + + F+ APE L F SDV+SFG L+EL+T+ Sbjct 1140 QSRLAYAFYAAPEILNSKHFSEKSDVFSFGTILWELVTNKIPFD---------------G 1184 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHE 1174 M + ELL+ G+RL P+ C + +++++CW ++ RPTF ++ L+ + + Sbjct 1185 MDPYEVKELLKSGKRLEIPENCNEVLKNIIQDCWNQQSEDRPTFLSIYHRLENLMK 1240 Score = 185 bits (469), Expect = 4e-46, Method: Composition-based stats. Identities = 70/367 (19%), Positives = 124/367 (34%), Gaps = 88/367 (24%) Query 556 GETSNLIIMRGARASPRTLNLSQLS----FHRVDQKEITQLSHLGQGTRTNVYEGRLRVE 611 ++S I + S T N+++L +D EI + +GQG + VY G R + Sbjct 909 RQSSFQQIPQQFNLSTSTTNITKLPRIKYTWEIDFDEIQFFNLIGQGGFSKVYHGVWRSK 968 Query 612 GSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVS-HTHL 670 V +K ++ ++ F ++S++ H +L Sbjct 969 D--------------------------VAIKQIELQNNKSLDDFRREVGILSKLKPHENL 1002 Query 671 AFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER-GHVPMAWKMVVAQQLASALSYLE--N 727 +G C ++TEY+ G L L RE+ + K+ A +A +L Sbjct 1003 LAYYGACKHANYCYIITEYLPRGSLHDLLHREQLMKLDFKQKVSFAICVALGCYHLSTYE 1062 Query 728 KNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS------------------- 768 + H ++ +N+L+ + IK++D G+ A Sbjct 1063 PPIYHTDLKTKNLLVTN-------ALKIKIADFGLASFAKKSLTTIINNNNNTNNTATSS 1115 Query 769 -----------------------REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLL 805 + R+ + APE L + S D + FG L Sbjct 1116 TTTSSANGANSISNNNNNGTTSVDQSRLAYAFYAAPEIL--NSKHFSEKSDVFSFGTILW 1173 Query 806 EICFDGEAPLQSRSPSEKEHFYQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 E+ + + P P E + + RL PE L + C + RP+F +I Sbjct 1174 ELVTN-KIPFDGMDPYEVKELLKSGKRLEIPENCNEVLKNIIQDCWNQQSEDRPTFLSIY 1232 Query 864 RDLTRLQ 870 L L Sbjct 1233 HRLENLM 1239 >sp|O14427|CLA4_CANAX Serine/threonine-protein kinase CLA4 OS=Candida albicans OX=5476 GN=CLA4 PE=3 SV=1 Length=971 Score = 219 bits (557), Expect = 3e-57, Method: Composition-based stats. Identities = 62/268 (23%), Positives = 112/268 (42%), Gaps = 23/268 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 G+G G V L +A+K + D P+ + EI +++ H++I+ Sbjct 685 KAGQGASGNVYLAE---MIKDNNRKIAIKQMDLDAQPR-KELIINEILVMKDSQHKNIVN 740 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G+ L ++MEY+ GSL + + + + Q+ + +G+ +LH +H Sbjct 741 FLDSYLI-GDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIATICFETLKGLQHLHKKHI 799 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ + NVLLD VKI DFG + + R +W APE +K+ ++ Sbjct 800 IHRDIKSDNVLLDAYGNVKITDFGFCAKLTDQRN---KRATMVGTPYWMAPEVVKQKEYD 856 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 DVWS G+ E++ PP E + T +L +P+ Sbjct 857 EKVDVWSLGIMTIEMI-----EGEPPYLNEEPLKALYLIATNGT--------PKLKKPEL 903 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + C + +R + + L+ Sbjct 904 LSNSIKKFLSICLCVDVRYRASTDELLE 931 Score = 189 bits (481), Expect = 6e-48, Method: Composition-based stats. Identities = 57/346 (16%), Positives = 104/346 (30%), Gaps = 62/346 (18%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHL----------------- 595 P P + SN + + T QL R ++ ++ L Sbjct 626 PSPTDKSNKPTAPASGPA-VTKTAKQLKKERERLNDLQIIAKLKTVVNNQDPKPLFRIVE 684 Query 596 --GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 GQG NVY + + ++ +K +D Sbjct 685 KAGQGASGNVY-----------------------LAEMIKDNNRKIAIKQMDLDAQPRKE 721 Query 654 AFYETASLMSQVSHTHLAFVHG-VCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 +M H ++ + E ++ EY++ G L + + Sbjct 722 LIINEILVMKDSQHKNIVNFLDSYLIGDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIA 781 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS---- 768 + + L +L K+++H ++ N+LL G +K++D G Sbjct 782 TICFETLKGLQHLHKKHIIHRDIKSDNVLLDAYG-------NVKITDFGFCAKLTDQRNK 834 Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 R V W+APE + +D W G +E+ +GE P + P + + Sbjct 835 RATMVGTPYWMAPEVVKQ--KEYDEKVDVWSLGIMTIEMI-EGEPPYLNEEPLKALYLIA 891 Query 829 RQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 PE + S CL + R S +L Sbjct 892 TNGTPKLKKPELLSNSIKKFLSICLCVDVRYRASTDELLEHSFIQH 937 >sp|Q39026|MPK6_ARATH Mitogen-activated protein kinase 6 OS=Arabidopsis thaliana OX=3702 GN=MPK6 PE=1 SV=1 Length=395 Score = 206 bits (525), Expect = 3e-57, Method: Composition-based stats. Identities = 71/318 (22%), Positives = 115/318 (36%), Gaps = 31/318 (10%) Query 879 TVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCG 937 + + +Y I +G+G +G V N T E VA+K + A Sbjct 45 RFIQYNIFGNIFEVTAKYKPPIMPIGKGAYGIVC----SAMNSETNESVAIKKIANAFDN 100 Query 938 PQHRSGWKQEIDILRTLYHEHIIKYKGCC---EDQGEKSLQLVMEYVPLGSLRDYLP-RH 993 +EI +LR + HE+I+ + + + E + L + Sbjct 101 KIDAKRTLREIKLLRHMDHENIVAIRDIIPPPLRNAFNDVYIAYELMD-TDLHQIIRSNQ 159 Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 ++ F QI G+ Y+H+ + +HRDL N+LL+ + +KI DFGLA+ E Sbjct 160 ALSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTSESD- 218 Query 1054 YYRVREDGDSPVFWYAPE-CLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTK 1107 + ++ APE L + A DVWS G EL+ Sbjct 219 ---FMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRL 275 Query 1108 FLELIGIA------QGQMTVLRLTELLERGERLPRPDKCP---CEVYHLMKNCWETEASF 1158 +ELIG R L R DK P L++ + Sbjct 276 LMELIGTPSEEELEFLNENAKRYIRQLPPYPRQSITDKFPTVHPLAIDLIEKMLTFDPRR 335 Query 1159 RPTFENLI--PILKTVHE 1174 R T + + P L ++H+ Sbjct 336 RITVLDALAHPYLNSLHD 353 Score = 127 bits (319), Expect = 5e-30, Method: Composition-based stats. Identities = 33/221 (15%), Positives = 75/221 (34%), Gaps = 26/221 (12%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAF--YE 657 N++E + + + + V +K + + + A Sbjct 52 FGNIFE--VTAKYKPPIMPIGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAKRTLR 109 Query 658 TASLMSQVSHTHLAFVHGVCVRGPEN-------IMVTEYVEHGPLDVWLRRERGHVPMAW 710 L+ + H ++ + + P + E ++ L +R + + Sbjct 110 EIKLLRHMDHENIVAIRDII--PPPLRNAFNDVYIAYELMD-TDLHQIIRSNQA-LSEEH 165 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 Q+ L Y+ + N++H ++ N+LL + +K+ D G+ + Sbjct 166 CQYFLYQILRGLKYIHSANVLHRDLKPSNLLLN-------ANCDLKICDFGLARVTSESD 218 Query 771 ---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 E V + APE L ++ + A+D W G +E+ Sbjct 219 FMTEYVVTRWYRAPELLLN-SSDYTAAIDVWSVGCIFMELM 258 >sp|Q5APR8|CLA4_CANAL Serine/threonine-protein kinase CLA4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=CLA4 PE=1 SV=1 Length=976 Score = 219 bits (557), Expect = 3e-57, Method: Composition-based stats. Identities = 62/268 (23%), Positives = 112/268 (42%), Gaps = 23/268 (9%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIK 961 G+G G V L +A+K + D P+ + EI +++ H++I+ Sbjct 690 KAGQGASGNVYLAE---MIKDNNRKIAIKQMDLDAQPR-KELIINEILVMKDSQHKNIVN 745 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH--SIGLAQLLLFAQQICEGMAYLHAQHY 1019 + G+ L ++MEY+ GSL + + + + Q+ + +G+ +LH +H Sbjct 746 FLDSYLI-GDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIATICFETLKGLQHLHKKHI 804 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 IHRD+ + NVLLD VKI DFG + + R +W APE +K+ ++ Sbjct 805 IHRDIKSDNVLLDAYGNVKITDFGFCAKLTDQRN---KRATMVGTPYWMAPEVVKQKEYD 861 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 DVWS G+ E++ PP E + T +L +P+ Sbjct 862 EKVDVWSLGIMTIEMI-----EGEPPYLNEEPLKALYLIATNGT--------PKLKKPEL 908 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + C + +R + + L+ Sbjct 909 LSNSIKKFLSICLCVDVRYRASTDELLE 936 Score = 189 bits (481), Expect = 7e-48, Method: Composition-based stats. Identities = 57/346 (16%), Positives = 104/346 (30%), Gaps = 62/346 (18%) Query 553 PQPGETSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHL----------------- 595 P P + SN + + T QL R ++ ++ L Sbjct 631 PSPTDKSNKPTAPASGPA-VTKTAKQLKKERERLNDLQIIAKLKTVVNNQDPKPLFRIVE 689 Query 596 --GQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 GQG NVY + + ++ +K +D Sbjct 690 KAGQGASGNVY-----------------------LAEMIKDNNRKIAIKQMDLDAQPRKE 726 Query 654 AFYETASLMSQVSHTHLAFVHG-VCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKM 712 +M H ++ + E ++ EY++ G L + + Sbjct 727 LIINEILVMKDSQHKNIVNFLDSYLIGDNELWVIMEYMQGGSLTEIIENNDFKLNEKQIA 786 Query 713 VVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS---- 768 + + L +L K+++H ++ N+LL G +K++D G Sbjct 787 TICFETLKGLQHLHKKHIIHRDIKSDNVLLDAYG-------NVKITDFGFCAKLTDQRNK 839 Query 769 REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQ 828 R V W+APE + +D W G +E+ +GE P + P + + Sbjct 840 RATMVGTPYWMAPEVVKQ--KEYDEKVDVWSLGIMTIEMI-EGEPPYLNEEPLKALYLIA 896 Query 829 RQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQ 870 PE + S CL + R S +L Sbjct 897 TNGTPKLKKPELLSNSIKKFLSICLCVDVRYRASTDELLEHSFIQH 942 >sp|Q9CAU7|NEK2_ARATH Serine/threonine-protein kinase Nek2 OS=Arabidopsis thaliana OX=3702 GN=NEK2 PE=2 SV=1 Length=606 Score = 213 bits (541), Expect = 3e-57, Method: Composition-based stats. Identities = 63/293 (22%), Positives = 124/293 (42%), Gaps = 34/293 (12%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHIIK 961 +G+G FG L + ++ +K ++ A + R QE++++ +++ I++ Sbjct 10 IGKGSFGSALLV----RHKHEKKLYVLKKIRLARQTGRTRRSAHQEMELISKIHNPFIVE 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018 YK ++G + +++ Y G + + + + + +L + QI + YLHA H Sbjct 66 YKDSWVEKG-CYVCIIIGYCKGGDMAEAIKKTNGVHFTEEKLCKWLVQILLALEYLHANH 124 Query 1019 YIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKF 1078 +HRD+ N+ L D+ +++GDFGLAK + + + PE L + + Sbjct 125 ILHRDVKCSNIFLTKDQDIRLGDFGLAKVLTSDD----LASSVVGTPSYMCPELLADIPY 180 Query 1079 YYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPD 1138 SD+WS G +YE+ ++ P K ++ G L + R P P Sbjct 181 GSKSDIWSLGCCMYEM-----TAMKPAFKAFDMQG----------LINRINRSIVPPLPA 225 Query 1139 KCPCEVYHLMKNCWETEASFRPTFENLI------PILKTVHEKYQGQAPSVFS 1185 + L+K+ RP+ L+ P ++ +H K +V Sbjct 226 QYSAAFRGLVKSMLRKNPELRPSAAELLRQPLLQPYIQKIHLKVNDPGSNVLP 278 Score = 139 bits (351), Expect = 7e-33, Method: Composition-based stats. Identities = 50/290 (17%), Positives = 91/290 (31%), Gaps = 43/290 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VL 644 + L +G+G+ + R + E ++L V+ K L Sbjct 1 MENYEVLEQIGKGSFGSALLVRHKHE-----------------------KKLYVLKKIRL 37 Query 645 DPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGP-ENIMVTEYVEHGPLDVWLRRER 703 + ++ L+S++ + + V ++ Y + G + +++ Sbjct 38 ARQTGRTRRSAHQEMELISKIHNPFIVEYKDSWVEKGCYVCIIIGYCKGGDMAEAIKKTN 97 Query 704 G-HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 G H Q+ AL YL +++H +V NI L + I+L D G+ Sbjct 98 GVHFTEEKLCKWLVQILLALEYLHANHILHRDVKCSNIFLTK-------DQDIRLGDFGL 150 Query 763 GLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 S + V ++ PE L + D W G + E+ P Sbjct 151 AKVLTSDDLASSVVGTPSYMCPELLAD--IPYGSKSDIWSLGCCMYEM--TAMKPAFKAF 206 Query 820 PSEKEHFYQRQ---HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDL 866 + + LP L L P RPS +LR Sbjct 207 DMQGLINRINRSIVPPLPAQYSAAFRGLVKSMLRKNPELRPSAAELLRQP 256 >sp|Q9QYZ3|SMK2B_MOUSE Sperm motility kinase 2B OS=Mus musculus OX=10090 GN=Smok2b PE=1 SV=1 Length=484 Score = 209 bits (532), Expect = 3e-57, Method: Composition-based stats. Identities = 63/279 (23%), Positives = 104/279 (37%), Gaps = 30/279 (11%) Query 890 TVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEID 949 + +G G KV L + TG VAVK ++ + E++ Sbjct 1 MENFHAQYVMLETIGHGGCSKVML----ARHRLTGSHVAVKMIRK--SECWCNPVMSEVE 54 Query 950 ILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQIC 1008 +L H +II E + K + L+ME SL ++ + + +Q+ Sbjct 55 LLMMADHPNIISLLQVIETK--KKVYLIMELCEGKSLYQHIRNAGYLQEDEARALFKQLL 112 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 M Y H Q +HRDL N++++ D VKI DFGL V G + + Sbjct 113 SAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLGTQVKPGQKL----NLFCGTYPFS 168 Query 1069 APECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 APE L + DVW+ GV LY ++T + ++ +L Sbjct 169 APEVLLSRPYDGPKIDVWTLGVVLYFMVTGKVPFDAA---------------SIQKLVRQ 213 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLI 1166 + G+ P + E+ L+ RPT ++ Sbjct 214 ILAGKYF-VPSRLSVELRDLISLLMTANPKLRPTVAEVM 251 Score = 167 bits (423), Expect = 7e-43, Method: Composition-based stats. Identities = 55/306 (18%), Positives = 105/306 (34%), Gaps = 39/306 (13%) Query 588 EITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS 647 + L +G G + V R R+ GS V +K++ S Sbjct 7 QYVMLETIGHGGCSKVMLARHRLTGS------------------------HVAVKMIRKS 42 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 L+ H ++ + V + ++ E E L +R G++ Sbjct 43 EC-WCNPVMSEVELLMMADHPNIISLLQVIETKKKVYLIMELCEGKSLYQHIRNA-GYLQ 100 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 + +QL SA++Y N+ +VH ++ NI++ + G +K+ D G+G Sbjct 101 EDEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDG-------KVKIIDFGLGTQVK 153 Query 768 SREE---RVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE-K 823 ++ P+ APE L +D W G L + G+ P + S + Sbjct 154 PGQKLNLFCGTYPFSAPEVLLSRPYD-GPKIDVWTLGVVLYFMV-TGKVPFDAASIQKLV 211 Query 824 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 ++ +P +L L S +T P RP+ ++ + + Sbjct 212 RQILAGKYFVPSRLSVELRDLISLLMTANPKLRPTVAEVMVHPWVTEGSGVFPDPCEEQM 271 Query 884 SPASDP 889 +P Sbjct 272 PLKPNP 277 >sp|P67998|KS6B1_RABIT Ribosomal protein S6 kinase beta-1 OS=Oryctolagus cuniculus OX=9986 GN=RPS6KB1 PE=2 SV=1 Length=525 Score = 210 bits (535), Expect = 3e-57, Method: Composition-based stats. Identities = 70/292 (24%), Positives = 115/292 (39%), Gaps = 26/292 (9%) Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931 + ++ S P + +R LG+G +GKV T TG++ A+K Sbjct 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKV 124 Query 932 LKADC---GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 LK + + K E +IL + H I+ + G+ L L++EY+ G L Sbjct 125 LKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGK--LYLILEYLSGGELFM 182 Query 989 YLPRHSIG-LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 L R I + +I + +LH + I+RDL N++L++ VK+ DFGL K Sbjct 183 QLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK- 241 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 E V + + APE L A D WS G +Y++LT Sbjct 242 --ESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTG---- 295 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 + T+ ++ + +L P E L+K + A+ R Sbjct 296 -------ENRKKTIDKILKC-----KLNLPPYLTQEARDLLKKLLKRNAASR 335 Score = 154 bits (390), Expect = 3e-38, Method: Composition-based stats. Identities = 52/280 (19%), Positives = 99/280 (35%), Gaps = 33/280 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 ++ + L LG+G V++ R +V G+ + M + R+ Sbjct 84 EKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKVLKKAMIVRNAK------- 135 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 D +H E H + + G + ++ EY+ G L + L R Sbjct 136 ---DTAHTKAERNILEEV------KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER 186 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 E G +++ AL +L K +++ ++ NI+L G +KL+D G Sbjct 187 E-GIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-------HVKLTDFG 238 Query 762 VGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + ++ I ++APE L + + A+D W GA + ++ G P Sbjct 239 LCKESIHDGTVTHTFCGTIEYMAPEILM--RSGHNRAVDWWSLGALMYDML-TGAPPFTG 295 Query 818 RSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQR 856 + + + LP + L + L R Sbjct 296 ENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASR 335 >sp|P32491|MKK2_YEAST MAP kinase kinase MKK2/SSP33 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MKK2 PE=1 SV=2 Length=506 Score = 210 bits (534), Expect = 4e-57, Method: Composition-based stats. Identities = 82/392 (21%), Positives = 155/392 (40%), Gaps = 24/392 (6%) Query 782 ECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPSCPQL 841 E G + LS T E+ AP+ ++ + F ++ PE Sbjct 104 EYRVAGDSQLSERFSNLHVDITYKELLSS--APISTKLSNIDTTFIKKDLDTPEGEDSYP 161 Query 842 ATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIR 901 +TL S Y+ + S L + NL V+ + K + + Sbjct 162 STLLSA---YDFSSSGSNSAPLSANNIISCSNLIQGKDVDQLEEEAWRFGHLKDEITTLG 218 Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALK-ADCGPQHRSGWKQEIDILRTLYHEHII 960 LGEG G V+ ++ A+K + + P+++ +E+ ++ ++I+ Sbjct 219 ILGEGAGGSVA----KCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIV 274 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSL----RDYLPRH-SIGLAQLLLFAQQICEGMAYLH 1015 +Y G D+ S+ + MEY+ SL ++ L R I + A+ + G++YLH Sbjct 275 QYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLH 334 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 + IHRD+ +N+LL+ +K+ DFG++ G + F+ APE ++ Sbjct 335 ERKVIHRDIKPQNILLNEKGEIKLCDFGVS-----GEAVNSLAMTFTGTSFYMAPERIQG 389 Query 1076 YKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLP 1135 + DVWS G+TL E+ +S K + + + +L + L+ L Sbjct 390 QPYSVTCDVWSLGLTLLEVAGGRFPFES--DKITQNVAPIELLTMILTFSPQLKDEPELD 447 Query 1136 RPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + C + +A RP+ ++ Sbjct 448 I--SWSKTFRSFIDYCLKKDARERPSPRQMLK 477 Score = 169 bits (428), Expect = 2e-43, Method: Composition-based stats. Identities = 61/322 (19%), Positives = 105/322 (33%), Gaps = 56/322 (17%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + EIT L LG+G +V + RL+ LK ++ Sbjct 211 KDEITTLGILGEGAGGSVAKCRLKNGKKVF------------------------ALKTIN 246 Query 646 --PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRG--PENIMVTEYVEHGPL---DVW 698 + + + ++ +G+ + EY+ L Sbjct 247 TMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKN 306 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 L + G + +A+ + LSYL + ++H ++ +NILL G IKL Sbjct 307 LLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGE-------IKLC 359 Query 759 DPGVGLGALSR--EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPL- 815 D GV A++ ++APE + G S D W G TLLE+ G P Sbjct 360 DFGVSGEAVNSLAMTFTGTSFYMAPERIQG--QPYSVTCDVWSLGLTLLEVA-GGRFPFE 416 Query 816 -----QSRSPSEKEHFY-------QRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTIL 863 Q+ +P E + + L + CL + +RPS R +L Sbjct 417 SDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQML 476 Query 864 RDLTRLQPHNLADVLTVNPDSP 885 + + + Sbjct 477 KHPWIVGQMKKKVNMERFVKKC 498 >sp|Q8C0X8|SMKX_MOUSE Sperm motility kinase X OS=Mus musculus OX=10090 PE=2 SV=1 Length=640 Score = 213 bits (542), Expect = 4e-57, Method: Composition-based stats. Identities = 65/272 (24%), Positives = 113/272 (42%), Gaps = 31/272 (11%) Query 896 YLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLY 955 + + + LG+G FG+V L ++ T VA+K L EI+I+++L Sbjct 23 HYEILTTLGQGTFGEVKL----ASHLVTQTKVAIKILPKSRKNSLVQP---EIEIMKSLD 75 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYL 1014 H HIIK +++ +V+E+ G L + + + +Q+ + Y Sbjct 76 HPHIIKLLHII--DTTRNIFIVLEHAVGGELMSRIEEFGYLAEVECHRLFKQLVYALQYC 133 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H + +HRDL N+LLD+ VK+ DFGL + G + + + APE + Sbjct 134 HEKGIVHRDLKPENILLDHRGNVKLTDFGLGTKIIMGQKLVT----FCGTLPYCAPELFE 189 Query 1075 EYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGER 1133 + + A+DVWS GV LY + T C + ++ IA + Sbjct 190 DRGYDGRATDVWSLGVVLYFMATGCLPFNGYSYEAIKQKIIA----------------GK 233 Query 1134 LPRPDKCPCEVYHLMKNCWETEASFRPTFENL 1165 PR E++ ++ RPT ++ Sbjct 234 YPRSFSLSPELWEVIAKLLTVNPGERPTVHDI 265 Score = 175 bits (444), Expect = 1e-44, Method: Composition-based stats. Identities = 58/285 (20%), Positives = 100/285 (35%), Gaps = 38/285 (13%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 + L+ LGQGT V + +V +K+L Sbjct 21 TEHYEILTTLGQGTFGEV------------------------KLASHLVTQTKVAIKILP 56 Query 646 PSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGH 705 S + + +M + H H+ + + +V E+ G L + E G+ Sbjct 57 KSRKNSLVQ--PEIEIMKSLDHPHIIKLLHIIDTTRNIFIVLEHAVGGELMSRI-EEFGY 113 Query 706 VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG 765 + + +QL AL Y K +VH ++ NILL G +KL+D G+G Sbjct 114 LAEVECHRLFKQLVYALQYCHEKGIVHRDLKPENILLDHRG-------NVKLTDFGLGTK 166 Query 766 ALSREERV---ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSE 822 + ++ V +P+ APE A D W G L + + Sbjct 167 IIMGQKLVTFCGTLPYCAPELFEDRGYD-GRATDVWSLGVVLYFMATGCLPFNGYSYEAI 225 Query 823 KEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 K+ ++ P+L + ++ LT P +RP+ I R Sbjct 226 KQKIIAGKYPRSFSLSPELWEVIAKLLTVNPGERPTVHDIARFKW 270 >sp|Q9P419|HOG1_EMENI Mitogen-activated protein kinase hog1 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=hog1 PE=1 SV=1 Length=379 Score = 206 bits (523), Expect = 4e-57, Method: Composition-based stats. Identities = 70/294 (24%), Positives = 110/294 (37%), Gaps = 43/294 (15%) Query 901 RDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-KADCGPQHRSGWKQEIDILRTLYHEHI 959 + +G G FG V + T + VAVK + K P +E+ +L+ L HE+I Sbjct 24 QPVGMGAFGLVC----SARDQLTAQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENI 79 Query 960 IKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 I E + V E + L + + + F QI G+ Y+H+ Sbjct 80 ISLSDIFISPLED-IYFVTELL-GTDLHRLISSRPLEKQFIQYFLYQIMRGLKYVHSAGV 137 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE-YKF 1078 +HRDL N+L++ + +KI DFGLA+ Y S ++ APE + K+ Sbjct 138 VHRDLKPSNILINENCDLKICDFGLARIQDPQMTGY------VSTRYYRAPEIMLTWQKY 191 Query 1079 YYASDVWSFGVTLYELLTHCDSSQ----------------SPPTKFLELIGIAQGQMTVL 1122 DVWS E+L +PP ++ I V Sbjct 192 DAKVDVWSAACIFAEMLLGAPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVK 251 Query 1123 RLTELLERGE-RLPR------PDKCPCE------VYHLMKNCWETEASFRPTFE 1163 L + + +LP+ PDK P E +L+K R + E Sbjct 252 SLPKREPQDLAKLPKFLALVHPDKKPEEDEDYKNTINLLKAMLVYNPKDRISAE 305 Score = 132 bits (332), Expect = 7e-32, Method: Composition-based stats. Identities = 46/334 (14%), Positives = 96/334 (29%), Gaps = 23/334 (7%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 +E R G + RD+ V +K ++ P ++ Y Sbjct 10 FGTTFEITSRYTDLQPVGMGAF---GLVCSARDQLTAQPVAVKKIMKPFSTPVLSKRTYR 66 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H ++ + + + + VTE + L + + + Sbjct 67 ELKLLKHLRHENIISLSDIFISPLEDIYFVTELL-GTDLHRLISSR--PLEKQFIQYFLY 123 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + +VH ++ NIL+ + +K+ D G+ V Sbjct 124 QIMRGLKYVHSAGVVHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 176 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPE 835 + APE + +D W E+ ++ + P+ Sbjct 177 RYYRAPE-IMLTWQKYDAKVDVWSAACIFAEMLLGAPLFPGKDHVNQFSIITELLGTPPD 235 Query 836 PSCPQLA-TLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHK 894 + T + + P + P L L + + + + Sbjct 236 DVIQTICSENTLRFVKSLPKREPQDLAKLPKFLALVHPDKKPEEDEDYKNTINLLKAMLV 295 Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVA 928 K ++ P +D T E VA Sbjct 296 YNPKDRISAEA----ALAAPYLAPYHDETDEPVA 325 >sp|P21708|MK03_RAT Mitogen-activated protein kinase 3 OS=Rattus norvegicus OX=10116 GN=Mapk3 PE=1 SV=5 Length=380 Score = 206 bits (523), Expect = 4e-57, Method: Composition-based stats. Identities = 62/301 (21%), Positives = 119/301 (40%), Gaps = 26/301 (9%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 +++ +GEG +G VS + VA+K + + +EI IL Sbjct 41 PRYTQLQYIGEGAYGMVS----SAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRF 96 Query 955 YHEHIIKYKGCCEDQG---EKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011 HE++I + + + +V + + L L + + F QI G+ Sbjct 97 RHENVIGIRDILRAPTLEAMRDVYIVQDLME-TDLYKLLKSQQLSNDHICYFLYQILRGL 155 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 Y+H+ + +HRDL N+L++ +KI DFGLA+ H++ + + ++ APE Sbjct 156 KYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPE 215 Query 1072 C-LKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGI--AQGQMTVLRLTE 1126 L + + D+WS G L E+L++ + + ++GI + Q + + Sbjct 216 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 275 Query 1127 LLERGERLPRP-----------DKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVH 1173 + R P K + L+ + R T E + P L+ + Sbjct 276 MKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYY 335 Query 1174 E 1174 + Sbjct 336 D 336 Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats. Identities = 38/250 (15%), Positives = 82/250 (33%), Gaps = 48/250 (19%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 TQL ++G+G V D ++ RV +K + P H Sbjct 44 TQLQYIGEGAYGMV------------------------SSAYDHVRKTRVAIKKISPFEH 79 Query 650 DIA-LAFYETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDVWLRRER 703 ++ + H ++ + + + +V + +E L L+ + Sbjct 80 QTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLME-TDLYKLLKSQ- 137 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + Q+ L Y+ + N++H ++ N+L+ T+ +K+ D G+ Sbjct 138 -QLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLIN-------TTCDLKICDFGLA 189 Query 764 LGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 A + + APE + + + ++D W G L E+ + Sbjct 190 RIADPEHDHTGFLTEYVATRWYRAPE-IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPG 248 Query 817 SRSPSEKEHF 826 + H Sbjct 249 KHYLDQLNHI 258 >sp|Q63844|MK03_MOUSE Mitogen-activated protein kinase 3 OS=Mus musculus OX=10090 GN=Mapk3 PE=1 SV=5 Length=380 Score = 206 bits (523), Expect = 4e-57, Method: Composition-based stats. Identities = 62/301 (21%), Positives = 119/301 (40%), Gaps = 26/301 (9%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 +++ +GEG +G VS + VA+K + + +EI IL Sbjct 41 PRYTQLQYIGEGAYGMVS----SAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRF 96 Query 955 YHEHIIKYKGCCEDQG---EKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011 HE++I + + + +V + + L L + + F QI G+ Sbjct 97 RHENVIGIRDILRAPTLEAMRDVYIVQDLME-TDLYKLLKSQQLSNDHICYFLYQILRGL 155 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 Y+H+ + +HRDL N+L++ +KI DFGLA+ H++ + + ++ APE Sbjct 156 KYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPE 215 Query 1072 C-LKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGI--AQGQMTVLRLTE 1126 L + + D+WS G L E+L++ + + ++GI + Q + + Sbjct 216 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 275 Query 1127 LLERGERLPRP-----------DKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVH 1173 + R P K + L+ + R T E + P L+ + Sbjct 276 MKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYY 335 Query 1174 E 1174 + Sbjct 336 D 336 Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats. Identities = 38/250 (15%), Positives = 82/250 (33%), Gaps = 48/250 (19%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 TQL ++G+G V D ++ RV +K + P H Sbjct 44 TQLQYIGEGAYGMV------------------------SSAYDHVRKTRVAIKKISPFEH 79 Query 650 DIA-LAFYETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDVWLRRER 703 ++ + H ++ + + + +V + +E L L+ + Sbjct 80 QTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLME-TDLYKLLKSQ- 137 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + Q+ L Y+ + N++H ++ N+L+ T+ +K+ D G+ Sbjct 138 -QLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLIN-------TTCDLKICDFGLA 189 Query 764 LGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 A + + APE + + + ++D W G L E+ + Sbjct 190 RIADPEHDHTGFLTEYVATRWYRAPE-IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPG 248 Query 817 SRSPSEKEHF 826 + H Sbjct 249 KHYLDQLNHI 258 >sp|P24033|CDK1B_XENLA Cyclin-dependent kinase 1-B OS=Xenopus laevis OX=8355 GN=cdk1-b PE=1 SV=2 Length=302 Score = 203 bits (516), Expect = 4e-57, Method: Composition-based stats. Identities = 64/302 (21%), Positives = 117/302 (39%), Gaps = 31/302 (10%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 KI +GEG +G V Y + TG++VA+K ++ + + S +EI +L+ Sbjct 1 MDEYTKIEKIGEGTYGVV----YKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPR----HSIGLAQLLLFAQQIC 1008 L H +I+ + L L+ E++ + L+ YL I + + QI Sbjct 57 ELQHPNIVCLLDVLMQ--DSRLYLIFEFLSM-DLKKYLDSIPSGQYIDTMLVKSYLYQIL 113 Query 1009 EGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 +G+ + H++ +HRDL +N+L+DN ++K+ DFGLA+A RV +++ Sbjct 114 QGIVFCHSRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGIP---VRVYTHEVVTLWYR 170 Query 1069 APECLKEY-KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTEL 1127 A E L ++ DVWS G E+ T + Sbjct 171 ASEVLLGSVRYSTPVDVWSVGTIFAEIATKKPLFHGDSEIDQLFRIFRSLGTPNNEVWPE 230 Query 1128 LE--RGERLPRP-----------DKCPCEVYHLMKNCWETEASFRPTFEN--LIPILKTV 1172 +E + + P + L+ + + R + L P + Sbjct 231 VESLQDYKNTFPKWKGGSLSSNVKNIDEDGLDLLSKMLVYDPAKRISARKAMLHPYFDDL 290 Query 1173 HE 1174 + Sbjct 291 DK 292 Score = 164 bits (414), Expect = 2e-43, Method: Composition-based stats. Identities = 44/267 (16%), Positives = 93/267 (35%), Gaps = 41/267 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 E T++ +G+GT VY+GR + G V +K Sbjct 1 MDEYTKIEKIGEGTYGVVYKGRHKATGQ------------------------VVAMKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-- 701 L+ + SL+ ++ H ++ + V ++ ++ E++ L +L Sbjct 37 LENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSM-DLKKYLDSIP 95 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 ++ Q+ + + ++ ++H ++ +N+L+ G+ IKL+D G Sbjct 96 SGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDNKGV-------IKLADFG 148 Query 762 VGLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + V + + A E L G+ ST +D W G EI Sbjct 149 LARAFGIPVRVYTHEVVTLWYRASEVLL-GSVRYSTPVDVWSVGTIFAEIATKKPLFHGD 207 Query 818 RSPSEKEHFYQRQHRLPEPSCPQLATL 844 + ++ P++ +L Sbjct 208 SEIDQLFRIFRSLGTPNNEVWPEVESL 234 >sp|P53351|PLK2_MOUSE Serine/threonine-protein kinase PLK2 OS=Mus musculus OX=10090 GN=Plk2 PE=1 SV=1 Length=682 Score = 214 bits (545), Expect = 4e-57, Method: Composition-based stats. Identities = 73/320 (23%), Positives = 132/320 (41%), Gaps = 28/320 (9%) Query 850 TYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFG 909 P Q +T PH+ P+ + + + LG+G F Sbjct 32 KKRPQQPSEDGQPQAQVTPAAPHHHHHHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFA 91 Query 910 KVSLYCYDPTNDGTGEMVAVKALKAD--CGPQHRSGWKQEIDILRTLYHEHIIKYKGCCE 967 K CY+ T+ ++ A K + P R +EI++ R L+H+H++++ E Sbjct 92 K----CYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRLLHHKHVVQFYHYFE 147 Query 968 DQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAA 1026 D+ +++ +++EY S+ L R + ++ + +QI G+ YLH Q +HRDL Sbjct 148 DK--ENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKL 205 Query 1027 RNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWS 1086 N ++ +K+GDFGLA + +R R +P + +PE L + SD+W+ Sbjct 206 GNFFINEAMELKVGDFGLAARLEPLE--HRRRTICGTPN-YLSPEVLNKQGHGCESDIWA 262 Query 1087 FGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYH 1146 G +Y +L ++ T L+ T R R P H Sbjct 263 LGCVMYTMLLGRPPFET----------------TNLKETYRCIREARYTMPSSLLAPAKH 306 Query 1147 LMKNCWETEASFRPTFENLI 1166 L+ + RP+ +++I Sbjct 307 LIASMLSKNPEDRPSLDDII 326 Score = 154 bits (388), Expect = 3e-37, Method: Composition-based stats. Identities = 52/341 (15%), Positives = 101/341 (30%), Gaps = 38/341 (11%) Query 591 QLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHD 650 + LG+G YE + + K+ + R Sbjct 81 RGKVLGKGGFAKCYE--MTDLTNNKVYAAKIIPHSRVAKPHQR----------------- 121 Query 651 IALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAW 710 + L + H H+ + ++ EY + L+ R + Sbjct 122 --EKIDKEIELHRLLHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKA-RKVLTEPE 178 Query 711 KMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSRE 770 +Q+ S L YL + ++H ++ N + + +K+ D G+ E Sbjct 179 VRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINE-------AMELKVGDFGLAARLEPLE 231 Query 771 ER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH- 825 R +L+PE L D W G + + G P ++ + E Sbjct 232 HRRRTICGTPNYLSPEVL--NKQGHGCESDIWALGCVMYTMLL-GRPPFETTNLKETYRC 288 Query 826 FYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885 + ++ +P L + L+ P RPS I+R LQ + + + Sbjct 289 IREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTV 348 Query 886 ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEM 926 + K GK Y+ T++ + Sbjct 349 PDFHLSSPAKNFFKKAAAALFG-GKKDKARYNDTHNKVSKE 388 >sp|Q5BBL3|STE20_EMENI Serine/threonine-protein kinase ste20 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=ste20 PE=3 SV=1 Length=848 Score = 217 bits (552), Expect = 4e-57, Method: Composition-based stats. Identities = 56/271 (21%), Positives = 110/271 (41%), Gaps = 23/271 (8%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 + +G+G G V + T VA+K + D P+ + EI +++ H Sbjct 567 YYNLNKIGQGASGGV----FTAYEQHTNNCVAIKQMNLDLQPK-KDLIINEILVMKDSKH 621 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHA 1016 ++I+ + + L +VMEY+ GSL D + + + Q+ ++ G+ +LH+ Sbjct 622 KNIVNFLDSYLHGLD--LWVVMEYMEGGSLTDVVTFNIMSEPQIAAVCRETLNGLQHLHS 679 Query 1017 QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEY 1076 + IHRD+ + N+LL D +K+ DFG + ++ R +W APE + Sbjct 680 KGVIHRDIKSDNILLSLDGNIKLTDFGFCAQI---NDSQNKRNTMVGTPYWMAPEVVTRK 736 Query 1077 KFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPR 1136 ++ D+WS G+ E++ + + L IA ++ L + Sbjct 737 EYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLIATNGTPKIKDEHNLSPVFK--- 792 Query 1137 PDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + H + R + +L+ Sbjct 793 ------DFLHFALR---VDPEKRASAHDLLK 814 Score = 175 bits (443), Expect = 1e-43, Method: Composition-based stats. Identities = 52/293 (18%), Positives = 92/293 (31%), Gaps = 44/293 (15%) Query 592 LSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDI 651 L+ +GQG V+ ++ V +K ++ Sbjct 570 LNKIGQGASGGVF------------------------TAYEQHTNNCVAIKQMNLDLQPK 605 Query 652 ALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWK 711 +M H ++ + G + +V EY+E G L + + Sbjct 606 KDLIINEILVMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVV--TFNIMSEPQI 663 Query 712 MVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS--- 768 V ++ + L +L +K ++H ++ NILL+ IKL+D G Sbjct 664 AAVCRETLNGLQHLHSKGVIHRDIKSDNILLS-------LDGNIKLTDFGFCAQINDSQN 716 Query 769 -REERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFY 827 R V W+APE + +D W G +E+ +GE P + SP + Sbjct 717 KRNTMVGTPYWMAPEVVT--RKEYGRKVDIWSLGIMAIEMI-EGEPPYLTESPLRALYLI 773 Query 828 QRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLAD 876 P L +P +R S +L+ L Sbjct 774 ATNGTPKIKDEHNLSPVFKDFLHFALRVDPEKRASAHDLLKHPFMNLCAPLNH 826 >sp|Q15349|KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 OS=Homo sapiens OX=9606 GN=RPS6KA2 PE=1 SV=2 Length=733 Score = 215 bits (547), Expect = 4e-57, Method: Composition-based stats. Identities = 67/259 (26%), Positives = 109/259 (42%), Gaps = 24/259 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961 LG+G +GKV L G++ A+K LK + R K E DIL + H I+K Sbjct 65 LGQGSYGKVFLVR-KVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVK 123 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020 Q E L L+++++ G L L + + + ++ + +LH+ I Sbjct 124 LHYAF--QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGII 181 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 +RDL N+LLD + +KI DFGL+K E ++ + + + APE + Sbjct 182 YRDLKPENILLDEEGHIKITDFGLSK---EAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQ 238 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ++D WSFGV ++E+LT Q K T L +L P Sbjct 239 SADWWSFGVLMFEMLTGSLPFQGKDRKE----------------TMALILKAKLGMPQFL 282 Query 1141 PCEVYHLMKNCWETEASFR 1159 E L++ ++ R Sbjct 283 SGEAQSLLRALFKRNPCNR 301 Score = 191 bits (486), Expect = 2e-49, Method: Composition-based stats. Identities = 66/307 (21%), Positives = 106/307 (35%), Gaps = 37/307 (12%) Query 871 PHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK 930 +L V + + D+G G + + T+ AVK Sbjct 389 QQDLHKVPVHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATD----TEYAVK 444 Query 931 ALKADCGPQHRSGWKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDY 989 + + +EI+IL H +II K +D K + LVME + G L D Sbjct 445 IIDKS-----KRDPSEEIEILLRYGQHPNIITLKDVYDDG--KFVYLVMELMRGGELLDR 497 Query 990 LPRHS-IGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLL-DNDRL---VKIGDFGL 1044 + R + I + M YLH+Q +HRDL N+L D +++ DFG Sbjct 498 ILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGF 557 Query 1045 AKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSS--- 1101 AK + G+ + APE LK + A D+WS G+ LY +L Sbjct 558 AKQLRAGNGLLMT---PCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANG 614 Query 1102 -QSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRP 1160 P + L IG + ++ D ++ + R Sbjct 615 PDDTPEEILARIGSGKYALSGGNW-------------DSISDAAKDVVSKMLHVDPHQRL 661 Query 1161 TFENLIP 1167 T ++ Sbjct 662 TAMQVLK 668 Score = 174 bits (442), Expect = 9e-44, Method: Composition-based stats. Identities = 59/283 (21%), Positives = 108/283 (38%), Gaps = 39/283 (14%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 F + D + L LGQG+ V+ R V G D GQ Sbjct 51 FEKADPSQFELLKVLGQGSYGKVFLVR-------------------KVKGSDAGQ--LYA 89 Query 641 LKVLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVW 698 +KVL + + ++++V+H + +H + ++ +++ G L Sbjct 90 MKVLKKATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTR 149 Query 699 LRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLS 758 L +E K +A +LA AL +L + +++ ++ NILL G IK++ Sbjct 150 LSKEVMFTEEDVKFYLA-ELALALDHLHSLGIIYRDLKPENILLDEEG-------HIKIT 201 Query 759 DPGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAP 814 D G+ A+ ++R I ++APE + + + D W FG + E+ G P Sbjct 202 DFGLSKEAIDHDKRAYSFCGTIEYMAPEVV--NRRGHTQSADWWSFGVLMFEML-TGSLP 258 Query 815 LQSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQR 856 Q + E + +P+ + +L P R Sbjct 259 FQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPCNR 301 Score = 148 bits (374), Expect = 2e-35, Method: Composition-based stats. Identities = 47/267 (18%), Positives = 88/267 (33%), Gaps = 24/267 (9%) Query 632 DRGQELRVVLKVLDPSHHDIALAFYETASLMSQV-SHTHLAFVHGVCVRGPENIMVTEYV 690 + + +K++D S D + E ++ + H ++ + V G +V E + Sbjct 434 HKATDTEYAVKIIDKSKRDPS----EEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELM 489 Query 691 EHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEG 750 G L + R+R + V + + YL ++ +VH ++ NIL G Sbjct 490 RGGELLDRILRQR-YFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNIL---YRDESG 545 Query 751 TSPFIKLSDPGVGLGALSREERVERIPWL----APECLPGGANSLSTAMDKWGFGATLLE 806 + I++ D G + + + APE L A D W G L Sbjct 546 SPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLK--RQGYDAACDIWSLGILLYT 603 Query 807 ICFDGEAPL---QSRSPSEKEHFYQRQHRL-----PEPSCPQLATLTSQCLTYEPTQRPS 858 + G P +P E + + S+ L +P QR + Sbjct 604 MLA-GFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLT 662 Query 859 FRTILRDLTRLQPHNLADVLTVNPDSP 885 +L+ + L+ D Sbjct 663 AMQVLKHPWVVNREYLSPNQLSRQDVH 689 >sp|Q00534|CDK6_HUMAN Cyclin-dependent kinase 6 OS=Homo sapiens OX=9606 GN=CDK6 PE=1 SV=1 Length=326 Score = 204 bits (518), Expect = 4e-57, Method: Composition-based stats. Identities = 64/318 (20%), Positives = 122/318 (38%), Gaps = 36/318 (11%) Query 891 VFHKRYLKKIRDLGEGHFGKVSLYCYDPTN-DGTGEMVAVKALKADCGPQHRS-GWKQEI 948 + + + ++GEG +GKV + + G VA+K ++ G + +E+ Sbjct 7 CRADQQYECVAEIGEGAYGKV----FKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREV 62 Query 949 DILRTLY---HEHIIKYKGCCE---DQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQ 999 +LR L H ++++ C E L LV E+V L YL P + Sbjct 63 AVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQ-DLTTYLDKVPEPGVPTET 121 Query 1000 LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE 1059 + Q+ G+ +LH+ +HRDL +N+L+ + +K+ DFGLA+ + Sbjct 122 IKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIY----SFQMALT 177 Query 1060 DGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTKFLELIGI 1114 +++ APE L + + D+WS G E+ + K L++IG+ Sbjct 178 SVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGL 237 Query 1115 A--QGQMTVLRLTELLERGERLPRPDKCPCEV----YHLMKNCWETEASFRPTFENLI-- 1166 + + L + +K ++ L+ C + R + + + Sbjct 238 PGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSH 297 Query 1167 ---PILKTVHEKYQGQAP 1181 L+ E P Sbjct 298 PYFQDLERCKENLDSHLP 315 Score = 148 bits (374), Expect = 6e-38, Method: Composition-based stats. Identities = 45/229 (20%), Positives = 83/229 (36%), Gaps = 47/229 (21%) Query 594 HLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIAL 653 +G+G V++ R G V LK + + + Sbjct 18 EIGEGAYGKVFKARDLKNGGRF-----------------------VALKRVRVQTGEEGM 54 Query 654 AF--YETASLMSQVS---HTHLAFVHGVCV-----RGPENIMVTEYVEHGPLDVWLRR-E 702 +++ + H ++ + VC R + +V E+V+ L +L + Sbjct 55 PLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQ-DLTTYLDKVP 113 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 VP + QL L +L + +VH ++ +NIL+ G IKL+D G+ Sbjct 114 EPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQ-------IKLADFGL 166 Query 763 GL---GALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 ++ V + + APE L +S +T +D W G E+ Sbjct 167 ARIYSFQMALTSVVVTLWYRAPEVLLQ--SSYATPVDLWSVGCIFAEMF 213 >sp|P23443|KS6B1_HUMAN Ribosomal protein S6 kinase beta-1 OS=Homo sapiens OX=9606 GN=RPS6KB1 PE=1 SV=2 Length=525 Score = 210 bits (535), Expect = 4e-57, Method: Composition-based stats. Identities = 70/292 (24%), Positives = 115/292 (39%), Gaps = 26/292 (9%) Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931 + ++ S P + +R LG+G +GKV T TG++ A+K Sbjct 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKV 124 Query 932 LKADC---GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 LK + + K E +IL + H I+ + G+ L L++EY+ G L Sbjct 125 LKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGK--LYLILEYLSGGELFM 182 Query 989 YLPRHSIG-LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 L R I + +I + +LH + I+RDL N++L++ VK+ DFGL K Sbjct 183 QLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK- 241 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 E V + + APE L A D WS G +Y++LT Sbjct 242 --ESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTG---- 295 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 + T+ ++ + +L P E L+K + A+ R Sbjct 296 -------ENRKKTIDKILKC-----KLNLPPYLTQEARDLLKKLLKRNAASR 335 Score = 154 bits (390), Expect = 3e-38, Method: Composition-based stats. Identities = 52/280 (19%), Positives = 99/280 (35%), Gaps = 33/280 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 ++ + L LG+G V++ R +V G+ + M + R+ Sbjct 84 EKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKVLKKAMIVRNAK------- 135 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 D +H E H + + G + ++ EY+ G L + L R Sbjct 136 ---DTAHTKAERNILEEV------KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER 186 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 E G +++ AL +L K +++ ++ NI+L G +KL+D G Sbjct 187 E-GIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-------HVKLTDFG 238 Query 762 VGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + ++ I ++APE L + + A+D W GA + ++ G P Sbjct 239 LCKESIHDGTVTHTFCGTIEYMAPEILM--RSGHNRAVDWWSLGALMYDML-TGAPPFTG 295 Query 818 RSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQR 856 + + + LP + L + L R Sbjct 296 ENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASR 335 >sp|Q9LSC2|Y3589_ARATH PTI1-like tyrosine-protein kinase At3g15890 OS=Arabidopsis thaliana OX=3702 GN=At3g15890 PE=2 SV=1 Length=361 Score = 205 bits (521), Expect = 4e-57, Method: Composition-based stats. Identities = 69/282 (24%), Positives = 120/282 (43%), Gaps = 18/282 (6%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYH 956 LGEG FG V G +AVK LK + + + E++IL + H Sbjct 39 FNYDNKLGEGRFGSVYWGQL-----WDGSQIAVKRLK-EWSNREEIDFAVEVEILARIRH 92 Query 957 EHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-----IGLAQLLLFAQQICEGM 1011 ++++ +G C + E+ LV EY+ SL +L + + + A + + Sbjct 93 KNLLSVRGYCAEGQER--LLVYEYMQNLSLVSHLHGQHSAECLLDWTKRMKIAISSAQAI 150 Query 1012 AYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 AYLH H +H D+ A NVLLD++ ++ DFG K +P+ + S + Sbjct 151 AYLHDHATPHIVHGDVRASNVLLDSEFEARVTDFGYGKLMPDDDTGDGATK-AKSNNGYI 209 Query 1069 APECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSP-PTKFLELIGIAQGQMTVLRLTEL 1127 +PEC K SDV+SFG+ L L++ + PT + + E+ Sbjct 210 SPECDASGKESETSDVYSFGILLMVLVSGKRPLERLNPTTTRCITEWVLPLVYERNFGEI 269 Query 1128 LERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPIL 1169 +++ + +V + C +T+ RPT ++ +L Sbjct 270 VDKRLSEEHVAEKLKKVVLVGLMCAQTDPDKRPTMSEVVEML 311 Score = 177 bits (448), Expect = 2e-47, Method: Composition-based stats. Identities = 64/331 (19%), Positives = 119/331 (36%), Gaps = 66/331 (20%) Query 565 RGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDE 624 + + P S H + LG+G +VY G+L Sbjct 16 KKEKEEPSWRVFSLKELH-AATNSFNYDNKLGEGRFGSVYWGQLWDGS------------ 62 Query 625 DPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENI 684 ++ +K L + + F +++++ H +L V G C G E + Sbjct 63 -------------QIAVKRLKEWSNREEIDFAVEVEILARIRHKNLLSVRGYCAEGQERL 109 Query 685 MVTEYVEHGPLDVWLRRERGH---VPMAWKMVVAQQLASALSYLENK---NLVHGNVCGR 738 +V EY+++ L L + + +M +A A A++YL + ++VHG+V Sbjct 110 LVYEYMQNLSLVSHLHGQHSAECLLDWTKRMKIAISSAQAIAYLHDHATPHIVHGDVRAS 169 Query 739 NILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERI------PWLAPECLPGGANSLS 792 N+LL A +++D G G + +++PEC G S Sbjct 170 NVLLDSEFEA-------RVTDFGYGKLMPDDDTGDGATKAKSNNGYISPECDASGKE--S 220 Query 793 TAMDKWGFGATLLEICFDGEAPLQSRSPS--------------EKEHFYQRQHRLPEPS- 837 D + FG LL + G+ PL+ +P+ E+ RL E Sbjct 221 ETSDVYSFGI-LLMVLVSGKRPLERLNPTTTRCITEWVLPLVYERNFGEIVDKRLSEEHV 279 Query 838 ---CPQLATLTSQCLTYEPTQRPSFRTILRD 865 ++ + C +P +RP+ ++ Sbjct 280 AEKLKKVVLVGLMCAQTDPDKRPTMSEVVEM 310 >sp|Q38772|CDC2A_ANTMA Cell division control protein 2 homolog A OS=Antirrhinum majus OX=4151 GN=CDC2A PE=2 SV=2 Length=294 Score = 202 bits (515), Expect = 4e-57, Method: Composition-based stats. Identities = 76/294 (26%), Positives = 126/294 (43%), Gaps = 31/294 (11%) Query 894 KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR-SGWKQEIDILR 952 +K+ +GEG +G V Y + T E +A+K ++ + + S +EI +L+ Sbjct 1 MEQYEKVEKIGEGTYGVV----YKARDRVTNETIALKKIRLEQEDEGVPSTAIREISLLK 56 Query 953 TLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL---PRHSIGLAQLLLFAQQICE 1009 + H +I++ + EK L LV EY+ L L+ ++ P S + +F QI Sbjct 57 EMQHGNIVRLQDVV--HSEKRLYLVFEYLDL-DLKKHMDSCPEFSQDPRLVKMFLYQILR 113 Query 1010 GMAYLHAQHYIHRDLAARNVLLDNDRL-VKIGDFGLAKAVPEGHEYYRVREDGDSPVFWY 1068 G+AY H+ +HRDL +N+L+D +K+ DFGLA+A R +++ Sbjct 114 GIAYCHSHRVLHRDLKPQNLLIDRRTNALKLADFGLARAFGIP---VRTFTHEVVTLWYR 170 Query 1069 APECLKEYK-FYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIAQGQMTVL 1122 APE L + + DVWS G E++ DS K ++G + T Sbjct 171 APEILLGSRHYSTPVDVWSVGCIFAEMVNQRPLFPGDSEIDELFKIFRVMGTPNEE-TWP 229 Query 1123 RLTELLERGERLPR-PDKCPCEV--------YHLMKNCWETEASFRPTFENLIP 1167 +T L + P+ P K V L+ + S R T N + Sbjct 230 GVTSLPDFKSAFPKWPAKELAAVVPNLDASGLDLLDKMLRLDPSKRITARNALQ 283 Score = 163 bits (412), Expect = 3e-43, Method: Composition-based stats. Identities = 46/266 (17%), Positives = 92/266 (35%), Gaps = 39/266 (15%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK--V 643 ++ ++ +G+GT VY+ RDR + LK Sbjct 1 MEQYEKVEKIGEGTYGVVYKA------------------------RDRVTNETIALKKIR 36 Query 644 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR-E 702 L+ + SL+ ++ H ++ + V +V EY++ L + Sbjct 37 LEQEDEGVPSTAIREISLLKEMQHGNIVRLQDVVHSEKRLYLVFEYLDL-DLKKHMDSCP 95 Query 703 RGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + Q+ ++Y + ++H ++ +N+L+ R A +KL+D G+ Sbjct 96 EFSQDPRLVKMFLYQILRGIAYCHSHRVLHRDLKPQNLLIDRRTNA------LKLADFGL 149 Query 763 GLG----ALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSR 818 + V + + APE L G+ ST +D W G E+ Sbjct 150 ARAFGIPVRTFTHEVVTLWYRAPEILL-GSRHYSTPVDVWSVGCIFAEMVNQRPLFPGDS 208 Query 819 SPSEKEHFYQRQHRLPEPSCPQLATL 844 E ++ E + P + +L Sbjct 209 EIDELFKIFRVMGTPNEETWPGVTSL 234 >sp|P27361|MK03_HUMAN Mitogen-activated protein kinase 3 OS=Homo sapiens OX=9606 GN=MAPK3 PE=1 SV=4 Length=379 Score = 206 bits (523), Expect = 4e-57, Method: Composition-based stats. Identities = 62/301 (21%), Positives = 119/301 (40%), Gaps = 26/301 (9%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 +++ +GEG +G VS + VA+K + + +EI IL Sbjct 40 PRYTQLQYIGEGAYGMVS----SAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRF 95 Query 955 YHEHIIKYKGCCEDQG---EKSLQLVMEYVPLGSLRDYLPRHSIGLAQLLLFAQQICEGM 1011 HE++I + + + +V + + L L + + F QI G+ Sbjct 96 RHENVIGIRDILRASTLEAMRDVYIVQDLME-TDLYKLLKSQQLSNDHICYFLYQILRGL 154 Query 1012 AYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 Y+H+ + +HRDL N+L++ +KI DFGLA+ H++ + + ++ APE Sbjct 155 KYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPE 214 Query 1072 C-LKEYKFYYASDVWSFGVTLYELLTHCD--SSQSPPTKFLELIGI--AQGQMTVLRLTE 1126 L + + D+WS G L E+L++ + + ++GI + Q + + Sbjct 215 IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIIN 274 Query 1127 LLERGERLPRP-----------DKCPCEVYHLMKNCWETEASFRPTFENLI--PILKTVH 1173 + R P K + L+ + R T E + P L+ + Sbjct 275 MKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYY 334 Query 1174 E 1174 + Sbjct 335 D 335 Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats. Identities = 38/250 (15%), Positives = 82/250 (33%), Gaps = 48/250 (19%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 TQL ++G+G V D ++ RV +K + P H Sbjct 43 TQLQYIGEGAYGMV------------------------SSAYDHVRKTRVAIKKISPFEH 78 Query 650 DIA-LAFYETASLMSQVSHTHLAFVHGVCVRG-----PENIMVTEYVEHGPLDVWLRRER 703 ++ + H ++ + + + +V + +E L L+ + Sbjct 79 QTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLME-TDLYKLLKSQ- 136 Query 704 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG 763 + Q+ L Y+ + N++H ++ N+L+ T+ +K+ D G+ Sbjct 137 -QLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLIN-------TTCDLKICDFGLA 188 Query 764 LGALSREERVE-------RIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ 816 A + + APE + + + ++D W G L E+ + Sbjct 189 RIADPEHDHTGFLTEYVATRWYRAPE-IMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPG 247 Query 817 SRSPSEKEHF 826 + H Sbjct 248 KHYLDQLNHI 257 >sp|Q4FZD7|PLK5_MOUSE Inactive serine/threonine-protein kinase PLK5 OS=Mus musculus OX=10090 GN=Plk5 PE=1 SV=1 Length=595 Score = 212 bits (539), Expect = 4e-57, Method: Composition-based stats. Identities = 63/268 (24%), Positives = 111/268 (41%), Gaps = 28/268 (10%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC--GPQHRSGWKQEIDILRTLYHEHII 960 +G+G F + CY T+ T + A+K + + R ++EI + L H +I+ Sbjct 33 IGKGAFSR----CYKLTDMSTSAVFALKVVPRGGAGRLRLRGKVEREIALHSRLRHRNIV 88 Query 961 KYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-RHSIGLAQLLLFAQQICEGMAYLHAQHY 1019 + D+ + +V+EY SL L R ++ ++ + + + G+ YLH Q Sbjct 89 AFHAHFADRDH--VYMVLEYCSRQSLAHVLKVRRTLTEPEVRYYLRGLVSGLRYLHQQRI 146 Query 1020 IHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFY 1079 +HRDL N L+ + VKIGD GLA V +RV + APE + Sbjct 147 VHRDLKPSNFFLNKNMEVKIGDLGLAARVGPAGRCHRV---LCGTPNFQAPEVVSRNGHS 203 Query 1080 YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDK 1139 SD+W+ G +Y +LT + P + + + + G L P Sbjct 204 CKSDIWALGCIMYTVLTGTPPFAAAP---------------LSEMYQNIRDGHYLE-PTH 247 Query 1140 CPCEVYHLMKNCWETEASFRPTFENLIP 1167 L+ + + RP+ ++L+ Sbjct 248 LSPSARSLIARLLAPDPAERPSLDHLLQ 275 Score = 160 bits (406), Expect = 6e-40, Method: Composition-based stats. Identities = 62/309 (20%), Positives = 103/309 (33%), Gaps = 37/309 (12%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 + +G+G + Y+ L + K+ R RG+ Sbjct 28 RRGKLIGKGAFSRCYK--LTDMSTSAVFALKVVPRGGAGRLRLRGKVE------------ 73 Query 650 DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMA 709 +L S++ H ++ H MV EY L L+ R + Sbjct 74 -------REIALHSRLRHRNIVAFHAHFADRDHVYMVLEYCSRQSLAHVLKVRR-TLTEP 125 Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG--LGAL 767 + L S L YL + +VH ++ N L + + +K+ D G+ +G Sbjct 126 EVRYYLRGLVSGLRYLHQQRIVHRDLKPSNFFLNK-------NMEVKIGDLGLAARVGPA 178 Query 768 SREERV--ERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEH 825 R RV + APE + N S D W G + + G P + SE Sbjct 179 GRCHRVLCGTPNFQAPEVVS--RNGHSCKSDIWALGCIMYTVL-TGTPPFAAAPLSEMYQ 235 Query 826 FYQRQHRL-PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884 + H L P P +L ++ L +P +RPS +L+D Q + + S Sbjct 236 NIRDGHYLEPTHLSPSARSLIARLLAPDPAERPSLDHLLQDDFFSQGFTPERLPPHSCHS 295 Query 885 PASDPTVFH 893 P Sbjct 296 PPVFAFPPP 304 >sp|P67999|KS6B1_RAT Ribosomal protein S6 kinase beta-1 OS=Rattus norvegicus OX=10116 GN=Rps6kb1 PE=1 SV=1 Length=525 Score = 210 bits (534), Expect = 4e-57, Method: Composition-based stats. Identities = 70/292 (24%), Positives = 115/292 (39%), Gaps = 26/292 (9%) Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931 + ++ S P + +R LG+G +GKV T TG++ A+K Sbjct 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKV 124 Query 932 LKADC---GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 LK + + K E +IL + H I+ + G+ L L++EY+ G L Sbjct 125 LKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGK--LYLILEYLSGGELFM 182 Query 989 YLPRHSIG-LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 L R I + +I + +LH + I+RDL N++L++ VK+ DFGL K Sbjct 183 QLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK- 241 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 E V + + APE L A D WS G +Y++LT Sbjct 242 --ESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTG---- 295 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 + T+ ++ + +L P E L+K + A+ R Sbjct 296 -------ENRKKTIDKILKC-----KLNLPPYLTQEARDLLKKLLKRNAASR 335 Score = 154 bits (390), Expect = 3e-38, Method: Composition-based stats. Identities = 52/280 (19%), Positives = 99/280 (35%), Gaps = 33/280 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 ++ + L LG+G V++ R +V G+ + M + R+ Sbjct 84 EKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKVLKKAMIVRNAK------- 135 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 D +H E H + + G + ++ EY+ G L + L R Sbjct 136 ---DTAHTKAERNILEEV------KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER 186 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 E G +++ AL +L K +++ ++ NI+L G +KL+D G Sbjct 187 E-GIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-------HVKLTDFG 238 Query 762 VGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + ++ I ++APE L + + A+D W GA + ++ G P Sbjct 239 LCKESIHDGTVTHTFCGTIEYMAPEILM--RSGHNRAVDWWSLGALMYDML-TGAPPFTG 295 Query 818 RSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQR 856 + + + LP + L + L R Sbjct 296 ENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASR 335 >sp|O93982|HOG1_ZYGRC Mitogen-activated protein kinase HOG1 OS=Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229) OX=559307 GN=HOG1 PE=3 SV=2 Length=431 Score = 207 bits (527), Expect = 4e-57, Method: Composition-based stats. Identities = 65/319 (20%), Positives = 111/319 (35%), Gaps = 31/319 (10%) Query 875 ADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKAL-K 933 + + +G G FG V T+ G+ VA+K + K Sbjct 1 MATHEEFIRTQVFGTVFEITNRYTDLNPVGMGAFGLVC----SATDTLAGQPVAIKKIMK 56 Query 934 ADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRH 993 +E+ +L+ L HE++I + E + V E L L Sbjct 57 PFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLED-IYFVTEL-QGTDLHRLLQTR 114 Query 994 SIGLAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053 + + F QI G+ Y+H+ IHRDL N+L++ + +KI DFGLA+ Sbjct 115 PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARIQDPQMT 174 Query 1054 YYRVREDGDSPVFWYAPECLKE-YKFYYASDVWSFGVTLYELLTHCDSSQ-----SPPTK 1107 Y S ++ APE + K+ D+WS G E++ + Sbjct 175 GY------VSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFSEMIEGKPLFPGKDHVHQFSI 228 Query 1108 FLELIGIAQGQMTVLRLTELLER-----GERLPRP-----DKCPCEVYHLMKNCWETEAS 1157 +L+G + +E + R P P + L++ + Sbjct 229 ITDLLGSPPRDVINTICSENTLKFVTSLPHRDPVPFQERFKTVEPDAVDLLERMLVFDPK 288 Query 1158 FRPTFEN--LIPILKTVHE 1174 R T + + P L H+ Sbjct 289 KRITAADALVHPYLAPYHD 307 Score = 135 bits (340), Expect = 1e-32, Method: Composition-based stats. Identities = 36/213 (17%), Positives = 69/213 (32%), Gaps = 18/213 (8%) Query 600 RTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLDPSHHD-IALAFYE 657 V+E R G + D V +K ++ P +A Y Sbjct 13 FGTVFEITNRYTDLNPVGMGAF---GLVCSATDTLAGQPVAIKKIMKPFSTAVLAKRTYR 69 Query 658 TASLMSQVSHTHLAFVHGVCVRG-PENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQ 716 L+ + H +L + + + + VTE + L L+ + + Sbjct 70 ELKLLKHLRHENLICLQDIFLSPLEDIYFVTEL-QGTDLHRLLQTR--PLEKQFVQYFLY 126 Query 717 QLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL-GALSREERVER 775 Q+ L Y+ + ++H ++ NIL+ + +K+ D G+ V Sbjct 127 QILRGLKYVHSAGVIHRDLKPSNILINE-------NCDLKICDFGLARIQDPQMTGYVST 179 Query 776 IPWLAPECLPGGANSLSTAMDKWGFGATLLEIC 808 + APE + +D W G E+ Sbjct 180 RYYRAPE-IMLTWQKYDVEVDIWSAGCIFSEMI 211 >sp|Q8GXQ3|WAKLF_ARATH Wall-associated receptor kinase-like 6 OS=Arabidopsis thaliana OX=3702 GN=WAKL6 PE=2 SV=2 Length=642 Score = 213 bits (542), Expect = 4e-57, Method: Composition-based stats. Identities = 57/269 (21%), Positives = 94/269 (35%), Gaps = 50/269 (19%) Query 558 TSNLIIMRGARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPE 617 LI G R + +L + LGQG + VY+G L Sbjct 404 KQQLITKNGNVDMSRIFSSKELKK---ATDNFSMNRVLGQGGQGTVYKGMLAEGRI---- 456 Query 618 EGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVC 677 V +K F L+SQ++H ++ + G C Sbjct 457 ---------------------VAVKRSKVVGEGKMEEFINEVVLLSQINHRNIVKLLGCC 495 Query 678 VRGPENIMVTEYVEHGPLDVWLR--RERGHVPMAW--KMVVAQQLASALSYLENK---NL 730 + ++V EY+ +G L L E M W ++ +A ++A ALSY+ + + Sbjct 496 LETEVPVLVYEYIPNGDLFKRLHEKSESNDYTMTWEVRLRIAIEIAGALSYMHSAASIPI 555 Query 731 VHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER-----VERIPWLAPECLP 785 H ++ NILL A K+SD G + ++ PE Sbjct 556 YHRDIKTTNILLDEKYRA-------KVSDFGTSRSITIAQTHLTTLVAGTFGYMDPEYFL 608 Query 786 GGANSLSTAMDKWGFGATLLEICFDGEAP 814 ++ + D + FG L+E+ GE P Sbjct 609 --SSQYTDKSDVYSFGVVLVELI-TGEKP 634 Score = 212 bits (540), Expect = 9e-57, Method: Composition-based stats. Identities = 59/215 (27%), Positives = 90/215 (42%), Gaps = 19/215 (9%) Query 895 RYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTL 954 R LG+G G V G +VAVK K G + E+ +L + Sbjct 430 DNFSMNRVLGQGGQGTVYKGML-----AEGRIVAVKRSKV-VGEGKMEEFINEVVLLSQI 483 Query 955 YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS------IGLAQLLLFAQQIC 1008 H +I+K GCC + + LV EY+P G L L S + L A +I Sbjct 484 NHRNIVKLLGCCLET--EVPVLVYEYIPNGDLFKRLHEKSESNDYTMTWEVRLRIAIEIA 541 Query 1009 EGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV 1065 ++Y+H+ HRD+ N+LLD K+ DFG ++++ + + Sbjct 542 GALSYMHSAASIPIYHRDIKTTNILLDEKYRAKVSDFGTSRSITIAQTH--LTTLVAGTF 599 Query 1066 FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDS 1100 + PE ++ SDV+SFGV L EL+T Sbjct 600 GYMDPEYFLSSQYTDKSDVYSFGVVLVELITGEKP 634 >sp|Q6TJY3|KS6B1_BOVIN Ribosomal protein S6 kinase beta-1 OS=Bos taurus OX=9913 GN=RPS6KB1 PE=2 SV=1 Length=527 Score = 210 bits (534), Expect = 5e-57, Method: Composition-based stats. Identities = 70/292 (24%), Positives = 115/292 (39%), Gaps = 26/292 (9%) Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931 + ++ S P + +R LG+G +GKV T TG++ A+K Sbjct 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKV 124 Query 932 LKADC---GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 LK + + K E +IL + H I+ + G+ L L++EY+ G L Sbjct 125 LKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGK--LYLILEYLSGGELFM 182 Query 989 YLPRHSIG-LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 L R I + +I + +LH + I+RDL N++L++ VK+ DFGL K Sbjct 183 QLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK- 241 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 E V + + APE L A D WS G +Y++LT Sbjct 242 --ESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTG---- 295 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 + T+ ++ + +L P E L+K + A+ R Sbjct 296 -------ENRKKTIDKILKC-----KLNLPPYLTQEARDLLKKLLKRNAASR 335 Score = 154 bits (390), Expect = 3e-38, Method: Composition-based stats. Identities = 52/280 (19%), Positives = 99/280 (35%), Gaps = 33/280 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 ++ + L LG+G V++ R +V G+ + M + R+ Sbjct 84 EKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKVLKKAMIVRNAK------- 135 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 D +H E H + + G + ++ EY+ G L + L R Sbjct 136 ---DTAHTKAERNILEEV------KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER 186 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 E G +++ AL +L K +++ ++ NI+L G +KL+D G Sbjct 187 E-GIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-------HVKLTDFG 238 Query 762 VGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + ++ I ++APE L + + A+D W GA + ++ G P Sbjct 239 LCKESIHDGTVTHTFCGTIEYMAPEILM--RSGHNRAVDWWSLGALMYDML-TGAPPFTG 295 Query 818 RSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQR 856 + + + LP + L + L R Sbjct 296 ENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASR 335 >sp|Q55CZ1|GDT2_DICDI Probable serine/threonine-protein kinase gdt2 OS=Dictyostelium discoideum OX=44689 GN=gdt2 PE=2 SV=1 Length=1637 Score = 221 bits (562), Expect = 5e-57, Method: Composition-based stats. Identities = 85/348 (24%), Positives = 145/348 (42%), Gaps = 40/348 (11%) Query 839 PQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLK 898 P + T S +T T + + + I+R T + + + + +S ++ F++ +K Sbjct 1234 PNVETSISLSVTLFSTTKYNEKVIVRFETLDVKQSWSTFVFLRLESELTNIIDFNEIIIK 1293 Query 899 KIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEH 958 + EG FG V + + VAVK LK + ++EI +L L H + Sbjct 1294 NY--ISEGTFGIVYRGIWRSS------PVAVKLLKNEYVDHD--EIEKEISLLERLRHPN 1343 Query 959 IIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP--RHSIGLAQLLLFAQQICEGMAYLHA 1016 I+ Y G G +V +Y G L Y+ ++ I + Q + I + AYLH Sbjct 1344 ILLYVGRFIFSGIHG--IVTDYCSKGCLSKYIHENKYKITIIQKIRILIDISKACAYLHR 1401 Query 1017 QHYIHRDLAARNVLLDNDR-----LVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPE 1071 HRDL N+L+ + K+ DFG +K E + R V + + E Sbjct 1402 NGITHRDLKPENILITSLNPKSLVCAKVSDFGTSKETNERYNLQTRR----GTVAYMSNE 1457 Query 1072 CLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERG 1131 L + + ++D++SFG+ YEL + S P R+ EL+ + Sbjct 1458 ILSQGSYTKSTDIYSFGMLCYELFSERIPYYSEPH---------------WRIRELVLKN 1502 Query 1132 ERLPRPDKC--PCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQ 1177 ER + ++ ++ CW S RPTF+ L LK + +KY Sbjct 1503 ERPSLDQEIFKDTDISDIVTRCWSKNPSQRPTFDYLSKYLKHLLKKYD 1550 Score = 201 bits (511), Expect = 6e-51, Method: Composition-based stats. Identities = 56/307 (18%), Positives = 114/307 (37%), Gaps = 39/307 (13%) Query 581 FHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVV 640 + +D EI +++ +GT VY G R V Sbjct 1282 TNIIDFNEIIIKNYISEGTFGIVYRGIWRSS--------------------------PVA 1315 Query 641 LKVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR 700 +K+L + D + SL+ ++ H ++ G + + +VT+Y G L ++ Sbjct 1316 VKLLKNEYVD-HDEIEKEISLLERLRHPNILLYVGRFIFSGIHGIVTDYCSKGCLSKYIH 1374 Query 701 RERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDP 760 + + + K+ + ++ A +YL + H ++ NIL+ L + K+SD Sbjct 1375 ENKYKITIIQKIRILIDISKACAYLHRNGITHRDLKPENILITSLN--PKSLVCAKVSDF 1432 Query 761 GVGLGALSR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 G R + R + +++ E L G S + + D + FG E+ + P S Sbjct 1433 GTSKETNERYNLQTRRGTVAYMSNEILSQG--SYTKSTDIYSFGMLCYELFSE-RIPYYS 1489 Query 818 RSPSEKEHFYQRQHRL----PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHN 873 + R ++ + ++C + P+QRP+F + + L L Sbjct 1490 EPHWRIRELVLKNERPSLDQEIFKDTDISDIVTRCWSKNPSQRPTFDYLSKYLKHLLKKY 1549 Query 874 LADVLTV 880 + + Sbjct 1550 DINNIIY 1556 >sp|Q90XC2|NEK8_DANRE Serine/threonine-protein kinase Nek8 OS=Danio rerio OX=7955 GN=nek8 PE=2 SV=1 Length=697 Score = 214 bits (545), Expect = 5e-57, Method: Composition-based stats. Identities = 69/269 (26%), Positives = 117/269 (43%), Gaps = 30/269 (11%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAD-CGPQHRSGWKQEIDILRTLYHEHIIK 961 +G G FG V L +V +K + + R + E +L+ L H +II+ Sbjct 10 VGRGAFGIVHLC----RRRTDSALVILKEIPVEQMTRDERLAAQNECQVLKLLSHPNIIE 65 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS---IGLAQLLLFAQQICEGMAYLHAQH 1018 Y + +K+L + MEY P G+L DY+ + + +L QI + ++H + Sbjct 66 YYENFLE--DKALMIAMEYAPGGTLADYIQKRCNSLLDEDTILHSFVQILLALYHVHNKL 123 Query 1019 YIHRDLAARNVLLDND-RLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYK 1077 +HRDL +N+LLD +VKIGDFG++K + + Y V + +PE + Sbjct 124 ILHRDLKTQNILLDKHQMIVKIGDFGISKILVSKSKAYTV----VGTPCYISPELCEGKP 179 Query 1078 FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRP 1137 + SD+W+ G LYEL + + ++ L L + G P Sbjct 180 YNQKSDIWALGCVLYELASLKRAFEAANLPALVL---------------KIMSGTFAPIS 224 Query 1138 DKCPCEVYHLMKNCWETEASFRPTFENLI 1166 D+ E+ L+ N + S RP ++ Sbjct 225 DRYSPELRQLILNMLNLDPSKRPQLNEIM 253 Score = 169 bits (428), Expect = 3e-42, Method: Composition-based stats. Identities = 51/293 (17%), Positives = 106/293 (36%), Gaps = 39/293 (13%) Query 586 QKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLD 645 ++ + +G+G V+ R R + + V+LK + Sbjct 1 MEKYEKTKVVGRGAFGIVHLCRRRTDSA------------------------LVILKEIP 36 Query 646 PSHH--DIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER 703 D LA ++ +SH ++ + + ++ EY G L ++++ Sbjct 37 VEQMTRDERLAAQNECQVLKLLSHPNIIEYYENFLEDKALMIAMEYAPGGTLADYIQKRC 96 Query 704 GH-VPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGV 762 + + Q+ AL ++ NK ++H ++ +NILL + +K+ D G+ Sbjct 97 NSLLDEDTILHSFVQILLALYHVHNKLILHRDLKTQNILLDKH------QMIVKIGDFGI 150 Query 763 GLGALSRE---ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRS 819 +S+ V +++PE G + D W G L E+ A + Sbjct 151 SKILVSKSKAYTVVGTPCYISPELCEG--KPYNQKSDIWALGCVLYELASLKRAFEAANL 208 Query 820 PSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQP 871 P+ + + P+L L L +P++RP I+ ++P Sbjct 209 PALVLKIMSGTFAPISDRYSPELRQLILNMLNLDPSKRPQLNEIMAHAICIRP 261 >sp|P51952|CDK7_RAT Cyclin-dependent kinase 7 (Fragment) OS=Rattus norvegicus OX=10116 GN=Cdk7 PE=1 SV=2 Length=329 Score = 204 bits (518), Expect = 5e-57, Method: Composition-based stats. Identities = 69/305 (23%), Positives = 121/305 (40%), Gaps = 35/305 (11%) Query 902 DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGW----KQEIDILRTLYHE 957 LGEG F V Y + T ++VA+K +K + + G +EI +L+ L H Sbjct 9 FLGEGQFATV----YKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHP 64 Query 958 HIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI--GLAQLLLFAQQICEGMAYLH 1015 +II + ++ LV +++ L + +S+ + + + +G+ YLH Sbjct 65 NIIGLLDAFGHKS--NISLVFDFME-TDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 121 Query 1016 AQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKE 1075 +HRDL N+LLD + ++K+ DFGLAK+ + Y + ++ APE L Sbjct 122 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNWAYTHQ---VVTRWYRAPELLFG 178 Query 1076 -YKFYYASDVWSFGVTLYELLTH-----CDSSQSPPTKFLELIGIA--QGQMTVLRLTEL 1127 + D+W+ G L ELL DS T+ E +G + + L + Sbjct 179 ARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDY 238 Query 1128 LERGERLPRPDK-----CPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPS 1182 + P + ++ L++ + R T + KY P Sbjct 239 VTFKSFPGIPLQHIFIAAGDDLLELIQGLFLFNPCTRITASQ------ALRTKYFSNRPG 292 Query 1183 VFSVC 1187 C Sbjct 293 PTPGC 297 Score = 156 bits (394), Expect = 1e-40, Method: Composition-based stats. Identities = 47/264 (18%), Positives = 86/264 (33%), Gaps = 42/264 (16%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHH 649 +L LG+G VY+ RD+ V +K + H Sbjct 5 EKLDFLGEGQFATVYKA------------------------RDKNTNQIVAIKKIKLGHR 40 Query 650 DIALA-----FYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 A L+ ++SH ++ + +V +++E L+V ++ Sbjct 41 SEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFME-TDLEVIIKDNSL 99 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 + + L YL ++H ++ N+LL G+ +KL+D G+ Sbjct 100 VLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGV-------LKLADFGLAK 152 Query 765 GALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 S +V + APE L GA +D W G L E+ Sbjct 153 SFGSPNWAYTHQVVTRWYRAPELLF-GARMYGVGVDMWAVGCILAELLLRVPFLPGDSDL 211 Query 821 SEKEHFYQRQHRLPEPSCPQLATL 844 + ++ E P + +L Sbjct 212 DQLTRIFETLGTPTEEQWPDMCSL 235 >sp|Q8BSK8|KS6B1_MOUSE Ribosomal protein S6 kinase beta-1 OS=Mus musculus OX=10090 GN=Rps6kb1 PE=1 SV=2 Length=525 Score = 210 bits (534), Expect = 5e-57, Method: Composition-based stats. Identities = 70/292 (24%), Positives = 115/292 (39%), Gaps = 26/292 (9%) Query 872 HNLADVLTVNPDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKA 931 + ++ S P + +R LG+G +GKV T TG++ A+K Sbjct 66 MEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKV 124 Query 932 LKADC---GPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRD 988 LK + + K E +IL + H I+ + G+ L L++EY+ G L Sbjct 125 LKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGK--LYLILEYLSGGELFM 182 Query 989 YLPRHSIG-LAQLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKA 1047 L R I + +I + +LH + I+RDL N++L++ VK+ DFGL K Sbjct 183 QLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCK- 241 Query 1048 VPEGHEYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTK 1107 E V + + APE L A D WS G +Y++LT Sbjct 242 --ESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTG---- 295 Query 1108 FLELIGIAQGQMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFR 1159 + T+ ++ + +L P E L+K + A+ R Sbjct 296 -------ENRKKTIDKILKC-----KLNLPPYLTQEARDLLKKLLKRNAASR 335 Score = 154 bits (389), Expect = 3e-38, Method: Composition-based stats. Identities = 52/280 (19%), Positives = 99/280 (35%), Gaps = 33/280 (12%) Query 582 HRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVL 641 ++ + L LG+G V++ R +V G+ + M + R+ Sbjct 84 EKIRPECFELLRVLGKGGYGKVFQVR-KVTGANTGKIFAMKVLKKAMIVRNAK------- 135 Query 642 KVLDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRR 701 D +H E H + + G + ++ EY+ G L + L R Sbjct 136 ---DTAHTKAERNILEEV------KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER 186 Query 702 ERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPG 761 E G +++ AL +L K +++ ++ NI+L G +KL+D G Sbjct 187 E-GIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG-------HVKLTDFG 238 Query 762 VGLGALSR----EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQS 817 + ++ I ++APE L + + A+D W GA + ++ G P Sbjct 239 LCKESIHDGTVTHTFCGTIEYMAPEILM--RSGHNRAVDWWSLGALMYDML-TGAPPFTG 295 Query 818 RSPSEKEHFYQRQH-RLPEPSCPQLATLTSQCLTYEPTQR 856 + + + LP + L + L R Sbjct 296 ENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASR 335 >sp|P10665|KS6AA_XENLA Ribosomal protein S6 kinase 2 alpha OS=Xenopus laevis OX=8355 GN=rps6ka PE=1 SV=1 Length=733 Score = 214 bits (546), Expect = 5e-57, Method: Composition-based stats. Identities = 64/259 (25%), Positives = 113/259 (44%), Gaps = 24/259 (9%) Query 903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGP-QHRSGWKQEIDILRTLYHEHIIK 961 LG+G FGKV L T ++ A+K LK + R K E DIL ++H +++ Sbjct 68 LGQGSFGKVFLVR-KITPPDANQLYAMKVLKKATLKVRDRVRTKMERDILADVHHPFVVR 126 Query 962 YKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYLHAQHYI 1020 Q E L L+++++ G L L + + + ++ G+ +LH+ I Sbjct 127 LHYAF--QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGII 184 Query 1021 HRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEYKFYY 1080 +RDL N+LLD + +K+ DFGL+K E ++ + V + APE + + Sbjct 185 YRDLKPENILLDEEGHIKLTDFGLSK---EAIDHEKKAYSFCGTVEYMAPEVVNRQGHSH 241 Query 1081 ASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERLPRPDKC 1140 ++D WS+GV ++E+LT Q K + + +L P Sbjct 242 SADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILK----------------AKLGMPQFL 285 Query 1141 PCEVYHLMKNCWETEASFR 1159 E L++ ++ + R Sbjct 286 SNEAQSLLRALFKRNPTNR 304 Score = 188 bits (478), Expect = 3e-48, Method: Composition-based stats. Identities = 58/290 (20%), Positives = 102/290 (35%), Gaps = 29/290 (10%) Query 884 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG 943 + +G G + + GT AVK + + + Sbjct 403 PKTHSKNILFMDVYTVRETIGVGSYSVCKRC----VHKGTNMEYAVKVI-----DKTKRD 453 Query 944 WKQEIDILRTL-YHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSI-GLAQLL 1001 +EI+ILR H +II K ++ S+ +V E + G L D + R + Sbjct 454 PSEEIEILRRYGQHPNIIALKDVYKEGN--SIYVVTELMRGGELLDRILRQKFFSEREAS 511 Query 1002 LFAQQICEGMAYLHAQHYIHRDLAARNVL-LDNDRL---VKIGDFGLAKAVPEGHEYYRV 1057 +C+ + LH+Q +HRDL N+L +D ++I DFG AK + + Sbjct 512 SVLFTVCKTVENLHSQGVVHRDLKPSNILYVDESGDPESIRICDFGFAKQLRADNGLLMT 571 Query 1058 REDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQG 1117 + APE LK + D+WS G+ LY +L + L + Sbjct 572 ---PCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANG------LGDTPEE 622 Query 1118 QMTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 + + + RG + L+ + R T + ++ Sbjct 623 ILARIGSGKFTLRGGNW---NTVSAAAKDLVSRMLHVDPHKRLTAKQVLQ 669 Score = 174 bits (441), Expect = 1e-43, Method: Composition-based stats. Identities = 63/344 (18%), Positives = 118/344 (34%), Gaps = 40/344 (12%) Query 568 RASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPL 627 + P T ++ + S + DQ + L LGQG+ V+ + D + L Sbjct 42 KEFPITHHVKEGS-EKADQSDFVLLKVLGQGSFGKVFL----------VRKITPPDANQL 90 Query 628 VPGRDRGQELRVVLKVLDPSHHDIALAFYE--TASLMSQVSHTHLAFVHGVCVRGPENIM 685 +KVL + + +++ V H + +H + + Sbjct 91 Y-----------AMKVLKKATLKVRDRVRTKMERDILADVHHPFVVRLHYAFQTEGKLYL 139 Query 686 VTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARL 745 + +++ G L L +E K +A +LA L +L + +++ ++ NILL Sbjct 140 ILDFLRGGDLFTRLSKEVMFTEEDVKFYLA-ELALGLDHLHSLGIIYRDLKPENILLDEE 198 Query 746 GLAEGTSPFIKLSDPGVGLGALSREER----VERIPWLAPECLPGGANSLSTAMDKWGFG 801 G IKL+D G+ A+ E++ + ++APE + +S S D W +G Sbjct 199 G-------HIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHS--ADWWSYG 249 Query 802 ATLLEICFDGEAPLQSRSPSEKEHFYQRQHR-LPEPSCPQLATLTSQCLTYEPTQRPSFR 860 + E+ G P Q + E + +P+ + +L PT R Sbjct 250 VLMFEML-TGSLPFQGKDRKETMTLILKAKLGMPQFLSNEAQSLLRALFKRNPTNRLGSA 308 Query 861 TILRDLTRLQPHNLADVLTVNPDSPASDPTVFHKRYLKKIRDLG 904 + + QP S P Sbjct 309 MEGAEEIKRQPFFSTIDWNKLFRREMSPPFKPAVTQADDTYYFD 352 Score = 147 bits (370), Expect = 7e-35, Method: Composition-based stats. Identities = 49/278 (18%), Positives = 92/278 (33%), Gaps = 28/278 (10%) Query 605 EGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETASLMSQ 664 + L ++ E + +G + +KV+D + D + E ++ + Sbjct 408 KNILFMDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKTKRDPS----EEIEILRR 463 Query 665 V-SHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPMAWKMVVAQQLASALS 723 H ++ + V G +VTE + G L + R++ V + + Sbjct 464 YGQHPNIIALKDVYKEGNSIYVVTELMRGGELLDRILRQKF-FSEREASSVLFTVCKTVE 522 Query 724 YLENKNLVHGNVCGRNIL-LARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWL--- 779 L ++ +VH ++ NIL + G E I++ D G + + + Sbjct 523 NLHSQGVVHRDLKPSNILYVDESGDPES----IRICDFGFAKQLRADNGLLMTPCYTANF 578 Query 780 -APECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQ---SRSPSEKE------HFYQR 829 APE L D W G L + G P +P E F R Sbjct 579 VAPEVLK--RQGYDEGCDIWSLGILLYTMLA-GYTPFANGLGDTPEEILARIGSGKFTLR 635 Query 830 QHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLT 867 L S+ L +P +R + + +L+ Sbjct 636 GGN-WNTVSAAAKDLVSRMLHVDPHKRLTAKQVLQHEW 672 >sp|Q06BH3|SRF1_ARATH Protein STRUBBELIG-RECEPTOR FAMILY 1 OS=Arabidopsis thaliana OX=3702 GN=SRF1 PE=1 SV=2 Length=775 Score = 215 bits (548), Expect = 5e-57, Method: Composition-based stats. Identities = 73/372 (20%), Positives = 144/372 (39%), Gaps = 32/372 (9%) Query 822 EKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVN 881 E + + S P + + ++ EP + RT + L V ++ Sbjct 415 EIDMNGNAMDLMHPSSIPPIKRVIAK--ATEPAEASLKRTTSKSHGPLTAVKHFTVASLQ 472 Query 882 PDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHR 941 + + +G G G V G++ AV+ L Sbjct 473 QHTNSFSHENL----------IGTGMLGSVYRAELPG-----GKLFAVRKLDKKSPNHEE 517 Query 942 SG-WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLP-----RHSI 995 G + + ++ + + H +I++ G C + ++ L+ EY G+L D L + + Sbjct 518 EGKFLELVNNIDRIRHANIVQLVGFCSEHSQR--LLIHEYCRNGTLHDLLHIDDRLKIEL 575 Query 996 GLAQLLLFAQQICEGMAYLHA---QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGH 1052 + A + + + YLH IHR+ + N+LLD+D V + D GLA + G Sbjct 576 SWNVRVRIALEAAKALEYLHEICDPPSIHRNFKSANILLDDDIRVHVSDCGLAPLISSG- 634 Query 1053 EYYRVREDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLE-L 1111 ++ + + APE + + DV+SFGV + ELLT S + + L Sbjct 635 AVSQLSGQLLAAYGYGAPE-FEYGIYTMKCDVYSFGVVMLELLTGRKSYDKKRDRGEQFL 693 Query 1112 IGIAQGQM-TVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILK 1170 + A Q+ + L ++++ + P K ++ C ++E +RP ++ L Sbjct 694 VRWAIPQLHDIDALAKMVDPSLKGDYPAKSLSHFADVISRCVQSEPEYRPLMSEVVQDLS 753 Query 1171 TVHEKYQGQAPS 1182 + ++ + S Sbjct 754 DMIQREHRRNDS 765 Score = 165 bits (418), Expect = 1e-40, Method: Composition-based stats. Identities = 58/352 (16%), Positives = 116/352 (33%), Gaps = 70/352 (20%) Query 566 GARASPRTLNLSQLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDED 625 G + + ++ L H + + +G G +VY L Sbjct 458 GPLTAVKHFTVASLQQH---TNSFSHENLIGTGMLGSVYRAELPGGKLF----------- 503 Query 626 PLVPGRDRGQELRVVLKVLDPSHHDIALA--FYETASLMSQVSHTHLAFVHGVCVRGPEN 683 ++ LD + F E + + ++ H ++ + G C + Sbjct 504 --------------AVRKLDKKSPNHEEEGKFLELVNNIDRIRHANIVQLVGFCSEHSQR 549 Query 684 IMVTEYVEHGPLDVWLR-RERGHVPMAW--KMVVAQQLASALSYLEN---KNLVHGNVCG 737 +++ EY +G L L +R + ++W ++ +A + A AL YL +H N Sbjct 550 LLIHEYCRNGTLHDLLHIDDRLKIELSWNVRVRIALEAAKALEYLHEICDPPSIHRNFKS 609 Query 738 RNILLARLGLAEGTSPFIKLSDPGVGLGALS------REERVERIPWLAPECLPGGANSL 791 NILL + +SD G+ S + + + APE Sbjct 610 ANILLD-------DDIRVHVSDCGLAPLISSGAVSQLSGQLLAAYGYGAPE---FEYGIY 659 Query 792 STAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPS-------------- 837 + D + FG +LE+ ++ + R E+ +L + Sbjct 660 TMKCDVYSFGVVMLELLTGRKSYDKKRDRGEQFLVRWAIPQLHDIDALAKMVDPSLKGDY 719 Query 838 ----CPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDSP 885 A + S+C+ EP RP +++DL+ + + + Sbjct 720 PAKSLSHFADVISRCVQSEPEYRPLMSEVVQDLSDMIQREHRRNDSNGDNQY 771 >sp|Q8IWQ3|BRSK2_HUMAN Serine/threonine-protein kinase BRSK2 OS=Homo sapiens OX=9606 GN=BRSK2 PE=1 SV=3 Length=736 Score = 215 bits (547), Expect = 5e-57, Method: Composition-based stats. Identities = 71/282 (25%), Positives = 119/282 (42%), Gaps = 29/282 (10%) Query 889 PTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADC-GPQHRSGWKQE 947 + + + LG+G G V L + T + VA+K + + ++E Sbjct 11 QHAQYVGPYRLEKTLGKGQTGLVKLG----VHCVTCQKVAIKIVNREKLSESVLMKVERE 66 Query 948 IDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL-PRHSIGLAQLLLFAQQ 1006 I IL+ + H H++K E++ K L LV+E+V G L DYL + + + F +Q Sbjct 67 IAILKLIEHPHVLKLHDVYENK--KYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 124 Query 1007 ICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVF 1066 I + + H+ HRDL N+LLD ++I DFG+A + E Sbjct 125 IISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASL----QVGDSLLETSCGSPH 180 Query 1067 WYAPECLKEYKFY-YASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLT 1125 + PE ++ K+ +DVWS GV L+ LL + +L Sbjct 181 YACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDD---------------NLRQLL 225 Query 1126 ELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIP 1167 E ++RG P P + L++ E +A+ R T E++ Sbjct 226 EKVKRGV-FHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQK 266 Score = 166 bits (420), Expect = 5e-41, Method: Composition-based stats. Identities = 48/300 (16%), Positives = 98/300 (33%), Gaps = 40/300 (13%) Query 590 TQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPS-- 647 LG+G V G V +V +K+++ Sbjct 20 RLEKTLGKGQTGLVKLGVHCVTCQ------------------------KVAIKIVNREKL 55 Query 648 HHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVP 707 + + +++ + H H+ +H V +V E+V G L +L ++G + Sbjct 56 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYL-VKKGRLT 114 Query 708 MAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGAL 767 +Q+ SAL + + ++ H ++ N+LL I+++D G+ + Sbjct 115 PKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKN-------NIRIADFGMASLQV 167 Query 768 SR---EERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKE 824 E + PE + G D W G L + G P + + Sbjct 168 GDSLLETSCGSPHYACPEVIRGEKYD-GRKADVWSCGVILFALLV-GALPFDDDNLRQLL 225 Query 825 HFYQRQ-HRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD 883 +R +P P +L + + +R + I + + + N + P Sbjct 226 EKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWYIGGKNEPEPEQPIPR 285 >sp|Q2QAV0|TIO_ARATH Serine/threonine-protein kinase TIO OS=Arabidopsis thaliana OX=3702 GN=TIO PE=1 SV=1 Length=1322 Score = 220 bits (560), Expect = 5e-57, Method: Composition-based stats. Identities = 74/267 (28%), Positives = 114/267 (43%), Gaps = 28/267 (10%) Query 897 LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVK-ALKADCGPQHRSGWKQEIDILRTLY 955 I +GEG FG+V Y TG+ VA+K +K + +QEI+ILR L Sbjct 6 YHVIELVGEGSFGRV----YKGRRKYTGQTVAMKFIMKQGKTDKDIHSLRQEIEILRKLK 61 Query 956 HEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS-IGLAQLLLFAQQICEGMAYL 1014 HE+II+ E+ E +V E+ G L + L + Q+ A+Q+ + + YL Sbjct 62 HENIIEMLDSFENARE--FCVVTEFAQ-GELFEILEDDKCLPEEQVQAIAKQLVKALDYL 118 Query 1015 HAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLK 1074 H+ IHRD+ +N+L+ +VK+ DFG A+A+ V + APE +K Sbjct 119 HSNRIIHRDMKPQNILIGAGSVVKLCDFGFARAMSTN---TVVLRSIKGTPLYMAPELVK 175 Query 1075 EYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTVLRLTELLERGERL 1134 E + D+WS GV LYEL + +V L + + + Sbjct 176 EQPYDRTVDLWSLGVILYELYVGQPPFYT---------------NSVYALIRHIVKDP-V 219 Query 1135 PRPDKCPCEVYHLMKNCWETEASFRPT 1161 PD+ +K E R T Sbjct 220 KYPDEMSTYFESFLKGLLNKEPHSRLT 246 Score = 182 bits (462), Expect = 3e-45, Method: Composition-based stats. Identities = 49/276 (18%), Positives = 98/276 (36%), Gaps = 41/276 (15%) Query 587 KEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLK-VLD 645 ++ + +G+G+ VY+GR + G V +K ++ Sbjct 4 EDYHVIELVGEGSFGRVYKGRRKYTGQ------------------------TVAMKFIMK 39 Query 646 PSHHDIAL-AFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERG 704 D + + + ++ ++ H ++ + E +VTE+ + G L L ++ Sbjct 40 QGKTDKDIHSLRQEIEILRKLKHENIIEMLDSFENAREFCVVTEFAQ-GELFEILEDDKC 98 Query 705 HVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGL 764 +P +A+QL AL YL + ++H ++ +NIL+ G +KL D G Sbjct 99 -LPEEQVQAIAKQLVKALDYLHSNRIIHRDMKPQNILI-------GAGSVVKLCDFGFAR 150 Query 765 GALSRE----ERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSP 820 + ++APE + +D W G L E+ + Sbjct 151 AMSTNTVVLRSIKGTPLYMAPELVKE--QPYDRTVDLWSLGVILYELYVGQPPFYTNSVY 208 Query 821 SEKEHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQR 856 + H + + P+ + L EP R Sbjct 209 ALIRHIVKDPVKYPDEMSTYFESFLKGLLNKEPHSR 244 >sp|O73792|TIE1_DANRE Tyrosine-protein kinase receptor Tie-1 (Fragment) OS=Danio rerio OX=7955 GN=tie1 PE=1 SV=1 Length=184 Score = 198 bits (503), Expect = 5e-57, Method: Composition-based stats. Identities = 69/180 (38%), Positives = 91/180 (51%), Gaps = 18/180 (10%) Query 999 QLLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVR 1058 QLL FA + GM YL + +IHRDLAARNVL+ ++ + KI DFGL++ G E Y + Sbjct 1 QLLQFAADVATGMHYLSDKQFIHRDLAARNVLVGDNLVAKIADFGLSR----GEEVYVKK 56 Query 1059 EDGDSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQ 1118 G PV W A E L + SDVWSFGV L+E+++ L G Sbjct 57 TMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVS--------------LGGTPYCG 102 Query 1119 MTVLRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQG 1178 MT L E L +G R+ +P C EVY LM+ CW RP F + L + E + Sbjct 103 MTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRMQEARKA 162 Score = 160 bits (405), Expect = 9e-44, Method: Composition-based stats. Identities = 46/183 (25%), Positives = 79/183 (43%), Gaps = 14/183 (8%) Query 710 WKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLG-ALS 768 + A +A+ + YL +K +H ++ RN+L+ G + K++D G+ G + Sbjct 1 QLLQFAADVATGMHYLSDKQFIHRDLAARNVLV-------GDNLVAKIADFGLSRGEEVY 53 Query 769 REERVERIP--WLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHF 826 ++ + R+P W+A E L + +T D W FG L EI G P + +E Sbjct 54 VKKTMGRLPVRWMAIESL--NYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEK 111 Query 827 YQRQHRL--PEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPDS 884 + +R+ P ++ L QC P +RP F I L R+Q A V ++ Sbjct 112 LPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRMQEARKAYVNMALFEN 171 Query 885 PAS 887 Sbjct 172 FTY 174 Lambda K H a alpha 0.318 0.134 0.397 0.792 4.96 Gapped Lambda K H a alpha sigma 0.267 0.0410 0.140 1.90 42.6 43.6 Effective search space used: 140973851148 Database: uniprot_sprot.fasta Posted date: Aug 1, 2024 3:29 PM Number of letters in database: 207,016,062 Number of sequences in database: 571,864 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40